Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A1BG ENSG00000121410 "Alpha-1-B glycoprotein" P04217 19 58345178-58353492 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1493 "liver: 1224.7" "Cell type enriched" "Detected in many" 13 "Hepatocytes: 1548.5" "Cancer enriched" "Detected in single" 85 "liver cancer: 22.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;RH-30: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB016673, HPA044252" Supported "Secreted to blood" NA NA 200000000000 51000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016673: AB_1611892, HPA044252: AB_2678876" "unprognostic (9.95e-2)" "unprognostic (5.31e-2)" "unprognostic (3.67e-2)" "unprognostic (3.44e-2)" "unprognostic (1.18e-1)" "unprognostic (1.66e-2)" "prognostic favorable (3.97e-4)" "unprognostic (1.09e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-1)" "unprognostic (1.47e-2)" "unprognostic (1.37e-2)" "unprognostic (4.19e-5)" "unprognostic (2.37e-2)" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (6.72e-2)" 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.8 0.1 0.2 0.0 0.0 0.1 1224.7 0.1 0.3 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.6 0.0 2.5 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.8 0.3 0.0 0.0 0.9 0.3 0.8 0.0 0.1 0.1 0.7 1.3 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.3 0.4 0.0 0.6 0.2 0.0 0.0 0.9 0.9 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 10.2 12.8 14.1 0.7 50.2 8.8 2.2 16.2 12.0 3.4 52.0 64.3 0.7 27.1 10.6 22.0 2.1 1.0 71.2 0.0 7.9 0.9 0.6 5.0 52.6 10.9 1.2 56.2 2.2 9.2 15.6 20.3 5.1 2.1 17.7 10.8 43.2 1548.5 25.1 8.4 1.7 0.1 20.3 110.9 66.0 2.1 1.2 49.4 115.6 0.0 60.8 3.1 15.5 0.0 8.7 5.4 0.0 1.2 94.4 11.1 0.0 2.0 15.0 5.5 26.3 29.2 43.8 4.1 7.9 1.5 3.7 1.9 52.6 0.7 0.2 0.6 A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1319.0;Endothelial cells: 797.7;Hepatic stellate cells: 526.1;Hepatocytes: 910.1;Horizontal cells: 681.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Group enriched" "Detected in some" 5 "AF22: 772.0;ASC diff: 223.5;Hep G2: 649.8;SK-MEL-30: 230.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" 451.5 182.3 157.5 149.8 158.5 5.6 295.3 169.3 223.5 227.2 163.3 257.0 141.2 306.2 244.1 218.3 228.4 452.4 312.8 149.8 175.0 311.4 1250.0 1678.3 98.2 192.9 167.6 101.7 91.5 153.7 135.3 445.2 193.0 293.8 316.3 129.9 131.8 226.7 147.8 71.5 182.7 520.0 196.2 240.6 171.6 58.9 190.7 53.9 202.7 285.6 59.2 847.0 160.2 192.7 0.3 0.0 772.0 0.0 223.5 16.2 2.0 93.1 25.5 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 10.1 649.8 0.0 0.8 0.8 36.9 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.0 0.2 2.0 3.3 0.0 0.1 1.8 0.9 0.8 0.0 0.3 0.3 0.7 1.8 0.0 230.1 3.2 0.0 0.3 0.3 0.1 6.7 1.5 0.5 0.7 0.3 0.7 0.2 0.5 15.4 0.0 0.1 0.0 1.5 0.0 0.8 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 157.5 158.5 169.3 223.5 149.8 175.0 192.9 167.6 193.0 196.2 190.7 192.7 1319.0 12.8 85.6 5.2 9.0 19.5 2.3 0.0 12.0 5.5 10.8 95.5 106.1 22.8 6.8 1.8 8.4 2.5 8.1 0.0 0.0 0.2 18.8 8.3 54.7 797.7 0.0 45.9 3.2 5.5 2.9 241.3 9.2 14.7 27.8 2.5 526.1 910.1 233.0 681.4 2.9 0.0 0.0 123.1 41.4 36.8 77.3 130.7 23.2 355.1 37.8 6.1 1.0 5.5 4.7 0.2 0.0 141.4 11.2 4.7 0.0 0.3 4.4 21.2 335.2 22.1 328.0 2.7 8.8 8.2 14.1 4.1 13.0 73.3 0.0 3.6 A2ML1 "CPAMD9, FLJ25179, p170" ENSG00000166535 "Alpha-2-macroglobulin like 1" A8K2U0 12 8822621-8887001 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 556.3;vagina: 204.8" "Cell type enriched" "Detected in some" 6 "Squamous epithelial cells: 127.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 39.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 10.9;hTCEpi: 5.5;SK-BR-3: 13.9" "Low region specificity" "Detected in many" "HPA038847, HPA038848" Enhanced "Secreted in other tissues" NA NA 10000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038847: AB_2676236, HPA038848: AB_10672654" "unprognostic (1.13e-2)" "unprognostic (7.64e-2)" "unprognostic (1.04e-2)" "unprognostic (9.46e-3)" "unprognostic (2.14e-1)" "unprognostic (5.54e-3)" "unprognostic (4.59e-2)" "unprognostic (7.58e-3)" "unprognostic (2.63e-1)" "unprognostic (1.57e-1)" "unprognostic (1.15e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-9)" "unprognostic (2.28e-1)" "unprognostic (3.07e-1)" "unprognostic (5.88e-2)" "unprognostic (2.42e-2)" 0.2 0.1 2.1 0.0 2.1 0.2 4.1 0.8 2.4 116.5 0.6 0.1 0.0 0.5 0.4 556.3 0.7 0.2 0.4 2.0 2.2 0.1 0.3 0.1 0.2 1.8 3.1 0.4 0.2 0.8 1.4 0.7 1.3 0.6 0.0 0.7 99.0 0.0 0.3 72.0 0.1 0.1 1.7 0.1 0.7 5.0 4.3 3.0 0.1 0.0 51.5 1.1 204.8 1.5 0.1 0.0 0.1 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.1 0.2 0.1 0.2 0.0 2.5 10.9 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 13.9 0.0 1.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 2.1 2.1 0.8 2.4 2.0 2.2 1.8 3.1 1.3 1.7 4.3 1.5 0.0 0.0 0.0 20.2 0.0 0.4 0.5 1.0 1.8 0.7 0.3 0.1 0.7 0.0 2.2 0.0 0.0 0.3 0.0 0.0 1.9 0.0 0.4 4.4 0.9 0.3 0.0 0.0 4.9 0.0 0.5 0.4 0.0 11.9 0.0 0.8 0.0 0.0 0.1 0.0 4.6 0.0 0.0 0.0 0.0 0.6 0.3 0.2 0.0 0.0 0.0 1.2 0.0 2.0 0.5 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.2 0.3 0.0 0.4 0.3 1.0 0.4 127.6 12.6 0.1 0.1 1.9 0.0 8.2 A4GNT alpha4GnT ENSG00000118017 Alpha-1,4-N-acetylglucosaminyltransferase Q9UNA3 3 138123713-138132390 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "stomach 1: 23.6" "Group enriched" "Detected in some" 25 "Cholangiocytes: 4.3;Gastric mucus-secreting cells: 16.3" "Group enriched" "Detected in some" 6 "pancreatic cancer: 2.5;stomach cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA008017 Enhanced "Intracellular and membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA008017: AB_1078073" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "unprognostic (2.14e-1)" "unprognostic (1.18e-2)" "unprognostic (1.48e-2)" "unprognostic (8.79e-2)" "unprognostic (9.35e-2)" "unprognostic (1.97e-1)" "unprognostic (1.81e-1)" "unprognostic (1.85e-1)" "unprognostic (4.03e-2)" "unprognostic (1.03e-1)" "unprognostic (7.79e-2)" "unprognostic (2.55e-2)" "unprognostic (6.48e-3)" 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.1 2.7 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.4 0.1 0.2 0.0 0.2 0.4 0.1 3.2 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.2 23.6 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AADAC "CES5A1, DAC" ENSG00000114771 "Arylacetamide deacetylase" P22760 3 151814073-151828488 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 224.9;intestine: 241.7;liver: 946.7" "Group enriched" "Detected in some" 8 "Hepatocytes: 687.7;Proximal enterocytes: 460.5" "Cancer enriched" "Detected in many" 22 "liver cancer: 153.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 9.5;ASC diff: 4.2;EFO-21: 4.6;HBEC3-KT: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA002911 Approved NA NA "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" "HPA002911: AB_1078074" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.11e-2)" "unprognostic (4.41e-2)" "unprognostic (9.23e-2)" "unprognostic (7.82e-2)" "unprognostic (2.15e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.58e-6)" "prognostic unfavorable (5.02e-4)" "prognostic unfavorable (2.19e-4)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" 8.2 224.9 0.0 0.4 0.0 0.0 5.0 0.0 0.1 0.1 0.2 0.3 220.9 0.2 0.0 2.7 0.6 27.4 0.7 0.0 0.0 0.2 946.7 9.1 0.3 0.0 0.1 0.1 36.7 0.0 0.0 1.5 0.0 0.1 0.2 0.0 1.3 0.0 0.0 13.8 241.7 0.0 0.0 0.2 52.3 0.8 0.1 0.4 0.3 0.0 2.5 0.7 0.4 0.0 0.0 9.5 0.0 0.0 4.2 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.1 4.6 0.0 0.0 0.2 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.1 1.0 0.4 0.1 0.3 1.7 0.0 1.7 0.1 1.2 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.0 2.0 0.9 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 6.5 0.0 14.3 0.0 0.7 0.3 0.0 4.4 0.0 0.0 0.0 0.0 1.1 71.4 8.7 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.3 1.8 0.1 0.7 0.0 2.7 0.0 51.9 0.0 39.3 53.5 0.2 0.0 0.0 5.0 687.7 0.2 0.0 0.0 9.6 0.0 14.8 0.3 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 10.0 0.0 0.1 0.2 460.5 0.0 2.9 0.0 0.0 0.0 3.4 0.0 0.1 1.4 3.4 0.3 0.7 0.3 18.4 0.2 AADACL2 MGC72001 ENSG00000197953 "Arylacetamide deacetylase like 2" Q6P093 3 151733916-151761339 "Predicted secreted proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "skin 1: 35.6" "Cell type enriched" "Detected in some" 7 "Suprabasal keratinocytes: 30.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.20e-2)" "unprognostic (3.10e-3)" "unprognostic (2.63e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (3.00e-1)" "unprognostic (2.91e-4)" 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 35.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 30.7 0.1 0.1 0.0 0.0 0.0 AAMP ENSG00000127837 "Angio associated migratory cell protein" Q13685 2 218264129-218270178 "Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017717, HPA031868" Approved Supported Microtubules,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Microtubules Cytosol "CAB017717: , HPA031868: AB_2674078" "unprognostic (1.57e-1)" "unprognostic (6.12e-2)" "unprognostic (8.11e-3)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.39e-2)" "unprognostic (5.04e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (8.94e-2)" "unprognostic (7.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (4.22e-2)" "unprognostic (5.51e-2)" "unprognostic (1.23e-3)" "unprognostic (5.26e-2)" "unprognostic (1.92e-1)" "unprognostic (9.09e-2)" 66.5 66.4 65.0 46.2 66.1 27.5 65.2 67.1 80.1 62.6 63.2 76.3 62.8 61.7 43.8 75.1 60.8 56.1 65.4 65.7 67.2 60.2 77.5 46.6 47.8 69.2 66.6 79.8 70.7 72.7 62.1 54.9 66.4 58.0 58.0 38.4 66.9 58.7 90.4 76.6 61.7 50.7 67.5 53.0 86.9 53.8 67.1 54.0 66.6 62.0 52.6 70.0 57.4 70.3 126.1 104.6 75.1 102.2 111.9 75.7 146.0 89.6 136.3 167.1 124.5 226.2 100.1 64.6 121.8 112.6 158.8 94.3 150.7 133.4 129.3 103.5 200.9 147.4 108.2 237.4 158.9 139.3 92.4 97.8 152.7 172.2 149.7 99.7 97.6 124.3 202.6 82.4 108.9 198.0 112.4 234.9 121.0 182.4 75.4 90.6 97.5 105.8 100.3 160.5 96.2 92.9 59.4 128.7 134.7 119.1 99.1 104.6 84.7 110.2 82.3 81.2 106.8 105.7 198.1 108.4 111.0 88.6 77.4 75.9 166.2 60.3 101.1 209.2 105.1 100.3 90.1 94.9 191.4 105.7 111.1 100.7 26.2 114.9 210.6 114.1 109.3 179.4 65.0 66.1 67.1 80.1 65.7 67.2 69.2 66.6 66.4 67.5 67.1 70.3 57.8 41.7 35.2 11.4 50.4 90.5 86.1 122.9 66.0 47.7 50.7 45.2 35.5 41.5 74.0 42.3 12.5 160.0 42.2 74.3 103.7 95.7 3.5 33.5 46.4 50.6 75.5 34.0 11.5 95.4 130.3 63.4 80.5 38.2 34.8 57.6 42.5 46.2 91.9 63.9 12.9 89.9 93.6 37.0 65.3 8.8 83.3 38.5 62.2 5.6 64.8 80.2 41.2 8.0 10.5 86.6 72.0 74.9 51.2 116.0 99.5 85.3 47.4 37.1 65.7 38.4 86.5 72.0 53.3 70.2 97.3 202.6 44.4 62.5 103.5 119.9 AANAT SNAT ENSG00000129673 "Aralkylamine N-acetyltransferase" Q16613 17 76453351-76470117 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Melatonin biosynthesis" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 11.0;testis: 4.7" "Cell type enriched" "Detected in some" 10 "Bipolar cells: 302.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.5;Daudi: 2.0;SCLC-21H: 3.2;U-266/70: 2.3;U-266/84: 2.7;U-698: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054321 Supported Cytosol "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA054321: AB_2682449" "unprognostic (7.89e-2)" "unprognostic (2.62e-1)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.83e-2)" "unprognostic (2.03e-2)" "unprognostic (1.05e-2)" "unprognostic (3.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.61e-1)" "unprognostic (9.30e-2)" "unprognostic (4.19e-1)" "unprognostic (2.81e-7)" "unprognostic (1.04e-1)" "unprognostic (6.00e-2)" "unprognostic (4.47e-2)" "unprognostic (1.34e-2)" 0.1 0.2 0.7 1.6 0.7 1.2 0.0 0.8 1.1 0.1 0.2 0.1 0.1 0.1 0.1 0.3 0.2 0.7 0.1 0.9 0.9 0.3 0.0 0.2 1.5 2.1 1.7 0.2 0.2 0.0 0.3 0.0 2.0 0.1 0.0 11.0 0.1 0.0 0.1 1.4 0.4 0.0 1.2 1.0 0.2 4.7 2.1 0.0 0.4 0.0 0.1 0.2 0.1 1.4 0.5 2.5 0.3 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 1.7 2.0 0.3 0.0 0.3 0.6 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.2 0.0 1.0 0.2 0.3 0.0 0.1 0.6 0.8 0.2 0.1 0.1 1.1 0.0 0.0 3.2 0.2 0.0 0.1 0.8 0.3 1.5 0.3 0.0 0.0 0.9 0.1 0.0 2.3 2.7 3.6 0.6 0.2 0.4 0.7 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.7 0.7 0.8 1.1 0.9 0.9 2.1 1.7 2.0 1.2 2.1 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 302.1 0.1 0.4 0.3 0.0 0.0 0.0 12.5 0.3 0.2 0.0 0.0 0.0 7.5 0.2 0.1 0.6 1.2 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 6.7 0.6 0.1 0.0 0.3 0.0 19.4 0.3 0.1 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.4 0.0 30.2 0.0 0.0 0.0 3.1 1.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 AATK "AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77" ENSG00000181409 "Apoptosis associated tyrosine kinase" Q6ZMQ8 17 81110487-81166221 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 184.7" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 243.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.0" "Group enriched" "Detected in some" 6 "CACO-2: 60.1;SH-SY5Y: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009073 Enhanced Uncertain Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA009073: AB_1078076" "unprognostic (3.47e-3)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-4)" "unprognostic (1.96e-1)" "unprognostic (1.94e-1)" "unprognostic (7.29e-2)" "unprognostic (9.85e-2)" "unprognostic (6.09e-2)" "unprognostic (4.27e-2)" "unprognostic (2.88e-3)" "unprognostic (2.48e-1)" "unprognostic (4.28e-6)" "unprognostic (1.58e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (4.57e-2)" 3.3 4.2 35.4 3.1 79.2 3.7 2.3 43.4 82.0 2.8 0.0 7.7 30.9 0.9 0.5 1.8 2.8 2.7 3.9 30.6 30.8 1.0 0.9 9.5 0.9 99.2 67.9 0.9 20.6 3.0 17.3 2.0 63.4 5.2 0.5 2.1 5.9 3.3 0.6 4.5 23.7 0.8 38.8 9.7 5.8 0.7 78.4 0.1 2.9 1.0 0.2 2.8 4.2 184.7 0.3 0.5 0.7 4.9 0.0 0.0 0.7 0.1 0.0 0.0 0.0 60.1 0.2 0.0 0.3 0.0 0.0 1.2 0.6 0.0 0.0 0.0 2.0 2.2 3.2 2.8 0.1 0.0 3.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 1.4 0.0 6.6 0.0 0.2 0.7 0.6 0.3 2.1 4.1 0.6 0.0 0.2 4.5 17.1 0.2 0.4 2.3 0.2 1.1 2.2 2.1 0.4 0.5 0.4 0.0 0.1 0.0 0.0 0.2 1.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 35.4 79.2 43.4 82.0 30.6 30.8 99.2 67.9 63.4 38.8 78.4 184.7 6.3 32.1 20.3 17.0 0.3 0.3 1.0 1.9 0.6 43.0 1.3 5.1 2.2 2.8 0.1 0.0 4.2 0.1 0.5 6.8 0.0 0.6 0.0 0.4 0.2 1.8 1.8 0.0 34.6 1.8 0.1 0.5 7.1 0.6 6.3 2.0 1.1 0.1 2.1 21.9 36.0 4.6 0.0 2.8 0.4 0.0 1.5 8.2 5.4 2.8 1.5 9.6 4.1 21.1 243.2 1.1 4.2 2.6 0.1 0.9 34.1 0.9 0.0 4.4 0.0 4.3 0.8 0.4 0.5 0.0 0.3 2.3 1.4 0.4 7.0 0.2 ABCG1 ABC8 ENSG00000160179 "ATP binding cassette subfamily G member 1" P45844 21 42199689-42297244 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 122.6;Syncytiotrophoblasts: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 35.5;neutrophil: 36.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.6" "Cell line enhanced" "Detected in many" "hTCEpi: 25.5;JURKAT: 38.4;MCF7: 33.2;MOLT-4: 31.5;OE19: 54.9;RPMI-8226: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031470, HPA031471" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "HPA031470: AB_10599188, HPA031471: AB_10600201" "unprognostic (2.89e-2)" "unprognostic (2.53e-2)" "unprognostic (9.96e-2)" "unprognostic (4.20e-3)" "unprognostic (2.87e-1)" "unprognostic (3.09e-2)" "unprognostic (5.74e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.66e-3)" "unprognostic (3.66e-3)" "unprognostic (6.37e-2)" "prognostic favorable (7.16e-6)" "unprognostic (1.40e-2)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.42e-2)" 17.2 37.7 18.3 12.1 25.5 8.1 15.2 14.4 20.2 8.1 20.0 14.1 17.5 4.9 3.9 4.1 6.3 13.8 10.5 15.5 17.0 10.2 6.3 29.4 18.1 12.0 19.9 6.3 5.3 24.4 10.7 13.7 13.3 6.2 15.0 29.1 16.1 7.0 19.6 16.8 22.0 4.0 12.2 31.2 15.9 1.1 20.3 18.9 8.5 6.2 12.1 12.9 5.0 24.7 0.0 6.0 4.6 2.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.1 1.9 0.8 0.0 0.7 0.9 0.0 8.8 0.0 8.5 0.5 10.2 19.2 0.0 17.4 0.0 0.4 2.0 25.5 0.1 3.9 0.0 18.2 38.4 0.0 0.1 0.0 33.2 31.5 0.2 1.4 54.9 10.3 0.4 0.0 25.8 0.0 2.8 22.3 5.8 3.7 13.5 0.0 0.4 5.7 0.9 11.8 0.0 4.7 0.1 0.0 13.1 4.2 0.0 0.1 3.3 0.5 1.7 1.7 35.5 3.0 0.5 5.6 5.5 6.1 6.0 1.1 7.0 5.8 5.0 36.6 7.4 0.3 2.5 7.4 2.1 18.3 25.5 14.4 20.2 15.5 17.0 12.0 19.9 13.3 12.2 20.3 24.7 38.2 6.4 8.2 0.3 21.3 8.9 6.9 3.2 5.7 48.4 4.1 6.9 9.5 4.3 5.9 25.8 50.1 7.0 7.0 33.4 3.9 2.6 4.5 21.6 6.3 33.8 3.5 5.7 13.2 1.2 1.8 7.5 11.2 45.3 0.0 1.2 42.8 0.6 16.0 11.8 17.8 12.1 8.2 44.5 23.4 7.6 0.3 20.9 3.6 7.5 4.3 16.1 3.1 43.2 40.6 2.3 8.3 1.9 4.0 3.0 36.6 1.1 4.5 122.6 6.6 1.6 3.5 0.6 0.5 1.0 6.7 63.1 21.4 10.4 1.1 9.1 ABHD10 FLJ11342 ENSG00000144827 "Abhydrolase domain containing 10, depalmitoylase" Q9NUJ1 3 111979010-111993368 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036991, HPA036992, HPA066081" Supported Approved Mitochondria "Intracellular and membrane" No No 71000 "Cluster 46: Basophils - DNA binding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA036991: AB_2675420, HPA036992: AB_10672345, HPA066081: AB_2685610" "unprognostic (1.65e-1)" "prognostic favorable (7.57e-4)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (1.14e-1)" "unprognostic (8.50e-2)" "unprognostic (1.69e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-2)" "prognostic favorable (4.72e-9)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (4.18e-3)" "unprognostic (2.76e-2)" 11.0 21.9 23.0 10.6 25.3 10.9 15.0 24.5 29.3 11.3 22.9 14.1 11.7 11.1 50.8 8.2 14.9 10.1 25.0 23.9 24.6 49.4 34.4 10.1 17.9 23.5 23.2 19.8 13.7 16.7 27.9 10.8 23.7 20.4 14.7 27.0 25.5 13.7 14.1 10.0 10.3 10.0 24.4 14.6 14.9 16.4 26.3 21.8 31.1 19.6 16.2 9.5 8.3 25.3 40.2 34.1 36.4 12.0 20.5 27.5 19.8 41.4 21.5 33.0 31.7 35.3 22.4 36.0 22.6 17.2 22.7 21.6 16.3 23.0 44.9 12.1 20.6 29.7 15.4 30.7 16.3 60.3 30.4 16.9 16.7 17.0 42.4 22.7 35.9 42.1 13.9 14.9 36.7 13.7 56.9 27.9 23.7 43.8 53.2 50.9 23.4 16.7 34.6 17.1 24.6 17.9 33.2 23.7 39.8 14.3 26.8 21.8 20.6 19.7 25.3 14.4 21.7 23.6 9.0 61.4 20.1 32.4 21.5 29.4 16.5 25.2 9.8 21.6 16.8 26.2 12.2 11.3 28.1 21.6 15.4 13.9 2.5 11.4 17.3 17.8 13.2 16.1 23.0 25.3 24.5 29.3 23.9 24.6 23.5 23.2 23.7 24.4 26.3 25.3 9.1 0.0 7.2 11.1 19.7 7.0 10.2 12.1 14.2 21.8 12.7 10.9 26.1 7.2 12.4 11.0 8.4 19.2 16.1 7.0 35.2 5.2 1.0 11.1 10.3 8.8 12.1 24.2 16.0 7.8 14.9 12.3 12.8 6.8 9.5 9.5 10.0 26.2 14.1 42.1 16.2 13.4 6.1 19.5 7.0 3.0 10.5 11.0 10.6 15.0 10.7 20.4 12.3 14.6 15.6 5.4 4.0 7.5 25.0 5.1 7.0 42.5 19.5 16.2 0.0 7.9 8.9 29.7 37.0 13.6 8.2 5.5 14.6 19.2 12.1 4.5 ABHD14A "DKFZP564O243, DORZ1" ENSG00000248487 "Abhydrolase domain containing 14A" Q9BUJ0 3 51971426-51981199 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 124.3;Rod photoreceptor cells: 115.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 79.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038153, HPA056913" Approved Enhanced Vesicles NA NA 420000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA038153: AB_2675868, HPA056913: AB_2683275" "unprognostic (4.15e-3)" "unprognostic (6.73e-2)" "unprognostic (1.98e-1)" "unprognostic (3.34e-2)" "unprognostic (2.71e-1)" "unprognostic (1.08e-2)" "unprognostic (8.92e-2)" "prognostic favorable (4.72e-4)" "unprognostic (3.96e-1)" "unprognostic (2.46e-2)" "unprognostic (5.52e-3)" "unprognostic (1.51e-2)" "unprognostic (1.97e-2)" "unprognostic (9.74e-2)" "unprognostic (2.17e-1)" "unprognostic (1.33e-1)" "unprognostic (1.30e-2)" 23.5 48.6 65.2 8.3 64.5 13.5 18.4 72.3 78.0 25.1 67.6 18.1 10.6 15.0 28.3 8.4 24.2 12.1 36.1 64.8 69.3 35.3 26.1 14.3 11.4 59.6 60.0 27.1 26.6 27.1 49.6 8.9 59.7 19.0 6.9 43.5 23.2 14.5 34.8 7.6 12.9 7.5 59.2 14.6 17.7 13.2 69.4 11.5 32.8 39.1 8.4 19.4 16.7 59.8 6.9 12.9 8.2 24.7 79.8 39.9 4.5 9.0 14.8 10.6 14.3 14.8 27.0 7.8 6.0 22.4 12.1 6.2 9.0 10.0 3.4 25.1 10.0 22.7 37.4 50.0 22.4 31.4 29.0 37.9 6.6 9.0 4.6 23.7 13.8 14.6 9.3 25.4 16.8 7.8 14.5 31.8 4.7 32.4 30.4 10.3 4.2 73.9 20.7 10.6 16.8 26.1 22.5 4.7 13.5 1.7 7.1 33.7 8.2 9.6 10.4 23.4 10.7 37.0 37.4 6.6 18.1 49.6 14.1 6.9 20.3 15.2 94.0 12.7 96.5 49.0 80.9 83.5 36.2 41.5 73.7 79.0 2.1 45.5 8.6 46.0 88.4 54.9 65.2 64.5 72.3 78.0 64.8 69.3 59.6 60.0 59.7 59.2 69.4 59.8 15.9 6.4 21.7 0.0 20.2 9.7 25.1 29.0 4.0 90.8 21.0 22.9 24.3 20.0 20.8 33.1 25.0 10.3 29.6 7.1 33.2 15.5 4.7 23.5 18.0 14.1 40.2 2.5 0.0 12.4 15.3 36.9 4.6 14.9 15.2 12.8 17.2 16.2 29.3 58.9 0.0 14.0 24.4 14.2 18.5 24.9 88.0 14.6 12.4 0.0 7.4 59.9 41.2 0.0 0.0 17.1 5.6 33.1 16.3 17.0 13.8 124.3 29.5 115.2 19.7 24.7 16.8 18.2 57.8 1.8 5.5 4.9 28.9 20.6 15.3 19.5 ABHD14A-ACY1 ENSG00000114786 "ABHD14A-ACY1 readthrough" 3 51974706-51989183 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 4.8;Collecting duct cells: 5.5;Distal tubular cells: 3.9;Proximal tubular cells: 16.8;Theca cells: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA036174, HPA036175, HPA038153" Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA036174: AB_2674988, HPA036175: AB_2674989, HPA038153: AB_2675868" "unprognostic (8.40e-2)" "unprognostic (1.37e-1)" "unprognostic (4.90e-2)" "unprognostic (7.22e-3)" "unprognostic (3.83e-2)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.35e-1)" "unprognostic (6.23e-2)" "unprognostic (2.71e-1)" "unprognostic (1.10e-1)" "unprognostic (1.29e-2)" "unprognostic (9.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (7.11e-4)" 0.5 0.8 0.1 0.1 0.1 0.0 0.4 0.6 0.4 0.2 0.2 0.2 0.0 0.6 0.0 0.2 0.5 0.1 0.2 0.1 0.2 0.3 0.3 0.2 0.0 0.2 0.1 0.1 0.3 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.4 0.0 0.7 0.2 0.2 0.0 0.2 0.2 0.4 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.4 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.4 0.5 1.2 0.9 0.8 0.6 0.7 1.1 1.0 0.5 0.7 1.0 0.0 1.1 0.6 0.6 1.0 0.5 0.1 0.1 0.6 0.4 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.2 1.4 0.0 4.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 3.2 3.2 0.0 0.0 1.8 5.5 0.0 0.0 0.9 0.1 3.9 1.5 0.0 0.4 1.4 0.6 0.0 0.8 1.0 1.2 0.0 1.0 2.0 0.8 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.5 1.2 2.0 0.0 0.0 0.0 0.0 0.2 16.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 6.3 0.0 0.0 ABHD15 ENSG00000168792 "Abhydrolase domain containing 15" Q6UXT9 17 29560547-29567037 "Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 26.2" "Cell type enhanced" "Detected in many" "dendritic cells: 79.4;Hepatocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.3;MAIT T-cell: 6.6;NK-cell: 10.8;plasmacytoid DC: 23.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA014470 Approved Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "HPA014470: AB_1852993" "unprognostic (1.79e-1)" "unprognostic (4.00e-2)" "unprognostic (1.38e-1)" "unprognostic (8.60e-3)" "unprognostic (1.91e-1)" "unprognostic (1.62e-1)" "unprognostic (4.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.85e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-3)" "unprognostic (3.00e-2)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (1.71e-1)" "unprognostic (3.46e-1)" "unprognostic (5.45e-2)" 19.2 3.8 3.6 6.2 4.0 8.2 10.6 3.8 3.3 4.6 3.8 7.3 11.2 4.5 3.3 4.7 4.7 5.2 4.9 3.1 4.1 8.9 26.2 6.0 9.1 4.9 4.2 2.9 8.1 7.9 9.1 4.5 4.7 4.7 6.5 1.6 5.1 3.8 2.6 4.6 11.2 4.0 4.2 9.9 8.3 1.8 4.3 4.6 5.8 3.8 8.1 5.6 4.6 4.9 5.8 22.1 2.7 7.7 29.0 12.6 11.3 7.8 8.6 7.6 6.9 5.1 2.9 8.6 5.6 8.4 13.4 15.6 9.7 3.3 4.2 26.5 7.3 3.5 11.0 6.5 8.8 9.0 15.4 9.4 8.9 7.3 1.4 5.6 5.6 5.0 4.6 8.0 4.1 7.8 8.5 10.4 0.6 19.5 6.5 19.7 10.5 20.0 13.7 8.8 1.9 3.1 11.7 5.2 3.1 2.9 13.2 20.5 6.9 4.4 5.5 11.1 7.0 13.3 9.6 4.4 8.8 5.6 9.6 18.3 0.6 2.8 2.6 0.3 6.6 1.4 1.4 2.2 1.5 2.5 0.4 1.3 0.6 10.8 0.2 23.6 1.2 1.1 3.6 4.0 3.8 3.3 3.1 4.1 4.9 4.2 4.7 4.2 4.3 4.9 2.4 3.2 4.1 2.6 11.7 1.3 1.1 2.5 2.2 0.1 3.8 2.4 3.0 2.8 4.3 7.3 0.0 1.5 79.4 12.0 0.0 3.0 0.3 4.7 3.1 2.9 7.2 7.0 0.3 7.6 1.4 4.0 2.0 5.1 2.5 2.9 4.2 30.2 7.2 1.7 0.5 6.1 2.0 6.7 8.4 0.7 4.7 9.5 5.4 2.8 5.6 1.1 15.5 0.5 1.2 5.6 2.5 4.5 5.2 1.5 17.7 5.6 5.2 0.9 0.0 3.5 1.9 0.8 0.6 2.0 2.4 0.3 11.8 4.5 7.4 1.2 ABHD8 "FLJ11743, MGC14280, MGC2512" ENSG00000127220 "Abhydrolase domain containing 8" Q96I13 19 17292131-17310236 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 57.8" "Cell type enhanced" "Detected in many" "Early spermatids: 146.2;Horizontal cells: 72.3;Late spermatids: 314.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 53.9;U-266/70: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037658, HPA058209" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA037658: AB_10672602, HPA058209: AB_2683638" "unprognostic (4.71e-3)" "unprognostic (5.06e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (7.45e-3)" "unprognostic (7.09e-2)" "unprognostic (1.96e-2)" "unprognostic (5.61e-2)" "unprognostic (9.62e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.04e-5)" "unprognostic (3.77e-1)" "unprognostic (6.36e-3)" "unprognostic (1.56e-1)" "unprognostic (3.14e-1)" "unprognostic (1.50e-1)" "unprognostic (9.24e-2)" 7.4 26.0 32.3 3.9 37.2 4.5 8.8 20.6 57.8 12.0 14.3 16.7 2.7 11.5 1.7 5.7 11.2 2.9 12.4 36.3 23.8 11.6 28.2 9.6 4.5 19.2 26.5 14.2 11.6 8.9 24.6 5.6 19.5 14.6 0.6 6.1 10.5 6.7 13.8 11.3 7.8 2.7 16.1 11.4 11.1 45.7 30.0 4.7 12.1 3.9 2.2 10.2 8.8 27.0 22.5 6.4 3.2 12.6 4.1 1.4 34.2 4.5 6.0 4.8 6.1 5.6 15.0 1.6 6.1 3.5 7.4 3.1 3.2 7.8 1.0 26.6 21.1 7.3 9.6 9.7 13.4 0.5 9.9 3.8 4.7 8.2 1.0 7.4 3.5 12.5 6.6 12.4 1.9 1.2 9.0 1.3 6.0 3.8 53.9 13.3 9.9 6.5 4.3 2.1 3.9 21.3 10.0 3.3 14.6 2.8 13.6 12.6 2.1 4.4 9.6 22.7 8.1 40.6 33.0 7.9 14.9 8.7 4.1 0.0 2.4 3.0 1.1 1.9 0.7 0.3 1.6 0.9 2.9 0.5 1.3 1.2 1.3 1.7 1.9 1.3 1.2 1.0 32.3 37.2 20.6 57.8 36.3 23.8 19.2 26.5 19.5 16.1 30.0 27.0 5.9 0.0 1.3 20.9 5.0 3.8 4.7 8.0 8.6 56.9 9.6 14.4 2.0 7.2 4.8 7.3 18.8 20.6 4.0 0.8 7.9 13.1 146.2 3.0 3.7 4.3 7.2 0.8 22.7 8.5 9.0 7.7 2.6 2.5 4.5 12.3 4.2 13.5 22.5 72.3 19.4 3.3 12.2 8.1 6.9 314.2 12.5 11.1 1.8 8.4 18.4 36.1 7.2 2.5 1.4 8.4 4.3 25.6 9.2 6.3 0.4 9.7 1.7 38.2 6.6 13.6 5.6 64.3 1.5 3.0 4.1 24.8 4.8 10.8 1.3 4.3 ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Fibroblasts: 213.8;Leydig cells: 97.3;Muller glia cells: 93.7;Skeletal myocytes: 106.8" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 437.3;hTEC/SVTERT24-B: 840.8;hTERT-HME1: 818.4;TIME: 1405.8;U-2197: 311.0" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" NA NA 550000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" 41.3 9.9 3.9 57.0 9.7 0.2 23.1 0.8 4.1 56.4 3.1 36.5 5.3 49.5 10.7 35.1 46.9 97.9 44.5 3.8 26.6 12.2 7.8 68.7 25.9 3.4 5.7 89.4 12.7 3.0 4.7 51.9 7.3 8.7 56.2 57.5 13.7 12.3 6.7 14.0 15.4 72.0 5.6 12.4 25.5 17.1 6.7 7.9 25.0 41.1 39.9 96.7 23.7 9.1 1.3 0.3 0.1 0.0 37.0 437.3 0.4 91.9 90.2 171.4 79.9 0.0 0.2 0.9 0.4 25.0 0.3 0.0 0.1 1.0 278.2 0.8 0.7 2.4 1.6 0.0 23.7 0.5 0.1 26.6 1.0 840.8 818.4 3.6 267.1 0.0 0.5 1.3 158.6 0.0 0.5 0.3 0.1 0.0 87.5 0.4 0.7 0.7 54.0 0.2 0.2 0.6 0.0 0.6 0.1 0.8 0.3 0.1 1405.8 37.7 0.4 311.0 19.7 1.0 0.0 0.0 43.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 9.7 0.8 4.1 3.8 26.6 3.4 5.7 7.3 5.6 6.7 9.1 9.1 57.7 5.5 26.1 0.3 15.9 1.5 5.8 4.6 1.2 0.6 1.8 9.7 10.0 39.8 18.4 2.1 0.5 0.1 0.4 0.0 0.3 10.3 1.2 30.6 23.6 1.2 0.0 2.6 0.4 0.4 213.8 9.7 2.4 3.8 0.2 16.1 0.1 0.9 0.0 47.0 0.8 0.0 0.6 23.2 8.8 97.3 1.8 19.6 7.5 0.0 93.7 0.0 1.5 3.3 1.9 5.4 27.8 0.7 1.5 0.2 9.0 5.0 3.7 0.0 106.8 17.5 0.1 0.3 3.9 19.9 0.7 2.1 3.6 1.0 2.9 ABITRAM "C9orf6, CG-8, FAM206A, FLJ20457, Simiate" ENSG00000119328 "Actin binding transcription modulator" Q9NX38 9 108934400-108950744 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 20.7;Cytotrophoblasts: 6.0;Extravillous trophoblasts: 10.6;Fibroblasts: 4.3;Hofbauer cells: 7.8;Syncytiotrophoblasts: 7.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035917, HPA035918" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA No "Cluster 31: Non-specific - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA035917: AB_2674860, HPA035918: AB_10670593" "unprognostic (4.89e-2)" "unprognostic (2.62e-1)" "unprognostic (1.85e-1)" "unprognostic (4.00e-3)" "unprognostic (1.05e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-3)" "unprognostic (1.10e-2)" "unprognostic (1.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.16e-2)" "unprognostic (3.50e-2)" "unprognostic (1.57e-2)" "unprognostic (3.25e-2)" "unprognostic (2.03e-1)" "unprognostic (2.28e-1)" "unprognostic (1.62e-1)" 14.2 11.9 17.2 10.0 18.7 15.6 17.2 16.8 21.9 12.5 18.7 14.9 14.4 13.6 25.1 16.4 21.5 10.9 15.8 17.7 17.3 13.6 14.6 12.7 9.0 16.8 17.1 13.5 13.3 23.2 13.9 12.5 17.2 12.1 16.2 24.7 15.3 14.2 13.2 24.5 13.1 12.5 17.5 8.5 14.5 20.2 17.5 11.9 19.0 11.8 12.0 11.9 11.4 18.3 18.5 19.8 19.5 23.4 36.2 44.6 28.1 17.1 20.0 17.0 13.9 29.5 9.7 17.0 9.8 16.6 22.3 41.3 17.2 18.3 16.0 10.4 17.6 10.5 25.8 27.0 30.7 40.4 13.3 25.3 33.6 20.7 47.6 20.9 23.7 26.1 39.7 16.6 20.3 53.0 28.9 16.3 22.6 55.9 28.7 13.9 33.9 18.9 22.5 19.2 26.7 13.7 27.0 23.3 30.1 20.0 31.6 21.4 14.9 9.2 16.9 39.3 21.7 14.7 38.5 12.6 30.1 15.6 13.4 38.8 31.2 31.0 14.8 33.4 22.6 16.5 23.1 19.6 35.5 10.8 22.9 17.6 37.4 21.1 34.6 37.0 21.1 20.1 17.2 18.7 16.8 21.9 17.7 17.3 16.8 17.1 17.2 17.5 17.5 18.3 2.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.7 0.0 0.0 0.0 0.0 6.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 10.6 4.3 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 7.3 0.3 0.0 0.0 0.0 ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099330-179229684 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 166.8;Langerhans cells: 188.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "hTERT-HME1: 73.5;TIME: 70.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "CAB017106: , HPA001866: AB_1078082, HPA072754: AB_2732212" "unprognostic (3.05e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (9.45e-2)" "unprognostic (8.23e-3)" "unprognostic (1.91e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-1)" "unprognostic (6.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (8.40e-4)" 9.3 3.2 5.9 4.9 6.7 2.7 5.7 6.1 6.1 5.4 2.0 4.6 2.8 3.7 2.7 2.5 3.2 11.8 3.9 7.4 5.0 3.6 2.7 6.5 2.7 3.8 4.4 3.5 5.7 4.2 3.8 4.1 3.9 3.5 3.3 9.2 3.5 2.6 3.1 4.2 3.2 4.5 3.0 2.7 3.7 4.4 5.6 4.1 3.8 4.2 2.5 6.4 4.0 4.8 24.2 13.1 8.7 5.8 7.3 16.8 5.3 26.3 21.6 31.9 23.1 9.9 7.2 13.7 18.9 19.2 21.7 11.0 12.6 9.1 44.6 8.5 11.4 6.7 12.4 4.9 13.3 7.5 2.1 15.6 11.6 45.3 73.5 13.9 36.2 7.0 16.1 3.8 42.6 6.5 5.9 4.0 8.3 5.0 4.3 8.6 14.4 6.5 10.8 4.0 5.2 11.9 22.0 7.0 53.8 13.2 6.2 6.4 70.7 33.3 24.5 15.7 42.8 7.0 9.3 14.1 15.6 4.0 32.4 1.4 0.3 0.0 0.5 0.1 0.2 0.5 0.3 0.3 0.2 0.7 0.4 0.5 0.6 0.5 0.1 0.5 0.2 0.1 5.9 6.7 6.1 6.1 7.4 5.0 3.8 4.4 3.9 3.0 5.6 4.8 33.5 22.4 24.0 44.1 14.4 46.9 43.6 16.3 12.5 40.0 18.7 9.5 8.9 22.8 10.8 11.0 166.8 9.3 7.7 15.5 11.7 14.3 15.6 12.3 23.4 67.2 27.0 9.9 81.6 13.9 8.2 67.6 10.2 21.5 17.1 19.5 31.1 15.3 22.9 25.2 62.0 11.0 10.2 34.9 188.1 32.2 15.2 67.7 69.4 45.0 13.9 11.3 8.2 72.4 57.1 45.5 16.0 13.5 10.3 42.6 9.9 9.4 11.0 35.7 6.6 32.3 30.5 17.8 30.5 11.5 38.4 10.4 12.4 11.6 14.9 25.3 ABRAXAS1 "ABRA1, ABRAXAS, CCDC98, FAM175A, FLJ13614" ENSG00000163322 "Abraxas 1, BRCA1 A complex subunit" Q6UWZ7 4 83459517-83523348 "Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 43.0;Endometrial stromal cells: 20.7;Proximal tubular cells: 30.1;Respiratory ciliated cells: 21.9;Theca cells: 26.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 36.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037654 Uncertain Supported "Nuclear bodies" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" "Nuclear bodies" "HPA037654: AB_2675588" "unprognostic (1.44e-1)" "unprognostic (2.46e-2)" "unprognostic (2.42e-2)" "unprognostic (1.81e-1)" "unprognostic (8.57e-3)" "unprognostic (6.99e-2)" "unprognostic (4.98e-4)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (2.73e-1)" "unprognostic (2.35e-1)" "unprognostic (6.98e-2)" "prognostic favorable (1.53e-4)" "unprognostic (2.24e-3)" "unprognostic (9.34e-3)" "unprognostic (5.58e-2)" "unprognostic (6.57e-2)" 4.4 3.9 2.9 3.9 2.0 7.9 3.8 7.7 3.0 5.1 12.0 3.3 3.7 6.4 2.1 5.2 4.8 5.7 3.7 2.4 1.4 4.1 2.2 3.8 8.0 2.2 2.2 14.8 3.4 2.2 1.1 2.9 2.4 2.7 2.8 3.6 3.5 2.2 6.4 5.7 3.1 2.9 0.5 4.1 3.6 10.8 2.6 4.8 7.4 2.0 3.8 3.8 3.5 5.1 5.6 3.4 6.8 8.2 6.1 25.2 3.6 4.1 5.1 1.9 2.9 7.6 9.0 22.1 3.3 4.3 4.2 2.9 3.7 2.9 3.5 8.8 2.4 12.9 4.6 9.1 4.9 15.3 11.1 10.9 2.5 2.7 2.4 10.2 8.7 12.9 36.7 13.2 4.7 3.7 17.2 5.6 11.5 6.3 5.0 9.3 7.6 5.5 4.2 4.6 6.3 5.1 5.3 2.2 9.6 5.5 6.3 6.3 11.5 7.4 7.6 7.4 6.0 11.5 8.4 16.1 6.7 12.8 5.3 4.0 2.5 2.1 2.0 2.3 2.6 2.1 3.5 2.4 1.9 3.3 5.4 4.2 3.2 5.0 2.3 1.5 3.2 1.9 2.9 2.0 7.7 3.0 2.4 1.4 2.2 2.2 2.4 0.5 2.6 5.1 14.3 16.0 12.4 0.0 4.6 0.0 0.0 0.0 0.0 0.0 11.4 13.0 0.0 0.0 8.6 12.9 0.0 5.2 8.8 0.0 43.0 9.2 0.0 11.9 20.7 5.7 0.0 0.0 0.0 6.5 6.9 9.1 0.0 5.9 6.3 12.3 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 7.2 0.0 0.0 0.0 0.0 7.4 0.0 0.0 1.7 0.0 0.0 30.1 21.9 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 2.9 6.2 26.8 0.0 0.0 ABRAXAS2 "ABRO1, Em:AC068896.4, FAM175B, KIAA0157" ENSG00000165660 "Abraxas 2, BRISC complex subunit" Q15018 10 124801819-124836667 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Collecting duct cells: 23.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037591, HPA037592, HPA074089" Approved Supported Cytosol Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA037591: AB_10671877, HPA037592: AB_2675566, HPA074089: AB_2686659" "unprognostic (2.78e-1)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (6.47e-2)" "unprognostic (1.08e-1)" "unprognostic (3.51e-2)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.99e-1)" "unprognostic (6.81e-2)" "unprognostic (3.72e-2)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.09e-2)" "unprognostic (1.58e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" 9.1 10.5 8.0 10.3 8.3 12.3 12.2 8.0 9.9 8.8 6.6 9.9 10.2 9.4 9.3 9.8 9.0 8.2 10.0 8.4 8.6 12.3 13.7 9.3 12.5 7.8 8.4 10.4 8.3 12.7 3.9 10.3 8.5 9.5 10.3 5.3 8.5 8.8 19.0 11.6 10.8 10.5 7.7 10.0 9.5 6.7 8.2 12.9 12.7 16.2 13.3 9.7 6.8 7.9 22.2 14.9 15.7 21.6 19.9 19.6 13.5 22.4 35.1 26.2 24.1 12.1 20.9 24.7 18.6 24.4 14.2 24.4 25.0 21.0 27.5 21.6 17.2 18.8 11.8 15.0 25.4 32.6 18.9 21.6 25.1 25.8 46.4 28.3 20.1 21.7 20.0 16.6 21.6 14.5 25.1 29.1 13.5 20.0 13.8 20.0 16.6 15.1 19.5 11.1 10.8 19.8 17.9 17.0 24.4 15.8 14.0 22.2 17.4 14.0 11.2 16.5 27.1 17.2 17.1 23.6 18.3 15.9 10.1 22.8 10.5 9.8 7.6 14.5 10.5 10.5 8.8 10.6 12.9 11.6 9.3 10.3 4.1 7.7 11.8 8.7 11.4 7.0 8.0 8.3 8.0 9.9 8.4 8.6 7.8 8.4 8.5 7.7 8.2 7.9 15.1 25.6 14.3 0.0 3.5 0.0 0.0 0.0 0.0 0.0 9.4 10.3 0.0 0.0 6.2 23.9 0.0 16.9 7.0 0.0 17.6 13.7 0.0 11.1 15.6 6.3 0.0 0.0 0.0 12.5 13.0 5.5 0.0 12.3 12.6 12.4 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 20.7 0.0 0.0 0.0 0.0 10.2 0.0 0.0 1.6 0.0 0.0 18.6 12.4 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 16.0 4.3 13.5 0.0 0.0 AC001226.2 ENSG00000283208 "Novel protein" 13 76992078-77129589 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 4.4;brain: 3.2" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.6;Glandular and luminal cells: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 6: Brain - Smell perception" "Cluster 44: Endometrium - Transcription" 1.1 0.2 1.0 0.3 1.3 4.4 0.8 3.2 2.1 0.7 0.0 0.3 0.0 0.3 0.6 0.3 0.3 0.3 0.5 1.3 0.1 0.3 0.2 0.5 0.4 0.0 0.0 0.6 0.4 0.0 0.3 0.1 0.1 0.2 0.0 1.8 0.3 0.3 0.6 1.7 0.3 0.1 0.1 0.3 0.2 0.3 0.0 0.1 0.5 0.2 0.0 0.4 0.6 0.6 0.2 0.1 0.3 0.0 0.5 0.2 0.2 0.0 0.2 0.1 0.0 0.0 0.3 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.9 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.4 0.1 0.0 0.2 0.8 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.2 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.7 0.1 0.5 0.1 0.9 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.2 0.0 0.5 0.2 0.2 0.2 0.1 0.6 0.1 0.2 0.0 1.0 1.3 3.2 2.1 1.3 0.1 0.0 0.0 0.1 0.1 0.0 0.6 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 1.6 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 AC007846.2 ENSG00000285471 "Novel protein" 17 5772926-6080792 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "RH-30: 38.2" NA NA "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.9 0.2 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.0 38.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.1 0.1 0.3 0.3 0.6 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC008687.1 ENSG00000267335 "Novel protein" 19 49022953-49036895 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "pituitary gland: 17.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.6;HMC-1: 4.4;U-138 MG: 1.6;U-251 MG: 6.0" HPA038925 Uncertain Approved Cytosol "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" Cytosol "HPA038925: AB_2676272" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.7 0.0 17.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.6 0.1 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.6 0.0 0.2 0.0 0.0 1.6 1.3 0.3 6.0 0.3 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 AC025165.3 ENSG00000257921 "Novel protein" 12 57772660-57797554 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "glioma: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.2;RH-30: 1.6" NA NA "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (2.84e-1)" "unprognostic (2.88e-1)" "unprognostic (1.38e-4)" "unprognostic (3.74e-2)" "unprognostic (6.78e-4)" "unprognostic (2.19e-2)" "unprognostic (2.05e-1)" "unprognostic (8.27e-2)" "unprognostic (4.63e-2)" "unprognostic (2.55e-1)" "unprognostic (3.46e-2)" "unprognostic (6.73e-2)" "unprognostic (1.74e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC073896.1 ENSG00000144785 "Novel protein" 12 56285916-56316059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 18.8;salivary gland: 19.4" "Cell type enhanced" "Detected in single" "Club cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA038466, HPA068007" Uncertain Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 4: Stomach - Digestion" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Centriolar satellite" "HPA038466: AB_10672646, HPA068007: " "unprognostic (3.07e-2)" "unprognostic (9.89e-3)" "unprognostic (8.23e-2)" "unprognostic (3.45e-2)" "unprognostic (8.20e-3)" "unprognostic (1.63e-1)" "unprognostic (2.13e-1)" "unprognostic (1.38e-1)" "unprognostic (3.74e-3)" "unprognostic (2.83e-1)" "unprognostic (1.04e-1)" "unprognostic (9.26e-4)" "unprognostic (2.22e-1)" "unprognostic (3.01e-1)" "unprognostic (1.93e-1)" 7.0 5.7 1.5 3.5 1.5 5.1 3.9 1.5 5.3 1.7 2.6 8.9 9.8 1.2 0.3 3.0 3.3 5.9 1.4 1.7 1.2 3.0 4.7 1.8 2.2 1.6 1.4 3.7 18.8 3.7 0.3 4.4 1.6 2.5 0.3 0.7 19.4 6.6 1.5 1.0 5.6 0.9 1.3 4.2 7.0 2.0 1.6 3.3 3.3 1.4 0.9 2.6 0.3 2.2 22.0 38.1 5.4 23.4 17.4 12.6 37.7 42.5 42.1 33.2 23.4 43.2 22.7 15.8 61.9 17.7 18.8 49.0 9.9 15.3 3.8 30.6 18.4 0.8 22.8 42.6 37.6 15.5 45.4 24.5 23.3 18.3 1.1 19.8 29.0 43.8 19.2 18.5 5.1 36.9 11.0 24.7 37.5 19.1 97.7 50.3 21.2 29.2 0.3 3.4 30.6 29.1 26.1 25.8 26.9 0.6 20.9 84.8 20.6 30.1 15.6 18.8 37.4 29.4 62.0 17.1 41.4 27.0 41.3 31.5 41.3 19.4 40.8 36.4 41.6 65.1 35.5 43.2 50.3 51.9 40.9 38.7 6.9 41.7 22.1 59.5 39.6 70.1 1.5 1.5 1.5 5.3 1.7 1.2 1.6 1.4 1.6 1.3 1.6 2.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 AC079741.2 ENSG00000288634 "Novel protein" 7 112450487-112450645 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "bone marrow: 27.0;brain: 9.8;skeletal muscle: 7.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 18.6;SiHa: 19.4;U-2197: 19.1;U-266/70: 14.6;U-937: 20.3;WM-115: 27.5" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" 0.3 0.0 3.4 0.5 5.3 27.0 0.0 1.6 6.4 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 4.1 0.1 0.5 0.7 0.1 4.3 3.1 0.4 0.0 0.0 0.2 3.6 0.0 0.0 0.8 0.6 0.0 7.5 0.0 1.0 0.0 1.8 1.2 1.4 0.0 3.1 0.1 0.0 0.0 0.0 0.0 9.8 1.5 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 8.4 13.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 13.5 0.0 0.0 18.6 0.0 12.8 1.3 0.0 8.0 0.0 0.0 0.0 0.0 1.0 0.0 19.4 3.0 0.0 0.0 0.0 0.0 2.9 11.1 10.4 19.1 6.3 14.6 1.0 5.0 0.6 20.3 27.5 8.2 4.2 15.2 3.3 3.8 2.1 7.8 3.5 3.6 3.0 5.6 2.6 1.8 18.0 2.3 2.3 0.9 4.1 1.6 3.4 5.3 1.6 6.4 3.5 4.1 4.3 3.1 3.6 1.8 3.1 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC083977.1 ENSG00000286131 "Novel protein" 8 32647202-32647390 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 1.2 0.1 0.0 1.0 0.0 1.2 0.3 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC090527.2 ENSG00000260170 "Novel protein" 15 45587351-45676314 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "neutrophil: 6.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HBEC3-KT: 1.3;THP-1: 1.1" HPA041589 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA041589: AB_2677565" "unprognostic (5.93e-2)" "unprognostic (1.18e-1)" "unprognostic (2.03e-2)" "unprognostic (1.54e-1)" 0.1 0.0 0.1 0.0 0.2 0.4 0.1 0.0 0.2 0.0 0.2 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 1.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.7 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.3 0.2 2.2 1.7 0.9 0.8 0.8 1.0 0.7 0.7 0.3 0.0 1.3 1.6 0.4 6.2 0.0 0.9 0.5 1.2 0.4 0.1 0.2 0.0 0.2 0.2 0.1 0.1 0.2 0.2 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC092442.1 ENSG00000284684 "Novel protein" 4 6064977-6070162 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 16 "brain: 6.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "amygdala: 1.8;basal ganglia: 6.0;cerebral cortex: 3.7;hippocampal formation: 1.9;hypothalamus: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" 0.0 0.0 1.8 0.0 6.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 6.0 0.0 3.7 1.9 2.4 0.1 0.1 0.3 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC092718.7 ENSG00000284512 "Novel protein" 16 81022316-81096284 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9;testis: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" HPA041368 Uncertain Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" Vesicles "HPA041368: AB_10804001" 0.1 0.2 2.7 0.3 3.5 1.1 0.2 2.9 3.5 0.2 2.1 0.1 0.1 0.3 0.2 0.1 0.2 0.1 0.1 2.4 2.5 0.2 0.2 0.1 0.2 2.9 3.0 0.3 0.2 0.3 0.3 0.2 2.8 1.3 0.0 0.7 0.1 0.1 0.1 0.2 0.1 0.0 2.7 0.1 0.1 6.5 2.8 0.0 0.5 0.0 0.0 0.1 0.1 3.9 0.4 0.2 0.6 0.5 0.1 0.0 0.5 0.8 0.1 0.1 0.0 0.4 0.6 0.6 0.3 0.2 0.3 0.9 0.0 0.0 0.1 0.1 0.4 0.3 1.0 0.6 0.0 0.6 1.1 0.2 0.0 0.1 0.0 0.3 0.0 0.7 0.3 1.0 0.0 1.3 0.6 1.4 0.6 0.2 0.4 0.5 0.4 0.1 0.0 0.3 0.9 0.2 0.6 0.3 0.1 0.3 0.4 0.2 0.1 0.5 0.6 0.4 0.3 0.5 0.3 1.2 0.2 0.3 0.2 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.3 0.1 0.2 0.2 0.2 0.1 0.4 0.3 0.1 2.7 3.5 2.9 3.5 2.4 2.5 2.9 3.0 2.8 2.7 2.8 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC093525.1 ENSG00000259784 "Novel protein" 16 2513965-2527955 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.9;brain: 1.6;intestine: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 1.5;REH: 1.4;THP-1: 1.4;U-266/70: 2.0" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 29: U-266 - Adaptive immune response" 0.2 0.1 0.3 0.0 0.5 1.9 0.0 0.5 1.6 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.4 0.0 0.2 0.2 0.7 0.4 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.1 0.2 0.1 1.1 0.3 0.1 0.2 0.5 0.1 1.2 0.0 0.1 0.0 0.0 0.1 0.1 0.9 0.5 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.2 0.7 0.0 0.4 0.0 0.3 0.0 0.2 0.5 0.0 1.5 0.0 0.0 1.1 0.0 0.4 0.0 0.3 0.0 0.5 0.4 0.0 1.0 0.0 0.0 0.3 0.3 0.2 0.4 0.0 0.5 0.0 0.4 0.2 0.0 0.3 1.4 0.4 0.5 0.0 0.0 0.4 0.1 0.0 0.7 0.1 0.1 0.4 1.4 0.0 0.4 0.1 0.2 0.4 2.0 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.5 0.5 1.6 0.3 0.3 0.7 0.4 0.6 0.1 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC099489.1 ENSG00000188897 "Novel lipoprotein amino terminal region containing protein" 16 11359845-11527245 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 5.3;Glandular and luminal cells: 2.3;granulocytes: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 12 "neutrophil: 3.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.5" "Cell line enhanced" "Detected in some" "Daudi: 3.1;HDLM-2: 3.4;U-266/70: 1.7" "Not detected" "Not detected" HPA042154 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA042154: AB_2677877" "unprognostic (4.69e-2)" "unprognostic (3.80e-2)" "unprognostic (7.24e-2)" "unprognostic (5.91e-2)" "unprognostic (1.21e-3)" "unprognostic (7.91e-2)" "unprognostic (9.18e-2)" "unprognostic (6.08e-2)" "unprognostic (8.04e-2)" "unprognostic (5.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.04e-1)" "unprognostic (3.72e-6)" "unprognostic (3.18e-1)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (4.33e-5)" 2.2 0.5 0.7 3.7 0.6 1.5 0.9 0.8 1.7 1.7 0.6 0.8 0.1 0.9 0.3 0.5 3.4 0.5 1.4 0.6 0.4 2.2 2.3 5.2 0.8 0.6 0.5 0.7 0.8 0.5 1.0 0.3 1.0 1.9 0.1 0.2 3.0 0.4 2.4 3.6 1.0 0.1 0.4 18.6 1.2 4.8 0.5 0.2 0.9 0.4 0.3 1.6 1.1 0.9 0.0 0.4 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 3.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.0 0.1 0.1 1.0 0.3 0.0 0.0 0.2 0.1 1.1 0.0 0.2 0.3 0.2 0.0 0.4 0.4 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.7 0.1 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 3.5 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.8 1.7 0.6 0.4 0.6 0.5 1.0 0.4 0.5 0.9 0.4 9.6 5.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 1.5 0.0 0.0 1.3 0.0 0.0 0.1 1.0 0.0 0.0 0.5 0.0 1.6 0.9 0.3 0.0 0.0 0.0 0.2 0.1 0.5 0.0 2.3 3.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 AC109583.1 ENSG00000206549 "Novel protein identical to PRSS50" 3 46712115-46812574 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 4.8;thyroid gland: 6.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA040768 Supported NA NA "Cluster 51: Non-specific - Unknown function" "HPA040768: AB_2677126" "unprognostic (1.19e-2)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (7.59e-3)" "unprognostic (4.32e-1)" "unprognostic (7.45e-2)" "unprognostic (9.24e-2)" "unprognostic (1.37e-1)" "unprognostic (6.77e-2)" "unprognostic (2.23e-1)" "unprognostic (8.91e-4)" "unprognostic (1.08e-1)" "unprognostic (1.46e-3)" "unprognostic (2.68e-2)" "unprognostic (1.79e-2)" "unprognostic (9.36e-2)" "unprognostic (3.66e-3)" 0.2 0.3 0.1 0.0 0.1 0.0 0.7 0.7 0.2 1.7 0.5 0.5 0.1 0.7 3.0 0.1 1.0 0.0 1.5 0.0 0.4 1.6 0.8 0.3 0.0 0.3 0.3 0.7 1.5 1.8 4.6 0.0 0.3 1.5 0.0 0.1 0.8 0.7 4.8 0.2 0.2 0.1 0.2 0.1 0.3 1.8 0.3 0.0 6.0 0.2 0.0 0.6 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.2 0.0 0.4 0.3 0.3 0.3 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC114402.2 ENSG00000288644 "Novel protein" 1 203802094-203802192 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 2.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "cerebral cortex: 2.9;pons: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "U-698: 7.6" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC114490.2 ENSG00000284773 "Novel protein" 1 34974356-34985313 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 6 "Ductal cells: 14.3;Exocrine glandular cells: 7.4;monocytes: 5.2;Pancreatic endocrine cells: 9.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" 1.0 0.5 0.6 0.9 0.6 0.9 1.0 0.9 0.9 0.5 0.3 0.6 0.7 1.6 1.3 0.2 1.0 0.7 0.3 0.5 0.7 0.5 0.4 1.1 1.7 0.5 0.4 1.1 0.3 0.4 0.4 0.5 0.6 0.8 1.0 0.5 0.8 0.5 1.1 1.0 0.8 0.2 1.5 0.4 0.8 0.7 0.7 0.5 0.2 1.1 0.3 0.7 0.2 0.2 0.2 0.3 0.8 1.6 0.1 0.4 1.6 0.2 0.2 0.0 1.0 0.5 0.2 0.5 0.1 0.6 0.1 0.2 0.1 0.9 0.2 0.4 0.3 0.2 1.4 0.7 1.2 1.3 0.5 0.2 0.9 0.8 0.4 1.3 0.1 0.9 0.5 0.3 0.3 0.7 0.3 0.0 0.0 0.6 0.0 0.0 0.4 0.5 0.2 0.5 0.4 0.0 0.1 0.4 0.0 0.5 0.7 0.3 0.3 0.5 0.2 0.9 0.2 0.1 0.3 0.6 0.1 0.1 0.1 0.0 0.3 0.0 0.4 0.1 0.6 0.4 0.1 0.3 0.2 0.2 0.2 0.5 0.1 0.2 0.1 0.0 0.6 0.6 0.9 0.9 0.5 0.7 0.5 0.4 0.5 0.2 0.7 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 14.3 0.0 0.3 0.6 0.7 0.0 0.0 0.0 7.4 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 5.2 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 AC126283.1 ENSG00000285330 "Novel protein" 4 109713916-109801999 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast glandular cells: 1.4;Breast myoepithelial cells: 1.5;Collecting duct cells: 3.7;Endometrial ciliated cells: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 38.1;HDLM-2: 7.8;Hep G2: 8.4;RPTEC TERT1: 11.2" "HPA001143, HPA024061, HPA035909" Uncertain NA NA "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "HPA001143: AB_1078555, HPA024061: AB_1847129, HPA035909: AB_10672074" 1.5 3.5 0.3 3.4 0.3 0.1 1.5 0.3 0.8 1.9 0.5 1.6 6.2 2.1 0.0 3.4 2.1 3.1 4.1 0.3 0.4 3.6 9.7 2.3 1.8 0.8 0.2 3.2 9.0 1.2 3.6 0.4 2.1 2.1 3.5 2.5 1.2 3.4 0.7 5.3 2.1 0.4 2.4 2.3 1.4 0.3 1.3 1.9 4.1 1.5 4.1 0.6 0.0 1.0 0.0 0.3 0.2 0.4 0.0 1.5 2.9 0.0 0.3 0.2 38.1 0.2 6.5 0.7 0.6 0.1 0.2 0.1 0.0 7.8 0.7 0.1 0.5 8.4 5.8 0.4 0.0 6.0 0.0 0.0 0.1 1.9 4.8 0.1 0.5 2.5 0.1 0.0 0.1 0.3 0.2 0.1 0.0 0.1 0.3 0.2 11.2 1.1 0.2 0.3 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.2 0.3 0.1 0.5 0.0 0.1 0.1 6.9 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.3 0.8 0.3 0.4 0.8 0.2 0.4 0.4 0.3 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.5 0.0 0.0 0.0 3.7 0.0 0.0 0.2 0.0 0.0 0.1 0.0 3.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 AC132217.2 ENSG00000284779 "Novel protein" 11 2129112-2158391 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "liver: 37.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.0" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 37.6 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.1 0.2 0.3 0.3 0.4 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC134669.1 ENSG00000265118 "Novel protein" 17 31305213-31318831 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 4.9;lymphoid tissue: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 220.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "ASC TERT1: 3.6;HMC-1: 3.4;MOLT-4: 7.1;RPMI-8226: 5.5" HPA045033 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA045033: AB_2679191" "unprognostic (5.33e-2)" "unprognostic (3.44e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (5.88e-2)" "unprognostic (2.94e-2)" "unprognostic (2.40e-2)" "unprognostic (4.63e-2)" "unprognostic (3.23e-1)" "unprognostic (5.45e-5)" "unprognostic (1.89e-3)" "unprognostic (1.81e-1)" "unprognostic (4.53e-2)" 1.2 0.2 0.7 3.6 1.8 2.0 0.4 1.3 1.8 0.2 0.8 0.5 0.8 0.2 0.0 0.5 0.5 1.1 0.2 0.8 1.7 0.0 0.3 1.3 2.3 3.1 1.9 0.1 0.2 0.2 0.1 1.2 2.5 0.1 0.7 0.2 0.3 0.4 0.5 0.4 0.7 0.8 2.1 1.9 1.5 0.6 1.8 8.4 0.1 0.2 3.1 0.6 0.1 4.9 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.3 0.6 0.4 0.9 0.0 0.0 0.7 0.0 0.3 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 2.4 1.3 3.4 0.8 0.0 0.0 1.5 0.4 0.0 1.4 0.0 3.1 1.3 0.0 7.1 0.6 0.0 0.0 0.0 2.0 0.4 5.5 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 1.2 1.6 0.6 0.1 0.8 0.8 3.1 0.0 2.4 0.2 1.1 0.7 8.5 94.4 8.5 31.0 41.4 28.2 35.0 35.2 32.3 54.9 22.5 35.3 31.9 220.3 19.0 43.9 18.7 48.6 96.4 0.7 1.8 1.3 1.8 0.8 1.7 3.1 1.9 2.5 2.1 1.8 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 AC135050.2 ENSG00000255439 "Novel protein, VKORC1 and PRSS53 readthrough" 16 31083439-31094956 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skin 1: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 5.2;NB-4: 6.8;RPMI-8226: 8.7;U-266/70: 5.7" HPA042720 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (2.74e-1)" "unprognostic (9.61e-2)" "unprognostic (6.94e-2)" "unprognostic (2.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.68e-3)" "unprognostic (2.45e-3)" "unprognostic (1.34e-1)" "unprognostic (3.57e-1)" "unprognostic (2.79e-2)" "unprognostic (4.48e-3)" "unprognostic (8.49e-2)" "unprognostic (2.84e-8)" "unprognostic (4.96e-6)" "unprognostic (1.39e-1)" "unprognostic (4.81e-1)" "unprognostic (2.29e-4)" 0.4 0.1 0.0 0.3 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.7 0.1 0.3 0.1 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.7 0.2 0.2 0.1 0.1 0.1 0.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 1.1 0.4 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.3 0.1 0.9 0.4 0.0 0.4 1.0 1.2 0.3 5.2 0.3 0.0 0.2 0.2 0.3 3.4 1.8 0.1 0.0 0.2 0.0 0.1 0.0 1.3 2.7 0.8 0.3 0.2 0.0 0.5 1.1 0.3 0.2 0.2 0.0 0.2 0.0 0.6 0.0 0.7 0.1 0.4 0.8 6.8 0.1 0.0 1.5 3.4 0.3 8.7 0.0 0.3 2.1 2.6 1.2 0.4 1.0 0.0 0.0 0.2 1.3 0.5 0.0 1.6 0.5 5.7 0.7 0.6 1.2 0.9 0.2 0.6 0.7 2.5 2.0 0.8 2.7 2.1 2.1 2.8 0.9 1.6 1.3 1.9 0.9 0.9 1.8 1.6 2.8 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 AC135068.1 ENSG00000278263 "Novel protein, identical to IGHV4-4" 15 21742364-21742799 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 52.2;lymphoid tissue: 57.9;urinary bladder: 97.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 30 "memory B-cell: 24.0;naive B-cell: 7.7" "Lineage enriched" "Detected in single" 45 "B-cells: 24.0" "Not detected" "Not detected" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.48e-2)" "unprognostic (2.01e-1)" "unprognostic (1.93e-1)" "prognostic favorable (2.52e-4)" "unprognostic (1.05e-1)" "unprognostic (9.75e-3)" "unprognostic (1.80e-2)" "unprognostic (5.51e-6)" "unprognostic (5.57e-2)" "unprognostic (3.76e-1)" "unprognostic (1.49e-1)" "unprognostic (3.22e-1)" 1.0 0.0 0.2 27.3 0.1 4.2 5.4 0.0 0.0 3.7 0.0 52.2 22.6 0.2 0.0 3.7 0.5 0.5 2.1 0.1 0.0 0.2 1.0 5.5 5.5 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.4 22.1 0.0 30.1 2.1 0.0 1.1 6.0 0.0 0.0 9.4 22.3 0.1 0.0 7.8 0.7 0.0 57.9 97.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.2 0.0 0.0 7.7 0.3 0.0 0.0 0.0 0.0 0.0 0.5 1.9 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC135068.5 ENSG00000281179 "Novel gene identicle to IGHV1OR15-1" 15 21717808-21718245 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 78.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 0.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 94.3;naive B-cell: 111.6" "Group enriched" "Detected in many" 18 "B-cells: 111.6;T-cells: 60.9" "Group enriched" "Detected in some" 4 "JURKAT: 10.3;Karpas-707: 6.9;MOLT-4: 2.5" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "unprognostic (3.64e-1)" "unprognostic (8.63e-2)" 0.6 0.4 0.0 18.2 0.1 7.0 5.8 0.1 0.1 0.8 0.0 15.6 13.8 0.8 0.0 4.0 0.6 14.4 0.6 0.0 0.1 0.4 0.7 2.8 52.0 0.2 0.1 1.0 0.4 0.1 0.1 0.1 0.1 2.3 10.2 0.0 4.9 0.4 0.0 0.1 13.7 0.4 0.2 17.6 11.1 0.1 0.1 58.7 1.0 0.0 78.8 9.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 6.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 9.2 0.0 3.3 94.3 54.9 18.1 0.1 111.6 60.9 14.5 0.5 4.8 0.1 3.3 35.9 20.5 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC136352.3 ENSG00000277666 Unmapped 100123-101141 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA003342 Uncertain NA NA "HPA003342: AB_1078588" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC145212.1 ENSG00000277400 Q8WZ33 Unmapped 53590-115018 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 5.5;Basal respiratory cells: 8.0;Club cells: 4.6;Ionocytes: 8.2;Langerhans cells: 8.0;Melanocytes: 3.6;Respiratory ciliated cells: 5.4;Suprabasal keratinocytes: 6.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 14.1" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: CACO-2 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" 3.8 3.1 7.2 2.1 8.0 0.8 1.6 7.1 8.5 3.3 5.9 1.6 1.7 2.6 1.4 5.0 4.3 3.0 3.2 7.3 7.4 1.7 0.9 3.5 4.2 10.1 8.7 6.5 2.8 3.0 2.3 9.5 3.4 1.1 2.7 4.4 2.0 3.2 4.3 2.8 2.4 7.1 4.6 1.2 3.8 8.4 0.6 3.1 2.0 2.1 2.7 9.3 0.0 2.8 0.0 0.9 0.0 0.0 2.7 3.0 3.7 1.5 1.1 10.4 7.1 0.5 3.5 3.5 0.9 1.5 4.0 2.6 0.4 0.0 3.8 3.7 6.1 14.1 0.2 0.0 8.3 0.9 10.6 2.2 0.0 4.0 3.1 0.0 9.6 2.0 3.9 7.3 9.5 1.7 0.2 3.7 0.6 0.0 4.8 3.5 4.4 0.6 3.2 6.9 0.0 3.0 1.6 0.7 5.2 0.6 5.9 3.4 3.6 1.1 3.9 5.2 1.1 0.0 9.3 0.5 2.6 0.0 0.4 0.2 0.4 0.3 0.1 0.4 0.2 0.3 0.8 0.4 0.5 0.2 0.1 0.7 0.3 1.3 0.8 0.3 7.2 8.0 7.1 8.5 7.3 7.4 10.1 8.7 9.5 7.1 8.4 9.3 0.4 0.0 0.5 0.0 0.0 5.5 0.0 8.0 0.0 0.0 0.3 0.1 0.0 0.0 4.6 0.0 0.0 0.3 0.0 0.0 0.0 2.9 0.0 0.6 0.7 0.5 0.0 0.0 0.0 1.6 0.2 1.2 0.0 1.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 8.2 0.0 8.0 0.0 0.0 0.4 3.6 0.0 2.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.6 5.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 6.1 0.4 0.5 0.0 0.0 0.0 AC213203.1 ENSG00000268674 P0DMU3 Unmapped 35407-35916 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enriched" "Detected in single" 5 "brain: 1.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043267, HPA043292, HPA077864" Uncertain Approved "Intermediate filaments" NA NA "Cluster 21: B-cells - Adaptive immune response" "Intermediate filaments" "HPA043267: , HPA043292: , HPA077864: AB_2686862" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.8 0.3 0.1 0.2 0.3 0.2 0.1 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC233755.1 ENSG00000275063 "Immunoglobulin heavy variable 4-38-2-like" P0DP08 Unmapped 41444-41876 "Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 624.1;lymphoid tissue: 768.6;urinary bladder: 434.2" "Cell type enriched" "Detected in some" 196 "Plasma cells: 4861.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Group enriched" "Detected in some" 368 "memory B-cell: 403.0;naive B-cell: 259.1" "Lineage enriched" "Detected in single" 447 "B-cells: 403.0" "Cell line enriched" "Detected in some" 7 "REH: 141.7" "Secreted to blood" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: REH - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" 33.8 2.1 0.3 332.3 0.0 86.5 76.2 0.0 1.1 193.2 0.7 624.1 464.1 5.9 0.0 101.8 3.7 40.5 1.7 0.0 0.1 2.4 21.2 37.2 126.7 0.2 0.0 11.9 1.4 0.0 1.0 0.0 4.4 222.0 0.0 188.6 21.5 0.2 0.7 136.0 30.3 0.1 211.6 242.0 7.8 0.0 34.3 3.3 0.0 768.6 434.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.1 1.0 0.0 0.0 0.0 19.1 0.4 0.4 0.0 0.0 141.7 1.6 3.2 0.0 0.0 0.2 9.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.3 0.0 3.6 0.0 0.7 0.0 0.3 0.2 0.1 0.1 0.0 0.5 403.0 0.2 0.2 0.2 259.1 0.2 0.1 0.6 0.1 0.1 0.9 0.2 34.3 0.3 0.0 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4861.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 AC243967.1 ENSG00000267881 "Novel protein, readthrough between CEACAM5-CEACAM6" 19 41708657-41756737 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "intestine: 3.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "stomach cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "OE19: 1.3" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "unprognostic (1.55e-2)" "unprognostic (1.15e-2)" "unprognostic (9.59e-3)" 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 0.4 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC253536.7 ENSG00000285762 "Novel protein, AP000351.4-DDT readtrhough" 22 23971378-23980469 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 15.4;Club cells: 4.3;granulocytes: 3.8;Respiratory ciliated cells: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.1;HaCaT: 1.0;hTERT-RPE1: 2.2;RH-30: 1.2" "HPA049871, HPA074115" Uncertain Approved Mitochondria NA NA "Cluster 23: AN3-CA - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA049871: AB_2680926, HPA074115: " 0.1 0.3 0.1 0.3 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.3 0.3 0.1 0.0 0.3 0.2 0.0 0.4 0.4 0.1 0.5 0.0 0.4 0.3 0.0 0.0 0.2 0.8 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.5 0.2 0.0 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.9 1.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.1 0.4 0.4 0.3 0.0 0.3 0.5 0.0 6.4 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 ACACB "ACC2, ACCB, HACC275" ENSG00000076555 "Acetyl-CoA carboxylase beta" O00763 12 109116595-109268226 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 183.3;skeletal muscle: 173.2" "Cell type enhanced" "Detected in many" "Adipocytes: 128.7;Astrocytes: 136.8;Hepatocytes: 216.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 17.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 17.5" "Cell line enriched" "Detected in many" 18 "ASC diff: 222.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA006554 Enhanced "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "HPA006554: AB_1844495" "unprognostic (2.24e-1)" "unprognostic (4.66e-1)" "unprognostic (3.97e-2)" "unprognostic (4.54e-6)" "unprognostic (2.82e-1)" "unprognostic (1.59e-2)" "unprognostic (8.62e-3)" "unprognostic (5.81e-2)" "unprognostic (2.86e-1)" "unprognostic (1.63e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.63e-2)" "prognostic favorable (1.15e-5)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (1.21e-3)" "unprognostic (2.58e-2)" 183.3 19.8 19.6 3.3 21.7 3.6 100.5 7.6 11.4 12.9 26.9 37.2 8.4 12.0 3.5 10.6 12.1 10.9 35.4 10.1 11.2 12.6 54.3 6.7 3.8 12.7 19.4 14.3 19.2 17.9 11.2 2.5 11.6 11.8 8.2 1.7 12.5 11.7 173.2 9.5 15.5 9.4 6.7 7.8 18.6 4.9 19.1 4.5 18.1 61.5 3.0 23.0 11.5 13.2 0.9 5.7 3.6 6.9 222.6 1.7 2.6 0.9 1.5 1.0 0.6 4.1 1.1 2.9 1.6 1.2 2.4 4.8 3.0 1.5 0.6 3.8 5.3 6.6 6.2 4.3 1.0 5.7 1.6 2.6 1.5 2.3 0.6 1.7 0.5 4.9 0.7 0.3 0.7 1.7 4.1 5.3 3.9 0.4 12.4 2.2 4.8 1.5 1.8 2.0 2.3 5.4 5.9 2.8 3.4 1.5 2.6 5.9 0.4 2.2 1.3 2.5 1.9 8.8 5.3 4.0 5.3 4.5 1.7 4.6 0.4 17.5 1.1 0.1 0.6 2.2 1.0 0.3 0.2 3.0 1.8 0.9 0.7 0.1 0.2 0.3 0.6 0.1 19.6 21.7 7.6 11.4 10.1 11.2 12.7 19.4 11.6 6.7 19.1 13.2 128.7 6.4 1.1 136.8 3.7 2.3 2.6 1.0 3.4 3.1 32.5 5.0 35.3 25.8 1.7 23.9 0.0 0.6 2.4 13.9 1.9 2.1 34.3 3.3 3.4 26.0 10.2 25.7 5.1 4.0 0.5 16.0 18.3 1.3 1.3 20.0 41.4 216.5 1.7 23.5 6.4 9.6 0.0 12.6 2.4 36.4 29.2 3.7 5.4 28.1 1.2 5.2 2.1 29.7 25.8 2.7 7.3 50.4 2.5 0.9 17.9 6.5 2.3 4.1 6.6 29.3 12.0 2.3 3.0 2.5 1.6 0.1 3.5 21.8 11.8 1.1 ACAN "AGC1, CSPG1, CSPGCP, MSK16" ENSG00000157766 Aggrecan P16112 15 88803436-88875353 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.5;seminal vesicle: 3.1" "Group enriched" "Detected in some" 15 "Extravillous trophoblasts: 127.1;Granulosa cells: 132.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "WM-115: 24.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016377, HPA038241, HPA038242" Enhanced "Secreted to extracellular matrix" NA NA 17000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "CAB016377: AB_626650, HPA038241: AB_2675909, HPA038242: AB_2675910" "unprognostic (2.69e-3)" "unprognostic (4.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.43e-2)" "unprognostic (2.13e-2)" "unprognostic (1.40e-2)" "unprognostic (1.15e-1)" "unprognostic (7.12e-2)" "unprognostic (8.57e-2)" "unprognostic (2.34e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (7.79e-2)" "unprognostic (1.53e-1)" "unprognostic (7.71e-2)" "unprognostic (7.27e-2)" 1.2 0.2 0.6 0.9 1.0 0.1 0.1 2.2 1.6 0.9 0.1 0.3 0.1 0.4 0.2 0.1 0.2 0.7 0.5 0.7 6.5 0.7 0.1 0.7 0.1 2.1 1.6 0.4 0.2 0.1 0.4 0.2 1.5 0.5 0.3 0.1 0.1 3.1 0.2 0.2 0.1 0.5 1.3 0.2 0.2 1.4 1.5 0.0 0.3 0.0 0.0 0.8 0.7 1.4 0.0 0.0 0.0 0.0 0.8 0.0 4.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 2.2 1.6 0.7 6.5 2.1 1.6 1.5 1.3 1.5 1.4 0.1 0.0 0.0 0.7 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.0 1.2 0.0 127.1 0.7 0.0 0.4 1.3 132.4 0.0 0.0 2.5 0.0 4.5 0.0 0.0 0.0 0.5 2.1 0.0 0.2 1.8 1.0 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 8.4 2.3 6.3 0.0 0.4 3.6 0.1 1.8 0.0 0.4 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 265.1;testis: 101.9" "Group enriched" "Detected in many" 20 "Early spermatids: 543.6;Late spermatids: 1322.9;Proximal enterocytes: 1172.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC TERT1: 63.3;HUVEC TERT2: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 13.4 4.9 1.7 4.8 8.1 0.1 8.1 0.2 2.5 18.1 0.5 11.2 176.4 8.1 3.5 4.1 6.3 8.2 10.4 1.3 1.0 10.8 1.9 49.0 4.9 1.3 0.9 1.9 6.2 18.7 9.2 11.6 1.3 8.9 6.1 0.4 7.6 23.8 16.1 3.8 265.1 9.6 0.8 2.8 8.3 101.9 2.0 0.8 19.2 10.0 2.1 5.5 3.8 1.1 0.0 0.0 0.0 0.0 2.6 63.3 0.6 2.4 4.7 0.0 0.0 0.9 5.1 1.3 1.8 11.4 0.1 0.0 3.1 0.0 0.0 0.0 1.4 6.6 0.0 0.0 1.4 0.0 0.0 4.2 0.0 0.1 0.0 1.2 33.8 0.0 5.8 0.0 0.1 1.1 0.0 1.4 0.4 11.7 0.7 0.1 0.5 0.9 0.0 0.0 8.2 5.6 0.0 0.0 0.0 1.3 2.9 0.4 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 8.1 0.2 2.5 1.3 1.0 1.3 0.9 1.3 0.8 2.0 1.1 50.0 0.0 3.3 0.0 0.5 1.5 2.6 0.1 1.2 4.0 3.6 1.9 2.1 1.5 0.7 0.0 0.0 0.1 0.3 11.9 0.0 5.9 543.6 10.8 8.0 34.7 18.0 0.0 4.7 0.4 0.1 11.5 2.0 36.3 7.0 24.1 3.6 0.8 4.2 0.0 1.8 39.8 0.0 33.7 3.5 1322.9 4.4 13.6 3.6 4.7 0.0 1.8 0.0 1.0 0.2 0.7 40.9 2.6 0.1 4.2 1172.8 21.7 0.0 1.1 0.0 2.0 4.2 13.5 6.4 0.2 0.1 0.1 2.2 0.3 26.2 2.1 ACHE YT ENSG00000087085 "Acetylcholinesterase (Cartwright blood group)" P22303 7 100889994-100896974 "Blood group antigen proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter degradation" "Blood group antigen, Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 98.2;skeletal muscle: 163.2;tongue: 48.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 86.2;Erythroid cells: 37.7;Exocrine glandular cells: 39.7;Horizontal cells: 55.5;Paneth cells: 118.3;Proximal enterocytes: 45.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.9;CACO-2: 13.0;K-562: 13.9;Karpas-707: 19.7;U-2 OS: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027098 Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 990000 "Cluster 80: Striated muscle - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "HPA027098: AB_2672111" "unprognostic (2.23e-1)" "unprognostic (9.44e-2)" "unprognostic (2.71e-2)" "unprognostic (5.80e-3)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.49e-1)" "unprognostic (2.54e-1)" "unprognostic (1.36e-2)" "unprognostic (2.48e-2)" "unprognostic (8.92e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.88e-5)" "unprognostic (2.95e-1)" "unprognostic (2.59e-2)" "unprognostic (9.28e-2)" "unprognostic (8.38e-2)" 1.4 4.7 20.9 2.2 16.8 7.9 2.0 37.1 32.5 5.0 0.0 7.6 4.9 2.6 0.2 2.3 3.2 1.3 12.5 8.0 98.2 8.8 4.1 4.4 3.5 66.1 54.2 4.6 4.3 4.7 8.3 0.7 72.7 8.1 1.8 5.7 7.1 1.6 163.2 1.3 9.1 0.5 26.2 3.5 2.4 3.9 58.1 3.6 2.3 48.0 1.5 1.4 3.7 10.5 0.0 0.2 0.2 0.2 0.3 0.0 7.9 0.3 0.0 0.1 0.2 13.0 0.1 0.0 0.6 0.0 1.2 0.6 2.0 0.1 0.0 4.6 0.5 0.2 0.1 0.2 0.1 0.0 0.4 0.5 0.1 0.1 0.0 0.0 0.0 0.1 13.9 19.7 0.1 4.3 0.0 0.2 1.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.8 1.5 0.1 0.8 0.0 2.9 0.0 0.0 0.2 0.5 6.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.9 16.8 37.1 32.5 8.0 98.2 66.1 54.2 72.7 26.2 58.1 10.5 0.5 0.0 0.0 3.3 0.5 0.8 20.9 0.9 6.2 13.5 2.9 1.1 6.4 5.7 0.4 0.0 0.0 8.2 0.9 86.2 0.0 10.5 0.0 0.5 1.5 2.1 3.5 37.7 4.7 39.7 2.6 3.0 1.5 2.4 0.0 7.4 2.2 0.4 0.8 55.5 9.7 12.0 0.0 0.3 6.6 0.4 0.6 1.7 1.8 1.0 4.6 11.4 0.0 8.5 0.8 20.1 118.3 0.7 1.8 20.4 45.6 1.1 0.1 6.8 0.0 13.5 4.9 4.1 8.0 1.7 1.0 7.1 0.6 1.4 4.6 15.2 ACP1 "HAAP, LMW-PTP, LMWPTP" ENSG00000143727 "Acid phosphatase 1" P24666 2 264140-278283 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 1061.1;Late spermatids: 2128.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA016754 Approved Approved Nucleoplasm,Cytosol NA NA 2000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "HPA016754: AB_1844505" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (6.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (6.67e-6)" "unprognostic (2.45e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (9.72e-3)" "unprognostic (4.89e-2)" "unprognostic (2.71e-2)" "unprognostic (7.10e-2)" "unprognostic (2.88e-2)" "unprognostic (3.39e-2)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" 41.2 104.0 43.1 45.5 47.6 91.9 64.7 43.9 54.0 43.4 63.9 61.4 64.0 46.6 69.3 43.3 57.9 45.4 57.3 49.4 47.1 78.1 106.4 46.8 66.2 43.4 44.2 59.2 94.1 73.9 59.2 61.7 44.3 52.1 64.7 72.7 71.1 44.2 76.6 41.3 60.7 41.5 44.9 44.7 67.1 46.1 45.3 66.2 63.7 74.9 61.9 47.5 36.4 50.2 78.3 112.5 177.4 97.4 76.1 77.1 142.2 92.6 97.7 91.9 80.8 151.7 78.5 48.8 70.7 85.1 114.6 76.5 169.4 97.0 82.3 118.7 157.9 142.3 99.0 348.5 105.7 162.5 80.4 78.7 90.5 81.9 102.3 95.5 105.8 176.9 145.1 95.1 110.9 103.1 178.5 161.3 214.1 204.7 111.7 118.2 176.1 114.5 144.2 110.5 191.6 191.3 56.0 137.6 196.3 115.0 82.1 89.8 88.9 101.3 65.2 84.0 142.6 123.8 261.2 150.4 120.0 138.9 123.7 65.4 61.6 57.2 88.8 75.2 118.1 106.6 100.4 103.2 57.3 97.2 118.1 115.2 10.9 121.5 80.2 65.3 117.6 115.0 43.1 47.6 43.9 54.0 49.4 47.1 43.4 44.2 44.3 44.9 45.3 50.2 62.5 44.8 96.7 9.1 102.6 79.2 105.3 173.4 51.8 53.1 118.8 130.0 84.9 131.5 119.6 68.0 8.4 207.1 101.3 81.9 270.1 226.7 1061.1 113.1 56.2 70.6 82.5 291.5 20.4 169.0 279.7 74.2 54.6 85.5 70.3 95.9 56.0 115.8 141.1 28.6 21.0 125.1 126.1 72.0 66.3 2128.2 94.4 74.6 81.8 16.9 117.8 92.2 152.4 19.6 26.0 174.4 109.2 92.2 106.4 187.0 174.2 306.6 128.1 56.9 92.1 42.5 87.0 122.6 137.4 87.4 91.2 187.7 86.0 124.4 143.9 148.3 ACP2 LAP ENSG00000134575 "Acid phosphatase 2, lysosomal" P11117 11 47239302-47248906 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 89.3;Hofbauer cells: 113.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 69.9" "Lineage enriched" "Detected in all" 5 "monocytes: 69.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 12000 "Cluster 51: Monocytes - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (5.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.86e-2)" "prognostic favorable (1.04e-4)" "unprognostic (7.90e-3)" "unprognostic (2.93e-1)" "unprognostic (6.16e-3)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (3.28e-3)" "unprognostic (2.64e-3)" "unprognostic (5.42e-2)" "unprognostic (1.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.20e-1)" "unprognostic (8.68e-3)" "unprognostic (1.57e-1)" 25.2 36.6 17.3 22.9 17.1 6.4 21.8 17.0 18.5 16.5 22.1 23.3 42.9 15.8 29.8 14.3 14.1 19.6 21.7 19.8 26.0 27.4 80.5 21.4 29.4 20.8 19.6 11.1 45.9 21.3 21.3 28.7 23.1 25.4 18.1 11.9 50.3 18.3 14.0 11.4 31.9 16.9 16.9 29.1 24.8 12.2 22.0 13.7 19.3 14.8 15.3 22.0 13.1 17.2 16.5 33.5 31.9 28.2 28.1 13.6 24.4 26.6 47.1 47.5 49.4 23.3 26.3 4.3 21.9 34.2 14.3 23.7 16.9 24.6 22.5 85.5 29.1 11.1 48.1 24.6 38.4 16.4 27.1 34.1 15.2 24.6 14.5 28.3 34.9 14.1 20.3 33.9 31.5 26.8 13.4 14.2 21.5 24.8 20.0 10.8 43.1 36.2 34.9 37.6 16.7 26.0 36.8 80.1 19.2 16.3 49.0 14.0 21.0 23.9 19.8 31.4 38.4 28.1 40.0 3.6 35.0 8.2 37.6 12.5 16.9 7.2 12.3 69.9 9.4 2.5 7.6 11.1 15.1 1.5 6.6 5.7 2.8 9.7 48.2 0.6 8.3 10.9 17.3 17.1 17.0 18.5 19.8 26.0 20.8 19.6 23.1 16.9 22.0 17.2 13.3 19.2 18.6 6.2 5.6 4.1 9.3 42.2 10.2 14.4 13.5 9.1 9.2 21.5 29.4 18.4 6.2 41.3 2.6 37.6 9.8 50.6 1.8 7.7 15.6 18.3 15.0 13.5 6.9 60.1 33.3 15.3 17.3 12.1 12.0 10.7 45.7 89.3 113.5 11.8 8.9 26.7 22.4 80.0 3.9 3.5 5.0 33.8 24.9 3.7 29.8 20.6 7.2 8.5 4.3 33.5 29.5 10.5 21.1 10.9 55.3 33.4 19.2 11.9 19.7 8.1 14.5 11.8 19.1 9.5 2.4 29.3 5.8 25.2 14.3 8.6 ACP3 "ACP-3, ACPP, PAP, TM-PAP" ENSG00000014257 "Acid phosphatase 3" P15309 3 132317369-132368298 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 76 "prostate: 3643.7" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 13.9;Hofbauer cells: 4.7;Syncytiotrophoblasts: 8.9" "Cancer enriched" "Detected in many" 275 "prostate cancer: 1227.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 139.7" "Lineage enhanced" "Detected in many" "granulocytes: 139.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 17.7;OE19: 22.3;RPMI-8226: 58.0;U-698: 17.2;U-87 MG: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000071, HPA004335, HPA063916" Enhanced "Secreted to blood" NA NA 460000 480000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "CAB000071: , HPA004335: AB_1079684, HPA063916: AB_2685152" "unprognostic (6.67e-2)" "unprognostic (4.70e-2)" "unprognostic (1.76e-1)" "unprognostic (7.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.58e-2)" "unprognostic (2.46e-1)" "unprognostic (7.41e-2)" "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (2.14e-1)" "unprognostic (5.95e-2)" "unprognostic (9.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-1)" "unprognostic (3.91e-2)" "unprognostic (1.71e-1)" 3.1 5.4 0.9 7.3 1.3 17.5 3.4 0.9 0.9 6.3 1.2 3.6 3.1 1.4 17.2 47.7 2.2 1.5 0.6 1.2 1.5 28.9 1.4 4.5 1.9 1.5 1.3 1.1 2.7 3.9 0.5 10.8 1.5 3643.7 6.5 0.4 10.6 0.8 0.2 27.0 3.4 1.8 1.0 1.8 3.2 2.4 1.0 1.0 2.4 0.2 6.5 1.8 12.1 1.7 0.5 0.1 0.0 0.0 0.2 0.9 11.7 0.3 17.7 0.1 0.0 0.4 0.4 10.6 0.8 0.0 0.1 4.8 0.0 0.1 0.0 0.1 0.5 2.0 0.4 0.2 0.2 7.3 0.1 1.1 1.6 0.1 0.0 0.2 0.0 0.0 0.1 2.7 0.2 0.1 0.0 13.5 0.7 22.3 2.1 0.1 0.0 58.0 5.0 6.5 0.0 4.1 0.1 2.0 0.6 1.7 0.3 6.5 0.0 0.1 0.1 2.5 0.1 0.8 0.4 17.2 14.9 12.7 0.2 0.1 30.2 139.7 0.2 26.9 0.2 0.7 0.0 0.0 35.3 0.0 0.0 0.0 26.4 2.6 25.8 2.4 0.0 10.1 0.9 1.3 0.9 0.9 1.2 1.5 1.5 1.3 1.5 1.0 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 ACP5 "HPAP, TRAP" ENSG00000102575 "Acid phosphatase 5, tartrate resistant" P13686 19 11574660-11579008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 174.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 426.9;Hofbauer cells: 426.7;Macrophages: 298.2;Proximal tubular cells: 145.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 200.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 41.1;K-562: 30.4;RPMI-8226: 41.4;SK-MEL-30: 127.6;U-138 MG: 102.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002584, HPA057655, HPA059463" Enhanced Uncertain Cytosol "Intracellular and membrane" NA NA 4000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB002584: AB_564039, HPA057655: AB_2683490, HPA059463: AB_2684028" "unprognostic (4.27e-2)" "unprognostic (2.05e-2)" "unprognostic (2.93e-1)" "unprognostic (8.60e-3)" "unprognostic (2.96e-1)" "unprognostic (1.95e-2)" "unprognostic (5.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.13e-2)" "unprognostic (3.80e-1)" "unprognostic (3.66e-3)" "unprognostic (9.09e-2)" "unprognostic (1.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" 9.4 6.0 2.2 42.4 3.9 9.4 25.6 2.5 21.4 34.7 3.0 46.4 31.9 19.2 7.8 23.4 8.6 26.7 5.1 1.9 3.9 74.0 32.5 174.1 87.1 4.1 3.1 20.3 11.9 2.4 1.3 13.3 6.0 19.6 36.4 20.1 14.3 7.0 1.4 24.9 30.2 13.3 4.1 43.5 38.7 4.0 15.7 25.4 3.0 5.0 43.6 33.1 11.3 5.7 10.2 1.1 0.0 0.2 0.5 0.0 41.1 1.1 25.8 0.0 0.1 0.4 0.3 1.4 1.8 9.0 5.9 0.3 0.0 4.5 0.1 12.1 0.8 0.3 0.0 5.0 1.4 0.1 0.6 0.0 4.1 0.4 0.0 0.0 0.0 0.0 30.4 0.2 0.0 2.3 0.9 1.4 0.8 0.3 0.7 0.4 1.8 41.4 0.0 0.4 0.7 1.0 0.0 0.0 127.6 1.1 0.2 0.4 0.9 102.9 1.2 1.8 0.3 0.7 5.7 0.6 23.7 0.1 4.0 0.4 35.3 76.6 15.8 36.1 8.8 200.1 26.0 19.6 7.3 110.9 35.3 20.2 10.4 13.3 36.3 62.5 67.8 36.4 2.2 3.9 2.5 21.4 1.9 3.9 4.1 3.1 6.0 4.1 15.7 5.7 2.2 9.6 7.8 0.0 75.7 10.3 11.0 21.8 25.0 18.3 14.6 18.4 1.4 15.7 5.7 7.3 18.8 33.4 21.2 7.0 9.8 1.8 0.2 0.7 9.1 30.9 3.0 24.5 0.0 11.3 32.7 19.8 10.7 0.9 63.7 0.8 426.9 8.4 426.7 1.7 0.0 4.7 10.2 106.0 68.6 0.7 1.8 298.2 14.2 1.0 79.8 48.5 8.2 0.0 0.1 4.4 20.4 12.0 33.4 14.5 12.7 145.8 2.5 41.4 0.0 0.4 2.8 0.1 0.2 14.6 11.1 26.1 29.5 0.1 6.7 6.1 ACP6 "ACPL1, LPAP" ENSG00000162836 "Acid phosphatase 6, lysophosphatidic" Q9NPH0 1 147629652-147670524 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 108.9;RPTEC TERT1: 119.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028560 Uncertain "Intracellular and membrane" NA NA 64000 "Cluster 35: T-regs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA028560: AB_10602427" "unprognostic (3.17e-2)" "unprognostic (3.01e-2)" "unprognostic (3.50e-1)" "unprognostic (1.87e-2)" "unprognostic (3.85e-1)" "unprognostic (8.50e-3)" "unprognostic (3.36e-3)" "unprognostic (1.00e-1)" "unprognostic (6.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.09e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (3.94e-1)" "unprognostic (8.07e-2)" "unprognostic (1.26e-1)" "prognostic favorable (6.44e-4)" 6.3 13.6 6.2 4.2 6.3 5.0 17.8 5.6 6.6 11.8 7.9 11.4 7.4 8.3 16.2 7.8 12.7 6.8 8.4 5.9 6.3 17.5 13.2 7.3 3.9 6.3 6.9 9.3 11.0 21.9 15.2 4.2 6.2 12.6 9.7 3.6 10.4 11.2 6.7 9.3 8.8 6.0 6.0 6.0 12.4 5.7 6.1 7.9 15.2 6.0 6.9 11.2 6.7 5.7 21.1 8.5 7.1 12.7 4.5 4.3 20.2 4.8 14.8 14.8 17.5 10.2 31.9 6.1 17.4 10.4 11.4 35.6 9.6 32.0 15.4 8.2 16.1 21.9 11.8 19.4 13.2 3.9 0.8 6.3 23.3 7.7 15.4 17.6 15.2 30.2 10.5 3.4 17.0 15.8 16.5 10.0 17.0 108.9 62.9 11.7 6.1 70.9 119.7 41.3 5.8 7.1 17.5 12.5 36.5 15.9 20.3 6.0 10.7 4.6 8.6 0.9 15.1 13.4 21.3 2.8 8.7 0.3 25.8 0.1 2.3 13.4 4.6 0.8 7.9 2.6 7.5 6.1 5.4 2.8 8.2 7.0 3.5 0.3 0.3 3.4 14.8 2.7 6.2 6.3 5.6 6.6 5.9 6.3 6.3 6.9 6.2 6.0 6.1 5.7 2.1 19.2 13.9 74.4 2.9 1.1 6.1 7.4 7.4 3.1 6.3 6.3 7.0 10.0 6.7 16.5 0.0 19.7 7.0 3.7 17.6 7.5 6.0 9.1 2.3 2.4 9.1 4.2 14.2 15.3 7.2 2.4 10.7 9.4 1.3 15.2 5.3 10.9 4.6 0.0 20.6 8.5 8.2 4.8 6.7 1.5 5.9 2.9 3.6 15.0 3.4 8.8 4.1 18.1 10.4 18.7 5.4 4.1 3.8 4.9 6.3 14.4 11.9 1.1 13.1 5.7 7.7 7.5 4.7 9.1 1.3 8.1 9.6 7.3 8.5 5.8 ACP7 "FLJ16165, PAPL, PAPL1" ENSG00000183760 "Acid phosphatase 7, tartrate resistant (putative)" Q6ZNF0 19 39083913-39111493 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 6.6;lymphoid tissue: 2.6;skin 1: 6.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 0.8;head and neck cancer: 2.6;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 33.3;U-87 MG: 45.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA042613 Uncertain "Secreted - unknown location" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "HPA042613: AB_10963214" "unprognostic (6.35e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-3)" "unprognostic (1.92e-3)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (4.94e-3)" "unprognostic (2.66e-1)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" "unprognostic (1.51e-5)" "unprognostic (4.36e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-2)" "unprognostic (2.42e-1)" 0.0 0.0 1.7 0.0 3.3 0.0 0.2 6.6 2.7 0.7 0.8 0.0 0.0 0.0 0.4 0.7 0.0 0.2 0.0 2.0 2.2 0.0 0.0 0.0 0.0 3.9 3.7 0.0 0.0 0.3 0.0 0.0 3.8 0.3 0.0 0.0 0.5 0.0 0.0 6.0 0.0 0.0 2.0 0.0 0.1 0.0 3.0 0.0 0.0 0.0 2.6 0.1 0.6 4.1 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.6 0.8 0.4 5.2 0.0 0.0 0.0 33.3 0.3 0.0 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 9.5 0.3 0.0 0.1 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.1 1.1 0.0 0.0 0.0 0.0 0.0 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.3 6.6 2.7 2.0 2.2 3.9 3.7 3.8 2.0 3.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 ACR ENSG00000100312 Acrosin P10323 22 50738196-50745339 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "testis: 86.7" "Group enriched" "Detected in some" 33 "Early spermatids: 492.2;Late spermatids: 134.8;Spermatocytes: 216.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA048687 Enhanced "Secreted in male reproductive system" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA048687: AB_2680494" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" "unprognostic (6.27e-3)" "unprognostic (3.58e-2)" "unprognostic (8.04e-2)" "unprognostic (3.30e-3)" "unprognostic (5.41e-2)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (1.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (1.25e-1)" 2.6 0.2 0.4 0.0 0.5 0.0 2.0 0.4 0.5 0.8 2.6 0.5 0.1 1.1 0.7 0.4 1.1 0.2 1.0 0.4 0.3 0.9 0.8 2.0 0.0 0.3 0.3 0.3 0.2 0.0 0.5 0.1 0.5 0.6 0.0 0.1 0.6 0.2 0.8 0.8 0.5 0.2 0.4 3.0 0.3 86.7 0.4 0.0 0.6 0.0 0.0 0.6 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.5 0.4 0.3 0.3 0.3 0.5 0.4 0.4 0.4 8.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 2.2 0.0 0.3 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 492.2 0.4 0.1 4.7 3.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 7.5 0.1 0.1 0.0 0.2 0.8 0.0 0.0 0.0 134.8 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.8 2.6 0.0 0.0 1.2 0.4 0.0 0.0 6.6 0.3 0.1 216.9 2.5 0.3 0.0 0.0 0.0 0.1 1.5 0.2 ACRBP "CT23, OY-TES-1, SP32" ENSG00000111644 "Acrosin binding protein" Q8NEB7 12 6638075-6647433 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "testis: 283.5" "Cell type enhanced" "Detected in many" "Early spermatids: 1097.8;Late spermatids: 723.5;Macrophages: 220.0;Spermatocytes: 387.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "classical monocyte: 12.5;intermediate monocyte: 15.8;myeloid DC: 17.7;non-classical monocyte: 31.0" "Group enriched" "Detected in many" 9 "dendritic cells: 17.7;monocytes: 31.0" "Cell line enhanced" "Detected in some" "HEL: 5.3;HMC-1: 6.7;U-266/70: 15.0;U-266/84: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039081, HPA039082" Enhanced Approved Nucleoplasm,Vesicles "Secreted in male reproductive system" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" "HPA039081: AB_10670920, HPA039082: AB_10671036" "unprognostic (7.76e-3)" "unprognostic (2.27e-1)" "unprognostic (3.41e-3)" "unprognostic (2.31e-2)" "unprognostic (3.65e-2)" "unprognostic (2.13e-2)" "unprognostic (2.42e-1)" "unprognostic (3.40e-3)" "unprognostic (2.85e-1)" "unprognostic (5.47e-3)" "unprognostic (1.17e-2)" "unprognostic (1.43e-1)" "unprognostic (9.41e-3)" "unprognostic (1.25e-1)" "unprognostic (2.56e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-4)" 2.2 0.9 0.9 3.8 1.3 10.7 1.1 1.9 1.4 1.9 1.1 2.9 8.4 1.4 14.2 0.9 2.1 4.1 0.6 0.9 1.0 1.8 2.2 2.8 5.5 1.3 1.2 0.7 2.9 0.3 0.9 2.3 1.3 2.0 2.1 1.8 1.3 1.1 0.4 1.7 8.1 2.1 1.1 9.2 1.9 283.5 1.2 3.0 13.8 0.4 3.6 2.4 0.9 1.5 0.2 0.1 0.8 2.5 0.8 1.2 1.3 0.0 0.0 0.1 0.1 0.0 1.8 0.3 0.8 0.2 0.1 0.0 0.4 0.0 0.2 0.8 0.0 5.3 0.6 0.0 1.8 0.1 6.7 0.1 3.3 0.9 0.1 0.6 0.6 1.7 3.5 0.0 0.1 0.3 0.2 1.9 1.5 4.3 0.0 0.3 0.1 0.3 0.5 0.1 1.0 0.3 0.0 0.7 1.1 1.2 0.0 1.9 0.7 0.1 0.8 0.5 0.0 15.0 10.5 0.5 0.5 2.0 0.0 1.5 12.5 1.2 0.2 15.8 0.0 1.3 0.0 0.0 17.7 1.9 0.2 0.1 2.6 0.7 31.0 4.5 0.0 10.6 0.9 1.3 1.9 1.4 0.9 1.0 1.3 1.2 1.3 1.1 1.2 1.5 0.3 0.0 1.3 0.7 1.5 0.1 0.1 0.0 1.2 1.7 0.5 0.5 1.0 0.0 0.1 0.0 0.0 0.1 1.9 0.9 0.0 0.2 1097.8 0.7 0.5 1.5 0.0 5.7 0.2 0.5 0.3 0.5 0.0 0.8 6.3 0.4 1.8 0.3 9.8 0.0 0.3 0.8 0.0 20.5 3.4 723.5 8.1 220.0 0.0 1.0 7.6 1.1 10.3 0.0 0.4 0.1 1.6 4.5 0.5 0.0 7.6 1.1 0.2 1.3 6.6 0.3 0.2 387.5 7.5 0.3 0.0 0.1 1.0 0.4 1.1 0.1 ACRV1 "D11S4365, SP-10, SPACA2" ENSG00000134940 "Acrosomal vesicle protein 1" P26436 11 125671522-125680874 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 116.7" "Group enriched" "Detected in some" 48 "Early spermatids: 904.8;Late spermatids: 278.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 5.0;HEL: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038718, HPA038719" Enhanced "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "HPA038718: AB_2676171, HPA038719: AB_10670787" "unprognostic (3.58e-2)" "unprognostic (8.68e-3)" "unprognostic (1.46e-1)" "unprognostic (6.18e-2)" "unprognostic (4.58e-2)" "unprognostic (7.91e-3)" "unprognostic (6.73e-4)" "unprognostic (1.76e-1)" "unprognostic (2.12e-3)" "unprognostic (8.39e-2)" "unprognostic (7.09e-2)" "unprognostic (2.90e-3)" "unprognostic (1.80e-8)" "unprognostic (5.26e-3)" "unprognostic (2.52e-1)" "unprognostic (1.95e-1)" "unprognostic (3.75e-1)" 0.0 0.0 1.8 0.1 1.9 0.2 0.1 1.3 2.0 0.0 1.2 0.1 0.1 0.1 3.5 0.0 0.1 0.0 0.0 1.7 1.6 0.0 0.0 0.0 0.4 1.5 1.5 0.0 0.0 0.0 0.2 0.1 1.6 0.2 0.0 0.2 0.0 0.7 0.0 0.1 0.1 0.2 1.6 0.0 0.0 116.7 1.9 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.3 1.2 5.0 3.2 0.0 0.0 1.0 1.5 0.0 0.1 0.0 1.8 1.7 2.7 0.6 0.0 0.7 0.4 0.0 0.0 0.3 1.9 0.9 5.0 0.6 0.9 0.1 2.5 1.1 0.0 0.0 0.0 0.2 0.2 0.0 0.8 1.4 2.0 0.4 0.7 2.7 3.4 1.1 0.5 1.0 2.3 1.2 0.5 0.0 0.5 0.6 0.8 0.6 0.1 0.1 0.9 0.9 0.6 0.5 1.7 1.1 0.2 0.3 0.9 1.2 1.3 0.2 1.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 1.9 1.3 2.0 1.7 1.6 1.5 1.5 1.6 1.6 1.9 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 904.8 0.8 0.1 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 278.8 6.2 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 ACSF2 "ACSMW, FLJ20920" ENSG00000167107 "Acyl-CoA synthetase family member 2" Q96CM8 17 50426158-50474845 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 142.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 85.8;Proximal enterocytes: 78.2;Proximal tubular cells: 128.4;Syncytiotrophoblasts: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 97.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024693 Enhanced Uncertain Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Microtubules, Cytosol" "HPA024693: AB_2671654" "unprognostic (1.40e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (1.53e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-1)" "unprognostic (8.48e-2)" "unprognostic (1.14e-2)" "unprognostic (6.49e-2)" "unprognostic (7.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (2.45e-2)" "prognostic favorable (2.41e-4)" 24.8 71.9 7.6 5.7 8.5 3.3 21.0 7.7 10.1 18.9 8.6 26.9 22.1 6.7 15.8 7.7 9.7 10.8 25.9 7.1 7.0 142.1 36.4 17.8 8.5 8.5 7.3 19.3 6.8 9.9 2.9 15.4 8.0 15.0 17.5 1.1 15.8 16.0 41.3 22.5 20.2 5.4 8.2 8.4 18.8 4.9 7.9 5.6 42.5 25.8 8.2 17.8 13.4 7.7 24.8 8.1 6.6 15.8 68.1 12.1 38.1 5.9 8.6 12.6 24.5 32.1 47.2 15.7 12.6 7.3 11.5 14.7 4.7 29.2 15.3 19.5 11.2 27.3 3.9 58.5 11.4 3.3 24.3 54.9 44.4 15.8 2.1 45.4 17.4 20.3 3.2 8.8 13.7 31.3 8.8 11.1 1.1 47.5 11.9 20.6 4.8 41.2 4.2 97.2 21.6 11.3 11.8 17.3 12.3 13.7 15.5 22.8 12.7 22.5 6.8 3.5 1.9 15.4 3.1 8.2 9.3 17.1 1.4 0.0 2.9 15.3 2.0 7.7 1.7 8.6 1.5 2.1 16.1 2.0 0.7 0.9 0.5 1.6 7.0 6.3 5.5 2.7 7.6 8.5 7.7 10.1 7.1 7.0 8.5 7.3 8.0 8.2 7.9 7.7 3.2 28.9 24.3 27.1 7.3 6.0 23.3 17.0 25.0 0.0 20.8 16.0 25.9 11.5 19.9 3.7 0.0 85.8 1.7 59.5 11.7 13.5 0.4 4.9 3.5 4.9 10.2 1.3 0.3 4.3 11.7 6.5 21.9 7.7 22.2 24.5 4.2 44.4 21.9 0.0 0.3 20.6 2.0 9.8 11.0 1.6 26.8 11.0 3.6 17.8 12.7 6.1 5.2 3.5 0.5 5.7 53.1 14.3 2.6 3.5 78.2 128.4 14.6 0.2 0.0 2.7 5.9 0.2 2.2 5.4 7.0 81.0 4.1 12.1 25.8 14.0 ACSF3 ENSG00000176715 "Acyl-CoA synthetase family member 3" Q4G176 16 89088375-89164121 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 242.9;U-698: 113.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008322 Supported Nucleoplasm,Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 9: Intestine - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria Nucleoplasm "HPA008322: AB_1845294" "unprognostic (1.94e-1)" "unprognostic (3.35e-1)" "unprognostic (4.66e-2)" "unprognostic (1.56e-2)" "unprognostic (1.14e-1)" "unprognostic (7.87e-2)" "unprognostic (5.68e-2)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.96e-1)" "prognostic favorable (3.76e-5)" "unprognostic (3.36e-2)" "prognostic favorable (5.97e-6)" "unprognostic (2.33e-1)" "unprognostic (5.09e-1)" "unprognostic (3.67e-1)" "unprognostic (2.00e-3)" 8.9 20.5 8.0 15.9 8.2 11.6 9.4 9.9 11.4 9.2 9.6 17.1 30.7 9.6 9.7 10.5 9.5 9.7 9.8 8.0 7.1 11.6 19.2 7.9 21.7 9.1 8.2 8.9 15.6 18.5 7.7 6.1 9.3 8.6 11.4 5.9 13.2 6.5 13.1 10.5 26.4 7.8 7.1 13.3 12.6 7.8 10.6 37.6 9.8 16.5 13.9 10.2 8.7 12.0 12.8 17.8 8.4 14.4 14.5 13.3 19.6 16.5 6.1 16.2 10.4 16.2 20.9 33.2 21.5 14.2 10.5 20.9 8.6 19.4 10.0 12.3 20.6 25.8 16.6 23.8 35.2 8.1 13.3 19.4 22.0 12.4 18.1 18.5 11.7 242.9 36.4 10.1 9.0 32.7 45.6 25.7 9.8 24.8 30.0 53.2 7.2 14.1 15.9 17.2 20.6 15.3 26.6 6.8 26.2 13.5 23.1 28.6 11.6 17.3 12.8 10.2 12.5 11.7 17.3 113.0 15.4 29.8 14.5 7.0 23.0 17.2 22.7 22.8 25.2 29.8 18.5 16.5 21.7 20.6 19.5 17.4 9.0 10.8 21.3 24.6 19.6 17.9 8.0 8.2 9.9 11.4 8.0 7.1 9.1 8.2 9.3 7.1 10.6 12.0 9.2 0.0 11.4 9.4 22.5 3.2 7.6 11.9 4.0 20.2 8.5 7.5 9.1 11.5 15.5 5.5 31.3 11.9 17.5 29.9 15.6 16.1 13.8 10.3 9.3 10.3 16.8 14.3 10.1 10.7 3.8 9.3 17.3 8.1 2.5 44.7 7.9 12.5 18.6 21.9 9.5 19.4 28.5 19.5 14.2 20.4 12.2 14.0 7.2 14.0 18.6 9.3 13.4 9.0 11.2 16.3 20.8 10.1 21.2 8.9 54.7 13.5 10.0 19.0 39.5 11.1 9.7 8.8 8.5 8.2 4.5 7.3 17.0 20.1 31.1 7.4 ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 524.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 364.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 210000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004303: AB_626633, HPA006035: AB_1078095" "unprognostic (4.40e-2)" "unprognostic (1.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (6.19e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (3.62e-1)" "unprognostic (3.23e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.08e-10)" "unprognostic (2.87e-2)" "unprognostic (2.00e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (8.00e-4)" 117.4 40.7 27.3 149.5 55.8 149.3 103.5 0.1 32.0 118.4 20.1 449.8 49.8 313.1 60.3 154.4 152.1 143.9 121.4 29.7 14.7 46.7 61.8 100.0 47.5 24.5 11.0 61.8 46.8 9.1 27.3 96.1 7.3 174.3 109.0 28.2 116.4 295.1 21.7 59.3 106.9 524.5 4.2 55.9 171.7 21.2 32.9 32.6 35.0 13.3 50.7 305.9 83.3 28.8 871.9 262.3 158.6 121.4 275.2 180.5 592.4 749.3 712.0 770.0 571.1 211.8 196.6 0.7 256.5 744.7 310.4 370.9 126.8 790.3 965.2 4.6 38.5 118.2 133.5 179.0 494.0 85.4 14.3 231.7 152.1 479.8 540.3 551.6 428.6 48.2 56.9 1.4 612.0 246.9 10.1 181.1 124.7 217.9 198.1 59.3 294.1 32.6 292.0 225.6 57.0 68.7 649.9 96.8 177.1 474.8 146.0 170.9 546.0 1085.2 432.8 126.9 662.5 113.8 47.8 3.9 314.4 115.7 584.4 64.6 67.5 137.1 5.7 28.8 7.1 0.1 22.7 12.4 45.5 0.2 103.9 92.2 364.2 4.5 8.9 2.0 9.6 89.2 27.3 55.8 0.1 32.0 29.7 14.7 24.5 11.0 7.3 4.2 32.9 28.8 44.7 38.5 25.1 19.6 4.0 119.3 154.9 137.4 82.0 74.7 88.6 157.6 60.3 51.5 36.0 42.3 246.0 155.3 3.0 17.2 3.9 186.8 34.0 65.8 112.8 135.5 38.5 21.9 102.7 144.9 351.8 88.9 34.1 90.2 7.6 15.9 129.5 96.6 79.5 18.5 29.7 57.3 59.0 100.9 82.1 10.7 35.8 96.4 30.2 34.7 105.1 6.0 4.1 9.0 4.3 203.7 28.0 245.6 0.6 132.6 2.4 15.3 47.8 80.8 177.5 30.0 270.6 19.4 18.4 51.8 59.8 66.9 22.7 20.9 47.0 67.1 ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736444-157876330 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007505, HPA046514" Approved Uncertain Nucleoli,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Cytosol "HPA007505: AB_1844752, HPA046514: AB_2732526" "unprognostic (6.99e-2)" "unprognostic (3.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (5.17e-4)" 20.8 10.4 17.3 12.9 12.7 1.8 18.8 14.0 15.4 28.1 17.4 16.5 10.9 24.4 32.7 11.3 17.0 24.2 19.7 26.3 12.8 26.4 22.7 17.5 8.8 13.7 12.9 21.2 10.0 8.5 10.9 17.6 13.7 15.1 12.6 6.3 18.8 15.3 21.5 13.9 10.5 34.5 12.6 8.3 14.7 5.2 16.3 7.5 40.5 13.3 8.2 20.9 15.5 11.8 6.1 13.1 14.4 18.5 65.0 70.6 18.9 43.4 71.3 33.7 36.1 10.1 13.4 0.2 18.2 45.6 32.3 16.9 10.5 22.5 36.8 43.0 8.7 25.7 7.2 14.4 54.7 2.0 28.5 89.5 41.4 69.8 84.2 42.8 38.7 6.7 9.5 6.7 45.2 11.1 0.4 0.4 21.4 8.7 21.7 4.1 19.6 5.7 45.4 24.5 12.4 14.9 17.0 9.7 64.5 22.2 5.3 7.0 54.0 50.9 16.8 25.3 17.1 4.7 3.5 0.3 52.2 1.6 58.1 2.9 1.7 0.1 0.5 1.0 0.7 0.8 4.9 1.3 1.3 0.2 1.6 0.7 0.2 1.2 1.4 1.4 6.6 1.1 17.3 12.7 14.0 15.4 26.3 12.8 13.7 12.9 13.7 12.6 16.3 11.8 9.6 9.6 9.0 22.9 1.8 9.8 7.7 12.6 12.5 10.4 8.0 9.8 12.7 11.5 12.4 7.3 0.0 8.4 1.1 4.8 5.9 9.9 1.0 5.9 12.9 17.3 4.2 1.7 34.0 17.8 5.3 20.3 8.2 6.5 5.1 4.2 18.2 13.3 7.0 3.3 34.2 4.5 24.4 13.0 8.7 2.0 20.2 7.6 3.6 106.8 5.5 6.6 2.1 42.3 22.9 17.2 4.1 15.8 6.4 13.0 3.7 15.5 13.6 2.1 13.1 16.3 19.3 0.4 2.7 4.0 7.5 10.5 4.3 3.5 4.3 8.8 ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157628864 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 31.3;brain: 10.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 26.2;Leydig cells: 31.7;Oligodendrocytes: 55.8;Proximal enterocytes: 17.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 10.9;HDLM-2: 5.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 29.7" "HPA007982, HPA011933" Uncertain "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" 31.3 2.5 3.2 0.6 6.3 0.1 6.2 1.3 3.5 0.5 0.0 4.1 4.1 0.1 0.3 0.2 0.1 0.3 0.4 6.4 10.2 0.4 2.2 0.2 0.5 1.4 1.9 3.6 1.5 0.0 2.2 0.1 1.3 0.2 3.0 0.4 0.8 0.3 0.8 0.3 3.4 0.2 0.9 0.1 2.1 0.4 6.6 0.2 0.2 0.3 0.3 0.1 0.2 3.8 1.5 0.0 0.0 0.1 10.9 0.3 0.2 0.3 0.3 0.1 0.3 1.7 0.2 0.0 0.1 0.9 0.7 0.0 0.1 0.0 0.2 5.1 0.7 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 1.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.2 0.0 0.2 0.0 0.6 0.2 0.0 0.1 0.6 1.9 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.4 0.2 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 3.2 6.3 1.3 3.5 6.4 10.2 1.4 1.9 1.3 0.9 6.6 3.8 0.5 0.0 1.1 14.7 1.4 0.6 0.7 0.9 1.8 0.8 0.9 0.3 1.9 0.0 0.9 0.0 0.0 0.2 0.3 14.3 0.0 0.2 1.9 0.4 4.9 0.7 7.8 0.0 26.2 0.2 0.8 0.9 2.6 0.5 0.0 0.4 1.1 5.9 0.1 0.0 11.0 9.2 2.0 0.0 1.3 2.9 31.7 0.1 3.6 3.7 4.3 1.8 0.0 3.5 55.8 0.4 7.6 9.1 2.9 1.8 17.7 1.1 0.2 0.3 0.0 0.6 0.8 0.4 2.4 0.7 1.4 0.3 2.5 0.4 13.5 0.5 ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 96.3" "Cell type enhanced" "Detected in many" "Adipocytes: 107.3;Distal enterocytes: 182.7;Endothelial cells: 84.7;Fibroblasts: 56.0;Hepatic stellate cells: 60.3;Paneth cells: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 19 "classical monocyte: 1.5;myeloid DC: 2.1" "Group enriched" "Detected in many" 19 "dendritic cells: 2.1;monocytes: 1.5" "Cell line enhanced" "Detected in some" "ASC diff: 61.4;ASC TERT1: 42.1;EFO-21: 61.0;HUVEC TERT2: 200.0;TIME: 161.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" 49.2 12.1 17.1 20.1 14.5 0.6 38.4 15.5 14.9 35.9 10.5 39.2 10.2 28.1 4.3 11.4 32.7 14.3 38.5 13.3 14.6 29.8 3.3 96.3 15.1 17.8 16.7 4.8 12.0 23.6 6.2 83.8 18.7 17.7 28.4 0.7 11.8 13.3 18.2 18.5 28.5 16.2 14.0 29.2 19.1 1.7 22.0 4.6 29.2 15.7 6.1 25.1 25.6 15.0 0.0 0.7 0.4 0.0 61.4 42.1 0.1 3.0 5.6 0.1 0.3 0.3 0.4 0.1 61.0 24.0 0.2 0.0 0.0 0.0 0.1 0.1 2.1 1.4 0.0 0.0 9.0 0.0 1.3 16.8 0.1 0.4 0.0 0.0 200.0 0.0 0.2 0.1 1.1 0.5 0.0 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 0.1 0.4 0.0 4.1 161.2 0.0 0.4 0.7 0.0 0.0 0.1 0.2 0.3 0.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 17.1 14.5 15.5 14.9 13.3 14.6 17.8 16.7 18.7 14.0 22.0 15.0 107.3 3.2 7.9 0.0 0.6 5.2 0.3 0.0 0.6 0.4 1.0 1.3 4.0 0.0 1.3 0.0 0.0 0.6 0.3 182.7 0.0 4.0 0.0 1.4 19.9 84.7 5.4 0.0 0.1 1.4 36.9 56.0 0.5 0.7 0.0 0.0 60.3 0.1 12.0 0.0 0.0 26.4 0.0 30.9 12.4 1.2 11.8 7.8 5.4 25.3 9.9 2.0 0.0 1.0 0.1 0.0 74.7 3.4 0.1 0.6 4.5 0.0 2.8 0.4 39.5 32.9 18.2 0.1 0.8 0.6 5.4 2.6 1.2 0.6 49.3 1.0 ACYP1 ENSG00000119640 "Acylphosphatase 1" P07311 14 75053237-75069483 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 137.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034944 Approved Approved Nucleoplasm,Cytosol NA NA 89000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Cytosol Nucleoplasm "HPA034944: AB_10669898" "prognostic favorable (1.17e-4)" "unprognostic (3.83e-3)" "unprognostic (1.92e-1)" "unprognostic (5.90e-2)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (6.14e-7)" "unprognostic (5.48e-2)" "unprognostic (4.40e-1)" "unprognostic (1.64e-2)" "unprognostic (1.37e-3)" "unprognostic (3.56e-2)" "unprognostic (4.74e-2)" "unprognostic (6.69e-3)" "unprognostic (9.39e-2)" "unprognostic (1.07e-1)" "unprognostic (5.32e-3)" 13.7 38.4 46.2 15.2 48.6 21.1 22.1 49.9 65.5 17.3 50.8 21.5 15.6 14.4 36.7 20.8 29.6 10.2 17.0 45.0 54.0 29.1 9.6 19.7 27.7 50.7 49.7 13.6 12.4 21.1 36.5 15.3 51.8 17.3 26.9 44.0 15.8 15.0 34.0 35.0 21.1 15.6 46.6 16.5 19.3 26.9 50.4 39.7 30.1 21.1 28.1 16.1 17.6 56.0 78.9 43.1 60.9 37.4 24.5 26.6 32.6 44.7 17.2 45.5 63.5 42.8 86.9 86.5 26.4 18.2 25.7 68.1 39.9 19.1 73.8 127.8 49.3 57.6 123.6 32.1 14.3 36.6 56.8 14.9 27.7 61.5 30.0 28.8 60.0 80.9 45.2 103.0 60.0 52.3 82.7 67.7 18.6 67.6 40.8 64.7 80.8 41.2 62.2 39.0 112.0 44.5 29.5 20.8 74.2 29.1 44.5 35.4 27.3 29.5 55.6 61.3 48.4 23.8 52.4 94.6 46.1 42.5 32.8 5.3 2.8 17.5 10.9 6.2 12.7 13.7 18.3 12.9 5.1 14.1 15.4 14.5 1.2 14.0 10.5 10.3 24.6 6.7 46.2 48.6 49.9 65.5 45.0 54.0 50.7 49.7 51.8 46.6 50.4 56.0 18.5 6.4 9.1 17.0 18.2 28.7 44.4 54.1 30.1 38.6 20.8 24.0 21.2 31.5 28.9 66.2 12.5 27.3 18.7 24.5 39.2 20.6 31.6 89.2 18.4 26.5 30.1 47.5 17.8 18.7 33.7 22.7 13.7 17.8 12.0 19.8 10.4 5.7 22.3 43.7 25.0 25.2 73.2 6.6 11.7 11.0 16.8 12.3 39.2 15.9 10.1 23.2 16.5 16.1 44.4 20.2 20.6 16.6 16.9 20.2 16.7 22.3 137.9 32.4 26.3 11.1 31.5 89.8 14.1 23.8 24.0 13.7 22.3 20.4 33.8 34.4 ACYP2 ENSG00000170634 "Acylphosphatase 2" P14621 2 53970838-54305300 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.4;tongue: 163.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 162.6;Excitatory neurons: 158.8;Oligodendrocytes: 180.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035301 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA035301: AB_10670291" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (3.40e-1)" "unprognostic (2.16e-1)" "unprognostic (6.90e-3)" "unprognostic (6.21e-2)" "unprognostic (2.03e-3)" "unprognostic (3.17e-1)" "unprognostic (5.22e-2)" "unprognostic (7.83e-3)" "unprognostic (3.64e-3)" "unprognostic (1.16e-1)" "unprognostic (6.66e-2)" "unprognostic (2.13e-1)" "unprognostic (1.97e-1)" "unprognostic (3.24e-1)" "unprognostic (2.24e-2)" 19.5 42.8 64.9 5.4 72.9 7.1 15.7 74.8 85.4 10.6 61.5 14.3 7.4 11.5 12.8 10.4 11.6 8.5 63.4 63.9 72.8 14.5 28.0 10.6 10.9 69.5 68.8 9.3 12.7 13.6 26.2 6.5 70.3 14.4 5.3 24.1 15.2 9.2 207.4 9.9 9.0 7.9 70.4 12.7 12.9 10.2 70.4 10.7 12.6 163.2 8.4 14.0 10.7 76.9 11.7 5.9 6.0 4.4 23.7 17.3 3.7 11.5 9.7 8.3 7.3 1.5 7.1 21.5 33.0 12.6 7.8 8.5 3.3 10.8 7.4 14.4 13.1 13.4 6.3 16.3 8.5 12.7 6.3 13.6 19.3 5.6 9.5 15.2 3.9 9.8 5.5 11.5 17.9 7.6 7.5 17.0 5.9 8.4 6.7 5.4 4.7 12.2 18.8 10.6 17.6 10.0 17.4 10.0 5.7 1.9 3.4 13.2 10.9 11.5 10.6 3.5 11.1 21.4 12.5 10.2 16.3 24.3 12.4 41.2 14.0 26.1 16.9 13.0 15.4 29.0 16.6 16.1 20.3 26.9 20.1 16.4 11.5 18.6 13.5 33.4 16.3 11.3 64.9 72.9 74.8 85.4 63.9 72.8 69.5 68.8 70.3 70.4 70.4 76.9 21.7 16.0 17.9 84.9 30.6 20.5 41.9 52.8 18.8 15.5 49.7 65.7 162.6 34.3 32.0 18.4 10.4 13.6 27.9 24.5 62.6 24.3 86.8 29.5 23.6 23.1 30.6 14.5 158.8 38.1 6.1 21.0 26.0 19.5 19.7 17.6 30.7 74.2 31.9 28.6 134.1 21.9 36.7 40.0 28.5 64.7 13.4 25.4 23.2 59.0 26.1 90.1 24.7 67.8 180.1 29.9 18.8 30.9 36.4 27.4 29.1 55.6 32.2 31.6 52.6 30.8 30.0 22.9 9.8 28.9 21.3 10.3 22.7 29.7 18.6 45.0 ADA2 "ADGF, CECR1, IDGFL" ENSG00000093072 "Adenosine deaminase 2" Q9NZK5 22 17178790-17258235 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 106.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.6;Glandular and luminal cells: 22.0;Hofbauer cells: 57.6;Macrophages: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.7;EFO-21: 21.4;HUVEC TERT2: 24.0;Karpas-707: 44.9;MOLT-4: 38.9;U-266/70: 23.8;U-937: 39.6" "Low region specificity" "Detected in all" HPA007888 Uncertain "Secreted to blood" NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA007888: AB_1078495" "unprognostic (1.03e-3)" "unprognostic (2.00e-3)" "unprognostic (6.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-2)" "unprognostic (7.01e-3)" "unprognostic (4.48e-2)" "unprognostic (3.09e-3)" "unprognostic (3.80e-2)" "prognostic favorable (9.26e-4)" "prognostic favorable (8.91e-4)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (4.86e-3)" "unprognostic (1.96e-2)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" 14.0 11.3 8.3 39.4 9.9 22.8 17.6 10.6 7.9 22.0 20.5 28.3 18.1 19.9 2.7 12.0 51.5 32.1 39.6 7.8 10.9 14.5 21.1 54.9 47.3 16.3 11.4 12.1 13.9 5.4 22.5 15.2 14.7 15.4 34.3 11.0 15.6 17.1 3.4 4.7 26.1 23.4 13.7 106.3 19.6 18.4 12.9 53.7 16.9 4.3 60.7 34.7 6.5 21.1 0.0 0.0 6.4 0.0 0.2 0.8 0.3 2.3 0.1 0.0 0.0 0.0 23.7 6.0 21.4 7.2 0.0 0.5 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.1 4.0 0.3 0.3 11.3 0.1 0.0 0.1 0.1 24.0 9.0 0.1 44.9 0.9 0.0 38.9 1.1 17.8 0.0 0.1 1.2 0.0 6.5 0.0 9.3 10.9 0.1 0.1 0.0 0.0 19.1 0.2 9.7 3.0 0.1 0.2 0.0 0.0 23.8 2.3 1.7 0.0 39.6 0.0 17.5 212.9 11.3 34.6 204.9 26.8 25.8 27.4 34.1 139.1 19.7 31.6 32.4 10.5 44.9 176.1 57.4 17.2 170.7 8.3 9.9 10.6 7.9 7.8 10.9 16.3 11.4 14.7 13.7 12.9 21.1 8.7 0.0 16.8 0.0 7.2 0.0 0.0 0.0 0.0 0.0 5.1 4.2 0.0 0.0 11.2 5.5 0.0 0.4 13.7 0.0 7.9 1.7 0.0 27.6 6.6 2.2 0.0 0.0 0.0 5.2 0.9 2.1 0.0 22.0 5.1 12.6 0.0 0.0 57.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 12.4 0.0 0.0 3.1 15.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.8 8.2 3.1 0.0 0.0 ADAM10 "CD156C, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588809-58749791 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 377.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 296.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 690000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavorable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" 14.9 8.7 11.4 19.0 18.6 18.7 15.2 20.2 15.0 16.0 9.7 22.2 15.9 16.3 7.7 15.4 13.9 18.9 12.1 12.2 12.7 18.0 16.1 21.0 22.2 18.2 17.6 14.1 8.8 7.9 8.2 29.0 17.5 25.2 17.2 10.8 9.3 12.2 6.1 16.9 17.5 13.3 13.7 29.0 20.3 8.5 15.5 42.7 28.6 7.1 16.4 28.0 10.4 25.2 48.4 88.5 27.6 31.2 34.8 49.8 70.0 39.0 116.0 28.6 39.1 39.9 62.6 22.7 118.0 35.2 49.2 95.9 16.8 43.5 37.0 30.1 19.3 38.7 35.1 42.1 40.8 25.0 103.8 44.4 30.0 19.9 29.2 41.1 55.6 45.0 24.5 57.9 50.4 15.4 89.5 32.0 40.2 15.4 14.6 36.4 91.6 57.1 66.6 121.4 29.9 20.3 44.0 52.8 73.1 60.0 30.4 55.0 41.4 37.1 41.2 296.6 39.6 30.7 70.7 23.5 54.1 50.8 67.3 30.9 36.2 19.2 12.8 41.1 19.2 8.3 12.7 11.6 23.6 9.6 12.7 10.8 51.5 17.7 48.6 10.2 18.2 25.8 11.4 18.6 20.2 15.0 12.2 12.7 18.2 17.6 17.5 13.7 15.5 25.2 60.1 83.3 50.8 83.2 37.9 26.6 30.7 33.3 33.0 22.7 61.6 30.9 40.0 30.0 46.7 80.9 27.1 35.6 69.4 79.0 1.9 56.0 21.2 39.5 56.4 72.5 36.1 20.8 106.1 31.8 57.8 36.1 53.0 74.0 30.3 31.5 71.4 36.2 63.8 45.4 96.2 43.6 36.7 90.1 28.9 19.4 18.0 77.9 46.2 147.1 69.0 30.6 44.3 75.9 377.6 48.9 48.1 17.0 51.0 89.1 45.1 23.7 41.2 33.4 13.1 34.4 42.8 20.3 17.8 39.5 22.3 26.5 51.3 34.1 39.5 83.9 ADAM12 "MCMPMltna, MLTN" ENSG00000148848 "ADAM metallopeptidase domain 12" O43184 10 126012381-126388455 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 166.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 102.2;Extravillous trophoblasts: 400.8;Oligodendrocyte precursor cells: 99.0;Syncytiotrophoblasts: 129.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "MAIT T-cell: 6.1" "Lineage enriched" "Detected in single" 62 "T-cells: 6.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 154.2;hTEC/SVTERT24-B: 94.3;U-2197: 93.2;U-251 MG: 86.2;U-87 MG: 70.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030866, HPA030867, HPA030868" Enhanced Supported "Plasma membrane" "Secreted in female reproductive system" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA030866: AB_2673636, HPA030867: AB_10602428, HPA030868: AB_2673638" "unprognostic (3.35e-1)" "unprognostic (1.05e-3)" "unprognostic (3.52e-2)" "unprognostic (2.47e-2)" "unprognostic (3.34e-2)" "unprognostic (2.16e-1)" "unprognostic (2.91e-6)" "unprognostic (2.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.53e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.39e-14)" "unprognostic (3.11e-3)" "unprognostic (9.06e-3)" "unprognostic (4.70e-3)" "unprognostic (3.47e-3)" 11.4 0.1 2.0 6.0 4.0 0.1 4.6 1.6 2.1 18.2 3.5 0.4 0.2 6.3 0.0 0.4 0.2 11.8 0.7 1.0 2.5 1.0 0.2 1.3 3.2 6.0 2.7 8.8 0.5 0.1 1.1 166.5 3.1 0.3 0.6 0.3 1.1 0.0 0.1 0.4 0.5 4.3 1.8 1.6 0.5 0.9 10.4 1.8 0.3 0.0 3.5 11.6 0.5 3.0 16.8 2.5 6.5 0.1 18.7 38.3 0.0 42.7 3.5 14.2 35.5 0.0 0.0 0.0 0.0 154.2 30.0 0.0 0.2 1.4 15.5 1.9 0.6 0.2 25.1 0.0 2.9 0.0 33.2 47.0 0.0 94.3 2.9 27.1 0.0 0.0 0.0 0.2 11.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 4.8 4.4 0.4 44.1 0.5 28.4 5.0 0.0 0.7 2.5 0.1 0.1 0.0 50.9 16.9 93.2 86.2 0.0 0.5 0.0 70.7 0.1 32.3 0.0 0.0 0.0 0.3 0.0 6.1 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 2.0 4.0 1.6 2.1 1.0 2.5 6.0 2.7 3.1 1.8 10.4 3.0 0.5 0.0 1.9 22.5 0.3 1.5 0.4 3.0 0.0 2.1 1.7 3.6 2.3 0.0 0.5 0.0 102.2 14.0 0.5 0.7 0.0 8.0 10.9 10.7 16.6 1.6 0.0 0.0 7.4 1.1 400.8 34.5 0.5 1.8 49.5 7.8 2.5 0.2 15.5 6.7 19.0 1.0 4.1 0.6 3.1 1.7 16.8 0.8 1.8 14.0 9.0 3.3 1.0 99.0 52.2 2.2 0.1 0.7 0.3 1.0 0.7 0.4 6.5 30.5 0.0 5.1 13.4 6.0 5.0 0.0 0.6 129.2 4.7 28.1 0.9 0.5 ADAM15 MDC15 ENSG00000143537 "ADAM metallopeptidase domain 15" Q13444 1 155050566-155062775 "Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.5;Extravillous trophoblasts: 172.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 39.1;intermediate monocyte: 26.5;myeloid DC: 64.0" "Group enriched" "Detected in all" 5 "dendritic cells: 64.0;monocytes: 39.1" "Cell line enhanced" "Detected in many" "PC-3: 329.5;RPMI-8226: 361.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011633, HPA072878" Uncertain Uncertain Vesicles NA NA 640000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA011633: AB_1844574, HPA072878: " "unprognostic (6.35e-3)" "unprognostic (1.51e-1)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (5.83e-5)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (2.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.64e-9)" "unprognostic (3.35e-2)" "unprognostic (6.20e-2)" "unprognostic (2.04e-2)" "unprognostic (7.40e-2)" 70.1 18.5 12.5 21.4 16.0 34.1 64.7 16.9 13.9 40.3 7.1 38.3 16.4 42.5 7.6 79.1 41.5 21.6 63.1 10.5 13.8 32.4 15.1 50.0 10.0 20.2 15.1 25.5 25.5 30.0 14.1 39.1 16.8 40.0 23.8 3.4 45.3 16.7 22.7 107.9 31.3 38.6 17.3 28.8 44.2 4.9 17.1 7.3 31.6 32.4 13.6 38.9 57.3 18.0 112.0 35.0 7.0 153.2 54.9 45.6 66.3 48.2 60.9 60.1 40.5 25.9 63.3 30.9 210.7 63.5 26.7 135.9 34.5 147.9 15.8 14.3 44.9 7.6 63.1 25.3 95.5 63.4 7.9 48.7 153.8 60.5 86.6 82.6 274.7 9.3 11.9 124.8 45.2 64.7 0.5 47.1 21.6 193.4 329.5 10.0 20.5 361.8 43.7 29.7 20.8 44.7 105.2 131.2 41.8 10.7 194.8 38.9 205.1 58.6 24.6 58.9 54.1 13.9 11.7 13.7 42.7 47.6 65.4 0.0 39.1 0.8 9.5 26.5 6.5 2.0 4.7 5.6 64.0 2.1 2.0 2.5 1.4 1.6 6.2 5.3 8.9 22.8 12.5 16.0 16.9 13.9 10.5 13.8 20.2 15.1 16.8 17.3 17.1 18.0 164.5 3.2 6.7 8.8 6.6 48.9 30.4 81.6 47.8 9.7 34.6 20.7 11.5 35.8 38.3 9.2 29.2 13.0 8.1 100.4 0.0 33.4 1.7 13.3 9.2 120.8 12.7 4.6 8.1 25.5 172.4 19.8 85.6 15.4 1.3 8.5 62.2 19.9 31.7 6.7 9.8 80.7 18.3 65.0 43.6 1.3 17.4 27.2 14.2 15.9 28.8 8.8 13.4 9.0 16.8 42.1 50.9 18.0 8.0 55.2 47.4 2.6 22.9 17.0 13.1 15.7 14.5 0.8 6.4 91.2 57.1 17.8 8.6 2.7 76.9 40.0 ADAM18 "ADAM27, tMDCIII" ENSG00000168619 "ADAM metallopeptidase domain 18" Q9Y3Q7 8 39584489-39730065 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 74 "testis: 9.2" "Cell type enhanced" "Detected in some" "Early spermatids: 63.5;Late spermatids: 26.8;Spermatocytes: 141.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (2.10e-4)" "unprognostic (1.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 63.5 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 26.8 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 141.1 3.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 ADAM22 MDC2 ENSG00000008277 "ADAM metallopeptidase domain 22" Q9P0K1 7 87934143-88202889 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 77.2" "Group enriched" "Detected in many" 4 "Excitatory neurons: 286.7;Inhibitory neurons: 304.9;Oligodendrocyte precursor cells: 184.0;Oligodendrocytes: 125.6" "Cancer enhanced" "Detected in many" "glioma: 4.0" "Region enhanced" "Detected in all" "cerebellum: 77.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 81.8;SH-SY5Y: 76.9;U-266/84: 33.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050325, CAB079064" Supported Approved "Cell Junctions" "Intracellular and membrane" NA NA 180000 "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "CAB079064: , HPA050325: AB_2681087" "unprognostic (1.20e-2)" "unprognostic (8.61e-2)" "unprognostic (3.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.89e-2)" "unprognostic (3.09e-1)" "unprognostic (7.84e-3)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-1)" "unprognostic (3.47e-2)" "unprognostic (4.13e-2)" "unprognostic (2.77e-1)" "unprognostic (1.61e-4)" "unprognostic (4.70e-2)" 2.0 9.1 7.2 0.9 9.2 0.9 1.3 77.2 30.6 6.0 0.0 1.5 0.6 4.6 8.5 0.8 2.4 2.5 2.1 12.2 8.9 3.8 0.2 1.2 2.2 14.4 5.6 3.9 1.0 2.1 3.4 0.3 14.7 11.0 1.4 10.3 0.7 5.1 2.5 1.0 1.1 3.5 2.7 2.0 0.6 1.9 13.8 2.5 3.2 1.2 1.1 1.6 2.6 12.3 2.5 0.7 4.8 5.8 1.4 0.3 3.5 0.1 0.5 0.4 0.5 5.1 8.3 7.4 2.0 0.0 3.5 0.2 7.0 0.1 0.1 20.5 9.0 5.6 5.4 1.5 0.1 6.9 0.1 0.7 0.0 0.1 0.3 6.3 0.5 8.1 0.2 81.8 0.2 6.7 8.9 1.4 11.6 0.6 2.6 5.2 18.8 10.7 0.1 4.1 25.9 76.9 4.1 0.1 0.8 3.7 3.5 0.8 0.1 4.8 3.3 0.9 3.6 18.8 33.2 5.9 4.1 14.2 7.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.0 0.0 7.2 9.2 77.2 30.6 12.2 8.9 14.4 5.6 14.7 2.7 13.8 12.3 2.4 0.0 2.0 45.7 1.1 0.5 1.7 0.0 2.8 28.4 0.5 0.6 3.1 0.0 0.6 1.8 22.9 0.4 1.9 0.3 1.9 0.0 7.8 2.2 6.9 1.5 1.2 1.3 286.7 0.0 0.1 4.8 1.1 3.3 0.0 0.7 0.7 0.0 0.1 15.2 304.9 0.6 0.0 0.3 0.6 1.5 2.5 0.2 1.8 18.7 0.0 1.4 2.1 184.0 125.6 0.0 3.1 2.6 0.9 0.4 0.3 1.0 0.8 10.9 0.0 2.9 3.2 0.8 1.9 0.4 0.4 0.0 2.2 3.7 1.3 0.3 ADAM28 "ADAM23, eMDCII, MDC-Lm, MDC-Ls" ENSG00000042980 "ADAM metallopeptidase domain 28" Q9UKQ2 8 24294069-24359014 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 357.5;stomach 1: 110.3" "Cell type enhanced" "Detected in many" "B-cells: 240.9;Club cells: 62.9;Gastric mucus-secreting cells: 141.7;Microglial cells: 233.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 71.6;naive B-cell: 87.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "CAPAN-2: 27.8;OE19: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074034 Enhanced Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" Mitochondria "HPA074034: AB_2686654" "unprognostic (4.23e-2)" "unprognostic (1.01e-2)" "unprognostic (2.06e-2)" "prognostic favorable (3.17e-4)" "unprognostic (2.89e-1)" "unprognostic (2.55e-2)" "unprognostic (5.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-1)" "unprognostic (1.35e-2)" "unprognostic (3.77e-3)" "unprognostic (7.77e-2)" "unprognostic (3.97e-3)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" 2.2 2.2 5.9 24.7 4.6 9.3 3.9 7.1 5.0 16.1 4.0 14.3 8.8 6.9 357.5 2.8 12.3 40.2 1.0 5.8 8.8 5.1 1.2 3.9 26.7 12.0 9.3 2.3 3.5 1.1 18.5 3.7 11.7 5.3 12.1 1.3 15.9 5.7 0.3 3.3 24.7 2.9 9.8 19.9 110.3 0.7 10.1 5.1 1.9 0.4 32.3 11.3 1.7 18.6 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 1.1 27.8 0.3 0.8 0.0 0.9 0.1 0.0 0.8 0.1 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.7 0.7 8.8 0.1 0.1 0.0 0.4 0.6 0.8 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.3 0.1 0.1 1.2 2.5 0.1 2.1 1.0 0.2 42.4 2.5 18.5 0.0 0.6 0.0 71.6 0.1 0.0 21.0 87.0 0.1 0.0 4.3 2.7 0.2 1.1 0.1 2.5 5.9 4.6 7.1 5.0 5.8 8.8 12.0 9.3 11.7 9.8 10.1 18.6 1.5 3.2 6.0 0.7 240.9 0.9 3.0 36.9 0.0 0.1 2.3 2.2 2.0 28.6 62.9 3.7 0.0 0.4 9.9 0.7 0.0 7.9 1.3 7.6 1.0 3.7 0.0 8.2 4.3 3.5 8.7 3.9 141.7 18.4 2.5 0.0 0.0 0.0 9.4 0.0 2.7 0.4 28.5 12.3 30.9 1.8 0.6 46.4 5.4 233.3 7.8 0.1 23.7 3.5 1.6 55.7 0.1 0.4 43.3 1.5 0.6 4.4 13.1 0.1 6.6 0.0 1.1 0.4 0.2 0.7 0.6 0.5 9.0 6.4 1.3 7.6 ADAM29 "CT73, svph1" ENSG00000168594 "ADAM metallopeptidase domain 29" Q9UKF5 4 174829668-174978180 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 62 "testis: 41.1" "Group enriched" "Detected in some" 25 "Early spermatids: 429.2;Late spermatids: 280.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.40e-3)" "unprognostic (2.03e-2)" "unprognostic (4.72e-3)" "unprognostic (4.93e-2)" "unprognostic (1.16e-6)" "unprognostic (1.35e-1)" "unprognostic (1.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 429.2 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 280.6 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 14.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADAM32 ENSG00000197140 "ADAM metallopeptidase domain 32" Q8TC27 8 39106990-39284917 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 27.4" "Cell type enhanced" "Detected in many" "Early spermatids: 189.0;Excitatory neurons: 37.3;Late spermatids: 50.5;Spermatocytes: 99.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.0;MCF7: 1.1;U-2 OS: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA044156, HPA062151" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA044156: AB_10796798, HPA062151: AB_2684699" "unprognostic (2.13e-1)" "unprognostic (6.92e-2)" "unprognostic (4.63e-3)" "unprognostic (8.99e-2)" "unprognostic (1.48e-1)" "unprognostic (1.52e-2)" "unprognostic (5.66e-3)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-1)" "unprognostic (3.38e-2)" "unprognostic (1.13e-7)" "unprognostic (3.42e-1)" "unprognostic (4.90e-2)" "unprognostic (8.34e-3)" "unprognostic (7.82e-2)" 1.0 1.0 1.0 0.2 0.9 0.4 1.0 3.2 1.5 0.6 0.0 0.5 0.0 0.4 0.6 0.2 0.5 0.4 0.7 0.9 1.3 0.2 0.0 0.3 0.1 0.1 0.5 0.6 1.8 0.0 0.4 0.1 0.4 0.6 0.4 0.9 0.5 0.3 0.2 0.7 0.2 0.1 0.1 0.7 0.3 27.4 1.0 0.0 0.3 0.1 0.1 0.5 0.4 1.3 0.2 0.4 0.0 0.2 0.6 0.0 0.0 0.4 0.1 0.4 0.2 0.1 0.9 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.2 0.5 1.1 0.1 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.7 1.3 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 1.0 0.9 3.2 1.5 0.9 1.3 0.1 0.5 0.4 0.1 1.0 1.3 1.0 0.0 0.0 11.8 0.0 0.9 1.1 0.7 0.6 8.2 2.5 2.3 1.7 1.5 0.4 1.8 18.8 0.3 0.1 0.4 0.0 0.4 189.0 5.7 3.6 1.0 4.2 0.0 37.3 1.3 0.2 2.4 0.0 9.8 0.0 3.3 0.7 0.4 0.5 0.0 29.8 1.1 0.0 0.0 1.0 50.5 2.8 0.6 0.0 9.4 0.1 1.0 0.0 18.6 17.6 2.8 0.1 3.0 0.1 1.7 0.0 0.2 1.4 3.8 0.0 3.4 0.9 99.9 2.9 0.5 0.0 0.1 0.2 3.7 1.4 1.5 ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 40.8;Fibroblasts: 45.2;Leydig cells: 22.7;Microglial cells: 18.7;Smooth muscle cells: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 82.4;ASC TERT1: 104.9;BJ: 38.5;BJ hTERT+: 64.7;fHDF/TERT166: 38.9;U-2197: 50.9" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" 53.3 3.8 7.8 10.5 8.5 0.1 47.4 5.8 12.3 280.4 8.4 157.2 11.0 151.8 19.0 31.6 106.9 32.8 26.7 6.7 9.3 3.9 2.0 18.0 6.2 16.0 8.0 58.7 6.0 0.5 6.9 12.7 16.4 87.0 12.1 1.0 19.6 57.5 9.1 22.0 43.4 53.0 5.9 8.3 44.8 22.5 6.9 0.9 18.4 14.1 2.2 125.4 159.0 6.2 0.0 0.0 0.2 0.0 82.4 104.9 0.2 38.5 64.7 11.2 21.3 0.1 0.0 0.0 0.2 38.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 13.0 0.0 0.0 18.2 0.0 4.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 2.8 0.2 2.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 0.2 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 8.5 5.8 12.3 6.7 9.3 16.0 8.0 16.4 5.9 6.9 6.2 3.9 0.0 0.0 7.2 0.1 5.5 0.1 0.0 0.6 0.0 0.3 0.3 3.3 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.5 1.8 40.8 2.4 0.0 0.0 1.3 0.0 0.1 45.2 2.6 1.2 0.0 3.1 1.8 0.0 0.5 0.0 11.4 0.0 0.0 0.3 8.8 0.8 22.7 0.8 3.6 18.7 0.0 2.2 0.0 8.0 0.1 0.0 0.0 10.1 0.0 0.2 0.0 0.9 0.0 0.1 6.6 6.8 17.1 0.7 0.5 0.3 3.1 0.5 0.7 0.0 0.0 0.1 ADAM7 "EAPI, GP-83" ENSG00000069206 "ADAM metallopeptidase domain 7" Q9H2U9 8 24440930-24526970 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 237 "epididymis: 3726.4" "Cell type enriched" "Detected in some" 7 "Early spermatids: 128.3" "Group enriched" "Detected in some" 16 "prostate cancer: 1.0;renal cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 30 "BEWO: 2.4;NB-4: 6.1;RPMI-8226: 1.7;SH-SY5Y: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA008879 Enhanced "Intracellular and membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA008879: AB_10601789" "unprognostic (1.03e-3)" "unprognostic (3.96e-4)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 3726.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.8 0.0 0.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 128.3 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 16.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADAM8 "CD156, CD156A, MS2" ENSG00000151651 "ADAM metallopeptidase domain 8" P78325 10 133262420-133276868 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.6;lymphoid tissue: 48.5" "Cell type enhanced" "Detected in many" "dendritic cells: 54.7;Extravillous trophoblasts: 96.4;Langerhans cells: 124.9;monocytes: 81.3;NK-cells: 82.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 21.2" "Group enriched" "Detected in many" 5 "basophil: 107.4;eosinophil: 259.0;neutrophil: 139.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 259.0" "Cell line enhanced" "Detected in many" "A-431: 60.0;BEWO: 81.8;CAPAN-2: 70.4;HaCaT: 69.8;HDLM-2: 45.9;U-87 MG: 34.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA064637 Approved "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA064637: AB_2685306" "unprognostic (8.24e-2)" "unprognostic (6.07e-3)" "unprognostic (1.27e-3)" "unprognostic (5.18e-2)" "unprognostic (8.26e-2)" "unprognostic (6.47e-2)" "unprognostic (5.59e-2)" "unprognostic (2.22e-1)" "unprognostic (2.57e-1)" "unprognostic (1.94e-3)" "unprognostic (3.37e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (3.99e-10)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.28e-1)" "unprognostic (9.32e-2)" 5.6 2.4 2.1 22.1 2.3 68.6 2.7 1.4 21.2 4.2 1.7 3.6 5.8 2.2 2.1 3.5 6.0 5.1 2.5 1.8 1.8 4.7 8.4 21.5 11.6 3.2 1.9 3.0 4.3 0.3 3.6 3.1 4.4 4.5 1.6 1.5 4.2 1.1 1.2 3.2 11.3 2.1 1.6 48.5 11.5 2.6 5.9 4.0 3.8 1.7 8.2 11.9 3.2 3.4 60.0 1.7 0.5 0.9 0.4 0.1 81.8 0.7 1.4 0.3 0.4 4.6 70.4 1.0 1.7 0.1 0.5 69.8 0.2 11.9 0.1 45.9 1.0 0.8 0.5 0.0 0.7 3.6 15.9 0.2 1.1 0.6 1.0 3.7 0.1 0.5 3.2 2.4 0.0 4.8 0.2 20.2 0.3 7.1 1.7 0.4 0.7 6.6 0.8 1.4 0.1 0.8 0.4 0.2 1.0 1.1 1.0 2.0 1.7 0.0 1.5 0.6 1.0 3.4 2.2 0.6 34.5 2.0 0.2 107.4 24.8 259.0 22.2 9.2 15.9 10.2 14.8 21.4 37.2 5.6 5.6 8.2 139.4 24.7 9.4 0.7 16.9 25.2 2.1 2.3 1.4 21.2 1.8 1.8 3.2 1.9 4.4 1.6 5.9 3.4 1.3 3.2 10.5 3.3 23.2 7.8 6.6 14.3 0.0 4.3 2.2 1.8 2.4 2.8 9.5 0.0 8.4 7.7 54.7 0.3 1.9 3.1 1.0 1.5 0.9 1.7 0.0 5.7 3.5 2.7 96.4 2.4 6.1 2.1 12.6 1.1 2.5 2.4 23.3 0.0 3.0 0.6 2.0 8.8 124.9 0.4 0.9 33.9 7.2 0.0 81.3 0.2 82.4 2.0 2.9 39.1 0.1 0.0 20.7 11.0 0.3 0.5 10.0 5.1 0.0 0.8 1.0 1.5 0.8 0.6 6.5 20.0 39.4 0.2 0.5 42.5 ADAM9 "CORD9, KIAA0021, MCMP, MDC9, Mltng" ENSG00000168615 "ADAM metallopeptidase domain 9" Q13443 8 38996754-39105445 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 179.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004000 Approved "Endoplasmic reticulum,Vesicles" "Secreted - unknown location" NA NA 740000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Endoplasmic reticulum" "HPA004000: AB_1844584" "prognostic unfavorable (1.14e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.32e-3)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.21e-6)" "unprognostic (5.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.83e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.80e-1)" "unprognostic (5.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-2)" 34.2 28.0 7.1 28.8 8.2 2.1 21.5 8.5 8.3 34.8 11.4 32.9 24.5 29.7 15.2 29.7 19.3 47.1 32.1 6.0 8.4 34.9 13.5 51.4 9.7 10.2 7.5 16.8 12.7 52.5 7.8 47.4 9.0 34.9 41.7 18.5 54.9 34.8 24.1 16.1 23.0 51.6 9.4 24.0 44.2 11.1 10.6 5.9 39.9 25.0 13.2 56.1 24.3 11.5 188.3 163.6 63.5 32.6 117.2 374.0 67.0 259.6 382.4 191.7 177.9 82.7 147.1 10.1 86.1 247.2 156.7 79.5 30.8 249.7 373.2 6.9 21.5 12.1 102.8 73.0 226.4 8.9 19.1 287.5 139.2 193.3 212.7 341.0 268.9 15.2 21.5 53.2 406.2 25.0 7.2 4.4 8.3 175.2 46.7 3.8 106.3 27.6 299.3 62.4 6.4 11.5 78.4 90.9 57.8 72.9 67.3 12.0 374.2 109.9 97.9 213.9 124.1 12.9 29.5 7.7 175.8 12.0 72.1 0.3 4.0 0.5 0.1 1.3 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.1 0.5 0.8 0.6 0.3 0.1 0.9 7.1 8.2 8.5 8.3 6.0 8.4 10.2 7.5 9.0 9.4 10.6 11.5 14.4 48.1 37.0 16.0 3.8 35.9 66.6 78.3 26.7 19.3 23.4 9.8 49.7 24.3 82.1 35.0 20.9 24.1 8.9 44.4 3.9 90.2 14.4 42.1 35.3 20.5 10.7 2.5 47.5 115.4 85.1 42.0 80.5 82.1 5.1 26.4 25.0 7.5 125.9 5.0 38.0 32.2 44.7 60.2 44.8 7.8 28.6 54.7 21.4 33.7 21.8 17.5 1.0 30.7 26.7 179.4 30.6 24.8 5.2 108.7 24.9 41.1 51.9 25.1 13.1 31.3 31.9 4.3 2.5 20.2 21.5 34.3 5.6 11.2 32.7 103.8 ADAMDEC1 M12.219 ENSG00000134028 "ADAM like decysin 1" O15204 8 24384285-24406013 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 424.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 14.8;Kupffer cells: 12.9;Macrophages: 25.5;monocytes: 5.2" "Cancer enhanced" "Detected in all" "testis cancer: 16.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 8 "U-266/70: 10.7;U-266/84: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 28000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.17e-2)" "unprognostic (1.80e-2)" "unprognostic (4.15e-3)" "unprognostic (3.60e-1)" "unprognostic (6.21e-2)" "unprognostic (3.84e-3)" "unprognostic (2.12e-1)" "unprognostic (2.90e-1)" "unprognostic (1.61e-1)" "unprognostic (5.99e-3)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (1.74e-2)" "unprognostic (2.06e-1)" "unprognostic (1.35e-2)" "unprognostic (3.66e-2)" "unprognostic (8.23e-2)" 0.6 0.5 0.0 52.1 0.0 0.3 0.6 0.0 0.8 0.4 0.0 215.4 189.4 0.9 0.2 0.9 0.1 3.2 0.4 0.1 0.0 0.2 0.1 1.6 73.3 0.3 0.0 0.1 0.2 0.0 0.0 7.8 0.3 0.8 311.5 0.0 0.7 0.4 0.0 0.4 424.9 11.6 0.0 5.8 5.9 0.3 0.4 5.7 0.3 0.0 27.2 20.6 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 10.7 2.7 0.0 0.0 0.0 0.0 0.0 0.7 1.9 0.0 0.8 0.0 1.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.3 0.0 0.4 0.2 0.0 0.0 0.0 0.0 2.2 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.1 0.0 0.0 12.9 2.0 0.0 0.0 25.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.1 ADAMTS1 "C3-C5, KIAA1346, METH1" ENSG00000154734 "ADAM metallopeptidase with thrombospondin type 1 motif 1" Q9UHI8 21 26835755-26845409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 314.4" "Cell type enhanced" "Detected in many" "Adipocytes: 365.2;Endometrial stromal cells: 235.3;Endothelial cells: 275.9;Extravillous trophoblasts: 240.8;Fibroblasts: 243.9;Sertoli cells: 210.4;Smooth muscle cells: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "gdT-cell: 4.5;NK-cell: 6.6" "Group enriched" "Detected in many" 56 "NK-cells: 6.6;T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 382.0;BJ: 451.4;hTEC/SVTERT24-B: 250.0;hTERT-HME1: 248.2;LHCN-M2: 295.3;RPTEC TERT1: 343.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 35.6" "CAB016394, HPA031498" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 4100000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB016394: AB_626637, HPA031498: AB_2673907" "unprognostic (6.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.03e-1)" "unprognostic (3.28e-1)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "unprognostic (9.70e-3)" "unprognostic (8.27e-3)" "unprognostic (1.12e-1)" "unprognostic (6.76e-2)" "unprognostic (1.57e-1)" 234.6 46.4 22.2 71.3 24.9 1.4 94.1 20.8 28.9 87.4 22.3 54.6 8.7 97.1 9.0 82.6 161.2 111.8 95.9 21.5 23.5 76.0 39.0 79.7 10.1 24.8 25.5 314.4 29.4 18.5 25.5 245.1 25.2 88.2 59.3 15.6 19.2 13.9 48.9 21.9 44.6 162.6 25.3 13.9 56.0 8.2 26.4 12.2 50.1 40.3 5.4 143.1 50.6 30.5 0.1 0.0 6.8 0.1 382.0 104.9 21.8 451.4 199.6 90.4 61.1 0.0 0.0 0.0 29.5 120.1 2.0 9.2 4.6 23.6 150.0 0.4 120.3 0.0 29.7 0.1 85.6 15.5 0.0 103.0 0.3 250.0 248.2 15.1 35.4 3.7 7.3 0.0 295.3 0.0 1.7 0.3 21.9 0.0 14.5 0.0 151.6 0.6 343.9 25.1 0.2 32.7 21.4 0.0 2.2 16.0 0.2 3.8 34.9 99.6 4.3 156.0 63.1 0.5 0.0 0.0 80.8 0.5 29.7 0.0 0.0 0.0 4.5 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.1 0.7 0.0 6.6 0.0 0.0 0.0 0.8 22.2 24.9 20.8 28.9 21.5 23.5 24.8 25.5 25.2 25.3 26.4 30.5 365.2 6.4 22.4 2.9 0.5 121.2 32.5 10.4 53.5 0.6 13.9 54.9 179.5 12.8 9.6 57.0 0.0 71.1 13.1 0.2 1.9 47.4 1.4 86.5 235.3 275.9 0.0 0.4 3.2 22.3 240.8 243.9 11.7 148.2 2.5 0.3 157.8 2.2 16.5 0.0 3.3 0.2 2.0 5.0 38.5 4.4 109.0 5.8 53.4 7.5 0.6 52.2 20.6 2.0 19.9 20.6 0.0 41.8 3.6 26.3 0.0 6.3 3.3 3.3 210.4 91.0 452.4 0.4 1.0 22.8 41.6 54.9 10.1 8.8 0.0 16.8 ADAMTS10 ADAM-TS10 ENSG00000142303 "ADAM metallopeptidase with thrombospondin type 1 motif 10" Q9H324 19 8580240-8610735 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 18.3;Excitatory neurons: 21.4;Inhibitory neurons: 19.9;Microglial cells: 30.9;Skeletal myocytes: 15.9;Smooth muscle cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 7.2;hTERT-RPE1: 7.5;NB-4: 37.0;REH: 9.8" "Region enriched" "Detected in many" 5 "cerebellum: 8.8" "Low region specificity" "Detected in all" HPA040223 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA040223: AB_10795376" "unprognostic (2.60e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (1.14e-1)" "unprognostic (8.16e-2)" "unprognostic (1.91e-4)" "unprognostic (4.98e-3)" "unprognostic (4.06e-2)" "unprognostic (2.24e-2)" "unprognostic (6.52e-2)" "unprognostic (2.47e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (6.86e-3)" "unprognostic (1.71e-1)" "unprognostic (2.33e-1)" "unprognostic (4.12e-2)" 15.9 8.2 7.1 2.3 7.3 1.8 9.5 5.0 11.9 13.0 5.8 7.3 0.8 12.7 0.7 4.1 10.2 1.9 8.5 7.6 8.7 6.9 6.3 8.2 3.2 7.1 6.8 8.3 7.8 0.8 4.1 1.7 6.7 8.4 0.5 0.4 4.1 1.5 2.8 8.8 6.3 1.5 6.0 5.4 3.8 2.4 8.1 1.4 6.2 0.8 1.3 5.7 8.7 6.5 0.0 4.6 2.5 0.0 0.4 0.3 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.2 1.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.0 7.2 0.0 0.3 0.0 0.1 1.8 0.0 0.0 0.0 7.5 0.1 0.3 0.1 0.0 0.0 0.0 0.3 37.0 1.5 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 1.2 0.1 0.4 2.0 3.1 4.4 2.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 7.3 5.0 11.9 7.6 8.7 7.1 6.8 6.7 6.0 8.1 6.5 5.6 0.0 0.0 18.3 0.3 1.7 0.6 0.1 0.0 1.5 1.2 1.5 1.3 5.7 0.1 0.0 0.0 0.1 6.9 0.0 0.0 8.8 5.1 0.4 7.4 5.8 0.0 1.3 21.4 0.5 0.0 6.4 1.1 0.4 0.0 1.8 6.8 2.0 0.9 0.0 19.9 0.3 0.0 2.7 6.0 2.4 7.5 3.3 0.0 30.9 0.6 0.8 11.3 9.5 1.2 0.9 0.0 6.0 1.3 0.2 0.0 0.1 0.0 0.2 6.6 15.9 15.0 0.1 0.4 0.1 0.9 0.4 3.2 0.6 0.1 0.3 ADAMTS12 ENSG00000151388 "ADAM metallopeptidase with thrombospondin type 1 motif 12" P58397 5 33523535-33892019 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 25.2;Fibroblasts: 22.9;Leydig cells: 22.1;Microglial cells: 73.1;Sertoli cells: 52.6;Theca cells: 55.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.4;hTERT-RPE1: 88.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035973, HPA075079" Uncertain Approved Nucleoli,Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" Nucleoli Mitochondria "HPA035973: AB_10669663, HPA075079: AB_2732278" "unprognostic (6.18e-3)" "unprognostic (3.12e-4)" "unprognostic (1.05e-1)" "unprognostic (8.37e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-1)" "unprognostic (2.60e-2)" "unprognostic (3.49e-3)" "unprognostic (3.78e-3)" "unprognostic (3.39e-2)" "unprognostic (5.63e-3)" "unprognostic (1.45e-1)" "unprognostic (4.27e-7)" "unprognostic (4.45e-3)" "unprognostic (1.47e-1)" "unprognostic (5.85e-2)" "prognostic unfavorable (6.78e-4)" 9.0 5.2 0.9 1.6 0.7 0.0 7.8 0.5 0.4 2.7 1.7 2.5 0.5 3.8 0.5 0.9 3.2 4.0 1.6 0.2 0.4 1.3 1.4 5.6 0.9 1.2 0.9 2.7 0.6 0.5 0.6 3.9 1.0 1.3 1.0 0.7 0.9 1.4 0.8 1.5 1.1 6.5 1.5 0.5 1.2 2.0 1.3 0.3 1.9 0.7 0.6 2.2 2.0 3.3 28.7 0.9 25.5 0.0 35.9 17.2 0.0 13.3 33.1 16.8 19.5 0.0 0.0 0.0 0.0 9.0 29.1 0.8 0.7 16.7 24.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 13.8 0.0 47.4 12.2 88.0 0.0 0.0 0.0 0.1 26.6 0.0 0.0 0.0 5.0 0.0 0.0 0.0 29.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 36.9 0.0 0.0 0.0 28.0 36.2 0.3 7.9 4.4 3.5 0.0 23.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.5 0.4 0.2 0.4 1.2 0.9 1.0 1.5 1.3 3.3 6.4 0.0 0.0 1.3 0.5 0.8 0.0 0.0 0.0 0.1 1.5 2.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.9 1.2 25.2 2.1 0.0 0.0 3.0 0.2 0.4 22.9 0.0 0.6 0.0 3.3 11.4 0.2 0.6 0.0 6.2 0.0 0.0 0.3 2.1 3.0 22.1 0.2 7.2 73.1 0.0 5.3 0.0 0.5 7.8 0.1 0.0 17.7 0.0 0.1 0.0 2.4 0.7 0.2 52.6 1.7 19.1 0.4 4.7 0.1 0.9 0.8 0.3 55.4 0.0 0.1 ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 63.8" "Cell type enhanced" "Detected in many" "Astrocytes: 16.0;Early spermatids: 19.3;Excitatory neurons: 12.4;Inhibitory neurons: 12.4;Late spermatids: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042014, HPA042844, HPA052077" Approved Approved Vesicles "Secreted to blood" NA NA 1300000000 120000000 "Cluster 34: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA042014: AB_2677798, HPA042844: AB_2678200, HPA052077: " "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (8.75e-4)" "unprognostic (1.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.02e-1)" "unprognostic (4.76e-2)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (4.52e-5)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.78e-2)" "unprognostic (3.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.30e-3)" 2.5 2.8 6.9 0.5 7.3 0.6 2.8 7.6 10.0 5.0 5.3 4.3 3.2 4.2 2.9 2.4 5.7 1.2 6.0 7.1 6.2 9.6 63.8 2.8 0.9 7.0 6.7 6.7 6.2 1.5 12.5 0.8 7.1 6.4 0.9 1.1 2.5 1.4 4.3 2.6 4.4 0.6 6.3 2.6 9.8 13.5 7.2 0.8 6.1 1.4 0.5 4.4 3.1 7.1 0.0 0.8 1.9 2.6 1.5 1.3 0.8 0.7 0.5 0.2 0.3 0.3 2.1 0.2 0.9 0.4 0.6 0.3 0.1 0.4 0.1 1.2 1.7 0.2 0.9 0.4 1.1 0.0 0.7 3.6 0.9 0.2 0.7 1.2 0.1 1.3 0.0 0.8 0.3 3.3 0.0 0.9 2.0 1.1 1.1 0.2 0.2 0.9 0.8 0.8 1.3 4.0 1.4 0.6 1.2 3.9 3.7 0.4 0.5 1.5 0.8 0.9 0.0 1.7 0.3 0.3 1.1 0.2 1.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 7.3 7.6 10.0 7.1 6.2 7.0 6.7 7.1 6.3 7.2 7.1 0.9 0.0 2.0 16.0 1.2 0.3 0.3 0.9 0.0 1.7 1.4 1.9 4.2 4.3 2.4 0.0 0.0 0.2 0.2 1.0 1.9 0.6 19.3 3.6 1.6 0.9 1.2 0.0 12.4 0.4 0.3 1.5 4.6 3.3 0.0 3.0 5.0 1.6 0.2 3.3 12.4 1.3 0.0 0.6 0.0 13.6 0.9 0.3 0.0 7.5 0.0 1.7 0.0 2.0 5.5 0.3 3.0 1.5 0.4 0.4 1.5 0.9 0.7 1.8 0.0 0.4 0.7 6.0 3.9 0.3 0.4 0.1 0.5 1.7 0.9 0.3 ADAMTS14 ENSG00000138316 "ADAM metallopeptidase with thrombospondin type 1 motif 14" Q8WXS8 10 70672506-70762441 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.9;gallbladder: 6.7;placenta: 7.6" "Group enriched" "Detected in some" 5 "Oligodendrocytes: 44.8;Paneth cells: 14.6;Theca cells: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.1;K-562: 10.4;RH-30: 5.4;U-138 MG: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "unprognostic (1.30e-1)" "unprognostic (1.04e-2)" "unprognostic (5.98e-3)" "unprognostic (3.54e-3)" "unprognostic (2.17e-3)" "unprognostic (2.40e-1)" "unprognostic (5.33e-3)" "unprognostic (2.35e-1)" "unprognostic (1.06e-1)" "unprognostic (3.28e-2)" "unprognostic (3.98e-2)" "unprognostic (6.81e-2)" "unprognostic (3.84e-13)" "unprognostic (3.90e-2)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" "unprognostic (2.16e-2)" 0.8 0.2 2.6 3.2 5.9 0.6 0.3 2.0 5.4 1.0 0.4 2.7 2.3 0.7 0.4 1.0 0.5 6.7 0.7 2.9 3.7 0.5 0.3 1.7 1.1 3.2 4.3 0.2 0.2 0.0 0.1 7.6 3.2 0.6 1.8 0.0 0.8 0.1 0.1 1.3 3.2 2.2 1.4 0.4 1.4 0.5 10.9 0.4 0.2 0.3 0.7 2.5 0.4 9.9 0.0 0.0 0.1 0.3 0.2 4.0 0.0 1.0 3.2 0.3 1.7 0.0 9.1 0.0 0.7 1.7 0.4 0.7 0.0 0.0 0.1 3.6 0.0 0.3 0.0 0.2 0.0 0.0 2.4 0.3 0.1 0.8 0.2 1.0 0.0 0.0 10.4 0.0 1.3 0.0 0.0 0.9 0.3 0.1 0.0 0.0 5.4 0.2 0.0 0.0 3.4 0.5 0.0 0.1 0.3 0.1 0.0 0.0 0.0 8.9 0.1 0.7 0.5 0.8 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 5.9 2.0 5.4 2.9 3.7 3.2 4.3 3.2 1.4 10.9 9.9 0.1 0.0 0.0 0.3 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.1 0.7 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.1 0.5 0.1 0.3 0.0 2.1 0.3 0.0 0.1 2.1 0.0 0.2 4.5 0.1 0.0 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.8 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 2.0 44.8 0.1 14.6 0.0 0.1 0.0 0.7 0.0 1.4 0.0 0.0 1.8 1.1 0.0 0.0 0.2 0.1 0.4 0.0 17.9 0.5 0.1 ADAMTS15 ENSG00000166106 "ADAM metallopeptidase with thrombospondin type 1 motif 15" Q8TE58 11 130448974-130476641 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 26.4" "Cell type enhanced" "Detected in some" "Adipocytes: 8.6;Cardiomyocytes: 11.0;Endometrial stromal cells: 15.6;Fibroblasts: 9.6;Gastric mucus-secreting cells: 8.2;Glandular and luminal cells: 7.5;Granulosa cells: 6.8;Skeletal myocytes: 6.9" "Cancer enhanced" "Detected in many" "breast cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 72.0;ASC TERT1: 43.0;EFO-21: 36.6;hTERT-RPE1: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA042867 Uncertain Approved Cytosol "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA042867: AB_10794535" "unprognostic (7.64e-2)" "unprognostic (1.49e-3)" "unprognostic (7.15e-2)" "unprognostic (1.34e-3)" "unprognostic (1.07e-3)" "unprognostic (7.07e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (9.72e-4)" "unprognostic (6.18e-2)" "unprognostic (4.37e-2)" "unprognostic (2.56e-1)" "unprognostic (7.40e-2)" "unprognostic (1.29e-2)" "unprognostic (5.95e-3)" "unprognostic (6.68e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.63e-5)" 26.4 1.2 0.4 1.7 0.5 0.0 15.3 0.4 0.8 3.4 1.7 3.2 0.5 4.3 1.3 3.7 9.8 2.3 14.5 0.4 0.9 11.0 0.4 7.2 1.1 4.4 0.6 2.7 1.4 0.4 1.3 16.9 1.5 1.9 1.9 0.2 1.3 1.1 1.8 5.0 3.6 4.6 1.0 2.3 5.5 0.9 1.2 1.1 7.0 1.0 0.3 8.8 2.6 1.0 0.0 2.6 1.6 0.8 72.0 43.0 0.0 2.7 5.2 1.0 0.2 0.5 1.2 0.0 36.6 0.2 2.6 7.0 0.6 0.7 0.2 0.0 1.7 0.0 3.3 0.0 0.7 0.0 0.0 14.1 0.0 0.6 0.1 19.5 0.0 0.3 0.0 0.0 0.0 0.1 0.1 8.1 1.3 0.0 5.7 0.0 4.1 0.0 0.1 0.1 0.6 0.0 12.1 0.0 0.0 5.2 3.9 0.0 0.0 0.6 8.5 7.0 3.5 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.8 0.4 0.9 4.4 0.6 1.5 1.0 1.2 1.0 8.6 0.0 0.0 0.3 0.2 0.5 0.1 3.5 0.0 1.3 5.6 2.7 11.0 0.0 0.5 1.8 0.0 0.6 0.0 1.0 0.0 0.0 0.0 4.4 15.6 1.7 0.0 0.0 0.4 0.8 0.6 9.6 8.2 7.5 0.0 6.8 0.4 0.1 0.9 0.0 1.6 0.5 2.0 0.0 0.3 0.0 5.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.9 0.7 0.0 0.0 0.1 1.0 0.5 0.0 0.0 6.9 3.6 0.2 0.3 0.0 0.3 0.8 0.1 0.0 1.8 0.1 ADAMTS16 ADAMTS16s ENSG00000145536 "ADAM metallopeptidase with thrombospondin type 1 motif 16" Q8TE57 5 5140330-5320304 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0;ovary: 10.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 7.3;Excitatory neurons: 44.7;Fibroblasts: 13.7;Granulosa cells: 22.2;Theca cells: 15.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.9;SuSa: 3.5;U-2197: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067668 Approved "Nucleoplasm,Nuclear membrane,Midbody ring,Mitochondria" "Secreted to extracellular matrix" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" "Nucleoplasm, Midbody ring" "HPA067668: " "unprognostic (8.48e-2)" "unprognostic (1.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.98e-4)" "unprognostic (1.91e-2)" "unprognostic (5.04e-2)" "unprognostic (7.64e-2)" "unprognostic (7.80e-3)" "unprognostic (2.12e-2)" "unprognostic (5.44e-2)" "unprognostic (1.51e-2)" "unprognostic (2.18e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.20e-4)" "unprognostic (1.46e-1)" "unprognostic (4.59e-3)" "unprognostic (2.86e-3)" 5.4 0.2 1.4 0.4 1.9 0.5 0.7 17.0 2.6 1.4 0.0 0.7 0.6 1.3 1.6 1.5 0.7 6.4 0.2 3.4 0.0 3.5 0.4 0.7 0.2 0.2 0.2 10.4 4.5 0.1 0.0 0.2 0.7 0.1 0.3 1.2 0.2 0.5 0.2 0.4 0.5 1.1 0.0 0.2 0.2 0.4 0.0 0.2 0.3 0.2 0.1 1.0 0.6 1.8 1.7 1.7 1.7 0.1 0.1 0.3 0.2 0.0 0.0 0.4 0.5 0.0 1.4 0.1 2.1 0.0 3.0 0.1 0.0 0.0 0.4 0.1 0.9 0.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 3.9 0.1 0.5 0.0 0.3 0.6 0.4 0.7 0.0 0.4 0.2 1.1 0.0 1.6 0.4 2.2 0.1 0.0 0.1 0.5 0.1 0.1 0.1 0.1 3.5 0.1 0.1 0.1 2.1 3.0 5.8 1.4 0.9 0.3 0.1 3.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 1.9 17.0 2.6 3.4 0.0 0.2 0.2 0.7 0.0 0.0 1.8 0.7 0.0 0.6 2.6 0.0 0.0 0.0 0.0 0.6 2.0 0.7 0.4 0.5 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 5.0 0.1 0.0 0.0 44.7 0.0 0.0 13.7 0.5 0.5 0.0 22.2 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.8 0.0 0.0 0.0 1.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 6.9 1.6 0.1 0.0 0.0 0.0 0.0 0.1 15.9 0.0 0.0 ADAMTS17 "FLJ16363, FLJ32769" ENSG00000140470 "ADAM metallopeptidase with thrombospondin type 1 motif 17" Q8TE56 15 99971437-100342005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Deafness, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.7" "Group enriched" "Detected in many" 8 "Astrocytes: 116.9;Early spermatids: 108.4;Inhibitory neurons: 275.7;Late spermatids: 91.0;Oligodendrocyte precursor cells: 337.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEK 293: 6.4;JURKAT: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062487 Approved Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA062487: AB_2684780" "unprognostic (7.73e-2)" "unprognostic (2.38e-2)" "unprognostic (1.79e-2)" "unprognostic (9.03e-3)" "unprognostic (2.56e-1)" "unprognostic (9.90e-3)" "unprognostic (5.78e-2)" "unprognostic (1.18e-3)" "unprognostic (5.03e-3)" "unprognostic (4.70e-2)" "unprognostic (2.93e-1)" "unprognostic (1.27e-1)" "unprognostic (3.35e-2)" "unprognostic (8.48e-2)" "unprognostic (1.21e-1)" "unprognostic (7.43e-3)" "unprognostic (6.43e-2)" 0.8 1.2 1.6 0.5 1.1 0.6 0.6 0.3 2.7 1.4 6.0 0.9 0.6 1.2 0.6 2.1 1.8 0.3 1.3 1.3 0.6 1.1 7.5 1.5 0.5 1.2 0.7 1.7 5.0 0.2 1.2 0.5 0.8 1.0 0.4 0.7 2.6 0.5 5.6 2.2 1.2 0.5 0.7 0.9 1.0 2.7 1.0 10.7 0.7 0.1 0.5 1.6 1.4 1.1 0.0 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 1.2 0.3 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.7 2.0 0.5 0.2 0.9 1.0 0.0 0.3 2.3 0.0 0.2 1.7 0.2 0.2 2.2 2.7 0.4 0.0 0.2 0.3 0.0 0.6 0.6 0.0 0.2 0.0 0.0 0.0 0.4 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.1 0.3 2.7 1.3 0.6 1.2 0.7 0.8 0.7 1.0 1.1 0.7 0.0 0.0 116.9 0.3 1.0 0.9 0.1 3.4 0.8 1.5 1.3 4.3 1.5 0.9 0.0 0.0 0.1 2.6 0.4 1.9 0.1 108.4 1.2 2.8 0.9 0.0 0.0 8.2 0.9 0.0 1.6 5.1 1.8 0.0 0.1 0.4 4.4 8.2 21.9 275.7 0.7 0.0 0.6 0.3 91.0 2.1 0.4 0.0 22.5 0.0 1.3 1.0 337.3 9.5 0.3 0.2 0.0 0.8 1.6 0.5 0.1 0.0 0.7 0.0 3.2 0.9 1.7 1.9 2.1 0.6 0.1 3.7 2.5 0.4 0.9 ADAMTS18 ADAMTS21 ENSG00000140873 "ADAM metallopeptidase with thrombospondin type 1 motif 18" Q8TE60 16 77247813-77435034 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.0;placenta: 20.6" "Cell type enhanced" "Detected in some" "Adipocytes: 36.8;Granulosa cells: 15.0;Muller glia cells: 13.7;Oligodendrocytes: 16.9;Rod photoreceptor cells: 7.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 11.6;HUVEC TERT2: 8.0;SuSa: 10.6;TIME: 2.5;U-87 MG: 4.8" "Region enriched" "Detected in single" 5 "cerebellum: 3.3" "Low region specificity" "Detected in all" HPA044326 Uncertain Approved "Midbody,Mitotic spindle" "Secreted to extracellular matrix" Yes NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Midbody, Mitotic spindle" "HPA044326: AB_10961006" "unprognostic (1.10e-2)" "unprognostic (2.78e-1)" "unprognostic (1.38e-1)" "unprognostic (2.50e-1)" "unprognostic (8.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.98e-1)" "unprognostic (4.11e-2)" "unprognostic (2.20e-2)" "unprognostic (8.17e-4)" "unprognostic (1.77e-5)" "unprognostic (2.17e-1)" "unprognostic (3.41e-1)" "unprognostic (2.47e-4)" 3.1 0.1 1.3 0.3 3.0 0.0 2.9 11.0 2.5 1.2 0.5 0.0 0.1 0.8 0.0 0.1 0.2 0.6 0.0 1.8 2.7 0.2 0.0 0.1 0.1 4.3 2.4 0.1 0.3 0.0 0.8 20.6 3.7 0.4 0.0 2.0 1.3 0.1 0.6 0.1 0.0 0.6 1.7 0.0 0.0 0.2 2.4 0.9 0.0 0.0 0.0 0.9 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.6 0.0 0.5 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.0 11.0 2.5 1.8 2.7 4.3 2.4 3.7 1.7 2.4 5.9 36.8 0.0 0.0 4.6 0.1 0.1 0.1 0.0 0.0 1.8 1.5 4.3 0.6 0.0 0.0 1.8 2.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.3 0.0 15.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.1 0.2 0.6 0.0 0.1 0.3 0.0 0.1 0.0 0.0 ADAMTS19 ENSG00000145808 "ADAM metallopeptidase with thrombospondin type 1 motif 19" 5 129460281-129738683 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "brain: 3.3;cervix: 10.2;endometrium 1: 9.8;placenta: 3.7;smooth muscle: 5.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 82.6;Inhibitory neurons: 79.7;Oligodendrocytes: 31.8" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.7;testis cancer: 1.2" "Region enhanced" "Detected in some" "basal ganglia: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "MCF7: 15.9;SH-SY5Y: 34.8" "Region enriched" "Detected in single" 5 "olfactory bulb: 2.6" "Low region specificity" "Detected in many" "HPA056171, HPA058438" Uncertain Approved Vesicles,Midbody "Secreted to extracellular matrix" Yes NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Midbody" "HPA056171: AB_2683054, HPA058438: AB_2683718" "unprognostic (1.14e-1)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-3)" "unprognostic (1.09e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-2)" "unprognostic (4.17e-2)" "unprognostic (5.99e-3)" "unprognostic (5.17e-1)" "unprognostic (1.14e-1)" "unprognostic (5.88e-2)" "unprognostic (3.06e-2)" 0.0 0.6 1.0 0.0 3.3 0.0 0.0 0.0 1.5 10.2 0.1 0.2 0.1 9.8 0.0 0.2 0.2 0.0 0.2 0.8 0.2 0.3 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.1 0.0 3.7 0.0 0.1 0.3 0.5 0.3 0.0 0.5 0.0 0.1 5.9 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.3 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 15.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 34.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.3 0.0 1.5 0.8 0.2 0.0 0.5 0.0 0.0 0.3 0.6 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 1.4 0.0 0.0 1.8 0.0 15.6 0.0 0.3 0.0 0.0 1.5 0.5 8.9 0.2 0.0 0.0 82.6 0.2 0.7 1.0 0.0 0.7 0.0 0.0 0.0 0.0 1.7 0.0 79.7 0.1 0.0 0.0 0.3 0.7 0.0 0.1 0.0 1.0 0.0 1.1 0.0 12.5 31.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.4 0.1 0.1 0.0 5.2 0.1 0.1 0.3 0.0 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 32.2;Excitatory neurons: 17.9;Fibroblasts: 30.7;Hepatic stellate cells: 17.2;Kupffer cells: 71.4;Sertoli cells: 26.3;Smooth muscle cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 35.8;BJ: 31.4;fHDF/TERT166: 39.3;HHSteC: 115.5;HSkMC: 94.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 36.9 10.9 0.8 2.4 4.2 0.3 22.7 0.9 3.5 20.6 0.9 10.5 1.4 21.7 0.5 5.5 15.5 6.1 22.3 0.5 0.9 7.5 15.8 29.6 1.8 4.5 3.3 12.1 5.8 0.4 15.1 9.7 4.2 9.0 1.4 0.2 5.3 1.8 2.9 9.4 11.6 9.1 0.2 38.4 9.3 3.9 2.5 0.4 6.8 0.8 0.6 15.0 16.7 2.2 0.0 0.0 0.1 0.7 36.0 35.8 0.0 31.4 5.4 11.5 12.4 0.1 0.0 0.0 0.2 39.3 0.7 0.1 1.8 0.0 5.1 0.0 1.5 0.0 0.1 2.3 115.5 0.0 0.0 94.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.9 1.2 0.1 0.0 0.4 1.9 0.0 10.7 0.0 19.1 3.0 24.5 0.0 0.3 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.8 4.2 0.9 3.5 0.5 0.9 4.5 3.3 4.2 0.2 2.5 2.2 3.3 0.0 1.1 1.6 0.1 2.2 0.4 0.0 2.2 0.3 0.2 5.2 1.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.3 0.9 32.2 1.4 0.0 0.0 17.9 0.0 0.3 30.7 0.0 0.8 1.3 6.5 17.2 0.5 5.1 0.0 8.5 0.0 0.0 71.4 4.4 3.4 5.0 10.4 0.0 4.7 0.3 0.1 0.0 3.0 2.4 0.5 0.0 12.8 0.1 0.4 0.0 0.2 0.0 0.0 26.3 4.7 20.4 2.1 4.8 0.2 2.7 0.0 0.4 0.6 0.0 0.1 ADAMTS20 GON-1 ENSG00000173157 "ADAM metallopeptidase with thrombospondin type 1 motif 20" P59510 12 43353866-43552203 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 3.1" "Group enriched" "Detected in some" 4 "Bipolar cells: 5.1;Inhibitory neurons: 16.1;Oligodendrocyte precursor cells: 11.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "medulla oblongata: 2.8;pons: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 3.6;NB-4: 1.6;NTERA-2: 2.8;SuSa: 2.2;U-266/70: 4.0;U-266/84: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027608, HPA027609" Uncertain "Secreted to extracellular matrix" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA027608: AB_10600098, HPA027609: AB_10599024" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (1.91e-2)" "unprognostic (2.04e-1)" "unprognostic (9.61e-2)" "unprognostic (3.29e-1)" "unprognostic (6.67e-2)" "unprognostic (2.26e-1)" "unprognostic (1.05e-4)" "unprognostic (7.42e-2)" "unprognostic (2.02e-1)" "unprognostic (9.81e-3)" "unprognostic (2.57e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.5 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.1 0.0 0.0 1.6 2.8 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.2 0.7 0.0 0.0 0.0 0.3 0.0 0.0 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 2.8 0.1 3.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ADAMTS3 "ADAMTS-4, KIAA0366" ENSG00000156140 "ADAM metallopeptidase with thrombospondin type 1 motif 3" O15072 4 72280969-72569221 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Excitatory neurons: 50.2;Leydig cells: 19.9;Rod photoreceptor cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;AN3-CA: 7.8;HEL: 14.1;K-562: 12.3;SH-SY5Y: 7.0;U-2 OS: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021368, HPA021369" Uncertain Approved "Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Intermediate filaments" "HPA021368: AB_2670681, HPA021369: AB_2670682" "unprognostic (1.93e-1)" "unprognostic (3.47e-3)" "unprognostic (1.41e-1)" "unprognostic (1.05e-3)" "unprognostic (6.11e-2)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (1.60e-3)" "unprognostic (5.92e-4)" "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (2.60e-1)" "unprognostic (8.63e-3)" "unprognostic (1.65e-3)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" "unprognostic (1.50e-4)" 2.3 0.8 0.5 1.0 2.5 0.8 3.2 0.0 1.5 0.4 0.1 0.3 0.1 1.9 1.7 0.2 2.9 0.6 0.9 1.5 0.6 0.9 0.2 1.1 0.8 0.0 0.2 2.0 0.3 2.7 0.2 0.7 0.1 0.7 0.3 8.4 0.4 1.1 0.2 0.4 0.2 1.7 0.0 0.7 0.5 1.9 0.1 0.6 1.2 0.3 0.3 1.3 0.4 0.4 0.0 0.0 13.2 7.8 0.1 0.3 0.1 0.7 2.1 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.8 0.0 1.8 0.0 1.8 14.1 0.9 0.0 0.2 0.0 0.0 1.7 0.1 0.6 0.1 3.3 0.0 0.0 12.3 0.0 0.0 0.0 1.3 0.0 2.2 0.0 4.0 0.0 2.6 0.0 4.6 0.0 0.5 7.0 0.0 0.6 0.2 1.4 0.1 0.2 0.1 5.6 8.5 0.0 0.7 0.0 0.0 0.0 1.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.0 1.5 1.5 0.6 0.0 0.2 0.1 0.0 0.1 0.4 1.8 0.0 3.4 7.5 0.0 0.5 0.9 0.0 0.0 0.9 0.8 3.2 1.2 1.5 1.3 1.8 14.6 0.0 0.0 0.0 0.0 0.0 4.1 2.2 5.1 3.7 0.0 2.5 50.2 0.0 0.3 3.3 0.0 0.7 1.3 1.9 3.9 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.7 1.9 19.9 0.3 0.0 1.0 0.0 1.8 0.0 7.1 1.3 0.0 0.0 4.5 0.0 1.1 0.0 0.3 0.5 12.9 0.0 0.3 1.2 1.2 0.8 0.3 0.0 0.0 0.0 2.8 0.0 0.1 ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184302-161199054 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.8;ovary: 95.9" "Cell type enhanced" "Detected in many" "Adipocytes: 80.3;Endothelial cells: 115.5;Fibroblasts: 88.8;Oligodendrocytes: 56.0;Sertoli cells: 52.6;Smooth muscle cells: 313.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 4.4" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 11.8;HUVEC TERT2: 14.4;SH-SY5Y: 7.9;TIME: 12.2;U-138 MG: 7.4;U-251 MG: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "CAB025876: , HPA051296: AB_2681426, HPA068374: AB_2685978" "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" 116.8 9.8 6.1 16.3 31.5 0.7 43.4 31.1 19.2 16.4 5.8 18.2 0.8 15.0 0.2 6.2 34.6 14.3 53.6 8.1 15.2 26.0 8.7 50.3 1.6 38.2 29.6 95.9 9.0 2.1 13.0 3.2 31.6 16.9 2.0 1.5 5.2 0.5 13.3 5.0 9.4 10.5 28.3 1.8 22.8 1.8 26.2 1.1 21.3 0.4 0.3 31.8 12.2 48.0 0.0 0.0 0.2 0.1 6.4 4.0 0.6 5.4 0.2 0.5 3.0 0.2 0.2 0.2 4.4 1.7 0.0 0.1 0.0 0.0 1.9 0.1 0.3 0.2 0.5 1.3 0.6 0.0 0.1 4.5 0.0 11.8 0.1 0.0 14.4 0.1 0.2 0.3 0.4 0.1 0.0 0.2 5.3 0.0 0.0 0.1 5.1 0.1 0.0 0.1 0.1 7.9 0.0 0.1 0.1 0.3 0.2 0.5 12.2 7.4 0.1 0.4 10.8 0.2 0.1 0.1 2.2 0.1 0.1 0.5 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.0 4.4 0.2 0.1 6.1 31.5 31.1 19.2 8.1 15.2 38.2 29.6 31.6 28.3 26.2 48.0 80.3 0.0 4.1 0.0 0.2 31.2 3.2 0.0 2.2 2.2 8.6 5.5 5.5 0.0 0.6 0.0 0.0 0.3 0.5 0.2 0.0 0.3 0.0 0.3 13.0 115.5 0.0 0.0 0.4 0.0 0.3 88.8 0.5 0.5 0.0 0.3 43.2 0.9 1.0 3.3 0.1 0.0 0.0 1.0 32.6 0.2 0.3 3.2 35.6 2.8 1.0 0.5 0.0 0.0 56.0 0.0 0.0 1.2 0.7 9.8 0.0 0.1 0.0 1.0 52.6 21.2 313.7 2.7 0.6 2.7 19.0 0.4 3.7 1.6 0.3 7.7 ADAMTS5 "ADAMTS11, ADMP-2" ENSG00000154736 "ADAM metallopeptidase with thrombospondin type 1 motif 5" Q9UNA0 21 26917922-26967088 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 26.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 38.2;Endometrial stromal cells: 72.1;Fibroblasts: 88.6;Leydig cells: 62.7;Skeletal myocytes: 110.2;Smooth muscle cells: 44.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 31.6;ASC TERT1: 13.9;fHDF/TERT166: 11.9;RH-30: 33.1;U-87 MG: 13.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA005661, CAB025996, HPA030906, HPA030908" Approved Supported Nucleoplasm "Secreted to extracellular matrix" NA NA 28000 "Cluster 5: Breast - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB025996: , HPA005661: AB_1078101, HPA030906: AB_2673654, HPA030908: AB_2673655" "unprognostic (1.97e-1)" "unprognostic (2.88e-3)" "unprognostic (2.69e-2)" "unprognostic (4.01e-2)" "unprognostic (4.67e-1)" "unprognostic (2.10e-2)" "unprognostic (4.38e-8)" "unprognostic (1.11e-3)" "unprognostic (7.66e-2)" "unprognostic (6.17e-2)" "unprognostic (8.13e-2)" "unprognostic (7.76e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (6.69e-3)" "unprognostic (3.01e-1)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.15e-1)" 17.5 0.8 0.3 1.0 0.6 0.0 10.8 3.3 0.3 8.8 2.6 2.7 0.8 12.5 2.4 1.6 4.2 1.6 3.3 0.5 0.9 2.5 1.4 1.0 0.6 1.4 0.9 16.6 0.4 1.5 0.4 26.2 0.9 3.0 1.3 0.6 2.0 1.8 2.0 4.2 3.4 7.5 1.5 7.7 2.2 0.8 0.4 0.3 6.8 3.7 0.1 4.2 3.6 1.2 0.0 0.0 0.0 0.0 31.6 13.9 0.0 1.7 0.2 1.4 0.6 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 2.3 0.0 1.3 0.0 0.3 0.0 3.5 0.1 0.0 8.0 0.0 1.1 0.2 0.2 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 33.1 0.0 3.4 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 8.3 0.4 1.9 0.9 0.0 0.0 0.0 13.0 0.1 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 3.3 0.3 0.5 0.9 1.4 0.9 0.9 1.5 0.4 1.2 24.3 0.0 0.5 0.3 0.1 2.9 0.2 0.4 0.0 9.8 1.5 38.2 2.7 0.0 0.6 3.7 0.0 1.1 0.3 0.0 0.0 0.0 6.4 2.0 72.1 10.6 1.8 0.0 0.5 0.2 1.6 88.6 0.0 1.3 0.0 3.0 3.3 0.0 1.9 0.0 11.6 0.0 0.0 0.0 4.6 1.0 62.7 1.4 3.6 3.7 4.0 0.1 0.0 12.5 0.2 0.0 0.0 9.1 0.0 0.3 0.0 2.2 0.0 0.2 13.1 110.2 44.9 0.3 0.9 0.4 3.0 2.7 0.8 20.0 0.0 0.1 ADAMTS6 ADAM-TS6 ENSG00000049192 "ADAM metallopeptidase with thrombospondin type 1 motif 6" Q9UKP5 5 65148738-65481920 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.6;Inhibitory neurons: 63.6;Microglial cells: 31.9;Oligodendrocyte precursor cells: 139.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.1;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Cell line enhanced" "Detected in many" "BJ: 12.6;HBF TERT88: 13.4;hTEC/SVTERT24-B: 12.6;hTERT-HME1: 14.9;TIME: 14.5;U-2197: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043441 Enhanced "Secreted to extracellular matrix" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043441: AB_2678484" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (2.70e-3)" "unprognostic (4.33e-2)" "unprognostic (1.03e-2)" "unprognostic (2.39e-2)" "unprognostic (8.24e-2)" "unprognostic (1.65e-2)" "unprognostic (4.77e-2)" "unprognostic (8.04e-2)" "unprognostic (1.56e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-6)" "unprognostic (3.23e-5)" "unprognostic (2.09e-1)" "unprognostic (3.02e-4)" "unprognostic (4.18e-3)" 0.5 0.1 0.2 0.6 0.2 0.0 0.3 0.2 0.3 0.3 0.5 0.3 0.1 1.1 0.7 0.2 0.6 1.4 0.3 0.2 0.6 0.2 0.0 0.5 0.4 0.3 0.4 0.3 0.0 0.0 0.1 1.9 0.3 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.6 0.6 0.3 0.7 0.3 0.5 0.3 0.2 0.1 0.1 0.3 0.7 0.3 0.2 2.7 0.0 0.6 0.6 0.0 2.0 0.0 12.6 7.4 7.7 9.0 0.0 0.3 0.0 0.1 4.8 5.3 0.5 0.1 2.4 13.4 2.0 0.0 0.2 5.1 0.3 0.4 0.0 0.7 0.9 0.0 12.6 14.9 3.7 6.9 1.3 0.0 0.0 4.8 0.0 0.7 0.0 0.1 0.3 0.1 0.4 2.6 0.0 0.0 0.0 0.3 0.5 0.2 0.0 0.0 1.6 0.0 0.1 14.5 3.0 4.5 16.2 10.2 0.1 0.0 0.0 3.4 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.4 2.1 0.1 0.2 0.0 1.3 0.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.6 0.3 0.4 0.3 0.3 0.3 0.2 11.3 0.0 0.0 4.9 16.1 0.3 0.0 0.6 0.6 13.9 0.3 0.5 1.8 1.5 0.1 3.7 0.0 34.6 3.2 0.2 0.0 1.4 15.2 8.5 7.4 13.3 0.0 0.0 16.7 0.0 4.7 5.5 0.0 25.7 1.3 18.7 8.9 0.3 2.4 0.0 63.6 0.5 2.0 0.3 1.0 8.0 12.2 3.2 0.0 31.9 0.3 17.4 1.0 139.7 2.1 2.6 0.0 18.0 2.5 0.1 0.1 1.0 0.1 1.1 6.6 5.1 10.5 6.1 8.9 0.3 0.0 14.2 5.1 2.2 0.6 0.0 ADAMTS7 "ADAM-TS7, DKFZp434H204" ENSG00000136378 "ADAM metallopeptidase with thrombospondin type 1 motif 7" Q9UKP4 15 78759206-78811464 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 30.6" "Cell type enriched" "Detected in some" 4 "Theca cells: 44.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "HMC-1: 259.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA045284, HPA048453" Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA045284: AB_2679285, HPA048453: AB_2680399" "unprognostic (5.94e-3)" "unprognostic (9.94e-3)" "unprognostic (2.76e-2)" "unprognostic (7.09e-2)" "unprognostic (3.38e-1)" "unprognostic (1.93e-1)" "unprognostic (5.88e-4)" "unprognostic (3.34e-3)" "unprognostic (2.89e-2)" "unprognostic (3.31e-2)" "unprognostic (1.83e-2)" "unprognostic (3.79e-1)" "unprognostic (1.34e-2)" "prognostic unfavorable (9.53e-4)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (8.86e-2)" 6.6 5.3 0.5 1.8 0.4 0.1 3.8 0.3 0.5 6.0 0.6 4.2 1.1 7.2 0.1 0.9 2.2 2.3 30.6 0.4 0.5 2.2 1.1 6.3 0.9 0.5 0.5 6.1 0.5 0.4 0.8 2.1 0.4 1.8 0.2 0.5 1.3 0.4 1.1 1.8 2.6 1.4 0.2 5.2 2.2 4.1 0.7 0.1 2.1 0.5 0.2 3.0 2.5 0.6 0.0 1.1 16.5 7.5 6.9 8.2 20.9 3.7 1.3 1.0 0.6 0.0 0.1 0.0 4.8 0.4 1.0 0.4 0.4 2.0 0.0 0.3 0.6 2.1 0.5 0.1 6.9 0.0 259.9 3.3 2.0 1.9 1.0 5.3 24.0 0.0 0.3 0.7 5.6 0.0 0.1 4.9 4.7 0.0 1.4 17.3 7.7 0.3 0.5 0.9 0.3 23.9 4.8 0.0 0.6 4.0 3.2 0.4 29.8 9.4 1.0 3.3 0.0 0.1 0.0 0.0 1.6 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.5 0.4 0.5 0.5 0.5 0.4 0.2 0.7 0.6 7.5 0.0 0.0 3.6 0.3 0.4 0.2 0.7 0.0 0.3 0.1 0.5 9.8 0.0 0.3 0.0 0.0 0.3 0.2 0.1 0.0 0.1 4.9 0.8 7.5 10.5 0.0 0.0 0.1 0.0 0.3 10.1 0.5 0.9 3.8 7.2 2.9 0.3 0.7 0.0 0.2 0.0 2.0 0.0 0.8 2.7 1.5 0.1 1.8 1.0 0.1 1.3 0.0 9.5 1.4 0.3 0.0 1.9 0.0 0.3 0.0 0.1 0.3 0.1 0.0 3.7 5.0 2.6 2.0 0.2 0.1 0.3 0.5 44.9 0.1 0.3 ADAMTS8 "ADAM-TS8, FLJ41712, METH2" ENSG00000134917 "ADAM metallopeptidase with thrombospondin type 1 motif 8" Q9UP79 11 130404923-130428609 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.6" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 14.5;Endometrial stromal cells: 30.9;Glandular and luminal cells: 37.7;Skeletal myocytes: 26.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.5;HeLa: 1.3;HMC-1: 4.4;NTERA-2: 2.2;U-2 OS: 9.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066349 Approved "Secreted to extracellular matrix" NA NA 3600000 "Cluster 19: Lung - Lung function" "Cluster 9: U-2 OS - Unknown function" "Cluster 44: Endometrium - Transcription" "HPA066349: AB_2685662" "unprognostic (4.76e-6)" "unprognostic (3.92e-2)" "unprognostic (6.13e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.41e-1)" "unprognostic (7.81e-2)" "unprognostic (3.09e-2)" "unprognostic (9.83e-2)" "unprognostic (1.09e-4)" "unprognostic (3.05e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (4.66e-3)" "unprognostic (4.03e-3)" "unprognostic (5.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.41e-1)" 1.8 0.1 1.5 10.1 2.7 0.0 0.7 0.0 3.7 2.0 0.0 7.0 1.1 3.0 1.0 3.0 2.1 1.6 2.3 3.5 0.0 0.5 0.0 27.6 0.1 0.7 0.1 0.4 0.7 0.0 0.2 2.6 0.2 2.7 0.5 0.0 0.5 4.9 0.5 0.3 2.1 4.2 0.1 0.4 5.3 0.3 1.0 0.0 0.2 0.5 0.0 4.2 0.9 1.8 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 1.3 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.7 0.0 3.7 3.5 0.0 0.7 0.1 0.2 0.1 1.0 1.8 1.3 0.0 0.6 1.0 0.0 0.4 0.4 0.1 0.0 2.4 2.3 3.9 9.1 0.0 1.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 14.5 30.9 0.6 0.0 0.0 7.4 0.0 0.0 6.6 0.0 37.7 1.3 1.3 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.7 0.5 0.0 0.1 1.8 2.8 0.0 0.1 1.0 0.5 5.9 0.0 0.0 1.5 0.0 0.5 0.0 0.1 2.6 0.2 0.0 26.9 5.7 0.1 0.3 0.1 0.1 0.0 0.6 0.1 0.0 0.0 ADAMTS9 KIAA1312 ENSG00000163638 "ADAM metallopeptidase with thrombospondin type 1 motif 9" Q9P2N4 3 64515654-64688000 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 41.2" "Cell type enhanced" "Detected in many" "Adipocytes: 166.3;Astrocytes: 84.2;Basal prostatic cells: 87.2;Endometrial stromal cells: 179.1;Endothelial cells: 221.0;Prostatic glandular cells: 115.7;Smooth muscle cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 23.6;RPTEC TERT1: 27.1;SH-SY5Y: 128.3;SuSa: 40.5;WM-115: 28.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028567, HPA028577, HPA028601" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" No NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Endoplasmic reticulum" "HPA028567: AB_10599275, HPA028577: AB_10600330, HPA028601: AB_2672694" "unprognostic (2.21e-1)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (4.83e-2)" "unprognostic (3.08e-1)" "unprognostic (1.37e-2)" "unprognostic (7.80e-3)" "unprognostic (5.85e-2)" "unprognostic (2.77e-1)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (7.67e-2)" "unprognostic (3.16e-3)" "unprognostic (1.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-3)" "unprognostic (5.00e-3)" 41.2 4.8 4.0 12.2 5.0 0.1 19.0 5.5 5.3 16.2 7.9 8.1 1.2 13.2 1.1 5.3 10.2 7.8 15.6 4.4 5.6 9.5 2.7 13.6 1.9 10.8 8.1 7.3 9.8 6.3 2.2 31.7 8.5 7.9 2.7 1.4 3.2 3.7 7.4 2.6 3.7 12.1 8.0 4.1 4.7 0.8 8.1 1.0 7.3 7.3 1.1 22.5 9.0 6.4 0.0 1.2 13.9 0.0 0.6 0.1 1.3 0.2 0.0 0.0 0.0 1.9 0.0 0.0 2.3 0.3 0.4 0.0 1.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.9 0.0 8.8 2.6 0.0 0.0 0.5 0.0 23.6 0.0 0.5 0.0 0.3 0.1 0.0 0.0 7.5 1.1 0.0 0.0 2.4 0.1 27.1 0.3 0.1 128.3 0.0 0.0 0.0 40.5 0.0 0.7 5.4 0.8 0.4 0.0 0.8 0.0 0.0 0.0 0.5 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.0 5.5 5.3 4.4 5.6 10.8 8.1 8.5 8.0 8.1 6.4 166.3 3.2 4.8 84.2 0.0 17.5 87.2 0.0 4.6 0.0 6.9 15.9 6.6 2.8 2.6 38.6 2.1 1.0 0.2 1.1 0.0 69.7 0.9 13.2 179.1 221.0 1.2 0.0 4.2 3.3 0.6 31.4 1.5 33.8 0.0 8.4 27.1 0.3 7.5 0.0 14.3 1.1 0.0 0.3 20.1 0.4 2.5 2.7 26.6 21.5 0.0 0.2 0.0 26.7 0.6 45.5 1.0 2.2 0.0 115.7 0.0 10.8 0.1 0.1 0.0 20.7 94.8 0.3 0.7 1.3 13.5 1.6 3.2 12.1 0.9 36.7 ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 13.3" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 2.6" "Region enhanced" "Detected in many" "thalamus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 118.3;HSkMC: 61.2;hTEC/SVTERT24-B: 64.3;hTERT-RPE1: 55.8;LHCN-M2: 64.3;TIME: 207.9;U-138 MG: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" NA NA 28000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (7.77e-2)" "unprognostic (2.01e-4)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (6.41e-2)" "unprognostic (7.29e-3)" "unprognostic (2.58e-2)" "unprognostic (1.87e-1)" "unprognostic (6.59e-2)" "unprognostic (1.50e-2)" 3.9 5.5 1.0 1.9 0.9 0.0 2.4 1.7 1.1 3.8 0.0 3.0 1.8 13.3 1.1 5.4 4.0 4.9 1.0 3.6 1.8 2.1 0.9 1.2 0.8 2.1 3.3 1.5 1.4 0.2 1.8 0.6 0.5 8.1 2.9 0.4 1.3 1.6 0.4 0.9 1.8 11.2 1.4 0.7 5.1 1.0 9.6 0.5 0.9 0.8 0.9 2.6 2.0 1.0 6.4 0.5 1.2 0.0 17.5 118.3 0.0 3.6 16.3 14.8 33.3 0.0 0.1 0.1 0.1 44.1 5.5 0.0 6.6 1.1 41.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 61.2 0.0 64.3 0.2 55.8 27.1 0.0 0.1 0.3 64.3 0.0 0.2 0.1 5.6 0.0 0.3 0.0 10.1 0.2 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 207.9 96.9 2.5 2.6 15.8 0.0 0.0 0.0 31.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.7 1.1 3.6 1.8 2.1 3.3 0.5 1.4 9.6 1.0 1.6 0.0 0.0 5.2 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.4 1.4 0.0 0.6 0.0 0.0 0.0 0.0 3.1 0.0 0.1 7.2 0.3 1.1 8.9 0.0 0.0 245.4 0.0 0.0 15.1 0.5 0.5 0.0 0.1 1.1 0.0 0.1 0.0 39.5 0.4 0.0 0.0 0.8 2.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 9.0 5.7 0.0 0.4 1.2 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.1 1.2 2.9 1.6 0.1 0.1 0.1 0.0 0.1 1.7 0.1 ADAMTSL2 KIAA0605 ENSG00000197859 "ADAMTS like 2" Q86TH1 9 133532164-133575519 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.2;liver: 35.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Endothelial cells: 5.7;Fibroblasts: 8.5;Microglial cells: 12.2;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 7.4;RPMI-8226: 10.1;SH-SY5Y: 30.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045634, HPA053812" Approved Approved Vesicles "Secreted in other tissues" NA NA 170000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA045634: AB_2679399, HPA053812: AB_2682271" "unprognostic (5.10e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.35e-2)" "unprognostic (1.07e-1)" "unprognostic (5.50e-2)" "unprognostic (6.78e-3)" "unprognostic (1.31e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.17e-2)" "unprognostic (7.37e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" 3.7 28.5 6.8 1.0 7.3 0.1 1.5 12.0 10.1 2.3 1.4 2.7 1.4 3.1 3.1 1.8 3.1 2.5 73.2 5.8 7.9 25.9 35.8 23.2 3.4 19.3 11.1 4.9 7.1 1.2 15.9 1.5 20.8 8.4 0.3 0.3 3.4 2.2 4.3 0.8 3.2 0.9 8.5 6.4 2.3 3.1 9.3 0.6 12.1 0.5 0.6 5.3 1.6 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.6 0.5 0.0 1.1 0.7 10.1 0.0 0.0 1.4 30.1 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 7.3 12.0 10.1 5.8 7.9 19.3 11.1 20.8 8.5 9.3 7.6 1.4 0.0 0.5 4.9 0.1 0.1 0.1 0.0 0.0 4.2 0.0 0.1 2.3 0.0 0.0 1.8 0.0 0.1 0.0 1.4 5.9 0.2 0.1 0.1 0.1 5.7 5.3 0.0 5.0 0.0 0.1 8.5 0.0 0.0 0.0 0.1 4.6 0.9 0.3 0.0 3.8 0.4 0.0 0.3 0.8 1.1 4.7 0.6 0.0 12.2 0.0 0.4 0.0 2.5 4.0 0.2 0.5 3.0 0.0 0.2 0.0 0.7 0.0 0.2 6.6 1.1 1.6 0.1 0.8 0.4 0.3 0.0 0.6 0.7 1.1 0.2 ADAMTSL3 "KIAA1233, punctin-2" ENSG00000156218 "ADAMTS like 3" P82987 15 83654088-84039842 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 141.1;Alveolar cells type 2: 111.8;Astrocytes: 86.5;Club cells: 61.7;granulocytes: 63.1;Inhibitory neurons: 91.6;Oligodendrocytes: 75.2;Respiratory ciliated cells: 56.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 12.1;hTERT-RPE1: 3.6;RPTEC TERT1: 14.0;TIME: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034773, HPA034774" Uncertain Uncertain Vesicles "Secreted in other tissues" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034773: AB_10601965, HPA034774: AB_2674326" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (9.89e-2)" "unprognostic (4.07e-2)" "unprognostic (3.27e-1)" "unprognostic (9.18e-3)" "unprognostic (5.92e-2)" "unprognostic (9.97e-2)" "unprognostic (3.85e-1)" "unprognostic (8.59e-3)" "unprognostic (5.00e-3)" "unprognostic (4.62e-1)" "unprognostic (8.64e-2)" "unprognostic (3.95e-5)" 6.3 4.2 1.1 1.0 1.7 0.0 1.7 1.4 1.0 3.1 4.4 10.6 1.4 6.9 1.5 3.3 4.4 1.1 10.7 1.1 1.1 3.3 10.4 7.4 1.1 1.4 1.5 1.2 7.3 0.8 1.4 10.4 1.7 6.6 3.2 0.3 2.4 7.1 2.6 1.4 1.8 4.7 1.5 1.9 4.6 2.7 1.1 1.0 2.6 4.8 0.5 5.2 2.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.9 0.0 14.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 0.0 0.0 13.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 1.4 1.0 1.1 1.1 1.4 1.5 1.7 1.5 1.1 3.0 8.7 141.1 111.8 86.5 0.1 7.0 5.2 1.7 0.6 0.2 0.2 0.3 9.4 0.0 61.7 1.8 0.0 0.1 0.8 0.0 0.0 0.5 14.9 0.6 0.4 10.6 0.0 0.0 31.3 2.4 0.2 29.0 1.5 1.2 63.1 0.1 1.1 10.2 0.2 6.7 91.6 0.0 0.0 0.6 0.5 16.9 49.4 5.9 0.0 5.6 0.0 0.1 1.0 4.5 75.2 1.0 0.0 17.0 0.4 2.4 0.0 0.6 56.4 0.2 26.3 13.0 8.3 2.1 2.8 0.6 1.1 0.1 5.0 0.4 0.0 2.3 ADAMTSL4 "DKFZP434K1772, TSRC1" ENSG00000143382 "ADAMTS like 4" Q6UY14 1 150549369-150560937 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 146.7;Endometrial stromal cells: 36.9;Extravillous trophoblasts: 46.4;Fibroblasts: 34.5;Hofbauer cells: 34.0;Syncytiotrophoblasts: 99.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 11.1" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 92.0;BEWO: 200.3;HSkMC: 43.8;K-562: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA006279 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA006279: AB_1078102" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (8.09e-4)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.56e-2)" "unprognostic (1.68e-2)" "unprognostic (1.28e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.44e-2)" "unprognostic (7.40e-3)" 32.0 5.1 1.1 14.9 1.0 4.2 24.7 0.8 11.1 22.9 7.9 19.3 3.6 20.0 1.6 33.3 29.2 7.7 22.3 0.8 1.4 6.4 17.3 26.1 1.8 4.4 2.8 17.1 3.0 0.5 3.0 62.9 2.9 9.0 3.8 0.6 11.8 3.4 37.7 11.8 13.7 11.4 1.2 5.4 17.2 2.4 3.6 0.8 6.1 47.9 1.2 32.8 23.3 1.5 22.0 0.6 0.3 3.9 19.1 92.0 200.3 20.8 18.0 12.1 7.0 1.8 8.5 0.2 4.3 14.4 0.2 11.0 0.8 3.2 4.9 1.7 0.4 6.2 2.6 8.9 15.3 0.3 3.0 43.8 0.9 3.0 6.8 10.3 0.1 0.0 67.7 0.7 2.2 0.5 0.0 1.1 3.5 0.6 0.7 0.0 0.0 0.1 2.1 0.8 0.1 0.6 6.7 15.9 0.1 10.0 4.5 11.5 3.8 0.7 5.5 8.6 0.3 1.9 0.6 4.5 0.8 4.0 0.5 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.3 1.1 1.0 0.8 11.1 0.8 1.4 4.4 2.8 2.9 1.2 3.6 1.5 2.8 0.0 1.5 1.0 0.5 2.4 2.3 0.2 0.6 1.7 1.3 1.8 2.2 10.0 0.6 0.0 0.0 146.7 1.0 0.2 0.0 1.7 0.6 2.6 36.9 5.3 0.0 0.0 0.3 0.6 46.4 34.5 0.0 5.4 2.5 0.9 1.8 10.6 34.0 0.0 0.1 0.2 0.0 24.0 12.5 0.7 30.1 20.0 3.6 0.0 23.1 1.4 1.0 0.0 0.0 12.3 0.1 3.4 3.2 2.2 0.0 0.2 0.9 2.2 0.0 14.3 3.8 0.1 1.6 5.5 2.8 99.5 1.7 0.5 0.3 2.5 ADAMTSL5 THSD6 ENSG00000185761 "ADAMTS like 5" 19 1505022-1513604 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 33.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 9.8;Cardiomyocytes: 9.6;Leydig cells: 19.3;Peritubular cells: 18.0;Proximal enterocytes: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044050 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA044050: AB_10962625" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (5.85e-2)" "unprognostic (2.45e-1)" "unprognostic (1.10e-2)" "unprognostic (1.44e-1)" "unprognostic (1.17e-2)" "unprognostic (1.77e-2)" "unprognostic (1.89e-1)" "unprognostic (2.79e-2)" "unprognostic (2.89e-3)" "unprognostic (1.52e-1)" "unprognostic (5.03e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.37e-3)" 1.8 1.5 1.7 0.7 2.2 0.3 2.2 2.3 2.0 33.0 8.3 3.2 9.8 19.8 5.0 15.1 9.5 0.5 20.7 1.8 0.4 1.5 4.2 1.4 0.6 0.8 1.0 1.3 1.0 1.4 2.6 4.2 0.6 4.5 1.1 0.9 3.9 3.3 15.1 2.1 8.4 12.5 0.2 0.8 1.4 3.6 1.6 0.2 1.5 5.9 1.5 3.8 22.5 1.4 8.1 3.5 0.1 0.1 4.1 3.0 3.8 14.7 9.8 5.6 8.1 20.7 4.0 0.0 3.6 12.3 1.6 6.7 3.5 4.2 4.2 7.9 0.4 1.7 11.0 3.8 4.6 0.2 10.2 1.8 4.6 1.3 3.5 7.4 0.0 2.5 5.0 9.8 0.6 7.5 0.4 0.4 0.1 2.3 1.8 0.2 0.8 2.1 4.5 0.0 0.1 0.3 3.5 0.4 4.4 1.9 9.2 3.0 0.9 0.0 5.4 10.9 0.6 6.2 4.2 1.0 0.1 0.8 2.4 0.2 0.0 0.4 1.4 0.5 0.9 0.0 1.6 1.1 0.0 0.0 2.0 1.3 0.1 0.0 0.9 0.0 0.5 0.5 1.7 2.2 2.3 2.0 1.8 0.4 0.8 1.0 0.6 0.2 1.6 1.4 0.2 0.0 1.1 3.6 0.3 0.4 2.4 9.8 6.2 0.3 1.9 0.8 9.6 0.0 3.4 0.0 0.0 0.8 0.7 0.6 0.0 0.6 0.6 0.3 4.5 0.4 0.0 0.0 0.1 1.7 2.1 5.8 1.1 0.4 0.0 0.5 0.0 1.8 0.3 0.0 0.1 1.8 4.1 0.0 0.4 2.6 19.3 0.4 1.8 1.0 0.0 3.7 0.0 0.0 0.1 7.0 1.5 18.0 1.8 2.7 12.5 0.5 1.3 2.1 0.0 0.9 3.3 0.6 1.9 8.4 0.4 0.7 1.2 0.3 1.6 3.5 ADARB2 "ADAR3, hRED2, RED2" ENSG00000185736 "Adenosine deaminase RNA specific B2 (inactive)" Q9NS39 10 1177313-1737525 "Predicted intracellular proteins" "mRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 46.7" "Group enriched" "Detected in many" 4 "Inhibitory neurons: 1726.7;Oligodendrocyte precursor cells: 693.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 4.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.83e-1)" "unprognostic (4.73e-3)" "unprognostic (4.64e-2)" "unprognostic (7.44e-3)" "unprognostic (2.12e-1)" "unprognostic (2.62e-2)" "unprognostic (2.53e-1)" "unprognostic (1.27e-2)" "unprognostic (1.89e-1)" "unprognostic (9.58e-2)" "unprognostic (9.28e-3)" "unprognostic (3.41e-1)" "unprognostic (3.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.04e-1)" "unprognostic (3.11e-1)" "unprognostic (3.81e-3)" 0.1 0.2 18.8 0.0 25.9 0.2 0.8 15.6 18.1 0.7 0.2 2.3 0.1 0.2 0.0 0.3 1.1 0.0 0.4 12.9 20.7 0.3 0.1 0.6 0.2 21.7 20.2 0.1 3.5 0.0 0.4 0.1 21.7 0.5 0.0 3.0 4.2 0.8 0.0 0.3 0.8 0.0 16.4 0.1 0.7 2.9 29.7 1.0 0.1 0.1 0.4 0.6 0.5 46.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.2 0.1 4.7 1.1 0.0 0.0 0.4 0.1 18.8 25.9 15.6 18.1 12.9 20.7 21.7 20.2 21.7 16.4 29.7 46.7 0.3 0.0 0.0 57.8 0.7 0.0 0.1 0.0 4.6 11.1 1.7 0.6 1.9 2.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 40.9 1.6 0.1 0.5 0.0 0.0 9.2 0.0 0.0 0.3 0.5 0.3 0.0 4.8 4.6 0.0 0.2 1.7 1726.7 0.0 0.0 0.0 0.0 133.9 0.3 0.0 3.6 6.5 0.0 30.5 2.1 693.7 254.6 0.0 0.0 0.4 0.0 0.1 0.1 2.9 0.0 1.4 6.6 0.0 0.4 1.2 1.0 3.3 0.0 0.0 0.6 0.2 0.3 0.1 ADAT1 ENSG00000065457 "Adenosine deaminase tRNA specific 1" Q9BUB4 16 75596868-75623300 "Enzymes, Predicted intracellular proteins" "tRNA processing" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 101.9;Late spermatids: 213.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040713, HPA040903" Approved Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA040713: AB_10795371, HPA040903: AB_10794071" "unprognostic (7.71e-3)" "unprognostic (5.35e-2)" "unprognostic (7.62e-2)" "unprognostic (9.00e-2)" "unprognostic (9.99e-2)" "unprognostic (4.69e-2)" "unprognostic (4.54e-2)" "unprognostic (6.65e-3)" "unprognostic (3.38e-1)" "unprognostic (1.14e-2)" "unprognostic (9.75e-2)" "unprognostic (2.97e-1)" "unprognostic (4.60e-3)" "unprognostic (7.21e-2)" "unprognostic (4.92e-1)" "unprognostic (5.58e-3)" "unprognostic (8.27e-2)" 13.8 16.4 11.0 9.5 11.1 7.8 14.1 11.5 15.1 12.0 10.5 11.6 5.1 14.0 12.7 11.7 11.8 6.6 11.5 10.8 10.5 19.8 18.5 12.8 10.8 11.5 11.2 10.3 12.6 14.6 14.2 7.3 11.7 15.3 9.1 9.6 12.1 8.6 9.5 14.1 14.0 6.0 10.6 20.4 12.0 26.9 11.5 11.8 14.8 5.2 8.7 13.1 11.6 13.0 14.7 23.1 15.0 15.5 26.4 20.3 11.5 20.2 21.0 26.1 17.7 15.4 22.4 15.7 19.8 20.6 14.0 17.6 16.4 25.0 24.6 11.7 8.6 8.8 16.0 13.3 21.2 19.6 19.6 21.7 23.8 42.7 32.1 7.5 23.1 24.7 13.7 7.6 21.2 35.9 18.8 14.3 12.2 19.8 10.7 23.6 12.1 21.5 24.6 22.0 18.1 18.6 47.8 12.2 11.2 15.0 24.6 9.3 16.3 32.4 14.6 17.1 16.9 15.1 24.3 58.9 16.3 15.6 28.5 8.5 4.3 11.5 8.5 6.4 11.3 7.9 7.3 11.3 5.8 7.3 4.5 6.3 4.9 10.8 9.9 4.6 9.0 6.2 11.0 11.1 11.5 15.1 10.8 10.5 11.5 11.2 11.7 10.6 11.5 13.0 9.9 9.6 5.8 2.3 11.6 4.6 5.9 5.7 6.8 13.5 10.7 6.6 5.6 11.5 6.6 7.3 27.1 11.8 9.8 6.8 17.6 8.6 101.9 11.8 8.2 11.9 14.4 16.0 6.0 7.6 8.9 6.4 8.6 10.5 8.2 12.6 6.1 10.5 10.3 13.5 6.4 4.7 10.2 14.4 10.6 213.0 9.9 10.2 3.6 2.8 12.8 7.8 15.5 3.0 8.0 9.8 3.3 7.9 8.1 8.3 6.9 11.3 9.9 21.6 6.6 6.8 7.0 17.5 13.4 8.4 5.4 9.7 14.8 12.9 9.1 7.6 ADCK1 FLJ39600 ENSG00000063761 "AarF domain containing kinase 1" Q86TW2 14 77800109-77935014 "Enzymes, Predicted secreted proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.9;Oligodendrocytes: 29.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051012, HPA055014" Uncertain Uncertain Nucleoplasm "Secreted - unknown location" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA051012: AB_2681310, HPA055014: AB_2682672" "unprognostic (6.36e-2)" "unprognostic (7.09e-2)" "unprognostic (6.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.70e-4)" "prognostic favorable (4.11e-5)" "unprognostic (2.33e-1)" "unprognostic (1.64e-1)" "unprognostic (4.57e-3)" "unprognostic (1.38e-1)" "prognostic favorable (5.82e-6)" "unprognostic (6.30e-3)" "unprognostic (2.06e-1)" "unprognostic (9.57e-2)" "unprognostic (4.06e-1)" 4.4 8.1 7.3 3.7 7.8 5.3 4.2 7.3 10.3 4.3 8.2 6.7 7.4 4.8 5.1 6.1 4.4 3.8 9.0 7.8 7.2 7.0 8.6 4.0 4.1 7.8 7.4 4.7 6.7 6.5 8.3 5.1 8.2 6.5 5.8 3.8 6.7 5.4 8.9 6.3 5.6 6.4 7.1 7.3 6.1 4.6 7.9 5.2 5.9 5.2 4.8 5.1 4.0 10.2 5.5 9.1 4.4 17.4 13.0 6.5 6.2 5.7 7.9 4.5 5.6 4.7 12.4 12.0 8.5 9.5 7.5 10.2 27.0 9.3 2.9 6.3 9.1 2.8 4.9 7.5 12.2 4.5 6.6 7.7 16.2 1.9 5.7 4.4 7.1 10.1 11.4 7.4 5.9 24.5 5.8 7.6 9.6 17.5 10.2 9.1 0.7 9.0 6.6 13.9 10.4 6.0 10.6 14.7 5.9 6.8 20.9 9.4 6.8 4.6 3.4 8.9 4.6 6.4 7.7 6.3 6.6 7.7 5.8 1.3 4.0 1.4 4.2 6.0 2.9 1.4 1.6 2.4 7.4 3.0 1.9 3.4 0.3 3.2 2.5 5.5 3.1 2.5 7.3 7.8 7.3 10.3 7.8 7.2 7.8 7.4 8.2 7.1 7.9 10.2 1.9 0.0 3.7 10.1 1.8 0.9 1.8 3.9 2.8 5.9 2.9 3.0 5.7 4.3 2.8 0.0 20.9 8.2 4.2 4.0 3.9 4.4 1.5 2.0 2.4 1.4 1.8 2.1 10.3 5.1 4.2 2.4 6.6 2.4 1.3 5.0 1.8 6.6 9.6 8.4 11.7 4.0 4.1 4.4 1.5 0.8 1.5 5.1 0.0 5.6 2.5 4.0 3.1 11.6 29.0 2.8 1.3 1.9 3.2 1.5 3.0 3.8 2.4 9.3 0.0 2.1 1.6 1.8 9.9 4.3 1.4 5.3 2.2 4.6 5.4 1.2 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 ADCY7 "AC7, KIAA0037" ENSG00000121281 "Adenylate cyclase 7" P51828 16 50246137-50318135 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 42.8;granulocytes: 50.6;Kupffer cells: 65.1;Langerhans cells: 48.0;Macrophages: 45.4;Microglial cells: 52.5;monocytes: 42.4;NK-cells: 76.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 81.0;HMC-1: 194.6;RPMI-8226: 100.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041218, HPA048241" Uncertain Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA041218: AB_2677365, HPA048241: AB_2680326" "unprognostic (1.98e-1)" "prognostic unfavorable (5.31e-4)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (3.77e-1)" "unprognostic (2.80e-1)" "unprognostic (3.90e-2)" "unprognostic (7.75e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (5.59e-3)" "unprognostic (7.34e-2)" "unprognostic (2.15e-3)" "unprognostic (2.18e-1)" "unprognostic (9.52e-4)" 8.1 3.9 6.8 23.9 7.3 24.7 5.6 7.8 8.8 3.9 6.9 8.2 4.1 3.7 2.3 14.3 7.6 12.4 5.5 6.2 10.6 1.6 3.8 23.3 27.1 14.4 11.4 19.4 2.0 1.6 2.0 14.5 12.8 2.7 8.8 0.8 4.0 2.1 2.2 13.7 8.6 7.8 10.9 29.7 7.8 1.9 12.9 19.3 2.4 3.5 24.5 7.6 4.7 19.1 16.3 18.5 0.7 2.6 1.9 24.0 1.7 9.7 4.5 8.1 7.0 23.4 28.4 4.2 25.4 41.0 0.5 50.5 22.3 10.0 8.9 50.7 6.9 81.0 18.4 5.8 20.6 10.6 194.6 12.0 8.5 5.7 8.3 4.4 2.3 17.7 30.4 7.9 10.5 9.2 5.8 34.9 3.5 8.4 31.1 5.7 7.1 100.6 5.0 1.1 4.0 9.8 5.4 2.0 4.8 4.4 0.1 38.7 17.6 0.9 25.5 2.9 3.6 0.3 0.6 8.5 9.3 32.6 3.4 9.2 7.6 2.8 6.9 10.7 5.1 2.8 2.9 5.2 12.2 3.3 2.5 3.6 4.1 9.5 18.1 6.8 4.4 5.6 6.8 7.3 7.8 8.8 6.2 10.6 14.4 11.4 12.8 10.9 12.9 19.1 1.4 19.2 35.9 2.0 15.4 3.7 0.4 0.6 1.2 1.2 1.3 2.8 1.0 0.0 7.9 0.0 6.2 11.6 42.8 3.3 0.0 1.9 1.5 6.7 6.5 1.9 0.0 12.4 6.4 0.2 1.8 9.2 3.6 13.6 50.6 4.7 1.4 0.5 35.2 0.0 3.8 0.7 0.0 65.1 48.0 1.3 0.6 45.4 5.4 52.5 42.4 0.5 76.2 3.5 0.7 4.2 10.4 1.2 15.6 0.5 0.1 0.2 1.0 0.8 6.6 28.3 2.2 0.0 1.5 7.2 4.0 4.0 26.6 16.0 2.3 1.3 ADCYAP1 PACAP ENSG00000141433 "Adenylate cyclase activating polypeptide 1" P18509 18 904871-912172 "Predicted secreted proteins" Neurogenesis Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.9;lymphoid tissue: 10.9" "Group enriched" "Detected in some" 6 "Excitatory neurons: 13.4;granulocytes: 43.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "SCLC-21H: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065887 Supported Supported "Secreted in other tissues" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA065887: " "unprognostic (2.68e-1)" "unprognostic (1.83e-2)" "unprognostic (7.09e-2)" "unprognostic (4.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.87e-4)" "unprognostic (9.58e-3)" "unprognostic (1.00e-1)" "unprognostic (2.34e-1)" "unprognostic (6.86e-2)" "unprognostic (4.16e-2)" "unprognostic (9.94e-2)" "prognostic favorable (2.91e-6)" "unprognostic (2.24e-3)" "unprognostic (9.22e-2)" "unprognostic (1.74e-1)" "unprognostic (5.74e-4)" 1.8 0.2 1.9 10.9 2.6 0.0 1.3 0.3 2.9 2.1 0.0 1.8 0.1 3.0 0.0 1.3 0.4 7.1 0.5 2.7 21.7 0.5 0.2 1.6 1.0 31.9 6.8 0.1 4.8 0.2 3.5 0.1 13.7 1.4 1.1 0.3 1.9 0.5 0.2 0.7 1.3 1.0 5.4 0.1 1.5 2.5 17.7 0.4 0.2 0.0 1.0 2.3 1.3 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.6 0.3 2.9 2.7 21.7 31.9 6.8 13.7 5.4 17.7 2.0 0.2 3.2 0.6 0.3 0.0 0.6 0.1 0.1 0.0 0.5 0.1 0.0 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.5 0.0 0.0 13.4 0.0 0.0 2.4 0.0 0.0 43.1 0.0 0.4 0.0 0.1 0.0 0.5 0.0 4.1 0.0 0.9 1.5 0.3 0.2 0.0 1.9 0.0 0.2 0.0 0.5 1.1 2.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 2.6 0.0 0.0 0.4 0.0 2.0 0.0 0.0 0.2 ADCYAP1R1 "PAC1, PAC1R, PACAPR" ENSG00000078549 "ADCYAP receptor type I" P41586 7 31052308-31111479 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 148.0" "Group enriched" "Detected in some" 4 "Astrocytes: 57.1;Inhibitory neurons: 45.7" "Cancer enriched" "Detected in some" 11 "glioma: 45.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.7;NTERA-2: 4.8;SCLC-21H: 4.1;SH-SY5Y: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030739, HPA049877" Enhanced Enhanced Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA030739: AB_2732461, HPA049877: AB_2680928" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.16e-2)" "prognostic favorable (5.78e-4)" "unprognostic (2.17e-1)" "unprognostic (8.36e-2)" "unprognostic (4.93e-2)" "unprognostic (5.75e-2)" "unprognostic (3.50e-2)" "unprognostic (3.88e-1)" "unprognostic (1.58e-1)" "unprognostic (6.67e-3)" "unprognostic (6.43e-4)" "unprognostic (1.09e-3)" "unprognostic (9.55e-2)" "unprognostic (3.85e-2)" "unprognostic (2.75e-4)" 7.4 11.4 91.8 2.3 79.8 0.0 4.0 53.4 57.6 13.1 3.5 7.1 0.8 5.3 1.5 2.9 29.5 1.3 3.8 69.7 106.5 0.1 0.2 0.8 0.1 96.0 102.7 1.8 1.6 1.6 9.8 0.0 88.9 1.8 1.3 2.7 2.2 3.2 1.3 1.1 2.2 3.7 67.9 0.5 3.5 1.6 148.0 0.8 2.1 8.0 0.8 1.8 4.3 43.7 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 7.4 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.6 0.8 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.8 79.8 53.4 57.6 69.7 106.5 96.0 102.7 88.9 67.9 148.0 43.7 4.2 0.0 0.0 57.1 0.0 0.5 0.0 0.0 0.0 1.7 0.2 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.2 0.7 0.0 0.0 10.8 0.0 0.0 4.6 0.0 6.3 0.0 1.2 0.0 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.7 0.9 11.5 0.0 1.8 2.8 0.0 0.0 0.0 11.6 1.5 0.0 0.0 5.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 5.8 0.3 1.5 0.0 0.3 0.0 0.2 0.1 0.0 0.1 ADGRA3 "FLJ38547, GPR125, PGR21" ENSG00000152990 "Adhesion G protein-coupled receptor A3" Q8IWK6 4 22345071-22516066 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.3" "Cell type enhanced" "Detected in many" "Astrocytes: 221.7;Hepatocytes: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 74.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008904 Uncertain "Intracellular and membrane" NA NA 280000 "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA008904: AB_1849258" "unprognostic (3.70e-1)" "unprognostic (9.01e-2)" "unprognostic (5.32e-3)" "unprognostic (8.27e-3)" "unprognostic (4.58e-2)" "unprognostic (1.55e-1)" "unprognostic (8.15e-2)" "unprognostic (1.81e-2)" "unprognostic (1.02e-1)" "unprognostic (3.91e-2)" "unprognostic (8.77e-2)" "unprognostic (1.88e-1)" "unprognostic (1.78e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.79e-3)" 8.1 9.5 22.9 3.7 21.5 1.9 10.9 21.6 19.2 10.9 43.8 17.1 7.2 15.1 9.6 5.2 21.6 7.6 10.8 21.8 27.2 10.4 58.3 5.0 1.2 24.5 34.7 8.9 12.5 12.2 7.3 9.2 24.2 12.0 17.1 5.9 8.2 11.5 17.6 4.4 7.0 14.0 26.8 2.7 9.6 6.8 25.6 5.1 25.1 11.4 2.6 5.7 4.9 24.1 19.6 14.4 36.5 30.6 29.0 13.0 32.7 23.5 25.7 15.5 8.4 16.5 38.1 3.0 11.7 11.2 21.5 21.1 23.2 33.4 22.1 0.0 16.3 1.7 11.3 37.0 9.7 17.1 0.0 12.3 40.9 10.1 17.5 29.5 23.7 12.2 17.9 0.6 26.1 8.7 15.3 0.5 40.3 18.3 14.6 70.7 74.6 4.9 18.8 19.9 27.1 31.3 9.8 0.8 16.7 25.1 10.1 14.8 0.5 23.2 16.6 10.6 22.4 2.7 0.0 0.1 12.7 12.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 22.9 21.5 21.6 19.2 21.8 27.2 24.5 34.7 24.2 26.8 25.6 24.1 2.4 3.2 4.1 221.7 1.1 0.0 13.4 0.0 11.4 11.8 12.0 14.6 14.5 21.5 5.0 16.5 20.9 21.8 2.3 18.8 0.0 18.4 7.9 50.1 23.2 3.1 12.2 9.1 12.3 11.8 7.9 10.2 10.2 41.4 0.0 28.5 6.1 120.4 3.4 0.0 18.9 18.8 0.0 5.4 0.0 7.4 9.6 1.8 0.0 9.4 0.4 6.2 0.0 54.3 3.5 20.3 12.2 9.8 0.2 21.0 10.6 5.4 2.2 13.5 0.0 25.7 8.0 1.3 7.2 2.5 0.0 7.3 1.3 11.7 22.2 11.1 ADGRB2 BAI2 ENSG00000121753 "Adhesion G protein-coupled receptor B2" O60241 1 31727117-31764893 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 61.4" "Cell type enhanced" "Detected in many" "Astrocytes: 20.9;Bipolar cells: 16.0;Excitatory neurons: 55.7;Inhibitory neurons: 13.8;Oligodendrocyte precursor cells: 20.6;Oligodendrocytes: 13.2" "Cancer enriched" "Detected in many" 4 "glioma: 20.5" "Region enhanced" "Detected in many" "hippocampal formation: 61.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 37.7;SH-SY5Y: 25.1;T-47d: 29.5;U-2 OS: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069175 Supported "Plasma membrane" NA NA 32000 "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA069175: " "prognostic favorable (6.46e-4)" "unprognostic (1.74e-1)" "unprognostic (7.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.90e-1)" "unprognostic (2.40e-1)" "unprognostic (8.17e-4)" "prognostic unfavorable (4.02e-5)" "unprognostic (2.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.80e-3)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (1.75e-3)" "unprognostic (7.98e-2)" 1.5 3.8 30.6 0.4 30.1 0.2 1.3 0.0 41.1 2.4 0.0 1.6 4.0 2.9 0.2 0.6 1.3 1.1 4.5 61.4 0.0 0.8 0.0 0.7 0.4 0.0 0.2 1.5 0.5 1.2 8.0 2.7 0.0 1.9 0.1 2.9 0.5 1.8 0.7 0.7 3.8 1.3 0.0 0.8 1.1 2.9 1.0 8.7 2.7 0.4 0.2 1.5 1.0 12.2 1.0 7.5 6.9 20.1 1.9 1.2 3.3 4.8 7.6 4.6 8.1 0.4 2.3 0.0 4.7 2.1 7.7 0.8 3.1 0.4 0.8 5.4 3.2 0.0 37.7 0.0 0.1 0.0 2.6 1.2 0.5 6.4 0.0 14.4 0.7 14.7 0.8 0.2 5.2 0.6 13.9 0.1 8.7 0.2 2.1 20.8 0.8 0.7 0.0 9.7 5.2 25.1 11.0 0.7 0.8 2.4 29.5 0.0 0.2 3.6 27.5 0.5 1.3 0.0 0.0 0.8 11.0 0.1 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.6 30.1 0.0 41.1 61.4 0.0 0.0 0.2 0.0 0.0 1.0 12.2 0.1 0.0 0.0 20.9 0.3 0.0 0.5 0.0 0.0 16.0 2.0 1.3 4.3 0.0 0.0 0.0 6.2 1.0 1.2 0.0 0.0 0.1 3.6 1.4 0.6 0.1 1.2 0.0 55.7 0.0 1.4 2.3 0.5 0.4 0.0 1.5 0.0 0.0 0.4 8.4 13.8 0.9 0.0 0.0 0.0 12.0 1.2 0.0 0.0 4.7 0.0 11.4 4.1 20.6 13.2 0.1 0.1 1.9 0.1 0.5 5.7 2.5 0.0 5.2 0.0 1.4 0.7 0.9 4.5 0.0 0.0 0.3 0.4 0.8 0.5 1.3 ADGRD1 "DKFZp434B1272, GPR133, PGR25" ENSG00000111452 "Adhesion G protein-coupled receptor D1" Q6QNK2 12 130953907-131141469 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 62.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 22.4;Alveolar cells type 2: 30.5;Cardiomyocytes: 47.0;Early spermatids: 16.2;Endometrial stromal cells: 50.2;Fibroblasts: 32.7;Late spermatids: 21.4;Leydig cells: 13.7;Microglial cells: 25.3;Peritubular cells: 15.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.0;intermediate monocyte: 2.3;myeloid DC: 1.1;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;monocytes: 2.3" "Cell line enhanced" "Detected in some" "BJ: 4.1;fHDF/TERT166: 4.7;HeLa: 7.6;HHSteC: 4.9;HMC-1: 13.0;U-2 OS: 6.1" "Region enhanced" "Detected in some" "basal ganglia: 5.1" "Low region specificity" "Detected in all" "HPA042395, HPA076279" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane" "HPA042395: AB_10796906, HPA076279: " "unprognostic (3.21e-1)" "unprognostic (1.49e-4)" "unprognostic (1.32e-2)" "unprognostic (1.63e-1)" "unprognostic (4.40e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (9.27e-4)" "unprognostic (2.55e-3)" "unprognostic (1.63e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-2)" "unprognostic (3.98e-2)" "unprognostic (4.79e-5)" "unprognostic (1.31e-3)" "unprognostic (4.58e-1)" "unprognostic (2.15e-2)" "unprognostic (1.77e-3)" 26.4 1.9 1.9 1.3 2.0 0.3 10.3 1.2 2.5 20.6 1.0 10.6 1.9 15.4 7.3 6.9 17.7 12.9 62.4 1.4 3.2 3.4 10.3 35.6 0.4 2.0 2.6 17.9 12.0 0.3 6.3 25.7 2.2 15.3 1.8 0.8 2.9 1.0 7.3 7.0 12.1 7.1 2.0 2.3 20.7 7.5 3.6 0.4 11.2 8.5 1.0 40.3 16.3 1.7 0.0 0.7 0.0 2.0 0.0 0.0 0.1 4.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.6 0.0 4.9 0.0 13.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.8 0.0 0.1 0.2 2.1 0.5 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.4 6.1 1.5 0.1 0.1 1.7 0.8 0.1 0.0 0.0 0.0 2.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 1.9 2.0 1.2 2.5 1.4 3.2 2.0 2.6 2.2 2.0 3.6 1.7 2.0 22.4 30.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 47.0 0.0 5.0 1.8 0.0 1.3 0.0 0.0 0.0 0.0 16.2 1.3 50.2 3.4 0.0 0.0 1.1 0.4 0.6 32.7 0.5 1.0 1.3 0.3 1.8 3.6 2.3 0.0 1.4 0.0 0.0 1.5 0.0 21.4 13.7 1.5 0.0 25.3 3.5 0.0 0.0 0.0 0.1 0.3 0.0 15.8 0.0 0.0 0.0 0.1 2.2 0.7 6.6 2.2 3.5 4.3 6.5 0.1 0.0 1.0 0.6 0.2 0.1 0.3 ADGRE3 EMR3 ENSG00000131355 "Adhesion G protein-coupled receptor E3" Q9BY15 19 14619117-14690027 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.1;lymphoid tissue: 6.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.4;Astrocytes: 2.0;Excitatory neurons: 1.9;granulocytes: 2.5;Inhibitory neurons: 2.4;Macrophages: 8.0;Microglial cells: 3.7;monocytes: 3.2;Oligodendrocytes: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 281.6;eosinophil: 509.0;neutrophil: 489.4" "Lineage enriched" "Detected in many" 8 "granulocytes: 509.0" "Cell line enriched" "Detected in some" 36 "HMC-1: 43.3" "Not detected" "Not detected" HPA015638 Uncertain "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA015638: AB_1848039" "unprognostic (2.11e-4)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (5.69e-2)" "unprognostic (5.63e-2)" "unprognostic (4.53e-2)" "unprognostic (1.14e-1)" "unprognostic (8.07e-2)" "unprognostic (9.61e-2)" "unprognostic (9.11e-4)" "unprognostic (4.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.13e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" 1.2 0.1 0.0 6.1 0.0 3.1 0.0 0.0 0.5 0.2 0.0 0.4 1.6 0.1 0.0 0.3 0.3 1.0 0.1 0.0 0.0 0.1 0.6 2.5 0.3 0.1 0.0 0.0 0.4 0.0 0.0 0.5 0.2 0.2 0.5 0.0 1.8 0.0 0.0 0.0 2.3 0.7 0.0 5.9 0.5 0.1 0.1 0.4 0.1 1.0 2.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 281.6 21.8 509.0 0.0 52.9 0.1 0.6 0.2 0.0 5.3 0.1 0.1 0.1 489.4 0.0 61.3 0.3 0.1 7.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 2.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.5 0.0 2.5 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.6 0.0 0.0 0.0 8.0 0.0 3.7 3.2 0.0 0.0 1.5 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 ADGRE5 "CD97, TM7LN1" ENSG00000123146 "Adhesion G protein-coupled receptor E5" P48960 19 14380501-14408725 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 211.6" "Cell type enhanced" "Detected in many" "dendritic cells: 245.4;Kupffer cells: 111.1;Macrophages: 131.6;NK-cells: 160.6;Plasma cells: 141.5;T-cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013707 Enhanced Approved Cytosol "Secreted to blood" NA Yes 10000000 2400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA013707: AB_1846345" "unprognostic (3.16e-1)" "unprognostic (1.80e-1)" "unprognostic (5.10e-2)" "unprognostic (2.30e-1)" "unprognostic (2.85e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (7.51e-2)" "unprognostic (6.06e-3)" "unprognostic (3.14e-2)" "unprognostic (1.08e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (2.08e-2)" "unprognostic (4.14e-2)" "unprognostic (2.44e-2)" "unprognostic (6.41e-2)" 45.6 21.4 4.7 79.5 7.6 211.6 21.5 7.8 6.3 60.9 4.0 52.7 43.6 143.6 7.0 15.1 48.9 33.2 30.4 4.8 6.0 28.0 19.9 80.2 58.2 9.6 7.4 14.6 31.4 6.1 7.5 32.7 8.4 17.0 29.7 0.4 22.1 10.4 29.5 14.9 51.0 75.3 6.6 145.0 40.5 3.4 9.0 32.5 21.3 13.5 32.0 42.2 29.3 12.1 118.1 81.9 0.8 77.2 33.3 54.1 12.2 79.6 127.0 56.0 61.0 23.5 115.9 13.5 78.5 103.1 79.6 27.2 21.0 38.8 25.0 73.4 23.7 26.4 113.0 10.4 41.0 57.4 117.3 23.9 1.0 57.1 19.4 18.2 5.6 22.7 35.0 101.9 61.9 26.6 3.7 76.3 2.3 92.7 100.4 7.8 33.7 61.8 18.7 10.4 1.0 2.8 45.4 64.1 57.9 1.8 16.7 52.3 14.0 19.0 31.1 79.5 133.2 0.2 0.4 1.1 67.6 100.4 72.0 371.6 158.5 772.8 187.5 281.4 123.9 28.5 94.2 129.6 102.6 18.5 65.5 91.9 623.2 179.2 352.9 48.4 70.6 242.4 4.7 7.6 7.8 6.3 4.8 6.0 9.6 7.4 8.4 6.6 9.0 12.1 10.0 35.3 93.1 1.3 88.6 0.0 8.5 0.0 2.2 0.5 7.2 6.7 3.7 12.8 17.3 0.0 0.0 4.1 245.4 25.8 0.0 18.1 0.1 16.1 26.9 13.1 4.9 25.7 1.4 22.5 46.3 20.0 49.5 13.3 77.0 1.4 23.9 2.9 50.8 0.0 1.8 25.9 0.0 111.1 0.0 1.4 6.5 131.6 0.0 6.5 55.3 2.6 160.6 2.0 11.2 21.2 30.6 4.9 141.5 12.8 17.8 0.9 27.7 1.5 26.3 34.6 23.1 0.5 5.3 3.2 0.0 7.9 184.3 3.7 29.1 17.6 ADGRF1 "GPR110, hGPCR36, PGR19" ENSG00000153292 "Adhesion G protein-coupled receptor F1" Q5T601 6 46997708-47042350 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 17.5;kidney: 20.3;urinary bladder: 42.6" "Group enriched" "Detected in some" 4 "Collecting duct cells: 108.5;Pancreatic endocrine cells: 98.9;Urothelial cells: 363.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 31.2;CAPAN-2: 113.3;HaCaT: 25.3;PC-3: 36.6;RPTEC TERT1: 50.9;RT4: 132.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA038438 Approved "Secreted - unknown location" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "HPA038438: AB_10672645" "unprognostic (4.83e-4)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (6.71e-3)" "unprognostic (1.95e-3)" "unprognostic (3.02e-3)" "unprognostic (7.76e-2)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.20e-2)" "unprognostic (3.64e-3)" "unprognostic (1.99e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.41e-2)" "unprognostic (8.39e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 3.4 0.0 0.3 0.0 0.2 0.1 17.5 0.8 6.1 0.0 0.0 0.0 20.3 0.0 3.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 3.0 0.1 0.0 3.2 1.7 0.0 0.0 3.2 0.0 0.0 0.0 1.4 0.6 0.0 0.1 6.2 0.0 5.9 42.6 6.4 0.0 31.2 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 113.3 0.0 2.0 0.0 0.0 25.3 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 20.5 36.6 0.0 0.0 0.0 50.9 132.6 0.0 0.0 0.0 4.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 21.8 0.0 0.1 0.0 25.4 0.0 0.6 0.0 5.5 1.9 0.7 12.8 13.6 108.5 0.0 0.0 0.0 1.5 23.5 30.8 0.0 7.0 5.0 0.7 0.0 0.0 0.1 18.9 0.1 0.8 3.6 46.9 1.3 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.9 0.0 0.0 0.0 39.1 1.2 0.7 14.6 0.0 0.0 0.2 1.1 0.0 0.2 2.6 0.0 0.1 1.0 0.1 0.2 363.7 ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 216.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 222.5;Exocrine glandular cells: 170.7;NK-cells: 208.1;Syncytiotrophoblasts: 186.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.3" "Lineage enriched" "Detected in many" 5 "T-cells: 160.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 218.4;SK-BR-3: 277.7;SK-MEL-30: 297.8;TIME: 241.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" NA NA 32000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" 50.9 13.2 79.6 12.7 67.7 19.6 50.5 46.9 115.2 36.3 0.0 36.7 26.1 19.7 84.2 46.7 52.2 69.6 36.8 68.7 71.5 158.9 4.2 37.3 5.2 64.6 76.2 5.3 59.8 28.4 17.7 101.3 73.9 31.7 33.4 6.6 92.2 57.5 15.7 87.5 19.3 19.8 54.8 12.3 47.9 45.4 92.5 28.9 216.3 16.9 15.6 37.1 37.8 51.6 41.8 47.1 12.0 0.6 0.0 0.1 127.7 8.5 3.9 14.4 2.6 34.7 218.4 0.2 110.5 8.2 196.1 149.1 0.0 103.4 5.1 1.6 0.0 5.1 56.0 39.3 0.3 0.4 2.1 2.4 143.8 24.5 10.2 15.8 118.1 1.0 0.1 1.2 3.2 51.4 107.3 0.8 1.7 143.3 42.6 3.8 1.4 30.8 209.4 134.9 38.2 1.2 2.0 277.7 297.8 8.4 123.8 0.8 241.4 25.6 38.0 1.5 96.2 0.2 2.1 0.6 200.5 0.7 62.9 2.9 0.8 0.2 160.3 0.5 1.9 0.3 10.5 62.6 0.2 0.1 5.3 45.2 3.3 30.6 0.7 0.3 0.2 37.1 79.6 67.7 46.9 115.2 68.7 71.5 64.6 76.2 73.9 54.8 92.5 51.6 107.7 9.6 11.9 113.9 3.7 0.0 24.1 0.0 11.4 0.9 29.6 27.2 4.3 15.7 21.7 79.1 0.0 222.5 120.4 17.7 27.4 33.9 74.0 24.6 4.3 53.9 20.6 17.7 3.5 170.7 25.1 4.7 29.0 45.2 5.1 88.2 30.0 0.5 22.8 0.0 4.9 23.2 0.0 3.5 0.0 31.3 3.1 6.1 0.0 41.2 1.1 4.8 208.1 85.5 1.3 101.1 12.3 0.0 19.1 15.2 5.6 132.6 16.8 0.5 0.0 1.6 7.1 2.7 0.9 23.0 0.0 186.5 35.1 0.4 24.6 19.5 ADGRG5 "GPR114, PGR27" ENSG00000159618 "Adhesion G protein-coupled receptor G5" Q8IZF4 16 57542643-57591681 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 3.9;lymphoid tissue: 10.5" "Cell type enhanced" "Detected in some" "dendritic cells: 32.0;Microglial cells: 11.2;NK-cells: 43.3;Plasma cells: 16.4;T-cells: 7.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 125.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 39.4;OE19: 13.2;RPMI-8226: 6.2;THP-1: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA007133 Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear membrane, Vesicles" Nucleoplasm "HPA007133: AB_1849253" "unprognostic (6.11e-3)" "prognostic favorable (4.25e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (6.14e-2)" "unprognostic (1.14e-2)" "unprognostic (6.43e-2)" "unprognostic (1.42e-2)" "unprognostic (8.09e-4)" "unprognostic (3.80e-3)" "unprognostic (3.02e-3)" "unprognostic (1.91e-1)" "unprognostic (4.37e-3)" "unprognostic (7.69e-3)" "unprognostic (4.52e-1)" "unprognostic (1.62e-3)" "unprognostic (6.32e-3)" 0.3 0.3 0.3 5.0 0.2 1.4 0.7 0.2 0.2 0.2 0.1 1.7 3.7 0.3 0.1 0.6 0.5 0.1 0.0 0.3 0.4 0.0 0.2 0.9 10.5 0.8 0.4 0.0 0.0 0.1 0.2 0.0 0.6 0.3 1.3 0.0 1.3 0.3 0.1 0.1 3.9 0.3 0.6 5.8 0.4 0.4 0.4 1.6 0.3 0.0 10.5 1.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.4 39.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 3.6 3.6 13.2 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.2 0.1 125.9 33.3 0.1 16.9 12.0 4.8 19.1 2.4 8.6 1.2 11.2 0.5 29.9 0.1 68.8 0.2 9.0 0.3 0.2 0.2 0.2 0.3 0.4 0.8 0.4 0.6 0.6 0.4 0.3 0.3 0.0 1.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.8 0.0 0.0 0.0 0.0 0.2 32.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.3 0.0 0.6 0.0 0.3 0.0 3.2 0.0 11.2 1.7 0.0 43.3 0.0 0.3 0.0 0.0 0.0 16.4 0.1 2.9 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 7.1 0.0 0.7 0.0 ADGRG6 "FLJ14937, GPR126" ENSG00000112414 "Adhesion G protein-coupled receptor G6" Q86SQ4 6 142301854-142446266 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 71.9;placenta: 47.4" "Cell type enhanced" "Detected in many" "Endothelial cells: 41.7;Hepatocytes: 143.8;Kupffer cells: 40.5;Pancreatic endocrine cells: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 88.6;Hep G2: 84.8;hTERT-HME1: 81.5;HUVEC TERT2: 161.4;MCF7: 155.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017346 Approved NA NA 110000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA017346: AB_1849260" "unprognostic (1.04e-2)" "unprognostic (2.72e-2)" "unprognostic (7.37e-2)" "unprognostic (3.00e-2)" "unprognostic (8.64e-4)" "unprognostic (1.67e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.46e-1)" "unprognostic (6.49e-2)" "unprognostic (2.15e-1)" "unprognostic (1.36e-2)" "unprognostic (2.97e-2)" "unprognostic (4.59e-2)" 5.8 2.8 2.6 4.1 2.3 0.4 5.2 1.6 1.9 3.0 1.9 6.2 17.5 1.1 1.3 11.6 5.2 8.3 4.0 1.8 1.7 7.2 71.9 15.2 1.7 2.4 2.9 1.4 3.2 1.3 0.3 47.4 2.2 3.2 6.4 0.1 9.0 6.5 0.5 14.5 10.2 2.2 2.5 7.5 12.3 2.1 4.6 4.6 1.6 1.2 4.0 15.1 5.6 1.9 17.0 88.6 1.9 9.4 0.5 0.0 0.2 23.1 4.3 17.2 10.7 71.3 51.0 0.0 20.3 13.4 4.9 41.3 2.6 22.1 28.3 0.0 6.8 3.6 14.5 84.8 16.7 14.6 0.0 0.1 34.9 0.4 81.5 10.0 161.4 0.4 0.6 0.1 6.9 155.6 0.3 0.0 0.7 6.2 20.0 0.0 7.7 17.7 9.0 37.9 0.1 0.1 6.8 30.8 14.5 14.1 16.7 0.3 5.6 0.1 7.6 7.7 11.5 0.0 0.1 0.0 0.1 0.1 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.3 1.6 1.9 1.8 1.7 2.4 2.9 2.2 2.5 4.6 1.9 5.1 6.4 5.9 0.0 0.3 0.0 21.9 0.0 18.8 0.0 5.3 2.7 1.9 24.3 8.1 9.2 0.0 5.3 0.0 0.6 0.0 13.2 0.1 0.1 0.5 41.7 0.0 17.0 1.6 5.4 33.5 14.5 32.1 0.5 0.0 0.0 27.1 143.8 2.2 0.0 12.7 3.5 0.0 40.5 0.0 0.6 0.6 8.1 0.0 15.0 0.9 0.0 0.0 0.5 0.3 37.9 8.8 0.4 0.1 18.7 9.5 11.8 2.9 0.0 6.6 0.4 1.3 2.6 5.3 30.2 0.0 13.5 1.6 0.0 1.7 25.0 ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "adrenal gland: 533.0" "Cell type enriched" "Detected in many" 8 "Astrocytes: 2207.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 15.5;HAP1: 23.0;K-562: 9.8;NTERA-2: 11.6;SCLC-21H: 11.1;SuSa: 15.0;U-266/70: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067503 Approved Approved "Lipid droplets" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Lipid droplets" "HPA067503: AB_2685856" "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (2.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-3)" "unprognostic (1.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.95e-3)" "unprognostic (7.50e-3)" "unprognostic (9.73e-7)" "unprognostic (1.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.48e-2)" "unprognostic (7.14e-2)" 0.0 533.0 36.9 0.0 47.8 0.6 3.6 12.7 40.3 0.9 22.4 1.0 0.3 0.1 0.7 2.4 0.2 12.3 0.2 39.1 11.6 21.5 42.3 2.1 0.0 9.4 12.8 0.2 1.5 0.8 15.1 4.1 9.4 1.3 1.0 18.2 2.3 0.2 0.2 2.1 0.5 0.0 7.3 0.3 1.1 1.4 18.3 0.8 17.5 0.0 0.4 10.4 1.9 26.1 0.5 2.1 15.5 0.0 0.0 0.1 0.2 0.3 0.1 0.0 0.0 1.7 0.2 0.3 0.4 0.0 0.4 0.2 23.0 0.2 0.0 1.0 4.3 4.1 2.0 1.4 0.0 0.3 0.1 0.0 4.8 0.0 0.1 0.1 0.0 0.1 9.8 2.6 0.0 2.1 0.1 0.2 11.6 2.9 4.2 0.0 0.4 2.1 0.0 0.5 11.1 2.7 3.4 2.2 0.2 15.0 5.9 0.0 0.8 0.4 1.9 0.5 1.1 13.4 4.1 0.6 0.7 0.2 0.0 3.2 0.9 2.8 1.0 0.7 1.7 1.5 1.1 1.4 0.5 2.9 1.7 0.9 4.6 1.1 0.5 1.2 1.6 0.2 36.9 47.8 12.7 40.3 39.1 11.6 9.4 12.8 9.4 7.3 18.3 26.1 0.4 25.6 26.5 2207.3 0.0 0.0 6.1 0.0 1.8 28.0 15.5 7.4 2.4 2.8 5.6 5.5 264.8 3.0 0.4 0.6 1.9 1.9 43.5 3.3 0.3 1.1 7.3 0.0 54.0 4.2 2.6 1.1 4.6 1.9 0.0 6.7 0.0 12.4 0.2 10.1 21.9 0.4 0.0 0.8 0.0 54.8 0.6 0.5 0.0 51.5 1.2 8.9 1.0 40.2 7.4 1.7 1.2 0.4 0.1 2.1 0.1 24.2 7.3 84.4 0.0 0.3 0.4 3.6 4.5 2.9 0.0 4.1 0.6 0.2 1.2 9.0 ADI1 "APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL" ENSG00000182551 "Acireductone dioxygenase 1" Q9BV57 2 3497366-3519531 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 590.7" "Cell type enhanced" "Detected in all" "Distal tubular cells: 888.3;Hepatocytes: 1234.6;Proximal tubular cells: 1546.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035403, HPA035404" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus" "HPA035403: AB_10603576, HPA035404: AB_2674611" "unprognostic (2.19e-2)" "unprognostic (1.68e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "unprognostic (3.65e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-3)" "unprognostic (4.23e-3)" "unprognostic (2.36e-3)" "unprognostic (4.00e-3)" "unprognostic (2.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.90e-2)" "unprognostic (1.56e-1)" "unprognostic (9.94e-2)" "unprognostic (6.76e-2)" "unprognostic (8.74e-2)" 55.1 76.9 31.1 28.0 32.6 31.7 50.4 31.7 42.1 54.2 43.3 58.3 105.2 45.6 43.3 48.2 45.2 66.7 146.4 32.0 31.0 200.2 590.7 44.6 30.1 33.0 32.2 50.0 34.9 49.6 33.5 41.3 33.6 101.1 52.3 17.1 53.6 55.9 121.1 35.7 68.9 37.9 31.6 57.2 82.4 16.7 31.6 26.9 36.5 56.0 34.5 57.9 36.5 34.7 46.5 64.5 55.9 50.2 187.5 85.0 91.9 95.6 124.1 102.7 74.5 86.9 59.2 22.1 143.4 109.5 21.4 45.1 62.9 49.0 59.2 39.5 131.4 67.6 42.2 184.1 165.4 71.2 151.3 91.4 72.3 55.0 63.7 45.3 75.8 36.1 51.8 45.3 87.4 137.8 25.6 147.1 44.4 131.9 86.4 27.1 31.3 128.2 90.2 83.3 57.0 54.0 53.0 75.0 37.2 36.8 55.6 95.5 54.1 75.9 29.0 35.9 56.6 35.4 91.6 88.7 58.6 115.5 41.0 87.6 134.3 336.9 28.5 126.5 31.8 66.8 67.4 26.7 127.7 53.4 79.3 25.6 59.4 54.5 117.4 186.3 67.4 189.0 31.1 32.6 31.7 42.1 32.0 31.0 33.0 32.2 33.6 31.6 31.6 34.7 44.8 67.3 111.1 25.1 73.1 76.0 154.5 107.8 92.2 9.2 103.0 88.9 275.8 338.8 109.5 152.6 14.6 395.0 80.6 140.1 888.3 157.2 8.8 65.9 116.3 61.6 57.2 123.1 9.4 87.2 247.1 129.1 66.3 116.3 41.8 75.1 207.8 1234.6 263.2 8.4 15.0 146.1 236.0 168.8 67.6 23.8 137.0 90.0 204.5 7.5 108.2 197.2 40.2 5.5 19.0 79.7 272.5 210.3 97.4 143.6 409.8 1546.8 38.0 15.3 164.3 45.5 109.3 5.3 11.3 113.6 76.9 381.4 53.0 120.8 147.2 156.9 ADIG "MGC39724, RP5-1100H13.2, SMAF1" ENSG00000182035 Adipogenin Q0VDE8 20 38581195-38588463 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "testis: 53.5" "Cell type enriched" "Detected in some" 4 "Late spermatids: 1714.0" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041124 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA041124: AB_10795534" "unprognostic (2.97e-2)" "unprognostic (7.69e-3)" "unprognostic (2.27e-1)" "unprognostic (4.52e-3)" "unprognostic (1.34e-2)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 53.5 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 409.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1714.0 3.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 1.2 0.0 0.0 6.6 0.0 0.0 5.3 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADIPOQ "ACDC, ACRP30, adiponectin, apM1, GBP28" ENSG00000181092 "Adiponectin, C1Q and collagen domain containing" Q15848 3 186842704-186858463 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hormone "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 28 "adipose tissue: 898.8;breast: 248.9" "Cell type enhanced" "Detected in single" "Distal tubular cells: 1.9" "Group enriched" "Detected in some" 8 "breast cancer: 6.5;pancreatic cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 672 "ASC diff: 312.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB046467, HPA051767" Uncertain "Secreted to blood" NA NA 8360000000 910000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB046467: AB_1078104, HPA051767: AB_2681598" "unprognostic (1.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.20e-2)" "unprognostic (6.99e-3)" "unprognostic (1.87e-1)" 898.8 8.9 0.1 2.4 0.1 0.2 248.9 0.2 0.1 0.0 0.0 7.7 0.1 0.1 0.0 1.2 0.1 7.6 6.5 0.0 0.0 0.8 0.1 0.1 1.3 0.1 0.0 0.0 6.2 0.1 0.1 0.0 0.1 0.3 6.1 0.1 18.8 0.0 2.3 6.6 8.5 1.2 0.0 0.0 3.9 0.1 0.1 2.2 2.9 20.2 0.0 2.4 0.9 0.3 0.0 0.0 0.0 0.1 312.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADM AM ENSG00000148926 Adrenomedullin P35318 11 10305073-10307397 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 340.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 590.8;Extravillous trophoblasts: 1217.1;Syncytiotrophoblasts: 1084.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "neutrophil: 242.2" "Lineage enriched" "Detected in many" 18 "granulocytes: 242.2" "Cell line enhanced" "Detected in many" "ASC diff: 684.6;fHDF/TERT166: 357.4;HSkMC: 410.9;U-138 MG: 390.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016075, HPA068955" Approved "Secreted to blood" NA NA 31000 340000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB016075: AB_628693, HPA068955: " "unprognostic (1.67e-1)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (1.55e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.78e-3)" "unprognostic (1.06e-1)" "unprognostic (2.83e-1)" "unprognostic (8.13e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (6.33e-4)" "unprognostic (9.70e-3)" "unprognostic (2.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.62e-2)" 340.2 29.9 12.9 32.2 18.3 43.9 195.9 28.1 15.2 162.1 17.9 60.6 8.0 20.3 3.1 84.6 71.0 30.0 153.3 10.6 15.5 123.8 90.5 157.6 17.1 19.7 18.0 33.1 24.6 23.5 43.3 102.8 16.5 26.8 11.4 16.7 52.7 1.6 79.3 169.8 49.5 7.6 16.8 34.5 55.5 4.9 21.6 4.1 52.7 14.3 3.5 85.1 224.3 18.6 35.4 29.2 33.8 9.8 684.6 306.7 51.8 263.6 263.9 260.5 175.7 142.4 43.9 0.1 11.7 357.4 136.9 51.0 9.5 40.6 191.9 0.7 13.9 1.1 16.1 18.0 88.0 1.6 1.1 410.9 34.7 30.8 44.6 89.9 60.4 0.5 0.4 0.7 64.3 1.2 0.2 10.6 65.7 8.4 13.6 1.0 1.1 54.5 16.7 48.6 1.1 3.2 101.0 23.7 0.6 36.4 31.4 0.3 17.9 390.0 5.5 233.2 37.9 2.7 29.5 10.5 112.0 0.2 117.0 0.0 7.0 0.0 0.0 7.7 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.1 242.2 0.0 13.6 0.0 0.3 1.9 12.9 18.3 28.1 15.2 10.6 15.5 19.7 18.0 16.5 16.8 21.6 18.6 347.7 9.6 12.3 17.0 14.2 192.1 590.8 194.4 182.1 2.7 28.0 46.9 104.6 18.6 136.2 3.7 8.4 134.6 9.1 266.7 15.6 135.7 0.5 80.8 58.1 99.1 67.5 4.0 0.4 30.5 1217.1 202.8 55.0 210.9 9.5 30.1 95.7 18.6 71.4 3.3 3.0 127.6 181.0 69.6 57.7 2.6 132.7 107.9 40.9 6.5 8.1 4.9 1.0 1.5 0.1 61.7 298.3 19.2 20.0 218.9 14.0 60.1 38.7 15.3 0.0 73.3 76.5 5.1 4.9 182.3 125.6 1084.8 14.7 8.1 55.5 224.5 ADM2 "AM2, FLJ21135" ENSG00000128165 "Adrenomedullin 2" Q7Z4H4 22 50481543-50486440 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.3;pancreas: 15.5;thyroid gland: 11.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 10.0;Gastric mucus-secreting cells: 7.1;Intestinal goblet cells: 7.1;Pancreatic endocrine cells: 9.4;Proximal enterocytes: 7.4;Proximal tubular cells: 28.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 37.1;hTCEpi: 23.8;Karpas-707: 38.2;SK-MEL-30: 25.9;U-266/70: 25.6" "Not detected" "Not detected" "Secreted to blood" NA NA 61300 "Cluster 25: Pancreas - Digestion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.30e-2)" "unprognostic (4.96e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-1)" "unprognostic (3.15e-1)" "unprognostic (4.62e-3)" "unprognostic (7.26e-3)" "unprognostic (1.50e-1)" "unprognostic (3.44e-1)" "unprognostic (7.20e-2)" "unprognostic (9.41e-2)" "unprognostic (7.30e-3)" "unprognostic (1.17e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.06e-2)" 0.3 0.2 0.2 1.7 0.3 0.4 0.4 0.6 0.4 0.9 0.0 1.1 3.7 0.1 1.7 3.0 0.2 1.2 0.1 0.1 0.1 8.3 3.8 0.8 2.6 0.2 0.2 0.0 15.5 0.3 0.4 0.2 0.2 2.6 0.6 0.0 5.6 0.4 0.0 0.4 2.9 0.2 0.0 1.1 4.0 0.6 0.4 1.0 11.6 0.0 1.9 0.3 0.3 0.2 1.8 0.3 0.5 2.0 1.2 2.1 7.0 9.1 0.8 1.3 2.9 3.9 1.5 0.0 1.3 7.9 1.5 1.4 2.0 1.2 0.5 17.3 0.0 0.1 0.5 2.8 37.1 3.8 2.5 7.5 23.8 4.1 8.6 0.1 0.1 10.1 2.4 38.2 0.3 5.8 0.3 0.7 1.2 10.7 5.7 0.0 0.0 15.1 1.7 0.2 1.0 4.0 0.1 5.5 25.9 1.2 7.6 12.2 0.0 0.0 8.1 0.0 0.0 25.6 4.2 5.0 0.3 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.6 0.4 0.1 0.1 0.2 0.2 0.2 0.0 0.4 0.2 0.2 0.0 3.0 0.0 2.5 0.0 0.9 1.0 0.0 0.0 3.6 1.8 1.4 1.5 0.5 0.0 0.0 0.1 0.6 3.9 3.9 2.6 0.0 0.5 0.4 0.3 1.2 0.0 0.0 10.0 0.7 0.2 7.1 1.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 7.1 0.0 0.0 0.3 0.2 0.0 0.4 1.8 0.0 0.6 0.0 1.0 0.0 0.0 9.4 1.4 0.0 3.1 2.0 7.4 28.1 0.1 0.0 0.0 1.1 0.7 0.2 1.0 0.0 0.4 1.0 1.2 0.0 1.1 0.9 ADM5 "AM5, C19orf76" ENSG00000224420 "Adrenomedullin 5 (putative)" C9JUS6 19 49688664-49690575 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 29.3;Endothelial cells: 47.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 18.0" "Secreted to blood" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.34e-2)" "unprognostic (2.56e-1)" "unprognostic (3.08e-3)" "unprognostic (5.62e-2)" "unprognostic (2.18e-2)" "unprognostic (2.64e-2)" "unprognostic (1.28e-1)" "unprognostic (2.39e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (1.47e-2)" "unprognostic (8.94e-2)" "unprognostic (4.21e-11)" "unprognostic (2.39e-2)" "unprognostic (9.25e-2)" "unprognostic (9.92e-3)" "prognostic favorable (6.74e-4)" 7.8 0.8 1.9 0.7 1.9 1.3 6.0 4.5 2.9 3.7 1.5 2.4 0.8 4.3 0.3 3.3 5.0 0.6 1.8 2.0 1.9 3.5 1.8 4.3 1.0 1.9 1.9 2.0 1.8 0.1 2.7 0.7 2.2 3.9 0.2 1.5 2.6 0.4 3.9 5.0 2.9 0.8 1.8 6.7 2.3 3.0 2.2 0.7 2.6 0.4 0.7 3.6 3.6 1.9 3.4 5.7 3.3 2.3 0.1 0.0 3.9 0.3 0.3 1.1 0.6 6.6 3.1 5.1 1.2 0.2 0.3 1.0 5.9 1.9 0.4 6.0 11.3 5.8 1.6 4.3 0.1 1.7 3.8 0.6 4.2 0.7 0.5 0.8 1.1 5.4 4.2 3.7 0.2 5.4 2.6 18.0 4.4 0.6 1.6 7.4 2.5 5.3 0.5 5.9 2.0 0.9 0.8 1.6 1.6 0.8 3.6 2.5 0.9 1.8 6.6 0.9 1.4 12.6 10.7 5.9 1.2 10.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.9 4.5 2.9 2.0 1.9 1.9 1.9 2.2 1.8 2.2 1.9 29.3 0.0 1.5 1.3 1.4 6.1 1.4 1.4 6.2 4.3 5.4 6.1 0.1 1.5 1.5 0.0 0.0 0.5 1.0 1.8 0.0 0.5 8.1 3.0 1.9 47.3 1.2 0.0 0.3 1.1 0.5 2.2 1.5 6.0 0.0 0.7 5.0 0.3 0.3 0.0 0.4 1.5 0.0 1.0 4.9 4.3 0.6 1.3 5.4 0.0 0.2 0.9 0.0 0.0 0.9 0.6 0.4 0.7 0.2 1.9 0.3 0.0 1.6 2.4 0.0 2.9 1.5 1.1 1.2 6.2 6.3 0.1 1.3 0.3 1.6 1.1 ADPGK "ADP-GK, DKFZp434B195" ENSG00000159322 "ADP dependent glucokinase" Q9BRR6 15 72751369-72785846 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 140.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045194, HPA058525" Approved Approved Centrosome "Intracellular and membrane" NA NA 66000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 18: U-2197 - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Centrosome "HPA045194: AB_10964638, HPA058525: AB_2683742" "unprognostic (5.96e-3)" "unprognostic (1.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.82e-1)" "unprognostic (1.29e-1)" "unprognostic (1.98e-1)" "unprognostic (1.45e-1)" "unprognostic (8.50e-2)" "unprognostic (2.27e-1)" "unprognostic (1.09e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.22e-4)" "prognostic unfavorable (4.52e-7)" "unprognostic (1.92e-1)" "unprognostic (6.05e-2)" "unprognostic (1.60e-1)" "unprognostic (2.07e-2)" 10.1 7.5 2.7 15.3 2.8 23.7 8.7 3.3 3.8 7.3 9.7 10.3 8.0 5.4 12.1 7.5 9.5 7.0 5.3 2.9 4.9 11.7 10.8 17.0 13.5 4.4 4.4 5.9 7.8 6.6 3.8 16.5 5.0 12.1 11.8 4.3 9.6 5.3 4.7 7.1 8.6 7.8 3.8 13.6 9.8 7.2 3.9 15.3 9.2 5.3 16.4 13.7 5.9 4.9 18.5 37.8 19.8 23.5 43.8 33.2 26.6 52.7 51.0 54.0 74.4 21.5 47.6 34.7 38.3 33.1 53.6 49.0 56.6 27.7 40.2 34.5 38.8 26.0 9.9 20.3 28.2 60.3 37.3 36.2 15.7 28.6 26.4 26.4 31.8 26.7 27.7 57.6 33.1 11.6 18.8 27.0 29.6 36.7 17.6 21.9 32.3 48.5 27.9 21.3 14.3 14.7 48.2 19.7 26.3 30.8 18.9 71.9 26.4 27.0 22.4 103.2 48.5 57.8 119.3 34.6 47.2 58.4 45.7 56.8 69.2 51.6 22.4 48.4 27.9 30.4 20.6 22.8 72.5 26.7 17.7 20.2 27.2 32.0 41.5 55.4 17.9 59.6 2.7 2.8 3.3 3.8 2.9 4.9 4.4 4.4 5.0 3.8 3.9 4.9 19.3 19.2 34.3 22.5 61.7 15.3 20.9 22.7 17.1 15.6 20.1 14.7 3.9 8.6 23.8 20.2 14.6 38.2 75.6 15.1 7.9 25.8 14.9 18.2 22.6 20.2 7.8 10.5 13.0 17.4 62.0 27.4 23.4 17.5 48.9 31.6 21.4 23.9 80.4 15.2 17.5 17.0 24.4 101.3 51.6 6.4 21.8 68.5 26.6 31.9 140.6 11.7 42.2 13.0 22.1 22.3 16.9 15.4 34.9 34.4 15.6 10.7 24.8 24.4 19.7 19.2 16.4 24.4 31.3 11.8 18.2 41.7 36.0 22.9 20.9 31.2 ADPRS "ADPRHL2, ARH3, FLJ20446" ENSG00000116863 "ADP-ribosylserine hydrolase" Q9NX46 1 36088892-36093932 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 79.2;Extravillous trophoblasts: 40.7;Hofbauer cells: 51.6;Syncytiotrophoblasts: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026641, HPA027104, HPA027141" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA 54000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA026641: , HPA027104: AB_10601330, HPA027141: AB_1844619" "unprognostic (3.22e-3)" "unprognostic (5.10e-2)" "unprognostic (2.95e-2)" "unprognostic (1.61e-2)" "unprognostic (5.98e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.10e-7)" "unprognostic (3.71e-2)" "unprognostic (2.63e-1)" "unprognostic (5.34e-2)" "unprognostic (3.17e-2)" "unprognostic (7.80e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (9.31e-2)" "unprognostic (3.65e-2)" "unprognostic (4.74e-2)" 19.0 36.7 28.4 16.0 30.0 19.7 18.5 31.3 30.3 20.7 33.4 19.6 15.6 17.6 15.0 36.1 33.5 13.3 20.7 28.6 29.1 27.7 22.4 20.6 21.5 32.5 29.7 19.7 17.9 17.6 17.7 20.8 31.2 19.9 12.4 9.1 20.9 16.3 34.4 34.1 16.8 16.4 31.9 23.1 17.6 28.7 29.7 20.9 19.4 21.8 20.2 21.3 22.2 33.9 54.3 22.4 26.2 37.2 23.6 17.1 37.3 39.4 32.9 62.1 60.9 26.8 47.7 38.4 37.5 39.5 32.0 32.9 33.4 60.5 37.0 27.7 41.8 34.9 27.0 36.3 44.4 40.2 19.9 20.3 45.4 56.5 24.5 47.2 39.9 36.2 30.8 30.9 29.6 26.0 40.9 60.5 56.5 31.8 46.0 32.9 27.6 38.8 56.5 43.8 32.1 50.8 28.9 29.9 65.9 34.4 30.9 34.3 27.6 35.7 37.0 50.1 53.0 39.8 41.2 34.2 51.7 39.6 22.4 40.6 58.3 65.8 43.4 74.1 41.5 43.5 47.6 50.8 71.4 51.5 47.7 40.3 57.1 47.9 77.7 44.8 43.4 57.8 28.4 30.0 31.3 30.3 28.6 29.1 32.5 29.7 31.2 31.9 29.7 33.9 3.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 79.2 6.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 40.7 6.4 0.0 0.0 0.0 0.0 0.0 0.0 51.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 70.6 1.3 0.0 0.0 0.0 ADSS1 "ADSSL1, FLJ38602" ENSG00000185100 "Adenylosuccinate synthase 1" Q8N142 14 104724229-104747325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "skeletal muscle: 1273.1;tongue: 609.8" "Cell type enriched" "Detected in some" 20 "Cardiomyocytes: 137.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 15.2;MCF7: 14.2;OE19: 23.2;SiHa: 23.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052621 Enhanced NA NA 290000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA052621: " "unprognostic (2.23e-2)" "unprognostic (3.15e-1)" "unprognostic (1.72e-3)" "unprognostic (5.14e-2)" "unprognostic (2.81e-3)" "unprognostic (3.46e-1)" "unprognostic (1.70e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (2.26e-1)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.99e-4)" "unprognostic (2.33e-1)" "unprognostic (2.35e-1)" "unprognostic (2.18e-2)" "unprognostic (2.78e-2)" 8.1 5.1 3.8 1.0 6.8 0.9 4.4 6.6 5.6 4.1 7.6 3.0 2.7 3.3 4.5 18.5 6.5 5.7 100.2 3.7 6.7 14.8 28.8 3.1 1.1 6.0 6.0 2.7 7.9 7.3 10.0 7.3 6.1 7.6 1.4 10.1 10.7 4.0 1273.1 5.5 2.8 2.3 5.2 2.0 6.5 18.5 5.5 1.0 7.4 609.8 0.8 6.5 5.4 7.7 0.1 3.2 2.4 7.1 1.7 1.1 0.8 0.9 1.3 0.2 0.7 0.2 2.5 0.0 15.2 0.8 0.5 1.3 0.2 0.5 0.6 1.0 0.5 0.1 7.9 1.1 1.8 0.0 6.0 3.2 2.3 0.0 2.6 2.7 0.4 0.3 2.9 0.1 1.2 14.2 0.0 0.7 2.1 23.2 1.3 0.2 0.3 0.9 0.5 1.7 2.0 4.2 23.1 1.0 3.3 1.8 7.1 2.1 0.8 0.1 0.6 1.6 0.1 4.4 3.5 0.0 2.2 1.0 1.5 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.8 6.8 6.6 5.6 3.7 6.7 6.0 6.0 6.1 5.2 5.5 7.7 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 137.4 0.0 0.0 0.0 0.0 3.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.7 6.6 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104345-44114562 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 103.0;Fibroblasts: 263.2;Leydig cells: 151.6;Peritubular cells: 508.9;Smooth muscle cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.6" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.6" "Cell line enhanced" "Detected in many" "ASC diff: 141.1;BJ: 193.0;BJ hTERT+: 126.0;fHDF/TERT166: 208.9;JURKAT: 145.0;WM-115: 117.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 57.6" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2700000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB009966: AB_2225690, HPA047724: AB_2680132, HPA063595: AB_2685052, HPA064970: AB_2685394" "unprognostic (1.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.13e-1)" "unprognostic (7.00e-2)" "unprognostic (8.79e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.31e-9)" "unprognostic (2.88e-3)" "unprognostic (9.58e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-3)" 190.5 59.9 45.0 59.8 56.0 10.6 153.0 38.6 44.8 312.1 28.0 95.3 19.2 268.8 59.6 65.7 199.8 155.9 156.7 47.3 92.9 68.7 20.3 166.0 45.5 114.7 81.5 253.7 28.9 10.1 43.3 89.0 79.6 112.1 25.0 1.3 50.7 213.5 21.3 84.8 79.1 119.3 74.3 54.4 71.2 40.4 52.1 73.3 83.7 14.1 16.7 138.7 198.0 66.6 0.6 0.0 44.5 0.1 141.1 49.6 1.0 193.0 126.0 21.6 4.5 0.0 0.1 5.3 20.9 208.9 0.2 0.1 2.4 3.5 9.1 0.6 0.0 13.3 0.1 0.0 39.6 0.1 0.3 75.8 0.0 72.9 0.1 1.1 9.7 145.0 8.3 0.3 0.0 0.2 86.9 16.1 19.1 0.0 0.4 71.3 1.7 1.7 5.0 0.0 4.9 25.3 0.1 0.3 85.9 41.9 0.4 14.4 34.1 0.0 86.2 0.5 0.3 1.0 0.9 102.8 0.4 0.2 117.9 0.0 0.0 0.0 0.3 0.0 0.2 1.5 0.2 0.0 0.0 1.4 0.9 0.5 0.0 0.1 0.0 7.6 0.0 0.3 45.0 56.0 38.6 44.8 47.3 92.9 114.7 81.5 79.6 74.3 52.1 66.6 23.6 0.0 2.5 32.3 11.8 34.5 5.7 1.3 1.8 0.8 2.0 14.6 26.4 1.5 1.4 7.3 0.0 2.0 22.7 0.0 0.0 0.9 3.1 3.3 103.0 18.0 0.0 1.3 0.1 0.0 3.3 263.2 8.6 2.9 2.5 33.3 30.4 0.6 3.6 0.0 0.3 0.0 0.0 1.8 42.0 18.0 151.6 3.2 85.4 17.8 1.0 0.2 1.0 6.0 0.3 0.4 0.0 508.9 9.7 16.9 0.0 2.2 2.2 0.8 39.5 23.6 173.4 4.0 4.6 1.5 27.4 3.4 4.8 28.7 0.0 2.4 AFG1L "AFG1, LACE1" ENSG00000135537 "AFG1 like ATPase" Q8WV93 6 108294991-108526796 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 6.4;Distal tubular cells: 9.8;Hofbauer cells: 5.7;Proximal tubular cells: 6.3;Respiratory ciliated cells: 5.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030154, HPA030155, HPA030659" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA030154: AB_10600769, HPA030155: AB_10601232, HPA030659: AB_10602415" "unprognostic (9.76e-5)" "unprognostic (1.72e-1)" "unprognostic (1.68e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-1)" "unprognostic (7.04e-2)" "unprognostic (2.57e-1)" "unprognostic (5.53e-2)" "unprognostic (2.35e-3)" "unprognostic (1.48e-1)" "unprognostic (2.73e-2)" "unprognostic (9.61e-2)" "unprognostic (8.40e-8)" "unprognostic (2.03e-2)" "unprognostic (2.03e-1)" "unprognostic (1.41e-1)" "unprognostic (1.23e-1)" 1.8 2.1 2.2 1.3 2.7 2.1 2.2 2.0 3.3 1.7 2.7 2.6 4.2 1.5 1.9 1.6 2.2 1.5 4.6 1.7 1.9 5.0 3.7 1.7 1.8 1.8 2.0 1.7 2.1 5.4 1.5 2.2 2.0 1.6 3.1 3.1 1.8 1.7 3.7 1.2 3.0 1.7 1.7 2.0 2.8 10.7 2.7 2.3 3.0 4.0 2.1 1.7 1.1 3.2 2.7 1.4 3.4 6.1 3.5 5.1 3.3 3.0 4.4 4.8 4.7 5.7 3.3 4.8 3.8 4.7 5.8 1.5 4.4 4.5 5.4 2.8 2.6 5.7 1.8 6.6 3.5 5.3 2.7 4.7 3.6 3.6 5.8 3.1 2.6 3.5 5.9 2.2 4.5 2.6 0.9 4.8 2.2 4.6 2.8 3.3 4.6 2.8 6.1 2.9 3.7 3.2 2.4 3.5 6.4 4.5 2.8 9.8 3.2 2.9 0.7 2.6 3.4 1.5 2.6 3.7 3.6 6.0 4.5 0.0 1.6 2.8 1.0 1.2 1.3 2.5 1.5 1.9 1.4 3.4 2.1 1.4 0.4 2.4 4.3 1.6 2.3 0.7 2.2 2.7 2.0 3.3 1.7 1.9 1.8 2.0 2.0 1.7 2.7 3.2 2.4 0.0 4.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 2.2 0.0 0.0 5.0 3.7 0.0 6.4 1.1 0.0 9.8 3.1 0.0 2.6 2.6 2.2 0.0 0.0 0.0 3.8 4.6 1.2 0.0 1.8 2.5 5.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.4 0.0 0.0 6.3 5.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.2 0.9 4.5 0.0 0.0 AFM "ALB2, ALBA" ENSG00000079557 Afamin P43652 4 73481745-73504001 "Plasma proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 961.6" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 300.4" "Cancer enriched" "Detected in single" 167 "liver cancer: 62.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "CACO-2: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017006, HPA052437" Enhanced "Secreted to blood" NA NA 54900000000 8700000000 "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "HPA017006: AB_1844635, HPA052437: AB_2732575" "prognostic favorable (1.80e-4)" "unprognostic (5.73e-2)" "unprognostic (4.24e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 79.7 961.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.0 0.0 0.0 0.0 0.3 0.2 4.3 0.0 1.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 4.2 300.4 0.1 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 42.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.0 0.0 AFP "FETA, HPAFP" ENSG00000081051 "Alpha fetoprotein" P02771 4 73431138-73456174 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "liver: 3.7" "Group enriched" "Detected in some" 10 "Hepatocytes: 107.5;Proximal tubular cells: 101.6" "Cancer enriched" "Detected in some" 4 "liver cancer: 208.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 192 "Hep G2: 2165.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010607, HPA023600, CAB024283, CAB025339" Approved Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 3010000 150000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Cytosol "CAB024283: AB_2650473, CAB025339: , HPA010607: AB_1078141, HPA023600: AB_1844769" "unprognostic (4.69e-1)" "unprognostic (1.87e-1)" "unprognostic (3.34e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-3)" "unprognostic (2.95e-2)" "unprognostic (3.35e-1)" "unprognostic (1.54e-1)" "unprognostic (3.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.63e-6)" "unprognostic (1.98e-2)" "unprognostic (5.80e-2)" "unprognostic (1.14e-1)" 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2165.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 1.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 9.7 5.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 7.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 2.7 2.8 0.3 0.0 0.1 0.0 0.1 2.5 107.5 2.3 0.0 0.1 0.1 0.0 3.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 101.6 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 1.5 0.2 0.1 0.2 0.0 AGA ASRG ENSG00000038002 Aspartylglucosaminidase P20933 4 177430774-177442437 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 77.5;Karpas-707: 111.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031415, HPA031417" Enhanced "Intracellular and membrane" NA NA 36000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA031415: AB_10603578, HPA031417: AB_10670967" "unprognostic (8.76e-2)" "unprognostic (1.56e-1)" "unprognostic (2.22e-3)" "unprognostic (2.11e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (8.61e-4)" "prognostic unfavorable (1.99e-4)" "unprognostic (3.79e-1)" "unprognostic (6.44e-2)" "unprognostic (4.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.09e-1)" "unprognostic (7.49e-2)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (7.42e-2)" "unprognostic (1.47e-2)" 9.4 13.3 8.1 9.1 10.4 15.4 21.1 9.8 12.0 9.2 16.2 13.1 9.6 8.6 30.2 15.9 8.4 13.1 7.5 8.4 9.9 15.3 18.7 11.6 12.2 11.4 9.1 10.2 15.1 17.1 6.1 8.4 11.4 11.8 13.1 6.6 14.9 9.8 9.0 20.6 12.4 9.5 9.5 10.3 16.2 13.2 8.6 11.1 15.8 5.8 15.6 10.9 8.2 13.7 5.4 11.9 13.3 18.8 14.9 13.2 9.0 39.5 77.5 20.1 24.8 6.2 26.2 26.9 7.2 30.0 9.7 6.5 11.3 13.0 39.4 17.3 7.5 11.2 11.9 17.3 10.0 19.6 7.4 9.6 22.5 14.7 6.5 18.0 18.7 11.4 10.3 111.6 8.0 14.6 15.9 12.0 5.2 10.5 12.2 5.0 5.4 4.0 20.5 12.9 7.3 16.4 11.9 10.3 32.2 9.9 23.3 39.8 6.1 13.9 12.3 6.6 15.2 21.2 17.4 14.0 22.3 22.0 16.0 26.4 15.3 23.9 15.6 27.5 17.9 13.9 16.6 18.8 14.8 12.9 14.8 21.3 3.3 12.7 35.8 15.8 17.8 15.1 8.1 10.4 9.8 12.0 8.4 9.9 11.4 9.1 11.4 9.5 8.6 13.7 12.6 12.8 13.5 2.6 20.5 24.0 17.4 26.9 12.5 3.9 19.8 16.9 7.5 15.7 21.7 14.7 2.1 26.3 17.6 8.4 5.9 28.2 13.6 8.9 8.5 10.9 5.4 7.8 3.7 31.3 32.0 16.0 13.7 12.5 14.0 13.9 8.2 23.5 23.1 6.7 2.3 18.2 14.2 15.4 23.3 9.2 11.1 15.9 39.2 2.8 23.8 19.1 11.3 3.5 19.3 21.4 9.1 9.8 48.8 13.4 15.1 22.1 10.5 4.8 0.0 8.4 14.1 35.8 36.6 23.7 27.3 22.7 22.5 14.1 13.6 17.7 AGER "RAGE, SCARJ1" ENSG00000204305 "Advanced glycosylation end-product specific receptor" Q15109 6 32180968-32184322 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lung: 728.3" "Cell type enriched" "Detected in many" 22 "Alveolar cells type 1: 2394.2" "Cancer enhanced" "Detected in all" "lung cancer: 27.2;thyroid cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.5;JURKAT: 3.0;RPTEC TERT1: 2.2;U-266/70: 2.4;U-266/84: 2.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB011682, HPA064436, HPA069474" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cell Junctions" "Secreted in other tissues" NA NA 5360000 100000 "Cluster 19: Lung - Lung function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cell Junctions" "Nucleoli fibrillar center" "CAB011682: AB_2258049, HPA064436: AB_2685264, HPA069474: " "unprognostic (9.37e-2)" "unprognostic (3.70e-1)" "unprognostic (2.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.55e-2)" "unprognostic (1.59e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (4.38e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.01e-7)" "unprognostic (3.57e-1)" "unprognostic (3.70e-2)" "unprognostic (4.44e-2)" "prognostic favorable (2.74e-6)" 2.2 1.7 0.1 1.1 0.1 0.5 1.6 0.1 0.4 4.4 0.2 3.9 0.6 2.5 1.9 2.1 4.5 0.1 2.7 0.2 0.1 6.4 2.7 728.3 0.6 0.2 0.1 4.8 1.7 0.0 5.0 0.4 0.2 4.9 0.8 0.4 1.6 0.0 1.0 2.0 3.2 0.1 0.1 7.0 2.0 2.2 0.2 0.8 39.2 0.1 0.5 2.9 3.2 0.3 0.1 0.0 0.0 0.3 0.1 0.9 1.5 0.0 0.1 0.0 0.1 0.0 0.2 0.1 1.0 0.2 0.0 1.0 0.1 0.3 0.2 0.2 2.5 0.7 0.0 0.0 0.0 0.3 1.1 0.0 0.1 0.0 0.1 0.2 0.1 3.0 0.0 0.3 0.1 1.3 0.1 0.9 0.0 0.1 0.0 0.0 0.1 0.1 2.2 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.5 0.0 0.1 0.0 0.6 0.8 0.1 2.4 2.0 0.9 1.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.3 5.4 2394.2 107.9 5.9 4.9 0.9 1.5 2.0 2.8 5.1 1.5 2.9 3.0 4.3 20.9 1.8 0.0 1.1 2.7 1.1 0.0 1.5 0.4 1.1 2.6 4.1 0.0 4.4 0.5 1.0 0.9 3.0 1.5 1.9 17.7 3.1 2.9 2.0 1.3 6.7 0.6 1.3 0.0 5.3 6.5 1.2 1.8 5.3 1.8 4.7 4.8 4.6 2.1 2.5 1.3 1.1 2.7 1.2 3.3 2.6 0.8 0.3 5.6 3.4 6.6 1.2 2.6 0.1 1.2 1.6 1.8 2.2 6.2 1.7 1.2 0.9 AGK "FLJ10842, MULK" ENSG00000006530 "Acylglycerol kinase" Q53H12 7 141551278-141655244 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Cardiomyopathy, Cataract, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.4;Inhibitory neurons: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 97.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020959, HPA053471" Supported Supported Vesicles,Mitochondria "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria Vesicles "HPA020959: AB_1854206, HPA053471: AB_2682164" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.28e-2)" "unprognostic (9.47e-3)" "unprognostic (5.43e-2)" "unprognostic (2.15e-2)" "unprognostic (3.68e-2)" "unprognostic (2.03e-1)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (6.24e-3)" "unprognostic (7.90e-2)" "unprognostic (9.29e-2)" "unprognostic (9.65e-2)" "unprognostic (3.30e-1)" "unprognostic (1.18e-1)" 10.1 14.7 9.4 8.5 10.9 5.6 11.9 8.3 12.8 11.5 10.2 11.8 5.9 11.7 14.5 12.2 12.2 7.8 30.4 11.1 10.8 15.7 14.1 11.6 12.1 8.0 8.8 11.3 10.1 21.5 13.7 10.0 9.0 12.8 13.1 12.7 13.7 11.4 8.6 9.6 12.0 15.4 8.2 16.6 12.2 6.6 10.0 14.0 12.7 10.0 14.7 10.8 11.5 9.0 23.7 25.6 26.7 21.8 21.2 29.4 16.2 23.5 29.3 44.5 50.9 24.7 18.3 26.3 24.0 26.8 40.5 18.7 41.6 32.8 51.0 33.8 32.7 26.1 10.7 18.7 34.1 15.6 12.5 29.9 26.9 36.3 33.1 19.8 34.1 32.3 36.3 36.9 25.3 24.6 47.3 9.1 25.6 19.9 32.4 29.2 4.2 80.1 33.1 20.8 23.3 29.6 24.6 29.7 27.1 26.1 16.3 20.2 19.5 18.9 14.1 23.8 38.1 29.5 31.9 14.4 30.7 9.1 50.4 0.4 7.1 1.2 22.1 13.9 15.3 10.8 17.3 26.0 16.2 6.5 12.8 23.5 1.2 97.3 8.2 6.3 18.9 15.7 9.4 10.9 8.3 12.8 11.1 10.8 8.0 8.8 9.0 8.2 10.0 9.0 8.4 0.0 6.0 22.5 11.4 3.1 5.6 7.9 5.2 11.8 5.5 5.1 18.1 2.8 6.6 12.9 8.4 15.7 15.8 3.0 9.8 6.6 9.9 7.4 9.0 7.5 0.0 11.8 43.4 6.9 8.2 7.7 10.7 6.6 8.2 9.9 4.2 4.1 7.0 15.2 43.0 3.9 12.2 5.1 4.9 12.0 6.8 5.6 7.2 26.2 12.4 11.2 27.8 38.7 37.9 6.1 2.1 10.5 22.1 2.9 2.4 8.2 7.6 17.4 0.0 6.2 8.0 6.2 4.9 11.3 2.7 9.2 15.0 14.2 5.6 3.8 AGPS "ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY" ENSG00000018510 "Alkylglycerone phosphate synthase" O00116 2 177392746-177567024 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cataract, Disease variant, Dwarfism, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 262.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030209, HPA030210, HPA030211" Supported Supported Peroxisomes "Intracellular and membrane" NA NA 69000 "Cluster 26: Non-specific - Mitochondria" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Peroxisomes "HPA030209: AB_10600634, HPA030210: AB_10600202, HPA030211: AB_10602195" "unprognostic (7.10e-2)" "unprognostic (1.20e-2)" "unprognostic (1.76e-3)" "unprognostic (3.79e-2)" "unprognostic (8.34e-2)" "unprognostic (3.78e-2)" "prognostic unfavorable (8.62e-6)" "unprognostic (1.23e-2)" "unprognostic (7.23e-2)" "unprognostic (5.41e-2)" "prognostic unfavorable (8.35e-4)" "unprognostic (7.74e-2)" "prognostic favorable (9.45e-4)" "unprognostic (7.18e-2)" "unprognostic (3.46e-1)" "unprognostic (4.94e-3)" "unprognostic (1.92e-2)" 14.3 9.2 4.4 15.6 6.9 19.6 13.9 7.1 6.9 14.3 4.6 20.1 11.1 14.6 6.5 12.7 9.8 11.3 10.4 4.7 6.6 18.1 19.3 13.7 11.9 8.9 7.0 7.8 11.4 18.5 3.4 13.2 8.2 7.0 21.9 6.4 8.3 8.8 11.7 4.5 13.1 21.1 7.8 8.7 9.9 16.3 6.3 16.1 12.6 12.6 12.8 14.6 5.2 11.9 43.1 36.3 23.3 19.0 32.2 33.2 33.3 29.6 21.9 34.5 34.8 70.6 34.0 58.5 59.5 45.0 46.3 47.5 64.4 45.1 47.8 51.4 16.7 77.6 56.5 75.8 31.9 82.3 63.5 28.6 28.7 58.6 44.6 33.3 75.3 42.1 44.9 26.3 45.7 0.1 59.9 22.4 33.3 42.7 30.9 47.0 65.1 32.7 60.0 65.0 22.0 31.3 66.2 5.8 43.0 58.1 0.4 35.4 70.0 29.4 61.9 26.8 64.2 28.7 59.0 23.6 29.4 43.1 11.8 2.6 3.3 5.8 1.9 4.0 2.9 1.7 3.0 2.4 3.6 1.1 2.7 1.6 1.5 2.8 3.6 0.1 4.3 2.2 4.4 6.9 7.1 6.9 4.7 6.6 8.9 7.0 8.2 7.8 6.3 11.9 20.2 16.0 13.1 29.4 10.7 10.8 6.5 15.5 12.0 11.5 19.2 6.7 20.0 20.0 13.0 14.7 2.1 14.1 15.5 25.6 13.7 20.9 262.2 25.2 17.2 14.0 19.8 20.8 53.0 23.2 20.6 23.0 18.8 25.4 64.1 16.6 11.7 31.0 31.8 15.2 61.7 30.4 16.2 30.0 31.8 41.4 14.6 28.7 14.2 56.2 36.0 12.0 21.6 45.8 83.8 23.9 17.4 13.9 14.1 3.8 15.3 46.5 21.6 7.6 6.6 16.8 16.4 41.7 22.2 16.2 9.8 7.0 19.0 22.7 26.0 6.1 AGR2 "AG2, HAG-2, PDIA17, XAG-2" ENSG00000106541 "Anterior gradient 2, protein disulphide isomerase family member" O95994 7 16791811-16833433 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 638.7;intestine: 1224.0;stomach 1: 1402.3" "Cell type enhanced" "Detected in many" "Club cells: 1515.8;Distal enterocytes: 1026.4;Gastric mucus-secreting cells: 2605.5;Intestinal goblet cells: 3710.4;Paneth cells: 1101.6;Undifferentiated cells: 1543.1;Urothelial cells: 1017.8" "Cancer enhanced" "Detected in many" "stomach cancer: 475.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 15 "OE19: 20084.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007912 Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 38000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum" "HPA007912: AB_1844879" "unprognostic (6.19e-2)" "unprognostic (1.91e-1)" "unprognostic (9.05e-2)" "unprognostic (2.59e-2)" "unprognostic (2.23e-1)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.49e-2)" "unprognostic (1.84e-1)" "unprognostic (1.08e-2)" "unprognostic (3.24e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (8.79e-5)" "unprognostic (6.98e-2)" "unprognostic (2.38e-1)" "unprognostic (2.38e-1)" "unprognostic (3.22e-3)" 2.1 0.7 0.0 66.6 0.0 0.0 72.3 0.2 0.5 638.7 0.0 768.1 486.0 14.1 389.1 16.2 306.4 275.8 0.2 0.1 0.0 11.2 0.9 50.7 0.6 0.0 0.1 0.3 22.1 0.1 31.4 1.6 0.0 227.3 1224.0 0.0 475.3 181.0 0.2 2.5 379.2 45.2 0.0 0.9 1402.3 0.9 0.0 1.7 7.4 0.1 7.2 160.8 4.0 0.1 0.3 265.5 0.0 0.3 0.0 0.1 2.6 0.0 0.0 0.0 0.0 43.5 39.7 0.0 0.2 0.0 6.6 25.2 0.0 34.5 0.2 0.0 0.0 0.0 0.9 3.8 0.0 0.0 1.0 0.0 88.5 0.0 11.4 0.4 0.4 0.3 0.0 0.0 0.2 44.7 1.3 1.8 0.8 20084.0 154.2 1.0 0.0 5.2 631.3 371.6 1.7 2.1 0.0 98.8 0.0 1.0 1319.9 0.0 0.0 0.7 1.2 0.9 0.2 1.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 51.3 293.1 0.0 19.0 2.8 127.1 539.8 0.6 0.0 169.3 137.4 0.2 268.8 1515.8 80.9 0.0 6.0 0.4 1026.4 0.0 74.1 4.6 301.9 33.9 4.8 522.1 0.0 0.1 835.1 4.5 6.0 2605.5 365.3 43.9 0.0 0.0 1.7 240.8 0.0 0.1 3710.4 386.6 0.8 0.3 0.4 0.3 6.5 3.6 0.0 1.0 0.0 0.0 0.0 0.0 303.1 1101.6 0.0 2.6 426.9 517.9 0.2 781.0 0.0 0.0 0.0 76.9 0.4 0.2 5.3 2.8 3.3 13.1 0.0 1543.1 1017.8 AGR3 "BCMP11, hAG-3, HAG3, PDIA18" ENSG00000173467 "Anterior gradient 3, protein disulphide isomerase family member" Q8TD06 7 16859412-16881987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 225.2;intestine: 237.6;lung: 152.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 861.1;Intestinal goblet cells: 701.9;Paneth cells: 744.5;Proximal enterocytes: 1051.2;Respiratory ciliated cells: 1771.2;Undifferentiated cells: 495.4" "Cancer enhanced" "Detected in many" "breast cancer: 104.5" "Region enhanced" "Detected in some" "midbrain: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "OE19: 109.8;T-47d: 339.3" "Region enriched" "Detected in some" 5 "olfactory bulb: 4.6" HPA053942 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA 67000 "Cluster 9: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Endoplasmic reticulum" Vesicles "HPA053942: AB_2682317" "unprognostic (2.18e-2)" "unprognostic (2.02e-1)" "unprognostic (2.13e-1)" "unprognostic (9.59e-2)" "unprognostic (3.32e-3)" "unprognostic (3.08e-2)" "unprognostic (1.49e-1)" "unprognostic (1.46e-1)" "unprognostic (7.29e-2)" "unprognostic (1.13e-1)" "unprognostic (8.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.96e-1)" "unprognostic (6.66e-2)" "unprognostic (1.57e-1)" 0.6 0.1 0.0 11.0 0.0 0.0 69.6 0.0 0.2 25.0 0.1 219.9 167.2 8.7 0.0 1.5 225.2 48.3 0.1 0.1 0.4 2.5 0.3 152.7 0.2 2.0 3.4 0.3 10.7 0.0 21.2 0.8 1.0 4.8 214.9 0.0 30.9 0.8 0.0 1.5 237.6 8.7 0.7 0.3 99.9 0.2 0.2 0.0 7.3 0.0 0.8 27.6 0.2 0.5 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 109.8 0.0 0.0 0.0 2.3 8.1 0.0 1.3 0.4 0.0 0.6 0.0 0.0 339.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 2.0 3.4 1.0 0.7 0.2 0.5 0.7 333.3 408.1 0.3 1.4 2.7 12.5 108.5 0.0 0.0 105.1 51.9 0.1 31.5 319.9 29.5 0.0 3.4 0.7 380.0 1.9 30.4 0.0 861.1 7.4 1.9 112.7 0.0 0.2 71.4 3.3 5.3 71.4 39.2 20.8 0.0 0.0 0.0 0.5 0.0 0.2 701.9 134.3 0.0 0.3 0.0 0.3 2.3 0.0 0.0 0.6 0.0 0.0 0.0 0.1 16.6 744.5 0.0 0.4 7.1 1051.2 0.0 1771.2 0.0 0.0 0.0 27.9 0.0 0.1 0.0 9.8 2.2 4.1 0.0 495.4 117.9 AGRN AGRIN ENSG00000188157 Agrin O00468 1 1020120-1056118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Differentiation "Developmental protein" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 94.5;Collecting duct cells: 156.3;Ductal cells: 91.2;Pancreatic endocrine cells: 87.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 205.3;EFO-21: 236.9;HaCaT: 210.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040090 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 20000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA040090: AB_10805603" "unprognostic (8.04e-2)" "unprognostic (8.25e-3)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (2.82e-3)" "unprognostic (1.32e-1)" "unprognostic (3.33e-2)" "unprognostic (9.49e-3)" "unprognostic (1.06e-1)" "unprognostic (8.46e-2)" "unprognostic (8.49e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-1)" "unprognostic (1.31e-2)" 11.4 2.7 8.7 4.3 5.5 2.0 14.7 0.1 13.9 14.4 8.9 10.9 7.9 13.7 1.8 15.6 14.6 7.3 9.9 5.8 0.0 44.0 13.3 19.8 1.6 16.0 1.4 5.5 28.0 3.9 8.3 5.1 6.1 14.4 1.5 0.8 24.8 8.2 4.2 16.5 9.6 2.9 2.2 6.3 13.4 9.7 7.9 2.6 34.7 2.0 1.6 16.2 11.6 9.9 124.3 75.1 11.1 42.7 2.4 3.0 122.1 61.4 19.6 39.7 24.5 60.6 205.3 2.3 236.9 9.6 19.3 210.1 4.1 75.6 4.7 4.4 28.6 0.2 102.1 54.2 17.1 1.8 23.1 10.5 32.2 12.6 27.7 55.9 7.2 1.7 25.7 0.7 3.5 93.0 0.8 17.6 28.4 39.7 54.5 20.1 27.0 18.5 70.0 51.4 2.4 25.9 124.8 129.1 121.9 12.7 114.8 7.4 107.8 47.7 169.0 6.4 50.6 1.2 0.6 3.5 30.4 10.8 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 5.5 0.1 13.9 5.8 0.0 16.0 1.4 6.1 2.2 7.9 9.9 27.4 25.6 8.8 15.0 2.2 15.0 9.2 94.5 19.9 1.4 32.7 39.2 3.1 61.5 42.0 156.3 8.4 1.6 0.9 29.9 1.9 91.2 0.4 37.2 14.0 29.0 6.7 1.7 23.1 16.9 4.8 8.7 17.9 62.7 2.5 7.2 21.8 13.1 4.1 5.0 7.8 11.6 36.7 2.9 10.1 1.0 5.6 4.3 24.9 12.2 15.6 10.5 0.0 15.1 29.6 87.3 17.7 2.6 0.6 22.3 18.1 16.0 33.0 5.3 6.6 3.3 23.3 0.8 11.4 11.7 6.0 1.2 2.9 2.3 18.3 21.2 AGRP "Agrt, ART, ASIP2" ENSG00000159723 "Agouti related neuropeptide" O00253 16 67482571-67483547 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 122.5;epididymis: 37.1" "Group enriched" "Detected in some" 5 "Distal tubular cells: 3.9;Hofbauer cells: 8.8;Leydig cells: 3.1;Macrophages: 4.5;Peritubular cells: 2.6;Theca cells: 5.0" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in many" 60 "hypothalamus: 122.5" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "CACO-2: 1.2" "Region enriched" "Detected in single" 16 "hypothalamus: 16.0" "Region enhanced" "Detected in single" "hypothalamus: 2.0" HPA041017 Enhanced Supported "Secreted in brain" NA NA 255000 "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "HPA041017: AB_10795498" "unprognostic (1.32e-1)" "unprognostic (6.26e-2)" "unprognostic (1.13e-1)" "unprognostic (4.16e-1)" "unprognostic (3.15e-1)" "unprognostic (1.10e-1)" "unprognostic (3.61e-1)" "unprognostic (3.34e-1)" "unprognostic (4.68e-1)" "unprognostic (1.29e-1)" "unprognostic (6.74e-2)" "unprognostic (3.17e-1)" "unprognostic (2.80e-1)" "unprognostic (1.72e-1)" "unprognostic (5.63e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-2)" 0.0 12.4 1.2 0.2 1.0 0.2 0.0 0.8 2.0 0.0 1.6 0.1 0.0 0.0 37.1 0.0 0.0 0.0 0.1 1.0 122.5 1.0 0.1 3.7 0.4 1.7 1.1 0.1 0.0 0.2 0.7 0.1 1.0 0.1 0.0 0.2 0.0 0.0 0.1 0.6 0.3 0.0 0.3 0.5 0.3 0.4 2.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.3 0.4 0.0 0.1 0.1 0.0 1.6 0.5 0.9 1.1 0.3 0.7 0.2 0.3 0.7 0.4 0.6 0.6 0.2 0.0 0.4 0.5 0.3 0.4 1.2 1.0 0.8 2.0 1.0 122.5 1.7 1.1 1.0 0.3 2.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.3 0.0 0.1 0.0 0.6 0.0 0.0 8.8 0.0 0.1 0.0 0.0 0.6 0.0 0.4 3.1 4.5 0.0 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 5.0 0.0 0.0 AGT SERPINA8 ENSG00000135744 Angiotensinogen P01019 1 230690776-230745576 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1603.7" "Group enriched" "Detected in many" 9 "Cholangiocytes: 985.1;Hepatocytes: 2244.9" "Cancer enriched" "Detected in all" 4 "liver cancer: 1163.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 646.2;THP-1: 243.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025798 Supported "Secreted to blood" NA NA 5940000 65000000000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB025798: " "unprognostic (7.77e-2)" "unprognostic (4.46e-1)" "unprognostic (2.15e-2)" "unprognostic (2.07e-2)" "unprognostic (2.67e-1)" "unprognostic (3.61e-2)" "unprognostic (5.75e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (4.46e-2)" "unprognostic (4.32e-3)" "unprognostic (6.70e-2)" "unprognostic (9.28e-2)" "unprognostic (4.42e-3)" "unprognostic (2.17e-1)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" 11.7 14.6 252.9 2.6 259.8 0.4 4.4 267.5 243.6 9.7 138.2 5.6 2.5 3.2 1.9 2.6 6.0 92.7 154.7 236.0 242.1 52.5 1603.7 5.1 1.0 352.4 314.4 3.5 7.9 6.0 25.8 0.7 304.9 16.3 3.6 26.4 4.9 2.2 43.6 2.0 9.7 5.8 340.5 1.3 4.9 4.1 273.5 1.7 13.2 25.8 0.1 7.0 4.5 322.4 0.2 0.4 0.2 0.2 15.6 0.0 0.9 0.6 0.2 0.0 0.0 80.6 0.1 0.3 0.7 0.2 0.7 0.7 0.0 0.0 0.0 11.4 0.2 0.2 0.3 646.2 1.9 1.0 0.5 26.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 5.5 0.7 0.0 0.2 0.6 0.6 0.1 0.2 0.3 2.4 0.1 0.1 0.3 0.9 0.6 0.4 0.1 5.5 0.1 0.0 243.6 0.1 0.4 1.3 0.4 1.2 3.5 47.0 0.4 0.4 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.9 259.8 267.5 243.6 236.0 242.1 352.4 314.4 304.9 340.5 273.5 322.4 0.8 0.0 1.7 140.0 11.3 0.6 1.1 0.0 0.0 4.7 0.8 0.3 60.0 985.1 0.6 3.7 35.5 0.1 0.0 0.0 25.4 169.8 62.2 0.3 0.4 5.5 0.0 50.8 0.3 10.0 0.2 27.2 0.5 0.1 0.0 0.0 39.3 2244.9 2.1 3.3 1.5 1.1 0.0 56.9 0.4 48.5 4.1 0.9 8.8 5.6 0.6 75.1 0.0 3.5 6.8 13.7 1.2 3.4 0.0 26.2 24.2 146.9 0.1 49.8 13.1 7.2 94.1 0.4 0.4 0.0 0.0 0.7 3.9 0.0 0.4 1.9 AGTPBP1 "CCP1, KIAA1035, Nna1" ENSG00000135049 "ATP/GTP binding protein 1" Q9UPW5 9 85546539-85742029 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 60.1;brain: 73.4;retina: 46.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.7;Inhibitory neurons: 163.0;Oligodendrocytes: 463.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057208, HPA071094" Approved Approved Nucleoli,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli, Vesicles" "HPA057208: AB_2683370, HPA071094: " "unprognostic (2.15e-1)" "unprognostic (3.78e-2)" "unprognostic (4.93e-3)" "unprognostic (6.12e-2)" "unprognostic (1.42e-1)" "unprognostic (8.95e-3)" "unprognostic (1.86e-2)" "unprognostic (1.65e-1)" "unprognostic (1.71e-1)" "unprognostic (8.26e-3)" "unprognostic (5.69e-3)" "unprognostic (6.31e-2)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-1)" "unprognostic (9.60e-3)" "unprognostic (1.25e-1)" 8.4 5.5 31.1 9.5 44.3 60.1 6.2 23.2 36.3 4.7 0.0 5.1 3.7 4.9 3.9 5.3 4.6 5.3 12.2 20.1 30.3 6.9 4.6 14.4 9.4 30.5 28.6 3.6 6.7 7.5 5.3 6.1 31.5 4.7 5.8 46.5 4.1 3.0 16.5 6.2 5.1 6.5 32.0 14.8 5.5 14.1 34.3 12.4 5.8 20.5 8.4 5.7 4.3 73.4 5.1 9.6 27.9 11.1 5.6 6.0 10.6 7.4 6.4 7.4 8.4 5.2 8.6 31.3 6.2 7.7 13.2 2.9 13.0 9.4 6.9 33.6 11.8 5.3 11.5 9.3 11.8 24.5 6.2 5.8 10.8 7.0 23.5 4.8 11.9 15.9 6.7 24.5 3.3 8.0 19.3 14.5 19.3 18.1 6.8 17.3 10.2 9.8 12.8 5.4 33.5 23.7 8.4 9.1 15.4 26.1 3.5 7.8 12.0 4.8 8.5 30.4 8.9 16.7 14.8 14.3 10.1 23.5 9.8 37.4 14.4 12.7 9.0 8.4 8.8 2.3 4.4 7.0 15.6 1.7 3.7 7.0 21.2 6.8 6.7 2.5 5.1 9.6 31.1 44.3 23.2 36.3 20.1 30.3 30.5 28.6 31.5 32.0 34.3 73.4 22.3 64.1 12.8 46.0 14.3 7.9 2.6 2.9 8.0 38.0 4.7 4.8 48.3 0.0 13.8 3.7 102.2 4.1 41.8 4.3 7.9 5.7 52.5 29.3 8.6 12.0 7.7 16.8 176.7 4.0 4.3 6.9 9.2 22.0 27.1 9.2 8.2 3.7 8.1 35.3 163.0 5.6 6.1 35.4 24.1 53.9 1.8 42.8 3.6 61.8 46.6 16.7 47.4 82.9 463.5 5.1 1.2 2.6 26.2 3.8 3.2 9.8 14.7 59.1 13.1 9.3 10.4 46.6 29.2 9.2 10.7 2.9 26.3 6.4 4.7 2.3 AGTRAP ATRAP ENSG00000177674 "Angiotensin II receptor associated protein" Q6RW13 1 11736084-11754802 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 446.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 196.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044120 Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Golgi apparatus" "HPA044120: AB_10960748" "unprognostic (1.08e-3)" "unprognostic (2.98e-3)" "unprognostic (6.10e-2)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (7.92e-3)" "prognostic unfavorable (6.57e-7)" "unprognostic (4.44e-2)" "unprognostic (7.96e-2)" "unprognostic (4.31e-2)" "unprognostic (1.61e-2)" "unprognostic (7.22e-2)" "unprognostic (1.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (2.33e-3)" "unprognostic (5.89e-2)" 44.1 50.3 26.6 30.2 28.5 132.3 44.3 27.1 32.4 34.6 44.0 29.3 11.2 24.7 47.7 53.6 48.3 25.2 37.0 24.5 30.5 65.8 29.5 62.3 23.4 37.3 28.8 26.9 67.3 25.7 31.2 22.0 31.3 79.1 9.3 3.4 39.0 21.0 54.3 38.8 25.7 20.3 28.4 83.4 33.7 24.7 31.8 11.3 40.8 12.4 13.3 43.9 43.3 31.1 55.9 66.7 16.7 36.9 27.5 34.9 30.5 28.6 49.0 34.8 30.2 42.0 129.7 5.4 126.7 35.4 87.3 45.8 27.9 135.3 10.7 3.1 61.5 1.6 38.4 51.8 84.9 27.6 64.3 34.6 105.4 112.9 59.2 42.4 46.9 17.3 73.8 52.8 19.8 44.6 13.7 80.9 29.7 24.0 67.3 4.6 15.0 27.5 56.7 5.2 14.6 22.0 52.5 26.4 48.4 22.3 59.8 57.4 26.0 44.1 30.8 70.3 30.9 19.6 24.2 33.3 111.7 196.1 20.7 483.4 844.2 694.6 185.7 442.7 90.4 47.0 66.9 109.8 312.2 38.2 72.0 93.5 756.8 73.0 385.2 25.5 90.8 577.4 26.6 28.5 27.1 32.4 24.5 30.5 37.3 28.8 31.3 28.4 31.8 31.1 46.2 22.4 27.4 3.9 12.1 11.6 30.7 112.4 16.5 1.0 54.8 56.0 12.0 32.9 41.6 36.8 6.2 15.7 60.1 6.9 9.8 95.5 20.6 75.3 30.8 36.1 7.2 21.0 0.2 446.7 92.4 45.3 11.2 41.1 88.0 19.1 42.1 7.7 118.3 3.3 0.2 12.3 20.3 143.5 18.9 23.4 37.9 97.8 28.4 1.9 107.4 19.4 122.6 0.5 7.0 96.9 22.5 27.1 8.6 66.5 8.6 55.3 78.5 5.6 13.1 13.0 23.8 3.5 36.1 34.4 13.5 13.1 45.0 50.4 18.2 25.2 AHSG "A2HS, FETUA, HSGA" ENSG00000145192 "Alpha 2-HS glycoprotein" P02765 3 186613060-186621318 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Mineral balance" "Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4302 "liver: 5817.6" "Cell type enriched" "Detected in some" 38 "Hepatocytes: 1242.5" "Cancer enriched" "Detected in some" 284 "liver cancer: 1231.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 78 "Hep G2: 2287.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001524, HPA001525, CAB026209" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 864000000000 110000000000 "Cluster 48: NK-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "CAB026209: , HPA001524: AB_1078851, HPA001525: AB_1078849" "unprognostic (6.40e-2)" "unprognostic (1.31e-1)" "unprognostic (2.03e-2)" "unprognostic (3.20e-2)" "unprognostic (1.07e-2)" "unprognostic (1.16e-2)" "unprognostic (7.47e-3)" "unprognostic (3.05e-1)" "unprognostic (5.27e-2)" "unprognostic (8.64e-2)" "unprognostic (3.99e-7)" "unprognostic (5.21e-2)" "unprognostic (5.21e-2)" "unprognostic (1.04e-1)" 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 1.3 5817.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 0.0 0.7 0.7 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.9 1.0 2287.3 0.0 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 3.5 0.0 0.0 1.1 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 1.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.2 0.0 0.0 0.0 0.2 0.0 0.1 3.9 0.2 4.3 0.2 0.1 0.9 0.0 32.0 0.6 0.6 2.4 0.1 0.0 0.1 0.0 0.0 28.2 1242.5 1.3 0.0 0.1 0.0 0.0 32.4 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 2.0 0.0 0.0 0.1 AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 183.5;liver: 104.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 242.6;Proximal tubular cells: 595.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.1;myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 208.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Enhanced Supported Mitochondria "Intracellular and membrane" NA Yes 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavorable (4.36e-4)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" 24.7 1.9 19.5 6.6 21.0 4.9 26.6 17.8 20.8 6.1 17.5 19.7 4.3 7.0 4.2 23.4 7.6 13.7 51.7 21.4 21.2 183.5 104.0 2.8 1.6 19.0 22.8 4.6 1.2 18.3 4.7 8.3 22.8 16.2 14.0 21.9 9.6 12.7 1.7 27.4 6.6 21.4 18.5 1.2 15.0 11.3 22.7 5.7 2.5 38.8 3.3 19.1 11.8 21.1 73.2 5.0 5.6 23.9 51.6 48.7 12.0 12.1 15.0 25.6 70.8 108.1 8.6 39.1 31.0 19.0 32.1 46.1 18.8 89.9 101.9 33.0 21.5 37.9 21.9 208.6 2.5 29.9 4.6 27.2 49.6 25.1 73.0 42.2 0.9 12.2 48.0 0.6 39.6 31.2 1.1 1.3 24.6 1.0 42.5 0.2 41.0 7.1 37.8 3.2 20.5 15.4 21.6 1.5 16.7 25.8 29.7 12.9 4.2 42.4 36.2 3.3 20.9 39.5 18.8 2.1 68.7 10.9 2.5 0.9 3.1 0.0 0.1 0.6 0.2 0.2 0.1 0.2 2.7 0.1 0.1 0.1 0.4 0.3 0.1 0.4 0.0 0.8 19.5 21.0 17.8 20.8 21.4 21.2 19.0 22.8 22.8 18.5 22.7 21.1 11.2 0.0 0.5 51.2 4.7 49.7 23.6 44.2 63.7 24.5 48.9 44.7 105.7 52.9 14.3 31.3 2.1 2.2 0.6 15.8 56.7 18.6 3.4 30.1 8.2 19.6 5.4 13.9 17.1 12.1 21.1 11.4 27.5 52.2 0.0 36.4 11.7 242.6 3.3 16.8 7.7 8.7 24.4 7.8 9.2 5.8 4.1 6.9 24.9 3.7 5.7 32.7 0.0 9.5 2.5 31.9 4.3 9.4 0.4 38.7 18.8 595.5 12.3 6.5 6.6 5.6 18.8 1.8 9.5 43.1 74.3 4.9 3.6 0.7 23.1 20.4 AKAP10 "D-AKAP2, MGC9414, PRKA10" ENSG00000108599 "A-kinase anchoring protein 10" O43572 17 19904302-19978343 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 84.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028901 Approved Supported "Plasma membrane,Cytosol" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA028901: AB_10602227" "unprognostic (2.17e-2)" "unprognostic (3.48e-2)" "unprognostic (5.33e-1)" "unprognostic (1.40e-1)" "unprognostic (1.50e-1)" "unprognostic (5.51e-2)" "unprognostic (1.59e-3)" "unprognostic (3.88e-1)" "unprognostic (7.69e-3)" "unprognostic (1.89e-1)" "unprognostic (3.59e-2)" "unprognostic (3.21e-2)" "unprognostic (3.21e-2)" "unprognostic (2.49e-2)" "unprognostic (7.15e-2)" "unprognostic (2.16e-2)" "unprognostic (5.20e-2)" 11.4 13.3 10.5 12.3 12.4 10.6 12.3 11.4 13.6 11.5 15.1 11.4 9.5 12.4 8.8 10.6 10.4 10.7 7.4 11.3 11.6 13.1 8.1 11.0 16.0 9.9 10.7 13.5 8.4 15.1 7.5 12.2 10.6 10.9 11.6 15.3 9.8 11.7 7.2 9.5 10.1 13.3 10.4 14.9 11.1 14.2 13.8 14.1 15.1 9.4 12.5 11.3 10.2 14.7 18.1 21.3 13.9 9.7 18.0 22.5 25.7 20.6 21.9 22.4 26.7 23.2 10.6 15.4 13.6 16.4 19.4 18.8 18.1 17.2 30.4 12.8 15.4 13.2 20.2 11.4 17.0 9.7 20.7 19.1 21.1 20.5 25.1 25.0 18.3 18.5 8.6 7.5 23.6 13.1 18.1 14.3 9.1 25.1 7.2 11.8 45.5 8.1 18.7 11.3 4.7 14.1 23.6 11.0 19.7 84.8 26.7 10.7 16.1 17.2 14.2 14.8 19.3 9.3 10.7 18.8 22.8 11.5 17.0 4.9 9.7 12.6 8.6 14.4 8.0 8.4 8.4 9.4 8.5 9.2 10.0 8.9 33.8 7.6 13.9 6.3 7.1 4.3 10.5 12.4 11.4 13.6 11.3 11.6 9.9 10.7 10.6 10.4 13.8 14.7 13.4 3.2 12.3 71.2 24.4 7.0 9.7 8.9 10.2 24.6 11.1 9.0 8.4 21.5 11.9 5.5 16.7 14.9 16.8 15.8 1.9 9.9 12.8 11.0 14.8 12.6 7.2 15.2 55.1 7.2 11.1 11.7 14.8 10.8 10.1 18.0 16.8 13.6 16.5 33.7 54.6 9.9 12.2 35.1 10.5 13.9 15.2 21.4 5.4 61.8 32.3 11.7 25.7 51.8 78.5 7.9 15.2 13.9 11.2 15.6 14.6 5.7 15.3 23.2 19.7 10.5 11.2 23.1 23.6 11.0 7.7 14.0 19.0 15.6 11.8 12.1 AKAP6 "ADAP6, AKAP100, KIAA0311, mAKAP, PRKA6" ENSG00000151320 "A-kinase anchoring protein 6" Q13023 14 32329298-32837684 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.8;heart muscle: 54.6;skeletal muscle: 47.5;tongue: 50.7" "Group enriched" "Detected in many" 6 "Excitatory neurons: 601.6;Inhibitory neurons: 663.1;Oligodendrocyte precursor cells: 412.7;Oligodendrocytes: 1162.5" "Cancer enhanced" "Detected in many" "glioma: 2.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive B-cell: 3.5" "Lineage enriched" "Detected in single" 6 "B-cells: 3.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001983, HPA048741" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB001983: , HPA048741: AB_2680506" "unprognostic (1.99e-1)" "unprognostic (9.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.37e-1)" "unprognostic (2.52e-1)" "unprognostic (4.33e-2)" "unprognostic (1.41e-4)" "unprognostic (1.81e-3)" "unprognostic (1.93e-2)" "unprognostic (4.49e-3)" "unprognostic (1.24e-3)" "unprognostic (3.54e-1)" "unprognostic (3.33e-16)" "unprognostic (8.57e-2)" "unprognostic (1.27e-1)" "unprognostic (5.14e-3)" "unprognostic (1.79e-3)" 1.6 5.6 21.0 2.5 31.4 0.5 4.6 20.3 24.6 1.6 0.0 5.5 1.8 3.9 5.6 5.4 2.9 3.7 54.6 16.9 36.7 2.9 2.1 2.3 0.8 52.0 34.9 2.5 0.8 3.5 3.6 4.5 51.9 2.0 2.2 13.6 2.6 1.2 47.5 1.2 2.4 7.7 22.4 0.8 2.0 5.9 34.8 0.9 4.8 50.7 0.7 4.2 1.5 59.8 0.3 0.8 1.0 0.9 0.2 1.7 0.2 1.3 3.6 0.2 0.4 1.1 1.0 1.4 0.9 15.8 0.6 0.8 1.2 1.4 0.5 1.3 1.0 1.3 1.5 1.1 0.5 0.1 0.3 1.8 1.3 0.0 0.4 0.6 0.1 2.1 0.3 4.1 1.1 0.8 0.7 0.2 0.2 1.1 1.1 0.7 4.9 0.6 0.4 1.2 5.2 4.2 1.1 0.7 3.2 0.7 2.9 0.1 0.3 0.2 0.8 0.8 0.5 2.5 2.4 0.6 1.5 0.1 5.4 0.3 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.2 3.5 0.4 0.6 0.5 0.1 0.1 0.4 0.0 0.3 21.0 31.4 20.3 24.6 16.9 36.7 52.0 34.9 51.9 22.4 34.8 59.8 0.6 6.4 2.7 111.3 2.2 2.3 2.9 1.0 5.2 49.2 8.7 3.0 108.0 0.0 4.9 1.8 50.1 0.8 0.1 1.1 0.0 0.8 32.4 6.7 0.4 1.7 1.2 0.0 601.6 0.5 0.3 6.3 0.0 1.4 1.3 0.6 1.1 2.7 1.2 26.9 663.1 0.6 4.1 0.6 1.6 13.7 14.6 1.1 7.2 23.4 0.7 2.5 0.0 412.7 1162.5 0.3 0.1 33.1 2.0 1.1 1.9 1.5 23.6 21.5 19.7 25.8 14.3 25.9 1.3 1.1 1.6 0.4 0.6 3.4 0.9 0.9 AKIRIN2 "C6orf166, dJ486L4.2, FLJ10342" ENSG00000135334 "Akirin 2" Q53H80 6 87674860-87702233 "Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA064239 Supported Nucleoplasm No Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA064239: AB_2685222" "unprognostic (9.65e-2)" "unprognostic (2.56e-1)" "unprognostic (8.25e-2)" "unprognostic (8.09e-2)" "unprognostic (3.58e-1)" "unprognostic (1.87e-2)" "unprognostic (1.07e-1)" "unprognostic (5.38e-2)" "unprognostic (6.17e-2)" "unprognostic (6.60e-3)" "unprognostic (1.62e-2)" "unprognostic (2.56e-1)" "unprognostic (1.48e-2)" "unprognostic (9.62e-2)" "unprognostic (9.55e-2)" "unprognostic (2.23e-3)" "unprognostic (1.02e-1)" 32.9 37.1 29.0 23.8 32.5 70.5 26.0 26.5 37.6 22.7 27.8 19.8 12.7 24.6 23.7 33.2 22.6 15.3 30.9 34.0 34.0 20.8 31.2 33.2 28.4 26.9 28.8 25.6 13.2 17.8 23.4 18.5 26.4 17.0 12.5 29.7 24.5 11.7 97.4 22.9 22.9 16.4 29.5 49.0 16.8 24.1 35.7 31.2 17.2 42.6 30.3 23.2 25.0 30.9 23.9 24.7 71.0 40.1 43.1 29.6 41.4 41.1 25.7 33.2 32.3 39.7 18.0 62.2 44.1 42.1 55.1 36.2 39.1 29.6 37.9 79.2 48.5 36.3 21.8 89.7 47.1 31.4 30.2 34.6 29.9 41.0 40.2 32.5 36.6 24.3 71.2 42.2 43.5 30.7 9.9 64.9 51.0 20.3 38.1 38.7 50.2 25.7 41.7 20.8 53.0 50.3 24.9 14.8 44.2 40.1 17.9 73.9 47.6 27.5 18.8 23.5 54.6 40.9 48.4 38.8 30.4 40.2 45.1 76.1 57.8 64.8 28.1 73.2 29.2 41.6 27.4 27.6 55.0 32.6 21.4 23.1 144.4 36.6 75.6 75.1 39.1 35.0 29.0 32.5 26.5 37.6 34.0 34.0 26.9 28.8 26.4 29.5 35.7 30.9 49.9 25.6 19.8 10.4 88.2 96.5 192.2 101.9 80.8 13.0 31.8 28.8 22.5 35.8 43.7 18.4 8.4 45.1 94.4 17.1 45.0 30.9 58.0 44.9 34.3 45.6 12.1 45.4 15.6 14.7 71.0 51.1 16.3 39.9 33.6 47.2 44.6 29.9 77.0 11.8 14.8 10.9 69.2 104.4 167.0 100.9 35.8 142.8 74.7 19.7 46.7 80.5 33.0 17.6 15.1 29.6 21.7 28.2 69.4 119.7 19.0 53.5 17.9 17.0 6.6 62.2 39.9 70.6 63.0 92.6 92.9 136.5 99.5 54.2 12.6 191.0 AKR1C1 "DD1, DDH, DDH1, HAKRC, MBAB" ENSG00000187134 "Aldo-keto reductase family 1 member C1" Q04828 10 4963253-4983283 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 623.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 253.8;Basal squamous epithelial cells: 262.4;Cholangiocytes: 284.5;Exocrine glandular cells: 328.0;Hepatocytes: 597.7;Squamous epithelial cells: 229.3;Urothelial cells: 306.0" "Cancer enhanced" "Detected in many" "liver cancer: 64.2;lung cancer: 53.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 8 "ASC diff: 2988.3;Hep G2: 5415.7;OE19: 2297.1" "CAB047303, HPA068265" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "CAB047303: , HPA068265: AB_2685966" "unprognostic (1.54e-2)" "prognostic favorable (3.05e-4)" "unprognostic (4.04e-2)" "unprognostic (8.38e-2)" "unprognostic (3.18e-2)" "unprognostic (7.05e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (8.38e-2)" "unprognostic (4.65e-1)" "unprognostic (1.82e-2)" "prognostic favorable (8.03e-9)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (6.30e-2)" 185.7 14.3 12.3 13.5 16.5 5.8 116.2 16.0 11.5 12.9 6.9 23.2 25.3 6.6 6.6 103.9 11.5 65.7 135.5 10.9 18.7 45.4 623.2 28.9 4.7 22.1 18.4 15.5 23.3 0.8 9.7 1.7 23.2 17.3 12.2 11.5 73.7 12.5 120.4 35.3 23.4 8.7 19.6 4.1 142.9 13.0 22.2 4.6 46.7 27.3 7.8 71.1 31.3 20.3 0.0 429.6 2.4 426.7 2988.3 358.2 0.2 13.7 95.9 5.4 4.1 8.4 0.5 0.0 6.1 97.7 72.5 3.6 1.6 22.4 2.5 0.1 0.2 12.6 65.6 5415.7 30.0 1.8 0.0 183.9 27.3 44.2 26.7 0.4 10.2 2.9 95.8 0.4 74.7 2.4 0.1 0.4 1.2 2297.1 1.5 0.1 0.8 4.2 24.3 81.4 0.4 1.7 23.8 0.7 0.8 1.3 0.5 7.8 85.3 36.0 2.3 97.6 4.5 1.6 0.5 0.3 129.3 12.1 0.9 1.5 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.3 0.1 0.0 0.2 0.1 0.2 12.3 16.5 16.0 11.5 10.9 18.7 22.1 18.4 23.2 19.6 22.2 20.3 21.6 67.3 34.4 2.0 2.4 21.2 27.8 253.8 262.4 3.1 7.6 1.0 3.2 284.5 144.5 62.5 0.0 0.1 0.2 5.9 13.7 67.0 24.0 3.3 1.7 17.1 1.8 52.6 3.4 328.0 0.1 176.3 139.1 4.6 4.5 0.8 21.0 597.7 0.4 0.0 3.1 6.8 20.3 16.1 15.6 9.9 151.6 3.3 106.7 13.1 4.6 51.5 0.0 4.5 0.5 120.2 3.6 147.4 0.4 41.3 20.2 61.9 72.2 4.5 0.0 16.4 24.3 1.9 1.1 229.3 20.5 0.1 2.1 6.4 20.3 306.0 AL021546.1 ENSG00000111780 "Novel protein" 12 120438198-120460006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CACO-2: 8.9;HEK 293: 11.5;U-266/84: 10.4" HPA062394 Uncertain Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA062394: AB_2684749" "unprognostic (3.79e-2)" "unprognostic (1.74e-1)" "unprognostic (2.79e-1)" "unprognostic (2.90e-1)" "unprognostic (1.71e-1)" "unprognostic (1.33e-1)" "unprognostic (9.54e-4)" "unprognostic (2.04e-1)" 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.2 0.4 0.1 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.4 0.3 0.4 0.4 0.1 0.0 0.1 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.4 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.4 2.0 2.6 0.0 0.6 0.0 0.0 0.0 1.8 0.3 0.5 0.0 8.9 0.0 0.5 3.2 0.0 0.8 0.9 0.0 0.5 0.0 1.6 11.5 0.7 0.0 0.0 0.0 4.1 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.9 0.2 0.0 0.0 3.2 0.4 0.2 0.0 4.6 1.8 1.2 1.0 0.0 0.0 4.5 0.3 2.9 0.7 0.0 0.0 0.8 0.4 2.4 1.5 0.4 0.0 1.2 0.9 10.4 3.8 0.6 1.3 0.0 1.6 6.1 5.6 5.0 8.9 5.6 4.9 3.0 5.7 11.0 3.8 3.3 3.1 1.3 2.2 6.9 7.9 5.4 4.2 0.1 0.3 0.2 0.4 0.2 0.3 0.4 0.3 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL049629.2 ENSG00000284969 "Novel protein" 11 33698261-33722467 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Ductal cells: 9.1;Exocrine glandular cells: 14.4;Pancreatic endocrine cells: 44.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 42.8;HUVEC TERT2: 55.1;TIME: 66.2;U-2197: 57.6" HPA026494 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Vesicles" "HPA026494: AB_1846321" 2.5 0.7 1.5 2.3 1.4 1.5 1.1 1.5 1.6 0.5 2.5 0.7 1.4 1.3 1.8 1.2 0.6 2.1 1.1 1.4 1.7 1.6 0.8 1.7 0.3 1.8 2.0 0.6 0.7 1.0 1.5 1.8 0.5 0.7 0.6 2.4 0.7 3.5 0.3 0.3 0.6 1.8 0.5 2.9 1.1 1.8 0.2 0.8 1.1 1.4 2.3 2.1 1.3 3.3 0.2 2.4 3.4 7.9 0.1 18.5 8.4 2.3 2.2 0.1 9.6 0.0 2.3 12.5 1.1 2.2 0.3 42.8 4.0 2.0 0.4 0.3 7.1 0.8 0.8 0.4 1.2 3.0 2.7 1.0 14.7 1.9 55.1 0.3 0.5 7.4 15.4 1.0 1.8 0.8 0.5 1.3 24.8 0.4 1.5 1.3 4.9 2.2 0.0 0.3 2.0 3.4 7.3 0.2 1.0 0.0 66.2 7.0 2.7 57.6 7.4 3.8 3.7 0.3 16.0 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.5 1.4 1.5 1.6 1.4 1.7 1.8 2.0 1.8 1.8 1.8 2.1 0.5 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.7 0.2 2.1 0.0 0.0 0.0 14.4 0.0 0.2 0.0 1.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 AL049634.2 ENSG00000260861 "Novel protein, SIRPB1-SIRPD readthrough" 20 1540144-1620009 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 2.7;lymphoid tissue: 2.6;testis: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 78.3;neutrophil: 127.7" "Group enriched" "Detected in many" 7 "granulocytes: 127.7;monocytes: 43.6" "Cell line enhanced" "Detected in some" "HL-60: 3.5;HMC-1: 6.7;NB-4: 2.6;THP-1: 4.0;U-937: 2.1" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" 0.4 0.8 0.1 2.6 0.1 2.7 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.4 0.3 0.2 0.1 0.2 0.0 0.1 0.3 0.1 0.5 0.7 0.8 0.1 0.2 0.1 0.3 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.2 0.3 0.2 0.1 0.6 0.6 0.2 0.8 0.1 3.3 0.5 0.2 0.0 0.0 0.4 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.5 6.7 0.0 0.1 0.2 0.0 1.4 0.0 0.1 0.0 0.0 0.1 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.0 1.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.1 2.1 0.1 0.6 35.3 78.3 0.6 27.5 0.3 0.1 0.0 0.4 12.9 0.0 0.1 0.1 127.7 0.2 43.6 10.4 0.2 26.0 0.1 0.1 0.0 0.3 0.1 0.3 0.1 0.2 0.2 0.2 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL160272.2 ENSG00000285082 "Novel protein" 9 117704157-118072314 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "bone marrow: 1.8;brain: 7.0;choroid plexus: 2.3;retina: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "A549: 1.6" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" 0.2 0.5 2.6 0.3 2.4 1.8 0.4 7.0 3.5 0.1 2.3 0.2 0.1 0.2 0.2 0.1 0.1 0.2 0.2 2.4 2.9 0.3 0.2 0.2 0.5 2.1 1.9 0.1 0.5 0.5 0.2 2.8 0.2 0.2 2.0 0.2 0.1 0.3 0.5 0.4 0.1 0.6 0.5 0.4 0.2 2.3 0.0 0.3 0.2 0.2 0.1 2.8 0.0 1.6 0.5 0.1 0.0 0.1 0.4 0.1 0.1 0.0 0.1 0.6 0.3 0.2 0.1 0.1 0.1 0.4 0.0 0.1 0.2 0.3 0.0 0.5 0.6 0.2 0.0 0.8 0.1 0.2 0.1 0.4 0.1 0.1 0.2 0.1 0.1 0.7 0.3 0.5 0.2 0.5 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.2 0.3 0.3 0.6 0.1 0.3 0.1 0.2 0.0 0.4 0.1 0.2 0.1 0.4 0.7 0.2 0.3 0.4 0.1 0.5 0.4 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.4 0.2 0.2 0.5 0.0 0.1 0.4 0.1 0.0 2.6 2.4 7.0 3.5 2.4 2.9 2.1 1.9 2.8 0.6 2.3 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL162417.1 ENSG00000285245 "Novel protein" 9 133098121-133163914 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.0;REH: 1.1;TIME: 1.1" HPA025961 Uncertain Uncertain Nucleoplasm NA NA "Cluster 42: Epithelial cell lines - Epithelial cell function" Nucleoplasm "HPA025961: AB_2671795" 0.1 0.2 0.0 0.2 0.2 0.4 0.0 0.4 0.3 0.1 0.8 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.7 0.8 1.0 0.6 0.2 0.1 0.8 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.5 0.3 0.1 0.1 0.0 0.7 0.0 0.1 0.6 0.0 0.3 0.3 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.6 0.2 0.0 0.0 0.2 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.3 0.1 0.3 0.7 0.8 0.8 0.3 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL163195.3 ENSG00000259060 "Novel protein" 14 20582892-20609795 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "epididymis: 4.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 68: Epididymis - Unknown function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 AL163636.1 ENSG00000259171 "Novel protein, ANG-RNASE4 readthrough" 14 20684587-20700576 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 115.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 0.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "classical monocyte: 9.9;memory B-cell: 3.6;myeloid DC: 5.8" "Group enriched" "Detected in many" 12 "B-cells: 3.6;dendritic cells: 5.8;monocytes: 9.9" "Cell line enhanced" "Detected in many" "ASC diff: 17.2;ASC TERT1: 38.5;Hep G2: 26.0;HSkMC: 16.9;OE19: 75.0" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "unprognostic (1.88e-1)" "unprognostic (3.10e-2)" "unprognostic (1.34e-1)" "unprognostic (1.08e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-3)" "unprognostic (1.93e-1)" "unprognostic (1.27e-1)" "unprognostic (2.60e-1)" "unprognostic (8.66e-2)" "unprognostic (6.61e-2)" "unprognostic (6.87e-3)" "unprognostic (8.58e-3)" "unprognostic (2.88e-1)" "unprognostic (2.53e-2)" "unprognostic (5.11e-2)" 45.2 5.8 1.0 6.8 0.7 0.1 34.7 0.6 1.6 31.7 1.5 29.5 26.5 25.1 10.6 11.8 27.3 48.0 14.9 0.8 1.5 15.6 115.1 23.7 5.4 1.2 0.9 69.7 19.4 3.3 3.1 2.6 1.1 41.4 35.1 0.3 35.1 16.5 6.7 17.9 31.7 17.9 1.3 3.6 58.4 7.1 0.8 1.5 8.2 14.6 5.1 24.7 25.7 1.6 2.6 0.8 2.0 0.0 17.2 38.5 0.0 2.4 6.4 0.0 1.7 0.0 2.7 0.0 0.0 10.2 2.7 0.8 0.6 0.2 0.0 6.4 0.4 0.4 0.0 26.0 1.3 0.0 0.0 16.9 1.4 0.0 0.9 12.1 0.5 1.8 0.0 11.6 2.9 0.0 0.2 0.5 0.0 75.0 0.3 0.3 1.4 2.1 0.1 0.9 0.0 0.2 4.0 1.6 2.0 0.0 1.9 0.2 1.8 3.3 0.6 2.0 0.4 2.2 1.6 0.0 3.2 0.4 3.8 0.0 9.9 0.0 0.0 0.5 0.3 3.6 0.4 0.2 5.8 1.2 0.2 0.0 0.1 0.0 0.0 1.0 0.5 2.4 1.0 0.7 0.6 1.6 0.8 1.5 1.2 0.9 1.1 1.3 0.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL354761.1 ENSG00000236543 "Lipocalin 1-like" 9 135604345-135619893 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 31 "skin 1: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "BEWO: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL358113.1 ENSG00000285130 "Novel protein" 9 69035747-69255187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 3.2;Alveolar cells type 2: 4.6;Endometrial ciliated cells: 3.8;Glandular and luminal cells: 3.8;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "REH: 1.0" "HPA001813, HPA068304, HPA070714" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA001813: AB_1080764, HPA068304: AB_2685970, HPA070714: AB_2732161" 0.0 0.3 0.1 0.4 0.1 0.1 0.0 0.1 0.5 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.6 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.3 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.1 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.6 0.1 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.7 0.0 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.7 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.6 0.8 0.5 0.1 0.1 0.1 0.1 0.5 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.4 3.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 3.8 0.6 0.5 0.0 0.0 0.0 0.2 0.0 0.3 0.0 3.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 AL365214.2 ENSG00000281613 "Novel ret finger protein-like 4B" 6 112236806-112350094 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "testis: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "RPTEC TERT1: 3.4" HPA059324 Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "HPA059324: " 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL445524.2 ENSG00000287856 "Novel protein" 1 231363797-231528603 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 59.5;neutrophil: 43.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 59.5" "Low cell line specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 21: OE19 - Mitochondria" 4.6 4.4 2.4 3.7 2.6 3.4 4.6 2.6 3.6 1.5 2.1 4.8 4.6 1.2 5.1 2.8 1.5 1.4 1.9 2.4 2.7 4.2 7.3 1.5 1.7 2.7 2.7 1.2 1.9 7.5 2.4 2.8 1.8 5.2 1.1 4.2 1.9 7.1 12.3 6.2 3.2 2.5 2.5 3.0 7.3 2.7 2.3 2.0 5.9 4.8 4.1 3.0 15.9 19.3 5.5 7.1 9.6 9.4 6.0 9.9 7.6 7.2 8.6 12.4 15.7 3.9 3.2 11.1 9.3 6.3 8.5 19.5 13.6 20.4 33.9 7.1 14.0 29.5 10.6 8.9 13.0 13.5 13.3 19.7 15.2 11.1 10.1 7.1 8.9 7.5 5.7 3.7 3.1 4.0 8.4 44.9 14.8 2.4 9.6 5.6 15.3 13.6 4.9 7.8 9.6 9.4 28.7 6.6 8.0 19.0 7.2 7.8 8.4 11.6 27.3 7.0 9.9 3.9 12.9 8.4 17.5 59.5 10.3 18.5 1.1 7.2 0.9 2.1 2.2 1.2 6.2 2.0 2.4 1.7 43.9 1.4 8.2 1.3 2.5 3.2 2.4 2.6 2.6 3.6 2.4 2.7 2.7 2.7 2.8 2.5 2.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL603764.2 ENSG00000286135 "Carbohydrate-binding protein AQN-1-like" 10 122672850-122679494 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 838 "epididymis: 118.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 118.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL645922.1 ENSG00000244255 "Novel complement component 2 (C2) and complement factor B (CFB) protein" 6 31927698-31952048 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 2.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.5;Club cells: 3.1;Fibroblasts: 1.2;Respiratory ciliated cells: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000951, HPA001817, HPA001832" Approved Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 49: Ciliated cells - Cilium organization" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "unprognostic (7.68e-2)" "unprognostic (1.86e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL645941.2 ENSG00000248993 "Novel protein" 6 32937364-32953122 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA012298 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 11: Alveolar cells - Smell perception" "HPA012298: AB_1853927" "unprognostic (1.33e-1)" "unprognostic (2.53e-1)" "unprognostic (4.98e-1)" "unprognostic (5.56e-4)" "unprognostic (3.24e-2)" "unprognostic (4.17e-2)" "unprognostic (1.08e-1)" "unprognostic (1.93e-1)" "unprognostic (3.25e-2)" "unprognostic (3.78e-1)" "unprognostic (1.60e-1)" "unprognostic (8.18e-2)" "unprognostic (4.73e-2)" 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL929554.1 ENSG00000261793 "Novel transcript, TMEM210 and LRRC26 readthrough" 9 137168854-137171984 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "salivary gland: 46.6" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.0" "Immune cell enriched" "Detected in single" 31 "plasmacytoid DC: 3.0" "Lineage enriched" "Detected in single" 31 "dendritic cells: 3.0" "Group enriched" "Detected in some" 5 "REH: 10.3;RPMI-8226: 16.6;SK-BR-3: 11.1;T-47d: 6.4" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" 0.0 0.2 0.1 0.4 0.4 0.1 0.4 2.0 0.5 0.6 0.0 1.0 2.3 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.1 0.2 0.0 1.4 0.0 0.0 0.0 0.1 10.9 0.1 0.0 46.6 0.5 0.0 0.0 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 1.2 0.1 0.2 0.0 10.3 0.0 16.6 0.0 1.3 0.4 0.1 0.0 11.1 0.0 0.0 6.4 0.5 0.0 0.0 0.4 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.4 2.0 0.5 0.1 0.6 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALAS2 ASB ENSG00000158578 "5'-aminolevulinate synthase 2" P22557 X 55009055-55030977 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "bone marrow: 606.2" "Cell type enriched" "Detected in some" 166 "Erythroid cells: 2366.7" "Cancer enhanced" "Detected in single" "renal cancer: 0.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 6 "dendritic cells: 1.6" "Group enriched" "Detected in some" 93 "HEL: 71.7;K-562: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "unprognostic (7.82e-2)" "unprognostic (2.01e-1)" "unprognostic (6.41e-2)" "unprognostic (1.14e-2)" "unprognostic (2.98e-3)" "unprognostic (5.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (8.68e-2)" "unprognostic (4.07e-2)" "unprognostic (2.72e-1)" "unprognostic (3.45e-1)" "unprognostic (2.32e-2)" "unprognostic (6.63e-3)" "unprognostic (4.39e-1)" "unprognostic (1.23e-1)" "unprognostic (1.89e-1)" 1.9 0.5 0.9 0.4 0.9 606.2 0.6 0.8 2.5 0.2 1.6 0.5 0.6 0.1 0.0 0.8 1.1 0.8 3.4 0.7 0.8 2.5 3.2 5.2 0.3 1.8 1.2 0.4 0.3 0.0 1.2 44.9 1.6 0.2 0.0 0.2 1.0 0.2 0.5 0.6 0.3 0.1 1.6 25.2 0.2 0.2 1.0 1.0 1.2 18.2 0.0 0.6 0.7 1.3 0.1 0.0 0.0 0.8 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.6 71.7 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 85.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.2 0.2 0.1 0.4 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.4 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 1.6 0.0 5.9 0.9 0.9 0.8 2.5 0.7 0.8 1.8 1.2 1.6 1.6 1.0 1.3 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.8 0.0 0.1 0.0 0.3 1.8 2366.7 0.0 0.2 1.8 0.3 0.0 0.1 0.0 0.0 1.4 1.3 2.1 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 7.3 14.2 1.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.7 1.1 0.0 0.0 0.1 ALB ENSG00000163631 Albumin P02768 4 73397114-73421482 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 135 "liver: 212494.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 65190.0" "Cancer enriched" "Detected in many" 384 "liver cancer: 14213.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 38 "Hep G2: 4500.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB006262, HPA031024, HPA031025" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" NA NA 40000000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "Endoplasmic reticulum" "CAB006262: AB_425297, HPA031024: AB_2673703, HPA031025: AB_2673704" "unprognostic (1.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.73e-1)" "unprognostic (2.60e-1)" "unprognostic (4.44e-1)" "unprognostic (2.46e-1)" "unprognostic (9.53e-3)" "unprognostic (2.16e-2)" "unprognostic (2.40e-1)" "unprognostic (6.43e-2)" "unprognostic (3.84e-2)" "unprognostic (5.37e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.87e-4)" "unprognostic (7.23e-2)" "unprognostic (1.05e-3)" "unprognostic (1.02e-2)" 8.3 3.7 0.9 0.0 1.0 0.0 5.9 0.6 1.3 1.9 0.6 2.5 0.0 1.8 15.4 2.6 4.3 3.8 8.2 0.7 0.9 465.2 212494.0 6.7 1.3 0.7 0.8 2.5 1569.1 1.0 3.4 4.5 0.7 2.2 0.1 0.5 2.1 0.1 1.9 3.3 2.3 0.0 0.7 37.0 10.1 3.6 1.0 0.3 3.6 0.1 1.4 0.9 1.7 0.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 18.8 0.6 0.0 0.0 1.6 0.0 0.0 0.1 0.6 0.0 31.7 2.1 4500.0 0.0 117.1 3.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 17.0 0.2 0.0 0.1 2.0 0.0 4.0 0.0 0.1 2.1 95.1 0.0 0.0 3.2 0.0 0.0 52.3 0.0 0.0 0.0 0.0 0.0 13.5 0.0 1.4 0.1 0.1 7.0 0.6 32.9 0.1 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.6 1.3 0.7 0.9 0.7 0.8 0.7 0.7 1.0 0.8 0.1 0.0 0.0 1.0 187.5 0.0 0.0 0.0 0.0 0.0 43.4 18.9 0.1 13788.8 0.0 38.6 0.0 1.4 0.6 0.1 72.4 5.3 2.5 0.2 0.1 65.5 1.8 1133.8 0.2 273.8 11.1 0.5 4.6 0.0 0.0 0.1 1252.5 65190.0 8.5 0.0 0.2 0.0 0.0 1764.5 0.0 0.1 0.0 2.9 0.0 0.0 1.0 0.0 0.0 0.0 0.1 160.6 0.0 0.0 0.0 0.2 0.0 686.5 0.0 0.0 0.0 0.0 1.1 0.2 1.3 0.0 0.1 21.2 77.1 0.1 0.0 0.1 ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 311.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" NA NA 2000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" 119.2 105.5 49.6 29.8 51.0 24.8 76.8 49.3 60.3 51.5 62.5 45.7 54.8 38.6 93.4 105.6 50.2 32.0 48.2 47.4 57.5 142.4 206.5 38.5 40.3 50.5 52.1 53.6 44.0 81.9 39.9 38.0 51.4 65.3 50.6 46.4 104.1 45.6 93.6 54.7 48.6 42.0 50.7 37.9 39.5 63.4 49.3 39.0 123.0 56.4 60.1 39.4 43.9 55.6 55.7 53.5 48.7 44.1 152.1 132.8 40.7 71.9 101.5 70.8 61.0 33.4 40.7 0.1 67.1 64.8 34.9 42.8 40.0 70.3 83.0 25.9 50.6 35.3 34.7 36.5 78.2 56.0 36.1 86.0 34.8 75.2 62.5 97.8 62.2 45.9 56.9 48.4 111.7 33.4 37.6 57.6 71.3 145.1 64.7 31.7 62.0 74.3 92.5 52.0 57.7 39.8 51.4 57.1 67.4 65.6 108.8 84.0 61.9 42.5 41.5 52.4 37.1 44.7 62.5 54.8 47.9 52.6 41.7 61.8 35.2 50.9 45.5 37.7 48.8 49.9 43.8 49.6 34.5 46.8 43.8 50.4 51.3 43.0 45.3 21.6 69.8 45.6 49.6 51.0 49.3 60.3 47.4 57.5 50.5 52.1 51.4 50.7 49.3 55.6 56.2 16.0 47.6 12.7 43.3 32.6 43.3 43.8 68.3 25.0 83.0 54.6 46.5 55.8 36.8 51.5 22.9 48.5 39.3 43.9 97.8 42.9 45.4 27.7 39.1 49.4 55.8 28.2 5.6 37.0 76.4 60.6 36.2 20.4 38.0 60.9 59.3 158.8 61.9 13.5 8.3 56.9 32.6 59.1 24.9 39.8 95.4 43.8 56.9 6.5 34.6 311.5 39.1 12.1 12.2 32.2 33.1 115.5 34.8 39.6 80.3 204.4 59.4 28.9 26.3 32.5 40.1 85.6 49.9 123.8 51.9 38.2 43.7 148.4 63.6 28.3 ALDOA ENSG00000149925 "Aldolase, fructose-bisphosphate A" P04075 16 30064164-30070457 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease variant, Glycogen storage disease, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 26754.8;tongue: 9180.4" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 3267.9;Extravillous trophoblasts: 2322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004177, CAB006252" Supported Approved Cytosol NA NA 640000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB006252: AB_437007, HPA004177: AB_1078128" "unprognostic (2.63e-2)" "unprognostic (3.22e-2)" "unprognostic (6.80e-2)" "unprognostic (1.33e-1)" "unprognostic (6.74e-3)" "unprognostic (4.28e-3)" "prognostic unfavorable (5.79e-5)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.68e-1)" "unprognostic (1.81e-1)" "unprognostic (2.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.19e-3)" "unprognostic (4.48e-2)" 569.3 696.4 616.8 443.1 697.4 732.5 512.6 617.3 719.7 566.0 617.0 774.1 517.9 533.7 201.0 1302.0 449.7 420.5 2286.1 731.9 652.0 709.0 217.1 425.6 358.2 762.3 654.0 510.4 390.5 943.1 525.1 351.4 763.9 457.7 400.1 465.2 904.9 597.6 26754.8 643.4 488.3 465.2 545.5 417.5 595.0 138.7 657.8 280.9 454.5 9180.4 478.3 761.8 740.3 558.7 2206.1 1620.4 477.9 1542.8 714.6 808.5 1520.8 1297.9 1336.2 1291.6 1603.0 1158.1 1643.6 1487.6 2072.2 1318.6 708.6 1632.6 966.8 2829.1 939.3 658.5 1272.9 1219.3 1202.7 2591.1 1112.5 1793.8 1251.3 1115.7 979.6 1455.4 968.9 2119.7 965.4 686.9 1070.0 951.1 1393.4 3136.7 1100.2 1477.0 1192.8 848.1 1346.6 1613.9 765.2 3353.2 1629.4 1230.5 950.7 668.5 808.6 3368.5 1213.9 591.2 1433.0 1194.7 1162.5 1892.3 750.3 1046.7 1430.0 1861.5 1387.3 1369.3 3524.5 1715.9 1532.9 2050.6 2694.7 2081.7 1008.7 2466.5 1138.1 908.5 1091.7 1047.0 2182.7 877.9 1027.4 996.9 2531.7 819.9 2780.2 824.0 1476.3 4372.2 616.8 697.4 617.3 719.7 731.9 652.0 762.3 654.0 763.9 545.5 657.8 558.7 17.0 12.8 32.4 83.2 281.2 792.0 716.4 3267.9 784.8 387.4 34.4 21.6 1968.4 273.1 1385.1 42.3 118.9 1194.1 107.9 1834.8 111.6 120.9 258.8 15.8 11.8 261.1 323.9 215.8 66.2 76.2 2322.1 329.7 513.3 16.1 196.5 18.7 289.5 102.0 1181.9 733.6 70.0 755.1 1265.4 632.2 715.4 1152.4 380.8 388.8 924.9 50.6 417.7 662.1 328.5 40.2 60.8 126.2 1497.1 405.1 409.4 676.9 1755.7 75.8 700.9 298.9 486.4 680.9 572.9 25.8 123.6 1174.6 684.5 1361.3 294.3 15.2 937.7 1146.2 ALG1 "CDG1K, HMAT1, HMT-1, Mat-1" ENSG00000033011 "ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase" Q9BT22 16 5033923-5087379 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060392 Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA060392: AB_2684273" "unprognostic (1.66e-2)" "unprognostic (5.18e-1)" "prognostic favorable (5.79e-4)" "unprognostic (1.55e-2)" "unprognostic (2.10e-2)" "unprognostic (3.22e-2)" "unprognostic (2.84e-2)" "unprognostic (2.52e-1)" "unprognostic (1.18e-2)" "unprognostic (1.17e-1)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (5.27e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (2.58e-3)" "unprognostic (3.86e-2)" 11.3 19.6 6.2 12.8 6.6 7.7 9.9 6.1 7.9 12.4 12.7 18.8 15.8 11.0 14.5 11.2 12.4 9.8 8.3 6.5 6.6 12.6 21.0 9.3 12.4 6.3 6.0 8.8 26.8 17.5 10.9 9.5 6.9 10.5 16.3 6.8 18.8 10.6 7.4 8.8 13.1 12.0 5.8 15.0 19.6 20.8 6.5 12.0 11.6 5.5 12.1 12.4 8.3 6.8 24.0 53.7 10.8 25.5 40.7 24.2 26.4 50.6 50.6 46.9 46.4 44.8 72.4 44.4 43.1 48.0 20.7 58.2 30.1 36.2 31.6 42.0 43.3 20.7 40.1 87.1 33.4 37.6 37.3 29.7 26.9 36.2 23.0 18.5 28.7 32.2 29.5 44.7 34.5 50.1 28.9 40.7 51.2 31.7 33.6 48.8 16.0 124.9 28.3 18.7 20.7 21.7 49.3 67.8 27.4 14.3 45.1 29.2 29.8 22.5 25.6 134.7 40.1 39.8 59.3 30.2 20.5 39.8 38.1 11.5 79.9 28.8 87.2 80.6 77.1 72.9 74.9 86.3 86.7 73.9 66.7 75.0 4.3 79.8 80.0 75.6 81.1 126.6 6.2 6.6 6.1 7.9 6.5 6.6 6.3 6.0 6.9 5.8 6.5 6.8 4.6 16.0 6.1 4.2 11.2 2.4 3.4 15.7 5.2 7.4 6.8 6.0 0.7 8.6 14.3 7.3 12.5 16.2 7.2 8.5 3.9 19.5 10.7 5.4 8.1 8.7 13.3 12.0 4.0 28.3 18.7 9.3 13.7 5.5 1.3 8.1 8.6 17.7 21.7 3.3 4.6 21.0 8.2 10.6 2.4 25.5 9.6 7.6 10.6 1.0 9.3 7.5 9.2 3.5 3.4 21.6 11.1 6.8 22.7 4.5 11.8 10.4 11.7 6.3 6.6 5.4 7.1 28.0 16.0 7.7 1.6 8.5 8.6 13.8 18.0 4.4 ALG13 "CDG1S, CXorf45, FLJ23018, GLT28D1, MDS031, TDRD13, YGL047W" ENSG00000101901 "ALG13 UDP-N-acetylglucosaminyltransferase subunit" Q9NP73 X 111665811-111760649 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Glycosyltransferase, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002853, HPA005498" Approved Approved Vesicles,Cytosol NA NA 11000000 "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Vesicles Cytosol "HPA002853: AB_1078131, HPA005498: " "unprognostic (4.13e-1)" "unprognostic (1.80e-1)" "unprognostic (2.45e-2)" "unprognostic (1.51e-1)" "unprognostic (6.97e-2)" "unprognostic (6.14e-2)" "unprognostic (2.74e-1)" "unprognostic (6.55e-3)" "unprognostic (2.26e-2)" "unprognostic (3.39e-3)" "unprognostic (1.73e-2)" "unprognostic (4.62e-3)" "prognostic unfavorable (1.10e-6)" "unprognostic (1.19e-1)" "unprognostic (1.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.45e-2)" 15.1 17.9 10.5 18.8 11.7 16.6 18.3 11.5 19.0 17.2 12.3 18.2 13.7 16.1 20.5 14.7 15.4 16.4 13.2 10.2 13.8 21.0 23.8 13.8 23.4 12.6 12.1 15.8 14.7 23.4 17.9 14.1 13.3 17.7 19.4 11.8 15.6 13.4 9.2 19.4 17.3 17.5 11.4 18.5 15.5 17.4 11.8 17.3 18.2 9.9 20.1 21.3 14.7 16.6 22.3 24.4 21.8 13.8 13.8 19.6 12.3 17.7 18.3 22.4 27.5 24.9 23.1 19.5 33.0 24.7 46.5 12.6 26.1 12.5 23.5 14.4 17.6 10.7 26.1 28.4 20.3 19.5 40.5 23.6 22.8 18.0 38.6 23.3 24.8 21.8 23.9 53.5 22.5 55.8 16.4 17.6 19.9 66.3 33.6 12.8 13.9 26.7 36.6 34.0 13.1 19.1 25.2 15.2 16.3 21.7 13.6 18.5 16.7 19.2 9.7 24.9 34.4 25.8 47.1 31.5 20.5 25.5 15.2 39.5 15.8 16.6 9.5 16.3 9.3 10.6 10.6 9.2 18.5 12.1 13.0 10.8 3.0 4.6 12.9 9.5 14.6 9.6 10.5 11.7 11.5 19.0 10.2 13.8 12.6 12.1 13.3 11.4 11.8 16.6 50.9 16.0 30.8 33.6 127.9 35.2 65.8 53.5 33.6 15.1 33.9 31.6 18.7 22.8 36.0 18.4 10.4 27.3 73.9 39.2 45.0 37.4 21.1 48.2 31.1 37.4 26.5 27.1 64.7 52.1 39.1 34.6 37.2 47.9 109.8 15.7 28.2 28.4 42.5 11.8 57.4 49.0 46.8 39.2 52.3 9.4 21.5 56.1 28.4 83.4 41.8 16.0 29.9 41.7 77.5 58.0 55.6 16.1 60.4 46.9 38.5 55.5 35.3 16.5 26.3 38.7 46.2 32.6 22.4 26.5 35.4 48.7 71.1 28.8 32.8 64.6 ALG5 bA421P11.2 ENSG00000120697 "ALG5 dolichyl-phosphate beta-glucosyltransferase" Q9Y673 13 36949738-37000763 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007989 Approved Approved Cytosol No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA007989: AB_1078132" "unprognostic (1.87e-1)" "unprognostic (1.73e-2)" "unprognostic (6.07e-2)" "unprognostic (1.05e-3)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.57e-2)" "unprognostic (5.82e-2)" "unprognostic (5.21e-2)" "unprognostic (7.46e-2)" "unprognostic (3.51e-2)" "unprognostic (3.30e-1)" "prognostic favorable (1.40e-5)" "unprognostic (7.44e-2)" "unprognostic (1.66e-1)" "unprognostic (7.14e-3)" "unprognostic (1.86e-1)" 29.1 32.3 12.1 19.6 13.3 26.9 41.6 13.4 25.7 34.2 14.9 36.0 27.1 23.5 77.9 21.7 23.3 23.2 18.5 12.4 13.7 41.2 61.9 24.5 20.7 13.5 13.1 20.6 90.1 40.2 18.7 25.4 14.0 26.5 46.4 11.2 51.9 30.9 18.5 20.9 27.6 23.4 13.6 23.6 36.6 15.2 12.6 22.7 54.9 10.5 28.9 30.5 21.6 14.8 24.3 35.0 31.5 29.4 95.1 61.8 22.5 63.9 81.1 63.7 53.7 71.0 84.1 35.2 25.9 45.7 55.0 57.5 41.9 55.0 62.6 37.4 77.7 77.2 27.5 40.1 85.1 69.6 43.7 62.7 88.8 49.4 60.6 41.5 47.7 43.9 39.8 49.7 59.9 45.6 47.4 59.8 29.1 188.2 27.5 54.3 30.4 102.5 71.5 49.8 25.2 45.5 29.2 62.8 34.2 25.4 34.4 79.1 36.1 32.7 20.4 37.2 45.8 35.8 28.8 37.4 51.2 41.9 57.1 59.1 55.7 26.2 53.4 62.3 54.4 44.1 49.1 55.6 57.1 40.2 46.4 47.2 5.8 54.7 53.0 109.0 65.7 69.2 12.1 13.3 13.4 25.7 12.4 13.7 13.5 13.1 14.0 13.6 12.6 14.8 52.0 51.3 51.9 11.1 51.5 34.7 45.9 142.9 27.3 19.8 50.2 42.5 14.2 61.5 86.0 53.3 10.4 81.4 49.4 28.9 23.5 93.5 33.7 31.5 44.1 45.5 36.1 25.9 19.5 140.2 74.4 46.0 32.1 40.1 29.2 25.9 37.9 77.3 69.7 11.8 22.4 76.3 111.9 37.1 52.1 25.8 40.0 39.4 80.0 14.0 45.2 36.6 25.7 18.1 30.6 85.9 50.9 38.4 166.6 56.4 51.4 62.7 43.8 25.2 46.0 34.4 70.7 57.6 23.7 33.6 30.3 81.3 43.0 58.5 62.2 50.7 ALG9 DIBD1 ENSG00000086848 "ALG9 alpha-1,2-mannosyltransferase" Q9H6U8 11 111782195-111871581 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 26.6;Inhibitory neurons: 31.8;Oligodendrocytes: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA038575 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" "HPA038575: AB_10672718" "unprognostic (1.48e-1)" "unprognostic (5.39e-2)" "unprognostic (6.22e-2)" "unprognostic (5.34e-3)" "unprognostic (8.72e-2)" "unprognostic (2.90e-1)" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (7.07e-3)" "unprognostic (5.11e-2)" "unprognostic (8.75e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (7.29e-5)" "unprognostic (9.15e-2)" "unprognostic (7.76e-2)" "unprognostic (4.20e-2)" "unprognostic (1.10e-2)" 14.0 9.7 6.3 8.6 7.1 7.8 12.4 8.2 7.8 12.9 6.3 10.9 12.1 11.5 10.9 11.4 9.2 7.9 10.1 6.3 6.6 9.5 13.4 9.6 6.6 6.5 6.8 12.5 19.7 12.7 10.0 9.6 6.7 9.6 10.3 12.0 17.5 11.3 9.1 15.2 10.2 11.1 5.6 8.4 12.0 13.6 6.1 9.8 12.3 8.3 9.2 11.3 11.1 6.4 16.6 16.5 30.7 31.1 19.0 18.0 23.7 20.5 16.5 16.4 17.9 28.7 27.4 27.1 28.7 23.8 21.4 29.8 16.6 25.4 23.4 20.2 12.2 19.7 8.6 21.2 22.0 22.2 13.6 15.5 17.2 17.7 17.8 24.2 16.2 20.2 20.3 41.0 28.4 12.5 22.2 20.3 10.7 23.3 15.9 20.4 26.9 51.5 18.5 13.7 15.0 25.4 18.0 28.0 11.4 21.6 29.0 9.3 16.9 35.0 25.2 17.1 22.6 13.3 10.2 24.4 15.1 27.4 24.7 4.5 3.1 3.8 4.0 4.5 4.7 4.0 4.1 4.6 5.2 3.1 5.8 3.6 1.1 4.2 4.0 5.6 4.5 3.3 6.3 7.1 8.2 7.8 6.3 6.6 6.5 6.8 6.7 5.6 6.1 6.4 3.2 0.0 4.4 21.5 5.9 2.0 1.5 3.2 9.6 8.9 3.8 3.4 5.6 1.5 3.9 7.3 8.4 3.5 4.6 3.2 3.9 7.5 5.1 2.0 5.2 4.1 4.2 6.3 26.6 7.1 12.6 4.7 4.6 3.8 0.0 5.5 2.2 6.8 3.2 15.2 31.8 4.0 4.1 1.9 1.9 4.3 4.7 3.5 0.0 12.2 3.1 4.9 3.1 21.1 31.8 6.5 2.9 3.8 22.8 1.3 4.6 2.3 2.2 9.7 6.6 3.5 5.4 4.2 5.7 8.6 1.6 9.0 5.8 2.5 4.4 0.8 ALKAL1 "AUGB, FAM150A, UNQ9433" ENSG00000196711 "ALK and LTK ligand 1" Q6UXT8 8 52534037-52565430 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.4;thyroid gland: 2.4" "Cell type enriched" "Detected in some" 4 "Distal tubular cells: 5.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CAPAN-2: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027368 Uncertain "Secreted - unknown location" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "HPA027368: AB_10602317" "unprognostic (1.18e-1)" "unprognostic (1.13e-4)" "unprognostic (9.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.52e-1)" "unprognostic (6.60e-2)" "unprognostic (1.70e-4)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (9.58e-3)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 1.2 0.0 1.1 0.6 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.5 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.8 0.0 0.0 0.0 0.5 0.7 0.2 0.0 0.4 0.1 0.1 0.0 2.4 0.0 0.0 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.5 0.1 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 5.9 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALKAL2 "AUGA, FAM150B" ENSG00000189292 "ALK and LTK ligand 2" Q6UX46 2 279558-288851 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 205.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 20.3;Ductal cells: 37.0;Endometrial ciliated cells: 24.0;Glandular and luminal cells: 50.3;Granulosa cells: 64.3;Proximal tubular cells: 28.1" "Cancer enhanced" "Detected in many" "renal cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "AF22: 138.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "amygdala: 4.3;basal ganglia: 3.0;cerebral cortex: 2.5;hippocampal formation: 3.4;spinal cord: 2.3" "Secreted - unknown location" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.39e-3)" "unprognostic (1.44e-2)" "unprognostic (2.41e-2)" "unprognostic (2.03e-3)" "unprognostic (2.88e-1)" "unprognostic (3.73e-2)" "unprognostic (1.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.07e-1)" "unprognostic (7.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.35e-1)" "unprognostic (9.29e-3)" "unprognostic (5.19e-2)" "unprognostic (3.68e-1)" 28.8 205.4 4.6 2.0 6.3 0.6 26.6 3.5 2.9 4.9 4.8 8.2 3.7 26.4 13.4 2.0 26.2 10.7 2.2 3.1 5.4 21.1 4.5 34.0 0.9 3.6 2.1 74.4 64.3 2.3 8.6 9.6 2.7 6.5 6.5 0.4 5.4 2.6 1.5 17.3 7.7 9.9 1.8 12.3 17.3 35.5 5.1 1.7 10.4 0.5 1.6 4.7 5.3 4.8 0.0 0.0 138.8 0.1 0.8 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.4 1.3 0.0 0.0 0.2 0.5 0.0 0.0 0.5 0.3 0.0 0.1 0.7 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.2 2.4 0.0 0.0 6.8 0.4 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.1 0.1 0.2 0.2 0.3 0.7 0.1 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.2 0.1 4.6 6.3 3.5 2.9 3.1 5.4 3.6 2.1 2.7 1.8 5.1 4.8 2.5 0.0 11.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 14.6 20.3 0.0 0.0 0.0 1.8 0.0 0.1 1.4 0.0 3.9 37.0 0.0 24.0 6.3 4.5 0.0 0.0 0.0 0.7 0.1 3.1 0.0 50.3 0.0 64.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.1 0.6 0.9 0.0 0.0 ALKBH1 "ABH, alkB, ALKBH, hABH" ENSG00000100601 "AlkB homolog 1, histone H2A dioxygenase" Q13686 14 77672404-77708023 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, RNA repair, Translation regulation" "Dioxygenase, Lyase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044087, HPA060061" Approved Supported "Nucleoplasm,Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Endoplasmic reticulum" "HPA044087: AB_2678803, HPA060061: " "unprognostic (1.92e-2)" "unprognostic (8.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.37e-3)" "unprognostic (3.41e-2)" "unprognostic (5.03e-2)" "unprognostic (3.74e-3)" "unprognostic (7.45e-3)" "unprognostic (2.68e-2)" "unprognostic (3.95e-2)" "unprognostic (5.05e-3)" "unprognostic (2.16e-2)" "prognostic favorable (1.80e-4)" "unprognostic (1.65e-3)" "unprognostic (1.46e-1)" "unprognostic (2.63e-1)" "unprognostic (2.44e-2)" 2.7 2.7 2.8 1.8 3.2 1.2 3.5 3.9 3.5 3.4 2.7 2.8 2.5 2.3 2.1 2.6 2.9 2.2 4.1 3.0 3.5 3.0 3.6 2.2 3.5 2.8 3.2 2.9 2.6 3.3 1.5 3.9 2.9 3.1 3.4 2.9 2.1 3.1 5.7 2.6 2.1 2.9 3.0 2.3 2.5 3.0 3.2 4.4 3.1 7.4 4.1 3.1 2.2 3.3 5.2 7.5 6.0 4.1 6.3 6.8 7.4 5.3 6.8 11.3 12.7 7.7 3.1 7.9 2.9 4.8 5.3 4.5 13.2 5.7 13.2 5.4 5.1 4.2 4.0 6.4 8.9 4.5 2.6 5.8 9.2 6.6 10.5 5.0 9.4 6.1 6.6 4.4 6.1 8.1 6.0 5.7 6.6 7.7 9.6 6.0 6.0 5.3 6.4 4.5 7.6 5.7 4.3 4.5 5.7 4.9 10.9 4.5 4.3 4.7 4.7 5.2 4.3 5.4 9.4 7.6 3.2 6.3 4.7 10.7 3.0 1.4 2.9 3.5 2.4 3.4 2.7 2.8 3.0 2.7 2.8 2.2 0.8 3.6 2.4 1.6 3.3 2.2 2.8 3.2 3.9 3.5 3.0 3.5 2.8 3.2 2.9 3.0 3.2 3.3 6.5 0.0 3.9 13.1 7.3 8.4 5.7 6.2 6.8 4.1 5.4 4.4 7.5 1.5 4.5 1.8 2.1 9.9 3.5 4.2 9.8 6.2 4.8 4.4 4.5 5.7 2.4 4.2 15.9 7.0 8.8 5.5 2.6 3.8 9.5 6.1 2.2 3.9 7.6 0.0 15.8 4.9 6.1 5.2 5.0 4.2 6.5 7.7 5.4 5.6 6.6 7.8 4.1 16.1 19.4 6.8 1.5 5.3 4.9 4.5 7.0 6.5 5.5 5.3 6.6 4.2 5.6 21.1 15.9 4.4 5.4 12.2 5.6 5.1 4.8 3.7 ALKBH5 "FLJ20308, OFOXD1" ENSG00000091542 "AlkB homolog 5, RNA demethylase" Q6P6C2 17 18183078-18209954 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 236.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007196 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA007196: AB_1850461" "unprognostic (1.07e-1)" "unprognostic (1.51e-1)" "unprognostic (2.23e-2)" "unprognostic (1.48e-2)" "unprognostic (1.80e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (2.64e-1)" "unprognostic (1.34e-1)" "unprognostic (1.94e-2)" "prognostic favorable (3.75e-4)" "unprognostic (6.54e-2)" "unprognostic (3.99e-2)" "unprognostic (2.88e-2)" "unprognostic (3.22e-2)" "unprognostic (4.68e-3)" "prognostic unfavorable (5.69e-4)" 33.4 40.1 23.7 21.4 21.8 32.6 29.2 18.1 23.5 34.2 17.8 51.1 22.3 45.3 5.2 25.9 43.1 21.6 68.6 20.4 23.4 29.9 33.6 28.8 25.1 23.2 23.7 33.5 36.0 26.6 39.8 17.4 29.5 31.7 10.6 26.5 36.4 25.1 236.6 28.1 31.0 22.0 19.3 26.8 33.6 51.3 26.7 22.2 29.8 98.7 15.8 43.0 29.6 27.4 90.3 86.4 27.8 47.0 37.0 25.0 30.1 41.1 41.8 56.8 51.5 96.1 19.9 53.9 65.4 35.9 29.4 56.2 40.9 33.6 26.8 71.3 74.0 35.4 47.7 41.8 32.5 27.4 53.0 24.3 23.1 41.8 24.7 33.9 31.8 35.3 45.0 20.4 29.8 60.6 60.1 28.6 24.9 28.3 44.4 57.6 56.0 89.0 14.4 31.0 32.5 47.6 44.8 27.2 41.7 90.9 31.4 20.9 38.3 55.8 44.1 87.8 78.0 32.0 25.1 32.2 100.6 38.8 39.0 3.6 7.4 20.4 13.0 7.8 11.9 6.8 13.3 16.1 9.0 10.0 9.5 9.5 4.3 7.2 11.6 5.7 7.4 6.7 23.7 21.8 18.1 23.5 20.4 23.4 23.2 23.7 29.5 19.3 26.7 27.4 37.2 35.3 33.3 17.9 41.1 64.6 29.0 26.8 19.4 80.3 48.7 40.3 93.5 28.6 24.4 27.6 39.6 33.0 59.0 44.9 84.1 27.4 58.9 53.9 36.5 36.6 60.9 24.0 17.0 31.4 44.8 42.4 18.3 36.7 40.7 25.2 35.7 65.2 33.5 119.5 18.1 45.0 22.4 45.3 56.9 42.5 41.0 36.4 49.8 7.5 36.3 76.3 57.7 9.0 24.0 32.8 38.7 51.9 21.1 35.3 47.6 115.2 46.4 58.9 19.7 39.4 47.3 118.7 117.3 20.3 56.0 31.5 48.3 32.7 39.1 28.6 ALPG "ALPPL2, GCAP" ENSG00000163286 "Alkaline phosphatase, germ cell" P10696 2 232406844-232410714 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "endometrial cancer: 49.1;testis cancer: 64.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 33.9;HaCaT: 24.9;SuSa: 38.3" "CAB020698, HPA038764, HPA038765, HPA051699" Approved Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB020698: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (1.39e-1)" "unprognostic (6.63e-3)" "unprognostic (1.27e-2)" "unprognostic (2.89e-1)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (1.69e-3)" "unprognostic (1.65e-1)" "unprognostic (2.67e-1)" "unprognostic (6.72e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.7 33.9 0.0 0.0 0.0 0.0 24.9 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.3 0.0 38.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ALPI IAP ENSG00000163295 "Alkaline phosphatase, intestinal" P09923 2 232456125-232460753 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 138 "intestine: 141.2" "Cell type enriched" "Detected in some" 8 "Proximal enterocytes: 290.1" "Cancer enhanced" "Detected in many" "liver cancer: 4.7;renal cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "CACO-2: 4.8" "HPA038764, HPA038765, HPA051699" Supported Approved "Plasma membrane" "Intracellular and membrane" NA NA 130000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (1.01e-1)" "unprognostic (7.71e-2)" "unprognostic (4.14e-2)" "unprognostic (1.47e-1)" "unprognostic (9.57e-4)" "unprognostic (8.07e-2)" "unprognostic (1.71e-1)" "unprognostic (9.99e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 141.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 128.1 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 33.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 290.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 ALPL "HOPS, TNALP, TNAP, TNSALP" ENSG00000162551 "Alkaline phosphatase, biomineralization associated" P05186 1 21509397-21578410 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 92.0;Breast myoepithelial cells: 32.4;Glandular and luminal cells: 43.3;Hepatic stellate cells: 40.7;Hepatocytes: 30.1;Proximal tubular cells: 43.9;Rod photoreceptor cells: 34.2" "Cancer enhanced" "Detected in all" "testis cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 90 "neutrophil: 379.1" "Lineage enriched" "Detected in many" 139 "granulocytes: 379.1" "Cell line enhanced" "Detected in many" "HSkMC: 176.9;hTEC/SVTERT24-B: 141.2;LHCN-M2: 103.7;NTERA-2: 41.2;SCLC-21H: 88.2;SuSa: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB020829: , HPA007105: AB_1078137, HPA008765: AB_1078138" "unprognostic (3.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (3.05e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.08e-4)" "unprognostic (1.17e-2)" "unprognostic (2.48e-3)" "unprognostic (1.74e-1)" "unprognostic (7.28e-2)" "unprognostic (1.73e-2)" "unprognostic (2.27e-1)" "unprognostic (9.70e-3)" "unprognostic (2.58e-1)" 24.7 60.7 19.5 27.9 16.7 4.2 22.9 18.0 25.8 3.4 26.0 5.0 2.6 5.8 1.3 4.1 10.4 3.9 16.4 17.8 18.8 45.7 56.3 54.9 6.4 21.7 17.7 2.8 3.9 3.3 9.3 3.1 22.4 7.1 1.5 18.8 6.4 9.2 1.1 4.2 7.5 3.5 18.2 45.5 4.7 4.2 21.3 1.5 8.6 5.7 5.9 9.7 3.3 17.3 0.0 0.2 5.2 0.2 0.8 6.6 11.4 0.4 2.4 0.9 1.5 1.0 0.0 2.4 7.7 0.0 0.1 0.1 31.3 0.2 0.6 0.0 2.1 0.0 3.5 3.9 1.8 0.0 0.7 176.9 0.0 141.2 0.5 0.0 0.0 0.0 0.2 0.0 103.7 0.0 0.1 0.0 41.2 0.2 0.0 0.0 3.8 0.2 0.1 0.0 88.2 1.2 0.0 0.1 0.3 48.1 0.2 0.0 0.0 5.2 4.3 0.1 0.0 0.3 0.0 0.1 0.9 0.0 0.8 0.0 0.0 4.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 379.1 0.0 0.0 0.0 0.0 0.1 19.5 16.7 18.0 25.8 17.8 18.8 21.7 17.7 22.4 18.2 21.3 17.3 25.9 3.2 92.0 0.3 3.8 0.1 0.6 8.2 0.6 2.5 6.6 32.4 2.1 2.8 17.6 0.0 0.0 0.1 0.1 0.0 7.9 0.0 1.4 15.0 2.2 26.5 0.0 5.7 0.9 0.0 0.3 6.8 0.0 43.3 7.6 10.6 40.7 30.1 0.1 1.7 0.3 0.0 12.2 1.6 0.3 8.5 0.3 1.0 0.0 18.7 0.0 6.0 0.0 6.0 0.2 0.0 0.0 0.0 0.3 1.7 0.0 43.9 3.6 34.2 0.0 0.3 5.1 0.4 14.0 0.2 0.4 1.5 1.0 8.0 0.0 0.3 ALPP "PALP, PLAP" ENSG00000163283 "Alkaline phosphatase, placental" P05187 2 232378724-232382889 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 17.8;placenta: 34.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 12.8;Glandular and luminal cells: 5.0;Syncytiotrophoblasts: 6.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 381.0;SiHa: 103.6" "CAB026327, HPA038764, HPA038765, HPA051699" Enhanced Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB026327: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (4.86e-2)" "unprognostic (5.19e-3)" "unprognostic (6.67e-3)" "unprognostic (2.60e-1)" "unprognostic (2.44e-3)" "unprognostic (1.26e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.44e-1)" "unprognostic (4.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 17.8 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 34.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.5 42.9 0.0 0.1 0.0 0.1 381.0 0.0 0.0 0.0 0.0 0.2 0.0 7.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 103.6 35.3 0.0 3.5 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 6.7 0.1 0.2 0.0 0.0 AMBN ENSG00000178522 Ameloblastin Q9NP70 4 70592256-70607288 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Microglial cells: 1.9" "Group enriched" "Detected in some" 7 "cervical cancer: 2.6;endometrial cancer: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HEK 293: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036099 Uncertain Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoplasm "HPA036099: " "unprognostic (3.22e-1)" 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.3 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AMBP "EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI" ENSG00000106927 "Alpha-1-microglobulin/bikunin precursor" P02760 9 114060127-114078328 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 10947.9" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 10517.4" "Cancer enriched" "Detected in many" 115 "liver cancer: 2620.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 173 "Hep G2: 1398.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001497, CAB069436, HPA075585" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" NA NA 47000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus, Cytosol" "CAB069436: AB_1611916, HPA001497: AB_1078144, HPA075585: " "unprognostic (6.92e-2)" "unprognostic (3.61e-1)" "unprognostic (4.95e-3)" "prognostic favorable (1.20e-4)" "unprognostic (9.79e-2)" "unprognostic (2.90e-1)" "unprognostic (1.04e-3)" "unprognostic (7.59e-2)" "unprognostic (2.83e-2)" "unprognostic (2.04e-1)" "unprognostic (2.14e-1)" "unprognostic (7.84e-2)" "unprognostic (4.36e-2)" "unprognostic (2.89e-3)" "unprognostic (4.66e-2)" "unprognostic (2.97e-3)" "unprognostic (9.45e-3)" 0.7 0.2 0.1 0.0 0.1 0.0 6.4 0.3 0.4 0.2 0.3 0.3 2.3 0.1 0.4 0.3 0.4 160.4 0.5 0.1 0.1 11.0 10947.9 0.3 0.0 0.1 0.1 0.2 125.3 0.0 0.2 0.4 0.1 0.2 0.5 0.2 0.1 0.0 0.2 0.3 0.7 0.0 0.1 3.1 2.6 1.0 0.1 0.1 0.4 0.0 0.2 0.1 0.2 0.0 0.0 6.7 0.1 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 1.8 0.0 1.8 2.1 0.2 0.9 0.5 0.0 0.0 0.0 3.2 0.0 3.0 1.0 1398.1 0.0 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.1 0.3 0.0 0.9 3.1 0.0 0.2 8.1 0.4 5.9 0.6 1.7 0.0 2.8 1.1 0.0 0.1 0.0 0.2 1.0 0.0 0.8 0.0 0.4 1.0 0.3 1.5 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.5 0.0 19.1 1.5 0.6 0.0 2.2 0.0 1.9 0.4 0.2 2585.0 0.6 1.8 0.0 0.1 0.0 0.6 3.9 216.5 30.4 0.2 0.1 10.0 2.4 219.2 0.1 28.2 0.8 0.1 0.0 1.0 0.0 0.0 181.3 10517.4 0.7 0.0 0.1 1.6 0.0 243.7 0.5 59.4 0.6 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 14.9 1.7 0.0 0.0 0.6 0.6 13.7 0.0 0.0 0.0 0.0 0.5 0.6 0.2 1.1 0.4 1.4 14.3 0.0 1.2 0.3 AMELX "AIH1, AMG" ENSG00000125363 "Amelogenin X-linked" Q99217 X 11293413-11300761 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "urothelial cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "unprognostic (1.76e-1)" "unprognostic (1.00e-1)" "unprognostic (2.00e-1)" 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.3 0.5 0.5 0.4 0.2 0.3 0.2 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 AMELY AMGL ENSG00000099721 "Amelogenin Y-linked" Q99218 Y 6865918-6911774 "Predicted secreted proteins" Biomineralization "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.62e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 AMH MIS ENSG00000104899 "Anti-Mullerian hormone" P03971 19 2249309-2252073 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Gonadal differentiation" "Growth factor" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 3.9;testis: 10.5" "Cell type enriched" "Detected in many" 61 "Granulosa cells: 1567.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 16.9;NTERA-2: 6.4;REH: 7.0;SH-SY5Y: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066973 Approved Vesicles,Aggresome "Secreted to blood" NA NA 1580000 280000 "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Aggresome" "HPA066973: AB_2732754" "unprognostic (8.10e-5)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.21e-5)" "unprognostic (8.73e-3)" "unprognostic (1.32e-1)" "unprognostic (1.32e-1)" "unprognostic (8.03e-2)" "unprognostic (8.99e-2)" "unprognostic (2.55e-1)" "unprognostic (3.53e-1)" "unprognostic (5.95e-3)" "unprognostic (1.34e-2)" "unprognostic (8.73e-8)" "unprognostic (4.64e-2)" "unprognostic (4.14e-2)" "unprognostic (2.15e-1)" "unprognostic (2.76e-1)" 0.2 0.2 0.7 0.0 1.2 0.0 0.2 1.2 1.3 0.4 0.0 0.8 0.0 0.3 0.0 0.3 0.4 0.0 0.2 0.2 0.4 0.5 0.3 0.3 0.0 0.4 0.5 1.1 1.2 0.0 3.9 0.0 0.4 0.5 0.0 0.0 0.2 0.0 1.5 0.2 0.4 0.0 0.6 0.2 0.2 10.5 0.6 0.0 0.3 0.0 0.0 0.2 0.3 0.4 2.8 0.2 0.1 0.4 0.0 0.0 4.3 0.6 0.0 0.0 0.0 0.1 0.2 0.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.0 16.9 0.1 0.8 0.0 0.0 0.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.6 0.4 0.0 0.5 0.1 1.3 6.4 0.0 1.5 7.0 1.4 0.9 0.0 0.2 0.4 7.7 0.1 0.0 1.7 0.0 0.8 0.0 0.7 0.6 1.3 0.9 2.5 4.7 3.7 0.8 0.3 1.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 1.2 1.3 0.2 0.4 0.4 0.5 0.4 0.6 0.6 0.4 0.3 0.0 0.0 2.0 0.0 0.1 0.2 0.1 0.6 12.1 1.6 2.2 1.1 1.5 0.0 0.0 2.1 0.3 0.4 1.1 0.0 0.3 2.0 0.7 0.8 0.5 1.2 0.4 1.6 0.2 0.3 0.4 0.0 1.5 0.0 1567.5 0.7 0.3 0.1 8.4 11.5 1.0 0.0 0.0 0.0 9.2 1.5 2.3 0.0 1.9 0.1 6.3 0.0 1.0 2.2 0.0 0.0 0.4 0.1 0.1 0.9 0.2 0.1 2.3 0.0 9.2 25.6 8.1 0.6 0.7 0.1 0.0 0.4 0.0 0.8 0.2 AMPD1 "MAD, MADA" ENSG00000116748 "Adenosine monophosphate deaminase 1" P23109 1 114673090-114695618 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 559.2;tongue: 211.4" "Group enriched" "Detected in some" 6 "Plasma cells: 43.8;Skeletal myocytes: 13.3" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 29 "U-266/70: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026478, HPA028080" Enhanced "Intracellular and membrane" NA NA 38000 "Cluster 37: B-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" "HPA026478: AB_10599969, HPA028080: AB_10600776" "unprognostic (1.98e-3)" "unprognostic (1.43e-3)" "unprognostic (8.75e-3)" "unprognostic (8.03e-2)" "unprognostic (1.95e-2)" "unprognostic (5.61e-3)" "unprognostic (8.21e-2)" "unprognostic (4.29e-3)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.36e-5)" "unprognostic (1.68e-1)" "unprognostic (3.70e-1)" "unprognostic (3.36e-1)" "unprognostic (4.02e-1)" 0.1 0.1 0.0 0.5 0.0 0.3 3.0 0.0 0.0 0.2 0.0 5.6 16.4 0.2 0.0 5.8 0.4 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.0 1.0 0.1 0.3 0.0 0.0 0.0 3.5 5.5 0.0 4.4 0.9 559.2 0.0 7.5 0.1 0.0 1.6 3.7 0.1 0.0 0.4 0.1 211.4 2.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.8 1.9 0.0 0.0 0.0 3.0 4.2 0.0 0.0 0.0 43.8 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 AMTN "RSTI689, UNQ689" ENSG00000187689 Amelotin Q6UX39 4 70518569-70532743 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 28.3;salivary gland: 6.8;stomach 1: 7.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 14.0;Ionocytes: 4.1" "Group enriched" "Detected in many" 11 "cervical cancer: 13.9;head and neck cancer: 38.3;lung cancer: 12.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 16.7;hTERT-RPE1: 23.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036136, HPA036137" Uncertain "Secreted in other tissues" NA NA "Cluster 16: Immune cells - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA036136: AB_2674963, HPA036137: AB_10673614" "unprognostic (1.72e-1)" "unprognostic (2.47e-1)" "unprognostic (2.04e-1)" "unprognostic (2.36e-1)" "unprognostic (3.80e-1)" "unprognostic (1.52e-1)" "unprognostic (1.86e-2)" "unprognostic (7.35e-2)" "unprognostic (2.55e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 6.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.3 0.0 0.1 0.3 0.0 0.0 28.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.7 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.5 23.7 0.1 0.0 0.1 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.5 14.0 0.0 0.0 0.1 0.3 0.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 1.3 0.0 0.0 0.9 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 AMY1A AMY1 ENSG00000237763 "Amylase alpha 1A" P04745 1 103655290-103664554 "Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 290 "salivary gland: 22089.3" "Cell type enriched" "Detected in some" 6 "Respiratory ciliated cells: 21.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004310, HPA045394, HPA045399, HPA046980" Enhanced "Secreted to digestive system" NA NA 70000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 49: Ciliated cells - Cilium organization" "CAB004310: AB_626668, HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" 0.0 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.0 76.1 0.0 0.0 0.0 0.0 0.0 0.0 27.6 0.0 0.7 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.8 6.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 22089.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.5 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.2 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 21.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 AMY1B AMY1 ENSG00000174876 "Amylase alpha 1B" P04745 1 103687415-103696680 "Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "salivary gland: 4607.5" "Cell type enriched" "Detected in some" 5 "Respiratory ciliated cells: 19.1" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 70000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 49: Ciliated cells - Cilium organization" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (7.34e-2)" "unprognostic (2.59e-1)" "unprognostic (6.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.96e-1)" 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 86.5 0.0 0.0 0.0 0.1 0.0 0.6 56.3 0.0 0.9 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.4 32.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4607.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.6 1.3 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.8 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 19.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 AMY1C AMY1 ENSG00000187733 "Amylase alpha 1C" P04745 1 103750406-103758690 "Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "pancreas: 125.9;salivary gland: 199.3" "Group enriched" "Detected in some" 7 "Alveolar cells type 2: 36.2;Respiratory ciliated cells: 51.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 70000000 "Cluster 25: Pancreas - Digestion" "Cluster 49: Ciliated cells - Cilium organization" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.1 0.0 0.0 13.3 0.0 0.0 0.0 0.3 125.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 199.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.8 0.0 4.6 10.8 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 AMY2A AMY2 ENSG00000243480 "Amylase alpha 2A" P04746 1 103616811-103625780 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1983 "pancreas: 148689.6" "Cell type enriched" "Detected in some" 114 "Exocrine glandular cells: 1016.0" "Cancer enriched" "Detected in single" 2010 "pancreatic cancer: 200.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045394, HPA045399, CAB045960, HPA046980" Enhanced "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" "CAB045960: AB_2226891, HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (3.27e-1)" "unprognostic (1.78e-3)" "unprognostic (3.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.13e-2)" 6.0 1.3 1.2 2.8 1.3 0.3 3.9 0.7 1.4 3.3 0.6 1.7 22.5 2.9 0.1 2.3 0.8 0.0 26.6 1.2 0.9 1.5 4.7 1.0 5.4 0.8 0.9 74.9 148689.6 0.1 1.5 8.3 0.8 2.1 0.0 0.6 30.0 0.0 1.5 1.4 10.7 0.0 0.7 1.7 2.2 1.2 0.9 0.0 1.1 0.0 0.0 0.5 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.7 1.4 1.2 0.9 0.8 0.9 0.8 0.7 0.9 1.0 0.1 0.0 0.0 2.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.1 0.0 0.0 0.2 0.0 0.0 1.3 1016.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 4.6 0.0 0.0 0.0 0.1 8.9 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.2 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.6 AMY2B AMY2 ENSG00000240038 "Amylase alpha 2B" P19961 1 103553815-103579534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 122 "pancreas: 31246.7" "Cell type enhanced" "Detected in many" "Astrocytes: 56.2;Excitatory neurons: 61.2;Exocrine glandular cells: 148.0;Inhibitory neurons: 48.4;Oligodendrocytes: 41.8" "Cancer enriched" "Detected in many" 15 "pancreatic cancer: 25.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 5.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.8;EFO-21: 10.3" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 77000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (8.69e-4)" "unprognostic (3.71e-3)" "unprognostic (6.41e-2)" "unprognostic (9.75e-2)" "unprognostic (1.32e-1)" "unprognostic (1.51e-4)" "unprognostic (1.21e-2)" "unprognostic (1.63e-2)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-2)" "unprognostic (7.41e-3)" "unprognostic (1.55e-2)" "unprognostic (5.74e-2)" "unprognostic (4.22e-1)" "unprognostic (3.12e-4)" 35.4 24.8 29.5 11.2 34.8 13.4 34.9 39.9 38.6 40.8 19.7 33.0 16.5 22.7 20.2 13.1 50.3 14.1 40.9 27.9 29.5 59.4 39.0 30.2 20.0 27.7 29.1 40.0 31246.7 14.9 36.8 6.9 27.1 35.3 11.9 69.8 256.2 14.6 63.7 42.6 31.7 9.8 26.3 34.8 18.1 5.2 30.6 12.6 63.5 25.2 13.8 29.3 25.8 30.0 0.0 0.5 1.1 0.0 5.6 9.8 1.1 0.8 0.8 0.6 1.5 0.0 0.2 1.0 10.3 0.3 0.0 1.2 0.1 1.3 1.4 1.3 1.6 1.9 4.5 0.8 0.8 2.5 2.6 6.7 6.7 0.8 1.2 1.8 0.2 3.0 0.0 3.2 0.9 0.0 1.9 0.5 0.1 0.1 1.4 0.5 0.0 4.7 5.7 2.0 2.8 0.6 2.4 1.1 0.8 1.8 0.1 1.4 0.8 0.3 0.9 0.5 0.7 3.5 0.1 0.3 1.9 1.8 0.2 0.0 5.0 1.0 0.4 2.5 0.3 1.0 0.1 0.2 1.6 0.9 0.6 0.2 1.2 0.1 2.2 0.5 0.2 1.2 29.5 34.8 39.9 38.6 27.9 29.5 27.7 29.1 27.1 26.3 30.6 30.0 2.8 12.8 20.1 56.2 3.2 4.7 4.2 1.4 0.6 11.7 2.9 2.7 7.2 2.8 11.2 1.8 33.3 0.4 2.4 3.6 0.0 1.3 7.3 1.1 0.6 2.7 4.9 1.3 61.2 148.0 0.4 3.2 2.0 0.7 3.8 0.5 2.2 6.5 1.6 10.1 48.4 2.5 0.0 9.4 3.5 2.7 2.5 3.4 5.4 11.2 4.0 3.1 2.1 22.1 41.8 1.3 2.7 1.9 1.4 1.5 4.3 0.8 14.6 15.4 0.0 1.0 2.5 1.5 0.9 0.4 3.0 0.3 1.7 0.4 2.2 1.6 ANAPC11 "APC11, Apc11p, HSPC214, MGC882" ENSG00000141552 "Anaphase promoting complex subunit 11" Q9NYG5 17 81890790-81900991 "Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1161.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA021989, HPA027838" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Nucleoli "HPA021989: AB_1844915, HPA027838: AB_10600978" "unprognostic (9.00e-3)" "unprognostic (1.24e-2)" "unprognostic (3.76e-1)" "unprognostic (4.93e-2)" "unprognostic (8.76e-2)" "unprognostic (1.67e-1)" "unprognostic (5.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.65e-1)" "unprognostic (2.17e-3)" "unprognostic (2.22e-2)" "unprognostic (1.08e-1)" "unprognostic (4.76e-2)" "unprognostic (8.07e-2)" "unprognostic (9.08e-2)" "unprognostic (2.51e-2)" "unprognostic (3.16e-1)" 112.1 120.5 104.8 52.1 108.6 109.3 103.4 110.9 149.5 85.9 100.7 126.0 61.0 86.4 39.0 125.8 80.3 58.0 231.3 106.4 106.8 127.3 185.7 89.3 73.0 110.0 105.1 76.4 108.1 59.0 92.0 54.8 105.0 105.7 27.3 19.3 117.6 42.0 272.8 99.7 83.4 36.5 110.4 86.7 117.9 189.7 113.0 50.1 90.6 126.5 34.0 95.9 94.7 118.1 262.4 605.0 139.0 209.7 118.7 132.8 164.3 123.4 100.6 111.4 127.1 248.6 226.9 82.1 133.3 114.4 121.8 148.9 58.1 166.4 40.5 122.5 437.1 126.8 257.9 379.0 131.3 95.3 103.6 145.6 151.8 120.4 98.2 73.4 184.9 111.9 173.7 233.8 120.8 474.1 225.5 150.6 131.2 259.2 448.7 92.3 136.2 168.0 104.9 229.3 175.8 282.6 133.5 205.7 253.8 96.7 254.1 222.7 108.4 215.0 169.5 229.4 234.1 110.5 52.1 107.0 228.7 144.5 177.7 495.1 419.8 418.8 229.7 359.9 218.7 309.0 232.0 252.9 348.0 296.2 223.0 212.3 212.1 258.5 345.4 581.1 297.9 506.0 104.8 108.6 110.9 149.5 106.4 106.8 110.0 105.1 105.0 110.4 113.0 118.1 137.2 128.2 157.2 11.4 110.5 148.6 215.0 406.1 145.7 59.5 272.5 332.7 360.2 201.6 272.3 198.6 20.9 467.8 119.5 239.6 522.3 260.6 451.9 157.0 151.3 152.9 190.3 201.6 9.8 337.7 524.6 182.9 124.4 169.5 108.3 158.3 159.2 496.4 448.2 33.7 10.2 272.6 319.4 174.6 194.3 1161.0 181.7 170.1 261.5 13.1 251.4 227.7 176.1 7.1 17.0 324.3 274.0 164.7 226.8 334.2 290.7 548.0 199.8 78.9 105.2 115.9 245.0 435.8 252.5 257.4 186.7 508.7 117.3 156.0 271.4 307.0 ANAPC2 "APC2, KIAA1406" ENSG00000176248 "Anaphase promoting complex subunit 2" Q9UJX6 9 137174784-137188560 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 58.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018692, HPA066539" Enhanced Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB018692: AB_2258285, HPA066539: AB_2685688" "unprognostic (5.20e-2)" "unprognostic (8.86e-3)" "unprognostic (1.43e-2)" "prognostic favorable (8.91e-5)" "unprognostic (2.29e-1)" "unprognostic (2.38e-2)" "unprognostic (4.46e-1)" "unprognostic (4.84e-2)" "unprognostic (1.07e-1)" "unprognostic (3.36e-1)" "prognostic favorable (1.07e-7)" "unprognostic (7.41e-2)" "prognostic favorable (3.67e-4)" "prognostic favorable (2.87e-4)" "unprognostic (1.35e-1)" "unprognostic (8.46e-2)" "unprognostic (9.88e-2)" 14.4 17.7 8.8 11.3 9.6 15.0 15.8 8.9 13.4 15.2 8.6 14.4 11.9 15.8 3.1 15.8 14.7 8.6 15.6 9.7 8.1 14.2 20.2 13.1 14.5 11.5 9.1 15.2 20.7 7.4 13.8 7.2 10.2 17.5 3.1 4.3 18.2 8.9 18.9 19.2 16.5 5.3 8.1 19.9 17.0 25.5 8.8 10.2 15.5 8.3 6.1 13.8 13.4 12.9 20.9 45.6 10.7 17.5 12.6 7.5 33.5 18.5 11.5 16.9 12.8 27.8 20.9 22.4 21.3 12.3 15.8 41.9 12.9 13.8 2.5 28.9 22.5 13.3 55.1 24.9 14.9 20.7 22.1 15.0 10.9 11.3 6.1 8.3 20.8 20.7 20.3 26.4 8.0 58.2 24.7 28.7 21.6 27.4 34.6 29.3 26.5 41.4 13.1 18.1 14.1 21.3 28.2 36.5 11.9 5.1 39.2 27.8 22.4 24.8 19.8 30.1 16.7 12.9 20.5 24.5 20.1 14.1 18.3 0.3 0.6 0.1 0.5 0.6 0.3 0.3 0.3 0.4 0.5 0.2 0.3 0.4 0.2 0.3 0.9 0.6 0.3 1.1 8.8 9.6 8.9 13.4 9.7 8.1 11.5 9.1 10.2 8.1 8.8 12.9 9.3 0.0 0.5 6.2 12.2 9.3 7.9 14.2 6.2 5.7 13.0 12.6 3.2 11.5 11.5 11.0 4.2 25.9 11.1 19.0 13.7 10.0 40.5 4.2 4.0 9.0 10.2 9.5 2.4 10.9 11.1 9.0 27.0 5.0 11.4 8.5 12.1 11.1 15.6 1.7 2.5 19.1 12.2 8.8 7.8 58.4 11.1 7.6 14.2 1.0 13.9 3.7 6.2 1.5 4.3 8.6 8.0 9.4 15.3 6.8 21.2 15.8 10.2 4.7 0.0 9.8 17.4 40.5 26.4 11.9 9.5 24.5 9.4 5.9 15.4 7.1 ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 3018.1" "Cell type enriched" "Detected in many" 24 "Hepatocytes: 4816.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.5;myeloid DC: 14.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Hep G2: 152.2;OE19: 116.1" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" Yes No 308000000 410000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" 37.6 3.0 3.6 6.0 3.5 1.0 37.8 3.5 4.9 38.2 5.6 32.6 23.2 23.4 17.9 9.8 30.5 28.5 16.9 3.6 4.9 18.4 3018.1 18.5 3.5 4.5 4.2 58.1 30.8 5.3 5.0 3.8 4.3 32.7 45.7 2.2 52.6 13.3 6.2 27.4 27.1 10.4 4.5 7.4 58.2 10.2 3.7 1.5 8.8 10.5 4.1 24.8 31.4 4.8 3.7 9.9 2.3 0.0 23.9 27.8 0.3 4.8 8.8 1.1 4.0 5.9 5.1 0.4 1.5 12.0 8.0 3.8 2.8 3.1 1.3 18.4 3.8 0.9 5.1 152.2 5.0 4.0 0.5 22.2 2.5 1.5 5.1 11.8 5.7 4.2 0.2 27.0 3.5 0.7 0.9 1.2 0.7 116.1 10.7 0.7 3.9 11.3 2.3 2.9 0.0 0.4 4.6 1.7 6.5 5.1 4.0 0.7 6.0 1.9 2.8 1.7 0.7 5.9 4.8 0.5 3.2 2.0 5.0 0.0 24.5 0.0 0.6 2.9 0.4 5.8 1.2 1.1 14.5 4.9 0.3 0.2 0.4 0.0 0.1 2.3 0.8 7.1 3.6 3.5 3.5 4.9 3.6 4.9 4.5 4.2 4.3 4.5 3.7 4.8 9.7 28.9 17.7 0.0 9.7 27.1 43.3 39.2 14.2 0.1 33.8 24.8 0.8 194.5 24.6 11.0 0.0 1.6 0.7 32.5 11.7 40.0 1.0 6.2 9.7 11.0 71.0 27.8 0.0 31.6 5.3 48.8 56.1 24.9 0.0 10.7 62.4 4816.3 15.9 0.0 0.0 171.9 12.2 95.9 18.7 2.9 71.1 13.8 23.2 0.0 4.9 10.1 0.0 0.0 0.0 21.6 33.3 24.0 11.7 43.7 91.3 61.2 76.5 0.6 13.1 29.7 17.7 1.0 1.3 9.4 52.4 9.3 5.6 0.5 51.6 39.2 ANGEL1 "Ccr4e, KIAA0759" ENSG00000013523 "Angel homolog 1" Q9UNK9 14 76786009-76826246 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 64.3;Late spermatids: 75.1;Oligodendrocyte precursor cells: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000948 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA000948: AB_2227189" "unprognostic (4.81e-2)" "unprognostic (2.37e-2)" "unprognostic (2.67e-1)" "unprognostic (2.46e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-1)" "unprognostic (7.33e-2)" "prognostic favorable (3.43e-4)" "unprognostic (9.24e-2)" "unprognostic (1.01e-1)" "prognostic favorable (5.46e-4)" "unprognostic (3.03e-1)" "unprognostic (6.92e-3)" "unprognostic (1.42e-1)" "unprognostic (2.22e-1)" "unprognostic (1.53e-1)" "unprognostic (6.32e-2)" 11.3 18.5 18.3 11.8 19.7 6.8 12.7 16.7 21.2 12.8 15.6 10.0 9.2 14.8 23.8 7.0 12.2 11.4 15.7 19.2 21.1 11.6 19.3 14.0 12.2 22.5 19.6 19.3 50.8 17.2 21.1 10.4 21.5 9.3 10.9 26.4 15.8 8.4 12.2 6.4 10.3 12.3 18.1 29.3 15.8 52.4 20.1 8.1 13.7 9.8 10.9 9.5 8.5 23.8 13.1 14.0 15.2 13.6 12.2 11.1 14.1 7.7 11.0 7.8 9.9 13.5 18.2 23.8 11.1 6.7 10.6 16.2 14.6 13.7 13.1 10.1 13.1 14.8 9.7 10.3 7.9 7.8 8.7 11.8 16.8 7.3 14.5 11.3 20.0 24.8 14.5 6.2 8.2 25.3 14.0 11.6 17.5 20.7 18.4 17.0 10.4 14.1 11.8 18.4 21.5 9.6 11.6 15.8 7.1 13.8 31.1 8.4 9.6 9.1 8.0 6.9 6.4 15.9 12.9 14.7 7.7 13.7 11.8 0.8 4.8 1.6 5.9 5.5 7.2 6.8 5.3 5.6 7.5 5.5 7.5 5.6 1.4 5.5 7.1 4.9 4.5 5.9 18.3 19.7 16.7 21.2 19.2 21.1 22.5 19.6 21.5 18.1 20.1 23.8 7.4 6.4 10.5 17.6 4.7 1.1 1.8 1.5 2.2 2.4 5.7 5.0 6.7 5.7 2.2 3.7 10.4 1.5 1.5 2.1 0.0 3.3 64.3 3.7 3.9 10.0 4.2 4.2 18.3 3.2 2.8 4.3 1.5 3.3 1.3 15.9 7.1 9.5 7.2 0.0 19.7 4.4 4.1 5.7 2.0 75.1 2.1 5.5 1.8 23.4 1.4 4.9 1.0 64.8 30.2 2.5 1.0 4.9 8.9 3.4 1.7 1.3 1.4 8.9 6.6 5.1 2.4 15.9 4.9 2.8 0.4 1.2 3.0 12.9 4.6 1.5 ANGPT1 "Ang1, KIAA0003" ENSG00000154188 "Angiopoietin 1" Q15389 8 107249482-107498055 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 33.5" "Group enriched" "Detected in many" 4 "Astrocytes: 60.4;Fibroblasts: 20.4;Inhibitory neurons: 37.6;Smooth muscle cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 5.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.8" "Cell line enhanced" "Detected in many" "ASC diff: 87.9;HEL: 53.1;HSkMC: 145.5;U-138 MG: 70.5;WM-115: 47.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017815, HPA018793, HPA018816" Approved "Secreted to blood" NA NA 32000000 110000 "Cluster 1: Neutrophils - Mixed function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB017815: , HPA018793: AB_1844820, HPA018816: AB_1844821" "unprognostic (7.71e-2)" "unprognostic (2.13e-1)" "unprognostic (6.37e-2)" "unprognostic (4.11e-3)" "unprognostic (7.36e-2)" "unprognostic (3.80e-2)" "unprognostic (2.22e-3)" "unprognostic (3.29e-2)" "unprognostic (1.07e-2)" "unprognostic (5.54e-2)" "unprognostic (2.62e-1)" "unprognostic (1.44e-1)" "prognostic favorable (4.40e-4)" "unprognostic (4.56e-3)" "unprognostic (1.69e-1)" "unprognostic (3.24e-1)" "unprognostic (1.76e-1)" 25.1 5.6 3.2 2.6 4.5 0.7 4.6 4.5 2.2 5.8 2.5 3.4 2.3 3.5 4.8 3.5 3.0 13.2 4.8 4.5 6.1 11.1 2.1 21.7 1.4 8.0 3.5 9.5 1.6 1.2 5.8 20.5 4.8 17.7 3.3 0.6 12.0 33.5 23.4 1.2 2.6 3.3 4.8 11.0 4.0 2.3 2.1 2.1 3.5 7.0 1.0 3.9 3.7 11.9 0.0 2.4 9.3 5.3 87.9 30.2 6.6 30.0 25.8 8.1 11.9 6.2 0.1 0.0 0.1 16.0 0.0 0.0 4.2 0.1 10.5 0.0 1.4 53.1 0.6 0.0 24.5 0.7 0.0 145.5 0.0 4.9 0.6 7.5 0.6 0.0 28.2 5.1 10.9 0.0 1.1 7.9 9.6 0.0 1.1 0.0 0.0 3.1 0.0 0.0 0.1 4.2 1.1 0.6 0.0 11.6 2.2 0.0 0.3 70.5 0.9 2.5 0.7 0.2 3.2 0.0 9.7 1.1 47.5 0.1 0.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.8 0.1 0.3 0.0 0.0 0.6 3.2 4.5 4.5 2.2 4.5 6.1 8.0 3.5 4.8 4.8 2.1 11.9 9.0 0.0 2.3 60.4 0.0 0.6 10.1 0.4 5.2 0.9 0.5 2.8 3.3 0.0 2.2 7.3 0.0 5.2 0.0 0.0 1.9 0.3 8.1 0.7 9.1 5.6 0.0 10.1 6.5 0.0 7.6 20.4 1.5 1.9 0.0 0.0 3.3 0.1 0.5 0.0 37.6 0.0 2.0 0.3 1.0 2.4 2.5 2.9 0.0 6.5 1.5 0.5 0.0 3.0 0.6 0.0 0.0 3.8 1.1 1.2 0.0 2.8 0.8 0.0 6.6 3.5 48.6 1.6 5.4 4.0 0.1 2.7 0.8 1.7 0.1 1.2 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANGPT4 ENSG00000101280 "Angiopoietin 4" Q9Y264 20 869900-916334 "Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 7.2;breast: 6.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 52.9;Late spermatids: 17.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 41 "ASC diff: 33.7;BEWO: 48.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013260, CAB013305" Uncertain "Secreted to blood" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB013260: , CAB013305: " "unprognostic (1.77e-1)" "unprognostic (3.25e-1)" "unprognostic (4.30e-2)" "unprognostic (1.04e-3)" "unprognostic (6.37e-2)" "unprognostic (3.41e-1)" "unprognostic (5.82e-4)" "unprognostic (1.25e-1)" "unprognostic (7.10e-2)" "unprognostic (3.66e-4)" "unprognostic (9.01e-2)" "unprognostic (1.71e-1)" "unprognostic (5.25e-2)" "unprognostic (1.23e-2)" "unprognostic (1.55e-1)" "unprognostic (2.95e-4)" "unprognostic (9.14e-2)" 7.2 0.3 0.3 0.1 0.3 0.0 6.6 0.2 0.3 3.8 0.1 0.3 0.1 3.3 2.1 0.2 3.3 0.3 0.2 0.2 0.4 0.2 0.2 1.2 0.1 0.3 0.3 3.9 0.1 0.1 0.0 0.0 0.4 0.5 0.1 0.1 0.3 0.4 0.0 1.4 0.3 1.1 0.2 0.0 0.3 0.6 0.4 0.2 1.7 0.6 0.0 1.0 2.2 0.3 0.2 0.0 0.0 0.0 33.7 0.0 48.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.3 0.2 0.4 0.3 0.3 0.4 0.2 0.4 0.3 0.3 0.0 0.5 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 52.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.3 17.0 1.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.9 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 ANGPTL1 "ANG3, ANGPT3, AngY, ARP1" ENSG00000116194 "Angiopoietin like 1" O95841 1 178849535-178871077 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 133.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 81.7;Leydig cells: 425.9;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "ASC diff: 149.9;ASC TERT1: 60.1;HHSteC: 64.9;HSkMC: 147.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009976 Approved "Secreted to blood" NA NA 380000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009976: AB_1844822" "unprognostic (2.59e-2)" "unprognostic (1.31e-1)" "unprognostic (5.80e-3)" "unprognostic (2.63e-2)" "unprognostic (3.60e-1)" "unprognostic (1.71e-2)" "prognostic favorable (8.73e-4)" "unprognostic (3.81e-2)" "unprognostic (5.78e-3)" "unprognostic (1.47e-1)" "unprognostic (1.39e-1)" "unprognostic (5.31e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.49e-2)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.61e-3)" 56.6 45.1 2.0 10.5 2.7 0.9 26.9 2.3 2.7 21.3 1.5 56.7 9.6 69.2 14.0 33.8 59.0 27.9 22.8 2.9 1.9 17.5 23.9 12.6 3.5 2.1 1.5 68.2 21.9 1.1 2.1 133.8 1.4 12.3 27.5 9.6 36.3 9.5 30.3 9.0 26.7 65.5 2.2 10.9 21.6 15.6 1.7 8.6 41.1 57.3 6.9 23.9 17.1 2.3 0.2 0.0 4.0 0.0 149.9 60.1 0.0 0.1 0.0 0.4 0.8 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 64.9 0.0 0.1 147.5 0.0 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.9 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.1 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 2.7 2.3 2.7 2.9 1.9 2.1 1.5 1.4 2.2 1.7 2.3 16.5 0.0 0.0 9.4 1.3 3.7 0.0 0.0 1.2 2.3 0.8 0.5 3.7 41.5 0.0 1.8 6.2 0.6 0.1 0.0 1.9 2.4 1.4 3.3 40.3 4.1 0.0 0.0 14.8 0.4 0.4 81.7 1.1 5.5 0.0 1.6 8.9 1.0 1.4 0.0 14.9 0.0 0.0 0.0 4.6 10.6 425.9 0.8 3.6 8.4 0.0 31.6 0.0 21.6 0.7 0.0 5.0 212.1 0.4 0.1 0.1 0.1 0.7 10.9 39.5 10.0 51.8 0.8 0.6 0.2 3.7 1.4 0.5 2.7 0.0 0.1 ANGPTL2 "ARP2, HARP" ENSG00000136859 "Angiopoietin like 2" Q9UKU9 9 127087348-127122635 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.4;Endothelial cells: 34.6;Fibroblasts: 99.7;Oligodendrocyte precursor cells: 35.2;Skeletal myocytes: 39.3;Smooth muscle cells: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 140.4;ASC TERT1: 94.9;BJ hTERT+: 205.9;HSkMC: 98.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040933, HPA041299" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 2510000 2200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA040933: AB_10795530, HPA041299: AB_10794552" "unprognostic (5.46e-2)" "unprognostic (4.96e-3)" "unprognostic (1.11e-2)" "unprognostic (2.07e-2)" "unprognostic (8.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.79e-2)" "unprognostic (2.04e-2)" "unprognostic (3.31e-1)" "unprognostic (1.17e-3)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (4.15e-2)" 109.5 11.5 6.1 33.5 12.9 0.2 71.2 15.1 8.6 67.7 12.4 76.5 15.1 72.9 13.7 21.7 31.4 67.0 69.2 6.9 9.4 13.4 14.8 22.5 8.1 12.0 12.4 44.2 5.5 4.1 3.4 21.4 11.7 24.7 17.9 0.9 18.0 27.1 57.6 29.2 27.8 63.4 9.9 49.2 28.9 4.4 12.6 4.7 15.7 36.6 8.9 59.4 49.1 15.4 0.0 0.0 17.4 0.0 140.4 94.9 9.4 8.1 205.9 9.2 8.5 0.0 0.0 0.0 7.0 21.4 1.8 0.1 1.7 0.0 4.8 0.1 0.0 0.0 0.1 0.5 30.3 0.1 0.0 98.2 0.0 20.0 0.0 28.7 27.6 2.3 0.0 0.1 6.3 0.0 0.2 4.3 18.4 0.0 1.0 16.5 27.3 1.6 2.2 0.0 9.3 10.1 0.0 0.0 0.0 3.3 0.0 0.0 8.8 35.5 4.5 50.4 0.0 0.0 0.1 0.0 37.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 12.9 15.1 8.6 6.9 9.4 12.0 12.4 11.7 9.9 12.6 15.4 47.4 9.6 2.4 1.0 0.1 14.3 7.0 0.2 3.4 14.4 0.6 6.6 16.6 0.0 0.1 0.0 2.1 1.0 0.5 0.1 0.0 0.2 1.6 1.4 20.2 34.6 0.0 0.0 0.6 0.0 0.8 99.7 1.1 1.0 0.0 2.9 5.0 0.0 1.4 0.0 1.5 0.0 0.0 0.0 17.4 1.5 20.8 0.8 7.2 1.9 0.0 1.9 0.0 35.2 19.2 1.2 0.0 6.4 0.0 1.7 0.0 2.4 1.6 0.8 0.0 39.3 43.5 1.0 0.0 1.4 11.1 2.6 1.7 1.1 0.0 0.6 ANGPTL3 ANGPT5 ENSG00000132855 "Angiopoietin like 3" Q9Y5C1 1 62597520-62606313 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Lipid metabolism" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 675.7" "Group enriched" "Detected in some" 12 "Hepatocytes: 567.6;Proximal tubular cells: 272.5" "Cancer enriched" "Detected in some" 39 "liver cancer: 94.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038097 Approved "Secreted to blood" NA NA 225000000 120000000 "Cluster 85: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038097: AB_10675628" "unprognostic (2.29e-1)" "unprognostic (8.01e-2)" "unprognostic (2.51e-1)" "unprognostic (4.06e-2)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (4.06e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-3)" "unprognostic (6.85e-3)" "unprognostic (2.89e-2)" "unprognostic (1.20e-2)" "unprognostic (1.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.09e-2)" "unprognostic (5.38e-2)" "unprognostic (7.62e-2)" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 53.0 675.7 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 4.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 11.5 0.0 5.5 0.0 0.0 0.0 0.0 33.2 0.0 0.0 0.1 0.1 0.7 0.0 16.0 0.1 0.2 0.1 0.0 2.6 0.3 0.0 0.0 9.7 567.6 0.1 0.0 0.1 0.0 0.0 16.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 272.5 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 0.0 ANGPTL4 "ARP4, FIAF, HFARP, NL2, PGAR, pp1158" ENSG00000167772 "Angiopoietin like 4" Q9BY76 19 8363289-8374370 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 195.8;breast: 165.0;liver: 183.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 318.9;Hepatocytes: 148.4;Pancreatic endocrine cells: 230.4;Proximal enterocytes: 146.3;Skeletal myocytes: 198.3" "Cancer enriched" "Detected in all" 4 "renal cancer: 212.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 3.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "ASC diff: 54.6;HBEC3-KT: 226.5;LHCN-M2: 60.9;TIME: 114.6;U-138 MG: 65.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA007879, CAB033770" Approved Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 7750000 3100000 "Cluster 41: Basophils - Cellular respiration" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "CAB033770: AB_2057427, HPA007879: AB_1078158" "unprognostic (1.26e-1)" "unprognostic (5.29e-3)" "prognostic unfavorable (7.53e-4)" "unprognostic (1.88e-2)" "unprognostic (7.68e-3)" "unprognostic (3.58e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (9.50e-4)" "unprognostic (3.18e-1)" "unprognostic (3.90e-3)" "unprognostic (9.69e-3)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.34e-5)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.00e-2)" 195.8 23.0 25.2 15.4 31.8 1.4 165.0 26.2 32.6 18.8 14.0 25.6 11.5 6.8 0.1 41.2 7.9 9.4 45.4 27.7 27.0 51.9 183.7 46.6 2.0 30.1 37.6 9.1 70.8 1.0 16.1 18.3 27.2 30.4 0.9 3.2 19.1 2.6 24.8 30.2 28.0 6.0 27.3 13.1 21.7 6.7 33.8 0.7 34.1 6.2 2.8 26.6 32.1 33.7 0.1 2.2 1.2 3.3 54.6 12.0 0.7 4.4 0.5 0.7 0.2 0.0 20.9 0.2 30.6 8.8 4.5 3.0 0.0 226.5 0.4 1.9 0.4 0.3 0.9 0.9 1.2 0.1 0.2 5.6 1.0 34.0 0.7 6.2 17.4 0.6 1.1 0.5 60.9 1.8 0.2 2.1 0.3 0.0 1.8 1.3 0.1 1.0 11.1 4.0 0.2 0.5 26.2 2.7 4.3 1.5 6.8 0.4 114.6 65.1 0.3 33.3 0.0 0.3 0.1 0.2 44.9 0.0 12.4 3.3 0.1 0.4 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.9 0.3 0.0 0.1 0.2 0.1 25.2 31.8 26.2 32.6 27.7 27.0 30.1 37.6 27.2 27.3 33.8 33.7 53.5 38.5 5.8 128.0 1.2 14.0 39.8 318.9 17.1 0.2 71.8 49.0 5.3 1.5 85.7 14.7 0.0 7.4 2.5 17.1 0.0 107.1 0.7 4.2 6.9 28.9 0.0 0.0 0.4 18.0 111.2 89.1 46.9 13.8 2.5 1.5 17.9 148.4 8.3 0.0 0.6 14.2 16.2 1.6 10.3 2.2 88.0 5.0 8.8 2.8 2.0 2.7 0.0 1.0 4.5 230.4 8.4 131.7 1.0 38.3 146.3 4.5 19.0 0.1 32.9 198.3 121.5 0.0 3.1 21.8 11.5 40.1 2.3 20.7 6.7 77.7 ANGPTL5 ENSG00000187151 "Angiopoietin like 5" Q86XS5 11 101890674-101916522 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "ovary: 22.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 19.4;Langerhans cells: 11.3;Leydig cells: 27.7;Melanocytes: 7.2;Peritubular cells: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "ASC diff: 2.7" "Region enhanced" "Detected in some" "spinal cord: 3.3" HPA038516 Uncertain "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA038516: AB_10672749" "unprognostic (8.28e-3)" "unprognostic (3.08e-2)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (3.23e-2)" "unprognostic (2.18e-1)" "unprognostic (4.88e-2)" "unprognostic (6.74e-4)" "unprognostic (1.96e-1)" "unprognostic (1.53e-8)" "unprognostic (3.40e-2)" "unprognostic (1.95e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-3)" 4.3 0.2 0.1 0.0 0.2 0.0 5.5 0.2 0.4 0.2 0.4 0.3 0.1 0.0 4.4 0.2 0.3 0.2 2.7 0.2 0.2 0.0 0.0 0.9 0.1 0.2 0.1 22.4 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.4 0.2 0.4 2.4 0.2 0.0 0.2 0.0 0.1 1.6 0.1 0.0 0.7 1.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 2.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.5 0.0 0.0 0.3 0.0 6.2 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.0 0.0 2.1 0.9 0.6 0.8 0.0 0.0 2.7 0.0 0.1 19.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.0 11.3 0.8 27.7 0.1 7.2 4.7 0.0 0.2 0.0 1.0 0.2 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.2 1.0 0.2 0.2 0.0 5.5 0.1 0.5 5.7 0.0 0.0 ANGPTL6 "AGF, ARP5" ENSG00000130812 "Angiopoietin like 6" Q8NI99 19 10092338-10102796 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 30.2" "Cell type enhanced" "Detected in some" "B-cells: 4.1;Hepatic stellate cells: 5.7;Hepatocytes: 8.2;Smooth muscle cells: 15.8;Spermatogonia: 6.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HMC-1: 58.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 450000 23000000 "Cluster 24: B-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.28e-1)" "unprognostic (2.18e-6)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (2.16e-1)" "unprognostic (1.02e-2)" "unprognostic (8.77e-2)" "unprognostic (5.25e-2)" "unprognostic (1.00e-1)" "unprognostic (2.99e-2)" "unprognostic (1.23e-2)" "unprognostic (1.85e-1)" "unprognostic (2.26e-10)" "unprognostic (8.96e-2)" "unprognostic (4.41e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" 0.3 0.3 0.8 2.1 0.7 2.8 0.3 0.8 1.1 0.2 0.4 0.6 0.7 0.1 0.2 0.3 0.7 0.4 0.2 0.7 0.8 0.5 30.2 0.5 3.3 1.7 1.1 0.3 1.1 0.1 0.4 2.2 1.3 0.2 0.4 0.1 0.2 0.0 0.0 0.3 3.5 0.2 1.2 3.4 1.6 1.6 1.0 0.8 0.3 0.0 3.3 0.5 0.2 1.7 0.3 0.0 0.0 0.1 0.1 0.0 0.4 0.2 0.1 0.0 0.2 0.0 0.1 7.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 2.0 0.2 0.2 0.0 0.5 58.9 0.0 0.2 0.1 0.1 0.3 0.0 0.6 0.4 0.3 0.0 0.0 1.3 4.7 0.2 0.4 1.1 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.3 0.0 0.5 0.0 0.0 5.0 0.0 0.1 0.1 0.0 0.0 5.1 1.4 2.9 0.2 0.7 0.7 0.0 0.3 0.0 0.6 0.4 0.4 0.7 0.4 0.4 0.1 0.9 0.2 0.4 0.0 0.4 0.2 0.1 0.5 0.2 0.8 0.7 0.8 1.1 0.7 0.8 1.7 1.1 1.3 1.2 1.0 1.7 0.3 0.0 0.0 0.0 4.1 0.3 0.1 0.4 0.0 0.1 0.4 0.3 0.4 2.8 0.3 0.0 0.0 0.2 1.7 0.1 1.9 0.3 0.3 0.0 0.3 0.2 0.0 0.4 0.9 0.0 0.2 2.5 0.5 0.1 0.0 0.1 5.7 8.2 2.3 0.0 0.6 0.0 0.0 0.0 0.3 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 2.1 0.0 0.2 0.5 0.2 0.2 0.0 0.1 15.8 0.5 6.3 0.0 0.0 0.3 1.0 0.9 0.1 0.1 ANGPTL7 "AngX, CDT6" ENSG00000171819 "Angiopoietin like 7" O43827 1 11189355-11195981 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Cardiomyocytes: 4.1;Enteroendocrine cells: 1.8;Fibroblasts: 6.9;Melanocytes: 3.6;Microglial cells: 1.9" "Cancer enriched" "Detected in some" 14 "melanoma: 18.4" "Region enhanced" "Detected in some" "thalamus: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 65 "SCLC-21H: 41.4" "Not detected" "Not detected" "Region enriched" "Detected in all" 13 "spinal cord: 62.2" "Secreted in other tissues" NA NA 1100000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.23e-2)" "unprognostic (6.95e-2)" "unprognostic (1.22e-1)" "unprognostic (2.67e-3)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.89e-2)" "unprognostic (2.02e-1)" "unprognostic (1.10e-1)" "unprognostic (3.97e-1)" "unprognostic (1.10e-1)" "unprognostic (1.58e-2)" "unprognostic (3.41e-3)" "unprognostic (1.92e-1)" "unprognostic (1.19e-3)" "unprognostic (2.49e-2)" 15.9 2.2 0.3 1.3 0.2 0.0 5.3 1.9 1.0 4.8 0.2 9.2 0.8 0.5 2.1 2.2 2.2 3.8 7.6 0.1 0.4 2.7 0.1 1.3 0.0 0.4 0.5 0.4 0.4 0.0 4.2 0.6 0.3 4.2 1.5 0.2 2.3 6.6 7.8 6.2 1.8 1.9 0.0 0.3 2.3 0.2 4.3 0.3 0.7 5.7 0.2 4.2 5.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 1.9 1.0 0.1 0.4 0.4 0.5 0.3 0.0 4.3 0.4 0.1 3.2 0.0 0.3 0.0 0.1 0.1 0.0 1.2 0.1 0.2 0.8 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.8 0.0 0.3 0.0 0.0 6.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.6 1.9 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 ANGPTL8 "C19orf80, RIFL, TD26" ENSG00000130173 "Angiopoietin like 8" Q6UXH0 19 11237450-11241943 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Hormone "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 409.8" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 151.2" "Cancer enriched" "Detected in some" 37 "liver cancer: 84.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "Hep G2: 37.0;MCF7: 21.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA042131 Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA 836000 350000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" Nucleoplasm "HPA042131: AB_10794413" "unprognostic (2.37e-2)" "unprognostic (1.86e-1)" "unprognostic (1.15e-1)" "unprognostic (1.31e-2)" "unprognostic (1.17e-1)" "unprognostic (1.00e-1)" "unprognostic (3.73e-1)" "unprognostic (2.80e-1)" "unprognostic (3.49e-1)" "unprognostic (1.02e-1)" "unprognostic (9.67e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.84e-6)" "unprognostic (1.09e-1)" "unprognostic (3.55e-1)" "unprognostic (4.57e-1)" "unprognostic (1.75e-2)" 35.7 0.8 1.1 0.2 1.0 0.1 22.5 0.1 1.7 1.2 0.0 1.4 0.4 0.9 1.6 0.3 0.8 0.4 1.8 0.9 0.6 4.0 409.8 0.4 0.1 0.7 0.6 1.1 0.9 0.0 0.3 0.1 0.5 0.8 0.0 0.1 1.3 0.1 0.8 0.9 1.2 0.1 0.3 0.4 0.7 0.5 1.1 0.0 1.0 0.0 0.0 1.1 1.0 0.9 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.2 1.3 37.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 21.2 0.0 0.7 0.2 0.0 0.0 0.1 0.4 1.0 0.0 0.3 0.0 0.3 0.4 0.9 0.0 0.4 0.6 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.2 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.1 1.7 0.9 0.6 0.7 0.6 0.5 0.3 1.1 0.9 0.6 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.4 0.2 0.8 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.3 0.2 0.0 2.7 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 4.6 151.2 0.1 0.0 0.0 0.0 0.0 4.4 0.0 1.9 0.9 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 3.3 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.3 0.1 0.2 0.0 0.1 ANK1 "ANK, SPH1" ENSG00000029534 "Ankyrin 1" P16157 8 41653220-41896762 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 993.4;tongue: 629.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 164.7;Cone photoreceptor cells: 87.6;Erythroid cells: 250.2;Inhibitory neurons: 176.8;Skeletal myocytes: 51.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 9.2;naive B-cell: 7.8;plasmacytoid DC: 3.4" "Group enriched" "Detected in many" 4 "B-cells: 9.2;dendritic cells: 3.4" "Group enriched" "Detected in many" 4 "HEL: 125.2;K-562: 134.3;RH-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004842, HPA056953" Supported Supported "Intracellular and membrane" NA NA 4200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA004842: AB_1844827, HPA056953: AB_2683284" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (4.22e-3)" "unprognostic (2.31e-3)" "unprognostic (1.76e-7)" "unprognostic (2.03e-1)" "unprognostic (2.15e-1)" "unprognostic (2.52e-1)" "unprognostic (2.95e-1)" "unprognostic (3.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-1)" "unprognostic (1.40e-1)" "unprognostic (3.86e-1)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.04e-1)" 1.8 1.1 0.4 1.6 2.0 95.2 1.0 34.1 17.3 0.3 0.0 0.5 1.5 0.1 0.1 8.7 0.4 0.8 98.0 0.3 12.5 0.6 0.3 0.7 4.4 26.8 32.6 0.3 0.8 62.1 1.1 2.1 27.1 4.2 0.2 6.3 8.1 0.7 993.4 0.6 0.9 0.3 10.6 2.2 4.4 0.6 8.4 0.7 0.6 629.0 4.0 1.8 0.5 5.4 0.0 16.8 0.5 0.0 0.2 2.9 0.0 4.9 32.8 1.5 0.7 0.1 0.0 7.7 1.5 3.5 0.6 2.8 0.8 0.5 0.7 3.2 0.1 125.2 0.7 0.0 0.1 0.3 0.4 4.2 0.6 0.4 0.0 0.7 0.1 0.0 134.3 2.8 2.1 0.3 0.0 1.6 1.7 0.1 0.1 0.9 160.2 0.8 0.7 0.5 2.2 1.4 0.1 2.3 0.0 5.9 2.0 3.2 0.8 0.5 0.9 27.6 0.2 0.0 0.2 4.7 2.9 0.0 0.0 1.5 0.2 0.0 0.1 0.0 0.4 9.2 0.3 0.4 0.1 7.8 0.0 0.0 0.4 0.1 0.0 3.4 1.0 0.7 0.4 2.0 34.1 17.3 0.3 12.5 26.8 32.6 27.1 10.6 8.4 5.4 5.5 0.0 0.0 1.3 8.3 0.6 1.4 2.2 0.6 15.4 0.3 0.1 164.7 0.0 1.0 0.0 87.6 1.1 0.2 0.1 1.9 0.1 7.0 0.1 0.1 4.6 1.2 250.2 12.9 0.0 0.5 2.9 5.6 0.5 0.0 2.2 0.4 0.1 19.7 3.3 176.8 0.7 2.0 0.8 3.7 6.3 0.3 2.6 0.0 3.7 0.4 1.0 0.0 7.1 2.0 1.1 1.2 0.4 5.7 1.3 0.1 0.3 0.6 5.5 0.0 51.6 5.7 0.2 1.0 0.1 0.0 0.4 1.7 0.1 0.0 1.8 ANKLE1 "ANKRD41, FLJ39369, LEMD6" ENSG00000160117 "Ankyrin repeat and LEM domain containing 1" Q8NAG6 19 17281645-17287646 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 25.6;brain: 8.8" "Cell type enriched" "Detected in some" 10 "Erythroid cells: 70.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 77.2;HL-60: 34.6;NB-4: 41.7;U-937: 57.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA026789, HPA073498" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Cytosol" "HPA026789: AB_10611675, HPA073498: AB_2686612" "unprognostic (5.66e-2)" "unprognostic (2.21e-1)" "unprognostic (6.90e-2)" "prognostic unfavorable (4.86e-5)" "unprognostic (2.73e-1)" "unprognostic (1.72e-3)" "unprognostic (2.19e-2)" "unprognostic (2.09e-2)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "unprognostic (7.89e-4)" "unprognostic (5.86e-2)" "unprognostic (0.00e+0)" "unprognostic (2.03e-1)" "unprognostic (1.61e-1)" "unprognostic (2.00e-3)" "unprognostic (4.30e-2)" 0.7 0.9 4.5 2.3 2.7 25.6 0.6 8.8 5.5 0.7 0.6 0.5 0.9 1.0 1.2 0.7 0.6 0.7 1.0 3.2 2.3 0.4 0.6 0.8 4.1 1.6 1.4 1.5 1.7 0.4 0.5 1.2 1.7 0.7 0.5 3.6 1.5 0.6 0.3 2.4 0.8 0.8 0.4 2.2 0.8 1.5 3.3 1.3 0.9 0.5 3.1 0.7 0.4 2.7 0.9 0.8 3.7 1.7 0.4 0.6 3.2 1.1 0.3 0.6 0.6 17.1 1.5 77.2 0.7 0.5 0.6 1.5 28.4 0.4 0.6 22.3 3.4 29.1 13.1 0.6 0.3 34.6 12.5 0.3 1.0 2.7 0.2 0.9 0.6 6.4 4.2 9.2 0.4 0.9 24.2 41.7 10.2 0.3 2.6 17.3 1.0 8.7 0.4 1.7 1.2 7.1 6.8 0.9 0.7 1.5 0.6 20.1 1.4 1.0 1.2 1.4 1.0 1.3 0.9 27.8 0.7 57.2 1.3 0.9 0.9 0.6 0.5 1.9 0.3 1.6 0.4 0.5 1.1 0.9 0.5 0.4 1.5 0.3 1.4 0.9 0.4 0.6 4.5 2.7 8.8 5.5 3.2 2.3 1.6 1.4 1.7 0.4 3.3 2.7 0.4 0.0 0.5 0.7 1.1 0.8 0.8 0.3 0.0 1.9 0.5 0.6 0.8 0.0 0.1 0.0 0.0 1.6 0.4 0.4 0.0 0.2 0.3 0.2 0.4 0.4 0.0 70.7 1.4 0.2 0.7 0.6 0.0 0.8 1.3 1.1 0.0 0.1 0.8 0.0 1.6 0.5 0.0 0.9 1.3 0.0 1.8 1.1 0.0 1.0 3.0 0.5 1.0 1.0 1.6 0.3 0.1 1.5 0.9 0.5 0.0 0.1 0.9 1.5 6.6 0.6 0.4 0.5 1.0 0.0 0.4 0.4 0.5 0.3 0.3 0.2 ANKRD54 LIAR ENSG00000100124 "Ankyrin repeat domain 54" Q6NXT1 22 37830855-37849327 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071287 Approved Approved Nucleoplasm,Microtubules,Midbody Yes No "Cluster 15: NK-cells - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Microtubules, Midbody" Nucleoplasm "HPA071287: AB_2686380" "unprognostic (5.36e-2)" "prognostic favorable (2.06e-4)" "unprognostic (1.02e-1)" "prognostic favorable (7.38e-5)" "unprognostic (1.14e-1)" "unprognostic (1.50e-1)" "unprognostic (1.65e-2)" "unprognostic (1.77e-2)" "unprognostic (1.06e-1)" "unprognostic (3.41e-2)" "prognostic favorable (6.16e-4)" "unprognostic (2.53e-1)" "unprognostic (6.33e-2)" "unprognostic (1.13e-1)" "unprognostic (5.07e-2)" "unprognostic (1.89e-1)" "unprognostic (3.02e-3)" 8.6 18.7 22.4 5.9 20.8 6.9 9.1 22.6 23.3 13.0 28.7 16.4 7.1 12.9 7.8 14.0 23.8 6.3 12.4 23.0 26.2 14.9 15.6 8.4 6.4 22.6 24.7 17.8 18.1 11.7 19.2 5.4 21.6 13.7 6.6 6.3 13.9 11.0 12.6 11.3 8.9 9.5 22.0 9.2 10.9 30.9 26.1 10.4 13.8 8.7 7.2 14.0 10.9 20.3 18.5 18.6 15.4 23.0 19.9 11.3 8.1 24.8 19.2 41.1 25.2 11.8 7.3 17.8 10.1 16.5 13.3 16.4 19.5 14.1 19.9 14.2 39.5 9.3 17.3 28.3 17.7 17.8 20.8 10.1 14.2 22.6 13.3 10.3 25.5 13.1 11.9 12.7 19.1 19.8 17.6 21.1 4.4 24.5 16.5 20.2 18.3 11.3 23.2 6.4 26.4 14.1 20.7 18.8 30.8 7.0 19.3 28.0 15.1 24.5 25.6 12.9 18.6 13.3 11.7 14.3 20.1 15.1 17.9 3.5 4.5 2.2 5.4 5.5 5.4 3.9 5.1 4.0 5.7 5.2 5.3 2.6 2.7 10.2 9.3 5.3 2.4 3.3 22.4 20.8 22.6 23.3 23.0 26.2 22.6 24.7 21.6 22.0 26.1 20.3 8.4 12.8 14.5 11.8 14.4 15.8 11.0 12.4 12.0 18.3 16.9 15.6 8.1 24.3 12.2 18.4 29.2 20.9 14.0 19.9 39.2 17.1 6.4 47.8 12.6 10.9 9.0 12.8 9.4 14.7 17.7 12.3 12.2 8.5 9.5 23.3 13.6 12.0 13.2 26.9 9.4 14.3 12.2 12.5 10.7 7.7 18.0 8.8 10.6 2.8 9.2 18.5 17.5 13.6 8.6 11.3 15.3 21.4 8.4 11.4 19.2 22.0 48.2 23.2 6.6 13.1 13.4 65.6 42.1 12.7 17.6 16.8 13.3 25.4 20.7 9.9 ANKRD60 "bA196N14.3, C20orf86" ENSG00000124227 "Ankyrin repeat domain 60" Q9BZ19 20 58218495-58228653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 3.6" "Group enriched" "Detected in some" 25 "Early spermatids: 3.7;Late spermatids: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060561 Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA060561: AB_2684318" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.9 0.1 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ANKS6 "ANKRD14, FLJ36928, NPHP16, SAMD6" ENSG00000165138 "Ankyrin repeat and sterile alpha motif domain containing 6" Q68DC2 9 98731329-98796965 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.8;Inhibitory neurons: 48.6;Oligodendrocytes: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA008355 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoli "Nucleoplasm, Cytosol" "HPA008355: AB_2058277" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (9.31e-2)" "unprognostic (9.15e-3)" "unprognostic (6.90e-3)" "unprognostic (1.22e-1)" "unprognostic (4.29e-3)" "unprognostic (4.10e-2)" "unprognostic (1.48e-1)" "unprognostic (3.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.94e-2)" "prognostic favorable (3.44e-5)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (3.95e-2)" "unprognostic (2.68e-1)" 5.7 4.8 8.0 3.2 8.8 1.5 4.7 14.3 10.0 9.5 7.6 10.5 4.2 8.9 4.9 8.7 10.2 3.3 3.9 8.1 7.7 9.4 2.7 6.6 2.4 12.5 8.9 10.3 12.8 5.5 4.8 2.0 12.4 5.5 4.9 2.2 5.4 2.3 3.7 5.3 7.7 4.9 8.2 3.2 11.5 5.7 10.1 2.6 13.6 1.0 2.9 8.7 5.2 9.7 8.2 12.3 10.9 19.3 9.0 7.3 7.4 5.9 10.0 6.5 7.7 6.7 5.8 15.2 4.4 8.4 9.2 23.9 8.1 9.9 3.4 21.2 8.3 3.6 7.7 2.9 8.8 2.0 2.3 8.9 12.0 8.7 8.9 7.9 7.4 13.8 26.0 3.5 5.0 13.5 0.9 3.9 17.3 36.3 12.2 10.2 26.8 1.2 11.7 5.1 7.1 8.1 2.5 14.2 6.7 8.8 0.0 4.1 7.6 6.5 7.2 18.4 5.8 6.8 12.1 2.4 9.4 6.8 9.8 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.4 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 8.0 8.8 14.3 10.0 8.1 7.7 12.5 8.9 12.4 8.2 10.1 9.7 3.5 6.4 10.5 16.0 2.4 1.8 0.9 8.2 5.2 12.0 1.5 2.2 4.4 10.0 7.7 12.9 8.4 3.1 1.5 5.1 3.9 4.2 3.0 3.7 5.3 3.2 4.9 0.8 52.8 8.9 2.7 4.9 7.7 3.9 1.3 6.2 1.8 1.7 1.9 0.0 48.6 7.1 0.0 1.3 0.9 5.8 2.8 0.9 0.0 9.4 0.7 1.9 2.1 14.1 54.2 9.3 3.1 4.5 1.4 3.9 4.8 5.9 11.1 0.8 0.0 2.7 3.2 3.8 5.9 5.6 1.1 1.1 2.4 6.2 10.4 2.9 ANOS1 "ADMLX, KAL, KAL1, KALIG-1, WFDC19" ENSG00000011201 "Anosmin 1" P23352 X 8528874-8732137 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.1" "Cell type enriched" "Detected in many" 11 "Alveolar cells type 1: 240.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 40.4;NTERA-2: 37.0;U-2 OS: 17.6" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (2.93e-1)" "unprognostic (5.33e-2)" "unprognostic (9.54e-2)" "unprognostic (4.16e-3)" "unprognostic (7.77e-3)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" "unprognostic (1.17e-3)" "unprognostic (4.53e-2)" "unprognostic (6.43e-2)" "unprognostic (2.09e-2)" "unprognostic (6.24e-2)" "unprognostic (1.71e-2)" "unprognostic (9.38e-3)" "unprognostic (6.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.56e-2)" 6.6 4.0 7.6 1.1 10.5 0.3 3.7 6.0 7.3 4.4 0.9 0.6 0.3 0.5 3.1 1.3 1.1 1.7 5.0 8.3 12.2 0.8 0.8 43.1 1.9 13.8 11.5 0.3 0.4 15.1 0.5 1.2 14.8 4.1 1.0 19.6 2.4 4.4 10.5 3.1 0.6 0.7 18.6 0.8 0.8 3.9 12.6 4.0 9.3 6.8 0.9 1.2 1.2 17.9 0.1 0.0 1.9 0.0 0.0 0.0 2.2 0.8 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.7 4.0 0.2 5.5 0.5 5.6 0.0 0.0 0.0 1.5 0.1 3.1 0.3 0.1 40.4 0.0 0.1 0.0 0.0 0.5 0.4 0.3 0.0 37.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 2.1 0.1 1.9 0.5 0.0 4.8 0.0 1.0 0.0 0.0 17.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 10.5 6.0 7.3 8.3 12.2 13.8 11.5 14.8 18.6 12.6 17.9 1.7 240.4 12.6 0.0 0.0 0.0 4.7 0.0 13.1 20.5 6.2 3.4 6.2 0.0 19.8 0.0 4.2 0.1 0.0 0.0 0.0 0.9 0.2 0.4 1.5 1.6 0.0 0.0 0.0 0.0 0.3 10.9 0.0 0.1 1.3 2.2 6.1 0.0 5.1 0.0 0.0 0.0 0.0 2.9 0.0 0.3 0.6 3.0 0.0 0.0 0.2 17.8 0.0 0.0 0.0 1.5 0.1 1.2 0.0 3.1 0.0 0.2 3.6 1.6 0.0 8.7 3.3 0.6 1.6 1.5 0.0 0.1 0.3 0.8 0.4 1.1 ANTXR1 "ATR, FLJ10601, FLJ21776, TEM8" ENSG00000169604 "ANTXR cell adhesion molecule 1" Q9H6X2 2 69013176-69249327 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor Hypotrichosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 130.6;Endometrial stromal cells: 78.1;Oligodendrocyte precursor cells: 141.8;Skeletal myocytes: 111.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 367.9;TIME: 240.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054785 Uncertain Vesicles "Intracellular and membrane" NA NA 11000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA054785: " "unprognostic (1.44e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (8.49e-2)" "unprognostic (4.77e-2)" "unprognostic (3.61e-1)" "unprognostic (4.34e-2)" "unprognostic (1.05e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (4.15e-3)" "unprognostic (9.05e-3)" "unprognostic (1.15e-1)" "unprognostic (3.48e-3)" "unprognostic (2.26e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (1.22e-5)" "unprognostic (2.09e-2)" 38.7 63.1 25.7 20.3 24.1 0.2 32.7 26.6 16.1 77.8 70.2 32.7 12.9 81.4 25.2 33.9 44.1 114.6 39.9 27.9 69.2 11.0 8.2 44.8 12.1 42.5 49.5 107.2 6.7 35.4 14.6 78.8 45.6 47.9 21.4 9.5 28.6 55.4 11.3 39.3 20.2 62.1 36.5 28.3 14.5 11.7 38.3 10.5 43.3 24.0 13.0 52.3 42.4 36.6 36.8 39.5 36.4 33.9 162.7 78.8 0.6 57.1 115.6 63.2 51.5 0.4 3.0 0.0 31.6 147.4 41.7 31.7 30.7 33.8 59.9 0.1 24.4 9.5 90.5 11.9 71.1 7.6 5.1 129.7 13.4 55.5 36.4 140.9 17.3 19.4 6.7 0.1 367.9 15.2 22.1 0.5 35.8 0.0 26.5 0.1 186.3 0.6 13.8 27.9 21.1 91.0 104.3 0.5 37.5 23.7 11.0 2.3 240.4 71.3 61.6 72.1 59.6 0.2 0.1 0.2 37.3 6.7 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.7 24.1 26.6 16.1 27.9 69.2 42.5 49.5 45.6 36.5 38.3 36.6 4.7 6.4 20.0 130.6 0.0 49.5 21.1 15.4 17.6 1.7 7.9 13.8 6.8 0.0 8.3 0.0 0.0 0.7 0.1 0.0 0.0 1.5 37.9 5.5 78.1 4.3 0.0 0.0 61.9 2.6 1.9 68.2 0.0 11.7 1.3 22.1 3.3 0.1 4.0 0.0 64.3 0.0 4.1 0.8 19.8 33.9 42.6 2.9 24.9 40.3 0.6 13.6 0.0 141.8 1.3 1.1 0.0 67.7 1.2 10.1 0.0 0.1 9.9 0.8 19.7 111.7 59.6 5.2 2.7 4.6 23.4 1.4 1.7 26.4 0.0 8.9 ANTXR2 "CMG-2, CMG2, FLJ31074" ENSG00000163297 "ANTXR cell adhesion molecule 2" P58335 4 79901146-80125454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 215.4;HHSteC: 197.9;LHCN-M2: 221.0;U-2197: 176.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 13000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.01e-1)" "unprognostic (1.79e-2)" "unprognostic (1.95e-2)" "unprognostic (4.87e-2)" "unprognostic (5.63e-2)" "unprognostic (2.30e-2)" "unprognostic (6.75e-2)" "unprognostic (3.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (1.27e-1)" "prognostic unfavorable (3.34e-6)" "unprognostic (1.03e-3)" "unprognostic (2.98e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-1)" 60.9 30.0 4.1 35.4 4.1 18.7 18.7 3.6 6.4 52.2 5.0 39.9 23.0 95.4 21.9 24.5 31.2 54.9 31.8 3.6 5.0 17.1 34.4 24.7 16.2 4.7 5.0 75.0 4.6 27.8 1.6 90.0 4.2 110.2 42.7 1.6 10.1 90.3 6.1 6.1 29.6 108.3 5.5 18.3 23.2 8.4 4.0 10.7 4.9 21.7 16.1 53.1 12.0 4.4 15.5 1.9 34.6 6.6 215.4 118.0 3.1 48.3 124.6 17.5 19.9 0.6 11.8 0.0 0.8 76.8 11.4 4.5 4.4 49.7 66.9 2.2 4.2 12.2 1.3 4.8 197.9 51.6 29.5 145.3 15.2 132.7 68.3 150.2 52.6 1.6 27.1 35.8 221.0 0.0 1.1 57.1 5.7 21.7 70.3 2.4 19.8 9.0 12.0 14.4 30.6 41.2 4.9 0.6 8.2 16.3 0.7 11.0 69.8 155.7 9.7 176.7 103.4 3.1 0.0 0.1 78.6 39.4 49.0 72.7 17.5 61.6 12.8 9.5 13.8 23.5 21.4 13.1 32.2 9.4 11.3 5.9 54.4 4.3 18.0 32.2 40.4 14.0 4.1 4.1 3.6 6.4 3.6 5.0 4.7 5.0 4.2 5.5 4.0 4.4 6.4 12.8 10.0 23.5 25.7 7.0 15.5 6.5 4.0 6.9 4.0 2.2 24.9 4.3 10.2 0.0 29.2 18.3 24.9 42.4 3.9 4.2 2.3 7.7 69.3 15.5 18.6 6.3 25.4 6.7 29.0 58.7 4.1 6.1 60.1 8.9 15.0 24.9 17.7 0.0 2.1 15.1 4.1 13.4 28.9 5.3 39.1 28.3 1.8 45.9 53.7 6.9 4.1 19.1 0.8 45.5 28.9 63.9 14.1 13.9 16.9 2.5 4.9 21.4 39.5 32.5 28.5 0.6 2.1 0.9 4.3 6.6 24.4 18.3 13.3 1.6 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512941-36724549 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.3;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 77.9;Kupffer cells: 119.7;Macrophages: 77.1;Microglial cells: 233.3;monocytes: 67.5;NK-cells: 90.6;T-cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 298.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "GAMG: 4.8;NB-4: 26.5;THP-1: 20.2;U-937: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA021666, HPA026716" Approved Uncertain Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 7.5 5.1 2.4 33.7 2.2 43.3 3.8 2.1 3.1 5.7 4.7 10.4 9.5 2.8 1.5 3.3 3.5 15.6 2.0 2.1 3.6 1.9 13.2 12.7 35.1 6.6 5.1 2.6 1.5 1.5 0.9 11.2 5.7 2.5 13.3 0.8 3.7 2.8 0.5 0.8 12.1 9.3 4.0 64.9 7.0 1.3 5.1 13.9 1.8 0.9 15.1 13.9 1.3 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 26.5 0.1 0.0 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 8.9 0.0 1.8 298.5 97.8 43.6 251.9 9.0 2.6 2.2 30.7 183.1 0.3 4.8 37.3 97.9 106.8 113.2 2.7 0.7 207.3 2.4 2.2 2.1 3.1 2.1 3.6 6.6 5.1 5.7 4.0 5.1 8.6 1.3 0.0 9.6 1.3 3.6 0.8 0.1 0.0 0.0 1.1 0.6 1.7 0.5 1.5 2.5 0.0 0.0 0.2 77.9 9.2 1.9 0.3 0.6 0.4 0.3 1.4 15.5 16.0 12.4 0.0 0.2 3.1 2.6 0.4 5.1 0.7 2.5 0.9 32.8 0.0 8.1 0.3 0.0 119.7 20.3 1.2 0.0 77.1 0.0 233.3 67.5 2.8 90.6 12.1 38.6 0.0 3.8 0.4 13.6 0.1 0.3 0.5 0.7 0.3 0.0 0.3 0.5 0.0 0.1 0.4 0.3 0.1 54.1 0.6 0.9 0.2 AOC1 "ABP, ABP1, DAO" ENSG00000002726 "Amine oxidase copper containing 1" P19801 7 150824627-150861504 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 227.2;kidney: 136.5;placenta: 496.7" "Cell type enhanced" "Detected in many" "Collecting duct cells: 272.2;Distal enterocytes: 517.5;Paneth cells: 532.1;Proximal enterocytes: 957.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 61.3;endometrial cancer: 39.1;pancreatic cancer: 26.9;renal cancer: 69.4;stomach cancer: 43.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 12 "eosinophil: 31.2" "Lineage enriched" "Detected in many" 22 "granulocytes: 31.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 20.5;HaCaT: 6.2;NB-4: 6.4;RPMI-8226: 7.7;THP-1: 27.1" "Low region specificity" "Detected in many" "HPA031032, HPA031033" Approved "Secreted in other tissues" NA NA 2500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 43: THP-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "HPA031032: AB_10670150, HPA031033: AB_10669670" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.84e-2)" "unprognostic (6.31e-3)" "unprognostic (8.31e-3)" "unprognostic (9.07e-3)" "unprognostic (6.42e-2)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (3.11e-1)" "prognostic favorable (1.71e-4)" "unprognostic (5.32e-3)" "unprognostic (3.62e-2)" "unprognostic (1.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.64e-1)" 0.7 0.1 0.3 13.0 0.2 1.9 0.2 0.3 0.3 7.2 0.4 142.2 184.0 2.1 1.9 3.3 0.1 1.8 0.7 0.3 0.2 136.5 5.8 0.6 1.3 0.5 0.5 0.3 1.4 0.0 0.0 496.7 0.5 6.1 94.1 0.1 0.6 1.0 0.1 1.4 227.2 3.4 0.3 0.5 18.0 2.1 0.6 2.1 0.2 0.0 3.8 0.8 0.4 0.5 0.0 0.1 0.1 0.4 0.0 0.0 1.0 0.2 0.0 0.0 0.0 3.2 20.5 0.0 2.7 0.0 1.7 6.2 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.3 0.1 6.4 0.2 1.9 0.0 0.0 0.0 7.7 0.3 0.2 2.2 2.5 0.1 0.9 0.0 0.3 0.8 27.1 0.6 0.2 0.1 0.6 0.0 0.2 0.1 0.1 0.2 1.0 0.1 0.2 0.1 31.2 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.3 0.3 0.3 0.2 0.5 0.5 0.5 0.3 0.6 0.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.8 272.2 0.0 2.1 0.0 517.5 15.6 0.0 7.1 1.9 0.5 0.4 43.3 0.0 0.1 3.3 63.4 0.5 13.7 4.8 5.7 0.0 0.0 0.0 2.8 0.0 0.1 129.7 2.0 0.0 1.7 18.4 0.0 1.0 0.0 0.0 66.2 0.0 0.0 0.0 0.0 3.7 532.1 0.0 0.0 0.7 957.9 145.2 0.2 0.0 0.0 0.0 0.3 3.7 1.3 0.0 0.1 3.4 0.9 0.0 117.9 0.3 AOC2 "DAO2, RAO" ENSG00000131480 "Amine oxidase copper containing 2" O75106 17 42844580-42850707 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Early spermatids: 29.5" "Cancer enhanced" "Detected in some" "testis cancer: 3.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "ASC diff: 11.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA057779 Uncertain "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "HPA057779: " "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (5.10e-4)" "unprognostic (1.90e-2)" "unprognostic (1.48e-2)" "unprognostic (2.42e-1)" "unprognostic (4.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.39e-1)" "unprognostic (3.64e-2)" "unprognostic (2.16e-2)" "unprognostic (8.27e-3)" "unprognostic (4.55e-5)" "unprognostic (3.55e-2)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.47e-4)" 5.8 1.1 1.9 0.6 2.1 0.9 2.6 1.9 3.2 1.3 0.6 1.3 0.3 1.0 0.5 0.7 1.6 0.7 0.7 2.4 1.9 1.2 3.4 2.3 0.5 2.0 1.6 1.1 0.7 0.2 2.0 0.4 2.0 1.5 0.2 1.5 0.6 0.5 1.6 1.3 0.8 0.6 1.1 1.6 0.8 4.8 2.0 0.3 0.9 0.6 0.6 1.8 1.2 1.9 0.2 2.3 0.5 2.5 11.2 1.1 6.0 0.8 0.7 1.6 2.2 1.8 0.2 0.9 1.1 0.2 0.7 1.0 2.2 0.6 3.2 2.0 6.0 0.3 1.3 1.9 0.7 0.3 2.2 1.7 2.0 1.5 2.3 0.4 0.4 3.1 0.6 2.1 0.4 0.3 0.5 0.9 0.8 0.2 0.7 1.1 2.3 1.9 0.3 3.6 0.8 0.5 0.1 0.8 3.4 4.6 0.4 0.2 0.4 1.5 3.2 2.0 1.0 4.6 4.9 0.9 0.4 2.2 0.8 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.9 2.1 1.9 3.2 2.4 1.9 2.0 1.6 2.0 1.1 2.0 1.9 1.1 0.0 0.5 1.6 0.3 1.0 0.5 0.1 0.0 0.5 0.9 0.9 0.4 0.0 0.7 0.0 2.1 0.1 0.4 0.0 0.0 0.3 29.5 1.4 0.7 1.4 0.0 0.0 1.8 0.4 0.1 0.2 0.0 2.8 0.0 0.5 0.4 0.7 0.1 0.0 1.2 0.2 0.0 0.3 0.6 5.0 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.2 0.1 0.0 0.0 1.2 0.1 0.2 0.4 0.8 0.0 0.5 1.0 2.3 2.1 0.4 1.6 0.0 0.2 0.4 0.2 0.6 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 422.8" "Group enriched" "Detected in many" 4 "Adipocytes: 58.2;Peritubular cells: 74.9;Sertoli cells: 118.3;Smooth muscle cells: 93.0;Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "ASC diff: 307.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" NA NA 240000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" 422.8 48.4 2.6 31.9 3.2 1.4 169.2 2.5 4.2 52.8 2.7 210.8 17.3 95.1 33.5 88.0 84.8 50.7 50.2 2.9 2.5 24.1 19.1 218.6 12.4 2.5 2.5 26.5 12.0 8.4 5.4 28.0 2.6 59.1 41.0 1.7 14.7 103.6 17.8 24.6 57.6 144.8 2.3 21.4 66.6 12.8 2.4 5.9 28.2 22.9 3.9 142.1 50.9 2.5 0.1 1.5 0.2 1.0 307.5 0.3 5.0 0.3 0.1 0.2 0.8 0.9 0.0 0.7 0.7 0.1 0.2 0.5 0.8 0.2 0.8 1.5 5.7 0.4 0.5 18.4 0.8 0.3 1.0 3.3 1.0 0.3 0.8 0.0 0.2 2.2 0.3 1.7 0.6 0.2 0.2 1.4 0.7 0.1 0.4 0.7 0.8 3.0 0.1 2.2 0.3 0.4 0.0 0.2 2.0 2.2 0.1 0.1 0.0 0.3 2.7 1.2 0.4 4.8 5.9 0.6 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 3.2 2.5 4.2 2.9 2.5 2.5 2.5 2.6 2.3 2.4 2.5 58.2 3.2 6.0 0.0 0.5 2.9 0.1 0.0 2.2 0.0 1.1 2.2 9.5 0.0 1.9 0.0 0.0 0.1 0.4 0.1 0.0 0.2 4.5 0.8 2.3 12.3 0.0 0.0 0.4 0.2 0.1 11.3 0.0 1.4 1.3 2.1 20.7 0.2 1.4 0.0 0.3 0.1 0.0 1.4 2.7 2.6 3.4 0.9 3.6 3.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 74.9 0.0 0.4 0.1 1.4 1.0 0.4 118.3 2.6 93.0 1.1 1.3 0.7 1.8 0.3 0.6 74.6 0.1 0.3 AP000721.1 ENSG00000256100 "Novel transcript" 11 63974620-63988346 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 6.4;Alveolar cells type 2: 7.2;Club cells: 3.7;Respiratory ciliated cells: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055942 Uncertain NA NA "Cluster 11: Alveolar cells - Smell perception" "HPA055942: AB_2682979" "unprognostic (3.25e-1)" "unprognostic (1.20e-1)" "unprognostic (5.96e-2)" "unprognostic (3.95e-1)" "unprognostic (2.67e-1)" "unprognostic (7.06e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 6.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 AP006621.6 ENSG00000288675 "Proapoptotic nucleolar protein 1" I0J062 11 797511-799190 "Predicted intracellular proteins" Apoptosis "Tumor suppressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.3;pancreas: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 5.5;SCLC-21H: 4.2" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 28: BEWO - Transcription regulation" 0.3 0.6 0.9 0.4 1.0 1.0 0.0 3.3 1.6 0.1 0.5 0.2 0.3 0.3 0.6 0.3 0.2 0.3 0.2 1.1 0.9 0.2 0.2 0.2 0.6 0.6 0.5 0.3 2.4 0.1 0.2 0.7 0.3 0.0 1.2 0.7 0.1 0.1 1.1 0.2 0.1 0.4 0.7 0.4 0.6 0.8 0.1 0.2 0.0 0.1 0.1 0.9 1.0 0.8 1.4 2.5 0.3 0.6 5.5 1.7 0.2 0.3 0.1 0.6 1.1 1.3 0.6 0.6 0.6 2.5 0.3 0.1 0.1 2.5 2.1 0.9 0.8 0.6 0.3 0.8 2.6 0.9 0.3 0.2 0.2 0.5 0.1 1.3 0.5 1.3 0.4 1.2 1.3 1.6 1.8 1.1 0.5 1.6 0.4 0.1 0.7 0.3 4.2 1.9 0.6 1.1 0.7 0.3 0.8 0.4 0.7 1.0 0.7 0.5 0.8 1.3 0.8 1.0 1.0 1.0 1.0 0.8 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.3 0.9 0.5 0.1 0.1 0.0 0.0 0.9 1.0 3.3 1.6 1.1 0.9 0.6 0.5 0.7 0.4 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AP4E1 "AP-4-EPSILON, SPG51" ENSG00000081014 "Adaptor related protein complex 4 subunit epsilon 1" Q9UPM8 15 50908672-51005895 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041749, HPA041891" Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 59: Non-specific - Transcription" "HPA041749: AB_10794490, HPA041891: AB_10796462" "unprognostic (1.72e-2)" "unprognostic (3.44e-1)" "unprognostic (9.21e-2)" "unprognostic (2.22e-3)" "unprognostic (1.27e-1)" "unprognostic (9.46e-2)" "unprognostic (6.83e-3)" "unprognostic (1.06e-2)" "unprognostic (2.37e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-1)" "unprognostic (6.84e-2)" "unprognostic (3.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" "unprognostic (2.03e-2)" 3.7 3.0 2.5 4.4 2.9 3.1 3.0 3.3 2.7 3.7 3.2 3.6 3.0 4.3 2.1 4.7 3.2 2.6 3.9 2.4 2.6 2.8 2.9 3.1 5.5 2.9 2.8 2.9 2.2 5.1 2.4 4.7 2.9 2.7 3.4 3.8 3.3 2.6 8.2 5.4 3.2 4.5 2.6 4.6 2.9 3.9 3.0 6.5 3.8 6.3 4.7 4.0 4.1 3.5 11.5 8.7 6.0 7.1 7.9 12.0 11.7 11.1 8.9 10.7 11.1 10.7 1.8 11.2 4.3 12.5 10.8 13.7 9.0 9.6 12.4 12.3 4.6 9.8 14.5 4.3 11.1 12.1 8.2 12.2 11.6 13.4 21.0 6.6 7.2 8.8 9.1 6.3 14.7 15.4 7.1 6.9 3.9 5.2 4.4 9.7 8.5 6.9 7.9 10.4 4.1 6.7 11.8 8.4 8.7 10.7 7.6 11.7 10.0 15.7 5.8 9.5 15.9 9.6 11.7 14.1 12.3 26.1 7.3 2.7 0.6 0.3 0.8 0.9 0.5 0.5 0.6 0.7 0.6 0.3 0.4 0.9 0.1 0.5 0.5 0.4 0.3 0.4 2.5 2.9 3.3 2.7 2.4 2.6 2.9 2.8 2.9 2.6 3.0 3.5 6.6 6.4 6.1 17.6 8.7 5.7 1.5 3.8 4.0 9.8 4.9 3.7 10.4 2.8 8.4 5.5 18.8 7.3 7.7 7.9 0.0 4.9 2.0 5.9 10.0 7.8 3.0 6.9 26.7 4.8 5.7 4.7 7.1 6.2 10.2 7.2 6.8 8.1 7.2 8.4 27.0 5.3 2.0 17.0 4.1 1.4 5.9 10.2 1.8 25.3 6.5 3.9 8.2 19.1 36.0 10.6 2.4 4.1 9.6 2.2 6.2 3.6 4.8 11.2 6.6 7.1 6.6 10.2 7.7 6.6 7.0 7.3 9.6 4.8 5.5 2.4 APBB1 "Fe65, RIR" ENSG00000166313 "Amyloid beta precursor protein binding family B member 1" O00213 11 6395124-6419414 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 85.6" "Lineage enriched" "Detected in all" 5 "T-cells: 85.6" "Cell line enhanced" "Detected in many" "SCLC-21H: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038521, HPA038522" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA038521: AB_2676058, HPA038522: AB_2676059" "unprognostic (4.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.84e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (7.30e-2)" "unprognostic (3.22e-3)" "unprognostic (2.36e-1)" "prognostic favorable (1.86e-5)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-13)" "unprognostic (1.32e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (1.09e-2)" 18.1 23.8 101.7 11.9 119.4 2.7 18.0 116.6 121.1 39.5 65.1 43.3 7.0 43.5 4.3 14.9 38.3 11.4 42.0 123.3 105.3 21.5 3.8 22.5 13.9 123.9 106.0 39.2 16.3 21.4 61.3 8.6 135.0 23.7 4.7 23.3 13.4 25.9 42.3 12.2 19.2 33.2 109.4 13.8 19.4 12.7 112.1 28.9 19.1 54.0 11.1 31.2 23.5 152.9 0.0 14.9 50.6 22.8 26.7 27.4 0.2 24.6 41.7 41.2 51.4 26.4 10.3 0.0 3.6 44.3 36.9 0.5 44.4 7.5 19.4 27.8 33.7 0.3 9.3 0.9 19.3 0.2 9.9 24.8 1.9 19.4 2.9 35.3 51.7 1.2 1.1 0.7 15.3 0.5 0.5 0.1 18.3 0.8 15.5 0.2 2.0 0.2 1.7 0.2 68.1 37.6 3.6 3.0 15.9 15.2 2.1 3.4 22.8 4.2 24.8 27.5 5.0 13.8 6.8 2.0 21.1 0.0 14.3 8.4 1.7 0.3 23.2 1.5 25.2 6.7 32.5 30.2 1.7 16.2 85.6 51.7 1.6 16.5 0.6 0.3 48.7 29.9 101.7 119.4 116.6 121.1 123.3 105.3 123.9 106.0 135.0 109.4 112.1 152.9 9.6 19.2 5.4 22.9 7.5 5.0 12.1 3.6 12.0 45.8 6.6 5.7 50.5 11.5 5.4 5.5 22.9 0.4 4.6 1.1 25.4 18.2 5.6 7.6 9.5 13.9 19.3 4.0 47.1 4.2 0.7 15.2 4.6 2.3 1.3 10.8 15.7 3.3 1.2 40.4 44.8 1.2 0.0 1.9 4.0 13.1 9.6 1.8 8.8 7.5 3.2 24.7 9.2 49.3 102.3 8.0 1.7 19.2 1.4 8.3 0.4 21.6 17.3 20.1 6.6 10.0 17.3 6.9 13.7 3.2 2.8 0.8 20.1 7.0 1.3 5.4 APBB2 "FE65L, FE65L1, MGC35575" ENSG00000163697 "Amyloid beta precursor protein binding family B member 2" Q92870 4 40810027-41216714 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.9" "Group enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 586.1;Oligodendrocytes: 803.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "naive B-cell: 5.6" "Lineage enriched" "Detected in single" 14 "B-cells: 5.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 138.7;TIME: 192.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023542 Approved Approved Mitochondria No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA023542: AB_1844909" "unprognostic (4.43e-2)" "unprognostic (4.40e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (5.91e-3)" "unprognostic (8.13e-2)" "unprognostic (5.77e-2)" "unprognostic (4.00e-3)" "unprognostic (2.51e-1)" "unprognostic (1.21e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (2.19e-3)" "unprognostic (9.35e-3)" "unprognostic (3.92e-2)" "unprognostic (2.29e-2)" "unprognostic (2.61e-1)" 41.6 9.1 23.1 5.4 42.3 8.6 25.1 38.1 24.5 16.1 3.7 13.9 8.3 14.0 5.9 8.9 13.1 16.1 21.5 20.6 30.6 16.5 14.7 18.6 7.4 42.9 39.6 32.1 10.8 8.5 8.5 17.6 39.5 8.7 7.7 15.7 8.6 9.8 28.7 12.6 7.0 14.9 25.2 14.8 11.3 8.5 36.7 13.2 33.6 21.7 5.6 10.7 13.1 72.9 19.4 9.4 20.6 28.8 64.9 50.7 45.2 38.5 45.8 14.0 24.5 34.1 40.2 33.9 20.7 16.5 44.5 5.6 36.5 49.4 25.0 1.1 7.3 0.4 23.5 21.1 65.0 19.2 1.1 76.7 24.6 42.5 43.0 58.2 138.7 19.0 1.1 0.7 86.1 16.3 6.3 3.6 17.1 9.8 17.9 50.9 58.6 38.4 19.9 8.9 27.2 15.4 11.7 6.6 6.9 23.7 17.2 2.2 192.3 20.1 59.5 13.8 61.1 8.1 18.5 41.2 20.7 30.8 24.6 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 5.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 23.1 42.3 38.1 24.5 20.6 30.6 42.9 39.6 39.5 25.2 36.7 72.9 58.8 80.1 14.5 46.7 5.0 10.7 3.8 10.4 7.4 7.6 25.5 13.6 22.5 12.8 6.3 9.2 6.2 14.4 0.5 5.2 7.9 3.8 14.5 5.6 32.8 39.4 3.0 5.3 121.3 6.4 2.8 25.2 12.8 7.5 1.3 13.5 47.2 13.8 3.2 62.2 171.3 4.0 16.2 4.0 6.7 23.1 35.8 2.5 7.2 164.9 0.1 9.3 0.0 586.1 803.4 6.2 6.7 37.2 0.2 2.7 5.5 6.3 4.0 7.6 59.2 43.2 51.4 3.8 10.8 7.3 11.9 6.0 1.2 24.0 7.4 3.6 APCDD1 B7323 ENSG00000154856 "APC down-regulated 1" Q8J025 18 10454635-10489949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 129.8" "Cell type enhanced" "Detected in many" "Astrocytes: 120.5;Cholangiocytes: 85.8;Endometrial stromal cells: 429.5;Melanocytes: 80.0;Oligodendrocyte precursor cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 32.0;BJ hTERT+: 70.4;HaCaT: 43.0;HHSteC: 18.9;HSkMC: 39.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (1.21e-1)" "unprognostic (2.85e-2)" "unprognostic (1.11e-1)" "prognostic favorable (6.39e-4)" "prognostic favorable (8.23e-4)" "unprognostic (5.61e-3)" "unprognostic (6.79e-3)" "unprognostic (1.24e-1)" "unprognostic (5.59e-3)" "unprognostic (2.59e-2)" "unprognostic (3.14e-1)" "unprognostic (7.77e-2)" "unprognostic (2.04e-3)" "unprognostic (1.77e-1)" "unprognostic (3.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" 52.5 14.2 33.4 6.9 31.1 0.4 31.4 30.4 34.3 35.6 17.0 12.8 3.5 32.7 15.6 27.7 32.6 21.9 32.0 39.5 33.0 6.2 1.4 13.2 1.2 33.0 36.9 33.0 8.9 3.4 3.2 26.9 29.8 33.3 13.2 1.6 10.6 14.1 7.3 129.8 14.5 10.6 26.6 4.1 23.8 2.7 33.8 2.2 5.3 18.5 4.7 36.6 35.5 29.6 0.0 0.0 32.0 0.0 5.4 0.0 0.1 2.4 70.4 3.1 4.9 0.1 0.1 0.0 0.0 13.0 0.0 43.0 0.3 0.0 3.3 0.0 1.6 0.1 0.2 0.7 18.9 0.0 0.0 39.3 1.4 6.1 0.0 0.0 0.5 0.0 0.0 0.1 3.1 2.1 1.8 0.5 5.2 15.3 0.0 0.9 0.0 1.2 0.0 0.4 0.8 0.3 0.0 0.0 3.6 2.0 0.0 0.4 0.0 3.8 0.0 0.0 0.3 0.4 0.0 0.1 0.2 0.0 4.8 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.2 33.4 31.1 30.4 34.3 39.5 33.0 33.0 36.9 29.8 26.6 33.8 29.6 3.1 0.0 12.6 120.5 0.4 65.6 3.6 3.6 11.4 4.1 14.1 20.4 4.2 85.8 2.7 3.7 0.0 2.4 1.7 0.1 0.0 11.2 0.7 28.7 429.5 47.1 3.6 0.0 0.2 0.4 0.4 64.4 0.5 10.9 1.3 0.4 1.8 0.2 1.3 0.0 2.1 1.1 2.0 0.3 35.0 0.8 8.7 3.3 80.0 67.5 1.3 0.2 0.0 110.1 15.3 0.2 0.0 37.6 1.6 11.7 0.1 0.1 5.9 2.2 26.3 18.7 28.1 0.3 1.4 13.1 53.8 1.0 4.2 1.3 1.4 4.5 APCS "MGC88159, PTX2, SAP" ENSG00000132703 "Amyloid P component, serum" P02743 1 159587826-159588865 "Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "liver: 3629.2" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 4141.9" "Cancer enriched" "Detected in some" 25 "liver cancer: 826.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB007817, HPA053294" Supported "Secreted to blood" NA NA 27700000000 39000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "CAB007817: AB_598185, HPA053294: AB_2682104" "unprognostic (3.19e-3)" "unprognostic (2.30e-2)" 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 47.7 0.2 0.0 0.0 1.3 3629.2 0.1 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 388.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.8 0.0 0.0 0.0 2.7 0.0 45.5 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 57.8 4141.9 0.0 0.0 0.0 0.0 0.0 88.9 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 APELA "ELA, Ende, tdl" ENSG00000248329 "Apelin receptor early endogenous ligand" P0DMC3 4 164877178-164898965 "Predicted secreted proteins" "Angiogenesis, Differentiation, Gastrulation" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.2;prostate: 4.2" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 28.2;Proximal tubular cells: 28.5;Syncytiotrophoblasts: 40.9" "Cancer enhanced" "Detected in some" "prostate cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "NTERA-2: 41.7;SuSa: 25.1" "Secreted in other tissues" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.97e-2)" "unprognostic (6.97e-2)" "unprognostic (9.83e-4)" "unprognostic (8.92e-3)" "unprognostic (1.43e-3)" "unprognostic (4.50e-2)" "unprognostic (2.21e-1)" "unprognostic (1.71e-1)" "unprognostic (3.38e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-2)" "unprognostic (1.89e-1)" "unprognostic (4.34e-1)" "unprognostic (8.35e-2)" "unprognostic (1.95e-4)" 0.0 0.0 0.0 0.2 0.0 0.2 1.5 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 2.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 4.2 0.0 0.2 0.1 0.0 0.1 1.1 0.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 0.1 0.0 8.1 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 3.2 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 5.7 4.3 0.3 0.0 0.0 1.8 0.0 28.2 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 28.5 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 40.9 0.1 0.1 0.0 0.3 APLN "apelin, XNPEP2" ENSG00000171388 Apelin Q9ULZ1 X 129645259-129654956 "Predicted secreted proteins" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;placenta: 54.0" "Cell type enriched" "Detected in some" 7 "Endothelial cells: 68.2" "Group enriched" "Detected in all" 6 "glioma: 44.2;renal cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 6 "HUVEC TERT2: 502.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.50e-1)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.50e-2)" "unprognostic (5.94e-2)" "prognostic unfavorable (9.32e-4)" "prognostic unfavorable (6.09e-4)" "unprognostic (4.71e-2)" "unprognostic (2.25e-1)" "unprognostic (3.30e-1)" "unprognostic (9.12e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (1.55e-1)" "unprognostic (1.15e-1)" "unprognostic (2.26e-1)" "unprognostic (8.42e-2)" 4.7 9.2 19.9 2.2 21.2 0.0 3.0 19.0 24.0 0.6 6.8 1.0 0.8 0.7 0.3 0.6 1.2 0.4 12.6 15.4 23.8 7.5 1.4 13.4 0.1 30.1 25.9 2.4 0.3 1.0 5.4 54.0 25.4 1.1 0.3 0.3 0.6 0.5 3.7 1.5 0.8 1.9 29.7 0.7 1.2 1.1 33.6 0.3 0.9 1.1 0.2 3.4 0.4 35.8 0.2 0.6 58.5 0.5 1.9 3.6 0.0 0.2 0.0 1.1 1.8 0.0 0.0 0.0 6.2 0.2 2.5 0.0 1.4 14.1 1.0 0.0 0.1 0.0 0.6 0.1 0.2 3.3 1.4 7.7 0.1 7.2 0.0 0.0 502.1 1.7 0.1 1.9 2.6 0.0 0.2 0.7 1.5 0.0 26.8 0.3 0.5 0.9 0.0 0.0 2.0 6.2 0.2 0.1 0.0 0.1 0.1 0.9 86.2 2.1 0.2 36.5 2.1 0.8 0.0 0.0 34.0 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 21.2 19.0 24.0 15.4 23.8 30.1 25.9 25.4 29.7 33.6 35.8 3.0 0.0 1.3 8.1 0.0 0.1 0.1 0.6 0.0 0.0 0.2 9.4 6.8 0.0 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.2 0.0 0.1 0.1 68.2 0.0 0.0 0.1 0.0 0.7 1.0 0.0 0.2 1.3 0.0 0.0 0.3 0.3 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.2 1.8 1.9 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.4 0.6 0.0 0.2 0.0 0.1 1.2 0.2 2.9 0.0 0.0 APLP2 "APPH, APPL2" ENSG00000084234 "Amyloid beta precursor like protein 2" Q06481 11 130068147-130144811 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 249.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039319 Approved Approved Vesicles NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA039319: AB_10673141" "unprognostic (2.83e-2)" "unprognostic (1.29e-1)" "unprognostic (2.06e-1)" "unprognostic (3.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.86e-2)" "unprognostic (2.33e-1)" "unprognostic (2.70e-2)" "unprognostic (3.12e-3)" "unprognostic (7.44e-2)" "prognostic favorable (1.33e-9)" "unprognostic (3.20e-3)" "unprognostic (4.95e-2)" "prognostic favorable (2.90e-4)" "unprognostic (4.42e-2)" 217.2 130.2 125.6 144.0 126.0 196.5 192.3 164.7 157.9 170.4 252.6 209.9 272.4 176.6 138.6 134.2 167.6 201.8 271.6 131.0 153.2 359.9 334.8 391.4 77.5 130.9 137.5 180.8 136.0 291.5 87.1 324.8 133.1 287.7 176.7 540.8 135.3 291.0 65.9 113.3 226.6 211.5 135.4 95.7 149.7 54.9 157.9 81.5 607.8 85.2 56.8 199.1 129.6 152.8 216.7 170.3 307.1 281.2 1259.7 847.8 393.7 598.6 741.1 294.2 251.8 1300.5 1541.3 107.9 1515.3 1422.2 322.4 540.4 229.1 567.6 168.0 165.6 206.4 180.9 116.7 502.9 191.9 556.7 363.8 566.4 367.8 244.5 469.5 1520.2 912.7 34.1 180.7 228.9 495.2 205.7 26.9 245.3 182.8 256.8 301.1 70.0 69.8 105.5 758.9 589.6 109.9 239.0 706.9 368.0 92.0 535.8 582.2 489.5 1567.6 314.1 211.7 496.8 281.9 33.8 50.6 245.5 347.0 487.7 221.0 55.1 249.3 65.3 17.9 122.2 13.5 16.3 12.7 17.0 110.1 44.8 9.4 12.6 160.8 15.6 94.6 10.5 20.0 149.5 125.6 126.0 164.7 157.9 131.0 153.2 130.9 137.5 133.1 135.4 157.9 152.8 239.6 942.3 550.3 37.9 74.4 106.7 175.4 497.0 78.6 967.9 252.9 183.1 262.0 254.5 460.6 404.6 706.8 798.1 72.0 354.2 52.8 305.5 13.6 211.0 191.3 220.3 92.8 156.3 99.0 107.1 130.3 253.5 86.6 432.8 103.5 109.6 127.1 498.2 652.4 240.6 133.5 159.8 463.9 287.6 214.3 13.8 167.4 405.5 96.0 54.4 293.1 396.1 56.7 45.8 31.6 276.5 220.7 214.4 45.5 190.1 352.0 244.9 258.3 729.0 190.7 148.9 207.7 182.8 240.4 81.6 109.4 927.3 58.8 165.9 161.5 215.4 APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 314.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 325.4;Hepatocytes: 251.1;Syncytiotrophoblasts: 751.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 680.7;NK-cells: 343.8;T-cells: 367.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 130000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA012863: AB_1845683, HPA064700: AB_2685328" "unprognostic (4.07e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-2)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (6.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.99e-3)" "unprognostic (8.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.51e-2)" 168.0 44.6 59.2 47.2 60.1 187.4 84.6 76.0 65.4 41.8 62.2 46.5 32.7 46.8 106.3 26.7 46.0 43.1 37.5 64.1 72.6 50.5 314.0 53.2 44.0 61.4 62.8 40.8 45.2 83.4 78.7 80.2 68.6 44.2 42.9 32.0 40.1 47.9 39.5 55.8 34.7 49.2 60.5 66.6 38.5 54.2 69.7 42.4 209.1 24.4 34.1 51.8 29.5 68.8 110.6 191.3 90.0 139.5 175.3 97.5 94.4 141.8 153.4 133.3 137.4 113.7 189.3 45.9 161.1 170.6 232.1 198.1 85.0 165.1 149.1 62.3 69.7 51.2 66.0 226.9 140.9 99.5 115.4 134.3 226.9 154.9 107.0 173.8 192.5 73.4 61.5 195.8 128.6 168.1 68.9 108.2 59.3 166.6 172.1 56.3 312.8 96.3 140.2 98.9 150.6 59.4 146.9 240.5 157.1 92.0 87.6 78.8 173.7 156.9 140.6 134.7 209.5 113.0 134.3 50.9 83.1 148.0 151.9 61.8 99.3 198.9 367.9 98.6 228.8 36.4 100.8 268.2 102.1 37.4 78.6 202.2 680.7 343.8 71.3 50.7 75.0 363.3 59.2 60.1 76.0 65.4 64.1 72.6 61.4 62.8 68.6 60.5 69.7 68.8 28.5 19.2 32.7 25.8 22.2 24.3 46.7 77.6 17.1 51.4 48.1 32.1 17.5 34.3 39.7 49.7 10.4 325.4 163.2 18.9 17.6 72.0 22.9 18.0 26.3 42.4 18.0 33.6 24.0 45.4 50.6 40.6 15.3 23.8 36.1 68.6 41.4 251.1 95.9 16.8 25.4 19.4 85.5 50.0 94.8 32.5 65.0 59.5 46.2 42.2 105.1 35.0 222.5 19.6 15.9 40.8 25.4 82.0 54.9 34.1 20.8 13.2 24.5 22.5 39.5 36.9 33.2 97.1 90.1 16.7 20.0 751.1 96.7 38.3 28.0 28.1 APOA1 ENSG00000118137 "Apolipoprotein A1" P02647 11 116835751-116837622 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Amyloidosis, Atherosclerosis, Cancer-related genes, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 19248.5" "Group enriched" "Detected in many" 21 "Hepatocytes: 27332.1;Proximal enterocytes: 18348.1" "Cancer enriched" "Detected in many" 48 "liver cancer: 4515.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 17 "Hep G2: 3460.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016778, HPA046715" Supported Approved Vesicles,Cytosol "Secreted to blood" NA NA 1450000000000 110000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles Cytosol "CAB016778: , HPA046715: AB_2679768" "unprognostic (1.88e-3)" "unprognostic (4.53e-2)" "unprognostic (7.46e-2)" "unprognostic (4.00e-3)" "unprognostic (3.70e-2)" "unprognostic (1.41e-1)" "prognostic favorable (5.05e-4)" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (9.60e-3)" "unprognostic (1.59e-3)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.67e-8)" "unprognostic (3.46e-3)" "unprognostic (1.15e-1)" "unprognostic (6.24e-2)" "unprognostic (9.54e-2)" 3.2 1.4 1.2 3.6 1.2 0.0 2.1 1.1 1.4 0.8 0.8 7.4 1709.3 3.5 0.4 1.1 6.1 1.7 67.2 1.0 1.1 3.7 19248.5 2.7 3.2 1.1 1.1 23.1 2.5 0.0 4.2 1.6 1.1 1.1 0.2 0.1 0.7 1.0 0.8 1.0 4053.7 2.1 1.1 9.0 14.6 384.5 1.2 0.9 3.7 0.2 0.1 0.5 1.5 1.2 0.0 0.0 0.6 0.1 0.0 0.0 15.0 0.0 0.0 0.0 0.0 203.4 0.3 3.1 6.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.1 7.3 1.9 3460.4 0.0 16.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.0 0.2 0.3 15.0 1.2 1.2 0.1 0.5 15.0 20.3 0.0 2.6 5.7 20.7 8.9 0.0 0.0 3.9 0.0 0.1 2.6 0.0 0.4 2.1 0.1 1.2 0.2 4.9 0.0 5.5 0.2 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.5 0.2 0.1 0.2 0.5 0.0 0.2 0.0 1.2 0.6 0.1 1.2 1.2 1.1 1.4 1.0 1.1 1.1 1.1 1.1 1.1 1.2 1.2 2.0 3.2 3.3 0.3 49.7 0.1 0.5 0.2 0.6 0.5 0.9 0.9 37.0 479.0 1.3 0.0 0.0 0.6 5.1 0.4 0.0 0.1 36.9 15.2 4.3 50.3 1.8 541.9 0.5 1.1 4.2 5.8 17.9 1.7 2.5 419.2 458.7 27332.1 3.3 0.0 0.8 458.8 0.0 681.2 2.0 149.7 22.4 2.1 0.0 0.0 0.0 0.3 3.1 0.0 0.3 0.3 458.2 4.9 1.0 0.1 18348.1 9.0 0.4 0.6 6.6 1.6 13.0 39.8 11.2 0.0 0.6 4.2 35.7 1051.7 175.7 0.3 APOA2 ENSG00000158874 "Apolipoprotein A2" P02652 1 161222292-161223631 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction, Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1388 "liver: 36012.6" "Cell type enriched" "Detected in some" 75 "Hepatocytes: 50065.8" "Cancer enriched" "Detected in many" 329 "liver cancer: 11230.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "Hep G2: 16822.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025885, HPA072575" Supported "Secreted to blood" NA NA 115000000000 92000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB025885: , HPA072575: " "unprognostic (2.05e-1)" "unprognostic (4.70e-2)" "unprognostic (1.12e-1)" "unprognostic (2.99e-1)" "unprognostic (9.82e-2)" "unprognostic (1.92e-1)" "unprognostic (3.16e-1)" "unprognostic (2.79e-1)" "unprognostic (1.57e-2)" "unprognostic (4.40e-3)" "unprognostic (3.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.60e-1)" "unprognostic (6.09e-2)" 3.8 1.1 0.7 0.7 0.6 25.9 1.8 0.5 1.4 0.9 1.0 0.7 0.0 0.7 0.1 1.0 1.9 0.0 2.0 0.6 0.8 9.5 36012.6 2.1 0.3 1.1 0.8 0.7 2.0 0.0 1.2 1.3 1.1 0.6 0.5 0.0 0.6 0.0 0.6 0.9 0.9 0.0 0.8 7.7 1.9 1.2 0.7 0.4 0.8 0.0 0.3 0.4 0.8 1.0 0.0 0.6 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 1814.4 0.0 3.6 0.0 0.0 0.0 2.3 1.5 0.0 0.0 0.0 0.0 5.8 10.0 16822.4 0.0 19.3 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.9 0.2 0.0 0.0 0.7 0.7 1.5 0.0 1.1 1.3 14.6 0.3 0.0 11.3 0.8 0.0 7.8 0.0 0.2 5.2 0.1 0.0 4.1 0.0 0.1 0.0 0.0 3.8 0.0 5.2 0.0 6.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.0 0.0 0.7 0.6 0.5 1.4 0.6 0.8 1.1 0.8 1.1 0.8 0.7 1.0 0.0 0.0 0.0 0.0 40.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 480.4 0.0 0.0 0.0 0.8 0.0 0.1 1.9 0.0 1.7 0.0 0.0 22.5 0.0 323.6 0.0 0.6 6.4 0.2 0.0 0.0 0.0 0.0 425.9 50065.8 4.7 0.0 0.0 0.2 0.0 665.8 0.0 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.1 9.8 0.0 0.0 0.0 0.0 0.0 1.9 0.9 0.0 0.0 5.6 26.0 0.0 0.0 0.0 APOA4 ENSG00000110244 "Apolipoprotein A4" P06727 11 116820700-116823304 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 3112.4" "Cell type enriched" "Detected in some" 44 "Proximal enterocytes: 10311.5" "Cancer enriched" "Detected in some" 29 "liver cancer: 291.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.7;CACO-2: 8.0;Hep G2: 7.7;NB-4: 7.3;RPMI-8226: 12.5;SH-SY5Y: 10.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001352, HPA002549, CAB068250, CAB068251, CAB068252" Enhanced Approved Vesicles "Secreted to blood" NA NA 61200000000 74000000000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB068250: AB_2665657, CAB068251: AB_2665659, CAB068252: AB_2665658, HPA001352: AB_1078179, HPA002549: AB_1078177" "unprognostic (8.81e-2)" "unprognostic (2.12e-2)" "unprognostic (1.75e-2)" "unprognostic (7.91e-2)" 0.3 0.0 0.0 2.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.9 2204.9 1.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 257.2 0.0 2.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3112.4 3.0 0.0 0.1 4.6 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 3.1 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 77.5 0.0 0.0 0.0 234.3 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 221.5 0.0 0.0 0.0 10311.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 87.7 0.0 APOA5 "APOA-V, RAP3" ENSG00000110243 "Apolipoprotein A5" Q6Q788 11 116789367-116792420 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 216 "liver: 582.1" "Cell type enriched" "Detected in some" 88 "Hepatocytes: 1249.5" "Cancer enriched" "Detected in single" 489 "liver cancer: 112.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 55 "Hep G2: 35.6" "Not detected" "Not detected" "Secreted to blood" NA NA 114000000 21000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.57e-4)" "unprognostic (4.67e-3)" "unprognostic (5.57e-2)" "unprognostic (2.60e-3)" "unprognostic (2.40e-1)" "unprognostic (2.31e-4)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 582.1 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 35.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 10.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 11.4 1249.5 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 APOB ENSG00000084674 "Apolipoprotein B" P04114 2 21001429-21044073 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 143 "intestine: 304.3;liver: 1191.0" "Group enriched" "Detected in some" 8 "Hepatocytes: 2967.4;Proximal enterocytes: 1585.9" "Cancer enriched" "Detected in some" 99 "liver cancer: 295.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 30 "Hep G2: 1079.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016070, HPA049793" Supported Supported Vesicles,Cytosol "Secreted to blood" NA NA 1490000000000 100000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "CAB016070: AB_626690, HPA049793: AB_2680885" "unprognostic (1.63e-2)" "unprognostic (2.71e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (1.04e-2)" "unprognostic (7.31e-2)" "unprognostic (1.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.43e-2)" "unprognostic (8.89e-3)" "unprognostic (3.01e-1)" "unprognostic (4.59e-3)" "unprognostic (3.60e-3)" "unprognostic (2.89e-2)" "unprognostic (2.38e-1)" "unprognostic (2.99e-1)" "unprognostic (6.23e-2)" 2.7 0.0 0.1 0.2 0.2 0.1 0.9 0.1 0.1 0.7 0.2 0.4 181.4 0.2 0.0 0.1 0.1 0.5 5.2 0.1 0.3 0.3 1191.0 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.1 0.1 0.5 304.3 0.2 0.2 0.5 0.3 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1079.8 0.0 0.6 0.1 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.5 0.6 0.0 0.6 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.2 0.3 0.2 0.2 0.3 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 277.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 1.6 3.5 0.0 104.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 52.8 2967.4 0.1 0.0 0.2 30.8 0.0 69.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.5 1.5 0.0 0.0 1585.9 0.6 0.0 0.0 0.0 1.1 0.2 0.5 0.3 0.0 0.0 0.0 3.9 0.9 14.5 0.0 APOC1 ENSG00000130208 "Apolipoprotein C1" P02654 19 44914247-44919349 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 16232.1" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 33405.9" "Cancer enriched" "Detected in all" 21 "liver cancer: 3253.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 5.6" "Lineage enriched" "Detected in single" 12 "dendritic cells: 5.6" "Cell line enhanced" "Detected in many" "Hep G2: 576.4;HSkMC: 332.9;K-562: 151.6;SK-MEL-30: 268.0" "Low region specificity" "Detected in all" HPA051518 Supported "Secreted to blood" NA NA 20300000000 15000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA051518: AB_2681519" "unprognostic (3.51e-2)" "unprognostic (3.31e-3)" "unprognostic (1.14e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.15e-7)" "unprognostic (9.51e-3)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (1.11e-1)" "unprognostic (2.52e-1)" "unprognostic (7.13e-3)" "unprognostic (3.48e-3)" "unprognostic (1.65e-1)" "unprognostic (2.01e-3)" "unprognostic (1.65e-1)" 59.2 1998.1 90.3 28.1 133.0 52.2 87.1 83.3 338.1 29.0 73.6 29.1 13.1 11.0 42.0 5.9 21.2 31.0 10.9 75.3 109.8 14.6 16232.1 289.9 140.1 133.2 152.8 56.4 21.4 16.3 23.6 41.7 121.9 14.4 16.7 15.1 35.5 2.2 22.2 73.1 49.1 4.0 92.7 254.9 22.7 18.7 139.2 37.4 36.3 6.1 33.9 23.5 11.3 169.4 2.7 26.5 12.0 5.0 37.1 38.2 111.5 1.3 1.7 4.8 7.3 55.6 49.9 8.4 9.4 1.0 3.2 1.8 15.6 1.9 2.3 0.4 63.5 36.8 4.2 576.4 32.9 27.5 18.1 332.9 2.8 4.8 1.8 9.2 1.3 1.8 151.6 0.8 1.7 3.6 1.5 2.0 112.4 10.4 5.6 6.2 16.0 0.8 7.3 2.0 5.3 3.3 18.9 0.3 268.0 37.7 2.2 98.4 4.2 0.4 1.7 0.2 1.7 4.5 5.4 8.2 0.7 7.4 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.3 90.3 133.0 83.3 338.1 75.3 109.8 133.2 152.8 121.9 92.7 139.2 169.4 22.9 115.4 214.4 2.3 40.6 17.0 4.1 5.8 6.2 2.5 49.8 92.8 0.8 453.2 55.8 1.8 0.0 31.7 1.6 2.4 49.0 4.6 1.2 6.6 128.4 68.9 2.4 768.8 0.3 4.0 341.3 93.0 19.4 5.0 142.6 30.6 432.6 33405.9 4789.8 0.0 0.5 3.2 4.1 867.7 27.3 22.8 270.9 620.5 30.2 3.7 124.5 276.0 0.0 0.0 0.0 3.2 0.3 259.5 1.3 4.2 0.6 16.6 24.4 9.9 19.7 1628.8 24.4 2.0 3.2 3.7 17.8 71.6 46.7 1226.7 2.1 5.0 APOC2 ENSG00000234906 "Apolipoprotein C2" P02655 19 44946035-44949565 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Disease variant, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 83 "liver: 9641.4" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 1170.2" "Cancer enriched" "Detected in some" 17 "liver cancer: 49.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 30 "NK-cells: 3.2" "Group enriched" "Detected in many" 4 "Hep G2: 713.0;THP-1: 1354.4" HPA055877 Supported "Secreted to blood" NA NA 43000000000 49000000000 "Cluster 48: NK-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA055877: AB_2682953" "unprognostic (4.28e-2)" "unprognostic (7.73e-3)" "unprognostic (1.33e-1)" "unprognostic (3.66e-2)" "unprognostic (8.91e-2)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (1.96e-2)" "unprognostic (2.86e-1)" "unprognostic (1.15e-2)" "unprognostic (5.14e-8)" "unprognostic (1.32e-1)" "unprognostic (1.45e-1)" "unprognostic (1.77e-2)" "unprognostic (9.80e-3)" 1.2 5.4 49.5 1.7 55.2 1.1 5.3 55.1 116.2 4.5 44.7 4.3 41.4 1.2 4.8 2.4 4.3 3.7 0.8 50.7 69.2 16.3 9641.4 34.9 15.8 65.3 64.9 0.4 2.2 6.6 3.0 2.9 74.3 1.3 4.4 2.8 2.4 2.1 1.9 4.3 65.6 0.7 63.3 3.9 2.7 1.1 59.9 3.2 0.9 0.7 9.9 2.2 0.8 75.0 2.9 0.6 0.3 0.4 0.5 0.6 1.3 0.1 0.0 0.0 0.1 2.0 2.8 0.7 0.3 0.0 0.0 2.6 0.0 0.1 0.0 0.7 0.1 123.0 2.7 713.0 0.2 15.4 237.5 0.2 0.3 0.0 0.0 0.3 0.0 0.1 1.7 2.9 0.1 0.8 0.9 126.3 0.5 3.2 0.4 0.8 5.2 1.1 0.0 1.5 0.1 0.1 1.9 0.2 7.7 0.0 0.7 1354.4 0.0 0.3 0.6 0.8 0.8 2.3 0.9 2.2 0.2 3.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 49.5 55.2 55.1 116.2 50.7 69.2 65.3 64.9 74.3 63.3 59.9 75.0 0.1 0.0 2.3 0.0 1.2 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.1 11.5 0.0 3.7 0.0 0.1 0.1 0.0 3.9 0.0 0.0 0.0 0.1 0.3 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 26.0 0.0 13.6 1170.2 33.8 0.0 0.0 0.4 0.0 15.5 1.2 0.0 0.0 24.0 7.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 10.0 0.7 0.0 0.1 17.7 32.3 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.4 0.3 1.8 0.0 1.3 0.0 APOC3 ENSG00000110245 "Apolipoprotein C3" P02656 11 116829706-116833072 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "liver: 27649.0" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 84691.9" "Cancer enriched" "Detected in many" 643 "liver cancer: 4021.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "CACO-2: 107.3;Hep G2: 296.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA065365, HPA073918" Supported Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Secreted to blood" NA NA 106000000000 45000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "Nucleoli, Cell Junctions" "HPA065365: AB_2732733, HPA073918: " "prognostic favorable (3.77e-4)" "unprognostic (2.33e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (1.60e-2)" "unprognostic (5.21e-2)" 4.1 1.2 0.0 1.0 0.0 0.0 2.5 0.0 0.1 0.4 0.0 7.2 907.0 0.5 0.0 1.1 1.9 0.0 1.6 0.0 0.0 18.2 27649.0 1.4 0.9 0.0 0.0 0.8 2.4 0.0 0.8 0.9 0.0 0.6 0.0 0.0 0.6 0.0 0.6 1.2 1106.7 0.5 0.0 8.0 1.5 1.0 0.0 0.5 0.8 0.2 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.0 0.1 107.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 296.2 0.0 10.7 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 2.3 0.2 0.0 0.0 0.0 6.3 3.9 0.0 0.1 1.1 3.8 4.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.2 0.0 3.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 67.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 674.9 0.0 0.0 0.0 0.2 0.0 0.0 3.9 0.0 4.2 0.0 0.0 39.7 0.0 823.7 0.0 0.4 1.5 0.1 0.0 0.0 0.0 0.3 707.9 84691.9 1.1 0.0 0.0 264.5 0.0 1107.4 0.0 12.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.0 0.0 0.0 0.0 10473.3 121.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 39.8 0.0 135.5 0.0 APOC4 ENSG00000267467 "Apolipoprotein C4" P55056 19 44942237-44945496 "Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 208 "liver: 629.1" "Cell type enriched" "Detected in single" 37 "Hepatocytes: 3.8" "Cancer enriched" "Detected in single" 15 "liver cancer: 0.7" "Region enhanced" "Detected in single" "white matter: 3.0" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 2.4;TIME: 1.2" "Not detected" "Not detected" HPA062671 Approved "Secreted to blood" NA NA 1000000000 980000000 "Cluster 6: Non-specific - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA062671: AB_2684828" "unprognostic (1.82e-3)" 0.2 0.3 0.4 0.0 0.8 0.5 0.2 0.5 0.9 0.0 0.0 0.1 0.0 0.4 0.7 0.0 0.2 0.3 0.2 0.2 0.5 0.0 629.1 0.2 0.1 0.5 0.4 0.3 0.0 0.2 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.4 0.1 1.2 0.5 0.0 0.0 0.0 0.1 0.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.2 0.1 0.5 0.3 2.4 0.0 0.3 0.0 1.2 0.1 0.0 0.1 0.0 0.1 0.3 0.4 0.0 0.4 0.0 0.6 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.0 0.1 0.1 0.4 0.0 0.0 0.4 0.8 0.5 0.9 0.2 0.5 0.5 0.4 0.4 0.3 0.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 APOD ENSG00000189058 "Apolipoprotein D" P05090 3 195568705-195584033 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 5037.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 4485.3;Leydig cells: 2077.4;Melanocytes: 1028.1;Peritubular cells: 994.5" "Cancer enriched" "Detected in all" 4 "melanoma: 925.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "memory B-cell: 5.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.0" "Group enriched" "Detected in many" 6 "ASC diff: 3507.4;ASC TERT1: 1918.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040520 Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 98900000000 90000000000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA040520: AB_2677020" "prognostic favorable (5.51e-4)" "unprognostic (7.62e-3)" "unprognostic (7.85e-3)" "unprognostic (3.34e-3)" "unprognostic (2.20e-1)" "unprognostic (1.02e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.38e-1)" "unprognostic (3.19e-1)" "unprognostic (6.90e-3)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.71e-3)" 2071.8 84.8 949.6 13.9 1157.3 0.9 5037.8 1174.9 1364.1 620.2 1370.1 144.7 56.0 496.7 155.7 160.0 750.6 213.3 1007.8 952.8 1010.4 49.7 7.1 183.5 24.6 1148.3 1040.5 131.2 212.4 61.9 192.2 350.5 1122.0 419.8 57.2 0.8 1272.3 183.8 1154.9 970.1 88.4 96.2 1027.5 8.2 402.6 75.7 1070.2 113.5 828.8 625.3 20.8 434.4 591.7 1347.6 0.0 2.2 0.5 0.7 3507.4 1918.1 6.1 31.3 7.6 0.1 0.2 222.4 0.4 0.4 0.9 1.8 0.0 0.9 0.4 10.5 0.3 0.3 2.4 0.3 0.2 0.1 12.5 0.3 0.5 91.4 21.0 0.2 17.0 0.3 4.3 0.2 0.2 0.9 5.3 1.3 0.1 0.7 0.5 38.9 0.5 0.1 0.0 0.6 0.0 2.8 0.7 0.5 0.0 34.8 31.8 1.3 67.2 0.1 0.4 0.5 1.4 0.4 0.1 0.2 0.3 9.2 1.0 0.4 420.3 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 949.6 1157.3 1174.9 1364.1 952.8 1010.4 1148.3 1040.5 1122.0 1027.5 1070.2 1347.6 543.2 0.0 11.0 2.9 7.5 145.0 16.0 25.4 46.7 0.0 121.6 138.7 26.9 1.5 81.8 5.5 0.0 5.4 15.9 1.4 0.0 0.4 9.7 16.3 393.7 114.1 46.3 0.0 3.3 0.0 4.2 4485.3 7.7 7.0 0.0 0.0 21.4 0.0 13.3 0.0 2.1 0.7 10.2 0.3 193.2 51.0 2077.4 31.8 1028.1 279.2 1.0 0.0 0.0 300.6 221.5 2.3 0.3 994.5 19.2 25.7 0.0 0.2 128.9 0.0 19.7 100.3 210.7 10.5 4.0 24.1 102.6 5.9 23.5 7.0 0.6 47.3 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 APOF ENSG00000175336 "Apolipoprotein F" Q13790 12 56360568-56362857 "Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 344 "liver: 416.7" "Cell type enriched" "Detected in some" 21 "Hepatocytes: 341.9" "Cancer enriched" "Detected in some" 6 "liver cancer: 34.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "Hep G2: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 18000000000 2200000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (3.55e-2)" "unprognostic (1.13e-1)" "unprognostic (1.48e-2)" "unprognostic (8.99e-3)" "unprognostic (9.84e-2)" "unprognostic (3.29e-2)" "unprognostic (2.08e-3)" "unprognostic (7.84e-2)" "unprognostic (4.22e-1)" "unprognostic (5.69e-2)" "unprognostic (2.68e-3)" "unprognostic (8.55e-2)" "unprognostic (2.42e-2)" "unprognostic (2.77e-1)" "unprognostic (5.57e-2)" "unprognostic (2.87e-1)" "unprognostic (4.43e-2)" 0.0 0.0 0.3 0.1 0.2 0.2 0.1 0.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 416.7 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.4 4.3 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.2 0.2 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.2 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.2 0.7 0.3 0.2 0.0 0.3 0.1 0.3 0.0 0.2 1.1 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.3 8.6 0.0 0.0 2.1 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.4 0.0 16.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 5.0 341.9 0.0 0.0 0.0 0.1 0.0 10.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.1 0.0 0.8 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.3 APOH "B2G1, BG" ENSG00000091583 "Apolipoprotein H" P02749 17 66212033-66256525 "Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 563 "liver: 17965.3" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 7680.6" "Cancer enriched" "Detected in many" 232 "liver cancer: 2878.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "Hep G2: 1253.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA001654, HPA003732, CAB022214" Enhanced Supported "Golgi apparatus" "Secreted to blood" NA NA 247000000000 41000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "CAB022214: , HPA001654: AB_1078181, HPA003732: AB_1078183" "unprognostic (2.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.39e-7)" "unprognostic (1.26e-1)" "unprognostic (5.99e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (1.10e-6)" "unprognostic (1.26e-2)" "unprognostic (5.76e-2)" 0.9 0.3 0.0 0.1 0.1 0.4 0.2 0.1 0.2 0.2 0.3 0.8 2.5 0.1 1.0 0.2 0.8 2.8 0.6 0.2 0.0 31.9 17965.3 5.6 0.3 0.2 0.1 0.2 10.9 0.0 0.2 0.4 0.1 0.2 0.7 0.2 0.1 0.3 0.1 0.2 1.0 0.0 0.1 4.3 3.8 0.3 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.0 33.5 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 60.8 0.0 1.4 0.1 0.0 1.7 1.1 0.0 0.0 0.0 0.4 0.0 2.6 1.4 1253.3 0.0 6.4 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.1 1.4 0.5 0.2 0.0 0.2 0.1 0.6 31.5 0.0 0.8 6.4 0.1 0.0 0.9 0.4 0.0 3.4 0.1 0.2 0.0 0.0 0.0 1.7 0.2 0.1 0.1 0.0 0.8 0.1 2.9 15.3 2.4 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 12.3 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 183.0 0.6 0.0 0.0 0.0 0.0 0.2 3.9 0.8 0.2 0.2 0.0 5.2 0.0 109.7 0.2 2.3 0.6 0.0 0.0 0.1 0.0 0.0 120.0 7680.6 0.5 0.0 0.2 0.4 0.0 182.4 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.8 0.0 0.0 0.0 0.4 25.6 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 8.8 0.0 0.8 0.0 APOL1 APOL ENSG00000100342 "Apolipoprotein L1" O14791 22 36253071-36267530 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 220.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 106.1;Glandular and luminal cells: 216.2;Hepatocytes: 115.6;Pancreatic endocrine cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 243.9;HDLM-2: 166.1;HHSteC: 120.3;RPTEC TERT1: 91.1;RT4: 146.8" "HPA018885, CAB056156" Supported "Secreted to blood" NA NA 1640000000 9200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "CAB056156: AB_2665576, HPA018885: AB_1844953" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (8.98e-3)" "unprognostic (1.67e-1)" "unprognostic (8.28e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (4.41e-2)" "unprognostic (1.58e-1)" "unprognostic (4.07e-3)" "unprognostic (5.15e-2)" "prognostic unfavorable (7.43e-6)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (5.05e-3)" "prognostic favorable (2.01e-5)" 45.3 15.8 8.1 62.5 8.2 4.2 28.4 7.8 9.8 53.8 9.4 32.0 32.7 38.8 17.7 25.7 36.7 69.0 29.5 7.4 8.4 44.5 220.5 59.5 23.1 10.0 8.5 24.8 9.0 4.9 14.1 53.0 9.6 37.5 27.2 0.9 29.7 52.2 11.7 7.1 28.9 65.4 9.0 56.8 64.9 7.9 10.8 24.9 18.0 13.8 23.6 117.7 29.9 8.2 21.6 5.1 0.1 0.6 46.8 44.6 14.2 2.3 9.0 13.7 38.6 0.6 34.4 7.0 243.9 24.8 31.3 5.3 0.0 19.2 3.6 166.1 0.2 6.1 3.2 41.4 120.3 2.4 20.2 8.3 1.7 38.0 0.8 2.0 27.3 1.3 23.8 85.1 2.4 0.2 8.5 2.1 0.6 0.6 0.2 13.6 2.6 3.2 91.1 146.8 1.9 0.1 10.9 5.8 2.1 0.3 0.8 7.8 24.7 29.5 12.4 3.2 1.5 6.5 4.0 1.6 16.0 12.4 4.6 15.6 6.1 5.5 12.6 6.8 10.7 2.6 8.1 11.2 4.3 1.4 4.6 6.3 16.1 22.4 10.3 0.5 5.4 7.2 8.1 8.2 7.8 9.8 7.4 8.4 10.0 8.5 9.6 9.0 10.8 8.2 37.4 57.7 34.3 0.3 7.2 1.7 21.4 73.5 2.8 0.5 6.3 3.0 3.6 15.7 67.1 18.4 2.1 11.0 12.6 31.2 0.0 37.8 0.8 106.1 48.8 41.3 7.7 3.8 0.1 20.0 8.2 27.3 45.9 216.2 11.4 4.3 49.6 115.6 9.1 0.0 0.1 17.7 32.6 15.8 5.3 1.4 27.4 10.9 0.0 7.5 19.4 0.1 36.0 0.0 0.0 105.1 19.9 24.0 15.0 31.2 20.5 2.1 60.5 1.3 6.6 5.5 10.6 0.4 0.4 3.4 2.3 6.7 12.9 1.6 4.6 62.5 APOL3 "APOLIII, CG12-1" ENSG00000128284 "Apolipoprotein L3" O95236 22 36140330-36166177 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 59.1;Endothelial cells: 69.8;Hepatic stellate cells: 69.7;Kupffer cells: 38.7;NK-cells: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 34.1;ASC TERT1: 54.1;HDLM-2: 25.6;Karpas-707: 59.0" "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "prognostic favorable (6.82e-4)" "unprognostic (5.93e-3)" "unprognostic (6.79e-2)" "unprognostic (2.70e-2)" "unprognostic (2.22e-1)" "unprognostic (7.05e-2)" "unprognostic (6.30e-2)" "unprognostic (2.67e-1)" "unprognostic (8.94e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (7.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" 58.2 12.3 10.1 25.4 10.0 10.1 43.7 8.7 12.2 17.2 7.6 16.3 15.0 18.8 12.3 12.0 24.4 14.3 33.7 8.8 9.1 19.0 39.9 42.0 43.4 11.4 10.1 9.6 6.3 3.4 8.5 16.3 10.0 18.4 11.4 0.6 15.7 14.9 16.6 19.6 21.7 16.0 8.8 47.6 12.3 2.9 10.8 18.1 25.2 19.6 20.8 17.6 19.5 8.7 4.3 0.0 0.0 0.1 34.1 54.1 1.8 1.8 10.2 3.1 7.0 0.0 9.5 2.1 0.4 5.0 4.6 0.7 0.0 1.3 1.9 25.6 0.0 9.2 1.3 2.1 18.3 0.1 2.6 11.4 0.0 9.0 0.4 2.1 22.1 2.0 0.2 59.0 1.1 0.1 11.7 0.3 0.1 0.0 0.5 16.9 0.0 1.3 0.3 3.0 0.2 0.1 6.0 4.2 0.1 0.0 0.0 1.2 16.2 1.5 0.6 1.7 0.5 15.6 10.8 0.1 3.7 3.5 1.5 8.3 19.1 0.8 16.9 23.4 27.3 9.7 14.4 17.5 15.4 8.0 13.4 14.3 2.3 18.5 24.6 0.5 14.7 17.2 10.1 10.0 8.7 12.2 8.8 9.1 11.4 10.1 10.0 8.8 10.8 8.7 59.1 3.2 8.6 1.6 21.1 5.0 4.3 3.9 2.2 0.0 5.8 4.2 7.9 8.6 4.3 3.7 0.0 1.9 16.0 0.3 0.0 2.5 0.9 1.8 4.7 69.8 0.0 20.6 0.0 1.6 1.2 18.8 7.1 1.3 9.5 2.0 69.7 20.6 6.9 0.0 0.0 7.5 2.0 38.7 10.6 1.4 24.2 19.6 3.6 9.4 29.2 0.7 46.4 0.0 0.0 3.0 0.1 9.8 15.3 10.4 5.3 2.8 4.2 0.3 13.1 3.2 10.1 0.2 0.3 4.1 4.1 0.8 31.5 4.3 2.3 4.7 APOL4 APOLIV ENSG00000100336 "Apolipoprotein L4" Q9BPW4 22 36189124-36204840 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 32.7;Enteroendocrine cells: 14.9;Glandular and luminal cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6;myeloid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;monocytes: 1.6" "Cell line enhanced" "Detected in some" "BEWO: 18.7;HDLM-2: 109.9;HSkMC: 16.1;K-562: 23.7;SCLC-21H: 47.9" "HPA049797, HPA055435" Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Vesicles "HPA049797: AB_2680887, HPA055435: AB_2682816" "unprognostic (2.73e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.51e-1)" "unprognostic (5.31e-1)" "unprognostic (3.39e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "prognostic favorable (3.45e-4)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (2.00e-5)" "unprognostic (4.26e-2)" "unprognostic (3.69e-1)" "unprognostic (4.18e-2)" "prognostic favorable (2.40e-6)" 13.5 1.0 0.8 6.0 0.8 1.5 14.7 0.9 2.2 4.6 0.5 3.3 4.8 3.9 1.6 4.3 5.9 6.3 5.3 0.9 1.6 8.1 2.0 12.8 4.7 2.5 1.3 3.9 1.0 0.3 9.4 3.3 1.9 14.7 3.4 0.1 5.8 3.4 1.1 4.1 3.8 2.4 1.0 3.2 4.9 0.7 1.1 2.9 3.2 1.3 1.8 12.1 3.6 0.8 0.0 0.0 0.0 0.0 0.2 2.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 109.9 0.0 5.7 0.0 0.0 0.1 0.0 0.2 16.1 0.0 0.0 0.0 0.0 0.8 0.0 23.7 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 1.0 47.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.3 0.1 0.2 1.6 0.0 0.0 0.9 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.8 0.8 0.9 2.2 0.9 1.6 2.5 1.3 1.9 1.0 1.1 0.8 7.0 0.0 6.7 0.3 0.2 1.3 0.7 1.5 0.0 0.3 4.6 2.2 1.1 1.5 3.4 0.0 0.0 0.5 0.1 0.0 3.9 0.2 0.0 32.7 12.4 6.6 14.9 4.2 0.0 0.7 1.0 10.4 0.0 52.6 2.5 0.0 2.5 0.4 2.3 1.7 0.1 0.8 0.0 6.2 6.5 0.0 2.8 8.8 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 1.2 0.2 0.3 4.2 0.0 0.0 9.0 1.9 0.0 0.0 0.0 1.1 6.2 1.3 0.5 0.4 1.9 APOM "G3a, NG20" ENSG00000204444 "Apolipoprotein M" O95445 6 31652416-31658210 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 390.7" "Group enriched" "Detected in many" 8 "Hepatocytes: 665.9;Proximal tubular cells: 681.1" "Cancer enriched" "Detected in all" 13 "liver cancer: 185.9" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "basophil: 3.0" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 12 "Hep G2: 38.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034086, HPA051006" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 7400000000 8200000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "CAB034086: AB_1119033, HPA051006: AB_2681307" "unprognostic (2.76e-3)" "unprognostic (1.69e-2)" "unprognostic (8.66e-2)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (5.28e-2)" "unprognostic (3.78e-1)" "unprognostic (1.97e-2)" "unprognostic (1.80e-1)" "unprognostic (6.04e-3)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (7.28e-2)" "unprognostic (5.71e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-1)" "unprognostic (3.20e-2)" 4.9 5.3 0.6 0.1 0.6 2.5 5.2 1.0 0.9 3.7 0.5 3.8 0.6 3.9 1.0 4.1 4.1 0.5 3.5 0.6 0.7 93.7 390.7 2.6 0.6 0.7 0.7 6.2 6.0 0.7 4.7 0.1 0.7 3.8 0.4 0.4 3.5 0.5 7.2 6.4 9.0 0.4 0.7 4.1 5.3 16.0 0.6 1.2 5.5 0.6 1.1 3.3 3.3 0.8 0.5 0.3 0.6 0.7 0.6 0.8 0.0 0.4 1.1 0.4 0.9 3.2 1.0 1.4 0.2 1.1 0.2 0.6 0.4 0.6 0.8 0.8 0.7 0.8 0.3 38.2 1.3 1.7 0.1 1.2 0.4 0.3 1.0 0.5 0.3 0.9 1.2 0.4 1.1 1.1 1.1 0.9 0.5 0.6 0.2 0.8 0.4 1.5 1.1 0.6 0.5 0.2 0.4 0.0 0.5 0.2 1.5 1.2 0.4 0.2 0.1 0.3 0.3 1.1 1.2 1.5 0.2 1.8 0.1 3.0 0.6 0.6 0.3 0.3 0.5 1.1 0.4 0.3 0.5 0.5 0.5 0.6 0.4 0.3 0.7 0.3 0.7 0.3 0.6 0.6 1.0 0.9 0.6 0.7 0.7 0.7 0.7 0.7 0.6 0.8 1.5 0.0 7.4 2.3 9.0 6.4 6.7 6.7 9.1 1.5 6.6 12.4 1.6 12.8 3.0 14.7 4.2 2.0 1.6 4.1 76.3 4.3 60.2 5.2 3.1 2.0 4.2 11.4 0.3 6.9 0.9 4.3 5.1 1.6 5.1 1.8 8.9 665.9 5.4 0.0 0.4 4.9 2.0 14.5 4.2 38.4 9.3 6.1 5.4 0.0 2.5 14.6 1.0 0.5 1.3 6.4 4.9 6.4 7.4 4.2 81.4 681.1 4.6 2.5 0.0 6.2 3.1 33.1 6.6 5.3 6.5 1.2 5.6 4.6 6.5 6.1 APOO "FAM121B, MGC4825, Mic23, MIC26, MICOS26, My025" ENSG00000184831 "Apolipoprotein O" Q9BUR5 X 23833353-23907938 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 180.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003187 Supported Approved Mitochondria,Cytosol "Secreted to blood" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA003187: AB_1079375" "unprognostic (2.53e-2)" "prognostic favorable (3.77e-4)" "unprognostic (4.86e-2)" "unprognostic (6.38e-3)" "unprognostic (3.45e-1)" "unprognostic (2.42e-1)" "unprognostic (6.18e-2)" "unprognostic (2.95e-1)" "unprognostic (6.45e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.22e-1)" "prognostic favorable (2.56e-6)" "unprognostic (2.53e-2)" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (5.88e-3)" 9.0 23.7 55.8 9.0 58.0 7.9 13.3 58.1 76.3 13.1 67.8 17.3 14.4 10.6 19.6 12.6 20.8 9.3 65.1 57.9 58.4 46.5 18.2 8.6 11.7 58.8 57.0 9.4 14.2 62.0 29.2 10.9 57.3 13.7 18.8 52.8 19.7 15.0 45.9 7.7 12.0 12.0 57.0 8.4 17.7 16.8 56.8 14.0 20.3 73.2 11.6 11.2 8.1 57.1 36.5 32.7 53.9 37.8 8.8 19.9 8.3 17.9 21.9 37.4 38.8 19.3 17.0 31.5 21.9 16.5 48.5 29.3 68.5 35.7 41.2 33.4 48.7 15.9 28.6 31.1 20.8 40.9 17.1 22.2 20.7 41.2 30.4 20.1 26.6 38.8 22.9 33.2 35.1 34.6 41.2 43.0 49.2 47.5 52.7 31.5 26.6 75.6 74.1 18.4 36.4 26.5 39.0 36.7 39.7 52.4 63.6 17.9 6.5 23.9 14.6 86.6 27.9 26.3 50.5 28.7 38.5 19.8 35.8 14.8 4.8 1.4 12.6 15.9 16.6 10.8 13.7 12.5 14.0 10.2 10.9 10.7 3.0 10.3 16.0 16.6 14.0 7.7 55.8 58.0 58.1 76.3 57.9 58.4 58.8 57.0 57.3 57.0 56.8 57.1 7.4 16.0 11.5 61.7 11.8 14.0 17.0 74.3 11.4 20.4 14.3 17.0 61.8 21.5 28.3 23.9 14.6 17.2 11.3 12.8 180.0 28.4 25.9 56.0 13.0 10.1 7.2 20.8 61.4 16.0 8.9 11.7 13.3 24.4 3.8 14.2 7.9 13.9 22.7 20.2 76.5 17.0 44.7 14.6 12.0 15.7 11.5 9.9 28.4 74.0 34.2 50.0 8.2 43.7 76.5 10.2 20.0 15.8 14.8 14.1 24.0 80.6 106.9 32.4 6.6 10.8 22.3 26.1 53.2 18.9 7.0 12.4 9.5 17.0 22.3 16.8 APOOL "AAIR8193, CXorf33, FAM121A, Mic27, MICOS27, UNQ8193" ENSG00000155008 "Apolipoprotein O like" Q6UXV4 X 85003877-85093316 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000612 Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA000612: AB_1078594" "prognostic unfavorable (2.68e-5)" "unprognostic (2.72e-2)" "unprognostic (6.16e-2)" "unprognostic (5.71e-3)" "unprognostic (4.27e-3)" "unprognostic (1.47e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (8.35e-2)" "unprognostic (1.10e-1)" "unprognostic (2.77e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.35e-12)" "unprognostic (2.67e-2)" "unprognostic (5.65e-2)" "unprognostic (7.11e-2)" "unprognostic (7.51e-2)" 5.9 6.5 2.8 3.7 3.2 3.7 6.6 3.6 5.2 4.3 5.4 5.9 5.9 4.4 4.7 6.2 5.1 4.0 11.5 4.2 3.9 11.2 14.5 4.3 3.3 4.5 4.3 4.1 6.0 11.6 3.2 4.1 4.6 5.9 6.5 6.8 5.8 4.4 17.8 6.7 4.6 5.9 2.9 3.5 6.8 2.2 4.6 3.6 8.3 17.9 3.5 4.2 4.0 4.3 11.4 6.5 6.0 8.2 16.9 11.7 6.4 7.4 6.9 6.2 6.0 7.0 6.3 8.3 6.9 8.4 11.7 8.8 18.3 7.0 9.3 8.4 8.0 8.8 10.2 7.2 11.0 17.5 9.1 11.8 11.8 10.4 18.4 7.2 8.8 10.7 15.2 10.7 10.8 6.1 7.2 7.1 4.9 6.8 12.1 7.9 14.6 8.6 7.8 8.3 0.6 9.8 14.1 12.7 8.8 6.4 7.7 8.3 9.2 8.5 8.3 17.5 8.6 6.9 24.4 7.1 10.9 12.4 7.3 2.4 2.0 0.6 1.9 2.8 1.7 2.1 1.7 1.4 2.1 1.9 2.1 2.0 0.4 1.2 2.5 2.6 1.0 1.0 2.8 3.2 3.6 5.2 4.2 3.9 4.5 4.3 4.6 2.9 4.6 4.3 16.7 16.0 19.1 25.8 10.7 5.6 13.3 5.3 6.2 26.7 16.8 11.9 45.4 15.7 7.7 20.2 14.6 15.3 9.3 10.6 13.7 18.1 0.2 17.0 15.4 13.0 37.1 14.9 32.3 14.0 11.3 13.9 17.3 17.4 21.5 18.3 15.0 51.6 12.0 21.9 26.2 15.3 4.1 15.2 2.3 0.8 13.7 11.4 0.0 21.5 9.5 13.6 8.2 30.2 36.2 17.5 14.6 15.4 8.7 19.6 15.6 43.7 7.6 16.8 19.7 19.3 16.9 3.1 8.2 11.5 3.4 19.4 6.6 16.8 15.4 17.8 ARAP1 CENTD2 ENSG00000186635 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1" Q96P48 11 72685069-72793599 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020703, HPA070383" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 36000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "CAB020703: , HPA070383: AB_2686262" "unprognostic (3.60e-2)" "unprognostic (7.68e-2)" "unprognostic (6.19e-2)" "unprognostic (5.98e-2)" "unprognostic (5.76e-2)" "unprognostic (1.64e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (4.01e-2)" "unprognostic (4.07e-1)" "unprognostic (5.95e-2)" "prognostic favorable (2.04e-5)" "unprognostic (1.84e-1)" "unprognostic (1.05e-3)" "unprognostic (6.93e-2)" "unprognostic (2.57e-2)" "prognostic favorable (6.41e-4)" "unprognostic (7.56e-3)" 41.5 63.5 40.0 58.6 48.6 97.5 33.4 37.9 50.4 44.1 62.9 35.5 29.6 38.9 14.0 37.7 48.3 44.2 42.9 42.2 38.5 47.8 40.2 71.8 53.4 50.6 42.3 49.4 37.1 20.4 48.9 35.5 45.9 44.9 18.2 8.6 33.3 25.7 20.1 47.1 43.3 28.7 40.1 117.5 31.3 16.4 50.8 32.2 46.6 20.1 25.2 39.7 37.5 56.8 19.7 41.9 15.2 18.5 63.4 42.9 23.1 26.2 46.5 29.8 29.3 56.0 50.8 42.9 51.3 44.4 40.7 64.5 23.2 64.4 12.5 50.9 28.4 36.6 40.3 81.9 43.7 25.1 98.7 47.5 65.4 48.7 23.4 36.2 33.2 31.3 31.5 17.4 13.9 40.3 38.9 89.3 9.5 35.1 25.9 36.8 23.2 21.3 27.5 61.1 15.7 32.0 19.1 27.9 84.8 19.5 25.1 56.8 37.5 41.0 28.5 42.8 16.4 27.4 14.3 23.0 21.8 37.4 22.3 19.3 24.8 30.7 8.9 39.4 5.2 6.6 5.9 6.8 15.9 4.7 4.5 5.4 50.8 13.4 51.3 5.3 6.7 17.6 40.0 48.6 37.9 50.4 42.2 38.5 50.6 42.3 45.9 40.1 50.8 56.8 8.9 28.9 32.3 33.6 16.1 7.4 7.5 14.3 15.4 4.3 8.7 7.9 2.6 7.2 9.0 16.5 33.3 9.2 18.3 16.5 9.8 13.5 50.1 14.1 11.7 7.8 23.3 9.9 7.7 7.5 8.9 22.4 16.3 9.1 10.8 36.9 9.7 10.8 43.0 0.0 7.0 12.8 12.2 45.6 25.1 6.4 20.8 57.3 8.8 30.0 29.0 7.4 21.6 17.6 31.5 12.1 10.9 15.1 12.3 4.8 20.9 5.3 20.2 2.8 0.0 8.6 8.8 0.4 2.8 10.8 5.4 4.9 12.4 10.5 15.1 7.4 ARCN1 COPD ENSG00000095139 "Archain 1" P48444 11 118572390-118603033 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037573, HPA044874" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 140000 "Cluster 18: Basophils - Vesicular transport" "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Golgi apparatus, Cytosol" "HPA037573: AB_10696938, HPA044874: AB_2679126" "unprognostic (1.46e-2)" "unprognostic (4.97e-2)" "unprognostic (1.66e-1)" "unprognostic (3.20e-1)" "unprognostic (9.99e-2)" "unprognostic (2.30e-2)" "prognostic unfavorable (2.97e-5)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-3)" "unprognostic (9.39e-2)" "unprognostic (3.56e-2)" "unprognostic (7.99e-2)" "unprognostic (9.20e-2)" "unprognostic (4.14e-3)" "unprognostic (5.56e-3)" 75.4 67.7 47.5 53.8 51.0 30.4 67.5 52.0 60.5 78.0 61.2 65.0 59.2 69.2 111.1 72.5 60.5 51.6 75.6 46.8 50.9 58.3 91.6 62.6 53.2 51.2 51.3 65.5 119.7 61.9 88.7 54.7 51.1 68.8 67.1 39.2 79.6 64.5 51.1 60.9 64.9 71.0 50.0 57.9 71.8 46.2 50.5 58.8 65.2 55.0 62.2 66.4 60.9 57.2 90.9 72.6 135.3 98.9 174.0 172.7 66.6 244.8 208.5 102.4 120.7 239.4 116.6 96.4 199.7 275.7 148.0 123.7 160.5 139.5 151.5 128.0 66.3 211.6 56.7 151.4 197.1 140.4 121.8 157.8 117.6 175.0 168.7 149.3 162.2 95.0 106.8 139.2 201.3 157.0 123.2 130.8 85.3 207.7 92.4 107.9 134.2 147.4 137.3 107.0 88.3 86.6 130.2 129.0 70.1 132.5 155.9 111.4 144.0 129.4 65.1 118.4 109.5 79.9 78.5 147.6 74.3 122.6 161.4 118.1 49.8 50.7 52.7 59.8 69.0 39.5 51.7 51.3 54.0 35.4 48.0 44.7 41.5 64.5 64.5 44.9 53.9 55.8 47.5 51.0 52.0 60.5 46.8 50.9 51.2 51.3 51.1 50.0 50.5 57.2 43.6 35.3 47.9 12.4 32.2 31.6 38.5 31.5 23.9 22.4 39.4 27.9 46.5 24.3 41.9 31.3 4.2 17.2 45.6 68.4 9.8 34.3 11.1 38.4 72.2 43.1 40.2 14.9 15.4 37.8 36.1 44.9 39.3 50.4 39.3 31.9 31.4 55.7 30.3 18.5 17.7 80.2 22.4 36.0 37.6 8.5 48.1 35.3 23.2 11.2 49.0 17.3 26.8 17.1 20.2 46.9 35.8 41.3 68.3 51.5 56.2 30.5 46.2 13.6 19.7 52.7 45.7 44.8 47.6 30.4 34.7 30.2 38.4 43.9 42.6 51.6 AREL1 "FIEL1, KIAA0317" ENSG00000119682 "Apoptosis resistant E3 ubiquitin protein ligase 1" O15033 14 74653437-74713117 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051306 Uncertain NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "HPA051306: AB_2681433" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (1.76e-1)" "unprognostic (1.92e-3)" "unprognostic (1.29e-1)" "unprognostic (2.49e-2)" "unprognostic (1.58e-3)" "unprognostic (9.32e-2)" "unprognostic (1.09e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (2.12e-1)" "prognostic favorable (4.67e-6)" "unprognostic (6.73e-2)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" "unprognostic (7.18e-2)" 6.2 6.9 4.3 10.4 4.7 16.9 6.7 3.1 4.8 7.8 3.3 10.4 11.8 6.5 7.1 10.0 10.4 6.7 10.6 6.7 5.0 14.6 5.3 9.0 10.0 3.1 4.1 6.8 9.5 15.4 4.5 8.3 2.6 8.4 12.3 13.3 9.7 7.7 9.9 7.8 12.7 8.4 3.7 8.5 9.8 17.1 5.6 13.1 15.5 13.1 13.3 10.0 5.6 3.5 19.2 24.6 25.1 23.6 21.3 14.1 19.3 20.7 23.5 25.2 25.1 19.2 22.2 16.4 10.8 26.6 22.9 25.3 26.9 23.2 32.4 30.4 12.7 25.5 14.5 13.7 14.2 18.5 23.9 18.4 15.8 18.6 20.0 31.6 25.0 23.5 20.3 17.1 32.9 25.8 19.2 7.8 15.4 26.0 24.2 19.5 28.4 10.2 20.5 42.6 24.6 33.0 18.1 23.9 13.4 16.6 21.0 18.5 34.6 23.8 28.5 14.3 24.3 22.6 32.8 32.2 28.8 14.0 18.8 2.2 3.5 7.1 4.6 5.1 3.3 2.1 2.8 4.2 4.5 1.4 2.9 2.6 6.8 3.4 2.7 2.1 2.6 3.4 4.3 4.7 3.1 4.8 6.7 5.0 3.1 4.1 2.6 3.7 5.6 3.5 3.7 12.8 4.6 23.2 6.5 3.6 3.4 6.0 7.4 12.3 7.0 3.7 11.1 5.7 7.5 11.0 27.1 4.2 11.2 18.3 1.9 6.6 3.1 7.2 7.1 5.0 14.9 21.0 24.8 9.2 3.3 4.6 12.8 10.5 1.3 10.3 6.4 12.9 8.0 16.8 24.1 11.6 8.2 15.0 5.3 4.6 8.7 9.6 5.4 23.4 13.9 5.2 11.3 22.6 32.5 11.2 6.5 6.8 9.1 6.8 11.8 5.1 7.3 11.7 0.0 4.4 4.9 6.7 11.1 10.5 3.3 5.9 8.4 6.4 11.5 6.3 ARFIP2 POR1 ENSG00000132254 "ADP ribosylation factor interacting protein 2" P53365 11 6474683-6481479 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032985, HPA038156" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli fibrillar center, Golgi apparatus" "CAB032985: AB_2058811, HPA038156: AB_10697243" "unprognostic (2.32e-1)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "prognostic favorable (2.00e-5)" "unprognostic (8.44e-2)" "unprognostic (1.25e-1)" "unprognostic (4.05e-3)" "unprognostic (2.50e-1)" "unprognostic (2.96e-1)" "unprognostic (1.76e-1)" "unprognostic (5.70e-3)" "unprognostic (3.11e-1)" "prognostic favorable (9.53e-4)" "unprognostic (2.05e-1)" "unprognostic (2.41e-1)" "unprognostic (2.32e-2)" "unprognostic (9.48e-3)" 19.8 29.3 31.7 18.6 32.3 22.8 50.7 32.5 35.2 36.3 36.2 36.8 32.9 27.2 34.0 31.4 39.3 23.9 17.9 32.1 31.4 27.0 34.6 24.4 22.4 31.2 31.4 29.4 49.4 46.4 40.7 29.7 31.9 46.6 48.1 28.3 57.7 28.2 15.2 32.8 30.7 27.4 30.9 20.7 50.4 18.3 31.8 25.7 36.9 16.1 32.0 29.2 24.4 33.1 50.4 64.8 38.9 38.5 59.1 53.9 56.1 40.3 107.0 86.2 101.8 62.1 80.3 39.9 16.5 79.3 49.8 68.0 49.4 84.1 70.0 30.9 86.5 22.3 87.7 60.4 71.3 36.2 42.8 60.0 65.7 43.0 98.3 64.2 55.9 38.3 35.3 45.0 55.8 98.9 41.9 41.6 67.2 119.0 71.9 31.7 22.6 37.1 61.9 50.4 50.8 63.2 48.7 204.9 25.9 36.3 86.9 33.0 36.8 35.4 35.7 39.1 30.3 67.3 32.5 24.3 65.4 22.0 43.9 13.0 15.6 9.9 17.9 10.9 17.8 12.1 16.7 14.5 21.3 13.8 16.7 17.1 6.1 21.1 6.7 16.6 18.9 13.9 31.7 32.3 32.5 35.2 32.1 31.4 31.2 31.4 31.9 30.9 31.8 33.1 14.8 6.4 6.4 4.6 20.7 28.0 49.3 48.9 16.5 32.6 59.8 45.1 4.3 40.0 30.5 12.9 29.2 80.1 24.3 56.0 58.7 62.7 31.7 28.1 20.1 19.6 63.0 21.8 8.4 85.4 65.8 23.1 62.2 37.2 31.8 30.3 20.3 21.1 28.1 21.9 7.8 126.6 32.6 10.1 16.4 43.3 20.5 14.4 24.9 5.6 25.2 35.4 18.6 6.6 7.6 59.9 63.4 24.5 28.0 73.3 65.2 34.4 34.7 32.3 26.3 21.6 23.3 41.0 26.2 26.2 32.1 112.5 16.9 40.9 52.6 64.7 ARHGAP36 FLJ30058 ENSG00000147256 "Rho GTPase activating protein 36" Q6ZRI8 X 131058346-131089885 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "adrenal gland: 105.4;brain: 144.3;pituitary gland: 176.9" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Breast glandular cells: 2.7;Oligodendrocyte precursor cells: 1.0;Skeletal myocytes: 1.5" "Cancer enriched" "Detected in some" 21 "thyroid cancer: 62.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 161 "SH-SY5Y: 176.9" "Region enhanced" "Detected in many" "hypothalamus: 89.4" "Low region specificity" "Detected in many" "HPA002064, HPA076209" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" Yes NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "Vesicles, Plasma membrane" "HPA002064: AB_1078891, HPA076209: " "unprognostic (2.92e-2)" "unprognostic (7.71e-9)" "unprognostic (2.19e-1)" "unprognostic (8.15e-2)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.73e-1)" "unprognostic (1.40e-2)" "unprognostic (1.34e-2)" "unprognostic (2.31e-1)" 0.2 105.4 20.1 0.0 3.7 0.0 1.4 0.8 3.2 1.6 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 13.5 132.5 0.0 0.0 0.0 0.0 35.0 46.1 0.0 0.0 0.0 176.9 0.1 144.3 0.2 0.1 0.0 0.2 0.0 6.6 0.1 0.0 0.0 4.7 0.0 0.1 0.8 52.1 0.4 0.1 1.1 0.0 0.0 0.1 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 176.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.1 3.7 0.8 3.2 13.5 132.5 35.0 46.1 144.3 4.7 52.1 10.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ARHGAP6 rhoGAPX-1 ENSG00000047648 "Rho GTPase activating protein 6" O43182 X 11117651-11665920 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 44.3;Microglial cells: 127.4;Oligodendrocyte precursor cells: 60.3;Prostatic glandular cells: 54.4;Sertoli cells: 46.0;Skeletal myocytes: 62.3;Smooth muscle cells: 44.4" "Cancer enhanced" "Detected in many" "prostate cancer: 12.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.2;ASC TERT1: 34.2;HEL: 36.4;HMC-1: 24.7;HSkMC: 33.8;K-562: 26.5;RT4: 20.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001798, HPA036779, HPA064390" Enhanced Supported Cytosol "Intracellular and membrane" NA NA 350000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA001798: , HPA036779: AB_10672229, HPA064390: AB_2685253" "unprognostic (2.36e-1)" "unprognostic (1.68e-2)" "unprognostic (3.49e-2)" "unprognostic (7.31e-2)" "unprognostic (6.34e-2)" "unprognostic (1.69e-2)" "unprognostic (4.70e-2)" "unprognostic (2.79e-1)" "unprognostic (1.70e-1)" "unprognostic (7.46e-4)" "unprognostic (1.53e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.60e-2)" "unprognostic (5.96e-2)" "unprognostic (1.28e-2)" "unprognostic (7.99e-4)" 10.8 1.1 9.0 1.7 5.1 0.7 5.6 2.0 4.2 7.6 3.2 13.9 2.1 10.5 8.2 3.8 8.4 4.2 4.0 5.0 5.8 6.5 0.9 9.6 1.2 3.2 4.0 16.4 1.9 1.2 3.2 7.0 3.2 27.6 3.9 1.0 2.6 30.9 9.6 2.5 4.7 12.9 2.6 5.9 4.1 1.9 6.1 1.0 25.4 8.1 0.8 10.4 5.7 3.8 0.0 0.0 2.4 0.0 26.2 34.2 0.6 0.4 0.6 1.4 0.9 0.4 0.0 0.0 0.0 5.0 0.0 0.1 0.9 0.0 1.2 0.6 0.5 36.4 0.4 0.0 9.7 0.1 24.7 33.8 0.0 2.5 0.1 3.1 0.7 0.1 26.5 12.3 1.5 0.0 0.0 0.2 0.7 0.2 0.4 0.1 11.6 15.7 8.3 20.3 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.4 0.3 1.6 0.7 7.1 0.2 0.7 0.0 0.0 0.5 0.2 4.0 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 9.0 5.1 2.0 4.2 5.0 5.8 3.2 4.0 3.2 2.6 6.1 3.8 9.6 0.0 1.7 10.4 5.3 2.0 16.9 0.3 2.8 4.3 2.3 3.3 4.7 0.0 2.6 33.1 0.0 0.6 0.4 0.0 25.4 0.0 0.1 0.1 5.1 9.2 1.2 2.1 5.5 1.1 0.7 29.1 3.6 0.2 40.0 3.0 8.2 0.0 4.9 0.0 44.3 0.4 0.0 2.2 18.9 0.9 16.1 29.1 5.4 127.4 3.4 7.2 0.0 60.3 3.5 0.7 0.0 10.1 4.9 54.4 0.0 7.4 5.6 0.7 46.0 62.3 44.4 0.2 0.4 4.5 1.7 0.0 1.2 2.1 0.0 22.3 ARHGEF1 "LBCL2, P115-RHOGEF, SUB1.5" ENSG00000076928 "Rho guanine nucleotide exchange factor 1" Q92888 19 41883173-41930150 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.4" "Cell type enhanced" "Detected in all" "dendritic cells: 156.2;NK-cells: 187.4;T-cells: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009502, HPA012924, HPA060784" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB009502: AB_667785, HPA012924: AB_1845000, HPA060784: AB_2684363" "prognostic favorable (5.92e-4)" "unprognostic (2.09e-1)" "unprognostic (8.29e-3)" "unprognostic (8.10e-3)" "unprognostic (7.63e-2)" "unprognostic (7.59e-3)" "unprognostic (4.99e-2)" "unprognostic (7.28e-2)" "unprognostic (5.88e-2)" "unprognostic (1.84e-2)" "unprognostic (6.59e-2)" "unprognostic (3.29e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (3.54e-1)" "unprognostic (1.95e-1)" "unprognostic (8.00e-2)" "unprognostic (4.65e-2)" 50.2 20.9 17.1 79.1 21.8 113.5 39.9 19.1 21.9 37.2 17.8 37.5 26.8 33.4 3.6 34.1 36.4 23.5 26.2 16.1 18.2 31.9 30.0 67.7 127.5 24.1 20.2 32.9 27.4 12.6 25.9 18.3 22.0 32.1 10.4 5.6 28.8 11.8 15.4 37.6 87.1 13.4 19.0 168.4 34.9 10.9 21.4 96.5 36.7 8.9 48.9 33.9 33.2 27.9 58.8 69.9 15.8 19.9 21.9 22.9 18.4 30.1 45.7 37.4 32.8 21.5 49.2 77.9 54.6 27.8 19.8 33.8 20.3 46.9 11.8 74.1 23.6 63.1 30.6 28.4 31.9 68.4 100.8 27.8 30.5 36.3 23.5 19.9 36.2 68.2 25.5 46.7 21.8 40.4 48.0 52.9 17.9 46.4 54.0 71.8 29.7 46.3 23.2 31.8 10.3 43.8 42.3 18.7 36.0 8.1 21.9 114.4 49.6 49.7 33.2 26.8 47.7 63.0 43.2 68.4 40.5 107.6 80.2 10.4 20.5 29.2 47.0 39.5 37.2 20.1 35.6 49.4 21.5 19.5 36.1 39.4 27.4 32.1 57.5 11.3 38.7 36.4 17.1 21.8 19.1 21.9 16.1 18.2 24.1 20.2 22.0 19.0 21.4 27.9 46.6 6.4 22.0 35.3 97.3 14.5 13.9 15.0 20.5 18.7 13.1 12.4 4.2 8.6 8.8 7.3 27.1 13.3 156.2 21.7 3.9 23.6 1.4 12.2 16.7 29.0 21.7 23.8 8.0 24.9 22.8 17.7 56.6 16.8 31.7 19.3 26.7 9.3 38.2 11.8 7.9 29.2 16.2 52.5 31.9 1.8 19.3 58.9 19.6 18.7 39.0 8.8 187.4 13.6 27.6 55.9 22.7 16.6 66.4 15.7 10.1 7.3 6.3 19.1 26.3 17.6 17.3 7.3 10.1 17.3 14.8 10.1 159.0 20.4 26.4 11.1 ARID2 "BAF200, DKFZp686G052, FLJ30619, KIAA1557" ENSG00000189079 "AT-rich interaction domain 2" Q68CP9 12 45729706-45908040 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 525.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063044 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA063044: AB_2684929" "unprognostic (8.41e-2)" "unprognostic (1.03e-1)" "unprognostic (4.02e-2)" "unprognostic (3.94e-2)" "unprognostic (4.15e-2)" "prognostic favorable (5.75e-4)" "unprognostic (1.26e-2)" "unprognostic (9.71e-2)" "unprognostic (9.04e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.47e-1)" "unprognostic (1.12e-2)" "unprognostic (9.21e-2)" "unprognostic (3.02e-1)" "unprognostic (2.00e-1)" "unprognostic (6.53e-2)" 6.4 5.2 4.6 6.7 7.8 12.6 7.5 13.8 6.9 8.5 10.2 6.8 5.0 6.9 6.5 8.4 6.4 5.4 6.0 5.0 7.3 6.3 5.4 7.8 7.5 7.8 6.4 8.3 7.2 11.7 5.0 7.2 7.6 7.4 6.0 13.2 6.7 6.2 5.9 10.0 6.6 6.1 6.0 6.9 6.2 26.1 6.2 18.7 8.8 7.7 8.9 6.8 8.0 9.8 10.3 14.5 25.3 11.1 10.5 7.3 13.7 7.0 9.9 9.6 8.9 20.7 10.4 19.8 12.7 9.8 7.0 12.1 20.6 11.8 13.6 8.8 9.8 26.1 15.9 10.1 7.2 20.7 11.5 6.0 8.8 12.1 19.1 13.4 10.0 29.1 22.4 19.9 8.6 13.4 29.9 14.7 15.1 0.0 7.7 22.9 18.0 19.0 9.1 16.9 13.6 17.4 11.4 13.0 11.1 14.5 20.0 40.8 11.8 10.3 12.3 7.0 9.2 13.2 11.8 53.6 7.9 53.2 7.4 9.4 1.1 2.7 2.4 1.3 2.5 1.0 2.1 2.5 1.5 1.1 2.0 1.9 1.4 2.1 3.4 3.3 2.0 0.9 4.6 7.8 13.8 6.9 5.0 7.3 7.8 6.4 7.6 6.0 6.2 9.8 23.3 28.9 28.4 110.4 30.8 33.8 14.4 16.3 36.5 51.6 21.7 15.4 15.6 14.3 17.3 29.5 68.8 15.5 49.0 21.3 7.9 13.2 525.4 23.2 23.8 21.1 21.0 35.1 56.7 10.0 10.5 22.0 24.5 27.7 22.1 29.3 19.2 17.3 11.2 32.0 60.3 19.0 22.4 29.8 36.7 149.3 24.8 25.6 14.2 128.4 22.4 19.9 45.3 144.3 157.9 18.8 24.6 22.6 33.8 23.7 19.1 7.4 15.4 66.2 26.3 27.0 27.2 80.2 17.0 39.3 41.3 23.4 34.8 16.4 17.9 21.0 ARL16 ENSG00000214087 "ADP ribosylation factor like GTPase 16" 17 81681187-81683797 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043711 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" "HPA043711: AB_10964639" "unprognostic (1.73e-2)" "unprognostic (1.92e-2)" "unprognostic (3.20e-1)" "unprognostic (5.73e-3)" "unprognostic (5.73e-2)" "unprognostic (1.24e-1)" "unprognostic (6.60e-3)" "unprognostic (1.05e-1)" "unprognostic (1.26e-2)" "unprognostic (3.23e-1)" "unprognostic (1.17e-2)" "unprognostic (5.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.44e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" 27.1 23.6 23.2 7.5 24.9 13.2 26.7 23.3 27.2 28.7 20.9 27.7 8.4 25.3 17.9 22.0 23.2 13.4 23.2 25.5 22.4 39.4 20.1 18.3 13.5 22.0 22.2 27.2 22.0 18.2 18.9 17.8 21.9 25.7 8.3 13.8 21.0 14.2 23.6 24.6 16.9 11.1 23.5 19.1 21.9 25.3 22.7 16.2 22.6 18.9 10.8 26.6 24.7 24.1 23.2 36.0 39.6 46.4 18.7 24.3 22.6 46.3 43.3 55.0 42.5 42.9 23.7 22.4 28.5 43.1 39.7 21.3 32.6 33.9 32.6 19.9 58.0 24.9 29.5 20.0 52.7 54.8 18.9 29.5 19.1 42.0 40.8 39.8 35.2 28.6 19.7 19.2 36.3 21.5 52.0 57.5 32.4 27.7 43.4 57.7 37.6 15.2 40.2 30.1 71.5 72.5 30.5 18.5 48.5 33.0 24.9 49.2 40.2 74.9 38.5 40.4 56.1 28.0 12.8 43.7 44.7 29.5 42.3 41.8 27.0 27.6 21.1 25.3 25.8 43.2 19.9 19.5 23.4 52.4 31.9 24.2 15.1 41.9 21.3 32.1 20.3 22.5 23.2 24.9 23.3 27.2 25.5 22.4 22.0 22.2 21.9 23.5 22.7 24.1 39.1 25.6 30.9 6.2 32.7 37.7 28.7 64.2 36.5 37.1 47.9 61.1 20.1 38.6 48.4 44.1 31.3 64.6 41.8 49.2 60.7 48.4 10.4 44.0 31.1 35.4 36.1 21.5 13.4 44.5 47.5 38.5 60.1 35.1 21.5 44.2 29.3 21.2 35.0 21.9 10.6 37.5 42.7 20.0 34.9 8.8 40.7 26.1 33.8 7.5 41.1 43.3 43.3 14.1 11.3 43.9 39.7 44.0 29.4 38.8 60.7 86.1 40.9 38.9 52.6 22.4 41.7 66.5 50.3 34.7 34.7 38.6 33.8 54.7 45.4 31.4 ARMC5 FLJ13063 ENSG00000140691 "Armadillo repeat containing 5" Q96C12 16 31458080-31467166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041524, HPA063706" Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "Focal adhesion sites" "HPA041524: AB_10796676, HPA063706: AB_2685098" "unprognostic (1.37e-1)" "unprognostic (1.68e-3)" "unprognostic (8.22e-3)" "unprognostic (9.96e-2)" "unprognostic (2.59e-1)" "unprognostic (2.94e-3)" "unprognostic (4.09e-2)" "unprognostic (6.14e-3)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" "prognostic favorable (1.97e-6)" "unprognostic (4.70e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-2)" "unprognostic (2.34e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" 6.3 7.9 9.0 3.4 9.2 21.4 4.3 8.9 11.7 6.0 7.0 5.8 4.6 6.9 0.9 9.9 5.6 2.0 6.5 9.2 8.1 8.7 24.6 4.6 3.2 12.3 9.4 6.8 6.4 3.0 9.0 2.1 12.4 7.7 0.9 2.4 5.3 2.2 16.0 8.5 7.0 1.7 9.1 8.8 6.8 6.8 9.2 2.9 9.7 3.9 1.3 5.6 6.6 10.5 5.0 7.6 3.3 4.8 2.0 1.5 8.4 6.5 2.8 3.6 3.0 7.2 5.0 4.9 13.3 3.5 3.6 7.5 3.9 5.7 0.7 6.8 9.9 2.2 12.4 16.7 4.0 14.9 14.3 3.7 6.3 3.6 1.0 4.2 5.5 8.0 11.2 11.5 2.5 12.2 5.6 59.5 5.3 2.2 5.0 10.0 4.7 18.2 2.9 5.6 10.7 9.4 5.9 7.8 4.6 2.0 5.1 17.6 10.9 7.8 5.7 3.2 5.4 10.4 9.8 3.0 5.1 12.2 5.7 2.9 2.3 0.7 3.2 1.1 2.7 2.7 2.5 2.6 3.0 2.2 2.2 2.6 1.3 7.1 1.3 7.2 3.2 2.6 9.0 9.2 8.9 11.7 9.2 8.1 12.3 9.4 12.4 9.1 9.2 10.5 8.7 6.4 14.3 4.2 6.2 6.5 9.2 8.7 9.1 6.0 6.3 5.0 5.8 11.5 8.2 0.0 6.2 7.5 7.6 11.1 3.9 5.0 1.2 5.2 8.6 10.8 7.8 8.2 4.3 4.4 5.4 6.1 6.6 7.6 9.5 6.7 8.9 28.7 6.1 13.5 4.0 8.7 6.1 3.7 4.0 0.6 4.4 6.7 1.8 2.8 3.9 7.2 6.2 2.0 4.6 4.4 3.8 5.7 8.0 6.9 9.2 4.6 3.4 5.9 0.0 8.7 6.6 5.5 8.0 9.6 6.3 11.5 7.6 6.1 7.7 6.1 ARMCX4 "CXorf35, GASP4, MGC40053" ENSG00000196440 "Armadillo repeat containing X-linked 4" Q5H9R4 X 101418287-101533459 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 66.6;Excitatory neurons: 59.1;Inhibitory neurons: 87.5;Microglial cells: 63.7;Oligodendrocyte precursor cells: 78.4;Oligodendrocytes: 75.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000429, HPA051930" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Vesicles "HPA000429: AB_1078210, HPA051930: AB_2681665" "unprognostic (1.92e-1)" "unprognostic (1.91e-1)" "unprognostic (1.07e-2)" "unprognostic (1.10e-2)" "unprognostic (6.91e-3)" "unprognostic (2.81e-3)" "unprognostic (7.28e-2)" "unprognostic (3.67e-4)" "unprognostic (2.33e-2)" "unprognostic (4.29e-1)" "prognostic favorable (8.20e-5)" "unprognostic (1.94e-2)" "unprognostic (1.40e-2)" "unprognostic (6.94e-3)" "unprognostic (1.69e-1)" "unprognostic (1.88e-1)" "unprognostic (4.92e-2)" 2.1 4.0 1.8 1.1 2.1 0.7 2.7 1.4 2.0 2.8 0.0 2.5 0.9 3.6 2.5 1.0 3.0 1.3 1.8 2.0 3.0 2.4 1.0 1.8 0.9 1.8 2.1 7.1 2.0 4.5 4.5 1.7 2.1 3.6 1.6 1.6 1.9 4.7 1.9 2.1 2.1 2.6 1.1 1.7 1.8 0.9 2.2 0.9 2.7 1.0 0.8 2.3 1.8 2.3 2.4 0.6 7.9 0.0 3.7 3.9 0.8 5.5 4.3 4.4 8.5 1.9 0.7 0.0 2.1 8.2 0.1 0.9 0.0 0.1 7.2 0.0 0.9 0.6 2.5 0.0 2.2 0.0 3.0 2.4 0.4 9.6 0.0 0.0 7.8 0.0 0.0 0.7 2.0 0.0 0.3 0.3 5.8 0.8 0.0 0.4 6.5 0.0 1.1 1.4 5.3 4.9 0.8 0.0 3.0 1.3 0.6 1.2 2.9 2.0 1.2 6.1 0.0 0.0 0.0 0.0 3.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.1 1.4 2.0 2.0 3.0 1.8 2.1 2.1 1.1 2.2 2.3 8.7 3.2 6.8 66.6 2.2 2.4 7.7 1.7 5.7 24.5 9.1 7.1 10.5 2.8 7.9 27.6 8.4 1.7 2.6 2.3 17.6 2.7 0.2 5.6 8.9 8.0 3.0 1.3 59.1 2.3 0.7 11.0 2.0 8.3 3.8 13.3 5.3 2.5 2.3 23.5 87.5 2.3 6.1 3.8 5.1 0.7 10.5 2.4 17.8 63.7 2.8 11.6 4.1 78.4 75.6 2.0 3.9 12.4 2.2 5.3 4.7 4.8 9.8 7.8 0.0 8.1 10.9 1.3 1.3 1.8 3.4 1.5 2.2 8.4 4.0 4.5 ARNTL "bHLHe5, BMAL1, JAP3, MOP3, PASD3" ENSG00000133794 "Aryl hydrocarbon receptor nuclear translocator like" O00327 11 13276652-13387266 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 63.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 11.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045962, HPA050938" Supported Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "CAB045962: AB_11124144, HPA050938: AB_2681282" "unprognostic (1.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.95e-2)" "unprognostic (1.63e-1)" "unprognostic (9.00e-2)" "unprognostic (1.77e-1)" "unprognostic (3.72e-1)" "unprognostic (3.76e-2)" "unprognostic (8.92e-2)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "unprognostic (7.80e-2)" "unprognostic (1.34e-2)" "unprognostic (2.10e-1)" "unprognostic (2.77e-2)" "unprognostic (3.11e-2)" "unprognostic (7.08e-2)" 15.0 13.3 3.2 5.1 4.8 7.4 14.1 4.8 8.3 10.5 3.2 12.4 5.2 11.6 1.6 10.5 11.5 4.0 9.5 5.5 1.9 7.2 19.4 15.0 5.8 1.6 2.6 19.7 10.3 1.5 12.3 4.4 2.2 8.5 4.1 23.4 12.7 3.4 27.0 17.6 12.4 5.6 1.9 11.6 10.9 10.9 4.4 14.1 18.9 8.2 6.4 9.3 11.5 7.4 8.2 9.0 7.5 4.0 15.0 9.0 5.7 9.5 8.1 8.6 9.7 3.7 10.9 0.1 2.6 5.2 10.4 3.4 5.3 10.3 7.7 13.6 6.3 3.9 6.6 1.8 23.7 1.8 16.2 10.1 21.3 3.7 14.1 5.9 6.2 12.6 2.5 14.9 6.9 4.7 4.7 0.9 1.6 5.4 4.3 5.1 11.4 3.4 5.7 1.8 1.2 12.2 6.1 0.7 7.6 7.1 5.7 7.0 11.5 6.2 6.8 20.3 5.5 4.1 12.0 0.0 6.4 4.1 8.3 4.3 8.3 17.9 18.1 9.0 25.2 2.6 16.8 15.6 8.4 3.1 9.4 11.1 24.5 14.1 8.9 1.1 11.1 10.7 3.2 4.8 4.8 8.3 5.5 1.9 1.6 2.6 2.2 1.9 4.4 7.4 4.9 25.6 21.0 49.9 9.0 30.8 13.4 7.3 10.2 28.3 6.1 5.0 8.8 10.0 11.1 1.8 16.7 17.6 34.8 8.6 17.6 6.8 1.5 6.1 14.2 6.6 1.2 3.0 63.6 6.4 2.2 10.3 11.7 12.9 2.5 6.9 10.8 22.9 8.2 30.3 30.5 4.6 4.1 14.0 12.3 4.2 12.8 11.9 3.6 18.7 13.1 18.8 32.0 34.2 11.9 8.3 9.3 19.9 11.5 8.0 13.5 11.3 5.3 30.9 13.1 6.6 10.7 4.7 5.4 9.4 32.4 6.3 33.0 4.7 4.5 12.0 ARSA ENSG00000100299 "Arylsulfatase A" P15289 22 50622754-50628173 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 127.5;Plasma cells: 132.0;Proximal enterocytes: 93.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 80.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005554, CAB025183" Enhanced Uncertain "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 5600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" Cytosol "CAB025183: , HPA005554: AB_1078220" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (4.07e-2)" "prognostic favorable (2.96e-5)" "unprognostic (4.66e-2)" "unprognostic (4.40e-1)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.61e-2)" "unprognostic (2.16e-1)" "unprognostic (4.47e-2)" "unprognostic (2.76e-1)" "unprognostic (9.90e-2)" "unprognostic (1.41e-2)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (7.73e-3)" 28.8 25.1 14.4 15.6 18.0 18.4 27.2 16.8 21.8 21.3 27.5 31.3 30.8 22.4 8.6 28.1 25.1 15.7 33.0 14.9 15.2 31.4 42.8 29.1 19.8 20.0 15.9 11.3 46.7 11.7 34.7 10.9 19.1 28.9 8.2 4.4 39.6 16.2 25.3 17.5 33.8 6.5 16.3 44.5 30.3 54.0 19.4 9.8 32.3 5.1 9.5 23.9 24.7 21.0 8.5 11.0 5.3 10.9 41.8 21.8 13.5 13.0 15.9 5.7 9.3 3.3 12.9 5.3 8.2 22.9 10.8 12.8 1.2 12.3 1.0 2.7 8.0 3.4 14.3 12.5 28.3 5.2 32.7 26.0 24.4 9.5 6.3 19.9 12.8 11.5 3.5 80.4 12.1 9.6 4.6 5.8 1.7 9.0 11.2 4.0 0.4 26.7 9.9 13.5 2.5 8.2 18.2 17.2 10.1 5.1 7.7 6.6 22.1 3.8 15.1 14.9 4.1 18.4 1.9 4.5 11.7 4.3 13.6 10.4 27.7 36.1 17.3 33.3 15.1 10.4 12.4 14.2 22.7 12.5 7.3 10.0 60.4 8.9 43.2 32.1 18.2 16.3 14.4 18.0 16.8 21.8 14.9 15.2 20.0 15.9 19.1 16.3 19.4 21.0 22.8 6.4 12.9 24.5 22.2 4.7 14.0 23.8 18.8 5.3 18.9 13.1 8.0 27.1 15.5 12.9 4.2 11.5 14.0 85.4 1.9 29.4 62.4 24.4 10.3 13.4 36.7 9.7 9.4 21.3 19.9 19.6 41.3 21.3 6.3 15.3 8.2 28.6 36.8 6.7 8.6 30.6 14.2 29.0 9.5 127.5 10.8 29.2 17.8 10.3 28.7 10.3 8.2 8.0 11.9 24.2 75.2 6.0 132.0 10.8 93.9 22.7 21.2 7.2 0.0 6.6 9.9 48.3 4.1 18.3 5.5 13.3 17.2 7.2 25.0 16.1 ARSB ENSG00000113273 "Arylsulfatase B" P15848 5 78777209-78986087 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 40.8;Excitatory neurons: 37.4;Inhibitory neurons: 42.5;Microglial cells: 40.3;Oligodendrocyte precursor cells: 71.4;Oligodendrocytes: 56.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 25.6" "Group enriched" "Detected in many" 7 "dendritic cells: 7.8;granulocytes: 25.6;monocytes: 8.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037770, HPA037771" Approved Approved "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus" "HPA037770: AB_10671719, HPA037771: AB_10671720" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.97e-2)" "unprognostic (1.09e-2)" "unprognostic (7.34e-2)" "unprognostic (2.65e-1)" "unprognostic (8.69e-3)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (7.20e-2)" "unprognostic (1.74e-1)" "unprognostic (3.59e-2)" "unprognostic (2.48e-2)" "unprognostic (9.57e-3)" "unprognostic (9.88e-2)" "unprognostic (6.54e-3)" "prognostic unfavorable (3.42e-4)" 6.9 4.5 3.9 8.1 3.9 8.1 2.6 3.1 4.6 5.3 4.2 5.5 3.1 6.4 3.5 4.8 2.9 7.3 8.3 4.7 3.6 21.3 7.6 7.0 5.4 4.6 5.3 2.2 4.6 6.6 2.5 11.5 4.0 5.0 8.2 6.7 3.1 6.6 3.8 2.1 3.6 14.1 4.3 5.2 3.9 2.6 5.2 2.6 4.2 4.3 4.8 8.0 2.3 5.0 5.0 11.3 18.6 6.3 41.9 16.4 16.7 29.2 23.0 18.9 23.0 9.9 8.4 6.5 31.5 25.5 29.0 3.9 7.0 7.4 18.5 55.6 6.2 9.2 11.2 40.1 9.7 10.5 10.4 19.4 2.4 19.7 6.5 15.6 22.4 3.9 2.0 12.9 19.6 9.2 5.8 19.3 5.6 1.1 6.7 7.7 10.9 5.9 12.0 6.2 6.8 15.9 20.3 6.2 12.1 12.7 6.9 26.2 16.2 17.5 10.4 7.6 26.4 14.8 28.0 7.2 21.6 21.4 40.3 19.0 8.3 25.6 1.0 6.7 0.6 2.0 0.4 0.4 7.8 1.3 0.3 0.5 4.6 0.2 5.6 5.7 0.7 2.7 3.9 3.9 3.1 4.6 4.7 3.6 4.6 5.3 4.0 4.3 5.2 5.0 3.9 0.0 2.0 40.8 5.1 0.8 1.4 1.3 0.6 3.7 1.6 1.0 7.2 1.5 0.7 3.7 6.2 2.2 5.5 1.4 3.9 3.7 0.5 1.9 7.2 4.5 1.2 16.2 37.4 9.2 5.1 6.6 2.6 9.0 0.0 6.3 13.6 3.8 16.7 6.7 42.5 6.0 0.0 25.2 14.3 0.5 4.4 15.9 14.2 40.3 16.1 3.6 2.1 71.4 56.2 4.0 3.0 3.8 8.1 2.2 0.5 18.8 2.5 2.7 6.6 5.0 4.4 2.2 3.1 0.7 1.3 2.6 3.4 1.6 2.2 1.3 ARSG KIAA1001 ENSG00000141337 "Arylsulfatase G" Q96EG1 17 68259182-68422731 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 30.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.2;NK-cells: 42.2;Rod photoreceptor cells: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023245, HPA023285" Enhanced "Intracellular and membrane" NA NA 4400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA023245: AB_1845056, HPA023285: AB_1845057" "unprognostic (3.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" "unprognostic (1.61e-1)" "unprognostic (9.02e-2)" "unprognostic (3.67e-3)" "unprognostic (4.11e-1)" "unprognostic (1.14e-3)" "unprognostic (5.18e-2)" "unprognostic (5.47e-2)" "unprognostic (6.11e-7)" "unprognostic (4.24e-3)" "prognostic favorable (7.04e-4)" "unprognostic (1.87e-2)" "unprognostic (3.68e-2)" "unprognostic (3.18e-2)" "unprognostic (1.49e-1)" 2.6 4.6 1.5 2.9 2.0 3.4 5.5 6.6 2.0 3.5 8.6 2.2 1.1 3.8 30.2 4.4 6.6 2.1 4.9 1.1 2.9 3.0 2.5 2.4 3.9 2.5 3.6 6.2 2.3 1.2 5.3 2.6 3.6 2.0 1.1 7.8 3.3 5.5 3.7 4.5 1.9 2.1 0.7 4.9 2.6 2.1 2.1 2.5 7.5 3.0 3.6 2.0 2.0 1.4 1.4 1.7 1.3 2.1 7.0 4.3 5.7 1.9 5.7 2.7 1.3 0.7 3.2 3.3 4.8 2.5 1.1 0.2 2.2 0.7 1.0 4.8 2.0 1.8 1.8 5.4 5.7 5.1 3.6 1.6 1.3 0.7 2.8 7.2 3.1 5.0 1.0 9.5 1.2 6.2 5.9 4.1 2.0 0.6 1.6 0.2 1.0 8.8 4.1 0.9 7.0 0.6 2.3 5.5 12.1 2.7 13.5 6.1 3.3 4.2 0.4 1.6 0.7 10.5 5.8 5.0 3.3 6.4 1.6 7.1 8.5 6.5 6.3 6.1 4.4 4.0 4.2 6.0 7.7 2.2 4.2 6.0 12.8 4.3 5.2 1.2 4.7 5.4 1.5 2.0 6.6 2.0 1.1 2.9 2.5 3.6 3.6 0.7 2.1 1.4 4.9 3.2 2.7 11.8 7.7 4.0 5.0 4.7 0.0 23.8 9.2 3.8 2.7 8.6 4.8 12.9 54.2 8.1 11.2 3.6 9.8 3.2 0.4 8.7 9.2 8.6 1.8 5.3 18.8 4.7 23.8 24.3 2.6 11.7 3.8 6.4 17.5 3.0 9.2 26.9 26.0 5.2 0.0 6.9 10.7 1.3 13.4 8.4 23.2 12.2 16.0 9.4 42.2 7.1 2.7 2.3 10.9 23.0 11.1 10.0 2.4 12.8 4.3 59.6 6.6 8.7 5.5 1.4 3.6 6.0 3.8 16.8 13.6 9.3 2.3 8.8 ARSI "FLJ16069, SPG66" ENSG00000183876 "Arylsulfatase family member I" Q5FYB1 5 150296343-150339307 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.1;Fibroblasts: 10.8;Melanocytes: 21.4;Smooth muscle cells: 6.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 15.7;HaCaT: 31.4;Hep G2: 19.9;hTEC/SVTERT24-B: 30.9;U-87 MG: 39.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA038386, HPA038398" Uncertain Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA038386: AB_10669781, HPA038398: AB_2675995" "unprognostic (6.08e-2)" "unprognostic (1.70e-2)" "unprognostic (9.41e-3)" "unprognostic (4.77e-3)" "unprognostic (1.54e-3)" "unprognostic (2.83e-3)" "unprognostic (2.76e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.06e-1)" "unprognostic (5.81e-3)" "unprognostic (4.85e-2)" "unprognostic (1.26e-1)" "unprognostic (3.39e-7)" "unprognostic (7.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.19e-4)" 1.2 0.3 1.6 2.3 2.6 0.6 0.4 2.5 2.1 2.7 0.7 1.6 0.6 3.1 0.6 1.8 2.1 1.1 1.3 1.4 1.8 0.7 0.4 4.5 0.3 3.6 2.4 0.4 0.4 0.6 1.0 2.8 3.9 1.7 0.4 0.4 0.5 0.8 0.8 4.8 0.7 2.8 2.6 0.8 0.8 0.4 2.8 0.3 0.2 0.5 0.4 3.8 2.7 5.5 1.0 3.8 1.1 0.0 0.0 0.8 0.0 8.1 12.1 15.7 11.5 1.1 1.8 0.0 3.1 11.5 1.3 31.4 0.2 5.3 5.6 0.0 0.1 0.0 0.4 19.9 1.5 0.0 0.0 0.8 3.4 30.9 0.9 10.7 0.2 0.0 0.0 0.2 2.5 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.1 0.4 0.0 0.2 0.0 6.7 0.9 1.3 11.2 0.0 0.0 0.0 0.3 10.2 0.3 0.0 0.0 0.0 0.0 39.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.6 2.5 2.1 1.4 1.8 3.6 2.4 3.9 2.6 2.8 5.5 0.1 0.0 0.0 0.3 0.0 12.1 0.0 2.4 0.0 0.1 0.1 0.4 1.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.0 0.0 0.1 0.0 1.1 10.8 0.0 0.0 4.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.1 0.0 0.8 0.2 0.6 0.0 21.4 0.0 0.0 3.9 0.0 0.0 2.5 0.4 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.3 0.0 1.8 6.6 0.1 0.9 0.9 4.7 1.4 1.1 0.0 0.0 0.0 ARSJ FLJ23548 ENSG00000180801 "Arylsulfatase family member J" Q5FYB0 4 113900284-113979727 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 35.3;Astrocytes: 44.1;Basal prostatic cells: 60.3;Prostatic glandular cells: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 46.4;HUVEC TERT2: 42.2;LHCN-M2: 42.8;TIME: 53.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036481, HPA036482" Uncertain Enhanced "Actin filaments" "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "HPA036481: AB_2675146, HPA036482: AB_10672356" "unprognostic (1.98e-1)" "unprognostic (1.55e-2)" "unprognostic (4.23e-1)" "unprognostic (5.31e-1)" "unprognostic (6.23e-2)" "prognostic unfavorable (6.08e-4)" "unprognostic (2.54e-2)" "unprognostic (2.49e-2)" "unprognostic (1.60e-1)" "unprognostic (1.04e-1)" "unprognostic (5.31e-2)" "unprognostic (2.20e-1)" "prognostic favorable (2.97e-6)" "unprognostic (2.26e-1)" "unprognostic (8.37e-2)" "unprognostic (1.30e-1)" "unprognostic (2.07e-2)" 1.8 1.3 1.5 1.3 1.1 0.0 1.0 5.0 1.4 4.5 0.2 2.4 0.6 2.0 0.9 3.1 2.8 3.6 2.5 1.2 0.9 2.7 1.7 3.3 0.6 0.9 1.1 2.0 1.1 3.0 0.7 4.3 0.7 3.9 3.3 0.6 5.8 2.2 0.2 0.7 0.7 2.2 0.6 0.2 3.5 0.1 1.9 1.5 0.7 0.6 0.3 3.8 2.1 1.1 2.7 5.3 0.6 0.0 10.1 20.5 0.0 46.4 35.5 29.0 11.3 1.3 3.4 0.0 5.7 22.6 10.3 5.0 0.2 11.7 36.2 0.0 2.1 0.0 4.2 0.0 30.6 0.0 0.0 12.7 11.5 19.7 40.0 20.5 42.2 0.0 0.0 0.0 42.8 0.4 0.0 0.0 1.5 0.0 8.4 0.0 5.1 0.0 38.0 0.0 0.0 1.7 3.1 0.5 2.2 7.5 0.2 0.0 53.6 33.3 8.7 5.0 22.3 0.0 0.0 0.0 16.2 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 5.0 1.4 1.2 0.9 0.9 1.1 0.7 0.6 1.9 1.1 0.7 35.3 9.8 44.1 0.2 2.9 60.3 23.7 15.9 0.2 4.7 2.9 1.3 11.5 10.8 25.8 0.0 0.3 0.1 7.0 0.0 9.2 0.0 6.2 21.1 4.3 23.4 0.0 27.1 0.9 0.2 13.6 4.6 8.2 0.0 0.0 4.2 1.2 0.5 1.7 1.5 17.3 16.2 0.3 1.6 0.3 2.5 0.3 3.6 7.5 0.0 6.8 1.0 3.0 0.5 5.2 5.0 1.5 0.0 49.6 0.1 4.1 4.6 0.2 0.0 8.6 10.5 0.1 0.3 16.9 1.1 0.4 0.6 3.3 4.1 25.6 ARSK "DKFZp313G1735, TSULF" ENSG00000164291 "Arylsulfatase family member K" Q6UWY0 5 95555101-95605102 "Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 19.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042384 Approved Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles Nucleoplasm "HPA042384: AB_10795703" "unprognostic (9.50e-2)" "unprognostic (1.37e-1)" "unprognostic (2.03e-3)" "unprognostic (2.39e-1)" "unprognostic (3.33e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (2.59e-4)" "unprognostic (3.39e-1)" "unprognostic (1.37e-1)" "unprognostic (5.19e-2)" "unprognostic (7.61e-2)" "unprognostic (2.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.91e-2)" "unprognostic (2.32e-1)" "unprognostic (8.20e-2)" "unprognostic (1.06e-2)" 3.0 3.7 2.1 2.2 2.3 2.3 3.3 2.8 3.0 3.8 2.1 2.7 2.2 3.6 4.2 2.9 3.2 3.1 2.6 2.4 2.1 5.4 3.7 2.9 2.7 1.9 1.9 5.8 4.9 19.1 2.6 5.5 2.3 4.9 2.5 3.6 2.8 4.9 2.3 3.3 2.2 3.0 1.7 2.4 4.2 1.6 2.6 3.7 5.0 2.7 2.0 3.2 3.3 2.2 5.1 3.2 6.6 6.6 32.4 16.8 9.5 15.9 9.2 6.1 12.4 3.9 7.8 6.9 8.1 5.5 10.9 4.6 5.8 10.1 13.3 7.4 8.5 5.5 7.7 6.7 9.4 3.1 4.4 12.4 8.9 9.2 5.9 12.8 10.0 9.3 5.6 7.4 13.7 2.5 8.5 5.9 8.6 1.6 15.3 5.2 10.6 11.0 14.1 1.2 4.7 4.8 9.7 3.1 10.0 9.1 8.9 3.2 18.1 9.6 7.8 15.0 9.9 6.2 11.2 8.4 9.6 8.0 36.5 12.9 1.1 2.1 4.0 1.2 4.7 4.9 4.7 5.4 0.6 5.0 7.0 5.2 0.9 3.3 0.7 2.2 3.9 1.8 2.1 2.3 2.8 3.0 2.4 2.1 1.9 1.9 2.3 1.7 2.6 2.2 6.8 3.2 2.2 9.1 6.6 4.5 6.8 7.4 5.7 7.3 4.4 7.2 4.6 1.5 3.7 7.3 12.5 11.8 6.6 1.9 3.9 4.1 9.2 7.1 10.3 6.2 3.0 10.1 11.0 2.5 47.4 13.6 2.0 5.7 22.9 8.1 6.8 16.5 4.6 10.1 9.7 2.0 10.2 3.2 5.4 2.9 10.8 4.9 5.4 7.5 5.1 12.7 14.4 7.1 10.0 2.6 3.2 11.7 7.1 3.9 3.2 4.8 6.8 10.4 0.0 10.2 10.9 7.4 8.6 5.1 7.0 5.1 9.8 11.8 3.4 2.1 ARSL "ARSE, CDPX, CDPX1" ENSG00000157399 "Arylsulfatase L" P51690 X 2934521-2968475 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 36.6;liver: 86.3;pancreas: 105.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 34.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 68.9;CACO-2: 42.7;GAMG: 30.8;Hep G2: 64.1;NTERA-2: 33.6" "Low region specificity" "Detected in all" "HPA060518, HPA070651" Approved Supported "Golgi apparatus" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA060518: AB_2684301, HPA070651: AB_2732160" "unprognostic (2.07e-1)" "unprognostic (6.60e-3)" "prognostic favorable (8.95e-4)" "unprognostic (8.74e-3)" "unprognostic (1.14e-3)" "unprognostic (3.48e-2)" "unprognostic (2.38e-1)" "unprognostic (8.27e-2)" "unprognostic (5.45e-2)" "unprognostic (2.25e-1)" "unprognostic (2.27e-1)" "unprognostic (2.37e-1)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (1.28e-1)" "unprognostic (5.94e-2)" "unprognostic (4.76e-2)" 0.4 0.7 2.6 2.2 2.7 0.3 1.1 2.1 2.8 1.7 4.5 20.8 17.9 3.2 2.2 0.4 4.1 8.2 1.0 2.8 2.6 36.6 86.3 2.7 0.1 2.8 2.8 7.1 105.2 0.0 0.7 0.7 2.9 0.5 16.7 0.3 1.3 2.9 0.2 0.2 13.6 1.9 2.4 0.0 2.9 0.4 2.6 0.0 0.2 0.3 0.1 0.5 1.6 2.3 4.5 68.9 8.2 0.0 3.3 4.0 1.3 3.9 6.4 4.0 4.0 42.7 0.0 0.0 13.7 0.1 30.8 0.0 0.0 0.9 2.3 0.0 4.5 0.0 0.0 64.1 1.8 0.0 0.1 9.6 0.0 3.8 0.0 7.3 3.8 0.0 0.0 0.1 10.5 0.1 0.0 0.0 33.6 2.4 0.2 2.8 1.1 0.3 7.1 0.0 0.1 0.2 0.0 0.0 2.6 13.7 0.0 0.2 5.0 0.1 0.2 0.0 7.4 0.0 0.0 0.1 9.1 0.1 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.7 2.1 2.8 2.8 2.6 2.8 2.8 2.9 2.4 2.6 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ART3 ARTC3 ENSG00000156219 "ADP-ribosyltransferase 3 (inactive)" Q13508 4 76011184-76112802 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "heart muscle: 67.3;skeletal muscle: 220.2;testis: 96.4;tongue: 101.6" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 76.2;Spermatocytes: 262.8" "Cancer enhanced" "Detected in some" "breast cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "NB-4: 5.5;NTERA-2: 14.1;SK-MEL-30: 6.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA011268 Enhanced "Intracellular and membrane" NA NA 48000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA011268: AB_1845059" "unprognostic (2.45e-1)" "unprognostic (2.84e-2)" "unprognostic (3.12e-2)" "unprognostic (2.77e-3)" "unprognostic (4.53e-2)" "unprognostic (1.34e-1)" "unprognostic (3.34e-1)" "unprognostic (9.85e-4)" "unprognostic (2.35e-1)" "unprognostic (5.10e-2)" "unprognostic (1.64e-2)" "unprognostic (2.95e-1)" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.48e-1)" "unprognostic (2.58e-2)" "unprognostic (6.61e-3)" 1.0 0.4 3.4 1.1 4.2 0.0 0.9 6.9 9.4 2.2 4.0 3.7 0.3 0.3 0.5 4.7 0.9 0.2 67.3 4.7 4.6 0.2 0.2 0.4 0.3 3.3 3.3 0.4 7.9 0.1 2.5 0.1 2.8 2.0 2.2 0.2 3.1 1.3 220.2 0.9 2.3 0.4 3.5 2.7 1.9 96.4 2.7 0.6 0.3 101.6 0.1 0.7 1.7 9.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.5 14.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 4.2 6.9 9.4 4.7 4.6 3.3 3.3 2.8 3.5 2.7 9.9 0.4 0.0 0.0 0.7 0.1 0.5 0.5 1.1 0.0 0.5 0.2 0.3 76.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.3 2.1 0.4 0.8 0.0 0.0 37.9 0.0 0.1 2.6 0.0 5.9 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.4 13.5 1.8 0.2 1.8 0.0 0.0 0.3 0.0 5.0 7.3 0.0 0.0 1.2 0.0 1.0 0.0 0.0 0.1 0.3 0.0 21.7 2.7 262.8 24.2 0.0 0.3 0.0 0.2 0.1 0.8 0.4 ART4 "ARTC4, CD297, DO, DOK1" ENSG00000111339 "ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)" Q93070 12 14825569-14843526 "Blood group antigen proteins, CD markers, Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 53.3;lymphoid tissue: 19.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 15.7;Endothelial cells: 12.9;Erythroid cells: 51.3;Hepatic stellate cells: 66.0;Hepatocytes: 30.2" "Group enriched" "Detected in some" 5 "liver cancer: 3.8;pancreatic cancer: 1.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.0;HEL: 12.1;Hep G2: 7.3;HUVEC TERT2: 27.0" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Low region specificity" "Detected in all" HPA075664 Approved "Rods & Rings" "Secreted to blood" NA NA 17000000 "Cluster 85: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" "Rods & Rings" "HPA075664: " "unprognostic (2.50e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-1)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.90e-2)" "unprognostic (2.62e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-3)" "unprognostic (1.05e-1)" "unprognostic (1.71e-1)" 2.6 2.7 0.3 1.1 0.5 4.6 1.8 0.1 0.4 0.9 0.4 0.6 0.0 0.8 0.3 0.9 2.1 9.0 9.0 0.3 1.1 3.6 53.3 3.2 8.6 0.5 0.4 0.5 2.3 0.3 0.1 7.0 0.4 0.3 0.5 0.3 0.7 0.4 0.3 0.3 0.6 1.1 0.2 19.0 0.3 0.2 0.4 1.9 3.6 0.2 2.3 0.6 0.5 0.6 0.0 0.0 0.2 6.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 7.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.1 0.4 0.3 1.1 0.5 0.4 0.4 0.2 0.4 0.6 0.7 0.0 1.1 0.7 0.2 0.3 0.8 0.0 0.0 2.4 0.2 0.1 1.5 15.7 0.0 1.8 12.5 0.9 0.1 0.0 0.0 0.9 0.4 0.2 0.1 12.9 0.0 51.3 0.2 1.9 2.5 1.9 0.0 0.1 0.0 0.0 66.0 30.2 0.1 0.0 0.2 0.0 0.0 4.7 1.3 0.3 1.8 0.1 1.8 0.0 0.0 0.3 1.0 0.0 0.3 0.6 0.0 0.0 0.0 0.2 0.0 0.2 0.0 11.8 6.6 0.5 1.2 0.1 0.1 0.0 0.1 0.3 0.2 0.0 0.0 0.4 ART5 ARTC5 ENSG00000167311 "ADP-ribosyltransferase 5" Q96L15 11 3638512-3642316 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 13.4;testis: 29.4" "Group enriched" "Detected in some" 8 "Early spermatids: 18.3;Late spermatids: 18.5;Spermatocytes: 64.9" "Cancer enriched" "Detected in some" 4 "testis cancer: 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 13.9" "Not detected" "Not detected" "HPA041637, HPA044099" Uncertain "Secreted in other tissues" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA041637: AB_2677589, HPA044099: AB_2678808" "unprognostic (6.32e-2)" "unprognostic (3.26e-5)" "unprognostic (4.09e-3)" "unprognostic (2.06e-4)" "unprognostic (1.53e-2)" "unprognostic (1.47e-2)" "unprognostic (2.22e-2)" "unprognostic (1.21e-2)" "unprognostic (5.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.17e-1)" "unprognostic (1.67e-1)" "prognostic favorable (1.85e-4)" "unprognostic (3.10e-3)" "unprognostic (3.46e-2)" "unprognostic (1.96e-1)" "unprognostic (3.18e-1)" 0.7 0.2 0.3 0.0 0.3 0.0 1.0 0.3 0.5 4.1 0.6 0.3 0.0 3.6 0.7 0.5 1.5 1.4 1.8 0.3 0.8 0.8 0.9 0.9 0.1 0.4 0.4 8.3 0.4 2.9 0.7 0.1 0.6 1.1 0.0 0.6 1.6 0.9 13.4 0.5 0.2 1.1 0.3 0.0 0.5 29.4 0.4 0.3 2.8 10.5 0.0 0.7 2.2 0.3 0.0 0.1 1.6 2.0 0.0 0.0 3.2 0.2 1.6 0.7 1.8 0.0 0.0 0.0 0.8 0.2 0.0 0.0 1.5 0.0 0.4 0.0 2.2 0.0 0.3 0.1 0.0 0.0 1.4 0.5 0.0 0.0 0.0 0.2 0.0 0.1 0.6 0.0 0.2 0.3 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.5 0.0 13.9 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.3 0.8 0.4 0.4 0.6 0.3 0.4 0.3 0.1 0.0 1.8 0.0 0.0 0.3 2.2 0.0 2.8 0.8 0.3 1.3 2.5 0.0 0.6 0.0 0.0 0.6 0.0 0.1 0.0 0.6 18.3 0.1 0.2 0.4 0.0 0.0 0.0 0.2 0.5 1.3 0.0 0.2 0.0 3.3 0.0 1.8 0.1 0.0 0.0 0.2 0.0 0.3 0.0 18.5 3.4 0.1 0.0 1.0 0.0 3.6 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.8 0.0 0.6 0.0 0.9 0.0 1.3 0.2 64.9 3.9 0.1 0.3 2.9 0.0 1.2 0.0 0.3 ARTN "ENOVIN, EVN, NBN" ENSG00000117407 Artemin Q5T4W7 1 43933320-43937240 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Urothelial cells: 51.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "A-431: 61.9;HaCaT: 62.8;HBEC3-KT: 57.0;hTCEpi: 22.7;hTERT-HME1: 15.9" "Region enriched" "Detected in single" 9 "olfactory bulb: 3.3" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (1.98e-1)" "unprognostic (1.25e-1)" "unprognostic (3.60e-2)" "unprognostic (1.86e-1)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (3.07e-3)" "unprognostic (1.18e-1)" "unprognostic (3.08e-1)" "prognostic favorable (8.18e-4)" "unprognostic (2.34e-1)" "unprognostic (1.70e-1)" "unprognostic (9.59e-6)" "unprognostic (2.35e-2)" "unprognostic (3.04e-2)" "unprognostic (1.48e-3)" "unprognostic (1.53e-1)" 2.8 0.9 1.5 0.9 1.1 0.8 1.8 2.9 2.3 4.5 1.2 2.4 0.4 3.2 3.4 3.8 2.8 0.9 2.0 1.2 1.0 4.1 0.7 2.3 0.3 4.4 2.2 2.1 2.8 6.7 6.6 7.4 4.5 8.3 1.6 1.7 1.5 8.1 0.7 1.0 1.2 1.3 1.0 0.7 1.7 2.4 5.4 0.3 1.4 0.3 0.3 2.3 4.7 1.0 61.9 1.5 1.2 0.9 0.2 0.3 0.2 2.8 0.5 2.3 2.5 0.4 1.4 0.8 0.4 0.9 0.8 62.8 0.0 57.0 0.6 0.2 2.1 1.0 7.6 0.1 0.0 0.4 1.3 0.0 22.7 1.1 15.9 10.6 0.0 1.1 0.7 2.1 0.2 4.3 0.2 4.0 5.4 0.0 2.6 1.4 0.0 0.9 0.3 1.3 1.4 0.5 0.4 0.1 1.4 1.1 10.2 10.4 0.6 1.2 0.5 0.5 2.8 6.7 5.5 0.9 8.8 3.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 2.9 2.3 1.2 1.0 4.4 2.2 4.5 1.0 5.4 1.0 0.1 0.0 0.0 0.0 0.1 0.0 4.3 2.3 0.0 1.8 2.3 0.5 0.8 0.0 2.8 0.0 0.0 0.1 0.3 2.8 3.9 0.1 8.4 1.6 0.3 0.2 0.0 0.0 0.7 0.2 0.0 0.3 0.0 1.9 0.0 3.2 0.0 0.0 0.1 0.0 1.2 1.0 0.0 0.0 0.5 2.6 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 1.1 0.4 0.0 12.1 0.0 1.6 0.7 4.6 0.0 0.0 4.0 4.3 0.0 0.0 0.0 0.0 0.1 0.8 0.7 51.5 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 573.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 777.0;Hofbauer cells: 921.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 392.8;SK-MEL-30: 590.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 214.3 71.9 50.1 51.6 51.5 107.7 95.8 62.1 50.8 98.5 62.6 84.3 54.7 55.8 131.5 73.2 70.4 99.1 573.9 49.9 66.2 204.0 60.9 190.3 65.9 66.0 59.4 50.1 49.6 117.8 83.6 121.5 69.0 84.3 87.0 79.5 66.6 77.9 66.0 52.6 56.8 61.7 66.3 85.4 61.2 18.2 59.1 26.0 325.5 70.7 57.7 112.8 54.8 102.2 48.1 66.4 25.9 63.3 392.8 46.0 39.2 48.2 67.3 23.0 41.0 35.4 66.1 30.2 60.3 54.5 159.1 62.6 15.0 25.3 28.4 22.9 38.9 134.4 46.7 96.7 107.5 27.7 140.7 100.2 86.5 33.6 22.9 53.2 6.2 50.6 24.3 61.7 67.9 46.0 15.5 48.3 30.3 105.2 40.5 19.4 25.5 41.4 112.0 273.0 40.4 55.0 43.8 145.2 590.5 35.6 47.9 31.3 43.6 30.3 43.1 55.8 23.7 75.5 184.3 22.0 89.5 61.3 24.6 285.2 455.4 318.7 47.6 676.4 43.1 83.9 35.5 36.1 175.1 65.9 40.8 37.9 627.6 60.5 731.4 33.0 43.7 407.2 50.1 51.5 62.1 50.8 49.9 66.2 66.0 59.4 69.0 66.3 59.1 102.2 98.5 317.3 405.0 36.9 92.8 58.6 83.3 103.7 35.3 97.5 105.6 87.8 777.0 100.1 280.9 450.6 45.9 177.4 67.6 83.4 60.7 150.6 2.8 85.7 51.5 79.7 98.1 106.3 49.8 104.1 65.2 122.0 43.3 133.8 257.0 49.3 134.6 50.6 921.2 77.4 53.2 99.3 201.4 564.3 89.9 6.0 88.6 524.6 318.4 56.2 259.2 532.6 53.5 49.8 49.0 64.7 125.5 105.7 87.4 87.8 77.6 304.2 147.3 88.0 177.5 74.5 157.0 14.0 63.6 84.9 64.2 148.2 61.3 53.4 89.7 139.9 ASAH2 ENSG00000188611 "N-acylsphingosine amidohydrolase 2" Q9NR71 10 50182778-50279720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 81.5" "Cell type enhanced" "Detected in some" "Late spermatids: 12.5;Muller glia cells: 9.0;Proximal enterocytes: 17.1;Sertoli cells: 6.6" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "cerebellum: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061171 Supported Approved "Focal adhesion sites" "Intracellular and membrane" NA NA 2200000 "Cluster 32: T-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 45: Enterocytes - Digestion" "Focal adhesion sites" "HPA061171: AB_2684442" "unprognostic (3.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.66e-1)" "unprognostic (3.84e-2)" "unprognostic (3.66e-1)" "unprognostic (4.48e-2)" "unprognostic (2.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-2)" "unprognostic (4.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.86e-2)" "unprognostic (5.64e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" 0.4 0.8 0.0 0.2 1.1 0.0 0.5 8.1 0.4 0.7 0.1 0.8 81.5 0.8 0.5 0.7 0.8 0.3 0.8 0.1 0.4 0.5 2.9 0.6 0.3 3.2 2.9 0.8 1.4 0.6 0.6 0.6 2.2 0.4 0.4 7.3 0.6 0.2 0.8 0.7 64.6 1.2 1.5 0.2 5.0 0.8 0.6 0.5 0.7 0.4 0.1 0.5 0.4 0.6 1.2 0.9 1.0 1.4 1.8 0.7 1.3 1.2 0.9 2.5 2.2 0.7 3.0 0.0 1.4 1.9 2.0 1.1 1.4 0.4 3.0 1.6 2.5 0.9 2.2 1.9 1.1 0.3 0.1 0.2 1.7 4.3 4.8 0.3 0.5 0.0 1.7 0.8 1.7 1.1 1.0 0.0 3.2 0.0 2.7 0.0 4.2 1.1 1.3 0.2 1.8 4.8 1.7 1.2 2.1 2.4 1.0 0.7 1.4 1.2 2.8 3.2 4.0 1.2 0.1 0.0 3.5 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.1 8.1 0.4 0.1 0.4 3.2 2.9 2.2 1.5 0.6 0.6 0.1 0.0 0.0 0.7 0.0 0.4 0.3 0.4 0.0 2.8 0.4 0.3 3.8 0.0 0.9 0.0 2.1 0.4 1.4 0.5 0.0 0.9 4.8 0.1 0.2 0.5 0.0 3.2 1.1 1.6 0.3 0.6 0.0 0.2 0.0 0.2 0.4 2.1 0.2 1.7 1.5 1.8 0.0 0.0 0.0 12.5 1.2 0.0 0.0 0.0 0.0 9.0 1.0 0.0 0.2 1.6 0.1 1.5 0.0 0.3 17.1 1.0 0.7 2.1 6.6 0.6 0.9 1.9 0.9 0.0 0.1 0.3 0.5 0.2 1.2 0.2 ASB11 DKFZp779E2460 ENSG00000165192 "Ankyrin repeat and SOCS box containing 11" Q8WXH4 X 15281697-15315640 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "heart muscle: 33.4;skeletal muscle: 114.7;tongue: 61.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.7;Ionocytes: 6.1;Melanocytes: 7.2" "Cancer enriched" "Detected in single" 20 "melanoma: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (5.89e-3)" "unprognostic (1.04e-1)" "unprognostic (9.26e-2)" "unprognostic (3.69e-1)" "unprognostic (4.42e-2)" "unprognostic (5.54e-2)" "unprognostic (2.04e-2)" "unprognostic (2.36e-2)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (6.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.7 0.0 114.7 0.8 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 61.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.6 0.2 0.0 0.2 0.2 0.1 8.7 0.0 0.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.4 0.1 0.3 1.7 0.3 0.1 6.1 0.3 0.8 0.3 0.3 0.2 7.2 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.3 0.0 1.9 0.2 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.4 ASCL1 "ASH1, bHLHa46, HASH1" ENSG00000139352 "Achaete-scute family bHLH transcription factor 1" P50553 12 102957674-102960513 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.0;choroid plexus: 13.7;liver: 11.1;pituitary gland: 30.1" "Group enriched" "Detected in some" 5 "Astrocytes: 17.0;Enteroendocrine cells: 36.4;Oligodendrocyte precursor cells: 42.7" "Group enriched" "Detected in many" 6 "glioma: 21.4;lung cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "SCLC-21H: 53.7;SH-SY5Y: 29.0" "Low region specificity" "Detected in all" "HPA029217, HPA076307" Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "HPA029217: AB_10669595, HPA076307: " "unprognostic (7.92e-2)" "unprognostic (4.37e-3)" "unprognostic (4.55e-2)" "unprognostic (5.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.22e-2)" "unprognostic (1.56e-1)" "unprognostic (2.09e-1)" "unprognostic (4.84e-2)" "unprognostic (1.31e-2)" "unprognostic (1.31e-1)" "unprognostic (7.10e-6)" "unprognostic (3.40e-1)" "unprognostic (2.17e-1)" "unprognostic (3.76e-1)" "unprognostic (5.52e-2)" 0.0 1.1 18.7 0.0 18.3 0.0 0.0 18.9 23.0 0.5 13.7 0.1 0.0 0.2 0.0 0.0 0.8 0.0 0.0 18.2 16.8 0.0 11.1 0.5 0.5 20.1 18.1 0.4 0.2 0.0 30.1 0.0 18.5 0.3 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 1.2 0.1 18.7 5.5 0.1 0.0 0.0 0.0 0.3 19.4 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.7 29.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 18.3 18.9 23.0 18.2 16.8 20.1 18.1 18.5 19.9 18.7 19.4 0.1 0.0 0.0 17.0 0.3 0.0 0.3 0.0 0.0 4.3 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.9 0.0 36.4 0.0 1.7 0.0 0.0 0.2 4.6 0.1 0.0 0.0 0.0 1.8 0.1 5.0 4.1 0.0 6.1 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 2.4 0.0 42.7 0.3 0.2 0.0 0.4 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.5 0.2 0.1 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 ASGR1 CLEC4H1 ENSG00000141505 "Asialoglycoprotein receptor 1" P07306 17 7173431-7179564 "Predicted intracellular proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1092.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 1107.9" "Cancer enriched" "Detected in many" 90 "liver cancer: 131.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 115.2;intermediate monocyte: 55.5;myeloid DC: 41.2" "Group enriched" "Detected in many" 8 "dendritic cells: 41.2;monocytes: 115.2" "Cell line enriched" "Detected in some" 29 "Hep G2: 493.2" "Region enriched" "Detected in all" 9 "cerebellum: 44.1" "Not detected" "Not detected" "HPA011954, HPA012852" Enhanced Supported "Vesicles,Cell Junctions" "Secreted to blood" NA NA 10000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Cell Junctions" "HPA011954: AB_1845079, HPA012852: AB_1845080" "unprognostic (3.56e-3)" "unprognostic (3.57e-1)" "unprognostic (8.76e-2)" "unprognostic (4.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-2)" "unprognostic (5.37e-2)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (8.55e-5)" "unprognostic (1.55e-1)" "unprognostic (8.33e-11)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (1.73e-3)" "unprognostic (4.46e-3)" 2.6 1.5 7.7 3.7 7.8 2.5 1.8 17.0 10.9 1.6 7.0 1.2 2.2 1.3 0.6 1.7 1.8 2.9 1.1 7.9 7.6 1.4 1092.3 3.9 1.3 8.0 8.2 1.1 0.9 7.0 2.9 0.5 8.3 1.7 0.5 4.8 0.9 0.3 1.5 4.4 1.4 1.3 6.0 4.8 1.4 26.5 7.8 0.4 5.8 0.4 0.3 1.7 1.5 8.7 0.3 0.7 9.2 4.2 0.0 0.2 0.8 0.8 0.9 0.9 1.6 16.8 0.5 0.3 1.1 0.2 0.4 0.2 0.3 0.2 0.4 0.3 0.8 1.2 1.4 493.2 0.1 0.8 1.7 1.2 0.2 0.5 0.1 0.6 8.4 7.4 1.1 0.6 0.5 0.4 0.7 1.2 1.7 0.2 0.4 0.9 3.5 0.2 0.1 0.7 0.6 3.5 0.7 0.3 0.6 1.5 0.5 0.2 1.2 0.9 3.4 0.7 0.4 0.2 0.3 0.5 0.6 0.4 0.3 10.0 115.2 0.4 0.2 55.5 1.1 0.5 0.2 0.2 41.2 0.5 0.3 0.4 3.3 0.5 14.9 1.8 0.3 36.7 7.7 7.8 17.0 10.9 7.9 7.6 8.0 8.2 8.3 6.0 7.8 8.7 6.0 0.0 4.7 2.9 2.6 3.2 1.7 2.0 3.4 37.8 5.6 6.0 1.5 55.8 2.0 3.7 160.6 3.6 2.9 1.4 3.9 0.9 235.4 4.2 3.6 13.2 15.6 16.8 4.6 0.2 3.7 1.9 3.6 16.5 0.0 5.1 27.5 1107.9 39.9 15.2 4.8 2.3 2.0 97.4 11.9 115.8 2.5 52.6 0.0 1.9 77.2 3.6 0.0 2.0 0.6 0.3 1.3 1.2 0.0 0.9 0.2 6.8 1.6 42.3 0.0 0.8 1.9 6.5 9.7 9.9 4.8 12.4 1.4 1.6 1.3 2.4 ASGR2 CLEC4H2 ENSG00000161944 "Asialoglycoprotein receptor 2" P07307 17 7101322-7115700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "liver: 840.7" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 878.6" "Cancer enriched" "Detected in many" 66 "liver cancer: 214.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "classical monocyte: 110.0;myeloid DC: 64.1" "Group enriched" "Detected in many" 51 "dendritic cells: 64.1;monocytes: 110.0" "Cell line enriched" "Detected in some" 9 "Hep G2: 528.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014899, HPA015998" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 14000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Plasma membrane" "HPA014899: AB_1845085, HPA015998: AB_1845084" "unprognostic (6.76e-2)" "unprognostic (7.45e-7)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (4.99e-2)" "unprognostic (1.16e-3)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (9.74e-2)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (9.35e-4)" "unprognostic (1.54e-3)" "unprognostic (6.95e-2)" "unprognostic (1.86e-1)" "unprognostic (7.31e-2)" 1.5 0.3 0.8 7.9 1.0 7.0 0.5 0.9 1.3 0.4 1.3 0.5 0.3 0.3 0.1 0.5 0.6 17.6 0.5 0.8 1.0 1.2 840.7 2.5 0.9 1.0 1.1 0.2 0.5 0.1 0.2 0.5 1.2 0.4 0.4 0.0 0.5 0.2 0.2 5.2 0.6 1.3 1.0 6.8 0.5 0.5 1.4 0.5 0.3 0.1 1.0 2.0 0.4 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 62.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 528.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.3 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 1.0 110.0 0.8 0.1 11.2 0.2 0.0 0.0 0.0 64.1 0.0 0.1 0.0 1.7 0.1 0.1 1.6 0.3 31.8 0.8 1.0 0.9 1.3 0.8 1.0 1.0 1.1 1.2 1.0 1.4 1.2 0.0 0.0 5.1 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 150.2 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 0.4 0.0 0.0 1.3 7.1 19.6 1.9 0.0 0.2 0.1 0.0 0.1 2.5 0.0 16.1 878.6 8.4 0.0 0.1 0.1 0.0 41.1 7.7 0.7 0.0 19.6 0.0 0.0 15.3 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 6.6 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.3 0.4 1.4 0.0 0.0 0.1 ASIP "AGTIL, ASP" ENSG00000101440 "Agouti signaling protein" P42127 20 34194569-34269344 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 14.8;heart muscle: 28.0;ovary: 41.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.4;dendritic cells: 44.1;Hofbauer cells: 15.1;Leydig cells: 12.5;Peritubular cells: 10.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 356 "plasmacytoid DC: 134.8" "Lineage enriched" "Detected in single" 356 "dendritic cells: 134.8" "Cell line enhanced" "Detected in some" "CACO-2: 3.2;HSkMC: 2.4;SK-MEL-30: 1.9;U-698: 1.9" "Not detected" "Not detected" HPA048636 Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA048636: AB_2680471" "unprognostic (4.81e-2)" "unprognostic (7.46e-2)" "unprognostic (1.97e-3)" "unprognostic (3.26e-2)" "unprognostic (2.24e-1)" "unprognostic (3.07e-2)" "unprognostic (5.13e-2)" "unprognostic (4.57e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (5.53e-6)" "unprognostic (1.02e-1)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" 1.4 0.6 0.2 0.0 0.5 0.3 2.4 0.1 0.4 4.2 0.0 0.5 0.0 2.0 14.8 0.1 4.0 0.1 28.0 0.1 0.1 0.9 1.3 0.3 0.4 0.2 0.1 41.7 0.1 0.0 0.6 0.2 0.6 1.5 0.0 0.3 0.7 0.2 0.9 5.7 0.8 0.0 0.0 0.3 0.3 1.5 0.2 0.2 0.3 1.2 0.5 0.5 1.1 0.3 0.0 1.1 0.4 0.4 0.2 0.7 0.1 0.1 0.0 0.0 0.0 3.2 0.0 1.2 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.7 0.3 0.5 0.0 0.0 0.4 2.4 0.0 0.0 0.0 0.1 0.0 0.7 0.6 0.9 0.0 0.3 0.2 1.7 0.0 0.1 0.6 0.3 0.3 1.4 0.0 0.1 0.2 0.2 0.0 0.2 1.9 0.5 0.3 0.2 0.3 0.5 0.5 0.0 0.3 0.4 0.4 1.9 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 134.8 0.0 0.6 0.2 0.5 0.1 0.4 0.1 0.1 0.2 0.1 0.6 0.0 0.2 0.3 0.4 0.0 0.6 1.3 0.8 2.5 0.0 0.0 0.0 0.0 0.3 0.5 27.4 0.0 0.0 0.0 0.0 0.2 44.1 0.0 1.9 0.0 1.1 0.3 9.2 1.2 0.0 0.0 2.1 0.0 0.2 5.6 0.0 0.4 0.0 0.2 2.5 5.8 15.1 0.0 1.8 0.0 0.0 0.8 7.0 1.7 12.5 2.1 1.8 1.0 0.3 0.0 0.0 2.5 2.5 0.1 0.0 10.5 0.0 0.1 0.0 8.3 0.0 0.0 6.6 0.1 0.6 1.7 1.9 0.2 3.1 0.8 0.6 1.0 0.0 0.1 ASPN "FLJ20129, PLAP-1, SLRR1C" ENSG00000106819 Asporin Q9BXN1 9 92456205-92482506 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 95.3;smooth muscle: 110.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 67.2;Fibroblasts: 94.6;Microglial cells: 24.4;Sertoli cells: 39.5;Smooth muscle cells: 73.5;Suprabasal keratinocytes: 27.0" "Cancer enhanced" "Detected in all" "breast cancer: 51.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enhanced" "Detected in single" "granulocytes: 2.4" "Cell line enhanced" "Detected in some" "ASC TERT1: 16.0;BJ hTERT+: 5.7;HHSteC: 23.2;HSkMC: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007894, HPA008435, HPA024230" Approved Uncertain Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 2100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA007894: , HPA008435: AB_1845112, HPA024230: AB_1845113" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (8.13e-3)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.01e-2)" "unprognostic (9.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-3)" "unprognostic (6.38e-2)" "unprognostic (3.70e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (1.64e-7)" "unprognostic (1.42e-3)" "unprognostic (3.04e-2)" "unprognostic (6.27e-3)" "unprognostic (2.48e-2)" 29.6 7.6 1.2 5.7 1.7 0.1 11.8 2.3 2.0 40.9 0.9 25.5 9.6 69.6 9.7 10.1 16.9 65.9 95.3 1.2 1.2 11.2 41.1 14.3 3.0 1.3 1.2 7.1 13.4 3.8 2.5 4.3 1.6 4.7 11.3 0.2 3.2 11.7 7.8 12.1 17.6 110.5 1.0 2.3 12.0 1.2 1.8 2.5 11.1 19.8 5.5 13.4 5.0 1.7 0.1 0.0 0.0 0.0 1.4 16.0 0.2 2.6 5.7 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 23.2 0.2 0.0 4.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 1.2 1.7 2.3 2.0 1.2 1.2 1.3 1.2 1.6 1.0 1.8 1.7 12.9 0.0 1.1 0.3 0.1 67.2 0.1 0.0 0.0 0.4 0.4 0.1 8.5 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 4.2 6.8 0.0 0.0 2.0 0.0 0.1 94.6 0.5 0.2 1.3 0.1 13.9 0.4 0.2 0.0 1.7 0.0 0.0 0.0 13.5 0.6 5.9 0.8 14.2 24.4 0.0 0.1 0.0 1.5 1.1 0.0 0.0 1.9 0.3 0.0 0.0 0.0 0.7 0.6 39.5 4.3 73.5 0.0 0.1 0.3 27.0 0.0 1.7 0.3 0.0 0.0 ASPSCR1 "ASPL, ASPS, TUG, UBXD9, UBXN9" ENSG00000169696 "ASPSCR1 tether for SLC2A4, UBX domain containing" Q9BZE9 17 81976807-82017406 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 222.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "Hep G2: 298.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026749 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA026749: AB_1845114" "unprognostic (5.01e-2)" "unprognostic (1.19e-3)" "unprognostic (7.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "prognostic favorable (8.55e-4)" "unprognostic (2.02e-1)" "unprognostic (2.07e-2)" "unprognostic (3.43e-1)" "unprognostic (1.71e-3)" "prognostic favorable (2.67e-4)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" 16.5 20.4 16.6 8.4 17.0 15.0 16.9 16.5 20.4 16.2 17.7 16.0 13.6 15.6 7.9 16.8 14.0 7.7 26.1 16.2 15.5 27.3 57.9 17.3 12.2 20.1 16.6 13.4 22.8 14.8 30.6 12.9 18.3 21.6 4.6 5.7 18.3 6.7 44.3 20.5 18.1 5.2 14.7 20.7 22.7 30.0 17.2 8.3 25.9 5.8 6.4 16.0 14.2 21.5 19.3 33.3 13.0 17.9 7.5 9.3 55.4 17.7 12.6 19.3 19.5 20.3 21.3 19.2 18.1 12.4 16.3 9.8 12.0 13.1 6.2 12.9 41.0 21.4 28.7 298.1 25.5 19.1 29.9 10.9 13.9 9.5 6.6 10.0 19.5 16.0 22.0 25.0 11.6 65.0 16.9 41.8 15.5 32.8 23.5 19.2 18.7 39.4 18.0 17.0 32.4 34.8 14.6 42.2 35.2 12.3 27.2 41.4 16.6 35.7 24.5 26.4 22.8 20.2 12.5 21.6 19.2 19.3 21.3 24.0 11.7 8.6 6.6 8.0 3.7 9.0 10.0 8.8 14.7 9.0 7.7 5.8 2.7 8.0 10.4 9.3 5.3 5.6 16.6 17.0 16.5 20.4 16.2 15.5 20.1 16.6 18.3 14.7 17.2 21.5 13.9 9.6 44.7 19.9 24.1 13.4 23.7 24.4 23.3 23.3 19.6 15.6 13.6 27.1 19.8 14.7 41.7 73.7 25.8 29.3 39.2 24.2 49.1 16.2 14.9 16.1 25.0 17.9 12.4 26.2 222.6 17.5 46.9 20.1 21.5 31.0 12.8 56.1 44.7 50.5 12.1 31.5 20.3 26.7 18.6 96.0 11.8 21.7 19.6 1.9 23.8 57.8 19.6 10.6 14.1 17.6 25.8 17.7 27.3 24.9 42.5 58.3 18.5 39.4 13.1 14.7 37.4 41.7 51.0 20.3 14.3 59.4 18.4 23.6 33.3 23.1 ASTE1 HT001 ENSG00000034533 "Asteroid homolog 1" Q2TB18 3 131013875-131027649 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037010, HPA037011" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Endoplasmic reticulum" "HPA037010: AB_10673629, HPA037011: AB_10696929" "unprognostic (7.42e-2)" "prognostic favorable (3.09e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.34e-4)" "unprognostic (2.56e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (4.03e-5)" "unprognostic (2.27e-3)" "unprognostic (2.80e-2)" "unprognostic (1.89e-2)" "unprognostic (2.22e-1)" "unprognostic (1.38e-2)" "unprognostic (2.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.64e-2)" 3.4 3.2 2.9 4.9 3.3 6.7 5.5 6.1 4.8 6.0 3.4 5.4 5.8 3.8 5.9 3.7 4.5 3.9 2.9 3.2 2.5 3.7 6.1 4.1 7.0 2.5 2.8 5.7 3.3 5.0 3.3 3.9 3.0 3.8 5.8 4.7 3.1 4.2 2.3 4.1 7.1 3.4 2.9 4.4 4.7 6.1 3.3 7.2 7.0 2.8 6.8 3.9 2.9 4.6 9.7 7.1 4.5 4.7 7.7 8.4 1.9 5.4 4.6 6.4 7.0 11.4 4.2 10.8 8.2 5.5 5.5 10.5 9.1 4.4 9.6 5.8 5.3 6.4 3.6 5.4 7.9 9.9 3.6 5.3 6.1 5.2 4.9 5.7 5.4 8.7 5.9 5.3 6.7 6.6 9.0 5.2 4.1 11.6 6.8 9.4 6.4 9.4 5.2 5.9 7.7 7.2 10.5 2.4 7.6 4.3 6.3 6.9 3.8 7.2 4.8 12.1 4.3 6.6 6.5 14.0 5.6 8.5 3.6 51.2 13.0 28.4 20.4 15.3 21.3 15.5 22.0 17.7 14.5 16.5 28.3 21.2 9.4 29.4 20.9 10.7 28.2 11.8 2.9 3.3 6.1 4.8 3.2 2.5 2.5 2.8 3.0 2.9 3.3 4.6 6.5 12.8 5.8 7.5 14.6 3.2 3.7 4.8 2.2 9.2 5.1 7.4 1.8 4.3 6.3 3.7 14.6 6.0 17.5 11.1 5.9 4.9 42.1 4.5 5.8 6.9 6.7 6.1 8.3 6.0 4.8 5.1 8.6 4.6 8.8 7.0 10.0 5.6 4.8 3.3 6.3 7.0 4.1 5.7 2.0 12.6 7.2 7.2 1.8 5.6 3.9 5.8 18.6 7.5 10.5 3.6 7.8 4.9 8.7 2.9 15.6 3.5 2.1 13.9 0.0 3.6 6.1 4.4 4.9 3.6 1.4 4.0 15.7 6.1 7.1 2.8 ASTL "ovastacin, SAS1B" ENSG00000188886 "Astacin like metalloendopeptidase" Q6HA08 2 96123850-96138436 "Predicted intracellular proteins" Fertilization "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 4.1;brain: 4.3" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 1.0;Macrophages: 1.2;T-cells: 1.7" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Region enriched" "Detected in single" 5 "cerebral cortex: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RT4: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA015620 Uncertain "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 59: Non-specific - Transcription" "HPA015620: AB_1845121" "unprognostic (3.21e-2)" "unprognostic (1.45e-2)" "unprognostic (3.87e-2)" "unprognostic (3.45e-4)" "unprognostic (1.00e-2)" "unprognostic (3.03e-2)" "unprognostic (3.53e-2)" "unprognostic (5.12e-2)" "unprognostic (3.62e-1)" "unprognostic (3.40e-1)" "unprognostic (1.95e-1)" "unprognostic (2.61e-5)" "unprognostic (3.41e-3)" "unprognostic (1.08e-1)" "unprognostic (1.67e-1)" "unprognostic (9.93e-3)" 0.1 0.0 0.9 0.3 0.2 4.1 0.1 0.7 4.3 0.0 0.0 0.2 0.1 0.1 0.2 0.2 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.2 0.5 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.3 0.1 0.0 0.2 1.0 0.0 0.9 0.4 0.0 0.0 0.7 0.2 0.3 0.0 0.7 0.0 0.0 0.3 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.2 0.7 4.3 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.5 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.5 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 1.7 0.0 0.0 0.0 ATAD5 "C17orf41, ELG1, FLJ12735, FRAG1" ENSG00000176208 "ATPase family AAA domain containing 5" Q96QE3 17 30831966-30895869 "Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 59.3;Spermatocytes: 73.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA066823 Approved "Nucleoplasm,Cytokinetic bridge,Centriolar satellite,Cytosol" "Intracellular and membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA066823: " "unprognostic (3.12e-1)" "unprognostic (7.36e-2)" "unprognostic (1.12e-2)" "unprognostic (1.36e-3)" "unprognostic (3.33e-1)" "unprognostic (1.05e-2)" "unprognostic (1.28e-4)" "unprognostic (1.77e-1)" "unprognostic (1.79e-3)" "unprognostic (7.24e-2)" "unprognostic (2.78e-1)" "unprognostic (3.19e-3)" "unprognostic (6.30e-10)" "unprognostic (3.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.42e-1)" "unprognostic (1.38e-1)" 0.7 0.4 0.3 2.1 0.2 12.3 1.2 2.6 0.5 0.8 0.1 1.2 1.4 1.0 0.4 1.3 0.7 0.5 0.4 0.3 0.2 0.4 0.5 0.8 3.6 0.2 0.1 0.9 0.5 0.3 0.5 1.4 0.3 0.6 1.6 2.5 0.7 0.4 0.4 2.5 1.4 0.6 0.1 1.4 1.1 2.0 0.3 5.3 0.6 0.1 2.9 0.6 0.9 0.6 7.2 6.0 14.0 13.3 0.3 1.4 5.5 6.3 3.2 6.9 9.8 6.6 5.1 19.5 5.9 2.9 4.7 13.0 9.1 4.7 12.4 4.4 7.9 11.7 8.0 4.6 0.2 23.1 9.2 0.6 0.6 10.1 3.5 1.4 3.6 18.7 18.7 15.9 4.6 4.2 26.1 11.5 8.2 5.3 2.9 17.6 26.4 9.3 1.8 7.6 8.1 7.2 7.0 4.0 3.7 7.6 7.6 10.2 2.8 8.3 11.3 12.0 11.4 5.2 5.9 24.0 3.6 10.7 8.4 0.4 0.2 0.3 0.3 0.3 0.2 0.3 0.1 0.2 0.1 0.4 0.2 0.2 0.6 0.6 0.1 0.5 0.3 0.1 0.3 0.2 2.6 0.5 0.3 0.2 0.2 0.1 0.3 0.1 0.3 0.6 4.3 3.2 4.1 6.8 9.9 4.7 3.1 2.6 3.4 19.3 4.7 5.1 2.7 0.0 2.6 3.7 0.0 21.7 10.7 6.6 0.0 4.1 13.9 4.4 8.5 5.4 0.0 59.3 20.4 2.9 21.1 5.4 9.7 5.1 3.8 32.6 2.9 0.7 8.7 11.8 17.4 8.6 2.0 2.8 7.4 7.8 3.7 5.7 7.2 11.2 10.0 2.9 12.3 16.6 14.9 4.0 2.4 2.2 24.4 2.4 2.3 0.5 2.7 21.3 0.0 7.4 6.5 73.3 34.5 9.3 4.5 7.9 10.5 8.4 13.0 2.3 ATAT1 "C6orf134, Em:AB023049.7, FLJ13158, MEC17" ENSG00000137343 "Alpha tubulin acetyltransferase 1" Q5SQI0 6 30626842-30646823 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 87.6;Late spermatids: 42.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 8.0;AN3-CA: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046816, HPA050999" Approved Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" No No "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Golgi apparatus, Cytosol" "HPA046816: AB_2679822, HPA050999: AB_2681303" "unprognostic (3.98e-1)" "unprognostic (3.18e-1)" "unprognostic (4.30e-2)" "unprognostic (2.67e-2)" "unprognostic (8.86e-2)" "unprognostic (8.18e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (1.49e-2)" "unprognostic (5.39e-2)" "unprognostic (2.37e-2)" "unprognostic (1.29e-3)" "unprognostic (1.25e-2)" "prognostic unfavorable (7.78e-5)" "unprognostic (2.62e-2)" "unprognostic (1.51e-1)" "unprognostic (2.02e-1)" "prognostic favorable (1.35e-4)" 5.3 6.0 2.3 0.6 2.9 0.6 7.6 1.8 3.3 12.4 0.9 8.6 0.5 9.7 3.6 7.6 9.8 0.7 5.5 2.6 3.3 11.3 7.6 5.8 0.6 2.3 2.7 13.4 6.0 0.2 21.3 0.4 2.5 13.5 0.6 2.5 7.7 0.3 4.9 6.6 7.8 0.7 1.9 5.6 7.4 13.5 2.5 0.7 9.3 0.0 0.7 9.2 8.4 3.1 1.4 0.7 8.0 5.3 0.9 0.7 0.6 0.3 0.0 0.2 0.4 2.3 1.4 0.1 1.1 1.1 2.2 1.5 2.5 0.9 0.0 1.0 4.2 0.1 0.1 2.6 0.4 0.5 1.1 1.4 0.5 0.3 0.0 1.0 0.5 3.8 1.5 0.0 1.3 1.5 1.0 0.3 0.4 2.2 0.0 1.0 0.1 0.4 1.3 2.4 0.3 3.2 0.6 0.6 0.4 0.0 2.9 0.4 1.0 3.0 1.3 0.0 0.5 0.9 2.5 0.8 1.6 3.4 2.1 0.5 0.4 0.3 0.1 0.3 0.1 0.5 0.2 0.1 0.4 0.2 0.4 0.4 0.3 0.1 0.2 0.5 0.1 0.1 2.3 2.9 1.8 3.3 2.6 3.3 2.3 2.7 2.5 1.9 2.5 3.1 6.2 0.0 1.5 14.7 6.4 5.6 14.0 16.9 14.2 9.0 9.4 11.4 1.9 5.7 8.6 14.7 10.4 11.9 4.1 7.6 7.9 11.9 87.6 9.0 7.7 7.9 18.0 3.0 7.8 4.5 6.3 6.9 8.2 8.0 1.3 16.0 3.3 2.9 6.1 1.7 11.4 8.9 14.2 1.6 3.1 42.4 4.1 3.1 0.0 5.6 9.1 12.5 6.2 16.6 13.1 9.3 10.8 8.6 4.1 11.6 9.7 5.4 10.8 10.7 6.6 8.0 7.8 12.4 11.8 8.0 5.4 8.9 4.7 6.1 11.1 15.3 ATF4 "CREB-2, TAXREB67, TXREB" ENSG00000128272 "Activating transcription factor 4" P18848 22 39519695-39522683 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011596 Approved Supported "Centriolar satellite,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite, Cytosol" "CAB011596: AB_725569" "unprognostic (2.51e-2)" "unprognostic (7.36e-2)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (4.45e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (4.43e-2)" "unprognostic (1.97e-1)" "unprognostic (5.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.41e-1)" "prognostic unfavorable (9.77e-5)" "unprognostic (7.06e-2)" "unprognostic (9.78e-2)" "unprognostic (6.40e-2)" "unprognostic (1.95e-1)" 582.7 408.4 322.1 204.1 337.9 888.2 488.9 349.4 416.4 362.4 319.2 853.9 215.2 389.2 232.2 391.5 381.8 245.6 389.9 316.2 328.3 393.7 492.9 438.0 223.9 353.2 336.7 346.1 629.0 202.6 304.7 247.8 346.6 454.8 218.4 497.5 472.4 278.6 789.2 370.6 362.7 347.4 336.5 351.1 574.5 154.1 339.1 243.7 317.8 420.8 280.6 572.8 363.9 366.3 398.5 230.6 412.3 532.3 450.0 437.1 670.3 470.5 726.2 366.8 462.1 508.5 300.0 760.2 100.7 358.0 300.6 305.1 676.3 551.9 463.7 475.2 461.0 518.9 259.5 516.8 962.7 992.0 479.4 733.3 1172.0 654.3 973.2 658.2 365.8 825.3 560.4 790.7 288.6 241.8 599.2 713.8 354.8 828.1 288.3 612.0 268.5 793.5 491.0 328.0 605.3 254.3 214.8 559.3 1405.8 374.4 342.4 1191.5 290.4 221.5 645.9 250.8 323.8 1004.7 1100.7 888.7 244.9 497.5 506.3 46.5 36.9 24.8 20.0 31.6 26.4 37.9 27.6 26.5 44.3 28.7 28.6 26.6 17.8 26.8 34.9 27.0 31.6 28.8 322.1 337.9 349.4 416.4 316.2 328.3 353.2 336.7 346.6 336.5 339.1 366.3 201.0 169.9 176.0 19.2 181.8 443.9 344.3 171.2 205.5 120.5 286.8 211.5 167.9 143.0 148.7 44.1 93.8 140.1 156.9 357.9 66.5 200.9 20.9 154.2 122.8 229.9 266.7 140.4 19.2 765.1 309.0 198.0 184.5 191.7 223.0 119.0 146.7 190.9 112.7 69.0 16.6 371.4 101.7 174.3 348.4 21.1 185.1 215.7 238.3 22.5 239.5 94.7 92.7 16.6 34.7 396.0 335.7 206.9 223.7 378.5 265.0 85.8 92.3 311.3 335.2 306.5 279.0 72.3 61.5 155.3 335.7 218.4 175.5 115.0 284.5 401.1 ATF5 ENSG00000169136 "Activating transcription factor 5" Q9Y2D1 19 49928702-49933935 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "liver: 2479.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 1412.6" "Cancer enriched" "Detected in all" 7 "liver cancer: 200.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 24.0;intermediate monocyte: 22.4;myeloid DC: 14.3;plasmacytoid DC: 38.5" "Group enriched" "Detected in all" 9 "dendritic cells: 38.5;monocytes: 24.0" "Cell line enhanced" "Detected in all" "HDLM-2: 313.2;Karpas-707: 523.4;THP-1: 452.4;U-266/84: 715.6;U-698: 316.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030187 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm Cytosol "HPA030187: AB_10601666" "unprognostic (2.09e-2)" "prognostic favorable (1.14e-4)" "unprognostic (9.38e-3)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.52e-1)" "unprognostic (6.70e-2)" "unprognostic (3.11e-2)" "unprognostic (2.36e-1)" "unprognostic (4.83e-2)" "unprognostic (2.96e-3)" "prognostic unfavorable (3.39e-7)" "unprognostic (3.06e-2)" "unprognostic (8.06e-2)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" 40.7 61.4 11.7 31.7 11.6 21.4 35.6 10.7 15.2 14.9 9.3 19.6 28.3 16.2 9.8 18.0 22.9 14.4 17.3 12.2 14.7 26.1 2479.9 17.0 23.3 14.5 17.0 14.1 29.1 10.0 14.7 12.3 15.7 23.2 10.3 12.5 21.1 10.3 30.6 17.7 23.2 10.2 13.6 27.3 24.5 44.3 12.4 13.1 118.7 9.5 20.0 24.4 14.3 15.3 68.5 47.3 17.8 12.0 18.3 15.5 17.8 48.6 40.8 49.4 30.2 35.7 36.5 60.7 24.3 28.6 34.0 24.2 22.7 20.0 23.5 313.2 22.6 41.7 14.8 27.4 12.5 162.7 113.6 108.3 31.5 36.5 8.5 12.2 21.4 132.6 38.1 523.4 24.7 64.3 23.5 35.9 8.8 18.6 62.6 194.2 19.1 24.9 56.6 90.9 28.2 20.1 113.2 47.8 34.9 6.6 39.2 452.4 36.6 95.5 61.3 11.3 49.8 13.8 715.6 316.2 75.1 63.6 36.4 0.4 24.0 1.0 1.4 22.4 2.0 1.6 1.4 1.7 14.3 0.8 1.2 1.8 3.6 3.2 6.0 38.5 1.9 4.7 11.7 11.6 10.7 15.2 12.2 14.7 14.5 17.0 15.7 13.6 12.4 15.3 16.3 12.8 11.9 2.6 41.7 22.6 12.3 11.1 39.9 3.8 31.9 29.3 7.4 38.6 9.4 16.5 6.2 33.9 23.5 22.0 13.7 13.1 260.8 36.5 17.4 21.1 21.5 64.2 1.2 29.8 19.4 27.3 34.1 35.3 6.3 27.1 40.0 1412.6 82.5 92.5 1.8 21.0 2.0 59.4 172.3 134.3 13.4 51.2 40.9 2.8 259.9 17.4 8.2 0.5 1.6 20.0 20.6 16.6 118.1 24.8 49.0 47.9 9.6 7.5 13.1 18.0 24.2 15.0 11.3 37.7 24.0 35.6 15.1 23.4 23.4 18.4 ATG2A KIAA0404 ENSG00000110046 "Autophagy related 2A" Q2TAZ0 11 64894546-64917211 "Predicted intracellular proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 16.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038715 Uncertain Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles Nucleoplasm "HPA038715: AB_10673474" "unprognostic (3.05e-2)" "unprognostic (2.33e-1)" "unprognostic (7.55e-2)" "unprognostic (1.18e-1)" "unprognostic (3.42e-1)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.37e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-2)" "prognostic favorable (4.79e-5)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (3.37e-1)" "unprognostic (1.15e-1)" 16.4 20.1 11.4 6.5 10.9 60.2 16.9 8.6 40.1 19.9 11.4 18.9 7.5 18.2 1.8 15.7 19.2 4.2 18.4 11.5 9.8 22.0 59.2 24.2 6.1 13.9 12.3 24.9 22.7 4.9 21.6 4.9 12.7 21.6 2.6 1.9 15.2 5.7 26.7 34.9 21.4 3.3 9.0 25.7 23.2 15.3 11.4 5.4 19.3 4.4 3.3 17.7 15.6 10.4 13.2 12.6 4.4 12.0 5.7 4.0 12.3 7.1 10.3 9.4 6.8 11.0 9.9 9.3 14.7 6.0 12.0 10.8 4.5 8.3 2.5 9.1 15.7 8.7 19.1 10.0 8.4 6.5 18.2 10.9 7.1 11.8 6.3 5.4 7.9 9.5 16.1 7.3 4.1 21.3 7.8 21.9 5.1 3.5 14.3 8.6 7.1 13.5 5.0 10.9 16.5 6.7 10.6 14.6 13.3 3.3 14.3 8.1 10.1 9.0 8.6 18.3 5.3 14.7 5.5 6.5 13.0 5.2 5.6 3.0 2.0 2.2 2.5 2.1 2.1 0.8 1.7 2.2 1.4 0.9 1.3 2.4 16.9 1.8 1.7 2.4 0.9 1.2 11.4 10.9 8.6 40.1 11.5 9.8 13.9 12.3 12.7 9.0 11.4 10.4 9.8 9.6 16.2 20.2 17.0 28.9 8.7 35.7 16.5 16.6 15.8 10.3 8.1 7.2 17.6 9.2 33.3 12.7 40.1 38.8 1.9 10.2 2.5 12.4 9.2 10.2 35.9 16.2 7.6 10.3 5.3 12.6 16.8 24.4 9.5 15.4 7.9 23.2 10.9 13.5 8.4 17.6 24.4 20.1 19.9 3.6 12.8 24.2 30.2 5.6 11.9 12.3 19.6 6.6 7.1 14.9 21.7 10.1 27.3 12.2 26.8 6.6 13.3 26.0 13.1 11.6 10.6 9.0 6.2 16.3 38.4 66.9 40.2 27.2 19.0 15.9 ATMIN "ASCIZ, KIAA0431, ZNF822" ENSG00000166454 "ATM interactor" O43313 16 81035842-81047350 "Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 180.6;Late spermatids: 288.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054967, HPA066900" Approved Supported "Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Nuclear bodies" "HPA054967: AB_2682654, HPA066900: AB_2685744" "unprognostic (9.92e-2)" "unprognostic (3.31e-1)" "unprognostic (4.47e-2)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (9.32e-2)" "unprognostic (4.69e-2)" "unprognostic (1.31e-1)" "unprognostic (1.46e-1)" "unprognostic (6.51e-3)" "unprognostic (1.48e-1)" "unprognostic (4.26e-2)" "prognostic favorable (6.80e-4)" "unprognostic (1.08e-1)" "unprognostic (5.94e-2)" "unprognostic (1.24e-1)" "unprognostic (4.60e-1)" 15.9 12.7 18.9 11.4 19.6 7.9 14.4 18.2 23.5 13.5 14.6 12.9 12.8 13.8 18.0 18.9 11.4 11.5 14.2 19.6 21.6 19.7 17.9 10.7 13.9 19.6 21.7 14.3 16.1 27.0 13.1 20.4 22.8 17.6 13.7 10.3 12.8 14.8 16.0 17.6 12.9 13.7 17.6 12.9 12.7 22.6 21.5 15.6 20.6 17.0 15.0 14.2 12.0 18.4 26.7 22.0 28.6 33.7 30.6 21.3 42.8 17.1 24.8 15.9 8.8 14.9 14.9 20.8 21.8 25.6 18.3 25.3 28.1 14.7 20.3 13.8 15.6 14.3 13.3 17.4 28.3 24.7 21.6 22.7 24.7 15.4 24.7 26.7 16.6 20.0 22.8 12.4 22.9 42.9 19.9 18.0 33.6 16.6 16.3 34.5 13.8 12.2 25.0 27.5 22.8 29.5 54.3 16.8 14.3 23.7 28.5 22.0 22.0 20.3 20.6 19.9 16.2 19.7 31.6 50.4 18.7 16.1 19.3 0.5 0.8 0.5 1.9 0.6 1.4 1.5 2.0 1.7 0.8 1.6 1.7 1.9 0.2 1.9 0.6 1.0 2.2 0.6 18.9 19.6 18.2 23.5 19.6 21.6 19.6 21.7 22.8 17.6 21.5 18.4 38.6 9.6 19.2 10.7 11.7 12.0 16.3 10.0 10.2 24.9 20.7 16.9 18.6 20.0 15.5 23.9 20.9 42.3 25.8 21.4 11.7 12.6 180.6 13.3 37.2 19.3 11.5 7.4 16.1 14.0 38.4 17.9 15.8 22.4 16.5 15.2 22.9 21.6 29.7 13.5 17.7 13.7 6.1 23.9 6.0 288.9 19.9 14.3 14.2 3.7 19.2 32.5 12.3 8.0 16.9 18.5 11.2 19.5 15.0 15.1 19.9 20.8 7.5 16.6 13.1 24.2 18.0 28.6 25.4 17.2 15.3 30.1 15.5 21.6 16.0 18.4 ATP13A1 "ATP13A, CGI-152, FLJ31858, KIAA1825" ENSG00000105726 "ATPase 13A1" Q9HD20 19 19645198-19663676 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031798, HPA049717" Approved Approved Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA031798: AB_2674048, HPA049717: AB_2680858" "unprognostic (2.08e-1)" "unprognostic (4.92e-2)" "unprognostic (4.30e-2)" "unprognostic (7.29e-2)" "unprognostic (3.33e-1)" "unprognostic (4.40e-3)" "unprognostic (3.97e-3)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (2.60e-2)" "unprognostic (1.16e-2)" "unprognostic (9.43e-3)" "prognostic unfavorable (6.51e-4)" "unprognostic (2.26e-3)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.57e-1)" 12.9 17.0 7.3 21.8 6.5 16.1 13.9 5.4 8.6 17.1 12.3 15.6 18.6 16.2 8.0 15.6 15.0 14.0 9.7 7.4 7.9 12.8 12.9 14.0 21.4 7.9 6.5 20.8 21.1 23.4 18.1 12.9 6.9 15.1 13.0 8.8 17.7 12.6 12.8 16.2 22.2 11.6 6.1 26.4 16.7 15.8 7.6 15.9 20.2 5.8 17.5 13.9 14.4 9.0 32.8 45.2 24.3 52.8 38.2 25.3 66.1 28.9 40.1 24.5 24.9 43.5 54.3 44.9 48.6 34.4 14.0 17.8 37.2 37.0 13.4 16.5 77.6 24.6 48.7 34.5 39.3 46.8 70.1 36.7 34.2 26.5 31.8 27.1 17.9 32.1 43.0 97.5 24.7 53.9 31.8 33.7 44.5 40.6 54.7 25.0 17.4 100.9 25.8 44.7 33.4 56.7 26.8 42.6 30.0 11.4 26.9 50.6 28.7 51.5 7.7 59.2 35.3 78.8 50.6 26.8 36.0 59.6 39.5 0.0 3.5 3.5 2.8 5.6 3.1 2.2 3.3 3.1 6.5 1.9 2.1 2.7 0.1 1.4 8.6 5.0 2.9 2.4 7.3 6.5 5.4 8.6 7.4 7.9 7.9 6.5 6.9 6.1 7.6 9.0 11.3 9.6 5.8 12.1 22.7 5.9 7.4 8.2 9.6 12.0 13.0 8.5 5.5 11.5 9.0 14.7 18.8 20.3 12.5 28.5 1.9 19.1 10.3 11.5 9.8 9.0 18.6 11.1 11.2 18.4 18.2 10.2 31.6 13.6 5.7 16.2 10.8 13.2 20.0 5.0 11.0 22.9 12.2 12.2 9.5 5.1 14.0 18.3 7.2 7.5 13.6 12.6 8.2 9.0 11.0 15.6 22.4 9.8 50.4 11.9 28.6 6.6 12.8 10.8 6.6 9.2 11.4 14.7 14.6 12.6 6.1 15.3 13.9 20.2 22.2 6.4 ATP5F1C "ATP5C, ATP5C1, ATP5CL1" ENSG00000165629 "ATP synthase F1 subunit gamma" P36542 10 7788147-7807815 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 895.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 517.1;Distal tubular cells: 890.2;Ductal cells: 453.9;Extravillous trophoblasts: 428.5;Hofbauer cells: 423.4;Proximal tubular cells: 938.6;Theca cells: 413.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060949 Approved NA NA 70000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" "HPA060949: AB_2684395" "unprognostic (1.81e-2)" "unprognostic (8.34e-2)" "unprognostic (3.87e-2)" "unprognostic (1.69e-2)" "unprognostic (2.17e-2)" "unprognostic (1.64e-1)" "unprognostic (2.65e-2)" "unprognostic (8.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.31e-3)" "unprognostic (1.62e-1)" "unprognostic (4.12e-1)" "prognostic favorable (9.26e-4)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (8.30e-2)" "unprognostic (4.08e-2)" 123.7 265.0 82.8 103.2 82.4 149.0 164.8 111.3 111.0 122.5 102.6 240.9 254.7 100.9 150.1 145.9 114.7 112.6 710.9 81.5 94.3 399.9 368.6 93.5 133.0 85.4 83.2 86.8 182.2 411.4 76.7 147.5 86.4 117.5 274.7 161.6 168.3 136.2 537.8 110.7 205.7 146.1 88.8 96.4 174.3 71.1 89.1 192.5 161.7 895.1 175.3 163.8 91.0 90.9 301.2 266.8 255.2 219.3 212.5 276.7 241.2 211.1 176.1 365.7 351.6 511.4 293.8 323.8 163.3 248.0 95.3 337.9 318.3 342.8 325.5 222.3 381.6 351.7 169.3 479.8 172.2 193.6 249.6 222.9 234.1 224.7 134.5 315.7 426.7 321.8 283.4 230.1 352.6 419.0 451.9 217.7 173.3 623.4 201.8 301.9 179.1 460.6 637.5 301.0 141.3 168.2 186.0 417.5 417.1 287.3 437.9 315.9 202.7 151.7 205.3 349.2 229.8 159.2 194.7 265.5 224.7 286.2 127.3 373.0 273.8 241.9 158.5 363.1 185.3 199.2 180.7 174.5 370.4 158.6 146.4 159.6 88.5 226.9 428.2 237.8 261.4 349.3 82.8 82.4 111.3 111.0 81.5 94.3 85.4 83.2 86.4 88.8 89.1 90.9 196.2 118.6 95.4 0.0 30.4 0.0 0.0 0.0 0.0 0.0 156.2 239.3 0.0 0.0 60.7 215.2 0.0 517.1 85.3 0.0 890.2 453.9 0.0 160.9 125.4 76.7 0.0 0.0 0.0 381.8 428.5 89.5 0.0 170.4 97.1 163.2 0.0 0.0 423.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.6 0.0 0.0 140.6 0.0 0.0 0.0 0.0 304.4 0.0 0.0 12.0 0.0 0.0 938.6 64.8 0.0 0.0 0.0 102.0 0.0 0.0 0.0 0.0 371.9 49.1 413.9 0.0 0.0 ATP5MC2 ATP5G2 ENSG00000135390 "ATP synthase membrane subunit c locus 2" Q06055 12 53632726-53677408 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1335.2;Breast myoepithelial cells: 1873.6;Distal tubular cells: 1762.9;Hofbauer cells: 1076.1;Proximal tubular cells: 2061.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051469 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA051469: AB_2681496" "unprognostic (1.48e-1)" "unprognostic (1.06e-1)" "unprognostic (3.01e-1)" "unprognostic (3.37e-3)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (2.97e-3)" "unprognostic (2.29e-1)" "unprognostic (2.83e-1)" "unprognostic (3.45e-3)" "unprognostic (3.78e-2)" "unprognostic (5.71e-2)" "unprognostic (3.32e-3)" "unprognostic (3.41e-1)" "unprognostic (2.22e-1)" "unprognostic (1.42e-1)" "unprognostic (7.09e-2)" 250.6 297.8 487.0 240.0 510.5 445.5 485.5 498.2 574.6 338.4 492.0 444.0 383.6 279.1 463.7 340.5 533.7 296.1 759.6 475.9 499.0 437.4 469.4 243.6 406.4 509.5 488.1 487.2 499.1 503.0 18.9 265.3 507.8 322.2 551.7 275.9 483.0 284.9 1405.5 345.5 322.5 361.1 504.7 295.8 312.1 126.9 500.7 453.9 314.0 1447.2 540.2 365.6 15.2 519.7 325.4 684.8 701.3 640.3 478.0 1162.4 330.7 278.3 630.3 824.5 561.2 236.2 745.1 392.9 668.3 554.8 263.9 304.7 914.6 652.8 729.3 660.9 1096.7 1068.7 515.2 495.7 1034.1 819.7 508.5 1297.4 956.8 797.0 1315.9 1313.7 1078.7 468.0 776.8 1116.6 852.6 857.0 842.8 1996.5 603.6 681.5 756.7 838.3 665.2 981.9 1019.4 407.0 365.8 669.0 376.5 431.6 974.2 610.1 1403.7 1473.7 512.5 396.4 542.2 307.5 441.4 577.6 537.6 288.1 589.9 863.0 620.2 367.7 977.3 281.8 645.6 924.4 710.5 1119.6 826.1 693.6 1324.3 974.6 896.6 755.0 214.2 769.1 849.6 1023.6 955.8 1565.2 487.0 510.5 498.2 574.6 475.9 499.0 509.5 488.1 507.8 504.7 500.7 519.7 412.1 182.7 266.7 0.0 167.8 0.0 0.0 0.0 0.0 0.0 1335.2 1873.6 0.0 0.0 177.0 527.8 0.0 732.4 297.0 0.0 1762.9 470.7 0.0 529.1 446.9 190.2 0.0 0.0 0.0 676.5 777.5 222.2 0.0 454.1 224.5 715.4 0.0 0.0 1076.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.0 0.0 0.0 380.9 0.0 0.0 0.0 0.0 392.7 0.0 0.0 52.8 0.0 0.0 2061.3 215.7 0.0 0.0 0.0 248.9 0.0 0.0 0.0 0.0 507.7 182.6 802.8 0.0 0.0 ATP5PB ATP5F1 ENSG00000116459 "ATP synthase peripheral stalk-membrane subunit b" P24539 1 111448864-111462773 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 135.8;tongue: 131.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 346.5;Distal tubular cells: 461.8;Extravillous trophoblasts: 405.2;Hofbauer cells: 373.0;Proximal tubular cells: 434.6;Syncytiotrophoblasts: 347.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046067, HPA057347" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA 170000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA046067: AB_10960850, HPA057347: AB_2683416" "unprognostic (4.18e-1)" "unprognostic (6.83e-2)" "unprognostic (1.10e-3)" "unprognostic (1.73e-2)" "unprognostic (3.56e-2)" "unprognostic (8.18e-2)" "unprognostic (8.52e-3)" "unprognostic (8.82e-2)" "unprognostic (3.67e-2)" "unprognostic (7.18e-3)" "unprognostic (3.29e-1)" "unprognostic (2.92e-1)" "prognostic favorable (3.26e-9)" "prognostic favorable (8.07e-4)" "unprognostic (1.60e-1)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" 19.3 15.7 10.3 11.5 12.5 15.3 18.8 14.5 27.4 17.4 3.9 51.6 28.8 16.6 16.0 26.8 23.9 16.3 109.0 12.1 10.2 40.3 40.2 13.7 24.0 13.4 12.0 19.2 18.5 33.8 7.1 21.6 14.9 22.3 33.6 28.5 29.8 18.7 135.8 15.7 19.0 17.9 9.6 15.2 22.6 15.5 12.8 15.7 31.1 131.0 22.4 21.9 7.4 14.1 55.6 17.6 44.1 36.9 35.6 34.2 34.1 57.0 68.9 67.3 54.7 31.8 29.1 84.9 52.3 45.5 14.3 56.1 69.4 79.5 65.1 61.9 33.2 76.1 21.3 21.5 26.0 98.3 70.8 30.3 40.9 69.3 66.9 17.7 60.0 11.9 78.7 33.6 46.3 35.4 153.3 30.0 34.9 19.2 90.5 41.2 143.6 34.0 54.7 26.0 37.2 13.4 49.4 72.7 55.6 12.6 54.8 46.0 50.6 32.0 49.1 59.4 61.2 41.8 44.5 172.1 70.8 77.6 60.8 3.5 15.4 7.1 14.8 10.0 12.2 12.9 15.1 13.3 16.1 15.2 16.9 10.4 4.8 9.8 9.0 9.2 15.1 44.2 10.3 12.5 14.5 27.4 12.1 10.2 13.4 12.0 14.9 9.6 12.8 14.1 73.2 67.3 83.8 0.0 31.5 0.0 0.0 0.0 0.0 0.0 112.9 155.3 0.0 0.0 57.6 125.0 0.0 346.5 56.4 0.0 461.8 237.3 0.0 132.5 111.0 58.8 0.0 0.0 0.0 196.7 405.2 57.0 0.0 125.4 89.6 82.1 0.0 0.0 373.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.8 0.0 0.0 98.8 0.0 0.0 0.0 0.0 162.6 0.0 0.0 9.8 0.0 0.0 434.6 74.3 0.0 0.0 0.0 58.0 0.0 0.0 0.0 0.0 347.7 41.8 208.0 0.0 0.0 ATP6AP1 "16A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3" ENSG00000071553 "ATPase H+ transporting accessory protein 1" Q15904 X 154428633-154436516 "Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015218 Uncertain NA NA 700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "CAB015218: " "prognostic unfavorable (2.40e-4)" "unprognostic (1.95e-2)" "unprognostic (2.06e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (1.84e-3)" "unprognostic (4.99e-3)" "unprognostic (2.57e-1)" "unprognostic (1.10e-2)" "unprognostic (1.84e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.07e-1)" "prognostic favorable (5.26e-8)" "unprognostic (2.45e-1)" "unprognostic (4.66e-2)" "unprognostic (3.39e-1)" "unprognostic (1.62e-1)" 56.3 93.5 108.3 43.1 109.2 59.1 56.7 99.6 118.0 59.6 123.6 61.5 48.4 54.2 145.1 85.2 60.0 46.0 92.7 116.2 115.4 104.3 51.4 96.8 46.9 114.0 96.8 63.3 86.6 176.0 110.4 77.9 121.6 85.1 57.0 74.0 87.4 54.8 53.8 83.6 57.4 49.0 104.6 94.7 70.4 47.5 104.2 40.9 81.9 54.4 42.5 63.7 60.9 121.6 110.1 101.6 88.2 146.2 145.7 77.4 162.2 78.5 116.6 122.5 176.1 93.4 135.1 64.7 337.8 177.1 216.5 112.3 133.8 71.9 76.6 58.6 135.1 37.5 113.7 100.0 170.6 60.9 260.2 98.1 126.7 112.4 68.2 139.5 177.0 47.8 45.6 176.4 84.7 158.1 43.6 96.8 32.1 171.0 100.8 66.6 59.1 170.7 139.9 87.3 84.6 89.7 72.6 289.7 159.3 87.3 123.1 157.8 135.5 87.4 79.0 151.1 135.6 256.3 311.8 77.0 104.4 132.8 90.2 246.6 295.1 363.9 147.3 313.8 148.6 91.7 118.4 127.8 376.7 113.6 107.1 117.8 326.9 140.3 255.6 215.9 155.2 216.9 108.3 109.2 99.6 118.0 116.2 115.4 114.0 96.8 121.6 104.6 104.2 121.6 39.4 38.5 57.5 17.0 32.3 30.2 42.7 122.4 25.6 105.8 58.5 42.2 37.7 54.3 102.1 97.5 47.9 145.1 40.1 84.3 19.6 65.4 3.1 52.5 33.7 50.1 89.0 35.8 17.0 52.5 104.5 48.8 36.7 57.4 77.3 51.8 54.3 46.6 246.3 129.5 24.2 59.0 160.7 143.6 88.2 5.5 41.3 130.3 72.9 15.0 79.9 68.4 27.8 22.1 26.4 42.4 67.5 42.5 61.7 34.1 63.7 49.1 112.5 69.2 65.7 35.7 45.5 64.4 10.7 31.6 32.8 196.5 36.3 74.1 54.6 47.2 ATP6AP2 "APT6M8-9, ATP6IP2, ATP6M8-9, M8-9, PRR, RENR" ENSG00000182220 "ATPase H+ transporting accessory protein 2" O75787 X 40579372-40606848 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Congenital disorder of glycosylation, Disease variant, Epilepsy, Mental retardation, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 765.1" "Cell type enhanced" "Detected in all" "Hofbauer cells: 702.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003156 Approved NA NA 140000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA003156: AB_1078245" "unprognostic (1.45e-1)" "unprognostic (3.80e-3)" "unprognostic (1.30e-1)" "unprognostic (7.19e-2)" "unprognostic (8.58e-3)" "unprognostic (1.29e-1)" "unprognostic (1.63e-3)" "unprognostic (2.01e-2)" "unprognostic (1.00e-1)" "unprognostic (4.15e-2)" "unprognostic (1.45e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.01e-5)" "unprognostic (2.34e-1)" "unprognostic (2.08e-1)" "unprognostic (1.62e-2)" "unprognostic (2.86e-2)" 81.2 71.5 85.6 60.6 86.5 124.4 95.1 76.4 116.9 106.1 72.4 82.9 32.1 86.6 91.3 70.1 75.6 79.7 55.1 90.8 90.2 165.6 96.8 87.3 67.4 80.4 79.8 68.9 53.3 765.1 30.7 106.9 83.4 86.6 89.0 99.3 39.4 97.9 18.4 71.9 47.8 124.7 84.6 69.0 49.1 40.4 87.6 72.0 177.1 40.1 72.5 97.7 41.4 98.7 83.9 117.5 78.7 106.7 472.6 312.4 47.9 182.4 274.1 127.0 152.9 68.0 142.6 48.4 88.1 257.0 141.3 86.6 114.0 136.0 168.2 92.7 97.7 57.5 100.2 66.5 172.0 104.6 111.6 259.6 175.2 154.2 121.4 200.3 168.1 46.1 63.8 130.7 201.7 109.8 45.5 93.7 73.4 140.8 112.7 43.8 132.6 161.6 182.8 96.8 55.2 51.9 185.8 111.7 118.4 284.2 147.8 97.1 172.5 175.0 91.3 207.7 62.8 38.0 70.7 46.2 139.1 93.0 138.5 269.0 511.1 404.8 156.1 364.9 164.3 106.7 157.3 161.9 341.3 110.3 174.8 159.3 255.9 141.2 378.6 124.2 167.2 692.9 85.6 86.5 76.4 116.9 90.8 90.2 80.4 79.8 83.4 84.6 87.6 98.7 102.3 57.7 65.6 36.2 65.4 97.3 135.4 254.3 46.1 155.8 74.1 61.2 30.4 94.4 175.4 138.0 54.2 173.4 109.6 70.3 62.6 146.6 3.6 97.2 115.5 94.7 57.1 62.3 44.8 59.1 106.3 156.5 34.7 124.5 87.5 63.7 96.0 64.0 702.2 188.4 56.3 54.6 349.9 279.5 263.3 9.5 117.4 222.0 149.4 28.1 185.4 193.0 72.1 40.2 40.6 64.0 58.9 151.2 74.8 97.9 61.0 106.4 127.4 93.3 105.2 116.7 138.7 106.7 43.1 60.0 99.9 174.4 100.3 188.2 63.6 121.1 ATPAF1 "ATP11, Atp11p, FLJ22351" ENSG00000123472 "ATP synthase mitochondrial F1 complex assembly factor 1" Q5TC12 1 46632737-46673867 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 263.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 284.7;Distal tubular cells: 172.1;Early spermatids: 261.4;Late spermatids: 373.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028382, HPA044950" Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA028382: AB_2672574, HPA044950: AB_2679151" "unprognostic (1.34e-1)" "unprognostic (2.97e-3)" "unprognostic (1.18e-2)" "unprognostic (5.96e-2)" "unprognostic (1.20e-1)" "unprognostic (5.97e-2)" "unprognostic (3.53e-1)" "unprognostic (1.72e-2)" "unprognostic (1.70e-2)" "unprognostic (1.19e-2)" "unprognostic (5.15e-2)" "unprognostic (1.05e-1)" "prognostic favorable (5.33e-7)" "unprognostic (1.36e-1)" "unprognostic (6.52e-2)" "unprognostic (2.44e-1)" "unprognostic (2.62e-1)" 66.0 89.9 87.5 23.3 94.4 27.4 30.2 97.1 115.2 30.0 102.8 44.9 35.3 22.5 29.4 30.1 27.3 25.8 221.0 82.9 107.7 97.1 95.3 21.9 27.9 85.8 85.6 28.8 41.2 121.5 43.8 32.3 85.3 32.2 48.1 63.9 48.4 29.0 221.0 20.1 35.2 32.3 80.7 21.6 42.1 41.5 90.6 37.8 37.1 263.4 28.5 26.4 20.2 82.2 57.8 46.1 61.1 54.8 65.1 52.3 51.0 42.2 52.6 62.0 49.7 37.2 24.5 34.1 55.2 53.6 54.9 43.6 97.3 54.7 83.1 75.0 76.7 60.2 54.5 65.0 52.4 60.2 3.4 51.4 64.3 66.5 57.7 49.2 39.3 62.8 28.2 65.4 48.0 52.3 89.3 33.3 96.3 49.8 68.8 38.1 16.5 74.3 71.4 45.2 71.8 53.8 71.4 74.9 114.6 70.0 69.3 83.8 34.4 21.1 52.1 43.1 58.5 80.6 78.9 23.2 34.7 23.0 40.6 0.0 1.6 4.1 2.1 2.8 2.7 1.8 2.2 2.5 1.6 1.2 3.1 1.4 1.3 5.6 1.2 1.2 4.5 1.2 87.5 94.4 97.1 115.2 82.9 107.7 85.8 85.6 85.3 80.7 90.6 82.2 12.6 3.2 18.6 31.0 22.3 9.4 21.2 9.7 27.3 34.0 27.8 19.4 284.7 31.5 13.1 31.3 27.1 64.0 14.5 26.7 172.1 22.1 261.4 15.6 15.4 13.2 19.2 31.3 37.1 20.1 30.0 28.5 29.0 15.9 15.9 40.6 10.4 39.8 39.2 47.1 48.5 38.1 16.2 21.6 12.9 373.7 19.0 16.1 24.9 15.9 14.6 39.2 15.5 28.1 33.7 11.3 18.0 26.7 36.3 15.2 30.2 119.1 10.2 29.2 26.3 25.1 28.9 45.2 40.4 34.3 13.5 46.9 19.2 55.1 42.2 21.9 ATXN2L "A2D, A2lp" ENSG00000168488 "Ataxin 2 like" Q8WWM7 16 28823035-28837237 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041506, HPA043391, HPA071955" Approved Enhanced Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA041506: AB_2677521, HPA043391: AB_2678459, HPA071955: AB_2686478" "unprognostic (1.64e-2)" "unprognostic (1.72e-1)" "unprognostic (7.33e-3)" "unprognostic (1.03e-2)" "unprognostic (3.11e-1)" "unprognostic (6.63e-2)" "prognostic unfavorable (9.85e-4)" "unprognostic (5.59e-2)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (2.83e-2)" "prognostic unfavorable (7.99e-7)" "unprognostic (1.79e-1)" "unprognostic (1.61e-2)" "unprognostic (7.22e-2)" "unprognostic (2.98e-1)" 67.8 78.2 80.2 51.6 86.2 82.9 65.3 89.9 116.8 83.3 72.7 75.6 43.8 71.3 20.9 81.9 77.8 29.2 68.8 82.2 82.2 85.7 96.1 85.9 62.7 83.2 80.4 81.3 96.8 33.7 116.4 39.0 83.4 80.6 27.0 56.5 70.1 27.9 63.8 76.9 86.3 33.4 75.5 117.0 82.6 178.9 83.5 52.5 83.0 23.7 46.9 75.5 77.7 86.0 77.8 97.6 99.0 112.1 59.9 61.5 116.1 76.3 73.7 82.1 91.3 124.1 90.1 178.6 95.4 54.4 128.6 110.2 93.9 76.9 90.5 140.9 83.3 119.5 124.3 127.4 107.5 135.9 161.2 78.8 90.1 116.4 166.1 72.4 73.2 174.4 158.9 219.9 68.4 109.9 166.1 228.0 100.6 46.9 67.2 216.4 68.5 125.6 48.9 79.6 102.8 81.9 44.6 83.5 95.8 62.3 91.3 141.0 88.2 101.2 83.6 65.8 106.2 311.9 238.1 159.4 76.3 128.1 119.6 0.4 2.1 1.4 1.6 1.9 1.6 4.3 1.9 2.0 1.6 2.9 1.8 2.3 2.4 1.9 1.6 5.6 1.7 1.1 80.2 86.2 89.9 116.8 82.2 82.2 83.2 80.4 83.4 75.5 83.5 86.0 30.2 28.9 33.3 26.1 48.2 36.6 25.1 20.2 66.0 31.6 29.8 26.3 2.1 21.5 19.8 20.2 45.9 23.0 39.1 19.8 1.9 17.8 71.7 37.7 34.9 27.8 24.6 23.1 37.3 20.2 21.9 20.8 31.6 53.1 25.9 23.4 27.1 14.7 24.8 26.9 37.5 23.4 14.2 29.3 33.3 25.7 21.5 36.5 8.8 24.4 26.4 10.0 33.0 18.6 31.5 32.2 19.4 19.9 65.1 33.0 19.7 4.8 18.8 48.9 13.1 28.9 22.1 83.9 28.3 46.3 31.1 34.3 48.4 24.5 23.4 27.4 ATXN7 "ADCAII, OPCA3, SCA7, SGF73" ENSG00000163635 "Ataxin 7" O15265 3 63863155-64003462 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 102.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 15.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034989 Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA034989: AB_10602596" "unprognostic (1.51e-2)" "unprognostic (2.44e-1)" "unprognostic (5.98e-2)" "unprognostic (2.18e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.22e-4)" "unprognostic (9.65e-2)" "unprognostic (2.76e-2)" "unprognostic (2.46e-1)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "unprognostic (9.77e-3)" "unprognostic (2.56e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "unprognostic (3.45e-2)" 7.5 6.3 4.5 11.4 4.1 24.4 7.1 4.9 4.4 7.4 0.2 6.9 8.0 8.6 4.7 8.7 6.3 9.6 5.8 3.1 3.7 7.1 8.4 9.0 12.7 3.4 3.3 8.0 21.0 10.9 2.3 8.3 2.7 6.7 8.8 16.3 7.8 5.2 7.1 9.3 9.2 7.9 0.7 10.6 8.4 15.0 3.1 16.5 7.5 8.7 11.7 7.4 4.4 3.2 8.4 5.7 8.1 7.2 8.5 11.3 9.5 6.5 9.0 11.1 10.5 8.9 8.7 12.5 3.1 9.0 12.5 6.5 9.6 9.1 11.9 22.8 4.9 16.1 10.7 4.2 6.4 8.5 17.7 7.9 9.0 15.7 17.7 9.0 8.4 13.3 6.3 26.2 7.7 25.8 12.7 6.8 5.5 5.7 3.0 9.1 7.1 10.1 6.1 11.0 3.1 5.6 13.2 9.4 10.8 6.4 5.1 12.2 11.9 11.4 12.0 12.7 12.9 12.9 13.2 10.3 10.3 11.6 9.4 15.8 1.1 2.1 3.7 1.0 3.3 1.0 6.2 4.0 0.8 2.4 6.2 4.1 4.5 3.5 0.7 1.5 6.2 1.3 4.5 4.1 4.9 4.4 3.1 3.7 3.4 3.3 2.7 0.7 3.1 3.2 2.4 9.6 9.1 34.6 17.0 43.6 24.9 17.6 29.6 73.2 3.4 1.7 10.5 35.8 17.9 5.5 102.2 14.1 21.5 38.3 0.0 2.8 17.1 3.3 1.5 16.1 26.4 29.5 81.2 4.2 13.6 16.6 18.8 3.5 14.7 1.2 26.7 22.8 14.2 25.2 67.0 19.7 24.4 34.6 30.3 9.5 12.8 20.1 12.4 64.6 33.5 24.5 54.6 60.3 46.7 2.5 28.5 13.2 14.8 26.1 28.1 0.7 27.4 70.8 0.0 39.2 15.6 14.8 15.6 25.6 46.2 61.2 41.5 1.6 20.1 38.6 AUH ENSG00000148090 "AU RNA binding methylglutaconyl-CoA hydratase" Q13825 9 91213815-91361918 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" "Lyase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 191.7;Inhibitory neurons: 137.0;Oligodendrocytes: 137.5;Proximal tubular cells: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004171 Enhanced "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA004171: AB_1845215" "unprognostic (4.10e-2)" "unprognostic (8.95e-2)" "unprognostic (5.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (3.24e-2)" "unprognostic (3.05e-2)" "unprognostic (3.57e-1)" "unprognostic (1.11e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.23e-3)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" 17.2 41.9 11.8 6.3 12.3 4.8 15.9 16.0 15.3 13.6 17.9 17.2 23.8 10.2 14.2 8.6 12.4 10.7 38.9 12.1 14.3 62.9 26.4 10.3 7.6 14.8 13.6 13.4 25.5 45.4 10.4 16.1 15.2 28.2 17.2 21.4 26.1 14.8 24.2 8.7 20.1 8.6 12.2 8.0 22.7 5.5 14.1 9.0 21.0 29.2 7.7 9.1 9.8 15.0 9.1 8.7 12.0 6.2 14.5 15.5 18.5 8.0 10.0 6.1 7.0 5.0 11.4 10.6 8.1 8.5 18.2 13.0 18.1 10.1 8.7 82.6 15.4 7.3 9.7 29.6 11.1 10.6 7.3 13.1 12.5 4.9 16.8 14.3 7.6 10.7 10.3 15.5 7.2 8.8 14.6 23.8 15.0 22.2 12.5 8.5 9.6 18.6 26.6 4.8 12.2 8.8 11.9 28.3 15.6 27.1 5.2 6.9 7.8 6.1 7.6 9.0 7.8 17.7 16.1 3.6 9.6 8.5 4.2 17.9 5.2 18.2 7.2 3.6 8.1 8.4 7.8 10.4 4.6 11.8 9.6 9.1 7.4 10.8 2.5 6.3 10.8 6.5 11.8 12.3 16.0 15.3 12.1 14.3 14.8 13.6 15.2 12.2 14.1 15.0 9.6 0.0 7.7 75.1 11.2 5.2 24.5 27.7 12.5 18.7 15.8 13.5 37.2 27.1 19.1 27.6 25.0 44.6 11.5 27.0 191.7 29.6 3.1 11.5 11.1 11.1 22.9 28.8 101.2 16.1 28.9 14.2 19.4 16.0 1.3 14.5 11.0 18.3 13.4 13.5 137.0 17.3 38.7 8.9 4.7 1.1 14.3 8.9 12.4 67.5 29.1 9.5 18.6 100.5 137.5 12.5 23.5 11.3 18.4 36.8 59.4 120.0 15.8 34.4 13.1 11.9 11.5 8.7 10.5 16.1 4.1 36.4 12.9 11.6 25.0 24.2 AVP "ADH, ARVP" ENSG00000101200 "Arginine vasopressin" P01185 20 3082556-3084724 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Hormone, Vasoactive, Vasoconstrictor" "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1308 "brain: 7951.2" "Group enriched" "Detected in some" 6 "Late spermatids: 26.2;Proximal tubular cells: 46.6" "Not detected" "Not detected" "Region enriched" "Detected in many" 131 "hypothalamus: 7951.2" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.7" "Cell line enriched" "Detected in single" 13 "NB-4: 2.3" "Region enriched" "Detected in many" 10 "hypothalamus: 232.9" "Group enriched" "Detected in many" 337 "basal ganglia: 815.6;hypothalamus: 743.3" "CAB025318, HPA071892" Enhanced Supported "Secreted to blood" NA NA 19300 "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 24: NB-4 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB025318: , HPA071892: AB_2732190" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" 0.3 0.3 24.5 0.0 7.0 0.8 0.2 1.2 60.5 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.3 1.6 7951.2 1.5 0.3 0.1 0.0 0.2 0.7 0.1 0.1 0.0 6.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.1 1.7 0.1 0.0 1.0 0.0 0.0 1.4 10.8 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 24.5 7.0 1.2 60.5 1.6 7951.2 0.2 0.7 0.3 1.0 10.8 0.5 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 1.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 5.7 0.0 0.2 0.0 0.0 4.2 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.1 0.0 5.0 0.2 0.0 0.0 0.0 0.3 26.2 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.3 46.6 0.0 0.1 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 AXIN2 "DKFZp781B0869, MGC126582" ENSG00000168646 "Axin 2" Q9Y2T1 17 65528563-65561648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 33.7;Extravillous trophoblasts: 102.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 33.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 27.2;CACO-2: 52.3;Hep G2: 78.8;OE19: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012283, CAB017783" Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Cytosol "CAB012283: AB_2290204, CAB017783: " "unprognostic (1.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.48e-1)" "unprognostic (9.81e-2)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (4.57e-2)" "unprognostic (8.84e-3)" "prognostic favorable (6.58e-4)" "unprognostic (1.98e-1)" "unprognostic (1.42e-1)" "unprognostic (3.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.74e-1)" "unprognostic (1.25e-1)" 8.7 10.9 6.8 5.4 6.9 0.9 5.3 7.9 7.9 17.2 5.5 12.3 7.1 23.9 5.9 5.9 19.8 6.6 8.0 9.4 6.2 3.7 2.7 17.0 3.5 8.5 7.9 15.0 4.2 4.2 6.2 18.4 5.3 14.0 14.6 3.4 5.2 8.9 14.6 14.9 7.4 17.3 7.3 7.4 13.6 6.7 11.0 17.3 12.3 7.8 2.7 11.4 8.0 5.6 0.0 13.9 27.2 0.5 9.6 4.1 12.0 0.4 1.3 0.9 1.7 52.3 5.0 1.0 1.7 8.0 1.0 0.4 5.7 0.1 1.9 2.4 3.1 0.0 2.4 78.8 1.0 0.1 0.1 2.4 2.1 2.2 0.6 1.6 2.4 5.1 0.2 1.2 1.4 0.3 13.9 0.1 5.3 86.9 0.6 9.9 1.6 0.1 2.6 0.3 8.4 5.5 0.5 0.3 4.8 20.0 1.0 0.3 6.3 5.3 9.6 7.6 1.7 0.1 3.0 3.8 2.5 0.6 2.6 3.2 0.0 0.0 0.1 0.0 0.4 0.5 1.1 0.2 0.0 1.8 2.3 0.4 0.0 1.0 0.0 0.0 0.0 0.3 6.8 6.9 7.9 7.9 9.4 6.2 8.5 7.9 5.3 7.3 11.0 5.6 2.4 0.0 9.0 9.8 1.0 11.2 2.2 1.0 11.4 3.7 5.2 8.1 8.7 1.5 8.1 0.0 4.2 18.1 0.7 15.2 0.0 1.4 33.7 7.8 15.1 5.3 5.4 0.0 8.4 0.9 102.6 10.3 5.6 16.5 0.0 3.1 1.1 2.0 3.8 1.7 8.7 17.4 0.0 0.0 7.5 17.5 6.5 0.6 17.8 9.4 1.0 3.3 0.0 8.0 2.0 0.8 18.9 10.9 0.9 2.9 1.9 0.9 1.3 2.5 13.1 1.6 10.6 6.2 12.9 3.3 5.5 14.2 4.6 3.6 19.8 1.3 AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2809.6;salivary gland: 3847.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1315.5;Breast myoepithelial cells: 704.8;Hepatocytes: 4270.8;Ionocytes: 901.3;Prostatic glandular cells: 1691.9;Urothelial cells: 674.2" "Group enriched" "Detected in many" 12 "breast cancer: 412.6;liver cancer: 273.6;prostate cancer: 469.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 56.6;OE19: 158.9;RPMI-8226: 130.4;T-47d: 41.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 55200000000 74000000000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "CAB016087: AB_667849, CAB032276: AB_2062580, HPA012582: AB_1845226, HPA012876: " "unprognostic (8.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.41e-1)" "unprognostic (5.42e-3)" "unprognostic (4.98e-2)" "unprognostic (5.74e-3)" "prognostic favorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (2.35e-2)" "unprognostic (1.79e-1)" "prognostic favorable (1.53e-4)" "unprognostic (2.18e-1)" "unprognostic (2.08e-2)" "unprognostic (9.80e-2)" "unprognostic (3.51e-3)" 128.6 3.9 17.1 2.7 28.8 0.4 1061.4 23.1 18.8 3.4 16.0 6.7 30.9 1.5 2.5 22.0 3.0 38.7 114.7 14.9 22.2 326.8 2809.6 14.8 0.4 20.2 23.3 6.0 752.1 0.1 1.3 0.5 27.1 1051.4 4.2 3.6 3847.3 40.2 1.7 206.8 28.6 0.3 14.0 1.4 315.2 25.9 21.4 0.8 1.9 2.3 1.5 5.8 7.5 24.5 0.2 0.0 0.0 0.0 11.3 0.0 5.5 0.0 0.0 0.0 0.0 0.1 4.0 14.2 0.7 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.3 0.1 56.6 4.9 1.5 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.3 29.9 0.0 0.0 0.0 5.1 0.2 158.9 0.0 0.0 1.7 130.4 0.0 0.0 0.0 2.0 1.0 25.4 13.0 0.0 41.8 0.0 0.0 0.5 0.1 1.8 0.9 1.9 0.8 0.4 0.0 0.5 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 28.8 23.1 18.8 14.9 22.2 20.2 23.3 27.1 14.0 21.4 24.5 9.9 22.4 276.8 0.0 14.7 4.2 422.1 25.3 0.0 0.0 1315.5 704.8 115.9 451.8 63.0 5.5 2.1 0.0 10.4 5.5 46.9 11.7 1.9 1.4 1.2 14.2 12.4 85.5 0.1 254.2 0.0 7.7 94.8 5.5 3.8 1.2 65.3 4270.8 0.0 0.0 0.1 13.1 901.3 93.1 0.7 4.2 0.9 14.8 62.2 1.0 2.0 23.7 0.0 7.5 7.3 221.5 6.4 0.0 0.3 1691.9 15.3 596.1 6.3 0.3 0.0 0.0 11.9 7.4 0.4 9.9 9.7 0.0 12.3 0.1 12.6 674.2 AZU1 "AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC" ENSG00000172232 "Azurocidin 1" P20160 19 825097-832018 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Heparin-binding, Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "bone marrow: 1578.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.5;Breast myoepithelial cells: 4.6;Endometrial ciliated cells: 8.9;Erythroid cells: 8.8;Respiratory ciliated cells: 4.5;Skeletal myocytes: 5.7;Spermatogonia: 6.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "neutrophil: 3.3" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.3" "Cell line enriched" "Detected in some" 15 "THP-1: 659.5" "Not detected" "Not detected" "HPA055851, HPA075964" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 320000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA055851: AB_2682943, HPA075964: " "unprognostic (1.12e-2)" "unprognostic (3.71e-2)" "unprognostic (4.44e-2)" "unprognostic (8.85e-3)" "unprognostic (1.62e-2)" "unprognostic (1.29e-1)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (3.32e-1)" "unprognostic (4.22e-3)" "unprognostic (2.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-6)" "unprognostic (1.11e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-2)" "unprognostic (3.04e-2)" 0.8 0.2 0.4 0.0 0.4 1578.1 1.5 0.2 0.9 0.2 0.2 0.2 0.0 0.5 0.0 0.1 1.4 0.0 2.0 0.4 0.3 0.4 2.8 15.9 0.6 0.3 0.3 0.2 0.2 0.0 0.9 0.9 0.4 0.4 0.0 0.0 2.6 0.0 0.5 0.6 0.2 0.0 0.2 33.1 0.2 2.4 0.4 3.1 0.5 0.0 0.0 0.3 0.2 0.3 1.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 44.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.4 0.6 659.5 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.6 0.0 34.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 0.1 0.4 0.4 0.2 0.9 0.4 0.3 0.3 0.3 0.4 0.2 0.4 0.3 3.5 0.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.0 4.5 4.6 0.7 0.0 0.5 0.0 0.0 0.2 2.8 0.6 0.0 0.1 0.0 8.9 1.2 1.0 0.0 8.8 0.8 0.0 0.3 0.8 0.0 2.3 0.0 0.1 0.0 0.4 3.2 0.0 1.4 0.4 0.0 3.7 0.4 0.7 0.0 3.2 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.2 0.0 4.5 0.0 0.0 5.7 1.2 0.1 6.4 0.9 0.1 0.0 1.0 0.0 0.6 0.0 B2M ENSG00000166710 Beta-2-microglobulin P61769 15 44711487-44718851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Immunity "Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 31919.3;NK-cells: 24726.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002572, HPA006361" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1790000000 2100000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus, Plasma membrane" Cytosol "CAB002572: AB_563434, HPA006361: AB_1078278" "unprognostic (9.45e-2)" "unprognostic (5.63e-2)" "unprognostic (3.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.18e-1)" "unprognostic (4.82e-2)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (2.44e-3)" "unprognostic (2.02e-2)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (5.25e-2)" "unprognostic (1.97e-2)" "unprognostic (2.17e-2)" 3160.2 3214.7 697.6 5686.5 705.1 7839.2 2606.9 711.8 1145.0 2539.9 789.6 5139.0 5180.7 2192.2 1735.6 2283.9 1648.3 4948.8 2327.2 651.0 769.9 2462.6 6206.2 6159.2 9311.8 889.5 763.2 1945.7 1310.9 1940.5 318.4 3502.0 815.3 2345.0 5593.5 139.3 5657.1 1784.5 931.7 3015.6 5693.3 2545.3 838.3 7896.1 4878.2 615.6 771.9 4217.4 2340.8 2026.5 5333.4 5753.1 549.4 909.5 1735.4 378.9 226.0 633.6 4348.7 4719.4 1662.5 2045.5 4961.9 3609.7 6561.4 425.3 5417.9 554.8 2567.9 1948.8 2410.2 2537.0 497.2 878.7 1226.2 4762.2 435.9 2956.9 2263.6 600.3 3609.3 2074.5 3328.6 2735.9 609.8 1075.7 1044.4 2442.6 1884.1 965.4 611.9 3649.1 2195.5 476.9 1518.4 3213.8 206.5 629.8 1014.3 2240.2 1926.6 4789.2 2425.5 3486.4 254.1 179.1 1288.4 1571.2 1338.5 394.3 655.3 6180.6 2548.7 4531.4 676.5 5389.2 2193.3 4771.7 7118.6 1683.1 5384.6 3783.6 2567.3 48105.4 18117.1 33178.9 20639.1 17775.0 20836.8 15768.0 23783.0 22245.1 9978.8 11988.4 17122.9 22791.8 50453.6 18779.6 19034.9 12052.6 29659.1 56957.2 697.6 705.1 711.8 1145.0 651.0 769.9 889.5 763.2 815.3 838.3 771.9 909.5 12048.3 3387.8 3505.1 28.7 8472.8 7843.7 3197.1 8420.8 1628.8 33.3 2399.5 2015.2 1068.8 3593.1 5347.4 2100.3 27.1 1354.6 14028.8 8753.6 1038.9 13898.6 43.1 2073.7 2414.0 8385.6 2266.0 2087.2 7.3 9034.5 4397.5 3691.1 1981.7 2282.2 3029.5 1270.6 6835.7 3832.6 11985.7 5.0 22.0 5982.6 8701.4 12536.8 14507.0 158.8 3018.0 10687.9 6744.8 368.2 31919.3 322.0 24726.3 95.0 129.2 10115.7 7085.6 1688.8 11026.6 5300.4 18327.7 3122.5 8367.9 52.5 4016.7 2055.2 4107.1 64.2 72.1 1541.4 8619.8 804.8 14266.2 3229.8 3063.4 8248.6 B3GALNT1 "B3GALT3, beta3Gal-T3, galT3, GLOB, P1" ENSG00000169255 "Beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)" O75752 3 161083883-161105411 "Blood group antigen proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 53.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 56.3;Cardiomyocytes: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 8.8;NK-cell: 22.1" "Group enriched" "Detected in many" 7 "granulocytes: 8.8;NK-cells: 22.1" "Cell line enhanced" "Detected in many" "RT4: 128.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041204 Approved Vesicles NA NA 400000 "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA041204: AB_10795585" "unprognostic (3.85e-2)" "unprognostic (5.11e-3)" "unprognostic (3.02e-1)" "unprognostic (1.06e-2)" "unprognostic (7.83e-2)" "unprognostic (4.07e-2)" "unprognostic (9.26e-5)" "unprognostic (1.49e-2)" "unprognostic (1.12e-2)" "unprognostic (1.88e-2)" "unprognostic (3.44e-2)" "unprognostic (3.24e-1)" "unprognostic (2.09e-3)" "unprognostic (1.32e-1)" "unprognostic (4.90e-2)" "unprognostic (3.66e-2)" "unprognostic (3.19e-3)" 5.3 7.2 20.7 3.9 21.5 4.8 9.8 14.7 19.6 20.1 8.0 2.7 1.9 9.9 8.5 6.8 14.2 9.9 53.3 21.7 26.7 19.4 1.2 14.6 4.9 12.8 21.7 18.8 11.1 8.6 9.8 13.9 18.0 11.6 2.4 26.6 22.3 8.5 1.4 2.5 2.4 9.9 14.1 6.2 10.7 8.4 25.7 2.8 27.0 3.2 5.4 12.3 5.4 13.0 17.3 0.3 7.5 0.1 1.0 2.8 0.1 9.3 8.7 22.3 7.3 11.3 13.2 0.0 35.7 8.0 12.7 3.9 0.0 16.9 7.5 0.0 0.0 9.0 5.7 0.0 11.2 0.2 0.0 23.3 5.4 6.1 1.4 15.6 31.6 0.0 0.0 0.0 8.3 29.4 0.1 0.0 17.4 0.2 38.9 0.1 0.0 0.2 9.3 128.3 15.1 0.1 23.7 8.8 6.3 3.0 35.6 13.3 0.0 0.2 15.5 0.5 0.2 3.6 0.1 0.2 14.7 0.0 0.0 8.8 0.2 0.0 0.4 0.2 0.4 2.3 0.2 0.4 1.7 0.2 0.4 0.9 0.4 22.1 0.1 1.1 0.0 0.7 20.7 21.5 14.7 19.6 21.7 26.7 12.8 21.7 18.0 14.1 25.7 13.0 5.0 19.2 2.2 10.1 2.1 5.0 5.2 5.7 6.2 56.3 7.5 6.2 56.9 0.0 8.0 14.7 12.5 21.2 1.2 0.1 11.7 3.5 0.7 4.9 5.8 7.7 1.8 17.0 22.3 8.5 13.0 13.3 4.6 8.7 10.2 13.0 6.1 0.2 9.8 6.7 27.5 0.1 6.1 2.1 6.8 2.2 7.2 3.4 10.6 9.4 4.3 12.6 1.0 14.6 3.2 9.8 0.1 5.3 0.2 6.2 0.1 15.8 3.1 8.4 0.0 5.3 13.2 6.5 20.7 8.4 2.6 5.1 1.2 4.6 0.7 4.5 B3GALNT2 MGC39558 ENSG00000162885 "Beta-1,3-N-acetylgalactosaminyltransferase 2" Q8NCR0 1 235447190-235504452 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Cone photoreceptor cells: 252.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007846, HPA050662" Approved Uncertain "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA007846: , HPA050662: AB_2681209" "unprognostic (5.50e-2)" "unprognostic (3.16e-3)" "unprognostic (6.60e-2)" "unprognostic (1.63e-1)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (7.59e-3)" "unprognostic (1.96e-2)" "unprognostic (3.39e-2)" "unprognostic (3.38e-1)" "unprognostic (7.19e-3)" "unprognostic (2.89e-1)" "unprognostic (1.99e-1)" "unprognostic (5.52e-2)" "unprognostic (3.40e-1)" "unprognostic (3.53e-3)" "unprognostic (8.34e-3)" 4.7 5.4 2.3 2.8 2.2 1.6 4.0 2.5 2.4 5.3 5.7 8.1 3.2 7.3 4.8 8.9 5.5 5.3 6.1 2.4 2.6 3.3 3.2 3.4 2.2 2.4 2.7 5.1 22.3 6.7 3.8 4.3 2.3 7.3 5.3 3.9 6.0 6.6 23.3 6.2 5.1 10.6 2.3 2.7 8.9 5.9 2.5 3.6 7.3 16.7 3.4 7.9 5.4 2.2 15.0 10.4 11.1 16.2 14.2 15.7 21.6 14.1 11.8 9.8 10.0 7.7 13.1 8.2 15.3 15.5 7.0 17.3 21.3 14.8 12.5 14.5 11.7 5.8 12.7 9.3 10.0 17.9 4.3 9.9 9.5 10.4 21.5 7.0 14.1 19.2 10.9 10.9 9.2 7.3 10.0 8.8 15.7 7.9 3.1 10.6 19.9 18.8 6.4 21.1 14.2 16.8 23.7 7.8 12.2 3.9 18.5 15.6 13.1 9.7 13.3 16.6 18.1 11.3 14.8 5.0 6.7 12.1 21.7 1.1 1.1 0.5 0.6 1.6 0.8 0.6 0.6 0.7 2.3 0.5 0.5 0.9 0.2 1.2 1.4 1.9 0.3 0.4 2.3 2.2 2.5 2.4 2.4 2.6 2.4 2.7 2.3 2.3 2.5 2.2 9.6 9.6 5.0 38.8 7.8 31.2 39.0 15.1 36.5 33.1 8.9 6.7 6.7 1.5 9.5 5.5 252.3 20.3 14.6 5.2 0.0 6.9 26.7 20.2 14.8 7.0 9.0 5.0 38.4 7.2 7.0 11.5 10.7 19.9 5.7 11.9 4.6 4.7 3.9 28.6 56.2 6.2 4.1 3.0 16.3 7.3 10.5 6.9 1.8 23.4 11.5 11.2 7.2 29.1 21.7 9.2 5.4 16.1 14.0 27.6 9.7 2.3 8.1 18.4 0.0 21.0 20.5 35.8 40.3 28.5 29.7 22.4 9.0 17.6 7.0 33.1 B3GALT1 beta3Gal-T1 ENSG00000172318 "Beta-1,3-galactosyltransferase 1" Q9Y5Z6 2 167868948-167874041 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;skeletal muscle: 5.2;tongue: 17.8" "Group enriched" "Detected in some" 6 "Astrocytes: 920.7;Excitatory neurons: 519.3;Inhibitory neurons: 723.8" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "AN3-CA: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.22e-2)" "unprognostic (1.67e-1)" "unprognostic (4.23e-3)" "unprognostic (2.49e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-1)" "unprognostic (3.94e-2)" "unprognostic (8.72e-2)" "unprognostic (6.44e-2)" "unprognostic (2.30e-3)" "unprognostic (8.34e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (3.79e-1)" 0.2 0.5 4.0 0.2 5.4 0.1 0.4 2.0 5.8 0.3 0.0 3.6 0.0 0.2 0.4 0.1 0.6 0.0 0.0 5.8 3.0 0.1 0.0 0.1 0.0 2.4 2.9 0.2 0.3 0.0 1.8 0.0 1.4 0.2 3.6 2.4 0.2 0.7 5.2 0.2 0.2 0.2 2.0 0.2 0.0 0.5 2.6 0.0 0.2 17.8 0.0 0.0 0.2 3.4 0.0 0.0 2.8 35.7 0.3 0.0 0.0 0.5 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.0 4.6 0.0 1.2 0.0 0.2 0.0 0.5 0.0 2.3 0.4 0.0 0.0 0.7 1.6 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.0 0.8 0.0 0.7 0.0 3.3 0.5 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.3 0.2 0.2 0.1 0.0 0.1 0.1 0.0 4.0 5.4 2.0 5.8 5.8 3.0 2.4 2.9 1.4 2.0 2.6 3.4 0.2 0.0 1.3 920.7 0.2 0.1 0.0 0.0 0.0 3.0 0.1 2.4 0.8 0.0 0.0 0.0 0.0 0.0 0.1 18.3 0.0 0.1 0.5 0.1 0.6 0.7 0.0 0.0 519.3 0.2 0.0 0.5 0.0 0.4 1.3 0.0 0.0 0.0 0.1 1.7 723.8 3.8 0.0 0.0 0.3 0.0 0.6 0.3 1.8 39.4 0.0 2.4 0.0 108.0 30.3 0.0 3.4 1.5 0.0 0.4 0.0 0.4 0.0 1.3 0.0 1.1 0.6 0.0 1.7 0.0 0.0 0.0 0.1 0.1 7.4 0.1 B3GALT4 "beta3Gal-T4, GalT4" ENSG00000235863 "Beta-1,3-galactosyltransferase 4" O96024 6 33277123-33284832 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.9" "Cell type enhanced" "Detected in many" "Late spermatids: 71.8;Spermatocytes: 81.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 4.0;MOLT-4: 1.1;SCLC-21H: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043001 Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA043001: AB_2678265" "unprognostic (3.71e-2)" "unprognostic (1.33e-2)" "unprognostic (6.02e-2)" "unprognostic (1.00e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-2)" "unprognostic (6.00e-2)" "unprognostic (2.17e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.98e-2)" "unprognostic (1.96e-1)" "unprognostic (1.17e-3)" "unprognostic (6.83e-2)" "unprognostic (1.94e-1)" "unprognostic (1.22e-2)" "unprognostic (3.75e-2)" 9.3 8.8 0.4 0.0 0.8 0.0 8.0 1.8 1.2 8.5 0.5 11.7 0.0 8.1 0.0 19.5 6.5 0.0 8.5 0.2 0.4 7.0 1.5 7.6 0.0 1.5 0.9 3.5 3.4 0.0 5.6 0.0 1.2 9.0 0.0 0.0 12.4 0.0 2.5 15.2 10.8 0.0 0.8 12.8 9.5 27.9 0.8 0.0 7.3 0.0 0.0 9.7 11.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 7.7 4.6 2.4 1.8 1.8 1.8 3.1 2.5 8.8 1.8 2.4 2.8 5.0 5.7 4.7 4.5 2.0 0.4 0.8 1.8 1.2 0.2 0.4 1.5 0.9 1.2 0.8 0.8 1.3 12.6 12.8 4.8 1.3 12.0 3.2 6.3 18.9 4.0 14.5 7.6 4.2 3.8 15.7 18.9 14.7 4.2 18.4 20.2 38.2 5.9 17.7 36.8 12.1 3.1 11.1 12.6 5.2 1.0 18.4 12.9 8.2 13.3 11.0 10.2 5.0 15.0 0.4 20.3 11.8 1.4 15.8 16.2 22.3 8.6 71.8 7.8 15.2 8.8 4.7 27.2 9.8 54.6 1.5 2.1 20.0 32.6 6.0 6.2 9.1 35.5 6.1 26.0 15.0 6.6 3.3 5.9 81.2 2.7 13.2 4.8 32.0 14.2 5.1 11.2 17.0 B3GALT5 "B3GalT-V, B3T5, beta3Gal-T5, GLCT5" ENSG00000183778 "Beta-1,3-galactosyltransferase 5" Q9Y2C3 21 39556442-39673137 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 196.4;Intestinal goblet cells: 47.4;Paneth cells: 72.5;Proximal enterocytes: 94.1;Undifferentiated cells: 57.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 23.5;RPTEC TERT1: 27.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.6" "HPA054092, HPA054684" Approved "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA054092: AB_2682375, HPA054684: AB_2682573" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "prognostic favorable (6.36e-4)" "unprognostic (9.23e-2)" "unprognostic (4.62e-2)" "unprognostic (4.06e-2)" "unprognostic (2.04e-1)" "unprognostic (2.48e-1)" "unprognostic (3.25e-2)" "unprognostic (7.86e-3)" "unprognostic (1.67e-1)" "unprognostic (6.09e-4)" "unprognostic (1.12e-1)" "unprognostic (2.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" 0.0 0.3 2.5 0.9 8.6 0.0 2.6 0.7 3.7 2.2 1.9 22.4 27.3 0.7 1.3 1.6 1.3 5.5 0.0 2.4 4.6 0.2 0.1 0.1 0.0 2.0 2.1 0.3 3.3 0.0 1.8 0.0 1.3 0.4 37.4 0.8 4.5 0.1 0.0 0.8 33.7 0.8 1.3 0.0 5.0 0.4 6.9 1.0 1.2 0.3 2.0 1.3 2.3 0.7 0.0 0.9 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 23.5 0.0 0.2 0.2 2.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 6.3 0.2 0.6 0.0 2.7 0.1 27.1 1.7 4.6 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.7 0.2 1.0 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 8.6 0.7 3.7 2.4 4.6 2.0 2.1 1.3 1.3 6.9 0.7 0.1 0.0 0.0 6.5 0.3 0.0 0.5 0.1 0.0 7.4 8.0 8.1 2.2 10.0 5.3 5.5 0.0 0.0 0.2 196.4 0.0 7.5 0.4 0.2 5.9 0.4 28.9 0.0 3.6 4.7 0.0 0.2 13.3 0.2 4.5 0.8 0.0 0.0 0.0 0.0 4.8 47.4 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 1.4 0.0 11.1 1.0 9.2 72.5 0.0 0.0 0.6 94.1 0.1 1.5 0.2 0.0 0.1 0.4 0.1 1.7 0.5 0.0 0.0 0.5 0.0 57.7 9.7 B3GALT6 beta3GalT6 ENSG00000176022 "Beta-1,3-galactosyltransferase 6" Q96L58 1 1232237-1235041 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SCLC-21H: 69.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 14000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 52: Non-specific - Transcription" "unprognostic (9.76e-2)" "unprognostic (6.97e-2)" "unprognostic (4.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-1)" "unprognostic (4.62e-2)" "unprognostic (2.65e-3)" "unprognostic (1.86e-1)" "unprognostic (1.37e-1)" "unprognostic (2.66e-1)" "unprognostic (3.08e-2)" "unprognostic (2.40e-2)" "unprognostic (1.85e-1)" "unprognostic (1.54e-1)" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (9.89e-2)" 8.7 8.7 8.9 5.6 9.0 1.8 8.4 7.3 9.9 7.6 7.3 6.5 3.9 10.7 3.8 7.2 7.7 3.7 10.1 9.5 10.1 9.9 13.5 6.8 6.2 10.4 9.3 7.0 11.9 7.8 9.3 5.2 8.8 8.0 3.0 2.4 6.4 4.2 9.3 9.2 6.5 4.8 8.3 10.3 7.8 5.4 9.0 5.8 7.7 4.8 3.7 7.6 6.3 9.3 20.4 10.2 17.0 17.9 16.8 11.3 13.2 21.2 17.9 17.4 14.1 9.1 20.3 15.1 12.4 12.7 15.2 17.9 7.4 11.4 10.6 26.8 28.2 28.2 10.1 8.7 17.3 17.6 17.1 10.6 8.3 11.6 11.3 10.5 13.3 17.2 20.0 13.2 18.0 11.6 24.0 31.6 21.9 21.2 37.9 22.8 6.7 12.5 17.4 6.1 69.6 28.6 15.8 18.4 11.4 9.9 15.4 24.9 14.4 17.9 7.9 11.3 30.9 8.2 7.6 14.0 14.1 38.9 20.8 1.3 1.2 0.4 1.6 1.6 2.8 1.4 1.6 1.9 1.7 2.3 1.4 1.7 0.6 2.9 2.0 2.3 0.7 1.0 8.9 9.0 7.3 9.9 9.5 10.1 10.4 9.3 8.8 8.3 9.0 9.3 15.6 12.8 9.9 3.9 13.7 8.4 31.1 3.8 2.2 13.1 15.4 17.5 8.4 11.5 3.4 12.9 4.2 1.7 20.9 3.8 7.9 8.1 0.6 7.6 16.0 12.5 6.0 5.9 3.8 12.7 3.4 10.8 5.1 9.4 0.0 24.7 11.4 13.6 7.3 20.2 5.0 3.7 4.1 12.2 10.3 2.2 2.8 10.5 1.8 1.9 6.9 11.0 18.6 5.5 3.8 11.9 1.0 4.1 9.6 24.5 1.6 10.9 3.0 9.4 0.0 13.6 10.8 1.7 4.1 3.7 12.6 1.4 11.1 33.2 5.3 14.8 B3GAT3 GlcAT-I ENSG00000149541 "Beta-1,3-glucuronyltransferase 3" O94766 11 62615296-62622154 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051328 Approved "Intracellular and membrane" NA NA 990000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA051328: AB_2681444" "unprognostic (1.55e-1)" "unprognostic (3.93e-2)" "unprognostic (8.45e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (4.69e-4)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.11e-6)" "unprognostic (4.94e-2)" "unprognostic (2.42e-1)" "unprognostic (3.66e-2)" "unprognostic (1.08e-3)" "unprognostic (1.40e-1)" "unprognostic (1.58e-3)" "unprognostic (1.46e-3)" "unprognostic (6.00e-2)" "unprognostic (4.48e-2)" "unprognostic (2.58e-2)" 28.2 30.0 63.4 17.0 63.8 18.2 27.4 67.0 81.8 33.7 65.9 27.8 17.2 30.0 11.5 21.0 30.0 15.3 23.1 64.0 66.7 52.1 48.7 29.0 26.2 72.3 64.3 32.3 30.7 19.1 55.7 19.1 76.5 37.1 6.9 16.0 25.9 18.2 14.3 33.9 27.8 14.0 63.3 40.0 28.9 23.9 67.1 18.5 30.1 6.8 10.8 30.5 25.7 69.7 36.0 57.3 32.0 55.0 40.0 38.7 23.4 28.3 38.9 26.7 29.4 25.4 52.3 33.4 91.1 29.5 70.6 24.5 30.8 28.7 6.2 71.5 61.3 17.0 25.9 32.8 96.8 21.4 34.8 69.1 47.6 35.0 15.3 42.4 25.3 37.9 51.5 76.7 33.9 89.1 38.1 76.7 47.5 18.9 55.1 36.7 22.5 175.4 55.0 7.2 33.6 53.1 32.6 38.2 134.6 10.6 52.9 41.6 18.6 28.6 20.8 75.2 54.4 79.3 28.7 37.6 82.3 41.0 56.0 32.0 29.3 27.4 21.6 31.8 14.0 18.5 14.9 17.7 25.8 15.3 14.8 17.2 8.6 41.0 33.8 15.5 19.9 16.4 63.4 63.8 67.0 81.8 64.0 66.7 72.3 64.3 76.5 63.3 67.1 69.7 33.2 6.4 13.2 22.2 36.8 19.8 39.0 53.3 51.2 52.3 33.1 44.4 4.2 31.5 26.1 40.5 33.3 77.0 45.3 26.5 15.6 33.8 0.4 20.0 36.3 22.8 25.2 24.4 19.1 46.3 61.3 34.8 25.5 24.1 1.3 45.3 23.2 28.4 67.8 48.8 25.3 23.9 57.0 35.2 17.5 3.2 36.1 34.4 44.4 8.4 45.3 52.5 49.4 14.6 19.5 36.4 31.2 22.6 51.0 30.6 27.3 16.2 15.2 49.6 26.3 22.3 33.7 6.8 25.8 21.9 19.5 43.5 41.7 31.9 28.3 21.0 B3GLCT "B3GALTL, B3Glc-T, B3GTL" ENSG00000187676 "Beta 3-glucosyltransferase" Q6Y288 13 31199975-31332276 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 59.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (3.31e-2)" "unprognostic (2.53e-1)" "unprognostic (4.71e-2)" "unprognostic (6.17e-3)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" "unprognostic (2.02e-1)" "unprognostic (1.43e-1)" "unprognostic (1.00e-1)" "unprognostic (2.91e-1)" "unprognostic (3.28e-3)" "unprognostic (6.74e-2)" "unprognostic (5.51e-3)" "unprognostic (2.26e-1)" "unprognostic (5.70e-2)" "unprognostic (3.81e-2)" "unprognostic (1.51e-1)" 3.7 2.0 8.6 3.1 11.4 3.9 4.6 6.2 7.8 3.5 12.8 3.1 2.8 12.9 3.9 3.0 6.0 3.5 18.2 8.2 6.9 6.6 3.4 3.7 3.8 6.9 11.2 4.8 3.1 8.1 3.0 7.0 7.1 3.5 3.3 8.0 3.8 6.2 4.7 3.4 2.9 12.7 8.0 3.5 3.4 3.8 13.2 4.9 4.9 2.8 5.6 2.5 3.5 8.0 4.8 6.7 27.1 4.9 5.1 5.1 4.4 11.6 13.0 13.9 9.8 3.5 13.2 19.4 8.3 13.6 26.2 7.9 6.1 7.5 12.9 59.8 11.7 1.3 5.9 5.1 3.2 7.8 10.1 5.9 8.4 8.0 6.8 14.2 12.5 9.5 3.5 3.0 11.0 6.1 11.7 2.4 7.9 7.0 4.1 10.4 8.8 0.6 6.2 6.7 2.5 11.0 10.0 4.7 13.2 6.3 2.3 8.9 17.6 14.0 9.4 6.5 11.7 2.4 5.6 7.3 4.5 5.8 18.9 1.7 0.4 1.3 2.4 0.4 3.5 1.3 1.5 2.7 0.4 0.6 1.2 1.6 0.2 1.4 0.4 0.4 0.9 1.4 8.6 11.4 6.2 7.8 8.2 6.9 6.9 11.2 7.1 8.0 13.2 8.0 4.5 0.0 3.1 0.0 6.6 0.0 3.6 0.0 14.2 10.6 5.1 3.4 23.7 2.8 0.6 9.2 16.7 0.3 7.9 2.5 1.9 4.3 12.1 9.2 5.3 6.5 1.2 1.7 0.0 4.6 2.1 9.0 5.6 4.2 0.0 3.3 8.9 5.5 3.6 0.0 0.0 1.5 0.0 3.2 0.0 2.5 1.5 3.3 0.0 0.0 0.9 5.8 6.2 0.0 0.0 5.6 2.3 3.4 6.4 2.3 2.6 2.6 1.5 4.3 13.1 4.1 5.2 2.1 13.5 7.7 0.0 0.3 6.5 2.3 1.7 1.6 B3GNT10 ENSG00000214654 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 10 (putative)" A8MXE2 9 120792403-120799918 "Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.7;Distal tubular cells: 1.9;Endometrial ciliated cells: 1.5;Endometrial stromal cells: 1.3;Proximal tubular cells: 1.3;Respiratory ciliated cells: 1.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" "unprognostic (4.59e-3)" "unprognostic (2.71e-2)" "unprognostic (3.04e-2)" "unprognostic (5.71e-3)" "unprognostic (1.20e-1)" "unprognostic (3.95e-1)" "unprognostic (7.99e-4)" "unprognostic (1.21e-1)" "unprognostic (2.42e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-1)" "unprognostic (2.57e-2)" "unprognostic (1.08e-7)" "unprognostic (1.91e-2)" "unprognostic (1.79e-1)" "unprognostic (2.28e-1)" "unprognostic (1.73e-1)" 1.2 1.2 0.7 1.8 1.3 4.8 2.1 0.9 0.7 1.3 1.4 1.8 1.5 0.8 2.0 1.2 1.9 1.2 1.1 0.7 0.8 2.7 1.2 1.1 2.7 1.2 0.8 1.7 1.4 2.2 0.8 1.2 1.1 1.9 2.2 2.4 1.3 1.5 1.0 1.2 1.5 0.9 1.0 1.9 2.3 2.4 1.2 2.1 2.8 0.4 2.9 1.2 0.5 2.7 3.0 3.7 4.0 2.6 3.4 2.6 4.9 2.8 2.9 4.7 2.8 1.2 4.5 5.7 2.4 1.4 5.5 7.8 7.1 5.7 5.4 7.0 2.2 3.3 2.7 1.9 5.7 3.9 1.4 2.8 2.9 3.5 8.2 1.0 0.9 6.5 10.2 7.7 2.9 4.3 2.9 0.9 5.8 6.4 3.6 3.0 7.6 8.8 2.6 2.9 5.7 4.4 5.2 2.5 5.5 2.5 10.1 0.8 1.4 2.3 2.0 5.0 2.8 9.1 14.8 5.4 4.9 2.2 4.8 0.3 0.5 1.2 0.9 0.5 1.0 0.8 0.9 1.1 0.6 0.8 1.3 0.7 0.4 1.1 1.0 0.4 1.2 0.7 0.7 1.3 0.9 0.7 0.7 0.8 1.2 0.8 1.1 1.0 1.2 2.7 0.3 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.0 0.0 3.7 0.0 0.0 0.6 0.0 1.9 0.5 0.0 1.5 1.3 0.1 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.3 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 B3GNT3 "B3GN-T3, B3GNT-3, beta3Gn-T3, HP10328, TMEM3" ENSG00000179913 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3" Q9Y2A9 19 17794828-17813576 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.0;salivary gland: 31.4;stomach 1: 43.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 65.8;Cytotrophoblasts: 78.9;Distal enterocytes: 108.4;Paneth cells: 67.4;Proximal enterocytes: 50.5;Syncytiotrophoblasts: 68.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 44.2;BEWO: 40.9;CAPAN-2: 112.5;OE19: 102.1;RT4: 41.3;SK-BR-3: 38.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024298 Enhanced "Intracellular and membrane" NA NA 74000 "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA024298: AB_1845236" "unprognostic (1.10e-1)" "unprognostic (5.19e-2)" "unprognostic (1.84e-1)" "unprognostic (4.84e-3)" "unprognostic (1.10e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (3.26e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.91e-1)" "unprognostic (1.44e-2)" "unprognostic (7.38e-2)" "unprognostic (1.26e-1)" "unprognostic (7.10e-2)" "unprognostic (2.57e-2)" 0.3 0.1 0.3 5.7 0.1 0.2 3.4 0.7 0.4 4.4 0.3 44.0 32.6 0.4 0.0 21.7 1.0 23.8 0.0 0.3 0.3 3.8 2.4 0.5 0.5 0.3 0.2 0.1 3.9 0.5 0.0 12.6 0.3 2.2 40.5 0.0 31.4 3.2 0.0 2.7 29.5 1.7 0.0 0.1 43.2 0.1 0.1 0.2 0.3 0.0 4.7 18.5 8.1 0.5 44.2 12.5 0.0 0.2 0.0 0.0 40.9 0.0 0.0 0.0 0.0 0.7 112.5 0.0 28.9 0.0 0.1 4.2 0.0 12.9 0.0 0.0 0.2 0.0 0.2 5.6 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.2 0.1 0.4 102.1 19.2 0.2 0.0 1.2 23.9 41.3 0.0 0.1 0.0 38.4 0.0 0.0 1.7 0.2 0.1 0.3 3.3 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.7 0.4 0.3 0.3 0.3 0.2 0.3 0.0 0.1 0.5 0.1 0.0 2.3 0.0 0.2 0.1 3.6 5.1 0.0 0.0 7.1 6.2 0.4 65.8 17.1 16.5 0.0 78.9 0.5 108.4 1.9 17.9 0.0 3.8 0.8 2.3 16.3 0.0 0.1 28.4 7.5 0.7 19.9 7.7 5.7 0.0 0.7 0.2 6.0 0.0 0.2 40.7 6.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 33.2 67.4 0.0 0.0 7.8 50.5 3.5 7.7 0.0 0.0 0.0 0.9 0.2 0.3 0.2 0.0 68.3 0.2 0.5 28.4 39.6 B3GNT4 "B3GN-T4, beta3Gn-T4" ENSG00000176383 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4" Q9C0J1 12 122203681-122208952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;skin 1: 3.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 3.3;Excitatory neurons: 3.2;Proximal tubular cells: 9.7;Spermatogonia: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 5.1;hTCEpi: 4.0;T-47d: 4.2;U-266/84: 3.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055261 Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoli "HPA055261: AB_2682765" "unprognostic (1.67e-1)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.60e-2)" "unprognostic (1.32e-3)" "unprognostic (1.98e-1)" "unprognostic (3.44e-2)" "unprognostic (1.21e-1)" "unprognostic (3.82e-2)" "unprognostic (3.69e-1)" "prognostic unfavorable (3.52e-6)" "unprognostic (1.24e-1)" "unprognostic (2.79e-1)" "unprognostic (8.97e-2)" "unprognostic (9.47e-2)" 0.2 0.7 2.3 0.1 2.6 1.5 0.2 4.9 3.1 0.3 0.0 0.3 0.2 0.1 0.0 1.3 0.6 0.2 0.1 3.8 0.5 2.7 0.4 0.3 0.1 0.0 0.0 0.2 0.3 0.3 1.4 0.1 0.0 0.4 0.0 0.5 0.5 0.0 0.2 3.1 0.3 0.0 0.0 0.5 0.3 1.6 0.9 0.0 0.4 0.0 0.1 0.1 0.5 1.2 3.4 0.6 0.2 1.4 0.1 0.1 0.6 0.1 0.0 0.2 0.3 2.2 0.3 0.3 0.5 0.0 0.2 1.3 1.7 1.2 0.1 5.1 1.9 0.1 1.3 0.2 0.4 0.5 0.7 0.3 4.0 0.1 0.2 0.5 0.0 1.3 1.0 0.4 0.0 3.2 0.0 0.5 0.4 0.1 1.4 0.2 0.4 0.7 0.5 0.4 0.8 1.1 0.9 0.7 0.4 0.5 4.2 0.1 0.1 0.3 1.7 0.4 0.2 0.4 3.6 0.8 0.3 0.5 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 2.3 2.6 4.9 3.1 3.8 0.5 0.0 0.0 0.0 0.0 0.9 1.2 0.4 0.0 1.8 0.7 0.3 1.3 0.7 3.3 0.6 0.2 0.7 0.8 0.5 0.0 1.1 0.0 0.0 0.5 0.5 0.6 1.9 1.0 0.4 0.6 0.3 0.3 0.0 0.0 3.2 0.2 1.1 0.3 0.0 0.8 0.0 0.1 0.4 0.0 0.2 0.0 1.4 0.0 2.0 0.6 0.6 0.1 0.3 0.3 0.0 1.9 0.0 0.2 0.0 0.5 0.6 0.4 1.3 0.0 0.4 0.3 0.1 9.7 1.1 0.2 0.0 0.5 0.2 0.8 2.9 0.8 1.4 0.5 0.4 0.1 0.3 0.4 B3GNT5 "B3GN-T5, beta3Gn-T5" ENSG00000176597 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" Q9BYG0 3 183253253-183298504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.5" "Cell type enhanced" "Detected in many" "Adipocytes: 151.2;Distal enterocytes: 150.4;Squamous epithelial cells: 169.9;Syncytiotrophoblasts: 157.9;Urothelial cells: 144.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 5.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 5.6" "Cell line enhanced" "Detected in many" "GAMG: 82.4;HBEC3-KT: 70.3;hTCEpi: 83.5" "Region enriched" "Detected in many" 4 "cerebellum: 14.7" "Low region specificity" "Detected in all" HPA017292 Uncertain Approved Nucleoli NA NA 28000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "HPA017292: AB_1845237" "unprognostic (2.17e-1)" "unprognostic (5.73e-2)" "unprognostic (1.07e-2)" "unprognostic (4.83e-3)" "unprognostic (1.89e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (7.10e-3)" "unprognostic (7.78e-2)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.23e-6)" "unprognostic (4.20e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (3.53e-2)" "unprognostic (8.10e-3)" 11.9 2.4 3.3 13.7 3.5 76.5 5.5 2.3 3.2 6.0 0.9 22.6 38.2 5.1 9.1 37.5 9.6 21.3 3.5 3.7 4.0 3.8 3.3 15.0 1.1 5.6 3.8 4.6 7.5 3.5 5.7 13.9 4.6 7.9 19.6 1.2 10.1 3.3 7.4 10.3 42.0 6.7 4.3 1.6 11.3 7.3 3.5 7.6 5.2 4.5 5.3 24.2 13.8 5.5 46.2 4.4 23.8 14.7 19.5 57.0 21.5 0.7 1.1 4.6 3.8 9.0 23.6 0.0 2.7 0.1 82.4 20.6 24.7 70.3 3.9 0.1 15.3 2.4 1.9 0.0 24.8 23.4 10.9 27.0 83.5 3.7 62.1 6.2 43.4 0.1 26.6 0.1 38.1 0.0 0.1 7.6 10.1 26.9 38.5 7.3 12.0 0.1 14.4 12.7 1.0 22.6 12.7 0.1 5.3 10.6 0.0 28.0 64.6 1.1 9.0 1.4 11.0 0.0 0.0 0.0 8.8 54.1 23.8 0.0 1.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.2 0.3 3.3 3.5 2.3 3.2 3.7 4.0 5.6 3.8 4.6 4.3 3.5 5.5 151.2 6.4 17.5 2.3 1.2 65.1 70.2 35.8 101.3 10.0 18.4 10.4 2.2 21.5 40.5 5.5 22.9 31.0 1.9 150.4 1.9 18.0 13.4 58.0 13.1 26.3 38.2 6.3 1.8 11.8 10.7 9.2 70.3 55.3 14.0 2.4 2.2 0.6 29.6 3.3 1.5 88.2 34.6 15.6 123.2 26.5 1.5 76.8 12.4 80.6 9.4 3.1 0.0 4.5 0.8 35.7 126.4 0.4 1.4 43.1 74.9 4.8 118.5 13.1 0.0 23.6 5.4 7.9 0.8 169.9 84.8 157.9 4.3 0.2 36.2 144.4 B3GNT6 B3Gn-T6 ENSG00000198488 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6" Q6ZMB0 11 77034398-77041973 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 21.8;salivary gland: 6.4;stomach 1: 24.9" "Group enriched" "Detected in some" 20 "Gastric mucus-secreting cells: 23.0;Intestinal goblet cells: 60.8" "Group enriched" "Detected in some" 14 "colorectal cancer: 6.3;lung cancer: 3.9;pancreatic cancer: 5.1;prostate cancer: 5.0;stomach cancer: 4.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039805 Enhanced "Intracellular and membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA039805: AB_2676690" "unprognostic (1.71e-1)" "prognostic favorable (2.31e-4)" "unprognostic (4.79e-2)" "unprognostic (5.42e-2)" "unprognostic (7.64e-2)" "unprognostic (1.95e-1)" "unprognostic (2.72e-1)" "unprognostic (1.23e-2)" "unprognostic (7.77e-2)" "unprognostic (2.19e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-1)" 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 21.8 5.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 16.8 0.0 6.4 0.0 0.0 0.0 7.0 0.3 0.0 0.0 24.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.5 0.0 0.1 0.0 0.6 0.2 0.0 0.0 0.1 0.1 0.4 0.0 1.0 0.0 0.0 0.0 1.4 2.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.2 23.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 60.8 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.6 1.4 0.0 0.0 0.3 1.2 0.1 0.2 0.0 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.5 0.2 B3GNT7 beta3GnT7 ENSG00000156966 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7" Q8NFL0 2 231395710-231401164 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 71.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 272.8;Intestinal goblet cells: 145.2;Paneth cells: 126.4;Undifferentiated cells: 354.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 32.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 19.5;HEL: 15.6;THP-1: 14.0;WM-115: 23.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA013881, HPA035625, HPA035626" Enhanced Approved "Golgi apparatus,Mitotic spindle,Cytosol" "Intracellular and membrane" Yes NA 3600000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Mitotic spindle, Cytosol" "HPA013881: , HPA035625: AB_10601118, HPA035626: AB_2674707" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-3)" "unprognostic (1.46e-2)" "unprognostic (1.28e-2)" "unprognostic (2.69e-1)" "unprognostic (1.36e-1)" "unprognostic (2.31e-2)" "unprognostic (6.18e-2)" "unprognostic (5.82e-2)" "unprognostic (2.17e-2)" "unprognostic (7.77e-2)" "unprognostic (4.27e-3)" "unprognostic (6.96e-2)" "unprognostic (1.18e-1)" "prognostic favorable (6.00e-4)" "unprognostic (3.57e-1)" 3.1 12.9 5.9 2.8 5.1 14.2 3.8 4.0 5.8 2.5 4.6 56.2 25.2 1.9 6.8 2.9 4.6 14.0 4.7 5.6 6.5 2.2 1.2 15.3 1.6 6.0 7.0 16.7 25.4 14.3 8.8 5.4 5.3 3.2 71.2 2.1 7.5 4.4 0.4 5.0 28.4 2.3 4.3 5.1 35.6 1.3 7.3 2.4 8.4 0.3 1.5 3.7 0.6 5.4 0.7 2.8 0.3 0.6 0.1 0.2 1.0 0.2 1.1 0.1 0.1 1.4 19.5 2.2 5.8 0.3 0.2 5.1 0.2 0.0 0.1 0.3 0.5 15.6 0.5 0.9 0.1 0.1 0.8 0.1 1.4 0.2 0.3 1.1 0.2 0.4 0.5 0.4 0.1 0.9 0.2 0.7 6.3 7.7 3.3 0.3 0.1 0.4 0.6 1.7 0.5 0.8 0.3 1.7 0.7 6.9 0.6 14.0 0.2 0.4 0.4 0.2 0.2 2.3 0.9 0.7 0.3 0.2 23.7 0.7 0.1 0.7 2.9 0.5 0.5 9.9 0.1 0.4 6.5 7.0 0.1 0.7 0.2 32.1 0.6 3.1 0.2 1.0 5.9 5.1 4.0 5.8 5.6 6.5 6.0 7.0 5.3 4.3 7.3 5.4 0.9 41.7 30.2 0.3 8.7 2.3 1.7 8.7 0.0 0.4 5.2 2.5 1.1 95.8 29.7 1.8 2.1 0.6 61.7 272.8 0.0 16.1 0.4 13.3 2.2 4.7 103.0 0.4 0.5 84.3 64.9 2.3 51.5 18.5 9.5 17.3 3.3 0.2 11.2 0.0 0.4 145.2 18.3 10.1 38.6 1.2 1.5 9.7 3.6 0.0 2.9 0.5 10.3 55.3 0.2 69.8 126.4 8.2 5.5 11.6 93.2 0.4 82.2 1.8 0.0 0.5 2.3 0.9 1.4 0.0 2.7 2.1 10.0 0.4 354.6 16.2 B3GNT8 "B3GALT7, beta3Gn-T8, BGALT15" ENSG00000177191 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8" Q7Z7M8 19 41425359-41428730 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.5;vagina: 19.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 37.2;Distal enterocytes: 58.1;Ionocytes: 44.7;Paneth cells: 45.0;Proximal enterocytes: 68.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 4 "basophil: 95.0;eosinophil: 117.5;neutrophil: 159.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 159.0" "Cell line enhanced" "Detected in some" "HMC-1: 6.5;HUVEC TERT2: 3.5;K-562: 3.1;THP-1: 3.4;U-937: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043669 Enhanced "Intracellular and membrane" NA NA 57000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "HPA043669: AB_2678608" "unprognostic (6.89e-2)" "unprognostic (2.46e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (4.11e-4)" "unprognostic (6.44e-3)" "unprognostic (6.51e-3)" "unprognostic (1.84e-2)" "unprognostic (9.92e-3)" "unprognostic (7.30e-2)" "unprognostic (2.56e-2)" "prognostic favorable (9.31e-6)" "unprognostic (5.04e-2)" "unprognostic (2.62e-3)" "unprognostic (2.07e-1)" "unprognostic (6.16e-2)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" 2.3 1.2 0.2 1.6 0.4 3.9 2.0 1.1 0.4 11.1 0.2 10.5 15.5 2.4 0.3 44.5 1.8 0.5 6.4 0.1 0.2 3.9 0.5 9.0 0.7 0.5 0.2 0.8 1.5 0.5 1.9 0.5 0.6 3.3 2.7 0.1 6.3 2.6 0.8 5.3 15.3 0.8 0.0 8.6 2.0 0.2 0.3 0.3 1.2 0.9 1.6 2.7 19.5 0.7 0.2 0.0 0.2 0.0 0.3 1.4 0.3 0.4 0.1 0.0 0.0 2.1 0.0 0.1 0.5 1.0 0.0 1.4 0.0 0.3 0.0 0.1 0.2 0.0 0.1 1.1 0.5 0.5 6.5 1.7 1.2 0.0 0.0 0.0 3.5 0.1 3.1 0.2 0.0 0.5 0.0 2.0 0.5 0.0 0.0 0.1 0.4 0.0 0.1 0.7 0.9 0.6 0.0 0.1 0.0 0.2 0.0 3.4 1.3 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.1 5.5 0.0 95.0 16.3 117.5 2.4 12.3 28.4 0.0 1.2 5.2 6.0 0.0 0.1 0.6 159.0 1.5 26.5 0.5 0.6 7.1 0.2 0.4 1.1 0.4 0.1 0.2 0.5 0.2 0.6 0.0 0.3 0.7 0.9 6.4 37.2 0.0 0.0 1.8 5.2 16.3 2.2 0.4 1.4 2.2 0.5 0.0 10.6 23.9 0.0 0.9 0.3 58.1 3.9 5.8 0.0 0.8 0.5 1.7 15.0 1.3 0.1 0.6 2.1 3.0 0.5 1.8 5.1 0.1 2.5 0.0 11.2 0.0 0.1 23.8 44.7 8.8 0.6 0.0 1.5 5.6 0.0 0.0 3.8 0.1 1.0 0.0 0.1 2.9 45.0 0.7 0.1 7.4 68.7 0.3 3.5 0.4 0.0 0.6 2.7 0.0 0.1 20.5 1.7 2.3 1.2 0.0 18.5 13.4 B3GNT9 MGC4655 ENSG00000237172 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9" Q6UX72 16 67148104-67150998 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 12.9;Leydig cells: 11.5;Peritubular cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SiHa: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052743, HPA062734" Approved Approved "Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoli fibrillar center" "HPA052743: AB_2681934, HPA062734: AB_2684854" "unprognostic (2.56e-2)" "unprognostic (2.22e-1)" "unprognostic (2.34e-2)" "unprognostic (1.07e-1)" "unprognostic (6.58e-2)" "unprognostic (1.11e-1)" "unprognostic (1.32e-3)" "unprognostic (3.28e-2)" "unprognostic (3.01e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "unprognostic (2.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.51e-2)" "unprognostic (1.15e-1)" "unprognostic (4.96e-3)" "unprognostic (7.56e-3)" 7.7 8.4 7.1 4.2 8.0 0.2 5.7 7.5 6.8 15.0 8.4 7.6 3.2 13.4 7.3 5.2 13.7 6.8 13.8 7.1 8.0 7.4 2.5 9.0 2.9 8.7 9.7 15.0 3.5 21.8 20.5 7.9 8.7 11.8 3.3 1.4 9.0 14.8 1.9 5.9 5.6 7.8 9.3 5.6 6.1 6.0 7.7 1.5 18.7 2.1 2.5 11.7 8.9 11.1 4.9 8.8 0.7 0.9 27.7 28.6 1.0 22.5 36.2 14.4 18.5 4.0 0.8 0.6 1.5 34.9 6.0 11.1 0.3 1.0 7.8 7.6 3.2 0.7 9.7 3.5 22.3 0.6 0.5 23.7 8.3 14.0 0.4 35.8 2.0 0.5 1.0 2.7 22.6 2.6 2.6 1.2 5.4 3.8 7.7 7.4 12.9 4.4 2.3 6.0 5.0 11.2 50.9 0.2 0.8 4.3 1.3 3.9 4.6 25.6 1.1 25.9 10.2 3.2 2.4 0.8 31.9 1.3 12.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 7.1 8.0 7.5 6.8 7.1 8.0 8.7 9.7 8.7 9.3 7.7 11.1 1.2 6.4 5.0 1.0 1.2 3.2 2.8 2.4 9.6 1.6 3.2 2.3 2.6 5.7 2.4 3.7 0.0 0.3 0.1 0.4 0.0 1.3 5.3 2.5 7.6 2.0 2.4 0.0 0.4 1.7 0.5 12.9 2.6 2.2 0.0 3.0 6.4 0.1 1.8 0.0 1.3 0.9 2.0 0.6 3.3 6.9 11.5 0.4 1.8 0.0 0.1 0.9 0.0 1.0 2.3 0.9 0.1 13.5 4.7 2.4 0.1 0.9 4.2 0.3 6.6 3.2 6.6 4.4 2.8 2.7 4.1 0.8 1.5 2.9 0.8 1.3 B4GALNT1 "beta1-4GalNAc-T, GALGT, SPG26" ENSG00000135454 "Beta-1,4-N-acetyl-galactosaminyltransferase 1" Q00973 12 57623409-57633239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 61.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.0;Excitatory neurons: 22.0;Horizontal cells: 21.9;Inhibitory neurons: 13.4;Smooth muscle cells: 7.5" "Cancer enriched" "Detected in many" 6 "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 67.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008968 Enhanced "Intracellular and membrane" NA NA 35000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA008968: AB_1078253" "unprognostic (3.18e-1)" "unprognostic (8.34e-2)" "unprognostic (2.05e-2)" "unprognostic (3.33e-3)" "unprognostic (2.54e-1)" "unprognostic (2.70e-3)" "unprognostic (3.73e-5)" "unprognostic (1.26e-2)" "unprognostic (1.72e-1)" "unprognostic (2.66e-1)" "unprognostic (2.00e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.18e-14)" "unprognostic (2.52e-2)" "unprognostic (1.81e-1)" "unprognostic (1.44e-2)" "unprognostic (4.92e-4)" 1.9 1.1 26.9 1.9 29.7 0.0 0.7 29.3 61.1 1.3 0.6 2.7 0.5 2.1 2.7 0.7 0.7 1.1 3.3 34.9 21.9 0.8 0.4 0.6 0.6 16.7 11.8 0.3 0.3 0.3 1.7 0.4 20.5 2.6 1.2 4.2 1.8 5.0 9.5 0.6 1.2 2.5 8.1 0.6 0.9 0.7 19.1 0.3 1.2 7.2 1.0 1.2 1.6 29.9 7.5 38.2 18.2 38.7 0.3 0.1 0.4 3.0 11.3 19.0 17.5 2.8 21.9 3.0 47.9 13.2 35.9 3.3 15.3 2.1 5.2 67.4 2.6 1.8 10.1 9.9 0.4 3.1 4.1 0.1 0.9 11.0 0.5 6.7 0.2 11.4 8.7 34.8 2.4 13.5 2.5 0.1 13.0 0.9 7.7 0.1 27.1 8.0 0.1 0.1 34.9 12.3 3.1 1.1 0.4 0.9 7.0 3.3 0.0 22.8 28.1 24.0 26.1 37.0 34.0 2.6 28.9 2.3 45.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 26.9 29.7 29.3 61.1 34.9 21.9 16.7 11.8 20.5 8.1 19.1 29.9 0.8 0.0 0.0 2.6 0.0 0.4 0.0 0.0 0.0 10.0 0.0 0.5 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.0 0.8 0.0 0.0 22.0 0.2 0.2 1.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 21.9 13.4 0.0 0.0 0.0 0.3 0.7 2.8 0.1 3.6 2.8 2.6 0.7 0.0 4.5 2.7 0.5 0.0 3.0 0.0 0.1 0.0 0.2 0.0 2.6 6.6 0.6 7.5 1.6 4.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 B4GALNT3 "B4GalNac-T3, FLJ16224, FLJ40362" ENSG00000139044 "Beta-1,4-N-acetyl-galactosaminyltransferase 3" Q6L9W6 12 459939-563509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 61.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 81.1;Gastric mucus-secreting cells: 128.0;Glandular and luminal cells: 47.4;Late spermatids: 89.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 33.5;HDLM-2: 13.2;HEK 293: 12.5;NTERA-2: 14.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA011404 Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" Vesicles "HPA011404: AB_1845242" "unprognostic (2.38e-2)" "unprognostic (9.59e-3)" "unprognostic (1.38e-1)" "prognostic favorable (1.69e-10)" "unprognostic (4.22e-2)" "unprognostic (4.63e-2)" "unprognostic (1.46e-2)" "unprognostic (9.53e-3)" "unprognostic (3.29e-1)" "unprognostic (1.61e-1)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (9.99e-3)" "unprognostic (2.82e-1)" "unprognostic (2.48e-2)" "unprognostic (2.98e-1)" 0.2 7.0 0.5 3.2 0.7 2.1 1.3 0.0 1.0 7.4 1.0 18.4 1.0 6.2 2.7 7.5 3.7 2.2 23.9 0.5 0.0 4.6 0.1 5.2 0.1 0.0 0.0 0.4 2.6 16.9 9.3 0.1 0.0 2.0 12.5 0.1 4.8 0.7 1.5 14.8 2.0 2.2 0.0 0.3 61.0 8.0 0.0 2.3 2.3 0.1 0.7 1.4 5.6 0.7 0.0 0.0 0.3 1.2 0.0 0.0 33.5 0.0 0.0 0.0 0.0 8.0 6.6 0.0 0.9 0.0 0.7 3.6 8.0 1.1 0.1 13.2 12.5 0.0 0.0 1.8 0.0 0.1 5.3 0.0 5.3 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.4 0.0 0.1 14.8 10.5 0.6 0.5 5.0 0.0 7.1 6.8 3.8 2.7 0.8 0.3 1.0 4.9 0.8 2.9 0.0 0.0 2.7 0.2 0.9 0.0 0.0 0.0 0.0 9.2 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 7.0 1.3 0.3 7.5 6.0 3.4 0.0 0.6 2.9 0.6 15.1 1.5 6.2 9.2 0.0 0.0 0.6 81.1 0.0 12.0 26.3 20.4 4.8 0.6 10.3 0.0 32.6 4.8 0.1 1.6 128.0 47.4 0.0 0.1 0.0 0.1 0.7 0.0 5.2 18.6 2.0 0.0 1.1 89.2 0.0 0.5 0.0 2.8 0.6 0.0 0.0 1.0 3.6 16.6 33.4 0.0 0.2 12.7 1.9 0.2 9.1 0.2 0.0 0.2 0.8 2.8 1.3 0.9 17.3 0.0 1.5 1.9 26.1 14.4 B4GALNT4 "FLJ25045, NGalNAc-T1" ENSG00000182272 "Beta-1,4-N-acetyl-galactosaminyltransferase 4" Q76KP1 11 369499-382117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3;ovary: 27.8" "Cell type enhanced" "Detected in many" "Astrocytes: 133.2;Bipolar cells: 23.8;Excitatory neurons: 31.2;Horizontal cells: 33.7;Inhibitory neurons: 32.3;Muller glia cells: 45.6;Oligodendrocyte precursor cells: 28.1;Oligodendrocytes: 32.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 35.4;NTERA-2: 32.0;SCLC-21H: 39.5;SH-SY5Y: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043276, HPA053126" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA No "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cytosol" Vesicles "HPA043276: , HPA053126: AB_2682049" "unprognostic (6.11e-2)" "unprognostic (7.82e-2)" "unprognostic (1.79e-1)" "unprognostic (6.92e-3)" "unprognostic (5.36e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-1)" "unprognostic (1.53e-1)" "unprognostic (1.69e-3)" "unprognostic (4.99e-3)" "unprognostic (1.52e-10)" "unprognostic (9.01e-2)" "unprognostic (2.56e-1)" "unprognostic (2.92e-4)" "unprognostic (1.25e-1)" 0.9 0.6 23.1 0.9 17.2 0.0 3.3 5.1 33.3 17.2 0.0 5.9 0.6 14.1 0.6 2.3 11.9 0.5 1.6 23.8 12.9 1.0 0.3 0.5 0.3 19.3 20.7 27.8 1.1 2.6 17.9 0.0 14.9 6.3 0.2 5.3 2.0 1.2 0.0 2.1 2.9 1.0 8.4 0.3 2.1 1.5 15.1 0.3 0.5 0.0 0.3 1.8 6.3 13.4 0.0 4.8 35.4 20.4 0.0 0.1 8.4 6.5 1.7 2.9 0.8 3.7 0.0 0.0 4.8 0.7 5.6 1.4 4.8 8.5 0.8 0.0 12.3 0.0 13.4 11.4 0.4 0.0 8.7 0.6 5.0 0.2 3.8 12.7 0.4 1.9 11.5 0.0 0.0 10.8 0.4 0.0 32.0 0.6 14.0 0.0 0.0 4.9 0.4 0.0 39.5 47.6 2.4 1.7 0.5 3.7 14.0 0.0 9.0 2.0 11.1 3.5 0.4 0.1 1.7 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 17.2 5.1 33.3 23.8 12.9 19.3 20.7 14.9 8.4 15.1 13.4 0.1 0.0 0.0 133.2 0.2 0.8 1.5 1.4 0.6 23.8 6.5 8.9 12.5 0.0 0.1 1.8 4.2 0.1 0.3 0.1 0.0 1.3 0.0 0.6 7.1 0.6 1.8 0.0 31.2 0.0 0.0 2.4 0.0 1.1 0.0 6.9 0.0 0.0 0.2 33.7 32.3 0.1 2.0 0.0 0.0 0.0 3.1 0.1 3.6 2.8 0.2 45.6 0.0 28.1 32.5 0.2 0.0 1.2 0.0 2.6 0.0 0.0 0.1 8.6 0.0 0.0 3.3 0.1 0.2 0.1 0.3 0.3 0.1 0.6 0.5 0.4 B4GALT4 beta4Gal-T4 ENSG00000121578 "Beta-1,4-galactosyltransferase 4" O60513 3 119211732-119240946 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 76.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 123.6;Urothelial cells: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 125.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046819, HPA063546" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA046819: AB_2679824, HPA063546: AB_2685036" "unprognostic (4.07e-2)" "unprognostic (1.78e-2)" "unprognostic (3.27e-2)" "unprognostic (1.14e-3)" "unprognostic (4.59e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (6.30e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-1)" "unprognostic (6.10e-3)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" 12.4 9.1 6.8 10.7 8.4 20.1 11.1 6.5 8.1 16.4 8.7 30.6 28.6 14.8 76.0 17.7 21.8 33.2 12.9 7.0 6.9 24.1 16.6 9.9 9.9 6.9 6.7 18.4 19.5 15.1 18.2 25.7 6.9 13.7 35.2 9.9 12.2 14.7 6.3 14.1 32.5 13.6 7.0 9.4 29.3 8.3 7.5 7.4 16.4 6.5 11.5 37.6 10.5 7.2 60.1 100.3 12.8 9.8 36.0 31.1 65.3 125.8 54.4 54.4 56.2 65.4 18.3 11.8 23.9 61.3 32.2 78.6 20.7 15.0 59.9 23.5 6.8 15.1 20.3 31.7 25.3 8.9 15.7 21.2 21.4 23.0 19.3 21.6 5.8 8.0 11.2 11.7 25.5 18.4 5.3 10.7 17.6 34.0 27.2 4.9 11.8 4.7 31.2 60.3 10.9 24.0 29.4 14.6 27.9 28.2 30.2 5.7 4.9 27.3 24.0 15.2 13.5 27.2 21.5 16.1 23.5 10.1 23.5 20.1 4.1 8.3 13.3 5.2 7.3 4.2 7.3 7.9 5.5 3.2 13.6 7.1 2.5 14.8 5.0 3.4 2.7 5.7 6.8 8.4 6.5 8.1 7.0 6.9 6.9 6.7 6.9 7.0 7.5 7.2 8.5 0.0 9.4 7.2 17.1 10.7 22.2 48.9 12.0 10.8 14.9 12.4 9.2 61.5 69.1 7.3 4.2 36.2 46.0 43.2 1.9 30.7 2.1 40.1 16.9 8.4 13.8 7.8 11.9 33.2 123.6 24.0 36.2 74.5 13.3 35.0 3.9 10.8 14.4 18.5 11.1 78.7 16.2 9.8 14.8 2.4 14.9 14.9 14.2 6.5 10.9 22.2 39.1 10.6 10.2 40.5 50.2 28.2 27.4 30.7 59.3 22.6 52.6 10.2 19.7 13.9 16.9 1.7 8.4 14.0 10.5 52.3 23.1 20.0 23.6 171.6 B4GALT5 beta4GalT-V ENSG00000158470 "Beta-1,4-galactosyltransferase 5" O43286 20 49632945-49713878 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077777 Approved Vesicles "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Vesicles "HPA077777: " "unprognostic (7.98e-2)" "unprognostic (5.27e-2)" "unprognostic (2.62e-1)" "unprognostic (1.88e-2)" "unprognostic (2.76e-1)" "unprognostic (1.61e-2)" "prognostic unfavorable (2.69e-5)" "unprognostic (1.73e-1)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "prognostic unfavorable (1.87e-5)" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (3.30e-2)" "unprognostic (5.41e-1)" "unprognostic (2.07e-1)" "unprognostic (2.69e-2)" 28.7 47.8 14.7 21.7 14.5 93.7 18.6 14.6 16.1 21.2 6.5 24.9 25.3 23.5 8.6 37.3 18.5 31.5 20.5 15.5 18.1 22.8 25.8 27.3 9.6 14.7 19.2 19.0 12.6 11.3 12.6 27.2 15.4 17.1 23.7 7.7 19.0 21.9 67.1 7.9 21.3 37.6 14.6 27.6 25.8 22.3 19.0 8.1 11.5 24.3 11.5 51.4 17.2 12.0 48.8 55.0 71.4 30.4 72.8 49.3 62.4 23.5 43.7 104.8 50.0 71.1 59.0 14.8 98.0 39.0 99.1 75.4 45.5 35.0 61.3 45.6 12.5 39.4 28.8 42.9 22.9 51.6 73.7 74.3 32.2 45.5 21.8 96.5 64.8 25.9 64.5 8.9 30.8 24.1 3.1 47.3 37.4 47.8 35.3 26.6 61.9 21.4 50.6 34.0 84.9 43.0 83.6 105.3 47.8 52.5 24.1 70.0 50.1 62.7 50.5 33.6 49.8 10.9 10.0 35.2 32.6 48.5 40.7 1.4 1.0 2.6 1.4 1.0 1.5 0.2 0.6 1.3 0.7 0.3 0.1 0.9 6.6 1.2 1.1 0.6 0.8 0.4 14.7 14.5 14.6 16.1 15.5 18.1 14.7 19.2 15.4 14.6 19.0 12.0 39.5 16.0 43.1 36.2 5.8 18.9 27.3 39.7 7.4 8.3 17.3 18.2 18.3 42.9 84.5 36.8 10.4 23.4 21.3 61.3 1.9 35.3 5.2 59.1 28.4 42.7 34.3 33.2 52.1 19.7 27.7 27.3 17.9 100.8 83.2 36.2 58.5 22.7 24.5 11.8 59.5 21.3 40.7 28.2 81.5 6.8 19.9 45.0 21.4 30.9 21.4 5.6 20.6 25.6 42.5 39.7 34.1 32.7 7.3 66.8 13.4 33.5 57.0 4.9 26.3 29.9 25.9 10.3 16.0 27.5 17.5 5.6 17.4 33.1 20.0 128.9 B4GALT6 beta4GalT-VI ENSG00000118276 "Beta-1,4-galactosyltransferase 6" Q9UBX8 18 31622247-31685836 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 25.3" "Group enriched" "Detected in many" 5 "Bipolar cells: 101.3;Cone photoreceptor cells: 39.6;Excitatory neurons: 71.5;Inhibitory neurons: 103.7;Oligodendrocyte precursor cells: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "REH: 46.8;WM-115: 126.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020701, HPA058284" Approved "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 17: WM-115 - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "CAB020701: , HPA058284: AB_2683668" "unprognostic (3.79e-1)" "unprognostic (4.52e-1)" "unprognostic (6.54e-3)" "unprognostic (2.23e-4)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.31e-2)" "unprognostic (4.50e-2)" "unprognostic (5.18e-1)" "unprognostic (1.13e-1)" "prognostic favorable (5.65e-4)" "unprognostic (2.77e-1)" "prognostic favorable (6.40e-5)" "unprognostic (5.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.10e-2)" "unprognostic (4.00e-1)" 3.8 12.1 2.0 2.7 3.1 4.5 1.3 8.4 10.2 1.1 1.6 3.4 7.2 1.9 2.0 4.5 2.3 6.6 3.6 5.2 4.8 3.2 2.6 1.1 1.4 1.2 2.7 3.8 1.9 7.4 1.8 2.6 2.1 5.1 3.3 25.3 4.5 3.8 3.5 2.1 9.2 1.7 0.9 1.6 3.0 5.2 5.0 6.3 2.0 6.4 1.1 2.4 0.6 0.4 6.0 13.1 23.7 13.4 0.4 0.5 8.7 1.9 0.0 0.4 0.2 25.2 5.0 9.4 10.9 2.3 28.4 2.4 12.7 10.7 1.5 37.1 11.2 12.4 1.3 0.6 2.6 22.6 2.0 2.4 2.3 3.6 7.5 12.0 13.3 21.9 1.8 0.0 0.1 3.6 25.4 1.7 10.2 7.1 7.2 46.8 4.2 0.0 2.9 12.3 12.6 19.7 8.7 1.5 15.7 19.1 1.7 6.8 13.4 26.5 5.5 0.0 14.9 8.9 0.5 19.4 10.8 20.2 126.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 1.2 0.1 0.0 0.0 0.1 2.0 3.1 8.4 10.2 5.2 4.8 1.2 2.7 2.1 0.9 5.0 0.4 3.2 0.0 0.5 12.7 0.0 5.5 0.9 1.5 12.0 101.3 2.0 1.8 7.6 0.0 1.2 1.8 39.6 0.6 5.9 2.6 3.9 1.3 6.1 1.2 6.2 3.6 3.0 4.6 71.5 1.1 0.2 3.0 2.6 1.3 0.0 4.5 4.2 2.1 0.7 13.5 103.7 2.1 0.0 0.6 1.2 3.5 1.2 1.5 0.0 9.4 0.3 4.6 6.2 81.4 5.3 2.3 3.1 2.6 1.1 2.3 5.4 1.2 0.6 5.6 0.0 1.2 1.6 1.0 9.7 3.7 1.7 0.3 1.4 1.4 3.8 0.7 B4GALT7 "beta4Gal-T7, XGALT-1" ENSG00000027847 "Beta-1,4-galactosyltransferase 7" Q9UBV7 5 177600132-177610330 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042330 Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA042330: AB_10796576" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (3.12e-1)" "unprognostic (5.97e-2)" "prognostic unfavorable (2.29e-4)" "unprognostic (9.53e-2)" "unprognostic (4.19e-3)" "unprognostic (3.86e-2)" "unprognostic (1.18e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-3)" "unprognostic (2.00e-2)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (4.44e-2)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" 19.0 43.7 21.1 15.3 20.1 24.8 17.0 20.6 25.5 18.4 21.8 15.1 16.9 20.1 12.5 16.6 16.0 12.5 23.4 20.1 21.8 20.2 30.5 13.4 20.1 24.8 25.1 19.8 37.6 24.3 31.5 14.1 24.8 22.5 11.9 5.9 24.2 18.8 20.2 13.6 14.7 11.8 18.5 21.3 21.8 23.9 22.1 10.6 18.5 10.1 11.8 17.9 13.9 18.7 20.2 34.5 14.2 35.6 28.0 20.7 63.7 30.1 31.9 26.9 30.7 32.6 30.8 25.2 54.7 30.9 47.3 22.9 9.8 64.9 11.7 85.4 25.8 13.3 27.5 23.4 40.0 13.8 22.4 31.8 22.7 29.0 23.5 24.7 30.3 16.9 11.8 23.7 27.4 46.0 11.9 17.1 13.9 17.7 50.0 24.1 10.3 27.8 20.6 29.6 12.5 14.4 15.0 29.8 27.6 11.3 19.4 16.3 23.5 34.0 19.5 22.6 30.6 29.5 14.9 18.4 28.8 33.0 31.8 16.8 16.7 9.7 14.0 19.7 12.6 14.4 12.8 12.2 19.3 18.4 11.4 11.3 1.3 11.1 19.4 15.2 9.2 10.9 21.1 20.1 20.6 25.5 20.1 21.8 24.8 25.1 24.8 18.5 22.1 18.7 16.3 3.2 5.6 5.2 24.5 6.6 15.4 27.8 15.9 12.1 16.5 19.3 6.9 12.8 15.8 16.5 4.2 43.8 16.4 13.8 7.9 34.1 13.9 12.5 17.8 15.6 14.5 8.2 4.3 38.9 132.4 21.2 8.2 13.5 10.2 30.0 10.8 15.9 31.7 11.8 6.0 22.2 8.2 17.8 8.9 9.8 14.0 18.8 21.4 3.7 25.6 13.7 13.4 3.0 3.4 34.0 12.4 18.4 52.8 30.7 17.4 19.6 9.3 16.1 0.0 13.9 16.4 14.3 11.3 13.9 8.8 43.9 12.8 33.4 23.3 16.3 B4GAT1 "B3GN-T1, B3GNT1, B3GNT6, BETA3GNTI, iGAT, iGNT" ENSG00000174684 "Beta-1,4-glucuronyltransferase 1" O43505 11 66345374-66347629 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 220.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.3;Horizontal cells: 158.2;Muller glia cells: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015484 Uncertain "Intracellular and membrane" NA NA 57000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "HPA015484: AB_1845235" "unprognostic (1.80e-1)" "unprognostic (7.20e-2)" "unprognostic (1.70e-1)" "unprognostic (3.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.45e-1)" "unprognostic (9.23e-2)" "unprognostic (1.59e-1)" "unprognostic (2.65e-2)" "unprognostic (3.43e-3)" "prognostic favorable (3.55e-5)" "unprognostic (2.20e-1)" "unprognostic (3.50e-1)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-1)" "unprognostic (2.76e-3)" 16.6 41.4 120.6 6.1 124.9 1.3 16.0 71.0 125.2 23.1 68.7 30.1 16.2 28.5 15.2 8.3 23.4 9.9 44.6 115.3 220.2 25.3 18.8 17.3 6.7 85.9 97.3 34.3 25.5 22.6 62.3 22.5 101.0 17.3 7.7 46.0 15.8 22.4 27.7 12.1 14.6 14.0 91.9 10.2 25.8 8.2 150.4 6.5 21.0 19.2 4.3 20.2 16.3 83.9 10.8 26.7 29.7 36.5 32.6 29.3 39.4 18.4 42.5 28.1 22.9 20.1 14.9 8.9 76.1 16.9 24.1 16.8 32.0 20.6 13.5 17.6 58.2 1.3 20.4 77.6 19.3 7.0 2.7 28.6 15.6 17.5 7.4 92.8 33.5 14.8 8.6 13.7 13.6 18.1 16.7 19.1 20.2 10.6 28.0 24.0 23.2 15.9 29.6 2.7 17.8 33.7 15.8 10.4 74.8 18.4 42.6 6.8 19.7 21.8 15.9 28.0 9.6 26.1 19.2 5.3 36.8 5.8 26.0 0.0 1.2 0.0 7.1 0.4 9.9 5.7 7.8 7.6 3.0 3.2 9.0 8.3 0.4 4.6 0.3 7.4 5.7 4.4 120.6 124.9 71.0 125.2 115.3 220.2 85.9 97.3 101.0 91.9 150.4 83.9 13.5 22.4 10.8 25.8 2.9 0.0 1.6 0.0 14.2 72.3 6.2 12.7 45.9 25.8 1.8 20.2 58.4 57.8 8.6 8.0 5.9 7.4 0.5 3.9 9.7 17.1 4.9 0.8 22.1 6.0 22.6 23.4 6.6 2.6 1.3 22.5 30.4 24.4 12.7 158.2 35.0 8.0 0.0 2.4 0.0 2.4 32.6 2.6 0.0 10.3 1.3 70.1 2.1 22.6 14.2 4.3 4.9 40.6 6.1 2.0 13.3 17.5 2.9 47.4 26.3 21.2 11.8 1.4 2.8 5.8 0.0 18.1 2.6 28.0 7.2 0.3 B9D1 "B9, EPPB9, MKS9, MKSR-1" ENSG00000108641 "B9 domain containing 1" Q9UPM9 17 19334308-19378193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 226.2;Endometrial ciliated cells: 99.7;Late spermatids: 171.8;Respiratory ciliated cells: 159.5;Spermatocytes: 141.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022957 Approved "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "HPA022957: AB_1848220" "unprognostic (3.13e-2)" "unprognostic (3.78e-2)" "unprognostic (2.16e-1)" "unprognostic (3.66e-3)" "unprognostic (9.82e-3)" "unprognostic (1.37e-2)" "unprognostic (6.57e-3)" "unprognostic (1.32e-1)" "unprognostic (1.29e-1)" "unprognostic (1.46e-2)" "unprognostic (1.83e-2)" "unprognostic (2.21e-1)" "prognostic favorable (4.14e-4)" "unprognostic (3.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.23e-1)" "unprognostic (1.18e-3)" 7.7 20.9 20.1 3.9 22.0 5.7 12.2 16.5 23.0 14.3 38.1 10.2 6.0 15.4 54.8 9.3 62.7 11.1 13.5 20.7 19.4 26.0 10.4 9.5 3.8 18.9 20.8 15.7 22.1 34.2 60.9 5.1 15.6 11.3 7.5 21.8 11.4 18.1 5.9 7.1 5.3 11.8 17.0 7.4 10.4 65.3 21.0 3.7 39.4 5.4 4.5 8.1 7.9 17.9 66.7 61.2 14.9 20.9 18.8 29.2 18.6 10.9 55.8 35.4 37.5 14.1 17.6 18.0 13.9 21.3 20.6 27.3 11.2 31.6 22.1 6.2 41.0 1.1 30.8 43.8 30.6 4.3 2.9 23.4 24.4 22.2 42.0 50.3 33.2 21.5 10.5 2.0 33.2 57.6 2.1 5.3 10.7 32.0 21.3 11.6 1.6 29.9 74.9 4.5 43.6 10.8 22.8 5.7 15.5 42.7 47.1 7.2 6.4 9.4 23.2 10.4 11.7 11.6 2.3 5.5 23.0 2.4 15.7 0.0 0.6 0.0 0.7 1.8 0.9 2.2 0.5 0.6 0.2 0.4 0.6 0.4 0.0 0.8 1.6 0.3 0.2 1.0 20.1 22.0 16.5 23.0 20.7 19.4 18.9 20.8 15.6 17.0 21.0 17.9 1.5 16.0 11.9 13.4 8.1 3.8 10.7 23.0 13.1 5.8 10.5 13.6 10.9 8.6 19.9 38.6 12.5 4.4 0.7 2.6 64.6 19.8 226.2 99.7 8.1 4.9 20.4 9.0 14.5 14.6 4.8 14.6 12.2 5.9 0.0 9.5 3.3 4.6 5.4 5.0 10.6 12.8 14.2 1.0 1.7 171.8 13.1 2.3 16.0 1.9 1.3 14.0 1.0 10.1 8.2 9.6 2.9 9.8 27.2 11.1 1.3 82.6 159.5 16.6 6.6 7.3 30.8 141.5 26.8 14.2 2.0 2.6 2.1 25.2 7.3 7.0 BACE2 "AEPLC, ALP56, CEAP1, DRAP" ENSG00000182240 "Beta-secretase 2" Q9Y5Z0 21 41167801-41282530 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 26.8" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 290.4;Syncytiotrophoblasts: 514.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 2.9;eosinophil: 5.2" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.2" "Cell line enhanced" "Detected in many" "OE19: 73.8;SK-BR-3: 53.3;SK-MEL-30: 52.6;WM-115: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035416 Approved "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 17: WM-115 - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA035416: AB_2732467" "unprognostic (1.71e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (5.23e-2)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.86e-4)" "unprognostic (1.52e-2)" "unprognostic (2.58e-2)" "unprognostic (2.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.49e-1)" "unprognostic (3.46e-2)" "unprognostic (8.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.76e-2)" "unprognostic (5.83e-2)" 10.0 1.6 2.1 4.3 3.1 0.6 7.7 4.4 2.6 6.1 9.4 7.3 3.5 8.7 1.9 9.4 6.3 8.3 6.2 2.0 4.1 9.8 1.7 4.3 3.1 6.7 3.8 2.7 13.1 2.3 1.5 2.9 5.1 8.3 4.5 0.3 26.8 2.6 2.2 5.0 4.5 4.7 5.5 4.7 22.9 1.0 4.1 1.1 4.6 2.2 3.6 6.7 5.6 8.7 27.4 2.1 12.6 0.0 2.5 2.1 0.1 6.3 0.0 3.9 3.8 0.0 9.6 0.1 12.2 7.1 7.2 8.1 0.0 13.6 1.4 0.0 12.6 6.2 3.3 0.0 1.0 0.0 14.4 5.5 2.8 0.5 2.7 20.9 12.1 6.4 0.0 0.1 6.0 6.1 3.4 0.0 8.5 73.8 12.1 1.0 0.0 9.8 11.5 2.5 0.4 0.1 0.5 53.3 52.6 1.0 12.0 0.1 15.8 7.3 5.3 6.5 10.9 0.1 0.1 0.0 17.8 0.0 46.2 2.9 0.0 5.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 3.1 4.4 2.6 2.0 4.1 6.7 3.8 5.1 5.5 4.1 8.7 55.0 12.8 15.9 11.8 28.6 18.5 91.6 25.6 42.7 0.8 40.3 33.8 9.7 123.0 72.5 20.2 2.1 127.6 0.5 40.5 93.9 146.3 24.3 65.4 19.8 90.2 18.5 22.1 11.7 105.2 64.2 34.0 186.6 115.8 90.7 6.7 35.3 1.0 28.0 0.0 7.5 86.2 44.7 17.0 8.2 16.0 14.3 3.6 179.7 20.6 2.9 3.1 0.0 9.5 46.0 86.6 23.9 18.8 3.2 290.4 7.3 1.4 76.5 0.8 0.0 15.9 23.6 0.6 1.4 43.5 11.8 514.7 6.2 8.7 56.6 134.2 BAIAP2 "BAP2, IRSp53, WAML" ENSG00000175866 "BAR/IMD domain containing adaptor protein 2" Q9UQB8 17 81035122-81117432 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 185.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 19.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023310, HPA027421" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 18000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA023310: AB_1845264, HPA027421: AB_10602392" "unprognostic (2.20e-1)" "unprognostic (1.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.28e-2)" "unprognostic (1.73e-1)" "unprognostic (6.97e-3)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (6.77e-2)" "unprognostic (1.45e-2)" "unprognostic (4.23e-2)" "unprognostic (2.94e-1)" "unprognostic (7.04e-2)" "unprognostic (6.77e-2)" "unprognostic (7.15e-2)" "unprognostic (1.62e-2)" "prognostic unfavorable (7.58e-6)" 23.9 18.2 129.1 7.4 140.0 2.6 27.1 95.7 176.1 49.9 104.6 44.0 6.7 30.9 46.5 132.9 37.6 29.3 24.2 163.7 103.1 38.0 85.7 49.1 6.9 68.0 81.0 13.7 13.4 19.9 56.3 31.8 68.3 61.3 12.1 16.2 57.5 27.6 13.1 132.4 14.7 19.3 70.5 11.8 62.3 26.3 119.9 11.8 27.1 9.8 25.3 23.3 73.2 121.9 99.9 45.1 28.1 36.6 22.2 29.0 32.8 40.2 26.1 35.7 15.8 60.9 49.1 0.5 28.3 35.8 73.5 93.6 26.1 46.1 13.7 0.4 32.8 20.2 41.3 46.4 20.7 0.0 28.2 12.5 53.0 29.5 15.4 32.7 19.5 1.1 26.4 0.6 20.6 51.2 4.0 22.3 11.8 65.6 38.1 6.0 6.6 81.3 108.5 34.5 36.8 39.9 64.2 91.3 110.1 23.1 80.4 22.6 23.8 81.6 78.4 13.8 43.4 1.4 0.3 1.4 72.0 3.3 18.3 0.0 7.9 0.5 3.2 9.4 1.0 0.1 1.2 1.0 10.3 0.1 1.3 1.8 5.4 1.9 9.2 19.5 0.5 3.2 129.1 140.0 95.7 176.1 163.7 103.1 68.0 81.0 68.3 70.5 119.9 121.9 74.1 76.9 39.0 13.4 6.2 63.7 138.4 42.3 94.4 37.1 49.4 37.1 22.5 25.8 47.2 22.0 79.2 77.1 16.6 18.8 7.9 9.8 10.5 80.8 10.4 35.7 49.3 0.8 65.3 5.1 9.2 28.0 88.2 79.7 13.4 3.1 45.0 78.6 43.2 11.8 13.6 29.1 24.4 18.3 58.2 29.4 6.8 31.2 40.9 13.1 18.6 18.5 0.0 4.5 5.9 14.8 8.0 3.8 3.1 77.0 3.7 25.4 110.8 19.1 0.0 10.4 13.3 7.6 33.0 103.6 75.3 101.0 13.9 8.2 14.7 185.1 BAZ2B WALp4 ENSG00000123636 "Bromodomain adjacent to zinc finger domain 2B" Q9UIF8 2 159318979-159616569 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 477.3;Oligodendrocytes: 604.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 115.8;neutrophil: 213.2" "Lineage enriched" "Detected in all" 8 "granulocytes: 213.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019819, HPA059292" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA019819: AB_1845282, HPA059292: AB_2683968" "unprognostic (2.27e-1)" "unprognostic (1.67e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-2)" "unprognostic (4.94e-3)" "unprognostic (1.19e-1)" "unprognostic (5.64e-2)" "unprognostic (5.49e-3)" "unprognostic (9.01e-2)" "unprognostic (2.29e-1)" "unprognostic (1.44e-1)" "unprognostic (1.27e-1)" "unprognostic (2.14e-1)" "unprognostic (3.30e-1)" "unprognostic (1.06e-2)" "unprognostic (2.14e-2)" 20.6 23.8 23.0 18.1 43.7 36.7 22.1 57.4 26.8 23.8 3.6 18.2 17.1 33.6 19.7 22.1 24.4 26.1 18.4 21.8 41.4 17.3 16.8 24.7 14.7 45.3 29.1 42.4 19.3 24.6 17.5 20.5 47.7 18.4 16.4 52.0 23.4 19.8 18.4 17.5 18.5 23.5 26.0 20.9 17.0 26.4 43.7 21.5 25.4 22.3 13.6 20.9 14.7 75.3 7.4 14.7 48.4 29.4 14.2 22.8 8.4 15.3 18.7 8.2 9.6 22.1 19.9 12.4 25.8 15.0 8.4 16.6 19.4 20.7 13.0 4.5 11.1 24.7 26.9 3.1 9.3 16.3 17.0 18.0 22.2 20.6 22.2 30.4 42.5 8.3 25.7 2.3 13.1 9.1 5.6 10.5 16.1 1.5 12.4 13.1 15.7 8.8 16.4 26.2 32.1 27.9 30.3 3.7 18.5 25.0 5.8 46.7 42.6 14.9 30.1 6.5 10.3 9.0 1.0 14.0 14.1 17.5 10.0 115.8 27.4 36.4 10.1 12.0 8.3 6.5 6.1 10.5 17.7 9.6 4.1 6.6 213.2 19.7 11.3 24.5 7.1 6.0 23.0 43.7 57.4 26.8 21.8 41.4 45.3 29.1 47.7 26.0 43.7 75.3 105.3 99.3 148.0 477.3 34.3 32.6 70.1 35.8 66.0 91.8 56.4 38.9 60.8 61.5 71.5 68.0 310.6 18.5 40.1 45.4 9.8 55.5 158.0 69.8 63.9 82.5 99.9 42.1 180.4 38.9 7.2 54.9 59.7 118.9 73.9 71.9 71.0 29.4 25.5 94.2 177.3 52.1 36.7 58.0 37.1 35.4 59.4 76.6 14.2 289.5 81.4 87.3 41.2 300.6 604.3 54.3 55.5 35.0 42.2 50.0 51.7 12.4 73.3 332.3 13.1 74.9 54.1 98.2 20.7 49.6 37.5 26.7 38.9 83.2 48.6 91.6 BBC3 "JFY1, PUMA" ENSG00000105327 "BCL2 binding component 3" "Q96PG8, Q9BXH1" 19 47220822-47232766 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.4;Basal squamous epithelial cells: 111.5;Prostatic glandular cells: 132.9;Suprabasal keratinocytes: 143.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 4.5;neutrophil: 3.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "HHSteC: 28.4;NB-4: 34.9" "CAB007752, HPA070403" Approved Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB007752: AB_562336, HPA070403: " "unprognostic (4.39e-2)" "unprognostic (2.02e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.31e-4)" "unprognostic (2.95e-2)" "unprognostic (4.74e-2)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "unprognostic (1.93e-1)" "unprognostic (8.38e-3)" "unprognostic (7.21e-2)" "unprognostic (2.22e-1)" "unprognostic (2.66e-2)" "unprognostic (4.66e-3)" "unprognostic (5.06e-2)" "unprognostic (3.57e-1)" "prognostic favorable (2.62e-5)" 3.1 4.4 3.1 2.1 2.8 4.8 4.0 4.3 4.7 3.2 1.8 6.4 2.4 3.4 0.6 1.9 3.6 2.0 3.9 3.3 2.4 5.1 5.6 7.7 2.7 2.8 3.7 3.2 7.7 2.0 2.1 1.9 2.9 4.1 1.8 0.2 7.5 1.2 10.4 8.2 5.0 0.7 2.3 6.1 5.0 2.6 2.8 4.0 3.1 1.1 0.8 4.9 3.4 2.5 3.8 8.3 9.0 1.9 2.1 4.1 22.1 5.9 7.9 1.4 3.5 2.5 6.3 14.7 2.5 1.5 2.5 1.2 1.3 5.3 0.2 9.3 15.9 4.2 2.8 16.4 28.4 0.7 13.4 9.8 8.4 3.0 2.8 3.7 10.3 4.4 10.9 9.0 1.0 8.6 1.6 34.9 5.6 6.5 1.1 4.1 1.3 17.7 0.4 1.3 1.5 13.5 2.7 5.6 18.7 7.1 1.9 11.7 6.9 1.7 11.1 0.2 1.9 14.4 3.4 9.5 2.6 2.2 6.2 4.5 0.4 0.2 0.4 0.5 0.4 0.1 0.1 0.3 0.2 0.0 0.5 0.3 3.4 0.6 0.4 0.1 0.3 0.2 3.1 2.8 4.3 4.7 3.3 2.4 2.8 3.7 2.9 2.3 2.8 2.5 16.2 9.6 7.4 1.6 21.7 117.4 78.8 40.3 111.5 6.5 46.4 29.1 5.6 10.0 21.8 7.3 0.0 4.7 28.3 51.9 0.0 52.4 14.6 65.2 14.0 15.8 21.4 16.8 3.2 39.8 5.5 12.1 23.4 66.2 12.7 8.4 3.9 3.5 7.1 0.0 3.9 40.6 30.5 10.3 31.9 3.3 6.2 17.1 64.0 2.8 15.7 3.7 32.0 1.0 0.5 55.2 49.3 4.1 19.3 132.9 16.2 4.1 22.9 4.4 6.6 12.4 34.9 0.5 1.7 59.4 143.3 20.5 28.5 10.2 27.4 66.2 BBS4 ENSG00000140463 "Bardet-Biedl syndrome 4" Q96RK4 15 72686179-72738475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 120.9;Rod photoreceptor cells: 89.9;Spermatocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 62.3" "Low region specificity" "Detected in all" HPA039418 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 18: U-2197 - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA039418: AB_10672962" "unprognostic (3.47e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" "prognostic favorable (2.57e-4)" "unprognostic (3.54e-1)" "unprognostic (2.91e-1)" "unprognostic (8.76e-2)" "unprognostic (5.47e-2)" "unprognostic (5.70e-2)" "unprognostic (2.56e-1)" "unprognostic (3.22e-3)" "unprognostic (1.26e-1)" "unprognostic (5.15e-2)" "unprognostic (4.87e-2)" "unprognostic (1.56e-1)" "unprognostic (1.11e-1)" "unprognostic (3.05e-1)" 9.5 14.8 11.0 6.8 11.2 7.7 10.9 10.1 13.1 13.3 18.1 12.0 5.1 12.5 15.4 5.8 17.5 9.3 11.1 10.9 11.9 15.6 12.7 10.4 8.0 10.9 12.4 14.0 11.1 17.4 20.7 7.9 12.6 20.7 7.6 45.4 7.9 9.4 18.7 9.2 7.9 9.3 10.9 7.6 11.0 20.4 11.5 11.5 16.1 10.2 7.0 11.1 9.1 11.0 6.1 15.7 34.0 14.4 16.5 19.7 9.0 11.9 24.4 11.3 14.8 8.1 20.2 9.6 24.7 10.2 8.6 9.4 9.1 9.9 10.3 10.0 11.0 11.4 13.3 9.2 13.5 10.2 8.6 18.8 13.2 16.3 12.8 17.1 8.9 18.3 25.4 8.2 18.1 10.7 9.6 9.6 48.8 12.3 6.8 6.4 17.1 12.3 19.2 15.2 16.4 19.2 20.8 15.0 31.2 13.1 20.4 11.3 12.5 13.2 10.0 62.3 6.7 17.1 17.8 21.0 14.9 15.3 18.1 5.5 1.9 3.3 5.1 2.9 4.9 4.8 4.3 5.5 1.6 6.0 4.3 5.9 1.6 11.0 2.5 3.1 5.7 2.8 11.0 11.2 10.1 13.1 10.9 11.9 10.9 12.4 12.6 10.9 11.5 11.0 6.0 19.2 19.2 35.3 8.3 3.1 6.0 9.4 10.8 39.0 8.4 10.5 19.8 4.3 18.2 12.9 120.9 10.0 10.6 3.5 5.9 14.4 19.9 28.8 11.1 8.1 4.2 5.2 18.6 11.3 5.8 12.4 7.7 8.4 13.9 8.7 7.1 7.4 7.8 21.9 22.8 8.0 6.1 5.8 2.4 12.2 15.8 5.9 5.4 19.7 4.4 39.4 9.2 31.7 30.7 8.9 4.9 20.3 9.0 8.0 5.1 9.4 48.8 89.9 0.0 11.0 11.5 79.0 63.6 4.6 2.8 5.3 9.3 24.3 5.1 2.8 BCAM "CD239, LU" ENSG00000187244 "Basal cell adhesion molecule (Lutheran blood group)" P50895 19 44809071-44821421 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Blood group antigen, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 316.8" "Cell type enhanced" "Detected in many" "Adipocytes: 374.9;Basal respiratory cells: 454.1;Collecting duct cells: 548.1;Cytotrophoblasts: 705.4;Syncytiotrophoblasts: 433.3" "Cancer enhanced" "Detected in all" "ovarian cancer: 493.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 142.7;HaCaT: 298.4;SK-BR-3: 276.8;T-47d: 157.2;U-2 OS: 130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005654 Enhanced Approved "Nucleoli fibrillar center" NA NA 18000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoli fibrillar center" "HPA005654: AB_2667378" "unprognostic (5.63e-2)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "prognostic unfavorable (1.24e-5)" "unprognostic (1.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.01e-1)" "unprognostic (2.25e-2)" "unprognostic (1.60e-1)" "unprognostic (6.17e-2)" "unprognostic (2.61e-3)" "unprognostic (1.41e-1)" "prognostic favorable (5.94e-6)" "unprognostic (1.83e-2)" "unprognostic (5.74e-2)" "unprognostic (2.14e-2)" "unprognostic (9.97e-3)" 105.0 23.3 24.0 9.9 23.3 3.8 125.6 23.7 39.6 87.7 38.2 32.2 13.5 78.1 21.3 29.1 115.1 15.8 118.3 21.3 24.6 316.8 38.4 89.0 9.8 26.7 27.4 50.2 51.5 20.0 38.3 44.1 26.7 130.1 5.3 3.1 65.6 49.2 44.7 54.1 31.2 19.6 24.0 36.4 39.3 20.6 28.2 13.8 215.7 30.8 7.1 52.8 72.0 21.6 34.7 44.3 1.2 120.8 0.6 0.8 142.7 13.3 6.3 10.7 7.1 66.8 83.5 0.0 65.7 1.6 0.6 298.4 10.4 74.5 3.2 0.1 7.3 0.2 8.8 93.9 23.6 0.0 15.9 11.6 28.6 3.7 4.4 34.2 6.6 0.0 7.3 0.5 1.6 17.7 0.4 1.2 13.5 10.0 15.1 0.5 14.2 3.6 90.4 21.9 0.4 0.5 54.0 276.8 3.4 13.1 157.2 5.1 17.4 2.7 130.2 3.4 6.5 0.6 1.4 0.1 1.1 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 23.3 23.7 39.6 21.3 24.6 26.7 27.4 26.7 24.0 28.2 21.6 374.9 6.4 12.3 5.5 4.4 40.7 118.0 454.1 80.2 2.5 109.5 185.4 12.8 52.9 48.5 548.1 0.0 705.4 3.2 8.6 82.2 34.0 1.3 62.9 8.2 214.0 52.0 4.8 0.5 4.0 36.9 21.7 15.8 45.3 0.0 14.3 73.2 31.0 44.7 0.0 1.2 5.6 40.7 8.0 21.3 2.1 29.5 3.5 16.0 9.4 0.1 23.6 0.0 1.0 0.3 14.3 21.4 15.1 2.5 80.4 4.9 149.6 20.7 1.1 157.8 14.1 240.6 3.2 18.3 8.9 24.6 433.3 3.5 6.4 13.0 40.7 BCAN "BEHAB, CSPG7, MGC13038" ENSG00000132692 Brevican Q96GW7 1 156641390-156659532 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 164.7" "Group enriched" "Detected in some" 8 "Astrocytes: 136.1;Horizontal cells: 109.4;Melanocytes: 186.7;Oligodendrocyte precursor cells: 288.0" "Cancer enriched" "Detected in many" 5 "glioma: 348.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "basophil: 7.8" "Lineage enriched" "Detected in single" 24 "granulocytes: 7.8" "Cell line enhanced" "Detected in many" "HDLM-2: 76.7;K-562: 108.3;U-266/70: 63.3;U-266/84: 133.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007865, CAB025862" Enhanced Supported "Secreted in brain" NA NA 120000 "Cluster 34: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 16: U-266 - Nucleosome" "Cluster 68: Oligodendrocytes - Mixed function" "CAB025862: , HPA007865: AB_1078299" "unprognostic (7.14e-2)" "unprognostic (3.14e-1)" "unprognostic (1.95e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (9.03e-2)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (4.80e-2)" "unprognostic (6.87e-2)" "unprognostic (1.65e-1)" "unprognostic (1.30e-2)" "unprognostic (9.47e-3)" "unprognostic (2.76e-2)" "unprognostic (8.54e-2)" "unprognostic (5.40e-1)" "unprognostic (1.90e-1)" 0.2 8.4 155.0 0.6 119.5 0.0 0.2 108.3 164.7 2.7 38.3 2.2 7.0 5.9 15.4 0.6 4.0 3.4 0.5 133.1 104.8 0.2 0.1 0.4 0.3 107.5 100.0 0.2 0.1 1.7 2.8 0.7 103.4 0.2 0.0 4.1 1.6 1.8 0.6 15.6 7.8 2.0 94.3 0.5 2.2 1.2 113.7 0.1 0.2 0.0 0.0 0.9 0.9 116.3 44.2 28.4 0.2 8.1 0.0 0.0 11.9 0.4 0.0 0.0 0.0 1.1 21.0 0.1 45.8 0.0 1.0 30.9 0.3 0.0 0.0 76.7 2.9 8.0 20.9 25.6 0.0 3.0 7.3 0.0 0.0 0.0 0.0 1.0 0.0 3.8 108.3 21.0 0.0 12.6 0.1 0.1 2.2 22.2 4.2 0.1 46.7 0.1 0.0 5.4 0.2 0.8 0.1 0.0 43.8 2.2 0.2 2.8 8.8 0.1 24.7 8.7 11.8 63.3 133.2 0.2 8.5 20.4 3.4 7.8 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.0 119.5 108.3 164.7 133.1 104.8 107.5 100.0 103.4 94.3 113.7 116.3 0.2 0.0 0.0 136.1 0.0 6.9 0.0 0.0 0.0 6.0 0.2 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.1 2.9 0.1 1.8 0.7 1.8 0.0 16.8 0.2 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.5 109.4 20.2 0.1 0.0 0.0 1.9 6.9 0.3 0.1 186.7 9.4 0.0 2.1 1.0 288.0 3.5 0.8 0.1 0.0 0.0 0.3 0.1 0.4 0.0 3.2 0.0 0.2 1.7 5.4 6.5 0.0 1.7 0.0 0.2 0.0 0.0 0.0 BCAP29 "BAP29, DKFZp686M2086" ENSG00000075790 "B cell receptor associated protein 29" Q9UHQ4 7 107580246-107629170 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029215, HPA049694" Supported Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA029215: AB_10602331, HPA049694: AB_2680854" "unprognostic (3.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.82e-2)" "unprognostic (1.05e-2)" "unprognostic (5.42e-3)" "unprognostic (4.71e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.43e-2)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (2.31e-2)" "unprognostic (7.36e-2)" "unprognostic (8.34e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-2)" "unprognostic (5.28e-3)" "unprognostic (1.81e-1)" 47.1 25.7 19.4 22.5 23.7 16.7 28.0 18.1 27.0 48.6 12.8 32.6 16.1 42.6 18.6 34.4 21.7 23.0 61.0 24.4 17.9 20.1 33.3 26.0 16.7 17.5 17.6 21.4 18.9 34.5 12.2 26.7 18.0 31.9 31.2 9.6 18.4 25.0 38.7 22.1 18.8 38.2 19.5 18.1 22.4 70.1 19.2 12.8 85.5 31.5 15.7 30.9 32.5 21.1 71.7 22.8 26.4 13.8 65.2 81.6 22.6 80.6 68.2 32.9 39.7 23.2 72.1 13.4 54.5 58.1 75.1 35.8 13.7 38.6 52.5 50.1 17.3 27.1 35.6 26.2 63.3 33.6 41.2 48.9 31.8 46.7 38.0 95.4 116.9 25.3 58.3 33.4 75.4 67.2 23.2 34.3 15.4 29.7 30.0 18.6 34.1 34.6 60.6 49.1 10.2 37.7 68.2 54.9 58.2 39.3 25.6 37.5 113.9 102.5 52.1 94.6 104.7 31.7 67.9 27.5 66.5 30.5 77.2 47.5 10.5 25.5 9.5 13.6 9.3 12.8 7.5 9.5 10.0 8.5 4.3 8.5 3.9 9.9 21.7 10.1 13.6 8.1 19.4 23.7 18.1 27.0 24.4 17.9 17.5 17.6 18.0 19.5 19.2 21.1 169.8 67.3 57.2 35.6 33.9 38.5 80.7 99.0 25.0 35.2 40.4 34.2 117.8 27.1 77.7 23.9 10.4 30.2 31.4 38.1 15.6 46.4 227.1 54.6 93.3 99.0 22.3 73.2 81.1 73.6 50.8 72.9 32.6 102.0 58.3 14.8 73.2 40.7 52.6 8.4 71.3 35.8 69.2 36.6 35.6 95.8 61.2 49.6 37.4 44.0 41.6 28.3 22.6 50.8 49.7 71.2 32.5 89.1 17.7 110.4 15.6 19.5 55.9 26.7 78.9 62.9 91.3 202.2 35.0 46.5 38.8 70.7 33.5 32.0 45.4 83.5 BCAR1 "CAS, CASS1, Crkas, P130Cas" ENSG00000050820 "BCAR1 scaffold protein, Cas family member" P56945 16 75228181-75268053 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000443, HPA042282" Approved Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB000443: , HPA042282: AB_2677929" "unprognostic (5.44e-2)" "unprognostic (2.96e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-2)" "unprognostic (2.17e-1)" "unprognostic (5.43e-3)" "prognostic unfavorable (9.11e-5)" "prognostic unfavorable (1.24e-4)" "unprognostic (2.15e-1)" "unprognostic (3.49e-2)" "unprognostic (5.18e-2)" "unprognostic (1.77e-2)" "prognostic favorable (4.55e-8)" "unprognostic (3.38e-1)" "unprognostic (3.60e-2)" "unprognostic (8.20e-2)" "unprognostic (2.20e-1)" 34.7 22.3 3.5 4.2 5.8 0.0 27.9 16.9 6.6 37.7 6.3 34.4 15.8 39.2 2.6 22.5 25.3 9.4 47.1 2.3 7.9 47.3 34.2 38.8 2.1 3.9 1.9 19.7 32.4 5.9 29.5 14.1 2.3 25.6 3.5 1.3 25.5 5.7 93.8 18.2 33.1 3.8 0.0 33.7 44.6 34.3 4.2 0.9 26.8 6.8 1.1 24.9 26.2 15.8 21.8 36.8 17.5 6.0 6.7 6.3 34.1 29.5 17.1 20.9 16.4 46.5 32.1 1.9 38.2 33.3 23.6 18.2 6.1 34.0 6.0 0.1 20.0 0.0 23.7 37.2 16.7 0.1 15.1 19.1 16.3 25.3 12.5 12.3 57.9 0.0 20.0 1.0 12.6 48.9 0.1 1.3 23.4 16.1 24.0 0.8 7.9 8.2 19.1 27.9 21.4 31.5 28.7 6.6 11.2 8.4 15.0 5.4 53.6 34.4 29.5 8.8 44.2 8.0 4.7 0.7 22.2 0.1 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 16.9 6.6 2.3 7.9 3.9 1.9 2.3 0.0 4.2 15.8 30.1 22.4 6.9 9.4 1.2 28.0 59.7 36.8 12.0 26.5 20.3 14.4 22.9 31.5 21.8 22.0 6.2 46.8 0.7 75.7 27.4 51.9 19.0 13.7 27.9 49.2 34.8 0.0 13.1 61.8 25.7 21.1 71.9 22.5 8.9 15.0 46.8 21.0 6.0 13.5 11.7 42.1 12.2 1.4 6.3 26.8 16.4 2.1 32.0 10.3 0.6 12.9 0.0 19.1 31.2 68.5 59.6 33.4 1.4 58.4 57.4 38.9 13.1 6.8 19.7 8.5 38.5 20.6 17.1 12.5 17.6 36.1 2.2 10.9 33.7 62.7 BCHE "CHE1, CHE2, E1" ENSG00000114200 Butyrylcholinesterase P06276 3 165772904-165837462 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 525.1" "Group enriched" "Detected in many" 9 "Hepatocytes: 420.3;Oligodendrocyte precursor cells: 210.1" "Group enriched" "Detected in many" 6 "glioma: 24.0;liver cancer: 13.7;melanoma: 18.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "Karpas-707: 785.6" "Low region specificity" "Detected in all" HPA001560 Approved "Secreted to blood" NA NA 9400000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "HPA001560: AB_1078271" "unprognostic (4.74e-2)" "unprognostic (2.00e-1)" "unprognostic (9.21e-4)" "unprognostic (8.19e-8)" "unprognostic (2.66e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.44e-1)" "unprognostic (5.04e-2)" "unprognostic (6.15e-2)" "unprognostic (9.59e-2)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" "unprognostic (3.18e-3)" "unprognostic (4.46e-5)" "unprognostic (2.17e-2)" "unprognostic (5.92e-2)" "unprognostic (4.26e-4)" 30.4 11.6 9.3 2.7 7.4 0.0 4.7 7.5 12.0 22.0 5.0 36.1 4.7 41.0 24.3 25.8 36.2 6.0 9.7 7.9 7.3 4.9 525.1 10.9 0.2 7.9 9.4 3.7 2.3 0.1 1.8 0.0 7.8 12.5 16.1 8.8 1.9 32.3 2.7 8.7 10.6 29.7 7.4 5.9 3.5 1.3 12.2 2.9 1.3 5.1 0.1 11.3 5.1 9.4 0.0 2.1 82.1 0.1 0.2 0.0 0.1 0.0 1.5 0.6 7.3 0.0 0.1 0.3 30.7 0.0 0.0 0.5 5.7 0.4 5.8 0.4 0.8 0.0 0.0 0.0 6.3 0.2 0.4 23.5 1.4 0.0 8.1 25.3 3.6 30.0 0.0 785.6 0.0 0.0 0.0 0.1 2.1 0.0 0.8 0.0 28.4 67.3 0.7 0.0 0.0 0.8 0.1 0.0 46.5 0.0 34.0 0.2 0.0 19.3 0.5 0.0 8.3 3.5 0.0 1.6 8.2 0.2 84.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 7.4 7.5 12.0 7.9 7.3 7.9 9.4 7.8 7.4 12.2 9.4 5.8 0.0 0.0 1.0 0.7 5.5 0.9 0.0 1.8 1.4 0.0 0.1 9.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.6 0.0 0.7 3.4 0.0 8.0 3.0 0.0 0.0 22.0 0.5 0.0 0.0 0.2 8.9 420.3 0.1 1.7 10.5 0.4 0.0 4.7 1.5 8.7 2.1 0.3 19.6 3.7 0.0 31.7 0.0 210.1 16.1 0.0 0.0 0.0 0.0 0.2 0.0 3.7 0.0 1.2 0.0 0.8 6.5 0.3 0.3 0.6 3.4 0.0 1.1 0.1 0.0 0.1 BCKDK ENSG00000103507 "Branched chain keto acid dehydrogenase kinase" O14874 16 31106107-31112791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 95.9;granulocytes: 89.7;monocytes: 115.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017995, HPA056067" Supported Supported Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA017995: AB_1845309, HPA056067: AB_2683024" "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (6.94e-2)" "unprognostic (5.20e-2)" "unprognostic (5.39e-2)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (5.47e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.24e-2)" "unprognostic (2.66e-3)" "unprognostic (4.85e-2)" "unprognostic (3.93e-2)" "unprognostic (1.00e-1)" "unprognostic (4.97e-2)" 32.3 56.4 18.4 19.2 18.6 14.5 29.0 17.4 23.8 25.1 18.0 31.4 16.0 27.7 16.7 29.4 24.8 17.9 78.6 18.8 17.8 43.8 76.4 21.7 15.6 20.6 20.7 27.5 70.5 22.9 16.4 15.3 19.3 29.3 12.5 6.3 47.0 21.8 81.3 45.4 24.1 19.5 17.1 30.2 42.0 17.4 18.5 9.8 22.4 69.7 13.6 30.2 24.6 17.5 47.5 49.1 27.1 41.8 32.8 32.5 31.1 40.4 46.3 57.3 55.9 32.1 29.1 41.5 58.9 47.5 28.0 31.4 19.3 65.6 36.5 34.4 60.1 45.2 32.6 59.5 57.5 23.5 41.9 48.3 26.2 49.2 40.6 52.6 62.4 31.1 23.4 39.4 87.7 75.8 22.9 32.4 23.0 20.5 39.1 45.8 39.6 78.8 44.3 30.1 42.1 38.7 31.3 72.4 24.6 22.9 44.5 24.6 41.1 44.2 26.1 45.8 32.2 44.5 15.7 15.1 50.3 33.7 42.6 58.1 115.0 85.2 17.7 97.6 17.2 22.8 16.5 13.9 95.9 19.0 13.6 16.1 89.7 22.8 71.2 19.3 24.5 53.1 18.4 18.6 17.4 23.8 18.8 17.8 20.6 20.7 19.3 17.1 18.5 17.5 27.2 19.2 18.1 5.9 20.0 18.5 24.6 61.0 22.2 11.6 30.9 27.6 39.1 25.8 28.5 20.2 0.0 55.4 9.0 31.5 80.3 68.6 2.5 14.6 24.3 29.2 19.9 16.4 5.1 78.0 71.1 24.9 25.5 20.0 33.0 35.4 25.4 43.8 93.0 11.8 4.4 22.3 42.7 44.5 50.3 7.8 20.8 53.1 12.4 1.9 79.3 22.6 9.2 4.5 4.5 54.8 48.4 25.6 51.7 30.9 66.9 95.2 19.6 9.8 46.0 18.4 33.2 25.8 14.1 25.7 27.4 69.4 12.1 45.5 26.0 27.0 BCL2 "Bcl-2, PPP1R50" ENSG00000171791 "BCL2 apoptosis regulator" P10415 18 63123346-63320128 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 271.6;Inhibitory neurons: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 18 "B-cells: 5.4;T-cells: 8.5" "Cell line enhanced" "Detected in many" "HDLM-2: 44.2;HL-60: 43.7;Karpas-707: 72.9;U-266/70: 217.4" "Low region specificity" "Detected in all" "CAB000003, HPA055295" Enhanced Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear membrane" Nucleoplasm "CAB000003: AB_2064429, HPA055295: AB_2682776" "unprognostic (1.11e-3)" "prognostic favorable (5.13e-5)" "unprognostic (5.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.93e-3)" "unprognostic (4.78e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-2)" "unprognostic (8.51e-2)" "prognostic favorable (1.29e-8)" "unprognostic (6.67e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (2.63e-1)" 12.8 1.9 5.5 10.2 7.8 5.0 9.6 4.7 3.4 10.7 0.0 6.2 4.4 11.6 2.9 5.9 11.8 6.5 5.3 2.9 6.6 6.7 2.1 3.7 14.7 11.2 7.9 14.5 3.1 13.0 4.7 4.6 7.5 6.4 5.5 2.1 3.7 7.0 16.5 4.8 8.1 6.6 7.9 17.9 3.8 1.5 8.2 18.3 24.0 8.8 14.6 5.4 7.7 5.7 1.7 0.3 6.8 5.9 6.7 1.3 2.4 1.0 0.7 2.4 2.0 3.5 0.4 0.3 1.1 0.9 4.7 0.4 6.7 0.9 1.5 44.2 1.6 0.5 2.0 0.7 2.0 43.7 5.6 1.7 0.8 3.3 5.8 1.1 0.7 4.3 0.8 72.9 2.2 1.4 9.8 10.7 1.5 0.8 1.3 39.5 1.9 26.5 7.4 8.5 7.2 6.4 0.3 0.3 8.5 1.4 0.3 29.9 0.3 9.9 3.3 0.9 5.1 217.4 40.1 2.9 1.9 24.9 6.0 0.3 0.0 0.0 1.9 0.0 7.6 5.4 6.3 3.4 0.1 3.1 3.3 3.2 0.0 0.2 0.3 0.2 8.5 1.3 5.5 7.8 4.7 3.4 2.9 6.6 11.2 7.9 7.5 7.9 8.2 5.7 7.1 0.0 1.1 271.6 84.9 19.5 33.6 1.6 13.6 1.9 39.7 19.7 17.4 18.6 2.4 7.3 0.0 14.0 39.9 2.7 15.6 3.7 0.4 9.8 9.8 5.9 5.4 3.8 60.7 0.0 0.7 15.8 5.6 24.9 15.8 38.8 3.9 1.2 9.4 0.0 102.3 10.5 24.4 15.0 29.6 1.9 8.7 29.0 46.2 88.1 19.7 18.8 18.6 76.4 56.7 0.2 5.9 13.9 50.1 41.6 0.9 18.0 0.1 0.6 26.3 48.8 19.7 0.3 1.3 6.2 17.6 49.1 76.1 24.1 9.8 76.2 BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 38.5;Bipolar cells: 13.8;Cardiomyocytes: 9.1;Excitatory neurons: 22.3;Smooth muscle cells: 25.8;Theca cells: 9.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 36.6;BJ hTERT+ SV40 Large T+: 28.0;BJ hTERT+ SV40 Large T+ RasG12V: 20.9;HBF TERT88: 26.5;U-138 MG: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009564, HPA031440, HPA056104" Enhanced Supported "Nuclear speckles,Mitochondria" "Secreted to blood" NA Yes 16000000 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Mitochondria" "CAB009564: AB_2064213, HPA031440: AB_2673883, HPA056104: AB_2683038" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" 0.4 0.5 1.9 0.2 2.4 0.2 0.2 3.3 5.3 0.6 0.1 0.4 0.3 0.2 3.3 0.6 0.1 0.7 3.6 8.2 1.9 0.6 0.1 2.0 0.1 3.3 2.1 0.5 0.4 0.0 1.2 1.6 2.5 2.0 0.1 0.7 0.3 1.8 0.4 0.9 0.1 0.1 0.4 0.1 0.3 0.6 1.6 0.3 1.0 0.0 0.1 2.1 0.6 0.8 2.9 12.2 0.3 0.0 3.7 2.2 0.0 36.6 7.9 28.0 20.9 0.1 4.0 0.0 3.7 11.8 0.5 1.4 0.1 0.2 26.5 0.2 0.1 0.0 3.5 0.0 17.4 0.2 0.2 9.2 4.2 6.8 3.7 18.1 1.3 0.1 0.0 0.1 4.8 0.0 0.0 0.0 4.0 0.1 2.9 0.0 2.0 0.0 4.5 0.0 0.2 1.1 7.8 0.1 0.1 1.7 0.2 0.0 11.0 37.6 6.9 14.4 9.2 0.5 0.1 0.0 14.1 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.4 3.3 5.3 8.2 1.9 3.3 2.1 2.5 0.4 1.6 0.8 0.2 38.5 0.5 1.6 0.0 0.6 0.4 0.5 1.8 13.8 0.5 0.9 9.1 0.0 0.4 1.8 4.2 0.4 0.0 0.1 0.0 0.8 1.8 0.3 0.3 0.2 0.0 0.0 22.3 0.0 0.5 6.1 0.0 0.1 1.3 1.9 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.4 1.5 0.3 0.9 1.8 0.0 0.0 0.2 0.0 2.0 2.2 0.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 1.8 0.0 1.8 25.8 3.7 0.8 2.3 0.0 0.7 0.0 9.3 0.1 0.1 BGLAP OCN ENSG00000242252 "Bone gamma-carboxyglutamate protein" P02818 1 156242184-156243317 "FDA approved drug targets, Predicted secreted proteins" Biomineralization "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 19.9;choroid plexus: 10.8;intestine: 8.5" "Cell type enhanced" "Detected in some" "Ionocytes: 4.1;Melanocytes: 3.6;Plasma cells: 2.8;Sertoli cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "NK-cell: 1.8;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 17 "dendritic cells: 1.6;NK-cells: 1.8" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 8.3;U-87 MG: 5.4" "Region enriched" "Detected in single" 9 "olfactory bulb: 7.8" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 15500000 2200000 "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.50e-2)" "unprognostic (4.49e-2)" "unprognostic (3.82e-4)" "unprognostic (1.13e-1)" "unprognostic (1.57e-1)" "unprognostic (8.44e-5)" "unprognostic (2.63e-2)" "unprognostic (6.54e-2)" "unprognostic (5.64e-2)" "unprognostic (2.00e-1)" "unprognostic (1.53e-3)" "unprognostic (4.70e-2)" "unprognostic (9.67e-6)" "unprognostic (3.02e-2)" "unprognostic (1.72e-1)" "unprognostic (4.34e-2)" "unprognostic (8.64e-3)" 0.7 0.5 12.7 0.6 13.9 0.9 0.6 13.3 19.9 1.7 10.8 8.5 0.6 1.4 1.1 0.7 1.4 0.6 0.8 12.3 12.7 1.1 1.6 0.6 0.4 14.6 13.4 1.9 0.8 0.2 1.1 0.4 13.5 2.0 1.8 0.2 1.7 0.7 0.5 1.7 2.3 1.8 14.0 1.9 0.8 0.4 13.4 0.3 1.4 0.0 0.2 0.8 1.0 14.7 0.1 1.5 0.7 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.5 0.5 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.5 0.1 0.2 0.4 0.0 0.0 0.7 0.6 0.1 0.3 0.7 0.1 0.4 1.8 0.0 0.2 0.6 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.7 1.1 1.4 5.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.6 0.0 0.0 12.7 13.9 13.3 19.9 12.3 12.7 14.6 13.4 13.5 14.0 13.4 14.7 0.6 0.0 0.0 0.0 0.6 1.5 1.0 1.0 0.6 0.2 1.1 0.9 0.0 0.0 1.0 0.0 0.0 0.5 0.2 0.1 0.0 0.1 0.1 0.3 0.4 0.6 0.0 0.0 0.0 0.2 0.3 1.0 0.5 0.5 0.0 1.1 1.1 0.2 0.2 0.0 0.0 0.9 4.1 0.0 0.8 0.2 1.5 0.5 3.6 0.0 0.4 0.4 1.0 0.0 0.0 0.0 1.1 0.4 2.8 0.7 0.3 2.0 0.3 0.6 6.6 0.5 0.3 0.4 0.8 0.6 1.3 0.4 0.6 0.8 0.8 0.7 BGN "DSPG1, SLRR1A" ENSG00000182492 Biglycan P21810 X 153494980-153509546 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 795.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 223.5;Peritubular cells: 782.7;Sertoli cells: 1485.7;Smooth muscle cells: 401.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 312.6;BJ hTERT+: 400.8;fHDF/TERT166: 568.9;HSkMC: 283.9;hTEC/SVTERT24-B: 235.2;HUVEC TERT2: 561.2;U-138 MG: 249.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003157, CAB003678" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 3300000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Endoplasmic reticulum" "CAB003678: AB_425325, HPA003157: AB_1078282" "unprognostic (1.74e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-3)" "unprognostic (3.60e-1)" "unprognostic (5.42e-2)" "unprognostic (3.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.22e-2)" "unprognostic (1.76e-3)" "unprognostic (1.30e-2)" "unprognostic (2.63e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (6.00e-8)" "unprognostic (7.05e-3)" "unprognostic (2.40e-2)" "unprognostic (5.66e-2)" "unprognostic (2.57e-3)" 165.8 213.0 54.1 93.1 57.6 0.3 118.0 51.2 91.5 371.0 69.5 69.3 22.0 234.4 83.7 45.8 143.7 326.1 795.8 56.1 48.7 396.5 347.9 477.3 42.4 50.6 50.8 94.9 67.9 26.6 144.1 199.1 53.2 184.2 24.8 1.1 107.7 135.5 32.4 118.9 48.8 213.2 45.5 352.1 51.6 69.9 64.6 15.9 250.0 46.7 35.9 126.8 180.0 65.4 0.0 0.0 29.7 0.1 31.5 70.5 1.1 312.6 400.8 56.7 18.6 39.5 0.0 0.0 56.9 568.9 2.0 0.1 0.0 0.0 10.2 0.0 0.0 0.0 0.6 3.9 27.0 0.0 0.2 283.9 2.2 235.2 10.7 29.0 561.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.0 1.5 0.3 0.2 0.0 0.1 0.0 0.6 0.4 0.0 0.0 1.1 11.8 1.3 0.0 120.0 249.5 2.3 1.0 1.5 0.9 0.1 0.0 0.1 0.3 114.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 57.6 51.2 91.5 56.1 48.7 50.6 50.8 53.2 45.5 64.6 65.4 30.5 3.2 5.6 5.9 0.6 104.1 1.3 7.3 5.7 0.2 1.2 5.6 16.1 4.3 2.5 9.2 0.0 15.5 0.7 0.0 1.9 2.7 1.8 1.4 28.3 45.2 0.0 5.3 0.1 0.2 50.0 180.0 7.7 1.1 3.8 8.4 223.5 1.6 4.4 3.3 0.1 0.0 0.0 4.0 43.6 13.5 147.9 3.0 35.6 25.3 2.0 0.1 0.0 20.6 0.0 1.2 0.0 782.7 0.0 3.0 0.0 0.8 1.6 0.2 1485.7 3.1 401.3 0.8 1.2 1.8 54.1 56.9 3.0 7.7 0.0 1.6 BIRC2 "API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48" ENSG00000110330 "Baculoviral IAP repeat containing 2" Q13490 11 102347211-102378670 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005513, CAB020661" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli fibrillar center, Cytosol" Nucleoplasm "CAB020661: , HPA005513: AB_1846746" "unprognostic (1.36e-1)" "unprognostic (3.29e-1)" "unprognostic (9.52e-3)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (7.02e-2)" "unprognostic (2.72e-2)" "unprognostic (1.04e-2)" "unprognostic (1.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.05e-2)" "unprognostic (3.02e-2)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (9.20e-2)" "unprognostic (5.00e-2)" "unprognostic (1.64e-2)" 23.2 27.6 18.4 25.8 19.6 36.4 28.2 20.0 23.4 27.5 22.5 27.2 23.6 25.7 30.2 18.1 19.7 24.8 23.6 17.9 19.9 28.8 44.3 22.6 34.5 19.7 19.4 21.8 33.7 20.4 18.8 29.4 19.8 21.4 26.0 22.2 21.1 16.1 29.7 18.2 25.2 21.6 20.1 26.7 23.5 24.6 18.8 50.6 22.2 32.9 27.1 30.4 20.4 24.9 34.0 24.7 37.3 29.3 46.1 63.3 23.9 128.3 48.8 71.9 43.4 30.9 81.7 37.1 123.5 59.2 40.3 36.7 24.5 33.8 85.7 50.0 12.6 37.2 17.6 37.8 46.9 22.9 23.0 40.8 64.4 41.2 52.3 66.2 50.1 22.2 34.4 0.2 131.0 10.9 24.3 20.1 18.1 40.1 23.7 11.9 48.4 24.9 55.4 38.5 15.5 20.3 44.7 26.9 40.7 56.7 42.5 27.3 82.7 150.7 34.4 46.2 84.2 14.9 21.9 25.0 32.6 28.2 112.5 97.2 43.3 104.4 22.9 42.2 18.9 15.7 21.5 21.3 33.8 15.1 27.4 27.7 67.6 34.3 46.7 20.4 33.2 27.5 18.4 19.6 20.0 23.4 17.9 19.9 19.7 19.4 19.8 20.1 18.8 24.9 61.8 41.7 41.1 17.0 52.6 67.2 109.2 53.6 39.9 24.4 52.3 52.8 58.6 67.2 49.5 64.4 29.2 38.4 77.9 85.7 43.0 49.8 20.8 63.2 54.0 51.0 48.5 80.0 22.4 73.7 27.8 55.9 28.5 85.7 62.7 43.7 59.3 182.1 41.5 20.2 21.7 54.3 46.8 84.3 71.5 11.2 36.4 71.1 51.6 26.2 81.2 34.3 55.6 21.6 33.1 54.5 71.1 29.0 49.2 75.0 82.1 110.1 56.6 31.0 26.3 45.7 48.9 44.7 42.4 28.4 62.8 35.2 57.1 36.4 44.2 82.5 BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357028-32618899 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 272.0;Inhibitory neurons: 291.3;Oligodendrocytes: 361.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 9.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074409, HPA074738" Approved Supported "Golgi apparatus,Vesicles,Mitotic spindle" Yes No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: AB_2686710" "unprognostic (3.38e-2)" "unprognostic (8.13e-3)" "unprognostic (8.88e-2)" "unprognostic (7.06e-3)" "unprognostic (6.69e-3)" "unprognostic (9.01e-2)" "unprognostic (4.51e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.49e-2)" "unprognostic (4.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.30e-1)" "unprognostic (4.61e-1)" "unprognostic (7.32e-2)" "unprognostic (3.37e-1)" 4.6 4.7 3.1 6.7 9.7 11.3 8.9 13.9 5.7 7.7 6.3 7.6 5.0 6.8 5.2 5.3 6.2 5.8 4.9 4.6 3.7 7.6 8.9 5.4 9.6 6.4 5.5 12.0 14.7 10.9 2.9 6.9 7.3 6.2 7.5 15.5 5.5 5.9 6.1 6.7 5.4 6.1 4.4 8.5 7.1 6.8 5.6 14.7 11.4 8.8 9.7 7.2 3.1 16.3 21.7 17.8 16.1 7.9 14.9 19.1 11.3 10.8 14.1 11.0 11.3 14.2 5.7 23.6 7.3 19.7 13.2 10.1 22.9 15.1 13.9 18.8 10.5 31.2 11.3 10.7 7.9 32.4 11.9 12.4 6.9 18.0 16.2 10.1 17.7 5.4 25.6 10.0 11.9 9.3 15.5 7.5 11.7 9.2 10.5 14.6 26.6 8.2 9.2 23.4 11.7 18.4 18.6 10.8 8.2 12.5 6.4 11.5 28.7 13.0 13.3 9.1 15.3 13.9 20.0 30.6 10.1 15.1 8.7 9.7 0.9 0.6 1.3 0.7 1.8 0.8 1.0 1.2 0.7 1.8 1.1 1.4 1.5 1.6 1.5 1.6 1.0 0.5 3.1 9.7 13.9 5.7 4.6 3.7 6.4 5.5 7.3 4.4 5.6 16.3 53.9 32.1 30.5 239.3 74.8 46.0 28.6 34.7 41.5 60.8 40.0 23.4 45.8 38.6 42.7 36.8 191.8 35.0 93.4 70.1 1.9 26.9 45.9 39.3 58.0 49.8 32.5 34.3 272.0 31.2 22.0 39.7 68.3 63.1 29.9 52.1 45.7 47.5 29.8 69.0 291.3 43.3 26.4 54.7 60.0 17.6 45.4 59.1 23.2 202.4 67.2 34.9 64.9 231.8 361.3 34.3 30.3 59.0 70.9 46.4 48.5 22.6 30.6 88.2 39.5 56.0 49.1 53.7 46.2 49.7 54.8 38.0 72.4 52.8 45.3 44.0 BLCAP BC10 ENSG00000166619 "BLCAP apoptosis inducing factor" P62952 20 37492472-37527931 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 466.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 358.9" "Low region specificity" "Detected in all" HPA047390 Approved Nucleoli NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoli "HPA047390: AB_2680025" "unprognostic (1.05e-2)" "unprognostic (7.91e-3)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (7.08e-2)" "unprognostic (1.27e-2)" "unprognostic (3.49e-1)" "unprognostic (3.51e-1)" "unprognostic (4.45e-1)" "unprognostic (1.91e-3)" "unprognostic (4.91e-2)" "unprognostic (6.04e-2)" "unprognostic (1.04e-3)" "unprognostic (1.96e-2)" "unprognostic (7.62e-2)" "unprognostic (1.37e-2)" "prognostic favorable (7.28e-5)" 65.3 56.2 161.7 27.2 189.7 35.9 59.5 106.0 147.2 49.3 159.6 54.9 51.1 34.5 52.5 86.3 141.0 29.0 75.7 147.4 163.5 60.5 101.0 37.3 40.0 123.5 137.6 40.8 27.3 50.8 149.1 76.0 145.4 59.5 52.2 70.9 57.2 56.3 466.4 88.3 48.0 34.0 108.3 46.8 39.2 30.6 197.8 41.6 45.5 120.2 53.1 72.5 60.0 117.3 138.0 38.8 45.8 48.6 86.2 66.0 63.8 64.3 62.2 56.4 45.5 137.9 109.3 70.7 62.1 90.1 53.7 259.1 34.4 268.1 57.5 14.7 31.5 23.2 94.0 130.5 55.8 46.5 29.9 84.8 283.9 54.3 101.0 46.1 79.6 51.3 22.7 51.9 114.1 77.0 39.0 37.1 36.9 77.6 109.6 36.6 171.0 47.2 64.6 358.9 41.8 50.2 77.3 221.2 54.7 46.5 73.6 44.4 75.2 144.6 37.2 51.3 28.2 28.1 37.5 34.2 60.4 42.4 26.5 74.9 56.6 69.9 45.2 56.0 49.6 93.9 51.3 48.4 52.8 113.6 67.1 52.6 59.3 48.2 53.8 22.6 55.4 52.8 161.7 189.7 106.0 147.2 147.4 163.5 123.5 137.6 145.4 108.3 197.8 117.3 24.4 80.1 31.0 14.0 38.4 147.0 97.3 135.9 137.1 43.0 29.0 60.8 56.8 30.0 68.7 40.5 22.9 115.1 25.5 72.4 82.2 35.7 73.7 58.8 26.3 54.0 40.9 15.6 26.8 33.9 84.8 29.5 17.9 18.1 29.2 32.1 89.6 81.0 55.8 42.1 29.8 58.8 52.9 41.9 36.2 161.7 29.8 29.1 35.6 13.1 30.1 64.0 24.7 16.6 11.4 54.0 31.4 59.5 16.5 88.6 69.9 55.7 63.2 36.2 32.9 28.6 27.0 30.8 27.1 66.8 122.9 65.0 26.1 54.0 33.3 133.4 BLOC1S3 "BLOS3, HPS8" ENSG00000189114 "Biogenesis of lysosomal organelles complex 1 subunit 3" Q6QNY0 19 45178784-45216933 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050111, HPA070609" Approved Approved "Golgi apparatus" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" "HPA050111: AB_2681019, HPA070609: " "unprognostic (1.17e-1)" "unprognostic (3.97e-2)" "unprognostic (6.94e-3)" "unprognostic (6.26e-2)" "unprognostic (3.14e-1)" "unprognostic (3.04e-2)" "unprognostic (1.75e-2)" "unprognostic (2.30e-2)" "unprognostic (2.01e-1)" "unprognostic (9.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (3.89e-9)" "unprognostic (1.92e-2)" "unprognostic (1.93e-1)" "unprognostic (3.29e-1)" "prognostic favorable (6.86e-4)" 6.7 6.3 7.8 5.9 7.8 12.4 5.7 7.0 8.2 5.7 4.4 5.7 5.3 5.6 5.9 6.4 4.7 3.2 5.2 7.5 6.4 5.7 7.8 5.5 7.6 9.3 8.0 5.6 6.1 4.8 4.4 3.9 8.4 5.7 4.3 3.3 5.6 4.5 4.4 13.2 6.7 4.1 6.8 11.0 7.6 7.2 8.1 4.7 4.7 3.4 7.5 6.6 5.9 9.2 10.4 11.6 3.2 8.1 10.8 7.3 9.7 5.1 8.2 9.5 9.8 7.0 6.6 9.0 12.2 11.9 10.8 16.0 8.5 11.6 6.8 7.9 17.3 12.3 5.5 8.0 15.4 6.0 19.5 10.8 16.3 12.3 17.3 5.4 10.6 5.9 13.2 18.2 5.6 17.8 6.2 9.2 1.8 14.9 14.5 8.9 4.3 7.5 7.0 13.2 6.3 6.0 13.6 22.8 5.1 5.6 9.4 11.1 5.7 9.7 5.5 10.4 8.2 12.7 14.0 6.1 10.6 11.1 7.5 51.1 34.4 30.2 37.4 42.8 31.0 18.4 31.6 28.3 21.4 24.8 25.5 25.5 35.2 24.2 39.9 18.5 29.8 17.8 7.8 7.8 7.0 8.2 7.5 6.4 9.3 8.0 8.4 6.8 8.1 9.2 3.4 0.0 1.7 1.0 5.4 12.7 2.6 1.7 2.2 5.7 4.2 3.2 2.3 1.5 1.5 3.7 0.0 3.7 5.9 4.6 1.9 4.4 17.7 1.9 3.2 5.2 7.2 1.7 2.7 3.7 4.0 3.2 2.0 2.7 8.2 3.0 6.1 6.3 6.1 5.0 2.8 5.0 0.0 8.8 8.9 39.3 6.2 4.7 3.6 1.0 6.8 3.4 11.3 3.5 2.9 5.1 3.2 7.9 4.0 4.9 4.6 4.2 1.7 2.0 0.0 1.9 3.1 1.5 5.1 2.7 13.9 4.5 6.7 3.0 4.1 1.9 BLVRB "FLR, SDR43U1" ENSG00000090013 "Biliverdin reductase B" P30043 19 40447765-40465764 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 625.2" "Cell type enhanced" "Detected in all" "Erythroid cells: 3131.8;Hofbauer cells: 1099.2;Proximal enterocytes: 864.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 465.2" "Group enriched" "Detected in all" 7 "dendritic cells: 343.3;monocytes: 465.2" "Cell line enhanced" "Detected in many" "A549: 506.6;K-562: 506.8;OE19: 451.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041698, HPA041937" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "Nucleoplasm, Vesicles, Plasma membrane" "HPA041698: AB_10796781, HPA041937: AB_10794308" "unprognostic (1.86e-1)" "unprognostic (1.14e-2)" "unprognostic (4.23e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (1.20e-2)" "unprognostic (8.56e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" "unprognostic (2.02e-1)" "unprognostic (5.11e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" 115.7 76.8 46.6 48.2 46.9 625.2 93.8 49.4 61.0 86.2 52.1 78.5 75.1 59.0 20.5 188.8 69.3 50.9 125.6 44.5 48.0 103.1 266.2 102.8 58.9 56.0 48.6 66.7 73.2 46.1 25.2 52.1 58.5 74.3 30.3 5.5 89.4 42.2 210.4 83.9 72.2 31.7 49.8 166.7 138.4 10.2 52.3 27.5 64.5 94.1 25.3 81.0 96.5 53.4 227.9 506.6 7.3 77.7 73.7 70.2 57.3 28.0 88.7 39.3 75.4 103.4 203.8 74.3 212.3 56.3 126.8 73.1 30.4 64.6 10.5 123.8 20.0 114.9 73.4 62.4 169.8 1.6 32.2 69.2 119.4 52.4 34.2 40.1 41.8 27.4 506.8 137.0 51.0 359.2 6.1 7.2 1.9 451.4 133.8 54.0 23.4 120.3 50.9 146.5 0.4 10.5 84.5 224.5 84.4 13.2 221.5 17.6 39.2 99.4 103.9 156.4 15.9 71.7 92.1 28.5 259.1 46.2 39.0 45.5 465.2 18.0 29.2 220.9 27.0 58.2 24.3 24.5 343.3 37.5 24.7 19.3 58.4 27.4 117.7 75.8 37.3 259.4 46.6 46.9 49.4 61.0 44.5 48.0 56.0 48.6 58.5 49.8 52.3 53.4 74.6 221.2 164.5 9.4 34.4 129.4 348.5 337.9 103.6 11.2 93.8 143.0 130.5 164.5 184.2 97.5 6.2 84.9 39.5 343.6 266.1 234.2 10.0 56.5 46.3 51.1 44.9 3131.8 5.2 267.3 94.7 112.5 280.3 83.1 43.1 31.0 57.1 680.8 1099.2 10.1 5.1 223.5 158.7 627.7 165.4 23.6 124.2 286.7 144.1 13.1 219.8 88.0 32.0 2.0 5.6 260.4 464.0 94.0 25.7 229.7 864.3 488.3 139.1 13.5 32.9 65.4 146.0 2.6 4.0 160.3 130.4 74.7 34.5 34.7 191.0 260.5 BMP1 "BMP-1, PCOLC" ENSG00000168487 "Bone morphogenetic protein 1" P13497 8 22165140-22212326 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor, Hydrolase, Metalloprotease, Protease" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 69.3;Endometrial stromal cells: 52.8;Smooth muscle cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014572 Enhanced "Secreted to extracellular matrix" NA NA 9200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA014572: AB_1845390" "unprognostic (1.24e-1)" "unprognostic (8.01e-2)" "unprognostic (3.75e-2)" "unprognostic (5.89e-2)" "unprognostic (1.34e-2)" "unprognostic (6.76e-2)" "unprognostic (9.53e-2)" "unprognostic (2.64e-3)" "unprognostic (1.66e-1)" "unprognostic (9.75e-3)" "unprognostic (7.05e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.37e-9)" "unprognostic (2.11e-2)" "unprognostic (6.57e-2)" "unprognostic (1.50e-3)" "unprognostic (3.34e-2)" 11.7 17.4 3.8 6.3 4.6 1.4 9.0 4.7 4.4 15.6 4.9 8.1 4.8 12.7 3.9 7.0 11.8 9.8 5.9 4.3 3.9 7.7 14.7 8.3 1.7 5.0 4.1 5.9 4.4 3.4 3.4 27.3 4.1 9.6 5.3 0.6 3.7 6.1 3.4 6.2 5.9 14.4 4.3 5.0 4.3 2.4 4.2 1.5 10.0 3.1 1.8 10.4 10.3 4.4 15.2 20.4 7.4 30.2 47.8 41.8 23.2 54.1 50.1 33.8 27.6 5.1 27.4 3.7 32.0 56.9 18.9 51.2 5.1 27.8 6.5 3.6 6.9 6.7 24.5 7.9 31.7 2.9 14.3 49.8 26.5 25.2 11.4 78.3 31.4 5.2 7.1 10.6 19.6 4.6 1.4 3.0 4.7 17.0 8.3 6.4 8.2 15.2 26.7 4.1 2.8 10.6 52.5 3.1 13.4 20.4 5.0 8.3 41.4 17.0 18.4 32.3 23.9 4.0 2.2 0.6 23.8 10.1 28.0 0.0 0.4 0.0 0.6 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.2 0.0 0.1 3.8 4.6 4.7 4.4 4.3 3.9 5.0 4.1 4.1 4.3 4.2 4.4 12.5 6.4 69.3 5.5 0.8 6.2 5.2 22.6 4.0 2.6 5.0 6.1 4.9 2.8 6.7 5.5 0.0 3.3 3.2 31.9 0.0 25.1 0.7 3.1 52.8 14.1 3.0 0.8 3.5 8.2 9.5 28.7 1.1 5.7 15.2 13.9 14.6 20.1 4.3 1.7 2.7 6.2 0.0 3.4 6.1 1.1 10.2 5.4 10.6 4.7 1.0 2.2 3.1 6.6 6.7 15.3 18.6 10.9 2.8 4.7 13.2 4.1 2.2 1.1 26.3 6.4 43.7 1.5 4.0 6.5 5.3 24.4 3.3 34.2 10.7 8.0 BMP10 ENSG00000163217 "Bone morphogenetic protein 10" O95393 2 68860909-68871397 "Predicted secreted proteins" "Cell adhesion" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "heart muscle: 447.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "JURKAT: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 230000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.74e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 447.8 0.0 0.0 0.0 6.6 0.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767686-6780246 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal keratinocytes: 167.1;Distal enterocytes: 125.6;Suprabasal keratinocytes: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 31.6;HeLa: 19.6;hTERT-HME1: 17.8;RT4: 25.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA058610, CAB078457" Enhanced Vesicles "Secreted to blood" NA NA 24400 21000 "Cluster 19: Lung - Lung function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB078457: AB_2532532, HPA058610: AB_2683777" "unprognostic (2.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.12e-2)" "unprognostic (3.56e-2)" "unprognostic (1.94e-2)" "unprognostic (2.48e-1)" "unprognostic (3.70e-3)" "unprognostic (3.12e-3)" "unprognostic (8.51e-2)" "unprognostic (8.46e-2)" "unprognostic (2.53e-3)" "unprognostic (5.39e-3)" "unprognostic (7.81e-2)" "unprognostic (3.76e-1)" "unprognostic (2.77e-1)" "unprognostic (3.01e-2)" "unprognostic (7.49e-2)" 18.6 1.6 1.2 4.0 1.5 1.6 6.0 1.3 1.6 5.2 0.9 15.1 6.6 5.2 0.6 5.5 3.8 16.1 4.0 1.8 1.4 3.9 5.8 18.8 1.9 1.9 2.2 2.8 9.2 3.2 2.3 11.5 2.1 1.9 13.6 1.3 2.1 1.2 2.2 10.6 9.7 2.6 1.5 12.4 20.7 0.5 2.1 0.4 18.9 2.7 1.8 17.2 6.4 2.2 0.1 0.3 0.0 0.0 0.5 0.2 0.0 0.8 3.4 0.0 0.0 31.6 0.1 0.0 0.5 1.1 0.0 10.5 6.2 2.7 0.0 0.0 5.5 0.0 19.6 0.1 1.5 0.0 0.8 0.2 9.2 0.0 17.8 4.0 6.3 0.0 0.0 0.0 0.2 0.0 0.0 6.0 0.8 3.7 0.8 6.2 0.1 0.4 2.3 25.0 1.1 1.6 7.3 0.0 0.0 5.5 0.0 6.5 1.5 1.8 2.7 0.0 0.9 0.3 0.9 0.0 3.0 1.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 1.5 1.3 1.6 1.8 1.4 1.9 2.2 2.1 1.5 2.1 2.2 9.4 80.1 155.9 0.3 1.1 167.1 45.1 11.0 70.0 0.4 1.4 2.2 4.7 42.9 10.5 1.8 0.0 0.1 3.8 125.6 0.0 23.3 0.3 1.7 34.8 24.1 11.3 0.0 1.1 9.8 0.2 20.2 33.6 3.0 8.8 1.9 41.4 3.4 3.6 0.0 3.5 23.8 0.0 2.9 16.8 0.2 5.9 2.9 8.8 2.8 0.6 6.2 0.0 8.5 1.4 33.5 60.3 0.0 1.3 47.5 28.3 2.1 0.8 0.2 19.7 36.5 48.8 0.0 0.3 43.1 119.3 0.1 2.1 4.3 48.2 43.3 BMP3 ENSG00000152785 "Bone morphogenetic protein 3" P12645 4 81030708-81057627 "Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.3;lung: 5.5;urinary bladder: 9.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 32.2;Distal enterocytes: 68.9;Granulosa cells: 104.0;Paneth cells: 32.8;Proximal enterocytes: 25.2" "Group enriched" "Detected in some" 4 "lung cancer: 4.2;urothelial cancer: 7.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 10.3;Daudi: 16.3;RT4: 13.5;SK-BR-3: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (5.21e-3)" "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (3.36e-2)" "unprognostic (2.73e-3)" "unprognostic (9.11e-2)" "unprognostic (2.35e-1)" "unprognostic (1.94e-1)" "unprognostic (1.16e-4)" "unprognostic (2.26e-2)" "unprognostic (3.86e-1)" "unprognostic (1.11e-1)" "unprognostic (4.22e-2)" 1.5 0.4 0.3 0.3 0.2 0.8 1.2 0.2 0.3 0.4 0.1 9.3 3.2 0.0 0.1 0.0 0.9 2.0 0.0 0.1 0.6 0.1 0.0 5.5 0.3 0.7 0.7 2.5 0.0 0.0 0.0 0.0 0.5 0.2 6.8 0.5 1.3 0.0 0.0 0.3 7.2 0.5 0.6 0.0 1.1 0.1 1.4 0.0 0.0 0.6 1.5 9.5 0.2 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 0.0 0.0 0.0 1.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 13.5 0.1 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.3 0.1 0.6 0.7 0.7 0.5 0.6 1.4 0.0 0.0 3.2 32.2 0.0 0.2 0.1 0.5 0.7 0.0 2.2 0.1 0.0 1.3 0.0 15.1 0.0 0.0 0.0 0.0 68.9 0.0 0.0 0.0 0.9 0.1 0.3 0.0 0.0 1.6 0.0 0.0 2.1 0.0 0.0 0.0 104.0 0.0 0.0 0.0 0.0 5.6 5.0 6.1 0.0 1.2 0.0 0.9 0.2 0.0 1.0 0.0 0.2 0.0 0.0 0.1 0.2 32.8 0.0 0.0 0.5 25.2 0.1 9.4 0.1 0.0 0.3 1.2 0.2 0.3 0.0 0.4 0.0 0.0 0.1 14.1 3.8 BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 47.3;Fibroblasts: 65.2;Hepatic stellate cells: 52.8;Pancreatic endocrine cells: 40.1;Skeletal myocytes: 51.0;Syncytiotrophoblasts: 34.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 120.1;CAPAN-2: 298.6;Hep G2: 326.0;OE19: 219.1;SuSa: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" 14.0 13.4 3.0 6.1 3.2 0.1 13.4 7.0 4.5 21.0 32.4 25.6 17.0 8.9 2.5 12.9 9.7 14.4 16.3 3.1 2.8 9.0 4.2 13.4 9.6 3.6 3.3 23.8 3.4 2.7 4.7 44.4 3.9 21.9 28.9 2.7 10.5 18.7 11.5 15.3 19.2 9.0 3.2 6.5 23.8 2.0 3.9 3.4 8.5 17.7 4.2 27.4 23.5 4.7 15.6 40.0 2.1 1.8 0.5 0.4 0.6 7.9 34.0 20.1 15.5 120.1 298.6 0.0 97.2 0.1 2.2 73.2 8.6 1.0 10.7 4.1 5.9 0.2 8.3 326.0 19.4 0.0 1.0 0.0 2.8 9.5 0.5 61.1 59.3 6.8 0.0 0.3 9.7 6.9 5.3 0.3 13.9 219.1 3.4 0.2 10.5 0.3 28.5 1.3 0.1 0.3 0.0 1.1 0.9 168.2 38.8 1.5 2.9 0.6 87.1 0.3 1.4 0.2 0.1 1.0 0.1 0.1 4.3 0.0 0.6 0.0 0.1 1.1 0.0 0.0 0.9 0.2 0.1 0.0 1.3 0.4 0.0 0.0 1.9 0.0 0.0 0.3 3.0 3.2 7.0 4.5 3.1 2.8 3.6 3.3 3.9 3.2 3.9 4.7 7.6 9.6 7.3 1.0 0.6 27.5 4.0 16.1 47.3 0.3 8.0 10.4 5.7 14.3 6.0 5.5 0.0 29.3 0.1 1.0 3.9 5.5 2.5 0.7 18.9 18.2 0.0 2.7 1.3 0.2 18.9 65.2 0.5 0.7 1.3 0.9 52.8 2.0 3.7 0.0 0.4 5.3 2.0 0.6 5.9 1.0 10.5 0.4 3.6 1.9 0.0 0.5 0.0 1.0 0.3 40.1 4.0 1.5 0.1 2.3 0.6 2.4 5.8 1.5 0.0 51.0 10.5 1.4 2.2 7.5 17.5 34.8 1.0 1.4 4.0 1.4 BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 23.0;Hepatic stellate cells: 16.8;Inhibitory neurons: 22.8;Microglial cells: 74.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 37.0;HUVEC TERT2: 149.6;Karpas-707: 81.6;SiHa: 70.0;TIME: 74.3;U-266/84: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Approved Mitochondria "Secreted to blood" No No 4970000 46000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" 16.5 3.1 5.1 2.2 5.9 0.4 12.7 3.9 6.2 3.2 7.8 3.7 3.0 3.5 0.6 2.0 2.4 2.1 5.1 3.9 3.7 17.8 1.9 9.1 1.5 4.9 4.5 8.2 0.6 0.6 4.6 18.1 4.7 2.8 2.7 0.1 2.3 2.6 3.1 3.5 3.0 2.3 4.8 4.6 4.7 2.2 5.7 0.9 1.5 1.3 2.4 3.3 3.0 4.1 0.9 2.4 0.3 0.0 0.4 0.3 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 37.0 1.1 1.6 0.5 1.1 0.2 0.0 0.0 5.7 15.9 21.8 1.4 0.8 1.1 16.7 0.0 0.0 0.7 2.4 9.6 149.6 0.0 0.0 81.6 0.0 0.3 0.0 0.0 0.8 0.5 12.0 0.6 0.0 15.3 0.5 0.0 12.3 0.0 70.0 0.0 0.0 9.3 0.0 0.0 74.3 0.0 4.7 0.5 2.6 11.3 41.3 0.1 2.3 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 5.1 5.9 3.9 6.2 3.9 3.7 4.9 4.5 4.7 4.8 5.7 4.1 23.0 0.0 0.5 1.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3.5 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.8 0.2 8.9 0.0 0.0 7.8 0.0 0.1 2.0 0.0 2.0 0.0 1.5 16.8 0.6 0.3 0.0 22.8 0.0 0.0 0.8 2.1 4.2 0.0 1.5 1.8 74.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.8 0.3 0.0 0.0 0.3 0.0 0.0 4.7 0.4 0.1 1.3 0.1 0.1 0.3 0.4 0.4 0.0 0.0 BMP7 OP-1 ENSG00000101144 "Bone morphogenetic protein 7" P18075 20 57168753-57266641 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;choroid plexus: 43.8;thyroid gland: 45.9" "Cell type enhanced" "Detected in many" "Astrocytes: 74.1;Basal squamous epithelial cells: 51.8;Cytotrophoblasts: 137.4;Oligodendrocyte precursor cells: 74.4;Squamous epithelial cells: 44.2;Syncytiotrophoblasts: 56.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 172.1;MCF7: 202.3;OE19: 94.4;RPMI-8226: 77.8;SK-BR-3: 128.4;U-698: 237.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057757 Approved Nucleoplasm,Nucleoli,Vesicles "Secreted to blood" NA NA 248000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA057757: AB_2683518" "unprognostic (1.67e-1)" "unprognostic (9.72e-3)" "unprognostic (9.67e-2)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.62e-1)" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (4.63e-3)" "unprognostic (4.03e-2)" "unprognostic (1.09e-2)" "unprognostic (3.82e-2)" "unprognostic (4.30e-2)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (1.59e-1)" 1.5 6.5 33.1 1.9 34.6 0.0 1.3 37.2 27.9 8.5 43.8 2.9 2.2 1.2 17.2 23.9 9.5 0.4 13.8 35.6 28.5 6.3 0.0 1.6 1.0 36.2 36.3 0.2 0.5 0.0 2.7 25.7 34.7 5.9 1.7 5.3 3.9 9.2 0.3 22.5 1.9 0.3 32.8 0.6 3.6 0.7 39.7 3.8 45.9 0.0 2.1 6.8 13.0 42.8 0.3 0.7 23.4 5.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 20.0 6.8 172.1 41.3 0.0 8.7 48.3 5.2 0.0 0.0 0.4 17.2 0.1 0.0 0.0 0.0 0.0 5.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 202.3 0.0 0.1 12.3 94.4 0.0 0.1 0.1 77.8 0.0 0.2 0.4 17.8 5.5 128.4 0.5 15.2 0.9 0.4 0.4 0.1 10.9 0.0 0.1 0.2 0.3 237.6 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 34.6 37.2 27.9 35.6 28.5 36.2 36.3 34.7 32.8 39.7 42.8 0.6 6.4 2.2 74.1 0.4 13.8 13.4 12.9 51.8 4.7 0.9 4.6 15.1 0.0 4.2 1.8 0.0 137.4 0.1 0.2 0.0 0.0 5.3 1.7 2.4 1.2 2.4 0.0 0.9 0.0 21.0 13.5 2.0 2.5 21.6 0.1 0.0 0.0 11.0 1.7 4.7 1.5 6.1 0.0 1.9 4.9 0.3 0.4 3.6 2.8 0.1 38.4 0.0 74.4 8.7 0.0 0.3 0.4 2.5 6.6 0.2 2.2 1.9 2.4 0.0 1.3 0.8 1.8 3.4 44.2 9.7 56.9 0.9 0.7 1.5 18.1 BMP8A OP-2 ENSG00000183682 "Bone morphogenetic protein 8a" Q7Z5Y6 1 39491636-39529869 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 10 "thyroid gland: 91.6" "Group enriched" "Detected in some" 7 "Early spermatids: 42.2;Late spermatids: 164.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 7.0;HL-60: 5.8;U-2197: 22.2;U-266/70: 8.6;U-266/84: 7.9" HPA047254 Approved Vesicles "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA047254: " "unprognostic (9.62e-3)" "unprognostic (2.11e-2)" "unprognostic (7.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "unprognostic (2.00e-1)" "unprognostic (2.91e-3)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (5.33e-3)" "unprognostic (2.95e-9)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (2.28e-3)" "unprognostic (2.55e-2)" 0.5 0.8 2.1 1.4 3.7 1.3 0.2 2.7 3.7 2.3 0.0 1.0 1.4 3.3 3.8 0.5 3.4 1.2 1.1 2.7 1.6 0.9 0.3 0.4 1.8 7.0 3.5 2.9 2.6 0.8 0.5 0.4 4.7 1.2 0.6 1.8 1.2 3.5 2.6 1.7 2.1 5.1 4.1 1.6 0.9 3.3 3.2 5.8 91.6 0.1 0.5 0.9 0.5 9.4 0.4 1.1 0.8 0.5 0.1 0.1 0.6 0.2 0.0 0.0 0.0 1.2 0.2 0.3 0.1 0.1 0.1 1.0 0.0 0.0 0.0 0.8 1.0 0.1 2.0 0.1 7.0 5.8 0.2 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.3 3.7 0.0 1.6 0.2 1.2 2.0 0.2 0.1 0.8 0.1 3.2 0.0 0.3 1.2 0.2 0.3 0.3 0.5 1.0 1.0 1.1 0.2 0.1 0.8 22.2 0.1 8.6 7.9 0.5 0.2 0.7 0.1 0.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.3 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 2.1 3.7 2.7 3.7 2.7 1.6 7.0 3.5 4.7 4.1 3.2 9.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.2 0.0 0.2 0.1 0.0 0.0 5.7 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 164.4 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.7 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 BMP8B "BMP8, OP-2" ENSG00000116985 "Bone morphogenetic protein 8b" P34820 1 39757182-39788865 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.4" "Group enriched" "Detected in many" 5 "Early spermatids: 72.1;Late spermatids: 106.5;Plasma cells: 38.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "THP-1: 120.5;U-266/70: 33.7;U-266/84: 52.5;WM-115: 56.7" HPA047254 Approved Vesicles "Secreted to blood" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA047254: " "unprognostic (1.53e-3)" "unprognostic (7.29e-2)" "unprognostic (2.18e-1)" "unprognostic (6.64e-3)" "unprognostic (8.79e-2)" "unprognostic (3.44e-2)" "unprognostic (7.27e-2)" "unprognostic (7.56e-2)" "unprognostic (1.88e-1)" "unprognostic (7.41e-2)" "unprognostic (2.68e-1)" "unprognostic (4.72e-4)" "unprognostic (1.79e-2)" "unprognostic (3.15e-1)" "unprognostic (9.67e-2)" "unprognostic (8.68e-3)" "unprognostic (4.82e-1)" 1.7 5.6 2.1 1.5 2.0 0.8 0.9 1.1 5.3 2.1 0.1 3.8 5.4 1.5 3.3 1.0 1.3 0.8 1.0 2.8 1.8 0.9 0.6 1.3 0.7 13.4 3.5 0.8 7.0 1.8 2.7 1.5 3.3 2.4 2.7 0.5 1.7 2.5 0.6 2.0 4.1 0.7 2.8 1.5 1.8 2.2 2.6 0.4 4.7 1.6 0.7 1.6 2.1 4.7 2.7 4.5 0.3 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.8 5.4 0.1 1.8 0.0 0.7 0.4 4.2 0.0 0.0 1.0 5.8 4.9 3.6 0.3 0.1 0.6 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.6 18.1 0.2 3.7 0.1 2.5 0.3 2.8 1.8 2.7 15.9 5.7 4.0 2.7 13.0 3.4 4.3 0.3 13.4 0.9 3.1 120.5 0.0 0.1 0.3 1.1 0.2 33.7 52.5 2.0 0.0 3.7 56.7 0.2 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 2.1 2.0 1.1 5.3 2.8 1.8 13.4 3.5 3.3 2.8 2.6 4.7 0.0 0.0 1.8 0.0 3.5 0.4 0.6 0.2 0.0 0.5 1.1 0.8 1.2 0.0 0.8 0.0 0.0 0.0 0.9 13.5 0.0 1.0 72.1 1.1 0.6 0.4 1.2 0.0 0.4 3.4 0.0 1.7 1.1 2.3 0.0 0.3 0.4 0.0 0.4 0.0 0.3 2.0 0.0 0.0 2.7 106.5 1.2 0.8 5.4 0.0 0.7 0.1 0.0 8.0 1.8 2.2 2.2 0.7 38.9 0.4 5.0 0.0 0.4 0.5 0.0 1.8 3.4 0.8 0.4 0.4 0.0 0.0 0.7 0.1 1.2 0.8 BNC1 "BNC, HsT19447" ENSG00000169594 "Basonuclin 1" Q01954 15 83255903-83284714 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.0;esophagus: 12.5;testis: 30.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 88.6;Early spermatids: 45.5;Late spermatids: 103.4;Suprabasal keratinocytes: 58.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 25.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 51.1;HBEC3-KT: 116.6;hTCEpi: 128.1;hTERT-HME1: 123.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063183, HPA066947, HPA077428" Enhanced Nucleoplasm NA NA "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA063183: AB_2684957, HPA066947: AB_2685752, HPA077428: AB_2732345" "unprognostic (1.86e-3)" "unprognostic (1.08e-1)" "unprognostic (7.89e-3)" "unprognostic (5.55e-2)" "unprognostic (4.06e-2)" "unprognostic (2.47e-2)" "unprognostic (2.45e-2)" "unprognostic (7.91e-2)" "unprognostic (8.89e-4)" "unprognostic (6.94e-2)" "unprognostic (4.13e-1)" "unprognostic (3.85e-3)" "unprognostic (8.46e-3)" "unprognostic (2.20e-1)" "unprognostic (2.95e-3)" "unprognostic (1.01e-2)" 15.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 3.1 0.0 0.1 0.0 0.0 8.1 12.5 0.9 0.1 1.4 0.2 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.7 0.0 1.0 0.0 1.8 0.0 0.2 0.0 0.1 2.0 0.2 0.0 9.3 0.0 0.0 0.0 0.0 0.1 30.8 0.3 4.2 0.1 0.3 2.1 0.3 6.5 0.4 25.9 0.1 0.0 0.0 4.2 6.4 0.0 2.0 0.3 21.9 30.3 0.0 0.5 0.0 1.0 13.8 0.0 51.1 2.7 116.6 39.3 0.0 0.2 0.0 0.0 0.0 32.6 0.0 0.0 5.6 128.1 19.6 123.8 4.5 21.7 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 4.6 0.0 0.0 0.0 11.6 0.0 0.0 14.2 0.0 0.0 40.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.0 0.0 88.6 14.8 15.5 14.8 0.0 0.0 0.1 0.4 1.5 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 45.5 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 6.9 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 5.5 103.4 0.6 0.1 8.8 1.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.7 0.0 1.2 0.0 0.1 1.7 0.0 0.0 2.7 0.6 22.2 6.5 21.7 58.4 0.0 0.0 0.0 0.0 4.8 BNIP2 "BNIP-2, Nip2" ENSG00000140299 "BCL2 interacting protein 2" Q12982 15 59659146-59689534 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 131.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026843 Approved Supported Nucleoli,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol Nucleoli "HPA026843: AB_1845403" "unprognostic (3.41e-2)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "prognostic favorable (8.42e-4)" "unprognostic (6.70e-2)" "unprognostic (4.81e-2)" "unprognostic (2.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.44e-2)" "unprognostic (1.26e-1)" "unprognostic (4.72e-2)" "unprognostic (6.73e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (4.68e-3)" "unprognostic (1.81e-1)" "unprognostic (2.10e-2)" "unprognostic (1.01e-1)" 49.6 22.4 14.2 41.0 15.8 131.6 30.7 14.7 13.5 28.7 10.6 20.8 16.4 36.9 19.2 30.5 20.5 27.8 47.7 11.9 16.8 19.3 46.5 41.4 48.6 17.2 15.9 31.2 13.9 17.5 10.3 42.7 17.2 26.6 23.2 27.3 20.5 29.4 32.6 20.9 20.3 41.4 16.7 46.5 18.0 22.8 16.2 43.4 18.9 48.8 48.1 41.2 21.2 18.1 39.4 35.9 45.9 37.8 70.8 57.9 40.2 60.3 85.0 54.3 61.9 29.0 18.2 67.9 39.5 87.9 74.4 72.7 48.9 70.1 73.4 49.3 31.1 83.0 52.6 30.8 77.6 107.3 91.7 68.6 71.9 49.4 85.0 51.2 91.1 78.9 48.3 70.8 88.5 22.6 50.5 44.6 41.2 7.7 25.8 55.3 57.5 87.7 56.9 87.3 36.9 50.2 39.5 52.7 104.4 66.4 43.7 112.9 72.2 58.3 71.0 38.0 60.2 52.6 112.7 90.0 46.5 98.1 60.5 50.6 46.6 72.2 29.6 46.9 35.1 31.9 31.1 31.8 43.1 28.9 31.8 32.1 81.5 34.8 40.1 34.5 36.3 43.8 14.2 15.8 14.7 13.5 11.9 16.8 17.2 15.9 17.2 16.7 16.2 18.1 116.7 73.7 44.0 20.2 87.9 86.7 98.8 56.0 70.6 32.5 35.3 29.6 81.9 28.6 43.0 14.7 47.9 64.0 82.6 31.3 37.2 31.5 9.0 41.8 44.5 105.6 15.5 57.7 15.4 26.8 76.8 68.0 46.9 65.8 96.4 31.0 87.8 49.6 91.7 50.5 17.5 24.3 32.6 115.6 106.7 6.1 43.5 125.6 51.6 25.3 120.8 55.3 64.9 20.6 28.2 36.9 22.1 57.2 63.1 75.1 20.0 16.6 45.4 50.2 78.9 56.2 68.1 28.8 32.2 64.4 92.5 193.9 73.5 42.3 19.4 136.8 BOC CDON2 ENSG00000144857 "BOC cell adhesion associated, oncogene regulated" Q9BWV1 3 113211003-113287459 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Basal squamous epithelial cells: 112.1;Fibroblasts: 55.4;Leydig cells: 84.8;Peritubular cells: 47.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 79.2;ASC diff: 113.6;BJ hTERT+: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025806 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" "Intracellular and membrane" NA No 7900000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies, Plasma membrane" Nucleoplasm "CAB025806: " "unprognostic (6.89e-3)" "unprognostic (1.34e-2)" "unprognostic (2.62e-3)" "unprognostic (1.03e-2)" "unprognostic (5.03e-3)" "prognostic favorable (4.89e-4)" "unprognostic (8.66e-5)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (4.78e-3)" "unprognostic (3.42e-2)" "unprognostic (1.10e-1)" "unprognostic (3.65e-3)" "unprognostic (4.94e-3)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.18e-5)" 41.6 5.8 15.8 10.4 15.5 0.2 29.8 13.1 12.1 26.0 33.2 49.1 4.9 46.6 10.1 24.9 63.2 19.3 14.3 17.1 15.2 9.7 1.0 6.6 3.6 53.2 30.1 35.2 16.1 2.7 20.8 2.2 23.2 33.8 4.6 3.2 23.8 21.3 6.3 34.9 18.3 32.6 32.3 4.6 19.0 5.0 26.3 5.7 24.6 9.0 3.1 32.5 25.8 23.4 0.0 7.6 27.6 79.2 113.6 6.0 0.9 12.8 41.9 3.2 2.7 0.0 0.0 0.1 7.8 21.8 1.7 0.0 5.6 2.7 1.1 0.0 3.4 0.0 2.3 0.0 0.6 0.3 0.2 19.7 1.8 1.7 0.2 25.7 0.0 0.0 0.1 0.0 0.6 2.1 0.2 1.4 7.0 0.0 6.9 0.2 12.3 0.0 0.7 0.1 8.2 11.7 0.1 0.5 0.3 8.1 3.4 0.4 0.0 4.5 7.3 0.1 4.2 0.0 0.0 0.0 9.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 15.5 13.1 12.1 17.1 15.2 53.2 30.1 23.2 32.3 26.3 23.4 9.6 0.0 0.5 71.8 0.0 21.2 3.1 3.6 112.1 0.6 3.7 17.3 1.1 1.5 0.7 5.5 0.0 4.8 0.2 0.0 0.0 0.1 1.4 12.6 10.5 5.6 1.8 0.0 8.8 0.0 4.3 55.4 0.5 11.7 0.0 5.7 3.3 0.1 0.8 0.0 2.5 0.0 0.0 0.3 5.5 3.3 84.8 1.0 10.6 6.5 0.0 12.2 0.0 24.1 0.7 0.3 0.0 47.8 0.6 3.3 0.0 0.0 0.3 0.5 0.0 18.0 13.5 1.5 3.2 11.5 11.1 1.9 0.8 1.1 0.0 0.9 BOD1 FAM44B ENSG00000145919 "Biorientation of chromosomes in cell division 1" Q96IK1 5 173607145-173616659 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA036293 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "HPA036293: AB_10673127" "unprognostic (2.85e-2)" "unprognostic (1.48e-1)" "unprognostic (4.04e-3)" "unprognostic (1.04e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (2.49e-6)" "unprognostic (1.21e-1)" "unprognostic (7.66e-3)" "unprognostic (8.52e-2)" "unprognostic (2.34e-2)" "unprognostic (9.29e-2)" "unprognostic (1.00e-1)" "unprognostic (3.61e-1)" "unprognostic (1.93e-1)" "unprognostic (1.07e-2)" "unprognostic (2.51e-1)" 42.2 41.8 34.1 19.2 36.2 7.6 44.0 33.9 42.6 43.6 35.2 40.4 22.6 37.9 37.9 25.3 35.4 22.8 45.4 33.8 35.7 33.9 29.6 29.2 22.2 35.0 35.0 53.8 48.9 34.8 34.6 34.5 34.4 34.7 24.6 45.5 27.4 29.4 111.7 38.0 24.1 27.9 34.8 25.9 34.5 40.3 36.8 18.8 50.0 78.0 17.7 39.9 35.3 39.6 57.9 60.8 113.5 117.8 98.1 74.8 88.1 50.7 102.1 82.1 132.3 116.0 61.7 39.3 123.4 77.0 201.5 45.8 91.1 124.6 108.6 34.7 72.2 11.5 51.0 106.5 115.8 25.7 15.6 73.9 101.7 54.3 208.6 60.5 69.2 24.6 24.3 25.7 70.2 120.4 38.7 31.1 94.7 64.4 107.0 35.4 58.5 34.5 34.1 55.9 142.2 59.0 38.7 42.8 163.6 95.5 125.7 29.6 53.0 92.1 56.7 73.1 78.5 29.7 34.9 47.6 49.0 37.8 71.5 0.0 2.0 5.6 2.7 2.4 2.1 2.3 2.0 2.4 2.8 2.4 3.8 2.9 0.4 3.5 1.1 3.5 2.3 1.1 34.1 36.2 33.9 42.6 33.8 35.7 35.0 35.0 34.4 34.8 36.8 39.6 56.6 32.1 20.3 7.5 24.2 72.8 50.2 15.0 27.9 41.0 47.7 46.0 41.8 28.6 22.0 9.2 12.5 67.1 20.8 10.2 60.7 38.3 116.0 24.6 52.6 47.1 23.4 7.2 7.0 26.9 83.5 58.5 23.9 28.5 8.8 93.9 28.2 16.6 27.8 53.8 7.9 26.2 20.3 12.0 33.1 141.1 73.0 16.8 33.8 4.7 23.9 61.9 25.7 8.5 10.1 21.9 13.4 59.8 17.4 84.1 19.1 50.4 14.8 39.7 13.1 50.7 46.2 89.7 69.5 30.9 83.5 59.4 19.0 165.5 37.5 47.9 BPHL "Bph-rp, MCNAA, VACVase" ENSG00000137274 "Biphenyl hydrolase like" Q86WA6 6 3118374-3153578 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 110.4;liver: 84.8" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 99.7;Proximal tubular cells: 336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036752, HPA036753" Enhanced Approved Mitochondria NA NA 14000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036752: AB_10673662, HPA036753: AB_2675291" "unprognostic (2.93e-1)" "unprognostic (1.29e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-1)" "unprognostic (3.72e-3)" "unprognostic (1.84e-1)" "unprognostic (8.65e-2)" "unprognostic (3.14e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.97e-4)" "unprognostic (4.59e-2)" "unprognostic (9.46e-3)" "prognostic favorable (5.16e-7)" "unprognostic (1.60e-2)" "unprognostic (1.51e-2)" "unprognostic (6.98e-2)" "unprognostic (5.20e-2)" 24.1 15.3 9.4 3.9 9.8 3.5 11.2 9.5 14.5 9.3 11.8 10.6 33.8 7.0 28.8 13.2 11.1 8.9 11.6 10.1 10.8 110.4 84.8 5.2 4.4 9.8 10.2 6.5 11.5 10.8 12.7 5.0 10.7 6.8 9.4 4.2 11.3 4.7 15.5 11.2 32.8 5.8 8.6 3.9 10.0 5.0 9.8 4.8 5.5 12.5 5.9 9.0 9.1 10.8 12.0 13.8 26.8 30.6 22.5 16.2 10.2 7.1 8.7 8.6 11.4 12.4 15.3 18.6 19.7 9.2 21.4 22.1 11.7 8.0 7.6 24.8 10.5 2.7 5.4 21.8 7.9 6.3 1.8 16.9 14.1 6.3 6.0 17.7 15.5 18.8 7.2 3.0 19.9 18.2 14.8 8.3 22.5 21.1 21.9 16.1 17.7 27.9 19.7 30.3 31.7 23.3 13.2 9.0 58.4 39.4 25.6 2.2 7.7 12.5 3.4 13.1 4.9 8.6 27.8 20.4 3.5 4.0 18.4 13.6 9.8 0.0 8.2 12.9 10.9 17.5 9.7 8.4 15.3 12.8 9.1 12.7 0.6 14.6 7.8 8.4 5.4 7.5 9.4 9.8 9.5 14.5 10.1 10.8 9.8 10.2 10.7 8.6 9.8 10.8 15.9 6.4 9.3 11.1 8.2 8.9 8.6 26.0 10.8 11.1 15.1 19.0 4.8 31.5 19.3 16.5 20.9 28.6 5.6 13.6 70.5 28.1 0.5 13.6 14.0 9.1 16.1 6.9 9.3 13.5 32.2 12.2 11.2 8.2 2.5 31.8 6.1 70.9 23.7 16.8 12.8 14.9 38.7 2.2 8.3 1.6 14.9 8.0 32.0 10.3 13.9 12.2 7.2 9.0 4.7 19.6 14.8 13.9 4.5 8.4 99.7 336.3 38.2 6.9 6.6 19.0 12.5 6.8 20.6 13.9 9.2 14.0 7.6 32.9 19.0 8.1 BPI BPIFD1 ENSG00000101425 "Bactericidal permeability increasing protein" P17213 20 38304150-38337505 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "bone marrow: 1503.7" "Group enriched" "Detected in some" 8 "Early spermatids: 201.8;Late spermatids: 220.6;Proximal tubular cells: 99.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "classical monocyte: 14.5;neutrophil: 7.1" "Group enriched" "Detected in many" 17 "granulocytes: 7.1;monocytes: 14.5" "Cell line enhanced" "Detected in single" "HL-60: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA061284 Enhanced "Secreted to blood" NA NA 7290000 78000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA061284: AB_2684465" "unprognostic (9.30e-4)" "unprognostic (5.49e-2)" "unprognostic (1.97e-1)" "unprognostic (2.26e-1)" "unprognostic (1.44e-1)" "unprognostic (1.56e-1)" "unprognostic (4.50e-2)" "unprognostic (1.98e-1)" "unprognostic (3.07e-2)" "unprognostic (1.14e-1)" "unprognostic (2.60e-2)" "unprognostic (1.50e-1)" "unprognostic (8.83e-6)" "unprognostic (2.66e-4)" "unprognostic (9.29e-2)" "unprognostic (2.32e-2)" "unprognostic (9.47e-3)" 0.5 0.2 0.1 0.1 0.2 1503.7 0.6 0.1 0.4 2.6 0.2 0.2 0.0 0.7 1.0 0.1 0.4 0.5 0.5 0.1 0.2 3.4 0.8 3.7 0.3 0.2 0.2 1.7 0.0 0.0 0.6 0.5 0.2 0.4 0.0 0.0 1.4 1.2 0.1 1.8 0.1 0.2 0.2 13.0 0.1 17.1 0.2 3.7 0.2 0.2 0.2 0.2 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 14.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.1 0.0 0.6 0.0 0.0 9.8 0.1 0.2 0.1 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.0 0.0 1.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.3 0.3 0.4 0.0 0.4 3.7 0.0 0.0 0.0 0.0 9.8 0.0 201.8 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.7 20.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 220.6 17.7 1.3 1.8 0.0 7.1 0.0 1.0 0.0 0.0 0.0 0.0 18.4 0.0 0.0 0.0 99.7 0.3 0.0 0.0 0.2 0.4 2.1 1.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 BPIFA1 "bA49G10.5, LUNX, PLUNC, SPLUNC1" ENSG00000198183 "BPI fold containing family A member 1" Q9NP55 20 33235995-33243311 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 6.2;lung: 18.3;pituitary gland: 12.1" "Cell type enriched" "Detected in some" 6 "Club cells: 1205.8" "Cancer enriched" "Detected in many" 27 "lung cancer: 262.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "cerebellum: 2.0" "Not detected" "Not detected" CAB025669 Supported "Secreted in other tissues" NA NA 1200000 "Cluster 19: Lung - Lung function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025669: " "unprognostic (1.06e-1)" "unprognostic (1.53e-1)" "unprognostic (3.65e-1)" "unprognostic (1.80e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.7 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 0.0 0.0 129.5 0.0 0.0 0.0 0.0 0.0 0.0 1205.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 126.1 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.0 0.0 0.0 0.0 80.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 BPIFA2 "bA49G10.1, C20orf70, PSP, SPLUNC2" ENSG00000131050 "BPI fold containing family A member 2" Q96DR5 20 33161768-33181412 "Predicted secreted proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1619 "salivary gland: 6860.0" "Cell type enriched" "Detected in some" 4 "Ionocytes: 649.0" "Group enriched" "Detected in some" 4 "lung cancer: 2.6;pancreatic cancer: 2.9;stomach cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 1.0;RT4: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA044006 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA044006: AB_10963580" "unprognostic (9.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (3.56e-2)" "unprognostic (3.03e-2)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (1.04e-1)" "unprognostic (6.14e-4)" 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.1 0.0 0.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.8 3.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6860.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 49.3 0.0 0.0 0.0 0.0 0.2 0.0 145.2 3.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 649.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 17.3 0.0 0.0 0.0 8.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 BPIFA3 "bA49G10.4, C20orf71, SPLUNC3" ENSG00000131059 "BPI fold containing family A member 3" Q9BQP9 20 33217310-33227806 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 537 "testis: 53.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 3057.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062708 Enhanced "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA062708: AB_2684843" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 736.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3057.9 14.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 18.2 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BPIFB1 "bA49G10.6, C20orf114, dJ1187J4.1, LPLUNC1, MGC14597, VEMSGP" ENSG00000125999 "BPI fold containing family B member 1" Q8TDL5 20 33273480-33309871 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 566.8;salivary gland: 271.3;stomach 1: 512.5" "Cell type enriched" "Detected in many" 5 "Club cells: 5748.4" "Cancer enhanced" "Detected in many" "stomach cancer: 75.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;OE19: 3.8;RT4: 2.2;SK-BR-3: 4.3" "Region enriched" "Detected in single" 6 "olfactory bulb: 4.8" "Low region specificity" "Detected in many" HPA024256 Enhanced "Secreted in other tissues" NA NA 2700000 "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA024256: AB_1845664" "unprognostic (2.42e-1)" "unprognostic (5.41e-2)" "unprognostic (3.67e-2)" "unprognostic (3.09e-1)" "unprognostic (6.72e-2)" "unprognostic (3.43e-2)" "unprognostic (9.37e-3)" "unprognostic (1.14e-1)" "unprognostic (2.82e-1)" "unprognostic (4.00e-2)" "unprognostic (9.01e-2)" "unprognostic (1.36e-7)" "unprognostic (3.30e-1)" "unprognostic (5.03e-2)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" 0.1 0.1 0.0 0.0 0.3 0.0 0.9 0.0 0.1 566.8 0.0 0.5 25.6 0.0 0.0 47.1 0.1 3.4 0.0 0.4 0.0 0.0 0.1 112.5 0.2 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 1.2 0.0 0.0 271.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 512.5 3.5 0.0 0.2 0.0 0.0 1.2 8.3 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 3.8 0.0 0.4 0.0 0.1 0.0 2.2 0.0 0.0 0.0 4.3 0.0 0.0 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 22.7 0.0 0.0 1.3 1.4 614.0 0.0 0.0 2.0 1.3 0.4 2.8 5748.4 0.0 0.0 0.2 0.0 0.0 0.0 0.3 63.6 0.4 0.1 1.1 0.0 0.0 0.2 0.2 0.1 3.0 31.1 0.6 3.8 0.0 0.4 0.1 0.2 0.0 0.1 0.0 1021.3 0.0 1.9 82.9 0.3 1.5 1.8 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.7 0.0 2.0 0.0 0.0 1027.4 0.0 0.0 0.4 305.5 5.8 0.8 11.6 0.4 0.1 1.0 0.0 0.0 95.9 BPIFB2 "BPIL1, C20orf184, dJ726C3.2, LPLUNC2" ENSG00000078898 "BPI fold containing family B member 2" Q8N4F0 20 33007704-33023703 "Plasma proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "salivary gland: 2294.3" "Group enriched" "Detected in some" 4 "Breast glandular cells: 6.1;Breast myoepithelial cells: 9.1;Early spermatids: 4.8;Late spermatids: 9.3;Prostatic glandular cells: 7.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 582 "Hep G2: 232.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049491, HPA060121" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 36000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA049491: AB_2680792, HPA060121: AB_2684207" "unprognostic (1.94e-1)" "prognostic favorable (1.97e-5)" "unprognostic (2.24e-4)" "unprognostic (9.48e-2)" "unprognostic (9.81e-2)" "unprognostic (2.02e-3)" "unprognostic (1.72e-2)" "unprognostic (2.71e-1)" "unprognostic (9.28e-2)" "unprognostic (5.35e-1)" "unprognostic (8.19e-2)" 0.4 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.0 99.8 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 1.8 0.0 0.0 2294.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.1 9.1 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 BPIFB3 "C20orf185, dJ726C3.4, LPLUNC3, RYA3" ENSG00000186190 "BPI fold containing family B member 3" P59826 20 33055424-33073628 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.9;Late spermatids: 1.8" "Cancer enriched" "Detected in single" 7 "ovarian cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "HEL: 3.7;HMC-1: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA045741 Uncertain "Secreted in other tissues" NA NA "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "HPA045741: AB_2679439" "unprognostic (4.33e-2)" "unprognostic (1.06e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BPIFB4 "C20orf186, dJ726C3.5, LPLUNC4" ENSG00000186191 "BPI fold containing family B member 4" P59827 20 33079644-33111751 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "pituitary gland: 8.4" "Cell type enhanced" "Detected in single" "Basal respiratory cells: 2.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HSkMC: 2.3;U-2 OS: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA047388 Approved "Actin filaments,Cytosol" "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Actin filaments, Cytosol" "HPA047388: " "unprognostic (1.32e-1)" "unprognostic (1.16e-1)" "unprognostic (1.61e-1)" "unprognostic (2.75e-2)" "unprognostic (1.31e-3)" "unprognostic (4.70e-2)" "unprognostic (3.42e-2)" "unprognostic (2.03e-1)" "unprognostic (3.98e-4)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" "unprognostic (8.97e-2)" 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 BPIFB6 "BPIL3, LPLUNC6" ENSG00000167104 "BPI fold containing family B member 6" Q8NFQ5 20 33031648-33044047 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "salivary gland: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043057 Uncertain "Secreted in other tissues" NA NA "Cluster 24: Salivary gland - Salivary secretion" "HPA043057: AB_10796683" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BPIFC "BPIL2, dJ149A16.7" ENSG00000184459 "BPI fold containing family C" Q8NFQ6 22 32413847-32464484 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 63.6" "Cell type enhanced" "Detected in some" "Early spermatids: 22.8;Late spermatids: 9.8;Suprabasal keratinocytes: 4.7" "Group enriched" "Detected in some" 11 "head and neck cancer: 1.6;melanoma: 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 22 "basophil: 2.1" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.1" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.74e-1)" "unprognostic (3.48e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (2.58e-1)" "unprognostic (3.48e-2)" "unprognostic (2.74e-1)" "unprognostic (2.58e-1)" "unprognostic (2.76e-3)" "unprognostic (1.41e-2)" "unprognostic (2.80e-1)" 0.1 0.0 0.2 0.0 0.1 0.0 3.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 63.6 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.0 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 9.8 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 4.7 0.0 0.0 0.0 0.0 0.0 BRD3 "KIAA0043, ORFX, RING3L" ENSG00000169925 "Bromodomain containing 3" Q15059 9 134030305-134068535 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 178.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051830 Approved Approved "Nuclear bodies" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "HPA051830: AB_2681627" "unprognostic (3.53e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (1.90e-1)" "unprognostic (6.20e-2)" "unprognostic (2.60e-2)" "unprognostic (2.98e-2)" "unprognostic (3.48e-2)" "unprognostic (1.11e-2)" "unprognostic (6.75e-2)" "unprognostic (2.79e-1)" "unprognostic (1.98e-1)" "prognostic favorable (2.71e-7)" "unprognostic (1.00e-1)" "unprognostic (4.71e-2)" "unprognostic (2.57e-2)" "unprognostic (1.42e-1)" 10.6 10.3 14.2 7.3 14.7 8.2 10.2 13.0 13.6 12.9 6.4 16.1 7.9 14.6 9.4 8.6 12.5 6.9 9.5 11.6 14.6 7.8 11.0 9.2 7.5 13.9 12.6 11.6 10.7 10.1 9.2 9.0 11.7 11.8 5.6 10.6 9.6 11.6 19.3 12.6 9.6 9.0 10.4 12.4 9.9 13.0 13.5 13.4 11.8 11.5 5.8 11.8 10.3 15.9 8.5 25.3 31.4 24.6 17.1 13.8 28.7 8.4 9.5 9.2 9.3 21.2 13.7 3.2 8.7 7.7 10.4 28.7 29.4 11.7 7.2 20.1 16.5 18.2 29.1 24.1 15.3 24.1 15.7 14.8 14.1 10.6 12.0 14.9 15.2 30.0 16.7 9.3 9.5 28.4 44.9 32.2 42.0 21.9 19.2 32.8 45.3 16.1 13.1 8.9 45.8 42.3 37.7 14.1 10.1 18.7 20.3 39.6 19.5 22.3 12.3 14.6 7.6 5.0 5.6 3.0 11.2 16.4 15.1 6.6 12.9 15.8 11.4 10.1 9.6 6.9 9.1 10.2 12.9 6.7 8.6 9.1 15.0 16.3 8.6 17.1 4.6 9.4 14.2 14.7 13.0 13.6 11.6 14.6 13.9 12.6 11.7 10.4 13.5 15.9 27.6 32.1 21.9 13.1 18.3 32.4 21.2 19.8 42.1 60.9 32.8 24.3 24.3 28.6 25.7 23.9 37.5 26.0 31.8 22.6 19.6 42.7 49.2 22.9 37.9 32.1 54.0 70.1 13.4 24.4 20.5 32.4 21.9 25.3 15.9 53.2 35.7 34.0 18.7 57.2 16.8 26.6 14.2 27.9 22.8 20.7 57.2 33.6 23.2 10.3 33.6 45.6 30.9 12.5 19.3 27.7 21.4 67.4 9.1 51.0 19.2 15.7 20.1 58.0 59.2 55.8 40.0 20.7 53.1 31.9 35.7 32.7 26.4 178.7 30.8 22.3 BRF1 "BRF, GTF3B, hBRF, TAF3B2, TAF3C, TFIIIB90" ENSG00000185024 "BRF1 RNA polymerase III transcription initiation factor subunit" Q92994 14 105209286-105315589 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051918, HPA074990" Approved Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies" "HPA051918: AB_2681663, HPA074990: " "unprognostic (1.98e-1)" "unprognostic (4.45e-2)" "unprognostic (1.46e-2)" "unprognostic (2.51e-2)" "unprognostic (1.07e-1)" "unprognostic (7.52e-2)" "unprognostic (1.52e-4)" "unprognostic (2.67e-2)" "unprognostic (3.25e-1)" "unprognostic (2.26e-1)" "prognostic favorable (7.25e-6)" "unprognostic (8.83e-2)" "prognostic favorable (1.13e-4)" "unprognostic (1.85e-1)" "unprognostic (2.70e-1)" "unprognostic (5.39e-2)" "unprognostic (2.52e-1)" 10.5 11.4 19.7 5.5 22.2 6.5 10.5 23.1 23.6 12.5 12.9 11.1 7.6 12.1 4.2 10.4 12.8 6.0 12.2 17.1 19.2 11.6 13.1 8.4 8.1 31.8 24.9 13.0 15.1 10.3 20.4 6.0 29.7 12.0 4.2 7.5 10.1 6.3 17.7 11.2 10.3 4.6 18.7 12.6 11.2 14.6 25.4 7.3 10.5 9.6 5.8 11.5 9.9 37.4 12.6 28.0 11.8 25.3 10.3 11.4 11.9 17.4 11.2 15.4 12.2 20.2 18.8 9.4 16.9 12.0 7.5 24.2 14.4 11.7 8.4 25.2 14.2 11.5 15.1 9.9 11.5 13.7 24.3 11.3 10.1 9.3 11.5 7.8 11.3 19.7 13.1 7.5 7.6 40.9 16.2 17.1 8.6 20.7 27.7 28.2 8.1 9.6 7.6 29.9 37.5 27.8 18.4 14.0 16.0 5.4 33.4 18.9 16.8 12.1 9.6 22.7 14.2 13.8 11.5 8.9 14.5 11.3 16.9 0.4 1.2 2.0 1.6 1.0 1.1 1.5 1.1 1.6 1.2 1.4 1.4 1.3 0.5 2.5 4.0 3.1 1.6 1.6 19.7 22.2 23.1 23.6 17.1 19.2 31.8 24.9 29.7 18.7 25.4 37.4 11.5 3.2 5.9 17.6 11.4 7.5 7.1 4.5 8.6 18.8 10.7 9.0 8.5 2.8 6.3 3.7 16.7 11.4 15.5 16.2 3.9 5.8 2.3 26.5 10.9 9.5 9.6 6.3 18.3 7.1 8.9 7.7 14.8 16.5 2.5 16.0 8.9 11.3 7.2 30.3 20.8 11.7 4.1 6.7 10.3 1.4 6.5 7.8 8.8 10.3 5.3 7.1 4.1 15.1 34.2 4.8 6.5 4.5 13.4 7.7 8.9 6.1 12.4 20.0 0.0 9.6 8.2 9.2 12.7 7.7 8.8 9.3 11.6 13.2 12.5 5.1 BRICD5 "C16orf79, MGC21830" ENSG00000182685 "BRICHOS domain containing 5" Q6PL45 16 2209253-2211950 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.8;Cone photoreceptor cells: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 18.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.1" HPA063522 Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Actin filaments" Nucleoplasm "HPA063522: AB_2685029" "prognostic favorable (9.74e-4)" "unprognostic (7.12e-3)" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (1.18e-1)" "unprognostic (1.93e-3)" "unprognostic (2.02e-1)" "unprognostic (4.62e-2)" "unprognostic (4.34e-3)" "unprognostic (7.56e-2)" "prognostic favorable (7.01e-4)" "unprognostic (9.84e-3)" "unprognostic (2.65e-2)" "unprognostic (9.79e-2)" "unprognostic (2.88e-1)" "unprognostic (3.57e-1)" "prognostic favorable (8.06e-5)" 5.0 6.6 9.7 3.3 10.4 3.0 5.8 25.5 18.7 9.3 6.1 9.7 4.7 8.2 1.3 4.2 8.6 1.9 15.9 9.3 9.9 19.1 7.9 10.2 4.3 11.4 9.0 7.0 5.5 1.4 14.3 2.6 10.8 11.0 0.6 4.6 5.9 2.5 11.1 4.7 10.4 1.2 6.8 16.7 7.4 17.5 10.1 2.2 23.3 1.6 1.3 8.9 6.0 10.6 3.3 6.3 7.5 4.7 1.2 1.1 15.6 3.1 0.4 1.8 2.6 8.3 8.0 1.6 2.0 0.6 1.9 8.6 1.1 1.1 1.1 6.0 3.4 2.1 18.4 2.0 0.7 0.7 4.7 1.6 2.3 2.5 0.6 2.2 0.9 6.9 2.3 4.3 0.4 8.6 5.1 12.8 8.4 0.7 3.7 16.8 5.6 5.9 2.0 2.5 5.8 5.5 2.9 3.6 3.1 3.0 3.4 4.4 2.3 8.0 6.6 6.7 2.7 13.5 6.6 4.7 1.5 5.0 3.8 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 9.7 10.4 25.5 18.7 9.3 9.9 11.4 9.0 10.8 6.8 10.1 10.6 2.4 3.2 4.4 10.4 1.6 0.4 0.4 1.1 0.0 11.8 1.8 1.5 0.5 0.0 0.7 5.5 25.0 2.0 1.3 2.4 0.0 0.9 2.4 0.9 1.1 2.2 1.2 2.1 5.7 0.6 0.9 1.1 4.1 1.5 4.5 4.8 1.1 1.2 1.2 5.0 5.5 1.0 2.0 1.9 2.0 10.2 1.2 2.8 1.8 2.8 2.5 4.5 4.1 3.5 5.2 1.0 0.8 2.6 1.5 0.9 1.9 0.6 3.4 10.9 0.0 1.2 1.3 4.0 1.9 0.4 1.1 0.8 1.7 1.6 3.1 0.3 BRINP1 "DBC1, DBCCR1, FAM5A" ENSG00000078725 "BMP/retinoic acid inducible neural specific 1" O60477 9 119153458-119369435 "Predicted intracellular proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 43.5" "Group enriched" "Detected in some" 8 "Astrocytes: 178.9;Excitatory neurons: 285.7;Inhibitory neurons: 163.4;Oligodendrocyte precursor cells: 204.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 8.6;NTERA-2: 17.0;SCLC-21H: 7.4;SH-SY5Y: 3.2;SuSa: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038828 Approved Uncertain Microtubules "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Microtubules "HPA038828: AB_10670909" "unprognostic (8.60e-5)" "unprognostic (2.31e-2)" "unprognostic (1.24e-1)" "unprognostic (5.09e-5)" "unprognostic (1.12e-1)" "unprognostic (1.14e-2)" "unprognostic (1.37e-1)" "unprognostic (2.98e-1)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (2.28e-4)" "unprognostic (1.51e-2)" "unprognostic (5.06e-3)" "unprognostic (1.39e-3)" "unprognostic (1.56e-1)" "unprognostic (7.59e-2)" "unprognostic (1.41e-1)" 0.1 3.8 28.8 0.0 23.3 0.0 2.4 20.5 43.5 0.5 0.0 0.2 0.2 0.7 4.9 0.6 0.0 1.4 1.8 35.7 17.8 1.7 0.6 1.9 0.0 9.6 20.6 0.1 0.0 0.0 1.6 0.0 16.8 1.5 0.1 5.3 0.7 5.2 0.3 0.1 0.6 0.1 16.0 0.3 0.2 0.5 27.7 0.8 0.3 0.1 0.0 0.3 0.2 18.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 17.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 7.4 3.2 0.0 0.0 0.0 6.0 0.6 0.0 0.0 1.1 1.8 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 23.3 20.5 43.5 35.7 17.8 9.6 20.6 16.8 16.0 27.7 18.8 0.1 0.0 0.0 178.9 0.0 0.0 0.5 0.5 0.0 8.7 8.1 4.2 0.9 0.0 0.1 0.0 25.0 0.1 0.0 0.3 0.0 0.0 2.1 0.5 15.9 0.5 2.4 0.0 285.7 0.0 0.0 0.4 0.0 0.4 0.0 0.2 2.9 0.0 0.3 1.7 163.4 0.0 0.0 0.3 0.0 1.0 0.0 0.3 0.0 8.4 0.0 1.6 0.0 204.6 4.9 0.1 0.0 0.4 0.0 0.4 0.0 23.9 0.0 2.6 0.0 0.0 0.4 1.0 1.7 0.0 0.0 0.0 0.2 0.1 0.0 0.3 BRINP2 "DBCCR1L2, FAM5B" ENSG00000198797 "BMP/retinoic acid inducible neural specific 2" Q9C0B6 1 177170958-177282422 "Predicted secreted proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.6;brain: 19.9" "Group enriched" "Detected in some" 4 "Astrocytes: 121.1;Excitatory neurons: 116.8;Inhibitory neurons: 148.3;Oligodendrocyte precursor cells: 96.5" "Cancer enriched" "Detected in some" 5 "glioma: 11.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.7;PC-3: 1.3;REH: 2.1;SCLC-21H: 5.6;SH-SY5Y: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050681 Uncertain "Secreted in other tissues" NA NA "Cluster 65: Brain - Ion transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA050681: " "unprognostic (7.78e-2)" "unprognostic (4.49e-1)" "unprognostic (2.53e-1)" "unprognostic (1.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.43e-2)" "unprognostic (1.77e-1)" "unprognostic (5.77e-2)" "unprognostic (1.23e-2)" "unprognostic (1.95e-2)" "unprognostic (2.20e-4)" "unprognostic (8.95e-2)" "unprognostic (1.78e-2)" "unprognostic (2.60e-3)" "unprognostic (1.17e-1)" "unprognostic (2.60e-2)" "unprognostic (4.82e-3)" 0.6 9.6 17.2 0.0 16.5 0.0 0.9 1.3 19.9 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.2 17.9 10.7 0.0 0.1 0.0 0.0 4.5 9.6 0.0 0.0 0.0 4.2 0.5 4.9 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 4.9 0.4 0.0 2.1 16.2 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 2.1 0.0 0.0 0.0 0.0 5.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 16.5 1.3 19.9 17.9 10.7 4.5 9.6 4.9 4.9 16.2 13.4 0.0 0.0 0.0 121.1 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 3.4 0.2 0.3 0.0 0.0 0.0 116.8 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.0 0.0 0.1 15.2 148.3 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 25.3 0.0 0.5 0.0 96.5 15.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 1.3 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 BRINP3 "DBCCR1L, DBCCR1L1, FAM5C" ENSG00000162670 "BMP/retinoic acid inducible neural specific 3" Q76B58 1 190097658-190478404 "Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.1;intestine: 17.9" "Cell type enhanced" "Detected in some" "Astrocytes: 266.7;Excitatory neurons: 333.7;Inhibitory neurons: 129.7;Oligodendrocyte precursor cells: 1079.2" "Group enriched" "Detected in some" 14 "breast cancer: 3.4;glioma: 8.6;prostate cancer: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054693 Uncertain "Secreted in other tissues" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA054693: AB_2682575" "unprognostic (3.18e-2)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-1)" "unprognostic (8.25e-2)" "unprognostic (3.65e-1)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (9.84e-2)" "unprognostic (4.58e-3)" 0.3 1.7 19.8 0.6 16.8 0.0 1.4 18.7 19.2 0.2 0.0 6.6 4.6 0.2 3.0 1.7 0.4 1.6 5.3 27.1 25.8 2.3 0.0 1.2 0.0 12.5 15.7 0.0 0.0 0.0 0.2 0.0 12.4 6.8 6.7 0.7 1.6 5.1 0.1 0.1 17.9 0.6 13.1 0.0 0.2 3.4 26.0 0.1 2.1 0.0 0.1 0.5 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 16.8 18.7 19.2 27.1 25.8 12.5 15.7 12.4 13.1 26.0 10.4 0.0 0.0 0.0 266.7 0.0 0.0 0.1 0.0 0.0 0.7 0.3 0.4 2.3 0.0 0.0 3.7 0.0 0.0 0.0 2.0 3.9 0.0 63.3 0.0 0.0 0.1 1.2 0.0 333.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 129.7 2.8 0.0 0.0 0.0 10.5 0.0 0.1 0.0 8.4 0.0 0.0 0.0 1079.2 4.3 0.0 10.8 0.0 0.0 1.0 8.1 0.3 0.0 0.1 0.0 0.0 5.8 2.0 0.7 0.1 0.0 0.0 0.0 0.0 5.2 0.1 BRIP1 "BACH1, FANCJ, OF" ENSG00000136492 "BRCA1 interacting protein C-terminal helicase 1" Q9BX63 17 61679139-61863528 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.2;lymphoid tissue: 5.9;testis: 7.0" "Group enriched" "Detected in many" 12 "Early spermatids: 186.2;Late spermatids: 194.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005474 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear membrane" "HPA005474: AB_2667333" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "prognostic favorable (3.45e-5)" "unprognostic (6.85e-4)" "unprognostic (3.09e-1)" "prognostic favorable (3.62e-4)" "unprognostic (2.60e-3)" "unprognostic (5.60e-2)" "unprognostic (5.66e-3)" "unprognostic (6.71e-2)" "unprognostic (1.50e-3)" "unprognostic (2.75e-2)" "unprognostic (3.41e-12)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (3.96e-2)" "unprognostic (3.62e-3)" 0.3 0.3 0.8 1.7 0.6 7.2 0.9 1.3 0.9 0.4 0.0 1.7 2.0 0.8 0.4 1.5 0.3 0.6 0.1 0.5 0.2 0.3 1.6 0.4 2.8 0.3 0.0 1.1 0.3 0.1 0.0 0.8 0.4 0.4 1.9 0.5 0.4 0.2 0.1 2.0 1.9 0.9 0.0 0.7 0.9 7.0 0.2 5.9 0.3 0.1 3.3 0.7 0.6 0.8 26.6 9.4 25.0 14.1 0.9 2.1 5.5 23.6 13.3 24.6 31.8 9.5 8.0 14.9 5.2 4.9 7.7 9.2 12.8 4.5 33.3 3.8 15.8 15.5 14.4 10.5 0.2 20.3 8.8 0.6 0.4 20.2 5.1 3.4 5.0 14.8 11.6 10.5 14.4 88.9 32.5 6.7 5.3 5.9 7.3 19.7 50.1 7.1 3.0 12.8 10.0 24.2 9.4 3.0 3.3 9.1 8.3 7.3 4.5 36.9 26.5 13.5 26.6 6.3 13.3 16.6 7.3 9.3 8.8 1.0 0.1 0.4 0.1 0.0 0.1 0.5 0.3 0.1 0.1 0.6 0.4 0.2 0.3 0.1 0.1 0.1 1.0 0.1 0.8 0.6 1.3 0.9 0.5 0.2 0.3 0.0 0.4 0.0 0.2 0.8 0.2 0.0 0.5 1.0 1.6 2.3 1.3 0.8 0.6 0.3 1.1 1.8 0.6 0.0 4.0 0.0 0.0 2.0 2.0 1.8 0.0 0.3 186.2 0.7 1.7 0.8 0.0 7.4 4.6 0.2 3.0 2.0 2.0 1.6 0.0 15.5 0.4 3.4 1.7 0.0 3.3 1.8 0.0 0.8 1.1 194.1 1.2 1.0 3.6 2.8 0.6 0.2 1.0 1.5 1.0 0.8 0.1 1.2 4.8 0.4 1.4 0.2 0.8 0.2 0.0 2.5 1.8 12.1 6.0 2.9 0.4 0.3 2.3 2.1 4.7 0.7 BSCL2 "GNG3LG, seipin, SPG17" ENSG00000168000 "BSCL2 lipid droplet biogenesis associated, seipin" Q96G97 11 62690275-62709845 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid degradation, Lipid metabolism" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 292.1;pituitary gland: 237.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 35.9;Late spermatids: 53.1;Plasma cells: 86.3;Spermatocytes: 32.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 242.1;RPMI-8226: 176.1;SCLC-21H: 181.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042394 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA042394: AB_10794047" "unprognostic (7.78e-2)" "unprognostic (8.74e-2)" "unprognostic (1.24e-1)" "unprognostic (8.17e-2)" "unprognostic (3.08e-2)" "unprognostic (2.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (9.30e-2)" "unprognostic (4.44e-2)" "unprognostic (5.13e-3)" "unprognostic (2.41e-1)" "prognostic favorable (7.55e-5)" "unprognostic (3.56e-1)" "unprognostic (1.69e-1)" "unprognostic (1.70e-1)" "unprognostic (1.96e-1)" 24.9 88.1 126.6 7.4 133.2 12.0 26.2 75.0 155.6 38.2 85.4 24.3 10.8 28.4 156.7 24.1 63.7 21.5 18.7 134.9 292.1 50.8 39.3 26.7 15.3 138.1 139.0 32.7 79.4 61.7 237.0 10.0 203.4 35.4 13.3 52.6 66.1 30.3 30.9 25.1 17.2 13.7 83.1 16.2 37.1 190.3 169.3 14.4 37.9 15.5 8.9 17.5 26.1 89.9 18.0 61.7 49.6 83.8 130.8 41.5 7.2 7.2 34.4 13.6 14.5 9.6 26.3 11.9 16.5 25.2 11.8 62.1 5.2 21.8 7.0 30.7 5.0 10.9 33.4 7.8 27.7 9.7 13.5 27.8 16.6 26.9 10.9 19.7 10.8 33.0 7.8 242.1 19.8 44.0 11.4 21.8 132.4 13.9 13.0 21.3 4.2 176.1 65.0 2.4 181.2 29.4 28.2 13.9 25.3 5.7 41.3 15.3 6.5 16.5 3.7 24.5 4.2 32.2 72.5 16.6 82.4 3.2 14.5 26.6 59.2 34.6 24.7 46.2 27.4 27.5 25.5 26.1 42.4 29.7 25.7 27.0 14.2 41.0 40.3 54.3 33.1 43.3 126.6 133.2 75.0 155.6 134.9 292.1 138.1 139.0 203.4 83.1 169.3 89.9 0.8 16.0 5.6 0.0 7.1 1.7 1.0 1.4 35.9 2.5 3.6 2.2 0.2 1.5 1.6 3.7 0.0 2.4 0.9 1.7 3.9 2.0 25.5 4.8 1.5 2.9 0.0 8.8 0.0 1.1 1.9 9.2 20.4 1.5 2.5 0.7 1.4 2.1 1.9 3.3 0.0 1.6 6.1 2.5 3.1 53.1 2.5 6.2 12.4 0.0 0.7 0.8 1.0 0.0 0.0 0.5 1.6 3.0 86.3 0.9 2.5 6.0 23.9 1.2 6.6 1.2 4.1 32.6 18.1 24.7 4.0 1.5 6.5 0.7 1.2 0.5 BSG "CD147, EMMPRIN, EMPRIN, OK" ENSG00000172270 "Basigin (Ok blood group)" P35613 19 571277-583494 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1535.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1408.0;Syncytiotrophoblasts: 1654.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002427, HPA036048, HPA074870" Enhanced Approved Vesicles NA NA 340000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB002427: AB_563501, HPA036048: AB_2674917, HPA074870: AB_2686719" "unprognostic (1.88e-1)" "unprognostic (4.85e-2)" "unprognostic (9.53e-3)" "prognostic favorable (2.59e-4)" "unprognostic (3.34e-1)" "unprognostic (1.38e-2)" "prognostic unfavorable (5.48e-6)" "unprognostic (1.54e-3)" "unprognostic (1.55e-1)" "unprognostic (9.46e-2)" "unprognostic (4.48e-3)" "unprognostic (2.61e-2)" "prognostic favorable (1.95e-6)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (7.30e-2)" "unprognostic (3.22e-1)" 378.6 518.8 652.6 154.5 615.4 431.3 313.8 575.6 847.5 320.6 975.8 543.5 231.3 413.3 259.5 245.1 323.1 176.2 1535.0 629.0 606.0 469.7 186.0 253.6 101.9 578.5 611.2 300.7 301.6 255.3 331.2 320.2 599.8 228.8 155.9 189.6 274.8 194.4 472.3 226.6 239.7 164.1 551.0 200.0 455.8 486.0 724.3 92.8 302.1 292.2 74.2 366.9 233.0 581.2 622.6 739.3 339.5 852.3 975.0 426.0 800.4 499.2 507.6 506.1 437.9 607.1 569.4 208.4 564.3 383.5 148.7 967.8 341.0 575.0 129.6 468.1 840.3 150.0 545.5 812.3 683.6 361.6 679.0 455.5 578.5 302.4 304.5 613.1 383.3 198.3 722.9 992.5 298.6 1015.8 261.6 706.6 901.9 353.7 408.3 522.8 301.2 745.2 655.9 412.1 561.0 539.1 984.4 408.1 769.7 257.9 432.3 1118.9 478.7 557.5 353.4 940.1 751.5 639.7 701.8 201.1 1066.9 510.2 712.8 189.0 324.7 348.9 226.4 245.9 200.5 115.0 150.7 218.4 209.6 93.2 114.0 144.7 474.8 173.5 284.2 235.2 192.0 434.0 652.6 615.4 575.6 847.5 629.0 606.0 578.5 611.2 599.8 551.0 724.3 581.2 313.5 22.4 31.5 75.1 101.5 208.6 176.8 668.0 91.0 157.7 202.8 187.6 80.6 128.7 253.4 286.9 204.3 1408.0 156.5 1140.1 146.8 580.9 261.6 156.6 296.6 246.7 255.1 1091.4 35.4 371.4 1095.5 279.8 192.1 190.1 116.2 181.1 132.1 96.9 416.7 139.7 31.4 337.2 510.6 137.8 179.6 600.2 300.4 139.8 506.9 122.7 264.5 495.5 221.4 20.6 30.7 458.0 929.1 336.7 192.4 172.8 450.7 306.7 178.8 269.2 203.8 74.3 235.6 347.9 604.4 127.7 156.7 1654.9 130.9 223.5 478.2 181.4 BSPH1 "BSP1, ELSPBP2" ENSG00000188334 "Binder of sperm protein homolog 1" Q075Z2 19 47968046-47992170 "Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "epididymis: 383.0" "Cell type enhanced" "Detected in single" "Bipolar cells: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA048335 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA048335: AB_2732546" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 383.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 139.8;intestine: 48.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.8;Macrophages: 33.3;monocytes: 80.1;Proximal enterocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 257.7;neutrophil: 292.7" "Group enriched" "Detected in many" 95 "dendritic cells: 78.9;granulocytes: 292.7;monocytes: 257.7" "Cell line enhanced" "Detected in many" "THP-1: 76.0;TIME: 40.4;U-937: 52.5;WM-115: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" NA NA 190000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" 21.2 2.7 1.9 13.7 2.1 139.8 9.4 2.1 4.7 11.0 1.6 8.3 48.6 6.3 2.9 4.6 7.9 18.2 19.1 2.1 2.0 17.0 8.5 12.7 7.1 1.9 1.4 9.3 3.1 1.7 1.3 13.7 2.2 3.7 9.7 1.0 3.9 4.6 2.7 5.0 29.3 9.7 0.8 18.6 3.2 2.7 3.0 3.9 4.9 6.8 3.5 16.8 7.4 3.3 0.6 10.5 1.2 1.0 28.8 7.0 1.6 21.0 2.1 20.4 22.2 0.3 12.1 0.8 1.9 12.2 0.6 0.3 3.3 0.5 17.2 0.8 0.7 5.6 0.8 0.6 6.7 7.2 15.1 5.7 1.5 12.9 1.0 0.9 3.0 5.0 0.7 0.5 12.5 0.3 2.3 4.3 2.7 0.9 2.2 0.8 1.8 0.5 0.5 0.6 1.4 4.3 0.4 0.7 14.2 1.2 0.5 76.0 40.4 0.6 1.0 7.9 1.1 0.6 0.2 0.7 2.7 52.5 44.8 41.8 257.7 20.8 1.1 97.4 1.7 2.2 0.9 0.8 78.9 0.9 1.1 0.7 292.7 0.4 73.9 26.6 1.0 109.8 1.9 2.1 2.1 4.7 2.1 2.0 1.9 1.4 2.2 0.8 3.0 3.3 5.4 3.2 3.7 1.3 0.3 4.6 0.8 0.1 1.8 0.6 1.2 2.0 1.5 2.8 1.0 1.8 0.0 16.0 5.5 3.7 1.9 4.4 4.4 8.0 9.9 3.8 1.2 2.5 0.7 2.5 24.0 22.5 0.0 16.2 15.9 20.6 6.4 2.1 40.8 0.0 0.7 8.1 0.0 26.3 11.5 1.2 3.1 33.3 14.2 3.7 80.1 0.6 3.1 0.5 3.6 1.1 11.9 2.2 0.4 0.6 79.0 9.6 3.0 0.2 6.6 3.9 15.5 2.5 1.4 1.7 3.0 7.1 1.8 1.4 23.2 3.3 BTBD17 "BTBD17A, LGALS3BPL, TANGO10A" ENSG00000204347 "BTB domain containing 17" A6NE02 17 74356416-74361868 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "brain: 7.1" "Cell type enriched" "Detected in some" 6 "Horizontal cells: 28.6" "Cancer enriched" "Detected in some" 5 "glioma: 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "AF22: 2.9;NTERA-2: 3.8;SCLC-21H: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA025022 Approved "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "HPA025022: AB_2067352" "unprognostic (2.63e-1)" "unprognostic (2.77e-1)" "unprognostic (4.82e-5)" "unprognostic (3.89e-2)" "unprognostic (2.55e-1)" "unprognostic (9.89e-3)" 0.0 0.5 2.8 0.0 2.7 0.0 0.0 1.7 3.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 0.0 0.0 0.0 2.5 3.5 0.0 0.2 0.0 0.2 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.4 0.3 7.1 0.0 0.2 0.0 0.0 0.0 0.0 2.3 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.7 1.7 3.3 2.3 5.7 2.5 3.5 2.8 2.5 7.1 2.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 4.2 0.0 0.0 0.0 4.2 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.1 4.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.6 0.1 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 3.5 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.6 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 BTD ENSG00000169814 Biotinidase P43251 3 15601341-15722311 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 95.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052275 Uncertain "Secreted to blood" NA NA 2800000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA052275: AB_2681782" "unprognostic (6.04e-2)" "unprognostic (2.42e-1)" "unprognostic (9.37e-3)" "unprognostic (5.84e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-2)" "unprognostic (6.37e-3)" "unprognostic (4.26e-2)" "unprognostic (3.29e-2)" "unprognostic (1.23e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "prognostic favorable (2.60e-9)" "unprognostic (2.44e-2)" "unprognostic (4.90e-2)" "unprognostic (1.67e-3)" "unprognostic (3.73e-2)" 25.3 16.7 10.7 8.0 12.7 13.1 16.4 20.2 12.6 13.7 11.0 15.9 46.1 13.2 62.4 9.9 18.3 19.9 10.2 11.5 10.3 37.6 95.9 15.9 9.6 12.0 10.0 25.3 44.1 27.7 5.9 17.0 12.6 19.5 17.0 35.2 16.0 21.1 7.8 9.5 30.7 14.1 10.3 11.3 24.4 18.2 9.9 10.6 26.8 11.4 10.4 14.3 7.5 19.1 9.2 22.0 7.8 7.3 51.7 15.3 39.6 15.4 18.4 16.2 28.3 10.1 21.5 4.1 16.3 31.6 7.1 9.7 5.3 16.7 18.7 7.6 11.7 12.9 28.8 24.8 12.7 8.8 14.7 18.3 16.9 42.9 5.1 39.7 30.5 5.9 8.7 32.3 44.7 11.1 4.5 8.2 8.5 16.9 13.0 5.9 18.4 27.9 16.5 17.7 5.3 11.8 17.9 5.2 24.4 15.1 19.9 11.3 24.3 20.5 13.6 19.1 10.1 8.9 11.4 4.1 21.4 7.7 14.4 74.1 20.7 44.9 22.9 19.6 21.0 14.7 23.3 19.2 21.4 13.1 19.7 15.4 19.8 15.0 15.8 24.9 28.8 16.5 10.7 12.7 20.2 12.6 11.5 10.3 12.0 10.0 12.6 10.3 9.9 19.1 14.9 6.4 11.0 11.8 11.7 5.9 12.4 25.0 6.2 13.5 9.1 7.9 6.0 45.8 16.7 18.4 18.8 25.3 19.7 9.9 5.9 21.1 31.0 9.5 6.0 9.1 7.2 4.0 6.6 28.5 22.4 14.5 9.7 5.7 5.1 8.9 20.3 63.3 14.9 5.0 12.2 8.5 16.2 8.2 5.9 17.9 32.3 9.2 10.6 5.6 8.7 19.2 6.2 27.2 23.9 12.0 17.9 18.0 16.6 6.3 52.1 32.0 19.8 54.1 13.1 8.5 8.6 45.3 7.5 7.7 5.5 23.1 13.6 17.4 8.9 9.5 BTN2A2 "BT2.2, BTF2, BTN2.2" ENSG00000124508 "Butyrophilin subfamily 2 member A2" Q8WVV5 6 26383096-26394874 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 30.3;Plasma cells: 30.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 72.8;U-266/70: 58.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA051504 Uncertain Approved Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "HPA051504: AB_2681510" "prognostic favorable (1.01e-4)" "unprognostic (4.93e-3)" "unprognostic (1.37e-2)" "unprognostic (6.78e-2)" "unprognostic (9.26e-2)" "unprognostic (2.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.04e-3)" "unprognostic (1.01e-1)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (1.93e-1)" "unprognostic (1.73e-2)" "unprognostic (3.45e-1)" "unprognostic (6.54e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-3)" 7.2 13.5 5.4 21.9 6.9 4.3 8.7 14.4 6.0 7.9 21.2 8.0 7.2 10.2 7.5 5.1 8.4 8.5 4.9 6.8 5.9 7.5 6.1 16.2 32.1 7.5 6.9 10.4 5.2 17.5 5.7 4.0 7.8 8.3 10.5 2.9 12.1 6.8 2.8 11.0 11.3 10.9 6.5 21.8 10.4 6.1 6.2 15.2 7.5 4.2 36.6 8.2 6.9 6.9 10.6 6.6 13.2 14.2 4.4 6.8 0.9 11.4 29.7 17.4 30.0 4.2 4.1 9.6 12.1 20.5 14.1 9.5 10.7 8.7 23.1 29.9 17.9 15.0 13.2 8.4 9.1 3.4 5.1 14.5 2.7 33.5 11.3 20.7 16.3 18.5 12.3 72.8 7.9 4.6 12.1 4.4 5.0 0.4 6.6 28.1 18.7 29.8 12.7 5.9 12.6 17.6 7.4 2.8 31.1 7.5 13.5 6.6 19.5 6.4 7.3 5.6 17.7 58.9 38.8 16.9 6.4 13.4 16.3 2.1 13.7 2.4 6.1 14.6 5.8 24.1 5.0 5.7 23.9 29.4 4.1 5.1 12.4 8.7 6.3 9.7 10.3 7.9 5.4 6.9 14.4 6.0 6.8 5.9 7.5 6.9 7.8 6.5 6.2 6.9 8.1 9.6 12.6 0.0 30.3 3.8 7.3 6.5 6.2 0.6 5.2 5.1 2.5 2.8 8.5 3.7 0.0 2.3 15.0 0.6 0.0 8.6 0.4 8.8 4.5 13.1 1.8 3.6 0.0 5.6 0.8 5.0 3.6 7.5 19.6 9.6 6.1 3.8 8.4 0.0 0.0 7.8 12.2 16.0 24.2 0.6 6.5 17.1 7.2 0.0 15.4 14.3 7.2 0.0 0.0 8.3 0.8 4.9 30.7 6.4 2.6 2.3 10.2 0.7 0.0 5.0 4.4 0.3 1.5 4.5 4.5 1.0 10.0 10.6 2.1 4.2 BTN3A1 "BT3.1, BTF5, BTN3.1, CD277" ENSG00000026950 "Butyrophilin subfamily 3 member A1" O00481 6 26402237-26415208 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 59.1;NK-cells: 73.2;Plasma cells: 47.6;T-cells: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA012565 Approved Uncertain Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA012565: AB_1845494" "unprognostic (2.82e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-3)" "unprognostic (4.72e-3)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (3.10e-2)" "unprognostic (9.31e-2)" "unprognostic (9.81e-2)" "unprognostic (8.60e-3)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "prognostic unfavorable (4.15e-5)" "unprognostic (2.45e-1)" "unprognostic (5.02e-2)" "unprognostic (3.26e-2)" "prognostic favorable (4.81e-4)" 19.2 20.7 10.2 44.8 11.1 29.6 20.1 9.8 10.5 21.2 10.3 24.8 28.5 28.0 16.0 11.9 22.5 30.5 12.1 9.1 12.1 12.8 18.9 41.4 63.4 16.4 10.9 35.1 13.1 13.1 13.7 19.2 12.5 16.5 28.8 3.6 23.9 13.5 12.8 24.9 35.1 21.3 12.2 84.0 31.3 5.0 11.4 33.1 11.5 14.5 52.6 20.0 17.4 12.0 7.4 6.2 9.3 9.5 25.9 27.5 1.2 6.2 24.1 13.5 39.4 0.3 16.7 19.7 20.4 11.2 20.9 5.1 3.0 9.7 8.2 19.5 6.4 10.4 8.5 4.7 11.8 9.5 9.3 15.0 5.6 11.8 5.4 20.4 19.3 31.0 2.5 25.3 5.5 0.6 17.6 6.6 1.0 3.3 2.1 24.2 4.0 45.2 8.3 9.4 4.9 9.8 3.4 7.1 13.5 1.4 6.5 4.0 4.8 10.3 2.6 3.1 5.9 41.8 45.9 7.3 15.6 21.4 8.4 53.8 11.1 28.8 44.7 11.7 40.4 18.8 27.8 42.3 9.1 10.5 24.1 32.0 23.9 40.5 12.9 4.3 36.0 28.0 10.2 11.1 9.8 10.5 9.1 12.1 16.4 10.9 12.5 12.2 11.4 12.0 24.8 16.0 6.5 0.0 27.1 4.2 3.9 3.5 2.2 4.3 8.6 8.1 4.2 11.5 8.5 5.5 0.0 5.5 59.1 8.2 0.0 7.4 0.1 5.5 10.4 18.0 4.8 13.3 0.0 3.2 4.3 9.9 9.2 10.3 25.9 14.0 11.7 3.9 7.2 0.0 0.0 17.3 2.0 19.2 6.1 0.8 3.7 15.4 1.8 0.0 13.7 1.9 73.2 0.0 0.0 2.2 6.3 2.6 47.6 5.4 15.9 1.3 6.7 0.4 0.0 6.7 5.5 0.0 0.1 3.6 3.3 1.5 50.1 8.4 7.4 5.0 BTN3A2 BTN3.2 ENSG00000186470 "Butyrophilin subfamily 3 member A2" P78410 6 26365159-26378320 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 88.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.2;NK-cells: 239.9;T-cells: 108.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 87.5" CAB019392 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB019392: " "unprognostic (3.77e-2)" "unprognostic (1.17e-2)" "unprognostic (3.73e-2)" "unprognostic (2.86e-2)" "unprognostic (3.66e-2)" "unprognostic (1.60e-1)" "unprognostic (1.40e-1)" "unprognostic (3.89e-1)" "unprognostic (4.04e-2)" "unprognostic (1.30e-3)" "unprognostic (1.12e-1)" "unprognostic (8.45e-2)" "prognostic unfavorable (4.24e-4)" "unprognostic (5.13e-2)" "unprognostic (4.45e-2)" "unprognostic (4.42e-2)" "unprognostic (1.48e-3)" 19.4 27.3 8.6 41.9 8.5 9.5 18.4 7.6 8.7 18.1 7.9 29.0 29.3 21.7 21.0 13.5 22.0 25.0 13.8 7.3 9.3 15.8 23.6 41.0 45.5 13.1 8.9 29.6 10.4 10.4 12.7 18.4 9.9 14.9 31.7 2.4 19.4 14.9 8.4 21.7 32.9 20.8 10.5 88.3 32.6 7.1 8.7 38.3 14.4 10.7 44.6 22.9 17.0 10.9 10.6 4.8 6.4 6.7 37.4 42.9 2.2 10.2 48.2 18.8 52.6 2.7 34.4 30.6 35.5 16.2 27.5 9.2 9.4 18.6 17.1 18.5 13.2 33.1 19.1 20.1 20.7 18.9 26.5 27.0 7.5 17.9 8.5 43.9 36.0 54.0 8.5 41.1 13.1 1.4 16.2 30.4 0.4 8.6 3.6 24.3 11.5 87.5 17.1 6.5 4.2 12.8 8.2 7.5 25.7 1.9 7.5 14.0 22.4 17.7 4.0 7.6 11.3 86.1 79.7 17.7 32.2 33.2 17.5 67.7 26.7 57.6 128.3 35.9 96.1 64.5 81.3 113.8 19.2 53.4 81.8 100.1 40.0 98.8 47.5 13.5 111.2 71.3 8.6 8.5 7.6 8.7 7.3 9.3 13.1 8.9 9.9 10.5 8.7 10.9 62.5 32.1 22.2 2.3 61.3 10.3 12.2 8.6 13.1 0.7 16.0 9.9 7.5 17.2 7.4 12.9 0.0 14.3 117.2 21.8 1.9 25.6 0.2 23.6 21.3 46.0 10.1 25.2 1.0 13.7 17.3 20.2 15.8 14.7 47.4 23.4 40.0 9.8 17.8 0.0 2.5 37.9 10.2 54.0 10.0 1.9 11.1 37.1 3.6 20.6 52.7 7.0 239.9 7.1 1.7 10.6 16.9 10.5 76.6 13.2 50.5 3.8 11.8 1.4 13.1 15.7 10.2 1.5 0.2 8.3 13.4 3.3 108.0 51.0 25.5 16.8 BTN3A3 "BTF3, BTN3.3" ENSG00000111801 "Butyrophilin subfamily 3 member A3" O00478 6 26440472-26453415 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 26.9;NK-cells: 33.0;Plasma cells: 30.5;T-cells: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 62.8;BJ hTERT+ SV40 Large T+ RasG12V: 43.8" "HPA007904, HPA011871" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "HPA007904: AB_1078307, HPA011871: AB_1845496" "unprognostic (1.18e-2)" "unprognostic (6.54e-3)" "unprognostic (1.54e-1)" "unprognostic (1.19e-2)" "unprognostic (2.30e-2)" "unprognostic (8.60e-2)" "unprognostic (5.13e-3)" "unprognostic (8.08e-2)" "unprognostic (7.88e-2)" "prognostic favorable (1.80e-4)" "unprognostic (4.45e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.42e-5)" "unprognostic (3.49e-2)" "unprognostic (2.14e-2)" "unprognostic (5.26e-2)" "unprognostic (4.54e-3)" 14.9 19.6 7.4 20.0 7.0 5.5 12.0 6.5 7.9 16.6 8.0 15.0 17.5 16.7 18.7 8.3 20.3 20.3 9.0 7.2 9.0 8.9 20.6 33.7 29.2 10.0 7.2 19.5 4.8 5.0 12.2 10.2 7.6 9.4 14.6 1.8 12.3 11.2 5.8 11.6 16.7 17.1 9.0 47.2 16.3 3.3 7.5 21.5 9.2 14.4 22.8 16.7 9.5 8.2 4.1 1.8 1.8 1.6 33.2 62.8 0.5 5.4 29.7 12.0 43.8 0.0 12.3 25.0 24.5 9.0 11.1 2.9 2.6 9.7 5.8 21.4 4.2 11.5 11.8 1.3 24.2 6.4 2.1 33.4 3.8 10.5 3.9 19.3 24.1 9.4 0.5 3.7 6.7 0.0 16.7 5.3 0.1 0.0 2.9 16.7 3.3 24.9 9.4 3.3 2.2 3.9 3.3 3.1 6.2 0.4 0.8 3.5 15.0 5.8 1.3 6.5 3.8 4.1 1.0 2.5 15.4 12.0 6.2 49.0 15.7 13.4 54.7 23.2 43.7 19.3 37.6 55.5 12.4 14.0 36.3 49.0 11.6 45.9 24.6 6.4 46.2 33.3 7.4 7.0 6.5 7.9 7.2 9.0 10.0 7.2 7.6 9.0 7.5 8.2 20.3 9.6 7.7 0.3 15.9 1.8 1.9 2.8 8.0 0.2 3.6 2.8 4.9 0.0 5.2 0.0 0.0 2.5 26.9 6.4 1.9 5.3 4.6 4.2 9.4 22.1 1.2 9.9 1.4 2.3 1.6 11.1 7.1 4.3 3.8 8.7 15.7 4.0 4.3 0.0 2.1 8.9 0.0 20.8 4.0 18.0 4.1 12.4 3.6 2.8 12.6 2.3 33.0 1.5 0.4 2.4 3.9 2.2 30.5 2.0 12.8 1.1 3.3 0.0 6.6 4.9 4.0 0.4 0.3 3.1 2.0 0.5 27.1 12.3 6.2 1.9 BTNL2 "BTL-II, BTN7, HSBLMHC1" ENSG00000204290 "Butyrophilin like 2" Q9UIR0 6 32393963-32407128 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.04e-2)" "unprognostic (1.54e-1)" "unprognostic (1.50e-2)" "unprognostic (8.13e-4)" "unprognostic (3.74e-2)" "unprognostic (1.33e-1)" "unprognostic (1.21e-1)" "unprognostic (3.04e-1)" "unprognostic (9.36e-2)" "unprognostic (2.41e-3)" "unprognostic (2.07e-1)" "unprognostic (3.67e-1)" "unprognostic (8.03e-2)" 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BZW2 "HSPC028, MST017, MSTP017" ENSG00000136261 "Basic leucine zipper and W2 domains 2" Q9Y6E2 7 16646131-16706523 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 265.5;skeletal muscle: 367.7;tongue: 258.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 278.2;Extravillous trophoblasts: 875.6;Syncytiotrophoblasts: 762.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022813, HPA026709" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Cytosol" "HPA022813: AB_1845511, HPA026709: AB_10600752" "unprognostic (2.27e-3)" "unprognostic (1.77e-3)" "unprognostic (5.91e-2)" "unprognostic (4.79e-3)" "unprognostic (2.80e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (7.86e-8)" "unprognostic (9.13e-3)" "unprognostic (8.49e-3)" "unprognostic (2.81e-2)" "unprognostic (1.83e-3)" "unprognostic (3.37e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.00e-1)" "unprognostic (1.66e-1)" "unprognostic (6.77e-2)" "unprognostic (1.25e-1)" 26.1 18.1 8.5 26.8 10.1 45.7 49.7 6.9 14.3 19.1 9.7 51.2 28.9 18.4 9.9 42.6 20.2 17.2 265.5 10.2 6.3 37.8 18.4 20.0 30.0 5.2 6.3 16.0 30.0 6.7 10.4 80.4 6.5 19.3 56.8 88.0 23.8 34.3 367.7 55.5 30.0 39.0 5.6 16.5 50.2 11.6 6.9 33.0 36.5 258.9 38.4 59.5 26.2 8.8 91.7 81.3 138.2 201.7 67.5 118.3 125.7 126.0 156.3 117.6 124.9 201.8 129.7 208.0 143.7 96.9 87.6 181.6 164.8 141.5 152.0 27.8 99.8 129.6 84.4 117.0 70.5 180.3 79.1 90.6 74.6 104.0 187.7 92.4 171.6 149.7 251.9 43.5 96.9 105.0 90.0 210.4 143.9 259.5 174.1 111.0 91.2 216.6 113.4 152.6 179.9 106.8 50.8 419.9 67.7 156.7 187.8 149.5 97.6 93.1 119.1 141.5 136.3 89.5 92.8 288.1 45.5 220.6 340.3 2.6 46.0 5.0 27.3 55.2 44.6 44.6 39.8 36.9 98.8 42.9 56.8 47.1 2.1 56.8 41.6 38.5 31.8 44.0 8.5 10.1 6.9 14.3 10.2 6.3 5.2 6.3 6.5 5.6 6.9 8.8 32.8 22.4 60.5 3.9 30.0 57.6 69.9 60.5 82.6 55.9 52.3 57.0 278.2 17.2 53.9 47.8 64.6 214.3 26.8 42.4 58.7 47.5 9.8 31.9 43.2 42.9 30.5 63.5 48.6 65.6 875.6 43.5 110.1 40.6 21.0 33.3 8.9 13.7 65.0 6.7 32.0 49.5 61.1 33.4 46.0 6.4 12.2 30.7 24.9 12.2 47.5 19.7 19.6 19.1 17.9 47.0 42.9 9.8 31.9 52.0 19.2 20.8 32.6 106.4 6.6 30.2 54.2 11.3 4.1 99.6 51.6 762.9 29.3 52.6 90.6 79.0 C10orf105 FLJ00245 ENSG00000214688 "Chromosome 10 open reading frame 105" Q8TEF2 10 71711701-71737824 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 34.6" "Group enriched" "Detected in some" 4 "Early spermatids: 8.7;Langerhans cells: 2.4;Late spermatids: 5.1;Melanocytes: 3.6" "Cancer enriched" "Detected in single" 9 "glioma: 0.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.8;non-classical monocyte: 2.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 5 "BJ hTERT+: 3.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (2.60e-3)" "unprognostic (6.76e-3)" "unprognostic (5.45e-1)" "unprognostic (4.14e-1)" "unprognostic (1.17e-1)" "unprognostic (1.37e-6)" "unprognostic (5.25e-2)" "unprognostic (2.10e-3)" "unprognostic (1.47e-1)" "unprognostic (8.08e-2)" "unprognostic (3.87e-2)" "unprognostic (1.35e-1)" "unprognostic (7.37e-2)" "unprognostic (4.64e-1)" "unprognostic (1.53e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" 0.6 0.0 14.4 0.7 15.0 0.5 0.1 13.8 7.7 0.2 4.2 0.1 0.2 0.1 0.0 0.1 0.4 0.2 0.2 9.2 19.4 0.0 0.1 0.5 1.1 27.3 34.6 0.5 0.0 0.0 0.1 0.1 19.2 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.2 0.0 17.3 2.8 0.1 1.4 22.5 0.5 0.0 0.1 0.4 0.1 0.2 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 2.1 0.0 0.0 0.1 14.4 15.0 13.8 7.7 9.2 19.4 27.3 34.6 19.2 17.3 22.5 13.6 0.4 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.4 5.1 0.0 0.7 3.6 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 C10orf95 FLJ14280 ENSG00000120055 "Chromosome 10 open reading frame 95" 10 102449837-102451543 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 9.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 30.1;Rod photoreceptor cells: 18.4;Syncytiotrophoblasts: 38.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 11.8;JURKAT: 11.7" "Low region specificity" "Detected in single" "Secreted - unknown location" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (2.31e-1)" "unprognostic (7.76e-3)" "unprognostic (3.19e-1)" "unprognostic (5.62e-3)" "unprognostic (4.02e-1)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (5.98e-2)" "unprognostic (1.50e-2)" "unprognostic (1.01e-1)" "unprognostic (4.42e-2)" "unprognostic (2.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (2.14e-1)" "unprognostic (1.22e-2)" "unprognostic (4.80e-3)" 0.5 1.5 0.7 1.8 0.6 2.0 0.2 2.8 1.1 1.1 0.9 1.2 2.5 1.2 0.4 1.3 9.7 1.4 0.6 0.6 0.8 1.4 0.4 3.5 2.9 0.3 0.2 1.1 4.7 0.1 1.3 0.7 0.1 1.6 0.4 4.7 4.0 0.1 0.7 4.1 2.3 0.0 0.0 2.6 3.6 0.7 0.9 0.0 5.3 0.0 0.5 0.6 0.5 0.1 5.7 1.1 0.1 2.3 0.0 0.0 4.9 0.2 0.0 0.0 0.0 4.4 9.8 5.0 2.2 0.0 0.7 9.8 0.0 0.4 0.0 4.3 11.8 3.2 4.7 3.7 0.0 4.4 3.0 0.1 1.8 0.0 0.1 3.1 0.0 11.7 5.6 4.1 0.0 4.5 2.4 4.2 2.2 2.0 3.3 7.0 0.1 5.4 1.1 2.0 8.8 1.3 2.4 1.5 3.1 1.7 4.8 0.3 0.4 0.2 1.0 0.2 0.5 3.5 2.9 3.3 0.2 6.5 0.1 2.1 1.2 1.7 7.8 0.6 7.4 10.7 8.4 7.9 3.6 8.3 11.7 9.9 0.9 10.1 0.3 6.3 9.6 4.9 0.7 0.6 2.8 1.1 0.6 0.8 0.3 0.2 0.1 0.0 0.9 0.1 0.3 0.0 3.2 0.7 3.1 1.5 4.3 0.5 0.0 4.6 2.4 2.5 0.1 2.8 4.2 5.5 10.4 2.3 6.4 2.5 3.9 1.5 0.1 30.1 0.7 1.0 1.2 1.3 0.7 1.1 1.7 0.3 1.5 4.0 0.0 0.8 0.4 0.3 2.3 3.3 0.7 3.7 4.1 1.0 1.0 0.5 0.6 1.4 0.0 0.0 2.2 2.7 6.2 0.0 0.0 0.7 0.4 0.7 2.5 3.3 2.0 4.2 8.7 18.4 0.0 0.9 0.5 0.7 1.4 1.9 1.6 38.0 3.2 0.7 3.2 2.9 C10orf99 "AP-57, CSBF, FLJ21763, RLLV1833, UNQ1833" ENSG00000188373 "Chromosome 10 open reading frame 99" Q6UWK7 10 84173801-84185294 "Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 193.2;intestine: 274.9;vagina: 115.3" "Group enriched" "Detected in some" 11 "Distal enterocytes: 853.2;Intestinal goblet cells: 267.6;Paneth cells: 815.9;Proximal enterocytes: 364.8;Undifferentiated cells: 402.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 91.5;head and neck cancer: 102.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 52.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050920 Enhanced "Secreted in other tissues" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA050920: AB_2681274" "unprognostic (3.13e-2)" "unprognostic (1.43e-1)" "unprognostic (6.04e-2)" "unprognostic (1.78e-2)" "unprognostic (7.46e-3)" "unprognostic (2.05e-1)" "unprognostic (7.98e-2)" "unprognostic (2.04e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (3.70e-1)" "unprognostic (4.67e-2)" 0.4 0.0 0.0 16.8 0.0 0.0 0.5 0.0 0.0 46.7 0.0 268.5 0.0 0.6 0.0 193.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 274.9 0.1 21.7 2.6 0.0 38.5 21.5 13.1 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.0 17.4 33.5 115.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.4 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 6.8 1.2 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.1 853.2 0.0 0.0 0.4 3.3 0.8 0.1 28.9 0.0 0.0 0.0 0.0 0.0 0.0 4.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 267.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 815.9 0.0 0.0 1.0 364.8 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 46.0 2.3 0.0 1.4 0.0 402.8 46.4 C11orf24 DM4E3 ENSG00000171067 "Chromosome 11 open reading frame 24" Q96F05 11 68261338-68272001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 107.7;Proximal enterocytes: 162.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 222.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012411, HPA012748" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" Vesicles "HPA012411: , HPA012748: AB_1845526" "unprognostic (1.13e-2)" "unprognostic (2.03e-2)" "unprognostic (1.19e-1)" "unprognostic (8.22e-2)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.31e-2)" "unprognostic (7.91e-2)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.56e-1)" "unprognostic (2.68e-2)" "unprognostic (4.99e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.60e-9)" "unprognostic (2.18e-2)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (8.67e-3)" 25.0 17.6 8.9 20.7 12.2 4.7 21.0 12.1 12.7 23.3 8.2 29.2 53.8 39.2 7.3 15.5 22.2 17.6 31.5 9.7 10.5 17.0 87.4 24.1 15.5 14.4 11.6 19.3 27.3 7.3 14.5 16.1 12.5 22.9 17.4 3.0 34.0 17.6 13.7 15.4 59.4 32.6 11.0 20.8 23.6 14.6 12.8 6.4 17.0 15.2 16.7 22.3 19.4 15.2 44.8 45.5 26.4 51.6 62.1 62.5 29.7 105.4 67.5 51.8 53.1 96.2 26.9 20.1 31.7 131.3 47.2 49.4 39.1 47.4 33.2 22.1 23.1 21.4 44.8 65.3 50.1 18.3 68.7 52.1 34.6 78.8 32.0 31.0 21.2 10.6 37.9 32.2 44.6 55.7 4.5 26.4 44.2 72.1 53.8 8.2 44.8 104.1 23.9 21.1 17.3 31.8 33.3 27.1 222.8 21.8 25.6 15.3 23.3 80.8 50.2 103.3 47.3 39.4 41.4 18.8 65.1 14.1 79.9 16.7 12.1 12.6 14.0 19.0 9.4 26.7 7.9 8.9 19.5 35.7 7.3 7.7 1.8 9.9 14.1 26.7 8.4 12.6 8.9 12.2 12.1 12.7 9.7 10.5 14.4 11.6 12.5 11.0 12.8 15.2 6.8 9.6 3.6 3.3 25.5 14.0 12.2 11.7 9.6 4.8 8.2 8.9 10.4 11.5 6.9 9.2 2.1 11.9 12.4 36.2 1.9 21.9 3.5 5.3 17.8 6.6 4.8 9.1 4.1 31.5 30.7 21.1 18.3 6.8 45.0 5.0 9.3 107.7 15.8 0.0 4.2 50.0 6.1 12.9 23.5 7.1 14.0 12.3 28.4 5.6 14.9 6.8 18.6 6.6 8.5 26.9 16.6 16.1 67.0 13.0 162.5 10.6 9.4 2.9 13.1 11.2 20.2 20.7 27.1 9.6 11.2 10.5 6.5 9.6 15.5 10.6 C11orf45 "FLJ43646, MGC35558" ENSG00000174370 "Chromosome 11 open reading frame 45" Q8TAV5 11 128899565-128906035 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.7;Hofbauer cells: 8.7;Kupffer cells: 5.9;Late spermatids: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 11.2;U-937: 8.9" HPA039716 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA039716: AB_10672892" "unprognostic (8.32e-2)" "unprognostic (3.93e-2)" "unprognostic (5.99e-3)" "unprognostic (1.35e-3)" "unprognostic (1.01e-1)" "unprognostic (9.93e-2)" "unprognostic (4.50e-5)" "unprognostic (1.97e-2)" "unprognostic (4.78e-2)" "unprognostic (3.10e-1)" "unprognostic (2.80e-1)" "unprognostic (9.27e-2)" "unprognostic (2.55e-9)" "unprognostic (2.37e-1)" "unprognostic (2.60e-2)" "unprognostic (6.87e-2)" "unprognostic (7.22e-2)" 0.6 3.3 1.7 0.7 4.4 0.8 0.9 0.6 2.1 1.0 0.8 0.7 1.4 0.5 0.6 2.9 1.0 2.0 4.5 1.4 1.6 2.0 0.5 2.6 0.8 1.9 1.9 0.9 2.6 3.8 2.3 2.1 1.6 1.1 0.9 0.2 1.6 2.8 0.1 6.6 0.9 0.5 1.1 1.5 1.8 1.1 2.3 2.4 1.8 0.2 0.9 1.2 1.3 2.2 2.4 4.5 0.0 0.0 0.3 0.4 1.6 0.8 4.7 1.7 4.2 6.3 5.8 0.0 3.2 0.5 4.2 2.3 2.4 11.2 0.8 0.0 1.1 0.3 2.7 0.0 0.2 0.0 0.0 0.3 1.5 1.3 0.9 3.8 1.0 3.5 0.0 0.2 2.0 1.2 2.6 2.4 1.8 1.0 3.9 1.1 4.6 0.5 3.9 1.1 0.0 0.2 1.8 5.0 0.3 1.2 0.8 4.4 0.5 0.0 6.2 0.0 0.8 0.1 0.0 0.0 0.8 8.9 0.2 0.0 0.6 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.9 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.7 4.4 0.6 2.1 1.4 1.6 1.9 1.9 1.6 1.1 2.3 2.2 0.1 0.0 0.5 0.0 0.0 2.8 1.3 0.9 5.7 0.0 0.3 0.4 1.7 0.0 0.2 0.0 0.0 2.0 0.0 0.1 1.9 1.0 2.0 0.3 0.1 0.2 0.0 0.0 0.3 0.8 2.1 0.3 0.0 0.5 1.3 0.3 0.4 0.0 8.7 0.0 0.2 0.1 0.0 5.9 0.8 8.2 0.0 2.2 0.0 2.8 0.6 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 1.5 1.7 3.0 0.9 1.2 0.2 0.1 0.2 1.1 C11orf94 ENSG00000234776 "Chromosome 11 open reading frame 94" C9JXX5 11 45906513-45907272 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 148 "testis: 54.7" "Group enriched" "Detected in some" 82 "Early spermatids: 390.0;Late spermatids: 189.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (1.55e-1)" "unprognostic (2.71e-1)" "unprognostic (2.28e-1)" "unprognostic (2.36e-1)" "unprognostic (7.28e-2)" "unprognostic (5.99e-2)" "unprognostic (6.21e-3)" "unprognostic (1.97e-1)" "unprognostic (1.43e-1)" "unprognostic (7.11e-2)" "unprognostic (3.33e-2)" "unprognostic (4.24e-2)" "unprognostic (9.05e-4)" "unprognostic (1.90e-1)" "unprognostic (1.10e-1)" "unprognostic (3.28e-1)" "unprognostic (1.47e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 390.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 189.9 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 3.5 1.6 0.0 0.0 0.0 0.0 0.1 0.2 0.1 C12orf40 FLJ40126 ENSG00000180116 "Chromosome 12 open reading frame 40" Q86WS4 12 39626167-39908300 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 40 "testis: 8.7" "Cell type enhanced" "Detected in some" "Early spermatids: 11.5;Late spermatids: 5.2;Spermatocytes: 33.2;Spermatogonia: 7.6" "Cancer enriched" "Detected in single" 12 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "K-562: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA039032 Approved "Golgi apparatus,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" Cytosol "HPA039032: AB_2676316" "unprognostic (1.75e-1)" "unprognostic (2.76e-6)" "unprognostic (3.45e-1)" "unprognostic (1.96e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 7.6 0.0 0.0 0.0 0.3 0.1 0.0 0.0 C12orf65 "FLJ38663, SPG55" ENSG00000130921 "Chromosome 12 open reading frame 65" Q9H3J6 12 123233385-123258079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057595 Approved Approved Nucleoplasm,Mitochondria,Cytosol No Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" Mitochondria "HPA057595: " "unprognostic (9.07e-3)" "unprognostic (1.51e-2)" "unprognostic (5.30e-2)" "unprognostic (8.19e-3)" "unprognostic (1.23e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (4.29e-9)" "unprognostic (9.33e-3)" "unprognostic (2.39e-1)" "unprognostic (2.50e-2)" "unprognostic (6.33e-3)" "unprognostic (1.20e-2)" "unprognostic (2.01e-2)" "unprognostic (3.89e-2)" "unprognostic (3.19e-2)" "unprognostic (9.83e-3)" "prognostic favorable (7.82e-5)" 7.3 12.6 16.2 10.2 16.1 9.0 8.0 23.0 19.6 13.0 13.5 10.9 11.4 12.1 13.8 9.5 11.4 8.2 15.0 16.0 13.2 12.6 14.5 8.9 18.2 12.6 12.3 17.2 8.5 10.2 19.7 7.3 14.9 13.7 8.2 15.7 16.2 9.0 13.0 13.8 11.3 7.0 8.8 12.8 10.6 16.7 14.8 60.0 12.3 12.5 13.4 10.3 11.0 18.3 28.4 20.5 20.8 39.1 12.0 11.1 13.7 22.3 16.5 25.1 18.0 21.8 15.8 36.1 20.3 8.4 23.5 20.4 25.7 12.5 25.0 29.2 22.5 44.0 20.7 18.6 26.1 20.4 19.7 14.2 33.2 18.9 35.1 37.0 17.0 53.6 45.6 13.4 16.7 12.3 46.2 39.3 13.7 25.6 31.7 35.7 25.9 33.5 22.8 13.0 40.7 18.2 24.0 8.8 23.4 16.5 18.3 24.7 14.8 23.1 27.3 23.3 24.4 22.7 28.3 32.6 17.1 26.2 28.1 85.3 12.9 50.6 53.9 14.9 67.6 83.9 72.3 71.9 21.7 73.5 96.6 78.2 11.8 63.3 16.3 36.6 73.1 33.5 16.2 16.1 23.0 19.6 16.0 13.2 12.6 12.3 14.9 8.8 14.8 18.3 46.0 41.7 47.7 9.8 54.3 45.4 36.7 29.4 59.2 34.5 23.3 50.0 52.7 14.3 18.0 25.8 14.6 41.1 56.2 16.4 60.7 20.7 22.9 12.2 24.2 27.9 9.6 37.0 13.7 10.8 22.8 41.3 23.0 11.2 15.2 24.1 18.5 33.5 14.3 45.4 15.9 20.7 28.5 9.2 24.2 6.2 37.9 19.7 24.9 7.5 26.3 35.7 44.3 14.6 10.4 13.6 17.4 42.2 42.2 22.8 19.9 39.3 14.8 36.6 13.1 42.7 33.1 115.2 59.7 40.6 36.1 10.8 63.0 43.3 20.8 8.0 C12orf66 FLJ32549 ENSG00000174206 "Chromosome 12 open reading frame 66" Q96MD2 12 64186316-64222296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046743, HPA052855" Uncertain Supported "Lysosomes,Cytokinetic bridge" Yes No "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Lysosomes "Cytokinetic bridge" "HPA046743: AB_2679782, HPA052855: AB_2681973" "unprognostic (7.44e-3)" "unprognostic (2.38e-1)" "unprognostic (6.20e-2)" "unprognostic (2.70e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "unprognostic (3.45e-2)" "unprognostic (2.08e-1)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (1.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (7.46e-2)" "unprognostic (4.07e-2)" 2.9 4.2 3.6 3.4 5.3 1.7 5.4 4.0 4.8 2.8 1.9 2.8 3.1 2.6 4.8 4.2 3.9 2.5 2.3 3.5 4.3 5.5 8.6 2.8 4.9 4.0 4.4 3.9 5.2 5.7 2.6 2.1 4.5 2.3 3.1 1.6 2.9 2.3 4.4 5.6 2.5 2.3 3.7 5.0 3.0 3.4 4.3 3.3 5.6 3.2 4.8 2.6 3.0 6.8 5.5 8.7 1.6 4.7 4.3 7.2 4.5 3.0 3.7 4.4 2.7 2.7 4.3 17.4 4.1 2.4 7.1 6.3 6.9 5.3 4.7 13.3 4.6 6.3 2.1 2.5 5.6 6.9 3.6 5.6 9.0 5.7 10.3 5.0 3.2 12.0 8.8 11.3 4.4 10.6 7.9 6.0 7.7 6.5 6.8 4.0 4.9 13.4 6.6 6.4 3.8 3.8 4.9 6.7 4.8 4.2 10.8 4.4 2.5 4.4 2.9 4.4 2.9 14.9 13.2 9.7 6.6 5.9 5.0 0.5 2.6 0.2 3.3 2.6 5.7 8.5 6.4 5.0 4.3 7.2 8.7 8.4 0.2 4.0 1.8 3.1 10.8 4.2 3.6 5.3 4.0 4.8 3.5 4.3 4.0 4.4 4.5 3.7 4.3 6.8 3.4 3.2 2.7 5.5 9.3 2.4 8.8 3.4 7.4 2.1 5.9 4.1 2.7 7.2 5.5 9.2 2.1 6.3 4.0 1.9 9.8 4.1 9.2 3.3 4.0 3.9 4.2 3.4 7.1 5.2 3.9 3.5 7.1 3.6 1.3 3.6 1.8 10.8 4.9 0.0 5.5 2.7 4.1 6.3 2.6 7.3 4.7 4.3 1.8 1.0 2.1 2.5 1.0 3.5 17.4 2.6 2.6 1.9 2.8 4.7 2.1 12.9 2.4 1.6 0.0 7.4 2.8 4.4 8.8 6.9 4.3 1.8 5.8 4.3 3.7 4.3 C12orf73 "BRAWNIN, DKFZp547P055, FLJ13975" ENSG00000204954 "Chromosome 12 open reading frame 73" Q69YU5 12 103940763-103965708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 42.5" "Cell type enhanced" "Detected in many" "Early spermatids: 87.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038883 Uncertain Approved "Plasma membrane,Centrosome,Mitochondria" "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Centrosome, Mitochondria" "Plasma membrane" "HPA038883: AB_10794735" "unprognostic (9.24e-2)" "unprognostic (3.26e-3)" "unprognostic (3.66e-3)" "unprognostic (7.20e-2)" "unprognostic (3.28e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.98e-4)" "unprognostic (8.96e-2)" "unprognostic (1.86e-2)" "unprognostic (3.79e-2)" "unprognostic (3.03e-3)" "unprognostic (2.07e-1)" "unprognostic (1.33e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (6.27e-2)" "prognostic favorable (1.61e-4)" 6.0 11.4 15.6 7.7 15.4 4.4 7.9 17.1 16.1 8.5 13.3 7.2 7.0 8.2 10.3 6.4 7.3 4.6 12.3 15.5 16.7 10.3 8.3 5.8 9.2 14.7 15.0 10.1 7.7 10.0 10.8 6.1 15.2 8.7 7.6 13.2 7.2 7.3 42.5 8.3 6.8 6.5 14.4 6.9 8.9 10.9 15.3 8.3 12.9 27.6 8.9 7.3 6.9 17.3 11.8 21.2 31.8 19.4 8.9 11.6 20.7 12.6 7.4 13.4 10.8 23.2 9.9 13.7 15.9 7.5 11.7 18.3 19.1 15.6 10.1 19.7 38.4 20.9 32.9 29.1 13.1 30.8 18.2 10.3 17.6 6.9 11.9 32.5 12.5 39.5 27.0 9.2 12.5 13.2 34.5 46.1 15.6 11.0 35.9 19.7 11.9 13.7 17.8 16.6 51.8 18.5 13.0 21.9 29.7 14.1 36.4 16.7 6.5 16.4 9.3 12.4 12.8 24.5 40.6 28.8 22.4 17.4 14.5 10.1 5.6 10.6 11.7 5.0 11.4 14.6 10.6 11.1 8.6 11.3 15.7 14.8 1.7 14.5 4.5 13.3 17.0 4.2 15.6 15.4 17.1 16.1 15.5 16.7 14.7 15.0 15.2 14.4 15.3 17.3 6.8 6.4 6.8 7.5 7.8 6.0 9.4 16.3 18.8 16.3 9.0 11.0 16.5 7.2 10.0 9.2 0.0 11.6 8.6 7.1 27.4 20.3 87.1 8.7 10.3 8.3 11.4 18.5 5.0 12.1 11.7 7.9 15.3 9.1 9.5 13.8 8.9 15.5 17.5 8.4 6.0 13.2 20.3 7.9 5.1 36.6 8.7 8.7 1.8 2.8 12.4 17.1 22.6 7.5 9.0 19.9 5.6 8.6 13.7 13.7 16.0 25.9 10.9 15.2 6.6 5.6 11.7 31.1 25.6 16.0 5.3 8.9 8.8 6.4 12.3 8.6 C12orf76 FLJ40142 ENSG00000174456 "Chromosome 12 open reading frame 76" 12 110027028-110073634 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "brain: 77.2;choroid plexus: 44.0" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 174.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 60.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA039713 Uncertain Approved "Plasma membrane,Actin filaments" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 51: Myeloid cells - Hemostasis" "Actin filaments" "Plasma membrane" "HPA039713: AB_2676640" "unprognostic (9.20e-2)" "unprognostic (3.31e-2)" "unprognostic (2.35e-3)" "unprognostic (9.54e-2)" "unprognostic (3.50e-2)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "prognostic favorable (6.44e-5)" "unprognostic (1.39e-1)" "unprognostic (1.47e-1)" "unprognostic (8.86e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (5.74e-5)" "unprognostic (2.09e-1)" "unprognostic (7.85e-2)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" 4.0 5.0 58.2 5.4 61.5 2.4 7.4 67.2 76.0 6.8 44.0 6.2 3.5 5.6 9.9 3.9 10.3 3.7 4.0 59.5 61.6 8.4 10.1 8.0 8.5 64.9 63.6 8.4 6.4 3.9 10.2 8.0 67.3 6.7 4.7 16.6 5.0 5.1 6.7 4.6 5.7 3.4 60.0 9.2 4.6 8.3 61.3 7.1 9.6 4.1 6.1 5.5 5.4 77.2 3.8 7.5 10.7 8.8 5.2 12.2 10.9 3.4 3.0 7.3 5.0 4.8 4.3 8.1 4.6 1.8 5.0 8.8 4.2 5.4 5.0 9.8 9.9 8.5 7.2 13.3 7.2 13.6 16.2 13.7 14.9 4.7 11.3 19.7 10.7 13.4 13.0 3.0 5.4 4.1 4.3 25.2 9.4 5.1 6.1 10.5 7.0 12.5 11.2 4.1 26.4 12.5 5.3 2.8 11.1 13.3 8.4 6.2 6.2 3.5 4.9 3.4 1.5 8.4 12.8 4.4 8.2 6.3 3.5 60.0 10.2 11.0 6.4 7.8 9.2 18.6 12.7 7.1 10.9 11.6 17.4 10.2 5.8 18.8 5.2 9.7 12.8 12.0 58.2 61.5 67.2 76.0 59.5 61.6 64.9 63.6 67.3 60.0 61.3 77.2 22.5 32.1 17.0 13.4 15.2 7.9 16.2 18.7 13.6 26.4 24.9 39.8 7.1 18.6 10.5 16.5 2.1 30.2 13.3 6.4 35.2 11.6 31.0 42.3 18.7 18.3 6.1 14.5 32.0 15.1 10.5 17.7 6.6 17.4 5.1 22.8 21.8 22.4 26.4 32.0 28.5 10.7 16.2 24.2 13.1 13.5 26.1 35.9 19.6 15.0 25.3 39.4 24.7 53.3 174.6 11.8 7.5 33.8 10.2 11.7 13.3 38.6 33.9 20.9 6.6 16.4 16.5 25.2 11.3 9.0 8.5 12.0 21.8 15.4 9.5 9.8 C13orf46 ENSG00000283199 "Chromosome 13 open reading frame 46" A0A1B0GUA9 13 113953705-113974076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 9.5;stomach 1: 6.9;testis: 12.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 2.2;Exocrine glandular cells: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 1.1;RPMI-8226: 1.4;T-47d: 1.0;U-138 MG: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 11: Alveolar cells - Smell perception" 1.3 0.0 0.2 0.1 0.1 0.5 0.9 0.0 0.2 0.4 1.4 0.4 0.1 0.2 0.0 0.1 0.5 0.4 0.3 0.5 0.0 0.1 0.3 2.6 0.2 0.3 0.3 0.1 9.5 0.0 0.4 0.0 0.2 1.2 0.1 0.0 1.0 0.0 0.4 0.3 0.3 0.0 0.0 0.3 6.9 12.6 0.3 0.1 2.5 0.0 0.0 1.0 0.3 0.7 0.1 0.0 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.4 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.1 1.0 0.1 0.2 1.0 0.6 0.2 0.3 0.0 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.5 0.0 0.3 0.3 0.2 0.0 0.3 0.7 0.0 3.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 C14orf93 "FLJ12154, RTFC" ENSG00000100802 "Chromosome 14 open reading frame 93" Q9H972 14 22985894-23010166 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002569 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA002569: AB_1078334" "prognostic favorable (5.05e-4)" "unprognostic (1.31e-2)" "unprognostic (2.97e-2)" "unprognostic (2.23e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "unprognostic (4.86e-3)" "unprognostic (7.45e-2)" "unprognostic (2.01e-3)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (2.14e-1)" "unprognostic (7.11e-2)" 8.3 4.8 6.5 5.7 7.7 12.6 8.2 6.7 7.0 11.2 8.5 8.8 7.4 8.7 11.4 7.4 9.5 9.2 5.6 6.2 7.3 11.1 8.9 6.7 10.1 7.7 7.2 10.3 9.6 8.3 6.5 5.0 7.5 9.6 9.6 4.4 8.0 5.7 6.7 18.3 8.1 6.8 6.7 10.6 8.3 4.0 7.2 15.7 11.5 7.9 10.5 8.6 8.3 9.5 5.7 10.5 8.8 12.3 13.9 30.8 12.2 6.6 10.2 5.1 6.7 6.6 16.5 16.0 6.1 6.0 7.2 11.8 5.4 16.6 4.7 6.3 3.8 10.1 14.0 15.3 12.1 7.4 8.3 22.4 12.8 7.6 9.6 18.5 9.6 10.1 11.1 3.4 5.3 16.3 9.5 13.6 3.0 12.3 7.3 15.1 8.4 9.8 6.7 8.6 31.8 13.8 8.8 8.4 9.0 9.4 13.0 12.8 5.5 9.6 12.7 4.3 6.7 11.9 3.6 11.0 6.6 9.1 10.0 12.2 7.7 22.9 8.1 7.4 7.2 10.4 6.5 8.5 9.1 10.0 9.8 9.4 11.2 10.4 13.0 6.3 13.4 7.1 6.5 7.7 6.7 7.0 6.2 7.3 7.7 7.2 7.5 6.7 7.2 9.5 3.1 9.6 1.1 14.7 8.7 3.1 4.1 4.6 10.2 1.4 4.0 4.1 3.3 1.5 2.6 0.0 4.2 4.3 7.8 3.7 7.9 3.9 0.8 3.3 2.6 3.3 15.7 6.5 3.4 3.0 5.7 3.9 7.7 3.0 7.0 4.7 1.4 1.5 3.8 0.0 3.4 6.3 4.1 5.5 2.5 1.5 4.4 3.4 5.4 9.4 1.9 4.1 7.2 7.1 9.9 3.1 7.3 4.1 5.2 1.9 4.6 3.6 4.6 2.0 6.6 3.8 3.7 2.9 8.2 5.3 1.6 3.0 5.2 4.1 5.1 2.5 C15orf48 "COXFA4L3, MIR147BHG, NMES1" ENSG00000166920 "Chromosome 15 open reading frame 48" Q9C002 15 45430579-45448761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 924.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2962.4;Exocrine glandular cells: 2020.8;Langerhans cells: 2043.7;Pancreatic endocrine cells: 3493.6;Paneth cells: 2254.4;Proximal enterocytes: 2942.0;Undifferentiated cells: 1875.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;intermediate monocyte: 1.6;myeloid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 70.9;CAPAN-2: 128.8;GAMG: 126.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA012943 Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA012943: AB_2668774" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (7.83e-2)" "unprognostic (1.17e-1)" "unprognostic (9.74e-3)" "unprognostic (1.48e-3)" "unprognostic (1.28e-3)" "unprognostic (1.59e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-3)" "unprognostic (5.95e-2)" "unprognostic (8.86e-2)" "unprognostic (2.37e-1)" "unprognostic (6.51e-2)" "unprognostic (1.39e-1)" "unprognostic (3.66e-1)" 2.2 0.3 0.5 98.5 0.5 88.0 30.7 0.4 3.2 38.9 0.7 863.4 61.9 5.3 0.2 172.4 6.8 45.9 0.8 0.5 0.5 5.8 6.0 11.5 5.7 0.6 0.4 0.7 13.0 0.1 0.5 46.4 1.3 13.9 924.2 3.6 23.0 11.5 0.4 69.9 341.3 31.3 0.4 2.3 107.6 128.1 1.0 7.0 5.2 0.2 84.8 38.9 46.6 0.6 70.9 18.1 0.2 0.3 0.9 0.0 2.7 3.5 25.1 4.6 12.7 2.9 128.8 0.2 3.1 0.4 126.2 1.8 2.3 0.9 10.7 7.0 1.9 0.0 0.2 0.5 11.2 0.1 29.1 1.3 1.2 22.9 0.0 0.0 0.0 0.5 0.1 0.5 0.6 3.5 0.1 1.8 0.1 31.4 0.3 0.0 0.4 0.4 2.7 5.7 0.1 0.6 4.1 8.0 0.3 14.0 1.4 1.6 0.6 0.4 1.6 1.0 0.9 2.1 1.2 0.4 1.9 0.7 0.5 0.0 1.3 0.1 0.0 1.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.8 0.0 0.2 0.1 0.0 0.8 0.5 0.5 0.4 3.2 0.5 0.5 0.6 0.4 1.3 0.4 1.0 0.6 5.5 16.0 15.0 0.3 20.4 66.4 20.2 846.0 1.2 0.5 143.2 111.9 1.0 188.8 1117.6 5.5 0.0 286.2 7.4 2962.4 3.9 811.3 188.3 29.2 11.0 11.6 645.1 0.0 0.2 2020.8 450.3 16.4 250.2 67.7 33.0 0.2 1.4 3.7 398.4 114.4 0.1 1408.8 270.6 25.9 2043.7 235.4 7.2 388.4 58.7 0.0 489.4 0.7 1.0 0.5 0.4 3493.6 2254.4 7.5 4.1 200.5 2942.0 18.7 700.9 1.2 0.0 1.2 75.2 567.9 124.4 10.6 61.2 165.5 13.9 0.1 1875.4 633.4 C16orf74 MGC17624 ENSG00000154102 "Chromosome 16 open reading frame 74" Q96GX8 16 85690084-85751129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 27.7" "Cell type enhanced" "Detected in many" "B-cells: 47.4;Basal prostatic cells: 56.7;Bipolar cells: 55.8;Cone photoreceptor cells: 58.4;Rod photoreceptor cells: 87.8;Syncytiotrophoblasts: 74.3;Urothelial cells: 55.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 96.1;hTCEpi: 80.8;T-47d: 84.5" HPA049367 Uncertain Approved "Plasma membrane,Centrosome" NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "Plasma membrane" Centrosome "HPA049367: AB_2680730" "unprognostic (1.16e-1)" "unprognostic (2.21e-2)" "unprognostic (6.74e-3)" "unprognostic (2.15e-3)" "unprognostic (3.65e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.08e-3)" "unprognostic (4.22e-3)" "prognostic unfavorable (4.08e-4)" "unprognostic (5.06e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (3.40e-1)" "unprognostic (1.76e-3)" "unprognostic (2.51e-1)" "unprognostic (3.55e-1)" "unprognostic (2.15e-2)" "unprognostic (9.07e-3)" 3.6 0.7 8.4 4.3 8.5 8.9 6.5 6.8 12.0 9.5 7.8 3.1 1.4 1.5 2.0 9.4 1.5 2.2 2.2 12.2 7.4 2.5 1.1 2.2 8.4 7.5 7.4 0.8 1.8 7.5 1.3 6.7 7.0 9.2 1.1 27.7 4.2 7.3 0.5 9.0 5.6 0.9 6.7 16.0 2.9 2.1 7.6 1.4 5.0 0.3 6.4 17.2 14.5 7.4 35.3 11.5 0.4 4.7 5.1 5.6 14.1 4.2 5.6 13.1 3.7 8.9 32.1 0.3 47.2 3.3 5.5 49.4 2.0 96.1 7.4 0.0 7.6 0.0 5.3 0.9 13.9 1.0 0.0 12.2 80.8 12.6 54.7 9.8 43.4 5.8 0.0 0.2 0.4 29.6 0.0 54.0 2.9 37.7 32.6 1.4 0.0 2.8 0.1 39.5 10.7 2.8 17.5 8.9 9.1 3.6 84.5 14.9 44.8 8.4 22.0 3.8 12.7 11.7 9.3 40.0 0.0 12.6 1.7 0.1 16.8 21.8 1.3 6.3 4.4 46.7 8.8 7.0 18.3 49.4 14.5 9.3 6.6 7.8 2.0 0.3 18.0 10.8 8.4 8.5 6.8 12.0 12.2 7.4 7.5 7.4 7.0 6.7 7.6 7.4 10.1 3.2 1.1 6.5 47.4 9.3 56.7 23.8 8.0 55.8 19.0 20.3 1.8 1.5 9.8 1.8 58.4 45.8 3.4 0.1 3.9 3.0 1.7 4.4 4.6 7.2 0.0 0.8 0.4 1.1 19.7 5.7 1.5 4.1 0.0 0.5 2.5 0.0 5.0 15.2 0.4 0.0 8.2 1.2 2.9 0.4 3.4 2.5 19.6 1.0 5.2 18.8 4.1 1.5 0.8 3.2 0.0 3.4 44.2 36.5 0.0 2.4 3.9 87.8 0.0 0.3 2.5 0.9 8.4 8.5 7.0 74.3 3.7 1.5 0.2 55.7 C16orf89 MGC45438 ENSG00000153446 "Chromosome 16 open reading frame 89" Q6UX73 16 5044122-5066110 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 108.3;thyroid gland: 228.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 44.8;Alveolar cells type 2: 268.1;Club cells: 70.4;Distal tubular cells: 113.5;Fibroblasts: 43.8" "Group enriched" "Detected in many" 14 "lung cancer: 64.7;thyroid cancer: 145.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 2.3;Hep G2: 2.5;HHSteC: 1.3;NTERA-2: 1.7;U-2197: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013613, HPA016934" Enhanced "Secreted to blood" NA NA 1400000 "Cluster 38: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA013613: AB_1845584, HPA016934: AB_2732417" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.97e-1)" "unprognostic (6.29e-2)" "unprognostic (3.79e-2)" "unprognostic (1.48e-1)" "unprognostic (2.67e-2)" "unprognostic (1.01e-2)" "unprognostic (9.23e-2)" "unprognostic (2.65e-1)" "unprognostic (6.39e-2)" "unprognostic (3.25e-2)" "unprognostic (6.64e-3)" "unprognostic (3.53e-2)" "unprognostic (1.25e-1)" "unprognostic (5.54e-2)" "unprognostic (8.48e-3)" 17.8 4.2 20.0 6.0 21.6 0.2 12.8 18.8 28.3 20.2 15.0 6.3 17.6 3.5 87.1 6.7 12.4 45.0 18.8 19.4 19.9 16.8 0.3 108.3 0.9 19.9 18.5 2.8 5.4 0.1 5.7 0.9 19.0 4.2 5.0 0.5 35.0 1.1 0.2 0.6 7.9 4.9 19.6 0.6 82.4 1.2 22.6 2.8 228.8 3.9 2.2 14.4 3.2 22.7 0.0 0.1 0.0 0.2 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.6 2.5 1.3 0.1 0.2 0.6 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.1 0.7 0.3 1.7 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.5 0.3 0.1 0.0 0.0 0.2 0.1 2.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.2 0.0 0.1 0.0 0.0 20.0 21.6 18.8 28.3 19.4 19.9 19.9 18.5 19.0 19.6 22.6 22.7 0.9 44.8 268.1 23.2 0.0 0.4 1.8 0.3 0.6 0.5 23.6 18.0 2.8 0.0 70.4 0.0 0.0 0.1 0.1 0.1 113.5 0.0 1.7 3.7 0.4 1.3 0.0 0.0 0.9 7.8 0.1 43.8 17.3 0.3 5.1 0.0 0.0 0.0 6.0 0.0 0.7 0.6 6.1 0.0 0.4 2.7 9.3 0.7 0.0 11.2 0.0 0.3 0.0 1.0 1.6 0.7 0.4 14.7 0.0 5.0 0.0 1.5 16.9 0.2 0.0 1.9 1.9 0.8 0.1 0.6 0.3 0.3 0.6 0.0 0.7 5.0 C16orf90 LOC646174 ENSG00000215131 "Chromosome 16 open reading frame 90" A8MZG2 16 3493484-3495489 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 52 "testis: 48.3" "Group enriched" "Detected in some" 9 "Early spermatids: 246.4;Late spermatids: 501.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.96e-2)" "unprognostic (1.03e-3)" "unprognostic (3.17e-1)" "unprognostic (2.18e-1)" "unprognostic (1.08e-1)" "unprognostic (9.33e-2)" "unprognostic (1.20e-2)" "unprognostic (1.59e-2)" "unprognostic (6.29e-3)" "unprognostic (1.26e-1)" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 48.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 246.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 501.1 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C16orf95 ENSG00000260456 "Chromosome 16 open reading frame 95" Q9H693 16 87083562-87317420 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "testis: 101.4" "Group enriched" "Detected in many" 4 "Early spermatids: 94.6;Late spermatids: 96.2;Spermatocytes: 127.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA040850, HPA067924" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 74: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "HPA040850: AB_10794882, HPA067924: AB_2685924" "unprognostic (3.51e-1)" "unprognostic (1.95e-1)" "unprognostic (1.77e-2)" "unprognostic (4.30e-2)" "unprognostic (3.92e-2)" "unprognostic (4.60e-2)" "unprognostic (1.13e-1)" "unprognostic (2.45e-1)" "unprognostic (1.97e-2)" "unprognostic (1.09e-1)" "unprognostic (6.71e-2)" "unprognostic (1.79e-1)" "unprognostic (2.02e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (1.61e-2)" "unprognostic (1.23e-1)" 2.5 3.8 2.2 1.2 2.2 3.3 2.2 2.5 3.3 1.1 1.7 1.6 1.4 1.2 0.4 1.5 1.2 0.9 2.6 2.2 2.2 2.7 6.9 1.3 1.3 2.1 2.3 1.5 3.2 1.3 2.2 0.4 2.4 1.2 0.8 0.6 1.5 0.6 4.3 1.2 1.5 0.4 2.2 1.6 2.2 101.4 2.5 1.7 1.2 3.1 0.8 1.4 1.2 2.0 3.4 9.2 3.2 3.9 3.7 2.1 5.4 3.1 1.3 3.0 2.3 4.4 5.4 8.3 8.6 0.6 3.3 2.7 3.0 2.1 1.4 4.2 5.4 7.9 3.5 6.5 3.2 0.9 1.5 3.7 0.7 3.5 1.1 1.5 2.9 6.1 7.2 4.2 3.6 8.7 3.0 7.4 3.0 2.1 5.5 6.7 1.4 4.8 1.9 1.4 4.0 3.3 7.6 0.4 2.5 1.1 4.5 4.2 3.3 5.5 2.3 3.3 3.0 12.5 10.9 16.2 7.4 8.0 3.8 0.0 2.5 0.6 2.6 2.7 1.8 1.7 2.1 2.3 2.4 1.4 1.7 2.9 0.4 0.7 3.4 3.3 2.9 1.8 2.2 2.2 2.5 3.3 2.2 2.2 2.1 2.3 2.4 2.2 2.5 2.0 1.9 0.0 1.5 1.0 1.9 1.7 0.5 0.6 6.2 2.5 2.0 2.9 2.4 1.5 0.3 0.0 2.1 2.6 0.4 6.0 1.9 2.8 94.6 0.5 0.4 1.3 0.0 6.9 1.5 3.4 3.4 1.3 4.1 0.4 0.0 0.7 2.2 5.9 2.9 1.7 1.5 3.4 0.0 1.6 1.8 96.2 3.4 0.9 0.0 1.9 2.7 3.7 2.1 1.0 1.8 4.0 2.4 5.3 6.4 0.6 6.4 3.4 1.0 2.2 26.3 0.4 1.8 127.9 8.0 3.0 0.6 1.1 1.1 0.6 5.3 0.4 C17orf107 ENSG00000205710 "Chromosome 17 open reading frame 107" Q6ZR85 17 4899418-4902934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 16.6;pituitary gland: 27.0" "Cell type enriched" "Detected in many" 5 "Late spermatids: 288.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.0" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.9" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.9" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 2.6;HMC-1: 3.2;hTCEpi: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA069713 Uncertain Approved Nucleoplasm NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA069713: AB_2686181" "prognostic favorable (5.06e-5)" "unprognostic (1.63e-1)" "unprognostic (2.43e-1)" "unprognostic (1.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.13e-3)" "unprognostic (9.61e-2)" "unprognostic (5.03e-2)" "unprognostic (4.15e-1)" "unprognostic (2.05e-1)" "prognostic favorable (8.61e-4)" "unprognostic (1.17e-1)" "prognostic favorable (2.68e-4)" "unprognostic (9.29e-2)" "unprognostic (2.65e-1)" "unprognostic (2.71e-1)" "unprognostic (3.12e-1)" 2.2 1.8 1.3 1.1 0.9 2.1 2.0 9.0 3.6 2.1 0.0 0.9 1.0 1.5 3.4 1.1 1.8 1.5 16.6 1.7 3.5 2.9 5.6 2.0 0.5 1.3 0.2 4.2 5.0 3.6 27.0 0.6 0.7 3.4 0.4 1.7 13.2 1.9 0.5 3.5 1.0 0.4 0.0 2.0 3.3 4.6 1.6 0.3 1.3 0.0 0.6 1.0 1.6 1.0 0.3 0.4 0.5 0.1 1.0 0.8 0.7 1.9 0.2 0.1 0.3 0.3 0.3 0.2 0.3 2.6 0.0 0.7 0.0 0.2 0.1 0.0 0.4 0.8 0.4 0.4 1.4 0.0 3.2 0.8 3.3 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.9 0.4 0.1 0.1 1.4 0.1 0.1 0.0 0.2 0.2 1.0 0.1 0.2 0.3 0.5 0.2 0.1 0.3 0.2 0.2 0.2 0.3 0.0 0.2 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.0 0.0 0.0 0.1 1.3 0.9 9.0 3.6 1.7 3.5 1.3 0.2 0.7 0.0 1.6 1.0 1.7 0.0 1.3 1.6 9.7 1.8 2.8 0.4 6.8 1.2 3.5 1.7 14.4 0.0 1.1 0.0 0.0 0.4 4.5 0.1 1.9 0.4 53.3 0.8 0.4 1.5 0.0 0.0 0.7 1.3 2.3 2.3 2.0 1.2 11.4 0.9 0.4 3.1 1.0 5.0 0.8 1.5 2.0 1.9 10.7 288.4 1.5 6.3 1.8 0.0 0.1 0.0 0.0 0.0 0.2 0.7 0.0 1.2 8.1 2.3 0.2 1.9 0.6 0.8 0.0 0.5 2.0 1.5 1.2 1.2 1.3 5.2 4.0 1.1 0.2 1.1 C17orf58 ENSG00000186665 "Chromosome 17 open reading frame 58" Q2M2W7 17 67991099-67996469 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 35.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 55.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 37.3" HPA023036 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA023036: AB_10601144" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (6.66e-2)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (7.65e-3)" "prognostic unfavorable (8.99e-4)" "unprognostic (7.45e-2)" "unprognostic (2.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.22e-2)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.31e-10)" "unprognostic (1.16e-2)" "unprognostic (1.04e-1)" "unprognostic (5.00e-2)" "unprognostic (1.01e-1)" 11.9 5.4 5.2 2.8 5.5 3.9 16.9 5.4 10.0 26.8 4.8 8.4 4.0 15.1 6.9 5.1 7.8 4.7 5.9 5.7 5.3 6.1 9.4 3.4 3.2 5.4 5.3 4.8 4.8 3.2 2.0 35.6 5.1 5.8 7.3 8.9 4.3 3.6 3.5 3.5 4.6 10.9 5.5 2.3 6.8 3.0 5.2 2.1 6.8 7.3 7.1 8.8 7.6 5.5 9.8 9.5 9.3 11.6 6.6 16.6 7.3 4.0 11.4 6.9 11.2 5.6 12.4 13.0 8.9 3.3 12.1 4.9 21.3 8.6 16.6 23.5 21.5 8.4 3.2 17.8 10.4 7.2 14.9 9.2 10.2 6.7 15.4 7.7 32.7 11.2 18.2 19.6 6.7 13.1 1.3 9.5 10.7 23.6 10.0 3.1 10.2 17.4 8.7 6.5 6.9 12.5 6.0 55.5 20.8 11.4 15.8 8.2 6.1 5.8 5.9 4.2 8.5 38.9 30.9 11.6 14.8 12.6 10.5 8.6 2.8 5.0 2.2 2.9 0.7 3.0 0.8 1.7 3.9 0.5 0.3 0.8 1.1 2.7 5.0 0.1 0.4 1.8 5.2 5.5 5.4 10.0 5.7 5.3 5.4 5.3 5.1 5.5 5.2 5.5 21.6 0.0 1.7 6.2 3.5 4.8 5.5 5.6 7.4 8.9 31.0 21.8 4.7 12.8 6.1 11.0 10.4 28.6 4.1 10.5 23.5 10.1 0.9 21.0 40.5 16.3 3.6 8.4 5.0 9.3 21.7 51.6 19.9 19.4 12.7 3.8 14.3 18.5 16.9 5.0 4.6 15.0 10.2 9.7 21.5 2.8 3.7 7.3 8.8 2.8 18.4 31.9 12.3 3.0 4.6 10.7 10.0 5.3 7.0 11.6 10.9 19.7 16.5 15.6 6.6 36.2 14.1 7.3 6.0 20.7 8.4 15.3 4.1 8.3 10.1 7.6 C17orf67 ENSG00000214226 "Chromosome 17 open reading frame 67" Q0P5P2 17 56791913-56838773 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 9.5;MOLT-4: 14.6;PC-3: 9.7" "Region enriched" "Detected in single" 5 "olfactory bulb: 3.1" "Region enhanced" "Detected in many" "spinal cord: 15.6" HPA043479 Approved "Secreted to blood" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "HPA043479: AB_10964083" "unprognostic (2.78e-2)" "unprognostic (5.24e-2)" "unprognostic (1.83e-1)" "unprognostic (3.54e-3)" "unprognostic (1.69e-3)" "unprognostic (1.59e-2)" "unprognostic (2.10e-2)" "unprognostic (2.47e-1)" "unprognostic (4.63e-2)" "unprognostic (2.82e-3)" "unprognostic (9.64e-2)" "unprognostic (2.99e-2)" "unprognostic (1.68e-5)" "unprognostic (2.49e-1)" "unprognostic (3.27e-1)" "unprognostic (2.20e-2)" "unprognostic (1.43e-3)" 1.3 0.4 2.7 1.3 2.2 0.5 1.0 2.2 4.3 1.9 1.8 1.3 0.7 1.8 1.4 0.8 1.5 1.7 0.9 2.1 3.2 0.8 2.2 1.6 1.5 2.3 2.5 1.8 1.7 0.5 1.3 0.8 2.5 1.7 0.5 0.8 0.9 1.2 0.6 0.5 1.6 1.2 1.9 2.6 1.0 1.8 3.1 5.5 1.3 0.9 1.0 1.4 1.7 3.3 3.2 2.0 1.3 1.4 0.6 0.9 0.6 1.8 2.3 1.5 1.7 2.6 1.1 1.7 3.1 0.8 1.7 1.6 0.9 0.5 1.5 9.5 3.4 1.6 2.4 1.6 0.8 1.2 3.1 0.3 2.4 1.0 1.0 1.1 1.5 3.3 1.6 7.9 1.0 2.5 14.6 2.2 1.2 1.0 9.7 3.1 2.5 1.8 1.1 0.8 0.7 1.6 1.8 0.4 1.0 0.5 2.0 0.9 2.2 1.6 4.0 1.1 1.3 3.2 8.7 0.9 1.1 1.4 0.6 0.0 0.1 0.3 0.2 0.2 0.3 1.5 0.6 0.8 0.1 0.8 0.6 0.8 0.2 0.2 0.3 0.3 1.5 0.3 2.7 2.2 2.2 4.3 2.1 3.2 2.3 2.5 2.5 1.9 3.1 3.3 15.3 3.2 0.0 2.9 8.4 2.3 16.3 0.5 4.6 12.4 3.9 5.6 1.8 11.5 0.1 7.3 14.6 0.1 8.4 12.1 0.0 3.3 9.0 3.3 6.3 13.5 8.9 3.6 7.2 1.4 0.8 4.8 3.1 6.8 1.3 3.1 7.9 9.0 2.9 5.0 10.6 4.6 0.0 8.1 4.7 7.4 7.8 5.0 1.8 15.9 3.8 2.7 12.3 6.6 6.2 2.2 11.9 1.2 4.3 12.4 4.1 0.4 1.0 20.1 0.0 2.4 5.1 12.9 9.5 2.2 1.7 0.3 11.0 4.3 6.3 7.2 C17orf75 "NJMU-R1, SRI2" ENSG00000108666 "Chromosome 17 open reading frame 75" Q9HAS0 17 32324565-32350023 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 88.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004061, HPA075333" Approved Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Golgi apparatus, Cytosol" "HPA004061: AB_1078337, HPA075333: " "unprognostic (4.21e-2)" "unprognostic (2.49e-2)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (1.51e-1)" "unprognostic (4.73e-2)" "unprognostic (1.07e-3)" "unprognostic (6.36e-2)" "unprognostic (3.29e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.92e-2)" "unprognostic (7.80e-2)" "prognostic favorable (1.33e-4)" "unprognostic (3.09e-1)" "unprognostic (1.29e-1)" "unprognostic (4.27e-2)" "unprognostic (5.60e-2)" 8.1 15.9 10.9 10.4 11.4 7.5 13.2 12.1 13.5 8.9 12.3 11.7 13.3 12.4 18.7 8.7 15.0 7.0 19.4 10.8 11.7 21.3 14.5 8.7 12.9 11.2 10.9 16.1 13.2 27.8 13.4 10.4 11.8 11.6 12.6 26.1 12.2 10.6 17.5 7.2 10.8 10.4 10.5 9.5 12.9 26.3 11.1 16.0 14.1 14.3 13.2 9.6 8.2 11.2 39.2 33.4 51.0 15.5 13.3 14.5 27.9 25.5 22.4 34.3 29.1 18.2 14.9 23.5 28.6 18.2 52.6 42.5 32.8 27.6 46.6 18.0 37.9 18.7 39.8 39.5 26.6 26.3 14.1 13.4 33.0 25.2 17.4 28.6 25.3 43.6 38.9 31.8 22.8 29.2 76.5 26.9 37.7 23.9 14.7 50.1 31.5 44.0 21.4 18.2 50.4 44.3 21.1 19.1 62.7 37.2 50.4 16.8 19.8 18.8 35.4 9.3 42.4 42.5 51.0 82.9 15.3 23.0 5.7 34.6 12.4 16.4 17.6 12.0 20.1 18.2 16.9 18.3 16.1 19.9 18.2 17.0 3.2 19.0 17.1 12.8 19.6 15.4 10.9 11.4 12.1 13.5 10.8 11.7 11.2 10.9 11.8 10.5 11.1 11.2 12.6 12.8 30.7 7.2 13.8 5.9 13.4 27.8 12.5 25.0 11.3 13.5 25.8 8.6 19.3 14.7 8.4 31.8 10.7 3.8 43.0 16.2 10.0 17.2 8.8 10.5 12.6 13.5 11.1 13.8 18.0 9.8 9.7 10.5 11.4 18.3 6.4 11.0 9.7 32.0 15.0 8.0 28.5 7.5 3.7 6.3 7.5 7.8 5.4 2.8 6.7 17.5 11.3 10.1 8.7 11.8 3.2 8.2 14.0 6.4 6.9 29.9 29.9 23.0 39.5 9.7 13.1 88.0 31.8 12.0 6.1 16.3 15.1 10.5 8.4 8.2 C17orf99 "GLPG464, UNQ464" ENSG00000187997 "Chromosome 17 open reading frame 99" Q6UX52 17 78146353-78166177 "Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "bone marrow: 9.0" "Cell type enriched" "Detected in some" 29 "Erythroid cells: 52.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "HaCaT: 3.5;HMC-1: 7.1;K-562: 4.2" "Not detected" "Not detected" HPA029655 Uncertain "Secreted to blood" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA029655: AB_10601691" "unprognostic (3.55e-5)" "unprognostic (1.87e-2)" "unprognostic (2.06e-1)" "unprognostic (1.22e-1)" "unprognostic (1.88e-1)" "unprognostic (1.45e-3)" "unprognostic (1.47e-3)" "unprognostic (2.39e-1)" "unprognostic (3.86e-1)" "unprognostic (9.77e-2)" "unprognostic (2.05e-2)" "unprognostic (5.13e-2)" "unprognostic (1.38e-4)" "unprognostic (6.58e-2)" "unprognostic (4.72e-2)" "unprognostic (2.66e-1)" "unprognostic (5.78e-3)" 0.0 0.0 0.0 0.1 0.0 9.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 1.8 0.4 0.6 1.1 0.1 0.3 0.5 0.0 0.7 1.8 0.0 0.2 0.1 0.6 0.0 0.1 0.0 0.1 0.2 0.5 0.0 52.6 0.3 0.4 0.4 0.4 0.0 0.3 0.0 0.1 0.4 0.2 0.5 0.0 0.3 0.7 0.0 0.0 0.7 0.1 0.6 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.7 0.2 0.1 0.2 0.1 0.0 1.1 0.6 0.1 0.1 0.6 0.9 0.3 0.2 0.9 0.4 0.8 C18orf54 "LAS2, MGC33382" ENSG00000166845 "Chromosome 18 open reading frame 54" Q8IYD9 18 54357906-54385218 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 17.3" "Cell type enhanced" "Detected in many" "Early spermatids: 100.0;Extravillous trophoblasts: 24.0;Late spermatids: 29.7;Oligodendrocytes: 23.0;Spermatocytes: 38.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.8" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040704 Approved Nucleoplasm "Secreted in male reproductive system" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA040704: AB_10959454" "unprognostic (2.96e-1)" "unprognostic (5.58e-2)" "unprognostic (5.29e-2)" "unprognostic (8.63e-3)" "unprognostic (2.40e-1)" "unprognostic (1.05e-1)" "unprognostic (5.60e-6)" "unprognostic (1.11e-2)" "unprognostic (7.85e-3)" "unprognostic (2.55e-2)" "unprognostic (5.91e-3)" "unprognostic (1.13e-2)" "unprognostic (3.06e-5)" "unprognostic (2.29e-1)" "unprognostic (4.21e-1)" "unprognostic (1.28e-2)" "unprognostic (7.05e-2)" 2.1 0.6 1.7 2.3 3.5 1.3 1.1 2.6 2.4 1.9 0.6 1.4 0.8 2.3 0.4 1.0 0.9 1.1 0.9 1.5 2.4 0.8 0.4 1.3 3.0 3.4 2.7 1.4 0.2 0.6 0.2 3.1 3.3 0.6 1.3 1.2 0.4 0.8 0.3 1.0 0.8 1.8 2.3 1.7 0.8 17.3 2.6 3.5 0.9 1.2 2.7 1.0 1.0 5.0 10.2 6.6 22.8 11.7 5.8 10.0 8.2 16.0 6.8 15.5 19.6 4.4 5.2 6.9 4.3 5.6 6.4 9.7 16.9 9.3 20.1 26.5 5.2 7.8 7.2 6.1 1.3 9.4 8.0 3.4 1.8 20.9 10.6 6.7 21.6 9.6 7.8 15.6 22.6 3.8 9.7 4.7 12.5 1.6 11.2 7.7 18.3 5.3 7.1 6.9 14.4 7.8 7.0 2.6 4.2 11.7 4.7 6.8 17.5 32.0 13.3 5.3 8.8 9.8 11.8 10.6 8.1 14.5 22.4 0.5 0.2 0.0 0.4 0.3 0.3 0.3 0.3 0.2 0.2 0.4 0.3 0.3 0.0 0.2 1.8 0.1 0.7 0.2 1.7 3.5 2.6 2.4 1.5 2.4 3.4 2.7 3.3 2.3 2.6 5.0 3.9 0.0 0.6 1.6 1.1 0.4 0.7 0.8 0.0 2.2 0.9 0.9 1.5 0.0 0.2 1.8 0.0 0.9 2.3 0.6 0.0 0.2 100.0 1.4 2.3 3.2 0.0 11.2 0.6 0.2 24.0 2.9 0.5 0.8 0.0 14.2 3.6 0.3 2.5 0.0 0.7 0.4 0.0 3.1 2.1 29.7 1.5 1.7 1.8 3.7 1.3 2.4 3.1 4.5 23.0 0.4 0.9 0.7 1.9 0.5 0.2 0.3 0.3 0.9 0.0 2.1 3.0 38.4 14.5 0.8 0.4 2.1 1.2 0.9 1.7 0.8 C19orf12 "DKFZP762D096, MGC10922, MPAN, NBIA4, SPG43" ENSG00000131943 "Chromosome 19 open reading frame 12" Q9NSK7 19 29698886-29715789 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 118.9;tongue: 105.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046930 Approved Supported Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA046930: AB_10962836" "unprognostic (1.76e-1)" "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (1.01e-2)" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (1.54e-1)" "unprognostic (9.94e-3)" "unprognostic (7.93e-3)" "unprognostic (5.27e-2)" "unprognostic (1.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (3.22e-1)" "unprognostic (1.22e-3)" 118.9 25.3 22.1 14.4 25.8 4.4 40.8 16.6 24.8 13.8 12.6 16.8 19.5 14.3 9.0 13.2 12.8 12.9 30.9 23.9 22.7 20.8 69.3 11.3 21.2 20.5 20.3 14.7 17.1 15.4 14.5 13.2 21.7 14.1 9.3 8.5 18.1 12.4 62.2 14.7 17.6 13.4 16.8 16.0 12.9 7.3 23.1 14.1 10.7 105.5 13.6 15.2 11.7 19.9 19.9 39.4 18.4 23.2 45.0 27.5 28.8 23.1 22.7 22.5 29.2 19.1 8.1 16.1 24.1 29.1 20.4 8.5 15.7 9.5 15.1 42.8 28.3 18.0 13.5 33.2 25.1 14.0 22.8 31.8 20.2 13.7 10.9 18.0 20.1 9.8 14.0 20.3 23.7 13.8 9.9 10.1 11.1 17.3 9.9 19.2 19.1 12.3 17.2 20.1 11.3 23.8 13.9 17.8 37.0 18.8 7.6 15.4 20.9 47.4 37.0 19.5 21.2 28.4 27.1 12.0 28.3 8.4 20.3 1.1 2.3 1.4 16.0 2.5 9.4 4.6 9.1 11.6 2.2 3.6 9.2 11.5 2.8 7.1 2.7 5.0 11.9 8.0 22.1 25.8 16.6 24.8 23.9 22.7 20.5 20.3 21.7 16.8 23.1 19.9 9.6 12.8 13.7 9.4 13.7 12.7 11.1 8.2 14.8 15.8 13.2 9.4 30.1 2.8 7.3 9.2 6.2 29.2 21.7 9.2 15.6 17.1 1.8 8.5 16.0 10.4 3.6 9.5 19.5 23.1 25.5 20.0 8.2 8.8 16.5 16.2 14.6 62.4 15.6 5.0 18.3 7.5 8.2 12.5 9.9 1.8 28.9 8.7 10.6 8.4 20.1 15.8 41.2 12.1 17.4 20.0 11.0 29.3 20.7 12.8 24.0 37.5 6.6 9.6 6.6 24.6 13.3 4.6 5.3 10.1 7.7 21.9 21.6 23.8 8.2 7.8 C19orf47 FLJ36888 ENSG00000160392 "Chromosome 19 open reading frame 47" Q8N9M1 19 40319536-40348527 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "heart muscle: 90.0;skeletal muscle: 259.4;tongue: 139.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 45.2;Late spermatids: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 29.0" "Lineage enriched" "Detected in all" 10 "granulocytes: 29.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041843, HPA046309" Enhanced Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA041843: AB_10959886, HPA046309: AB_10960266" "prognostic favorable (6.50e-4)" "unprognostic (1.35e-3)" "unprognostic (1.80e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (2.75e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (1.41e-4)" "unprognostic (2.26e-1)" "unprognostic (1.59e-1)" "unprognostic (1.63e-1)" "unprognostic (1.47e-2)" "unprognostic (3.25e-2)" "unprognostic (6.23e-2)" "unprognostic (1.62e-2)" "unprognostic (5.28e-2)" "unprognostic (2.77e-1)" "unprognostic (3.28e-2)" 6.7 5.9 16.0 6.6 16.1 8.3 8.3 11.6 14.7 8.6 1.8 7.6 5.6 7.7 4.0 12.6 6.0 3.5 90.0 12.2 10.0 5.8 7.7 6.4 7.6 15.4 15.0 6.7 5.2 6.6 7.5 6.5 14.0 8.8 2.9 2.5 10.5 6.4 259.4 12.3 6.0 3.9 13.1 7.4 6.2 26.5 13.9 7.3 6.9 139.1 4.4 8.5 8.7 17.1 20.3 30.5 12.7 13.8 7.4 6.6 17.4 20.6 9.3 19.1 22.9 25.5 8.3 23.5 11.1 9.7 10.0 9.9 15.5 18.9 7.9 29.1 19.1 19.3 18.2 19.6 5.5 19.5 11.9 6.6 11.0 25.6 9.0 5.1 11.7 21.5 24.0 13.4 15.9 19.9 29.4 11.0 8.2 16.2 11.5 28.8 20.7 11.8 6.1 17.6 16.2 13.2 22.1 20.5 8.1 7.4 12.2 15.9 15.7 23.7 16.6 16.2 28.4 16.0 24.2 24.1 10.1 18.6 16.7 29.0 2.2 6.6 1.6 2.0 2.0 2.0 3.0 2.7 2.1 2.5 2.0 1.4 7.3 2.5 2.3 2.1 2.3 2.1 16.0 16.1 11.6 14.7 12.2 10.0 15.4 15.0 14.0 13.1 13.9 17.1 2.6 3.2 2.8 9.1 2.6 4.8 3.2 2.6 4.0 3.1 4.9 5.0 45.2 2.8 2.3 0.0 2.1 11.0 1.5 3.6 0.0 3.5 12.5 2.5 2.3 4.3 3.6 1.7 19.2 4.7 13.8 6.2 2.6 2.7 4.5 3.6 5.7 5.0 6.6 3.3 15.4 3.4 0.0 6.2 4.1 27.4 1.8 2.8 5.4 8.4 3.3 2.9 3.1 9.5 11.2 4.4 1.4 6.8 6.5 2.0 2.8 2.8 1.3 2.0 6.6 7.1 3.8 18.2 6.3 4.1 7.0 15.9 3.3 1.4 2.4 1.8 C19orf53 "HSPC023, LYDG10" ENSG00000104979 "Chromosome 19 open reading frame 53" Q9UNZ5 19 13774456-13778773 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059928, HPA061291" Approved Approved Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "HPA059928: AB_2684165, HPA061291: AB_2684469" "unprognostic (3.94e-2)" "unprognostic (2.70e-3)" "unprognostic (6.53e-2)" "unprognostic (3.12e-1)" "unprognostic (1.99e-2)" "unprognostic (8.93e-2)" "unprognostic (2.93e-3)" "unprognostic (2.77e-2)" "unprognostic (1.32e-1)" "unprognostic (2.96e-2)" "unprognostic (1.67e-1)" "unprognostic (6.31e-2)" "unprognostic (1.60e-3)" "unprognostic (5.21e-2)" "unprognostic (4.06e-2)" "unprognostic (2.69e-3)" "unprognostic (1.85e-2)" 95.6 117.7 154.3 52.1 157.8 80.4 88.9 161.0 209.6 97.0 148.4 94.3 45.4 91.6 85.6 92.3 87.6 49.8 155.6 154.4 163.8 124.4 111.0 80.1 76.9 159.4 159.9 111.7 95.5 92.8 111.6 40.2 157.8 98.8 41.6 35.7 76.9 52.8 167.6 95.2 72.4 63.0 157.5 82.1 91.2 51.6 158.0 101.5 90.4 107.2 70.8 88.6 82.6 157.3 176.4 249.9 123.0 98.9 169.6 191.1 80.1 167.0 145.5 201.0 200.7 235.8 83.5 95.4 198.2 202.4 146.6 90.1 111.6 250.1 102.7 113.5 362.3 90.1 254.6 260.5 174.9 140.7 109.4 237.8 174.7 188.1 105.9 129.0 171.0 136.6 140.9 154.2 157.9 406.2 193.6 145.9 152.6 133.8 441.8 105.7 94.9 160.5 177.1 221.3 108.6 132.4 115.1 130.8 172.5 89.2 120.0 139.0 118.4 221.9 89.2 239.4 227.5 172.3 240.3 144.4 132.3 157.6 121.8 264.1 220.1 275.7 211.0 238.2 240.4 333.2 270.7 248.4 202.2 321.1 318.1 289.7 107.1 184.7 214.3 289.4 337.9 496.3 154.3 157.8 161.0 209.6 154.4 163.8 159.4 159.9 157.8 157.5 158.0 157.3 167.0 115.4 97.8 13.7 205.2 291.1 260.1 349.2 147.4 50.5 258.7 352.9 263.3 213.1 207.8 268.5 22.9 218.6 176.5 230.1 628.0 242.5 176.8 229.3 189.8 194.4 227.3 174.0 10.5 335.2 406.3 184.4 109.6 233.0 128.7 132.4 179.9 367.5 368.2 35.3 10.2 254.3 236.0 247.1 287.1 621.4 218.7 187.5 231.3 5.6 338.9 220.3 260.6 6.6 18.8 269.6 272.8 182.4 164.1 360.5 353.9 820.0 189.3 65.9 92.1 138.5 206.0 102.6 137.0 187.7 348.5 213.0 216.0 169.8 257.5 345.2 C1GALT1 "C1GALT, T-synthase" ENSG00000106392 "Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1" Q9NS00 7 7156934-7248616 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 204.3;Syncytiotrophoblasts: 204.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "LHCN-M2: 288.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011294, HPA012819" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 43000 "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear bodies, Cytosol" "HPA011294: AB_1845623, HPA012819: AB_1845624" "unprognostic (1.52e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (7.38e-2)" "unprognostic (8.78e-2)" "unprognostic (2.97e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (1.42e-5)" "unprognostic (2.03e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.40e-1)" "unprognostic (2.83e-1)" "unprognostic (3.28e-1)" "unprognostic (8.28e-2)" "unprognostic (1.08e-1)" "unprognostic (1.33e-1)" 12.9 7.2 12.8 14.2 17.7 37.7 16.6 16.1 15.5 18.5 25.0 15.2 29.4 5.6 6.4 21.6 16.2 16.6 12.6 11.3 13.7 30.8 22.0 15.0 19.1 17.7 15.6 4.6 6.1 45.8 8.6 27.0 17.7 5.1 18.0 23.6 23.3 6.8 7.5 8.8 19.3 7.3 17.9 15.5 22.4 7.3 14.2 14.3 12.5 11.3 14.0 13.0 7.3 24.6 63.5 25.9 9.6 16.0 28.1 57.0 28.0 71.5 60.7 32.4 51.1 20.0 63.9 33.4 17.0 31.7 93.5 18.3 14.0 27.5 58.3 15.1 8.1 31.1 15.9 62.3 28.1 34.3 13.2 44.0 20.0 75.7 70.0 47.4 30.3 29.9 61.0 19.9 288.7 10.5 8.8 22.8 51.7 47.8 20.3 29.6 53.1 19.3 46.6 32.4 9.9 27.2 46.9 57.0 52.8 57.5 15.6 19.6 30.4 55.2 76.7 74.7 31.3 34.4 28.7 32.9 36.9 42.9 55.8 56.0 12.9 38.4 17.7 20.2 19.7 20.4 16.6 20.6 15.1 16.6 17.7 19.4 29.1 22.7 34.0 16.4 16.2 14.1 12.8 17.7 16.1 15.5 11.3 13.7 17.7 15.6 17.7 17.9 14.2 24.6 23.2 41.7 54.2 32.3 57.1 26.3 17.0 48.4 29.0 28.1 24.5 10.8 24.0 25.8 40.6 18.4 33.3 91.9 44.8 29.9 5.9 29.1 17.2 28.4 8.7 12.7 15.6 49.7 44.3 25.3 81.1 26.0 41.3 31.7 12.0 36.2 13.9 23.5 38.2 47.1 42.5 18.8 30.5 21.1 20.5 19.9 6.5 33.0 23.2 65.6 21.9 22.9 49.4 52.3 204.3 46.2 22.6 6.4 43.2 14.5 27.7 40.0 29.7 34.8 6.6 17.2 15.3 16.6 35.6 46.4 19.5 204.8 39.6 8.9 26.7 25.7 C1orf127 FLJ37118 ENSG00000175262 "Chromosome 1 open reading frame 127" 1 10946471-10982037 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 4.4;skeletal muscle: 16.5" "Cell type enriched" "Detected in some" 9 "Enteroendocrine cells: 20.4" "Cancer enriched" "Detected in single" 9 "pancreatic cancer: 2.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.3" "Lineage enhanced" "Detected in single" "dendritic cells: 1.3" "Cell line enriched" "Detected in single" 4 "THP-1: 2.6" "Not detected" "Not detected" HPA027654 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear speckles, Cytosol" "HPA027654: AB_10611814" "unprognostic (1.82e-2)" "unprognostic (8.57e-2)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.17e-2)" "unprognostic (2.03e-2)" "unprognostic (3.81e-2)" "unprognostic (1.32e-2)" "unprognostic (9.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.82e-2)" "unprognostic (8.47e-2)" "unprognostic (1.59e-2)" "unprognostic (3.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.04e-1)" "unprognostic (4.03e-1)" 0.2 0.6 0.3 0.1 0.3 0.1 0.1 1.2 0.7 0.1 0.2 0.3 0.7 0.0 0.1 0.6 0.0 0.3 0.6 0.2 0.3 0.0 0.2 0.4 0.6 0.2 0.5 0.0 4.4 0.1 0.2 0.2 0.3 0.1 0.6 0.0 0.2 0.0 16.5 0.0 0.3 0.0 0.2 0.6 1.9 0.5 0.7 0.1 0.2 3.7 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.3 1.2 0.7 0.2 0.3 0.2 0.5 0.3 0.2 0.7 0.3 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.3 0.8 0.0 0.8 0.6 0.1 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C1orf159 FLJ20584 ENSG00000131591 "Chromosome 1 open reading frame 159" Q96HA4 1 1081818-1116361 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.9" "Cell type enhanced" "Detected in many" "Early spermatids: 60.9;Late spermatids: 124.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010019, HPA075399" Approved Approved "Nucleoli rim,Mitotic chromosome,Intermediate filaments" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim, Mitotic chromosome" "Intermediate filaments" "HPA010019: AB_1078885, HPA075399: " "unprognostic (2.79e-1)" "unprognostic (9.46e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-1)" "unprognostic (2.60e-3)" "prognostic unfavorable (9.58e-6)" "unprognostic (1.34e-1)" "unprognostic (3.09e-1)" "unprognostic (2.04e-2)" "unprognostic (9.29e-2)" "unprognostic (3.26e-3)" "prognostic unfavorable (1.77e-6)" "unprognostic (4.10e-2)" "unprognostic (1.81e-1)" "unprognostic (7.56e-2)" "prognostic favorable (1.62e-4)" 4.0 4.8 9.6 1.6 8.0 2.4 3.8 0.9 10.4 5.3 3.2 6.1 1.8 4.2 1.1 8.6 4.8 2.2 4.3 9.4 1.0 7.7 6.7 3.9 1.8 6.3 2.7 4.3 3.7 0.7 5.3 1.4 2.8 6.9 0.6 1.6 4.6 2.3 2.2 5.0 4.1 0.5 0.7 5.5 6.0 22.9 5.4 1.8 4.5 0.3 0.9 5.5 5.9 6.9 15.7 12.0 5.6 10.0 1.5 1.6 13.3 9.0 2.1 7.8 5.1 6.5 14.7 4.3 10.8 2.8 6.4 12.2 2.5 7.1 2.2 8.6 18.2 3.1 19.6 7.0 3.6 5.5 7.3 3.2 2.8 3.3 1.6 2.3 3.8 6.4 18.6 3.1 2.8 11.9 10.2 13.2 4.7 5.9 19.7 12.0 6.7 8.5 4.7 4.7 11.8 16.1 6.8 12.2 7.6 1.6 7.8 6.5 5.2 8.3 8.8 11.9 9.2 5.6 8.3 7.8 6.8 14.9 6.5 8.1 2.6 1.4 2.6 2.6 2.8 2.5 2.5 3.0 1.7 2.2 2.5 2.6 0.5 2.7 1.8 2.2 0.9 2.3 9.6 8.0 0.9 10.4 9.4 1.0 6.3 2.7 2.8 0.7 5.4 6.9 6.3 0.0 7.7 20.2 3.4 7.5 3.6 6.2 4.6 5.9 8.9 6.6 2.3 5.7 7.1 9.2 4.2 5.0 4.9 13.6 1.9 8.2 60.9 8.6 8.2 4.4 4.2 5.2 26.5 7.0 14.0 4.2 20.4 9.0 5.7 9.0 3.3 5.3 3.9 13.5 21.8 7.4 6.1 1.0 4.8 124.1 2.8 3.9 3.6 2.8 6.0 3.2 9.2 10.6 24.5 7.8 3.5 1.5 6.9 5.1 3.4 1.8 10.4 8.2 0.0 3.5 4.8 18.3 6.8 4.2 7.0 4.9 4.6 4.4 9.4 4.9 C1orf198 "DKFZp667D152, FLJ14525, FLJ16283, FLJ38847, MGC10710" ENSG00000119280 "Chromosome 1 open reading frame 198" Q9H425 1 230837119-230869589 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 131.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 13.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 13.1" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 138.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004798 Approved Supported Cytosol "Intracellular and membrane" NA NA 80000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA004798: AB_1848722" "unprognostic (7.44e-2)" "unprognostic (1.89e-1)" "unprognostic (1.17e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-2)" "unprognostic (2.46e-1)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (2.32e-1)" "unprognostic (3.75e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.50e-5)" "unprognostic (3.53e-2)" "unprognostic (4.95e-2)" "unprognostic (1.38e-1)" "unprognostic (3.77e-2)" 39.7 13.4 77.5 11.0 106.4 5.3 30.0 93.3 83.7 36.5 41.1 35.2 11.8 38.8 14.9 14.9 32.7 32.3 45.4 72.6 85.0 17.3 14.7 66.9 15.5 108.4 105.1 27.3 27.9 20.1 7.6 31.1 108.9 21.4 11.4 9.8 23.4 32.3 106.2 34.0 13.9 46.1 97.8 18.0 29.9 6.8 94.5 6.6 34.9 26.1 9.1 33.2 26.4 131.3 22.4 16.7 44.9 30.8 81.9 59.9 76.7 40.4 63.7 20.4 20.6 53.0 12.3 26.8 24.5 138.1 10.3 14.1 23.5 8.9 15.0 87.5 22.3 4.2 15.0 17.9 35.7 13.9 4.0 72.9 13.4 8.1 8.9 43.7 12.9 16.9 8.7 9.0 14.1 15.0 11.0 6.6 52.6 49.5 13.7 25.6 32.1 6.0 16.2 26.7 26.0 41.5 20.5 27.2 14.2 23.6 34.6 11.8 10.3 32.9 32.8 7.7 24.5 16.0 7.7 8.0 8.7 8.7 95.3 13.1 1.3 0.3 2.0 2.7 2.4 1.9 1.3 0.8 1.7 1.2 2.6 2.3 1.0 2.9 1.3 0.2 0.6 4.7 77.5 106.4 93.3 83.7 72.6 85.0 108.4 105.1 108.9 97.8 94.5 131.3 11.1 192.3 23.2 35.3 1.2 26.0 13.1 6.4 7.4 2.0 32.7 23.7 36.4 32.9 17.3 11.0 10.4 17.5 1.3 2.6 1.9 41.9 11.4 8.2 8.9 11.6 5.4 9.9 2.6 26.3 32.2 33.2 3.6 10.6 2.5 15.1 8.6 4.5 11.0 25.2 5.3 9.0 8.2 1.8 19.4 8.3 13.4 11.6 65.8 13.1 3.6 12.8 0.0 6.0 67.5 31.1 3.7 9.1 2.5 21.3 2.8 7.4 12.2 4.6 32.9 26.8 45.1 10.4 5.7 8.9 29.0 12.9 3.4 5.2 6.9 18.7 C1orf226 FLJ13137 ENSG00000239887 "Chromosome 1 open reading frame 226" A1L170 1 162378841-162386812 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 21.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 29.2;Early spermatids: 22.7;Hepatocytes: 30.0;Late spermatids: 38.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 14.0;HEL: 18.4;OE19: 16.0" "Low region specificity" "Detected in all" "HPA052251, HPA074060" Approved Approved Nucleoplasm NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA052251: AB_2681775, HPA074060: " "prognostic favorable (2.60e-4)" "unprognostic (1.30e-1)" "unprognostic (2.69e-2)" "unprognostic (1.59e-2)" "unprognostic (6.71e-3)" "unprognostic (9.80e-2)" "unprognostic (8.55e-2)" "unprognostic (1.65e-1)" "unprognostic (2.05e-1)" "unprognostic (4.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-3)" "prognostic favorable (4.44e-5)" "unprognostic (9.34e-3)" "unprognostic (1.06e-1)" "unprognostic (1.51e-1)" "prognostic favorable (1.13e-4)" 1.9 9.6 3.5 1.1 3.6 2.0 8.1 4.6 3.1 3.8 5.1 9.3 5.6 2.4 2.4 4.1 3.2 3.4 3.4 3.7 5.1 11.3 21.9 2.5 0.4 7.2 4.0 1.2 3.7 4.0 9.9 2.4 5.3 4.8 9.7 7.0 8.5 7.7 0.6 5.2 7.9 2.4 5.8 0.6 8.7 4.0 3.5 0.4 0.8 0.6 1.5 2.5 2.2 7.3 14.0 0.9 13.1 8.9 0.4 0.0 0.2 0.9 1.4 0.8 0.5 2.0 7.2 0.0 9.5 0.3 4.7 10.3 3.7 0.9 0.7 0.1 4.4 18.4 0.8 10.2 0.3 0.0 0.0 1.4 1.1 0.0 0.5 3.9 3.2 2.3 1.7 0.1 0.2 5.6 0.5 0.0 6.3 16.0 7.5 0.3 2.2 0.0 12.1 7.0 5.9 3.7 4.6 1.6 3.1 5.3 5.7 0.9 3.1 0.1 1.4 0.1 4.0 6.3 0.0 0.0 2.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.6 4.6 3.1 3.7 5.1 7.2 4.0 5.3 5.8 3.5 7.3 2.5 3.2 2.6 0.3 0.1 0.8 1.7 1.1 0.6 0.8 10.3 14.9 3.4 4.3 2.4 14.7 29.2 0.1 0.1 11.6 0.0 0.9 22.7 2.6 1.1 2.2 2.4 0.0 2.8 2.3 0.1 0.7 0.0 4.2 0.0 3.4 4.2 30.0 0.1 6.7 1.8 11.6 4.1 1.0 0.7 38.4 2.1 0.1 0.0 3.7 0.0 5.0 0.0 6.6 3.7 1.7 3.6 1.9 0.0 2.6 7.7 0.2 2.7 0.4 0.0 0.2 0.6 1.1 0.9 0.6 1.4 0.1 0.3 0.5 7.1 2.5 C1orf54 FLJ23221 ENSG00000118292 "Chromosome 1 open reading frame 54" Q8WWF1 1 150268200-150280916 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Endothelial cells: 101.3;Kupffer cells: 145.7;Langerhans cells: 282.7;Leydig cells: 95.1;Peritubular cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "myeloid DC: 103.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 103.5" "Cell line enhanced" "Detected in many" "AF22: 77.8;AN3-CA: 110.5;ASC diff: 86.1;ASC TERT1: 141.3;HSkMC: 102.1;HUVEC TERT2: 108.4;U-87 MG: 68.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA026518, HPA043874" Approved Approved "Plasma membrane" "Secreted to blood" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA026518: AB_1845647, HPA043874: AB_2732511" "unprognostic (4.64e-3)" "unprognostic (6.81e-3)" "unprognostic (4.01e-3)" "unprognostic (5.69e-3)" "unprognostic (2.22e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-2)" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.16e-2)" "unprognostic (8.06e-2)" "unprognostic (1.33e-2)" "unprognostic (4.48e-2)" 37.6 19.1 59.8 26.4 60.7 11.9 30.7 62.0 96.2 27.6 56.2 25.9 13.3 30.1 39.1 17.9 33.2 46.4 34.6 57.6 62.2 28.4 29.7 29.2 62.6 61.9 61.8 7.9 5.1 14.5 10.5 59.2 62.0 28.7 25.9 16.2 8.4 75.6 24.6 11.1 15.0 60.3 63.5 69.4 12.7 13.9 64.2 30.8 13.9 48.3 27.9 36.2 18.2 62.4 1.6 0.3 77.8 110.5 86.1 141.3 2.2 14.0 20.5 3.8 12.0 0.9 1.9 0.6 4.1 12.3 1.5 2.7 0.2 0.5 5.6 1.4 12.2 1.9 2.0 1.3 17.7 3.9 2.6 102.1 5.9 24.8 1.9 13.2 108.4 1.8 1.8 12.2 15.0 4.2 0.7 24.0 5.7 0.1 3.9 18.8 1.7 1.4 1.1 6.1 1.5 1.3 1.4 0.8 7.5 16.4 1.4 58.0 0.7 28.1 2.1 0.8 0.9 5.0 4.8 1.2 68.3 3.1 0.7 0.1 21.2 0.8 0.6 20.8 2.5 0.9 3.8 1.7 103.5 0.7 3.5 2.0 1.0 0.8 5.6 2.1 1.9 6.4 59.8 60.7 62.0 96.2 57.6 62.2 61.9 61.8 62.0 63.5 64.2 62.4 115.7 3.2 4.5 19.6 3.3 6.4 2.2 2.4 1.8 0.8 2.3 3.7 10.6 2.8 2.5 22.0 0.0 1.3 1.5 2.0 76.3 0.7 9.4 3.1 37.6 101.3 1.2 0.4 4.1 2.3 0.8 29.3 5.1 3.1 1.3 0.7 51.8 1.3 45.3 0.0 3.8 1.3 0.0 145.7 282.7 19.6 95.1 65.6 12.4 16.9 24.9 23.4 1.0 0.5 0.3 2.0 1.5 104.2 3.0 4.9 2.7 4.9 0.5 1.6 32.9 7.5 70.4 16.6 1.9 7.5 5.1 3.6 3.3 5.2 1.4 8.4 C1orf56 "FLJ20519, MENT" ENSG00000143443 "Chromosome 1 open reading frame 56" Q9BUN1 1 151047751-151051986 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 76.5" "Cell type enhanced" "Detected in all" "dendritic cells: 213.9;Early spermatids: 440.4;Langerhans cells: 245.2;Spermatocytes: 308.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 15.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037429, HPA037430" Enhanced "Secreted to blood" NA NA 87000000 "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "HPA037429: AB_10671755, HPA037430: AB_2675473" "unprognostic (7.60e-2)" "unprognostic (8.26e-2)" "unprognostic (1.09e-2)" "unprognostic (3.83e-1)" "unprognostic (4.31e-2)" "unprognostic (2.83e-2)" "unprognostic (1.11e-2)" "unprognostic (3.81e-3)" "unprognostic (1.59e-2)" "unprognostic (2.70e-3)" "unprognostic (3.28e-3)" "unprognostic (5.29e-2)" "unprognostic (3.61e-2)" "unprognostic (3.61e-2)" "unprognostic (6.16e-2)" "unprognostic (2.26e-1)" "unprognostic (4.79e-2)" 4.6 10.2 2.1 1.5 2.9 0.6 4.4 3.3 2.5 5.7 3.1 4.9 2.1 5.3 3.2 5.4 5.7 2.6 7.9 1.9 2.2 6.5 8.3 2.9 1.6 2.9 2.8 5.9 7.6 3.4 10.0 1.2 2.6 6.4 0.7 1.9 5.5 3.1 6.5 4.2 3.5 1.2 2.9 4.3 5.5 76.5 2.4 0.4 8.2 2.3 0.4 5.1 5.0 3.2 4.1 8.0 2.7 1.2 4.4 4.2 2.4 2.2 3.2 1.4 1.1 3.5 5.6 0.9 3.5 2.4 3.0 5.3 1.5 0.3 0.8 5.2 1.7 1.0 5.9 4.3 3.0 1.1 0.9 3.1 1.7 2.1 0.8 2.7 2.1 1.7 2.2 2.1 1.3 15.9 1.5 2.8 4.5 3.2 4.4 1.3 2.7 2.9 1.2 2.3 3.6 7.0 7.0 3.7 5.5 5.0 7.3 3.0 2.2 1.9 3.3 5.1 2.0 4.7 4.0 12.2 3.5 0.6 2.4 223.6 22.7 50.4 90.8 54.5 70.3 46.7 78.6 80.8 19.7 51.7 64.8 90.8 69.8 59.0 48.2 28.1 48.9 4.1 2.1 2.9 3.3 2.5 1.9 2.2 2.9 2.8 2.6 2.9 2.4 3.2 57.6 6.4 10.1 19.2 56.8 64.6 38.1 20.8 4.6 20.2 80.3 46.2 7.1 40.0 17.1 42.3 20.9 53.8 213.9 15.6 39.2 21.2 440.4 12.3 20.4 34.4 14.8 12.4 27.6 14.5 35.9 34.5 4.1 12.5 38.8 10.7 66.8 38.3 30.9 18.5 25.6 14.4 16.2 95.5 245.2 80.7 28.6 50.4 88.9 24.4 78.0 20.0 119.4 26.7 37.2 32.4 19.5 25.6 50.9 35.7 8.8 36.5 10.8 26.6 26.3 41.4 35.3 308.8 13.7 3.9 83.3 89.5 90.7 11.5 15.0 46.2 C1orf74 "FLJ25078, URLC4" ENSG00000162757 "Chromosome 1 open reading frame 74" Q96LT6 1 209779208-209784559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 6.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 14.9;Glandular and luminal cells: 28.4;Squamous epithelial cells: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028496 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA028496: AB_10602698" "unprognostic (3.25e-1)" "prognostic unfavorable (8.52e-6)" "unprognostic (8.41e-3)" "unprognostic (9.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-2)" "unprognostic (9.98e-2)" "unprognostic (3.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.95e-1)" "unprognostic (2.81e-1)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-2)" "unprognostic (1.07e-1)" "unprognostic (5.40e-2)" 0.6 0.9 0.7 2.4 0.7 1.1 2.2 1.8 0.7 0.9 0.2 1.6 1.3 0.8 2.0 4.0 1.1 0.9 1.5 0.7 0.9 1.9 1.7 0.9 4.3 0.8 0.8 0.9 0.8 1.2 0.8 1.1 0.8 1.6 2.0 0.9 1.9 0.9 1.0 6.7 2.8 0.6 0.7 4.2 1.7 1.3 1.1 2.1 1.2 0.9 2.4 1.9 1.7 0.8 4.7 2.4 1.5 0.8 2.0 2.3 3.5 2.6 3.4 3.1 3.2 4.9 3.5 4.9 1.5 1.7 1.9 9.3 0.9 7.6 3.6 4.9 3.1 3.2 1.7 0.4 2.8 4.6 1.4 1.4 6.6 3.9 6.3 2.6 1.8 6.6 6.5 3.5 2.7 2.4 3.9 4.7 6.4 3.2 4.1 4.0 7.2 6.9 2.7 4.0 6.0 6.5 3.5 2.7 4.0 3.4 4.2 2.4 1.7 2.6 3.1 2.7 4.2 3.2 3.4 5.4 2.3 3.7 3.8 4.7 0.8 0.7 1.3 0.9 0.9 1.8 0.6 1.0 1.6 3.7 1.1 1.2 0.5 1.5 0.5 2.7 0.6 0.9 0.7 0.7 1.8 0.7 0.7 0.9 0.8 0.8 0.8 0.7 1.1 0.8 0.6 3.2 2.2 0.0 1.1 2.2 6.1 4.6 6.8 1.6 3.7 2.8 2.0 0.0 1.8 0.0 0.0 3.9 1.5 3.5 7.9 1.9 0.1 14.9 1.8 0.8 3.6 2.1 0.5 2.0 5.0 0.9 2.6 28.4 1.3 2.2 1.4 2.3 2.8 1.7 0.6 5.9 0.0 1.3 0.3 0.6 2.5 1.6 0.0 1.0 1.3 2.2 0.0 0.0 0.3 4.1 3.5 0.0 0.6 5.1 2.4 7.4 1.8 1.3 0.0 0.4 1.0 3.6 4.7 25.0 4.8 4.0 1.1 2.8 3.4 12.1 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C1QBP "gC1Q-R, gC1qR, HABP1, p32, SF2p32" ENSG00000108561 "Complement C1q binding protein" Q07021 17 5432777-5448830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Apoptosis, Complement pathway, Host-virus interaction, Immunity, Innate immunity, mRNA processing, mRNA splicing, Ribosome biogenesis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026483 Supported Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA 410000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" Mitochondria "HPA026483: AB_1847108" "unprognostic (2.18e-1)" "unprognostic (1.74e-1)" "unprognostic (3.80e-2)" "unprognostic (6.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.76e-2)" "unprognostic (7.47e-2)" "unprognostic (4.62e-2)" "unprognostic (2.40e-3)" "unprognostic (6.03e-2)" "unprognostic (4.60e-3)" "unprognostic (3.08e-2)" "unprognostic (7.80e-3)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-1)" "unprognostic (3.97e-1)" 79.3 135.4 85.5 84.1 85.7 121.2 108.7 91.5 118.3 58.4 119.6 140.3 95.9 66.4 68.3 138.6 74.5 48.7 126.3 89.5 94.3 136.4 134.5 54.7 115.7 89.6 92.3 52.7 72.9 127.7 81.3 75.8 93.2 63.9 141.6 86.7 66.2 73.1 174.2 81.3 78.4 80.9 93.1 73.5 74.3 62.5 90.7 98.5 65.1 160.1 135.6 108.4 73.9 97.3 443.8 671.0 233.0 378.0 169.8 207.7 313.7 330.4 268.5 751.4 458.8 646.8 143.7 941.8 317.8 251.3 271.3 385.8 756.7 448.9 689.8 216.6 1300.5 433.9 312.4 762.2 269.9 535.6 331.0 231.4 404.1 414.6 593.1 181.1 390.0 548.2 526.1 234.4 296.1 308.6 766.4 385.6 525.9 497.2 396.7 601.2 329.1 515.0 440.5 328.7 186.0 348.0 271.4 344.4 483.6 232.1 218.1 267.1 231.1 240.1 219.7 275.9 729.9 122.0 201.2 415.0 229.3 506.2 376.8 68.1 197.6 49.9 217.1 212.0 283.5 330.1 239.0 215.4 389.5 289.8 289.7 245.7 15.5 240.7 166.4 325.4 203.6 432.6 85.5 85.7 91.5 118.3 89.5 94.3 89.6 92.3 93.2 93.1 90.7 97.3 101.6 28.9 30.5 10.7 153.1 243.1 229.0 283.3 165.0 70.5 157.3 209.4 84.8 102.9 107.8 82.8 27.1 323.8 115.0 105.6 313.1 248.0 75.1 106.7 149.9 108.2 79.2 183.1 10.8 205.1 457.9 101.0 94.8 85.9 62.2 131.6 75.3 128.5 202.7 60.6 11.6 190.2 154.6 85.3 129.8 89.5 119.6 101.8 156.5 10.3 170.3 105.2 93.7 11.1 16.1 199.3 128.5 98.6 197.4 255.1 78.9 444.1 65.1 79.9 85.5 101.6 189.1 79.3 237.3 284.4 255.3 179.0 105.5 354.3 364.0 253.8 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 C1QL1 "C1QRF, C1QTNF14, CRF, CTRP14" ENSG00000131094 "Complement C1q like 1" O75973 17 44959693-44968303 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 134.0" "Cell type enriched" "Detected in some" 7 "Horizontal cells: 673.0" "Cancer enriched" "Detected in all" 7 "glioma: 116.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 34.8;SH-SY5Y: 24.8;U-2 OS: 89.0;U-251 MG: 28.1;U-87 MG: 27.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (6.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (3.63e-3)" "unprognostic (3.15e-2)" "unprognostic (2.05e-2)" "unprognostic (7.65e-2)" "unprognostic (3.40e-3)" "unprognostic (2.34e-1)" "unprognostic (6.64e-3)" "unprognostic (1.49e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.31e-8)" "unprognostic (2.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.61e-2)" "unprognostic (3.04e-1)" 7.7 0.7 18.5 0.4 17.2 0.0 0.9 26.6 32.1 3.0 16.2 4.9 2.0 13.0 0.3 1.8 4.4 0.3 4.1 15.5 21.4 21.0 0.7 0.2 0.0 134.0 41.9 0.7 4.6 0.0 2.1 0.0 24.9 7.3 0.3 8.1 0.7 0.0 0.1 0.5 6.2 0.6 32.4 0.1 3.9 0.8 21.6 0.1 0.3 0.2 0.0 6.4 1.2 24.3 4.6 5.1 1.1 17.8 0.3 0.0 0.3 0.8 0.7 0.5 1.6 0.7 0.6 0.2 3.0 0.4 5.3 0.6 2.8 0.2 0.2 12.7 7.5 0.0 7.9 0.1 2.1 0.0 2.2 0.4 0.0 0.7 0.2 6.2 0.0 3.1 0.1 0.2 0.5 1.1 4.0 0.1 3.1 0.5 10.7 6.7 0.2 0.3 0.1 0.4 34.8 24.8 15.6 1.3 1.3 0.9 4.1 0.2 0.1 1.4 89.0 0.9 28.1 1.0 0.0 0.1 27.8 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.5 17.2 26.6 32.1 15.5 21.4 134.0 41.9 24.9 32.4 21.6 24.3 0.1 0.0 0.0 4.2 0.0 0.3 0.2 1.0 0.0 22.3 0.4 3.2 1.1 5.7 0.0 0.0 10.4 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.5 0.4 5.3 0.0 0.5 0.0 0.1 1.9 0.0 0.5 0.0 0.3 1.1 0.1 0.0 673.0 11.7 0.0 0.0 0.3 0.0 0.2 0.3 0.1 0.0 1.0 0.0 17.6 0.0 84.4 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.7 0.2 1.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 C1QL2 "C1QTNF10, CTRP10" ENSG00000144119 "Complement C1q like 2" Q7Z5L3 2 119156243-119158751 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 26.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 28.3;Cone photoreceptor cells: 8.4;Oligodendrocyte precursor cells: 37.2" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 2.6" "Region enhanced" "Detected in many" "hippocampal formation: 22.7" "Low region specificity" "Detected in many" HPA057934 Uncertain "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "HPA057934: AB_2683558" "unprognostic (6.95e-2)" "unprognostic (9.74e-2)" "unprognostic (4.48e-3)" "unprognostic (1.08e-1)" "unprognostic (9.91e-4)" "unprognostic (2.60e-5)" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" 0.0 0.0 17.6 0.0 9.4 0.0 0.2 3.9 17.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 26.5 16.3 0.0 0.0 0.0 0.1 7.3 7.0 0.1 0.0 0.0 0.5 0.0 6.1 0.0 0.0 2.9 0.0 0.0 0.0 0.4 0.0 0.0 4.5 0.0 0.0 0.2 20.3 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 9.4 3.9 17.0 26.5 16.3 7.3 7.0 6.1 4.5 20.3 8.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 28.3 1.3 0.8 0.5 0.0 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 37.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 C1QL3 "C1ql, C1QTNF13, CTRP13, K100" ENSG00000165985 "Complement C1q like 3" Q5VWW1 10 16513734-16521879 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 45.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.5;Excitatory neurons: 4.8;Oligodendrocyte precursor cells: 1.0;Rod photoreceptor cells: 2.9" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 20 "amygdala: 26.8;basal ganglia: 39.1;cerebral cortex: 33.6;hippocampal formation: 45.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HDLM-2: 32.3;SCLC-21H: 19.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 72.1;cerebral cortex: 57.7;hippocampal formation: 51.2" "Secreted in brain" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (7.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (8.19e-3)" "unprognostic (6.31e-2)" "unprognostic (5.12e-2)" "unprognostic (3.89e-2)" "unprognostic (2.76e-2)" "unprognostic (2.00e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "prognostic favorable (6.29e-5)" "unprognostic (3.27e-2)" "unprognostic (1.66e-1)" "unprognostic (8.59e-2)" "unprognostic (6.12e-2)" 0.8 0.8 26.8 0.4 39.1 0.1 0.3 0.2 33.6 0.2 0.0 0.3 1.8 0.2 0.0 0.2 0.2 0.1 0.8 45.5 1.2 1.2 0.3 0.4 0.7 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.5 0.0 7.4 0.6 0.0 1.1 0.9 0.7 0.0 0.0 0.5 0.5 0.0 1.2 0.0 1.0 0.1 0.0 0.3 0.2 1.8 0.1 1.8 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 2.1 1.1 3.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 32.3 0.3 1.9 1.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.2 0.2 0.1 1.2 1.2 0.1 1.2 0.3 1.9 0.1 0.7 19.3 1.7 1.8 0.2 1.1 0.3 0.1 0.3 0.0 0.0 0.1 0.9 0.0 0.7 1.1 0.9 0.1 1.8 0.8 0.0 0.2 0.1 0.4 0.4 0.2 0.2 0.3 0.3 0.1 0.2 0.3 0.5 0.0 0.1 0.3 0.2 0.4 0.1 26.8 39.1 0.2 33.6 45.5 1.2 0.0 0.0 0.0 0.0 1.2 1.8 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.8 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C1QL4 "C1QTNF11, CTRP11" ENSG00000186897 "Complement C1q like 4" Q86Z23 12 49332409-49337188 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 7.8;testis: 4.2" "Group enriched" "Detected in some" 8 "Early spermatids: 37.2;Horizontal cells: 25.2;Late spermatids: 84.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 35.3;HAP1: 5.5;PC-3: 5.9;U-2 OS: 9.0" "Region enhanced" "Detected in some" "midbrain: 6.2" "Region enhanced" "Detected in some" "pons: 7.6" "Secreted in brain" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.97e-2)" "unprognostic (2.77e-2)" "unprognostic (4.87e-2)" "unprognostic (7.37e-2)" "unprognostic (4.48e-1)" "unprognostic (1.86e-2)" "unprognostic (2.49e-3)" "unprognostic (8.64e-3)" "unprognostic (2.89e-1)" "unprognostic (5.11e-3)" "unprognostic (7.62e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (9.73e-2)" "unprognostic (2.85e-2)" "unprognostic (9.40e-2)" "unprognostic (3.72e-2)" 0.2 0.0 0.5 0.0 1.5 0.0 0.2 0.3 0.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.9 0.0 0.0 0.0 0.8 7.8 0.0 0.0 0.1 0.2 0.0 3.9 0.1 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 4.2 0.5 0.0 0.9 0.0 0.0 0.0 1.1 0.8 0.4 1.4 0.4 35.3 0.0 0.0 0.1 0.0 0.1 0.5 1.9 0.9 0.1 0.4 2.0 0.0 2.0 0.1 5.5 0.0 0.6 0.1 2.5 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.1 0.4 0.0 1.2 0.2 0.0 0.0 0.9 0.0 0.0 0.7 0.1 5.9 0.2 0.2 0.0 0.1 0.0 0.0 3.0 0.0 0.3 1.6 0.1 0.7 0.2 0.0 0.5 9.0 0.1 0.5 0.3 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.3 0.5 0.2 1.5 0.8 7.8 3.9 0.1 0.5 0.8 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.4 1.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 25.2 0.0 0.0 0.0 0.0 0.3 84.5 0.9 0.0 3.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.3 5.6 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 C1QTNF1 "CTRP1, FLJ90694, GIP, ZSIG37" ENSG00000173918 "C1q and TNF related 1" Q9BXJ1 17 79022814-79049788 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 214.2;heart muscle: 319.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 120.0;Sertoli cells: 105.2;Smooth muscle cells: 105.8;Syncytiotrophoblasts: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 313.5;BJ hTERT+: 72.9;HHSteC: 112.3;HSkMC: 61.3;U-87 MG: 66.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025429, HPA051101" Uncertain Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 314000000 40000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "CAB025429: , HPA051101: AB_2681343" "unprognostic (2.58e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (1.20e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" "unprognostic (7.11e-2)" "unprognostic (3.18e-1)" "unprognostic (1.07e-2)" "unprognostic (1.23e-2)" "unprognostic (7.48e-2)" "unprognostic (9.81e-3)" "unprognostic (5.83e-2)" "prognostic unfavorable (9.09e-9)" "unprognostic (1.93e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-2)" "unprognostic (1.95e-2)" 214.2 75.3 9.5 14.8 15.2 0.5 156.0 16.1 13.3 50.2 45.3 38.3 4.6 45.1 6.5 18.9 63.5 24.3 319.1 9.1 18.2 25.3 45.7 44.4 14.0 18.3 25.4 70.5 14.9 13.5 17.5 42.2 18.0 57.1 6.3 0.9 34.9 44.0 27.0 38.6 29.3 13.3 14.1 35.7 25.0 5.4 21.9 5.1 115.0 21.3 6.6 34.7 42.3 13.2 0.1 32.3 0.3 0.1 313.5 27.1 0.2 13.6 72.9 7.0 11.9 2.7 14.0 0.1 1.5 5.1 18.1 0.7 1.0 0.5 5.0 0.1 3.5 0.2 11.7 1.5 112.3 0.1 0.2 61.3 0.2 14.5 0.8 9.3 8.8 1.6 0.1 0.3 1.6 0.1 0.3 0.2 3.0 3.7 27.9 0.1 22.3 0.4 0.0 0.4 1.3 5.3 9.2 1.8 32.7 1.2 0.0 0.0 1.4 32.6 0.8 4.0 4.8 0.3 0.1 0.1 66.2 0.2 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.5 15.2 16.1 13.3 9.1 18.2 18.3 25.4 18.0 14.1 21.9 13.2 36.1 0.0 0.6 4.9 0.4 6.5 0.7 12.3 0.6 0.1 9.2 1.8 10.8 5.7 0.5 1.8 0.0 21.5 0.4 3.2 0.0 19.5 0.1 0.6 17.9 38.3 4.8 2.7 0.2 5.9 1.5 23.6 2.6 0.6 0.0 25.3 120.0 1.9 2.6 0.0 0.9 6.3 2.0 7.5 11.3 0.7 10.5 1.1 3.6 5.6 10.9 0.5 0.0 0.5 0.3 3.7 3.1 3.4 0.1 1.8 0.9 0.2 0.3 0.5 105.2 12.7 105.8 0.0 0.7 0.4 4.5 47.3 0.8 18.1 5.2 0.6 C1QTNF12 "ADIPOLIN, C1QDC2, CTRP12, FAM132A, MGC105127" ENSG00000184163 "C1q and TNF related 12" Q5T7M4 1 1242446-1246722 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.8;skin 1: 6.6" "Cell type enhanced" "Detected in some" "Adipocytes: 19.5;Extravillous trophoblasts: 11.2;Proximal tubular cells: 45.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 4.1;U-2 OS: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024107 Uncertain Approved Vesicles "Secreted to blood" NA NA 38200000 "Cluster 40: NK-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA024107: AB_2101207" "unprognostic (1.10e-2)" "unprognostic (5.68e-3)" "unprognostic (3.45e-1)" "unprognostic (1.24e-2)" "unprognostic (6.60e-3)" "unprognostic (2.43e-1)" "unprognostic (2.67e-3)" "unprognostic (1.01e-2)" "unprognostic (2.58e-1)" "unprognostic (1.05e-2)" "unprognostic (8.02e-3)" "unprognostic (1.10e-2)" "unprognostic (9.68e-3)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.09e-1)" "unprognostic (1.20e-1)" 1.3 0.1 0.4 0.2 0.4 0.0 0.7 0.3 0.5 0.5 0.0 3.4 6.8 0.3 0.0 1.3 0.5 0.1 0.8 0.4 0.7 3.4 0.5 0.4 0.0 0.8 0.4 0.2 0.2 0.0 0.3 0.2 0.5 0.3 0.7 0.0 0.3 0.0 0.4 6.6 6.7 0.0 0.4 0.2 0.4 2.4 0.9 0.0 0.4 0.0 0.1 0.3 0.6 0.5 0.1 0.0 0.0 0.3 0.2 0.0 0.8 0.6 0.0 0.0 0.0 0.3 0.2 0.0 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.1 0.1 0.4 0.3 0.1 0.1 0.0 0.7 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 4.0 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.5 0.4 0.7 0.8 0.4 0.5 0.4 0.9 0.5 19.5 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 3.9 0.5 0.0 0.6 1.2 0.7 0.0 0.0 0.0 0.8 11.2 0.5 0.0 0.7 2.5 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 45.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.0 0.0 C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 23.7;Leydig cells: 23.3;Peritubular cells: 29.7;Skeletal myocytes: 16.9;Smooth muscle cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "RH-30: 34.4;U-138 MG: 15.1;U-2 OS: 8.3;WM-115: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" 2.8 0.6 0.9 0.7 0.9 0.1 1.9 1.2 1.3 4.7 0.1 2.5 1.2 3.3 1.1 1.4 2.3 1.8 3.9 0.9 0.8 0.6 0.4 2.4 0.3 0.3 1.3 1.3 0.3 0.2 0.5 0.8 0.2 1.9 1.1 0.2 1.3 1.0 1.9 1.4 2.3 1.8 0.2 0.6 2.0 1.8 2.5 0.1 2.1 2.1 0.3 2.1 2.6 0.8 0.3 0.0 0.5 0.1 0.0 0.0 0.0 3.9 5.3 0.9 3.3 0.1 0.9 0.0 0.1 1.4 0.6 0.2 0.1 0.4 0.2 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 34.4 0.0 0.0 0.2 0.0 0.8 1.0 0.1 0.2 0.1 0.4 0.1 0.2 15.1 8.3 1.5 4.4 0.1 0.0 0.0 0.5 0.0 6.8 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.9 0.9 1.2 1.3 0.9 0.8 0.3 1.3 0.2 0.2 2.5 0.8 2.0 0.0 0.0 0.0 0.0 6.5 0.2 0.2 0.6 0.8 0.3 0.4 1.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.1 0.0 0.1 1.0 4.2 0.0 0.0 0.6 0.2 0.3 23.7 0.5 0.2 0.0 0.2 1.1 0.0 1.1 0.0 6.2 0.1 0.0 0.0 6.2 0.4 23.3 0.5 5.4 1.0 0.6 0.1 0.0 1.0 0.3 0.1 0.1 29.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 16.9 22.8 0.1 0.5 0.6 3.8 0.8 0.3 2.1 0.1 0.3 C1QTNF3 "2310005P21Rik, Corcs, Cors, Cors-26, CTRP3" ENSG00000082196 "C1q and TNF related 3" Q9BXJ4 5 34017858-34043213 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.4;salivary gland: 52.0" "Cell type enhanced" "Detected in many" "Early spermatids: 161.6;Fibroblasts: 61.5;Late spermatids: 387.6;Muller glia cells: 227.2;Skeletal myocytes: 77.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 211 "U-266/84: 810.2" "HPA064996, HPA066011" Uncertain Approved "Golgi apparatus" "Secreted to blood" NA NA 44100000 24000000 "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA064996: AB_2685399, HPA066011: AB_2685597" "unprognostic (7.71e-2)" "unprognostic (2.81e-3)" "unprognostic (5.83e-2)" "unprognostic (6.58e-2)" "unprognostic (3.14e-2)" "unprognostic (1.98e-1)" "unprognostic (2.21e-1)" "unprognostic (2.09e-3)" "unprognostic (5.18e-2)" "unprognostic (1.68e-2)" "unprognostic (1.35e-2)" "unprognostic (2.70e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (4.89e-3)" "unprognostic (1.80e-1)" "unprognostic (9.38e-3)" "unprognostic (2.35e-1)" 7.3 0.5 4.1 1.7 5.0 0.6 6.8 6.8 4.0 3.6 2.6 11.2 3.5 2.7 1.0 33.4 3.0 5.9 0.9 3.9 7.0 4.8 1.1 4.1 0.8 5.3 4.3 1.4 1.7 0.3 1.3 0.6 4.5 2.2 10.0 23.7 52.0 4.9 2.2 2.3 8.9 23.3 5.8 0.7 10.7 11.4 4.2 1.0 1.6 9.9 0.4 13.2 3.6 5.1 0.7 0.1 0.2 0.3 0.0 0.1 0.3 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.9 0.2 0.0 0.1 0.0 0.0 0.2 0.9 0.0 0.2 0.7 0.8 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.8 3.2 0.0 0.0 0.0 1.1 0.1 0.0 0.1 0.2 0.2 1.6 0.0 0.1 0.6 0.1 0.0 3.8 0.6 0.1 1.0 0.0 1.0 0.9 810.2 1.3 0.0 0.8 3.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 4.1 5.0 6.8 4.0 3.9 7.0 5.3 4.3 4.5 5.8 4.2 5.1 2.3 3.2 2.0 0.0 2.0 5.7 0.6 0.4 1.8 5.1 3.0 2.3 1.0 8.6 0.8 3.7 0.0 0.9 1.5 0.7 1.9 1.2 161.6 2.6 1.0 7.2 1.8 1.3 0.0 1.4 0.5 61.5 1.5 2.6 0.0 1.8 0.4 1.3 1.3 8.4 0.0 1.4 2.0 0.6 9.6 387.6 1.8 1.1 7.2 0.0 0.3 227.2 1.0 0.0 0.0 0.5 1.5 2.6 0.2 0.8 0.8 2.1 1.2 11.9 0.0 77.5 4.5 6.2 2.0 1.1 5.8 0.4 1.3 1.0 2.0 0.5 C1QTNF5 "CTRP5, DKFZp586B0621, LORD" ENSG00000223953 "C1q and TNF related 5" Q9BXJ0 11 119338942-119340940 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Ductal cells: 4.7;Endothelial cells: 1.5;Exocrine glandular cells: 1.1;Fibroblasts: 3.6;Gastric mucus-secreting cells: 1.5;Smooth muscle cells: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 17.7;fHDF/TERT166: 14.7;HHSteC: 35.8;hTERT-RPE1: 28.5;HUVEC TERT2: 54.7;TIME: 50.5" "Low region specificity" "Detected in all" "CAB025607, HPA038604" Uncertain "Secreted to blood" NA NA 219000000 1500000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "CAB025607: , HPA038604: AB_2676110" 51.9 13.4 19.1 12.9 20.8 0.1 36.6 20.3 20.7 38.4 25.5 23.0 14.9 50.7 7.5 11.5 27.2 45.5 36.1 17.3 19.8 42.4 11.1 42.0 8.9 21.8 22.2 11.3 18.8 6.8 14.8 13.6 20.4 19.5 7.8 2.2 16.9 8.7 8.8 20.4 24.2 26.8 21.7 32.3 27.1 2.6 27.5 2.8 32.0 15.2 4.6 31.6 20.8 21.7 0.0 0.0 3.3 0.0 17.7 4.9 0.2 4.6 0.3 0.6 2.7 0.1 0.0 0.1 2.0 14.7 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 35.8 0.0 0.0 8.4 0.0 0.3 0.0 28.5 54.7 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.9 0.0 0.1 0.0 4.1 0.0 0.1 0.0 0.0 6.5 0.0 0.0 1.1 0.9 0.0 0.0 50.5 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 20.8 20.3 20.7 17.3 19.8 21.8 22.2 20.4 21.7 27.5 21.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 1.5 0.0 0.0 0.0 1.1 0.0 3.6 1.5 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 C1QTNF6 "CTRP6, ZACRP6" ENSG00000133466 "C1q and TNF related 6" Q9BXI9 22 37180166-37199385 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.7;placenta: 29.6" "Cell type enriched" "Detected in many" 11 "Extravillous trophoblasts: 398.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 114.2;RT4: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002042 Enhanced Approved Nucleoplasm "Secreted to blood" No No 354000000 "Cluster 48: NK-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA002042: AB_1078342" "unprognostic (9.65e-2)" "unprognostic (1.21e-2)" "unprognostic (2.32e-1)" "unprognostic (2.23e-3)" "unprognostic (1.25e-3)" "unprognostic (3.01e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.60e-6)" "unprognostic (6.96e-2)" "unprognostic (5.11e-2)" "unprognostic (2.61e-2)" "unprognostic (1.72e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.61e-2)" "unprognostic (5.36e-2)" "unprognostic (1.08e-3)" "unprognostic (1.52e-2)" 4.9 6.7 4.4 6.6 4.5 1.6 4.0 4.3 5.3 11.1 4.3 5.5 1.6 31.7 1.4 2.7 7.0 8.8 3.7 4.5 4.3 7.4 13.0 5.2 5.1 5.1 4.5 5.5 3.5 2.2 2.5 29.6 4.8 6.8 3.6 0.5 3.2 2.9 1.5 5.0 5.4 8.2 4.4 6.5 3.5 6.2 4.8 2.4 3.8 0.7 2.3 5.6 4.3 6.3 17.7 20.5 10.7 3.6 1.8 21.3 32.6 3.4 6.8 2.8 2.0 3.8 24.7 0.1 14.1 6.0 1.5 34.9 0.4 8.4 1.2 4.9 2.6 2.8 8.3 3.8 7.1 0.1 2.3 29.2 4.9 2.3 0.6 7.3 25.5 0.8 0.1 7.7 1.1 114.2 0.0 0.5 7.1 2.5 0.3 0.2 0.1 2.8 24.5 50.7 1.8 14.6 1.0 19.7 2.8 5.5 7.0 0.5 9.4 1.1 5.6 0.4 0.1 15.5 0.4 0.1 2.1 2.0 3.2 0.4 0.1 0.5 0.2 0.2 0.2 0.2 0.4 0.3 0.1 0.7 0.9 0.7 0.5 1.5 0.1 0.3 1.4 0.3 4.4 4.5 4.3 5.3 4.5 4.3 5.1 4.5 4.8 4.4 4.8 6.3 3.2 0.0 0.0 13.7 2.9 1.5 2.1 1.9 0.6 1.0 8.6 4.2 1.8 1.5 2.2 1.8 0.0 8.1 1.5 7.9 1.9 3.4 2.0 4.8 30.8 6.8 0.0 0.8 3.3 1.1 398.9 7.6 2.0 9.6 1.3 19.8 10.0 7.2 9.3 0.0 4.3 3.1 0.0 1.9 1.4 8.9 0.6 1.2 5.4 3.7 1.1 4.5 1.0 4.0 7.8 2.7 2.8 0.4 3.4 0.8 2.0 1.6 2.7 0.9 0.0 2.2 7.5 7.2 4.5 1.0 0.3 34.5 3.1 7.6 4.4 1.5 C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.8;Fibroblasts: 32.3;Leydig cells: 22.7;Peritubular cells: 31.6;Skeletal myocytes: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 4.2;ASC TERT1: 2.8;HSkMC: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" NA NA 238000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" 7.8 1.4 1.2 1.6 1.2 0.0 4.7 1.2 2.6 23.1 0.0 8.6 1.2 16.5 10.2 6.0 6.3 14.0 7.0 0.8 1.8 5.5 1.2 10.8 1.2 1.1 1.8 20.9 0.8 0.1 1.1 7.2 0.9 9.5 4.2 0.1 2.5 3.2 0.6 3.2 3.8 12.0 0.6 9.7 9.0 1.7 1.8 0.4 3.8 6.6 0.5 10.3 10.3 1.3 0.0 0.0 0.0 0.0 4.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.6 0.8 1.8 1.1 1.8 0.9 0.6 1.8 1.3 1.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 15.8 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.1 0.2 6.5 0.5 0.0 0.0 1.0 0.0 0.3 32.3 0.0 0.6 0.0 2.0 0.0 0.0 0.1 1.7 4.4 0.0 0.0 0.0 3.2 0.5 22.7 0.3 5.4 6.5 0.0 0.3 0.0 2.5 0.7 0.0 0.0 31.6 0.2 0.1 0.0 2.8 0.0 1.2 6.6 15.2 9.9 0.0 0.1 0.6 3.0 0.0 0.7 5.7 0.0 0.1 C1QTNF8 "CTRP8, UNQ5829" ENSG00000184471 "C1q and TNF related 8" P60827 16 1088226-1096244 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.8;fallopian tube: 1.8;pituitary gland: 2.0" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Endometrial ciliated cells: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056438 Uncertain "Secreted - unknown location" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 49: Ciliated cells - Cilium organization" "HPA056438: AB_2683134" "unprognostic (8.65e-2)" "unprognostic (2.56e-2)" "unprognostic (5.46e-2)" 0.0 0.3 0.4 0.0 0.4 0.0 0.0 0.5 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.9 0.0 0.0 0.1 0.0 1.9 2.8 0.0 0.0 0.0 2.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.4 0.5 0.9 1.9 2.8 1.2 2.1 0.8 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C1QTNF9 "AQL1, C1QTNF9A, CTRP9, MGC48915" ENSG00000240654 "C1q and TNF related 9" P0C862 13 24307166-24322535 "Predicted secreted proteins, Transporters" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 8.4" "Group enriched" "Detected in some" 10 "Adipocytes: 34.9;Endothelial cells: 12.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056632 Uncertain "Secreted to blood" NA NA 210000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA056632: AB_2683197" "unprognostic (1.18e-2)" "unprognostic (3.22e-2)" "unprognostic (2.44e-2)" "unprognostic (3.14e-3)" "unprognostic (9.22e-2)" "unprognostic (1.48e-1)" "unprognostic (1.96e-2)" "unprognostic (3.63e-2)" "unprognostic (1.03e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-2)" "unprognostic (4.16e-2)" "unprognostic (3.29e-4)" "unprognostic (1.38e-2)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (2.22e-1)" 3.1 0.2 0.3 0.1 0.2 0.2 1.5 0.4 0.3 0.3 0.0 1.6 0.6 0.3 0.4 0.4 0.3 0.8 3.8 1.9 0.5 0.3 0.5 0.2 0.2 0.1 0.1 0.1 0.6 0.1 0.1 1.3 0.2 0.6 0.3 0.4 0.4 0.1 8.4 2.1 0.6 0.6 0.0 0.3 0.5 0.9 0.2 0.2 0.2 3.3 0.1 0.8 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.1 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.4 0.3 1.9 0.5 0.1 0.1 0.2 0.0 0.2 0.2 34.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.3 2.2 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.1 2.0 0.5 0.1 12.9 0.0 0.0 0.2 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.4 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.7 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.9 0.9 0.0 0.0 0.0 0.0 2.2 0.0 0.1 C1QTNF9B CTRP9B ENSG00000205863 "C1q and TNF related 9B" B2RNN3 13 23891099-23897502 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.8;skin 1: 17.9;testis: 8.8" "Cell type enhanced" "Detected in some" "Adipocytes: 4.3;Early spermatids: 2.3;Endothelial cells: 1.4;Late spermatids: 2.1" "Cancer enhanced" "Detected in single" "prostate cancer: 0.8" "Region enriched" "Detected in many" 4 "hippocampal formation: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 4.8;OE19: 3.6" HPA056632 Uncertain "Secreted - unknown location" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA056632: AB_2683197" "unprognostic (3.43e-1)" "unprognostic (3.42e-1)" "unprognostic (2.18e-2)" "unprognostic (9.51e-2)" "unprognostic (2.18e-1)" "unprognostic (4.10e-2)" "unprognostic (2.43e-1)" "unprognostic (3.32e-3)" "unprognostic (1.52e-2)" "unprognostic (7.26e-2)" "unprognostic (3.01e-3)" "unprognostic (7.04e-2)" "unprognostic (5.56e-3)" "unprognostic (3.89e-1)" "unprognostic (1.82e-1)" "unprognostic (1.35e-1)" "unprognostic (1.34e-1)" 1.2 0.7 1.0 0.6 0.9 0.2 0.4 0.3 1.2 0.3 0.4 0.4 0.5 0.7 0.0 1.6 0.3 0.8 3.5 7.8 1.9 0.2 0.1 0.4 0.2 0.3 0.6 0.4 0.6 0.1 1.1 0.6 0.3 4.2 0.1 0.7 1.6 0.2 4.0 17.9 0.2 0.7 0.3 1.3 0.8 8.8 0.7 0.0 0.5 2.0 0.0 0.6 0.1 0.4 0.7 1.7 0.6 0.7 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.7 1.0 0.1 0.0 0.0 1.3 1.7 0.0 0.0 0.0 1.0 1.4 0.3 0.9 0.9 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.8 0.0 4.8 0.4 0.9 0.0 1.1 0.2 0.0 1.1 3.6 1.6 0.6 0.8 1.3 0.0 0.0 2.0 0.0 1.0 0.0 1.7 0.4 0.5 0.2 0.1 1.6 0.4 0.0 1.0 1.4 0.2 0.7 1.9 0.6 0.3 0.0 0.2 0.4 0.3 0.3 0.1 0.2 0.0 0.0 0.1 0.5 0.1 0.1 0.0 0.4 0.4 0.7 0.0 0.1 1.0 0.9 0.3 1.2 7.8 1.9 0.3 0.6 0.3 0.3 0.7 0.4 4.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.3 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.9 0.0 0.3 0.0 0.0 0.4 0.0 0.0 C1R ENSG00000159403 "Complement C1r" 12 7080214-7092540 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "liver: 1425.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 442.3;Fibroblasts: 684.4;Hepatocytes: 1444.2;Leydig cells: 1142.6;Peritubular cells: 388.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1089.8;ASC TERT1: 546.0;BJ hTERT+: 461.9;BJ hTERT+ SV40 Large T+ RasG12V: 303.4;HSkMC: 672.1" "Low region specificity" "Detected in many" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001251: AB_2666252, HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" 540.6 203.6 15.8 122.4 15.9 1.1 400.6 15.9 23.3 470.5 21.7 277.3 38.3 353.8 80.8 119.0 526.3 279.1 458.7 15.4 19.6 148.9 1425.6 340.3 72.4 23.4 19.9 644.3 88.0 11.0 63.9 52.4 18.4 205.2 100.9 5.8 158.3 87.0 69.4 177.7 228.1 157.7 18.1 192.1 242.7 46.7 18.1 34.7 223.4 74.2 75.3 468.4 394.3 18.0 1.2 8.9 0.9 9.1 1089.8 546.0 0.4 108.9 461.9 143.0 303.4 1.4 2.4 0.5 4.5 108.8 11.8 2.3 11.8 5.5 18.3 18.3 1.1 0.5 4.1 3.6 226.5 0.8 2.3 672.1 3.2 74.7 4.7 121.0 2.9 0.5 0.3 20.5 21.2 0.1 8.0 0.8 3.1 0.1 0.9 8.6 3.8 0.8 0.9 5.5 0.4 2.3 95.1 3.7 2.8 1.3 0.2 0.2 0.4 38.3 6.3 152.1 0.8 1.1 3.0 0.2 53.1 1.0 5.4 0.0 0.0 0.6 0.3 0.0 0.5 0.0 0.2 0.7 0.0 0.0 0.6 0.6 0.5 0.8 0.0 0.0 0.3 0.1 15.8 15.9 15.9 23.3 15.4 19.6 23.4 19.9 18.4 18.1 18.1 18.0 45.4 22.4 90.5 3.6 7.1 54.7 58.8 76.6 33.6 0.3 5.9 30.9 20.8 183.0 22.9 18.4 2.1 4.1 1.8 0.7 3.9 280.8 4.6 13.3 442.3 45.4 0.0 40.6 0.9 44.5 3.7 684.4 16.3 11.6 10.1 24.9 114.9 1444.2 11.2 0.0 0.3 0.7 0.0 40.9 66.9 29.2 1142.6 7.0 53.4 13.1 1.6 16.0 0.0 2.5 0.1 51.1 1.3 388.1 6.2 17.7 0.3 6.1 5.3 1.4 170.9 87.5 140.4 6.8 6.7 5.6 40.1 5.2 11.5 15.2 0.7 11.2 C1RL "C1r-LP, C1RL1" ENSG00000139178 "Complement C1r subcomponent like" Q9NZP8 12 7089587-7109238 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 141.9" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 54.2;Hepatocytes: 140.0;Leydig cells: 55.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 38.2;HSkMC: 43.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011338, CAB026172" Supported "Secreted to blood" NA NA 5500000000 15000000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "CAB026172: , HPA011338: AB_1847111" "prognostic favorable (7.92e-4)" "unprognostic (7.76e-2)" "unprognostic (3.91e-3)" "unprognostic (5.25e-3)" "unprognostic (2.92e-3)" "unprognostic (9.60e-2)" "unprognostic (2.75e-3)" "unprognostic (7.76e-2)" "unprognostic (1.22e-1)" "unprognostic (4.34e-1)" "unprognostic (9.58e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.75e-1)" "unprognostic (5.74e-2)" "unprognostic (2.52e-1)" "unprognostic (2.26e-3)" 38.3 72.5 3.4 12.2 3.3 8.2 36.5 2.6 3.1 38.6 7.1 28.8 7.6 30.2 6.3 17.5 40.8 11.7 18.4 2.7 4.0 20.1 141.9 33.1 9.5 7.4 5.0 49.4 36.7 8.0 17.5 5.1 4.4 29.3 8.7 1.5 33.7 6.9 11.0 18.1 26.3 13.7 3.7 32.3 27.5 6.1 3.9 6.9 21.7 6.0 7.7 38.1 27.5 3.3 3.0 7.7 0.7 7.9 22.4 38.2 5.4 4.9 22.7 5.0 14.8 4.9 13.4 1.3 4.1 4.1 5.0 6.4 2.1 8.1 1.9 12.0 0.4 4.8 8.5 11.4 18.7 1.0 21.9 43.1 15.7 3.0 9.3 23.3 5.3 2.8 3.6 3.1 3.1 0.1 0.7 0.9 1.4 0.6 0.2 2.7 0.0 1.0 13.1 13.2 0.6 1.7 16.7 2.0 2.8 1.3 1.9 4.1 5.0 4.3 7.7 4.9 0.9 2.3 1.0 0.2 8.1 3.4 2.0 3.8 0.7 4.0 0.6 1.1 0.3 1.2 0.6 0.5 0.8 0.5 0.4 0.4 5.4 0.3 1.3 0.4 0.4 0.4 3.4 3.3 2.6 3.1 2.7 4.0 7.4 5.0 4.4 3.7 3.9 3.3 11.0 16.0 38.6 7.5 8.4 3.8 15.4 16.4 25.6 0.5 15.6 14.5 2.6 30.0 24.6 5.5 2.1 0.2 7.3 8.3 1.9 36.3 0.1 7.9 22.6 14.6 4.2 7.8 10.2 54.2 0.4 29.0 27.5 10.4 3.8 13.8 25.0 140.0 3.6 0.0 1.3 7.7 10.2 10.0 4.9 3.0 55.6 10.2 3.6 14.0 13.3 4.0 21.6 2.0 0.4 25.8 9.7 20.3 8.0 10.2 9.3 8.2 15.9 1.1 0.0 11.8 10.1 0.6 0.9 8.5 3.1 0.1 9.7 13.6 9.5 8.7 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 2915.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 687.0;Hepatocytes: 2795.1;Leydig cells: 1193.2;Peritubular cells: 640.1" "Cancer enhanced" "Detected in all" "liver cancer: 276.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.2" "Cell line enhanced" "Detected in many" "ASC diff: 769.5;ASC TERT1: 1012.7;BJ hTERT+: 336.1;HSkMC: 540.2" "Not detected" "Not detected" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 93000000000 14000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favorable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 416.4 136.1 26.4 207.7 28.5 1.7 252.5 27.1 43.1 309.2 36.7 192.4 84.6 209.0 147.2 152.9 315.4 543.8 191.5 25.4 34.8 60.2 2915.2 224.9 209.2 44.3 31.7 485.9 62.1 21.8 33.1 52.9 31.2 174.4 215.2 9.7 96.9 139.1 57.0 104.1 154.2 251.8 30.9 168.5 150.1 90.0 30.9 88.1 139.0 154.7 192.5 455.7 189.8 31.3 0.2 18.6 1.2 10.2 769.5 1012.7 4.5 143.3 336.1 74.7 135.7 0.9 2.0 0.5 19.7 179.6 20.2 1.1 0.3 2.1 6.7 0.7 0.7 0.5 5.6 48.2 230.3 1.8 0.9 540.2 2.8 60.2 4.4 94.2 0.1 0.2 0.4 0.1 9.9 0.0 0.4 1.6 10.3 0.0 0.6 0.2 1.1 1.5 3.1 2.5 0.8 0.9 86.6 1.8 2.1 17.4 0.1 0.0 0.5 34.2 2.6 133.8 0.2 0.6 0.5 0.8 73.6 1.2 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 26.4 28.5 27.1 43.1 25.4 34.8 44.3 31.7 31.2 30.9 30.9 31.3 37.6 16.0 41.0 9.4 5.7 76.2 18.9 22.2 23.9 0.9 4.5 15.4 21.5 171.6 15.5 3.7 0.0 3.7 0.7 0.1 1.9 285.2 6.6 8.7 272.4 30.6 0.0 112.2 2.9 42.9 2.5 687.0 11.2 7.3 5.1 25.7 93.5 2795.1 8.1 5.0 1.7 0.0 2.0 62.8 103.7 29.9 1193.2 6.4 88.9 19.7 1.0 15.2 0.0 1.5 0.6 31.7 0.1 640.1 1.8 9.7 0.0 7.1 4.6 1.1 138.1 34.9 127.6 6.3 5.3 6.3 53.8 2.6 12.8 30.7 0.2 5.2 C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945672 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 477.9" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 142.4;Hepatocytes: 380.3;Hofbauer cells: 282.7;Kupffer cells: 99.3" "Cancer enriched" "Detected in all" 9 "liver cancer: 100.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "intermediate monocyte: 21.1;non-classical monocyte: 25.9" "Lineage enriched" "Detected in single" 35 "monocytes: 25.9" "Cell line enriched" "Detected in some" 5 "Karpas-707: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB016775 Supported "Secreted to blood" NA NA 34000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB016775: " "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (1.49e-3)" "unprognostic (7.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.36e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-1)" "unprognostic (2.59e-3)" "unprognostic (3.27e-2)" "unprognostic (3.15e-3)" "prognostic unfavorable (2.64e-7)" "unprognostic (2.05e-1)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.55e-2)" 42.6 12.1 0.8 27.6 1.0 3.2 11.7 0.9 1.4 8.1 1.7 14.3 16.7 7.0 1.3 7.6 12.0 23.0 8.5 0.7 1.1 23.2 477.9 80.0 27.8 3.0 2.6 5.3 1.9 0.9 3.8 48.4 3.0 5.4 13.0 0.4 9.1 0.9 2.1 5.8 30.2 23.6 2.1 46.3 12.0 4.1 3.7 5.5 3.3 2.7 12.5 23.6 5.3 2.1 0.3 0.1 0.1 0.6 0.1 0.0 6.8 0.5 0.3 0.4 0.3 0.4 0.3 0.6 3.5 1.0 0.6 0.5 0.1 0.0 0.3 0.2 0.4 0.3 0.4 52.8 1.1 0.1 0.7 2.7 0.3 0.6 0.1 0.6 0.0 0.7 0.5 284.0 0.0 0.0 0.4 0.5 0.3 0.1 0.0 0.2 16.5 3.0 0.0 0.1 0.3 0.3 2.6 0.3 0.2 0.3 0.2 9.5 0.2 0.2 0.7 0.5 0.1 0.9 31.6 2.7 0.8 0.9 0.1 0.1 5.6 0.0 0.1 21.1 0.1 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.5 0.1 25.9 0.0 0.0 2.2 0.8 1.0 0.9 1.4 0.7 1.1 3.0 2.6 3.0 2.1 3.7 2.1 2.1 25.6 142.4 2.6 1.9 3.3 1.1 2.0 0.6 1.4 1.3 1.3 0.6 25.8 11.2 1.8 0.0 2.1 0.1 1.8 0.0 0.6 0.3 1.5 18.7 1.9 2.4 10.7 6.6 2.7 2.7 19.8 3.1 1.3 3.8 0.2 21.0 380.3 282.7 1.7 6.3 11.3 0.0 99.3 5.0 1.3 6.8 32.6 3.6 7.5 7.3 0.1 0.0 1.0 1.7 4.5 33.1 1.2 0.4 4.0 55.2 35.7 9.4 0.9 0.0 5.6 3.5 0.8 1.4 0.7 2.8 4.0 2.0 0.5 15.8 4.5 C20orf203 FLJ33706 ENSG00000198547 "Chromosome 20 open reading frame 203" Q8NBC4 20 32631625-32673941 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.1;Excitatory neurons: 4.8;Horizontal cells: 15.2;Inhibitory neurons: 5.0;Oligodendrocyte precursor cells: 2.5;Rod photoreceptor cells: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "basophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cell line enhanced" "Detected in some" "HEL: 3.3;HMC-1: 3.3;U-2 OS: 2.0" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (6.24e-2)" "unprognostic (3.39e-3)" "unprognostic (8.39e-3)" "unprognostic (2.06e-1)" "unprognostic (1.19e-2)" "unprognostic (6.70e-3)" "unprognostic (7.53e-2)" "unprognostic (2.52e-1)" "unprognostic (5.39e-2)" "unprognostic (6.22e-2)" "unprognostic (1.00e-2)" "unprognostic (1.39e-3)" "unprognostic (1.25e-10)" "unprognostic (3.37e-1)" "unprognostic (2.04e-1)" "unprognostic (1.23e-1)" "unprognostic (7.46e-5)" 0.1 0.2 0.4 0.1 0.8 0.1 0.5 0.5 1.3 0.3 0.0 0.1 0.0 0.6 0.9 0.2 0.5 0.2 0.2 0.3 0.2 0.1 0.3 0.1 0.3 0.4 0.2 0.8 0.1 0.2 0.2 0.5 0.3 0.3 1.4 0.1 0.5 0.0 0.6 0.1 0.3 0.0 0.3 0.1 0.3 0.5 0.5 0.5 0.3 0.5 0.1 1.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.2 0.1 0.0 0.2 3.3 0.0 0.0 0.3 0.0 3.3 0.4 0.2 0.3 0.1 0.2 0.2 0.2 0.2 0.2 0.9 0.0 0.3 0.8 0.2 0.0 0.0 0.3 0.1 0.3 0.5 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 2.0 0.0 0.0 0.8 0.2 0.2 0.0 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.5 1.3 0.3 0.2 0.4 0.2 0.5 0.0 0.5 1.0 0.1 0.0 0.0 1.6 0.0 0.3 0.1 0.0 0.0 4.1 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.1 15.2 5.0 0.0 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 1.5 0.0 2.5 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 C20orf204 "DKFZp434G015, FLJ27267, LINC00176, NCRNA00176, PRR17" ENSG00000196421 "Chromosome 20 open reading frame 204" A0A1B0GTL2 20 64034344-64039962 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0" "Cell type enhanced" "Detected in some" "Adipocytes: 4.5;Breast glandular cells: 1.3;Endometrial stromal cells: 2.0;Endothelial cells: 4.3;Glandular and luminal cells: 1.8;T-cells: 1.1" "Cancer enriched" "Detected in some" 6 "ovarian cancer: 7.2" "Region enriched" "Detected in single" 7 "cerebellum: 4.0" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 2.6;naive CD4 T-cell: 5.8;naive CD8 T-cell: 4.7;T-reg: 1.4" "Lineage enriched" "Detected in single" 9 "T-cells: 5.8" "Cell line enriched" "Detected in some" 7 "Hep G2: 49.0" "Low region specificity" "Detected in single" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.84e-1)" "unprognostic (4.02e-2)" "unprognostic (2.36e-2)" "unprognostic (2.49e-1)" "unprognostic (9.66e-2)" "unprognostic (3.49e-2)" "unprognostic (3.00e-1)" "unprognostic (1.11e-1)" "unprognostic (3.50e-1)" "unprognostic (9.20e-3)" "unprognostic (4.43e-3)" "unprognostic (4.34e-2)" "unprognostic (2.49e-6)" "unprognostic (5.83e-2)" "unprognostic (4.58e-2)" "unprognostic (1.88e-2)" "unprognostic (2.79e-4)" 0.3 0.1 0.3 0.1 0.3 0.0 0.3 4.0 0.4 0.5 0.0 0.2 0.0 0.3 0.0 0.4 0.8 0.0 0.3 0.2 0.3 0.5 0.2 0.2 0.0 0.2 0.4 0.4 0.3 0.1 0.9 0.0 0.5 0.5 0.0 0.0 0.1 0.0 0.2 0.2 0.7 0.0 0.2 0.3 0.1 0.6 0.2 1.0 0.3 0.0 0.0 0.1 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.2 0.0 0.0 49.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.0 1.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.8 0.0 0.0 5.8 4.7 0.2 0.6 0.0 0.0 1.4 0.4 0.3 0.3 4.0 0.4 0.2 0.3 0.2 0.4 0.5 0.2 0.2 0.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.0 0.8 2.0 4.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 C20orf27 FLJ20550 ENSG00000101220 "Chromosome 20 open reading frame 27" Q9GZN8 20 3753508-3767781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 178.7;Hofbauer cells: 142.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 144.6;intermediate monocyte: 249.1;myeloid DC: 199.4;non-classical monocyte: 235.3" "Group enriched" "Detected in all" 5 "dendritic cells: 199.4;monocytes: 249.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047483 Approved Approved Nucleoplasm,Cytosol NA NA 140000 "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA047483: AB_2680064" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.21e-3)" "unprognostic (2.99e-1)" "unprognostic (2.48e-1)" "prognostic unfavorable (1.69e-5)" "unprognostic (8.36e-2)" "unprognostic (2.07e-1)" "unprognostic (4.53e-2)" "unprognostic (3.54e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (1.80e-1)" "unprognostic (2.16e-1)" "unprognostic (1.49e-1)" "unprognostic (1.27e-1)" 55.8 24.0 48.8 20.4 125.4 103.6 45.2 44.7 70.9 39.5 33.7 117.3 17.0 42.5 8.7 29.6 51.8 25.5 27.9 45.6 63.3 25.7 24.7 20.8 24.5 52.9 59.3 66.3 23.6 9.4 23.3 8.9 67.5 24.2 7.8 4.9 15.7 10.9 22.4 26.9 33.9 14.1 43.8 45.5 86.8 22.7 59.5 11.0 23.4 11.5 9.8 73.9 26.3 40.7 172.9 177.7 24.4 106.1 49.5 28.1 42.7 45.5 25.1 70.4 50.3 120.5 61.6 111.1 41.4 48.2 94.7 140.9 65.7 101.9 24.9 26.1 138.3 63.2 35.9 212.6 36.2 88.2 24.7 41.0 41.8 93.3 46.1 24.2 48.2 72.9 114.6 59.8 37.3 240.2 107.6 186.3 114.9 107.0 248.4 86.6 67.9 123.7 43.9 62.0 121.8 56.6 41.2 155.3 85.1 10.4 36.9 96.8 35.9 104.8 73.8 171.6 129.6 50.5 93.2 80.7 31.5 161.2 53.9 1.3 144.6 2.3 28.7 249.1 42.1 38.7 33.6 38.6 199.4 36.2 37.6 37.5 5.4 32.5 235.3 38.7 34.2 87.4 48.8 125.4 44.7 70.9 45.6 63.3 52.9 59.3 67.5 43.8 59.5 40.7 54.0 0.0 3.3 3.3 26.5 24.2 23.0 26.8 35.3 9.7 28.2 45.7 3.7 8.6 7.4 11.0 2.1 17.5 15.8 10.2 29.4 32.6 21.8 13.8 178.7 28.7 15.7 99.1 6.0 30.0 49.2 27.1 14.3 7.5 22.9 45.0 19.6 17.9 142.9 1.7 9.5 15.9 16.2 119.0 53.1 15.3 32.6 92.2 37.4 5.6 97.4 24.6 15.5 3.5 2.1 34.7 14.6 24.8 20.2 46.6 19.3 32.4 2.7 13.6 65.7 17.1 98.8 27.3 39.1 34.8 32.8 7.3 24.1 69.7 33.0 22.7 C21orf58 ENSG00000160298 "Chromosome 21 open reading frame 58" P58505 21 46300181-46323875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.4;pituitary gland: 20.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 141.9;Enteroendocrine cells: 69.4;Erythroid cells: 80.2;Respiratory ciliated cells: 164.1;Spermatocytes: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 4.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.4" "Cell line enhanced" "Detected in many" "REH: 62.0" "Not detected" "Not detected" "HPA035110, HPA035111" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 14: REH - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nuclear bodies" "HPA035110: AB_10603683, HPA035111: AB_2674468" "unprognostic (2.19e-1)" "unprognostic (6.74e-3)" "unprognostic (2.51e-1)" "unprognostic (6.31e-3)" "unprognostic (1.08e-2)" "prognostic favorable (7.00e-4)" "unprognostic (4.74e-3)" "unprognostic (6.14e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (1.38e-1)" "prognostic favorable (4.20e-4)" "unprognostic (1.27e-1)" "unprognostic (1.01e-10)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "unprognostic (2.51e-1)" "unprognostic (6.07e-2)" 1.5 1.7 1.9 3.6 2.4 13.1 2.0 2.6 2.3 3.5 3.0 3.2 4.7 2.0 0.7 3.9 26.4 1.0 1.3 1.8 1.9 1.5 1.7 4.8 6.3 2.8 4.6 2.6 2.5 1.2 20.7 2.0 2.0 2.9 2.6 2.5 2.3 1.5 1.7 5.3 4.4 1.3 1.8 3.4 3.5 7.1 2.5 12.8 2.1 0.7 3.8 2.1 2.7 3.2 26.0 11.6 30.2 19.0 2.9 4.0 16.7 15.7 5.7 10.8 10.5 5.4 18.6 18.6 3.8 4.4 12.5 20.3 8.1 6.7 3.2 19.9 17.8 29.9 35.2 3.1 0.7 8.6 16.6 1.7 1.4 7.7 1.9 4.0 6.8 45.4 17.4 48.1 8.9 10.6 42.7 11.6 13.0 7.2 5.7 62.0 13.6 16.6 3.4 4.8 24.7 15.4 11.7 8.3 3.7 6.4 20.5 17.1 4.7 6.6 18.4 6.6 9.6 19.3 9.3 8.8 11.6 37.1 17.4 4.4 0.2 0.6 0.4 0.1 0.2 0.1 0.5 0.6 0.0 0.9 0.9 0.7 0.3 0.3 0.1 1.0 0.8 0.5 1.9 2.4 2.6 2.3 1.8 1.9 2.8 4.6 2.0 1.8 2.5 3.2 2.1 3.2 2.6 4.2 3.1 0.9 1.6 7.0 2.8 19.5 6.2 8.8 3.0 0.0 16.6 1.8 27.1 7.7 9.4 13.9 0.0 1.7 17.3 141.9 7.7 2.3 69.4 80.2 2.7 1.0 5.9 5.9 11.7 4.5 2.5 21.4 2.2 1.5 4.0 5.0 2.5 12.8 14.2 1.6 1.9 32.5 5.3 6.2 0.0 0.0 1.3 5.9 5.2 1.5 4.2 1.2 4.1 2.6 4.8 2.0 3.0 0.7 164.1 28.2 0.0 2.6 5.5 80.8 45.3 8.5 1.4 1.4 3.7 3.9 16.8 0.9 C21orf62 "B37, C21orf120, PRED81" ENSG00000205929 "Chromosome 21 open reading frame 62" Q9NYP8 21 32790673-32813743 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 19.7;ovary: 14.2" "Group enriched" "Detected in many" 4 "Cholangiocytes: 44.3;Distal tubular cells: 23.5;Skeletal myocytes: 26.2" "Cancer enriched" "Detected in some" 6 "glioma: 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "AF22: 3.8;RPTEC TERT1: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016899 Enhanced "Secreted - unknown location" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA016899: AB_1845704" "unprognostic (1.31e-1)" "unprognostic (3.84e-2)" "unprognostic (1.23e-1)" "unprognostic (4.37e-3)" "unprognostic (9.56e-2)" "unprognostic (3.05e-3)" "unprognostic (2.95e-2)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.85e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.59e-1)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" 1.6 0.3 1.7 0.4 2.2 0.5 0.1 1.8 2.0 0.0 19.7 0.1 0.1 0.0 8.4 0.2 0.7 0.4 0.2 2.4 4.1 6.9 0.2 0.1 0.2 3.2 7.2 14.2 4.1 0.0 3.4 0.0 2.8 3.6 0.0 1.0 0.1 0.2 0.1 0.2 0.4 0.2 2.0 0.2 0.3 0.3 4.6 0.0 0.1 0.1 1.1 0.0 0.1 5.8 0.0 0.0 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.7 0.2 0.0 0.1 0.3 0.0 1.7 2.2 1.8 2.0 2.4 4.1 3.2 7.2 2.8 2.0 4.6 5.8 0.0 0.0 0.0 2.9 0.5 0.9 0.8 0.4 0.0 5.9 0.0 0.0 0.2 44.3 0.3 5.5 6.2 1.2 1.3 0.1 23.5 0.2 1.5 0.0 0.0 0.8 3.0 0.0 0.8 0.0 0.4 3.6 0.0 0.0 0.0 0.2 2.5 0.2 0.3 0.0 1.4 0.0 0.0 1.3 1.9 0.3 4.1 0.4 3.6 0.0 1.0 5.8 4.1 4.0 4.7 0.0 0.0 1.9 0.0 0.5 0.1 2.6 0.2 7.1 0.0 26.2 1.7 1.0 1.0 0.0 1.0 0.3 1.1 0.2 0.2 0.4 C22orf15 "FLJ36561, N27C7-3" ENSG00000169314 "Chromosome 22 open reading frame 15" Q8WYQ4 22 23762990-23765863 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "fallopian tube: 18.3" "Cell type enriched" "Detected in some" 5 "Respiratory ciliated cells: 198.2" "Cancer enriched" "Detected in single" 4 "endometrial cancer: 1.7" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 1.2;BJ: 1.2;BJ hTERT+: 2.3;hTERT-RPE1: 3.2;MOLT-4: 1.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Secreted in female reproductive system" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (2.37e-2)" "unprognostic (3.28e-3)" "unprognostic (1.28e-1)" "prognostic favorable (8.53e-5)" "unprognostic (1.86e-2)" "unprognostic (2.07e-2)" "unprognostic (4.38e-2)" "unprognostic (6.14e-2)" "unprognostic (3.60e-2)" "unprognostic (7.70e-2)" "unprognostic (4.58e-2)" "unprognostic (2.60e-1)" "unprognostic (9.79e-2)" "unprognostic (2.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.28e-2)" "unprognostic (3.08e-3)" 0.1 0.0 0.3 0.0 0.2 0.3 0.1 0.2 0.2 0.4 0.5 0.2 0.0 0.2 0.0 0.0 18.3 0.2 0.0 0.3 0.6 0.1 0.0 1.8 0.1 1.1 1.6 0.5 0.0 0.0 1.0 0.2 1.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.8 0.2 0.1 2.8 0.3 1.0 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.1 1.2 0.0 0.0 0.0 0.0 1.2 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.3 0.2 0.1 0.1 0.5 0.2 0.0 0.0 0.0 1.0 0.0 0.1 0.3 0.2 0.2 0.2 0.3 0.6 1.1 1.6 1.1 0.8 0.3 0.2 0.0 0.0 1.8 1.3 0.0 0.1 0.0 9.1 0.0 0.5 0.0 0.5 0.1 0.0 15.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 6.0 35.8 0.2 0.2 0.0 0.4 2.3 0.0 0.0 1.4 0.0 0.3 2.5 0.1 0.7 0.1 0.0 0.0 2.0 0.0 16.2 0.3 0.4 3.5 0.0 0.3 0.0 1.0 0.1 0.2 0.0 0.5 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 198.2 1.9 0.0 0.1 3.5 10.9 4.2 0.0 0.3 0.0 1.0 0.5 0.0 0.1 C2CD2 "C21orf25, C21orf258, DKFZP586F0422, TMEM24L" ENSG00000157617 "C2 calcium dependent domain containing 2" Q9Y426 21 41885112-41954018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 126.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 51.6;Cone photoreceptor cells: 83.4;Granulosa cells: 100.0;Theca cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 79.1;SK-BR-3: 44.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030922, HPA030924" Enhanced Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA030922: AB_2673660, HPA030924: AB_10669873" "unprognostic (3.02e-3)" "unprognostic (3.69e-2)" "unprognostic (2.21e-2)" "unprognostic (9.63e-2)" "unprognostic (3.15e-3)" "unprognostic (2.93e-2)" "unprognostic (2.39e-2)" "unprognostic (3.44e-2)" "unprognostic (3.00e-2)" "unprognostic (4.39e-2)" "unprognostic (2.43e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.68e-5)" "unprognostic (1.99e-1)" "unprognostic (4.56e-2)" "unprognostic (1.06e-2)" "unprognostic (1.48e-1)" 39.9 126.3 18.6 8.3 18.0 1.3 23.3 18.4 19.8 12.0 16.9 12.9 4.9 8.3 8.4 10.7 9.4 8.3 7.5 16.4 18.6 10.1 8.6 7.9 9.7 21.8 20.9 18.9 11.3 29.2 7.2 5.2 20.2 17.3 5.8 24.6 10.8 11.5 2.8 15.6 9.0 7.8 20.5 41.4 11.7 3.3 23.4 6.7 8.5 4.1 7.9 12.8 11.4 26.1 13.4 5.5 3.9 8.9 79.1 21.7 15.1 9.3 14.4 5.7 5.2 8.7 15.0 0.2 5.0 18.0 14.0 1.5 13.9 9.7 7.2 0.9 6.2 2.3 7.1 7.1 10.6 1.0 0.0 14.0 8.9 30.3 11.7 12.5 27.1 0.7 8.4 0.1 15.3 1.2 1.9 2.7 21.4 5.7 18.7 1.4 5.7 8.0 8.5 27.8 6.3 2.8 10.1 44.6 8.1 7.6 11.7 5.9 9.3 13.5 1.9 4.5 7.6 5.0 7.9 1.1 39.2 7.7 2.8 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.2 0.1 0.3 0.1 0.5 0.3 0.1 0.3 0.1 0.0 0.3 0.1 18.6 18.0 18.4 19.8 16.4 18.6 21.8 20.9 20.2 20.5 23.4 26.1 24.8 3.2 15.5 20.5 4.4 4.1 9.1 7.6 15.9 51.6 8.2 7.0 3.1 8.6 8.3 3.7 83.4 12.8 4.4 3.4 0.0 5.6 0.3 6.0 6.7 19.3 4.9 5.9 20.3 8.5 4.8 11.9 17.9 8.3 0.0 100.0 46.1 5.2 3.6 1.7 14.4 6.9 6.1 7.0 10.5 0.2 3.7 5.6 1.8 24.4 2.5 3.6 3.1 11.6 18.8 8.1 5.0 2.2 8.1 15.9 3.0 2.5 7.7 36.9 13.1 7.4 17.9 0.1 3.0 14.3 2.6 9.3 2.8 82.4 6.9 16.6 C2orf66 UNQ6411 ENSG00000187944 "Chromosome 2 open reading frame 66" 2 196804417-196809355 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adrenal gland: 3.9;brain: 5.1;pituitary gland: 3.7" "Cell type enriched" "Detected in some" 7 "Early spermatids: 36.9" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 9.0;RT4: 2.2;TIME: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA020869 Uncertain Uncertain Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 36: HEL - Hemostasis" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA020869: AB_1851545" "unprognostic (1.19e-1)" "unprognostic (4.85e-2)" "unprognostic (6.95e-2)" "unprognostic (1.19e-1)" "unprognostic (3.48e-2)" "unprognostic (1.61e-2)" "unprognostic (6.80e-3)" "unprognostic (3.05e-2)" "unprognostic (1.95e-1)" "unprognostic (4.10e-3)" "unprognostic (4.54e-4)" "unprognostic (1.98e-1)" "unprognostic (1.75e-5)" "unprognostic (1.84e-1)" "unprognostic (2.30e-1)" "unprognostic (1.38e-2)" "unprognostic (1.86e-2)" 2.8 3.9 2.1 0.2 1.8 0.1 0.4 1.4 2.2 0.0 1.7 0.3 0.0 0.1 0.4 0.2 0.6 0.3 0.5 2.0 4.2 0.2 0.1 0.3 0.0 2.3 5.1 0.3 0.4 0.1 3.7 0.0 2.9 0.3 0.1 1.8 0.1 0.1 0.0 1.2 0.3 0.0 1.5 0.1 0.2 1.5 2.8 0.1 0.1 0.0 0.1 0.3 0.2 1.6 0.0 0.1 0.2 0.8 0.2 0.2 0.0 0.3 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.4 9.0 0.3 0.1 0.0 0.1 0.8 0.2 1.2 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.4 2.2 0.3 0.0 0.0 0.0 0.2 0.3 0.0 0.1 2.1 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.8 1.4 2.2 2.0 4.2 2.3 5.1 2.9 1.5 2.8 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.9 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 4.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 C2orf69 FLJ38973 ENSG00000178074 "Chromosome 2 open reading frame 69" Q8N8R5 2 199911293-199955935 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 132.1;Spermatocytes: 124.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045225 Approved "Secreted to blood" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA045225: AB_10960841" "unprognostic (6.94e-3)" "unprognostic (1.09e-1)" "unprognostic (7.17e-2)" "unprognostic (3.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (4.39e-3)" "unprognostic (1.92e-2)" "unprognostic (5.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.33e-3)" "unprognostic (1.74e-1)" "unprognostic (1.44e-1)" "unprognostic (3.41e-3)" "unprognostic (8.87e-2)" "unprognostic (1.03e-2)" "unprognostic (5.86e-2)" 9.7 14.1 8.5 6.8 8.7 22.1 7.4 7.7 12.4 5.7 6.3 8.0 8.4 6.4 6.5 6.8 3.8 6.2 6.7 9.6 9.2 8.9 10.0 6.0 7.3 7.7 8.3 4.8 8.2 9.2 4.1 5.3 7.8 6.5 8.0 10.4 6.2 4.7 9.1 6.4 7.4 7.6 8.4 7.0 7.1 14.7 9.3 5.2 6.7 9.8 7.4 6.8 4.0 10.0 16.1 7.2 13.2 18.0 18.2 22.8 22.3 22.6 13.5 15.0 17.7 16.3 11.4 13.2 12.9 16.0 15.9 12.8 14.1 12.0 25.1 19.8 12.8 20.4 12.4 20.8 10.6 20.7 24.2 11.8 10.5 17.2 14.9 8.1 17.0 8.8 14.9 25.5 25.6 13.9 11.6 18.1 19.4 7.1 19.1 11.0 17.2 11.9 14.8 16.4 21.5 9.4 10.9 8.1 17.4 16.9 12.0 17.7 14.9 23.3 19.0 26.2 18.2 16.7 29.0 13.0 18.6 13.1 12.0 5.4 2.7 7.2 3.6 3.5 5.2 3.1 4.0 3.4 2.4 3.0 4.2 4.5 2.3 2.0 2.7 1.3 4.1 2.8 8.5 8.7 7.7 12.4 9.6 9.2 7.7 8.3 7.8 8.4 9.3 10.0 13.5 3.2 5.1 12.4 22.9 38.0 29.8 8.8 9.1 21.8 10.1 3.7 11.4 12.8 7.6 16.5 29.2 13.3 11.0 16.4 27.4 12.8 132.1 7.9 10.2 16.1 18.6 27.8 19.4 18.3 18.0 17.0 13.7 7.1 8.2 14.8 23.6 19.7 11.8 13.5 13.9 16.9 10.2 18.0 32.1 78.1 13.4 13.4 16.0 12.2 14.0 56.5 12.3 12.5 27.0 14.6 9.3 21.8 8.6 24.6 18.1 20.4 11.8 26.5 19.7 14.0 14.9 124.3 44.1 15.7 44.9 9.9 18.1 11.1 17.5 19.5 C2orf92 LINC01125 ENSG00000228486 "Chromosome 2 open reading frame 92" A0A1B0GVN3 2 97664217-97703064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 11.7" "Cell type enhanced" "Detected in some" "Adipocytes: 2.5;Alveolar cells type 2: 7.5;Breast glandular cells: 3.3;Breast myoepithelial cells: 2.7;Club cells: 2.5;Endometrial ciliated cells: 3.7;Endometrial stromal cells: 2.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.6;HDLM-2: 2.0" "Not detected" "Not detected" NA NA "Cluster 43: Testis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (5.53e-2)" "unprognostic (8.76e-2)" "unprognostic (1.65e-2)" "unprognostic (2.08e-1)" "unprognostic (4.81e-2)" "unprognostic (3.09e-3)" "unprognostic (9.29e-2)" "unprognostic (1.22e-2)" "unprognostic (1.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.98e-3)" "unprognostic (2.76e-2)" "unprognostic (7.45e-7)" "unprognostic (5.57e-2)" "unprognostic (1.28e-1)" "unprognostic (3.11e-1)" "unprognostic (5.23e-5)" 1.4 1.3 2.5 0.3 2.6 0.3 1.8 2.7 4.4 1.8 2.6 1.1 0.4 0.9 1.7 0.8 1.2 0.2 1.6 2.5 2.5 1.5 2.6 1.6 0.2 2.6 2.6 0.9 2.0 0.3 1.5 0.3 2.7 2.0 0.4 0.7 1.9 0.6 1.5 2.0 1.3 0.2 2.6 3.0 1.1 11.7 2.6 0.4 3.5 0.0 0.5 0.8 1.3 2.8 0.1 0.0 1.6 0.3 0.7 0.6 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.7 2.0 0.0 0.8 0.2 0.0 0.0 0.5 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.4 0.1 0.0 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.8 0.4 0.6 0.1 0.5 0.7 0.2 1.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.7 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.6 2.7 4.4 2.5 2.5 2.6 2.6 2.7 2.6 2.6 2.8 2.5 0.0 7.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 3.3 2.7 0.0 0.0 2.5 0.0 0.0 0.7 1.6 0.0 0.0 0.6 0.0 3.7 2.7 0.5 0.0 0.0 0.0 1.6 0.6 0.6 0.0 2.3 1.3 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.7 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.9 1.6 0.0 0.0 C3 "ARMD9, C3a, C3b, CPAMD1" ENSG00000125730 "Complement C3" P01024 19 6677704-6730562 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Fatty acid metabolism, Immunity, Inflammatory response, Innate immunity, Lipid metabolism" "Age-related macular degeneration, Disease variant, FDA approved drug targets, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 4761.3" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 4512.2" "Cancer enriched" "Detected in all" 5 "liver cancer: 1213.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "non-classical monocyte: 13.3" "Lineage enriched" "Detected in many" 4 "monocytes: 13.3" "Group enriched" "Detected in many" 7 "BJ hTERT+: 357.8;EFO-21: 738.6;Hep G2: 795.3;HSkMC: 534.8;SiHa: 209.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003563, CAB004209, HPA020432" Enhanced "Secreted to blood" NA NA 1260000000000 200000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB004209: AB_627277, HPA003563: AB_1847117, HPA020432: AB_1847118" "unprognostic (3.26e-3)" "unprognostic (3.91e-1)" "unprognostic (3.92e-1)" "unprognostic (5.98e-3)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "prognostic favorable (8.11e-4)" "unprognostic (1.99e-1)" "unprognostic (9.26e-2)" "unprognostic (5.80e-2)" "unprognostic (8.12e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.63e-2)" "unprognostic (2.49e-2)" "unprognostic (6.03e-3)" "unprognostic (3.88e-1)" 585.2 286.5 46.0 194.3 53.7 1.5 213.9 47.8 46.0 237.5 31.5 128.9 22.9 82.9 41.1 76.4 350.3 354.9 221.6 36.5 81.8 51.4 4761.3 176.0 68.2 143.3 99.2 228.1 182.7 17.9 21.8 17.7 116.4 35.4 76.5 11.7 155.6 57.4 36.6 51.4 156.4 123.0 89.9 7.1 107.9 41.1 103.4 34.1 92.4 52.0 126.4 363.3 101.3 121.9 65.0 23.0 0.0 0.1 10.8 36.0 74.7 5.2 357.8 6.8 12.6 3.6 49.5 1.9 738.6 0.3 54.2 46.6 0.2 43.1 6.9 24.0 0.5 3.1 31.2 795.3 16.3 6.2 9.1 534.8 12.8 60.8 27.3 9.5 0.0 0.0 2.1 0.8 0.2 1.0 0.6 1.6 1.5 0.7 0.1 0.4 5.0 0.3 32.1 6.2 0.5 0.5 209.5 0.1 0.5 0.1 17.2 8.8 3.5 5.7 7.4 4.8 3.6 1.6 4.8 4.5 75.1 4.5 0.3 1.7 1.3 0.6 0.3 2.5 0.2 0.5 0.2 0.1 0.7 0.5 0.2 0.2 3.0 1.3 13.3 0.5 0.1 0.9 46.0 53.7 47.8 46.0 36.5 81.8 143.3 99.2 116.4 89.9 103.4 121.9 36.4 76.9 473.9 0.7 29.4 27.5 14.7 141.5 0.6 0.7 19.5 23.4 14.5 783.5 422.5 16.5 0.0 1.4 2.0 0.2 5.9 494.1 45.9 23.0 63.5 26.2 0.0 209.9 0.4 136.7 1.4 482.2 17.9 57.7 5.1 0.1 124.9 4512.2 34.4 0.0 0.5 0.9 20.3 164.5 44.8 97.5 226.2 45.1 35.6 70.3 14.6 1.2 0.0 0.5 0.6 376.4 0.2 10.9 3.9 13.3 1.9 53.6 177.5 4.6 6.6 20.1 49.1 4.0 7.7 5.2 21.9 2.7 15.0 0.1 0.4 38.2 C3orf85 FLJ22763 ENSG00000241224 "Chromosome 3 open reading frame 85" A0A1B0GTC6 3 109118252-109151401 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 70.4;kidney: 13.9;liver: 19.8" "Cell type enriched" "Detected in some" 9 "Proximal tubular cells: 169.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2900000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (9.10e-2)" "unprognostic (9.48e-3)" "unprognostic (3.80e-4)" "unprognostic (1.15e-1)" "unprognostic (6.70e-2)" 0.1 0.0 0.2 0.4 0.4 0.0 0.0 0.5 0.2 0.0 0.0 5.4 70.4 0.1 1.6 0.0 0.0 0.0 0.0 0.1 0.2 13.9 19.8 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.2 0.1 0.0 0.0 0.0 0.0 64.6 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.5 0.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 169.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 C4A "C4, C4A2, C4A3, C4A4, C4A6, C4B, C4S, CO4, CPAMD2, RG" ENSG00000244731 "Complement C4A (Rodgers blood group)" P0C0L4 6 31982057-32002681 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 115.8;liver: 336.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 46.4;Cardiomyocytes: 8.3;Club cells: 13.6;Fibroblasts: 19.1" "Cancer enhanced" "Detected in many" "liver cancer: 27.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 58.5;HSkMC: 72.8;U-266/70: 17.1;U-266/84: 33.9" "CAB009811, CAB032603, HPA046356, HPA048287, HPA050103" Supported "Secreted to blood" NA NA 342000000 120000000000 "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB009811: AB_2066891, CAB032603: AB_2290613, HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (2.13e-1)" "unprognostic (3.02e-2)" "unprognostic (3.74e-2)" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (3.09e-2)" "unprognostic (2.48e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (3.20e-2)" "unprognostic (5.20e-2)" "unprognostic (3.97e-2)" "unprognostic (8.63e-2)" 27.9 115.8 0.2 10.6 1.6 0.4 15.7 0.3 2.2 12.6 0.2 31.3 7.5 16.9 11.8 2.6 29.9 2.3 21.8 0.5 1.2 43.1 336.8 14.9 4.5 5.8 1.9 57.5 23.0 0.6 20.6 0.5 2.3 11.1 3.7 5.5 14.2 0.0 1.7 1.7 17.0 0.0 0.5 15.3 11.7 4.1 1.7 4.2 44.5 0.0 2.9 23.1 4.1 1.4 0.0 0.3 0.0 0.0 1.0 5.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.7 0.2 0.1 0.1 0.4 0.0 58.5 0.5 0.0 0.3 1.0 0.0 0.0 0.0 72.8 0.0 0.0 0.0 0.5 0.0 0.6 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.9 0.0 0.1 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.2 17.1 33.9 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.3 2.2 0.5 1.2 5.8 1.9 2.3 0.5 1.7 1.4 0.0 9.6 46.4 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 8.3 2.8 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.4 6.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.5 4.4 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 C4B "C4B1, C4B3, C4F, CH, CO4, CPAMD3" ENSG00000224389 "Complement C4B (Chido blood group)" P0C0L5 6 32014795-32035418 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 221.5;liver: 385.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 103.9;Cardiomyocytes: 71.8;Club cells: 22.9;Fibroblasts: 53.9" "Cancer enhanced" "Detected in many" "liver cancer: 33.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 129.8" "HPA046356, HPA048287, HPA050103" Approved "Secreted to blood" NA NA 120000000000 "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (1.29e-1)" "unprognostic (2.99e-2)" "unprognostic (5.50e-3)" "unprognostic (1.30e-1)" "unprognostic (8.09e-2)" "unprognostic (6.24e-2)" "unprognostic (6.09e-2)" "unprognostic (1.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.12e-1)" "unprognostic (6.24e-2)" "unprognostic (6.86e-2)" "unprognostic (1.04e-1)" "unprognostic (3.12e-2)" "unprognostic (1.30e-1)" "unprognostic (3.99e-3)" "unprognostic (1.11e-2)" 29.7 221.5 4.0 0.4 2.5 0.6 15.9 2.5 2.3 10.3 2.4 27.3 2.0 16.6 0.0 2.2 24.0 5.9 22.7 3.2 13.3 39.8 385.2 13.6 2.7 7.1 12.4 56.5 25.1 1.1 20.1 1.6 7.7 10.2 6.0 2.5 21.0 1.2 1.3 1.1 16.6 9.7 9.9 16.3 10.3 3.1 11.8 7.5 49.1 0.2 4.3 18.5 3.7 11.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 21.0 7.8 0.5 0.0 26.2 0.1 0.0 0.0 2.6 0.0 0.0 0.0 129.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.5 2.5 2.3 3.2 13.3 7.1 12.4 7.7 9.9 11.8 11.6 0.0 3.2 103.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 71.8 1.5 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.6 0.0 0.0 0.0 0.2 0.0 53.9 0.0 0.0 1.3 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.1 0.0 0.5 8.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 C4BPA C4BP ENSG00000123838 "Complement component 4 binding protein alpha" P04003 1 207104233-207144972 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 1918.6" "Group enriched" "Detected in many" 14 "Alveolar cells type 1: 493.6;Alveolar cells type 2: 660.8;Hepatocytes: 1020.8" "Cancer enriched" "Detected in many" 7 "liver cancer: 434.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "neutrophil: 29.5" "Lineage enriched" "Detected in single" 137 "granulocytes: 29.5" "Cell line enriched" "Detected in some" 5 "Hep G2: 37.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000926, HPA001578" Enhanced "Secreted to blood" NA NA 30800000000 28000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA000926: AB_1078355, HPA001578: AB_1078354" "unprognostic (3.85e-4)" "unprognostic (9.07e-2)" "unprognostic (2.06e-1)" "prognostic favorable (6.37e-5)" "unprognostic (3.58e-2)" "unprognostic (2.41e-1)" "prognostic favorable (2.24e-4)" "unprognostic (3.64e-2)" "unprognostic (1.94e-1)" "unprognostic (5.90e-4)" "unprognostic (4.47e-2)" "unprognostic (2.58e-1)" "unprognostic (5.51e-7)" "unprognostic (9.74e-2)" "unprognostic (2.52e-2)" "unprognostic (6.92e-2)" "unprognostic (2.66e-1)" 1.4 0.7 0.4 2.5 0.2 0.1 4.5 0.7 0.2 6.3 0.0 1.7 0.0 4.5 0.0 0.1 1.0 3.2 0.2 0.1 0.7 0.6 1918.6 173.3 0.3 0.4 0.2 1.5 9.6 0.2 0.1 0.7 0.5 0.1 0.8 0.0 1.1 0.0 0.0 0.0 0.8 0.1 0.1 1.2 0.4 0.3 0.3 0.0 0.1 0.0 1.1 0.1 0.0 0.4 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 37.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 7.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.7 0.2 0.1 0.7 0.4 0.2 0.5 0.1 0.3 0.4 0.0 493.6 660.8 0.0 3.7 0.0 0.0 0.2 0.0 0.0 2.7 0.4 0.2 41.5 22.5 0.0 0.0 0.0 0.0 3.2 0.0 11.2 0.3 18.0 7.6 1.9 0.0 21.5 0.7 18.7 0.0 1.1 0.0 48.8 3.8 0.0 22.1 1020.8 0.2 0.0 1.4 0.3 0.0 39.2 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 5.6 32.0 0.0 0.0 0.3 0.1 0.1 3.6 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 3.9 16.7 0.2 1.4 C4BPB C4BP ENSG00000123843 "Complement component 4 binding protein beta" P20851 1 207088860-207099993 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 471.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 597.6" "Cancer enriched" "Detected in many" 19 "liver cancer: 83.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 16 "CACO-2: 116.4;HeLa: 46.2;Hep G2: 151.6;OE19: 57.1" "Not detected" "Not detected" "HPA000925, HPA051620" Approved Uncertain "Golgi apparatus" "Secreted to blood" NA NA 265000000000 1100000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "HPA000925: , HPA051620: AB_2681554" "unprognostic (1.73e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-1)" "unprognostic (2.07e-3)" "unprognostic (1.72e-1)" "unprognostic (2.54e-2)" "unprognostic (4.58e-3)" "unprognostic (9.49e-2)" "unprognostic (1.37e-1)" "unprognostic (4.25e-1)" "unprognostic (6.39e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.05e-2)" "unprognostic (8.25e-2)" 3.0 0.1 0.0 3.4 0.0 0.0 1.8 0.0 0.1 2.8 0.0 3.6 3.8 0.1 0.0 0.2 0.5 3.1 0.1 0.0 0.0 0.4 471.3 1.5 0.4 0.0 0.0 44.2 9.1 0.0 0.0 6.2 0.1 0.0 1.8 0.0 0.5 0.0 0.1 0.2 4.4 0.6 0.0 0.4 8.4 0.7 0.0 0.1 0.0 0.1 0.2 0.4 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.4 5.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 46.2 151.6 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.6 0.3 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 12.8 2.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 7.3 2.2 0.5 54.3 3.2 0.0 0.0 1.0 0.2 10.2 1.9 11.4 4.1 0.7 0.1 0.8 1.8 8.0 0.1 88.8 0.3 3.4 5.6 0.8 0.0 0.3 9.7 597.6 2.1 0.0 0.2 5.6 0.0 13.1 0.3 2.8 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.1 69.2 15.9 0.0 0.1 0.2 4.3 0.0 2.2 0.0 0.0 1.1 0.4 0.1 0.4 0.0 0.0 0.1 1.1 143.8 4.8 0.1 C4orf48 ENSG00000243449 "Chromosome 4 open reading frame 48" Q5BLP8 4 2041993-2043970 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.9;choroid plexus: 62.6;pituitary gland: 74.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 412.4;Paneth cells: 484.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 158.3;NB-4: 117.3;PC-3: 343.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052447 Uncertain Approved Cytosol "Secreted to blood" NA NA 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA052447: AB_2681837" "unprognostic (7.96e-2)" "unprognostic (2.57e-3)" "unprognostic (2.08e-1)" "unprognostic (3.20e-2)" "unprognostic (4.01e-2)" "unprognostic (8.26e-2)" "unprognostic (4.85e-3)" "unprognostic (2.51e-3)" "unprognostic (2.28e-3)" "unprognostic (1.80e-1)" "unprognostic (1.95e-2)" "unprognostic (5.55e-2)" "unprognostic (3.42e-2)" "unprognostic (5.38e-3)" "unprognostic (2.68e-1)" "unprognostic (5.55e-2)" "unprognostic (3.17e-3)" 13.5 18.3 50.0 4.6 68.4 2.7 9.6 71.0 66.6 5.2 62.6 20.4 2.7 5.5 0.2 4.3 7.8 0.4 8.2 49.4 60.8 20.2 4.0 7.9 1.3 81.5 63.2 6.6 18.9 2.4 74.5 2.1 58.6 7.1 0.9 0.2 9.2 1.4 1.2 3.1 16.3 0.6 67.8 18.5 11.9 56.1 60.3 0.3 9.3 0.0 0.6 6.8 2.9 97.9 33.4 27.1 5.3 24.9 2.4 3.9 35.3 31.2 6.0 5.6 5.3 18.6 19.6 4.4 29.2 1.2 10.4 9.2 0.6 3.5 1.7 20.1 158.3 10.5 15.8 10.7 5.2 21.7 70.3 3.0 5.9 1.2 0.0 1.8 5.9 17.9 35.1 0.1 3.9 20.6 24.6 117.3 15.8 1.8 343.1 56.1 8.3 11.2 5.0 12.3 42.7 60.0 15.3 0.7 47.7 0.5 8.3 10.3 26.5 14.7 31.9 11.0 35.3 23.8 22.4 0.4 14.6 13.2 20.8 88.5 451.6 431.5 123.6 325.6 127.5 187.7 157.2 138.3 270.0 167.9 89.1 92.9 349.2 29.6 290.7 301.1 199.8 192.8 50.0 68.4 71.0 66.6 49.4 60.8 81.5 63.2 58.6 67.8 60.3 97.9 13.3 0.0 1.9 8.8 58.1 21.9 6.6 13.2 7.4 12.0 147.0 139.8 10.6 20.0 14.2 200.5 0.0 8.0 52.8 412.4 70.5 320.8 97.1 326.7 92.6 42.1 235.1 30.7 5.6 222.7 116.5 47.7 35.7 107.3 107.5 209.0 123.1 11.9 235.5 18.5 8.2 154.2 44.7 272.1 113.3 350.5 19.3 158.9 327.3 7.5 205.2 78.8 20.6 6.0 41.1 198.2 484.2 28.2 84.1 10.9 223.7 7.9 28.8 15.0 13.1 1.7 53.2 99.7 193.2 5.7 10.1 13.1 73.9 50.9 117.1 11.1 C5 "C5a, C5b, CPAMD4" ENSG00000106804 "Complement C5" P01031 9 120952335-121050275 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Inflammatory response, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "liver: 433.7" "Cell type enriched" "Detected in many" 16 "Hepatocytes: 538.3" "Cancer enriched" "Detected in many" 17 "liver cancer: 73.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 28.4;Hep G2: 30.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029339 Supported "Secreted to blood" NA NA 113000000000 39000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA029339: AB_10601125" "unprognostic (2.51e-1)" "unprognostic (5.88e-3)" "unprognostic (2.50e-3)" "unprognostic (1.57e-2)" "unprognostic (5.05e-2)" "unprognostic (9.52e-3)" "prognostic favorable (9.43e-4)" "unprognostic (1.83e-1)" "unprognostic (3.19e-2)" "unprognostic (1.55e-1)" "unprognostic (2.35e-2)" "unprognostic (4.41e-2)" "unprognostic (1.46e-5)" "unprognostic (5.91e-2)" "unprognostic (1.20e-1)" "unprognostic (3.67e-2)" "unprognostic (2.75e-1)" 2.9 1.7 2.5 1.1 3.4 2.2 2.5 2.4 2.6 3.0 3.5 2.8 3.9 2.7 2.7 1.6 3.0 1.5 1.3 2.2 2.6 4.8 433.7 7.0 2.1 2.9 2.9 3.3 14.9 2.6 3.1 0.9 3.2 3.2 1.6 3.5 1.4 2.2 0.5 3.8 3.9 1.9 2.8 1.5 5.8 1.6 2.8 1.2 2.0 1.2 1.7 2.6 2.1 4.5 1.6 28.4 6.4 11.3 8.0 9.2 0.2 3.4 3.5 0.9 2.0 0.8 2.8 4.1 0.1 1.8 3.8 11.0 0.3 0.3 1.5 0.9 0.0 1.8 1.5 30.4 1.5 1.0 0.7 4.1 0.5 2.0 3.7 1.8 1.0 1.6 0.7 3.8 2.2 5.6 0.4 0.2 1.7 7.0 10.9 2.5 2.8 0.4 1.7 0.8 1.6 6.5 1.6 0.0 2.7 4.4 2.2 3.7 1.3 2.8 0.2 7.5 3.4 2.3 1.8 1.7 2.2 3.8 6.8 0.0 0.3 0.4 0.0 0.0 0.2 0.3 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 3.4 2.4 2.6 2.2 2.6 2.9 2.9 3.2 2.8 2.8 4.5 0.8 6.4 28.6 30.0 3.5 1.0 1.0 0.5 1.8 4.8 2.2 1.3 0.8 32.9 7.1 1.8 0.0 0.1 0.1 0.4 1.9 0.2 1.8 1.1 2.2 1.4 0.0 12.0 7.3 0.4 0.0 2.9 2.0 0.8 0.0 3.1 7.5 538.3 1.9 6.7 9.4 1.0 0.0 16.3 1.0 2.8 3.1 3.5 0.0 6.5 2.3 3.2 2.1 25.6 25.4 0.7 3.8 9.1 0.1 0.7 1.0 6.8 3.8 2.6 0.0 4.0 1.6 7.5 2.5 2.0 1.3 0.0 1.4 2.8 2.0 0.6 C5AR1 "C5A, C5AR, C5R1, CD88" ENSG00000197405 "Complement C5a receptor 1" P21730 19 47290023-47322066 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 125.5;lymphoid tissue: 84.8" "Group enriched" "Detected in many" 4 "Hofbauer cells: 130.9;Kupffer cells: 228.3;Langerhans cells: 122.4;Macrophages: 446.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 394.0" "Group enriched" "Detected in many" 42 "granulocytes: 394.0;monocytes: 115.9" "Cell line enhanced" "Detected in some" "A549: 3.9;CAPAN-2: 4.1;HMC-1: 4.7;U-87 MG: 6.2;U-937: 6.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB002720, HPA014520, HPA048012" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" Vesicles "CAB002720: , HPA014520: AB_1846337, HPA048012: " "unprognostic (5.95e-2)" "prognostic favorable (4.71e-4)" "unprognostic (1.70e-2)" "unprognostic (1.25e-1)" "unprognostic (4.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-2)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (9.55e-4)" "unprognostic (2.02e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.96e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.82e-2)" "unprognostic (6.54e-2)" 72.7 18.2 3.3 84.8 3.1 125.5 8.5 2.4 9.0 11.8 21.6 9.8 2.5 7.5 1.4 8.3 23.9 38.8 11.7 3.9 8.2 9.7 18.0 43.1 11.5 8.9 6.9 5.0 8.9 4.8 51.8 31.8 8.4 5.3 4.2 4.4 5.1 2.5 1.9 2.3 5.8 28.1 5.7 38.2 7.2 2.6 10.5 7.1 3.6 5.8 4.3 37.1 4.6 11.6 1.0 3.9 0.1 0.1 0.7 0.2 0.6 0.7 0.5 0.2 0.1 0.2 4.1 0.3 0.7 0.9 0.4 1.4 0.2 0.5 0.2 0.7 0.5 0.1 3.8 0.6 0.4 1.5 4.7 0.3 2.2 0.4 0.3 0.6 0.0 0.2 0.2 1.7 0.1 1.1 0.2 2.5 1.2 0.2 0.3 0.2 0.1 0.3 1.3 0.9 0.0 0.0 0.3 0.3 0.6 0.5 0.2 2.2 0.0 0.1 2.1 0.3 0.1 0.2 0.3 0.3 6.2 6.5 0.2 41.6 53.8 38.8 0.4 80.4 0.3 0.4 0.3 0.2 6.1 0.6 0.3 0.3 394.0 0.5 115.9 1.1 0.3 19.3 3.3 3.1 2.4 9.0 3.9 8.2 8.9 6.9 8.4 5.7 10.5 11.6 4.4 3.2 20.8 0.0 5.1 5.1 1.0 3.4 2.8 1.0 2.1 4.4 2.9 1.5 15.3 1.8 2.1 0.8 1.5 1.6 3.9 0.0 1.3 17.3 1.8 6.3 0.0 0.4 1.5 0.0 1.5 5.3 1.1 4.6 25.2 0.1 2.9 8.3 130.9 0.0 0.6 0.8 4.1 228.3 122.4 1.3 0.6 446.7 5.4 5.6 56.3 0.2 0.0 1.0 0.3 0.1 0.1 0.0 4.9 0.5 0.7 1.3 40.7 4.3 13.1 4.1 2.8 0.5 0.9 1.4 3.0 1.5 3.3 0.0 1.3 0.5 C5orf46 "MGC23985, SSSP1" ENSG00000178776 "Chromosome 5 open reading frame 46" Q6UWT4 5 147880726-147906538 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "salivary gland: 181.8;skin 1: 113.1" "Group enriched" "Detected in some" 12 "Early spermatids: 320.9;Late spermatids: 189.9" "Cancer enhanced" "Detected in many" "renal cancer: 8.3" "Region enriched" "Detected in single" 10 "cerebellum: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 54.2;PC-3: 90.8;SiHa: 20.2;U-2 OS: 58.2;U-251 MG: 23.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058999, HPA079692" Supported Approved "Nuclear speckles,Mitochondria" "Secreted in other tissues" NA NA 54000 "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Mitochondria "HPA058999: , HPA079692: " "unprognostic (1.72e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.26e-4)" "unprognostic (9.75e-3)" "unprognostic (2.95e-3)" "unprognostic (1.69e-3)" "unprognostic (1.99e-2)" "unprognostic (3.08e-2)" "unprognostic (2.22e-1)" "unprognostic (4.96e-2)" "unprognostic (2.86e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.75e-9)" "unprognostic (6.48e-3)" "unprognostic (3.47e-2)" "unprognostic (6.01e-2)" "unprognostic (2.79e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 13.5 2.3 0.1 1.6 0.7 0.4 0.0 0.1 0.4 0.4 0.0 0.2 9.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.2 0.2 0.9 0.0 0.6 181.8 0.1 0.8 113.1 0.0 3.2 0.0 0.0 0.0 19.2 0.0 0.3 0.2 0.1 0.3 0.0 3.6 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 2.4 1.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.0 0.3 0.0 0.6 0.0 0.2 0.2 0.0 4.6 0.2 0.0 0.0 0.0 0.0 1.1 0.0 8.9 54.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 20.2 0.3 0.3 11.1 0.0 0.0 0.0 10.0 58.2 0.8 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 9.2 3.7 11.0 15.7 0.2 1.8 0.0 0.5 0.2 0.0 0.0 15.9 320.9 0.7 0.4 0.3 0.0 0.0 0.0 3.3 0.6 0.2 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 189.9 1.8 0.2 3.6 0.0 0.6 7.7 0.0 0.0 0.0 4.2 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 1.1 0.8 0.0 20.6 1.4 0.1 0.0 0.0 0.2 C6 ENSG00000039537 "Complement C6" P13671 5 41142116-41261438 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "liver: 665.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 127.2;Hepatocytes: 376.9;Late spermatids: 54.8;Leydig cells: 120.2;Respiratory ciliated cells: 58.0" "Group enriched" "Detected in many" 7 "liver cancer: 49.0;pancreatic cancer: 12.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 4.5;ASC TERT1: 6.2;HSkMC: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043823, CAB069427" Enhanced "Secreted to blood" NA NA 45000000000 9200000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB069427: AB_1614336, HPA043823: AB_10960262" "unprognostic (9.79e-2)" "unprognostic (1.96e-2)" "unprognostic (5.94e-3)" "unprognostic (3.02e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (1.12e-3)" "unprognostic (4.66e-2)" "unprognostic (3.72e-2)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (3.04e-3)" "prognostic favorable (4.31e-4)" "unprognostic (2.69e-4)" "unprognostic (1.61e-1)" "unprognostic (1.40e-2)" "unprognostic (3.51e-2)" 12.8 1.1 0.2 0.0 0.2 0.0 5.4 0.2 0.1 0.8 1.6 0.8 0.9 0.4 0.9 0.3 43.9 12.0 57.1 0.2 0.6 4.4 665.9 3.2 0.4 0.0 1.7 6.2 42.7 0.1 0.7 2.8 0.2 0.9 0.6 0.0 0.9 0.6 0.6 0.6 1.4 0.9 0.1 0.3 2.2 4.2 0.8 0.6 2.0 0.7 0.5 0.9 0.6 0.6 0.0 0.0 0.0 0.0 4.5 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.2 0.6 0.0 1.7 0.2 0.1 0.8 0.6 0.8 0.0 0.0 0.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 20.9 127.2 7.5 0.0 0.0 0.0 0.1 0.3 0.0 9.3 11.3 37.5 0.8 0.9 0.0 8.0 1.4 0.4 0.0 6.7 0.0 0.7 0.0 0.1 5.0 376.9 0.0 0.0 2.7 1.0 0.0 9.7 0.3 54.8 120.2 0.2 0.0 0.0 0.0 0.0 0.0 1.0 1.3 0.5 1.3 0.4 0.0 0.0 11.6 0.8 58.0 0.0 0.0 0.2 0.4 0.4 0.1 0.0 0.0 0.0 0.4 0.5 0.6 0.0 C6orf120 bA160E12.4 ENSG00000185127 "Chromosome 6 open reading frame 120" Q7Z4R8 6 169702190-169704856 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 116.9;Late spermatids: 272.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039626 Uncertain "Secreted to blood" NA NA 620000 "Cluster 26: Non-specific - Mitochondria" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "HPA039626: AB_10673361" "unprognostic (2.98e-2)" "prognostic unfavorable (2.26e-4)" "unprognostic (3.43e-2)" "unprognostic (1.03e-2)" "unprognostic (1.13e-1)" "unprognostic (4.30e-3)" "prognostic unfavorable (9.52e-5)" "unprognostic (1.78e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.56e-1)" "unprognostic (1.30e-1)" "unprognostic (1.63e-1)" "unprognostic (6.21e-3)" "unprognostic (2.88e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-3)" 21.6 16.6 10.2 14.5 10.7 7.7 15.2 10.8 11.5 13.1 9.8 15.5 16.3 11.2 9.3 13.4 10.3 13.1 9.6 10.6 10.6 19.3 28.0 10.6 16.4 8.8 10.8 15.6 14.2 12.0 6.1 20.0 9.5 12.0 14.4 26.3 13.7 12.0 13.8 9.0 15.9 13.4 10.7 13.7 14.8 8.7 11.2 12.4 10.4 13.2 15.5 15.2 6.7 12.2 13.9 10.9 26.2 40.1 71.4 59.3 29.6 28.5 40.9 23.3 27.2 14.9 12.7 11.8 22.4 35.0 38.7 20.8 17.2 26.1 38.9 20.0 41.6 16.8 10.5 31.4 50.6 28.2 25.7 73.2 21.0 27.8 32.0 40.8 28.6 26.7 45.0 32.8 40.6 25.1 15.3 19.3 22.4 24.3 12.7 11.1 14.4 32.0 28.9 15.3 10.6 24.0 23.7 14.9 19.6 29.7 24.9 36.7 31.8 9.8 19.2 52.3 19.6 42.2 69.3 16.7 32.5 25.7 26.3 6.2 7.9 7.1 3.2 7.6 4.3 3.2 4.7 5.6 6.3 4.9 6.2 5.2 4.2 3.1 6.0 2.1 3.4 3.9 10.2 10.7 10.8 11.5 10.6 10.6 8.8 10.8 9.5 10.7 11.2 12.2 11.3 16.0 5.3 7.2 14.1 9.8 12.6 9.9 12.0 15.3 12.5 9.4 8.8 5.7 10.3 14.7 25.0 27.5 13.2 20.2 9.8 10.6 116.9 9.7 18.5 9.7 14.3 18.3 9.5 15.8 31.6 19.5 16.3 10.8 9.5 11.3 8.9 18.9 16.6 8.4 12.9 12.7 14.2 16.9 6.5 272.5 17.7 13.6 19.6 1.9 15.2 28.6 10.3 11.1 10.3 10.9 10.3 11.7 18.8 13.1 22.4 12.7 12.4 24.6 0.0 10.3 10.8 15.4 12.3 12.6 10.2 29.0 10.9 9.2 12.9 14.7 C6orf15 STG ENSG00000204542 "Chromosome 6 open reading frame 15" Q6UXA7 6 31111223-31112575 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 5.5;lymphoid tissue: 3.5;skin 1: 6.7" "Cell type enriched" "Detected in some" 14 "Breast glandular cells: 73.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "RH-30: 13.4;U-2 OS: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA001436 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 30: Mammary glandular cells - Lactation" "HPA001436: AB_2243752" "unprognostic (2.73e-2)" "unprognostic (5.39e-2)" "unprognostic (1.46e-2)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-1)" "unprognostic (1.77e-1)" "unprognostic (3.35e-1)" "unprognostic (3.42e-2)" "unprognostic (1.71e-2)" "unprognostic (1.72e-1)" "unprognostic (1.90e-1)" "unprognostic (1.34e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 3.5 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 2.3 0.0 1.3 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 C6orf58 LEG1 ENSG00000184530 "Chromosome 6 open reading frame 58" Q6P5S2 6 127519455-127591820 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 612.7;salivary gland: 2257.3" "Group enriched" "Detected in some" 12 "Early spermatids: 14.3;Gastric mucus-secreting cells: 41.3" "Group enriched" "Detected in some" 6 "pancreatic cancer: 17.1;stomach cancer: 14.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 2.0;RPMI-8226: 2.8;WM-115: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036263, HPA041449" Enhanced "Secreted to digestive system" NA NA 30000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA036263: AB_10673349, HPA041449: AB_2677486" "unprognostic (1.49e-1)" "unprognostic (8.55e-2)" "unprognostic (2.71e-1)" "unprognostic (5.69e-2)" "unprognostic (3.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (3.26e-2)" "unprognostic (7.72e-3)" "unprognostic (1.69e-1)" "unprognostic (6.62e-4)" "unprognostic (2.10e-2)" "unprognostic (2.31e-1)" "unprognostic (1.53e-2)" "unprognostic (8.99e-3)" 0.1 0.6 0.0 0.0 0.4 0.0 0.3 0.0 0.3 0.1 0.1 0.1 612.7 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.1 1.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 2257.3 0.0 0.2 0.0 0.2 0.1 0.0 0.3 268.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.2 2.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 2.8 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 14.3 0.1 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.2 41.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 2.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.8 0.7 0.0 0.1 0.3 0.0 0.2 0.0 0.3 C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 578.4;Hepatic stellate cells: 662.5;Leydig cells: 1058.5;Sertoli cells: 309.0;Theca cells: 503.1" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 116.5;HHSteC: 155.1;HSkMC: 212.1;SH-SY5Y: 146.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" 470.9 607.7 2.6 21.7 3.5 0.2 46.4 2.6 9.6 118.5 13.6 165.3 19.3 124.6 163.6 52.9 377.3 211.7 558.7 2.8 2.5 298.1 110.6 206.7 99.2 4.4 2.7 735.4 149.8 15.0 23.1 359.2 3.0 101.6 32.5 1.5 18.0 105.7 4.3 12.6 139.8 256.3 4.3 138.2 120.2 28.0 3.0 32.2 105.1 1.6 22.5 122.1 118.3 3.0 0.0 0.0 0.0 0.0 116.5 16.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 155.1 0.0 0.0 212.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 146.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.5 2.6 9.6 2.8 2.5 4.4 2.7 3.0 4.3 3.0 3.0 7.9 6.4 4.1 0.0 1.4 0.6 0.5 0.0 1.8 2.1 1.2 0.3 56.7 7.2 2.5 0.0 0.0 0.2 0.1 0.4 0.0 0.2 4.7 0.5 7.9 127.6 54.8 26.7 0.1 1.3 0.1 578.4 0.0 0.2 1.3 2.7 662.5 8.3 0.5 43.7 0.3 1.3 0.0 14.5 4.2 29.8 1058.5 1.5 0.0 58.1 0.6 3.7 0.0 0.0 0.0 0.9 0.9 18.0 1.0 1.3 0.2 0.1 0.0 0.9 309.0 2.2 23.7 2.6 2.5 6.5 0.6 0.3 1.2 503.1 3.0 0.8 C7orf25 MGC2821 ENSG00000136197 "Chromosome 7 open reading frame 25" Q9BPX7 7 42908726-42912305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.7;Cone photoreceptor cells: 4.2;Excitatory neurons: 4.6;Inhibitory neurons: 4.7;Oligodendrocytes: 7.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 36.6" "Lineage enriched" "Detected in all" 15 "granulocytes: 36.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020120, HPA049635" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "HPA020120: AB_1845755, HPA049635: AB_2680837" "unprognostic (6.29e-2)" "unprognostic (1.55e-1)" "unprognostic (1.56e-2)" "unprognostic (4.83e-2)" "unprognostic (1.13e-3)" "unprognostic (2.23e-2)" "unprognostic (5.23e-2)" "unprognostic (3.29e-1)" "unprognostic (1.66e-2)" "unprognostic (1.73e-1)" "unprognostic (5.25e-2)" "unprognostic (2.34e-1)" "unprognostic (1.26e-2)" "unprognostic (1.26e-1)" "unprognostic (2.66e-1)" "unprognostic (3.87e-2)" "unprognostic (3.05e-3)" 1.5 1.6 2.4 0.6 2.9 0.7 2.0 2.6 4.5 1.6 1.7 1.6 0.5 1.7 3.2 1.6 2.0 1.9 2.1 2.8 3.2 2.7 1.6 1.5 1.6 3.4 3.0 2.2 1.7 3.1 1.4 2.0 3.5 2.6 1.0 1.9 1.6 2.8 1.7 1.4 1.2 1.9 1.9 1.8 1.9 3.7 2.7 1.6 2.7 1.9 1.2 1.2 0.9 4.5 2.7 8.5 2.2 3.7 2.9 2.0 2.5 5.9 2.0 3.4 3.0 4.9 3.9 7.4 3.7 5.2 4.3 4.1 1.7 5.0 4.2 3.3 7.3 4.0 8.2 3.2 6.2 3.2 2.2 2.9 3.4 3.3 3.3 1.4 2.6 4.8 5.0 1.5 3.3 6.1 1.7 2.5 3.0 1.7 9.8 1.7 2.8 3.7 2.1 6.9 2.8 3.9 8.3 2.9 2.7 3.3 3.3 2.1 7.3 3.6 3.8 4.3 3.3 4.0 9.1 2.2 3.7 3.5 8.3 36.6 1.6 15.7 1.5 2.0 2.3 2.2 1.0 1.5 1.0 1.6 1.6 1.7 8.8 2.2 2.3 0.8 0.8 1.1 2.4 2.9 2.6 4.5 2.8 3.2 3.4 3.0 3.5 1.9 2.7 4.5 0.4 0.0 1.1 2.3 0.7 0.3 0.4 0.1 0.6 0.9 0.4 0.5 0.6 0.0 0.1 3.7 4.2 0.7 0.3 0.1 1.9 0.9 0.1 0.4 0.6 0.7 0.0 0.4 4.6 1.1 0.4 0.6 0.0 0.2 0.0 0.6 1.1 0.5 0.2 0.0 4.7 0.2 0.0 0.0 0.4 0.3 0.6 1.2 0.0 2.8 0.3 0.7 2.1 3.0 7.9 0.9 0.3 0.7 0.2 0.3 0.7 1.5 1.0 0.4 0.0 0.3 0.8 1.7 1.3 0.4 0.4 0.8 0.5 1.0 0.2 0.1 C7orf26 MGC2718 ENSG00000146576 "Chromosome 7 open reading frame 26" Q96N11 7 6590021-6608726 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042899, HPA052175" Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Nucleoli, Intermediate filaments, Cytosol" "HPA042899: AB_2678218, HPA052175: AB_2681750" "unprognostic (4.85e-2)" "unprognostic (6.87e-2)" "unprognostic (4.51e-2)" "unprognostic (2.50e-2)" "unprognostic (2.18e-2)" "unprognostic (5.22e-2)" "unprognostic (4.28e-3)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "prognostic favorable (6.95e-5)" "unprognostic (4.72e-2)" "unprognostic (2.26e-3)" "unprognostic (4.41e-1)" "unprognostic (1.03e-2)" "unprognostic (3.40e-3)" "unprognostic (1.55e-1)" 18.1 18.9 16.9 12.2 18.2 21.3 18.9 15.9 18.5 23.0 15.0 21.6 12.6 23.3 6.5 16.5 22.2 9.3 17.6 16.3 16.2 19.6 21.5 17.2 17.3 18.8 17.2 19.9 21.7 10.1 17.0 7.2 16.9 22.9 7.1 3.8 16.6 9.8 21.9 21.4 18.6 11.1 16.0 27.2 20.0 17.3 17.3 18.5 19.0 10.2 10.9 20.9 17.1 20.4 21.5 17.6 12.0 28.5 19.3 10.7 15.8 12.6 10.9 17.8 10.9 16.5 8.7 25.2 16.0 9.4 33.7 23.3 16.2 11.5 8.1 9.9 23.3 9.4 11.5 17.6 22.5 22.7 29.0 12.4 17.0 10.7 11.2 9.4 19.6 26.7 25.1 18.6 10.7 36.1 19.9 46.9 24.0 10.6 23.2 40.1 9.5 21.5 11.6 18.5 15.7 29.2 12.2 39.9 17.3 12.5 18.3 33.8 14.2 14.7 48.2 16.3 27.9 22.5 23.8 23.8 9.9 24.9 44.3 0.5 1.5 2.2 2.0 1.5 2.6 1.7 2.4 2.6 1.1 1.6 2.4 2.0 1.4 1.6 1.6 2.9 2.7 0.9 16.9 18.2 15.9 18.5 16.3 16.2 18.8 17.2 16.9 16.0 17.3 20.4 12.9 9.6 8.6 11.1 13.7 15.2 8.8 4.6 13.1 7.1 14.2 14.5 6.0 12.8 6.1 1.8 6.2 11.6 23.6 11.8 0.0 8.9 8.2 9.9 12.6 12.8 12.6 4.2 9.5 10.2 10.6 11.2 10.7 8.9 1.3 16.0 12.5 7.4 13.4 5.0 8.3 12.5 8.2 11.3 10.2 3.5 8.1 12.9 7.2 7.5 8.4 6.7 18.6 9.5 13.2 10.2 9.8 8.6 10.9 10.9 8.5 8.0 5.3 6.5 6.6 12.0 14.5 11.9 13.5 11.7 12.8 9.7 17.5 14.0 11.6 7.6 C7orf57 ENSG00000164746 "Chromosome 7 open reading frame 57" Q8NEG2 7 48035511-48061304 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0;choroid plexus: 6.4;fallopian tube: 13.9" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 52.7;Respiratory ciliated cells: 127.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 3.4;hTERT-HME1: 5.5;U-266/70: 3.2;U-698: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021286 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" "HPA021286: AB_1845760" "unprognostic (1.74e-2)" "unprognostic (4.82e-2)" "unprognostic (3.13e-2)" "unprognostic (1.28e-2)" "unprognostic (2.77e-3)" "unprognostic (3.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.32e-1)" "unprognostic (3.29e-1)" "unprognostic (1.37e-1)" "unprognostic (4.98e-2)" "unprognostic (2.88e-1)" "unprognostic (3.93e-5)" "unprognostic (5.17e-3)" "unprognostic (6.18e-2)" "unprognostic (3.42e-3)" "unprognostic (1.20e-1)" 0.0 0.0 0.7 0.0 0.8 0.2 0.1 0.5 0.3 0.4 6.4 0.0 0.1 0.4 0.0 0.8 13.9 0.0 0.1 0.7 0.9 0.1 0.0 2.2 0.0 4.0 3.8 0.0 0.0 0.6 0.2 0.0 2.3 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 3.7 0.9 0.0 0.2 0.0 0.1 0.0 0.4 2.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.0 1.3 0.0 0.1 0.1 3.4 0.2 0.0 0.5 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.3 0.5 0.2 0.3 3.2 0.5 1.9 0.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.5 0.3 0.7 0.9 4.0 3.8 2.3 2.9 0.9 2.0 0.0 0.0 3.0 0.3 0.1 0.0 0.0 4.7 0.0 0.0 0.0 0.1 1.0 0.0 15.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 5.9 52.7 0.6 0.2 0.0 0.0 0.5 0.0 0.1 0.6 0.0 1.1 2.5 0.0 0.0 0.0 0.1 0.0 0.5 0.0 6.1 0.0 0.4 3.5 0.0 0.3 0.0 0.0 0.0 1.1 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 127.6 0.9 0.0 0.0 2.7 16.1 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 C7orf61 IMAGE:4839025 ENSG00000185955 "Chromosome 7 open reading frame 61" Q8IZ16 7 100456620-100464260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 68.4" "Group enriched" "Detected in many" 20 "Early spermatids: 588.7;Late spermatids: 349.4" "Cancer enriched" "Detected in some" 5 "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 25.2;NB-4: 9.6;TIME: 14.9" HPA060395 Enhanced Approved Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA060395: AB_2684274" "unprognostic (1.88e-1)" "unprognostic (5.02e-1)" "unprognostic (1.26e-2)" "unprognostic (7.70e-5)" "unprognostic (1.65e-1)" "unprognostic (2.63e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (4.26e-1)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (2.53e-1)" "unprognostic (6.39e-13)" "unprognostic (9.54e-2)" "unprognostic (2.93e-1)" "unprognostic (1.33e-2)" "unprognostic (1.24e-2)" 1.3 0.6 11.5 0.5 14.7 1.4 0.9 12.5 13.4 2.0 7.4 1.6 0.0 0.9 0.3 0.9 1.4 0.5 1.2 11.0 12.4 1.0 0.8 1.6 0.8 13.7 13.3 3.0 0.3 0.2 2.9 0.6 13.1 1.5 0.1 1.9 0.5 0.6 0.5 0.8 0.9 0.2 11.1 2.6 0.7 68.4 12.7 0.8 1.1 0.6 0.3 1.1 1.3 16.3 1.0 0.2 0.8 0.9 0.9 2.2 0.3 0.4 1.5 0.2 0.8 1.1 0.5 0.7 1.7 0.9 1.4 0.7 0.3 0.0 0.6 1.0 1.7 1.4 2.2 0.0 1.2 0.5 0.4 0.3 0.4 0.9 1.4 2.4 25.2 2.4 0.7 1.3 1.5 2.4 0.5 9.6 0.6 0.3 1.1 2.5 0.0 0.5 0.4 0.4 0.0 0.0 0.6 0.8 1.5 0.5 0.4 2.6 14.9 1.3 2.2 2.8 0.4 0.3 0.2 1.0 0.3 2.3 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.3 0.3 0.2 0.1 0.0 0.6 0.0 11.5 14.7 12.5 13.4 11.0 12.4 13.7 13.3 13.1 11.1 12.7 16.3 1.7 0.0 0.0 16.0 1.0 8.3 0.5 0.7 4.6 1.7 2.9 5.5 1.4 1.5 0.4 0.0 0.0 0.2 1.7 0.4 0.0 0.5 588.7 0.8 1.2 2.2 0.0 0.0 1.2 0.0 0.4 2.0 0.0 1.1 0.0 1.5 0.7 0.0 0.9 3.3 1.5 0.4 0.0 0.3 16.8 349.4 7.8 1.4 5.4 0.0 0.7 7.4 0.0 4.5 14.1 0.2 0.1 3.8 0.0 0.7 0.5 0.1 0.4 0.1 6.6 1.7 1.8 22.9 2.6 1.6 6.1 0.1 2.2 0.4 0.4 0.4 C8A ENSG00000157131 "Complement C8 alpha chain" P07357 1 56854797-56918223 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 195 "liver: 635.7" "Cell type enriched" "Detected in some" 36 "Hepatocytes: 296.4" "Cancer enriched" "Detected in single" 279 "liver cancer: 85.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Hep G2: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 6400000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (3.73e-3)" "unprognostic (2.44e-1)" "unprognostic (1.28e-1)" "unprognostic (6.40e-2)" "unprognostic (9.82e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.1 635.7 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.0 5.3 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 296.4 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 C8B ENSG00000021852 "Complement C8 beta chain" P07358 1 56929207-56966140 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 156 "liver: 840.0" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 295.1" "Cancer enriched" "Detected in some" 181 "liver cancer: 107.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 22 "basophil: 2.1" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.1" "Cell line enriched" "Detected in single" 4 "Hep G2: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023694 Supported "Secreted to blood" NA NA 6700000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA023694: AB_1847128" "unprognostic (6.65e-2)" "prognostic favorable (9.31e-5)" "unprognostic (2.37e-1)" "unprognostic (2.37e-1)" "unprognostic (1.29e-2)" "unprognostic (6.57e-2)" "unprognostic (5.12e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 840.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.2 1.0 0.0 0.1 0.0 5.3 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 7.1 295.1 0.1 0.0 0.1 0.0 0.0 7.6 0.0 11.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 C8G ENSG00000176919 "Complement C8 gamma chain" P07360 9 136945185-136946975 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "liver: 564.4" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 1134.7" "Cancer enriched" "Detected in all" 58 "liver cancer: 260.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "HMC-1: 41.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA046269 Approved "Secreted to blood" NA NA 2800000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA046269: AB_2679606" "unprognostic (5.00e-2)" "unprognostic (4.05e-3)" "prognostic unfavorable (2.99e-4)" "unprognostic (3.94e-1)" "unprognostic (4.53e-1)" "unprognostic (2.75e-2)" "unprognostic (1.71e-3)" "unprognostic (2.79e-1)" "unprognostic (1.88e-1)" "unprognostic (3.67e-1)" "unprognostic (2.96e-2)" "unprognostic (3.00e-1)" "unprognostic (5.02e-3)" "unprognostic (2.16e-1)" "unprognostic (7.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.05e-2)" 0.3 1.5 0.1 0.0 0.1 0.0 0.3 0.1 0.3 0.3 0.0 1.2 31.2 0.4 0.9 0.5 0.4 2.5 1.3 0.1 0.1 2.3 564.4 0.3 0.1 0.1 0.1 0.1 0.3 0.0 0.6 0.0 0.2 0.4 0.3 0.0 0.4 0.1 3.1 0.3 17.8 0.0 0.1 2.1 1.3 2.3 0.1 0.2 0.7 0.0 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.4 0.0 0.0 41.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 1.0 0.0 0.0 0.3 2.3 0.4 0.2 0.4 0.0 0.0 0.4 0.9 0.7 28.6 0.3 0.0 2.1 0.4 1.1 25.0 0.0 0.2 0.9 0.1 0.1 0.7 1.8 8.0 0.2 0.8 1.0 0.1 0.0 0.3 8.9 1.2 17.5 1134.7 0.3 0.0 0.2 5.0 0.0 25.3 0.2 1.5 0.0 0.2 0.0 0.0 0.0 1.1 4.1 0.5 0.1 0.5 4.7 0.7 0.0 0.4 122.3 6.7 0.1 0.5 0.0 0.3 0.3 0.7 0.6 0.5 0.4 3.4 1.8 0.2 2.0 0.2 C9 ENSG00000113600 "Complement C9" P02748 5 39284140-39424868 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 288 "liver: 1397.0" "Cell type enriched" "Detected in some" 37 "Hepatocytes: 1962.3" "Cancer enriched" "Detected in single" 244 "liver cancer: 90.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "JURKAT: 9.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002151, HPA029577" Uncertain "Secreted to blood" NA NA 69600000000 64000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB002151: AB_563670, HPA029577: AB_10603779" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (1.50e-1)" "unprognostic (2.01e-1)" "unprognostic (6.58e-2)" "unprognostic (1.30e-1)" "unprognostic (2.91e-1)" "unprognostic (5.49e-3)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (2.19e-2)" "unprognostic (9.43e-5)" "unprognostic (1.36e-1)" "unprognostic (1.80e-1)" "unprognostic (2.04e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1397.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 20.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.8 2.0 0.0 18.7 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 42.5 1962.3 1.2 0.0 0.1 0.2 0.0 52.6 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.4 0.1 3.7 1.7 0.0 0.0 0.3 3.0 0.0 0.0 0.1 CA10 "CA-RPX, CARPX, HUCEP-15" ENSG00000154975 "Carbonic anhydrase 10" Q9NS85 17 51630313-52160017 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 54.9;cervix: 21.8;retina: 44.5" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 1607.5" "Cancer enriched" "Detected in some" 4 "glioma: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 1.2;RT4: 2.1;SCLC-21H: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054825, HPA057837" Supported Approved Vesicles "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA054825: AB_2682617, HPA057837: AB_2683542" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" "unprognostic (3.43e-1)" "unprognostic (8.22e-2)" "unprognostic (4.43e-3)" "unprognostic (1.02e-3)" "unprognostic (1.01e-1)" "unprognostic (5.91e-2)" "unprognostic (1.46e-1)" "unprognostic (7.21e-3)" "unprognostic (9.18e-5)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" 0.0 3.2 22.9 0.0 21.0 0.0 0.0 54.9 27.2 21.8 7.9 0.4 0.3 0.2 0.0 0.0 0.4 0.1 0.0 23.0 20.6 7.2 0.0 0.0 0.0 33.4 19.3 1.9 0.2 0.0 3.9 1.0 33.4 0.0 0.1 44.5 1.2 0.0 0.0 0.0 0.5 0.1 19.5 0.0 0.1 10.2 30.6 0.0 0.0 0.0 0.0 0.1 0.1 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.2 2.1 6.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 21.0 54.9 27.2 23.0 20.6 33.4 19.3 33.4 19.5 30.6 17.6 0.0 0.0 0.0 8.8 0.2 0.0 0.0 0.0 0.0 211.9 0.0 0.0 0.4 0.0 0.0 3.7 4.2 0.0 0.1 0.0 15.6 0.0 134.5 0.0 0.0 0.3 0.0 0.0 343.6 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.0 17.0 0.0 0.0 0.0 0.2 84.4 1.2 0.1 0.0 14.0 0.0 5.1 0.0 1607.5 4.2 0.0 0.0 0.7 0.1 0.2 0.0 0.2 0.0 11.9 0.0 0.1 0.0 1.5 1.3 0.0 0.0 0.1 2.2 0.0 0.0 0.1 CA11 "CARP2, CARPX1" ENSG00000063180 "Carbonic anhydrase 11" O75493 19 48637946-48646187 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 330.0;choroid plexus: 146.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 46.1;hTERT-RPE1: 47.1;SCLC-21H: 32.6;U-266/84: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041778 Approved Vesicles,Microtubules "Secreted in brain" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Microtubules" "HPA041778: AB_10794525" "unprognostic (1.39e-1)" "prognostic favorable (4.33e-4)" "unprognostic (2.59e-3)" "unprognostic (5.72e-2)" "unprognostic (1.54e-1)" "unprognostic (9.80e-3)" "unprognostic (6.02e-2)" "prognostic favorable (2.11e-5)" "unprognostic (3.79e-2)" "unprognostic (2.98e-1)" "prognostic favorable (8.60e-5)" "unprognostic (4.88e-2)" "unprognostic (8.64e-3)" "unprognostic (1.21e-1)" "unprognostic (7.15e-2)" "unprognostic (4.09e-3)" "unprognostic (1.75e-1)" 13.1 17.3 240.8 3.2 256.9 1.6 8.5 215.4 330.0 15.9 146.2 19.4 8.4 33.0 28.2 8.0 21.4 5.5 10.7 266.6 167.0 14.7 1.7 5.8 5.0 170.3 169.2 48.8 5.9 58.0 37.2 1.1 172.2 14.0 2.5 30.0 8.9 13.5 9.2 14.3 9.3 18.2 163.8 6.1 13.0 6.4 180.5 6.6 12.1 7.4 5.3 9.2 12.2 231.9 2.0 12.7 22.9 46.1 3.1 1.2 0.6 1.5 14.9 1.5 3.3 3.1 15.7 7.5 1.7 1.7 4.2 4.9 9.4 4.6 1.3 1.6 13.5 3.3 7.2 0.2 3.0 0.3 9.8 5.4 9.2 1.4 2.0 47.1 1.8 19.8 6.1 20.5 0.7 5.0 4.1 1.4 9.9 7.5 4.7 2.6 0.9 16.1 10.1 0.4 32.6 18.2 1.7 1.6 2.7 6.1 6.3 0.8 0.2 3.9 14.2 0.1 0.4 18.9 33.9 1.3 5.7 4.3 2.0 0.0 0.4 0.0 1.5 0.5 1.5 1.0 1.2 1.2 0.7 1.3 1.5 1.3 0.0 1.3 0.0 1.9 1.5 0.7 240.8 256.9 215.4 330.0 266.6 167.0 170.3 169.2 172.2 163.8 180.5 231.9 5.1 3.2 8.1 11.1 9.3 7.1 9.1 13.2 12.5 81.0 15.5 12.1 5.4 21.5 9.6 31.3 16.7 0.7 9.8 3.9 25.4 11.5 15.0 6.7 6.3 6.7 13.1 3.6 47.0 10.0 0.4 11.6 5.6 7.9 6.3 3.1 8.9 47.5 6.0 28.6 18.1 6.4 16.2 20.4 26.4 7.9 22.1 6.8 8.8 5.6 5.6 50.4 12.3 7.1 6.8 3.4 2.9 26.7 4.3 4.3 20.7 38.7 7.5 30.8 6.6 4.2 8.9 1.3 4.9 5.9 10.9 0.4 6.9 8.7 5.2 6.4 CA6 ENSG00000131686 "Carbonic anhydrase 6" P23280 1 8945867-8975092 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 295 "salivary gland: 9393.1" "Group enriched" "Detected in some" 44 "Breast glandular cells: 77.9;Ionocytes: 99.7;Melanocytes: 179.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 5.6;naive CD8 T-cell: 16.4" "Lineage enriched" "Detected in many" 11 "T-cells: 16.4" "Cell line enhanced" "Detected in some" "Daudi: 1.7;U-2197: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028550, HPA028692" Enhanced "Secreted to digestive system" NA NA 24000000 "Cluster 32: T-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA028550: AB_10600105, HPA028692: AB_10601883" "unprognostic (2.54e-5)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" "unprognostic (2.90e-1)" "unprognostic (9.28e-2)" "unprognostic (2.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (5.93e-2)" "unprognostic (4.41e-2)" "unprognostic (4.29e-5)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-1)" 0.4 0.4 0.3 0.7 0.6 2.0 20.8 0.9 0.7 0.0 0.5 0.1 0.3 0.2 2.3 0.2 0.1 0.2 1.5 0.4 0.3 0.1 0.1 0.3 1.3 0.9 0.4 1.9 6.3 0.0 0.1 0.9 0.7 0.2 0.2 0.7 9393.1 0.0 0.4 31.8 0.5 0.0 0.1 1.2 0.4 0.3 0.7 1.2 0.3 0.0 1.0 0.1 0.0 1.8 0.2 0.0 0.2 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.3 0.4 1.7 0.1 0.1 0.4 0.3 0.1 0.0 0.2 0.2 0.2 0.2 0.6 0.2 0.0 0.5 0.5 0.0 0.1 0.2 0.0 0.2 0.2 0.3 0.2 0.4 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.3 0.1 0.0 0.0 0.3 0.2 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.6 0.3 1.3 0.2 0.4 0.1 0.4 0.1 0.4 0.4 1.4 0.3 0.2 0.3 0.2 0.3 0.3 0.7 2.7 0.0 0.5 5.6 16.4 1.3 0.4 0.2 0.3 0.3 1.6 0.3 0.6 0.9 0.7 0.4 0.3 0.9 0.4 0.7 0.1 0.7 1.8 0.2 0.0 0.0 0.0 0.1 0.1 0.1 1.4 0.0 0.0 77.9 2.7 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 99.7 0.0 1.3 0.2 0.0 0.2 179.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.6 0.5 0.0 0.0 CA9 "CAIX, MN" ENSG00000107159 "Carbonic anhydrase 9" Q16790 9 35673918-35681159 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "stomach 1: 289.3" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 275.3;Cholangiocytes: 62.9;Early spermatids: 205.8;Gastric mucus-secreting cells: 259.5" "Cancer enhanced" "Detected in many" "renal cancer: 85.9" "Region enriched" "Detected in single" 9 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "A-431: 189.3;HDLM-2: 98.1;hTERT-RPE1: 113.1;U-87 MG: 374.4" "Region enhanced" "Detected in many" "cerebellum: 12.3" "Low region specificity" "Detected in all" "CAB005100, CAB017107, HPA055207" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB005100: AB_2066539, CAB017107: , HPA055207: AB_2682738" "unprognostic (8.01e-3)" "unprognostic (1.34e-2)" "unprognostic (2.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (1.47e-2)" "unprognostic (3.90e-2)" "unprognostic (1.29e-1)" "unprognostic (6.24e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.22e-7)" "unprognostic (7.29e-2)" "prognostic favorable (9.50e-4)" "unprognostic (2.97e-3)" "unprognostic (8.67e-2)" 3.8 0.4 0.0 0.2 0.0 0.0 0.1 5.6 0.6 0.5 0.0 0.6 14.5 0.2 0.1 0.8 0.4 24.4 2.0 0.2 0.1 0.2 1.3 0.2 0.0 0.0 0.1 0.7 6.6 0.0 0.5 0.0 0.2 0.5 0.0 1.0 0.1 0.1 0.1 8.2 13.6 0.1 0.0 0.0 289.3 5.5 0.5 0.0 0.0 0.0 0.0 0.7 0.7 0.0 189.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.3 2.5 0.0 0.1 0.0 0.1 0.0 0.5 5.7 0.0 0.9 1.5 98.1 0.0 0.0 0.7 0.4 0.0 0.0 0.2 0.4 0.0 0.0 0.3 113.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.3 0.2 0.5 0.0 0.0 10.6 0.0 0.6 1.6 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 18.9 0.4 0.0 4.7 0.0 0.4 0.1 374.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.6 0.2 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 4.5 0.7 275.3 0.0 0.4 0.1 0.0 0.4 62.9 28.1 0.0 0.0 0.0 0.0 0.1 0.0 49.1 205.8 0.0 0.1 0.2 0.0 0.0 0.1 50.9 0.6 1.2 259.5 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.6 4.0 18.3 0.0 0.0 19.6 1.5 0.1 0.0 0.0 0.6 1.3 0.0 0.0 0.0 26.6 0.0 0.7 0.3 0.8 0.7 0.1 5.5 0.0 0.0 0.0 1.5 0.9 4.0 0.0 3.1 0.3 0.1 0.7 5.3 0.4 CABLES1 "FLJ35924, HsT2563" ENSG00000134508 "Cdk5 and Abl enzyme substrate 1" Q8TDN4 18 23134564-23260467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.2" "Cell type enhanced" "Detected in many" "Astrocytes: 258.2;Glandular and luminal cells: 54.3;Oligodendrocyte precursor cells: 163.3" "Cancer enriched" "Detected in all" 5 "melanoma: 38.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "SK-MEL-30: 154.3;U-266/70: 216.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073649 Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear bodies" "HPA073649: AB_2732233" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "unprognostic (1.97e-1)" "unprognostic (4.24e-3)" "unprognostic (1.56e-1)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.10e-3)" "unprognostic (1.42e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "prognostic favorable (4.71e-6)" "unprognostic (1.00e-1)" "unprognostic (1.60e-1)" "unprognostic (4.80e-2)" "unprognostic (7.81e-2)" 17.1 3.3 63.9 2.1 67.9 2.6 13.8 36.8 54.8 6.9 17.1 5.2 7.5 9.4 3.2 6.9 10.9 5.2 4.6 44.9 53.5 13.1 9.9 21.5 2.8 39.6 59.0 3.7 3.0 21.9 4.0 10.4 40.8 3.7 5.1 8.0 22.3 4.5 1.5 17.2 6.7 6.6 31.2 3.7 14.5 3.5 70.2 4.9 15.0 1.8 2.3 5.4 7.8 33.3 13.1 14.4 11.8 0.9 7.1 0.3 20.4 3.1 17.3 4.2 2.5 9.5 23.0 0.7 13.3 14.9 42.3 11.4 9.0 2.3 3.2 0.3 19.4 1.0 38.7 37.1 6.2 2.5 1.0 4.2 2.1 5.3 6.1 26.8 47.1 2.3 0.5 16.2 11.7 30.2 0.1 8.8 7.5 64.5 46.6 3.1 42.2 50.6 21.2 31.5 11.2 8.2 26.1 32.5 154.3 8.3 52.4 7.2 79.3 47.9 0.5 1.6 3.8 216.0 88.9 27.4 0.2 19.2 16.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 0.0 63.9 67.9 36.8 54.8 44.9 53.5 39.6 59.0 40.8 31.2 70.2 33.3 2.9 22.4 27.4 258.2 3.8 5.1 2.0 1.4 5.2 4.1 9.2 6.7 1.4 7.2 2.3 3.7 29.2 0.9 1.3 8.5 1.9 1.1 2.0 11.6 4.4 6.0 3.5 1.3 19.2 2.3 1.1 4.1 10.2 54.3 0.0 14.8 25.0 9.3 16.6 0.0 22.2 4.6 0.0 3.5 3.1 3.5 0.0 4.7 28.4 41.2 0.0 1.4 0.0 163.3 1.4 2.4 5.2 6.0 3.6 0.6 6.7 14.3 1.8 18.7 0.0 5.0 2.1 0.2 3.2 1.6 6.7 0.3 1.4 0.5 2.1 2.2 CABP1 ENSG00000157782 "Calcium binding protein 1" Q9NZU7 12 120640552-120667324 "Predicted intracellular proteins" "Sensory transduction, Vision" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 312.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 126.7;Excitatory neurons: 296.9;Horizontal cells: 323.0" "Cancer enhanced" "Detected in some" "renal cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.8;NTERA-2: 6.8;RT4: 3.9;SCLC-21H: 3.2;U-87 MG: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051438 Uncertain "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA051438: AB_2681486" "unprognostic (2.57e-1)" "unprognostic (4.79e-2)" "unprognostic (1.92e-4)" "unprognostic (1.16e-1)" "unprognostic (4.13e-3)" "unprognostic (6.28e-2)" "unprognostic (4.61e-2)" "unprognostic (2.85e-1)" "unprognostic (8.12e-3)" "unprognostic (7.59e-2)" "unprognostic (1.04e-2)" "unprognostic (6.60e-2)" "unprognostic (7.73e-3)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (3.61e-2)" "unprognostic (2.85e-1)" 11.6 1.7 138.0 0.6 169.4 0.0 5.1 99.4 312.4 3.0 74.7 2.9 0.8 2.8 3.2 1.4 3.1 1.0 12.7 151.5 86.8 24.3 0.2 0.6 0.3 96.4 88.5 1.2 1.5 7.4 5.5 1.2 97.3 3.6 1.5 25.7 0.4 3.7 2.8 0.9 2.3 2.3 87.0 1.2 2.9 1.4 84.9 0.2 1.3 5.5 0.2 6.1 2.9 207.3 0.1 0.5 2.8 0.9 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.2 0.0 0.0 0.5 0.0 1.2 0.2 2.5 0.0 0.1 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.1 0.1 1.2 0.0 0.0 0.0 0.3 0.3 0.0 6.8 2.2 0.4 1.7 0.0 0.0 2.7 3.9 3.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 8.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 138.0 169.4 99.4 312.4 151.5 86.8 96.4 88.5 97.3 87.0 84.9 207.3 43.4 0.0 0.0 9.1 0.0 0.1 0.2 0.1 0.0 126.7 0.4 0.3 2.6 0.0 0.0 1.8 0.0 0.1 0.0 0.5 31.3 0.1 2.1 0.0 0.1 8.9 0.0 0.0 296.9 0.0 0.4 2.8 3.1 0.1 0.0 0.0 0.0 0.0 0.3 323.0 44.2 0.5 0.0 0.0 2.0 3.6 0.3 0.3 0.0 9.4 0.0 9.9 0.0 22.6 8.5 0.0 0.0 2.2 0.0 0.3 0.0 3.7 0.0 10.9 19.7 0.5 12.6 0.4 1.8 0.0 0.3 0.3 0.2 0.1 0.0 0.2 CACNA2D1 "CACNA2, CACNL2A, LINC01112, lncRNA-N3, MHS3" ENSG00000153956 "Calcium voltage-gated channel auxiliary subunit alpha2delta 1" P54289 7 81946444-82443777 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 78.7;tongue: 98.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 543.1;Inhibitory neurons: 383.3;Oligodendrocyte precursor cells: 357.9;Oligodendrocytes: 662.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 127.4;HUVEC TERT2: 54.9;SH-SY5Y: 62.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008213, HPA008621" Enhanced "Intracellular and membrane" NA NA 390000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA008213: AB_1233654, HPA008621: AB_1845863" "unprognostic (5.07e-3)" "unprognostic (2.21e-1)" "unprognostic (4.27e-3)" "unprognostic (2.92e-2)" "unprognostic (2.27e-1)" "unprognostic (1.39e-1)" "unprognostic (1.70e-1)" "unprognostic (3.22e-1)" "unprognostic (3.76e-1)" "unprognostic (2.05e-1)" "unprognostic (6.24e-3)" "unprognostic (2.23e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (4.28e-3)" "unprognostic (2.13e-1)" "unprognostic (9.18e-2)" "unprognostic (1.03e-4)" 11.6 14.5 9.8 4.3 11.9 0.0 4.1 1.2 15.4 5.3 0.0 13.0 5.1 7.4 2.4 5.3 3.9 6.4 31.3 18.8 13.3 8.4 1.3 3.4 1.9 4.6 26.0 7.9 1.5 1.2 6.3 4.2 9.5 13.7 5.1 8.3 2.6 6.4 78.7 4.7 3.4 12.2 8.1 4.4 5.6 3.7 34.2 3.9 18.9 98.5 3.1 7.1 3.4 12.8 0.0 12.7 10.6 0.0 18.2 22.9 0.0 23.4 15.0 11.4 11.1 0.0 3.5 0.0 0.0 20.4 14.1 0.0 11.2 0.0 14.8 0.0 15.0 0.7 14.4 0.0 11.9 5.3 0.0 13.6 0.1 39.6 0.1 127.4 54.9 0.0 0.0 0.2 25.7 0.1 0.0 0.0 12.6 0.0 5.0 2.3 2.1 0.0 0.9 0.9 21.1 62.3 4.6 0.1 0.0 11.1 0.1 0.0 39.6 20.1 15.0 20.1 0.0 0.1 0.0 0.0 16.9 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 11.9 1.2 15.4 18.8 13.3 4.6 26.0 9.5 8.1 34.2 12.8 6.3 0.0 1.7 137.1 0.0 5.7 4.5 0.1 8.0 47.7 6.6 3.9 88.0 0.0 1.3 7.3 18.8 0.1 0.1 0.0 0.0 0.0 64.2 0.5 20.7 6.8 38.8 0.0 543.1 0.0 0.0 20.6 14.3 0.4 25.3 29.9 1.4 0.4 0.2 25.2 383.3 2.6 16.2 0.0 2.9 42.4 10.2 0.4 1.8 87.1 0.6 5.6 0.0 357.9 662.8 0.8 0.0 6.0 0.2 11.2 0.0 9.5 0.7 6.1 6.6 17.6 21.5 1.5 1.9 1.9 6.5 0.1 0.4 32.7 0.2 1.4 CACNA2D2 KIAA0558 ENSG00000007402 "Calcium voltage-gated channel auxiliary subunit alpha2delta 2" Q9NY47 3 50362613-50504244 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 49.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Alveolar cells type 2: 182.3;Inhibitory neurons: 36.0" "Cancer enhanced" "Detected in many" "testis cancer: 20.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 192.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034771, HPA071829" Enhanced Approved Vesicles NA NA 9700000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA034771: AB_10603555, HPA071829: AB_2686454" "unprognostic (2.06e-1)" "unprognostic (2.37e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (7.62e-5)" "unprognostic (6.59e-2)" "unprognostic (6.37e-2)" "unprognostic (6.91e-2)" "unprognostic (6.57e-3)" "unprognostic (4.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.21e-4)" "unprognostic (2.71e-2)" "unprognostic (1.57e-4)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (3.55e-1)" "unprognostic (4.22e-2)" 1.0 0.6 4.7 1.3 5.2 1.2 1.2 9.9 6.9 1.4 0.3 1.6 1.2 1.6 0.9 0.6 1.1 0.7 8.4 0.7 13.9 2.3 0.3 49.1 1.2 8.3 8.4 2.1 4.3 2.5 7.1 1.8 14.0 3.0 1.9 8.6 1.3 1.1 1.8 2.6 1.6 1.2 4.8 1.4 4.1 6.5 11.4 1.0 2.2 1.5 0.5 0.5 0.7 2.1 0.0 0.1 3.0 6.6 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.6 0.0 0.6 0.2 24.8 0.0 0.1 0.1 1.8 0.2 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.4 0.0 1.1 0.1 0.2 7.9 0.2 0.5 0.2 0.0 0.7 0.0 0.0 18.6 192.7 0.6 0.4 0.0 5.5 1.5 0.0 0.0 0.1 1.8 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.9 0.7 0.9 0.7 0.0 0.5 1.2 0.7 0.0 0.9 0.0 0.1 1.2 0.4 4.7 5.2 9.9 6.9 0.7 13.9 8.3 8.4 14.0 4.8 11.4 2.1 0.4 76.9 182.3 4.2 0.4 1.5 0.4 0.0 1.8 21.5 2.5 1.7 4.6 0.0 2.5 1.8 20.9 0.0 6.8 0.8 0.0 0.2 0.7 0.1 0.4 0.6 1.2 2.7 7.8 0.0 0.0 1.5 3.1 0.2 20.3 0.3 0.4 0.0 0.1 0.0 36.0 11.0 0.0 0.0 0.4 4.0 0.3 0.4 0.0 1.9 0.1 4.3 15.5 6.0 0.9 0.4 0.3 1.9 2.9 0.7 0.2 0.7 2.2 9.8 13.1 2.4 2.4 2.6 11.2 0.2 0.6 0.3 2.9 3.4 0.6 0.3 CACNA2D4 ENSG00000151062 "Calcium voltage-gated channel auxiliary subunit alpha2delta 4" Q7Z3S7 12 1791963-1918666 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 39 "retina: 20.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 56.3;Cone photoreceptor cells: 156.4;Early spermatids: 56.3;Late spermatids: 117.6;Rod photoreceptor cells: 98.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 2.9;monocytes: 4.4;T-cells: 4.2" "Cell line enhanced" "Detected in some" "Hep G2: 4.7;HL-60: 2.8;HMC-1: 14.0;NB-4: 6.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA031952 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 79: Retina - Phototransduction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA031952: AB_10600798" "unprognostic (5.04e-2)" "unprognostic (2.82e-2)" "unprognostic (5.32e-1)" "unprognostic (7.50e-2)" "unprognostic (1.15e-1)" "unprognostic (8.18e-4)" "unprognostic (1.10e-2)" "unprognostic (1.31e-1)" "unprognostic (2.08e-1)" "unprognostic (3.30e-3)" "unprognostic (1.24e-2)" "unprognostic (1.41e-1)" "unprognostic (1.62e-5)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (2.04e-1)" "unprognostic (2.13e-1)" 0.3 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.0 20.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.3 0.2 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 4.7 0.2 2.8 14.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 4.4 0.0 2.1 1.7 4.2 0.0 1.0 1.5 2.9 0.0 0.5 0.3 0.1 0.4 0.5 0.1 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 1.7 0.0 1.9 0.7 2.4 0.9 0.4 0.1 1.2 56.3 0.7 1.0 0.9 2.8 0.8 0.0 156.4 0.1 5.5 2.4 0.0 0.8 56.3 0.2 1.2 1.5 1.2 0.4 0.8 0.4 0.2 1.8 1.1 0.2 15.2 0.8 1.4 1.2 23.7 0.0 0.4 2.1 0.0 29.2 5.7 117.6 0.9 23.2 3.6 0.0 17.3 6.9 18.6 0.0 1.8 0.3 3.4 0.4 0.8 0.2 12.2 1.3 1.1 98.5 0.0 0.3 2.3 9.0 4.9 0.4 0.6 0.1 8.6 0.6 3.4 0.3 CADM3 "BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1" ENSG00000162706 "Cell adhesion molecule 3" Q8N126 1 159171609-159203313 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 151.6;placenta: 80.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 146.4;Excitatory neurons: 35.5;Fibroblasts: 39.5;Horizontal cells: 35.3;Inhibitory neurons: 40.5;Muller glia cells: 39.4" "Cancer enriched" "Detected in many" 4 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 65.0;HSkMC: 218.8;hTERT-HME1: 118.5;WM-115: 60.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002981, CAB025746" Enhanced Supported "Intracellular and membrane" NA NA 800000 "Cluster 6: Brain - Smell perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 33: Fibroblasts - ECM organization" "CAB025746: , HPA002981: AB_1078916" "unprognostic (1.74e-2)" "unprognostic (8.26e-2)" "unprognostic (1.34e-2)" "unprognostic (1.33e-2)" "unprognostic (9.32e-2)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (6.12e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (5.52e-2)" "unprognostic (2.59e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (5.75e-4)" 17.3 7.9 102.0 15.1 139.6 0.1 9.2 151.6 145.4 27.6 1.2 28.2 4.4 3.9 1.3 11.5 9.2 6.2 18.1 143.1 96.2 2.2 0.6 5.0 14.3 87.4 84.1 1.5 2.2 0.2 31.0 80.6 120.7 5.1 14.4 66.8 5.9 4.7 2.3 13.0 15.8 6.1 66.3 13.3 11.1 3.0 99.4 1.2 7.3 6.5 9.8 16.2 31.0 60.8 0.0 0.0 0.6 0.0 4.2 1.2 0.0 0.0 0.0 9.4 1.8 0.0 0.0 0.1 0.5 0.0 0.1 0.1 0.0 0.0 3.8 0.0 0.0 3.7 0.0 0.0 65.0 0.0 0.2 218.8 0.0 0.1 118.5 0.0 5.3 0.0 0.0 0.2 2.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.1 4.1 0.0 0.0 5.0 0.0 0.1 9.1 0.0 32.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 60.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.0 139.6 151.6 145.4 143.1 96.2 87.4 84.1 120.7 66.3 99.4 60.8 4.2 0.0 0.5 11.4 0.0 6.6 0.1 0.0 0.6 146.4 0.1 0.8 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.0 0.0 0.2 8.0 0.0 0.0 35.5 0.0 0.8 39.5 0.5 0.0 0.0 0.0 3.6 0.0 1.2 35.3 40.5 0.0 0.0 0.0 10.7 8.3 0.6 0.3 24.9 1.9 0.0 39.4 0.0 18.6 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.6 0.0 16.3 3.6 3.1 2.6 0.3 4.3 0.7 0.6 0.0 0.0 0.1 CALCA "CALC1, CGRP, CGRP-alpha" ENSG00000110680 "Calcitonin related polypeptide alpha" "P01258, P06881" 11 14966668-14972351 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, Transporters" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 178.3;thyroid gland: 154.2" "Cell type enriched" "Detected in some" 64 "Ionocytes: 2368.1" "Cancer enriched" "Detected in many" 7 "lung cancer: 64.7" "Region enhanced" "Detected in many" "pons: 34.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "pons and medulla: 57.9" "HPA059886, HPA064453" Enhanced Supported "Secreted to blood" NA NA 51500 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA059886: , HPA064453: " "unprognostic (1.97e-1)" "prognostic unfavorable (4.49e-5)" "unprognostic (5.99e-2)" "unprognostic (2.42e-1)" "unprognostic (1.17e-1)" "unprognostic (6.45e-2)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" "unprognostic (3.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.74e-2)" "unprognostic (2.53e-3)" "unprognostic (1.02e-2)" 0.7 0.2 0.6 1.5 0.6 0.0 0.2 0.6 0.5 0.2 0.0 0.6 0.0 0.2 0.0 0.1 0.3 0.2 1.1 0.3 0.8 46.4 37.5 2.4 0.1 20.9 7.0 0.1 0.4 178.3 0.8 0.0 34.4 2.5 0.1 0.0 0.1 0.0 0.5 0.0 0.1 1.5 1.5 3.0 0.2 0.2 0.6 0.3 154.2 0.0 0.0 4.3 0.4 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.5 0.3 0.8 20.9 7.0 34.4 1.5 0.6 10.4 0.1 0.0 0.0 0.0 0.2 0.3 0.4 35.4 0.0 0.0 0.0 0.1 0.4 0.0 0.3 36.8 0.0 0.0 0.0 0.0 5.9 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.3 0.0 0.0 0.7 4.4 0.3 0.0 0.0 0.0 2368.1 0.0 4.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.2 0.0 0.0 0.4 5.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 CALCB "CALC2, CGRP-II, FLJ30166" ENSG00000175868 "Calcitonin related polypeptide beta" P10092 11 14904997-15082342 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Hormone "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 18.9;thyroid gland: 20.7" "Group enriched" "Detected in some" 4 "Melanocytes: 5.4;Spermatogonia: 5.1" "Group enriched" "Detected in some" 5 "colorectal cancer: 1.2;endometrial cancer: 2.4;thyroid cancer: 0.9" "Group enriched" "Detected in many" 4 "hypothalamus: 6.8;medulla oblongata: 8.9;midbrain: 11.6;pons: 18.9;white matter: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 5.8;Karpas-707: 10.4;SH-SY5Y: 3.5;U-266/70: 16.0" "Region enriched" "Detected in some" 7 "pons and medulla: 9.6" "Group enriched" "Detected in many" 5 "amygdala: 30.4;basal ganglia: 74.3;hypothalamus: 50.1;midbrain: 33.9;pons: 41.7" HPA059886 Supported "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "HPA059886: " "unprognostic (7.84e-2)" "unprognostic (4.07e-1)" "unprognostic (3.92e-1)" "prognostic unfavorable (3.42e-5)" "unprognostic (2.02e-1)" "unprognostic (8.40e-2)" "unprognostic (1.75e-1)" "unprognostic (7.21e-2)" "unprognostic (2.07e-1)" "unprognostic (3.32e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-1)" "unprognostic (1.02e-2)" "unprognostic (2.33e-2)" "unprognostic (2.66e-1)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" 0.3 0.0 0.1 0.3 0.2 0.0 0.2 0.5 0.6 0.2 0.1 1.4 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.3 6.8 1.0 0.8 0.1 0.1 8.9 11.6 0.1 1.5 0.3 2.2 0.1 18.9 0.1 0.2 0.1 0.3 0.0 0.8 0.1 0.4 0.1 2.3 0.1 0.1 0.3 1.0 0.0 20.7 0.1 0.1 0.0 0.1 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.2 5.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 1.9 0.0 0.4 0.1 0.0 10.4 0.0 0.0 0.0 0.6 2.9 0.1 0.1 0.4 0.0 0.2 0.0 0.0 1.1 3.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 16.0 0.6 0.4 2.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.6 0.3 6.8 8.9 11.6 18.9 2.3 1.0 4.7 0.0 0.0 0.0 0.3 0.2 1.3 0.1 0.0 0.0 0.0 0.6 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.3 0.1 0.4 0.0 0.0 0.4 0.2 0.9 0.5 0.2 0.5 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.3 0.0 0.0 5.4 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.9 5.1 0.0 0.0 0.1 1.2 0.0 0.0 0.1 CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.7;lung: 76.8" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Endometrial stromal cells: 92.7;Endothelial cells: 248.7;Hepatic stellate cells: 259.2;Oligodendrocyte precursor cells: 293.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cell line enriched" "Detected in some" 4 "HUVEC TERT2: 173.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA008070: AB_1845912, HPA046515: AB_2679681" "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" 70.7 6.3 3.4 12.3 4.0 0.4 15.8 6.1 4.4 27.8 3.4 6.9 6.0 21.5 4.6 8.6 11.4 24.4 20.4 3.9 3.8 14.0 12.6 76.8 7.9 11.1 6.2 15.7 4.3 13.0 3.6 11.7 10.8 7.3 9.5 0.9 7.1 7.7 6.2 3.9 6.3 27.1 15.5 8.6 7.1 2.7 3.9 4.6 28.3 20.2 9.1 14.1 4.7 15.2 0.2 0.0 8.8 0.0 6.2 1.6 0.0 0.8 1.3 0.1 1.0 0.0 1.0 0.0 2.3 0.7 0.2 0.0 0.0 0.6 0.2 1.5 0.5 1.5 0.0 0.2 4.9 0.2 0.0 4.6 0.2 0.3 2.1 0.5 173.6 0.1 0.0 2.5 1.2 0.0 0.8 0.1 0.5 0.0 0.0 0.0 3.1 0.5 40.5 0.0 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.2 25.3 0.7 0.1 0.1 0.4 6.2 0.1 0.7 0.4 0.0 0.0 0.0 2.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 9.2 0.0 0.8 0.1 0.1 1.0 1.0 2.6 0.0 0.9 3.4 4.0 6.1 4.4 3.9 3.8 11.1 6.2 10.8 15.5 3.9 15.2 138.3 0.0 11.9 19.6 1.2 9.3 2.3 1.7 21.6 0.2 0.8 1.8 12.3 2.8 3.6 0.0 0.0 0.4 2.4 0.0 3.9 0.3 0.8 3.1 92.7 248.7 0.0 4.8 15.4 0.4 0.2 56.5 1.1 1.7 5.1 12.3 259.2 1.8 0.9 0.0 2.1 0.0 2.0 10.3 29.7 1.0 7.8 15.4 10.6 47.8 16.1 0.0 1.0 293.0 1.0 0.1 0.0 2.6 4.9 1.9 0.0 13.2 2.8 0.1 6.6 4.1 21.5 1.3 0.7 18.2 6.8 0.3 3.0 6.0 0.0 1.8 CALHM6 "C6orf187, dJ93H18.5, FAM26F, INAM, OTTHUMP00000017061, OTTHUMP00000017062, RP1-93H18.5" ENSG00000188820 "Calcium homeostasis modulator family member 6" Q5R3K3 6 116461370-116463771 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 136.6" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 724.6;non-classical monocyte: 861.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 28.0;Karpas-707: 45.1;RPMI-8226: 159.8;U-937: 59.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.14e-2)" "unprognostic (2.31e-2)" "unprognostic (6.46e-3)" "unprognostic (7.15e-3)" "unprognostic (9.53e-3)" "unprognostic (4.10e-2)" "unprognostic (2.69e-1)" "unprognostic (1.68e-1)" "unprognostic (8.19e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (9.31e-10)" "unprognostic (1.69e-1)" "unprognostic (2.12e-2)" "unprognostic (3.85e-3)" "unprognostic (9.25e-3)" 7.4 7.3 4.9 60.2 5.2 41.4 10.0 4.5 6.6 4.3 5.0 10.4 12.2 2.4 3.6 4.1 4.1 7.2 4.3 4.7 5.2 4.1 24.7 10.8 73.0 8.1 4.7 4.5 1.8 1.7 4.8 12.5 5.3 5.4 7.0 1.1 5.7 3.0 1.6 1.9 20.9 11.8 5.6 136.6 7.9 8.2 5.3 14.0 2.4 2.6 23.1 11.4 3.0 5.4 6.4 0.0 0.6 0.4 0.5 2.0 11.7 0.2 1.3 2.0 1.3 0.0 1.0 0.2 3.5 1.5 0.0 0.0 0.3 0.2 4.2 0.7 0.4 28.0 0.0 0.0 2.8 0.1 0.1 2.2 0.0 0.2 0.2 0.5 0.7 0.0 0.0 45.1 5.5 0.0 2.7 4.8 3.6 0.0 0.0 2.4 0.0 159.8 2.2 0.3 2.7 0.1 14.9 0.1 11.7 1.6 0.2 7.3 0.1 0.0 0.2 0.1 0.9 11.4 0.2 0.0 0.3 59.7 3.9 22.0 205.7 50.1 16.6 724.6 16.6 231.8 23.0 15.5 193.8 308.9 28.9 15.2 115.8 27.4 861.9 86.5 2.7 175.6 4.9 5.2 4.5 6.6 4.7 5.2 8.1 4.7 5.3 5.6 5.3 5.4 0.6 0.0 1.7 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 1.7 2.7 0.0 0.0 0.6 0.0 0.2 0.3 0.8 0.0 0.0 0.0 10.0 9.0 0.7 0.0 0.1 0.0 1.4 0.0 0.0 138.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 10.3 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.2 1.2 1.8 0.0 0.0 CALR "cC1qR, CRT, FLJ26680, RO, SSA" ENSG00000179218 Calreticulin P27797 19 12938578-12944489 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1717.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001513, HPA002242, CAB019952, CAB079775" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 210000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "CAB001513: , CAB019952: AB_2069792, CAB079775: AB_303403, HPA002242: AB_1078384" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (8.46e-2)" "unprognostic (4.25e-2)" "unprognostic (9.44e-3)" "unprognostic (6.93e-2)" "unprognostic (2.47e-2)" "unprognostic (4.60e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.07e-1)" "unprognostic (3.76e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.37e-1)" "unprognostic (1.96e-1)" "unprognostic (1.37e-1)" "unprognostic (5.27e-2)" 295.5 257.6 201.7 352.9 213.4 554.9 218.9 238.0 213.5 256.3 324.0 304.6 287.3 275.8 647.7 338.2 266.7 164.1 303.2 203.5 239.7 296.9 782.3 308.9 230.0 260.4 230.1 272.2 319.7 292.2 284.5 403.3 254.5 277.9 336.7 96.2 299.3 247.2 119.8 189.3 277.2 349.7 237.7 277.3 300.6 165.2 267.3 245.3 702.9 104.7 319.4 252.2 236.6 274.2 1681.4 673.6 832.5 1984.9 1110.8 861.5 724.6 2075.3 1160.8 839.6 1280.4 1044.2 1353.5 1087.2 1960.0 2528.4 1064.5 672.1 906.1 1476.5 800.7 730.0 588.1 894.3 689.0 1619.6 2667.5 3638.5 1171.8 946.8 638.7 1222.3 957.7 1472.5 1507.8 743.1 814.5 536.3 911.7 1222.3 1040.0 2511.9 808.7 952.0 970.1 777.0 770.8 1329.9 1138.3 846.9 312.4 668.4 1438.7 769.8 472.6 789.9 1014.4 1558.9 1460.6 1113.2 666.2 1533.6 938.3 644.3 569.7 985.8 1567.6 1616.3 1258.1 67.5 72.8 39.7 172.8 147.8 119.3 90.0 99.7 130.0 76.3 77.5 73.0 134.4 23.8 103.1 122.7 215.6 83.4 75.8 201.7 213.4 238.0 213.5 203.5 239.7 260.4 230.1 254.5 237.7 267.3 274.2 385.2 147.4 160.7 34.6 385.7 261.7 336.3 217.3 221.4 76.8 214.9 140.8 43.7 163.0 175.4 222.5 127.2 652.9 515.5 524.4 64.6 582.7 27.8 206.3 364.2 305.6 353.6 266.1 14.2 285.5 1717.5 422.5 289.5 348.2 207.4 341.6 312.7 612.4 789.3 35.3 23.8 595.1 93.6 208.8 433.2 30.6 318.7 378.4 213.5 31.9 229.9 316.5 360.5 28.6 31.1 410.2 462.8 311.1 1059.6 426.1 377.8 182.8 147.5 167.7 203.8 224.2 328.9 276.1 306.6 245.5 213.5 964.4 345.8 399.4 471.4 329.6 CALR3 "CRT2, CT93, FLJ25355, MGC26577" ENSG00000269058 "Calreticulin 3" Q96L12 19 16479061-16496167 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" Chaperone "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 72 "testis: 64.9" "Group enriched" "Detected in some" 7 "Early spermatids: 51.0;Late spermatids: 13.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025749, HPA043355, HPA048460" Enhanced "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "CAB025749: , HPA043355: AB_2678442, HPA048460: AB_2680403" "unprognostic (1.19e-1)" "unprognostic (3.84e-1)" "unprognostic (7.17e-2)" "unprognostic (4.34e-1)" "unprognostic (2.32e-1)" "unprognostic (2.95e-1)" "unprognostic (1.30e-2)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (1.18e-2)" "unprognostic (6.69e-7)" "unprognostic (1.60e-1)" "unprognostic (2.78e-1)" "unprognostic (6.28e-3)" "unprognostic (6.34e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 64.9 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.0 0.3 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 13.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CALU ENSG00000128595 Calumenin O43852 7 128739292-128773400 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 504.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 2467.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006018 Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 21000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA006018: AB_1845934" "unprognostic (7.22e-3)" "unprognostic (1.16e-3)" "unprognostic (3.16e-1)" "unprognostic (8.86e-2)" "unprognostic (1.27e-1)" "unprognostic (9.52e-3)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.05e-3)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (2.75e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.30e-11)" "unprognostic (3.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.60e-5)" 115.8 56.6 20.6 137.9 22.7 22.8 66.2 22.8 28.5 133.5 54.7 97.5 37.6 113.6 61.1 60.4 57.1 92.7 236.9 24.5 23.5 45.1 74.2 68.5 38.8 24.1 22.2 54.8 52.6 85.0 28.8 211.8 24.2 113.0 81.3 19.6 67.7 150.1 82.1 29.9 40.0 328.4 22.3 47.5 62.5 39.8 33.2 31.0 77.1 117.1 45.2 160.1 48.2 26.6 257.8 207.4 486.6 152.7 1348.5 1229.5 270.9 1821.7 1378.1 577.5 770.7 238.6 388.3 100.0 351.5 2467.8 850.4 144.9 258.2 318.2 826.5 80.6 138.2 136.6 283.7 295.0 657.1 187.2 254.3 930.5 223.6 868.3 370.6 904.4 537.3 116.4 237.9 172.8 1131.8 141.0 130.2 95.5 305.2 247.0 197.3 122.9 333.3 164.5 243.5 132.7 44.3 238.2 595.4 481.5 753.1 932.2 106.2 145.6 799.8 1706.6 234.2 1350.8 754.6 306.8 385.7 224.8 1478.6 223.6 1857.2 21.7 38.8 23.5 28.3 41.4 27.9 23.7 19.5 22.0 33.4 16.6 17.1 20.0 4.5 26.2 35.7 32.9 23.4 31.2 20.6 22.7 22.8 28.5 24.5 23.5 24.1 22.2 24.2 22.3 33.2 26.6 67.3 22.4 38.5 25.5 29.9 81.3 68.1 82.0 31.3 28.2 51.7 42.7 247.0 25.8 62.7 25.8 18.8 116.8 25.0 14.4 17.6 69.5 11.4 37.5 186.3 104.0 19.7 42.3 37.7 60.5 504.7 198.8 37.2 72.8 59.6 62.6 113.2 54.2 136.9 28.6 47.0 55.9 22.4 58.9 70.7 9.3 100.3 44.6 120.9 27.2 26.3 32.4 21.6 31.2 32.2 71.5 11.4 118.8 140.9 110.6 12.6 17.7 57.2 12.8 59.2 64.9 162.8 27.1 41.9 30.9 76.9 243.0 30.9 69.7 26.1 90.5 CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113451032-113761927 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 159.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 272.9;Excitatory neurons: 182.9;Inhibitory neurons: 200.0;Microglial cells: 187.4;Oligodendrocyte precursor cells: 203.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 272.6" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 240000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions, Cytosol" "HPA026281: AB_1845944, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (2.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.13e-1)" "unprognostic (7.49e-2)" "unprognostic (2.19e-1)" "unprognostic (5.09e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "unprognostic (7.81e-2)" "unprognostic (7.91e-3)" "unprognostic (2.62e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-2)" "unprognostic (1.87e-1)" "unprognostic (1.90e-2)" 28.6 25.6 52.7 26.6 45.1 5.7 21.0 45.8 52.0 18.9 1.6 36.4 28.8 23.5 9.8 29.7 18.8 30.7 159.3 60.2 23.9 19.3 37.3 22.9 35.2 11.8 33.9 25.4 15.2 56.5 9.1 19.8 12.6 32.2 39.1 79.2 13.4 41.7 105.1 15.8 34.1 24.9 21.0 18.4 37.1 19.8 46.7 16.3 23.7 60.0 31.4 27.4 19.7 22.9 4.8 62.5 67.5 22.8 144.0 272.6 24.0 145.4 96.3 56.0 48.0 42.3 17.6 91.2 20.7 102.3 70.7 2.1 42.6 22.8 56.6 35.1 10.8 0.0 22.0 49.2 73.0 0.1 0.2 176.3 30.5 43.5 107.1 88.5 50.6 11.3 3.6 39.4 106.8 17.1 9.3 3.6 9.8 60.3 22.8 17.9 79.0 0.4 57.3 42.7 18.2 18.3 20.0 29.3 19.5 55.9 0.6 23.7 30.7 146.9 34.8 63.6 29.1 30.4 16.5 76.7 75.7 5.5 70.8 0.0 12.7 0.0 6.7 7.0 12.7 11.2 6.6 7.5 15.7 22.6 7.4 6.5 0.9 9.7 2.5 0.1 13.2 7.7 52.7 45.1 45.8 52.0 60.2 23.9 11.8 33.9 12.6 21.0 46.7 22.9 43.7 41.7 37.6 128.3 55.1 18.4 16.6 8.3 22.8 83.3 14.0 17.1 272.9 62.9 24.7 29.5 87.6 0.5 19.0 70.9 5.9 8.4 3.2 18.2 35.2 27.2 103.8 3.6 182.9 20.1 0.4 50.1 71.9 47.0 10.1 13.0 24.3 57.2 18.6 72.3 200.0 88.1 14.2 17.3 22.3 6.2 20.2 31.5 5.4 187.4 16.0 35.9 28.8 203.1 128.0 11.6 57.3 19.9 20.4 36.2 52.4 23.1 21.7 74.0 6.6 32.8 44.4 3.1 3.4 37.1 31.8 1.1 27.8 12.3 48.6 27.5 CAMP "CAP18, FALL-39, FALL39, LL37" ENSG00000164047 "Cathelicidin antimicrobial peptide" P49913 3 48223347-48225491 "Plasma proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "bone marrow: 2914.5" "Cell type enhanced" "Detected in some" "Early spermatids: 16.3;Fibroblasts: 6.9;Late spermatids: 17.4;Prostatic glandular cells: 9.4;Spermatocytes: 5.0;Spermatogonia: 7.2" "Cancer enriched" "Detected in many" 4 "testis cancer: 10.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "eosinophil: 84.4;neutrophil: 335.4" "Lineage enriched" "Detected in many" 12 "granulocytes: 335.4" "Cell line enhanced" "Detected in some" "Daudi: 27.3;hTCEpi: 19.0;U-698: 77.5" "Not detected" "Not detected" "CAB015949, CAB016522, HPA029874" Enhanced "Secreted to blood" NA NA 617000000 28000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "CAB015949: , CAB016522: , HPA029874: AB_10600859" "unprognostic (2.14e-2)" "prognostic favorable (5.73e-4)" "unprognostic (4.59e-2)" "unprognostic (2.62e-1)" "unprognostic (9.41e-2)" "unprognostic (4.57e-5)" "unprognostic (3.09e-1)" "unprognostic (5.71e-2)" "unprognostic (4.89e-2)" "unprognostic (7.65e-2)" "unprognostic (1.32e-1)" "unprognostic (8.08e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-1)" "unprognostic (1.71e-1)" "unprognostic (1.80e-2)" "unprognostic (1.03e-2)" 0.8 0.1 0.1 1.6 0.1 2914.5 0.5 0.1 0.5 0.6 0.1 0.3 0.0 0.6 339.9 0.4 0.1 0.3 1.4 0.1 0.1 0.4 3.9 7.4 6.8 0.2 0.1 0.2 0.1 0.1 0.5 2.4 0.2 0.5 0.1 0.0 15.2 0.6 0.2 3.7 1.7 0.1 0.1 23.2 0.4 1.9 0.1 10.7 5.7 0.2 2.9 0.4 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 27.3 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 19.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 1.0 1.4 0.1 0.0 3.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 77.5 0.0 3.4 0.1 37.9 5.5 84.4 0.0 9.8 0.0 2.3 0.0 0.0 7.7 2.4 0.0 0.0 335.4 2.6 28.1 4.7 0.0 86.9 0.1 0.1 0.1 0.5 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 4.2 0.0 0.9 0.8 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 16.3 0.9 0.3 0.2 0.0 2.1 0.0 0.2 0.0 6.9 0.5 1.4 0.0 0.0 0.4 0.0 3.2 0.0 0.0 0.0 0.0 1.3 1.1 17.4 0.9 3.6 1.8 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.8 9.4 0.0 0.1 0.7 0.0 0.0 0.0 0.1 5.0 7.2 0.0 0.0 0.0 1.0 0.0 0.4 0.6 CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991716-79009867 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 139.5;Intestinal goblet cells: 155.6;Syncytiotrophoblasts: 101.5;Undifferentiated cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 445.4;T-47d: 282.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced Supported "Golgi apparatus" NA Yes 3300000 "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.41e-4)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" 15.8 23.9 10.4 24.7 12.4 19.1 25.4 13.6 11.3 32.3 13.8 89.2 51.9 17.4 8.7 44.8 18.2 25.2 17.0 11.1 12.6 16.1 17.3 16.4 15.2 14.6 14.5 14.6 19.6 24.5 17.5 25.9 13.9 71.8 82.8 7.4 62.7 32.4 14.9 14.9 55.5 15.5 13.8 26.5 51.1 20.7 14.5 14.7 13.9 12.4 15.1 16.7 21.7 17.8 106.5 112.1 31.9 46.3 29.7 35.2 38.9 66.0 51.3 66.7 55.9 53.8 99.6 25.3 36.1 46.1 83.0 53.7 27.1 49.8 68.4 43.0 46.4 33.7 34.1 45.9 25.0 33.0 51.6 33.7 32.4 62.7 34.2 40.9 116.1 42.5 42.3 43.2 46.4 58.4 50.2 19.8 22.1 445.4 103.1 27.6 51.8 29.8 29.8 53.5 45.6 45.4 33.9 227.2 50.2 50.3 282.6 38.6 56.6 101.9 90.5 46.4 83.1 48.9 43.8 24.3 64.4 24.9 65.3 6.3 4.0 8.7 5.5 4.4 5.7 3.9 4.3 4.8 3.8 2.5 4.1 4.1 17.4 3.1 3.0 2.7 3.6 4.6 10.4 12.4 13.6 11.3 11.1 12.6 14.6 14.5 13.9 13.8 14.5 17.8 12.6 28.9 20.6 5.9 11.8 16.6 15.3 16.8 6.8 6.4 49.9 16.3 13.3 14.3 15.1 12.9 14.6 36.6 8.9 139.5 3.9 34.7 14.0 10.7 13.1 16.3 51.0 15.2 4.1 28.8 39.4 13.5 38.2 19.0 5.7 20.0 41.7 14.4 24.9 5.0 5.2 155.6 16.2 12.4 9.5 15.7 11.8 14.2 14.2 3.7 18.1 8.1 11.3 5.0 10.2 37.7 55.8 7.5 16.6 33.4 39.4 6.7 9.7 8.7 6.6 9.5 13.3 23.9 5.8 12.0 13.1 101.5 11.1 11.3 100.2 19.4 CANX "CNX, IP90, P90" ENSG00000127022 Calnexin P27824 5 179678628-179731641 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 817.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 528.3;SK-MEL-30: 790.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004738, HPA009433, HPA009696" Enhanced Enhanced "Endoplasmic reticulum" NA NA 13000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "CAB004738: AB_626784, HPA009433: AB_1078380, HPA009696: AB_1078379" "unprognostic (6.56e-2)" "unprognostic (9.34e-3)" "prognostic favorable (1.38e-4)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" "unprognostic (1.41e-2)" "unprognostic (4.66e-3)" "unprognostic (8.57e-2)" "unprognostic (4.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.17e-3)" "unprognostic (4.48e-2)" "unprognostic (2.28e-1)" "unprognostic (1.87e-1)" "unprognostic (7.12e-2)" "prognostic unfavorable (3.17e-4)" "unprognostic (2.15e-1)" 128.3 112.8 15.0 36.3 17.6 76.0 110.6 18.8 31.1 121.4 25.1 108.7 45.0 137.7 171.7 106.7 109.8 6.2 137.5 13.8 24.1 121.4 193.2 112.7 18.4 24.7 24.1 129.6 209.7 9.6 96.5 75.0 20.2 96.0 62.6 68.0 123.3 17.8 111.6 83.5 97.4 85.0 19.2 73.2 115.2 75.0 17.9 9.0 159.2 53.6 16.6 112.0 95.6 22.6 13.0 91.5 89.5 53.0 295.4 229.3 37.9 261.4 342.8 341.2 298.2 148.2 49.6 309.3 351.0 127.8 121.4 18.7 120.2 121.1 405.9 64.6 6.3 63.0 247.8 22.9 399.9 82.9 50.0 39.1 313.5 118.6 528.3 56.1 93.9 23.9 43.2 99.9 39.9 51.2 40.9 15.1 9.4 11.7 6.4 43.2 71.3 24.9 252.1 82.8 24.4 8.0 62.7 16.7 790.3 182.7 267.3 16.3 234.7 49.9 56.5 36.1 200.2 19.7 87.2 46.1 53.3 50.4 46.5 51.8 61.8 17.4 29.9 38.9 34.4 14.4 21.2 25.0 47.6 10.0 15.3 15.6 9.6 32.1 30.1 38.7 16.4 74.1 15.0 17.6 18.8 31.1 13.8 24.1 24.7 24.1 20.2 19.2 17.9 22.6 187.0 198.7 296.6 53.5 109.4 148.5 115.4 181.3 152.0 117.4 245.8 153.5 537.0 185.8 247.0 182.1 158.4 162.5 148.6 174.3 49.0 173.6 225.5 160.9 253.9 204.0 178.0 133.3 45.5 153.5 245.8 202.8 156.5 255.5 197.9 137.7 157.5 438.7 227.7 159.9 77.0 250.0 134.3 206.4 215.6 817.5 159.1 218.3 176.1 44.0 181.1 213.8 84.5 63.3 79.4 153.1 125.1 191.1 327.3 249.5 188.2 196.4 294.3 160.9 92.1 114.6 211.2 158.4 72.7 182.3 161.8 244.8 105.8 183.1 251.0 157.8 CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 276.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 516.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol NA NA 9100000 "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA005992: AB_1845924" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.33e-1)" "prognostic favorable (7.06e-8)" "unprognostic (5.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.98e-1)" 44.8 43.1 27.8 51.9 26.1 66.5 48.4 29.7 30.1 80.9 28.3 78.6 80.4 56.3 27.5 276.2 92.3 55.5 53.1 27.7 33.0 53.1 44.3 56.9 57.0 41.4 31.5 44.5 71.7 36.6 40.8 56.2 43.4 62.1 57.6 9.6 118.7 67.4 84.8 125.1 88.1 45.3 33.9 50.2 65.5 6.1 37.9 49.5 71.5 55.3 86.4 83.4 117.4 27.4 285.6 147.9 42.9 97.2 77.9 104.3 127.0 84.1 144.2 103.0 74.9 94.8 250.2 71.2 136.0 179.3 111.1 409.8 60.9 366.9 32.2 76.4 44.1 170.8 80.4 93.7 76.2 40.6 228.0 107.3 196.8 85.9 43.2 92.6 178.5 50.6 103.1 55.9 87.4 181.8 83.1 130.6 120.5 145.2 133.8 80.7 43.0 43.2 138.1 516.5 76.2 55.7 87.4 331.4 80.3 45.8 142.8 77.9 147.1 73.1 50.5 159.0 38.5 33.8 26.9 86.6 127.5 48.8 82.3 87.6 57.5 77.9 39.4 51.2 31.0 30.8 30.7 35.8 48.4 31.7 17.6 24.9 33.1 34.8 30.4 38.1 35.9 74.8 27.8 26.1 29.7 30.1 27.7 33.0 41.4 31.5 43.4 33.9 37.9 27.4 27.3 25.6 27.9 21.5 39.6 59.9 127.3 120.5 56.9 10.7 44.7 36.6 22.0 74.4 81.0 77.3 20.9 238.5 61.4 184.2 39.2 180.5 0.5 41.9 26.3 31.3 44.3 58.3 15.9 115.8 111.7 39.6 57.6 58.2 46.9 48.6 37.9 36.7 88.7 21.9 15.2 76.9 59.0 51.2 34.0 2.0 43.5 67.1 48.0 14.0 112.7 38.5 61.8 6.6 1.9 179.4 124.1 50.8 17.7 78.6 155.6 34.6 71.1 16.2 39.5 25.3 36.7 0.5 2.8 102.0 68.9 196.6 40.2 35.4 125.3 156.6 CAPNS1 "30K, CANP, CANPS, CAPN4, CDPS" ENSG00000126247 "Calpain small subunit 1" P04632 19 36139953-36150353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006872 Approved Approved Nucleoplasm,Cytosol NA NA 9000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA006872: AB_1078382" "unprognostic (1.23e-1)" "unprognostic (1.25e-1)" "unprognostic (2.94e-2)" "unprognostic (1.19e-2)" "unprognostic (1.91e-1)" "unprognostic (2.03e-1)" "unprognostic (2.82e-3)" "unprognostic (1.25e-3)" "unprognostic (2.04e-2)" "unprognostic (6.40e-2)" "unprognostic (1.17e-1)" "unprognostic (5.53e-2)" "unprognostic (7.10e-3)" "unprognostic (1.37e-2)" "unprognostic (1.79e-2)" "unprognostic (1.51e-1)" "unprognostic (4.72e-2)" 425.4 357.9 363.0 171.4 374.4 235.7 371.7 359.4 507.1 368.1 353.9 371.4 263.2 303.5 193.8 761.7 306.6 197.8 692.5 379.8 411.1 488.5 273.5 396.7 167.4 401.0 392.3 267.6 250.9 330.9 317.9 147.3 401.0 357.0 287.6 136.2 374.9 281.4 491.3 211.9 341.4 290.0 356.5 363.6 311.1 273.6 400.3 200.8 329.9 373.4 275.1 354.8 402.5 384.1 395.2 977.6 240.0 342.7 566.3 683.0 48.2 315.8 673.4 631.3 488.1 223.3 572.2 141.9 463.7 1067.5 225.6 207.0 291.3 780.8 514.7 592.4 142.9 166.0 259.7 373.0 655.0 166.7 393.9 740.8 477.9 411.1 577.5 767.3 699.8 173.5 204.4 554.4 978.6 522.7 295.4 301.4 137.9 754.6 490.6 156.5 194.7 262.3 1208.8 368.7 159.1 199.4 385.1 532.0 155.5 279.4 308.6 261.4 460.6 555.5 424.3 188.1 318.7 198.4 277.6 126.8 630.4 225.9 480.8 24.8 50.1 22.6 44.4 75.6 28.5 29.4 30.9 36.4 46.1 32.3 18.7 25.2 25.2 24.6 83.4 58.7 34.7 21.1 363.0 374.4 359.4 507.1 379.8 411.1 401.0 392.3 401.0 356.5 400.3 384.1 172.7 125.0 98.6 10.4 49.3 30.7 76.2 69.1 29.6 21.1 91.7 75.1 149.5 130.1 85.9 163.7 0.0 74.9 107.1 250.1 62.6 226.3 102.9 168.5 118.3 136.6 107.8 47.3 13.4 251.3 87.8 83.3 66.8 234.4 63.4 84.7 157.1 78.4 155.1 16.8 11.9 220.3 52.9 244.6 86.9 230.2 93.2 130.5 39.2 15.9 208.4 78.2 109.2 6.6 21.9 254.2 187.5 76.0 50.2 98.0 243.5 135.3 74.6 33.1 46.0 64.3 92.9 120.1 6.5 109.1 28.8 70.1 62.8 132.2 165.6 112.4 CAPZA2 "CAPPA2, CAPZ" ENSG00000198898 "Capping actin protein of muscle Z-line subunit alpha 2" P47755 7 116811070-116922049 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007470, HPA007643" Uncertain Approved Cytosol No No 4500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA007470: AB_1845985, HPA007643: AB_2667886" "unprognostic (1.37e-2)" "unprognostic (2.25e-3)" "unprognostic (4.16e-2)" "unprognostic (3.16e-1)" "unprognostic (1.53e-1)" "unprognostic (2.63e-3)" "prognostic unfavorable (9.34e-5)" "unprognostic (1.90e-2)" "unprognostic (1.80e-2)" "unprognostic (2.15e-1)" "unprognostic (2.08e-3)" "unprognostic (2.52e-1)" "prognostic favorable (3.65e-6)" "unprognostic (1.40e-1)" "unprognostic (1.08e-1)" "unprognostic (2.91e-3)" "unprognostic (6.58e-2)" 26.3 20.1 17.0 20.0 17.3 43.3 21.8 22.5 25.8 18.0 16.9 24.4 20.4 19.7 19.0 20.8 14.2 20.7 45.7 21.3 17.5 37.3 33.9 23.8 20.1 17.0 17.1 12.6 13.4 19.4 7.5 24.9 20.5 20.3 23.9 13.4 14.6 20.5 64.3 12.3 23.4 28.1 14.5 22.3 20.0 8.7 19.6 16.4 22.8 53.1 17.3 28.1 11.3 18.3 30.0 19.5 19.8 25.2 35.9 37.8 9.8 28.7 41.3 28.8 32.7 14.5 38.1 20.8 46.5 41.3 36.1 18.2 20.4 24.1 45.4 22.7 14.9 31.3 18.0 24.6 22.2 21.2 40.9 30.2 26.9 22.9 21.9 34.8 63.2 12.9 20.8 35.2 57.9 13.0 28.3 35.6 29.5 31.3 16.8 19.7 26.2 42.1 69.3 24.6 20.6 23.5 27.7 104.1 29.7 25.0 14.5 25.0 23.0 47.0 14.6 37.5 28.5 27.7 21.0 39.6 28.0 29.6 34.0 57.3 34.8 45.6 11.1 45.6 13.2 14.4 13.5 11.9 33.2 12.6 12.9 13.1 69.4 15.9 54.9 18.1 18.1 45.3 17.0 17.3 22.5 25.8 21.3 17.5 17.0 17.1 20.5 14.5 19.6 18.3 177.9 73.7 67.4 44.4 109.4 243.1 219.8 224.3 94.4 106.6 85.1 67.3 219.4 71.4 146.5 171.0 27.1 151.7 96.2 147.4 516.5 193.1 9.6 139.4 113.7 189.5 121.2 263.9 59.2 160.3 204.0 124.8 103.5 340.1 126.2 48.8 262.3 110.6 314.1 107.7 48.0 102.6 286.8 238.5 274.9 16.2 74.6 262.9 181.5 64.6 222.4 164.5 72.1 49.8 47.1 193.1 147.5 110.9 83.0 140.9 182.6 519.7 99.7 95.9 92.1 122.8 188.9 43.1 47.0 94.1 218.8 144.1 108.6 78.7 109.9 207.0 CARM1 PRMT4 ENSG00000142453 "Coactivator associated arginine methyltransferase 1" Q86X55 19 10871553-10923075 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 110.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032961, HPA043561, HPA048073, HPA069313" Supported Enhanced Nucleoplasm "Intracellular and membrane" NA NA 19000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB032961: AB_2068446, HPA043561: AB_2678554, HPA048073: AB_2680250, HPA069313: " "unprognostic (9.46e-2)" "unprognostic (3.61e-1)" "unprognostic (2.94e-2)" "unprognostic (2.23e-1)" "unprognostic (2.69e-2)" "unprognostic (3.13e-2)" "unprognostic (1.66e-3)" "unprognostic (3.76e-2)" "unprognostic (7.81e-2)" "unprognostic (6.18e-2)" "unprognostic (9.31e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (7.88e-6)" "unprognostic (1.71e-2)" "unprognostic (6.26e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (8.37e-4)" 20.3 17.1 24.7 19.6 26.6 22.7 17.6 18.9 34.1 30.6 17.2 28.4 17.3 31.7 7.8 36.7 23.4 14.7 25.4 27.6 23.7 18.8 20.1 16.4 19.8 22.8 21.8 21.9 22.3 11.5 14.8 20.4 22.6 20.2 14.3 6.4 20.2 17.5 110.5 22.6 20.9 21.3 19.9 18.6 20.3 45.4 22.6 10.9 13.4 72.4 15.4 26.3 28.0 26.0 62.5 46.8 64.9 88.3 52.5 71.1 63.2 42.8 75.6 63.9 61.0 73.4 21.8 85.2 52.4 77.4 32.1 58.0 65.4 66.2 40.1 98.4 52.7 26.5 29.1 89.9 44.8 39.3 33.9 49.0 42.4 43.8 52.4 35.9 82.1 67.9 65.8 79.2 38.2 116.7 70.0 34.3 81.4 40.7 74.8 97.5 32.8 100.7 38.9 29.7 47.0 45.1 30.7 36.2 43.6 31.7 38.4 35.3 48.7 75.4 43.2 72.3 54.0 75.0 64.1 77.2 51.1 63.8 35.3 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.1 0.5 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.3 0.1 0.1 24.7 26.6 18.9 34.1 27.6 23.7 22.8 21.8 22.6 19.9 22.6 26.0 12.9 9.6 12.2 7.2 11.6 7.8 5.9 4.1 12.0 36.4 14.0 13.7 1.1 14.3 6.5 9.2 52.1 18.5 6.4 42.3 7.9 13.4 32.7 20.1 30.8 12.7 27.6 30.7 12.9 19.7 33.1 13.8 13.7 25.4 1.3 17.8 12.8 27.8 26.7 45.4 10.6 24.9 4.1 20.0 10.9 23.5 28.3 14.8 5.4 5.6 23.9 8.7 4.1 10.6 5.8 24.8 27.2 19.2 11.7 14.1 22.6 9.2 7.4 21.1 6.6 19.6 13.0 23.8 17.5 25.7 7.0 12.0 6.5 6.6 25.7 11.8 CARNS1 "ATPGD1, KIAA1394" ENSG00000172508 "Carnosine synthase 1" A5YM72 11 67414968-67425607 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 278.3;skeletal muscle: 75.5" "Cell type enriched" "Detected in some" 19 "Oligodendrocytes: 447.9" "Group enriched" "Detected in many" 5 "glioma: 4.1;thyroid cancer: 10.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 12 "RPMI-8226: 7.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA038569 Enhanced "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA038569: AB_2676089" "unprognostic (1.07e-4)" "unprognostic (4.33e-3)" "unprognostic (2.00e-2)" "unprognostic (6.15e-2)" "unprognostic (9.45e-2)" "unprognostic (1.05e-1)" "unprognostic (7.28e-2)" "unprognostic (7.54e-3)" "unprognostic (1.29e-1)" "unprognostic (1.82e-1)" "unprognostic (5.19e-3)" "unprognostic (1.00e-1)" "unprognostic (6.14e-6)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (3.83e-3)" "unprognostic (8.33e-2)" 11.7 0.3 62.1 0.4 149.5 0.5 0.7 127.6 119.0 0.7 20.4 0.7 0.4 0.5 1.4 0.9 1.3 0.5 8.8 64.6 89.6 0.8 0.4 0.9 1.2 168.6 137.6 0.9 1.2 0.9 0.6 0.0 145.9 0.7 0.2 0.0 1.3 0.2 75.5 0.6 0.9 0.2 101.8 2.1 7.5 0.2 122.2 0.4 5.6 30.1 0.5 0.5 0.6 278.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.6 0.3 0.1 0.1 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.5 0.3 1.0 0.0 0.6 0.4 1.0 0.0 0.5 0.0 0.0 0.2 0.3 62.1 149.5 127.6 119.0 64.6 89.6 168.6 137.6 145.9 101.8 122.2 278.3 0.6 3.2 0.5 1.0 3.5 0.3 0.2 0.2 0.0 0.0 0.3 0.4 13.5 7.2 0.7 0.0 0.0 0.1 6.1 0.6 0.0 0.5 0.0 0.3 0.2 1.0 3.0 0.0 1.2 0.0 0.1 1.5 23.0 0.5 0.0 0.1 0.4 0.4 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 4.1 2.5 447.9 0.1 0.1 0.4 4.0 0.2 0.2 0.3 0.9 0.5 0.0 3.5 3.0 0.0 0.3 0.1 0.9 0.0 2.3 0.3 0.2 0.1 CARS2 FLJ12118 ENSG00000134905 "Cysteinyl-tRNA synthetase 2, mitochondrial" Q9HA77 13 110641412-110713603 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 221.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-87 MG: 204.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041776 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "HPA041776: AB_2677666" "unprognostic (2.34e-3)" "unprognostic (9.50e-2)" "unprognostic (6.62e-2)" "prognostic favorable (1.84e-4)" "unprognostic (1.98e-1)" "unprognostic (3.54e-3)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (7.82e-2)" "unprognostic (2.11e-3)" "unprognostic (5.75e-2)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.73e-2)" "unprognostic (3.42e-1)" "unprognostic (3.21e-1)" "unprognostic (1.71e-2)" 18.3 24.4 8.8 18.9 9.3 28.4 15.0 16.3 13.3 20.3 15.8 20.8 17.5 16.0 13.7 18.6 16.4 11.1 25.9 9.7 9.3 15.4 19.9 16.7 19.3 9.0 9.3 15.3 15.8 15.0 17.6 12.1 9.7 15.2 13.8 9.2 18.9 12.3 45.8 17.6 18.5 12.6 9.2 17.8 17.2 11.2 9.7 12.9 14.3 26.7 14.1 17.7 15.9 10.5 116.0 37.7 21.2 52.6 55.7 51.7 28.7 49.9 45.7 49.6 60.6 53.5 50.7 53.5 68.4 55.4 75.6 61.0 36.6 63.8 40.2 49.2 58.5 33.5 79.6 63.8 58.5 83.0 39.3 66.7 50.7 43.3 51.8 35.5 36.0 40.9 23.2 16.6 71.2 27.2 37.5 27.6 18.4 88.9 36.8 54.2 15.6 22.3 54.2 33.4 37.7 28.9 40.7 62.0 61.1 22.7 29.8 94.0 32.5 41.8 15.6 53.2 51.6 29.0 35.8 32.4 204.5 50.1 41.9 0.0 2.9 0.4 1.1 3.3 1.2 1.8 0.3 0.4 2.4 0.8 1.1 0.5 1.7 0.4 4.6 2.0 0.4 1.1 8.8 9.3 16.3 13.3 9.7 9.3 9.0 9.3 9.7 9.2 9.7 10.5 18.2 9.6 15.9 24.5 24.4 12.9 24.2 10.3 8.6 21.4 21.8 23.4 39.3 18.6 9.5 27.6 25.0 26.7 28.2 17.6 50.9 17.7 66.5 24.1 21.7 13.6 18.7 10.7 29.2 4.7 29.1 21.6 18.8 27.3 16.5 45.3 9.3 26.6 26.9 23.5 25.1 17.7 12.2 31.2 9.0 221.4 20.5 32.8 12.4 24.4 51.4 24.3 14.4 14.1 26.6 12.1 10.8 18.0 18.6 18.2 23.0 38.1 10.6 25.9 6.6 29.2 24.7 8.6 7.5 22.3 13.5 16.8 19.8 44.2 28.5 17.6 CARTPT CART ENSG00000164326 "CART prepropeptide" Q16568 5 71719275-71721048 "FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Neuropeptide, Neurotransmitter" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 118.6;brain: 183.6" "Group enriched" "Detected in some" 5 "Bipolar cells: 47.4;Early spermatids: 25.4;Prostatic glandular cells: 39.5;Spermatocytes: 55.7" "Cancer enriched" "Detected in many" 9 "breast cancer: 117.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 209.0" "CAB025515, HPA046278, CAB079776" Enhanced Supported "Secreted to blood" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB025515: , CAB079776: , HPA046278: AB_10961570" "unprognostic (1.37e-1)" "unprognostic (1.43e-1)" "unprognostic (2.27e-1)" "unprognostic (3.45e-2)" "unprognostic (6.67e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.14e-1)" 2.4 118.6 85.6 4.4 10.1 0.0 9.3 2.6 48.9 0.0 3.9 16.8 5.5 2.8 0.7 0.3 0.4 0.2 0.1 28.0 134.0 0.3 0.0 0.1 0.0 69.8 111.9 0.1 0.5 0.0 5.2 0.0 183.6 8.6 4.5 21.4 0.1 0.0 0.0 0.1 3.4 15.1 24.5 0.0 14.6 7.1 102.4 0.2 5.4 0.0 0.0 0.0 0.3 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.6 10.1 2.6 48.9 28.0 134.0 69.8 111.9 183.6 24.5 102.4 9.8 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 47.4 0.2 0.3 0.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 25.4 1.6 0.1 1.0 7.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.6 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 39.5 0.0 0.0 0.0 8.1 0.0 0.0 0.1 55.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 CASQ1 "CASQ, PDIB1" ENSG00000143318 "Calsequestrin 1" P31415 1 160190575-160201886 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 64 "skeletal muscle: 4442.6;tongue: 1892.7" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 17.6;Rod photoreceptor cells: 25.2;Skeletal myocytes: 20.6" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "BEWO: 19.3;HDLM-2: 38.5;RT4: 67.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007845, CAB015170, HPA026823" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA 270000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Mitochondria" "CAB015170: AB_2071451, HPA007845: AB_1078388, HPA026823: AB_10603557" "unprognostic (1.87e-2)" "unprognostic (3.97e-3)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" "unprognostic (2.03e-2)" "unprognostic (6.85e-2)" "unprognostic (1.96e-2)" "unprognostic (4.65e-3)" "unprognostic (3.85e-2)" "unprognostic (1.01e-2)" "unprognostic (2.87e-2)" "unprognostic (3.01e-2)" "unprognostic (3.21e-3)" "unprognostic (9.04e-4)" "unprognostic (1.80e-1)" "unprognostic (1.58e-1)" "prognostic favorable (8.93e-5)" 0.9 0.4 5.1 0.8 6.0 1.5 1.4 4.9 10.0 0.5 3.3 3.3 0.5 1.7 0.3 43.1 1.9 1.2 44.9 6.5 3.1 0.3 0.4 0.7 3.0 3.7 3.9 0.4 0.3 0.2 1.0 6.2 3.2 16.2 0.5 49.7 16.7 5.0 4442.6 1.0 1.9 7.4 3.1 1.3 0.8 5.7 3.6 0.5 0.6 1892.7 1.0 5.7 0.9 6.2 0.0 0.0 0.5 0.0 0.2 0.0 19.3 0.0 0.2 0.0 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 38.5 0.4 0.1 0.0 0.0 0.1 0.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.7 0.4 0.1 0.0 0.2 0.3 0.2 0.0 67.4 0.0 0.1 0.3 0.2 0.0 3.5 0.1 0.0 0.0 0.2 0.3 0.1 0.0 0.7 0.8 0.3 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.1 6.0 4.9 10.0 6.5 3.1 3.7 3.9 3.2 3.1 3.6 6.2 0.1 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.0 1.9 0.7 0.9 17.6 0.0 0.0 0.0 2.1 3.0 0.1 0.0 0.0 0.1 3.0 0.1 0.1 0.2 0.0 0.0 2.0 0.0 4.9 0.3 0.0 0.1 3.8 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.3 0.6 0.6 0.2 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 25.2 0.0 20.6 0.6 1.2 1.9 0.0 0.0 4.5 0.1 0.1 0.0 0.3 CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1056.7" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 777.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "HSkMC: 13.6" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in all" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027285: AB_1845933, HPA055298: AB_2682777" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (9.70e-3)" "unprognostic (1.28e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.03e-4)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (7.20e-3)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.25e-5)" 31.9 3.0 3.5 6.4 2.3 0.0 8.9 2.8 4.0 8.0 2.0 59.8 3.3 17.2 6.5 38.5 14.7 6.6 1056.7 1.8 3.6 3.5 0.6 5.3 0.8 1.9 4.8 5.3 1.2 1.6 0.9 1.6 2.1 13.8 17.0 0.3 7.6 20.2 182.1 4.9 9.1 39.1 1.9 0.8 14.2 1.5 6.4 1.6 4.1 165.0 1.3 43.9 6.9 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 2.3 2.8 4.0 1.8 3.6 1.9 4.8 2.1 1.9 6.4 1.9 2.7 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.6 0.2 0.1 0.4 777.8 0.0 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 15.5 0.3 0.0 4.8 0.0 0.0 0.7 0.0 0.3 17.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 20.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 1.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 92.1 11.0 73.4 0.1 0.4 0.2 0.3 0.0 0.1 0.0 0.0 0.0 CATSPERG "C19orf15, DKFZp434A1022, FLJ46353" ENSG00000099338 "Cation channel sperm associated auxiliary subunit gamma" Q6ZRH7 19 38335775-38370943 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 31.3" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Gastric mucus-secreting cells: 27.0;Late spermatids: 49.2;Proximal enterocytes: 20.7;Spermatocytes: 28.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 1.4;HMC-1: 1.8;MCF7: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052777 Approved Nucleoplasm,Nucleoli,Cytosol "Secreted in male reproductive system" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" Nucleoli "Nucleoplasm, Cytosol" "HPA052777: " "unprognostic (8.50e-5)" "unprognostic (5.12e-2)" "unprognostic (3.57e-3)" "unprognostic (1.51e-1)" "unprognostic (2.63e-1)" "unprognostic (3.18e-1)" "unprognostic (2.60e-1)" "unprognostic (2.87e-3)" "unprognostic (1.00e-1)" "unprognostic (2.92e-2)" "unprognostic (1.06e-1)" "unprognostic (2.50e-1)" "unprognostic (4.37e-4)" "unprognostic (9.99e-2)" "unprognostic (2.01e-1)" "unprognostic (4.61e-2)" "unprognostic (1.07e-3)" 0.2 0.1 0.5 0.1 0.8 0.3 0.4 0.8 0.9 0.4 0.2 0.2 0.4 0.2 0.7 0.2 0.5 0.1 0.1 0.4 0.5 0.2 0.2 0.3 0.3 0.7 2.8 0.4 0.2 0.2 0.2 0.1 0.7 0.4 0.2 0.2 0.3 0.2 0.2 1.0 0.3 0.1 0.4 0.2 0.2 31.3 0.8 0.2 0.5 0.0 0.2 0.1 0.2 1.1 0.0 0.1 0.0 0.6 0.2 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.3 0.0 0.1 0.2 0.0 0.3 0.0 0.5 0.0 1.5 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.3 0.7 0.0 0.1 0.2 0.1 0.3 0.0 0.2 0.1 0.0 0.1 0.0 0.3 0.2 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.5 0.0 0.7 0.1 0.1 0.0 0.5 0.8 0.8 0.9 0.4 0.5 0.7 2.8 0.7 0.4 0.8 1.1 4.9 0.0 2.7 2.6 3.6 2.5 2.4 1.0 4.6 1.3 4.8 8.0 3.0 1.5 0.6 1.8 0.0 1.7 5.1 10.1 0.0 1.0 29.4 4.9 4.4 2.7 1.8 3.2 4.3 0.7 0.3 3.0 27.0 8.8 1.3 2.0 2.5 0.3 3.2 1.7 3.8 3.9 2.0 1.2 3.1 49.2 1.8 3.3 0.0 1.9 3.9 1.9 10.3 3.0 17.0 0.4 5.6 2.2 2.2 1.9 20.7 0.9 1.3 1.4 0.0 5.3 3.7 28.9 3.7 4.9 1.8 1.4 3.4 1.9 3.5 1.8 CBARP "BARP, C19orf26, DOS, MGC40084" ENSG00000099625 "CACN subunit beta associated regulatory protein" Q8N350 19 1228287-1238027 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.3;pituitary gland: 22.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 21.8;Early spermatids: 55.9;Late spermatids: 97.4;Spermatocytes: 54.8" "Cancer enhanced" "Detected in many" "glioma: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012777 Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA012777: AB_2067005" "unprognostic (1.31e-1)" "unprognostic (4.57e-3)" "unprognostic (1.34e-1)" "unprognostic (1.10e-2)" "unprognostic (3.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.54e-5)" "unprognostic (3.48e-1)" "unprognostic (2.17e-1)" "unprognostic (4.58e-2)" "unprognostic (2.86e-3)" "unprognostic (3.03e-1)" "unprognostic (5.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.12e-1)" "unprognostic (2.40e-1)" "unprognostic (7.42e-5)" 1.4 2.6 6.0 0.1 9.8 0.0 0.4 2.0 15.3 0.7 0.0 0.6 0.1 0.5 0.0 1.4 0.5 0.1 1.7 12.3 3.1 2.3 0.3 1.0 0.0 5.6 1.3 4.9 0.4 0.0 22.3 0.1 1.3 0.8 0.0 0.3 0.4 0.1 0.4 3.1 0.2 0.0 0.0 0.1 0.4 1.7 1.8 0.0 0.6 0.0 0.0 0.3 0.9 0.0 0.3 0.4 1.1 3.1 0.1 0.5 0.4 2.7 0.8 0.5 0.5 1.1 0.1 0.0 2.7 0.5 0.3 0.9 0.4 0.6 0.1 0.5 0.7 0.1 1.1 0.9 1.4 0.0 1.0 0.6 0.2 0.6 0.1 0.5 0.4 0.5 1.7 0.0 0.3 2.3 0.0 0.6 1.6 0.1 1.2 2.0 0.4 0.2 0.1 0.2 1.4 4.2 0.0 0.0 3.1 0.1 0.4 0.5 1.2 0.7 2.6 2.3 0.7 0.1 0.2 0.0 0.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 9.8 2.0 15.3 12.3 3.1 5.6 1.3 1.3 0.0 1.8 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 1.2 21.8 1.7 1.8 0.0 1.5 0.0 0.0 2.1 0.0 0.6 0.0 1.9 0.1 55.9 0.9 2.2 0.7 0.0 0.0 0.0 0.2 0.1 1.2 1.1 1.6 0.0 0.9 1.4 0.1 0.3 3.3 0.0 0.0 0.0 0.8 0.0 97.4 1.8 1.2 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.9 0.0 0.2 0.0 1.7 0.0 0.7 1.4 54.8 7.0 1.1 0.0 0.0 0.3 0.1 0.0 0.3 CBLIF "GIF, IF, IFMH, INF, TCN3" ENSG00000134812 "Cobalamin binding intrinsic factor" P27352 11 59829273-59845499 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1859 "stomach 1: 1575.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "stomach cancer: 10.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039908, HPA040774" Enhanced "Secreted to digestive system" NA NA "Cluster 4: Stomach - Digestion" "HPA039908: AB_10796335, HPA040774: AB_10795626" "unprognostic (2.78e-4)" "unprognostic (1.04e-1)" "unprognostic (2.45e-1)" "unprognostic (3.59e-1)" "unprognostic (1.66e-1)" 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.6 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1575.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CBLN1 ENSG00000102924 "Cerebellin 1 precursor" P23435 16 49277917-49281838 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 114.2;testis: 31.9" "Cell type enhanced" "Detected in some" "Early spermatids: 100.9;Late spermatids: 291.0;Spermatocytes: 61.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.5" "Region enriched" "Detected in all" 4 "cerebellum: 114.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "NTERA-2: 40.0;SCLC-21H: 126.0" "Region enriched" "Detected in all" 9 "cerebellum: 613.4" "Region enriched" "Detected in many" 13 "cerebellum: 369.4" "Secreted in brain" NA NA 6000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.39e-2)" "unprognostic (1.88e-2)" "unprognostic (1.53e-1)" "unprognostic (3.16e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-2)" "unprognostic (9.65e-3)" "unprognostic (1.18e-2)" "unprognostic (6.31e-2)" "unprognostic (1.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.04e-2)" "unprognostic (7.68e-2)" "unprognostic (2.45e-1)" "unprognostic (1.06e-2)" "prognostic favorable (7.10e-4)" "unprognostic (1.60e-2)" 11.8 1.0 4.6 0.2 3.2 0.0 3.8 114.2 7.1 2.1 0.9 0.7 1.0 5.8 0.4 1.0 1.3 7.5 4.6 2.4 23.4 0.2 1.0 0.1 0.8 10.7 18.4 1.3 2.8 0.2 4.2 0.0 12.7 0.5 0.7 3.5 0.6 0.6 0.9 0.8 1.3 1.7 4.8 0.1 0.7 31.9 27.0 0.2 2.3 1.7 2.8 1.4 0.5 5.4 0.0 0.0 0.6 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 2.7 2.6 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 126.0 3.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 3.2 114.2 7.1 2.4 23.4 10.7 18.4 12.7 4.8 27.0 5.4 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.3 2.2 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 100.9 0.1 2.4 6.7 13.2 0.0 0.6 0.4 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.7 4.7 0.5 0.0 0.0 0.0 291.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.5 0.4 0.2 0.0 0.4 0.0 0.1 0.3 0.0 0.0 1.8 26.3 0.1 19.2 61.7 5.8 0.0 0.1 0.0 0.0 8.8 0.2 0.0 CBLN2 ENSG00000141668 "Cerebellin 2 precursor" Q8IUK8 18 72536680-72638521 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 32.5" "Cell type enriched" "Detected in some" 13 "Excitatory neurons: 508.3" "Cancer enriched" "Detected in single" 7 "breast cancer: 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 54.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in brain" NA NA 1400000 "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.03e-2)" "unprognostic (3.52e-1)" "unprognostic (1.13e-3)" "unprognostic (9.09e-5)" "unprognostic (7.10e-2)" "unprognostic (6.27e-3)" "unprognostic (7.39e-2)" "unprognostic (2.17e-1)" "unprognostic (1.37e-4)" "unprognostic (5.01e-4)" "unprognostic (8.15e-2)" "unprognostic (6.07e-4)" "unprognostic (7.19e-2)" "unprognostic (1.63e-1)" "unprognostic (1.18e-1)" "unprognostic (4.93e-2)" 0.4 0.2 7.9 0.3 17.3 0.0 0.1 0.0 32.5 0.3 0.0 1.8 1.5 0.0 0.0 0.0 0.1 0.0 0.1 3.3 0.2 2.5 0.4 0.0 0.0 5.9 4.5 0.1 0.0 0.0 0.2 0.0 8.7 0.9 1.5 5.1 0.0 5.1 0.0 0.8 2.5 0.8 0.0 0.0 0.1 0.2 13.8 0.0 0.0 0.0 0.7 0.1 0.0 12.8 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 54.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 17.3 0.0 32.5 3.3 0.2 5.9 4.5 8.7 0.0 13.8 12.8 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.7 0.3 37.8 0.0 508.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.3 0.6 0.6 0.0 0.0 10.3 0.0 0.5 0.0 9.5 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.3 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 CBLN3 ENSG00000139899 "Cerebellin 3 precursor" Q6UW01 14 24426545-24430954 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 93.9" "Cell type enhanced" "Detected in some" "dendritic cells: 3.0;Theca cells: 5.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 11 "cerebellum: 93.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 13.4;HDLM-2: 17.2;HSkMC: 23.3;Karpas-707: 18.3;U-266/70: 12.8" "Region enriched" "Detected in many" 25 "cerebellum: 429.5" "Region enriched" "Detected in many" 42 "cerebellum: 446.5" HPA041266 Enhanced Supported Approved Nucleoplasm "Secreted in brain" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA041266: AB_10674430" "unprognostic (5.02e-2)" "unprognostic (3.26e-1)" "unprognostic (1.43e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (4.39e-4)" "unprognostic (5.39e-3)" "unprognostic (1.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.16e-2)" "unprognostic (9.76e-2)" "unprognostic (6.20e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (6.20e-6)" "unprognostic (2.75e-2)" "unprognostic (2.63e-1)" "unprognostic (1.72e-1)" "unprognostic (9.02e-2)" 7.3 17.1 2.7 8.3 3.0 0.6 4.7 93.9 7.0 4.6 2.1 4.2 2.1 2.7 7.4 2.9 4.0 5.6 3.7 2.4 3.3 4.4 6.0 4.8 13.7 3.9 5.8 10.1 2.0 2.9 4.2 3.7 8.4 4.5 2.1 0.5 4.3 3.1 1.8 3.5 5.4 2.2 3.2 13.7 3.3 5.1 3.4 3.9 4.5 0.6 9.1 4.9 4.6 4.8 1.5 1.3 0.7 2.5 6.2 13.4 0.4 5.5 11.1 2.1 2.7 0.7 2.6 2.4 1.2 3.4 2.4 0.3 0.8 2.9 1.4 17.2 0.6 0.0 5.2 1.1 3.3 0.4 0.9 23.3 1.3 2.7 2.1 8.8 1.9 1.0 0.7 18.3 2.8 0.8 0.0 0.7 0.1 1.5 1.5 0.0 0.0 1.8 1.2 0.5 0.9 0.5 0.5 0.1 0.8 0.3 0.8 0.6 8.7 7.7 1.5 3.2 0.3 12.8 3.2 2.7 0.4 1.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.0 93.9 7.0 2.4 3.3 3.9 5.8 8.4 3.2 3.4 4.8 1.4 0.0 0.0 0.0 2.6 0.4 0.6 1.5 0.0 0.0 0.8 1.0 0.5 0.0 0.4 0.0 0.0 0.9 3.0 0.8 0.0 1.1 0.0 0.3 2.0 0.8 0.0 0.4 0.3 1.1 0.6 2.6 0.0 0.5 0.0 0.9 0.0 0.2 0.9 0.0 0.1 0.5 0.0 0.3 0.4 0.3 2.5 0.7 0.0 1.0 2.6 1.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 0.5 0.9 0.8 1.4 0.2 0.0 0.7 1.4 0.0 0.2 0.2 0.6 0.8 0.2 5.7 0.6 0.6 CBLN4 "CBLNL1, dJ885A10.1" ENSG00000054803 "Cerebellin 4 precursor" Q9NTU7 20 55997357-56005519 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 17.8;brain: 19.3;epididymis: 8.8" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 8.9;Excitatory neurons: 26.9;Inhibitory neurons: 31.6;Peritubular cells: 38.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 50 "SH-SY5Y: 9.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074497 Supported "Secreted in brain" NA NA 10000000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA074497: " "unprognostic (3.61e-1)" "unprognostic (8.43e-3)" "unprognostic (2.43e-1)" "unprognostic (1.61e-2)" "unprognostic (1.99e-1)" "unprognostic (4.00e-1)" "unprognostic (3.25e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-1)" "unprognostic (3.88e-1)" "unprognostic (9.63e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-3)" "unprognostic (3.22e-4)" "unprognostic (7.50e-2)" "unprognostic (3.58e-2)" "unprognostic (1.79e-3)" 1.6 17.8 14.6 0.1 3.4 0.0 1.4 0.0 9.4 1.9 0.0 0.0 0.0 0.7 8.8 0.1 3.8 0.5 0.0 14.4 5.8 0.6 0.9 0.7 0.0 0.7 19.3 2.0 0.7 0.3 0.1 0.2 2.4 0.1 0.0 0.3 0.1 0.3 0.3 0.0 0.1 0.3 0.0 0.0 0.3 2.0 12.2 0.1 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 3.4 0.0 9.4 14.4 5.8 0.7 19.3 2.4 0.0 12.2 0.2 0.1 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 0.2 8.9 0.0 26.9 0.0 0.0 5.2 0.0 0.1 0.0 0.0 0.0 1.3 0.1 1.7 31.6 0.0 0.0 0.0 0.0 1.0 2.1 0.2 0.0 1.9 0.0 0.2 0.0 1.0 2.0 0.0 0.0 38.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 CBWD1 ENSG00000172785 "COBW domain containing 1" Q9BRT8 9 121038-179147 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 185.1" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (3.75e-2)" "unprognostic (3.47e-2)" "unprognostic (5.23e-2)" "unprognostic (4.15e-2)" "unprognostic (1.39e-1)" "unprognostic (2.67e-2)" "unprognostic (3.91e-2)" "unprognostic (3.72e-1)" "unprognostic (4.15e-2)" "unprognostic (2.07e-3)" "unprognostic (1.82e-1)" "unprognostic (4.68e-2)" "unprognostic (5.80e-7)" "unprognostic (7.19e-2)" "unprognostic (1.04e-1)" "unprognostic (8.94e-2)" "unprognostic (4.98e-3)" 18.6 34.4 8.7 15.3 9.2 13.0 19.9 10.6 11.1 14.3 13.0 16.9 13.3 13.7 20.8 26.8 14.6 10.6 20.7 9.0 10.2 40.1 26.8 16.1 13.4 9.0 9.0 15.4 30.0 38.3 19.4 22.2 9.2 19.9 15.2 27.5 23.7 12.2 21.8 22.3 14.1 12.2 9.0 16.9 19.1 16.4 9.1 13.2 25.4 17.6 20.1 23.4 17.1 9.9 43.3 16.1 22.7 12.2 29.1 26.2 50.3 22.2 14.6 30.4 23.0 23.4 16.1 39.4 28.3 8.2 18.4 7.3 11.3 21.1 32.4 67.8 38.9 0.4 39.1 72.6 31.5 115.1 17.2 23.5 9.9 7.3 59.0 19.5 32.9 19.7 13.6 84.3 25.2 52.1 25.1 185.1 22.9 37.6 34.6 47.7 34.6 75.8 39.4 120.7 40.8 24.8 45.8 16.8 17.8 55.5 35.6 109.2 34.4 16.0 22.9 20.8 19.7 10.1 14.6 44.6 39.6 60.6 19.2 3.6 65.7 19.3 10.3 75.6 16.9 21.1 18.6 16.8 74.1 15.7 16.2 17.7 10.2 12.8 60.8 19.6 18.1 48.3 8.7 9.2 10.6 11.1 9.0 10.2 9.0 9.0 9.2 9.0 9.1 9.9 19.5 54.5 50.1 8.1 41.2 47.7 29.9 47.6 97.9 50.8 49.4 37.6 51.8 30.0 49.8 35.0 108.4 96.3 17.7 20.4 35.2 79.9 51.7 14.9 10.1 23.0 31.2 44.6 17.0 118.5 41.2 23.0 34.7 11.9 32.8 26.7 20.7 19.0 32.0 38.7 17.1 39.0 50.8 25.1 38.0 16.4 18.0 37.9 32.0 18.7 81.5 32.2 18.6 5.5 16.7 66.9 38.2 13.2 90.0 32.0 49.5 73.6 31.0 63.5 32.9 20.2 27.8 48.6 28.1 83.8 50.6 124.8 23.5 24.1 62.3 24.9 CCAR2 "DBC-1, DBC1, KIAA1967, NET35" ENSG00000158941 "Cell cycle and apoptosis regulator 2" Q8N163 8 22604632-22621514 "Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, DNA damage, mRNA processing, mRNA splicing, Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Metalloenzyme inhibitor, Repressor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019907, HPA019943, CAB072827, CAB072828" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA 19000 "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nuclear bodies" "CAB072827: , CAB072828: , HPA019907: AB_1852452, HPA019943: AB_1852454" "unprognostic (3.42e-2)" "unprognostic (5.78e-3)" "unprognostic (2.46e-3)" "unprognostic (1.33e-2)" "unprognostic (6.87e-2)" "unprognostic (2.23e-2)" "unprognostic (5.13e-2)" "unprognostic (8.56e-2)" "unprognostic (2.97e-1)" "unprognostic (1.77e-1)" "unprognostic (2.32e-2)" "unprognostic (1.54e-2)" "prognostic favorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (2.46e-1)" "unprognostic (7.54e-2)" "unprognostic (1.77e-1)" 64.1 68.3 39.2 75.4 44.2 145.5 64.4 40.2 52.4 65.6 45.6 68.5 52.1 75.0 33.0 63.4 67.9 59.7 52.0 47.0 33.8 54.8 41.1 61.4 86.7 36.9 42.3 74.6 56.4 59.8 65.1 54.0 38.6 61.1 45.6 59.8 61.5 46.9 101.4 89.0 69.3 44.9 34.7 85.6 60.0 89.4 39.6 96.0 60.6 43.5 74.3 65.4 57.6 47.9 133.7 242.8 230.8 120.8 89.5 74.7 154.0 127.7 124.9 184.3 163.9 219.5 107.4 218.6 156.4 140.5 169.6 163.2 214.5 151.9 132.9 89.2 128.2 259.1 189.5 172.8 82.9 143.6 212.0 77.8 133.1 147.0 90.0 106.4 134.4 194.4 276.2 134.8 138.0 157.5 435.0 150.5 337.6 143.2 88.1 286.7 190.7 116.8 95.2 311.7 115.1 267.6 143.7 163.0 112.6 110.7 148.8 133.2 219.3 135.8 178.4 165.3 171.1 98.5 134.0 261.4 152.7 123.4 215.7 25.9 16.2 23.5 34.8 26.6 29.4 18.7 26.5 26.6 16.6 17.5 25.7 28.4 5.7 19.9 35.6 15.5 32.6 25.8 39.2 44.2 40.2 52.4 47.0 33.8 36.9 42.3 38.6 34.7 39.6 47.9 14.4 16.0 4.2 11.1 14.1 13.9 9.5 12.2 17.6 12.9 13.5 13.1 7.5 15.7 9.4 16.5 16.7 27.3 19.4 24.1 9.8 18.1 4.7 14.1 12.3 13.1 22.2 16.4 12.5 18.0 22.2 12.8 18.8 14.3 8.8 20.2 11.7 12.0 15.7 10.1 11.9 19.6 14.2 11.9 8.5 7.3 14.9 11.0 12.4 10.3 11.2 15.9 20.6 11.1 10.3 23.6 10.4 12.0 14.8 11.7 14.4 9.4 19.5 12.9 19.7 12.4 12.2 30.0 24.1 16.9 15.3 23.7 19.3 23.5 21.7 10.5 CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.1;Rod photoreceptor cells: 38.2;Theca cells: 78.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "BJ: 101.2;BJ hTERT+: 103.2;BJ hTERT+ SV40 Large T+ RasG12V: 96.4;HBF TERT88: 113.3;hTERT-HME1: 153.2;LHCN-M2: 176.9;TIME: 93.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Supported "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" 4.1 10.2 2.7 1.2 3.4 0.5 1.8 2.2 3.0 10.5 0.7 16.7 1.1 6.9 0.5 2.8 8.3 1.3 2.1 6.5 1.1 3.3 5.7 9.9 1.3 0.2 1.9 33.5 1.1 2.9 0.4 0.5 0.3 2.4 2.8 1.1 0.6 4.0 15.3 3.0 2.5 3.2 0.2 0.5 1.6 0.6 3.7 1.2 0.9 0.9 0.7 0.8 1.3 1.5 20.6 1.9 0.0 0.2 15.1 47.2 30.7 101.2 103.2 73.5 96.4 0.3 0.3 0.4 0.2 40.6 16.7 2.3 0.2 65.5 113.3 0.4 0.3 0.2 0.4 0.3 35.1 0.3 0.2 32.0 2.9 57.0 153.2 31.2 3.6 0.3 0.2 0.5 176.9 0.6 0.1 0.2 0.3 0.0 0.6 0.1 0.2 0.2 3.9 2.0 0.4 0.7 0.3 0.2 0.9 7.2 0.3 0.5 93.3 0.2 10.0 15.3 0.3 0.3 0.3 0.2 5.0 0.3 2.4 9.2 0.2 0.5 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.5 0.4 0.1 0.2 0.1 0.1 2.7 3.4 2.2 3.0 6.5 1.1 0.2 1.9 0.3 0.2 3.7 1.5 1.5 3.2 1.3 3.9 0.2 4.6 2.0 1.0 2.2 6.4 0.8 0.4 1.6 2.8 1.9 0.0 8.4 1.0 0.2 0.2 0.0 0.2 0.8 8.8 5.1 2.2 0.0 0.0 56.1 0.2 1.3 14.5 0.0 0.6 1.3 6.8 9.7 0.2 0.4 15.2 15.1 0.0 0.0 1.0 8.9 1.1 9.6 0.5 7.2 1.0 0.2 2.4 0.0 0.5 0.7 0.3 0.0 0.4 0.1 1.5 0.1 0.1 0.9 38.2 0.0 1.6 5.9 0.4 0.9 0.2 4.3 0.8 1.2 78.0 0.1 0.9 CCDC112 MGC39633 ENSG00000164221 "Coiled-coil domain containing 112" Q8NEF3 5 115267190-115296693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 40.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 201.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 113.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045120, HPA050621" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA045120: AB_2679222, HPA050621: AB_2681191" "unprognostic (1.88e-2)" "unprognostic (5.10e-2)" "unprognostic (4.63e-2)" "unprognostic (5.60e-3)" "unprognostic (2.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.32e-6)" "unprognostic (4.30e-2)" "unprognostic (3.24e-1)" "unprognostic (4.41e-2)" "unprognostic (3.33e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (1.51e-6)" "unprognostic (7.00e-2)" "unprognostic (2.79e-2)" "unprognostic (8.61e-2)" "unprognostic (4.10e-3)" 4.3 3.6 5.7 5.3 6.3 7.3 6.0 7.4 7.3 4.5 2.6 9.1 7.2 5.6 6.2 4.5 4.1 3.1 6.0 5.8 6.6 2.8 1.2 5.5 4.6 6.4 5.5 2.1 10.2 4.5 4.6 2.4 6.3 6.7 9.3 7.9 6.5 5.0 4.3 4.9 6.3 5.4 5.7 4.6 6.4 40.7 5.9 3.7 4.0 2.5 4.2 3.8 3.6 7.8 12.0 5.9 11.5 18.5 7.1 14.0 2.9 10.5 5.3 7.7 8.7 2.6 6.7 14.8 8.9 7.2 11.4 7.5 12.1 6.0 16.0 12.0 10.1 9.8 8.8 3.8 9.7 12.9 4.8 6.4 7.2 9.8 13.0 8.8 12.1 13.1 4.1 11.6 10.8 9.3 19.2 11.4 13.1 11.0 11.0 20.6 14.5 113.7 7.7 4.2 17.9 23.5 11.5 7.2 32.8 7.8 12.2 18.9 12.6 10.1 6.9 19.7 14.8 13.2 13.2 3.0 6.7 9.9 6.0 0.3 5.0 11.0 2.9 4.0 3.3 2.8 2.2 2.5 5.4 4.0 2.8 1.9 3.2 3.0 4.9 10.2 0.1 2.1 5.7 6.3 7.4 7.3 5.8 6.6 6.4 5.5 6.3 5.7 5.9 7.8 15.7 16.0 14.0 16.0 19.2 14.1 5.0 6.0 8.0 29.2 19.4 18.4 17.6 8.6 8.4 5.5 10.4 0.7 19.5 23.6 5.9 28.2 8.5 23.0 21.4 12.4 40.6 20.8 26.4 25.9 2.0 11.5 14.3 12.3 9.5 15.0 7.9 3.1 32.7 10.1 15.2 33.4 6.1 28.6 31.5 18.5 4.1 31.5 14.2 15.0 36.6 11.0 11.3 21.1 54.7 27.1 18.7 4.1 27.3 8.0 11.8 4.4 11.7 24.9 13.1 18.5 18.2 201.8 73.3 13.8 22.6 0.5 9.2 5.5 32.8 3.4 CCDC117 FLJ33814 ENSG00000159873 "Coiled-coil domain containing 117" Q8IWD4 22 28772674-28789301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 104.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000826 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Microtubules, Cytosol" "HPA000826: AB_1078417" "unprognostic (1.71e-1)" "unprognostic (2.04e-2)" "unprognostic (1.61e-3)" "unprognostic (9.07e-2)" "unprognostic (3.84e-2)" "unprognostic (1.26e-1)" "unprognostic (1.62e-1)" "unprognostic (1.35e-2)" "unprognostic (8.43e-2)" "unprognostic (7.74e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" "unprognostic (1.10e-3)" "unprognostic (8.25e-2)" 9.5 10.2 11.8 12.7 12.7 21.8 11.9 15.7 22.8 14.2 13.4 11.2 11.8 11.5 8.0 8.2 9.1 9.5 7.9 11.6 12.5 9.8 24.2 9.4 18.2 11.6 11.8 12.5 9.4 12.6 6.7 19.1 11.5 9.8 11.2 10.6 18.3 9.3 16.9 8.2 9.4 9.7 11.8 12.6 10.0 36.6 13.1 17.9 10.9 20.7 20.3 10.6 7.5 17.6 19.9 16.0 32.2 31.7 20.6 18.0 25.5 19.7 23.9 33.4 29.2 24.6 9.4 61.7 8.6 18.0 14.2 20.2 47.8 7.8 31.6 33.6 31.4 25.2 17.3 36.6 14.1 40.6 30.9 12.2 16.8 19.3 11.9 14.9 23.5 20.0 36.0 26.6 15.2 25.6 24.1 32.8 26.4 35.3 7.7 48.1 50.8 27.0 14.9 7.6 12.3 16.4 30.4 28.0 12.7 38.0 34.9 17.4 13.7 41.7 28.3 13.3 15.3 61.7 68.9 51.2 14.6 21.9 18.1 13.5 14.6 15.3 10.0 13.2 10.2 10.0 8.3 9.8 14.6 12.4 14.5 11.8 6.7 25.3 12.9 12.7 11.6 14.9 11.8 12.7 15.7 22.8 11.6 12.5 11.6 11.8 11.5 11.8 13.1 17.6 11.1 22.4 14.3 4.2 18.3 10.6 14.4 4.3 6.2 7.7 21.9 14.2 10.4 15.7 8.5 14.7 14.6 16.5 20.4 13.2 7.9 9.9 104.0 20.7 32.5 15.5 20.4 17.4 6.6 10.0 17.8 14.3 6.6 31.0 17.2 11.9 10.8 42.3 9.3 3.3 7.1 12.3 4.1 18.9 19.0 38.2 12.8 15.4 17.8 7.5 14.7 6.2 21.6 4.5 12.8 9.7 8.9 7.9 26.4 22.6 9.0 12.5 13.8 15.2 0.0 9.6 16.1 49.5 48.5 9.5 10.9 24.6 14.7 9.0 12.4 22.3 CCDC134 FLJ22349 ENSG00000100147 "Coiled-coil domain containing 134" Q9H6E4 22 41800679-41832164 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 18.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003936 Approved "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA003936: AB_1078419" "unprognostic (2.09e-2)" "unprognostic (1.00e-1)" "unprognostic (3.82e-2)" "prognostic favorable (4.09e-4)" "unprognostic (1.73e-1)" "unprognostic (3.85e-2)" "prognostic unfavorable (7.42e-7)" "unprognostic (4.35e-1)" "unprognostic (1.69e-1)" "unprognostic (3.08e-1)" "unprognostic (3.30e-2)" "unprognostic (7.32e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.24e-3)" "unprognostic (2.52e-2)" "unprognostic (5.47e-1)" "unprognostic (6.63e-2)" 1.4 10.2 2.2 3.7 2.5 12.6 2.7 9.0 2.4 2.0 2.3 2.6 3.3 1.8 10.5 2.7 3.6 1.3 2.1 2.0 1.9 2.8 2.7 2.4 4.0 3.3 2.7 2.1 3.7 5.0 1.6 2.7 2.8 2.5 2.8 5.8 4.3 2.6 2.8 4.6 3.6 1.8 1.8 2.9 4.2 6.1 3.8 3.7 2.5 2.3 4.6 1.6 1.4 3.5 8.6 6.4 7.3 11.0 4.4 1.3 5.9 7.1 3.8 9.4 11.2 9.7 5.4 8.6 12.1 5.0 7.2 9.5 7.7 5.6 7.0 7.5 11.2 7.5 19.4 7.1 2.3 10.8 8.7 2.2 2.5 11.6 2.5 4.3 4.4 7.5 4.5 16.1 6.1 5.8 7.0 7.3 4.9 11.5 5.4 12.6 11.6 11.0 7.7 7.1 3.6 3.2 13.8 10.3 5.3 4.1 12.6 5.5 3.6 7.5 11.6 4.5 12.0 18.3 11.9 6.8 7.2 6.6 12.2 1.1 3.3 6.9 4.1 5.1 2.9 3.8 2.6 3.5 1.5 2.5 4.7 3.3 1.9 3.6 5.2 1.6 5.2 2.2 2.2 2.5 9.0 2.4 2.0 1.9 3.3 2.7 2.8 1.8 3.8 3.5 1.0 3.2 2.0 6.8 2.5 0.3 1.5 2.4 0.6 1.1 2.1 1.5 0.8 2.8 1.5 3.7 2.1 4.0 3.0 3.3 0.0 5.0 0.8 3.5 1.3 1.7 0.0 2.5 6.0 1.9 18.2 1.7 3.6 2.5 0.0 2.1 0.4 1.6 4.3 0.0 6.4 2.0 0.0 1.0 0.7 0.9 0.6 1.7 1.8 10.3 4.1 0.7 2.1 9.0 5.8 2.6 1.9 0.4 7.9 1.8 3.5 1.4 2.6 2.3 0.0 1.7 2.1 3.7 1.3 1.8 0.0 2.9 2.1 3.3 3.1 1.6 CCDC141 "CAMDI, FLJ39502" ENSG00000163492 "Coiled-coil domain containing 141" Q6ZP82 2 178829757-179050086 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 74.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 29.5;Bipolar cells: 28.1;Cardiomyocytes: 118.2;Cholangiocytes: 27.1;Early spermatids: 37.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 15.0" "Group enriched" "Detected in many" 9 "B-cells: 8.1;T-cells: 15.0" "Cell line enhanced" "Detected in some" "CACO-2: 4.6;Daudi: 3.0;HEL: 6.9;RH-30: 3.6;U-266/70: 4.3;U-698: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012718 Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA012718: AB_2072055" "unprognostic (1.58e-1)" "unprognostic (1.85e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-1)" "unprognostic (8.62e-3)" "unprognostic (4.25e-2)" "unprognostic (2.98e-2)" "unprognostic (2.51e-1)" "unprognostic (1.40e-1)" "unprognostic (1.74e-2)" "unprognostic (5.33e-2)" "unprognostic (8.03e-3)" "unprognostic (7.71e-8)" "unprognostic (2.50e-2)" "unprognostic (1.52e-1)" "unprognostic (1.95e-1)" "unprognostic (1.53e-1)" 1.5 0.3 0.8 0.5 0.4 1.3 0.7 0.9 1.0 0.6 0.8 0.2 0.1 0.6 0.2 0.4 0.4 1.7 74.6 0.3 0.6 0.1 0.3 2.0 1.5 1.2 1.1 1.0 5.8 0.1 0.0 1.2 1.4 0.3 0.2 1.1 0.1 0.2 17.1 0.5 0.2 0.2 1.6 0.7 0.2 1.5 1.0 1.5 0.3 3.5 1.1 0.3 0.1 1.8 0.1 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.1 4.6 0.3 3.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 2.6 0.1 6.9 0.2 0.0 0.0 1.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.1 0.0 0.1 0.2 2.4 0.4 0.5 0.1 3.6 1.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.7 0.2 0.3 0.0 0.2 0.1 0.2 0.0 4.3 0.1 6.1 0.2 0.3 0.4 0.4 0.0 0.2 0.3 0.0 0.2 7.3 2.2 1.5 0.0 8.1 6.5 5.1 0.3 1.2 0.0 0.0 15.0 0.4 0.8 0.4 0.9 1.0 0.3 0.6 1.2 1.1 1.4 1.6 1.0 1.8 4.5 6.4 29.5 5.5 11.0 0.1 0.0 0.0 0.6 28.1 0.2 0.3 118.2 27.1 0.6 0.0 0.0 0.0 2.8 0.1 0.0 4.6 37.3 0.2 1.1 6.7 0.0 0.4 3.6 1.3 0.2 2.9 0.0 1.1 6.3 0.0 0.4 0.3 0.0 6.7 3.1 0.1 0.0 1.0 1.0 16.8 1.2 3.9 1.8 8.4 0.1 5.5 1.0 0.5 0.8 0.2 0.0 1.9 2.6 0.0 0.2 0.1 1.5 0.6 6.6 2.8 5.4 0.1 1.1 0.0 0.1 0.0 10.3 1.1 0.2 0.2 CCDC151 "MGC20983, ODA10" ENSG00000198003 "Coiled-coil domain containing 151" A5D8V7 19 11420604-11435782 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.0;parathyroid gland: 9.8;testis: 10.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Kupffer cells: 51.6;Muller glia cells: 58.9;Respiratory ciliated cells: 29.6;Spermatocytes: 22.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.0;T-47d: 4.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA054626 Enhanced NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 5: Muller glia cells - Visual perception" "HPA054626: AB_2682547" "unprognostic (1.50e-1)" "unprognostic (6.59e-2)" "unprognostic (2.05e-3)" "unprognostic (4.41e-3)" "unprognostic (1.35e-2)" "unprognostic (6.30e-2)" "unprognostic (4.41e-3)" "unprognostic (2.32e-2)" "unprognostic (2.22e-1)" "unprognostic (5.09e-2)" "unprognostic (6.76e-4)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (4.27e-2)" "unprognostic (1.85e-1)" "unprognostic (2.35e-1)" "unprognostic (2.05e-1)" 0.4 2.8 4.6 0.0 4.6 0.0 0.4 4.7 6.5 1.6 15.0 0.3 0.0 0.6 0.3 0.2 8.5 0.0 1.9 5.0 4.7 3.5 0.7 2.3 0.0 6.4 6.8 0.6 0.4 9.8 7.0 0.4 5.7 0.8 0.0 0.9 1.7 0.5 0.1 0.5 0.2 0.0 5.2 2.6 0.4 10.4 4.6 0.0 2.9 0.0 0.0 0.3 0.8 4.9 0.2 0.0 0.6 0.2 0.1 0.2 0.5 0.2 0.1 0.3 0.4 0.0 0.0 0.1 0.2 0.1 1.2 0.1 0.5 0.2 0.0 0.5 0.5 0.2 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.5 0.1 0.4 0.0 0.1 0.2 0.1 1.0 0.2 0.0 0.7 0.3 0.0 2.0 1.3 0.6 0.1 0.1 0.1 4.8 0.2 0.0 0.8 0.1 1.7 0.0 1.7 1.4 0.1 1.8 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.6 4.6 4.7 6.5 5.0 4.7 6.4 6.8 5.7 5.2 4.6 4.9 1.1 0.0 0.0 6.5 5.7 0.9 0.7 1.0 0.6 1.1 0.8 1.3 2.2 1.5 2.6 12.9 0.0 0.5 0.0 0.0 29.4 0.2 12.4 20.3 4.2 2.9 0.0 0.0 2.3 0.2 0.5 3.8 0.5 1.1 4.5 1.6 14.3 1.2 4.7 1.7 1.7 0.5 2.0 51.6 1.7 14.5 2.8 7.8 7.2 1.0 2.6 58.9 0.0 1.0 0.8 0.1 0.0 0.7 0.8 0.1 0.1 1.1 29.6 3.2 6.6 15.2 6.8 22.7 6.6 0.1 0.4 1.2 1.5 1.0 0.0 0.5 CCDC189 "C16orf93, MGC104706" ENSG00000196118 "Coiled-coil domain containing 189" A1A4V9 16 30757423-30762221 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 18.4" "Group enriched" "Detected in many" 4 "Early spermatids: 208.2;Late spermatids: 318.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041806, HPA046289, HPA075094" Approved Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA041806: AB_2677684, HPA046289: AB_2679615, HPA075094: " "unprognostic (5.84e-2)" "unprognostic (3.95e-3)" "unprognostic (1.86e-2)" "unprognostic (1.45e-4)" "unprognostic (3.60e-2)" "unprognostic (5.41e-3)" "unprognostic (7.76e-5)" "unprognostic (1.66e-2)" "unprognostic (1.82e-2)" "unprognostic (5.11e-3)" "unprognostic (2.15e-4)" "unprognostic (1.22e-3)" "unprognostic (1.06e-7)" "unprognostic (1.75e-3)" "unprognostic (2.14e-1)" "unprognostic (6.63e-2)" "unprognostic (3.41e-2)" 1.1 5.2 6.7 1.6 6.8 7.9 2.7 5.8 8.7 3.0 12.2 1.9 1.1 1.8 4.3 1.7 10.4 1.6 0.7 7.4 6.7 6.5 1.3 3.9 1.1 6.9 8.1 2.1 3.7 2.3 12.6 0.6 8.9 4.1 1.7 3.5 3.3 1.9 0.3 1.2 1.8 0.7 6.8 2.1 2.0 18.4 6.7 1.7 6.5 0.1 2.1 1.4 1.2 5.9 7.1 5.2 1.1 5.3 1.5 1.7 0.3 2.6 1.2 2.8 2.1 0.3 5.0 0.2 4.3 2.1 1.4 8.2 0.8 4.3 1.2 0.7 9.8 1.9 10.1 2.5 0.3 2.4 1.8 0.4 0.4 5.1 4.4 4.0 2.2 1.8 2.6 1.2 2.2 4.3 2.9 4.6 1.9 2.2 2.5 2.8 1.6 5.2 6.2 0.0 4.2 1.5 3.0 7.7 1.6 1.3 7.5 3.6 1.8 1.3 1.0 2.2 2.6 3.6 2.2 2.1 8.3 7.3 0.4 1.9 1.1 6.0 0.1 1.3 0.9 1.0 0.0 0.2 1.8 0.1 0.0 0.2 0.4 1.9 3.3 12.2 0.1 0.8 6.7 6.8 5.8 8.7 7.4 6.7 6.9 8.1 8.9 6.8 6.7 5.9 0.6 0.0 3.1 0.0 4.3 0.0 4.0 0.0 4.6 1.0 6.8 4.2 0.0 0.0 3.7 7.3 4.2 2.9 16.1 1.6 5.9 3.9 208.2 42.9 2.3 1.4 2.4 14.3 0.0 3.0 1.1 3.5 12.8 4.0 1.3 2.3 0.7 1.1 4.5 0.0 0.0 2.0 0.0 2.2 0.0 318.0 7.5 5.4 0.0 0.0 4.8 3.7 1.0 0.0 0.0 1.9 1.6 4.9 11.9 3.6 1.0 8.6 49.6 15.0 0.0 1.0 1.5 52.7 15.7 2.0 0.0 2.5 2.1 7.0 1.8 3.7 CCDC194 ENSG00000269720 "Coiled-coil domain containing 194" A0A1B0GVG4 19 17390509-17394158 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "brain: 3.8;ovary: 2.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "ovarian cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 52: Non-specific - Transcription" "unprognostic (1.50e-3)" "unprognostic (1.37e-1)" "unprognostic (1.87e-4)" "unprognostic (2.75e-3)" "unprognostic (1.41e-1)" "unprognostic (1.28e-2)" "unprognostic (3.09e-1)" "unprognostic (9.87e-2)" "unprognostic (3.07e-1)" "unprognostic (5.84e-2)" "unprognostic (1.23e-1)" "unprognostic (2.64e-2)" "unprognostic (5.22e-14)" "unprognostic (1.04e-1)" "unprognostic (6.70e-3)" "unprognostic (2.60e-1)" "unprognostic (1.86e-2)" 0.2 0.3 0.9 0.0 0.7 0.0 0.1 0.4 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.3 0.1 0.1 0.1 0.0 1.0 0.5 2.2 0.0 0.0 0.1 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.2 0.2 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.4 3.8 0.4 0.3 1.0 0.5 0.8 1.2 1.1 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 CCDC3 DKFZp761F241 ENSG00000151468 "Coiled-coil domain containing 3" Q9BQI4 10 12896625-13099652 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 132.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 50.1;Excitatory neurons: 100.2;Inhibitory neurons: 41.3;Peritubular cells: 60.5;Smooth muscle cells: 119.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 10.4;HAP1: 19.1;HDLM-2: 32.4;hTERT-RPE1: 14.8;U-2 OS: 20.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 20.8" HPA062425 Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA062425: AB_2684759" "unprognostic (2.26e-1)" "unprognostic (6.65e-3)" "unprognostic (1.70e-1)" "unprognostic (4.30e-3)" "unprognostic (1.72e-1)" "unprognostic (5.08e-2)" "unprognostic (3.11e-2)" "unprognostic (2.99e-2)" "unprognostic (5.56e-3)" "unprognostic (5.41e-2)" "unprognostic (4.25e-3)" "unprognostic (2.22e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.54e-2)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" "unprognostic (3.88e-2)" 91.8 11.0 32.9 5.9 35.2 0.1 37.2 17.9 40.2 48.1 17.8 10.1 6.6 25.0 41.3 60.4 56.7 70.7 21.9 37.1 20.1 19.0 20.6 21.0 12.4 18.6 19.1 86.2 6.5 4.9 10.2 22.2 19.6 35.2 7.4 1.6 7.1 22.0 30.7 132.2 14.3 24.2 19.8 24.7 13.1 11.6 21.7 42.0 20.0 13.3 4.2 23.2 27.4 30.5 0.0 0.2 1.7 9.4 0.0 0.0 0.1 0.0 0.0 0.7 0.0 2.5 0.0 0.0 0.7 0.0 10.4 1.9 19.1 3.6 0.6 32.4 8.1 0.0 0.2 0.0 0.7 0.0 0.0 2.3 2.3 0.4 0.0 14.8 0.9 0.8 0.0 0.2 1.0 0.2 0.0 5.4 1.5 0.0 0.1 0.0 4.1 0.3 0.0 0.0 3.6 1.6 7.0 1.0 0.0 4.4 0.0 0.0 0.0 0.0 20.0 1.2 0.3 0.0 0.0 0.0 0.1 0.0 6.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.9 35.2 17.9 40.2 37.1 20.1 18.6 19.1 19.6 19.8 21.7 30.5 12.4 0.0 0.0 10.1 0.1 50.1 6.4 26.3 13.6 1.2 0.9 4.7 7.9 1.5 2.1 0.0 0.0 0.3 1.3 0.1 1.9 0.0 0.2 0.1 0.7 27.2 0.0 0.0 100.2 0.0 0.2 16.0 0.5 0.4 0.0 16.4 8.2 0.2 0.3 0.0 41.3 0.1 0.0 0.0 6.4 1.5 22.4 0.6 14.2 3.7 0.0 0.3 0.0 22.6 23.2 0.1 2.5 60.5 0.0 3.0 0.3 0.4 1.1 2.1 32.9 7.9 119.4 0.0 5.7 2.1 37.2 0.3 1.0 6.0 0.3 1.3 CCDC47 GK001 ENSG00000108588 "Coiled-coil domain containing 47" Q96A33 17 63745255-63776351 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029674, HPA072573, HPA075958" Approved Enhanced "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA029674: AB_10602703, HPA072573: AB_2686535, HPA075958: " "unprognostic (6.33e-2)" "unprognostic (3.26e-2)" "prognostic favorable (2.17e-4)" "unprognostic (1.38e-1)" "unprognostic (3.54e-1)" "unprognostic (1.47e-2)" "unprognostic (1.53e-2)" "unprognostic (9.08e-2)" "unprognostic (1.57e-1)" "unprognostic (3.68e-1)" "unprognostic (2.73e-1)" "unprognostic (1.26e-1)" "unprognostic (8.35e-2)" "unprognostic (1.88e-1)" "unprognostic (6.43e-2)" "unprognostic (7.46e-2)" "unprognostic (1.16e-1)" 57.9 67.3 24.3 42.5 33.6 29.0 57.1 28.8 39.2 47.7 46.9 83.4 87.1 39.1 53.7 52.6 43.9 48.2 65.5 29.3 27.9 72.0 102.2 52.7 33.5 28.8 27.4 35.3 59.8 84.6 21.9 54.8 29.9 60.2 80.6 46.9 62.4 52.0 115.3 52.2 78.2 42.1 30.1 35.6 78.5 32.1 26.0 29.9 62.0 83.7 40.5 58.5 29.3 34.3 143.3 133.8 81.4 71.9 112.4 74.0 158.0 141.9 92.6 96.1 112.4 118.7 127.0 112.9 74.3 100.9 110.8 114.3 99.3 88.1 168.9 39.4 101.2 160.9 106.4 117.3 107.6 129.9 81.3 78.5 121.3 132.4 113.2 67.9 81.3 55.3 183.5 95.5 79.4 116.1 100.5 48.1 70.8 179.4 134.0 92.2 157.9 154.6 115.3 161.1 74.2 101.5 95.2 242.8 120.3 103.0 159.8 70.4 104.0 177.6 112.9 130.6 166.0 93.9 119.9 112.8 103.9 81.4 147.3 53.2 59.7 75.6 40.7 61.5 47.9 38.4 39.8 37.9 82.5 31.7 41.1 36.2 47.6 43.4 65.9 54.7 49.0 52.0 24.3 33.6 28.8 39.2 29.3 27.9 28.8 27.4 29.9 30.1 26.0 34.3 96.9 144.2 122.2 16.3 46.6 100.8 108.5 95.9 98.4 40.9 65.9 53.6 129.0 72.9 128.3 60.7 14.6 111.1 59.0 99.8 9.8 115.3 17.9 80.3 73.9 83.9 52.2 76.6 26.2 105.1 98.3 85.3 65.7 126.0 45.5 31.2 68.2 96.3 57.5 57.2 25.9 95.1 83.4 56.9 58.3 11.5 47.8 60.7 39.2 13.1 52.9 55.3 25.7 22.6 25.5 92.0 62.6 56.1 56.0 89.6 87.5 32.6 83.0 27.9 72.3 117.2 92.1 82.0 44.7 90.1 90.8 144.1 42.7 53.0 110.5 83.3 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCDC85A KIAA1912 ENSG00000055813 "Coiled-coil domain containing 85A" Q96PX6 2 56183990-56386172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3" "Cell type enhanced" "Detected in some" "Adipocytes: 57.7;Excitatory neurons: 228.7;Inhibitory neurons: 160.5;Microglial cells: 60.0" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 45.9;fHDF/TERT166: 74.5;U-266/70: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043106, HPA057020" Uncertain "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043106: AB_10794770, HPA057020: AB_2683311" "unprognostic (2.29e-1)" "unprognostic (1.28e-1)" "unprognostic (6.87e-2)" "unprognostic (3.66e-2)" "unprognostic (7.87e-2)" "unprognostic (7.62e-2)" "unprognostic (3.07e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (1.53e-2)" "unprognostic (2.57e-1)" "unprognostic (6.55e-5)" "unprognostic (3.28e-2)" "unprognostic (1.00e-1)" "unprognostic (2.88e-2)" "unprognostic (1.83e-2)" 12.5 0.6 5.4 0.6 7.4 0.0 3.5 1.2 8.0 2.5 0.0 0.7 0.3 6.3 0.8 0.7 2.1 1.2 4.5 6.9 7.2 1.0 0.1 5.5 0.5 17.3 6.5 0.5 0.7 1.3 0.2 10.0 7.0 2.0 0.7 4.0 1.2 2.7 5.4 1.7 0.4 4.7 11.8 0.7 0.5 0.4 5.1 0.6 9.1 7.5 0.6 0.7 0.7 15.2 0.0 0.8 0.1 0.0 13.9 0.8 0.0 11.6 1.1 9.8 0.9 0.0 0.1 45.9 1.7 74.5 0.0 2.0 0.0 0.0 5.6 0.0 0.3 0.0 0.6 0.0 0.7 0.0 0.1 3.3 0.3 0.0 1.2 5.5 9.7 0.0 0.0 6.1 1.3 0.2 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 1.7 1.3 0.0 0.3 0.1 0.0 2.1 5.3 0.0 15.3 7.9 2.3 0.1 0.9 32.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 7.4 1.2 8.0 6.9 7.2 17.3 6.5 7.0 11.8 5.1 15.2 57.7 25.6 0.6 15.3 0.8 3.3 0.5 0.0 0.0 7.8 0.6 0.5 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 0.3 3.6 0.2 1.9 14.8 1.2 0.0 228.7 0.4 0.1 3.7 0.0 0.5 0.0 0.2 8.6 0.0 2.3 0.0 160.5 0.2 0.0 0.3 2.0 11.9 0.3 0.3 5.4 60.0 0.0 0.7 0.0 33.7 7.2 0.7 0.1 0.0 0.1 0.3 0.0 0.3 0.0 1.5 0.0 10.0 2.7 0.2 0.8 0.1 1.3 0.1 0.1 3.6 0.9 0.3 CCDC88B "BRLZ, CCDC88, FLJ00354, FLJ37970, GIPIE, HkRP3" ENSG00000168071 "Coiled-coil domain containing 88B" A6NC98 11 64340204-64357534 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.6;lymphoid tissue: 86.1" "Cell type enhanced" "Detected in many" "NK-cells: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 21.7;HMC-1: 83.3;Karpas-707: 22.0;THP-1: 34.5;U-937: 25.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA026652 Approved Supported Nucleoplasm,Centrosome,Cytosol "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Centrosome, Cytosol" Nucleoplasm "HPA026652: AB_1846168" "unprognostic (1.18e-2)" "unprognostic (3.33e-3)" "unprognostic (3.65e-1)" "unprognostic (1.58e-2)" "unprognostic (2.36e-1)" "prognostic favorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (1.55e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (7.32e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.77e-2)" "unprognostic (7.38e-2)" "unprognostic (1.90e-1)" "unprognostic (2.83e-2)" 8.5 6.7 14.9 15.1 15.1 47.6 5.3 20.1 21.6 5.6 15.3 17.8 4.0 3.5 0.3 12.9 6.5 8.5 5.5 15.3 15.0 6.5 7.3 21.1 28.6 17.2 15.5 3.1 4.1 0.9 4.5 1.7 17.5 7.8 3.6 1.4 14.4 2.5 1.2 4.5 34.1 1.2 15.4 86.1 8.9 17.4 15.4 17.4 5.4 0.8 13.8 8.3 7.7 15.9 0.3 1.3 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.0 3.4 19.7 2.9 1.1 0.5 1.6 0.1 0.6 0.0 21.7 0.0 15.0 4.6 1.1 0.8 9.4 83.3 0.0 0.0 0.2 0.0 1.3 0.5 6.3 0.5 22.0 0.7 0.9 12.7 7.7 0.7 3.7 0.5 11.9 0.3 18.5 0.3 0.3 4.8 0.0 0.0 0.5 1.1 0.1 2.6 34.5 0.0 0.0 0.7 0.1 0.2 4.7 1.5 15.8 1.0 25.3 0.4 2.9 4.6 6.7 3.5 3.6 1.0 1.6 2.0 2.9 1.6 2.0 1.8 2.2 9.2 6.5 2.5 2.7 0.6 1.3 14.9 15.1 20.1 21.6 15.3 15.0 17.2 15.5 17.5 15.4 15.4 15.9 3.3 0.0 10.7 5.2 30.3 2.7 4.5 10.5 0.6 45.2 5.7 4.8 13.5 4.3 9.9 9.2 0.0 2.9 34.9 46.0 0.0 12.8 11.1 8.7 2.6 4.4 18.0 7.0 2.6 28.9 5.8 3.1 51.0 6.8 26.6 2.2 6.1 10.4 14.5 0.0 2.0 24.4 8.2 26.0 26.6 15.8 1.5 27.3 5.4 12.2 35.0 15.4 64.9 2.0 0.6 35.0 33.2 0.7 24.9 2.9 36.1 3.2 22.7 4.7 0.0 2.8 2.8 13.7 8.7 2.0 1.6 1.4 31.7 10.0 32.4 15.7 CCER2 ENSG00000262484 "Coiled-coil glutamate rich protein 2" I3L3R5 19 38908980-38912158 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 8 "Melanocytes: 617.2" "Group enriched" "Detected in many" 5 "glioma: 5.1;testis cancer: 1.9;urothelial cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.4;THP-1: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069716 Uncertain "Secreted - unknown location" NA NA 8800 "Cluster 27: Brain & Skin - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA069716: AB_2686183" "unprognostic (6.58e-2)" "unprognostic (2.24e-2)" "unprognostic (5.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (2.76e-3)" "unprognostic (3.88e-2)" "unprognostic (2.16e-1)" "unprognostic (5.97e-2)" "unprognostic (1.45e-1)" "unprognostic (4.08e-3)" "unprognostic (3.82e-2)" "unprognostic (1.01e-9)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.32e-4)" 0.5 0.6 2.2 0.2 2.4 0.7 0.8 2.3 3.4 1.2 1.8 0.9 0.3 0.7 0.3 1.2 1.1 0.1 0.9 2.3 2.2 1.8 2.9 0.5 0.3 2.9 2.2 0.7 0.5 0.2 2.5 0.1 2.4 1.4 0.1 1.0 0.9 0.2 2.3 4.2 0.9 0.1 2.1 1.1 0.6 4.9 2.2 0.4 1.2 0.0 0.1 0.9 0.8 2.4 0.1 1.4 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.5 1.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.0 0.6 0.5 0.1 0.2 0.1 0.0 0.0 0.0 0.9 0.2 0.9 0.0 0.9 0.2 0.4 0.3 0.0 0.2 0.7 0.1 0.2 0.1 0.6 0.4 0.2 0.1 0.1 0.0 0.1 1.0 1.4 0.0 0.0 0.7 0.0 0.0 0.6 0.5 0.2 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 2.3 3.4 2.3 2.2 2.9 2.2 2.4 2.1 2.2 2.4 0.1 3.2 0.0 3.9 0.1 76.9 0.1 0.1 0.0 2.5 0.4 0.5 0.4 1.5 0.1 1.8 4.2 0.4 0.4 0.3 0.0 0.0 1.4 0.3 0.2 0.6 1.2 0.4 2.3 0.0 0.1 0.8 0.0 0.5 0.0 0.3 0.0 0.6 0.2 0.0 3.3 0.2 0.0 0.3 7.2 4.9 0.3 0.2 617.2 0.0 0.0 1.3 0.0 3.5 2.2 0.1 0.2 0.0 0.0 0.1 0.2 0.2 0.4 3.8 0.0 0.4 0.7 1.1 2.1 0.0 3.0 0.3 0.4 0.2 0.6 0.1 CCK ENSG00000187094 Cholecystokinin P06307 3 42257825-42266185 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 317.9;choroid plexus: 89.5;intestine: 115.7" "Cell type enhanced" "Detected in many" "Astrocytes: 40.1;Excitatory neurons: 154.8;Fibroblasts: 42.5;Inhibitory neurons: 157.7;Melanocytes: 40.9;Oligodendrocytes: 40.9;Prostatic glandular cells: 63.8" "Group enriched" "Detected in many" 5 "glioma: 4.0;pancreatic cancer: 1.8;prostate cancer: 3.5;stomach cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "OE19: 236.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 74.4" "HPA045039, HPA069515" Enhanced Supported "Secreted to blood" NA NA 43700000 "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA045039: , HPA069515: AB_2732135" "unprognostic (3.36e-1)" "unprognostic (1.58e-1)" "unprognostic (1.92e-1)" "unprognostic (1.40e-3)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "unprognostic (2.39e-3)" "unprognostic (1.97e-2)" "unprognostic (3.91e-1)" "unprognostic (8.77e-2)" "unprognostic (1.35e-1)" "unprognostic (2.42e-1)" "unprognostic (1.37e-1)" "unprognostic (5.10e-2)" 0.2 0.9 134.4 0.5 202.6 0.0 0.2 85.8 317.9 0.0 89.5 4.4 115.7 0.0 0.0 0.3 0.5 0.0 0.1 160.1 96.9 1.2 0.4 3.4 0.0 99.9 103.4 0.1 0.4 0.0 18.4 1.1 94.5 19.5 0.1 4.4 0.2 0.2 0.2 0.4 17.0 0.2 93.9 0.0 2.1 2.3 123.9 0.2 0.1 0.0 0.0 0.1 0.1 143.7 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 9.7 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 236.5 0.1 0.0 0.0 1.1 25.0 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 134.4 202.6 85.8 317.9 160.1 96.9 99.9 103.4 94.5 93.9 123.9 143.7 0.4 0.0 0.0 40.1 0.2 5.7 1.3 0.3 0.6 6.8 1.3 1.9 0.3 0.0 0.2 5.5 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.1 2.5 0.0 0.0 154.8 0.4 0.1 42.5 5.1 0.4 0.0 0.0 1.4 0.0 0.1 0.0 157.7 11.4 2.0 0.3 3.0 0.3 0.0 0.6 40.9 34.7 0.0 36.7 0.0 34.7 40.9 0.7 0.0 0.0 0.0 63.8 0.6 0.1 0.0 3.5 0.0 0.8 6.4 0.1 1.7 0.0 1.3 10.5 0.0 0.0 0.5 8.7 CCL1 "I-309, P500, SCYA1, SISe, TCA3" ENSG00000108702 "C-C motif chemokine ligand 1" P22362 17 34360328-34363233 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 2.2;lymphoid tissue: 1.2" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;granulocytes: 8.9;Late spermatids: 1.6;T-cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 38 "HMC-1: 702.6" HPA049861 Uncertain "Secreted to blood" NA NA 84400 "Cluster 25: Monocytes - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA049861: AB_2680919" "unprognostic (6.52e-2)" "unprognostic (4.81e-3)" "unprognostic (5.84e-2)" "unprognostic (5.01e-1)" "unprognostic (6.04e-1)" "unprognostic (2.71e-1)" "unprognostic (1.37e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 702.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.4 0.8 0.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 CCL11 "eotaxin, MGC22554, SCYA11" ENSG00000172156 "C-C motif chemokine ligand 11" P51671 17 34285742-34288334 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.7;lymphoid tissue: 31.4;stomach 1: 35.1;urinary bladder: 41.0" "Cell type enriched" "Detected in some" 15 "Fibroblasts: 38.9" "Cancer enhanced" "Detected in many" "stomach cancer: 12.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "BJ hTERT+: 9.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 88500 "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.61e-2)" "unprognostic (1.45e-1)" "prognostic favorable (8.70e-4)" "unprognostic (8.18e-2)" "prognostic favorable (1.99e-4)" "unprognostic (9.91e-2)" "unprognostic (8.09e-2)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (1.45e-1)" "unprognostic (9.64e-8)" "unprognostic (2.66e-2)" "unprognostic (1.05e-3)" "unprognostic (1.61e-1)" "unprognostic (2.72e-2)" 3.8 0.8 0.0 31.4 0.0 0.0 0.2 0.0 0.0 3.6 0.0 41.7 33.2 1.7 0.0 12.4 0.7 4.8 16.7 0.0 0.0 5.8 0.6 9.1 0.0 0.0 0.0 0.3 2.8 1.7 1.0 0.0 0.0 2.6 14.7 0.0 0.1 0.9 0.0 0.0 35.8 20.5 0.0 2.8 35.1 0.0 0.0 0.3 0.0 0.0 0.7 41.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 9.7 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.1 1.9 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.0 0.1 CCL13 "CKb10, MCP-4, MGC17134, NCC-1, SCYA13, SCYL1" ENSG00000181374 "C-C motif chemokine ligand 13" Q99616 17 34356480-34358610 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.4;urinary bladder: 30.4" "Cell type enhanced" "Detected in some" "Hofbauer cells: 48.7;Langerhans cells: 81.2;Melanocytes: 17.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.8;BJ hTERT+: 1.7;BJ hTERT+ SV40 Large T+ RasG12V: 1.0;HMC-1: 1.3;HSkMC: 1.7" "Secreted to blood" NA NA 336000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "unprognostic (2.22e-2)" "unprognostic (3.56e-2)" "unprognostic (8.41e-3)" "unprognostic (1.49e-3)" "unprognostic (4.43e-2)" "unprognostic (1.58e-1)" "unprognostic (7.58e-2)" "unprognostic (8.49e-2)" "unprognostic (1.18e-1)" "unprognostic (2.83e-2)" "unprognostic (1.35e-2)" "unprognostic (5.98e-2)" "unprognostic (8.63e-8)" "unprognostic (2.26e-1)" "unprognostic (2.57e-1)" "unprognostic (1.37e-1)" "unprognostic (1.71e-2)" 24.0 4.5 0.0 7.0 0.0 0.3 18.4 0.0 0.5 3.2 0.0 30.4 21.3 0.6 0.3 11.9 4.4 2.7 11.8 0.0 0.0 1.7 0.2 22.5 3.2 0.0 0.0 0.3 0.7 1.6 0.1 9.7 0.0 1.6 25.1 0.0 2.6 0.8 0.6 4.5 27.0 9.0 0.0 0.1 2.9 2.4 0.0 8.7 1.8 5.8 1.8 30.4 3.2 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.2 1.7 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.2 0.0 0.0 0.0 8.8 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.4 7.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 81.2 0.3 0.0 6.6 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.0 0.0 0.1 4.7 0.3 1.0 0.0 0.0 0.1 CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 1156.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "HUVEC TERT2: 92.1" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" 411.9 102.7 0.4 6.4 0.3 3.3 400.7 0.2 1.7 192.0 2.8 66.6 2.9 198.0 59.3 62.0 233.5 69.3 98.6 0.3 0.3 69.2 82.6 66.4 49.0 0.5 0.3 44.1 22.6 12.4 39.5 0.9 0.7 97.4 9.8 0.0 61.9 49.5 55.9 93.3 50.5 94.3 0.4 632.7 67.5 16.0 0.4 34.4 123.9 24.5 28.2 116.8 177.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.7 0.3 0.3 0.5 0.3 0.7 0.4 0.4 0.3 136.5 0.0 8.2 0.0 2.2 1.9 0.1 0.0 3.4 0.0 0.6 1.1 0.2 18.6 0.6 0.0 0.0 0.0 0.1 2.0 0.0 0.0 24.2 0.4 0.3 203.8 0.0 26.7 0.0 0.0 0.0 9.4 0.0 0.2 1.3 0.0 1156.5 11.0 0.3 0.0 0.0 1.0 0.0 58.8 3.1 63.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 2.3 1.1 2.6 0.0 0.0 0.3 2.3 0.0 0.0 2.0 1.4 0.0 1.8 0.1 0.6 0.2 CCL15 "HCC-2, HMRP-2B, Lkn-1, MIP-1d, MIP-5, NCC-3, SCYA15, SCYL3" ENSG00000275718 "C-C motif chemokine ligand 15" Q16663 17 35996440-36001553 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 83.0;liver: 31.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 262.6;Intestinal goblet cells: 208.3;Paneth cells: 380.6;Proximal enterocytes: 461.4;Undifferentiated cells: 138.2" "Cancer enhanced" "Detected in many" "liver cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Hep G2: 35.4;OE19: 28.7" HPA058608 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 3270000 11000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" Vesicles "HPA058608: AB_2683776" "unprognostic (1.26e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-2)" "unprognostic (1.40e-1)" "unprognostic (8.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-1)" "unprognostic (2.41e-2)" "unprognostic (1.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.15e-1)" "unprognostic (1.07e-2)" "prognostic favorable (3.02e-4)" 0.2 0.4 0.1 7.8 0.1 0.1 0.4 0.1 0.3 0.3 0.0 59.7 37.6 0.1 0.0 0.2 9.6 9.2 0.0 0.1 0.1 10.0 31.6 2.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 83.0 0.0 0.1 0.1 0.0 0.1 62.0 1.4 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.3 4.9 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 28.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.3 0.5 0.0 0.5 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 0.1 7.2 5.0 0.0 0.0 0.0 0.0 262.6 0.0 0.0 0.0 12.2 0.1 0.7 71.8 0.0 0.0 0.7 0.0 0.0 0.0 0.1 8.9 0.0 2.5 40.2 0.1 0.0 0.0 208.3 2.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 380.6 0.0 0.0 0.0 461.4 61.3 76.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 138.2 0.2 CCL16 "CKb12, HCC-4, LCC-1, LEC, LMC, Mtn-1, NCC-4, SCYA16, SCYL4" ENSG00000275152 "C-C motif chemokine ligand 16" O15467 17 35976493-35981497 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "liver: 120.3" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 262.0" "Cancer enriched" "Detected in single" 154 "liver cancer: 49.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "Hep G2: 10.1" "Low region specificity" "Detected in some" "Secreted to blood" NA NA 2780000 23000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (3.85e-1)" "unprognostic (4.71e-1)" "unprognostic (1.49e-1)" "unprognostic (3.75e-2)" "unprognostic (2.72e-1)" "unprognostic (4.58e-2)" "unprognostic (2.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" "unprognostic (1.91e-2)" "unprognostic (3.57e-1)" "unprognostic (1.40e-3)" "unprognostic (1.66e-2)" "unprognostic (2.32e-1)" "unprognostic (1.09e-1)" "unprognostic (4.08e-2)" 0.7 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.2 0.1 0.5 0.0 0.2 0.5 0.2 0.2 0.0 0.0 0.3 120.3 0.3 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.2 0.0 2.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 262.0 0.0 0.0 0.0 0.2 0.0 4.1 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 CCL17 "ABCD-2, SCYA17, TARC" ENSG00000102970 "C-C motif chemokine ligand 17" Q92583 16 57404767-57416063 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 21.1" "Cell type enriched" "Detected in some" 55 "monocytes: 12161.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 640 "HDLM-2: 2395.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "basal ganglia: 4.3" CAB002583 Uncertain "Secreted to blood" NA NA 248000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB002583: AB_564022" "unprognostic (4.62e-3)" "prognostic favorable (1.91e-5)" "unprognostic (5.83e-2)" "unprognostic (3.52e-4)" "unprognostic (4.51e-2)" "unprognostic (1.78e-3)" "unprognostic (4.44e-1)" "unprognostic (3.41e-2)" "unprognostic (6.36e-2)" "unprognostic (4.28e-2)" "unprognostic (4.11e-1)" "unprognostic (2.91e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-1)" "unprognostic (7.72e-3)" "unprognostic (4.14e-3)" "prognostic favorable (5.80e-4)" 1.2 0.1 0.1 8.3 0.1 0.0 1.9 0.1 0.4 1.4 0.0 1.5 0.1 0.0 0.0 3.1 0.6 2.9 1.3 0.2 0.0 0.6 0.3 4.5 8.4 0.1 0.0 0.2 0.5 0.1 0.0 0.1 0.1 0.3 2.7 0.0 2.5 0.2 0.1 2.4 3.7 2.6 0.0 0.8 0.7 0.5 0.1 21.1 0.8 0.2 5.7 3.4 0.9 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 3.3 0.0 0.0 0.0 2395.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.0 3.7 0.2 0.0 0.0 2.9 1.5 0.1 0.1 2.0 0.0 0.0 0.1 0.0 1.0 0.0 1.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.3 0.0 5.1 0.0 0.4 10.8 0.1 3.4 0.0 0.0 1.1 1.5 0.0 0.0 3.8 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.3 0.1 0.0 0.6 0.0 0.0 0.2 37.4 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 2.0 1.0 217.9 0.3 0.0 48.7 0.0 0.0 12161.5 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.1 0.0 0.4 2.1 0.0 0.0 0.0 12.0 0.0 0.5 0.0 2.7 0.0 0.4 0.0 0.0 0.7 CCL18 "AMAC-1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18" ENSG00000275385 "C-C motif chemokine ligand 18" P55774 17 36064272-36072032 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lung: 48.7" "Group enriched" "Detected in some" 5 "Hofbauer cells: 189.1;Langerhans cells: 104.3;Macrophages: 153.1" "Cancer enhanced" "Detected in all" "lung cancer: 76.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 55500000 6400000 "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "unprognostic (8.91e-2)" "unprognostic (2.96e-2)" "unprognostic (5.71e-2)" "unprognostic (9.64e-2)" "unprognostic (1.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.04e-1)" "unprognostic (2.96e-1)" "unprognostic (2.50e-1)" "unprognostic (3.11e-2)" "unprognostic (1.21e-2)" "unprognostic (4.06e-2)" "unprognostic (2.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.68e-1)" "unprognostic (3.63e-1)" "unprognostic (4.87e-2)" 9.7 0.3 0.0 2.5 0.0 0.2 1.6 0.0 0.0 0.0 0.0 2.0 3.9 0.1 0.0 0.9 0.4 0.0 1.6 0.0 0.0 0.2 0.3 48.7 7.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.7 0.0 2.5 0.0 0.0 0.9 9.2 1.5 0.0 4.0 0.2 0.5 0.1 6.1 1.1 0.0 5.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 25.4 0.0 1.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 13.6 0.0 0.0 0.5 4.2 0.0 0.0 0.0 24.5 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 5.1 0.0 0.4 0.7 189.1 0.0 0.0 0.0 0.0 4.2 104.3 5.3 0.0 153.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.4 0.9 0.0 0.1 0.1 3.4 1.6 2.9 0.0 0.0 0.0 CCL19 "CKb11, ELC, exodus-3, MIP-3b, SCYA19" ENSG00000172724 "C-C motif chemokine ligand 19" Q99731 9 34689570-34691276 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 632.5" "Group enriched" "Detected in some" 12 "Basal keratinocytes: 74.7;Basal respiratory cells: 56.9;Fibroblasts: 59.6;Langerhans cells: 111.9;Melanocytes: 92.5;monocytes: 107.1;Smooth muscle cells: 150.9;Suprabasal keratinocytes: 54.0" "Cancer enhanced" "Detected in all" "testis cancer: 118.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.0;HDLM-2: 3.2;TIME: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067758 Enhanced "Secreted to blood" NA NA 195000 63000 "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA067758: AB_2685897" "prognostic favorable (2.88e-5)" "prognostic favorable (9.91e-6)" "unprognostic (8.25e-3)" "unprognostic (1.16e-1)" "unprognostic (1.65e-1)" "unprognostic (1.67e-2)" "unprognostic (1.30e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (8.36e-3)" "unprognostic (8.31e-2)" "unprognostic (2.43e-1)" "prognostic unfavorable (8.63e-7)" "unprognostic (7.98e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-1)" "unprognostic (1.87e-1)" 133.1 3.4 3.0 609.4 3.6 0.0 43.6 2.6 8.2 27.7 5.5 34.3 7.9 5.4 3.8 55.6 14.1 69.3 40.8 2.5 2.8 47.7 49.1 48.7 632.5 4.5 3.8 2.4 4.8 0.3 7.9 0.0 4.2 34.3 70.2 0.1 49.5 2.0 0.4 42.8 146.4 32.5 2.9 59.6 68.8 4.0 3.4 526.3 51.6 2.2 603.0 108.4 9.1 2.9 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.6 2.6 8.2 2.5 2.8 4.5 3.8 4.2 2.9 3.4 2.9 3.3 0.0 0.0 0.0 0.8 74.7 0.0 56.9 0.0 0.0 0.4 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 7.3 0.0 0.0 0.0 0.2 0.0 59.6 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 1.3 111.9 0.2 0.0 3.7 92.5 1.0 107.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 150.9 0.7 0.6 0.9 54.0 0.0 6.6 0.0 0.0 0.5 CCL2 "GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF" ENSG00000108691 "C-C motif chemokine ligand 2" P13500 17 34255218-34257203 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 756.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1152.5;Ductal cells: 3382.2;Exocrine glandular cells: 919.2;Prostatic glandular cells: 889.0;Skeletal myocytes: 994.7;Smooth muscle cells: 1507.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 7.5;eosinophil: 3.0" "Group enriched" "Detected in many" 6 "granulocytes: 3.0;monocytes: 7.5" "Group enriched" "Detected in many" 4 "BJ hTERT+: 1902.2;HMC-1: 2427.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 9.9;spinal cord: 39.4" "CAB013676, HPA019163" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 323000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" Vesicles "CAB013676: , HPA019163: AB_1846179" "unprognostic (6.43e-2)" "unprognostic (4.14e-2)" "unprognostic (4.78e-2)" "unprognostic (5.57e-2)" "unprognostic (2.37e-3)" "unprognostic (8.64e-2)" "unprognostic (2.78e-2)" "unprognostic (7.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" "unprognostic (9.33e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (1.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.81e-1)" "unprognostic (4.92e-2)" 390.9 129.8 15.6 167.2 15.1 96.5 76.8 14.7 26.8 20.4 24.4 169.5 41.2 30.2 15.0 47.1 85.6 256.5 305.8 16.0 21.1 229.5 161.1 405.1 78.4 32.7 16.5 19.3 141.6 34.6 70.5 39.1 21.9 153.1 103.5 11.5 47.0 45.4 19.6 40.3 80.3 150.7 21.4 73.2 121.2 12.1 43.3 142.7 84.4 47.0 16.6 756.1 36.3 25.3 0.1 15.3 40.4 0.0 110.7 94.5 0.3 116.6 1902.2 243.3 516.8 7.1 0.2 0.3 90.4 27.6 3.8 64.0 4.3 0.1 122.9 0.6 0.9 0.2 13.5 0.0 3.5 0.4 2427.9 105.9 0.0 50.6 2.9 162.6 112.4 0.0 6.5 20.2 0.0 0.0 0.7 19.6 5.8 0.0 0.4 0.6 3.3 20.9 354.7 0.0 0.1 8.1 0.3 6.0 3.3 108.4 4.6 2.5 6.4 129.0 5.7 3.6 0.7 1.2 0.5 0.1 75.7 37.6 84.3 0.0 7.5 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 1.6 15.6 15.1 14.7 26.8 16.0 21.1 32.7 16.5 21.9 21.4 43.3 25.3 218.3 182.7 126.5 2.0 3.6 568.6 866.2 595.3 1152.5 0.1 23.5 50.9 29.5 92.9 120.7 138.0 0.0 2.7 2.2 0.0 0.0 3382.2 0.0 8.4 37.8 577.2 0.0 0.0 0.7 919.2 3.6 840.5 5.6 11.4 353.0 0.1 50.3 0.4 439.1 0.0 0.1 0.0 6.1 8.9 408.5 0.4 12.2 593.1 213.5 8.4 37.8 13.8 0.0 0.0 0.1 781.2 0.0 1.5 2.9 889.0 0.0 67.7 27.7 0.7 131.5 994.7 1507.0 0.4 0.3 13.0 222.8 4.5 44.3 1.7 0.1 40.6 CCL20 "CKb4, exodus-1, LARC, MIP-3a, SCYA20, ST38" ENSG00000115009 "C-C motif chemokine ligand 20" P78556 2 227805739-227817564 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Antibiotic, Antimicrobial, Cytokine" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 162.6;lymphoid tissue: 165.5;urinary bladder: 192.8" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 25281.7;Club cells: 7424.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.7" "Lineage enriched" "Detected in single" 9 "T-cells: 2.7" "Cell line enhanced" "Detected in many" "GAMG: 63.1;Hep G2: 35.7;NB-4: 25.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 28000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.40e-1)" "unprognostic (1.31e-3)" "unprognostic (1.30e-1)" "unprognostic (2.87e-2)" "unprognostic (7.06e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (9.29e-4)" "unprognostic (1.53e-3)" "unprognostic (1.37e-1)" "unprognostic (5.21e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.19e-8)" "unprognostic (1.39e-1)" "unprognostic (2.75e-1)" "unprognostic (1.63e-1)" "unprognostic (1.82e-1)" 10.1 0.3 1.9 31.8 2.2 7.3 0.7 3.6 2.7 23.9 0.2 19.7 16.4 13.7 0.8 12.2 2.7 162.6 2.0 1.9 1.5 9.1 20.1 35.4 6.2 1.9 1.4 0.9 1.8 0.2 0.2 1.3 2.1 2.8 27.0 1.8 5.0 0.5 0.6 8.2 26.6 4.7 1.5 0.4 11.2 2.1 2.6 2.6 0.6 0.2 165.5 192.8 4.6 3.5 0.5 1.4 0.7 0.9 3.2 6.0 0.9 0.4 2.1 0.2 0.8 3.9 0.6 1.3 4.4 0.0 63.1 0.7 0.2 8.7 1.4 0.9 1.5 0.2 3.3 35.7 2.4 4.7 0.4 10.1 1.8 2.0 2.4 1.0 0.0 1.2 0.3 5.1 0.5 0.4 0.3 25.7 1.8 5.3 0.8 0.7 8.6 1.0 0.3 15.4 0.6 0.5 0.3 1.5 0.9 0.8 1.4 5.7 2.3 3.3 4.1 7.2 0.7 1.0 3.2 2.1 5.0 3.5 6.6 0.0 0.1 0.0 0.0 0.0 2.7 0.1 1.1 0.6 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.2 0.4 0.1 1.9 2.2 3.6 2.7 1.9 1.5 1.9 1.4 2.1 1.5 2.6 3.5 2.8 48.1 108.5 0.0 5.6 118.8 554.4 25281.7 21.6 0.6 1.9 1.9 0.9 65.8 7424.9 18.4 0.0 0.5 2.4 135.0 0.0 310.9 16.0 51.9 44.4 5.1 57.9 0.0 0.0 2.9 0.5 9.2 50.4 517.8 5.7 0.0 0.0 1.7 29.1 1.7 0.0 161.0 2203.3 4.0 149.2 1.2 0.0 333.0 1.8 0.0 9.4 0.0 0.0 0.0 0.0 24.1 459.7 0.0 4.5 259.5 331.0 9.3 1477.8 0.2 0.0 0.7 115.1 1.2 1.2 224.9 64.8 0.8 68.2 0.0 121.9 1062.1 CCL21 "6Ckine, CKb9, ECL, exodus-2, SCYA21, SLC, TCA4" ENSG00000137077 "C-C motif chemokine ligand 21" O00585 9 34709005-34710136 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 2726.3" "Cell type enriched" "Detected in many" 8 "Endothelial cells: 1213.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.1;K-562: 1.2" "Low region specificity" "Detected in some" HPA051210 Enhanced "Secreted to blood" NA NA 198000 920000 "Cluster 16: Immune cells - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051210: AB_2681390" "unprognostic (3.06e-3)" "unprognostic (7.19e-3)" "unprognostic (9.89e-2)" "unprognostic (5.50e-2)" "unprognostic (4.51e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-2)" "unprognostic (8.07e-2)" "unprognostic (4.15e-2)" "unprognostic (2.49e-2)" "unprognostic (3.70e-1)" "unprognostic (8.99e-3)" "unprognostic (3.50e-3)" "unprognostic (1.58e-1)" "unprognostic (2.66e-2)" "unprognostic (8.91e-2)" 173.7 46.9 0.0 269.5 0.1 0.0 180.7 0.1 0.3 154.7 0.6 111.7 46.3 75.6 34.1 128.2 253.3 80.8 41.7 0.1 0.1 75.1 66.0 196.4 2726.3 0.4 0.0 33.9 15.3 0.8 2.5 1.7 0.2 38.2 135.7 0.0 21.5 19.0 6.8 46.4 498.8 69.0 0.0 336.8 60.9 10.3 0.1 28.8 519.4 30.6 998.8 74.1 50.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.7 0.2 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.4 0.0 0.2 0.0 0.1 0.2 58.4 22.4 53.3 0.0 1.9 145.3 2.4 3.8 1.8 0.0 13.5 4.3 10.1 0.0 13.0 1.8 0.0 0.2 1.4 0.2 0.0 10.0 5.7 0.1 0.3 1213.6 0.0 2.7 0.0 3.6 0.2 22.9 0.0 0.2 11.4 0.0 107.1 0.5 0.6 0.0 0.0 2.1 0.0 1.8 148.8 11.0 0.6 6.5 144.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.4 29.6 1.5 0.0 0.0 10.2 0.0 0.0 3.4 120.0 0.2 0.3 11.5 137.7 0.3 9.2 0.0 0.0 0.4 CCL22 "A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, SCYA22, STCP-1" ENSG00000102962 "C-C motif chemokine ligand 22" O00626 16 57358783-57366189 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 5.2;lymphoid tissue: 14.8;skin 1: 6.6;urinary bladder: 4.5" "Cell type enriched" "Detected in some" 27 "monocytes: 5366.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 18 "HDLM-2: 49.6" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 617000 "Cluster 17: Basophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "unprognostic (2.67e-2)" "unprognostic (7.68e-3)" "prognostic favorable (2.98e-4)" "prognostic favorable (2.23e-6)" "unprognostic (8.87e-2)" "prognostic favorable (9.17e-5)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (1.34e-1)" "unprognostic (1.81e-2)" "unprognostic (1.85e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (7.71e-2)" "unprognostic (3.43e-2)" "unprognostic (3.12e-2)" "unprognostic (3.88e-2)" 0.7 0.3 0.3 13.5 0.2 0.6 1.4 0.8 0.3 0.7 0.4 1.6 1.2 0.3 0.1 1.8 0.3 1.8 0.1 0.2 0.1 0.2 0.7 1.8 5.9 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.3 0.4 5.2 0.2 0.7 0.4 0.4 6.6 3.1 0.9 0.1 1.9 1.5 0.4 0.2 14.8 0.3 0.3 14.5 4.5 0.6 0.8 0.5 0.2 0.2 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.7 0.3 0.1 0.1 0.0 1.2 0.1 0.1 0.1 49.6 0.1 0.2 0.3 0.5 0.0 0.2 1.4 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.3 0.3 0.0 0.1 0.2 0.4 0.4 0.2 0.0 0.1 0.2 1.8 0.0 2.7 0.3 0.2 0.2 2.1 0.0 0.2 0.2 2.4 0.4 0.2 0.2 0.1 0.2 0.2 0.1 0.4 0.0 0.2 0.1 1.6 0.2 0.2 0.2 0.1 0.1 1.0 0.1 0.1 0.9 0.4 0.1 0.2 1.2 0.4 0.1 0.3 0.1 0.1 0.3 0.2 0.8 0.3 0.2 0.1 0.3 0.1 0.3 0.1 0.2 0.8 0.1 3.2 1.1 0.0 4.2 6.6 0.3 0.6 0.0 0.0 1.3 0.6 0.4 0.0 1.2 0.0 0.0 0.0 0.1 0.1 1.9 5.9 0.0 0.3 0.1 0.8 0.0 0.0 0.0 21.1 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 194.6 0.0 0.0 10.4 3.6 0.0 5366.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.1 3.9 0.0 0.0 0.0 8.0 0.1 1.2 0.0 0.1 0.4 CCL23 "Ckb-8, CKb8, MIP-3, MPIF-1, SCYA23" ENSG00000274736 "C-C motif chemokine ligand 23" P55773 17 36013056-36017972 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Hepatic stellate cells: 243.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 163 "eosinophil: 183.7" "Lineage enriched" "Detected in many" 163 "granulocytes: 183.7" "Group enriched" "Detected in some" 4 "HEL: 17.6;THP-1: 37.4" HPA042015 Uncertain "Secreted to blood" NA NA 937000 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042015: AB_10794039" "unprognostic (1.65e-3)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (9.50e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-1)" "unprognostic (1.20e-4)" "unprognostic (2.17e-1)" "unprognostic (6.49e-2)" "unprognostic (1.08e-2)" "unprognostic (7.05e-2)" "unprognostic (6.93e-2)" "unprognostic (1.35e-3)" "unprognostic (2.18e-1)" "unprognostic (2.76e-1)" "unprognostic (1.20e-2)" "unprognostic (1.95e-1)" 7.9 6.7 0.0 7.0 0.0 3.7 7.3 0.0 0.2 18.5 0.1 4.3 0.2 14.8 1.6 4.7 11.9 3.3 0.7 0.0 0.0 12.0 7.5 21.4 1.6 0.0 0.0 2.9 1.0 0.0 0.3 0.3 0.0 8.6 8.7 0.0 3.5 0.3 0.5 3.6 9.3 10.8 0.0 14.1 3.3 0.6 0.1 0.8 3.1 0.1 1.3 5.5 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 2.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 1.0 0.7 183.7 0.1 0.7 0.0 1.0 0.0 0.4 0.7 0.0 0.0 0.4 0.7 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.5 3.2 2.3 0.0 0.9 1.7 0.4 0.0 0.0 0.0 0.1 0.3 0.2 1.5 0.6 0.0 0.0 0.0 0.7 1.6 0.0 0.0 1.6 0.0 0.2 44.6 0.0 5.7 0.0 0.0 0.0 0.7 0.0 0.0 10.1 0.0 243.8 2.6 7.0 0.0 0.0 0.5 0.0 14.7 2.7 0.1 0.0 3.7 1.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 21.4 0.0 0.1 0.1 0.5 0.1 1.5 0.0 0.0 0.0 0.5 0.0 0.1 0.1 2.7 0.3 0.6 0.0 4.2 0.2 CCL24 "Ckb-6, eotaxin-2, MPIF-2, MPIF2, SCYA24" ENSG00000106178 "C-C motif chemokine ligand 24" O00175 7 75810825-75823356 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 71.4;lymphoid tissue: 71.8" "Cell type enhanced" "Detected in single" "Macrophages: 1.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 67.6;pancreatic cancer: 17.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.6;OE19: 2.3;U-2 OS: 4.8" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 4 "spinal cord: 9.9" "Secreted to blood" NA NA 276000 "Cluster 11: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (4.55e-2)" "unprognostic (1.13e-1)" "prognostic favorable (5.41e-4)" "unprognostic (1.26e-2)" "unprognostic (1.44e-2)" "unprognostic (5.56e-2)" "unprognostic (1.73e-1)" "unprognostic (1.93e-1)" "unprognostic (4.32e-2)" "unprognostic (1.71e-1)" "unprognostic (2.35e-1)" "unprognostic (3.15e-1)" "unprognostic (2.84e-1)" "unprognostic (2.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.73e-2)" 2.8 0.4 0.4 16.0 0.3 0.8 1.0 1.1 0.6 0.7 0.4 27.4 23.0 0.5 1.2 2.4 0.3 2.0 0.7 0.5 0.2 0.5 5.0 14.2 14.0 0.4 0.3 0.4 0.4 0.5 0.1 0.2 0.4 0.4 71.4 0.5 0.8 0.6 0.5 0.9 63.5 2.3 0.2 71.8 3.5 1.3 0.5 1.6 0.5 0.7 3.2 12.2 0.6 1.2 0.1 0.4 0.3 0.3 0.2 0.6 0.3 0.0 0.1 0.1 0.0 0.1 4.6 0.4 1.4 0.0 0.2 0.3 0.2 0.1 0.2 0.1 0.4 0.1 0.4 0.1 0.0 0.1 1.3 0.9 0.3 0.1 0.1 0.2 0.1 0.2 0.4 0.4 0.0 0.0 0.2 0.6 0.1 2.3 0.2 0.3 1.6 0.2 0.1 0.3 0.3 0.2 0.1 0.2 0.0 0.2 0.4 1.2 0.1 0.4 4.8 0.4 0.4 0.3 0.1 0.1 0.5 0.2 0.1 0.7 0.2 0.1 0.1 0.7 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.5 0.3 0.0 0.2 0.1 0.0 0.4 0.3 1.1 0.6 0.5 0.2 0.4 0.3 0.4 0.2 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 CCL25 "Ckb15, SCYA25, TECK" ENSG00000131142 "C-C motif chemokine ligand 25" O15444 19 8052318-8062660 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 1030 "intestine: 581.5;lymphoid tissue: 771.3" "Cell type enhanced" "Detected in some" "Intestinal goblet cells: 149.1;Proximal enterocytes: 774.7;Undifferentiated cells: 399.3" "Group enriched" "Detected in many" 4 "liver cancer: 25.4;stomach cancer: 33.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "NK-cell: 3.5" "Lineage enriched" "Detected in single" 5 "NK-cells: 3.5" "Cell line enhanced" "Detected in some" "BEWO: 2.0;HEL: 2.1;NB-4: 2.6;REH: 6.1;RPMI-8226: 1.8;SH-SY5Y: 1.9" HPA055883 Approved "Secreted to blood" NA NA 183000000 "Cluster 48: NK-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" "HPA055883: AB_2682955" "unprognostic (9.22e-3)" "unprognostic (3.13e-4)" "unprognostic (1.12e-1)" "unprognostic (1.29e-1)" "unprognostic (2.87e-1)" "unprognostic (9.30e-3)" "unprognostic (2.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (8.85e-3)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (2.27e-4)" "unprognostic (6.43e-2)" "unprognostic (3.86e-1)" "unprognostic (6.57e-2)" "unprognostic (2.17e-1)" 0.0 0.0 0.2 0.6 0.2 0.0 0.0 0.2 0.5 0.0 0.1 1.3 512.4 0.3 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.2 0.0 1.4 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 581.5 0.0 0.1 0.5 0.5 0.6 0.3 771.3 0.2 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.6 0.1 0.0 0.3 6.1 0.0 1.8 0.0 0.0 0.4 1.9 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 0.1 0.2 0.2 0.2 0.5 0.2 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.2 0.2 1.6 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 149.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 57.6 0.0 1.5 0.0 774.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 399.3 0.0 CCL26 "eotaxin-3, IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1" ENSG00000006606 "C-C motif chemokine ligand 26" Q9Y258 7 75769533-75789896 "Human disease related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 20.4;pituitary gland: 16.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 7.1;Intestinal goblet cells: 7.7;Leydig cells: 16.8;Sertoli cells: 13.1;Smooth muscle cells: 20.2" "Cancer enhanced" "Detected in many" "testis cancer: 14.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 11.2;hTEC/SVTERT24-B: 14.8;PC-3: 51.1;U-2 OS: 13.7" "Region enriched" "Detected in single" 16 "spinal cord: 1.7" "Secreted to blood" NA NA 117000 "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (1.14e-1)" "unprognostic (4.17e-1)" "unprognostic (2.22e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (3.52e-2)" "unprognostic (2.18e-2)" "unprognostic (6.17e-2)" "unprognostic (3.02e-1)" "unprognostic (8.71e-2)" "unprognostic (7.93e-2)" "unprognostic (2.47e-1)" "unprognostic (1.05e-11)" "unprognostic (2.46e-2)" "unprognostic (1.10e-1)" "unprognostic (3.73e-1)" "unprognostic (6.29e-3)" 2.7 3.1 1.5 0.6 1.7 0.0 1.9 1.6 3.7 3.1 10.1 0.8 0.3 1.2 1.9 1.8 2.7 1.4 3.9 1.5 1.5 1.7 0.4 1.9 3.4 1.7 1.5 20.4 0.4 3.2 16.4 0.4 1.6 1.0 7.2 2.5 0.7 0.3 0.4 1.9 1.0 1.4 1.7 0.4 0.9 1.2 1.9 0.3 0.6 0.1 0.2 3.6 4.3 1.5 0.2 11.2 0.0 0.0 1.3 1.7 0.0 0.6 5.2 4.3 7.3 0.3 3.2 0.0 7.2 3.5 0.3 2.1 0.0 0.0 5.8 0.0 0.5 0.0 0.0 1.1 0.5 0.0 0.0 0.0 0.6 14.8 0.1 2.3 0.0 0.0 5.2 0.0 2.2 0.7 0.0 0.0 8.4 0.5 51.1 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.6 0.1 0.0 2.2 0.0 0.0 0.3 8.2 13.7 4.2 2.7 0.0 0.0 0.0 2.5 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 1.6 3.7 1.5 1.5 1.7 1.5 1.6 1.7 1.9 1.5 0.5 0.0 0.0 0.0 0.0 1.1 3.5 1.8 0.0 0.5 0.1 0.1 0.4 0.0 0.7 0.0 4.2 0.0 0.0 2.3 0.0 0.0 0.5 0.1 1.1 0.6 0.0 0.0 0.1 0.0 0.0 7.1 0.5 0.1 0.0 0.1 1.1 0.0 0.0 0.0 0.1 7.7 0.0 3.2 1.4 0.9 16.8 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.1 4.9 0.0 0.6 0.1 0.0 0.2 2.2 13.1 0.9 20.2 0.1 0.4 0.6 1.8 0.0 0.2 2.5 1.6 2.6 CCL27 "ALP, CTACK, CTAK, ESkine, ILC, PESKY, SCYA27, skinkine" ENSG00000213927 "C-C motif chemokine ligand 27" Q9Y4X3 9 34661880-34664048 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 485.0" "Group enriched" "Detected in some" 26 "Basal keratinocytes: 704.5;Suprabasal keratinocytes: 1004.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.9" "Not detected" "Not detected" HPA073848 Enhanced "Secreted to blood" NA NA 436000 1800000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 61: Skin - Cornification" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" "HPA073848: AB_2732243" 0.3 0.0 1.8 0.1 1.8 1.6 27.6 3.5 4.8 0.6 1.5 0.1 0.3 0.7 3.1 0.7 0.2 0.7 0.6 1.8 1.8 0.0 0.3 0.1 0.3 2.0 1.8 0.9 0.1 0.1 0.1 0.3 1.9 0.2 0.2 0.9 0.3 0.1 1.4 485.0 0.1 0.2 1.9 0.1 0.1 1.3 1.8 4.6 1.2 0.3 0.2 0.1 0.6 2.2 0.0 0.0 0.3 1.9 0.8 0.3 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 1.1 0.7 0.0 0.0 1.1 0.4 0.3 0.0 0.0 1.4 0.8 0.2 0.0 0.3 0.0 0.5 0.2 1.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 1.2 0.0 0.1 0.5 0.0 0.0 0.1 1.3 0.7 0.0 0.0 0.9 0.8 0.7 0.0 0.1 0.1 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 1.8 3.5 4.8 1.8 1.8 2.0 1.8 1.9 1.9 1.8 2.2 0.1 0.0 0.0 0.3 0.0 704.5 0.3 0.3 0.0 0.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 7.8 0.0 0.3 1.7 0.0 0.0 0.2 0.2 0.8 2.3 0.0 0.1 0.0 0.1 0.4 0.1 0.2 0.0 0.1 0.2 0.0 0.0 28.4 9.6 0.3 0.0 32.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.6 0.5 0.0 0.2 0.0 0.2 1.6 4.5 1.5 0.0 1004.0 1.9 0.8 0.0 0.2 0.1 CCL28 "CCK1, MEC, SCYA28" ENSG00000151882 "C-C motif chemokine ligand 28" Q9NRJ3 5 43376645-43412391 "Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 302.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 192.4;Breast myoepithelial cells: 147.4;Distal enterocytes: 172.9;Ductal cells: 110.1;Paneth cells: 117.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 10.7;EFO-21: 12.8;SiHa: 29.9;SK-MEL-30: 16.7;T-47d: 40.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA077434 Supported "Secreted to blood" NA NA 700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 30: Mammary glandular cells - Lactation" "HPA077434: AB_2732346" "unprognostic (1.04e-2)" "unprognostic (2.66e-1)" "unprognostic (8.14e-3)" "unprognostic (1.94e-2)" "unprognostic (8.85e-4)" "unprognostic (4.93e-3)" "unprognostic (1.20e-3)" "unprognostic (3.56e-2)" "unprognostic (4.91e-3)" "unprognostic (4.14e-2)" "prognostic unfavorable (1.43e-4)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (2.52e-1)" "unprognostic (1.78e-1)" "unprognostic (6.53e-2)" 1.7 1.2 0.7 4.6 0.9 3.3 60.9 0.8 0.9 14.3 0.9 30.7 24.1 2.3 1.4 4.0 4.3 19.7 1.0 0.7 0.5 2.8 1.8 2.9 4.6 0.8 1.5 1.5 7.9 2.2 1.1 3.1 0.9 3.1 28.3 2.1 302.4 2.3 0.3 5.4 12.6 1.9 0.4 4.3 15.0 1.6 0.5 2.4 22.6 0.5 3.9 1.4 2.1 1.5 0.8 0.0 0.1 0.2 0.9 0.1 4.7 0.7 0.4 0.0 0.0 2.1 10.7 0.1 12.8 0.3 0.0 1.6 0.0 0.2 0.0 0.1 0.2 0.8 1.2 0.0 0.7 0.1 0.2 1.0 2.7 0.2 0.5 0.4 0.1 0.1 0.1 0.1 1.2 0.2 1.9 0.1 0.1 0.0 1.6 0.1 0.0 0.5 0.1 1.3 0.2 0.1 29.9 1.1 16.7 0.3 40.1 8.0 0.2 0.1 1.2 0.2 0.1 0.7 0.1 0.1 0.0 0.1 8.9 4.0 0.2 0.3 3.2 0.2 2.5 4.0 3.7 2.7 0.6 4.3 4.3 3.1 0.7 3.5 0.1 0.9 6.0 1.4 0.7 0.9 0.8 0.9 0.7 0.5 0.8 1.5 0.9 0.4 0.5 1.5 4.0 0.0 7.7 1.6 10.9 2.7 4.9 15.6 5.7 0.1 192.4 147.4 0.4 62.9 17.9 5.5 0.0 6.2 10.1 172.9 5.9 110.1 3.7 12.9 1.9 6.4 3.6 2.5 1.7 66.4 3.2 2.9 36.2 13.0 11.4 0.0 7.5 1.9 2.6 0.0 0.7 48.5 20.3 1.2 1.2 1.2 12.5 1.5 17.8 2.8 1.3 9.6 17.5 0.5 0.9 21.7 117.0 4.9 1.2 13.7 38.7 0.2 46.2 0.9 0.0 0.4 2.6 5.3 3.1 6.1 1.3 2.7 9.5 0.5 58.5 24.4 CCL3 "G0S19-1, LD78ALPHA, MIP-1-alpha, SCYA3" ENSG00000277632 "C-C motif chemokine ligand 3" P10147 17 36088256-36090169 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.7;lung: 35.8;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in many" "dendritic cells: 441.4;Hofbauer cells: 2084.4;Kupffer cells: 723.2;Langerhans cells: 710.0;Macrophages: 1534.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "gdT-cell: 23.6" "Group enriched" "Detected in many" 4 "B-cells: 10.4;granulocytes: 10.8;T-cells: 23.6" "Cell line enhanced" "Detected in some" "Karpas-707: 443.8;U-266/70: 602.5;U-266/84: 2043.3" "Secreted to blood" NA NA 138000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.45e-1)" "unprognostic (7.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.66e-1)" "unprognostic (3.54e-1)" "unprognostic (8.90e-2)" "unprognostic (7.92e-3)" "unprognostic (2.00e-1)" "unprognostic (7.20e-2)" "unprognostic (2.05e-1)" "unprognostic (8.92e-3)" "unprognostic (1.08e-1)" "unprognostic (9.29e-2)" "unprognostic (1.55e-2)" "unprognostic (1.23e-2)" 17.6 16.0 0.0 8.1 0.7 76.7 5.6 0.0 1.4 1.5 0.0 2.5 0.0 1.1 0.0 0.5 2.9 10.3 3.7 0.0 0.0 4.6 12.9 35.8 1.8 0.7 0.0 1.2 1.3 0.0 1.7 2.4 0.0 2.2 0.0 0.0 5.6 0.0 0.8 0.8 3.1 0.0 0.0 49.4 3.0 0.7 0.5 0.0 2.0 0.0 0.0 3.0 1.4 1.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 443.8 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 55.6 0.0 0.0 1.3 602.5 2043.3 0.0 0.0 0.0 0.0 0.0 2.1 10.8 23.6 1.3 0.0 5.1 0.0 6.1 0.4 10.4 0.1 6.8 10.5 3.5 1.3 0.0 0.0 11.6 0.0 0.7 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.5 1.4 33.0 0.0 28.6 0.0 45.3 27.9 2.0 0.2 1.2 1.8 23.1 50.0 2.2 4.3 4.4 0.0 0.0 19.0 441.4 0.7 0.0 0.6 1.5 1.6 2.5 115.9 0.0 61.9 0.0 0.2 22.6 14.5 2.0 2.8 23.5 0.1 27.1 9.1 2084.4 0.0 0.0 0.5 0.0 723.2 710.0 1.9 1.8 1534.2 94.3 2.8 23.5 2.1 106.1 0.0 0.0 0.4 0.0 0.0 344.8 1.2 0.0 0.9 2.2 3.7 6.6 2.3 9.2 0.5 0.6 0.6 28.8 54.3 248.0 0.1 0.2 1.3 CCL3L3 "CCL3L1, D17S1718, G0S19-2, LD78BETA, MGC12815, SCYA3L, SCYA3L1" ENSG00000276085 "C-C motif chemokine ligand 3 like 3" P16619 17 36194869-36196758 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.0;lung: 5.0;lymphoid tissue: 4.0" "Group enriched" "Detected in some" 6 "Hofbauer cells: 335.4;Kupffer cells: 227.5;Macrophages: 321.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "eosinophil: 4.2;neutrophil: 1.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Group enriched" "Detected in some" 41 "U-266/70: 49.4;U-266/84: 107.3" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 4: Macrophages - Innate immune response" "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "unprognostic (5.37e-2)" "unprognostic (1.46e-1)" "unprognostic (9.50e-2)" "unprognostic (2.18e-1)" "unprognostic (4.36e-2)" "unprognostic (3.69e-1)" "unprognostic (5.75e-2)" "unprognostic (5.55e-2)" "unprognostic (2.40e-2)" "unprognostic (3.66e-1)" "unprognostic (9.08e-2)" "unprognostic (2.09e-1)" "unprognostic (3.21e-1)" "unprognostic (1.90e-2)" "unprognostic (8.58e-2)" 1.6 0.9 0.0 0.3 0.0 11.0 0.7 0.0 0.3 0.1 0.0 0.5 0.1 0.2 0.2 0.1 0.7 0.9 0.4 0.0 0.0 1.1 1.2 5.0 0.5 0.0 0.0 0.2 0.2 0.0 0.3 0.3 0.0 0.5 0.0 0.0 1.3 0.1 0.1 0.1 0.8 0.1 0.0 4.0 0.5 0.5 0.0 0.1 0.3 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.1 49.4 107.3 1.2 0.0 0.0 0.0 0.1 0.0 4.2 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.3 0.5 0.0 2.2 0.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 3.9 0.0 0.7 0.0 0.0 0.1 0.0 0.0 48.8 0.0 16.0 0.0 0.0 4.4 1.3 0.5 0.0 0.0 0.0 8.6 1.0 335.4 0.0 0.0 0.5 0.0 227.5 2.9 0.9 0.6 321.7 1.8 1.9 1.6 0.7 10.3 0.0 0.0 0.0 1.2 0.0 0.8 0.7 0.0 0.0 0.0 2.3 0.0 0.4 0.3 0.4 3.8 0.7 0.1 13.1 31.4 0.0 0.0 0.4 CCL4 "Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4" ENSG00000275302 "C-C motif chemokine ligand 4" P13236 17 36103827-36105621 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.9" "Cell type enhanced" "Detected in many" "dendritic cells: 3753.7;Hofbauer cells: 849.7;Macrophages: 1168.2;NK-cells: 1232.8;Plasma cells: 974.5;T-cells: 1948.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 414.7" "Group enriched" "Detected in all" 6 "granulocytes: 135.0;T-cells: 414.7" "Group enriched" "Detected in some" 6 "U-266/70: 51.6;U-266/84: 13.3" CAB007805 Approved "Secreted to blood" NA NA 144000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB007805: AB_598177" "unprognostic (6.03e-2)" "unprognostic (2.48e-2)" "prognostic favorable (3.54e-4)" "prognostic favorable (1.97e-5)" "unprognostic (2.06e-1)" "unprognostic (7.02e-2)" "unprognostic (9.08e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.97e-4)" "unprognostic (3.45e-1)" "unprognostic (8.57e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (3.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-2)" 38.9 28.0 2.0 32.0 2.0 192.9 10.5 3.4 5.5 16.0 4.1 9.9 7.6 10.3 6.4 15.0 8.2 45.1 4.4 2.0 1.9 6.8 84.2 33.9 34.3 3.2 2.9 5.0 15.6 12.0 2.5 17.8 2.8 7.6 11.1 0.1 5.1 3.4 1.0 0.9 11.4 18.0 2.5 65.3 10.3 2.7 2.1 24.1 5.9 4.5 15.4 56.4 4.4 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.0 0.0 51.6 13.3 0.2 0.2 0.1 0.0 14.4 3.4 135.0 414.7 4.8 101.6 8.4 46.0 240.6 2.3 17.7 13.8 181.7 55.8 42.8 11.1 2.6 0.5 138.9 2.0 2.0 3.4 5.5 2.0 1.9 3.2 2.9 2.8 2.5 2.1 3.3 52.3 0.0 54.5 0.0 135.9 15.6 1.9 0.3 24.5 1.5 26.3 49.3 11.2 14.3 7.2 0.0 0.0 9.7 3753.7 1.2 0.0 0.4 20.8 3.7 4.7 77.6 1.2 60.9 0.0 0.4 11.3 18.9 118.3 5.5 60.8 0.2 21.4 10.5 849.7 1.7 0.0 1.5 0.0 429.4 428.0 32.6 0.9 1168.2 51.6 3.7 10.5 1.1 1232.8 0.0 0.0 0.2 0.1 0.4 974.5 0.8 0.4 2.8 5.8 5.2 0.0 3.9 20.9 0.4 0.4 11.0 14.5 25.9 1948.3 0.0 0.9 1.6 CCL4L2 ENSG00000276070 "C-C motif chemokine ligand 4 like 2" Q8NHW4 17 36210924-36212878 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.2;lymphoid tissue: 20.5" "Group enriched" "Detected in many" 6 "dendritic cells: 488.0;Hofbauer cells: 358.5;Kupffer cells: 163.4;Macrophages: 585.2;NK-cells: 249.3;T-cells: 303.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 7 "eosinophil: 122.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 122.0" "Group enriched" "Detected in some" 4 "Daudi: 4.1;HMC-1: 5.6;U-266/70: 8.8" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.79e-1)" "unprognostic (1.17e-1)" "unprognostic (2.46e-2)" "unprognostic (1.44e-2)" "unprognostic (1.16e-1)" "unprognostic (6.07e-2)" "unprognostic (3.82e-1)" "unprognostic (3.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.14e-1)" "unprognostic (3.62e-2)" "unprognostic (1.93e-1)" "unprognostic (1.27e-2)" "unprognostic (2.27e-1)" "unprognostic (2.08e-1)" "unprognostic (8.51e-2)" "unprognostic (1.99e-3)" 5.5 3.8 0.3 4.4 0.3 32.2 1.5 0.5 1.1 0.9 0.4 1.7 1.5 1.1 0.5 0.7 2.6 6.8 1.3 0.4 0.3 3.1 7.6 12.6 3.2 0.3 0.3 1.9 0.9 2.0 1.1 2.2 0.3 1.9 1.8 0.0 2.0 0.7 0.2 0.4 3.8 1.5 0.3 20.5 1.8 0.2 0.3 1.6 1.4 1.7 0.8 4.8 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.8 1.5 0.7 0.0 0.0 0.0 0.6 0.3 122.0 15.2 0.3 3.6 0.0 0.6 8.9 0.1 0.1 0.1 8.4 18.2 1.2 0.2 0.0 0.0 5.5 0.3 0.3 0.5 1.1 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.4 18.1 0.0 7.7 0.7 13.9 0.4 0.4 0.0 5.7 0.4 13.8 22.9 8.6 4.3 0.0 0.0 0.0 4.2 488.0 0.2 0.0 0.1 0.2 0.4 1.0 38.1 0.0 14.3 1.1 0.0 6.1 3.9 3.1 0.8 5.1 8.2 7.1 1.3 358.5 1.7 0.4 0.1 0.0 163.4 59.1 1.2 0.0 585.2 1.8 6.5 3.3 1.3 249.3 0.0 0.1 0.1 0.1 0.0 50.6 0.4 0.0 0.2 0.0 2.3 13.1 1.1 6.6 0.1 0.1 1.4 0.4 9.6 303.6 0.1 0.0 1.8 CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.1;lymphoid tissue: 135.2" "Group enriched" "Detected in many" 8 "dendritic cells: 2049.9;NK-cells: 2344.0;T-cells: 1947.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6788.6;memory CD8 T-cell: 7164.3" "Group enriched" "Detected in all" 7 "NK-cells: 2041.1;T-cells: 7164.3" "Cell line enhanced" "Detected in some" "HL-60: 94.1;NB-4: 539.9;THP-1: 139.9;U-937: 120.1" CAB078447 Enhanced "Secreted to blood" NA NA 20100000 2900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" 17.2 17.1 3.9 36.3 4.0 122.1 19.5 3.8 6.5 15.5 5.4 27.7 48.7 15.7 14.4 15.8 14.0 42.9 8.9 3.9 3.7 7.5 28.4 57.4 135.2 7.3 4.3 16.9 7.0 3.0 3.8 6.3 6.4 10.4 25.6 0.3 33.5 7.9 4.8 4.0 84.5 10.5 5.8 123.9 47.9 4.6 4.7 29.5 11.5 2.7 33.4 31.4 9.5 6.1 0.7 0.5 0.2 0.0 0.5 0.4 0.8 0.3 4.0 17.8 20.8 0.4 1.7 0.3 1.6 0.9 1.3 0.9 0.0 0.0 2.3 6.5 0.3 0.0 1.5 0.6 0.5 94.1 0.8 0.1 0.2 5.5 0.3 0.0 0.2 0.1 0.1 12.5 0.2 0.6 0.1 539.9 0.5 0.0 0.0 0.6 0.2 14.0 0.2 0.5 0.1 0.5 0.2 1.2 13.4 0.5 0.2 139.9 0.3 0.6 0.3 0.6 0.4 14.2 6.6 0.8 0.4 120.1 1.3 657.8 30.0 35.8 6788.6 21.3 4221.0 61.3 1394.5 7164.3 49.8 41.6 332.4 4032.4 189.9 2041.1 26.1 46.5 25.9 6664.4 3.9 4.0 3.8 6.5 3.9 3.7 7.3 4.3 6.4 5.8 4.7 6.1 22.4 99.3 244.4 0.3 55.2 7.4 1.3 6.0 4.6 1.3 19.9 18.2 5.4 21.5 41.7 1.8 0.0 1.8 2049.9 3.1 1.9 6.3 1.2 5.5 5.4 24.2 1.8 106.3 0.5 0.2 7.1 26.0 46.9 6.7 80.8 0.2 45.0 7.0 33.8 0.0 0.3 3.5 0.0 48.0 25.0 0.1 0.3 256.3 12.4 2.8 38.5 0.4 2344.0 0.0 0.4 1.6 6.9 0.4 179.5 1.7 2.4 6.7 29.2 1.1 0.0 6.5 28.2 1.1 1.2 5.5 6.3 16.0 1947.0 0.1 3.5 1.9 CCL7 "FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7" ENSG00000108688 "C-C motif chemokine ligand 7" P80098 17 34270221-34272242 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "bone marrow: 25.9" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 56.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 6 "thalamus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.5;BJ hTERT+ SV40 Large T+: 2.3;BJ hTERT+ SV40 Large T+ RasG12V: 2.8;HSkMC: 3.3" "Not detected" "Not detected" "Secreted to blood" NA NA 29700 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (7.66e-2)" "unprognostic (1.05e-2)" "unprognostic (8.53e-2)" "unprognostic (4.65e-2)" "unprognostic (2.54e-2)" "unprognostic (9.54e-2)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (2.63e-2)" "unprognostic (2.27e-3)" "unprognostic (7.04e-2)" "unprognostic (1.99e-8)" "unprognostic (2.83e-1)" "unprognostic (8.74e-2)" "unprognostic (3.74e-1)" "unprognostic (1.79e-2)" 0.8 0.2 0.0 2.5 0.0 25.9 0.1 0.0 0.3 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.7 0.3 0.0 0.0 0.5 0.2 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.0 2.3 0.3 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 11.5 2.3 2.8 0.0 0.0 0.0 0.4 0.8 0.0 1.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 3.3 0.0 0.9 0.0 0.0 1.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 CCL8 "HC14, MCP-2, SCYA8" ENSG00000108700 "C-C motif chemokine ligand 8" P80075 17 34319435-34321402 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Smooth muscle cells: 104.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 6 "monocytes: 3.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.1;BJ hTERT+ SV40 Large T+ RasG12V: 1.0;EFO-21: 2.1;HSkMC: 3.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 32000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (7.51e-2)" "unprognostic (3.20e-1)" "unprognostic (1.90e-2)" "unprognostic (4.03e-2)" "unprognostic (8.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (9.97e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.05e-7)" "unprognostic (1.39e-1)" "unprognostic (1.88e-2)" "unprognostic (5.65e-2)" "unprognostic (3.41e-2)" 17.5 4.7 0.4 5.1 0.4 1.8 6.2 0.4 0.9 1.5 0.5 18.1 14.1 7.3 1.9 3.5 1.3 8.8 2.7 0.4 0.4 7.7 3.2 7.1 3.9 0.6 0.4 1.4 1.1 4.8 0.5 7.1 0.6 2.2 16.4 0.0 1.9 1.3 0.4 0.5 17.0 9.3 1.8 2.9 2.9 3.1 1.1 12.5 2.3 7.0 0.5 13.7 0.3 0.6 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.1 0.0 1.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.4 0.9 0.4 0.4 0.6 0.4 0.6 1.8 1.1 0.6 21.5 0.0 0.0 0.0 0.1 4.2 0.3 0.5 0.0 0.0 0.9 1.1 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 10.5 0.9 7.5 9.6 0.0 0.0 0.0 2.0 0.0 16.4 0.0 1.6 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 3.5 18.6 2.2 0.0 12.7 5.4 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.3 104.3 0.0 0.0 0.0 5.4 0.1 0.8 0.7 0.0 0.1 CCN1 "CYR61, GIG1, IGFBP10" ENSG00000142871 "Cellular communication network factor 1" O00622 1 85580761-85584589 "Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Growth factor binding, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 256.5;Cardiomyocytes: 107.6;Cytotrophoblasts: 258.1;Extravillous trophoblasts: 529.9;Fibroblasts: 296.2;Syncytiotrophoblasts: 131.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebral cortex: 25.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 431.8;BJ hTERT+ SV40 Large T+: 422.0;EFO-21: 410.9;SiHa: 551.2;TIME: 541.3;U-251 MG: 642.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029853 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA029853: AB_10611822" "unprognostic (6.09e-2)" "unprognostic (3.25e-2)" "unprognostic (9.97e-2)" "unprognostic (8.90e-2)" "unprognostic (1.80e-2)" "unprognostic (3.91e-2)" "unprognostic (3.47e-2)" "unprognostic (1.56e-2)" "unprognostic (2.59e-1)" "unprognostic (9.95e-2)" "unprognostic (1.35e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.04e-3)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (3.74e-3)" 571.1 99.7 1.0 28.2 3.9 0.2 313.4 1.0 25.0 255.7 9.6 197.1 5.1 273.6 0.1 48.7 472.4 64.8 400.6 3.7 0.0 212.8 200.5 407.8 3.8 4.9 3.8 123.1 70.7 14.8 56.0 29.8 3.1 157.3 1.7 1.1 94.2 2.9 97.8 197.1 102.0 141.7 0.0 131.2 201.7 20.1 5.1 11.1 268.1 17.3 0.0 264.4 150.8 3.6 159.3 5.2 0.7 1.0 47.4 90.6 77.4 431.8 216.6 422.0 264.6 24.1 4.3 0.0 410.9 185.5 82.8 36.3 15.9 33.4 164.4 0.7 6.9 0.3 6.8 0.7 245.2 3.7 0.2 39.9 6.9 121.2 50.1 13.4 366.0 0.1 1.6 0.0 150.3 0.8 0.3 0.7 24.9 1.8 42.2 0.4 94.9 0.7 166.0 2.5 0.4 4.0 551.2 17.7 62.1 4.9 16.5 0.8 541.3 272.3 213.3 82.2 642.6 0.3 0.7 1.8 1.9 0.2 73.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.9 1.0 25.0 3.7 0.0 4.9 3.8 3.1 0.0 5.1 3.6 256.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.6 0.0 0.0 0.0 0.0 258.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 529.9 296.2 0.0 0.0 0.0 0.0 0.0 0.0 40.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 89.1 0.0 0.0 0.0 0.0 131.3 0.0 0.0 0.0 0.0 CCN2 "CTGF, IGFBP8" ENSG00000118523 "Cellular communication network factor 2" P29279 6 131948176-131951372 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cell adhesion, DNA synthesis" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 101.2;Cardiomyocytes: 38.7;Extravillous trophoblasts: 47.1;Fibroblasts: 261.8;Smooth muscle cells: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 8.1" "Lineage enriched" "Detected in single" 81 "B-cells: 8.1" "Cell line enhanced" "Detected in many" "EFO-21: 1605.0;HUVEC TERT2: 1377.0;TIME: 2874.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005123, HPA031074, HPA031075" Approved Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" No No 1010000 5900000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "CAB005123: AB_638805, HPA031074: AB_10599618, HPA031075: AB_10611248" "unprognostic (2.87e-1)" "unprognostic (1.43e-1)" "unprognostic (4.41e-2)" "unprognostic (5.68e-2)" "unprognostic (9.79e-2)" "unprognostic (1.82e-2)" "unprognostic (3.38e-1)" "unprognostic (4.96e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.27e-3)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.62e-1)" "unprognostic (1.77e-2)" "unprognostic (3.84e-3)" 265.9 107.5 18.9 168.0 18.8 2.0 206.4 16.3 34.0 531.0 31.5 148.8 43.7 418.5 34.4 271.9 243.8 441.4 371.8 25.8 14.2 235.7 82.9 226.3 73.6 18.8 32.1 77.0 194.0 43.0 44.8 198.2 20.2 364.6 136.1 2.4 138.2 154.3 51.8 155.1 151.2 576.3 14.2 569.1 182.6 24.7 20.8 49.5 464.7 61.9 14.9 324.0 102.5 18.2 4.6 7.5 126.8 3.7 279.9 158.5 1.8 373.1 178.2 226.8 119.4 0.2 12.2 0.6 1605.0 482.7 185.0 6.2 4.2 26.4 211.3 2.5 3.5 0.2 55.7 137.3 109.6 0.3 0.5 232.2 5.9 163.9 40.2 340.7 1377.0 0.0 0.4 0.3 650.8 2.5 0.5 1.2 61.8 41.3 21.7 32.6 6.0 0.7 81.9 0.4 0.5 0.8 38.3 62.2 18.3 308.5 6.1 3.1 2874.4 311.6 242.4 397.8 694.0 11.5 1.7 4.1 42.5 0.7 399.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.9 18.8 16.3 34.0 25.8 14.2 18.8 32.1 20.2 14.2 20.8 18.2 101.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 0.0 0.0 0.0 17.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 47.1 261.8 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.4 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 CCN3 "IGFBP9, NOV" ENSG00000136999 "Cellular communication network factor 3" P48745 8 119416446-119424434 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "adrenal gland: 1105.4" "Cell type enhanced" "Detected in some" "Adipocytes: 25.2;Endothelial cells: 2.7;Fibroblasts: 9.8;Smooth muscle cells: 4.6" "Cancer enriched" "Detected in all" 4 "melanoma: 62.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 116 "eosinophil: 64.8;neutrophil: 30.8" "Lineage enriched" "Detected in single" 157 "granulocytes: 64.8" "Cell line enhanced" "Detected in many" "BJ hTERT+: 125.0;hTERT-RPE1: 38.1;U-2197: 128.2" "Group enriched" "Detected in all" 6 "amygdala: 129.2;basal ganglia: 51.5;cerebral cortex: 99.5;hippocampal formation: 152.5;white matter: 85.0" "Region enriched" "Detected in all" 6 "spinal cord: 114.6" "HPA018449, HPA019684, CAB034423" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 269000000 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB034423: AB_2151387, HPA018449: AB_1846189, HPA019684: AB_1846190" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.36e-3)" "unprognostic (1.30e-3)" "unprognostic (9.35e-3)" "unprognostic (4.92e-1)" "unprognostic (8.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.74e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (2.72e-2)" 23.7 1105.4 7.6 3.6 11.5 1.7 8.1 6.7 12.2 11.2 5.9 6.9 3.9 8.6 6.3 5.5 9.0 6.3 18.1 16.2 9.7 6.9 1.1 6.8 2.2 5.6 6.5 3.1 6.8 9.4 21.8 0.6 4.9 22.8 7.0 1.2 2.7 20.0 4.7 13.8 4.4 8.4 8.7 1.5 4.9 3.6 6.3 1.0 25.3 7.2 1.9 4.4 8.0 6.2 0.1 3.1 1.7 0.0 11.1 2.9 0.1 16.9 125.0 14.9 8.6 0.0 0.3 0.0 12.9 21.2 11.6 10.5 0.6 0.0 5.1 0.0 0.3 0.0 9.1 0.0 0.4 0.0 0.0 0.6 0.1 5.7 0.6 38.1 0.4 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.2 1.2 24.9 0.1 0.0 0.0 15.8 0.1 3.9 0.1 6.3 0.1 24.2 0.0 0.0 0.0 0.0 10.6 15.8 128.2 3.5 0.0 0.0 0.0 16.7 5.4 12.5 0.0 0.3 64.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 30.8 0.0 0.0 0.0 0.0 0.1 7.6 11.5 6.7 12.2 16.2 9.7 5.6 6.5 4.9 8.7 6.3 6.2 25.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CCN4 "WISP-1, WISP1, WISP1-OT1, WISP1-UT1" ENSG00000104415 "Cellular communication network factor 4" O95388 8 133191039-133231690 "Cancer-related genes, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HSkMC: 110.5;hTEC/SVTERT24-B: 64.5;U-2197: 61.9" "Region enriched" "Detected in some" 6 "olfactory bulb: 9.8" "Low region specificity" "Detected in many" "HPA007121, CAB012205" Uncertain Approved Cytosol "Secreted to extracellular matrix" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB012205: , HPA007121: AB_1858844" "unprognostic (7.77e-2)" "unprognostic (2.05e-1)" "unprognostic (3.30e-2)" "unprognostic (3.20e-1)" "unprognostic (7.72e-2)" "unprognostic (6.63e-2)" "unprognostic (8.61e-3)" "unprognostic (3.26e-2)" "unprognostic (2.07e-3)" "unprognostic (1.41e-3)" "unprognostic (3.01e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (7.52e-3)" "unprognostic (2.55e-3)" "unprognostic (6.03e-2)" "unprognostic (5.67e-3)" 4.4 10.3 1.3 7.6 2.6 0.0 0.9 0.5 1.4 10.9 0.9 3.9 1.2 14.0 0.9 0.9 5.9 7.8 3.7 1.3 0.4 15.8 2.0 8.3 3.0 0.7 0.6 6.0 0.8 9.2 2.3 2.8 0.7 3.3 0.8 0.0 1.1 1.4 0.4 1.4 2.3 13.6 0.6 2.2 2.8 1.2 0.9 0.2 1.1 0.2 3.9 6.0 3.6 0.8 0.0 0.5 0.0 0.0 7.6 4.2 0.1 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 110.5 0.0 64.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.6 0.0 0.0 0.0 14.8 0.8 61.9 0.0 0.0 0.0 0.0 12.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.6 0.5 1.4 1.3 0.4 0.7 0.6 0.7 0.6 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CCN5 "CT58, CTGF-L, WISP-2, WISP2" ENSG00000064205 "Cellular communication network factor 5" O76076 20 44714844-44728509 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 394.6;cervix: 355.7" "Cell type enriched" "Detected in some" 6 "Fibroblasts: 165.2" "Cancer enhanced" "Detected in many" "melanoma: 8.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 42.6;ASC TERT1: 113.8;HeLa: 62.7;HSkMC: 46.5;U-2197: 375.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB019273 Approved "Secreted to extracellular matrix" NA NA 1200000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB019273: " "unprognostic (1.87e-1)" "unprognostic (2.64e-1)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.70e-1)" "unprognostic (2.83e-1)" "unprognostic (1.83e-1)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (9.42e-2)" "unprognostic (2.81e-1)" "unprognostic (7.95e-3)" "unprognostic (1.76e-10)" "unprognostic (1.55e-3)" "unprognostic (7.21e-2)" "unprognostic (4.84e-2)" "unprognostic (1.28e-1)" 394.6 41.5 1.8 0.7 2.0 0.2 116.5 0.9 2.9 355.7 0.7 23.6 0.7 35.3 0.7 25.4 39.0 7.7 161.1 1.6 1.3 0.7 5.6 136.4 1.9 1.4 1.4 147.1 4.4 0.6 0.8 1.4 1.4 37.0 1.6 0.1 30.7 25.5 39.2 197.1 11.5 6.5 1.0 4.0 11.4 33.1 1.4 1.3 14.2 5.1 0.4 36.7 111.6 1.5 0.0 3.7 0.1 0.0 42.6 113.8 0.0 0.2 1.2 0.1 0.2 0.0 0.0 0.1 0.5 0.7 3.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 62.7 0.0 0.1 0.1 0.1 46.5 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.7 1.1 0.3 0.0 1.9 0.2 0.0 0.1 0.2 375.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.0 0.9 2.9 1.6 1.3 1.4 1.4 1.4 1.0 1.4 1.5 25.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 165.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCN6 "WISP-3, WISP3" ENSG00000112761 "Cellular communication network factor 6" O95389 6 112054075-112069686 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "epididymis: 10.2" "Cell type enriched" "Detected in single" 7 "Cardiomyocytes: 2.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 49 "RT4: 12.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA064196 Supported Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 15: RT4 - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA064196: AB_2685209" "unprognostic (2.13e-2)" "unprognostic (7.90e-3)" "unprognostic (5.00e-2)" "unprognostic (2.22e-2)" "unprognostic (3.76e-1)" "unprognostic (6.52e-2)" "unprognostic (1.98e-3)" "unprognostic (4.07e-3)" "unprognostic (1.82e-1)" "unprognostic (3.90e-1)" "unprognostic (1.02e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "unprognostic (3.11e-1)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 10.2 0.0 2.3 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823883 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.6;lymphoid tissue: 46.9;retina: 31.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Erythroid cells: 102.1;Extravillous trophoblasts: 92.8;Plasma cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 3.4;white matter: 7.6" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB000114: AB_563675, HPA020626: AB_1847376" "unprognostic (4.02e-2)" "unprognostic (1.93e-1)" "unprognostic (7.66e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "prognostic unfavorable (9.17e-5)" "prognostic unfavorable (4.27e-4)" "unprognostic (3.92e-3)" "unprognostic (2.65e-2)" "prognostic unfavorable (4.43e-6)" "unprognostic (8.38e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (6.07e-2)" "unprognostic (1.59e-1)" 1.5 1.2 2.5 11.4 2.5 38.6 2.5 3.5 4.7 4.3 2.5 9.8 10.1 2.5 0.6 8.4 2.2 1.8 1.3 2.3 2.4 1.5 1.6 1.8 25.0 2.8 2.7 3.8 0.8 0.6 2.7 10.5 2.6 1.9 11.5 31.7 1.8 0.8 0.7 6.7 9.9 4.0 2.6 4.6 4.4 6.2 2.6 46.9 1.2 0.5 24.4 2.9 3.9 3.5 177.1 45.3 120.5 51.8 6.4 16.3 98.8 119.7 52.8 156.7 115.6 99.4 106.5 161.2 31.7 63.8 55.0 58.0 154.2 71.1 128.0 77.8 70.8 129.7 56.0 96.9 1.5 197.0 88.0 4.2 5.3 65.1 38.7 24.7 95.4 84.3 187.9 156.9 126.1 63.8 251.8 113.1 95.5 109.9 49.8 114.1 233.5 78.2 44.8 34.6 51.0 53.8 63.1 76.0 32.4 89.8 63.7 81.9 56.5 72.7 109.3 77.4 115.9 98.0 112.3 181.9 41.5 197.6 82.4 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.9 0.6 0.4 0.0 0.0 0.2 0.1 0.8 0.1 0.0 3.1 0.9 2.5 2.5 3.5 4.7 2.3 2.4 2.8 2.7 2.6 2.6 2.6 3.5 0.8 0.0 1.1 1.6 5.7 2.8 1.5 5.5 1.8 2.9 1.9 1.8 0.8 0.0 1.6 0.0 12.5 47.9 1.9 4.9 0.0 0.7 9.6 0.6 2.7 3.3 1.2 102.1 3.3 0.2 92.8 6.3 9.2 2.1 0.0 18.1 4.2 0.9 25.3 0.0 4.1 7.7 8.2 6.9 3.6 2.1 0.9 3.6 1.8 2.8 0.2 1.2 0.0 4.5 5.2 0.5 3.1 1.2 35.5 3.3 1.8 0.2 2.5 14.2 0.0 0.9 6.0 10.3 17.7 24.0 1.3 8.5 6.3 1.4 19.9 2.1 CCNB1IP1 "C14orf18, HEI10" ENSG00000100814 "Cyclin B1 interacting protein 1" Q9NPC3 14 20311368-20333312 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 381.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.37e-2)" "unprognostic (5.46e-3)" "unprognostic (2.79e-2)" "unprognostic (8.43e-2)" "unprognostic (5.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.88e-2)" "unprognostic (4.87e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.18e-6)" "unprognostic (2.12e-1)" "unprognostic (1.54e-2)" "unprognostic (4.43e-1)" "unprognostic (1.52e-1)" 31.3 20.0 31.7 10.6 32.8 35.5 58.1 31.8 44.3 52.6 38.4 35.3 21.3 43.0 48.4 27.3 53.2 20.8 74.7 31.1 35.3 66.4 74.9 36.9 25.3 34.7 32.7 99.4 45.3 51.3 22.2 31.3 34.9 38.1 30.1 21.2 29.6 24.4 52.2 35.5 24.7 29.9 32.7 20.4 31.0 23.3 31.8 32.0 57.4 63.4 30.7 40.0 41.7 34.4 30.8 24.7 137.5 133.3 68.9 94.1 110.3 37.0 73.6 55.5 72.8 83.2 33.4 106.2 23.9 27.1 55.6 53.8 96.6 69.9 74.3 30.9 82.0 63.1 22.6 79.7 201.7 117.5 56.6 128.8 114.6 39.6 381.3 67.3 42.6 125.7 77.7 82.1 37.0 48.9 68.5 79.3 83.2 66.5 46.6 82.9 67.9 45.5 58.7 44.6 109.0 113.6 25.5 58.5 170.7 75.8 18.7 84.5 18.4 31.6 40.1 38.4 48.8 38.3 51.0 72.6 10.6 97.3 37.1 6.3 4.2 0.1 8.2 1.4 10.9 11.6 9.0 10.3 17.7 9.8 9.2 13.0 0.6 6.0 1.6 18.2 13.3 3.8 31.7 32.8 31.8 44.3 31.1 35.3 34.7 32.7 34.9 32.7 31.8 34.4 22.2 28.9 27.2 16.3 35.5 58.1 74.0 45.5 113.3 4.2 57.0 71.9 30.9 58.6 21.0 23.9 20.9 41.2 27.7 15.1 103.7 31.8 64.2 13.0 37.6 24.9 41.3 34.7 22.2 38.2 70.6 34.5 23.0 20.2 34.9 76.7 20.0 35.3 17.8 1.7 28.5 40.1 28.5 23.3 26.5 92.8 51.6 22.4 51.6 7.5 17.8 46.9 30.9 15.1 19.7 29.3 18.8 44.0 17.4 63.5 21.0 86.5 5.2 17.6 46.0 36.6 31.6 101.0 77.5 67.0 40.1 34.1 28.7 61.1 44.3 51.3 CCND3 ENSG00000112576 "Cyclin D3" P30281 6 41934934-42050357 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 256.6" "Cell type enhanced" "Detected in all" "NK-cells: 555.1;Syncytiotrophoblasts: 236.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 696.3;REH: 651.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000116, HPA042871" Approved Supported Nucleoplasm NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "CAB000116: , HPA042871: " "unprognostic (4.53e-2)" "unprognostic (4.45e-2)" "unprognostic (2.45e-1)" "unprognostic (4.40e-3)" "unprognostic (1.01e-1)" "unprognostic (9.80e-2)" "unprognostic (3.40e-2)" "unprognostic (5.25e-2)" "unprognostic (7.76e-2)" "unprognostic (3.45e-1)" "unprognostic (9.17e-2)" "unprognostic (6.39e-2)" "unprognostic (2.45e-3)" "unprognostic (9.12e-2)" "unprognostic (1.71e-1)" "prognostic favorable (8.08e-6)" "unprognostic (2.11e-1)" 74.3 137.6 84.8 63.1 84.6 220.2 64.8 80.0 94.5 36.9 78.4 45.6 40.6 35.4 15.3 39.6 43.2 34.4 68.1 86.2 88.6 42.4 22.1 102.5 143.3 87.4 82.5 36.0 31.6 23.7 33.3 55.4 84.0 50.4 27.0 10.3 50.4 25.6 18.2 52.3 78.5 28.6 79.7 170.4 66.1 11.1 86.4 256.6 58.7 32.5 83.6 45.4 44.3 80.8 67.7 242.2 24.6 54.8 43.7 88.6 286.1 77.1 43.7 77.7 57.1 45.9 29.7 288.9 127.8 51.9 68.9 40.5 65.8 93.4 39.2 49.2 43.4 458.8 106.6 37.3 94.9 75.9 385.2 84.7 59.8 76.0 27.9 23.5 96.6 188.3 236.7 27.2 111.6 92.0 696.3 354.6 10.9 202.8 51.5 651.8 96.3 32.2 179.1 44.9 83.8 21.8 65.8 83.3 38.6 30.6 51.5 288.4 162.9 86.2 47.9 74.7 88.1 17.9 15.2 458.5 50.4 157.6 53.3 1281.3 246.3 725.1 390.4 294.4 276.5 127.1 266.4 318.1 343.3 180.8 306.4 328.3 339.3 333.2 405.6 221.4 193.0 635.4 84.8 84.6 80.0 94.5 86.2 88.6 87.4 82.5 84.0 79.7 86.4 80.8 102.2 60.9 67.9 31.0 102.9 27.0 95.8 52.3 48.9 19.6 49.9 45.1 26.2 64.3 27.8 20.2 6.2 201.0 227.3 66.4 29.4 20.3 12.8 12.1 10.8 68.3 9.6 133.6 37.1 24.3 82.4 32.3 19.9 11.2 26.6 7.7 70.6 7.2 45.3 11.8 23.7 19.5 50.8 115.7 51.7 9.4 41.3 152.2 37.4 47.8 79.0 40.8 555.1 18.1 9.3 29.9 30.5 51.9 48.7 40.3 18.6 19.8 22.5 16.2 46.0 19.2 31.9 4.3 6.3 21.7 22.6 236.6 195.0 141.6 32.7 52.8 CCNE2 CYCE2 ENSG00000175305 "Cyclin E2" O96020 8 94879770-94896678 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.6;Oligodendrocytes: 34.5;Spermatocytes: 77.7;Spermatogonia: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 5.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 101.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007825, CAB019374" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB007825: AB_598148, CAB019374: " "unprognostic (1.80e-2)" "unprognostic (4.81e-2)" "unprognostic (7.49e-2)" "unprognostic (2.08e-2)" "unprognostic (2.36e-1)" "prognostic favorable (5.87e-4)" "unprognostic (8.37e-4)" "prognostic unfavorable (8.77e-4)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.64e-2)" "unprognostic (1.04e-2)" "unprognostic (7.01e-12)" "unprognostic (1.81e-2)" "unprognostic (1.50e-1)" "unprognostic (1.06e-2)" "unprognostic (3.03e-1)" 2.0 0.6 3.7 6.9 8.3 37.0 2.2 9.0 7.7 1.7 0.3 5.4 3.6 1.8 0.1 4.7 0.6 2.4 1.4 3.2 5.4 0.5 2.3 1.8 10.9 9.9 8.1 1.5 1.8 0.5 0.6 4.3 8.8 1.2 5.7 5.2 1.8 0.2 0.7 5.9 4.3 2.2 7.4 2.3 4.0 14.5 8.0 15.1 1.7 0.7 9.6 2.1 1.5 13.4 47.2 6.2 24.0 15.0 2.9 5.4 16.5 47.3 16.6 29.4 28.9 11.3 20.6 24.5 31.4 20.3 9.1 24.4 19.4 17.5 39.5 17.4 17.5 49.5 26.6 4.2 0.2 20.2 29.0 1.4 1.1 21.4 2.1 6.4 15.5 30.1 21.7 101.5 42.5 14.2 77.8 9.7 8.1 37.4 14.1 54.1 41.7 11.7 8.1 26.4 34.8 14.5 31.8 8.4 5.9 3.0 42.0 21.2 13.0 30.7 20.2 22.9 42.8 19.1 21.1 59.3 24.8 36.1 23.1 0.0 0.2 0.1 0.8 0.2 0.3 0.3 1.1 1.3 0.7 1.0 0.3 0.6 0.6 1.5 0.1 0.0 5.2 0.6 3.7 8.3 9.0 7.7 3.2 5.4 9.9 8.1 8.8 7.4 8.0 13.4 7.5 6.4 1.7 0.7 3.0 4.2 1.6 2.3 6.8 2.9 5.9 8.9 2.5 0.0 1.9 1.8 6.2 7.2 7.2 12.3 0.0 0.2 6.9 1.3 2.7 3.5 0.0 33.6 2.3 0.2 7.8 2.6 4.1 2.9 0.0 2.1 2.5 1.3 4.4 8.4 2.6 4.0 0.0 2.5 1.9 9.0 1.2 4.8 0.0 0.0 0.0 1.0 1.0 1.5 34.5 0.2 2.4 0.4 14.6 1.1 6.3 0.1 1.1 4.7 6.6 2.6 4.3 77.7 26.2 9.5 3.8 1.9 7.5 1.2 3.3 0.8 CCNJL FLJ14166 ENSG00000135083 "Cyclin J like" Q8IV13 5 160249083-160345396 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 23.4;Intestinal goblet cells: 28.5;Paneth cells: 26.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 18.6" "Group enriched" "Detected in some" 17 "neutrophil: 12.7;NK-cell: 4.2" "Group enriched" "Detected in many" 85 "granulocytes: 12.7;NK-cells: 4.2" "Cell line enhanced" "Detected in many" "HBEC3-KT: 49.8;RT4: 28.0;WM-115: 38.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049970 Approved Approved "Nuclear speckles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear speckles" "HPA049970: AB_2680974" "unprognostic (1.09e-2)" "unprognostic (2.36e-2)" "prognostic favorable (7.31e-4)" "unprognostic (1.50e-3)" "unprognostic (1.79e-1)" "unprognostic (4.31e-2)" "unprognostic (1.60e-4)" "unprognostic (1.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.09e-1)" "unprognostic (2.57e-1)" "unprognostic (1.75e-2)" "unprognostic (6.27e-3)" "unprognostic (6.63e-3)" "unprognostic (2.62e-1)" "prognostic favorable (7.10e-4)" "prognostic favorable (8.02e-4)" 0.9 3.8 1.2 1.6 1.2 1.4 1.3 18.6 3.1 2.6 1.3 7.8 1.3 0.7 0.6 1.0 1.3 0.7 5.7 4.7 1.2 4.0 0.7 7.8 0.4 1.8 2.0 5.4 0.2 0.1 3.8 0.9 2.1 1.4 5.8 1.5 4.8 1.3 0.2 0.5 3.3 0.8 1.4 7.5 7.2 12.2 2.2 2.6 4.2 2.6 1.1 3.4 1.5 1.3 3.9 20.8 16.4 0.2 0.0 0.0 0.0 0.0 0.3 1.9 0.8 7.9 16.8 0.0 13.2 0.2 13.9 5.9 2.3 49.8 1.3 0.0 0.3 6.0 7.3 6.8 0.2 0.0 0.2 0.0 4.2 2.7 11.9 9.9 12.7 5.8 0.1 0.0 5.3 2.7 0.0 12.1 11.5 0.0 7.8 3.4 4.6 1.7 12.6 28.0 4.7 10.5 2.9 3.7 17.1 6.2 9.9 1.1 14.9 2.6 13.8 0.0 9.8 0.0 0.0 0.0 0.0 0.0 38.3 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 4.2 0.0 0.0 0.0 0.2 1.2 1.2 18.6 3.1 4.7 1.2 1.8 2.0 2.1 1.4 2.2 1.3 0.6 22.4 23.4 9.4 0.0 0.3 1.8 3.8 0.0 0.7 1.0 2.3 4.8 0.0 6.8 3.7 0.0 0.0 4.5 4.4 5.9 2.7 1.0 0.5 1.4 2.6 2.4 0.0 0.7 0.2 0.0 1.2 1.1 1.4 1.3 11.5 2.2 0.2 0.1 0.0 9.3 28.5 8.2 0.3 0.3 3.6 2.1 2.1 5.4 2.8 0.6 8.3 14.4 1.5 0.7 1.7 26.8 2.6 0.5 1.3 4.3 0.2 1.5 0.1 0.0 0.7 1.9 0.5 10.0 0.4 0.4 0.0 2.2 11.2 4.6 2.4 CCNL1 ania-6a ENSG00000163660 "Cyclin L1" Q9UK58 3 157146508-157160760 "Predicted intracellular proteins" "Transcription, Transcription regulation" Cyclin Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057911 Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear bodies" "HPA057911: AB_2683553" "unprognostic (1.03e-2)" "unprognostic (3.66e-2)" "unprognostic (1.38e-1)" "unprognostic (6.90e-3)" "unprognostic (1.79e-1)" "unprognostic (6.58e-2)" "unprognostic (3.16e-3)" "unprognostic (7.50e-2)" "unprognostic (5.54e-3)" "unprognostic (3.37e-1)" "unprognostic (3.06e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.01e-6)" "unprognostic (3.71e-1)" "unprognostic (2.24e-1)" "unprognostic (5.62e-2)" "prognostic favorable (6.96e-7)" 52.1 25.2 12.4 11.6 12.9 56.6 27.3 14.2 21.2 21.9 12.6 22.5 13.5 19.4 5.7 22.1 30.5 13.5 23.1 13.0 13.2 31.8 45.3 30.2 14.1 15.1 12.8 31.2 33.5 8.3 21.8 10.3 13.1 23.8 6.6 5.3 18.7 6.2 21.3 25.3 29.7 9.1 11.9 35.6 29.1 9.1 13.0 20.0 23.7 10.3 9.8 19.4 22.9 14.7 19.2 11.4 16.8 11.6 16.1 10.9 16.0 12.0 14.4 13.9 13.0 19.7 14.8 20.3 10.0 8.9 9.7 14.7 12.4 14.6 12.8 18.2 14.1 12.6 12.2 17.2 13.2 8.8 7.7 13.3 25.1 13.2 17.7 13.9 11.1 11.4 8.7 12.7 10.2 13.8 17.8 16.7 13.9 14.7 12.5 16.2 13.6 31.7 8.9 11.4 8.9 16.5 9.1 8.4 26.1 12.5 8.7 26.1 9.1 12.8 7.1 13.8 15.9 25.3 21.5 26.7 12.8 13.1 12.6 5.9 10.3 16.0 13.5 8.4 14.1 13.4 12.5 14.0 13.1 15.2 17.1 14.2 28.6 17.4 11.3 14.0 15.4 8.2 12.4 12.9 14.2 21.2 13.0 13.2 15.1 12.8 13.1 11.9 13.0 14.7 367.4 218.0 392.4 33.0 222.5 268.0 499.2 203.8 310.7 73.7 279.3 247.0 54.3 177.3 259.0 68.0 133.5 139.2 253.6 389.6 23.5 189.4 41.0 379.7 426.5 287.1 247.7 86.5 30.6 127.8 152.9 302.7 268.1 761.2 222.2 281.6 167.8 90.4 164.6 40.4 32.3 294.6 154.6 241.5 251.4 20.9 128.0 292.5 140.5 42.2 160.1 69.5 122.6 35.7 66.3 143.2 378.2 75.2 258.5 408.2 415.6 21.2 188.9 183.3 131.5 460.0 276.4 46.5 25.0 252.6 276.9 209.1 282.8 182.6 244.1 503.2 CCNL2 "ania-6b, CCNM, CCNS, HLA-ISO, PCEE, SB138" ENSG00000221978 "Cyclin L2" Q96S94 1 1385711-1399335 "Predicted intracellular proteins" "Transcription, Transcription regulation" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053137 Supported Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA053137: AB_2682053" "unprognostic (3.08e-2)" "unprognostic (2.60e-1)" "unprognostic (1.14e-2)" "unprognostic (1.45e-1)" "unprognostic (8.97e-2)" "unprognostic (1.59e-3)" "unprognostic (2.06e-1)" "unprognostic (3.91e-2)" "unprognostic (1.67e-2)" "unprognostic (1.15e-1)" "unprognostic (7.08e-3)" "unprognostic (2.91e-2)" "prognostic unfavorable (1.12e-6)" "unprognostic (4.61e-2)" "unprognostic (6.17e-2)" "unprognostic (3.71e-1)" "prognostic favorable (1.46e-7)" 65.1 79.9 16.3 29.6 17.5 33.3 74.0 24.1 21.5 101.8 27.8 76.9 36.0 88.7 30.9 67.2 86.6 26.4 57.9 16.9 14.2 65.6 100.5 62.1 32.2 16.9 15.7 104.3 90.2 31.7 73.4 34.4 18.4 76.0 22.8 22.9 78.1 31.9 49.7 73.7 75.8 26.6 15.7 62.1 71.3 31.1 17.0 31.6 91.4 18.4 28.1 77.0 82.5 26.6 30.1 24.5 72.5 29.7 39.2 63.9 37.1 63.8 33.8 32.1 31.6 27.5 57.9 30.6 35.3 42.8 27.7 68.4 26.8 40.9 24.6 14.7 68.9 38.4 142.0 43.8 47.8 19.9 42.8 81.1 29.0 31.4 48.5 94.6 34.9 41.0 37.3 32.4 37.6 32.1 25.1 78.7 23.7 21.2 48.5 48.8 17.6 39.1 56.5 37.1 45.4 63.0 40.7 60.6 37.5 42.8 48.8 30.3 60.1 70.8 32.5 29.4 25.2 64.9 12.1 53.7 35.0 50.7 18.5 5.4 6.1 8.5 7.4 4.6 5.0 7.2 7.2 7.9 7.1 9.0 8.3 7.4 5.8 6.6 7.3 6.7 4.3 2.9 16.3 17.5 24.1 21.5 16.9 14.2 16.9 15.7 18.4 15.7 17.0 26.6 66.4 35.3 107.5 76.7 46.6 45.5 36.6 48.3 50.7 31.7 50.8 56.4 37.2 40.0 58.1 29.5 47.9 43.2 48.7 43.1 21.5 30.6 22.4 49.0 82.1 56.0 50.6 26.5 44.7 26.7 33.8 49.9 78.5 55.2 43.1 81.4 37.5 45.6 24.7 60.6 41.2 41.5 52.9 22.9 34.0 14.6 51.3 31.0 32.0 48.7 27.2 35.5 47.4 31.2 52.5 40.2 40.7 32.7 46.7 31.1 33.9 18.4 58.6 39.4 59.2 56.8 59.9 45.1 30.6 40.3 44.0 63.8 46.4 73.6 34.6 39.0 CCSER1 "FAM190A, KIAA1680" ENSG00000184305 "Coiled-coil serine rich protein 1" Q9C0I3 4 90127535-91601913 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 3.6" "Group enriched" "Detected in many" 4 "Excitatory neurons: 1954.8;Inhibitory neurons: 1639.5;Oligodendrocyte precursor cells: 577.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.5;OE19: 2.4;RT4: 1.2;SCLC-21H: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041880, HPA054709" Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA041880: AB_10796461, HPA054709: AB_2682581" "unprognostic (4.03e-4)" "unprognostic (4.21e-3)" "unprognostic (6.45e-2)" "unprognostic (2.44e-2)" "unprognostic (3.32e-1)" "unprognostic (3.45e-2)" "unprognostic (5.61e-2)" "unprognostic (8.13e-2)" "unprognostic (1.24e-1)" "unprognostic (5.36e-3)" "unprognostic (2.87e-1)" "unprognostic (2.04e-1)" "unprognostic (2.42e-6)" "unprognostic (1.21e-1)" "unprognostic (1.14e-1)" "unprognostic (1.64e-4)" "unprognostic (6.94e-2)" 0.2 1.3 1.5 0.2 1.5 0.7 0.9 2.1 2.6 0.1 0.1 0.3 0.3 0.3 0.3 0.2 0.8 0.3 1.0 2.1 0.7 1.1 0.1 0.2 0.4 0.4 0.2 0.1 0.6 0.3 0.4 0.1 0.5 0.5 0.2 3.6 1.1 0.3 0.0 0.5 0.4 0.2 0.1 0.4 0.4 2.6 0.9 0.3 0.9 0.1 0.2 0.6 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.5 0.1 0.4 0.4 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 2.4 0.2 0.0 0.0 0.1 0.1 1.2 1.3 0.4 0.0 0.4 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.5 2.1 2.6 2.1 0.7 0.4 0.2 0.5 0.1 0.9 1.9 12.4 6.4 3.2 72.5 21.4 4.5 11.9 0.1 15.9 23.7 5.5 4.4 11.1 1.5 2.2 3.7 177.2 3.6 0.2 9.0 9.8 1.2 261.8 2.4 0.4 3.1 3.5 2.5 1954.8 3.5 5.6 0.9 23.4 4.8 5.1 0.8 3.3 0.2 1.0 5.0 1639.5 10.9 2.0 0.6 8.6 339.4 3.1 5.7 1.8 89.0 2.4 2.6 0.0 577.5 33.7 4.9 7.7 1.2 5.7 8.8 13.0 2.6 0.2 78.8 6.6 0.4 0.5 5.6 4.7 1.6 2.3 1.8 0.5 0.3 5.1 14.9 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD160 "BY55, NK1, NK28" ENSG00000117281 "CD160 molecule" O95971 1 145719471-145739288 "CD markers, Predicted secreted proteins" "Adaptive immunity, Angiogenesis, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.5" "Cell type enriched" "Detected in some" 6 "NK-cells: 410.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 107.6;MAIT T-cell: 44.5;memory CD8 T-cell: 72.9;naive CD8 T-cell: 82.8;NK-cell: 85.9" "Group enriched" "Detected in all" 8 "NK-cells: 85.9;T-cells: 107.6" "Cell line enhanced" "Detected in some" "HeLa: 2.2" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (6.54e-4)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.33e-1)" "unprognostic (3.40e-2)" "unprognostic (1.35e-1)" "unprognostic (8.25e-3)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (2.24e-2)" "unprognostic (7.49e-3)" "unprognostic (3.48e-5)" "unprognostic (4.05e-2)" "unprognostic (2.03e-1)" "unprognostic (2.89e-2)" "unprognostic (2.92e-4)" 0.5 0.3 1.0 1.0 0.9 5.2 0.6 2.9 0.8 0.8 0.9 1.6 4.7 0.7 0.4 0.4 0.6 1.0 1.5 0.8 0.2 0.4 5.0 1.4 3.6 0.4 0.3 0.4 0.4 0.0 0.5 0.4 0.3 0.5 1.0 1.4 1.5 0.5 0.8 1.1 4.5 0.1 0.1 13.5 0.8 0.5 0.6 0.3 0.4 0.1 1.5 0.9 0.5 0.6 0.5 0.4 0.6 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.5 0.0 0.0 0.6 0.0 0.1 0.0 1.3 0.6 1.2 2.2 0.5 0.0 0.8 1.2 0.0 0.1 0.0 0.1 0.2 0.0 0.6 0.3 0.5 0.0 0.6 0.4 1.5 0.4 0.3 1.1 0.1 0.0 0.4 0.0 0.2 0.4 0.6 0.3 0.5 0.2 0.4 0.5 0.8 0.6 0.5 0.2 0.3 1.1 0.8 0.6 0.2 0.2 0.9 0.1 12.7 0.3 0.3 107.6 0.6 44.5 1.1 1.2 72.9 0.2 1.2 0.7 82.8 5.6 85.9 1.7 1.2 0.0 81.3 1.0 0.9 2.9 0.8 0.8 0.2 0.4 0.3 0.3 0.1 0.6 0.6 1.1 0.0 0.0 0.7 1.0 0.1 0.2 0.1 0.0 1.8 0.6 0.4 0.5 0.0 0.0 0.0 10.4 0.1 59.8 3.1 0.0 0.1 4.4 0.7 0.5 1.0 0.0 6.6 0.5 0.4 0.0 0.9 3.1 0.8 2.5 0.3 3.9 0.4 0.0 6.7 0.4 0.5 0.0 4.6 0.4 11.1 0.0 0.9 0.0 0.0 1.3 0.9 410.9 0.5 0.2 0.0 0.1 0.0 2.7 0.4 0.3 0.2 0.0 2.9 0.0 1.1 0.4 0.1 0.2 0.0 0.1 0.1 44.0 0.3 1.0 0.2 CD164 "DFNA66, MGC-24, MUC-24" ENSG00000135535 "CD164 molecule" Q04900 6 109366514-109382467 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010636 Uncertain "Intracellular and membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA010636: AB_1078447" "unprognostic (1.23e-2)" "unprognostic (1.61e-2)" "unprognostic (3.89e-2)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (1.04e-2)" "unprognostic (1.97e-3)" "unprognostic (1.80e-1)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (8.88e-2)" "unprognostic (1.38e-1)" "unprognostic (7.11e-2)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "unprognostic (3.01e-1)" "unprognostic (1.51e-1)" 260.9 123.6 43.6 119.1 53.6 213.9 211.2 57.4 69.5 151.0 68.9 264.8 252.0 117.0 161.9 95.0 124.8 159.3 91.8 40.6 57.7 298.1 256.8 121.9 137.8 65.3 56.1 126.4 124.1 219.2 89.5 190.1 64.1 146.1 270.5 36.4 303.8 112.7 96.0 89.2 277.6 116.1 52.3 121.0 272.8 113.6 50.7 132.0 360.4 91.7 122.9 154.2 76.0 70.7 130.0 73.0 34.6 242.9 503.0 496.6 235.7 230.8 304.0 213.7 308.0 148.1 194.9 105.7 218.0 261.5 198.0 125.4 136.9 152.7 315.4 220.1 144.5 177.8 72.0 173.9 294.9 209.5 399.0 384.6 279.7 211.3 186.5 270.3 196.9 86.9 178.9 279.9 287.8 141.1 191.5 251.2 52.9 273.1 119.6 126.3 109.0 135.1 292.2 180.5 40.2 80.9 144.6 184.0 348.6 168.0 167.7 265.0 205.6 138.8 99.1 199.5 188.6 96.3 147.4 121.2 244.0 242.8 147.2 349.0 192.3 167.0 166.8 198.6 175.0 126.2 135.2 155.1 189.7 111.0 138.0 150.1 128.5 255.2 197.5 214.1 192.9 413.8 43.6 53.6 57.4 69.5 40.6 57.7 65.3 56.1 64.1 52.3 50.7 70.7 76.5 163.5 78.9 22.5 168.1 200.1 180.2 149.6 128.7 33.8 251.1 123.3 70.9 174.5 153.5 281.4 25.0 244.9 372.7 600.0 93.9 178.8 103.8 111.9 109.2 89.2 166.5 92.8 22.1 136.8 407.2 176.3 175.8 151.2 128.6 76.7 98.2 177.4 311.9 33.7 16.4 427.3 215.7 360.4 223.9 97.3 158.8 237.3 247.3 38.4 147.1 113.3 266.8 15.6 83.1 177.6 430.0 182.1 173.6 230.3 425.5 348.0 351.2 44.4 124.9 110.0 138.1 160.5 184.4 143.0 231.0 674.5 165.9 87.7 285.0 334.7 CD177 "HNA2A, NB1, PRV1" ENSG00000204936 "CD177 molecule" 19 43353686-43363172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9;intestine: 164.6" "Group enriched" "Detected in some" 5 "Distal enterocytes: 632.4;Paneth cells: 314.8" "Cancer enhanced" "Detected in many" "prostate cancer: 27.6" "Group enriched" "Detected in many" 4 "cerebellum: 3.6;cerebral cortex: 7.7;pons: 2.3" "Immune cell enriched" "Detected in some" 7 "neutrophil: 8.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 98.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041820, HPA046601, HPA077640" Enhanced "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041820: AB_2677691, HPA046601: AB_2679716, HPA077640: " "unprognostic (4.32e-2)" "prognostic favorable (3.66e-4)" "unprognostic (1.04e-2)" "unprognostic (2.04e-3)" "unprognostic (1.61e-1)" "unprognostic (3.89e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (2.05e-1)" "unprognostic (1.45e-1)" "unprognostic (8.38e-2)" "unprognostic (1.90e-2)" "unprognostic (2.45e-1)" "unprognostic (2.70e-1)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (1.24e-1)" 4.8 0.4 0.1 7.2 0.3 285.9 1.3 3.6 7.7 6.0 3.7 155.2 0.3 0.4 0.2 2.2 2.3 0.2 2.2 0.3 0.1 1.9 2.6 20.6 0.2 0.3 1.0 0.3 1.1 0.0 2.9 1.6 2.3 64.8 164.6 0.1 1.8 0.2 0.7 0.4 0.7 3.0 0.3 64.4 1.4 0.2 0.4 1.4 0.7 0.8 10.4 2.1 5.4 0.5 2.1 0.0 0.0 0.0 0.0 0.0 0.3 1.0 1.3 0.6 0.6 0.0 0.0 0.1 2.4 0.6 1.7 0.2 0.1 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 1.2 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.4 1.2 0.0 0.2 0.0 0.0 98.0 1.4 0.3 0.7 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 1.0 0.3 2.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 1.2 0.0 0.7 0.0 0.1 0.3 3.6 7.7 0.3 0.1 0.3 1.0 2.3 0.3 0.4 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.1 0.0 0.0 0.0 0.0 632.4 0.0 0.5 0.4 0.2 0.1 0.0 8.4 3.6 0.0 0.2 0.0 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.2 87.2 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 314.8 0.0 0.1 29.2 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 28.0 0.2 CD1E ENSG00000158488 "CD1e molecule" P15812 1 158353696-158357553 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 69 "lymphoid tissue: 962.6" "Cell type enriched" "Detected in some" 13 "Langerhans cells: 549.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 14 "myeloid DC: 62.5" "Lineage enriched" "Detected in many" 14 "dendritic cells: 62.5" "Cell line enriched" "Detected in some" 43 "MOLT-4: 1276.2" "Not detected" "Not detected" "HPA057769, HPA070634" Uncertain Supported "Nucleoli,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" Nucleoli "HPA057769: AB_2683522, HPA070634: " "unprognostic (7.94e-3)" "unprognostic (1.85e-5)" "unprognostic (1.47e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.33e-1)" "unprognostic (1.54e-3)" "unprognostic (1.24e-1)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (8.55e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (2.49e-1)" "unprognostic (8.50e-2)" "unprognostic (2.45e-1)" 0.7 0.5 0.0 4.4 0.0 0.0 1.8 0.0 0.0 2.1 0.0 2.1 2.2 1.1 0.4 7.9 0.9 4.8 1.0 0.0 0.0 0.8 1.5 3.1 6.4 0.0 0.0 0.6 0.3 0.5 0.1 0.0 0.0 1.1 5.6 0.0 1.5 0.6 0.4 13.9 2.8 0.9 0.0 5.1 4.7 0.5 0.0 962.6 0.8 0.2 9.9 2.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 29.8 0.1 0.0 0.0 0.5 1276.2 0.0 0.3 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 2.5 0.2 0.0 0.0 0.0 62.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.2 0.5 0.0 0.8 8.4 0.0 0.0 0.6 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 0.7 0.0 0.0 1.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 4.8 549.5 0.0 0.0 41.7 8.8 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.5 0.0 7.1 0.1 0.7 0.0 0.0 0.0 CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 249.8" "Group enriched" "Detected in many" 6 "dendritic cells: 158.3;NK-cells: 178.2;T-cells: 476.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 421.8;MAIT T-cell: 403.1;memory CD4 T-cell: 610.2;memory CD8 T-cell: 714.1;naive CD4 T-cell: 316.3;naive CD8 T-cell: 486.2;NK-cell: 1108.0;T-reg: 655.2" "Group enriched" "Detected in all" 10 "NK-cells: 1108.0;T-cells: 714.1" "Group enriched" "Detected in some" 25 "HDLM-2: 224.1;JURKAT: 145.8;MOLT-4: 166.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: AB_442057, HPA003883: AB_1846263" "prognostic favorable (4.36e-4)" "prognostic favorable (1.47e-4)" "unprognostic (3.34e-3)" "prognostic favorable (1.69e-5)" "unprognostic (1.52e-1)" "prognostic favorable (7.46e-5)" "unprognostic (9.32e-3)" "unprognostic (1.61e-2)" "prognostic favorable (3.97e-5)" "prognostic favorable (7.72e-4)" "unprognostic (4.18e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (4.82e-6)" "unprognostic (6.16e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-2)" "unprognostic (7.63e-3)" 4.6 4.6 0.6 51.3 0.7 11.4 7.6 0.6 1.0 5.8 0.8 13.9 17.2 3.7 2.8 8.4 4.2 16.8 2.6 0.5 0.8 2.5 7.8 21.0 119.6 1.7 0.7 2.8 2.9 0.9 0.7 1.0 1.1 5.2 16.0 0.0 8.6 2.3 1.4 3.5 28.4 4.4 1.0 44.1 24.1 1.8 1.0 249.8 3.8 1.7 79.1 20.8 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.1 0.0 0.4 0.0 0.0 0.0 0.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 145.8 0.1 0.5 0.0 0.0 166.9 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.4 0.0 11.3 5.2 1.6 421.8 3.7 403.1 3.8 610.2 714.1 95.4 2.5 316.3 486.2 14.1 1108.0 2.8 21.0 655.2 565.1 0.6 0.7 0.6 1.0 0.5 0.8 1.7 0.7 1.1 1.0 1.0 1.1 5.0 3.2 17.5 0.0 12.3 5.0 0.4 0.0 2.2 0.0 4.0 4.7 2.1 0.0 2.5 3.7 0.0 0.1 158.3 0.2 0.0 0.5 23.5 1.1 1.0 2.9 3.0 24.0 0.0 0.0 0.0 2.5 10.7 0.9 5.1 0.0 8.2 1.5 0.6 0.0 0.0 0.0 0.0 10.9 16.6 7.8 0.6 19.1 1.8 1.0 15.5 0.0 178.2 0.0 0.0 0.0 0.0 0.4 42.3 0.1 0.0 1.7 0.0 0.0 0.0 2.9 4.1 0.3 0.2 0.4 3.7 0.0 476.8 0.0 0.5 0.2 CD200 "MOX1, MOX2, MRC, OX-2" ENSG00000091972 "CD200 molecule" P41217 3 112332347-112362812 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 97.4;Excitatory neurons: 54.5;Inhibitory neurons: 55.7;Syncytiotrophoblasts: 75.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 30.7;naive B-cell: 83.6" "Lineage enriched" "Detected in many" 23 "B-cells: 83.6" "Cell line enhanced" "Detected in some" "AF22: 75.9;HHSteC: 27.2;NTERA-2: 47.7;REH: 42.4;SK-MEL-30: 29.8;WM-115: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031149 Approved NA NA 26000 "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA031149: AB_10600694" "unprognostic (1.84e-1)" "unprognostic (5.08e-2)" "unprognostic (1.79e-1)" "unprognostic (2.03e-3)" "unprognostic (4.97e-1)" "unprognostic (1.21e-2)" "unprognostic (9.29e-2)" "unprognostic (2.25e-2)" "unprognostic (3.06e-1)" "unprognostic (3.14e-2)" "unprognostic (1.21e-2)" "unprognostic (1.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.06e-2)" "unprognostic (2.80e-1)" "unprognostic (4.49e-2)" "unprognostic (1.22e-2)" 25.3 12.1 27.7 15.6 27.3 2.4 11.6 13.2 34.0 20.1 2.9 6.7 3.3 28.4 7.1 8.9 26.7 13.1 9.3 27.9 41.3 8.5 1.0 9.6 26.1 11.9 16.3 11.6 4.9 10.5 26.8 28.2 18.8 12.1 8.2 15.1 9.0 16.5 1.8 4.4 6.9 18.3 15.1 6.2 5.2 2.9 30.4 23.6 18.9 3.6 24.9 27.5 5.9 18.3 0.0 0.0 75.9 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.1 0.2 4.1 0.0 0.9 0.1 8.2 0.4 0.2 0.2 0.5 0.0 0.3 0.4 27.2 0.0 0.1 0.5 0.2 1.6 0.2 0.2 10.8 0.0 0.1 0.7 0.2 0.0 1.2 0.0 47.7 0.0 0.0 42.4 0.1 0.5 0.6 0.1 19.9 23.0 0.0 0.4 29.8 14.0 0.0 0.3 0.1 0.3 2.6 0.0 0.2 0.1 0.1 0.0 0.6 0.2 83.7 3.6 0.4 0.3 0.3 0.1 3.5 30.7 2.0 0.6 1.3 83.6 2.1 1.3 1.7 1.6 0.3 2.8 1.0 3.4 27.7 27.3 13.2 34.0 27.9 41.3 11.9 16.3 18.8 15.1 30.4 18.3 15.2 3.2 9.1 10.7 27.8 4.2 12.6 0.3 0.0 26.8 0.7 13.0 0.8 1.5 1.3 1.8 0.0 3.0 1.6 0.8 0.0 0.3 25.1 20.6 4.2 97.4 38.4 0.8 54.5 0.0 12.1 13.0 3.1 41.0 2.5 0.7 1.4 0.0 1.0 3.3 55.7 8.1 0.0 0.3 6.1 30.3 0.3 1.1 8.8 6.5 14.0 7.1 0.0 29.7 38.5 0.2 10.7 0.0 1.9 15.4 0.9 0.3 2.7 2.5 0.0 13.1 2.6 0.6 0.4 0.7 3.3 75.9 2.9 9.3 7.1 21.6 CD200R1 "CD200R, HCRTR2, MOX2R, OX2R" ENSG00000163606 "CD200 receptor 1" Q8TD46 3 112921205-112975103 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 14.8;granulocytes: 15.2;Hepatic stellate cells: 14.6;Hofbauer cells: 31.8;Langerhans cells: 19.9;T-cells: 12.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "basophil: 234.9" "Lineage enriched" "Detected in all" 10 "granulocytes: 234.9" "Cell line enriched" "Detected in some" 8 "HEL: 25.5" HPA068512 Supported "Plasma membrane" "Intracellular and membrane" NA NA 2000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA068512: AB_2732784" "unprognostic (1.49e-2)" "unprognostic (1.06e-2)" "unprognostic (2.55e-1)" "unprognostic (1.97e-2)" "unprognostic (1.53e-1)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.06e-3)" "unprognostic (8.30e-2)" "unprognostic (1.85e-1)" "unprognostic (7.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.08e-5)" "unprognostic (1.77e-1)" "unprognostic (7.84e-3)" "unprognostic (1.25e-1)" "unprognostic (5.12e-3)" 1.7 1.2 0.3 3.0 0.4 1.7 1.4 0.2 0.6 0.7 0.7 1.5 1.6 0.7 0.3 3.8 0.5 1.9 0.6 0.4 0.3 0.5 2.4 1.9 4.4 0.3 0.2 0.3 0.5 0.5 0.2 5.3 0.3 0.6 2.3 0.1 0.6 0.7 0.1 2.6 2.0 1.1 0.2 7.9 1.5 0.7 0.2 3.4 0.5 0.9 4.6 1.9 0.5 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.3 25.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 1.2 0.0 234.9 2.9 53.6 4.0 1.3 7.0 9.9 13.8 7.9 22.9 5.6 13.4 6.1 0.8 2.5 0.4 0.5 4.3 5.2 0.3 0.4 0.2 0.6 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.2 0.2 0.0 1.1 1.6 4.4 1.9 0.1 0.0 14.8 0.0 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.3 1.9 0.0 0.0 0.0 0.1 1.0 0.1 0.5 0.0 4.0 5.7 0.0 0.2 0.9 0.0 0.1 15.2 0.0 14.6 0.1 31.8 0.0 2.2 0.0 0.0 6.7 19.9 0.0 0.0 9.1 5.4 5.6 5.2 0.0 0.0 1.0 0.7 0.1 0.0 0.0 2.7 0.1 0.0 0.1 1.2 0.0 0.0 0.3 0.4 0.8 0.3 5.8 0.9 0.7 12.4 0.0 0.0 0.2 CD22 "SIGLEC-2, SIGLEC2" ENSG00000012124 "CD22 molecule" P20273 19 35319261-35347361 "CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 141.3;lymphoid tissue: 230.2;ovary: 132.8" "Group enriched" "Detected in many" 7 "B-cells: 143.6;granulocytes: 95.8;Granulosa cells: 51.3;Oligodendrocytes: 91.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 24 "memory B-cell: 97.6;naive B-cell: 120.3" "Lineage enriched" "Detected in many" 26 "B-cells: 120.3" "Cell line enhanced" "Detected in some" "Daudi: 280.6;REH: 83.8;U-698: 219.9;WM-115: 50.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002418, HPA024353, HPA066523" Enhanced NA NA 13000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB002418: AB_563529, HPA024353: AB_10600695, HPA066523: " "unprognostic (2.80e-3)" "unprognostic (3.99e-2)" "unprognostic (6.79e-3)" "unprognostic (9.17e-2)" "unprognostic (3.07e-1)" "unprognostic (6.45e-3)" "unprognostic (3.79e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (2.47e-1)" "unprognostic (1.75e-3)" "unprognostic (1.98e-2)" "unprognostic (1.48e-2)" "unprognostic (9.05e-2)" "unprognostic (3.04e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" 2.7 5.5 39.2 75.3 66.8 13.6 1.7 42.8 58.4 2.7 17.8 4.9 2.3 3.7 2.5 2.2 30.9 4.1 1.3 42.7 53.2 2.1 1.5 7.4 219.2 63.3 53.8 132.8 0.6 0.7 2.1 1.8 60.3 2.9 6.4 0.0 3.5 1.1 0.2 0.3 53.4 2.1 37.8 161.6 7.0 3.8 55.8 11.4 6.3 0.4 230.2 5.7 1.6 141.3 0.9 1.6 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.1 0.4 0.0 5.1 280.6 5.6 0.3 15.0 0.5 0.0 0.0 0.1 1.5 0.0 0.0 0.2 2.2 0.1 0.3 12.4 0.0 0.0 0.2 4.1 0.1 0.0 0.0 1.5 0.1 2.6 0.5 0.1 0.0 0.1 0.4 0.4 83.8 0.3 0.2 0.0 0.0 0.0 0.0 0.3 1.4 6.6 0.2 0.5 0.1 0.3 2.6 1.5 0.0 0.0 0.0 0.1 219.9 2.2 0.9 50.1 0.1 0.1 0.1 0.0 1.1 0.0 97.6 0.0 0.0 4.6 120.3 0.0 0.0 1.0 0.2 0.7 3.8 0.0 4.9 39.2 66.8 42.8 58.4 42.7 53.2 63.3 53.8 60.3 37.8 55.8 141.3 1.7 3.2 3.0 0.0 143.6 0.3 0.4 0.0 0.0 0.0 1.0 3.3 0.7 0.0 0.6 0.0 0.0 0.2 4.1 0.1 0.0 0.0 0.6 0.2 0.4 2.1 0.0 2.7 0.3 0.2 1.3 2.8 0.5 0.5 95.8 51.3 3.3 0.2 6.8 0.0 0.3 0.0 0.0 5.6 2.0 0.2 3.7 6.9 1.8 0.0 0.9 0.0 1.0 0.0 91.5 0.2 0.1 0.7 2.3 0.4 0.0 0.2 0.1 0.0 0.0 0.2 0.8 0.4 1.1 0.0 0.4 0.1 4.1 12.2 0.0 0.1 CD226 "DNAM-1, DNAM1, PTA1, TLiSA1" ENSG00000150637 "CD226 molecule" Q15762 18 69831158-69961803 "CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 20.2;parathyroid gland: 62.4" "Cell type enhanced" "Detected in many" "dendritic cells: 52.1;Macrophages: 24.4;Microglial cells: 22.5;NK-cells: 90.6;Oligodendrocytes: 26.6;T-cells: 43.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 36.6;MAIT T-cell: 13.4;memory CD4 T-cell: 28.8;memory CD8 T-cell: 22.5;naive CD4 T-cell: 15.8;naive CD8 T-cell: 17.3;NK-cell: 29.7;T-reg: 11.3" "Group enriched" "Detected in many" 11 "NK-cells: 29.7;T-cells: 36.6" "Group enriched" "Detected in some" 6 "HEL: 100.0;HMC-1: 42.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA015715, HPA015865" Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA No 20000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA015715: AB_1846278, HPA015865: " "unprognostic (1.42e-4)" "unprognostic (1.30e-3)" "unprognostic (9.01e-3)" "unprognostic (3.49e-5)" "unprognostic (4.15e-1)" "unprognostic (9.52e-4)" "unprognostic (3.68e-3)" "unprognostic (2.93e-2)" "unprognostic (3.43e-1)" "unprognostic (3.31e-3)" "unprognostic (8.36e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-3)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (2.27e-1)" "unprognostic (3.58e-2)" 1.1 0.6 1.1 5.7 6.4 4.4 1.5 1.5 2.4 1.1 0.0 1.8 2.3 1.3 0.5 1.6 1.3 3.0 0.5 0.7 2.0 1.5 4.2 4.2 9.7 3.1 3.3 0.9 0.5 62.4 0.6 0.5 3.2 1.0 2.4 1.4 1.5 0.4 0.7 0.3 3.1 1.6 2.2 20.2 3.2 1.2 5.5 6.4 0.7 0.6 7.1 3.1 0.4 3.2 0.0 0.1 0.3 0.3 0.0 0.0 0.1 0.6 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.4 0.2 5.3 0.1 100.0 0.3 0.1 0.0 0.7 42.6 0.0 1.1 0.2 0.6 0.2 0.0 0.9 0.3 9.3 0.4 0.0 0.8 0.4 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.5 0.8 0.3 0.1 0.2 11.5 0.4 0.0 0.3 0.2 0.5 0.3 0.1 1.2 36.6 1.0 13.4 0.8 28.8 22.5 2.9 0.1 15.8 17.3 1.6 29.7 1.3 0.1 11.3 13.2 1.1 6.4 1.5 2.4 0.7 2.0 3.1 3.3 3.2 2.2 5.5 3.2 0.6 3.2 3.6 3.3 3.2 0.0 0.3 0.0 0.0 3.4 0.5 0.8 2.5 0.0 0.7 0.0 0.0 0.1 52.1 0.2 0.0 0.0 8.4 0.9 1.7 1.0 0.0 3.2 4.6 0.4 0.0 1.3 3.1 0.5 13.9 1.3 3.3 0.4 1.6 0.0 3.1 0.1 0.0 16.7 2.7 8.2 0.9 24.4 0.0 22.5 14.7 0.8 90.6 2.0 26.6 0.2 0.1 0.7 13.4 0.3 0.0 0.3 1.5 3.6 0.0 1.8 0.6 0.4 0.8 0.0 0.4 0.0 43.2 0.5 0.1 0.2 CD24 CD24A ENSG00000272398 "CD24 molecule" P25063 6 106969831-106975627 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 1630.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1572.7;Distal tubular cells: 1590.6;Exocrine glandular cells: 3454.1;Glandular and luminal cells: 1441.8;Pancreatic endocrine cells: 1694.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 28 "eosinophil: 86.2;memory B-cell: 61.1;naive B-cell: 39.7" "Group enriched" "Detected in many" 237 "B-cells: 61.1;granulocytes: 86.2" "Cell line enhanced" "Detected in many" "NTERA-2: 989.4;RPTEC TERT1: 4702.6;RT4: 931.5;SK-BR-3: 1352.5" "HPA045879, CAB078471" Approved Enhanced Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "CAB078471: AB_10983158, HPA045879: AB_2732523" "prognostic unfavorable (2.44e-5)" "unprognostic (6.64e-2)" "prognostic favorable (3.29e-4)" "unprognostic (1.87e-1)" "unprognostic (1.41e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (7.58e-4)" "unprognostic (2.32e-1)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (2.28e-2)" "unprognostic (1.51e-1)" "unprognostic (5.10e-2)" "unprognostic (2.92e-1)" "unprognostic (1.16e-1)" "unprognostic (2.01e-1)" "unprognostic (3.13e-1)" 7.1 61.9 23.3 139.1 28.8 704.5 468.1 6.4 30.0 288.0 36.7 1071.8 89.0 181.5 229.6 1456.5 242.9 874.3 5.1 45.0 29.2 775.6 30.2 61.6 77.8 26.6 26.0 2.2 1383.4 2.5 12.5 151.7 17.2 148.8 740.8 2.6 952.4 546.9 1.4 77.2 69.8 117.7 19.5 29.6 601.7 4.9 38.6 15.2 1630.2 1.1 445.0 168.9 468.3 50.7 363.2 225.2 3.9 28.6 0.7 0.3 405.8 0.4 2.6 2.0 1.2 3.3 1.9 35.4 106.0 0.1 14.6 730.6 124.1 275.6 1.5 1.0 1.7 1.0 254.2 16.3 0.2 5.1 1.8 2.1 316.1 3.6 18.0 16.9 1.6 1.4 8.3 0.8 6.6 465.6 2.4 2.6 989.4 800.1 85.6 846.8 0.5 3.5 4702.6 931.5 612.4 448.7 250.0 1352.5 1.4 437.1 635.6 2.1 1.6 0.8 4.0 3.1 11.8 1.0 2.0 475.2 5.0 2.9 1.6 0.3 0.1 86.2 0.0 0.0 0.0 61.1 0.0 0.0 0.0 39.7 0.0 0.1 2.1 0.1 0.3 0.1 0.0 2.0 23.3 28.8 6.4 30.0 45.0 29.2 26.6 26.0 17.2 19.5 38.6 50.7 10.2 157.0 83.5 0.7 157.5 0.0 70.4 0.0 7.4 5.8 1109.4 325.4 1.5 1112.3 98.4 1302.1 2.1 749.2 13.7 1572.7 1590.6 1274.1 22.5 1237.6 254.2 38.6 575.4 5.3 0.6 3454.1 885.0 29.9 567.2 1441.8 10.8 0.6 97.5 9.7 70.8 0.0 5.7 463.6 0.0 7.6 0.0 53.4 10.2 17.6 0.0 1.0 32.6 1.0 0.0 0.0 0.1 1694.3 865.2 2.2 1.0 810.2 12.3 538.5 376.8 0.7 6.6 2.9 18.1 0.6 7.2 587.7 0.0 558.3 28.1 0.0 932.8 1043.7 CD276 "B7-H3, B7H3, B7RP-2" ENSG00000103855 "CD276 molecule" Q5ZPR3 15 73683966-73714514 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 215.6;Hofbauer cells: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 175.0;U-2197: 231.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009285, HPA017139, CAB017826" Enhanced Approved Vesicles NA NA 16000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "CAB017826: , HPA009285: AB_1078258, HPA017139: AB_1845246" "unprognostic (1.05e-1)" "unprognostic (4.74e-3)" "unprognostic (4.57e-3)" "unprognostic (9.62e-2)" "unprognostic (1.26e-2)" "unprognostic (5.50e-3)" "prognostic unfavorable (9.81e-4)" "unprognostic (2.57e-3)" "unprognostic (1.89e-1)" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.17e-1)" "unprognostic (9.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.34e-3)" 24.1 19.1 6.6 12.9 4.3 0.7 15.3 0.4 6.5 22.2 15.6 11.4 11.0 20.2 4.3 5.8 10.0 18.2 14.8 4.2 5.7 5.4 11.8 11.6 3.6 5.9 6.7 13.4 15.3 4.3 6.1 26.2 4.1 16.7 4.2 4.6 15.0 9.6 5.0 16.2 8.4 10.8 2.4 9.0 10.9 6.0 7.5 1.6 8.5 2.2 1.6 14.6 13.0 6.7 43.7 44.6 32.5 82.8 57.7 35.0 102.8 47.5 42.0 33.4 30.4 85.3 90.1 0.6 77.7 39.5 64.1 175.0 31.7 39.9 4.4 30.6 76.3 2.8 47.6 47.1 20.9 0.7 51.8 32.7 17.9 28.3 15.4 19.7 38.7 0.0 15.0 0.8 6.2 66.0 0.3 2.3 84.9 8.6 35.9 0.5 47.9 7.0 27.9 53.8 24.9 59.5 40.1 21.2 88.0 23.0 38.1 26.4 49.8 68.6 60.0 231.6 52.5 0.9 0.8 0.8 114.8 3.4 49.4 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.1 0.0 0.0 6.6 4.3 0.4 6.5 4.2 5.7 5.9 6.7 4.1 2.4 7.5 6.7 4.4 19.2 8.1 6.5 1.2 15.0 11.5 12.5 8.0 20.2 14.1 11.8 9.1 2.8 17.0 11.0 31.3 11.6 0.2 6.7 1.9 48.6 0.9 14.4 26.7 22.0 9.0 0.0 18.4 19.0 215.6 43.7 14.3 31.6 14.7 41.4 4.6 14.6 82.5 10.1 12.9 13.1 4.1 8.8 30.8 2.2 9.9 14.7 24.9 7.5 4.2 8.4 0.0 5.5 1.7 24.7 15.1 17.3 1.7 12.1 3.1 2.7 5.8 27.5 13.1 7.0 32.1 1.8 4.9 3.4 10.2 12.3 1.4 8.4 10.6 8.4 CD300LB "CLM7, TREM5" ENSG00000178789 "CD300 molecule like family member b" A8K4G0 17 74521174-74531475 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 7.8;brain: 16.3;lymphoid tissue: 8.2" "Group enriched" "Detected in some" 4 "dendritic cells: 7.1;Hofbauer cells: 6.2;Kupffer cells: 8.7;Langerhans cells: 6.5;Macrophages: 16.6;monocytes: 13.9" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 5 "cerebral cortex: 16.3" "Immune cell enhanced" "Detected in many" "eosinophil: 75.9" "Group enriched" "Detected in many" 53 "dendritic cells: 25.0;granulocytes: 75.9;monocytes: 31.7" "Group enriched" "Detected in some" 6 "HL-60: 1.7;NB-4: 2.4;THP-1: 1.9;U-937: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060449 Approved "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA060449: " "unprognostic (1.39e-1)" "unprognostic (2.44e-2)" "unprognostic (1.37e-1)" "unprognostic (4.39e-2)" "unprognostic (3.59e-2)" "unprognostic (1.15e-1)" "unprognostic (6.41e-2)" "unprognostic (7.69e-2)" "unprognostic (2.05e-1)" "unprognostic (2.95e-2)" "unprognostic (6.24e-2)" "unprognostic (3.32e-1)" "unprognostic (2.49e-4)" "unprognostic (2.92e-2)" "unprognostic (1.79e-2)" "unprognostic (7.08e-2)" "unprognostic (4.01e-2)" 1.7 0.4 0.1 8.2 0.2 7.8 0.7 0.1 16.3 0.4 0.6 0.7 0.7 0.3 0.0 0.3 0.3 2.1 0.2 0.1 0.2 0.2 0.8 1.7 0.8 0.3 0.3 0.1 0.9 0.1 0.2 0.9 3.1 0.4 0.9 0.0 0.3 0.1 0.3 0.1 1.6 1.8 0.2 3.7 0.6 0.3 1.3 0.6 0.2 0.1 0.9 2.5 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 1.1 0.0 1.5 31.7 75.9 0.1 13.6 0.3 0.0 0.0 0.0 25.0 0.0 0.0 0.2 33.3 0.8 1.9 15.6 0.0 11.8 0.1 0.2 0.1 16.3 0.1 0.2 0.3 0.3 3.1 0.2 1.3 0.4 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.6 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.4 0.2 6.2 0.0 0.0 0.0 0.0 8.7 6.5 0.2 0.0 16.6 0.0 0.0 13.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 CD300LF "CD300f, CLM1, IGSF13, IREM1, NKIR" ENSG00000186074 "CD300 molecule like family member f" Q8TDQ1 17 74694311-74712978 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.0;lung: 17.7;lymphoid tissue: 28.9" "Group enriched" "Detected in some" 5 "granulocytes: 22.8;Hofbauer cells: 20.6;Kupffer cells: 33.2;Macrophages: 47.0;monocytes: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 234.2" "Group enriched" "Detected in many" 43 "dendritic cells: 63.8;granulocytes: 234.2;monocytes: 193.0" "Group enriched" "Detected in some" 6 "THP-1: 25.6;U-937: 48.6" "Low region specificity" "Detected in some" HPA013712 Supported NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA013712: AB_2668874" "unprognostic (6.51e-2)" "unprognostic (1.49e-3)" "unprognostic (3.81e-2)" "unprognostic (4.00e-2)" "unprognostic (8.51e-2)" "unprognostic (6.74e-2)" "unprognostic (1.79e-1)" "unprognostic (3.17e-3)" "unprognostic (1.53e-2)" "unprognostic (1.77e-1)" "unprognostic (9.81e-2)" "unprognostic (2.41e-1)" "unprognostic (1.95e-1)" "unprognostic (9.60e-2)" "unprognostic (4.14e-2)" "unprognostic (7.75e-2)" "unprognostic (4.79e-2)" 1.9 0.6 0.9 13.5 1.1 27.0 0.8 6.2 4.2 1.3 0.7 3.4 3.8 0.6 0.2 0.5 0.7 2.7 0.5 1.0 1.3 0.6 2.2 17.7 8.8 2.6 1.8 0.2 0.5 0.4 0.4 1.7 2.4 0.7 3.5 0.2 0.8 0.5 0.3 0.1 3.6 3.3 1.7 28.9 1.6 0.4 2.8 2.0 0.4 0.8 5.4 3.0 0.4 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 2.2 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 48.6 0.0 48.4 96.3 234.2 0.3 165.3 0.5 0.2 0.1 0.2 63.8 0.2 0.2 0.1 74.7 3.7 193.0 6.7 0.4 44.8 0.9 1.1 6.2 4.2 1.0 1.3 2.6 1.8 2.4 1.7 2.8 3.2 0.1 0.0 6.4 0.0 1.3 0.1 0.0 0.1 0.0 0.4 0.1 0.4 0.2 1.5 3.3 0.0 2.1 0.1 2.7 0.1 0.0 0.0 0.3 0.0 0.0 0.8 0.0 1.7 2.7 0.0 0.2 0.3 0.0 0.0 22.8 0.0 1.1 0.3 20.6 0.0 2.1 0.1 0.0 33.2 0.7 0.2 0.0 47.0 0.0 3.7 39.9 0.0 1.0 0.5 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 CD300LG "CLM9, Trem4" ENSG00000161649 "CD300 molecule like family member g" Q6UXG3 17 43847148-43863639 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 133.6;breast: 111.8;placenta: 58.6" "Cell type enriched" "Detected in some" 11 "Adipocytes: 567.9" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 1400000 "Cluster 11: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.38e-2)" "unprognostic (2.06e-3)" "unprognostic (2.63e-1)" "unprognostic (2.72e-1)" "unprognostic (3.18e-1)" "unprognostic (2.73e-1)" "unprognostic (1.40e-4)" "unprognostic (1.77e-1)" "unprognostic (1.33e-1)" "unprognostic (2.01e-2)" "unprognostic (4.08e-3)" "unprognostic (8.69e-4)" "unprognostic (2.12e-5)" "unprognostic (1.30e-3)" "unprognostic (1.45e-1)" "unprognostic (1.76e-2)" "unprognostic (1.57e-1)" 133.6 2.5 0.1 1.5 0.2 0.2 111.8 0.1 0.2 3.7 0.0 2.5 0.1 4.1 12.7 1.9 4.4 4.5 38.0 0.1 0.1 2.1 1.2 11.3 1.8 0.2 0.3 1.9 2.1 1.1 0.2 58.6 0.2 1.7 0.5 0.0 1.9 2.1 22.1 8.7 2.3 1.1 0.1 2.8 3.1 20.0 0.1 3.4 3.1 47.2 0.2 2.6 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.1 567.9 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.6 0.0 1.8 2.3 3.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.6 0.0 0.0 50.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.3 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.3 1.6 13.1 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.9 0.3 0.0 0.0 0.0 0.7 0.0 13.1 2.3 2.9 0.3 0.7 0.1 0.4 0.0 0.3 0.2 0.0 0.0 CD38 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853232 "Cancer-related genes, CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 63.3" "Cell type enriched" "Detected in many" 4 "Plasma cells: 378.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 18.3" "Group enriched" "Detected in all" 5 "B-cells: 9.9;dendritic cells: 5.8;NK-cells: 18.3" "Cell line enhanced" "Detected in some" "Daudi: 128.0;Karpas-707: 34.7;MOLT-4: 32.6;REH: 26.0;RPMI-8226: 20.9;U-266/70: 26.9;U-698: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "CAB002493: AB_563556, CAB025255: , HPA022132: AB_1846300, HPA052381: AB_2681807" "unprognostic (1.27e-2)" "unprognostic (8.06e-3)" "unprognostic (1.06e-2)" "prognostic favorable (9.68e-4)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (2.74e-1)" "unprognostic (8.51e-2)" "unprognostic (5.87e-2)" "unprognostic (6.15e-6)" "unprognostic (5.23e-1)" "unprognostic (4.34e-1)" "unprognostic (6.63e-6)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (2.12e-2)" "unprognostic (2.13e-1)" 3.1 2.4 2.5 13.1 3.8 13.6 2.0 2.7 2.5 0.7 0.9 4.5 5.8 0.9 1.2 1.1 3.0 1.9 3.8 3.5 6.6 0.8 3.3 6.3 23.4 3.3 5.5 0.7 0.3 0.1 1.8 0.5 3.4 13.2 3.5 0.2 2.6 19.7 21.4 0.3 5.3 1.4 2.8 17.0 3.0 1.0 3.9 63.3 2.0 3.4 18.0 6.8 0.5 4.6 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 128.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 17.0 0.2 34.7 0.0 0.0 32.6 7.9 0.2 0.0 0.0 26.0 0.1 20.9 0.0 0.0 0.2 1.5 0.0 0.2 0.5 0.3 0.1 5.7 0.5 0.0 0.1 0.1 0.0 26.9 0.2 24.3 0.4 6.2 0.3 0.1 1.9 0.1 1.2 2.4 0.3 9.9 1.5 1.2 4.7 7.7 2.4 1.9 1.4 18.3 1.9 5.8 2.4 4.4 2.5 3.8 2.7 2.5 3.5 6.6 3.3 5.5 3.4 2.8 3.9 4.6 0.8 3.2 15.1 86.5 59.7 0.0 0.4 0.6 0.6 0.1 0.1 0.0 1.0 0.0 11.6 0.0 10.4 0.2 33.8 0.2 0.0 0.0 2.5 4.0 1.4 2.7 0.0 78.6 0.4 0.0 0.2 2.7 2.0 0.3 38.2 0.8 2.9 4.3 4.4 0.0 0.4 1.3 0.0 44.3 0.8 0.7 0.0 17.7 7.2 5.6 3.1 0.0 79.3 1.0 1.8 0.0 0.3 0.0 378.4 8.1 0.2 0.1 42.5 0.1 13.1 1.5 7.6 2.9 1.7 1.6 0.0 0.5 26.5 0.0 1.6 0.2 CD3D T3D ENSG00000167286 "CD3d molecule" P04234 11 118339075-118342705 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 30 "lymphoid tissue: 906.7" "Group enriched" "Detected in many" 14 "dendritic cells: 231.0;T-cells: 665.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 52 "gdT-cell: 1462.4;MAIT T-cell: 990.0;memory CD4 T-cell: 1206.1;memory CD8 T-cell: 1368.7;naive CD4 T-cell: 1091.4;naive CD8 T-cell: 1338.9;T-reg: 1660.4" "Lineage enriched" "Detected in all" 66 "T-cells: 1660.4" "Group enriched" "Detected in some" 4 "JURKAT: 621.5;MOLT-4: 1299.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013055, HPA071778" Enhanced Uncertain "Endoplasmic reticulum" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "CAB013055: , HPA071778: " "prognostic favorable (3.00e-4)" "prognostic favorable (8.46e-5)" "unprognostic (1.05e-2)" "prognostic favorable (1.73e-7)" "unprognostic (6.00e-2)" "prognostic favorable (1.70e-4)" "unprognostic (3.82e-1)" "unprognostic (2.40e-2)" "unprognostic (2.24e-3)" "unprognostic (1.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (9.00e-2)" "unprognostic (2.02e-1)" "unprognostic (3.66e-2)" "prognostic favorable (6.16e-4)" 4.1 3.8 0.3 77.5 0.4 28.6 9.9 0.4 1.4 5.2 0.7 18.8 21.7 3.6 5.7 7.6 4.5 15.7 3.7 0.3 0.6 2.3 7.9 20.6 222.7 1.1 0.4 3.2 1.3 0.9 0.8 1.2 0.6 5.9 22.4 0.3 8.3 3.1 2.5 4.0 30.1 3.9 0.7 60.9 23.8 2.4 0.5 906.7 3.8 1.4 166.9 26.7 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 621.5 49.8 0.0 0.0 0.0 1299.8 237.2 1.2 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.2 0.8 0.0 0.5 0.0 1.5 1.1 0.0 0.9 1.1 0.4 0.0 0.1 0.0 10.1 5.3 4.6 1462.4 3.3 990.0 9.6 1206.1 1368.7 5.0 3.7 1091.4 1338.9 25.1 4.2 5.3 6.0 1660.4 1138.7 0.3 0.4 0.4 1.4 0.3 0.6 1.1 0.4 0.6 0.7 0.5 0.8 5.9 6.4 29.6 0.0 18.6 15.3 0.3 0.0 1.8 0.0 5.4 6.7 2.8 7.2 2.6 3.7 0.0 0.4 231.0 0.9 0.0 1.3 0.4 0.8 0.8 5.0 1.2 16.8 0.0 0.0 0.0 8.3 21.4 0.9 12.6 0.0 7.9 3.1 0.6 0.0 0.0 0.2 0.0 14.9 28.4 0.7 0.0 14.2 12.4 1.0 25.0 0.0 32.0 0.0 0.0 0.1 0.2 0.0 21.0 0.3 0.0 3.4 1.5 0.0 0.0 2.5 5.8 0.1 1.2 1.4 11.8 0.3 665.7 0.0 1.1 0.2 CD4 ENSG00000010610 "CD4 molecule" P01730 12 6786858-6820799 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 152.9;lymphoid tissue: 219.3;parathyroid gland: 173.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 278.8;Hofbauer cells: 139.3;Kupffer cells: 247.1;Langerhans cells: 80.1;Macrophages: 109.0;monocytes: 104.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 18 "classical monocyte: 247.3;intermediate monocyte: 241.4;memory CD4 T-cell: 153.4;myeloid DC: 166.3;naive CD4 T-cell: 128.1;non-classical monocyte: 204.2;plasmacytoid DC: 263.8;T-reg: 154.5" "Group enriched" "Detected in many" 20 "dendritic cells: 263.8;monocytes: 247.3;T-cells: 154.5" "Group enriched" "Detected in some" 6 "HEL: 103.2;HL-60: 42.1;NB-4: 60.0;THP-1: 116.2;U-937: 109.7" "Region enriched" "Detected in many" 14 "basal ganglia: 46.2" "Low region specificity" "Detected in many" "CAB000011, HPA004252, HPA004472, CAB068180" Enhanced Approved "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB000011: AB_442062, CAB068180: AB_2665653, HPA004252: AB_1078466, HPA004472: AB_1078465" "unprognostic (1.39e-2)" "unprognostic (1.12e-2)" "unprognostic (2.75e-2)" "prognostic favorable (2.16e-4)" "unprognostic (7.76e-2)" "unprognostic (4.82e-3)" "unprognostic (3.70e-2)" "unprognostic (2.74e-2)" "unprognostic (7.04e-2)" "unprognostic (2.40e-1)" "unprognostic (1.13e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.06e-1)" "unprognostic (4.65e-3)" "unprognostic (9.08e-3)" "unprognostic (2.95e-1)" 45.5 16.2 15.0 82.1 15.4 26.5 14.7 15.5 17.4 20.4 15.8 26.0 18.7 7.9 7.0 15.1 21.3 35.3 10.0 15.1 16.7 10.1 152.9 72.1 119.0 22.9 20.2 8.6 7.6 173.8 6.1 47.4 21.0 7.3 31.0 10.5 8.5 10.3 2.9 12.6 27.4 26.5 19.6 164.4 21.0 7.5 19.6 219.3 8.8 5.7 75.7 41.0 5.8 25.7 0.0 0.0 3.6 0.1 0.1 0.2 0.3 0.1 2.4 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 103.2 0.0 0.6 10.5 42.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 15.4 60.0 1.0 0.0 0.0 0.0 0.2 12.8 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.7 0.1 116.2 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.2 0.1 109.7 0.0 0.8 247.3 1.9 2.0 241.4 6.3 0.5 153.4 0.8 166.3 0.5 128.1 0.7 11.1 2.0 204.2 263.8 154.5 240.6 15.0 15.4 15.5 17.4 15.1 16.7 22.9 20.2 21.0 19.6 19.6 25.7 4.5 0.0 5.2 1.6 5.2 3.4 0.3 0.4 0.0 1.5 2.9 5.8 2.1 8.6 2.1 3.7 0.0 0.9 61.9 0.0 5.9 0.0 0.1 3.5 8.7 9.6 0.0 7.8 0.9 0.4 1.2 3.7 0.0 0.4 7.6 0.4 278.8 34.3 139.3 5.0 0.7 0.0 0.0 247.1 80.1 0.5 16.8 109.0 5.4 29.0 104.5 22.0 6.2 0.5 0.2 0.0 0.0 15.1 2.5 0.2 0.0 3.3 20.3 0.2 13.1 0.7 13.5 0.0 0.2 0.4 2.3 1.2 34.0 0.0 0.0 0.4 CD40 "Bp50, p50, TNFRSF5" ENSG00000101017 "CD40 molecule" P25942 20 46118278-46129863 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Immunity Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 127.5;Basal respiratory cells: 126.0;Langerhans cells: 191.4;monocytes: 242.0;Prostatic glandular cells: 130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 139.4;naive B-cell: 157.9" "Group enriched" "Detected in all" 6 "B-cells: 157.9;monocytes: 43.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 76.0;Daudi: 42.1;EFO-21: 131.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002495, HPA031567, HPA031568, CAB072868" Enhanced "Secreted to blood" NA NA 705000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" "CAB002495: AB_563562, CAB072868: AB_2665719, HPA031567: AB_2673936, HPA031568: AB_2673937" "unprognostic (6.41e-2)" "unprognostic (1.55e-2)" "unprognostic (7.08e-3)" "unprognostic (6.21e-2)" "unprognostic (4.23e-3)" "unprognostic (1.25e-1)" "unprognostic (7.64e-3)" "unprognostic (1.34e-1)" "unprognostic (4.15e-2)" "unprognostic (7.16e-2)" "unprognostic (2.48e-2)" "unprognostic (7.04e-2)" "prognostic unfavorable (4.48e-4)" "unprognostic (1.22e-1)" "unprognostic (4.95e-2)" "unprognostic (1.60e-2)" "unprognostic (2.28e-2)" 25.9 8.4 6.7 34.9 7.0 2.7 20.5 7.6 7.7 19.4 9.4 11.8 12.6 14.4 7.6 12.4 19.7 14.3 16.3 6.6 7.2 26.1 18.3 34.4 57.8 8.0 7.1 24.5 21.9 46.5 9.9 12.4 7.6 23.6 9.6 1.1 24.5 15.4 8.6 17.0 21.8 14.0 7.8 35.1 15.6 3.8 7.3 17.3 20.4 7.1 57.7 32.9 21.0 8.0 26.6 4.1 0.0 12.8 4.7 2.7 5.0 4.9 1.4 3.8 3.6 0.0 76.0 42.1 131.8 0.8 18.7 3.1 2.3 16.2 3.9 29.0 0.0 10.0 0.0 7.5 36.6 0.0 13.0 16.2 6.2 15.3 0.0 0.0 28.3 0.0 3.5 0.0 0.8 0.0 0.0 0.2 1.8 9.3 0.1 1.1 1.0 4.5 32.7 0.3 0.0 0.0 23.1 12.6 0.0 0.0 2.7 14.5 0.0 0.0 41.2 0.0 0.1 0.1 0.1 29.2 9.6 5.0 0.1 4.0 28.0 0.4 4.8 43.3 3.5 139.4 2.6 2.0 16.1 157.9 5.0 3.7 2.8 2.9 32.1 8.3 4.1 20.0 6.7 7.0 7.6 7.7 6.6 7.2 8.0 7.1 7.6 7.8 7.3 8.0 68.8 12.8 15.0 6.5 127.5 43.6 63.3 126.0 30.1 1.2 3.8 10.0 3.9 30.0 32.9 14.7 0.0 0.4 7.3 1.5 0.0 68.4 9.0 1.3 2.4 61.5 1.2 5.2 0.9 29.7 3.2 37.9 11.7 3.3 3.8 0.6 55.3 17.0 40.5 0.0 0.9 6.2 14.2 13.0 191.4 14.6 25.7 48.1 28.4 12.2 242.0 9.0 6.2 0.5 0.2 37.9 8.8 22.6 25.1 130.2 6.1 4.3 12.2 0.4 32.9 28.0 31.6 1.9 5.7 13.2 34.1 0.4 4.8 2.3 6.8 64.4 CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 504.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 999.7;Ductal cells: 992.1;Exocrine glandular cells: 869.6;Langerhans cells: 1934.2;Suprabasal keratinocytes: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 1650.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 1200000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: AB_2076596, HPA005785: AB_1078467" "unprognostic (5.33e-2)" "unprognostic (1.85e-1)" "unprognostic (4.97e-2)" "unprognostic (9.90e-3)" "unprognostic (3.50e-3)" "unprognostic (1.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.12e-2)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-3)" "unprognostic (4.63e-2)" "prognostic unfavorable (1.78e-8)" "unprognostic (6.41e-2)" "unprognostic (4.14e-2)" "unprognostic (3.93e-2)" "unprognostic (7.98e-2)" 143.7 42.4 29.2 218.0 33.9 308.1 164.7 63.0 25.1 146.0 16.8 91.1 53.0 200.4 20.1 227.8 69.0 129.7 30.4 33.0 116.5 31.3 31.0 214.1 108.8 114.9 102.3 11.7 263.2 6.0 8.1 74.1 118.3 87.3 111.5 38.0 504.2 57.0 17.1 433.3 60.8 175.8 114.3 83.8 61.5 6.6 62.8 64.2 76.2 27.7 188.7 235.2 193.4 114.9 493.0 448.6 4.3 1.2 252.6 691.5 1.6 962.2 740.3 521.3 288.2 30.4 150.4 0.7 126.5 1350.2 1065.4 820.1 9.9 1013.9 716.4 110.3 6.2 18.9 198.3 0.3 262.3 254.6 1124.3 315.4 778.3 693.2 552.7 1650.0 184.3 0.1 4.0 157.9 518.9 3.0 25.6 166.9 9.8 8.7 136.4 1.4 89.3 7.5 777.4 138.1 2.0 1.4 185.2 5.5 462.8 38.6 25.7 15.1 547.3 646.6 120.0 815.8 1006.0 281.6 327.7 3.7 980.4 145.1 969.8 127.4 403.0 35.4 140.6 257.8 196.5 122.5 210.1 186.5 229.0 90.0 179.7 153.6 92.6 322.3 356.1 79.9 309.7 437.3 29.2 33.9 63.0 25.1 33.0 116.5 114.9 102.3 118.3 114.3 62.8 114.9 41.0 96.1 361.8 54.5 250.1 999.7 297.7 335.3 228.2 0.6 139.6 71.2 8.6 27.1 125.6 20.2 2.1 4.5 257.0 14.0 1.9 992.1 41.3 43.6 395.4 50.9 100.1 94.4 0.4 869.6 3.6 282.2 39.8 196.9 763.2 25.2 13.2 3.6 226.6 0.0 0.4 93.3 30.5 474.3 1934.2 24.3 22.4 523.9 604.7 8.4 594.2 29.6 62.8 0.5 11.2 813.1 10.9 0.4 216.3 386.7 6.0 1.6 18.8 2.0 157.8 197.2 227.9 0.4 0.4 279.3 1024.9 17.9 430.8 1.0 79.1 330.7 CD48 "BCM1, BLAST, hCD48, mCD48, SLAMF2" ENSG00000117091 "CD48 molecule" P09326 1 160678746-160711831 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 148.4;lymphoid tissue: 283.9" "Cell type enhanced" "Detected in many" "B-cells: 336.1;dendritic cells: 251.2;Kupffer cells: 245.8;Macrophages: 218.3;monocytes: 366.6;NK-cells: 454.2;T-cells: 376.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 220.9;HMC-1: 236.9;U-266/70: 501.4;U-266/84: 360.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002497, HPA055146" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 2000000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoli fibrillar center, Cytosol" "CAB002497: AB_563586, HPA055146: AB_2682716" "prognostic favorable (3.91e-4)" "unprognostic (1.72e-3)" "prognostic favorable (4.17e-4)" "unprognostic (1.58e-3)" "unprognostic (2.36e-1)" "unprognostic (1.71e-3)" "unprognostic (2.09e-2)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (3.21e-1)" "unprognostic (4.69e-2)" "unprognostic (9.38e-2)" "unprognostic (8.51e-2)" 11.8 5.9 1.4 115.3 1.5 148.4 18.8 1.5 4.7 10.2 2.3 24.9 20.5 6.7 5.0 8.4 5.7 26.6 4.3 1.3 1.7 4.4 19.9 31.0 283.9 2.6 1.8 3.1 2.0 1.6 1.6 5.8 2.7 8.1 32.5 0.1 14.0 4.4 2.9 3.5 48.3 12.5 2.1 160.0 32.5 2.9 3.2 138.9 5.2 3.4 256.8 41.8 4.5 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 220.9 0.1 0.0 0.0 0.5 0.1 0.0 0.0 6.0 0.0 2.1 0.0 0.0 0.0 27.1 236.9 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.4 78.6 0.0 0.0 78.9 38.4 0.1 0.0 0.0 4.7 0.1 34.3 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.5 0.1 0.0 0.3 0.2 0.4 501.4 360.3 89.9 0.2 66.7 0.1 218.1 327.1 230.8 242.8 470.2 335.8 206.2 275.2 283.4 329.7 161.2 277.9 301.6 82.1 160.7 487.4 57.0 229.9 603.5 1.4 1.5 1.5 4.7 1.3 1.7 2.6 1.8 2.7 2.1 3.2 4.1 3.7 0.0 9.6 0.7 336.1 5.5 0.8 0.0 1.8 0.0 2.0 1.7 1.1 2.8 1.3 3.7 0.0 0.6 251.2 0.1 1.9 0.2 0.1 0.7 0.5 2.8 1.2 21.5 0.1 0.2 0.8 2.4 6.6 0.6 90.7 0.1 7.1 2.0 86.4 0.0 0.1 0.1 0.0 245.8 106.5 0.5 1.8 218.3 39.2 1.0 366.6 0.0 454.2 0.5 0.0 0.1 0.0 0.4 127.4 0.4 0.0 4.9 2.2 0.0 0.0 1.7 2.1 0.5 0.3 0.7 3.0 0.4 376.2 0.0 1.2 0.5 CD5 "LEU1, T1" ENSG00000110448 "CD5 molecule" P06127 11 61102489-61127852 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 46.5" "Cell type enhanced" "Detected in some" "dendritic cells: 7.5;Langerhans cells: 9.3;Muller glia cells: 16.0;T-cells: 57.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 138.2" "Lineage enriched" "Detected in many" 33 "T-cells: 138.2" "Group enriched" "Detected in some" 66 "JURKAT: 21.0;MOLT-4: 70.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB015392, CAB020308, HPA043416, HPA060839" Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB015392: AB_2075324, CAB020308: , HPA043416: AB_2678472, HPA060839: AB_2684376" "prognostic favorable (4.05e-4)" "prognostic favorable (9.16e-5)" "unprognostic (2.33e-1)" "prognostic favorable (9.00e-5)" "unprognostic (1.02e-2)" "prognostic favorable (7.41e-6)" "unprognostic (2.45e-3)" "unprognostic (1.37e-2)" "prognostic favorable (3.93e-4)" "unprognostic (1.25e-2)" "unprognostic (5.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (8.94e-5)" "unprognostic (4.78e-2)" "unprognostic (1.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.06e-1)" 1.4 0.9 0.4 22.6 0.4 12.2 1.0 0.1 0.5 0.9 0.0 2.8 3.1 0.7 0.4 2.3 0.8 4.9 0.9 0.6 0.4 0.8 1.5 5.7 38.0 0.2 0.0 0.8 0.4 0.2 0.4 0.3 0.5 1.0 2.7 1.8 6.4 0.3 0.6 1.4 7.1 1.2 0.0 14.1 7.9 0.8 0.3 46.5 1.0 0.3 22.2 6.2 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.1 70.5 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.6 45.9 0.4 32.8 1.5 108.7 72.5 3.7 3.4 88.4 69.8 1.8 0.4 3.4 4.1 138.2 61.5 0.4 0.4 0.1 0.5 0.6 0.4 0.2 0.0 0.5 0.0 0.3 0.0 0.4 0.0 1.7 0.0 4.1 0.9 0.0 0.0 0.0 0.2 0.4 0.5 0.3 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 2.7 0.0 0.1 0.2 0.0 1.3 0.3 0.0 0.0 0.9 2.6 0.1 1.3 0.0 1.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 9.3 0.9 0.0 1.8 3.6 0.0 2.1 16.0 1.0 0.0 0.1 0.1 0.3 0.0 6.3 0.0 0.0 0.1 0.0 1.3 0.0 0.1 0.6 0.4 0.7 0.2 0.3 0.0 57.0 0.0 0.2 0.2 CD55 "CR, CROM, DAF, TC" ENSG00000196352 "CD55 molecule (Cromer blood group)" P08174 1 207321532-207386804 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 2227.6;Syncytiotrophoblasts: 847.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 662.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 472.3;HMC-1: 665.7;PC-3: 395.0;U-2197: 405.3" "Low region specificity" "Detected in many" "HPA002190, CAB010454, HPA024386" Enhanced "Secreted to blood" NA No 32300000 360000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "CAB010454: AB_2075970, HPA002190: AB_1078472, HPA024386: AB_1846319" "unprognostic (4.08e-2)" "unprognostic (3.22e-1)" "unprognostic (3.41e-1)" "unprognostic (1.63e-1)" "unprognostic (9.05e-2)" "unprognostic (1.08e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (3.57e-2)" "unprognostic (1.55e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (9.36e-4)" "unprognostic (3.41e-2)" "unprognostic (2.04e-1)" "unprognostic (9.70e-2)" "unprognostic (2.33e-2)" 64.9 161.5 13.8 99.6 23.3 134.0 59.0 15.8 28.3 103.3 19.0 47.7 47.7 58.3 17.3 58.3 28.0 49.4 48.4 15.7 29.4 20.5 28.0 224.1 26.7 21.1 20.0 67.7 24.5 28.9 26.3 92.5 26.2 16.1 42.9 9.2 126.1 18.1 108.9 85.9 50.7 46.6 15.2 43.1 44.0 36.0 20.8 15.8 47.6 59.5 41.3 183.2 41.8 34.4 33.2 43.6 0.1 14.6 54.2 55.1 220.7 62.5 100.1 31.3 33.1 139.5 44.3 60.8 50.3 35.8 123.3 17.4 65.2 12.9 29.1 29.0 26.4 79.9 472.3 23.3 162.3 50.5 665.7 25.9 150.5 40.8 171.8 133.8 169.7 9.6 89.6 29.3 19.4 35.6 5.3 37.8 43.2 78.9 395.0 7.4 42.3 50.7 54.3 30.7 17.7 0.4 321.2 64.3 53.9 95.1 54.4 41.5 80.4 17.6 33.2 405.3 23.8 24.7 31.4 42.7 44.8 19.6 78.9 317.7 181.2 247.6 35.0 174.4 51.8 108.2 46.0 36.4 121.7 115.2 102.6 101.9 662.2 134.5 223.7 64.8 34.6 159.3 13.8 23.3 15.8 28.3 15.7 29.4 21.1 20.0 26.2 15.2 20.8 34.4 95.9 2227.6 405.3 2.3 529.8 705.1 214.1 143.6 59.2 3.1 69.9 53.8 72.7 7.2 542.6 23.9 0.0 217.5 201.7 196.1 3.9 98.6 324.6 345.6 101.9 143.4 17.3 79.8 7.6 180.2 411.7 244.7 387.9 709.3 146.9 88.9 46.8 9.1 70.0 1.7 10.7 155.7 77.3 177.5 449.2 66.3 32.6 377.3 160.1 7.5 122.6 4.8 69.0 6.0 54.3 388.9 241.2 9.1 305.4 334.9 138.4 3.2 259.5 3.3 6.6 56.1 98.0 8.9 13.7 273.4 765.9 847.7 215.4 281.5 145.1 578.6 CD59 "16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20" ENSG00000085063 "CD59 molecule (CD59 blood group)" P13987 11 33703010-33736479 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1445.2;Prostatic glandular cells: 1678.0;Urothelial cells: 1531.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 3747.5;U-2197: 3049.9" "CAB001448, HPA026494" Supported Uncertain "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 58000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus, Vesicles" "CAB001448: AB_563604, HPA026494: AB_1846321" "unprognostic (2.07e-2)" "prognostic unfavorable (3.81e-5)" "unprognostic (7.40e-2)" "unprognostic (1.14e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (3.10e-5)" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (4.47e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.92e-5)" "unprognostic (1.66e-2)" "prognostic favorable (1.39e-10)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (3.09e-1)" 517.4 248.3 284.5 209.6 310.8 198.8 555.9 329.0 365.1 305.5 542.2 255.1 120.7 290.7 971.7 478.9 368.1 475.3 608.3 288.2 359.7 577.4 339.8 553.5 148.8 327.9 340.2 228.5 353.6 706.1 250.3 485.6 340.9 256.8 271.4 130.7 693.6 443.2 529.3 282.8 167.9 380.0 330.5 131.8 422.7 127.7 337.0 167.7 308.1 915.0 288.6 550.5 325.5 315.6 297.2 278.4 77.6 212.0 1697.1 1314.9 46.8 1765.7 1778.5 408.9 451.9 129.7 822.1 23.9 291.5 1802.5 475.5 314.0 141.0 1589.9 561.1 475.5 218.2 31.3 846.7 193.1 483.2 183.4 94.8 631.8 387.2 343.3 1550.6 1104.9 2475.5 109.3 207.9 585.9 2575.4 282.7 79.9 70.3 43.5 541.8 1421.8 30.1 232.1 227.8 1304.4 510.0 54.3 79.5 576.2 243.7 298.2 218.0 187.5 18.1 3747.5 838.6 235.5 3049.9 595.9 273.8 558.8 30.4 734.2 1.3 1556.9 164.9 22.3 209.6 50.9 7.9 64.8 63.9 104.9 56.6 95.4 59.6 68.2 41.4 134.3 92.5 4.8 49.9 298.2 53.5 284.5 310.8 329.0 365.1 288.2 359.7 327.9 340.2 340.9 330.5 337.0 315.6 728.0 272.4 247.2 32.3 39.1 286.0 1103.2 951.4 82.0 51.3 434.9 270.0 315.5 444.7 569.7 242.8 33.3 553.5 29.2 344.6 164.4 1445.2 129.4 94.3 91.6 792.6 166.6 206.0 25.1 618.3 407.2 303.5 109.6 115.6 139.4 88.2 585.0 185.7 486.7 47.1 29.9 112.8 722.2 139.4 374.2 61.6 237.3 88.2 1270.0 54.4 161.7 198.3 26.8 32.6 22.2 1195.7 392.2 204.7 149.7 1678.0 41.7 208.2 1042.5 56.2 276.1 159.1 410.7 130.6 31.2 83.7 284.4 836.6 52.4 139.5 104.9 1531.0 CD5L "API6, Spalpha" ENSG00000073754 "CD5 molecule like" O43866 1 157830911-157898256 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 572.9" "Group enriched" "Detected in some" 36 "Hofbauer cells: 279.0;Kupffer cells: 567.0" "Cancer enriched" "Detected in some" 5 "liver cancer: 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA065686, HPA068384" Enhanced "Secreted to blood" NA NA 4030000000 4300000000 "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA065686: AB_2685532, HPA068384: AB_2685979" "unprognostic (2.96e-1)" "unprognostic (2.90e-1)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "prognostic favorable (8.88e-5)" "unprognostic (1.73e-2)" "unprognostic (4.51e-2)" "unprognostic (1.89e-1)" "unprognostic (1.56e-1)" "unprognostic (5.95e-3)" "unprognostic (2.26e-1)" "unprognostic (1.06e-1)" "unprognostic (3.63e-1)" 1.4 0.0 0.0 1.5 0.0 17.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 104.7 1.6 9.2 0.2 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 572.9 0.5 0.1 0.1 6.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 6.1 6.1 279.0 0.0 0.0 0.0 0.0 567.0 0.0 1.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.3 0.3 0.0 0.0 0.0 CD6 Tp120 ENSG00000013725 "CD6 molecule" P30203 11 60971680-61020377 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.6;lymphoid tissue: 43.1" "Cell type enhanced" "Detected in many" "dendritic cells: 25.7;NK-cells: 49.4;Plasma cells: 18.5;T-cells: 107.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 33 "gdT-cell: 27.7;MAIT T-cell: 24.7;memory CD4 T-cell: 51.4;memory CD8 T-cell: 48.4;naive CD4 T-cell: 34.4;naive CD8 T-cell: 25.2;T-reg: 25.5" "Lineage enriched" "Detected in many" 51 "T-cells: 51.4" "Group enriched" "Detected in some" 12 "JURKAT: 10.2;MOLT-4: 39.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002489, CAB016252" Enhanced "Secreted to blood" NA NA 5270000 160000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB002489: AB_563605, CAB016252: AB_631163" "prognostic favorable (1.95e-4)" "prognostic favorable (1.57e-5)" "unprognostic (4.47e-2)" "prognostic favorable (2.41e-4)" "unprognostic (2.06e-2)" "prognostic favorable (5.10e-6)" "unprognostic (8.45e-3)" "unprognostic (8.21e-3)" "unprognostic (2.87e-3)" "unprognostic (5.32e-3)" "unprognostic (2.07e-1)" "unprognostic (5.35e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "unprognostic (6.19e-2)" "unprognostic (5.96e-2)" 1.4 0.9 1.5 21.9 0.9 11.3 1.2 0.5 1.1 1.3 0.7 3.2 4.0 0.9 0.7 1.8 1.4 3.9 0.5 0.6 1.7 1.0 1.4 6.6 43.1 1.5 2.0 0.9 0.6 0.2 0.4 0.3 1.7 1.1 3.1 0.2 3.2 0.4 0.8 1.3 13.6 0.7 0.9 18.0 6.6 0.7 2.5 39.6 1.4 0.3 29.0 4.8 1.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.2 0.0 0.0 0.0 39.2 0.1 0.2 0.2 0.1 0.1 0.0 0.8 0.0 0.1 0.1 0.2 0.0 0.4 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.7 0.0 24.7 1.0 51.4 48.4 0.3 0.9 34.4 25.2 0.7 0.2 0.0 0.0 25.5 13.8 1.5 0.9 0.5 1.1 0.6 1.7 1.5 2.0 1.7 0.9 2.5 0.9 3.2 0.0 2.5 0.3 10.8 2.0 0.2 0.1 0.0 1.4 0.9 0.8 2.6 1.5 0.1 0.0 0.0 0.2 25.7 0.2 0.0 0.2 0.9 0.4 0.3 1.2 0.0 0.0 0.8 0.6 0.2 1.5 8.2 0.3 0.0 0.1 2.5 0.8 2.0 1.7 0.9 0.0 0.0 1.9 4.4 0.4 0.3 3.4 3.6 1.0 2.4 0.0 49.4 0.0 0.2 0.7 0.2 0.0 18.5 0.0 0.1 0.2 0.1 0.2 0.0 1.0 0.9 0.4 0.9 1.0 1.4 0.3 107.3 0.7 0.5 0.4 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 CD7 "GP40, LEU-9, Tp40, TP41" ENSG00000173762 "CD7 molecule" P09564 17 82314868-82317608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.6;lymphoid tissue: 53.7" "Group enriched" "Detected in many" 9 "dendritic cells: 625.0;NK-cells: 1299.7;T-cells: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 231.5" "Group enriched" "Detected in many" 22 "NK-cells: 231.5;T-cells: 71.5" "Cell line enhanced" "Detected in some" "Hep G2: 52.0;JURKAT: 26.7;MOLT-4: 119.2" "Region enhanced" "Detected in some" "cerebral cortex: 3.2" "Not detected" "Not detected" "CAB002594, HPA039079" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002594: , HPA039079: AB_2676337" "unprognostic (3.14e-3)" "prognostic favorable (5.51e-4)" "unprognostic (1.89e-2)" "prognostic favorable (2.03e-5)" "unprognostic (7.69e-3)" "unprognostic (1.09e-3)" "unprognostic (3.28e-2)" "unprognostic (1.34e-1)" "prognostic favorable (2.69e-4)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-1)" "prognostic unfavorable (7.75e-11)" "unprognostic (4.69e-2)" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (1.55e-3)" 8.2 1.3 0.7 32.9 0.8 28.6 2.6 0.8 1.3 2.5 0.9 7.3 12.4 3.0 0.4 3.9 3.9 3.2 1.8 0.6 1.1 7.1 7.7 17.1 36.8 1.4 0.8 0.8 1.2 0.1 1.4 3.3 1.0 4.4 1.9 0.0 3.1 1.0 0.8 1.7 21.1 1.1 1.2 53.7 8.1 0.6 1.1 48.8 3.5 0.1 14.8 3.9 3.9 1.2 0.0 0.0 0.0 0.0 0.1 0.4 12.9 0.0 0.2 0.1 0.2 0.6 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.7 52.0 0.6 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 26.7 0.1 0.0 0.1 0.0 119.2 0.0 0.0 0.0 0.2 0.1 0.1 2.3 0.2 0.0 0.4 0.3 1.8 1.1 0.0 0.3 0.0 0.0 0.0 0.3 0.3 1.0 0.0 1.2 0.2 0.0 0.2 0.0 0.0 0.5 0.4 0.5 66.6 0.2 57.6 0.4 29.8 49.0 0.3 0.2 69.4 71.5 2.3 231.5 0.6 6.9 28.7 30.9 0.7 0.8 0.8 1.3 0.6 1.1 1.4 0.8 1.0 1.2 1.1 1.2 5.3 0.0 0.0 0.0 12.1 7.5 0.6 0.1 1.8 0.0 4.2 3.7 0.5 4.3 0.3 0.0 0.0 0.7 625.0 9.4 0.0 1.3 0.1 2.8 2.0 4.5 0.0 47.7 0.0 0.5 10.3 12.4 43.8 5.3 8.2 0.0 16.8 3.3 3.6 1.7 0.0 1.5 0.0 18.5 8.8 0.0 0.0 19.2 12.4 0.0 11.6 0.0 1299.7 0.0 0.0 0.1 5.8 0.0 82.7 3.8 8.1 1.4 0.5 0.0 0.0 0.5 3.9 0.0 1.3 1.0 4.4 1.9 527.4 0.0 2.1 3.8 CD70 "CD27L, CD27LG, TNFSF7" ENSG00000125726 "CD70 molecule" P32970 19 6583183-6604103 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.4" "Cell type enriched" "Detected in some" 4 "monocytes: 239.4" "Cancer enriched" "Detected in many" 4 "renal cancer: 24.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 44.2" "Group enriched" "Detected in many" 35 "B-cells: 24.2;T-cells: 44.2" "Cell line enhanced" "Detected in many" "SiHa: 189.2;THP-1: 157.3;U-251 MG: 234.2;U-266/70: 399.5;U-266/84: 312.7;U-698: 138.1" "Region enriched" "Detected in single" 25 "cerebellum: 11.3" "Low region specificity" "Detected in all" HPA046582 Uncertain Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "HPA046582: " "unprognostic (8.71e-2)" "unprognostic (9.91e-2)" "unprognostic (1.61e-1)" "unprognostic (2.33e-4)" "unprognostic (1.73e-2)" "unprognostic (1.51e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.92e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (2.57e-2)" "unprognostic (1.40e-1)" "unprognostic (2.27e-1)" "unprognostic (2.08e-1)" 2.4 0.1 0.1 3.2 0.1 0.8 1.1 0.5 0.3 0.4 0.3 2.2 0.5 0.1 0.0 0.7 0.2 0.4 0.1 0.1 0.2 0.5 0.2 0.8 3.4 0.2 0.2 0.1 0.3 0.0 0.1 0.1 0.2 0.2 1.5 0.0 0.2 0.0 0.3 1.4 2.2 0.1 0.0 2.9 1.0 0.3 0.1 1.5 0.3 0.9 1.9 1.1 0.5 0.4 1.3 39.1 0.1 75.6 1.7 1.0 0.1 0.0 0.3 0.3 2.6 0.1 0.5 74.2 4.1 0.4 81.8 53.2 46.5 3.6 0.0 0.2 1.6 0.0 56.8 0.1 0.0 0.0 2.2 0.5 0.4 43.9 31.1 12.2 0.3 0.1 1.3 2.5 1.1 0.2 1.3 94.3 0.9 0.0 70.0 20.3 0.1 16.3 24.6 0.2 0.0 0.0 189.2 0.0 0.8 0.2 0.5 157.3 1.0 0.6 32.6 0.0 234.2 399.5 312.7 138.1 41.0 23.8 14.8 0.8 0.1 0.1 3.3 0.0 8.1 24.2 5.3 8.8 0.1 9.9 0.7 2.1 0.2 0.9 0.0 0.3 44.2 1.6 0.1 0.1 0.5 0.3 0.1 0.2 0.2 0.2 0.2 0.0 0.1 0.4 0.6 0.0 0.0 0.0 50.9 5.7 0.1 11.1 0.0 0.0 0.1 0.3 0.2 0.0 0.3 1.8 0.0 0.0 2.3 0.0 0.0 0.3 0.0 0.4 0.0 1.6 1.8 0.0 0.1 0.7 0.0 11.3 0.5 0.2 1.3 0.1 0.7 0.3 0.4 0.0 0.7 0.0 18.3 0.6 14.6 0.0 0.0 3.0 3.6 0.0 239.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 24.9 0.2 0.0 0.2 0.7 0.0 0.0 0.4 0.9 0.2 0.6 0.4 5.4 0.0 14.1 0.0 0.4 0.0 CD79A "IGA, MB-1" ENSG00000105369 "CD79a molecule" P11912 19 41877279-41881372 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 152.3;lymphoid tissue: 545.2" "Group enriched" "Detected in some" 5 "B-cells: 1186.4;Plasma cells: 956.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 38 "memory B-cell: 1273.8;naive B-cell: 1457.5" "Lineage enriched" "Detected in all" 40 "B-cells: 1457.5" "Group enriched" "Detected in some" 22 "Daudi: 1598.7;REH: 491.0;U-698: 1366.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000019, HPA056444" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB000019: AB_2244527, HPA056444: " "prognostic favorable (8.45e-5)" "unprognostic (1.63e-3)" "unprognostic (4.13e-3)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "prognostic favorable (1.18e-5)" "unprognostic (1.23e-2)" "unprognostic (8.11e-3)" "unprognostic (9.41e-3)" "unprognostic (1.12e-2)" "unprognostic (2.53e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (6.08e-2)" "unprognostic (3.39e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-1)" 4.8 4.9 0.2 213.4 0.2 47.2 9.5 0.2 0.4 3.6 0.1 47.3 37.9 2.4 1.4 9.9 1.8 13.0 2.9 0.1 0.1 3.4 2.6 8.9 482.4 0.3 0.2 3.7 0.6 0.1 0.3 1.2 0.2 4.3 28.9 0.0 28.5 2.2 0.7 0.4 152.3 2.2 0.6 286.5 76.9 2.4 0.2 93.7 8.1 0.4 545.2 32.3 1.9 0.3 1.1 0.8 0.3 0.1 0.2 0.7 0.2 0.2 0.0 0.3 0.0 0.0 0.1 1598.7 1.2 0.0 0.1 0.0 0.2 0.2 0.0 0.5 0.7 2.7 0.0 1.7 0.2 2.6 1.8 0.5 0.6 0.2 0.0 0.0 0.0 8.0 3.1 0.4 0.1 1.1 1.6 9.9 0.1 0.1 0.4 491.0 0.8 2.5 0.1 0.0 0.5 0.5 0.8 0.5 1.3 0.0 0.0 4.8 1.6 0.1 4.3 0.3 0.8 7.8 1.4 1366.7 0.0 52.1 0.1 12.4 1.5 6.9 1.7 1.8 0.7 1273.8 4.1 2.1 2.5 1457.5 4.9 26.3 4.6 2.6 4.3 36.3 10.4 62.7 0.2 0.2 0.2 0.4 0.1 0.1 0.3 0.2 0.2 0.6 0.2 0.3 0.2 0.0 2.4 0.0 1186.4 1.8 0.5 0.5 0.6 0.0 0.7 0.9 0.2 1.5 0.2 0.0 0.0 0.2 18.2 0.7 0.0 1.8 0.2 0.1 0.3 0.5 0.0 10.5 0.0 25.6 0.4 2.2 6.6 0.2 0.0 0.4 2.2 1.0 0.8 0.0 0.0 0.4 0.0 4.1 1.4 0.0 0.3 5.3 138.7 0.0 6.3 0.0 15.5 0.0 0.0 181.7 0.4 0.4 956.7 0.3 0.2 0.9 0.0 0.0 0.0 0.2 0.7 0.3 0.6 0.9 1.4 0.1 23.5 0.2 5.3 0.2 CD80 "B7-1, B7.1, CD28LG, CD28LG1" ENSG00000121594 "CD80 molecule" P33681 3 119524293-119559614 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 3.0;lymphoid tissue: 6.8" "Group enriched" "Detected in some" 4 "Langerhans cells: 17.4;monocytes: 65.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;T-reg: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 11.9;HDLM-2: 42.3;Karpas-707: 17.0;U-266/70: 7.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB025368, HPA050092" Enhanced "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB025368: , HPA050092: AB_2681012" "unprognostic (2.36e-1)" "unprognostic (1.55e-2)" "unprognostic (5.91e-2)" "unprognostic (1.24e-1)" "unprognostic (3.14e-1)" "unprognostic (1.18e-1)" "unprognostic (1.86e-2)" "unprognostic (4.14e-3)" "unprognostic (1.02e-2)" "unprognostic (4.96e-3)" "unprognostic (1.16e-2)" "unprognostic (1.15e-1)" "unprognostic (9.03e-8)" "unprognostic (3.20e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (1.94e-2)" 0.4 0.1 0.1 5.3 0.1 1.4 0.2 0.2 0.3 0.2 0.7 0.7 1.0 0.2 0.0 0.1 0.1 0.6 0.1 0.2 0.1 0.1 1.5 3.0 5.6 0.4 0.1 0.0 0.2 1.7 0.1 0.4 0.3 0.1 1.3 0.0 0.2 0.2 0.1 0.0 0.8 0.3 0.4 3.4 0.6 0.2 0.5 2.5 0.6 0.0 6.8 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 17.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.2 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.4 0.1 0.3 0.4 0.5 0.4 0.2 0.0 1.5 0.0 7.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.4 0.0 1.3 0.0 0.4 0.0 0.0 4.5 17.4 0.5 0.0 8.5 0.0 1.0 65.2 0.0 0.0 0.5 0.2 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 121.3;Kupffer cells: 107.8;Langerhans cells: 148.3;Macrophages: 151.8;Microglial cells: 78.7;monocytes: 489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cell line enriched" "Detected in some" 7 "HDLM-2: 296.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" 7.8 5.3 3.5 34.5 3.4 10.3 4.4 4.0 3.6 3.5 4.8 6.3 3.7 2.4 1.0 4.0 2.1 14.3 2.7 3.2 6.1 1.9 11.2 18.6 28.8 7.2 5.5 2.1 2.6 2.9 1.1 15.0 7.0 2.4 7.7 0.9 2.3 2.5 0.8 2.0 6.8 7.4 5.3 23.4 5.2 3.1 5.0 10.6 1.3 0.8 22.0 14.9 1.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 296.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.2 0.0 32.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.4 0.0 0.1 0.0 0.1 15.1 0.6 35.1 0.0 0.9 0.0 0.1 79.9 0.8 0.0 79.0 0.0 41.0 0.2 0.3 78.8 28.5 0.2 0.1 0.9 3.7 85.2 8.3 1.6 33.4 3.5 3.4 4.0 3.6 3.2 6.1 7.2 5.5 7.0 5.3 5.0 10.2 0.9 0.0 7.7 0.3 36.5 3.6 0.1 1.3 0.0 0.0 0.4 1.3 0.3 1.5 3.2 1.8 0.0 1.8 3.3 0.0 0.0 0.2 3.7 0.1 0.0 2.6 0.0 1.3 0.2 3.5 0.8 0.8 0.5 0.0 2.5 0.1 1.8 0.8 121.3 0.0 0.3 0.0 0.0 107.8 148.3 2.7 0.0 151.8 7.2 78.7 489.4 0.0 0.0 0.5 0.1 0.3 0.0 0.0 20.6 0.3 0.0 0.1 0.1 0.4 0.0 0.3 0.7 0.2 0.3 0.2 4.0 1.9 2.1 0.1 0.0 0.3 CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 369.0" "Group enriched" "Detected in many" 4 "dendritic cells: 111.7;T-cells: 242.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 234.4;memory CD8 T-cell: 523.0;naive CD8 T-cell: 476.8" "Lineage enriched" "Detected in many" 19 "T-cells: 523.0" "Cell line enhanced" "Detected in some" "JURKAT: 4.0;MOLT-4: 15.2;RPMI-8226: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 490000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" 5.3 4.6 2.1 21.2 2.8 22.5 4.7 1.9 3.0 3.8 1.4 4.9 11.8 3.0 3.6 4.4 4.0 9.8 2.3 2.1 2.1 1.8 7.4 10.5 45.0 2.8 2.1 2.5 2.6 1.1 1.5 0.6 2.5 3.4 5.9 0.2 8.3 1.9 0.8 1.3 20.7 2.4 2.2 117.1 16.4 1.0 2.3 369.0 4.4 0.4 21.4 9.1 4.0 2.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.6 15.2 0.9 0.5 0.1 0.2 0.1 0.7 3.3 0.0 0.3 0.7 1.9 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 30.0 0.3 234.4 0.6 2.3 523.0 0.4 0.6 2.2 476.8 4.3 27.9 0.9 1.2 0.8 152.4 2.1 2.8 1.9 3.0 2.1 2.1 2.8 2.1 2.5 2.2 2.3 2.1 2.2 0.0 4.6 0.0 5.7 2.0 0.2 0.0 0.0 0.3 1.5 1.5 3.4 1.5 0.6 0.0 0.0 0.0 111.7 0.2 0.0 0.2 0.3 0.5 0.3 1.3 0.0 7.8 4.2 0.0 0.0 2.6 8.2 0.4 2.5 0.0 6.4 2.3 0.1 0.0 3.1 0.3 0.0 1.9 11.5 0.2 0.0 6.6 0.0 1.0 5.9 0.1 38.1 0.0 0.2 0.0 0.0 0.0 30.8 0.2 0.0 0.4 1.5 0.4 0.0 1.1 1.4 0.4 0.4 1.1 1.8 0.1 242.4 0.0 0.6 0.1 CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 459.6" "Group enriched" "Detected in many" 8 "dendritic cells: 53.2;T-cells: 162.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 601.8;naive CD8 T-cell: 1053.9" "Lineage enriched" "Detected in all" 25 "T-cells: 1053.9" "Cell line enriched" "Detected in some" 60 "RPMI-8226: 1113.4" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" 1.9 1.9 0.4 10.6 0.3 8.3 2.9 1.1 0.6 33.4 0.1 2.1 5.0 1.2 1.1 1.6 1.5 4.3 1.0 0.1 1.2 1.0 1.6 4.2 25.9 5.0 2.1 0.9 0.9 4.6 8.8 0.3 4.8 1.7 3.0 0.0 2.4 1.0 0.6 1.4 15.1 1.1 0.7 15.6 5.1 0.4 2.4 459.6 2.0 0.4 15.1 3.4 1.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.1 0.2 0.0 1113.4 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 42.0 1.0 0.8 15.7 1.1 79.3 0.7 1.9 601.8 0.6 1.2 4.6 1053.9 6.1 1.1 1.7 1.0 2.2 427.6 0.4 0.3 1.1 0.6 0.1 1.2 5.0 2.1 4.8 0.7 2.4 0.5 1.3 6.4 5.5 0.0 4.4 4.0 2.2 0.0 0.6 0.0 2.2 2.8 1.0 1.5 0.0 0.0 0.0 0.1 53.2 0.1 0.0 0.1 0.5 0.2 0.5 0.7 0.0 1.7 0.4 0.0 0.0 2.0 7.1 0.2 0.0 0.0 0.7 0.5 0.1 0.0 0.5 4.6 0.0 4.0 4.3 0.5 0.0 4.1 5.4 5.6 7.5 0.0 10.3 0.0 0.1 0.0 0.1 0.0 10.8 0.7 12.4 0.2 0.0 0.0 0.0 2.0 1.2 0.2 0.1 0.5 2.8 0.0 162.9 0.0 7.5 0.3 CD99 MIC2 ENSG00000002586 "CD99 molecule (Xg blood group)" P14209 X 2691187-2741309 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1614.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000020, HPA035304" Supported Approved "Golgi apparatus" NA NA 62000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "CAB000020: AB_2076419, HPA035304: AB_10672861" "unprognostic (3.71e-3)" "unprognostic (2.90e-1)" "unprognostic (5.97e-3)" "unprognostic (7.01e-3)" "unprognostic (2.14e-2)" "unprognostic (6.98e-3)" "unprognostic (3.89e-3)" "unprognostic (1.54e-2)" "unprognostic (1.06e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-2)" "unprognostic (1.87e-1)" "prognostic unfavorable (5.87e-7)" "unprognostic (2.11e-2)" "unprognostic (2.18e-1)" "unprognostic (5.37e-2)" "unprognostic (3.61e-2)" 476.3 143.3 132.0 119.2 142.1 105.4 327.7 148.8 135.4 367.4 126.5 353.2 148.5 305.5 132.4 208.8 249.4 264.5 343.7 128.8 247.5 112.7 227.7 256.5 146.6 210.9 178.1 303.0 234.6 46.8 132.9 194.8 216.8 270.3 152.9 15.1 184.2 258.4 163.7 284.7 210.0 226.1 224.4 186.0 209.1 199.6 139.4 562.1 152.6 168.3 129.2 296.3 314.6 227.6 259.4 276.5 308.5 424.8 1217.7 939.2 195.0 681.6 1050.1 419.2 604.8 412.3 179.1 18.3 130.0 929.4 217.5 99.4 124.1 168.4 337.5 350.8 321.2 53.1 179.5 353.4 390.1 81.7 375.0 580.1 204.9 223.7 155.6 271.8 766.4 256.3 66.4 0.9 391.9 191.2 672.3 266.8 107.5 28.6 310.0 118.7 273.2 513.5 240.7 165.4 1.0 141.2 168.7 138.2 432.6 744.9 129.6 229.4 750.2 509.7 86.1 487.1 230.2 1.0 0.8 116.1 338.1 203.1 323.8 23.6 526.0 18.3 1089.2 131.2 620.5 340.1 730.3 961.1 496.5 231.8 267.4 549.7 45.1 377.3 32.3 682.1 833.7 1421.2 132.0 142.1 148.8 135.4 128.8 247.5 210.9 178.1 216.8 224.4 139.4 227.6 297.7 64.1 68.3 20.5 172.0 250.6 207.4 274.4 138.9 5.1 66.9 48.3 86.6 112.9 88.4 71.7 0.0 223.6 507.7 68.4 13.7 145.3 8.8 180.2 279.7 387.7 80.8 136.5 0.9 138.4 189.7 604.7 116.7 188.8 230.4 1614.3 512.9 123.0 799.8 0.0 1.1 150.8 54.9 187.4 579.9 26.4 645.2 342.4 691.9 37.5 175.9 52.0 632.4 1.0 0.9 139.9 158.2 511.2 300.2 385.8 230.9 63.3 117.5 3.2 341.8 231.1 351.9 16.4 56.9 147.9 222.9 123.0 468.9 403.2 262.3 307.0 CDADC1 NYD-SP15 ENSG00000102543 "Cytidine and dCMP deaminase domain containing 1" Q9BWV3 13 49247925-49293485 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 174.6;Late spermatids: 77.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 9.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047615, HPA058314" Uncertain Approved Nucleoplasm No No "Cluster 18: Basophils - Vesicular transport" "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA047615: AB_2680104, HPA058314: AB_2683677" "unprognostic (2.81e-1)" "unprognostic (2.64e-1)" "unprognostic (2.20e-1)" "unprognostic (2.86e-1)" "unprognostic (2.75e-1)" "unprognostic (1.11e-2)" "unprognostic (1.58e-3)" "prognostic favorable (6.03e-4)" "unprognostic (7.68e-2)" "unprognostic (6.06e-2)" "unprognostic (2.35e-3)" "unprognostic (1.89e-1)" "prognostic favorable (1.19e-5)" "unprognostic (3.35e-2)" "unprognostic (5.92e-3)" "unprognostic (5.40e-2)" "unprognostic (8.27e-3)" 5.0 6.8 4.9 2.3 4.5 6.3 4.2 5.8 6.5 4.0 5.8 4.7 3.1 3.8 5.1 3.2 4.2 2.7 4.3 4.5 5.5 9.5 8.1 3.5 3.1 4.9 5.4 4.5 2.7 5.5 3.2 2.0 5.1 3.9 3.2 5.2 3.4 4.4 4.4 2.2 3.0 3.7 4.7 4.1 3.9 7.9 5.6 4.3 9.4 5.2 2.6 3.5 3.6 5.4 2.1 2.6 2.2 2.7 10.8 5.9 1.1 5.0 3.1 2.5 2.6 2.6 1.7 2.9 1.0 2.2 2.4 3.6 4.6 2.2 3.2 6.3 3.7 3.3 2.5 2.7 4.7 6.3 1.7 4.1 5.5 2.3 3.0 4.4 3.7 5.6 2.1 2.1 3.2 0.7 6.0 5.1 0.8 3.6 2.2 4.0 2.4 2.9 3.6 0.7 1.3 1.1 3.4 2.1 2.9 1.4 1.5 5.4 2.8 1.3 2.4 3.5 2.4 0.6 2.4 1.8 1.1 7.2 3.7 9.9 1.1 0.9 1.4 0.9 1.5 0.4 1.0 1.9 0.8 0.6 0.9 1.3 1.2 1.2 1.8 0.8 1.6 0.9 4.9 4.5 5.8 6.5 4.5 5.5 4.9 5.4 5.1 4.7 5.6 5.4 12.4 6.4 12.4 9.4 6.6 8.0 7.3 10.7 11.4 12.7 8.5 9.7 15.0 5.7 8.6 18.4 12.5 4.6 19.1 4.7 9.8 5.3 174.6 12.6 14.6 8.7 6.7 10.3 16.0 10.7 10.9 17.1 6.6 6.0 24.7 10.0 11.7 11.5 6.2 3.3 21.4 6.9 4.1 9.1 8.3 77.7 15.8 9.9 7.2 3.7 5.4 25.9 9.2 14.1 12.4 6.7 5.7 14.3 10.6 7.3 7.9 25.4 18.9 12.2 0.0 15.3 17.8 39.3 15.5 7.7 5.4 2.5 14.1 17.2 6.0 5.7 CDC23 "ANAPC8, APC8, CUT23" ENSG00000094880 "Cell division cycle 23" Q9UJX2 5 138187650-138213343 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039593 Approved "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA039593: AB_10795146" "unprognostic (5.45e-2)" "unprognostic (1.83e-1)" "unprognostic (5.26e-3)" "unprognostic (3.46e-2)" "unprognostic (8.46e-2)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.37e-1)" "unprognostic (2.85e-1)" "unprognostic (3.12e-1)" "unprognostic (3.64e-1)" "unprognostic (1.64e-1)" "unprognostic (9.68e-3)" "unprognostic (9.30e-2)" "unprognostic (1.02e-1)" "unprognostic (3.12e-2)" "unprognostic (3.46e-1)" 12.4 11.8 12.3 13.6 12.7 14.1 17.4 14.5 15.7 12.7 10.0 14.0 11.4 15.1 17.2 14.5 12.4 10.6 15.3 12.5 11.7 19.8 18.3 13.3 17.9 11.6 11.6 14.8 9.5 18.4 10.0 26.2 11.8 15.5 15.6 14.0 11.8 13.6 10.1 16.5 10.9 16.9 12.0 14.4 12.8 15.1 11.8 20.3 16.1 12.2 19.4 14.6 11.7 13.1 42.7 35.8 51.2 62.7 22.2 24.8 59.8 34.8 26.8 70.0 72.3 83.9 46.7 52.0 52.3 32.6 71.9 41.6 67.5 54.0 64.4 40.3 61.9 41.5 30.6 37.7 30.8 33.1 39.4 26.0 36.4 43.9 37.0 29.1 47.3 55.1 43.7 39.1 34.9 28.6 65.6 40.3 32.6 52.6 28.6 58.3 60.8 36.0 38.8 26.9 40.7 36.8 51.8 33.1 61.1 97.3 49.3 41.2 32.6 42.0 27.6 37.1 56.7 43.6 46.7 67.7 28.9 57.2 37.2 41.4 15.1 21.6 18.3 16.5 22.2 16.8 17.9 19.3 14.4 16.2 23.4 20.7 2.9 27.0 12.3 10.4 18.1 16.0 12.3 12.7 14.5 15.7 12.5 11.7 11.6 11.6 11.8 12.0 11.8 13.1 11.7 19.2 9.5 9.8 9.7 8.0 13.9 18.8 11.4 10.5 11.8 10.5 19.0 5.7 23.3 9.2 25.0 31.9 10.3 8.2 39.2 12.5 0.8 9.1 15.1 13.2 6.1 19.8 14.0 7.2 20.4 11.9 8.6 12.3 9.5 13.5 11.0 20.0 15.7 16.8 12.8 9.0 26.4 13.0 4.7 1.1 8.7 8.8 12.4 5.6 12.6 16.4 9.2 10.6 13.5 9.7 4.6 6.4 11.4 11.3 5.6 26.4 10.4 13.1 6.6 9.7 13.2 14.5 25.3 15.9 10.1 40.8 11.2 13.1 9.8 13.8 CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188417 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.3;lymphoid tissue: 8.8;testis: 13.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 111.2;Early spermatids: 18.3;Late spermatids: 31.8;Spermatogonia: 16.3" "Cancer enhanced" "Detected in many" "testis cancer: 19.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005855, HPA008803" Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Golgi apparatus" "HPA005855: AB_1846364, HPA008803: " "unprognostic (1.49e-1)" "unprognostic (8.13e-2)" "unprognostic (1.20e-2)" "unprognostic (1.43e-3)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (7.05e-7)" "unprognostic (1.35e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-3)" "unprognostic (4.41e-2)" "unprognostic (9.09e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-3)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" 0.7 0.9 0.8 3.3 0.8 15.3 1.1 0.7 1.0 0.6 0.7 3.5 2.0 0.6 0.9 2.4 0.2 0.3 0.4 0.8 2.0 0.7 0.8 0.3 4.4 1.1 1.9 2.2 0.7 0.8 0.8 2.6 1.7 0.6 3.9 2.0 0.8 0.6 0.4 0.6 1.8 1.1 0.8 2.0 0.9 13.3 2.0 8.8 1.8 0.3 5.6 0.9 0.9 0.7 22.2 10.7 50.0 27.2 1.7 3.2 34.2 29.9 11.3 36.7 29.6 46.8 11.2 64.9 11.4 8.0 23.4 16.3 86.6 20.6 38.6 21.4 45.1 83.8 19.0 23.1 1.7 59.4 23.4 1.7 3.1 45.8 19.6 4.6 14.1 47.8 67.6 33.6 20.1 11.8 74.8 46.6 73.4 20.2 24.2 33.2 32.9 35.1 9.5 20.7 23.5 28.8 18.6 21.6 9.5 31.7 11.3 41.9 7.2 18.0 27.7 20.3 41.4 16.7 54.2 101.5 13.5 65.2 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.0 0.8 2.0 1.1 1.9 1.7 0.8 2.0 0.7 0.3 0.0 0.0 1.0 1.1 0.4 0.4 0.8 1.8 0.5 1.2 1.0 111.2 0.0 0.1 0.0 2.1 4.2 0.2 2.4 0.0 0.4 18.3 0.5 0.9 2.7 1.2 8.0 0.2 0.9 7.4 1.5 1.5 1.3 0.0 4.6 1.4 0.3 3.1 0.0 0.5 2.0 0.0 0.6 0.9 31.8 1.5 0.5 0.0 0.0 0.1 1.1 0.0 0.5 0.0 1.1 0.8 1.9 13.0 0.7 0.4 0.4 0.2 0.4 0.0 0.1 2.2 14.5 16.3 4.3 0.0 0.3 0.6 2.4 4.1 0.5 CDC40 "EHB3, FLJ10564, PRP17, PRPF17" ENSG00000168438 "Cell division cycle 40" O60508 6 110180141-110254275 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046620 Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA046620: AB_2679722" "unprognostic (4.19e-3)" "unprognostic (2.41e-2)" "unprognostic (1.23e-2)" "unprognostic (1.10e-2)" "unprognostic (4.25e-2)" "unprognostic (3.64e-2)" "unprognostic (3.42e-2)" "unprognostic (5.24e-1)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (9.27e-2)" "unprognostic (1.92e-1)" "unprognostic (4.68e-2)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (3.01e-1)" "unprognostic (2.09e-1)" 11.1 14.7 6.9 13.3 10.3 38.2 13.6 6.5 10.9 11.3 7.3 11.1 11.1 11.7 10.4 10.7 11.0 10.4 10.5 10.2 6.1 16.3 16.9 11.0 19.6 4.7 5.0 16.1 12.4 14.0 9.4 9.9 5.0 12.5 12.1 14.8 11.0 9.4 11.6 10.6 11.0 10.1 5.2 16.0 11.4 11.8 5.2 18.6 15.9 11.6 18.6 12.6 8.5 9.2 11.3 10.4 18.2 31.8 18.3 18.8 14.8 21.5 26.4 21.3 26.9 22.8 11.3 37.8 23.7 19.2 22.7 15.8 28.2 17.5 30.1 30.5 21.3 31.0 14.4 12.4 24.2 40.2 39.8 17.1 16.4 22.5 18.1 15.9 21.6 24.3 31.5 22.0 21.3 11.0 29.9 14.9 18.1 15.1 11.2 26.0 21.4 13.1 15.5 23.6 19.4 19.1 15.8 13.8 15.9 16.6 12.8 38.1 24.5 11.5 11.4 27.3 24.1 11.0 15.9 33.8 18.6 33.2 17.4 28.6 18.7 20.4 13.8 20.3 13.7 29.5 13.7 14.3 15.9 28.3 16.2 14.1 20.8 16.5 23.4 24.9 16.8 10.2 6.9 10.3 6.5 10.9 10.2 6.1 4.7 5.0 5.0 5.2 5.2 9.2 38.9 32.1 37.6 18.3 85.7 26.4 26.2 43.1 36.5 94.4 32.2 32.8 21.5 30.0 37.5 27.6 43.8 32.9 79.2 20.9 56.7 35.8 257.8 34.6 48.4 35.5 26.4 44.2 65.4 37.3 30.9 35.8 35.2 30.4 49.4 43.0 38.9 56.6 37.8 94.2 25.6 29.8 22.4 44.9 28.6 84.6 67.4 49.6 10.6 24.4 76.0 46.1 57.7 27.2 43.6 28.5 28.9 45.1 27.8 23.4 29.1 74.0 31.0 84.0 78.9 38.2 39.3 20.9 22.5 37.6 27.1 28.7 59.0 70.6 35.5 22.4 CDCA7L "JPO2, R1, RAM2" ENSG00000164649 "Cell division cycle associated 7 like" Q96GN5 7 21900899-21945903 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 51.0;Spermatogonia: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 101.0;naive B-cell: 124.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "olfactory bulb: 10.1" "HPA027169, HPA074623" Approved Supported Nucleoplasm,Nucleoli,Cytosol No Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA027169: AB_1856058, HPA074623: " "unprognostic (5.13e-3)" "unprognostic (5.94e-2)" "unprognostic (1.91e-1)" "unprognostic (4.63e-2)" "unprognostic (2.33e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.36e-6)" "unprognostic (4.09e-2)" "unprognostic (2.86e-1)" "unprognostic (3.87e-2)" "unprognostic (3.22e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (2.00e-1)" "unprognostic (1.60e-1)" "unprognostic (1.73e-1)" "unprognostic (2.83e-3)" 5.9 1.4 3.9 15.0 9.1 51.7 15.7 5.7 5.2 8.7 17.8 17.0 10.7 13.8 5.5 11.2 11.5 8.1 25.3 3.9 3.5 2.8 4.8 14.0 37.1 6.9 4.8 21.8 13.0 1.8 1.1 4.7 3.8 7.3 19.0 5.1 9.0 7.6 6.2 18.5 13.6 11.9 5.0 13.3 17.8 18.5 7.8 49.0 29.8 3.4 31.8 6.3 8.1 9.8 84.5 27.6 26.0 0.6 14.5 17.9 0.0 65.9 58.2 51.8 73.5 11.3 75.4 173.6 21.8 59.3 102.4 51.1 41.4 69.4 103.6 0.3 28.6 42.3 83.8 7.4 21.1 111.1 0.4 35.2 12.7 40.0 116.9 54.9 104.8 133.5 58.3 0.1 41.4 34.5 146.1 46.1 153.2 17.4 36.2 141.0 94.0 119.8 15.4 14.8 96.9 79.7 30.3 19.9 29.9 34.4 45.6 54.6 43.0 57.1 68.5 101.3 83.8 90.6 63.6 223.0 55.7 154.6 54.5 1.1 2.3 43.2 2.2 3.8 0.3 101.0 6.4 3.2 14.9 124.5 30.9 12.8 3.8 3.4 4.9 75.9 9.9 12.2 3.9 9.1 5.7 5.2 3.9 3.5 6.9 4.8 3.8 5.0 7.8 9.8 1.0 19.2 31.5 7.5 51.0 27.1 23.7 6.9 17.1 1.5 12.5 20.7 38.7 11.5 19.0 0.0 2.1 0.5 30.7 8.4 3.9 8.9 7.3 5.4 2.7 4.8 10.7 21.9 0.5 6.2 0.3 13.4 18.3 5.3 8.8 14.9 1.4 4.0 10.8 13.5 1.0 26.1 8.2 15.2 3.5 5.2 4.1 7.0 8.8 1.9 1.6 2.4 1.0 15.1 8.7 3.9 7.4 2.6 20.2 14.2 1.5 0.1 4.2 2.7 13.1 6.8 12.4 4.6 63.5 9.6 7.7 0.3 5.4 8.3 23.0 6.2 CDCP1 "CD318, SIMA135" ENSG00000163814 "CUB domain containing protein 1" Q9H5V8 3 45082277-45146422 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.2;Basal respiratory cells: 92.6;Pancreatic endocrine cells: 137.1;Urothelial cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.3;NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 94.9;HBEC3-KT: 109.0;hTEC/SVTERT24-B: 265.2;hTERT-HME1: 177.9;PC-3: 89.7;RPTEC TERT1: 81.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010978, HPA010979, CAB025637" Enhanced "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025637: , HPA010978: AB_1846403, HPA010979: AB_1846401" "unprognostic (9.31e-2)" "unprognostic (4.50e-2)" "unprognostic (1.67e-2)" "unprognostic (2.66e-1)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (1.41e-5)" "unprognostic (2.15e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (9.98e-3)" "unprognostic (3.59e-2)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" "unprognostic (1.34e-1)" 2.3 0.5 0.4 4.4 0.7 0.9 5.6 0.4 1.2 8.5 12.8 17.4 17.7 3.2 9.2 37.2 4.0 6.2 0.5 0.7 0.7 4.8 0.8 8.2 0.8 1.4 0.8 0.3 7.9 1.4 1.2 2.2 1.3 5.1 17.0 0.2 12.6 5.6 0.3 23.3 15.1 3.1 1.1 0.7 16.5 0.6 3.6 0.6 7.7 0.0 5.8 9.7 16.4 2.6 52.2 15.1 0.0 0.2 0.1 2.4 12.1 9.7 1.6 4.4 4.1 21.3 94.9 0.0 11.8 2.9 2.5 40.5 0.3 109.0 8.9 0.0 0.1 0.1 16.4 0.1 8.1 0.1 3.6 3.7 56.1 265.2 177.9 16.0 1.0 0.1 31.1 0.2 13.8 0.1 0.1 0.9 7.4 24.7 89.7 0.0 0.0 8.6 81.1 40.7 3.4 0.1 20.1 5.0 0.1 4.8 22.9 0.4 4.6 0.2 0.2 3.3 0.2 0.1 0.1 0.1 1.5 1.1 1.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.1 0.0 0.9 4.2 0.0 0.0 0.0 0.2 0.4 0.7 0.4 1.2 0.7 0.7 1.4 0.8 1.3 1.1 3.6 2.6 0.1 3.2 13.1 0.3 0.3 121.2 83.3 92.6 50.7 0.0 12.9 6.6 0.5 14.3 57.7 9.2 0.0 5.8 0.3 76.6 0.0 78.6 0.1 36.5 6.3 1.9 37.6 0.4 2.0 71.6 7.5 4.6 37.8 59.3 8.8 0.1 0.0 0.0 10.8 0.0 0.4 37.9 18.3 7.9 37.6 0.5 3.1 13.4 3.6 0.0 10.7 0.0 0.0 1.0 0.3 137.1 34.9 0.0 2.5 75.8 30.8 0.0 56.6 0.0 0.0 0.4 3.6 0.0 0.4 59.8 75.0 3.3 1.8 13.5 28.9 117.4 CDCP2 ENSG00000157211 "CUB domain containing protein 2" Q5VXM1 1 54132968-54153770 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA031143 Uncertain "Secreted - unknown location" NA NA "HPA031143: AB_10611819" "unprognostic (1.08e-1)" "unprognostic (5.16e-2)" "unprognostic (1.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-2)" "unprognostic (4.73e-2)" "unprognostic (5.29e-2)" "unprognostic (2.86e-2)" "unprognostic (2.57e-1)" "unprognostic (1.33e-1)" "unprognostic (1.67e-2)" "unprognostic (7.67e-6)" "unprognostic (2.37e-1)" "unprognostic (1.48e-1)" "unprognostic (5.12e-1)" "unprognostic (2.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDH11 "CAD11, OB" ENSG00000140937 "Cadherin 11" P55287 16 64943753-65126112 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 178.2;placenta: 122.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.0;Endometrial stromal cells: 125.0;Excitatory neurons: 122.2;Fibroblasts: 102.2;Microglial cells: 145.2;Oligodendrocyte precursor cells: 158.3;Oligodendrocytes: 106.3;Theca cells: 160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 246.5;BJ hTERT+: 139.3;fHDF/TERT166: 332.3;HSkMC: 217.4;PC-3: 291.2;U-2197: 194.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013072 Enhanced NA Yes 4800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB013072: AB_2533068" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (6.75e-2)" "prognostic unfavorable (2.48e-9)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (1.26e-1)" "unprognostic (5.07e-3)" 15.1 8.6 12.4 25.7 27.9 0.3 10.7 10.8 15.8 57.7 13.8 11.4 7.0 52.8 9.5 7.4 12.5 58.6 10.2 19.2 21.4 10.2 1.8 45.6 17.5 17.1 24.1 178.2 3.4 2.6 10.4 122.2 17.3 20.0 12.2 14.0 12.7 24.3 2.6 10.9 8.9 54.3 21.1 89.3 11.8 8.0 19.3 3.7 8.1 3.1 13.0 47.6 13.6 21.4 0.2 0.0 51.4 0.1 35.7 77.5 0.3 246.5 139.3 61.0 34.5 4.6 0.2 0.0 0.0 332.3 0.0 0.1 0.1 1.7 43.4 0.0 2.1 0.0 1.4 0.0 29.7 0.0 14.4 217.4 0.1 74.7 14.9 0.0 17.4 0.0 0.0 0.0 33.1 0.3 0.1 0.3 19.2 37.4 291.2 0.8 38.0 0.0 0.0 0.0 0.8 36.0 0.1 0.3 0.2 64.5 0.3 0.1 0.0 124.4 17.2 194.0 70.1 0.0 0.0 0.1 21.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 27.9 10.8 15.8 19.2 21.4 17.1 24.1 17.3 21.1 19.3 21.4 11.4 3.2 0.0 93.0 0.1 3.8 1.0 7.9 0.0 19.9 1.0 7.4 3.1 1.5 3.3 0.0 0.0 2.6 0.2 0.1 0.0 0.1 2.7 3.9 125.0 17.8 0.0 2.7 122.2 0.0 2.3 102.2 0.5 2.7 0.0 60.0 68.9 0.0 4.7 0.0 67.6 0.6 0.0 0.6 6.9 4.2 52.5 0.9 5.4 145.2 0.0 41.9 0.0 158.3 106.3 0.8 0.0 77.5 0.0 1.6 0.0 1.4 0.4 2.1 26.3 12.8 38.0 1.7 1.1 0.5 3.1 5.6 1.1 160.2 0.3 0.5 CDH13 CDHH ENSG00000140945 "Cadherin 13" P55290 16 82626965-83800640 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 57.1;skeletal muscle: 68.6;tongue: 57.7" "Group enriched" "Detected in many" 4 "Excitatory neurons: 328.8;Inhibitory neurons: 867.0;Oligodendrocyte precursor cells: 335.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.3" "Group enriched" "Detected in many" 6 "granulocytes: 2.2;monocytes: 4.3" "Cell line enhanced" "Detected in many" "LHCN-M2: 222.2;U-138 MG: 279.2;U-87 MG: 244.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001380, CAB025863" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 240000000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB025863: , HPA001380: AB_1078371" "unprognostic (2.50e-2)" "unprognostic (2.75e-2)" "unprognostic (5.61e-2)" "unprognostic (4.06e-1)" "unprognostic (4.88e-2)" "unprognostic (3.30e-3)" "unprognostic (3.01e-1)" "unprognostic (5.76e-2)" "unprognostic (3.49e-2)" "unprognostic (3.34e-1)" "unprognostic (2.21e-1)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.73e-6)" "unprognostic (5.16e-3)" "unprognostic (2.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" 20.3 2.8 18.7 3.8 21.5 0.6 10.0 0.0 14.3 42.5 0.0 5.0 1.5 47.2 3.3 9.5 7.6 5.0 57.1 10.5 3.3 5.0 1.8 16.1 1.4 1.5 6.5 3.1 0.6 2.4 0.5 6.0 0.6 3.5 6.2 1.5 4.9 7.2 68.6 21.1 2.3 29.9 6.3 2.1 1.7 1.8 22.9 1.8 5.8 57.7 1.9 7.1 19.4 3.2 10.2 0.0 3.6 0.5 63.2 60.6 0.1 47.1 51.9 53.6 23.1 0.1 0.4 0.1 8.5 138.5 26.0 89.1 1.0 70.7 79.8 0.0 0.2 0.1 31.4 0.1 36.4 0.0 0.4 7.9 59.9 107.8 130.4 83.9 26.7 0.0 0.2 0.5 222.2 0.5 0.1 0.2 10.6 0.0 19.4 0.0 57.7 0.0 46.2 0.4 0.1 0.1 84.4 0.3 0.1 103.5 0.8 0.1 43.1 279.2 22.7 1.6 43.0 0.2 0.1 0.2 244.0 0.2 70.1 2.2 0.5 1.4 0.0 2.1 0.0 0.5 0.0 0.0 0.5 0.5 0.0 0.0 1.1 0.0 4.3 0.3 0.0 0.2 18.7 21.5 0.0 14.3 10.5 3.3 1.5 6.5 0.6 6.3 22.9 3.2 125.4 0.0 0.5 11.1 0.3 70.7 28.7 32.3 25.0 3.0 1.0 5.8 86.9 0.0 2.6 3.7 0.0 0.1 0.9 2.1 7.9 0.4 44.5 1.0 27.1 49.2 1.8 0.0 328.8 0.0 0.2 9.7 0.0 0.7 0.0 0.0 29.6 0.3 0.6 5.0 867.0 1.6 0.0 1.9 13.3 43.3 0.3 1.4 8.8 17.8 0.0 0.4 0.0 335.8 65.0 0.1 1.4 0.0 0.0 36.7 0.0 1.3 0.8 0.4 0.0 51.0 22.7 2.9 0.6 3.3 18.8 0.1 1.2 0.7 0.1 6.4 CDH17 "cadherin, HPT-1" ENSG00000079112 "Cadherin 17" Q12864 8 94127162-94217303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "intestine: 314.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 569.4;Enteroendocrine cells: 108.4;Intestinal goblet cells: 183.7;Paneth cells: 408.6;Proximal enterocytes: 336.9;Undifferentiated cells: 241.6" "Group enriched" "Detected in many" 6 "colorectal cancer: 156.4;stomach cancer: 54.9" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "neutrophil: 16.0" "Lineage enriched" "Detected in single" 17 "granulocytes: 16.0" "Cell line enhanced" "Detected in some" "CACO-2: 98.8;OE19: 430.1;U-266/70: 157.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023614, HPA023616, CAB025143, HPA026556" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA 7500000 "Cluster 1: Neutrophils - Mixed function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Nucleoplasm "CAB025143: , HPA023614: AB_1845896, HPA023616: AB_1845895, HPA026556: AB_1845897" "unprognostic (2.08e-1)" "unprognostic (5.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (3.02e-1)" "unprognostic (3.06e-2)" "unprognostic (5.60e-2)" "unprognostic (3.38e-3)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.47e-2)" "unprognostic (3.74e-2)" "unprognostic (2.36e-1)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (7.33e-2)" "unprognostic (1.46e-2)" 0.9 0.2 0.7 28.8 0.5 2.7 0.5 1.1 0.8 0.1 1.9 260.9 314.2 1.3 0.8 1.7 0.3 3.0 0.6 0.5 0.2 0.8 0.3 0.2 1.5 0.3 0.1 0.5 1.7 0.0 0.0 0.2 0.3 1.2 246.7 0.5 0.9 1.6 0.5 0.6 270.6 9.3 0.1 5.5 2.5 0.6 0.2 0.3 0.7 0.1 1.8 0.8 0.1 0.7 0.2 18.5 0.2 0.4 0.0 0.4 1.6 0.2 0.3 0.2 0.3 98.8 3.5 0.3 0.3 0.0 0.1 1.0 0.3 0.3 0.3 0.2 1.1 0.1 0.8 0.6 0.3 0.2 4.3 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.4 1.5 0.1 0.7 0.5 1.3 0.3 430.1 0.5 0.3 0.0 2.8 0.3 0.2 1.3 1.2 0.4 0.4 0.5 0.4 0.7 0.9 0.0 0.6 0.7 1.2 0.5 157.2 0.3 0.2 0.3 0.3 0.6 2.9 0.9 1.4 0.2 0.8 0.1 0.3 0.2 0.1 0.5 0.8 0.2 0.3 16.0 0.7 0.5 0.4 0.2 0.2 0.7 0.5 1.1 0.8 0.5 0.2 0.3 0.1 0.3 0.1 0.2 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 569.4 0.0 0.3 1.0 0.0 0.0 0.0 108.4 0.0 0.5 0.0 0.0 0.1 2.6 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 183.7 0.0 0.0 0.5 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 408.6 0.0 0.2 0.0 336.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 2.1 0.0 241.6 0.1 CDH19 CDH7 ENSG00000071991 "Cadherin 19" Q9H159 18 66501083-66604138 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4;heart muscle: 37.1;intestine: 19.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 60.1;Melanocytes: 44.4;Oligodendrocyte precursor cells: 57.8;Oligodendrocytes: 192.6" "Cancer enriched" "Detected in some" 21 "melanoma: 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "SK-MEL-30: 35.9;WM-115: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056332 Uncertain NA NA 320000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA056332: AB_2683102" "unprognostic (1.63e-2)" "unprognostic (2.63e-2)" "unprognostic (4.26e-2)" "unprognostic (4.10e-2)" "unprognostic (2.51e-2)" "unprognostic (3.14e-2)" "unprognostic (1.93e-1)" "unprognostic (3.79e-1)" "unprognostic (1.02e-1)" "unprognostic (4.39e-2)" "unprognostic (9.33e-2)" "unprognostic (2.25e-2)" "unprognostic (4.58e-3)" "unprognostic (8.16e-3)" "unprognostic (8.21e-2)" "unprognostic (1.56e-5)" 2.3 4.2 3.3 3.1 11.4 0.1 1.3 4.4 7.2 6.7 0.0 19.4 2.2 0.9 1.6 3.0 1.9 2.6 37.1 4.7 5.3 0.4 4.1 1.2 0.1 8.8 7.4 1.1 1.2 0.1 0.4 2.9 7.5 4.2 2.8 0.1 3.4 4.1 4.2 1.9 5.4 1.7 2.7 2.2 4.9 0.7 7.7 0.1 1.0 1.2 0.0 5.2 5.9 18.4 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.1 0.0 0.0 35.9 0.1 1.5 0.0 0.0 0.1 0.3 0.2 0.1 4.0 0.2 0.0 0.1 0.1 63.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 11.4 4.4 7.2 4.7 5.3 8.8 7.4 7.5 2.7 7.7 18.4 0.0 0.0 0.0 1.0 0.0 1.1 0.3 0.2 2.8 0.0 1.1 0.3 9.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.6 0.0 0.0 2.8 0.0 0.0 60.1 0.0 0.0 0.0 0.0 12.5 0.3 0.0 0.0 0.5 0.0 2.0 0.6 1.0 0.2 5.3 0.1 44.4 0.0 0.0 0.0 0.0 57.8 192.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 3.6 2.7 0.9 0.3 0.3 0.0 0.1 0.0 0.0 0.4 CDH23 "CDHR23, DFNB12, USH1D" ENSG00000107736 "Cadherin related 23" Q9H251 10 71396920-71815947 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.6;ovary: 35.3" "Cell type enhanced" "Detected in many" "Early spermatids: 78.4;Late spermatids: 67.7;Microglial cells: 33.7;Muller glia cells: 90.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 26.8;non-classical monocyte: 38.1;plasmacytoid DC: 9.5" "Lineage enhanced" "Detected in many" "monocytes: 38.1" "Group enriched" "Detected in some" 4 "RT4: 13.4;SCLC-21H: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017232 Approved NA NA 950000 "Cluster 51: Monocytes - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "HPA017232: AB_1845903" "unprognostic (6.76e-2)" "unprognostic (2.86e-3)" "unprognostic (3.82e-2)" "unprognostic (3.13e-3)" "unprognostic (1.07e-1)" "unprognostic (5.52e-2)" "unprognostic (7.93e-2)" "unprognostic (2.88e-1)" "unprognostic (6.44e-3)" "unprognostic (4.67e-2)" "unprognostic (2.05e-1)" "unprognostic (9.23e-3)" "unprognostic (2.14e-3)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "prognostic favorable (3.40e-4)" 11.3 3.3 9.6 2.1 11.6 2.2 6.2 10.6 7.9 3.3 10.2 1.7 1.1 4.9 1.6 1.8 8.9 2.2 5.4 6.3 16.2 0.9 14.4 7.8 1.7 35.6 18.5 35.3 8.4 9.9 1.2 0.5 34.7 3.7 1.2 14.4 1.2 0.7 2.7 1.6 2.3 2.1 8.6 7.0 1.7 11.0 23.6 5.3 1.8 2.5 1.4 4.2 2.6 8.8 0.0 0.7 0.8 1.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.9 0.4 1.3 0.0 0.0 0.1 1.2 1.3 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.1 1.5 0.4 0.0 1.1 0.0 0.1 0.0 13.4 5.3 1.1 0.8 0.2 0.1 1.1 0.1 2.2 0.0 0.0 1.1 0.0 0.0 0.6 0.0 0.2 1.5 1.0 0.0 0.0 6.0 5.1 0.1 26.8 0.4 0.0 0.2 0.1 4.9 0.0 0.2 0.6 6.1 0.0 38.1 9.5 0.0 2.9 9.6 11.6 10.6 7.9 6.3 16.2 35.6 18.5 34.7 8.6 23.6 8.8 8.2 0.0 0.6 9.4 1.1 0.8 4.1 0.3 0.6 1.9 0.2 1.1 4.7 0.0 1.0 1.8 0.0 1.5 11.5 0.9 0.0 0.4 78.4 1.9 0.7 10.0 7.2 0.0 1.1 0.4 4.4 3.4 1.1 0.3 0.0 0.4 7.9 20.4 2.2 0.0 2.7 1.1 0.0 12.2 11.6 67.7 2.5 15.0 7.2 33.7 10.6 90.7 3.1 1.5 8.5 0.2 7.5 0.7 0.4 2.6 1.6 0.8 0.7 4.2 6.6 5.1 1.7 3.4 1.0 0.0 1.1 0.3 1.0 0.2 0.7 3.6 CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 311.9;Endothelial cells: 206.1;Hepatic stellate cells: 185.6;Late spermatids: 84.6;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 752.5;TIME: 655.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" 84.5 13.8 16.3 14.9 15.9 0.2 71.4 15.1 16.6 16.2 11.3 16.8 7.9 19.9 8.6 12.4 17.1 29.7 84.4 13.8 14.6 19.1 24.0 95.0 13.1 16.7 16.6 8.1 7.7 10.3 7.4 235.9 17.9 11.6 10.2 1.3 12.0 9.1 41.8 16.7 17.0 27.8 15.5 20.4 13.3 10.5 22.6 5.2 37.5 58.9 7.9 22.1 14.2 15.5 0.5 0.6 4.6 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 119.8 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 752.5 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 15.7 0.0 2.4 0.0 0.1 655.1 0.0 0.9 0.1 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 15.9 15.1 16.6 13.8 14.6 16.7 16.6 17.9 15.5 22.6 15.5 311.9 0.0 6.2 1.3 0.7 4.1 0.0 0.0 1.8 0.0 1.0 2.7 17.9 5.7 0.6 1.8 0.0 6.6 0.5 0.0 0.0 0.2 33.5 0.5 0.6 206.1 0.0 10.7 0.1 0.0 48.9 7.1 0.0 1.3 3.8 0.0 185.6 1.7 2.3 0.0 0.1 0.0 0.0 35.7 6.3 84.6 6.2 1.2 12.4 28.1 0.1 0.3 0.0 0.5 0.1 0.0 0.0 2.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.4 10.9 0.3 0.3 3.0 80.7 1.5 3.0 0.1 0.2 CDH8 ENSG00000150394 "Cadherin 8" P55286 16 61647242-62037035 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 22.4" "Group enriched" "Detected in some" 13 "Excitatory neurons: 220.8;Inhibitory neurons: 236.4;Oligodendrocytes: 145.7" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 7.0;fHDF/TERT166: 6.3;HaCaT: 14.4;LHCN-M2: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014908, HPA076441" Approved Approved "Plasma membrane" NA NA 870000 "Cluster 65: Brain - Ion transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA014908: AB_1845908, HPA076441: " "unprognostic (1.91e-1)" "unprognostic (2.41e-1)" "unprognostic (4.02e-2)" "unprognostic (7.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.26e-2)" "unprognostic (1.83e-1)" "unprognostic (8.71e-2)" "unprognostic (3.66e-2)" "unprognostic (5.41e-2)" "unprognostic (2.85e-1)" "unprognostic (6.59e-2)" "unprognostic (2.91e-4)" "unprognostic (6.02e-2)" "unprognostic (4.06e-1)" "unprognostic (2.26e-1)" "unprognostic (1.06e-1)" 0.1 0.1 7.2 0.0 9.9 0.0 0.3 0.0 22.4 0.4 0.0 0.2 0.3 0.1 0.2 0.1 0.0 0.2 0.2 16.3 5.7 0.0 0.0 0.1 0.0 6.4 9.8 1.7 0.0 0.1 0.7 0.3 18.4 0.4 0.1 2.2 0.4 5.0 0.4 0.1 0.2 0.4 7.6 0.0 0.1 0.3 9.1 0.5 0.1 0.9 0.0 0.4 0.1 2.5 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 6.3 0.0 14.4 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.4 0.0 17.3 0.0 0.0 0.0 1.3 0.0 1.3 0.0 0.0 1.1 0.0 1.9 0.1 0.1 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 9.9 0.0 22.4 16.3 5.7 6.4 9.8 18.4 7.6 9.1 2.5 0.4 0.0 0.5 3.9 0.0 0.1 0.8 1.3 1.2 15.1 0.1 0.9 1.0 0.0 0.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 4.9 0.1 0.1 0.5 0.0 0.0 220.8 0.0 0.2 0.8 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 236.4 0.0 2.0 0.0 0.0 1.3 0.0 0.1 0.0 8.4 0.0 0.7 0.0 7.5 145.7 0.0 0.0 0.4 0.0 0.3 0.0 0.2 2.7 0.7 0.0 0.7 4.7 1.3 2.5 0.5 0.1 0.3 0.1 0.1 0.0 0.8 CDH9 ENSG00000113100 "Cadherin 9" Q9ULB4 5 26880597-27121150 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.8;kidney: 5.7" "Group enriched" "Detected in some" 33 "Excitatory neurons: 307.2;Inhibitory neurons: 459.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "amygdala: 6.8;basal ganglia: 4.3;cerebral cortex: 6.4;hippocampal formation: 5.8" "Immune cell enhanced" "Detected in some" "neutrophil: 4.9" "Group enriched" "Detected in many" 5 "B-cells: 2.3;granulocytes: 4.9" "Cell line enhanced" "Detected in some" "K-562: 7.3;NTERA-2: 10.1;U-698: 4.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA007167 Approved Approved "Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA007167: AB_1078489" "unprognostic (1.49e-1)" "unprognostic (2.27e-4)" 0.3 0.2 6.8 0.6 4.3 1.9 0.3 0.0 6.4 0.0 0.0 0.4 0.5 0.5 0.6 0.4 0.2 0.4 0.1 5.8 0.0 5.7 0.1 0.3 1.0 0.0 0.0 0.3 0.6 0.1 0.0 0.4 0.0 0.5 0.6 1.3 0.2 0.1 0.1 1.0 0.8 0.4 0.0 0.4 0.5 2.2 0.0 0.2 1.0 0.1 1.0 0.3 0.0 0.9 1.9 0.7 0.4 0.6 0.2 0.0 1.2 0.0 0.3 0.1 0.2 0.0 0.7 1.0 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.1 0.2 0.4 0.6 2.2 0.0 0.0 1.2 0.2 0.3 0.0 0.0 0.0 0.1 0.6 7.3 1.8 0.0 1.3 0.6 0.4 10.1 0.2 0.4 0.2 0.2 0.3 0.3 0.4 2.2 0.2 0.0 0.3 0.3 1.8 0.3 0.7 1.3 0.1 0.7 0.6 0.2 2.0 0.8 4.6 0.6 0.8 0.6 1.2 0.1 0.2 0.1 0.4 0.3 2.3 0.1 0.1 0.1 1.6 0.1 0.3 4.9 0.0 0.7 0.5 0.5 0.6 6.8 4.3 0.0 6.4 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 10.4 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 307.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 459.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 11.6 5.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDHR1 "CORD15, KIAA1775, PCDH21, RP65" ENSG00000148600 "Cadherin related family member 1" Q96JP9 10 84194537-84219621 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 313.8;skin 1: 214.0" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 379.5;Rod photoreceptor cells: 240.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "NK-cell: 7.5" "Lineage enriched" "Detected in single" 12 "NK-cells: 7.5" "Cell line enhanced" "Detected in some" "HAP1: 10.2;HEK 293: 5.2;HEL: 6.3;K-562: 4.6;NTERA-2: 4.4;RPTEC TERT1: 16.3" "Region enriched" "Detected in many" 21 "olfactory bulb: 333.0" "Low region specificity" "Detected in all" HPA036819 Enhanced "Intracellular and membrane" NA NA 55000 "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA036819: AB_10671750" "unprognostic (8.91e-4)" "unprognostic (5.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.71e-2)" "unprognostic (2.63e-2)" "unprognostic (3.03e-2)" "unprognostic (6.40e-2)" "unprognostic (7.77e-2)" "unprognostic (1.41e-1)" "unprognostic (2.67e-1)" "unprognostic (6.69e-4)" "unprognostic (1.90e-1)" "unprognostic (5.51e-3)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (4.56e-3)" "unprognostic (5.07e-2)" 0.2 1.9 7.4 1.0 18.3 0.4 4.5 2.3 8.7 5.3 46.2 29.2 0.1 0.6 4.4 10.7 0.5 0.4 1.2 6.6 7.5 0.4 0.5 0.2 0.9 13.4 2.3 1.1 0.1 0.0 3.0 0.2 13.9 1.4 53.2 313.8 1.5 4.2 1.0 214.0 12.2 1.2 0.1 7.0 0.2 0.3 3.2 3.3 0.2 0.0 1.1 0.1 3.5 3.5 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 10.2 2.0 0.0 0.0 5.2 6.3 0.0 0.0 0.2 0.0 0.2 0.0 2.2 0.0 0.7 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.5 4.4 0.0 0.0 0.0 0.0 1.4 16.3 0.0 3.4 0.8 0.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.1 7.4 18.3 2.3 8.7 6.6 7.5 13.4 2.3 13.9 0.1 3.2 3.5 0.0 0.0 0.5 1.3 0.1 51.2 0.3 1.4 3.4 24.1 0.0 0.1 1.8 0.0 0.7 0.0 379.5 0.0 2.1 47.9 0.0 0.1 0.0 2.7 0.7 1.8 12.7 0.0 4.9 0.0 0.0 0.6 0.0 3.1 0.0 3.7 0.4 0.4 0.0 5.0 7.7 46.9 0.0 0.3 5.2 0.2 0.0 0.1 3.6 1.0 0.0 26.3 1.0 7.5 4.4 0.0 31.2 0.0 0.7 0.3 23.0 0.2 0.1 240.4 0.0 0.2 0.3 0.6 0.3 3.0 67.5 0.0 3.0 0.3 52.9 0.2 CDHR4 "CDH29, VLLR9392" ENSG00000187492 "Cadherin related family member 4" A6H8M9 3 49790732-49799873 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "fallopian tube: 59.4" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 74.2;Respiratory ciliated cells: 160.4" "Cancer enriched" "Detected in some" 6 "endometrial cancer: 6.8" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.3;HeLa: 1.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.2" HPA076277 Enhanced "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA076277: AB_2732306" "unprognostic (1.50e-4)" "unprognostic (4.87e-2)" "unprognostic (6.00e-2)" "unprognostic (2.00e-3)" "unprognostic (2.37e-2)" "unprognostic (2.45e-3)" "unprognostic (6.35e-7)" "unprognostic (1.17e-1)" "unprognostic (1.13e-2)" "unprognostic (1.12e-1)" "unprognostic (9.61e-2)" "unprognostic (2.35e-1)" "unprognostic (9.07e-11)" "unprognostic (2.65e-1)" "unprognostic (3.70e-2)" "unprognostic (1.13e-2)" "unprognostic (2.37e-1)" 0.5 0.1 0.6 0.1 0.6 0.2 0.2 0.4 0.3 5.5 1.0 0.5 0.1 1.7 0.4 0.1 59.4 0.1 0.2 0.6 0.7 0.2 0.1 7.4 0.0 2.7 6.1 0.2 0.0 0.0 0.1 0.1 3.4 0.3 0.1 0.0 0.2 0.2 0.2 1.3 0.1 0.2 1.2 0.0 0.1 7.5 0.8 0.0 0.2 0.0 0.0 0.2 0.3 1.0 0.1 0.5 0.1 0.0 0.1 1.3 0.1 0.1 0.0 0.2 0.3 0.0 0.8 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.5 0.3 0.0 0.1 0.1 0.2 0.4 0.2 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.2 0.7 0.0 0.6 0.4 0.0 1.9 2.0 0.2 0.1 0.7 0.1 0.2 0.1 0.1 0.7 0.4 0.1 0.1 1.0 0.5 0.1 0.2 0.1 3.9 0.6 0.6 0.4 0.3 0.6 0.7 2.7 6.1 3.4 1.2 0.8 1.0 0.2 0.0 3.4 0.0 0.0 0.1 0.1 4.3 0.0 0.0 0.1 0.1 0.4 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 74.2 0.9 0.5 0.0 0.0 0.1 0.2 0.1 0.9 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 20.3 0.0 0.0 4.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.1 160.4 0.0 0.0 0.2 1.7 4.8 0.8 0.0 0.0 0.0 0.2 0.1 0.2 0.1 CDHR5 "FLJ20219, MU-PCDH, MUCDHL, MUPCDH" ENSG00000099834 "Cadherin related family member 5" Q9HBB8 11 616577-626078 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 296.8;liver: 129.8" "Group enriched" "Detected in some" 7 "Distal enterocytes: 811.5;Paneth cells: 732.4;Proximal enterocytes: 2545.8" "Cancer enhanced" "Detected in many" "liver cancer: 61.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 13.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009081, HPA009173, CAB025004" Enhanced "Intracellular and membrane" NA NA 190000000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "CAB025004: , HPA009081: AB_1079428, HPA009173: AB_1079429" "unprognostic (7.65e-2)" "unprognostic (1.42e-1)" "unprognostic (9.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-3)" "unprognostic (4.89e-2)" "unprognostic (3.85e-2)" "unprognostic (5.75e-2)" "unprognostic (6.36e-2)" "unprognostic (7.95e-2)" "unprognostic (5.07e-2)" "unprognostic (5.01e-2)" "unprognostic (3.90e-1)" "unprognostic (8.85e-2)" "unprognostic (2.29e-1)" "unprognostic (2.14e-2)" 0.1 0.9 0.2 4.0 0.6 0.1 0.4 0.5 0.4 0.1 2.2 102.2 241.2 0.2 0.0 0.3 0.3 3.9 0.0 0.2 0.0 44.9 129.8 0.2 0.2 0.2 0.1 0.2 1.8 0.0 0.6 0.0 0.3 0.1 51.9 0.1 0.0 0.1 0.1 0.1 296.8 2.7 0.0 0.1 4.3 0.3 0.3 0.0 0.1 0.0 0.0 0.1 0.1 0.8 0.0 0.3 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.3 13.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.5 0.4 0.2 0.0 0.2 0.1 0.3 0.0 0.3 0.8 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 11.5 0.0 1.8 0.0 0.0 1.4 811.5 13.7 0.3 2.8 0.1 0.2 0.1 92.8 0.0 0.0 1.3 0.0 0.0 33.6 0.4 13.4 0.0 4.6 126.1 0.1 0.0 0.1 193.2 0.0 4.3 0.0 18.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 732.4 0.0 0.0 0.0 2545.8 107.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 154.6 0.0 CDK13 "CDC2L, CDC2L5, CHED, KIAA1791" ENSG00000065883 "Cyclin dependent kinase 13" Q14004 7 39950121-40099580 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 179.0;Oligodendrocyte precursor cells: 171.9;Oligodendrocytes: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059241 Uncertain Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Golgi apparatus, Cytosol" "HPA059241: AB_2683956" "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (2.72e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (4.18e-3)" "unprognostic (3.42e-2)" "unprognostic (8.09e-2)" "unprognostic (1.13e-2)" "unprognostic (3.77e-2)" "unprognostic (8.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.21e-1)" "unprognostic (3.33e-2)" "unprognostic (3.53e-1)" "unprognostic (3.53e-2)" 11.4 10.2 8.8 14.6 10.8 28.1 11.1 19.3 9.9 12.8 6.7 11.9 10.5 13.6 14.2 14.7 15.0 12.7 10.4 8.1 10.7 12.7 15.9 12.1 21.7 10.5 8.5 20.1 12.8 17.2 8.0 13.6 8.6 11.2 13.6 19.7 12.9 11.8 11.2 12.0 12.0 12.0 7.2 16.6 12.3 19.0 10.1 19.6 20.6 14.0 20.2 13.4 10.0 14.9 28.4 16.6 28.2 27.0 24.9 24.1 19.3 22.1 23.8 19.8 24.6 17.8 19.1 51.0 12.6 23.4 34.8 33.6 23.4 19.4 29.0 25.3 17.3 22.8 20.0 16.0 23.7 34.8 23.5 14.3 25.5 22.6 30.0 22.6 23.6 23.1 39.0 34.3 20.7 14.7 28.0 24.9 40.8 20.0 19.1 30.5 18.5 20.5 18.5 28.1 20.0 28.8 27.6 59.8 19.9 36.7 24.6 43.0 28.3 27.0 26.0 17.6 30.5 28.3 26.0 41.2 19.8 30.9 35.4 7.8 2.2 4.0 4.1 1.9 2.8 6.4 3.8 3.0 1.3 10.5 3.8 3.9 5.9 4.3 3.1 3.3 3.9 1.3 8.8 10.8 19.3 9.9 8.1 10.7 10.5 8.5 8.6 7.2 10.1 14.9 47.6 44.8 72.0 131.6 49.7 21.4 18.5 15.9 29.0 47.8 36.7 27.7 30.9 25.8 37.1 31.3 70.9 13.7 91.0 23.1 7.9 20.4 13.9 54.3 51.4 30.9 18.7 5.9 179.0 15.4 9.1 31.7 30.1 72.6 17.1 95.5 19.2 23.7 13.2 37.0 166.2 17.6 14.2 23.8 17.4 9.2 26.1 31.6 14.2 145.2 27.9 22.4 53.5 171.9 199.6 28.6 12.9 17.7 50.1 21.8 15.2 12.7 32.8 69.4 6.6 38.5 32.0 36.1 33.4 34.7 26.1 12.2 49.7 56.8 20.1 25.0 CDKN2A "ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf" ENSG00000147889 "Cyclin dependent kinase inhibitor 2A" "P42771, Q8N726" 9 21967752-21995301 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.7;pituitary gland: 33.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 170.1;Club cells: 145.9;Early spermatids: 227.5;Late spermatids: 447.9;Pancreatic endocrine cells: 417.7;Respiratory ciliated cells: 221.9" "Cancer enhanced" "Detected in all" "cervical cancer: 49.9;ovarian cancer: 57.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 37.4" "Group enriched" "Detected in many" 6 "B-cells: 15.6;T-cells: 37.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 289.2;HEK 293: 389.7;HeLa: 311.1;SK-MEL-30: 318.7" "Low region specificity" "Detected in some" "CAB000093, CAB000445, CAB018232, HPA047838" Enhanced Supported Nucleoli NA NA 18000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoli "CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: AB_2680174" "unprognostic (3.41e-2)" "unprognostic (4.51e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (1.82e-7)" "unprognostic (5.22e-2)" "prognostic favorable (5.19e-4)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.76e-7)" "unprognostic (9.41e-2)" "unprognostic (1.22e-2)" "unprognostic (3.05e-2)" "unprognostic (3.55e-1)" 3.7 10.1 7.4 1.7 8.3 1.3 3.1 5.9 8.5 1.1 31.7 1.9 0.8 0.7 1.0 7.4 2.2 0.5 0.7 6.7 6.4 0.5 0.7 2.3 2.1 7.4 5.8 0.8 1.5 2.1 33.7 2.6 7.2 2.1 0.7 0.1 1.6 1.6 0.6 0.9 3.6 0.3 6.2 5.5 3.9 14.8 8.0 2.1 1.3 0.0 2.5 2.4 2.3 9.2 11.8 0.0 1.7 82.2 0.8 0.9 39.1 15.9 0.0 111.7 196.0 19.1 289.2 47.1 167.7 9.5 0.0 36.0 34.3 211.0 91.4 212.2 389.7 0.1 311.1 13.6 8.8 22.4 17.3 21.2 0.0 112.2 61.9 236.3 11.7 0.0 0.1 188.4 105.7 0.8 1.9 0.0 2.6 24.2 185.9 0.2 80.2 166.3 23.4 0.0 195.2 14.0 219.9 36.6 318.7 9.4 42.8 0.7 39.5 0.9 2.6 0.3 0.5 84.7 49.6 177.8 0.2 62.9 1.0 1.5 2.1 0.3 9.9 1.3 14.1 11.1 11.4 17.6 0.3 15.6 0.6 6.7 0.5 0.8 4.2 0.0 37.4 3.6 7.4 8.3 5.9 8.5 6.7 6.4 7.4 5.8 7.2 6.2 8.0 9.2 1.6 0.0 0.0 1.0 11.5 1.8 2.3 170.1 0.0 0.6 6.1 10.4 4.2 0.0 145.9 11.0 0.0 27.9 6.2 8.1 0.0 29.7 227.5 36.4 6.7 2.6 70.9 0.0 1.2 26.4 43.8 7.7 0.0 6.2 4.5 4.6 1.4 0.3 7.6 0.0 3.5 6.3 122.1 10.5 4.2 447.9 3.1 2.9 8.8 7.5 16.2 0.9 5.2 4.5 6.6 417.7 12.1 1.9 38.7 35.4 32.8 0.0 221.9 0.1 0.0 1.1 20.8 7.2 6.2 7.2 0.4 9.2 12.7 11.0 3.8 54.4 CDNF ARMETL1 ENSG00000185267 "Cerebral dopamine neurotrophic factor" Q49AH0 10 14819245-14838575 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 25.9;tongue: 20.3" "Group enriched" "Detected in many" 9 "Early spermatids: 99.9;Late spermatids: 274.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "RPMI-8226: 8.4;U-266/70: 4.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA044587 Uncertain "Secreted in other tissues" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA044587: AB_10795881" "unprognostic (2.80e-3)" "unprognostic (2.51e-2)" "unprognostic (6.20e-2)" "unprognostic (2.62e-1)" "unprognostic (4.47e-2)" "unprognostic (2.62e-1)" "unprognostic (5.32e-2)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (4.14e-2)" "unprognostic (1.25e-1)" "unprognostic (4.81e-2)" "unprognostic (1.08e-1)" "unprognostic (8.66e-2)" "unprognostic (6.93e-2)" "unprognostic (2.31e-2)" "unprognostic (3.62e-1)" 2.5 2.4 0.8 0.5 1.1 0.4 3.6 1.2 1.2 1.7 1.3 1.2 1.8 2.0 3.8 1.5 3.9 1.5 2.2 0.9 1.3 3.4 8.6 1.1 1.5 1.2 1.3 2.8 5.4 2.9 2.0 0.5 1.4 2.9 1.1 1.7 3.8 1.8 25.9 5.0 1.1 0.7 1.3 1.0 2.5 10.1 1.0 1.2 4.1 20.3 1.5 1.2 1.3 1.7 0.4 0.4 1.0 0.4 2.2 1.9 0.1 0.8 1.7 0.7 0.5 0.6 0.9 3.3 0.7 0.5 0.0 0.3 0.1 0.0 0.7 0.3 1.0 0.5 0.5 0.2 1.4 0.2 0.0 1.7 1.2 0.3 1.3 1.1 0.7 1.5 1.0 2.1 1.0 0.9 0.4 0.3 0.6 0.6 0.2 0.6 0.4 8.4 0.4 0.1 0.8 1.3 0.2 0.5 1.4 0.5 1.2 0.3 0.5 0.1 0.3 1.4 0.1 4.5 1.2 0.5 0.6 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.3 0.3 0.5 0.3 0.3 1.2 0.8 0.0 0.9 0.1 0.4 1.6 0.2 0.8 1.1 1.2 1.2 0.9 1.3 1.2 1.3 1.4 1.3 1.0 1.7 0.5 0.0 2.2 2.0 2.3 2.0 1.4 0.7 4.0 1.0 2.3 2.2 2.0 2.8 2.3 0.0 2.1 0.9 0.6 0.1 3.9 1.0 99.9 4.2 0.8 0.9 0.0 0.4 1.0 3.6 1.6 2.1 5.1 0.6 0.0 0.7 0.4 5.8 0.4 0.0 1.4 0.5 2.0 1.2 0.6 274.2 1.2 0.4 0.0 1.0 0.2 3.1 3.1 1.5 3.3 0.6 0.5 1.2 4.8 0.9 1.4 5.2 5.8 1.0 0.0 3.2 1.8 18.9 7.5 1.6 0.1 1.4 1.2 0.5 0.7 1.2 CDON "CDO, CDON1, ORCAM" ENSG00000064309 "Cell adhesion associated, oncogene regulated" Q4KMG0 11 125955796-126063335 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 58.3;Fibroblasts: 23.5;Inhibitory neurons: 49.5;Muller glia cells: 39.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 23.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 28.4;ASC diff: 32.7;RH-30: 48.9;SuSa: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB012422, HPA017377" Uncertain NA NA 15000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB012422: AB_2260246, HPA017377: AB_1846453" "prognostic favorable (1.35e-4)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" "unprognostic (1.25e-4)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (5.77e-3)" "unprognostic (2.78e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (5.39e-2)" "unprognostic (1.51e-1)" "unprognostic (5.83e-3)" "unprognostic (1.86e-4)" 12.6 0.7 1.9 1.6 2.0 0.0 5.1 23.0 4.0 7.9 1.2 12.4 1.0 14.0 2.1 1.7 14.2 4.8 4.0 1.6 1.8 0.8 1.2 2.7 1.1 2.2 1.9 20.6 1.2 2.5 3.0 2.7 2.7 1.3 1.6 10.1 1.7 2.8 1.2 9.9 2.9 17.0 0.5 0.7 4.6 3.6 2.3 2.8 18.5 1.6 1.5 2.5 3.0 2.1 1.6 3.2 28.4 2.8 32.7 14.5 0.4 0.5 2.9 0.9 0.3 1.1 9.4 1.4 6.8 0.6 3.3 0.4 7.1 1.0 0.8 5.5 6.3 0.5 6.5 2.9 6.4 0.4 1.8 4.5 1.2 0.6 0.0 12.2 0.3 4.8 0.1 1.9 2.7 0.4 3.6 1.0 2.6 0.8 3.7 1.1 48.9 0.9 1.7 0.5 2.4 9.6 3.7 0.3 4.7 23.8 2.4 1.0 0.5 3.2 2.2 6.3 3.3 2.5 5.5 0.2 2.0 1.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.0 23.0 4.0 1.6 1.8 2.2 1.9 2.7 0.5 2.3 2.1 3.0 6.4 9.9 11.1 0.1 15.2 1.4 0.8 2.2 5.1 5.4 1.9 5.2 2.8 5.6 0.0 16.7 0.6 0.1 0.2 0.0 1.3 3.1 1.7 0.5 3.0 7.7 0.4 58.3 0.6 0.4 23.5 1.5 1.1 0.0 1.8 1.1 2.1 0.3 0.0 49.5 0.3 0.0 0.0 7.6 2.7 14.9 0.2 3.6 2.8 0.1 39.3 0.0 14.1 5.8 2.4 0.4 11.3 0.8 1.1 0.6 0.5 4.2 4.6 0.0 2.9 2.7 1.8 3.8 0.5 10.7 0.7 0.6 13.2 0.4 1.6 CDSN D6S586E ENSG00000204539 Corneodesmosin 6 31115087-31120446 "Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "skin 1: 696.5" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 2.6;Gastric mucus-secreting cells: 2.0;Glandular and luminal cells: 7.1;granulocytes: 4.5;Suprabasal keratinocytes: 5.3" "Group enriched" "Detected in some" 8 "head and neck cancer: 2.4;melanoma: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "A-431: 1.6" "Region enhanced" "Detected in some" "cerebral cortex: 1.5" "Not detected" "Not detected" "HPA044730, HPA054184" Enhanced "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA044730: AB_10964923, HPA054184: AB_2682409" "unprognostic (1.46e-1)" "unprognostic (6.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-1)" "unprognostic (3.44e-2)" "unprognostic (8.80e-2)" "unprognostic (8.13e-2)" "unprognostic (3.92e-4)" "unprognostic (3.92e-3)" "unprognostic (1.74e-4)" "unprognostic (6.34e-2)" "unprognostic (2.75e-1)" "unprognostic (2.22e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.1 0.0 0.1 3.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 696.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.9 0.4 2.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 7.1 4.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 1.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.2 CEACAM16 DFNA4B ENSG00000213892 "CEA cell adhesion molecule 16, tectorial membrane component" Q2WEN9 19 44699151-44710718 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "pancreas: 2.0" "Group enriched" "Detected in some" 7 "Bipolar cells: 7.7;Skeletal myocytes: 20.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045075 Uncertain "Secreted in other tissues" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA045075: AB_10959617" "unprognostic (1.27e-1)" "unprognostic (3.73e-1)" "unprognostic (3.12e-1)" "unprognostic (3.32e-2)" "unprognostic (4.72e-1)" "unprognostic (1.42e-2)" "unprognostic (7.76e-2)" "unprognostic (3.59e-2)" "unprognostic (7.81e-3)" "unprognostic (3.88e-2)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "unprognostic (1.86e-1)" "unprognostic (7.94e-2)" 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 20.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 CEACAM18 ENSG00000213822 "CEA cell adhesion molecule 18" A8MTB9 19 51478622-51490952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 26 "intestine: 10.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.8;stomach cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "CACO-2: 4.3;OE19: 3.5;RT4: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA059487 Uncertain Approved Midbody Yes NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Midbody "HPA059487: AB_2684036" "unprognostic (1.12e-1)" "unprognostic (1.87e-2)" "unprognostic (1.00e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CEACAM19 CEAL1 ENSG00000186567 "CEA cell adhesion molecule 19" Q7Z692 19 44662278-44684359 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.9;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 12.2;RPTEC TERT1: 15.8;TIME: 20.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.1" "HPA014462, HPA052865" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Nucleoli, Mitochondria" Nucleoplasm "HPA014462: AB_2669006, HPA052865: AB_2681976" "unprognostic (2.91e-1)" "unprognostic (5.29e-3)" "unprognostic (6.96e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-2)" "unprognostic (8.43e-2)" "unprognostic (5.22e-2)" "unprognostic (1.15e-2)" "unprognostic (9.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.77e-1)" "unprognostic (3.26e-9)" "unprognostic (8.01e-3)" "unprognostic (9.62e-2)" "unprognostic (1.31e-1)" "unprognostic (2.70e-1)" 3.9 5.6 3.7 1.3 3.7 1.5 3.8 4.9 5.1 7.0 3.5 4.7 3.0 5.2 1.7 5.1 6.8 2.4 11.7 4.0 3.8 9.4 8.2 8.2 1.1 2.8 3.0 6.6 8.9 1.5 7.0 2.2 2.7 7.8 3.4 2.4 5.7 3.1 13.8 12.4 3.8 3.1 1.9 3.5 4.6 5.7 3.7 0.9 6.5 3.4 2.2 4.2 8.7 4.7 5.1 10.3 1.5 1.0 3.5 4.0 3.8 2.8 4.2 0.9 1.8 0.4 1.1 0.1 1.0 3.8 1.0 6.2 2.6 1.1 0.8 1.5 5.8 0.1 6.7 1.7 3.6 0.2 1.0 1.3 10.0 2.6 6.1 12.2 2.4 0.7 0.3 0.3 1.4 1.2 0.0 0.6 0.9 1.4 1.1 0.0 1.8 0.2 15.8 1.2 1.9 0.5 1.1 1.1 0.9 1.4 1.4 0.3 20.9 0.4 6.8 1.5 0.9 0.1 0.3 0.0 0.5 2.0 1.7 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.7 3.7 4.9 5.1 4.0 3.8 2.8 3.0 2.7 1.9 3.7 4.7 3.6 3.2 2.2 2.0 0.0 2.0 0.9 2.1 1.2 2.9 1.9 1.5 4.5 1.5 2.4 0.0 0.0 0.2 0.1 2.1 0.0 1.6 3.8 0.9 0.9 4.1 1.8 0.0 7.9 3.3 0.2 1.0 3.6 2.4 0.0 0.8 4.6 2.6 0.3 0.0 6.1 2.3 4.1 0.6 0.8 1.9 3.1 0.5 0.0 1.9 0.4 0.3 1.0 2.0 2.4 4.5 2.6 2.6 0.0 1.8 1.2 0.4 1.8 0.6 0.0 8.8 1.7 3.1 0.9 1.2 6.0 0.0 0.2 1.6 2.5 0.9 CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 981.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 1389.2;Intestinal goblet cells: 395.0;Paneth cells: 777.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 1007.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 56.9" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 23000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB000021: , CAB000022: AB_2335697, HPA011041: AB_1078481, HPA019758: AB_1846326" "unprognostic (1.54e-2)" "unprognostic (7.59e-2)" "unprognostic (5.49e-3)" "unprognostic (1.80e-1)" "unprognostic (1.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.11e-1)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (8.67e-9)" "unprognostic (2.92e-1)" "unprognostic (2.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-1)" 3.2 0.1 0.0 185.6 0.0 0.2 4.0 0.3 0.1 38.5 0.2 981.2 22.7 1.3 0.2 232.0 0.8 0.8 0.1 0.1 0.0 0.9 0.2 30.2 0.1 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.5 942.7 0.0 29.2 3.3 0.1 3.5 61.4 28.7 0.0 0.1 163.2 0.3 0.1 0.2 1.0 0.0 36.9 10.4 71.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.3 56.9 1.1 0.2 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 32.1 4.1 0.0 2.7 0.0 1.0 12.3 0.0 0.0 0.1 0.0 0.4 0.0 34.8 0.0 0.0 0.0 0.0 1389.2 0.0 3.4 0.4 0.0 0.0 0.2 65.7 0.0 0.1 0.9 0.0 0.4 22.4 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 395.0 4.1 0.0 0.4 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 21.3 777.3 0.0 0.1 16.5 10.2 0.0 4.5 0.0 0.0 0.1 0.4 0.8 0.5 1.9 0.0 0.0 1.2 0.0 192.3 124.4 CEACAM6 "CD66c, NCA" ENSG00000086548 "CEA cell adhesion molecule 6" P40199 19 41750977-41772211 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 181.5;esophagus: 195.2;intestine: 220.3;lung: 286.7;salivary gland: 177.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 942.3;Club cells: 322.1;Distal enterocytes: 640.1;Paneth cells: 391.1;Urothelial cells: 182.3" "Group enriched" "Detected in many" 4 "cervical cancer: 139.4;colorectal cancer: 500.8;lung cancer: 344.1;pancreatic cancer: 437.5;stomach cancer: 231.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 11 "OE19: 1799.0" "CAB008370, HPA011041" Enhanced NA NA 86000000 "Cluster 24: B-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB008370: AB_592067, HPA011041: AB_1078481" "unprognostic (1.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.62e-2)" "unprognostic (8.22e-2)" "unprognostic (1.39e-1)" "unprognostic (9.06e-3)" "unprognostic (2.32e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "unprognostic (5.22e-2)" "unprognostic (3.70e-3)" "unprognostic (1.93e-1)" "unprognostic (2.42e-4)" "unprognostic (4.08e-1)" "unprognostic (8.71e-3)" "unprognostic (2.85e-1)" "unprognostic (7.68e-2)" 2.0 0.4 0.3 29.7 1.2 181.5 2.7 0.6 0.6 39.2 0.0 195.0 33.0 0.6 1.8 195.2 8.2 130.1 0.2 0.2 0.0 0.3 0.7 286.7 0.3 0.3 0.1 0.4 5.2 0.1 0.3 0.5 0.2 2.4 220.3 0.0 177.6 1.4 0.1 6.8 24.4 6.6 0.0 2.4 15.5 0.4 0.3 2.1 0.3 0.0 32.5 9.6 79.1 0.4 0.1 162.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 5.5 4.6 0.0 0.2 0.0 0.5 19.4 0.0 0.0 0.1 0.3 0.2 0.0 0.5 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.2 0.1 0.3 0.0 0.1 0.0 0.1 11.2 0.1 0.2 0.2 1799.0 4.5 0.1 0.0 0.1 1.0 0.7 1.8 0.1 0.0 4.2 0.0 0.2 0.6 1.9 0.4 0.2 0.3 0.5 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.5 0.1 0.0 3.1 0.3 1.2 0.6 0.6 0.2 0.0 0.3 0.1 0.2 0.0 0.3 0.4 0.0 942.3 84.5 0.0 2.3 0.0 4.9 17.9 0.0 0.0 3.5 2.0 0.2 75.8 322.1 0.0 0.0 0.0 0.0 640.1 0.0 77.0 0.2 0.4 0.1 1.3 5.4 0.0 0.1 16.3 0.0 1.3 1.5 0.8 7.0 0.0 0.4 0.3 0.0 0.0 0.1 102.3 14.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 156.7 391.1 0.0 0.0 24.2 5.7 0.0 71.8 0.0 0.0 0.0 9.9 0.0 0.1 15.6 0.0 0.0 1.2 0.0 31.7 182.3 CEACAM7 "CEA, CGM2" ENSG00000007306 "CEA cell adhesion molecule 7" Q14002 19 41673303-41706976 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 651.8" "Group enriched" "Detected in some" 9 "Distal enterocytes: 1454.0;Paneth cells: 731.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 66.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA069621, HPA073910" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "HPA069621: AB_2686162, HPA073910: " "unprognostic (5.24e-2)" "unprognostic (2.72e-1)" "unprognostic (1.64e-2)" "unprognostic (6.03e-2)" "unprognostic (2.07e-2)" "unprognostic (4.30e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.14e-1)" 0.6 0.0 0.0 71.4 0.0 0.1 2.9 0.0 0.0 13.3 0.0 595.8 0.5 0.3 0.0 52.6 0.6 39.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.4 651.8 0.0 4.0 0.8 0.1 1.4 0.7 5.7 0.0 0.2 2.0 0.1 0.0 0.0 0.0 0.0 12.0 23.4 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.2 0.9 0.0 0.0 0.1 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 1454.0 0.0 116.6 0.1 0.0 0.0 0.5 8.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 1.0 731.2 0.0 0.0 1.4 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 38.4 30.3 CEACAM8 "CD66b, CGM6" ENSG00000124469 "CEA cell adhesion molecule 8" P31997 19 42580243-42595055 "CD markers, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "bone marrow: 217.6" "Cell type enhanced" "Detected in single" "Paneth cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 1.6;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 6 "granulocytes: 1.6;monocytes: 1.2" "Not detected" "Not detected" CAB033676 Approved "Intracellular and membrane" NA NA 9200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "CAB033676: AB_1125678" "unprognostic (2.01e-1)" "unprognostic (4.52e-2)" "unprognostic (3.31e-1)" "unprognostic (6.30e-2)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" "unprognostic (1.71e-2)" "unprognostic (7.77e-2)" "unprognostic (9.62e-2)" 0.2 0.0 0.3 0.2 0.2 217.6 0.0 0.3 0.4 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.2 1.7 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.4 0.0 0.1 0.5 0.1 0.0 0.0 6.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.2 0.1 0.3 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 1.6 0.2 1.2 0.0 0.0 2.7 0.3 0.2 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 CEL "BSSL, MODY8" ENSG00000170835 "Carboxyl ester lipase" P19835 9 133061981-133071861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 548 "pancreas: 110578.0" "Group enriched" "Detected in many" 10 "Breast glandular cells: 390.7;Exocrine glandular cells: 943.6" "Cancer enriched" "Detected in many" 29 "pancreatic cancer: 469.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "JURKAT: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008023, HPA052701" Enhanced "Secreted to digestive system" NA NA 110000 "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA008023: AB_1846509, HPA052701: AB_2681921" "prognostic unfavorable (4.14e-4)" "unprognostic (2.30e-2)" "unprognostic (4.49e-2)" "unprognostic (3.14e-2)" "unprognostic (2.22e-1)" "unprognostic (2.48e-1)" "unprognostic (1.49e-1)" "unprognostic (6.27e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-2)" "unprognostic (2.51e-1)" "unprognostic (5.55e-2)" "unprognostic (2.26e-3)" "unprognostic (2.98e-1)" "unprognostic (4.41e-1)" "unprognostic (4.37e-2)" "unprognostic (1.02e-1)" 10.0 3.0 3.1 2.2 3.2 0.9 10.4 4.8 4.5 6.4 13.5 2.9 21.6 3.2 200.8 7.1 11.1 0.4 22.0 4.1 2.7 7.5 6.4 2.1 4.1 2.9 2.8 57.2 110578.0 0.3 201.7 7.1 3.0 5.1 1.3 1.1 19.9 3.3 2.2 5.5 9.2 0.5 2.5 3.4 18.5 2.5 3.0 1.9 2.5 0.4 0.6 3.4 3.4 3.0 0.3 0.8 3.1 1.9 1.0 0.7 3.1 0.6 0.3 0.4 0.6 0.9 0.6 0.9 1.5 0.6 0.5 2.2 0.7 5.9 0.2 1.9 1.2 1.6 0.5 2.1 0.4 0.7 5.9 1.5 3.8 0.5 0.3 1.3 0.6 7.5 1.0 0.8 0.5 1.3 0.9 3.2 5.2 0.7 1.0 1.8 0.9 0.7 0.4 2.7 5.3 1.3 0.7 0.7 0.3 4.5 1.0 2.9 0.4 1.5 2.0 1.7 0.4 0.4 3.4 0.7 0.0 1.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 3.2 4.8 4.5 4.1 2.7 2.9 2.8 3.0 2.5 3.0 3.0 1.5 0.0 0.0 1.0 0.7 0.0 1.7 0.8 1.2 1.0 390.7 4.4 2.1 1.5 0.5 0.0 0.0 0.1 1.8 2.5 3.9 1.7 0.5 62.4 0.8 0.9 0.0 0.0 2.0 943.6 0.1 0.4 0.0 1.3 0.0 4.7 0.0 0.1 0.0 0.0 1.4 0.8 26.4 0.0 0.3 3.6 0.3 1.0 0.0 0.0 6.7 0.9 0.0 1.0 0.7 27.7 0.1 0.0 0.0 0.4 10.6 0.1 2.3 0.8 0.0 0.2 1.4 0.2 0.1 2.0 0.3 0.4 0.5 6.0 5.1 3.0 CELA2A ELA2A ENSG00000142615 "Chymotrypsin like elastase 2A" P08217 1 15456728-15472091 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2325 "pancreas: 162732.5" "Cell type enriched" "Detected in some" 34 "Exocrine glandular cells: 7828.2" "Cancer enriched" "Detected in single" 3818 "pancreatic cancer: 463.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HMC-1: 1.2" "Secreted to digestive system" NA NA 2700000 "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (9.78e-2)" "unprognostic (3.33e-2)" "unprognostic (5.60e-2)" "unprognostic (5.27e-2)" "unprognostic (3.63e-3)" "unprognostic (2.35e-1)" "unprognostic (4.14e-1)" "unprognostic (1.96e-2)" "unprognostic (1.38e-1)" "unprognostic (2.48e-1)" "unprognostic (3.94e-9)" "unprognostic (4.10e-2)" "unprognostic (3.42e-1)" "unprognostic (3.55e-2)" 7.9 5.5 0.0 2.6 0.0 1.1 4.4 0.2 0.1 3.9 0.0 2.0 18.5 2.1 0.0 2.3 1.1 0.0 26.9 0.0 0.0 1.6 5.8 1.2 4.3 0.0 0.0 70.0 162732.5 0.0 1.3 10.2 0.0 2.7 0.0 0.0 28.0 0.0 1.6 2.2 8.7 0.0 0.0 2.2 15.4 2.0 0.0 0.0 1.1 0.0 0.0 0.9 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.8 0.1 0.3 0.3 0.3 0.0 0.0 1.1 7828.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 20.7 0.0 0.0 0.0 0.1 227.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 CELA2B "ELA2B, RP11-265F14.2" ENSG00000215704 "Chymotrypsin like elastase 2B" P08218 1 15465909-15491395 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1672 "pancreas: 20446.9" "Cell type enriched" "Detected in some" 73 "Exocrine glandular cells: 1227.6" "Cancer enriched" "Detected in single" 574 "pancreatic cancer: 69.9" "Group enriched" "Detected in some" 4 "cerebellum: 2.0;cerebral cortex: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "U-138 MG: 3.9" "Secreted to digestive system" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 25: Pancreas - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (4.36e-3)" "unprognostic (5.45e-2)" "unprognostic (6.66e-2)" "unprognostic (5.31e-3)" "unprognostic (4.47e-3)" "unprognostic (1.37e-3)" "unprognostic (4.66e-2)" "unprognostic (6.32e-2)" "unprognostic (2.73e-1)" "unprognostic (2.44e-1)" "unprognostic (2.94e-1)" "unprognostic (3.85e-2)" "unprognostic (1.22e-6)" "unprognostic (2.47e-1)" "unprognostic (6.67e-2)" "unprognostic (1.88e-1)" "unprognostic (7.80e-2)" 1.1 3.0 0.0 0.5 0.0 1.0 0.6 2.0 3.2 0.4 0.0 0.2 3.7 0.4 0.1 0.3 0.1 0.6 4.5 0.3 0.6 0.2 0.6 0.3 1.2 0.2 0.2 12.2 20446.9 0.0 0.1 1.2 0.0 0.3 0.0 1.7 3.4 0.0 0.3 1.0 2.4 0.0 0.0 0.3 1.2 0.7 0.4 0.0 0.8 0.0 0.0 0.1 0.1 0.3 0.0 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.5 0.8 0.4 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 3.2 0.3 0.6 0.2 0.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 1.4 1227.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.1 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 CELA3A "ELA3, ELA3A" ENSG00000142789 "Chymotrypsin like elastase 3A" P09093 1 22001657-22012542 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2216 "pancreas: 262614.2" "Cell type enriched" "Detected in some" 56 "Exocrine glandular cells: 34710.4" "Cancer enriched" "Detected in some" 2497 "pancreatic cancer: 1481.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 28 "MOLT-4: 24.9" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA028086: AB_2672482, HPA045650: AB_2679407" "unprognostic (1.27e-1)" "unprognostic (2.71e-1)" "unprognostic (1.79e-1)" "unprognostic (6.32e-2)" "unprognostic (2.67e-1)" 20.0 4.5 0.0 3.0 0.0 2.8 11.6 0.0 0.0 12.9 0.0 4.5 21.3 4.1 0.0 7.4 3.0 0.1 44.6 0.0 0.0 4.1 13.5 3.0 6.0 0.0 0.0 118.5 262614.2 0.0 6.9 14.9 0.0 8.8 0.0 0.0 44.0 0.0 3.9 5.2 12.2 0.0 0.0 6.3 47.7 3.2 0.0 0.3 3.1 0.0 0.0 2.9 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 25.5 40.7 0.1 0.0 0.6 0.0 0.0 0.1 34710.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 197.1 0.3 2.4 0.0 0.0 94.0 0.0 0.0 0.0 0.0 619.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.8 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CELA3B "CBPP, ELA3B" ENSG00000219073 "Chymotrypsin like elastase 3B" P08861 1 21977022-21998642 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2088 "pancreas: 49621.1" "Cell type enriched" "Detected in some" 45 "Exocrine glandular cells: 14881.1" "Cancer enriched" "Detected in single" 1218 "pancreatic cancer: 408.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA028086: AB_2672482, HPA045650: AB_2679407" "unprognostic (2.89e-1)" "unprognostic (4.01e-3)" "unprognostic (6.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (6.40e-2)" 9.0 1.8 0.0 0.6 0.0 0.8 4.5 0.0 0.0 4.4 0.0 1.8 6.2 1.6 0.1 2.6 1.2 0.0 8.4 0.0 0.0 1.6 5.0 1.2 1.1 0.0 0.0 23.7 49621.1 0.0 2.2 3.4 0.0 3.1 0.1 0.0 9.5 0.0 1.6 1.9 2.6 0.0 0.0 2.3 17.2 2.4 0.0 0.0 1.2 0.0 0.0 1.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 10.4 78.6 0.3 0.0 0.6 0.0 0.0 0.2 14881.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 309.9 0.9 0.9 0.0 0.0 60.4 0.0 0.0 0.0 0.2 325.6 16.0 0.7 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 CELF4 BRUNOL4 ENSG00000101489 "CUGBP Elav-like family member 4" Q9BZC1 18 37243040-37565827 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 122.2" "Group enriched" "Detected in many" 4 "Bipolar cells: 126.4;Excitatory neurons: 197.7;Horizontal cells: 294.4;Inhibitory neurons: 197.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "SCLC-21H: 46.7;SH-SY5Y: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013322, HPA037986" Enhanced Supported Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA013322: , HPA037986: AB_10673035" "unprognostic (7.87e-3)" "unprognostic (2.31e-2)" "unprognostic (4.31e-3)" "unprognostic (3.42e-7)" "unprognostic (2.95e-2)" "unprognostic (2.95e-2)" "unprognostic (3.72e-3)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.92e-2)" "unprognostic (1.00e-2)" "unprognostic (3.49e-1)" "unprognostic (1.69e-2)" "unprognostic (2.48e-1)" "unprognostic (8.32e-3)" "unprognostic (6.13e-2)" 0.6 11.5 102.9 1.1 104.8 0.3 0.4 59.5 122.2 0.3 11.1 1.9 0.8 0.4 0.6 0.5 0.4 1.2 1.0 96.4 81.2 1.5 0.3 0.6 0.8 58.3 69.7 1.3 3.9 0.3 28.4 0.8 71.4 0.8 0.4 21.4 1.7 0.2 11.0 1.3 1.2 0.5 34.6 1.1 1.7 3.6 57.4 0.0 1.5 0.2 0.1 0.2 0.5 94.4 0.1 0.1 0.7 0.6 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.5 0.3 1.0 0.0 0.2 0.6 0.1 0.0 0.0 0.8 0.4 0.0 1.8 0.4 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.8 0.0 0.3 0.1 0.5 1.7 0.0 0.3 0.1 0.0 2.1 0.0 0.1 46.7 11.7 1.1 0.3 0.1 0.3 0.2 0.1 0.0 1.4 0.7 0.3 0.2 2.9 0.5 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.9 104.8 59.5 122.2 96.4 81.2 58.3 69.7 71.4 34.6 57.4 94.4 0.2 0.0 0.0 22.5 0.8 0.4 1.4 0.9 0.0 126.4 0.4 0.5 1.9 0.0 0.3 0.0 41.7 0.3 0.1 0.2 0.0 0.4 46.9 0.7 0.9 4.1 12.7 0.0 197.7 1.1 0.3 1.2 2.0 1.2 0.0 1.8 0.7 0.0 8.6 294.4 197.5 2.5 6.1 0.0 0.0 22.6 0.6 0.3 0.0 14.0 0.0 7.3 0.0 19.1 12.3 2.6 0.2 5.3 0.0 2.7 4.4 6.7 0.3 22.0 0.0 4.3 8.2 12.6 7.6 0.0 0.6 0.3 0.3 1.5 3.5 1.2 CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 31.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Basal respiratory cells: 28.1;Club cells: 31.1;Endometrial ciliated cells: 31.8;Glandular and luminal cells: 42.6;Respiratory ciliated cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Cell line enhanced" "Detected in many" "A549: 68.4;RPTEC TERT1: 48.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 280000 "Cluster 43: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA052976: AB_2682004, HPA060521: AB_2684303" "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" 0.7 0.8 0.4 3.1 0.9 0.8 7.8 1.5 0.5 9.9 1.2 1.6 0.9 3.7 10.2 11.5 15.4 1.4 3.4 1.0 0.4 17.1 5.2 12.5 5.9 2.4 3.9 0.2 2.6 6.3 2.4 1.0 1.4 5.0 1.8 0.5 12.0 3.9 0.2 31.5 1.6 1.1 1.6 3.3 5.4 1.3 2.2 2.4 3.7 0.1 7.9 3.9 3.7 1.0 22.3 68.4 11.3 10.6 0.0 0.0 6.5 2.3 3.4 2.3 1.3 21.7 21.9 0.2 32.1 1.3 22.0 35.0 7.5 28.7 2.0 0.0 10.2 0.0 25.6 2.0 1.0 3.2 1.8 0.0 43.5 0.0 26.2 31.6 0.4 1.7 0.3 0.4 0.0 38.4 0.1 11.9 4.5 12.1 8.1 0.1 0.1 8.1 48.7 13.5 0.7 0.9 16.1 17.3 3.7 7.9 39.7 16.7 0.9 0.1 0.3 0.0 0.4 10.6 1.1 10.5 15.2 0.1 12.9 0.0 0.0 0.0 0.2 0.1 0.2 2.2 0.1 0.1 0.0 1.9 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.4 0.9 1.5 0.5 1.0 0.4 2.4 3.9 1.4 1.6 2.2 1.0 0.5 41.7 23.5 0.0 5.8 17.1 4.1 28.1 8.0 0.2 14.2 5.2 12.7 2.8 31.1 5.5 0.0 1.9 2.3 0.8 0.0 1.8 2.3 31.8 5.0 5.6 1.2 0.0 1.2 0.7 1.9 1.0 2.6 42.6 0.0 0.6 1.8 1.5 2.4 0.0 1.2 2.8 6.1 0.0 4.1 10.3 0.0 1.1 5.4 1.0 1.1 1.1 0.0 0.5 0.7 4.0 0.3 0.0 1.1 4.3 0.0 8.2 60.3 0.3 0.0 0.1 2.8 0.4 0.6 12.6 15.6 0.8 1.1 0.0 1.7 5.1 CEMIP "HYBID, IR2155535, KIAA1199, TMEM2L" ENSG00000103888 "Cell migration inducing hyaluronidase 1" Q8WUJ3 15 80779343-80951776 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 25.3;endometrium 1: 31.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 62.5;Inhibitory neurons: 40.0;Microglial cells: 101.2" "Cancer enhanced" "Detected in all" "colorectal cancer: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 204.1;BJ hTERT+: 321.8;fHDF/TERT166: 258.7;HSkMC: 169.3;hTERT-RPE1: 187.6;U-138 MG: 90.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 1700000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.14e-3)" "unprognostic (6.80e-2)" "unprognostic (5.95e-2)" "unprognostic (3.15e-3)" "unprognostic (3.49e-3)" "unprognostic (6.80e-2)" "unprognostic (5.47e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (1.53e-1)" "unprognostic (7.24e-2)" "unprognostic (1.36e-1)" "unprognostic (5.27e-10)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.65e-4)" 5.7 1.7 1.6 11.2 8.8 1.5 0.8 5.5 11.1 13.3 25.3 1.3 0.8 31.9 6.9 6.4 6.2 2.1 1.9 2.4 3.5 0.9 0.8 15.0 9.5 3.0 1.7 4.7 1.0 1.5 8.0 2.6 2.4 2.0 1.8 4.1 1.9 1.6 0.4 5.9 1.6 0.6 5.1 1.8 0.9 2.9 4.4 0.3 3.9 0.0 4.7 14.0 2.6 3.1 0.7 7.7 1.5 1.1 0.5 2.8 0.9 204.1 321.8 5.4 4.1 2.4 1.0 1.0 0.6 258.7 0.9 4.9 0.0 0.7 1.1 0.6 1.9 0.7 1.3 17.1 1.9 0.5 1.0 169.3 0.2 39.6 0.2 187.6 0.0 1.0 1.0 0.8 4.8 4.7 0.7 0.5 1.0 68.9 9.2 1.2 0.3 0.9 0.0 3.5 12.7 0.4 3.5 0.5 17.7 2.7 1.0 0.4 1.0 90.6 0.9 6.8 3.5 0.8 0.7 1.2 9.6 1.8 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.6 8.8 5.5 11.1 2.4 3.5 3.0 1.7 2.4 5.1 4.4 3.1 0.1 0.0 1.5 2.9 0.1 0.0 0.3 0.0 11.4 2.9 0.0 0.1 1.2 0.0 4.3 0.0 6.2 0.2 0.0 1.1 0.0 0.1 1.0 0.7 4.3 1.6 4.8 0.0 62.5 0.4 0.2 4.3 0.0 7.0 1.3 0.1 0.4 0.0 0.4 3.3 40.0 0.5 0.0 0.0 0.0 0.6 0.3 0.9 0.0 101.2 0.0 0.4 0.0 6.6 8.2 0.7 0.1 0.0 0.1 2.7 0.0 0.1 0.0 3.0 0.0 0.4 0.8 0.2 0.7 1.0 0.0 0.3 0.1 0.1 0.8 0.9 CENPM "C22orf18, CENP-M, MGC861, Pane1" ENSG00000100162 "Centromere protein M" Q9NSP4 22 41938737-41947152 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.0;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 116.7;Erythroid cells: 60.0;Plasma cells: 70.8;Respiratory ciliated cells: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 50.8" "Group enriched" "Detected in many" 6 "B-cells: 38.6;T-cells: 50.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042404 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "HPA042404: AB_2677981" "unprognostic (3.78e-2)" "prognostic favorable (3.40e-5)" "unprognostic (7.15e-3)" "unprognostic (2.65e-3)" "unprognostic (2.02e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (5.50e-5)" "unprognostic (1.46e-2)" "unprognostic (1.20e-1)" "unprognostic (2.74e-1)" "unprognostic (1.63e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (5.99e-7)" "unprognostic (9.54e-3)" "unprognostic (2.44e-1)" "unprognostic (8.73e-2)" "unprognostic (5.61e-2)" 1.3 1.5 0.6 9.9 0.6 29.0 1.9 1.8 1.1 2.3 0.3 9.9 8.4 1.7 0.1 9.9 10.8 2.0 0.7 0.5 0.7 2.3 1.6 3.8 25.1 0.8 0.8 0.7 0.7 0.3 0.5 3.2 0.8 1.4 5.3 0.1 3.6 0.3 0.9 8.0 8.3 1.8 0.5 10.6 6.1 12.8 1.0 22.6 0.8 0.4 16.3 2.0 4.0 0.5 79.1 79.0 43.5 28.8 3.3 3.3 18.4 37.8 19.4 65.2 66.2 92.3 41.0 101.5 27.8 20.2 42.2 29.5 32.9 38.8 16.2 29.4 137.4 47.8 82.3 64.9 3.2 91.4 51.9 2.7 2.9 42.1 19.3 6.9 24.8 91.5 36.7 95.0 38.8 121.9 91.9 94.8 23.6 47.5 58.1 86.8 43.4 105.6 26.9 46.5 49.3 9.4 58.5 34.5 20.6 7.2 32.8 58.4 12.5 62.8 93.4 42.0 64.1 50.5 38.0 95.2 21.9 75.9 70.0 1.8 0.3 0.0 6.2 0.2 8.8 27.9 18.6 8.4 0.7 38.6 3.5 4.6 1.1 7.4 0.2 0.4 50.8 7.9 0.6 0.6 1.8 1.1 0.5 0.7 0.8 0.8 0.8 0.5 1.0 0.5 0.4 0.0 3.4 0.3 50.7 2.0 4.8 17.8 1.8 1.9 10.9 10.3 0.6 0.0 7.9 0.0 0.0 39.7 5.4 25.3 17.6 2.1 4.5 116.7 4.2 2.6 7.7 60.0 0.5 0.7 38.9 6.4 10.7 18.0 2.5 15.8 3.6 1.3 43.4 3.3 0.8 34.5 28.5 2.9 3.5 6.7 1.2 5.4 7.2 1.0 1.8 0.1 2.1 1.0 0.2 1.5 8.4 0.4 70.8 2.8 4.0 0.3 102.6 0.6 0.0 0.2 7.0 36.4 29.8 13.3 1.0 8.8 18.5 2.9 36.6 9.0 CEP192 "FLJ10352, KIAA1569, PPP1R62" ENSG00000101639 "Centrosomal protein 192" Q8TEP8 18 12991362-13125052 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 67.6;Excitatory neurons: 94.4;Inhibitory neurons: 91.3;Oligodendrocyte precursor cells: 76.9;Oligodendrocytes: 90.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039392, HPA040503" Uncertain Supported Centrosome,Cytosol Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Centrosome, Cytosol" "HPA039392: AB_10697549, HPA040503: AB_10670919" "unprognostic (6.94e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (5.89e-2)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (1.13e-3)" "unprognostic (6.87e-3)" "unprognostic (5.83e-3)" "unprognostic (2.20e-2)" "unprognostic (9.00e-2)" "unprognostic (6.61e-2)" "unprognostic (1.28e-1)" "unprognostic (7.89e-2)" "unprognostic (2.39e-1)" "unprognostic (4.54e-2)" "unprognostic (1.66e-3)" 2.9 2.2 5.0 4.6 7.6 10.8 4.9 9.8 5.2 4.7 0.0 4.5 4.0 6.4 3.9 3.7 4.9 5.7 3.6 4.1 2.4 2.8 2.9 4.4 6.9 4.1 4.7 9.9 4.6 4.7 2.5 4.6 3.6 4.0 5.4 6.8 4.1 3.5 1.8 3.5 4.7 4.6 3.4 5.2 4.7 9.3 5.0 11.6 5.5 3.9 5.6 4.1 2.5 9.7 13.5 7.2 19.1 10.1 8.1 12.6 6.1 9.2 12.1 14.3 15.1 9.9 5.8 15.2 6.1 9.4 10.4 6.4 16.7 8.8 16.8 6.0 6.0 13.8 11.3 5.2 4.3 22.2 10.2 8.8 3.2 12.0 10.9 8.2 11.9 10.7 19.3 9.9 11.3 6.8 19.2 9.6 6.1 24.9 4.4 16.3 14.9 7.9 4.9 13.6 13.9 7.8 14.7 7.2 4.4 9.0 5.8 11.3 12.1 11.2 26.2 12.9 12.8 6.6 10.1 17.0 7.2 9.9 11.0 0.4 0.6 0.5 0.9 0.4 0.7 0.5 0.6 0.6 0.3 1.3 0.6 1.0 0.6 0.2 1.7 0.5 0.5 0.3 5.0 7.6 9.8 5.2 4.1 2.4 4.1 4.7 3.6 3.4 5.0 9.7 13.3 9.6 12.8 67.6 11.4 1.9 3.9 4.3 5.2 13.1 6.4 5.8 28.7 4.3 9.3 7.3 22.9 5.3 13.7 7.6 0.0 4.7 23.3 11.0 11.8 8.5 0.0 18.7 94.4 3.6 3.3 10.5 15.8 12.1 2.5 40.9 8.2 6.5 4.6 11.8 91.3 8.7 4.1 10.1 3.9 14.2 10.2 10.1 1.8 62.8 15.3 6.5 14.4 76.9 90.6 4.8 5.7 13.9 15.0 5.5 4.5 1.2 8.0 17.8 26.3 11.3 8.1 33.5 24.0 8.5 3.1 1.9 12.3 60.6 8.0 7.6 CEP41 "DKFZp762H1311, FLJ22445, JBTS15, TSGA14" ENSG00000106477 "Centrosomal protein 41" Q9BYV8 7 130393771-130442433 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Autism, Autism spectrum disorder, Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.0" "Cell type enhanced" "Detected in all" "Early spermatids: 526.8;Late spermatids: 160.6;Spermatocytes: 96.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024090 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA024090: AB_10966276" "unprognostic (3.87e-2)" "unprognostic (5.96e-2)" "prognostic favorable (4.54e-4)" "unprognostic (1.17e-3)" "unprognostic (2.88e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-7)" "unprognostic (1.80e-1)" "unprognostic (2.89e-1)" "unprognostic (8.45e-3)" "unprognostic (4.63e-2)" "unprognostic (1.37e-1)" "unprognostic (7.76e-2)" "unprognostic (7.72e-2)" "unprognostic (3.35e-2)" "unprognostic (9.87e-2)" "unprognostic (1.57e-1)" 3.8 5.2 4.9 3.5 5.0 4.2 3.6 3.6 5.6 3.5 8.8 3.0 3.2 4.3 3.7 2.6 9.4 4.6 2.0 5.3 5.2 3.3 2.7 3.2 4.7 4.8 8.1 3.5 2.2 5.1 4.7 4.5 5.2 3.2 3.6 7.7 17.8 3.6 1.6 2.4 2.2 5.3 4.7 4.2 2.8 47.0 5.3 8.6 4.1 2.3 4.9 3.2 1.4 6.4 15.9 16.5 17.6 11.4 5.1 8.9 3.6 21.0 10.4 12.4 13.9 9.8 19.3 23.1 11.3 12.3 34.4 15.2 17.6 11.3 17.2 8.0 5.0 8.4 7.2 5.2 8.5 16.7 8.0 9.7 8.6 16.2 7.2 12.0 21.9 16.7 4.8 5.3 21.5 10.7 43.2 14.7 15.7 17.4 12.6 30.3 25.7 0.7 9.1 10.3 25.4 21.0 14.0 19.9 16.3 9.9 6.1 12.8 11.0 18.4 7.2 17.6 27.3 12.2 39.9 28.8 20.7 16.4 27.8 7.9 4.6 5.9 7.5 6.9 4.9 3.6 5.4 5.7 8.3 4.5 8.4 13.9 0.8 11.2 3.3 4.0 6.3 7.4 4.9 5.0 3.6 5.6 5.3 5.2 4.8 8.1 5.2 4.7 5.3 6.4 8.7 9.6 4.1 7.2 5.0 1.8 6.4 13.5 4.6 18.1 11.6 9.0 4.4 4.3 10.1 9.2 37.5 16.2 3.8 3.1 11.7 12.9 526.8 35.9 8.9 9.6 14.4 12.4 14.5 9.2 10.9 7.8 4.6 5.3 11.4 13.3 12.8 3.4 18.7 15.2 12.5 4.7 10.2 8.9 2.2 160.6 10.5 8.0 5.4 5.6 4.0 10.2 9.2 17.1 14.2 7.0 3.7 8.2 1.9 4.0 2.0 5.2 55.5 22.0 6.6 6.3 7.4 96.0 35.0 4.1 1.6 19.2 5.8 8.7 6.3 6.5 CEP57 "KIAA0092, Translokin, TSP57" ENSG00000166037 "Centrosomal protein 57" Q86XR8 11 95789965-95832693 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 462.9;Late spermatids: 372.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA018315 Approved Approved Microtubules,Cytosol "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 34: Spermatids - Unknown function" Microtubules Cytosol "HPA018315: AB_1846537" "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (1.45e-2)" "unprognostic (2.66e-1)" "prognostic favorable (7.24e-4)" "unprognostic (1.69e-1)" "unprognostic (2.25e-2)" "unprognostic (8.10e-2)" "unprognostic (9.04e-3)" "unprognostic (7.93e-2)" "unprognostic (2.38e-3)" "unprognostic (7.81e-2)" "unprognostic (1.06e-1)" "unprognostic (4.31e-2)" "unprognostic (1.35e-1)" "unprognostic (6.69e-3)" "unprognostic (3.25e-1)" 16.6 14.0 10.6 19.2 11.4 29.0 21.6 15.0 13.3 19.0 12.6 17.7 32.4 21.8 19.8 15.0 17.7 27.3 15.6 10.4 11.2 15.7 44.6 16.9 30.1 12.2 11.2 31.2 22.8 12.2 14.9 16.1 10.8 16.2 18.6 25.9 14.1 17.3 12.8 17.8 21.9 15.5 10.9 20.5 17.8 27.9 11.7 34.2 22.7 14.3 30.6 14.0 15.1 12.4 26.7 13.1 42.0 32.7 19.4 38.6 34.4 29.8 48.6 41.4 46.1 47.5 55.1 47.1 39.6 22.4 24.2 43.8 34.7 29.5 43.8 38.1 21.8 66.4 36.9 38.4 33.9 67.0 37.2 25.9 42.5 43.2 80.4 39.3 33.4 49.6 43.8 25.3 33.8 13.1 74.7 89.1 23.3 30.2 29.2 43.8 53.2 40.7 34.8 27.8 21.5 28.9 36.1 34.4 38.3 29.7 35.1 44.0 17.2 35.2 28.3 52.0 28.2 16.9 38.1 51.7 14.6 74.4 31.0 19.0 11.8 24.3 19.5 14.4 25.9 23.6 25.7 22.7 15.6 21.7 24.8 23.5 11.6 26.0 13.2 21.1 33.7 17.5 10.6 11.4 15.0 13.3 10.4 11.2 12.2 11.2 10.8 10.9 11.7 12.4 43.7 54.5 51.1 35.9 58.5 36.3 30.6 35.7 51.2 72.3 30.6 42.7 41.3 85.8 41.7 29.5 35.5 44.1 42.8 16.2 54.8 34.2 462.9 52.2 33.0 38.2 28.8 88.1 68.0 25.7 50.8 41.1 18.3 33.0 27.3 58.4 30.7 71.5 33.1 57.2 78.3 34.0 16.2 35.0 37.3 372.7 33.8 33.2 17.8 27.2 37.6 29.6 44.3 57.8 60.9 26.2 23.9 35.7 57.8 28.8 45.2 40.2 52.6 59.0 65.7 34.4 37.8 75.8 46.1 42.0 32.0 38.4 59.1 53.0 47.2 27.6 CEP89 "CCDC123, FLJ14640" ENSG00000121289 "Centrosomal protein 89" Q96ST8 19 32875925-32971991 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039382, HPA040056" Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane" "HPA039382: AB_2676479, HPA040056: AB_10671048" "unprognostic (4.23e-2)" "unprognostic (7.50e-3)" "unprognostic (1.97e-1)" "unprognostic (1.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.78e-5)" "unprognostic (1.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.04e-2)" "unprognostic (1.80e-2)" "unprognostic (4.00e-2)" "unprognostic (1.74e-1)" "unprognostic (4.48e-2)" "unprognostic (6.53e-2)" "unprognostic (3.03e-1)" "unprognostic (2.47e-2)" 6.0 6.0 6.3 5.3 6.7 4.7 6.4 7.7 6.4 9.1 7.7 8.9 4.0 9.8 6.7 6.3 8.9 5.1 6.2 6.6 6.9 8.6 3.3 5.7 6.0 5.8 5.6 10.1 6.1 7.0 9.3 5.3 4.7 12.5 4.4 7.4 6.7 5.9 5.9 6.6 6.7 6.9 4.0 6.4 6.2 4.2 7.3 6.2 7.5 4.3 4.3 8.0 6.8 6.0 19.1 25.7 17.1 14.7 9.1 11.0 9.9 14.7 9.8 25.5 19.4 9.3 11.2 7.6 7.8 15.1 14.4 10.5 16.9 11.9 17.6 20.2 10.4 5.9 18.5 8.9 7.2 8.3 5.7 13.3 16.2 24.1 16.2 10.4 19.5 10.4 9.2 11.0 12.3 14.2 9.4 6.4 7.3 10.4 8.0 10.4 9.2 6.6 11.9 10.3 24.1 17.7 15.1 10.3 8.8 10.3 7.7 6.7 12.6 18.4 16.1 16.0 15.3 5.3 9.1 7.0 15.8 7.8 14.0 12.8 3.1 1.6 2.7 4.6 4.9 3.3 2.9 2.4 1.8 5.7 2.8 3.3 3.7 2.1 2.4 3.7 3.4 1.7 6.3 6.7 7.7 6.4 6.6 6.9 5.8 5.6 4.7 4.0 7.3 6.0 12.7 28.9 16.0 17.3 9.5 5.1 11.5 14.5 8.0 16.3 11.7 11.8 17.5 10.0 19.0 20.2 18.8 9.3 9.6 8.0 11.7 19.1 15.1 49.2 24.9 14.8 9.7 13.3 17.2 16.6 11.2 17.7 10.7 17.3 17.1 21.1 14.6 5.6 11.8 20.2 13.6 9.7 8.2 5.3 5.1 8.5 16.1 8.9 5.4 14.0 9.8 9.6 10.3 9.5 15.9 15.1 5.2 12.8 5.4 6.7 9.9 16.3 48.3 38.6 0.0 17.5 16.1 20.3 13.8 7.5 4.5 4.2 9.0 12.7 8.6 6.6 CER1 DAND4 ENSG00000147869 "Cerberus 1, DAN family BMP antagonist" O95813 9 14719724-14722733 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "epididymis: 1.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 82 "testis cancer: 17.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEL: 4.0;NTERA-2: 7.0;SCLC-21H: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA019917 Uncertain "Secreted - unknown location" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 50: Fibroblasts - ECM organization" "HPA019917: AB_1846539" "unprognostic (2.98e-2)" "unprognostic (5.36e-2)" "unprognostic (5.99e-2)" 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.1 0.3 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Metabolic proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 551.5" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 626.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 280.5;ASC TERT1: 284.1;fHDF/TERT166: 271.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" 26.1 8.9 249.9 12.3 411.3 2.5 24.5 248.6 378.3 42.4 140.1 20.9 7.9 35.0 9.7 13.1 23.4 31.2 34.0 261.5 322.7 25.9 3.7 16.9 4.1 344.1 349.4 31.2 30.1 31.0 106.4 49.4 323.9 27.9 7.7 1.0 21.4 22.8 7.0 15.0 12.3 47.4 224.7 10.9 15.8 11.1 386.4 2.4 23.4 7.0 3.9 29.9 30.8 551.5 44.7 26.0 35.2 38.2 280.5 284.1 27.4 145.5 149.7 41.2 32.0 10.3 2.4 0.0 58.3 271.9 33.5 33.8 14.7 22.2 13.9 11.7 25.6 2.9 24.1 15.5 89.7 5.4 84.4 171.6 11.7 48.4 10.5 157.7 44.3 3.0 13.0 36.5 51.8 82.3 2.3 55.7 1.8 2.3 25.4 4.7 23.6 7.3 18.4 15.5 4.9 8.5 33.8 43.1 16.7 10.1 34.4 13.7 48.2 103.5 27.3 138.1 23.2 42.2 35.0 0.8 99.7 17.1 21.0 0.1 0.6 0.0 1.8 0.7 0.1 0.1 0.1 2.1 0.7 0.0 0.0 2.3 0.0 0.6 0.0 1.0 0.0 1.3 249.9 411.3 248.6 378.3 261.5 322.7 344.1 349.4 323.9 224.7 386.4 551.5 8.5 6.4 10.3 7.2 3.5 8.9 6.5 7.0 10.8 1.7 8.7 6.9 3.9 0.0 13.6 11.0 0.0 18.4 5.8 0.0 0.0 11.6 2.7 3.1 18.7 7.7 0.0 2.5 2.9 3.4 61.1 82.3 3.6 6.7 8.8 9.8 16.8 0.1 6.2 6.7 3.3 0.0 2.0 0.8 10.4 2.3 24.2 2.9 40.9 3.7 1.3 0.1 17.5 11.6 626.9 4.5 0.0 26.4 17.9 5.0 0.0 0.9 3.9 0.9 6.6 27.8 26.4 8.6 22.2 2.4 4.1 19.6 3.3 5.9 0.0 2.8 CERT1 "CERT, COL4A3BP, GPBP, STARD11" ENSG00000113163 "Ceramide transporter 1" Q9Y5P4 5 75356345-75512138 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 23.3;Cardiomyocytes: 37.1;Cytotrophoblasts: 17.7;dendritic cells: 20.2;Extravillous trophoblasts: 16.8;Hofbauer cells: 36.8;Plasma cells: 12.4;Syncytiotrophoblasts: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 132.3;WM-115: 118.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035645, HPA042608" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" Nucleoplasm "HPA035645: AB_10600700, HPA042608: AB_2678075" "unprognostic (2.45e-1)" "unprognostic (7.16e-2)" "unprognostic (6.56e-3)" "unprognostic (1.53e-2)" "unprognostic (2.44e-1)" "unprognostic (9.29e-2)" "unprognostic (4.06e-2)" "unprognostic (3.22e-1)" "unprognostic (2.51e-1)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "unprognostic (4.29e-2)" "prognostic favorable (1.24e-5)" "unprognostic (9.12e-2)" "unprognostic (2.29e-1)" "unprognostic (2.83e-1)" "unprognostic (2.91e-1)" 38.1 26.1 12.4 16.5 16.1 27.2 17.6 18.0 15.4 33.9 14.0 20.8 18.7 20.6 15.1 24.9 22.4 23.3 20.8 14.0 15.1 27.9 31.2 24.3 20.3 14.7 17.5 23.1 16.4 26.1 8.0 22.9 16.7 24.3 19.6 18.2 14.0 19.9 28.9 18.7 21.1 18.3 14.7 25.3 23.5 28.8 15.5 21.2 49.9 28.3 22.7 23.7 16.0 17.6 44.9 22.7 21.6 19.0 132.3 36.6 29.0 24.8 30.8 18.8 24.8 34.4 25.3 21.5 52.3 26.9 25.8 26.7 33.4 34.4 28.6 27.1 15.2 18.2 24.4 18.4 33.6 18.2 20.1 27.9 23.8 22.3 24.9 30.5 22.1 28.3 33.0 32.0 25.0 23.0 21.6 13.2 27.9 10.2 16.8 18.0 28.5 20.2 30.5 54.0 16.4 16.5 31.6 21.6 31.8 45.4 21.3 30.5 30.1 12.6 15.1 22.8 20.3 29.1 41.6 24.8 21.4 30.7 118.2 9.6 19.8 16.0 8.2 22.4 7.8 9.1 8.3 7.7 14.5 9.1 7.7 7.8 29.6 7.8 25.4 8.3 13.0 9.0 12.4 16.1 18.0 15.4 14.0 15.1 14.7 17.5 16.7 14.7 15.5 17.6 23.3 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 0.0 0.0 0.0 0.0 17.7 20.2 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 16.8 10.5 0.0 0.0 0.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 27.8 3.8 0.0 0.0 0.0 CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 2517.1" "Group enriched" "Detected in many" 7 "Cholangiocytes: 613.4;Hepatocytes: 2420.8" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 16 "classical monocyte: 109.6;myeloid DC: 114.5" "Group enriched" "Detected in many" 22 "dendritic cells: 114.5;monocytes: 109.6" "Group enriched" "Detected in some" 5 "Hep G2: 700.9;THP-1: 688.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No NA 40000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavorable (9.92e-4)" 94.9 14.1 0.9 3.2 1.2 27.0 43.6 0.8 1.8 26.6 3.7 82.3 24.0 60.4 7.5 41.1 54.6 272.9 66.1 1.0 1.4 6.7 2517.1 167.8 1.8 2.3 1.2 20.3 8.8 0.7 3.7 8.5 1.5 39.2 12.3 2.9 41.4 36.4 5.2 14.0 27.4 40.4 1.0 41.0 56.1 7.8 1.1 2.5 9.9 9.4 1.0 57.7 17.7 1.1 0.7 4.4 0.0 0.0 90.8 0.6 3.1 0.3 0.0 0.0 0.0 43.5 0.0 0.0 19.4 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.9 700.9 0.0 1.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 40.8 0.1 0.6 0.0 0.0 1.5 6.7 0.0 0.5 0.0 0.1 3.2 0.1 1.1 0.9 0.0 688.0 0.1 0.0 0.4 0.2 0.5 2.2 0.1 1.0 0.0 151.7 0.0 0.0 109.6 0.5 4.5 6.1 1.5 1.1 0.7 5.0 114.5 1.2 0.7 1.1 0.6 0.3 1.6 6.8 0.4 58.0 0.9 1.2 0.8 1.8 1.0 1.4 2.3 1.2 1.5 1.0 1.1 1.1 2.0 16.0 67.6 0.0 11.3 16.7 5.3 6.8 1.2 0.0 1.2 8.1 0.8 613.4 31.5 16.5 0.0 0.5 12.2 0.1 0.0 15.4 79.6 1.0 10.6 8.9 37.5 177.7 0.0 18.7 2.2 57.4 1.1 0.2 6.3 0.0 66.0 2420.8 18.1 0.0 0.0 12.2 4.1 107.3 26.7 197.8 18.6 58.7 39.2 1.0 39.6 10.4 7.2 0.0 0.0 0.9 1.3 98.9 1.8 1.5 0.6 0.9 169.0 0.9 0.0 9.8 9.8 1.0 2.3 20.6 11.6 0.8 16.9 0.9 0.7 2.6 CES2 "CE-2, CES2A1, iCE" ENSG00000172831 "Carboxylesterase 2" O00748 16 66934444-66945096 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 703.3;liver: 345.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 794.4;Hepatocytes: 518.5;Paneth cells: 519.2;Proximal enterocytes: 2529.8;Undifferentiated cells: 499.5" "Cancer enhanced" "Detected in all" "liver cancer: 104.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "HPA018897, HPA074629" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 6400000 "Cluster 44: Non-specific - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "Endoplasmic reticulum, Cytosol" "HPA018897: AB_1846558, HPA074629: " "unprognostic (8.15e-3)" "unprognostic (1.82e-2)" "unprognostic (1.32e-1)" "unprognostic (2.67e-3)" "unprognostic (2.74e-2)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (1.31e-1)" "unprognostic (6.93e-2)" "unprognostic (7.99e-2)" "unprognostic (1.73e-3)" "unprognostic (2.66e-2)" "prognostic favorable (1.50e-5)" "unprognostic (8.01e-2)" "unprognostic (1.53e-1)" "unprognostic (4.14e-2)" "unprognostic (1.38e-1)" 18.8 38.1 21.2 18.1 20.6 6.3 13.5 24.1 23.0 22.0 25.6 191.2 703.3 14.6 14.4 132.7 17.9 19.5 51.4 22.1 20.6 96.5 345.7 15.6 11.9 20.8 20.8 17.0 14.4 38.0 15.7 10.1 20.6 16.7 178.8 16.2 32.9 15.0 33.8 32.7 576.5 19.7 20.0 12.4 41.6 9.3 20.9 13.1 27.9 14.3 20.8 13.7 33.5 20.5 11.6 16.6 18.4 25.9 19.5 17.9 14.5 15.9 25.8 17.6 22.1 17.3 23.5 15.7 14.3 20.9 13.3 35.4 14.2 39.8 15.3 10.7 18.9 14.4 9.6 44.2 26.3 21.6 26.3 25.4 82.5 26.0 46.7 24.6 14.1 11.3 22.2 10.9 35.7 9.1 17.7 21.4 10.8 16.3 18.8 20.9 19.1 19.8 60.7 18.6 11.6 16.0 50.9 12.6 14.5 8.1 21.0 26.5 17.5 22.4 12.6 15.3 11.1 23.3 24.0 18.4 36.7 17.3 17.4 4.1 5.4 1.6 5.1 3.8 4.5 3.0 4.1 5.8 4.5 3.1 4.8 4.5 1.6 4.3 4.1 4.3 3.2 3.1 21.2 20.6 24.1 23.0 22.1 20.6 20.8 20.8 20.6 20.0 20.9 20.5 13.2 32.1 24.6 8.8 18.8 19.5 13.5 32.8 39.3 31.2 12.4 18.3 33.6 115.8 19.8 53.3 20.9 16.1 12.9 794.4 37.2 24.6 2.1 26.9 15.0 14.1 24.1 7.8 7.0 33.8 5.7 15.3 60.6 33.7 27.3 80.7 28.5 518.5 19.6 28.6 9.7 196.0 18.3 37.0 9.6 2.3 18.6 15.3 10.6 10.3 19.5 19.0 21.6 8.0 5.9 51.8 519.2 18.0 8.5 19.1 2529.8 176.0 85.4 24.2 32.9 19.5 15.2 47.2 19.7 116.1 20.5 13.5 13.0 22.1 499.5 16.7 CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961245-66975149 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.2;liver: 52.5;skeletal muscle: 24.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 120.1;Granulosa cells: 58.5;Hepatocytes: 53.4;Intestinal goblet cells: 32.0;Paneth cells: 67.0;Proximal enterocytes: 66.0;Undifferentiated cells: 44.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 7.4;Daudi: 8.5;JURKAT: 13.5;U-937: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" NA NA 1200000 "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear membrane, Endoplasmic reticulum" "HPA041008: AB_2677247, HPA041307: AB_2677400" "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favorable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" 0.8 0.5 3.1 3.2 2.7 0.9 2.3 2.5 2.9 1.3 1.3 38.2 30.0 0.7 0.2 4.2 2.9 0.9 0.7 3.8 2.0 12.2 52.5 0.7 0.3 3.3 2.7 0.6 4.1 1.0 1.9 0.6 3.5 0.5 31.3 0.6 12.0 0.3 24.7 1.2 23.7 1.2 1.4 0.4 7.7 1.1 2.2 0.2 0.4 1.5 0.2 0.1 0.8 2.2 0.4 3.1 0.3 7.4 0.2 0.2 1.2 0.2 0.2 0.3 0.5 0.5 3.8 8.5 2.4 0.0 0.2 0.6 1.1 0.5 0.1 1.5 5.5 4.3 1.3 2.6 0.0 0.9 0.7 0.3 0.9 0.8 0.1 0.2 0.0 13.5 2.8 1.7 0.3 1.1 1.4 1.4 1.5 2.6 0.4 1.3 0.7 1.3 0.1 0.4 0.4 0.8 0.2 5.8 0.2 0.6 5.0 6.5 0.3 0.4 2.4 0.7 0.2 0.9 3.6 1.3 0.3 7.2 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 3.1 2.7 2.5 2.9 3.8 2.0 3.3 2.7 3.5 1.4 2.2 2.2 0.1 3.2 6.7 0.7 0.4 0.5 0.0 1.3 1.2 0.2 9.1 5.7 1.4 2.8 0.9 0.0 0.0 0.0 0.0 120.1 0.0 0.2 0.5 3.2 0.3 0.2 19.7 0.0 1.8 0.9 0.0 0.2 11.7 4.4 1.3 58.5 0.4 53.4 0.3 0.0 2.9 32.0 0.0 3.2 0.9 5.4 0.0 0.9 0.0 0.0 0.0 0.4 0.0 1.5 0.1 1.0 67.0 1.2 0.1 0.1 66.0 9.9 4.8 0.2 0.0 0.6 0.2 2.3 2.9 1.1 0.3 0.0 0.4 0.1 44.3 0.2 CES4A "CES8, FLJ37464" ENSG00000172824 "Carboxylesterase 4A" Q5XG92 16 66988589-67009758 "Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 16.9;skin 1: 13.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 44.4;Excitatory neurons: 53.6;Oligodendrocytes: 37.6;Respiratory ciliated cells: 47.1" "Cancer enhanced" "Detected in many" "renal cancer: 5.3" "Region enhanced" "Detected in many" "white matter: 10.2" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HDLM-2: 19.1;HMC-1: 5.2;PC-3: 4.5;SiHa: 7.8;SK-BR-3: 5.7;U-266/70: 5.9" "Not detected" "Not detected" HPA035701 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "HPA035701: AB_10696357" "unprognostic (6.34e-2)" "unprognostic (2.09e-1)" "unprognostic (3.18e-1)" "unprognostic (3.26e-2)" "unprognostic (1.99e-1)" "unprognostic (6.20e-2)" "unprognostic (2.12e-2)" "unprognostic (2.04e-2)" "unprognostic (5.78e-3)" "unprognostic (3.93e-2)" "unprognostic (2.02e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (2.35e-6)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-3)" 3.6 1.5 1.2 0.8 2.6 1.2 2.5 0.1 2.5 1.0 0.0 0.6 0.8 0.5 3.9 1.0 16.9 0.8 2.4 2.3 1.0 2.6 8.4 1.5 0.7 1.7 0.2 1.0 1.1 3.1 3.6 1.0 1.2 0.9 0.7 0.8 4.3 2.1 4.9 13.6 0.8 0.3 0.0 0.5 1.4 0.8 0.8 0.7 2.7 0.2 0.9 1.2 0.7 10.2 0.2 1.5 0.1 0.0 0.9 0.8 0.0 0.4 0.7 0.1 0.0 0.0 2.3 0.0 0.0 1.5 0.0 0.7 0.0 0.2 0.0 19.1 0.0 0.0 1.2 0.0 0.1 0.0 5.2 1.8 3.5 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 4.5 0.2 0.0 1.1 0.0 0.3 1.4 0.9 7.8 5.7 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 5.9 2.2 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.5 2.5 0.5 0.6 1.0 0.5 0.8 0.0 0.9 0.2 0.0 0.0 3.5 1.2 0.3 0.7 1.2 2.6 0.1 2.5 2.3 1.0 1.7 0.2 1.2 0.0 0.8 10.2 0.4 0.0 11.4 2.0 3.5 5.4 5.7 5.0 3.4 23.1 44.4 7.7 2.8 4.3 7.3 5.5 14.6 4.7 3.9 4.1 1.9 0.9 1.7 9.9 1.4 1.0 9.0 0.0 53.6 1.6 0.9 3.9 3.1 11.1 9.5 4.9 1.1 22.1 5.6 0.0 29.7 1.8 4.1 4.1 2.1 1.2 13.7 3.2 0.0 4.7 5.7 8.3 4.1 6.6 37.6 0.9 9.7 12.8 1.3 3.5 5.8 1.5 47.1 15.3 0.0 1.5 1.8 32.1 11.8 4.1 5.3 4.5 3.3 13.5 3.5 7.5 CES5A "CAUXIN, CES4C1, CES5, CES7, FLJ31547" ENSG00000159398 "Carboxylesterase 5A" Q6NT32 16 55846154-55956031 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "epididymis: 67.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.5;Collecting duct cells: 5.5;Excitatory neurons: 1.4;Hepatocytes: 6.9;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 4.0" "Cancer enriched" "Detected in single" 5 "liver cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 46 "U-266/70: 7.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 29: U-266 - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (2.07e-1)" "unprognostic (2.55e-1)" "unprognostic (6.34e-2)" "unprognostic (4.82e-2)" "unprognostic (3.78e-1)" "unprognostic (2.33e-1)" "unprognostic (3.12e-2)" "unprognostic (1.72e-7)" "unprognostic (1.55e-2)" "unprognostic (2.27e-1)" 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 67.5 0.0 0.0 0.6 0.1 0.1 0.2 0.0 3.9 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.2 0.1 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CETP BPIFF ENSG00000087237 "Cholesteryl ester transfer protein" P11597 16 56961923-56983845 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 33.5;liver: 43.0;lymphoid tissue: 59.6;placenta: 36.2" "Group enriched" "Detected in some" 6 "Adipocytes: 48.6;Hepatic stellate cells: 75.0;Kupffer cells: 142.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.3;plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 2.3;HUVEC TERT2: 4.7;TIME: 2.8" "Secreted to blood" NA NA 2470000000 360000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.52e-2)" "unprognostic (4.17e-3)" "unprognostic (2.48e-1)" "unprognostic (1.00e-1)" "unprognostic (4.01e-3)" "unprognostic (4.03e-3)" "unprognostic (3.56e-2)" "unprognostic (1.41e-1)" "unprognostic (3.05e-3)" "unprognostic (4.92e-3)" "unprognostic (7.17e-3)" "unprognostic (2.62e-1)" "unprognostic (7.62e-2)" "unprognostic (2.20e-2)" "unprognostic (4.08e-2)" "unprognostic (7.34e-2)" "unprognostic (9.97e-2)" 33.5 2.0 0.7 3.8 0.7 5.7 6.6 0.7 1.4 0.3 0.7 0.6 0.9 0.7 0.0 0.3 0.3 4.0 0.7 0.6 0.8 3.7 43.0 2.8 43.3 1.1 0.8 0.3 0.5 1.8 3.1 36.2 0.9 0.3 0.5 0.0 0.7 0.5 0.3 0.4 1.9 0.8 0.8 59.6 0.4 0.3 0.9 2.3 5.2 0.3 7.6 1.5 0.1 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.2 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.8 0.1 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.3 0.1 0.0 0.0 0.1 1.8 2.3 3.2 0.0 1.2 0.7 0.7 0.7 1.4 0.6 0.8 1.1 0.8 0.9 0.8 0.9 0.8 48.6 0.0 1.8 0.0 1.5 0.5 0.0 0.0 0.0 0.1 0.4 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 13.4 0.0 5.3 0.1 0.9 0.4 0.2 0.0 0.1 0.0 0.0 75.0 1.3 3.1 0.0 0.1 0.2 0.0 142.0 1.2 0.7 0.0 2.1 0.0 0.0 1.4 0.0 1.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.1 0.6 0.0 0.4 0.0 0.4 1.3 0.0 0.0 CFAP157 C9orf117 ENSG00000160401 "Cilia and flagella associated protein 157" Q5JU67 9 127706988-127716002 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.6;choroid plexus: 35.9;fallopian tube: 59.5" "Group enriched" "Detected in some" 4 "Early spermatids: 56.8;Endometrial ciliated cells: 153.5;Late spermatids: 85.0;Respiratory ciliated cells: 189.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 7.3;HeLa: 6.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA021474, HPA021786" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA021474: AB_1845801, HPA021786: AB_1845802" "unprognostic (1.69e-1)" "unprognostic (2.80e-2)" "unprognostic (2.41e-2)" "prognostic favorable (1.45e-4)" "unprognostic (3.02e-1)" "unprognostic (1.58e-1)" "unprognostic (4.71e-3)" "unprognostic (1.49e-1)" "unprognostic (3.14e-4)" "unprognostic (7.72e-2)" "unprognostic (4.93e-4)" "unprognostic (9.32e-3)" "unprognostic (4.95e-3)" "unprognostic (5.71e-4)" "unprognostic (4.34e-2)" "unprognostic (7.38e-2)" "unprognostic (1.28e-1)" 0.2 0.3 2.4 0.1 1.4 0.1 0.2 0.8 0.4 9.1 35.9 0.1 0.0 1.1 1.8 0.8 59.5 0.6 0.3 3.2 3.3 0.5 0.1 11.2 0.4 12.6 18.6 0.4 1.1 0.2 4.7 0.2 7.2 0.3 0.0 0.1 0.5 0.2 0.3 0.6 0.1 0.1 7.5 0.3 0.2 10.1 2.6 0.1 0.4 0.0 0.0 0.4 0.1 1.9 1.4 7.3 0.9 1.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 0.8 0.8 1.4 1.0 0.0 1.6 3.6 0.0 0.0 0.0 2.8 1.2 0.8 6.2 1.7 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.5 0.0 2.1 2.9 0.4 0.0 5.0 1.1 0.4 0.7 1.5 3.6 2.0 1.1 1.2 0.0 0.3 5.1 1.0 1.7 2.9 0.4 0.1 2.4 0.4 1.5 1.6 1.4 4.1 0.8 0.7 2.3 0.9 0.7 0.9 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.4 0.8 0.4 3.2 3.3 12.6 18.6 7.2 7.5 2.6 1.9 0.2 9.6 10.5 0.0 0.0 0.0 0.3 0.0 0.0 0.7 1.3 0.6 0.0 0.0 27.9 0.0 0.0 0.1 0.1 0.2 1.9 0.3 56.8 153.5 1.9 0.8 0.0 0.0 0.0 0.0 0.1 1.0 0.0 4.8 2.5 0.1 0.4 0.2 0.2 0.0 0.0 0.6 0.0 0.6 0.0 85.0 0.3 0.5 0.0 0.0 0.0 0.8 1.0 0.0 0.0 0.0 0.1 0.7 0.1 0.4 0.5 0.4 189.5 0.4 0.0 0.4 0.3 14.3 0.9 0.0 0.0 0.0 0.3 1.4 0.3 0.2 CFAP65 "CCDC108, DKFZp434O0527, MGC35338" ENSG00000181378 "Cilia and flagella associated protein 65" Q6ZU64 2 219002846-219041527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.1;choroid plexus: 13.5;fallopian tube: 25.7;testis: 9.4" "Group enriched" "Detected in many" 4 "Early spermatids: 204.5;Late spermatids: 164.3" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 10.8" "HPA055156, HPA063406" Uncertain Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "HPA055156: AB_2682720, HPA063406: " "unprognostic (3.95e-2)" "unprognostic (1.80e-1)" "unprognostic (9.88e-3)" "prognostic favorable (6.08e-5)" "unprognostic (2.18e-2)" "unprognostic (1.04e-2)" "unprognostic (2.20e-1)" "unprognostic (3.76e-3)" "unprognostic (3.71e-1)" "unprognostic (3.03e-1)" "unprognostic (5.58e-3)" "unprognostic (1.43e-1)" "unprognostic (6.62e-3)" "unprognostic (8.04e-2)" "unprognostic (2.81e-2)" "unprognostic (9.60e-2)" "unprognostic (6.60e-2)" 0.0 0.1 2.3 0.0 2.1 0.0 0.1 1.0 1.0 1.3 13.5 0.1 0.0 0.5 1.8 0.0 25.7 0.4 0.0 2.6 2.8 0.4 0.0 2.7 0.0 8.4 12.1 0.0 0.3 0.1 3.5 0.0 6.2 0.1 0.2 9.2 0.1 0.1 0.0 0.0 0.4 0.0 6.1 0.0 0.3 9.4 2.4 0.0 0.9 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.1 1.0 1.0 2.6 2.8 8.4 12.1 6.2 6.1 2.4 3.2 0.1 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.8 7.7 8.8 0.0 4.3 6.8 0.0 12.5 0.0 0.1 1.1 0.0 0.6 204.5 45.1 0.5 0.2 29.1 0.0 0.0 1.5 0.0 0.2 2.0 1.8 0.0 0.2 0.0 0.1 0.1 0.0 0.0 25.2 0.0 0.0 0.0 164.3 0.6 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 1.8 0.7 0.0 1.1 1.9 1.1 29.2 19.5 0.0 0.1 0.0 14.4 5.7 0.0 0.0 0.0 0.2 0.1 5.1 0.1 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 2613.2" "Cell type enhanced" "Detected in many" "Ductal cells: 873.6;Exocrine glandular cells: 197.3;Hepatocytes: 284.0;Pancreatic endocrine cells: 318.0;Proximal enterocytes: 139.7" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 15.0;ASC TERT1: 23.0;EFO-21: 25.1;fHDF/TERT166: 14.1;HSkMC: 19.1;U-87 MG: 10.1" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" NA NA 879000000 120000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 143.7 18.0 3.6 32.8 3.6 0.1 28.5 3.4 9.9 16.3 3.9 22.3 28.1 8.2 14.2 24.1 53.7 0.8 42.6 3.7 3.4 58.7 2613.2 39.2 4.2 4.1 3.7 9.9 51.8 0.2 17.7 5.0 3.8 60.3 14.5 1.4 43.3 0.0 3.0 7.7 73.1 48.3 3.4 12.9 54.5 2.1 3.7 1.9 15.5 0.7 6.7 17.8 9.2 3.6 0.5 1.9 0.1 0.0 15.0 23.0 0.1 0.0 0.2 1.1 0.0 0.1 8.6 0.1 25.1 14.1 0.6 6.0 0.0 1.8 1.2 1.0 0.3 0.7 0.4 0.5 0.0 1.0 0.4 19.1 0.4 0.6 0.5 1.3 0.2 0.1 0.3 0.7 0.1 0.2 0.1 0.3 0.4 0.0 0.4 0.3 0.3 1.3 1.7 0.5 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 3.4 1.2 0.4 0.4 0.7 2.1 1.0 10.1 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 3.6 3.4 9.9 3.7 3.4 4.1 3.7 3.8 3.4 3.7 3.6 1.0 0.0 16.9 0.0 2.6 0.8 0.9 64.8 11.4 0.3 4.9 0.9 0.4 44.3 127.3 5.5 0.0 0.1 0.0 3.7 3.9 873.6 0.0 1.9 0.4 3.9 2.4 16.0 0.2 197.3 0.2 34.6 20.9 1.2 0.0 0.0 11.7 284.0 1.0 0.0 0.2 8.5 18.3 19.7 1.0 0.0 2.8 1.1 0.0 5.6 18.1 0.4 0.0 0.0 0.0 318.0 10.6 0.0 0.1 8.6 139.7 17.1 75.4 0.7 0.0 1.0 12.6 0.1 0.1 3.9 1.8 1.6 1.6 0.0 12.4 4.5 CFC1 "CRYPTIC, HTX2" ENSG00000136698 "Cripto, FRL-1, cryptic family 1" P0CG37 2 130592165-130599575 "Disease related genes, Human disease related genes, Predicted secreted proteins" Gastrulation "Developmental protein" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 24.0;pancreas: 30.7;pituitary gland: 59.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 14.9;Enteroendocrine cells: 20.5" "Cancer enriched" "Detected in some" 7 "pancreatic cancer: 4.3" "Region enhanced" "Detected in all" "hypothalamus: 24.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "RPMI-8226: 12.1;SCLC-21H: 6.7;SuSa: 4.0" HPA041773 Uncertain "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA041773: AB_2677664" "unprognostic (6.65e-2)" "unprognostic (2.19e-3)" "unprognostic (1.11e-3)" "unprognostic (2.01e-1)" 1.7 0.6 4.6 0.0 2.3 0.0 0.0 2.9 3.5 0.1 0.0 0.2 0.0 0.2 0.1 0.0 1.5 0.0 1.9 1.3 24.0 0.0 0.0 0.1 0.0 3.9 8.1 0.0 30.7 0.0 59.3 0.0 5.6 7.2 0.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 10.7 0.6 8.6 5.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 2.3 2.9 3.5 1.3 24.0 3.9 8.1 5.6 3.9 8.6 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 20.5 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CFC1B ENSG00000152093 "Cripto, FRL-1, cryptic family 1B" P0CG36 2 130521197-130528604 "Predicted secreted proteins" Gastrulation "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "pituitary gland: 2.4" "Cell type enriched" "Detected in single" 9 "Bipolar cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041773 Approved "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 56: Bipolar cells - Visual perception" "HPA041773: AB_2677664" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 2.4 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859664-863641 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1496.7;breast: 993.2" "Group enriched" "Detected in many" 6 "Fibroblasts: 9365.5;Leydig cells: 5032.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 297.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.6" "Group enriched" "Detected in many" 5 "ASC diff: 197.4;THP-1: 342.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 732000000 4400000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favorable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 1496.7 33.3 1.5 9.6 1.6 10.7 993.2 1.2 2.4 597.4 3.7 324.8 23.5 58.4 2.4 212.8 258.0 9.6 854.2 1.7 2.3 18.1 8.7 363.3 2.1 3.3 2.3 74.3 41.4 1.7 9.0 14.5 3.6 277.8 10.9 0.6 247.3 6.3 197.0 488.6 248.4 4.0 2.6 28.6 263.8 51.8 2.9 3.6 332.3 26.9 0.8 848.3 729.8 5.8 3.9 5.2 0.6 2.2 197.4 26.2 9.5 0.8 0.0 0.0 0.0 0.8 0.4 0.2 5.7 0.0 0.5 3.0 1.8 0.5 0.0 5.7 14.5 0.5 12.3 3.8 3.6 2.5 4.9 8.7 0.2 0.1 0.0 0.8 0.0 4.5 11.9 0.9 0.0 2.6 0.6 49.2 1.0 4.5 16.1 1.3 0.5 5.2 0.3 1.2 1.8 1.8 5.5 1.9 0.5 0.6 7.5 342.2 0.4 0.2 5.1 2.9 0.6 7.8 4.7 0.4 0.2 20.8 0.2 297.6 41.2 127.8 8.4 55.5 13.2 5.7 4.2 10.2 14.5 1.4 9.7 9.7 112.0 1.3 57.3 1.8 4.7 37.8 1.5 1.6 1.2 2.4 1.7 2.3 3.3 2.3 3.6 2.6 2.9 5.8 857.8 9.6 23.3 0.0 19.2 785.5 49.0 10.1 17.1 2.9 107.3 120.1 55.5 21.5 30.9 18.4 2.1 36.6 40.0 33.1 11.7 7.7 27.1 23.1 593.3 114.8 4.2 8.2 0.2 0.0 32.9 9365.5 113.6 15.9 17.1 0.9 30.4 2.6 272.4 1.7 0.4 8.7 0.0 424.7 1145.2 89.6 5032.4 442.5 642.1 4.7 303.6 1.3 21.6 0.0 0.1 2.9 64.8 283.2 41.0 19.7 4.3 3.4 28.4 6.5 0.0 414.3 530.2 11.4 21.3 28.6 735.9 34.3 82.8 1.2 21.0 233.2 CFDP1 "BCNT, CENP-29, CP27, p97, SWC5, Yeti" ENSG00000153774 "Craniofacial development protein 1" Q9UEE9 16 75293698-75433503 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 493.3;Paneth cells: 745.2;Proximal enterocytes: 612.2;Proximal tubular cells: 637.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041316, HPA048242" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA041316: AB_10794371, HPA048242: AB_2680327" "unprognostic (1.45e-1)" "unprognostic (8.64e-2)" "unprognostic (1.13e-1)" "unprognostic (4.88e-1)" "unprognostic (3.97e-2)" "prognostic unfavorable (9.63e-5)" "unprognostic (5.81e-3)" "unprognostic (2.17e-1)" "unprognostic (1.26e-2)" "unprognostic (2.61e-2)" "unprognostic (1.42e-1)" "unprognostic (7.37e-2)" "unprognostic (2.85e-2)" "unprognostic (6.54e-2)" "unprognostic (1.36e-1)" "unprognostic (4.92e-3)" "unprognostic (1.25e-1)" 45.0 51.0 57.4 24.0 58.0 35.0 45.2 60.8 75.3 69.1 57.9 47.5 30.4 58.6 62.3 41.2 55.6 29.7 36.8 57.1 61.7 64.5 43.1 37.3 27.1 58.8 59.3 83.1 41.2 30.8 57.1 63.1 58.8 39.9 40.2 49.6 39.4 38.1 35.7 42.4 36.4 51.0 56.7 30.2 34.7 59.5 59.6 57.0 45.0 34.9 35.8 44.8 50.7 60.8 65.0 47.6 158.9 59.2 141.2 156.3 47.2 63.2 74.1 83.0 119.1 82.5 86.6 61.3 91.1 79.3 92.7 71.5 123.3 101.9 164.9 26.4 58.6 63.0 46.6 177.2 97.3 69.2 51.6 98.4 85.5 100.2 121.4 144.6 91.5 114.0 91.3 28.3 93.9 149.0 102.2 152.6 77.1 110.0 24.8 182.7 64.3 108.5 93.1 35.5 94.5 79.4 105.7 22.3 92.5 136.4 91.8 121.6 53.8 59.2 63.1 63.2 40.8 54.4 89.2 228.6 59.3 89.9 53.3 61.3 45.5 60.8 31.2 47.8 44.5 33.6 42.7 34.7 48.8 35.4 38.7 36.5 38.1 28.5 46.2 48.7 68.5 25.8 57.4 58.0 60.8 75.3 57.1 61.7 58.8 59.3 58.8 56.7 59.6 60.8 87.4 38.5 57.5 37.5 45.5 57.9 116.3 135.9 47.3 87.2 89.5 103.4 34.7 91.5 111.2 115.8 116.7 119.0 50.5 493.3 197.6 79.1 133.7 197.7 118.5 97.6 82.2 78.9 49.5 94.9 114.0 82.9 61.2 121.3 28.5 194.5 62.8 153.9 77.1 62.2 50.5 219.2 59.0 53.1 44.5 69.7 125.2 51.1 33.8 45.9 64.8 60.8 84.5 49.8 75.6 92.4 745.2 112.5 42.3 116.9 612.2 637.6 205.3 112.5 98.6 55.3 88.2 311.2 178.0 49.5 65.6 154.9 51.6 103.5 120.0 130.4 CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196652043-196747504 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1676.3" "Group enriched" "Detected in many" 4 "Fibroblasts: 448.0;Hepatocytes: 1114.8;Leydig cells: 283.9" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 18.7" "Lineage enriched" "Detected in single" 26 "T-cells: 18.7" "Cell line enhanced" "Detected in many" "HHSteC: 123.1;HSkMC: 119.5;hTERT-RPE1: 374.9;RT4: 227.0" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" NA NA 396000000000 100000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" 125.3 42.1 18.1 32.7 21.5 1.3 66.9 20.0 29.6 76.8 43.0 51.0 30.5 12.8 15.9 63.8 24.2 133.6 301.5 18.1 18.6 25.5 1676.3 70.8 27.4 19.3 19.0 165.1 14.0 6.4 16.0 26.1 19.9 23.0 80.2 4.3 126.7 24.0 21.1 74.5 52.1 32.5 19.5 13.9 46.9 14.3 21.6 12.1 102.5 84.0 25.9 149.9 27.0 21.1 0.0 64.9 0.0 0.0 96.5 54.7 0.1 25.8 63.1 3.5 13.5 0.1 11.9 0.3 9.6 0.1 0.2 2.2 0.0 23.6 2.6 1.3 0.0 20.0 74.7 0.0 123.1 0.9 0.3 119.5 0.3 18.4 7.9 374.9 79.2 0.0 74.4 2.7 89.4 0.1 0.5 0.1 0.4 0.0 0.1 0.2 89.8 21.0 0.0 227.0 0.0 0.1 0.4 0.0 0.1 0.6 0.1 0.0 5.6 73.6 0.9 0.8 0.8 0.8 0.0 0.3 13.1 0.2 5.8 0.0 0.1 0.0 2.0 0.0 18.7 0.0 6.6 4.0 0.2 0.0 0.4 1.5 0.7 0.0 0.0 0.0 0.0 1.1 18.1 21.5 20.0 29.6 18.1 18.6 19.3 19.0 19.9 19.5 21.6 21.1 73.9 9.6 17.6 0.7 4.2 44.2 63.6 140.6 14.2 2.4 1.3 3.4 10.9 35.8 141.1 5.5 0.0 0.0 3.1 0.1 0.0 6.2 2.6 2.3 3.8 49.8 0.0 52.6 0.6 0.8 0.0 448.0 8.6 1.9 3.8 6.9 47.8 1114.8 1.1 0.0 1.0 0.0 14.2 43.8 62.1 7.4 283.9 5.7 44.4 38.4 0.3 0.3 0.0 0.0 0.2 5.3 0.0 138.8 2.6 13.0 0.0 0.5 115.6 1.4 6.6 94.2 59.6 1.4 1.0 10.9 38.2 0.1 13.2 26.3 0.0 61.5 CFHR1 "CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2" ENSG00000244414 "Complement factor H related 1" Q03591 1 196819731-196832189 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 272 "liver: 2081.3" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 320.0" "Cancer enriched" "Detected in single" 798 "liver cancer: 182.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HeLa: 1.2;HL-60: 2.0;U-266/70: 2.4" "Not detected" "Not detected" "HPA038915, HPA038922, HPA040726" Supported Approved Vesicles "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA038915: AB_2676269, HPA038922: AB_2676271, HPA040726: AB_2677101" "unprognostic (2.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.50e-2)" "unprognostic (1.88e-2)" "prognostic favorable (8.71e-6)" "unprognostic (3.02e-1)" "unprognostic (3.70e-1)" "unprognostic (2.50e-1)" "unprognostic (8.48e-2)" "unprognostic (7.21e-4)" "unprognostic (7.01e-4)" "unprognostic (1.13e-1)" "unprognostic (6.41e-2)" 1.5 0.6 0.1 1.8 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.2 7.6 2081.3 0.1 6.7 0.1 0.8 0.3 0.3 0.0 0.1 0.1 0.4 0.2 0.2 0.2 0.1 0.0 0.2 0.1 0.7 0.2 0.1 6.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.9 0.3 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.1 0.1 0.0 2.4 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.4 0.1 0.2 0.1 0.5 3.2 0.0 0.0 2.2 0.4 0.1 0.0 0.0 1.2 0.0 0.1 1.8 11.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 18.7 0.0 0.0 0.0 9.9 0.0 0.0 0.0 6.0 15.0 320.0 5.6 0.0 0.4 0.0 0.0 16.9 0.4 0.2 1.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 41.0 2.1 0.3 1.5 0.0 0.0 0.3 1.4 5.6 0.1 0.1 CFHR2 "CFHL2, FHR2, HFL3" ENSG00000080910 "Complement factor H related 2" P36980 1 196943738-196959622 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2752 "liver: 1311.8" "Cell type enriched" "Detected in some" 14 "Hepatocytes: 38.5" "Cancer enriched" "Detected in single" 175 "liver cancer: 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038915, HPA040726, HPA049813" Supported "Secreted to blood" NA NA 4800000000 "Cluster 6: Non-specific - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 15: Hepatocytes - Hemostasis" "HPA038915: AB_2676269, HPA040726: AB_2677101, HPA049813: AB_2680895" "unprognostic (1.25e-2)" 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 1311.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 38.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CFHR3 "CFHL3, DOWN16, FHR-3, FHR3, HLF4" ENSG00000116785 "Complement factor H related 3" Q02985 1 196774813-196795407 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 582 "liver: 505.7" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 205.5" "Cancer enriched" "Detected in single" 80 "liver cancer: 27.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.7;SuSa: 1.5;T-47d: 3.6;U-266/70: 6.4" "Secreted to blood" NA NA 582000000 3100000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.73e-1)" "unprognostic (2.11e-1)" "unprognostic (7.16e-2)" "unprognostic (6.77e-2)" "unprognostic (4.46e-1)" "unprognostic (4.20e-3)" "prognostic favorable (2.86e-5)" "unprognostic (1.78e-1)" "unprognostic (2.05e-2)" "unprognostic (1.98e-1)" "unprognostic (1.19e-2)" "unprognostic (6.11e-3)" "unprognostic (2.06e-10)" "unprognostic (2.67e-4)" "unprognostic (3.00e-1)" "unprognostic (3.29e-2)" "unprognostic (1.32e-1)" 0.8 0.2 0.1 0.2 0.2 0.1 0.2 0.0 0.4 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.4 505.7 0.2 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.1 0.1 0.3 0.0 0.3 0.1 0.0 0.4 0.1 0.6 0.0 0.7 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.4 0.0 0.9 0.0 0.0 0.0 0.3 0.0 1.5 3.6 0.0 0.0 0.1 0.2 0.3 0.0 6.4 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.5 1.8 16.0 0.1 0.0 0.1 1.7 0.0 0.0 0.0 0.0 7.1 205.5 0.0 0.0 0.1 0.0 0.0 8.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.7 CFHR4 "CFHL4, FHR-4, FHR4" ENSG00000134365 "Complement factor H related 4" Q92496 1 196888014-196918713 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 432 "liver: 123.9" "Cell type enriched" "Detected in some" 28 "Hepatocytes: 62.6" "Cancer enriched" "Detected in single" 145 "liver cancer: 13.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.3" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 170000000 "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (5.97e-1)" "prognostic favorable (1.57e-6)" "unprognostic (1.89e-1)" "unprognostic (4.79e-2)" "unprognostic (1.26e-1)" "unprognostic (1.68e-2)" "unprognostic (4.71e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 123.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.7 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 2.2 62.6 0.0 0.0 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CFHR5 "CFHL5, FHR-5, FHR5" ENSG00000134389 "Complement factor H related 5" Q9BXR6 1 196977556-197009678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1675 "liver: 167.5" "Cell type enriched" "Detected in some" 19 "Hepatocytes: 102.7" "Cancer enriched" "Detected in single" 396 "liver cancer: 57.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038915, HPA040726" Supported "Secreted to blood" NA NA 1900000000 "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" "HPA038915: AB_2676269, HPA040726: AB_2677101" "unprognostic (9.12e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 102.7 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109801999 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1098.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 108.7;Hepatocytes: 592.5;Muller glia cells: 147.8;Proximal tubular cells: 223.6" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 106.1;Hep G2: 179.8;HSkMC: 67.4;RPTEC TERT1: 190.6" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" NA NA 12000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" 45.1 50.2 8.1 12.6 8.2 0.1 17.4 7.7 13.2 36.8 10.4 7.4 38.0 39.2 80.3 9.3 74.0 73.0 25.0 8.3 9.6 224.9 1098.8 50.7 8.9 15.6 10.2 32.1 26.0 3.1 8.4 24.1 10.7 8.3 6.4 53.0 15.0 26.7 3.9 2.7 22.3 24.3 10.5 33.1 14.4 8.8 9.2 2.3 14.5 4.6 7.5 34.1 8.3 10.6 0.0 0.6 0.0 0.3 0.0 0.2 0.1 1.5 1.4 0.1 0.2 0.0 106.1 0.0 32.9 0.0 0.5 0.0 0.0 0.0 0.0 34.8 0.7 0.0 0.4 179.8 6.2 0.3 0.0 67.4 0.0 0.1 0.0 3.6 4.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 190.6 0.5 0.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.0 0.1 18.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 8.2 7.7 13.2 8.3 9.6 15.6 10.2 10.7 10.5 9.2 10.6 48.1 12.8 50.9 3.6 4.0 1.0 12.2 15.2 0.6 3.4 2.1 5.6 2.3 108.7 36.2 64.4 2.1 0.1 0.3 1.7 31.3 69.3 0.2 34.1 46.4 57.7 0.0 2.7 0.3 30.9 0.2 34.3 8.2 33.6 3.8 72.1 55.0 592.5 0.7 1.7 0.2 1.9 0.0 16.7 1.5 0.8 16.8 2.0 0.0 4.7 1.6 147.8 0.0 0.0 0.3 30.8 2.4 0.0 0.0 3.8 17.0 223.6 8.4 7.3 0.0 1.3 9.4 1.6 0.5 1.9 1.1 0.3 3.4 18.5 4.1 12.6 CFP PFC ENSG00000126759 "Complement factor properdin" P27918 X 47623172-47630305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 83.9;lymphoid tissue: 58.4" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 108.1;Kupffer cells: 356.7;Langerhans cells: 164.1;Macrophages: 177.3;monocytes: 473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 8 "classical monocyte: 1167.5;intermediate monocyte: 1273.6;myeloid DC: 994.5;neutrophil: 730.3;non-classical monocyte: 868.9" "Group enriched" "Detected in all" 46 "dendritic cells: 994.5;granulocytes: 730.3;monocytes: 1273.6" "Cell line enhanced" "Detected in some" "EFO-21: 20.7;HEL: 5.0;HMC-1: 5.5;NB-4: 10.7;U-937: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072644 Approved Vesicles "Secreted to blood" NA NA 6200000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 38: EFO-21 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA072644: " "unprognostic (2.77e-3)" "unprognostic (2.21e-3)" "unprognostic (1.00e-1)" "unprognostic (2.15e-2)" "unprognostic (4.15e-2)" "unprognostic (9.66e-5)" "unprognostic (9.90e-3)" "unprognostic (1.30e-2)" "unprognostic (5.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (2.70e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.62e-2)" "unprognostic (2.17e-1)" 6.0 1.9 0.3 20.5 0.3 83.9 2.1 0.3 0.6 0.6 0.2 2.1 1.2 0.9 0.2 1.6 3.4 2.1 2.6 0.4 0.1 0.8 12.0 9.3 11.7 0.1 0.0 0.7 0.8 0.1 0.8 0.9 0.0 0.7 0.9 0.2 1.0 0.2 1.0 1.5 3.7 5.2 0.0 58.4 1.5 0.6 0.0 5.1 0.9 0.7 4.4 4.9 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 20.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 5.0 0.2 0.0 0.1 1.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.0 10.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.2 1.0 0.0 0.1 0.5 0.1 0.4 0.4 0.1 0.1 7.2 0.0 131.5 1167.5 39.9 3.0 1273.6 2.3 6.7 15.1 1.8 994.5 2.6 21.8 8.1 730.3 12.3 868.9 30.9 14.1 1071.9 0.3 0.3 0.3 0.6 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 9.1 1.0 5.8 4.0 0.1 0.3 1.2 3.4 0.7 0.4 0.9 1.5 2.8 0.0 0.0 0.3 1.7 0.3 0.0 0.2 0.2 0.4 0.4 7.4 0.0 2.5 1.4 0.7 0.5 2.0 1.1 0.6 1.3 4.0 108.1 2.0 17.3 1.7 1.1 0.0 0.0 356.7 164.1 0.3 0.9 177.3 5.4 0.0 473.7 0.3 4.1 2.0 0.3 0.3 0.1 1.2 1.2 0.3 0.1 0.5 7.5 1.9 0.0 1.5 1.2 0.0 0.2 0.5 3.0 0.4 4.8 3.1 0.6 0.0 CGA "FSHA, GPA1, GPHa, GPHA1, HCG, LHA, TSHA" ENSG00000135346 "Glycoprotein hormones, alpha polypeptide" P01215 6 87085498-87095106 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pituitary gland: 4389.4" "Cell type enriched" "Detected in some" 15 "Syncytiotrophoblasts: 85317.2" "Cancer enhanced" "Detected in many" "breast cancer: 10.9;testis cancer: 13.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "BEWO: 776.1;SuSa: 1437.9" "Region enriched" "Detected in many" 6 "hypothalamus: 22.2" "Region enriched" "Detected in many" 40 "hypothalamus: 82.2" "CAB023350, HPA029698" Enhanced "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB023350: AB_617281, HPA029698: AB_2673153" "unprognostic (1.66e-1)" "unprognostic (2.10e-1)" "unprognostic (3.22e-5)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.69e-2)" "unprognostic (3.17e-1)" "unprognostic (7.04e-3)" "unprognostic (1.51e-1)" "unprognostic (2.85e-1)" "unprognostic (4.32e-2)" "unprognostic (8.32e-2)" "unprognostic (9.15e-3)" 0.8 4.1 0.2 0.1 0.4 1.9 0.1 0.7 0.7 0.0 0.3 0.3 0.5 1.0 1.2 1.2 0.1 0.2 1.5 0.3 0.3 2.7 2.0 0.7 0.3 2.1 1.6 0.5 1.3 18.9 4389.4 725.8 0.9 2.7 0.3 0.3 0.5 1.1 3.3 2.1 0.3 3.4 0.1 1.1 38.1 0.5 1.0 0.8 0.5 0.0 0.3 0.4 0.2 1.5 0.0 1.0 0.0 0.1 0.0 0.0 776.1 0.7 0.6 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.9 4.2 1.8 0.3 40.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.2 0.1 0.0 0.3 0.0 0.1 1.0 0.6 0.1 22.6 0.0 1437.9 0.1 0.0 0.0 0.9 0.2 0.4 0.3 3.1 0.4 0.5 0.2 0.0 0.1 0.7 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.3 0.1 0.4 0.2 0.4 0.6 0.2 0.3 0.4 0.1 0.0 0.2 0.4 0.7 0.7 0.3 0.3 2.1 1.6 0.9 0.1 1.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.9 1.9 0.0 0.0 7.3 0.0 1414.2 0.1 0.0 0.0 0.0 0.2 20.2 1.1 22.9 1.8 0.0 0.2 0.0 5400.7 65.5 0.0 28.4 0.0 0.0 0.0 0.0 625.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.0 85317.2 6.0 0.0 0.2 9.9 CGB1 ENSG00000267631 "Chorionic gonadotropin subunit beta 1" A6NKQ9 19 49035569-49036895 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "pancreas: 2.7;pituitary gland: 4.3" "Cell type enriched" "Detected in single" 77 "Syncytiotrophoblasts: 69.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HMC-1: 17.7" "HPA038925, HPA038934" Uncertain Approved Cytosol "Secreted to blood" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.0 3.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 69.9 0.0 0.0 0.0 0.0 CGB2 ENSG00000104818 "Chorionic gonadotropin subunit beta 2" Q6NT52 19 49031890-49033238 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.6" "Cell type enriched" "Detected in some" 6 "Syncytiotrophoblasts: 40.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HMC-1: 29.9;U-266/70: 12.1;U-266/84: 15.6" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (3.05e-2)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.5 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.8 0.7 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 4.1 0.0 0.5 0.0 0.1 0.3 0.0 29.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.3 0.8 0.0 3.9 12.1 15.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.2 0.2 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 1.5 1.8 0.0 0.0 40.0 0.0 0.0 0.0 0.0 CGB3 CGB ENSG00000104827 "Chorionic gonadotropin subunit beta 3" P0DN86 19 49022869-49024333 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 9.8" "Cell type enriched" "Detected in some" 7 "Syncytiotrophoblasts: 865.9" "Group enriched" "Detected in some" 5 "pancreatic cancer: 2.9;testis cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "BEWO: 65.8" "CAB000042, CAB010884, HPA038925, HPA038934" Enhanced Approved Cytosol "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "CAB000042: , CAB010884: AB_259037, HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (1.39e-1)" "unprognostic (7.88e-2)" "unprognostic (6.92e-2)" "unprognostic (1.04e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.3 0.0 2.1 9.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.0 65.8 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.1 0.2 0.1 0.0 0.1 0.0 0.0 1.4 0.6 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.5 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.3 0.2 0.3 0.0 0.3 0.2 0.1 0.4 0.0 0.0 2.1 0.7 0.0 0.0 0.1 0.4 0.0 3.3 1.3 0.9 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 118.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 865.9 0.0 0.0 0.0 0.0 CGB5 HCG ENSG00000189052 "Chorionic gonadotropin subunit beta 5" P0DN86 19 49043848-49045311 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pituitary gland: 8.7;placenta: 25.6" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 19.7" "Cancer enhanced" "Detected in some" "pancreatic cancer: 10.0;testis cancer: 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "BEWO: 120.1;U-251 MG: 53.2" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (1.38e-1)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "prognostic unfavorable (1.18e-5)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.47e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.1 8.7 25.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.4 0.0 0.0 0.0 0.0 120.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.2 0.0 53.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 CGB7 CG-beta-a ENSG00000196337 "Chorionic gonadotropin subunit beta 7" P0DN87 19 49054275-49058860 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 3.2;skin 1: 3.9" "Group enriched" "Detected in some" 5 "Pancreatic endocrine cells: 16.5;Syncytiotrophoblasts: 58.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;HaCaT: 3.1;hTCEpi: 3.2;U-251 MG: 7.5" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (9.53e-2)" "unprognostic (1.99e-1)" "unprognostic (1.87e-1)" "unprognostic (3.53e-1)" "unprognostic (4.60e-5)" "unprognostic (2.64e-1)" "unprognostic (2.46e-1)" "unprognostic (8.37e-2)" "unprognostic (2.88e-2)" "unprognostic (4.80e-2)" "unprognostic (8.83e-4)" "unprognostic (1.54e-1)" "unprognostic (3.89e-8)" "unprognostic (1.63e-2)" "unprognostic (1.94e-1)" "unprognostic (2.05e-1)" "unprognostic (9.28e-2)" 0.1 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.3 1.1 0.2 0.0 0.1 0.1 0.1 2.4 0.6 0.0 0.1 0.2 0.1 0.2 0.0 0.6 0.0 0.1 0.3 0.1 0.7 0.0 1.5 0.4 0.1 3.2 0.0 0.0 1.1 0.4 2.2 3.9 0.0 0.0 0.1 0.1 0.0 1.1 0.1 0.2 0.2 0.1 0.0 1.1 1.8 0.1 2.2 0.3 0.1 1.0 0.0 0.0 2.7 0.3 0.0 0.6 0.8 0.5 1.8 0.0 0.1 0.5 1.2 3.1 0.0 2.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 3.2 0.2 0.4 1.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 1.0 0.0 0.0 1.1 0.6 0.1 0.0 1.5 1.5 0.0 7.5 0.2 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.2 0.0 0.5 0.0 0.0 0.6 0.1 0.6 1.8 0.0 0.1 0.3 0.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 1.2 0.4 0.3 0.0 58.7 0.0 0.0 0.0 0.1 CGB8 ENSG00000213030 "Chorionic gonadotropin subunit beta 8" P0DN86 19 49047638-49049106 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "placenta: 18.8" "Cell type enriched" "Detected in some" 6 "Syncytiotrophoblasts: 44.3" "Cancer enriched" "Detected in some" 4 "testis cancer: 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "BEWO: 157.9;U-251 MG: 57.2" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (7.44e-3)" "unprognostic (4.70e-1)" "unprognostic (1.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 18.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 1.2 0.0 0.0 0.0 0.0 157.9 0.0 0.0 0.6 0.0 0.0 5.3 0.0 0.1 1.0 4.0 1.3 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 10.1 0.2 0.6 0.0 2.8 7.1 0.7 57.2 0.1 0.2 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.3 0.0 0.0 0.0 0.0 CGREF1 CGR11 ENSG00000138028 "Cell growth regulator with EF-hand domain 1" Q99674 2 27098889-27119128 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.3;salivary gland: 25.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 12.6;Excitatory neurons: 16.6;Inhibitory neurons: 15.9;Oligodendrocyte precursor cells: 12.5;Spermatogonia: 16.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 40.1;SK-BR-3: 78.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008241, HPA071103" Uncertain Approved "Golgi apparatus" "Secreted in brain" NA NA 700000 "Cluster 65: Brain - Ion transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA008241: AB_1846605, HPA071103: " "unprognostic (1.39e-2)" "unprognostic (1.26e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (8.45e-2)" "unprognostic (3.99e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (5.22e-2)" "unprognostic (7.34e-2)" "unprognostic (1.92e-1)" "unprognostic (2.57e-1)" "unprognostic (2.27e-1)" "unprognostic (2.52e-3)" "unprognostic (1.05e-1)" "unprognostic (2.30e-2)" "unprognostic (7.24e-4)" "unprognostic (1.20e-2)" 4.2 2.3 20.4 1.0 21.7 1.9 6.3 17.1 28.3 3.5 2.1 2.6 3.9 11.6 1.4 3.5 12.4 3.9 4.9 27.0 18.1 3.8 14.9 1.1 0.5 12.8 12.1 13.9 2.1 0.2 3.3 0.3 12.8 4.2 3.8 3.7 25.3 0.9 6.5 2.3 5.6 5.4 10.2 0.6 11.4 3.8 17.2 0.2 1.8 6.9 0.4 3.7 1.5 16.4 7.6 6.3 0.3 8.1 18.3 6.8 0.7 9.1 0.0 0.8 0.4 1.7 6.2 0.1 2.4 18.2 2.2 0.4 1.4 2.1 0.5 0.7 3.7 0.1 10.4 16.4 16.9 5.3 0.6 4.7 18.1 2.6 2.1 11.6 0.7 1.3 0.2 0.4 1.2 24.0 4.0 6.8 2.1 40.1 16.8 0.3 0.0 0.6 0.1 0.3 17.8 26.6 17.7 78.7 9.4 0.2 25.3 13.3 0.0 0.0 6.9 0.0 0.7 2.3 0.8 0.7 0.0 0.2 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 21.7 17.1 28.3 27.0 18.1 12.8 12.1 12.8 10.2 17.2 16.4 0.1 0.0 0.0 2.6 0.4 0.6 0.2 0.0 1.8 9.2 9.2 12.6 1.4 0.0 0.0 0.0 4.2 0.0 0.1 0.2 0.0 0.1 1.1 0.3 3.0 0.4 0.0 5.5 16.6 1.5 0.2 3.8 4.6 0.1 0.0 0.4 3.6 5.0 0.4 0.0 15.9 6.8 0.0 0.6 0.7 3.1 4.4 0.2 0.0 1.9 0.0 0.5 0.0 12.5 0.8 2.1 0.0 8.6 1.1 1.8 3.4 4.4 0.0 2.2 0.0 1.7 0.7 3.2 16.2 2.2 0.4 0.1 0.1 3.2 0.9 0.1 CHAD SLRR4A ENSG00000136457 Chondroadherin O15335 17 50464496-50468906 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.2;pancreas: 32.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.6;Breast myoepithelial cells: 2.4;Distal enterocytes: 3.3;Gastric mucus-secreting cells: 4.6;Hepatocytes: 2.4;Intestinal goblet cells: 4.3;Oligodendrocyte precursor cells: 5.5;Paneth cells: 2.5;Proximal enterocytes: 2.6" "Group enriched" "Detected in many" 5 "breast cancer: 23.7;liver cancer: 10.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53 "memory B-cell: 21.5;naive B-cell: 8.0" "Lineage enriched" "Detected in single" 76 "B-cells: 21.5" "Cell line enhanced" "Detected in some" "RT4: 4.0;SCLC-21H: 8.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018241 Enhanced "Secreted to extracellular matrix" NA NA 22000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA018241: AB_1846612" "prognostic favorable (7.68e-4)" "unprognostic (4.34e-2)" "unprognostic (1.24e-1)" "unprognostic (9.67e-3)" "unprognostic (1.92e-1)" "unprognostic (3.06e-3)" "prognostic favorable (1.59e-4)" "unprognostic (1.51e-2)" "unprognostic (4.75e-2)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-2)" "unprognostic (1.51e-3)" "unprognostic (1.41e-3)" 2.1 14.1 6.2 0.7 7.9 0.3 9.6 17.4 7.3 21.8 3.9 6.7 7.6 0.5 0.1 1.8 0.8 1.5 1.7 5.5 6.3 2.4 36.2 1.6 0.6 5.6 4.9 3.1 32.6 0.0 1.3 0.5 5.7 1.9 4.0 0.5 21.3 0.2 14.5 8.5 10.3 0.1 5.1 1.1 10.8 1.2 5.8 0.2 4.2 0.9 0.2 1.2 1.6 5.4 1.0 0.8 0.7 0.6 0.0 0.0 2.1 0.1 0.0 0.0 0.0 1.5 0.8 0.1 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.6 0.7 1.2 0.7 1.5 0.0 0.4 1.1 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.1 0.3 0.0 0.5 0.0 0.7 0.1 0.1 0.7 0.9 0.1 1.5 0.0 4.0 8.5 0.2 0.1 0.3 0.0 0.3 0.3 0.2 0.9 2.1 0.4 0.1 0.0 1.4 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 0.2 0.0 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 6.2 7.9 17.4 7.3 5.5 6.3 5.6 4.9 5.7 5.1 5.8 5.4 0.0 0.0 0.0 1.3 1.0 0.3 0.2 0.3 0.0 0.0 4.6 2.4 0.2 1.5 0.2 0.0 0.0 0.1 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.2 4.3 0.0 0.3 0.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 5.5 0.1 0.0 2.5 0.0 1.1 0.2 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.4 CHADL SLRR4B ENSG00000100399 "Chondroadherin like" Q6NUI6 22 41229510-41240931 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 109.6" "Cell type enhanced" "Detected in many" "Muller glia cells: 40.3;Oligodendrocytes: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 11.8;Hep G2: 3.4;hTCEpi: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005696, HPA024654" Uncertain "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "HPA005696: AB_1079724, HPA024654: AB_1846615" "unprognostic (6.14e-2)" "unprognostic (4.42e-3)" "unprognostic (1.49e-1)" "unprognostic (6.45e-3)" "unprognostic (1.32e-1)" "unprognostic (9.51e-3)" "unprognostic (2.20e-2)" "prognostic favorable (1.56e-4)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (2.83e-3)" "unprognostic (1.51e-2)" "unprognostic (4.67e-8)" "unprognostic (8.36e-3)" "unprognostic (4.10e-1)" "unprognostic (3.40e-1)" "unprognostic (4.09e-2)" 2.6 4.7 25.4 0.5 62.4 1.0 2.6 57.5 43.9 3.5 5.2 12.4 1.5 1.3 1.5 4.2 2.2 2.7 16.5 25.1 32.4 2.1 3.1 2.1 0.8 69.6 51.8 2.6 3.5 0.5 4.3 0.6 61.3 6.5 0.3 1.0 11.3 3.8 2.2 6.1 3.4 0.8 43.4 0.7 5.0 3.5 56.3 1.7 4.4 1.6 0.4 2.9 3.6 109.6 0.6 0.2 0.2 0.3 0.1 0.1 11.8 0.4 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.6 0.1 0.5 0.0 0.6 0.0 0.1 0.2 0.0 0.3 3.4 0.4 0.1 0.1 1.0 3.4 0.3 0.0 0.1 0.4 0.2 0.0 0.5 0.0 0.3 0.2 0.6 0.3 0.3 0.4 0.1 0.5 0.2 0.2 0.3 0.7 0.1 1.3 0.2 0.1 0.0 0.0 1.2 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.1 1.6 0.0 0.1 0.4 0.1 0.4 0.2 0.0 0.1 0.2 0.1 0.0 0.4 0.1 0.2 0.0 0.0 1.2 0.0 0.3 25.4 62.4 57.5 43.9 25.1 32.4 69.6 51.8 61.3 43.4 56.3 109.6 2.7 6.4 2.2 8.1 0.2 4.0 10.2 1.8 17.6 1.4 7.3 6.5 3.5 2.8 1.7 3.7 0.0 3.0 0.4 0.8 7.9 2.0 18.6 2.5 0.6 1.3 3.0 0.0 2.8 1.2 6.4 5.5 2.6 1.6 0.0 3.2 2.5 2.5 5.1 0.0 2.5 0.8 2.0 0.8 2.1 12.0 3.7 3.4 17.8 1.9 0.4 40.3 0.0 12.5 83.1 0.8 1.0 3.0 0.3 3.7 1.3 5.9 4.1 1.6 0.0 2.5 1.2 0.3 0.8 6.5 3.7 1.5 0.5 0.7 1.4 6.5 CHCHD10 "C22orf16, MIX17A, N27C7-4" ENSG00000250479 "Coiled-coil-helix-coiled-coil-helix domain containing 10" Q8WYQ3 22 23765834-23767972 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1622.6;skeletal muscle: 1220.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1264.7;Distal tubular cells: 2498.5;Hepatocytes: 1879.9;Proximal enterocytes: 1501.3;Proximal tubular cells: 1437.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003440 Enhanced Supported Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003440: AB_1078348" "unprognostic (3.88e-2)" "unprognostic (2.36e-3)" "unprognostic (8.90e-2)" "unprognostic (9.80e-2)" "unprognostic (7.68e-2)" "unprognostic (5.97e-3)" "unprognostic (1.59e-1)" "unprognostic (1.85e-1)" "unprognostic (2.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.61e-1)" "unprognostic (5.13e-2)" "prognostic favorable (2.15e-7)" "unprognostic (5.19e-3)" "unprognostic (2.06e-1)" "unprognostic (5.68e-3)" "unprognostic (2.62e-3)" 216.5 136.5 181.6 30.3 188.3 12.5 144.5 183.0 248.9 77.3 262.6 261.2 92.6 35.5 32.4 147.3 43.1 10.9 1622.6 176.6 190.5 409.5 789.7 56.9 28.6 182.2 182.2 29.0 118.0 220.0 112.3 11.9 187.6 106.4 76.2 63.1 148.3 50.5 1220.9 71.8 159.0 17.9 169.5 100.3 160.2 27.8 204.8 14.0 224.7 660.7 34.5 110.2 89.1 179.3 33.1 66.4 19.7 85.9 42.1 27.7 41.9 11.9 22.8 23.5 28.4 124.1 35.1 113.5 30.7 41.2 12.9 99.8 109.2 34.1 20.5 35.9 140.6 22.5 48.8 117.1 73.8 63.6 108.2 53.3 91.9 35.6 9.3 4.9 29.0 17.2 47.7 48.0 20.6 121.8 21.8 48.2 16.9 194.9 183.5 90.0 4.0 209.0 112.7 55.3 41.3 23.8 13.9 145.7 149.7 36.6 54.9 47.0 15.3 1.0 1.1 18.3 0.2 28.8 11.1 62.5 20.5 54.9 11.2 0.2 4.1 11.2 3.0 9.1 1.9 11.7 3.2 4.0 1.8 10.6 4.9 3.5 0.0 0.8 8.2 7.3 4.3 1.2 181.6 188.3 183.0 248.9 176.6 190.5 182.2 182.2 187.6 169.5 204.8 179.3 88.7 12.8 10.5 36.2 294.8 48.2 415.4 28.2 144.5 136.2 156.9 238.2 503.8 268.8 20.5 419.3 114.7 42.5 104.7 1264.7 2498.5 88.1 27.0 76.6 229.8 47.4 310.5 74.3 38.5 54.5 255.7 67.8 300.7 94.3 84.0 171.9 78.1 1879.9 647.5 99.3 37.6 860.9 26.4 262.1 127.5 18.0 48.7 243.1 373.5 15.9 107.8 188.5 25.7 17.1 17.4 45.9 890.1 29.3 297.3 192.4 1501.3 1437.4 10.0 287.8 124.9 254.0 200.4 32.3 43.4 459.3 43.9 105.2 123.0 216.0 952.4 470.1 CHD3 "Mi-2a, Mi2-ALPHA, ZFH" ENSG00000170004 "Chromodomain helicase DNA binding protein 3" Q12873 17 7884796-7912760 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043368, HPA076524" Supported Supported "Nucleoplasm,Nucleoli,Centriolar satellite" No No "Cluster 27: Non-specific - Gene expression" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "Centriolar satellite" "HPA043368: AB_2678448, HPA076524: AB_2686804" "unprognostic (1.77e-2)" "unprognostic (8.01e-2)" "prognostic unfavorable (2.43e-4)" "prognostic favorable (7.68e-5)" "unprognostic (1.53e-1)" "unprognostic (8.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.11e-1)" "unprognostic (2.83e-2)" "unprognostic (5.25e-3)" "prognostic favorable (8.36e-4)" "unprognostic (9.11e-2)" "unprognostic (8.31e-2)" "unprognostic (3.98e-2)" "unprognostic (1.50e-1)" "unprognostic (8.90e-3)" "unprognostic (2.20e-3)" 28.2 29.3 19.9 35.0 27.9 42.7 28.4 0.0 39.9 71.6 0.0 55.3 16.7 63.9 31.2 35.1 56.8 27.8 21.2 35.8 7.0 38.3 5.7 32.4 41.3 4.9 2.4 60.0 34.8 44.7 47.7 16.6 1.1 68.7 22.1 19.0 40.3 38.0 8.0 32.7 34.6 45.0 3.1 31.5 36.3 20.9 8.0 58.2 44.9 9.1 36.7 41.2 42.8 21.4 44.9 108.7 61.6 81.2 72.2 60.9 32.8 51.7 66.1 40.8 43.5 21.1 36.7 122.8 38.3 73.0 34.0 59.6 117.7 52.5 53.0 65.5 67.2 62.7 148.5 2.7 38.3 17.8 112.1 79.2 27.5 55.4 36.9 108.7 76.9 54.1 41.5 2.0 38.8 42.6 48.2 19.6 9.8 45.3 40.3 137.8 82.1 19.3 40.0 107.7 41.9 56.3 126.4 47.9 24.6 16.9 55.7 27.1 99.7 89.4 68.8 22.3 72.5 8.8 1.6 68.3 46.1 47.4 77.6 1.7 2.6 3.3 4.1 1.4 3.6 1.1 4.2 4.0 1.3 1.2 4.6 3.1 2.8 3.2 3.2 3.0 2.5 2.5 19.9 27.9 0.0 39.9 35.8 7.0 4.9 2.4 1.1 3.1 8.0 21.4 20.9 32.1 63.2 10.4 19.6 36.6 47.6 21.1 65.4 60.7 43.8 34.2 14.3 17.2 35.2 80.9 8.4 16.8 57.3 39.8 17.6 22.9 11.3 48.6 51.9 29.4 56.8 19.1 20.6 23.4 20.5 39.9 31.1 70.7 39.9 59.7 22.9 2.7 9.0 45.4 25.2 17.0 12.2 24.7 34.7 18.5 44.4 26.7 8.8 6.5 43.7 12.4 59.8 12.1 2.5 20.9 10.8 57.2 17.4 55.5 10.9 9.7 24.8 17.3 26.3 31.8 43.5 25.5 46.8 52.8 20.5 16.4 62.9 52.0 30.3 60.3 CHD8 "DUPLIN, HELSNF1, KIAA1564" ENSG00000100888 "Chromodomain helicase DNA binding protein 8" Q9HCK8 14 21385194-21456126 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052186, HPA076133" Enhanced Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA052186: AB_2681754, HPA076133: " "unprognostic (3.45e-1)" "unprognostic (9.71e-2)" "unprognostic (3.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.14e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.31e-2)" "unprognostic (9.22e-2)" "prognostic favorable (8.35e-4)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (2.54e-3)" "unprognostic (2.88e-1)" "unprognostic (9.24e-2)" "unprognostic (2.51e-1)" "unprognostic (8.07e-3)" 12.5 11.9 11.2 13.5 12.5 35.3 14.8 16.3 13.2 12.4 10.5 14.0 9.4 14.8 11.1 14.9 12.9 10.1 12.0 11.1 12.2 11.7 9.6 13.7 18.0 11.4 11.6 17.1 13.6 22.3 13.1 11.7 11.1 13.2 12.3 14.8 13.6 12.1 15.7 22.3 14.7 14.8 11.5 15.8 14.2 12.9 12.5 25.4 14.8 12.7 17.5 12.8 12.9 13.6 31.2 39.6 43.6 20.7 27.7 23.6 24.9 24.4 28.4 36.5 35.4 35.0 26.3 51.4 14.8 33.1 28.4 37.2 54.9 35.1 46.0 39.3 24.2 46.3 27.6 43.5 25.7 64.6 40.4 32.8 27.2 40.9 29.7 28.6 33.4 40.2 32.4 26.7 28.0 33.9 46.1 26.0 33.4 30.9 34.3 42.0 32.9 17.4 27.3 57.9 30.9 30.7 37.5 29.8 21.8 39.7 20.7 30.5 36.4 29.2 23.0 17.8 29.1 30.3 38.4 50.3 12.1 23.2 29.6 9.1 3.8 9.8 5.5 3.8 6.4 4.2 4.9 5.6 2.7 11.2 5.0 4.4 7.9 7.8 6.7 6.1 4.7 2.7 11.2 12.5 16.3 13.2 11.1 12.2 11.4 11.6 11.1 11.5 12.5 13.6 27.6 38.5 56.3 27.4 32.2 12.6 11.3 15.9 23.3 33.3 21.9 22.6 19.6 24.3 32.6 33.1 27.1 14.7 40.0 16.8 1.9 21.8 3.4 32.5 37.9 25.5 27.1 27.8 41.0 23.6 12.3 24.0 27.5 39.5 28.4 41.7 13.9 14.9 17.5 23.5 40.2 16.0 8.2 20.1 9.3 4.1 16.1 25.3 10.6 20.6 27.1 18.9 32.0 29.7 33.1 26.5 13.9 17.7 32.4 16.1 12.0 7.4 28.8 24.3 0.0 32.1 26.2 29.2 25.1 24.6 16.6 12.3 31.4 34.1 16.8 12.7 CHGA ENSG00000100604 "Chromogranin A" P10645 14 92923150-92935285 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 6568.4" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 6553.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 114.8" "Group enriched" "Detected in many" 16 "cerebral cortex: 326.0;white matter: 124.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 151 "SCLC-21H: 489.5;SH-SY5Y: 1339.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000023, HPA017369, CAB040544, CAB055506, CAB058688" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 295000000 100000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB000023: , CAB040544: , CAB055506: AB_2081135, CAB058688: AB_2665574, HPA017369: AB_1846698" "prognostic favorable (7.85e-5)" "unprognostic (4.89e-2)" "unprognostic (5.96e-2)" "unprognostic (1.17e-1)" "unprognostic (1.43e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (4.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (1.85e-1)" "unprognostic (8.81e-13)" "unprognostic (1.07e-2)" "unprognostic (1.77e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (3.99e-4)" 14.5 1248.5 8.6 9.4 11.4 0.2 0.3 0.0 326.0 8.3 0.0 92.0 242.7 0.4 0.3 1.0 1.1 0.2 0.2 4.4 1.7 1.0 0.4 1.6 0.1 14.4 0.0 0.2 102.5 6568.4 446.2 0.0 4.1 12.2 105.2 11.0 0.2 0.3 0.1 0.6 179.9 0.9 0.0 0.1 364.5 77.7 4.3 0.6 24.6 0.0 0.0 1.3 1.2 124.4 0.0 0.5 2.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.8 2.7 0.0 0.0 0.2 0.0 1.4 0.0 0.0 489.5 1339.4 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 4.2 0.3 0.4 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 11.4 0.0 326.0 4.4 1.7 14.4 0.0 4.1 0.0 4.3 124.4 0.1 0.0 0.0 11.1 1.0 0.9 0.4 0.0 0.0 17.3 0.2 0.3 2.9 0.0 0.0 0.0 29.2 0.3 0.0 9.8 0.0 0.1 1.3 6.0 2.3 0.8 6553.1 0.0 59.5 0.4 0.1 4.1 195.7 0.5 0.0 0.5 0.0 0.0 1.5 16.8 37.7 820.4 14.2 0.0 0.0 7.9 39.7 0.1 7.2 15.9 2.0 3.7 0.0 10.6 12.8 46.5 137.8 137.3 0.0 6.6 36.7 0.0 0.0 16.2 0.0 0.0 0.2 4.7 2.2 0.0 0.0 0.3 0.2 0.4 25.9 5.1 CHGB "SCG1, SgI" ENSG00000089199 "Chromogranin B" P05060 20 5911510-5925353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "adrenal gland: 3466.0;pituitary gland: 1425.3" "Cell type enriched" "Detected in many" 5 "Enteroendocrine cells: 1036.1" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 154.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "SCLC-21H: 355.0;SH-SY5Y: 541.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008759, CAB009403, HPA012602" Enhanced Supported Enhanced Vesicles "Intracellular and membrane" NA NA 6500000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB009403: AB_2081255, HPA008759: AB_1846704, HPA012602: AB_1846706" "unprognostic (1.79e-3)" "unprognostic (7.72e-2)" "unprognostic (3.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (7.96e-3)" "unprognostic (2.86e-1)" "unprognostic (6.18e-3)" "unprognostic (7.93e-2)" "prognostic favorable (9.96e-4)" "unprognostic (8.56e-2)" "unprognostic (8.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" 27.5 3466.0 17.1 5.3 9.9 0.8 2.1 134.2 90.9 0.6 0.0 7.9 60.2 1.6 4.2 0.6 13.7 0.4 71.9 101.9 92.2 8.3 0.7 2.4 3.1 76.5 100.2 25.8 92.8 6.4 1425.3 0.7 188.4 5.3 14.2 56.9 6.1 3.8 11.0 1.7 31.6 0.9 12.8 0.3 133.3 14.9 19.3 4.0 9.7 0.8 1.4 0.4 2.3 14.2 0.0 7.9 0.9 0.0 0.2 0.2 0.4 0.2 0.0 0.1 0.0 1.9 0.0 0.0 4.3 0.0 4.9 0.1 0.0 0.1 0.1 0.6 0.1 2.6 0.0 1.6 0.1 4.2 0.2 1.5 0.0 0.0 2.1 0.1 0.1 0.2 0.4 0.1 1.0 0.0 0.1 0.9 19.7 1.3 0.0 0.1 0.0 0.4 0.5 0.2 355.0 541.8 0.0 0.5 0.4 2.1 0.3 0.4 0.3 0.1 6.4 0.4 3.3 0.0 0.7 2.7 0.5 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.1 9.9 134.2 90.9 101.9 92.2 76.5 100.2 188.4 12.8 19.3 14.2 0.0 3.2 2.4 7.5 0.3 4.2 9.9 0.8 0.0 93.3 0.1 0.3 114.4 0.0 0.7 69.9 20.9 0.1 0.0 1.6 1.9 0.5 7.1 0.2 0.7 3.0 1036.1 0.0 31.6 0.4 0.0 18.9 4.1 0.3 0.0 202.8 0.0 0.3 0.1 75.7 28.8 61.9 65.1 0.3 9.5 8.3 0.9 1.6 7.2 9.4 1.1 13.7 1.0 7.5 5.2 22.9 17.7 0.4 0.0 3.3 3.2 0.3 4.4 75.6 13.1 3.0 1.6 76.6 41.8 0.0 3.7 0.3 1.0 3.0 2.2 4.2 CHI3L1 "GP39, YK-40, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186704 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 232.4;brain: 239.4;liver: 447.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 88.7;Ductal cells: 88.9;Hepatocytes: 61.8;Hofbauer cells: 317.5" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 495 "neutrophil: 470.4" "Lineage enriched" "Detected in single" 495 "granulocytes: 470.4" "Cell line enhanced" "Detected in some" "ASC diff: 322.9;ASC TERT1: 712.9;HSkMC: 637.0;THP-1: 1068.4;U-138 MG: 303.5;U-87 MG: 303.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 10 "olfactory bulb: 16.0" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 25100000 180000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" 79.8 2.0 58.9 138.9 75.9 232.4 62.8 55.3 94.7 30.5 56.8 6.5 0.4 19.5 1.0 14.4 23.4 3.0 9.8 47.4 129.6 60.9 447.8 38.4 32.4 239.4 112.8 6.6 13.8 0.2 134.5 10.1 135.6 13.7 2.0 50.9 99.4 0.9 21.0 75.6 16.8 6.8 70.0 13.9 9.7 1.0 156.4 12.4 15.0 1.0 36.9 97.8 9.1 70.8 0.8 0.0 0.0 0.3 322.9 712.9 0.0 0.0 0.2 0.0 0.0 75.3 0.2 0.1 1.2 0.4 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 8.3 0.3 0.3 637.0 0.0 1.9 0.3 30.8 0.0 0.0 0.0 1.0 0.2 0.3 0.0 5.8 2.7 0.0 0.0 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.3 0.5 0.4 0.2 0.0 1068.4 0.0 303.5 1.6 0.0 0.4 2.3 41.9 0.3 303.7 1.2 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 470.4 0.0 0.9 0.0 0.0 1.3 58.9 75.9 55.3 94.7 47.4 129.6 239.4 112.8 135.6 70.0 156.4 70.8 0.7 6.4 42.8 20.5 0.1 4.2 47.1 88.7 0.0 0.1 29.8 21.5 1.0 2.8 17.3 27.6 0.0 1.3 0.6 0.0 0.0 88.9 0.0 4.8 2.2 2.1 0.0 0.4 1.1 0.0 1.1 18.6 0.0 7.2 0.0 0.0 0.0 61.8 317.5 0.0 0.1 0.0 6.1 0.8 0.4 0.0 0.9 23.7 14.2 0.0 1.0 45.1 0.0 0.0 0.1 2.0 0.0 0.0 1.4 4.2 0.0 0.2 3.4 2.8 0.0 1.0 2.3 0.0 0.0 1.5 1.1 0.8 0.9 0.0 0.0 2.2 CHI3L2 "YKL-39, YKL39" ENSG00000064886 "Chitinase 3 like 2" Q15782 1 111200771-111243440 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 200.6;salivary gland: 142.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 118.1;B-cells: 76.4;Breast glandular cells: 32.2;Breast myoepithelial cells: 30.4;Leydig cells: 74.9" "Cancer enriched" "Detected in many" 8 "glioma: 104.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 91.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "JURKAT: 634.6;MOLT-4: 346.8" "Low region specificity" "Detected in all" HPA005443 Approved "Secreted to blood" NA NA 420000 "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA005443: AB_1078510" "unprognostic (1.02e-2)" "unprognostic (4.34e-2)" "unprognostic (1.37e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (9.10e-5)" "prognostic favorable (2.19e-4)" "unprognostic (7.12e-2)" "unprognostic (1.39e-1)" "unprognostic (1.49e-3)" "unprognostic (1.26e-2)" "unprognostic (1.32e-2)" "unprognostic (2.44e-2)" "prognostic unfavorable (8.59e-7)" "unprognostic (7.15e-3)" "unprognostic (7.68e-2)" "unprognostic (1.39e-3)" "unprognostic (1.20e-1)" 22.1 3.0 12.4 112.7 12.0 2.4 44.6 9.2 41.6 1.0 10.9 3.2 1.2 1.7 0.2 5.1 2.2 11.8 23.0 12.3 13.6 3.1 0.9 66.1 59.8 63.7 34.7 2.1 0.8 36.6 4.5 13.7 27.1 7.4 2.6 1.7 142.1 0.7 2.0 11.3 10.0 3.7 18.6 21.5 5.9 11.7 34.5 200.6 11.8 7.5 119.0 53.5 4.5 26.4 0.3 0.0 0.4 0.5 100.3 19.1 0.2 0.1 1.3 0.2 0.2 0.0 0.3 0.8 0.2 0.1 8.8 0.6 3.5 0.2 0.1 29.0 0.1 0.2 0.5 1.6 1.5 0.2 1.7 27.9 0.3 0.4 0.5 5.5 0.0 634.6 0.2 1.2 0.3 0.2 346.8 0.5 0.0 0.1 0.1 1.8 0.9 0.6 0.0 0.7 0.1 0.3 0.4 0.9 0.3 2.1 0.3 0.3 0.5 7.5 1.4 0.2 0.7 5.2 0.6 76.8 23.4 0.5 2.3 1.0 3.6 0.2 22.4 0.8 5.5 45.0 16.0 37.5 0.8 43.2 91.6 34.4 2.2 17.2 0.3 1.4 10.8 27.3 12.4 12.0 9.2 41.6 12.3 13.6 63.7 34.7 27.1 18.6 34.5 26.4 0.5 9.6 118.1 1.0 76.4 2.3 1.6 8.3 0.0 0.1 32.2 30.4 0.5 0.0 3.1 0.0 0.0 0.2 7.8 0.1 0.0 20.1 3.8 0.3 7.0 0.9 1.2 0.0 0.2 0.4 0.9 10.8 0.0 0.7 2.5 0.0 0.4 0.0 1.1 0.0 0.1 0.0 0.0 2.2 0.7 12.0 74.9 2.2 16.0 0.0 0.8 0.0 23.7 0.0 0.3 0.9 0.0 1.5 2.6 3.5 0.0 0.5 0.2 0.0 0.0 1.8 0.7 0.5 0.6 0.3 1.3 3.1 12.8 1.5 0.0 1.3 CHIA "AMCase, CHIT2, TSA1902" ENSG00000134216 "Chitinase acidic" Q9BZP6 1 111290851-111320566 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Carbohydrate metabolism, Chitin degradation, Immunity, Inflammatory response, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "stomach 1: 327.5" "Cell type enriched" "Detected in some" 5 "Alveolar cells type 2: 34.6" "Group enriched" "Detected in some" 4 "lung cancer: 1.8;stomach cancer: 2.0;thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "ASC diff: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA059193 Approved "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 4: Stomach - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA059193: AB_2683942" "unprognostic (8.00e-2)" "unprognostic (7.08e-2)" "unprognostic (2.02e-2)" "unprognostic (4.99e-2)" "unprognostic (7.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" 0.3 0.2 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.6 0.5 1.6 0.3 0.0 0.1 0.1 0.1 0.1 0.2 10.6 0.3 0.2 0.1 0.1 0.2 2.0 1.9 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.1 0.0 327.5 0.5 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 34.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 CHID1 "FLJ42707, MGC3234, SI-CLP" ENSG00000177830 "Chitinase domain containing 1" Q9BWS9 11 867859-915058 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 404.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039374 Uncertain Uncertain "Nucleoplasm,Intermediate filaments" "Intracellular and membrane" No No 1500000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Intermediate filaments" "HPA039374: AB_10673609" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (8.96e-2)" "prognostic favorable (6.76e-4)" "unprognostic (4.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.97e-2)" "unprognostic (3.62e-2)" "unprognostic (7.88e-2)" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" "unprognostic (5.21e-2)" "unprognostic (1.74e-3)" "unprognostic (1.15e-1)" "unprognostic (7.53e-2)" "unprognostic (3.29e-2)" "unprognostic (2.89e-2)" 43.9 63.3 43.1 22.7 44.1 46.2 40.2 41.0 51.7 44.5 60.0 34.2 30.9 38.0 89.5 34.8 63.5 41.3 54.4 44.1 47.2 52.5 85.8 30.9 27.2 42.9 42.9 58.0 149.9 46.1 62.8 42.7 42.5 42.3 29.7 25.2 82.2 41.3 37.0 34.9 27.7 35.7 42.6 71.6 47.1 74.1 45.7 20.1 47.3 31.1 20.2 34.3 35.3 47.0 75.6 71.7 53.2 131.6 203.3 107.5 90.1 83.2 97.0 78.8 76.7 78.7 214.6 61.1 75.1 121.7 78.4 145.2 53.1 95.9 57.3 53.7 131.9 44.1 25.9 75.1 92.6 102.9 37.4 104.1 59.2 53.9 77.2 130.3 67.2 76.6 81.2 152.6 55.8 52.9 58.4 134.0 47.2 141.6 107.3 49.0 50.9 111.8 57.5 21.5 101.8 84.5 90.3 124.0 78.4 53.0 50.4 156.8 66.6 89.6 38.9 25.3 68.3 88.9 81.4 36.0 100.2 88.6 71.7 21.1 50.4 19.2 34.7 45.0 37.1 45.7 33.2 36.8 74.0 32.1 34.9 35.3 6.2 43.4 45.6 69.6 32.4 46.0 43.1 44.1 41.0 51.7 44.1 47.2 42.9 42.9 42.5 42.6 45.7 47.0 33.0 41.7 36.7 4.2 28.6 22.8 62.2 78.9 22.2 38.5 69.9 75.7 25.6 51.5 49.0 53.3 18.8 121.3 34.4 25.2 72.4 62.3 120.9 44.0 44.4 31.5 53.3 56.4 7.8 58.3 79.7 69.6 20.9 36.8 29.2 107.6 50.0 91.2 81.1 30.3 7.8 42.8 57.0 66.6 24.7 404.8 62.7 34.0 55.2 1.9 35.2 60.6 20.6 6.0 6.8 38.0 43.2 58.3 123.7 86.5 71.5 85.1 45.7 53.2 52.6 45.9 41.7 208.3 139.9 37.2 23.3 91.5 19.2 85.4 59.9 62.6 CHIT1 "CHI3, CHIT" ENSG00000133063 "Chitinase 1" Q13231 1 203212827-203273641 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.8;lung: 36.4;lymphoid tissue: 21.7" "Cell type enriched" "Detected in some" 10 "Hofbauer cells: 40.6" "Cancer enhanced" "Detected in many" "testis cancer: 31.9" "Region enriched" "Detected in some" 6 "cerebral cortex: 12.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010575, HPA074844" Enhanced "Secreted to blood" NA NA 26400000 57000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Macrophages - Innate immune response" "HPA010575: AB_1078512, HPA074844: " "unprognostic (5.80e-3)" "prognostic favorable (2.02e-4)" "unprognostic (2.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.87e-2)" "unprognostic (2.28e-2)" "unprognostic (7.55e-2)" "unprognostic (6.36e-3)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (1.56e-3)" "unprognostic (3.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" 13.6 0.3 0.2 0.4 0.2 49.8 8.3 0.0 12.4 8.1 0.0 1.2 0.0 3.6 0.1 0.0 0.1 0.4 0.2 0.2 0.0 0.1 0.7 36.4 21.7 0.4 0.2 0.5 2.1 0.0 0.0 0.7 1.3 1.0 1.0 0.0 0.4 0.0 0.2 0.4 0.8 0.0 0.4 5.7 0.5 0.0 0.3 3.4 1.3 0.0 1.1 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.2 0.2 0.0 12.4 0.2 0.0 0.4 0.2 1.3 0.4 0.3 2.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 0.0 0.0 0.2 0.3 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 40.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 CHKA "CHK, CKI" ENSG00000110721 "Choline kinase alpha" P35790 11 68052859-68121444 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 179.6;Early spermatids: 357.3;Late spermatids: 267.3;Oligodendrocytes: 203.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 183.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024153, CAB072803" Approved Approved "Endoplasmic reticulum" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "CAB072803: , HPA024153: AB_1846664" "unprognostic (5.16e-2)" "unprognostic (1.46e-1)" "unprognostic (2.52e-1)" "unprognostic (2.51e-1)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (7.75e-4)" "unprognostic (2.36e-3)" "unprognostic (1.66e-3)" "unprognostic (1.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.99e-1)" "unprognostic (5.97e-3)" "unprognostic (5.00e-2)" "unprognostic (6.06e-2)" "unprognostic (1.82e-1)" "unprognostic (4.73e-2)" 17.0 35.8 49.4 7.1 54.2 33.8 20.9 51.8 57.8 18.3 53.5 25.8 21.6 12.2 20.5 6.2 13.2 10.3 14.5 49.5 50.7 23.9 43.3 17.8 9.0 56.6 53.6 20.1 38.0 8.0 21.6 5.2 61.5 31.0 12.8 21.1 44.9 16.4 8.3 8.7 23.1 5.4 51.0 30.0 40.0 75.5 54.0 5.7 43.6 4.5 5.5 19.4 9.3 71.7 25.6 21.3 24.2 24.1 8.0 6.1 24.5 7.7 13.6 22.5 14.4 92.2 70.5 18.9 27.4 12.4 23.2 16.2 34.4 5.6 18.5 8.7 12.1 23.8 29.6 106.9 22.9 25.6 12.5 11.0 9.4 10.0 4.8 12.3 12.7 11.9 23.1 34.7 12.0 19.4 14.6 68.4 40.1 83.2 14.2 21.3 26.1 54.6 18.1 27.3 17.9 19.6 14.9 74.6 183.8 19.9 31.6 34.4 7.3 14.2 16.3 32.4 10.4 37.0 42.5 34.4 14.6 32.8 13.0 0.0 0.8 6.1 0.1 1.5 0.0 0.7 0.1 0.2 0.9 0.3 0.4 0.2 0.4 1.1 0.9 0.7 0.2 0.2 49.4 54.2 51.8 57.8 49.5 50.7 56.6 53.6 61.5 51.0 54.0 71.7 27.2 44.8 36.6 179.6 10.1 15.8 16.6 6.5 18.2 10.6 49.4 35.7 3.6 35.8 20.2 3.7 33.3 8.2 14.2 48.1 13.7 9.6 357.3 42.7 16.2 13.6 28.1 6.7 89.0 19.3 3.4 9.2 37.2 59.0 19.0 23.4 11.7 19.8 17.6 57.2 63.2 16.3 0.0 28.5 19.4 267.3 6.2 31.0 23.2 59.0 8.5 21.4 2.1 100.0 203.5 18.4 18.0 2.6 10.1 17.3 21.6 4.6 23.1 28.4 0.0 9.6 9.8 121.9 20.7 9.2 10.4 13.0 8.2 16.9 31.7 39.2 CHL1 "CALL, FLJ44930, L1CAM2, MGC132578" ENSG00000134121 "Cell adhesion molecule L1 like" O00533 3 196763-409417 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8" "Cell type enhanced" "Detected in many" "Astrocytes: 223.6;Excitatory neurons: 423.8;Inhibitory neurons: 320.7;Oligodendrocyte precursor cells: 918.4" "Cancer enhanced" "Detected in many" "glioma: 15.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 33 "memory B-cell: 2.7;naive B-cell: 3.7" "Lineage enriched" "Detected in single" 38 "B-cells: 3.7" "Group enriched" "Detected in some" 5 "SK-MEL-30: 91.8;WM-115: 29.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003345, CAB026120" Enhanced "Secreted in brain" NA NA 5800000000 "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB026120: , HPA003345: AB_1078516" "unprognostic (5.54e-2)" "unprognostic (2.08e-1)" "unprognostic (7.45e-2)" "unprognostic (7.14e-3)" "unprognostic (1.16e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-2)" "unprognostic (2.22e-1)" "unprognostic (5.14e-1)" "unprognostic (1.06e-1)" "unprognostic (7.81e-2)" "unprognostic (3.51e-1)" "prognostic favorable (1.21e-6)" "unprognostic (1.11e-1)" "unprognostic (6.07e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" 13.6 4.1 18.6 8.6 33.9 0.3 8.5 2.3 35.5 3.3 0.0 14.7 4.4 3.4 1.6 8.9 2.6 4.8 11.5 35.8 26.7 17.8 0.8 5.1 6.2 12.5 5.3 16.3 1.7 0.5 2.6 0.0 5.7 3.7 7.9 15.9 6.9 6.3 0.3 12.9 6.2 5.4 10.0 3.0 4.0 1.5 10.6 0.7 0.9 1.4 2.9 3.1 5.3 5.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 91.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 29.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 33.9 2.3 35.5 35.8 26.7 12.5 5.3 5.7 10.0 10.6 5.0 4.1 0.0 0.0 223.6 8.8 22.9 0.6 2.8 56.9 1.2 0.6 13.6 18.0 1.5 15.8 11.0 0.0 0.0 0.1 0.0 11.7 0.0 2.0 2.9 0.1 2.3 0.0 0.0 423.8 0.0 0.0 33.5 0.0 1.9 1.3 106.2 1.4 1.3 0.0 1.7 320.7 0.0 0.0 0.3 4.4 1.4 2.8 0.6 3.6 22.5 0.0 58.7 0.0 918.4 11.6 0.2 0.0 0.0 1.4 6.2 0.0 19.7 17.8 2.7 0.0 2.7 11.2 3.0 1.3 15.6 12.1 0.0 1.1 12.4 0.0 0.8 CHPF "CHSY2, CSS2" ENSG00000123989 "Chondroitin polymerizing factor" Q8IZ52 2 219538948-219543809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 163.7;Extravillous trophoblasts: 182.7;Syncytiotrophoblasts: 310.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035123 Approved Supported Vesicles,Centrosome,Cytosol "Intracellular and membrane" NA NA 570000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Vesicles, Centrosome" "HPA035123: AB_10602799" "unprognostic (1.13e-3)" "prognostic unfavorable (1.57e-4)" "unprognostic (3.65e-3)" "unprognostic (2.55e-3)" "unprognostic (1.86e-3)" "prognostic unfavorable (1.68e-4)" "unprognostic (1.37e-1)" "unprognostic (6.59e-3)" "unprognostic (7.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.18e-1)" "unprognostic (6.79e-2)" "unprognostic (1.64e-1)" "unprognostic (6.55e-2)" "unprognostic (1.82e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (2.96e-4)" 29.9 45.7 26.9 12.5 24.9 1.7 22.3 25.8 34.2 59.1 36.7 21.9 26.7 55.9 13.7 27.3 30.2 24.2 134.8 38.4 31.2 41.1 97.8 42.8 6.5 34.0 30.4 127.4 138.9 24.6 128.3 40.6 32.1 58.6 4.7 8.5 56.1 25.6 16.3 26.2 23.2 12.6 27.4 16.6 40.9 97.5 33.2 3.6 52.8 3.9 4.5 34.3 30.0 34.0 67.5 13.0 9.6 81.0 36.0 55.8 109.7 66.4 55.4 18.5 16.8 36.8 57.5 20.7 139.0 64.6 63.3 84.1 6.3 40.3 2.9 32.3 22.5 7.4 18.0 161.9 49.8 6.6 42.1 75.0 69.2 18.8 17.9 66.7 0.1 7.1 47.2 49.6 17.7 105.5 1.0 17.6 39.8 22.8 50.6 0.1 30.4 41.6 22.4 29.7 23.4 36.0 32.1 30.7 94.3 17.9 10.5 22.6 1.6 67.9 37.1 81.9 35.2 58.9 19.9 9.7 62.1 6.7 70.4 1.7 0.0 6.5 1.9 0.1 2.4 1.0 1.5 1.3 0.0 0.1 1.7 0.6 0.0 1.9 0.0 9.5 1.2 0.7 26.9 24.9 25.8 34.2 38.4 31.2 34.0 30.4 32.1 27.4 33.2 34.0 2.1 0.0 15.2 16.0 16.5 14.5 23.2 52.8 17.1 14.6 40.0 29.6 30.5 22.8 31.2 75.4 10.4 163.7 21.7 15.9 9.8 58.1 4.1 14.0 22.2 2.9 43.0 3.2 4.3 80.4 182.7 56.0 25.5 42.4 10.2 27.4 4.2 64.0 18.5 43.7 9.2 57.8 36.7 2.4 9.1 7.1 24.8 2.3 67.6 5.6 1.8 56.8 9.2 5.5 3.7 65.6 32.7 63.2 123.6 42.3 60.7 20.6 14.6 11.5 26.3 19.3 27.1 11.9 6.3 14.2 11.1 310.3 9.7 46.3 14.3 33.0 CHPF2 "ChSy-3, CSGlcA-T, KIAA1402" ENSG00000033100 "Chondroitin polymerizing factor 2" Q9P2E5 7 151232489-151238827 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020992 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Cytosol" "HPA020992: AB_1847267" "unprognostic (8.31e-2)" "unprognostic (2.14e-3)" "unprognostic (1.02e-3)" "unprognostic (1.14e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "prognostic unfavorable (9.47e-4)" "unprognostic (4.07e-1)" "unprognostic (1.71e-1)" "unprognostic (4.54e-2)" "prognostic favorable (2.51e-4)" "unprognostic (1.04e-1)" "unprognostic (2.68e-3)" "unprognostic (2.24e-1)" "unprognostic (1.49e-1)" "unprognostic (3.22e-2)" "unprognostic (8.59e-3)" 13.7 31.7 9.5 17.4 9.3 23.1 13.6 3.8 12.9 14.6 13.5 17.4 13.0 19.5 10.3 14.0 14.6 15.1 19.8 9.6 11.6 14.9 20.4 17.6 16.6 11.1 8.7 14.0 26.2 13.2 43.7 16.1 10.0 19.1 9.0 2.9 22.2 12.9 8.1 14.7 18.9 14.9 5.4 28.9 20.1 9.6 10.5 10.9 17.6 5.0 10.7 16.7 13.6 6.7 27.9 22.3 14.7 43.1 50.0 49.2 22.2 57.3 88.4 30.5 37.1 14.9 46.1 8.4 98.7 91.6 41.5 34.3 6.5 40.8 13.1 32.1 20.3 8.9 25.4 21.0 46.7 18.2 70.9 75.8 22.7 28.9 10.3 63.1 48.6 13.8 8.6 23.7 49.2 45.7 17.0 70.6 19.7 11.6 25.6 15.8 8.7 28.1 29.6 21.7 15.9 28.1 30.7 29.8 15.2 11.0 11.6 29.4 66.9 33.6 5.6 45.2 49.3 43.3 6.8 12.3 122.3 23.9 46.6 0.9 4.4 6.2 4.0 3.6 3.7 1.9 2.1 3.6 4.7 2.0 1.4 1.6 7.2 2.0 3.9 6.9 2.4 3.3 9.5 9.3 3.8 12.9 9.6 11.6 11.1 8.7 10.0 5.4 10.5 6.7 8.3 9.6 11.8 2.3 11.2 4.6 6.6 15.1 6.2 8.8 10.5 5.6 1.9 10.0 11.7 11.0 4.2 11.5 23.4 21.3 1.9 12.4 0.6 6.5 11.0 8.9 8.4 8.6 6.1 16.8 16.3 13.3 18.8 9.0 6.3 14.6 12.5 9.6 12.6 25.2 5.0 12.0 14.2 10.9 6.8 1.0 17.1 11.1 7.2 3.7 11.0 5.3 11.3 5.5 1.8 17.7 17.4 15.1 26.5 11.5 8.5 3.5 8.8 7.4 19.7 7.8 14.6 5.0 3.1 6.6 4.4 10.3 13.0 15.8 9.8 10.5 CHRD ENSG00000090539 Chordin Q9H2X0 3 184380073-184390736 "Plasma proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 130.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 31.2;Excitatory neurons: 28.2;Fibroblasts: 16.4;Hepatocytes: 36.4;Inhibitory neurons: 37.5;Skeletal myocytes: 19.1;Smooth muscle cells: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.8;Hep G2: 11.8;MCF7: 2.5;SuSa: 4.0;U-2 OS: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035827 Approved "Secreted in other tissues" NA NA 350000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 36: Stromal cells - Cell proliferation" "HPA035827: AB_10669657" "unprognostic (2.26e-1)" "unprognostic (3.25e-2)" "unprognostic (1.63e-2)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.12e-1)" "unprognostic (3.12e-2)" "unprognostic (6.55e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (5.53e-3)" "unprognostic (1.85e-1)" "unprognostic (9.84e-2)" "unprognostic (7.99e-3)" 11.1 12.2 13.9 2.1 13.9 0.0 9.9 19.0 21.2 40.0 9.1 7.6 1.6 32.9 3.2 3.3 15.0 2.5 11.2 15.1 9.4 18.8 130.0 7.2 1.5 10.1 9.9 16.3 17.1 1.1 6.0 2.4 10.2 9.7 0.8 0.0 3.8 5.2 4.4 5.4 6.0 4.6 10.3 9.7 7.8 1.1 9.7 0.2 7.7 2.7 0.3 7.2 15.4 13.6 0.0 0.0 0.3 1.1 0.1 0.1 1.4 0.3 0.0 0.2 0.1 2.8 0.0 0.0 1.1 0.3 1.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.0 11.8 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.0 0.0 0.0 0.6 0.0 0.1 0.1 0.1 4.0 1.4 0.0 0.0 0.0 3.8 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 13.9 19.0 21.2 15.1 9.4 10.1 9.9 10.2 10.3 9.7 13.6 2.6 0.0 0.0 11.8 0.4 2.7 0.0 0.0 0.6 2.9 2.1 1.8 3.1 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 3.6 31.2 2.6 0.0 0.0 28.2 3.1 0.0 16.4 1.1 4.5 0.0 0.9 3.3 36.4 0.7 0.0 37.5 0.2 0.0 3.2 3.1 0.0 3.7 0.4 1.8 4.7 0.0 0.0 0.0 7.1 2.5 1.1 0.0 2.2 0.0 0.1 0.0 4.0 0.0 0.5 6.6 19.1 16.4 0.3 0.3 0.3 1.1 0.1 0.7 0.1 0.0 0.3 CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Group enriched" "Detected in many" 4 "Astrocytes: 50.3;Fibroblasts: 83.8;Leydig cells: 41.0;Muller glia cells: 81.6" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "ASC diff: 537.8;ASC TERT1: 724.7;hTERT-RPE1: 341.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" 188.3 7.3 7.1 26.2 14.5 0.9 69.8 8.3 14.1 38.8 6.5 74.8 10.8 148.2 20.2 58.0 53.5 47.9 22.0 9.4 6.2 15.1 1.8 76.3 24.4 4.4 4.5 7.1 12.5 84.9 6.4 21.9 4.0 141.6 35.5 55.6 23.3 224.4 6.1 17.5 22.1 101.3 4.3 16.0 17.9 6.5 5.8 10.9 37.8 34.9 11.7 28.3 20.0 6.3 0.0 0.1 3.3 0.0 537.8 724.7 0.3 7.6 3.3 18.8 16.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.0 0.0 17.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 58.7 0.1 1.6 0.0 341.2 0.0 2.0 0.0 0.0 0.1 0.0 1.0 0.3 21.3 0.0 0.0 0.0 0.0 0.1 3.0 0.0 1.7 5.2 0.0 0.0 0.4 1.4 0.0 0.0 0.0 5.8 4.2 60.4 7.8 0.1 0.1 0.0 5.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.1 14.5 8.3 14.1 9.4 6.2 4.4 4.5 4.0 4.3 5.8 6.3 8.4 0.0 2.7 50.3 0.1 4.8 0.0 0.0 0.6 1.5 0.3 0.4 2.3 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 0.3 0.3 0.0 1.0 13.8 0.0 0.0 4.2 0.0 0.1 83.8 2.0 0.2 1.3 0.3 2.2 0.1 0.2 0.0 9.3 0.0 0.0 0.0 8.1 1.4 41.0 1.1 8.8 1.0 0.0 81.6 0.0 13.6 0.2 0.0 0.0 9.1 1.4 0.3 0.0 4.1 1.5 2.9 0.0 2.7 11.2 0.2 8.2 0.3 4.4 0.1 1.0 0.0 0.0 0.1 CHRDL2 BNF1 ENSG00000054938 "Chordin like 2" Q6WN34 11 74696429-74731426 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 145.1;gallbladder: 106.0;lymphoid tissue: 115.8;smooth muscle: 122.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 194.1;Hepatocytes: 112.2;Skeletal myocytes: 533.4" "Cancer enhanced" "Detected in many" "stomach cancer: 14.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.4;PC-3: 1.3;SiHa: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021771, HPA076522" Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 9700000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: HeLa - Mitochondria" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "HPA021771: AB_1846689, HPA076522: " "unprognostic (2.38e-2)" "unprognostic (1.80e-1)" "unprognostic (7.24e-2)" "unprognostic (3.41e-3)" "unprognostic (9.45e-2)" "unprognostic (2.09e-1)" "unprognostic (4.08e-2)" "unprognostic (4.33e-2)" "unprognostic (6.64e-2)" "unprognostic (2.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.23e-1)" "unprognostic (7.58e-6)" "unprognostic (8.39e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (6.08e-4)" 2.7 0.2 0.6 115.8 0.4 0.0 5.1 0.4 0.7 64.7 0.1 88.7 4.1 145.1 0.8 4.1 9.4 106.0 24.4 0.4 0.6 5.2 46.3 2.9 0.4 1.0 0.6 2.5 3.1 0.4 0.4 4.5 0.7 22.6 2.6 0.5 0.5 8.9 6.6 1.2 10.8 122.1 2.3 1.3 57.7 3.4 0.7 0.0 0.9 4.8 2.8 46.3 21.2 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.4 2.4 0.3 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.4 0.7 0.4 0.6 1.0 0.6 0.7 2.3 0.7 0.2 1.2 0.0 2.6 0.7 0.3 0.3 0.5 0.2 0.0 0.0 194.1 3.8 2.2 15.7 0.1 9.2 0.0 0.0 0.8 0.0 0.0 13.8 31.4 0.6 0.2 2.1 0.0 0.0 0.1 10.3 0.1 5.3 0.0 0.5 0.0 0.2 2.9 112.2 0.1 0.0 0.2 0.0 0.0 2.4 0.0 2.4 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.5 0.1 4.1 0.0 0.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 533.4 1.2 0.6 4.3 0.0 0.0 0.1 0.5 0.4 0.0 0.5 CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 72.1;prostate: 29.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.5;Inhibitory neurons: 14.8;Prostatic glandular cells: 2.4;Theca cells: 3.4" "Cancer enriched" "Detected in single" 421 "prostate cancer: 30.2" "Region enhanced" "Detected in many" "thalamus: 72.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (2.23e-2)" "unprognostic (3.19e-1)" "unprognostic (6.19e-2)" "unprognostic (6.29e-3)" "unprognostic (1.19e-2)" "unprognostic (2.13e-1)" "unprognostic (1.91e-1)" "unprognostic (7.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" 0.0 0.5 15.8 0.2 5.5 0.9 1.4 38.1 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.0 0.0 0.0 0.2 0.1 15.7 21.5 0.0 0.2 0.0 0.3 0.0 3.5 29.0 0.0 3.7 0.0 0.0 0.1 0.2 0.2 0.0 2.3 0.1 0.0 0.0 72.1 2.9 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 15.8 5.5 38.1 2.9 0.7 8.0 15.7 21.5 3.5 2.3 72.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 CHRNA4 "BFNC, EBN, EBN1" ENSG00000101204 "Cholinergic receptor nicotinic alpha 4 subunit" P43681 20 63343223-63378401 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 28.8;liver: 58.0" "Group enriched" "Detected in some" 4 "Hepatocytes: 42.0;Horizontal cells: 139.7" "Cancer enhanced" "Detected in some" "liver cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "U-2 OS: 2.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "midbrain: 21.8;pons: 20.5;thalamus: 33.5" CAB034064 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 9: U-2 OS - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "CAB034064: AB_2080535" "unprognostic (3.40e-1)" "unprognostic (1.71e-1)" "unprognostic (2.87e-2)" "unprognostic (3.98e-1)" "unprognostic (8.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.22e-1)" "unprognostic (1.74e-1)" "unprognostic (2.10e-3)" "unprognostic (5.72e-4)" "unprognostic (9.02e-3)" "unprognostic (9.79e-4)" "unprognostic (6.77e-2)" "unprognostic (1.08e-1)" "unprognostic (3.81e-2)" 0.0 0.2 6.7 0.0 6.5 0.0 0.0 0.6 6.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.7 8.7 3.4 58.0 0.0 0.0 5.7 15.7 0.1 0.0 12.7 0.8 0.0 6.2 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.0 1.6 28.8 0.0 0.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 6.5 0.6 6.2 6.7 8.7 5.7 15.7 6.2 0.5 28.8 4.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 22.4 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 4.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 42.0 0.0 139.7 8.8 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.9 0.0 7.5 2.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 2.7 0.0 1.7 0.1 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CHRNA5 ENSG00000169684 "Cholinergic receptor nicotinic alpha 5 subunit" P30532 15 78565520-78595269 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 13.0;Extravillous trophoblasts: 11.5;Intestinal goblet cells: 9.8;Spermatocytes: 12.4;Spermatogonia: 28.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA054381 Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Focal adhesion sites" "Plasma membrane" "HPA054381: AB_2682468" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" "unprognostic (3.20e-3)" "unprognostic (6.66e-2)" "unprognostic (1.29e-3)" "unprognostic (7.03e-5)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.34e-2)" "unprognostic (1.31e-2)" "unprognostic (4.52e-2)" "unprognostic (8.97e-2)" "unprognostic (6.50e-11)" "unprognostic (4.37e-1)" "unprognostic (5.39e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" 0.8 2.0 1.9 1.9 1.8 0.5 1.5 2.7 3.0 1.0 2.0 4.0 4.8 1.3 1.1 1.6 0.5 4.4 1.3 1.7 1.8 0.3 0.3 0.5 0.7 1.7 2.2 0.7 1.9 0.3 0.2 1.1 2.4 1.9 4.2 2.5 0.7 0.4 3.9 0.6 2.4 2.1 1.6 0.3 2.8 3.1 2.4 0.7 0.3 0.5 1.1 1.8 1.1 2.7 16.5 41.8 22.4 12.5 2.7 1.9 9.1 12.0 5.8 13.0 23.4 16.1 76.7 9.8 28.6 2.6 34.7 14.3 43.5 17.6 13.2 20.1 51.9 18.3 29.5 16.2 1.4 12.4 24.7 0.7 3.1 3.5 4.7 4.8 24.5 13.6 18.2 12.5 8.3 36.1 15.9 4.3 18.2 32.4 11.5 20.1 25.8 9.9 15.7 39.2 37.7 55.0 28.6 27.5 14.1 12.7 61.2 3.2 5.3 17.6 21.0 13.0 38.0 14.3 63.4 11.3 10.6 19.8 16.5 1.0 0.4 0.7 0.1 0.4 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.3 0.7 0.3 0.4 0.2 0.0 0.1 1.9 1.8 2.7 3.0 1.7 1.8 1.7 2.2 2.4 1.6 2.4 2.7 0.9 0.0 0.0 0.3 1.4 3.2 13.0 0.5 8.6 7.6 1.2 2.9 1.2 2.8 0.2 0.0 0.0 2.6 0.4 1.2 0.0 0.3 1.2 0.5 0.6 2.0 3.5 0.8 1.0 2.0 11.5 1.0 0.5 0.6 0.0 1.5 0.0 0.3 1.0 5.0 1.1 9.8 0.0 0.0 2.3 2.6 0.3 0.8 1.8 0.0 0.2 0.4 1.0 0.5 0.9 0.7 0.1 0.4 0.9 6.7 0.1 0.4 0.1 0.7 0.0 1.3 1.6 12.4 28.8 2.9 1.6 1.0 2.0 0.2 2.1 3.2 CHRNB1 CHRNB ENSG00000170175 "Cholinergic receptor nicotinic beta 1 subunit" P11230 17 7445061-7457710 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 158.4;tongue: 57.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 39.0;Skeletal myocytes: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 34.6;RH-30: 71.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005822, CAB011200" Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 47: Cytotrophoblasts - Unknown function" "CAB011200: AB_262151, HPA005822: AB_1079484" "unprognostic (2.89e-2)" "unprognostic (3.43e-1)" "unprognostic (1.08e-1)" "unprognostic (2.67e-2)" "unprognostic (4.19e-2)" "unprognostic (1.60e-1)" "unprognostic (1.84e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-2)" "unprognostic (3.56e-1)" "unprognostic (4.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.13e-2)" "unprognostic (6.91e-2)" "unprognostic (2.49e-1)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" 7.0 30.6 6.9 2.4 7.8 9.1 6.7 7.3 7.5 7.5 8.8 6.3 2.9 6.6 5.1 7.0 5.4 1.9 11.5 6.9 6.9 10.7 16.5 5.1 3.6 7.5 7.0 5.4 16.5 9.1 6.7 6.7 7.3 5.1 2.5 3.2 10.7 3.0 158.4 8.1 5.5 3.2 7.3 7.9 5.2 3.2 7.1 6.5 13.0 57.7 3.9 5.5 7.2 8.1 1.6 2.2 3.8 4.5 6.0 4.0 8.6 1.1 3.8 5.6 4.6 1.3 2.0 6.2 4.0 2.5 2.0 13.6 1.4 25.1 2.0 7.6 4.8 3.5 2.3 8.1 2.6 2.2 8.6 8.8 6.8 3.4 11.0 9.3 3.8 12.0 4.6 3.4 34.6 1.0 6.7 4.1 2.7 1.5 1.1 4.4 71.0 15.8 15.3 1.2 0.6 11.1 2.4 4.0 4.7 5.9 3.9 3.0 3.6 2.3 6.4 1.7 5.0 8.1 9.6 1.7 2.1 4.9 2.1 9.9 5.4 13.6 7.9 6.3 6.1 6.7 8.7 8.0 7.0 7.0 7.0 9.2 1.7 11.0 10.4 5.2 7.9 6.1 6.9 7.8 7.3 7.5 6.9 6.9 7.5 7.0 7.3 7.3 7.1 8.1 8.8 0.0 4.8 4.6 8.9 6.4 3.8 12.6 6.2 3.9 9.3 11.2 9.8 4.3 7.2 9.2 2.1 39.0 17.7 5.2 23.5 16.1 2.2 5.1 7.1 10.1 2.4 3.4 1.4 13.4 9.4 8.1 3.6 7.1 13.3 5.8 10.4 10.8 12.6 15.2 1.5 4.8 14.2 7.2 8.7 2.1 21.8 7.9 12.4 1.0 17.0 14.0 29.9 1.0 5.6 17.3 4.9 17.0 5.8 4.1 10.2 15.5 9.5 7.1 0.0 47.3 8.1 2.8 2.8 6.1 6.5 30.4 11.2 12.1 5.9 3.8 CHRND ACHRD ENSG00000135902 "Cholinergic receptor nicotinic delta subunit" Q07001 2 232525993-232536667 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skeletal muscle: 57.6" "Group enriched" "Detected in some" 10 "Muller glia cells: 4.0;Skeletal myocytes: 4.4" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 49 "RH-30: 99.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA056404, HPA065404" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA056404: AB_2732603, HPA065404: AB_2732734" "unprognostic (1.69e-2)" "unprognostic (7.93e-2)" "unprognostic (3.28e-3)" "unprognostic (7.75e-3)" "unprognostic (6.04e-2)" "unprognostic (1.10e-1)" "unprognostic (7.25e-2)" "unprognostic (1.90e-1)" "unprognostic (4.97e-8)" "unprognostic (7.52e-2)" "unprognostic (2.86e-1)" "unprognostic (2.46e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 6.3 0.7 0.0 57.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 99.4 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CHRNE ACHRE ENSG00000108556 "Cholinergic receptor nicotinic epsilon subunit" Q04844 17 4897771-4934438 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 55.3;pituitary gland: 27.6" "Cell type enriched" "Detected in many" 5 "Late spermatids: 161.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 9 "HEL: 5.0;HMC-1: 11.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "basal ganglia: 6.3" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.00e-3)" "unprognostic (1.56e-1)" "unprognostic (3.94e-2)" "unprognostic (4.35e-3)" "unprognostic (6.55e-2)" "unprognostic (2.27e-3)" "unprognostic (7.80e-4)" "unprognostic (7.75e-2)" "unprognostic (3.24e-1)" "unprognostic (1.34e-1)" "unprognostic (3.69e-2)" "unprognostic (6.58e-2)" "unprognostic (8.42e-4)" "unprognostic (1.39e-3)" "unprognostic (1.26e-1)" "unprognostic (5.83e-2)" "unprognostic (5.70e-2)" 0.7 0.4 0.1 0.4 0.1 0.7 0.7 0.6 0.4 0.7 0.0 0.3 0.3 0.4 1.3 0.4 0.6 1.0 55.3 0.2 0.1 1.0 3.5 0.8 0.5 0.3 0.0 0.8 1.7 0.2 27.6 0.6 0.1 0.6 0.0 5.1 0.8 0.2 1.8 2.2 0.8 0.2 0.0 1.8 0.5 0.7 0.1 0.1 0.4 2.1 0.2 0.3 0.5 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 5.0 0.0 0.8 0.4 0.0 11.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.2 1.3 2.5 0.4 0.0 0.0 0.1 0.8 0.2 0.4 0.1 0.7 1.1 0.8 0.6 0.1 0.0 0.7 0.1 0.1 0.6 0.4 0.2 0.1 0.3 0.0 0.1 0.0 0.1 0.2 4.9 0.0 0.0 0.3 4.2 1.7 1.4 0.8 1.2 5.0 1.6 2.0 6.5 1.5 0.6 1.8 4.2 0.6 10.2 0.0 1.9 0.3 27.8 0.6 1.1 3.3 0.0 0.0 0.5 0.9 7.3 2.3 1.1 0.8 8.2 1.4 2.9 7.4 3.4 3.3 0.4 0.1 2.0 1.3 13.0 161.5 0.9 9.9 0.0 2.8 5.3 1.1 8.2 0.5 0.7 0.7 0.0 0.4 3.5 1.1 0.0 2.9 0.6 10.0 0.0 0.9 1.1 5.6 8.4 0.2 1.1 11.1 3.5 6.2 0.2 0.7 CHST1 "C6ST, KSGal6ST" ENSG00000175264 "Carbohydrate sulfotransferase 1" O43916 11 45647689-45665622 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.6;thyroid gland: 20.5" "Cell type enhanced" "Detected in many" "Astrocytes: 38.5;Early spermatids: 75.9;Granulosa cells: 138.1;Spermatocytes: 96.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 9.3;TIME: 9.2;WM-115: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 10000 "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.77e-2)" "unprognostic (1.67e-1)" "unprognostic (6.37e-3)" "unprognostic (1.32e-1)" "unprognostic (2.18e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.95e-4)" "unprognostic (6.22e-2)" "unprognostic (1.64e-1)" "unprognostic (1.39e-1)" "unprognostic (1.09e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (4.64e-7)" "unprognostic (5.37e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" 2.3 3.7 31.4 0.5 34.2 0.3 1.9 0.4 35.6 2.7 0.0 1.8 0.5 2.3 0.1 1.0 5.5 0.6 5.7 32.6 13.4 8.7 2.1 4.5 0.7 6.9 12.7 5.3 1.3 3.3 11.9 0.4 6.8 2.0 0.1 1.0 6.4 0.3 8.7 1.1 1.6 0.5 2.4 7.6 1.5 4.0 24.2 0.5 20.5 1.0 0.4 2.0 2.1 16.4 0.0 0.3 0.7 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 2.0 0.0 0.0 0.2 0.3 9.3 0.1 0.0 0.1 0.8 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.5 0.7 0.2 0.0 9.2 1.8 2.6 0.0 0.0 0.0 0.0 0.0 3.8 0.0 24.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 31.4 34.2 0.4 35.6 32.6 13.4 6.9 12.7 6.8 2.4 24.2 16.4 4.4 0.0 0.0 38.5 0.0 0.1 2.9 0.4 0.0 10.0 1.4 0.4 2.1 0.0 0.3 1.8 0.0 0.0 0.2 0.0 0.0 2.6 75.9 0.7 1.1 21.1 0.0 0.0 23.9 0.2 0.1 2.3 0.5 2.5 0.0 138.1 10.4 0.3 0.2 0.0 10.2 0.0 0.0 0.9 1.7 15.0 5.6 0.9 0.0 4.7 0.0 4.5 0.0 3.0 3.9 0.3 0.0 4.9 0.0 2.4 0.0 0.1 0.2 0.5 26.3 0.7 2.6 96.8 1.4 0.2 0.0 0.0 0.5 2.3 0.0 0.9 CHST11 "C4ST, C4St-1, C4ST1, HSA269537" ENSG00000171310 "Carbohydrate sulfotransferase 11" Q9NPF2 12 104455295-104762014 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.0;choroid plexus: 59.1" "Group enriched" "Detected in many" 4 "Microglial cells: 281.1;Oligodendrocyte precursor cells: 1012.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 12.7;eosinophil: 11.2;neutrophil: 15.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 15.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052828 Approved Approved "Golgi apparatus" "Intracellular and membrane" NA NA 55000 "Cluster 5: Granulocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus" "HPA052828: AB_2681966" "unprognostic (6.35e-2)" "unprognostic (2.68e-3)" "unprognostic (2.28e-2)" "unprognostic (7.53e-2)" "unprognostic (3.45e-2)" "unprognostic (2.64e-2)" "unprognostic (1.64e-3)" "unprognostic (9.21e-3)" "unprognostic (3.12e-1)" "unprognostic (9.02e-2)" "unprognostic (1.22e-2)" "unprognostic (5.44e-2)" "prognostic unfavorable (7.59e-11)" "unprognostic (1.64e-2)" "unprognostic (5.60e-2)" "unprognostic (5.40e-3)" "prognostic unfavorable (8.42e-4)" 5.0 10.2 14.5 20.1 13.9 39.0 3.5 11.1 14.1 5.6 59.1 4.2 3.0 11.9 13.3 3.4 3.7 9.4 4.5 15.0 16.0 3.6 3.0 12.2 15.2 17.9 16.4 6.2 4.6 1.3 4.5 15.5 17.1 3.9 4.0 2.2 2.2 8.0 1.1 1.7 6.2 10.9 13.1 12.8 6.3 2.3 17.3 19.5 3.3 1.0 11.7 8.3 3.8 17.5 38.8 18.2 8.2 5.3 20.5 10.0 27.8 3.1 1.2 1.8 1.5 0.0 51.2 0.2 5.6 5.4 42.3 9.9 4.9 20.8 2.2 0.4 7.1 53.2 4.8 0.2 3.1 62.4 60.6 3.7 2.9 32.9 5.4 30.7 13.2 74.4 82.8 13.2 3.5 9.7 47.8 73.1 6.6 0.4 7.0 54.0 27.3 12.9 17.0 0.4 13.6 21.9 2.1 26.3 48.3 7.2 7.7 62.7 29.2 5.7 6.2 29.4 32.3 67.2 75.9 10.6 26.3 43.5 57.7 12.7 1.4 11.2 3.0 1.4 1.7 1.0 1.5 2.2 0.8 2.8 0.7 1.9 15.6 1.6 1.3 2.9 3.2 0.8 14.5 13.9 11.1 14.1 15.0 16.0 17.9 16.4 17.1 13.1 17.3 17.5 8.4 16.0 13.1 142.4 33.8 2.8 18.2 2.6 4.0 3.1 0.5 1.1 5.7 1.5 6.4 5.5 0.0 41.6 45.6 0.1 0.0 4.9 0.9 1.3 24.7 12.9 0.0 36.2 43.8 61.4 12.0 9.5 2.6 0.9 41.3 1.4 18.2 0.5 42.6 10.1 114.4 0.0 0.0 26.8 42.9 2.0 7.5 56.5 3.6 281.1 65.6 2.3 30.9 1012.8 3.5 28.6 0.0 17.0 64.0 3.9 0.0 6.0 8.1 0.6 6.6 1.8 12.8 0.6 2.5 0.9 2.8 26.5 49.0 15.5 0.3 3.7 CHST13 C4ST3 ENSG00000180767 "Carbohydrate sulfotransferase 13" Q8NET6 3 126524155-126543291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 59.6;testis: 18.3" "Group enriched" "Detected in some" 5 "Early spermatids: 104.0;Hepatocytes: 40.3;Spermatocytes: 126.2" "Group enriched" "Detected in many" 4 "liver cancer: 25.0;renal cancer: 6.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 5 "eosinophil: 155.2" "Lineage enriched" "Detected in many" 5 "granulocytes: 155.2" "Group enriched" "Detected in some" 8 "CACO-2: 15.6;Hep G2: 28.4;NB-4: 19.0;THP-1: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA067960 Approved "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" "HPA067960: " "unprognostic (5.68e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-2)" "unprognostic (6.42e-4)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (8.45e-3)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (5.75e-2)" "unprognostic (5.16e-2)" "unprognostic (6.68e-2)" "unprognostic (2.26e-1)" "unprognostic (1.59e-2)" 0.3 0.4 0.2 0.4 0.2 0.6 0.1 0.0 0.3 0.1 0.0 0.9 0.6 0.1 0.0 0.0 0.2 0.0 0.4 0.3 0.2 3.2 59.6 0.6 0.1 0.4 0.5 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 1.0 0.0 0.4 3.5 0.4 18.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.7 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.7 0.3 28.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.9 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.1 33.0 155.2 0.0 20.5 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 30.7 0.0 17.5 0.0 0.0 13.1 0.2 0.2 0.0 0.3 0.3 0.2 0.4 0.5 0.2 0.4 0.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 104.0 0.6 0.0 0.1 1.2 5.5 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.7 40.3 13.1 0.0 0.0 1.0 0.0 7.5 1.3 16.9 1.5 6.2 0.0 1.9 7.2 0.0 0.0 0.0 0.1 0.0 2.8 1.2 0.3 0.0 8.5 9.9 0.1 0.0 0.0 0.0 0.0 126.2 2.8 0.0 0.0 0.3 0.2 0.0 1.8 0.0 CHST4 "HEC-GLCNAC-6-ST, LSST" ENSG00000140835 "Carbohydrate sulfotransferase 4" Q8NCG5 16 71525233-71538748 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "gallbladder: 69.4" "Cell type enriched" "Detected in some" 24 "Cholangiocytes: 165.8" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 10.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 8.6;HL-60: 2.7;NB-4: 5.0;NTERA-2: 7.5;SCLC-21H: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021955 Enhanced "Intracellular and membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA021955: AB_1846723" "unprognostic (2.22e-3)" "unprognostic (1.41e-1)" "unprognostic (8.87e-2)" "unprognostic (3.35e-2)" "unprognostic (4.76e-3)" "unprognostic (6.86e-2)" "prognostic unfavorable (9.24e-4)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-6)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" 0.4 1.3 0.0 0.2 0.1 0.0 0.2 0.0 0.0 2.5 1.7 0.0 0.0 0.1 0.0 0.2 5.4 69.4 0.0 0.2 0.1 0.0 4.4 0.2 1.3 0.4 0.6 0.0 12.4 0.0 0.5 0.0 0.4 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 1.9 0.0 0.0 0.1 1.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.3 0.1 0.0 0.3 0.1 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 7.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 2.1 0.1 1.5 0.0 0.0 1.6 0.0 0.1 0.1 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.4 0.6 0.4 0.3 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.1 165.8 6.7 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 3.7 0.4 0.0 0.0 0.0 0.4 0.7 0.0 0.3 0.0 3.8 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CHST5 "FLJ22167, I-GLCNAC-6-ST" ENSG00000135702 "Carbohydrate sulfotransferase 5" Q9GZS9 16 75528535-75535247 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 85.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 5.2;Intestinal goblet cells: 3.7;Paneth cells: 8.1;Proximal enterocytes: 11.6;Undifferentiated cells: 2.6" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.4;stomach cancer: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "PC-3: 1.5" "HPA043804, HPA068029" Enhanced "Intracellular and membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "HPA043804: AB_10960563, HPA068029: " "unprognostic (6.82e-3)" "unprognostic (2.02e-1)" "unprognostic (1.99e-3)" "unprognostic (1.03e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-2)" "unprognostic (6.76e-2)" "unprognostic (1.66e-1)" "unprognostic (2.09e-2)" "unprognostic (9.03e-3)" "unprognostic (4.27e-2)" "unprognostic (2.05e-3)" "unprognostic (3.56e-1)" "unprognostic (2.52e-2)" "unprognostic (1.46e-1)" "unprognostic (1.42e-2)" 0.1 0.2 2.2 1.3 2.0 0.6 0.4 1.9 2.2 0.4 2.2 46.1 85.0 0.4 0.3 0.2 1.1 0.2 0.3 2.2 1.0 0.4 0.1 0.3 0.3 1.9 1.5 0.5 0.1 0.4 0.7 0.2 0.7 0.3 55.3 1.5 0.1 0.3 7.7 0.2 75.6 1.0 1.2 0.4 4.7 0.7 1.8 0.3 0.3 0.8 0.1 0.2 0.1 1.6 0.1 0.3 0.4 0.5 0.1 0.3 0.2 0.0 0.1 0.2 0.1 0.2 0.6 0.4 0.2 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.5 0.0 0.2 0.6 0.1 0.2 0.2 0.3 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.4 0.0 0.9 0.2 1.3 0.3 0.0 1.5 0.2 0.1 0.9 0.5 0.1 0.7 1.2 0.6 0.4 0.0 0.0 0.3 0.1 0.0 0.5 0.3 0.9 0.1 0.2 0.7 0.0 0.3 0.1 0.3 0.7 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.4 0.1 0.2 0.2 0.1 0.0 2.2 2.0 1.9 2.2 2.2 1.0 1.9 1.5 0.7 1.2 1.8 1.6 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.1 0.3 0.0 0.0 2.4 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 2.0 0.6 0.0 8.1 0.0 0.0 0.0 11.6 0.0 1.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 CHST6 MCDC1 ENSG00000183196 "Carbohydrate sulfotransferase 6" Q9GZX3 16 75472052-75495445 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.5;cervix: 9.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 60.0;Oligodendrocytes: 17.0;Respiratory ciliated cells: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 9.3;CAPAN-2: 9.9;NTERA-2: 4.8;SK-MEL-30: 4.1;U-2 OS: 5.0;WM-115: 5.4" HPA068029 Approved "Intracellular and membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "HPA068029: " "unprognostic (2.28e-2)" "unprognostic (2.25e-2)" "unprognostic (1.07e-1)" "unprognostic (3.93e-3)" "unprognostic (3.30e-2)" "unprognostic (4.02e-2)" "unprognostic (7.15e-2)" "unprognostic (1.73e-2)" "unprognostic (1.25e-1)" "unprognostic (4.48e-2)" "unprognostic (3.16e-2)" "unprognostic (1.07e-1)" "unprognostic (1.10e-7)" "unprognostic (1.23e-1)" "unprognostic (1.14e-1)" "unprognostic (5.78e-2)" "unprognostic (2.80e-4)" 0.1 5.4 8.6 0.2 11.8 0.1 0.0 8.5 7.9 9.4 3.4 0.8 4.5 0.4 0.2 1.3 1.2 0.1 1.9 7.2 10.7 0.3 0.0 0.9 0.1 12.5 13.2 0.0 0.0 0.2 1.2 0.1 11.5 0.4 1.5 0.3 2.7 0.1 0.1 0.1 3.9 0.3 10.9 0.1 0.1 0.8 13.5 0.1 0.1 0.1 0.0 0.2 0.1 11.7 0.1 0.5 0.6 9.3 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.2 9.9 0.1 1.1 0.0 0.1 0.1 0.9 0.1 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 4.8 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 4.1 1.4 0.0 0.3 0.1 0.0 5.0 0.0 0.0 0.1 0.1 2.1 0.2 0.0 5.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 8.6 11.8 8.5 7.9 7.2 10.7 12.5 13.2 11.5 10.9 13.5 11.7 0.2 0.0 2.4 7.5 0.2 0.0 1.7 0.7 0.0 0.7 0.2 0.1 1.0 0.0 4.8 3.7 0.0 2.1 0.1 3.8 0.0 0.1 1.3 60.0 0.8 0.4 0.0 0.0 0.4 0.0 0.2 1.6 0.0 7.5 1.3 0.2 0.0 0.0 0.2 0.0 1.3 4.0 0.0 0.0 0.0 1.3 0.0 0.4 0.0 1.9 0.0 0.6 0.0 6.0 17.0 0.2 8.9 0.0 0.0 1.5 8.9 0.0 16.4 0.4 0.0 1.0 0.7 0.3 0.6 0.0 0.0 0.7 0.4 0.1 2.2 3.9 CHST7 "C6ST-2, C6ST2" ENSG00000147119 "Carbohydrate sulfotransferase 7" Q9NS84 X 46573765-46598496 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 35.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 45.4;monocytes: 55.5;Peritubular cells: 60.2;Sertoli cells: 52.6;Skeletal myocytes: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.5" "Group enriched" "Detected in many" 10 "granulocytes: 10.9;monocytes: 10.2;T-cells: 18.5" "Cell line enhanced" "Detected in many" "EFO-21: 22.8;NTERA-2: 20.5;PC-3: 17.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003919, HPA030503" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 9800 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Vesicles" "HPA003919: AB_10601258, HPA030503: " "unprognostic (3.16e-1)" "prognostic favorable (7.20e-4)" "unprognostic (1.11e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" "unprognostic (7.85e-2)" "unprognostic (9.82e-3)" "unprognostic (3.52e-2)" "unprognostic (2.61e-1)" "unprognostic (2.81e-1)" "unprognostic (2.39e-3)" "unprognostic (6.71e-2)" "unprognostic (1.19e-1)" "unprognostic (8.85e-3)" "unprognostic (8.28e-2)" "unprognostic (1.50e-1)" "unprognostic (4.39e-2)" 13.2 3.4 5.4 1.7 7.3 2.5 7.5 6.4 7.0 11.2 3.7 3.7 0.8 5.8 0.4 2.5 4.9 1.9 17.4 5.4 7.1 4.0 7.5 3.6 1.8 6.1 7.3 35.3 2.0 1.2 4.2 2.0 6.0 4.1 0.8 0.9 3.5 1.4 4.4 7.3 4.0 1.4 4.7 10.2 3.4 2.1 8.0 1.4 5.8 3.9 0.7 4.5 7.7 4.0 5.5 4.7 3.9 3.5 10.8 7.5 0.2 7.6 5.4 2.0 2.6 1.2 2.1 0.0 22.8 3.1 1.3 4.1 3.8 1.3 1.7 3.2 8.1 1.1 0.3 4.1 16.6 1.9 0.1 2.5 1.1 3.8 3.1 3.4 6.2 2.5 0.0 4.7 1.5 2.6 0.7 2.4 20.5 0.4 17.0 3.6 3.2 10.3 5.5 0.2 8.8 3.4 1.1 0.2 0.9 9.6 1.3 0.4 1.4 6.1 0.6 3.3 3.5 11.0 2.4 1.7 6.8 0.1 0.4 2.4 2.2 0.7 1.5 7.1 1.4 1.2 5.8 2.8 1.2 0.6 1.2 1.1 10.9 0.6 10.2 0.8 18.5 1.9 5.4 7.3 6.4 7.0 5.4 7.1 6.1 7.3 6.0 4.7 8.0 4.0 33.8 0.0 3.1 22.9 2.5 12.4 2.0 4.8 1.2 0.8 2.2 3.7 7.4 10.0 2.6 1.8 0.0 5.3 11.5 1.7 1.9 2.8 0.0 3.6 20.8 16.3 0.0 0.0 0.9 2.5 4.3 23.6 0.0 1.6 0.0 19.7 15.7 4.5 11.5 3.3 4.1 2.9 0.0 14.2 45.4 0.3 19.0 14.1 14.2 4.7 55.5 5.2 4.1 13.0 1.0 1.8 1.5 60.2 4.7 6.7 0.7 2.1 1.9 0.8 52.6 43.1 11.2 0.5 1.3 1.3 13.2 1.4 9.9 11.4 0.9 3.3 CHST8 GALNAC-4-ST1 ENSG00000124302 "Carbohydrate sulfotransferase 8" Q9H2A9 19 33621953-33773509 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 25 "brain: 30.3;pituitary gland: 63.9" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Excitatory neurons: 11.8;Granulosa cells: 7.9;Late spermatids: 56.5;Oligodendrocyte precursor cells: 12.1" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;glioma: 4.9;testis cancer: 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 24.7;SCLC-21H: 13.5;SH-SY5Y: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016004 Enhanced "Intracellular and membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA016004: AB_1846731" "unprognostic (1.00e-1)" "unprognostic (6.58e-2)" "unprognostic (1.21e-1)" "unprognostic (1.45e-2)" "unprognostic (9.44e-2)" "unprognostic (2.96e-2)" "unprognostic (1.15e-2)" "unprognostic (5.75e-2)" "unprognostic (8.41e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.54e-1)" "unprognostic (6.98e-8)" "unprognostic (9.37e-3)" "unprognostic (2.61e-1)" "unprognostic (3.28e-1)" "unprognostic (3.87e-2)" 0.7 0.7 7.8 0.3 6.7 0.0 1.8 11.5 10.4 0.9 0.1 0.4 0.0 0.6 0.0 0.3 1.2 0.9 0.4 11.0 11.4 0.1 0.1 0.2 0.4 29.8 7.2 1.0 0.7 0.0 63.9 0.0 30.3 0.7 0.0 0.7 0.2 0.0 0.1 0.3 0.3 0.1 5.4 1.3 0.3 1.4 11.5 0.0 0.6 0.0 0.2 0.3 0.5 8.2 0.0 0.0 0.0 0.3 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 4.7 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 3.6 0.0 0.0 0.0 0.1 24.7 0.0 0.4 13.5 23.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.8 6.7 11.5 10.4 11.0 11.4 29.8 7.2 30.3 5.4 11.5 8.2 0.2 0.0 0.0 0.7 0.0 0.8 0.4 0.0 0.0 3.1 3.8 0.6 5.1 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.3 0.2 0.4 0.0 0.0 11.8 0.0 1.3 0.2 0.0 0.1 0.0 7.9 0.4 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 56.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 12.1 3.6 0.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 4.7 0.0 0.3 3.2 0.5 0.7 0.3 0.1 0.0 0.0 0.0 0.0 1.1 CHST9 "GALNAC-4-ST2, GALNAC4ST-2" ENSG00000154080 "Carbohydrate sulfotransferase 9" Q7L1S5 18 26906481-27185308 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 13.8" "Cell type enhanced" "Detected in many" "Club cells: 115.2;Muller glia cells: 69.2;Oligodendrocyte precursor cells: 167.4;Respiratory ciliated cells: 311.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 9.3;Hep G2: 13.8;RPTEC TERT1: 41.8;SCLC-21H: 9.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA011393 Uncertain "Intracellular and membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA011393: AB_1846733" "unprognostic (9.24e-3)" "unprognostic (1.13e-2)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (4.53e-3)" "unprognostic (9.98e-3)" "unprognostic (9.21e-3)" "unprognostic (7.92e-2)" "unprognostic (1.61e-1)" "unprognostic (2.04e-2)" "unprognostic (3.54e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-2)" "unprognostic (1.38e-1)" "unprognostic (3.93e-3)" 0.0 0.2 0.8 0.1 0.9 0.0 2.9 0.7 2.4 2.8 0.0 1.6 0.2 0.1 0.4 1.6 10.3 3.1 2.6 2.7 1.2 1.6 8.2 4.3 0.0 3.5 2.3 0.0 9.3 0.0 1.9 0.0 1.2 3.5 0.2 7.3 13.8 1.8 0.2 0.1 0.3 0.1 2.0 5.7 0.7 6.9 1.2 1.0 0.0 0.9 0.6 1.5 0.7 1.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 41.8 0.0 9.0 0.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.7 2.4 2.7 1.2 3.5 2.3 1.2 2.0 1.2 1.9 0.1 0.0 2.7 24.8 0.0 0.6 32.6 56.6 4.6 1.3 8.2 8.0 9.2 35.8 115.2 5.5 0.0 0.4 0.1 0.0 11.7 13.0 7.1 49.9 0.7 0.3 3.5 0.0 10.1 0.6 0.1 4.2 0.0 1.8 5.1 0.1 0.0 10.7 0.3 0.0 29.3 0.1 22.4 0.0 0.0 4.4 0.6 0.5 7.2 1.0 0.0 69.2 0.0 167.4 1.0 1.3 0.0 0.4 0.0 8.9 0.0 0.3 311.6 3.2 0.0 3.2 3.7 0.9 1.3 4.7 0.0 0.3 0.4 0.0 0.0 40.3 CHSY3 "CHSY-2, CSS3" ENSG00000198108 "Chondroitin sulfate synthase 3" Q70JA7 5 129904465-130186634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 509.1;Inhibitory neurons: 349.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 2.0;basal ganglia: 2.6;cerebral cortex: 2.9;hippocampal formation: 2.5;white matter: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.1;ASC TERT1: 11.5;HSkMC: 7.6;TIME: 7.4;U-138 MG: 14.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044612 Uncertain "Intracellular and membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA044612: AB_10795883" "unprognostic (3.43e-2)" "unprognostic (6.28e-3)" "unprognostic (1.76e-2)" "unprognostic (5.83e-2)" "unprognostic (5.88e-2)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (9.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.08e-6)" "unprognostic (5.22e-3)" "unprognostic (9.93e-2)" "unprognostic (4.61e-3)" "unprognostic (1.74e-2)" 6.0 0.5 2.0 1.0 2.6 0.0 2.8 0.0 2.9 4.5 0.0 0.7 0.5 1.5 0.1 0.6 1.1 2.8 1.3 2.5 0.2 0.2 1.7 1.8 0.5 0.0 0.4 0.3 0.3 0.4 0.3 2.2 0.0 0.5 0.5 1.0 0.5 0.6 1.0 1.3 0.5 2.0 0.2 0.7 0.5 0.7 0.4 0.2 1.2 0.5 0.4 1.7 1.9 1.1 0.0 0.1 1.2 0.0 13.1 11.5 1.0 3.0 0.1 0.4 0.4 0.0 0.1 0.0 0.3 4.6 0.0 0.0 0.0 0.1 0.0 0.0 1.6 1.9 5.6 0.5 1.2 0.0 0.0 7.6 0.0 0.1 1.2 0.6 3.2 0.0 0.0 1.9 5.2 0.0 0.0 0.0 0.7 0.0 1.2 0.4 5.7 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.3 1.1 0.2 0.5 7.4 14.2 3.0 0.2 2.0 0.0 0.0 0.0 0.3 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.6 0.0 2.9 2.5 0.2 0.0 0.4 0.0 0.2 0.4 1.1 2.0 9.6 1.1 20.2 0.0 0.5 0.0 0.0 1.2 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.9 0.5 14.8 2.4 0.0 0.0 509.1 0.0 0.1 2.9 0.0 0.3 0.0 4.1 3.6 1.8 1.9 0.0 349.5 0.0 0.0 1.3 0.7 0.1 1.2 0.1 3.6 87.1 0.0 1.3 0.0 76.9 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.1 6.6 0.9 6.3 1.6 0.7 0.3 0.3 0.4 0.2 0.6 0.0 0.1 CIAO2A "CIA2A, FAM96A, FLJ22875" ENSG00000166797 "Cytosolic iron-sulfur assembly component 2A" Q9H5X1 15 64072565-64093857 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 262.4" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 74.8;Cytotrophoblasts: 116.5;Extravillous trophoblasts: 100.6;Hofbauer cells: 218.2;Syncytiotrophoblasts: 88.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040459, HPA063729" Approved Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "HPA040459: AB_10796456, HPA063729: AB_2685105" "unprognostic (1.15e-1)" "unprognostic (8.49e-2)" "unprognostic (6.59e-2)" "unprognostic (3.58e-1)" "unprognostic (1.30e-1)" "unprognostic (8.07e-2)" "unprognostic (4.06e-3)" "unprognostic (5.02e-2)" "unprognostic (7.16e-2)" "unprognostic (5.87e-2)" "unprognostic (1.04e-1)" "unprognostic (6.48e-3)" "unprognostic (8.06e-3)" "unprognostic (1.81e-1)" "unprognostic (2.58e-1)" "unprognostic (2.11e-2)" "unprognostic (1.50e-2)" 27.8 68.6 23.1 53.6 26.0 70.7 48.5 25.7 26.7 31.5 39.1 82.8 107.9 22.6 41.1 30.1 32.1 43.0 78.0 22.0 24.6 81.3 262.4 43.4 105.3 26.1 24.0 20.6 59.8 75.5 24.6 65.5 26.6 39.1 68.4 24.7 44.0 26.8 125.5 19.4 86.8 23.8 26.4 52.8 68.8 20.7 26.9 60.3 80.2 97.4 66.9 46.3 20.3 32.0 114.6 168.6 104.3 71.7 91.7 110.7 61.2 92.7 105.4 120.2 133.5 157.7 172.9 186.9 157.4 56.2 155.7 118.3 197.9 90.2 95.4 171.3 124.2 156.2 137.7 161.2 70.7 240.5 123.1 90.8 87.2 76.7 67.6 84.5 130.1 118.5 222.3 148.8 89.5 197.8 100.1 202.8 144.6 148.9 96.3 154.5 139.8 410.4 154.3 127.0 112.2 87.5 76.8 150.9 180.6 113.9 120.6 243.6 83.0 98.2 129.4 104.7 193.6 144.4 353.8 186.4 109.5 429.3 96.9 122.4 255.8 117.0 67.3 254.1 83.0 346.0 94.8 88.1 231.6 345.5 75.5 74.4 132.0 86.9 228.3 386.5 146.1 269.0 23.1 26.0 25.7 26.7 22.0 24.6 26.1 24.0 26.6 26.4 26.9 32.0 10.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 0.0 0.0 0.0 0.0 116.5 10.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 100.6 13.2 0.0 0.0 0.0 0.0 0.0 0.0 218.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 88.8 2.0 0.0 0.0 0.0 CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 138.1;Leydig cells: 231.5;Peritubular cells: 57.6;Theca cells: 83.5" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.2;ASC TERT1: 2.5;EFO-21: 1.1;HSkMC: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" 49.8 0.8 0.2 9.5 0.2 0.1 21.9 0.3 0.3 44.9 0.1 20.3 2.3 13.8 3.6 11.0 15.8 36.8 27.4 0.2 0.2 1.0 1.6 2.9 1.6 0.2 0.2 7.5 3.0 0.3 0.7 2.5 0.2 3.1 6.9 0.5 9.4 4.8 15.5 14.0 22.6 51.0 0.2 0.6 8.3 12.1 0.2 1.8 2.4 32.9 0.8 26.9 28.1 0.2 0.0 0.0 0.0 0.0 4.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 8.1 0.0 0.0 0.0 0.0 5.2 0.1 0.2 0.0 0.9 0.4 0.5 2.1 0.0 0.4 1.8 0.0 0.0 0.2 0.1 0.0 0.1 1.7 1.2 42.9 1.5 0.0 0.0 0.3 0.0 0.0 138.1 4.1 1.7 0.0 0.1 2.2 0.1 0.1 0.0 0.6 0.1 2.0 0.0 11.9 7.1 231.5 1.7 1.8 1.9 0.0 0.2 0.0 1.0 0.3 0.0 0.0 57.6 0.3 0.1 0.0 0.0 0.0 0.1 0.0 14.7 6.6 0.6 0.3 0.1 6.1 0.0 1.6 83.5 0.2 0.0 CILP2 MGC45771 ENSG00000160161 "Cartilage intermediate layer protein 2" Q8IUL8 19 19538248-19546659 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.5" "Cell type enhanced" "Detected in some" "Early spermatids: 26.2;Late spermatids: 21.8;Sertoli cells: 6.6;Spermatocytes: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.6;HEK 293: 2.8;NB-4: 2.2;THP-1: 2.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "medulla oblongata: 2.7;spinal cord: 7.3" HPA041847 Uncertain "Secreted to extracellular matrix" NA NA 22000000 "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA041847: AB_10795599" "unprognostic (6.51e-2)" "unprognostic (2.54e-2)" "unprognostic (5.42e-4)" "prognostic unfavorable (3.22e-6)" "unprognostic (4.81e-2)" "unprognostic (1.73e-1)" "unprognostic (4.31e-2)" "unprognostic (4.13e-3)" "unprognostic (4.48e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (5.09e-2)" "unprognostic (1.41e-2)" "unprognostic (0.00e+0)" "unprognostic (1.59e-2)" "unprognostic (3.19e-2)" "unprognostic (3.12e-3)" "unprognostic (1.36e-2)" 0.8 0.0 0.4 0.2 0.7 1.0 0.3 0.0 0.4 0.3 0.0 0.1 0.0 0.2 0.1 0.0 0.4 1.5 0.4 0.4 1.2 0.3 0.2 0.4 0.3 0.2 0.2 1.6 0.0 0.1 0.3 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.3 0.3 0.1 0.1 0.0 0.2 0.0 5.5 0.9 0.0 1.0 0.0 0.1 0.3 0.2 0.1 0.0 0.1 0.1 0.1 4.6 0.1 0.6 0.6 0.0 0.3 0.0 1.3 0.5 0.0 1.2 0.2 0.0 0.5 0.1 0.0 0.0 0.3 2.8 0.0 0.1 0.1 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 2.2 1.7 1.5 0.9 0.3 0.0 0.0 0.0 0.0 0.1 1.2 0.3 1.5 0.1 0.2 0.3 2.8 0.0 0.0 0.5 0.2 0.1 0.4 1.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.4 0.4 1.2 0.2 0.2 0.2 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.0 0.5 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 26.2 0.3 0.3 0.1 0.0 0.0 0.2 0.0 0.2 1.5 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.3 21.8 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 1.4 0.0 0.1 0.0 0.0 6.6 0.4 0.3 27.8 4.0 0.7 0.6 0.0 0.2 0.1 0.0 0.5 CKLF "C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1" ENSG00000217555 "Chemokine like factor" Q9UBR5 16 66552563-66566251 "Predicted membrane proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 345.1;Spermatocytes: 300.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1384.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA062779 Approved Vesicles "Secreted to blood" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062779: AB_2684867" "unprognostic (1.64e-2)" "unprognostic (2.17e-2)" "unprognostic (1.88e-1)" "unprognostic (4.97e-2)" "unprognostic (3.06e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (2.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.79e-2)" "unprognostic (8.05e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.06e-9)" "unprognostic (2.36e-1)" "unprognostic (2.65e-1)" "prognostic favorable (2.22e-4)" "unprognostic (1.07e-1)" 36.5 31.1 26.3 54.8 26.2 68.2 36.0 27.4 29.8 27.7 25.9 42.1 31.8 23.8 27.4 19.2 31.1 40.3 16.5 25.7 28.8 21.0 29.6 36.2 61.5 28.1 27.6 25.6 17.9 58.0 19.7 29.7 28.9 15.5 42.5 9.7 19.7 18.4 14.8 16.9 38.7 33.5 27.9 67.0 25.6 56.8 26.4 90.0 23.7 20.1 51.2 46.1 20.0 29.6 194.6 169.2 34.7 101.5 92.7 76.1 25.5 95.2 72.4 101.7 150.9 158.8 231.4 75.8 116.6 81.8 106.4 102.5 70.5 57.2 142.1 94.2 35.3 55.5 145.0 197.3 56.0 175.7 144.1 52.0 45.3 126.9 44.9 122.1 122.8 229.4 90.8 212.8 129.2 64.8 169.9 172.1 11.5 114.0 273.1 287.5 184.2 215.6 343.2 106.3 48.8 58.8 290.5 19.3 93.0 23.3 55.5 116.5 76.6 146.5 131.8 51.0 113.5 100.3 224.0 393.0 123.5 151.5 121.1 807.1 380.9 773.3 187.6 203.9 238.9 100.6 174.8 186.6 317.6 97.7 92.7 126.4 1384.5 187.6 199.2 161.6 236.0 401.2 26.3 26.2 27.4 29.8 25.7 28.8 28.1 27.6 28.9 27.9 26.4 29.6 65.7 19.2 49.0 0.0 68.7 27.3 24.7 84.2 12.0 8.4 80.8 94.0 1.8 87.2 50.8 57.0 0.0 54.8 109.7 57.1 17.6 141.4 67.7 34.8 21.5 52.4 33.0 63.5 0.0 130.0 117.7 38.6 21.4 17.5 345.1 17.7 67.5 38.4 247.4 1.7 0.0 73.6 61.1 138.2 238.4 31.4 49.4 244.2 40.9 0.0 157.8 28.1 188.4 0.0 0.0 224.2 51.3 30.1 94.6 10.0 95.9 83.4 79.3 9.0 32.9 24.5 38.1 300.0 77.1 30.8 23.0 17.4 192.6 23.9 79.0 25.8 CKMT1A CKMT1 ENSG00000223572 "Creatine kinase, mitochondrial 1A" P12532 15 43692886-43699222 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 83.9;intestine: 75.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 73.0;Distal enterocytes: 110.5;Intestinal goblet cells: 53.4;Paneth cells: 57.4;Proximal enterocytes: 94.5;Syncytiotrophoblasts: 94.0;Undifferentiated cells: 92.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 127.5;hTCEpi: 56.8;OE19: 144.3;SK-BR-3: 107.8;T-47d: 100.3" HPA043491 Uncertain "Intracellular and membrane" NA NA 2000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA043491: AB_2678510" "unprognostic (2.04e-2)" "unprognostic (2.53e-2)" "unprognostic (1.17e-1)" "unprognostic (4.02e-3)" "unprognostic (3.80e-1)" "unprognostic (7.44e-2)" "unprognostic (2.21e-1)" "unprognostic (3.10e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.51e-2)" "unprognostic (3.78e-9)" "unprognostic (3.52e-2)" "unprognostic (1.03e-1)" "unprognostic (7.37e-2)" "unprognostic (1.73e-3)" 1.8 3.8 20.8 7.1 22.1 0.0 7.7 29.3 46.4 10.1 12.6 75.0 70.6 0.5 0.4 83.9 2.1 9.4 0.8 21.9 27.3 6.0 0.2 0.9 0.1 24.9 15.8 0.1 3.5 12.3 8.5 9.5 26.9 4.4 69.4 31.8 31.4 1.1 0.1 38.0 63.1 3.4 10.7 0.1 23.3 0.3 23.0 0.2 2.8 0.0 14.7 8.3 26.1 25.7 0.3 2.9 0.7 0.1 1.3 0.0 31.9 0.0 0.0 0.0 0.0 6.8 22.1 0.1 1.4 0.0 2.4 127.5 22.4 39.0 0.0 0.0 17.1 0.0 2.1 0.7 0.0 0.0 6.1 0.2 56.8 0.0 10.3 0.0 0.0 5.0 5.7 0.1 0.0 34.8 0.0 0.2 10.1 144.3 8.2 0.1 0.0 6.7 6.7 4.7 47.1 20.0 0.0 107.8 8.6 2.9 100.3 0.8 0.0 0.0 2.3 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 22.1 29.3 46.4 21.9 27.3 24.9 15.8 26.9 10.7 23.0 25.7 0.1 0.0 0.0 2.3 0.3 17.7 10.5 30.3 1.8 6.7 4.2 5.2 0.5 10.0 14.9 1.8 20.9 73.0 0.1 110.5 27.4 4.2 0.0 0.7 0.0 0.3 18.0 0.0 10.6 20.2 23.5 0.4 26.0 0.8 8.9 1.5 0.0 0.0 4.5 6.7 9.0 53.4 12.2 0.0 0.7 0.2 0.0 0.0 5.4 1.0 0.0 4.8 0.0 1.5 1.6 12.9 57.4 0.0 0.0 2.7 94.5 1.0 4.1 11.6 0.0 0.0 0.9 0.0 0.1 16.1 18.5 94.0 0.4 0.0 92.7 20.1 CKMT1B "CKMT, CKMT1, UMTCK" ENSG00000237289 "Creatine kinase, mitochondrial 1B" P12532 15 43593054-43604901 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.5;esophagus: 74.3;intestine: 80.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 122.4;Distal enterocytes: 146.4;Intestinal goblet cells: 78.3;Paneth cells: 69.9;Proximal enterocytes: 124.6;Syncytiotrophoblasts: 137.9;Undifferentiated cells: 123.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 139.8;hTCEpi: 69.2;OE19: 156.0;SK-BR-3: 183.1;T-47d: 100.7" HPA043491 Uncertain "Intracellular and membrane" NA NA 2000000 "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA043491: AB_2678510" "unprognostic (3.47e-2)" "unprognostic (9.73e-3)" "unprognostic (3.10e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (1.29e-1)" "unprognostic (1.96e-1)" "unprognostic (5.19e-2)" "unprognostic (2.84e-1)" "unprognostic (3.64e-1)" "unprognostic (5.75e-2)" "unprognostic (2.39e-1)" "unprognostic (1.15e-2)" "unprognostic (2.26e-8)" "unprognostic (1.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.43e-2)" "unprognostic (4.36e-2)" 1.9 1.9 24.6 6.3 25.1 0.0 6.0 38.0 58.5 8.0 14.3 80.7 63.4 0.3 0.4 74.3 1.9 8.9 0.7 26.5 31.5 5.3 0.1 0.7 0.1 32.4 25.2 0.1 3.1 11.9 9.5 12.8 34.6 3.1 66.0 23.4 28.5 0.8 0.1 26.7 49.4 4.0 13.8 0.0 29.6 0.2 28.6 0.1 6.2 0.0 13.3 8.4 22.0 22.2 0.3 0.9 0.8 0.0 0.2 0.0 35.3 0.0 0.0 0.1 0.1 7.8 23.8 0.0 1.0 0.0 7.2 139.8 28.4 55.8 0.1 0.8 16.0 0.0 3.0 3.8 0.0 0.1 8.6 0.0 69.2 0.0 6.9 0.0 0.0 5.9 9.1 0.0 0.0 38.2 0.1 0.2 12.0 156.0 14.9 0.0 0.0 0.8 3.0 3.7 55.4 19.5 0.9 183.1 10.9 2.3 100.7 0.0 0.0 0.1 1.8 0.2 2.3 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 25.1 38.0 58.5 26.5 31.5 32.4 25.2 34.6 13.8 28.6 22.2 0.1 0.0 0.5 2.6 0.1 25.1 10.4 40.5 3.4 7.5 3.8 4.1 0.4 5.7 12.7 5.5 18.8 122.4 0.4 146.4 21.5 4.0 0.0 0.9 0.0 0.5 21.0 0.0 37.6 28.0 26.1 0.5 33.1 0.5 0.0 1.1 0.0 0.0 9.4 6.7 36.5 78.3 10.2 0.0 0.7 0.0 0.0 0.1 3.6 2.8 0.0 2.2 0.0 5.0 2.4 18.6 69.9 0.0 0.1 2.0 124.6 0.9 6.0 12.2 0.0 0.0 0.7 0.0 0.0 17.5 24.7 137.9 0.6 0.0 123.7 19.9 CKMT2 SMTCK ENSG00000131730 "Creatine kinase, mitochondrial 2" P17540 5 81233320-81266398 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 49 "heart muscle: 1240.1;skeletal muscle: 1430.8;tongue: 2324.4" "Cell type enriched" "Detected in many" 20 "Cardiomyocytes: 814.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 7 "NK-cells: 1.1" "Cell line enhanced" "Detected in many" "BEWO: 3.5;T-47d: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051880 Enhanced NA NA 3000000 "Cluster 48: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA051880: AB_2681650" "unprognostic (3.64e-3)" "unprognostic (1.15e-1)" "unprognostic (2.82e-3)" "unprognostic (1.88e-2)" "unprognostic (1.21e-2)" "unprognostic (2.41e-2)" "unprognostic (1.73e-2)" "unprognostic (3.57e-2)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (5.34e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.75e-3)" 18.2 33.6 12.3 0.8 15.0 0.1 4.6 17.3 12.3 8.1 24.4 3.2 1.1 6.4 11.4 20.2 6.9 8.1 1240.1 11.2 15.0 14.7 1.0 2.5 1.3 16.3 16.8 10.2 7.7 15.7 4.5 0.7 14.9 13.1 0.7 1.6 26.3 13.1 1430.8 4.7 2.8 8.8 12.0 1.8 17.9 3.6 16.1 0.8 4.9 2324.4 0.4 4.1 4.1 17.7 0.3 0.7 0.8 1.3 1.9 0.4 3.5 0.1 0.0 0.0 0.0 2.4 0.2 1.4 0.4 0.0 1.0 0.0 0.0 0.0 0.0 1.5 2.4 0.1 1.0 3.2 2.6 0.6 0.2 0.8 0.0 0.0 0.0 0.3 0.0 2.1 0.3 0.5 0.0 2.2 1.2 0.2 1.0 0.0 0.7 0.6 1.0 0.1 0.0 0.0 1.4 1.0 1.2 0.3 1.4 1.5 6.3 0.3 0.7 0.4 1.2 0.7 0.2 0.2 0.1 1.3 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 12.3 15.0 17.3 12.3 11.2 15.0 16.3 16.8 14.9 12.0 16.1 17.7 1.8 0.0 0.5 40.1 0.0 0.1 0.4 0.0 1.2 0.9 0.9 0.8 814.1 7.2 0.6 12.9 0.0 0.1 0.0 0.1 37.2 1.7 25.1 13.6 3.5 9.8 0.0 0.0 11.4 0.6 0.4 16.2 6.6 27.8 0.0 0.8 0.0 0.0 0.1 0.0 18.1 0.3 0.0 0.0 0.0 2.2 7.2 0.3 3.6 23.4 0.0 1.4 0.0 4.5 9.1 0.4 0.0 15.1 0.0 0.3 0.3 0.6 0.7 1.0 0.0 11.6 15.0 1.0 0.4 0.1 0.1 0.3 0.8 23.7 2.5 0.2 CLCA1 "CaCC, CLCRG1" ENSG00000016490 "Chloride channel accessory 1" A8K7I4 1 86468368-86500259 "Predicted secreted proteins, Transporters" "Calcium transport, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 1399.9" "Cell type enriched" "Detected in some" 16 "Intestinal goblet cells: 3524.6" "Group enriched" "Detected in some" 9 "colorectal cancer: 86.8;pancreatic cancer: 27.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.1;NB-4: 2.5;RPMI-8226: 2.9;SH-SY5Y: 1.8;U-2197: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052787, HPA059301" Enhanced "Secreted to digestive system" NA NA 77000 "Cluster 9: Intestine - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA052787: AB_2681947, HPA059301: AB_2683971" "prognostic favorable (2.98e-4)" "unprognostic (3.42e-1)" "unprognostic (8.61e-2)" "unprognostic (1.06e-1)" 1.1 0.0 0.0 109.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 739.9 909.7 1.2 0.0 0.3 0.1 0.7 0.0 0.0 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 1061.8 0.0 0.0 0.5 0.0 0.0 1399.9 15.4 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 24.1 0.0 0.0 0.1 0.0 0.0 0.0 6.7 0.0 0.3 0.0 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 3524.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 54.8 0.0 0.0 0.0 213.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 68.3 0.1 CLCC1 MCLC ENSG00000121940 "Chloride channel CLIC like 1" Q96S66 1 108927361-108963504 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009087, HPA013210" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA009087: AB_1078532, HPA013210: AB_1846895" "unprognostic (2.95e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.33e-5)" "unprognostic (4.32e-2)" "unprognostic (2.55e-1)" "unprognostic (1.48e-1)" "unprognostic (2.40e-2)" "unprognostic (1.45e-1)" "unprognostic (5.30e-2)" "unprognostic (9.23e-2)" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (7.50e-2)" "unprognostic (1.74e-1)" "unprognostic (2.04e-1)" "unprognostic (4.68e-3)" "unprognostic (9.65e-2)" 14.6 16.5 10.1 11.4 14.3 6.1 16.3 10.6 11.7 17.0 7.8 15.4 13.2 17.0 24.3 9.9 15.1 14.0 18.3 10.7 11.5 11.0 22.2 13.0 10.5 12.8 10.9 18.6 24.8 21.3 18.3 17.7 12.1 20.2 13.2 11.8 22.3 20.0 27.2 10.3 12.7 14.9 11.0 11.5 16.1 7.6 11.8 5.2 21.9 24.8 10.8 15.2 13.4 16.0 44.2 22.3 25.1 45.8 36.7 33.9 35.6 43.8 34.2 30.1 34.2 22.6 21.0 10.8 43.7 33.3 18.5 17.1 23.9 16.1 39.4 38.0 23.2 30.4 24.7 23.5 28.9 28.7 28.2 25.2 21.9 33.2 25.7 28.3 27.1 12.1 38.6 47.7 22.1 18.9 2.3 10.1 21.5 16.6 19.8 24.5 13.1 31.2 24.3 30.5 15.9 22.7 46.9 49.6 38.9 18.9 15.9 19.7 26.7 38.3 27.7 35.1 38.4 32.1 33.3 17.1 44.7 21.8 82.5 4.1 5.6 6.1 5.6 8.4 6.1 6.1 4.5 4.4 5.6 3.2 4.9 4.5 1.4 4.7 12.4 6.4 6.8 4.4 10.1 14.3 10.6 11.7 10.7 11.5 12.8 10.9 12.1 11.0 11.8 16.0 13.3 25.6 20.9 26.8 11.8 3.7 14.0 11.7 1.8 12.3 11.8 9.1 5.9 20.0 18.0 11.0 29.2 28.7 9.0 7.1 0.0 18.6 6.7 8.1 21.3 10.9 3.6 5.9 25.0 21.1 12.8 19.5 10.7 13.5 12.0 16.3 9.7 22.3 13.1 21.9 30.3 9.0 16.2 6.7 5.1 2.8 19.9 9.3 8.8 14.0 12.0 11.4 3.1 35.7 39.3 17.7 3.8 18.8 17.7 17.7 7.2 5.0 14.9 18.9 19.7 18.6 10.7 5.5 5.4 6.4 6.3 18.5 8.4 12.5 9.8 9.9 CLCF1 "BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6" ENSG00000175505 "Cardiotrophin like cytokine factor 1" Q9UBD9 11 67364168-67374177 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 41.8;Glandular and luminal cells: 104.9;Pancreatic endocrine cells: 56.2;Prostatic glandular cells: 56.4;Urothelial cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SiHa: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA042444 Uncertain Approved "Nuclear bodies,Vesicles" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" "Nuclear bodies, Vesicles" "HPA042444: AB_10794527" "unprognostic (2.68e-1)" "unprognostic (7.87e-3)" "unprognostic (6.21e-3)" "unprognostic (2.62e-2)" "prognostic unfavorable (9.91e-4)" "unprognostic (1.61e-2)" "unprognostic (1.09e-3)" "unprognostic (1.47e-2)" "unprognostic (5.08e-2)" "unprognostic (2.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.54e-1)" "unprognostic (1.67e-2)" "unprognostic (1.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.17e-2)" "unprognostic (2.37e-1)" 16.2 6.0 1.3 8.0 0.5 13.7 5.3 0.0 1.5 13.9 0.9 13.4 1.4 16.6 1.0 4.4 17.1 17.7 8.8 1.0 0.6 19.0 4.2 9.3 5.3 1.4 0.5 6.7 6.5 0.2 6.5 4.2 0.4 7.2 1.7 1.4 9.1 1.8 1.5 2.6 9.4 8.3 0.0 8.1 11.2 1.9 2.1 0.7 9.7 1.9 4.4 18.1 7.6 0.2 15.1 31.4 2.2 9.7 4.2 5.8 0.0 20.9 11.6 14.4 7.0 5.1 40.3 9.1 17.1 26.8 17.5 10.3 0.4 10.7 6.3 0.5 0.3 0.1 23.9 4.0 13.6 1.9 2.4 7.6 2.6 15.0 6.5 27.4 3.1 0.0 3.5 0.4 15.0 12.0 0.1 6.8 8.1 18.9 28.8 0.9 4.8 0.5 22.7 0.8 0.1 1.6 57.8 2.2 1.3 4.4 1.3 2.5 12.5 27.6 11.6 35.4 31.5 2.0 0.1 1.0 35.4 1.8 11.1 0.0 0.9 15.2 10.5 3.4 6.2 10.8 4.8 8.3 1.3 13.8 0.1 3.5 0.3 0.2 10.5 0.0 1.1 3.2 1.3 0.5 0.0 1.5 1.0 0.6 1.4 0.5 0.4 0.0 2.1 0.2 4.2 16.0 4.8 1.3 10.6 3.7 25.9 6.5 1.8 0.0 14.5 2.4 0.8 25.8 9.6 7.3 0.0 0.4 10.0 3.8 1.9 24.0 1.8 41.8 19.4 6.2 1.2 0.0 0.7 11.8 0.6 14.0 5.1 104.9 3.8 2.1 2.9 1.0 1.2 0.0 0.5 2.3 6.1 0.3 10.7 4.7 3.4 6.7 8.8 1.0 6.5 1.7 3.1 0.5 0.1 56.2 14.3 0.0 9.5 56.4 0.2 5.2 1.7 0.3 0.0 32.6 10.4 0.3 0.9 1.6 4.4 0.1 9.7 0.1 1.5 65.2 CLDN10 "CPETRL3, OSP-L" ENSG00000134873 "Claudin 10" P78369 13 95433604-95579759 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 135.2;pancreas: 216.5;salivary gland: 91.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 182.4;Cholangiocytes: 328.8;Club cells: 251.6;Ductal cells: 394.1;Glandular and luminal cells: 220.2;Proximal tubular cells: 285.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 19.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 1.3;neutrophil: 4.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 4.1" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 14.9;NTERA-2: 12.7;RPTEC TERT1: 29.0;SuSa: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012969, HPA042348" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB012969: AB_2533386, HPA042348: AB_2677955" "unprognostic (6.45e-2)" "unprognostic (5.72e-2)" "unprognostic (3.35e-1)" "unprognostic (4.60e-2)" "unprognostic (4.73e-2)" "unprognostic (2.46e-3)" "unprognostic (6.91e-2)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "unprognostic (1.91e-3)" "unprognostic (2.59e-3)" "unprognostic (7.93e-2)" "prognostic favorable (7.46e-5)" "unprognostic (1.11e-2)" "unprognostic (9.94e-2)" "prognostic favorable (2.13e-4)" "unprognostic (4.75e-3)" 1.0 0.1 33.0 0.0 31.3 3.2 3.1 28.6 45.8 30.4 24.1 0.3 1.1 9.3 20.8 7.9 19.2 25.5 0.5 32.6 30.5 135.2 3.7 2.1 0.0 27.9 30.2 0.9 216.5 0.4 3.1 0.8 27.2 1.3 0.4 2.7 91.5 0.4 0.1 16.8 0.2 0.4 27.4 0.7 0.9 1.5 30.1 0.5 0.2 0.7 27.4 0.5 0.4 29.8 0.0 0.0 0.9 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 2.7 0.0 4.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.3 1.9 0.0 0.0 2.9 0.0 0.1 0.0 0.5 14.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 12.7 0.2 0.0 0.0 0.1 0.0 29.0 0.0 0.2 0.1 0.0 0.0 0.0 73.3 0.7 1.8 0.6 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 33.0 31.3 28.6 45.8 32.6 30.5 27.9 30.2 27.2 27.4 30.1 29.8 0.6 0.0 0.0 93.4 1.0 0.3 5.5 182.4 0.0 0.3 22.6 5.0 0.8 328.8 251.6 99.3 0.0 15.0 0.4 0.0 135.0 394.1 3.4 83.2 28.5 4.2 0.0 0.0 0.6 82.5 7.9 1.4 0.0 220.2 0.0 0.1 1.1 0.4 1.9 0.0 1.6 0.0 77.3 0.3 0.3 2.5 0.0 2.8 69.4 4.7 1.6 78.7 0.0 33.7 0.4 103.1 0.0 0.4 0.1 22.1 0.0 285.9 43.3 3.8 6.6 0.2 16.8 12.2 19.9 1.5 0.6 23.1 2.2 0.5 0.0 5.0 CLDN15 ENSG00000106404 "Claudin 15" P56746 7 101232092-101238820 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "adipose tissue: 65.4;intestine: 259.8" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 594.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (8.85e-2)" "unprognostic (1.48e-1)" "unprognostic (4.93e-2)" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (6.81e-2)" "unprognostic (1.58e-2)" "unprognostic (1.03e-1)" "unprognostic (6.56e-2)" "unprognostic (1.79e-1)" "prognostic favorable (2.56e-4)" "unprognostic (2.02e-2)" "prognostic unfavorable (5.31e-5)" "unprognostic (9.98e-2)" "unprognostic (2.89e-2)" "unprognostic (9.64e-2)" "prognostic favorable (3.30e-4)" 65.4 3.9 8.8 7.3 10.4 13.6 20.2 9.4 11.0 14.9 6.3 22.3 259.8 11.1 2.2 7.2 16.3 7.3 8.6 8.6 9.1 23.9 22.2 10.7 9.8 11.4 9.8 18.5 7.8 2.0 6.8 5.9 11.3 11.4 7.9 8.8 6.5 2.6 3.6 11.2 183.9 4.4 8.4 22.6 10.0 8.3 10.1 8.7 9.3 1.3 7.0 9.8 11.6 18.2 3.3 10.1 5.3 8.4 8.1 6.5 3.6 3.2 4.0 3.9 5.6 7.3 3.8 11.0 5.6 2.1 6.4 6.1 8.8 1.8 3.8 13.8 18.5 5.1 6.9 9.0 7.1 5.7 10.6 6.2 8.8 5.1 6.7 8.3 3.3 10.9 24.3 17.4 3.0 11.7 9.1 32.6 4.1 4.9 6.9 12.3 4.5 9.3 2.3 4.1 5.1 18.1 2.9 5.5 16.4 7.2 5.1 11.4 4.7 12.8 11.0 19.5 3.9 18.3 24.9 11.7 3.6 14.9 7.5 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.3 0.0 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.3 0.1 0.2 8.8 10.4 9.4 11.0 8.6 9.1 11.4 9.8 11.3 8.4 10.1 18.2 27.3 3.2 1.1 4.9 5.2 6.8 5.4 12.9 5.2 20.4 7.5 6.1 1.2 18.6 8.2 22.0 31.3 5.1 6.3 18.9 13.7 5.6 17.1 8.6 3.8 22.4 12.1 16.8 1.5 6.5 3.8 17.2 9.2 7.1 0.0 5.2 7.5 10.6 2.7 15.2 1.4 55.7 16.2 4.6 7.5 4.1 15.2 4.0 7.2 4.7 5.1 4.4 10.3 0.5 10.5 6.6 93.1 2.2 1.2 6.1 594.4 3.5 10.1 20.2 6.6 6.4 5.1 5.8 7.2 3.4 5.3 5.1 5.5 3.2 120.6 3.9 CLDND1 "C3orf4, Z38" ENSG00000080822 "Claudin domain containing 1" Q9NY35 3 98497912-98523066 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 1093.8;choroid plexus: 316.7" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 575.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029841 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli, Cytosol" "HPA029841: AB_10600658" "unprognostic (1.64e-1)" "unprognostic (3.63e-1)" "unprognostic (3.13e-2)" "unprognostic (8.50e-2)" "unprognostic (9.15e-2)" "unprognostic (7.30e-2)" "unprognostic (2.43e-3)" "unprognostic (4.08e-2)" "unprognostic (3.65e-2)" "unprognostic (8.30e-3)" "unprognostic (1.21e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (5.84e-6)" "unprognostic (5.73e-3)" "unprognostic (6.54e-2)" "unprognostic (3.05e-1)" "unprognostic (1.51e-1)" 53.6 42.6 477.0 40.7 757.5 49.1 48.8 696.1 804.5 59.0 316.7 58.3 36.5 58.8 43.1 77.8 46.7 50.6 57.6 483.5 577.6 39.2 50.0 46.9 54.7 851.3 670.8 63.9 23.6 32.6 28.2 73.8 837.8 49.5 46.9 46.5 29.8 51.9 43.6 64.8 42.2 63.5 643.7 44.0 37.4 106.6 638.3 44.7 40.5 68.9 54.9 64.0 65.8 1093.8 67.3 26.2 83.2 50.7 96.0 75.0 44.6 52.0 69.8 71.0 97.8 52.7 66.9 33.7 69.1 49.4 134.3 90.4 61.6 39.9 124.3 79.3 27.5 68.3 18.6 48.1 76.2 62.7 67.3 88.4 207.6 54.0 58.7 77.6 79.1 64.7 35.4 100.6 102.9 33.4 47.8 42.8 75.1 28.7 55.9 31.9 110.6 43.4 67.7 30.0 30.1 82.6 74.6 24.4 108.5 110.5 24.5 52.8 75.1 94.6 86.2 65.3 69.3 130.8 59.8 53.9 154.9 61.0 125.2 179.8 91.0 103.9 102.1 55.4 193.5 101.5 190.3 187.1 98.9 99.3 76.6 78.1 70.2 274.0 56.7 63.9 399.7 155.1 477.0 757.5 696.1 804.5 483.5 577.6 851.3 670.8 837.8 643.7 638.3 1093.8 83.3 35.3 36.6 17.9 72.1 144.0 131.7 122.3 87.0 20.1 43.6 45.3 53.8 17.2 71.4 27.6 25.0 52.0 72.8 16.9 29.4 21.2 105.3 21.1 47.7 70.8 28.7 65.4 25.1 16.2 160.6 86.6 30.1 41.7 36.8 25.2 61.4 19.4 35.6 15.2 23.6 19.6 89.5 29.2 168.1 76.7 51.6 46.9 113.8 20.6 42.3 28.1 38.1 30.7 575.2 30.3 16.8 46.6 131.7 98.1 34.6 23.3 27.5 35.0 52.6 53.2 128.4 182.4 55.3 90.1 196.5 95.8 147.1 22.8 17.5 121.9 CLDND2 MGC33839 ENSG00000160318 "Claudin domain containing 2" Q8NHS1 19 51367098-51369003 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 44.9" "Cell type enriched" "Detected in many" 9 "Early spermatids: 344.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 11.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056971 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA056971: AB_2683294" "unprognostic (2.86e-1)" "unprognostic (4.29e-5)" "unprognostic (2.29e-2)" "unprognostic (3.40e-2)" "unprognostic (1.19e-1)" "unprognostic (9.42e-2)" "unprognostic (5.74e-3)" "unprognostic (1.79e-1)" "unprognostic (2.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.25e-3)" "unprognostic (1.13e-2)" "unprognostic (1.94e-9)" "unprognostic (4.00e-2)" "unprognostic (3.95e-1)" "unprognostic (1.85e-1)" "unprognostic (8.70e-2)" 4.9 4.6 9.4 1.9 8.8 9.7 4.1 9.8 12.2 3.9 7.6 4.6 4.5 2.7 0.1 2.6 3.7 1.6 3.3 9.7 9.9 4.3 4.7 3.2 2.0 9.6 9.2 4.4 5.3 1.0 3.4 0.9 9.7 4.3 1.2 1.8 4.3 1.4 2.4 2.0 4.3 0.6 8.4 6.6 2.9 44.9 9.4 1.0 3.5 2.6 0.5 4.8 3.3 9.5 2.0 5.5 2.0 2.7 2.8 2.5 1.1 0.9 0.4 0.9 1.2 0.6 6.4 5.1 1.1 0.5 0.6 2.5 0.6 0.3 0.2 3.6 8.6 4.5 9.1 11.0 1.1 1.3 1.3 1.9 0.9 0.2 0.5 1.3 0.6 2.5 3.0 3.7 0.8 1.2 1.1 7.5 0.8 5.6 6.9 1.0 4.5 2.1 1.5 1.4 1.1 1.3 2.3 0.5 1.8 1.0 1.4 0.3 1.2 1.9 3.9 2.0 0.8 3.4 3.9 2.0 4.7 5.1 1.2 3.0 0.4 2.1 1.7 1.0 0.9 0.8 0.4 2.2 0.7 0.4 0.3 0.7 0.2 2.9 0.4 1.5 0.6 0.3 9.4 8.8 9.8 12.2 9.7 9.9 9.6 9.2 9.7 8.4 9.4 9.5 4.3 0.0 3.7 8.5 3.1 1.7 5.6 1.3 5.7 5.4 7.8 8.3 6.9 12.8 1.2 16.5 0.0 1.8 8.1 4.9 3.9 1.0 344.4 0.9 3.0 2.4 10.3 8.2 2.1 0.7 1.7 3.4 6.6 1.5 15.8 1.8 5.3 17.4 2.6 3.3 4.3 16.8 4.1 4.1 4.0 36.1 6.2 3.7 1.8 4.7 2.4 2.5 9.2 0.5 3.2 0.7 5.8 6.4 3.7 3.4 13.3 5.5 6.0 2.3 0.0 5.4 5.4 23.5 1.3 7.5 2.7 0.8 4.4 1.4 12.3 5.5 CLEC10A "CD301, CLECSF13, CLECSF14, HML, HML2" ENSG00000132514 "C-type lectin domain containing 10A" Q8IUN9 17 7074537-7080307 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Endocytosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.4" "Group enriched" "Detected in some" 6 "Langerhans cells: 805.4;Macrophages: 213.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 12 "myeloid DC: 465.9" "Lineage enriched" "Detected in many" 12 "dendritic cells: 465.9" "Not detected" "Not detected" HPA021937 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 41: Macrophages - Immune response" "HPA021937: AB_1846905" "unprognostic (3.96e-3)" "unprognostic (1.71e-3)" "unprognostic (2.95e-2)" "unprognostic (2.04e-3)" "unprognostic (4.54e-2)" "prognostic favorable (1.26e-5)" "unprognostic (1.07e-1)" "prognostic favorable (9.24e-4)" "unprognostic (2.70e-2)" "unprognostic (1.41e-1)" "unprognostic (1.12e-1)" "unprognostic (2.30e-1)" "unprognostic (6.12e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (3.23e-1)" "unprognostic (3.65e-1)" 20.9 3.3 0.3 29.4 0.4 2.5 8.5 0.3 0.6 4.1 1.6 13.6 15.8 3.8 1.2 10.4 4.5 18.8 6.4 0.3 0.4 2.7 6.9 12.3 19.8 0.4 0.5 2.1 2.8 1.3 1.3 0.7 1.2 3.0 18.2 0.0 4.3 4.7 3.0 10.0 25.5 18.9 0.3 18.5 7.7 2.5 0.6 7.8 2.6 3.1 13.6 19.9 3.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 29.9 0.1 0.0 39.0 0.2 0.0 0.2 0.1 465.9 0.3 0.1 0.0 2.1 2.2 0.3 9.2 0.3 20.5 0.3 0.4 0.3 0.6 0.3 0.4 0.4 0.5 1.2 0.3 0.6 0.5 1.1 3.2 3.9 0.0 3.6 13.3 0.0 0.0 1.2 0.0 0.2 0.5 1.2 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.1 0.1 1.5 0.0 3.0 0.2 0.0 0.2 2.0 0.0 0.1 1.3 0.0 0.4 1.1 18.4 0.0 0.0 0.1 0.0 77.9 805.4 1.2 0.3 213.9 21.4 0.0 26.9 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.9 0.0 0.0 0.2 0.0 0.0 6.6 0.5 1.7 0.0 2.3 0.4 11.8 0.1 1.6 0.0 0.0 0.0 CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725718 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 132.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 363.0;HMC-1: 637.3;NB-4: 901.1;THP-1: 694.7;U-937: 358.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "HPA042690: AB_10795511" "unprognostic (9.33e-2)" "unprognostic (6.66e-2)" "unprognostic (2.40e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.33e-1)" "unprognostic (8.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.29e-2)" "unprognostic (5.26e-2)" "unprognostic (4.99e-2)" "unprognostic (2.79e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (6.09e-2)" "unprognostic (8.66e-3)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" 17.5 17.5 5.0 7.0 5.6 132.6 14.1 7.9 9.1 44.4 2.9 12.0 4.8 31.9 1.6 8.4 37.5 6.2 16.3 4.4 7.2 21.1 12.1 15.0 2.7 10.2 7.9 31.5 7.5 2.4 22.3 5.5 8.1 22.5 1.9 0.7 6.9 4.8 4.4 16.8 9.7 8.1 7.2 14.0 8.0 9.1 6.2 2.6 12.8 1.0 0.8 19.2 28.2 6.0 2.6 3.5 0.0 2.9 33.7 45.3 79.2 139.3 37.9 15.6 15.7 0.1 0.0 0.4 1.7 70.2 0.8 1.6 0.4 0.2 10.7 0.6 22.9 363.0 0.1 0.0 21.3 0.2 637.3 33.7 0.2 1.9 2.3 0.1 17.9 16.1 4.1 2.2 29.0 2.6 3.1 901.1 1.6 0.3 4.6 30.7 0.2 0.2 0.8 0.4 0.0 3.8 4.2 0.0 58.1 0.0 0.9 694.7 100.3 1.1 41.6 0.7 0.7 2.1 2.2 0.5 47.3 358.7 44.2 1.4 24.3 0.4 0.9 11.5 0.1 0.6 0.3 0.2 17.7 0.4 2.0 4.5 1.6 5.7 5.6 4.8 0.2 8.2 5.0 5.6 7.9 9.1 4.4 7.2 10.2 7.9 8.1 7.2 6.2 6.0 12.4 3.2 5.4 10.4 3.9 32.0 32.2 2.9 27.3 20.5 30.8 31.9 3.4 8.6 4.0 29.5 10.4 8.6 5.0 1.7 119.3 11.0 6.5 17.0 70.7 16.9 26.5 36.4 9.0 3.1 72.4 107.2 4.1 14.1 5.7 18.9 51.4 6.3 49.4 21.9 8.3 4.5 10.2 21.5 73.3 19.9 70.8 29.6 78.2 9.4 11.2 70.4 14.4 8.0 12.9 3.1 1.7 67.4 0.9 21.4 0.5 13.7 5.0 20.7 65.7 20.2 59.2 17.2 21.7 26.3 45.9 18.3 5.8 56.7 3.5 17.8 CLEC16A "Gop-1, KIAA0350" ENSG00000038532 "C-type lectin domain containing 16A" Q2KHT3 16 10944564-11182186 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 130.9;Early spermatids: 118.7;Excitatory neurons: 93.3;Inhibitory neurons: 135.1;Late spermatids: 84.8;Oligodendrocyte precursor cells: 69.4;Oligodendrocytes: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HDLM-2: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035814, HPA035815, HPA061385" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 43: Testis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "HPA035814: AB_10600801, HPA035815: AB_10671937, HPA061385: AB_2684498" "unprognostic (3.41e-1)" "unprognostic (4.58e-2)" "unprognostic (7.36e-2)" "unprognostic (1.56e-2)" "unprognostic (3.44e-1)" "unprognostic (1.33e-2)" "unprognostic (3.44e-1)" "unprognostic (2.22e-3)" "unprognostic (4.54e-2)" "unprognostic (7.78e-3)" "unprognostic (2.08e-1)" "unprognostic (3.49e-1)" "prognostic favorable (2.92e-6)" "unprognostic (2.69e-1)" "unprognostic (1.79e-1)" "unprognostic (8.22e-2)" "unprognostic (3.03e-1)" 10.2 12.8 12.1 7.2 13.4 13.2 9.4 16.7 17.3 11.2 23.6 9.5 8.2 9.0 6.9 13.9 9.4 4.8 14.6 11.3 11.1 16.6 16.2 12.8 9.3 13.8 14.5 8.2 8.9 11.7 17.3 7.0 13.8 11.3 5.9 11.5 9.1 5.7 17.5 14.2 10.8 6.2 9.7 12.4 10.4 46.8 21.0 10.9 13.3 8.3 8.8 9.1 10.4 11.7 11.6 12.1 9.0 11.9 14.8 10.3 8.0 11.7 11.4 9.6 12.5 13.5 21.1 22.8 26.6 14.3 10.6 10.1 11.6 21.7 12.3 110.3 12.5 10.4 16.4 14.4 10.4 11.5 21.5 12.3 10.4 15.9 13.4 8.8 13.3 12.4 17.6 13.8 11.5 19.0 18.2 9.1 7.2 10.0 9.5 24.6 7.6 13.5 20.1 8.4 11.5 15.3 16.8 17.1 9.1 10.4 12.1 17.7 14.2 12.4 16.1 18.3 10.4 9.7 9.2 18.7 15.5 16.4 13.1 2.7 1.9 1.4 2.2 1.5 1.3 1.7 1.8 1.5 1.5 2.8 2.1 1.8 2.6 1.8 3.0 2.0 1.4 1.1 12.1 13.4 16.7 17.3 11.3 11.1 13.8 14.5 13.8 9.7 21.0 11.7 7.1 16.0 10.0 130.9 12.8 7.1 3.7 5.9 11.4 11.7 5.2 5.1 5.9 8.6 8.8 3.7 37.5 3.4 5.5 12.1 0.0 6.0 118.7 7.5 6.0 6.1 7.7 8.6 93.3 6.4 2.6 6.2 9.2 8.0 8.2 5.7 9.7 12.6 4.8 11.8 135.1 7.9 6.1 5.4 6.2 84.8 5.6 6.8 3.6 40.3 8.6 3.9 4.1 69.4 72.9 6.5 4.0 8.6 8.8 3.5 10.3 3.5 8.9 18.3 0.0 7.4 4.5 27.1 8.4 13.4 8.2 3.8 8.6 3.3 6.7 4.9 CLEC18A MRCL ENSG00000157322 "C-type lectin domain family 18 member A" A5D8T8 16 69950705-69964452 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 23.9" "Cell type enriched" "Detected in some" 23 "Proximal tubular cells: 78.0" "Cancer enriched" "Detected in single" 7 "renal cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048976 Uncertain "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA048976: AB_2680582" "unprognostic (1.68e-1)" "unprognostic (3.06e-2)" "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (3.14e-2)" "unprognostic (4.62e-2)" "unprognostic (1.36e-1)" "unprognostic (4.14e-2)" "unprognostic (1.04e-1)" "unprognostic (4.40e-2)" "unprognostic (6.77e-4)" "unprognostic (6.73e-2)" "unprognostic (4.58e-2)" "unprognostic (2.06e-1)" "unprognostic (9.03e-4)" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" 0.2 0.9 0.1 0.0 0.2 0.3 0.3 0.6 0.5 0.3 2.8 0.4 0.0 0.1 0.0 0.1 0.3 0.1 0.1 0.2 0.2 23.9 0.2 0.4 0.1 0.2 0.2 0.2 0.4 0.1 0.4 0.0 0.4 0.3 0.1 0.1 0.6 0.0 0.2 0.3 0.7 0.0 0.2 1.2 0.5 3.2 0.2 0.3 0.4 0.1 0.1 0.3 0.1 0.3 0.0 0.1 0.7 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.5 0.2 0.2 0.2 0.2 0.4 0.2 0.2 0.3 0.3 0.0 1.1 0.0 0.9 0.1 0.0 0.2 0.0 1.6 0.3 0.4 0.5 2.8 0.4 0.0 2.1 0.1 0.3 3.3 1.9 0.3 0.4 0.4 0.1 0.4 0.0 0.0 0.3 0.2 0.1 0.3 2.0 0.5 0.0 0.6 2.5 0.4 0.4 3.3 0.4 1.0 0.0 0.6 0.3 0.8 0.3 1.1 0.0 0.0 0.9 0.9 1.0 0.0 0.0 0.5 0.4 0.0 0.2 0.2 1.5 78.0 0.7 1.3 0.0 0.7 1.3 0.5 0.2 0.0 0.0 0.3 0.6 0.6 1.3 0.2 CLEC18B MRCL2 ENSG00000140839 "C-type lectin domain family 18 member B" Q6UXF7 16 74408270-74421953 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 33.4;testis: 11.8" "Cell type enriched" "Detected in some" 14 "Proximal tubular cells: 26.8" "Cancer enhanced" "Detected in some" "glioma: 2.7;renal cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.1;JURKAT: 1.6;K-562: 3.1;U-266/70: 1.1" HPA048976 Uncertain "Secreted to blood" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA048976: AB_2680582" "unprognostic (5.69e-2)" "unprognostic (1.46e-1)" "unprognostic (5.30e-3)" "unprognostic (9.37e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (7.15e-2)" "unprognostic (7.51e-2)" "unprognostic (4.49e-3)" "unprognostic (2.17e-1)" "unprognostic (2.28e-1)" "unprognostic (9.91e-2)" "unprognostic (3.58e-2)" "unprognostic (1.42e-2)" "unprognostic (2.31e-2)" "unprognostic (5.87e-2)" "unprognostic (5.43e-2)" "unprognostic (4.27e-2)" 0.1 1.9 3.4 0.4 3.7 0.1 0.2 4.5 4.9 0.5 2.6 0.2 0.4 0.1 0.6 2.7 0.3 0.3 0.2 3.8 3.8 33.4 0.6 0.2 0.1 3.7 3.6 0.2 0.6 0.0 0.8 0.1 4.0 0.5 0.1 2.3 0.6 0.0 0.2 0.2 0.3 0.1 3.6 0.6 0.3 11.8 3.3 0.2 0.6 0.0 0.0 0.1 1.7 4.4 0.0 0.6 1.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.2 0.2 0.4 0.4 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.6 0.1 0.0 0.0 0.2 0.0 1.6 3.1 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.3 0.1 0.0 0.6 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.3 1.1 0.7 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.7 4.5 4.9 3.8 3.8 3.7 3.6 4.0 3.6 3.3 4.4 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.5 1.9 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.0 1.6 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.5 0.1 0.0 0.0 0.0 0.4 26.8 0.0 1.4 0.0 0.0 0.2 0.5 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 CLEC18C "MGC34761, MRCL3" ENSG00000157335 "C-type lectin domain family 18 member C" Q8NCF0 16 70173322-70187361 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 17.8" "Cell type enriched" "Detected in single" 46 "Proximal tubular cells: 23.3" "Cancer enriched" "Detected in single" 9 "renal cancer: 1.4" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048976 Uncertain "Secreted to blood" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA048976: AB_2680582" "unprognostic (3.90e-1)" "unprognostic (3.03e-1)" "unprognostic (1.20e-4)" "unprognostic (5.55e-2)" "unprognostic (5.72e-3)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (3.79e-2)" "unprognostic (3.61e-3)" "unprognostic (6.98e-2)" 0.0 0.1 0.1 0.0 0.3 0.0 0.0 1.0 0.5 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 17.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.5 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 CLEC19A ENSG00000261210 "C-type lectin domain containing 19A" Q6UXS0 16 19285731-19322145 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.7" "Group enriched" "Detected in some" 4 "Microglial cells: 6.5;Respiratory ciliated cells: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.19e-1)" "unprognostic (3.72e-1)" "unprognostic (1.11e-1)" "unprognostic (1.82e-2)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" 0.0 0.0 2.5 0.0 1.8 0.0 0.0 1.2 2.7 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.8 1.2 2.7 2.2 0.2 0.0 0.7 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 CLEC20A "FLJ44005, LINC00083, NCRNA00083, RP4-593C16.2" ENSG00000188585 "C-type lectin domain containing 20A" Q6ZU45 1 178479247-178499634 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.2;testis: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 3.2;naive B-cell: 10.7" "Lineage enriched" "Detected in many" 6 "B-cells: 10.7" "Cell line enriched" "Detected in single" 5 "REH: 1.0" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 2.1 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.3 10.7 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CLEC2B "AICL, CLECSF2, HP10085" ENSG00000110852 "C-type lectin domain family 2 member B" Q92478 12 9852369-9869386 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 113.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 393.1;dendritic cells: 255.7;NK-cells: 265.7;Suprabasal keratinocytes: 240.8;T-cells: 276.6" "Cancer enhanced" "Detected in all" "cervical cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 221.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 56.7;ASC TERT1: 87.7;fHDF/TERT166: 49.5;HSkMC: 50.3;U-937: 229.5" "Low region specificity" "Detected in all" HPA008194 Enhanced "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA008194: AB_1078533" "unprognostic (3.14e-2)" "unprognostic (4.27e-2)" "unprognostic (2.14e-2)" "unprognostic (9.69e-3)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" "unprognostic (5.99e-2)" "unprognostic (4.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.58e-1)" "unprognostic (1.15e-3)" "unprognostic (3.50e-1)" "prognostic unfavorable (5.64e-13)" "unprognostic (8.09e-2)" "unprognostic (7.12e-3)" "unprognostic (5.70e-2)" "unprognostic (2.79e-1)" 32.4 7.4 10.7 21.9 10.8 113.0 23.5 13.1 20.0 23.1 12.5 9.4 7.2 19.9 6.5 17.4 15.5 20.5 14.6 10.7 10.4 8.2 16.3 39.3 32.2 12.2 11.2 33.1 2.5 2.9 4.2 17.6 12.3 9.8 13.5 2.4 12.7 6.0 17.2 80.0 14.0 14.5 11.2 44.7 9.1 3.0 12.8 16.3 10.4 20.6 16.0 19.8 23.9 11.8 0.3 2.6 0.0 0.2 56.7 87.7 0.4 1.6 11.0 0.8 2.9 0.1 1.8 1.2 0.9 49.5 32.8 17.4 8.0 0.1 0.2 1.8 0.1 2.3 0.1 0.1 19.9 2.0 0.4 50.3 18.1 2.2 0.4 2.9 29.1 9.0 0.1 7.4 13.0 0.1 15.2 4.1 0.3 0.0 2.0 20.9 0.4 0.1 0.1 18.3 0.1 0.0 0.8 0.2 13.9 0.2 3.6 0.6 41.8 0.4 9.2 1.6 5.3 13.2 1.2 1.7 13.5 229.5 16.8 54.8 37.8 14.6 68.2 58.1 55.4 12.6 42.3 69.7 34.5 20.0 40.2 62.2 221.4 67.2 75.6 12.6 36.0 84.4 10.7 10.8 13.1 20.0 10.7 10.4 12.2 11.2 12.3 11.2 12.8 11.8 216.3 3.2 23.1 0.0 102.0 201.6 76.4 393.1 106.4 0.1 4.4 7.7 3.6 7.2 122.3 0.0 0.0 0.9 255.7 0.5 0.0 5.1 0.3 5.8 84.2 179.5 1.8 32.8 0.0 0.8 2.0 97.1 3.6 5.5 54.4 1.3 142.8 3.6 74.4 0.0 0.0 1.0 61.1 141.5 208.2 2.4 49.7 183.2 80.0 15.0 59.2 1.1 265.7 0.0 0.2 1.9 0.0 17.7 102.8 23.9 0.3 1.1 17.4 0.7 6.6 45.8 26.4 0.3 0.5 99.9 240.8 1.9 276.6 16.7 1.1 140.9 CLEC2D "CLAX, LLT1, OCIL" ENSG00000069493 "C-type lectin domain family 2 member D" Q9UHP7 12 9664969-9699553 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 53.5" "Cell type enhanced" "Detected in many" "B-cells: 128.6;dendritic cells: 112.0;Early spermatids: 95.5;monocytes: 81.6;NK-cells: 131.8;T-cells: 215.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "gdT-cell: 188.1;MAIT T-cell: 114.5;memory B-cell: 95.0;memory CD4 T-cell: 183.3;memory CD8 T-cell: 208.7;naive B-cell: 127.5;naive CD4 T-cell: 192.3;naive CD8 T-cell: 223.0;T-reg: 175.2" "Group enriched" "Detected in all" 11 "B-cells: 127.5;T-cells: 223.0" "Group enriched" "Detected in many" 4 "Daudi: 67.9;HDLM-2: 53.3;Karpas-707: 31.0;U-698: 105.8" "HPA017649, HPA047584" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "HPA017649: AB_1846912, HPA047584: " "unprognostic (1.09e-3)" "prognostic favorable (1.37e-4)" "unprognostic (1.16e-1)" "unprognostic (4.27e-2)" "unprognostic (1.29e-1)" "unprognostic (2.77e-4)" "unprognostic (4.34e-2)" "unprognostic (1.72e-3)" "unprognostic (1.24e-2)" "unprognostic (1.92e-1)" "unprognostic (6.87e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (5.85e-11)" "unprognostic (1.17e-1)" "unprognostic (2.70e-1)" "unprognostic (3.44e-1)" "prognostic favorable (1.68e-7)" 6.1 1.8 3.6 16.7 3.5 16.0 5.6 3.3 4.9 6.4 3.1 4.8 3.3 4.5 11.8 3.2 5.3 5.5 5.3 3.2 3.7 3.9 2.9 8.6 53.5 4.0 3.4 6.0 2.4 0.8 2.3 2.6 3.9 7.3 3.9 2.2 6.5 4.5 2.9 3.7 20.3 2.0 3.5 26.6 5.5 9.5 4.1 31.6 4.5 1.3 41.7 5.7 4.6 4.2 1.2 2.5 3.5 0.3 0.5 1.4 4.0 1.7 2.5 0.6 2.1 1.9 2.1 67.9 0.3 1.8 1.0 0.7 1.2 0.2 1.1 53.3 0.9 2.1 1.6 2.9 5.7 1.7 1.7 2.3 1.7 0.5 2.1 8.0 0.1 1.2 0.5 31.0 1.5 4.5 0.7 5.9 3.2 0.2 0.4 14.9 1.6 2.2 3.4 3.6 0.6 1.3 0.9 2.8 3.0 6.6 0.6 1.8 0.6 1.3 1.8 1.0 1.2 4.4 1.1 105.8 2.8 3.1 2.1 6.8 2.1 1.5 188.1 1.4 114.5 95.0 183.3 208.7 2.3 127.5 192.3 223.0 6.0 16.5 1.3 1.6 175.2 109.8 3.6 3.5 3.3 4.9 3.2 3.7 4.0 3.4 3.9 3.5 4.1 4.2 8.9 6.4 20.7 11.8 128.6 4.1 39.7 2.1 1.8 1.3 6.5 6.1 9.6 4.3 7.1 1.8 4.2 10.4 112.0 0.8 7.9 3.0 95.5 3.6 6.9 13.0 0.0 21.5 6.3 1.9 6.0 12.2 4.6 6.2 20.2 18.1 12.5 2.3 9.2 5.0 6.8 2.5 0.0 20.9 17.8 28.3 8.4 19.4 1.8 56.2 81.6 3.2 131.8 27.6 4.4 2.8 2.0 9.8 71.5 17.2 0.5 2.1 7.4 2.3 19.7 26.2 8.7 5.7 6.3 1.9 4.8 4.8 215.1 7.4 3.5 24.3 CLEC3A CLECSF1 ENSG00000166509 "C-type lectin domain family 3 member A" O75596 16 78022515-78066761 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;breast: 9.3;urinary bladder: 5.8" "Cell type enriched" "Detected in single" 7 "Prostatic glandular cells: 4.7" "Cancer enriched" "Detected in some" 102 "breast cancer: 78.5" "Region enriched" "Detected in single" 6 "midbrain: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SK-BR-3: 7.4;T-47d: 21.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA051511 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 5: Breast - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 22: Epithelial cell types - Mixed function" "HPA051511: AB_2681514" "prognostic unfavorable (1.61e-4)" "unprognostic (1.60e-1)" "unprognostic (2.42e-1)" "unprognostic (1.25e-1)" "unprognostic (4.95e-2)" "unprognostic (3.80e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.2 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 5.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 4.2 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CLEC3B "TN, TNA" ENSG00000163815 "C-type lectin domain family 3 member B" P05452 3 45001548-45036071 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 420.3" "Cell type enhanced" "Detected in some" "Adipocytes: 76.3;Endothelial cells: 27.9;Fibroblasts: 126.4;Hepatic stellate cells: 57.5;Leydig cells: 30.1;Microglial cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 297.9;ASC TERT1: 591.9;U-2197: 120.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002582, HPA034794" Approved "Secreted to blood" NA NA 6540000000 25000000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB002582: AB_564027, HPA034794: AB_2674332" "unprognostic (2.04e-1)" "unprognostic (1.80e-3)" "unprognostic (2.58e-1)" "unprognostic (4.57e-2)" "unprognostic (7.75e-2)" "prognostic favorable (1.53e-4)" "prognostic favorable (9.99e-9)" "unprognostic (1.75e-2)" "unprognostic (2.25e-1)" "unprognostic (4.02e-1)" "prognostic favorable (5.68e-4)" "unprognostic (9.33e-2)" "unprognostic (2.39e-2)" "unprognostic (7.46e-2)" "unprognostic (1.39e-1)" "unprognostic (5.54e-2)" "unprognostic (4.21e-2)" 420.3 51.0 44.4 9.3 46.4 1.7 214.8 45.5 66.6 89.4 50.9 83.9 31.6 60.4 17.1 49.9 41.1 35.6 259.9 43.0 42.9 131.4 29.0 201.2 33.1 51.3 56.1 26.0 14.6 14.3 27.7 142.8 48.0 33.5 37.4 0.7 49.8 19.1 74.8 149.7 78.2 25.5 44.8 264.5 43.5 113.2 50.7 10.1 88.4 68.0 8.2 100.9 74.9 43.0 0.0 0.0 0.1 0.2 297.9 591.9 0.0 40.1 62.9 1.2 6.2 0.0 0.0 0.1 0.1 3.1 0.0 0.1 0.0 0.1 0.1 0.3 0.9 0.6 0.1 0.1 0.5 0.1 0.7 47.5 0.1 0.3 0.1 0.4 0.5 0.3 0.0 1.7 0.5 0.2 0.0 2.2 0.0 0.0 0.6 0.0 0.1 2.2 0.0 0.0 0.3 1.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 4.5 0.2 120.6 0.1 1.0 1.2 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.4 46.4 45.5 66.6 43.0 42.9 51.3 56.1 48.0 44.8 50.7 43.0 76.3 0.0 0.0 1.6 0.3 3.4 0.0 0.0 1.8 0.0 0.7 0.3 0.8 1.5 0.0 0.0 0.0 0.0 0.5 0.0 3.9 0.0 4.0 0.3 16.9 27.9 0.0 2.7 0.8 0.2 0.0 126.4 3.1 0.3 0.0 0.0 57.5 0.3 0.9 0.0 0.6 0.0 0.0 1.2 9.5 19.5 30.1 2.2 3.6 69.3 0.7 0.4 0.0 1.5 0.7 0.1 0.0 6.4 0.5 0.0 0.0 0.0 0.0 0.3 0.0 1.0 12.3 0.0 0.0 0.7 3.8 0.1 0.7 0.4 0.0 0.0 CLEC4C "BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL" ENSG00000198178 "C-type lectin domain family 4 member C" Q8WTT0 12 7729383-7751605 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.5" "Cell type enriched" "Detected in some" 21 "dendritic cells: 107.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 16 "plasmacytoid DC: 468.0" "Lineage enriched" "Detected in many" 16 "dendritic cells: 468.0" "Cell line enriched" "Detected in single" 5 "HDLM-2: 2.1" HPA029432 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA029432: AB_10601259" "unprognostic (3.55e-3)" "unprognostic (3.01e-2)" "unprognostic (1.03e-1)" "unprognostic (3.70e-2)" "unprognostic (7.37e-5)" "unprognostic (2.36e-2)" "unprognostic (2.06e-1)" "unprognostic (2.55e-2)" "unprognostic (6.98e-2)" "unprognostic (1.39e-1)" "unprognostic (1.88e-3)" "unprognostic (2.82e-2)" "unprognostic (3.18e-3)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" 0.3 0.1 0.0 1.4 0.1 1.6 1.4 0.4 0.2 0.1 0.7 0.1 0.0 0.1 0.0 0.2 0.1 1.2 0.0 0.1 0.0 0.1 0.2 0.6 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 3.8 0.2 0.9 0.0 2.1 0.1 0.0 5.2 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 5.3 0.7 30.0 0.1 0.1 0.1 0.6 0.1 0.1 4.1 2.6 0.1 0.0 14.7 2.9 0.0 468.0 0.2 3.0 0.0 0.1 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 107.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.0 0.1 0.0 1.9 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 4.9 0.0 0.3 0.0 0.8 0.0 0.0 0.0 CLEC4D "CD368, CLECSF8, Dectin-3, MCL, Mpcl" ENSG00000166527 "C-type lectin domain family 4 member D" Q8WXI8 12 8509475-8522366 "CD markers, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 64.7" "Group enriched" "Detected in some" 5 "Kupffer cells: 10.6;Macrophages: 11.9;monocytes: 15.1" "Cancer enriched" "Detected in single" 50 "testis cancer: 11.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "classical monocyte: 57.1;neutrophil: 98.7" "Group enriched" "Detected in many" 32 "granulocytes: 98.7;monocytes: 57.1" "Group enriched" "Detected in some" 5 "NB-4: 2.4;NTERA-2: 9.0;SuSa: 9.1;U-937: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA004906 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA004906: AB_1078535" "unprognostic (1.10e-1)" "unprognostic (4.94e-2)" "unprognostic (4.78e-2)" "unprognostic (1.27e-1)" "unprognostic (4.39e-1)" "unprognostic (3.84e-2)" "unprognostic (7.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.70e-1)" "unprognostic (3.81e-1)" "unprognostic (7.91e-5)" "unprognostic (1.12e-2)" "unprognostic (8.57e-2)" "unprognostic (7.89e-2)" "unprognostic (2.18e-1)" 2.3 0.2 0.0 7.3 0.1 64.7 0.2 0.0 0.2 3.1 0.3 0.1 0.1 0.1 0.5 0.4 0.7 0.4 0.3 0.0 0.0 0.2 0.5 3.1 0.6 0.1 0.1 0.0 0.5 0.0 0.0 0.7 0.1 0.1 0.1 0.6 0.4 0.0 0.1 0.0 0.2 0.8 0.0 7.0 0.2 0.2 0.4 0.3 0.1 0.7 0.3 2.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 9.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.9 57.1 0.0 0.0 4.5 0.0 0.3 0.0 0.1 2.4 0.0 0.0 0.1 98.7 0.0 1.2 0.7 0.0 12.4 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.6 0.8 0.0 0.0 11.9 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 CLEC4E "CLECSF9, mincle" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.7;lymphoid tissue: 52.3" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 31.9;Kupffer cells: 158.0;Macrophages: 115.2;monocytes: 109.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "classical monocyte: 128.8;neutrophil: 448.8" "Group enriched" "Detected in many" 17 "granulocytes: 448.8;monocytes: 128.8" "Group enriched" "Detected in some" 4 "NB-4: 4.3;RPTEC TERT1: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain Uncertain Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA004935: AB_2667299" "unprognostic (3.05e-2)" "unprognostic (2.01e-2)" "unprognostic (8.91e-2)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (9.71e-3)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.62e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (2.29e-1)" 13.3 5.4 2.3 37.5 2.1 75.7 4.5 1.8 4.4 5.8 2.2 2.2 0.4 2.3 0.4 3.2 5.5 11.8 2.5 2.3 2.9 3.6 6.6 22.4 7.6 1.3 1.3 1.7 6.2 1.7 1.9 2.1 1.2 2.3 1.0 1.3 1.4 1.2 0.7 0.9 3.1 5.7 0.7 52.3 2.5 1.1 2.0 2.2 10.5 5.0 2.3 9.6 1.7 2.9 0.1 0.4 0.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.1 0.1 2.0 0.0 0.1 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.5 0.1 0.0 1.5 0.0 0.5 0.2 0.2 0.2 0.2 0.0 0.1 0.0 4.3 0.3 0.0 0.0 0.0 0.2 0.1 12.4 0.1 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.4 1.0 0.5 0.1 1.0 0.1 0.2 0.1 0.1 1.3 0.4 0.1 0.2 128.8 0.5 0.1 18.1 0.3 0.1 0.1 0.1 16.9 0.1 0.0 0.1 448.8 0.0 0.7 0.7 0.0 30.3 2.3 2.1 1.8 4.4 2.3 2.9 1.3 1.3 1.2 0.7 2.0 2.9 6.2 0.0 4.7 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 5.7 1.8 1.8 0.0 0.0 0.3 0.0 0.0 9.0 0.3 2.1 4.4 3.5 0.0 0.0 0.0 0.0 0.1 1.4 0.0 31.9 0.0 0.0 7.1 2.1 5.6 0.0 0.0 0.0 0.0 158.0 9.0 2.9 0.9 115.2 0.0 0.0 109.5 0.0 4.1 0.0 0.0 0.4 0.0 0.4 1.3 0.0 0.0 0.2 0.7 0.0 13.1 0.2 0.4 0.2 0.5 0.1 0.0 0.1 1.1 0.0 0.0 0.1 CLEC4G "LSECtin, UNQ431" ENSG00000182566 "C-type lectin domain family 4 member G" Q6UXB4 19 7728958-7733906 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 14.9;liver: 53.3;lymphoid tissue: 15.1" "Cell type enriched" "Detected in some" 15 "Hepatic stellate cells: 730.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 18.8;myeloid DC: 15.1" "Group enriched" "Detected in many" 4 "dendritic cells: 15.1;monocytes: 18.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003789, HPA014044" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB003789: , HPA014044: AB_1846916" "unprognostic (7.20e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.64e-1)" "unprognostic (4.47e-2)" "unprognostic (1.35e-1)" "unprognostic (7.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.23e-1)" "unprognostic (3.29e-2)" "unprognostic (7.45e-2)" "unprognostic (3.04e-1)" "unprognostic (2.13e-8)" "unprognostic (5.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (6.65e-2)" 14.9 0.5 1.9 2.4 1.9 1.2 2.6 4.0 2.9 0.1 2.0 1.4 0.4 0.1 0.3 0.4 4.8 1.6 1.2 2.5 1.9 0.5 53.3 1.0 15.1 2.3 2.1 0.5 0.3 0.0 0.1 1.0 2.1 0.3 0.9 0.0 1.1 0.3 0.4 1.1 2.0 1.0 2.1 3.4 0.9 0.4 4.3 0.2 0.5 0.0 0.3 7.7 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.8 0.0 0.0 4.2 0.0 0.3 0.0 0.0 15.1 4.2 0.1 0.0 0.4 0.5 0.5 0.7 0.0 4.5 1.9 1.9 4.0 2.9 2.5 1.9 2.3 2.1 2.1 2.1 4.3 2.1 0.1 0.0 0.0 0.3 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 18.7 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 730.3 7.1 0.8 0.0 1.1 0.0 0.0 46.7 2.9 0.0 0.3 2.6 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.7 0.0 0.3 0.3 1.1 0.8 0.0 0.1 CLEC4M "CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, LSIGN" ENSG00000104938 "C-type lectin domain family 4 member M" Q9H2X3 19 7763210-7769605 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 62.6;lymphoid tissue: 16.4" "Cell type enriched" "Detected in some" 11 "Hepatic stellate cells: 270.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033689, CAB033691, HPA042661" Supported "Intracellular and membrane" NA NA 3400000 "Cluster 43: B-cells - Humoral immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB033689: AB_831088, CAB033691: AB_2081354, HPA042661: AB_2678101" "unprognostic (1.56e-1)" "unprognostic (3.03e-1)" "unprognostic (1.00e-1)" "unprognostic (1.71e-2)" "unprognostic (1.26e-2)" "unprognostic (1.64e-1)" "unprognostic (6.58e-2)" "unprognostic (1.27e-1)" "unprognostic (4.58e-3)" "unprognostic (4.60e-2)" "unprognostic (5.15e-2)" "unprognostic (1.43e-1)" 1.4 1.1 0.0 0.3 0.0 0.1 0.2 0.2 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 62.6 3.2 16.4 0.8 0.6 3.0 0.1 0.0 0.1 7.3 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.3 0.4 0.0 2.2 0.2 0.0 0.1 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.8 0.6 0.5 0.3 0.2 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.5 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 3.5 0.0 18.7 0.1 0.0 0.0 1.3 0.0 0.0 0.0 15.7 270.2 2.8 0.7 0.0 0.2 0.0 0.0 14.8 2.3 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.8 1.4 0.1 0.0 0.0 0.3 0.3 23.4 0.0 0.2 CLGN ENSG00000153132 Calmegin O14967 4 140388453-140427661 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 59.5;testis: 113.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 313.3;Early spermatids: 162.4;Endometrial ciliated cells: 93.4;Muller glia cells: 176.4;Spermatocytes: 465.5" "Cancer enhanced" "Detected in many" "prostate cancer: 19.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 53.0;MOLT-4: 47.8;U-251 MG: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020709, HPA048761, HPA058627" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 43: Testis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "CAB020709: , HPA048761: AB_2680514, HPA058627: AB_2683782" "unprognostic (6.74e-2)" "unprognostic (8.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" "unprognostic (3.73e-3)" "unprognostic (6.14e-2)" "unprognostic (4.80e-2)" "unprognostic (3.11e-1)" "unprognostic (5.38e-3)" "unprognostic (2.29e-2)" "unprognostic (2.45e-3)" "unprognostic (3.00e-3)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.01e-1)" 0.4 6.6 0.9 1.0 0.7 2.4 2.7 3.8 1.6 0.9 2.0 2.6 0.5 1.6 0.6 1.2 13.7 0.4 59.5 0.9 2.6 0.4 3.2 0.5 0.7 2.7 1.9 0.3 2.2 0.6 11.2 0.2 2.6 22.5 1.3 17.2 1.0 0.7 0.4 0.2 1.3 1.5 1.2 0.2 2.0 113.6 2.3 2.4 2.7 1.6 1.2 0.6 0.1 0.9 0.2 10.2 10.3 6.9 4.0 21.1 2.4 0.1 9.4 10.0 18.6 0.3 0.9 0.0 27.8 0.9 8.4 0.2 7.5 0.1 16.2 0.4 9.0 3.0 9.8 7.4 41.4 38.9 0.6 2.2 39.2 1.0 0.9 53.0 0.2 9.6 2.0 0.0 0.0 0.5 47.8 0.5 12.0 0.2 28.1 31.5 0.0 0.4 0.0 0.3 16.8 29.8 6.5 4.1 1.8 3.8 1.9 5.6 0.0 27.4 4.7 9.7 73.6 14.4 31.7 19.9 43.4 1.6 2.9 0.9 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 3.8 1.6 0.9 2.6 2.7 1.9 2.6 1.2 2.3 0.9 0.8 0.0 2.2 0.3 0.1 0.0 0.9 8.5 1.2 9.2 3.3 1.8 313.3 0.0 6.4 0.0 4.2 0.5 0.0 0.5 0.0 1.2 162.4 93.4 1.3 11.9 5.3 8.6 7.2 4.2 0.1 10.2 0.0 11.3 0.0 10.1 0.7 3.7 0.1 25.2 6.7 0.4 30.5 0.0 0.0 60.2 5.0 0.7 1.8 0.0 0.1 176.4 0.0 6.6 0.6 0.9 3.9 4.5 0.1 33.8 0.2 0.1 24.6 16.3 0.0 0.6 2.0 465.5 23.9 2.8 0.1 0.3 0.7 0.2 0.8 1.3 CLN5 ENSG00000102805 "CLN5 intracellular trafficking protein" O75503 13 76990660-77019143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 128.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041788 Approved "Intracellular and membrane" NA NA 470000 "Cluster 2: Granulocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA041788: AB_10962726" "unprognostic (1.19e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.02e-1)" "unprognostic (9.82e-2)" "unprognostic (2.07e-3)" "unprognostic (3.41e-1)" "unprognostic (7.80e-2)" "unprognostic (2.29e-1)" "unprognostic (2.90e-1)" "unprognostic (6.98e-2)" "unprognostic (2.65e-1)" "prognostic favorable (1.52e-9)" "unprognostic (2.35e-1)" "unprognostic (7.04e-2)" "unprognostic (5.64e-2)" "unprognostic (8.15e-2)" 20.9 19.8 13.9 14.4 12.8 13.3 21.8 27.0 18.9 25.1 17.0 16.1 11.3 19.1 41.9 10.9 24.5 25.2 14.2 13.5 10.5 50.5 35.5 20.5 19.8 12.5 11.6 26.6 16.8 45.6 14.4 23.3 12.2 22.3 16.5 24.1 21.4 22.7 8.4 14.6 13.6 15.9 7.0 16.7 18.8 16.1 13.0 18.3 72.9 10.7 18.5 18.8 12.0 19.0 25.0 11.7 16.4 13.7 74.4 48.5 21.1 23.7 43.3 18.4 31.9 12.3 23.2 9.7 17.3 33.5 21.0 25.0 11.5 25.5 20.0 18.4 21.5 13.9 13.1 12.2 33.8 19.5 20.4 43.6 28.4 8.9 18.7 37.1 33.0 13.5 9.4 17.2 43.2 7.7 11.6 12.5 10.7 48.6 10.4 9.5 14.4 9.0 42.6 13.8 7.3 11.3 14.1 17.4 26.3 21.3 19.0 26.0 31.2 13.2 10.4 15.4 14.2 21.7 30.0 12.2 35.4 13.5 29.2 58.4 15.6 39.4 3.5 22.4 3.1 13.2 17.0 6.0 10.8 14.5 21.5 13.3 11.4 1.0 27.7 11.0 25.6 14.1 13.9 12.8 27.0 18.9 13.5 10.5 12.5 11.6 12.2 7.0 13.0 19.0 30.5 16.0 32.4 16.6 29.2 11.5 32.5 75.1 17.1 19.8 22.3 20.2 8.7 25.8 59.2 68.0 10.4 53.2 15.2 24.0 9.8 39.3 1.6 26.6 25.0 24.1 13.8 7.8 9.7 38.4 128.5 36.9 13.3 24.8 22.2 23.5 25.7 33.0 48.1 6.7 12.6 13.6 97.6 22.4 16.7 4.5 49.7 22.7 24.9 11.2 31.5 50.4 5.2 15.6 21.5 25.0 14.4 47.4 18.8 23.1 23.9 44.1 48.2 25.4 19.7 24.4 27.2 25.8 34.7 14.6 11.5 46.4 15.2 34.0 11.4 21.8 CLPS ENSG00000137392 Colipase P04118 6 35794982-35797344 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Digestion, Lipid degradation, Lipid metabolism" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1696 "pancreas: 262086.0" "Cell type enriched" "Detected in some" 17 "Exocrine glandular cells: 23175.0" "Cancer enriched" "Detected in many" 188 "pancreatic cancer: 1726.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA010512 Enhanced "Secreted to digestive system" NA NA 1600000 "Cluster 15: NK-cells - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" "HPA010512: AB_1846979" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (8.12e-3)" "unprognostic (2.47e-1)" "unprognostic (1.33e-1)" "unprognostic (1.61e-1)" 30.4 6.1 0.9 5.8 1.8 9.0 17.8 0.1 0.7 13.4 0.2 6.8 40.2 6.0 5.6 9.9 3.8 0.0 46.3 1.2 0.1 5.5 17.7 4.1 10.5 0.2 0.2 154.4 262086.0 0.0 6.3 11.9 0.3 7.9 0.0 0.0 41.7 0.0 5.8 8.1 24.0 0.0 0.1 7.9 27.7 4.0 0.6 0.0 3.8 0.0 0.0 3.3 5.1 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.6 0.3 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.9 1.8 0.1 0.7 1.2 0.1 0.2 0.2 0.3 0.1 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.6 0.0 0.0 0.0 1.1 11.9 0.0 0.0 23175.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 130.8 0.0 0.0 0.0 0.0 1331.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CLPSL1 "C6orf127, dJ510O8.6" ENSG00000204140 "Colipase like 1" A2RUU4 6 35781019-35793675 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 90 "epididymis: 607.6;pancreas: 178.4" "Cell type enriched" "Detected in some" 4 "Exocrine glandular cells: 39.0" "Group enriched" "Detected in some" 6 "breast cancer: 3.6;cervical cancer: 1.0;endometrial cancer: 2.8;ovarian cancer: 1.8;pancreatic cancer: 3.4" "Group enriched" "Detected in many" 4 "amygdala: 1.1;basal ganglia: 2.5;cerebral cortex: 2.3;hippocampal formation: 2.9;white matter: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 17 "T-47d: 8.4" HPA073155 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 1: Pancreatic cells - Digestion" "HPA073155: AB_2686576" "unprognostic (7.97e-2)" "unprognostic (1.58e-1)" "unprognostic (4.75e-1)" "unprognostic (2.54e-1)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.60e-2)" "unprognostic (7.06e-3)" 0.1 0.3 1.1 0.0 2.5 0.0 4.3 0.3 2.3 0.0 0.2 0.0 0.0 0.0 607.6 0.0 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.3 0.4 0.1 178.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.5 2.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 8.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.5 0.3 2.3 2.9 0.3 0.3 0.4 0.3 0.3 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 39.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 8.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 CLPSL2 "C6orf126, dJ510O8.5, UNQ3045" ENSG00000196748 "Colipase like 2" Q6UWE3 6 35776594-35779552 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "epididymis: 532.1" "Group enriched" "Detected in some" 4 "Breast glandular cells: 3.4;Breast myoepithelial cells: 2.2;Enteroendocrine cells: 1.8;Exocrine glandular cells: 4.0;Pancreatic endocrine cells: 2.1;Spermatogonia: 2.2" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "T-47d: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA051655 Approved "Secreted in male reproductive system" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 1: Pancreatic cells - Digestion" "HPA051655: " "unprognostic (2.38e-1)" "unprognostic (3.65e-1)" "unprognostic (6.39e-3)" "unprognostic (9.38e-2)" "unprognostic (4.03e-2)" "unprognostic (2.47e-1)" "unprognostic (4.85e-3)" "unprognostic (8.69e-2)" "unprognostic (3.17e-2)" "unprognostic (3.95e-2)" "unprognostic (1.49e-1)" "unprognostic (1.13e-1)" "unprognostic (2.37e-1)" 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.2 0.8 0.0 0.2 0.0 0.0 0.0 532.1 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.4 0.0 5.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.7 0.7 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.2 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.7 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.3 0.0 0.1 6.3 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.4 0.2 0.8 0.6 0.4 0.2 0.4 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 2.2 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 1.8 0.0 0.2 4.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 CLPX ENSG00000166855 "Caseinolytic mitochondrial matrix peptidase chaperone subunit X" O76031 15 65148219-65185342 "Disease related genes, Predicted intracellular proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 242.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040262, HPA048199" Approved Supported Nucleoplasm,Mitochondria,Cytosol "Intracellular and membrane" NA NA 65000 "Cluster 49: Eosinophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "Nucleoplasm, Cytosol" "HPA040262: AB_10793961, HPA048199: AB_2680312" "unprognostic (2.78e-1)" "unprognostic (6.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.69e-2)" "unprognostic (2.00e-2)" "unprognostic (3.06e-1)" "unprognostic (1.18e-3)" "unprognostic (2.64e-1)" "unprognostic (3.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.53e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.93e-9)" "unprognostic (1.76e-1)" "unprognostic (2.64e-1)" "unprognostic (5.95e-2)" "unprognostic (3.50e-2)" 7.9 10.8 9.2 6.1 9.7 8.0 9.3 9.5 11.0 7.6 7.4 9.2 8.8 7.8 8.6 13.3 7.9 6.3 14.1 7.8 8.3 12.2 32.9 6.5 9.1 9.8 8.9 9.4 9.4 11.9 4.6 9.8 8.5 8.0 8.0 10.1 7.6 6.0 26.8 14.7 7.4 7.1 8.8 8.4 9.2 9.1 9.4 10.6 9.8 24.0 9.9 7.9 8.9 10.1 8.1 13.7 11.7 14.8 12.2 15.5 12.5 9.2 10.2 9.8 10.3 13.7 11.1 25.0 7.5 12.3 7.3 16.9 43.2 12.1 10.5 9.9 7.9 18.9 12.8 17.4 17.3 24.4 10.5 18.6 16.2 9.0 17.1 11.3 12.6 13.3 17.6 8.6 11.7 10.3 11.6 21.4 13.1 16.0 6.1 22.4 13.9 26.1 18.6 18.5 10.1 8.1 12.4 19.3 13.8 15.3 8.9 20.3 11.2 9.8 8.7 8.0 8.7 9.2 15.0 13.0 9.6 30.4 7.8 2.2 4.1 6.5 4.3 3.5 3.9 4.4 3.7 3.2 3.9 3.9 5.0 4.0 6.4 4.7 3.3 5.9 3.5 2.7 9.2 9.7 9.5 11.0 7.8 8.3 9.8 8.9 8.5 8.8 9.4 10.1 16.4 35.3 35.5 15.3 23.6 19.2 18.8 20.9 18.8 32.3 17.0 15.6 69.9 27.1 29.5 33.1 14.6 41.0 28.5 16.7 21.5 36.8 104.5 24.4 28.7 21.0 10.3 56.8 15.6 31.6 29.2 25.5 33.6 27.5 16.4 37.8 21.0 90.1 22.6 32.0 15.2 20.3 28.5 28.3 16.6 242.3 28.9 20.3 17.8 16.9 34.1 25.9 20.6 12.5 23.9 29.0 18.2 29.7 30.8 24.9 23.1 33.8 27.7 27.2 26.3 23.1 30.1 45.0 30.6 29.1 30.1 89.2 24.4 59.0 24.3 25.5 CLRN1 "RP61, USH3, USH3A" ENSG00000163646 "Clarin 1" P58418 3 150926163-150972727 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 4.9;retina: 12.8" "Cell type enriched" "Detected in some" 6 "Muller glia cells: 165.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 30 "NTERA-2: 3.3" "Low region specificity" "Detected in some" "Not detected" "Not detected" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (1.00e-3)" "unprognostic (1.26e-1)" "unprognostic (5.54e-1)" "unprognostic (9.68e-2)" 0.0 4.9 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 165.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CLSTN3 "CDHR14, CSTN3, KIAA0726" ENSG00000139182 "Calsyntenin 3" Q9BQT9 12 7129698-7158945 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 161.2;Cone photoreceptor cells: 62.6;Excitatory neurons: 79.4;Inhibitory neurons: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 6.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 1700000 "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "prognostic favorable (5.08e-4)" "unprognostic (2.84e-2)" "unprognostic (1.06e-3)" "unprognostic (1.33e-2)" "unprognostic (6.73e-3)" "unprognostic (6.35e-2)" "unprognostic (9.52e-2)" "unprognostic (2.58e-1)" "unprognostic (2.94e-1)" "unprognostic (1.85e-1)" "prognostic favorable (1.19e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.49e-5)" "unprognostic (2.19e-2)" "unprognostic (6.14e-2)" "unprognostic (1.91e-1)" "prognostic favorable (8.07e-4)" 12.9 14.5 23.1 13.6 20.8 12.4 13.3 18.6 42.7 13.4 0.0 8.3 6.8 11.0 2.7 6.8 11.7 10.1 7.0 21.1 33.9 21.2 29.2 12.7 14.3 13.5 7.7 25.4 10.4 11.2 30.3 3.7 24.8 9.6 3.9 20.2 11.0 4.4 2.5 10.5 14.2 7.3 0.7 20.7 7.5 4.3 22.3 10.2 12.4 1.6 9.0 9.9 9.6 14.0 6.7 11.2 4.3 10.3 4.7 5.2 30.1 3.9 9.4 7.1 12.1 18.3 10.1 12.1 2.9 6.0 9.1 8.4 6.7 8.0 3.5 10.9 7.5 19.2 19.9 18.6 5.9 2.7 34.6 15.2 5.9 8.5 7.4 30.6 9.1 11.2 19.0 6.6 1.3 2.4 8.3 2.8 12.6 0.6 0.7 5.3 0.1 3.5 10.7 13.8 5.6 9.2 8.4 9.5 1.7 10.4 5.4 7.0 4.6 3.9 13.6 8.6 2.4 8.7 2.2 1.6 7.6 3.2 2.8 1.5 0.0 0.0 3.3 0.0 1.9 0.1 1.5 2.9 0.1 0.1 0.5 1.2 0.2 6.9 0.0 0.0 2.0 1.0 23.1 20.8 18.6 42.7 21.1 33.9 13.5 7.7 24.8 0.7 22.3 14.0 6.0 0.0 3.9 5.2 2.8 4.1 2.3 4.9 7.4 161.2 15.7 7.5 2.3 4.3 3.3 14.7 62.6 5.4 14.1 2.9 0.0 9.2 1.2 3.3 18.0 15.3 29.3 1.3 79.4 7.5 9.3 12.0 7.7 6.3 5.7 8.6 5.7 26.6 1.2 26.9 60.2 4.0 16.2 2.0 7.3 1.9 12.8 3.6 5.4 4.7 1.1 9.5 13.4 10.6 3.1 7.2 3.2 6.4 12.7 1.9 1.3 23.3 3.0 40.3 6.6 5.1 6.8 0.7 1.1 2.7 5.7 3.3 16.6 6.8 3.6 1.8 CLU "APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2" ENSG00000120885 Clusterin P10909 8 27596917-27614700 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Complement pathway, Immunity, Innate immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 10230.8;liver: 9779.1" "Group enriched" "Detected in all" 4 "Cholangiocytes: 2586.5;Collecting duct cells: 3525.7;Hepatocytes: 4230.2;Muller glia cells: 8522.6" "Cancer enhanced" "Detected in all" "glioma: 1485.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 767.1" "Lineage enriched" "Detected in all" 33 "granulocytes: 767.1" "Cell line enhanced" "Detected in all" "HeLa: 3644.3;SK-BR-3: 3500.4;T-47d: 2562.4;U-2 OS: 2225.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000572, CAB016253, HPA075983" Enhanced Supported Cytosol "Secreted to blood" NA NA 169000000000 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Cytosol "CAB016253: AB_673562, HPA000572: AB_1078539, HPA075983: " "unprognostic (1.10e-2)" "unprognostic (1.81e-2)" "unprognostic (1.14e-3)" "unprognostic (2.74e-2)" "unprognostic (5.59e-2)" "unprognostic (4.13e-2)" "unprognostic (1.76e-2)" "unprognostic (2.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.66e-5)" "unprognostic (5.29e-2)" 1438.7 3809.7 6730.2 897.0 6536.5 53.2 1423.8 6992.3 8050.5 1389.4 6057.7 1407.9 323.9 1152.5 9148.8 768.6 3543.7 2863.5 617.7 6660.5 8149.9 1170.5 9779.1 827.8 2309.4 10230.8 8450.9 756.7 2246.3 1689.2 827.2 131.2 8001.8 986.4 276.1 3274.6 1453.0 5466.4 114.1 281.9 662.7 1439.9 8813.6 295.4 1081.6 2709.4 7385.0 388.1 2406.8 267.7 2343.1 1777.4 741.0 9752.3 13.0 1673.1 73.2 86.4 401.4 546.1 230.7 297.8 584.8 77.3 40.1 323.4 265.5 6.6 1159.9 267.1 926.6 561.2 318.4 48.1 50.3 1268.7 306.4 741.8 3644.3 403.7 348.8 19.2 1891.2 923.4 189.1 334.0 95.5 719.5 1028.1 10.6 10.1 842.2 27.5 288.4 5.7 56.5 603.3 505.3 197.6 6.5 276.1 236.3 763.0 1220.2 66.7 41.7 412.3 3500.4 18.1 349.1 2562.4 10.3 153.2 24.0 2225.3 131.8 101.9 108.1 419.0 16.1 1808.8 122.4 10.3 767.1 18.4 8.9 19.8 6.2 7.4 0.7 23.1 21.3 6.2 1.6 2.8 7.0 79.8 9.3 1.1 11.8 6.5 1073.6 6730.2 6536.5 6992.3 8050.5 6660.5 8149.9 10230.8 8450.9 8001.8 8813.6 7385.0 9752.3 255.3 32.1 91.8 720.5 16.1 81.3 944.6 134.1 118.9 74.3 475.3 480.4 86.1 2586.5 514.0 3525.7 77.2 116.3 15.2 23.6 41.1 488.3 311.3 196.9 31.1 442.0 9.5 92.4 73.4 620.7 22.7 614.8 226.8 185.6 803.0 31.4 1037.7 4230.2 12.6 30.3 81.0 30.9 28.5 180.5 88.9 789.3 114.3 244.6 206.3 69.3 25.1 8522.6 11.3 61.3 54.3 174.8 15.0 57.2 11.6 200.5 9.9 459.2 709.1 221.4 13.1 334.4 157.7 189.8 20.3 58.8 55.3 85.6 58.7 288.9 49.3 353.7 CLUL1 ENSG00000079101 "Clusterin like 1" Q15846 18 596988-650334 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 31 "retina: 297.9" "Cell type enriched" "Detected in many" 7 "Rod photoreceptor cells: 407.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 34.3" "Not detected" "Not detected" "CAB025264, HPA075240" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted in other tissues" NA NA 11000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 79: Retina - Phototransduction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "Plasma membrane" "CAB025264: , HPA075240: AB_2732286" "unprognostic (1.75e-2)" "unprognostic (9.15e-2)" "unprognostic (1.50e-1)" "unprognostic (1.51e-1)" "unprognostic (7.81e-3)" "unprognostic (3.00e-3)" "unprognostic (1.96e-1)" "unprognostic (2.97e-3)" "unprognostic (8.38e-3)" "unprognostic (3.76e-2)" "unprognostic (4.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.36e-4)" "unprognostic (1.32e-1)" "unprognostic (7.89e-2)" "unprognostic (1.29e-3)" "unprognostic (2.37e-2)" 0.4 1.0 2.7 0.5 6.1 3.9 2.3 2.0 4.0 1.5 7.2 0.9 0.5 1.4 0.5 1.2 1.8 2.0 0.3 3.1 4.2 5.3 0.5 1.4 0.7 3.0 3.4 4.9 1.3 3.6 3.9 0.6 3.1 8.5 0.1 297.9 2.3 1.1 0.2 0.7 1.4 0.1 3.1 0.1 3.1 2.6 4.3 1.7 6.8 0.0 0.0 0.8 0.1 9.5 3.6 5.4 10.1 6.8 0.0 0.0 6.1 3.9 0.3 0.0 0.0 4.2 2.1 4.3 1.0 0.0 3.6 1.5 0.0 0.6 0.0 3.6 9.3 7.3 2.9 34.3 0.0 2.5 1.3 0.3 0.0 0.0 0.0 1.7 0.4 10.5 10.5 12.3 0.0 1.2 4.4 7.8 0.7 4.4 2.4 8.8 4.8 15.5 1.1 1.1 8.8 6.2 4.0 2.5 3.4 8.0 3.3 1.0 0.8 4.0 5.7 2.8 2.0 6.9 13.3 9.7 3.2 4.7 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.3 0.0 2.7 6.1 2.0 4.0 3.1 4.2 3.0 3.4 3.1 3.1 4.3 9.5 0.1 0.0 2.6 0.3 0.1 0.0 3.8 1.5 2.8 29.6 2.8 5.0 0.2 0.0 1.7 0.0 20.9 0.8 0.0 0.1 1.9 0.4 0.7 2.5 0.3 2.0 0.0 0.0 5.2 0.2 0.1 0.4 0.0 3.2 0.0 3.5 0.0 0.0 0.2 16.8 3.8 0.0 0.0 0.0 0.3 0.8 0.9 0.2 0.0 1.0 0.0 58.1 0.0 0.0 4.9 0.0 0.0 1.2 0.0 5.5 0.0 0.5 2.4 407.5 6.6 0.0 0.3 10.6 8.6 0.2 0.1 0.4 0.1 17.3 0.1 1.6 CMA1 ENSG00000092009 "Chymase 1" P23946 14 24505353-24508265 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 18.5" "Cell type enriched" "Detected in some" 28 "granulocytes: 53.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000363, HPA052634" Enhanced Supported "Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 3000000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 60: Granulocytes - Receptor signaling" "Cytoplasmic bodies" Cytosol "CAB000363: AB_2083616, HPA052634: AB_2681892" "unprognostic (1.37e-1)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" "unprognostic (7.07e-3)" "unprognostic (1.48e-2)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.21e-1)" "unprognostic (8.91e-3)" "unprognostic (4.19e-3)" "unprognostic (1.29e-4)" "unprognostic (2.52e-3)" "unprognostic (7.78e-2)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" 9.0 0.0 0.2 3.7 0.1 0.2 18.5 0.0 0.2 4.6 0.3 8.7 0.6 3.1 4.3 10.2 0.9 7.3 1.6 0.1 0.2 0.2 0.5 1.5 1.8 0.5 0.3 0.1 1.6 0.6 0.2 0.1 0.3 1.0 8.3 0.0 4.7 1.3 0.9 9.0 5.8 2.2 0.3 0.2 1.5 0.9 0.2 3.0 0.4 3.0 2.4 11.1 0.9 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.2 0.1 0.2 0.5 0.3 0.3 0.3 0.2 0.2 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 53.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 CMPK1 "CMPK, UMP-CMPK" ENSG00000162368 "Cytidine/uridine monophosphate kinase 1" P30085 1 47333797-47378839 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053730, HPA058604" Approved Supported Nucleoplasm "Intracellular and membrane" NA NA 1400000 "Cluster 34: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm "HPA053730: AB_2682244, HPA058604: AB_2683773" "unprognostic (2.16e-2)" "unprognostic (1.16e-1)" "unprognostic (9.39e-3)" "unprognostic (1.18e-1)" "unprognostic (1.09e-3)" "unprognostic (1.50e-2)" "unprognostic (1.59e-2)" "unprognostic (9.88e-2)" "unprognostic (5.80e-2)" "unprognostic (2.90e-2)" "unprognostic (1.71e-2)" "unprognostic (2.61e-1)" "unprognostic (1.28e-2)" "unprognostic (2.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-3)" "unprognostic (7.36e-2)" 88.2 45.2 47.0 64.2 50.6 53.1 102.2 51.9 73.1 74.8 49.8 134.1 163.9 44.2 42.2 108.2 35.2 88.5 63.3 44.5 56.9 78.7 217.2 63.8 71.8 52.6 52.4 38.1 90.9 57.7 32.9 48.8 54.2 95.0 141.0 29.2 157.4 50.7 71.1 65.1 152.5 56.0 52.6 58.0 109.0 17.5 52.3 61.7 92.0 73.9 87.9 80.6 63.8 55.3 124.9 68.4 86.6 77.9 154.6 179.3 122.5 216.4 129.8 128.6 129.9 61.3 84.1 183.4 108.6 147.9 120.5 82.7 64.8 112.1 174.9 279.5 52.7 142.9 91.0 106.7 100.8 206.2 100.2 101.2 132.7 107.5 119.7 121.1 135.2 67.4 137.3 143.5 169.8 45.9 168.2 96.8 55.1 162.9 93.6 103.4 149.8 138.5 126.5 134.9 78.3 41.3 155.0 177.7 128.9 113.7 44.2 121.0 127.7 159.6 92.7 154.5 180.8 103.8 154.3 124.4 126.3 125.3 111.7 43.3 12.8 24.2 16.1 14.0 20.7 13.6 18.0 20.0 13.5 14.3 16.9 16.4 5.3 19.4 17.0 11.4 20.9 15.6 47.0 50.6 51.9 73.1 44.5 56.9 52.6 52.4 54.2 52.6 52.3 55.3 101.7 70.5 54.4 14.4 148.1 175.5 125.3 88.9 102.4 34.2 167.8 67.7 48.9 147.3 87.0 75.4 16.7 82.3 117.9 280.0 174.1 186.8 1.6 56.2 63.3 83.8 117.5 126.0 28.5 181.6 133.0 91.2 125.4 98.2 94.0 39.7 88.5 235.9 75.9 43.7 30.2 326.6 91.6 122.0 265.0 5.0 59.4 107.1 254.3 31.9 100.5 66.9 124.6 20.6 25.0 146.8 168.6 70.0 119.8 203.5 234.6 254.5 112.3 31.1 85.5 75.9 95.8 14.0 29.8 167.0 195.1 118.3 160.5 49.0 240.2 250.8 CNBD1 FLJ35802 ENSG00000176571 "Cyclic nucleotide binding domain containing 1" Q8NA66 8 86866415-87615219 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 6.6" "Group enriched" "Detected in some" 33 "Early spermatids: 155.4;Late spermatids: 92.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Karpas-707: 4.4;U-266/70: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025037, HPA027469, HPA027786" Uncertain "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA025037: AB_10794318, HPA027469: AB_10599492, HPA027786: AB_10600231" "unprognostic (1.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 155.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 92.3 1.2 0.0 0.0 1.0 0.0 0.0 0.0 2.0 2.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CNDP1 "CN1, CPGL2, HsT2308, MGC10825" ENSG00000150656 "Carnosine dipeptidase 1" Q96KN2 18 74534500-74587212 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 85.6" "Cell type enriched" "Detected in some" 10 "Oligodendrocytes: 361.7" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 38 "U-266/84: 15.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008933, HPA073283" Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 70: Brain - Nervous system development" "Cluster 16: U-266 - Nucleosome" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008933: AB_1847033, HPA073283: " "unprognostic (7.43e-3)" "unprognostic (6.00e-2)" "unprognostic (8.55e-3)" "unprognostic (3.93e-1)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (8.04e-3)" "unprognostic (1.12e-2)" "unprognostic (2.81e-1)" "unprognostic (1.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "unprognostic (6.90e-3)" "unprognostic (1.14e-1)" "unprognostic (3.30e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" 0.0 0.0 27.4 0.0 74.2 0.1 0.0 80.4 39.0 0.0 6.0 0.0 1.3 0.0 0.7 0.0 0.0 0.1 0.0 30.5 51.3 0.5 12.9 0.0 0.0 85.6 76.9 0.0 0.0 0.0 0.2 0.0 74.3 0.1 0.0 0.1 0.0 0.1 1.4 0.1 0.2 0.0 39.7 0.0 0.0 0.3 74.9 0.0 0.2 0.0 0.0 0.0 0.0 80.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 15.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 27.4 74.2 80.4 39.0 30.5 51.3 85.6 76.9 74.3 39.7 74.9 80.7 0.2 0.0 0.0 0.3 0.2 0.1 0.4 0.2 0.0 0.6 0.5 0.3 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 8.6 0.5 0.2 0.2 0.0 2.7 1.2 0.2 0.0 0.3 0.0 1.5 0.0 0.2 0.7 35.1 0.1 0.0 1.5 0.7 0.0 1.2 1.1 3.1 0.0 0.2 0.0 1.0 0.0 0.5 0.0 3.0 361.7 0.2 0.1 0.0 0.0 0.4 0.4 24.5 0.0 1.0 0.0 0.6 0.2 1.0 0.4 0.0 0.3 0.0 0.4 0.0 0.5 0.2 CNOT1 "AD-005, CDC39, KIAA1007, NOT1, NOT1H" ENSG00000125107 "CCR4-NOT transcription complex subunit 1" A5YKK6 16 58519951-58629885 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Autism spectrum disorder, Disease variant, Holoprosencephaly, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046577, HPA049664" Approved Supported Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA046577: AB_2679706, HPA049664: AB_2680844" "unprognostic (1.30e-2)" "unprognostic (6.86e-2)" "unprognostic (9.25e-3)" "unprognostic (1.66e-1)" "unprognostic (2.39e-2)" "unprognostic (7.11e-2)" "unprognostic (3.58e-2)" "unprognostic (2.19e-1)" "unprognostic (6.43e-2)" "unprognostic (6.99e-2)" "unprognostic (1.83e-2)" "unprognostic (6.63e-2)" "unprognostic (1.33e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (5.53e-2)" "unprognostic (1.52e-1)" 29.8 35.2 8.4 46.9 10.7 45.6 36.3 17.4 11.5 34.7 33.5 60.1 55.0 31.8 27.6 73.1 38.9 28.3 26.3 8.6 9.4 39.8 36.0 33.3 58.1 11.5 10.5 39.2 41.1 59.7 21.2 35.1 11.3 31.2 57.3 32.4 38.8 30.6 52.4 43.1 52.3 33.7 8.9 42.9 42.1 108.2 10.6 76.4 42.4 44.1 69.5 49.1 38.6 15.2 128.8 148.2 110.0 88.1 52.1 66.2 127.6 99.6 85.8 111.4 82.0 167.6 75.3 194.0 47.4 75.8 65.5 122.3 177.9 101.0 149.2 72.5 98.8 150.4 121.8 193.7 70.8 235.8 162.4 64.0 67.5 129.7 151.5 66.9 87.7 107.2 181.0 55.3 76.4 52.0 182.6 61.2 114.4 84.9 127.2 229.0 189.5 122.7 62.4 180.0 90.9 58.6 336.0 113.5 56.0 100.5 67.9 121.3 100.9 81.3 80.0 62.2 88.7 124.7 138.2 390.3 85.5 99.4 76.9 18.3 12.1 13.4 13.8 15.6 18.2 14.7 12.9 14.0 14.6 13.8 12.1 12.6 18.6 15.4 22.5 7.3 15.4 11.5 8.4 10.7 17.4 11.5 8.6 9.4 11.5 10.5 11.3 8.9 10.6 15.2 44.4 16.0 42.9 33.0 57.8 47.4 32.6 42.9 25.6 28.2 33.9 27.9 23.8 37.1 45.2 23.9 29.2 33.7 86.3 64.5 9.8 29.8 107.7 57.6 48.0 31.3 36.1 45.0 31.7 47.0 29.9 30.7 35.2 78.2 32.2 45.9 23.9 42.3 35.7 40.4 35.6 54.2 24.4 51.5 39.5 38.6 24.8 46.4 19.6 42.2 50.0 20.0 34.0 42.3 54.9 42.5 34.9 32.4 59.8 43.6 60.1 22.9 51.6 24.3 32.9 38.7 30.4 136.6 64.3 56.0 47.0 37.9 52.1 27.9 64.5 61.2 CNOT9 "CAF40, CT129, RCD1, RCD1+, RQCD1" ENSG00000144580 "CCR4-NOT transcription complex subunit 9" Q92600 2 218568580-218597080 "Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046622 Approved Approved "Cytoplasmic bodies" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Cytoplasmic bodies" "HPA046622: AB_10962694" "unprognostic (7.70e-2)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.58e-2)" "unprognostic (1.34e-1)" "unprognostic (1.30e-2)" "prognostic unfavorable (8.41e-9)" "unprognostic (8.08e-3)" "unprognostic (1.91e-3)" "unprognostic (1.53e-2)" "unprognostic (7.02e-2)" "unprognostic (6.89e-2)" "prognostic unfavorable (4.69e-9)" "unprognostic (1.87e-2)" "unprognostic (2.38e-2)" "unprognostic (2.05e-1)" "unprognostic (4.67e-2)" 17.2 21.9 18.3 26.0 19.7 40.2 16.6 20.8 19.4 17.8 18.9 17.7 18.1 17.6 19.4 21.4 18.8 16.1 20.1 18.7 19.4 16.3 21.0 18.2 31.3 18.6 19.2 18.7 15.8 21.0 25.2 18.0 18.6 18.4 22.6 26.1 15.1 15.0 22.4 20.5 17.3 20.2 19.4 22.6 17.1 27.0 18.9 33.6 15.4 17.1 36.2 21.8 17.6 22.1 49.9 38.2 62.2 82.2 35.2 33.8 79.8 55.5 57.4 69.6 67.4 68.2 40.4 55.4 33.7 64.3 60.9 57.2 88.1 61.6 81.4 79.8 55.6 110.6 72.1 81.1 48.9 120.2 61.7 31.0 48.5 73.1 74.2 32.7 53.1 74.0 67.1 121.1 56.3 40.0 117.2 72.8 94.5 38.4 60.4 97.8 88.7 57.1 37.1 71.5 79.2 64.8 54.5 47.5 52.2 59.1 38.1 66.5 43.2 75.5 55.8 55.3 69.0 57.6 62.6 128.3 53.7 73.1 55.0 36.9 25.6 29.1 41.5 31.7 36.4 29.9 34.0 35.4 30.4 26.6 31.8 35.0 10.5 35.5 34.0 35.1 30.8 37.9 18.3 19.7 20.8 19.4 18.7 19.4 18.6 19.2 18.6 19.4 18.9 22.1 22.1 22.4 20.7 0.0 10.0 0.0 0.0 0.0 0.0 0.0 20.4 15.1 0.0 0.0 9.9 12.9 0.0 28.4 27.1 0.0 27.4 21.2 0.0 32.2 21.2 10.3 0.0 0.0 0.0 20.7 40.7 10.9 0.0 22.4 16.4 18.9 0.0 0.0 28.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 20.7 0.0 0.0 0.0 0.0 25.6 0.0 0.0 7.0 0.0 0.0 16.1 10.2 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 28.3 11.0 16.9 0.0 0.0 CNPY2 "HP10390, TMEM4, ZSIG9" ENSG00000257727 "Canopy FGF signaling regulator 2" Q9Y2B0 12 56309842-56316119 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 475.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038465, HPA038466" Supported Supported Cytosol "Intracellular and membrane" NA NA 220000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA038465: AB_10967609, HPA038466: AB_10672646" "unprognostic (3.83e-2)" "unprognostic (5.62e-2)" "unprognostic (2.49e-1)" "unprognostic (2.46e-2)" "unprognostic (4.33e-2)" "unprognostic (2.20e-1)" "unprognostic (1.17e-3)" "unprognostic (1.46e-1)" "unprognostic (7.68e-2)" "unprognostic (2.04e-3)" "prognostic favorable (8.37e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (2.32e-8)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "unprognostic (2.67e-2)" "unprognostic (5.06e-2)" 36.7 52.5 28.4 25.8 30.3 24.7 41.8 30.0 30.7 43.3 38.1 36.6 30.9 35.6 74.4 34.1 38.1 25.4 28.4 27.7 31.8 37.8 75.7 30.5 22.0 31.1 29.0 42.7 58.9 47.3 66.8 40.8 28.9 35.3 38.5 18.8 53.1 36.4 21.2 23.5 34.6 24.9 30.5 35.1 42.1 20.0 29.8 27.0 44.7 18.6 26.6 32.9 31.1 32.2 50.6 75.5 76.0 62.8 186.0 64.0 120.7 51.0 117.4 108.7 76.5 116.0 87.9 51.2 95.0 132.4 53.2 72.4 92.3 62.8 68.7 51.3 57.5 49.9 106.1 121.8 83.6 94.9 60.4 76.5 80.5 89.9 106.6 165.5 91.1 59.0 73.8 113.5 81.3 76.2 58.2 105.3 72.6 107.5 109.5 65.1 58.3 84.9 90.1 47.6 67.9 41.7 85.1 86.8 93.6 92.7 78.0 176.8 41.2 42.7 33.6 52.2 74.7 58.4 88.2 41.5 90.2 88.2 70.9 56.8 66.5 36.8 65.8 56.9 77.8 73.2 70.7 71.7 69.5 66.2 70.4 67.0 9.8 70.9 34.6 71.3 68.4 76.4 28.4 30.3 30.0 30.7 27.7 31.8 31.1 29.0 28.9 30.5 29.8 32.2 76.2 48.1 93.7 17.3 79.2 54.8 75.2 129.9 17.1 80.5 178.6 191.6 9.8 140.2 95.2 101.2 64.6 248.3 74.0 80.2 52.8 191.8 40.2 54.7 59.9 72.6 141.9 34.3 31.8 168.7 475.0 77.5 31.1 53.1 91.3 60.7 98.9 185.8 147.4 58.9 32.4 187.2 103.7 59.2 55.8 17.7 103.8 47.8 122.7 13.1 99.7 88.6 125.7 40.2 45.6 162.4 114.1 100.1 68.2 107.4 176.6 145.5 74.1 92.2 26.3 59.1 82.8 72.4 44.0 20.0 53.8 236.4 60.5 78.2 177.8 71.0 CNPY3 "CAG4A, TNRC5" ENSG00000137161 "Canopy FGF signaling regulator 3" Q9BT09 6 42929192-42939294 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" Chaperone "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 248.5;Kupffer cells: 233.3;monocytes: 207.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016560 Uncertain "Intracellular and membrane" NA NA 4100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 57: B-cells - Immune response" "HPA016560: AB_1858173" "unprognostic (5.26e-3)" "unprognostic (6.63e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (8.15e-2)" "unprognostic (3.12e-1)" "unprognostic (1.79e-1)" "unprognostic (5.70e-3)" "unprognostic (5.11e-2)" "unprognostic (4.77e-2)" "unprognostic (1.94e-2)" "unprognostic (2.26e-3)" "unprognostic (4.54e-2)" "prognostic unfavorable (9.85e-6)" "unprognostic (2.34e-1)" "unprognostic (1.93e-2)" "unprognostic (2.21e-2)" "unprognostic (2.98e-3)" 35.3 31.4 58.2 64.3 59.1 144.6 32.7 59.0 72.8 40.0 70.0 30.9 30.9 37.5 32.3 23.4 49.8 37.8 28.8 59.7 64.2 31.8 64.7 45.4 78.6 70.0 63.1 48.5 90.0 29.0 41.7 47.6 67.0 45.1 29.7 23.9 32.5 33.8 10.9 22.2 50.1 42.0 62.8 105.2 36.7 46.7 65.8 115.8 34.1 16.7 69.2 43.3 30.0 75.8 78.2 75.6 72.8 157.0 118.4 44.8 73.5 60.3 78.9 79.1 91.0 85.2 57.0 82.1 91.0 102.9 170.8 63.7 54.7 68.7 48.2 82.7 61.6 88.6 65.2 134.0 70.0 155.7 173.3 54.3 41.7 61.2 67.4 113.9 72.4 77.6 73.3 157.3 51.9 147.9 141.4 188.8 59.1 367.3 42.1 97.2 50.6 123.2 79.6 58.6 78.5 68.9 37.7 38.6 134.4 93.4 49.8 334.6 54.6 82.7 82.9 30.9 66.0 107.0 78.9 115.0 34.2 178.6 70.9 212.7 483.3 249.0 115.2 336.3 110.9 267.3 101.1 126.1 407.0 258.7 112.6 115.1 852.8 132.3 327.2 696.4 102.2 404.5 58.2 59.1 59.0 72.8 59.7 64.2 70.0 63.1 67.0 62.8 65.8 75.8 32.3 12.8 11.1 4.2 132.1 22.8 32.1 41.1 31.9 41.6 25.6 29.7 16.9 22.8 26.2 23.9 14.6 51.1 176.5 16.7 7.9 47.4 61.0 25.9 24.2 36.7 55.3 47.9 5.1 34.1 180.8 33.9 20.9 31.8 46.3 81.5 42.1 58.9 248.5 1.7 6.7 31.1 34.6 233.3 61.7 81.7 33.5 184.3 30.2 18.7 207.0 20.8 62.8 4.5 6.6 27.9 34.9 30.1 70.7 50.8 38.4 18.1 32.8 11.1 19.7 12.6 28.0 72.3 39.9 23.9 17.0 36.1 64.1 39.8 36.5 37.9 CNPY4 "MGC40499, PRAT4B" ENSG00000166997 "Canopy FGF signaling regulator 4" Q8N129 7 100119634-100125508 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Leydig cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014166, HPA025240" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA014166: AB_1853895, HPA025240: AB_2082630" "unprognostic (9.64e-2)" "unprognostic (1.59e-2)" "unprognostic (4.09e-3)" "unprognostic (8.44e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.71e-1)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (6.16e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (6.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (1.35e-2)" 13.7 16.8 13.3 9.6 13.9 6.1 11.0 14.3 14.9 24.6 14.7 14.1 6.4 21.2 14.8 5.7 15.4 16.7 13.1 13.1 13.7 10.4 6.6 9.2 10.8 14.2 13.8 24.5 4.5 12.8 16.6 21.3 14.1 10.8 9.9 17.2 5.7 15.9 5.1 8.3 9.7 21.4 13.8 13.6 7.8 6.8 13.6 14.3 10.4 7.1 9.8 12.4 14.8 14.3 7.9 13.5 33.2 59.6 76.0 36.5 16.6 29.0 31.2 14.9 27.8 7.5 7.0 17.2 32.9 52.5 10.9 7.9 13.0 14.2 15.6 16.2 13.4 7.1 23.3 10.4 21.5 12.1 12.8 33.4 3.8 13.7 6.2 32.7 52.4 8.2 6.0 11.1 21.5 22.9 25.8 15.9 17.1 5.0 19.2 7.5 24.9 9.2 15.4 2.0 8.3 16.9 27.8 22.4 15.4 21.4 11.3 6.7 42.9 47.5 28.5 20.2 13.3 9.4 16.3 15.3 27.8 18.4 19.7 11.8 5.1 8.6 15.1 11.2 19.8 3.9 15.6 19.0 7.2 2.9 12.7 19.0 2.3 12.3 13.9 4.6 13.8 6.7 13.3 13.9 14.3 14.9 13.1 13.7 14.2 13.8 14.1 13.8 13.6 14.3 15.2 6.4 2.6 4.2 3.4 3.6 2.3 7.9 2.8 6.9 3.4 6.2 3.4 5.7 4.0 12.9 2.1 35.3 5.2 3.7 1.9 6.4 0.5 5.1 20.2 15.0 2.4 11.8 3.4 2.5 10.3 28.4 1.1 4.2 9.5 16.1 18.2 1.3 14.0 8.4 4.0 1.9 4.1 2.5 2.4 2.2 35.1 4.7 16.0 2.8 5.1 26.6 8.2 2.0 2.8 2.4 2.8 31.6 1.9 0.5 2.8 3.3 4.4 15.8 13.1 12.7 15.5 1.1 4.5 2.1 3.8 18.3 8.6 30.5 2.3 1.0 CNTFR ENSG00000122756 "Ciliary neurotrophic factor receptor" P26992 9 34551432-34590140 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 94.1;skeletal muscle: 129.7" "Cell type enhanced" "Detected in many" "Astrocytes: 57.1;Fibroblasts: 22.4;Muller glia cells: 83.6;Paneth cells: 30.6" "Cancer enhanced" "Detected in many" "glioma: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 109.3;SH-SY5Y: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025310 Approved NA NA 55000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "CAB025310: " "unprognostic (1.39e-1)" "unprognostic (9.40e-2)" "unprognostic (1.93e-2)" "unprognostic (1.90e-2)" "unprognostic (2.59e-1)" "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.94e-2)" "unprognostic (1.28e-1)" "unprognostic (9.70e-2)" "unprognostic (4.45e-3)" "unprognostic (1.72e-2)" "unprognostic (6.32e-2)" "unprognostic (4.99e-3)" "unprognostic (7.37e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" 60.0 10.3 67.2 1.3 91.9 0.0 49.7 81.5 69.0 29.7 16.3 7.6 3.3 2.8 2.6 3.9 13.0 6.3 39.0 54.3 58.5 2.9 12.4 3.8 1.0 57.0 82.8 5.2 2.2 0.2 9.7 5.2 62.2 11.0 2.2 13.9 11.3 7.7 129.7 11.5 8.7 0.7 49.8 30.6 7.0 7.2 94.1 5.1 13.7 35.1 0.4 5.6 17.1 47.4 0.0 0.0 109.3 0.0 13.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 3.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.2 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 52.1 0.1 0.1 0.0 1.0 0.4 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 67.2 91.9 81.5 69.0 54.3 58.5 57.0 82.8 62.2 49.8 94.1 47.4 0.9 0.0 0.0 57.1 0.0 3.6 1.1 0.0 1.2 19.3 11.9 1.5 1.3 8.6 0.0 0.0 6.2 0.9 0.1 6.5 1.9 0.1 4.3 0.1 2.4 0.3 0.0 0.0 4.1 0.0 0.6 22.4 0.0 0.1 0.0 0.0 2.5 1.4 1.4 3.3 9.3 0.5 0.0 0.0 2.7 1.9 9.9 0.1 3.6 2.8 0.0 83.6 0.0 15.1 0.5 0.0 30.6 2.2 0.3 0.2 14.1 0.1 0.0 3.2 0.0 1.2 1.9 5.5 19.8 0.3 2.4 2.3 0.2 0.0 0.5 0.3 CNTN1 "F3, GP135" ENSG00000018236 "Contactin 1" Q12860 12 40692439-41072415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 158.2" "Group enriched" "Detected in many" 5 "Astrocytes: 763.9;Excitatory neurons: 844.8;Inhibitory neurons: 699.0;Oligodendrocyte precursor cells: 1021.4" "Cancer enhanced" "Detected in many" "glioma: 17.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A549: 224.4;HaCaT: 40.3;SCLC-21H: 68.5;SH-SY5Y: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025200, HPA070467" Enhanced Approved "Intracellular and membrane" NA NA 450000000 "Cluster 17: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB025200: , HPA070467: AB_2732156" "unprognostic (3.18e-2)" "unprognostic (5.96e-3)" "unprognostic (3.66e-2)" "unprognostic (7.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (9.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.32e-2)" "unprognostic (8.15e-4)" "unprognostic (6.98e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (3.75e-4)" 3.9 33.2 64.0 2.5 75.3 0.2 8.8 119.4 84.2 14.1 0.0 3.1 1.7 11.5 2.6 9.1 2.2 11.7 0.8 93.6 59.8 12.4 1.2 4.4 4.5 72.6 94.7 49.2 6.0 1.4 10.4 0.3 70.0 27.8 3.8 26.8 5.4 27.7 0.8 12.8 3.0 10.6 129.0 8.2 5.0 9.4 79.2 1.0 1.2 1.6 3.9 21.5 6.6 158.2 0.1 224.4 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.3 0.3 0.1 0.1 0.0 0.0 40.3 6.0 11.2 0.0 0.2 2.4 0.0 0.7 0.0 0.0 0.0 0.7 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.2 1.5 0.2 0.1 0.0 1.0 0.3 0.0 0.0 68.5 40.3 0.1 2.5 2.7 1.0 0.1 0.6 0.0 0.1 4.3 0.1 10.0 2.8 0.1 0.0 0.3 0.0 0.9 2.6 0.5 0.7 0.3 0.2 0.3 0.4 0.2 0.2 0.1 0.4 0.4 0.2 1.2 0.7 0.4 0.9 0.2 0.0 64.0 75.3 119.4 84.2 93.6 59.8 72.6 94.7 70.0 129.0 79.2 158.2 0.3 0.0 5.9 763.9 0.1 5.2 1.1 1.6 4.0 32.1 0.4 1.8 0.7 0.0 4.5 5.5 29.2 0.0 0.0 0.0 1.9 0.0 34.9 4.3 7.1 0.7 0.0 0.0 844.8 0.0 0.0 13.3 0.0 0.3 0.0 5.0 0.0 0.0 0.1 11.8 699.0 0.0 2.0 0.0 4.0 149.5 62.7 0.1 10.6 54.4 0.0 34.6 0.0 1021.4 23.9 0.7 0.0 60.2 0.0 0.3 0.0 0.0 0.4 5.9 0.0 0.5 3.6 0.6 0.8 2.1 13.5 0.0 0.5 0.3 0.0 0.2 CNTN2 "AXT, TAG-1, TAX, TAX1" ENSG00000184144 "Contactin 2" Q02246 1 205042937-205078289 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cell adhesion" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 248.9" "Cell type enriched" "Detected in some" 11 "Oligodendrocytes: 335.5" "Cancer enriched" "Detected in some" 9 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "NTERA-2: 3.9;SCLC-21H: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001397, HPA012497" Approved "Secreted in brain" NA NA 58000 "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA001397: AB_1847146, HPA012497: AB_1847147" "unprognostic (1.90e-1)" "unprognostic (1.86e-1)" "unprognostic (2.87e-2)" "unprognostic (4.52e-3)" "unprognostic (2.98e-2)" "unprognostic (5.96e-2)" "unprognostic (3.25e-1)" "unprognostic (1.43e-2)" "unprognostic (8.56e-2)" "unprognostic (2.40e-1)" "unprognostic (3.44e-3)" "unprognostic (5.62e-2)" "unprognostic (1.73e-7)" "unprognostic (9.82e-3)" "unprognostic (1.19e-1)" "unprognostic (3.35e-2)" "unprognostic (3.07e-2)" 0.3 0.5 82.6 0.4 145.4 0.0 0.1 125.7 112.4 0.6 32.4 2.1 0.1 0.0 0.0 0.2 0.1 0.1 0.7 85.2 96.6 0.1 0.0 0.0 0.0 161.6 128.1 0.0 0.1 0.0 8.0 0.0 139.8 0.3 0.5 1.2 0.4 0.6 0.0 0.5 0.9 0.2 110.1 0.1 0.5 6.1 125.7 0.1 0.1 0.0 0.3 0.2 0.7 248.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 82.6 145.4 125.7 112.4 85.2 96.6 161.6 128.1 139.8 110.1 125.7 248.9 0.4 0.0 0.6 1.3 0.1 0.0 0.0 0.0 0.0 2.4 0.9 1.3 3.7 0.0 0.6 1.8 0.0 0.0 1.2 0.0 0.0 0.6 13.7 0.6 0.5 0.5 0.0 0.0 18.4 0.6 0.0 0.4 0.0 1.2 0.0 2.6 0.0 0.0 0.0 3.3 16.0 0.0 0.0 0.0 0.0 29.0 0.6 0.5 0.0 4.7 0.0 0.2 0.0 9.5 335.5 0.6 0.0 0.0 0.4 0.0 0.0 0.3 1.5 0.8 0.0 0.0 0.3 3.2 0.6 0.0 0.0 0.0 0.5 0.2 0.0 0.2 CNTN3 "BIG-1, PANG" ENSG00000113805 "Contactin 3" Q9P232 3 74262568-74521140 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.1" "Group enriched" "Detected in many" 7 "Excitatory neurons: 274.0;Inhibitory neurons: 195.1;Oligodendrocyte precursor cells: 228.7" "Cancer enhanced" "Detected in many" "prostate cancer: 2.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BJ: 7.1;fHDF/TERT166: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003341 Approved "Intracellular and membrane" NA NA 130000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA003341: AB_1078556" "unprognostic (1.66e-2)" "unprognostic (1.86e-1)" "unprognostic (2.35e-3)" "unprognostic (9.86e-2)" "unprognostic (1.82e-2)" "unprognostic (1.94e-5)" "unprognostic (4.25e-2)" "unprognostic (2.13e-3)" "unprognostic (8.42e-2)" "unprognostic (3.85e-2)" "unprognostic (1.50e-1)" "unprognostic (7.25e-2)" "unprognostic (9.30e-7)" "unprognostic (4.23e-2)" "unprognostic (1.63e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-2)" 2.7 3.0 5.0 0.4 6.4 0.0 1.4 0.0 10.1 2.4 0.7 3.2 0.4 0.9 1.7 0.4 7.6 2.0 2.1 6.2 0.7 3.7 3.1 0.8 0.1 1.3 3.0 1.3 2.0 0.2 4.0 0.1 1.9 5.8 2.8 1.3 0.8 4.2 0.2 0.8 0.5 0.4 0.0 1.8 1.4 0.7 1.3 0.9 1.6 0.2 0.5 4.3 0.5 1.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 7.1 0.0 1.1 0.3 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 2.4 0.0 1.4 0.0 0.1 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 6.4 0.0 10.1 6.2 0.7 1.3 3.0 1.9 0.0 1.3 1.0 0.2 3.2 1.7 21.9 0.0 0.6 0.8 0.3 0.0 6.2 2.2 1.3 3.5 10.0 4.2 9.2 0.0 0.0 0.0 3.3 1.9 1.9 2.9 32.7 1.8 0.7 1.2 0.0 274.0 0.5 0.0 4.5 0.0 10.8 0.0 0.4 5.7 6.6 0.1 21.9 195.1 6.4 0.0 0.0 2.1 1.8 0.0 0.1 0.0 3.7 0.0 0.2 0.0 228.7 9.8 0.9 3.9 0.0 0.0 4.0 0.6 7.4 4.8 0.9 0.0 2.3 0.9 0.1 1.1 0.0 0.3 0.0 0.5 0.1 7.1 1.9 CNTN4 BIG-2 ENSG00000144619 "Contactin 4" Q8IWV2 3 2098813-3057959 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 411.7;Excitatory neurons: 960.7;Inhibitory neurons: 1048.5;Oligodendrocyte precursor cells: 248.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 8.3;CACO-2: 9.0;HEK 293: 5.5;SH-SY5Y: 16.5;WM-115: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 170000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.64e-1)" "unprognostic (7.17e-3)" "unprognostic (9.85e-2)" "unprognostic (5.75e-2)" "unprognostic (9.94e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-1)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (2.60e-2)" "unprognostic (7.38e-3)" "unprognostic (2.41e-2)" "prognostic favorable (1.00e-4)" "unprognostic (1.22e-2)" "unprognostic (2.88e-2)" "unprognostic (2.10e-1)" "unprognostic (2.13e-1)" 3.4 0.5 2.2 1.1 6.4 0.0 2.5 13.5 12.3 8.7 0.0 4.6 1.8 8.3 1.9 3.1 4.2 5.1 2.5 1.8 2.7 4.2 2.9 2.4 1.1 0.5 5.4 1.0 1.6 22.6 1.9 7.9 1.2 4.3 3.3 19.8 0.9 5.6 0.7 0.7 4.1 4.5 4.2 1.0 3.6 13.4 7.7 2.2 10.3 4.0 2.6 3.6 1.7 4.0 0.0 0.0 1.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 16.5 0.0 0.0 0.1 1.2 0.1 0.2 0.0 0.0 1.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 6.4 13.5 12.3 1.8 2.7 0.5 5.4 1.2 4.2 7.7 4.0 0.4 9.6 3.6 26.8 0.1 0.8 1.3 0.0 1.8 96.5 2.0 1.8 1.4 7.2 5.6 0.0 0.0 0.1 0.0 1.8 0.0 4.4 411.7 0.3 9.1 1.9 7.8 0.0 960.7 0.0 0.1 18.1 0.0 0.3 0.0 6.9 0.7 0.4 0.3 101.0 1048.5 2.0 0.0 0.3 0.7 156.3 5.0 0.4 1.8 31.9 0.0 27.5 0.0 248.3 14.7 0.0 1.6 5.3 0.4 0.4 3.7 3.7 0.0 5.9 6.6 0.5 8.3 4.5 4.9 0.9 0.0 0.3 0.1 0.1 3.5 0.2 CNTN5 "hNB-2, NB-2" ENSG00000149972 "Contactin 5" O94779 11 99020949-100358885 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.7;placenta: 2.6;salivary gland: 2.0;thyroid gland: 2.0" "Group enriched" "Detected in some" 14 "Excitatory neurons: 968.9;Inhibitory neurons: 2295.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039492, HPA041223" Approved "Intracellular and membrane" NA NA 480000 "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA039492: AB_10795108, HPA041223: AB_10794549" "unprognostic (2.09e-2)" "unprognostic (3.40e-1)" "unprognostic (8.99e-3)" "unprognostic (4.20e-2)" "unprognostic (6.51e-5)" "unprognostic (3.85e-2)" "unprognostic (9.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.02e-2)" "unprognostic (8.72e-2)" "unprognostic (5.48e-3)" "unprognostic (1.81e-2)" "unprognostic (1.76e-1)" "unprognostic (5.25e-2)" "unprognostic (1.25e-1)" 0.0 0.0 1.3 0.0 1.4 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 4.7 1.1 0.3 0.0 0.1 0.0 0.0 1.3 0.0 0.2 0.2 0.5 2.6 0.5 0.0 0.0 0.7 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.4 0.0 4.1 4.7 1.1 0.0 1.3 0.5 0.0 2.9 0.1 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.1 0.0 6.6 0.0 0.0 0.7 0.0 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.5 3.5 0.1 0.0 0.0 0.0 968.9 0.0 0.2 1.1 0.0 0.4 0.0 0.0 1.1 0.0 0.2 0.0 2295.2 0.0 2.0 0.0 0.0 0.4 0.9 0.0 0.0 42.2 0.0 0.1 0.0 112.1 23.2 0.1 0.0 1.9 0.0 0.0 0.0 0.2 12.5 0.7 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 CNTNAP2 "Caspr2, KIAA0868, NRXN4" ENSG00000174469 "Contactin associated protein 2" Q9UHC6 7 146116002-148420998 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Autism, Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 20.7;retina: 14.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3383.0;Inhibitory neurons: 6845.7" "Cancer enhanced" "Detected in many" "prostate cancer: 10.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 25 "B-cells: 2.5" "Cell line enhanced" "Detected in some" "AF22: 8.0;CACO-2: 6.7;NTERA-2: 12.0;SCLC-21H: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002739 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA002739: AB_1078545" "unprognostic (2.49e-2)" "unprognostic (1.49e-2)" "unprognostic (4.05e-1)" "unprognostic (3.08e-3)" "unprognostic (1.77e-1)" "unprognostic (2.29e-1)" "unprognostic (2.51e-2)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (3.67e-2)" "unprognostic (2.68e-1)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.00e-3)" 0.2 0.8 10.0 0.2 13.8 0.0 0.6 1.4 20.7 0.1 0.0 0.8 0.0 0.0 0.0 0.4 0.6 0.0 0.2 5.6 5.7 0.1 1.9 0.0 0.4 5.7 0.5 1.1 0.2 0.3 3.8 0.5 3.8 4.1 0.4 14.4 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.4 0.2 0.5 1.8 3.7 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 8.0 3.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 6.7 0.1 0.0 0.0 0.2 0.0 2.0 1.7 0.6 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.0 1.4 0.0 0.0 0.0 2.2 0.0 0.0 21.5 1.4 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.0 13.8 1.4 20.7 5.6 5.7 5.7 0.5 3.8 0.0 1.8 0.0 0.1 0.0 0.0 65.6 9.3 0.1 0.3 15.5 1.8 33.9 0.3 0.0 1.2 7.2 4.1 0.0 2.1 40.8 0.0 1.8 0.0 1.4 7.2 0.6 0.0 0.6 2.4 0.0 3383.0 0.7 6.8 1.1 0.5 0.7 0.0 0.2 0.0 8.9 3.3 1031.4 6845.7 3.9 0.0 0.6 2.0 2.7 1.2 0.4 0.0 180.8 0.2 8.2 1.0 429.3 914.7 4.1 2.1 0.0 0.3 7.4 4.7 0.5 0.9 16.7 0.0 0.0 0.9 2.4 12.0 9.1 0.0 6.3 0.0 1.2 6.8 0.2 CNTNAP3 "CASPR3, CNTNAP3A, FLJ14195, KIAA1714" ENSG00000106714 "Contactin associated protein family member 3" Q9BZ76 9 39072767-39288315 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 26.1;Excitatory neurons: 18.6;Hepatic stellate cells: 30.0;Inhibitory neurons: 103.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 20 "neutrophil: 7.3" "Lineage enriched" "Detected in single" 74 "granulocytes: 7.3" "Cell line enhanced" "Detected in many" "A549: 18.9;AF22: 22.5;TIME: 14.5;WM-115: 37.9" HPA047731 Uncertain "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA047731: AB_2680137" "unprognostic (9.06e-3)" "unprognostic (3.07e-2)" "unprognostic (5.74e-2)" "unprognostic (7.89e-2)" "unprognostic (7.03e-2)" "unprognostic (2.33e-3)" "unprognostic (4.58e-2)" "unprognostic (1.34e-2)" "unprognostic (1.51e-1)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (3.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.15e-2)" "unprognostic (1.20e-1)" "unprognostic (1.95e-3)" "unprognostic (1.93e-3)" 2.7 0.4 4.8 0.5 7.6 1.2 3.2 0.4 2.7 1.3 2.7 4.0 0.8 0.6 0.5 7.2 2.2 1.2 4.0 5.0 3.3 1.8 0.8 1.1 0.3 0.9 5.4 0.3 0.4 0.1 1.1 1.6 0.9 1.5 1.3 2.7 3.4 1.4 0.4 7.2 1.8 2.3 0.1 2.6 0.6 1.8 1.7 2.5 1.2 0.7 0.6 1.0 2.5 2.8 1.1 18.9 22.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 0.0 1.4 4.7 1.9 4.4 0.0 0.0 1.6 0.0 5.2 0.5 0.2 0.3 0.0 0.5 4.1 0.0 1.7 9.4 8.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.9 0.2 5.7 0.0 0.6 5.4 0.4 0.8 2.1 0.7 6.7 0.0 3.7 2.4 0.0 3.2 14.5 0.0 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 37.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 4.8 7.6 0.4 2.7 5.0 3.3 0.9 5.4 0.9 0.1 1.7 2.8 8.0 3.2 1.7 26.1 0.0 6.2 4.0 1.8 18.2 1.3 0.9 3.0 3.5 4.3 1.5 1.8 2.1 0.8 0.0 0.1 0.0 0.4 1.9 1.4 0.7 7.5 3.5 0.0 18.6 0.2 2.5 1.2 0.0 0.2 0.0 0.1 30.0 1.3 0.1 0.0 103.1 0.3 0.0 1.6 0.8 0.9 0.3 0.2 0.0 13.1 0.0 10.5 0.0 3.0 13.3 0.7 0.0 0.0 1.2 1.4 0.0 1.9 4.1 0.7 0.0 0.5 0.9 1.7 8.8 10.4 7.7 0.7 0.4 0.0 0.1 2.7 CNTNAP3B ENSG00000154529 "Contactin associated protein family member 3B" Q96NU0 9 41890314-42129510 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 69.6;Hepatic stellate cells: 91.8;Inhibitory neurons: 161.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 3.7" "Lineage enriched" "Detected in single" 38 "granulocytes: 3.7" "Cell line enhanced" "Detected in many" "A549: 29.9;AF22: 41.8;WM-115: 28.5" HPA047731 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA047731: AB_2680137" "unprognostic (2.68e-2)" "unprognostic (9.63e-3)" "unprognostic (2.20e-2)" "unprognostic (2.87e-1)" "unprognostic (1.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.20e-3)" "unprognostic (5.70e-2)" "unprognostic (2.27e-1)" "unprognostic (7.20e-2)" "unprognostic (3.74e-3)" "unprognostic (1.64e-1)" "unprognostic (7.74e-2)" "unprognostic (5.78e-3)" "unprognostic (7.93e-3)" "unprognostic (2.90e-2)" "unprognostic (2.05e-4)" 8.9 1.6 6.1 1.4 10.0 0.3 10.1 2.9 6.3 3.7 6.4 8.6 1.4 2.5 0.7 9.3 5.0 2.5 5.7 7.1 7.4 7.0 2.6 3.4 1.0 4.7 9.0 1.1 1.5 0.4 2.9 3.8 4.4 2.8 2.8 6.3 6.6 2.1 1.6 8.8 3.7 3.2 2.5 3.8 2.1 1.9 5.1 2.4 2.1 1.6 1.1 3.2 4.2 3.4 0.2 29.9 41.8 0.0 1.3 0.5 0.1 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.7 0.1 0.6 3.7 2.4 2.3 0.0 0.1 1.3 0.0 5.4 2.6 0.9 1.4 0.0 3.3 3.4 0.4 0.5 10.4 7.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 4.1 1.0 9.0 0.0 0.7 11.9 1.4 0.8 3.0 0.3 1.1 0.0 5.8 1.3 0.0 4.2 7.4 0.2 2.8 0.1 0.8 0.0 0.0 0.0 0.0 1.3 28.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 6.1 10.0 2.9 6.3 7.1 7.4 4.7 9.0 4.4 2.5 5.1 3.4 69.6 0.0 6.3 34.6 0.6 4.2 7.8 2.4 15.4 2.6 3.9 11.8 7.1 4.3 1.2 3.7 0.0 3.1 0.3 0.3 0.0 2.1 2.0 2.8 0.3 35.0 1.8 2.7 34.6 3.3 2.1 6.2 0.0 1.3 1.3 0.4 91.8 7.5 0.1 0.0 161.6 1.6 6.1 3.8 0.8 1.4 0.9 0.5 5.4 33.7 0.0 27.9 0.0 8.0 1.3 2.0 0.0 0.7 0.0 3.2 0.0 9.7 11.1 1.0 0.0 0.7 3.6 0.8 7.0 8.4 5.3 0.7 0.7 0.2 0.1 6.0 CNTNAP3C ENSG00000283378 "Contactin associated protein family member 3C" 9 61330717-61453030 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 11.0;brain: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 12 "neutrophil: 30.9" "Lineage enriched" "Detected in single" 182 "granulocytes: 30.9" "Cell line enhanced" "Detected in some" "A549: 27.5;SiHa: 6.1;TIME: 8.7;WM-115: 24.0" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 17: WM-115 - Nervous system development" 0.2 0.0 1.8 0.1 3.2 11.0 0.2 0.2 0.9 0.2 2.6 0.2 0.0 0.0 0.0 0.5 0.1 0.0 0.9 2.1 1.3 0.1 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.4 0.1 0.0 1.1 0.2 0.2 0.0 0.4 0.0 0.4 0.4 0.1 0.2 0.0 0.0 0.0 0.3 0.8 1.3 27.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.9 3.0 0.4 2.1 0.0 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.6 1.8 1.7 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.6 0.0 0.9 0.0 0.5 3.3 0.0 0.9 0.4 0.8 6.1 0.1 1.7 0.3 0.1 0.1 8.7 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 24.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.9 0.0 0.0 0.0 0.0 0.0 1.8 3.2 0.2 0.9 2.1 1.3 0.0 1.5 0.2 0.0 0.4 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 COASY "DPCK, NBP, PPAT" ENSG00000068120 "Coenzyme A synthase" Q13057 17 42561467-42566277 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022875, HPA022912, HPA023273" Approved "Intracellular and membrane" NA NA 20000 "Cluster 44: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 40: Granulosa cells - Unknown function" "HPA022875: AB_1847066, HPA022912: AB_1847067, HPA023273: AB_1847068" "unprognostic (2.83e-1)" "unprognostic (8.35e-2)" "unprognostic (1.81e-1)" "prognostic favorable (2.15e-4)" "unprognostic (1.01e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (7.54e-5)" "unprognostic (4.06e-2)" "unprognostic (3.36e-2)" "unprognostic (2.50e-2)" "unprognostic (1.50e-1)" "unprognostic (7.83e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (5.55e-1)" "unprognostic (1.62e-1)" "unprognostic (2.16e-1)" 27.4 60.0 24.0 23.1 24.0 29.5 32.8 24.7 28.1 27.6 26.7 35.6 43.3 25.2 17.2 54.4 29.8 16.9 29.4 25.4 23.9 45.6 70.9 30.3 25.0 27.8 24.7 26.0 59.0 39.0 30.3 25.5 28.1 32.4 24.3 13.3 58.5 28.7 38.6 46.6 36.9 17.2 23.8 35.9 47.2 32.4 25.7 27.6 39.0 25.3 25.2 26.8 31.1 24.6 94.2 149.1 27.2 55.2 55.5 34.8 89.2 38.3 52.9 65.8 46.5 85.7 89.2 52.7 65.6 50.4 69.5 146.9 66.1 81.4 43.7 47.6 122.2 52.5 91.2 140.9 70.2 56.4 73.1 51.5 97.8 62.4 66.6 52.4 63.2 70.5 98.7 70.8 46.6 59.2 71.5 87.2 36.7 125.8 75.1 39.1 93.5 88.1 89.9 66.7 63.3 50.1 34.9 37.3 75.4 52.2 158.0 70.4 41.6 68.3 62.3 52.4 40.1 84.6 127.4 31.0 80.9 55.3 47.5 23.3 29.8 26.8 19.7 31.8 20.5 15.8 15.8 19.1 33.6 15.7 15.7 16.3 19.5 21.0 22.5 23.6 18.1 24.0 24.0 24.0 24.7 28.1 25.4 23.9 27.8 24.7 28.1 23.8 25.7 24.6 15.4 6.4 23.8 9.8 24.1 15.0 21.7 49.5 25.6 17.8 38.2 22.9 22.9 40.0 33.3 71.7 0.0 89.4 21.2 53.7 33.2 44.8 4.4 31.5 20.6 20.6 17.4 30.3 5.6 52.5 51.6 18.7 40.2 28.0 10.2 101.2 23.9 94.2 40.3 33.7 5.7 36.7 42.7 23.6 16.1 7.7 14.9 19.9 14.2 4.7 36.2 29.4 20.6 3.5 5.9 38.9 32.4 16.6 25.3 31.2 66.3 94.8 36.5 18.0 26.3 15.2 18.6 46.7 31.1 33.4 17.8 77.2 16.9 36.6 45.1 30.7 COCH "COCH-5B2, DFNA31, DFNA9" ENSG00000100473 Cochlin O43405 14 30874514-30895065 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "pancreas: 502.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 63.0;Horizontal cells: 84.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 71.3" "Group enriched" "Detected in some" 12 "memory B-cell: 38.3;naive B-cell: 17.7" "Lineage enriched" "Detected in many" 17 "B-cells: 38.3" "Cell line enhanced" "Detected in many" "HEK 293: 95.7;Hep G2: 63.8;K-562: 129.1;NB-4: 105.5;SCLC-21H: 111.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 50.8" HPA065086 Supported Vesicles "Secreted in other tissues" NA NA 160000 "Cluster 19: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 1: K-562 - Erythropoiesis" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA065086: " "unprognostic (8.36e-3)" "unprognostic (2.51e-2)" "unprognostic (8.61e-2)" "unprognostic (1.64e-2)" "unprognostic (6.48e-2)" "unprognostic (6.53e-2)" "unprognostic (9.61e-2)" "unprognostic (4.03e-1)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" "unprognostic (1.27e-2)" "unprognostic (2.91e-3)" "unprognostic (5.42e-3)" "unprognostic (3.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.72e-1)" 3.2 3.7 7.3 2.8 71.3 4.0 3.4 1.4 20.9 17.4 19.0 3.2 0.8 0.6 2.2 0.9 6.2 2.9 1.9 5.6 8.0 5.2 0.5 0.6 11.0 2.9 7.9 0.8 502.0 3.4 10.1 1.9 3.7 48.3 2.2 12.1 3.6 73.4 1.3 15.2 2.6 1.1 6.2 2.6 1.7 5.2 12.5 1.3 1.3 5.0 7.7 2.0 23.0 1.7 0.0 35.3 3.1 0.0 0.6 0.1 21.8 0.2 0.0 6.4 17.1 20.9 1.2 0.4 1.7 0.0 1.3 0.1 22.2 0.0 10.6 0.0 95.7 18.1 7.6 63.8 0.0 1.8 7.3 1.3 0.0 0.6 0.0 0.0 0.3 39.9 129.1 5.1 1.6 0.8 9.2 105.5 11.9 0.1 3.7 26.7 0.0 0.9 1.1 3.4 111.8 30.4 2.6 0.6 0.2 12.1 0.0 48.7 0.9 0.0 0.0 0.3 0.1 5.7 15.8 11.2 0.0 0.0 4.7 0.0 0.6 0.0 0.0 0.0 0.0 38.3 0.3 0.0 0.1 17.7 0.0 0.1 0.2 0.0 0.0 0.0 2.2 1.0 7.3 71.3 1.4 20.9 5.6 8.0 2.9 7.9 3.7 6.2 12.5 1.7 2.0 0.0 0.5 3.6 13.4 19.1 2.3 0.3 0.0 2.7 7.9 1.5 0.8 2.8 0.9 0.0 4.2 6.5 1.3 0.6 1.9 0.5 1.5 2.2 0.8 3.1 17.0 7.4 14.3 63.0 14.3 22.0 1.1 1.0 1.3 1.8 5.0 5.0 3.8 84.1 24.2 0.3 6.1 5.0 25.2 2.0 1.5 2.4 19.6 7.5 2.8 14.5 0.0 6.0 16.5 3.7 4.3 6.0 10.0 3.5 0.2 11.7 0.5 4.0 0.0 2.8 9.0 22.1 20.3 0.1 13.5 6.6 3.3 0.1 0.6 1.7 COG1 "KIAA1381, LDLB" ENSG00000166685 "Component of oligomeric golgi complex 1" Q8WTW3 17 73192632-73208507 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029224 Supported NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "HPA029224: AB_10600698" "unprognostic (8.93e-2)" "unprognostic (4.36e-2)" "unprognostic (2.44e-2)" "unprognostic (3.10e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-2)" "prognostic unfavorable (2.91e-6)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (1.05e-3)" "unprognostic (5.31e-3)" "unprognostic (9.94e-3)" "unprognostic (2.63e-2)" "unprognostic (2.57e-1)" "unprognostic (1.08e-1)" "unprognostic (2.06e-1)" "unprognostic (2.21e-1)" 23.9 23.4 37.1 11.1 39.6 15.8 21.0 29.0 41.1 23.0 26.4 24.6 16.2 21.7 17.6 13.2 20.4 12.1 43.5 42.0 31.9 17.4 15.4 15.3 12.1 26.0 28.0 23.7 27.5 17.6 33.0 13.5 29.2 19.3 19.6 25.3 18.9 17.4 52.5 20.7 19.9 18.8 25.5 17.4 20.9 15.9 31.4 13.6 17.7 31.8 12.7 21.1 17.4 32.2 25.3 19.1 16.1 17.3 25.9 24.5 19.8 34.8 29.5 32.0 29.9 16.6 16.1 14.0 19.2 33.0 29.5 15.6 16.4 24.2 46.9 6.1 18.3 12.5 19.5 30.1 27.4 15.4 14.2 20.9 18.4 25.7 24.7 21.5 30.3 18.7 14.1 20.5 32.7 24.6 21.3 12.2 4.9 24.5 34.2 14.9 27.3 17.2 19.7 16.1 17.5 23.8 16.6 22.9 18.0 30.4 33.4 11.2 17.5 36.7 28.1 24.9 28.0 26.9 13.0 15.3 15.8 10.1 14.6 8.6 9.6 18.1 15.7 12.3 17.2 12.5 17.7 16.8 11.8 7.3 16.0 17.9 7.5 17.3 9.5 6.4 14.0 11.8 37.1 39.6 29.0 41.1 42.0 31.9 26.0 28.0 29.2 25.5 31.4 32.2 17.8 6.4 9.6 9.8 12.0 4.0 6.8 7.8 8.6 21.9 7.8 6.5 5.1 14.3 18.0 9.2 33.3 19.8 9.4 12.5 1.9 11.4 17.2 17.1 9.0 11.2 17.4 9.9 28.3 11.8 10.8 10.9 19.4 13.9 18.3 16.4 8.6 9.5 8.5 28.6 17.2 18.7 18.3 3.2 4.3 16.3 12.2 5.7 5.4 10.3 11.0 16.6 21.6 13.0 9.9 11.0 12.5 15.8 17.2 7.0 13.2 11.2 22.7 28.6 13.1 15.9 11.7 19.5 13.0 6.2 3.4 16.3 15.0 15.4 10.5 6.4 COL10A1 ENSG00000123500 "Collagen type X alpha 1 chain" Q03692 6 116118909-116158747 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.5;choroid plexus: 39.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 26.6;Inhibitory neurons: 6.3;Microglial cells: 8.4;Oligodendrocytes: 27.9" "Cancer enhanced" "Detected in many" "breast cancer: 42.8;pancreatic cancer: 51.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTEC/SVTERT24-B: 39.7" "Low region specificity" "Detected in many" HPA053268 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA053268: " "unprognostic (3.83e-2)" "unprognostic (6.81e-2)" "unprognostic (7.20e-2)" "unprognostic (7.45e-3)" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (3.84e-2)" "unprognostic (1.49e-1)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" "unprognostic (4.37e-2)" "unprognostic (7.03e-2)" "unprognostic (1.38e-11)" "unprognostic (2.16e-3)" "unprognostic (7.22e-2)" "unprognostic (3.60e-1)" "unprognostic (2.06e-3)" 0.3 0.0 2.2 0.2 8.6 0.3 0.3 4.6 4.5 1.2 39.9 0.2 0.0 0.3 0.0 0.0 0.0 8.9 0.3 1.3 3.3 0.4 0.2 2.8 0.6 7.7 5.6 3.9 3.3 2.5 0.4 0.1 7.1 1.9 0.1 0.9 2.6 0.8 0.1 0.4 0.1 0.5 4.3 2.5 0.1 0.2 6.3 0.1 0.7 0.0 1.9 0.2 0.1 15.5 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.2 2.9 0.4 6.0 0.1 0.0 0.1 0.0 1.0 0.0 0.7 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.8 0.0 39.7 0.0 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.2 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.0 6.3 0.1 0.4 0.5 0.0 0.0 0.1 0.6 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 8.6 4.6 4.5 1.3 3.3 7.7 5.6 7.1 4.3 6.3 15.5 2.6 0.0 0.6 3.9 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.1 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.4 26.6 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 6.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.4 0.0 2.2 0.0 2.5 27.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.2 5.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 COL11A1 "CO11A1, COLL6, DFNA37, STL2" ENSG00000060718 "Collagen type XI alpha 1 chain" P12107 1 102876467-103108872 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 20.1;retina: 9.6" "Cell type enhanced" "Detected in some" "Astrocytes: 83.9;Excitatory neurons: 99.5;Oligodendrocyte precursor cells: 557.4;Theca cells: 139.6" "Cancer enhanced" "Detected in many" "breast cancer: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 116.9;BJ: 43.2;BJ hTERT+ SV40 Large T+ RasG12V: 85.3;HBF TERT88: 48.7;HSkMC: 142.5;SuSa: 60.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058335 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 640000 "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Endoplasmic reticulum" "HPA058335: AB_2683682" "unprognostic (2.60e-3)" "unprognostic (6.61e-4)" "unprognostic (9.58e-2)" "unprognostic (5.06e-5)" "unprognostic (2.83e-1)" "unprognostic (2.85e-2)" "unprognostic (6.03e-3)" "unprognostic (2.23e-3)" "unprognostic (9.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-2)" "unprognostic (1.94e-2)" "unprognostic (3.01e-12)" "unprognostic (1.27e-2)" "unprognostic (3.53e-1)" "unprognostic (3.54e-2)" "unprognostic (2.32e-2)" 0.6 0.6 4.3 0.3 3.1 0.0 0.4 1.6 4.6 0.9 2.8 0.4 0.1 0.5 0.1 0.0 0.0 3.1 0.0 2.4 2.5 0.1 0.0 0.3 0.1 2.5 3.7 0.6 0.7 0.2 3.3 20.1 2.2 0.2 0.3 9.6 1.5 0.8 0.1 1.4 0.1 0.3 1.0 0.5 0.1 1.4 2.2 0.0 0.1 0.1 0.0 0.2 0.1 2.1 0.0 0.8 116.9 0.0 4.6 5.9 0.0 43.2 16.1 23.3 85.3 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 142.5 0.0 1.1 0.0 17.7 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.0 8.1 0.0 0.1 0.0 7.4 0.0 15.2 0.0 0.1 0.0 0.0 0.1 0.0 60.5 0.0 0.1 0.0 0.6 27.0 0.0 4.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 3.1 1.6 4.6 2.4 2.5 2.5 3.7 2.2 1.0 2.2 2.1 0.0 0.0 2.2 83.9 0.0 1.8 0.0 0.0 0.0 9.4 0.1 4.2 0.5 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 21.0 0.1 0.9 2.2 0.0 0.0 99.5 0.0 0.8 18.7 0.0 0.0 2.5 8.3 0.0 0.0 0.3 0.0 32.9 0.0 0.0 0.0 1.3 4.0 1.2 0.2 10.6 29.0 0.0 29.8 0.0 557.4 6.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.9 2.6 0.5 0.8 0.0 1.1 0.3 0.2 139.6 0.0 0.0 COL11A2 "DFNA13, DFNB53, HKE5" ENSG00000204248 "Collagen type XI alpha 2 chain" P13942 6 33162681-33192499 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "pituitary gland: 23.5;testis: 8.1" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Early spermatids: 10.8;Muller glia cells: 5.2;Oligodendrocytes: 6.7" "Cancer enriched" "Detected in many" 8 "melanoma: 13.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 2100000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.62e-1)" "unprognostic (8.69e-2)" "unprognostic (1.65e-4)" "unprognostic (5.15e-3)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (1.04e-2)" "unprognostic (9.67e-2)" "unprognostic (2.05e-2)" "unprognostic (4.47e-2)" "unprognostic (1.22e-1)" "unprognostic (3.41e-3)" "unprognostic (2.26e-6)" "unprognostic (8.27e-2)" "unprognostic (2.17e-1)" "unprognostic (1.88e-1)" "unprognostic (5.96e-2)" 1.0 0.3 0.3 0.0 0.6 0.0 0.9 0.5 0.6 1.6 0.0 0.7 0.2 1.2 0.2 0.5 0.9 0.1 1.8 0.3 0.3 1.3 0.8 1.0 0.0 0.5 0.4 1.1 0.6 0.1 23.5 0.0 0.5 1.3 0.0 0.1 0.8 0.1 1.3 0.6 0.7 0.1 0.5 1.2 0.7 8.1 0.5 0.3 3.5 0.7 0.0 0.6 0.9 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.2 0.2 0.0 0.0 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.5 0.6 0.3 0.3 0.5 0.4 0.5 0.5 0.5 0.8 2.6 0.0 0.0 8.5 0.1 1.5 0.2 0.1 1.8 2.8 1.2 1.8 2.3 0.0 0.1 0.0 4.2 0.0 0.6 0.3 0.0 0.1 10.8 0.2 0.6 1.5 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.5 0.0 0.6 4.6 0.2 0.2 0.0 3.7 0.1 0.0 0.6 0.4 1.9 0.0 0.3 1.8 1.0 0.0 5.2 0.0 3.5 6.7 0.1 0.6 0.4 0.8 0.2 0.0 0.1 0.0 1.1 0.0 0.7 1.8 0.9 2.1 0.7 1.1 0.0 0.4 0.2 0.5 0.1 COL12A1 COL12A1L ENSG00000111799 "Collagen type XII alpha 1 chain" Q99715 6 75084326-75206267 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Endometrial stromal cells: 44.3;Excitatory neurons: 52.9;Fibroblasts: 99.7;Leydig cells: 60.3;Sertoli cells: 46.0;Smooth muscle cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "fHDF/TERT166: 1432.1;SiHa: 846.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 29.1" "HPA009143, HPA010021" Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 9100000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "HPA009143: AB_1847095, HPA010021: " "unprognostic (2.60e-2)" "unprognostic (2.80e-3)" "unprognostic (7.92e-2)" "unprognostic (8.27e-3)" "unprognostic (1.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (3.47e-3)" "unprognostic (1.38e-1)" "unprognostic (4.30e-1)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "prognostic unfavorable (1.69e-9)" "unprognostic (1.03e-3)" "unprognostic (1.81e-1)" "unprognostic (3.16e-3)" "unprognostic (1.92e-2)" 105.1 15.7 2.2 16.0 1.9 0.0 65.4 0.8 2.7 112.8 0.4 74.9 8.7 124.5 5.5 36.2 42.2 20.9 25.5 1.0 1.2 25.9 3.5 24.6 7.2 1.8 4.8 123.2 5.9 5.0 4.8 1.8 0.6 20.8 17.2 0.4 16.1 42.4 14.4 48.9 40.6 72.1 0.6 11.4 18.1 4.6 2.0 5.5 19.3 12.5 4.2 26.3 45.8 0.8 0.2 2.2 11.5 0.2 270.2 162.0 28.3 275.4 229.3 186.2 257.3 27.5 0.7 0.0 27.7 1432.1 3.9 59.2 0.5 28.7 174.6 0.2 1.4 0.2 101.1 0.1 97.9 0.3 0.2 234.9 5.0 42.2 50.6 173.6 32.0 0.1 0.0 0.0 29.4 0.2 0.1 0.2 6.4 0.0 15.3 0.1 23.1 0.2 8.9 14.4 0.0 0.0 846.1 21.2 0.3 15.5 131.8 0.5 0.2 78.5 97.0 41.5 91.4 0.1 0.1 0.4 26.4 0.3 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 0.8 2.7 1.0 1.2 1.8 4.8 0.6 0.6 2.0 0.8 14.2 76.9 5.1 2.3 0.0 20.6 0.6 12.7 5.2 0.4 4.7 7.1 4.1 0.0 4.7 3.7 0.0 0.6 0.0 0.0 0.0 1.4 24.1 6.3 44.3 11.0 0.0 0.0 52.9 4.6 1.3 99.7 2.6 14.1 1.3 0.1 3.3 0.0 0.8 0.0 32.4 0.0 0.0 0.3 18.4 14.7 60.3 1.8 21.4 38.4 0.0 0.0 0.0 19.6 1.2 6.7 0.0 13.2 0.1 1.7 0.0 0.9 1.7 0.0 46.0 20.0 48.6 0.3 0.6 0.6 13.1 0.7 2.5 1.4 0.1 0.3 COL13A1 ENSG00000197467 "Collagen type XIII alpha 1 chain" Q5TAT6 10 69801880-69964275 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Osteogenesis" "Developmental protein, Heparin-binding" "Congenital myasthenic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 30.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 10.1;granulocytes: 20.3;Melanocytes: 5.4;Microglial cells: 6.5;NK-cells: 9.2;Smooth muscle cells: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 63.6;BJ hTERT+: 61.6;hTERT-RPE1: 83.7;HUVEC TERT2: 102.2;PC-3: 93.1;TIME: 137.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA050392 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA050392: AB_2681110" "unprognostic (2.79e-2)" "unprognostic (2.82e-3)" "unprognostic (1.38e-1)" "unprognostic (3.86e-1)" "unprognostic (4.67e-4)" "unprognostic (3.13e-1)" "unprognostic (1.69e-1)" "unprognostic (7.43e-2)" "unprognostic (6.16e-3)" "unprognostic (1.22e-1)" "unprognostic (2.60e-1)" "unprognostic (2.53e-2)" "unprognostic (1.36e-5)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (1.52e-2)" "unprognostic (3.93e-2)" 1.2 1.9 1.5 2.6 1.7 0.3 2.0 9.5 3.3 5.7 1.9 4.6 2.9 1.8 30.4 1.9 2.8 2.4 3.4 1.4 1.5 2.0 0.8 10.9 0.9 1.6 1.6 0.9 2.1 0.8 3.7 1.7 1.8 13.6 3.4 0.0 0.7 8.0 0.9 5.2 3.8 2.9 1.6 8.0 6.2 0.7 1.7 0.3 1.5 1.4 0.8 3.8 1.8 1.5 1.5 0.6 22.1 0.0 0.1 4.3 0.1 63.6 61.6 10.9 5.5 0.0 1.4 0.2 10.5 30.1 1.0 2.3 0.0 0.2 18.9 0.0 1.6 0.0 0.0 0.0 2.9 0.0 0.1 9.8 0.1 27.5 9.0 83.7 102.2 0.0 0.0 0.1 10.4 0.4 0.0 0.2 5.3 0.0 93.1 0.1 0.0 10.3 0.4 0.0 2.4 0.0 0.0 0.2 3.4 0.9 0.0 0.2 137.4 0.3 17.1 5.7 45.7 13.4 0.0 0.1 37.2 0.1 51.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.5 1.7 9.5 3.3 1.4 1.5 1.6 1.6 1.8 1.6 1.7 1.5 0.9 0.0 0.6 0.3 0.0 3.4 0.3 0.3 0.6 0.2 0.1 2.0 2.1 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 1.3 0.0 0.0 0.2 3.4 0.0 0.0 1.4 0.0 0.0 10.1 0.0 0.1 20.3 1.8 1.1 0.0 0.1 0.0 0.3 0.0 0.0 0.3 2.3 0.0 0.0 0.3 5.4 6.5 0.0 0.1 9.2 0.0 0.3 0.1 0.0 0.4 0.3 0.5 0.9 0.0 0.1 0.0 0.0 1.1 5.6 0.5 0.5 0.2 3.0 0.1 0.6 0.5 0.1 0.1 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL15A1 ENSG00000204291 "Collagen type XV alpha 1 chain" P39059 9 98943179-99070792 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 229.2" "Cell type enhanced" "Detected in many" "Adipocytes: 307.0;Endothelial cells: 190.5;Fibroblasts: 202.3;Leydig cells: 326.8;Peritubular cells: 483.3;Theca cells: 333.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 26.4;BJ hTERT+: 55.6;HDLM-2: 24.5;K-562: 18.8;U-2197: 45.6;U-87 MG: 20.6;WM-115: 31.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "spinal cord: 44.3" "HPA017913, HPA017915" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 28000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA017913: AB_1847099, HPA017915: AB_1847100" "unprognostic (4.30e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-2)" "unprognostic (2.09e-1)" "unprognostic (1.09e-2)" "prognostic favorable (5.47e-4)" "unprognostic (3.08e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-1)" "unprognostic (1.84e-1)" "unprognostic (7.87e-2)" "unprognostic (1.20e-3)" "unprognostic (3.66e-3)" "unprognostic (8.98e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (3.08e-4)" 84.7 36.9 0.6 50.6 0.9 0.1 46.7 0.8 1.0 31.2 4.0 44.5 12.9 53.8 19.2 26.9 17.3 42.8 58.0 0.4 0.8 12.9 1.0 11.1 10.4 0.6 0.9 23.2 26.8 11.8 6.0 229.2 0.7 21.6 16.3 0.0 35.9 14.3 56.5 15.1 17.7 108.9 0.6 3.7 27.3 27.0 2.4 13.0 21.1 34.4 8.6 42.1 15.1 0.7 0.0 0.0 0.1 0.0 4.6 2.6 0.1 26.4 55.6 1.4 0.5 0.0 0.0 0.2 0.7 5.8 0.2 0.1 0.0 0.0 0.2 24.5 0.0 0.3 12.9 0.0 1.1 0.4 2.5 7.6 0.0 6.0 0.2 0.0 0.0 0.0 18.8 0.0 2.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 14.7 0.2 0.0 0.0 0.1 0.1 0.8 3.9 7.4 0.3 0.2 0.6 0.0 0.1 0.6 45.6 0.5 0.2 0.0 0.0 20.6 0.2 31.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.9 0.8 1.0 0.4 0.8 0.6 0.9 0.7 0.6 2.4 0.7 307.0 0.0 0.0 0.7 0.5 19.5 0.1 0.0 5.2 0.0 2.6 4.1 8.1 0.0 0.0 0.0 0.0 3.8 1.8 0.0 0.0 2.4 5.7 3.9 103.4 190.5 0.0 0.0 0.4 0.8 3.7 202.3 0.5 2.2 0.0 0.3 0.0 0.0 7.6 0.0 2.9 0.0 0.0 0.3 27.2 22.5 326.8 3.1 17.8 46.9 0.6 0.0 1.0 1.0 0.3 0.6 0.0 483.3 0.3 1.2 0.0 0.5 0.0 0.0 13.1 107.8 52.8 1.9 1.2 1.3 16.3 7.7 2.1 333.4 0.0 0.7 COL16A1 ENSG00000084636 "Collagen type XVI alpha 1 chain" Q07092 1 31652263-31704319 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 109.0;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 122.0;Peritubular cells: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 133.1;ASC TERT1: 102.9;BJ hTERT+: 115.9;fHDF/TERT166: 106.5;HSkMC: 98.7;U-2197: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027237 Uncertain "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 960000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA027237: AB_10600699" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (5.64e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (2.04e-1)" "unprognostic (4.48e-3)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (4.00e-9)" "unprognostic (9.62e-2)" "unprognostic (6.13e-2)" "unprognostic (4.60e-2)" "unprognostic (2.15e-2)" 33.6 17.3 19.0 14.4 44.7 0.3 41.0 35.9 32.4 169.7 7.6 78.9 14.8 93.6 23.7 22.4 37.4 39.4 33.6 18.9 29.8 11.5 3.2 31.1 8.5 55.5 43.2 177.9 7.8 3.5 28.6 21.1 48.6 102.8 10.9 8.8 35.5 91.3 8.4 69.3 35.8 56.2 34.0 9.9 42.1 40.9 40.3 5.6 46.8 7.4 4.1 106.9 86.8 57.5 0.1 2.0 0.0 0.1 133.1 102.9 14.6 60.5 115.9 15.1 16.1 0.4 11.0 0.0 1.9 106.5 2.3 48.3 0.0 65.8 3.5 0.0 0.2 0.0 8.1 21.3 45.1 0.0 0.3 98.7 44.6 43.2 22.7 3.8 0.1 0.3 0.0 0.2 2.1 0.0 0.1 0.5 0.1 0.4 0.2 0.2 1.3 0.4 0.0 0.4 1.5 2.7 7.3 1.2 9.6 0.5 1.2 0.0 0.2 52.3 52.5 92.1 1.3 0.1 0.2 0.0 36.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 44.7 35.9 32.4 18.9 29.8 55.5 43.2 48.6 34.0 40.3 57.5 4.3 9.6 3.9 109.0 0.1 30.7 14.8 37.5 15.9 2.4 7.9 21.3 8.4 0.0 9.8 18.4 2.1 1.9 0.6 2.0 0.0 4.6 13.6 2.6 11.5 2.8 27.6 0.4 23.9 0.7 3.8 54.3 8.2 2.4 7.0 0.2 5.0 0.0 1.3 0.0 8.2 30.9 8.2 0.6 11.4 26.8 43.8 0.7 14.2 10.3 0.0 31.3 0.0 62.4 122.0 1.2 4.7 91.4 0.3 9.3 16.8 2.1 15.0 2.5 0.0 5.4 25.0 14.9 3.8 1.9 21.2 2.2 2.2 0.5 6.8 15.3 COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 479.6;Sertoli cells: 223.5;Smooth muscle cells: 268.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 139.0;EFO-21: 309.4;NTERA-2: 170.6;RPTEC TERT1: 131.6;TIME: 186.0" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 290000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" 136.4 87.6 14.5 33.9 22.3 15.9 97.1 26.4 21.8 229.4 34.4 91.2 30.4 135.6 35.4 50.1 118.3 28.9 122.2 15.7 18.1 218.2 561.9 83.2 19.8 43.7 28.6 257.3 102.3 7.9 106.5 40.7 39.1 91.0 5.5 5.4 35.8 46.8 26.5 77.8 65.7 28.5 26.6 86.8 44.5 30.0 27.0 9.0 101.1 7.4 7.2 109.8 112.2 45.4 10.5 84.0 20.6 18.0 38.6 31.9 3.3 82.0 139.0 39.1 10.5 48.8 28.9 1.5 309.4 82.8 21.6 37.9 4.6 5.0 7.4 0.7 20.0 47.9 1.4 69.6 37.3 0.7 4.4 37.6 3.3 3.8 4.5 8.5 121.3 0.5 49.6 0.3 14.4 16.7 0.8 3.2 170.6 3.2 30.7 0.7 12.6 4.0 131.6 1.3 22.8 16.3 7.6 7.8 26.6 73.0 7.5 9.9 186.0 0.5 11.4 0.4 17.7 0.4 0.8 1.5 0.1 1.7 32.7 0.8 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.2 3.2 0.0 0.0 0.1 0.0 0.1 14.5 22.3 26.4 21.8 15.7 18.1 43.7 28.6 39.1 26.6 27.0 45.4 156.9 0.0 4.1 6.5 3.9 67.7 15.5 19.0 67.7 13.5 9.3 32.1 15.7 61.5 5.0 112.2 4.2 1.9 3.4 0.1 9.8 117.5 1.5 58.3 99.5 91.2 0.0 33.0 4.9 5.8 1.1 101.1 3.6 144.2 57.8 6.6 75.0 479.6 2.4 0.0 15.8 0.1 4.1 12.1 32.5 6.7 79.9 6.5 49.8 82.4 3.2 141.9 7.2 4.0 28.0 9.9 0.0 126.0 4.6 14.0 0.0 72.9 0.7 6.3 223.5 138.2 268.6 4.1 6.0 7.9 28.6 2.5 15.3 47.5 0.4 2.6 COL19A1 ENSG00000082293 "Collagen type XIX alpha 1 chain" Q14993 6 69866556-70212468 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.1;lymphoid tissue: 3.2" "Cell type enhanced" "Detected in some" "B-cells: 33.5;Excitatory neurons: 66.6;Inhibitory neurons: 164.2;Oligodendrocyte precursor cells: 39.7" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Region enhanced" "Detected in many" "cerebellum: 9.1" "Group enriched" "Detected in some" 218 "memory B-cell: 14.6;naive B-cell: 31.9" "Lineage enriched" "Detected in single" 299 "B-cells: 31.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.3;RH-30: 11.4;SCLC-21H: 3.7;SH-SY5Y: 2.9;SK-MEL-30: 9.6;WM-115: 9.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA042422 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042422: AB_10794798" "unprognostic (2.65e-2)" "unprognostic (2.55e-1)" "unprognostic (2.71e-1)" "unprognostic (9.24e-2)" "unprognostic (2.26e-2)" "unprognostic (6.20e-2)" "unprognostic (3.17e-1)" "unprognostic (1.10e-3)" "unprognostic (3.41e-1)" "unprognostic (1.28e-1)" "unprognostic (2.76e-1)" "unprognostic (1.62e-2)" "unprognostic (1.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.20e-1)" "unprognostic (3.35e-1)" "unprognostic (8.91e-2)" 0.0 0.1 1.2 1.5 1.6 0.3 0.0 9.1 1.9 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.1 0.1 0.7 2.3 0.1 1.4 0.1 0.0 2.6 0.2 0.2 0.0 0.2 0.0 0.6 0.0 0.3 0.7 0.7 0.6 0.1 0.0 0.7 0.0 0.7 0.0 0.0 1.6 1.1 0.4 0.0 1.1 0.0 0.2 3.2 2.2 0.2 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.4 0.0 0.0 0.0 3.7 2.9 0.0 0.0 9.6 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 31.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 1.6 9.1 1.9 2.3 0.1 0.2 0.2 0.3 0.0 0.0 2.1 0.0 0.0 0.0 11.1 33.5 0.1 0.2 0.0 0.0 4.4 0.1 0.0 2.5 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 66.6 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.7 0.1 0.0 0.0 164.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.8 8.4 0.3 0.1 1.0 39.7 10.6 0.0 0.0 0.0 0.9 0.0 0.0 3.8 0.7 0.1 0.0 11.2 0.4 1.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1831.7;gallbladder: 1378.0;smooth muscle: 1416.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 774.5;Fibroblasts: 2148.2;Glandular and luminal cells: 592.2;Leydig cells: 991.9;Peritubular cells: 501.0;Smooth muscle cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3899.2;ASC TERT1: 4637.0;BJ: 3995.6;BJ hTERT+: 2901.2;fHDF/TERT166: 13615.1;HSkMC: 4058.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 133.7" "CAB032650, HPA059738" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 27000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA059738: AB_2684116" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" 514.8 52.4 6.8 266.2 9.3 2.0 314.5 7.1 17.4 1831.7 18.1 175.7 61.1 411.2 61.6 263.2 206.6 1378.0 275.4 6.0 6.8 40.8 27.4 229.5 91.6 8.7 6.7 297.2 57.1 32.5 33.5 624.6 7.9 196.2 141.8 1.6 60.2 232.3 51.6 424.6 103.2 1416.9 8.8 69.3 89.1 136.6 15.6 32.8 86.4 102.1 60.1 805.6 295.2 8.2 0.1 0.0 22.8 1488.5 3899.2 4637.0 1.3 3995.6 2901.2 642.6 850.5 0.0 2.8 0.3 2.7 13615.1 0.0 0.6 2.2 1.5 160.9 0.1 0.2 0.1 0.0 0.0 1018.6 1.1 0.5 4058.4 0.1 507.9 2.4 0.3 0.5 0.0 0.3 0.3 551.0 0.0 0.6 1.5 2.5 0.0 6.3 0.5 0.8 0.8 0.1 0.0 12.9 1.4 0.3 1.0 0.1 296.0 2.1 0.1 15.9 1626.3 0.8 1022.7 115.5 1.2 0.1 0.4 408.6 0.5 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 9.3 7.1 17.4 6.0 6.8 8.7 6.7 7.9 8.8 15.6 8.2 112.9 3.2 12.9 1.0 0.8 223.1 0.7 9.3 4.6 0.2 7.2 8.6 21.7 0.0 3.3 1.8 0.0 31.5 2.5 0.0 0.0 3.0 8.4 183.2 774.5 57.2 0.0 0.0 0.0 0.2 31.7 2148.2 26.5 592.2 10.1 16.4 258.8 1.9 116.9 0.0 0.1 0.0 0.0 1.0 394.5 45.1 991.9 16.7 238.3 97.4 2.6 3.2 0.0 0.0 0.2 5.2 0.0 501.0 4.5 1.0 0.0 0.5 0.8 0.4 302.4 249.9 770.7 9.9 4.5 6.2 187.4 70.7 30.6 214.8 0.0 0.8 COL20A1 KIAA1510 ENSG00000101203 "Collagen type XX alpha 1 chain" Q9P218 20 63293186-63334851 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.3;choroid plexus: 2.8;testis: 2.5" "Group enriched" "Detected in some" 11 "Oligodendrocyte precursor cells: 72.9;Spermatocytes: 21.8" "Cancer enriched" "Detected in single" 19 "glioma: 8.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA072382 Uncertain "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA "Cluster 65: Brain - Ion transport" "Cluster 68: Oligodendrocytes - Mixed function" "Endoplasmic reticulum" "HPA072382: " "unprognostic (6.34e-4)" "unprognostic (2.52e-1)" "unprognostic (1.29e-2)" "unprognostic (1.69e-1)" "unprognostic (2.01e-1)" "unprognostic (5.82e-2)" "unprognostic (1.29e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "unprognostic (1.70e-2)" "unprognostic (1.71e-1)" "unprognostic (2.89e-1)" "unprognostic (8.41e-7)" "unprognostic (7.85e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-2)" "unprognostic (1.16e-1)" 0.0 0.2 3.9 0.0 4.0 0.0 0.0 3.0 8.3 0.5 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.9 2.8 0.1 0.0 0.0 0.0 3.7 3.3 0.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 3.3 0.7 0.0 2.5 3.4 0.0 0.0 0.3 0.0 0.0 0.1 5.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 3.0 8.3 3.9 2.8 3.7 3.3 3.6 3.3 3.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 3.3 0.4 0.0 0.0 0.0 0.0 2.7 0.3 0.0 0.0 0.0 0.0 0.4 0.0 72.9 0.3 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.2 0.1 21.8 4.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 COL21A1 ENSG00000124749 "Collagen type XXI alpha 1 chain" Q96P44 6 56056590-56394094 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.1;placenta: 28.3" "Cell type enhanced" "Detected in many" "Astrocytes: 66.6;Cardiomyocytes: 36.9;Extravillous trophoblasts: 75.3;Inhibitory neurons: 63.3;Respiratory ciliated cells: 51.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 23.4;BEWO: 7.6;HSkMC: 24.0;SuSa: 11.1" "Low region specificity" "Detected in all" HPA031212 Supported Cytosol "Secreted to extracellular matrix" NA NA 290000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA031212: AB_10599941" "unprognostic (1.69e-1)" "unprognostic (4.53e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-1)" "unprognostic (1.21e-1)" "unprognostic (9.32e-3)" "unprognostic (6.84e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-3)" "unprognostic (2.17e-1)" "unprognostic (5.29e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-3)" "unprognostic (3.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-3)" 2.6 1.4 2.6 0.6 3.2 0.0 1.4 3.3 1.9 24.1 11.4 7.8 0.5 12.4 2.8 2.4 7.4 3.8 4.2 2.4 5.6 1.1 1.2 7.6 0.5 2.7 6.3 3.7 1.9 0.6 1.9 28.3 3.1 3.5 2.0 0.0 5.0 10.7 1.3 6.6 1.3 7.9 1.5 0.5 2.7 2.7 4.0 0.7 1.0 6.6 0.5 6.1 6.0 2.7 0.0 3.4 0.2 0.0 1.3 23.4 7.6 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.2 0.1 0.0 24.0 0.9 0.0 0.3 0.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.2 3.3 1.9 2.4 5.6 2.7 6.3 3.1 1.5 4.0 2.7 6.4 0.0 1.5 66.6 0.0 5.9 2.2 2.8 2.2 0.0 0.3 0.4 36.9 0.0 8.2 0.0 0.0 27.5 0.1 0.0 0.0 0.0 7.4 24.8 10.6 6.6 0.0 0.0 16.0 0.0 75.3 28.2 0.5 1.2 0.0 0.2 2.9 0.0 6.1 0.0 63.3 0.0 16.2 0.3 3.0 1.7 15.2 0.3 5.4 0.0 0.0 0.0 0.0 3.5 1.6 0.0 0.0 12.4 0.0 0.1 0.1 0.1 51.3 0.0 0.0 7.3 15.0 1.2 2.5 1.0 4.1 23.3 0.4 2.1 0.2 1.3 COL22A1 ENSG00000169436 "Collagen type XXII alpha 1 chain" Q8NFW1 8 138588235-138914041 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pituitary gland: 44.0" "Cell type enhanced" "Detected in some" "Early spermatids: 39.6;Excitatory neurons: 13.0;Late spermatids: 33.7;Muller glia cells: 25.5" "Cancer enhanced" "Detected in many" "testis cancer: 9.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 29.5;RT4: 12.2;SCLC-21H: 8.1;U-2 OS: 6.8" "Low region specificity" "Detected in many" HPA024830 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA024830: AB_1847102" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (2.88e-2)" "unprognostic (4.19e-6)" "prognostic unfavorable (4.15e-4)" "unprognostic (1.05e-2)" "unprognostic (5.57e-3)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.01e-1)" "unprognostic (9.24e-2)" "unprognostic (5.74e-2)" "unprognostic (3.62e-2)" "unprognostic (3.66e-15)" "unprognostic (2.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (1.09e-1)" 0.1 7.6 0.6 0.6 1.0 0.0 0.0 2.9 0.5 0.8 0.4 1.0 0.3 1.9 0.2 0.1 0.4 0.3 0.2 0.3 1.4 1.9 0.0 0.0 0.5 2.9 1.2 0.2 0.1 1.4 44.0 0.0 0.6 3.0 0.1 5.2 0.9 2.4 0.7 0.0 0.4 1.6 4.3 0.2 2.2 1.1 2.0 2.1 0.2 1.1 1.2 0.9 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 12.2 8.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 2.9 0.5 0.3 1.4 2.9 1.2 0.6 4.3 2.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 3.7 2.5 0.0 0.3 0.2 0.3 1.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 39.6 0.1 0.2 0.8 0.0 0.0 13.0 0.2 0.0 0.2 0.0 0.6 0.0 0.6 0.0 0.0 5.9 0.0 0.8 0.0 8.2 0.0 0.0 33.7 0.3 0.3 0.0 1.0 0.6 25.5 0.0 0.5 0.3 3.0 0.0 0.0 0.0 4.8 0.0 0.1 0.2 1.6 0.0 0.1 0.3 2.1 1.7 0.0 0.0 0.0 0.0 0.0 0.1 1.9 COL24A1 ENSG00000171502 "Collagen type XXIV alpha 1 chain" Q17RW2 1 85729233-86156943 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.0" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 167.1" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "cerebral cortex: 9.0;hippocampal formation: 8.2" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 2.7" "Lineage enriched" "Detected in single" 9 "dendritic cells: 2.7" "Cell line enhanced" "Detected in some" "ASC diff: 2.1;Karpas-707: 3.7;NTERA-2: 1.9;RH-30: 2.7;SuSa: 2.8;U-266/70: 6.9" "Secreted to extracellular matrix" NA NA 52000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (3.00e-1)" "unprognostic (6.19e-2)" "unprognostic (2.21e-2)" "unprognostic (6.76e-3)" "unprognostic (1.82e-3)" "unprognostic (2.45e-2)" "unprognostic (2.44e-5)" "unprognostic (1.37e-1)" "unprognostic (4.08e-2)" "unprognostic (6.59e-2)" "unprognostic (3.89e-2)" "unprognostic (1.46e-1)" "unprognostic (3.48e-6)" "unprognostic (2.79e-5)" "unprognostic (5.07e-1)" "unprognostic (1.19e-1)" "unprognostic (9.90e-2)" 0.7 0.0 0.9 0.8 2.7 0.9 0.3 0.0 9.0 6.8 0.0 6.7 1.5 1.2 0.8 0.7 0.1 1.5 1.9 8.2 0.9 0.8 0.0 0.7 0.3 0.0 0.0 2.4 0.0 0.0 1.2 0.1 0.0 1.1 0.8 5.5 0.4 1.4 0.5 0.6 1.7 0.9 0.1 0.3 1.7 0.8 0.0 0.2 0.4 1.7 0.3 5.0 2.9 1.8 0.0 0.0 0.9 0.0 2.1 0.3 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.9 0.0 0.5 0.0 0.7 0.0 0.1 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.5 0.0 0.0 0.1 1.9 0.0 0.0 0.0 2.7 0.3 0.3 0.7 0.0 0.0 0.0 0.1 0.3 2.8 0.0 0.6 0.0 1.2 0.1 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.0 0.0 0.9 2.7 0.0 9.0 8.2 0.9 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.6 6.8 1.1 0.4 0.0 0.2 0.0 1.9 0.5 0.0 2.1 0.0 0.5 5.5 0.0 0.0 11.1 0.0 0.0 0.0 0.1 0.2 3.7 0.4 0.0 2.5 167.1 0.0 0.0 2.8 0.0 0.1 1.3 0.5 0.0 0.0 2.4 0.0 12.9 0.0 0.0 0.0 0.4 0.2 0.9 0.9 10.6 7.5 0.0 40.4 0.0 11.1 6.5 0.0 0.0 0.7 3.3 0.0 0.0 0.1 2.4 1.7 0.0 0.5 1.3 1.0 0.9 0.0 0.1 0.0 0.3 2.8 0.0 0.0 COL25A1 ENSG00000188517 "Collagen type XXV alpha 1 chain" Q9BXS0 4 108808725-109302752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.0;retina: 24.7;testis: 19.1" "Cell type enhanced" "Detected in some" "Early spermatids: 107.1;Inhibitory neurons: 275.3;Late spermatids: 39.2;Rod photoreceptor cells: 71.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HeLa: 47.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029107 Approved "Endoplasmic reticulum,Vesicles,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "Endoplasmic reticulum" "HPA029107: AB_10600802" "unprognostic (1.77e-1)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "unprognostic (8.87e-5)" "unprognostic (2.43e-2)" "unprognostic (3.20e-1)" "unprognostic (7.62e-3)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (3.53e-1)" "unprognostic (1.50e-2)" "unprognostic (1.17e-1)" "unprognostic (5.30e-3)" "unprognostic (2.82e-3)" "unprognostic (9.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" 6.1 0.5 13.4 0.1 10.3 0.0 2.8 0.0 30.0 1.1 0.3 0.4 2.9 0.6 1.6 0.4 0.9 2.2 0.5 17.8 13.7 1.9 2.2 0.2 0.1 6.5 9.4 1.0 0.2 1.3 7.0 0.3 1.0 0.5 0.3 24.7 4.9 0.5 1.0 0.7 2.5 0.8 6.9 0.8 0.3 19.1 8.9 0.5 2.8 0.3 0.1 0.7 1.0 1.7 0.0 0.0 5.3 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 2.7 0.0 0.1 0.0 3.2 5.9 47.6 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.2 0.0 0.1 1.2 0.2 5.6 0.0 0.8 0.0 1.6 0.0 0.1 0.0 2.6 0.0 0.0 0.0 1.1 0.0 0.0 0.2 1.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 10.3 0.0 30.0 17.8 13.7 6.5 9.4 1.0 6.9 8.9 1.7 8.2 0.0 0.0 12.4 0.1 0.0 0.1 0.0 2.2 2.1 0.4 0.6 1.0 0.0 0.6 1.8 4.2 0.0 0.0 0.0 0.0 0.0 107.1 6.5 2.0 1.6 0.0 0.0 20.5 0.0 0.0 0.7 0.0 18.9 0.0 0.5 0.7 0.0 0.0 1.7 275.3 0.0 0.0 0.0 0.4 39.2 0.6 0.2 0.0 10.3 0.0 2.8 0.0 16.6 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 71.5 0.0 4.7 24.6 7.8 1.6 0.0 0.1 0.0 0.1 0.3 0.0 0.0 COL26A1 "EMI6, EMID2, Emu2" ENSG00000160963 "Collagen type XXVI alpha 1 chain" Q96A83 7 101362875-101559024 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;liver: 5.5" "Group enriched" "Detected in some" 7 "Excitatory neurons: 68.4;Inhibitory neurons: 18.5" "Group enriched" "Detected in many" 6 "endometrial cancer: 12.6;ovarian cancer: 5.7;prostate cancer: 4.6;testis cancer: 14.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 45 "plasmacytoid DC: 9.2" "Lineage enriched" "Detected in single" 45 "dendritic cells: 9.2" "Cell line enhanced" "Detected in some" "AF22: 30.0;BEWO: 23.9;HAP1: 10.7;NTERA-2: 25.4;SuSa: 19.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA027059 Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA027059: AB_1848142" "unprognostic (5.94e-3)" "unprognostic (2.16e-2)" "unprognostic (2.19e-2)" "unprognostic (4.67e-2)" "unprognostic (1.66e-1)" "unprognostic (3.35e-1)" "prognostic favorable (2.32e-5)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.26e-3)" "unprognostic (1.78e-1)" "unprognostic (4.24e-3)" "unprognostic (3.60e-1)" "unprognostic (1.50e-1)" "unprognostic (7.48e-4)" "unprognostic (2.83e-3)" 0.1 4.4 5.2 0.1 7.4 0.2 0.1 0.2 12.8 0.2 0.2 0.0 0.0 0.3 0.1 0.0 0.3 0.1 0.0 9.8 1.2 4.9 5.5 0.4 0.5 1.1 0.9 0.4 2.2 3.9 0.9 0.3 0.9 2.2 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.4 0.2 0.3 1.0 2.0 1.2 0.1 0.0 0.1 0.2 0.1 4.2 0.0 0.8 30.0 1.9 0.0 0.0 23.9 0.0 0.0 0.0 0.0 1.3 0.0 0.1 4.7 0.0 0.1 0.0 10.7 0.0 0.0 1.0 1.3 0.0 0.0 7.9 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 25.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.6 0.0 0.0 0.2 19.2 0.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 5.2 7.4 0.2 12.8 9.8 1.2 1.1 0.9 0.9 0.4 2.0 4.2 0.0 0.0 0.0 3.3 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 5.5 0.0 0.3 0.0 0.0 0.0 0.2 1.5 0.1 1.7 0.1 0.0 0.0 68.4 0.6 0.4 0.5 0.0 0.2 0.0 1.0 0.0 3.6 0.1 0.0 18.5 0.0 0.0 0.0 0.0 3.5 0.0 0.5 0.0 5.6 0.0 0.0 0.0 3.5 2.1 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 2.0 0.0 0.0 0.4 0.0 0.9 0.0 0.4 COL27A1 "FLJ11895, KIAA1870, MGC11337" ENSG00000196739 "Collagen type XXVII alpha 1 chain" Q8IZC6 9 114155537-114312511 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 93.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 60.1;Extravillous trophoblasts: 75.5;Gastric mucus-secreting cells: 43.8;Hepatocytes: 43.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 29.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 54.8;Hep G2: 48.7" "Low region specificity" "Detected in some" "Region enriched" "Detected in all" 19 "cerebellum: 71.0" "HPA021884, HPA048471" Uncertain "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" "HPA021884: AB_2670857, HPA048471: AB_2680407" "unprognostic (4.45e-2)" "unprognostic (3.27e-1)" "unprognostic (1.32e-1)" "unprognostic (5.00e-2)" "prognostic unfavorable (7.11e-4)" "unprognostic (4.13e-1)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (6.25e-2)" "unprognostic (1.71e-1)" "unprognostic (1.09e-3)" "unprognostic (3.31e-1)" "unprognostic (3.41e-2)" "unprognostic (2.97e-2)" "unprognostic (9.48e-2)" "unprognostic (6.21e-3)" "unprognostic (3.50e-3)" 9.2 8.7 4.0 3.5 3.4 0.3 9.1 29.6 4.8 93.7 3.0 11.2 3.9 39.7 16.1 8.1 16.7 7.9 10.9 3.6 4.7 33.1 42.7 7.0 3.1 7.0 7.9 27.6 21.2 1.0 4.1 11.7 6.5 22.5 1.4 1.5 5.4 13.7 5.8 15.7 6.9 10.5 4.9 4.7 11.9 6.4 6.4 9.2 13.5 2.8 2.2 8.1 37.7 4.3 3.8 7.8 17.9 6.6 1.3 1.9 54.8 8.7 5.9 6.3 5.2 8.1 0.2 0.0 2.1 4.3 4.7 9.2 6.2 8.1 3.4 0.0 0.7 0.0 7.5 48.7 1.9 0.0 19.8 4.9 2.3 7.6 3.4 3.6 9.4 7.4 0.0 1.9 3.6 1.8 0.1 3.5 6.5 15.1 2.1 25.9 18.1 3.7 14.6 4.2 0.3 0.2 0.4 0.2 1.1 6.8 1.6 5.8 8.9 5.5 11.1 0.7 13.9 1.0 0.0 0.0 4.5 0.1 8.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 3.4 29.6 4.8 3.6 4.7 7.0 7.9 6.5 4.9 6.4 4.3 2.9 3.2 23.0 15.0 0.8 27.1 4.9 14.2 18.2 1.2 24.3 22.1 34.4 60.1 6.1 9.2 6.2 1.0 2.0 0.5 3.9 12.8 3.7 3.3 25.3 7.1 4.8 0.0 11.0 5.1 75.5 15.0 43.8 11.5 0.0 6.9 3.6 43.6 6.5 1.7 4.6 1.8 0.0 1.0 4.1 1.6 19.3 0.8 23.2 8.4 0.1 5.6 0.0 25.6 0.8 4.7 2.5 4.5 0.4 10.6 0.3 9.8 0.6 1.4 26.3 4.9 40.1 0.5 2.0 5.8 22.4 2.3 1.4 23.8 2.4 3.2 COL28A1 ENSG00000215018 "Collagen type XXVIII alpha 1 chain" Q2UY09 7 7356203-7535873 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 18.2" "Cell type enhanced" "Detected in many" "Astrocytes: 39.5;Cone photoreceptor cells: 18.8;Endometrial ciliated cells: 21.1;Excitatory neurons: 23.4;Inhibitory neurons: 22.6;Oligodendrocyte precursor cells: 12.5;Respiratory ciliated cells: 16.3" "Cancer enhanced" "Detected in many" "glioma: 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 2.3;U-266/70: 9.8;U-266/84: 2.8;WM-115: 4.9" "Region enriched" "Detected in single" 8 "olfactory bulb: 3.6" "Region enriched" "Detected in some" 31 "spinal cord: 33.5" "HPA043844, HPA060468" Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 51: Non-specific - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "HPA043844: AB_2732508, HPA060468: AB_2684288" "unprognostic (6.28e-2)" "unprognostic (2.90e-2)" "unprognostic (1.28e-1)" "unprognostic (8.71e-3)" "unprognostic (1.89e-2)" "unprognostic (5.63e-3)" "unprognostic (2.61e-2)" "unprognostic (7.58e-2)" "unprognostic (2.72e-2)" "unprognostic (7.69e-2)" "unprognostic (3.90e-3)" "unprognostic (2.33e-2)" "unprognostic (3.45e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (2.48e-3)" "unprognostic (3.09e-2)" 1.0 3.2 0.8 1.6 1.0 0.3 2.8 1.9 2.7 3.3 1.4 11.7 1.2 2.2 14.1 2.1 4.9 1.5 3.7 1.1 0.9 6.3 0.7 1.2 0.2 0.9 3.6 1.2 5.8 0.2 11.2 0.5 1.4 3.9 4.1 6.7 18.2 5.1 5.9 2.1 3.4 1.7 0.2 0.4 6.5 3.7 1.1 0.2 1.2 3.2 0.1 2.9 4.5 1.5 1.5 0.0 0.0 0.0 0.1 0.7 0.2 0.1 0.4 0.0 0.0 1.1 0.4 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.2 0.2 0.1 0.0 0.2 1.4 0.1 0.2 0.0 0.7 0.9 0.3 0.0 0.1 0.0 2.3 0.0 0.1 0.0 0.1 0.7 0.0 0.3 0.1 0.5 0.7 0.1 0.5 1.3 0.0 9.8 2.8 0.0 0.2 0.6 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.8 1.0 1.9 2.7 1.1 0.9 0.9 3.6 1.4 0.2 1.1 1.5 0.4 0.0 4.1 39.5 0.0 0.3 0.1 0.2 0.0 5.3 1.6 1.5 0.9 0.0 3.3 3.7 18.8 0.3 0.1 0.8 0.0 0.1 2.0 21.1 0.5 0.1 0.0 0.0 23.4 0.2 0.0 3.1 0.0 3.9 1.3 0.5 1.8 0.0 0.1 5.0 22.6 0.5 0.0 0.3 0.3 1.1 0.9 0.1 0.0 7.5 0.0 2.2 0.0 12.5 9.1 0.4 5.4 0.7 0.0 0.1 0.2 0.5 16.3 5.4 0.0 1.8 0.2 0.9 1.0 0.1 0.1 0.3 0.1 0.2 0.3 0.1 COL2A1 "AOM, SEDC, STL1" ENSG00000139219 "Collagen type II alpha 1 chain" P02458 12 47972967-48004554 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, FDA approved drug targets, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 19.1;pituitary gland: 9.2;retina: 5.6;stomach 1: 12.5" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Enteroendocrine cells: 43.9;Late spermatids: 9.7;Muller glia cells: 22.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 156.3;HAP1: 98.9;HEK 293: 36.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002214, HPA055753" Approved Approved Nucleoplasm "Secreted to extracellular matrix" No NA 1400000 "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Nucleoplasm "CAB002214: AB_563666, HPA055753: AB_2682908" "unprognostic (7.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.58e-1)" "unprognostic (3.44e-1)" "unprognostic (2.88e-2)" "unprognostic (3.08e-2)" "unprognostic (8.63e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (3.12e-2)" "unprognostic (1.31e-4)" "unprognostic (2.64e-1)" "unprognostic (3.44e-3)" "unprognostic (1.89e-1)" "unprognostic (2.93e-1)" "unprognostic (2.07e-1)" "unprognostic (1.02e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.2 0.1 0.0 0.2 0.0 0.2 19.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.2 0.2 1.3 0.0 0.0 9.2 0.3 0.3 1.0 0.3 5.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.5 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 156.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.7 0.0 0.0 0.0 98.9 0.0 0.0 0.0 36.3 0.2 0.0 5.7 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.0 0.0 0.1 0.0 2.9 0.0 0.0 0.1 2.2 0.1 0.0 0.0 0.0 11.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.3 0.2 0.2 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.0 0.6 5.7 0.9 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 15.4 0.3 0.1 0.2 43.9 0.0 0.2 0.0 0.3 0.5 0.0 0.2 0.0 1.3 0.0 0.0 0.2 0.0 0.1 0.6 0.0 0.0 0.0 9.7 0.9 0.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.2 0.0 1.7 0.0 0.9 0.3 0.6 1.1 0.0 0.0 0.8 0.1 0.1 1.7 0.1 COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2369.0;gallbladder: 2092.8;placenta: 1981.7;smooth muscle: 2140.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2812.0;Fibroblasts: 1764.2;Smooth muscle cells: 643.0;Theca cells: 466.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 15.0;thalamus: 10.9;white matter: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 1362.4;ASC diff: 2465.0;ASC TERT1: 4252.6;fHDF/TERT166: 1815.7;HHSteC: 1690.0;HSkMC: 3189.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 61.1" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 32000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" 763.6 48.9 1.1 575.5 2.3 1.1 340.0 1.4 15.0 2369.0 11.5 275.9 84.5 768.9 60.9 298.5 177.6 2092.8 234.6 1.3 1.4 42.9 97.4 187.0 119.0 1.8 2.0 146.9 45.2 37.0 13.6 1981.7 2.2 147.5 334.7 0.0 65.6 276.9 67.1 329.8 152.5 2140.7 1.9 134.7 156.9 63.5 10.9 40.9 71.8 71.8 73.1 1097.6 273.8 4.6 0.0 0.2 1362.4 53.0 2465.0 4252.6 0.9 558.6 495.3 239.4 212.8 8.1 0.0 0.6 0.3 1815.7 0.1 0.8 1.1 1.0 26.4 0.0 0.9 0.7 228.9 0.2 1690.0 2.0 0.6 3189.5 0.0 291.5 46.9 1.0 12.5 0.0 0.4 0.0 146.4 0.0 0.2 1.4 2.6 0.1 1.7 0.3 38.5 0.5 0.0 7.2 1.3 21.1 14.5 0.4 0.0 954.8 0.1 0.0 0.7 2.3 28.0 117.3 0.5 2.8 1.3 0.4 0.5 1.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.3 1.4 15.0 1.3 1.4 1.8 2.0 2.2 1.9 10.9 4.6 111.8 3.2 13.7 0.0 0.6 171.6 0.4 1.9 3.4 0.0 7.7 9.9 11.1 0.0 1.3 0.0 0.0 57.9 1.6 0.0 0.0 2.4 29.0 75.4 2812.0 68.4 6.0 0.0 0.0 0.0 58.1 1764.2 4.1 60.7 6.3 9.7 235.2 0.9 91.1 0.0 0.2 0.0 0.0 0.6 275.3 20.8 323.1 17.5 172.5 20.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 235.9 1.5 0.6 0.0 0.2 1.6 0.0 453.6 224.3 643.0 0.9 1.5 2.2 155.7 126.3 29.1 466.8 0.0 0.4 COL4A1 ENSG00000187498 "Collagen type IV alpha 1 chain" P02462 13 110148963-110307157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 900.3" "Cell type enhanced" "Detected in many" "Adipocytes: 401.4;Endometrial stromal cells: 312.2;Endothelial cells: 385.9;Extravillous trophoblasts: 672.4;Sertoli cells: 506.2;Smooth muscle cells: 415.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.4" "Cell line enhanced" "Detected in many" "ASC diff: 501.6;EFO-21: 915.3;TIME: 331.3" "Low region specificity" "Detected in all" CAB001695 Approved "Secreted to extracellular matrix" NA NA 75000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB001695: " "unprognostic (3.82e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (2.27e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-3)" "unprognostic (1.06e-2)" "unprognostic (9.79e-2)" "unprognostic (1.73e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.47e-3)" "unprognostic (1.72e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-2)" 348.4 33.6 10.8 135.9 5.2 0.4 130.4 3.7 9.0 65.7 8.9 108.5 24.8 105.3 14.8 40.8 64.1 116.8 81.9 12.6 5.2 53.4 22.1 137.0 27.7 9.1 7.0 27.0 36.0 36.3 12.8 900.3 7.5 53.6 30.4 1.8 19.0 85.6 40.1 25.2 43.4 312.7 6.8 76.3 50.1 10.7 13.7 10.7 54.7 47.0 11.1 120.8 38.2 6.9 40.0 15.2 195.9 0.3 501.6 148.9 274.9 246.2 59.5 134.0 65.3 4.2 0.8 0.1 915.3 46.2 59.7 26.8 0.0 55.8 30.3 1.3 29.5 0.2 28.2 0.0 142.8 0.0 0.4 49.7 8.9 132.8 59.4 212.8 207.7 0.1 0.3 0.2 31.1 0.1 0.1 0.8 28.1 0.2 3.6 0.4 58.6 0.1 278.8 0.0 1.4 29.8 0.1 0.4 61.0 192.4 0.1 13.9 331.3 39.9 121.4 1.0 97.4 0.3 1.8 3.9 0.4 0.7 297.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 10.8 5.2 3.7 9.0 12.6 5.2 9.1 7.0 7.5 6.8 13.7 6.9 401.4 41.7 8.9 5.2 1.9 14.0 9.7 8.5 2.8 1.0 3.5 16.5 41.1 10.0 0.9 23.9 0.0 49.7 0.5 0.1 1.9 22.6 0.7 19.8 312.2 385.9 0.0 0.0 10.5 0.2 672.4 211.8 1.5 48.7 1.3 215.8 134.6 1.3 27.7 0.0 18.9 0.5 0.0 4.4 19.2 2.8 38.5 4.2 30.2 36.5 0.6 2.5 0.0 1.0 0.9 0.6 0.1 109.4 0.5 6.2 0.5 26.7 2.8 0.4 506.2 142.8 415.1 1.2 5.0 0.8 15.2 45.0 4.2 45.9 0.6 2.2 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COL4A3 ENSG00000169031 "Collagen type IV alpha 3 chain" Q01955 2 227164624-227314792 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 52.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 169.9;Bipolar cells: 62.1;Cone photoreceptor cells: 398.2;Muller glia cells: 143.1;Oligodendrocyte precursor cells: 84.9" "Group enriched" "Detected in some" 6 "lung cancer: 1.7;renal cancer: 3.0;thyroid cancer: 5.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Lineage enriched" "Detected in single" 7 "B-cells: 1.0" "Cell line enhanced" "Detected in some" "HeLa: 18.8;hTERT-RPE1: 14.5;Karpas-707: 9.9;RPTEC TERT1: 11.0;U-266/70: 9.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042064 Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA042064: AB_10794410" "unprognostic (4.81e-2)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (9.28e-6)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (1.84e-2)" "unprognostic (7.07e-3)" "unprognostic (2.30e-1)" "unprognostic (9.09e-3)" "unprognostic (9.30e-2)" "unprognostic (3.02e-2)" "prognostic favorable (2.51e-7)" "unprognostic (1.78e-1)" "unprognostic (3.10e-2)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" 0.6 11.5 1.9 2.1 1.8 0.3 1.0 1.5 1.7 0.4 21.5 0.8 0.7 1.2 16.3 1.0 2.1 3.2 8.9 1.4 2.0 30.5 0.6 15.0 2.9 3.3 3.1 3.9 5.0 0.2 16.2 0.2 2.7 6.0 1.0 52.9 1.2 9.9 22.2 0.5 6.7 0.8 1.6 7.2 1.8 1.7 6.3 0.4 20.5 15.2 5.6 1.4 1.2 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.8 0.0 0.0 0.3 1.1 0.1 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 1.2 0.0 9.9 0.0 0.4 0.0 0.1 1.4 0.0 0.0 0.1 0.0 3.2 11.0 2.3 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 9.0 3.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 1.5 1.7 1.4 2.0 3.3 3.1 2.7 1.6 6.3 2.2 0.5 169.9 31.7 3.9 14.0 0.1 0.1 0.1 0.6 62.1 0.1 0.9 2.6 1.5 9.3 42.3 398.2 0.1 0.1 0.0 0.0 0.1 0.7 0.1 0.2 2.4 0.0 0.0 5.5 1.0 0.0 4.6 0.5 0.3 1.3 22.8 0.4 0.2 0.0 1.7 14.1 0.0 0.0 0.0 0.3 0.3 8.4 0.3 1.8 13.1 0.0 143.1 0.0 84.9 3.6 1.0 0.0 12.0 8.0 0.1 0.0 1.9 0.1 11.9 13.1 11.7 3.6 0.4 0.0 0.3 0.3 0.0 1.2 0.1 0.0 0.0 COL4A4 CA44 ENSG00000081052 "Collagen type IV alpha 4 chain" P53420 2 227002714-227164453 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Collecting duct cells: 46.0;Cone photoreceptor cells: 56.3;Granulosa cells: 62.6;Muller glia cells: 78.6;Oligodendrocyte precursor cells: 55.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 4.1" "Lineage enriched" "Detected in single" 5 "B-cells: 4.1" "Cell line enhanced" "Detected in some" "HeLa: 34.3;hTERT-RPE1: 27.2;Karpas-707: 8.9;RPTEC TERT1: 14.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.31e-2)" "unprognostic (7.56e-2)" "unprognostic (6.65e-2)" "unprognostic (4.88e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (8.50e-3)" "unprognostic (5.14e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "prognostic favorable (2.30e-13)" "unprognostic (1.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (4.15e-2)" 1.0 6.9 1.3 2.1 1.1 0.1 0.7 0.9 0.9 0.5 14.2 0.9 0.9 2.0 7.2 1.1 2.1 4.4 9.2 1.0 1.3 14.0 1.6 8.3 2.8 3.1 2.2 2.0 5.5 0.6 10.2 0.3 2.6 4.5 0.8 8.4 0.7 8.3 6.9 0.3 2.4 1.6 1.5 1.9 1.2 1.3 4.4 0.9 9.9 5.7 4.5 2.9 0.9 1.3 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.3 0.2 0.1 0.6 0.0 0.7 0.0 1.7 0.0 0.7 0.1 3.1 1.1 0.2 0.0 3.4 0.0 34.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 27.2 0.0 1.1 0.0 8.9 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 14.5 5.6 0.8 0.0 2.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 2.7 0.0 0.3 6.7 5.3 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.3 0.0 0.0 4.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 1.1 0.9 0.9 1.0 1.3 3.1 2.2 2.6 1.5 4.4 1.3 2.0 73.7 24.1 3.6 11.1 0.5 0.4 0.2 0.0 29.1 0.5 1.3 3.5 8.6 6.2 46.0 56.3 0.0 1.4 0.1 1.9 0.3 0.8 0.3 1.8 5.2 1.2 0.0 2.5 3.8 0.0 8.1 1.5 0.9 0.0 62.6 2.5 0.7 0.1 0.0 10.4 0.1 2.0 0.3 1.5 4.3 25.1 0.8 0.0 12.2 0.0 78.6 0.0 55.3 3.4 4.1 0.1 27.1 14.9 0.2 0.0 3.6 0.0 8.5 0.0 16.8 8.6 0.1 0.6 0.2 0.0 0.0 1.4 0.9 0.3 0.1 COL4A5 "ASLN, ATS" ENSG00000188153 "Collagen type IV alpha 5 chain" P29400 X 108439838-108697545 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.9" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 713.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 87.7;HHSteC: 95.0;HUVEC TERT2: 92.8;TIME: 88.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077177 Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "HPA077177: " "unprognostic (2.58e-2)" "unprognostic (2.57e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-2)" "unprognostic (7.27e-2)" "unprognostic (2.70e-1)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.41e-5)" "unprognostic (2.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (1.06e-1)" 7.4 5.6 25.2 2.3 57.4 0.0 8.1 38.2 40.8 38.1 20.0 5.8 3.8 59.2 25.4 9.6 37.5 18.2 10.9 27.0 33.7 16.9 2.4 8.5 1.2 47.7 43.1 23.0 3.8 16.8 19.7 14.5 47.4 37.0 5.6 6.1 7.4 32.9 7.6 26.4 6.3 47.2 36.4 5.5 34.5 6.0 45.3 2.7 10.5 4.4 1.0 47.6 22.7 102.9 4.5 26.7 47.2 14.9 18.0 10.6 0.3 2.8 11.7 14.2 23.2 24.0 1.9 4.2 0.0 2.0 8.6 21.7 13.2 45.2 17.8 6.7 11.7 3.4 87.7 2.9 95.0 0.0 13.5 49.2 53.6 17.4 37.2 45.2 92.8 0.0 0.2 0.1 13.9 2.0 0.1 0.5 14.0 0.0 16.0 0.1 0.0 0.2 35.9 26.7 0.0 0.0 70.2 2.2 6.0 65.6 12.9 0.0 88.8 9.5 2.8 6.4 4.0 1.9 0.0 0.0 8.2 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 57.4 38.2 40.8 27.0 33.7 47.7 43.1 47.4 36.4 45.3 102.9 1.0 6.4 7.3 72.5 0.0 26.9 29.7 29.4 17.1 0.5 14.8 14.7 10.0 2.8 14.2 20.2 0.0 0.7 0.0 0.0 0.0 0.4 0.1 7.4 45.4 4.6 0.0 0.0 1.1 0.9 0.4 12.3 3.1 5.7 1.3 2.0 4.2 0.5 0.4 0.0 1.5 0.2 6.1 0.3 2.1 1.7 20.2 0.6 1.8 20.6 0.0 11.1 0.0 3.5 713.9 0.4 0.0 36.9 0.0 18.1 0.0 0.1 8.2 0.6 6.6 2.4 18.3 0.4 0.9 4.2 15.9 0.7 1.1 21.5 0.1 24.7 COL4A6 ENSG00000197565 "Collagen type IV alpha 6 chain" Q14031 X 108155607-108439497 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 32.6;urinary bladder: 40.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 24.5;Basal respiratory cells: 16.0;Cardiomyocytes: 13.1;Prostatic glandular cells: 12.1;Urothelial cells: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 46.0;HeLa: 40.1;HHSteC: 59.2;hTERT-HME1: 44.1;HUVEC TERT2: 41.7;TIME: 94.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA065393 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Endoplasmic reticulum" "HPA065393: AB_2685483" "unprognostic (8.47e-3)" "unprognostic (4.50e-3)" "unprognostic (9.75e-3)" "unprognostic (9.80e-3)" "unprognostic (1.18e-1)" "unprognostic (5.99e-2)" "unprognostic (1.78e-2)" "unprognostic (3.78e-2)" "unprognostic (1.72e-1)" "unprognostic (9.84e-2)" "unprognostic (1.40e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.32e-2)" "unprognostic (2.06e-1)" "unprognostic (8.54e-3)" "unprognostic (3.51e-1)" 3.0 0.5 0.3 0.4 0.3 0.0 2.0 0.2 0.2 12.6 1.3 1.9 1.4 32.6 17.0 5.5 14.9 13.3 5.4 0.3 0.7 4.2 0.1 1.0 0.1 0.9 1.7 9.3 0.1 5.5 7.2 3.2 1.0 12.5 2.1 1.2 1.4 21.5 1.4 6.5 1.5 24.5 0.4 1.4 13.3 1.2 0.3 0.9 0.7 1.2 0.1 40.7 9.2 0.6 0.1 31.1 9.9 0.0 24.2 1.7 0.0 0.0 1.8 0.3 0.2 17.9 0.0 0.0 0.0 0.0 3.9 5.8 10.3 46.0 0.8 0.4 8.8 0.8 40.1 0.3 59.2 0.0 0.0 2.6 27.8 6.5 44.1 0.1 41.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 14.0 0.0 3.8 0.0 0.0 0.0 1.9 3.4 0.0 0.0 2.4 0.0 0.0 18.2 0.9 0.0 94.2 0.0 0.1 5.5 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.2 0.3 0.7 0.9 1.7 1.0 0.4 0.3 0.6 0.1 0.0 0.0 6.2 0.0 6.4 24.5 16.0 3.4 0.2 2.3 6.1 13.1 0.0 2.6 1.8 0.0 0.1 0.0 0.0 1.9 0.0 2.1 0.7 6.0 0.4 0.0 0.0 0.4 0.0 0.0 6.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 2.0 0.0 0.3 0.3 4.1 0.0 0.0 8.4 0.0 5.5 0.0 0.0 0.6 0.1 0.0 9.1 0.0 12.1 0.0 0.0 2.2 0.4 0.0 0.4 7.2 0.2 0.2 0.1 3.7 0.0 0.1 0.8 0.0 15.2 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 186.0;Excitatory neurons: 185.2;Fibroblasts: 145.7;Skeletal myocytes: 76.4;Smooth muscle cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 447.8;BJ hTERT+ SV40 Large T+ RasG12V: 382.4;fHDF/TERT166: 430.3;HSkMC: 340.2;SuSa: 373.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" 61.0 4.8 2.3 42.5 5.7 0.2 25.7 0.0 15.6 83.4 3.1 48.7 10.0 43.4 32.7 23.6 21.2 81.9 19.5 17.6 0.8 6.3 12.4 26.1 9.3 2.0 17.4 25.2 7.1 7.5 7.3 111.5 3.8 14.8 25.4 1.6 7.4 12.8 7.8 12.9 22.8 98.3 1.9 10.0 21.5 6.8 1.0 4.7 9.8 26.8 10.3 57.3 29.7 2.5 0.4 93.5 143.9 67.5 212.0 285.3 0.8 213.7 242.3 447.8 382.4 63.2 0.7 0.2 2.2 430.3 23.2 1.6 4.1 2.3 153.3 0.9 1.3 1.0 2.1 0.6 282.6 0.6 0.4 340.2 7.8 129.8 45.3 92.2 108.5 0.9 0.5 0.4 109.1 2.4 0.3 0.3 20.9 0.9 124.3 0.5 33.9 0.4 0.5 24.9 2.0 1.4 5.2 2.5 5.2 373.0 2.1 0.2 91.6 212.8 22.9 52.6 44.6 0.8 0.4 0.6 32.2 0.1 235.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 15.6 17.6 0.8 2.0 17.4 3.8 1.9 1.0 2.5 36.7 0.0 1.5 29.7 0.3 26.1 0.2 7.2 6.2 1.3 1.6 3.7 2.8 0.0 0.7 1.8 0.0 4.6 0.2 0.5 1.9 0.6 0.7 22.4 186.0 9.1 38.7 0.0 185.2 0.7 3.9 145.7 0.5 5.1 0.0 4.2 25.7 7.4 6.6 0.0 23.8 0.2 4.1 0.3 27.4 1.7 48.7 1.4 21.4 25.3 0.6 0.7 0.0 21.6 10.9 1.1 0.1 19.5 0.4 0.3 0.1 1.0 1.9 0.8 46.0 76.4 116.0 3.9 1.8 2.0 18.8 6.2 2.8 27.4 0.0 0.4 COL5A3 ENSG00000080573 "Collagen type V alpha 3 chain" P25940 19 9959561-10010504 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Astrocytes: 510.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 38.9;BJ: 23.6;BJ hTERT+: 26.2;BJ hTERT+ SV40 Large T+: 14.4;HSkMC: 28.2;WM-115: 26.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA041695, HPA048256" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 330000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA041695: , HPA048256: AB_2680330" "unprognostic (1.17e-1)" "unprognostic (1.35e-2)" "unprognostic (4.63e-2)" "unprognostic (3.24e-2)" "unprognostic (6.84e-3)" "unprognostic (3.01e-1)" "unprognostic (7.47e-2)" "unprognostic (1.79e-2)" "unprognostic (2.36e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.17e-8)" "unprognostic (3.25e-2)" "unprognostic (7.31e-3)" "unprognostic (6.00e-2)" "prognostic unfavorable (6.87e-5)" 47.4 5.0 33.2 9.9 33.2 0.1 32.3 30.6 45.9 44.9 43.6 19.3 3.7 27.3 1.9 9.0 22.8 4.1 33.5 33.3 26.4 7.9 13.4 14.2 3.2 35.2 30.2 6.3 5.2 3.0 3.5 32.8 32.3 16.6 2.0 21.1 7.3 8.9 15.3 21.7 11.7 10.3 31.0 1.7 9.9 4.7 30.2 4.5 12.7 6.0 3.9 12.6 26.4 28.4 0.0 0.0 0.5 0.0 12.4 38.9 0.0 23.6 26.2 14.4 5.7 0.0 0.0 0.0 0.2 4.4 0.3 2.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 28.2 0.6 5.2 5.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.1 0.0 0.0 0.0 11.6 5.5 0.5 0.0 0.0 0.0 0.0 1.5 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 33.2 30.6 45.9 33.3 26.4 35.2 30.2 32.3 31.0 30.2 28.4 13.7 0.0 0.0 510.3 0.0 4.2 0.1 0.2 2.2 65.1 0.3 0.9 6.4 0.0 0.1 0.0 6.2 0.1 0.3 1.3 0.0 0.2 6.9 0.4 12.0 8.1 0.0 0.0 15.6 0.0 0.2 17.5 0.5 0.4 0.0 0.0 3.9 22.9 0.6 3.3 3.4 0.0 0.0 0.0 3.2 2.1 17.4 0.4 14.2 36.5 0.1 2.6 0.0 73.9 2.5 0.3 0.1 8.2 0.0 0.3 0.2 0.1 0.9 28.3 92.1 8.5 58.0 0.3 0.3 3.2 7.1 0.1 1.9 0.9 0.0 0.3 COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981769-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 796.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 578.3;Fibroblasts: 816.1;Leydig cells: 353.0;Peritubular cells: 251.3;Smooth muscle cells: 324.4;Theca cells: 246.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1157.2;ASC TERT1: 2331.5;BJ: 927.1;HHSteC: 1025.3;HSkMC: 1711.4;U-138 MG: 1297.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 46.8" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" NA NA 250000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" 285.9 50.1 15.7 153.3 9.0 0.7 173.9 33.9 20.4 499.3 32.1 796.8 73.3 556.3 24.6 91.1 411.5 194.4 155.6 10.3 14.9 66.1 48.3 140.3 37.5 23.1 18.4 491.4 57.8 29.1 117.8 287.1 21.5 246.8 40.5 3.4 97.7 142.3 85.4 123.4 217.7 177.9 11.3 70.7 230.5 32.8 14.9 30.7 92.6 39.5 16.6 478.7 284.7 9.7 2.9 20.2 31.2 99.6 1157.2 2331.5 3.9 927.1 586.3 231.7 80.7 16.2 62.8 0.1 75.1 522.2 183.6 4.3 13.5 2.3 19.5 0.5 14.9 0.0 3.7 5.2 1025.3 0.3 2.2 1711.4 1.0 578.6 7.8 20.9 5.6 0.2 0.7 0.6 60.9 1.4 0.3 3.2 22.4 13.4 263.2 0.1 19.5 4.3 1.6 11.1 1.0 39.9 87.6 1.1 17.9 10.4 4.2 4.2 0.5 1297.6 86.7 362.7 358.1 0.6 0.4 0.4 464.1 6.9 116.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 9.0 33.9 20.4 10.3 14.9 23.1 18.4 21.5 11.3 14.9 9.7 74.6 0.0 5.8 26.1 2.5 122.2 11.0 1.5 18.2 18.9 9.2 35.9 42.7 5.7 4.4 9.2 0.0 11.6 2.3 0.6 3.9 23.2 4.6 20.9 578.3 50.6 1.8 0.0 27.1 3.3 18.6 816.1 6.1 16.1 1.3 48.7 101.0 13.4 22.4 15.2 8.2 0.3 0.0 3.3 134.7 18.6 353.0 7.8 147.7 40.3 2.0 18.7 0.0 30.7 2.4 6.1 2.6 251.3 3.5 6.3 2.1 10.3 1.0 4.3 184.1 152.3 324.4 2.6 6.2 5.5 89.9 20.8 13.7 246.5 1.4 3.8 COL6A2 ENSG00000142173 "Collagen type VI alpha 2 chain" P12110 21 46098112-46132848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 453.2;Fibroblasts: 1455.4;Leydig cells: 605.5;Peritubular cells: 472.1;Smooth muscle cells: 555.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 4.5;MAIT T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 1155.7;ASC TERT1: 2116.9;BJ: 1073.7;BJ hTERT+: 982.8;fHDF/TERT166: 775.0;HHSteC: 1129.2;HSkMC: 1524.4;U-138 MG: 1128.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 49.6" "HPA007029, HPA030920, HPA038799" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 8200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA007029: AB_1078549, HPA030920: AB_2673659, HPA038799: AB_2676214" "unprognostic (3.53e-1)" "unprognostic (3.76e-2)" "unprognostic (3.20e-2)" "unprognostic (4.87e-2)" "unprognostic (2.92e-2)" "unprognostic (1.38e-1)" "unprognostic (2.39e-1)" "unprognostic (5.28e-3)" "unprognostic (2.11e-2)" "unprognostic (1.68e-2)" "unprognostic (1.56e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.72e-14)" "unprognostic (2.13e-2)" "unprognostic (7.61e-2)" "unprognostic (2.31e-2)" "unprognostic (2.22e-3)" 732.4 96.2 10.1 219.9 10.8 4.5 455.0 8.7 14.4 873.3 21.6 1287.5 97.7 1001.7 36.5 178.8 675.1 283.8 484.3 10.0 14.9 96.5 97.6 394.2 55.7 14.0 19.4 723.6 78.6 24.0 112.2 335.3 11.2 569.9 60.2 0.9 156.2 274.6 123.4 390.6 402.2 275.4 9.8 175.1 441.6 77.0 11.7 35.6 201.3 67.2 25.6 918.6 595.9 12.3 9.4 12.5 34.8 31.2 1155.7 2116.9 10.0 1073.7 982.8 265.5 121.5 2.3 42.4 0.2 79.2 775.0 170.8 0.9 8.1 0.7 21.7 0.8 12.3 0.2 0.2 0.2 1129.2 0.5 4.8 1524.4 0.2 503.6 10.2 0.1 0.6 0.6 0.6 0.8 108.7 5.2 0.4 2.4 19.3 0.0 130.5 0.4 66.9 1.8 0.0 0.1 1.1 54.2 41.6 0.6 0.7 19.4 1.2 6.6 0.2 1128.1 131.5 421.5 270.3 0.7 0.4 0.9 578.1 0.5 164.8 0.0 0.0 0.0 4.5 0.0 3.1 0.0 0.4 2.4 0.0 0.0 0.4 1.2 0.0 0.3 0.0 0.0 0.1 0.5 10.1 10.8 8.7 14.4 10.0 14.9 14.0 19.4 11.2 9.8 11.7 12.3 127.3 3.2 0.6 2.0 3.1 164.4 4.3 0.6 9.1 0.7 12.7 33.5 8.7 4.3 0.6 7.3 0.0 17.6 41.2 0.4 0.0 15.1 4.0 13.2 453.2 101.4 0.0 2.7 0.1 0.4 25.1 1455.4 13.3 10.3 0.0 36.1 123.1 1.4 35.3 0.0 0.8 0.1 0.0 3.1 219.7 23.7 605.5 11.7 181.5 44.0 2.4 3.1 32.0 0.0 0.1 5.9 1.0 472.1 12.1 11.2 0.0 0.4 0.1 0.5 295.9 284.8 555.2 3.7 11.5 4.6 140.4 40.4 32.7 125.3 0.4 3.9 COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414207 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 355.2;Fibroblasts: 567.9;Leydig cells: 315.1;Smooth muscle cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3311.7;ASC TERT1: 4227.5;BJ hTERT+: 1279.6;HSkMC: 2705.3" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 12.0" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 1000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" 150.8 8.3 0.1 126.5 1.0 0.4 74.5 0.2 3.0 212.6 5.2 94.8 22.9 156.3 10.2 44.1 91.8 236.4 61.2 2.4 0.1 5.7 10.3 65.8 30.7 0.6 0.1 123.8 21.1 17.3 2.8 132.9 0.7 47.7 51.7 0.0 45.2 55.4 32.5 35.7 46.6 391.3 0.8 19.0 41.5 15.6 1.8 24.8 38.1 62.3 16.1 188.4 62.7 0.9 0.2 0.5 0.6 0.0 3311.7 4227.5 60.9 815.6 1279.6 167.0 188.2 0.0 0.1 4.5 0.1 818.7 67.4 0.6 0.7 0.9 98.8 2.0 0.1 0.0 0.0 0.0 669.9 0.0 0.4 2705.3 0.0 596.3 1.8 7.8 0.2 0.0 0.1 0.6 6.2 0.0 0.1 0.2 0.5 0.0 7.4 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 17.3 0.0 0.4 2.9 19.0 45.1 27.6 142.4 1.0 0.0 0.1 859.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 3.0 2.4 0.1 0.6 0.1 0.7 0.8 1.8 0.9 48.2 0.0 10.5 0.3 0.6 61.1 0.5 0.5 1.8 1.0 2.5 2.9 10.6 1.5 3.8 0.0 0.0 4.5 1.2 0.0 0.0 0.9 5.4 11.0 355.2 17.6 0.0 0.0 0.8 0.0 6.2 567.9 6.6 8.7 1.3 1.8 25.4 1.8 8.1 0.0 0.4 0.0 0.0 1.3 85.4 9.6 315.1 5.5 72.9 29.0 2.2 1.1 1.0 0.0 0.3 2.4 0.0 103.4 2.0 0.9 0.0 0.2 1.0 2.3 32.9 19.2 197.7 1.5 1.3 3.3 61.5 5.7 9.3 48.7 0.0 1.0 COL6A5 "COL29A1, FLJ35880, VWA4" ENSG00000172752 "Collagen type VI alpha 5 chain" 3 130345516-130484844 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lung: 5.6;skin 1: 6.2" "Group enriched" "Detected in some" 6 "Basal keratinocytes: 3.4;Early spermatids: 5.6;Erythroid cells: 3.8;Fibroblasts: 5.5;Langerhans cells: 5.2;Late spermatids: 3.0;Suprabasal keratinocytes: 3.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 64 "HDLM-2: 15.8" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA043138 Uncertain "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA043138: AB_10796687" "unprognostic (3.45e-2)" "unprognostic (4.08e-2)" "unprognostic (6.01e-3)" "unprognostic (2.32e-1)" "unprognostic (3.42e-2)" "unprognostic (1.46e-6)" "unprognostic (8.44e-2)" "unprognostic (2.07e-3)" "unprognostic (2.47e-1)" "unprognostic (1.71e-1)" "unprognostic (7.58e-8)" "unprognostic (3.85e-2)" "unprognostic (4.51e-1)" "unprognostic (1.54e-1)" "unprognostic (2.79e-2)" 0.0 0.0 0.0 0.1 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.7 0.0 0.0 0.0 1.0 0.8 0.1 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.3 0.0 3.8 0.2 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.2 3.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 3.4 0.0 0.2 0.0 0.0 0.0 COL6A6 ENSG00000206384 "Collagen type VI alpha 6 chain" A6NMZ7 3 130560334-130678155 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "parathyroid gland: 97.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.6;Fibroblasts: 20.6;Inhibitory neurons: 5.3;Oligodendrocytes: 4.6;Skeletal myocytes: 3.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SuSa: 1.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "spinal cord: 10.0" HPA045239 Uncertain "Secreted to extracellular matrix" NA NA 700000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA045239: AB_2679268" "unprognostic (4.86e-3)" "unprognostic (2.16e-2)" "unprognostic (9.91e-2)" "unprognostic (2.08e-4)" "unprognostic (2.79e-1)" "unprognostic (1.11e-5)" "unprognostic (3.74e-3)" "unprognostic (5.59e-2)" "unprognostic (1.42e-1)" "unprognostic (3.50e-2)" "unprognostic (8.90e-2)" "unprognostic (2.70e-1)" "unprognostic (2.96e-4)" "unprognostic (5.82e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (1.07e-1)" 1.8 0.0 0.0 0.0 0.2 0.2 2.5 0.2 0.3 0.0 0.0 0.0 0.0 0.6 0.3 0.9 0.3 0.1 3.3 0.0 0.0 0.0 0.8 7.3 0.0 0.0 0.0 0.2 0.0 97.8 3.6 0.7 0.0 0.0 0.0 0.3 1.5 0.0 0.1 0.4 0.0 0.5 0.0 1.2 0.1 0.4 0.1 1.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 1.1 1.3 0.0 0.9 0.0 0.0 0.0 1.1 0.2 0.4 2.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 2.9 0.1 0.0 0.0 4.6 0.0 0.0 20.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.3 0.0 0.0 0.0 1.5 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 3.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 3.3 0.8 0.0 0.4 0.0 0.9 0.1 0.2 0.0 0.0 0.0 COL7A1 "EBD1, EBDCT, EBR1" ENSG00000114270 "Collagen type VII alpha 1 chain" Q02388 3 48564073-48595329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 98.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 72.5;Basal respiratory cells: 59.3;Basal squamous epithelial cells: 67.2;Endometrial stromal cells: 45.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 41.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 65.7;HaCaT: 63.5;HBEC3-KT: 100.6;HDLM-2: 97.8;HeLa: 146.2;SiHa: 82.8" "CAB016357, HPA018877, HPA042420" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 6000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "CAB016357: AB_2229746, HPA018877: , HPA042420: AB_2677990" "unprognostic (2.69e-2)" "unprognostic (4.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-1)" "unprognostic (4.93e-2)" "prognostic favorable (6.31e-4)" "unprognostic (7.56e-2)" "unprognostic (1.25e-2)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.74e-2)" "unprognostic (0.00e+0)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.86e-2)" 0.8 1.1 1.4 3.8 1.0 0.1 4.9 2.8 2.1 24.3 0.4 2.9 1.7 12.1 6.7 21.8 6.4 4.0 3.2 0.3 6.5 7.4 1.3 1.7 1.2 7.0 3.2 3.4 0.4 0.0 2.5 1.6 3.0 34.2 0.9 1.4 11.5 12.2 3.5 98.2 4.1 2.5 2.6 6.5 2.1 3.6 6.5 1.2 0.5 0.6 1.3 6.6 29.2 0.6 0.2 25.4 1.2 0.5 9.2 12.3 31.0 65.7 40.8 16.9 10.0 0.4 0.5 0.1 2.0 15.0 15.4 63.5 0.0 100.6 3.1 97.8 0.5 0.2 146.2 4.3 25.6 0.0 0.4 19.9 58.8 34.4 26.8 23.1 0.0 0.7 0.5 0.7 2.0 0.3 0.0 0.9 3.1 1.3 1.3 0.5 2.2 0.2 9.2 0.2 0.2 0.2 82.8 0.1 0.8 3.7 1.3 0.3 0.0 5.6 3.2 3.2 50.1 1.8 1.8 0.1 49.0 0.4 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 2.8 2.1 0.3 6.5 7.0 3.2 3.0 2.6 6.5 0.6 0.4 0.0 0.0 10.7 0.2 72.5 24.1 59.3 67.2 17.7 1.0 10.2 6.6 0.0 10.6 11.0 10.4 1.4 0.1 0.6 0.0 0.9 11.8 3.1 45.3 1.4 1.8 0.0 6.8 0.7 1.0 8.3 1.1 4.0 0.0 0.8 0.4 0.7 1.6 8.4 11.6 0.7 0.0 0.3 4.2 6.3 5.0 0.8 8.8 8.4 0.1 2.6 0.0 4.0 4.4 15.6 0.1 5.7 0.0 5.7 0.2 0.3 2.5 12.9 0.0 2.0 13.4 2.6 1.5 11.3 24.2 1.2 0.8 5.0 0.2 5.8 COL8A1 "C3orf7, MGC9568" ENSG00000144810 "Collagen type VIII alpha 1 chain" P27658 3 99638475-99799226 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Fibroblasts: 53.3;Hepatic stellate cells: 102.8;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 1098.3;hTERT-RPE1: 431.9;LHCN-M2: 313.0;TIME: 471.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053107 Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053107: AB_2682046" "unprognostic (3.13e-2)" "unprognostic (2.92e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-3)" "unprognostic (2.49e-1)" "unprognostic (2.31e-2)" "unprognostic (4.83e-2)" "unprognostic (2.62e-2)" "unprognostic (4.79e-2)" "unprognostic (3.58e-2)" "unprognostic (3.71e-1)" "prognostic unfavorable (9.39e-8)" "unprognostic (2.98e-3)" "unprognostic (1.72e-1)" "unprognostic (1.38e-2)" "unprognostic (1.32e-3)" 33.0 7.0 1.7 5.8 2.9 0.0 5.7 1.8 2.6 3.8 4.4 12.4 1.0 5.2 2.7 11.1 9.1 10.8 39.1 1.3 3.0 5.9 0.9 32.8 0.9 3.1 3.9 9.2 1.2 17.9 11.3 4.2 3.4 12.7 6.9 0.5 7.0 12.0 2.3 3.2 3.7 31.5 2.7 1.0 5.3 0.5 2.6 0.4 27.5 7.8 0.5 25.0 5.4 2.5 0.1 0.4 3.0 0.3 142.2 236.4 0.2 68.5 45.7 69.6 138.6 0.0 0.3 0.1 5.9 1098.3 1.9 0.1 0.4 88.2 157.8 0.1 0.2 0.1 7.9 0.0 26.8 0.0 0.1 142.8 3.2 52.6 82.9 431.9 129.4 0.0 0.1 0.2 313.0 0.0 0.0 0.0 2.6 0.0 0.9 0.0 0.0 0.0 144.3 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.1 0.2 471.5 31.0 24.1 1.6 34.2 0.1 0.0 0.1 58.4 0.0 241.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 1.8 2.6 1.3 3.0 3.1 3.9 3.4 2.7 2.6 2.5 4.4 246.8 22.1 0.0 0.4 0.8 0.5 2.8 14.8 0.4 1.8 5.2 4.9 4.3 3.9 9.2 0.0 0.1 0.9 0.0 0.0 0.1 1.3 0.2 2.6 14.1 0.0 0.0 1.9 0.0 0.3 53.3 2.0 0.3 5.1 0.2 102.8 0.8 0.1 0.0 0.7 0.0 0.0 1.9 2.3 1.0 2.1 0.8 1.8 4.7 0.2 0.7 2.1 9.0 0.6 0.1 0.0 9.4 0.5 0.2 0.0 1.6 1.0 0.6 0.0 1.9 51.6 0.3 0.3 1.0 0.6 0.4 0.9 0.1 0.0 0.5 COL8A2 "FECD, FECD1, PPCD, PPCD2" ENSG00000171812 "Collagen type VIII alpha 2 chain" P25067 1 36095239-36125222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 10.2;Cardiomyocytes: 13.5;Fibroblasts: 13.4;Macrophages: 6.8;Melanocytes: 7.2;Microglial cells: 8.4;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 5.8;fHDF/TERT166: 4.3;HHSteC: 14.1;hTERT-RPE1: 18.2;THP-1: 4.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.6" HPA049788 Uncertain Uncertain "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA049788: AB_2680882" "unprognostic (9.98e-2)" "unprognostic (3.26e-2)" "unprognostic (2.51e-2)" "unprognostic (8.41e-3)" "unprognostic (8.76e-2)" "prognostic favorable (9.44e-4)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (3.50e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.35e-5)" "unprognostic (1.08e-2)" "unprognostic (6.77e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-3)" 5.2 1.2 2.5 4.4 2.2 0.5 5.6 6.1 2.4 9.0 18.3 5.9 1.4 5.7 1.6 5.8 4.2 4.8 5.4 2.3 2.9 1.1 0.6 4.6 3.1 9.0 4.2 3.3 0.8 0.7 4.0 12.8 7.1 6.1 2.0 0.4 7.4 11.4 0.6 5.5 2.4 3.7 6.1 8.5 9.1 0.9 4.2 4.9 7.5 2.1 3.5 13.3 5.9 5.7 0.0 0.0 0.0 0.0 0.5 1.0 0.1 5.8 1.7 1.6 0.9 0.2 0.1 0.0 0.8 4.3 0.0 0.3 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.1 14.1 0.0 0.0 1.7 0.1 0.7 0.0 18.2 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.4 0.1 0.1 0.0 0.5 0.5 0.5 0.0 0.2 0.4 0.0 4.7 0.1 2.3 0.3 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.5 2.2 6.1 2.4 2.3 2.9 9.0 4.2 7.1 6.1 4.2 5.7 0.6 0.0 1.8 0.3 0.0 2.2 2.2 1.8 0.0 0.1 1.3 10.2 13.5 0.0 0.7 0.0 0.0 0.4 1.4 0.0 0.0 0.4 0.1 0.2 0.2 0.7 0.0 0.0 0.2 0.2 0.3 13.4 0.5 0.3 2.5 0.5 1.1 0.0 6.2 0.0 0.4 0.0 0.0 2.0 2.7 0.2 3.1 6.8 7.2 8.4 1.2 0.3 0.0 0.5 0.1 0.6 0.0 6.0 0.1 5.3 0.0 0.0 0.2 0.2 6.6 0.7 1.4 0.0 0.3 0.1 1.3 0.8 1.2 0.3 0.0 0.4 COL9A1 ENSG00000112280 "Collagen type IX alpha 1 chain" P20849 6 70216040-70303084 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 68.8" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 310.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 25.7;NTERA-2: 8.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA074749 Enhanced "Secreted to extracellular matrix" NA NA 120000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA074749: AB_2732266" "unprognostic (2.18e-2)" "unprognostic (2.16e-1)" "unprognostic (2.25e-2)" "unprognostic (3.48e-3)" "unprognostic (5.72e-2)" "unprognostic (5.32e-4)" "unprognostic (3.24e-3)" "unprognostic (8.79e-2)" "unprognostic (1.25e-1)" "unprognostic (8.68e-2)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "unprognostic (1.54e-1)" "unprognostic (2.09e-1)" "unprognostic (2.78e-1)" "unprognostic (3.62e-2)" 0.2 0.0 5.1 0.1 5.3 0.0 0.1 4.5 5.6 0.8 68.8 1.3 0.8 0.3 0.1 0.1 0.2 0.3 9.1 5.6 5.7 1.2 0.0 0.0 0.0 7.1 5.8 0.0 0.3 0.1 5.1 0.0 6.0 15.2 0.5 9.5 1.5 0.3 0.0 0.1 0.9 0.2 5.1 0.0 1.5 4.1 5.3 0.1 0.4 0.3 0.0 1.3 2.9 6.3 0.0 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 5.3 4.5 5.6 5.6 5.7 7.1 5.8 6.0 5.1 5.3 6.3 0.6 0.0 0.0 2.3 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.1 3.7 0.0 0.0 0.0 4.2 0.0 0.0 1.0 1.9 0.0 21.4 1.2 0.1 0.8 1.2 0.0 1.4 0.2 0.0 0.5 0.0 1.7 0.0 1.0 0.0 0.0 0.1 35.3 6.7 0.5 0.0 0.0 0.0 11.6 0.0 0.1 0.0 2.8 0.1 68.5 0.0 310.1 0.6 0.0 0.8 0.4 0.0 2.3 0.0 0.1 0.0 3.2 0.0 0.3 4.2 0.6 2.3 0.1 0.0 0.0 0.0 0.1 0.8 0.1 COL9A2 "EDM2, MED" ENSG00000049089 "Collagen type IX alpha 2 chain" Q14055 1 40300489-40317813 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.2;pituitary gland: 108.1" "Cell type enhanced" "Detected in many" "Muller glia cells: 295.4;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 128.1" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 3.2;myeloid DC: 1.2" "Group enriched" "Detected in many" 6 "dendritic cells: 1.2;granulocytes: 3.2" "Group enriched" "Detected in many" 4 "HDLM-2: 98.6;Hep G2: 27.6;HMC-1: 90.3;THP-1: 105.0" "Low region specificity" "Detected in all" "HPA056316, HPA075286" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 510000 "Cluster 52: Eosinophils - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles Nucleoplasm "HPA056316: AB_2683099, HPA075286: AB_2732288" "unprognostic (1.42e-2)" "unprognostic (3.54e-2)" "unprognostic (8.94e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (4.46e-2)" "unprognostic (1.83e-3)" "unprognostic (2.06e-2)" "unprognostic (9.00e-3)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-3)" "unprognostic (2.26e-1)" "unprognostic (1.16e-3)" "unprognostic (4.28e-2)" "unprognostic (2.56e-1)" "unprognostic (5.89e-2)" "unprognostic (1.71e-2)" 2.2 3.4 42.6 3.7 71.5 10.9 5.9 58.9 51.1 12.1 21.6 6.5 5.8 5.0 1.7 1.6 11.4 8.5 2.2 38.2 49.7 24.6 0.9 4.3 5.9 65.9 74.1 1.3 2.3 21.0 108.1 1.1 66.2 13.7 3.1 23.1 16.3 24.2 0.2 4.6 10.4 1.4 52.0 9.8 16.5 2.6 58.6 1.8 12.2 0.3 3.1 12.1 2.0 86.2 12.0 0.3 1.8 0.8 2.6 1.3 7.8 0.0 0.0 0.6 1.3 0.4 6.8 3.4 10.0 0.3 0.0 2.0 0.1 0.0 0.3 98.6 1.4 2.0 0.8 27.6 1.5 0.9 90.3 4.8 0.0 0.1 0.0 0.7 0.0 1.5 0.1 19.8 0.0 2.7 1.2 2.1 2.2 0.0 1.2 2.3 0.0 6.9 0.0 14.3 1.4 2.3 0.1 11.8 1.3 6.6 15.0 105.0 0.1 0.0 11.6 0.2 0.4 1.4 0.2 3.4 1.0 12.3 0.6 0.0 0.1 3.2 0.0 0.2 0.0 0.2 0.1 0.0 1.2 0.2 0.0 0.0 0.5 0.2 0.3 0.1 0.1 0.0 42.6 71.5 58.9 51.1 38.2 49.7 65.9 74.1 66.2 52.0 58.6 86.2 0.5 0.0 3.3 26.1 10.8 1.0 3.0 8.5 0.0 2.0 7.1 9.7 1.0 7.2 10.0 25.8 0.0 3.2 2.5 7.2 0.0 11.7 0.2 13.6 0.9 0.6 12.7 0.4 0.3 0.8 0.6 2.1 26.0 20.0 26.1 1.6 1.1 0.0 3.4 0.0 0.3 6.6 2.0 0.3 22.4 0.9 2.1 6.4 1.8 3.7 22.1 295.4 1.0 62.4 128.1 4.9 9.6 0.0 4.0 6.1 5.0 0.3 12.9 10.9 0.0 1.3 1.8 3.4 6.2 0.2 0.6 1.4 2.7 1.8 13.4 13.4 COL9A3 "DJ885L7.4.1, EDM3, FLJ90759, IDD, MED" ENSG00000092758 "Collagen type IX alpha 3 chain" Q14050 20 62816244-62841159 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.7;choroid plexus: 34.4;thyroid gland: 25.4" "Cell type enhanced" "Detected in many" "Early spermatids: 116.6;Late spermatids: 401.9;Muller glia cells: 95.8;Oligodendrocyte precursor cells: 84.9;Oligodendrocytes: 68.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 30.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 143.4;Hep G2: 59.6;SK-MEL-30: 51.1;WM-115: 57.8" "Low region specificity" "Detected in all" "HPA040125, HPA058323" Supported Approved "Nucleoplasm,Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Intermediate filaments" "HPA040125: AB_10805604, HPA058323: AB_2683679" "unprognostic (1.14e-3)" "unprognostic (2.14e-2)" "unprognostic (3.93e-1)" "unprognostic (1.21e-3)" "unprognostic (4.25e-2)" "unprognostic (2.39e-2)" "unprognostic (2.33e-1)" "unprognostic (1.24e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-1)" "unprognostic (2.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.67e-1)" 1.6 1.5 17.5 0.7 35.7 0.0 2.8 22.4 21.6 3.3 34.4 12.1 0.7 1.2 0.2 1.3 1.7 0.1 6.3 13.0 16.5 2.9 0.6 0.4 0.2 37.4 31.0 1.7 7.6 0.1 14.0 0.5 24.2 3.2 0.1 1.6 23.6 1.2 0.5 1.9 3.1 0.1 20.5 0.3 2.7 20.7 31.6 0.1 25.4 0.0 0.0 2.8 3.8 39.7 0.2 0.3 0.3 0.2 0.0 0.8 143.4 0.1 0.0 0.1 0.0 1.6 0.2 0.0 13.1 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.9 0.0 8.2 59.6 0.3 0.0 0.5 2.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.3 0.0 0.0 1.0 0.7 6.4 8.2 0.0 2.5 0.0 1.8 0.0 0.1 0.0 1.5 0.2 0.1 51.1 4.6 0.2 5.4 0.0 0.0 0.7 0.1 1.0 0.2 0.1 0.0 0.2 0.0 57.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 35.7 22.4 21.6 13.0 16.5 37.4 31.0 24.2 20.5 31.6 39.7 1.6 3.2 0.0 1.0 26.1 3.2 2.2 1.2 1.8 0.9 2.1 2.5 1.6 0.0 0.2 5.5 10.4 5.1 0.4 0.7 1.9 3.6 116.6 2.7 0.4 3.7 4.2 1.3 2.5 0.0 46.4 15.3 6.1 0.7 0.0 0.6 2.5 6.8 2.2 0.0 2.0 3.3 0.0 2.2 0.9 401.9 4.1 1.7 3.6 0.0 0.5 95.8 0.0 84.9 68.9 0.1 7.3 1.5 44.0 1.2 2.3 23.7 2.5 3.7 0.0 0.8 1.0 2.9 7.8 0.9 7.0 4.0 1.4 3.7 2.0 1.0 COLEC10 CL-L1 ENSG00000184374 "Collectin subfamily member 10" Q9Y6Z7 8 118995452-119108455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 65.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.9;Hepatic stellate cells: 10.4;Inhibitory neurons: 5.4;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 4.8" "Cancer enhanced" "Detected in some" "liver cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 3.4;SK-BR-3: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 30000000 "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" "unprognostic (3.79e-4)" "unprognostic (6.25e-3)" "unprognostic (1.80e-3)" "unprognostic (7.73e-2)" "prognostic favorable (5.79e-4)" "unprognostic (1.05e-1)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.25e-2)" "unprognostic (9.02e-5)" "unprognostic (2.47e-1)" "unprognostic (1.82e-1)" "unprognostic (5.85e-5)" "unprognostic (7.12e-2)" 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.7 0.6 0.1 0.4 0.4 65.7 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 10.9 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 6.9 0.0 0.2 1.0 0.0 0.0 0.0 0.0 10.4 0.4 0.3 0.0 5.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.8 0.1 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 COLEC11 "CL-K1, MGC3279" ENSG00000118004 "Collectin subfamily member 11" Q9BWP8 2 3594832-3644644 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.2;liver: 143.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 37.4;Hepatic stellate cells: 89.3;Peritubular cells: 52.3;Proximal tubular cells: 127.1;Sertoli cells: 72.3" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HHSteC: 135.7;SH-SY5Y: 111.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA035241 Uncertain "Secreted to blood" NA NA 130000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035241: AB_10600701" "unprognostic (3.35e-1)" "unprognostic (4.73e-2)" "unprognostic (2.44e-3)" "unprognostic (2.31e-3)" "unprognostic (1.53e-2)" "unprognostic (1.40e-2)" "unprognostic (7.95e-3)" "unprognostic (5.85e-3)" "unprognostic (6.96e-2)" "unprognostic (2.04e-1)" "unprognostic (1.41e-1)" "unprognostic (6.96e-2)" "unprognostic (2.26e-1)" "unprognostic (9.27e-3)" "unprognostic (7.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.60e-1)" 13.8 40.6 1.0 0.9 1.0 1.9 3.3 4.8 1.9 1.8 6.9 2.8 3.5 1.2 0.4 1.6 4.4 54.2 46.6 1.4 0.9 24.8 143.1 2.4 1.9 1.3 0.5 46.4 13.8 1.2 5.8 2.4 1.3 3.3 0.6 0.5 0.6 1.1 0.6 1.4 3.8 1.1 0.4 3.8 3.1 7.4 1.1 4.0 17.0 0.8 0.2 7.1 1.0 1.3 0.2 1.4 0.7 2.5 0.0 0.0 11.7 0.7 0.0 0.3 0.2 0.7 0.2 0.3 4.0 0.1 0.4 0.4 0.1 0.4 0.3 0.2 0.8 0.6 1.4 5.0 135.7 0.2 1.0 1.6 0.1 0.2 0.0 0.4 0.1 0.8 11.1 0.8 0.0 0.1 0.0 0.8 0.6 0.2 0.9 0.0 0.0 0.5 0.0 0.3 2.1 111.7 1.6 1.1 0.8 0.3 0.5 1.0 0.0 0.0 0.7 0.6 0.5 3.2 26.2 1.5 0.3 1.3 0.6 0.7 0.1 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.2 0.9 0.3 0.1 0.2 0.1 0.0 1.0 1.0 4.8 1.9 1.4 0.9 1.3 0.5 1.3 0.4 1.1 1.3 7.3 0.0 0.0 0.7 0.6 1.0 0.0 0.0 2.8 0.5 0.1 0.3 1.2 0.0 0.0 0.0 0.0 1.6 0.0 0.1 17.6 0.0 0.3 1.1 22.0 4.2 0.0 0.0 2.2 0.0 1.4 37.4 0.0 0.6 0.0 1.3 89.3 7.9 2.5 0.0 0.9 0.1 0.0 1.9 0.3 0.5 7.5 0.8 3.6 1.0 0.0 1.4 0.0 0.5 0.2 0.1 0.0 52.3 0.0 0.2 0.0 127.1 0.0 0.1 72.3 0.3 18.0 1.3 11.6 0.6 0.9 1.2 0.7 27.0 0.0 0.1 COLGALT1 "FLJ22329, GLT25D1" ENSG00000130309 "Collagen beta(1-O)galactosyltransferase 1" Q8NBJ5 19 17555649-17583162 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 76.2;Hofbauer cells: 91.0;Kupffer cells: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047821 Approved Approved Vesicles "Intracellular and membrane" No No 9700 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA047821: AB_2680168" "unprognostic (2.46e-1)" "unprognostic (1.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.65e-5)" "unprognostic (2.92e-3)" "unprognostic (2.92e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.43e-2)" "unprognostic (1.09e-1)" "unprognostic (8.87e-2)" "prognostic unfavorable (3.83e-4)" 38.6 14.3 5.9 38.1 6.9 32.9 27.5 7.9 8.4 31.1 10.6 27.7 16.2 28.4 4.4 17.9 26.5 19.0 22.4 7.1 9.1 12.7 16.3 34.9 29.7 12.1 9.3 23.5 15.8 9.0 10.1 40.9 12.3 15.5 15.2 3.2 15.9 16.3 15.1 23.9 24.7 35.4 7.6 39.5 18.2 11.9 18.9 9.9 14.7 7.5 15.8 28.1 22.8 12.6 103.1 118.0 56.7 79.8 222.3 136.3 90.9 95.9 55.1 121.8 125.9 90.4 159.6 53.0 164.7 166.9 104.2 91.5 58.4 110.6 73.4 29.5 94.9 51.2 147.4 87.9 121.6 123.0 147.8 115.2 97.6 136.7 56.7 49.7 138.8 33.3 105.5 25.8 45.1 45.6 61.9 81.1 43.0 75.8 115.3 65.2 73.8 80.9 26.4 67.2 41.2 29.9 102.8 80.6 97.0 36.7 41.9 177.7 98.7 240.8 67.7 215.3 156.2 45.4 125.1 58.3 142.7 232.4 113.0 1.7 25.7 12.5 5.2 28.1 2.8 3.5 4.8 4.9 18.1 3.3 3.4 5.3 3.6 2.1 20.8 7.0 3.1 14.5 5.9 6.9 7.9 8.4 7.1 9.1 12.1 9.3 12.3 7.6 18.9 12.6 35.0 19.2 23.5 11.1 10.3 19.5 7.0 10.4 10.8 3.7 8.8 9.5 11.2 10.0 15.5 11.0 6.2 7.9 28.6 14.7 0.0 13.1 3.6 8.5 28.5 29.3 5.4 10.3 10.9 8.2 76.2 30.9 20.9 13.6 8.8 20.3 7.9 14.2 91.0 13.5 9.9 15.1 4.1 70.7 24.1 3.1 19.0 59.6 17.8 19.7 26.6 2.3 10.3 6.6 12.8 10.4 7.6 21.8 6.0 9.5 9.5 4.4 8.7 3.6 13.1 9.5 24.3 2.5 13.1 13.8 20.9 8.3 12.0 24.9 18.2 8.4 COLGALT2 "C1orf17, GLT25D2, KIAA0584" ENSG00000198756 "Collagen beta(1-O)galactosyltransferase 2" Q8IYK4 1 183929854-184037729 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 50.6" "Cell type enhanced" "Detected in many" "Astrocytes: 53.5;Excitatory neurons: 79.9;Inhibitory neurons: 71.5;Late spermatids: 76.2;Oligodendrocyte precursor cells: 115.1;Oligodendrocytes: 359.3" "Cancer enhanced" "Detected in many" "glioma: 11.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "basophil: 11.1" "Lineage enriched" "Detected in single" 30 "granulocytes: 11.1" "Cell line enhanced" "Detected in many" "Hep G2: 17.1;OE19: 13.8;SK-MEL-30: 18.6;U-251 MG: 18.0;WM-115: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031749, HPA031750" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Vesicles "HPA031749: AB_10599298, HPA031750: AB_10611252" "unprognostic (5.44e-3)" "unprognostic (3.08e-1)" "unprognostic (6.29e-5)" "unprognostic (2.08e-1)" "unprognostic (4.41e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (2.52e-1)" "unprognostic (2.00e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (5.13e-9)" "unprognostic (1.53e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (3.80e-2)" 1.7 6.4 15.7 0.8 29.3 1.1 1.5 22.7 18.6 1.0 0.0 4.3 0.5 1.8 3.1 0.7 2.8 2.3 11.4 16.5 17.3 0.8 0.2 3.7 0.3 26.8 24.0 1.3 2.3 0.5 2.2 0.1 28.7 5.3 0.9 3.5 2.9 2.2 8.8 0.3 1.0 1.7 20.2 0.5 1.9 3.5 25.8 0.3 3.3 6.3 0.5 1.8 1.5 50.6 0.1 0.0 5.7 0.4 3.0 4.4 0.1 1.8 0.7 0.8 1.0 2.8 0.2 0.0 0.5 4.4 1.1 0.0 5.6 0.0 1.4 6.6 3.3 0.4 0.0 17.1 0.1 6.0 0.1 2.6 0.0 0.8 0.1 8.4 0.0 0.2 5.7 7.2 6.1 0.2 0.3 0.3 3.9 13.8 0.0 0.5 0.0 0.0 0.0 1.2 2.2 3.5 0.3 0.0 18.6 3.7 0.0 0.3 0.1 0.7 0.7 0.1 18.0 10.8 0.1 0.1 0.5 2.8 22.5 11.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 15.7 29.3 22.7 18.6 16.5 17.3 26.8 24.0 28.7 20.2 25.8 50.6 0.1 0.0 0.0 53.5 0.0 0.4 0.5 0.0 0.0 4.4 0.3 0.3 3.5 0.0 0.0 0.0 0.0 0.1 4.1 0.0 0.0 0.6 40.3 0.2 0.5 0.9 0.0 1.3 79.9 0.0 0.0 9.9 1.5 0.5 0.0 0.2 0.0 0.1 0.3 0.0 71.5 0.1 0.0 0.3 9.5 76.2 2.1 0.9 1.8 4.7 0.0 5.7 8.2 115.1 359.3 1.2 0.0 4.1 1.9 0.2 0.0 0.3 0.0 0.4 13.1 2.3 3.1 0.3 1.3 0.0 0.4 0.0 4.5 0.4 0.0 0.4 COLQ EAD ENSG00000206561 "Collagen like tail subunit of asymmetric acetylcholinesterase" Q9Y215 3 15450133-15521751 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Neurotransmitter degradation" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 17.9" "Cell type enhanced" "Detected in many" "Astrocytes: 17.3;Excitatory neurons: 45.1;Inhibitory neurons: 46.3;Late spermatids: 16.6;NK-cells: 15.5;Oligodendrocyte precursor cells: 18.1;Oligodendrocytes: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "MAIT T-cell: 60.9" "Lineage enriched" "Detected in many" 34 "T-cells: 60.9" "Group enriched" "Detected in some" 6 "BEWO: 11.5;HDLM-2: 3.8;U-937: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045876 Approved "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA045876: AB_2679479" "unprognostic (4.08e-3)" "unprognostic (2.61e-2)" "unprognostic (2.13e-3)" "unprognostic (2.37e-1)" "unprognostic (2.11e-1)" "unprognostic (4.62e-2)" "unprognostic (1.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (1.28e-3)" "unprognostic (4.68e-1)" "unprognostic (7.00e-5)" "unprognostic (6.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-4)" 2.5 2.3 3.1 0.7 3.2 0.8 2.2 3.9 4.6 4.6 11.9 3.7 1.0 3.4 1.6 0.9 8.8 1.1 17.9 3.7 2.7 2.9 3.4 2.5 3.9 4.8 3.2 3.6 1.7 3.6 5.7 0.3 2.8 4.6 0.5 0.6 1.5 0.8 10.8 1.6 2.6 0.7 2.6 7.2 2.4 5.0 2.3 2.6 2.6 5.1 3.0 2.2 2.4 2.9 0.1 0.0 0.7 0.0 0.0 0.3 11.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 3.8 0.4 0.2 0.5 0.0 0.0 0.1 0.3 0.4 0.0 0.3 0.1 0.2 0.3 0.5 0.0 0.3 0.2 0.2 0.1 0.3 0.0 0.0 0.5 0.2 0.1 0.1 0.1 0.0 0.2 1.0 0.0 0.0 0.2 0.5 0.6 0.0 0.0 0.1 0.2 0.2 0.1 0.8 0.4 0.0 0.0 5.2 0.1 0.0 0.6 0.0 9.9 0.0 60.9 0.0 5.3 7.4 0.0 0.0 0.5 0.6 0.0 1.8 0.0 0.4 0.3 3.5 3.1 3.2 3.9 4.6 3.7 2.7 4.8 3.2 2.8 2.6 2.3 2.9 0.6 0.0 0.6 17.3 0.5 0.3 0.2 0.1 0.0 0.3 0.4 0.6 0.7 0.0 1.4 0.0 0.0 0.3 7.7 0.0 0.0 0.1 4.1 6.5 1.4 0.4 1.2 0.4 45.1 0.0 0.2 0.6 1.1 0.8 0.0 3.3 1.8 0.8 0.2 6.7 46.3 0.2 2.0 0.6 0.0 16.6 1.8 0.4 0.0 7.5 0.4 0.3 15.5 18.1 18.3 0.2 0.1 4.5 2.0 0.2 0.0 0.2 4.3 0.7 0.0 0.5 0.7 1.5 0.5 0.0 0.1 2.3 4.1 1.4 0.3 0.1 COMMD3-BMI1 ENSG00000269897 "COMMD3-BMI1 readthrough" 10 22316388-22329542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 10.1;testis: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 23.3;MOLT-4: 12.7;U-937: 23.8" "HPA030471, HPA030472, HPA036584" Uncertain Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Nuclear bodies" "Nucleoplasm, Nucleoli, Cytosol" "HPA030471: AB_2673491, HPA030472: AB_10601090, HPA036584: AB_10670803" "unprognostic (8.63e-2)" "unprognostic (2.36e-2)" "unprognostic (1.83e-2)" 0.9 2.2 0.4 1.0 1.4 0.3 0.8 1.0 1.9 1.5 0.8 0.8 0.6 0.4 0.0 1.8 1.3 0.2 3.0 0.3 1.6 0.4 0.5 0.9 1.0 1.3 0.7 0.6 0.8 0.4 0.1 0.7 0.9 0.5 0.2 10.1 1.8 2.7 6.4 0.7 0.8 0.3 0.4 0.9 1.1 6.7 1.3 2.0 0.4 2.3 1.5 1.0 0.8 2.0 2.1 6.4 3.9 0.2 2.5 2.3 0.4 0.9 1.3 1.4 5.8 7.8 1.2 1.9 0.8 3.0 5.1 1.1 2.8 2.2 1.3 23.3 2.4 5.4 1.5 0.0 1.7 0.6 3.0 2.9 3.2 3.3 0.1 4.3 1.6 8.3 1.4 2.8 0.8 0.0 12.7 0.9 0.4 3.9 2.1 1.7 3.1 1.7 0.5 1.9 0.4 2.7 5.5 1.1 0.2 1.4 0.0 4.7 6.8 2.3 3.9 1.3 0.7 4.9 0.9 3.5 1.2 23.8 0.0 7.4 2.1 3.0 3.4 2.4 3.7 7.5 3.2 4.1 2.2 7.3 2.4 1.8 0.7 4.9 1.3 0.3 6.5 4.9 0.4 1.4 1.0 1.9 0.3 1.6 1.3 0.7 0.9 0.4 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 COMP "EDM1, EPD1, MED, PSACH, THBS5" ENSG00000105664 "Cartilage oligomeric matrix protein" P49747 19 18782773-18791305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cell adhesion" Heparin-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 77.6;heart muscle: 65.3;skin 1: 80.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 19.3;Early spermatids: 37.0;Fibroblasts: 32.0;Glandular and luminal cells: 32.0;Late spermatids: 75.3;Spermatocytes: 16.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 859.6" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA077555 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA077555: " "unprognostic (1.26e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (9.08e-5)" "prognostic unfavorable (2.04e-4)" "unprognostic (8.05e-2)" "unprognostic (8.45e-2)" "unprognostic (3.62e-2)" "unprognostic (5.12e-2)" "unprognostic (1.65e-1)" "unprognostic (1.55e-2)" "unprognostic (2.18e-2)" "unprognostic (3.85e-1)" "prognostic unfavorable (1.52e-6)" "unprognostic (5.96e-3)" "unprognostic (1.44e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (6.95e-4)" 77.6 0.2 0.0 1.1 0.2 0.0 11.0 1.3 0.2 7.5 0.0 2.3 0.0 4.6 7.6 9.5 1.2 16.1 65.3 0.0 0.0 5.2 0.3 8.0 3.6 0.3 0.1 0.4 2.8 2.2 0.4 8.2 0.1 10.2 0.0 0.0 14.1 6.7 18.0 80.6 0.9 12.1 0.3 0.3 2.5 14.9 0.0 0.1 10.3 0.6 0.3 6.5 22.7 0.1 0.0 0.0 0.0 0.0 178.4 0.4 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 859.6 0.0 0.2 1.2 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.3 0.0 0.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.2 0.0 0.0 0.3 0.1 0.1 0.3 0.0 0.1 0.1 3.2 0.5 0.0 0.0 11.5 0.6 19.3 0.0 1.4 0.3 0.3 0.8 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 37.0 2.8 3.7 1.0 0.0 0.0 0.1 0.2 0.2 32.0 0.0 32.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 1.3 0.0 0.0 10.7 75.3 0.9 0.7 10.6 0.0 0.1 1.6 0.0 0.0 0.1 0.2 0.0 0.7 0.0 0.3 0.0 0.0 0.7 0.4 6.6 2.4 4.2 16.8 1.6 0.0 7.1 0.5 1.0 0.0 0.2 0.3 COMTD1 FLJ23841 ENSG00000165644 "Catechol-O-methyltransferase domain containing 1" Q86VU5 10 75233641-75236030 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 128.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 334.8;Exocrine glandular cells: 249.5;Paneth cells: 272.5;Proximal enterocytes: 435.9;Squamous epithelial cells: 285.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 30.2;PC-3: 38.3;RPMI-8226: 24.5;U-266/70: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042165 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Plasma membrane, Cytosol" "HPA042165: AB_10794042" "unprognostic (2.53e-2)" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (9.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.36e-1)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "unprognostic (3.23e-2)" "unprognostic (8.08e-3)" "unprognostic (9.35e-2)" "unprognostic (6.74e-2)" "prognostic favorable (1.88e-4)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (1.12e-1)" "unprognostic (2.35e-1)" 11.0 17.9 1.1 1.0 1.5 1.5 9.8 1.2 1.8 18.3 5.8 23.3 7.4 7.5 0.4 70.6 7.2 0.4 33.5 1.3 1.7 29.1 37.5 11.7 0.6 1.7 2.0 8.0 128.6 3.4 17.1 0.9 1.7 11.8 1.0 1.1 23.9 1.0 28.2 25.3 25.2 0.5 1.1 12.4 27.8 3.4 1.6 0.5 18.5 0.7 0.7 8.3 29.0 0.9 6.9 2.2 0.5 1.3 0.1 0.7 19.0 2.1 1.0 0.3 0.6 1.6 6.0 20.0 3.5 0.4 1.1 9.0 0.9 1.9 0.1 3.2 30.2 0.8 4.8 3.3 1.1 3.5 3.3 0.6 3.2 0.1 2.9 1.3 0.3 3.6 7.8 4.7 0.1 6.2 5.3 11.0 1.2 5.1 38.3 10.6 1.3 24.5 1.8 0.6 8.4 2.3 2.4 16.0 4.8 0.5 8.9 0.5 1.4 0.6 5.9 1.2 2.1 21.5 4.5 9.8 0.7 3.4 0.6 0.0 7.1 3.9 10.6 10.0 11.6 7.1 10.6 11.0 8.5 5.6 3.5 6.1 1.4 7.3 9.4 15.3 8.9 6.8 1.1 1.5 1.2 1.8 1.3 1.7 1.7 2.0 1.7 1.1 1.6 0.9 23.6 19.2 11.5 1.6 18.2 29.4 40.5 54.1 133.1 6.0 29.3 37.1 31.1 57.2 33.8 53.3 10.4 33.4 30.8 334.8 144.8 162.8 1.6 10.5 7.7 13.5 40.2 16.0 3.4 249.5 79.1 13.4 148.8 33.4 12.7 10.3 25.4 84.0 35.1 1.7 3.9 206.0 42.7 24.2 21.3 3.5 9.6 21.8 37.4 6.5 31.8 10.7 24.7 1.5 0.5 109.2 272.5 7.2 50.8 38.7 435.9 140.3 11.3 34.5 32.9 6.2 25.6 2.6 3.4 285.3 38.2 30.4 29.2 10.7 143.8 56.7 COP1 "CFAP78, FAP78, FLJ10416, RFWD2, RNF200" ENSG00000143207 "COP1 E3 ubiquitin ligase" Q8NHY2 1 175944831-176207286 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 28.1;Extravillous trophoblasts: 33.5;Syncytiotrophoblasts: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.99e-1)" "unprognostic (3.76e-2)" "unprognostic (4.17e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (2.95e-2)" "unprognostic (4.33e-1)" "unprognostic (2.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.52e-2)" "unprognostic (9.24e-2)" "unprognostic (1.67e-1)" "unprognostic (1.33e-2)" "unprognostic (6.68e-2)" "unprognostic (7.01e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-1)" 14.2 9.5 5.9 12.0 7.1 16.8 12.7 11.4 9.1 12.1 8.4 18.1 13.8 11.8 9.8 14.2 9.4 9.5 9.8 8.5 5.9 12.4 16.6 12.5 15.7 4.6 5.0 8.7 13.2 10.5 8.0 11.2 5.0 10.1 16.7 8.6 13.1 8.5 13.6 17.5 13.9 11.0 5.7 16.7 13.7 15.6 6.1 14.9 10.6 7.4 16.8 14.7 11.9 8.8 35.3 17.5 22.1 13.8 23.0 22.6 56.1 21.7 22.0 17.7 18.6 30.0 28.1 59.4 25.8 20.9 18.9 32.3 16.9 27.0 17.7 23.7 17.0 22.6 19.4 28.0 18.9 49.2 33.0 16.8 28.9 17.6 19.8 17.9 26.6 21.7 43.9 24.9 24.8 42.5 27.0 28.2 47.4 55.8 2.0 26.1 20.4 40.2 26.8 93.7 22.6 41.6 27.8 44.9 35.9 37.4 32.1 69.1 40.4 19.4 16.1 28.3 23.4 35.3 62.7 49.8 19.1 26.7 26.9 8.5 3.0 12.0 1.9 3.7 1.4 1.7 2.0 1.4 2.1 1.5 2.7 2.0 14.1 0.6 3.4 1.1 1.7 1.0 5.9 7.1 11.4 9.1 8.5 5.9 4.6 5.0 5.0 5.7 6.1 8.8 15.8 22.4 14.5 0.0 4.4 0.0 0.0 0.0 0.0 0.0 15.4 10.9 0.0 0.0 3.1 9.2 0.0 28.1 12.2 0.0 21.5 14.8 0.0 17.9 14.6 7.2 0.0 0.0 0.0 22.7 33.5 7.4 0.0 20.1 7.6 18.1 0.0 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 21.8 0.0 0.0 3.1 0.0 0.0 22.1 4.4 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 31.3 6.7 13.8 0.0 0.0 COPS6 "CSN6, MOV34-34KD" ENSG00000168090 "COP9 signalosome subunit 6" Q7L5N1 7 100088969-100092187 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044315 Approved Supported Nucleoplasm "Intracellular and membrane" NA NA 110000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA044315: AB_10959750" "unprognostic (1.48e-2)" "unprognostic (2.43e-2)" "unprognostic (6.56e-3)" "unprognostic (1.38e-1)" "unprognostic (5.84e-2)" "unprognostic (2.09e-2)" "unprognostic (3.62e-3)" "unprognostic (2.93e-2)" "unprognostic (2.00e-1)" "unprognostic (2.45e-2)" "unprognostic (4.96e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (6.72e-4)" "unprognostic (1.20e-1)" "unprognostic (3.58e-2)" "unprognostic (8.57e-2)" "unprognostic (8.77e-2)" 71.3 85.5 98.5 48.7 103.0 51.8 68.6 102.5 102.0 87.1 99.5 101.3 44.1 86.5 84.0 90.6 78.1 52.9 112.9 101.9 100.7 70.8 71.6 56.5 50.3 99.3 98.4 74.8 60.2 100.8 79.2 64.0 100.4 68.8 57.8 61.4 65.0 74.2 147.3 61.8 58.4 78.5 101.7 63.1 78.4 57.4 98.7 63.1 61.5 152.8 60.6 90.5 74.7 105.0 167.6 233.4 136.2 163.5 116.1 138.4 86.6 147.7 223.5 239.7 174.9 191.9 153.8 114.4 186.1 242.2 267.3 124.1 155.1 247.9 240.4 114.9 242.6 98.2 215.9 149.3 243.3 112.1 97.6 137.5 161.4 259.2 273.9 159.5 333.0 172.7 142.7 160.5 286.4 413.7 251.6 164.8 124.0 241.3 273.2 117.6 226.6 275.4 193.6 153.8 213.4 158.6 152.7 298.5 114.1 176.4 123.7 109.2 177.9 231.3 211.1 280.5 264.8 118.1 140.2 235.3 175.5 150.0 350.6 231.8 187.8 168.2 178.8 206.6 180.7 168.0 176.8 170.9 211.3 170.3 137.4 153.6 73.5 163.5 194.6 157.8 225.8 146.6 98.5 103.0 102.5 102.0 101.9 100.7 99.3 98.4 100.4 101.7 98.7 105.0 87.8 51.3 44.2 24.8 73.4 110.6 118.1 208.1 70.0 108.3 62.8 76.3 166.3 88.6 117.2 86.5 52.1 197.3 84.2 55.1 211.3 138.3 76.5 61.6 103.4 94.9 75.3 69.0 20.9 113.5 133.7 116.0 52.5 48.3 90.7 100.5 90.3 63.2 128.8 95.9 21.0 67.4 158.7 69.6 82.5 197.1 127.7 55.1 156.5 13.1 101.4 147.0 115.4 17.6 24.0 115.1 64.7 125.3 84.3 95.0 84.2 214.2 117.9 127.1 98.6 76.3 261.5 80.5 100.2 81.2 100.3 137.9 82.7 137.9 87.1 96.1 COQ6 CGI-10 ENSG00000119723 "Coenzyme Q6, monooxygenase" Q9Y2Z9 14 73949926-73963670 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 167.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051371 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" "HPA051371: AB_2681459" "unprognostic (1.41e-1)" "unprognostic (1.35e-2)" "unprognostic (2.26e-2)" "unprognostic (2.22e-1)" "unprognostic (1.12e-1)" "unprognostic (2.88e-1)" "unprognostic (1.75e-2)" "unprognostic (2.77e-1)" "unprognostic (1.21e-1)" "unprognostic (8.33e-3)" "unprognostic (9.45e-3)" "unprognostic (2.90e-1)" "prognostic favorable (1.05e-6)" "unprognostic (1.19e-1)" "unprognostic (1.94e-1)" "unprognostic (7.46e-2)" "unprognostic (1.89e-1)" 11.2 38.4 10.5 5.6 11.0 5.5 12.0 10.9 13.1 12.1 15.5 13.0 10.2 10.0 11.3 10.1 10.5 6.7 32.0 10.8 11.1 23.0 25.7 7.4 6.3 10.6 10.6 11.5 7.0 25.1 15.9 8.0 10.6 12.6 9.5 5.8 11.1 9.9 38.6 9.3 10.8 9.8 10.7 11.3 13.4 22.0 11.0 7.3 12.3 42.6 7.0 13.6 10.5 11.1 12.2 21.7 11.1 25.7 13.2 10.7 15.4 14.8 13.6 21.8 18.4 16.4 21.0 10.7 13.7 15.3 15.0 19.1 16.6 14.8 20.6 16.3 13.3 7.2 12.8 14.3 18.0 7.2 24.9 18.1 19.2 19.9 19.5 14.1 13.9 21.5 6.4 9.6 19.2 33.3 12.4 11.7 4.0 24.8 26.0 11.7 14.1 7.6 22.9 15.2 16.6 8.8 25.2 21.5 14.6 7.2 36.4 13.3 9.4 24.8 22.9 19.0 10.8 8.9 9.0 9.0 13.7 10.6 17.1 5.4 11.3 9.2 11.3 14.2 11.3 10.3 11.2 11.3 12.1 5.3 15.6 9.4 2.3 14.5 13.1 8.9 7.6 8.5 10.5 11.0 10.9 13.1 10.8 11.1 10.6 10.6 10.6 10.7 11.0 11.1 11.9 25.6 25.5 6.2 11.4 4.7 8.1 26.9 6.8 18.9 12.3 12.4 10.3 11.5 23.1 12.9 12.5 26.3 4.1 8.3 19.6 10.8 167.0 14.1 11.0 9.1 4.8 7.4 10.0 10.9 12.6 11.9 12.2 9.9 25.3 13.9 11.4 14.7 16.2 20.2 10.0 9.7 20.3 5.4 4.2 49.5 10.8 7.5 10.6 3.7 9.6 12.0 15.5 5.0 8.4 8.6 8.4 12.4 10.6 6.0 23.3 41.3 15.8 28.1 19.7 10.5 20.5 24.7 21.0 11.5 6.0 23.8 11.9 39.9 9.4 7.1 CORT MGC32686 ENSG00000241563 Cortistatin O00230 1 10450031-10451998 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 12.9" "Cell type enhanced" "Detected in some" "Adipocytes: 2.3;Early spermatids: 4.9;Late spermatids: 5.1;Spermatocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "PC-3: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted in brain" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.25e-2)" "unprognostic (1.79e-2)" "unprognostic (1.65e-1)" "unprognostic (3.70e-3)" "unprognostic (8.87e-2)" "unprognostic (1.67e-2)" "unprognostic (1.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.94e-3)" "unprognostic (7.08e-7)" "unprognostic (2.01e-1)" "unprognostic (9.01e-4)" "unprognostic (1.62e-1)" "unprognostic (1.02e-1)" "unprognostic (3.02e-1)" "unprognostic (2.14e-4)" 0.5 0.5 5.4 0.1 12.9 0.3 0.4 2.3 6.2 0.7 1.8 0.8 0.8 0.4 0.3 0.4 0.5 0.3 0.4 4.8 3.4 1.4 1.0 0.4 0.1 1.7 1.8 0.6 0.5 0.2 1.8 0.9 1.6 0.9 0.2 1.0 0.4 0.1 0.2 0.4 0.8 0.1 1.6 0.4 0.6 1.9 4.1 0.2 0.8 0.1 0.0 0.4 0.4 3.7 0.7 1.7 0.5 0.7 0.2 0.0 0.4 0.6 0.1 0.1 0.1 1.4 0.2 0.6 0.4 0.0 0.2 0.5 0.0 0.0 0.0 1.2 1.3 0.8 1.5 1.5 0.0 0.9 0.4 0.1 0.2 0.2 0.1 0.2 0.0 0.6 0.6 0.4 0.0 1.5 0.2 1.5 0.1 0.0 2.2 0.5 0.9 0.2 0.1 0.5 0.6 0.4 0.3 0.5 0.5 0.3 0.3 0.0 0.6 0.0 1.0 0.9 0.2 0.3 1.5 0.5 0.2 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.4 12.9 2.3 6.2 4.8 3.4 1.7 1.8 1.6 1.6 4.1 3.7 2.3 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.1 4.9 0.3 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.1 1.8 0.4 0.3 0.3 0.0 0.0 0.0 0.1 0.2 COX6A2 ENSG00000156885 "Cytochrome c oxidase subunit 6A2" Q02221 16 31427731-31428360 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 46 "heart muscle: 3905.3;skeletal muscle: 6742.0;tongue: 2096.1" "Cell type enriched" "Detected in some" 18 "Cardiomyocytes: 4861.8" "Group enriched" "Detected in many" 5 "head and neck cancer: 9.3;liver cancer: 2.9;prostate cancer: 3.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 150 "NK-cell: 15.0" "Lineage enriched" "Detected in single" 150 "NK-cells: 15.0" "Cell line enriched" "Detected in some" 4 "U-266/84: 13.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 16: U-266 - Nucleosome" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.66e-1)" "unprognostic (1.73e-3)" "unprognostic (2.09e-2)" "unprognostic (1.25e-2)" "unprognostic (1.68e-2)" "unprognostic (3.88e-1)" "unprognostic (5.61e-2)" "unprognostic (7.20e-2)" "unprognostic (8.71e-2)" "unprognostic (6.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.65e-1)" 1.9 0.9 1.8 0.1 1.3 0.0 2.9 2.3 2.3 0.4 0.2 1.4 1.1 1.0 0.0 74.8 0.9 0.0 3905.3 0.9 2.1 4.5 15.9 3.3 0.4 1.6 2.6 1.2 3.0 2.9 11.9 0.1 7.3 38.9 0.0 1.0 92.1 0.1 6742.0 3.5 1.2 0.0 0.8 0.5 1.3 1.3 2.6 0.5 2.0 2096.1 0.1 0.3 1.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.1 1.8 1.3 2.3 2.3 0.9 2.1 1.6 2.6 7.3 0.8 2.6 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.4 4861.8 2.8 0.0 3.7 0.0 0.0 0.4 0.0 5.9 0.0 0.0 0.0 0.1 48.8 0.0 0.0 0.0 0.4 0.0 96.2 0.0 0.1 0.0 0.2 0.4 75.7 2.9 3.3 0.0 0.1 0.0 1.6 0.0 0.8 0.3 1.3 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.1 1.3 24.9 0.0 4.2 19.7 258.0 53.7 0.2 1.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 COX7A1 "COX7A, COX7AH" ENSG00000161281 "Cytochrome c oxidase subunit 7A1" P24310 19 36150922-36152449 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 18 "heart muscle: 2260.5;skeletal muscle: 6947.0;tongue: 4960.0" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 21879.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 162.5;ASC TERT1: 122.3;BJ: 84.7;BJ hTERT+: 102.7;fHDF/TERT166: 178.6;HHSteC: 91.4;HSkMC: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (5.48e-2)" "unprognostic (1.19e-1)" "unprognostic (6.13e-3)" "unprognostic (6.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (9.93e-2)" "unprognostic (1.92e-1)" "unprognostic (1.41e-1)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (7.84e-3)" "unprognostic (7.27e-3)" "unprognostic (9.44e-2)" "unprognostic (6.23e-2)" "unprognostic (1.54e-2)" 269.2 91.5 197.5 20.4 198.8 2.1 105.9 195.3 256.5 70.6 197.2 122.8 14.9 54.6 39.3 82.3 57.8 31.9 2260.5 210.0 214.7 86.9 11.9 63.3 12.0 197.7 188.7 46.0 40.6 147.8 105.6 27.4 199.5 86.6 23.7 49.7 88.0 119.1 6947.0 33.8 36.7 85.1 192.1 34.4 46.7 9.7 200.0 85.8 54.8 4960.0 7.3 88.5 50.1 217.9 0.5 5.9 0.6 0.1 162.5 122.3 0.0 84.7 102.7 3.4 0.0 0.0 1.8 1.4 13.0 178.6 0.0 0.7 0.0 0.0 0.8 0.2 1.8 0.4 2.1 0.3 91.4 0.0 0.8 109.0 0.0 0.0 0.0 0.0 11.3 0.0 0.6 0.7 0.0 0.8 0.0 0.7 1.0 0.6 1.2 0.2 0.0 0.4 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.2 0.6 0.1 20.7 0.0 1.3 0.5 0.4 0.8 1.9 0.7 0.2 0.8 1.2 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 197.5 198.8 195.3 256.5 210.0 214.7 197.7 188.7 199.5 192.1 200.0 217.9 309.7 0.0 5.1 2.3 2.2 26.4 1.0 28.2 2.8 80.6 25.0 89.4 21879.1 18.6 11.0 22.0 45.9 1.0 1.5 0.0 817.8 13.7 17.0 6.0 124.6 360.4 0.0 5.3 5.9 14.1 0.7 602.1 0.5 3.7 45.0 5.5 259.5 7.3 24.0 67.3 4.3 0.0 26.4 10.7 30.5 90.8 224.6 5.2 284.6 3.7 0.0 31.5 0.0 2.0 2.3 6.2 0.0 281.3 1.5 3.5 0.0 183.1 10.7 84.7 184.1 328.4 463.4 2.0 3.8 4.3 19.0 1.9 4.8 17.3 0.1 0.8 COX7A2L "COX7AR, COX7RP, EB1, SIG81" ENSG00000115944 "Cytochrome c oxidase subunit 7A2 like" O14548 2 42333546-42425088 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059124, CAB073545" Enhanced Nucleoli,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "CAB073545: , HPA059124: AB_2683912" "unprognostic (3.90e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (5.45e-2)" "unprognostic (4.60e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (4.13e-5)" "unprognostic (1.17e-1)" "unprognostic (3.12e-1)" "unprognostic (1.66e-2)" "unprognostic (2.43e-1)" "unprognostic (7.07e-3)" "unprognostic (1.54e-2)" "unprognostic (2.76e-1)" "unprognostic (5.53e-2)" "unprognostic (6.19e-2)" "unprognostic (1.02e-1)" 79.5 222.7 53.9 18.7 57.5 56.9 78.3 53.1 62.5 93.0 56.1 84.0 32.5 74.8 42.8 60.8 81.0 22.7 102.6 56.2 56.9 130.2 113.9 64.0 32.3 54.8 53.2 127.6 89.8 71.8 128.0 22.8 55.9 71.6 39.2 62.4 67.2 32.4 83.3 72.1 66.0 28.0 53.0 65.9 99.9 54.5 54.8 42.0 56.6 39.3 35.0 74.2 70.4 53.4 72.1 50.7 49.0 54.0 92.4 121.8 55.8 58.2 85.8 51.5 66.0 56.9 48.9 63.1 54.8 71.9 70.0 30.3 65.5 65.9 80.1 99.5 47.5 46.0 31.9 95.5 106.2 66.5 42.5 123.7 128.6 55.5 132.6 78.5 77.4 49.7 64.1 101.1 83.9 68.6 75.3 96.8 45.3 91.6 48.1 40.7 87.5 51.6 84.6 57.4 55.8 63.7 25.7 60.4 166.1 58.2 43.2 73.3 60.1 45.4 61.2 55.3 57.1 84.1 98.7 46.0 63.1 68.8 39.9 103.7 78.6 43.2 57.9 71.1 75.6 72.6 70.4 67.1 84.4 61.9 77.8 67.0 34.1 69.1 80.1 99.0 87.3 189.3 53.9 57.5 53.1 62.5 56.2 56.9 54.8 53.2 55.9 53.0 54.8 53.4 150.7 32.1 76.3 11.4 152.5 265.6 197.9 387.2 135.5 114.8 206.8 237.6 158.7 171.6 173.4 149.0 37.5 228.1 163.4 103.8 645.6 239.1 27.4 189.5 133.3 144.0 288.7 188.7 28.2 229.5 316.2 128.5 123.8 175.9 87.0 155.8 132.1 222.3 234.0 131.2 26.1 285.8 282.8 236.3 225.1 26.3 161.8 161.6 220.5 19.7 298.4 326.8 166.9 13.6 24.5 202.1 173.0 158.7 167.7 214.2 247.1 492.4 160.9 123.6 111.7 137.6 175.2 220.4 270.8 162.7 245.5 329.6 161.8 296.2 257.0 241.7 CP ENSG00000047457 Ceruloplasmin P00450 3 149162410-149221829 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Copper transport, Ion transport, Transport" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 1871.4" "Cell type enhanced" "Detected in many" "Club cells: 558.1;Glandular and luminal cells: 406.0;Hepatocytes: 1687.2;Muller glia cells: 720.5;Respiratory ciliated cells: 318.4" "Cancer enhanced" "Detected in many" "liver cancer: 98.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "EFO-21: 318.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001834, CAB008591" Supported "Secreted to blood" NA NA 160000000000 440000000000 "Cluster 62: Liver - Hemostasis" "Cluster 38: EFO-21 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "CAB008591: AB_1613734, HPA001834: AB_1078502" "unprognostic (3.58e-1)" "unprognostic (4.24e-1)" "unprognostic (9.61e-2)" "unprognostic (1.80e-2)" "unprognostic (4.14e-2)" "unprognostic (1.02e-2)" "unprognostic (1.06e-1)" "unprognostic (2.97e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "unprognostic (6.03e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (1.14e-7)" "unprognostic (2.68e-2)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (2.70e-1)" 13.0 2.3 17.9 2.2 18.1 0.9 20.8 18.7 29.8 70.2 129.2 13.0 9.8 14.8 0.0 5.6 8.3 1.1 39.2 17.5 33.0 9.5 1871.4 13.4 18.9 28.1 20.3 0.8 6.5 3.9 28.6 3.4 24.9 7.9 16.4 246.5 39.9 0.9 2.6 13.0 20.8 2.4 19.2 23.1 3.0 1.5 20.1 0.5 16.1 8.3 20.0 23.9 2.3 29.0 0.2 18.8 15.6 0.0 3.3 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 318.8 0.0 29.4 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.4 32.7 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.2 2.5 5.4 0.0 0.0 0.0 0.4 6.7 16.2 0.0 0.2 0.3 1.0 0.1 0.4 0.0 0.4 0.0 0.2 1.7 0.2 0.2 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 17.9 18.1 18.7 29.8 17.5 33.0 28.1 20.3 24.9 19.2 20.1 29.0 2.3 19.2 76.6 3.3 10.6 3.3 8.3 28.6 0.6 6.9 14.0 0.6 0.6 65.8 558.1 9.2 6.2 0.1 0.3 0.1 0.0 83.4 0.9 190.5 51.0 12.6 0.0 34.7 1.5 21.4 0.2 16.3 0.0 406.0 2.5 0.1 34.6 1687.2 0.6 5.0 1.4 0.2 8.2 44.6 6.9 1.2 0.3 4.0 0.0 6.5 1.6 720.5 1.0 0.5 2.0 69.3 0.0 0.4 0.3 19.5 0.0 0.3 318.4 24.8 0.0 0.8 15.3 0.0 0.1 0.8 2.6 0.3 4.9 0.1 0.1 79.0 CPA1 CPA ENSG00000091704 "Carboxypeptidase A1" P15085 7 130380339-130388114 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2326 "pancreas: 237498.3" "Cell type enriched" "Detected in some" 19 "Exocrine glandular cells: 10133.0" "Cancer enriched" "Detected in some" 639 "pancreatic cancer: 1377.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AN3-CA: 11.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA021836, CAB025197, HPA052215" Enhanced "Secreted to digestive system" NA NA 110000000 "Cluster 25: Pancreas - Digestion" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "CAB025197: , HPA021836: AB_1846005, HPA052215: AB_2681764" "unprognostic (8.41e-2)" "unprognostic (9.24e-4)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (3.97e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-6)" "unprognostic (4.99e-1)" "unprognostic (1.67e-1)" "unprognostic (2.16e-1)" "unprognostic (4.37e-2)" 27.9 4.8 0.2 5.6 0.2 4.7 13.6 0.1 0.2 11.9 1.2 4.5 33.6 5.0 0.1 6.9 3.7 0.2 43.5 0.2 0.3 4.6 12.9 3.3 8.7 0.1 0.1 102.1 237498.3 0.0 5.0 18.4 0.1 6.9 0.0 0.2 39.5 0.1 4.7 6.6 20.8 0.4 0.2 7.7 21.3 5.4 0.2 0.1 3.0 0.4 0.0 2.8 4.0 0.4 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.0 1.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.2 0.2 0.3 0.1 0.1 0.1 0.2 0.2 0.4 0.1 3.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.9 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.9 12.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 10133.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.9 1.2 0.0 1.0 44.5 2.1 0.0 0.0 0.0 527.2 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.1 0.0 16.2 2.7 0.9 5.5 0.0 0.0 1.6 0.0 2.5 0.0 0.1 CPA2 ENSG00000158516 "Carboxypeptidase A2" P48052 7 130266863-130289798 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 416 "pancreas: 45360.2" "Cell type enriched" "Detected in some" 10 "Exocrine glandular cells: 4973.8" "Cancer enriched" "Detected in many" 60 "pancreatic cancer: 411.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.2;CACO-2: 3.8;RH-30: 3.0;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA020342, HPA021317" Enhanced Approved "Golgi apparatus" "Secreted to digestive system" NA NA 1500000 "Cluster 25: Pancreas - Digestion" "Cluster 39: CACO-2 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" "HPA020342: AB_1846007, HPA021317: AB_1846008" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (4.21e-2)" "unprognostic (1.82e-2)" "unprognostic (1.38e-1)" "unprognostic (6.76e-2)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (3.84e-5)" "unprognostic (7.52e-2)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (8.48e-2)" 5.5 1.0 0.3 0.7 0.8 0.4 2.6 1.0 0.9 1.9 0.2 1.3 17.4 0.8 0.1 1.5 0.7 0.0 8.4 0.3 0.6 0.9 2.6 0.7 1.4 2.8 1.3 19.7 45360.2 0.0 1.4 3.2 2.5 1.5 0.4 0.8 7.8 0.0 0.8 1.1 30.6 0.0 1.2 1.2 108.9 2.2 1.1 0.1 0.6 0.0 0.0 0.5 0.8 3.1 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.8 0.0 0.0 0.5 0.0 0.3 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 3.0 0.0 0.0 0.3 1.6 0.0 0.1 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.6 0.4 0.3 0.0 0.4 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 1.0 0.9 0.3 0.6 2.8 1.3 2.5 1.2 1.1 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.6 1.9 8.1 4.3 0.0 0.0 0.9 0.0 0.0 0.1 4973.8 0.0 0.2 4.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 10.5 0.3 0.5 0.0 0.0 13.9 4.6 0.0 0.5 1.0 471.3 52.9 0.0 0.0 0.0 9.9 0.0 0.0 0.3 0.0 0.0 1.3 0.4 2.0 0.0 0.1 0.3 0.0 0.2 1.5 0.2 CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865296-148897203 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 112.0;lung: 86.3" "Cell type enriched" "Detected in some" 26 "granulocytes: 4422.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 1534 "basophil: 1115.4" "Lineage enriched" "Detected in single" 5518 "granulocytes: 1115.4" "Cell line enriched" "Detected in some" 45 "HEL: 303.3" "Not detected" "Not detected" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: AB_1078396, HPA008689: AB_1846009" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-3)" "unprognostic (9.13e-3)" "unprognostic (3.50e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (3.50e-3)" "unprognostic (5.18e-3)" "unprognostic (3.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.69e-3)" 18.2 2.6 0.0 19.9 0.4 25.7 20.9 0.0 0.0 59.4 0.3 39.2 27.3 26.1 19.3 41.1 6.6 112.0 6.2 0.0 0.0 3.3 2.7 86.3 11.2 0.0 0.0 0.9 21.0 2.8 0.9 1.7 0.0 18.5 56.6 0.0 12.1 15.1 1.6 17.7 45.9 25.7 0.0 1.1 45.3 3.8 0.0 14.9 0.9 10.2 15.1 54.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 303.3 0.0 0.0 0.2 0.2 6.7 0.2 0.0 0.1 0.3 0.5 3.8 0.0 0.1 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1115.4 0.0 0.7 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 2.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.1 163.9 0.0 0.5 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 16.0 0.0 1.6 0.0 3.5 0.5 0.0 4422.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 5.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 6.7 0.3 0.0 0.0 8.7 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.3 0.0 41.7 0.0 0.0 0.3 CPA4 CPA3 ENSG00000128510 "Carboxypeptidase A4" Q9UI42 7 130293134-130324180 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.6;skin 1: 57.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 17.7;Basal respiratory cells: 23.7;Exocrine glandular cells: 54.1;Fibroblasts: 11.5;Suprabasal keratinocytes: 31.0" "Cancer enhanced" "Detected in many" "cervical cancer: 10.0;head and neck cancer: 9.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 140.1;hTERT-RPE1: 261.0;LHCN-M2: 284.2;U-2 OS: 151.0;U-87 MG: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA021030 Approved Nucleoplasm,Centrosome,Cytosol "Secreted in other tissues" NA Yes 390000 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Centrosome, Cytosol" "HPA021030: AB_1846010" "unprognostic (7.60e-3)" "unprognostic (4.00e-2)" "unprognostic (1.59e-3)" "unprognostic (3.63e-3)" "unprognostic (2.24e-2)" "unprognostic (2.91e-2)" "unprognostic (2.78e-2)" "unprognostic (4.36e-3)" "unprognostic (3.23e-1)" "unprognostic (5.79e-2)" "unprognostic (2.37e-3)" "unprognostic (6.49e-2)" "unprognostic (6.21e-10)" "unprognostic (2.39e-1)" "unprognostic (1.67e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (1.31e-4)" 5.0 4.4 0.4 0.4 0.4 0.1 3.5 0.5 1.7 15.3 0.5 0.0 0.0 0.2 0.3 21.6 0.4 0.1 1.1 0.6 2.1 0.6 0.1 0.4 0.2 1.1 0.7 0.1 12.7 0.0 0.5 2.0 1.1 0.2 0.0 0.2 6.7 0.0 0.3 57.1 0.2 0.8 0.6 3.3 0.4 0.3 1.2 0.8 0.0 0.0 0.9 0.0 12.6 1.1 95.3 5.0 0.3 0.3 0.7 1.5 0.1 74.6 140.1 74.9 18.5 0.7 8.1 0.1 14.3 31.9 75.2 5.5 0.0 41.3 76.7 0.4 0.3 0.0 33.3 2.1 1.8 0.3 0.2 1.0 65.2 6.7 9.4 261.0 0.3 0.1 0.0 0.2 284.2 0.2 0.0 0.0 0.8 0.4 11.1 0.3 75.4 0.1 34.5 4.0 0.2 0.0 49.9 23.3 0.5 28.0 0.5 0.4 57.3 18.1 151.0 6.2 7.4 0.2 0.2 0.1 272.7 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.5 1.7 0.6 2.1 1.1 0.7 1.1 0.6 1.2 1.1 0.0 3.2 0.5 0.0 0.0 17.7 0.5 23.7 0.6 0.0 4.2 2.8 0.3 0.0 8.5 0.0 0.0 5.6 0.1 0.0 0.0 0.5 0.4 0.4 0.2 0.3 0.0 0.0 0.4 54.1 1.2 11.5 0.0 2.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.2 0.0 0.3 3.6 1.0 0.6 0.0 0.0 0.0 0.5 7.9 0.0 0.0 0.0 0.9 0.0 0.1 2.9 0.0 0.0 1.3 0.4 0.1 0.7 10.0 31.0 9.4 0.1 0.0 0.0 1.6 CPA5 ENSG00000158525 "Carboxypeptidase A5" Q8WXQ8 7 130344816-130368730 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 33.6" "Group enriched" "Detected in some" 23 "Early spermatids: 76.1;Late spermatids: 144.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 16.8;naive CD8 T-cell: 42.5;T-reg: 56.4" "Lineage enriched" "Detected in single" 102 "T-cells: 56.4" "Cell line enhanced" "Detected in some" "RH-30: 7.3;RT4: 3.4;U-266/84: 6.0" "Not detected" "Not detected" HPA020322 Approved Nucleoplasm "Secreted in male reproductive system" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 83: Testis - Spermatogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA020322: AB_10960562" "unprognostic (2.44e-1)" "unprognostic (3.76e-1)" "unprognostic (1.50e-1)" "unprognostic (5.94e-2)" "unprognostic (4.96e-2)" "unprognostic (7.10e-3)" "unprognostic (1.64e-2)" "unprognostic (1.41e-2)" "unprognostic (3.26e-1)" "unprognostic (5.02e-2)" "unprognostic (5.83e-4)" "unprognostic (1.43e-1)" "unprognostic (8.88e-13)" "unprognostic (5.16e-2)" "unprognostic (1.32e-1)" "unprognostic (8.81e-2)" "unprognostic (3.08e-2)" 0.3 0.2 0.3 0.1 0.2 0.2 0.1 0.2 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.2 0.0 0.0 1.9 0.3 0.4 0.0 0.5 0.0 1.2 0.6 0.4 0.1 0.0 0.0 0.0 0.0 0.2 1.0 0.7 0.0 0.2 1.8 0.0 33.6 0.5 2.2 0.3 0.0 0.9 0.6 0.0 0.4 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.3 2.1 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.0 0.0 1.2 0.5 0.5 0.8 0.3 0.0 0.0 0.0 0.7 0.0 0.9 0.9 0.0 0.6 0.0 1.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 7.3 0.2 1.0 3.4 0.9 0.1 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 6.0 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.6 0.0 16.8 8.6 0.0 0.0 4.2 42.5 0.0 0.0 0.0 0.0 56.4 5.8 0.3 0.2 0.2 1.0 0.4 0.5 0.3 0.4 0.4 0.2 0.5 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.0 0.0 1.8 0.0 3.1 0.0 0.0 0.0 0.1 76.1 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 144.1 0.9 0.1 0.0 0.0 0.9 0.0 2.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 3.8 2.6 0.0 0.0 4.7 4.0 0.0 0.0 0.1 CPA6 CPAH ENSG00000165078 "Carboxypeptidase A6" Q8N4T0 8 67422038-67746378 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.3;prostate: 2.7;retina: 2.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 31.7;Early spermatids: 21.7;Microglial cells: 12.2;Muller glia cells: 22.5;Pancreatic endocrine cells: 21.5;Paneth cells: 12.8;Prostatic glandular cells: 11.3;Urothelial cells: 36.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.5;EFO-21: 1.5;Hep G2: 3.4;OE19: 1.5" "Region enriched" "Detected in some" 9 "olfactory bulb: 12.6" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (2.85e-2)" "unprognostic (1.95e-1)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (2.58e-1)" "unprognostic (2.24e-1)" "unprognostic (2.08e-1)" "unprognostic (2.88e-1)" "unprognostic (9.35e-2)" "unprognostic (1.65e-1)" "unprognostic (5.23e-2)" "unprognostic (6.99e-2)" "unprognostic (3.57e-4)" "unprognostic (9.61e-5)" "unprognostic (1.75e-1)" "unprognostic (9.09e-2)" "unprognostic (1.41e-2)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.3 2.2 0.0 0.2 0.0 0.0 0.2 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 31.7 0.0 5.7 0.2 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 21.7 0.1 0.0 0.1 2.4 0.0 1.6 0.4 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.1 1.7 1.3 2.2 0.0 0.0 0.0 3.2 1.8 0.2 0.0 12.2 0.1 22.5 0.0 3.0 1.3 21.5 12.8 0.0 0.0 11.3 0.0 0.0 0.0 1.0 0.0 0.1 0.3 0.0 0.0 0.8 0.0 0.0 0.6 0.0 5.7 36.6 CPAMD8 "K-CAP, KIAA1283, VIP" ENSG00000160111 "C3 and PZP like alpha-2-macroglobulin domain containing 8" Q8IZJ3 19 16892951-17026815 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.7;prostate: 34.1;seminal vesicle: 36.1" "Cell type enhanced" "Detected in many" "Adipocytes: 19.5;Alveolar cells type 1: 22.4;Alveolar cells type 2: 29.8;Collecting duct cells: 27.6;Leydig cells: 31.4;Prostatic glandular cells: 19.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "BEWO: 19.5;EFO-21: 12.6;T-47d: 34.4" "Region enriched" "Detected in single" 8 "spinal cord: 5.6" "HPA031327, HPA031328, HPA031329, HPA031330" Uncertain Uncertain "Focal adhesion sites" "Secreted to blood" NA NA 2700000 "Cluster 21: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 43: Cardiomyocytes - Nuclear processes" "Focal adhesion sites" "HPA031327: AB_2673829, HPA031328: AB_2673830, HPA031329: , HPA031330: AB_10603788" "unprognostic (4.71e-3)" "unprognostic (1.07e-2)" "unprognostic (4.20e-2)" "unprognostic (2.76e-2)" "unprognostic (4.32e-2)" "unprognostic (4.06e-3)" "unprognostic (7.85e-2)" "unprognostic (9.30e-2)" "unprognostic (1.58e-1)" "unprognostic (2.71e-2)" "unprognostic (1.62e-1)" "unprognostic (4.24e-2)" "unprognostic (8.69e-2)" "unprognostic (1.01e-3)" "unprognostic (2.08e-1)" "unprognostic (8.45e-2)" "unprognostic (1.80e-2)" 6.8 2.5 7.9 0.5 15.6 0.5 6.2 35.7 3.7 7.7 4.3 1.0 0.3 2.2 10.5 0.5 1.8 0.3 23.8 2.4 7.2 19.0 0.8 15.0 0.2 23.5 26.2 1.6 0.4 3.2 4.1 4.2 21.3 34.1 0.1 0.5 2.8 36.1 2.8 1.6 1.2 0.4 25.5 1.7 0.8 2.3 17.8 1.2 21.0 2.9 0.3 1.6 3.1 32.0 0.0 0.0 0.8 0.0 0.0 0.0 19.5 0.0 0.1 0.0 0.0 0.0 0.0 0.5 12.6 0.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 1.1 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 3.2 0.7 0.0 0.0 1.9 0.0 0.1 0.5 2.8 0.1 0.0 0.0 0.6 0.0 0.1 34.4 0.2 0.0 0.1 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 15.6 35.7 3.7 2.4 7.2 23.5 26.2 21.3 25.5 17.8 32.0 19.5 22.4 29.8 3.6 0.5 0.9 10.1 5.8 1.2 2.3 7.5 9.0 6.1 1.5 10.7 27.6 0.0 9.1 0.4 1.0 0.0 0.9 1.8 3.1 3.2 15.1 0.0 0.0 0.8 0.0 6.1 2.8 2.0 6.1 2.5 1.8 11.7 0.3 3.1 0.0 0.8 0.7 0.0 6.3 1.4 4.3 31.4 5.8 0.0 1.9 3.3 0.1 2.1 1.5 1.0 1.2 1.4 6.4 3.4 19.3 0.0 0.1 4.7 0.1 0.0 1.6 2.1 6.2 1.2 0.4 0.6 6.0 0.4 1.7 0.2 6.0 CPB1 ENSG00000153002 "Carboxypeptidase B1" P15086 3 148791102-148860187 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1970 "pancreas: 226925.8" "Cell type enriched" "Detected in some" 12 "Exocrine glandular cells: 7306.0" "Group enriched" "Detected in some" 312 "breast cancer: 293.8;pancreatic cancer: 641.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HDLM-2: 1.0;U-2 OS: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026158, HPA038069, HPA046340" Enhanced "Secreted to digestive system" NA NA 88000000 "Cluster 17: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "CAB026158: , HPA038069: AB_2675816, HPA046340: AB_2679628" "unprognostic (6.90e-2)" "unprognostic (3.79e-2)" "unprognostic (3.34e-2)" "unprognostic (2.64e-2)" "unprognostic (5.58e-2)" "unprognostic (3.27e-2)" "unprognostic (6.26e-4)" "unprognostic (1.90e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" "unprognostic (7.59e-2)" "unprognostic (4.51e-2)" "unprognostic (5.50e-8)" "unprognostic (3.08e-1)" "unprognostic (1.60e-1)" "unprognostic (4.93e-2)" 15.7 83.0 0.4 5.1 1.7 2.5 78.3 0.6 1.4 6.0 0.1 2.6 31.2 4.7 0.3 3.5 1.8 0.1 40.8 0.6 0.8 2.0 7.1 1.7 8.1 1.0 1.2 115.1 226925.8 0.0 2.1 13.7 1.1 4.7 4.5 0.0 36.3 0.0 2.2 2.8 17.2 0.0 0.4 19.2 28.3 2.9 1.2 0.1 1.6 0.0 0.0 1.4 2.0 3.3 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.5 0.0 0.9 0.2 0.0 0.0 0.0 4.0 0.3 0.5 1.3 0.4 0.9 0.4 0.5 1.1 0.1 0.7 0.3 1.4 1.9 1.4 0.5 0.5 0.3 0.4 0.4 1.7 0.6 1.4 0.6 0.8 1.0 1.2 1.1 0.4 1.2 3.3 2.2 0.0 0.0 1.0 0.0 0.6 0.5 0.0 0.0 0.0 8.7 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 11.6 11.2 0.0 0.1 1.1 164.9 1.3 0.3 7306.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.2 0.0 0.0 1.0 2.5 0.6 1.5 0.0 0.0 18.1 0.0 0.0 0.0 29.8 590.0 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 4.2 2.5 0.0 1.1 0.1 0.3 0.3 0.3 1.1 0.2 0.2 CPB2 "CPU, PCPB, TAFI" ENSG00000080618 "Carboxypeptidase B2" Q96IY4 13 46053186-46105033 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 84 "liver: 1484.1" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 1332.7" "Cancer enriched" "Detected in some" 112 "liver cancer: 268.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 86 "Hep G2: 173.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA004146 Approved "Secreted to blood" NA NA 8500000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA004146: AB_1078397" "unprognostic (3.44e-2)" "unprognostic (1.25e-1)" "unprognostic (2.94e-2)" "unprognostic (1.89e-2)" "unprognostic (7.69e-2)" "unprognostic (1.17e-2)" "prognostic favorable (2.06e-4)" "unprognostic (1.89e-1)" "unprognostic (2.74e-1)" "unprognostic (2.48e-1)" "unprognostic (3.17e-2)" "unprognostic (4.83e-2)" "unprognostic (3.20e-3)" "unprognostic (1.34e-1)" "unprognostic (7.10e-2)" "unprognostic (3.34e-2)" "unprognostic (9.61e-2)" 0.1 0.0 0.5 0.1 3.1 0.7 0.1 0.6 1.8 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 4.8 0.0 0.5 1.4 0.4 1484.1 17.6 0.1 1.7 2.0 0.0 0.5 0.0 0.0 0.0 2.5 0.1 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.0 0.3 0.4 0.1 0.2 2.2 0.0 0.1 0.0 0.0 0.0 0.0 5.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.6 0.3 173.2 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.1 0.2 0.2 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.1 0.1 0.0 2.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.5 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 3.1 0.6 1.8 0.5 1.4 1.7 2.0 2.5 0.3 2.2 5.1 0.0 3.2 27.0 3.9 1.7 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 190.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 1.0 0.0 10.7 4.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 15.7 1332.7 0.1 0.0 5.3 0.0 0.0 22.7 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 13.0 36.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498547 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 643.3;retina: 741.7" "Cell type enhanced" "Detected in many" "Astrocytes: 727.4;Bipolar cells: 569.1;Cone photoreceptor cells: 621.3;Enteroendocrine cells: 587.4;Leydig cells: 500.8;Muller glia cells: 530.9;Peritubular cells: 621.0;Rod photoreceptor cells: 803.3;Sertoli cells: 854.6;Smooth muscle cells: 519.4" "Cancer enhanced" "Detected in all" "glioma: 240.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 311.6;SCLC-21H: 418.2;SiHa: 629.0;SuSa: 342.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Nucleoplasm,Vesicles,Centrosome "Intracellular and membrane" NA NA 600000 "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "Nucleoplasm, Vesicles" "CAB024907: , HPA003819: AB_2667054" "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.12e-4)" 138.1 151.7 554.8 20.5 593.0 1.8 97.5 550.9 604.0 53.9 311.9 44.6 22.0 67.7 404.6 74.8 88.6 65.7 100.7 584.3 643.3 68.4 26.7 50.1 37.5 417.0 494.2 104.0 170.4 89.9 328.4 7.7 456.2 295.1 36.8 741.7 104.5 84.7 56.2 45.1 30.7 83.3 448.3 11.6 80.2 146.2 578.2 68.8 179.7 47.5 35.2 33.8 73.4 446.2 0.2 8.4 54.4 10.5 41.4 4.5 2.4 0.1 21.5 8.1 16.5 0.0 0.5 0.0 15.8 0.6 1.9 1.2 20.4 4.4 4.7 0.3 78.6 0.0 21.6 311.6 3.0 0.3 0.5 102.3 21.5 0.3 0.4 104.0 0.2 0.0 0.1 2.1 11.2 15.4 0.4 2.7 34.4 0.2 12.1 0.3 0.2 1.1 0.7 3.4 418.2 138.0 629.0 77.9 0.0 342.6 46.7 1.9 0.0 16.7 42.5 1.5 1.5 23.5 0.6 2.2 15.5 0.7 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 554.8 593.0 550.9 604.0 584.3 643.3 417.0 494.2 456.2 448.3 578.2 446.2 87.1 0.0 5.6 727.4 0.6 26.1 81.7 10.3 66.0 569.1 25.6 52.1 54.5 54.3 5.0 22.0 621.3 0.6 1.4 2.9 0.0 19.7 6.7 2.2 12.1 130.4 587.4 2.7 234.8 1.8 0.3 249.0 31.6 1.3 0.0 8.6 274.2 15.1 1.0 70.7 129.0 16.2 38.7 5.4 41.2 23.3 500.8 6.3 87.2 94.6 1.0 530.9 0.0 211.6 23.0 12.4 3.7 621.0 0.7 434.6 10.2 12.7 1.2 803.3 854.6 14.1 519.4 19.7 13.3 14.0 20.9 0.8 5.5 15.4 4.0 18.9 CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;testis: 32.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.0;Inhibitory neurons: 44.3;Oligodendrocytes: 196.5;Spermatocytes: 34.1;Spermatogonia: 62.3" "Cancer enriched" "Detected in some" 6 "testis cancer: 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-MEL-30: 37.9;U-2197: 106.0;U-87 MG: 39.1" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040396: AB_2676960" "unprognostic (3.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (3.90e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-2)" "unprognostic (7.51e-3)" "unprognostic (1.97e-3)" "unprognostic (9.50e-3)" "unprognostic (8.17e-2)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" 2.8 5.0 10.4 1.3 18.6 0.2 2.5 20.3 18.6 9.3 4.5 6.8 1.2 4.2 7.9 3.6 8.3 4.0 2.9 12.7 17.0 1.2 0.2 1.6 0.5 21.3 21.7 14.3 1.3 0.8 21.8 0.3 24.0 2.3 2.4 4.5 1.5 3.7 2.4 1.9 2.5 3.4 15.0 0.6 2.5 32.4 20.4 0.4 2.3 10.5 0.5 7.7 6.1 33.6 0.1 3.6 0.3 0.4 2.6 0.2 0.1 2.8 0.3 1.8 1.4 0.2 0.1 0.0 6.3 1.1 19.5 0.1 5.1 0.0 0.4 0.0 4.2 0.1 0.1 0.1 1.8 0.1 2.3 1.4 0.0 3.5 0.0 0.2 0.0 7.6 8.9 0.2 1.3 0.2 0.6 0.1 8.2 0.1 1.0 0.0 0.2 0.1 0.0 0.1 10.5 2.4 9.2 0.5 37.9 11.2 0.1 1.1 0.1 18.9 7.5 106.0 6.0 5.3 14.3 1.4 39.1 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.5 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.4 18.6 20.3 18.6 12.7 17.0 21.3 21.7 24.0 15.0 20.4 33.6 0.3 0.0 0.0 19.6 0.1 0.8 0.3 0.0 0.0 11.5 0.6 0.3 1.9 0.0 0.0 0.0 10.4 0.0 0.1 0.1 0.0 0.1 12.6 0.5 1.4 0.2 0.0 0.0 70.0 0.0 0.0 5.9 0.5 0.1 1.3 0.3 0.4 0.0 0.3 11.8 44.3 0.0 0.0 0.0 0.8 20.0 4.1 0.4 5.4 10.3 0.1 5.2 0.0 10.1 196.5 0.1 0.0 2.2 0.2 0.5 0.0 0.4 2.2 4.3 6.6 1.9 1.8 34.1 62.3 0.0 0.6 0.1 0.4 0.0 0.0 0.1 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 156.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.0;Alveolar cells type 2: 362.2;Kupffer cells: 368.5;Sertoli cells: 762.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.0;intermediate monocyte: 14.5;myeloid DC: 16.6;non-classical monocyte: 7.4" "Group enriched" "Detected in many" 5 "dendritic cells: 16.6;monocytes: 21.0" "Group enriched" "Detected in many" 4 "ASC diff: 71.1;ASC TERT1: 50.0;HSkMC: 91.2;SiHa: 68.9;THP-1: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 156.1 11.5 6.4 14.4 13.3 3.5 40.2 10.1 10.5 14.4 3.8 33.5 4.4 23.9 0.9 10.1 16.2 16.1 4.6 7.6 10.2 41.3 26.5 59.3 16.1 19.3 11.5 18.0 13.0 12.0 1.0 70.1 11.9 14.7 26.6 6.7 4.1 2.8 5.8 21.7 5.9 6.4 7.5 19.4 15.3 5.4 28.0 4.3 7.5 9.7 10.5 9.3 5.7 23.5 0.1 4.0 0.1 0.0 71.1 50.0 0.7 9.8 1.1 1.7 2.3 3.2 4.1 0.5 9.6 1.4 4.1 0.0 1.4 2.7 4.1 0.1 2.7 0.0 15.1 0.3 0.4 1.2 1.9 91.2 0.6 1.0 2.0 8.6 0.0 0.3 0.0 0.1 7.3 1.7 0.0 0.7 1.7 0.0 5.2 3.1 0.6 0.0 7.2 5.9 0.4 0.2 68.9 10.7 7.9 5.5 1.2 26.5 0.2 1.2 7.5 0.5 0.2 0.4 0.5 13.1 4.3 13.1 5.9 0.6 21.0 0.1 0.2 14.5 0.0 1.8 1.5 0.1 16.6 3.5 0.9 0.2 1.6 0.5 7.4 1.1 1.9 7.3 6.4 13.3 10.1 10.5 7.6 10.2 19.3 11.5 11.9 7.5 28.0 23.5 83.3 359.0 362.2 34.6 4.9 12.4 3.5 6.1 0.6 3.3 7.8 8.9 2.6 135.8 70.1 51.5 0.0 32.3 1.1 97.5 29.4 57.9 16.6 100.9 8.3 29.0 10.8 3.6 1.2 212.5 59.9 14.1 4.6 237.1 112.5 6.7 73.9 36.6 134.6 0.0 1.3 28.7 0.0 368.5 36.3 17.5 105.0 202.2 10.6 19.7 23.3 68.9 1.0 23.1 161.8 68.0 65.9 79.0 2.4 38.7 1.9 63.7 16.4 5.7 762.6 7.2 126.9 0.6 3.9 2.4 9.9 172.4 14.5 46.3 32.7 2.8 CPN1 ENSG00000120054 "Carboxypeptidase N subunit 1" P15169 10 100042193-100081869 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "liver: 81.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 37.2" "Group enriched" "Detected in some" 12 "liver cancer: 26.6;melanoma: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "SK-MEL-30: 141.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.97e-2)" "unprognostic (2.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (6.75e-2)" "unprognostic (2.93e-2)" "unprognostic (5.26e-2)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 81.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 141.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 37.2 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.6 4.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 CPN2 ACBP ENSG00000178772 "Carboxypeptidase N subunit 2" P22792 3 194339768-194351328 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 218.6" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 171.8" "Cancer enriched" "Detected in some" 32 "liver cancer: 72.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "Hep G2: 61.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA004732 Uncertain "Secreted to blood" NA NA 25000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA004732: AB_1078561" "unprognostic (4.27e-2)" "unprognostic (3.04e-1)" "unprognostic (1.42e-1)" "unprognostic (4.12e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.27e-1)" "unprognostic (8.65e-2)" "unprognostic (8.56e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.91e-2)" "unprognostic (2.40e-1)" "unprognostic (6.90e-5)" "unprognostic (8.42e-2)" 0.4 3.0 0.7 0.4 0.6 1.5 0.2 0.6 1.1 0.2 0.0 0.2 0.0 0.4 0.4 0.1 0.2 0.4 1.0 0.7 0.8 14.7 218.6 0.2 0.3 0.2 0.2 0.3 0.1 0.1 0.0 0.4 0.2 0.2 0.2 1.1 0.2 0.1 0.1 0.6 0.2 0.2 0.0 1.2 0.4 0.7 0.4 0.1 0.3 0.0 0.2 0.1 0.0 1.1 0.2 0.1 0.3 0.3 0.1 0.8 0.2 0.3 0.1 0.0 0.0 0.4 0.2 0.2 0.3 0.8 0.4 0.5 0.1 0.0 0.2 0.1 0.2 0.3 0.6 61.8 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.3 0.0 0.3 0.5 0.6 0.0 0.3 0.2 0.3 0.3 0.1 0.1 0.1 0.5 0.0 0.1 0.4 0.3 0.2 0.3 0.2 0.4 0.3 0.2 1.4 1.6 0.2 2.1 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.6 1.1 0.7 0.8 0.2 0.2 0.2 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 171.8 0.2 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 225.9" "Cell type enhanced" "Detected in all" "Astrocytes: 150.2;Oligodendrocytes: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 250.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 116.1;ASC TERT1: 131.4;hTERT-RPE1: 108.2;Karpas-707: 97.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 51000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favorable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" 46.2 35.9 22.6 25.4 33.9 31.8 34.7 28.0 26.7 75.1 20.6 39.6 29.3 46.0 36.2 25.9 39.8 57.8 51.8 21.6 27.0 80.5 70.0 32.3 22.8 32.6 27.5 87.4 46.7 60.7 25.6 39.2 33.2 40.2 33.1 16.8 32.8 54.2 13.3 20.6 35.0 64.7 25.9 31.3 32.1 13.9 30.3 8.2 225.9 33.2 17.0 46.3 38.6 38.6 0.6 2.1 2.1 0.1 116.1 131.4 0.5 35.3 55.6 12.8 26.5 2.0 0.9 0.4 27.2 59.0 15.7 1.0 2.4 2.8 12.0 31.4 4.4 28.4 1.5 17.7 25.6 4.9 37.0 69.6 6.5 15.0 3.7 108.2 6.0 0.1 27.1 97.0 29.4 1.2 0.5 14.1 2.5 0.2 5.2 4.3 0.0 0.6 26.7 13.2 2.4 0.3 10.2 0.4 28.2 25.8 12.3 28.6 21.3 51.9 4.9 0.8 11.5 7.9 0.9 0.3 32.2 21.6 33.5 32.0 71.3 45.1 27.3 49.6 27.6 5.4 20.3 24.0 51.8 7.4 17.6 24.6 250.5 25.9 47.5 14.8 22.2 40.6 22.6 33.9 28.0 26.7 21.6 27.0 32.6 27.5 33.2 25.9 30.3 38.6 46.6 12.8 12.5 150.2 11.7 19.4 25.7 21.3 9.6 12.7 12.1 27.9 27.2 42.9 13.9 47.8 29.2 12.1 40.8 9.3 17.6 22.7 5.0 6.6 43.3 27.1 13.8 7.2 24.0 10.7 1.8 123.8 10.7 8.6 38.0 43.1 51.0 48.3 54.0 10.1 31.3 7.9 24.4 56.0 44.9 9.0 72.4 39.4 78.2 131.2 33.7 43.4 39.1 44.7 299.6 11.7 9.5 73.0 11.9 12.4 42.4 56.0 9.7 16.3 52.6 71.1 67.8 5.6 3.4 2.8 13.1 6.0 23.8 38.6 12.2 13.5 CPVL ENSG00000106066 "Carboxypeptidase vitellogenic like" Q9H3G5 7 28995235-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 219.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 306.1;Kupffer cells: 290.3;Langerhans cells: 531.0;Macrophages: 266.2;monocytes: 176.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 61.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1136.9;intermediate monocyte: 953.5;myeloid DC: 1319.5" "Group enriched" "Detected in all" 52 "dendritic cells: 1319.5;monocytes: 1136.9" "Cell line enhanced" "Detected in many" "BEWO: 190.8;RPTEC TERT1: 801.1;U-266/84: 205.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 760000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: AB_2679429, HPA056466: AB_2683140" "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavorable (4.99e-4)" 44.0 23.5 7.5 66.3 8.7 59.8 24.9 48.9 12.0 28.5 39.6 28.9 32.8 17.1 34.6 25.4 19.8 42.1 79.3 6.8 9.9 96.7 52.9 57.6 92.9 15.2 11.4 18.1 7.9 5.4 10.1 84.9 15.4 17.9 25.7 0.9 5.3 21.3 12.5 19.3 46.5 34.1 11.8 219.0 15.5 34.4 8.8 66.7 128.4 8.3 35.8 50.6 15.8 23.4 1.5 0.2 20.3 0.1 0.1 0.0 190.8 0.0 0.0 1.9 0.4 59.8 0.1 0.0 90.3 0.8 94.4 3.2 51.8 4.2 0.6 0.4 47.9 67.0 1.2 144.5 0.0 0.0 0.3 0.3 5.9 0.7 1.6 0.0 0.6 27.5 45.5 0.1 1.6 0.0 63.4 0.4 31.6 0.1 16.0 0.3 0.0 0.6 801.1 22.8 11.9 9.4 53.6 125.5 101.7 97.0 15.1 49.6 0.0 0.4 0.8 0.5 12.0 17.5 205.5 1.0 0.2 25.0 20.8 19.5 1136.9 5.7 2.6 953.5 3.4 1.8 1.3 1.9 1319.5 1.2 1.2 1.2 23.4 5.8 327.8 34.8 1.5 1142.7 7.5 8.7 48.9 12.0 6.8 9.9 15.2 11.4 15.4 11.8 8.8 23.4 12.3 6.4 16.0 3.3 7.2 12.5 1.3 0.7 5.7 0.0 2.6 3.4 69.1 10.0 2.5 71.7 0.0 138.0 2.1 0.2 35.2 0.5 24.7 3.7 0.3 21.1 1.8 34.1 3.7 15.6 118.3 29.4 1.1 0.6 5.1 2.3 6.8 1.1 306.1 0.0 1.7 1.2 0.0 290.3 531.0 7.6 9.3 266.2 10.6 45.9 176.8 0.2 2.1 2.0 1.3 0.8 0.4 3.0 2.9 0.5 0.4 30.6 1.5 0.4 0.0 31.0 3.0 27.1 92.8 27.2 8.8 118.5 3.3 3.6 1.2 0.9 CPXM1 "CPX-1, CPX1, CPXM" ENSG00000088882 "Carboxypeptidase X, M14 family member 1" Q96SM3 20 2794074-2800627 "Enzymes, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 162.7;Fibroblasts: 60.1;Theca cells: 28.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebral cortex: 6.9" "Immune cell enhanced" "Detected in single" "NK-cell: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 161.7;HSkMC: 85.7;NB-4: 148.1;REH: 150.8;SH-SY5Y: 108.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 8.7" "Secreted in other tissues" NA NA 490000 "Cluster 48: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (7.48e-2)" "unprognostic (3.61e-1)" "unprognostic (6.70e-2)" "unprognostic (1.47e-2)" "unprognostic (3.41e-1)" "unprognostic (5.24e-2)" "unprognostic (1.82e-2)" "unprognostic (1.84e-2)" "unprognostic (2.98e-2)" "unprognostic (9.32e-2)" "unprognostic (7.02e-2)" "unprognostic (3.23e-2)" "prognostic unfavorable (4.62e-10)" "unprognostic (1.30e-1)" "unprognostic (1.49e-1)" "unprognostic (5.55e-3)" "unprognostic (1.27e-2)" 59.0 4.8 0.9 9.7 1.2 19.0 31.2 0.7 6.9 72.4 2.5 4.1 1.4 76.8 8.4 4.2 27.1 86.0 4.5 0.9 0.9 6.5 0.3 5.4 6.5 0.9 0.7 41.9 3.1 3.8 5.3 51.5 1.1 7.1 1.5 0.0 4.8 2.3 1.2 12.7 3.3 38.8 1.1 0.9 2.2 3.6 1.4 9.6 24.5 0.0 2.8 55.5 29.4 1.0 0.0 0.0 161.7 0.0 0.0 4.9 0.2 0.4 0.7 2.0 0.6 0.0 0.0 0.0 0.5 0.3 0.1 0.0 12.1 0.0 0.5 0.7 8.5 22.1 0.0 0.0 2.2 0.1 3.2 85.7 0.0 7.7 0.0 0.0 0.0 31.1 9.3 0.0 0.1 0.1 0.6 148.1 34.5 0.0 0.0 150.8 0.0 4.2 0.0 0.0 0.2 108.2 0.0 0.2 0.0 25.8 0.0 1.9 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.0 0.2 0.9 1.2 0.7 6.9 0.9 0.9 0.9 0.7 1.1 1.1 1.4 1.0 3.9 0.0 0.5 0.0 0.3 2.7 5.8 0.7 4.0 0.0 1.1 3.8 0.7 0.0 0.8 3.7 0.0 2.9 1.7 0.5 0.0 3.0 2.3 5.8 162.7 3.1 0.0 7.6 0.0 0.0 3.3 60.1 0.0 4.2 2.5 17.7 0.7 0.0 6.5 0.0 0.0 0.0 0.0 0.0 2.6 2.8 17.4 0.9 1.8 0.0 0.7 0.0 0.0 0.5 0.0 0.3 0.0 0.7 0.5 2.5 0.0 0.1 3.1 0.0 0.0 0.4 10.2 0.0 1.5 0.1 2.0 3.3 1.4 28.2 0.6 0.8 CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 81.3;intestine: 75.4" "Cell type enhanced" "Detected in many" "Early spermatids: 106.8;Late spermatids: 202.5;Oligodendrocytes: 35.6;Peritubular cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "BJ: 18.4;fHDF/TERT166: 71.8;SuSa: 28.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" NA NA 62000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA048375: AB_2680377" "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" 29.1 6.4 3.9 5.9 7.2 0.0 20.8 9.2 2.6 5.8 81.3 75.4 6.2 10.2 59.8 18.4 16.0 11.2 18.0 3.5 7.2 11.2 2.4 7.0 2.7 16.1 10.7 16.7 5.2 2.5 10.9 1.2 11.6 15.1 7.0 0.5 9.3 12.7 3.8 7.3 14.9 56.9 20.0 16.8 19.9 9.6 10.4 7.8 15.0 7.9 6.6 28.3 9.2 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.4 0.7 1.1 0.1 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 28.0 0.5 0.0 0.0 0.1 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 7.2 9.2 2.6 3.5 7.2 16.1 10.7 11.6 20.0 10.4 18.3 22.3 0.0 0.6 0.3 0.1 2.2 0.0 0.2 6.2 0.0 0.3 0.4 2.4 0.0 0.0 1.8 0.0 8.3 0.1 0.2 1.9 0.4 106.8 0.2 0.2 26.1 0.0 0.0 5.0 0.2 0.3 23.0 1.1 0.3 0.0 0.1 16.8 0.0 0.3 1.7 0.5 0.7 0.0 0.0 2.7 202.5 10.8 0.6 3.6 0.0 0.0 0.0 0.0 1.0 35.6 0.1 0.1 79.0 1.4 0.0 0.4 0.0 0.0 0.1 0.0 1.6 2.0 1.3 1.9 0.6 2.0 5.1 0.2 0.0 2.7 0.2 CPZ ENSG00000109625 "Carboxypeptidase Z" Q66K79 4 8592660-8619759 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 144.3" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.5;Fibroblasts: 8.5;Microglial cells: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 73.6;BJ: 39.7;BJ hTERT+: 51.7;hTERT-RPE1: 30.6;RH-30: 57.6;U-2197: 46.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA078608 Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA078608: " "unprognostic (2.58e-1)" "unprognostic (7.16e-2)" "unprognostic (4.83e-2)" "unprognostic (1.42e-1)" "unprognostic (7.77e-2)" "unprognostic (2.20e-2)" "unprognostic (2.98e-1)" "unprognostic (7.77e-2)" "unprognostic (2.30e-1)" "unprognostic (1.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (7.23e-8)" "unprognostic (4.30e-3)" "unprognostic (3.58e-2)" "unprognostic (6.13e-4)" "unprognostic (5.51e-2)" 11.1 1.8 0.3 2.7 1.0 0.0 11.8 0.5 2.9 33.3 2.3 4.6 0.8 14.6 9.1 7.4 19.9 30.7 2.8 0.8 0.4 2.0 1.4 7.1 2.8 0.7 0.5 144.3 3.2 1.8 5.2 42.1 0.8 5.9 1.8 0.1 1.5 24.2 0.2 13.8 2.6 8.4 1.2 1.4 3.3 3.1 0.3 1.5 7.8 0.0 1.0 23.0 25.1 0.9 26.1 0.4 0.0 1.6 5.0 0.5 73.6 39.7 51.7 14.5 5.8 1.7 0.7 0.0 3.7 21.3 0.3 0.0 0.0 0.0 5.4 0.0 2.9 0.0 0.3 0.7 4.4 0.0 0.0 9.2 0.0 0.0 0.0 30.6 0.0 0.0 1.2 0.0 0.9 6.1 0.0 0.1 9.2 0.2 22.0 0.1 57.6 0.0 0.0 1.1 0.1 0.1 1.4 0.5 0.1 8.3 0.3 0.0 0.0 2.0 2.6 46.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.5 2.9 0.8 0.4 0.7 0.5 0.8 1.2 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 0.0 0.6 8.5 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 CR1L ENSG00000197721 "Complement C3b/C4b receptor 1 like" Q2VPA4 1 207645113-207738416 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "bone marrow: 1.5" "Cell type enriched" "Detected in some" 18 "Erythroid cells: 128.6" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HEL: 1.3;HMC-1: 2.9;K-562: 1.6" HPA049348 Approved "Secreted in other tissues" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA049348: AB_2680723" "unprognostic (2.35e-2)" "unprognostic (8.27e-2)" "unprognostic (1.99e-1)" "unprognostic (8.89e-2)" "unprognostic (1.31e-2)" "unprognostic (5.50e-2)" "unprognostic (2.01e-1)" "unprognostic (7.45e-2)" "unprognostic (5.27e-2)" "unprognostic (8.21e-3)" "unprognostic (7.94e-2)" "unprognostic (3.02e-1)" "unprognostic (6.33e-2)" "unprognostic (2.02e-1)" "unprognostic (8.90e-2)" "unprognostic (1.31e-2)" "unprognostic (9.68e-2)" 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.1 0.5 0.5 0.0 0.3 1.8 0.0 0.1 0.0 0.0 5.9 0.4 0.2 6.9 0.2 1.8 0.0 128.6 0.4 0.0 0.1 0.2 0.0 1.0 0.0 0.0 3.6 0.2 1.2 0.0 0.4 0.0 2.0 0.3 0.3 0.4 0.0 0.5 0.0 1.0 1.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.4 0.0 0.2 3.3 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.3 0.3 0.1 0.1 0.0 0.2 CRB2 "FLJ16786, FLJ38464" ENSG00000148204 "Crumbs cell polarity complex component 2" Q5IJ48 9 123356170-123380324 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Gastrulation, Sensory transduction, Vision" "Developmental protein" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 24.9;choroid plexus: 14.1;retina: 8.1" "Cell type enhanced" "Detected in some" "Astrocytes: 40.5;Bipolar cells: 29.7;Cone photoreceptor cells: 118.9;Oligodendrocytes: 26.8;Rod photoreceptor cells: 110.1" "Group enriched" "Detected in some" 7 "glioma: 9.4;ovarian cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "AF22: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043674 Approved Supported "Intracellular and membrane" NA NA 210000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA043674: AB_10962974" "unprognostic (1.38e-2)" "unprognostic (2.39e-2)" "unprognostic (1.26e-1)" "unprognostic (2.83e-4)" "unprognostic (2.85e-2)" "unprognostic (1.14e-2)" "unprognostic (2.31e-1)" "unprognostic (3.69e-4)" "unprognostic (1.20e-1)" "unprognostic (7.28e-3)" "unprognostic (4.66e-3)" "unprognostic (3.09e-1)" "unprognostic (5.56e-5)" "unprognostic (1.31e-1)" "unprognostic (1.55e-1)" "unprognostic (4.38e-2)" "unprognostic (3.38e-1)" 1.6 0.0 14.5 0.5 21.5 0.3 0.1 11.0 12.5 0.0 14.1 0.7 0.1 1.5 0.1 0.0 1.0 0.0 0.1 13.8 13.7 5.8 0.0 0.0 0.7 24.0 20.3 0.2 0.0 0.0 1.4 0.0 14.9 0.0 0.4 8.1 0.0 0.0 0.0 0.1 0.3 0.3 22.2 0.5 0.2 0.5 24.9 0.2 0.1 0.0 0.6 0.2 0.0 23.0 0.0 0.1 32.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.1 0.3 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.6 0.0 0.0 4.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 21.5 11.0 12.5 13.8 13.7 24.0 20.3 14.9 22.2 24.9 23.0 0.0 0.0 0.0 40.5 0.5 0.3 0.1 0.0 0.0 29.7 0.0 2.2 2.8 0.0 0.0 1.8 118.9 0.1 0.0 0.7 0.0 0.0 3.9 0.4 1.3 0.4 3.0 0.0 4.2 0.0 0.1 2.5 0.0 0.1 1.3 0.0 0.0 0.0 0.2 3.3 0.4 2.8 0.0 0.0 1.0 7.7 1.8 0.1 0.0 0.0 0.1 6.1 1.0 2.0 26.8 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 110.1 0.0 0.5 0.3 0.1 0.3 0.0 0.6 0.3 0.1 0.1 5.3 0.1 CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 545.7;Kupffer cells: 559.7;monocytes: 322.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.4;classical monocyte: 128.4;eosinophil: 75.7;intermediate monocyte: 75.7;myeloid DC: 89.9;neutrophil: 43.7;non-classical monocyte: 72.3" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.7;monocytes: 128.4" "Cell line enhanced" "Detected in all" "RPMI-8226: 1237.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved Vesicles,Microtubules "Secreted to blood" NA NA 520000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Microtubules Vesicles "HPA056390: AB_2683113" "unprognostic (3.25e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-3)" "unprognostic (4.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (2.07e-3)" "unprognostic (8.54e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-3)" "unprognostic (2.99e-1)" "unprognostic (4.63e-2)" "unprognostic (3.78e-3)" "unprognostic (3.16e-1)" 130.5 127.7 37.5 79.0 41.1 125.9 109.7 39.0 45.9 76.8 47.8 77.1 60.3 61.8 109.7 91.7 70.9 128.2 82.2 36.5 40.4 132.1 295.2 99.1 98.9 46.0 39.1 84.2 70.7 75.4 64.8 110.8 44.4 62.9 82.7 80.0 104.5 74.6 71.4 109.8 63.0 77.9 45.7 136.9 61.4 50.1 49.3 35.5 125.8 78.2 63.5 116.3 63.3 61.2 93.5 41.5 21.1 43.5 325.8 89.8 53.0 39.2 17.8 30.7 39.8 67.8 104.4 101.7 112.2 43.6 57.2 143.3 24.3 84.9 20.9 140.3 82.3 41.5 31.1 37.9 111.5 93.6 295.2 94.5 250.5 35.6 38.7 42.7 10.3 35.9 218.5 405.0 42.6 39.2 19.6 95.9 22.8 214.0 63.9 32.5 58.8 1237.2 54.7 64.9 14.0 25.7 98.1 132.8 112.8 70.1 175.5 252.7 19.1 8.0 39.6 126.2 25.9 79.4 168.4 67.7 131.6 96.0 16.3 55.4 128.4 75.7 5.1 75.7 8.0 4.3 7.5 6.5 89.9 2.1 16.6 8.8 43.7 11.0 72.3 6.2 3.9 57.6 37.5 41.1 39.0 45.9 36.5 40.4 46.0 39.1 44.4 45.7 49.3 61.2 44.7 35.3 90.1 5.9 15.3 44.1 49.1 23.1 56.9 17.9 61.7 63.8 55.7 65.8 32.2 55.2 89.6 91.5 18.3 15.6 23.5 36.0 27.6 33.9 19.3 34.2 29.3 124.8 24.7 39.7 41.7 78.4 21.9 64.1 29.9 62.0 48.2 90.3 545.7 15.2 22.1 44.5 14.2 559.7 57.6 27.4 43.5 213.8 24.9 26.2 322.8 30.5 6.2 10.1 14.6 21.0 31.5 28.6 27.8 34.0 46.3 60.6 18.5 31.5 13.1 43.2 40.8 65.5 42.0 86.3 51.1 126.7 17.3 38.9 50.4 44.0 CREG2 ENSG00000175874 "Cellular repressor of E1A stimulated genes 2" Q8IUH2 2 101345550-101387503 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "brain: 27.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 66.0;Inhibitory neurons: 27.6;Oligodendrocytes: 12.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 12 "amygdala: 8.7;basal ganglia: 17.2;cerebral cortex: 26.3;hippocampal formation: 27.8;white matter: 9.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.5;HaCaT: 6.3;HeLa: 2.5;OE19: 7.1;PC-3: 2.4;RT4: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038224 Enhanced "Secreted in brain" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038224: AB_10673167" "unprognostic (5.09e-2)" "unprognostic (3.78e-3)" "unprognostic (4.10e-3)" "unprognostic (8.15e-3)" "unprognostic (5.63e-3)" "unprognostic (9.68e-3)" "unprognostic (4.52e-8)" "unprognostic (3.86e-4)" "unprognostic (1.39e-1)" "unprognostic (6.49e-2)" "unprognostic (1.90e-2)" "unprognostic (7.69e-2)" "unprognostic (5.41e-3)" "unprognostic (4.44e-2)" "unprognostic (2.91e-1)" "unprognostic (8.26e-3)" "unprognostic (7.77e-2)" 0.0 0.1 8.7 0.0 17.2 0.1 0.0 0.0 26.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 27.8 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.2 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.1 0.7 9.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.1 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 8.7 17.2 0.0 26.3 27.8 0.0 1.3 0.0 0.6 0.0 1.4 9.0 0.0 0.0 0.0 2.9 0.0 0.0 0.6 0.5 0.0 0.8 0.1 0.1 0.9 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.2 0.0 0.5 0.0 0.0 66.0 0.2 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 27.6 0.1 2.0 0.0 0.0 6.5 0.0 0.2 0.0 6.5 0.0 0.8 0.0 2.5 12.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.5 0.0 0.2 0.1 1.5 5.6 0.5 0.0 0.1 0.0 0.2 0.0 1.5 CRELD1 "AVSD2, CIRRIN" ENSG00000163703 "Cysteine rich with EGF like domains 1" Q96HD1 3 9933816-9945406 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 110.3;hTERT-RPE1: 77.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026964 Uncertain Approved Nucleoli,Cytosol "Intracellular and membrane" NA NA 19000000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Nucleoli "HPA026964: AB_10602210" "unprognostic (3.06e-2)" "unprognostic (1.08e-1)" "unprognostic (2.69e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.07e-4)" "unprognostic (3.03e-1)" "unprognostic (3.59e-1)" "unprognostic (2.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.19e-1)" "unprognostic (1.92e-2)" "unprognostic (4.59e-2)" "unprognostic (1.14e-2)" "unprognostic (6.31e-2)" "unprognostic (9.51e-2)" "unprognostic (2.89e-1)" "unprognostic (3.78e-2)" 32.7 37.3 63.6 11.4 63.5 9.3 24.8 69.1 94.4 27.7 59.1 57.5 14.0 31.3 17.0 18.0 34.9 16.5 73.2 63.9 65.7 43.0 57.1 27.5 12.4 64.7 63.0 32.5 27.6 22.7 70.9 17.9 66.3 47.6 12.1 16.4 26.3 34.5 48.9 20.1 25.9 22.2 58.6 28.6 35.6 23.6 65.5 10.5 67.6 26.4 9.2 33.6 24.4 68.2 6.4 8.1 19.3 8.8 30.1 17.6 110.3 26.7 8.0 6.1 11.7 11.1 20.7 8.4 57.6 17.7 27.7 4.5 10.4 17.6 4.9 15.2 9.2 7.3 15.2 28.2 68.7 3.3 29.3 21.7 32.3 15.2 13.6 77.2 28.8 11.1 9.5 10.4 6.1 15.5 3.6 19.3 5.7 30.1 6.6 4.8 3.1 21.6 25.9 9.9 6.9 26.7 12.6 10.3 24.3 27.5 27.9 17.0 21.7 12.1 19.5 16.2 6.3 10.7 14.2 15.2 27.3 7.8 13.0 12.3 10.2 9.3 11.9 9.8 12.2 7.9 8.9 11.5 6.9 8.7 11.3 10.4 1.8 13.8 12.9 12.3 7.2 9.5 63.6 63.5 69.1 94.4 63.9 65.7 64.7 63.0 66.3 58.6 65.5 68.2 24.7 19.2 17.5 43.4 14.1 9.7 26.2 48.5 15.9 21.5 17.5 15.0 41.9 31.5 24.0 16.5 16.7 23.7 15.1 10.9 7.9 19.6 6.8 10.3 7.0 20.2 27.0 7.8 38.0 4.4 11.5 20.1 19.4 12.9 21.0 18.8 19.2 14.9 20.6 32.0 37.1 19.1 38.7 8.8 9.0 10.1 32.0 10.0 12.4 15.0 13.9 18.3 27.8 14.6 21.7 8.7 20.4 26.4 15.3 31.4 18.8 11.1 13.2 15.8 26.3 11.0 17.1 68.0 26.5 9.6 12.4 22.2 15.4 11.2 15.4 20.2 CRELD2 MGC11256 ENSG00000184164 "Cysteine rich with EGF like domains 2" Q6UXH1 22 49918167-49927540 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 349.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000603, CAB025604" Approved "Intracellular and membrane" NA NA 480000 "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 55: Plasma cells - Humoral immune response" "CAB025604: , HPA000603: AB_1078565" "unprognostic (1.12e-1)" "unprognostic (7.35e-2)" "unprognostic (1.10e-1)" "prognostic favorable (2.42e-7)" "unprognostic (5.04e-2)" "unprognostic (5.43e-2)" "unprognostic (3.21e-3)" "unprognostic (2.71e-1)" "unprognostic (3.60e-1)" "unprognostic (1.24e-1)" "unprognostic (2.57e-2)" "unprognostic (7.97e-2)" "prognostic unfavorable (1.34e-9)" "unprognostic (6.13e-2)" "unprognostic (3.01e-1)" "unprognostic (7.30e-2)" "unprognostic (4.02e-1)" 29.0 28.5 17.7 25.8 20.6 18.1 24.1 19.3 20.1 25.4 19.2 29.6 26.4 31.5 41.8 26.6 28.2 13.6 33.0 18.3 21.4 26.7 97.8 31.5 19.1 22.1 19.9 23.5 123.3 13.0 65.5 14.4 21.5 27.3 16.4 7.7 39.5 17.1 15.8 17.0 26.8 15.8 19.0 40.3 46.0 43.2 24.9 15.4 67.4 7.6 15.2 27.1 21.3 21.9 37.5 25.5 29.3 96.6 30.6 34.6 39.1 76.4 46.0 41.9 35.5 44.7 44.0 20.4 59.6 66.2 42.3 36.4 37.1 38.3 18.0 11.0 60.1 11.2 37.3 55.8 126.1 44.1 41.4 31.8 33.6 36.4 30.6 29.5 42.9 21.8 16.5 79.5 31.8 119.3 17.2 46.2 21.1 73.9 54.7 41.1 51.9 46.4 20.3 33.6 19.0 53.5 64.9 75.2 32.0 19.3 30.8 51.8 32.7 35.5 59.2 33.1 23.9 65.4 16.9 17.9 52.6 32.5 57.3 33.5 12.4 17.2 17.2 14.9 17.7 29.2 14.9 23.2 13.7 28.1 12.4 10.2 6.4 35.4 8.9 52.2 11.3 12.9 17.7 20.6 19.3 20.1 18.3 21.4 22.1 19.9 21.5 19.0 24.9 21.9 42.4 6.4 16.1 12.7 82.6 32.8 34.4 49.0 10.2 34.7 35.3 34.2 17.7 31.5 39.6 9.2 25.0 32.4 65.6 45.6 7.9 41.2 112.5 28.4 41.5 32.2 39.9 12.4 9.7 63.2 120.5 56.8 50.4 37.0 36.2 27.0 47.2 63.9 74.6 25.2 10.9 136.3 26.4 25.7 47.0 25.8 44.1 33.8 96.0 6.5 27.8 41.7 80.3 9.5 16.2 51.2 35.1 41.3 349.6 82.4 28.2 16.6 37.4 32.0 13.1 25.7 39.7 143.5 104.8 21.6 30.7 55.1 53.0 41.0 55.7 43.8 CRH "CRF, CRH1" ENSG00000147571 "Corticotropin releasing hormone" P06850 8 66176376-66178464 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "brain: 137.2" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 160.6" "Cancer enriched" "Detected in some" 28 "urothelial cancer: 34.5" "Region enriched" "Detected in many" 6 "medulla oblongata: 137.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "pons: 25.1" "Secreted to blood" NA NA 10000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.62e-1)" "unprognostic (9.68e-2)" "unprognostic (1.00e-1)" "unprognostic (9.55e-2)" "unprognostic (7.22e-3)" 1.5 0.2 5.6 0.0 2.2 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 9.6 0.0 0.0 0.0 0.0 137.2 9.8 0.0 1.6 0.7 0.2 6.6 16.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.8 23.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 2.2 0.0 5.4 1.3 9.6 137.2 9.8 16.9 0.2 23.0 1.5 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 31.5 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.0 160.6 0.0 0.0 0.0 0.1 CRHBP "CRF-BP, CRFBP" ENSG00000145708 "Corticotropin releasing hormone binding protein" P24387 5 76953045-76981158 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 166.5" "Group enriched" "Detected in some" 6 "Granulosa cells: 480.8;Hepatic stellate cells: 1319.7" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 4.4;BJ hTERT+ SV40 Large T+ RasG12V: 4.4;HBF TERT88: 7.7;hTEC/SVTERT24-B: 2.6;RPMI-8226: 2.5;U-698: 7.6;U-87 MG: 4.3;WM-115: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036234, HPA046120" Approved Supported "Secreted to blood" NA NA 69000000 "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA036234: , HPA046120: AB_10959760" "unprognostic (1.41e-1)" "unprognostic (2.00e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.36e-3)" "unprognostic (4.44e-5)" "unprognostic (2.16e-1)" "unprognostic (7.08e-2)" "unprognostic (4.98e-4)" "unprognostic (1.09e-1)" "unprognostic (6.63e-5)" "unprognostic (2.76e-2)" "unprognostic (4.64e-1)" "unprognostic (1.74e-1)" "unprognostic (2.95e-2)" 22.2 13.7 4.1 0.7 5.6 3.2 6.2 3.2 7.5 3.7 2.2 0.4 0.6 2.6 0.9 0.2 1.8 0.8 7.4 5.8 15.8 36.5 166.5 0.5 0.9 7.0 9.1 1.3 0.1 0.6 0.1 10.2 11.9 1.1 0.4 0.1 1.1 4.1 0.9 0.5 0.7 1.5 3.7 37.2 0.3 0.8 20.1 0.5 4.1 1.3 0.6 0.9 0.8 7.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 4.4 4.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 7.6 4.3 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 4.1 5.6 3.2 7.5 5.8 15.8 7.0 9.1 11.9 3.7 20.1 7.0 134.9 0.0 0.0 1.3 8.8 0.4 0.0 0.0 0.0 0.0 0.4 1.1 0.7 17.2 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 45.9 0.0 39.4 0.8 0.2 0.2 0.3 0.0 0.0 0.0 480.8 1319.7 9.9 1.8 0.0 32.4 0.0 0.0 75.0 2.1 1.0 0.3 3.8 0.0 4.7 0.3 0.0 0.0 0.5 11.1 0.0 0.0 0.0 0.9 0.0 0.0 3.6 0.0 0.0 0.0 0.1 2.3 0.5 1.9 0.1 0.0 0.0 1.7 0.0 0.0 0.1 CRHR1 "CRF-R, CRF1, CRHR" ENSG00000120088 "Corticotropin releasing hormone receptor 1" P34998 17 45784280-45835828 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.4;pituitary gland: 22.6" "Group enriched" "Detected in some" 4 "Early spermatids: 41.0;Late spermatids: 53.4" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebellum: 10.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RT4: 3.4;SH-SY5Y: 1.8" CAB025251 Enhanced "Intracellular and membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "CAB025251: " "unprognostic (4.59e-2)" "unprognostic (1.43e-2)" "unprognostic (2.59e-7)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (3.94e-2)" "unprognostic (2.48e-1)" "unprognostic (4.55e-4)" "unprognostic (1.65e-2)" "unprognostic (2.21e-1)" "unprognostic (3.33e-4)" "unprognostic (2.07e-5)" "unprognostic (3.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.59e-1)" 0.2 0.0 4.1 0.0 1.7 0.0 0.4 10.4 4.8 2.3 0.0 0.0 0.0 1.1 0.1 0.1 0.7 0.0 0.0 1.9 0.4 0.1 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.1 22.6 0.0 0.2 0.6 0.0 3.5 0.2 0.3 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.2 2.8 0.0 0.2 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 1.7 10.4 4.8 1.9 0.4 0.0 1.5 0.2 0.0 2.8 0.0 0.0 0.0 0.0 0.0 2.8 1.1 1.3 1.2 10.2 0.7 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 41.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.0 1.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 53.4 0.6 0.3 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.1 0.4 3.2 1.6 0.1 0.1 0.4 0.5 0.0 0.5 1.6 5.1 1.5 9.9 3.3 0.0 2.5 0.0 0.1 1.7 CRHR2 "CRF-RB, CRF2, HM-CRF" ENSG00000106113 "Corticotropin releasing hormone receptor 2" Q13324 7 30651942-30700129 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.0;choroid plexus: 21.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.0;Excitatory neurons: 8.2;Horizontal cells: 13.5;Inhibitory neurons: 4.9;Smooth muscle cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Low region specificity" "Detected in many" HPA073345 Supported "Plasma membrane" "Secreted - unknown location" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA073345: " "unprognostic (7.14e-2)" "unprognostic (4.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.24e-3)" "unprognostic (5.69e-2)" "unprognostic (8.58e-2)" "unprognostic (6.00e-2)" "unprognostic (1.86e-4)" "unprognostic (2.01e-1)" "unprognostic (3.07e-1)" "unprognostic (5.90e-4)" "unprognostic (4.02e-2)" "unprognostic (8.29e-4)" "unprognostic (3.73e-3)" "unprognostic (2.84e-3)" "unprognostic (1.81e-1)" "unprognostic (3.84e-1)" 0.6 0.0 1.5 0.0 1.0 0.0 0.6 0.4 6.0 0.3 21.7 0.2 0.3 0.3 0.0 0.2 0.5 0.1 2.1 2.3 1.0 0.8 0.0 0.1 0.0 1.4 1.0 0.4 1.7 0.1 4.2 0.0 0.4 0.2 0.1 2.5 0.3 1.3 1.2 0.2 0.3 0.1 0.4 0.0 0.2 0.8 2.8 0.0 0.7 2.2 0.0 0.3 0.2 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.4 6.0 2.3 1.0 1.4 1.0 0.4 0.4 2.8 2.4 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 4.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CRISP1 "AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP" ENSG00000124812 "Cysteine rich secretory protein 1" P54107 6 49834257-49877096 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "epididymis: 1573.9" "Group enriched" "Detected in some" 29 "Early spermatids: 45.5;Late spermatids: 71.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.0;NB-4: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA028445, HPA030534" Enhanced "Secreted in male reproductive system" NA NA 35000 "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA028445: AB_10670428, HPA030534: AB_2732459" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1573.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 66.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.5 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 71.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CRISP2 "CRISP-2, CT36, GAPDL5, TPX1" ENSG00000124490 "Cysteine rich secretory protein 2" P16562 6 49692358-49713590 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "testis: 505.0" "Group enriched" "Detected in some" 33 "Early spermatids: 5765.5;Late spermatids: 21517.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031248 Enhanced "Secreted in male reproductive system" NA NA 820000 "Cluster 83: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA031248: AB_10602211" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (7.38e-2)" "unprognostic (2.35e-2)" "unprognostic (9.23e-3)" "unprognostic (4.05e-2)" 0.1 0.0 0.0 0.0 0.0 16.6 0.5 0.0 0.0 1.9 0.7 0.0 0.1 0.2 0.9 3.6 17.6 7.7 0.1 0.0 0.2 0.8 0.2 1.2 0.0 0.1 0.1 0.1 0.6 0.0 2.0 0.0 0.0 1.2 0.0 0.1 15.6 2.5 0.2 0.5 0.3 0.0 0.0 0.5 0.1 505.0 0.1 0.0 0.2 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 0.1 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5765.5 17.8 0.5 6.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 21517.6 133.9 6.1 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 83.8 0.0 2.8 0.2 0.1 24.1 0.0 65.7 0.0 0.0 409.8 65.1 0.0 0.0 0.0 0.0 0.0 0.3 2.3 CRISP3 "Aeg2, CRISP-3, CRS3, dJ442L6.3, SGP28" ENSG00000096006 "Cysteine rich secretory protein 3" P54108 6 49727376-49744437 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 1203.8;salivary gland: 2310.0" "Group enriched" "Detected in some" 7 "Endometrial ciliated cells: 182.2;Glandular and luminal cells: 551.5" "Group enriched" "Detected in many" 7 "breast cancer: 31.9;pancreatic cancer: 59.8;prostate cancer: 85.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "neutrophil: 2.5;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 19 "granulocytes: 2.5;monocytes: 1.2" "Group enriched" "Detected in some" 20 "HEL: 12.3;RT4: 4.1;SK-BR-3: 9.3;T-47d: 4.4" "Not detected" "Not detected" HPA054392 Supported "Secreted in other tissues" NA NA 420000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 36: HEL - Hemostasis" "Cluster 44: Endometrium - Transcription" "HPA054392: AB_2682472" "unprognostic (1.28e-2)" "unprognostic (7.01e-2)" "unprognostic (8.93e-2)" "unprognostic (5.56e-2)" "unprognostic (1.02e-1)" "unprognostic (2.22e-4)" "unprognostic (5.30e-2)" "unprognostic (6.70e-2)" "unprognostic (9.16e-2)" "unprognostic (4.34e-3)" "unprognostic (1.91e-1)" "unprognostic (1.93e-1)" 0.3 0.6 0.0 0.0 0.0 381.8 3.9 0.0 0.0 61.0 0.0 0.1 0.4 1.7 0.1 266.8 1203.8 23.1 0.8 0.0 0.0 0.1 0.9 1.3 0.0 0.0 0.0 0.5 5.5 0.0 0.5 0.6 0.0 2.9 0.0 0.0 2310.0 111.9 0.3 3.9 0.2 0.0 0.0 2.5 0.3 0.2 0.0 0.3 0.2 0.0 4.0 4.7 140.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 9.3 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.0 0.0 2.1 5.6 0.0 21.5 13.1 3.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 182.2 47.2 0.8 0.0 0.4 0.0 3.7 0.0 0.2 0.0 551.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 26.8 CRISPLD1 "Cocoacrisp, DKFZp762F133, LCRISP1" ENSG00000121005 "Cysteine rich secretory protein LCCL domain containing 1" Q9H336 8 74984505-75034558 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 29.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 36.1;Endometrial ciliated cells: 62.2;Oligodendrocyte precursor cells: 81.4" "Cancer enhanced" "Detected in many" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 134.4;SH-SY5Y: 72.0;SuSa: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024725 Uncertain "Secreted - unknown location" NA NA 8200 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA024725: AB_1847238" "unprognostic (2.16e-1)" "unprognostic (5.88e-2)" "unprognostic (4.01e-2)" "unprognostic (3.78e-2)" "unprognostic (3.85e-2)" "unprognostic (1.65e-1)" "unprognostic (2.09e-4)" "unprognostic (6.81e-2)" "unprognostic (1.58e-2)" "unprognostic (5.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (7.39e-3)" "unprognostic (2.38e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" 2.7 1.3 3.9 2.5 4.0 1.5 29.4 3.4 3.1 6.3 3.4 2.7 0.7 8.6 4.9 5.0 7.4 10.0 8.8 4.3 8.0 2.1 2.1 2.3 2.8 5.8 10.4 5.7 2.4 19.3 1.2 7.8 8.3 24.6 1.6 3.1 19.3 2.6 0.5 2.3 1.2 7.0 6.3 2.0 0.9 3.8 4.1 9.4 15.1 1.2 1.1 2.5 1.1 10.7 0.0 1.7 134.4 0.0 0.0 0.0 4.5 0.0 0.0 1.6 1.9 0.8 0.0 0.0 19.0 0.0 2.2 0.1 11.3 0.1 0.0 0.1 5.2 0.2 5.1 0.0 3.0 0.0 1.0 7.2 0.3 0.1 1.0 16.6 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.2 13.9 0.0 5.0 0.0 18.5 0.2 0.0 0.0 0.8 72.0 0.0 0.1 8.0 27.5 10.4 6.4 0.0 3.8 19.6 0.2 0.5 2.4 0.9 0.0 4.6 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.9 4.0 3.4 3.1 4.3 8.0 5.8 10.4 8.3 6.3 4.1 10.7 1.0 3.2 0.0 12.7 0.0 0.8 6.1 1.4 17.6 1.6 10.3 36.1 0.4 0.0 5.4 1.8 0.0 22.7 0.3 0.0 0.0 0.0 15.3 62.2 4.9 3.2 0.0 3.0 15.7 0.0 3.8 9.2 0.0 22.4 3.8 1.8 23.6 0.1 2.0 0.0 11.1 0.0 0.0 0.9 0.0 1.5 4.1 0.4 7.2 1.9 0.0 8.8 0.0 81.4 0.9 0.0 0.0 1.5 0.0 9.4 0.0 0.2 22.5 0.9 0.0 0.4 1.5 1.3 6.0 2.5 1.0 12.0 0.4 6.3 0.0 2.3 CRISPLD2 "DKFZP434B044, LCRISP2, LGL1" ENSG00000103196 "Cysteine rich secretory protein LCCL domain containing 2" Q9H0B8 16 84819985-84920768 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 137.3;Fibroblasts: 185.5;Leydig cells: 271.5;Peritubular cells: 265.9;Skeletal myocytes: 146.2;Smooth muscle cells: 341.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 87.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 87.2" "Cell line enhanced" "Detected in many" "ASC diff: 43.7;BEWO: 69.2;HHSteC: 161.4;HSkMC: 68.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 15.6" "HPA030054, HPA030055" Approved Approved Nucleoplasm,Nucleoli "Secreted to blood" No No 219000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Nucleoli" "HPA030054: AB_2732452, HPA030055: AB_10611821" "unprognostic (8.91e-3)" "unprognostic (3.05e-1)" "unprognostic (2.63e-2)" "unprognostic (2.02e-2)" "unprognostic (7.12e-2)" "unprognostic (2.30e-1)" "unprognostic (2.11e-2)" "unprognostic (5.58e-3)" "unprognostic (1.48e-1)" "unprognostic (5.50e-2)" "unprognostic (2.67e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (1.97e-6)" "unprognostic (7.35e-3)" "unprognostic (3.38e-2)" "unprognostic (2.99e-3)" "unprognostic (5.15e-3)" 113.4 29.0 3.3 46.6 4.9 8.1 64.2 3.9 4.6 112.9 2.6 88.9 10.8 115.7 20.3 39.9 129.0 104.0 36.6 3.7 5.2 40.9 17.1 92.7 7.3 5.9 5.5 80.7 23.5 2.5 19.3 122.7 5.9 98.9 18.1 2.4 18.1 27.7 15.0 36.7 58.5 95.0 4.4 24.9 65.9 21.5 4.3 8.2 47.9 12.2 3.7 119.9 69.8 5.7 0.9 2.2 0.6 6.0 43.7 16.2 69.2 34.5 30.4 27.2 19.1 4.7 2.9 0.1 3.0 30.5 8.0 1.0 0.1 0.1 27.3 0.0 0.2 0.5 0.9 0.1 161.4 0.0 0.3 68.0 0.1 8.0 0.1 9.0 0.2 0.0 0.3 0.3 3.1 1.4 0.3 1.7 2.0 4.6 2.0 0.1 0.3 0.4 0.2 5.5 6.7 0.5 8.1 3.5 0.7 9.4 13.7 0.9 3.8 0.4 1.8 28.3 1.0 0.4 0.1 5.8 0.2 0.5 4.1 14.8 20.2 0.7 0.0 1.2 0.0 0.1 0.2 0.0 1.3 0.0 0.1 0.0 87.2 0.0 0.0 0.1 0.0 4.2 3.3 4.9 3.9 4.6 3.7 5.2 5.9 5.5 5.9 4.4 4.3 5.7 5.9 3.2 2.3 0.7 0.7 46.1 8.6 0.6 9.6 0.5 3.9 7.6 8.6 2.8 1.6 0.0 0.0 7.4 0.8 1.8 0.0 1.4 12.6 7.0 137.3 21.7 3.0 0.0 2.2 0.5 42.4 185.5 27.0 6.3 7.0 11.5 38.6 0.8 4.7 1.7 1.5 4.1 0.0 36.6 39.6 19.6 271.5 14.8 48.0 9.4 41.5 5.1 3.1 54.3 0.6 0.9 0.3 265.9 0.9 17.1 0.2 0.1 0.9 0.7 92.1 146.2 341.2 1.0 1.9 3.7 42.8 9.0 5.4 5.7 2.2 6.5 CRLF1 "CISS, CISS1, CLF, CLF-1" ENSG00000006016 "Cytokine receptor like factor 1" O75462 19 18572220-18607741 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 88.5" "Cell type enhanced" "Detected in some" "Astrocytes: 15.3;Basal keratinocytes: 9.7;Fibroblasts: 16.0;Respiratory ciliated cells: 11.9;Skeletal myocytes: 19.9;Smooth muscle cells: 10.5" "Group enriched" "Detected in all" 4 "lung cancer: 27.4;thyroid cancer: 36.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "ASC diff: 1048.7;Hep G2: 458.8" "Region enriched" "Detected in many" 7 "hippocampal formation: 21.1" "Group enriched" "Detected in some" 6 "cerebellum: 2.3;spinal cord: 8.6" "HPA041493, HPA041793" Approved "Secreted in other tissues" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041493: AB_10795637, HPA041793: AB_10804117" "unprognostic (1.97e-1)" "unprognostic (2.29e-1)" "unprognostic (2.34e-3)" "unprognostic (9.31e-3)" "unprognostic (1.58e-2)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (4.69e-2)" "unprognostic (3.34e-3)" "unprognostic (4.95e-2)" "unprognostic (7.92e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.86e-2)" "unprognostic (5.27e-3)" 40.1 14.5 18.7 0.9 24.6 0.0 18.7 22.4 51.7 25.7 11.2 8.9 0.5 12.8 0.9 17.4 11.3 1.4 88.5 22.0 13.5 7.7 1.5 16.0 0.4 24.3 28.0 4.5 8.9 0.5 8.9 11.3 17.8 8.9 0.4 0.1 14.9 6.2 21.4 27.3 5.0 1.5 18.7 2.4 7.5 1.3 13.4 0.3 50.3 0.9 0.2 9.3 15.5 25.5 0.0 0.0 0.0 10.7 1048.7 15.3 5.2 5.4 0.0 0.0 0.0 0.1 0.0 0.0 66.5 33.2 1.9 0.4 10.8 0.2 0.0 0.0 1.4 0.0 18.1 458.8 7.5 0.1 0.5 12.0 1.0 0.2 0.3 1.6 0.3 0.0 0.1 0.2 0.3 16.6 0.0 0.0 1.2 0.1 0.3 0.0 9.1 0.1 0.0 0.5 0.0 0.1 14.2 0.0 0.0 2.0 13.0 0.6 1.3 0.1 11.1 0.8 0.4 0.1 0.0 0.5 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 24.6 22.4 51.7 22.0 13.5 24.3 28.0 17.8 18.7 13.4 25.5 0.4 0.0 0.0 15.3 0.3 9.7 0.6 6.8 0.0 0.2 0.7 4.2 2.5 0.0 2.6 0.0 0.0 0.1 0.3 0.1 5.9 0.3 6.9 2.6 1.9 0.5 0.0 0.0 7.8 0.2 1.3 16.0 0.5 0.5 0.0 0.2 0.4 0.1 0.3 0.0 1.0 0.0 2.0 0.0 1.0 0.4 0.0 0.4 0.0 0.0 0.1 0.9 1.0 0.5 0.8 0.2 0.0 0.0 0.0 0.3 0.0 0.3 11.9 1.3 0.0 19.9 10.5 0.2 2.2 0.6 4.5 0.3 0.6 0.2 0.1 0.3 CRP PTX1 ENSG00000132693 "C-reactive protein" P02741 1 159712289-159714589 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 79 "liver: 9388.5" "Group enriched" "Detected in some" 16 "Ductal cells: 1087.7;Hepatocytes: 4142.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 1010.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;HDLM-2: 6.3;U-2 OS: 4.5;U-266/84: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005036, HPA027367, HPA027396" Supported Approved "Nucleoplasm,Vesicles,Intermediate filaments" "Secreted to blood" NA NA 2920000000 5200000000 "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB005036: AB_562362, HPA027367: AB_1847216, HPA027396: AB_1847217" "unprognostic (3.74e-1)" "unprognostic (5.31e-2)" "unprognostic (2.97e-2)" "unprognostic (1.27e-1)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (4.17e-10)" "unprognostic (3.39e-2)" "unprognostic (3.48e-1)" "unprognostic (5.60e-2)" "unprognostic (6.61e-2)" 3.4 0.7 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.3 0.0 3.1 0.0 0.5 0.4 111.7 0.7 0.0 0.0 0.7 9388.5 0.5 0.1 0.0 0.0 0.4 118.5 0.0 0.3 0.1 0.0 0.6 0.0 0.0 0.4 0.0 0.3 0.6 0.5 0.0 0.0 6.1 0.4 0.4 0.0 0.0 0.3 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 6.3 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.8 0.0 11.7 1.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 118.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1087.7 1.4 0.0 0.1 6.3 0.0 163.2 0.0 63.2 0.0 0.0 0.0 0.2 0.0 0.0 89.6 4142.7 0.1 0.0 0.0 0.0 0.0 98.8 0.3 0.7 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 60.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 CRTAC1 "ASPIC1, CEP-68, FLJ10320" ENSG00000095713 "Cartilage acidic protein 1" Q9NQ79 10 97865000-98030828 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.6;fallopian tube: 38.2;lung: 50.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 119.5;Club cells: 36.4;Inhibitory neurons: 63.6;Oligodendrocyte precursor cells: 54.8" "Cancer enhanced" "Detected in many" "melanoma: 43.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 3.0;HMC-1: 2.5;HUVEC TERT2: 7.1;SCLC-21H: 4.7;SK-MEL-30: 7.7;TIME: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008175 Enhanced "Secreted to extracellular matrix" NA NA 550000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "HPA008175: AB_1847254" "unprognostic (2.55e-1)" "unprognostic (6.41e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.54e-1)" "unprognostic (6.96e-3)" "unprognostic (9.30e-2)" "unprognostic (9.13e-2)" "unprognostic (1.02e-2)" "unprognostic (3.01e-1)" "unprognostic (7.66e-2)" "unprognostic (1.69e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.70e-4)" "unprognostic (1.05e-2)" "unprognostic (3.29e-3)" "prognostic favorable (1.51e-4)" 4.4 0.8 8.7 1.1 23.7 0.0 2.4 10.9 20.1 6.4 0.9 11.5 0.5 1.3 3.8 8.3 38.2 0.3 10.6 9.1 8.1 4.3 0.4 50.0 0.4 45.1 10.2 0.7 1.3 0.8 5.3 0.0 45.6 2.3 0.4 11.3 3.4 33.6 1.1 4.1 2.3 0.8 12.6 0.1 1.8 3.9 18.5 0.2 4.7 1.5 0.3 30.2 4.9 15.5 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.7 0.0 3.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 4.7 1.1 0.5 0.0 7.7 0.3 0.0 0.0 9.4 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 23.7 10.9 20.1 9.1 8.1 45.1 10.2 45.6 12.6 18.5 15.5 1.9 22.4 119.5 2.9 0.0 1.5 2.7 1.3 5.7 10.1 2.6 2.8 7.1 1.5 36.4 9.2 0.0 0.0 0.1 0.0 0.0 4.6 0.1 0.5 0.1 8.8 1.8 0.0 22.9 0.7 0.0 2.3 0.0 0.6 5.1 0.0 5.7 0.1 0.0 0.0 63.6 0.0 0.0 0.6 0.9 0.6 0.0 0.2 8.8 2.8 0.0 14.1 0.0 54.8 6.2 0.6 0.0 0.4 1.2 1.3 0.0 0.0 0.9 5.3 0.0 3.5 0.3 1.5 1.9 13.1 0.4 0.0 0.4 0.0 0.0 1.7 CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.6" "Group enriched" "Detected in all" 5 "dendritic cells: 306.9;monocytes: 377.6" "Cell line enhanced" "Detected in all" "ASC diff: 795.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: AB_10960991, HPA044150: AB_10959594" "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.85e-3)" "unprognostic (7.36e-2)" "unprognostic (4.73e-3)" "unprognostic (4.28e-2)" "unprognostic (1.87e-1)" "unprognostic (9.97e-2)" "unprognostic (4.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (9.93e-2)" "unprognostic (1.28e-3)" 157.2 106.5 65.2 38.7 69.2 43.2 123.9 51.9 54.8 211.2 52.9 145.1 35.0 170.1 57.1 58.7 138.3 80.5 83.9 49.6 64.9 67.9 44.6 92.3 37.3 65.2 62.4 131.4 36.0 45.7 22.8 69.9 63.9 90.7 51.6 19.3 54.0 106.5 54.4 84.1 65.6 115.0 67.5 48.2 78.9 25.0 65.3 23.7 77.2 68.9 38.1 142.7 135.8 69.5 64.1 123.3 37.8 119.2 795.0 516.6 219.0 136.1 294.0 160.6 151.9 42.1 35.1 44.4 147.6 259.3 129.9 80.2 68.0 103.9 115.5 110.1 106.0 69.2 87.6 43.7 237.4 45.4 54.8 415.3 208.5 145.0 183.2 311.7 172.0 27.0 60.3 82.1 164.6 54.7 16.5 46.3 45.5 67.5 165.7 59.4 111.0 86.1 127.8 42.0 7.9 61.0 92.0 79.8 201.1 87.3 85.9 109.3 113.0 209.1 89.1 115.4 145.9 59.0 214.3 6.7 164.3 89.7 117.1 13.4 377.6 28.5 35.8 147.7 52.5 39.9 51.4 40.2 306.9 39.2 29.2 27.8 30.5 42.1 46.0 82.5 74.0 200.5 65.2 69.2 51.9 54.8 49.6 64.9 65.2 62.4 63.9 67.5 65.3 69.5 74.0 9.6 42.8 15.3 29.0 60.4 41.1 39.5 150.8 17.9 32.7 43.7 34.7 25.8 22.0 38.6 8.4 49.0 37.1 14.8 11.7 25.0 1.2 17.4 135.7 72.7 6.0 46.0 10.0 32.0 81.6 142.3 29.0 31.2 48.1 58.4 122.4 53.2 107.0 35.3 14.5 26.0 10.2 181.1 91.1 6.3 142.9 108.6 80.0 10.3 134.1 15.9 22.6 17.1 11.6 18.4 16.3 144.8 58.1 24.5 24.4 52.7 6.8 10.1 111.7 78.4 120.9 1.6 15.9 95.1 46.7 28.0 26.5 89.9 36.1 30.0 CRY2 ENSG00000121671 "Cryptochrome circadian regulator 2" Q49AN0 11 45847118-45883248 "Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 141.9;Horizontal cells: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037577 Supported Supported "Nuclear speckles,Cytosol" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Nuclear speckles" Cytosol "HPA037577: AB_10672497" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (1.31e-2)" "unprognostic (9.16e-2)" "unprognostic (3.09e-2)" "prognostic favorable (6.82e-5)" "unprognostic (1.48e-3)" "unprognostic (1.67e-1)" "unprognostic (5.07e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.01e-1)" "prognostic favorable (6.44e-15)" "unprognostic (8.13e-3)" "unprognostic (1.89e-1)" "unprognostic (4.24e-2)" "unprognostic (2.24e-1)" 31.8 22.3 33.3 8.9 35.3 29.4 27.1 36.4 36.9 24.4 22.8 26.5 10.8 23.3 16.9 15.9 29.1 17.4 60.0 36.6 29.3 22.5 62.7 22.9 10.4 27.4 31.5 38.7 34.7 22.4 30.8 13.5 28.5 25.3 9.9 52.8 21.7 22.1 96.7 50.4 16.7 17.1 28.8 14.0 24.6 34.4 35.2 12.6 34.0 64.8 10.3 26.0 18.4 31.4 1.4 4.2 6.3 7.5 16.7 8.4 13.8 5.0 8.9 6.2 4.5 6.8 3.3 9.8 3.8 10.5 5.9 8.5 6.0 5.2 4.3 9.8 5.5 6.4 8.2 9.4 6.4 8.0 8.5 9.9 7.5 4.8 7.6 7.0 4.4 7.5 12.7 16.2 5.6 5.3 6.8 9.4 17.1 17.8 5.0 11.5 9.1 4.6 4.5 7.8 10.1 3.8 8.3 7.5 4.5 8.0 10.0 5.5 5.5 8.7 5.3 13.5 3.6 15.0 10.8 7.9 5.3 3.5 5.3 4.1 3.5 5.4 5.7 4.8 4.7 5.0 5.5 6.1 3.6 4.6 6.6 6.9 1.8 7.5 8.0 2.6 4.9 5.3 33.3 35.3 36.4 36.9 36.6 29.3 27.4 31.5 28.5 28.8 35.2 31.4 11.7 12.8 18.2 48.0 12.6 17.0 9.7 5.1 8.0 141.9 10.6 8.6 34.7 14.3 11.6 7.3 27.1 8.0 10.0 17.2 29.4 5.4 24.2 28.1 7.5 9.2 7.1 3.0 30.3 4.7 5.6 19.8 12.8 15.4 14.7 10.8 8.6 47.3 3.6 101.0 26.0 7.4 6.1 8.5 12.5 8.7 31.4 7.2 16.0 10.3 6.2 34.4 10.3 13.0 13.6 6.0 6.0 39.9 8.5 11.6 10.5 11.6 23.8 27.5 19.7 14.5 14.6 29.1 15.0 4.4 17.5 9.3 9.1 8.4 6.0 9.8 CSDE1 "D1S155E, UNR" ENSG00000009307 "Cold shock domain containing E1" O75534 1 114716913-114758676 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1408.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 2403.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018846, HPA052221" Supported Enhanced "Plasma membrane,Cytosol" NA NA 100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA018846: AB_1847266, HPA052221: AB_2681767" "unprognostic (2.84e-1)" "unprognostic (9.18e-3)" "unprognostic (4.86e-3)" "unprognostic (3.30e-3)" "unprognostic (2.83e-2)" "unprognostic (4.51e-2)" "unprognostic (5.32e-3)" "unprognostic (5.16e-2)" "unprognostic (1.78e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (2.40e-1)" "unprognostic (4.69e-2)" "unprognostic (4.67e-2)" "unprognostic (1.18e-1)" "unprognostic (5.17e-3)" "unprognostic (2.54e-2)" 412.5 166.8 149.0 170.9 168.8 276.4 241.9 160.5 170.8 193.8 163.5 300.1 187.3 226.7 196.2 247.2 162.9 172.0 414.8 137.6 169.8 228.2 233.6 182.8 172.4 166.4 169.5 258.8 216.2 273.8 85.8 182.4 172.6 229.8 199.6 177.6 230.0 245.6 1408.6 201.6 196.1 236.4 172.2 176.5 201.7 257.4 164.7 218.8 262.6 1039.4 208.2 238.4 137.0 187.3 658.8 226.6 395.5 396.1 440.7 561.4 550.1 566.7 420.5 373.0 301.1 334.0 193.7 514.9 465.6 543.1 217.0 272.3 442.4 439.6 539.2 632.1 302.8 506.1 390.3 299.9 388.2 380.7 288.7 414.7 468.2 447.0 583.2 502.2 433.5 426.5 523.3 327.3 458.9 2403.4 513.8 242.0 755.0 274.0 302.5 378.4 1221.9 244.0 295.4 508.4 485.6 320.7 553.9 455.8 433.3 411.9 234.5 599.4 526.9 437.8 597.3 579.6 629.1 495.7 587.9 567.7 564.9 422.2 1365.1 217.2 241.4 230.8 146.4 233.1 199.7 161.6 186.5 180.7 226.8 130.4 219.3 189.1 155.2 191.0 270.8 87.2 222.2 389.4 149.0 168.8 160.5 170.8 137.6 169.8 166.4 169.5 172.6 172.2 164.7 187.3 193.2 198.7 194.2 41.8 198.3 216.2 219.7 149.0 235.6 134.0 218.2 161.5 572.0 160.2 181.1 128.8 58.4 172.4 155.2 160.8 226.9 198.2 405.5 130.4 178.8 191.3 219.9 232.8 70.8 202.9 208.2 181.7 143.2 174.3 219.1 234.7 156.4 189.1 156.8 99.3 73.7 220.3 120.1 277.9 202.0 639.7 161.8 216.8 220.5 55.3 241.8 195.5 117.4 54.3 86.5 213.8 150.6 225.7 283.6 269.0 240.1 235.5 143.2 121.3 164.3 232.4 274.2 263.3 189.8 247.2 234.0 272.9 193.3 208.2 210.5 283.8 CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 58.9;granulocytes: 113.5;Hepatic stellate cells: 53.2;Sertoli cells: 59.2;Skeletal myocytes: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Cell line enhanced" "Detected in many" "ASC diff: 220.0;BJ hTERT+: 149.5;GAMG: 142.1;HHSteC: 338.7;HSkMC: 216.4;hTERT-RPE1: 153.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" NA NA 270000 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies" "HPA076624: AB_2686810" "unprognostic (2.35e-3)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.19e-1)" "unprognostic (3.60e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.04e-1)" "unprognostic (1.75e-2)" "unprognostic (2.18e-1)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (1.00e-11)" "unprognostic (2.03e-1)" "unprognostic (1.88e-2)" "unprognostic (4.01e-1)" "unprognostic (3.16e-2)" 67.4 37.5 27.5 24.5 32.9 18.4 46.4 36.9 25.8 25.0 32.9 26.8 13.3 21.1 5.2 15.6 28.5 31.9 29.0 24.5 30.9 17.3 16.4 47.6 28.2 42.3 32.6 22.1 17.5 10.5 8.7 41.2 36.1 21.4 16.2 1.5 18.9 16.6 11.4 19.4 26.7 17.6 36.0 48.0 22.0 3.7 32.2 13.5 22.2 11.3 12.2 42.0 29.6 46.5 9.3 29.3 14.7 5.7 220.0 138.3 5.7 36.0 149.5 25.9 23.9 1.3 4.5 0.2 47.0 80.1 142.1 6.8 5.7 11.0 9.4 99.5 5.3 10.9 17.3 10.3 338.7 0.0 13.7 216.4 3.2 57.5 33.0 153.1 5.4 2.8 2.9 5.5 31.2 0.5 0.3 1.8 5.3 2.4 3.1 1.0 8.4 0.9 10.9 7.9 0.5 1.6 9.7 2.6 12.6 16.7 2.3 1.0 19.2 27.8 10.5 123.7 22.1 2.8 1.1 0.3 70.7 0.1 106.6 13.2 0.0 22.3 0.3 0.0 0.6 0.0 0.9 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.3 0.2 27.5 32.9 36.9 25.8 24.5 30.9 42.3 32.6 36.1 36.0 32.2 46.5 30.6 9.6 35.5 11.8 2.3 7.4 5.1 7.9 13.1 0.3 10.0 9.3 3.2 14.3 5.3 3.7 0.0 0.8 2.0 0.6 0.0 40.4 0.4 20.6 9.3 21.6 7.8 11.1 0.3 2.3 0.5 58.9 4.6 24.8 113.5 0.3 53.2 3.0 9.2 0.0 1.0 0.8 0.0 3.5 13.1 0.3 25.1 8.2 10.6 28.1 1.6 1.8 0.0 3.0 17.5 9.3 1.6 8.6 1.9 8.0 1.2 0.9 1.1 0.2 59.2 94.4 37.1 0.6 0.7 5.6 5.5 0.8 20.9 0.7 1.0 2.6 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CSF2 "GM-CSF, GMCSF" ENSG00000164400 "Colony stimulating factor 2" P04141 5 132073789-132076170 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lung: 2.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 11.4;Basal respiratory cells: 11.3;dendritic cells: 17.7;Ductal cells: 18.3;Pancreatic endocrine cells: 24.9;T-cells: 28.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "NK-cell: 6.2" "Lineage enriched" "Detected in single" 12 "NK-cells: 6.2" "Cell line enriched" "Detected in some" 4 "BJ hTERT+: 91.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA057404, HPA062006" Enhanced Vesicles "Secreted to blood" NA NA 23900 "Cluster 15: NK-cells - Transcription" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA057404: AB_2683428, HPA062006: AB_2684654" "unprognostic (7.29e-2)" "unprognostic (2.49e-3)" "unprognostic (8.77e-2)" "unprognostic (2.09e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" "unprognostic (2.56e-1)" "unprognostic (1.47e-2)" "unprognostic (2.64e-1)" "unprognostic (3.68e-3)" "unprognostic (1.87e-8)" "unprognostic (4.81e-2)" "unprognostic (1.22e-1)" "unprognostic (9.07e-2)" "unprognostic (2.06e-2)" 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 2.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 9.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 91.3 0.1 5.1 0.0 7.4 0.0 1.5 0.0 5.3 0.2 0.0 6.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 20.8 13.8 2.5 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.3 3.8 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.2 11.4 0.0 0.3 1.5 0.1 11.3 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 17.7 0.1 0.0 18.3 0.0 0.3 0.2 4.8 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.7 1.0 0.0 0.0 0.6 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.6 0.0 28.6 0.0 0.0 1.1 CSF2RA "alphaGMR, CD116, CSF2R" ENSG00000198223 "Colony stimulating factor 2 receptor subunit alpha" P15509 X 1268800-1310381 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 64.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 248.5;Extravillous trophoblasts: 124.6;Langerhans cells: 365.1;Macrophages: 114.5;monocytes: 575.2;Syncytiotrophoblasts: 312.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 320.2" "Group enriched" "Detected in all" 30 "dendritic cells: 170.7;granulocytes: 320.2;monocytes: 161.1" "Group enriched" "Detected in some" 7 "BEWO: 194.0;HMC-1: 58.3;SK-MEL-30: 142.0" "Low region specificity" "Detected in single" CAB016148 Uncertain "Secreted to blood" NA NA 13000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "CAB016148: AB_626868" "unprognostic (4.19e-2)" "prognostic favorable (2.38e-5)" "unprognostic (5.47e-2)" "unprognostic (4.33e-2)" "unprognostic (4.88e-2)" "prognostic favorable (2.81e-4)" "unprognostic (8.24e-2)" "unprognostic (2.17e-1)" "unprognostic (5.55e-2)" "unprognostic (8.48e-2)" "unprognostic (8.89e-2)" "unprognostic (3.80e-1)" "unprognostic (2.89e-2)" "unprognostic (8.91e-3)" "prognostic unfavorable (5.53e-4)" "unprognostic (3.60e-1)" "unprognostic (9.44e-2)" 10.0 5.5 4.2 25.4 4.4 21.7 6.8 5.2 4.8 5.1 5.4 5.8 5.8 2.5 1.7 5.3 4.1 12.6 2.5 4.0 5.4 2.3 4.6 14.2 20.9 8.5 6.6 1.8 3.3 3.1 1.4 64.4 8.3 2.5 7.4 0.7 3.0 3.0 0.6 4.0 6.6 7.1 7.2 14.9 5.0 1.1 9.0 9.4 1.6 2.0 23.5 12.7 1.5 11.9 0.3 11.5 0.5 0.0 0.0 0.0 194.0 0.3 0.5 0.4 0.1 4.2 1.0 0.2 12.6 0.0 10.3 0.2 0.1 0.0 0.0 3.9 0.1 0.2 8.0 0.1 0.0 4.6 58.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.2 0.4 18.8 1.6 1.8 0.4 0.2 0.5 0.3 0.0 0.5 0.1 0.3 3.7 0.1 142.0 15.1 9.4 16.8 0.0 0.2 5.5 0.1 0.0 0.1 0.1 0.6 0.0 18.5 0.1 17.4 161.1 200.3 0.4 94.9 1.0 2.3 0.3 0.3 170.7 0.6 0.4 0.3 320.2 7.3 48.7 164.0 1.1 65.5 4.2 4.4 5.2 4.8 4.0 5.4 8.5 6.6 8.3 7.2 9.0 11.9 1.2 0.0 7.3 1.3 5.5 7.8 0.9 0.1 0.6 0.6 6.3 2.5 1.2 2.8 3.6 1.8 0.0 248.5 38.3 0.0 0.0 0.3 0.6 7.8 1.2 5.3 0.0 1.3 1.4 1.8 124.6 3.4 0.0 14.7 10.1 0.5 0.7 0.1 75.5 0.0 1.7 0.0 2.0 74.8 365.1 0.3 0.9 114.5 8.8 66.5 575.2 0.3 0.0 1.5 0.9 0.2 0.0 0.4 1.0 0.5 0.0 0.1 2.7 1.5 6.6 1.8 1.4 0.2 0.4 0.0 5.3 312.5 3.3 0.1 0.0 2.5 CSF3 "C17orf33, G-CSF, GCSF, MGC45931" ENSG00000108342 "Colony stimulating factor 3" P09919 17 40015361-40017813 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 123.0;urinary bladder: 57.5" "Cell type enhanced" "Detected in some" "Adipocytes: 57.0;Alveolar cells type 2: 121.2;Basal respiratory cells: 155.9;Club cells: 85.8;Endothelial cells: 192.1;Fibroblasts: 101.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 74.8;U-87 MG: 286.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 6170 "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.59e-3)" "unprognostic (1.57e-2)" "unprognostic (1.73e-1)" "prognostic favorable (8.45e-4)" "unprognostic (1.06e-2)" "unprognostic (3.40e-2)" "unprognostic (1.10e-1)" "unprognostic (1.16e-2)" "unprognostic (1.74e-1)" "unprognostic (2.26e-1)" "unprognostic (2.82e-2)" "unprognostic (7.40e-4)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (4.10e-2)" "unprognostic (4.80e-3)" 41.7 5.9 1.3 14.2 1.2 3.5 7.3 0.9 1.5 25.2 0.7 8.5 0.0 4.1 0.0 6.2 7.2 2.3 16.5 1.1 1.0 3.1 0.5 123.0 0.3 2.0 1.2 1.9 3.8 0.3 10.2 2.5 1.6 16.1 0.5 0.3 3.0 0.1 21.7 1.8 4.3 1.6 2.0 0.9 8.0 1.3 1.3 0.3 3.9 10.5 0.4 57.5 5.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 74.8 0.0 2.8 0.2 0.0 0.0 1.0 0.0 3.2 0.0 0.0 1.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 36.0 11.6 0.0 9.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 286.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.9 1.5 1.1 1.0 2.0 1.2 1.6 2.0 1.3 1.1 57.0 22.4 121.2 0.0 0.0 34.5 5.3 155.9 0.0 0.0 0.1 0.1 0.1 0.0 85.8 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 11.4 0.8 192.1 0.0 0.0 0.0 0.2 0.0 101.5 5.6 23.6 7.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 18.3 0.0 36.5 0.0 0.0 2.2 39.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 14.0 0.0 0.0 34.9 0.0 0.0 37.3 6.4 0.2 0.9 0.9 33.5 0.0 3.2 0.0 0.8 17.3 CSF3R "CD114, GCSFR" ENSG00000119535 "Colony stimulating factor 3 receptor" Q99062 1 36466043-36483278 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 379.7;lung: 136.7;lymphoid tissue: 375.6;placenta: 105.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 230.8;Cytotrophoblasts: 423.8;Kupffer cells: 177.7;monocytes: 197.6;Syncytiotrophoblasts: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 1962.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 1962.3" "Group enriched" "Detected in some" 18 "BEWO: 70.8;NB-4: 20.3;THP-1: 50.3;U-937: 47.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017116, HPA048086" Enhanced "Intracellular and membrane" NA NA 150000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB017116: , HPA048086: AB_2680257" "unprognostic (5.57e-3)" "unprognostic (8.05e-2)" "unprognostic (7.23e-2)" "unprognostic (3.87e-2)" "unprognostic (2.88e-1)" "unprognostic (2.92e-2)" "unprognostic (2.86e-2)" "unprognostic (1.35e-1)" "unprognostic (1.83e-1)" "unprognostic (5.65e-2)" "unprognostic (2.47e-1)" "unprognostic (3.44e-1)" "prognostic unfavorable (5.72e-4)" "unprognostic (6.33e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (2.03e-1)" "unprognostic (2.31e-2)" 36.2 7.1 5.8 148.2 5.6 379.7 13.0 6.7 19.0 5.2 6.3 6.4 2.6 3.1 0.4 5.6 31.5 15.8 14.6 5.5 7.3 9.7 22.9 136.7 7.3 10.3 7.8 3.2 4.9 1.6 5.5 105.1 11.4 7.5 1.8 0.1 7.4 1.8 3.6 1.6 9.8 12.2 9.6 375.6 9.9 1.2 10.7 5.7 5.8 21.7 2.7 22.2 6.2 11.9 0.0 0.0 0.0 0.0 0.0 0.0 70.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 1.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 20.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 1.5 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 47.8 0.0 1.1 280.8 8.7 0.2 56.8 0.6 0.1 0.4 0.2 97.2 0.4 0.1 0.3 1962.3 3.4 24.1 3.3 0.6 158.4 5.8 5.6 6.7 19.0 5.5 7.3 10.3 7.8 11.4 9.6 10.7 11.9 0.7 25.6 230.8 0.0 3.3 1.0 0.5 0.0 0.0 0.0 5.9 4.7 1.8 0.0 10.0 0.0 0.0 423.8 2.9 0.0 0.0 0.0 0.4 0.3 6.4 4.8 0.0 4.6 0.2 0.0 47.3 8.0 1.5 0.2 18.9 1.1 3.9 1.2 64.1 0.0 0.2 0.0 0.0 177.7 39.2 0.7 0.3 111.5 0.0 77.8 197.6 0.2 6.2 0.5 0.3 0.1 0.0 0.0 0.7 0.3 0.0 0.5 6.6 0.2 0.0 0.3 1.0 0.0 0.4 0.2 0.1 1194.8 4.0 0.0 0.0 3.0 CSGALNACT1 "ChGn, CSGalNAcT-1, FLJ11264" ENSG00000147408 "Chondroitin sulfate N-acetylgalactosaminyltransferase 1" Q8TDX6 8 19404161-19758029 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 86.7" "Cell type enhanced" "Detected in many" "Astrocytes: 494.3;Excitatory neurons: 144.4;Granulosa cells: 214.1;Microglial cells: 224.9;Oligodendrocyte precursor cells: 355.9" "Cancer enhanced" "Detected in all" "prostate cancer: 22.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 62.6" "Group enriched" "Detected in all" 5 "B-cells: 44.5;granulocytes: 24.9;T-cells: 62.6" "Cell line enhanced" "Detected in many" "A549: 57.8;BJ hTERT+: 32.3;GAMG: 22.9;RPTEC TERT1: 39.6;U-2197: 36.8;U-87 MG: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068462 Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Golgi apparatus" "HPA068462: " "unprognostic (8.90e-2)" "unprognostic (1.57e-2)" "unprognostic (4.66e-2)" "unprognostic (2.58e-1)" "unprognostic (6.03e-2)" "unprognostic (3.17e-3)" "unprognostic (9.78e-2)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.89e-1)" "unprognostic (2.38e-2)" "unprognostic (1.46e-3)" "unprognostic (1.02e-2)" 19.4 12.5 20.3 8.8 15.7 11.1 7.4 4.8 18.3 18.0 0.7 4.7 3.5 7.0 5.4 31.2 11.8 16.1 35.8 16.3 11.5 6.0 2.8 11.7 7.6 6.3 11.2 57.0 7.9 11.4 3.0 38.8 7.6 31.8 2.5 2.5 6.8 9.8 5.8 4.8 4.7 12.3 6.7 8.7 6.9 2.8 8.9 11.7 86.7 11.0 8.8 23.4 8.1 10.7 2.1 57.8 0.5 0.0 9.3 2.1 7.9 1.4 32.3 0.3 0.3 3.1 1.0 0.0 0.3 0.0 22.9 0.7 0.0 0.0 0.4 7.5 0.4 0.2 16.2 1.9 4.1 0.0 0.1 0.9 1.6 0.7 0.3 0.4 11.6 0.2 0.0 0.1 0.1 2.6 2.9 0.2 0.3 8.3 1.7 0.3 0.1 0.0 39.6 1.6 0.2 0.3 17.2 6.9 2.4 1.5 0.1 0.4 1.0 1.1 1.3 36.8 0.9 0.3 0.0 0.0 26.0 3.4 11.4 0.1 2.9 24.9 5.6 0.1 0.6 44.5 25.7 8.5 2.8 15.9 44.6 11.6 15.6 8.4 0.4 4.2 62.6 11.7 20.3 15.7 4.8 18.3 16.3 11.5 6.3 11.2 7.6 6.7 8.9 10.7 33.3 3.2 1.1 494.3 27.3 4.5 7.4 0.2 0.6 0.3 4.1 0.8 45.8 0.0 0.9 12.9 10.4 1.9 6.2 0.0 1.9 5.7 6.9 7.5 1.2 38.5 3.0 3.2 144.4 1.7 14.6 20.9 2.0 2.0 0.0 214.1 26.7 0.2 15.8 18.5 76.5 0.0 16.2 27.4 6.5 7.4 5.3 14.1 12.4 224.9 3.5 1.0 6.2 355.9 4.6 3.1 0.0 12.0 21.3 21.8 0.0 0.1 1.5 1.0 6.6 2.1 12.0 0.7 0.1 0.5 3.1 8.3 9.6 77.0 0.1 2.8 CSGALNACT2 "GALNACT-2, GALNACT2, MGC40204, PRO0082" ENSG00000169826 "Chondroitin sulfate N-acetylgalactosaminyltransferase 2" Q8N6G5 10 43138445-43185302 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 133.9" "Cell type enhanced" "Detected in many" "Langerhans cells: 121.6;Macrophages: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031540 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA031540: AB_10599943" "unprognostic (1.65e-1)" "unprognostic (2.70e-2)" "unprognostic (9.10e-2)" "unprognostic (6.41e-2)" "unprognostic (1.95e-1)" "unprognostic (8.28e-3)" "unprognostic (2.85e-3)" "unprognostic (4.95e-2)" "unprognostic (2.96e-1)" "unprognostic (3.43e-3)" "unprognostic (7.65e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (3.53e-7)" "unprognostic (2.68e-2)" "unprognostic (1.40e-1)" "unprognostic (2.47e-1)" "unprognostic (4.05e-3)" 19.7 10.6 8.8 24.1 10.8 133.9 12.9 15.1 13.3 15.1 12.6 15.1 9.2 19.5 8.4 10.5 15.5 25.4 12.8 8.5 10.8 8.8 13.9 26.8 22.5 10.7 9.7 17.0 7.8 8.0 11.6 26.4 11.1 13.4 11.6 9.8 7.9 10.9 14.6 11.0 11.5 20.8 9.4 26.5 10.1 9.2 9.9 27.9 9.9 17.2 17.4 24.0 12.1 13.5 12.6 8.2 15.1 14.4 23.0 38.5 3.7 44.7 59.8 19.3 30.0 2.9 12.7 20.8 10.8 40.6 9.2 11.4 12.6 16.8 31.3 24.9 9.3 10.8 7.9 8.6 50.0 25.3 21.8 38.6 18.1 43.1 89.3 24.3 25.0 30.7 4.6 60.1 39.9 6.5 19.3 15.1 6.5 4.2 10.7 11.9 15.0 8.8 17.1 6.6 13.6 26.8 11.6 11.9 28.8 13.0 15.7 20.5 37.3 16.5 26.2 52.3 30.4 15.4 23.2 10.9 35.1 60.8 7.9 14.7 11.9 19.4 7.3 14.2 6.4 3.0 5.5 5.7 14.4 3.0 6.4 5.4 11.2 11.3 21.8 4.1 7.1 6.9 8.8 10.8 15.1 13.3 8.5 10.8 10.7 9.7 11.1 9.4 9.9 13.5 16.3 16.0 18.7 23.8 20.5 17.7 13.3 7.0 6.2 13.1 10.7 8.5 10.9 5.7 9.6 11.0 10.4 2.1 47.8 1.7 0.0 5.9 2.1 12.0 22.0 16.8 9.0 18.5 42.5 6.9 6.1 31.4 4.6 11.3 48.1 23.5 11.4 11.9 16.4 8.4 41.1 1.6 4.1 68.6 121.6 1.4 17.1 82.6 8.8 16.9 41.5 4.1 35.0 45.2 54.5 13.7 3.1 12.4 33.8 12.7 1.5 4.4 5.8 8.5 26.3 27.7 25.3 17.8 18.3 3.6 12.1 1.5 37.4 7.2 1.6 7.0 CSH1 "CSA, CSMT, FLJ75407, hCS-A, PL" ENSG00000136488 "Chorionic somatomammotropin hormone 1" P0DML2 17 63894909-63896661 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 247 "placenta: 9786.7" "Group enriched" "Detected in some" 24 "Extravillous trophoblasts: 542.0;Syncytiotrophoblasts: 1092.3" "Cancer enriched" "Detected in single" 8 "testis cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "BEWO: 11.8;SuSa: 17.0" "CAB026374, HPA043715" Enhanced "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB026374: , HPA043715: AB_2678632" "unprognostic (6.99e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 6.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.7 3.9 0.0 0.2 9786.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 39.6 0.0 26.1 19.9 0.1 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.5 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 542.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1092.3 0.0 0.0 0.0 0.0 CSH2 "CS-2, CSB, hCS-B" ENSG00000213218 "Chorionic somatomammotropin hormone 2" P0DML3 17 63872012-63873766 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 218 "placenta: 3289.0" "Cell type enriched" "Detected in some" 12 "Syncytiotrophoblasts: 275.5" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "BEWO: 9.3;SuSa: 13.1" HPA043715 Supported "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA043715: AB_2678632" "unprognostic (1.68e-1)" "unprognostic (1.85e-1)" "unprognostic (1.86e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 1.1 0.0 1.9 3289.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 15.0 0.0 8.6 5.2 0.2 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 275.5 0.0 0.0 0.0 0.0 CSHL1 "CS-5, CSHP1, CSL, hCS-L, MGC149868" ENSG00000204414 "Chorionic somatomammotropin hormone like 1" Q14406 17 63909597-63918838 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "placenta: 150.0" "Cell type enriched" "Detected in some" 12 "Syncytiotrophoblasts: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025646, HPA043715" Enhanced "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB025646: , HPA043715: AB_2678632" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 1.4 150.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 21.6 0.0 0.0 0.0 0.0 CSN1S1 "CASA, CSN1" ENSG00000126545 "Casein alpha s1" P47710 4 69931068-69946574 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Milk protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "breast: 1391.5" "Cell type enriched" "Detected in some" 47 "Breast glandular cells: 8261.0" "Cancer enriched" "Detected in some" 10 "breast cancer: 17.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035659, HPA057031" Enhanced "Secreted in female reproductive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "HPA035659: AB_10696356, HPA057031: AB_2683315" "unprognostic (1.52e-2)" "unprognostic (1.01e-1)" 16.0 0.0 0.1 0.5 0.0 0.0 1391.5 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.4 1.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.6 0.2 0.0 0.1 0.0 0.4 0.1 28.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 8261.0 172.2 2.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.1 0.3 0.0 2.1 0.0 0.0 0.3 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.6 0.0 0.0 0.0 5.5 0.0 0.0 0.0 CSN2 CASB ENSG00000135222 "Casein beta" P05814 4 69955256-69961007 "Predicted secreted proteins" "Milk protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 94 "breast: 307.2" "Cell type enriched" "Detected in some" 97 "Breast glandular cells: 33136.9" "Cancer enriched" "Detected in single" 156 "breast cancer: 75.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041036 Supported "Secreted in female reproductive system" NA NA "Cluster 5: Breast - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "HPA041036: AB_10793865" 0.0 0.0 0.0 0.0 0.0 0.0 307.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 113.1 0.0 0.0 0.0 29.8 0.0 0.0 0.0 0.0 0.0 33136.9 340.4 0.0 0.0 0.0 0.0 0.0 0.0 72.4 0.0 0.0 0.0 0.8 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 CSN3 CSN10 ENSG00000171209 "Casein kappa" P07498 4 70242588-70251428 "Predicted secreted proteins" "Milk protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "breast: 378.1" "Cell type enriched" "Detected in some" 48 "Breast glandular cells: 2554.0" "Cancer enriched" "Detected in some" 5 "breast cancer: 35.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035953, HPA035954" Enhanced "Secreted in female reproductive system" NA NA "Cluster 5: Breast - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "HPA035953: AB_10673226, HPA035954: AB_2674884" 0.0 0.0 0.0 0.0 0.0 0.0 378.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 10.3 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 2554.0 52.2 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.1 3.7 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.9 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 CST1 ENSG00000170373 "Cystatin SN" P01037 20 23747562-23751268 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 119 "salivary gland: 28401.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 14.3;Collecting duct cells: 79.1;Glandular and luminal cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 1142.2" "CAB026769, HPA043706, HPA044763" Enhanced "Secreted to digestive system" NA NA 6300000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "CAB026769: , HPA043706: AB_2678627, HPA044763: AB_2679080" "prognostic favorable (4.00e-4)" "unprognostic (2.47e-1)" "unprognostic (3.11e-1)" "unprognostic (3.62e-2)" "unprognostic (1.99e-1)" "unprognostic (5.27e-2)" "unprognostic (1.99e-1)" "unprognostic (1.56e-1)" "unprognostic (1.83e-1)" "unprognostic (1.44e-1)" "unprognostic (2.34e-2)" "unprognostic (1.39e-1)" "unprognostic (8.26e-2)" "unprognostic (9.58e-2)" "unprognostic (2.58e-1)" "unprognostic (9.00e-2)" "unprognostic (9.91e-3)" 0.1 0.3 0.1 1.1 0.1 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.0 3.7 0.4 0.1 0.2 238.8 8.0 0.1 0.1 0.0 0.0 0.1 0.0 0.8 0.7 7.1 37.3 0.0 0.1 4.1 1.4 13.0 0.2 0.0 28401.8 0.6 0.0 3.2 0.0 0.0 0.4 0.0 0.8 0.2 0.1 2.1 0.0 0.0 0.7 0.7 0.0 0.4 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 172.6 0.3 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.4 0.0 0.1 0.0 0.1 0.0 51.2 0.0 4.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 45.3 0.1 0.0 0.0 0.0 4.4 1142.2 0.7 0.0 0.1 0.0 0.3 5.6 0.0 0.0 223.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.8 0.7 1.4 0.4 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 14.3 0.0 79.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 5.7 2.2 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 31.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.5 0.0 0.1 0.0 0.4 0.0 0.0 0.5 CST11 "CST8L, CTES2, dJ322G13.6" ENSG00000125831 "Cystatin 11" Q9H112 20 23450403-23452876 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 473 "epididymis: 210.7" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Endometrial stromal cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053399 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 36: Stromal cells - Cell proliferation" "HPA053399: AB_2682136" "unprognostic (9.42e-2)" "unprognostic (2.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 210.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.3 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CST2 ENSG00000170369 "Cystatin SA" P09228 20 23823769-23826729 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 637 "salivary gland: 5987.1" "Group enriched" "Detected in some" 4 "Granulosa cells: 5.2;Melanocytes: 16.0" "Cancer enhanced" "Detected in many" "prostate cancer: 24.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "RT4: 67.7" "CAB024963, HPA043706, HPA044763" Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "CAB024963: , HPA043706: AB_2678627, HPA044763: AB_2679080" "unprognostic (1.57e-2)" "unprognostic (3.23e-2)" "unprognostic (1.04e-1)" "unprognostic (3.10e-1)" "unprognostic (1.64e-2)" "unprognostic (5.17e-3)" "unprognostic (1.28e-2)" "unprognostic (2.75e-3)" "unprognostic (2.73e-1)" "unprognostic (4.82e-3)" "unprognostic (6.43e-3)" "unprognostic (2.51e-1)" "unprognostic (4.58e-11)" "unprognostic (1.29e-3)" "unprognostic (3.22e-1)" "unprognostic (4.30e-1)" "unprognostic (1.71e-1)" 1.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.1 0.1 0.2 0.1 0.0 0.2 4.8 2.4 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 1.6 9.3 0.1 2.0 1.0 0.0 2.5 0.0 0.0 5987.1 1.3 0.0 0.4 0.2 3.8 0.0 0.1 0.6 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.0 0.0 1.8 67.7 0.0 0.0 0.0 0.0 5.4 0.9 0.0 0.0 4.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.4 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 16.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4217.6" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 18746.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4967.5;intermediate monocyte: 6424.5;myeloid DC: 7959.0;non-classical monocyte: 4297.7;plasmacytoid DC: 4427.4" "Group enriched" "Detected in all" 9 "dendritic cells: 7959.0;monocytes: 6424.5" "Cell line enhanced" "Detected in many" "ASC diff: 1733.4;ASC TERT1: 1179.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1040000000 2800000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" 1046.2 707.6 3041.2 262.3 3117.9 170.8 900.3 2823.3 4217.6 587.8 3094.8 788.7 389.6 708.3 875.9 557.1 802.7 583.0 1275.3 2976.3 2707.6 517.4 833.6 595.8 463.5 3258.4 3096.2 575.8 944.1 320.0 670.1 165.9 2939.3 773.9 416.9 46.9 2008.0 441.5 749.0 497.1 800.3 367.6 3028.1 723.7 979.9 761.3 3302.7 418.9 658.8 517.4 208.1 703.0 618.4 2883.1 155.2 328.2 75.4 175.8 1733.4 1179.8 145.3 261.4 350.7 170.3 137.7 625.1 219.7 0.8 241.0 345.2 221.3 496.2 69.6 499.9 51.9 0.9 253.5 157.6 61.1 1082.9 621.2 7.5 251.0 919.0 415.9 226.6 241.5 352.5 268.5 18.5 147.6 4.0 239.5 234.4 1.5 162.2 103.5 461.9 752.2 5.7 96.4 215.2 708.0 328.3 84.7 98.2 191.1 54.6 343.3 107.7 156.5 548.2 702.0 163.4 119.0 231.6 97.7 157.1 6.2 1.8 138.0 339.5 184.0 48.1 4967.5 33.2 66.9 6424.5 25.5 23.1 18.3 45.8 7959.0 13.6 16.9 31.1 809.3 191.4 4297.7 4427.4 13.6 4250.8 3041.2 3117.9 2823.3 4217.6 2976.3 2707.6 3258.4 3096.2 2939.3 3028.1 3302.7 2883.1 662.4 115.4 168.8 849.5 93.8 942.9 571.1 568.2 213.9 152.4 660.2 512.1 240.7 1361.2 514.5 641.9 29.2 476.8 603.3 1889.9 414.8 489.9 46.2 441.1 795.0 728.2 882.1 252.1 4.5 783.6 308.7 3026.2 981.7 631.0 359.9 687.0 491.9 2563.0 1816.7 48.8 11.2 1360.6 691.7 4301.1 18746.6 184.3 2132.6 4542.6 1563.5 87.1 2025.6 248.7 99.9 263.9 6.0 1458.5 2342.1 1790.4 67.9 786.0 4301.1 1098.6 364.4 36.3 2195.7 1417.0 846.2 125.5 400.6 461.5 822.0 469.0 117.4 208.1 1039.4 1079.7 CST4 ENSG00000101441 "Cystatin S" P01036 20 23685640-23689038 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 514 "salivary gland: 29036.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.7;Collecting duct cells: 9.2;Glandular and luminal cells: 3.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CACO-2: 5.5;RT4: 13.6" "HPA043706, HPA044763" Supported "Secreted to digestive system" NA NA 2800000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "HPA043706: AB_2678627, HPA044763: AB_2679080" "unprognostic (2.80e-1)" "unprognostic (7.88e-2)" "unprognostic (2.48e-1)" "unprognostic (1.09e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (4.98e-5)" "unprognostic (1.00e-2)" "unprognostic (9.52e-2)" "unprognostic (2.11e-2)" "unprognostic (2.31e-1)" "unprognostic (7.95e-2)" "prognostic favorable (2.88e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 56.4 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 29.9 0.0 0.0 3.8 0.0 2.4 0.0 0.0 29036.2 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 13.6 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 CST5 ENSG00000170367 "Cystatin D" P28325 20 23875934-23879748 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 959 "salivary gland: 2156.1" "Group enriched" "Detected in some" 8 "Alveolar cells type 1: 9.6;Langerhans cells: 3.4" "Cancer enriched" "Detected in many" 5 "breast cancer: 17.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB024944, HPA061449" Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 11: Alveolar cells - Smell perception" "CAB024944: , HPA061449: AB_2684523" "unprognostic (2.43e-1)" "unprognostic (8.83e-2)" "unprognostic (3.20e-1)" "unprognostic (3.19e-1)" "unprognostic (1.51e-2)" "unprognostic (4.73e-1)" "unprognostic (4.31e-2)" "unprognostic (1.76e-2)" "unprognostic (2.32e-1)" "unprognostic (1.35e-1)" "unprognostic (4.83e-3)" "unprognostic (5.14e-2)" "unprognostic (2.31e-1)" 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.3 0.4 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2156.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 CST6 ENSG00000175315 "Cystatin E/M" Q15828 11 66012008-66013505 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "skin 1: 761.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.0;Club cells: 115.2;Pancreatic endocrine cells: 368.1;Respiratory ciliated cells: 404.0" "Group enriched" "Detected in many" 5 "thyroid cancer: 171.0;urothelial cancer: 43.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 130.2;CAPAN-2: 364.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB019316, HPA044963" Enhanced Approved "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 82000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Cytosol "CAB019316: , HPA044963: AB_2679158" "unprognostic (3.01e-2)" "unprognostic (5.10e-2)" "unprognostic (1.14e-1)" "unprognostic (3.59e-2)" "unprognostic (5.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (5.02e-1)" "unprognostic (8.89e-3)" "unprognostic (1.29e-3)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (5.89e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-2)" "unprognostic (2.59e-2)" 3.2 0.3 0.1 0.3 0.1 0.2 28.5 0.8 0.4 7.4 0.8 0.4 0.0 0.3 0.6 34.6 14.9 0.5 2.8 0.1 0.3 2.6 0.3 18.3 0.0 0.2 0.2 0.7 0.7 2.1 1.6 8.1 0.1 0.9 0.0 0.0 7.4 4.9 2.0 761.4 0.3 0.1 0.1 0.2 0.6 1.8 0.4 2.7 21.4 0.0 2.2 1.2 22.5 0.2 130.2 0.0 0.0 0.6 0.0 0.0 37.6 1.4 0.0 0.3 0.2 1.0 364.6 0.0 1.8 5.1 0.1 4.5 0.0 32.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.8 0.6 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.5 0.5 0.8 0.2 0.7 0.0 0.0 35.8 0.4 0.1 0.8 0.1 0.0 0.2 2.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.8 0.4 0.1 0.3 0.2 0.2 0.1 0.1 0.4 0.2 0.1 93.0 6.1 0.0 0.6 1.1 1.7 41.4 0.6 0.0 5.3 7.1 1.2 0.0 115.2 58.8 0.0 33.3 0.0 0.1 0.0 57.4 0.2 7.7 0.1 0.9 0.0 0.0 0.0 21.6 24.4 2.0 0.0 0.6 21.6 0.1 0.4 0.1 41.1 0.0 0.0 0.0 24.4 1.4 10.0 0.8 0.0 5.3 5.4 0.0 1.1 1.3 0.0 0.0 0.0 368.1 1.1 0.4 9.8 1.9 0.0 0.5 404.0 0.1 0.0 0.3 16.0 5.2 17.6 1.0 27.6 64.2 0.7 0.0 0.4 6.1 CST7 ENSG00000077984 "Cystatin F" O76096 20 24949269-24959928 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 1095.6" "Group enriched" "Detected in many" 9 "dendritic cells: 1094.4;Langerhans cells: 541.7;monocytes: 659.7;NK-cells: 1385.2;T-cells: 544.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 1287.0" "Group enriched" "Detected in all" 27 "granulocytes: 342.2;NK-cells: 655.3;T-cells: 1287.0" "Cell line enhanced" "Detected in some" "HL-60: 77.8;HMC-1: 204.6;NB-4: 212.1;U-937: 380.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Low region specificity" "Detected in all" HPA040442 Enhanced "Secreted to blood" NA NA 26000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA040442: AB_2676988" "prognostic favorable (6.55e-4)" "prognostic favorable (7.90e-4)" "unprognostic (9.37e-2)" "prognostic favorable (9.17e-6)" "unprognostic (2.38e-2)" "prognostic favorable (5.85e-5)" "unprognostic (1.00e-2)" "unprognostic (8.66e-2)" "unprognostic (2.84e-3)" "unprognostic (7.93e-2)" "unprognostic (5.05e-2)" "unprognostic (7.42e-2)" "prognostic unfavorable (4.37e-6)" "unprognostic (7.64e-2)" "unprognostic (3.38e-1)" "unprognostic (4.45e-1)" "unprognostic (7.62e-2)" 18.0 3.6 1.3 24.2 1.6 1095.6 5.7 2.8 5.1 4.5 1.7 5.7 5.9 4.6 4.8 5.4 10.4 17.7 5.6 1.5 1.4 5.4 12.7 49.3 73.4 2.4 1.4 2.5 3.9 1.0 2.2 4.4 2.0 4.3 5.1 0.2 6.6 2.0 1.9 4.5 13.9 5.0 1.6 148.1 8.7 1.7 1.6 17.3 5.6 4.4 16.4 19.2 5.2 1.4 0.3 0.6 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.3 1.7 0.0 0.4 0.0 77.8 204.6 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 2.8 0.0 0.2 2.0 212.1 0.1 0.0 0.2 0.5 7.7 0.1 0.0 0.1 0.3 0.2 0.0 0.1 1.0 0.1 0.0 13.3 0.2 0.1 0.8 0.2 0.5 0.1 0.1 0.2 0.1 380.4 0.1 74.3 3.0 10.4 1287.0 3.4 720.2 3.7 186.8 904.7 28.4 3.9 38.8 531.2 342.2 655.3 3.5 7.2 123.0 600.8 1.3 1.6 2.8 5.1 1.5 1.4 2.4 1.4 2.0 1.6 1.6 1.4 8.1 9.6 14.1 0.0 14.5 22.8 0.3 0.0 0.0 0.0 2.5 2.4 1.4 4.3 0.6 0.0 0.0 0.2 1094.4 0.3 0.0 1.3 0.0 1.3 0.7 3.2 0.0 46.7 0.0 3.7 0.1 5.2 11.2 1.2 60.0 0.0 11.0 3.8 1.4 0.0 0.0 0.1 0.0 16.2 541.7 0.0 0.0 61.9 24.9 1.9 659.7 0.0 1385.2 0.0 0.1 0.2 0.1 0.0 90.9 0.1 0.4 2.3 2.2 0.0 0.0 2.2 3.6 0.0 0.2 0.5 23.9 1.1 544.5 0.0 0.6 0.6 CST8 "CRES, CTES5" ENSG00000125815 "Cystatin 8" O60676 20 23491101-23496010 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 203 "testis: 22.3" "Group enriched" "Detected in some" 128 "Early spermatids: 188.7;Late spermatids: 119.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 188.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 119.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CST9 "CLM, CTES7A" ENSG00000173335 "Cystatin 9" Q5W186 20 23602410-23605917 "Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Thiol protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "breast: 1.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 37 "breast cancer: 9.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA029190 Uncertain "Secreted in female reproductive system" NA NA "Cluster 5: Breast - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA029190: AB_10602804" "unprognostic (2.06e-2)" "unprognostic (2.21e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CST9L "bA218C14.1, CTES7B" ENSG00000101435 "Cystatin 9 like" Q9H4G1 20 23564732-23568484 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 337 "epididymis: 26.4;testis: 87.9" "Cell type enhanced" "Detected in some" "Early spermatids: 4.0;Late spermatids: 13.2;Leydig cells: 2.5;Peritubular cells: 1.5;Spermatocytes: 1.6" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 20 "HEL: 2.1" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (2.10e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CSTL1 "CTES1, dJ322G13.4" ENSG00000125823 "Cystatin like 1" Q9H114 20 23439685-23444930 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "testis: 4.4" "Group enriched" "Detected in some" 631 "Early spermatids: 51.3;Late spermatids: 74.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.14e-1)" "unprognostic (1.54e-1)" "unprognostic (3.25e-3)" "unprognostic (2.04e-1)" "unprognostic (6.58e-2)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (5.40e-2)" "unprognostic (3.63e-1)" "unprognostic (2.97e-1)" "unprognostic (6.87e-2)" "unprognostic (2.35e-1)" "unprognostic (5.36e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CTBS CTB ENSG00000117151 Chitobiase Q01459 1 84549611-84574480 "Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 7 "basal ganglia: 7.4" "CAB017043, HPA023594, HPA048810" Approved Uncertain Cytosol "Intracellular and membrane" NA NA 370000000 "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB017043: , HPA023594: AB_1847311, HPA048810: " "unprognostic (7.76e-2)" "unprognostic (1.28e-2)" "unprognostic (1.11e-1)" "unprognostic (1.36e-1)" "unprognostic (9.36e-2)" "unprognostic (3.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.76e-1)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (9.23e-2)" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.08e-2)" "unprognostic (4.89e-2)" "unprognostic (3.12e-1)" "unprognostic (4.04e-2)" 1.5 1.4 0.4 1.4 0.8 3.3 1.6 1.0 0.6 1.2 2.1 1.2 0.9 1.5 3.1 1.0 1.1 1.2 1.0 0.2 0.6 1.7 3.7 1.4 1.6 1.3 0.9 0.8 1.7 1.6 0.5 1.2 1.5 2.2 1.4 1.4 3.3 0.8 0.8 2.4 1.2 1.1 0.5 2.5 1.4 0.5 0.8 1.0 1.3 0.9 1.0 1.0 0.5 1.3 0.9 0.3 0.2 0.2 2.7 3.2 0.6 0.6 2.2 0.3 0.8 0.1 1.1 1.2 0.2 1.4 0.3 0.4 0.0 0.9 0.9 1.1 0.3 0.8 0.1 0.1 1.6 0.8 0.4 2.4 1.6 0.8 1.2 1.9 0.9 0.5 0.7 2.2 0.6 0.0 0.5 0.9 0.2 0.2 0.3 0.2 0.3 0.8 1.9 0.4 0.1 0.4 0.2 0.9 1.1 0.5 0.5 0.9 1.5 1.1 0.1 1.5 0.7 0.6 0.2 0.3 0.8 1.1 0.8 0.5 0.1 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.3 0.1 0.0 0.0 0.4 0.8 1.0 0.6 0.2 0.6 1.3 0.9 1.5 0.5 0.8 1.3 43.6 9.6 23.4 10.4 37.4 30.3 30.2 28.0 34.1 5.9 33.1 15.6 5.8 31.5 25.5 23.9 41.7 26.8 25.4 30.2 43.0 20.2 3.3 24.1 24.4 29.9 23.0 14.1 6.2 19.2 24.2 28.1 25.0 19.4 43.8 9.7 49.6 70.8 48.2 3.3 4.3 18.9 16.2 75.5 27.9 3.7 21.1 58.8 7.2 20.6 56.5 21.8 18.6 5.5 9.0 19.1 25.2 24.5 59.8 36.7 30.0 44.4 38.2 41.9 13.1 20.2 16.6 10.4 12.8 27.3 24.7 25.6 26.8 25.3 18.4 29.9 CTDP1 FCP1 ENSG00000060069 "CTD phosphatase subunit 1" Q9Y5B0 18 79679803-79754510 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cataract, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 113.1;Late spermatids: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032641, HPA040394, HPA070389" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Vesicles "CAB032641: AB_2261235, HPA040394: AB_10794029, HPA070389: AB_2732155" "unprognostic (1.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" "prognostic favorable (6.43e-4)" "unprognostic (2.64e-2)" "unprognostic (7.99e-2)" "unprognostic (3.47e-3)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "prognostic favorable (5.51e-5)" "unprognostic (5.16e-2)" "unprognostic (8.58e-2)" "unprognostic (2.85e-2)" "unprognostic (4.74e-2)" 9.3 7.4 3.8 7.2 3.9 13.7 8.9 3.3 4.2 7.8 4.1 11.1 7.2 10.4 1.4 10.7 8.1 4.0 7.2 3.3 3.3 7.9 9.5 9.3 8.7 5.3 4.2 5.0 9.0 3.3 6.9 4.2 4.0 8.2 3.1 1.5 9.5 3.9 11.9 20.5 10.9 3.1 3.3 13.5 9.9 22.2 4.0 6.5 8.0 3.1 3.7 9.6 8.6 4.4 13.4 14.0 7.7 11.0 6.0 5.0 25.9 9.6 6.1 7.6 7.5 9.4 8.0 17.2 4.2 5.6 9.1 16.4 6.6 8.8 3.1 16.9 12.4 8.5 6.6 12.9 8.7 37.6 20.5 8.4 8.3 8.1 3.8 4.6 9.2 12.2 11.2 8.1 3.0 11.5 25.4 29.5 12.7 4.2 19.1 20.7 10.1 20.0 5.6 13.1 12.0 12.4 10.2 9.8 13.9 5.8 8.0 21.7 12.9 12.9 19.4 5.3 9.7 7.4 27.6 16.1 11.0 18.8 9.3 0.0 0.4 3.2 0.5 0.4 0.4 0.2 0.4 0.8 0.6 0.1 0.5 0.3 1.0 1.1 0.4 0.1 0.1 0.2 3.8 3.9 3.3 4.2 3.3 3.3 5.3 4.2 4.0 3.3 4.0 4.4 7.4 0.0 4.1 3.6 9.2 8.5 5.0 4.0 11.4 9.5 7.7 6.5 3.8 4.3 4.5 3.7 14.6 8.8 24.2 20.0 1.9 5.4 113.1 18.6 8.0 7.5 6.0 13.5 7.7 7.2 8.0 4.8 19.9 24.0 7.0 7.8 6.4 5.7 8.8 23.5 6.6 16.6 6.1 7.5 9.5 123.2 7.8 13.8 7.2 6.5 6.5 6.5 19.6 3.0 8.9 10.2 14.9 10.5 15.2 11.8 10.0 6.8 9.6 14.8 0.0 5.9 7.4 18.0 10.5 10.5 10.1 19.0 18.3 8.0 11.7 12.6 CTHRC1 ENSG00000164932 "Collagen triple helix repeat containing 1" Q96CG8 8 103371538-103382989 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 69.1;gallbladder: 87.8;placenta: 90.1;urinary bladder: 84.6" "Cell type enhanced" "Detected in many" "Endothelial cells: 95.2;Fibroblasts: 181.6;Langerhans cells: 45.9;Melanocytes: 49.8;Smooth muscle cells: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 294.6;fHDF/TERT166: 138.1;HHSteC: 197.1;HSkMC: 406.6;WM-115: 386.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059806, HPA061896" Approved Approved Nucleoplasm "Secreted in other tissues" NA NA 420000 "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA059806: AB_2684130, HPA061896: AB_2684633" "unprognostic (2.04e-2)" "unprognostic (4.58e-1)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (4.17e-2)" "unprognostic (3.64e-2)" "unprognostic (8.63e-2)" "unprognostic (1.12e-2)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.22e-14)" "unprognostic (2.33e-3)" "unprognostic (3.21e-2)" "unprognostic (7.96e-3)" "unprognostic (2.37e-3)" 69.1 2.8 1.6 15.4 1.8 0.5 39.0 5.7 6.3 12.8 0.4 6.6 6.3 18.7 3.3 9.7 5.3 87.8 8.9 1.5 2.3 2.3 0.8 8.9 13.8 2.0 1.6 4.2 3.7 2.2 3.7 90.1 2.5 4.7 6.2 2.4 17.0 5.6 3.6 32.5 3.5 19.7 1.8 2.6 3.6 3.6 1.5 6.2 9.1 4.1 16.0 84.6 6.6 3.3 12.1 0.9 3.3 0.8 90.6 294.6 0.2 34.8 9.3 3.7 5.0 1.1 8.3 1.5 36.6 138.1 0.2 0.4 0.1 0.2 17.7 0.5 0.0 0.5 0.6 19.2 197.1 0.9 0.7 406.6 0.5 30.7 0.4 1.4 60.2 2.3 0.5 91.6 18.7 1.7 17.2 41.1 11.0 0.4 58.0 35.8 30.9 1.1 2.9 0.2 5.7 4.3 0.1 0.2 110.8 12.6 0.1 0.2 49.0 4.6 1.8 4.8 0.4 3.0 0.8 0.6 2.2 0.2 386.9 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.2 0.0 0.1 1.6 1.8 5.7 6.3 1.5 2.3 2.0 1.6 2.5 1.8 1.5 3.3 36.9 3.2 2.3 1.0 6.7 32.0 0.2 12.1 0.0 0.3 0.9 1.4 0.8 1.5 3.6 3.7 0.0 5.6 0.9 0.0 0.0 4.1 0.5 6.4 9.8 95.2 1.2 0.8 2.3 0.6 11.3 181.6 0.0 11.5 0.0 0.5 17.5 0.1 8.0 0.0 2.0 0.0 4.1 0.3 45.9 0.8 12.5 0.9 49.8 3.7 0.6 5.5 1.0 4.5 1.8 1.8 0.0 0.4 24.2 0.8 0.0 0.5 0.8 1.2 0.0 4.7 77.4 4.3 16.5 0.3 27.3 16.6 3.5 1.2 0.2 0.5 CTLA4 "CD, CD152, CELIAC3, CTLA-4, GSE, IDDM12" ENSG00000163599 "Cytotoxic T-lymphocyte associated protein 4" P16410 2 203867771-203873965 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Diabetes mellitus, Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 37.4" "Cell type enriched" "Detected in some" 8 "T-cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 7 "T-reg: 44.5" "Lineage enriched" "Detected in single" 445 "T-cells: 44.5" "Cell line enhanced" "Detected in some" "Karpas-707: 1.5;SK-MEL-30: 3.0;U-266/70: 4.3;U-266/84: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.92e-2)" "unprognostic (9.13e-3)" "unprognostic (1.47e-3)" "unprognostic (9.89e-6)" "unprognostic (1.86e-1)" "prognostic favorable (4.48e-5)" "unprognostic (1.02e-1)" "unprognostic (1.75e-2)" "unprognostic (1.84e-3)" "unprognostic (2.65e-3)" "unprognostic (2.77e-1)" "unprognostic (3.76e-1)" "unprognostic (9.86e-10)" "unprognostic (4.13e-2)" "unprognostic (7.45e-2)" "unprognostic (4.94e-2)" "unprognostic (1.19e-2)" 1.1 0.2 0.4 18.5 0.4 6.1 1.0 0.4 0.7 0.6 0.5 1.3 0.3 0.3 0.0 1.6 0.6 5.2 0.5 0.5 0.5 0.6 0.7 2.9 37.4 1.3 0.7 0.1 0.4 0.5 0.3 0.3 1.1 1.5 3.2 0.0 0.5 1.0 0.1 0.7 6.2 0.8 0.6 3.9 2.9 1.1 0.5 10.1 1.1 0.2 17.0 5.8 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 4.3 13.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 6.2 0.8 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 44.5 0.6 0.4 0.4 0.4 0.7 0.5 0.5 1.3 0.7 1.1 0.6 0.5 0.5 0.4 0.0 3.2 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 4.1 0.0 1.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 3.3 0.0 2.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 1.0 0.2 0.9 0.1 41.9 0.0 0.0 0.1 CTNS "CTNS-LSB, PQLC4, SLC66A4" ENSG00000040531 "Cystinosin, lysosomal cystine transporter" O60931 17 3636459-3663103 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis, Protein transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 35.5;Late spermatids: 29.3;Theca cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 34.3;granulocytes: 27.9;monocytes: 10.4" "Cell line enhanced" "Detected in all" "HDLM-2: 144.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046947 Supported "Vesicles,Intermediate filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Intermediate filaments" "HPA046947: AB_2679872" "unprognostic (1.64e-1)" "unprognostic (1.70e-1)" "unprognostic (1.21e-1)" "unprognostic (8.25e-2)" "unprognostic (8.39e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.28e-2)" "unprognostic (8.02e-2)" "unprognostic (1.94e-1)" "unprognostic (6.62e-3)" "prognostic favorable (6.39e-5)" "unprognostic (8.40e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-1)" "unprognostic (5.64e-2)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" 10.3 19.5 9.5 10.0 17.0 10.2 9.6 13.5 12.1 20.3 12.1 8.3 12.2 11.3 6.4 8.7 10.3 13.1 10.5 10.8 10.3 15.2 15.9 11.6 10.0 16.5 16.8 12.1 27.0 13.6 9.6 12.9 18.0 10.8 7.2 6.8 12.0 11.6 15.3 19.2 11.0 8.6 10.9 12.1 15.0 24.8 13.2 8.8 9.2 7.4 9.5 9.1 9.4 28.0 17.6 37.0 22.6 18.2 34.5 16.9 13.0 19.6 28.8 21.1 26.0 21.0 16.0 10.2 17.8 11.6 55.9 40.1 19.8 12.1 12.6 144.3 33.7 10.8 32.2 19.3 46.5 8.0 81.3 23.8 14.2 20.2 15.4 28.1 22.2 18.7 12.6 15.9 16.6 15.1 7.8 7.9 9.8 12.2 16.8 16.4 9.3 23.0 15.3 16.2 3.9 17.2 19.2 24.4 20.3 19.0 17.1 7.7 24.2 17.2 11.6 40.3 13.3 12.4 20.0 4.2 28.1 7.8 11.8 27.9 10.4 21.8 3.0 6.9 4.9 5.8 4.0 5.7 9.7 4.9 4.5 5.5 3.1 5.2 7.1 34.3 4.3 7.3 9.5 17.0 13.5 12.1 10.8 10.3 16.5 16.8 18.0 10.9 13.2 28.0 4.4 3.2 2.2 6.5 4.8 1.7 3.5 2.5 4.0 1.6 6.3 5.0 5.2 5.7 2.7 12.9 10.4 6.1 5.2 3.6 0.0 6.7 35.5 5.7 4.4 5.3 2.4 4.0 3.4 6.4 7.1 6.0 7.7 4.3 8.2 6.7 9.3 7.6 25.2 5.0 3.4 2.5 4.1 7.2 5.9 29.3 9.6 12.1 5.4 3.7 10.0 6.5 3.1 5.5 11.1 6.4 3.3 12.8 4.5 6.5 3.2 9.5 7.0 3.9 6.6 3.7 3.5 19.7 8.7 2.9 2.4 8.5 3.3 30.9 1.8 3.2 CTRB1 CTRB ENSG00000168925 "Chymotrypsinogen B1" P17538 16 75218988-75226338 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2384 "pancreas: 133851.7" "Cell type enriched" "Detected in some" 21 "Exocrine glandular cells: 31269.6" "Cancer enriched" "Detected in some" 1905 "pancreatic cancer: 962.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.2;HDLM-2: 1.6" "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (1.76e-1)" "unprognostic (2.62e-1)" "unprognostic (3.55e-1)" "unprognostic (1.57e-1)" "unprognostic (5.22e-2)" "unprognostic (4.43e-3)" "unprognostic (2.96e-1)" "unprognostic (1.17e-2)" 25.5 5.1 0.2 2.1 0.2 1.0 9.5 0.5 0.3 10.4 0.0 4.3 16.6 4.2 0.5 6.8 3.0 0.0 22.3 0.0 0.0 4.4 13.2 2.9 2.6 0.1 0.1 56.1 133851.7 0.0 7.2 6.5 0.1 5.6 0.0 0.0 22.3 0.2 3.8 5.8 8.9 0.0 0.0 11.7 7.6 3.4 0.1 0.0 2.8 0.1 0.0 2.4 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.1 0.1 2.0 0.0 0.0 0.1 31269.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 151.9 0.0 0.0 0.0 0.1 1430.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 CTRB2 ENSG00000168928 "Chymotrypsinogen B2" Q6GPI1 16 75204103-75207161 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2443 "pancreas: 98661.0" "Cell type enriched" "Detected in some" 9 "Exocrine glandular cells: 53114.3" "Cancer enriched" "Detected in single" 1696 "pancreatic cancer: 540.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.4;U-2 OS: 5.8;U-251 MG: 1.6;U-266/84: 1.8;U-698: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (9.41e-4)" "unprognostic (2.20e-1)" "unprognostic (1.28e-2)" "unprognostic (2.10e-1)" "unprognostic (2.92e-2)" "unprognostic (2.77e-1)" "unprognostic (5.95e-2)" "unprognostic (9.56e-2)" "unprognostic (3.54e-3)" "unprognostic (7.06e-2)" "unprognostic (2.17e-1)" "unprognostic (7.57e-2)" 27.8 4.8 0.2 1.5 0.2 1.8 9.1 0.4 0.3 8.2 0.0 4.4 9.1 4.7 0.1 6.6 3.7 0.2 13.7 0.1 0.2 4.5 12.8 3.1 2.8 0.2 0.1 40.3 98661.0 0.0 5.7 5.6 0.2 11.8 0.0 0.0 16.7 0.1 3.7 5.2 6.6 0.0 0.1 7.2 8.1 3.7 0.2 0.0 3.1 0.0 0.0 2.8 4.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.8 0.0 1.6 0.0 1.8 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 108.8 2.0 0.3 0.0 1.5 0.0 0.0 0.0 53114.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.3 6.0 0.0 0.0 215.5 0.0 0.0 0.0 0.0 5324.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 30.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 CTRC "CLCR, ELA4" ENSG00000162438 "Chymotrypsin C" Q99895 1 15438442-15449242 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 3927 "pancreas: 25708.5" "Cell type enriched" "Detected in some" 9 "Exocrine glandular cells: 6566.4" "Cancer enriched" "Detected in some" 168 "pancreatic cancer: 236.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046920 Enhanced "Secreted to digestive system" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" "HPA046920: AB_2679865" "unprognostic (2.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (8.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (2.94e-2)" "unprognostic (7.60e-2)" "unprognostic (3.34e-1)" "unprognostic (2.00e-1)" "unprognostic (9.55e-11)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "unprognostic (1.50e-1)" "unprognostic (5.99e-3)" 6.5 1.2 0.2 0.2 0.2 0.7 2.9 0.7 0.3 2.7 0.2 1.2 1.1 1.3 0.1 1.9 0.8 0.0 2.3 0.3 0.1 1.2 3.5 1.0 0.3 0.1 0.1 5.6 25708.5 0.0 1.5 0.7 0.2 1.8 0.0 0.1 2.1 0.0 1.0 2.1 1.7 0.0 0.0 2.0 2.3 1.0 0.2 0.0 1.0 0.0 0.0 0.6 1.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.1 0.0 0.0 0.2 0.2 0.7 0.3 0.3 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.2 0.0 0.5 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 17.3 0.0 0.6 1.0 0.7 0.0 0.0 0.2 6566.4 0.1 0.2 0.0 2.1 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.9 0.0 0.0 1.1 1.8 0.0 24.3 0.0 1.0 0.0 0.0 673.8 0.0 0.0 0.1 0.3 0.4 0.1 0.0 0.0 0.0 1.3 3.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.3 CTRL ENSG00000141086 "Chymotrypsin like" P40313 16 67927640-67932365 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1154 "pancreas: 7481.6" "Group enriched" "Detected in some" 20 "Exocrine glandular cells: 224.2;Pancreatic endocrine cells: 58.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034504, HPA034505" Enhanced "Secreted to digestive system" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "HPA034504: AB_2674196, HPA034505: AB_10602212" "unprognostic (3.03e-5)" "unprognostic (3.53e-3)" "unprognostic (3.46e-2)" "unprognostic (1.37e-1)" "unprognostic (9.66e-2)" "unprognostic (2.00e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (6.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.88e-1)" "unprognostic (3.20e-4)" "unprognostic (6.69e-2)" "unprognostic (2.79e-1)" "unprognostic (2.63e-1)" "unprognostic (1.29e-3)" 1.2 0.7 2.9 1.1 3.1 6.1 0.9 3.8 4.2 1.1 2.1 0.8 1.8 0.6 0.2 0.5 0.7 0.7 1.7 3.0 2.8 0.8 1.0 1.7 2.5 3.5 3.0 6.4 7481.6 0.0 1.7 0.7 3.7 1.2 0.5 0.3 1.1 0.2 0.6 1.0 1.7 0.4 2.8 3.5 1.0 0.6 3.3 1.9 0.7 0.7 1.0 0.7 0.7 3.5 0.4 2.1 0.6 0.2 0.1 0.0 0.9 0.3 0.4 0.7 1.0 1.9 1.0 0.5 0.3 0.4 0.6 0.7 4.1 0.7 2.0 0.8 4.6 0.5 0.9 1.9 0.2 0.3 1.4 0.7 0.1 2.5 0.7 0.3 0.0 1.0 1.0 1.1 0.3 0.7 0.4 2.2 4.1 1.1 1.9 2.0 0.3 3.1 0.0 0.8 1.9 1.1 0.7 0.7 0.4 0.4 0.9 2.5 0.9 0.1 1.4 0.2 1.0 3.8 1.7 2.2 0.1 0.7 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.1 0.1 0.0 0.0 2.9 3.1 3.8 4.2 3.0 2.8 3.5 3.0 3.7 2.8 3.3 3.5 0.6 0.0 0.0 1.6 0.2 0.5 0.0 0.0 2.2 0.0 0.2 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.3 0.8 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 1.3 224.2 0.0 0.5 1.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 1.7 0.4 2.0 1.2 0.3 0.0 0.0 0.5 0.0 1.0 2.1 0.0 0.0 0.5 1.6 58.5 1.4 0.0 0.2 0.1 0.3 0.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.3 0.0 0.6 6.9 0.5 0.1 CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 368.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 445.6;Proximal enterocytes: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 856.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068, HPA072487" Enhanced Enhanced Vesicles "Intracellular and membrane" NA NA 28000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "CAB024930: , HPA031068: AB_10601205, HPA072487: " "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" 80.4 368.3 56.8 75.3 58.1 75.6 61.9 63.6 65.6 47.6 96.0 178.6 100.9 55.1 39.0 60.4 39.3 89.7 97.2 59.7 63.8 188.1 95.7 90.9 61.6 62.6 59.1 62.2 52.9 104.4 43.8 76.4 61.4 38.5 170.4 44.0 61.3 48.4 56.0 95.2 109.2 67.3 59.4 108.5 63.3 33.5 70.2 23.0 47.4 61.7 58.8 82.8 49.2 68.4 111.9 114.1 17.6 89.2 856.5 438.6 47.0 150.3 424.0 169.6 217.5 214.4 291.8 24.1 176.2 299.9 638.1 168.6 55.9 105.6 95.7 47.6 53.6 54.3 53.4 375.9 187.3 98.0 240.9 349.0 123.6 107.9 22.5 421.9 190.1 28.2 61.0 355.1 186.9 232.1 25.8 82.4 19.4 172.6 272.1 37.8 107.3 135.7 138.2 96.7 36.9 37.8 263.2 450.3 444.4 51.5 108.5 141.8 172.5 335.0 76.2 178.9 123.7 162.1 238.5 15.7 599.3 128.6 142.4 480.7 305.9 530.5 44.9 168.8 185.5 42.0 75.6 78.3 102.4 25.7 26.6 39.8 152.4 81.2 120.1 40.6 155.4 378.1 56.8 58.1 63.6 65.6 59.7 63.8 62.6 59.1 61.4 59.4 70.2 68.4 53.7 35.3 32.6 26.1 38.2 24.2 38.9 88.8 17.6 58.4 18.4 15.9 12.6 65.8 64.1 71.7 60.5 104.1 27.5 445.6 39.2 246.0 3.3 22.3 39.5 56.0 54.0 22.1 20.4 166.4 109.2 86.8 29.6 62.4 9.5 50.8 102.1 67.9 297.1 47.1 25.2 74.5 95.6 177.1 25.1 4.8 32.9 273.1 112.1 12.2 135.6 86.6 37.0 7.1 10.2 135.0 216.0 27.4 41.9 18.6 301.8 245.8 34.2 46.1 26.3 33.7 54.5 15.3 31.9 24.0 22.9 144.1 49.1 91.3 113.9 36.2 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88265069-88359684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 900.7;Club cells: 471.8;Hofbauer cells: 1100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" No No 19000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB025364: , HPA066610: AB_2685694, HPA068434: AB_2685989" "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (9.30e-5)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-2)" "unprognostic (3.35e-1)" "prognostic favorable (4.80e-4)" "unprognostic (2.93e-1)" "unprognostic (4.35e-2)" "unprognostic (8.10e-2)" "unprognostic (4.07e-2)" 173.2 60.7 9.9 185.1 9.6 71.7 63.4 11.1 24.9 77.9 14.2 143.1 121.0 43.9 28.5 63.3 54.0 182.0 38.5 9.5 10.1 234.7 82.0 272.6 243.7 14.0 11.9 22.1 52.2 42.4 39.3 253.3 13.3 26.0 191.5 3.7 131.6 28.9 18.8 29.6 128.8 88.9 11.5 197.2 73.6 22.8 19.5 63.7 43.6 31.9 140.6 176.3 43.3 21.3 80.3 75.9 27.6 69.9 103.7 286.1 218.4 626.5 1078.4 372.8 270.3 194.7 361.3 117.3 278.9 365.2 84.3 133.6 50.4 269.2 341.9 204.7 82.8 144.5 188.0 233.5 140.2 188.9 108.7 419.1 198.8 284.5 697.4 302.1 377.6 122.3 155.3 145.4 54.8 14.8 89.1 295.1 172.2 551.5 244.9 113.6 30.7 227.0 451.3 106.6 8.8 66.8 81.2 114.9 80.6 185.4 27.9 152.7 149.3 23.5 190.5 156.8 364.6 61.9 81.0 122.9 56.8 435.8 122.4 85.5 203.8 309.7 230.1 415.6 194.9 47.2 99.6 198.2 209.9 26.3 49.5 115.3 215.0 200.5 582.9 425.0 162.7 243.3 9.9 9.6 11.1 24.9 9.5 10.1 14.0 11.9 13.3 11.5 19.5 21.3 78.6 22.4 88.1 0.3 40.8 30.1 7.3 900.7 33.6 1.5 15.9 14.6 4.4 52.9 471.8 40.5 0.0 414.1 330.6 37.9 29.4 29.8 1.6 13.4 135.6 94.8 11.4 29.7 3.0 90.6 159.2 114.4 39.8 21.2 75.3 25.5 26.4 15.8 1100.6 0.0 8.2 19.4 158.7 344.7 200.7 7.9 198.5 391.7 48.0 61.8 185.4 0.5 299.7 13.6 0.4 44.8 72.3 25.6 78.5 8.5 20.2 166.4 93.7 0.8 59.2 4.4 150.8 3.0 11.1 43.3 27.1 227.3 170.6 286.7 44.9 16.1 CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1475.9;Hofbauer cells: 3763.5;Macrophages: 1512.6;Proximal enterocytes: 1699.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 2596.6;hTERT-RPE1: 2780.1;SK-BR-3: 2488.5" "CAB000109, HPA003001" Supported "Secreted to blood" NA NA 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" 318.6 734.6 147.0 204.9 181.9 499.0 244.0 186.0 156.5 270.8 672.7 298.0 387.6 170.7 82.8 319.4 171.6 438.4 444.1 187.8 223.6 691.6 464.8 539.6 241.0 247.6 206.6 130.7 284.8 137.3 131.5 180.7 228.6 138.2 153.4 48.3 422.1 231.7 590.3 340.9 398.3 105.0 188.9 442.0 287.2 88.9 334.4 78.1 182.1 178.2 123.1 296.4 307.5 367.1 204.6 578.9 51.4 246.2 586.5 206.3 112.1 149.4 362.2 161.8 182.8 147.5 2596.6 49.2 376.8 285.8 1265.6 1072.2 63.7 142.6 35.8 206.7 222.9 70.4 92.5 196.5 736.2 171.4 787.7 350.9 621.6 82.5 136.9 2780.1 128.2 62.1 89.2 267.6 263.3 832.6 47.0 110.9 153.1 719.7 247.9 62.5 72.5 191.2 586.6 610.8 84.2 94.8 173.3 2488.5 535.0 68.6 1022.8 232.6 170.3 556.8 92.9 79.0 216.7 432.0 382.3 26.8 867.7 468.6 509.6 211.2 578.7 170.1 156.5 309.9 90.6 28.8 72.1 110.3 144.5 18.8 82.5 107.4 319.5 192.3 265.2 120.3 89.2 489.1 147.0 181.9 186.0 156.5 187.8 223.6 247.6 206.6 228.6 188.9 334.4 367.1 139.3 112.2 228.6 48.3 62.8 72.0 223.5 473.2 71.7 168.6 108.9 113.8 251.9 314.5 459.5 548.1 110.5 211.7 156.1 1475.9 109.5 911.4 3.3 118.1 67.4 128.3 159.6 132.6 18.3 370.1 165.0 157.0 237.5 203.4 474.3 119.4 695.7 678.9 3763.5 264.2 25.2 418.2 498.5 1187.8 67.5 14.6 108.4 1512.6 227.7 20.6 382.6 179.0 256.4 27.2 42.2 392.3 832.5 128.2 122.5 111.7 1699.4 311.8 270.3 102.1 111.7 70.7 135.2 26.6 63.5 141.2 82.1 471.3 155.0 96.0 399.1 357.8 CTSE ENSG00000196188 "Cathepsin E" P14091 1 206008535-206023909 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 1168.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 105.8;Exocrine glandular cells: 262.8;Gastric mucus-secreting cells: 553.5;Pancreatic endocrine cells: 260.0;Paneth cells: 208.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 297.4;stomach cancer: 200.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 46 "OE19: 1799.1" "Not detected" "Not detected" "HPA012674, HPA012940, CAB032687" Enhanced Approved Vesicles "Intracellular and membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB032687: AB_637901, HPA012674: , HPA012940: AB_2668773" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-2)" "unprognostic (2.72e-2)" "unprognostic (1.35e-2)" "unprognostic (2.52e-3)" "unprognostic (1.45e-1)" "unprognostic (3.29e-2)" "unprognostic (2.87e-2)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "unprognostic (6.37e-3)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (2.61e-2)" "prognostic favorable (5.26e-5)" 0.3 0.0 0.1 9.5 0.1 30.0 0.0 0.5 0.3 0.0 0.1 15.3 229.8 0.3 1.7 0.8 1.1 15.0 0.3 0.1 0.1 0.2 0.2 49.7 0.5 0.3 0.1 0.1 3.7 0.0 1.1 1.3 0.3 0.2 25.7 0.1 0.0 1.6 0.0 0.1 55.5 0.3 0.1 0.6 1168.3 0.1 0.3 0.5 8.9 0.0 10.7 5.8 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.8 0.8 0.0 3.8 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.2 2.4 0.0 1.0 3.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.8 1.5 0.7 1799.1 0.1 0.4 0.0 0.8 0.7 39.4 0.2 0.5 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.2 0.5 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.6 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.5 0.3 0.1 0.1 0.3 0.1 0.3 0.1 0.3 0.5 0.0 105.8 27.9 0.0 0.6 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.5 10.0 42.3 0.0 0.0 0.0 0.0 34.1 0.0 52.0 0.0 0.3 0.0 0.3 2.4 60.6 0.0 262.8 0.1 14.7 553.5 0.6 0.0 0.0 0.0 0.2 0.2 0.0 0.0 21.1 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.6 0.0 0.0 0.0 0.1 260.0 208.9 0.0 0.7 0.1 4.0 0.1 7.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 10.4 0.4 CTSF "CATSF, CLN13" ENSG00000174080 "Cathepsin F" Q9UBX1 11 66563464-66568879 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 320.9;Muller glia cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SiHa: 23.1;SK-MEL-30: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002141, HPA031431" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 5800000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum, Plasma membrane" "CAB002141: AB_563471, HPA031431: " "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (7.22e-3)" "unprognostic (2.25e-2)" "unprognostic (6.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.76e-2)" "unprognostic (3.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.69e-2)" "unprognostic (9.12e-2)" "prognostic favorable (8.92e-7)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (2.42e-1)" 57.8 70.0 68.1 0.8 76.3 0.3 62.2 74.5 74.0 78.8 90.2 76.7 3.0 89.2 21.9 15.6 70.8 10.0 100.2 63.2 74.2 46.9 66.0 32.9 3.6 75.0 70.3 99.1 31.7 20.0 43.3 3.8 68.4 53.5 3.5 26.2 55.7 17.1 91.9 44.4 29.5 12.2 77.2 25.0 54.3 109.7 71.0 3.0 40.6 27.6 3.0 56.6 58.7 86.6 0.0 17.0 3.1 5.4 14.2 8.6 3.4 13.0 11.4 6.3 2.3 0.0 2.2 0.0 21.3 10.4 0.0 1.2 6.8 2.6 4.8 3.7 0.0 0.5 7.0 0.0 9.9 0.3 4.4 22.3 9.1 0.8 1.6 13.7 3.8 2.0 5.4 1.6 5.2 4.6 0.1 1.7 0.9 3.7 9.7 0.0 0.0 1.5 7.1 0.3 4.3 6.9 23.1 0.3 59.5 0.3 7.4 0.6 3.3 1.8 2.9 1.5 1.2 21.2 0.2 0.0 2.2 0.0 2.9 0.0 0.4 0.3 3.9 0.6 4.1 1.5 3.5 4.6 0.6 1.4 6.4 4.1 0.1 4.6 0.2 0.9 1.3 2.2 68.1 76.3 74.5 74.0 63.2 74.2 75.0 70.3 68.4 77.2 71.0 86.6 36.6 12.8 15.6 31.3 5.9 39.8 62.4 8.5 37.5 107.9 45.3 80.6 57.9 41.5 7.4 36.8 41.7 31.6 9.6 0.6 15.6 13.1 163.3 1.7 22.8 27.2 12.0 11.4 26.5 7.5 9.5 118.1 8.2 5.3 9.5 52.1 56.0 67.8 14.9 134.6 31.3 3.1 18.3 21.5 32.8 320.9 145.7 13.1 156.5 12.2 3.1 196.6 17.5 21.6 29.4 5.9 3.2 121.9 12.9 50.5 1.3 44.7 3.3 77.9 78.9 62.0 45.9 169.6 43.3 3.6 25.3 23.7 9.5 30.7 4.3 32.9 CTSG CG ENSG00000100448 "Cathepsin G" P08311 14 24573518-24576250 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 154 "bone marrow: 5352.9" "Cell type enriched" "Detected in some" 16 "granulocytes: 534.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "THP-1: 8681.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000110, HPA047737" Enhanced "Intracellular and membrane" NA NA 330000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "CAB000110: , HPA047737: AB_2680140" "unprognostic (1.67e-1)" "unprognostic (2.57e-2)" "unprognostic (6.92e-2)" "unprognostic (1.08e-1)" "prognostic favorable (1.57e-4)" "unprognostic (4.05e-2)" "unprognostic (4.13e-2)" "unprognostic (3.06e-1)" "unprognostic (2.42e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" "unprognostic (1.63e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.91e-4)" 23.4 0.1 0.0 13.5 0.0 5352.9 25.4 0.0 0.0 16.6 0.0 25.5 5.8 9.6 10.2 22.1 2.7 25.9 3.7 0.0 0.0 2.3 3.6 11.6 6.5 0.0 0.0 0.5 3.5 1.5 1.0 2.9 0.0 3.7 25.5 0.0 11.5 4.8 1.8 28.0 18.1 7.7 0.0 16.9 4.9 3.2 0.0 26.0 0.8 7.6 6.0 34.8 4.1 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 303.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 33.2 0.0 0.1 0.0 0.0 3.6 41.5 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 1.2 0.0 3.6 0.0 0.0 8681.4 0.0 0.0 0.3 0.0 5.3 0.0 0.8 2.8 0.0 1287.5 0.1 0.0 6.0 0.0 1.1 1.0 0.0 0.0 0.9 3.4 5.4 0.0 0.0 1.7 7.3 5.0 0.0 6.5 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 12.8 33.3 0.0 0.2 6.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.3 0.0 0.0 2.4 0.0 1.3 0.0 0.0 0.1 1.0 0.0 0.0 534.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.6 11.1 9.1 0.0 1.5 5.4 0.0 1.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.7 0.0 0.0 0.2 1.3 0.3 1.7 0.0 4.0 0.0 5.1 0.0 0.4 0.0 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 349.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1569.9;Proximal tubular cells: 523.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 208.5;intermediate monocyte: 137.7;memory B-cell: 83.3;myeloid DC: 183.6;naive B-cell: 56.0;non-classical monocyte: 94.8" "Group enriched" "Detected in all" 5 "B-cells: 83.3;dendritic cells: 183.6;monocytes: 208.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 306.4;HaCaT: 228.2;HDLM-2: 183.0;OE19: 197.4;RT4: 362.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" NA NA 8700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 34.3 36.4 29.4 100.6 30.2 36.9 48.8 29.9 47.1 112.8 31.4 32.5 77.8 46.7 26.8 37.9 57.6 104.6 51.3 29.6 32.9 238.2 89.5 349.6 191.8 30.8 31.4 30.0 75.5 77.6 10.1 25.7 31.5 59.7 27.3 4.7 63.0 70.7 16.3 48.4 56.7 43.1 30.7 51.8 93.9 10.1 32.7 51.8 27.7 37.7 131.3 202.2 30.6 32.4 122.0 10.0 1.2 30.5 5.4 0.5 20.3 8.6 3.0 13.9 7.0 17.6 306.4 34.6 12.6 0.0 13.5 228.2 5.2 52.6 10.1 183.0 0.4 3.0 1.3 38.4 12.1 0.4 7.1 5.6 10.7 0.2 0.0 59.4 1.0 5.9 76.0 0.0 17.9 2.8 32.6 87.8 8.9 197.4 4.9 0.3 0.4 5.9 49.9 362.1 2.6 5.2 41.5 27.8 75.4 10.1 12.5 48.0 16.4 0.2 6.2 0.0 5.3 0.8 92.4 19.5 0.1 89.2 12.3 0.0 208.5 2.0 7.6 137.7 29.7 83.3 20.5 7.4 183.6 56.0 1.8 3.8 8.7 3.2 94.8 22.9 18.3 147.5 29.4 30.2 29.9 47.1 29.6 32.9 30.8 31.4 31.5 30.7 32.7 32.4 169.8 237.2 1569.9 59.1 127.4 24.2 280.7 363.9 30.1 1.3 45.5 41.7 26.2 358.9 258.7 367.8 4.2 19.8 8.1 9.1 84.1 225.0 25.3 67.0 86.0 124.5 9.1 3.0 2.2 142.0 39.6 53.8 106.0 42.8 32.8 2.7 14.3 115.5 256.7 0.0 2.9 18.6 101.7 177.8 259.6 22.6 73.0 350.4 80.0 15.9 360.9 22.6 5.2 1.5 1.1 84.6 16.0 6.0 155.8 112.0 153.0 523.2 261.6 6.6 19.7 4.5 22.3 12.3 56.4 41.6 18.6 23.4 29.4 17.8 40.1 340.4 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 563.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1081.6;Extravillous trophoblasts: 1012.3;Hepatic stellate cells: 580.4;Hofbauer cells: 1105.7;Macrophages: 537.2;Syncytiotrophoblasts: 1543.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.1;non-classical monocyte: 195.2" "Lineage enriched" "Detected in many" 12 "monocytes: 195.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 2305.0;HSkMC: 1061.0" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 17000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 232.4 86.6 49.2 136.0 55.4 84.8 110.0 52.9 67.5 69.5 67.9 110.3 39.7 108.1 81.6 33.3 108.4 85.0 112.5 47.0 52.3 207.3 333.5 154.9 101.1 54.4 54.0 96.4 61.9 151.1 69.5 563.6 57.5 68.2 58.8 32.3 77.6 91.7 71.9 39.8 57.1 125.2 52.4 124.4 71.4 80.1 112.2 33.0 76.1 79.8 49.4 209.8 48.0 59.6 88.1 423.0 32.6 55.3 514.0 2305.0 198.4 267.2 781.8 232.2 300.6 43.0 86.3 0.0 128.9 355.4 754.0 67.5 49.8 86.0 198.4 1.9 37.8 18.1 111.2 105.1 352.6 0.1 51.4 1061.0 138.9 373.7 134.9 186.6 194.9 0.0 162.5 0.7 326.6 115.6 0.5 9.9 67.7 128.6 77.5 21.6 21.5 0.6 158.6 39.0 42.8 50.6 62.1 133.5 312.3 177.9 14.5 97.9 296.9 190.8 104.7 750.6 125.9 18.5 84.1 0.9 692.6 0.2 67.9 0.3 13.5 0.6 0.3 128.1 0.0 0.0 6.6 0.1 7.9 0.1 16.7 1.3 0.5 0.2 195.2 0.3 1.7 10.1 49.2 55.4 52.9 67.5 47.0 52.3 54.4 54.0 57.5 52.4 112.2 59.6 86.1 41.7 52.9 15.3 11.2 37.7 82.1 58.0 15.4 43.8 12.2 33.4 96.8 87.2 46.4 75.4 18.8 1081.6 0.3 16.3 27.4 91.8 5.3 48.1 119.9 110.0 11.5 251.2 18.6 93.4 1012.3 261.7 10.2 27.6 29.7 63.6 580.4 122.6 1105.7 13.5 24.0 8.5 20.3 206.9 105.4 17.4 156.9 537.2 64.0 14.0 16.2 79.5 0.0 17.6 31.7 67.2 5.6 187.3 1.9 34.5 8.0 138.3 67.3 45.4 92.1 176.9 136.3 207.4 60.5 6.8 34.0 1543.6 10.8 30.8 11.7 44.8 CTSO CTSO1 ENSG00000256043 "Cathepsin O" P43234 4 155921580-155953912 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 37.1;HSkMC: 44.6;Karpas-707: 85.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002041 Approved "Intracellular and membrane" NA NA 25000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA002041: AB_1078408" "unprognostic (3.96e-3)" "unprognostic (1.62e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (9.10e-3)" "unprognostic (2.55e-1)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (6.62e-2)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.55e-2)" "unprognostic (4.87e-3)" "unprognostic (4.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" 19.1 31.5 8.0 17.8 8.0 5.0 31.9 6.2 11.8 36.7 7.9 19.6 32.8 37.2 36.1 16.7 36.9 40.7 20.2 7.8 7.6 34.5 98.8 36.8 24.5 7.1 7.5 28.0 19.9 24.5 9.6 41.2 6.9 29.8 23.2 5.2 22.1 32.2 6.7 10.0 34.0 30.7 7.0 39.7 15.5 9.4 7.4 14.1 34.5 17.8 17.9 28.0 15.4 7.6 0.8 0.6 4.1 3.7 17.3 37.1 0.2 1.6 18.3 3.3 5.7 0.4 14.4 0.2 1.2 6.8 1.2 0.1 0.2 0.1 2.6 1.6 0.1 0.4 0.5 0.2 18.1 1.4 0.2 44.6 3.5 2.2 1.8 25.6 3.5 0.7 0.3 85.8 11.7 0.7 1.1 0.4 0.7 0.6 0.7 4.8 0.5 1.0 16.8 7.5 0.5 4.3 2.4 9.3 2.3 2.0 4.2 2.6 3.0 13.3 0.7 0.4 2.3 8.3 0.2 0.2 24.4 0.3 18.6 5.3 0.9 0.6 1.2 0.7 3.0 1.2 1.4 0.8 0.4 1.5 1.6 2.0 0.7 3.0 0.9 1.0 3.3 1.4 8.0 8.0 6.2 11.8 7.8 7.6 7.1 7.5 6.9 7.0 7.4 7.6 29.3 38.5 20.8 15.0 19.9 10.5 13.1 11.3 12.0 10.4 20.1 13.0 5.0 44.3 14.3 25.8 2.1 20.5 19.6 15.6 13.7 24.6 0.4 20.9 34.6 28.2 6.7 8.6 1.7 20.7 7.7 51.5 8.6 27.3 8.8 25.0 43.2 58.1 16.3 5.0 1.7 7.9 8.2 29.2 23.7 1.5 30.4 21.4 30.2 7.5 26.5 17.0 22.6 36.7 5.4 12.7 6.3 25.2 7.0 17.5 21.1 10.7 14.5 1.9 19.7 34.0 24.6 0.3 2.1 5.9 9.1 10.5 14.5 14.3 6.6 9.5 CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730079-150765957 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 137.0;lymphoid tissue: 164.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 698.6;Kupffer cells: 2230.8;Macrophages: 1316.2;monocytes: 2312.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 2483.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 81.6;HMC-1: 187.5;U-698: 387.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" NA NA 23000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" 40.0 16.7 4.0 87.8 4.5 137.0 20.3 4.8 7.1 9.4 8.0 83.6 60.2 7.8 5.7 16.5 17.8 29.1 10.6 3.4 5.5 9.3 40.4 88.4 71.7 11.8 8.0 4.9 11.3 2.3 4.7 23.6 11.2 9.1 59.4 3.4 23.9 7.3 4.1 7.1 64.6 16.3 7.7 164.8 42.6 3.8 10.4 20.1 11.5 9.0 38.5 42.9 10.0 16.1 3.7 10.9 0.2 0.3 1.2 1.4 0.7 0.4 8.6 0.9 1.3 1.2 81.6 44.3 5.7 1.2 15.3 2.1 0.2 0.7 0.5 26.9 0.2 29.0 1.1 0.8 0.2 33.6 187.5 2.6 0.1 6.6 1.5 0.5 6.3 0.6 3.4 45.0 2.4 0.3 0.4 22.5 0.2 0.1 0.3 14.9 4.6 49.8 10.7 8.7 0.3 0.4 1.1 2.3 0.8 0.3 0.4 49.8 9.1 6.2 1.3 0.8 1.2 27.8 2.2 387.3 28.5 35.2 2.3 20.9 2483.4 218.0 41.3 1735.3 51.1 139.5 46.6 50.9 571.0 138.8 45.0 40.8 1022.2 41.8 1655.1 106.8 77.4 2577.6 4.0 4.5 4.8 7.1 3.4 5.5 11.8 8.0 11.2 7.7 10.4 16.1 37.6 109.0 158.7 1.6 255.3 17.0 31.3 72.0 4.6 2.3 21.0 8.9 5.3 74.4 143.4 42.3 12.5 3.7 198.0 549.2 0.0 183.6 6.6 126.9 8.6 44.1 42.4 22.5 10.3 177.0 5.7 34.4 71.9 39.0 106.8 9.5 60.3 30.6 698.6 0.0 9.5 205.7 73.2 2230.8 316.4 3.0 5.3 1316.2 56.9 27.2 2312.9 0.5 137.0 0.5 0.9 200.9 466.5 2.2 121.4 20.6 210.8 4.7 488.9 4.9 19.7 5.6 13.3 0.2 0.5 12.4 15.5 6.2 108.9 66.0 237.8 113.3 CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029677-97156556 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 643.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 63.7;Cytotrophoblasts: 122.3;Extravillous trophoblasts: 153.0;Granulosa cells: 54.2;Syncytiotrophoblasts: 67.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.1" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.1" "Group enriched" "Detected in many" 8 "BEWO: 592.6;SuSa: 739.0" "Low region specificity" "Detected in all" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (2.40e-1)" "unprognostic (2.74e-2)" "unprognostic (1.50e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.29e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (2.83e-5)" "unprognostic (7.04e-3)" "unprognostic (6.06e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.86e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-2)" "unprognostic (1.33e-1)" "unprognostic (3.04e-3)" "prognostic unfavorable (2.39e-4)" 0.2 0.2 0.6 0.3 0.7 0.3 5.8 0.8 1.6 43.1 0.8 2.9 1.1 2.8 1.7 19.8 1.3 0.5 0.1 0.6 0.5 21.3 0.2 0.9 0.1 0.7 0.6 0.2 2.1 1.4 1.5 16.8 0.6 0.7 3.2 17.2 9.4 0.1 0.7 52.5 0.4 0.8 0.5 0.2 2.8 65.8 0.6 643.6 1.3 0.1 6.0 0.4 20.1 1.0 37.1 5.2 12.1 33.1 0.6 0.0 592.6 0.5 0.0 7.1 4.7 81.0 37.7 0.3 2.8 0.5 50.5 67.2 58.8 43.9 9.7 0.1 4.4 0.8 1.9 3.1 0.2 0.1 3.3 0.0 9.2 1.5 0.8 0.9 2.4 8.5 0.5 0.2 14.4 15.2 0.9 0.3 76.2 78.9 10.7 0.0 27.3 0.1 11.4 3.7 2.4 3.6 39.1 13.1 13.2 739.0 21.1 3.2 0.0 1.0 23.6 0.2 3.5 5.7 20.6 0.8 1.6 0.4 4.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.1 0.0 0.2 3.3 0.0 15.1 0.0 0.1 0.6 0.7 0.8 1.6 0.6 0.5 0.7 0.6 0.6 0.5 0.6 1.0 0.9 0.0 1.1 0.3 0.9 30.3 13.0 63.7 19.9 4.6 13.1 9.9 1.3 0.0 17.4 1.8 10.4 122.3 6.9 4.7 1.9 1.8 2.6 15.0 2.9 1.8 1.8 0.0 0.6 0.8 153.0 3.2 0.0 24.0 0.0 54.2 0.4 0.0 13.6 0.0 0.9 1.5 10.2 0.8 3.0 8.2 4.1 2.4 0.0 0.0 0.2 6.5 0.0 0.0 3.5 0.5 10.5 1.2 0.0 8.1 0.1 22.1 4.2 36.6 6.6 1.4 3.6 46.7 33.7 8.2 11.9 67.3 0.5 0.7 4.2 8.4 CTSW ENSG00000172543 "Cathepsin W" P56202 11 65879809-65883741 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 116.3;lymphoid tissue: 42.4" "Group enriched" "Detected in many" 9 "dendritic cells: 717.8;NK-cells: 867.2;T-cells: 352.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 8 "gdT-cell: 1376.3;MAIT T-cell: 869.4;memory CD8 T-cell: 892.8;naive CD8 T-cell: 636.3;NK-cell: 2276.1" "Group enriched" "Detected in all" 39 "NK-cells: 2276.1;T-cells: 1376.3" "Group enriched" "Detected in some" 22 "HEL: 156.7;NB-4: 363.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB016345, HPA066903" Enhanced "Intracellular and membrane" NA NA 270000 "Cluster 48: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB016345: AB_626813, HPA066903: " "prognostic favorable (3.06e-4)" "unprognostic (2.06e-2)" "unprognostic (2.71e-2)" "prognostic favorable (8.36e-6)" "unprognostic (1.21e-1)" "prognostic favorable (9.89e-4)" "unprognostic (5.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (5.14e-3)" "unprognostic (2.83e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (8.84e-6)" "unprognostic (3.86e-2)" "unprognostic (3.78e-1)" "unprognostic (1.26e-1)" "unprognostic (4.01e-3)" 5.1 2.9 0.8 12.9 0.9 116.3 3.7 1.8 1.6 2.6 0.6 5.6 6.1 6.7 2.8 3.1 4.0 6.2 2.9 0.8 0.9 2.1 6.5 24.0 29.5 1.6 0.7 2.4 1.8 0.5 1.1 3.3 1.2 2.1 6.3 0.0 9.1 3.9 1.3 2.7 6.1 2.7 1.2 42.4 8.3 1.2 1.1 7.8 3.2 0.4 13.9 8.6 2.5 1.1 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.0 156.7 0.3 0.0 0.0 11.8 0.4 0.0 0.0 0.0 0.1 0.0 0.0 5.0 0.0 9.1 0.2 0.2 1.9 363.4 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.0 0.0 5.6 0.1 0.0 0.1 0.4 0.1 0.3 0.5 0.0 0.2 9.9 0.3 46.4 3.4 4.8 1376.3 4.0 869.4 5.1 145.3 892.8 37.6 3.7 86.0 636.3 25.7 2276.1 5.4 23.3 23.7 809.3 0.8 0.9 1.8 1.6 0.8 0.9 1.6 0.7 1.2 1.2 1.1 1.1 5.1 0.0 4.2 0.0 9.7 4.6 0.4 0.0 1.8 0.0 2.3 2.2 0.4 2.8 1.4 0.0 0.0 0.4 717.8 0.3 0.0 0.3 2.0 0.9 0.9 1.9 0.0 44.1 0.0 0.0 0.2 4.0 12.8 1.1 71.7 0.1 5.7 1.6 1.9 0.0 0.0 0.2 0.0 5.6 34.1 11.1 0.0 9.9 17.8 0.0 6.1 0.0 867.2 0.0 0.2 0.0 0.0 0.0 57.7 0.3 0.0 1.1 0.8 0.0 0.0 1.6 1.9 0.3 1.2 0.8 6.3 0.3 352.6 0.1 0.3 0.3 CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58985686-59008238 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1078.9;Langerhans cells: 983.5;Macrophages: 652.3;monocytes: 723.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 542.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "CAB025114: , HPA049876: AB_2680927, HPA053504: AB_2682172" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" 178.1 117.8 18.9 208.8 21.8 99.8 137.0 20.5 32.0 92.1 59.6 173.8 215.4 87.3 13.4 53.1 88.9 89.4 152.6 15.3 33.9 125.6 356.4 233.3 271.5 31.6 23.5 71.0 89.4 91.8 112.5 118.7 27.9 87.8 77.1 4.1 181.0 66.3 58.7 58.5 226.0 97.9 26.2 234.4 88.2 24.6 47.2 57.1 122.3 54.6 91.3 146.3 69.0 45.4 205.4 139.8 1.1 1.1 114.2 124.2 106.5 291.0 225.4 187.4 152.3 231.6 324.6 96.5 213.9 542.1 0.5 160.1 51.4 257.5 30.2 362.1 13.6 80.3 169.0 0.8 137.3 9.0 331.0 130.9 127.8 83.1 62.4 34.8 281.3 1.1 74.0 48.7 90.0 1.1 1.3 70.6 11.5 43.5 158.2 2.9 0.4 135.7 86.3 25.5 2.7 1.7 222.4 258.4 0.8 19.5 131.9 148.4 420.5 1.4 161.8 209.0 2.0 253.7 172.0 18.2 2.8 207.9 0.4 1.2 1.5 1.6 0.6 1.4 0.4 1.1 0.6 0.4 1.1 1.4 0.7 0.8 1.6 0.5 2.9 1.8 0.3 0.7 18.9 21.8 20.5 32.0 15.3 33.9 31.6 23.5 27.9 26.2 47.2 45.4 132.1 16.0 5.3 5.9 119.8 50.3 64.5 33.8 24.5 6.7 67.4 99.6 21.7 62.9 14.1 71.7 0.0 38.2 104.8 303.6 23.5 176.0 3.5 52.9 47.7 82.2 27.1 63.3 5.3 42.4 104.8 71.5 19.4 71.3 10.8 68.4 62.8 363.0 1078.9 11.8 3.0 56.6 26.4 334.0 983.5 6.0 13.1 652.3 101.4 23.4 723.6 58.6 21.6 2.5 2.5 82.6 217.5 13.9 96.3 50.6 339.8 90.0 18.8 5.0 46.0 67.5 74.5 3.7 4.8 14.5 41.5 41.3 33.4 3.3 99.7 52.7 CUBN "gp280, IFCR, MGA1" ENSG00000107611 Cubilin O60494 10 16823966-17129811 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Protein transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 140.4" "Group enriched" "Detected in many" 7 "Proximal enterocytes: 257.7;Proximal tubular cells: 325.0" "Cancer enriched" "Detected in some" 15 "renal cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 14.8;ASC TERT1: 3.0;SK-MEL-30: 2.8;WM-115: 5.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004133, HPA043854" Enhanced "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA004133: AB_2732398, HPA043854: AB_2732510" "unprognostic (1.75e-1)" "unprognostic (2.35e-1)" "unprognostic (2.12e-3)" "unprognostic (8.61e-4)" "unprognostic (9.54e-2)" "unprognostic (2.78e-2)" "unprognostic (2.88e-2)" "unprognostic (7.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.47e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.24e-3)" "unprognostic (1.97e-1)" "unprognostic (2.00e-1)" "unprognostic (1.93e-1)" 0.7 0.8 0.8 0.4 0.9 0.4 0.8 0.8 0.7 1.2 1.3 0.5 0.2 0.7 3.1 0.2 2.1 0.3 0.6 0.8 0.8 140.4 0.1 0.6 0.8 2.5 1.7 2.5 0.5 0.6 2.2 2.6 2.4 1.1 0.2 3.0 0.7 0.4 0.3 0.8 28.0 0.4 1.7 0.9 0.4 2.0 1.0 1.7 3.8 0.5 0.7 0.4 0.7 0.6 0.0 0.0 1.5 14.8 0.5 3.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.8 1.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.6 1.5 0.6 0.1 0.2 0.2 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.3 0.0 0.0 2.8 0.1 0.0 0.1 1.6 0.1 0.2 0.3 0.1 0.5 0.0 0.0 0.4 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.9 0.8 0.7 0.8 0.8 2.5 1.7 2.4 1.7 1.0 0.6 3.2 0.0 1.5 23.8 3.7 0.5 0.4 0.2 0.6 2.9 0.6 0.6 1.7 0.0 3.2 5.5 2.1 0.0 3.3 0.1 13.7 0.0 37.3 3.1 2.2 5.7 0.0 0.0 8.4 0.2 0.0 2.3 0.0 2.2 0.0 2.2 1.4 0.0 0.1 0.0 9.0 3.7 0.0 0.3 0.4 31.8 2.8 3.1 7.2 7.5 0.1 6.5 1.0 9.0 5.5 0.1 5.0 1.2 1.6 0.4 257.7 325.0 3.5 4.0 0.0 19.0 1.6 1.1 0.9 0.1 0.9 0.1 2.9 1.2 1.2 0.2 CUTA "ACHAP, C6orf82" ENSG00000112514 "CutA divalent cation tolerance homolog" O60888 6 33416442-33418317 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016787, HPA064369" Uncertain Approved "Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 26000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 32: Non-specific - Translation" "Plasma membrane, Focal adhesion sites" "CAB016787: , HPA064369: AB_2685248" "unprognostic (7.03e-2)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (8.91e-2)" "unprognostic (1.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.98e-2)" "prognostic favorable (8.50e-4)" "unprognostic (1.87e-1)" "unprognostic (2.78e-2)" "unprognostic (1.27e-3)" "unprognostic (1.91e-1)" "unprognostic (5.55e-2)" "unprognostic (9.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.94e-2)" "unprognostic (2.74e-1)" 129.0 268.0 155.3 60.3 165.9 93.9 132.4 166.2 177.1 159.6 196.0 156.7 104.5 158.7 184.8 106.4 144.4 95.1 151.1 159.6 169.9 200.3 217.8 118.3 99.0 166.1 158.3 193.8 186.3 177.2 346.6 81.5 169.6 153.8 71.2 60.3 179.2 113.0 142.8 149.5 129.1 80.1 161.9 147.1 177.5 74.2 160.9 82.7 201.6 89.2 82.5 128.2 121.9 173.0 244.5 142.0 242.7 293.8 177.6 173.9 109.7 224.0 430.1 433.1 462.7 147.5 154.1 166.1 162.2 269.1 316.0 152.4 154.5 231.3 248.9 153.2 295.1 171.8 228.9 397.0 226.3 134.2 135.9 224.7 195.8 209.8 179.8 303.7 118.8 180.9 212.9 348.7 325.1 187.2 222.0 305.1 213.8 222.6 187.5 235.9 141.8 456.4 310.1 112.3 451.7 225.4 136.2 231.3 425.8 135.5 170.8 308.7 121.3 222.6 190.0 166.5 229.8 341.7 363.9 189.5 202.9 304.9 189.3 207.8 179.2 103.6 225.8 138.1 335.1 315.7 360.7 274.6 163.6 266.5 366.5 279.2 25.6 306.9 97.2 120.0 421.9 400.4 155.3 165.9 166.2 177.1 159.6 169.9 166.1 158.3 169.6 161.9 160.9 173.0 109.5 131.4 119.3 14.0 209.5 230.6 287.9 424.5 266.9 92.6 401.0 488.6 138.2 237.4 239.7 316.3 68.8 361.6 186.2 154.0 283.7 188.3 85.4 181.8 177.9 114.7 292.1 111.7 13.0 141.0 235.5 181.4 105.5 156.8 169.9 122.6 134.2 340.1 328.6 77.4 17.4 320.1 360.1 167.1 197.1 345.2 200.0 139.2 316.6 10.3 140.0 179.7 216.3 14.1 31.2 113.3 223.9 191.5 375.7 243.3 306.6 559.1 229.5 85.9 92.1 131.1 226.7 111.0 106.4 203.5 230.4 242.9 242.4 217.8 341.3 268.4 CX3CL1 "ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1" ENSG00000006210 "C-X3-C motif chemokine ligand 1" P78423 16 57372477-57385044 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Chemotaxis, Host-virus interaction, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 104.8" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal prostatic cells: 50.8;Basal respiratory cells: 51.8;Breast glandular cells: 62.3;Breast myoepithelial cells: 51.1;Club cells: 54.8;Endothelial cells: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "EFO-21: 30.1;HDLM-2: 86.0;Hep G2: 63.8;RPTEC TERT1: 36.5;SK-BR-3: 21.5" "Low region specificity" "Detected in all" "CAB026192, HPA040361" Approved Supported "Plasma membrane" "Secreted to blood" NA NA 1870000 370000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB026192: , HPA040361: AB_10796453" "unprognostic (6.89e-3)" "prognostic favorable (9.46e-4)" "unprognostic (1.52e-2)" "unprognostic (3.20e-2)" "unprognostic (1.73e-1)" "unprognostic (1.82e-1)" "unprognostic (7.12e-2)" "unprognostic (2.08e-3)" "unprognostic (4.49e-2)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-2)" "prognostic favorable (8.52e-7)" "unprognostic (5.19e-2)" "unprognostic (2.72e-1)" "unprognostic (1.11e-2)" "unprognostic (9.33e-2)" 68.3 4.8 36.4 5.7 39.5 0.1 104.8 11.9 44.8 17.6 19.8 14.3 5.1 13.7 8.7 14.4 18.2 21.0 43.0 46.9 26.4 41.9 14.9 98.8 8.5 25.1 24.8 8.3 13.1 7.1 11.2 3.9 23.6 42.2 5.4 4.3 70.8 45.3 15.0 27.3 12.8 10.6 21.8 1.4 14.5 5.7 30.5 5.2 29.7 19.2 6.2 33.0 17.3 31.2 0.0 0.8 8.0 6.8 0.3 0.1 2.0 0.1 0.0 0.0 0.1 3.1 0.0 0.0 30.1 0.1 4.3 0.3 0.0 0.1 0.0 86.0 0.4 0.0 0.0 63.8 0.9 0.0 0.1 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 2.8 0.1 0.0 0.1 1.1 0.2 36.5 0.2 0.2 7.1 0.0 21.5 1.9 5.1 0.1 0.2 0.1 0.3 4.7 0.2 2.1 0.1 0.0 0.0 0.1 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 36.4 39.5 11.9 44.8 46.9 26.4 25.1 24.8 23.6 21.8 30.5 31.2 115.4 3.2 4.6 3.3 1.2 4.5 50.8 51.8 31.9 9.8 62.3 51.1 8.3 21.5 54.8 3.7 4.2 0.0 0.8 0.5 0.0 35.1 0.4 12.9 3.3 50.7 1.8 0.0 28.1 1.8 0.1 9.0 0.5 27.3 1.3 0.2 6.1 11.7 0.0 5.0 20.5 0.3 20.3 0.8 4.7 0.5 4.7 0.6 0.0 16.9 0.6 0.8 0.0 13.0 3.2 4.3 0.6 27.8 0.0 29.7 0.2 11.8 28.8 2.2 13.1 2.8 15.7 0.1 0.1 10.3 2.6 0.3 0.8 0.3 1.0 32.6 CXADR CAR ENSG00000154639 "CXADR Ig-like cell adhesion molecule" P78310 21 17513043-17593579 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 323.4;Proximal enterocytes: 263.0;Suprabasal keratinocytes: 343.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 93.4;Hep G2: 63.0;NTERA-2: 109.1;RT4: 104.4" "Low region specificity" "Detected in all" "HPA003342, CAB005103, HPA030411, HPA030412" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted - unknown location" NA NA 18000 "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" "CAB005103: AB_2087557, HPA003342: AB_1078588, HPA030411: AB_10599620, HPA030412: AB_10601992" "unprognostic (3.75e-1)" "unprognostic (1.03e-1)" "unprognostic (6.45e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (3.48e-3)" "unprognostic (1.04e-1)" "unprognostic (9.35e-2)" "unprognostic (3.89e-3)" "unprognostic (2.20e-1)" "unprognostic (8.27e-2)" "unprognostic (5.71e-3)" 3.6 2.9 7.0 2.8 8.7 2.6 9.8 6.6 10.8 7.7 22.8 22.5 42.3 5.3 15.2 14.5 10.6 18.3 9.3 8.9 7.1 8.3 49.3 13.6 0.7 10.4 6.8 0.4 15.8 6.8 4.7 0.3 9.3 15.1 25.6 4.9 15.4 14.2 0.4 53.4 42.6 3.3 9.7 2.4 30.9 12.5 7.3 1.5 22.1 0.0 4.1 25.6 10.9 17.7 16.8 9.0 44.6 0.1 0.0 0.0 26.7 0.2 0.2 0.7 2.7 93.4 14.6 6.2 19.7 0.0 13.3 28.1 22.8 6.2 1.0 9.3 19.0 0.1 24.1 63.0 2.9 1.8 0.1 0.0 24.6 1.3 0.4 10.8 9.0 5.5 0.3 0.4 0.0 1.1 3.7 0.1 109.1 15.2 0.0 0.1 15.2 12.5 38.7 104.4 18.5 12.3 10.9 12.6 6.7 45.8 25.4 0.3 0.5 0.2 25.8 0.4 6.6 4.5 7.7 0.4 3.6 0.1 0.6 1.0 0.1 0.1 0.1 0.0 0.2 0.0 0.6 0.1 0.0 0.1 0.6 0.2 0.3 0.2 0.0 0.0 0.1 0.2 7.0 8.7 6.6 10.8 8.9 7.1 10.4 6.8 9.3 9.7 7.3 17.7 0.2 141.1 79.0 2.6 1.0 323.4 172.7 110.6 132.6 16.9 58.6 28.2 29.8 161.5 106.6 103.0 27.1 0.8 0.3 238.4 5.9 130.0 5.3 118.9 8.3 4.8 80.8 9.9 60.4 93.7 0.2 8.6 94.3 128.9 5.7 1.1 47.8 127.7 0.6 0.0 43.0 107.5 81.4 22.9 13.1 7.7 2.1 3.3 23.2 40.3 0.7 13.4 0.0 78.9 161.4 93.4 155.3 0.0 1.6 125.1 263.0 4.0 85.6 11.2 6.6 0.2 5.3 6.4 24.5 117.0 343.8 0.7 4.3 0.5 107.0 202.7 CXCL1 "FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1" ENSG00000163739 "C-X-C motif chemokine ligand 1" P09341 4 73869393-73871308 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Inflammatory response" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 102.2;lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 16674.3;Club cells: 7384.0;Ionocytes: 4146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 243 "neutrophil: 47.3" "Lineage enriched" "Detected in single" 243 "granulocytes: 47.3" "Group enriched" "Detected in many" 6 "BJ hTERT+: 748.4;EFO-21: 1906.7;RPTEC TERT1: 682.0" "Secreted to blood" NA NA 384000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "prognostic favorable (7.83e-4)" "prognostic unfavorable (7.23e-4)" "unprognostic (5.24e-3)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (5.45e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.17e-1)" "unprognostic (5.30e-2)" "unprognostic (7.41e-2)" "unprognostic (9.41e-2)" 38.0 6.2 4.3 49.0 4.9 41.6 3.8 3.6 8.1 102.2 4.8 14.6 10.6 2.3 0.1 38.7 14.9 25.7 28.3 3.5 3.7 18.7 10.2 45.2 2.4 4.0 3.7 2.4 25.7 0.4 2.0 5.1 4.3 18.7 16.0 0.4 23.7 9.5 1.7 2.2 26.9 3.0 4.1 196.6 9.1 0.2 5.4 2.9 1.9 1.9 23.6 75.5 25.5 4.2 3.7 4.4 0.0 0.0 4.4 11.7 0.0 20.6 748.4 17.7 18.8 0.2 13.4 0.0 1906.7 1.3 72.5 38.6 0.0 3.5 94.2 2.8 0.0 0.0 1.3 0.0 4.4 0.0 0.0 9.7 1.3 133.2 10.6 1.4 144.7 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.4 7.7 5.4 0.0 0.0 0.0 682.0 16.7 0.1 0.0 1.5 0.3 40.4 2.0 0.5 1.9 173.9 0.0 6.6 37.8 1.5 0.0 1.6 3.7 1.9 0.1 26.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 0.0 0.0 0.0 0.0 0.0 4.3 4.9 3.6 8.1 3.5 3.7 4.0 3.7 4.3 4.1 5.4 4.2 7.9 44.8 273.3 0.0 2.9 126.6 991.1 16674.3 131.5 0.0 61.3 42.9 4.1 413.2 7384.0 5.5 0.0 0.3 1.4 40.3 0.0 1073.2 0.0 152.2 21.5 106.7 635.7 0.0 0.0 42.5 0.7 449.0 20.9 199.0 15.8 1.4 3.9 2.1 26.7 0.0 0.0 31.1 4146.2 10.4 467.3 0.0 0.0 110.8 124.5 0.0 56.9 0.0 0.0 0.0 0.0 232.8 7.6 0.0 0.1 2062.0 19.6 3.1 1219.7 0.0 0.0 152.9 217.7 0.4 0.2 48.7 105.1 0.4 27.8 0.1 66.0 1251.3 CXCL10 "C7, crg-2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10" ENSG00000169245 "C-X-C motif chemokine ligand 10" P02778 4 76021118-76023497 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 95.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 52.7;Glandular and luminal cells: 23.5;Kupffer cells: 41.1;Langerhans cells: 21.4;Macrophages: 45.7;Plasma cells: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 21.5;intermediate monocyte: 52.4;non-classical monocyte: 36.9" "Lineage enriched" "Detected in many" 15 "monocytes: 52.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 6.1;BJ hTERT+ SV40 Large T+: 2.2;BJ hTERT+ SV40 Large T+ RasG12V: 2.2;GAMG: 5.1;RPMI-8226: 4.3;RT4: 2.4;THP-1: 3.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 253000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.94e-1)" "unprognostic (5.32e-2)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-1)" "unprognostic (7.59e-2)" "prognostic favorable (1.12e-5)" "prognostic unfavorable (4.61e-4)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (1.03e-1)" "unprognostic (4.95e-2)" "unprognostic (1.73e-2)" "unprognostic (1.66e-2)" 4.0 5.9 1.4 95.5 1.5 1.2 20.7 0.9 2.6 13.2 1.2 10.7 11.2 7.1 0.7 8.0 4.1 10.6 4.4 1.2 1.0 7.8 29.0 35.1 68.0 7.4 1.2 3.0 0.9 17.1 2.1 10.3 10.8 43.9 15.9 0.4 20.1 1.8 1.2 2.0 11.2 15.8 3.4 20.3 19.2 3.0 2.6 35.2 3.7 1.1 17.3 45.1 3.7 1.5 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 6.1 2.2 2.2 0.2 0.1 2.0 0.2 0.0 5.1 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 4.3 0.1 2.4 0.0 0.0 0.0 0.4 1.3 0.0 0.1 3.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.6 0.0 0.0 21.5 0.0 0.0 52.4 0.0 1.4 0.3 0.0 3.5 0.1 0.0 0.0 1.1 0.0 36.9 0.0 0.0 7.6 1.4 1.5 0.9 2.6 1.2 1.0 7.4 1.2 10.8 3.4 2.6 1.5 3.8 0.0 2.2 0.0 2.2 0.9 9.4 52.7 0.6 0.0 2.6 7.0 0.3 1.5 2.8 0.0 0.0 0.1 0.0 2.7 0.0 5.9 2.6 12.5 10.9 8.0 0.0 0.0 0.0 0.0 0.0 6.9 3.1 23.5 1.3 0.0 0.0 0.1 17.3 0.0 0.0 1.0 10.2 41.1 21.4 4.0 0.3 45.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 11.4 6.4 2.6 1.3 0.0 0.0 1.3 12.4 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.9 1.4 CXCL11 "b-R1, H174, I-TAC, IP-9, SCYB11, SCYB9B" ENSG00000169248 "C-X-C motif chemokine ligand 11" O14625 4 76033682-76041415 "Human disease related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Basal prostatic cells: 2.6;Basal respiratory cells: 2.9;Distal enterocytes: 2.7;Exocrine glandular cells: 3.6;Macrophages: 4.3;Prostatic glandular cells: 3.7;Proximal enterocytes: 2.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 3.4;BJ hTERT+ SV40 Large T+: 5.1;BJ hTERT+ SV40 Large T+ RasG12V: 5.3;GAMG: 1.4" "Region enhanced" "Detected in single" "spinal cord: 1.2" CAB009921 Uncertain "Secreted to blood" NA NA 187000 "Cluster 3: T-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB009921: AB_2088137" "unprognostic (2.00e-1)" "unprognostic (3.62e-1)" "unprognostic (6.94e-3)" "unprognostic (1.87e-2)" "unprognostic (9.95e-2)" "unprognostic (5.85e-2)" "unprognostic (1.89e-1)" "unprognostic (1.04e-1)" "unprognostic (1.73e-1)" "prognostic favorable (4.31e-7)" "prognostic unfavorable (8.18e-5)" "unprognostic (2.90e-1)" "prognostic unfavorable (3.29e-6)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (4.48e-2)" "unprognostic (5.32e-2)" 1.6 0.4 1.5 11.1 1.3 0.3 3.7 1.1 3.5 2.5 1.0 1.7 0.8 1.5 0.2 1.0 1.6 1.2 1.2 1.2 1.2 1.3 2.4 6.0 11.9 2.3 1.4 0.5 8.9 0.1 0.3 3.6 2.2 5.2 4.3 0.0 3.1 0.3 0.3 0.3 1.2 1.7 1.6 5.8 6.3 0.9 2.0 6.3 1.2 0.0 1.4 4.6 0.6 1.3 0.8 0.2 0.0 0.0 0.0 0.1 0.0 0.0 3.4 5.1 5.3 0.0 0.1 0.6 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 1.1 3.5 1.2 1.2 2.3 1.4 2.2 1.6 2.0 1.3 0.5 3.2 0.0 0.0 0.2 0.1 2.6 2.9 0.0 0.0 0.2 0.3 0.2 1.5 0.2 0.0 0.0 0.0 0.0 2.7 0.0 2.0 0.0 0.7 0.9 2.2 0.0 0.0 0.0 3.6 0.0 0.5 0.0 1.6 0.0 0.0 0.4 0.2 1.8 0.0 0.0 0.1 0.0 2.1 0.3 0.0 0.0 4.3 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.7 2.8 0.0 0.8 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.2 0.0 1.2 1.4 CXCL12 "PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1" ENSG00000107562 "C-X-C motif chemokine ligand 12" P48061 10 44370165-44386493 "Predicted secreted proteins" "Chemotaxis, Host-virus interaction" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 347.2;Distal tubular cells: 172.1;Fibroblasts: 566.4;Kupffer cells: 191.8;Smooth muscle cells: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 509.6;BJ hTERT+: 303.5;BJ hTERT+ SV40 Large T+: 294.9;BJ hTERT+ SV40 Large T+ RasG12V: 441.2;fHDF/TERT166: 501.8;HSkMC: 1293.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017564 Approved "Secreted to blood" NA NA 1030000 560000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017564: AB_2088170" "unprognostic (2.41e-1)" "unprognostic (2.95e-2)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-2)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-3)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" 366.8 82.6 19.4 143.8 20.2 35.1 237.4 19.1 28.1 268.4 24.5 124.3 53.6 360.7 54.3 138.5 122.1 263.3 190.3 19.4 18.6 124.8 252.8 71.0 215.8 22.3 21.1 112.3 131.2 126.7 21.3 8.5 19.1 47.8 115.5 2.1 116.3 66.2 158.9 99.4 96.5 343.5 19.9 356.6 45.4 19.4 21.0 142.6 103.4 181.3 119.7 107.0 174.3 17.7 0.0 0.0 0.4 0.6 509.6 78.9 0.4 187.7 303.5 294.9 441.2 0.0 0.1 0.2 1.9 501.8 0.0 0.1 0.8 0.2 97.1 187.2 2.4 0.0 0.0 0.0 172.8 0.4 0.9 1293.8 0.0 63.8 0.1 0.0 0.2 0.1 0.1 0.0 1.0 0.4 0.7 0.6 32.2 0.0 0.6 0.8 0.3 224.3 0.2 0.0 0.6 0.6 0.3 0.7 0.0 63.6 272.2 0.4 0.4 0.4 0.5 205.0 0.2 0.2 0.1 0.1 0.6 0.3 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 20.2 19.1 28.1 19.4 18.6 22.3 21.1 19.1 19.9 21.0 17.7 347.2 0.0 1.1 1.3 1.4 76.3 0.3 0.0 9.6 1.5 8.1 14.0 25.0 10.0 0.6 5.5 0.0 0.3 2.1 0.0 172.1 0.8 2.2 1.7 46.8 134.1 0.0 0.0 0.6 20.5 0.3 566.4 1.5 1.0 0.0 0.4 55.6 2.5 2.6 0.0 6.6 3.9 0.0 191.8 110.1 3.7 70.2 27.9 135.2 74.0 0.0 1.9 0.0 12.1 0.1 3.0 0.0 8.6 1.0 1.0 0.1 25.5 0.0 0.8 85.5 43.7 146.1 1.8 5.9 6.3 62.7 0.7 9.6 33.2 0.5 0.5 CXCL13 "ANGIE, ANGIE2, BCA-1, BLC, BLR1L, SCYB13" ENSG00000156234 "C-X-C motif chemokine ligand 13" O43927 4 77511753-77611834 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 523.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 242.2;Breast myoepithelial cells: 72.4;Endometrial stromal cells: 101.0;monocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA052613 Uncertain "Secreted to blood" NA NA 93700 "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" "HPA052613: AB_2681885" "unprognostic (5.25e-3)" "unprognostic (1.19e-2)" "prognostic favorable (9.12e-4)" "prognostic favorable (5.52e-4)" "unprognostic (1.53e-2)" "unprognostic (1.17e-3)" "unprognostic (1.49e-1)" "unprognostic (6.41e-3)" "unprognostic (9.82e-3)" "prognostic favorable (5.41e-4)" "unprognostic (1.13e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (1.16e-10)" "unprognostic (2.04e-2)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (6.68e-3)" 2.6 0.4 0.1 127.7 0.4 0.1 15.4 0.4 0.3 1.4 0.1 13.3 1.9 3.6 1.6 2.4 0.8 5.8 1.2 0.1 0.1 0.6 28.5 2.9 523.1 1.1 0.1 0.7 0.3 0.2 3.1 0.6 0.1 27.3 16.5 0.2 8.5 1.4 0.0 0.6 68.5 1.2 0.4 338.6 34.9 1.5 0.1 16.2 2.4 0.0 441.3 30.6 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.3 0.1 0.1 1.1 0.1 0.1 0.4 0.1 0.2 0.9 0.0 0.5 1.3 0.3 0.1 15.8 3.9 0.0 0.0 242.2 72.4 0.0 1.5 0.7 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 2.6 101.0 1.7 0.0 10.7 1.9 0.2 0.3 6.3 0.5 1.8 1.3 0.0 3.6 21.3 10.2 0.0 3.9 0.0 0.0 3.4 0.0 0.0 0.0 0.9 0.0 1.9 38.8 0.0 0.0 1.0 0.4 0.1 0.0 0.0 0.2 3.8 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.3 7.8 0.0 0.1 4.5 CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 780.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3435.4;Basal squamous epithelial cells: 3284.9;Breast myoepithelial cells: 1544.3;Fibroblasts: 2220.8;Glandular and luminal cells: 1201.1;Proximal tubular cells: 3662.8;Suprabasal keratinocytes: 2115.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HAP1: 61.6;hTCEpi: 79.9;RPTEC TERT1: 222.2;SuSa: 115.2;U-2 OS: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" NA NA 800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 33: Fibroblasts - ECM organization" "CAB029996: AB_2086070" "unprognostic (1.82e-3)" "prognostic favorable (1.71e-4)" "prognostic favorable (4.52e-4)" "unprognostic (2.75e-2)" "unprognostic (2.71e-3)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (9.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" 366.1 5.2 77.6 76.2 84.5 0.6 229.1 70.6 102.7 166.3 74.8 152.4 214.0 6.9 66.6 92.9 32.9 19.8 14.0 83.7 73.8 345.6 58.5 7.4 90.7 72.4 91.0 5.5 11.6 1.9 122.0 170.7 72.4 10.1 181.3 17.5 293.5 17.6 81.1 780.3 247.0 6.3 68.7 87.5 107.3 3.7 90.2 26.6 55.2 36.5 128.5 76.6 96.3 77.9 0.0 0.0 2.7 0.0 0.2 0.2 0.7 2.9 0.8 0.2 0.0 0.0 9.1 0.0 2.7 0.1 3.8 0.2 61.6 1.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 79.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 4.0 0.0 0.0 0.2 0.0 1.1 222.2 0.0 1.1 0.7 0.2 0.2 0.0 115.2 0.1 0.0 0.0 0.1 84.9 0.4 0.1 0.3 0.0 0.0 1.4 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 77.6 84.5 70.6 102.7 83.7 73.8 72.4 91.0 72.4 68.7 90.2 77.9 123.8 0.0 1.1 32.7 13.1 3435.4 14.4 276.9 3284.9 245.7 47.5 1544.3 4.1 0.0 5.1 283.3 0.0 35.9 6.1 0.0 563.4 0.0 0.8 45.0 140.8 45.9 0.0 0.0 1.0 0.0 25.4 2220.8 0.5 1201.1 0.0 0.0 43.5 0.2 63.6 6.7 150.8 0.0 240.1 0.9 887.9 1.3 20.8 35.3 439.4 8.4 0.0 6.7 0.0 4.5 4.2 0.1 0.0 0.4 13.3 10.6 0.0 3662.8 2.1 19.0 0.0 889.8 99.2 0.4 5.2 69.3 2115.0 77.2 43.4 0.3 0.1 9.3 CXCL17 "Dcip1, DMC, UNQ473, VCC1" ENSG00000189377 "C-X-C motif chemokine ligand 17" Q6UXB2 19 42428278-42442946 "Predicted secreted proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 120.5;lung: 149.0;salivary gland: 145.6;stomach 1: 358.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 513.8;Basal respiratory cells: 988.1;Club cells: 1743.3;Respiratory ciliated cells: 383.0;Urothelial cells: 1584.1" "Cancer enhanced" "Detected in many" "cervical cancer: 170.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "OE19: 8.7;RT4: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.74e-1)" "unprognostic (3.96e-2)" "unprognostic (2.78e-1)" "unprognostic (1.03e-2)" "unprognostic (4.46e-3)" "unprognostic (3.77e-1)" "prognostic favorable (4.92e-5)" "unprognostic (6.68e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.70e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-1)" "unprognostic (1.88e-1)" "unprognostic (8.13e-3)" "unprognostic (2.29e-1)" 0.2 0.1 0.1 0.1 0.0 0.0 2.3 0.2 0.1 19.2 0.0 0.8 0.7 0.9 22.3 120.5 27.1 6.5 0.1 0.1 0.0 0.2 0.1 149.0 0.0 0.0 0.0 0.3 42.9 0.0 0.6 0.0 0.0 8.2 0.0 0.0 145.6 0.4 0.0 0.3 0.0 0.1 0.0 0.2 358.6 0.1 0.0 1.1 0.5 0.0 24.2 47.6 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 8.7 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 35.3 513.8 0.3 0.1 0.0 225.5 988.1 1.2 0.4 21.5 10.3 0.0 4.3 1743.3 5.5 0.0 0.0 0.2 0.2 0.0 8.7 0.4 3.0 0.6 3.5 0.0 0.0 1.5 187.4 0.0 4.3 302.2 8.4 16.4 0.1 0.0 0.0 0.0 0.0 1.2 0.0 227.9 0.0 0.0 1.5 0.0 3.9 0.0 0.0 2.6 0.2 0.0 0.5 0.5 339.6 0.0 0.0 0.5 221.2 0.0 0.2 383.0 0.6 0.0 0.0 67.6 0.1 0.6 91.6 0.0 0.0 2.4 0.0 0.2 1584.1 CXCL2 "CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, SCYB2" ENSG00000081041 "C-X-C motif chemokine ligand 2" P19875 4 74097040-74099196 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 509.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1668.3;Basal respiratory cells: 3166.0;Basal squamous epithelial cells: 1671.5;Langerhans cells: 2390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 1.1;non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 10 "monocytes: 1.1" "Cell line enriched" "Detected in many" 8 "GAMG: 430.9" "Secreted to blood" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "prognostic favorable (5.93e-5)" "prognostic unfavorable (1.41e-4)" "unprognostic (5.28e-3)" "unprognostic (1.36e-1)" "unprognostic (2.64e-3)" "unprognostic (1.27e-1)" "unprognostic (7.14e-3)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "unprognostic (1.49e-1)" "unprognostic (6.72e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.07e-6)" "unprognostic (1.05e-2)" "unprognostic (2.33e-1)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" 95.6 12.5 4.7 28.2 3.7 88.7 39.6 3.3 6.1 61.0 4.0 9.6 3.5 15.1 0.3 12.2 17.4 52.2 49.8 4.3 10.1 14.7 509.9 87.6 12.6 5.8 4.7 9.1 88.3 2.7 7.2 3.8 4.0 13.4 21.1 1.7 20.7 10.0 21.5 3.2 11.0 14.8 4.4 7.8 26.6 1.3 9.7 3.8 6.6 35.6 1.3 82.1 3.4 4.2 1.3 3.8 0.2 0.0 1.3 4.4 0.1 4.2 52.9 2.1 6.2 0.3 8.0 0.0 7.0 0.3 430.9 0.1 0.3 11.2 8.4 0.1 0.2 3.3 5.0 0.0 35.6 1.4 0.0 4.0 38.5 27.2 37.0 1.4 4.6 0.1 0.1 0.0 1.1 0.0 0.5 0.5 0.0 4.6 1.1 0.0 0.0 0.0 26.2 0.0 0.0 0.1 2.5 0.4 1.1 0.4 0.1 0.1 7.1 1.9 0.7 7.7 4.0 0.1 0.1 0.1 30.8 8.9 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 4.7 3.7 3.3 6.1 4.3 10.1 5.8 4.7 4.0 4.4 9.7 4.2 620.7 477.5 1668.3 1.0 15.0 415.5 336.3 3166.0 1671.5 0.0 762.9 283.3 22.9 469.0 957.6 9.2 0.0 3.3 17.9 91.4 0.0 858.1 1.1 489.8 149.1 677.8 132.1 34.7 0.0 603.6 3.1 488.7 206.9 1223.1 85.2 0.1 365.1 325.8 117.3 0.0 0.0 131.6 498.5 291.4 2390.3 0.8 15.8 926.0 277.5 0.0 50.7 0.6 0.0 0.0 0.0 282.5 14.6 0.0 35.3 342.6 57.8 1.1 194.1 0.3 72.3 131.8 288.7 1.1 5.0 440.3 227.7 2.2 36.3 0.6 128.5 119.1 CXCL3 "CINC-2b, GRO3, GROg, MIP-2b, SCYB3" ENSG00000163734 "C-X-C motif chemokine ligand 3" P19876 4 74036589-74038807 "Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 20.8;cervix: 20.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2244.7;Club cells: 738.5;Ionocytes: 724.2;Langerhans cells: 2366.2;Macrophages: 718.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.4;stomach cancer: 18.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 48.5;hTEC/SVTERT24-B: 75.0;RPTEC TERT1: 43.8" "Secreted to blood" NA NA 28700 "Cluster 82: Adipose tissue - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.12e-3)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.08e-3)" "unprognostic (6.97e-3)" "unprognostic (2.41e-2)" "unprognostic (2.74e-1)" "unprognostic (5.80e-4)" "unprognostic (2.45e-2)" "unprognostic (2.24e-1)" "unprognostic (2.68e-1)" "unprognostic (9.69e-2)" "unprognostic (1.81e-1)" "unprognostic (2.89e-6)" "unprognostic (2.61e-3)" "unprognostic (1.31e-1)" "unprognostic (1.13e-2)" "unprognostic (1.20e-1)" 20.8 1.0 0.7 14.4 0.4 15.8 1.6 0.4 2.2 20.7 0.6 4.1 0.7 0.7 0.0 1.0 1.3 6.9 6.4 0.5 0.6 1.4 3.9 15.8 0.7 0.6 0.6 1.0 1.8 0.1 0.5 0.6 0.5 1.7 9.2 0.1 5.9 0.3 0.5 0.5 2.5 1.6 0.5 2.0 8.9 0.3 2.7 2.0 0.7 1.0 0.7 15.9 0.6 0.7 0.5 3.7 1.5 0.0 0.8 1.4 0.0 5.3 48.5 1.3 2.9 0.1 5.9 0.0 5.2 0.0 17.6 0.2 0.3 1.7 10.5 0.0 0.0 4.1 0.6 0.0 5.7 0.5 0.0 1.1 1.2 75.0 7.3 1.2 1.1 0.8 0.9 0.0 2.1 0.0 1.1 0.2 0.7 7.0 1.5 0.1 1.7 0.0 43.8 1.3 0.0 0.0 0.5 0.0 1.1 0.7 0.2 0.0 2.0 10.5 0.6 5.3 13.7 0.0 0.0 0.0 11.9 0.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.7 0.4 0.4 2.2 0.5 0.6 0.6 0.6 0.5 0.5 2.7 0.7 34.2 99.3 244.9 1.6 10.1 228.4 205.6 2244.7 340.9 0.0 123.0 79.9 14.8 125.8 738.5 5.5 0.0 0.7 5.9 137.1 0.0 217.6 1.7 103.4 24.3 113.7 52.9 0.0 0.0 96.7 1.1 161.0 408.7 157.2 27.3 0.2 15.7 1.4 72.2 0.0 0.0 168.3 724.2 162.9 2366.2 5.6 14.0 718.0 188.5 1.0 28.1 0.0 0.0 0.0 0.0 186.1 33.5 0.4 5.1 225.9 95.7 0.2 144.2 0.0 39.5 78.5 92.6 1.7 8.3 50.3 148.6 8.1 14.0 0.1 197.5 79.7 CXCL5 "ENA-78, SCYB5" ENSG00000163735 "C-X-C motif chemokine ligand 5" P42830 4 73995642-73998677 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 35.9;salivary gland: 50.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 64.6;Ductal cells: 94.0;Macrophages: 222.6;Pancreatic endocrine cells: 245.4" "Group enriched" "Detected in many" 4 "pancreatic cancer: 56.2;stomach cancer: 74.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 191.9;EFO-21: 157.0;HSkMC: 111.4;hTEC/SVTERT24-B: 81.6;RPTEC TERT1: 603.6" HPA065474 Approved Approved Vesicles "Secreted to blood" NA NA 1110000 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA065474: AB_2685494" "unprognostic (5.56e-3)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.80e-2)" "unprognostic (1.43e-2)" "unprognostic (2.04e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.06e-2)" "unprognostic (3.04e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (7.99e-2)" "prognostic unfavorable (2.45e-5)" "unprognostic (3.72e-1)" "unprognostic (3.07e-1)" "unprognostic (2.72e-2)" "unprognostic (9.30e-2)" 2.1 0.2 1.5 35.9 0.9 1.2 3.2 0.6 8.8 7.7 0.4 0.7 0.8 0.2 0.0 0.1 0.2 4.8 0.6 0.8 2.6 0.2 1.3 10.0 6.3 1.4 2.1 0.0 0.5 0.0 0.1 0.2 3.1 1.3 0.3 0.0 50.2 0.5 0.1 0.0 2.1 0.2 1.1 2.1 8.5 0.4 5.7 0.6 0.0 0.2 0.6 8.4 0.0 0.7 0.1 191.9 0.7 0.0 0.3 6.9 0.0 3.5 2.9 1.5 3.0 0.6 1.6 0.0 157.0 0.1 34.0 0.4 0.0 0.0 17.6 0.2 0.0 0.0 0.0 0.0 15.1 0.0 0.0 111.4 0.0 81.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 603.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.5 0.0 1.0 0.0 0.1 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.0 1.5 0.9 0.6 8.8 0.8 2.6 1.4 2.1 3.1 1.1 5.7 0.7 0.2 3.2 0.0 0.0 0.0 0.9 0.7 64.6 0.0 0.0 8.0 4.4 1.2 15.7 33.2 0.0 0.0 0.0 0.1 1.3 0.0 94.0 0.7 0.7 0.1 1.8 0.0 0.0 0.3 1.4 0.1 3.6 15.3 1.2 0.0 0.0 0.7 0.0 0.5 0.0 0.3 0.7 4.1 0.3 30.4 0.3 0.0 222.6 0.0 1.0 2.1 0.0 0.0 0.0 0.1 245.4 0.0 0.0 0.3 3.1 0.0 0.1 4.3 0.0 0.0 0.6 4.0 0.1 0.6 0.0 0.3 0.0 0.3 0.0 1.1 2.0 CXCL6 "CKA-3, GCP-2, SCYB6" ENSG00000124875 "C-X-C motif chemokine ligand 6" P80162 4 73836640-73849064 "Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 36.0;lymphoid tissue: 100.8;urinary bladder: 26.5" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 241.2;Basal respiratory cells: 509.4;Cholangiocytes: 317.4;Club cells: 361.3;Ductal cells: 1120.6;Prostatic glandular cells: 245.5;Urothelial cells: 328.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "cerebral cortex: 5.3" "Immune cell enriched" "Detected in single" 104 "neutrophil: 10.4" "Lineage enriched" "Detected in single" 104 "granulocytes: 10.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 53.2;EFO-21: 136.5;hTEC/SVTERT24-B: 28.8;HUVEC TERT2: 84.5;RPTEC TERT1: 98.4" "Region enhanced" "Detected in many" "basal ganglia: 9.6" "Not detected" "Not detected" "Secreted to blood" NA NA 108000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (4.35e-4)" "unprognostic (4.47e-2)" "unprognostic (6.09e-2)" "unprognostic (4.60e-2)" "unprognostic (1.98e-2)" "unprognostic (1.17e-1)" "unprognostic (3.49e-3)" "unprognostic (2.62e-1)" "unprognostic (2.05e-1)" "unprognostic (2.02e-2)" "unprognostic (3.75e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.47e-1)" "unprognostic (4.88e-1)" "unprognostic (2.72e-1)" "unprognostic (4.48e-2)" 6.0 0.1 0.5 14.1 0.8 2.1 0.6 0.2 5.3 4.6 2.7 0.9 8.0 0.0 0.1 2.5 2.4 36.0 3.2 0.3 0.6 3.7 6.6 2.7 0.3 0.4 0.4 0.1 5.3 0.0 0.2 0.1 0.6 3.5 0.6 0.0 3.8 10.8 0.0 0.0 10.3 0.3 0.2 100.8 1.2 0.3 0.9 2.6 0.0 0.3 2.8 26.5 5.6 0.3 0.0 0.0 0.5 0.0 4.4 16.6 0.0 3.3 53.2 0.4 0.7 0.0 0.0 0.0 136.5 0.2 5.3 11.8 0.0 0.0 8.1 1.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 10.1 0.3 28.8 0.0 0.4 84.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.9 0.0 3.9 0.0 0.0 0.0 98.4 1.9 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.0 1.4 0.9 0.5 0.0 0.6 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.2 5.3 0.3 0.6 0.4 0.4 0.6 0.2 0.9 0.3 0.0 3.2 2.0 0.0 0.1 0.4 241.2 509.4 0.0 0.0 2.9 1.3 0.2 317.4 361.3 0.0 0.0 0.0 0.0 0.2 0.0 1120.6 0.0 0.7 0.1 2.0 78.1 0.0 0.0 3.9 0.0 13.2 0.0 1.3 0.0 0.3 0.0 0.6 0.2 0.0 0.0 0.2 97.6 0.3 0.8 0.1 0.0 1.1 0.0 0.0 7.8 0.0 0.0 0.0 0.0 43.5 0.0 0.0 0.0 245.5 0.0 0.3 75.7 0.0 0.0 1.5 18.4 0.0 1.2 0.3 0.1 0.0 0.1 0.0 0.1 328.4 CXCL8 "3-10C, AMCF-I, b-ENAP, GCP-1, GCP1, IL-8, IL8, K60, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8, TSG-1" ENSG00000169429 "C-X-C motif chemokine ligand 8" P10145 4 73740541-73743716 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 3301.3" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13262.1;Macrophages: 3685.4;Prostatic glandular cells: 8869.1;Urothelial cells: 13149.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 9 "cerebral cortex: 136.1" "Immune cell enriched" "Detected in some" 451 "neutrophil: 483.0" "Lineage enriched" "Detected in single" 788 "granulocytes: 483.0" "Group enriched" "Detected in many" 5 "BJ hTERT+: 4072.6;GAMG: 1080.2" "Not detected" "Not detected" HPA057179 Supported Approved "Golgi apparatus" "Secreted to blood" NA NA 7260 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA057179: AB_2683362" "unprognostic (3.42e-1)" "prognostic unfavorable (1.18e-5)" "unprognostic (3.91e-3)" "unprognostic (8.49e-2)" "unprognostic (3.29e-2)" "unprognostic (3.03e-3)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.37e-3)" "unprognostic (3.19e-1)" "unprognostic (4.46e-1)" "unprognostic (7.19e-3)" "unprognostic (7.16e-2)" "prognostic unfavorable (3.13e-6)" "unprognostic (4.73e-2)" "unprognostic (8.57e-2)" "unprognostic (1.64e-2)" "unprognostic (6.15e-2)" 67.9 13.5 1.8 209.9 2.8 3301.3 3.6 1.7 136.1 54.5 7.6 10.6 3.6 41.0 0.2 3.7 8.9 177.2 33.8 1.7 1.6 10.8 77.7 91.2 1.2 2.1 1.6 6.0 16.1 1.8 3.2 41.1 15.1 9.6 7.3 0.9 25.4 1.5 1.3 3.2 4.9 12.7 1.9 10.3 8.8 0.7 4.9 15.2 3.4 8.1 8.7 456.7 4.0 1.9 2.7 1.4 0.0 0.1 3.9 19.4 0.2 25.7 4072.6 35.9 117.0 0.2 13.0 0.2 547.6 1.3 1080.2 48.2 0.0 1.0 562.3 1.8 0.2 0.9 0.4 6.5 6.8 41.0 2.5 12.4 1.7 119.0 2.9 12.9 124.9 0.0 1.4 0.8 0.7 0.0 0.0 55.7 0.0 14.7 20.3 0.3 0.5 0.9 317.3 17.2 0.1 0.0 1.9 0.1 61.1 0.8 0.1 5.6 308.3 56.8 5.1 15.1 55.0 0.4 0.7 1.7 252.5 30.9 88.2 1.0 0.6 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 483.0 0.0 0.0 0.0 0.0 0.1 1.8 2.8 1.7 136.1 1.7 1.6 2.1 1.6 15.1 1.9 4.9 1.9 28.6 51.3 254.1 0.0 26.4 0.0 13262.1 0.0 164.4 0.5 40.2 15.4 23.8 127.2 426.5 0.0 0.0 4.3 17.7 14.4 0.0 1695.0 3.2 717.6 257.1 712.2 19.1 8.0 0.0 260.7 5.2 1475.1 54.0 1708.7 51.2 0.5 15.7 3.6 367.1 0.0 0.0 26.4 0.0 543.0 0.0 1.9 0.6 3685.4 0.0 0.0 1178.5 0.5 0.0 0.0 0.0 584.9 0.3 0.4 27.3 8869.1 0.9 1.0 178.6 1.1 39.5 44.3 263.0 0.3 2.5 124.9 0.0 21.3 138.8 0.0 18.5 13149.4 CXCL9 "CMK, crg-10, Humig, MIG, SCYB9" ENSG00000138755 "C-X-C motif chemokine ligand 9" Q07325 4 76001275-76007509 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 309.9" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 5.0;Hofbauer cells: 6.2;Kupffer cells: 10.3;Macrophages: 12.6;Spermatogonia: 8.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "RPMI-8226: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 902000 "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "prognostic favorable (6.36e-4)" "unprognostic (6.86e-3)" "unprognostic (1.25e-2)" "prognostic favorable (2.07e-4)" "unprognostic (2.97e-1)" "unprognostic (3.78e-3)" "unprognostic (8.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.46e-2)" "prognostic favorable (8.06e-4)" "unprognostic (2.18e-3)" "unprognostic (1.88e-1)" "prognostic unfavorable (5.15e-6)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (1.57e-2)" "unprognostic (6.54e-2)" 5.5 2.0 0.1 65.1 0.2 0.2 17.5 0.1 0.6 4.9 0.3 10.2 3.0 4.8 0.7 5.3 2.8 8.5 5.9 0.1 0.1 8.7 19.1 31.8 309.9 1.8 0.2 3.8 1.4 1.5 1.0 1.7 1.6 3.7 25.3 0.0 19.0 0.7 1.5 2.9 6.0 3.2 0.3 31.2 17.5 6.0 0.2 32.8 7.1 2.5 30.6 11.1 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.1 0.1 1.8 0.2 1.6 0.3 0.2 0.3 3.4 0.0 1.7 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.7 0.0 0.0 1.8 0.0 0.0 0.2 0.4 0.0 0.2 1.3 0.1 1.1 2.1 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 5.0 1.8 6.2 0.0 0.0 0.0 0.0 10.3 3.6 1.3 0.6 12.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 3.5 1.7 8.0 0.0 0.3 0.1 0.5 0.0 0.1 0.4 CXorf38 MGC39350 ENSG00000185753 "Chromosome X open reading frame 38" Q8TB03 X 40626921-40647561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 61.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050120 Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "Vesicles, Cytosol" "HPA050120: AB_2681024" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "unprognostic (2.91e-1)" "unprognostic (6.98e-2)" "unprognostic (1.37e-1)" "unprognostic (3.15e-1)" "unprognostic (1.48e-3)" "unprognostic (7.59e-2)" "unprognostic (1.46e-1)" "unprognostic (9.40e-2)" "prognostic unfavorable (7.30e-4)" "unprognostic (1.23e-1)" "unprognostic (1.71e-3)" "unprognostic (2.87e-2)" "unprognostic (1.23e-1)" "unprognostic (4.73e-2)" "prognostic favorable (1.44e-8)" 9.0 8.2 5.1 11.5 5.9 10.5 8.2 5.8 5.3 8.0 4.5 7.6 8.3 7.3 4.6 6.1 10.0 6.4 4.8 4.9 5.3 8.1 8.0 10.2 16.1 6.2 5.6 9.5 6.0 9.5 4.8 6.8 6.3 6.3 7.7 5.7 6.5 6.1 5.0 7.9 9.7 5.8 5.8 14.4 6.6 2.1 5.9 13.2 11.1 4.1 13.4 7.2 7.0 7.0 11.3 5.9 6.2 4.9 6.5 10.8 3.3 7.5 10.5 9.1 9.1 7.7 15.8 18.5 6.4 11.2 15.2 7.4 7.6 12.5 8.3 25.7 11.4 12.5 7.1 4.6 10.8 22.0 18.6 9.6 9.0 12.7 12.5 8.7 10.4 15.8 5.3 13.7 17.0 10.5 15.4 16.7 5.6 8.2 12.8 12.7 13.2 14.4 10.7 17.0 7.0 9.6 15.1 7.5 8.9 11.6 11.4 10.1 13.0 11.9 6.8 8.7 6.5 14.7 5.5 7.9 15.4 11.4 8.0 9.3 16.0 22.1 9.2 15.8 9.7 6.9 8.7 7.4 14.2 9.6 7.6 7.8 19.7 7.3 25.1 5.9 10.9 10.3 5.1 5.9 5.8 5.3 4.9 5.3 6.2 5.6 6.3 5.8 5.9 7.0 19.8 9.6 9.1 10.1 26.9 3.6 11.3 6.3 10.8 12.6 10.5 8.0 6.4 18.6 7.6 16.5 18.8 9.2 48.3 15.1 7.9 27.7 1.0 25.2 15.0 14.0 7.3 6.3 11.9 30.1 9.7 8.9 9.7 21.6 17.1 16.5 10.4 10.8 36.6 15.2 13.1 12.7 8.2 30.7 9.8 1.3 9.6 29.5 3.6 8.4 61.9 10.2 41.2 12.1 17.8 40.5 17.2 5.3 16.4 14.7 15.8 14.4 7.8 7.6 6.6 13.5 9.2 6.5 7.4 9.7 5.4 8.2 31.2 20.6 13.3 28.3 CXXC5 "HSPC195, RINF, WID" ENSG00000171604 "CXXC finger protein 5" Q7LFL8 5 139647299-139683882 "Predicted intracellular proteins" Transcription "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 317.0;Early spermatids: 714.2;Horizontal cells: 541.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "MAIT T-cell: 30.0;memory B-cell: 85.1;naive B-cell: 96.7;NK-cell: 71.9;plasmacytoid DC: 59.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 210.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036508, HPA058148" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA036508: AB_10673620, HPA058148: AB_2683621" "unprognostic (3.08e-2)" "unprognostic (9.03e-2)" "prognostic favorable (2.40e-4)" "prognostic unfavorable (4.10e-7)" "unprognostic (2.91e-1)" "unprognostic (2.05e-1)" "unprognostic (1.11e-3)" "unprognostic (2.28e-2)" "unprognostic (2.12e-1)" "unprognostic (2.72e-1)" "unprognostic (2.26e-1)" "unprognostic (2.79e-2)" "unprognostic (2.63e-2)" "unprognostic (8.02e-2)" "unprognostic (1.44e-1)" "unprognostic (7.26e-2)" "unprognostic (1.57e-1)" 26.5 20.6 48.9 17.6 65.6 46.9 21.5 103.6 64.5 29.2 36.4 17.5 10.8 15.1 30.0 25.6 29.8 20.1 30.4 56.2 48.2 70.7 88.1 16.1 30.2 91.5 65.1 5.0 61.2 28.0 43.6 15.9 84.0 15.3 11.6 38.7 53.9 18.3 80.1 24.8 22.5 9.1 66.5 34.5 21.0 51.8 61.4 34.3 22.5 21.5 24.7 14.8 23.9 106.4 36.5 30.1 32.6 12.3 44.5 60.6 12.7 23.3 35.3 9.9 19.5 66.8 36.0 47.4 101.0 62.5 59.7 40.5 6.7 17.9 4.7 5.2 11.5 70.5 25.8 47.0 19.2 16.0 1.8 21.8 4.0 16.7 4.8 95.6 2.7 1.5 67.8 7.6 72.6 94.7 17.2 51.1 39.4 39.2 8.5 30.8 66.5 73.5 75.3 26.0 103.0 106.3 8.3 210.6 18.0 71.2 115.5 74.2 14.6 80.2 15.6 38.8 21.4 27.3 62.4 89.9 121.2 5.3 45.6 1.1 6.6 0.6 9.7 1.4 30.0 85.1 0.9 6.8 5.5 96.7 0.5 2.6 1.8 71.9 0.6 59.0 1.4 10.7 48.9 65.6 103.6 64.5 56.2 48.2 91.5 65.1 84.0 66.5 61.4 106.4 22.9 48.1 18.8 24.5 120.4 26.3 14.8 41.9 8.6 232.0 41.0 67.8 49.3 105.8 32.5 147.1 25.0 2.9 90.2 18.6 317.0 125.1 714.2 47.1 53.9 43.6 18.6 52.2 18.7 144.9 23.9 47.8 24.5 53.7 21.5 41.9 36.0 131.8 38.4 541.8 8.7 50.7 61.1 35.6 92.1 200.3 39.1 32.2 60.5 15.0 40.9 220.5 195.7 16.6 44.3 93.9 17.5 30.5 114.1 34.1 22.6 200.0 38.6 49.1 13.1 150.9 48.5 14.2 13.9 15.7 20.9 37.6 21.1 25.1 27.0 21.4 CYB5D2 MGC32124 ENSG00000167740 "Cytochrome b5 domain containing 2" Q8WUJ1 17 4143168-4187310 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 130.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 74.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011032, HPA042299" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum, Plasma membrane" "HPA011032: , HPA042299: AB_10793879" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (4.16e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.88e-2)" "unprognostic (1.75e-2)" "prognostic favorable (4.98e-6)" "unprognostic (1.57e-1)" "unprognostic (2.47e-1)" "unprognostic (9.71e-3)" "prognostic favorable (7.76e-5)" "unprognostic (2.04e-1)" "prognostic favorable (2.03e-10)" "unprognostic (2.01e-3)" "unprognostic (8.73e-2)" "unprognostic (1.82e-1)" "unprognostic (2.97e-1)" 19.0 21.7 17.4 6.1 17.3 4.3 18.2 17.4 20.1 15.9 14.2 10.7 15.2 15.6 28.5 10.9 18.7 16.3 14.0 16.7 19.6 25.5 29.0 9.7 9.3 18.1 17.6 20.8 19.7 30.9 24.1 10.8 17.8 13.5 7.4 9.2 20.0 17.6 16.2 14.4 12.1 8.4 17.6 9.6 16.0 29.3 17.9 10.2 22.7 14.9 7.2 12.9 11.7 18.7 16.2 21.6 11.8 12.7 74.7 22.5 5.2 15.7 31.5 11.0 10.9 6.3 10.3 5.3 13.6 17.4 9.2 22.5 4.9 7.1 4.4 17.9 25.7 5.0 13.5 10.5 13.7 2.1 9.5 28.8 17.0 6.2 11.7 22.3 20.1 11.5 5.1 31.2 8.3 20.6 7.8 3.4 4.3 13.7 11.5 9.2 10.6 12.5 25.1 8.5 9.3 8.1 17.2 9.9 23.5 13.1 25.6 3.2 28.5 15.7 4.0 14.5 8.0 5.8 4.9 3.9 19.9 4.5 6.2 0.6 10.8 13.6 5.9 9.2 6.7 8.1 9.3 7.4 10.5 7.1 8.6 8.0 9.5 5.5 8.7 11.3 11.2 8.2 17.4 17.3 17.4 20.1 16.7 19.6 18.1 17.6 17.8 17.6 17.9 18.7 57.4 12.8 10.3 9.1 17.2 53.7 18.4 36.0 12.5 26.9 35.4 36.7 9.8 45.8 21.8 31.3 58.4 55.7 11.4 18.5 52.8 34.3 28.5 36.6 20.0 34.4 13.8 33.3 7.6 27.0 29.1 23.8 19.4 23.4 11.4 22.3 41.0 32.9 21.4 40.4 10.4 16.0 36.7 24.0 23.8 30.6 28.9 17.3 14.2 4.7 15.4 37.6 15.5 8.5 10.0 26.9 18.9 28.6 17.6 8.3 39.7 55.7 38.5 30.4 0.0 15.2 20.1 130.3 29.2 9.5 42.9 38.6 15.8 39.3 16.6 15.8 CYBA p22-PHOX ENSG00000051523 "Cytochrome b-245 alpha chain" P13498 16 88643289-88651054 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" Oxidoreductase "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 742.0;lymphoid tissue: 693.1" "Cell type enhanced" "Detected in many" "dendritic cells: 1632.1;Hofbauer cells: 2171.9;Kupffer cells: 1734.2;Macrophages: 1682.8;monocytes: 1688.5;NK-cells: 1805.4;Plasma cells: 1990.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 733.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 1058.3;RPMI-8226: 1631.2;THP-1: 1231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009492 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009492: AB_2090309" "prognostic favorable (8.19e-4)" "unprognostic (1.05e-1)" "unprognostic (8.32e-2)" "prognostic favorable (4.75e-5)" "unprognostic (2.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.88e-2)" "unprognostic (9.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.91e-1)" "unprognostic (5.22e-2)" "unprognostic (2.57e-2)" "unprognostic (1.63e-2)" 149.9 68.0 40.3 344.4 41.8 742.0 93.3 46.0 58.0 81.9 62.4 200.9 196.6 60.8 38.5 80.9 95.4 122.5 93.2 38.6 55.0 187.7 71.5 234.6 333.8 73.8 49.3 40.0 108.6 13.4 40.6 54.9 64.1 75.2 79.9 1.8 116.7 26.6 41.8 39.4 245.3 51.3 65.4 693.1 236.0 10.4 62.4 87.1 136.5 19.9 192.8 144.6 74.1 92.2 2.5 663.0 2.6 1.5 1.3 0.4 329.5 155.7 77.3 39.3 24.1 447.2 819.6 510.5 420.7 56.4 0.0 250.5 21.4 0.9 5.8 146.1 564.1 99.0 217.7 694.9 75.7 156.3 397.6 80.7 0.0 1.6 0.3 1.9 23.9 103.6 278.5 567.5 3.2 1058.3 147.9 822.3 106.2 248.7 1.5 437.9 1.6 1631.2 324.9 490.9 84.2 76.5 482.7 78.8 138.5 60.8 1.4 1231.3 129.8 1.5 6.1 1.8 2.2 362.9 459.9 543.6 195.5 464.9 53.4 120.2 103.8 733.7 76.7 150.1 55.8 109.8 36.7 70.4 107.0 110.7 28.9 36.7 192.3 36.4 143.3 196.3 41.2 47.3 40.3 41.8 46.0 58.0 38.6 55.0 73.8 49.3 64.1 65.4 62.4 92.2 157.8 16.0 12.4 0.0 1290.9 119.4 233.4 420.8 53.5 0.4 131.7 133.2 12.8 368.9 487.1 285.1 2.1 45.3 1632.1 807.2 127.2 636.8 4.2 219.5 137.5 137.1 230.5 162.7 0.2 155.3 299.0 184.8 285.4 312.5 279.0 104.3 317.0 23.9 2171.9 0.0 0.2 540.3 233.9 1734.2 1370.8 14.0 50.1 1682.8 1152.6 32.8 1688.5 1.6 1805.4 1.0 0.2 682.8 1045.8 21.4 1990.6 191.8 390.4 1057.4 529.7 2.7 59.2 44.0 164.3 0.9 15.6 75.2 85.7 118.2 838.6 20.5 805.2 436.9 CYBC1 "C17orf62, Eros, FLJ90469, MGC4368" ENSG00000178927 "Cytochrome b-245 chaperone 1" Q9BQA9 17 82442586-82450829 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Chaperone "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 47.4;Ductal cells: 39.7;Granulosa cells: 56.1;Hofbauer cells: 80.2;monocytes: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045696 Uncertain Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Cell Junctions" "HPA045696: AB_2679421" "unprognostic (1.87e-2)" "unprognostic (6.92e-3)" "unprognostic (2.25e-1)" "unprognostic (2.15e-3)" "unprognostic (5.75e-2)" "unprognostic (2.05e-3)" "unprognostic (3.81e-3)" "unprognostic (4.86e-2)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (3.49e-3)" "unprognostic (7.99e-2)" "prognostic unfavorable (6.83e-11)" "unprognostic (1.47e-1)" "unprognostic (5.51e-2)" "unprognostic (7.78e-2)" "unprognostic (9.14e-3)" 39.2 35.7 34.4 70.1 36.1 37.2 37.4 36.7 42.6 40.9 36.3 33.8 24.6 33.7 23.7 34.1 34.9 46.0 30.7 33.2 35.6 51.2 64.9 41.4 110.5 41.8 37.8 33.8 45.0 24.5 25.9 30.7 37.7 43.4 27.7 9.9 30.8 23.2 14.9 29.4 49.3 40.7 37.1 117.4 36.9 17.8 36.7 63.3 28.9 13.6 72.1 49.7 28.2 40.6 48.5 67.4 37.1 61.4 57.9 60.6 35.0 42.2 51.6 61.8 73.1 26.2 47.8 122.4 37.8 60.6 75.4 48.3 25.7 32.4 42.6 87.4 21.1 33.4 19.2 30.6 59.3 38.1 94.4 68.5 45.7 53.1 29.3 59.0 81.5 90.3 28.4 88.2 52.9 50.8 160.2 33.0 27.5 65.0 35.3 120.1 22.7 93.1 44.8 60.7 31.7 60.7 77.0 88.1 55.7 66.3 91.4 148.3 27.9 46.7 46.0 79.3 45.9 157.8 58.3 93.1 61.2 61.0 42.5 223.8 136.7 182.9 96.3 181.3 74.7 114.8 88.2 93.6 125.2 115.9 73.0 71.1 300.6 104.5 169.4 130.9 101.1 161.4 34.4 36.1 36.7 42.6 33.2 35.6 41.8 37.8 37.7 37.1 36.7 40.6 35.6 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 19.0 17.1 0.0 0.0 0.0 22.0 0.0 27.6 47.4 0.0 9.8 39.7 0.0 11.9 21.9 12.9 0.0 0.0 0.0 33.6 36.1 10.9 0.0 12.4 0.0 56.1 0.0 0.0 80.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 54.8 0.0 0.0 0.0 0.0 34.9 0.0 0.0 11.1 0.0 0.0 19.6 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 27.6 19.5 23.8 0.0 0.0 CYHR1 "CHRP, KIAA0496, MGC13010" ENSG00000187954 "Cysteine and histidine rich 1" Q6ZMK1 8 144449582-144465667 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053653, HPA059543" Approved Enhanced Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA053653: AB_2682219, HPA059543: AB_2684056" "unprognostic (1.04e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.58e-2)" "unprognostic (8.28e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.90e-4)" "unprognostic (4.02e-2)" "unprognostic (2.63e-1)" "unprognostic (2.13e-1)" "unprognostic (7.08e-3)" "unprognostic (1.46e-1)" "unprognostic (5.33e-2)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-1)" "unprognostic (1.54e-2)" 33.6 57.9 61.2 9.2 60.3 11.1 37.1 58.2 76.1 50.5 57.1 46.8 15.8 41.0 22.8 34.7 43.1 16.0 58.9 61.7 59.5 43.1 48.8 26.6 15.3 63.7 59.9 44.7 60.9 28.9 67.5 10.2 58.6 70.5 8.8 11.2 40.5 27.6 45.9 41.5 30.0 12.0 60.5 35.0 42.1 69.8 59.6 13.7 44.1 22.6 8.5 48.9 40.3 61.2 23.0 27.6 18.3 22.6 30.8 20.7 22.9 15.5 15.9 14.6 18.4 12.8 30.6 10.4 32.5 23.3 18.1 34.0 14.4 22.6 5.6 25.3 23.9 23.6 33.7 22.1 42.9 6.0 12.4 35.6 29.9 18.2 22.7 32.2 16.9 29.0 34.8 27.7 14.0 51.5 28.9 16.6 12.0 34.5 57.5 27.3 7.7 29.6 22.5 19.5 26.7 16.4 33.5 27.9 36.6 13.9 37.5 23.8 20.1 18.4 21.5 20.5 15.6 14.0 9.9 8.4 26.5 20.2 15.2 2.9 11.7 7.0 9.5 8.4 15.5 12.9 11.9 7.8 12.7 14.0 22.2 12.5 5.8 5.3 9.5 27.0 5.0 9.6 61.2 60.3 58.2 76.1 61.7 59.5 63.7 59.9 58.6 60.5 59.6 61.2 32.6 35.3 26.5 52.5 18.5 30.5 46.2 31.8 43.9 75.6 68.7 69.6 19.0 45.8 28.7 58.8 25.0 29.2 33.3 43.2 43.0 28.1 12.5 37.2 37.3 28.9 33.7 23.4 45.9 28.7 20.1 36.4 32.6 32.7 5.1 42.9 37.9 45.6 25.6 90.9 39.4 44.0 36.7 26.7 23.2 44.1 50.7 23.0 26.6 18.7 31.0 120.5 22.6 31.7 37.2 23.2 42.9 39.9 26.2 48.5 47.6 35.0 41.7 59.0 39.5 37.4 35.5 45.8 32.3 36.8 38.8 16.7 24.3 82.2 47.3 35.6 CYP17A1 "CPT7, CYP17, P450C17, S17AH" ENSG00000148795 "Cytochrome P450 family 17 subfamily A member 1" P05093 10 102830531-102837472 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Steroidogenesis "Lyase, Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 84 "adrenal gland: 8229.5" "Cell type enriched" "Detected in some" 17 "Theca cells: 1871.0" "Cancer enriched" "Detected in many" 5 "liver cancer: 22.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 3.0;SCLC-21H: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA048533 Enhanced Approved Vesicles "Intracellular and membrane" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA048533: AB_2680432" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (3.01e-2)" "unprognostic (9.08e-2)" "unprognostic (1.91e-1)" "unprognostic (6.29e-2)" "unprognostic (2.92e-3)" "unprognostic (2.39e-4)" "unprognostic (8.26e-2)" "unprognostic (2.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.13e-1)" "prognostic favorable (5.43e-7)" "unprognostic (1.07e-1)" "unprognostic (5.56e-2)" "unprognostic (1.66e-2)" "unprognostic (2.94e-4)" 0.4 8229.5 0.0 2.1 0.0 0.0 0.4 0.1 0.1 1.1 0.0 0.5 0.0 0.8 0.1 0.9 1.0 0.4 1.0 0.0 0.0 52.9 6.7 1.4 0.0 0.0 0.1 16.6 1.7 10.5 0.7 0.0 0.0 0.7 0.0 0.2 3.4 0.0 1.0 0.7 0.6 0.0 0.0 0.9 1.3 98.3 0.0 0.0 2.9 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 2.2 0.1 0.4 0.1 0.0 0.5 0.0 0.1 0.7 0.0 0.0 1.8 0.0 0.4 0.1 0.1 21.5 0.0 41.6 0.1 0.0 0.7 0.0 2.7 0.1 0.2 0.0 1.3 0.0 0.1 0.0 0.1 0.4 6.1 0.1 1.7 0.1 0.0 0.0 0.6 0.7 10.6 1.8 0.9 0.0 0.0 0.1 0.2 3.1 0.5 0.1 0.7 0.0 0.0 0.0 0.3 0.0 104.3 0.0 1.2 0.0 1.2 0.6 0.3 0.1 0.0 0.0 0.3 0.4 1871.0 0.0 0.1 CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338601 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 124.4" "Cell type enriched" "Detected in some" 10 "Syncytiotrophoblasts: 2007.5" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Group enriched" "Detected in many" 4 "amygdala: 4.8;hypothalamus: 4.1;medulla oblongata: 1.4;midbrain: 2.0;thalamus: 3.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 92.8;HDLM-2: 17.5;HSkMC: 31.4;SuSa: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000355, HPA051194" Enhanced Uncertain Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "CAB000355: , HPA051194: AB_2681381" "unprognostic (9.41e-2)" "unprognostic (7.44e-2)" "unprognostic (9.52e-5)" "unprognostic (6.81e-2)" "unprognostic (2.72e-1)" "unprognostic (4.25e-4)" "unprognostic (5.18e-5)" "unprognostic (1.54e-3)" "unprognostic (2.38e-2)" "unprognostic (2.52e-1)" "unprognostic (1.97e-1)" "unprognostic (5.37e-2)" "unprognostic (1.54e-5)" "unprognostic (2.52e-3)" "unprognostic (2.11e-1)" "unprognostic (1.40e-2)" "unprognostic (1.11e-1)" 8.3 9.0 4.8 0.4 0.6 0.2 2.1 0.1 0.5 0.6 0.0 0.2 0.7 0.3 0.0 0.1 0.3 0.5 1.2 0.3 4.1 0.1 0.1 0.7 0.0 1.4 2.0 3.2 1.3 0.2 0.0 124.4 0.7 0.6 0.1 0.6 0.9 2.7 0.6 1.8 0.2 1.3 0.2 0.6 0.2 6.5 3.7 0.2 2.4 0.3 0.0 3.5 0.5 0.7 0.1 0.0 0.0 0.0 1.7 92.8 6.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.3 0.5 0.4 0.0 0.0 0.0 0.0 17.5 0.0 0.6 0.2 8.1 0.6 0.0 0.1 31.4 0.0 0.3 4.0 0.3 0.0 0.0 0.0 0.8 0.4 0.7 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.4 0.2 16.3 0.0 0.5 0.1 0.3 0.1 0.2 0.0 3.0 1.6 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.1 0.5 0.3 4.1 1.4 2.0 0.7 0.2 3.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 52.8 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.0 0.1 0.0 7.9 1.5 0.0 0.0 0.0 191.3 0.0 0.0 14.0 0.0 0.3 0.0 0.0 0.9 0.0 5.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.2 0.9 12.3 0.3 0.0 0.0 2007.5 0.0 22.2 0.0 0.0 CYP21A2 "CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B" ENSG00000231852 "Cytochrome P450 family 21 subfamily A member 2" P08686 6 32038327-32041644 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Steroidogenesis "Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 46 "adrenal gland: 2041.7" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 15.9" "Cancer enhanced" "Detected in some" "liver cancer: 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HDLM-2: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048979, HPA053371" Enhanced NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA048979: AB_2680584, HPA053371: AB_2682131" "unprognostic (1.03e-2)" "unprognostic (1.65e-1)" "unprognostic (1.02e-4)" "unprognostic (2.58e-1)" "unprognostic (2.97e-1)" "unprognostic (2.93e-2)" "unprognostic (2.76e-2)" "unprognostic (8.75e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (6.67e-7)" "unprognostic (7.39e-2)" "unprognostic (5.24e-2)" "unprognostic (1.09e-1)" "unprognostic (1.82e-1)" 2.0 2041.7 0.0 0.0 0.0 0.0 1.5 0.0 0.6 1.9 0.0 2.5 0.0 1.5 0.6 0.6 2.4 0.0 2.9 0.0 0.0 7.0 44.8 0.8 0.0 0.0 0.0 4.3 0.9 0.0 1.9 0.0 0.0 1.9 0.0 0.0 4.0 0.0 0.3 0.7 1.1 0.0 0.0 5.5 0.8 0.8 0.0 0.0 2.3 0.0 0.0 2.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.4 2.4 0.5 0.3 1.5 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.1 0.8 0.9 1.8 0.0 0.1 0.0 0.0 1.6 0.0 0.2 1.3 0.4 0.0 15.9 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.6 0.1 1.8 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 2.0 1.2 0.6 0.0 0.3 0.6 0.6 0.4 0.0 0.0 0.0 0.3 1.0 0.0 0.0 CYP26B1 P450RAI-2 ENSG00000003137 "Cytochrome P450 family 26 subfamily B member 1" Q9NR63 2 72129238-72147862 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;skin 1: 31.4" "Group enriched" "Detected in many" 4 "Leydig cells: 75.8;Peritubular cells: 229.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 9.8;HaCaT: 14.8;RH-30: 18.4;U-2 OS: 19.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012567 Uncertain Approved Cytosol "Intracellular and membrane" No No "Cluster 27: Brain & Skin - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA012567: AB_1847429" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (2.19e-4)" "unprognostic (3.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.17e-4)" "unprognostic (8.41e-2)" "unprognostic (1.51e-1)" "unprognostic (1.40e-1)" "unprognostic (7.55e-3)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.55e-1)" "unprognostic (9.44e-3)" "unprognostic (2.04e-2)" 26.2 4.3 12.0 1.9 3.3 0.1 15.0 12.3 7.0 5.0 0.4 3.2 3.7 2.5 1.5 3.9 5.5 1.1 8.5 6.7 1.3 8.8 1.0 2.7 4.9 48.0 10.4 4.5 0.6 0.8 9.3 3.3 49.9 2.6 1.2 4.2 9.9 7.3 5.9 31.4 4.7 1.6 0.0 3.5 1.2 13.8 0.7 19.3 14.4 2.3 2.9 3.2 4.2 3.5 0.6 5.9 0.0 0.1 9.8 4.0 5.9 0.9 0.1 0.2 0.2 1.8 0.5 0.0 0.5 0.7 3.0 14.8 8.5 0.0 0.1 0.0 2.7 0.0 7.0 0.9 0.2 0.0 0.3 0.0 0.5 0.0 0.3 3.0 1.1 4.0 0.6 0.1 0.9 2.9 0.0 0.1 0.0 0.1 1.0 0.1 18.4 0.0 0.0 1.3 0.6 0.1 3.0 0.0 3.5 1.2 0.3 0.9 0.0 1.6 19.3 9.0 3.0 0.1 1.2 0.0 6.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 3.3 12.3 7.0 6.7 1.3 48.0 10.4 49.9 0.0 0.7 3.5 2.4 0.0 0.0 2.0 1.2 14.7 1.1 0.8 0.6 0.2 2.3 0.8 1.4 4.3 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.2 4.1 0.2 0.2 19.0 1.8 5.3 5.3 0.0 0.9 15.6 0.0 0.3 0.0 1.5 34.6 0.8 0.1 0.0 0.7 0.0 0.0 6.1 19.1 9.6 75.8 0.4 7.2 0.0 0.0 7.4 0.0 2.0 0.5 0.4 1.5 229.9 0.0 0.5 0.2 0.1 0.2 0.3 0.0 5.7 20.7 1.5 3.8 1.6 9.7 0.1 0.8 7.5 0.1 0.4 CYP2A13 "CPAD, CYP2A" ENSG00000197838 "Cytochrome P450 family 2 subfamily A member 13" Q16696 19 41088451-41096195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "liver: 2.0" "Group enriched" "Detected in some" 8 "Club cells: 2.0;Early spermatids: 4.2;Late spermatids: 3.7" "Cancer enriched" "Detected in single" 5 "liver cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046713, HPA047262" Supported "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 34: Spermatids - Unknown function" "HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (9.79e-2)" "unprognostic (1.00e-1)" "unprognostic (4.51e-3)" "unprognostic (4.92e-2)" "unprognostic (1.99e-1)" "unprognostic (1.49e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CYP2A6 "CPA6, CYP2A, CYP2A3" ENSG00000255974 "Cytochrome P450 family 2 subfamily A member 6" P11509 19 40843541-40850447 "Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 171 "liver: 1612.0" "Cell type enriched" "Detected in some" 21 "Hepatocytes: 322.3" "Cancer enriched" "Detected in some" 12 "liver cancer: 281.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.1" "HPA046713, HPA047262" Supported "Intracellular and membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 15: Hepatocytes - Hemostasis" "HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (5.40e-2)" "unprognostic (2.36e-2)" "unprognostic (1.21e-1)" "unprognostic (4.10e-1)" "unprognostic (5.05e-2)" "unprognostic (2.64e-2)" "prognostic favorable (5.38e-5)" "unprognostic (4.98e-3)" "unprognostic (4.86e-2)" "unprognostic (6.23e-2)" "unprognostic (5.20e-2)" "unprognostic (1.95e-1)" "unprognostic (2.25e-2)" "unprognostic (8.83e-3)" "unprognostic (2.46e-1)" "unprognostic (3.07e-2)" "unprognostic (2.55e-1)" 0.6 0.2 0.0 0.0 0.1 0.0 9.4 0.0 0.2 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 1612.0 0.3 0.0 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.2 0.3 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.2 0.0 0.0 0.4 0.3 0.2 5.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 8.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 11.4 322.3 0.0 0.0 0.1 0.0 0.0 14.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.7 0.0 1.5 CYP2A7 CYP2A ENSG00000198077 "Cytochrome P450 family 2 subfamily A member 7" P20853 19 40875439-40882752 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 71 "liver: 152.5" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 195.3" "Group enriched" "Detected in some" 238 "breast cancer: 9.2;liver cancer: 25.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033510, HPA046713, HPA047262" Enhanced "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" "CAB033510: AB_782366, HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (2.18e-1)" "unprognostic (3.60e-2)" "unprognostic (2.65e-3)" "unprognostic (8.89e-2)" "unprognostic (1.39e-2)" "unprognostic (3.95e-1)" "unprognostic (9.21e-2)" "unprognostic (8.71e-2)" "unprognostic (3.99e-2)" "unprognostic (1.06e-2)" 0.0 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.6 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 152.5 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.6 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 24.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.2 11.0 195.3 0.0 0.0 0.1 0.8 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.9 CYP2B6 "CPB6, CYP2B, CYPIIB6" ENSG00000197408 "Cytochrome P450 family 2 subfamily B member 6" P20813 19 40991282-41018398 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "liver: 533.7" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 420.9" "Cancer enhanced" "Detected in many" "liver cancer: 28.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.6;OE19: 1.8" "Region enhanced" "Detected in single" "spinal cord: 2.3" "CAB033866, HPA048124, HPA062973" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB033866: AB_2292644, HPA048124: AB_2680274, HPA062973: AB_2684914" "unprognostic (1.86e-1)" "unprognostic (1.23e-2)" "unprognostic (1.13e-2)" "unprognostic (6.13e-2)" "unprognostic (4.59e-2)" "unprognostic (4.63e-2)" "unprognostic (4.41e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-2)" "unprognostic (1.04e-3)" "unprognostic (2.19e-1)" "unprognostic (9.43e-2)" "unprognostic (5.44e-1)" 0.0 0.0 0.2 0.2 0.2 0.5 0.1 0.6 0.3 0.0 0.3 4.7 5.1 0.1 0.0 0.0 0.0 0.7 0.1 0.3 0.1 15.1 533.7 0.4 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.8 0.0 0.1 0.2 0.0 6.7 0.6 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.0 2.6 0.1 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.5 0.2 1.8 0.1 0.0 0.1 0.1 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.2 0.4 0.3 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.0 0.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.5 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.6 0.3 0.3 0.1 0.3 0.1 0.2 0.0 0.2 0.4 0.0 0.0 1.1 0.0 0.8 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.2 7.2 1.4 1.8 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 16.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 11.4 420.9 0.0 0.0 0.1 1.6 0.0 11.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 0.0 0.0 0.1 38.3 16.9 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.1 4.3 0.7 CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 102.8;liver: 197.0;stomach 1: 67.2" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 68.8;Hepatocytes: 124.0;Proximal enterocytes: 62.5;Squamous epithelial cells: 22.8" "Cancer enhanced" "Detected in many" "liver cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.2;OE19: 1.9" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-1)" "unprognostic (9.78e-2)" "unprognostic (2.28e-1)" "unprognostic (4.22e-3)" "unprognostic (1.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (6.81e-3)" 0.3 0.0 0.0 1.6 0.1 0.0 0.3 0.2 0.1 5.3 0.0 5.9 102.8 0.1 0.0 30.9 0.0 16.3 0.0 0.1 0.0 0.3 197.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 2.5 0.0 5.4 0.0 0.0 4.4 83.1 0.1 0.1 0.0 67.2 0.1 0.1 0.3 0.0 0.0 7.1 0.2 9.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.4 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.3 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.1 17.2 3.2 0.0 0.0 0.1 0.0 6.7 0.0 1.5 0.0 0.6 0.1 0.0 0.0 2.7 0.5 6.9 0.2 0.1 68.8 1.3 0.0 0.0 1.8 124.0 0.0 0.0 0.8 2.1 2.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 9.1 3.9 0.0 0.3 0.0 62.5 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.3 22.8 1.7 1.5 0.1 0.1 5.7 0.0 CYP2C19 "CPCJ, CYP2C, P450IIC19" ENSG00000165841 "Cytochrome P450 family 2 subfamily C member 19" P33261 10 94762681-94855547 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 190.2" "Group enriched" "Detected in some" 11 "Gastric mucus-secreting cells: 3.1;Hepatocytes: 9.5;Proximal enterocytes: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, HPA074424" Supported Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA015066: AB_1847433, HPA074424: " "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.2 0.2 0.1 0.2 32.4 0.0 0.1 1.6 0.0 1.7 0.0 0.1 0.0 0.0 190.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.6 13.9 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.1 0.0 0.0 0.0 0.4 9.5 0.0 0.0 0.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 CYP2C8 CPC8 ENSG00000138115 "Cytochrome P450 family 2 subfamily C member 8" P10632 10 95036772-95069497 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 359 "liver: 2156.6" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 1834.2" "Cancer enriched" "Detected in some" 82 "liver cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013547, HPA013970, HPA015066, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA013547: AB_1847435, HPA013970: AB_1847434, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-2)" "unprognostic (1.80e-3)" "unprognostic (4.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-1)" "prognostic favorable (9.82e-4)" "unprognostic (2.85e-1)" "unprognostic (1.44e-3)" "unprognostic (2.63e-1)" "unprognostic (7.88e-2)" "unprognostic (1.39e-1)" "unprognostic (4.05e-4)" 0.3 1.8 1.7 0.0 1.9 0.2 0.3 1.4 2.1 0.3 1.4 0.4 0.2 0.1 0.3 0.1 1.1 4.6 0.3 1.8 2.2 1.4 2156.6 0.4 0.1 1.7 2.2 0.1 1.7 0.5 3.1 0.1 1.8 0.6 0.0 3.1 0.2 0.3 0.2 0.1 1.1 0.0 1.4 1.0 6.0 4.0 2.1 0.2 0.9 0.0 0.1 0.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.9 1.4 2.1 1.8 2.2 1.7 2.2 1.8 1.4 2.1 1.8 0.0 0.0 0.0 1.6 8.9 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.2 147.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 7.3 0.9 0.1 2.0 1.8 57.5 4.5 0.2 0.0 0.1 0.0 0.2 0.0 0.6 52.8 1834.2 0.0 5.0 3.7 0.1 0.0 70.9 0.0 7.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 1.2 0.5 1.2 0.0 0.0 0.1 1.0 0.8 0.9 1.7 0.0 0.0 0.3 2.1 0.6 0.0 0.0 0.0 3.3 0.0 0.2 0.2 CYP2C9 "CYP2C10, P450IIC9" ENSG00000138109 "Cytochrome P450 family 2 subfamily C member 9" P11712 10 94938658-94990091 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 1719.9" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 1704.9" "Cancer enriched" "Detected in some" 41 "liver cancer: 118.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, CAB016123, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "CAB016123: AB_629363, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.37e-1)" "unprognostic (5.68e-2)" "unprognostic (9.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.83e-2)" "prognostic favorable (2.83e-6)" "unprognostic (2.37e-1)" "unprognostic (2.05e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-4)" "unprognostic (7.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (1.24e-2)" 0.2 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.0 1.2 0.0 2.7 87.8 0.0 0.0 7.7 0.0 7.9 0.0 0.0 0.0 4.3 1719.9 0.2 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.0 0.0 0.0 2.3 46.2 0.1 0.0 0.5 18.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.6 0.2 1.8 0.0 0.0 0.0 1.5 0.0 7.6 0.0 0.8 0.7 1.1 0.0 16.0 0.0 0.7 0.0 0.2 44.4 7.4 0.0 0.0 26.7 1704.9 0.0 0.0 0.1 1.4 0.0 34.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 2.6 0.0 0.1 0.0 65.3 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.1 1.9 0.0 2.7 0.0 CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 309 "liver: 10379.8" "Cell type enriched" "Detected in many" 58 "Hepatocytes: 6272.7" "Cancer enriched" "Detected in some" 278 "liver cancer: 265.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5;myeloid DC: 6.2" "Group enriched" "Detected in many" 16 "dendritic cells: 6.2;T-cells: 2.5" "Cell line enhanced" "Detected in many" "HaCaT: 11.0;HL-60: 8.9;HMC-1: 8.9;NB-4: 24.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced Approved "Endoplasmic reticulum,Mitochondria" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Mitochondria" "HPA009128: AB_1078613, HPA029564: AB_10602213" "unprognostic (6.32e-2)" "unprognostic (1.51e-2)" "unprognostic (3.83e-5)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (6.36e-3)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-4)" "unprognostic (1.72e-1)" "unprognostic (8.36e-2)" "unprognostic (3.78e-1)" "unprognostic (9.59e-2)" 2.8 2.9 5.4 0.6 5.4 0.8 3.0 9.1 7.5 4.9 3.0 5.0 1.4 4.5 8.3 16.7 5.5 2.5 2.1 5.5 5.5 9.1 10379.8 2.6 2.0 6.1 5.5 4.1 12.4 0.6 4.1 1.4 6.7 5.3 1.2 11.5 3.6 6.1 2.8 13.8 2.2 2.2 5.0 7.2 6.7 3.7 6.3 1.7 4.0 0.9 33.6 3.5 3.2 7.5 0.1 0.0 0.3 1.0 3.5 1.9 0.7 1.6 4.5 0.0 0.3 0.0 2.7 1.4 0.2 0.5 0.0 11.0 0.0 0.2 0.4 0.3 1.5 1.8 0.2 1.3 0.6 8.9 8.9 1.0 0.2 0.0 0.7 1.9 0.0 3.1 0.6 0.4 1.0 0.7 0.6 24.0 6.4 4.3 0.4 0.4 6.1 0.0 2.0 0.0 0.0 0.0 4.2 0.0 0.6 0.2 0.3 0.9 0.0 1.4 0.4 2.3 1.0 2.2 1.0 3.0 1.5 7.4 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.1 0.6 6.2 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 5.4 5.4 9.1 7.5 5.5 5.5 6.1 5.5 6.7 5.0 6.3 7.5 0.8 0.0 1.1 5.5 9.2 2.3 0.2 0.7 0.6 5.7 0.6 0.5 2.8 48.6 1.9 0.0 2.1 0.0 0.4 0.1 0.0 1.6 2.1 0.6 0.8 4.6 0.0 67.6 6.7 1.3 0.1 1.1 1.5 0.5 1.3 0.7 67.1 6272.7 0.0 8.4 5.3 0.0 0.0 108.0 2.8 2.1 1.5 0.3 0.0 1.9 0.4 0.7 0.0 2.0 2.2 3.2 0.0 2.6 0.3 0.6 0.0 0.6 2.2 5.8 0.0 0.2 0.6 4.1 4.2 2.0 7.5 0.1 5.7 0.2 0.0 0.0 CYP2F1 CYP2F ENSG00000197446 "Cytochrome P450 family 2 subfamily F member 1" P24903 19 41114432-41128381 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 1.4;salivary gland: 1.0;testis: 2.1" "Cell type enriched" "Detected in some" 4 "Club cells: 67.4" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "HMC-1: 2.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 71: Testis - DNA repair" "Cluster 3: HMC-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.04e-1)" "unprognostic (8.79e-2)" "unprognostic (4.63e-1)" "unprognostic (4.60e-2)" "unprognostic (2.54e-1)" "unprognostic (7.29e-3)" "unprognostic (6.23e-3)" "unprognostic (2.87e-2)" "unprognostic (3.91e-2)" "unprognostic (1.58e-6)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (9.90e-2)" "unprognostic (1.50e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.5 0.0 67.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.1 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 16.5 0.0 0.0 0.0 1.6 8.0 5.3 1.5 0.0 0.0 0.6 0.0 0.0 0.1 CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.7;intestine: 83.4;liver: 146.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 91.4;Cytotrophoblasts: 116.2;Hepatocytes: 58.3;Oligodendrocytes: 68.5;Proximal enterocytes: 134.6;Syncytiotrophoblasts: 240.9" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "OE19: 16.9;RT4: 62.3;SK-BR-3: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" 1.2 0.4 18.3 1.2 22.1 0.1 9.3 23.6 19.1 2.3 8.4 19.0 34.1 1.0 0.8 13.1 0.9 2.0 89.7 14.7 19.4 3.0 146.2 1.4 0.2 20.7 20.7 0.0 2.2 0.0 0.9 22.3 18.9 3.3 21.3 3.5 14.5 0.7 25.3 8.9 83.4 1.8 20.2 0.1 4.7 0.6 28.0 0.5 0.1 6.4 0.7 5.8 3.6 21.8 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.7 0.1 1.2 0.3 2.8 0.0 0.8 0.0 3.5 0.9 0.0 0.9 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.1 0.5 0.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 3.2 0.0 0.0 1.5 16.9 2.6 0.0 6.3 0.0 3.4 62.3 0.9 3.8 0.1 16.4 0.6 0.1 4.1 0.0 0.0 2.2 2.5 0.0 0.9 1.9 0.1 0.0 0.5 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.6 0.8 0.3 0.2 0.0 0.4 2.9 2.6 0.0 0.4 0.0 0.6 0.0 0.4 18.3 22.1 23.6 19.1 14.7 19.4 20.7 20.7 18.9 20.2 28.0 21.8 0.0 3.2 4.1 35.6 0.7 0.4 1.7 5.5 7.4 0.0 5.1 3.0 91.4 11.5 28.9 0.0 0.0 116.2 0.1 26.4 0.0 9.5 22.7 3.1 1.7 1.3 9.0 0.0 0.1 0.9 9.3 2.3 4.1 7.7 0.0 1.5 0.0 58.3 7.0 0.0 0.4 18.7 6.1 0.8 0.3 23.3 0.0 0.2 0.0 1.9 0.6 12.5 0.0 29.7 68.5 2.0 18.1 0.0 0.3 1.5 134.6 2.5 20.1 0.9 0.0 0.7 1.0 0.3 0.2 7.3 2.3 240.9 0.2 0.4 24.1 2.1 CYP2R1 ENSG00000186104 "Cytochrome P450 family 2 subfamily R member 1" Q6VVX0 11 14877440-14892231 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 176.3;Late spermatids: 106.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 26.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042949 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA042949: AB_2678237" "unprognostic (1.62e-2)" "unprognostic (1.82e-2)" "unprognostic (5.90e-2)" "unprognostic (1.63e-3)" "unprognostic (2.67e-1)" "unprognostic (2.19e-1)" "unprognostic (3.23e-2)" "unprognostic (7.73e-2)" "unprognostic (1.70e-1)" "unprognostic (3.90e-2)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.01e-1)" "unprognostic (1.81e-1)" "unprognostic (1.46e-1)" "unprognostic (1.44e-2)" 2.5 1.8 1.6 3.1 1.9 3.0 4.1 4.9 2.4 2.6 0.5 3.7 4.6 2.2 3.2 4.6 1.8 1.6 2.2 1.6 2.1 1.8 2.2 2.5 3.0 1.7 1.5 2.0 5.2 1.5 2.6 1.0 1.8 2.8 3.3 3.3 4.5 1.4 2.8 6.9 4.4 1.5 1.5 3.0 5.0 4.3 1.6 2.4 1.9 1.6 2.9 3.0 3.3 2.3 6.1 3.7 3.6 1.5 1.5 2.5 0.0 2.1 1.1 1.2 1.3 4.3 6.8 7.6 1.6 0.4 4.7 0.0 1.2 2.8 0.5 6.3 5.8 3.4 4.7 0.3 5.4 5.9 3.4 2.4 10.6 0.0 4.4 1.1 1.4 9.3 5.1 26.0 0.8 1.6 6.5 11.9 3.4 4.4 3.5 4.6 2.6 11.6 1.4 0.7 3.0 4.7 4.5 5.4 5.2 2.3 4.0 2.2 3.8 3.6 4.4 2.2 2.7 12.8 16.1 9.0 5.0 7.6 3.3 2.4 2.0 1.6 3.0 1.9 4.7 1.6 2.5 1.9 1.7 2.8 3.5 3.0 0.3 2.1 2.3 2.0 3.6 1.2 1.6 1.9 4.9 2.4 1.6 2.1 1.7 1.5 1.8 1.5 1.6 2.3 4.4 12.8 4.8 8.5 15.4 5.9 13.9 9.3 12.5 1.9 7.0 5.8 4.3 8.6 7.4 5.5 6.2 0.3 9.8 10.1 5.9 8.1 176.3 1.9 3.3 6.7 6.7 4.6 13.1 16.9 0.2 4.4 14.8 3.9 3.8 7.8 5.0 6.0 5.9 1.7 18.4 5.5 0.0 7.6 12.6 106.7 2.1 7.7 14.2 13.1 6.1 5.0 13.4 14.6 13.3 11.3 2.9 4.1 11.9 6.4 12.6 6.2 2.8 5.0 13.1 3.2 4.9 23.8 20.2 20.4 6.7 0.0 16.4 6.7 8.8 6.1 CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 101.3;stomach 1: 120.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.0;Gastric mucus-secreting cells: 110.6;Intestinal goblet cells: 29.2;Langerhans cells: 73.0;Proximal enterocytes: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.7;myeloid DC: 84.4" "Group enriched" "Detected in many" 131 "dendritic cells: 84.4;monocytes: 24.7" "Cell line enhanced" "Detected in many" "A549: 99.4;CACO-2: 49.8;HaCaT: 50.3;NTERA-2: 69.6;OE19: 158.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA049227: AB_2680681, HPA069248: AB_2732128" "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" 1.8 1.1 1.4 6.7 1.4 1.8 0.9 3.1 1.5 2.7 1.2 26.7 101.3 0.5 0.2 14.5 6.3 5.5 0.5 1.3 4.1 1.1 1.4 7.1 1.7 6.3 10.0 0.3 0.6 0.7 1.2 1.6 6.1 1.3 18.6 0.2 5.0 0.9 0.2 3.7 65.3 1.7 2.2 6.1 120.4 0.8 3.6 3.2 0.6 0.2 13.2 3.6 4.0 2.5 3.8 99.4 0.0 0.1 0.0 0.0 4.5 0.6 0.8 1.0 0.2 49.8 13.6 0.2 10.4 0.7 0.1 50.3 16.6 25.0 0.4 0.0 0.3 12.9 5.1 19.1 19.4 0.0 0.4 0.8 1.4 1.4 0.8 0.2 0.8 4.3 5.8 0.2 0.0 2.0 0.3 0.2 69.6 158.6 12.5 0.2 0.0 0.9 1.5 20.4 0.1 0.6 9.1 0.0 0.0 27.8 12.2 4.7 10.6 0.1 4.0 1.7 0.0 0.5 0.0 0.0 0.5 2.1 0.1 0.0 24.7 0.0 0.0 5.9 0.4 0.0 0.0 0.1 84.4 0.0 0.0 0.0 0.2 0.1 3.7 3.2 0.0 11.4 1.4 1.4 3.1 1.5 1.3 4.1 6.3 10.0 6.1 2.2 3.6 2.5 0.3 0.0 6.9 1.0 0.7 2.5 2.0 18.2 23.3 0.0 0.1 0.3 1.2 0.0 7.6 1.8 0.0 24.9 0.1 31.0 0.0 0.7 0.3 7.4 0.3 0.4 0.0 0.0 0.4 1.0 1.1 0.8 110.6 0.3 1.3 0.1 0.4 0.0 14.5 0.0 0.5 29.2 0.0 5.7 73.0 0.0 0.0 16.0 0.0 1.0 7.2 0.0 0.0 0.5 0.1 23.7 22.3 0.0 0.4 0.5 50.7 0.2 10.8 0.0 0.0 0.3 0.9 0.1 0.4 4.0 2.8 10.3 0.3 0.0 14.1 0.5 CYP2W1 "FLJ20359, MGC34287" ENSG00000073067 "Cytochrome P450 family 2 subfamily W member 1" Q8TAV3 7 983181-989640 "Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 19.1;intestine: 6.1;skin 1: 10.5" "Cell type enriched" "Detected in some" 7 "Enteroendocrine cells: 98.5" "Group enriched" "Detected in many" 5 "colorectal cancer: 25.3;stomach cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 13.5;Hep G2: 49.8" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.09e-3)" "unprognostic (1.94e-2)" "unprognostic (2.75e-2)" "unprognostic (1.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.22e-1)" "unprognostic (1.97e-1)" "unprognostic (2.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (6.26e-2)" "unprognostic (2.72e-5)" "unprognostic (7.52e-2)" "unprognostic (1.34e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.85e-4)" 0.1 19.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.4 0.0 0.9 6.1 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.3 1.0 0.1 2.1 0.5 0.2 0.3 0.2 0.0 10.5 1.0 0.0 0.0 0.4 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.2 49.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 2.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.6 4.3 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 4.0 2.3 1.5 0.0 0.6 0.0 0.0 0.5 0.0 2.6 0.0 0.0 1.1 0.0 3.7 0.0 0.1 0.1 0.1 0.0 0.3 98.5 0.0 0.0 0.9 0.6 10.2 0.0 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 13.6 0.0 0.0 0.9 0.0 1.8 0.3 0.0 0.0 0.1 10.5 0.0 0.0 0.0 0.1 3.3 0.0 0.1 1.2 1.1 0.0 3.3 0.6 0.0 0.8 0.3 0.2 0.1 0.0 4.4 1.9 0.2 4.4 11.4 3.7 CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 177.7;liver: 276.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 377.4;Distal enterocytes: 382.7;Gastric mucus-secreting cells: 506.6;Hepatocytes: 454.5;Paneth cells: 451.6;Proximal enterocytes: 1074.6;Urothelial cells: 380.4" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 9.7;Hep G2: 7.9;OE19: 28.3" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favorable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" 3.3 14.4 0.1 3.8 0.4 0.6 6.5 0.8 0.9 5.1 0.4 28.4 127.3 3.1 3.0 22.1 3.1 32.7 1.0 0.3 0.0 10.6 276.1 9.2 1.4 0.6 0.0 0.8 47.0 0.0 0.9 0.4 0.4 21.6 21.0 0.7 2.9 5.7 0.9 20.5 177.7 1.1 0.0 0.8 86.5 0.4 0.0 2.1 1.0 0.0 3.2 10.4 13.1 0.5 1.6 3.3 1.6 1.9 0.4 0.6 0.5 1.5 0.0 0.0 0.0 9.7 7.4 1.0 1.5 0.0 1.2 1.2 0.0 0.0 0.0 1.8 1.2 1.2 0.7 7.9 0.1 2.0 0.6 0.0 2.1 0.0 0.0 1.4 0.0 0.9 3.3 2.0 0.0 0.3 2.6 3.8 0.4 28.3 0.8 0.6 1.6 2.2 0.4 1.5 1.2 1.7 0.9 0.8 3.2 1.6 0.5 0.7 1.2 1.8 1.6 1.6 1.2 1.0 2.6 1.7 1.6 2.6 1.5 0.4 0.3 0.4 0.4 0.3 0.9 0.2 0.6 0.6 0.2 0.1 0.4 0.5 0.5 0.4 0.2 0.3 0.5 0.2 0.1 0.4 0.8 0.9 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.5 0.9 12.8 14.8 1.3 4.8 46.1 112.7 31.0 59.7 13.7 1.1 0.4 1.3 377.4 27.3 3.7 12.5 1.7 1.7 382.7 0.0 63.4 2.0 3.1 2.2 6.3 54.6 21.7 8.6 50.7 1.2 8.5 506.6 10.3 10.1 1.8 8.2 454.5 0.6 8.4 11.0 140.5 6.1 9.5 4.5 0.5 2.5 4.1 3.6 2.8 4.9 4.0 10.3 7.1 6.5 80.1 451.6 2.6 6.4 156.3 1074.6 10.8 12.1 21.6 0.0 2.5 3.4 15.1 6.4 107.3 59.0 1.5 7.5 3.1 139.8 380.4 CYP4F2 ENSG00000186115 "Cytochrome P450 family 4 subfamily F member 2" P78329 19 15878023-15898077 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 80.2;kidney: 40.9;liver: 166.7" "Group enriched" "Detected in some" 4 "Hepatocytes: 139.7;Proximal enterocytes: 204.6" "Cancer enriched" "Detected in some" 9 "liver cancer: 29.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 19 "basophil: 8.1" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.1" "Cell line enriched" "Detected in single" 4 "Hep G2: 3.8" "Low region specificity" "Detected in all" "HPA014048, HPA017265, HPA058960" Supported "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA014048: AB_1847452, HPA017265: AB_1847451, HPA058960: AB_2683862" "unprognostic (7.46e-3)" "unprognostic (3.58e-1)" "unprognostic (3.01e-1)" "unprognostic (9.39e-2)" "unprognostic (1.74e-1)" "unprognostic (2.87e-2)" "unprognostic (4.55e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (4.64e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (8.69e-4)" "unprognostic (3.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.79e-3)" 0.0 0.0 0.1 0.1 0.1 1.1 0.2 0.1 0.3 0.1 0.5 2.2 79.9 0.0 25.8 0.2 0.0 3.3 0.0 0.2 0.1 40.9 166.7 0.0 0.1 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.1 6.6 0.9 0.0 0.0 0.1 0.0 0.8 80.2 0.0 0.3 0.1 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.4 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.0 12.3 1.9 0.1 5.8 0.0 0.0 0.1 1.8 5.3 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 1.4 139.7 0.0 0.0 0.0 8.9 0.0 3.8 0.0 18.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.5 204.6 37.7 0.0 0.0 0.0 0.0 0.7 0.1 0.4 0.0 0.1 0.0 0.2 0.1 5.6 0.2 CYP7A1 CYP7 ENSG00000167910 "Cytochrome P450 family 7 subfamily A member 1" P22680 8 58490178-58500163 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 80 "liver: 49.5" "Cell type enriched" "Detected in single" 17 "Hepatocytes: 7.0" "Cancer enriched" "Detected in single" 96 "liver cancer: 28.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (5.20e-2)" "unprognostic (1.93e-2)" "unprognostic (1.77e-2)" "prognostic favorable (3.19e-4)" "unprognostic (7.60e-2)" "unprognostic (5.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-1)" "unprognostic (8.43e-3)" "unprognostic (3.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.51e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CYTL1 "C17, C4orf4" ENSG00000170891 "Cytokine like 1" Q9NRR1 4 5014586-5019458 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.0" "Cell type enhanced" "Detected in some" "Adipocytes: 14.1;Endothelial cells: 32.0;Erythroid cells: 86.6;Fibroblasts: 16.8;Hofbauer cells: 15.5;Microglial cells: 23.4" "Group enriched" "Detected in many" 5 "glioma: 21.0;melanoma: 20.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "NK-cell: 27.0" "Lineage enriched" "Detected in many" 11 "NK-cells: 27.0" "Cell line enhanced" "Detected in some" "HEL: 194.1;HUVEC TERT2: 152.3;NB-4: 382.2;WM-115: 89.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067201 Supported "Nuclear membrane,Endoplasmic reticulum" "Secreted in other tissues" NA NA 270000 "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear membrane, Endoplasmic reticulum" "HPA067201: AB_2732760" "unprognostic (2.35e-2)" "unprognostic (9.01e-3)" "unprognostic (3.56e-1)" "unprognostic (3.76e-2)" "unprognostic (1.14e-1)" "unprognostic (2.71e-1)" "unprognostic (2.09e-2)" "unprognostic (1.44e-1)" "unprognostic (7.10e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (7.43e-4)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.18e-1)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.25e-4)" 5.8 1.9 2.1 1.8 2.5 13.9 6.9 2.8 3.9 12.9 3.1 5.5 0.6 9.5 1.3 4.8 7.9 4.6 1.5 2.6 2.7 1.0 0.3 4.9 4.5 4.2 3.0 1.7 1.2 1.2 1.6 46.0 3.9 10.8 1.4 0.2 4.3 14.4 0.5 3.2 2.4 4.0 3.3 1.2 4.7 0.3 3.4 4.5 5.8 0.2 4.9 12.0 7.3 4.8 0.1 0.0 0.1 0.0 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.1 0.1 0.0 0.9 0.0 0.0 5.0 0.0 2.7 0.0 0.0 152.3 0.0 0.0 7.5 0.0 0.0 0.0 382.2 0.7 0.0 0.0 5.7 7.7 0.2 0.0 0.0 0.1 8.8 0.3 0.0 24.5 0.2 0.0 0.0 52.7 0.0 34.6 0.1 0.0 1.0 0.2 0.4 0.0 4.8 89.6 2.5 1.2 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.7 0.1 27.0 0.0 0.4 0.0 0.9 2.1 2.5 2.8 3.9 2.6 2.7 4.2 3.0 3.9 3.3 3.4 4.8 14.1 0.0 0.5 0.0 1.2 2.8 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.4 2.3 0.0 0.0 0.2 0.4 0.3 0.3 32.0 0.0 86.6 0.0 0.0 0.4 16.8 0.0 0.3 8.9 0.2 0.7 0.0 15.5 0.0 0.0 0.0 0.0 0.8 2.9 0.0 0.0 4.7 8.8 23.4 0.6 0.0 3.1 0.5 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 2.3 0.8 0.1 0.0 0.3 1.6 0.5 0.5 8.6 0.0 0.6 D2HGDH "D2HGD, FLJ42195, MGC25181" ENSG00000180902 "D-2-hydroxyglutarate dehydrogenase" Q8N465 2 241734602-241768816 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.5" "Group enriched" "Detected in many" 4 "B-cells: 2.5;T-cells: 1.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056216, HPA060548" Uncertain Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA056216: AB_2683070, HPA060548: AB_2732650" "unprognostic (2.85e-1)" "unprognostic (3.35e-2)" "unprognostic (6.98e-3)" "unprognostic (7.88e-2)" "unprognostic (2.42e-1)" "prognostic favorable (9.11e-4)" "unprognostic (2.49e-3)" "unprognostic (1.67e-2)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (7.82e-3)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (9.60e-2)" "unprognostic (3.05e-2)" 11.5 17.7 6.9 11.2 8.0 18.6 7.6 6.2 7.3 10.5 14.9 16.6 11.4 11.8 13.0 15.0 16.1 14.1 11.4 6.6 6.1 15.9 19.1 10.6 12.0 8.4 6.9 14.8 16.6 15.2 10.5 8.9 6.6 14.6 14.6 3.2 18.7 14.9 33.8 39.4 14.9 9.3 6.1 15.1 14.7 4.9 7.3 7.4 18.0 23.7 11.5 8.9 9.6 8.6 10.2 10.5 6.2 9.6 14.7 7.9 21.5 9.7 12.2 9.6 7.7 11.8 21.9 8.3 4.4 9.7 11.0 23.2 5.9 7.8 4.0 8.8 5.7 15.9 11.3 20.5 8.2 19.0 12.1 14.1 13.7 7.6 7.3 18.5 9.5 13.1 20.7 5.3 8.6 16.8 16.0 19.7 3.0 13.8 20.8 19.5 6.9 16.2 17.6 36.7 20.4 7.2 9.4 23.8 6.6 4.1 14.7 6.7 4.1 14.9 5.6 7.9 5.8 9.9 1.9 13.4 10.3 20.8 10.0 0.0 0.2 0.0 0.2 0.2 0.4 2.5 0.1 1.0 0.4 0.1 0.6 0.2 0.0 0.0 0.3 0.1 0.8 0.1 6.9 8.0 6.2 7.3 6.6 6.1 8.4 6.9 6.6 6.1 7.3 8.6 10.4 9.6 14.3 33.3 10.4 19.8 23.5 13.7 25.6 14.3 22.8 22.7 10.6 25.8 16.3 18.4 14.6 44.0 13.0 40.9 23.5 10.5 3.6 12.5 13.2 9.7 31.8 6.9 7.1 8.7 15.9 15.7 23.0 19.2 5.7 28.0 13.2 46.0 18.2 11.8 9.9 56.4 14.2 10.8 7.5 4.8 16.8 12.6 3.6 15.9 5.3 37.4 8.2 28.6 12.8 6.7 32.0 18.0 15.0 19.3 26.4 31.4 13.9 12.0 6.6 14.0 11.7 2.1 7.0 25.7 14.8 22.6 14.0 27.0 49.9 22.2 DAB2IP "AF9Q34, AIP1, DIP1/2, KIAA1743" ENSG00000136848 "DAB2 interacting protein" Q5VWQ8 9 121567057-121785530 "Disease related genes, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Cell cycle, Growth regulation, Immunity, Inflammatory response, Innate immunity, Stress response, Unfolded protein response" "Developmental protein, GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 81.7;HDLM-2: 64.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "unprognostic (3.82e-2)" "unprognostic (2.79e-1)" "unprognostic (2.62e-2)" "unprognostic (4.99e-3)" "unprognostic (1.52e-1)" "unprognostic (1.90e-1)" "unprognostic (2.31e-1)" "unprognostic (1.07e-1)" "unprognostic (1.08e-1)" "unprognostic (1.49e-2)" "unprognostic (3.09e-1)" "unprognostic (1.87e-1)" "prognostic favorable (4.00e-15)" "unprognostic (1.00e-2)" "unprognostic (2.07e-1)" "unprognostic (1.75e-2)" "unprognostic (2.81e-2)" 24.3 17.8 26.8 11.3 44.5 0.3 28.3 91.5 37.7 22.4 15.7 40.7 18.5 41.6 5.6 26.0 21.8 13.9 35.3 29.9 24.1 39.3 13.5 29.6 3.9 33.0 23.6 29.0 19.1 9.9 15.3 14.5 23.4 24.8 14.8 11.7 38.4 23.9 47.4 28.7 21.3 21.9 24.5 23.6 30.0 23.0 34.9 8.5 19.1 17.9 3.2 23.6 20.5 23.3 18.2 21.0 17.5 16.0 3.4 2.6 28.7 13.9 32.5 10.3 5.9 15.2 15.3 0.0 17.1 13.5 14.5 81.7 16.3 47.6 2.6 64.6 9.9 0.3 22.9 27.4 4.8 2.8 0.1 1.4 32.4 3.6 7.1 9.4 16.0 1.6 0.3 0.2 3.4 18.5 13.1 3.9 19.0 54.2 6.9 6.1 12.5 28.6 10.6 27.3 17.7 33.2 7.5 47.6 25.9 10.1 52.9 2.3 16.2 12.2 16.0 4.0 11.1 0.2 0.3 1.2 1.4 0.5 14.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 44.5 91.5 37.7 29.9 24.1 33.0 23.6 23.4 24.5 34.9 23.3 39.4 44.8 11.7 21.9 1.1 5.0 18.9 20.8 21.1 20.6 16.3 22.5 23.7 30.0 12.6 11.0 0.0 6.0 0.6 49.4 9.8 35.6 5.8 19.2 13.9 29.3 6.0 0.0 31.0 32.1 9.9 11.4 14.3 33.9 0.0 18.8 14.6 11.0 1.1 15.2 20.0 17.2 16.2 0.3 2.1 8.6 12.8 1.2 14.2 22.5 0.7 41.9 0.0 23.6 10.7 40.6 11.7 9.8 1.2 24.0 18.4 8.3 5.7 2.7 6.6 16.9 21.7 5.3 13.1 15.5 2.8 26.5 2.0 14.7 23.9 19.2 DAG1 "156DAG, A3a, AGRNR, DAG" ENSG00000173402 "Dystroglycan 1" Q14118 3 49468703-49535618 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 207.9;Skeletal myocytes: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 280.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001960, CAB016353, HPA070563" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 84000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" Nucleoplasm "CAB001960: , CAB016353: AB_627292, HPA070563: " "unprognostic (1.58e-1)" "unprognostic (5.14e-1)" "unprognostic (6.71e-3)" "unprognostic (3.32e-1)" "unprognostic (7.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.67e-1)" "unprognostic (3.27e-2)" "unprognostic (8.18e-2)" "unprognostic (3.91e-2)" "unprognostic (5.70e-3)" "unprognostic (1.10e-1)" "prognostic favorable (2.59e-4)" "unprognostic (9.22e-2)" "unprognostic (1.99e-2)" "unprognostic (7.43e-2)" "unprognostic (1.57e-2)" 25.2 22.0 31.5 17.9 32.6 5.4 26.6 30.7 30.7 26.2 25.5 38.8 24.0 32.1 16.2 28.3 31.8 26.4 68.9 30.1 28.9 28.1 43.0 31.8 9.4 33.3 31.4 24.6 51.4 44.3 18.6 77.0 28.6 29.5 30.6 9.8 31.8 37.9 93.8 28.5 24.0 45.9 30.2 12.6 32.0 26.9 34.1 10.5 25.5 95.7 14.3 27.8 22.0 31.2 92.3 92.4 61.9 152.3 80.3 38.8 280.9 63.9 93.7 108.0 69.0 74.2 96.0 13.0 62.2 103.2 87.6 168.4 55.6 81.2 67.2 12.7 18.6 9.6 84.3 87.2 35.5 11.2 17.4 33.3 72.5 100.3 33.3 96.7 97.1 15.3 14.5 9.8 31.2 75.5 10.1 8.1 66.4 110.0 31.2 5.5 60.5 22.3 82.5 126.4 21.8 45.2 74.8 206.0 105.5 170.3 171.6 22.8 51.8 39.1 63.9 76.0 91.4 11.0 24.2 8.1 50.4 12.6 245.9 2.3 1.2 0.7 1.1 1.3 1.2 1.2 0.9 0.9 0.7 1.0 1.0 1.0 2.2 1.1 2.5 1.3 0.7 1.4 31.5 32.6 30.7 30.7 30.1 28.9 33.3 31.4 28.6 30.2 34.1 31.2 19.0 54.5 18.4 32.0 4.0 14.3 8.0 31.7 17.1 7.4 36.1 46.4 56.6 30.0 20.6 35.0 4.2 116.4 5.8 37.3 1.9 32.4 30.0 30.2 17.3 20.9 33.0 14.3 15.6 79.6 118.4 26.1 37.8 37.9 7.0 207.9 16.8 59.9 21.2 3.3 16.5 29.7 14.2 8.6 7.0 20.0 21.5 6.3 33.8 9.4 5.6 27.1 5.2 19.6 10.7 57.2 21.4 36.9 5.1 14.4 18.9 7.6 23.2 8.7 46.0 326.1 36.2 7.1 19.9 19.0 17.0 95.9 5.9 10.0 29.2 10.2 DAND5 "CER2, CKTSF1B3, Coco, DANTE, DTE, FLJ38607, GREM3" ENSG00000179284 "DAN domain BMP antagonist family member 5" Q8N907 19 12965159-12974760 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "heart muscle: 8.5" "Cell type enriched" "Detected in some" 7 "Cardiomyocytes: 17.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 16 "SH-SY5Y: 19.8" "Not detected" "Not detected" "HPA043493, HPA049472" Uncertain Approved Mitochondria "Secreted in other tissues" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043493: AB_2732505, HPA049472: AB_2680781" "unprognostic (1.18e-2)" "unprognostic (4.63e-2)" "unprognostic (7.51e-2)" "unprognostic (4.63e-2)" "unprognostic (3.82e-2)" "unprognostic (8.71e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-1)" "unprognostic (5.95e-3)" "unprognostic (7.27e-3)" "unprognostic (8.17e-2)" "unprognostic (2.15e-1)" "unprognostic (2.48e-10)" "unprognostic (4.43e-1)" "unprognostic (2.48e-2)" "unprognostic (6.77e-2)" "unprognostic (1.37e-1)" 0.1 0.9 0.4 0.1 0.4 0.7 0.3 0.9 0.4 0.1 1.6 2.0 0.2 0.1 0.2 0.1 0.1 0.3 8.5 0.4 0.3 0.1 0.0 0.1 0.1 0.5 0.2 0.1 0.2 0.8 0.1 0.0 0.7 0.1 0.3 0.7 0.4 0.0 0.1 0.3 0.3 0.3 0.2 0.0 0.3 0.3 0.5 0.1 0.2 0.2 0.0 0.1 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.4 0.0 0.8 0.3 0.0 0.0 0.2 0.2 0.0 0.3 0.0 0.2 0.0 0.7 0.4 1.2 0.0 0.4 0.3 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.1 0.0 1.0 19.8 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.1 1.2 0.1 0.4 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.4 1.5 0.4 0.1 0.4 0.0 0.1 0.4 0.4 0.9 0.4 0.4 0.3 0.5 0.2 0.7 0.2 0.5 0.8 0.5 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.7 1.3 17.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.4 0.5 0.0 0.0 0.1 0.4 0.1 0.4 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.3 0.3 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.6 0.0 2.1 0.5 0.1 0.2 0.3 0.3 0.0 0.1 0.1 0.5 0.1 DAO "DAAO, DAMOX" ENSG00000110887 "D-amino acid oxidase" P14920 12 108858932-108901043 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 71.4;kidney: 90.3;liver: 149.9" "Group enriched" "Detected in some" 8 "Hepatocytes: 46.1;Proximal tubular cells: 86.8" "Cancer enriched" "Detected in some" 9 "liver cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.1" "Group enriched" "Detected in some" 10 "cerebellum: 66.4;pons and medulla: 20.2" "Low region specificity" "Detected in all" "HPA038653, HPA038654" Enhanced "Intracellular and membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038653: AB_10673016, HPA038654: AB_10673285" "unprognostic (1.50e-1)" "unprognostic (5.61e-2)" "unprognostic (1.43e-1)" "unprognostic (2.91e-1)" "unprognostic (2.18e-1)" "unprognostic (2.99e-2)" "unprognostic (2.31e-3)" "unprognostic (8.02e-2)" "unprognostic (2.88e-2)" "unprognostic (9.59e-2)" "unprognostic (9.07e-2)" "unprognostic (7.13e-2)" "prognostic favorable (4.11e-4)" "unprognostic (3.44e-3)" "unprognostic (8.96e-2)" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" 0.1 0.0 0.9 0.0 6.9 0.0 0.0 71.4 1.6 0.0 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 3.3 90.3 149.9 0.2 0.0 41.9 14.8 0.0 0.2 0.0 0.0 0.0 29.5 0.0 2.0 12.0 0.0 0.0 0.0 0.0 0.0 0.1 44.0 0.1 0.1 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 59.1 0.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 6.9 71.4 1.6 0.8 3.3 41.9 14.8 29.5 44.0 4.3 59.1 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.7 0.0 4.6 3.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 46.1 0.2 0.0 1.2 0.0 0.0 0.8 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.7 0.0 0.5 0.1 0.0 1.2 0.0 0.0 0.0 0.0 86.8 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 0.4 0.0 0.2 0.0 DAZAP2 KIAA0058 ENSG00000183283 "DAZ associated protein 2" Q15038 12 51238724-51271362 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045940 Supported "Nuclear speckles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA045940: AB_2679506" "unprognostic (1.00e-2)" "unprognostic (3.13e-2)" "unprognostic (7.35e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "unprognostic (5.47e-2)" "unprognostic (4.75e-3)" "unprognostic (8.43e-2)" "unprognostic (4.75e-2)" "unprognostic (3.30e-1)" "unprognostic (5.80e-2)" "unprognostic (1.42e-1)" "prognostic favorable (3.94e-9)" "unprognostic (1.79e-1)" "unprognostic (2.40e-1)" "unprognostic (3.04e-1)" "unprognostic (5.84e-3)" 136.4 115.7 112.2 187.5 125.3 613.5 154.0 136.6 124.4 150.5 109.8 206.2 194.9 131.6 122.5 129.9 180.5 168.0 202.1 105.1 125.9 251.4 198.4 193.2 220.6 132.7 119.8 114.1 116.5 227.3 30.7 79.5 134.4 152.8 215.5 75.2 140.7 171.8 113.5 121.4 200.5 148.4 129.8 224.3 174.3 52.7 116.5 213.2 209.8 106.7 241.5 190.3 76.3 151.5 159.8 209.0 95.4 92.2 201.1 171.5 57.6 104.6 208.9 187.7 162.8 155.9 239.0 153.2 262.2 209.9 130.0 147.8 134.2 178.4 189.2 167.3 160.2 227.1 129.7 91.0 216.4 265.5 350.2 220.5 252.1 175.3 147.2 207.2 234.8 118.8 141.6 303.1 155.4 252.6 219.8 145.6 19.6 109.2 58.7 123.2 144.7 165.3 244.9 260.2 103.3 101.0 159.3 137.9 121.3 56.7 190.5 382.7 195.7 111.1 102.4 136.9 132.6 231.5 237.5 158.6 161.2 175.0 66.9 2018.1 2144.1 3354.3 1055.9 1770.0 979.3 1090.7 962.8 1037.9 1354.1 1068.7 1063.1 918.3 3499.5 1045.4 1727.1 875.9 1420.3 4885.3 112.2 125.3 136.6 124.4 105.1 125.9 132.7 119.8 134.4 129.8 116.5 151.5 116.7 144.2 205.1 19.6 271.9 113.8 201.2 144.6 167.9 50.6 127.7 88.5 114.3 165.8 127.9 235.4 58.4 55.8 167.4 337.2 266.1 158.6 28.1 115.1 87.2 138.3 126.3 155.6 16.8 194.7 53.5 108.0 171.8 142.1 182.2 72.2 157.1 177.1 209.4 67.3 16.8 230.6 140.4 444.4 214.2 85.6 117.4 282.0 135.2 19.7 324.4 88.7 221.4 15.6 43.9 198.0 275.8 95.5 169.5 179.9 233.3 292.7 155.9 55.2 46.0 63.2 130.4 39.4 35.4 153.5 133.3 124.9 249.6 72.8 182.4 268.7 DAZL "DAZH, DAZL1, DAZLA, MGC26406, SPGYLA" ENSG00000092345 "Deleted in azoospermia like" Q92904 3 16586792-16670306 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 79 "testis: 79.6" "Cell type enhanced" "Detected in some" "Early spermatids: 64.1;Late spermatids: 41.2;Spermatocytes: 257.9;Spermatogonia: 143.1" "Cancer enriched" "Detected in single" 51 "testis cancer: 13.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HAP1: 18.8" "HPA019777, HPA047113" Enhanced NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA019777: AB_1847495, HPA047113: AB_2679936" "unprognostic (5.61e-2)" "unprognostic (5.27e-3)" "unprognostic (2.80e-1)" "unprognostic (5.85e-2)" "unprognostic (2.32e-3)" "unprognostic (2.60e-2)" "unprognostic (6.34e-2)" "unprognostic (4.91e-2)" "unprognostic (9.69e-2)" "unprognostic (7.79e-2)" "unprognostic (2.04e-1)" "unprognostic (3.47e-1)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 79.6 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 41.2 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 257.9 143.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 DBH DBM ENSG00000123454 "Dopamine beta-hydroxylase" P09172 9 133636363-133659329 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 272.7;brain: 236.6" "Cell type enriched" "Detected in some" 6 "Hepatic stellate cells: 10.0" "Cancer enhanced" "Detected in some" "liver cancer: 1.7" "Region enriched" "Detected in many" 8 "pons: 236.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 346 "SH-SY5Y: 1826.4" "Region enriched" "Detected in some" 6 "pons and medulla: 22.1" "Region enriched" "Detected in single" 26 "pons: 18.5" "HPA002130, HPA005960, HPA070789" Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA 1600000000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" Vesicles "Endoplasmic reticulum" "HPA002130: AB_2666554, HPA005960: AB_1078628, HPA070789: AB_2686312" "unprognostic (1.93e-3)" "unprognostic (7.52e-3)" "unprognostic (8.53e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-3)" "unprognostic (3.38e-3)" "unprognostic (3.39e-3)" "unprognostic (3.97e-2)" "unprognostic (1.71e-1)" "unprognostic (8.99e-2)" "unprognostic (5.80e-2)" "unprognostic (7.69e-2)" "unprognostic (2.81e-7)" "unprognostic (9.31e-2)" "unprognostic (6.77e-2)" "unprognostic (1.49e-2)" "unprognostic (5.06e-3)" 2.8 272.7 0.1 1.0 0.2 0.2 0.1 0.0 0.8 0.4 0.0 0.1 0.4 0.3 0.2 0.1 0.3 0.3 0.5 0.3 0.2 1.3 36.1 0.8 2.3 9.8 29.4 0.4 4.3 0.0 1.4 1.4 236.6 0.4 0.0 0.1 0.6 0.2 0.1 0.2 0.6 0.0 0.0 0.9 0.4 0.2 0.6 0.2 0.4 0.0 0.0 0.4 1.1 1.0 0.0 0.0 0.1 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 3.2 0.9 0.1 0.0 0.0 0.3 5.2 4.7 0.0 0.0 2.1 1826.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.8 0.3 0.2 9.8 29.4 236.6 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 DBNDD2 "C20orf35, HSMNP1" ENSG00000244274 "Dysbindin domain containing 2" Q9BQY9 20 45406057-45410610 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1300.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 18.8;Gastric mucus-secreting cells: 20.4;Macrophages: 10.7;Smooth muscle cells: 23.6;Squamous epithelial cells: 32.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 15 "dendritic cells: 18.7;monocytes: 12.5;T-cells: 9.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043991 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA043991: AB_10966212" "unprognostic (6.33e-2)" "unprognostic (1.68e-2)" "unprognostic (1.05e-1)" "unprognostic (2.79e-3)" "unprognostic (2.45e-1)" "unprognostic (1.62e-1)" "unprognostic (1.31e-3)" "unprognostic (8.24e-2)" "unprognostic (5.44e-2)" "unprognostic (3.06e-1)" "unprognostic (3.71e-2)" "unprognostic (2.47e-1)" "unprognostic (1.41e-3)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (2.52e-2)" "unprognostic (3.48e-1)" 71.5 29.7 627.6 33.6 916.1 7.1 59.4 827.6 1054.5 73.6 462.6 160.9 54.5 106.6 41.7 58.7 102.7 33.1 470.5 645.7 709.8 56.3 10.4 63.1 21.3 871.6 808.2 39.1 39.9 65.3 41.3 42.9 853.0 70.2 91.1 34.9 47.7 89.4 316.2 68.6 78.4 100.9 739.9 30.3 82.2 14.4 822.1 23.2 37.2 248.2 27.3 118.7 69.7 1300.9 78.0 13.6 10.8 76.3 6.8 3.0 15.0 44.7 48.4 36.7 24.8 37.2 103.4 1.1 7.7 44.4 13.9 112.1 74.7 4.0 22.4 0.6 43.9 64.5 57.0 34.3 43.1 3.5 94.0 1.2 12.6 13.9 12.8 63.5 25.3 64.8 4.7 1.5 2.9 99.0 5.6 4.9 14.0 50.8 80.0 0.3 1.0 0.7 105.3 1.4 24.8 12.7 15.6 8.4 99.3 7.6 104.0 19.9 41.1 1.5 72.5 48.8 49.5 1.1 1.6 0.3 5.3 0.6 10.9 0.0 10.4 0.0 9.1 12.5 3.3 0.2 8.0 6.8 7.6 0.3 7.4 6.9 0.5 0.8 7.2 18.7 7.4 4.5 627.6 916.1 827.6 1054.5 645.7 709.8 871.6 808.2 853.0 739.9 822.1 1300.9 0.3 3.2 0.5 0.0 3.3 0.0 0.2 0.1 18.8 0.0 0.6 0.3 1.0 0.0 2.5 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.3 0.4 0.2 2.7 0.0 2.1 0.0 0.0 0.0 7.3 20.4 0.4 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 10.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.5 0.0 3.9 0.4 0.9 0.0 5.3 0.0 0.0 0.6 23.6 0.1 0.0 32.7 0.6 0.0 5.3 0.1 0.4 0.3 DBNL "ABP1, HIP-55, SH3P7" ENSG00000136279 "Drebrin like" Q9UJU6 7 44044640-44069456 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Endocytosis, Immunity, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 338.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020265, HPA027735" Enhanced Supported "Vesicles,Plasma membrane" NA NA 3500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Plasma membrane" "HPA020265: AB_1850723, HPA027735: AB_10603790" "unprognostic (9.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (2.25e-1)" "unprognostic (6.18e-3)" "unprognostic (1.83e-1)" "unprognostic (5.88e-2)" "unprognostic (8.92e-2)" "unprognostic (5.76e-3)" "unprognostic (5.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-1)" "unprognostic (1.46e-1)" "unprognostic (9.51e-2)" 58.1 51.6 44.2 62.8 45.1 76.6 51.3 41.7 50.4 72.4 39.9 54.6 34.7 56.0 20.2 189.0 47.8 47.2 49.2 45.8 45.2 50.7 51.1 57.8 99.6 46.2 44.8 38.0 44.3 38.4 47.8 34.9 48.4 57.0 30.6 9.4 57.5 38.0 34.3 59.9 64.7 44.8 44.3 119.5 54.7 20.8 44.6 64.8 47.6 16.4 89.1 60.3 92.0 43.4 57.6 89.1 60.5 56.6 77.0 49.7 46.0 95.9 93.6 111.5 91.5 90.0 82.5 132.3 70.0 126.1 133.6 101.9 35.6 130.6 40.7 70.6 38.9 51.9 73.8 52.4 78.5 75.8 70.3 46.6 53.3 107.1 35.2 71.5 74.1 83.9 63.8 49.3 105.5 91.5 136.5 85.3 43.1 72.9 73.0 69.4 48.1 64.5 69.8 90.5 65.6 89.8 69.6 121.5 24.4 43.8 94.0 99.4 121.1 82.7 75.5 49.5 113.6 102.7 49.4 81.2 78.3 83.2 183.8 263.3 377.1 295.0 190.3 422.7 148.3 253.9 138.0 155.0 362.5 261.7 136.5 145.1 357.4 192.4 437.9 376.6 183.1 558.8 44.2 45.1 41.7 50.4 45.8 45.2 46.2 44.8 48.4 44.3 44.6 43.4 49.9 44.8 36.2 10.7 105.4 17.6 34.1 62.9 19.4 33.0 26.7 24.0 30.6 25.8 42.2 31.3 35.5 78.9 101.6 58.5 45.0 87.0 10.3 30.7 39.3 44.8 37.8 45.8 7.4 73.2 146.4 39.3 54.6 50.7 65.9 42.3 32.5 22.5 176.0 40.4 6.7 50.0 38.7 129.6 48.6 10.6 37.0 113.4 55.2 7.5 338.3 42.5 112.3 5.5 11.4 105.9 74.0 33.8 50.2 31.5 49.0 33.6 21.6 38.6 6.6 29.0 54.6 24.4 12.8 64.4 26.7 87.3 69.5 51.9 44.0 51.1 DBX1 ENSG00000109851 "Developing brain homeobox 1" A6NMT0 11 20156155-20160475 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "NTERA-2: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA039802 Uncertain NA NA "Cluster 5: NTERA-2 - Transcription" "HPA039802: AB_10795256" "unprognostic (3.76e-1)" "unprognostic (5.64e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DCAF15 "C19orf72, MGC99481" ENSG00000132017 "DDB1 and CUL4 associated factor 15" Q66K64 19 13952492-13961449 "Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068351 Approved Vesicles,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Mitochondria Vesicles "HPA068351: AB_2685977" "unprognostic (6.91e-2)" "unprognostic (6.55e-3)" "unprognostic (3.03e-2)" "unprognostic (5.18e-3)" "unprognostic (1.95e-1)" "unprognostic (1.89e-2)" "unprognostic (1.83e-3)" "unprognostic (9.72e-2)" "unprognostic (8.03e-2)" "unprognostic (1.21e-1)" "prognostic favorable (7.97e-4)" "unprognostic (1.98e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (7.97e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" 17.6 10.7 5.9 10.3 6.0 20.5 18.1 7.1 7.9 18.7 4.7 18.1 6.9 17.0 4.3 24.0 16.7 4.5 18.6 6.0 5.6 16.2 13.9 18.6 13.5 5.6 5.2 15.5 13.7 7.1 16.5 7.3 5.2 17.0 5.2 3.6 16.1 5.3 22.9 30.2 23.4 5.1 4.9 33.4 14.0 44.7 5.6 14.6 17.0 8.6 10.8 15.6 21.6 5.4 18.9 11.5 29.5 16.2 3.1 4.5 13.5 12.7 8.8 26.1 25.9 20.4 7.9 17.3 14.4 12.3 15.4 16.7 18.9 12.0 9.2 21.0 33.8 21.3 21.0 21.4 6.5 17.8 30.2 5.9 10.9 19.3 8.6 9.4 13.1 27.4 22.9 24.8 11.6 28.7 32.0 33.0 35.2 12.7 17.8 29.2 10.4 11.8 14.1 14.3 18.8 19.3 11.4 8.1 10.7 12.1 10.5 22.7 9.2 17.8 13.1 28.3 24.1 17.4 20.7 18.3 11.4 25.8 15.6 0.2 0.3 0.9 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.4 0.1 0.3 0.6 0.1 0.2 0.4 0.6 0.2 5.9 6.0 7.1 7.9 6.0 5.6 5.6 5.2 5.2 4.9 5.6 5.4 19.5 0.0 0.0 6.8 19.7 4.8 10.5 6.9 8.6 17.3 8.9 10.7 2.9 10.0 3.8 9.2 8.4 13.7 24.4 9.6 1.9 11.0 5.0 7.0 7.8 10.9 7.7 9.4 5.2 10.3 15.1 7.5 13.7 7.0 1.3 15.0 7.1 3.4 15.7 15.2 3.4 5.7 4.1 8.1 7.0 9.5 18.3 14.3 1.8 8.4 13.8 9.2 16.5 7.1 5.5 9.9 9.6 12.0 18.3 6.4 4.5 4.7 3.9 13.9 6.6 6.0 7.9 35.6 19.9 10.0 9.8 13.8 21.2 10.4 7.9 8.9 DCD "AIDD, DCD-1, DSEP, HCAP, PIF" ENSG00000161634 Dermcidin P81605 12 54644589-54648493 "Plasma proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 2476.8" "Cell type enriched" "Detected in some" 355 "Melanocytes: 8167.8" "Cancer enriched" "Detected in some" 9 "breast cancer: 91.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "Karpas-707: 1.0" HPA063967 Enhanced "Secreted in other tissues" NA NA 410000000 "Cluster 42: Non-specific - Transcription" "Cluster 61: Skin - Cornification" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA063967: AB_2685163" "unprognostic (3.55e-2)" "unprognostic (1.61e-1)" 100.2 0.4 3.5 0.3 3.3 1.1 354.3 3.4 5.4 0.3 3.8 0.7 0.2 0.7 0.9 0.5 0.2 0.8 1.3 3.5 3.3 0.2 0.9 0.6 0.2 3.3 3.6 0.4 1.0 0.0 0.5 0.1 3.5 0.4 0.2 0.5 0.5 0.1 14.0 2476.8 0.7 0.1 3.0 0.4 0.7 1.1 3.2 0.3 0.5 0.0 0.2 0.2 0.7 4.1 0.2 0.3 0.4 0.4 0.3 0.4 0.4 0.5 0.1 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.4 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.5 0.2 0.0 0.2 0.1 0.3 0.2 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.1 1.9 0.4 0.5 0.4 0.3 0.6 0.5 0.4 0.3 0.2 0.4 0.5 0.5 1.1 0.9 0.7 0.5 0.6 0.2 3.5 3.3 3.4 5.4 3.5 3.3 3.3 3.6 3.5 3.0 3.2 4.1 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.1 0.0 0.0 8167.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.4 0.2 0.0 23.0 0.0 1.0 0.0 0.0 0.0 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DDIAS "C11orf82, FLJ25416, FLJ38838, noxin" ENSG00000165490 "DNA damage induced apoptosis suppressor" Q8IXT1 11 82899975-82958277 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;testis: 10.8" "Cell type enhanced" "Detected in many" "Plasma cells: 8.2;Spermatocytes: 17.2;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038540, HPA038541" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA038540: AB_10672648, HPA038541: AB_2676071" "unprognostic (2.53e-1)" "unprognostic (2.27e-1)" "unprognostic (5.04e-3)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "unprognostic (5.32e-2)" "unprognostic (3.86e-6)" "unprognostic (4.65e-3)" "unprognostic (1.01e-3)" "unprognostic (8.24e-3)" "unprognostic (2.04e-4)" "unprognostic (4.72e-2)" "unprognostic (1.11e-16)" "unprognostic (7.17e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-1)" "unprognostic (9.13e-2)" 0.9 0.4 0.6 3.3 0.9 7.9 2.1 0.9 1.0 0.7 0.4 1.8 1.6 1.2 1.0 2.9 0.5 0.7 0.5 0.8 0.4 0.4 1.2 3.4 4.4 0.8 0.8 0.5 0.9 0.1 0.1 1.9 0.7 0.5 2.2 0.5 0.8 0.4 1.0 2.2 1.5 1.8 0.5 2.9 0.9 10.8 0.8 5.3 0.4 0.9 6.2 3.5 0.9 1.8 13.6 22.6 21.0 15.2 1.9 3.1 15.3 25.4 10.5 26.8 31.0 22.4 16.2 16.1 36.1 5.7 21.6 24.7 36.0 15.5 36.8 30.7 19.7 23.1 10.6 9.1 0.2 28.6 19.7 0.7 1.4 33.8 15.6 2.3 12.8 20.5 23.9 27.0 23.9 19.6 27.0 23.2 25.1 36.5 24.4 20.0 40.5 20.6 5.7 23.3 15.6 21.5 15.2 15.6 5.7 20.2 16.5 11.7 6.0 26.7 35.9 71.1 30.4 15.4 44.3 56.4 8.4 20.2 26.3 0.7 10.3 4.1 0.5 7.9 0.2 1.1 0.3 0.7 4.5 1.7 0.6 0.4 5.5 2.2 8.5 1.4 0.5 3.2 0.6 0.9 0.9 1.0 0.8 0.4 0.8 0.8 0.7 0.5 0.8 1.8 0.3 0.0 0.0 0.0 4.3 0.0 0.6 0.0 1.8 0.0 1.1 1.1 0.9 1.5 0.0 0.0 0.0 2.7 1.0 0.6 0.0 0.9 4.2 1.0 0.6 0.8 0.0 6.5 0.6 0.6 5.5 0.8 1.1 1.2 0.0 2.5 0.7 0.7 2.5 0.0 0.3 0.7 0.0 6.4 0.0 1.9 0.3 3.5 0.0 1.9 4.5 0.0 4.1 0.5 0.6 0.5 0.1 0.7 8.2 0.7 0.3 0.3 0.0 0.0 0.0 0.8 1.1 17.2 18.2 5.4 0.0 0.3 1.5 0.5 1.6 0.9 DDOST "GATD6, KIAA0115, OST, OST48, WBP1" ENSG00000244038 "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit" P39656 1 20651767-20661544 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 350.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009746, HPA046841, HPA052867" Supported Supported "Endoplasmic reticulum" NA NA 120000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB009746: AB_2092075, HPA046841: AB_2679834, HPA052867: AB_2681977" "unprognostic (8.57e-3)" "unprognostic (1.35e-2)" "unprognostic (1.57e-2)" "prognostic favorable (5.99e-4)" "unprognostic (1.62e-1)" "prognostic unfavorable (4.88e-4)" "prognostic unfavorable (2.64e-5)" "unprognostic (1.33e-1)" "unprognostic (5.51e-3)" "unprognostic (2.70e-2)" "unprognostic (3.59e-2)" "unprognostic (3.72e-1)" "prognostic unfavorable (9.05e-7)" "unprognostic (1.07e-1)" "unprognostic (2.98e-1)" "unprognostic (1.69e-2)" "unprognostic (1.07e-1)" 98.1 132.7 44.6 108.5 46.4 191.4 111.9 44.9 46.3 130.7 64.1 161.4 119.4 115.8 224.5 113.2 137.4 98.2 123.4 47.2 53.7 100.6 137.2 104.4 104.6 48.1 45.3 139.5 259.8 112.7 119.1 183.3 46.9 99.8 165.7 42.1 151.7 130.4 80.0 87.3 108.4 122.8 46.1 113.1 139.0 83.4 52.4 84.0 185.6 66.4 121.6 119.3 92.8 51.4 366.0 206.7 178.8 533.9 347.4 359.8 376.6 286.1 545.9 435.5 445.3 278.9 678.8 275.8 501.8 447.0 238.7 292.7 250.4 334.3 321.3 257.0 256.3 235.7 138.5 375.0 513.2 377.5 618.8 371.6 370.2 365.2 439.5 522.8 504.1 180.5 116.3 445.0 266.5 251.1 179.6 308.2 196.5 529.8 214.2 164.5 238.6 492.2 358.7 150.4 133.0 238.3 294.0 299.1 413.5 257.1 237.8 566.8 260.2 249.7 279.6 435.1 274.6 586.1 677.5 195.6 409.4 489.4 342.0 272.0 268.3 257.3 255.6 284.2 270.3 230.4 218.1 239.9 389.7 207.8 203.1 209.6 63.8 266.1 251.4 320.1 256.0 490.6 44.6 46.4 44.9 46.3 47.2 53.7 48.1 45.3 46.9 46.1 52.4 51.4 62.0 35.3 72.3 7.5 93.6 50.2 95.8 200.6 47.3 18.3 70.0 62.5 22.1 77.2 120.0 35.0 29.2 350.7 92.9 52.5 39.2 162.5 29.9 44.7 71.9 65.2 71.8 49.6 10.9 148.3 270.0 102.8 74.5 71.6 79.1 113.2 55.3 74.4 140.8 16.8 9.4 152.6 79.3 66.8 78.8 13.9 74.6 74.5 85.4 6.5 96.4 54.1 87.6 15.6 10.7 93.5 89.7 60.9 320.5 68.9 69.1 54.3 78.9 24.6 46.0 42.5 103.3 136.0 171.3 55.1 53.6 349.7 78.5 122.9 133.7 84.3 DDR1 "CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6" ENSG00000204580 "Discoidin domain receptor tyrosine kinase 1" Q08345 6 30876421-30900156 "CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lactation, Pregnancy" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 90.9;HBEC3-KT: 70.1;RT4: 93.5;T-47d: 103.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010162, CAB025656, HPA057194" Approved Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" NA NA 4400000 "Cluster 30: Non-specific - Translation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cell Junctions" "CAB010162: AB_2092090, CAB025656: , HPA057194: " "unprognostic (2.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.75e-3)" "unprognostic (6.43e-2)" "unprognostic (1.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (4.41e-2)" "prognostic favorable (3.31e-10)" "unprognostic (1.42e-1)" "unprognostic (2.53e-1)" "unprognostic (5.49e-3)" "unprognostic (4.09e-2)" 26.5 50.4 24.1 5.3 49.5 0.4 54.6 47.9 20.2 55.2 4.8 57.7 12.3 23.4 4.5 150.1 46.2 11.4 42.1 17.5 40.7 96.8 6.3 33.7 1.2 68.7 47.3 41.5 99.7 19.7 67.9 4.2 57.9 70.2 10.7 4.5 131.7 13.8 40.5 121.1 47.3 1.1 38.8 11.5 71.1 16.5 46.3 7.0 85.9 4.3 3.0 45.0 88.4 58.9 58.2 18.5 26.0 5.4 1.7 2.4 16.2 1.4 0.4 0.8 0.1 25.2 29.8 0.5 30.9 5.1 26.8 90.9 5.7 70.1 0.3 32.0 9.9 0.2 18.7 6.7 5.0 0.0 1.2 3.3 35.4 0.4 0.5 16.1 2.0 1.4 17.3 0.7 4.0 36.5 2.0 0.1 4.5 31.8 3.8 3.9 19.5 2.2 13.1 93.5 4.7 2.5 5.4 41.4 19.4 8.6 103.0 0.6 4.3 12.8 11.7 1.2 13.6 0.8 0.1 2.6 8.4 0.0 11.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 24.1 49.5 47.9 20.2 17.5 40.7 68.7 47.3 57.9 38.8 46.3 58.9 1.9 35.3 24.6 54.5 3.8 53.0 68.3 125.5 67.2 7.4 77.0 57.9 18.0 37.1 79.8 90.1 0.0 63.6 1.5 109.7 5.9 125.5 15.1 58.5 6.5 4.1 46.2 2.7 1.2 76.2 26.0 7.4 63.7 58.4 1.3 29.5 2.2 0.6 6.1 6.7 7.5 69.8 109.9 0.8 5.4 30.1 8.4 2.5 16.0 9.4 13.1 139.9 1.0 60.3 73.8 71.5 78.2 5.3 0.8 68.1 77.3 5.4 104.2 8.0 6.6 10.5 11.9 1.5 6.8 81.8 51.9 46.5 1.9 4.1 67.1 88.4 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 DDX17 P72 ENSG00000100201 "DEAD-box helicase 17" Q92841 22 38483438-38507660 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, mRNA processing, mRNA splicing, RNA-mediated gene silencing, rRNA processing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024908, HPA063142" Supported Supported "Nuclear speckles" "Intracellular and membrane" NA NA 420000 "Cluster 1: Neutrophils - Mixed function" "Cluster 51: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "CAB024908: , HPA063142: AB_2684949" "unprognostic (1.46e-2)" "unprognostic (5.99e-3)" "unprognostic (4.24e-3)" "unprognostic (6.67e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-2)" "unprognostic (1.36e-2)" "prognostic favorable (6.06e-4)" "unprognostic (1.17e-1)" "unprognostic (5.51e-1)" "unprognostic (2.52e-2)" "unprognostic (2.73e-2)" "unprognostic (1.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.76e-1)" "unprognostic (4.31e-2)" "unprognostic (3.19e-3)" 181.2 172.4 142.0 124.3 160.1 74.5 198.5 150.9 178.4 248.7 174.8 233.8 107.8 216.1 255.3 150.4 248.1 121.1 168.7 143.5 152.1 247.2 152.8 202.2 186.4 152.8 149.4 298.8 214.0 144.7 309.9 158.8 155.3 234.4 114.2 342.0 188.4 123.3 184.8 197.0 227.2 119.7 146.8 293.0 192.1 91.1 148.2 215.2 300.0 106.6 158.2 204.4 201.5 196.5 122.0 79.9 237.6 141.8 148.2 166.0 120.7 104.3 85.9 118.3 121.2 89.0 100.5 225.8 65.8 119.5 82.9 133.2 212.5 127.9 145.9 202.5 142.1 140.4 175.8 133.5 153.4 192.9 170.8 122.3 183.7 86.8 142.9 211.7 153.3 109.6 139.7 255.3 116.0 75.6 128.7 164.0 148.0 172.1 51.6 218.0 122.9 137.1 141.2 132.6 134.1 75.3 155.0 125.9 161.2 180.5 110.0 148.4 140.8 125.7 77.6 80.0 79.3 203.7 130.3 183.4 156.7 123.1 154.2 6.7 8.1 9.5 7.6 7.9 8.9 9.0 7.1 7.3 7.0 7.2 5.7 6.8 16.6 5.1 8.7 10.5 9.1 6.0 142.0 160.1 150.9 178.4 143.5 152.1 152.8 149.4 155.3 146.8 148.2 196.5 252.6 214.7 325.5 483.8 241.9 223.6 206.1 129.3 158.2 448.3 300.7 195.3 147.2 180.1 223.5 283.3 352.3 127.6 297.5 172.8 33.2 111.7 44.4 280.0 293.4 250.4 236.1 177.1 198.9 90.2 99.9 207.5 216.1 234.2 200.7 505.3 233.8 205.3 113.9 321.4 242.1 191.6 146.5 200.6 194.8 49.1 323.7 197.7 154.7 253.9 235.1 223.4 304.9 334.3 553.3 104.7 153.1 278.7 213.1 193.5 154.8 89.8 270.8 559.4 289.3 260.5 213.6 136.4 74.2 120.4 279.9 139.4 218.6 293.7 147.0 255.3 DDX20 "DP103, GEMIN3" ENSG00000064703 "DEAD-box helicase 20" Q9UHI6 1 111754832-111775602 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 52.8" "Group enriched" "Detected in all" 5 "Early spermatids: 738.2;Late spermatids: 718.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005516, CAB015427" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear bodies" Cytosol "CAB015427: AB_629518, HPA005516: AB_1849612" "unprognostic (3.71e-2)" "unprognostic (5.25e-2)" "prognostic favorable (9.85e-5)" "unprognostic (8.73e-2)" "unprognostic (2.51e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (6.35e-6)" "unprognostic (1.17e-1)" "unprognostic (5.87e-2)" "unprognostic (7.46e-3)" "unprognostic (4.21e-1)" "unprognostic (5.22e-2)" "unprognostic (1.05e-3)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (4.23e-1)" "unprognostic (1.30e-2)" 4.6 3.6 0.8 1.3 0.7 2.3 4.3 0.4 0.9 4.2 0.3 3.9 0.5 4.8 0.9 3.3 4.5 1.6 3.6 0.8 0.7 3.0 2.6 3.2 3.0 0.7 0.8 4.3 3.6 2.5 1.9 2.4 0.5 3.0 1.9 0.8 3.3 2.5 8.8 3.6 4.3 2.8 0.5 4.8 3.8 52.8 0.6 3.7 3.2 1.8 4.2 4.0 3.3 1.3 7.0 3.8 7.1 7.3 4.7 5.0 7.0 3.3 9.1 16.3 18.6 5.8 4.5 17.7 5.2 6.4 3.9 5.8 13.5 9.4 18.2 7.3 9.2 7.4 3.2 3.0 4.6 8.4 6.1 3.0 10.4 9.2 12.2 2.4 12.8 7.2 10.8 5.9 12.0 6.5 11.8 0.9 14.1 5.2 8.5 11.3 12.7 5.3 4.8 5.2 11.7 9.5 6.7 7.0 12.7 5.7 7.0 8.5 3.5 7.9 8.2 13.2 8.6 1.2 5.3 12.3 7.5 8.1 18.5 14.9 6.2 6.0 8.2 5.6 10.7 9.3 9.1 8.4 6.8 9.1 10.6 8.6 3.4 9.1 6.6 3.5 10.0 6.9 0.8 0.7 0.4 0.9 0.8 0.7 0.7 0.8 0.5 0.5 0.6 1.3 8.5 12.8 9.4 6.8 13.0 10.8 9.7 6.0 9.6 14.3 6.5 6.6 7.7 5.7 10.0 5.5 2.1 10.2 9.4 2.9 3.9 9.5 738.2 8.1 12.0 9.3 4.2 5.9 7.4 6.9 7.5 6.9 5.1 5.4 7.6 12.3 5.7 5.9 9.3 6.7 7.7 5.8 8.2 7.2 7.0 718.9 16.4 7.3 1.8 3.7 7.5 6.9 6.2 3.0 3.6 6.3 2.3 13.2 9.0 5.2 3.0 7.6 11.8 10.4 6.6 9.7 11.7 121.7 26.3 7.0 7.2 5.1 11.1 14.0 6.6 5.5 DDX25 GRTH ENSG00000109832 "DEAD-box helicase 25" Q9UHL0 11 125903348-125943702 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Translation regulation, Transport" "Developmental protein, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 91.4" "Group enriched" "Detected in some" 4 "Early spermatids: 332.1;Spermatocytes: 266.3" "Cancer enhanced" "Detected in some" "glioma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "JURKAT: 16.1;NTERA-2: 10.8;SCLC-21H: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020137 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA020137: AB_1847552" "unprognostic (5.78e-3)" "unprognostic (9.75e-3)" "unprognostic (7.93e-2)" "unprognostic (5.09e-3)" "unprognostic (1.11e-2)" "unprognostic (1.78e-2)" "unprognostic (1.54e-1)" "unprognostic (2.91e-3)" "unprognostic (6.24e-5)" "unprognostic (2.57e-1)" "unprognostic (2.44e-3)" "unprognostic (3.89e-1)" "unprognostic (3.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.69e-1)" 0.4 2.7 15.0 0.1 16.1 0.3 0.3 12.4 17.0 0.3 4.0 0.4 0.4 0.3 0.2 0.1 0.6 0.1 0.0 14.3 16.7 2.6 0.3 0.2 0.1 8.7 10.4 0.6 1.4 1.7 14.9 0.2 10.6 0.2 0.1 21.8 0.2 0.4 0.1 1.1 0.1 0.0 7.6 0.3 0.4 91.4 15.0 0.6 4.7 0.1 0.1 0.0 0.2 13.5 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.2 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 16.1 0.0 0.2 0.0 0.5 1.7 0.0 10.8 0.5 0.0 0.4 0.0 0.0 0.0 0.1 8.7 1.9 0.1 0.0 1.7 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.6 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 15.0 16.1 12.4 17.0 14.3 16.7 8.7 10.4 10.6 7.6 15.0 13.5 0.2 0.0 0.5 16.0 0.5 0.1 0.8 0.0 2.2 18.0 0.1 0.8 1.1 0.0 0.0 0.0 16.7 0.1 0.0 0.0 3.9 0.3 332.1 0.2 0.0 1.0 0.0 0.0 18.0 0.2 0.2 0.4 0.0 0.1 0.0 2.3 0.4 0.5 0.1 16.8 23.1 0.0 0.0 0.0 0.3 66.0 3.7 0.4 0.0 1.9 0.0 20.2 0.0 15.6 3.1 0.1 0.0 4.9 0.0 0.5 0.0 2.7 0.0 16.6 0.0 0.2 0.3 266.3 28.6 0.4 0.0 0.0 0.1 4.0 0.0 0.2 DDX3X "DBX, DDX14, DDX3, HLP2" ENSG00000215301 "DEAD-box helicase 3 X-linked" O00571 X 41333348-41364472 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 887.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059585" Supported Supported Approved Nucleoplasm,Cytosol NA NA 260000 "Cluster 18: Basophils - Vesicular transport" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Cytosol Nucleoplasm "HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059585: AB_2684073" "unprognostic (2.42e-2)" "unprognostic (1.11e-1)" "unprognostic (8.01e-3)" "unprognostic (1.66e-1)" "unprognostic (8.12e-2)" "unprognostic (6.43e-2)" "unprognostic (1.17e-3)" "unprognostic (1.88e-1)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.25e-2)" "unprognostic (2.05e-1)" "unprognostic (1.51e-1)" "unprognostic (2.95e-1)" "unprognostic (4.77e-1)" "unprognostic (9.44e-2)" "unprognostic (2.93e-2)" 164.7 123.2 28.7 113.3 29.9 146.1 99.8 31.9 37.3 102.4 38.8 85.6 80.7 123.4 39.1 107.6 108.8 111.0 96.4 27.0 36.0 110.5 130.6 103.5 118.7 33.6 29.8 108.1 76.9 133.0 52.5 107.3 34.2 68.7 75.8 81.9 72.9 64.8 126.9 91.2 81.6 145.1 32.4 103.2 84.4 43.0 30.9 169.6 104.3 112.5 111.5 153.3 97.7 34.7 230.5 225.6 236.3 122.3 273.6 211.1 136.4 150.6 239.3 167.1 132.3 238.8 141.4 2.5 103.9 185.8 212.4 149.4 292.2 235.0 248.3 130.2 232.9 132.6 237.6 152.1 140.5 253.8 236.4 159.1 150.9 278.4 270.3 204.1 258.3 131.5 258.4 134.5 158.9 157.8 163.0 83.2 212.2 121.3 114.2 187.8 223.3 182.6 143.7 279.1 147.1 220.0 352.3 184.3 194.3 248.9 158.9 172.4 224.5 159.6 166.3 178.7 188.2 153.6 194.0 215.7 161.5 156.1 151.5 50.8 39.0 30.7 23.3 35.3 33.5 21.0 23.3 26.3 34.7 13.0 25.4 25.3 54.0 30.7 39.4 11.7 24.8 37.8 28.7 29.9 31.9 37.3 27.0 36.0 33.6 29.8 34.2 32.4 30.9 34.7 466.5 86.6 150.0 66.9 280.1 264.3 160.5 63.7 191.8 77.1 295.1 237.6 158.0 81.5 96.5 58.8 131.3 94.6 415.2 231.1 43.0 64.3 370.6 261.1 237.7 238.5 183.7 113.0 43.8 85.6 95.1 191.8 178.9 290.1 165.5 180.6 144.2 174.5 123.1 60.6 47.1 161.4 71.2 208.7 269.1 887.5 66.5 319.0 128.1 47.8 112.2 90.0 79.3 44.7 63.1 114.1 156.7 62.8 241.8 145.0 234.9 87.3 102.5 127.1 72.3 351.4 210.1 30.6 57.7 212.6 333.4 172.9 342.4 144.8 129.1 225.8 DEAF1 "NUDR, SPN, ZMYND5" ENSG00000177030 "DEAF1 transcription factor" O75398 11 644233-706715 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 67.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 108.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030302 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" "Intracellular and membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Nucleoli fibrillar center" "HPA030302: AB_2673421" "unprognostic (1.32e-2)" "unprognostic (3.32e-2)" "unprognostic (3.58e-3)" "unprognostic (5.90e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (2.42e-2)" "unprognostic (2.65e-1)" "unprognostic (2.48e-1)" "unprognostic (2.61e-3)" "unprognostic (2.43e-1)" "unprognostic (2.39e-2)" "unprognostic (2.79e-1)" "unprognostic (3.03e-1)" "unprognostic (1.20e-1)" "unprognostic (5.15e-2)" 10.9 19.7 51.5 6.5 50.6 9.2 12.5 30.6 67.1 13.2 15.3 12.1 7.8 13.3 10.0 19.8 14.6 9.4 11.0 60.8 32.5 15.4 8.0 9.1 8.7 32.4 36.0 12.4 16.2 11.3 16.9 6.9 32.9 14.6 4.1 4.5 21.4 7.2 16.6 17.5 10.1 8.0 24.5 11.1 20.0 15.0 40.2 9.7 25.3 13.9 6.3 10.7 12.8 45.9 14.1 13.6 22.9 13.1 18.4 22.8 13.5 14.1 18.2 28.3 20.6 9.7 18.6 5.4 14.8 14.0 9.0 14.4 18.1 12.9 4.3 24.2 108.1 13.5 8.5 13.0 32.8 28.0 22.3 20.4 18.1 5.1 15.4 20.1 22.4 15.5 29.0 28.8 11.3 10.9 11.7 31.9 49.9 20.3 24.0 28.1 6.8 24.2 21.9 3.0 27.3 31.8 10.4 18.2 12.9 5.8 8.4 9.7 26.6 10.5 4.7 4.5 13.7 24.5 9.3 10.2 13.4 21.2 22.9 0.0 2.0 2.3 1.6 1.3 1.7 0.6 3.4 1.7 2.8 0.4 3.9 2.0 0.8 2.0 1.2 0.1 1.4 1.1 51.5 50.6 30.6 67.1 60.8 32.5 32.4 36.0 32.9 24.5 40.2 45.9 20.1 0.0 3.9 12.7 8.7 13.3 27.1 11.8 11.4 20.0 35.8 25.7 8.2 18.6 8.0 35.0 10.4 14.9 12.3 10.0 52.8 19.5 3.6 19.6 15.0 19.3 10.9 25.0 33.8 11.1 6.4 20.1 10.7 26.2 0.0 40.1 10.8 12.4 10.0 60.6 35.2 9.3 12.2 12.9 10.2 6.5 19.9 11.2 17.8 17.8 13.7 39.9 7.2 19.1 17.4 15.4 10.6 30.1 9.0 36.0 16.9 34.2 10.0 19.9 13.1 11.4 16.8 7.5 22.1 17.3 15.5 15.5 12.4 42.2 9.1 32.4 DEF8 FLJ20186 ENSG00000140995 "Differentially expressed in FDCP 8 homolog" Q6ZN54 16 89948697-89968060 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041745, HPA049434" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cytosol" "HPA041745: AB_2677650, HPA049434: " "unprognostic (4.99e-2)" "unprognostic (1.01e-1)" "unprognostic (9.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.08e-1)" "unprognostic (8.24e-2)" "unprognostic (1.91e-3)" "unprognostic (9.96e-2)" "unprognostic (2.74e-1)" "unprognostic (1.39e-2)" "prognostic favorable (1.35e-7)" "unprognostic (1.39e-2)" "prognostic favorable (1.95e-8)" "unprognostic (9.05e-2)" "unprognostic (1.40e-1)" "unprognostic (2.32e-2)" "unprognostic (2.09e-1)" 37.0 40.3 58.3 38.0 59.4 45.4 36.2 60.0 68.5 41.2 38.1 52.4 20.0 45.9 19.4 45.5 42.1 25.4 49.4 57.5 54.7 45.3 35.2 40.8 72.6 71.6 62.1 47.4 51.2 32.3 50.6 17.1 66.9 42.5 13.5 26.9 37.7 27.5 40.8 48.9 33.7 27.7 50.6 45.6 45.9 14.1 62.6 9.8 41.6 24.8 52.0 44.6 36.4 62.4 54.4 107.7 47.0 65.1 46.9 47.4 56.6 82.9 68.1 117.9 53.8 114.9 64.0 66.8 61.2 54.6 47.1 34.6 55.4 94.1 51.4 16.0 164.6 29.5 62.3 167.4 49.6 21.3 44.9 56.0 77.3 84.1 46.3 48.3 87.1 58.2 97.6 21.8 70.7 198.3 41.4 64.2 60.8 24.6 110.2 86.9 35.8 55.3 62.0 50.0 72.1 74.2 131.5 48.3 44.6 24.3 45.4 67.1 89.9 68.9 73.3 36.0 88.3 40.5 31.3 85.1 72.5 54.2 82.1 8.2 39.3 80.7 26.6 33.1 24.0 49.3 21.8 19.6 26.2 61.1 14.5 14.1 52.6 13.1 18.9 69.1 29.6 27.5 58.3 59.4 60.0 68.5 57.5 54.7 71.6 62.1 66.9 50.6 62.6 62.4 27.7 0.0 14.8 31.0 32.6 44.7 22.1 33.0 15.4 24.1 20.1 22.2 33.9 21.5 20.4 14.7 27.1 29.3 30.7 20.0 29.4 42.6 6.5 12.0 25.5 27.8 21.6 9.1 19.2 92.3 48.2 31.5 11.7 15.6 10.1 20.3 20.7 23.9 63.5 30.3 19.3 17.9 42.7 33.5 62.7 23.3 21.1 30.1 46.2 14.0 56.1 17.8 21.6 15.6 22.6 112.4 20.4 33.4 65.1 46.6 16.9 47.7 16.4 26.3 19.7 20.4 40.7 6.2 11.2 19.9 54.7 32.4 17.5 33.3 15.8 30.1 DEFA1 "DEF1, DEFA2, HNP-1, MRS" ENSG00000206047 "Defensin alpha 1" P59665 8 6977649-6980080 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 18020.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 18 "NB-4: 2.1" "CAB032548, HPA052517" Enhanced "Secreted to blood" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "CAB032548: AB_2277258, HPA052517: AB_2681860" 31.6 4.3 0.7 0.6 0.8 18020.9 16.8 0.5 3.0 4.0 0.6 4.1 0.0 11.3 0.0 3.2 2.2 1.3 62.5 0.5 0.6 15.0 91.6 560.5 3.5 0.7 0.7 4.1 5.5 0.1 20.6 11.4 0.7 2.7 0.0 0.3 14.5 0.0 16.8 40.3 2.3 0.0 0.8 1803.8 6.4 3.1 0.8 37.0 15.8 0.0 0.8 3.4 5.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.5 3.0 0.5 0.6 0.7 0.7 0.7 0.8 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 DEFA1B ENSG00000240247 "Defensin alpha 1B" P59665 8 6996766-6999195 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 872.0" "Cell type enriched" "Detected in single" 37 "T-cells: 3.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebral cortex: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052517 Supported "Secreted to blood" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA052517: AB_2681860" 2.3 0.3 0.1 0.8 0.1 872.0 1.1 0.1 2.0 0.0 0.1 0.2 0.0 0.9 0.0 0.1 0.1 0.0 3.8 0.2 0.1 0.9 9.1 52.1 0.0 0.2 0.1 0.3 0.1 0.0 1.4 7.2 0.4 0.1 0.0 0.1 9.4 0.0 0.8 0.2 0.2 0.0 0.1 150.4 0.6 0.1 0.4 27.8 1.2 5.8 1.4 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.0 0.2 0.1 0.2 0.1 0.4 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 DEFA3 "DEF3, HNP-3" ENSG00000239839 "Defensin alpha 3" P59666 8 7015869-7018297 "Cancer-related genes, Predicted secreted proteins" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 64 "bone marrow: 37615.2" "Cell type enhanced" "Detected in some" "B-cells: 17.9;Erythroid cells: 10.1;Hepatocytes: 17.0;Macrophages: 5.7;Plasma cells: 4.0;T-cells: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 19 "neutrophil: 854.3" "Lineage enriched" "Detected in many" 19 "granulocytes: 854.3" "Cell line enriched" "Detected in single" 8 "NB-4: 1.5" HPA052517 Supported "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "HPA052517: AB_2681860" "unprognostic (8.21e-2)" 8.8 1.2 0.5 1.0 0.3 37615.2 5.0 0.2 1.2 2.0 0.3 1.3 0.0 5.6 0.0 1.0 0.7 0.2 16.1 0.2 0.3 4.4 26.1 180.2 5.3 0.4 0.6 1.3 1.6 0.0 7.6 18.8 0.5 0.8 0.0 0.2 24.2 0.0 5.0 42.1 0.7 0.0 0.5 589.4 1.8 0.6 0.6 147.9 4.5 1.1 1.3 1.1 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 24.4 3.6 44.3 1.2 1.6 2.3 1.0 0.8 1.0 1.1 6.9 0.3 854.3 0.4 2.6 1.4 0.3 6033.6 0.5 0.3 0.2 1.2 0.2 0.3 0.4 0.6 0.5 0.5 0.6 0.2 0.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 10.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.8 17.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 DEFA4 "DEF4, HP-4" ENSG00000164821 "Defensin alpha 4" P12838 8 6935820-6938306 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "bone marrow: 2702.9" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Hepatocytes: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 13 "neutrophil: 13.1" "Lineage enriched" "Detected in many" 13 "granulocytes: 13.1" "Cell line enriched" "Detected in single" 8 "THP-1: 6.8" HPA051266 Enhanced "Secreted to blood" NA NA 98000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA051266: AB_2681414" 0.7 0.1 0.0 0.2 0.0 2702.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.3 2.7 14.2 0.6 0.0 0.0 0.0 0.1 0.0 0.7 1.1 0.0 0.0 0.0 0.0 2.3 0.0 0.4 2.0 0.1 0.0 0.0 46.4 0.1 0.1 0.0 8.9 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 DEFA5 "DEF5, HD-5" ENSG00000164816 "Defensin alpha 5" Q01523 8 7055304-7056739 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 768 "intestine: 9759.8" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 1740.2;Undifferentiated cells: 1753.0" "Cancer enhanced" "Detected in many" "cervical cancer: 181.1;colorectal cancer: 147.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BEWO: 28.3;NB-4: 24.2;RPMI-8226: 26.6;SH-SY5Y: 19.6;U-2197: 8.5" "HPA015309, HPA015775, CAB069919" Enhanced Approved Vesicles,Midbody "Secreted to digestive system" Yes NA 110000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles Midbody "CAB069919: AB_905358, HPA015309: , HPA015775: AB_1847594" "prognostic favorable (9.44e-5)" "unprognostic (3.91e-2)" 0.3 0.4 0.1 12.7 0.1 0.2 0.5 0.1 0.5 0.0 0.1 56.6 5185.1 3.9 0.1 0.8 0.0 0.0 0.4 0.1 0.2 0.2 1.1 0.4 6.0 0.1 0.2 0.4 0.8 0.0 1.1 0.0 0.2 0.7 0.2 0.1 0.7 0.0 0.3 0.3 9759.8 0.1 0.1 0.4 0.9 0.8 0.2 0.4 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.2 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 2.5 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.5 0.1 0.2 0.1 0.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 325.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 399.9 0.0 0.0 0.0 1740.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.4 0.0 1753.0 0.0 DEFA6 "DEF6, HD-6" ENSG00000164822 "Defensin alpha 6" Q01524 8 6924697-6926076 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 863 "intestine: 4819.9" "Group enriched" "Detected in some" 6 "Proximal enterocytes: 448.9;Undifferentiated cells: 904.1" "Group enriched" "Detected in many" 5 "cervical cancer: 21.2;colorectal cancer: 75.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BEWO: 14.7;NB-4: 15.9;RPMI-8226: 19.7;SH-SY5Y: 12.2;U-2197: 5.7" HPA019462 Enhanced "Secreted to digestive system" NA NA 260000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA019462: AB_1847595" "unprognostic (7.48e-3)" "unprognostic (1.63e-1)" "unprognostic (1.34e-1)" 0.1 0.2 0.0 5.5 0.0 0.3 0.2 0.0 0.0 0.0 0.0 25.7 2862.9 2.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.2 3.4 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.1 0.3 3.3 0.0 0.3 0.0 0.2 0.6 4819.9 0.0 0.0 0.2 0.4 0.6 0.0 2.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 1.1 12.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.6 0.0 0.0 0.0 0.5 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.4 0.0 0.0 0.0 448.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 904.1 0.0 DEFB1 "BD1, DEFB-1, DEFB101, HBD-1, HBD1, MGC51822" ENSG00000164825 "Defensin beta 1" P60022 8 6870592-6877936 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 1746.1;pancreas: 747.8;salivary gland: 1975.0" "Cell type enriched" "Detected in many" 6 "Distal tubular cells: 13300.4" "Cancer enhanced" "Detected in many" "renal cancer: 522.9" "Group enriched" "Detected in many" 4 "amygdala: 1.2;cerebellum: 1.5;hypothalamus: 1.0;midbrain: 2.4;thalamus: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 43.3" "Not detected" "Not detected" "Secreted in other tissues" NA NA 2500000 "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (2.31e-2)" "unprognostic (8.35e-3)" "unprognostic (1.24e-1)" "unprognostic (1.75e-1)" "unprognostic (1.89e-1)" "unprognostic (2.16e-3)" "unprognostic (4.41e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (2.77e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (5.94e-4)" "unprognostic (3.24e-1)" "prognostic favorable (1.90e-5)" "unprognostic (9.62e-2)" "unprognostic (2.86e-2)" "unprognostic (2.21e-2)" "unprognostic (1.16e-1)" 11.1 0.7 1.2 1.5 0.0 5.3 41.5 1.5 0.4 305.4 0.3 20.7 5.1 6.2 16.4 190.6 21.2 54.9 1.3 0.0 1.0 1746.1 248.4 5.7 0.0 0.0 2.4 0.5 747.8 6.9 12.7 2.1 0.2 37.9 11.5 1.9 1975.0 24.5 2.9 217.6 8.7 0.3 0.0 0.3 33.3 0.4 3.0 3.0 3.6 0.0 9.0 11.6 152.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.2 0.0 0.5 0.0 2.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 4.2 0.0 0.1 0.3 0.0 2.7 1.2 43.3 0.3 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.5 0.4 0.0 1.0 0.0 2.4 0.2 0.0 3.0 0.2 0.7 3.2 4.5 0.0 6.8 90.1 641.5 210.5 134.9 0.4 46.9 26.9 0.1 1976.0 57.2 982.1 0.0 11.8 0.4 117.6 13300.4 1860.0 0.0 339.5 223.6 8.8 15.7 0.0 0.0 295.4 0.9 19.0 1.5 1529.3 0.0 0.0 3.3 319.3 3.6 0.0 0.0 8.6 46.8 4.4 7.3 0.1 17.4 17.0 7.2 0.0 15.3 0.6 0.0 0.0 0.0 156.9 91.2 0.0 1.2 537.6 59.1 218.9 9.5 0.7 0.0 1.4 14.3 0.0 0.0 237.0 537.6 3.7 13.8 0.0 15.4 257.0 DEFB103A "DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3" ENSG00000176797 "Defensin beta 103A" P81534 8 7881392-7882663 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.6;salivary gland: 3.2;vagina: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 5.8;LHCN-M2: 1.7;U-2197: 3.0" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 7.6 0.0 3.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB103B ENSG00000177243 "Defensin beta 103B" P81534 8 7428888-7430348 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "cervix: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB104A "DEFB-4, DEFB104, DEFB4" ENSG00000176782 "Defensin beta 104A" Q8WTQ1 8 7836436-7841242 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 763 "epididymis: 1308.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045292 Supported "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA045292: AB_2679288" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1308.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB104B ENSG00000177023 "Defensin beta 104B" Q8WTQ1 8 7470308-7475082 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045292 Supported "Secreted in male reproductive system" NA NA "HPA045292: AB_2679288" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB105A "DEFB-5, DEFB105" ENSG00000186562 "Defensin beta 105A" Q8NG35 8 7821966-7823889 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB105B ENSG00000186599 "Defensin beta 105B" Q8NG35 8 7487679-7489593 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12966 "epididymis: 2383.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "NB-4: 4.2" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2383.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB106A "DEFB-6, DEFB106" ENSG00000186579 "Defensin beta 106A" Q8N104 8 7825139-7829053 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16935 "epididymis: 3003.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 18 "NB-4: 2.2" HPA045592 Supported "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "HPA045592: AB_2679378" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3003.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB106B ENSG00000187082 "Defensin beta 106B" Q8N104 8 7482504-7486400 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 685 "epididymis: 68.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045592 Supported "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA045592: AB_2679378" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB107A "DEFB-7, DEFB107" ENSG00000186572 "Defensin beta 107A" Q8IZN7 8 7811720-7815716 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 1392 "epididymis: 139.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045626 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA045626: AB_2679396" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB107B HsT21816 ENSG00000198129 "Defensin beta 107B" Q8IZN7 8 7495911-7509311 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5377 "epididymis: 537.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045626 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA045626: AB_2679396" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 537.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB108B ENSG00000184276 "Defensin beta 108B" Q8NET1 11 71833200-71837710 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 86 "epididymis: 12.8" "Cell type enriched" "Detected in single" 18 "Collecting duct cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 67: Proximal tubular cells - Tubular reabsorption" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB110 "DEFB-10, DEFB-11, DEFB111" ENSG00000203970 "Defensin beta 110" Q30KQ9 6 50009138-50021994 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4674 "epididymis: 871.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "NB-4: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 871.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB112 DEFB-12 ENSG00000180872 "Defensin beta 112" 6 50042099-50049929 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 56 "epididymis: 24.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB113 DEFB-13 ENSG00000214642 "Defensin beta 113" Q30KQ7 6 49968677-49969625 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 465 "epididymis: 46.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB115 DEFB-15 ENSG00000215547 "Defensin beta 115" Q30KQ5 20 31257664-31259632 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "epididymis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "U-2 OS: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA053160 Uncertain "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 9: U-2 OS - Unknown function" "HPA053160: AB_2682062" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB116 DEFB-16 ENSG00000215545 "Defensin beta 116" Q30KQ4 20 31303212-31308585 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047430 Uncertain "Secreted in male reproductive system" NA NA "HPA047430: AB_10964749" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB118 "C20orf63, DEFB-18, dJ1018D12.3, ESC42" ENSG00000131068 "Defensin beta 118" Q96PH6 20 31368601-31373923 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9912 "epididymis: 991.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.0" "Not detected" "Not detected" HPA042634 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA042634: AB_10797505" "unprognostic (3.24e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 991.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB119 "DEFB-19, DEFB-20, DEFB120" ENSG00000180483 "Defensin beta 119" Q8N690 20 31377164-31390590 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "epididymis: 1925.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 42.6;Cone photoreceptor cells: 39.6;Early spermatids: 61.9;Late spermatids: 99.8;Rod photoreceptor cells: 150.2" "Cancer enriched" "Detected in single" 67 "testis cancer: 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.5" HPA043059 Supported "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA043059: AB_10797025" "unprognostic (2.03e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.1 1925.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 155.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 331.5 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.6 0.0 0.0 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 61.9 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.1 0.0 0.0 0.0 0.0 99.8 12.5 0.8 0.0 0.0 0.0 22.0 0.0 0.0 0.1 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 150.2 13.1 0.0 0.0 17.4 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB121 DEFB-21 ENSG00000204548 "Defensin beta 121" Q5J5C9 20 31404845-31412838 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11866 "epididymis: 2605.3" "Group enriched" "Detected in some" 22 "Early spermatids: 14.5;Late spermatids: 5.4;Spermatocytes: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "NB-4: 3.1" "Not detected" "Not detected" HPA079460 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA079460: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2605.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB123 DEFB-23 ENSG00000180424 "Defensin beta 123" Q8N688 20 31440632-31450257 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 370 "epididymis: 158.8;testis: 148.1" "Group enriched" "Detected in some" 4 "Early spermatids: 14.0;Late spermatids: 50.4" "Cancer enriched" "Detected in single" 17 "testis cancer: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (9.16e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 158.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 148.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 50.4 5.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 5.2 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB124 DEFB-24 ENSG00000180383 "Defensin beta 124" Q8NES8 20 31465506-31476757 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 5.9;testis: 7.1" "Cell type enhanced" "Detected in some" "Club cells: 1.3;Endometrial stromal cells: 6.4;Respiratory ciliated cells: 4.0;Smooth muscle cells: 2.1" "Cancer enriched" "Detected in some" 4 "testis cancer: 2.9" "Region enriched" "Detected in single" 6 "cerebral cortex: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 2.7;HMC-1: 1.5;U-2 OS: 1.1;WM-115: 5.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (1.24e-2)" "unprognostic (9.76e-3)" "unprognostic (1.27e-1)" "unprognostic (3.23e-3)" "unprognostic (6.92e-3)" "unprognostic (3.69e-2)" "unprognostic (3.37e-2)" "unprognostic (1.78e-1)" "unprognostic (9.07e-2)" "unprognostic (4.43e-1)" "unprognostic (3.32e-7)" "unprognostic (1.56e-2)" "unprognostic (1.29e-1)" "unprognostic (4.42e-2)" "unprognostic (4.28e-1)" 3.1 0.4 0.2 0.2 0.1 0.0 1.7 0.1 1.5 3.7 1.7 2.1 0.0 3.2 2.7 0.6 5.9 0.0 0.9 0.2 0.2 0.4 0.1 0.7 0.5 0.2 0.2 0.6 0.2 0.8 0.9 0.1 0.2 1.2 0.6 0.0 0.6 3.0 1.0 0.4 0.9 0.5 0.1 0.8 0.7 7.1 0.1 0.2 1.0 0.8 0.5 1.4 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 1.5 0.2 0.2 0.2 0.2 0.2 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 6.4 0.2 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 2.1 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DEFB125 DEFB-25 ENSG00000178591 "Defensin beta 125" Q8N687 20 87250-97094 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "epididymis: 1.5;seminal vesicle: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB126 "bA530N10.1, C20orf8, DEFB-26" ENSG00000125788 "Defensin beta 126" Q9BYW3 20 142590-145751 "Disease related genes, Predicted secreted proteins" Fertilization "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 297 "epididymis: 1285.4" "Cell type enhanced" "Detected in single" "Prostatic glandular cells: 1.4" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.0;OE19: 3.4" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.16e-1)" "unprognostic (1.21e-1)" "unprognostic (3.16e-2)" "unprognostic (2.41e-2)" "unprognostic (2.32e-1)" "unprognostic (1.47e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1285.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 3.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.6 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.1 0.1 DEFB127 "bA530N10.2, C20orf73, DEF-27" ENSG00000088782 "Defensin beta 127" Q9H1M4 20 157454-159163 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1158 "epididymis: 1077.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1077.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB128 DEFB-28 ENSG00000185982 "Defensin beta 128" Q7Z7B8 20 187853-189711 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11940 "epididymis: 1193.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1193.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB129 "bA530N10.3, C20orf87, DEFB-29" ENSG00000125903 "Defensin beta 129" Q9H1M3 20 227258-229886 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 585 "epididymis: 1943.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 2.6;SH-SY5Y: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA014581 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "HPA014581: AB_2732410" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1943.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB130A "DEFB-30, DEFB130, DEFB30" ENSG00000232948 "Defensin beta 130A" P0DP74 8 12310962-12318316 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 26 "epididymis: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB130B ENSG00000233050 "Defensin beta 130B" P0DP73 8 12064389-12071747 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 26 "epididymis: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB131A "DEFB-31, DEFB131" ENSG00000186146 "Defensin beta 131A" P59861 4 9444534-9450514 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "epididymis: 167.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "thyroid cancer: 1.3" "Group enriched" "Detected in some" 4 "medulla oblongata: 1.2;pons: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "TIME: 2.1" "Secreted in other tissues" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "unprognostic (2.11e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 14.9 0.0 167.4 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 14.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 1.2 0.2 1.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB131B ENSG00000225805 "Defensin beta 131B" A0A096LNP1 11 71878453-71884561 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "epididymis: 68.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 15.6" "Secreted in male reproductive system" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "unprognostic (5.87e-2)" "unprognostic (1.44e-1)" "unprognostic (4.78e-2)" "unprognostic (7.44e-2)" "unprognostic (3.57e-2)" "unprognostic (3.55e-2)" "unprognostic (3.11e-3)" "unprognostic (1.91e-1)" "unprognostic (3.09e-3)" "unprognostic (7.45e-2)" "unprognostic (1.41e-1)" "unprognostic (1.43e-1)" "unprognostic (5.21e-2)" "unprognostic (3.39e-1)" "unprognostic (1.05e-2)" "unprognostic (3.62e-1)" 0.2 0.6 0.7 1.1 0.5 0.4 0.0 0.7 1.3 0.0 0.0 0.7 1.8 0.4 68.9 0.1 0.0 2.5 0.4 0.4 0.2 0.5 0.0 0.2 1.8 0.5 0.5 1.2 0.0 0.0 0.0 0.2 1.7 0.4 0.0 3.6 0.7 0.1 0.4 0.8 1.0 0.0 0.2 0.7 0.6 0.8 0.7 0.0 3.2 0.0 0.0 1.0 0.0 1.3 0.5 0.0 3.1 1.4 0.0 0.0 0.4 3.6 0.0 0.0 0.0 4.4 2.8 3.0 1.1 0.0 1.5 3.4 0.0 0.0 0.0 2.8 2.8 3.8 0.0 2.5 0.0 4.8 1.6 0.0 0.0 0.0 0.0 1.1 0.0 6.2 7.3 5.9 0.0 3.2 2.1 0.9 0.5 3.7 3.7 3.0 15.6 1.0 0.0 1.1 2.9 1.6 2.5 1.4 2.6 2.5 3.0 0.4 2.1 1.2 3.4 2.0 0.3 2.5 1.1 4.4 2.0 2.8 0.8 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.7 0.2 0.0 0.7 0.5 0.7 1.3 0.4 0.2 0.5 0.5 1.7 0.2 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB132 "DEFB32, RP5-1103G7.6" ENSG00000186458 "Defensin beta 132" Q7Z7B7 20 257724-261096 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "epididymis: 271.2" "Cell type enriched" "Detected in some" 7 "Collecting duct cells: 11.0" "Group enriched" "Detected in some" 4 "liver cancer: 0.8;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046399 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA046399: AB_10960992" "unprognostic (9.27e-3)" "unprognostic (1.61e-2)" "unprognostic (2.54e-2)" 25.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 271.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 1.5 0.0 11.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 DEFB133 ENSG00000214643 "Defensin beta 133" Q30KQ1 6 49946021-49950265 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 130 "epididymis: 12.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB134 ENSG00000205882 "Defensin beta 134" Q4QY38 8 11993174-11996312 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "epididymis: 13.0" "Group enriched" "Detected in some" 21 "Early spermatids: 48.3;Late spermatids: 33.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (3.80e-2)" "unprognostic (2.20e-1)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.2 0.0 13.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.1 0.3 0.0 0.1 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB135 ENSG00000205883 "Defensin beta 135" Q30KP9 8 11982321-11984590 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 50 "epididymis: 34.8" "Group enriched" "Detected in some" 9 "Early spermatids: 2.8;Late spermatids: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 2.2" "Region enhanced" "Detected in single" "white matter: 1.5" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.6 0.0 0.5 0.0 0.0 0.0 34.8 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.6 0.3 0.3 0.3 0.2 0.2 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB136 DEFB137 ENSG00000205884 "Defensin beta 136" Q30KP8 8 11973937-11974599 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "epididymis: 1.2" "Cell type enhanced" "Detected in single" "Late spermatids: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA068255 Enhanced "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 34: Spermatids - Unknown function" "HPA068255: AB_2732780" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB4A "DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1" ENSG00000171711 "Defensin beta 4A" O15263 8 7894677-7896716 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 124.1" "Group enriched" "Detected in some" 8 "Basal respiratory cells: 79.5;Club cells: 38.3;Exocrine glandular cells: 37.4;Pancreatic endocrine cells: 41.0" "Group enriched" "Detected in many" 6 "head and neck cancer: 32.2;melanoma: 9.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "EFO-21: 1.4" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (6.96e-2)" "unprognostic (1.17e-2)" "unprognostic (2.72e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (2.75e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 124.1 0.1 3.6 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.0 0.0 3.2 0.4 0.0 0.0 0.0 7.3 0.0 0.0 5.0 0.0 0.0 7.6 0.2 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.5 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.1 0.0 5.6 0.0 4.3 0.0 5.3 0.2 0.0 0.0 0.0 0.0 37.4 0.0 0.0 3.1 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.0 1.1 0.0 0.0 0.1 0.0 0.1 3.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 DEFB4B DEFB4P ENSG00000177257 "Defensin beta 4B" O15263 8 7414855-7416863 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 12.0;lymphoid tissue: 3.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (1.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DENND3 KIAA0870 ENSG00000105339 "DENN domain containing 3" A2RUS2 8 141117278-141195808 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.0;Microglial cells: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 34.6;neutrophil: 39.8" "Group enriched" "Detected in many" 5 "granulocytes: 39.8;monocytes: 10.0" "Cell line enhanced" "Detected in many" "HDLM-2: 64.6;HeLa: 89.5;U-937: 58.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024491, HPA041668" Approved Approved Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "HPA024491: AB_2671581, HPA041668: " "unprognostic (2.27e-1)" "unprognostic (9.62e-2)" "unprognostic (9.47e-3)" "unprognostic (1.66e-1)" "unprognostic (6.96e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (7.07e-3)" "unprognostic (2.71e-2)" "unprognostic (2.25e-2)" "unprognostic (7.74e-2)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (4.51e-2)" "unprognostic (5.42e-2)" 42.8 8.9 21.7 27.2 18.8 106.4 28.2 12.2 28.4 22.9 14.7 36.2 5.7 17.8 2.1 7.5 19.1 13.6 24.9 19.9 17.7 21.5 6.5 57.9 28.6 33.6 24.7 15.1 7.6 4.1 10.0 15.1 25.7 16.9 7.8 3.7 18.2 8.5 13.8 15.6 23.7 8.3 22.7 43.9 15.8 6.1 21.2 7.1 20.6 11.7 25.1 12.4 17.6 31.4 16.4 14.8 1.0 3.1 4.4 6.4 2.4 8.5 27.4 3.8 3.0 4.6 15.3 4.2 22.8 17.5 7.5 7.8 4.2 10.0 2.7 64.6 3.6 17.3 89.5 1.4 3.9 17.2 2.4 0.5 5.1 4.2 5.3 9.2 21.1 7.8 0.2 40.7 2.9 5.2 2.6 24.1 1.1 3.2 16.6 2.9 0.8 16.6 14.8 5.6 4.7 3.0 1.8 1.3 1.1 7.3 6.8 27.6 16.7 0.7 6.8 10.6 0.3 8.0 37.0 1.3 2.6 58.6 1.0 24.3 5.4 34.6 0.8 8.0 0.8 5.0 0.6 0.3 4.1 4.3 0.1 0.2 39.8 2.7 10.0 0.1 0.2 3.5 21.7 18.8 12.2 28.4 19.9 17.7 33.6 24.7 25.7 22.7 21.2 31.4 49.0 157.0 35.2 2.6 39.7 15.7 7.6 11.7 7.4 4.5 6.3 2.0 10.1 10.0 18.8 22.0 4.2 0.7 29.5 18.3 1.9 3.5 6.1 15.1 8.1 31.7 4.8 5.7 53.9 3.5 0.6 4.8 16.8 14.5 10.8 1.9 16.4 0.3 24.4 1.7 5.2 7.9 4.1 55.6 22.2 2.8 1.5 39.7 8.8 79.6 33.0 0.7 21.6 1.5 1.1 11.0 9.9 0.7 38.8 20.3 1.5 2.7 15.1 0.5 39.5 2.1 21.5 8.7 8.5 2.9 9.1 0.5 12.5 0.6 4.1 6.3 DENND5A "FLJ22354, FLJ33829, FLJ43455, KIAA1091, RAB6IP1" ENSG00000184014 "DENN domain containing 5A" Q6IQ26 11 9138825-9265959 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 287.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052923, HPA055009" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Vesicles" "HPA052923: AB_2681989, HPA055009: AB_2682669" "unprognostic (5.28e-3)" "unprognostic (1.42e-1)" "unprognostic (1.17e-1)" "unprognostic (1.28e-2)" "unprognostic (4.03e-1)" "unprognostic (3.48e-1)" "prognostic unfavorable (5.05e-6)" "unprognostic (1.84e-1)" "unprognostic (2.96e-1)" "unprognostic (1.02e-1)" "unprognostic (5.15e-2)" "unprognostic (3.10e-1)" "prognostic unfavorable (1.14e-6)" "unprognostic (9.86e-3)" "unprognostic (1.03e-1)" "unprognostic (4.32e-1)" "unprognostic (1.40e-2)" 45.8 23.5 72.4 23.2 90.5 21.7 36.3 85.0 80.7 36.1 45.5 44.2 5.8 38.5 14.1 17.4 37.5 23.3 58.0 65.1 85.4 25.5 15.7 46.1 16.8 81.5 86.6 30.2 23.2 18.5 20.5 28.8 77.0 24.5 12.9 34.7 19.5 40.0 26.7 17.3 20.2 47.5 74.9 31.4 23.7 15.8 87.3 28.0 22.0 33.7 15.9 40.4 25.1 81.3 18.8 23.3 63.7 56.1 113.0 92.0 61.7 69.2 99.8 85.7 104.5 16.4 13.6 0.0 30.5 129.0 82.4 12.7 64.3 22.5 111.4 73.0 30.9 6.2 32.2 34.5 61.0 34.4 13.9 76.8 11.5 51.1 74.6 59.7 83.8 21.9 33.6 0.3 101.9 11.0 19.4 15.1 19.7 3.2 28.6 34.2 46.1 0.3 41.6 13.4 15.9 32.1 65.8 29.7 27.2 70.4 15.7 24.6 59.2 63.0 41.0 78.7 47.3 1.4 0.4 18.7 63.4 14.1 51.9 4.4 5.0 5.7 0.1 6.3 0.6 1.8 1.3 1.3 4.6 0.2 3.8 1.9 10.8 1.0 9.2 1.1 0.0 1.9 72.4 90.5 85.0 80.7 65.1 85.4 81.5 86.6 77.0 74.9 87.3 81.3 34.1 19.2 14.5 43.8 7.4 21.7 19.3 10.3 10.2 9.7 15.3 13.8 33.2 14.3 8.0 14.7 60.5 15.9 6.4 0.3 0.0 7.3 1.1 26.3 31.8 31.3 6.6 7.8 47.7 6.7 20.1 27.1 3.1 57.8 2.5 11.6 21.4 10.9 21.8 13.5 74.2 2.2 4.1 36.3 63.4 2.0 21.5 48.9 19.6 68.4 41.1 11.6 3.1 136.2 287.1 8.4 1.4 20.7 0.9 32.5 0.1 10.3 4.8 10.5 26.3 34.4 31.6 7.9 12.3 6.3 8.2 11.2 6.3 16.0 0.8 15.0 DENND5B MGC24039 ENSG00000170456 "DENN domain containing 5B" Q6ZUT9 12 31382226-31591136 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 152.8;Excitatory neurons: 217.3;Inhibitory neurons: 246.4;Oligodendrocyte precursor cells: 144.3;Oligodendrocytes: 121.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;naive B-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SuSa: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038865 Approved Approved Nucleoli,Microtubules NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Microtubules Nucleoli "HPA038865: AB_2676245" "unprognostic (5.41e-2)" "unprognostic (2.23e-2)" "unprognostic (4.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "unprognostic (3.08e-2)" "unprognostic (7.23e-2)" "unprognostic (2.13e-1)" "unprognostic (1.16e-2)" "unprognostic (4.96e-2)" "unprognostic (3.14e-1)" "unprognostic (8.27e-2)" "unprognostic (5.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.26e-1)" "unprognostic (2.60e-2)" 4.0 6.4 6.3 5.4 7.8 2.1 3.2 20.1 12.3 4.8 2.9 4.2 9.2 6.9 2.0 2.4 3.9 4.2 10.9 6.1 8.4 7.6 12.5 2.6 7.3 7.7 5.2 21.7 5.7 2.7 4.7 4.9 7.7 2.9 4.3 15.9 2.0 3.1 7.1 1.3 10.4 7.2 2.0 6.7 5.0 16.1 7.1 2.4 2.9 13.1 8.4 3.7 3.1 6.1 2.8 27.9 20.1 7.7 7.1 8.8 3.0 6.8 7.4 16.9 12.1 18.9 11.1 10.4 11.1 14.8 18.5 0.8 4.0 1.9 16.7 0.0 8.5 0.1 21.2 11.3 6.5 9.6 0.2 5.5 6.0 11.3 18.5 15.5 15.7 5.7 4.0 20.6 10.6 2.6 5.7 10.0 20.4 6.5 4.9 5.4 27.8 0.2 14.2 3.6 6.4 9.5 17.0 1.9 15.0 57.3 2.8 5.2 16.5 6.3 16.0 11.4 14.4 10.9 13.0 10.5 10.7 1.1 10.7 0.1 0.1 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.2 1.6 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.1 6.3 7.8 20.1 12.3 6.1 8.4 7.7 5.2 7.7 2.0 7.1 6.1 6.7 3.2 0.5 152.8 43.9 2.9 3.5 0.9 2.8 42.4 5.3 4.1 44.0 17.2 2.1 7.3 31.3 0.6 7.0 13.3 3.9 1.8 19.6 6.1 10.1 7.4 8.4 6.3 217.3 9.3 2.9 13.0 4.6 4.4 0.0 45.0 25.0 34.2 4.5 28.6 246.4 3.1 2.0 4.5 5.8 8.3 8.4 3.8 23.2 74.9 2.5 12.9 1.0 144.3 121.0 7.9 3.6 10.5 72.6 2.4 33.2 12.0 2.2 26.8 6.6 12.9 10.0 32.0 18.2 0.2 1.4 0.7 2.3 15.5 4.4 1.2 DENND6A "AFI1A, FAM116A, FLJ34969" ENSG00000174839 "DENN domain containing 6A" Q8IWF6 3 57625454-57693077 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 66.9;Inhibitory neurons: 65.4;Oligodendrocytes: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 18.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 18.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062618, HPA069725, HPA071711" Approved Supported Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA062618: AB_2684809, HPA069725: AB_2686184, HPA071711: AB_2686435" "unprognostic (6.20e-2)" "unprognostic (3.86e-2)" "prognostic favorable (9.21e-4)" "unprognostic (1.76e-1)" "unprognostic (7.75e-2)" "unprognostic (3.17e-1)" "prognostic unfavorable (6.36e-4)" "unprognostic (7.16e-2)" "unprognostic (1.17e-2)" "unprognostic (2.28e-3)" "unprognostic (5.97e-3)" "unprognostic (1.12e-1)" "prognostic favorable (7.77e-6)" "unprognostic (3.06e-1)" "unprognostic (1.63e-1)" "unprognostic (3.61e-3)" "unprognostic (2.94e-1)" 11.6 7.3 3.4 8.8 4.6 12.6 12.9 12.9 7.1 11.8 3.8 10.7 7.1 12.7 9.9 11.4 10.3 8.3 8.0 3.0 5.5 8.9 7.7 10.5 12.6 4.2 4.8 20.9 5.3 11.4 6.6 11.8 5.3 9.9 9.2 10.0 8.4 11.7 7.1 8.6 9.2 11.3 4.7 12.9 9.7 8.0 4.7 11.8 14.0 9.8 10.5 10.7 10.5 8.4 16.8 13.5 18.0 11.0 9.4 10.6 10.2 8.6 11.0 10.5 8.2 8.7 18.4 19.9 3.6 8.9 9.2 8.8 14.4 18.2 8.9 5.1 12.9 15.7 15.1 6.7 9.0 12.1 8.9 11.3 13.0 7.2 18.7 10.6 15.2 21.1 10.8 21.1 7.6 7.3 26.2 14.9 10.2 10.6 9.3 10.9 10.7 14.8 12.8 28.1 6.1 22.0 17.1 13.9 12.5 7.7 9.1 14.7 16.7 12.7 6.8 13.6 22.8 15.7 22.2 20.7 14.8 19.9 18.9 18.7 1.0 1.4 2.4 1.1 2.9 0.8 2.3 2.4 1.3 1.2 3.4 2.6 1.5 1.9 1.4 1.0 1.3 1.0 3.4 4.6 12.9 7.1 3.0 5.5 4.2 4.8 5.3 4.7 4.7 8.4 28.8 19.2 8.2 31.3 14.5 12.9 11.8 10.6 12.0 16.2 9.9 9.1 20.8 11.5 10.0 5.5 8.4 6.4 21.4 5.7 3.9 8.1 22.2 10.1 25.6 16.0 3.0 16.2 66.9 10.9 4.4 15.7 10.2 17.1 2.5 24.1 20.7 11.1 11.1 10.1 65.4 5.5 12.2 34.3 9.9 11.3 11.8 16.8 3.6 47.8 16.8 10.2 20.6 42.3 74.3 18.9 3.5 14.3 9.5 8.4 6.5 8.9 8.0 14.5 6.6 19.2 18.3 13.3 5.0 14.1 10.7 2.3 19.6 16.7 6.1 13.0 DEPP1 "C10orf10, DEPP, FIG, Fseg" ENSG00000165507 "DEPP1 autophagy regulator" Q9NTK1 10 44970981-44978809 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 889.5;breast: 697.2" "Cell type enhanced" "Detected in many" "Adipocytes: 192.0;Ductal cells: 146.3;Exocrine glandular cells: 113.0;Glandular and luminal cells: 87.1;Syncytiotrophoblasts: 300.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 143.2;HDLM-2: 106.7;HHSteC: 258.2;HSkMC: 201.6;HUVEC TERT2: 165.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB013687, HPA037818, HPA037819" Uncertain Supported Vesicles,Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria Vesicles "CAB013687: , HPA037818: , HPA037819: AB_2675685" "unprognostic (3.99e-2)" "unprognostic (4.69e-2)" "unprognostic (5.57e-2)" "unprognostic (3.55e-1)" "unprognostic (1.88e-2)" "unprognostic (5.66e-3)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (4.25e-1)" "unprognostic (5.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.89e-2)" "prognostic unfavorable (2.29e-6)" "unprognostic (2.30e-3)" "unprognostic (2.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.74e-1)" 889.5 48.4 62.3 19.4 71.4 4.5 697.2 59.5 71.8 153.0 50.3 145.7 16.7 168.5 16.5 65.7 334.2 68.5 260.6 55.5 71.9 95.4 131.6 508.6 63.0 175.9 72.3 297.8 349.7 23.0 85.2 76.5 93.4 82.6 12.0 28.2 119.7 22.8 165.8 165.0 94.8 68.8 101.6 32.8 104.6 19.3 87.4 25.2 200.5 52.2 47.6 177.6 139.1 90.6 30.2 0.2 0.5 0.4 143.2 69.5 7.4 0.2 10.2 0.4 1.8 1.1 11.2 0.0 1.6 13.5 7.1 1.2 1.2 9.1 0.7 106.7 4.0 0.1 0.1 11.0 258.2 0.1 0.1 201.6 0.4 0.1 1.4 24.9 165.0 0.0 0.2 63.2 0.6 0.0 0.1 1.7 0.2 0.6 0.9 5.1 1.7 25.7 0.5 10.9 5.6 0.3 0.0 1.3 5.8 17.0 0.2 7.0 1.6 7.8 5.6 0.5 7.3 1.7 2.8 0.4 44.2 2.6 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.4 62.3 71.4 59.5 71.8 55.5 71.9 175.9 72.3 93.4 101.6 87.4 90.6 192.0 0.0 24.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 47.0 27.8 0.0 0.0 6.2 31.3 0.0 53.8 1.4 0.0 37.2 146.3 0.0 61.3 33.2 60.0 0.0 0.0 0.0 113.0 14.7 79.3 0.0 87.1 0.0 8.4 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 65.0 0.0 0.0 0.5 0.0 0.0 25.5 5.8 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 300.2 1.8 0.8 0.0 0.0 DERL3 "C22orf14, derlin-3, FLJ43842, IZP6, MGC71803" ENSG00000099958 "Derlin 3" Q96Q80 22 23834503-23839128 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.6;pancreas: 60.8;salivary gland: 51.1" "Cell type enriched" "Detected in many" 6 "Plasma cells: 1428.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "plasmacytoid DC: 187.4" "Lineage enriched" "Detected in many" 14 "dendritic cells: 187.4" "Cell line enhanced" "Detected in some" "Karpas-707: 26.9;RPMI-8226: 23.6;U-266/70: 48.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB037234, HPA049306" Approved Uncertain Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB037234: AB_1840802, HPA049306: " "unprognostic (2.01e-3)" "prognostic favorable (8.70e-5)" "unprognostic (9.72e-3)" "unprognostic (7.47e-2)" "unprognostic (9.77e-3)" "prognostic favorable (8.01e-4)" "unprognostic (2.23e-2)" "unprognostic (1.40e-1)" "unprognostic (1.36e-1)" "unprognostic (8.66e-3)" "unprognostic (4.74e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.76e-13)" "unprognostic (1.53e-2)" "unprognostic (4.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.95e-1)" 2.6 3.2 1.4 4.3 1.4 1.8 5.4 1.3 2.2 6.1 1.9 30.6 10.0 3.7 0.2 4.3 7.1 2.3 7.7 1.3 1.6 5.7 9.1 9.2 9.2 1.8 2.2 2.0 60.8 0.8 8.1 0.8 1.7 3.3 10.9 0.2 51.1 3.8 2.7 0.8 33.7 0.7 1.7 61.6 29.4 24.8 1.7 1.6 14.6 0.2 17.6 3.6 2.3 1.5 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 4.5 4.8 0.9 0.0 1.4 0.0 1.1 1.3 0.0 0.5 4.8 0.4 4.6 0.0 0.7 3.2 0.6 0.0 0.2 0.5 0.0 0.1 0.1 0.5 0.8 26.9 0.0 0.0 1.3 2.2 1.0 2.3 0.3 4.2 0.0 23.6 0.9 0.3 0.6 0.1 0.1 0.0 0.2 0.7 0.0 1.5 0.0 0.0 0.0 0.4 0.1 48.5 6.3 8.3 0.8 6.2 0.1 0.0 0.0 0.0 0.2 0.1 0.2 13.8 0.0 0.0 0.0 12.4 0.1 0.0 0.1 0.0 0.0 187.4 0.0 1.3 1.4 1.4 1.3 2.2 1.3 1.6 1.8 2.2 1.7 1.7 1.7 1.5 0.5 0.0 1.1 0.3 183.8 1.8 1.5 3.7 0.6 1.1 19.3 1.8 3.5 1.5 4.1 0.0 2.1 0.8 141.7 2.7 0.0 0.5 113.2 33.8 0.9 1.1 1.8 8.2 0.3 5.8 6.2 2.2 7.7 1.7 2.5 15.7 4.6 7.8 3.4 0.0 1.7 7.9 4.1 2.2 2.1 158.2 2.5 5.4 224.1 1.9 0.5 0.8 0.0 1.0 0.5 1.1 0.5 4.1 1428.8 2.5 0.8 0.5 30.3 0.6 0.0 0.8 2.6 67.0 32.9 1.3 2.0 15.5 17.9 2.1 10.7 2.0 DEUP1 "CCDC67, FLJ25393" ENSG00000165325 "Deuterosome assembly protein 1" Q05D60 11 93329971-93438487 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.8;testis: 16.4" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 16.8;Respiratory ciliated cells: 21.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (4.68e-1)" "unprognostic (3.25e-1)" "unprognostic (3.93e-1)" "unprognostic (7.24e-3)" "unprognostic (2.09e-1)" "unprognostic (4.13e-1)" "unprognostic (2.29e-1)" "unprognostic (1.79e-2)" "unprognostic (1.16e-1)" "unprognostic (1.84e-1)" "unprognostic (1.25e-1)" "unprognostic (1.41e-3)" "unprognostic (1.33e-1)" "unprognostic (6.03e-3)" "unprognostic (8.59e-2)" "unprognostic (2.25e-1)" 0.0 0.5 0.4 0.0 0.2 0.0 0.4 0.0 0.1 0.0 1.8 0.1 0.0 0.0 1.1 0.0 4.8 0.1 0.0 0.4 2.1 0.3 0.0 0.3 0.0 0.7 1.1 0.3 0.8 0.3 1.5 0.0 0.6 0.9 0.1 0.1 0.2 0.3 0.0 0.2 0.0 0.1 0.5 0.1 0.0 16.4 3.6 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.4 2.1 0.7 1.1 0.6 0.5 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.0 16.8 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 21.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DGKD "DGKdelta, KIAA0145" ENSG00000077044 "Diacylglycerol kinase delta" Q16760 2 233354494-233472104 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 30.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 143.2;Inhibitory neurons: 137.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 17.3;HeLa: 21.8;U-698: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027530, HPA049101" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA027530: AB_2672320, HPA049101: AB_2680630" "unprognostic (1.84e-1)" "unprognostic (2.19e-2)" "unprognostic (7.76e-3)" "unprognostic (1.92e-2)" "unprognostic (5.69e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (6.03e-2)" "unprognostic (5.76e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.07e-8)" "unprognostic (1.78e-1)" "unprognostic (7.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.94e-3)" 5.2 3.4 4.3 1.9 5.5 12.0 5.9 20.5 6.2 4.5 3.2 9.0 1.6 5.9 1.6 2.2 5.7 1.0 7.6 5.8 4.0 2.5 3.6 10.6 4.3 6.5 3.9 8.9 2.7 0.4 3.7 2.9 7.4 5.7 2.3 5.4 5.9 0.5 30.4 3.0 12.9 0.7 4.1 11.4 25.2 9.6 4.4 1.0 8.3 0.9 4.5 5.3 2.6 8.8 1.7 8.5 2.1 1.5 1.5 1.4 3.0 2.4 1.0 0.6 0.5 9.7 1.9 10.3 1.1 2.4 4.5 2.0 2.4 1.0 3.2 17.3 11.3 4.7 21.8 5.8 0.9 11.7 7.2 2.3 2.2 1.1 2.1 1.8 0.8 2.1 7.8 1.8 1.6 3.1 9.2 3.3 1.6 2.8 6.9 14.5 5.7 1.6 0.9 3.3 2.1 2.2 1.4 2.3 1.0 1.8 0.6 5.2 1.0 1.2 3.0 1.2 1.7 7.1 6.2 22.7 0.8 5.6 0.6 1.7 1.6 5.6 2.1 0.6 1.1 4.8 0.5 1.5 0.4 5.0 1.7 2.4 1.2 0.6 1.0 0.4 0.2 1.7 4.3 5.5 20.5 6.2 5.8 4.0 6.5 3.9 7.4 4.1 4.4 8.8 18.9 32.1 46.2 27.1 61.1 8.9 6.4 5.6 4.6 33.8 19.6 11.6 21.0 0.0 13.8 0.0 62.6 14.6 62.0 40.6 0.0 3.6 14.9 23.4 12.5 19.1 2.4 5.0 11.1 4.4 1.2 9.7 143.2 38.1 5.7 13.1 4.6 7.0 6.8 8.4 137.9 32.8 8.2 10.4 13.8 38.7 6.5 28.7 8.8 11.2 17.5 13.9 49.4 43.2 81.5 26.0 13.5 4.5 34.7 17.6 29.6 2.6 4.8 44.3 19.7 49.4 21.2 14.4 29.3 4.5 3.7 2.5 32.5 7.6 20.1 9.9 DGKH DGKeta ENSG00000102780 "Diacylglycerol kinase eta" Q86XP1 13 42040036-42256578 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 137.8;Urothelial cells: 147.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 25.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039533, HPA040355, HPA061538" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "HPA039533: AB_10795145, HPA040355: AB_10796452, HPA061538: " "unprognostic (2.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.30e-1)" "unprognostic (5.69e-2)" "unprognostic (1.55e-3)" "unprognostic (7.62e-2)" "unprognostic (1.04e-2)" "unprognostic (9.60e-2)" "unprognostic (7.00e-3)" "unprognostic (4.37e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (3.43e-3)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (4.93e-2)" "unprognostic (1.43e-2)" 3.7 1.3 4.5 2.0 25.8 1.3 3.5 8.7 5.4 4.4 0.0 3.7 1.5 6.4 6.9 4.1 4.3 2.5 3.0 7.3 4.4 3.3 1.0 7.8 2.2 0.0 7.4 2.8 1.0 0.7 2.6 4.5 0.4 2.8 3.3 2.6 3.0 2.1 1.5 3.2 2.7 4.0 0.2 1.7 2.6 2.3 9.7 2.7 2.5 2.2 1.3 5.3 4.6 2.8 5.6 6.6 4.3 3.6 1.9 4.2 0.5 3.4 2.7 2.2 2.8 0.6 4.7 4.3 4.1 3.7 8.3 11.8 3.8 7.7 3.3 3.4 12.4 7.6 3.6 0.4 2.4 3.3 2.0 1.6 7.7 4.3 17.0 3.4 9.9 5.3 3.0 2.9 3.8 5.1 3.4 1.7 1.9 5.2 4.3 5.0 3.8 2.9 7.4 16.7 2.5 2.6 3.1 4.0 3.0 1.8 3.4 8.9 9.8 4.1 3.8 4.5 4.7 1.5 1.5 4.8 2.4 2.9 3.1 0.6 0.3 0.1 0.2 0.2 0.2 0.1 0.4 0.4 0.0 0.2 0.2 0.4 0.9 0.1 0.1 0.3 0.3 0.1 4.5 25.8 8.7 5.4 7.3 4.4 0.0 7.4 0.4 0.2 9.7 2.8 64.8 22.4 20.1 8.8 1.9 61.7 58.1 61.1 15.9 44.5 13.6 8.9 8.5 24.3 44.7 11.0 4.2 3.7 2.2 29.0 1.9 11.3 25.9 64.1 26.0 50.8 47.4 2.7 85.4 7.2 2.2 17.5 15.3 46.2 7.6 5.7 23.2 3.2 6.8 1.7 60.2 18.7 14.2 5.6 43.1 20.1 3.4 8.0 8.8 56.2 8.6 18.8 1.0 54.3 11.0 27.6 19.2 9.1 6.2 137.8 13.1 8.4 91.8 2.6 26.3 16.2 54.1 3.8 3.8 19.7 33.1 2.9 13.0 11.5 22.0 147.3 DGKI DGK-IOTA ENSG00000157680 "Diacylglycerol kinase iota" O75912 7 137381037-137847092 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 19.2;choroid plexus: 9.2;retina: 6.5;thyroid gland: 15.6" "Group enriched" "Detected in some" 5 "Excitatory neurons: 606.4;Inhibitory neurons: 414.6;Oligodendrocyte precursor cells: 329.2" "Group enriched" "Detected in some" 4 "glioma: 0.8;melanoma: 0.6;renal cancer: 1.0;thyroid cancer: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 3.0;GAMG: 3.6;hTEC/SVTERT24-B: 3.2;SCLC-21H: 5.0;U-2197: 14.1;U-87 MG: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.76e-1)" "unprognostic (1.22e-1)" "unprognostic (6.66e-3)" "unprognostic (1.76e-1)" "unprognostic (6.08e-2)" "unprognostic (1.42e-1)" "unprognostic (9.62e-2)" "unprognostic (2.23e-1)" "unprognostic (1.09e-1)" "unprognostic (9.01e-2)" "unprognostic (8.74e-2)" "unprognostic (4.46e-2)" "unprognostic (5.98e-5)" "unprognostic (2.85e-3)" "unprognostic (1.85e-1)" "unprognostic (1.26e-2)" "unprognostic (1.73e-3)" 0.5 0.3 4.5 0.2 19.2 0.0 0.2 1.0 11.8 0.1 9.2 0.3 0.0 0.3 0.1 0.0 0.1 0.6 2.8 6.1 2.9 0.5 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.2 1.3 0.0 1.5 0.1 0.1 6.5 0.3 0.1 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.6 6.5 0.0 15.6 0.0 0.0 0.2 0.0 8.2 0.0 0.0 0.4 0.0 0.8 0.6 0.0 3.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.9 3.6 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.1 0.2 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 2.3 0.0 0.0 0.5 0.2 0.0 0.0 0.1 1.3 0.5 14.1 0.6 0.1 0.0 0.0 5.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 19.2 1.0 11.8 6.1 2.9 0.1 4.7 1.5 0.0 6.5 8.2 0.3 0.0 0.0 7.5 0.3 1.1 0.2 1.4 0.6 53.1 1.0 0.1 11.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.4 1.3 1.1 0.0 0.0 606.4 0.0 0.0 2.1 0.0 0.3 0.0 0.1 0.4 0.0 0.6 45.4 414.6 0.0 44.7 0.0 0.7 3.6 0.9 0.2 0.0 60.9 0.0 2.1 1.0 329.2 84.4 0.0 0.0 1.5 0.0 0.2 0.0 0.3 0.2 3.3 0.0 0.8 2.2 0.2 0.5 0.2 0.6 0.0 0.1 0.5 0.0 0.0 DGKZ "DAGK5, DAGK6, DGK-ZETA, hDGKzeta" ENSG00000149091 "Diacylglycerol kinase zeta" Q13574 11 46332905-46380554 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 146.2" "Cell type enhanced" "Detected in all" "NK-cells: 129.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 27 "amygdala: 46.5;basal ganglia: 75.1;cerebral cortex: 146.2;hippocampal formation: 133.8;white matter: 51.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051336 Enhanced Supported Supported "Nuclear speckles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "HPA051336: AB_2681448" "unprognostic (2.85e-2)" "unprognostic (3.90e-2)" "unprognostic (2.39e-1)" "unprognostic (1.65e-1)" "unprognostic (1.40e-1)" "unprognostic (4.12e-2)" "unprognostic (3.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (2.49e-2)" "unprognostic (3.66e-3)" "unprognostic (8.18e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.48e-3)" "unprognostic (7.75e-2)" "unprognostic (3.61e-2)" "unprognostic (7.84e-3)" 20.7 14.2 46.5 21.6 75.1 54.6 19.4 3.3 146.2 16.5 0.0 20.3 36.4 16.8 4.0 19.5 15.3 11.1 46.5 133.8 0.0 18.3 10.5 18.3 39.9 0.0 0.0 12.4 31.5 10.0 58.7 14.1 0.0 18.6 6.6 2.5 43.4 10.7 95.7 22.3 41.2 9.1 0.0 36.1 22.2 15.4 1.4 34.0 12.5 25.1 17.1 18.2 15.3 51.0 38.1 33.2 22.1 33.2 11.5 12.8 102.1 29.0 21.5 30.0 26.3 39.8 17.1 48.4 20.5 30.1 33.0 43.3 26.7 42.0 10.6 48.8 62.5 31.7 25.2 29.5 20.5 60.5 61.2 17.3 19.3 16.5 22.2 15.3 33.4 39.3 45.1 29.1 21.5 99.8 58.6 94.3 64.3 54.5 50.3 69.0 38.2 20.6 9.1 36.6 150.3 25.6 33.2 109.6 23.0 13.8 78.8 75.2 37.9 39.2 42.4 62.6 52.9 19.1 23.4 40.3 53.8 54.0 37.2 12.4 13.5 6.0 6.8 5.6 4.1 0.3 4.3 5.9 12.0 0.8 4.3 4.6 9.5 7.6 6.4 5.7 4.4 10.5 46.5 75.1 3.3 146.2 133.8 0.0 0.0 0.0 0.0 0.0 1.4 51.0 46.0 3.2 6.6 44.7 16.4 13.3 22.3 16.3 14.2 27.6 24.6 19.8 24.4 8.6 8.7 9.2 20.9 14.6 95.8 37.7 9.8 13.2 6.1 9.9 15.2 34.2 51.5 23.4 114.0 47.8 105.1 12.4 34.1 14.1 21.0 25.7 56.7 7.1 51.2 16.8 45.0 26.3 22.4 46.1 26.9 11.4 13.1 34.0 12.4 31.9 50.6 6.4 129.8 8.5 24.7 33.5 41.0 8.2 25.3 16.6 97.0 20.2 8.2 9.9 32.9 17.8 16.8 7.0 12.2 12.3 9.2 27.4 71.8 19.4 29.9 17.2 DHFR ENSG00000228716 "Dihydrofolate reductase" P00374 5 80626226-80654983 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methotrexate resistance, One-carbon metabolism" "Oxidoreductase, RNA-binding" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 145.8;Spermatocytes: 132.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037129, HPA051465" Uncertain Approved Mitochondria NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "CAB037129: AB_439683, HPA051465: AB_2681494" "unprognostic (1.44e-2)" "unprognostic (1.03e-2)" "unprognostic (2.24e-3)" "unprognostic (2.91e-3)" "unprognostic (3.27e-1)" "unprognostic (1.32e-1)" "unprognostic (2.83e-2)" "unprognostic (2.35e-2)" "unprognostic (2.02e-2)" "unprognostic (4.19e-3)" "unprognostic (1.83e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (1.82e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" 25.2 5.3 15.3 20.7 16.5 54.3 12.0 15.8 21.9 8.0 13.3 21.4 24.5 8.6 7.0 14.1 7.4 8.5 7.2 13.8 15.5 21.3 60.1 7.5 41.5 16.6 16.6 6.6 3.2 9.1 6.3 14.4 16.6 8.9 25.3 10.3 6.8 9.5 19.6 9.8 25.1 12.0 16.5 10.3 12.2 18.5 15.8 60.7 8.2 25.8 39.5 10.3 5.7 17.7 98.1 66.6 164.8 122.7 30.7 32.0 60.6 76.5 58.1 130.2 149.0 63.8 114.6 196.9 32.5 44.6 106.0 67.0 214.4 98.6 208.5 88.2 132.1 94.8 104.5 59.5 6.6 111.7 40.3 22.3 9.9 116.9 13.0 22.2 63.9 142.0 108.3 146.7 133.5 98.2 276.5 44.9 83.6 48.3 38.5 176.7 323.3 194.1 75.1 61.5 134.3 93.7 107.9 49.9 54.6 83.5 98.5 108.6 38.5 41.0 62.0 116.0 148.3 68.2 146.6 210.3 91.5 222.1 107.7 0.2 0.3 0.2 0.5 0.6 0.2 0.5 0.6 0.8 0.5 0.5 0.5 0.6 0.8 0.5 0.5 0.8 0.9 0.6 15.3 16.5 15.8 21.9 13.8 15.5 16.6 16.6 16.6 16.5 15.8 17.7 4.1 6.4 11.7 4.9 21.4 6.9 6.5 6.0 4.0 3.5 8.9 8.9 13.0 4.3 6.1 14.7 2.1 35.2 7.4 19.3 9.8 7.4 7.4 10.8 7.7 7.7 4.9 145.8 7.3 3.7 47.3 12.0 11.7 8.0 2.5 22.0 10.0 48.3 44.7 3.3 7.2 19.1 4.1 18.9 4.4 6.4 14.0 12.8 0.0 4.7 7.1 14.5 13.4 3.5 6.0 4.7 10.3 16.1 60.9 2.9 26.6 40.0 6.9 3.2 13.1 9.0 12.5 132.2 49.8 21.2 5.5 13.3 11.8 12.3 38.1 12.1 DHFR2 "DHFRL1, DHFRP4, FLJ16119" ENSG00000178700 "Dihydrofolate reductase 2" Q86XF0 3 94047836-94063389 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Ductal cells: 6.3;Respiratory ciliated cells: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 13 "hTERT-RPE1: 154.6" HPA051465 Uncertain Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA051465: AB_2681494" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-2)" "unprognostic (3.50e-2)" "unprognostic (2.07e-1)" "unprognostic (1.38e-1)" "unprognostic (5.92e-2)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (4.62e-2)" "unprognostic (2.95e-1)" "unprognostic (1.52e-1)" "prognostic favorable (2.30e-6)" "unprognostic (1.63e-1)" "unprognostic (1.79e-1)" "unprognostic (1.13e-1)" "unprognostic (2.96e-2)" 3.3 4.9 3.9 3.8 5.2 1.8 5.3 6.0 5.2 5.2 4.8 4.2 4.1 7.9 6.4 3.5 6.3 5.1 3.7 4.1 4.1 5.9 6.7 4.5 5.7 4.8 4.2 10.1 5.3 6.5 2.5 3.2 5.0 6.4 4.6 3.2 4.4 4.9 1.4 4.2 4.9 5.4 4.2 4.9 4.7 4.7 4.4 5.7 6.7 2.1 4.6 3.3 2.4 6.5 3.8 6.5 4.2 4.4 5.7 7.2 1.7 5.7 6.0 2.8 3.2 1.4 5.7 2.5 3.8 3.0 3.7 5.0 3.3 3.9 4.4 8.5 1.8 3.1 2.9 3.4 6.0 2.2 3.6 7.6 5.1 3.3 4.2 154.6 2.9 11.9 1.6 5.6 3.7 4.5 10.8 1.2 3.7 10.8 6.7 2.7 5.7 4.1 4.1 1.9 5.4 5.3 8.3 2.2 9.6 3.3 5.6 3.1 4.8 4.4 7.4 1.8 2.2 4.1 4.4 3.5 4.4 5.5 6.2 2.2 1.1 2.0 1.8 1.7 3.3 1.8 2.4 2.9 0.7 2.2 3.2 3.0 1.7 1.4 1.8 2.1 3.2 1.3 3.9 5.2 6.0 5.2 4.1 4.1 4.8 4.2 5.0 4.2 4.4 6.5 2.8 12.8 5.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.6 3.4 0.0 0.0 1.8 3.7 0.0 2.4 2.3 0.0 3.9 6.3 0.0 3.5 4.4 2.5 0.0 0.0 0.0 5.5 1.7 2.5 0.0 2.9 2.5 4.9 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 0.0 0.0 5.6 8.7 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.8 1.3 3.5 0.0 0.0 DHH "HHG-3, MGC35145" ENSG00000139549 "Desert hedgehog signaling molecule" O43323 12 49086656-49094801 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 16.7" "Cell type enriched" "Detected in some" 7 "Granulosa cells: 17.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "AN3-CA: 1.8;EFO-21: 2.3;HUVEC TERT2: 1.5;K-562: 5.6;TIME: 2.7" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "spinal cord: 8.2" "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.56e-2)" "unprognostic (2.05e-3)" "unprognostic (1.14e-1)" "unprognostic (2.93e-3)" "unprognostic (2.36e-4)" "unprognostic (1.29e-1)" "unprognostic (7.22e-3)" "unprognostic (8.21e-2)" "unprognostic (5.92e-2)" "unprognostic (1.22e-1)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (8.00e-2)" "unprognostic (1.00e-1)" "unprognostic (6.97e-2)" 0.8 0.2 0.2 0.5 0.3 0.0 0.7 0.7 0.5 0.5 0.1 0.4 0.0 0.6 0.2 0.3 0.4 0.3 0.6 0.2 0.1 0.7 0.1 0.5 0.1 0.5 0.4 0.3 0.1 0.0 0.6 0.6 0.4 0.4 0.1 0.0 0.3 0.3 0.1 0.3 0.4 0.4 0.6 0.2 0.3 16.7 0.4 0.0 0.3 0.4 0.0 0.7 0.5 0.8 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.5 0.2 0.1 0.5 0.4 0.4 0.6 0.4 0.8 1.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 17.1 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.0 0.7 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 DHRS7 "retDSR4, SDR34C1" ENSG00000100612 "Dehydrogenase/reductase 7" Q9Y394 14 60144119-60169856 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 615.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 840.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 199.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031121, HPA078401" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Mitochondria" "HPA031121: AB_10600803, HPA078401: " "prognostic favorable (6.42e-4)" "unprognostic (5.20e-2)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (4.65e-2)" "unprognostic (4.31e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.92e-10)" "unprognostic (8.35e-3)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" 62.1 103.4 50.8 43.8 53.9 61.0 58.5 59.2 75.4 48.9 50.2 73.0 108.9 49.8 96.5 44.3 45.9 59.1 47.1 49.9 55.1 100.5 146.4 64.2 45.5 62.3 54.9 64.9 76.8 226.8 54.7 29.6 63.3 409.9 69.5 111.1 317.5 134.6 615.8 46.6 181.0 51.0 57.8 45.4 182.3 9.8 52.0 39.2 120.3 136.0 49.4 51.7 41.1 65.6 221.3 52.9 41.8 89.3 219.6 74.4 42.8 74.3 186.4 26.5 59.0 37.3 149.8 21.5 41.7 76.8 78.0 92.7 57.2 108.3 34.5 156.1 36.0 53.7 28.7 60.9 110.1 71.8 1.7 63.3 116.7 47.6 153.0 50.8 52.5 66.2 18.2 52.6 61.4 59.2 40.9 67.2 18.6 151.2 55.4 42.7 50.8 24.4 118.3 70.5 83.4 99.8 72.6 118.0 168.2 52.7 72.7 32.5 35.8 126.6 38.7 36.9 44.2 18.3 7.9 45.0 62.6 64.8 93.5 743.5 213.1 519.6 335.7 159.1 340.6 184.4 238.9 298.5 185.0 167.0 134.6 258.5 835.4 294.7 224.0 388.8 215.5 450.2 50.8 53.9 59.2 75.4 49.9 55.1 62.3 54.9 63.3 57.8 52.0 65.6 109.6 54.5 102.5 16.0 72.2 34.0 70.3 233.2 52.3 25.7 81.2 57.4 27.6 160.2 138.4 86.5 83.4 29.6 210.4 101.3 19.6 222.5 2.1 56.2 55.5 89.7 46.5 20.4 12.2 165.9 88.7 87.9 120.8 120.0 178.5 22.9 48.5 166.4 94.4 42.1 19.0 102.2 386.6 54.5 70.6 3.5 82.3 98.7 108.5 16.9 172.5 94.4 299.7 26.2 20.1 210.6 114.5 84.2 99.0 263.4 840.4 44.1 57.0 70.7 85.5 66.4 73.7 1.6 2.9 47.0 25.4 20.8 152.1 19.7 79.2 47.1 DHRS7C SDR32C2 ENSG00000184544 "Dehydrogenase/reductase 7C" A6NNS2 17 9771434-9791592 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 66 "heart muscle: 125.0;skeletal muscle: 308.1;tongue: 367.4" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 87.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (6.83e-2)" 0.1 0.1 0.4 0.0 0.5 0.0 0.1 0.3 1.1 0.0 0.3 0.4 0.2 0.0 0.0 4.0 0.0 0.0 125.0 0.5 0.3 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.1 0.0 0.2 0.0 0.3 0.5 1.1 0.0 2.9 0.0 308.1 0.0 0.2 0.0 0.4 0.0 0.0 0.6 0.3 0.0 0.0 367.4 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.3 1.1 0.5 0.3 0.3 0.3 0.3 0.4 0.3 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 14.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DHRS9 "3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4" ENSG00000073737 "Dehydrogenase/reductase 9" Q9BPW9 2 169064789-169096167 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.9;intestine: 70.4" "Cell type enhanced" "Detected in many" "Club cells: 229.3;Distal enterocytes: 261.2;Early spermatids: 153.2;Paneth cells: 299.9;Respiratory ciliated cells: 155.9;Syncytiotrophoblasts: 267.5;Urothelial cells: 249.2" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 258.3;eosinophil: 99.2;neutrophil: 77.3" "Lineage enriched" "Detected in many" 10 "granulocytes: 258.3" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 22.8;HUVEC TERT2: 21.5;NB-4: 33.7;THP-1: 98.0;TIME: 49.9;U-2197: 31.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036491, HPA036667" Approved "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036491: AB_10673498, HPA036667: AB_10670237" "unprognostic (1.15e-1)" "unprognostic (3.82e-3)" "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (4.80e-2)" "unprognostic (2.35e-1)" "unprognostic (3.24e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (3.62e-4)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.72e-1)" "unprognostic (3.23e-1)" "unprognostic (1.85e-2)" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-1)" 10.0 0.2 2.2 12.5 2.4 8.5 5.1 3.0 2.6 8.6 1.6 70.4 1.9 1.2 0.9 28.2 1.0 5.7 53.9 2.5 2.3 0.3 3.1 7.1 20.2 4.2 3.2 0.7 0.4 0.2 0.4 2.8 4.3 0.8 46.2 1.2 6.1 0.5 0.3 3.3 5.7 4.2 3.8 7.6 10.8 11.3 3.2 2.2 0.3 0.8 26.8 17.5 10.1 4.5 0.0 0.7 0.0 0.0 2.5 10.2 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.0 6.5 1.7 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 8.9 1.0 0.4 0.5 1.3 6.1 22.8 21.5 0.0 1.0 0.0 0.0 0.0 0.1 33.7 0.0 0.3 8.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 98.0 49.9 0.1 0.2 31.4 0.2 0.1 0.0 0.0 0.8 18.9 0.0 258.3 21.0 99.2 0.0 25.0 0.6 6.5 0.0 0.0 21.6 5.0 0.1 0.0 77.3 0.4 5.1 1.6 0.0 5.9 2.2 2.4 3.0 2.6 2.5 2.3 4.2 3.2 4.3 3.8 3.2 4.5 0.3 0.0 1.3 0.0 1.4 1.7 19.3 72.4 0.0 0.0 0.1 0.4 24.4 0.0 229.3 0.0 0.0 2.5 0.0 261.2 0.0 4.6 153.2 0.5 0.0 0.6 1.8 0.8 0.2 25.3 1.3 1.5 7.7 0.1 91.0 0.0 0.0 0.6 25.0 0.0 0.2 51.6 36.7 10.2 38.8 45.5 1.2 16.6 0.0 19.7 3.5 3.9 0.0 0.0 0.2 68.6 299.9 0.4 6.4 6.5 1.5 0.1 155.9 0.1 6.6 0.2 10.9 1.1 0.6 0.3 1.4 267.5 3.8 0.0 8.2 249.2 DHX29 DDX29 ENSG00000067248 "DExH-box helicase 29" Q7Z478 5 55256055-55307694 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Helicase, Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038317, HPA038318" Approved Approved Cytosol "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA038317: AB_10673169, HPA038318: AB_10672589" "unprognostic (3.43e-2)" "unprognostic (5.09e-1)" "unprognostic (2.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.80e-1)" "unprognostic (2.37e-3)" "unprognostic (1.72e-1)" "unprognostic (6.66e-2)" "unprognostic (1.76e-2)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.57e-3)" "unprognostic (4.01e-1)" "unprognostic (3.85e-1)" "unprognostic (4.78e-3)" "unprognostic (9.40e-2)" 10.6 10.6 5.3 9.7 5.7 6.7 12.0 9.1 7.0 12.5 6.7 12.1 7.2 11.4 6.8 12.7 9.5 8.9 10.7 5.7 5.1 16.9 13.1 9.4 9.5 5.0 5.0 8.9 11.7 18.7 10.4 11.4 5.1 13.4 9.8 8.7 10.3 12.0 24.2 11.6 8.4 12.6 5.5 7.9 10.4 7.4 5.1 10.0 15.4 14.8 9.7 12.0 10.3 7.1 36.7 25.5 20.9 27.2 32.3 28.2 25.6 38.9 30.9 28.2 28.7 21.3 23.0 20.7 34.9 44.5 35.8 26.0 34.0 37.1 40.5 9.1 19.4 18.8 21.6 14.6 18.3 13.3 19.6 23.8 23.0 29.9 17.2 18.5 37.9 16.5 24.4 15.0 33.4 25.9 21.4 11.1 17.5 10.5 27.1 10.9 31.8 35.7 23.0 25.3 19.6 12.5 37.4 21.3 18.6 20.5 28.7 21.7 32.9 25.9 20.2 22.8 27.4 13.2 24.1 29.0 29.9 23.0 29.1 68.6 22.5 24.3 18.0 24.4 20.4 27.3 22.5 20.0 17.5 26.3 25.0 21.6 20.6 24.5 30.1 36.8 21.9 8.9 5.3 5.7 9.1 7.0 5.7 5.1 5.0 5.0 5.1 5.5 5.1 7.1 44.5 70.5 42.6 34.0 35.2 37.6 37.5 71.8 39.3 81.6 44.9 49.8 73.6 41.5 69.4 64.4 41.7 68.3 39.5 34.4 54.8 61.4 54.8 37.4 61.5 40.7 38.4 68.4 47.3 61.7 54.6 52.7 35.7 36.5 31.6 39.0 22.9 45.0 41.2 42.1 46.9 36.4 63.1 26.0 26.6 16.6 46.6 41.5 28.4 28.1 50.7 35.7 35.0 42.7 54.9 61.9 27.3 53.0 57.0 53.2 35.2 105.2 35.9 83.6 52.6 52.8 54.2 117.5 108.1 50.1 47.5 81.3 36.1 106.4 39.9 43.3 DHX30 "DDX30, FLJ11214, KIAA0890" ENSG00000132153 "DExH-box helicase 30" Q7L2E3 3 47802909-47850195 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ribosome biogenesis" "Helicase, Hydrolase, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034806 Supported Supported Mitochondria,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria Cytosol "HPA034806: AB_10601364" "unprognostic (2.00e-1)" "unprognostic (8.37e-2)" "unprognostic (3.27e-1)" "unprognostic (2.14e-2)" "unprognostic (3.04e-1)" "unprognostic (1.62e-1)" "unprognostic (1.27e-3)" "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (1.10e-3)" "unprognostic (1.42e-2)" "prognostic favorable (1.37e-6)" "unprognostic (4.12e-2)" "unprognostic (1.43e-1)" "unprognostic (2.81e-1)" "unprognostic (2.22e-1)" 22.6 24.6 23.7 17.1 23.3 22.2 22.9 21.4 26.3 26.4 24.8 26.8 16.2 27.6 10.4 23.6 24.8 14.9 28.8 23.5 22.4 26.8 25.2 21.3 20.1 24.0 23.5 27.9 24.1 28.9 32.1 17.5 24.6 26.6 10.9 12.7 21.6 18.2 37.1 27.6 22.3 15.9 20.3 27.3 25.2 54.2 23.8 23.3 24.8 21.0 14.3 25.2 22.8 24.2 21.9 52.3 54.5 56.2 24.6 20.2 35.3 39.0 33.4 65.1 46.5 56.9 42.6 66.4 32.0 37.0 51.2 30.3 73.7 52.1 23.1 49.6 86.1 59.6 76.0 58.6 40.7 56.0 58.3 33.0 33.4 68.1 49.7 28.4 44.0 57.5 82.0 40.6 31.8 57.1 82.2 59.3 60.7 30.2 84.0 44.6 30.6 62.2 32.0 53.6 41.6 61.6 39.6 54.1 31.1 25.0 38.5 58.8 32.2 40.6 51.0 46.7 73.9 56.2 75.3 61.8 42.8 48.3 49.9 14.1 10.7 7.8 16.2 10.6 12.4 10.4 12.4 16.3 13.9 8.7 11.7 12.7 1.6 9.6 11.6 7.9 15.3 14.7 23.7 23.3 21.4 26.3 23.5 22.4 24.0 23.5 24.6 20.3 23.8 24.2 31.1 38.5 46.7 30.7 34.7 18.1 25.7 38.7 39.3 49.0 34.6 35.6 38.1 32.9 34.1 51.5 43.8 41.7 33.1 37.6 66.5 37.8 129.5 59.2 31.7 32.4 40.1 38.5 32.8 36.3 22.8 26.7 42.3 33.2 23.5 40.7 27.5 50.8 35.9 58.9 36.6 25.8 40.7 29.6 17.6 123.8 24.8 24.4 19.6 13.1 32.5 46.3 28.8 22.1 28.7 46.0 41.0 30.1 39.9 28.6 40.5 83.5 49.9 52.8 32.9 27.3 28.6 145.4 50.2 33.5 19.9 29.6 29.7 36.6 38.5 26.3 DHX8 "DDX8, Dhr2, HRH1, PRP22, PRPF22" ENSG00000067596 "DEAH-box helicase 8" Q14562 17 43483865-43610338 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049285 Approved Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nuclear bodies" "HPA049285: AB_2680698" "unprognostic (2.99e-1)" "unprognostic (4.42e-2)" "unprognostic (5.64e-2)" "unprognostic (9.02e-2)" "unprognostic (1.25e-1)" "unprognostic (3.09e-1)" "unprognostic (1.28e-3)" "unprognostic (9.43e-2)" "unprognostic (2.58e-1)" "unprognostic (3.40e-2)" "unprognostic (2.26e-2)" "unprognostic (2.47e-1)" "unprognostic (1.50e-1)" "unprognostic (4.04e-1)" "unprognostic (5.08e-3)" "unprognostic (2.60e-1)" "unprognostic (6.28e-2)" 20.4 18.5 25.9 18.0 25.8 55.0 20.5 24.7 36.7 22.4 22.8 21.4 17.3 19.9 26.1 26.9 16.7 16.4 21.8 25.4 24.8 20.3 18.6 20.0 23.7 25.6 25.2 17.0 17.0 27.5 20.8 20.9 25.5 21.6 23.9 16.8 20.8 20.4 22.6 33.7 20.6 23.6 23.4 25.8 19.5 24.3 25.8 35.1 19.0 19.4 29.6 23.0 21.7 25.5 29.2 81.7 43.3 52.4 42.3 42.5 24.0 30.2 62.0 64.9 61.7 37.4 28.1 40.3 27.0 59.4 46.6 38.0 65.9 53.1 74.8 40.8 51.9 33.8 61.2 56.7 35.8 59.8 49.5 21.1 44.1 53.0 58.4 31.4 57.4 52.1 38.8 35.2 51.2 32.0 75.9 52.7 35.5 35.4 31.0 46.2 82.4 40.2 44.3 60.6 37.3 56.0 33.9 18.6 27.3 50.9 44.1 58.3 40.0 50.3 26.9 36.3 45.8 27.5 36.6 44.7 41.2 36.8 41.2 30.2 17.4 20.4 16.0 25.2 14.7 12.2 12.7 15.5 17.0 11.0 10.6 11.5 21.8 11.0 26.1 10.3 12.8 11.4 25.9 25.8 24.7 36.7 25.4 24.8 25.6 25.2 25.5 23.4 25.8 25.5 17.1 6.4 15.0 6.5 18.6 11.9 7.1 12.4 12.0 16.9 16.3 13.0 13.2 7.2 19.2 22.0 18.8 9.1 23.6 13.4 13.7 16.2 19.4 18.3 26.2 17.6 26.7 13.7 10.7 17.7 8.8 14.5 14.8 23.9 14.5 15.3 16.1 14.7 11.1 6.7 10.5 15.3 10.2 14.8 11.5 10.6 12.5 18.4 17.8 14.0 24.8 10.6 21.6 9.5 15.8 21.2 16.0 10.9 20.0 9.4 10.1 12.4 13.7 19.8 19.7 20.3 14.4 27.9 16.8 17.2 13.4 21.2 20.9 11.1 10.8 14.3 DIAPH1 "DFNA1, hDIA1, LFHL1" ENSG00000131504 "Diaphanous related formin 1" O60610 5 141515016-141619055 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hearing Actin-binding "Cancer-related genes, Deafness, Disease variant, Epilepsy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 172.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 564.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004916, HPA076913" Approved Uncertain "Plasma membrane,Cytosol" NA NA 2000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA004916: AB_1847668, HPA076913: " "unprognostic (6.79e-2)" "unprognostic (2.99e-1)" "unprognostic (2.12e-3)" "unprognostic (3.73e-2)" "unprognostic (4.18e-2)" "unprognostic (1.54e-1)" "unprognostic (2.08e-1)" "unprognostic (4.54e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "prognostic unfavorable (7.81e-5)" "unprognostic (2.88e-3)" "prognostic favorable (1.29e-5)" "unprognostic (1.64e-2)" "unprognostic (1.84e-2)" "unprognostic (7.00e-2)" "unprognostic (1.65e-1)" 27.9 20.3 21.0 42.1 22.5 90.2 24.2 18.3 20.9 24.4 40.0 31.0 40.6 18.5 44.3 58.0 25.2 30.0 34.9 21.5 25.7 38.1 91.7 51.3 67.0 18.8 19.9 12.9 37.3 44.6 24.5 25.1 20.1 14.7 31.1 28.4 36.1 19.3 172.0 47.3 36.5 18.7 18.0 36.3 45.1 19.9 27.4 68.5 33.1 55.7 66.4 47.1 30.4 18.6 147.8 92.6 53.2 68.4 40.4 54.5 71.3 59.5 62.2 67.7 70.2 318.1 131.6 156.5 88.1 85.5 103.0 157.9 116.9 191.5 84.8 88.9 66.6 282.6 121.4 103.6 37.7 198.9 564.7 34.4 102.1 94.5 95.5 30.5 87.0 234.8 101.2 106.9 67.7 141.5 217.2 256.8 51.6 75.2 61.6 240.1 87.1 87.6 129.8 158.5 69.4 37.3 146.2 184.6 59.5 47.5 77.5 92.1 52.8 93.9 49.9 52.1 119.9 54.2 94.4 111.7 50.2 153.7 57.8 23.6 12.8 29.8 32.6 14.0 21.2 9.3 20.3 25.3 12.6 9.1 14.8 23.9 13.7 13.7 15.1 10.0 18.7 15.4 21.0 22.5 18.3 20.9 21.5 25.7 18.8 19.9 20.1 18.0 27.4 18.6 33.9 48.1 46.8 11.8 40.0 52.6 60.8 22.4 21.6 17.3 35.1 23.1 18.6 22.8 48.0 44.1 54.2 20.9 96.9 60.5 5.9 62.7 27.9 42.3 18.9 39.0 5.4 52.6 44.1 98.0 31.9 25.9 76.0 83.0 46.9 14.5 16.8 91.6 17.1 6.7 33.6 23.1 12.2 38.4 60.6 9.0 11.8 78.5 19.6 24.4 54.6 12.1 115.4 25.6 9.1 122.9 35.7 10.9 54.1 77.3 35.2 13.9 30.4 69.0 13.1 15.4 26.4 18.3 26.1 38.7 59.7 52.1 92.8 18.3 30.1 91.2 DICER1 "Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1" ENSG00000100697 "Dicer 1, ribonuclease III" Q9UPY3 14 95086228-95158010 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing" "Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 418.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000694, CAB068185" Approved Supported Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB068185: AB_2665650, HPA000694: AB_1078661" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (1.21e-1)" "unprognostic (1.72e-1)" "unprognostic (6.75e-2)" "unprognostic (9.62e-2)" "unprognostic (1.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.21e-1)" "unprognostic (8.52e-3)" "unprognostic (5.73e-2)" "unprognostic (9.22e-2)" "unprognostic (4.22e-2)" "unprognostic (9.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.04e-3)" "unprognostic (3.74e-2)" 15.6 7.9 6.7 14.0 22.5 10.8 15.1 12.3 11.4 13.3 7.4 13.0 7.5 12.7 8.3 15.0 12.4 8.7 9.9 7.2 14.0 10.7 12.8 14.9 11.0 19.1 16.0 14.3 12.6 11.5 10.6 18.7 18.5 12.5 10.9 19.3 12.4 10.1 19.2 13.0 11.6 11.5 11.6 12.1 10.1 13.2 20.3 8.5 14.7 16.2 12.0 12.7 14.5 39.4 18.6 19.4 40.7 12.0 7.2 14.5 26.4 15.5 10.7 11.3 11.1 25.4 12.5 20.9 16.1 16.0 10.4 21.2 31.6 13.9 20.5 35.9 14.6 36.5 10.1 16.0 6.7 22.6 18.0 12.2 10.1 12.3 20.8 8.0 16.1 15.7 15.7 16.6 16.9 21.8 24.1 6.8 9.3 11.0 10.2 16.0 31.9 12.2 8.2 30.9 31.9 16.4 16.2 13.4 15.2 19.2 18.0 12.4 16.4 8.1 14.4 14.0 16.9 18.9 31.7 31.4 8.0 14.5 13.1 1.4 1.1 0.8 0.3 1.4 0.7 0.7 0.6 0.4 0.8 0.7 0.5 0.3 3.9 0.5 3.2 0.4 0.7 0.4 6.7 22.5 12.3 11.4 7.2 14.0 19.1 16.0 18.5 11.6 20.3 39.4 69.4 54.5 53.7 88.8 45.7 27.4 49.5 29.9 40.5 98.2 50.7 29.1 36.4 41.5 47.3 46.0 56.3 46.6 36.9 44.0 5.9 33.4 23.3 37.4 54.2 52.0 46.1 33.4 99.7 23.1 22.8 45.6 33.1 50.1 12.0 35.5 42.1 60.1 48.8 107.7 112.2 29.7 24.4 104.2 24.8 15.5 54.3 82.3 23.2 81.5 84.6 33.5 33.0 109.1 418.6 33.2 28.0 52.6 39.2 62.5 27.1 25.9 38.6 73.8 32.9 64.3 41.9 45.5 56.1 63.0 27.6 25.7 31.7 35.9 33.9 62.1 DIO2 "SelY, TXDI2" ENSG00000211448 "Iodothyronine deiodinase 2" Q92813 14 80197526-80387757 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 163.9;thyroid gland: 355.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 150.7;Endometrial stromal cells: 158.3;Extravillous trophoblasts: 523.3;Muller glia cells: 246.4" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 80.8;fHDF/TERT166: 41.8;HeLa: 95.4;HHSteC: 44.2;SiHa: 168.1;SK-BR-3: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048002 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA048002: AB_2680230" "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.67e-4)" "prognostic favorable (4.62e-6)" "unprognostic (2.76e-1)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.17e-1)" "unprognostic (2.07e-1)" "unprognostic (8.78e-2)" "unprognostic (3.68e-2)" "unprognostic (2.48e-1)" "unprognostic (1.00e-3)" "unprognostic (5.08e-2)" "unprognostic (3.43e-1)" "unprognostic (8.40e-2)" "unprognostic (7.15e-2)" 1.5 3.0 18.0 0.6 15.3 0.1 15.3 15.0 24.6 163.9 5.9 1.3 1.3 40.2 0.5 58.9 0.7 5.1 11.9 17.1 13.0 5.0 0.1 1.6 0.8 13.6 19.2 0.2 1.8 6.6 31.6 14.5 17.4 9.0 1.7 7.4 33.3 30.4 6.5 7.1 1.5 4.5 5.5 0.6 5.3 4.7 13.3 1.2 355.8 70.7 33.1 6.0 25.0 16.6 0.2 9.5 0.0 0.0 0.5 1.4 0.3 80.8 16.6 6.2 0.9 0.0 0.3 0.2 0.2 41.8 0.3 1.7 2.9 0.0 6.1 0.0 0.2 0.0 95.4 0.0 44.2 0.0 0.2 5.1 0.0 1.2 0.0 3.9 1.4 0.0 0.0 0.8 0.5 1.9 0.1 0.1 1.7 0.0 0.5 0.8 3.9 0.1 0.0 0.8 0.0 0.2 168.1 35.3 0.3 7.1 0.1 0.0 0.8 0.3 7.0 17.4 20.1 2.8 0.0 0.0 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 15.3 15.0 24.6 17.1 13.0 13.6 19.2 17.4 5.5 13.3 16.6 0.1 0.0 0.5 52.9 0.3 2.9 0.1 0.0 2.2 3.3 150.7 34.4 1.9 0.0 0.0 0.0 0.0 4.8 0.5 0.2 0.0 0.0 29.5 14.2 158.3 2.3 0.0 0.0 1.0 0.0 523.3 24.6 0.0 15.6 0.0 0.1 0.7 0.2 9.2 1.7 1.0 0.5 0.0 1.3 5.7 12.5 3.4 1.3 5.4 4.7 0.0 246.4 0.0 8.5 1.4 1.0 0.0 4.1 0.3 0.3 0.0 0.0 0.0 7.8 0.0 69.1 6.5 9.7 0.7 8.9 3.0 28.2 1.7 0.9 0.1 0.1 DIPK2A "C3orf58, DIA1, HASF, MGC33365" ENSG00000181744 "Divergent protein kinase domain 2A" Q8NDZ4 3 143971823-144048719 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 23.5;Cardiomyocytes: 19.6;dendritic cells: 11.3;Fibroblasts: 22.6;Hofbauer cells: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 147.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048992 Approved "Secreted in other tissues" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" "HPA048992: AB_2680591" "unprognostic (5.96e-2)" "unprognostic (8.54e-2)" "unprognostic (1.17e-1)" "unprognostic (2.24e-1)" "unprognostic (2.43e-1)" "unprognostic (2.85e-2)" "unprognostic (3.74e-2)" "unprognostic (2.31e-2)" "unprognostic (1.52e-1)" "unprognostic (1.54e-1)" "unprognostic (3.44e-1)" "unprognostic (3.98e-1)" "prognostic unfavorable (2.92e-7)" "unprognostic (4.82e-3)" "unprognostic (2.87e-1)" "unprognostic (1.70e-1)" "unprognostic (1.50e-2)" 9.8 7.4 10.3 10.5 14.5 32.4 15.7 24.5 17.9 13.6 3.8 8.2 6.8 14.2 6.0 14.1 12.7 14.2 7.0 9.1 10.9 6.8 18.9 12.9 11.3 12.6 11.0 20.2 4.5 15.0 3.4 38.1 11.9 11.5 8.8 5.8 9.0 12.6 4.6 24.4 5.9 15.1 9.7 10.7 8.4 8.0 10.6 16.6 12.7 7.2 11.0 11.5 9.7 23.9 24.9 9.9 24.8 147.9 22.6 20.4 13.5 17.7 17.2 16.6 17.6 6.7 9.8 15.5 13.6 6.8 11.9 13.9 37.2 14.3 25.9 7.3 13.5 23.0 9.4 10.1 9.8 21.3 10.3 17.0 7.5 10.2 15.4 16.7 26.1 7.0 4.1 43.9 21.2 6.7 7.7 10.4 15.7 10.3 6.2 11.3 12.8 17.2 10.3 29.1 16.5 0.0 12.7 5.8 5.8 6.7 15.5 11.5 12.5 14.6 7.0 22.9 20.6 17.4 6.5 22.1 23.6 10.0 19.3 24.9 11.9 20.1 3.5 7.8 5.8 8.2 4.2 3.7 14.9 7.1 3.6 3.6 3.3 9.5 10.6 9.3 3.9 6.0 10.3 14.5 24.5 17.9 9.1 10.9 12.6 11.0 11.9 9.7 10.6 23.9 23.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 1.6 11.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.1 22.6 0.0 0.0 0.0 0.0 0.0 0.0 22.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 3.4 2.6 0.0 0.0 0.0 DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Adipocytes: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 57 "HUVEC TERT2: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" 40.8 5.3 14.4 6.1 15.0 0.8 36.9 11.7 13.9 19.6 7.8 9.1 2.6 20.5 6.9 6.5 18.0 8.8 27.3 11.4 13.1 7.0 1.4 14.1 5.7 14.4 14.2 6.9 3.5 4.6 3.3 40.5 14.1 11.3 3.8 1.4 6.8 7.2 16.6 7.4 7.7 20.7 12.4 3.1 6.3 1.5 14.8 2.7 18.5 16.6 3.4 14.3 13.9 15.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 81.7 0.1 0.0 0.5 0.0 0.1 0.0 0.3 0.1 1.4 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.4 15.0 11.7 13.9 11.4 13.1 14.4 14.2 14.1 12.4 14.8 15.4 96.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DIRAS3 "ARHI, NOEY2" ENSG00000162595 "DIRAS family GTPase 3" O95661 1 68045886-68051631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 143.9;ovary: 60.1;pituitary gland: 52.5" "Group enriched" "Detected in many" 5 "Distal tubular cells: 64.6;Theca cells: 206.2" "Group enriched" "Detected in many" 4 "endometrial cancer: 4.3;glioma: 16.3;pancreatic cancer: 5.6;thyroid cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 8.2;HSkMC: 17.2;TIME: 11.2;U-251 MG: 9.1;U-87 MG: 16.9" "Low region specificity" "Detected in all" "HPA028483, HPA028557, HPA029384" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nuclear membrane, Cytosol" "HPA028483: AB_10599599, HPA028557: AB_10602091, HPA029384: AB_10601343" "prognostic favorable (9.21e-4)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (1.69e-2)" "unprognostic (1.15e-2)" "unprognostic (2.84e-1)" "unprognostic (1.58e-1)" "unprognostic (2.31e-2)" "unprognostic (1.13e-1)" "unprognostic (7.86e-2)" "unprognostic (8.35e-2)" "unprognostic (4.33e-1)" "prognostic favorable (9.21e-4)" "unprognostic (1.34e-1)" "unprognostic (4.99e-1)" "unprognostic (1.24e-2)" "unprognostic (5.07e-3)" 1.4 20.1 25.3 0.5 18.7 0.1 5.0 2.2 11.5 5.2 3.0 3.3 7.5 2.5 10.6 1.7 3.3 10.2 11.3 7.0 143.9 6.9 9.5 5.1 0.2 39.6 49.2 60.1 20.0 7.5 52.5 0.6 18.5 2.9 0.8 4.0 2.3 2.6 1.1 2.1 1.4 1.2 7.8 2.5 4.2 5.5 104.7 1.6 3.8 1.9 0.3 3.1 6.4 8.0 0.0 1.5 1.6 0.0 5.2 3.9 0.6 4.6 1.6 0.3 1.2 0.0 0.8 0.0 0.2 4.8 0.1 0.2 0.2 0.0 0.3 0.0 0.2 0.0 0.6 0.0 8.2 0.0 0.0 17.2 0.1 0.7 0.0 0.0 1.0 0.2 0.3 0.0 5.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.2 0.0 0.1 0.5 0.1 0.0 11.2 0.0 0.5 0.2 9.1 2.7 0.0 0.0 16.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 25.3 18.7 2.2 11.5 7.0 143.9 39.6 49.2 18.5 7.8 104.7 8.0 0.3 0.0 1.8 5.2 0.0 3.2 25.0 0.6 0.6 1.1 5.4 6.5 5.9 7.2 2.5 3.7 10.4 1.1 0.0 0.4 64.6 3.7 0.1 0.7 0.7 1.7 16.2 0.0 2.2 18.7 0.1 10.3 4.1 1.8 0.0 0.8 3.3 3.9 0.1 0.0 8.8 2.3 0.0 0.0 4.8 0.8 6.8 0.3 5.4 0.0 0.0 0.7 1.0 5.0 0.2 2.9 0.1 1.5 0.0 5.3 0.1 11.1 0.9 6.1 0.0 16.9 1.7 0.0 1.4 1.7 2.8 0.4 0.7 206.2 0.7 2.4 DISP1 "DISPA, DKFZP434I0428, MGC13130, MGC16796" ENSG00000154309 "Dispatched RND transporter family member 1" Q96F81 1 222815022-223005995 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.7;Gastric mucus-secreting cells: 48.4;Inhibitory neurons: 54.4;Microglial cells: 204.2;Oligodendrocyte precursor cells: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 15.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051411 Uncertain Approved "Nuclear bodies" No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear bodies" "HPA051411: AB_2681475" "unprognostic (2.10e-2)" "unprognostic (3.31e-1)" "unprognostic (7.00e-2)" "unprognostic (7.81e-2)" "unprognostic (7.82e-2)" "unprognostic (2.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.27e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-1)" "prognostic favorable (5.00e-4)" "unprognostic (4.13e-1)" "prognostic favorable (3.86e-5)" "unprognostic (5.24e-2)" "unprognostic (2.38e-1)" "prognostic favorable (4.16e-4)" "unprognostic (9.69e-3)" 6.8 5.7 1.7 1.5 2.0 0.2 3.0 4.0 2.5 3.2 3.7 9.0 2.6 4.3 2.0 1.9 2.4 4.6 3.9 1.6 1.9 5.2 2.7 9.2 1.1 1.2 0.9 4.5 2.4 5.1 2.5 4.6 1.1 2.4 2.1 1.3 1.9 2.0 4.1 3.3 3.7 4.2 0.7 2.5 5.3 6.5 1.5 1.4 5.2 3.1 1.4 5.4 2.5 2.6 0.9 2.2 5.6 3.8 10.1 6.1 2.4 3.2 2.7 1.1 1.1 2.6 1.6 0.1 4.2 1.5 2.2 0.6 1.6 1.3 1.6 8.1 2.4 1.1 6.3 1.2 4.4 0.2 1.1 4.8 1.9 2.3 0.9 5.8 2.3 1.2 0.0 0.1 3.9 1.5 1.4 0.3 4.0 6.1 1.3 1.7 15.1 0.2 6.8 0.8 1.6 2.5 1.8 0.7 2.3 2.7 2.7 1.4 4.2 2.3 1.5 3.9 3.6 1.2 0.5 0.3 3.2 0.8 5.1 0.3 0.2 0.0 0.7 0.4 1.6 0.5 0.6 0.7 0.6 0.9 0.6 0.5 0.1 1.0 0.2 0.3 0.5 0.4 1.7 2.0 4.0 2.5 1.6 1.9 1.2 0.9 1.1 0.7 1.5 2.6 4.6 6.4 1.7 42.7 3.6 0.5 0.6 1.2 5.7 2.7 3.4 1.5 7.8 7.2 3.3 11.0 0.0 1.4 2.1 1.0 0.0 1.9 2.1 1.9 3.4 4.9 0.0 0.0 47.7 2.8 1.8 5.6 48.4 4.1 0.0 15.8 6.8 3.3 5.9 0.0 54.4 2.6 4.1 1.6 0.9 3.7 1.5 4.1 0.0 204.2 1.4 0.9 5.2 199.6 15.4 1.3 3.1 3.4 0.7 0.7 6.4 5.8 2.7 2.3 0.0 4.0 3.7 2.1 2.3 5.4 1.1 0.8 1.7 2.8 1.6 0.3 DIXDC1 "Dixin, KIAA1735" ENSG00000150764 "DIX domain containing 1" Q155Q3 11 111927144-112022653 "Predicted intracellular proteins" "Wnt signaling pathway" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 104.3;Horizontal cells: 121.1;Oligodendrocytes: 140.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "eosinophil: 5.2" "Lineage enriched" "Detected in single" 11 "granulocytes: 5.2" "Cell line enhanced" "Detected in many" "hTERT-HME1: 42.7;TIME: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039424, HPA039658, HPA061366" Approved Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA039424: AB_2676500, HPA039658: AB_2676611, HPA061366: " "unprognostic (1.93e-1)" "unprognostic (2.90e-2)" "unprognostic (8.93e-3)" "unprognostic (2.84e-1)" "unprognostic (2.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.37e-1)" "unprognostic (1.41e-1)" "unprognostic (7.23e-2)" "unprognostic (1.59e-1)" "unprognostic (7.85e-2)" "unprognostic (5.11e-2)" "prognostic favorable (6.89e-5)" "unprognostic (4.10e-2)" "unprognostic (2.11e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (4.19e-5)" 17.8 17.7 16.4 8.6 23.2 0.7 15.0 36.8 22.6 18.7 22.8 29.5 5.6 24.8 18.6 12.7 20.4 12.6 23.3 17.0 16.9 11.4 7.0 9.4 2.6 20.1 21.8 15.8 3.8 17.1 7.1 10.8 19.1 23.4 10.0 22.0 7.8 35.8 13.7 5.4 9.1 25.6 18.0 2.9 14.9 19.1 19.7 2.6 10.7 12.3 2.5 25.3 12.0 34.4 0.8 3.7 9.9 18.5 29.9 17.5 2.1 7.7 5.3 2.9 5.2 0.6 2.0 1.6 2.0 21.5 3.4 0.9 4.4 2.4 2.9 6.4 3.7 0.8 5.8 10.3 4.6 5.3 0.7 14.2 19.3 6.3 42.7 21.5 30.6 4.0 5.2 0.6 11.9 0.9 3.3 4.6 5.9 0.8 6.6 1.6 2.9 6.1 12.1 0.3 8.0 16.7 5.7 4.6 2.5 4.3 6.8 2.0 50.4 13.1 5.6 2.4 12.9 1.2 5.5 0.8 7.2 13.5 4.7 0.0 0.1 5.2 0.3 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.1 16.4 23.2 36.8 22.6 17.0 16.9 20.1 21.8 19.1 18.0 19.7 34.4 12.8 16.0 10.3 40.1 0.4 6.4 16.3 4.1 11.4 22.3 23.7 28.8 35.6 7.2 10.1 18.4 104.3 1.4 0.9 2.6 15.6 6.4 23.1 32.1 48.6 28.1 2.4 2.1 47.7 7.7 5.1 32.8 11.7 11.3 1.3 6.3 62.8 19.3 1.7 121.1 83.8 13.9 6.1 3.4 5.3 17.5 39.7 1.5 12.4 20.6 1.0 30.2 0.0 34.7 140.4 7.0 6.2 36.9 2.0 10.8 2.7 15.4 35.5 69.2 13.1 25.3 31.8 62.3 16.4 3.3 4.1 1.4 2.0 3.5 4.5 3.1 DKK1 "DKK-1, SK" ENSG00000107984 "Dickkopf WNT signaling pathway inhibitor 1" O94907 10 52314281-52318042 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 34.0;placenta: 48.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 486.2;Endometrial stromal cells: 337.6;Pancreatic endocrine cells: 194.6;Prostatic glandular cells: 992.9;Urothelial cells: 320.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 1141.1;BJ hTERT+: 620.0;CACO-2: 1011.3;fHDF/TERT166: 1590.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in other tissues" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.65e-2)" "unprognostic (4.21e-2)" "unprognostic (7.09e-2)" "unprognostic (7.99e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.35e-8)" "unprognostic (7.93e-2)" "prognostic unfavorable (7.80e-6)" "unprognostic (1.54e-1)" "unprognostic (6.87e-2)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.81e-1)" "unprognostic (1.68e-1)" "unprognostic (7.47e-3)" "unprognostic (4.05e-1)" "unprognostic (1.19e-1)" "unprognostic (2.06e-2)" 22.0 0.3 0.6 0.3 0.8 0.0 5.6 1.1 0.9 34.0 0.4 0.3 0.1 1.8 0.0 7.9 0.4 3.9 0.7 0.5 1.5 0.6 0.2 1.2 0.4 0.6 1.6 1.0 0.2 0.1 0.1 48.9 0.8 4.8 0.1 7.0 2.3 1.9 0.3 16.5 0.2 0.2 0.7 0.8 1.2 0.2 1.7 0.0 0.3 0.0 0.5 21.9 10.6 0.6 315.3 215.8 0.1 32.4 149.6 30.4 0.1 1141.1 620.0 383.8 202.5 1011.3 64.2 0.0 1.6 1590.5 93.5 245.1 0.3 130.7 361.3 0.1 0.7 0.0 4.4 26.2 31.8 0.0 0.1 30.3 16.0 83.0 488.3 19.8 35.8 0.0 0.0 0.1 255.8 135.7 0.0 0.1 0.2 13.7 543.9 0.2 34.8 0.0 148.6 25.6 0.2 342.4 102.8 1.1 17.7 0.4 1.1 0.9 78.9 0.2 0.2 338.5 211.9 0.1 0.3 0.1 4.6 0.1 37.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.1 0.9 0.5 1.5 0.6 1.6 0.8 0.7 1.7 0.6 1.9 25.6 0.0 0.0 1.0 5.4 486.2 28.5 0.0 0.2 0.8 6.9 1.1 0.0 15.2 0.0 0.0 4.6 0.0 0.9 0.0 10.7 1.2 11.0 337.6 8.5 0.0 0.0 1.2 4.1 4.0 91.5 2.6 8.1 4.5 0.0 1.1 0.0 9.3 0.0 2.2 2.4 6.1 0.0 1.6 0.6 0.0 4.9 0.0 1.0 0.0 6.1 0.0 1.5 0.2 194.6 5.0 0.0 1.3 992.9 0.4 0.0 9.8 0.4 0.0 0.0 10.6 0.4 2.2 1.4 3.1 8.3 2.8 0.0 1.0 320.0 DKK2 ENSG00000155011 "Dickkopf WNT signaling pathway inhibitor 2" Q9UBU2 4 106921802-107283806 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 15.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.6;Fibroblasts: 18.7;Hofbauer cells: 16.8;Inhibitory neurons: 32.5;Langerhans cells: 11.8;Suprabasal keratinocytes: 7.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 22.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "cerebral cortex: 1.5;midbrain: 5.0;pons: 6.3;thalamus: 5.7" "CAB009727, HPA052611" Uncertain Supported "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "CAB009727: AB_2091492, HPA052611: AB_2732576" "unprognostic (3.14e-3)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (3.21e-2)" "unprognostic (9.75e-2)" "unprognostic (3.68e-1)" "unprognostic (1.04e-3)" "unprognostic (2.47e-2)" "unprognostic (5.11e-1)" "unprognostic (5.21e-2)" "unprognostic (3.21e-1)" "unprognostic (3.52e-1)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (6.86e-2)" "unprognostic (3.22e-1)" "unprognostic (4.58e-2)" 1.4 0.8 0.4 0.4 1.4 0.0 3.0 0.0 1.5 15.2 1.2 1.7 0.0 1.0 0.4 1.2 0.5 0.7 2.2 0.7 0.6 0.2 0.2 5.3 0.7 0.9 4.5 4.4 0.2 0.6 1.5 2.8 0.3 2.3 0.5 0.4 1.3 1.7 1.9 4.7 0.3 0.6 0.2 1.3 0.1 0.1 2.3 1.0 0.9 1.2 3.0 0.2 0.8 0.8 0.0 0.0 3.6 0.0 0.6 0.3 0.0 0.1 0.3 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 1.0 0.4 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 1.5 0.7 0.6 0.9 4.5 0.3 0.2 2.3 0.8 2.6 0.0 0.0 0.3 0.0 7.6 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 1.1 5.4 0.0 0.0 5.2 0.0 0.2 18.7 0.0 0.1 0.0 0.0 3.3 0.0 16.8 0.0 32.5 0.0 0.0 0.3 11.8 0.0 4.1 0.3 7.2 2.8 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 7.4 0.0 0.8 2.0 0.0 0.0 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DKK4 ENSG00000104371 "Dickkopf WNT signaling pathway inhibitor 4" Q9UBT3 8 42374063-42377229 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.7;esophagus: 4.9" "Group enriched" "Detected in some" 5 "Basal prostatic cells: 5.2;Early spermatids: 2.1;Pancreatic endocrine cells: 4.4;Prostatic glandular cells: 3.7;Spermatocytes: 2.2;Urothelial cells: 5.3" "Cancer enriched" "Detected in many" 20 "endometrial cancer: 174.4" "Group enriched" "Detected in some" 4 "cerebellum: 3.7;midbrain: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "OE19: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA052916 Uncertain "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA052916: AB_2681987" "unprognostic (1.64e-1)" "unprognostic (5.84e-2)" "unprognostic (1.97e-1)" "unprognostic (5.37e-3)" "unprognostic (3.23e-1)" "unprognostic (2.91e-2)" "unprognostic (2.13e-2)" "unprognostic (1.99e-1)" "unprognostic (6.80e-2)" "unprognostic (2.71e-2)" "unprognostic (1.63e-2)" "unprognostic (6.73e-2)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (8.11e-2)" 0.2 0.0 0.0 0.0 0.0 0.1 0.8 3.7 0.1 1.0 0.0 0.0 2.4 0.0 0.7 4.9 0.3 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.7 3.1 0.0 0.0 0.0 0.9 0.0 0.6 0.1 0.0 0.1 0.9 0.1 0.1 0.1 0.4 0.3 0.0 0.0 0.8 1.4 0.5 0.3 0.0 0.0 0.4 1.1 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.1 0.7 3.1 0.6 0.0 0.5 0.1 0.6 0.0 0.0 0.0 0.0 0.3 5.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.1 0.3 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.4 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.2 0.1 0.4 0.0 0.0 0.0 0.0 0.1 5.3 DKKL1 "CT34, SGY-1" ENSG00000104901 "Dickkopf like acrosomal protein 1" Q9UK85 19 49361783-49375116 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 277 "testis: 344.8" "Group enriched" "Detected in some" 4 "Early spermatids: 2188.8;Late spermatids: 2340.4" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 17 "B-cells: 1.7" "Cell line enhanced" "Detected in some" "AF22: 5.1;AN3-CA: 9.8;HeLa: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025410, HPA047194" Enhanced Approved Vesicles "Secreted in male reproductive system" NA NA "Cluster 37: B-cells - Transcription" "Cluster 36: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB025410: , HPA047194: AB_2679979" "unprognostic (1.64e-1)" "unprognostic (5.30e-1)" "unprognostic (5.39e-4)" "unprognostic (1.85e-4)" "unprognostic (3.79e-2)" "unprognostic (4.30e-2)" "unprognostic (5.52e-4)" "unprognostic (1.00e-1)" "unprognostic (6.76e-2)" "unprognostic (4.08e-1)" "unprognostic (1.90e-1)" "unprognostic (5.65e-2)" "unprognostic (2.56e-3)" "unprognostic (1.36e-1)" "unprognostic (1.13e-1)" "unprognostic (1.18e-1)" "unprognostic (5.57e-2)" 0.7 0.5 0.3 0.5 0.3 0.0 0.5 0.2 0.5 0.7 0.4 0.5 0.3 1.1 0.3 0.2 1.2 0.7 0.4 0.2 0.1 0.6 0.3 0.3 0.5 0.4 0.3 0.8 1.0 0.1 0.1 0.3 0.2 0.6 0.1 0.3 0.9 0.6 0.2 0.2 0.3 0.4 0.3 0.4 0.3 344.8 0.2 0.0 0.2 0.4 0.2 0.4 0.4 0.3 0.0 1.2 5.1 9.8 0.0 0.3 0.4 0.9 0.0 0.1 0.3 0.0 0.5 0.0 0.7 0.1 0.4 0.0 0.1 0.0 0.0 0.0 1.7 0.0 2.9 0.2 0.0 0.0 0.9 0.7 0.3 0.2 0.3 0.9 0.8 0.0 1.2 0.3 0.1 0.4 0.0 0.0 2.0 0.5 1.1 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.9 0.0 0.5 1.0 1.0 2.0 1.2 1.0 0.6 0.6 0.0 0.4 0.6 0.2 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.5 0.2 0.1 0.4 0.3 0.2 0.3 0.2 0.3 1.3 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.6 0.6 1.2 2.2 0.4 0.0 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.4 2188.8 0.5 1.0 1.9 0.0 0.0 0.2 0.5 0.2 0.7 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 2340.4 16.8 1.4 1.8 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 12.0 0.0 0.2 0.0 0.0 0.0 0.4 6.6 0.7 0.9 491.0 15.2 0.2 0.0 0.0 0.1 0.5 0.2 0.2 DLAT "DLTA, E2, PDC-E2" ENSG00000150768 "Dihydrolipoamide S-acetyltransferase" P10515 11 112025408-112064404 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 89.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 100.5;Distal tubular cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003782, HPA040786, HPA062766" Supported Supported Mitochondria NA NA 44000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB003782: , HPA040786: AB_2677136, HPA062766: AB_2684864" "unprognostic (4.57e-3)" "unprognostic (1.75e-1)" "prognostic favorable (6.19e-6)" "unprognostic (7.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.70e-2)" "prognostic unfavorable (7.49e-5)" "unprognostic (8.68e-2)" "unprognostic (5.36e-2)" "unprognostic (2.93e-1)" "unprognostic (2.23e-3)" "unprognostic (6.25e-2)" "prognostic favorable (1.95e-14)" "unprognostic (5.82e-2)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (6.15e-2)" 24.7 16.5 7.7 13.3 8.3 7.9 14.5 9.5 9.3 11.0 10.4 24.7 18.3 10.0 13.4 19.5 13.0 8.5 69.4 8.1 11.1 33.8 15.5 11.7 16.1 8.3 8.9 9.5 6.8 31.7 8.5 13.1 9.7 14.5 26.0 10.8 16.8 14.8 75.4 10.3 16.5 13.4 8.2 9.9 14.3 9.9 9.4 12.7 20.2 89.4 18.2 14.2 8.1 8.0 18.7 16.4 28.2 34.4 41.6 30.5 26.5 26.6 18.2 34.8 38.7 52.8 56.7 85.4 46.0 28.7 42.6 41.0 65.7 34.2 38.9 27.3 30.2 51.9 17.9 39.2 29.0 64.9 26.6 36.9 37.7 32.0 35.2 24.2 33.9 41.7 88.4 42.6 41.2 16.6 25.4 66.9 30.3 58.6 35.4 45.4 38.0 93.3 64.4 21.4 51.2 27.8 30.7 93.4 20.5 30.9 67.4 42.9 17.8 29.1 29.1 29.1 33.0 11.1 19.4 127.5 7.7 73.0 22.7 9.1 3.8 3.0 4.3 5.8 5.4 5.6 4.9 5.1 5.8 4.0 5.6 5.1 0.3 4.7 6.1 4.5 5.8 5.0 7.7 8.3 9.5 9.3 8.1 11.1 8.3 8.9 9.7 8.2 9.4 8.0 7.6 12.8 14.5 15.3 13.8 11.2 9.2 18.2 14.2 8.1 9.2 5.8 100.5 15.7 13.2 11.0 0.0 21.2 6.4 26.3 74.3 18.7 3.9 15.8 11.6 9.6 17.3 18.1 18.0 11.4 39.6 11.7 11.7 12.1 3.8 13.5 7.5 15.5 18.7 8.4 24.4 17.8 24.4 8.8 7.5 3.2 6.2 9.5 17.8 9.4 16.7 10.4 4.1 11.1 19.7 14.1 9.2 10.9 19.4 7.0 19.0 37.6 30.3 11.1 0.0 14.2 19.9 25.1 18.3 21.1 9.8 17.4 8.5 26.3 26.7 9.3 DLK1 "Delta1, FA1, pG2, Pref-1, ZOG" ENSG00000185559 "Delta like non-canonical Notch ligand 1" P80370 14 100725705-100738224 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 1330.8;pituitary gland: 772.9;placenta: 1631.2" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 576.5;Fibroblasts: 699.3;Leydig cells: 1357.0;Skeletal myocytes: 2360.1" "Cancer enhanced" "Detected in many" "liver cancer: 28.1;testis cancer: 25.4" "Region enhanced" "Detected in many" "hypothalamus: 163.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 120.0;Hep G2: 419.1;SH-SY5Y: 473.8" "Region enhanced" "Detected in many" "hypothalamus: 111.7" "Group enriched" "Detected in many" 5 "hypothalamus: 41.2;midbrain: 156.8" "CAB005872, HPA062262" Enhanced Approved "Golgi apparatus" NA NA 2600000 "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "CAB005872: AB_731965, HPA062262: AB_2684729" "unprognostic (2.16e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.49e-1)" "unprognostic (1.14e-1)" "unprognostic (4.89e-3)" "unprognostic (5.75e-2)" "unprognostic (1.87e-2)" "unprognostic (1.12e-1)" "unprognostic (5.24e-1)" "unprognostic (3.11e-2)" "unprognostic (6.57e-2)" 3.1 1330.8 3.4 6.1 1.9 0.1 7.1 0.0 0.8 9.4 0.3 0.2 1.8 0.7 0.2 2.6 3.1 2.2 45.7 0.5 163.3 0.6 1.8 0.8 0.5 15.4 38.7 277.2 21.2 0.0 772.9 1631.2 81.7 1.4 0.0 0.0 26.9 0.0 17.5 1.2 1.3 0.2 2.1 1.1 1.0 40.9 14.7 1.7 0.2 83.1 0.0 1.0 1.5 0.9 0.0 0.0 120.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 12.6 0.3 419.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 60.6 0.0 0.0 0.0 0.0 0.3 3.4 0.0 0.0 0.0 1.4 0.1 0.0 0.5 33.7 473.8 0.0 0.1 0.0 2.9 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.4 1.9 0.0 0.8 0.5 163.3 15.4 38.7 81.7 2.1 14.7 0.9 0.4 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 1.3 1.0 2.6 0.0 0.0 0.0 0.0 55.2 0.2 0.0 0.0 4.8 7.1 0.0 0.0 6.7 0.0 0.0 0.0 576.5 45.3 699.3 0.0 0.0 0.0 0.8 0.0 0.0 84.3 0.0 0.0 0.0 0.0 0.0 0.3 35.0 1357.0 4.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.0 0.0 172.6 0.0 1.3 0.0 0.2 0.0 0.0 59.2 2360.1 3.0 13.5 69.9 0.0 0.4 105.8 0.8 63.2 0.0 0.2 DLL1 ENSG00000198719 "Delta like canonical Notch ligand 1" O00548 6 170282206-170306565 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 53.9" "Cell type enhanced" "Detected in many" "Adipocytes: 88.8;Basal keratinocytes: 66.9;Basal squamous epithelial cells: 82.0;Enteroendocrine cells: 51.9;Intestinal goblet cells: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 3.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 3.3" "Cell line enhanced" "Detected in some" "HaCaT: 6.8;HBEC3-KT: 4.5;NB-4: 14.2;THP-1: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001255 Approved "Plasma membrane" NA NA 690000 "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "HPA001255: " "unprognostic (1.03e-1)" "unprognostic (9.22e-2)" "unprognostic (2.17e-3)" "unprognostic (1.95e-1)" "unprognostic (2.89e-2)" "unprognostic (6.35e-2)" "unprognostic (1.63e-2)" "unprognostic (1.89e-1)" "unprognostic (9.22e-2)" "unprognostic (1.14e-2)" "unprognostic (1.39e-2)" "unprognostic (2.64e-2)" "unprognostic (5.23e-3)" "unprognostic (3.50e-1)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.66e-1)" 20.9 8.6 2.8 2.1 6.9 0.7 19.2 3.3 4.5 21.1 0.2 15.4 3.9 10.1 0.3 21.9 11.5 0.8 15.9 2.2 2.9 12.5 6.4 13.1 1.9 6.0 5.1 4.2 16.9 0.3 6.2 1.2 4.8 28.7 0.9 0.4 17.7 1.1 5.3 26.2 19.3 0.8 2.0 53.9 10.9 1.6 4.0 0.2 12.4 0.7 0.4 9.6 22.9 11.0 0.7 0.1 3.3 2.0 0.1 0.1 1.5 0.3 0.2 0.2 0.3 1.0 0.1 0.0 0.3 0.1 0.6 6.8 1.4 4.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.6 0.0 0.4 0.1 0.7 0.0 0.0 0.0 0.1 0.8 0.0 14.2 0.2 0.1 0.0 1.1 2.8 0.0 0.0 0.4 1.6 0.2 0.1 0.0 0.0 1.1 0.4 14.8 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.4 0.0 0.0 0.1 2.8 6.9 3.3 4.5 2.2 2.9 6.0 5.1 4.8 2.0 4.0 11.0 88.8 0.0 0.5 26.1 2.7 66.9 14.9 31.2 82.0 1.4 5.4 14.7 11.8 0.0 7.2 1.8 22.9 3.1 3.0 3.0 0.0 0.3 0.4 5.1 10.1 28.5 51.9 0.4 6.9 1.8 5.9 19.2 1.5 5.3 5.7 0.2 21.4 0.2 1.3 0.0 6.4 80.3 16.2 4.8 6.6 1.9 0.3 2.7 7.2 4.7 0.2 1.1 0.0 28.6 26.7 0.7 2.5 1.2 0.3 4.8 2.5 0.1 9.0 0.6 13.1 12.3 8.2 0.5 2.0 8.5 12.8 3.7 4.7 0.1 3.6 1.1 DLL3 SCDO1 ENSG00000090932 "Delta like canonical Notch ligand 3" Q9NYJ7 19 39498895-39508481 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.7;choroid plexus: 2.3;pituitary gland: 3.4;testis: 1.4" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 24.6;Spermatogonia: 39.5" "Group enriched" "Detected in many" 11 "glioma: 29.2;melanoma: 15.5;testis cancer: 8.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.6;naive CD8 T-cell: 1.4" "Group enriched" "Detected in many" 13 "B-cells: 2.6;T-cells: 1.4" "Cell line enriched" "Detected in some" 6 "SK-MEL-30: 83.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024559, HPA056533" Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA024559: , HPA056533: " "unprognostic (2.52e-1)" "unprognostic (3.81e-1)" "unprognostic (3.13e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.85e-2)" "unprognostic (1.41e-2)" "unprognostic (1.65e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (6.58e-2)" "unprognostic (1.06e-2)" "unprognostic (4.20e-2)" "unprognostic (3.82e-4)" "unprognostic (4.94e-2)" "unprognostic (5.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.97e-1)" 0.0 0.0 5.1 0.1 5.7 0.0 0.0 3.1 5.6 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 4.7 0.0 0.0 0.0 0.1 4.9 4.7 0.2 0.0 0.5 3.4 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.1 0.0 1.4 4.6 0.0 0.1 0.0 0.1 0.0 0.0 5.4 0.1 3.9 0.9 2.0 0.0 0.0 0.6 1.1 0.0 0.7 0.2 0.5 0.9 0.1 3.7 0.0 1.5 0.1 2.3 1.0 0.2 1.2 6.0 0.2 0.1 0.3 0.3 1.0 4.6 0.0 0.0 0.1 0.1 0.1 0.1 4.3 1.1 0.1 0.3 0.0 0.2 0.0 0.7 0.0 6.2 0.6 0.2 0.2 0.2 0.2 13.6 14.1 2.9 0.1 83.7 0.3 0.0 0.2 0.0 0.0 2.6 0.1 1.0 1.4 0.0 0.9 0.1 0.5 2.3 0.0 0.0 0.0 0.3 0.0 0.1 2.6 0.1 0.5 0.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 5.1 5.7 3.1 5.6 4.7 4.7 4.9 4.7 4.2 4.4 4.6 5.4 0.3 0.0 0.0 0.3 1.1 0.3 0.3 0.4 0.0 0.5 1.3 4.7 0.5 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.7 0.6 0.1 0.7 0.2 3.0 0.0 1.7 0.6 0.6 1.0 0.5 0.3 0.0 1.7 0.0 0.0 0.3 0.0 3.4 0.3 0.0 0.0 0.0 2.2 1.2 0.1 1.8 0.0 0.0 0.9 0.0 24.6 0.5 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.7 6.6 0.0 0.6 6.5 39.5 0.2 0.1 0.3 0.5 1.7 0.0 0.1 DMBT1 "Gp-340, GP340, hensin, muclin, SALSA, vomeroglandin" ENSG00000187908 "Deleted in malignant brain tumors 1" Q9UGM3 10 122560665-122643736 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense, Differentiation, Host-virus interaction, Protein transport, Transport" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 19 "intestine: 1651.4;salivary gland: 519.1" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 192.9;Intestinal goblet cells: 113.4;Paneth cells: 388.2;Proximal enterocytes: 167.8;Undifferentiated cells: 314.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 47.6;stomach cancer: 76.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-HME1: 9.9;LHCN-M2: 16.4;RH-30: 40.3" "Not detected" "Not detected" HPA040778 Enhanced Approved "Centriolar satellite" "Secreted in other tissues" NA NA 5200000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 45: Enterocytes - Digestion" "Centriolar satellite" "HPA040778: AB_2677132" "unprognostic (3.32e-2)" "unprognostic (2.17e-2)" "unprognostic (3.47e-2)" "prognostic favorable (1.43e-4)" "unprognostic (8.77e-2)" "unprognostic (2.56e-2)" "unprognostic (3.70e-1)" "unprognostic (7.97e-2)" "unprognostic (1.31e-1)" "unprognostic (4.51e-1)" "unprognostic (2.22e-1)" "unprognostic (2.20e-1)" "unprognostic (1.08e-9)" "unprognostic (2.26e-1)" "unprognostic (2.92e-4)" "unprognostic (2.00e-3)" "unprognostic (2.22e-1)" 0.5 0.2 0.6 45.3 2.9 0.1 0.3 4.4 1.5 12.8 0.0 55.6 1651.4 1.7 0.0 1.6 3.9 45.7 0.1 0.5 2.3 0.1 0.1 58.4 1.0 6.1 5.2 0.1 1.8 0.0 0.2 0.0 7.2 1.7 17.0 0.0 519.1 0.0 0.3 0.1 518.7 15.3 2.3 0.0 3.8 1.5 4.2 0.1 0.0 0.2 0.2 15.4 0.0 7.8 0.2 0.2 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.5 0.2 1.1 0.0 0.4 0.0 0.2 0.0 0.0 3.2 0.5 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.0 1.3 0.5 9.9 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 2.6 0.2 0.0 0.0 0.0 40.3 6.0 0.0 0.0 0.1 3.0 0.3 0.0 0.1 0.0 0.0 0.0 1.7 0.1 0.8 0.5 2.3 5.7 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.9 4.4 1.5 0.5 2.3 6.1 5.2 7.2 2.3 4.2 7.8 0.0 6.4 192.9 0.7 1.1 0.0 7.0 0.4 0.0 0.0 1.5 0.9 0.7 0.0 3.8 0.0 0.0 0.0 0.0 52.4 0.0 2.1 2.9 1.1 0.2 7.3 0.0 0.0 0.0 15.1 0.0 0.4 0.0 3.5 10.1 0.0 0.0 0.0 0.0 0.0 0.1 113.4 0.0 0.0 0.0 2.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.7 388.2 0.0 0.0 1.7 167.8 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.8 0.0 0.0 0.0 1.8 0.0 314.4 20.3 DMD "BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85" ENSG00000198947 Dystrophin P11532 X 31097677-33339609 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Actin-binding "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 452.8;Excitatory neurons: 1275.8;Inhibitory neurons: 719.8;Oligodendrocyte precursor cells: 1161.6;Oligodendrocytes: 610.2;Rod photoreceptor cells: 375.9" "Cancer enhanced" "Detected in many" "testis cancer: 8.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 7 "B-cells: 1.1;granulocytes: 4.3" "Cell line enhanced" "Detected in many" "AF22: 27.9;Hep G2: 30.3;RH-30: 25.0;SuSa: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000119, HPA002725, HPA023885" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB000119: , HPA002725: AB_1078714, HPA023885: AB_1847931" "unprognostic (3.91e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-2)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (7.58e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-4)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (5.84e-3)" "unprognostic (2.38e-1)" "unprognostic (1.15e-2)" "unprognostic (8.76e-3)" "unprognostic (1.82e-1)" "unprognostic (9.83e-2)" "unprognostic (1.51e-2)" 16.3 14.7 11.8 5.3 12.5 0.6 16.8 0.2 14.2 7.1 7.1 38.0 5.4 18.1 11.2 9.1 16.8 21.5 37.8 15.5 0.5 5.4 50.0 7.2 4.7 1.1 0.6 13.9 52.9 4.3 4.4 15.1 0.4 13.4 8.4 80.0 30.2 30.7 73.4 11.5 9.4 22.0 0.0 2.3 15.5 8.3 4.8 3.3 7.3 67.4 6.4 21.1 7.2 9.9 0.3 0.2 27.9 0.3 0.3 0.3 7.6 6.1 0.6 2.8 3.1 13.3 0.6 0.4 0.2 12.5 2.3 8.5 10.5 15.0 4.2 7.4 8.6 3.3 10.5 30.3 14.7 1.2 3.7 3.3 9.5 4.6 17.1 15.3 6.1 2.0 2.9 0.4 8.3 0.5 4.4 0.6 13.3 0.1 9.8 0.3 25.0 0.1 0.3 3.3 0.5 8.5 0.1 2.3 2.8 27.7 2.2 0.1 1.6 0.3 0.5 1.1 4.6 0.4 23.8 0.6 1.0 2.3 14.4 0.8 0.1 2.0 0.1 0.1 0.1 1.1 0.1 0.1 0.3 0.9 0.1 0.1 4.3 0.1 0.1 0.4 0.2 0.1 11.8 12.5 0.2 14.2 15.5 0.5 1.1 0.6 0.4 0.0 4.8 9.9 8.5 28.9 25.3 164.9 6.7 20.1 7.0 6.3 3.4 78.0 26.5 50.0 452.8 7.2 15.0 3.7 308.6 33.7 0.7 0.8 3.9 3.8 22.4 22.5 1.4 9.9 8.4 0.0 1275.8 12.3 9.5 26.1 3.6 5.6 1.3 37.9 6.1 49.8 4.2 11.8 719.8 1.3 6.1 4.8 5.4 20.5 89.2 3.5 19.6 94.6 6.7 54.9 0.0 1161.6 610.2 6.0 0.1 118.8 0.2 3.6 3.6 2.1 60.4 375.9 118.3 95.2 50.3 4.0 8.8 1.8 11.5 5.1 1.0 33.1 4.2 4.8 DMKN ZD52F10 ENSG00000161249 Dermokine Q6E0U4 19 35497220-35513658 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "skin 1: 4799.0" "Cell type enriched" "Detected in many" 5 "Suprabasal keratinocytes: 8514.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.7" "Group enriched" "Detected in many" 5 "NK-cells: 11.7;T-cells: 6.4" "Cell line enhanced" "Detected in many" "A-431: 150.1;CACO-2: 182.0;CAPAN-2: 153.9;HBEC3-KT: 236.4;RPTEC TERT1: 232.2" "Region enhanced" "Detected in all" "basal ganglia: 51.9" "Low region specificity" "Detected in all" HPA029406 Enhanced Approved Nucleoplasm,Cytosol "Secreted in other tissues" NA NA 47000000 "Cluster 22: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" "HPA029406: AB_10603661" "unprognostic (5.70e-2)" "unprognostic (2.36e-2)" "unprognostic (3.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-2)" "unprognostic (3.82e-2)" "unprognostic (3.23e-1)" "unprognostic (1.03e-1)" "unprognostic (8.82e-2)" "unprognostic (2.54e-1)" "unprognostic (9.93e-2)" "prognostic favorable (5.37e-6)" "unprognostic (3.50e-1)" "unprognostic (1.58e-1)" "unprognostic (1.29e-1)" "unprognostic (2.08e-1)" 13.8 9.3 6.5 1.1 11.7 1.7 195.4 7.3 7.0 262.7 16.1 11.0 5.6 16.1 14.4 221.3 73.9 1.8 11.9 5.9 7.0 50.3 4.7 22.3 1.2 18.4 7.2 35.0 59.7 87.1 58.1 2.2 17.8 19.3 4.9 1.9 69.5 14.6 20.1 4799.0 8.4 4.2 6.6 2.9 19.9 4.1 6.6 12.2 60.0 0.2 50.6 14.1 378.5 6.2 150.1 24.0 0.0 0.1 5.7 8.7 40.5 0.5 19.6 1.0 1.4 182.0 153.9 0.0 57.5 1.4 7.3 81.8 44.5 236.4 1.9 0.7 43.0 0.0 0.0 41.3 6.8 0.0 0.5 77.6 62.3 4.2 133.2 13.4 0.0 0.0 0.8 0.2 0.5 130.2 0.1 0.0 129.2 107.9 9.7 0.2 0.0 6.2 232.2 97.4 0.4 0.0 35.6 0.1 14.9 36.7 58.5 0.0 0.3 22.3 67.1 0.8 0.6 0.9 0.3 1.1 18.8 0.3 1.4 0.0 0.0 0.0 6.4 0.0 5.5 1.7 0.5 3.1 0.0 0.1 0.1 2.0 0.0 11.7 0.0 0.2 0.0 1.3 6.5 11.7 7.3 7.0 5.9 7.0 18.4 7.2 17.8 6.6 6.6 6.2 13.9 105.8 115.3 1.0 5.9 1623.7 143.2 169.9 39.3 1.7 71.8 164.3 20.4 100.1 107.6 204.1 0.0 1.0 6.7 6.0 230.9 138.0 15.9 181.5 9.0 27.7 49.3 2.7 6.9 140.2 1.5 47.1 27.0 107.8 7.6 2.4 12.1 4.0 1.0 0.0 5.3 8.0 46.8 0.3 287.0 98.0 13.1 2.8 305.9 0.0 2.6 15.1 28.8 0.0 0.4 146.1 9.3 15.8 3.4 94.0 0.2 7.6 270.2 0.8 0.0 0.9 22.9 7.6 31.4 34.0 8514.1 2.3 15.0 0.2 14.2 77.4 DMP1 ENSG00000152592 "Dentin matrix acidic phosphoprotein 1" Q13316 4 87650280-87664361 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037465 Approved "Secreted to extracellular matrix" NA NA 64000 "Cluster 29: U-266 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA037465: AB_10672492" "unprognostic (6.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-3)" "unprognostic (1.80e-1)" "unprognostic (4.96e-3)" "unprognostic (7.73e-2)" "unprognostic (3.88e-1)" "unprognostic (1.11e-1)" "unprognostic (1.35e-2)" "unprognostic (8.50e-9)" "unprognostic (5.82e-2)" "unprognostic (1.49e-2)" "unprognostic (2.77e-1)" "unprognostic (1.74e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DMRT1 "CT154, DMT1" ENSG00000137090 "Doublesex and mab-3 related transcription factor 1" Q9Y5R6 9 841690-969090 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 94 "testis: 26.9" "Group enriched" "Detected in some" 5 "Early spermatids: 44.0;Spermatogonia: 153.2" "Cancer enriched" "Detected in some" 9 "testis cancer: 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA027850 Enhanced NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA027850: AB_10600868" "unprognostic (3.23e-1)" "unprognostic (1.91e-1)" "unprognostic (9.75e-4)" "unprognostic (1.34e-1)" "unprognostic (2.50e-1)" "unprognostic (3.08e-1)" "unprognostic (1.45e-1)" "unprognostic (1.78e-2)" "unprognostic (1.03e-1)" "unprognostic (5.60e-2)" "unprognostic (3.06e-2)" "unprognostic (1.02e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.0 0.0 0.0 17.0 3.4 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 4.9 153.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DMRTA2 ENSG00000142700 "DMRT like family A2" Q96SC8 1 50417550-50423443 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 2.6;esophagus: 1.5;pituitary gland: 2.0;testis: 1.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.9;Basal squamous epithelial cells: 17.6;Early spermatids: 10.8;Squamous epithelial cells: 5.9" "Cancer enhanced" "Detected in many" "glioma: 5.3" "Region enhanced" "Detected in single" "white matter: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.1;HBEC3-KT: 3.3;RH-30: 11.7;SH-SY5Y: 2.4;SiHa: 2.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA043098, HPA062958" Uncertain Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 61: Squamous epithelial cells - Keratinization" Mitochondria Nucleoplasm "HPA043098: AB_10796684, HPA062958: AB_2684911" "unprognostic (1.60e-1)" "unprognostic (4.56e-3)" "unprognostic (2.62e-1)" "unprognostic (3.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.75e-2)" "unprognostic (1.15e-2)" "unprognostic (3.29e-1)" "unprognostic (6.89e-2)" "unprognostic (4.79e-1)" "unprognostic (7.47e-2)" "unprognostic (1.21e-3)" "unprognostic (7.08e-3)" "unprognostic (4.16e-2)" "unprognostic (7.85e-2)" "unprognostic (2.68e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.4 0.4 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 1.4 0.0 0.9 3.3 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 2.4 2.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.4 0.3 0.2 0.6 0.5 0.3 0.2 0.8 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 17.6 0.0 0.1 0.0 1.3 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 10.8 0.1 0.1 0.1 1.2 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.2 1.3 1.0 5.9 0.0 0.0 0.0 0.0 0.1 0.0 DNAAF3 "C19orf51, CILD2, FLJ36139, FLJ40069, PCD, PF22" ENSG00000167646 "Dynein axonemal assembly factor 3" Q8N9W5 19 55158661-55166722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "fallopian tube: 40.8;testis: 65.4" "Group enriched" "Detected in many" 5 "Early spermatids: 395.2;Late spermatids: 722.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 26.2;HEL: 31.6;K-562: 25.3;U-937: 18.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056220 Approved "Nuclear bodies,Mitochondria" No No "Cluster 49: Ciliated cells - Cilium organization" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "Nuclear bodies" "HPA056220: AB_2683071" "unprognostic (1.71e-2)" "unprognostic (2.67e-2)" "unprognostic (6.10e-2)" "unprognostic (9.93e-3)" "unprognostic (1.77e-1)" "unprognostic (1.87e-1)" "unprognostic (2.22e-2)" "unprognostic (1.82e-1)" "unprognostic (5.36e-2)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (1.83e-5)" "unprognostic (1.35e-2)" "unprognostic (1.31e-1)" "unprognostic (2.35e-2)" "unprognostic (8.03e-2)" 0.4 1.8 1.5 0.0 1.2 0.0 0.6 0.9 0.7 2.5 6.1 0.3 0.1 0.9 3.4 0.6 40.8 0.6 5.0 1.5 2.3 2.7 0.6 4.3 0.1 4.0 8.2 0.2 1.6 3.5 0.7 0.1 4.7 0.3 0.1 0.4 0.4 0.9 0.1 0.9 0.3 0.2 3.1 0.3 0.3 65.4 1.5 0.5 2.3 0.0 0.1 0.1 0.4 2.1 8.8 6.6 0.6 6.7 0.1 0.0 0.6 0.1 0.2 1.0 0.7 0.3 4.0 10.5 2.5 0.3 1.9 10.1 1.5 3.0 0.4 0.0 26.2 31.6 0.5 0.5 0.2 13.6 3.1 0.2 4.0 1.7 2.2 0.9 0.5 4.7 25.3 13.9 0.4 5.9 0.4 0.3 0.5 9.5 15.0 16.5 1.0 3.2 5.4 0.2 0.8 2.6 1.1 1.1 1.6 0.2 8.3 0.4 1.0 0.8 3.9 4.0 0.2 0.4 2.5 0.6 4.9 18.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.2 0.9 0.7 1.5 2.3 4.0 8.2 4.7 3.1 1.5 2.1 0.2 0.0 0.5 0.0 0.0 3.2 0.0 4.7 4.6 0.0 1.1 0.6 3.0 1.5 7.5 7.3 0.0 0.0 0.0 0.3 7.9 2.7 395.2 55.8 0.5 0.6 0.0 0.0 0.5 1.0 0.1 1.2 0.0 1.3 0.0 1.9 0.7 0.4 0.2 0.0 0.5 0.5 12.2 0.0 0.4 722.0 4.4 4.2 0.0 0.0 0.0 2.1 0.0 0.5 0.1 0.2 0.1 3.0 0.0 0.1 0.0 5.1 75.2 0.0 0.0 0.0 2.3 104.8 18.6 0.3 1.3 0.0 0.1 1.1 0.4 0.2 DNAAF6 "CXorf41, MGC35261, NYSAR97, PIH1D3, TWISTER" ENSG00000080572 "Dynein axonemal assembly factor 6" Q9NQM4 X 107206611-107244247 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "fallopian tube: 12.1;testis: 12.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 3.0" HPA072496 Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "HPA072496: AB_2732202" "unprognostic (8.66e-2)" "unprognostic (2.75e-3)" "unprognostic (7.73e-4)" "unprognostic (3.37e-1)" "unprognostic (8.61e-2)" "unprognostic (4.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.77e-2)" 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.3 0.2 0.3 1.0 0.0 0.0 0.1 0.6 0.0 12.1 0.0 0.0 0.3 0.4 0.1 0.0 1.5 0.0 1.6 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 12.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.2 0.3 0.4 1.6 1.2 0.9 0.7 0.3 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DNAH10 FLJ43808 ENSG00000197653 "Dynein axonemal heavy chain 10" Q8IVF4 12 123762188-123935720 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;choroid plexus: 2.6;fallopian tube: 4.1;testis: 3.0" "Group enriched" "Detected in many" 5 "Early spermatids: 35.5;Endometrial ciliated cells: 88.5;Late spermatids: 68.9;Respiratory ciliated cells: 88.0" "Cancer enhanced" "Detected in single" "testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039066 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "HPA039066: AB_10673237" "unprognostic (1.37e-1)" "unprognostic (1.78e-1)" "unprognostic (6.08e-3)" "unprognostic (9.90e-3)" "unprognostic (2.16e-1)" "unprognostic (8.91e-2)" "unprognostic (3.39e-2)" "unprognostic (1.86e-1)" "unprognostic (5.59e-2)" "unprognostic (1.08e-2)" "unprognostic (7.28e-3)" "unprognostic (5.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.33e-1)" "unprognostic (7.23e-2)" "unprognostic (1.22e-2)" "unprognostic (9.11e-3)" 0.2 0.0 1.0 0.0 0.7 1.2 0.0 0.8 0.4 0.6 2.6 0.0 0.1 0.1 0.0 0.0 4.1 0.0 0.1 1.0 1.3 0.1 0.0 1.1 0.0 4.6 4.9 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 3.3 0.1 0.0 3.0 1.1 0.0 0.1 0.0 0.0 0.1 0.1 1.2 0.0 0.0 0.0 0.5 0.9 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.8 0.4 1.0 1.3 4.6 4.9 2.5 3.3 1.1 1.2 0.0 0.0 5.5 2.0 0.7 0.0 0.0 1.6 0.0 1.2 0.1 0.3 2.3 0.0 12.9 0.0 0.0 0.0 0.6 0.0 1.9 0.0 35.5 88.5 1.2 0.3 0.0 0.4 7.2 0.0 0.0 0.8 0.0 2.1 0.0 0.1 0.4 0.0 0.1 0.0 6.1 0.2 0.0 0.0 0.0 68.9 0.0 0.3 0.0 0.0 0.4 1.0 1.0 2.0 5.0 0.1 0.0 0.0 0.0 0.0 1.2 2.9 88.0 1.4 13.1 0.6 1.0 9.9 2.1 0.0 0.0 0.0 0.4 0.9 0.4 0.1 DNAH14 "C1orf67, DKFZp781B1548, Dnahc14, HL-18, HL18, MGC27277" ENSG00000185842 "Dynein axonemal heavy chain 14" Q0VDD8 1 224896262-225399292 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.1" "Cell type enhanced" "Detected in many" "Early spermatids: 135.0;Excitatory neurons: 65.4;Spermatocytes: 74.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 48.8" "Low region specificity" "Detected in many" "HPA027718, HPA028545, HPA031379" Uncertain Supported Centrosome NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Centrosome "HPA027718: AB_10601210, HPA028545: AB_2672665, HPA031379: AB_2673851" "unprognostic (1.16e-1)" "unprognostic (1.77e-2)" "unprognostic (2.95e-1)" "unprognostic (1.86e-2)" "unprognostic (5.92e-2)" "unprognostic (1.09e-3)" "unprognostic (9.94e-4)" "unprognostic (4.23e-2)" "unprognostic (1.56e-2)" "unprognostic (3.67e-2)" "unprognostic (2.12e-1)" "unprognostic (2.51e-1)" "unprognostic (2.33e-9)" "unprognostic (6.76e-2)" "unprognostic (7.39e-2)" "unprognostic (1.27e-1)" "unprognostic (6.78e-2)" 1.1 3.2 4.2 0.7 3.5 1.9 3.2 0.9 3.4 1.8 4.4 1.9 1.0 1.9 3.6 1.1 1.6 1.6 1.3 3.4 9.2 5.4 5.7 2.3 0.4 3.8 4.3 3.7 5.6 2.1 6.6 1.5 3.9 3.2 2.3 2.7 1.5 1.4 0.1 0.4 0.6 1.1 2.9 0.4 2.6 22.1 8.8 1.4 4.4 0.2 0.2 1.8 1.1 2.9 19.7 9.9 8.9 9.8 3.5 7.1 21.3 4.0 3.7 7.2 6.3 15.6 21.1 0.0 9.7 4.1 0.0 0.2 13.8 3.8 12.2 0.0 23.0 9.4 7.2 3.4 4.3 19.6 3.1 6.9 8.3 10.0 6.9 7.7 2.4 13.5 48.8 0.0 12.4 5.2 3.6 20.3 25.1 22.1 12.0 0.0 33.8 18.0 6.7 9.0 14.9 16.9 15.4 11.5 32.1 14.8 21.2 16.9 0.4 0.1 14.4 0.3 0.1 20.9 14.1 0.2 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.8 0.0 0.0 0.2 0.0 4.2 3.5 0.9 3.4 3.4 9.2 3.8 4.3 3.9 2.9 8.8 2.9 2.5 12.8 11.5 2.3 0.6 2.0 14.0 6.0 3.4 28.1 10.1 6.2 6.5 10.0 5.7 20.2 33.3 10.6 1.3 2.1 7.9 11.2 135.0 13.1 13.2 3.4 8.3 6.7 65.4 10.0 12.4 4.5 6.6 12.2 14.0 23.3 1.4 7.7 3.4 28.6 44.0 5.2 4.1 0.0 1.2 45.9 2.8 1.2 3.6 6.5 1.0 8.0 1.0 23.6 8.4 9.4 1.1 3.4 1.2 11.2 0.5 8.4 6.7 3.9 6.6 0.5 2.7 74.5 24.9 2.8 0.9 11.5 1.4 10.1 5.0 7.1 DNAI4 "DIC4, FLJ23129, WDR78" ENSG00000152763 "Dynein axonemal intermediate chain 4" Q5VTH9 1 66812885-66924856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 27.7;testis: 35.2" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 3.8" "Lineage enriched" "Detected in single" 4 "NK-cells: 3.8" "Cell line enhanced" "Detected in many" "ASC TERT1: 7.0;RPTEC TERT1: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (4.26e-2)" "unprognostic (4.04e-1)" "unprognostic (1.58e-3)" "unprognostic (2.19e-2)" "unprognostic (1.85e-1)" "unprognostic (1.71e-2)" "unprognostic (1.74e-1)" "unprognostic (1.01e-1)" "unprognostic (8.19e-2)" "unprognostic (4.00e-1)" "unprognostic (1.68e-3)" "unprognostic (2.08e-2)" "prognostic favorable (9.60e-5)" "unprognostic (1.98e-1)" "unprognostic (5.79e-2)" "unprognostic (5.03e-2)" "unprognostic (1.69e-1)" 1.5 1.7 3.3 0.5 3.0 0.1 3.0 2.0 1.8 4.0 19.4 5.4 0.7 3.0 5.0 0.5 27.7 2.5 1.2 2.6 4.1 6.3 1.2 4.2 1.0 12.6 10.2 3.0 1.4 7.0 2.8 2.1 7.4 1.8 4.1 4.1 1.1 2.0 0.5 1.0 0.6 1.3 9.5 0.9 0.8 35.2 3.8 2.3 5.9 0.3 0.7 0.9 0.9 8.6 2.9 1.2 1.6 2.1 4.8 7.0 0.6 1.3 2.2 1.6 1.7 0.3 2.4 1.5 0.3 1.3 5.0 0.2 1.1 0.3 2.5 0.2 0.4 0.4 0.7 0.2 1.6 0.1 0.0 3.3 3.5 6.0 1.2 5.8 0.6 1.5 0.4 0.1 2.8 1.1 0.7 0.5 2.1 1.0 0.6 0.7 0.0 0.0 11.4 0.0 1.9 0.9 1.4 0.5 1.1 1.7 0.5 1.0 0.2 0.7 0.0 4.7 0.7 0.5 0.0 3.2 1.4 0.3 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.3 0.1 0.0 0.9 0.5 0.2 0.1 3.8 0.0 0.0 0.1 0.1 3.3 3.0 2.0 1.8 2.6 4.1 12.6 10.2 7.4 9.5 3.8 8.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 DNAJB13 "RSPH16A, TSARG6" ENSG00000187726 "DnaJ heat shock protein family (Hsp40) member B13" P59910 11 73951026-73970366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Chaperone "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 53.2;testis: 18.9" "Group enriched" "Detected in some" 4 "Early spermatids: 90.6;Endometrial ciliated cells: 114.8;Late spermatids: 62.9;Respiratory ciliated cells: 104.2" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.7;Karpas-707: 2.6;RPTEC TERT1: 4.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA052465, HPA061330" Enhanced Approved "Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA052465: AB_2681842, HPA061330: AB_2732659" "unprognostic (1.07e-1)" "unprognostic (3.23e-2)" "unprognostic (3.27e-3)" "unprognostic (1.56e-2)" "unprognostic (1.03e-1)" "unprognostic (1.20e-4)" "unprognostic (1.30e-2)" "unprognostic (1.72e-4)" "unprognostic (5.00e-2)" "unprognostic (4.73e-2)" "unprognostic (6.30e-2)" "unprognostic (1.22e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (3.32e-2)" "unprognostic (1.41e-1)" "unprognostic (9.44e-2)" "unprognostic (2.40e-2)" 0.1 0.1 1.5 1.2 1.5 4.4 0.2 1.0 1.4 5.5 12.2 0.1 0.6 2.0 5.2 0.1 53.2 2.2 0.1 2.0 1.9 1.0 0.1 3.1 2.1 4.8 5.7 0.3 0.8 0.1 1.1 0.5 3.6 0.9 0.0 0.4 0.6 2.9 0.3 0.1 2.9 0.1 4.0 1.3 0.2 18.9 2.4 0.0 0.2 0.0 0.0 0.2 0.1 1.8 0.0 0.4 0.3 0.7 0.0 0.1 0.2 0.1 0.0 0.2 0.0 0.7 0.2 0.9 2.1 0.2 0.3 0.5 0.1 0.0 0.0 2.7 0.3 1.0 0.9 0.3 0.0 0.2 0.6 0.0 0.4 0.1 0.0 0.0 0.0 1.4 0.2 2.6 0.4 0.3 0.6 0.9 0.2 0.2 1.5 0.4 1.2 1.1 4.5 0.5 0.3 1.0 0.5 2.2 0.2 0.4 0.3 0.7 0.0 0.0 0.6 0.6 0.0 2.2 2.0 1.9 0.0 0.3 0.1 0.7 0.1 0.2 0.2 0.0 0.0 0.3 0.2 0.1 0.1 0.2 0.1 0.3 0.0 0.1 0.0 0.7 0.2 0.1 1.5 1.5 1.0 1.4 2.0 1.9 4.8 5.7 3.6 4.0 2.4 1.8 0.2 3.2 0.0 2.0 0.0 0.0 1.9 11.1 0.0 0.2 0.1 0.3 0.2 0.0 7.6 1.8 0.0 0.1 0.0 0.1 0.0 1.7 90.6 114.8 2.4 0.2 0.0 0.0 0.4 0.0 0.1 0.5 0.0 13.4 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.3 10.2 0.0 0.0 62.9 1.2 0.3 1.8 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 1.2 0.0 1.3 1.4 1.0 104.2 0.9 0.0 1.1 3.3 19.5 1.5 0.0 0.0 0.0 0.3 0.0 0.0 1.2 DNAJC18 MGC29463 ENSG00000170464 "DnaJ heat shock protein family (Hsp40) member C18" Q9H819 5 139408588-139444491 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 77.9" "Group enriched" "Detected in many" 21 "Early spermatids: 529.9;Late spermatids: 1332.4" "Cancer enhanced" "Detected in many" "glioma: 8.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036538, HPA060154" Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" "Cell Junctions" Cytosol "HPA036538: AB_10670802, HPA060154: AB_2684212" "unprognostic (2.03e-1)" "unprognostic (1.16e-1)" "unprognostic (1.13e-1)" "unprognostic (1.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (2.73e-3)" "unprognostic (8.76e-2)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "prognostic favorable (5.89e-4)" "unprognostic (8.09e-2)" "unprognostic (1.69e-2)" "unprognostic (3.55e-2)" "unprognostic (1.81e-1)" "unprognostic (6.96e-2)" "unprognostic (1.97e-2)" 6.1 3.1 7.7 1.5 7.4 0.9 5.2 7.9 9.5 6.9 4.5 5.8 0.7 6.5 2.3 2.4 6.6 2.1 6.6 7.2 8.3 5.1 1.0 6.8 1.7 8.3 7.2 7.5 1.9 3.6 8.0 2.1 8.6 4.5 1.3 7.6 3.0 2.9 7.5 2.4 3.4 3.5 6.6 2.8 3.5 77.9 7.6 1.6 4.3 4.3 1.2 5.4 4.7 8.1 1.2 1.2 7.9 7.4 4.3 4.5 0.9 2.4 5.3 4.2 7.6 2.9 0.9 5.4 6.4 3.8 9.2 2.1 4.5 7.3 4.4 12.5 5.9 3.7 2.6 1.3 3.4 0.4 1.7 6.1 0.9 7.0 4.3 7.1 5.8 2.0 1.7 5.1 6.3 0.6 1.6 1.7 5.4 0.4 1.8 4.5 8.5 0.9 2.5 1.3 7.3 7.6 2.5 0.9 5.8 10.1 1.1 2.7 7.5 5.5 0.0 1.7 5.2 6.0 8.6 2.8 2.9 2.7 2.4 0.5 0.4 0.5 0.5 0.3 0.7 0.8 0.7 0.9 0.3 0.9 0.7 0.4 0.1 1.4 0.2 0.5 1.7 0.3 7.7 7.4 7.9 9.5 7.2 8.3 8.3 7.2 8.6 6.6 7.6 8.1 14.9 3.2 3.9 12.7 5.0 1.5 8.3 9.4 7.4 29.4 2.2 5.5 11.0 2.8 5.8 1.8 10.4 4.7 7.0 0.7 1.9 4.9 529.9 2.1 11.0 15.2 12.6 1.7 33.1 1.1 3.4 11.3 2.0 2.3 9.5 14.4 13.6 0.2 2.9 16.8 39.0 2.1 0.0 3.5 2.4 1332.4 14.0 3.4 5.4 8.4 3.7 13.7 3.1 17.6 22.1 2.0 1.7 18.8 7.6 3.9 0.8 3.6 3.3 20.1 19.7 21.1 14.2 43.8 12.9 2.6 1.1 4.7 4.2 9.8 1.3 3.4 DNAJC25-GNG10 ENSG00000244115 "DNAJC25-GNG10 readthrough" 9 111631386-111670229 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 10.8;Club cells: 7.4;granulocytes: 6.3;Respiratory ciliated cells: 8.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "neutrophil: 73.1" "Lineage enriched" "Detected in all" 10 "granulocytes: 73.1" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" 13.6 11.4 8.3 9.6 9.0 11.7 9.8 8.2 11.1 9.5 10.3 9.9 4.9 8.6 5.7 5.3 9.2 4.6 9.8 9.4 9.1 9.5 8.7 10.8 6.5 9.8 9.0 6.8 5.1 12.2 11.7 10.3 9.1 9.1 4.7 2.5 7.0 5.8 6.8 3.3 6.1 7.4 8.9 10.9 7.6 3.4 9.6 4.8 7.1 8.1 4.3 14.1 7.4 10.0 13.4 7.5 6.7 12.3 22.6 22.3 10.7 17.0 16.6 12.1 10.0 10.6 11.8 1.1 7.2 17.5 23.9 12.5 11.7 17.6 20.7 3.2 8.8 2.5 9.1 8.3 15.1 6.5 6.4 15.6 15.3 9.8 27.9 16.9 16.4 7.2 6.0 5.7 20.1 8.1 4.7 4.7 9.1 24.5 14.8 4.2 32.6 1.1 22.6 8.8 8.8 7.2 14.2 5.4 16.1 11.4 14.0 7.6 13.8 12.9 10.3 27.0 15.5 5.6 5.0 2.3 19.0 14.6 8.5 3.9 6.9 9.4 1.5 6.3 2.8 1.3 2.1 1.9 5.3 1.6 2.3 1.4 73.1 1.8 5.6 3.6 4.3 4.2 8.3 9.0 8.2 11.1 9.4 9.1 9.8 9.0 9.1 8.9 9.6 10.0 0.9 12.8 10.8 0.0 0.7 0.0 0.4 0.0 0.6 0.0 0.4 0.3 0.0 0.0 7.4 0.0 0.0 0.2 0.3 0.0 0.0 0.4 0.1 0.3 1.2 1.5 2.4 0.4 0.6 0.2 0.3 1.2 0.5 0.3 6.3 0.2 0.0 0.2 0.5 0.0 0.6 0.1 0.0 0.3 0.0 0.1 0.0 3.5 0.0 0.0 1.1 0.8 0.0 0.0 0.2 0.5 1.2 0.0 0.3 0.2 0.3 0.2 8.0 0.1 0.0 0.6 0.8 0.0 0.0 1.3 0.0 0.1 0.8 0.5 0.2 0.4 DNAJC3 "ERdj6, HP58, P58, p58(IPK), P58IPK, PRKRI" ENSG00000102580 "DnaJ heat shock protein family (Hsp40) member C3" Q13217 13 95677139-95794988 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Antiviral defense, Stress response, Translation regulation, Unfolded protein response" "Chaperone, Repressor" "Deafness, Diabetes mellitus, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039336, HPA041326" Uncertain Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 4900000 "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA039336: AB_2676451, HPA041326: AB_2677412" "unprognostic (1.44e-2)" "unprognostic (8.08e-2)" "unprognostic (2.12e-2)" "prognostic favorable (3.47e-5)" "unprognostic (8.18e-2)" "unprognostic (5.78e-2)" "unprognostic (1.09e-1)" "unprognostic (2.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.45e-1)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (9.69e-2)" "unprognostic (7.19e-2)" "unprognostic (3.37e-2)" "unprognostic (8.30e-3)" "unprognostic (8.18e-2)" 21.0 20.0 10.7 22.5 13.0 45.6 21.3 13.0 11.4 35.1 22.3 25.2 23.8 20.4 38.9 15.9 20.4 22.0 16.6 10.0 14.1 25.5 41.8 22.9 15.0 15.1 12.5 15.8 36.0 24.4 16.2 24.7 15.5 34.5 26.4 9.9 36.3 26.0 9.3 10.9 24.0 22.3 13.4 19.8 28.8 12.7 14.6 11.3 52.8 11.2 17.8 22.1 11.9 16.4 32.4 18.0 14.2 40.7 57.7 28.6 42.6 44.6 40.3 20.2 18.4 22.7 66.5 29.5 41.5 45.0 28.5 32.3 18.7 34.1 30.7 28.8 8.4 40.7 24.6 36.5 79.1 49.8 51.6 34.3 35.7 29.7 68.2 36.9 44.4 13.2 13.9 0.3 34.4 13.1 17.0 17.8 10.6 75.2 13.9 17.1 24.8 22.9 44.9 39.5 8.2 15.6 31.6 74.9 22.5 32.4 37.3 54.6 50.8 39.0 13.3 26.2 23.3 60.6 28.4 13.4 65.6 29.6 54.9 64.7 25.5 86.2 23.9 32.1 25.3 11.2 19.6 20.1 17.2 9.0 13.7 18.7 77.1 22.8 36.0 45.9 13.4 15.7 10.7 13.0 13.0 11.4 10.0 14.1 15.1 12.5 15.5 13.4 14.6 16.4 81.7 80.1 71.3 47.3 61.1 94.1 88.5 81.1 33.6 25.7 65.2 35.9 58.2 81.5 83.4 47.8 27.1 57.1 109.6 69.0 21.5 98.8 160.5 58.0 87.5 64.8 41.9 33.7 30.1 118.7 135.5 99.6 56.6 94.5 67.8 34.4 68.6 140.7 78.8 25.2 37.3 84.9 69.2 70.5 130.2 33.6 71.7 82.0 119.2 47.8 63.1 38.7 51.5 53.3 58.9 97.6 52.4 75.6 214.3 151.2 58.1 71.1 96.7 19.6 92.1 80.8 104.5 47.1 79.9 38.1 92.9 189.8 67.0 53.3 63.8 124.4 DNASE1 DNL1 ENSG00000213918 "Deoxyribonuclease 1" P24855 16 3611728-3680143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Actin-binding, Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 34.5;kidney: 34.2" "Cell type enriched" "Detected in many" 11 "Proximal enterocytes: 715.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010703 Enhanced Supported Vesicles "Secreted in other tissues" NA NA 420000 "Cluster 49: Eosinophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA010703: AB_10600806" "unprognostic (5.18e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.38e-1)" "unprognostic (1.90e-2)" "unprognostic (3.73e-2)" "unprognostic (3.82e-1)" "unprognostic (3.20e-1)" "unprognostic (9.91e-2)" "unprognostic (1.69e-3)" "unprognostic (5.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.14e-4)" 4.6 5.0 5.1 6.6 5.6 4.3 4.6 13.4 6.4 9.8 6.9 6.1 29.7 5.2 5.0 7.1 6.8 2.7 5.5 5.8 4.9 34.2 5.9 4.9 10.0 6.0 5.2 7.5 23.6 2.7 16.3 4.2 6.6 11.6 5.0 4.4 4.9 2.5 3.7 7.8 34.5 2.7 3.2 9.2 11.2 9.2 5.8 9.4 7.4 1.3 8.7 6.0 8.5 9.7 2.9 6.5 11.4 5.9 3.3 2.8 5.2 4.7 0.8 3.7 5.3 8.0 6.9 12.3 3.6 0.7 7.8 4.8 4.2 1.3 3.9 5.5 6.4 4.4 11.3 5.4 1.7 2.9 9.6 2.3 4.8 5.0 1.2 5.8 2.5 10.3 11.2 5.0 3.2 12.3 6.3 13.6 6.9 8.7 3.6 14.9 5.3 5.7 3.1 2.5 8.1 7.6 3.5 10.5 1.9 5.7 10.4 7.7 3.4 6.8 5.0 4.3 2.5 4.8 7.5 21.4 1.7 5.7 6.6 2.7 1.1 3.2 1.5 0.7 1.0 1.4 1.2 1.3 0.6 2.1 1.3 1.8 5.0 1.0 0.7 1.1 1.4 0.5 5.1 5.6 13.4 6.4 5.8 4.9 6.0 5.2 6.6 3.2 5.8 9.7 4.9 9.6 10.3 27.1 9.1 2.7 8.6 3.1 10.8 27.3 5.5 4.8 6.0 4.3 9.7 16.5 22.9 8.6 9.3 11.8 56.7 5.3 19.3 9.8 10.0 7.7 14.3 7.6 20.5 11.0 4.1 7.4 13.3 8.4 2.5 23.3 7.5 1.8 3.9 25.2 22.0 38.6 20.3 5.0 4.2 52.4 8.4 4.4 1.8 15.9 13.2 8.6 30.9 22.1 20.6 5.3 61.4 7.9 7.2 12.4 715.5 2.4 9.1 17.9 0.0 13.6 6.3 28.5 24.5 5.8 3.8 6.2 12.2 10.4 33.4 6.3 DNASE1L1 "DNAS1L1, DNASEX, DNL1L, XIB" ENSG00000013563 "Deoxyribonuclease 1 like 1" P49184 X 154401236-154412112 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 147.0" "Cell type enhanced" "Detected in many" "Kupffer cells: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072635 Approved "Intracellular and membrane" NA NA 96000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "HPA072635: AB_2686542" "unprognostic (5.27e-2)" "unprognostic (1.95e-1)" "unprognostic (4.57e-3)" "unprognostic (2.97e-1)" "unprognostic (1.27e-2)" "unprognostic (1.59e-3)" "unprognostic (3.82e-2)" "unprognostic (3.08e-2)" "unprognostic (2.88e-1)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (4.98e-1)" "prognostic favorable (2.19e-4)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "unprognostic (6.75e-2)" 18.7 26.6 12.6 13.0 12.1 24.1 17.8 11.7 14.1 15.8 26.6 15.2 15.2 15.8 22.5 21.6 14.0 13.0 43.2 13.5 14.3 20.9 18.8 22.0 16.4 12.2 13.4 13.7 12.8 22.7 20.1 16.1 12.6 15.1 12.3 3.9 22.0 11.3 147.0 11.3 19.3 11.3 13.0 28.5 18.1 7.7 13.6 8.9 24.1 94.8 13.2 13.5 16.9 11.9 19.7 19.6 6.3 12.2 56.6 74.5 7.7 54.5 85.3 17.6 34.6 5.7 28.0 32.9 68.2 103.0 67.4 9.6 7.6 31.0 12.8 9.9 13.0 4.8 20.6 7.1 38.8 8.6 33.4 55.6 35.7 39.6 40.0 47.9 76.4 5.3 6.5 34.0 61.1 33.0 3.6 4.2 5.0 35.5 22.1 7.3 28.5 52.9 31.0 9.7 20.2 12.0 17.1 29.9 22.5 13.9 11.9 7.8 112.9 17.7 20.3 25.6 10.9 64.2 15.4 34.4 26.6 14.4 22.4 13.0 12.0 17.1 3.5 21.6 4.0 6.2 3.3 3.1 14.5 4.1 2.4 2.2 7.0 4.6 20.9 8.3 4.9 6.4 12.6 12.1 11.7 14.1 13.5 14.3 12.2 13.4 12.6 13.0 13.6 11.9 20.1 6.4 6.5 3.3 8.0 1.3 7.1 11.1 9.6 1.8 5.1 3.8 2.0 5.7 5.4 5.5 0.0 5.3 6.7 15.5 9.8 6.1 0.1 5.8 5.7 17.7 6.1 6.5 3.2 10.2 23.3 5.2 11.7 7.5 13.3 4.9 23.2 8.6 29.1 0.0 2.2 10.4 6.1 36.6 11.7 1.2 3.4 25.4 16.0 4.7 22.9 12.8 7.2 0.0 0.5 13.5 18.1 2.6 6.8 5.9 27.0 9.6 7.0 1.4 0.0 16.7 3.3 0.4 0.4 10.4 1.7 8.9 6.0 3.2 10.9 10.9 DNASE1L2 DNAS1L2 ENSG00000167968 "Deoxyribonuclease 1 like 2" Q92874 16 2235816-2238711 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 45.8" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Excitatory neurons: 2.5;Inhibitory neurons: 2.6;Ionocytes: 4.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044714 Uncertain Mitochondria "Secreted in other tissues" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA044714: AB_10962870" "unprognostic (9.88e-2)" "unprognostic (1.11e-3)" "unprognostic (6.80e-4)" "unprognostic (4.29e-2)" "unprognostic (2.35e-1)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (2.50e-1)" "unprognostic (2.72e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-3)" "unprognostic (2.17e-2)" "unprognostic (4.67e-4)" "unprognostic (1.40e-4)" "unprognostic (3.51e-1)" "unprognostic (2.28e-1)" "unprognostic (2.94e-4)" 0.9 1.1 4.8 0.4 5.2 0.5 1.2 7.3 8.4 1.8 2.0 1.0 0.5 1.1 0.2 0.9 1.2 0.3 0.9 4.2 4.5 4.6 1.7 0.9 0.4 6.1 4.5 2.0 1.9 0.1 4.7 0.7 6.4 2.3 0.1 1.1 0.8 0.1 0.7 45.8 1.0 0.1 3.7 2.6 1.0 1.5 4.9 0.6 6.0 0.1 0.8 0.9 1.6 7.6 1.4 2.9 1.2 1.3 1.0 0.5 5.0 0.5 0.3 1.1 0.6 3.2 3.0 1.9 1.5 0.1 0.4 0.5 0.4 0.2 0.1 3.8 2.8 0.8 5.6 0.7 0.1 0.9 3.0 0.6 1.0 0.8 0.2 1.1 0.2 2.1 2.7 2.8 0.4 3.4 2.7 5.6 1.2 0.4 1.9 5.0 1.4 2.7 0.6 0.6 2.5 1.3 0.7 1.1 2.1 0.3 4.5 2.0 0.1 2.4 3.1 1.4 1.0 6.8 3.5 1.8 0.8 1.8 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.8 5.2 7.3 8.4 4.2 4.5 6.1 4.5 6.4 3.7 4.9 7.6 0.2 0.0 0.6 2.9 0.1 0.1 0.1 0.4 0.0 0.7 0.7 0.5 0.7 1.5 0.1 0.0 0.0 0.1 0.2 0.5 0.0 0.1 0.1 0.2 1.0 0.3 0.0 0.0 2.5 0.0 0.1 0.1 1.1 0.4 0.0 0.6 0.4 0.4 0.1 1.7 2.6 0.1 4.1 0.0 0.0 0.1 0.6 0.1 0.0 1.0 0.1 0.9 0.0 1.0 1.8 0.0 0.1 0.0 0.5 0.2 0.8 0.1 0.1 1.8 0.0 0.0 0.2 0.1 0.5 0.0 0.1 0.0 0.2 0.3 0.3 0.1 DNASE1L3 "DNAS1L3, LSD" ENSG00000163687 "Deoxyribonuclease 1 like 3" Q13609 3 58192257-58214697 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Necrosis" "Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "liver: 271.4;lymphoid tissue: 263.5" "Cell type enriched" "Detected in many" 6 "Hepatic stellate cells: 1670.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 424.7" "Lineage enriched" "Detected in many" 20 "dendritic cells: 424.7" "Cell line enhanced" "Detected in some" "BEWO: 1.9;Karpas-707: 1.1;RPMI-8226: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA019955 Approved "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA019955: AB_1847805" "unprognostic (7.49e-3)" "unprognostic (3.08e-3)" "unprognostic (9.75e-3)" "unprognostic (3.92e-3)" "unprognostic (2.93e-3)" "unprognostic (1.01e-2)" "prognostic favorable (1.20e-6)" "unprognostic (4.74e-4)" "unprognostic (2.10e-1)" "unprognostic (9.71e-2)" "unprognostic (1.91e-3)" "unprognostic (6.95e-2)" "prognostic favorable (1.06e-7)" "unprognostic (7.57e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (5.64e-3)" 20.6 41.0 0.6 38.0 0.5 2.9 10.3 1.5 0.7 4.4 5.4 31.4 29.7 1.7 1.5 16.9 2.8 7.9 14.7 0.6 0.5 47.7 271.4 18.0 38.7 0.6 0.5 1.1 1.1 1.7 20.3 7.1 0.8 1.8 42.2 0.5 8.7 1.4 1.0 4.5 42.5 3.5 0.5 263.5 5.9 3.8 0.8 22.6 16.5 0.3 54.0 12.0 9.4 1.2 0.0 0.2 0.1 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.7 0.0 0.3 0.1 0.0 0.3 0.0 0.1 0.0 0.7 0.0 0.2 1.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 2.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.3 0.2 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.2 20.4 0.1 0.1 40.4 20.7 0.1 0.0 0.6 0.5 0.2 424.7 0.0 3.4 0.6 0.5 1.5 0.7 0.6 0.5 0.6 0.5 0.8 0.5 0.8 1.2 126.6 0.0 9.8 0.3 25.7 9.2 0.3 1.1 12.0 0.1 0.9 1.4 1.2 35.8 2.0 0.0 0.0 0.1 76.3 0.5 3.9 0.0 1.9 0.4 0.2 239.9 0.0 85.5 0.1 0.4 1.2 6.1 0.0 0.8 1.3 0.1 1670.9 27.1 0.5 1.7 0.1 0.2 0.0 127.1 144.3 3.2 4.1 18.6 3.6 0.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.2 0.3 0.1 3.3 0.0 0.2 0.0 0.3 1.3 0.3 0.2 59.3 16.3 0.3 3.8 2.6 0.0 1.0 DNASE2 "DNL, DNL2" ENSG00000105612 "Deoxyribonuclease 2, lysosomal" O00115 19 12875209-12881466 "Enzymes, Predicted intracellular proteins" Apoptosis "Developmental protein, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 226.7;Paneth cells: 125.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066185 Enhanced "Intracellular and membrane" NA NA 560000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA066185: AB_2685632" "unprognostic (9.62e-2)" "unprognostic (2.19e-3)" "unprognostic (8.97e-2)" "unprognostic (7.45e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (5.42e-2)" "unprognostic (4.85e-2)" "unprognostic (1.40e-1)" "unprognostic (5.12e-2)" "unprognostic (4.37e-2)" "unprognostic (2.58e-2)" "unprognostic (4.69e-2)" "unprognostic (3.57e-1)" "unprognostic (1.98e-1)" 27.0 26.7 17.1 24.0 17.5 9.6 23.3 17.2 19.1 22.7 19.7 24.7 23.7 25.1 29.5 18.9 25.3 25.3 22.7 16.5 17.6 19.2 36.0 37.7 42.2 18.7 18.2 26.1 41.7 43.1 23.8 20.6 19.4 27.7 19.2 5.6 33.0 26.1 19.7 29.2 22.7 22.0 19.3 26.2 30.0 5.9 17.8 20.8 38.7 13.1 26.5 24.3 19.9 23.0 63.7 36.3 2.9 80.8 86.8 46.2 55.0 34.4 87.2 33.2 79.6 3.8 43.6 27.9 97.3 54.9 73.0 71.8 30.7 33.2 16.2 89.8 41.0 13.1 36.8 17.5 68.3 26.5 119.8 46.5 74.5 24.8 36.7 80.2 50.2 42.4 14.0 112.1 20.3 82.7 27.3 14.1 6.1 66.3 60.8 17.1 14.2 64.3 32.9 29.7 17.3 28.6 46.1 65.8 123.5 11.8 98.5 23.4 32.5 67.8 21.4 70.3 31.1 139.9 153.6 35.7 112.9 24.6 34.4 73.5 71.0 10.9 64.5 95.8 53.5 31.1 56.1 68.8 14.0 35.6 49.0 53.7 40.6 70.9 114.2 28.3 85.8 66.4 17.1 17.5 17.2 19.1 16.5 17.6 18.7 18.2 19.4 19.3 17.8 23.0 18.7 25.6 22.4 7.5 25.5 14.5 23.6 56.9 14.2 6.7 22.7 18.5 10.6 28.6 31.0 36.8 4.2 60.0 23.5 17.3 3.9 67.1 0.5 24.1 15.1 21.4 16.4 5.7 1.3 58.3 96.2 27.9 13.7 25.4 22.2 23.8 28.9 26.4 226.7 5.0 1.7 15.0 83.4 87.5 6.8 2.5 32.0 55.5 46.2 2.8 28.4 32.2 33.0 3.0 1.7 39.5 125.0 33.4 36.6 15.1 10.8 6.8 29.9 3.3 13.1 16.5 16.9 0.6 4.8 12.4 12.4 48.0 23.9 23.0 26.2 18.5 DNASE2B DLAD ENSG00000137976 "Deoxyribonuclease 2 beta" Q8WZ79 1 84398484-84415018 "Enzymes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 25 "salivary gland: 170.3" "Cell type enhanced" "Detected in some" "Early spermatids: 1.9;Hofbauer cells: 5.8;Kupffer cells: 1.6;Late spermatids: 3.1;Macrophages: 4.2;Paneth cells: 1.7;Prostatic glandular cells: 2.0" "Group enriched" "Detected in some" 5 "melanoma: 2.8;prostate cancer: 9.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.24e-1)" "unprognostic (3.57e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (4.70e-2)" "unprognostic (3.70e-1)" "unprognostic (2.86e-1)" "unprognostic (1.62e-2)" "unprognostic (9.87e-2)" "unprognostic (7.90e-2)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (3.82e-5)" "unprognostic (5.38e-2)" "unprognostic (1.97e-1)" "unprognostic (6.79e-2)" "unprognostic (3.08e-3)" 0.6 0.1 0.3 0.0 0.6 0.0 0.4 0.3 0.8 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.0 0.3 2.4 0.7 0.5 0.3 0.1 0.8 0.0 0.3 0.0 0.6 6.8 0.5 0.0 170.3 0.0 1.6 0.0 0.1 0.0 0.4 0.4 0.8 0.4 0.4 0.2 0.1 0.2 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.3 0.8 0.4 1.0 0.5 0.3 0.6 0.4 0.4 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.9 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 5.8 0.0 0.4 0.1 0.0 1.6 0.0 3.1 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 1.7 0.0 0.1 2.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 DNM2 "CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII" ENSG00000079805 "Dynamin 2" P50570 19 10718079-10833488 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Phagocytosis" "Hydrolase, Motor protein" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 242.8;Paneth cells: 177.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054246 Supported Approved "Golgi apparatus,Cytosol" NA NA 230000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Cytosol" "HPA054246: AB_2682427" "unprognostic (2.30e-1)" "unprognostic (5.23e-2)" "unprognostic (4.72e-2)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "prognostic favorable (8.91e-4)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.03e-1)" "unprognostic (3.79e-1)" "unprognostic (1.89e-1)" "unprognostic (4.75e-2)" "unprognostic (5.35e-2)" "unprognostic (5.47e-2)" "unprognostic (5.40e-3)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" 55.1 69.9 50.5 63.2 77.8 125.7 46.1 74.1 64.1 49.0 38.8 105.8 65.9 42.2 25.3 67.6 42.5 40.5 87.2 52.3 57.4 72.8 57.2 87.0 62.4 82.7 78.9 36.6 68.2 38.9 41.9 51.3 79.8 47.4 83.9 30.7 55.0 55.7 108.1 92.8 99.6 35.1 60.3 81.0 98.6 55.1 72.9 58.6 47.6 82.8 65.4 64.6 54.5 101.6 116.4 92.8 67.6 54.6 67.6 65.4 86.5 75.1 70.5 108.8 91.7 94.2 74.7 83.2 132.2 81.5 52.5 99.4 92.6 82.1 90.8 103.1 72.4 160.1 81.7 107.1 82.9 87.8 146.5 67.8 62.4 83.5 77.9 66.2 107.3 84.9 131.5 139.1 68.0 140.1 126.3 85.7 76.6 138.3 109.7 125.6 72.6 95.7 71.3 171.1 97.1 63.8 86.6 73.6 54.2 74.9 58.8 106.2 99.6 120.7 40.5 172.0 102.7 112.7 127.3 77.9 89.9 134.0 61.0 3.5 3.5 7.0 4.0 6.2 3.8 2.5 3.0 4.4 4.2 2.1 1.7 3.0 6.5 8.9 8.4 8.4 3.8 4.1 50.5 77.8 74.1 64.1 52.3 57.4 82.7 78.9 79.8 60.3 72.9 101.6 37.8 32.1 22.3 24.8 48.8 23.2 17.1 13.8 22.2 28.8 19.7 16.3 30.3 14.3 25.7 51.5 22.9 25.7 57.2 242.8 50.9 35.2 48.4 32.2 17.9 33.1 21.6 38.1 29.2 32.0 106.9 19.5 168.7 39.7 19.0 36.8 20.3 22.8 49.1 43.7 31.1 106.9 14.2 28.0 39.6 98.0 16.8 55.2 19.6 60.9 43.4 17.2 39.1 23.1 90.9 45.2 177.3 27.8 92.2 20.2 90.7 38.8 18.0 26.3 26.3 18.7 27.6 15.0 12.3 26.6 31.5 31.7 46.4 40.7 82.5 22.8 DNMT1 "CXXC9, DNMT, MCMT" ENSG00000130816 "DNA methyltransferase 1" P26358 19 10133342-10231286 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Deafness, Disease variant, FDA approved drug targets, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 388.1;Spermatocytes: 229.6;Syncytiotrophoblasts: 323.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002694, CAB005876" Enhanced Supported Nucleoplasm NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "CAB005876: AB_731983, HPA002694: AB_1847810" "unprognostic (3.51e-1)" "unprognostic (1.20e-2)" "unprognostic (1.26e-2)" "unprognostic (1.40e-1)" "unprognostic (3.62e-1)" "unprognostic (7.59e-3)" "prognostic unfavorable (1.46e-4)" "unprognostic (2.90e-1)" "unprognostic (4.23e-3)" "unprognostic (1.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.11e-2)" "unprognostic (1.28e-3)" "unprognostic (7.81e-3)" "unprognostic (1.73e-1)" "unprognostic (8.11e-2)" "unprognostic (1.46e-1)" 7.1 3.9 0.9 16.9 2.9 23.1 7.0 11.7 3.1 9.1 0.0 6.9 6.6 7.3 3.1 7.7 6.5 6.2 4.8 2.1 6.6 3.0 3.9 7.8 26.2 3.8 4.5 5.6 3.6 4.3 4.5 26.0 5.7 4.5 6.8 7.5 5.6 4.6 5.3 7.9 7.9 8.8 0.3 8.1 6.3 12.4 3.3 20.6 6.3 5.0 24.9 7.3 6.4 10.6 77.0 40.6 49.5 45.8 24.6 24.0 138.8 52.4 43.9 77.5 74.9 50.6 40.8 138.3 33.8 30.0 38.6 46.6 68.4 44.2 68.4 57.5 100.9 181.5 39.5 27.1 9.6 91.5 73.4 11.5 9.3 68.5 24.1 18.4 39.9 37.6 75.0 82.8 63.3 37.6 109.2 50.4 87.5 38.3 76.6 117.1 67.9 77.2 21.5 49.3 64.5 41.5 58.2 26.2 16.5 33.6 28.9 42.2 31.8 111.3 42.2 73.0 84.4 49.6 69.5 166.8 35.0 68.5 87.1 20.3 21.2 5.9 29.8 22.0 25.1 14.2 22.8 20.4 19.3 20.0 25.5 20.5 4.6 42.6 13.8 31.9 21.9 12.6 0.9 2.9 11.7 3.1 2.1 6.6 3.8 4.5 5.7 0.3 3.3 10.6 36.4 6.4 26.5 12.7 38.0 29.6 20.7 26.8 21.1 86.7 32.6 29.6 14.6 7.2 28.2 22.0 56.3 388.1 54.4 29.0 13.7 26.0 46.1 48.1 42.0 38.9 15.7 109.6 17.6 14.3 73.2 33.6 33.6 60.3 37.2 43.6 25.0 14.8 76.8 65.6 22.6 25.5 38.7 31.4 47.8 50.8 28.0 57.9 14.2 15.0 52.5 32.2 123.6 14.6 20.1 21.1 11.3 28.6 73.4 16.3 4.5 9.3 42.8 50.2 13.1 22.6 32.8 229.6 145.3 41.6 22.4 323.7 70.4 38.7 43.1 16.6 DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 93.6;lymphoid tissue: 118.4" "Group enriched" "Detected in many" 5 "B-cells: 31.6;granulocytes: 18.3;Hofbauer cells: 55.7;Kupffer cells: 51.1;Macrophages: 38.3;monocytes: 45.4;Plasma cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.6" "Group enriched" "Detected in many" 6 "B-cells: 37.2;granulocytes: 133.6;monocytes: 77.6" "Cell line enhanced" "Detected in many" "Daudi: 124.0;HMC-1: 87.5;REH: 148.6;U-698: 122.1;U-937: 88.0" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: AB_2732339" "unprognostic (2.21e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.34e-3)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.82e-11)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.0 6.1 5.2 30.2 6.2 93.6 4.4 6.5 7.9 3.2 6.3 8.2 6.5 3.4 1.7 5.5 7.8 4.3 4.1 6.0 7.0 5.0 6.5 27.1 31.5 11.3 6.8 2.1 4.5 0.8 3.4 7.0 10.5 5.5 3.5 2.1 6.6 2.0 3.6 2.6 28.9 4.5 6.7 118.4 5.9 8.9 9.9 4.3 4.4 4.1 32.3 7.1 4.0 8.1 5.2 7.8 5.4 6.3 3.2 0.4 13.0 4.4 1.1 14.0 12.9 11.0 2.2 124.0 3.2 4.0 6.8 8.9 12.2 7.6 6.9 26.1 14.6 21.3 21.4 2.5 1.0 46.1 87.5 1.6 4.5 16.2 1.6 1.5 1.9 11.4 14.8 50.2 5.1 12.9 2.7 52.5 12.2 1.5 12.9 148.6 9.3 1.2 4.4 5.2 7.4 4.9 2.0 2.1 6.2 4.8 11.7 63.4 2.7 12.3 11.3 6.5 5.4 11.1 15.0 122.1 2.7 88.0 2.2 16.8 62.4 57.0 0.3 61.3 0.6 37.2 0.1 0.3 14.5 19.6 0.1 0.1 133.6 0.5 77.6 1.2 0.0 28.7 5.2 6.2 6.5 7.9 6.0 7.0 11.3 6.8 10.5 6.7 9.9 8.1 1.4 0.0 5.6 1.6 31.6 0.3 0.1 0.4 1.8 0.8 1.0 0.9 0.4 0.0 0.2 0.0 0.0 0.5 0.3 0.2 0.0 0.2 0.0 0.4 0.4 1.9 0.0 6.3 4.1 0.2 0.7 1.2 0.5 0.8 18.3 0.2 7.1 0.8 55.7 0.0 3.5 0.3 0.0 51.1 2.3 0.4 0.6 38.3 1.8 3.7 45.4 0.3 2.1 0.5 0.5 0.0 0.7 1.2 38.3 0.2 0.2 0.1 0.1 0.6 0.0 1.8 0.4 3.0 1.9 0.7 0.3 1.0 2.2 0.3 0.8 0.1 DOT1L "DOT1, KIAA1814, KMT4" ENSG00000104885 "DOT1 like histone lysine methyltransferase" Q8TEK3 19 2163933-2232578 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 99.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011875, HPA071217, HPA074977" Uncertain Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA011875: AB_2668552, HPA071217: AB_2686364, HPA074977: " "unprognostic (1.41e-2)" "unprognostic (1.44e-1)" "unprognostic (2.26e-1)" "prognostic favorable (1.69e-4)" "unprognostic (1.08e-1)" "prognostic favorable (6.00e-4)" "unprognostic (2.53e-3)" "unprognostic (2.21e-1)" "unprognostic (1.57e-2)" "unprognostic (1.67e-2)" "unprognostic (5.25e-3)" "unprognostic (8.18e-3)" "unprognostic (2.56e-1)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" 11.4 12.9 3.7 10.5 7.6 22.1 8.9 9.9 9.1 8.8 4.9 12.1 12.5 10.0 1.1 14.7 8.6 5.2 9.7 5.1 3.7 19.7 15.1 18.3 8.0 7.5 4.9 10.5 15.4 2.0 13.9 5.4 6.2 9.7 3.9 8.5 9.9 1.9 12.2 14.5 17.6 3.4 1.7 17.3 12.7 99.7 7.9 7.0 15.6 2.8 5.0 7.2 9.8 11.2 27.7 14.4 48.4 26.5 3.5 5.2 63.5 15.2 3.4 8.3 6.6 18.4 10.1 31.6 7.3 10.0 7.0 24.0 16.1 8.6 3.9 16.4 20.0 29.6 26.7 18.3 5.5 42.8 52.6 5.0 6.3 15.9 8.1 6.8 6.7 17.8 36.2 32.7 6.6 15.6 34.1 46.4 37.4 17.4 25.2 34.8 13.6 21.8 4.6 12.9 31.9 24.7 10.7 31.8 20.2 12.7 14.3 32.4 9.6 22.9 20.7 34.2 30.1 29.9 42.8 22.0 22.6 28.6 13.7 0.1 0.1 0.8 0.2 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.2 0.2 0.0 0.2 3.7 7.6 9.9 9.1 5.1 3.7 7.5 4.9 6.2 1.7 7.9 11.2 9.3 32.1 16.3 12.4 9.5 17.7 14.7 4.7 10.2 27.2 12.7 8.4 7.1 11.5 7.2 9.2 66.7 6.1 15.9 29.1 3.9 11.5 37.6 14.2 10.7 10.2 20.8 8.6 7.8 12.2 13.8 11.0 27.5 28.2 6.3 15.9 5.3 14.4 9.9 13.5 6.8 12.0 4.1 12.3 30.4 18.2 3.1 19.0 12.4 10.3 8.5 5.5 8.2 10.6 15.0 13.9 28.6 3.4 8.6 12.9 35.6 3.1 7.6 28.1 0.0 14.2 10.3 32.4 23.0 12.2 19.9 16.3 6.3 15.3 15.9 15.3 DPEP2 ENSG00000167261 "Dipeptidase 2" Q9H4A9 16 67987394-68000586 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.3;lymphoid tissue: 28.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 29.9;Kupffer cells: 55.0;Macrophages: 34.6;monocytes: 28.6;NK-cells: 25.7;Syncytiotrophoblasts: 54.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 410.0;eosinophil: 841.1;neutrophil: 358.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 841.1" "Cell line enhanced" "Detected in some" "HEL: 4.1;HMC-1: 18.1;NB-4: 4.1;U-937: 6.3" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 12.3" HPA035644 Approved NA NA 330000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA035644: AB_10670164" "unprognostic (8.81e-2)" "unprognostic (7.84e-5)" "unprognostic (1.35e-1)" "unprognostic (1.42e-2)" "unprognostic (1.92e-1)" "unprognostic (6.66e-3)" "unprognostic (1.03e-1)" "unprognostic (5.47e-2)" "unprognostic (3.69e-2)" "unprognostic (1.68e-1)" "unprognostic (6.01e-2)" "unprognostic (1.46e-1)" "unprognostic (3.91e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (7.78e-3)" "unprognostic (3.91e-2)" 6.0 0.9 4.3 12.6 4.4 23.3 2.8 4.3 9.3 2.3 4.1 4.1 3.3 1.4 0.6 1.8 2.8 6.2 2.4 4.1 4.8 1.8 3.8 18.5 18.8 6.3 4.9 0.6 1.0 0.9 0.7 13.4 5.1 1.5 4.1 0.2 1.7 1.2 1.4 1.2 11.9 4.0 5.1 28.6 3.2 2.8 5.6 9.0 2.5 3.3 18.3 8.1 1.3 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.2 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.5 0.0 4.1 0.0 0.1 0.0 0.1 18.1 0.0 0.1 0.0 0.0 0.1 0.1 1.3 0.3 0.1 0.0 0.0 0.1 4.1 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.5 0.0 0.0 0.0 0.0 1.0 0.5 0.3 0.0 6.3 0.0 410.0 82.6 841.1 17.0 101.9 19.8 30.3 29.5 13.7 33.0 35.9 34.7 17.8 358.8 44.7 126.7 5.3 31.8 48.9 4.3 4.4 4.3 9.3 4.1 4.8 6.3 4.9 5.1 5.1 5.6 6.6 0.9 0.0 7.9 0.0 20.4 2.0 0.0 0.3 1.2 0.0 0.2 0.3 1.8 0.0 1.7 0.0 0.0 10.0 8.7 0.1 0.0 0.1 0.2 0.1 0.1 4.8 0.0 2.1 0.1 0.0 0.7 1.0 0.5 0.1 2.5 0.0 18.9 0.1 29.9 0.0 0.2 0.0 2.0 55.0 21.0 1.1 0.0 34.6 3.6 10.3 28.6 0.0 25.7 0.0 0.1 0.0 0.0 0.4 3.4 0.0 0.0 0.3 8.6 0.0 0.0 0.3 0.8 12.0 9.4 0.1 1.3 54.0 13.1 0.0 0.0 0.1 DPF3 "BAF45c, cer-d4, Cerd4, FLJ14079" ENSG00000205683 "Double PHD fingers 3" Q92784 14 72619296-72894116 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.5;retina: 18.0;skeletal muscle: 26.5" "Cell type enhanced" "Detected in many" "Astrocytes: 104.5;Cone photoreceptor cells: 108.4;Early spermatids: 58.5;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 115.7;Rod photoreceptor cells: 85.5" "Cancer enhanced" "Detected in some" "glioma: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;BJ hTERT+ SV40 Large T+: 12.2;HEL: 31.5;Karpas-707: 12.4" "Region enhanced" "Detected in all" "cerebellum: 49.5" "Low region specificity" "Detected in all" "HPA066790, HPA070601" Enhanced Enhanced Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA066790: AB_2685724, HPA070601: AB_2686284" "unprognostic (2.38e-2)" "unprognostic (2.96e-1)" "unprognostic (3.25e-1)" "unprognostic (1.56e-2)" "unprognostic (1.55e-1)" "unprognostic (9.98e-2)" "unprognostic (4.80e-2)" "unprognostic (1.19e-2)" "unprognostic (1.33e-1)" "unprognostic (3.54e-2)" "unprognostic (9.71e-3)" "unprognostic (1.02e-1)" "unprognostic (2.02e-1)" "unprognostic (3.85e-3)" "unprognostic (4.08e-2)" "unprognostic (4.80e-2)" "unprognostic (1.96e-1)" 0.3 1.4 2.8 0.5 6.7 2.6 0.4 35.5 5.1 0.4 0.0 2.0 0.2 0.2 0.0 0.6 0.3 0.3 14.2 10.2 3.8 1.4 3.0 0.2 0.8 12.0 5.9 13.7 0.3 5.1 0.6 0.3 12.6 0.1 1.5 18.0 0.4 0.2 26.5 0.5 1.3 0.5 4.4 1.0 0.5 3.5 5.7 0.3 0.4 9.1 1.0 0.2 0.2 7.7 2.1 0.0 1.6 0.1 0.2 2.9 17.7 5.4 5.1 12.2 4.7 0.1 0.2 0.2 0.3 1.7 0.2 0.1 1.7 0.8 7.4 0.3 0.6 31.5 0.2 0.0 0.5 0.2 0.5 0.7 0.3 2.8 2.0 2.0 4.0 3.4 2.8 12.4 3.9 0.1 2.7 0.3 0.0 0.0 1.8 6.9 0.8 0.4 2.1 0.0 1.2 0.7 0.0 0.1 0.0 0.5 0.0 0.0 8.7 6.0 0.0 2.2 0.6 4.3 1.2 0.4 0.5 1.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 6.7 35.5 5.1 10.2 3.8 12.0 5.9 12.6 4.4 5.7 7.7 0.8 0.0 0.0 104.5 6.0 0.6 0.1 0.0 0.0 10.5 1.1 0.9 38.4 1.5 0.0 0.0 108.4 2.6 2.6 7.5 1.9 0.1 58.5 0.1 0.8 2.9 0.0 8.6 17.7 0.4 1.3 2.8 0.0 0.1 4.5 43.2 1.1 4.4 0.4 6.7 21.7 3.4 0.0 0.8 0.7 34.3 0.3 1.7 0.0 8.4 0.1 8.6 2.1 123.1 115.7 0.7 5.1 4.9 2.6 0.1 2.7 10.7 0.0 85.5 0.0 2.6 3.5 4.5 1.2 0.3 0.3 0.1 3.8 14.5 7.4 0.0 DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992245-162074394 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 137.9;parathyroid gland: 155.7;placenta: 134.1;prostate: 107.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 140.3;Proximal enterocytes: 291.1;Proximal tubular cells: 101.4;Syncytiotrophoblasts: 172.0" "Cancer enhanced" "Detected in all" "prostate cancer: 55.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 52.3" "Lineage enriched" "Detected in many" 10 "T-cells: 52.3" "Cell line enhanced" "Detected in many" "ASC diff: 194.4;ASC TERT1: 212.6;BJ hTERT+: 207.0;RPTEC TERT1: 263.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045970, HPA068778, HPA071236" Enhanced "Secreted to blood" NA NA 190000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB045970: AB_11140529, HPA068778: , HPA071236: " "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.98e-4)" "prognostic favorable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favorable (4.99e-4)" "unprognostic (1.21e-2)" 13.3 3.1 0.2 5.3 0.2 0.6 8.4 0.1 0.6 10.9 0.1 14.6 107.0 3.6 4.0 3.0 7.4 6.7 3.4 0.2 0.1 94.9 57.2 16.0 5.8 0.2 0.2 3.5 3.5 155.7 0.1 134.1 0.3 107.3 16.9 0.1 84.5 23.5 1.5 5.7 137.9 3.0 0.1 11.2 7.6 1.3 0.8 12.4 5.0 3.9 4.4 5.7 3.5 0.4 0.2 0.2 1.0 0.0 194.4 212.6 0.6 37.7 207.0 10.9 37.2 38.0 1.0 0.0 13.6 71.0 30.2 1.1 0.4 0.0 6.2 12.3 0.0 0.0 0.0 57.1 77.0 0.0 0.0 22.0 0.1 66.3 0.5 9.1 6.6 0.7 0.0 0.0 3.6 0.0 3.6 0.5 2.0 1.3 72.7 0.0 0.0 0.6 263.3 0.0 0.1 0.4 0.0 0.0 0.0 4.4 0.0 0.3 37.0 21.8 1.1 0.7 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 6.6 0.0 52.3 0.2 16.2 10.7 1.2 0.0 15.7 6.6 0.4 5.3 0.0 4.0 2.0 4.7 0.2 0.2 0.1 0.6 0.2 0.1 0.2 0.2 0.3 0.1 0.8 0.4 10.8 6.4 26.0 0.3 2.1 4.1 0.4 0.1 0.0 1.8 0.2 0.8 3.3 12.8 2.8 14.7 10.4 140.3 10.4 27.4 1.9 3.0 15.0 2.3 7.1 9.4 55.2 0.4 31.6 0.0 59.1 35.3 2.0 68.0 13.9 5.3 9.3 34.5 14.5 0.0 6.3 16.4 0.0 0.9 7.6 7.9 0.0 4.8 5.4 3.7 1.1 0.0 1.0 2.5 0.7 1.4 23.8 0.0 2.1 32.7 291.1 101.4 2.2 0.1 0.0 2.1 1.5 4.0 1.1 0.1 4.1 172.0 25.8 29.2 29.1 0.3 DPP7 "DPP2, DPPII" ENSG00000176978 "Dipeptidyl peptidase 7" Q9UHL4 9 137110546-137115177 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 997.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 232.0;THP-1: 218.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021282, CAB025541, HPA059381" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted - unknown location" NA NA 1600000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "CAB025541: , HPA021282: AB_1847673, HPA059381: AB_2683999" "unprognostic (1.15e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (6.07e-6)" "unprognostic (6.78e-3)" "unprognostic (1.25e-1)" "unprognostic (8.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.10e-2)" "unprognostic (2.28e-2)" "unprognostic (5.71e-3)" "prognostic favorable (8.31e-5)" "unprognostic (7.99e-2)" "unprognostic (1.46e-2)" "unprognostic (2.56e-2)" "unprognostic (1.72e-1)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" 60.2 98.8 42.1 28.0 43.2 45.8 56.8 43.4 64.9 45.4 83.6 65.3 28.4 46.3 16.7 46.0 53.6 31.3 116.4 43.8 52.0 58.7 70.0 57.3 41.7 53.4 48.0 37.7 82.8 54.3 112.3 26.7 45.7 81.1 7.3 8.0 92.3 46.2 52.8 56.6 51.7 12.8 45.6 79.0 69.4 75.3 48.3 19.8 83.7 21.4 14.4 59.3 48.0 49.2 28.0 43.1 3.5 3.6 51.1 40.5 5.7 42.2 66.2 26.6 17.4 41.0 22.2 56.2 44.4 27.2 1.2 60.3 30.7 8.2 1.3 54.8 2.1 26.4 63.6 1.3 113.5 69.1 135.5 50.0 31.7 11.6 24.1 38.3 35.1 65.8 57.5 41.2 18.0 76.4 35.7 65.7 14.8 99.9 42.8 52.8 0.5 232.0 43.3 30.5 67.7 46.7 47.8 122.6 118.9 0.8 43.5 218.1 44.1 67.4 23.5 43.4 29.5 51.7 31.8 14.9 80.9 41.1 31.1 40.2 194.8 59.2 148.8 176.2 151.8 86.6 131.4 127.9 190.6 83.4 117.1 106.2 12.0 95.0 110.6 276.6 173.6 204.1 42.1 43.2 43.4 64.9 43.8 52.0 53.4 48.0 45.7 45.6 48.3 49.2 80.5 54.5 80.9 54.9 96.8 67.0 103.2 109.2 59.7 74.5 90.3 82.2 66.5 94.4 76.8 53.3 35.5 55.2 129.2 28.2 37.2 121.0 288.7 35.9 40.7 58.2 88.1 35.9 31.4 68.1 115.3 97.2 33.6 47.3 74.3 178.7 64.6 77.1 315.7 121.1 27.9 32.3 107.8 171.7 106.2 997.8 155.4 150.1 167.2 9.4 165.5 123.9 122.6 16.6 26.4 58.2 54.3 169.2 190.2 108.5 97.3 84.9 75.4 83.6 52.6 57.4 58.4 106.2 46.2 47.3 64.9 51.4 115.4 19.0 43.1 90.4 DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 5 "Fibroblasts: 457.5;Leydig cells: 231.8;Peritubular cells: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 143.3;fHDF/TERT166: 59.9" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" 334.6 39.6 0.4 28.6 0.5 0.0 251.3 0.5 1.0 177.6 0.5 424.7 18.8 63.2 60.8 86.0 129.1 78.0 241.4 0.5 0.4 13.2 29.0 48.6 58.6 0.5 0.4 30.3 84.8 4.9 2.1 37.5 0.6 55.2 58.2 0.0 72.0 52.7 37.1 39.2 94.2 138.5 0.5 0.9 108.5 15.4 0.5 48.0 75.0 209.3 70.1 103.3 166.9 0.7 0.0 0.0 0.0 0.0 143.3 0.6 0.2 0.1 6.7 7.2 7.4 0.0 0.0 0.0 0.0 59.9 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 4.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.6 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.5 1.0 0.5 0.4 0.5 0.4 0.6 0.5 0.5 0.7 18.7 3.2 1.7 0.3 0.3 31.9 0.1 0.0 1.8 0.0 2.2 2.3 7.4 0.0 0.6 0.0 0.0 0.6 0.4 0.1 0.0 0.1 1.2 0.3 10.7 6.9 0.0 0.0 4.8 0.2 0.8 457.5 3.1 0.2 0.0 0.0 8.9 0.0 0.6 0.0 3.4 0.0 0.0 0.0 45.6 4.4 231.8 4.0 39.2 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 123.8 0.5 0.5 0.0 0.1 0.0 0.0 0.0 24.4 18.5 0.5 0.3 3.1 32.0 0.4 5.0 2.2 0.0 0.6 DRAM1 "DRAM, FLJ11259" ENSG00000136048 "DNA damage regulated autophagy modulator 1" Q8N682 12 101877580-102012130 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 94.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 321.8;Early spermatids: 145.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "BJ hTERT+: 532.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (8.82e-2)" "unprognostic (1.80e-1)" "unprognostic (7.19e-2)" "prognostic favorable (6.52e-8)" "unprognostic (1.15e-2)" "unprognostic (2.35e-3)" "unprognostic (1.29e-3)" "unprognostic (1.23e-2)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "unprognostic (6.17e-3)" "unprognostic (5.02e-2)" "prognostic unfavorable (3.91e-4)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (3.58e-2)" "unprognostic (2.07e-2)" 14.9 15.4 3.5 18.9 3.9 36.9 11.3 5.0 4.2 8.9 7.5 10.2 7.0 10.2 5.3 10.7 9.4 16.8 8.3 3.6 4.5 23.7 7.8 94.1 18.2 4.3 3.4 7.3 8.4 6.1 5.9 20.1 3.7 9.1 9.4 4.3 11.1 7.2 4.7 9.0 9.3 12.6 3.2 11.4 15.7 4.9 4.7 9.3 7.4 5.4 10.5 37.2 7.9 5.5 10.6 20.5 7.4 2.3 93.4 21.4 40.4 77.2 532.4 76.2 118.3 6.9 19.8 1.9 8.5 128.2 29.4 15.5 1.9 32.2 104.8 11.3 6.2 2.6 17.5 27.2 43.1 3.0 5.5 25.5 14.0 26.8 28.7 65.1 41.5 2.4 9.5 3.6 20.0 8.3 1.8 9.0 5.1 26.3 4.9 3.4 5.4 1.9 80.9 49.4 1.4 1.6 42.8 4.8 20.5 20.3 14.9 11.7 25.3 53.3 9.5 9.3 14.2 10.7 5.3 1.4 17.9 26.8 14.2 10.2 9.0 6.0 1.6 10.2 2.0 2.7 1.3 1.8 3.1 1.4 0.9 1.1 8.6 3.3 5.8 0.8 1.9 2.8 3.5 3.9 5.0 4.2 3.6 4.5 4.3 3.4 3.7 3.2 4.7 5.5 17.2 54.5 321.8 4.9 10.7 20.9 21.5 42.4 28.5 1.6 12.8 8.0 4.3 10.0 25.2 29.5 0.0 28.1 5.0 1.3 1.9 11.4 145.0 12.7 30.8 16.5 0.0 11.3 0.5 21.4 30.9 30.5 10.2 15.6 24.1 3.2 10.0 2.0 60.6 0.0 4.7 1.6 14.2 40.5 31.1 80.6 14.0 51.9 8.8 3.7 24.6 3.2 5.2 10.1 0.6 21.7 0.3 10.5 30.9 34.2 0.3 23.4 7.4 0.2 13.1 14.4 9.9 1.2 4.5 3.2 6.1 22.0 6.4 7.3 1.2 22.1 DRAXIN "C1orf187, FLJ34999, Neucrin" ENSG00000162490 "Dorsal inhibitory axon guidance protein" Q8NBI3 1 11691710-11725857 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 3.9" "Cell type enhanced" "Detected in some" "dendritic cells: 5.5;NK-cells: 3.1;T-cells: 4.6" "Group enriched" "Detected in some" 6 "glioma: 5.1;testis cancer: 2.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 2.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.5" "Cell line enriched" "Detected in some" 4 "NTERA-2: 27.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA014302 Uncertain "Secreted in brain" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 63: NK-cells & T-cells - Immune response" "HPA014302: AB_1853084" "unprognostic (5.28e-2)" "unprognostic (2.73e-1)" "unprognostic (6.58e-2)" "unprognostic (4.95e-2)" "unprognostic (2.51e-1)" "unprognostic (1.85e-1)" "unprognostic (1.37e-2)" "unprognostic (1.84e-2)" "unprognostic (1.49e-1)" "unprognostic (1.17e-1)" "unprognostic (1.51e-2)" "unprognostic (7.47e-2)" "unprognostic (5.16e-6)" "unprognostic (4.65e-2)" "unprognostic (1.15e-1)" "unprognostic (8.52e-2)" "unprognostic (5.08e-1)" 0.0 0.0 1.6 0.2 1.4 0.5 0.0 1.1 1.3 0.0 0.6 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.0 1.2 1.0 0.0 0.0 0.1 0.2 2.7 0.6 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.7 0.0 0.1 0.2 0.1 0.0 0.4 0.1 0.0 0.3 3.9 0.0 0.1 0.0 0.1 0.0 0.0 1.3 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.6 0.0 0.9 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 5.7 0.0 0.2 0.0 0.1 0.0 0.2 2.1 0.3 27.9 0.0 0.1 6.4 0.2 0.0 0.0 0.0 1.8 0.7 0.1 0.0 0.1 4.6 0.0 0.2 0.2 0.1 1.2 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.4 2.5 0.3 0.1 0.5 0.1 0.2 0.1 0.1 0.3 0.0 0.2 0.2 0.2 0.8 0.2 0.2 0.1 0.2 0.1 1.6 1.4 1.1 1.3 1.2 1.0 2.7 0.6 0.5 0.4 3.9 1.3 0.1 0.0 0.5 0.0 1.2 0.5 2.9 0.6 0.0 0.7 0.4 0.4 1.1 1.5 0.1 0.0 2.1 0.1 5.5 0.1 0.0 0.1 0.7 0.4 0.4 0.6 0.0 0.0 0.4 0.2 0.2 0.6 0.0 0.4 1.3 0.1 1.1 0.2 0.4 0.0 0.5 0.7 0.0 0.8 1.9 2.1 0.6 1.2 1.8 0.0 0.3 0.2 3.1 1.5 0.4 0.2 0.2 0.0 1.5 2.1 0.0 0.1 0.0 0.7 0.0 2.3 0.7 0.6 1.7 0.0 0.3 0.0 4.6 0.1 0.1 2.2 DSE "DS-Epi1, DSEPI, SART2" ENSG00000111817 "Dermatan sulfate epimerase" Q9UL01 6 116254173-116444861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 112.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 5.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014764 Uncertain "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "HPA014764: AB_1856587" "unprognostic (1.28e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (3.23e-3)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.02e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (6.34e-4)" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.19e-3)" "unprognostic (2.54e-2)" "unprognostic (2.06e-1)" "unprognostic (1.10e-2)" 27.8 10.7 3.6 26.8 4.5 18.4 18.3 3.9 4.4 13.8 10.4 7.7 6.4 10.5 8.3 13.7 14.6 14.9 12.4 3.2 4.3 8.6 11.3 15.3 16.4 7.0 5.8 13.8 3.8 11.1 6.0 23.1 5.6 8.5 8.0 3.5 6.9 10.2 6.9 13.8 9.0 15.0 4.6 18.6 6.4 6.1 8.5 10.3 6.6 10.7 9.7 19.7 14.3 5.9 32.7 7.0 23.6 22.2 62.0 40.7 26.5 37.6 88.2 46.4 67.4 0.2 8.9 0.9 3.3 66.3 46.4 60.8 3.3 88.7 60.1 33.9 14.6 2.2 9.8 0.3 69.0 1.5 1.7 86.8 37.4 51.5 50.0 24.0 27.7 8.3 0.8 14.4 22.4 1.0 4.4 1.8 12.7 0.2 1.8 5.6 21.6 15.6 30.4 2.2 7.8 5.9 36.4 0.1 0.8 16.2 0.3 3.9 10.5 46.4 13.4 11.8 30.6 3.1 1.1 1.6 24.6 4.0 5.5 0.4 2.0 0.1 0.6 2.5 0.3 2.0 0.5 0.3 5.9 2.1 0.6 0.3 1.6 0.1 1.6 2.7 0.1 0.8 3.6 4.5 3.9 4.4 3.2 4.3 7.0 5.8 5.6 4.6 8.5 5.9 9.4 16.0 4.1 64.9 15.4 52.0 26.4 42.2 78.6 6.3 7.4 10.7 8.3 2.8 20.7 3.7 0.0 2.9 16.5 0.3 7.9 4.8 52.2 11.0 21.9 15.4 1.2 11.4 46.8 8.5 7.0 73.7 3.6 3.1 22.8 100.9 56.4 5.7 39.8 1.7 48.9 0.6 8.2 83.6 77.1 24.9 55.0 112.2 10.6 51.5 79.4 3.4 5.2 73.4 86.4 13.6 0.4 30.1 8.9 32.0 0.4 7.7 30.3 3.0 32.9 16.4 33.4 6.1 5.5 76.6 39.9 4.9 14.0 17.2 1.0 51.0 DSG2 CDHF5 ENSG00000046604 "Desmoglein 2" Q14126 18 31498177-31549008 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 105.3;parathyroid gland: 157.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.6;Pancreatic endocrine cells: 254.9;Undifferentiated cells: 216.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "basophil: 8.4" "Lineage enriched" "Detected in single" 13 "granulocytes: 8.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 172.9;HaCaT: 269.2;HBEC3-KT: 201.2;hTERT-HME1: 212.1;OE19: 229.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA004896, CAB025122" Enhanced Supported "Cell Junctions" NA NA 140000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "CAB025122: , HPA004896: AB_1078643" "unprognostic (1.56e-3)" "prognostic unfavorable (8.22e-4)" "prognostic favorable (7.81e-4)" "unprognostic (8.77e-3)" "unprognostic (3.53e-4)" "prognostic unfavorable (5.63e-4)" "unprognostic (2.86e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (5.21e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (4.94e-5)" "unprognostic (3.40e-1)" "prognostic favorable (3.14e-10)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-1)" "unprognostic (8.57e-3)" 23.6 1.2 0.2 14.6 0.2 0.8 40.2 0.6 0.2 13.0 26.4 105.3 79.1 8.6 10.6 10.2 22.4 31.4 31.4 0.7 0.1 33.8 15.1 15.0 1.6 0.3 0.5 13.6 39.5 157.8 1.6 22.9 0.7 31.5 100.0 0.3 68.6 6.5 1.2 6.7 84.6 7.3 0.0 0.4 77.1 3.7 0.4 24.2 42.2 0.7 4.6 41.6 5.7 0.5 119.2 45.3 4.0 0.1 0.6 7.2 143.0 0.0 0.0 0.3 0.0 31.7 172.9 0.0 64.2 0.0 54.4 269.2 54.7 201.2 0.0 0.2 33.9 0.1 46.7 35.9 20.2 15.2 0.3 9.9 136.7 4.2 212.1 102.4 0.0 34.7 47.8 0.2 0.0 31.5 32.2 2.0 55.4 229.5 23.1 52.8 0.0 76.2 65.8 58.5 23.9 0.2 88.3 61.8 0.3 117.8 44.3 12.7 0.1 0.2 25.0 0.3 29.3 5.7 0.2 0.2 19.8 0.1 25.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.2 0.6 0.2 0.7 0.1 0.3 0.5 0.7 0.0 0.4 0.5 120.8 54.5 45.4 0.0 1.3 13.5 79.4 76.2 28.5 0.4 68.9 49.3 57.3 101.5 79.6 12.9 0.0 80.1 4.4 404.6 3.9 105.5 1.0 48.6 9.4 13.1 79.9 9.0 3.3 76.1 116.2 12.0 70.3 82.1 4.5 18.8 2.2 26.4 10.3 1.7 0.3 165.7 79.3 0.8 4.0 2.5 1.5 2.2 17.8 0.0 6.3 5.3 1.0 0.5 0.1 254.9 152.0 0.4 0.3 133.5 145.1 10.0 75.4 0.7 0.0 0.6 8.2 2.7 8.9 23.1 6.0 59.9 2.6 6.6 216.8 179.9 DSN1 "C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13" ENSG00000149636 "DSN1 component of MIS12 kinetochore complex" Q9H410 20 36751791-36773818 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 49.8;Spermatocytes: 115.5;Spermatogonia: 75.1;Syncytiotrophoblasts: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002813, HPA030627" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Kinetochore,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies, Kinetochore, Cytosol" "HPA002813: AB_1078343, HPA030627: AB_2732460" "unprognostic (3.60e-2)" "prognostic favorable (4.49e-4)" "unprognostic (5.22e-3)" "unprognostic (1.13e-3)" "unprognostic (2.00e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (4.16e-5)" "unprognostic (3.93e-1)" "unprognostic (9.35e-2)" "unprognostic (5.51e-2)" "unprognostic (2.98e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.92e-2)" "unprognostic (2.53e-1)" "unprognostic (2.58e-2)" "unprognostic (2.84e-1)" 5.9 9.9 4.2 7.5 4.2 14.3 8.6 3.9 4.5 5.0 5.2 9.2 6.8 4.4 9.3 7.9 4.1 4.4 5.1 4.3 4.4 4.8 9.1 6.3 12.8 4.0 3.9 4.3 4.3 5.5 3.5 8.8 4.1 6.5 10.8 10.7 5.9 6.3 4.0 8.0 7.8 6.3 3.9 9.6 7.3 23.3 4.1 16.4 5.1 4.8 14.3 4.4 4.7 4.7 36.7 29.1 35.7 29.5 14.0 18.0 24.7 42.9 35.1 63.9 70.2 52.5 44.4 39.3 27.4 23.0 69.1 45.8 33.3 32.7 60.3 18.2 22.7 78.3 26.2 36.1 3.0 46.2 34.0 7.0 9.4 43.7 13.8 10.4 31.5 42.4 30.9 33.7 41.7 25.3 59.2 34.5 16.8 63.3 55.1 46.1 109.4 28.4 16.2 20.5 37.8 16.9 52.9 53.7 25.8 26.3 55.9 30.5 16.4 60.1 35.0 56.9 46.1 27.3 39.1 46.4 49.8 40.8 42.6 53.4 6.4 14.5 7.4 11.0 8.4 14.6 8.1 10.3 7.1 18.4 10.1 9.0 11.9 11.1 10.1 46.9 12.2 6.7 4.2 4.2 3.9 4.5 4.3 4.4 4.0 3.9 4.1 3.9 4.1 4.7 6.5 6.4 4.4 1.6 10.3 5.0 11.4 7.6 3.4 8.0 8.7 7.6 5.4 2.8 8.6 5.5 29.2 49.8 9.8 9.2 7.9 6.8 10.6 5.5 5.9 8.1 2.4 22.1 6.3 6.4 30.4 8.4 20.9 9.4 3.8 21.8 7.9 6.2 14.7 6.7 4.4 13.6 4.1 6.3 4.6 8.0 8.7 6.7 1.8 5.6 7.4 6.0 7.2 3.0 3.6 5.1 5.4 7.5 22.9 7.1 7.7 3.6 8.2 17.5 0.0 5.3 8.2 115.5 75.1 12.3 7.2 47.5 7.7 6.9 13.6 11.0 DSPP "DFNA39, DGI1, DMP3" ENSG00000152591 "Dentin sialophosphoprotein" Q9NZW4 4 87608529-87616873 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Deafness, Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036230 Uncertain "Secreted in other tissues" NA NA 27000 "HPA036230: AB_10672239" "unprognostic (2.34e-1)" "unprognostic (1.08e-2)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" "unprognostic (2.21e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DST "BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2" ENSG00000151914 Dystonin Q03001 6 56457987-56954830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Cancer-related genes, Epidermolysis bullosa, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2368.6;Basal prostatic cells: 1651.4;Basal squamous epithelial cells: 3008.4;Cone photoreceptor cells: 1401.1;Oligodendrocytes: 1410.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTCEpi: 488.1;hTERT-HME1: 371.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030200 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA 16000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Microtubules" Cytosol "HPA030200: AB_10601901" "unprognostic (4.87e-3)" "unprognostic (1.29e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "unprognostic (3.60e-2)" "unprognostic (5.78e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-2)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (4.39e-2)" "unprognostic (5.13e-3)" "unprognostic (1.46e-1)" "unprognostic (2.66e-1)" "unprognostic (7.62e-2)" 60.9 86.2 206.5 16.2 275.8 3.3 117.3 240.6 221.9 158.8 143.3 173.2 25.4 167.1 38.2 66.1 103.9 32.6 166.0 194.6 230.7 52.2 80.8 108.0 11.3 258.1 250.4 78.2 39.8 36.7 78.8 28.7 263.4 84.5 32.4 87.4 100.3 48.7 143.1 166.2 64.2 106.0 209.1 36.7 68.9 28.4 243.3 31.4 29.8 104.1 15.2 90.4 113.2 325.4 62.4 26.6 41.2 20.8 79.5 103.5 24.6 82.2 89.7 37.8 42.1 17.1 15.5 10.4 32.2 220.7 35.6 46.7 34.4 161.2 73.0 52.3 45.2 17.8 49.5 31.4 65.9 15.0 0.4 58.3 488.1 92.5 371.6 69.1 73.3 9.5 12.6 38.2 113.9 20.2 5.1 6.8 27.7 35.6 21.9 0.1 28.8 16.5 118.8 83.0 47.2 37.8 32.7 11.7 64.1 67.7 18.6 27.2 176.5 77.3 55.9 37.0 68.9 39.6 28.6 5.0 55.8 8.8 40.3 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.9 0.3 1.3 0.0 0.1 206.5 275.8 240.6 221.9 194.6 230.7 258.1 250.4 263.4 209.1 243.3 325.4 193.2 336.5 11.8 1048.7 5.6 2368.6 1651.4 250.1 3008.4 673.1 81.0 301.5 862.8 77.2 161.7 55.2 1401.1 61.5 7.8 357.8 7.9 204.3 53.6 133.8 218.4 122.7 44.9 12.4 550.4 66.3 11.6 212.5 71.9 166.8 17.1 478.7 60.7 80.3 21.8 307.9 591.7 100.3 118.0 74.2 124.6 15.5 133.3 56.6 215.3 215.5 46.6 200.8 2.1 630.3 1410.3 194.1 283.0 152.4 27.2 229.8 124.2 10.3 52.0 122.6 65.7 381.8 196.6 20.0 13.7 298.2 857.2 26.5 19.7 30.5 48.1 142.8 DUOX1 "LNOX1, NOXEF1, THOX1" ENSG00000137857 "Dual oxidase 1" Q9NRD9 15 45129933-45165576 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 108.5;skin 1: 81.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 83.3;Alveolar cells type 2: 168.6;Endometrial ciliated cells: 67.1;Glandular and luminal cells: 88.5;Respiratory ciliated cells: 64.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.4" "Group enriched" "Detected in many" 6 "cerebellum: 12.4;white matter: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 64.4;hTCEpi: 30.5;RT4: 36.3" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "cerebellum: 9.6" HPA023544 Approved NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA023544: AB_1847878" "unprognostic (2.85e-2)" "prognostic favorable (4.31e-6)" "unprognostic (2.49e-2)" "unprognostic (8.84e-3)" "unprognostic (1.44e-2)" "unprognostic (3.27e-2)" "unprognostic (1.23e-1)" "unprognostic (2.57e-2)" "unprognostic (5.87e-2)" "unprognostic (6.02e-3)" "unprognostic (5.13e-2)" "unprognostic (1.19e-1)" "unprognostic (8.91e-3)" "unprognostic (2.23e-1)" "unprognostic (3.06e-2)" "unprognostic (1.14e-2)" "unprognostic (3.03e-1)" 1.5 14.1 0.7 1.0 1.0 0.2 4.5 12.4 1.2 44.5 0.0 1.0 0.6 3.0 50.0 108.5 14.0 3.3 3.3 1.0 0.3 0.7 0.4 70.1 0.3 0.3 0.3 1.8 0.5 5.2 1.3 1.5 0.6 13.8 0.3 0.6 18.7 13.0 0.4 81.7 0.7 0.4 0.1 0.3 64.3 1.6 0.4 1.1 70.4 0.0 14.7 11.1 42.0 3.2 8.3 0.1 0.5 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 64.4 0.0 6.1 0.0 0.8 0.4 0.0 0.9 0.1 0.0 0.0 0.3 0.0 30.5 0.0 1.9 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.2 0.1 0.0 0.0 36.3 0.8 1.5 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 1.0 12.4 1.2 1.0 0.3 0.3 0.3 0.6 0.1 0.4 3.2 0.9 83.3 168.6 4.2 4.5 11.1 14.3 22.8 11.4 21.3 4.7 2.8 2.4 8.6 32.5 3.7 8.4 5.3 7.6 2.5 0.0 3.8 0.7 67.1 9.4 3.8 21.7 2.7 5.1 5.4 0.6 5.1 17.9 88.5 8.2 7.9 7.9 1.5 1.2 6.7 3.9 4.0 16.2 3.1 43.5 0.3 3.4 3.3 16.0 1.0 3.2 3.5 33.0 9.5 10.6 4.7 4.0 3.8 0.1 9.5 6.8 0.5 64.9 4.4 0.0 8.5 4.7 11.5 7.5 36.4 18.0 3.7 4.5 0.4 5.6 30.0 DYNC2I2 "bA216B9.3, CFAP133, DIC5, FAP133, MGC20486, WDR34" ENSG00000119333 "Dynein 2 intermediate chain 2" Q96EX3 9 128633653-128656847 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 20.4;Cytotrophoblasts: 89.8;Extravillous trophoblasts: 95.3;Hofbauer cells: 21.9;Syncytiotrophoblasts: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 35.8;naive B-cell: 52.9" "Lineage enriched" "Detected in all" 5 "B-cells: 52.9" "Cell line enhanced" "Detected in all" "MCF7: 432.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040764, HPA041091" Approved Approved Cytosol NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA040764: AB_10795625, HPA041091: AB_10796237" "unprognostic (1.45e-1)" "prognostic favorable (1.63e-4)" "unprognostic (2.55e-1)" "prognostic favorable (7.01e-5)" "unprognostic (2.27e-1)" "unprognostic (7.00e-3)" "prognostic unfavorable (8.79e-4)" "unprognostic (6.04e-2)" "unprognostic (4.39e-1)" "unprognostic (3.65e-1)" "unprognostic (8.55e-2)" "unprognostic (1.04e-1)" "unprognostic (3.57e-3)" "unprognostic (2.06e-2)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" 14.4 49.9 15.7 11.4 15.4 33.2 20.1 14.3 20.1 28.2 30.5 26.7 22.2 22.4 8.9 37.9 30.5 11.1 41.4 15.4 18.9 61.8 39.1 25.1 12.0 17.0 19.4 19.1 36.7 21.2 36.1 11.0 16.4 31.0 10.3 4.5 31.9 14.0 11.1 24.0 27.7 6.3 16.5 23.6 26.3 69.8 16.6 23.8 55.6 4.3 9.5 19.2 23.7 14.7 112.7 202.8 49.8 78.8 11.4 16.1 141.4 46.2 32.9 66.5 42.8 96.6 197.3 40.4 32.4 30.8 62.0 169.4 47.5 50.8 16.6 93.5 40.1 24.0 134.8 52.0 13.9 41.5 39.4 8.0 25.0 66.3 18.9 24.0 46.5 112.6 83.5 34.0 36.4 432.4 151.3 106.1 63.7 97.3 121.0 157.2 66.6 136.8 42.1 36.0 125.1 100.1 143.9 135.9 36.8 13.7 230.5 40.7 28.3 75.9 114.8 95.6 90.7 34.6 100.7 39.6 71.4 41.9 74.0 1.7 1.1 0.4 1.4 1.6 2.3 35.8 2.9 3.9 2.8 52.9 1.1 1.7 0.8 4.5 5.7 11.0 5.7 3.8 15.7 15.4 14.3 20.1 15.4 18.9 17.0 19.4 16.4 16.5 16.6 14.7 2.7 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 89.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 95.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 37.4 0.2 0.0 0.0 0.0 DYNLRB1 "DNCL2A, DNLC2A, ROBLD1" ENSG00000125971 "Dynein light chain roadblock-type 1" Q9NP97 20 34516414-34540958 "Plasma proteins, Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 781.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009845 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "CAB009845: AB_2093671" "unprognostic (2.23e-1)" "unprognostic (7.60e-3)" "unprognostic (5.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (6.44e-4)" "unprognostic (9.10e-2)" "unprognostic (3.41e-2)" "unprognostic (7.79e-2)" "unprognostic (1.71e-1)" "unprognostic (2.11e-1)" "unprognostic (7.55e-2)" "unprognostic (1.32e-1)" "unprognostic (3.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.00e-1)" 168.7 208.4 430.4 96.9 440.2 113.7 163.7 416.5 552.8 163.7 400.8 228.4 113.8 193.0 204.9 155.4 198.5 117.1 275.7 448.5 454.1 265.8 122.0 169.4 123.9 444.7 443.3 153.9 115.0 222.9 204.3 154.6 436.7 180.9 128.2 171.7 142.1 170.7 222.8 222.1 156.4 158.7 416.1 143.0 166.7 66.6 422.8 154.3 174.4 224.5 135.1 191.4 158.8 458.8 244.4 317.6 259.4 207.3 307.5 294.9 175.4 264.1 393.5 399.2 340.7 853.3 231.1 135.6 327.4 402.0 385.5 215.3 282.2 391.6 265.9 164.5 198.8 463.2 286.8 679.1 345.7 217.5 249.6 251.4 250.4 320.2 245.7 306.2 282.2 255.8 195.1 249.0 415.5 313.4 314.7 427.4 148.6 284.7 345.2 158.6 359.6 220.2 618.7 160.8 264.2 273.9 382.9 631.9 359.4 249.2 362.5 240.7 251.9 500.8 122.4 351.2 295.8 208.8 310.3 157.3 430.1 186.7 225.0 225.4 112.5 221.2 88.0 123.1 88.8 144.2 145.6 117.2 128.8 127.3 101.4 102.1 111.4 132.4 144.3 161.2 238.7 135.0 430.4 440.2 416.5 552.8 448.5 454.1 444.7 443.3 436.7 416.1 422.8 458.8 188.4 169.9 106.5 26.1 107.9 146.8 176.8 215.9 100.2 105.4 136.0 200.3 125.5 170.1 157.4 292.4 58.4 297.8 112.9 283.9 481.3 264.4 34.0 266.4 139.5 170.9 226.7 98.2 34.7 223.4 211.4 149.1 85.1 208.5 159.0 149.8 162.4 104.1 287.9 80.8 30.0 284.6 256.3 127.8 131.5 51.0 234.9 139.1 193.9 19.7 236.2 435.8 148.3 20.1 61.4 317.5 379.3 240.3 117.0 240.4 388.9 781.8 253.1 127.6 203.8 101.8 210.8 65.6 77.2 106.3 150.0 342.3 124.9 90.9 160.5 184.3 DYNLT2B "MGC33212, TCTEX1D2" ENSG00000213123 "Dynein light chain Tctex-type 2B" Q8WW35 3 196291219-196318299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Cardiomyocytes: 6.2;Cytotrophoblasts: 29.4;Extravillous trophoblasts: 9.9;Hofbauer cells: 16.8;Syncytiotrophoblasts: 6.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 21.9;dendritic cells: 16.2;T-cells: 25.1" "Cell line enhanced" "Detected in many" "T-47d: 101.7" HPA049555 Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA049555: AB_2680816" "unprognostic (1.16e-1)" "prognostic favorable (7.83e-4)" "unprognostic (5.34e-2)" "unprognostic (1.59e-2)" "unprognostic (1.47e-1)" "unprognostic (5.63e-2)" "unprognostic (2.65e-2)" "unprognostic (4.61e-1)" "unprognostic (9.98e-3)" "unprognostic (3.99e-2)" "unprognostic (3.44e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (6.23e-4)" "unprognostic (3.73e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (2.32e-1)" 5.0 7.9 15.2 4.5 15.7 5.1 6.5 14.6 18.6 8.7 15.0 9.1 3.4 7.1 7.9 13.0 36.2 5.1 6.3 15.2 16.0 16.9 2.3 7.0 8.8 15.2 16.8 7.3 5.1 7.9 13.8 3.1 17.0 7.0 4.2 15.0 5.2 3.9 3.0 8.4 4.0 3.7 15.7 4.3 5.0 30.9 16.6 14.7 10.1 1.5 6.0 6.7 9.4 15.0 33.1 23.9 45.3 28.0 11.1 22.3 5.4 13.8 9.3 16.8 18.8 7.9 45.0 21.0 23.0 12.1 7.0 33.7 17.8 14.5 16.3 18.4 13.3 8.6 22.3 3.4 12.7 6.4 0.9 12.1 38.2 14.7 17.1 30.5 10.2 44.0 13.3 10.8 32.6 79.0 28.9 29.4 29.6 36.6 41.5 37.3 7.7 8.7 38.9 13.4 50.9 39.7 29.2 17.2 28.0 18.7 101.7 18.3 19.2 15.0 5.8 6.1 18.0 16.9 38.0 48.8 45.0 11.4 25.8 0.0 3.1 1.4 11.7 1.2 7.1 21.9 13.9 9.0 8.8 13.7 9.1 9.4 1.8 4.6 0.8 16.2 25.1 6.3 15.2 15.7 14.6 18.6 15.2 16.0 15.2 16.8 17.0 15.7 16.6 15.0 5.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 29.4 2.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 9.9 3.3 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 6.2 0.5 0.0 0.0 0.0 DYNLT3 "TCTE1L, TCTEX1L" ENSG00000165169 "Dynein light chain Tctex-type 3" P51808 X 37836757-37847571 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 738.3;Glandular and luminal cells: 265.2;Late spermatids: 445.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003938 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "HPA003938: AB_1847920" "unprognostic (1.27e-1)" "unprognostic (5.14e-2)" "unprognostic (1.00e-1)" "unprognostic (7.62e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (1.13e-1)" "unprognostic (5.15e-3)" "unprognostic (6.91e-2)" "unprognostic (2.72e-1)" "unprognostic (2.37e-1)" "unprognostic (3.59e-2)" "unprognostic (1.88e-1)" "unprognostic (3.65e-3)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" "unprognostic (2.72e-1)" "unprognostic (2.69e-2)" 29.0 60.8 25.9 17.7 27.7 27.1 24.4 26.4 35.1 33.3 22.4 23.7 12.1 32.7 25.4 63.6 18.7 37.4 32.0 30.4 39.1 50.3 44.9 24.7 14.7 35.0 33.4 23.0 13.9 40.3 23.4 26.4 38.1 27.2 22.2 33.1 19.2 27.7 12.6 11.4 14.9 37.2 26.5 18.4 23.5 16.9 30.1 14.8 26.5 18.2 21.9 32.8 30.7 26.6 48.2 13.9 1.4 0.1 58.1 67.0 7.5 32.0 35.0 17.7 29.2 25.8 25.2 16.9 15.5 65.5 51.2 18.9 20.1 27.5 34.8 28.7 23.4 13.4 66.0 13.6 29.1 0.0 9.5 29.3 38.4 43.2 19.1 53.0 55.3 0.0 6.9 23.9 82.5 15.7 0.4 20.8 8.1 24.7 69.2 24.0 0.1 27.9 32.4 34.7 30.8 13.1 58.9 12.0 97.7 2.8 14.7 14.3 29.8 36.7 19.9 43.0 36.7 15.9 15.4 19.7 88.8 22.0 46.4 20.6 9.5 7.3 17.2 14.0 35.9 17.5 24.0 22.9 6.3 12.3 20.5 20.2 7.6 16.5 8.7 7.3 14.7 14.7 25.9 27.7 26.4 35.1 30.4 39.1 35.0 33.4 38.1 26.5 30.1 26.6 62.0 38.5 28.9 6.2 37.8 15.4 121.8 48.7 10.8 28.2 38.9 20.8 31.8 25.8 46.8 64.4 2.1 12.5 31.9 26.0 133.1 53.8 738.3 80.4 75.6 47.4 55.7 8.6 22.9 46.9 29.1 64.7 42.8 265.2 87.6 15.4 42.8 34.0 38.2 70.7 24.8 18.4 85.5 31.5 80.0 445.7 44.1 42.5 42.7 12.2 49.0 57.2 28.8 7.1 7.6 102.1 28.0 103.4 22.9 116.7 20.2 143.6 53.0 50.8 39.5 53.2 81.6 13.1 5.8 74.7 22.7 45.4 68.0 27.4 17.7 118.8 DZIP1 "DZIP, KIAA0996" ENSG00000134874 "DAZ interacting zinc finger protein 1" Q86YF9 13 95578202-95644706 "Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 384.1;Late spermatids: 774.5;Spermatocytes: 222.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054891, HPA057272" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 43: Testis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" "HPA054891: AB_2682631, HPA057272: AB_2683390" "unprognostic (6.74e-3)" "unprognostic (7.65e-2)" "unprognostic (1.94e-1)" "unprognostic (4.64e-3)" "unprognostic (4.82e-2)" "unprognostic (5.52e-3)" "unprognostic (6.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.34e-2)" "unprognostic (8.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.41e-3)" "unprognostic (1.48e-1)" "unprognostic (3.64e-2)" "unprognostic (3.89e-3)" 5.0 3.4 8.6 2.5 8.5 0.1 4.4 6.9 9.4 12.4 5.7 10.7 1.0 12.6 7.2 3.2 12.4 5.1 4.3 7.7 8.7 11.4 1.1 4.6 2.2 7.0 8.1 16.3 9.9 0.4 10.3 2.5 6.1 6.4 1.8 4.0 2.3 6.2 1.3 1.6 4.0 6.1 5.6 1.5 4.7 14.8 11.5 0.8 2.4 2.1 1.7 7.9 7.1 7.1 1.1 4.2 17.5 15.5 14.5 16.2 3.6 11.0 13.2 12.7 15.2 0.2 0.0 0.0 2.5 9.4 5.5 0.0 11.7 3.8 14.8 1.1 9.6 15.6 4.4 11.0 9.2 0.1 0.0 11.7 0.4 4.2 5.8 23.1 9.1 1.1 0.0 0.1 11.4 0.0 0.0 0.0 8.6 0.0 0.4 0.0 10.1 0.0 15.4 1.8 4.2 9.9 8.3 0.0 0.6 22.4 0.0 7.3 1.3 12.3 5.3 1.8 8.8 0.0 0.0 0.0 3.5 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 8.5 6.9 9.4 7.7 8.7 7.0 8.1 6.1 5.6 11.5 7.1 2.4 0.0 0.0 63.6 0.0 0.6 1.1 3.1 4.6 18.7 0.6 3.4 3.5 2.8 3.9 1.8 4.2 4.5 0.0 0.0 7.9 20.8 384.1 37.2 34.1 2.5 0.0 0.0 86.8 0.2 2.6 19.0 0.5 2.7 0.0 3.1 2.9 0.4 0.7 6.7 95.7 0.0 4.1 0.3 1.5 774.5 38.8 1.2 3.6 19.7 2.0 8.3 0.0 106.6 5.1 0.6 0.0 43.6 0.0 0.8 0.0 24.4 19.4 1.5 19.7 18.2 15.8 222.8 12.6 1.2 1.0 1.8 0.5 20.8 0.0 0.3 E2F1 "RBBP3, RBP3" ENSG00000101412 "E2F transcription factor 1" Q01094 20 33675477-33686385 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.0;Granulosa cells: 11.4;Spermatogonia: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000329, HPA008003, CAB019308, HPA029735" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 22: NK-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Centrosome" "CAB000329: AB_627476, CAB019308: , HPA008003: AB_1847936, HPA029735: AB_2673176" "unprognostic (7.46e-2)" "prognostic favorable (9.22e-6)" "unprognostic (2.11e-2)" "prognostic unfavorable (4.33e-5)" "unprognostic (1.51e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.83e-5)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (9.66e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.15e-2)" "prognostic unfavorable (8.99e-5)" "unprognostic (1.05e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.62e-4)" "unprognostic (1.91e-1)" 1.8 5.5 7.1 5.6 7.1 34.3 1.6 5.2 9.2 1.8 3.9 3.8 3.2 1.2 0.2 5.7 1.3 0.7 1.4 6.1 5.6 0.9 1.8 3.7 8.7 7.6 6.4 3.5 1.0 1.3 0.6 2.4 6.5 1.9 3.9 0.7 1.9 0.9 1.6 4.7 4.1 2.8 7.0 5.0 3.7 10.4 6.9 10.7 0.8 0.8 6.9 2.4 2.5 8.3 48.1 45.4 52.0 40.5 5.2 3.6 39.3 45.0 21.4 55.9 46.7 81.1 48.0 87.3 44.2 20.2 67.7 35.4 25.3 23.8 24.8 26.4 36.5 71.6 71.9 47.7 0.4 34.0 43.6 2.8 1.4 30.6 5.4 5.7 14.6 54.4 19.3 60.0 34.9 42.3 72.8 71.6 15.6 47.9 64.6 71.4 140.7 36.2 9.6 28.7 76.7 54.1 54.6 37.6 22.7 14.8 47.3 42.4 7.9 65.0 37.7 45.8 64.8 58.1 42.0 72.6 54.1 20.0 39.3 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.1 0.1 0.1 7.1 7.1 5.2 9.2 6.1 5.6 7.6 6.4 6.5 7.0 6.9 8.3 1.1 0.0 1.1 0.7 3.6 2.9 1.7 0.5 0.0 2.3 3.1 4.3 0.4 0.0 1.4 0.0 0.0 5.0 2.9 2.4 0.0 0.9 1.0 0.3 1.0 1.6 0.0 25.0 1.5 0.2 9.6 3.0 7.7 1.2 0.0 11.4 0.7 0.8 4.4 0.0 0.5 4.6 2.0 0.6 2.1 3.1 2.1 3.1 1.8 1.0 0.1 1.5 1.0 1.0 3.4 0.6 0.5 1.2 9.7 0.5 1.4 0.1 0.2 2.3 0.0 1.0 3.0 7.5 32.9 3.7 1.7 1.8 3.3 1.2 7.0 3.5 E2F3 ENSG00000112242 "E2F transcription factor 3" O00716 6 20401879-20493714 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029779, HPA065012" Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nuclear speckles" Cytosol "HPA029779: AB_2732448, HPA065012: AB_2685403" "unprognostic (4.10e-2)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.80e-3)" "unprognostic (2.96e-1)" "unprognostic (9.14e-2)" "unprognostic (8.99e-3)" "unprognostic (9.13e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.69e-4)" "unprognostic (1.14e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (1.63e-8)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (3.50e-1)" "unprognostic (5.99e-3)" 6.5 4.9 4.8 9.8 5.2 19.8 4.1 2.8 5.7 3.3 3.0 5.4 5.2 3.6 3.9 4.9 2.5 6.4 5.1 6.4 4.6 5.8 4.4 4.9 11.0 3.7 4.6 1.4 2.1 3.1 1.8 5.6 4.2 3.3 6.3 6.1 2.7 3.1 10.0 2.6 5.7 6.0 3.7 8.4 3.6 3.4 5.5 8.6 8.5 9.3 9.5 8.5 2.7 3.8 14.3 11.6 32.2 35.1 10.9 11.9 22.0 18.9 16.8 18.2 19.9 14.3 8.8 32.3 35.2 18.2 16.9 14.6 37.8 17.4 30.3 12.2 25.3 58.1 20.4 16.3 11.6 38.6 33.0 9.7 12.6 17.7 21.6 18.8 12.7 29.8 65.3 19.4 20.9 15.0 43.6 43.2 24.2 11.0 11.9 46.5 27.8 36.5 21.8 25.1 22.9 42.2 17.3 24.1 26.3 20.0 12.4 23.4 17.2 28.6 17.4 14.2 30.5 12.1 40.1 38.3 7.1 23.2 41.3 5.6 2.3 1.1 1.6 1.6 2.0 0.4 1.0 2.4 2.6 0.4 0.8 1.8 7.2 3.5 1.1 1.1 1.6 1.1 4.8 5.2 2.8 5.7 6.4 4.6 3.7 4.6 4.2 3.7 5.5 3.8 4.8 0.0 2.6 53.8 10.6 9.2 12.3 7.0 7.4 34.1 11.9 7.2 10.6 4.3 10.6 7.3 22.9 8.3 15.0 12.0 9.8 7.6 12.2 3.9 14.1 8.5 12.0 17.2 67.7 6.9 13.8 9.2 12.8 10.6 20.3 32.3 14.6 4.7 17.1 32.0 31.9 11.7 4.1 47.2 17.7 5.7 2.8 28.7 5.4 27.2 23.8 2.9 15.5 37.7 2.9 14.8 10.3 3.0 19.1 22.1 4.5 25.1 2.2 9.0 0.0 9.0 11.5 3.0 4.7 16.5 8.9 3.1 15.3 5.7 13.8 18.4 EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 485.6;monocytes: 505.7;Syncytiotrophoblasts: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cell line enriched" "Detected in some" 13 "HDLM-2: 218.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" 4.7 4.7 3.8 14.6 3.3 1.2 1.7 3.4 5.3 1.5 3.2 3.0 4.3 1.1 0.1 1.0 2.4 5.4 1.4 3.8 3.7 2.1 3.3 2.9 20.2 5.7 4.2 1.3 2.5 0.4 1.7 147.6 5.2 1.8 1.6 0.1 1.8 1.4 0.2 0.6 8.4 2.1 4.5 34.0 3.7 0.9 5.8 9.4 0.9 0.4 7.3 4.8 1.0 6.1 0.1 1.7 0.1 0.0 0.0 0.0 7.3 0.7 4.2 0.4 0.2 1.3 1.2 4.2 16.4 0.0 2.0 0.1 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.2 0.3 0.0 7.7 0.4 0.0 2.1 0.6 1.6 0.1 0.0 0.4 0.5 0.1 0.1 0.0 3.0 0.4 0.0 0.0 0.0 0.6 0.3 2.6 0.0 0.2 0.4 0.0 0.0 0.0 2.7 0.2 0.2 0.9 0.3 5.1 0.0 0.2 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.1 0.0 0.0 4.8 0.0 18.7 0.0 0.0 0.8 14.7 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.6 3.8 3.3 3.4 5.3 3.8 3.7 5.7 4.2 5.2 4.5 5.8 6.1 0.5 0.0 0.5 0.3 8.4 0.4 0.0 13.3 0.0 0.0 0.2 0.6 0.1 1.5 10.7 0.0 0.0 10.6 0.5 0.0 0.0 2.8 0.0 0.3 0.4 1.3 0.0 0.0 0.6 0.9 485.6 0.7 0.0 0.3 11.4 0.0 1.1 0.1 9.6 0.0 0.4 0.0 6.1 102.6 11.3 0.0 0.0 19.0 0.0 5.6 505.7 0.1 0.0 0.0 0.1 0.6 0.0 0.0 2.6 0.1 0.0 0.6 1.5 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 336.4 1.0 0.1 0.0 0.1 ECHDC1 dJ351K20.2 ENSG00000093144 "Ethylmalonyl-CoA decarboxylase 1" Q9NTX5 6 127288712-127343609 "Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 230.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035445, HPA035446" Uncertain Approved Vesicles NA NA 56000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA035445: AB_10669860, HPA035446: AB_2732468" "unprognostic (9.57e-2)" "unprognostic (1.63e-2)" "unprognostic (2.46e-3)" "unprognostic (1.34e-1)" "unprognostic (4.09e-1)" "unprognostic (3.68e-2)" "unprognostic (5.03e-3)" "unprognostic (4.89e-3)" "unprognostic (4.97e-2)" "unprognostic (1.76e-1)" "unprognostic (3.99e-1)" "unprognostic (9.97e-2)" "unprognostic (8.21e-3)" "unprognostic (6.83e-2)" "unprognostic (2.86e-1)" "unprognostic (1.39e-1)" "unprognostic (1.40e-2)" 92.9 29.4 21.8 36.8 24.5 16.2 37.3 26.4 28.6 36.4 32.3 58.4 46.8 21.4 23.0 33.5 23.2 27.5 42.6 22.0 27.0 92.5 93.8 56.8 41.3 28.1 24.7 21.1 27.9 26.2 14.1 36.2 28.5 33.8 53.8 30.0 46.3 28.4 39.3 22.7 40.7 33.4 24.4 28.4 37.0 18.2 24.7 41.1 38.7 52.2 42.6 43.4 23.4 32.3 58.3 45.6 64.0 59.3 92.9 87.7 54.1 92.7 112.1 78.0 99.0 79.7 43.1 87.6 77.8 88.6 88.4 46.9 0.1 69.6 98.3 52.4 43.3 116.9 58.4 128.3 82.6 158.0 63.4 99.6 81.9 73.1 61.6 70.6 71.8 63.2 147.6 51.6 105.7 55.1 105.7 73.5 52.9 29.0 55.8 49.0 78.7 72.3 142.8 70.8 73.3 71.2 52.1 1.8 131.3 48.3 1.8 182.6 75.2 47.8 76.9 121.8 104.8 65.7 141.0 116.3 87.2 136.4 114.7 19.0 71.6 24.0 23.4 57.5 24.7 28.6 19.8 22.9 66.6 29.2 23.7 24.2 28.6 15.3 43.1 50.5 22.1 43.9 21.8 24.5 26.4 28.6 22.0 27.0 28.1 24.7 28.5 24.4 24.7 32.3 37.0 96.1 114.0 32.3 59.7 26.1 42.3 94.2 35.3 26.4 30.8 28.3 60.8 32.9 102.4 31.3 31.3 106.8 49.3 35.6 127.2 76.1 64.7 47.0 48.3 32.6 13.8 22.9 47.4 79.5 85.6 45.8 38.2 40.2 43.7 32.9 26.0 68.8 85.8 28.6 41.0 35.7 59.0 48.4 38.7 24.4 32.9 55.9 35.6 40.3 55.3 33.5 47.4 55.3 95.0 54.4 41.1 31.2 48.3 31.1 74.4 230.3 47.0 42.3 26.3 55.7 33.0 27.6 28.6 34.7 22.9 65.5 46.3 88.2 56.9 52.7 ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 113.3;Fibroblasts: 118.6;Melanocytes: 74.7;Pancreatic endocrine cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 402.1;BJ hTERT+: 293.1;fHDF/TERT166: 279.6;hTEC/SVTERT24-B: 195.6;LHCN-M2: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" 49.3 15.4 7.6 11.8 8.5 0.8 27.1 7.3 14.7 293.8 6.1 17.7 9.4 51.2 484.1 1370.5 20.1 76.5 81.3 8.1 8.3 15.9 61.2 26.3 1.2 17.4 8.9 8.9 4.1 3.5 12.7 44.6 15.4 15.5 18.1 0.9 223.9 14.0 7.0 70.0 12.4 32.6 8.9 11.5 12.4 2.7 9.4 1.3 11.1 7.8 135.0 24.4 360.1 10.7 35.4 3.5 12.6 0.2 73.9 402.1 11.4 126.9 293.1 76.2 99.5 1.9 19.1 0.6 1.3 279.6 8.8 71.5 0.2 15.0 79.3 0.6 0.7 5.7 4.1 0.7 20.4 0.3 125.5 35.7 0.9 195.6 7.2 112.8 21.3 0.7 27.7 0.8 215.2 0.1 0.4 4.2 1.4 147.8 4.1 2.0 92.7 0.5 2.8 0.1 0.8 0.4 28.8 0.9 106.4 5.8 0.3 34.0 5.8 159.3 23.9 18.3 27.9 0.5 1.1 1.5 84.6 11.7 22.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.6 8.5 7.3 14.7 8.1 8.3 17.4 8.9 15.4 8.9 9.4 10.7 9.1 0.0 1.1 2.9 0.6 14.7 1.9 6.9 0.0 0.7 0.5 0.6 1.8 7.2 7.9 3.7 0.0 2.2 0.6 1.0 0.0 6.2 0.3 3.1 113.3 15.7 0.0 0.0 12.1 4.3 40.9 118.6 7.7 2.5 10.2 1.0 42.5 1.0 17.0 1.7 10.9 1.4 18.3 2.2 22.8 0.3 9.9 10.8 74.7 2.8 0.1 0.5 0.0 1.0 4.4 70.2 1.1 22.2 0.4 1.5 0.1 0.1 0.4 1.2 13.1 4.1 32.3 0.7 0.6 28.1 19.0 10.9 2.1 5.0 0.5 6.9 ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 73.3;Hepatocytes: 49.3;Leydig cells: 122.1;Peritubular cells: 69.6;Skeletal myocytes: 43.6;Smooth muscle cells: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 19.1;ASC TERT1: 34.5;HSkMC: 36.8;hTCEpi: 42.8;hTERT-HME1: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Approved "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" 122.1 14.3 5.0 2.1 5.0 0.6 34.8 6.0 4.9 43.5 8.1 6.8 9.0 40.8 23.2 9.0 30.0 31.7 31.5 4.5 11.6 28.4 81.5 22.5 8.3 5.2 10.3 91.6 6.3 9.1 6.1 3.5 5.8 21.2 7.4 0.3 7.2 22.2 7.4 9.7 14.8 27.8 4.4 0.9 4.3 16.8 8.0 5.0 11.4 24.6 7.8 13.3 11.1 12.0 0.7 0.1 0.4 0.0 19.1 34.5 1.3 0.8 1.1 0.1 0.5 0.6 0.0 0.0 0.1 1.9 0.3 0.5 0.9 0.8 0.1 4.4 0.0 0.0 0.0 0.0 3.3 0.2 0.0 36.8 42.8 0.9 11.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.1 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 5.0 6.0 4.9 4.5 11.6 5.2 10.3 5.8 4.4 8.0 12.0 12.9 0.0 2.3 5.5 0.3 11.5 0.1 0.6 0.6 3.0 0.3 1.3 5.5 1.5 2.0 0.0 2.1 0.1 0.3 0.2 0.0 0.1 5.1 0.6 18.6 5.2 0.0 0.8 3.4 0.0 16.2 73.3 0.5 0.5 0.0 18.2 2.2 49.3 0.4 0.0 2.8 0.4 0.0 1.3 15.4 8.9 122.1 1.1 5.4 17.8 0.1 0.1 0.0 0.5 2.9 0.0 0.2 69.6 1.4 0.1 11.1 9.2 3.3 2.5 26.3 43.6 50.2 0.9 0.6 0.9 9.1 0.8 0.9 13.5 0.6 0.2 ECRG4 "augurin, C2orf40" ENSG00000119147 "ECRG4 augurin precursor" Q9H1Z8 2 106063246-106078155 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 225.3" "Cell type enhanced" "Detected in some" "Adipocytes: 87.6;Fibroblasts: 25.3;Smooth muscle cells: 19.1" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 72.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 8.5;naive CD8 T-cell: 7.2" "Lineage enriched" "Detected in single" 83 "T-cells: 8.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008546 Uncertain "Secreted to blood" NA NA 330000 "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: Fibroblasts - ECM organization" "HPA008546: AB_2066524" "prognostic favorable (4.58e-4)" "unprognostic (3.91e-1)" "unprognostic (2.44e-2)" "unprognostic (1.34e-2)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.61e-3)" "unprognostic (6.56e-3)" "unprognostic (1.82e-2)" "unprognostic (1.25e-1)" "unprognostic (2.35e-3)" "unprognostic (1.36e-2)" "unprognostic (1.06e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (9.11e-3)" "unprognostic (1.30e-4)" 66.7 27.6 5.3 1.1 6.0 0.0 49.6 9.6 5.3 73.8 225.3 47.6 5.3 24.6 28.4 20.2 47.5 9.4 25.7 12.0 13.0 47.1 3.2 27.6 1.7 14.9 21.5 13.2 5.9 0.7 96.2 8.5 15.4 55.1 5.6 0.1 20.4 101.8 10.3 14.1 19.2 9.0 19.4 25.8 165.8 27.0 12.2 2.8 101.1 6.9 0.3 79.6 58.2 11.7 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 2.0 1.3 0.0 0.0 8.5 7.2 0.0 0.0 0.0 0.0 0.8 1.4 5.3 6.0 9.6 5.3 12.0 13.0 14.9 21.5 15.4 19.4 12.2 11.7 87.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 ECSIT SITPEC ENSG00000130159 "ECSIT signaling integrator" Q9BQ95 19 11505929-11529172 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042979 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA042979: AB_10964063" "unprognostic (9.88e-2)" "unprognostic (3.57e-3)" "unprognostic (2.93e-1)" "unprognostic (3.55e-3)" "unprognostic (2.27e-2)" "unprognostic (3.35e-2)" "unprognostic (2.18e-1)" "unprognostic (1.24e-1)" "unprognostic (2.92e-1)" "unprognostic (2.18e-1)" "unprognostic (1.01e-2)" "unprognostic (4.08e-2)" "prognostic favorable (1.48e-9)" "unprognostic (2.30e-3)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (5.95e-2)" 26.2 38.0 28.5 14.9 28.4 24.7 26.8 32.4 38.5 32.2 29.6 42.2 39.5 29.7 9.4 29.2 28.5 15.0 128.5 28.7 29.3 36.6 51.6 20.8 18.0 30.5 28.2 43.1 56.3 30.6 24.3 9.8 31.6 29.8 18.9 12.9 45.7 16.0 124.7 29.6 28.3 16.5 26.1 21.8 48.9 15.0 30.8 15.6 26.2 130.4 13.3 34.3 27.5 30.0 40.0 35.8 20.4 29.2 30.0 33.6 23.1 21.1 26.4 41.8 33.4 52.6 26.4 58.7 42.0 25.4 38.0 52.1 51.6 42.6 14.6 33.2 42.7 54.5 21.6 48.1 29.7 31.5 42.8 35.9 46.0 35.0 38.1 22.1 31.8 53.7 59.2 56.2 15.6 55.2 53.7 48.6 54.6 51.8 91.4 53.3 22.0 77.1 22.3 24.2 77.3 50.2 24.6 38.7 42.4 9.6 45.9 46.3 16.2 44.4 31.2 64.4 38.5 52.7 106.5 28.7 37.0 46.9 32.2 4.1 32.5 12.0 26.6 41.1 30.8 41.7 28.8 25.1 42.3 39.2 31.9 29.3 6.1 26.1 38.3 23.5 35.4 29.7 28.5 28.4 32.4 38.5 28.7 29.3 30.5 28.2 31.6 26.1 30.8 30.0 19.7 9.6 15.7 13.1 25.2 44.5 61.6 48.3 40.9 23.2 38.7 44.2 74.7 52.9 28.3 20.2 12.5 34.5 18.0 44.3 82.2 42.1 18.0 10.2 16.3 23.4 37.3 31.1 15.3 78.5 45.7 27.5 29.6 9.5 22.9 47.1 27.5 49.4 31.1 18.5 19.4 49.3 16.2 29.6 23.5 52.2 34.5 19.5 28.4 3.7 22.2 30.4 29.9 8.0 9.9 38.4 34.8 32.0 21.0 55.9 70.0 101.5 18.5 30.6 32.9 32.7 36.4 17.6 45.1 37.6 41.9 25.2 20.3 53.7 84.6 56.3 EDDM13 ENSG00000267710 "Epididymal protein 13" A0A1B0GTR0 19 56272748-56310454 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 63 "epididymis: 98.8" "Cell type enhanced" "Detected in some" "Adipocytes: 1.5;Alveolar cells type 2: 1.3;Breast myoepithelial cells: 2.2;dendritic cells: 1.1;Endothelial cells: 2.2;granulocytes: 1.3;Respiratory ciliated cells: 1.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.08e-4)" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (1.40e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.34e-1)" "unprognostic (2.29e-1)" "unprognostic (3.22e-3)" "unprognostic (1.33e-1)" "unprognostic (5.23e-3)" "unprognostic (2.93e-2)" "unprognostic (9.16e-2)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (3.84e-2)" "unprognostic (4.20e-1)" 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 98.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.5 0.1 0.1 0.1 0.2 0.0 0.1 0.1 1.5 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.7 0.6 2.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.4 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 EDDM3A "FAM12A, HE3-ALPHA" ENSG00000181562 "Epididymal protein 3A" Q14507 14 20745887-20748380 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "epididymis: 636.1" "Cell type enriched" "Detected in some" 26 "Collecting duct cells: 29.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049952 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA049952: AB_2680970" "unprognostic (1.42e-1)" "unprognostic (9.88e-2)" "unprognostic (8.56e-3)" "unprognostic (2.10e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 636.1 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 35.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 29.5 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 EDDM3B "FAM12B, HE3-BETA" ENSG00000181552 "Epididymal protein 3B" P56851 14 20768404-20770948 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 279 "epididymis: 2563.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.3;NB-4: 2.6" "Not detected" "Not detected" HPA001323 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "HPA001323: AB_1848377" "unprognostic (2.40e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2563.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EDEM2 "bA4204.1, C20orf31, C20orf49, FLJ10783" ENSG00000088298 "ER degradation enhancing alpha-mannosidase like protein 2" Q9BV94 20 35115364-35147336 "Predicted intracellular proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 137.9;Plasma cells: 89.0;Syncytiotrophoblasts: 94.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037238, HPA048353" Approved "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB037238: AB_1840826, HPA048353: AB_2680369" "unprognostic (1.19e-1)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.05e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.31e-3)" "unprognostic (1.81e-1)" "unprognostic (2.10e-2)" "unprognostic (9.87e-2)" "unprognostic (1.46e-1)" "unprognostic (5.09e-2)" "prognostic unfavorable (4.76e-6)" "unprognostic (4.53e-2)" "unprognostic (1.31e-1)" "unprognostic (3.50e-3)" "unprognostic (2.29e-2)" 21.1 26.9 10.3 16.2 11.4 27.7 17.9 16.0 12.8 18.5 13.6 19.5 20.0 11.6 44.9 14.5 16.2 14.7 15.0 9.8 10.7 19.1 38.9 26.7 20.1 13.4 11.4 10.4 32.4 13.2 24.5 28.1 12.9 16.0 21.8 10.7 19.1 15.5 7.5 13.9 19.4 15.4 11.0 32.5 16.4 6.6 14.8 16.8 15.3 5.9 21.7 16.4 12.2 12.5 18.6 54.4 8.6 34.0 98.0 33.9 49.2 20.8 70.5 24.4 34.4 61.3 47.7 16.0 61.3 40.9 77.0 37.6 31.5 43.3 19.6 12.3 8.8 31.6 11.8 58.7 54.1 23.2 117.6 41.3 59.4 23.5 58.2 60.2 91.9 30.3 14.9 66.5 33.9 20.6 18.6 28.9 9.7 52.8 35.0 15.5 29.5 33.6 54.6 16.0 7.1 11.1 21.8 55.8 53.9 36.3 26.2 38.5 41.0 36.9 22.0 21.9 25.6 34.5 23.2 9.7 64.7 29.2 31.4 35.9 96.9 75.3 39.9 72.4 78.4 42.3 36.4 39.6 101.4 42.0 26.0 32.9 67.2 42.9 72.9 59.1 47.7 79.9 10.3 11.4 16.0 12.8 9.8 10.7 13.4 11.4 12.9 11.0 14.8 12.5 16.7 16.0 17.4 6.8 27.5 4.0 14.6 34.7 6.2 3.7 12.0 9.3 4.6 24.3 18.9 12.9 2.1 72.9 27.4 14.7 11.7 35.5 2.5 11.4 13.8 16.4 4.8 13.3 5.2 29.1 137.9 14.1 7.7 16.6 55.1 13.6 13.9 23.3 72.2 0.0 6.5 13.8 32.6 21.3 7.9 1.2 7.8 28.3 12.4 9.4 26.8 7.9 14.4 1.5 6.9 28.9 16.1 5.3 89.0 12.8 43.6 18.9 15.3 6.5 13.1 7.9 19.0 8.7 11.2 8.9 4.7 94.7 18.7 15.7 17.3 12.7 EDEM3 C1orf22 ENSG00000116406 "ER degradation enhancing alpha-mannosidase like protein 3" Q9BZQ6 1 184690237-184754907 "Enzymes, Predicted intracellular proteins" "Unfolded protein response" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025754, HPA025755, HPA027297" Approved Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum" "HPA025754: AB_1845638, HPA025755: AB_1845639, HPA027297: AB_2672205" "unprognostic (1.74e-1)" "unprognostic (1.64e-2)" "unprognostic (3.08e-2)" "unprognostic (2.67e-2)" "unprognostic (2.30e-1)" "unprognostic (3.10e-2)" "unprognostic (7.52e-3)" "unprognostic (1.82e-1)" "unprognostic (7.06e-2)" "unprognostic (1.66e-1)" "unprognostic (1.66e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.63e-6)" "unprognostic (4.72e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-2)" "unprognostic (2.01e-1)" 14.3 12.4 3.8 13.8 4.8 8.2 10.9 6.6 5.1 13.7 4.3 20.6 18.8 8.8 8.0 9.2 6.6 11.7 7.2 4.1 6.5 10.6 20.3 11.2 10.2 4.7 5.7 5.7 15.7 13.0 7.1 20.8 4.6 13.5 24.0 11.4 13.2 8.7 12.2 6.6 16.3 12.0 4.5 10.5 35.8 7.4 5.5 10.8 11.8 11.4 10.7 13.6 5.8 6.3 15.1 11.2 15.0 13.4 53.8 55.0 24.5 29.9 20.7 11.1 11.6 5.9 42.4 10.5 31.8 22.8 11.3 20.1 14.6 15.6 16.4 10.3 11.9 13.8 11.7 8.5 20.7 36.4 19.5 31.6 18.8 27.1 24.2 21.0 30.4 27.4 36.8 47.4 21.6 12.5 29.3 18.8 21.2 34.1 10.2 12.7 11.6 36.2 16.1 10.4 16.9 23.9 14.7 25.2 20.8 24.9 23.7 56.3 36.1 16.1 7.2 34.3 25.5 72.1 29.8 13.6 21.3 40.7 35.6 5.0 3.5 2.2 1.4 3.5 2.5 1.3 2.2 1.7 3.1 0.9 3.0 1.6 3.6 2.2 3.6 1.6 1.5 1.8 3.8 4.8 6.6 5.1 4.1 6.5 4.7 5.7 4.6 4.5 5.5 6.3 35.1 19.2 19.3 41.4 19.9 16.7 8.4 9.8 19.9 26.1 20.4 11.4 16.0 12.8 21.8 14.7 25.0 13.8 13.2 55.1 0.0 14.0 16.0 14.3 21.2 25.9 30.6 32.4 58.2 35.6 10.9 28.0 96.8 17.0 21.0 12.9 19.2 47.0 13.0 21.9 62.8 76.5 2.0 40.1 30.3 7.1 20.5 33.0 19.6 36.5 31.0 7.8 11.3 47.3 61.6 20.0 28.1 18.0 73.6 27.1 21.4 9.7 28.1 15.2 19.7 20.3 18.7 15.0 8.7 18.2 20.5 19.4 24.9 53.8 32.4 19.1 EDIL3 DEL1 ENSG00000164176 "EGF like repeats and discoidin domains 3" O43854 5 83940554-84384880 "Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 256.8" "Group enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 561.4;Oligodendrocytes: 2119.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 547.0;LHCN-M2: 169.8;TIME: 203.3;U-2 OS: 163.2;U-87 MG: 112.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020415 Approved "Secreted to blood" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA020415: AB_2670434" "unprognostic (9.93e-3)" "unprognostic (2.38e-1)" "unprognostic (2.71e-2)" "unprognostic (8.63e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (9.19e-2)" "unprognostic (6.64e-3)" "unprognostic (2.98e-1)" "unprognostic (1.56e-1)" "unprognostic (1.04e-1)" "unprognostic (1.03e-3)" "unprognostic (2.52e-2)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (1.28e-3)" 13.9 21.7 55.3 13.6 126.6 0.2 6.2 93.9 105.1 17.5 7.6 37.0 17.0 26.8 44.9 17.0 10.9 34.0 20.6 68.1 90.1 10.7 0.7 20.9 0.8 118.1 89.3 10.1 3.4 4.2 2.9 4.6 121.0 13.5 38.4 40.2 3.9 22.1 0.8 9.7 26.2 25.8 99.1 3.2 19.7 2.3 82.3 0.3 4.0 0.7 3.6 15.7 9.5 256.8 0.1 1.5 1.4 0.0 3.7 0.2 0.1 4.8 0.0 12.6 16.9 0.0 21.2 0.0 0.1 0.1 8.8 19.6 0.0 0.8 9.3 0.1 9.2 0.0 54.5 0.0 99.9 1.0 0.2 25.6 2.6 61.0 8.5 547.0 21.7 0.0 0.0 0.3 169.8 0.1 0.1 0.3 8.7 0.0 39.4 0.1 41.4 0.1 28.2 0.0 4.5 0.5 0.0 0.3 0.1 26.1 0.2 0.2 203.3 60.8 163.2 2.1 56.6 1.6 0.0 0.1 112.6 0.1 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 126.6 93.9 105.1 68.1 90.1 118.1 89.3 121.0 99.1 82.3 256.8 3.1 9.6 6.0 14.0 0.1 12.1 1.7 13.7 14.8 179.2 0.3 11.7 13.3 0.0 4.5 3.7 2.1 0.3 0.1 5.9 0.0 0.1 32.8 0.4 7.2 10.4 22.9 0.0 219.9 0.0 0.0 34.8 0.0 0.3 5.7 1.3 1.4 0.1 0.3 5.0 216.5 9.2 2.0 0.0 3.3 19.8 2.5 0.3 3.6 32.8 0.0 5.4 0.0 561.4 2119.7 0.4 8.1 3.8 0.0 0.9 0.0 0.9 1.2 11.6 6.6 0.2 40.2 1.9 1.5 9.3 16.1 0.4 0.6 16.2 8.4 0.7 EDN1 ET1 ENSG00000078401 "Endothelin 1" P05305 6 12290361-12297194 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 44.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 749.7;Ductal cells: 316.3;Glandular and luminal cells: 289.7;Pancreatic endocrine cells: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 6 "monocytes: 4.9" "Cell line enhanced" "Detected in many" "EFO-21: 660.4;HUVEC TERT2: 446.8;T-47d: 137.5;TIME: 334.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031976, CAB032500, CAB037291" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted to blood" NA Yes 9740 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Golgi apparatus" Nucleoplasm "CAB032500: AB_2096241, CAB037291: AB_259277, HPA031976: AB_10602489" "unprognostic (1.51e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "unprognostic (9.72e-2)" "unprognostic (3.40e-1)" "unprognostic (1.91e-1)" "unprognostic (6.24e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (8.92e-2)" "unprognostic (4.19e-2)" "unprognostic (3.17e-1)" "unprognostic (8.02e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (3.47e-1)" 44.6 1.8 14.7 7.3 13.8 4.7 23.6 13.6 18.2 6.2 9.7 10.6 10.4 7.0 6.3 12.1 9.4 13.5 7.8 12.6 12.2 7.7 3.1 36.6 5.6 15.1 13.6 2.6 9.6 1.4 1.1 18.5 15.2 5.5 14.5 1.0 12.1 8.9 7.6 11.8 9.8 11.3 13.1 12.3 10.4 4.7 15.7 1.7 3.4 6.4 2.4 9.9 5.9 14.2 10.3 57.6 1.1 0.1 0.3 0.2 0.2 18.2 16.0 15.0 12.4 74.6 8.6 0.0 660.4 7.2 9.2 5.4 0.0 10.6 11.0 0.8 0.0 0.0 2.1 2.3 0.8 0.0 0.0 0.4 6.2 3.0 2.1 4.7 446.8 0.0 0.0 0.0 56.8 1.6 0.2 0.3 0.6 10.4 0.7 0.2 5.1 0.1 35.3 9.4 0.6 0.0 1.8 53.1 0.1 117.2 137.5 0.8 334.3 37.1 30.1 0.7 23.5 0.3 0.4 1.3 0.3 0.0 1.6 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.0 0.0 14.7 13.8 13.6 18.2 12.6 12.2 15.1 13.6 15.2 13.1 15.7 14.2 190.7 173.1 23.8 2.9 0.8 189.9 749.7 99.9 151.4 0.2 68.7 26.8 2.2 8.6 110.6 38.6 0.0 1.8 0.8 189.7 3.9 316.3 13.3 187.2 16.3 236.8 15.6 2.7 3.6 218.9 0.4 9.0 22.4 289.7 1.3 0.8 169.2 1.8 1.8 1.7 3.0 43.8 12.2 5.0 6.7 19.8 5.6 5.3 8.8 6.5 10.9 0.3 0.0 3.5 0.6 268.5 145.7 0.4 0.4 185.8 119.6 8.3 27.4 0.4 6.6 1.8 21.8 1.0 0.6 53.7 64.5 0.8 9.7 0.1 196.6 141.8 EDN2 ET2 ENSG00000127129 "Endothelin 2" P20800 1 41478775-41484683 "Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 26.1;esophagus: 20.8;vagina: 32.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 239.7;Basal respiratory cells: 137.3;Club cells: 146.1;Collecting duct cells: 69.9;Prostatic glandular cells: 62.5;Proximal enterocytes: 91.7" "Cancer enhanced" "Detected in many" "cervical cancer: 24.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;EFO-21: 35.9;HeLa: 13.0;SCLC-21H: 16.8;SK-BR-3: 41.2;U-2 OS: 15.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA028459 Uncertain Approved Cytosol "Secreted to blood" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA028459: AB_10602490" "unprognostic (2.71e-2)" "unprognostic (5.64e-2)" "unprognostic (8.39e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.47e-2)" "unprognostic (3.87e-1)" "unprognostic (2.66e-2)" "unprognostic (1.04e-1)" "unprognostic (5.44e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.81e-4)" "unprognostic (5.59e-2)" "unprognostic (1.28e-2)" "unprognostic (8.47e-2)" "unprognostic (1.76e-1)" "unprognostic (6.14e-2)" "unprognostic (3.85e-1)" 0.3 0.1 0.0 0.0 0.0 0.1 3.1 0.0 0.0 26.1 1.0 1.9 3.9 3.1 4.7 20.8 1.6 0.2 1.4 0.1 0.0 7.4 1.2 3.7 0.0 0.1 0.1 0.1 2.4 0.0 2.1 0.0 0.1 7.5 0.9 0.2 8.0 0.5 0.2 15.0 17.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.5 0.0 0.3 2.4 32.7 0.1 0.2 0.8 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.8 13.8 0.0 35.9 0.0 0.0 1.7 0.0 0.1 0.0 4.2 0.0 0.0 13.0 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.0 0.8 0.4 0.0 0.0 1.3 8.4 9.4 0.9 16.8 0.0 0.3 41.2 0.0 0.9 0.8 0.0 0.0 0.0 15.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 6.4 1.5 0.0 0.0 30.3 239.7 137.3 8.6 0.1 2.5 1.3 0.7 2.8 146.1 69.9 0.0 0.2 0.1 23.3 0.0 8.8 0.0 36.9 0.5 0.6 1.8 0.0 0.0 1.0 0.0 1.8 3.1 6.5 0.0 0.3 0.0 0.2 0.0 0.0 0.0 4.2 38.7 0.0 0.4 0.0 0.0 2.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 10.9 2.7 0.0 0.1 62.5 91.7 1.6 20.9 0.0 0.0 0.4 3.5 0.0 0.2 2.4 29.1 0.0 0.7 0.8 8.2 45.2 EDN3 ET3 ENSG00000124205 "Endothelin 3" P14138 20 59300443-59325992 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Deafness, Disease variant, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 53.1;salivary gland: 68.3;vagina: 106.5" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 99.6;Distal enterocytes: 86.6;Paneth cells: 72.4;Proximal enterocytes: 93.0;Skeletal myocytes: 110.0;Squamous epithelial cells: 69.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 30900 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 37: Intestine - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (4.64e-3)" "unprognostic (7.87e-2)" "unprognostic (7.49e-2)" "unprognostic (2.88e-3)" "prognostic favorable (1.73e-4)" "unprognostic (1.58e-1)" "unprognostic (1.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (4.01e-2)" "unprognostic (4.08e-2)" "unprognostic (4.48e-1)" "unprognostic (6.11e-2)" "unprognostic (1.55e-1)" "unprognostic (6.40e-2)" 0.1 2.3 4.9 2.0 5.1 0.0 7.8 4.8 5.9 53.1 3.3 20.2 42.0 5.2 6.1 20.6 0.2 0.4 0.1 4.9 4.5 0.2 0.0 0.4 0.2 5.5 7.3 1.3 8.8 0.3 44.7 0.2 8.6 5.6 18.8 2.0 68.3 0.5 1.5 1.9 40.6 3.0 5.0 7.9 1.7 1.2 11.2 3.2 24.2 2.4 0.1 0.1 106.5 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.9 5.1 4.8 5.9 4.9 4.5 5.5 7.3 8.6 5.0 11.2 3.9 0.1 9.6 0.5 0.0 0.0 0.4 5.1 0.0 99.6 0.1 1.7 21.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 86.6 0.0 0.3 0.0 1.6 11.2 0.4 1.2 0.0 0.8 0.0 0.3 2.6 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.6 0.0 0.0 0.4 0.0 0.0 0.5 0.0 20.6 0.0 0.4 0.0 0.0 0.0 0.2 72.4 1.9 1.2 0.2 93.0 0.0 0.0 0.4 0.0 110.0 0.4 0.1 0.8 69.2 0.3 0.0 0.3 0.1 15.9 0.3 EFCAB12 C3orf25 ENSG00000172771 "EF-hand calcium binding domain 12" Q6NXP0 3 129401321-129428651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.6;fallopian tube: 19.7" "Group enriched" "Detected in some" 4 "Early spermatids: 29.6;Endometrial ciliated cells: 31.9;Late spermatids: 20.1;Respiratory ciliated cells: 46.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 1.5;RPTEC TERT1: 1.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 8.9" "HPA037694, HPA057532" Uncertain Supported Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nuclear bodies, Midbody ring" "HPA037694: AB_10672605, HPA057532: " "unprognostic (2.06e-3)" "unprognostic (1.87e-2)" "unprognostic (2.96e-2)" "unprognostic (4.34e-3)" "unprognostic (1.81e-1)" "unprognostic (7.59e-4)" "unprognostic (2.37e-2)" "unprognostic (2.60e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (1.81e-2)" "unprognostic (3.84e-1)" "unprognostic (1.20e-1)" "unprognostic (5.72e-2)" "unprognostic (2.27e-1)" "unprognostic (1.57e-2)" "unprognostic (4.59e-2)" 0.3 0.4 0.8 0.1 1.0 0.8 0.3 1.7 1.1 1.1 12.6 0.1 0.0 0.3 0.8 0.0 19.7 0.2 0.3 1.4 1.5 0.8 1.2 1.7 0.1 4.9 7.0 1.0 0.6 1.7 3.6 0.1 3.2 3.0 0.0 1.6 0.2 0.2 0.0 0.1 0.3 0.0 3.6 0.4 0.7 6.9 2.4 0.2 1.2 0.0 0.2 0.0 0.1 1.0 0.1 0.7 0.2 0.7 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.2 0.2 1.5 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.4 0.3 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.4 0.6 0.7 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.0 1.7 1.1 1.4 1.5 4.9 7.0 3.2 3.6 2.4 1.0 0.2 3.2 1.7 0.3 0.5 0.5 0.1 0.8 0.0 0.4 0.7 0.4 1.3 1.5 1.8 0.0 2.1 0.0 0.3 0.1 0.0 0.2 29.6 31.9 0.7 0.5 0.0 0.0 2.7 0.2 0.1 0.5 3.1 1.9 0.0 0.1 0.0 1.1 0.1 5.0 0.8 0.3 2.0 0.0 0.0 20.1 0.3 0.3 0.0 0.0 0.1 1.2 1.0 0.0 0.1 0.0 0.0 0.0 0.2 0.9 0.0 0.9 46.0 5.6 0.0 0.5 0.6 6.8 2.7 0.7 0.3 0.0 0.3 0.3 0.0 0.2 EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.7;Cytotrophoblasts: 1365.8;Fibroblasts: 309.7;Syncytiotrophoblasts: 889.6" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 953.6;hTERT-RPE1: 2226.5;HUVEC TERT2: 4270.9;TIME: 3554.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" 240.5 55.7 57.0 57.2 82.8 0.2 115.3 57.1 88.8 54.9 180.7 74.6 22.5 73.2 128.4 51.5 134.8 140.4 187.8 47.5 75.6 57.4 12.9 150.1 27.2 80.8 121.1 175.1 29.2 17.6 22.6 329.7 65.5 58.4 91.0 42.8 87.7 161.2 14.7 55.2 45.3 93.5 72.2 42.4 46.9 8.0 71.0 16.8 139.1 93.8 21.2 203.9 77.3 71.9 358.4 3.1 8.5 0.3 320.9 217.1 0.8 208.1 233.7 25.2 20.5 0.0 18.0 0.5 140.4 234.3 22.1 323.4 1.6 234.6 8.9 1.0 1.0 0.3 87.4 0.2 843.2 0.3 0.6 953.6 117.5 21.9 260.9 2226.5 4270.9 0.5 1.2 0.2 99.2 36.7 2.6 0.5 4.2 0.1 0.8 0.2 0.3 0.9 9.8 7.3 2.0 0.4 284.6 105.0 0.7 8.1 289.8 1.5 3554.3 1.5 107.5 397.9 138.5 13.7 0.5 1.4 73.1 0.3 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 82.8 57.1 88.8 47.5 75.6 80.8 121.1 65.5 72.2 71.0 71.9 26.6 250.0 109.1 234.1 0.1 79.4 79.1 367.7 42.1 2.8 6.2 78.2 12.5 12.8 98.2 27.6 0.0 1365.8 0.4 0.0 9.8 36.2 0.5 2.2 38.9 73.5 0.0 0.0 1.0 25.6 173.0 309.7 6.1 2.1 2.5 3.9 48.5 0.7 94.9 0.0 4.7 0.0 40.7 0.8 33.9 0.9 42.6 3.2 17.8 6.5 0.6 137.3 0.0 2.5 0.8 2.8 0.0 0.0 1.5 24.2 0.0 14.7 88.8 4.7 0.0 7.0 28.7 0.4 1.8 6.0 31.7 889.6 5.0 61.3 0.0 6.2 EFEMP2 "FBLN4, UPH1" ENSG00000172638 "EGF containing fibulin extracellular matrix protein 2" O95967 11 65866441-65873592 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 122.8;Leydig cells: 93.5;Muller glia cells: 84.8;Peritubular cells: 107.2;Smooth muscle cells: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 125.8;BJ hTERT+: 159.7;fHDF/TERT166: 232.6;HSkMC: 155.3;hTERT-RPE1: 159.1;LHCN-M2: 134.5;U-138 MG: 114.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023270 Approved "Secreted to extracellular matrix" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA023270: AB_1848019" "unprognostic (3.13e-1)" "unprognostic (2.15e-3)" "unprognostic (3.23e-2)" "unprognostic (5.11e-2)" "unprognostic (8.57e-3)" "unprognostic (1.50e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.89e-2)" "unprognostic (9.12e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (8.33e-3)" "unprognostic (6.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.58e-2)" 38.4 18.0 19.8 13.8 21.1 2.8 29.5 18.8 26.7 46.6 22.1 39.6 9.3 55.2 8.3 12.8 35.8 33.5 61.6 19.1 20.4 26.8 7.0 32.1 9.1 24.9 20.0 47.0 19.9 26.8 15.2 22.4 21.4 31.1 6.5 5.9 17.4 35.2 21.2 14.9 16.2 32.3 20.3 16.1 20.6 8.2 21.4 5.6 39.1 22.0 5.0 33.1 30.7 19.1 0.5 0.2 2.1 47.3 54.3 108.0 0.8 125.8 159.7 48.1 44.8 0.0 4.3 0.7 9.3 232.6 0.7 0.9 0.0 1.3 12.1 5.4 0.1 1.1 3.2 8.0 89.1 0.0 0.4 155.3 0.4 18.9 1.0 159.1 28.5 1.0 0.3 8.0 134.5 0.4 0.2 20.7 1.6 0.2 0.6 0.4 0.3 3.2 1.6 0.6 0.7 14.1 0.2 1.3 1.5 6.6 1.5 10.0 64.6 114.2 24.7 52.6 0.6 10.9 0.7 0.3 42.6 0.8 19.7 0.0 0.1 0.5 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.7 0.0 0.0 0.0 0.2 19.8 21.1 18.8 26.7 19.1 20.4 24.9 20.0 21.4 20.3 21.4 19.1 30.8 35.3 7.4 29.0 1.5 13.5 38.9 33.9 8.6 7.7 10.2 27.6 46.0 15.7 11.4 18.4 0.0 2.4 2.3 0.3 7.9 28.7 15.6 3.4 57.1 27.9 0.0 0.4 1.1 0.2 3.9 122.8 2.6 4.1 0.0 74.3 42.8 1.8 9.8 6.7 2.9 0.3 4.1 3.5 19.1 33.3 93.5 3.0 24.9 9.4 0.7 84.8 2.1 9.5 1.6 2.6 0.1 107.2 1.4 30.1 0.2 21.2 9.0 4.8 39.5 41.1 113.2 35.9 3.3 1.1 10.1 5.9 2.4 78.5 0.3 14.2 EFNA1 "ECKLG, EPLG1, GMAN, LERK1, TNFAIP4" ENSG00000169242 "Ephrin A1" P20827 1 155127876-155134899 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 472.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 942.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 11.4;naive CD8 T-cell: 5.9" "Lineage enriched" "Detected in single" 23 "T-cells: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 266.5;HaCaT: 95.5;SiHa: 156.9;SK-BR-3: 227.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069549 Approved "Secreted to blood" NA Yes 2800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA069549: " "unprognostic (5.14e-2)" "unprognostic (3.04e-3)" "unprognostic (5.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.59e-1)" "unprognostic (2.47e-2)" "unprognostic (1.78e-2)" "unprognostic (5.80e-3)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (2.00e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" 43.2 24.0 25.6 4.9 30.0 1.3 64.7 27.2 33.9 31.7 21.8 42.5 57.9 23.7 28.5 54.7 23.2 24.5 47.1 25.5 25.9 73.8 472.8 86.7 8.1 31.0 29.0 17.5 53.6 29.7 19.5 109.9 29.8 79.5 51.6 7.8 66.6 22.1 18.5 123.1 69.3 13.4 27.8 8.6 40.7 4.1 27.6 21.0 79.9 38.6 12.5 36.9 55.5 35.2 15.1 5.9 0.9 11.5 2.1 0.1 266.5 0.0 0.5 0.2 0.3 13.9 32.0 0.0 26.3 0.0 9.0 95.5 6.6 35.3 0.2 9.8 2.2 0.1 19.0 76.1 0.9 0.2 1.5 4.9 84.5 0.0 30.2 7.3 53.6 0.9 2.8 0.3 0.0 52.2 0.3 1.1 1.7 52.3 17.7 6.1 1.5 9.3 66.4 22.4 9.8 14.2 156.9 227.1 6.0 48.8 51.1 0.0 6.7 0.1 9.1 0.6 1.5 2.3 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 1.0 0.7 0.0 0.3 11.4 5.9 0.4 0.4 0.0 0.0 0.0 1.6 25.6 30.0 27.2 33.9 25.5 25.9 31.0 29.0 29.8 27.8 27.6 35.2 116.8 198.7 113.1 0.7 2.3 127.7 103.7 91.6 327.8 3.0 198.3 151.9 47.8 95.8 101.2 18.4 0.0 195.6 4.4 265.0 13.7 130.1 0.3 100.4 19.1 148.9 18.6 4.0 0.7 63.9 942.6 23.2 124.9 163.5 6.3 0.1 106.4 133.2 28.2 5.0 0.8 114.1 101.7 4.3 19.5 0.7 4.7 4.2 62.2 2.8 0.6 5.7 0.0 3.5 28.7 73.9 205.5 0.4 4.1 197.8 238.6 34.5 54.5 1.1 0.0 6.5 35.9 0.8 2.6 253.2 217.8 254.2 7.5 1.3 95.9 135.9 EFNA2 "ELF-1, EPLG6, LERK6" ENSG00000099617 "Ephrin A2" O43921 19 1285873-1301431 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.3;liver: 12.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.5;Cardiomyocytes: 4.9;Inhibitory neurons: 1.6;Oligodendrocyte precursor cells: 5.0;Paneth cells: 2.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.5;stomach cancer: 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 10.3;CACO-2: 6.2;Hep G2: 13.5;NTERA-2: 6.8;OE19: 6.0;REH: 6.8;SH-SY5Y: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067567 Approved Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "Mitochondria, Cytosol" "HPA067567: AB_2732771" "unprognostic (1.98e-1)" "unprognostic (3.26e-1)" "unprognostic (2.87e-3)" "unprognostic (1.96e-2)" "unprognostic (4.04e-2)" "unprognostic (3.90e-1)" "unprognostic (7.19e-2)" "unprognostic (2.34e-3)" "unprognostic (3.58e-2)" "unprognostic (6.82e-2)" "unprognostic (8.48e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-3)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-4)" "unprognostic (1.94e-1)" 0.0 0.0 1.6 1.5 1.7 0.0 0.0 1.2 1.3 0.1 0.3 9.9 9.9 0.0 0.0 0.4 0.0 3.5 0.0 1.4 2.0 0.4 12.9 0.0 0.0 1.7 3.0 0.0 0.1 0.2 0.3 0.2 1.1 0.0 4.4 0.6 0.0 0.0 0.2 0.1 12.3 0.0 1.9 0.0 0.2 0.6 3.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.2 10.3 3.1 0.0 0.0 3.7 0.2 0.0 0.0 0.0 6.2 0.1 0.0 1.8 0.0 0.0 0.0 4.8 0.0 0.0 0.0 1.4 0.0 0.0 13.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.1 0.1 0.1 0.0 1.4 0.0 0.1 6.8 6.0 0.0 6.8 1.0 0.1 0.0 0.4 0.0 13.3 0.7 0.0 0.2 3.5 0.4 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.6 1.7 1.2 1.3 1.4 2.0 1.7 3.0 1.1 1.9 3.1 1.4 0.1 0.0 0.0 1.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 1.0 0.0 2.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.2 0.0 EFNA4 "EPLG4, LERK4" ENSG00000243364 "Ephrin A4" P52798 1 155063737-155069553 "Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 30.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.1;Theca cells: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" CAB021350 Uncertain "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB021350: " "unprognostic (4.65e-2)" "unprognostic (8.07e-2)" "unprognostic (3.43e-2)" "unprognostic (7.04e-2)" "unprognostic (7.91e-2)" "unprognostic (4.81e-1)" "prognostic unfavorable (1.00e-5)" "unprognostic (1.37e-2)" "unprognostic (3.89e-2)" "unprognostic (6.17e-2)" "unprognostic (2.87e-2)" "unprognostic (7.97e-3)" "prognostic unfavorable (3.14e-4)" "prognostic favorable (3.60e-5)" "unprognostic (3.35e-2)" "unprognostic (1.97e-1)" "unprognostic (6.29e-2)" 3.7 12.0 3.2 4.5 3.3 1.3 9.4 3.3 3.4 11.1 4.5 11.7 10.5 6.5 12.4 18.6 4.9 5.2 3.5 3.3 3.0 6.9 8.3 4.5 5.1 3.6 3.4 9.9 5.7 7.9 2.5 4.5 3.5 9.1 12.1 0.9 13.1 4.3 1.3 30.2 10.7 4.3 3.4 6.5 5.9 2.3 3.3 3.8 6.2 1.8 7.3 4.8 14.2 3.5 11.4 8.5 20.4 30.4 11.8 7.5 17.0 5.1 9.6 9.7 9.0 12.5 18.5 14.6 28.2 5.1 7.7 26.2 12.3 7.6 3.9 6.9 3.7 1.4 7.7 17.8 4.3 3.3 22.0 4.5 23.2 4.9 5.7 8.4 19.7 11.9 6.2 9.5 5.5 25.2 7.5 8.3 37.6 43.3 17.5 26.0 8.1 14.3 15.2 9.6 4.9 22.3 10.1 37.1 4.5 14.7 24.3 10.2 10.2 5.8 17.0 11.7 7.8 9.7 11.0 14.6 5.5 7.8 5.9 0.1 10.1 7.3 7.7 9.2 8.0 22.9 8.5 8.8 8.3 17.3 11.8 8.1 10.9 3.9 13.7 25.2 8.9 6.6 3.2 3.3 3.3 3.4 3.3 3.0 3.6 3.4 3.5 3.4 3.3 3.5 2.5 0.0 6.3 2.0 9.0 25.1 8.6 21.2 19.4 0.2 20.7 15.6 1.3 8.6 12.1 16.5 0.0 9.2 12.3 23.9 1.9 32.4 0.1 4.9 4.5 6.8 3.0 2.1 0.2 14.0 86.1 8.4 3.6 6.6 1.3 15.6 5.7 3.6 12.8 0.0 0.2 18.7 8.2 6.3 6.8 0.4 7.8 5.3 17.8 1.0 5.9 5.6 4.1 0.0 0.8 21.5 37.0 5.7 2.2 21.2 38.3 4.4 6.5 0.2 0.0 1.7 6.0 0.5 4.1 15.4 32.7 9.9 7.2 73.3 28.3 10.8 EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 806.1;Endothelial cells: 436.5;Hepatic stellate cells: 511.5;Hofbauer cells: 290.3;Spermatogonia: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Cell line enhanced" "Detected in many" "EFO-21: 183.9;HUVEC TERT2: 329.0;RPMI-8226: 136.8;TIME: 312.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" 195.6 50.2 108.8 13.4 90.4 14.4 192.3 85.0 144.3 112.9 74.4 49.1 13.4 104.3 9.8 39.8 98.5 27.4 243.3 89.8 86.5 144.3 56.1 204.2 20.8 102.0 96.9 37.8 28.2 18.5 51.3 181.6 100.9 74.9 3.5 1.0 39.4 13.2 60.5 47.8 51.4 13.4 89.9 191.7 40.7 43.3 111.7 5.6 105.5 25.2 2.9 87.5 86.3 85.2 0.1 45.7 14.6 52.7 1.2 1.0 33.4 12.9 2.3 7.3 2.3 16.2 42.4 0.3 183.9 4.3 11.9 6.5 3.7 8.3 0.3 77.2 14.1 28.8 3.4 1.3 11.4 0.0 40.1 1.5 3.2 3.7 0.0 2.5 329.0 2.1 104.9 0.1 2.5 83.5 0.5 0.7 21.1 64.3 2.6 91.4 5.9 136.8 4.6 1.1 9.3 31.0 6.3 5.9 12.2 4.2 15.5 43.6 312.6 1.8 37.2 4.4 2.5 0.4 0.1 0.5 0.2 0.1 38.4 0.0 2.1 3.5 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.8 0.2 5.5 5.9 0.0 2.4 108.8 90.4 85.0 144.3 89.8 86.5 102.0 96.9 100.9 89.9 111.7 85.2 806.1 0.0 26.5 2.3 6.2 11.9 5.6 5.5 9.6 2.0 5.9 6.7 23.7 5.7 4.2 3.7 0.0 3.1 5.9 1.4 7.9 19.4 2.7 1.4 3.4 436.5 1.2 58.9 15.0 2.0 17.8 18.5 0.5 1.9 20.3 2.0 511.5 20.5 290.3 3.3 10.1 4.6 2.0 24.5 14.2 9.2 8.7 18.7 19.6 102.1 1.2 1.9 0.0 3.5 1.8 5.8 3.7 6.0 4.0 19.1 22.5 25.2 0.2 2.3 13.1 13.0 18.4 18.9 179.8 2.7 9.5 6.0 2.9 4.8 0.5 3.5 EGFL8 "C6orf8, NG3" ENSG00000241404 "EGF like domain multiple 8" Q99944 6 32164595-32168281 "Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 6.4;Granulosa cells: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 3.2;SK-MEL-30: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061173 Uncertain Approved "Nuclear speckles,Vesicles" "Secreted - unknown location" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nuclear speckles" "HPA061173: AB_2684443" "unprognostic (7.13e-2)" "unprognostic (1.86e-1)" "unprognostic (6.79e-3)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (7.60e-4)" "unprognostic (3.42e-2)" "unprognostic (2.49e-1)" "unprognostic (6.42e-3)" "unprognostic (1.97e-1)" "unprognostic (7.60e-3)" "unprognostic (8.11e-3)" "unprognostic (1.07e-4)" "unprognostic (1.11e-1)" "unprognostic (6.79e-2)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" 13.3 7.2 3.8 0.5 3.5 1.1 13.6 3.6 5.7 23.4 4.1 19.8 0.6 10.0 0.8 12.3 16.3 3.0 14.2 3.9 3.9 16.3 7.4 9.4 0.3 3.8 3.9 31.2 5.1 0.4 8.2 2.9 3.7 16.9 0.5 0.0 7.9 1.4 3.8 12.8 8.8 0.3 3.8 7.9 10.2 4.4 4.1 0.6 8.7 2.5 0.2 13.5 17.2 3.8 0.2 0.1 0.4 1.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.5 0.0 0.3 3.2 0.0 0.0 0.3 0.0 0.4 0.2 0.1 0.0 0.2 0.7 0.5 0.0 0.0 0.6 1.0 1.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 3.4 0.0 1.0 0.7 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 3.5 3.6 5.7 3.9 3.9 3.8 3.9 3.7 3.8 4.1 3.8 1.2 6.4 4.1 0.0 0.3 1.5 0.6 0.3 4.6 1.5 0.5 0.3 0.1 0.0 1.6 1.8 2.1 0.8 0.6 0.2 0.0 0.4 0.1 1.0 1.9 1.7 0.0 1.7 0.0 0.2 0.4 1.5 4.6 1.3 0.0 10.4 3.3 0.3 0.2 0.0 0.0 1.1 0.0 0.6 1.6 0.2 3.7 0.7 0.0 0.0 0.0 0.9 3.1 0.0 0.0 0.3 0.2 1.2 2.1 0.7 0.4 0.1 1.6 1.5 0.0 2.0 1.5 0.5 0.4 4.0 2.3 0.8 0.9 1.5 1.3 0.5 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 13 "A-431: 5282.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 88000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" 27.9 11.4 12.6 4.0 18.3 0.0 20.0 16.6 9.7 20.4 10.5 12.2 5.7 11.4 10.3 23.5 13.9 9.0 7.1 6.3 10.3 11.6 35.3 14.9 2.5 10.4 19.0 15.1 15.8 3.5 2.9 67.9 8.9 16.2 10.7 10.2 22.1 15.0 10.9 51.0 9.5 9.3 7.5 5.1 11.1 4.2 22.6 12.8 20.6 20.6 8.3 14.7 24.1 6.3 5282.1 61.9 16.5 22.4 102.7 63.5 16.7 47.9 68.7 30.8 23.8 11.5 54.2 2.7 11.4 43.8 130.7 197.1 0.4 230.2 37.1 2.2 3.6 0.1 27.3 3.4 27.0 0.0 0.2 31.2 205.4 74.1 409.9 45.5 4.0 0.0 0.0 0.5 68.0 3.0 0.1 0.1 5.1 21.2 30.4 0.1 9.1 0.2 38.1 52.6 0.8 20.0 42.7 50.6 9.3 16.8 4.9 12.0 15.6 27.1 7.2 215.7 45.8 0.1 4.8 3.1 37.9 1.6 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 18.3 16.6 9.7 6.3 10.3 10.4 19.0 8.9 7.5 22.6 6.3 16.4 96.1 49.9 147.6 1.2 85.8 77.1 101.5 116.1 3.5 12.1 30.4 11.1 47.1 50.6 22.0 6.2 287.9 0.0 45.9 0.0 32.9 4.9 25.9 57.2 12.5 4.2 8.0 1.2 24.3 37.1 91.6 22.4 39.8 0.0 50.6 6.8 79.5 28.3 0.0 107.5 21.6 48.8 7.7 11.6 5.8 128.3 1.9 17.8 40.3 1.6 90.0 0.0 63.3 1.4 54.8 19.9 133.5 0.0 75.4 14.1 13.4 21.7 3.8 78.9 251.2 34.7 2.4 2.5 73.3 89.9 376.8 2.2 41.9 24.9 55.8 EHBP1 "KIAA0903, NACSIN" ENSG00000115504 "EH domain binding protein 1" Q8NDI1 2 62673851-63046487 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 203.4;Early spermatids: 220.3;Excitatory neurons: 262.3;Inhibitory neurons: 245.4;Late spermatids: 495.6;Oligodendrocyte precursor cells: 226.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035468, HPA035469" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Cytosol "HPA035468: AB_10671513, HPA035469: AB_10601365" "unprognostic (5.39e-2)" "unprognostic (1.63e-3)" "unprognostic (8.78e-2)" "unprognostic (3.83e-3)" "unprognostic (1.43e-1)" "unprognostic (1.57e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.78e-1)" "unprognostic (1.95e-1)" "unprognostic (3.33e-2)" "unprognostic (3.14e-1)" "unprognostic (3.13e-3)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (1.95e-8)" 30.0 17.2 15.1 10.7 16.3 6.4 17.4 27.7 19.3 29.0 11.7 41.9 9.7 31.1 7.9 29.5 21.3 20.4 11.7 20.0 16.5 17.1 53.9 11.6 8.8 13.3 22.1 48.0 15.9 15.2 12.2 11.9 14.1 16.0 14.2 20.9 15.7 18.6 8.0 13.0 14.9 30.0 10.9 8.1 17.5 37.4 22.6 13.4 14.4 13.1 10.2 18.1 21.6 16.2 49.7 66.9 26.8 16.4 46.1 89.0 27.2 43.6 42.4 31.6 25.9 80.4 36.2 34.2 15.4 79.8 47.5 29.1 35.1 30.5 51.9 36.3 16.5 29.7 22.9 95.2 31.5 17.5 21.5 40.9 54.1 31.6 61.9 31.3 20.5 26.7 20.6 19.1 51.1 19.4 20.0 10.9 26.3 40.8 26.2 17.8 33.8 14.9 20.8 16.1 29.6 23.6 35.1 25.9 43.0 28.5 12.6 17.0 15.2 33.3 34.4 55.8 23.0 21.5 16.2 32.7 33.3 26.3 69.4 0.2 2.2 2.5 4.1 2.4 4.0 6.3 4.2 3.9 3.7 4.9 4.2 3.6 0.8 3.4 1.3 2.4 2.5 2.2 15.1 16.3 27.7 19.3 20.0 16.5 13.3 22.1 14.1 10.9 22.6 16.2 29.0 38.5 18.8 203.4 10.4 15.6 12.0 27.1 43.3 39.7 10.5 12.8 15.2 22.8 20.7 14.7 4.2 10.9 9.9 5.3 15.6 22.1 220.3 10.3 45.4 19.9 16.2 8.8 262.3 40.5 30.1 36.6 9.2 12.1 2.5 15.2 30.0 59.6 5.0 18.5 245.4 5.4 6.1 8.6 11.4 495.6 58.4 7.6 10.6 119.0 6.5 20.1 13.4 226.7 98.7 41.7 5.0 40.3 9.6 13.9 11.4 15.1 14.5 17.8 6.6 33.1 19.4 53.7 31.1 55.4 14.2 2.9 12.7 18.2 8.1 13.1 EHMT1 "bA188C12.1, EHMT1-IT1, Eu-HMTase1, FLJ12879, FLJ40292, KIAA1876, KMT1D" ENSG00000181090 "Euchromatic histone lysine methyltransferase 1" Q9H9B1 9 137618992-137870016 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 167.0;Plasma cells: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060022, HPA074729" Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Nuclear bodies" "HPA060022: AB_2684190, HPA074729: " "unprognostic (1.18e-1)" "unprognostic (1.64e-1)" "unprognostic (1.19e-2)" "prognostic favorable (6.56e-4)" "unprognostic (1.03e-1)" "prognostic favorable (8.91e-4)" "unprognostic (5.87e-2)" "unprognostic (1.74e-2)" "unprognostic (4.18e-3)" "unprognostic (2.34e-1)" "unprognostic (2.26e-2)" "unprognostic (7.55e-3)" "unprognostic (2.01e-2)" "unprognostic (6.58e-3)" "unprognostic (4.24e-1)" "unprognostic (7.12e-3)" "unprognostic (7.75e-2)" 17.7 18.3 11.0 22.3 12.0 30.5 18.2 16.0 12.3 17.0 13.8 19.3 18.8 21.5 9.7 19.1 18.1 14.0 13.5 8.6 8.3 11.0 14.4 15.8 29.6 10.7 10.2 19.9 14.9 13.8 12.9 15.0 11.1 16.2 13.1 13.7 18.4 13.9 31.4 19.3 19.6 15.1 4.4 25.9 18.2 40.5 12.7 22.9 19.6 15.0 21.2 18.3 16.2 19.9 26.7 52.3 57.4 53.2 23.9 24.6 48.1 34.5 21.4 24.7 20.2 34.7 32.5 81.6 32.7 26.0 29.9 56.2 34.8 37.8 19.2 45.3 24.7 34.4 54.2 22.4 20.9 52.9 39.5 22.6 25.9 29.9 28.9 18.1 41.3 30.1 52.6 27.5 17.9 61.9 62.5 26.3 56.0 42.1 34.8 79.3 49.5 47.2 20.7 47.7 50.6 41.1 65.4 45.4 15.3 40.6 51.1 42.0 39.0 28.9 29.5 44.8 33.2 17.2 52.0 67.0 21.3 27.6 32.0 19.5 16.2 21.2 18.0 14.3 11.3 16.4 15.6 15.6 12.9 23.0 14.9 13.5 28.8 17.3 15.6 23.3 14.2 9.7 11.0 12.0 16.0 12.3 8.6 8.3 10.7 10.2 11.1 4.4 12.7 19.9 34.3 19.2 19.2 130.6 64.9 17.5 23.4 26.9 32.5 39.7 30.5 26.7 31.5 25.8 24.7 22.0 52.1 23.8 36.9 24.4 3.9 24.1 86.8 29.3 44.8 29.9 28.1 31.7 74.4 21.0 21.8 27.6 45.3 40.6 18.9 55.8 18.9 41.7 19.7 50.5 76.4 22.2 10.2 25.8 18.1 167.0 35.8 26.9 12.4 71.2 31.2 19.7 51.5 64.3 104.0 25.4 30.3 37.6 170.6 34.9 20.7 14.3 22.6 46.8 13.1 34.7 28.5 80.4 51.9 35.3 20.2 26.5 38.9 81.3 23.8 28.8 EHMT2 "BAT8, C6orf30, Em:AF134726.3, G9A, KMT1C, NG36/G9a" ENSG00000204371 "Euchromatic histone lysine methyltransferase 2" Q96KQ7 6 31879759-31897687 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 13.3;NTERA-2: 19.3;U-266/84: 16.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050550, HPA060259" Supported Supported "Nucleoplasm,Nuclear speckles" "Intracellular and membrane" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Nucleoplasm "HPA050550: AB_2681170, HPA060259: AB_2684234" "unprognostic (3.11e-2)" "unprognostic (2.72e-1)" "unprognostic (4.39e-2)" "unprognostic (1.92e-2)" "unprognostic (5.44e-2)" "unprognostic (3.51e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (3.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.89e-2)" "unprognostic (1.88e-1)" "unprognostic (9.78e-3)" "unprognostic (8.72e-2)" "unprognostic (1.84e-1)" "unprognostic (2.25e-1)" "unprognostic (9.03e-2)" 8.6 9.6 0.5 0.3 0.4 1.0 8.7 0.4 0.5 15.1 0.2 12.9 2.4 19.8 1.7 10.1 12.8 0.0 5.7 0.4 0.4 7.1 4.6 7.3 1.0 0.4 0.5 16.1 7.8 0.6 12.8 0.7 0.4 10.3 0.3 0.6 9.5 1.3 5.5 9.3 10.5 1.4 0.4 11.5 9.4 12.6 0.5 1.5 10.3 0.4 1.0 13.1 11.3 0.4 0.0 4.5 7.8 0.0 3.4 1.8 5.0 3.5 2.8 3.9 3.2 0.0 0.0 0.0 7.6 5.7 4.0 0.0 0.0 8.6 1.8 5.4 11.8 0.0 0.0 0.1 0.0 13.3 0.0 4.6 1.4 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 9.4 0.0 19.3 0.0 0.0 8.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.3 6.5 3.1 0.0 0.0 3.8 4.1 3.1 6.9 0.0 11.0 16.1 3.8 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.4 0.4 0.5 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.4 16.9 16.0 12.0 22.9 20.3 8.4 6.3 11.9 26.2 60.6 15.9 17.8 6.6 17.2 18.9 25.8 41.7 24.6 13.4 9.2 7.9 15.7 41.5 10.1 19.1 16.1 22.6 19.3 16.6 12.2 15.0 16.0 13.3 11.8 14.5 33.8 22.1 7.5 16.3 38.7 24.4 16.4 12.2 12.9 7.3 60.0 27.4 12.1 19.6 9.4 19.9 26.8 25.7 20.1 23.9 10.8 9.1 23.0 16.5 6.2 12.5 10.1 10.8 48.2 26.3 16.3 15.0 20.8 33.7 23.5 11.1 5.6 18.3 19.9 19.0 5.2 EIF2AK1 "HRI, KIAA1369" ENSG00000086232 "Eukaryotic translation initiation factor 2 alpha kinase 1" Q9BQI3 7 6022247-6059175 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein synthesis inhibitor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Cytotrophoblasts: 219.1;Erythroid cells: 422.0;Syncytiotrophoblasts: 371.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016496, CAB022082, HPA061675" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm Cytosol "CAB022082: , HPA016496: AB_1848057, HPA061675: AB_2684583" "unprognostic (7.15e-3)" "unprognostic (2.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.91e-1)" "unprognostic (6.70e-2)" "unprognostic (9.69e-3)" "prognostic unfavorable (6.99e-4)" "unprognostic (2.36e-1)" "unprognostic (2.54e-1)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (1.99e-1)" "unprognostic (5.45e-2)" "unprognostic (9.02e-2)" "unprognostic (1.06e-2)" 27.2 39.4 28.1 27.7 28.9 105.9 35.9 30.6 36.1 29.0 34.9 48.8 37.1 25.0 37.4 30.4 31.0 23.8 33.8 28.1 30.6 43.8 65.1 30.3 35.2 30.5 28.9 29.3 44.3 78.0 25.9 52.3 31.6 35.0 47.3 29.0 46.8 24.2 38.3 33.3 37.2 23.8 29.1 26.6 49.1 19.5 29.8 43.6 39.3 34.4 40.4 27.2 22.4 33.7 144.5 90.5 71.2 108.8 66.4 59.6 92.4 73.0 66.8 64.2 80.8 83.7 96.2 112.5 77.4 81.3 115.5 100.4 93.1 67.1 82.2 69.8 140.3 115.9 91.6 127.3 54.3 100.8 102.0 48.1 82.8 60.7 64.9 67.7 69.4 88.1 189.0 106.8 61.4 146.5 55.6 128.6 88.5 84.6 99.7 120.0 74.6 134.0 82.3 70.3 87.3 156.5 139.3 186.6 63.8 98.6 141.0 122.4 65.9 37.0 134.2 65.3 78.2 106.5 114.8 115.6 73.9 129.8 108.7 11.1 6.9 17.3 8.2 5.5 5.6 12.3 6.5 9.3 6.9 9.5 7.5 6.6 3.7 10.2 6.2 6.0 8.9 4.8 28.1 28.9 30.6 36.1 28.1 30.6 30.5 28.9 31.6 29.1 29.8 33.7 23.1 38.5 43.7 14.4 42.8 23.8 34.9 34.3 41.5 29.7 52.5 34.9 49.6 45.8 37.7 44.1 16.7 219.1 52.5 57.1 66.5 55.0 8.8 59.5 42.3 27.5 38.5 422.0 21.8 44.8 82.1 29.7 64.7 48.1 20.8 44.9 21.0 63.2 53.8 32.0 21.9 68.7 54.9 39.0 29.9 16.1 34.5 65.2 24.9 13.1 62.8 46.4 70.0 19.1 26.9 53.0 47.0 37.6 60.1 43.3 47.5 66.1 48.3 26.5 13.1 32.0 26.0 33.7 34.5 45.5 22.4 371.0 38.0 57.1 52.7 32.3 EIF2B4 "DKFZP586J0119, EIF-2B, EIF2B, EIF2Bdelta" ENSG00000115211 "Eukaryotic translation initiation factor 2B subunit delta" Q9UI10 2 27364352-27370457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 196.4;Late spermatids: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032234, HPA039993, HPA068855" Approved Approved "Nuclear membrane,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear membrane" "Actin filaments" "CAB032234: AB_668909, HPA039993: AB_2676790, HPA068855: " "unprognostic (2.26e-2)" "unprognostic (1.41e-1)" "unprognostic (3.00e-1)" "unprognostic (7.55e-2)" "unprognostic (2.37e-1)" "unprognostic (4.63e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (3.64e-2)" "unprognostic (2.18e-1)" "unprognostic (3.56e-3)" "unprognostic (1.11e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (5.46e-8)" "unprognostic (1.79e-1)" "unprognostic (1.70e-1)" "unprognostic (8.76e-2)" "unprognostic (1.67e-2)" 21.4 24.8 23.3 15.2 24.3 10.7 20.7 24.0 23.8 21.3 22.5 31.7 14.6 21.0 16.9 27.8 20.3 13.4 28.0 23.2 23.7 18.2 21.5 18.1 17.2 24.4 24.3 19.8 31.4 20.4 20.3 18.8 24.0 25.4 18.4 19.3 24.6 20.8 51.8 29.3 18.4 22.8 23.2 18.6 24.7 38.1 24.4 18.9 18.1 35.2 22.9 24.1 21.4 24.1 38.7 59.8 44.3 34.6 58.4 42.7 48.4 41.0 43.7 55.7 37.3 89.2 16.9 49.7 38.7 48.7 46.6 27.6 62.5 50.8 36.2 37.4 40.7 61.7 39.3 104.5 51.1 58.2 23.0 41.3 51.1 69.2 51.6 40.4 53.3 37.2 59.5 24.9 53.0 35.2 28.8 61.7 49.1 59.8 38.9 52.9 69.9 43.2 50.0 32.7 34.3 37.4 34.1 53.8 42.6 39.6 31.3 23.4 52.8 40.1 47.0 35.4 49.7 50.9 65.7 74.7 33.9 47.9 38.6 56.6 53.9 38.8 32.1 48.1 44.6 31.1 31.6 32.6 52.5 25.3 30.2 32.9 7.7 30.8 52.2 38.6 43.8 43.2 23.3 24.3 24.0 23.8 23.2 23.7 24.4 24.3 24.0 23.2 24.4 24.1 19.9 12.8 14.8 9.8 17.5 35.9 18.9 32.0 15.4 22.6 28.0 18.7 33.0 14.3 27.0 22.0 66.7 40.9 27.8 23.4 19.6 29.0 196.4 22.3 23.9 19.9 24.0 8.2 6.6 33.4 25.0 24.6 14.8 17.6 31.6 16.9 25.7 34.4 24.3 10.1 6.5 24.8 28.5 20.7 28.0 299.6 23.3 16.5 23.2 2.8 29.5 23.2 16.5 6.0 8.8 26.7 27.1 24.8 28.4 21.2 23.0 27.6 24.9 58.9 19.7 17.0 34.9 71.5 38.9 14.5 34.8 46.1 24.3 23.8 20.5 14.4 ELANE "ELA2, HLE, HNE, NE" ENSG00000197561 "Elastase, neutrophil expressed" P08246 19 851014-856247 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 91 "bone marrow: 3894.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.7;Fibroblasts: 16.2;Langerhans cells: 11.1;Leydig cells: 6.2;Melanocytes: 7.2;Suprabasal keratinocytes: 7.4" "Group enriched" "Detected in some" 7 "pancreatic cancer: 3.5;stomach cancer: 3.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 4.0;neutrophil: 12.1" "Group enriched" "Detected in many" 9 "granulocytes: 12.1;monocytes: 4.0" "Cell line enriched" "Detected in some" 91 "THP-1: 3105.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015409, HPA066836, HPA073774" Enhanced "Secreted to blood" NA NA 370000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015409: AB_831596, HPA066836: AB_2685733, HPA073774: " "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-3)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.43e-2)" "unprognostic (3.92e-1)" "unprognostic (6.38e-3)" "unprognostic (5.80e-1)" "unprognostic (2.54e-2)" "unprognostic (4.06e-2)" "unprognostic (3.48e-2)" "unprognostic (1.19e-10)" "unprognostic (6.27e-3)" "unprognostic (4.00e-2)" "unprognostic (2.76e-2)" "unprognostic (4.75e-3)" 3.4 1.0 0.3 0.0 0.3 3894.9 3.4 0.1 0.7 0.5 0.2 2.0 0.4 1.0 0.0 1.1 1.4 0.1 4.0 0.3 0.2 0.7 3.3 19.4 0.6 0.1 0.2 0.5 0.5 0.0 1.2 0.8 0.1 2.9 0.0 0.0 2.4 0.1 1.5 5.4 1.8 0.1 0.1 42.6 1.4 0.4 0.2 6.3 3.1 0.0 0.0 2.1 1.0 0.2 2.0 0.1 0.0 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 3105.0 0.0 0.0 0.1 0.0 1.3 0.0 0.2 0.8 0.0 34.0 0.0 0.0 4.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 27.2 0.3 0.3 0.1 0.7 0.3 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.9 0.0 0.0 0.0 0.3 8.7 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.7 0.0 4.2 0.1 0.0 1.3 16.2 0.0 0.1 0.0 0.0 0.7 0.9 0.2 0.0 0.1 0.0 0.0 3.4 11.1 0.0 6.2 1.1 7.2 0.0 0.9 0.0 1.0 0.0 0.1 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.2 0.0 0.0 7.4 0.0 0.7 0.2 0.0 0.0 ELAPOR1 "EIG121, KIAA1324, maba1" ENSG00000116299 "Endosome-lysosome associated apoptosis and autophagy regulator 1" Q6UXG2 1 109113679-109206781 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 156.7;salivary gland: 166.1;stomach 1: 88.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;dendritic cells: 1.2;Hofbauer cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 65.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 65.2" "Cell line enhanced" "Detected in some" "MCF7: 20.8;SCLC-21H: 16.8;SK-BR-3: 17.6;T-47d: 59.1;U-87 MG: 12.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029869, HPA070749" Enhanced Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA029869: AB_10794320, HPA070749: AB_2686304" "unprognostic (2.10e-1)" "unprognostic (1.42e-2)" "unprognostic (1.99e-2)" "prognostic favorable (2.14e-7)" "unprognostic (4.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-3)" "prognostic favorable (5.69e-5)" "unprognostic (2.79e-2)" "prognostic favorable (2.16e-4)" "unprognostic (3.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.22e-16)" "unprognostic (2.46e-1)" "unprognostic (1.75e-1)" "unprognostic (5.64e-2)" "unprognostic (8.02e-2)" 0.8 3.2 3.6 4.1 4.4 0.5 56.7 0.0 4.9 70.1 0.0 28.3 45.5 12.8 9.7 1.6 23.9 5.6 0.2 4.4 13.2 0.1 0.2 5.1 2.5 0.2 0.1 0.1 156.7 9.2 32.9 0.2 0.7 48.6 27.8 0.4 166.1 0.3 0.0 3.9 35.3 1.1 0.0 0.8 88.2 18.3 10.0 0.8 9.0 0.1 1.9 0.4 0.1 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.0 0.5 0.6 0.7 1.3 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 1.0 0.0 0.0 0.5 20.8 0.2 0.3 0.5 0.0 0.1 0.1 0.3 1.1 0.1 0.0 16.8 0.4 0.1 17.6 0.0 0.1 59.1 0.0 0.4 0.0 2.1 0.2 0.2 1.3 3.6 0.0 12.4 0.0 0.1 0.0 0.1 0.0 4.6 0.0 7.6 0.4 7.5 3.2 0.0 0.1 3.3 1.5 65.2 0.5 0.0 0.0 9.8 2.2 3.6 4.4 0.0 4.9 4.4 13.2 0.2 0.1 0.7 0.0 10.0 1.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 70.4;Fibroblasts: 115.9;Leydig cells: 110.6;Peritubular cells: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 97.6;BJ: 143.7;fHDF/TERT166: 205.6;U-2197: 817.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 2900000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" 147.2 21.6 11.6 40.8 14.3 0.1 94.2 19.9 17.6 100.2 24.3 57.6 8.8 73.6 18.4 53.0 70.7 76.7 184.1 13.1 15.3 12.8 13.4 214.1 14.5 15.4 20.1 37.0 90.9 2.8 24.9 58.9 13.8 106.4 11.3 2.8 66.9 35.1 17.9 91.3 40.6 90.0 14.9 40.9 63.2 13.1 14.0 5.1 48.4 16.9 4.5 85.3 84.3 17.9 0.0 2.0 0.8 0.0 97.6 0.6 0.6 143.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 205.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.5 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.6 0.6 8.3 0.8 0.8 0.4 58.0 1.0 0.0 0.0 28.0 68.9 0.0 1.2 0.1 10.0 0.6 0.0 0.0 0.2 0.3 817.9 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 14.3 19.9 17.6 13.1 15.3 15.4 20.1 13.8 14.9 14.0 17.9 34.6 0.0 6.4 34.9 0.1 11.0 13.5 33.9 4.0 2.8 0.9 1.1 9.7 2.8 4.3 7.3 2.1 0.1 0.3 0.2 0.0 0.3 3.5 3.5 70.4 28.4 1.8 0.0 4.6 3.9 0.3 115.9 7.1 2.3 0.0 0.2 47.2 4.2 0.5 6.7 8.1 1.3 0.0 0.6 20.4 7.5 110.6 1.2 14.2 23.4 0.0 15.9 0.0 14.1 18.5 1.1 0.2 148.2 0.4 1.4 0.0 0.1 3.0 0.8 0.0 12.2 34.1 1.1 1.2 2.1 10.9 0.1 1.2 0.6 0.2 1.1 ELP2 "FLJ10879, STATIP1, StIP" ENSG00000134759 "Elongator acetyltransferase complex subunit 2" Q6IA86 18 36129444-36180557 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, tRNA processing" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002996, CAB020835" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 31: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "CAB020835: , HPA002996: AB_1857552" "unprognostic (5.51e-2)" "unprognostic (1.29e-1)" "prognostic favorable (5.41e-4)" "unprognostic (6.66e-3)" "unprognostic (4.33e-2)" "unprognostic (4.54e-1)" "unprognostic (2.23e-1)" "unprognostic (5.89e-2)" "unprognostic (1.92e-1)" "unprognostic (6.74e-3)" "unprognostic (7.31e-3)" "unprognostic (7.07e-2)" "unprognostic (8.04e-2)" "unprognostic (1.91e-1)" "unprognostic (3.05e-2)" "unprognostic (1.14e-1)" "unprognostic (8.97e-2)" 17.7 20.7 12.1 12.3 13.2 13.2 35.3 12.4 11.9 23.5 12.3 19.1 15.2 27.3 31.0 15.9 28.8 20.3 23.6 11.4 14.2 18.9 46.2 16.6 19.9 12.1 12.1 48.6 24.4 24.8 20.7 20.8 12.6 29.4 16.2 21.2 19.1 26.3 32.4 21.5 14.0 22.5 12.2 16.7 16.5 22.2 13.4 23.6 21.8 32.3 23.3 22.5 16.9 16.0 23.7 16.7 30.8 27.8 42.7 63.9 33.9 47.9 69.3 39.6 52.5 17.6 21.5 49.6 32.6 40.4 26.5 32.9 39.7 35.8 55.8 22.6 21.1 19.2 27.4 31.0 46.6 63.0 19.6 52.3 40.2 39.4 63.6 59.5 45.0 33.8 32.9 25.4 42.4 28.4 30.6 27.0 36.7 18.2 12.6 48.7 37.0 34.9 35.7 54.4 24.2 46.3 45.1 17.6 73.0 44.0 22.5 31.2 26.8 35.6 20.5 13.2 24.8 30.4 25.6 46.2 30.0 33.2 31.3 22.0 12.1 10.0 12.6 17.6 17.9 20.0 17.0 15.0 17.6 16.3 21.5 18.9 2.2 22.2 24.8 17.5 18.4 14.0 12.1 13.2 12.4 11.9 11.4 14.2 12.1 12.1 12.6 12.2 13.4 16.0 25.0 48.1 28.8 34.3 46.3 32.9 49.4 33.8 39.9 50.1 42.1 28.6 48.5 22.8 29.2 35.0 43.8 39.5 45.9 10.9 29.4 26.4 55.0 29.9 33.1 29.4 24.7 21.7 61.7 22.2 42.3 39.2 17.3 29.5 36.7 39.9 24.7 75.3 22.8 33.7 60.7 20.3 20.3 28.0 24.8 90.4 43.5 20.8 23.2 34.7 39.1 26.9 41.2 52.3 77.4 18.7 12.1 36.5 34.2 60.9 24.3 19.0 36.5 45.4 6.6 40.8 30.6 40.0 33.2 25.0 36.7 39.8 39.7 28.0 26.9 50.7 ELP5 "C17orf81, DERP6" ENSG00000170291 "Elongator acetyltransferase complex subunit 5" Q8TE02 17 7251416-7259940 "Predicted intracellular proteins" "Transcription, Transcription regulation, tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 171.6" "Group enriched" "Detected in all" 4 "Early spermatids: 405.3;Late spermatids: 699.6;Spermatocytes: 226.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023279, HPA052411" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA023279: AB_1847613, HPA052411: " "unprognostic (3.73e-2)" "unprognostic (9.21e-3)" "unprognostic (1.24e-1)" "unprognostic (2.39e-3)" "unprognostic (7.72e-2)" "unprognostic (1.22e-1)" "unprognostic (7.70e-2)" "unprognostic (1.53e-1)" "unprognostic (7.83e-3)" "unprognostic (1.60e-2)" "prognostic favorable (2.62e-4)" "unprognostic (1.36e-1)" "unprognostic (1.83e-1)" "unprognostic (8.07e-2)" "unprognostic (2.71e-1)" "unprognostic (1.62e-1)" "unprognostic (2.30e-2)" 30.6 47.9 21.1 10.0 22.0 14.1 26.7 22.0 23.8 30.0 22.0 36.4 11.5 31.8 12.8 27.9 28.7 9.3 59.7 21.0 21.8 39.6 57.1 22.7 16.7 21.7 21.6 33.7 28.0 19.9 39.7 10.4 21.6 35.4 10.8 18.9 26.1 11.8 57.3 21.2 31.2 17.8 21.2 35.0 29.0 171.6 21.9 22.9 29.3 77.9 16.9 30.9 24.8 21.6 22.4 61.7 27.3 24.9 46.8 36.8 11.9 19.5 23.1 30.7 28.2 62.0 14.3 44.0 21.1 31.3 53.7 16.4 69.6 46.1 22.0 27.4 98.2 40.7 20.5 57.3 23.2 29.2 15.4 26.2 34.0 21.0 41.1 19.4 26.5 54.9 28.6 11.5 48.4 37.5 74.4 55.4 22.5 23.4 42.5 63.0 30.6 23.9 34.5 20.7 13.3 26.4 38.0 11.5 30.9 27.0 16.3 20.9 30.4 17.6 20.6 34.1 31.7 13.3 19.4 51.8 32.0 28.1 23.3 28.6 30.7 16.1 32.3 37.8 41.0 39.3 28.9 30.1 37.4 39.5 30.2 35.9 5.3 38.7 26.1 45.9 44.7 28.6 21.1 22.0 22.0 23.8 21.0 21.8 21.7 21.6 21.6 21.2 21.9 21.6 30.4 9.6 11.7 10.7 38.3 22.0 47.7 47.8 27.9 21.5 27.8 36.6 64.3 12.8 39.9 46.0 20.9 36.1 45.1 29.7 97.8 38.3 405.3 20.5 28.1 26.5 41.6 14.1 9.4 13.6 78.1 28.6 9.7 21.5 7.0 30.1 18.2 24.2 41.4 28.6 9.7 37.0 57.0 13.5 28.8 699.6 34.2 22.8 21.4 10.3 29.0 32.7 29.9 10.6 10.5 19.3 32.9 33.1 26.7 73.5 46.9 107.0 23.1 33.6 39.5 27.1 35.9 226.4 40.8 21.0 21.7 57.9 29.9 29.0 46.5 51.6 ELSPBP1 "E12, EDDM12, HE12" ENSG00000169393 "Epididymal sperm binding protein 1" Q96BH3 19 47994632-48025154 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "epididymis: 2828.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 22.0;Cone photoreceptor cells: 16.7;Early spermatids: 32.0;Horizontal cells: 18.5;Late spermatids: 28.8;Muller glia cells: 20.4;Rod photoreceptor cells: 120.5" "Cancer enhanced" "Detected in single" "melanoma: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HMC-1: 10.1;NB-4: 5.5" "Not detected" "Not detected" "HPA044256, HPA050341" Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 3: HMC-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA044256: AB_2678879, HPA050341: AB_2681097" "unprognostic (1.51e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2828.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 32.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 18.5 0.1 0.0 0.0 0.0 0.0 28.8 0.6 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 120.5 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EMC10 "C19orf63, HSM1, HSS1, INM02" ENSG00000161671 "ER membrane protein complex subunit 10" Q5UCC4 19 50476400-50490871 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 185.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 193.0;PC-3: 137.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053905, HPA062723" Approved "Secreted to blood" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "HPA053905: AB_2682303, HPA062723: " "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (9.86e-3)" "unprognostic (1.65e-1)" "unprognostic (6.94e-2)" "unprognostic (8.38e-3)" "unprognostic (3.23e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-1)" "unprognostic (2.99e-1)" "prognostic favorable (4.39e-4)" "unprognostic (5.01e-2)" "prognostic favorable (6.64e-6)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (1.28e-1)" "unprognostic (2.44e-1)" 24.3 63.9 29.1 11.4 41.5 19.7 27.6 38.4 38.2 34.1 46.7 36.1 23.8 38.8 15.3 36.0 32.0 13.5 50.7 27.2 29.4 76.3 63.0 32.1 9.7 38.8 35.0 49.6 55.2 44.3 106.4 9.5 36.0 38.3 7.1 8.7 55.7 16.9 185.8 31.7 36.0 6.6 32.7 27.8 47.8 45.6 36.0 6.9 82.4 9.0 6.8 31.0 27.3 49.5 66.2 80.1 3.0 30.8 8.8 10.8 0.8 62.9 11.4 5.4 5.9 0.7 44.4 21.6 0.8 11.3 9.9 55.1 3.7 10.3 2.0 84.2 193.0 4.6 33.9 0.0 14.7 19.1 123.2 13.3 11.3 5.6 4.3 5.2 13.5 18.5 42.7 44.9 11.3 46.0 30.3 0.6 0.3 26.0 137.6 51.7 9.7 71.7 25.0 59.2 48.5 107.9 92.5 29.6 36.1 3.6 31.0 34.8 26.2 3.8 83.1 23.0 34.4 49.5 132.7 17.9 24.8 13.2 30.8 6.2 6.9 8.1 5.0 5.6 4.3 6.4 5.3 5.3 5.3 8.5 6.2 6.0 3.0 3.1 4.3 7.0 4.7 5.2 29.1 41.5 38.4 38.2 27.2 29.4 38.8 35.0 36.0 32.7 36.0 49.5 30.3 64.1 111.1 15.7 65.6 29.7 53.4 60.9 31.3 82.3 72.5 53.8 11.3 81.5 64.0 69.9 81.3 129.5 71.0 103.6 23.5 181.8 177.7 52.1 49.4 46.0 212.2 21.7 7.9 112.3 155.0 46.6 71.9 79.8 53.2 80.3 55.6 79.4 133.8 37.0 11.8 117.7 59.0 109.2 36.7 39.1 69.0 67.7 83.6 9.4 103.1 101.2 90.6 44.2 78.3 114.4 144.9 115.1 80.2 66.4 158.2 66.8 28.6 71.7 6.6 93.3 43.7 18.0 56.2 50.3 31.3 151.0 67.4 78.5 130.5 66.5 EMC4 "FLJ90746, MGC24415, PIG17, TMEM85" ENSG00000128463 "ER membrane protein complex subunit 4" Q5J8M3 15 34225013-34230156 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053440 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA053440: AB_2682151" "unprognostic (8.99e-2)" "unprognostic (1.59e-1)" "unprognostic (7.68e-2)" "unprognostic (3.29e-2)" "unprognostic (9.23e-2)" "unprognostic (1.29e-3)" "unprognostic (3.25e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (1.78e-3)" "unprognostic (1.33e-1)" "unprognostic (2.20e-2)" "unprognostic (2.52e-1)" "unprognostic (5.42e-2)" "unprognostic (4.20e-2)" "unprognostic (2.96e-1)" "unprognostic (1.97e-2)" 76.1 68.1 83.8 48.8 86.5 58.7 68.4 90.3 103.7 69.3 92.0 69.1 55.1 67.0 102.9 78.3 67.8 52.3 86.4 87.6 88.8 67.9 91.3 57.3 55.4 87.2 85.2 66.2 90.7 83.0 60.3 59.2 88.4 62.3 58.2 65.4 79.0 63.7 214.4 63.9 57.1 58.8 86.9 49.1 69.8 49.4 85.7 58.1 60.6 136.7 54.2 59.2 71.4 95.2 123.1 248.2 103.9 135.1 133.2 119.6 95.0 137.7 156.9 166.0 143.4 162.0 106.1 48.5 177.7 160.0 145.6 229.4 107.0 135.3 118.7 148.3 103.7 91.9 219.4 154.8 161.0 139.8 87.8 121.4 126.3 121.4 136.0 118.1 139.8 144.6 117.0 186.6 147.1 137.9 109.9 149.9 116.9 165.0 163.5 102.0 94.7 138.3 161.0 186.9 137.1 166.4 101.7 148.3 77.6 74.8 99.3 164.7 106.5 151.3 103.8 131.8 142.7 162.8 251.5 122.0 184.5 164.1 131.1 256.5 158.6 176.9 154.5 173.9 170.0 237.2 170.6 185.8 162.6 187.7 172.2 168.8 88.5 197.8 200.2 166.6 216.1 277.6 83.8 86.5 90.3 103.7 87.6 88.8 87.2 85.2 88.4 86.9 85.7 95.2 75.3 54.5 67.7 8.8 67.9 91.5 103.7 206.5 55.8 35.8 83.7 104.1 58.7 58.6 132.4 66.2 18.8 150.6 62.5 39.5 125.2 180.3 121.8 67.6 55.1 86.1 52.0 38.7 14.1 172.3 173.6 87.8 36.7 69.1 88.0 63.2 64.2 78.6 113.7 18.5 15.4 62.8 166.8 48.5 73.2 27.4 100.6 56.5 101.4 13.1 87.9 98.4 76.2 15.1 16.9 184.0 65.4 90.7 117.9 89.6 71.8 117.5 133.3 42.8 85.5 81.4 123.2 169.7 91.9 60.2 110.0 141.7 68.8 69.7 66.4 125.4 EMC9 "C14orf122, CGI-112, FAM158A" ENSG00000100908 "ER membrane protein complex subunit 9" Q9Y3B6 14 24138959-24141591 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 155.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 63.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078254 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA078254: " "unprognostic (3.09e-2)" "unprognostic (4.23e-2)" "unprognostic (1.28e-1)" "unprognostic (3.39e-2)" "unprognostic (3.07e-1)" "unprognostic (2.51e-1)" "unprognostic (3.14e-2)" "unprognostic (5.71e-2)" "unprognostic (9.46e-2)" "prognostic favorable (2.43e-4)" "unprognostic (1.15e-2)" "unprognostic (2.74e-1)" "unprognostic (1.17e-2)" "unprognostic (1.81e-1)" "unprognostic (3.33e-1)" "unprognostic (1.29e-2)" "unprognostic (1.99e-1)" 10.4 30.2 9.5 2.7 9.5 6.0 10.4 9.7 10.9 11.4 11.7 14.9 9.9 11.0 4.8 14.5 11.5 2.5 17.6 9.5 10.4 22.2 26.8 10.1 4.2 9.9 9.1 13.3 20.8 5.0 31.9 3.0 10.1 19.5 3.4 12.5 14.4 5.2 39.6 16.6 14.4 3.1 8.8 17.3 13.8 16.3 9.6 6.1 14.4 18.4 3.6 13.2 11.9 9.1 14.1 32.6 9.0 25.0 4.7 2.5 8.3 8.7 7.0 12.5 12.5 14.2 10.5 11.6 7.5 7.0 9.7 12.6 7.4 13.8 7.4 9.3 18.0 2.7 13.2 63.3 5.8 10.3 5.7 3.4 5.6 6.8 11.9 10.0 14.1 16.3 2.7 14.9 9.9 33.0 10.2 8.8 10.4 14.3 23.7 6.4 22.3 12.1 9.8 16.7 15.7 12.7 16.3 28.9 7.7 4.4 16.1 5.2 7.1 5.4 15.0 8.0 14.7 18.7 17.7 13.5 8.4 4.4 8.8 0.8 4.2 3.5 3.7 2.3 4.2 4.6 5.1 5.0 4.3 4.8 2.5 3.4 0.4 3.4 2.1 10.2 7.5 3.5 9.5 9.5 9.7 10.9 9.5 10.4 9.9 9.1 10.1 8.8 9.6 9.1 14.1 0.0 7.0 3.9 17.3 18.1 10.4 24.7 24.5 46.4 23.3 23.1 19.7 17.2 15.5 23.9 18.8 33.0 17.3 22.1 56.7 17.6 83.3 12.6 12.3 12.3 21.0 32.6 6.1 11.7 24.2 16.6 6.1 12.9 5.1 24.2 8.6 26.1 30.5 11.8 6.6 29.6 24.4 14.0 19.6 155.7 11.5 11.4 16.0 3.7 15.4 21.2 9.2 4.0 3.2 9.7 14.0 21.8 21.6 17.9 75.9 61.0 18.6 54.4 13.1 15.5 18.5 20.9 5.6 18.1 23.9 24.5 13.4 32.0 30.9 10.3 EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Adipocytes: 409.0;Endothelial cells: 261.7;Hepatic stellate cells: 175.3;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" NA NA 470000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA005928: AB_1078735" "unprognostic (8.01e-2)" "unprognostic (2.13e-4)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (2.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (1.03e-4)" "unprognostic (3.65e-1)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-2)" "unprognostic (3.10e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.75e-3)" "unprognostic (2.36e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" 46.3 20.2 6.7 9.6 7.1 0.2 38.2 7.1 11.2 37.1 7.8 10.3 6.8 27.9 9.9 12.7 19.2 31.4 38.5 6.3 7.5 79.7 7.5 48.4 6.6 8.1 7.0 6.9 6.2 19.2 9.6 0.8 9.0 12.7 8.1 1.5 9.2 25.6 18.5 9.0 8.3 38.8 7.0 3.5 8.2 2.3 9.4 8.7 43.6 40.2 4.9 24.9 13.9 7.4 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.1 0.0 30.6 0.0 0.0 0.1 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 7.1 7.1 11.2 6.3 7.5 8.1 7.0 9.0 7.0 9.4 7.4 409.0 6.4 6.0 0.3 14.0 16.6 0.5 0.1 6.2 0.1 2.1 3.0 14.1 0.0 0.7 0.0 0.0 0.1 1.7 0.0 0.0 0.1 0.7 0.6 0.6 261.7 0.0 8.0 1.3 0.0 0.0 16.2 0.0 0.3 0.0 0.1 175.3 1.1 0.2 0.0 0.2 0.0 0.0 5.5 21.4 1.3 1.2 1.7 16.0 111.5 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.4 2.6 1.0 0.0 0.2 0.0 0.4 0.0 5.8 21.4 0.2 0.5 1.1 14.6 0.3 2.4 0.7 0.0 1.0 EMID1 "EMI5, EMU1, hEmu1" ENSG00000186998 "EMI domain containing 1" Q96A84 22 29205896-29259597 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.5;lymphoid tissue: 54.8" "Cell type enhanced" "Detected in many" "Astrocytes: 92.1;Granulosa cells: 32.7;Oligodendrocyte precursor cells: 51.8;Theca cells: 151.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 23.1;glioma: 7.8;ovarian cancer: 10.9;thyroid cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HEL: 28.8;NB-4: 102.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000592 Uncertain "Secreted in other tissues" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "HPA000592: AB_1078737" "unprognostic (2.20e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-2)" "unprognostic (7.80e-3)" "unprognostic (2.40e-2)" "unprognostic (1.42e-1)" "unprognostic (3.46e-1)" "unprognostic (6.25e-3)" "unprognostic (3.75e-2)" "unprognostic (2.33e-1)" "unprognostic (5.24e-3)" "unprognostic (1.18e-1)" "unprognostic (1.36e-3)" "unprognostic (1.59e-1)" "unprognostic (1.76e-1)" "unprognostic (3.09e-2)" "unprognostic (1.08e-1)" 2.6 29.0 34.5 4.2 35.0 14.8 2.5 27.7 49.5 6.5 24.4 5.7 5.1 10.0 1.7 1.3 10.4 4.8 2.3 36.8 29.4 15.0 3.3 13.0 7.5 30.1 30.4 7.0 14.0 12.4 2.0 4.9 28.3 6.1 3.4 0.3 3.6 3.9 0.8 6.3 8.3 2.3 27.0 54.8 7.7 2.3 27.8 4.8 13.2 0.3 2.3 4.9 2.2 32.4 0.0 0.2 4.9 10.5 0.0 0.0 0.7 0.0 0.0 0.4 0.3 5.7 0.7 0.0 4.7 0.1 0.0 0.0 2.5 0.1 0.0 11.5 8.6 28.8 0.1 1.1 0.7 4.1 2.2 0.3 0.2 0.2 0.0 0.0 0.0 6.4 2.5 0.0 0.0 8.0 0.2 102.0 1.1 0.1 0.4 0.0 0.2 11.3 0.0 0.1 13.2 6.3 0.4 0.1 0.2 0.8 4.2 5.4 0.0 0.0 8.0 0.0 0.1 0.5 0.0 0.0 0.0 14.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 34.5 35.0 27.7 49.5 36.8 29.4 30.1 30.4 28.3 27.0 27.8 32.4 0.4 0.0 2.5 92.1 0.1 2.8 1.0 0.1 0.0 1.7 5.3 3.9 0.7 4.3 0.6 0.0 0.0 0.1 0.2 0.0 0.0 1.2 0.2 10.8 22.6 6.2 0.0 18.5 5.6 1.3 0.1 11.8 0.5 20.0 11.4 32.7 11.4 2.1 0.3 0.0 6.2 0.4 0.0 0.3 5.2 0.5 3.1 0.6 0.0 10.3 0.6 1.1 0.0 51.8 1.0 0.4 0.0 1.9 1.0 1.9 0.1 1.9 0.0 0.4 0.0 17.5 4.0 0.1 1.5 0.0 2.0 0.3 1.1 151.0 0.3 0.4 EMILIN1 "DKFZp586M121, gp115" ENSG00000138080 "Elastin microfibril interfacer 1" Q9Y6C2 2 27078615-27086403 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 64.5;Fibroblasts: 111.3;Hepatic stellate cells: 45.0;Leydig cells: 85.1;Peritubular cells: 167.3;Sertoli cells: 72.3;Smooth muscle cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.2;BJ hTERT+: 65.0;HHSteC: 99.0;HSkMC: 109.6;SH-SY5Y: 129.4;U-138 MG: 63.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002822 Supported "Secreted to extracellular matrix" NA NA 4300000 "Cluster 49: Eosinophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA002822: AB_1078738" "unprognostic (3.14e-1)" "unprognostic (2.44e-2)" "unprognostic (3.92e-2)" "unprognostic (3.42e-2)" "unprognostic (3.26e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-1)" "unprognostic (2.89e-2)" "unprognostic (4.10e-3)" "unprognostic (3.07e-2)" "unprognostic (1.85e-1)" "unprognostic (7.97e-2)" "prognostic unfavorable (8.13e-9)" "unprognostic (8.96e-3)" "unprognostic (3.77e-2)" "unprognostic (1.20e-2)" "unprognostic (5.70e-3)" 55.5 55.7 6.9 47.0 7.1 1.9 43.6 6.4 7.1 139.8 4.6 223.5 24.9 206.3 7.4 23.3 129.2 35.4 68.9 5.9 7.5 55.5 42.4 100.7 11.7 13.0 7.6 172.4 21.2 1.4 26.9 16.2 9.5 96.4 7.9 0.3 17.5 52.1 10.3 19.1 72.0 50.3 8.3 118.1 87.6 16.9 10.4 2.4 29.7 2.6 2.2 142.9 70.2 8.6 0.9 0.7 5.9 0.9 35.8 49.0 1.1 98.2 65.0 20.7 29.7 0.5 0.8 0.6 0.9 56.6 0.1 0.9 0.2 0.2 3.8 3.1 1.3 1.8 0.5 43.9 99.0 1.5 27.0 109.6 0.1 14.2 0.0 0.2 0.2 1.3 1.0 0.9 4.3 1.1 0.9 28.8 3.2 0.5 0.7 15.6 1.3 1.2 0.0 0.4 1.6 129.4 0.3 0.5 1.1 0.4 0.4 2.5 11.9 63.6 2.0 7.6 0.4 1.7 1.8 1.1 0.7 1.3 17.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 6.9 7.1 6.4 7.1 5.9 7.5 13.0 7.6 9.5 8.3 10.4 8.6 5.2 0.0 0.5 6.5 0.4 3.3 0.2 0.0 0.0 0.6 0.8 7.1 2.9 1.5 0.0 0.0 0.0 1.6 0.6 0.2 0.0 0.4 0.6 1.9 64.5 6.3 0.0 4.0 0.2 0.4 1.5 111.3 0.5 1.3 4.5 0.2 45.0 1.0 6.4 0.0 0.3 0.3 0.0 2.5 5.8 10.0 85.1 4.1 10.6 8.4 0.5 3.6 0.0 0.5 0.3 0.8 0.1 167.3 0.8 0.2 0.5 1.0 0.0 1.1 72.3 35.3 52.4 0.6 0.4 0.4 3.1 2.9 1.3 10.7 0.1 0.1 EMILIN2 "FLJ33200, FOAP-10" ENSG00000132205 "Elastin microfibril interfacer 2" Q9BXX0 18 2847006-2916003 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 76.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 98.0;Hofbauer cells: 61.1;Kupffer cells: 52.9;Langerhans cells: 99.7;Macrophages: 97.5;monocytes: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 5.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 48.2;BEWO: 37.8;HL-60: 37.8;HMC-1: 60.6;HSkMC: 26.1;SuSa: 25.7;THP-1: 36.7;U-2197: 46.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 25.7" HPA064576 Supported "Secreted to extracellular matrix" NA NA 840000 "Cluster 41: Basophils - Cellular respiration" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA064576: AB_2732717" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (7.91e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-3)" "unprognostic (9.91e-3)" "prognostic unfavorable (6.30e-4)" "unprognostic (2.01e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.49e-1)" "unprognostic (3.15e-3)" "unprognostic (3.72e-2)" "unprognostic (2.96e-1)" 13.0 1.3 1.2 17.2 2.2 11.3 5.1 4.8 1.7 5.3 2.2 2.8 1.6 6.4 0.8 2.4 4.7 5.9 6.8 0.7 1.2 1.1 1.5 11.9 2.4 8.1 4.4 5.9 1.4 76.0 0.4 21.9 5.8 1.0 3.3 0.1 2.3 1.2 0.8 2.7 2.2 8.4 6.6 3.9 1.6 1.8 7.4 2.9 1.6 2.4 2.0 8.0 4.0 10.6 0.2 0.4 2.9 0.0 48.2 19.9 37.8 7.9 0.0 1.4 2.4 5.6 0.1 0.0 0.6 19.3 0.5 0.1 1.0 0.0 2.6 0.0 2.6 0.5 0.2 0.4 1.6 37.8 60.6 26.1 0.0 1.5 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.1 10.4 4.9 0.4 0.1 0.1 2.5 0.0 0.1 0.2 0.4 0.2 0.2 0.3 1.4 25.7 0.0 36.7 0.4 0.0 5.2 46.7 0.4 0.0 0.0 0.0 3.1 9.1 1.0 5.5 1.1 0.3 0.4 0.8 0.3 0.2 0.4 0.3 1.1 0.3 0.2 0.4 1.1 1.5 0.7 0.7 0.3 0.4 1.2 2.2 4.8 1.7 0.7 1.2 8.1 4.4 5.8 6.6 7.4 10.6 6.8 3.2 6.7 0.0 13.7 5.7 3.3 0.5 0.6 0.1 2.8 3.0 15.7 1.5 5.3 3.7 0.0 4.7 14.5 2.8 1.9 2.7 2.3 19.3 98.0 8.8 3.0 6.7 0.5 1.1 11.9 31.4 5.6 46.0 46.3 5.7 2.9 0.5 61.1 0.0 1.2 4.9 0.0 52.9 99.7 2.3 15.2 97.5 5.4 2.8 51.0 0.0 7.2 11.1 9.1 2.4 7.9 1.2 2.7 3.5 1.5 1.7 4.0 0.2 0.0 2.3 8.7 4.9 5.5 0.4 4.0 2.9 9.6 14.7 5.1 2.8 EMILIN3 "C20orf130, dJ620E11.4, EMILIN5" ENSG00000183798 "Elastin microfibril interfacer 3" Q9NT22 20 41359962-41366818 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 53.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 17.7;Granulosa cells: 7.6;Microglial cells: 4.7;Oligodendrocyte precursor cells: 3.5;Peritubular cells: 4.9;Skeletal myocytes: 3.2" "Group enriched" "Detected in many" 5 "glioma: 10.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.3;HAP1: 11.1;NTERA-2: 7.0;SCLC-21H: 13.0" "Region enriched" "Detected in single" 30 "cerebellum: 3.3" "Region enriched" "Detected in single" 4 "spinal cord: 4.1" "HPA044034, HPA059912, HPA078559" Enhanced Approved "Golgi apparatus,Microtubules,Cytokinetic bridge" "Secreted to extracellular matrix" Yes NA 1200000 "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" "Microtubules, Cytokinetic bridge" "HPA044034: AB_2678783, HPA059912: AB_2684158, HPA078559: " "unprognostic (1.66e-4)" "unprognostic (1.85e-2)" "unprognostic (2.50e-2)" "unprognostic (2.14e-1)" "unprognostic (2.65e-1)" "unprognostic (2.15e-2)" "unprognostic (1.71e-1)" "unprognostic (7.66e-2)" "unprognostic (2.18e-3)" "unprognostic (2.57e-1)" "unprognostic (6.54e-2)" "unprognostic (7.66e-2)" "unprognostic (3.13e-7)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.97e-1)" "unprognostic (9.62e-2)" 0.6 1.4 2.5 0.1 2.4 0.0 3.5 2.3 3.8 8.6 1.8 4.9 0.6 2.3 53.6 0.8 4.2 0.3 7.8 2.1 2.2 1.0 0.6 0.3 0.1 3.7 2.7 8.9 0.2 0.1 1.8 0.0 3.0 6.7 0.3 0.0 1.0 9.9 0.9 3.9 1.7 0.9 2.5 0.1 2.0 1.7 2.6 0.5 0.3 2.6 0.2 2.3 4.7 3.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 11.1 0.0 0.2 0.0 1.3 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.0 1.3 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.4 2.3 3.8 2.1 2.2 3.7 2.7 3.0 2.5 2.6 3.0 0.6 0.0 0.0 0.7 0.0 0.9 0.2 0.0 0.0 0.3 1.2 2.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 17.7 0.4 0.0 0.0 1.1 0.0 0.0 0.8 0.0 0.7 0.0 7.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 1.8 0.1 0.0 4.7 0.0 0.1 0.0 3.5 0.1 0.0 1.2 4.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 3.2 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 ENAM AIH2 ENSG00000132464 Enamelin Q9NRM1 4 70628744-70646824 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 7.5;heart muscle: 6.5;kidney: 9.0;skeletal muscle: 4.9" "Group enriched" "Detected in some" 4 "Melanocytes: 33.8;Plasma cells: 13.4" "Group enriched" "Detected in some" 5 "pancreatic cancer: 0.6;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-266/70: 1.2;U-266/84: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA 23000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.52e-2)" "unprognostic (2.80e-3)" "unprognostic (1.87e-1)" "unprognostic (1.02e-2)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (7.94e-3)" "unprognostic (4.73e-2)" "unprognostic (2.06e-1)" "unprognostic (9.06e-4)" "unprognostic (1.01e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.81e-14)" "unprognostic (1.26e-1)" "unprognostic (2.56e-1)" "unprognostic (2.12e-1)" "unprognostic (1.45e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 7.5 0.0 0.3 2.4 6.5 0.0 0.0 9.0 0.5 0.3 0.0 0.0 0.0 0.0 3.6 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.9 0.0 0.2 0.2 0.0 0.1 1.7 0.6 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.1 2.8 0.0 3.7 0.0 0.0 0.0 0.0 3.9 1.0 4.4 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 2.6 0.3 0.1 33.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 13.4 0.0 0.0 4.1 0.0 0.2 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.1 0.0 ENDOG ENSG00000167136 "Endonuclease G" Q14249 9 128818500-128822676 "Plasma proteins, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 135.2" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 111.4;Late spermatids: 147.4;Respiratory ciliated cells: 115.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021335, HPA021830" Approved "Intracellular and membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA021335: AB_1848151, HPA021830: AB_1848152" "unprognostic (1.35e-1)" "unprognostic (3.41e-1)" "unprognostic (4.86e-2)" "prognostic favorable (5.12e-4)" "unprognostic (2.51e-1)" "unprognostic (3.95e-1)" "unprognostic (6.56e-2)" "unprognostic (2.64e-2)" "unprognostic (4.90e-1)" "unprognostic (6.97e-2)" "unprognostic (8.35e-3)" "unprognostic (1.03e-1)" "prognostic favorable (1.06e-7)" "unprognostic (1.69e-2)" "unprognostic (1.81e-1)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" 11.2 18.8 19.7 2.9 20.0 4.4 11.9 23.7 25.1 9.3 27.0 16.8 12.5 9.3 1.8 17.5 12.6 1.7 52.2 20.1 22.5 24.3 52.9 9.9 3.3 23.4 20.8 8.1 22.5 12.0 13.7 3.6 19.5 14.9 5.7 2.0 14.9 7.0 135.2 13.6 11.5 3.0 20.3 9.2 18.4 20.6 22.6 3.8 11.9 59.1 3.1 11.8 11.0 22.9 14.2 15.3 3.9 20.7 10.0 8.5 17.5 13.4 6.9 12.4 8.6 9.3 11.2 4.6 11.9 8.8 7.7 39.6 12.5 11.8 2.2 9.0 22.4 8.0 14.6 16.7 4.5 24.8 29.3 8.9 14.1 7.5 5.1 7.6 9.6 15.2 25.4 7.1 7.9 20.9 19.4 51.1 9.7 24.6 56.4 22.9 4.5 48.2 18.8 5.1 34.0 33.8 30.0 27.2 7.4 2.6 26.1 12.2 9.8 8.7 5.2 12.5 10.2 22.2 3.3 8.9 17.5 17.6 9.1 0.0 1.1 0.7 1.3 2.0 1.2 1.5 1.3 0.6 1.8 2.8 1.2 1.4 0.0 1.3 0.9 3.6 0.6 0.6 19.7 20.0 23.7 25.1 20.1 22.5 23.4 20.8 19.5 20.3 22.6 22.9 19.0 9.6 5.5 13.1 11.4 8.8 26.9 12.8 6.2 14.0 28.7 21.7 0.6 20.0 16.8 23.9 4.2 31.9 26.9 55.1 101.8 6.0 97.1 111.4 15.1 9.3 14.4 16.8 4.6 7.9 34.4 14.9 21.4 30.1 1.3 93.0 10.0 80.3 20.0 11.8 8.3 27.2 18.3 17.7 7.7 147.4 18.6 15.6 10.6 4.7 6.4 37.2 10.3 3.0 7.8 7.8 24.1 18.8 11.0 18.4 52.0 108.2 115.1 13.1 6.6 23.7 19.0 74.9 6.6 19.1 14.5 10.1 14.5 44.5 36.6 23.3 ENDOU "P11, PP11, PRSS26" ENSG00000111405 "Endonuclease, poly(U) specific" P21128 12 47709734-47725567 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 82.9;vagina: 31.0" "Cell type enhanced" "Detected in some" "Adipocytes: 6.9;Glandular and luminal cells: 9.6;Squamous epithelial cells: 5.2;Suprabasal keratinocytes: 9.1;Syncytiotrophoblasts: 34.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.2;SK-BR-3: 4.9;SuSa: 4.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012388, HPA067448" Enhanced "Secreted in other tissues" NA NA 14000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "HPA012388: AB_1854860, HPA067448: AB_2685843" "unprognostic (2.61e-2)" "unprognostic (4.92e-1)" "unprognostic (2.44e-2)" "unprognostic (1.25e-2)" "unprognostic (1.09e-1)" "prognostic favorable (6.29e-4)" "unprognostic (6.50e-2)" "unprognostic (5.49e-2)" "unprognostic (2.07e-2)" "unprognostic (1.55e-1)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" 1.8 0.1 2.5 0.1 2.8 0.2 1.7 2.6 3.1 19.5 1.8 0.7 0.1 0.5 1.0 82.9 0.9 0.5 0.6 2.8 2.1 1.1 0.1 0.7 0.3 2.5 2.6 1.8 0.2 0.0 0.5 2.5 2.7 0.4 0.1 0.1 23.2 0.2 0.5 21.1 0.4 0.5 2.2 0.3 0.6 0.3 2.7 0.1 0.9 0.1 8.8 0.7 31.0 2.3 0.0 0.0 0.0 0.0 0.3 1.1 0.7 0.2 0.9 0.8 0.7 0.1 0.0 2.2 0.5 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.9 0.0 4.6 0.1 0.0 0.1 0.2 0.0 0.6 0.1 1.2 1.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.8 2.6 3.1 2.8 2.1 2.5 2.6 2.7 2.2 2.7 2.3 6.9 0.0 0.0 2.0 0.1 1.7 0.2 0.0 0.0 0.2 0.4 0.4 1.2 0.0 0.7 0.0 0.0 1.0 0.0 0.1 0.0 0.1 0.1 2.4 0.8 3.5 0.0 0.0 0.1 0.0 1.0 0.8 0.0 9.6 0.0 0.0 2.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.1 1.5 0.1 3.6 1.0 0.1 0.1 0.0 0.5 0.5 0.1 0.0 1.2 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.2 0.2 0.0 0.0 5.2 9.1 34.3 0.0 0.2 0.0 0.1 ENHO "C9orf165, UNQ470" ENSG00000168913 "Energy homeostasis associated" Q6UWT2 9 34521043-34522990 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 16 "brain: 475.8;choroid plexus: 256.0" "Cell type enhanced" "Detected in many" "Astrocytes: 71.2;Muller glia cells: 145.1;Oligodendrocyte precursor cells: 28.6" "Cancer enhanced" "Detected in many" "glioma: 44.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "myeloid DC: 28.1" "Lineage enriched" "Detected in many" 8 "dendritic cells: 28.1" "Cell line enhanced" "Detected in many" "AN3-CA: 16.7;NTERA-2: 22.9;SCLC-21H: 11.6;SH-SY5Y: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042575 Approved "Secreted in brain" NA NA 4240000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "HPA042575: AB_10794914" "unprognostic (2.63e-2)" "unprognostic (9.53e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (3.71e-4)" "unprognostic (1.30e-1)" "unprognostic (7.51e-2)" "unprognostic (9.93e-2)" "unprognostic (1.34e-2)" "unprognostic (5.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.78e-4)" "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (6.47e-2)" "unprognostic (1.87e-1)" "unprognostic (5.50e-2)" "unprognostic (8.76e-2)" 1.5 0.8 385.2 0.9 422.3 0.8 4.4 360.6 475.8 2.0 256.0 5.9 2.2 0.4 0.2 0.4 2.8 0.7 2.1 344.8 364.6 1.0 23.5 1.5 0.3 400.8 408.7 0.6 1.6 2.3 11.4 0.1 373.1 8.9 2.3 5.7 1.7 0.5 1.0 5.5 4.7 0.2 380.4 0.6 5.5 16.0 459.9 0.2 0.5 0.5 0.2 1.3 1.5 321.5 0.2 1.2 6.5 16.7 0.2 0.0 0.4 0.0 0.0 2.6 2.7 0.7 0.3 2.9 4.5 0.0 5.3 0.2 7.6 0.5 0.6 0.4 7.4 0.0 0.1 1.6 0.2 0.0 3.6 0.0 0.1 0.0 0.3 0.0 0.0 5.4 0.0 2.4 0.6 0.4 0.0 0.0 22.9 1.2 4.7 0.1 0.1 0.4 0.6 0.0 11.6 11.0 0.9 5.2 0.6 0.8 0.3 2.2 0.0 0.5 2.4 0.1 0.1 1.4 1.7 0.1 0.6 0.0 3.9 0.0 0.2 0.0 0.0 3.5 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.0 3.6 1.0 1.5 0.0 0.7 385.2 422.3 360.6 475.8 344.8 364.6 400.8 408.7 373.1 380.4 459.9 321.5 0.2 0.0 0.5 71.2 0.3 2.8 2.3 0.0 0.0 4.6 12.0 11.7 0.7 1.5 0.1 0.0 2.1 0.2 0.3 0.0 0.0 0.8 1.0 0.2 7.0 0.7 1.8 1.7 6.4 0.2 0.4 15.5 1.1 0.1 0.0 2.3 1.1 4.8 2.9 5.0 13.6 0.0 0.0 1.0 9.3 5.4 0.3 8.3 1.8 3.7 7.8 145.1 0.0 28.6 7.2 0.0 15.0 0.4 0.0 8.4 0.3 0.5 0.0 4.1 0.0 0.4 0.8 0.7 14.9 0.1 3.1 0.0 0.7 0.1 0.4 0.7 ENOSF1 "FUCD, HSRTSBETA, rTS, TYMSAS" ENSG00000132199 "Enolase superfamily member 1" Q7L5Y1 18 670318-712662 "Enzymes, Predicted intracellular proteins" "Isomerase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 216.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047829 Enhanced NA NA 7300 "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA047829: AB_2680170" "prognostic favorable (2.27e-4)" "unprognostic (8.03e-2)" "unprognostic (2.02e-2)" "unprognostic (7.87e-3)" "unprognostic (1.85e-1)" "unprognostic (4.29e-2)" "unprognostic (6.48e-3)" "unprognostic (1.55e-2)" "unprognostic (3.50e-3)" "unprognostic (1.33e-3)" "unprognostic (2.44e-2)" "unprognostic (5.07e-3)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.36e-1)" "unprognostic (5.03e-2)" "unprognostic (1.31e-2)" 8.4 25.0 3.1 3.2 4.4 7.7 9.3 3.3 7.2 10.0 5.5 12.0 5.5 6.6 2.1 12.0 10.6 3.2 11.0 2.9 4.2 28.0 29.3 8.1 2.8 3.8 3.4 8.6 15.8 5.0 11.3 4.0 3.7 13.3 3.9 5.9 14.9 2.5 5.0 7.5 11.0 2.3 3.2 9.5 14.6 5.3 4.0 3.2 18.6 1.6 1.9 9.0 8.1 5.3 3.5 9.6 6.0 5.8 1.6 2.1 5.2 4.9 5.4 1.0 3.6 10.6 10.5 3.8 1.8 0.8 4.1 4.1 8.0 3.7 2.2 2.6 4.4 7.2 12.0 5.4 6.9 11.8 3.2 3.2 8.5 1.7 5.7 1.7 5.7 10.5 6.2 9.6 2.0 8.8 13.8 7.3 2.6 13.1 5.0 4.7 2.2 12.7 5.3 14.0 7.6 3.1 7.7 8.4 2.7 2.2 3.2 14.2 2.9 2.8 5.4 5.5 2.6 14.0 15.2 8.1 12.8 8.3 2.6 0.0 0.5 1.4 3.5 1.6 2.7 0.8 2.3 1.9 0.8 0.5 3.3 3.4 0.1 1.2 0.6 2.4 1.7 0.9 3.1 4.4 3.3 7.2 2.9 4.2 3.8 3.4 3.7 3.2 4.0 5.3 17.9 35.3 99.5 36.9 10.1 11.9 29.5 29.6 24.5 35.2 38.4 36.4 19.6 28.6 44.7 47.8 116.7 44.6 25.6 36.7 115.4 32.4 7.0 61.6 32.2 19.6 24.7 73.2 4.2 14.4 27.7 26.5 61.2 40.1 22.2 26.2 23.9 56.6 39.1 0.0 7.6 36.0 38.7 12.6 8.8 6.8 23.6 20.9 19.6 30.0 12.1 30.9 24.7 38.2 143.6 21.9 36.2 28.2 25.2 25.9 50.9 216.9 78.3 98.8 13.1 38.7 15.8 14.7 29.3 39.8 12.1 37.8 22.0 67.8 49.4 20.8 ENPP3 "B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3" ENSG00000154269 "Ectonucleotide pyrophosphatase/phosphodiesterase 3" O14638 6 131628442-131747418 "CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 32.1;intestine: 44.5" "Group enriched" "Detected in many" 5 "Endometrial ciliated cells: 160.0;Glandular and luminal cells: 387.2" "Cancer enriched" "Detected in many" 8 "renal cancer: 49.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 86 "basophil: 30.6" "Lineage enriched" "Detected in single" 86 "granulocytes: 30.6" "Group enriched" "Detected in some" 18 "HEL: 4.4;Hep G2: 14.6;HMC-1: 6.2" "Low region specificity" "Detected in some" "Region enriched" "Detected in single" 4 "spinal cord: 2.6" HPA043772 Enhanced "Secreted - unknown location" NA NA 1100000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA043772: AB_10795616" "unprognostic (2.74e-1)" "unprognostic (1.99e-2)" "unprognostic (1.84e-1)" "unprognostic (5.41e-3)" "unprognostic (6.07e-2)" "unprognostic (4.86e-5)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.80e-2)" "unprognostic (7.85e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" 1.2 6.2 0.4 1.1 0.4 0.1 6.6 0.9 0.5 32.1 0.2 9.3 16.2 3.8 1.2 0.5 2.3 1.3 0.1 0.3 0.5 10.0 5.0 0.9 0.5 0.5 0.6 0.5 0.1 0.3 0.1 0.1 0.5 2.4 8.4 0.3 18.1 15.6 0.1 0.6 44.5 0.8 0.4 0.3 0.5 0.8 0.5 9.6 0.3 0.2 0.4 0.4 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 4.4 0.0 14.6 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 30.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.4 0.9 0.5 0.3 0.5 0.5 0.6 0.5 0.4 0.5 0.4 0.4 0.0 1.1 5.2 0.2 0.0 2.6 0.7 1.2 0.2 1.0 0.6 0.3 0.0 2.5 0.0 0.0 0.0 0.2 9.2 1.9 0.0 1.6 160.0 46.3 1.4 0.0 2.1 2.1 0.0 0.1 0.5 0.0 387.2 36.0 0.1 0.7 1.7 0.1 0.0 4.1 1.5 0.0 0.6 1.1 0.4 1.2 1.5 1.8 2.8 0.0 0.1 1.0 3.5 0.9 0.0 1.9 0.7 0.3 2.7 53.3 9.1 5.4 0.1 0.0 0.2 1.0 2.5 0.8 0.0 0.6 0.1 2.2 0.1 4.9 1.1 ENPP6 MGC33971 ENSG00000164303 "Ectonucleotide pyrophosphatase/phosphodiesterase 6" Q6UWR7 4 184088706-184221230 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.4;kidney: 30.6;ovary: 12.5" "Cell type enhanced" "Detected in some" "Oligodendrocytes: 119.9;Peritubular cells: 35.3;Proximal tubular cells: 31.3;Theca cells: 23.9" "Cancer enriched" "Detected in some" 5 "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 3.2;SH-SY5Y: 3.6;U-266/70: 2.9;U-266/84: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042740, HPA069197" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 290000 "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA042740: AB_10793984, HPA069197: " "unprognostic (4.81e-4)" "unprognostic (1.47e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.56e-1)" "unprognostic (6.69e-3)" "unprognostic (3.07e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "unprognostic (7.60e-3)" "unprognostic (3.04e-2)" "unprognostic (1.72e-1)" "unprognostic (2.98e-2)" "unprognostic (2.82e-1)" "unprognostic (3.93e-3)" "unprognostic (2.01e-1)" 0.2 0.3 2.7 0.8 11.8 0.9 0.8 14.2 5.5 0.2 2.3 1.0 1.7 0.2 6.1 1.0 0.3 0.5 0.2 2.7 6.1 30.6 0.1 0.3 0.9 20.4 9.6 12.5 0.0 0.0 4.2 0.1 18.1 2.2 1.0 0.1 0.7 6.1 0.2 0.1 2.2 0.1 12.5 1.0 1.2 2.4 11.1 1.9 0.1 1.3 2.8 0.6 0.3 29.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 2.7 11.8 14.2 5.5 2.7 6.1 20.4 9.6 18.1 12.5 11.1 29.4 0.5 0.0 0.0 5.9 0.1 0.0 0.2 0.9 0.6 0.0 0.1 0.5 0.9 0.0 0.4 1.8 0.0 0.0 0.0 0.0 3.9 1.1 1.0 0.0 0.0 0.5 0.0 0.0 4.3 0.2 0.0 8.7 0.0 0.0 5.7 0.0 0.0 0.4 0.2 0.0 1.5 0.0 0.0 0.6 0.0 0.4 4.1 0.6 1.8 4.7 1.1 0.0 0.0 6.6 119.9 0.0 0.0 35.3 0.5 0.1 0.0 31.3 0.2 0.0 0.0 5.1 0.6 0.1 1.6 0.0 0.0 0.0 0.3 23.9 0.0 0.3 ENPP7 "alk-SMase, NPP7" ENSG00000182156 "Ectonucleotide pyrophosphatase/phosphodiesterase 7" Q6UWV6 17 79730943-79742219 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 104.6" "Group enriched" "Detected in some" 7 "Hepatocytes: 9.1;Proximal enterocytes: 22.7;Proximal tubular cells: 9.7" "Cancer enriched" "Detected in some" 6 "liver cancer: 6.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Hep G2: 1.2;Karpas-707: 2.1;U-266/70: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA024603 Approved "Intracellular and membrane" NA NA 450000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA024603: AB_1848174" "unprognostic (4.00e-2)" "unprognostic (1.16e-2)" "unprognostic (6.49e-2)" "unprognostic (4.83e-2)" "unprognostic (1.55e-1)" "unprognostic (2.65e-2)" "unprognostic (1.24e-1)" "unprognostic (1.01e-1)" "unprognostic (8.45e-4)" "unprognostic (4.83e-2)" "unprognostic (1.18e-2)" "unprognostic (1.52e-2)" "unprognostic (5.21e-2)" "unprognostic (1.25e-1)" "unprognostic (1.80e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 11.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.6 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 9.1 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.7 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5 (inactive)" O75356 14 73958010-74019399 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 107.2;kidney: 95.2;liver: 263.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 209.3;Hepatocytes: 134.8;Intestinal goblet cells: 77.1;Proximal enterocytes: 87.0" "Group enriched" "Detected in all" 5 "liver cancer: 18.2;prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.3;eosinophil: 9.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 18.3" "Cell line enhanced" "Detected in all" "RT4: 57.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced "Secreted to blood" NA NA 5900000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" 8.2 7.7 5.0 11.4 7.3 8.0 12.4 7.1 6.7 7.3 7.1 94.6 72.1 6.3 7.7 11.3 5.7 12.1 7.7 5.1 6.3 95.2 263.7 6.5 5.5 7.6 7.3 6.7 4.9 7.7 5.0 5.6 7.8 37.7 107.2 9.4 10.7 4.4 15.0 8.1 68.4 9.7 6.5 6.0 42.3 8.6 7.3 4.6 6.1 9.1 5.6 16.9 7.2 9.0 9.5 7.8 8.2 15.1 16.5 15.5 9.4 9.6 7.9 6.4 7.1 5.6 10.9 10.6 4.7 12.8 6.0 10.8 8.5 14.1 7.2 8.8 4.0 7.9 5.7 30.9 15.5 4.7 8.8 12.9 14.0 8.7 18.2 8.8 13.1 17.1 8.8 15.4 9.7 13.6 5.4 5.6 2.5 8.5 15.7 6.0 8.0 5.2 11.4 57.1 5.8 6.0 16.6 12.9 9.2 6.4 18.7 4.1 10.8 12.6 12.7 7.5 7.2 10.1 16.9 8.3 8.0 8.8 11.5 18.3 1.2 9.4 2.5 2.3 1.3 1.4 1.3 1.8 1.7 1.5 2.1 2.1 0.1 0.5 1.4 0.9 1.6 1.3 5.0 7.3 7.1 6.7 5.1 6.3 7.6 7.3 7.8 6.5 7.3 9.0 8.0 16.0 6.7 8.1 4.9 3.7 6.2 8.9 5.2 6.6 15.0 7.9 5.2 10.0 11.3 7.3 4.2 8.2 4.3 209.3 25.4 6.9 19.5 10.0 13.6 7.0 16.2 36.6 5.9 12.9 6.7 7.9 23.0 25.8 1.3 9.6 9.7 134.8 6.2 10.1 8.2 77.1 14.2 9.7 1.9 12.7 2.8 5.2 5.4 11.2 5.4 4.9 8.2 2.0 11.3 9.1 58.4 5.7 3.6 28.5 87.0 63.1 6.4 12.2 13.1 6.0 5.9 27.2 19.1 8.5 3.4 3.3 4.9 10.3 60.9 39.0 ENTPD8 "NTPDase-8, UNQ2492" ENSG00000188833 "Ectonucleoside triphosphate diphosphohydrolase 8" Q5MY95 9 137434364-137441816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 27.6;liver: 14.5" "Group enriched" "Detected in some" 5 "Distal enterocytes: 194.5;Intestinal goblet cells: 181.0;Paneth cells: 174.3;Proximal enterocytes: 167.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.0;OE19: 1.7;RPMI-8226: 5.3;T-47d: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021509 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA021509: AB_1848185" "unprognostic (3.85e-2)" "unprognostic (8.33e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (6.46e-3)" "unprognostic (8.70e-2)" "unprognostic (3.87e-2)" "unprognostic (8.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.34e-2)" "unprognostic (1.08e-5)" "prognostic favorable (7.17e-4)" "unprognostic (2.17e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" 0.0 0.0 0.0 1.4 0.0 0.4 0.4 0.2 0.2 0.6 0.0 21.3 27.6 0.1 0.0 0.3 0.7 3.7 0.0 0.0 0.0 3.1 14.5 0.1 0.1 0.2 0.1 0.1 3.1 0.1 5.1 0.1 0.0 0.4 11.2 0.0 6.3 0.2 0.0 0.1 27.2 0.1 0.0 0.2 8.9 0.5 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.1 5.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 1.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 1.7 0.2 0.0 0.0 5.3 0.7 0.0 0.2 0.5 0.1 0.0 0.1 0.4 2.8 0.1 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.0 1.7 1.5 0.4 11.5 0.3 20.2 0.0 0.0 0.1 194.5 0.0 1.3 0.0 3.0 0.4 0.1 3.6 0.0 0.0 7.5 0.2 0.1 31.6 4.7 0.0 0.1 0.4 10.1 0.1 0.0 0.0 181.0 8.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 174.3 0.0 0.2 0.6 167.3 5.9 1.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.3 0.3 0.1 15.6 1.7 EOGT "AER61, C3orf64, FLJ33770" ENSG00000163378 "EGF domain specific O-linked N-acetylglucosamine transferase" Q5NDL2 3 68975217-69013684 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Peritubular cells: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 86.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019460 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear membrane" Cytosol "HPA019460: AB_1844628" "unprognostic (2.62e-1)" "unprognostic (3.72e-1)" "unprognostic (1.07e-1)" "unprognostic (1.95e-2)" "unprognostic (8.96e-2)" "unprognostic (6.30e-2)" "unprognostic (2.18e-3)" "unprognostic (6.66e-2)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" "unprognostic (1.68e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (8.97e-5)" "unprognostic (7.41e-2)" "unprognostic (4.67e-1)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" 19.4 9.1 7.2 12.8 7.2 5.9 19.5 6.7 10.9 14.0 22.4 25.8 7.4 29.9 9.8 17.5 18.5 17.8 28.5 7.1 7.0 10.2 5.7 28.7 8.2 7.7 7.6 11.6 12.6 5.0 9.3 22.3 8.0 27.9 8.6 8.8 16.4 33.7 20.0 9.7 11.4 25.4 7.8 10.0 15.5 8.9 7.8 11.1 7.9 15.2 8.8 24.7 13.7 7.5 19.0 7.1 12.5 14.4 16.6 32.2 8.6 25.4 31.5 16.0 21.0 9.1 10.2 1.1 3.8 28.1 13.6 6.0 8.3 32.3 19.9 62.3 5.6 20.2 15.5 13.5 18.7 11.5 8.2 26.8 29.4 20.6 25.1 19.4 86.2 0.8 5.9 11.1 53.7 5.5 2.0 3.8 13.5 6.2 3.5 0.8 12.4 8.2 13.9 43.4 1.2 6.3 29.1 1.7 23.5 12.8 6.0 15.9 44.6 40.6 13.4 5.1 24.3 6.0 20.5 9.3 16.3 17.1 23.8 5.4 1.5 0.0 2.0 1.4 2.3 1.1 3.0 4.3 2.4 0.7 2.5 2.7 0.2 2.4 0.5 0.4 6.6 1.3 7.2 7.2 6.7 10.9 7.1 7.0 7.7 7.6 8.0 7.8 7.8 7.5 29.6 12.8 10.3 14.0 3.5 7.1 11.4 13.2 16.5 2.2 7.5 11.7 20.7 4.3 14.5 1.8 16.7 0.9 3.1 5.1 0.0 4.6 16.5 15.3 7.5 23.7 6.0 3.8 11.2 8.2 5.3 9.3 9.2 15.4 0.0 9.4 20.3 3.6 6.7 0.0 21.4 4.5 2.0 6.8 9.8 15.1 3.1 8.6 8.8 30.9 6.5 1.4 1.0 9.5 12.2 12.4 3.4 40.6 5.4 8.3 2.1 1.9 13.2 5.6 0.0 26.8 15.2 5.5 2.5 14.8 4.5 0.8 7.0 6.9 3.4 8.6 EPCAM "17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 806.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2317.0;Ductal cells: 999.6;Intestinal goblet cells: 1378.2;Paneth cells: 2437.0;Proximal enterocytes: 2681.1;Undifferentiated cells: 1607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 538.9;CACO-2: 680.9;CAPAN-2: 944.4;OE19: 911.8;RPTEC TERT1: 398.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" 4.4 12.2 3.1 77.0 4.0 10.2 99.7 1.5 3.1 116.2 1.0 806.0 726.5 33.0 238.9 10.8 114.3 71.1 0.6 3.3 9.2 223.1 3.1 74.7 0.9 2.8 3.2 1.2 125.4 219.5 86.9 1.7 3.4 60.5 751.0 0.6 119.8 52.8 0.1 8.8 769.6 22.2 2.6 1.4 172.4 21.7 10.4 6.4 286.8 0.1 2.8 30.9 4.2 2.6 538.9 5.4 0.4 1.2 0.0 0.0 321.3 0.2 0.0 0.6 0.0 680.9 944.4 0.1 141.5 1.0 0.4 247.3 4.6 62.2 2.0 0.1 56.3 0.3 2.5 261.6 0.1 0.3 0.4 0.0 17.6 0.0 0.0 0.0 0.8 0.0 160.9 0.0 0.3 269.7 0.5 24.0 164.3 911.8 31.4 0.3 0.0 136.9 398.6 231.3 354.0 3.2 4.3 187.7 0.6 132.7 158.3 1.0 0.7 0.3 6.3 2.0 1.1 39.2 0.6 0.8 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 4.0 1.5 3.1 3.3 9.2 2.8 3.2 3.4 2.6 10.4 2.6 3.7 310.9 148.1 1.3 7.0 9.3 227.6 127.4 14.2 0.5 184.7 112.9 2.0 243.1 222.8 448.8 0.0 16.4 2.3 2317.0 76.3 999.6 8.6 434.7 35.3 5.8 498.1 23.1 1.1 402.8 6.5 6.3 150.3 445.3 32.5 11.8 1.4 0.6 2.9 0.0 0.4 1378.2 486.2 0.0 5.2 5.6 20.5 5.6 35.6 0.0 11.5 15.7 0.0 0.5 1.2 617.5 2437.0 18.8 1.8 257.9 2681.1 195.9 219.0 0.7 13.1 0.5 13.7 83.5 130.3 33.3 10.4 6.0 9.4 70.3 1607.7 230.7 EPDR1 "EPDR, MERP-1, MERP1, UCC1" ENSG00000086289 "Ependymin related 1" Q9UM22 7 37683843-37951936 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 122.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 95.5;Peritubular cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-937: 122.2;WM-115: 114.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026298, HPA072321" Enhanced "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "CAB026298: AB_425991, HPA072321: " "unprognostic (1.99e-2)" "unprognostic (9.30e-2)" "unprognostic (4.44e-3)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (4.85e-2)" "prognostic unfavorable (6.97e-4)" "unprognostic (2.53e-2)" "unprognostic (2.75e-1)" "unprognostic (3.13e-1)" "unprognostic (7.23e-2)" "unprognostic (1.85e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (4.13e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.00e-4)" 23.1 40.3 46.3 4.2 41.4 4.5 11.3 38.4 82.3 38.5 27.3 10.5 13.4 41.7 13.6 8.4 28.1 10.1 27.4 45.4 67.5 16.4 10.9 27.1 4.9 81.9 50.4 34.0 9.4 8.0 9.4 4.9 83.2 34.5 8.4 14.3 13.8 41.0 122.9 3.2 13.2 29.9 50.9 17.2 5.7 13.0 58.5 11.4 31.0 72.1 3.0 8.8 17.0 38.9 0.2 77.9 6.4 0.1 57.9 20.8 0.1 5.9 0.0 3.0 9.1 7.7 5.1 0.0 84.2 86.0 88.7 0.2 1.8 0.7 0.0 0.1 9.8 34.9 10.2 49.5 0.5 29.1 0.2 35.1 0.0 21.1 0.4 20.0 0.0 34.3 0.0 25.2 51.6 5.1 11.3 25.1 24.0 0.0 11.6 35.2 22.3 30.6 47.3 19.3 8.4 29.3 0.0 3.8 28.2 15.3 0.1 20.4 0.0 16.6 27.8 46.6 36.7 33.8 15.4 0.5 75.5 122.2 114.7 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.4 0.0 0.8 0.0 2.2 0.0 0.1 46.3 41.4 38.4 82.3 45.4 67.5 81.9 50.4 83.2 50.9 58.5 38.9 6.4 32.1 46.2 12.7 1.4 1.3 7.8 3.5 1.2 5.7 1.1 10.5 20.7 7.2 12.7 1.8 0.0 0.5 6.8 5.1 17.6 10.0 0.3 5.5 31.8 2.4 3.6 25.6 36.9 8.0 0.2 15.0 1.5 5.9 2.5 95.5 7.5 10.7 3.1 11.8 39.3 5.1 0.0 1.6 2.0 2.1 28.3 3.1 28.4 14.0 14.2 13.3 2.1 24.6 13.0 19.7 6.9 98.9 0.2 14.6 19.3 14.8 5.7 7.2 6.6 46.4 23.9 0.3 1.8 0.5 0.3 0.1 1.2 28.7 6.4 2.6 EPG5 "hEPG5, KIAA1632" ENSG00000152223 "Ectopic P-granules autophagy protein 5 homolog" Q9HCE0 18 45847609-45967329 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 53.1;Oligodendrocytes: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "LHCN-M2: 55.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031689 Uncertain Approved "Nuclear speckles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "HPA031689: AB_10609997" "unprognostic (3.43e-1)" "unprognostic (1.20e-1)" "unprognostic (8.11e-2)" "unprognostic (6.84e-2)" "unprognostic (2.20e-2)" "unprognostic (4.59e-2)" "unprognostic (5.58e-2)" "unprognostic (1.02e-1)" "unprognostic (4.66e-1)" "unprognostic (4.87e-1)" "unprognostic (1.15e-2)" "unprognostic (7.50e-2)" "prognostic favorable (4.04e-5)" "unprognostic (5.71e-2)" "unprognostic (1.35e-1)" "unprognostic (4.05e-1)" "unprognostic (1.18e-1)" 6.6 6.8 5.8 4.4 6.0 13.8 6.8 6.3 6.2 7.1 5.1 5.8 3.2 6.1 5.8 7.1 6.0 3.2 8.4 6.2 5.3 6.6 6.0 8.8 5.7 5.1 8.1 8.9 6.3 6.9 7.6 4.5 5.3 5.9 4.0 8.6 6.0 3.7 8.6 10.1 6.0 4.1 4.5 9.5 5.6 4.8 5.8 8.4 9.3 6.7 5.9 5.4 6.6 6.3 5.3 4.1 4.1 3.0 13.8 16.6 4.1 33.2 13.7 18.7 19.4 1.2 3.9 5.4 2.0 25.0 22.5 4.9 5.5 6.6 23.7 4.5 2.3 4.2 4.7 4.2 13.1 7.2 10.4 11.2 6.0 20.6 14.0 16.5 9.4 4.7 3.7 2.8 55.8 3.7 3.2 6.9 2.0 1.9 2.5 3.0 5.1 3.8 8.8 7.3 4.4 3.4 5.9 2.4 7.0 5.8 3.4 5.1 23.0 23.2 4.9 3.4 9.2 5.7 4.3 3.0 9.9 6.2 7.7 0.4 0.7 0.7 1.5 0.7 1.4 0.4 0.9 0.8 0.5 0.6 0.7 0.9 0.8 0.4 0.6 0.6 0.5 0.3 5.8 6.0 6.3 6.2 6.2 5.3 5.1 8.1 5.3 4.5 5.8 6.3 8.8 19.2 10.5 24.5 9.0 10.3 4.6 6.8 8.0 16.7 11.9 8.3 17.1 10.0 7.4 11.0 25.0 7.6 15.7 5.8 1.9 6.5 4.6 9.0 9.8 9.3 8.3 11.4 53.1 3.6 4.4 7.8 6.1 16.9 7.0 14.4 13.6 10.3 12.2 13.5 46.5 6.9 6.1 16.0 6.2 3.0 12.5 11.5 14.2 40.3 16.6 6.5 27.8 40.2 51.4 7.8 6.5 11.7 10.0 9.1 6.2 8.3 10.5 17.4 13.1 9.8 6.7 8.4 7.1 5.9 13.2 9.0 15.4 9.8 6.5 9.4 EPGN "ALGV3072, EPG, PRO9904" ENSG00000182585 "Epithelial mitogen" Q6UW88 4 74308470-74316789 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 49.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.0;Basal prostatic cells: 7.3;Basal squamous epithelial cells: 25.6;Urothelial cells: 5.1" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTCEpi: 157.9;U-2197: 74.8" "Not detected" "Not detected" HPA014420 Approved Nucleoplasm,Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" Vesicles "HPA014420: AB_10601551" "unprognostic (7.51e-2)" "unprognostic (8.08e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (1.77e-1)" "unprognostic (2.38e-4)" "unprognostic (2.20e-1)" "unprognostic (2.01e-1)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (4.06e-4)" "unprognostic (3.84e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (2.40e-4)" 1.6 0.1 0.2 1.6 0.1 0.3 1.4 0.4 0.6 5.2 0.1 0.1 0.1 0.0 1.1 49.0 1.5 0.1 0.8 0.2 0.1 0.1 0.2 0.5 0.1 0.2 0.3 0.1 0.1 2.2 0.1 0.5 0.1 0.2 0.0 0.2 3.6 3.1 0.1 3.5 0.1 0.0 0.1 0.3 0.0 1.1 0.1 0.9 0.0 0.0 3.4 1.3 9.6 0.4 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.2 0.0 0.0 0.4 0.0 0.8 0.0 0.1 1.8 0.2 3.6 0.0 2.8 0.0 0.0 0.0 0.5 20.2 0.0 0.2 0.0 0.7 0.0 157.9 2.9 11.7 0.0 0.0 0.1 0.6 0.0 0.0 1.0 0.0 0.0 0.3 0.0 3.6 0.4 0.0 0.0 0.3 0.3 0.1 0.0 8.3 3.3 0.0 0.0 0.5 0.0 0.2 0.4 0.1 74.8 0.2 0.0 0.0 0.1 0.7 0.1 0.2 0.7 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.3 0.3 0.1 0.7 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.6 0.2 0.1 0.2 0.3 0.1 0.1 0.1 0.4 0.0 0.0 1.5 0.0 0.0 6.0 7.3 0.9 25.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 3.1 0.0 0.1 1.8 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 3.0 1.6 0.1 0.2 0.0 0.0 5.1 EPHA10 "FLJ16103, FLJ33655" ENSG00000183317 "EPH receptor A10" Q5JZY3 1 37713880-37765133 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.6;intestine: 13.4;testis: 13.4" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 91.8;Early spermatids: 59.1;Late spermatids: 183.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.9;HDLM-2: 19.4;SCLC-21H: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027497 Uncertain "Intracellular and membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA027497: AB_10601158" "unprognostic (9.27e-2)" "unprognostic (1.21e-1)" "unprognostic (2.94e-2)" "unprognostic (1.24e-6)" "unprognostic (1.06e-1)" "unprognostic (1.11e-2)" "unprognostic (5.39e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-2)" "unprognostic (1.40e-1)" "unprognostic (7.06e-3)" "unprognostic (1.50e-1)" "unprognostic (8.81e-5)" "unprognostic (2.55e-2)" "unprognostic (2.97e-2)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" 0.0 0.4 4.2 0.9 4.4 0.3 0.9 0.0 7.6 0.2 0.0 13.4 3.5 0.1 3.9 0.4 0.9 1.0 0.1 4.3 2.1 0.2 0.0 0.1 0.2 1.9 0.4 0.0 2.6 1.3 6.7 0.0 0.7 0.6 6.3 3.1 1.4 0.2 0.0 0.2 6.7 0.4 0.0 0.1 3.1 13.4 4.1 0.1 0.4 0.0 0.1 0.2 0.2 1.8 1.5 1.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 1.6 2.7 0.0 0.4 0.0 0.2 0.1 0.1 0.0 0.0 19.4 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.7 0.0 1.0 0.0 0.1 0.7 2.0 0.6 0.0 0.0 0.4 0.3 1.7 8.6 0.4 1.1 0.0 0.0 0.2 2.8 0.1 0.0 0.0 0.9 0.1 0.0 1.7 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.2 4.4 0.0 7.6 4.3 2.1 1.9 0.4 0.7 0.0 4.1 1.8 0.0 0.0 0.5 0.3 0.2 0.1 0.0 0.0 0.0 5.6 1.3 0.9 1.5 0.0 0.1 0.0 91.8 0.0 0.0 23.8 0.0 0.4 59.1 0.0 0.0 0.1 18.7 0.0 24.5 2.5 0.0 0.3 1.5 0.1 0.0 0.1 0.0 0.0 0.0 11.8 15.8 10.5 0.0 0.0 0.0 183.7 1.8 0.1 0.0 1.0 0.0 0.4 0.0 2.5 2.2 2.3 21.1 0.4 0.0 0.2 7.8 0.0 0.0 3.1 0.0 0.0 0.1 18.2 2.6 0.0 0.0 0.0 0.1 0.0 11.0 0.2 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EPHA4 "Hek8, TYRO1" ENSG00000116106 "EPH receptor A4" P54764 2 221418027-221574202 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 39.7" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 317.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 14.9" "Group enriched" "Detected in many" 6 "cerebral cortex: 23.8;hippocampal formation: 20.9" "Group enriched" "Detected in many" 9 "basophil: 1.6;gdT-cell: 1.7;MAIT T-cell: 1.7;memory B-cell: 1.3;memory CD4 T-cell: 2.5;memory CD8 T-cell: 1.7;naive B-cell: 1.2;naive CD4 T-cell: 1.0;NK-cell: 3.5;T-reg: 1.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 77.0;ASC diff: 33.9;CACO-2: 59.3;U-2197: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB028368 Enhanced NA NA 9300000 "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB028368: AB_2099353" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (2.28e-1)" "unprognostic (2.46e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (7.05e-4)" "unprognostic (1.80e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (1.12e-1)" "unprognostic (2.85e-2)" "prognostic favorable (5.67e-4)" "unprognostic (3.12e-2)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (8.66e-2)" 7.8 1.6 0.0 1.9 3.9 3.7 3.9 0.0 23.8 4.5 39.7 4.6 1.0 6.4 2.8 4.8 4.9 3.1 17.4 20.9 0.0 4.8 0.8 3.6 2.7 0.0 1.5 11.1 1.1 1.9 0.6 1.6 0.0 5.3 4.5 4.2 2.6 6.1 2.7 12.9 2.8 8.0 0.0 3.4 2.3 11.7 3.7 3.8 9.5 4.0 3.2 3.6 3.5 0.0 2.6 2.4 77.0 0.0 33.9 20.9 0.1 18.2 8.3 16.9 6.2 59.3 0.9 0.0 0.1 26.7 0.0 7.0 12.3 0.1 7.0 9.7 6.4 0.0 0.9 0.0 0.9 0.0 1.4 8.5 4.2 5.3 0.1 10.3 14.9 0.0 0.0 0.0 4.4 9.5 0.2 0.0 5.6 5.9 1.7 0.1 8.5 0.0 25.8 4.3 13.2 0.0 6.2 1.3 1.3 6.2 2.9 0.0 0.0 1.7 3.2 38.4 1.0 0.0 0.1 0.0 6.9 0.0 3.6 1.6 0.0 0.0 1.7 0.0 1.7 1.3 2.5 1.7 0.0 1.2 1.0 0.2 0.1 3.5 0.0 0.1 1.2 0.4 0.0 3.9 0.0 23.8 20.9 0.0 0.0 1.5 0.0 0.0 3.7 0.0 36.3 0.0 6.4 51.9 8.2 6.1 0.7 9.7 2.8 9.8 4.3 6.0 31.6 7.2 13.7 9.2 0.0 0.1 12.2 4.7 7.9 0.2 3.9 1.9 5.7 26.3 3.5 0.0 317.9 0.2 0.0 5.1 4.6 5.2 1.3 9.0 20.0 0.4 0.3 1.7 68.8 12.8 8.2 0.0 1.5 5.8 1.2 0.9 7.2 70.3 0.2 7.2 3.1 8.0 7.9 30.9 3.6 8.6 2.1 1.4 0.1 1.7 4.5 3.2 0.0 3.6 10.2 10.0 1.9 4.1 12.5 0.0 5.4 11.3 6.6 2.4 EPHA6 FLJ35246 ENSG00000080224 "EPH receptor A6" Q9UF33 3 96814581-97752460 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 24.2;ovary: 6.3;testis: 8.4" "Cell type enhanced" "Detected in some" "Astrocytes: 421.5;Early spermatids: 401.8;Excitatory neurons: 423.8;Inhibitory neurons: 879.2;Late spermatids: 208.7" "Cancer enhanced" "Detected in single" "prostate cancer: 0.7" "Region enhanced" "Detected in many" "cerebellum: 24.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HEK 293: 9.3;U-266/70: 28.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007397, HPA058047" Uncertain Enhanced Nucleoplasm NA NA "Cluster 6: Brain - Smell perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA007397: AB_2667821, HPA058047: AB_2683588" "unprognostic (9.87e-2)" "unprognostic (1.67e-2)" "unprognostic (3.42e-4)" "unprognostic (7.21e-5)" "unprognostic (8.51e-2)" "unprognostic (1.32e-1)" "unprognostic (1.82e-2)" "unprognostic (3.14e-1)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (1.71e-4)" "unprognostic (1.93e-3)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (7.14e-3)" 0.2 0.0 6.5 0.0 12.7 0.0 0.2 24.2 10.9 0.8 0.0 3.2 0.1 0.9 0.3 0.8 1.9 0.9 0.3 11.4 0.0 0.4 0.0 0.1 0.0 0.0 0.2 6.3 0.5 0.1 0.1 0.0 1.1 1.0 0.7 1.1 0.1 0.6 0.0 0.0 0.3 1.4 0.1 0.0 0.6 8.4 3.5 0.2 2.0 0.1 0.1 1.4 0.6 0.0 0.0 0.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 9.3 0.0 2.2 0.0 0.0 2.3 0.0 0.0 0.4 0.0 0.9 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 2.4 0.0 0.9 28.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 12.7 24.2 10.9 11.4 0.0 0.0 0.2 1.1 0.1 3.5 0.0 0.0 0.0 0.0 421.5 0.1 0.3 0.3 0.0 5.2 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 401.8 0.1 1.4 0.1 0.0 0.0 423.8 0.0 0.0 0.9 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 879.2 0.0 0.0 0.0 0.0 208.7 3.1 0.2 0.0 30.0 0.0 1.0 0.0 31.2 9.0 0.1 0.0 1.5 0.0 0.1 0.0 1.7 0.0 0.3 0.0 0.2 0.1 14.7 2.7 6.0 0.0 0.1 0.0 0.4 0.0 0.1 EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419687 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.6;parathyroid gland: 69.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 138.6;Inhibitory neurons: 172.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 12.0;HEK 293: 35.1;RH-30: 31.7;THP-1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010496 Approved "Intracellular and membrane" NA NA 660000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" 0.3 0.0 1.2 0.4 3.4 0.0 1.2 3.4 5.1 1.4 0.0 24.6 1.5 0.9 0.2 0.2 0.5 2.2 3.6 4.9 2.6 5.9 0.0 0.2 0.0 1.2 2.2 1.9 0.1 69.9 1.2 0.4 1.5 9.7 2.5 1.8 5.4 0.9 0.1 0.2 4.4 2.1 0.4 3.9 10.3 0.9 0.6 0.0 0.1 0.1 0.0 8.2 1.8 1.2 0.0 0.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 35.1 0.0 3.0 0.0 0.0 0.0 0.0 0.5 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.6 0.0 1.0 5.4 31.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 32.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.4 3.4 5.1 4.9 2.6 1.2 2.2 1.5 0.4 0.6 1.2 0.2 0.0 0.0 4.2 0.0 0.4 0.4 0.0 0.6 18.5 3.1 1.8 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 13.1 1.3 1.4 1.8 0.0 0.0 138.6 0.0 0.0 5.9 0.0 3.8 0.0 3.7 0.0 0.0 0.1 11.8 172.0 0.0 0.0 0.0 0.4 3.3 0.9 0.1 0.0 11.2 0.0 0.4 0.0 4.5 8.3 0.1 0.0 0.0 0.0 0.4 0.0 11.8 0.0 1.0 0.0 0.2 0.5 0.2 1.1 0.2 1.0 0.0 0.2 0.9 0.0 0.1 EPHA8 "EEK, Hek3" ENSG00000070886 "EPH receptor A8" P29322 1 22563489-22603595 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 27.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.2;Cone photoreceptor cells: 2.1;Early spermatids: 2.8;Horizontal cells: 3.3;Late spermatids: 5.8;Rod photoreceptor cells: 8.8" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "SCLC-21H: 59.6" "Region enhanced" "Detected in many" "cerebellum: 13.0" "Region enriched" "Detected in many" 4 "cerebellum: 11.7" "CAB009660, HPA031433" Uncertain "Intracellular and membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "CAB009660: AB_2099696, HPA031433: AB_10601371" "unprognostic (8.58e-2)" "unprognostic (8.59e-2)" "unprognostic (3.72e-1)" "unprognostic (1.15e-2)" "unprognostic (4.69e-4)" "unprognostic (3.58e-1)" "unprognostic (7.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.75e-2)" "unprognostic (9.80e-2)" "unprognostic (2.10e-1)" "unprognostic (9.84e-14)" "unprognostic (2.14e-3)" "unprognostic (1.69e-1)" "unprognostic (2.76e-1)" "unprognostic (8.68e-2)" 0.0 3.5 2.7 0.0 2.3 0.0 0.0 1.5 2.3 0.0 27.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 0.0 0.0 0.0 0.0 1.9 3.1 0.0 3.3 0.0 1.5 0.0 2.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.0 2.3 4.6 0.0 2.2 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.6 4.8 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.3 1.5 2.3 4.9 5.3 1.9 3.1 2.0 2.3 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.1 0.0 1.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 8.8 0.0 0.0 0.1 1.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3" "Cell type enhanced" "Detected in many" "Ductal cells: 45.1;Enteroendocrine cells: 48.7;Intestinal goblet cells: 61.1;Oligodendrocytes: 76.3;Pancreatic endocrine cells: 63.7;Undifferentiated cells: 97.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 86.5;HUVEC TERT2: 74.2;TIME: 79.2;U-251 MG: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" No No 380000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.1 1.6 2.1 9.2 3.7 0.5 1.6 4.1 4.2 2.5 0.0 22.6 21.0 1.8 1.9 0.6 4.4 3.7 3.3 2.2 4.3 3.8 0.4 1.8 2.9 5.7 4.5 10.6 3.9 6.1 2.9 4.0 4.8 1.9 23.3 2.9 1.5 3.0 0.2 0.9 21.8 3.3 5.0 2.4 1.7 1.8 5.4 1.2 7.3 0.3 1.7 4.4 1.0 8.2 43.4 17.2 17.2 27.7 1.6 1.5 0.0 10.0 0.5 27.3 5.7 6.3 16.6 0.6 20.2 4.0 86.5 39.6 10.8 52.8 7.7 0.1 4.1 0.0 1.9 0.1 16.5 0.0 4.3 5.3 17.5 48.7 0.3 25.4 74.2 2.4 1.8 0.1 5.7 6.4 1.1 0.3 4.0 49.0 11.2 5.3 18.0 0.8 14.7 4.0 18.0 19.3 17.4 0.7 0.2 1.5 1.1 0.5 79.2 11.5 29.6 29.4 69.5 0.0 0.2 0.1 21.8 0.9 0.5 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 3.7 4.1 4.2 2.2 4.3 5.7 4.5 4.8 5.0 5.4 8.2 0.4 3.2 0.0 5.5 0.3 0.8 1.7 20.5 0.0 15.4 0.1 0.1 1.3 7.2 8.6 0.0 0.0 0.5 0.1 24.3 0.0 45.1 2.6 1.0 0.8 1.2 48.7 0.0 34.1 8.0 2.8 5.0 1.1 2.4 0.0 0.5 0.4 0.4 9.6 6.7 32.3 61.1 6.1 7.6 1.4 0.8 0.9 7.2 0.0 21.5 0.7 18.4 0.0 5.5 76.3 63.7 12.6 0.7 0.3 2.3 5.5 0.2 1.7 1.8 0.0 0.6 2.1 0.5 3.5 0.0 0.4 1.1 0.3 0.2 97.2 1.1 EPHB4 "HTK, Tyro11" ENSG00000196411 "EPH receptor B4" P54760 7 100802565-100827523 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Angiogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 68.5;Hepatic stellate cells: 113.2;Syncytiotrophoblasts: 206.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.0;neutrophil: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB013537 Uncertain NA NA 1400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB013537: " "prognostic unfavorable (8.56e-4)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.33e-1)" "unprognostic (5.23e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.84e-1)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (9.51e-3)" "unprognostic (6.63e-2)" "unprognostic (3.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (8.84e-4)" 26.4 49.8 5.0 8.0 4.3 5.6 32.6 4.6 4.8 45.6 6.8 20.7 8.3 61.5 3.8 24.7 27.1 18.0 26.1 4.1 4.1 28.3 33.3 28.2 5.8 5.5 5.1 36.0 26.8 10.1 6.3 35.5 5.3 28.9 10.2 0.3 24.2 22.4 7.7 35.8 17.5 22.2 5.1 47.9 21.4 12.3 6.3 3.1 17.6 13.3 4.9 17.3 28.1 4.8 37.7 33.1 32.5 94.2 20.4 13.0 94.7 14.1 31.2 22.3 29.0 27.4 28.3 4.8 63.6 15.3 31.3 38.2 14.3 38.3 11.9 6.2 25.6 1.3 19.0 43.2 11.8 0.7 0.9 15.3 56.7 14.2 33.1 24.8 84.0 1.5 71.9 1.8 18.4 66.4 0.7 15.0 54.7 56.3 47.5 51.4 15.6 8.9 28.6 19.9 0.2 27.4 22.0 10.4 22.1 45.1 26.1 6.7 71.3 27.6 42.6 51.3 21.4 0.2 0.8 1.7 4.0 12.0 51.2 0.0 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 4.3 0.0 0.1 0.1 0.0 0.7 5.0 4.3 4.6 4.8 4.1 4.1 5.5 5.1 5.3 5.1 6.3 4.8 47.1 9.6 12.6 1.6 1.9 20.5 10.3 13.9 15.9 0.1 22.0 19.7 5.7 7.2 8.5 5.5 0.0 68.5 1.1 9.1 0.0 12.3 28.5 4.8 21.8 51.2 3.0 10.8 0.3 6.6 11.2 6.5 12.8 8.0 1.3 10.7 113.2 22.4 9.0 0.0 0.2 17.4 8.2 4.1 3.4 9.9 8.1 1.3 3.6 1.9 1.5 1.7 0.0 0.0 1.0 20.6 7.6 4.1 1.4 13.3 1.3 4.0 4.2 0.2 6.6 5.7 6.3 1.4 10.2 12.1 17.8 206.5 1.2 2.9 19.9 8.0 EPHX2 ABHD20 ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490781-27545564 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 333.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 180.0;Hepatocytes: 131.5;Proximal enterocytes: 399.0;Proximal tubular cells: 259.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 35.0;naive CD4 T-cell: 106.7;naive CD8 T-cell: 50.4;T-reg: 29.6" "Lineage enriched" "Detected in many" 23 "T-cells: 106.7" "Cell line enhanced" "Detected in many" "JURKAT: 139.4;K-562: 51.6;OE19: 102.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Enhanced Enhanced Cytosol NA NA 1100000 "Cluster 32: T-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA023094: AB_1848214, HPA023660: AB_1848215" "unprognostic (1.30e-1)" "prognostic favorable (2.45e-4)" "unprognostic (2.99e-2)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (3.30e-3)" "unprognostic (1.26e-3)" "unprognostic (3.31e-3)" "unprognostic (1.46e-1)" "unprognostic (3.55e-2)" "unprognostic (4.14e-3)" "unprognostic (1.98e-1)" "prognostic favorable (1.98e-10)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (2.26e-1)" 19.3 74.0 14.5 9.1 15.0 1.9 30.1 14.4 14.1 21.0 42.2 61.4 112.8 17.7 27.2 38.6 41.6 9.4 29.1 13.2 15.3 166.3 333.2 11.2 17.2 16.1 17.3 38.0 64.5 54.8 35.8 8.5 15.9 64.6 57.6 21.5 36.5 27.2 16.2 43.4 128.4 15.4 15.8 10.8 23.4 9.0 15.8 65.9 22.6 13.8 20.8 19.7 23.4 15.7 15.3 10.1 6.3 8.1 0.4 0.0 4.8 1.3 0.9 0.7 0.2 8.0 10.1 0.1 5.9 4.1 3.2 10.7 1.1 2.6 0.5 0.0 4.7 22.5 1.1 24.8 3.4 0.1 4.5 8.6 10.7 0.1 1.1 2.5 0.5 139.4 51.6 0.2 0.0 4.7 14.9 0.5 10.1 102.4 17.2 0.1 0.1 0.4 8.7 2.2 5.1 16.0 12.1 14.2 15.0 4.6 21.8 4.2 0.2 0.0 3.8 1.8 0.1 12.5 10.1 0.2 0.4 0.1 0.1 0.1 0.1 0.0 7.8 0.0 11.3 4.5 35.0 12.7 0.1 2.5 106.7 50.4 0.2 4.6 0.1 0.2 29.6 20.0 14.5 15.0 14.4 14.1 13.2 15.3 16.1 17.3 15.9 15.8 15.8 15.7 6.3 6.4 17.0 16.3 6.1 11.9 18.6 10.1 29.6 34.1 17.2 18.4 23.7 20.0 9.7 27.6 79.2 22.8 1.0 82.7 180.0 8.8 7.5 6.9 4.8 9.4 23.4 3.8 3.0 6.4 2.5 12.1 15.8 1.5 5.7 17.4 17.5 131.5 2.2 33.7 7.2 63.4 2.0 4.6 1.2 4.8 29.8 3.6 5.4 2.8 2.6 91.5 3.1 7.5 5.1 3.1 83.7 18.8 4.5 20.5 399.0 259.3 24.1 52.4 0.0 11.5 10.2 1.3 13.9 39.2 18.3 8.2 11.9 78.5 101.3 10.8 EPHX3 "ABHD9, FLJ22408" ENSG00000105131 "Epoxide hydrolase 3" Q9H6B9 19 15226919-15233435 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 68.9;skin 1: 76.5;vagina: 36.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 15.5;Club cells: 19.3;Squamous epithelial cells: 30.7;Suprabasal keratinocytes: 43.3;Urothelial cells: 23.3" "Cancer enhanced" "Detected in many" "cervical cancer: 30.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 19 "dendritic cells: 1.3;monocytes: 2.4" "Cell line enhanced" "Detected in some" "EFO-21: 2.5;NTERA-2: 2.3;OE19: 8.4;SuSa: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA012842 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA012842: AB_10601648" "unprognostic (1.39e-1)" "unprognostic (1.16e-2)" "unprognostic (1.54e-2)" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "prognostic favorable (2.27e-5)" "unprognostic (8.83e-3)" "unprognostic (1.50e-1)" "unprognostic (3.90e-1)" "unprognostic (4.36e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.43e-1)" "unprognostic (3.68e-2)" "unprognostic (1.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.01e-2)" 0.5 0.3 0.8 0.2 0.8 0.2 1.5 0.6 0.9 14.7 0.7 0.2 0.2 0.4 0.3 68.9 1.7 1.3 0.5 0.7 0.9 3.3 0.3 1.7 0.1 0.9 0.8 0.7 0.2 3.0 1.8 0.4 0.8 1.5 0.2 0.2 7.6 0.9 0.4 76.5 0.3 0.4 0.8 2.6 0.8 2.1 0.9 1.7 0.4 0.1 26.7 8.6 36.6 0.8 0.1 0.2 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 2.5 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.3 2.3 8.4 0.3 0.0 0.0 0.0 0.0 0.5 1.0 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.0 0.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 1.3 0.0 0.2 0.8 0.8 0.6 0.9 0.7 0.9 0.9 0.8 0.8 0.8 0.9 0.8 0.2 0.0 1.1 0.0 0.2 7.0 2.6 15.5 0.0 0.4 0.9 0.6 0.5 5.7 19.3 5.5 0.0 1.6 0.0 0.1 1.9 0.5 0.2 0.7 0.4 0.6 0.0 0.0 0.1 0.0 3.4 0.6 0.0 1.7 0.0 0.4 1.1 0.0 0.6 0.0 0.1 0.1 2.0 3.2 1.4 0.0 0.0 1.5 0.0 0.0 0.6 2.5 0.0 0.0 0.1 0.6 0.0 0.0 0.0 2.6 0.2 0.0 3.3 0.0 0.0 0.8 2.5 4.6 2.1 30.7 43.3 2.6 0.2 0.2 0.1 23.3 EPM2A "LD, LDE" ENSG00000112425 "EPM2A glucan phosphatase, laforin" O95278 6 145382535-145736023 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease variant, Epilepsy, Glycogen storage disease, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.8;tongue: 79.5" "Cell type enhanced" "Detected in many" "Astrocytes: 66.9;Early spermatids: 33.0;Excitatory neurons: 30.4;Inhibitory neurons: 50.7;Oligodendrocyte precursor cells: 56.8;Oligodendrocytes: 60.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 23.2" "Low region specificity" "Detected in all" "HPA053643, HPA055468" Enhanced Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA053643: AB_2797247, HPA055468: AB_2797252" "unprognostic (2.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.34e-3)" "unprognostic (2.92e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.52e-4)" "unprognostic (2.28e-1)" "prognostic favorable (4.08e-7)" "unprognostic (4.12e-4)" "unprognostic (2.17e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" 5.8 6.0 11.4 1.5 11.7 1.8 3.2 11.9 17.8 3.1 7.3 17.2 3.2 6.0 4.3 9.3 4.4 3.6 24.4 11.6 12.6 8.5 5.7 3.0 3.3 11.9 11.5 5.7 2.4 5.2 3.8 1.5 11.1 6.1 2.9 12.1 3.1 8.8 76.8 2.1 3.8 6.3 10.3 2.1 5.3 3.0 11.5 4.8 3.9 79.5 2.6 9.8 2.7 13.3 1.3 2.1 3.4 6.6 8.6 2.3 1.6 3.1 3.8 2.9 3.5 1.7 1.7 23.2 2.7 3.8 3.5 1.8 1.3 1.6 2.6 9.3 1.9 3.6 2.5 2.7 4.8 12.7 2.4 2.0 7.0 1.7 0.7 3.8 2.0 5.0 1.8 5.4 3.8 3.1 8.4 3.2 3.9 3.2 1.9 4.8 3.1 6.7 2.5 1.8 6.3 6.4 5.5 3.3 7.8 3.1 1.9 7.3 4.6 2.9 1.1 2.7 2.6 4.1 4.6 8.6 2.6 2.8 4.8 0.0 0.0 0.0 0.1 0.5 0.4 0.4 0.4 0.3 0.3 0.4 0.4 0.9 0.1 1.9 0.1 0.3 0.0 0.3 11.4 11.7 11.9 17.8 11.6 12.6 11.9 11.5 11.1 10.3 11.5 13.3 3.9 6.4 1.5 66.9 4.4 0.9 1.0 0.8 0.6 8.4 3.5 2.2 27.8 2.8 2.2 1.8 6.2 1.0 1.9 0.2 11.7 1.0 33.0 1.9 3.6 2.2 1.2 4.4 30.4 2.3 0.7 2.3 1.1 1.4 2.5 6.0 1.4 6.6 2.3 30.3 50.7 1.5 2.0 3.3 1.4 19.8 3.1 3.1 7.2 15.9 1.7 7.9 2.1 56.8 60.1 1.2 1.7 2.2 1.7 1.5 0.5 7.1 2.2 6.3 0.0 6.2 2.4 4.9 1.6 0.8 0.4 0.4 1.8 5.1 1.2 0.3 EPO EP ENSG00000130427 Erythropoietin P01588 7 100720468-100723700 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Erythrocyte maturation" Hormone "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 47.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 2.9;Exocrine glandular cells: 4.2;Extravillous trophoblasts: 14.0;Hepatocytes: 19.5;Pancreatic endocrine cells: 3.7;Syncytiotrophoblasts: 2.9" "Group enriched" "Detected in many" 5 "liver cancer: 2.7;renal cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "BEWO: 1.6;Hep G2: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" CAB010336 Supported "Secreted to blood" NA NA 12300 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB010336: AB_2098408" "unprognostic (2.93e-1)" "unprognostic (1.57e-2)" "unprognostic (1.08e-3)" "unprognostic (7.30e-2)" "unprognostic (1.09e-1)" "unprognostic (1.78e-3)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.52e-2)" "unprognostic (5.16e-2)" "unprognostic (9.70e-2)" "unprognostic (2.44e-3)" "unprognostic (3.31e-1)" "prognostic unfavorable (2.18e-6)" "unprognostic (4.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (3.34e-1)" 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.3 2.9 0.1 0.1 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.1 0.4 3.1 47.2 0.1 0.0 0.2 0.1 0.2 8.3 0.0 0.0 0.0 0.2 0.5 0.0 0.2 1.4 0.5 0.0 0.4 0.0 0.2 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.1 0.4 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 4.2 14.0 0.0 0.0 0.0 0.0 0.1 1.4 19.5 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 2.9 0.0 0.0 0.0 0.0 EPPIN "CT71, dJ461P17.2, EPPIN1, EPPIN2, EPPIN3, SPINLW1, WAP7, WFDC7" ENSG00000101448 "Epididymal peptidase inhibitor" O95925 20 45540626-45547752 "Predicted intracellular proteins, Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 83 "epididymis: 327.9;testis: 84.2" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 30.0;Granulosa cells: 13.6;Late spermatids: 29.2;Respiratory ciliated cells: 32.5;Sertoli cells: 13.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 1.8;U-87 MG: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA067335 Supported "Secreted in male reproductive system" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "HPA067335: " "unprognostic (1.17e-1)" "unprognostic (1.79e-1)" "unprognostic (3.08e-3)" "unprognostic (1.06e-2)" "unprognostic (3.75e-2)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (2.00e-2)" 0.3 0.3 0.7 0.3 1.1 2.4 0.2 1.9 2.4 0.5 0.1 0.4 0.7 0.7 327.9 0.3 1.3 0.2 0.1 0.9 0.0 0.2 2.3 0.4 0.5 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.6 0.2 0.4 1.2 0.3 0.8 0.2 0.8 0.7 0.1 0.0 0.4 0.2 84.2 0.4 0.0 0.7 0.0 0.2 0.1 0.0 2.0 0.8 0.1 0.3 0.3 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.5 0.3 0.6 0.3 0.0 0.6 0.3 0.1 0.0 0.0 0.5 0.1 0.3 0.5 0.4 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.6 1.8 0.0 0.4 0.2 0.7 0.8 0.1 0.2 0.7 0.2 0.5 0.1 0.2 0.3 0.5 0.3 0.1 0.3 0.3 0.4 0.4 0.7 0.7 0.6 0.9 0.5 0.6 0.8 0.3 2.6 0.2 0.8 0.8 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.7 1.1 1.9 2.4 0.9 0.0 0.1 0.0 0.6 0.0 0.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.1 0.4 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 30.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 29.2 4.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 32.5 0.0 13.1 0.0 0.4 5.6 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 EPPIN-WFDC6 SPINLW1-WFDC6 ENSG00000249139 "EPPIN-WFDC6 readthrough" O95925 20 45534196-45547662 "Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 78 "epididymis: 63.6;testis: 53.6" "Cell type enriched" "Detected in single" 6 "Respiratory ciliated cells: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA067335 Supported "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "HPA067335: " "unprognostic (1.46e-3)" "unprognostic (6.38e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 63.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EPS15 "AF-1P, MLLT5" ENSG00000085832 "Epidermal growth factor receptor pathway substrate 15" P42566 1 51354263-51519266 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Host-virus interaction, Protein transport, Transport" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 314.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008451, CAB010164, HPA061431" Approved Enhanced Vesicles,Cytosol "Intracellular and membrane" NA NA 65000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Vesicles, Cytosol" "CAB010164: AB_631445, HPA008451: AB_1848221, HPA061431: AB_2732662" "unprognostic (1.45e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (1.05e-2)" "unprognostic (7.72e-3)" "unprognostic (3.99e-1)" "unprognostic (1.42e-1)" "unprognostic (4.96e-3)" "unprognostic (9.26e-2)" "unprognostic (4.13e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.41e-1)" "unprognostic (5.36e-2)" "unprognostic (8.73e-3)" "unprognostic (2.13e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" 31.9 35.1 40.3 25.5 48.2 20.7 25.6 38.8 55.7 23.9 25.7 19.1 15.8 22.8 17.6 21.0 18.3 26.1 26.5 43.9 39.1 24.5 26.4 26.9 46.0 38.6 44.1 28.8 14.7 29.0 15.5 31.5 40.7 26.7 20.5 23.4 16.7 20.9 47.6 24.2 17.7 24.3 40.1 34.1 21.3 46.9 45.0 27.6 25.3 40.5 45.6 22.8 20.9 57.2 35.4 10.4 22.0 20.8 49.6 49.2 54.5 24.2 37.9 19.4 28.4 14.4 19.2 71.8 24.3 38.1 39.5 32.7 28.7 23.1 29.1 81.8 18.0 64.1 16.9 17.1 46.7 36.9 56.4 40.3 21.0 34.0 45.7 33.5 36.5 25.2 40.4 31.7 29.8 17.5 29.9 19.8 30.2 24.6 16.7 24.1 33.3 15.9 25.5 43.2 15.0 20.9 28.8 50.4 42.1 60.2 20.5 25.7 51.1 18.0 19.1 36.3 20.5 37.6 41.0 47.6 26.6 41.0 16.1 18.8 10.4 12.1 9.4 10.7 14.2 15.6 11.2 14.9 10.8 9.0 6.6 9.6 7.8 10.8 13.0 7.1 19.0 8.7 40.3 48.2 38.8 55.7 43.9 39.1 38.6 44.1 40.7 40.1 45.0 57.2 51.5 35.3 41.0 142.4 78.3 43.0 32.1 16.4 30.1 18.1 28.2 15.6 59.8 24.3 22.7 44.1 31.3 22.8 65.0 28.5 19.6 15.2 27.0 22.1 50.1 43.3 28.8 81.0 77.1 19.0 18.9 52.5 41.3 35.6 24.6 36.0 61.4 37.7 83.4 28.6 60.6 30.7 12.2 80.9 61.9 61.7 65.9 67.0 103.2 110.5 57.6 38.4 27.8 29.7 314.1 23.3 19.8 48.2 78.4 62.1 20.7 28.1 31.9 26.6 39.5 45.1 38.0 74.4 44.5 33.8 51.0 28.5 74.3 28.5 21.4 50.8 EPS8L1 "DRC3, FLJ20258, MGC23164, MGC4642" ENSG00000131037 "EPS8 like 1" Q8TE68 19 55072020-55087923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 124.3;skin 1: 59.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 104.1;Gastric mucus-secreting cells: 108.1;Paneth cells: 110.2;Syncytiotrophoblasts: 428.0;Urothelial cells: 189.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 17.6;BEWO: 58.8;SK-BR-3: 19.6;T-47d: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041851, HPA043545" Uncertain Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA041851: AB_2677706, HPA043545: AB_2678544" "unprognostic (1.91e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (7.18e-2)" "unprognostic (9.33e-2)" "unprognostic (2.54e-2)" "unprognostic (4.61e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.43e-2)" "unprognostic (5.84e-3)" "unprognostic (2.65e-2)" "unprognostic (3.85e-3)" "unprognostic (5.04e-3)" "unprognostic (3.02e-1)" "unprognostic (5.41e-3)" "unprognostic (2.63e-1)" 4.5 0.2 0.0 0.9 0.1 0.1 4.0 0.0 0.1 24.0 0.0 3.5 2.3 1.5 0.0 124.3 14.8 0.9 0.6 0.1 0.0 25.1 0.7 3.9 0.0 0.1 0.1 0.5 5.6 2.1 2.1 5.4 0.1 9.2 0.6 0.0 20.4 2.5 0.5 59.7 2.0 0.0 0.0 0.6 27.0 0.6 0.2 0.1 17.4 0.0 1.6 2.7 37.1 0.2 17.6 0.7 0.6 0.4 0.0 0.0 58.8 1.5 0.1 0.0 0.1 7.6 13.7 0.3 3.4 0.0 0.1 9.7 0.4 2.1 0.0 0.3 1.6 1.3 0.6 0.5 0.2 2.6 10.8 0.0 3.6 0.0 0.0 0.0 0.0 1.2 6.2 0.1 0.0 8.0 0.9 2.6 0.8 12.7 0.0 0.1 0.0 5.4 2.7 3.6 0.2 3.8 1.0 19.6 0.8 0.6 28.9 3.2 1.3 0.0 0.7 0.0 0.0 2.4 3.1 1.6 3.3 0.9 2.0 1.1 0.2 2.3 0.3 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.4 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.2 4.0 9.6 6.1 0.3 0.8 2.0 28.4 39.5 8.6 0.0 16.3 15.1 2.6 8.6 92.2 31.3 0.0 55.1 4.0 104.1 13.7 20.4 1.6 29.1 6.3 10.7 3.0 0.0 0.1 10.2 26.8 4.7 108.1 41.7 10.2 5.4 10.0 0.1 8.9 0.0 0.1 39.0 24.4 1.9 3.4 4.5 1.2 2.6 21.4 0.0 5.2 0.2 6.2 0.0 0.1 94.5 110.2 0.7 1.0 48.7 12.7 1.1 53.6 0.6 26.3 0.5 21.6 1.6 3.6 6.6 4.0 428.0 2.8 0.3 22.1 189.4 EPX "EPO, EPP, EPX-PEN" ENSG00000121053 "Eosinophil peroxidase" P11678 17 58192726-58205174 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "bone marrow: 33.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.5;Inhibitory neurons: 1.2;Microglial cells: 1.0;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "eosinophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Cell line enriched" "Detected in some" 68 "NB-4: 248.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA076792 Enhanced NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA076792: " "unprognostic (5.67e-2)" "unprognostic (1.73e-2)" "unprognostic (3.36e-2)" "unprognostic (3.30e-1)" "unprognostic (2.18e-1)" "unprognostic (1.34e-3)" "unprognostic (4.83e-1)" "unprognostic (3.16e-2)" "unprognostic (1.41e-1)" "unprognostic (1.52e-2)" "unprognostic (1.71e-4)" "unprognostic (7.38e-2)" "unprognostic (1.64e-1)" "unprognostic (2.02e-1)" "unprognostic (5.43e-2)" "unprognostic (1.02e-2)" "unprognostic (1.73e-1)" 0.0 0.1 0.0 0.2 0.2 33.7 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.3 0.0 0.1 0.5 0.1 0.0 0.0 1.3 0.1 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 3.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.2 248.2 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.2 2.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EPYC "DSPG3, Pg-Lb, SLRR3B" ENSG00000083782 Epiphycan Q99645 12 90963682-91005026 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "placenta: 6.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "breast cancer: 2.4;ovarian cancer: 7.7;pancreatic cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTERT-RPE1: 3.0" "Region enhanced" "Detected in single" "midbrain: 1.4" "Group enriched" "Detected in some" 5 "amygdala: 1.7;basal ganglia: 2.9;cerebral cortex: 2.7;hippocampal formation: 2.2" "HPA038212, HPA045455" Approved "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "HPA038212: AB_10672739, HPA045455: AB_2679330" "unprognostic (2.25e-1)" "unprognostic (2.08e-1)" "unprognostic (2.79e-1)" "unprognostic (4.28e-2)" "unprognostic (1.81e-2)" "unprognostic (4.07e-2)" "unprognostic (9.20e-2)" "unprognostic (3.23e-1)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.77e-2)" "unprognostic (6.44e-9)" "unprognostic (2.83e-2)" "unprognostic (3.08e-1)" "unprognostic (8.68e-2)" "unprognostic (1.20e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 6.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ERAP1 "A-LAP, ARTS-1, ERAAP1, KIAA0525, PILS-AP" ENSG00000164307 "Endoplasmic reticulum aminopeptidase 1" Q9NZ08 5 96760810-96808100 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 72.8;Inhibitory neurons: 79.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025095, HPA042317" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 30000000 "Cluster 34: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB025095: , HPA042317: AB_2677946" "unprognostic (2.33e-3)" "unprognostic (3.45e-1)" "unprognostic (1.84e-3)" "unprognostic (1.34e-1)" "unprognostic (1.86e-1)" "unprognostic (4.38e-1)" "unprognostic (1.88e-3)" "unprognostic (5.37e-2)" "unprognostic (1.45e-1)" "unprognostic (7.94e-2)" "unprognostic (4.52e-2)" "unprognostic (3.23e-1)" "unprognostic (7.09e-2)" "unprognostic (1.36e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (5.14e-2)" 51.5 15.8 3.7 37.0 4.3 27.9 25.5 3.1 5.6 21.8 2.3 37.9 63.4 22.0 14.4 13.2 25.5 23.7 17.1 3.4 5.2 16.4 32.9 31.2 38.2 8.4 5.7 20.7 13.7 19.1 8.2 47.0 7.0 18.6 43.7 12.4 19.3 22.0 20.9 36.5 55.1 21.7 5.0 30.8 33.7 9.1 6.6 63.7 17.5 19.6 36.8 27.3 11.7 6.8 25.9 14.1 21.3 20.0 114.7 111.5 61.4 18.3 59.6 44.0 76.2 17.6 91.1 75.3 37.6 36.0 61.8 25.7 17.8 38.1 27.3 139.8 7.5 24.7 10.0 13.9 130.9 12.0 44.1 46.8 16.2 50.6 15.5 64.3 61.1 48.8 12.9 74.7 26.7 11.6 113.2 12.4 10.6 3.1 10.4 82.4 28.8 38.4 32.8 39.0 7.8 5.5 29.6 19.8 28.6 14.6 17.1 57.0 48.8 37.4 12.6 6.2 31.1 26.9 53.9 57.8 40.2 40.2 22.5 28.8 15.2 18.0 22.6 12.3 20.2 14.8 19.2 19.1 10.5 18.3 22.3 18.1 15.8 23.1 20.6 16.7 13.9 13.7 3.7 4.3 3.1 5.6 3.4 5.2 8.4 5.7 7.0 5.0 6.6 6.8 11.1 9.6 16.3 34.0 15.3 25.0 14.2 19.2 8.6 13.6 6.6 3.9 10.6 10.0 16.9 9.2 2.1 9.6 21.1 24.4 0.0 12.4 27.0 12.7 15.0 16.3 10.3 14.1 72.8 15.5 11.9 18.4 16.3 19.8 15.2 13.9 16.8 28.0 17.6 3.3 79.3 23.9 4.1 29.9 16.1 7.3 9.9 22.9 7.2 24.4 32.5 9.0 20.6 32.6 70.1 12.3 14.1 16.1 32.3 13.5 47.3 6.9 23.1 7.6 0.0 10.3 22.6 1.4 1.8 9.8 11.1 9.2 21.8 5.7 27.3 14.9 ERAP2 "L-RAP, LRAP" ENSG00000164308 "Endoplasmic reticulum aminopeptidase 2" Q6P179 5 96875986-96919703 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 176.1;GAMG: 105.0;hTEC/SVTERT24-B: 83.2;MOLT-4: 98.8;TIME: 188.7" "Low region specificity" "Detected in all" "CAB025618, HPA034498, HPA064360" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 11000000 "Cluster 15: NK-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "CAB025618: , HPA034498: AB_2674191, HPA064360: " "unprognostic (4.62e-2)" "unprognostic (1.60e-1)" "unprognostic (4.98e-2)" "unprognostic (1.56e-1)" "unprognostic (3.14e-1)" "unprognostic (8.71e-2)" "unprognostic (2.60e-2)" "unprognostic (1.17e-2)" "unprognostic (5.03e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.01e-1)" "unprognostic (9.54e-3)" "unprognostic (6.59e-2)" "unprognostic (8.48e-2)" "unprognostic (4.65e-2)" "unprognostic (3.05e-1)" 7.8 7.1 3.0 31.5 3.0 7.5 11.9 2.3 4.3 12.2 3.0 16.2 32.6 8.4 17.5 10.5 7.0 11.0 7.5 2.9 2.5 11.3 14.5 18.1 46.4 4.3 3.3 8.5 2.9 3.7 3.6 11.0 3.5 10.3 6.2 2.3 6.6 7.0 8.9 10.1 21.5 3.4 2.7 36.7 19.0 1.7 3.8 49.9 5.6 9.9 29.7 14.7 6.8 3.5 2.1 2.4 1.7 0.9 1.9 3.8 0.6 8.1 13.8 7.3 12.3 7.9 176.1 12.2 35.1 11.5 105.0 2.9 0.9 65.4 5.8 4.3 7.9 0.6 3.0 8.5 2.7 43.2 19.2 25.3 12.8 83.2 0.6 1.2 4.9 27.4 0.2 25.8 20.8 1.4 98.8 22.5 0.2 0.0 3.7 45.7 16.2 29.3 55.2 15.4 3.5 0.2 1.1 0.9 16.5 0.4 6.5 1.7 188.7 3.9 1.1 10.0 24.6 26.2 23.2 4.2 50.8 5.8 0.9 23.0 12.1 15.4 24.8 27.5 31.3 28.5 34.6 30.6 19.8 17.7 37.4 28.9 4.2 45.4 28.5 6.9 34.6 27.6 3.0 3.0 2.3 4.3 2.9 2.5 4.3 3.3 3.5 2.7 3.8 3.5 46.7 32.1 20.0 11.8 62.6 5.7 11.2 24.4 12.0 1.5 3.1 5.8 4.4 8.6 15.9 44.1 0.0 11.5 35.6 48.1 0.0 5.3 0.3 7.0 10.6 34.1 1.8 15.8 2.5 25.5 17.0 23.4 17.3 7.4 7.0 33.4 31.4 16.3 12.3 0.0 2.1 23.3 8.2 29.4 14.2 0.7 10.5 33.0 7.2 21.5 19.4 6.5 20.6 7.1 4.9 22.1 27.6 7.9 56.0 4.3 52.4 6.2 15.7 2.8 0.0 12.2 12.2 0.9 0.8 10.0 3.0 6.7 54.2 9.3 34.2 10.5 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ERCC1 RAD10 ENSG00000012061 "ERCC excision repair 1, endonuclease non-catalytic subunit" P07992 19 45407334-45478828 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cataract" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004390, HPA029773, HPA050182, CAB072859, CAB072860" Supported Enhanced Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "CAB004390: AB_2278023, CAB072859: AB_2665703, CAB072860: AB_2665704, HPA029773: AB_10602129, HPA050182: AB_2681044" "unprognostic (1.54e-3)" "unprognostic (5.99e-2)" "unprognostic (1.58e-1)" "unprognostic (1.34e-1)" "unprognostic (1.41e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (9.69e-4)" "unprognostic (2.57e-1)" "unprognostic (5.80e-2)" "unprognostic (7.37e-2)" "unprognostic (1.93e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (9.00e-5)" "unprognostic (6.19e-2)" "unprognostic (1.96e-1)" "unprognostic (1.60e-1)" "unprognostic (1.43e-1)" 47.0 49.8 34.7 28.0 33.9 31.4 50.7 37.6 42.6 50.5 44.8 45.1 26.2 47.9 40.2 43.1 43.7 30.3 109.1 35.9 37.2 57.8 38.3 40.4 30.0 38.7 35.5 54.2 57.1 48.9 56.9 22.9 37.3 55.2 20.8 23.2 70.6 29.2 84.0 63.3 40.1 33.4 35.4 43.1 42.9 27.8 36.2 24.1 46.9 83.1 30.5 41.5 44.3 36.6 61.1 104.0 84.2 125.8 57.8 108.1 27.3 90.1 119.1 106.4 141.4 12.0 58.8 34.5 24.9 94.2 57.2 45.0 26.0 277.7 65.1 79.1 28.6 57.9 39.3 36.2 120.2 55.9 96.8 81.0 60.3 111.7 99.5 89.0 117.3 40.8 33.8 69.8 167.9 40.3 50.9 44.4 20.9 54.4 42.4 77.7 40.5 46.3 78.5 36.7 36.6 76.2 58.4 47.3 79.6 27.7 55.0 103.7 70.3 97.7 91.4 59.2 93.8 49.5 43.2 39.5 105.3 45.8 296.6 30.7 131.9 26.3 61.3 142.8 41.7 75.8 37.3 48.6 134.7 84.1 29.4 47.4 17.8 60.6 107.9 315.8 49.8 90.2 34.7 33.9 37.6 42.6 35.9 37.2 38.7 35.5 37.3 35.4 36.2 36.6 43.2 22.4 36.3 13.1 53.4 70.9 109.7 82.7 41.5 0.0 73.9 76.8 39.1 37.1 43.9 20.2 0.0 36.1 67.8 26.9 90.1 54.5 27.1 50.4 43.5 37.5 39.6 20.2 32.9 65.9 33.3 62.4 22.4 24.5 50.0 103.4 38.9 29.6 96.2 0.0 21.9 41.2 34.6 61.5 71.7 107.1 79.2 69.6 67.6 17.8 49.0 0.0 38.1 16.6 13.8 85.3 33.5 57.2 49.1 94.9 69.2 73.1 67.5 0.0 46.0 60.5 60.0 37.0 37.1 51.4 52.8 35.6 36.0 98.6 43.2 89.0 ERFE "C1QTNF15, CTRP15, FAM132B, FLJ37034" ENSG00000178752 Erythroferrone Q4G0M1 2 238158970-238168900 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 11.8;skeletal muscle: 14.9;testis: 12.8;thyroid gland: 24.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 6.3;Club cells: 2.5;Collecting duct cells: 1.8;Distal tubular cells: 3.9;Glandular and luminal cells: 1.8;granulocytes: 5.1;Respiratory ciliated cells: 2.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 20.3;RH-30: 25.6" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 277000 "Cluster 43: Testis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (1.66e-1)" "unprognostic (9.14e-2)" "unprognostic (3.64e-4)" "prognostic unfavorable (3.75e-4)" "unprognostic (2.84e-1)" "unprognostic (9.61e-4)" "unprognostic (4.68e-3)" "unprognostic (3.16e-3)" "unprognostic (9.63e-2)" "unprognostic (9.11e-2)" "unprognostic (1.31e-4)" "unprognostic (7.13e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (4.10e-3)" "unprognostic (4.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.33e-2)" 0.7 0.1 3.3 2.2 4.0 4.1 0.4 4.6 6.7 0.7 2.2 0.5 0.6 0.4 0.0 0.4 0.5 0.3 0.9 3.9 2.4 11.8 0.5 0.9 0.1 2.4 2.5 0.1 0.4 0.0 0.1 1.2 2.5 0.7 0.2 0.0 0.3 0.4 14.9 0.1 0.9 0.4 2.2 0.8 0.5 12.8 2.7 0.1 24.9 0.6 0.1 2.3 0.3 2.7 3.1 0.8 1.4 3.0 0.2 4.9 0.3 2.0 3.2 4.9 8.7 0.2 7.7 0.0 5.4 0.5 10.0 0.3 13.7 0.7 4.5 0.0 15.2 0.0 0.3 0.2 1.8 0.1 1.1 10.5 1.5 20.3 14.3 0.6 0.1 6.5 4.6 0.0 13.6 3.8 0.0 8.9 2.1 0.9 1.5 17.3 25.6 0.8 10.7 0.1 0.4 7.7 3.1 0.5 9.7 2.5 0.4 15.5 1.0 8.2 7.1 3.2 10.7 0.0 0.0 1.1 12.2 4.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.0 4.6 6.7 3.9 2.4 2.4 2.5 2.5 2.2 2.7 2.7 0.2 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 2.5 1.8 0.0 0.2 0.7 0.0 3.9 0.1 0.0 1.2 0.2 0.5 0.0 0.0 0.0 0.0 0.2 1.2 0.0 1.8 5.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 2.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 ERI3 "FLJ22943, PINT1, PRNPIP" ENSG00000117419 "ERI1 exoribonuclease family member 3" O43414 1 44221070-44355260 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 943.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027147, HPA029895" Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA027147: AB_1855725, HPA029895: AB_2673239" "unprognostic (1.31e-1)" "unprognostic (2.39e-2)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (5.94e-2)" "unprognostic (6.21e-2)" "prognostic unfavorable (2.04e-6)" "unprognostic (6.48e-2)" "unprognostic (2.67e-1)" "unprognostic (6.70e-3)" "unprognostic (5.30e-2)" "unprognostic (2.49e-1)" "unprognostic (1.49e-2)" "unprognostic (2.07e-1)" "unprognostic (7.47e-2)" "unprognostic (1.08e-1)" "unprognostic (2.07e-3)" 31.1 34.8 105.3 15.5 105.9 24.6 30.5 92.0 140.3 30.1 92.2 34.4 20.6 33.3 34.2 27.9 37.2 20.5 51.7 111.9 98.7 59.8 41.8 25.6 19.3 99.4 108.1 32.4 35.0 45.2 45.1 23.3 122.2 38.8 23.2 22.4 27.8 25.2 77.2 36.1 22.7 28.6 97.2 26.4 28.9 63.3 105.7 24.1 31.2 60.2 20.4 32.2 27.2 103.4 73.6 56.5 69.3 77.7 44.9 55.5 46.0 44.0 61.4 82.1 75.1 37.8 78.3 52.3 76.4 58.7 42.2 41.2 62.6 80.6 55.9 56.9 115.8 60.0 90.2 52.0 67.9 59.3 32.8 57.9 76.9 66.2 91.3 61.0 57.3 59.5 56.4 43.9 55.2 51.2 68.7 57.0 82.2 72.2 83.7 62.6 62.4 75.3 65.2 38.9 120.5 54.9 52.5 71.3 87.7 55.1 46.6 50.1 34.1 54.3 56.5 60.7 72.0 37.7 50.1 56.4 67.7 52.4 70.4 17.6 25.8 15.8 25.5 36.4 27.2 30.8 21.1 24.5 40.3 30.9 24.8 26.0 2.4 26.1 37.3 30.3 29.4 26.2 105.3 105.9 92.0 140.3 111.9 98.7 99.4 108.1 122.2 97.2 105.7 103.4 35.4 25.6 16.5 74.4 26.2 31.6 36.5 64.7 27.3 22.6 36.2 51.3 15.1 15.7 26.2 29.5 2.1 93.2 19.3 31.2 97.8 56.9 202.7 35.3 30.7 27.4 118.3 26.5 36.7 62.5 85.9 39.8 25.0 23.1 15.2 62.8 18.9 22.3 45.0 25.2 34.0 99.1 46.8 19.2 27.2 943.6 36.4 20.1 48.0 38.4 27.9 42.6 15.5 66.4 54.5 37.7 22.2 36.5 28.3 51.0 17.0 167.3 20.4 16.4 6.6 28.5 52.0 68.0 51.4 29.4 34.5 61.6 20.2 54.0 37.1 30.7 ERLEC1 "C2orf30, CL25084, ERLECTIN, XTP3-B, XTP3TPB" ENSG00000068912 "Endoplasmic reticulum lectin 1" Q96DZ1 2 53787044-53818819 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 394.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031501, HPA031502, HPA031503" Enhanced "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "HPA031501: AB_10600104, HPA031502: AB_10602174, HPA031503: AB_10670425" "unprognostic (1.27e-2)" "unprognostic (3.36e-3)" "unprognostic (3.17e-1)" "unprognostic (1.97e-3)" "unprognostic (1.08e-2)" "unprognostic (1.86e-1)" "unprognostic (3.27e-3)" "unprognostic (3.79e-1)" "unprognostic (1.29e-1)" "unprognostic (2.95e-2)" "unprognostic (1.82e-1)" "unprognostic (1.92e-1)" "unprognostic (4.71e-2)" "unprognostic (1.47e-1)" "unprognostic (8.13e-2)" "unprognostic (2.33e-2)" "unprognostic (3.92e-2)" 38.4 51.0 30.2 31.3 32.1 33.8 48.7 29.3 41.9 66.4 39.3 45.8 37.7 40.9 93.9 26.1 36.2 41.0 45.2 32.9 39.2 38.1 43.4 44.1 32.4 28.7 31.1 38.0 67.1 57.3 59.4 56.6 31.5 72.8 50.2 54.5 54.0 55.9 32.1 20.1 34.0 38.5 30.1 33.1 55.3 42.4 31.5 28.1 72.5 39.5 41.2 44.7 27.2 34.4 42.1 47.3 44.4 27.4 123.3 111.3 65.5 100.5 109.1 49.0 51.4 31.3 55.7 29.4 94.5 106.3 86.3 29.7 29.2 42.3 62.1 67.0 38.7 36.1 29.1 93.8 84.4 60.2 63.9 70.5 69.4 51.6 83.3 99.4 58.1 28.6 39.0 115.8 73.6 35.3 27.7 48.0 34.1 67.1 30.4 24.9 53.1 82.7 57.7 39.3 26.5 46.3 36.6 79.0 64.6 50.3 38.0 45.9 63.3 53.9 47.2 44.0 60.3 170.1 120.3 16.5 88.2 35.8 64.5 77.0 25.1 30.7 41.4 27.8 45.8 36.8 36.3 39.9 28.0 28.6 33.9 39.0 9.6 45.4 33.3 40.1 36.6 41.5 30.2 32.1 29.3 41.9 32.9 39.2 28.7 31.1 31.5 30.1 31.5 34.4 57.2 89.8 116.7 22.2 86.3 25.1 42.5 88.0 34.1 77.0 76.3 54.6 83.5 52.9 93.5 66.2 31.3 100.2 60.9 43.4 33.2 76.1 168.4 67.7 77.5 63.8 55.1 23.1 24.0 115.7 105.8 99.7 54.6 101.7 74.1 36.6 68.6 81.8 60.1 95.9 28.5 169.7 107.8 39.7 31.5 117.9 88.3 41.7 80.0 17.8 61.7 79.7 72.1 20.6 25.3 90.2 42.8 84.2 394.0 113.4 32.3 51.4 118.2 68.6 52.6 55.6 109.5 146.1 65.3 40.3 33.4 183.6 57.0 48.3 57.1 67.5 ERLIN1 "C10orf69, Erlin-1, KE04, SPFH1, SPG62" ENSG00000107566 "ER lipid raft associated 1" O75477 10 100150094-100186033 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 114.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 77.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011252 Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "HPA011252: AB_1853965" "unprognostic (3.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (6.98e-3)" "unprognostic (2.69e-1)" "unprognostic (1.70e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (7.63e-4)" "unprognostic (1.26e-1)" "unprognostic (9.68e-2)" "unprognostic (1.99e-3)" "unprognostic (9.09e-2)" "unprognostic (1.32e-3)" "unprognostic (6.10e-3)" "unprognostic (1.76e-1)" "unprognostic (2.97e-1)" "unprognostic (1.93e-1)" 29.4 14.2 8.6 21.4 10.5 76.2 21.4 9.5 10.1 27.5 10.3 37.0 40.4 21.8 17.6 32.8 31.6 16.3 11.0 9.6 9.4 27.2 114.1 19.1 14.5 8.6 8.2 30.4 19.2 19.4 5.4 42.2 9.0 17.7 38.2 10.8 15.1 16.4 8.6 22.5 30.2 22.4 8.8 16.6 36.8 28.0 9.0 15.6 26.2 13.6 21.2 28.6 19.1 9.7 97.4 95.3 46.9 86.3 113.5 107.9 96.8 148.7 138.3 120.2 137.5 64.0 109.9 42.6 59.7 139.9 100.5 98.5 42.6 90.0 164.1 26.1 38.8 36.7 38.5 83.5 47.6 128.4 39.4 62.6 53.6 105.8 129.2 114.9 90.1 43.5 36.8 25.2 130.2 40.7 33.5 65.9 33.8 66.2 40.4 28.3 77.2 31.6 53.9 37.6 19.1 31.1 85.6 23.6 56.0 53.8 59.3 109.0 101.7 118.7 92.4 72.4 160.8 19.6 35.2 57.1 105.6 204.8 60.6 8.1 20.4 24.4 10.5 15.1 9.3 7.4 7.9 8.6 16.3 6.7 8.1 10.9 15.0 9.9 11.9 4.1 5.6 9.7 8.6 10.5 9.5 10.1 9.6 9.4 8.6 8.2 9.0 8.8 9.0 9.7 28.2 0.0 11.5 5.2 6.4 15.8 11.3 16.1 12.5 4.6 13.4 12.3 4.8 5.7 14.6 14.7 6.2 20.6 6.4 31.5 0.0 9.9 28.9 16.3 19.5 18.8 13.2 19.1 16.2 10.9 62.7 17.1 20.4 20.9 8.2 19.7 13.6 77.6 14.3 3.3 14.8 27.5 0.0 14.4 7.2 12.9 15.2 12.9 10.6 12.2 13.3 5.9 6.2 15.6 21.0 9.5 19.8 7.9 4.7 12.7 25.6 12.6 30.2 6.2 0.0 14.3 11.8 50.9 15.4 20.6 20.3 24.8 6.6 19.6 27.6 15.6 ERLIN2 "C8orf2, Erlin-2, NET32, SPFH2, SPG18" ENSG00000147475 "ER lipid raft associated 2" O94905 8 37736601-37758422 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002025, CAB014894" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "CAB014894: , HPA002025: AB_1080077" "unprognostic (5.82e-3)" "unprognostic (2.45e-1)" "prognostic favorable (5.16e-4)" "unprognostic (1.08e-2)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.39e-2)" "unprognostic (1.89e-1)" "unprognostic (3.77e-2)" "unprognostic (6.67e-2)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.78e-3)" "prognostic favorable (6.67e-6)" "unprognostic (4.78e-2)" "unprognostic (2.83e-1)" "unprognostic (3.43e-1)" "unprognostic (2.33e-1)" 20.3 17.8 15.7 14.6 17.3 14.4 25.0 16.5 16.8 20.0 27.2 24.2 17.7 21.2 32.3 17.9 30.1 19.8 17.8 14.2 16.3 40.4 40.8 15.5 11.5 18.0 18.5 30.8 26.2 41.4 8.3 21.2 17.7 25.4 25.0 21.6 29.4 23.8 18.9 15.3 23.6 19.5 17.9 14.6 24.9 17.0 15.6 14.7 46.5 14.1 12.6 16.8 10.3 18.6 39.0 38.5 43.0 31.4 47.3 33.9 47.2 59.1 51.9 31.8 33.2 20.1 50.8 18.9 95.8 63.4 30.3 41.4 31.2 48.4 46.8 11.2 24.2 27.8 22.7 22.7 31.5 17.8 34.1 43.3 49.1 46.3 48.1 39.6 30.7 17.2 51.1 17.7 47.4 18.3 25.8 14.7 45.9 53.8 17.7 17.9 29.9 15.2 42.8 41.9 7.7 20.7 39.3 12.6 35.6 50.1 62.0 27.1 31.1 30.9 26.4 56.8 31.1 24.3 41.0 24.2 55.0 28.4 40.7 1.3 6.5 13.4 4.4 7.0 3.6 4.5 2.7 3.5 5.4 2.3 4.1 3.8 6.1 2.5 9.6 7.6 5.5 3.1 15.7 17.3 16.5 16.8 14.2 16.3 18.0 18.5 17.7 17.9 15.6 18.6 14.7 12.8 14.3 21.5 7.1 9.7 10.0 18.5 13.1 25.2 24.9 20.7 30.2 25.8 22.8 33.1 20.9 17.9 6.0 19.0 9.8 23.8 21.3 31.3 18.5 13.6 11.4 8.0 3.7 22.1 27.0 18.8 17.3 27.8 3.8 14.4 17.5 41.0 20.6 16.8 6.4 24.3 20.3 23.9 6.6 16.8 11.8 16.1 14.2 7.5 12.3 23.5 5.2 11.6 16.7 18.8 17.4 17.7 16.8 15.2 25.4 19.8 47.6 18.7 19.7 19.1 14.8 47.4 18.5 21.9 7.4 15.7 7.1 12.9 25.4 12.8 ERMAP "BTN5, RD, SC" ENSG00000164010 "Erythroblast membrane associated protein (Scianna blood group)" Q96PL5 1 42817122-42844991 "Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 38.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA042573, HPA054672" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus" Cytosol "HPA042573: AB_10794282, HPA054672: " "unprognostic (9.46e-2)" "unprognostic (4.47e-2)" "unprognostic (2.56e-3)" "unprognostic (1.15e-1)" "unprognostic (6.09e-2)" "unprognostic (2.11e-3)" "unprognostic (2.82e-1)" "unprognostic (7.48e-2)" "unprognostic (2.71e-3)" "unprognostic (6.46e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (1.02e-2)" "unprognostic (8.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.48e-1)" "unprognostic (9.48e-2)" 8.0 9.2 3.9 4.7 4.2 30.5 8.3 3.8 4.6 8.6 4.8 7.3 6.5 6.0 15.8 7.2 10.1 7.5 4.3 3.8 5.0 7.1 13.2 7.2 4.9 5.0 4.5 5.5 9.5 8.4 5.8 5.9 4.4 7.8 8.1 4.3 8.6 6.2 2.3 9.3 6.1 6.3 4.4 5.2 7.8 4.1 4.8 5.3 13.0 3.6 5.4 5.5 3.9 5.0 5.2 7.1 2.1 7.0 7.7 22.4 2.0 10.5 17.8 9.3 9.3 2.9 9.6 4.6 3.5 11.2 4.4 6.5 2.4 3.2 8.3 7.8 8.2 38.3 5.2 2.3 9.5 5.2 18.8 13.7 11.8 4.3 9.9 16.8 6.1 5.6 26.4 4.7 8.6 3.6 2.3 1.6 5.1 3.3 3.8 2.6 2.8 4.3 8.0 8.1 4.7 3.2 9.0 3.3 4.0 3.7 6.6 19.6 9.6 6.9 3.9 5.9 4.8 1.8 4.4 2.0 5.6 5.8 4.4 0.0 4.3 2.1 1.2 4.5 0.6 1.3 1.2 0.9 5.1 0.7 1.0 1.0 1.3 2.2 3.0 1.0 3.2 1.9 3.9 4.2 3.8 4.6 3.8 5.0 5.0 4.5 4.4 4.4 4.8 5.0 2.4 12.8 10.9 9.8 2.9 3.8 2.9 3.2 6.2 1.8 6.6 6.3 2.2 4.3 6.2 3.7 22.9 3.1 4.4 4.8 1.9 3.6 4.3 4.7 6.2 3.3 5.4 81.7 5.5 7.2 1.6 3.6 6.1 5.6 2.5 10.4 3.6 12.9 7.8 11.8 2.2 4.4 0.0 11.7 2.9 25.7 2.8 7.4 5.4 14.0 7.1 4.8 1.0 9.5 10.6 4.8 3.9 4.1 2.1 2.9 3.5 4.0 6.5 4.5 0.0 4.7 2.6 0.1 0.7 5.7 3.8 2.9 2.3 7.4 5.5 2.3 ERN1 "IRE1, IRE1P" ENSG00000178607 "Endoplasmic reticulum to nucleus signaling 1" O75460 17 64039080-64130819 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Transcription, Transcription regulation, Unfolded protein response" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 53.0;pancreas: 66.7" "Cell type enhanced" "Detected in many" "Plasma cells: 325.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 17.9" "Group enriched" "Detected in many" 5 "dendritic cells: 7.7;granulocytes: 17.9;T-cells: 9.0" "Cell line enhanced" "Detected in many" "Karpas-707: 74.6;RPMI-8226: 40.2;U-266/70: 77.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009495, HPA027730" Supported NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB009495: AB_2098712, HPA027730: AB_10602494" "unprognostic (2.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.89e-1)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (2.81e-2)" "unprognostic (9.14e-2)" "unprognostic (2.72e-2)" "unprognostic (4.55e-1)" "unprognostic (6.17e-2)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.65e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (3.11e-2)" 9.5 53.0 1.5 5.4 1.7 13.4 7.5 2.6 3.2 22.6 2.1 7.7 6.3 10.1 6.4 9.5 14.3 6.2 6.1 1.6 2.4 5.6 23.5 16.5 5.8 1.7 1.0 16.9 66.7 4.3 19.5 5.6 1.3 9.9 4.5 8.8 15.7 7.1 6.8 11.3 10.6 5.6 1.0 15.8 16.2 2.8 1.6 6.8 10.2 2.4 6.6 8.3 11.7 1.7 4.0 4.0 2.2 4.8 4.8 4.4 9.8 4.1 9.7 2.8 1.3 2.5 2.3 6.6 3.2 2.8 3.5 3.6 1.9 4.5 6.1 1.6 1.5 6.0 3.2 2.4 19.6 3.2 2.1 3.8 8.1 6.4 21.5 3.5 5.0 4.7 4.2 74.6 2.8 3.9 4.5 1.0 0.6 3.6 3.2 4.2 4.2 40.2 1.1 5.5 7.1 3.5 4.3 6.1 5.7 3.5 3.8 5.9 5.9 2.5 4.1 6.4 2.7 77.4 23.9 4.8 4.0 2.1 4.2 17.9 0.9 0.4 4.9 0.4 9.0 0.2 3.3 4.1 0.4 0.3 0.9 0.9 4.9 2.5 0.3 7.7 0.8 1.0 1.5 1.7 2.6 3.2 1.6 2.4 1.7 1.0 1.3 1.0 1.6 1.7 31.9 0.0 36.1 7.2 27.8 22.0 54.3 8.3 15.4 4.0 35.0 29.7 8.6 11.5 8.6 12.9 6.2 8.1 106.4 10.0 1.9 12.6 2.3 26.1 49.1 18.3 79.7 11.2 8.6 27.3 8.8 42.2 52.0 79.4 8.2 11.8 13.9 26.8 8.0 3.3 6.1 8.2 8.2 15.7 71.3 1.7 4.7 60.4 74.7 12.2 10.2 3.5 28.8 6.0 4.6 17.9 7.3 6.0 325.8 44.7 7.9 4.4 6.1 26.5 0.0 19.0 25.7 4.0 4.1 27.7 45.0 54.9 88.2 12.0 9.6 60.1 ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690310-23713226 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 19.5;gallbladder: 17.0;intestine: 28.9;salivary gland: 22.9;stomach 1: 51.9" "Cell type enhanced" "Detected in some" "Club cells: 38.4;Distal enterocytes: 80.2;Gastric mucus-secreting cells: 193.7;Intestinal goblet cells: 143.9;Paneth cells: 37.2;Undifferentiated cells: 70.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.0;pancreatic cancer: 19.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 43.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA076875 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum, Cytosol" "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" 0.1 0.4 0.1 3.0 0.1 0.0 0.1 0.6 0.4 19.5 0.2 28.9 12.9 0.0 0.0 0.9 0.4 17.0 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 0.2 3.5 23.0 0.0 22.9 0.1 0.0 0.2 12.4 0.9 0.0 0.0 51.9 0.1 0.1 0.0 0.0 0.0 0.0 4.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.6 0.4 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.4 0.0 0.0 1.1 0.0 0.8 0.0 1.5 6.8 0.0 0.0 0.0 0.0 0.5 20.0 38.4 0.0 0.0 0.5 0.0 80.2 0.0 2.3 0.1 0.5 0.2 0.1 10.8 0.0 0.2 1.9 0.0 0.1 193.7 1.6 4.5 0.1 0.0 0.0 0.1 0.0 0.1 143.9 6.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 33.1 37.2 0.0 0.5 1.3 6.1 0.1 16.9 0.0 0.0 1.7 1.6 0.0 0.2 0.0 0.0 0.1 0.4 0.0 70.9 11.1 ERO1A "ERO1-alpha, Ero1alpha, ERO1L" ENSG00000197930 "Endoplasmic reticulum oxidoreductase 1 alpha" Q96HE7 14 52639915-52695900 "Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 172.5" "Cell type enhanced" "Detected in many" "Ductal cells: 221.3;Extravillous trophoblasts: 215.8;Pancreatic endocrine cells: 264.7;Prostatic glandular cells: 171.4;Urothelial cells: 145.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026653, HPA030053, CAB034294" Enhanced "Intracellular and membrane" NA NA 110000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB034294: AB_2098744, HPA026653: AB_1848254, HPA030053: AB_10601467" "unprognostic (8.64e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.86e-2)" "unprognostic (5.89e-2)" "unprognostic (5.69e-3)" "unprognostic (4.23e-2)" "prognostic unfavorable (7.59e-4)" "prognostic unfavorable (1.10e-5)" "unprognostic (4.98e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (2.27e-4)" "unprognostic (3.17e-1)" "prognostic unfavorable (6.54e-9)" "unprognostic (9.19e-2)" "unprognostic (2.78e-2)" "unprognostic (4.58e-1)" "unprognostic (5.03e-2)" 17.9 8.6 12.2 20.4 11.7 47.0 16.4 11.8 12.9 59.0 11.3 18.5 17.9 12.0 15.1 172.5 10.0 18.9 15.5 12.1 16.6 14.6 31.2 15.2 14.9 11.7 13.3 8.5 18.9 11.1 12.6 44.4 12.8 9.6 17.8 30.6 37.4 14.0 9.1 18.9 16.5 12.0 9.9 14.6 29.0 5.4 15.1 8.3 13.4 8.2 30.4 32.6 62.4 10.9 100.6 24.2 19.9 21.4 54.4 61.3 38.0 42.4 52.7 34.1 56.9 33.4 158.0 26.3 50.7 28.3 42.0 61.1 27.1 84.1 84.9 22.0 14.5 3.6 25.1 42.1 46.2 60.2 72.1 54.5 54.2 43.9 44.5 79.9 48.2 32.3 18.1 50.8 46.2 15.8 36.0 37.8 11.8 46.5 15.5 21.5 59.8 38.1 52.3 97.1 18.5 49.6 28.9 17.8 39.4 25.7 24.8 22.3 40.0 60.7 29.5 49.6 37.4 26.9 28.8 22.7 88.0 30.3 28.7 20.6 5.9 11.7 5.0 6.9 11.0 4.6 9.4 6.3 4.9 3.1 5.5 5.5 14.7 6.7 9.4 3.7 11.9 2.5 12.2 11.7 11.8 12.9 12.1 16.6 11.7 13.3 12.8 9.9 15.1 10.9 33.8 16.0 27.6 0.0 18.8 0.0 79.2 0.0 19.4 23.4 29.7 11.8 0.0 38.6 15.5 38.6 16.7 24.3 23.3 33.4 3.9 221.3 0.6 32.4 23.8 32.6 10.9 9.9 0.0 130.6 215.8 20.5 56.1 64.0 6.3 10.9 21.0 62.5 42.9 42.1 0.0 10.7 0.0 42.7 0.0 1.6 6.2 49.7 0.0 0.0 45.0 12.2 15.5 0.0 0.0 264.7 18.1 12.8 60.0 171.4 29.0 15.1 13.1 26.4 19.7 14.6 20.9 0.6 3.6 25.7 0.0 91.4 32.1 10.4 20.3 145.8 ERO1B "ERO1-L(beta), Ero1beta, ERO1LB" ENSG00000086619 "Endoplasmic reticulum oxidoreductase 1 beta" Q86YB8 1 236215101-236281958 "Predicted intracellular proteins" "Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 153.9" "Cell type enhanced" "Detected in many" "dendritic cells: 72.8;Early spermatids: 133.4;Spermatocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.4" "Group enriched" "Detected in all" 5 "dendritic cells: 6.0;granulocytes: 15.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028085 Enhanced "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA028085: AB_10601214" "unprognostic (1.16e-1)" "unprognostic (1.33e-3)" "unprognostic (1.00e-1)" "unprognostic (1.41e-1)" "unprognostic (1.07e-1)" "unprognostic (9.80e-2)" "unprognostic (2.49e-2)" "prognostic favorable (7.53e-5)" "unprognostic (1.73e-2)" "unprognostic (2.85e-2)" "unprognostic (4.65e-2)" "unprognostic (5.90e-2)" "unprognostic (8.26e-3)" "unprognostic (7.87e-2)" "unprognostic (3.37e-1)" "unprognostic (2.22e-3)" "unprognostic (8.09e-3)" 5.8 5.5 4.2 5.6 4.1 7.3 7.7 8.5 5.1 5.1 4.3 5.1 10.2 5.1 21.3 2.8 4.9 9.1 4.9 4.5 4.8 8.3 18.8 5.2 7.0 3.7 3.6 6.4 153.9 14.8 9.7 5.2 3.4 5.8 3.2 17.3 8.0 5.4 3.3 3.3 5.4 5.0 2.9 8.3 46.8 28.3 3.1 5.7 27.2 3.9 6.3 4.7 4.0 5.1 2.0 2.3 3.9 3.4 3.0 1.8 4.5 3.1 2.9 2.2 1.7 0.7 2.2 5.5 8.2 4.8 8.3 1.0 1.8 2.8 3.0 5.8 11.1 1.6 0.3 2.1 7.9 2.1 0.9 3.5 5.6 3.8 7.3 4.5 2.6 5.0 0.8 14.2 2.7 1.1 0.9 0.9 1.5 0.3 0.7 11.3 2.6 1.5 4.0 4.7 7.8 4.6 10.2 3.3 8.7 2.0 7.9 9.5 2.5 3.2 2.8 3.2 4.2 9.3 0.6 3.4 4.3 3.1 5.0 15.4 1.5 3.0 2.2 1.6 1.9 1.5 1.2 1.5 1.6 2.1 1.7 1.7 3.1 1.1 0.7 6.0 1.2 0.8 4.2 4.1 8.5 5.1 4.5 4.8 3.7 3.6 3.4 2.9 3.1 5.1 33.4 9.6 9.4 0.0 47.8 0.0 17.9 0.0 45.5 20.7 27.9 23.7 0.0 27.1 3.1 16.5 14.6 12.7 72.8 0.2 1.9 5.3 133.4 1.7 13.2 12.8 14.6 5.5 0.0 16.9 5.1 16.9 32.1 3.9 5.1 9.6 17.5 26.4 6.9 25.2 0.0 5.3 0.0 21.5 0.0 25.6 19.3 34.5 0.0 0.0 11.9 12.2 29.9 0.0 0.0 9.9 0.2 11.3 69.5 18.4 2.7 7.7 1.5 55.4 0.0 36.0 15.1 94.3 14.9 13.6 0.0 22.6 43.8 2.8 1.8 11.0 ERP27 "C12orf46, FLJ32115, PDIA8" ENSG00000139055 "Endoplasmic reticulum protein 27" Q96DN0 12 14914039-14938537 "Predicted intracellular proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "pancreas: 1802.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Collecting duct cells: 40.5;Distal tubular cells: 164.4;Endometrial ciliated cells: 40.7;Exocrine glandular cells: 39.7;Theca cells: 104.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "RT4: 102.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA039636, HPA052851" Enhanced "Intracellular and membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA039636: AB_10795403, HPA052851: AB_2681972" "unprognostic (9.02e-3)" "unprognostic (2.53e-1)" "unprognostic (1.41e-1)" "unprognostic (4.69e-2)" "unprognostic (8.70e-2)" "unprognostic (3.92e-3)" "unprognostic (2.70e-1)" "unprognostic (1.48e-2)" "unprognostic (2.37e-3)" "unprognostic (5.33e-2)" "unprognostic (2.34e-2)" "unprognostic (1.88e-1)" "unprognostic (7.89e-2)" "unprognostic (4.55e-2)" "unprognostic (8.98e-2)" "unprognostic (1.76e-3)" "unprognostic (3.45e-2)" 0.9 0.8 1.2 3.7 0.3 5.3 6.7 0.0 1.4 6.7 0.2 0.8 1.1 1.1 2.1 1.4 77.4 1.0 1.0 0.9 0.0 27.0 0.6 11.9 5.0 0.1 0.0 1.6 1802.9 1.4 1.0 2.5 0.1 2.0 1.3 0.7 5.7 2.8 0.3 2.0 2.5 0.8 0.1 4.2 3.7 0.4 0.0 2.5 8.3 0.4 3.8 18.0 0.9 0.0 3.4 0.0 0.0 0.5 0.3 0.0 0.7 0.2 0.0 0.0 0.0 1.1 19.5 1.6 2.0 0.0 0.0 4.0 0.0 0.2 0.0 0.1 0.0 4.5 0.1 19.3 0.0 1.5 2.2 0.1 0.0 0.0 0.0 0.1 0.5 4.9 0.0 0.9 0.0 7.0 3.2 5.9 0.0 0.2 0.0 1.8 0.0 0.4 0.6 102.3 0.1 0.0 0.0 15.8 0.0 1.8 0.7 4.8 2.4 0.3 0.1 0.0 0.0 0.1 0.1 3.1 0.0 1.4 0.0 3.0 3.4 4.1 4.8 3.8 6.3 1.5 4.3 3.4 2.5 1.5 5.4 5.8 1.5 1.3 4.6 0.2 5.9 2.6 1.2 0.3 0.0 1.4 0.9 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.5 41.7 20.8 0.0 1.6 0.4 2.7 0.2 0.0 0.2 8.7 2.2 0.2 0.0 17.9 40.5 0.0 5.9 2.4 0.2 164.4 25.0 0.0 40.7 1.1 0.8 1.8 0.0 0.0 39.7 14.1 1.1 0.0 8.7 1.3 0.2 0.4 0.0 1.5 0.0 0.0 0.0 0.0 1.9 1.2 0.0 1.8 1.1 0.0 3.7 2.5 3.1 4.1 0.0 0.0 18.9 3.5 0.0 1.3 1.8 0.0 8.6 18.0 0.2 0.0 0.0 1.0 0.0 0.0 0.4 0.4 0.8 3.9 104.3 0.3 14.3 ERP29 "C12orf8, ERp28, ERp31, PDI-DB, PDIA9" ENSG00000089248 "Endoplasmic reticulum protein 29" P30040 12 112013348-112023449 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039363, HPA039456" Enhanced Uncertain Nucleoplasm,Microtubules "Intracellular and membrane" NA NA 900000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Microtubules Nucleoplasm "HPA039363: AB_10673422, HPA039456: AB_10672963" "unprognostic (2.70e-2)" "unprognostic (1.16e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.43e-5)" "unprognostic (1.13e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (1.04e-2)" "unprognostic (2.00e-1)" "unprognostic (1.21e-1)" "unprognostic (5.10e-3)" "unprognostic (2.58e-1)" "unprognostic (3.21e-1)" "unprognostic (2.74e-3)" "unprognostic (3.34e-1)" "unprognostic (1.76e-1)" "unprognostic (6.26e-2)" 62.7 100.9 56.9 77.9 58.0 202.3 84.0 65.1 62.0 78.4 91.1 94.5 100.7 60.5 109.8 91.5 74.8 64.1 59.0 56.0 68.7 93.0 179.9 78.8 123.8 61.1 62.6 78.9 174.6 123.6 99.1 73.0 64.2 93.4 91.3 68.3 122.7 87.4 34.3 113.3 96.1 47.1 57.8 118.3 131.4 57.6 60.8 107.6 90.4 34.3 111.2 75.9 71.0 61.6 145.4 137.2 98.8 194.2 367.4 143.7 211.3 139.2 163.7 108.5 139.3 215.2 164.4 152.7 106.4 244.5 117.8 175.4 187.8 181.2 89.3 133.7 104.2 174.3 150.1 239.2 246.8 432.1 164.0 207.5 227.6 178.4 201.6 287.4 156.1 157.9 203.2 277.3 84.7 166.6 140.9 765.7 161.5 513.1 102.5 114.2 120.9 501.2 229.8 213.5 88.6 119.8 173.6 140.1 426.1 187.4 177.1 575.7 116.5 92.6 142.7 88.8 103.3 303.4 379.8 128.0 157.8 268.5 73.2 96.2 241.4 346.2 131.6 178.8 140.4 259.1 170.7 164.1 229.7 264.1 186.5 154.9 47.5 86.5 170.9 455.8 179.6 307.4 56.9 58.0 65.1 62.0 56.0 68.7 61.1 62.6 64.2 57.8 60.8 61.6 102.6 83.3 183.4 13.7 324.8 141.4 205.5 249.3 132.6 125.3 207.8 199.9 91.6 198.8 178.0 185.8 110.5 497.7 396.6 210.1 93.9 239.5 7.7 142.1 84.9 114.9 197.9 134.4 14.4 211.8 405.3 118.3 131.5 149.9 88.8 164.4 146.3 346.6 373.1 80.8 20.6 280.6 343.8 306.9 192.6 16.6 128.9 230.4 168.9 12.2 269.0 152.8 160.6 11.6 22.8 128.7 288.0 106.8 350.1 195.4 355.5 274.6 187.0 164.9 52.6 79.2 112.2 100.3 195.3 143.1 161.0 441.6 221.7 252.4 285.2 219.8 ERP44 "KIAA0573, PDIA10, TXNDC4" ENSG00000023318 "Endoplasmic reticulum protein 44" Q9BS26 9 99979185-100099000 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001318 Supported "Intracellular and membrane" NA NA 5300000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "HPA001318: AB_1080427" "unprognostic (8.28e-2)" "unprognostic (1.32e-1)" "unprognostic (5.56e-2)" "unprognostic (5.97e-3)" "unprognostic (1.55e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (1.29e-1)" "unprognostic (3.88e-2)" "unprognostic (2.58e-1)" "unprognostic (2.00e-2)" "unprognostic (5.38e-2)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "unprognostic (1.66e-1)" "unprognostic (3.90e-1)" "unprognostic (2.31e-1)" 18.4 17.3 8.1 17.7 8.5 21.3 16.2 12.9 10.5 19.5 10.1 22.0 22.4 15.2 39.3 17.8 13.7 16.7 15.9 8.2 9.1 18.0 34.2 18.6 17.9 8.0 8.7 12.4 27.4 18.7 13.3 32.6 8.5 18.9 23.6 15.8 20.8 18.3 11.6 12.9 23.8 16.8 8.4 18.4 24.1 10.6 8.6 14.6 27.1 11.6 18.6 19.3 14.1 9.0 18.5 14.7 20.7 23.6 73.5 34.9 37.6 39.9 54.2 27.6 36.3 31.2 52.4 47.3 25.7 45.5 41.1 65.9 25.7 28.1 24.9 24.5 14.4 17.8 14.3 22.8 64.3 32.2 27.0 39.4 41.5 24.2 34.7 26.2 34.2 15.7 34.7 35.7 22.7 28.8 22.1 22.6 21.5 72.0 18.9 19.2 34.7 32.9 35.9 20.9 16.2 18.9 32.8 40.2 28.9 30.5 15.0 32.8 23.8 20.5 19.2 27.4 17.7 20.5 19.3 15.8 31.3 21.0 28.3 32.8 45.7 42.7 20.2 49.2 19.5 28.1 19.9 22.1 37.4 26.5 15.1 17.6 41.5 27.4 62.3 23.4 23.5 37.7 8.1 8.5 12.9 10.5 8.2 9.1 8.0 8.7 8.5 8.4 8.6 9.0 72.3 54.5 41.8 38.8 77.5 43.3 80.3 146.6 29.0 34.3 33.9 25.3 34.7 54.3 84.6 33.1 18.8 141.4 72.5 90.0 17.6 104.4 8.4 42.2 61.4 62.5 53.1 38.3 69.4 111.8 150.5 72.0 57.1 62.3 71.0 54.2 64.6 73.3 165.7 30.3 70.0 118.1 73.2 79.5 101.9 7.7 61.2 102.2 64.0 85.3 128.5 32.7 61.8 45.8 68.9 92.8 90.0 67.7 97.9 75.9 111.2 51.4 60.2 30.6 72.3 48.9 95.9 83.3 41.4 40.0 49.6 229.3 60.3 87.5 88.9 84.2 ERV3-1 "envR, ERV-R, ERV3, H-PLK, HERV-R" ENSG00000213462 "Endogenous retrovirus group 3 member 1, envelope" Q14264 7 64990356-65006743 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 27.7" "HPA017209, HPA046508" Enhanced Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA017209: AB_2732419, HPA046508: AB_2732525" "unprognostic (2.74e-2)" "unprognostic (1.84e-1)" "unprognostic (2.11e-1)" "unprognostic (1.27e-2)" "unprognostic (4.48e-1)" "unprognostic (2.03e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" "unprognostic (4.05e-3)" "unprognostic (3.55e-1)" "unprognostic (1.57e-2)" "unprognostic (4.45e-2)" "unprognostic (4.27e-3)" "unprognostic (2.11e-1)" "unprognostic (2.19e-1)" "unprognostic (9.39e-2)" "unprognostic (1.88e-2)" 22.8 33.0 4.8 8.5 4.5 9.3 15.0 4.1 6.4 10.0 5.1 5.7 3.5 10.0 32.5 15.2 8.0 16.4 6.2 4.7 6.2 4.8 3.2 9.7 5.7 6.2 7.9 7.3 5.3 15.3 8.2 13.4 5.4 7.3 5.7 13.5 12.1 7.5 3.6 12.3 4.5 7.6 4.8 6.9 6.3 8.7 5.9 6.6 7.6 1.8 7.4 6.2 11.5 5.1 3.3 1.0 17.4 27.7 11.3 4.7 12.4 5.7 6.3 2.0 4.6 1.2 20.5 5.5 5.3 2.2 4.0 3.9 2.6 1.5 3.2 4.1 1.5 2.8 1.6 11.5 1.0 6.7 3.7 5.1 1.6 1.8 0.6 10.4 11.6 6.0 12.7 10.3 8.1 8.1 4.9 5.0 5.1 10.8 1.2 11.4 0.7 3.7 3.5 6.8 3.6 16.8 6.2 1.9 0.7 18.9 4.7 16.4 9.2 6.7 1.0 5.1 2.8 3.2 7.8 1.6 5.7 20.8 4.1 0.0 1.0 2.4 0.6 1.8 0.5 0.4 0.1 0.4 0.8 0.5 0.3 0.4 7.0 1.1 0.5 0.4 1.2 0.6 4.8 4.5 4.1 6.4 4.7 6.2 6.2 7.9 5.4 4.8 5.9 5.1 7.1 3.2 13.1 17.9 32.5 4.2 15.6 17.0 7.4 24.8 13.7 10.4 2.1 24.3 25.5 16.5 29.2 16.5 21.6 4.4 9.8 14.4 7.3 6.2 8.6 10.9 13.8 19.4 12.2 17.9 12.7 8.3 12.8 5.9 8.2 20.4 13.6 3.6 9.7 18.5 13.0 9.1 16.2 21.8 16.5 4.8 11.5 19.8 10.6 14.0 16.7 11.3 36.0 24.1 14.0 17.6 7.8 9.8 10.0 12.5 15.4 4.9 14.0 21.4 6.6 7.6 8.7 12.2 11.8 8.6 5.7 40.2 20.5 10.7 6.7 31.1 ERVH48-1 "C21orf105, NDUFV3-AS1, SUPYN" ENSG00000233056 "Endogenous retrovirus group 48 member 1" M5A8F1 21 42916803-42925646 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 65 "placenta: 152.2" "Group enriched" "Detected in some" 8 "Cytotrophoblasts: 130.7;Extravillous trophoblasts: 258.3;Syncytiotrophoblasts: 88.8" "Cancer enriched" "Detected in some" 18 "testis cancer: 74.5" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 6 "neutrophil: 7.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.7" "Cell line enriched" "Detected in some" 7 "BEWO: 296.4" "Secreted in female reproductive system" NA NA 57000 "Cluster 1: Neutrophils - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (5.28e-2)" "unprognostic (5.92e-2)" "unprognostic (5.66e-2)" "unprognostic (9.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.90e-1)" "unprognostic (1.92e-2)" "unprognostic (3.48e-1)" "unprognostic (1.52e-2)" "unprognostic (7.74e-2)" "unprognostic (3.12e-3)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.83e-2)" "unprognostic (1.08e-2)" 0.1 0.4 0.5 0.2 0.8 0.7 0.1 2.3 1.3 0.0 0.7 0.1 0.3 0.2 0.2 0.1 0.1 0.3 0.1 0.6 0.0 0.1 0.1 0.4 0.4 0.6 0.0 0.2 0.7 0.0 152.2 0.7 0.7 0.0 1.5 0.4 0.0 0.4 0.8 0.5 0.0 0.0 0.4 0.3 1.4 0.4 1.3 0.4 0.0 0.0 0.0 0.5 0.0 0.3 0.7 0.1 0.0 0.0 296.4 0.1 0.0 0.0 0.0 11.9 0.2 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 2.8 1.4 0.4 0.1 1.2 0.2 0.0 0.0 0.2 0.0 0.1 11.1 1.0 0.7 0.6 0.0 0.2 8.2 5.0 0.9 0.0 0.3 6.4 0.3 0.1 0.0 0.2 0.4 0.3 0.1 0.0 0.0 44.6 0.3 0.2 0.3 0.2 0.6 0.4 0.1 0.9 2.9 0.5 0.4 3.0 0.2 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.6 7.7 0.0 0.0 0.0 0.0 0.0 0.5 0.8 2.3 1.3 0.6 0.0 0.6 0.0 0.7 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 130.7 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.4 0.0 0.0 0.0 0.0 258.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 19.2 3.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.0 88.8 0.0 0.0 0.0 0.0 ERVK3-1 HERV-K(HML6-1) ENSG00000142396 "Endogenous retrovirus group K3 member 1" 19 58305319-58315663 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" "unprognostic (2.06e-3)" "unprognostic (2.32e-1)" "unprognostic (2.71e-1)" "unprognostic (7.16e-3)" "unprognostic (1.24e-1)" "unprognostic (1.59e-2)" "prognostic unfavorable (9.45e-4)" "unprognostic (7.88e-2)" "unprognostic (5.91e-3)" "unprognostic (3.43e-2)" "unprognostic (3.88e-3)" "unprognostic (2.56e-3)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.04e-1)" "unprognostic (1.38e-1)" "unprognostic (2.46e-1)" "unprognostic (1.18e-3)" 30.1 32.8 37.3 20.5 38.0 34.4 36.0 39.7 44.9 25.5 35.4 28.7 26.7 25.0 38.4 25.8 24.2 18.9 34.7 40.8 42.6 45.2 41.1 29.2 31.9 39.4 41.5 26.2 27.0 39.1 35.7 19.8 41.2 33.9 17.7 26.2 24.2 23.7 32.5 27.6 27.3 17.4 38.8 34.9 30.6 18.1 39.4 32.5 28.9 24.4 30.8 27.2 23.7 40.7 72.0 139.8 56.8 53.1 33.5 22.4 43.6 47.7 36.7 36.1 34.9 83.8 38.3 49.5 42.0 34.5 51.4 29.2 64.7 43.4 34.3 80.2 258.5 79.3 59.0 73.8 50.6 110.1 51.0 23.4 43.4 58.7 65.6 33.9 25.1 58.2 120.1 59.9 46.4 57.2 99.2 41.6 68.2 85.8 97.1 59.8 60.1 71.8 36.4 103.8 86.4 73.8 57.7 56.4 79.3 54.4 44.1 74.3 31.3 98.2 54.4 30.6 100.3 74.4 224.5 129.4 53.1 64.7 83.0 85.9 39.4 74.0 67.5 43.3 64.2 58.9 60.7 63.7 40.0 57.9 62.3 72.8 34.7 57.8 57.1 67.7 78.3 69.4 37.3 38.0 39.7 44.9 40.8 42.6 39.4 41.5 41.2 38.8 39.4 40.7 21.2 16.0 22.3 0.0 33.2 0.0 6.0 0.0 45.5 20.6 15.0 12.2 6.5 8.6 8.1 5.5 6.2 18.6 24.1 15.5 13.7 25.4 1.0 7.8 10.9 15.2 18.0 16.2 0.0 25.5 8.5 16.4 25.0 10.7 37.3 8.8 8.9 5.6 12.3 16.8 0.0 14.4 0.0 6.3 0.0 1.9 7.8 15.2 0.0 0.0 14.7 11.7 21.6 0.0 0.0 30.0 25.6 14.3 39.6 8.1 23.3 11.9 4.4 12.2 6.6 8.5 14.4 19.3 28.7 29.4 0.0 15.3 31.0 11.5 13.5 5.5 ESM1 ENSG00000164283 "Endothelial cell specific molecule 1" Q9NQ30 5 54977867-55022671 "Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 19.9;thyroid gland: 17.3" "Cell type enriched" "Detected in some" 8 "Endothelial cells: 142.4" "Cancer enriched" "Detected in all" 8 "renal cancer: 65.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "NK-cell: 1.4" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 302.2;TIME: 568.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB047364 Approved "Secreted to blood" NA NA 1540000 340000 "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB047364: " "unprognostic (4.70e-2)" "prognostic unfavorable (2.11e-7)" "unprognostic (2.63e-3)" "unprognostic (2.31e-3)" "unprognostic (4.68e-2)" "unprognostic (1.55e-1)" "unprognostic (6.85e-3)" "unprognostic (1.59e-2)" "unprognostic (1.05e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (4.00e-4)" "unprognostic (7.77e-2)" "unprognostic (1.09e-1)" "unprognostic (7.84e-2)" "unprognostic (2.94e-1)" 1.3 4.2 0.4 0.7 0.7 0.6 0.5 0.2 1.1 2.0 0.8 0.2 0.7 3.6 0.4 0.2 0.2 1.3 3.6 0.3 1.3 19.9 2.6 11.3 1.2 0.5 0.5 0.7 2.3 6.0 2.2 0.4 0.3 3.5 0.0 0.1 6.3 3.7 0.2 0.1 0.8 0.7 0.8 0.9 0.3 0.6 1.6 0.2 17.3 0.2 0.6 1.3 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 79.8 9.5 4.1 1.0 0.0 0.0 0.1 7.4 5.7 2.3 0.0 0.0 1.0 14.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.7 0.4 8.5 302.2 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 568.0 4.7 13.7 39.2 21.3 0.1 0.0 0.0 1.7 0.0 3.8 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.1 0.4 0.7 0.2 1.1 0.3 1.3 0.5 0.5 0.3 0.8 1.6 0.4 6.3 0.0 0.6 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.0 16.1 0.0 0.1 0.1 142.4 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.0 0.7 0.0 2.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.5 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 1.5 1.7 0.1 0.3 0.0 0.1 0.1 0.6 1.1 0.0 0.7 ESPN DFNB36 ENSG00000187017 Espin B1AK53 1 6424776-6461367 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing Actin-binding "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 129.1;retina: 117.8;testis: 145.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 175.5;Early spermatids: 137.5;Late spermatids: 461.6;Muller glia cells: 272.5;Paneth cells: 186.3;Proximal enterocytes: 512.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 13.4;thalamus: 6.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 48.9;Hep G2: 81.5;SK-BR-3: 160.1;T-47d: 53.6" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 2.6" "HPA028674, HPA060220" Enhanced Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA028674: AB_10601316, HPA060220: AB_2684224" "unprognostic (5.06e-2)" "unprognostic (1.18e-2)" "unprognostic (2.69e-1)" "unprognostic (1.28e-1)" "unprognostic (2.19e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (2.28e-1)" "unprognostic (1.16e-1)" "unprognostic (5.71e-2)" "unprognostic (7.48e-3)" "unprognostic (5.53e-2)" "unprognostic (6.26e-3)" "unprognostic (5.51e-2)" "unprognostic (1.16e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-2)" 0.6 5.7 0.4 2.6 1.0 28.0 9.2 13.4 1.0 30.3 0.2 28.2 90.4 2.4 39.9 34.3 18.6 0.3 0.9 0.4 1.7 63.4 129.1 3.2 0.3 0.6 1.3 0.4 0.9 26.8 42.1 0.9 1.1 10.0 6.8 117.8 9.4 6.2 0.8 91.7 89.5 0.8 0.3 0.9 2.7 145.3 6.1 1.6 0.4 0.0 1.7 1.3 22.3 0.5 14.1 0.7 0.6 0.1 0.0 0.0 48.9 0.0 0.0 0.2 0.0 29.9 1.5 0.5 6.5 0.0 0.1 32.6 2.3 0.1 0.0 2.0 0.7 0.4 0.7 81.5 0.0 0.6 2.7 0.1 0.6 0.0 0.0 0.0 0.0 1.0 17.6 0.0 0.0 28.2 0.2 1.0 0.6 3.8 12.2 0.0 0.4 10.9 0.2 0.1 21.0 0.7 3.7 160.1 5.0 0.3 53.6 7.4 15.6 0.1 0.8 0.6 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 1.0 13.4 1.0 0.4 1.7 0.6 1.3 1.1 0.3 6.1 0.5 0.2 0.0 0.6 0.0 0.8 7.8 2.4 4.5 12.5 5.6 10.7 3.9 1.4 11.5 3.8 9.2 68.8 3.0 0.2 175.5 13.7 0.2 137.5 19.1 0.9 0.8 6.0 8.2 0.2 3.1 0.5 0.3 5.6 12.4 0.0 0.0 3.9 109.4 0.2 0.0 0.2 36.3 8.2 3.2 0.9 461.6 3.7 1.5 0.0 0.0 0.0 272.5 0.0 0.0 0.1 0.1 186.3 2.2 0.0 1.6 512.1 102.2 9.0 72.5 0.0 0.0 0.2 12.3 3.9 17.6 22.7 6.6 1.5 0.0 35.3 2.9 ESPNL FLJ42568 ENSG00000144488 "Espin like" Q6ZVH7 2 238100340-238133287 "Predicted intracellular proteins" Hearing Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;intestine: 3.5" "Cell type enhanced" "Detected in some" "B-cells: 1.8;Cardiomyocytes: 2.5;Granulosa cells: 2.0;Muller glia cells: 1.4;Proximal tubular cells: 3.4;Skeletal myocytes: 1.6;Theca cells: 2.2" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 12 "cerebellum: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.8;Daudi: 2.6;fHDF/TERT166: 2.3;HHSteC: 2.6;THP-1: 1.8;U-87 MG: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA055103 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA055103: AB_2682694" "unprognostic (8.04e-2)" "unprognostic (1.29e-1)" "unprognostic (2.34e-2)" "unprognostic (1.18e-3)" "unprognostic (1.51e-2)" "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (3.20e-1)" "unprognostic (1.79e-1)" "unprognostic (2.18e-1)" "unprognostic (2.95e-1)" "unprognostic (2.24e-1)" "unprognostic (3.94e-6)" "unprognostic (3.49e-2)" "unprognostic (8.52e-2)" "unprognostic (1.08e-1)" "unprognostic (5.67e-2)" 0.4 0.3 0.4 0.1 0.2 0.0 0.4 5.0 0.2 0.8 0.9 0.8 0.3 1.0 0.0 0.2 1.5 0.1 0.7 0.4 0.3 0.3 1.6 0.2 0.5 0.2 0.3 2.2 0.3 0.0 2.1 0.1 0.4 0.6 0.0 0.0 0.0 0.8 0.2 0.2 3.5 0.4 0.0 1.1 0.2 0.4 0.2 0.3 1.0 0.0 0.2 0.6 0.4 0.3 0.0 0.0 0.0 1.8 0.3 0.6 0.3 1.0 0.4 0.8 0.8 0.0 0.0 2.6 1.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.9 2.6 0.0 0.5 0.9 0.0 0.1 0.0 0.0 0.0 0.8 0.8 0.0 1.0 0.0 0.0 1.1 0.1 0.0 0.0 0.8 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 5.0 0.2 0.4 0.3 0.2 0.3 0.4 0.0 0.2 0.3 0.1 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.6 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.0 2.0 0.0 0.5 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.3 0.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 1.6 0.3 0.0 0.6 0.0 0.0 0.0 0.4 2.2 0.0 0.0 ESRP1 "FLJ20171, RBM35A" ENSG00000104413 "Epithelial splicing regulatory protein 1" Q6NXG1 8 94641074-94707466 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 107.2;Suprabasal keratinocytes: 79.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 138.3;BEWO: 101.1;CAPAN-2: 140.8;hTCEpi: 226.5;OE19: 142.6;RT4: 99.1;T-47d: 108.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023719, HPA023720, HPA067104" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear bodies" Nucleoplasm "HPA023719: AB_1856124, HPA023720: AB_1856125, HPA067104: AB_2685779" "prognostic unfavorable (9.28e-4)" "unprognostic (7.12e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (4.12e-1)" "unprognostic (6.99e-3)" "unprognostic (2.70e-1)" "unprognostic (2.61e-2)" "unprognostic (5.19e-2)" "unprognostic (5.51e-2)" "prognostic unfavorable (2.05e-4)" "unprognostic (4.48e-2)" "prognostic favorable (1.96e-8)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.96e-2)" "unprognostic (1.29e-1)" 0.2 0.0 0.0 5.2 0.0 0.0 24.2 0.0 0.0 15.5 0.0 57.1 25.2 3.4 29.6 64.2 21.3 8.5 0.1 0.0 0.0 8.5 0.4 15.8 0.0 0.0 0.1 0.1 42.6 28.4 7.2 12.2 0.0 19.9 62.8 0.0 25.9 10.0 0.1 60.6 22.0 2.5 0.0 0.0 38.6 0.6 0.4 5.2 36.6 0.0 15.3 22.5 28.8 0.0 138.3 0.0 0.0 0.2 0.0 0.0 101.1 0.0 0.0 0.0 0.0 44.6 140.8 0.0 3.8 0.0 0.1 81.6 3.8 70.9 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 226.5 0.0 1.4 0.0 0.0 10.7 0.0 0.0 0.0 67.3 1.9 0.4 12.4 142.6 3.4 0.0 0.0 18.3 17.4 99.1 35.1 0.3 0.0 21.0 14.0 21.4 108.0 0.9 0.0 0.1 0.2 0.1 0.3 12.0 13.8 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 38.5 36.7 0.0 0.6 44.6 18.9 30.4 35.9 0.0 29.4 18.0 1.0 21.5 32.4 27.6 0.0 55.1 0.5 76.2 13.7 19.6 12.9 47.1 3.7 0.9 33.1 0.0 2.6 27.5 69.1 0.9 58.1 46.5 1.3 0.0 0.4 0.1 6.0 0.0 0.4 107.2 16.2 0.0 3.2 10.3 0.0 0.5 24.9 0.0 0.6 0.0 0.0 0.5 0.4 21.7 48.1 0.7 1.8 25.1 25.5 0.3 35.0 0.0 0.0 0.0 1.2 0.6 0.9 71.3 79.1 62.1 0.8 0.0 73.9 40.1 ETV6 TEL ENSG00000139083 "ETS variant transcription factor 6" P41212 12 11649674-11895377 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 137.2;Microglial cells: 216.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 85.1;NB-4: 45.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000264 Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoli Cytosol "HPA000264: AB_611466" "unprognostic (4.03e-3)" "unprognostic (3.08e-2)" "unprognostic (7.54e-3)" "unprognostic (2.60e-1)" "unprognostic (2.07e-1)" "unprognostic (1.35e-3)" "unprognostic (2.74e-2)" "unprognostic (4.02e-2)" "unprognostic (3.16e-1)" "unprognostic (9.46e-2)" "prognostic unfavorable (9.38e-5)" "unprognostic (1.15e-1)" "prognostic unfavorable (4.66e-8)" "unprognostic (1.33e-2)" "unprognostic (5.99e-2)" "unprognostic (8.92e-2)" "prognostic favorable (1.54e-5)" 16.9 8.8 4.8 16.3 4.4 40.9 20.0 4.8 5.6 9.4 3.6 15.2 7.5 7.9 11.1 9.5 8.0 9.7 6.6 4.2 4.7 9.2 9.3 16.2 12.8 9.2 6.0 5.0 9.6 5.6 5.3 8.1 6.9 13.5 11.2 2.6 33.3 6.8 5.5 24.3 14.1 9.2 6.8 16.7 8.4 3.5 6.8 17.3 8.9 2.7 14.7 15.0 8.4 6.3 5.6 7.5 6.7 11.6 5.0 4.7 8.1 4.1 6.9 5.2 6.1 0.5 25.9 4.7 4.0 7.0 6.1 7.1 3.0 12.4 6.2 85.1 1.4 29.9 4.0 2.8 6.2 32.0 31.2 9.3 7.5 5.1 10.5 9.9 15.9 21.3 2.3 15.3 4.7 3.6 18.1 45.3 10.9 5.9 2.0 5.1 6.3 12.3 11.9 34.8 1.3 6.8 8.1 7.7 7.7 10.6 2.6 19.9 18.1 11.6 9.8 3.9 8.8 6.7 5.5 2.6 7.6 0.2 13.6 6.2 4.5 5.9 1.1 5.6 1.6 2.3 1.7 1.1 3.5 1.7 1.0 0.6 9.8 2.1 6.8 5.3 1.2 1.2 4.8 4.4 4.8 5.6 4.2 4.7 9.2 6.0 6.9 6.8 6.8 6.3 38.3 6.4 9.6 84.2 37.7 14.9 31.8 27.2 10.8 3.1 66.7 57.8 9.1 21.5 30.7 14.7 6.2 15.0 21.5 45.7 1.9 17.9 17.6 45.3 17.5 37.5 32.4 33.6 63.6 35.9 4.3 12.9 20.9 69.7 10.8 24.0 38.6 10.9 18.3 0.0 117.7 28.9 22.4 53.3 137.2 4.5 7.8 62.6 28.4 216.4 55.7 4.3 8.2 106.6 37.0 38.6 31.6 10.9 71.4 34.2 15.4 11.5 39.3 3.9 19.7 17.6 34.2 0.6 5.4 17.3 22.4 8.6 20.9 21.5 22.5 71.8 EVA1A "FAM176A, FLJ13391, TMEM166" ENSG00000115363 "Eva-1 homolog A, regulator of programmed cell death" Q9H8M9 2 75469302-75569722 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 191.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Cytotrophoblasts: 43.3;Hepatocytes: 78.1;Proximal tubular cells: 77.3;Syncytiotrophoblasts: 124.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 85.7;U-138 MG: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008055 Approved Supported "Vesicles,Plasma membrane" NA Yes "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Plasma membrane" "HPA008055: AB_1080308" "unprognostic (2.72e-1)" "unprognostic (2.61e-2)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.60e-2)" "unprognostic (5.02e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.67e-4)" "unprognostic (7.33e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.80e-4)" "unprognostic (8.19e-2)" "unprognostic (4.37e-2)" "unprognostic (2.43e-2)" "unprognostic (9.07e-2)" 1.1 0.5 0.2 1.1 0.9 0.1 3.4 0.6 0.5 9.8 0.2 0.7 1.7 2.8 9.6 0.4 3.7 1.2 1.6 0.2 0.3 20.0 191.6 20.7 0.4 1.1 0.5 0.5 23.8 7.6 1.1 17.3 0.9 0.9 0.7 0.5 8.9 2.2 1.2 2.7 1.8 2.0 0.7 10.8 0.6 2.9 0.8 5.1 1.8 1.6 0.3 0.8 0.8 0.8 1.0 14.5 1.5 0.4 3.1 21.2 1.4 68.0 45.3 59.2 30.1 0.5 1.2 0.1 6.3 85.7 54.2 9.4 1.7 14.4 36.8 0.0 1.1 0.0 2.5 45.7 2.2 0.0 0.1 15.0 8.3 73.2 33.3 59.0 37.2 0.0 0.0 0.0 46.1 0.0 0.1 0.0 3.3 0.2 23.5 7.9 0.1 0.0 32.5 0.5 0.9 1.6 6.2 0.4 53.7 2.2 0.2 0.3 31.0 110.3 46.3 2.0 71.9 0.7 0.1 0.3 62.5 0.0 59.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.6 0.5 0.2 0.3 1.1 0.5 0.9 0.7 0.8 0.8 6.1 41.7 35.4 1.0 0.9 2.8 13.7 14.3 3.4 1.2 11.7 12.3 0.3 1.5 23.0 11.0 0.0 43.3 0.4 0.1 27.4 30.5 12.2 13.3 1.4 4.8 1.8 0.0 1.1 16.1 25.9 4.7 0.0 11.4 0.0 0.0 2.2 78.1 3.5 0.0 0.9 1.1 4.1 0.8 1.2 9.4 0.3 0.6 28.4 2.8 0.1 0.0 0.0 1.5 0.9 9.7 0.0 0.7 0.0 12.3 0.5 77.3 1.7 0.1 0.0 2.2 9.0 2.2 0.9 1.1 0.9 124.8 1.1 0.0 1.6 10.5 EVA1B "C1orf78, FAM176B, FLJ10647" ENSG00000142694 "Eva-1 homolog B" Q9NVM1 1 36322031-36324154 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 143.9;Extravillous trophoblasts: 250.3;Syncytiotrophoblasts: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 23.3;BJ: 29.0;BJ hTERT+: 22.4;HSkMC: 20.4;NB-4: 41.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041928, HPA043537" Approved Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA041928: AB_2677752, HPA043537: AB_2678538" "prognostic favorable (4.58e-4)" "unprognostic (5.66e-3)" "unprognostic (1.04e-3)" "unprognostic (3.20e-2)" "unprognostic (1.22e-2)" "unprognostic (4.00e-3)" "prognostic unfavorable (4.82e-4)" "unprognostic (1.45e-1)" "unprognostic (8.33e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.87e-2)" "unprognostic (3.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.02e-1)" 26.8 19.4 5.5 3.4 5.4 2.0 35.8 5.5 6.4 41.8 7.5 19.8 2.5 34.0 0.6 12.2 21.9 1.3 19.9 5.0 5.9 39.2 8.5 26.1 1.9 6.8 6.4 30.2 7.8 1.9 9.4 9.0 6.0 29.0 0.4 0.0 28.7 2.9 5.7 24.0 15.8 1.6 7.0 37.6 14.2 7.5 6.6 0.5 33.9 1.0 0.5 22.0 30.1 5.7 0.7 2.7 1.6 3.0 7.9 23.3 6.8 29.0 22.4 5.4 6.3 0.2 2.1 0.0 8.5 9.2 1.0 0.2 0.2 1.1 1.1 3.3 6.0 3.6 0.6 1.3 17.4 0.1 0.6 20.4 0.0 6.9 0.3 0.9 8.7 0.1 1.4 1.0 3.6 0.2 0.1 41.7 1.7 0.0 10.4 1.5 0.3 7.1 4.6 0.0 0.1 3.9 2.8 1.1 13.3 1.1 0.0 2.7 12.7 7.9 0.0 10.5 2.7 0.3 0.0 0.1 2.9 1.8 7.1 4.0 0.9 0.0 0.2 0.3 0.6 0.0 0.3 0.5 0.5 0.0 0.0 0.0 1.7 1.6 0.1 0.0 1.2 0.1 5.5 5.4 5.5 6.4 5.0 5.9 6.8 6.4 6.0 7.0 6.6 5.7 82.8 0.0 0.0 2.3 6.2 16.2 19.3 7.3 0.0 0.0 143.9 90.6 2.2 1.5 5.1 7.3 0.0 54.7 8.4 0.3 1.9 20.2 7.1 9.4 88.4 53.9 0.0 0.8 0.0 15.2 250.3 56.6 0.0 15.2 4.5 15.7 84.9 0.9 48.7 0.0 0.0 0.1 6.1 41.3 28.8 24.8 50.7 30.4 12.4 5.6 10.2 14.1 4.1 0.0 0.1 28.9 1.1 48.5 7.9 56.6 0.4 7.7 5.6 0.9 26.3 7.8 98.4 8.4 3.3 0.7 12.4 161.3 9.7 58.2 0.5 30.3 EVX1 ENSG00000106038 "Even-skipped homeobox 1" P49640 7 27242700-27250493 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.9;prostate: 3.8;seminal vesicle: 2.9;urinary bladder: 3.3;vagina: 3.5" "Group enriched" "Detected in some" 33 "Early spermatids: 62.0;Late spermatids: 73.3" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.6" "Region enhanced" "Detected in single" "medulla oblongata: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "OE19: 25.2;RT4: 16.1" "Region enhanced" "Detected in single" "pons and medulla: 1.0" "Not detected" "Not detected" HPA055132 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA055132: AB_2682707" "unprognostic (2.73e-2)" "unprognostic (3.59e-1)" "unprognostic (4.31e-1)" "unprognostic (5.16e-2)" "unprognostic (1.76e-3)" "unprognostic (2.08e-2)" "unprognostic (8.48e-3)" "unprognostic (5.94e-2)" "unprognostic (1.26e-8)" "unprognostic (2.94e-1)" "unprognostic (1.39e-1)" "unprognostic (9.12e-2)" "unprognostic (1.83e-2)" 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.8 0.0 0.0 0.0 0.0 0.1 0.9 3.8 0.3 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 3.3 3.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 0.2 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.8 0.9 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 62.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 73.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.1 2.0 EXD3 "FLJ20433, LOC54932, mut-7, Nbr" ENSG00000187609 "Exonuclease 3'-5' domain containing 3" Q8N9H8 9 137306896-137423211 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 73.2;Paneth cells: 178.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.4" "Low region specificity" "Detected in all" HPA047395 Approved Approved "Actin filaments,Focal adhesion sites" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Focal adhesion sites" "Actin filaments" "HPA047395: AB_10962864" "unprognostic (2.91e-1)" "unprognostic (5.67e-2)" "unprognostic (1.75e-3)" "prognostic favorable (4.30e-4)" "unprognostic (1.88e-1)" "unprognostic (1.70e-1)" "unprognostic (6.65e-2)" "unprognostic (1.37e-1)" "unprognostic (2.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.50e-3)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "unprognostic (7.99e-3)" "unprognostic (2.05e-1)" "unprognostic (8.67e-2)" "unprognostic (5.05e-2)" 9.4 10.1 6.2 3.5 6.8 3.5 10.8 5.9 11.0 11.5 6.6 16.0 9.4 9.9 1.5 11.6 12.3 4.2 11.2 6.5 5.8 12.2 8.1 10.2 3.8 7.2 6.1 10.7 9.8 3.7 13.5 3.4 6.4 14.5 3.6 0.8 10.1 3.7 9.5 10.2 11.3 1.4 5.5 14.8 12.3 4.8 6.1 1.1 11.4 2.6 2.3 10.9 11.2 6.3 8.3 7.0 3.3 9.5 2.8 4.0 7.8 4.0 4.5 3.5 5.3 4.8 17.5 3.5 9.1 3.1 8.7 14.5 1.0 4.4 1.1 8.2 8.1 2.6 13.0 7.9 8.5 1.9 29.4 4.8 6.0 3.1 2.8 10.2 11.9 0.0 7.0 6.4 3.0 22.3 0.1 6.9 3.8 18.1 4.7 6.3 2.6 25.3 7.1 4.7 4.5 7.7 4.0 8.4 3.8 3.8 13.6 9.3 15.0 4.8 4.4 7.5 6.2 8.1 4.1 3.0 8.7 6.4 7.4 10.7 3.4 7.8 2.2 4.5 2.7 2.6 4.0 2.1 3.9 2.4 3.1 2.5 0.8 4.1 4.4 2.5 6.1 2.3 6.2 6.8 5.9 11.0 6.5 5.8 7.2 6.1 6.4 5.5 6.1 6.3 17.6 0.0 6.3 24.2 5.3 5.9 10.0 8.9 13.6 14.6 13.5 17.0 5.2 10.0 11.2 7.3 14.6 9.9 8.1 46.4 9.8 6.8 17.9 11.5 6.5 14.1 7.3 5.0 21.6 11.3 3.3 7.3 19.4 13.1 61.7 10.5 17.2 7.2 9.2 21.9 24.1 27.6 16.2 5.4 7.3 73.2 5.9 6.9 3.6 13.1 6.2 10.0 12.3 26.2 14.6 6.4 178.2 7.9 6.6 10.0 31.3 11.9 9.3 10.4 13.1 5.5 9.9 2.3 8.9 9.9 8.9 4.0 6.4 19.5 39.0 9.2 EXOG "ENDOGL1, ENDOGL2, ENGL, ENGL-a, ENGL-b" ENSG00000157036 "Exo/endonuclease G" Q9Y2C4 3 38496127-38542161 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 59.8;Rod photoreceptor cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012531, HPA071050" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA012531: AB_2732403, HPA071050: " "unprognostic (2.88e-1)" "unprognostic (5.81e-3)" "unprognostic (3.55e-3)" "unprognostic (2.77e-1)" "unprognostic (8.32e-3)" "unprognostic (8.90e-3)" "unprognostic (4.78e-4)" "unprognostic (3.59e-2)" "unprognostic (3.99e-2)" "unprognostic (3.10e-2)" "prognostic favorable (1.92e-5)" "prognostic unfavorable (4.90e-4)" "unprognostic (6.51e-2)" "unprognostic (1.64e-2)" "unprognostic (4.79e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" 3.9 5.1 5.5 4.0 5.4 3.9 3.4 7.9 7.0 5.2 3.4 4.9 2.0 4.7 3.5 2.6 3.8 3.5 12.9 5.9 5.1 3.7 3.4 3.8 6.0 5.1 5.7 3.9 3.9 3.3 5.6 2.9 4.5 4.8 3.2 5.3 3.2 3.6 3.2 1.9 4.4 4.5 4.1 5.5 3.6 3.9 5.9 5.0 4.5 3.2 4.7 4.4 3.5 6.4 4.3 7.6 8.7 7.6 5.7 8.4 3.5 13.9 8.7 11.6 12.9 6.8 4.3 15.1 3.5 5.5 3.3 4.3 11.0 4.7 9.8 17.5 10.2 11.4 12.7 7.6 7.0 12.7 9.5 6.4 5.2 10.3 5.4 5.5 16.2 8.6 5.2 9.9 18.2 2.9 8.6 4.2 8.3 3.7 9.8 5.8 4.6 6.7 6.0 5.5 4.0 2.0 8.5 2.1 3.8 3.9 2.9 6.1 13.3 9.5 7.2 10.8 11.2 5.7 10.3 13.3 7.4 10.9 7.1 0.9 10.0 4.5 26.6 9.8 23.8 60.3 25.8 26.4 7.2 47.1 25.9 25.2 0.6 27.8 11.6 14.4 12.9 5.5 5.5 5.4 7.9 7.0 5.9 5.1 5.1 5.7 4.5 4.1 5.9 6.4 9.8 6.4 4.5 15.3 24.9 2.9 6.5 13.4 8.0 49.9 4.4 3.7 33.0 7.2 5.8 11.0 56.3 12.3 23.8 5.4 0.0 8.5 3.7 3.2 9.7 12.9 16.9 13.7 23.5 5.3 2.1 10.8 4.6 3.6 1.3 14.0 9.7 5.7 7.0 40.4 29.1 7.5 10.2 8.3 6.2 3.7 27.1 6.0 12.4 15.0 16.0 13.0 59.8 31.7 23.5 6.4 7.4 17.7 19.1 5.5 4.3 4.0 8.0 78.3 13.1 11.6 9.5 36.5 28.0 4.6 1.0 1.9 22.9 14.0 9.7 6.3 EXTL1 "EXTL, MGC70794" ENSG00000158008 "Exostosin like glycosyltransferase 1" Q92935 1 26019884-26036464 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 14.2;skeletal muscle: 12.7;tongue: 29.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.3;Breast glandular cells: 8.8;Excitatory neurons: 22.7;Horizontal cells: 10.1;Melanocytes: 7.2;Oligodendrocyte precursor cells: 10.6" "Cancer enriched" "Detected in some" 13 "melanoma: 21.7" "Group enriched" "Detected in many" 11 "amygdala: 10.3;basal ganglia: 9.8;cerebral cortex: 14.2;hippocampal formation: 11.5;white matter: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 150.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010726, HPA037749" Uncertain Approved Vesicles,Centrosome "Intracellular and membrane" NA NA 79000 "Cluster 47: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" Centrosome Vesicles "HPA010726: , HPA037749: AB_10805350" "unprognostic (2.00e-1)" "unprognostic (1.10e-2)" "unprognostic (8.16e-3)" "unprognostic (1.47e-2)" "unprognostic (2.47e-2)" "unprognostic (6.14e-3)" "unprognostic (3.78e-2)" "unprognostic (1.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (1.44e-2)" "unprognostic (3.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-3)" "unprognostic (2.27e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-2)" 0.2 1.0 10.3 0.0 9.8 0.0 0.8 0.0 14.2 0.4 0.0 1.0 0.1 3.6 0.1 0.5 0.7 0.3 3.5 11.5 0.0 0.4 0.0 0.2 0.2 0.1 0.6 1.1 1.5 0.0 0.9 0.3 0.4 0.4 0.0 0.8 0.5 0.2 12.7 2.3 0.3 1.3 0.0 3.5 0.3 0.6 0.9 0.0 0.2 29.8 0.0 0.3 0.4 6.9 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.7 0.0 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.2 0.6 0.0 0.2 2.4 0.2 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 150.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 9.8 0.0 14.2 11.5 0.0 0.1 0.6 0.4 0.0 0.9 6.9 0.1 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 15.3 8.8 1.8 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 22.7 0.0 0.0 0.4 0.0 0.2 0.0 0.4 0.0 0.0 0.1 10.1 5.1 0.0 0.0 0.0 0.3 0.6 1.5 0.0 7.2 2.8 0.0 0.4 0.0 10.6 1.9 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.4 0.4 0.2 0.2 0.0 0.0 1.0 0.0 1.1 0.1 0.1 EXTL2 ENSG00000162694 "Exostosin like glycosyltransferase 2" Q9UBQ6 1 100872372-100895179 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 214.1;Theca cells: 328.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020716, HPA068921" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 80000000 "Cluster 40: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "CAB020716: , HPA068921: AB_2686058" "unprognostic (3.14e-1)" "unprognostic (6.34e-2)" "unprognostic (1.50e-2)" "unprognostic (8.20e-2)" "unprognostic (9.07e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (7.81e-3)" "unprognostic (1.10e-2)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" "unprognostic (3.00e-1)" "unprognostic (3.17e-2)" "unprognostic (6.84e-2)" "unprognostic (7.83e-2)" "unprognostic (1.24e-2)" "unprognostic (4.34e-2)" 8.8 24.6 11.4 5.0 15.0 2.2 11.5 12.0 16.4 13.9 19.1 10.8 4.8 18.1 13.7 6.5 10.9 11.4 9.2 10.3 15.4 12.9 12.6 8.4 4.2 12.9 14.9 19.6 9.0 14.6 12.9 24.9 13.7 13.4 7.6 13.9 7.1 11.9 6.9 6.5 5.4 17.0 11.2 6.5 7.3 10.7 17.8 8.2 10.1 7.1 3.7 9.2 6.9 11.3 13.0 6.9 50.2 50.7 53.2 39.3 31.4 23.2 37.5 17.5 39.4 6.1 9.9 15.2 21.8 20.9 13.5 12.7 18.3 19.6 35.4 31.8 13.4 19.0 23.6 18.3 17.5 28.9 9.3 47.3 6.8 35.9 6.6 36.5 65.0 19.2 23.9 2.0 45.1 6.9 15.5 15.5 62.2 12.2 15.5 11.2 51.5 12.1 18.4 9.7 20.6 57.5 17.4 4.6 42.0 35.8 10.9 12.7 27.7 44.0 25.8 27.8 24.4 15.5 15.0 9.8 69.2 29.3 14.4 2.0 0.5 0.0 3.4 0.7 1.5 1.2 1.1 2.3 1.7 1.7 1.2 2.7 0.1 3.9 0.5 4.6 0.0 1.2 11.4 15.0 12.0 16.4 10.3 15.4 12.9 14.9 13.7 11.2 17.8 11.3 12.3 12.8 8.4 39.8 4.9 8.5 10.2 13.8 21.1 20.7 13.2 13.5 12.7 10.0 11.0 14.7 35.5 214.1 5.0 3.3 11.7 5.8 45.3 20.3 28.7 13.1 9.5 16.2 47.1 2.1 36.9 36.0 15.3 11.0 17.7 35.3 13.6 16.4 24.3 3.3 49.9 5.6 12.2 7.3 5.7 34.9 25.1 5.8 23.2 12.2 7.4 18.8 8.2 40.7 32.9 2.4 2.6 34.6 5.9 6.2 2.9 11.9 25.3 19.7 13.1 25.4 22.4 37.1 12.3 8.5 8.1 74.3 6.1 328.5 7.1 4.9 EYS "bA166P24.2, bA307F22.3, bA74E24.1, C6orf178, C6orf179, C6orf180, dJ1018A4.2, dJ303F19.1, EGFL10, EGFL11, RP25, SPAM" ENSG00000188107 "Eyes shut homolog" Q5T1H1 6 63719980-65707226 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "retina: 24.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 316.9;Early spermatids: 87.3;Inhibitory neurons: 83.8;Late spermatids: 45.7;Rod photoreceptor cells: 140.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "Karpas-707: 1.5;SCLC-21H: 1.1" "Secreted in other tissues" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (2.92e-2)" "unprognostic (1.90e-2)" "unprognostic (1.64e-1)" "unprognostic (1.47e-2)" "unprognostic (2.16e-3)" "unprognostic (1.96e-1)" "unprognostic (1.82e-1)" "unprognostic (6.38e-2)" "unprognostic (3.67e-1)" "unprognostic (1.97e-1)" "unprognostic (2.04e-1)" "unprognostic (2.18e-1)" "unprognostic (2.61e-4)" "unprognostic (1.89e-1)" "unprognostic (8.41e-2)" "unprognostic (6.38e-3)" "unprognostic (1.11e-1)" 0.6 0.0 0.3 0.0 0.4 0.3 0.2 0.6 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.1 0.0 0.1 0.0 0.1 0.1 0.5 0.1 0.6 24.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 1.5 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.3 0.3 0.4 0.6 0.6 0.4 0.0 0.4 0.1 0.5 0.0 0.1 0.3 0.1 0.0 1.8 3.9 0.5 0.3 0.7 0.1 0.6 8.3 0.1 0.0 2.1 0.0 0.7 1.8 316.9 0.8 0.2 0.0 0.0 0.4 87.3 1.0 1.0 0.7 20.3 0.0 22.0 0.4 0.4 0.7 0.0 2.1 2.5 0.0 0.0 0.3 0.1 10.1 83.8 0.4 0.0 0.0 0.6 45.7 0.9 0.2 0.0 3.7 0.1 4.0 0.0 5.5 12.9 0.3 0.0 0.7 0.1 0.2 0.1 0.3 0.1 140.2 0.0 1.5 0.3 2.6 1.3 0.4 0.1 1.1 0.6 0.3 0.2 0.2 F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 113.6;Hepatocytes: 195.1;Leydig cells: 215.9;Peritubular cells: 236.2" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 14.4;BJ hTERT+: 11.5;CACO-2: 12.7;fHDF/TERT166: 13.1;Hep G2: 59.6;HHSteC: 11.5;SH-SY5Y: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" 21.3 8.5 1.1 1.5 1.2 0.0 11.7 2.5 2.0 53.8 1.4 5.6 10.9 13.2 16.4 8.9 23.9 10.9 40.7 1.1 1.8 4.1 160.0 14.4 3.2 2.6 1.5 27.9 7.1 0.2 4.5 4.4 2.5 12.8 2.0 0.9 5.1 7.1 6.8 20.7 11.9 2.7 1.3 3.2 8.6 10.1 1.4 1.4 8.3 6.6 1.3 11.9 25.8 1.1 0.1 0.0 2.5 0.4 8.0 8.1 0.1 14.4 11.5 0.8 0.3 12.7 0.1 0.1 0.5 13.1 1.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 59.6 11.5 0.0 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 1.5 0.1 0.0 0.3 0.0 1.3 0.2 0.3 0.1 0.0 0.0 0.2 1.0 27.9 0.1 0.5 0.1 0.6 0.6 0.1 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 2.5 2.0 1.1 1.8 2.6 1.5 2.5 1.3 1.4 1.1 7.0 0.0 0.0 1.3 0.6 15.7 0.1 0.0 0.0 1.1 0.4 0.3 9.1 4.3 0.0 1.8 0.0 0.6 0.0 0.1 0.0 0.1 2.9 1.9 45.9 3.8 17.9 2.7 1.3 0.0 0.4 113.6 6.1 1.0 1.3 2.2 7.9 195.1 1.4 6.7 1.4 5.0 0.0 4.8 25.0 9.6 215.9 1.3 19.6 5.6 0.6 4.5 0.0 0.5 0.1 0.3 6.5 236.2 0.0 0.3 28.3 6.4 0.0 1.2 52.6 14.5 40.9 2.3 1.2 0.5 15.3 1.1 1.9 2.4 2.2 0.4 F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186266189-186289681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 243.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 27.6;Hepatocytes: 75.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "Hep G2: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039808 Approved Vesicles "Secreted to blood" NA NA 4400000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA039808: AB_2676693" "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.2 17.1 0.2 0.1 0.0 0.0 13.1 0.0 0.2 0.0 27.6 243.2 8.4 0.0 0.0 0.3 0.3 58.9 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.0 0.2 0.7 0.0 8.7 0.0 0.0 0.1 0.8 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.2 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 27.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.3 2.5 1.8 0.0 0.0 0.2 0.3 11.7 2.3 0.0 0.0 0.0 0.1 0.0 5.3 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.7 0.0 0.0 0.6 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 1.1 5.5 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 F12 ENSG00000131187 "Coagulation factor XII" P00748 5 177402141-177409564 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 226 "liver: 604.6" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 523.0" "Cancer enriched" "Detected in many" 21 "liver cancer: 171.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "classical monocyte: 1.2;eosinophil: 3.6" "Group enriched" "Detected in many" 5 "granulocytes: 3.6;monocytes: 1.2" "Cell line enhanced" "Detected in some" "HDLM-2: 7.1;MCF7: 9.0;PC-3: 6.4;SH-SY5Y: 4.3;U-937: 4.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA003825 Approved "Secreted to blood" NA NA 1040000 7000000000 "Cluster 52: Eosinophils - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" "HPA003825: AB_1078790" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (2.93e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "prognostic favorable (4.63e-5)" "unprognostic (6.97e-2)" "unprognostic (1.26e-2)" "unprognostic (3.96e-2)" "unprognostic (4.41e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (4.11e-2)" "unprognostic (3.69e-1)" "unprognostic (3.40e-6)" "unprognostic (6.48e-2)" 0.4 0.1 1.4 0.1 1.2 2.6 0.3 0.1 1.3 0.4 0.1 0.5 0.5 0.2 0.0 1.9 0.3 0.1 0.4 1.5 0.8 0.8 604.6 0.6 0.0 0.8 0.6 0.0 0.6 0.1 0.6 0.1 0.9 0.3 0.1 0.0 0.4 0.0 0.0 0.9 0.5 0.0 0.4 1.0 0.1 1.2 0.8 0.0 0.2 0.0 0.1 0.2 0.8 0.8 0.7 1.6 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 1.0 0.0 0.3 0.0 0.2 1.1 0.5 0.3 0.0 7.1 1.4 1.1 0.3 0.7 0.2 0.6 2.4 0.2 1.0 0.0 0.3 0.1 0.2 1.6 0.3 2.5 0.0 9.0 0.1 2.1 0.0 2.1 6.4 0.5 0.2 1.5 0.9 0.0 2.0 4.3 0.2 0.7 0.6 0.0 0.3 0.0 0.0 0.1 0.8 0.0 0.2 0.4 0.0 0.0 0.0 4.6 0.5 0.0 1.2 3.6 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.5 0.5 0.0 0.5 1.4 1.2 0.1 1.3 1.5 0.8 0.8 0.6 0.9 0.4 0.8 0.8 0.5 0.0 0.0 0.3 5.3 33.1 7.7 15.3 35.9 0.6 12.7 17.5 1.0 17.2 3.9 1.8 4.2 0.0 4.0 27.6 0.0 6.5 23.3 2.2 0.9 2.2 10.3 19.6 2.6 4.2 0.4 1.1 3.6 1.7 0.0 0.2 16.8 523.0 0.5 0.0 0.8 12.3 8.2 16.7 6.1 42.1 0.6 1.0 8.8 0.0 1.2 0.7 2.1 1.5 0.6 11.1 22.0 0.0 8.5 7.2 60.7 16.1 3.6 0.9 0.0 0.5 1.1 12.0 23.6 57.5 54.3 0.1 4.0 0.1 34.8 7.6 F13B FXIIIB ENSG00000143278 "Coagulation factor XIII B chain" P05160 1 197038741-197067260 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 211 "liver: 200.2" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 54.9" "Cancer enriched" "Detected in single" 816 "liver cancer: 46.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003827, HPA052139" Supported "Secreted to blood" NA NA 4700000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "HPA003827: AB_1078794, HPA052139: AB_2681744" "unprognostic (1.46e-1)" "prognostic favorable (6.78e-5)" "unprognostic (1.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 200.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 54.9 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 F2 ENSG00000180210 "Coagulation factor II, thrombin" P00734 11 46719196-46739506 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1518 "liver: 1217.3" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 991.0" "Cancer enriched" "Detected in some" 110 "liver cancer: 508.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "Hep G2: 281.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016780, HPA051476, HPA054698" Enhanced "Secreted to blood" NA NA 108000000000 41000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016780: , HPA051476: AB_2681498, HPA054698: AB_2682578" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-1)" "unprognostic (2.23e-2)" "unprognostic (3.94e-2)" "unprognostic (5.79e-2)" "unprognostic (8.29e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.75e-12)" "unprognostic (5.65e-3)" "unprognostic (5.80e-2)" "unprognostic (1.54e-3)" 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.2 1217.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.9 0.0 0.2 2.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.2 281.0 0.0 1.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.3 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.2 0.0 37.5 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 21.8 991.0 0.0 0.0 0.2 0.2 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.0 0.0 0.0 0.1 F2R "CF2R, PAR-1, PAR1, TR" ENSG00000181104 "Coagulation factor II thrombin receptor" P25116 5 76716126-76735770 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 69.5" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 307.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 25.4" "Group enriched" "Detected in many" 14 "NK-cells: 7.0;T-cells: 25.4" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 196.9;HUVEC TERT2: 366.2;WM-115: 345.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008973, CAB012962" Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB008973: , CAB012962: AB_2533198" "unprognostic (3.03e-1)" "unprognostic (7.76e-2)" "unprognostic (5.55e-2)" "unprognostic (7.76e-2)" "unprognostic (7.14e-2)" "unprognostic (3.46e-1)" "unprognostic (2.51e-1)" "unprognostic (3.75e-2)" "unprognostic (5.37e-2)" "unprognostic (1.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (2.21e-7)" "unprognostic (2.72e-3)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (6.74e-3)" 14.5 13.5 1.2 12.1 1.4 4.0 18.3 1.6 1.5 15.4 1.6 10.0 14.2 23.2 4.2 11.1 3.9 39.5 30.4 1.2 1.5 19.1 23.9 22.8 16.2 2.5 2.6 2.9 9.9 7.3 4.3 10.5 2.1 7.2 11.6 0.7 30.5 12.0 3.6 45.7 18.8 18.8 1.8 69.5 10.3 8.8 1.9 4.9 15.2 11.9 8.6 15.4 4.5 1.5 5.7 17.5 53.3 8.8 98.4 170.5 2.6 30.3 102.5 19.5 69.8 3.9 47.0 0.1 50.1 13.0 88.1 13.2 23.1 18.1 36.6 4.4 19.3 120.2 3.8 14.7 147.7 0.6 4.9 96.9 60.2 37.2 10.5 196.9 366.2 21.4 22.8 22.1 40.1 2.4 9.6 0.4 17.0 0.3 93.5 17.1 31.9 4.3 91.2 0.8 6.3 28.7 8.9 0.2 45.2 48.0 0.7 1.3 169.0 121.8 26.7 1.3 56.7 59.0 18.5 0.2 32.4 2.3 345.5 1.1 0.2 0.4 25.4 0.5 6.5 0.6 5.7 17.7 0.0 0.2 0.9 12.7 1.1 7.0 0.1 0.3 0.6 11.2 1.2 1.4 1.6 1.5 1.2 1.5 2.5 2.6 2.1 1.8 1.9 1.5 25.8 0.0 9.2 1.6 4.4 17.2 0.7 9.3 1.2 3.5 3.4 2.4 2.6 7.2 4.5 7.3 0.0 0.2 56.2 0.3 0.0 2.0 10.7 2.8 47.1 51.8 6.6 11.6 1.0 2.2 0.4 39.5 8.2 5.4 6.3 13.0 307.0 4.3 2.1 0.0 3.3 3.9 16.2 16.6 10.7 6.0 0.9 5.4 12.4 5.6 1.1 0.1 54.6 0.5 0.1 10.8 0.2 10.5 35.8 1.4 0.5 3.4 4.2 1.4 0.0 8.1 24.9 12.7 5.4 1.5 40.1 0.3 40.1 9.5 1.3 0.4 F2RL3 PAR4 ENSG00000127533 "F2R like thrombin or trypsin receptor 3" Q96RI0 19 16888999-16892606 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 19.0;lung: 33.4;thyroid gland: 19.2" "Cell type enriched" "Detected in some" 4 "Adipocytes: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "HEL: 30.7;HMC-1: 11.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031401, HPA042340" Supported "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "HPA031401: , HPA042340: " "unprognostic (6.17e-2)" "unprognostic (1.08e-1)" "unprognostic (2.64e-2)" "unprognostic (3.83e-1)" "unprognostic (3.27e-1)" "unprognostic (8.31e-3)" "unprognostic (2.97e-1)" "unprognostic (3.28e-2)" "unprognostic (6.52e-2)" "unprognostic (2.60e-1)" "unprognostic (6.30e-2)" "unprognostic (3.00e-3)" "prognostic favorable (6.25e-4)" "unprognostic (2.37e-2)" "unprognostic (1.43e-1)" "unprognostic (3.53e-1)" "unprognostic (2.11e-2)" 19.0 2.6 0.7 1.5 0.7 1.3 18.0 1.9 0.7 1.1 1.2 4.3 1.5 1.6 1.6 1.5 1.5 2.8 5.6 0.6 0.7 9.8 0.5 33.4 2.3 0.5 0.6 0.8 9.3 1.1 2.7 1.0 0.5 1.4 1.3 1.2 1.2 0.5 3.2 3.1 4.9 1.0 0.0 1.3 5.0 1.7 1.2 0.4 19.2 0.6 0.9 1.9 1.2 1.3 0.3 0.3 0.8 0.4 0.1 0.2 0.9 0.4 0.1 0.2 0.2 0.5 0.8 0.6 0.6 0.3 0.3 0.6 0.2 0.3 0.3 0.4 0.4 30.7 1.3 0.5 0.2 0.3 11.6 0.0 0.1 0.3 0.2 0.4 0.9 0.6 2.5 1.1 0.2 0.5 0.4 2.9 0.4 0.4 0.3 0.3 0.2 1.0 0.3 0.6 0.5 0.3 0.3 0.2 0.1 0.7 0.6 2.0 1.2 0.6 0.6 0.4 0.3 0.5 0.4 0.6 0.3 0.5 0.4 3.3 0.9 0.7 0.9 0.4 0.8 1.6 1.0 0.8 0.3 1.8 1.4 1.3 2.2 1.8 0.6 1.7 0.8 1.4 0.7 0.7 1.9 0.7 0.6 0.7 0.5 0.6 0.5 0.0 1.2 1.3 110.4 0.0 1.1 0.0 0.3 0.4 0.3 0.3 0.0 0.0 0.3 0.3 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.9 27.5 0.0 0.8 0.0 0.5 0.0 2.7 0.0 0.2 7.0 0.3 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.3 1.0 0.4 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.0 0.6 0.0 0.1 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.1 0.4 0.5 0.1 0.3 0.2 0.3 F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 902.0;Exocrine glandular cells: 464.1;Pancreatic endocrine cells: 1755.7;Peritubular cells: 530.7;Urothelial cells: 497.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 1062.0;HaCaT: 490.7;HBEC3-KT: 1270.5;U-2197: 473.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" NA NA 603000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB009438: AB_668005, HPA049292: AB_2680701, HPA069132: AB_2686092" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (8.04e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.93e-2)" "unprognostic (8.00e-2)" "unprognostic (5.88e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.02e-8)" "unprognostic (4.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" 118.2 21.3 53.1 28.8 69.9 4.1 70.1 53.2 74.4 48.0 44.1 52.2 36.8 61.1 44.2 41.3 89.9 59.6 36.8 54.0 62.7 18.0 5.1 59.8 12.9 77.7 62.6 114.8 96.5 17.2 81.2 133.4 57.1 56.8 42.1 72.6 93.3 60.4 7.6 56.0 47.3 10.7 60.8 7.2 42.6 34.6 62.0 5.6 62.6 9.9 14.9 65.4 73.0 55.4 1062.0 1.8 2.2 0.5 108.0 53.1 57.2 147.0 87.6 155.4 167.9 18.6 220.6 0.0 73.3 183.5 33.4 490.7 13.2 1270.5 254.4 0.9 1.6 0.0 35.0 3.3 35.9 0.7 0.6 91.9 28.2 73.8 356.5 293.7 1.1 1.1 0.9 0.8 110.0 1.8 1.5 22.3 9.8 6.8 2.2 1.2 10.3 0.5 19.8 3.2 1.3 2.6 117.4 48.3 3.6 29.6 1.3 13.9 0.3 93.7 2.5 473.0 44.6 0.9 1.3 0.9 71.9 5.7 3.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 53.1 69.9 53.2 74.4 54.0 62.7 77.7 62.6 57.1 60.8 62.0 55.4 9.4 131.4 243.3 196.6 0.7 16.3 902.0 359.6 2.2 3.6 29.6 20.4 26.4 18.6 380.3 14.7 0.0 16.5 0.6 20.9 0.0 133.5 8.6 61.3 125.0 13.2 13.1 0.0 0.4 464.1 6.0 125.3 23.0 123.0 2.5 38.1 7.5 0.4 6.1 3.3 4.6 70.3 65.1 2.8 5.2 14.5 281.1 9.1 3.6 45.9 2.1 340.6 0.0 15.6 1.2 1755.7 15.5 530.7 1.2 121.6 10.1 0.4 92.0 16.1 6.6 39.3 76.7 1.7 4.4 6.4 7.5 7.7 7.3 7.9 14.3 497.9 F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 142.8;liver: 176.2;placenta: 46.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Cytotrophoblasts: 82.7;Hepatocytes: 253.4;Syncytiotrophoblasts: 59.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 69.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Group enriched" "Detected in some" 23 "Hep G2: 32.8;OE19: 125.5" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.4" "Group enriched" "Detected in all" 7 "amygdala: 39.9;basal ganglia: 35.0;cerebral cortex: 67.9;hippocampal formation: 61.4;olfactory bulb: 27.6" HPA002036 Approved "Golgi apparatus" "Secreted to blood" NA NA 7670000000 13000000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA002036: AB_1078787" "unprognostic (3.67e-2)" "unprognostic (2.77e-4)" "unprognostic (5.42e-2)" "unprognostic (2.56e-4)" "unprognostic (2.03e-1)" "unprognostic (2.39e-4)" "unprognostic (3.46e-3)" "unprognostic (9.25e-3)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.15e-2)" "unprognostic (3.41e-1)" "unprognostic (4.31e-1)" 1.1 0.0 0.3 3.2 1.4 3.7 0.6 4.4 1.3 0.1 142.8 0.3 0.9 0.1 0.2 0.2 3.5 17.6 2.7 4.4 1.6 1.5 176.2 0.9 2.2 1.9 2.2 0.0 0.8 0.0 1.6 46.9 2.4 1.3 0.6 1.0 6.2 0.0 0.2 1.3 0.3 1.1 0.8 1.8 4.9 0.5 2.2 0.5 0.4 0.2 2.3 3.8 0.1 4.2 0.0 0.6 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 32.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 125.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.1 8.1 0.0 0.2 0.0 0.0 1.4 0.2 0.4 0.0 0.3 0.0 7.0 0.0 0.0 0.0 6.2 1.1 0.3 1.4 4.4 1.3 4.4 1.6 1.9 2.2 2.4 0.8 2.2 4.2 0.0 3.2 0.6 1.6 0.7 0.1 6.1 0.0 0.0 0.3 0.7 0.3 9.4 74.4 1.9 0.0 2.1 82.7 0.1 0.3 0.0 2.4 2.4 0.9 0.0 2.4 25.2 0.0 5.4 0.2 2.3 5.3 4.1 0.2 0.0 2.8 3.6 253.4 5.3 0.0 2.6 0.1 0.0 12.3 0.4 0.3 0.0 7.1 3.6 0.0 18.2 1.0 2.1 0.5 1.0 1.9 0.0 0.0 0.1 1.8 0.0 0.2 3.1 0.1 0.0 2.4 0.2 0.5 0.5 0.0 0.0 59.5 2.5 0.0 0.0 11.8 F7 ENSG00000057593 "Coagulation factor VII" P08709 13 113105788-113120685 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "liver: 160.2" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 149.3" "Cancer enriched" "Detected in some" 17 "liver cancer: 41.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "CACO-2: 11.5;Hep G2: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA004826 Approved Mitochondria "Secreted to blood" NA NA 351000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA004826: AB_10602805" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-3)" "unprognostic (3.81e-1)" "unprognostic (4.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.35e-3)" "unprognostic (3.36e-3)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" 0.2 0.0 0.4 0.1 0.3 0.0 0.2 0.5 0.7 1.1 0.2 0.1 0.5 0.1 0.6 0.1 0.5 0.0 0.2 0.3 0.7 0.4 160.2 0.1 0.0 0.3 0.5 0.4 0.1 0.2 0.4 0.1 0.3 0.4 0.0 0.2 0.3 0.0 0.0 0.4 0.8 0.0 0.2 0.1 0.1 1.5 0.6 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.5 0.7 0.3 0.7 0.3 0.5 0.3 0.2 0.6 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.6 0.3 0.5 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.0 8.0 0.3 0.2 0.0 0.4 0.0 0.2 0.0 0.3 2.2 149.3 0.1 0.0 0.5 0.4 0.0 2.8 0.7 0.2 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 1.1 0.3 0.0 0.2 0.0 0.5 0.1 3.2 4.1 0.0 0.1 0.1 0.2 0.1 0.3 0.0 F8 "DXS1253E, F8C, FVIII, HEMA" ENSG00000185010 "Coagulation factor VIII" P00451 X 154835788-155026940 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Hemophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 53.2" "Group enriched" "Detected in many" 10 "Adipocytes: 118.6;Endothelial cells: 120.4;Hepatic stellate cells: 371.2" "Cancer enhanced" "Detected in all" "renal cancer: 7.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 16.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB018777 Enhanced "Secreted to blood" NA NA 25000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB018777: AB_640320" "unprognostic (2.09e-1)" "unprognostic (5.66e-4)" "unprognostic (4.94e-2)" "unprognostic (8.32e-5)" "unprognostic (1.26e-1)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" "unprognostic (8.27e-2)" "unprognostic (6.58e-2)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "unprognostic (5.58e-2)" "unprognostic (1.24e-2)" "unprognostic (2.16e-3)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (4.44e-2)" 29.4 15.2 7.8 2.5 8.6 2.1 19.3 7.4 11.2 7.5 9.9 9.6 2.9 10.9 9.1 4.0 7.9 5.0 53.2 8.2 8.5 14.1 20.1 16.7 4.7 8.6 8.4 14.5 11.6 5.6 6.4 3.3 8.6 9.0 3.8 6.2 4.7 7.5 20.6 3.6 5.0 6.3 7.8 17.9 5.7 6.1 8.9 3.2 10.9 28.1 3.7 8.1 3.7 7.8 6.1 4.5 0.9 2.1 6.5 10.1 0.7 2.9 1.8 2.0 3.4 0.3 6.8 12.0 9.5 3.0 4.7 0.8 1.0 1.0 1.8 5.1 1.9 2.4 2.8 0.2 3.0 2.1 5.6 7.2 0.6 1.8 2.4 3.5 1.2 5.7 1.1 9.0 10.0 2.7 1.7 1.9 1.6 1.8 4.5 1.4 1.5 1.8 1.8 1.3 3.7 2.8 7.0 0.8 3.9 1.0 2.1 4.9 1.5 10.3 5.5 16.6 3.7 5.3 5.1 6.0 9.4 12.3 5.5 4.6 2.8 0.9 5.2 2.4 10.3 2.1 3.1 5.5 2.7 1.9 1.6 4.1 4.4 3.3 2.4 0.4 4.6 2.7 7.8 8.6 7.4 11.2 8.2 8.5 8.6 8.4 8.6 7.8 8.9 7.8 118.6 0.0 6.3 13.1 2.3 1.8 2.5 1.6 4.0 8.1 3.7 4.2 17.7 7.2 1.9 3.7 2.1 0.9 2.0 0.6 7.9 3.1 1.4 1.5 1.5 120.4 0.0 8.4 7.2 0.7 0.7 6.8 0.0 1.5 1.3 8.2 371.2 11.8 3.2 6.7 5.0 0.6 0.0 19.9 1.1 3.3 11.5 3.0 0.0 8.4 2.4 6.8 2.1 7.5 6.0 4.5 0.1 5.3 2.0 1.4 0.9 11.4 2.4 3.5 6.6 11.1 13.0 2.3 3.4 1.5 1.1 0.1 4.0 4.3 0.4 2.1 F9 FIX ENSG00000101981 "Coagulation factor IX" P00740 X 139530739-139563459 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets, Hemophilia, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2467 "liver: 704.9" "Cell type enriched" "Detected in some" 32 "Hepatocytes: 609.1" "Cancer enriched" "Detected in single" 1354 "liver cancer: 67.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 8200000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 15: Hepatocytes - Hemostasis" "prognostic favorable (6.69e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 704.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 609.1 0.0 0.0 0.1 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 FAAP24 "C19orf40, FLJ46828, MGC32020" ENSG00000131944 "FA core complex associated protein 24" Q9BTP7 19 32972209-32978229 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 14.6;Spermatocytes: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041168 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "HPA041168: AB_10960496" "unprognostic (1.18e-2)" "unprognostic (1.22e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (6.52e-2)" "unprognostic (2.73e-1)" "unprognostic (2.58e-3)" "unprognostic (3.76e-2)" "unprognostic (1.88e-2)" "unprognostic (3.98e-2)" "unprognostic (2.82e-3)" "unprognostic (3.54e-2)" "prognostic unfavorable (4.00e-7)" "unprognostic (4.37e-3)" "unprognostic (5.30e-1)" "unprognostic (2.31e-3)" "unprognostic (2.15e-1)" 1.7 1.4 0.8 2.6 0.7 3.5 1.8 1.2 1.1 1.0 1.1 1.7 1.8 1.3 2.4 1.8 1.4 2.3 0.7 0.8 0.6 1.2 1.4 1.4 3.1 1.4 0.6 2.5 0.9 0.4 0.8 1.6 1.0 4.8 2.5 0.5 1.2 1.1 0.5 2.8 2.2 1.5 0.4 2.4 1.4 6.2 0.9 2.6 1.8 0.2 3.5 1.5 1.2 2.2 6.0 15.0 5.7 9.3 3.2 6.3 4.9 7.7 8.2 14.5 18.8 10.3 9.7 7.0 11.2 3.2 11.4 4.2 11.7 5.9 11.5 19.4 5.4 15.3 5.8 7.6 1.7 5.2 7.5 3.5 3.5 9.0 5.3 2.3 5.9 11.2 8.2 7.1 11.1 6.7 11.6 7.1 2.6 8.7 6.7 10.2 5.1 3.9 2.9 3.6 5.9 4.9 8.7 9.9 6.1 6.2 6.6 13.7 3.5 14.2 6.6 6.2 7.2 5.5 12.4 9.6 10.1 11.9 9.6 15.3 5.7 8.8 3.2 6.9 3.8 6.4 4.0 4.9 3.6 6.2 3.6 5.2 13.9 7.1 7.8 6.9 5.6 3.2 0.8 0.7 1.2 1.1 0.8 0.6 1.4 0.6 1.0 0.4 0.9 2.2 1.7 3.2 1.1 0.0 3.0 0.0 3.3 0.0 1.8 1.5 3.9 3.6 0.5 2.8 1.3 3.7 2.1 11.1 6.5 1.2 1.9 1.6 7.2 4.4 3.0 2.1 1.2 7.4 0.0 8.0 14.6 3.1 0.5 6.3 1.3 7.1 3.6 0.4 8.2 5.0 0.0 2.4 0.0 5.1 0.0 12.3 3.4 3.5 0.0 0.0 7.0 0.6 2.1 0.0 0.0 4.2 2.4 3.4 2.6 3.2 3.5 1.0 0.0 1.0 0.0 2.7 2.2 22.6 8.3 2.7 0.0 5.1 2.5 5.8 2.7 2.6 FABP6 "I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP" ENSG00000170231 "Fatty acid binding protein 6" P51161 5 160187367-160238735 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 84 "intestine: 4531.3" "Cell type enriched" "Detected in some" 23 "Proximal enterocytes: 52213.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 31.6;EFO-21: 30.5;HDLM-2: 13.6;NB-4: 17.0;RPMI-8226: 17.2;RT4: 15.2;U-2197: 15.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA012601, CAB024713" Enhanced "Intracellular and membrane" NA NA 890000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "CAB024713: , HPA012601: AB_1848435" "unprognostic (3.03e-2)" "unprognostic (7.55e-2)" "unprognostic (1.27e-1)" "unprognostic (5.00e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (5.35e-7)" "unprognostic (3.05e-1)" "unprognostic (1.97e-1)" "unprognostic (2.41e-2)" "unprognostic (2.16e-1)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.35e-9)" "unprognostic (2.10e-2)" "unprognostic (1.21e-2)" "unprognostic (2.48e-1)" "unprognostic (1.85e-3)" 0.0 14.4 7.9 2.5 8.1 0.1 0.2 8.3 11.7 3.1 8.7 3.3 4.9 1.9 0.0 1.2 53.9 0.2 2.2 7.4 11.2 0.2 0.1 5.3 4.2 8.9 8.5 0.1 0.1 0.0 0.7 0.1 10.4 0.2 0.0 0.9 0.2 0.2 0.0 0.4 4531.3 3.4 9.4 1.5 0.4 3.1 9.4 5.6 0.1 1.4 3.5 2.7 0.4 7.7 0.3 0.6 0.0 0.2 0.0 0.0 11.4 0.0 0.0 0.0 0.0 8.1 1.3 31.6 30.5 0.0 0.3 0.0 0.0 0.0 0.0 13.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.5 0.0 0.0 2.3 1.2 0.4 0.0 0.0 0.0 17.0 0.1 0.0 2.9 0.0 1.0 17.2 0.0 15.2 2.8 0.7 0.0 8.8 0.2 0.1 0.2 0.2 0.0 0.0 0.1 15.3 1.7 1.7 6.9 4.0 0.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 8.1 8.3 11.7 7.4 11.2 8.9 8.5 10.4 9.4 9.4 7.7 0.0 0.0 1.5 1.3 0.2 0.5 0.3 7.8 0.6 0.2 0.1 0.1 3.4 0.0 21.9 0.0 0.0 0.0 0.0 0.6 0.0 0.9 0.4 110.2 0.6 0.1 0.0 0.0 1.6 0.0 0.3 0.6 0.0 1.4 0.0 0.6 0.0 0.0 0.1 1.7 2.2 2244.4 2.0 0.0 4.2 0.2 0.3 0.4 0.0 0.0 0.6 0.2 0.0 0.0 0.9 0.3 2080.0 0.0 0.0 0.1 52213.9 0.1 134.9 0.7 0.0 0.0 1.2 0.1 2.1 2.0 0.1 0.0 0.1 1.7 1304.0 1.4 FADS2 "D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13" ENSG00000134824 "Fatty acid desaturase 2" O95864 11 61792980-61867354 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 364.1" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Endometrial stromal cells: 57.7;Hepatocytes: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 1141.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006741 Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA006741: AB_1078796" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (8.34e-2)" "unprognostic (4.33e-3)" "unprognostic (4.63e-2)" "unprognostic (2.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.35e-3)" "unprognostic (2.01e-1)" "unprognostic (4.21e-2)" "unprognostic (8.95e-3)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.00e-7)" "unprognostic (6.19e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-2)" "prognostic unfavorable (3.42e-4)" 23.7 364.1 140.2 34.7 126.7 28.0 59.6 128.5 135.0 68.0 157.0 24.2 31.9 86.3 27.7 10.6 34.6 20.2 27.7 131.8 164.8 20.3 126.7 33.4 16.5 175.1 186.2 29.1 9.8 80.0 50.8 40.6 155.1 97.7 13.2 41.5 24.3 188.7 12.3 131.6 15.9 125.3 152.0 11.5 14.1 27.8 222.9 34.1 10.4 8.8 31.2 24.6 27.9 134.2 14.6 492.6 655.8 345.0 551.3 1141.8 167.2 86.3 658.3 109.0 288.2 31.4 149.6 3.8 11.4 172.3 167.8 15.7 436.4 709.5 52.7 6.9 11.8 297.9 106.5 72.0 421.9 18.9 15.9 430.9 25.8 383.4 39.1 170.3 324.4 254.4 17.9 212.1 52.0 13.5 166.4 104.7 291.5 0.7 150.1 206.1 13.9 663.1 392.1 4.4 197.4 260.8 49.9 1.4 23.5 164.0 21.5 197.7 139.2 14.0 120.5 9.8 13.1 115.7 110.3 39.7 13.0 96.3 131.2 4.4 6.0 6.9 8.5 8.7 2.0 1.4 3.1 4.6 10.1 3.7 1.8 3.8 2.8 6.6 7.4 13.0 2.9 4.9 140.2 126.7 128.5 135.0 131.8 164.8 175.1 186.2 155.1 152.0 222.9 134.2 3.2 9.6 18.8 69.9 2.0 1.7 1.3 26.9 0.0 9.1 4.7 3.0 4.2 1.5 15.1 3.7 4.2 1.7 5.2 0.5 0.0 6.9 2.2 4.7 57.7 12.2 5.4 26.7 7.4 17.8 22.0 21.0 5.1 9.5 5.1 28.3 2.5 55.8 20.5 5.0 7.7 0.2 22.4 7.2 3.1 5.3 25.7 7.0 8.8 15.0 20.7 32.1 8.2 38.7 11.9 5.1 0.0 23.7 1.4 16.9 0.1 0.7 5.4 13.2 0.0 23.8 29.5 1.3 0.5 1.2 0.6 3.1 2.5 28.3 2.0 0.9 FAIM "FAIM1, FLJ10582" ENSG00000158234 "Fas apoptotic inhibitory molecule" Q9NVQ4 3 138608606-138633376 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 235.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 173.3;Rod photoreceptor cells: 228.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 135.7" "Low region specificity" "Detected in all" "HPA042440, HPA052209" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA042440: AB_2677999, HPA052209: AB_2681761" "unprognostic (6.45e-2)" "unprognostic (8.21e-3)" "unprognostic (5.97e-2)" "unprognostic (1.11e-1)" "unprognostic (3.24e-1)" "unprognostic (8.31e-2)" "prognostic unfavorable (3.96e-5)" "unprognostic (4.84e-2)" "unprognostic (4.15e-2)" "unprognostic (9.23e-3)" "unprognostic (2.29e-1)" "unprognostic (2.63e-2)" "prognostic favorable (6.63e-4)" "unprognostic (4.76e-2)" "unprognostic (3.51e-1)" "unprognostic (3.43e-1)" "unprognostic (6.98e-2)" 18.3 8.6 16.8 6.9 17.9 4.1 15.6 17.5 21.3 31.7 14.9 9.3 6.4 12.6 19.5 12.2 38.2 12.1 6.4 16.2 18.6 15.3 8.2 10.5 10.8 18.9 17.7 10.8 38.1 8.5 10.4 8.4 19.4 14.9 7.9 235.0 9.6 21.7 5.4 8.5 6.1 9.7 19.2 4.9 9.8 7.3 17.1 19.8 20.3 5.5 13.7 13.5 10.4 19.9 80.8 15.5 1.7 13.9 14.7 27.2 55.4 24.4 14.7 25.2 21.5 26.8 23.2 0.2 21.0 32.0 29.0 20.9 66.8 13.9 28.2 66.2 69.8 15.1 42.9 39.1 16.3 0.0 4.8 38.4 26.5 9.4 14.4 15.4 27.5 5.7 10.0 20.0 15.8 30.7 0.4 68.3 30.1 2.5 15.3 81.4 18.0 2.1 40.4 39.5 26.0 22.1 43.2 23.8 64.6 16.4 40.1 20.0 16.9 5.1 11.9 25.9 12.0 0.0 0.4 135.7 20.8 0.2 21.0 16.8 2.9 2.2 10.5 3.3 9.6 17.0 5.8 8.4 6.3 12.0 3.8 9.8 0.4 18.8 2.2 4.3 6.9 4.3 16.8 17.9 17.5 21.3 16.2 18.6 18.9 17.7 19.4 19.2 17.1 19.9 16.4 19.2 22.9 9.1 12.7 10.8 30.3 35.2 14.2 31.9 14.3 21.5 5.3 68.6 32.4 25.8 66.7 42.0 14.7 5.9 31.3 63.1 12.0 173.3 29.8 14.5 21.1 7.2 7.7 50.0 33.3 16.8 8.2 41.3 41.2 17.2 8.9 9.4 25.2 15.2 6.1 8.8 14.2 3.2 5.7 16.5 17.4 6.5 16.0 1.9 15.6 45.3 21.6 11.1 16.5 31.3 4.4 19.9 14.2 22.1 2.2 28.1 77.5 228.3 0.0 25.0 22.6 14.1 4.2 16.6 13.1 14.6 10.8 14.6 11.7 21.6 FAM102A "bA203J24.7, C9orf132, Eeig1, SYM-3A" ENSG00000167106 "Family with sequence similarity 102 member A" Q5T9C2 9 127940582-127980989 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036030 Approved Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 3: HMC-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA036030: AB_10670675" "unprognostic (3.27e-1)" "unprognostic (1.66e-3)" "unprognostic (1.06e-3)" "unprognostic (4.69e-3)" "unprognostic (2.32e-1)" "unprognostic (1.21e-2)" "unprognostic (8.50e-2)" "unprognostic (2.97e-1)" "unprognostic (8.36e-2)" "unprognostic (1.01e-2)" "unprognostic (9.28e-2)" "unprognostic (1.76e-1)" "unprognostic (1.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.25e-1)" "unprognostic (8.28e-3)" "unprognostic (6.98e-2)" 11.4 40.6 63.9 35.4 86.8 13.9 19.7 64.4 77.2 52.5 20.3 38.9 55.6 33.5 19.4 61.1 47.5 46.7 14.1 59.0 58.0 37.4 39.0 16.1 59.3 76.5 79.4 20.6 35.1 22.4 51.2 9.0 70.7 23.7 17.5 14.5 44.0 20.1 4.0 45.2 65.7 27.2 60.4 27.3 105.5 32.6 91.2 40.1 23.3 3.9 44.7 37.1 47.0 144.1 26.5 56.7 11.9 9.6 25.1 30.0 45.1 10.1 27.4 6.6 4.1 33.1 46.0 29.8 6.6 19.4 14.2 28.4 6.3 5.1 2.5 14.4 6.3 8.9 14.5 30.1 15.6 4.4 66.3 12.2 26.0 18.9 8.0 13.3 9.2 18.0 7.4 36.7 7.7 68.6 17.8 9.5 14.8 52.0 27.4 9.2 8.8 10.7 19.1 44.3 18.7 9.2 16.7 36.9 23.9 12.8 69.3 5.7 9.8 10.3 11.1 55.1 15.5 49.1 72.7 20.7 44.7 5.9 24.9 0.7 0.1 2.5 1.9 0.0 6.1 4.8 9.7 5.7 0.1 1.1 8.9 6.3 0.1 0.4 0.1 0.0 13.4 3.9 63.9 86.8 64.4 77.2 59.0 58.0 76.5 79.4 70.7 60.4 91.2 144.1 3.3 6.4 9.0 37.5 37.2 21.9 29.4 11.5 24.5 15.6 44.9 26.9 11.4 41.5 14.9 64.4 10.4 6.3 10.7 91.2 7.9 61.5 7.0 51.0 35.8 8.6 28.1 8.0 13.8 100.5 5.9 12.4 99.4 46.0 18.4 22.3 54.7 49.1 3.3 26.9 12.2 42.1 40.7 6.9 8.8 7.4 34.2 3.8 23.2 5.6 4.4 69.0 1.0 26.2 103.5 59.3 51.9 43.2 22.6 69.9 131.9 12.9 33.2 14.3 0.0 6.0 7.4 9.8 10.2 38.6 47.9 5.3 40.3 13.1 28.7 122.4 FAM107B "C10orf45, FLJ45505, HITS, MGC11034" ENSG00000065809 "Family with sequence similarity 107 member B" Q9H098 10 14518557-14774897 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 526.5;Proximal tubular cells: 359.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 63.8;NK-cells: 53.8;T-cells: 106.2" "Cell line enhanced" "Detected in all" "Daudi: 373.0;HDLM-2: 449.6;Karpas-707: 309.6;THP-1: 294.4" "Low region specificity" "Detected in all" "HPA039661, HPA058814, HPA073195" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 15000 "Cluster 20: T-cells - T-cell receptor" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Golgi apparatus" "HPA039661: AB_10794751, HPA058814: AB_2683825, HPA073195: AB_2732221" "unprognostic (1.24e-1)" "unprognostic (1.91e-2)" "unprognostic (1.15e-1)" "unprognostic (1.80e-2)" "unprognostic (8.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.67e-1)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (6.82e-2)" "unprognostic (5.60e-2)" "unprognostic (4.63e-1)" "unprognostic (1.41e-1)" "unprognostic (1.80e-1)" "unprognostic (6.93e-2)" "unprognostic (7.01e-2)" "unprognostic (3.53e-2)" 48.4 44.7 82.3 90.2 150.8 171.5 44.3 112.4 112.5 42.2 90.8 64.2 32.7 48.2 11.4 22.8 20.6 66.1 11.1 84.2 102.1 119.6 147.3 64.8 152.3 136.8 125.9 7.3 70.6 70.0 21.3 22.2 130.7 27.6 42.5 15.2 68.6 113.7 3.5 22.2 55.9 31.4 95.5 50.6 122.8 37.3 118.7 48.0 12.6 9.3 134.0 66.7 17.1 223.6 60.8 129.1 50.3 3.4 7.6 1.7 21.3 59.7 85.8 35.9 25.6 79.9 49.9 373.0 52.8 27.5 13.4 18.6 16.1 36.4 63.5 449.6 13.9 10.3 55.6 95.0 26.7 136.6 23.3 4.2 28.0 14.9 7.2 42.4 154.6 72.5 1.1 309.6 28.2 15.6 33.6 39.5 12.5 72.7 28.2 240.8 39.1 140.2 81.9 39.0 18.7 53.5 23.6 12.4 39.0 44.7 46.0 294.4 50.8 37.0 31.2 118.3 20.3 136.2 131.7 241.3 6.5 117.5 10.1 52.3 6.0 63.8 100.2 7.1 97.7 12.4 79.4 85.0 5.2 12.6 105.7 106.2 25.2 53.8 14.9 3.5 78.0 74.8 82.3 150.8 112.4 112.5 84.2 102.1 136.8 125.9 130.7 95.5 118.7 223.6 12.8 105.8 44.4 7.2 203.6 89.7 147.1 25.4 16.5 4.8 94.6 30.4 4.1 134.4 52.5 286.9 2.1 18.1 194.7 65.9 223.0 44.3 27.0 234.9 98.7 37.8 14.3 22.7 1.6 106.8 38.2 49.7 175.3 268.2 119.2 32.7 72.8 177.4 37.1 201.9 7.3 110.5 36.7 53.9 120.9 53.2 2.5 110.7 51.6 15.0 68.8 13.6 198.8 11.1 526.5 90.3 44.3 4.9 176.6 139.6 25.9 359.9 85.3 15.0 0.0 5.4 64.6 56.2 35.7 8.3 82.3 62.5 237.7 3.8 39.9 240.2 FAM118A "bK268H5.C22.4, C22orf8, FLJ20635" ENSG00000100376 "Family with sequence similarity 118 member A" Q9NWS6 22 45308968-45341955 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 104.0;Early spermatids: 125.0;Syncytiotrophoblasts: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003902 Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 21: OE19 - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "Intermediate filaments" Cytosol "HPA003902: AB_1848368" "unprognostic (6.22e-3)" "unprognostic (1.19e-2)" "unprognostic (9.92e-2)" "unprognostic (1.56e-3)" "unprognostic (1.68e-1)" "unprognostic (2.09e-2)" "unprognostic (3.72e-2)" "unprognostic (7.61e-3)" "unprognostic (9.42e-2)" "unprognostic (6.11e-2)" "unprognostic (5.02e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.87e-6)" "unprognostic (9.76e-2)" "unprognostic (1.28e-1)" "unprognostic (4.50e-1)" "unprognostic (1.16e-3)" 14.1 11.8 14.9 23.7 16.9 21.5 23.3 22.0 17.1 21.9 25.5 23.3 19.9 17.7 66.5 18.6 12.2 24.4 24.5 17.2 15.6 22.9 17.1 19.3 49.1 14.4 15.3 21.7 14.3 38.3 37.6 18.3 14.4 41.7 12.4 9.5 18.4 9.3 30.5 39.7 24.8 10.3 11.4 25.9 21.3 22.7 17.9 13.6 23.7 6.5 27.6 29.7 22.8 15.8 10.9 7.8 11.0 11.9 9.3 8.9 24.0 8.1 13.4 11.5 11.2 25.6 10.1 48.6 6.5 7.5 6.5 40.7 14.3 10.3 11.5 10.6 31.9 26.3 13.2 18.7 12.8 24.8 7.2 9.5 12.3 17.6 10.8 8.0 7.1 14.6 39.5 52.6 5.9 26.1 14.7 51.3 8.2 49.8 10.4 19.0 7.1 17.4 6.6 28.9 21.8 25.6 8.9 19.0 23.9 18.0 8.2 14.4 9.2 8.8 28.8 10.8 10.8 29.0 5.5 24.7 11.9 17.1 16.0 7.1 7.1 2.2 5.8 6.2 4.7 4.3 7.3 7.2 8.8 6.5 11.5 8.6 5.8 5.6 5.0 13.5 10.9 4.4 14.9 16.9 22.0 17.1 17.2 15.6 14.4 15.3 14.4 11.4 17.9 15.8 12.5 9.6 17.0 23.8 21.2 22.6 36.9 18.8 10.8 18.3 10.9 6.6 11.3 8.6 16.6 7.3 18.8 104.0 83.1 21.4 0.0 7.0 125.0 6.7 15.5 20.7 32.9 14.5 23.1 6.2 8.5 19.2 10.2 7.4 1.3 8.8 23.9 14.5 12.9 6.7 18.3 20.5 12.2 13.0 29.9 75.6 35.8 19.8 1.8 62.8 69.5 16.4 39.1 22.6 21.5 4.8 17.7 23.7 25.8 22.6 13.4 3.9 14.6 22.3 0.0 33.6 14.7 72.5 38.8 8.8 9.9 120.9 55.2 7.3 17.5 35.4 FAM118B FLJ21103 ENSG00000197798 "Family with sequence similarity 118 member B" Q9BPY3 11 126211724-126262984 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041644, HPA042100" Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA041644: AB_10794303, HPA042100: AB_10795394" "unprognostic (8.11e-2)" "unprognostic (9.87e-3)" "unprognostic (4.05e-3)" "unprognostic (3.13e-2)" "unprognostic (9.55e-3)" "unprognostic (4.04e-2)" "prognostic unfavorable (6.67e-7)" "unprognostic (1.85e-2)" "unprognostic (3.03e-3)" "unprognostic (1.43e-1)" "unprognostic (7.12e-2)" "unprognostic (1.64e-1)" "unprognostic (3.76e-2)" "unprognostic (1.15e-1)" "unprognostic (9.49e-2)" "unprognostic (3.82e-1)" "unprognostic (7.44e-2)" 9.3 10.5 15.1 10.3 19.2 4.3 7.6 15.7 20.4 10.4 20.2 24.0 18.5 10.0 12.3 7.6 6.7 10.5 18.2 15.5 16.2 10.3 8.9 16.3 12.7 15.1 15.3 6.2 5.7 7.7 9.0 11.1 15.3 7.3 23.6 9.0 8.0 9.3 22.0 5.4 13.1 14.2 16.0 10.5 14.9 21.4 15.6 14.1 10.2 16.3 14.0 13.6 6.2 16.3 11.7 14.3 31.5 23.6 43.4 28.5 14.0 18.5 33.2 20.4 21.2 29.0 18.5 13.0 19.2 23.5 42.4 15.2 33.5 19.7 24.8 21.2 14.5 41.3 6.8 19.5 33.7 20.7 13.0 23.7 19.9 25.0 23.0 20.5 46.8 24.9 25.8 17.8 29.6 10.9 27.8 16.2 25.6 63.3 26.4 24.1 25.1 11.6 34.4 18.3 14.5 15.2 21.5 14.0 26.8 36.8 27.3 12.4 29.2 20.7 15.2 17.9 16.3 9.3 11.7 22.0 8.9 31.0 26.9 33.8 43.4 21.9 14.6 58.8 18.6 15.2 14.4 18.9 48.1 15.9 12.9 16.0 9.0 18.9 59.6 21.9 18.0 25.2 15.1 19.2 15.7 20.4 15.5 16.2 15.1 15.3 15.3 16.0 15.6 16.3 8.6 3.2 16.4 14.4 5.6 4.1 4.2 21.9 1.2 3.1 3.3 3.6 10.4 4.3 9.6 12.9 4.2 9.3 5.0 21.9 5.9 16.0 7.5 5.0 6.0 12.4 3.6 8.6 19.1 17.2 12.4 8.3 21.4 4.1 10.8 9.1 9.7 5.5 24.2 1.7 17.6 11.4 12.2 16.7 9.4 9.2 7.8 11.0 3.6 12.2 16.9 13.5 13.4 16.1 12.7 14.0 12.8 21.8 9.5 4.1 11.4 12.9 6.8 5.7 6.6 3.4 10.2 46.0 20.6 3.5 3.4 13.0 5.3 11.0 16.6 5.7 FAM131A "C3orf40, MGC21688" ENSG00000175182 "Family with sequence similarity 131 member A" Q6UXB0 3 184335926-184348421 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 55.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042800 Uncertain Approved "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli rim" "Mitotic chromosome" "HPA042800: AB_10797023" "unprognostic (1.02e-2)" "unprognostic (1.44e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (2.22e-4)" "unprognostic (2.88e-1)" "unprognostic (4.84e-2)" "unprognostic (2.92e-3)" "unprognostic (1.57e-1)" "unprognostic (7.54e-2)" "unprognostic (7.02e-2)" "unprognostic (6.54e-2)" "unprognostic (1.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.41e-2)" "unprognostic (1.56e-1)" "unprognostic (2.87e-1)" "unprognostic (1.28e-2)" 15.6 22.7 42.8 5.4 51.1 3.2 13.5 25.0 57.6 17.3 20.5 26.4 7.5 19.1 5.0 13.2 20.6 10.2 29.6 68.2 39.2 13.3 5.5 16.9 4.4 29.5 27.5 24.1 13.7 14.5 54.8 5.8 29.9 17.0 3.7 4.8 10.8 12.3 17.3 30.1 13.8 10.0 22.5 10.7 16.6 16.4 38.8 3.1 12.8 18.0 2.9 17.1 15.2 40.1 14.5 6.1 9.5 16.3 12.1 10.2 8.8 6.5 13.7 9.6 7.5 4.7 5.1 2.1 25.9 6.0 20.7 13.5 0.0 11.8 5.8 15.7 16.0 0.1 9.4 10.2 12.4 0.3 10.8 7.3 1.9 8.4 19.2 9.2 19.4 9.7 3.2 2.1 3.3 11.3 5.6 0.3 16.1 8.7 11.8 10.4 4.0 14.0 9.8 0.5 28.2 29.3 4.1 10.5 14.7 5.9 31.9 3.3 20.2 12.1 9.3 9.9 20.0 22.9 15.4 1.5 38.5 2.1 8.3 1.5 3.8 4.8 1.1 4.9 1.2 1.4 0.8 1.1 4.2 1.4 0.9 1.1 8.3 1.2 2.7 1.7 1.7 2.2 42.8 51.1 25.0 57.6 68.2 39.2 29.5 27.5 29.9 22.5 38.8 40.1 15.5 6.4 5.0 13.7 5.5 11.1 20.0 6.1 5.7 24.0 8.0 11.0 7.6 14.3 4.1 14.7 14.6 9.0 4.6 11.6 1.9 6.0 4.4 6.5 10.5 11.5 9.6 6.1 30.8 3.5 3.5 9.7 5.1 11.0 7.0 55.9 13.6 1.4 7.9 23.5 16.6 7.5 6.1 5.7 14.2 2.5 18.6 7.7 1.8 11.2 9.6 13.1 6.2 6.6 11.9 10.7 9.6 20.7 2.5 15.2 15.7 3.4 15.8 15.9 6.6 13.0 14.4 12.9 7.1 3.5 14.6 33.2 5.0 20.0 8.7 15.9 FAM160B1 "bA106M7.3, KIAA1600" ENSG00000151553 "Family with sequence similarity 160 member B1" Q5W0V3 10 114821744-114899832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 53.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043624 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA043624: AB_10797145" "unprognostic (2.61e-1)" "unprognostic (2.47e-2)" "unprognostic (2.62e-1)" "unprognostic (8.45e-3)" "unprognostic (6.43e-2)" "unprognostic (9.87e-3)" "unprognostic (7.98e-2)" "unprognostic (3.01e-1)" "unprognostic (2.29e-1)" "unprognostic (2.45e-1)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.02e-6)" "unprognostic (3.41e-3)" "unprognostic (3.35e-1)" "unprognostic (2.10e-1)" "unprognostic (1.25e-2)" 15.0 11.7 8.7 10.0 8.4 53.3 11.9 6.1 8.4 12.1 6.1 10.7 12.7 16.0 10.0 7.3 12.3 10.5 14.2 7.8 6.5 7.9 19.0 11.6 12.6 5.6 6.5 14.3 9.8 11.9 7.4 14.9 6.1 10.5 8.1 11.5 8.5 11.3 20.3 8.6 13.2 16.9 5.3 11.4 10.1 18.8 6.9 11.2 11.7 12.3 9.6 11.9 10.0 5.2 16.7 8.9 9.6 14.3 22.9 26.0 11.2 29.7 28.8 16.8 13.4 3.1 6.3 9.9 9.1 27.2 4.3 11.0 4.7 11.9 19.8 36.2 10.2 3.9 16.5 7.2 16.7 10.6 12.8 20.4 11.3 12.5 20.2 36.0 22.9 20.0 5.6 24.4 31.7 7.7 19.0 10.5 6.3 4.8 6.6 16.3 16.3 6.6 11.3 9.9 2.1 8.6 13.2 13.6 15.5 11.3 5.4 6.0 23.1 10.4 6.6 30.7 10.4 10.0 3.0 11.2 13.4 26.0 10.0 19.9 3.2 4.7 5.4 2.4 4.0 3.7 7.4 9.2 3.6 3.6 4.0 5.5 15.2 4.9 2.8 3.7 10.5 2.7 8.7 8.4 6.1 8.4 7.8 6.5 5.6 6.5 6.1 5.3 6.9 5.2 25.9 16.0 8.1 20.5 10.9 7.0 7.9 8.0 14.8 13.9 9.4 6.7 19.5 4.3 8.4 3.7 12.5 12.7 14.1 9.0 1.9 10.2 26.7 12.0 26.2 19.8 7.8 9.9 26.5 9.6 10.2 19.2 23.0 16.8 2.5 29.6 23.9 31.3 6.3 10.1 27.4 9.2 4.1 15.6 6.8 36.0 28.6 11.3 3.6 25.3 11.4 8.3 25.7 28.1 13.8 15.1 3.7 22.2 20.1 19.5 20.8 6.6 8.7 16.9 6.6 13.2 14.4 14.9 6.4 8.9 4.8 12.6 17.5 15.0 5.8 14.8 FAM160B2 "FLJ21801, RAI16" ENSG00000158863 "Family with sequence similarity 160 member B2" Q86V87 8 22089150-22104911 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025040 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm Cytosol "HPA025040: AB_1856049" "unprognostic (3.45e-1)" "unprognostic (2.08e-3)" "unprognostic (1.60e-1)" "unprognostic (8.85e-3)" "unprognostic (2.28e-2)" "prognostic favorable (4.56e-4)" "unprognostic (2.35e-2)" "unprognostic (4.82e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-2)" "unprognostic (8.38e-3)" "unprognostic (7.67e-3)" "unprognostic (3.38e-2)" "unprognostic (6.30e-2)" "unprognostic (1.08e-2)" "unprognostic (1.25e-1)" "unprognostic (2.75e-3)" 13.9 11.5 4.5 3.9 4.1 3.6 15.8 3.5 5.5 12.5 3.5 16.2 5.8 12.3 4.9 13.6 12.7 5.6 21.7 3.6 3.5 14.6 10.5 10.6 6.3 4.8 4.2 10.0 22.3 8.2 13.2 5.2 4.1 14.6 2.5 3.0 16.7 10.6 17.7 14.0 13.5 6.9 3.7 11.4 17.4 6.1 4.8 4.2 15.4 7.2 2.2 16.2 12.0 4.6 4.4 8.7 4.3 6.8 9.2 8.1 7.8 8.0 13.6 8.6 5.8 3.9 4.7 4.9 7.7 19.7 7.8 6.3 3.3 9.3 1.9 4.1 4.2 7.3 2.8 2.2 12.4 1.9 5.7 13.6 6.9 6.6 4.4 8.9 9.1 8.8 4.6 3.3 8.3 8.0 5.0 2.9 2.1 8.0 3.8 5.1 3.7 2.5 7.4 8.9 1.8 5.8 4.6 6.6 5.2 4.5 4.3 3.2 10.3 8.4 7.2 8.0 4.6 3.5 0.9 0.9 9.0 3.1 9.7 0.0 0.4 0.1 0.8 0.2 0.5 0.7 0.5 0.6 0.2 0.5 0.4 0.7 0.0 0.4 0.4 0.2 0.0 0.7 4.5 4.1 3.5 5.5 3.6 3.5 4.8 4.2 4.1 3.7 4.8 4.6 16.4 12.8 17.2 17.0 11.6 5.9 10.1 9.9 12.5 22.0 16.4 13.5 26.1 12.8 8.8 12.9 27.1 8.5 10.1 15.5 0.0 9.7 3.7 8.9 14.5 16.8 13.2 1.3 12.3 15.0 15.5 12.5 23.0 11.8 7.0 19.1 16.8 13.6 7.4 23.5 12.0 10.8 0.0 9.4 4.7 2.5 10.8 8.2 1.8 8.4 4.4 8.7 9.2 12.1 11.0 17.1 17.1 5.7 6.3 15.1 14.7 5.0 10.8 23.8 0.0 11.0 14.7 1.5 7.0 16.1 7.5 14.9 11.2 9.6 9.9 12.4 FAM171A1 "APCN, C10orf38, FLJ12884" ENSG00000148468 "Family with sequence similarity 171 member A1" Q5VUB5 10 15211643-15371289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.7" "Cell type enhanced" "Detected in many" "Astrocytes: 263.8;Cholangiocytes: 98.7;Excitatory neurons: 166.9;Oligodendrocytes: 214.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 1.7;MAIT T-cell: 4.4;memory CD4 T-cell: 2.5;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.7;naive CD8 T-cell: 2.4" "Lineage enriched" "Detected in single" 19 "T-cells: 4.7" "Cell line enhanced" "Detected in many" "TIME: 105.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051345 Approved Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" Nucleoplasm "HPA051345: AB_2681449" "unprognostic (3.60e-2)" "unprognostic (7.15e-2)" "unprognostic (2.21e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (4.11e-2)" "unprognostic (9.84e-2)" "unprognostic (9.19e-2)" "unprognostic (2.28e-1)" "unprognostic (3.97e-2)" "unprognostic (3.09e-2)" "unprognostic (1.87e-1)" "prognostic favorable (2.71e-5)" "unprognostic (3.08e-1)" "unprognostic (1.86e-1)" "prognostic unfavorable (4.90e-6)" "unprognostic (3.28e-2)" 11.0 5.0 60.1 7.5 73.2 0.5 8.8 69.8 56.4 11.8 22.7 21.6 19.1 12.8 6.4 6.4 15.6 12.9 10.6 68.5 49.5 31.9 15.4 7.4 6.0 79.6 64.8 14.2 22.4 10.9 3.7 4.1 75.6 11.2 17.6 2.6 14.1 11.9 7.6 4.2 13.0 12.3 59.3 12.4 13.3 3.5 68.7 3.9 6.9 6.1 6.6 9.0 6.3 86.7 0.0 16.2 33.3 12.6 13.2 24.9 0.4 19.5 3.9 10.2 8.8 3.0 19.2 0.1 21.5 53.4 22.7 1.4 24.0 0.2 11.5 5.9 33.4 46.7 5.2 48.1 14.3 0.0 36.0 19.7 4.9 27.8 4.0 36.8 51.4 6.8 17.5 0.2 32.8 1.4 7.7 0.1 30.4 9.3 7.8 30.4 17.0 5.1 12.7 0.0 22.4 27.6 10.9 0.2 0.1 35.0 0.2 0.6 105.6 13.9 53.6 50.4 20.8 6.3 2.1 0.1 30.3 0.0 10.8 0.0 0.0 0.0 1.7 0.0 4.4 0.0 2.5 2.2 0.0 0.0 4.7 2.4 0.0 0.2 0.0 0.0 0.5 0.9 60.1 73.2 69.8 56.4 68.5 49.5 79.6 64.8 75.6 59.3 68.7 86.7 11.1 0.0 0.0 263.8 1.0 1.3 4.0 3.1 8.0 4.0 7.6 5.7 6.8 98.7 1.7 14.7 0.0 0.1 0.2 25.4 3.9 21.1 0.7 5.9 12.5 43.7 21.0 6.5 166.9 12.2 0.2 12.3 35.7 14.6 1.3 14.4 49.2 24.7 0.4 6.7 76.6 23.7 4.1 2.8 1.7 1.1 5.3 0.3 1.8 33.7 0.7 1.5 0.0 44.2 214.4 17.5 16.1 5.7 5.2 16.5 7.3 4.5 2.4 1.1 0.0 7.5 5.9 2.3 5.7 8.0 1.8 0.1 2.0 11.4 38.8 3.6 FAM171B "FLJ34104, KIAA1946" ENSG00000144369 "Family with sequence similarity 171 member B" Q6P995 2 186694060-186765959 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8" "Group enriched" "Detected in many" 5 "Astrocytes: 258.6;Bipolar cells: 141.4;Excitatory neurons: 126.5;Inhibitory neurons: 114.2;Oligodendrocyte precursor cells: 102.1;Oligodendrocytes: 78.5" "Cancer enriched" "Detected in many" 5 "glioma: 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 43.7;U-138 MG: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010639, HPA013434" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA010639: AB_1852447, HPA013434: AB_2262499" "unprognostic (2.52e-1)" "unprognostic (7.75e-3)" "unprognostic (1.27e-1)" "unprognostic (1.04e-2)" "unprognostic (4.03e-2)" "unprognostic (9.43e-2)" "unprognostic (6.78e-3)" "unprognostic (2.68e-1)" "unprognostic (1.88e-2)" "unprognostic (1.52e-1)" "unprognostic (4.24e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (9.51e-7)" "unprognostic (4.63e-3)" "unprognostic (1.52e-1)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.03e-4)" 2.9 14.4 36.1 1.5 52.2 0.5 3.4 8.3 54.8 6.6 0.0 1.8 1.0 7.5 2.1 1.9 2.7 4.9 1.4 52.8 33.0 1.2 0.3 1.4 1.2 15.0 16.9 10.2 1.0 7.6 10.7 3.3 17.6 2.7 2.0 24.1 23.0 2.3 0.7 3.7 1.4 4.4 17.2 1.5 2.0 0.9 28.3 2.8 2.2 3.6 1.1 2.2 2.2 30.1 4.2 4.9 7.2 22.6 20.9 15.7 0.1 4.5 8.0 5.5 7.8 13.6 21.9 0.0 1.6 12.9 9.3 0.5 9.9 4.3 7.8 0.0 5.7 5.1 2.1 0.0 1.6 1.5 1.7 20.2 1.8 4.2 3.4 7.1 12.1 3.9 0.0 43.7 10.5 2.9 3.0 0.0 9.6 0.0 4.9 0.0 13.9 1.0 8.5 15.8 22.4 12.2 2.3 1.4 6.1 4.2 1.7 1.0 7.1 29.7 3.9 0.5 2.9 11.5 12.0 0.0 9.2 0.0 4.2 0.2 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.4 0.2 0.2 0.0 0.0 36.1 52.2 8.3 54.8 52.8 33.0 15.0 16.9 17.6 17.2 28.3 30.1 9.1 0.0 0.0 258.6 0.1 8.9 2.8 1.2 4.0 141.4 10.7 5.7 0.8 5.7 5.7 0.0 14.6 11.4 0.5 0.0 0.0 1.0 1.3 1.5 13.0 14.4 4.8 1.3 126.5 0.4 0.8 14.1 2.6 4.7 0.0 0.8 6.8 0.1 2.0 23.5 114.2 0.0 4.1 0.3 2.8 4.0 7.8 1.0 3.6 18.7 0.7 16.2 0.0 102.1 78.5 0.7 0.0 13.9 0.2 1.4 0.0 0.2 2.6 17.0 0.0 8.6 4.5 0.4 1.5 0.6 5.3 8.2 0.9 2.6 0.0 1.1 FAM172A "C5orf21, DKFZP564D172, Toupee" ENSG00000113391 "Family with sequence similarity 172 member A" Q8WUF8 5 93617725-94111699 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 174.3;Excitatory neurons: 259.9;Inhibitory neurons: 297.7;Microglial cells: 227.7;Oligodendrocyte precursor cells: 264.9;Oligodendrocytes: 343.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012299, HPA045505" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA012299: AB_1845724, HPA045505: AB_2679354" "unprognostic (1.12e-2)" "unprognostic (2.17e-1)" "unprognostic (3.10e-2)" "unprognostic (7.78e-2)" "unprognostic (2.03e-2)" "unprognostic (1.23e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-2)" "unprognostic (1.51e-1)" "unprognostic (1.57e-2)" "unprognostic (2.52e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.38e-1)" "unprognostic (6.56e-2)" "unprognostic (1.72e-2)" "unprognostic (1.03e-2)" 13.6 9.7 10.2 8.1 10.7 7.6 12.9 12.8 11.1 12.7 7.3 8.4 7.5 12.7 10.0 11.6 12.2 9.4 9.3 10.2 11.0 12.3 5.3 9.1 9.2 10.4 9.7 15.0 9.6 12.4 7.1 8.3 10.2 12.4 8.1 14.8 10.9 14.3 3.0 7.7 8.9 11.5 10.6 9.8 8.8 5.6 10.4 9.8 15.5 6.7 9.0 9.4 7.4 11.4 7.5 8.8 20.4 23.1 24.0 29.3 10.7 16.4 12.1 6.7 6.5 6.0 10.1 10.7 11.6 18.7 11.8 6.3 6.3 22.2 15.4 7.4 7.7 14.2 17.0 3.6 10.0 11.5 15.8 25.3 12.2 6.2 11.8 23.7 15.0 10.1 3.0 3.3 27.3 8.3 9.3 8.1 3.1 13.8 7.0 10.3 21.7 10.3 10.1 14.5 17.5 32.1 12.4 5.0 11.6 12.8 12.8 12.9 14.8 15.6 14.1 10.3 18.7 13.4 20.8 11.9 24.0 11.9 29.1 12.4 4.0 5.4 8.2 5.4 8.4 6.7 6.1 6.2 5.3 6.3 6.8 6.9 9.3 9.7 4.1 5.0 6.9 4.8 10.2 10.7 12.8 11.1 10.2 11.0 10.4 9.7 10.2 10.6 10.4 11.4 27.8 54.5 26.4 174.3 40.0 12.2 25.0 26.4 23.3 49.5 31.4 28.2 21.5 22.8 23.4 11.0 31.3 13.0 47.4 14.3 60.7 19.9 47.7 29.2 34.9 25.4 16.9 10.3 259.9 21.2 13.7 32.6 21.9 21.9 25.3 22.7 21.8 14.9 11.3 42.1 297.7 13.9 22.4 21.3 12.1 34.2 38.5 18.0 21.4 227.7 27.9 37.4 58.7 264.9 343.8 20.1 14.7 36.5 17.3 19.7 27.7 35.2 47.5 54.5 13.1 39.5 30.7 22.4 26.1 25.8 10.1 10.9 37.4 30.7 16.4 24.4 FAM177A1 C14orf24 ENSG00000151327 "Family with sequence similarity 177 member A1" Q8N128 14 35044907-35113130 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 637.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053222, HPA055440" Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 170000 "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" Vesicles Nucleoplasm "HPA053222: AB_2682083, HPA055440: AB_2682817" "unprognostic (6.86e-2)" "unprognostic (2.03e-1)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (1.91e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (4.64e-3)" "unprognostic (6.28e-2)" "unprognostic (7.79e-2)" "prognostic favorable (8.51e-5)" "unprognostic (1.12e-2)" "unprognostic (7.22e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (1.69e-1)" "unprognostic (8.28e-2)" "unprognostic (1.91e-1)" 45.3 43.2 36.8 30.0 50.1 49.6 38.2 45.3 46.5 44.2 36.9 81.5 57.2 29.4 29.6 49.7 26.8 37.7 78.1 39.0 51.3 61.3 77.0 68.6 20.2 52.4 50.6 28.2 49.4 30.6 47.4 27.3 49.1 63.1 71.5 31.3 43.4 36.1 48.3 41.3 54.6 42.3 45.0 23.6 42.5 86.2 47.0 21.6 48.0 32.8 23.2 46.7 37.7 57.0 63.4 51.2 38.0 31.3 64.6 64.6 46.7 101.3 55.8 52.4 57.1 52.2 82.6 25.1 68.1 98.9 71.1 65.8 47.1 58.5 66.7 73.5 28.8 19.5 63.8 179.5 79.4 30.7 44.9 58.5 75.3 63.5 49.5 76.7 60.6 46.7 47.7 79.8 102.5 91.5 38.0 28.1 30.9 100.9 65.2 21.9 52.7 35.9 95.2 68.7 52.1 45.9 119.3 94.2 81.3 75.2 87.2 23.9 71.3 67.5 59.2 76.6 53.2 59.3 79.8 31.2 42.3 20.5 68.0 79.9 43.9 79.2 31.0 36.7 36.5 45.0 40.3 35.7 34.8 35.8 31.7 31.4 167.5 32.6 31.9 50.8 60.0 30.4 36.8 50.1 45.3 46.5 39.0 51.3 52.4 50.6 49.1 45.0 47.0 57.0 126.7 240.4 176.3 6.5 87.4 160.7 199.4 200.4 83.6 35.8 119.0 118.4 147.8 67.2 168.1 104.8 27.1 71.0 322.2 329.3 119.3 121.9 637.1 235.5 86.6 116.4 133.8 36.0 10.7 249.6 118.0 80.5 107.0 426.4 82.3 43.1 82.5 235.6 75.5 23.5 13.4 189.5 144.5 61.1 130.9 505.9 54.0 85.4 149.4 8.4 125.1 45.3 48.4 9.0 28.4 364.6 220.1 53.0 133.3 211.4 273.7 347.2 177.8 45.5 46.0 65.2 106.2 189.3 106.8 93.1 171.5 123.3 215.7 30.4 224.2 229.5 FAM180A "HWKM1940, UNQ1940" ENSG00000189320 "Family with sequence similarity 180 member A" Q6UWF9 7 135728348-135748813 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.1;heart muscle: 15.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Cardiomyocytes: 6.6;Fibroblasts: 19.7;Hepatic stellate cells: 4.6;Langerhans cells: 9.5;Melanocytes: 7.2;Suprabasal keratinocytes: 4.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-2197: 259.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA021224 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA021224: AB_1851352" "unprognostic (3.85e-2)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.27e-1)" "unprognostic (5.05e-2)" "unprognostic (1.97e-3)" "unprognostic (5.62e-2)" "unprognostic (7.55e-2)" "unprognostic (8.88e-4)" "unprognostic (3.14e-3)" "unprognostic (1.82e-1)" "unprognostic (4.35e-4)" "unprognostic (6.62e-4)" 3.1 2.7 0.0 0.5 0.1 0.1 3.4 0.1 0.3 2.6 4.2 1.8 0.8 4.7 0.4 4.0 2.0 16.1 15.9 0.3 0.0 4.1 10.2 2.5 0.1 0.0 0.0 7.9 1.3 0.2 0.1 0.2 0.0 0.6 2.0 0.0 1.2 0.2 0.3 3.4 1.3 4.7 0.0 0.6 1.0 0.4 0.0 0.2 2.7 1.3 0.5 4.4 1.3 0.1 0.0 0.1 0.0 0.0 27.8 28.4 0.0 14.9 56.2 0.3 0.2 0.0 0.0 0.0 0.0 57.8 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 2.6 0.0 35.6 4.6 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.6 57.1 0.0 259.7 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.8 6.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.8 0.0 0.0 0.3 0.0 0.0 19.7 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.5 0.0 2.8 0.1 7.2 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 1.8 0.0 0.0 0.1 4.8 0.7 0.2 0.0 0.0 0.0 FAM180B LOC399888 ENSG00000196666 "Family with sequence similarity 180 member B" Q6P0A1 11 47586678-47589194 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 6.5;brain: 5.9;breast: 5.2;choroid plexus: 5.1;skin 1: 6.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.4;Fibroblasts: 20.4;Langerhans cells: 11.9;Melanocytes: 5.4;Peritubular cells: 4.1;Suprabasal keratinocytes: 6.3" "Cancer enhanced" "Detected in some" "melanoma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA029408 Uncertain "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA029408: AB_10601319" "unprognostic (1.28e-2)" "unprognostic (4.99e-3)" "unprognostic (7.48e-2)" "unprognostic (7.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.64e-2)" "unprognostic (1.21e-3)" "unprognostic (1.04e-1)" "unprognostic (2.69e-1)" "unprognostic (3.87e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-5)" "unprognostic (5.65e-2)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" 6.5 0.1 0.8 0.0 2.0 0.1 5.2 5.9 1.7 0.4 5.1 0.6 0.0 0.2 0.0 0.1 0.4 0.4 0.7 0.6 0.8 0.0 0.0 0.2 0.0 1.9 1.3 0.1 0.1 0.0 0.2 0.0 1.5 0.0 0.0 0.1 1.1 0.0 1.0 6.3 0.2 0.1 1.3 0.1 0.5 0.5 1.6 0.7 4.3 2.9 0.1 0.4 0.2 2.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.0 5.9 1.7 0.6 0.8 1.9 1.3 1.5 1.3 1.6 2.6 0.8 0.0 0.0 1.0 0.0 7.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.0 20.4 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.6 11.9 0.3 2.5 0.3 5.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.0 6.3 0.1 0.3 0.0 0.0 0.0 FAM189A1 "KIAA0574, TMEM228" ENSG00000104059 "Family with sequence similarity 189 member A1" O60320 15 29120254-29570723 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 5.3;thyroid gland: 3.2" "Group enriched" "Detected in some" 5 "Excitatory neurons: 202.9;Inhibitory neurons: 198.0;Oligodendrocyte precursor cells: 59.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 4.6;HDLM-2: 12.0;REH: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009410, HPA010637" Uncertain Approved Nucleoplasm NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA009410: AB_1852332, HPA010637: AB_1852333" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (5.81e-2)" "unprognostic (6.52e-2)" "unprognostic (7.05e-2)" "unprognostic (4.71e-2)" "unprognostic (4.85e-3)" "unprognostic (2.21e-1)" "unprognostic (1.27e-1)" "unprognostic (3.39e-1)" "unprognostic (7.97e-2)" "unprognostic (5.00e-1)" "unprognostic (6.70e-3)" "unprognostic (2.39e-2)" "unprognostic (9.03e-2)" "unprognostic (2.50e-2)" "unprognostic (3.12e-1)" 0.6 0.4 2.2 0.0 1.8 0.0 0.1 0.0 2.4 0.3 0.3 2.6 0.1 0.2 0.0 0.0 1.0 0.0 0.8 2.5 0.4 2.1 0.1 1.1 0.0 0.2 0.3 0.2 5.3 0.4 0.4 0.0 0.2 0.4 0.5 0.1 0.6 0.0 0.0 0.1 0.9 0.0 0.0 0.2 0.4 2.0 1.2 0.0 3.2 0.0 0.1 0.9 0.2 0.8 0.0 0.0 1.2 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.2 0.0 0.0 0.0 0.1 12.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 1.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.8 0.0 2.4 2.5 0.4 0.2 0.3 0.2 0.0 1.2 0.8 0.5 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 4.3 0.8 0.0 0.0 0.4 3.0 0.0 202.9 0.2 0.0 0.7 0.0 0.1 0.0 0.3 0.7 0.0 0.1 0.0 198.0 2.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 29.0 0.0 0.2 0.0 59.8 8.1 0.2 2.6 1.5 0.0 1.0 2.2 0.8 0.0 0.4 0.0 0.0 0.2 0.6 1.7 0.0 0.0 0.0 0.0 1.0 3.2 0.4 FAM20A DKFZp434F2322 ENSG00000108950 "FAM20A golgi associated secretory pathway pseudokinase" Q96MK3 17 68535113-68601367 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 50.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 82.4;Early spermatids: 69.0;Hepatocytes: 66.8;Hofbauer cells: 94.0;Late spermatids: 189.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 10.1;BJ hTERT+: 27.3;HSkMC: 21.8;U-2197: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048964 Approved "Secreted in other tissues" NA NA 13000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "HPA048964: AB_2680575" "unprognostic (3.68e-2)" "unprognostic (3.14e-2)" "unprognostic (3.35e-2)" "unprognostic (4.49e-3)" "unprognostic (6.56e-2)" "unprognostic (5.29e-2)" "unprognostic (3.90e-3)" "unprognostic (2.39e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (9.16e-10)" "unprognostic (1.25e-3)" "unprognostic (1.06e-1)" "unprognostic (4.55e-2)" "unprognostic (2.39e-2)" 7.5 1.6 0.4 2.7 0.3 0.6 5.4 0.3 0.6 17.5 2.6 1.6 0.6 12.5 0.1 3.1 6.0 1.3 3.1 0.1 1.1 12.9 50.2 12.6 1.6 0.8 1.7 8.1 1.0 0.3 6.3 2.2 0.7 2.5 0.4 0.1 11.6 0.6 1.6 2.5 2.0 2.3 0.1 4.5 7.8 6.5 3.6 0.4 6.8 0.1 0.5 2.2 5.7 0.7 0.0 0.2 0.0 0.2 1.1 10.1 0.0 0.5 27.3 0.0 0.0 0.0 0.1 0.0 2.0 2.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.1 0.0 21.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.1 0.0 0.0 0.1 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.4 0.3 0.3 0.6 0.1 1.1 0.8 1.7 0.7 0.1 3.6 0.7 1.4 16.0 82.4 0.7 1.1 2.3 0.1 5.2 0.0 3.2 5.3 0.9 5.2 7.2 21.3 44.1 0.0 0.6 0.4 0.0 0.0 1.2 69.0 6.1 44.4 3.6 0.0 2.7 3.8 0.5 2.2 18.1 42.3 9.7 1.3 2.9 7.5 66.8 94.0 42.1 8.2 0.0 2.0 27.4 3.5 189.3 11.1 26.8 1.8 16.9 1.3 0.2 0.0 4.0 2.1 0.8 0.0 14.7 0.2 0.0 0.0 15.3 0.8 2.8 6.6 3.4 3.0 1.2 0.6 1.2 1.8 2.7 1.0 13.6 0.0 0.1 FAM20C "DKFZp547D065, DMP4, G-CK, IMAGE:4942737" ENSG00000177706 "FAM20C golgi associated secretory pathway kinase" Q8IXL6 7 192571-260772 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Biomineralization "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 55.2;Hepatocytes: 94.0;Hofbauer cells: 54.9;Peritubular cells: 56.4;Proximal tubular cells: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 55.3;hTERT-RPE1: 39.9;U-87 MG: 36.0;WM-115: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019823 Approved "Nucleoplasm,Golgi apparatus" "Secreted in other tissues" NA NA 240000000 "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Nucleoplasm "HPA019823: AB_1848389" "unprognostic (1.94e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (3.15e-2)" "unprognostic (1.03e-2)" "unprognostic (3.33e-3)" "unprognostic (2.47e-2)" "unprognostic (7.86e-2)" "unprognostic (2.45e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (9.40e-6)" "unprognostic (1.97e-3)" "unprognostic (2.49e-1)" "unprognostic (3.08e-3)" "unprognostic (1.94e-2)" "unprognostic (3.92e-2)" "unprognostic (2.16e-2)" "unprognostic (3.83e-3)" 32.5 14.8 7.0 7.3 5.7 1.5 32.8 5.0 7.0 19.4 0.8 44.3 4.5 19.4 2.1 14.3 20.2 5.9 30.2 4.3 5.0 34.9 56.5 27.9 1.1 12.5 9.7 20.3 13.4 1.6 18.3 2.6 6.7 29.9 1.4 1.1 20.3 3.6 30.7 14.7 23.3 6.8 6.4 8.9 38.9 7.8 12.6 0.6 19.6 6.3 0.6 36.8 15.1 6.2 19.6 6.4 0.3 10.3 11.8 20.3 0.0 17.4 23.2 7.9 5.9 0.9 10.1 0.0 9.3 21.8 10.4 14.9 1.1 0.6 1.6 4.5 0.6 0.0 3.1 3.4 8.8 0.0 1.0 55.3 1.6 0.3 0.7 39.9 5.0 0.0 0.0 0.0 1.8 1.9 0.0 0.7 8.9 0.1 0.3 2.3 0.5 0.0 4.9 0.0 4.4 0.2 17.2 0.0 2.3 1.1 9.7 6.5 14.6 10.3 5.3 7.7 5.3 0.0 0.0 0.0 36.0 1.0 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 5.7 5.0 7.0 4.3 5.0 12.5 9.7 6.7 6.4 12.6 6.2 5.0 6.4 5.1 11.8 1.2 10.1 2.3 4.5 1.8 26.9 27.6 18.7 9.9 21.5 1.0 55.2 0.0 0.5 4.6 3.4 5.9 1.8 0.0 4.1 19.0 4.5 11.9 0.4 7.4 4.8 0.5 22.6 13.7 9.5 3.8 3.1 9.3 94.0 54.9 1.7 17.0 5.3 2.0 24.4 9.8 2.6 16.1 34.5 1.8 5.6 10.8 17.1 0.0 8.5 15.3 6.3 3.7 56.4 0.1 6.6 33.7 48.7 3.4 9.0 13.1 8.7 17.3 0.3 1.0 3.5 8.1 0.5 0.9 0.6 9.0 1.9 FAM237A ENSG00000235118 "Family with sequence similarity 237 member A" A0A1B0GTK4 2 206642487-206649365 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Low region specificity" "Detected in single" NA NA "unprognostic (3.02e-1)" 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.2 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.7 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.8 0.6 0.7 0.3 0.3 0.3 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 FAM24A AC073585.4 ENSG00000203795 "Family with sequence similarity 24 member A" A6NFZ4 10 122910610-122913111 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 118 "testis: 17.6" "Cell type enriched" "Detected in some" 10 "Early spermatids: 303.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052490 Supported "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA052490: AB_2681851" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 303.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FAM24B "AC073585.2, MGC45962" ENSG00000213185 "Family with sequence similarity 24 member B" Q8N5W8 10 122849078-122879641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 50.9;Early spermatids: 28.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "hTERT-HME1: 135.5;LHCN-M2: 181.8;TIME: 58.3" HPA052490 Supported "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" "HPA052490: AB_2681851" "unprognostic (4.03e-2)" "unprognostic (4.27e-2)" "unprognostic (3.13e-3)" "unprognostic (8.40e-5)" "unprognostic (2.55e-2)" "unprognostic (3.31e-2)" "unprognostic (6.42e-7)" "unprognostic (2.99e-1)" "unprognostic (7.06e-3)" "unprognostic (3.00e-1)" "unprognostic (5.89e-2)" "unprognostic (3.59e-2)" "unprognostic (1.78e-1)" "unprognostic (2.58e-1)" "unprognostic (9.23e-2)" "unprognostic (1.25e-1)" "unprognostic (8.81e-3)" 2.1 1.3 4.9 2.6 5.0 2.6 3.0 4.9 6.4 2.8 3.7 2.8 2.3 2.3 2.9 2.4 2.2 2.1 1.5 5.2 6.3 15.0 0.9 2.4 5.9 5.3 5.0 2.9 7.8 1.0 10.9 0.4 5.2 3.0 4.0 5.9 1.9 1.4 0.9 4.2 3.6 1.6 4.9 3.8 3.1 9.2 5.2 4.9 2.4 0.2 4.7 2.6 2.3 5.8 8.1 12.8 3.1 0.1 1.9 3.7 4.0 11.8 11.1 4.8 4.4 14.2 16.6 3.0 3.6 6.5 1.4 5.2 0.0 7.1 13.1 14.0 5.3 23.8 18.4 7.6 10.4 0.0 13.8 4.3 0.9 10.4 135.5 0.9 12.6 15.5 9.5 6.0 181.8 7.3 13.9 13.9 5.0 8.1 13.3 0.0 18.5 2.8 8.6 7.2 8.6 3.7 5.5 2.9 15.0 7.7 4.7 14.1 58.3 1.4 6.7 5.0 1.2 6.5 7.1 18.0 9.7 23.3 0.0 2.2 1.5 1.0 1.7 1.5 0.6 4.2 3.4 2.4 2.1 2.3 3.5 2.1 1.0 2.1 1.5 8.1 3.6 1.2 4.9 5.0 4.9 6.4 5.2 6.3 5.3 5.0 5.2 4.9 5.2 5.8 2.5 0.0 0.5 0.0 7.1 6.6 1.6 4.2 14.2 3.6 3.7 5.8 0.2 2.8 1.2 9.2 0.0 0.1 7.7 1.6 50.9 4.3 28.2 0.5 0.7 1.9 4.8 6.5 0.0 7.3 0.2 3.8 2.0 0.6 8.9 0.5 1.8 0.8 1.2 1.7 0.0 3.5 12.2 4.1 2.9 4.1 3.7 3.3 1.8 0.0 3.5 2.9 8.2 0.0 0.0 8.7 2.7 4.1 2.7 2.0 2.3 1.8 1.2 4.3 0.0 1.7 2.3 12.9 4.6 5.5 5.4 0.0 6.7 0.2 3.5 1.2 FAM72B RP11-439A17.6 ENSG00000188610 "Family with sequence similarity 72 member B" Q86X60 1 121167646-121185539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.2;lymphoid tissue: 10.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7.3;Early spermatids: 11.3;Erythroid cells: 5.9;Hepatic stellate cells: 6.4;Spermatocytes: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (8.53e-2)" "unprognostic (1.97e-2)" "unprognostic (1.63e-3)" "unprognostic (1.25e-3)" "unprognostic (4.36e-1)" "unprognostic (1.05e-1)" "unprognostic (1.26e-4)" "unprognostic (8.22e-5)" "unprognostic (1.30e-2)" "unprognostic (1.79e-2)" "unprognostic (1.36e-4)" "unprognostic (2.46e-2)" "unprognostic (0.00e+0)" "unprognostic (2.39e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-2)" "unprognostic (5.30e-2)" 0.8 0.6 1.2 3.7 1.0 6.2 0.8 2.0 1.1 0.5 1.3 1.1 1.3 0.5 0.4 1.6 0.4 1.0 0.3 1.2 1.2 0.4 0.4 0.6 8.1 1.6 1.4 0.4 0.2 0.7 0.2 1.4 1.6 0.2 1.2 0.1 0.4 0.2 0.1 1.9 1.1 0.7 1.3 2.0 1.0 2.3 1.3 10.3 0.3 0.2 6.6 0.8 0.7 1.4 28.6 10.3 16.5 8.2 1.6 2.4 13.3 14.7 6.2 16.8 14.1 0.1 14.5 62.9 19.9 2.7 16.4 17.1 23.1 8.3 25.9 41.1 17.3 27.2 12.0 12.5 1.0 47.7 23.2 1.3 0.9 13.0 26.5 4.2 10.3 51.0 36.1 37.3 12.4 12.1 24.1 39.1 31.6 14.9 20.6 35.8 35.8 28.7 6.7 3.2 18.0 10.4 11.1 8.6 8.6 16.9 11.4 36.5 3.6 13.8 23.5 27.3 26.6 32.6 44.1 61.3 12.4 50.8 32.6 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.4 0.3 1.2 1.0 2.0 1.1 1.2 1.2 1.6 1.4 1.6 1.3 1.3 1.4 1.3 0.0 0.0 0.0 1.6 1.0 0.1 0.2 0.0 0.0 0.3 0.6 0.4 0.0 0.1 0.0 0.0 0.8 0.1 7.3 0.0 0.2 11.3 0.2 0.4 2.5 0.0 5.9 0.1 0.2 2.3 0.6 1.1 0.2 0.0 0.5 6.4 0.0 1.1 0.0 0.3 4.9 0.0 1.9 2.8 3.0 0.6 1.6 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.1 2.3 0.0 2.5 0.0 2.1 0.0 0.7 0.0 0.0 0.3 0.9 17.0 3.1 3.5 1.0 0.1 1.2 0.2 3.6 0.0 FAM78A "C9orf59, FLJ00024" ENSG00000126882 "Family with sequence similarity 78 member A" Q5JUQ0 9 131258076-131276510 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 53.7;testis: 31.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.7;Early spermatids: 90.6;Granulosa cells: 167.2;Late spermatids: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 39.3;HEL: 38.6;HL-60: 38.7;NB-4: 60.7;THP-1: 53.5;U-937: 35.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021472, HPA023914" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "HPA021472: AB_1848411, HPA023914: AB_1848412" "unprognostic (5.16e-2)" "prognostic favorable (3.67e-4)" "unprognostic (3.65e-2)" "unprognostic (2.07e-2)" "unprognostic (2.71e-1)" "prognostic favorable (2.00e-4)" "unprognostic (3.24e-1)" "unprognostic (5.49e-2)" "unprognostic (1.46e-2)" "unprognostic (5.83e-1)" "unprognostic (5.84e-2)" "unprognostic (6.79e-2)" "unprognostic (1.59e-3)" "unprognostic (2.61e-3)" "unprognostic (7.42e-2)" "unprognostic (2.61e-2)" "unprognostic (2.39e-1)" 2.9 2.0 3.8 13.8 5.6 21.7 1.7 3.6 6.3 1.4 1.8 2.4 2.7 1.5 0.3 1.7 1.3 3.1 26.5 5.1 3.7 1.6 1.5 6.1 24.5 5.6 4.1 1.4 1.1 1.1 1.2 5.3 4.9 1.4 1.6 4.6 2.7 0.9 53.7 1.2 8.9 1.8 4.6 21.6 3.8 31.9 5.8 21.1 1.6 20.2 14.9 3.5 1.1 5.7 0.7 0.3 2.5 5.6 1.7 0.5 39.3 0.3 0.3 0.5 0.2 0.3 0.2 17.1 0.2 0.3 0.8 0.1 16.0 0.2 0.1 4.4 1.4 38.6 0.6 0.3 0.6 38.7 1.5 0.4 0.8 0.0 0.1 0.5 22.2 10.8 13.8 4.7 0.5 6.0 1.7 60.7 2.6 0.3 0.6 4.0 2.3 23.7 0.2 0.1 1.5 2.1 2.3 0.8 2.4 0.9 1.4 53.5 0.6 2.3 2.4 1.3 0.1 3.4 1.9 9.7 0.3 35.9 0.6 0.5 9.7 17.6 9.2 12.6 7.4 14.2 8.9 10.1 6.0 15.9 11.0 9.3 9.8 3.1 9.9 2.7 9.5 8.7 3.8 5.6 3.6 6.3 5.1 3.7 5.6 4.1 4.9 4.6 5.8 5.7 3.2 0.0 1.5 0.0 15.5 0.9 0.0 0.0 0.0 55.7 0.4 0.5 17.6 0.0 0.0 1.8 0.0 1.1 19.0 0.0 0.0 0.1 90.6 0.1 0.2 6.8 0.0 3.4 5.0 0.0 37.6 3.1 0.5 0.1 1.3 167.2 6.4 0.5 25.7 0.0 1.7 0.0 0.0 21.7 10.6 120.3 5.0 14.8 1.8 15.9 15.6 0.8 30.9 1.0 0.1 0.1 0.0 3.4 12.0 0.0 0.0 0.2 0.0 1.8 0.0 0.6 6.3 2.2 1.2 0.0 0.9 1.4 17.4 1.0 0.0 0.1 FAM98B FLJ38426 ENSG00000171262 "Family with sequence similarity 98 member B" Q52LJ0 15 38454127-38487710 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008320, HPA008502" Enhanced Supported Nucleoplasm,Vesicles NA NA 20000 "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "HPA008320: AB_1848419, HPA008502: AB_1848420" "unprognostic (1.05e-2)" "unprognostic (3.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.00e-2)" "unprognostic (1.54e-2)" "unprognostic (3.09e-2)" "unprognostic (9.25e-3)" "unprognostic (1.74e-1)" "unprognostic (4.69e-2)" "unprognostic (2.18e-1)" "unprognostic (3.15e-1)" "unprognostic (3.15e-2)" "unprognostic (1.51e-2)" "unprognostic (2.26e-1)" "unprognostic (4.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" 12.7 11.4 9.5 12.8 10.2 9.8 12.9 16.4 12.6 9.7 7.2 15.4 9.6 13.3 9.0 9.0 8.1 7.0 12.4 10.8 10.9 13.1 7.8 8.1 13.8 9.4 9.7 11.2 6.1 19.3 6.4 12.0 10.0 12.1 11.6 19.8 6.3 10.0 13.8 8.8 10.0 9.5 10.1 11.2 9.5 8.5 9.6 28.6 11.7 16.3 13.3 11.9 7.0 12.6 30.7 16.2 77.7 40.0 14.1 25.7 37.9 38.6 28.2 37.4 37.5 35.8 14.4 21.1 41.4 32.2 37.9 31.8 47.4 39.5 52.2 21.8 25.7 62.6 33.9 27.8 20.4 59.8 34.6 23.9 24.1 33.3 38.5 27.4 38.9 45.7 45.6 25.7 36.0 13.8 50.7 31.8 42.0 34.8 22.3 53.3 42.0 17.7 32.8 39.9 47.8 48.9 42.5 27.0 19.8 34.6 33.0 36.6 32.7 42.1 51.5 28.2 44.0 47.6 46.1 78.3 23.1 38.9 44.8 2.3 0.5 1.4 2.8 0.4 2.4 1.6 2.8 2.3 0.6 1.9 3.4 2.6 0.4 2.2 0.6 1.4 1.9 0.4 9.5 10.2 16.4 12.6 10.8 10.9 9.4 9.7 10.0 10.1 9.6 12.6 17.9 16.0 21.4 16.3 16.8 14.7 12.7 14.1 14.2 36.8 15.2 11.6 48.9 12.8 18.1 16.5 16.7 30.6 16.4 11.0 7.9 16.4 3.4 19.1 21.5 16.9 12.6 16.6 22.5 19.8 22.4 16.6 16.8 17.0 13.3 18.4 16.8 13.1 12.6 20.2 20.5 22.6 12.2 15.8 12.2 2.5 12.5 10.9 5.4 18.7 21.4 18.5 21.6 12.1 23.8 14.3 9.8 17.0 18.2 12.4 11.1 12.7 18.8 27.9 6.6 21.5 16.2 27.2 17.1 19.7 14.8 21.5 15.3 14.7 19.3 14.1 FAM9B TEX39B ENSG00000177138 "Family with sequence similarity 9 member B" Q8IZU0 X 9024232-9295682 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 3.1;testis: 5.9" "Group enriched" "Detected in some" 16 "Spermatocytes: 114.8;Spermatogonia: 96.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 65 "U-266/70: 27.8;U-266/84: 32.1" HPA035135 Uncertain Uncertain Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "HPA035135: AB_10669999" "unprognostic (3.95e-1)" "unprognostic (4.49e-1)" "unprognostic (3.76e-2)" "unprognostic (1.28e-1)" "unprognostic (1.48e-1)" "unprognostic (1.40e-2)" "unprognostic (2.62e-1)" "unprognostic (6.08e-10)" "unprognostic (4.08e-1)" "unprognostic (1.21e-1)" "unprognostic (1.54e-2)" 0.0 0.1 0.3 0.0 0.2 0.3 0.0 0.3 0.3 0.1 0.2 0.2 0.0 1.5 1.4 0.0 0.0 0.0 0.0 0.2 0.3 0.0 3.1 0.1 0.0 0.2 0.2 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.7 0.0 0.1 0.3 0.8 0.0 0.4 0.2 5.9 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.5 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 27.8 32.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.3 0.2 0.3 0.2 0.2 0.2 0.0 0.4 0.5 0.1 0.0 1.1 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.4 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.1 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 4.9 0.2 1.7 0.4 0.0 0.0 0.3 0.0 2.8 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.5 6.6 0.6 0.2 114.8 96.5 0.0 0.3 0.0 0.2 0.0 0.0 0.2 FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "FA complementation group A" O15360 16 89737549-89816657 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.2;testis: 21.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 44.1;Spermatogonia: 38.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA063236: AB_2684966" "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" 1.4 1.9 1.7 6.7 1.9 20.2 1.9 2.4 3.3 2.1 1.5 5.5 5.2 1.2 0.8 6.6 2.0 1.2 1.6 1.8 1.2 2.9 6.1 3.4 12.5 1.4 1.1 1.4 1.9 1.4 1.9 4.1 1.5 1.7 6.2 1.0 2.1 0.6 0.7 5.2 5.6 2.1 1.1 6.7 3.6 21.6 1.5 8.1 1.7 0.6 13.5 2.2 2.7 1.9 23.2 34.8 40.8 35.7 2.6 5.2 31.2 28.2 15.3 46.5 19.5 30.6 37.3 56.2 12.9 9.8 15.5 34.7 27.7 21.1 48.8 13.4 46.5 16.6 49.1 63.4 1.7 17.1 17.5 1.7 2.2 37.8 12.0 6.6 14.9 28.0 40.9 16.9 24.6 53.6 34.6 73.7 26.5 31.5 21.3 61.4 32.8 10.3 11.8 21.5 36.3 19.7 41.9 12.3 5.4 23.3 22.4 30.4 11.1 37.0 38.9 20.9 30.0 15.1 19.0 56.3 17.5 37.8 36.1 2.5 7.4 9.9 4.2 8.5 3.0 7.0 2.4 3.7 6.2 4.6 0.6 2.6 9.4 8.2 9.2 0.4 9.2 4.2 1.7 1.9 2.4 3.3 1.8 1.2 1.4 1.1 1.5 1.1 1.5 1.9 1.5 0.0 1.1 0.7 9.6 3.4 1.6 2.6 0.0 8.1 3.0 2.0 2.9 0.0 3.5 16.5 10.4 16.0 12.3 5.1 1.9 2.0 5.9 2.8 3.5 2.1 1.8 20.8 10.0 1.6 9.9 3.3 9.2 3.4 2.5 19.0 5.3 4.7 8.8 3.3 5.7 8.1 2.0 4.1 3.1 4.1 1.5 6.8 0.0 1.0 3.0 1.1 21.6 3.0 1.7 1.9 1.7 0.0 21.1 1.3 6.6 10.4 6.4 7.7 0.0 2.7 3.5 44.1 38.5 3.8 1.8 25.3 9.3 6.8 11.4 2.6 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4;smooth muscle: 26.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 67.6;Fibroblasts: 43.4;Microglial cells: 17.8;Muller glia cells: 57.5;Smooth muscle cells: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 192.2;ASC TERT1: 202.3;BJ hTERT+: 167.8;hTERT-RPE1: 209.1;U-138 MG: 167.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 3.1;hippocampal formation: 2.4" HPA059739 Uncertain "Secreted to blood" NA NA 108000000 56000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA059739: AB_2684117" "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 5.8 0.2 0.9 5.2 0.9 0.0 10.1 0.4 0.9 15.2 0.0 3.5 0.5 31.4 8.5 3.6 4.8 22.3 4.9 0.3 1.4 0.7 0.2 4.0 1.5 0.6 0.5 3.0 2.5 0.7 0.5 23.1 0.6 1.9 2.5 6.4 4.7 5.8 4.4 2.8 0.9 26.4 0.2 0.4 1.0 1.5 1.0 0.5 2.8 7.5 1.5 15.5 3.6 0.7 0.0 0.0 0.0 0.0 192.2 202.3 0.4 82.8 167.8 16.6 25.4 0.0 0.0 0.0 0.6 31.3 0.0 0.1 0.0 5.1 8.0 0.0 0.0 0.1 1.2 0.0 19.5 0.0 0.0 66.2 1.2 28.1 5.2 209.1 0.1 0.0 0.0 0.0 53.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.5 0.0 9.0 0.2 0.1 0.0 84.3 167.3 3.1 41.4 0.4 0.0 0.1 0.0 37.5 0.1 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.4 0.9 0.3 1.4 0.6 0.5 0.6 0.2 1.0 0.7 3.9 0.0 0.0 5.5 0.2 4.5 0.1 7.0 0.0 1.8 0.3 0.5 0.4 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.2 6.7 3.4 67.6 6.4 4.9 0.0 13.3 0.2 1.9 43.4 0.0 6.2 0.0 0.0 1.4 0.0 0.9 1.7 0.3 1.4 0.0 0.0 2.6 4.1 8.4 0.8 3.6 17.8 0.0 57.5 0.0 0.5 4.2 1.0 0.0 0.0 0.3 0.0 0.0 1.2 0.2 2.0 0.0 4.7 25.2 2.3 0.4 0.4 4.3 1.8 0.8 1.3 0.2 0.0 FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88990531-89017059 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 114.7" "Group enriched" "Detected in all" 5 "granulocytes: 114.7;T-cells: 96.2" "Cell line enhanced" "Detected in many" "HDLM-2: 83.4;Karpas-707: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11900000 420000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: AB_10601378" "unprognostic (6.84e-2)" "unprognostic (2.88e-3)" "unprognostic (8.38e-3)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (9.56e-2)" "unprognostic (7.00e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.32e-2)" "unprognostic (4.95e-3)" "unprognostic (1.65e-1)" 14.1 26.3 3.6 17.0 3.6 20.8 10.9 2.9 4.7 12.7 2.8 16.4 7.0 12.8 10.3 10.8 14.8 15.7 7.5 3.6 3.7 7.2 23.3 21.7 18.9 4.6 3.1 20.1 3.7 2.7 3.7 10.4 4.0 8.9 23.3 3.3 6.5 9.3 2.3 9.4 9.2 15.0 3.5 11.2 4.4 2.6 3.9 14.4 7.3 2.6 15.6 12.9 10.2 4.3 22.7 8.2 5.4 13.9 37.0 51.3 0.0 51.8 50.2 1.7 9.1 0.1 23.4 4.7 19.0 52.1 9.6 4.0 1.0 44.8 3.2 83.4 8.7 0.4 5.2 14.7 31.6 3.4 1.6 69.2 38.7 31.4 66.0 24.5 4.7 17.8 0.0 109.0 44.0 1.4 6.4 3.4 0.6 0.2 1.8 1.4 0.5 5.0 60.7 7.3 0.4 0.2 7.7 0.0 0.8 7.0 13.9 1.0 9.5 15.8 9.0 15.2 12.3 45.3 5.3 0.4 11.8 10.2 4.5 43.1 9.4 30.9 9.9 12.3 13.8 7.5 27.6 19.6 11.5 4.0 3.1 10.0 114.7 3.1 22.1 0.2 96.2 12.8 3.6 3.6 2.9 4.7 3.6 3.7 4.6 3.1 4.0 3.5 3.9 4.3 10.3 57.7 13.8 40.1 12.8 45.9 109.7 53.1 39.9 0.0 5.5 9.5 3.5 12.8 27.5 9.2 0.0 0.4 16.3 24.9 0.0 6.3 11.3 9.2 22.3 8.9 8.4 9.5 8.8 4.3 0.2 35.4 8.6 15.5 3.8 4.9 2.2 19.3 5.5 1.7 2.8 14.4 8.2 7.0 31.7 4.9 19.0 17.7 12.4 17.8 20.9 14.5 10.3 8.0 0.7 6.5 8.7 13.9 32.2 46.0 15.6 14.4 26.3 0.7 6.6 26.8 29.1 11.3 1.1 28.5 43.9 0.4 48.4 11.8 24.4 30.0 FAT1 "CDHF7, CDHR8, FAT" ENSG00000083857 "FAT atypical cadherin 1" Q14517 4 186587794-186726722 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 119.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 285.7;LHCN-M2: 206.7" "Low region specificity" "Detected in all" "HPA001869, HPA023882" Enhanced "Intracellular and membrane" NA NA 4600000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA001869: AB_1078818, HPA023882: AB_1848429" "unprognostic (1.98e-1)" "unprognostic (4.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.86e-1)" "unprognostic (1.53e-2)" "unprognostic (5.82e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.15e-3)" "unprognostic (6.80e-2)" "unprognostic (3.57e-2)" "unprognostic (8.03e-3)" "unprognostic (9.41e-2)" "unprognostic (6.25e-3)" "unprognostic (4.27e-2)" 20.1 1.3 14.5 7.2 20.2 0.8 21.9 31.1 12.4 20.0 119.2 35.0 25.9 23.4 16.0 13.3 9.8 23.5 24.8 14.3 27.0 22.1 10.0 12.9 2.4 40.1 42.3 10.4 12.6 11.4 9.7 17.0 24.4 21.4 31.4 3.4 18.7 24.2 3.5 17.5 24.2 25.7 22.1 2.2 16.8 9.7 22.2 6.0 14.6 3.9 4.4 32.0 11.0 22.0 22.2 83.5 80.9 0.3 79.1 94.5 19.9 110.9 181.9 52.8 33.5 50.0 49.0 0.0 26.0 285.7 34.1 40.4 32.0 136.7 71.6 0.2 13.2 0.0 30.5 50.8 39.4 37.3 29.2 34.5 48.4 98.7 63.5 72.4 1.1 44.8 0.6 0.0 206.7 27.1 66.2 0.1 18.1 42.2 13.9 0.3 22.3 1.8 79.2 79.0 8.6 32.3 19.2 32.2 12.7 54.9 0.3 13.3 23.8 149.8 57.9 2.0 69.8 0.4 0.2 0.5 34.1 0.1 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 20.2 31.1 12.4 14.3 27.0 40.1 42.3 24.4 22.1 22.2 22.0 6.1 16.0 6.7 55.2 0.3 85.0 27.2 115.4 27.3 5.2 26.5 27.6 27.6 38.6 40.7 53.3 0.0 1.6 0.2 71.2 5.9 25.2 0.7 25.7 17.2 5.0 14.5 0.0 5.8 26.5 3.6 28.8 54.0 29.6 16.5 75.0 1.1 26.1 0.4 0.0 30.3 56.4 18.3 0.8 7.3 0.9 14.6 1.7 12.4 5.6 0.0 4.5 0.0 14.1 12.4 30.3 30.0 37.2 0.2 55.8 78.2 26.7 37.0 0.4 39.5 23.1 65.1 1.5 10.4 10.2 46.9 1.6 1.9 11.7 45.1 38.9 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 92.7;Endometrial stromal cells: 84.4;Fibroblasts: 458.4;Leydig cells: 170.9;Peritubular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 384.0;fHDF/TERT166: 264.3;HMC-1: 311.6;HSkMC: 221.9;U-2197: 139.2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" 157.3 7.6 5.9 12.7 7.7 1.0 97.3 5.2 9.0 63.4 6.4 32.7 6.2 31.1 3.2 42.4 26.8 46.2 292.8 7.0 4.9 8.7 3.7 29.2 8.4 5.3 5.3 5.8 8.6 3.0 2.3 80.3 4.8 29.1 11.8 0.6 39.4 8.8 47.7 72.5 19.8 14.7 4.1 6.0 22.3 46.7 6.9 14.2 63.7 48.9 5.6 79.6 56.7 4.4 0.0 1.4 50.9 0.0 384.0 51.7 23.8 124.9 98.2 122.4 80.4 8.1 0.3 0.0 5.9 264.3 0.2 0.2 0.0 0.5 22.9 0.1 0.1 100.7 1.9 0.0 26.0 0.2 311.6 221.9 2.0 19.3 0.0 0.2 0.0 8.6 0.8 0.9 0.6 0.3 5.2 0.6 12.2 0.0 0.7 0.2 0.0 0.5 0.9 0.1 3.0 2.4 0.5 90.3 0.1 13.6 0.2 0.3 0.1 0.1 0.1 139.2 0.1 0.2 0.0 0.0 1.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.2 6.7 1.3 0.0 3.7 0.0 0.2 0.0 0.5 0.0 0.9 5.9 7.7 5.2 9.0 7.0 4.9 5.3 5.3 4.8 4.1 6.9 4.4 92.7 0.0 1.5 1.6 3.6 30.8 0.8 10.5 2.2 0.0 1.7 1.9 8.8 0.0 12.3 7.3 2.1 7.8 1.9 0.1 0.0 0.0 3.8 2.9 84.4 43.8 0.0 1.7 0.6 0.2 4.8 458.4 6.1 2.7 23.6 0.6 47.8 0.4 3.6 0.0 0.6 0.0 0.0 1.9 49.8 12.1 170.9 4.5 39.2 26.2 0.3 1.2 0.0 30.7 0.3 0.3 0.0 227.2 1.6 1.2 2.7 0.1 1.4 0.4 13.1 29.7 26.4 3.4 13.5 2.0 28.8 6.2 5.3 0.2 0.0 1.1 FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Fibroblasts: 209.4;Leydig cells: 626.6;Peritubular cells: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "ASC diff: 457.1;ASC TERT1: 234.6;BJ: 202.0;BJ hTERT+: 202.5;fHDF/TERT166: 394.6;HSkMC: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" 182.2 73.4 10.7 17.7 12.8 7.5 110.4 7.4 12.5 124.9 15.7 80.3 19.1 178.4 40.0 26.8 143.0 130.2 211.1 9.4 8.6 108.4 29.3 164.8 25.5 15.5 10.9 107.3 46.4 16.8 14.5 67.0 14.2 49.0 20.6 0.6 55.8 70.9 30.4 66.9 52.7 88.7 13.1 130.9 68.9 35.6 12.7 21.8 79.5 36.0 15.7 117.5 93.3 7.5 0.0 1.6 0.2 0.0 457.1 234.6 22.5 202.0 202.5 5.8 4.5 4.7 0.0 0.0 4.2 394.6 0.6 0.1 9.8 1.0 1.0 0.0 2.3 0.4 4.7 0.0 74.2 0.0 0.1 216.6 0.4 3.9 14.1 2.8 10.4 0.1 0.0 0.1 25.3 0.4 0.5 0.5 0.5 0.0 0.5 0.4 30.2 0.2 1.2 0.1 0.2 0.1 12.3 0.7 2.6 7.0 2.9 0.3 1.9 3.2 6.6 3.8 0.1 0.1 0.0 0.2 0.4 0.0 0.0 6.6 0.1 2.2 0.8 0.2 0.5 0.0 0.3 0.1 0.0 0.1 1.1 1.8 2.5 0.0 0.2 0.0 0.1 0.4 10.7 12.8 7.4 12.5 9.4 8.6 15.5 10.9 14.2 13.1 12.7 7.5 31.4 83.3 13.1 0.0 2.1 9.2 2.4 7.1 1.8 0.0 11.2 9.3 5.2 0.0 11.5 5.5 0.0 2.5 2.5 0.1 5.9 4.7 5.9 13.3 67.4 15.2 0.0 0.4 2.6 4.7 2.5 209.4 2.0 12.0 2.5 1.8 34.2 0.4 7.8 0.0 3.6 0.1 18.3 2.5 18.4 27.5 626.6 5.8 21.4 15.9 1.6 0.0 8.2 5.0 2.3 2.2 0.0 794.8 0.7 1.3 0.0 32.5 21.4 0.0 6.6 28.0 14.5 3.0 2.8 1.3 8.7 3.7 15.5 3.5 0.4 1.2 FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.4;Fibroblasts: 16.6;Inhibitory neurons: 30.7;Melanocytes: 17.8;Skeletal myocytes: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.4;naive CD4 T-cell: 29.5;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Cell line enhanced" "Detected in many" "AF22: 24.5;BJ hTERT+: 17.7;hTERT-RPE1: 12.8;SCLC-21H: 15.8;SH-SY5Y: 12.6;U-2197: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" NA NA 310000 "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA034992: AB_10601469" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.88e-2)" "unprognostic (4.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.70e-3)" "unprognostic (4.34e-2)" "unprognostic (4.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (7.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.35e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.33e-2)" 6.5 4.0 0.8 4.3 0.6 0.7 7.8 4.0 6.4 10.3 0.4 1.8 1.1 4.8 2.8 1.9 7.1 3.4 2.5 2.1 3.8 1.5 5.2 2.7 9.8 9.2 4.4 1.4 2.4 6.9 12.2 3.2 9.7 3.3 1.3 2.5 2.5 3.1 1.4 5.5 2.9 2.2 2.2 5.6 3.0 0.5 4.1 8.6 10.7 2.5 6.0 2.5 7.5 1.1 0.0 0.1 24.5 0.0 2.6 1.9 0.1 5.5 17.7 5.9 9.2 0.0 0.2 0.0 0.1 8.3 1.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.9 1.1 1.2 0.0 0.0 1.9 0.1 9.9 0.0 12.8 1.4 0.3 0.0 0.0 2.1 0.0 0.7 0.1 0.6 0.0 0.5 0.0 0.0 6.6 0.3 0.0 15.8 12.6 0.1 0.1 0.7 0.1 0.7 0.2 5.2 0.8 0.7 25.4 0.8 0.0 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.0 0.4 0.0 1.3 0.0 34.4 0.4 0.0 0.0 29.5 1.0 0.0 0.0 0.0 1.0 36.5 6.2 0.8 0.6 4.0 6.4 2.1 3.8 9.2 4.4 9.7 2.2 4.1 1.1 1.4 3.2 0.5 0.3 0.7 4.5 1.0 0.3 0.0 3.8 1.0 2.4 1.1 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 1.7 1.2 5.9 2.6 0.0 0.0 14.4 0.2 10.1 16.6 0.0 1.2 1.3 0.7 0.4 2.2 0.5 3.3 30.7 0.0 0.0 0.0 4.0 3.6 0.3 0.4 17.8 1.9 0.0 2.3 0.0 6.6 0.9 0.6 0.0 5.3 0.1 0.4 0.1 0.5 0.3 7.6 6.6 19.3 7.8 0.1 0.4 0.1 3.8 1.5 7.7 0.2 0.0 0.3 FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.9;placenta: 76.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 132.4;Fibroblasts: 388.5;Leydig cells: 236.1;Oligodendrocytes: 218.7;Peritubular cells: 227.2;Skeletal myocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 215.1;ASC TERT1: 460.7;fHDF/TERT166: 420.8;HSkMC: 251.3;hTERT-RPE1: 211.1;U-138 MG: 206.9;U-2197: 305.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved Cytosol "Secreted to blood" NA NA 520000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" 60.9 4.4 1.4 14.5 5.4 3.4 13.7 2.8 2.8 36.0 9.5 8.3 3.8 15.2 6.3 12.6 12.2 27.3 23.5 0.8 2.0 2.7 2.9 10.0 3.7 5.2 6.0 28.4 3.3 3.0 2.5 76.7 3.7 8.0 11.7 1.3 4.6 13.2 4.5 5.7 6.6 35.7 2.3 6.4 6.0 7.1 4.7 2.9 18.6 21.2 3.5 18.8 9.9 5.0 0.1 5.2 19.8 22.4 215.1 460.7 0.2 175.8 62.9 51.1 32.4 0.1 0.3 0.1 7.9 420.8 0.4 0.7 3.9 0.6 45.9 20.7 1.2 2.0 88.5 0.2 120.7 0.8 0.3 251.3 0.1 135.9 15.6 211.1 55.5 1.6 0.0 0.4 55.6 0.0 1.5 0.2 4.0 0.2 7.1 0.1 17.0 0.2 5.9 0.5 0.2 12.9 0.0 2.2 0.1 15.3 0.2 1.4 106.8 206.9 6.2 305.8 37.6 1.2 1.0 0.0 138.9 0.3 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 5.4 2.8 2.8 0.8 2.0 5.2 6.0 3.7 2.3 4.7 5.0 50.0 0.0 1.3 34.9 0.4 25.6 0.8 1.5 0.6 6.1 1.3 3.4 14.2 0.0 5.8 12.9 0.0 132.4 0.4 0.0 0.0 0.2 8.7 4.2 105.2 36.1 0.0 5.5 82.3 0.6 40.8 388.5 3.1 2.0 1.3 22.5 34.6 0.6 15.3 0.0 123.5 0.0 0.0 0.8 39.0 22.8 236.1 5.7 42.7 30.0 2.3 0.8 0.0 76.9 218.7 1.7 0.0 227.2 1.7 0.7 0.1 0.6 3.3 0.2 26.3 139.5 55.8 3.3 3.4 0.8 20.6 65.8 4.3 51.3 0.0 0.2 FBN2 "CCA, DA9" ENSG00000138829 "Fibrillin 2" P35556 5 128257909-128659185 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "placenta: 81.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 298.1;Syncytiotrophoblasts: 163.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Lineage enriched" "Detected in single" 5 "monocytes: 2.2" "Cell line enhanced" "Detected in many" "HHSteC: 134.1;HSkMC: 94.3;hTERT-HME1: 215.2;HUVEC TERT2: 122.3" "Region enhanced" "Detected in single" "olfactory bulb: 2.0" "Low region specificity" "Detected in many" "HPA012853, CAB026401" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 11000000 "Cluster 14: Monocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Nucleoplasm "CAB026401: , HPA012853: AB_1848588" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (7.29e-3)" "unprognostic (1.79e-3)" "unprognostic (6.74e-2)" "unprognostic (2.33e-1)" "unprognostic (4.92e-3)" "unprognostic (9.41e-2)" "unprognostic (1.06e-2)" "unprognostic (4.66e-1)" "unprognostic (1.12e-1)" "unprognostic (8.69e-2)" "unprognostic (8.60e-5)" "unprognostic (1.04e-2)" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (7.41e-5)" 0.1 5.1 0.4 0.8 0.5 3.1 0.2 0.0 0.3 2.2 3.0 0.8 0.3 1.7 0.1 0.1 0.4 0.3 5.5 0.2 0.6 0.1 0.1 0.2 0.5 1.1 1.9 0.5 0.2 0.0 0.8 81.9 0.5 0.8 1.2 0.9 0.3 0.4 0.2 0.2 0.4 1.3 0.5 0.4 0.8 7.4 0.8 0.2 0.5 0.4 0.9 0.5 0.7 0.3 0.0 16.4 58.2 0.0 9.4 16.6 11.8 62.8 0.0 56.0 41.8 0.2 0.0 0.0 0.1 85.5 0.0 9.2 37.6 9.8 52.7 0.1 13.8 0.0 27.3 0.2 134.1 8.4 0.0 94.3 5.3 24.1 215.2 17.9 122.3 0.0 0.0 0.0 35.8 0.1 0.0 3.4 24.5 0.0 18.2 19.2 18.1 0.0 0.1 0.0 0.5 0.0 0.4 0.2 0.6 48.0 0.0 18.7 0.0 22.1 41.9 66.8 0.3 0.0 0.0 0.0 6.9 0.0 23.8 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.2 0.6 1.1 1.9 0.5 0.5 0.8 0.3 0.1 0.0 0.5 1.6 0.2 0.0 0.1 1.2 0.6 0.0 0.3 0.3 12.7 0.0 1.4 0.0 0.0 298.1 0.0 0.0 0.0 0.3 3.8 10.0 3.9 1.0 0.0 0.0 1.1 0.0 24.3 8.8 0.0 4.7 0.0 0.1 0.0 0.0 34.0 0.0 50.5 0.0 0.0 10.7 0.4 7.2 1.2 2.7 1.8 1.9 6.2 3.8 0.0 17.6 1.5 0.1 0.0 2.2 0.0 2.0 0.0 0.2 1.6 0.1 6.6 0.1 3.5 10.7 3.5 0.1 0.4 163.5 0.1 8.4 0.1 0.1 FBXL18 "Fbl18, FLJ11467" ENSG00000155034 "F-box and leucine rich repeat protein 18" Q96ME1 7 5431335-5513809 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036049 Approved Nucleoplasm,Cytosol No No "Cluster 42: Non-specific - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "HPA036049: AB_2674918" "unprognostic (2.86e-3)" "prognostic unfavorable (7.88e-4)" "unprognostic (1.26e-2)" "unprognostic (8.73e-3)" "unprognostic (1.72e-2)" "unprognostic (3.70e-1)" "unprognostic (3.98e-4)" "unprognostic (1.50e-2)" "unprognostic (2.74e-1)" "unprognostic (1.51e-3)" "unprognostic (1.04e-2)" "unprognostic (3.69e-1)" "unprognostic (8.28e-4)" "unprognostic (1.46e-1)" "unprognostic (1.64e-1)" "unprognostic (7.30e-4)" "unprognostic (1.73e-3)" 2.3 1.9 6.8 2.0 7.0 2.7 1.1 3.2 14.2 1.0 1.8 1.3 1.7 1.5 1.1 2.0 1.1 0.9 1.9 10.2 4.3 1.3 1.2 1.3 1.9 5.3 2.5 1.2 2.6 2.1 1.4 1.3 2.6 1.4 0.9 1.4 2.0 1.2 3.6 3.8 1.5 1.3 0.7 1.5 1.6 1.6 5.8 1.4 1.4 2.0 1.6 1.3 1.0 5.1 11.0 15.2 3.7 9.7 5.7 4.2 6.9 6.5 2.9 4.0 3.9 12.0 7.4 5.2 7.5 4.0 7.4 17.3 4.9 14.7 2.8 3.5 6.3 2.8 10.7 4.7 4.2 4.9 4.3 4.3 7.9 6.4 3.6 3.8 5.0 3.0 8.0 3.5 3.7 16.4 3.0 5.3 13.7 5.1 12.1 6.8 7.8 3.6 4.0 6.1 7.9 12.2 10.2 18.1 3.5 4.5 17.9 4.4 11.4 12.9 16.6 10.1 9.9 5.2 7.5 3.8 7.1 7.1 16.1 6.3 2.1 0.9 1.4 2.1 1.3 1.3 0.9 1.4 1.6 1.8 1.0 1.2 5.0 2.3 2.9 1.4 1.2 1.5 6.8 7.0 3.2 14.2 10.2 4.3 5.3 2.5 2.6 0.7 5.8 5.1 4.8 6.4 4.8 6.2 2.6 2.5 3.0 0.9 1.2 9.7 3.9 9.1 5.3 2.8 5.8 0.0 4.2 3.9 5.5 4.8 0.0 2.4 1.5 7.6 3.5 2.8 4.8 0.4 10.8 2.6 2.7 2.7 4.6 7.3 2.5 3.0 2.5 1.8 1.5 1.7 8.5 1.9 4.1 3.5 2.9 0.5 1.5 2.4 0.0 7.5 3.2 4.7 5.2 4.0 7.8 2.2 2.1 0.7 1.4 2.4 2.4 1.2 3.2 6.6 0.0 4.7 3.0 2.7 4.9 2.4 3.3 2.2 2.9 1.5 4.8 1.8 FBXL19 "CXXC11, DKFZp434K0410, Fbl19, JHDM1C" ENSG00000099364 "F-box and leucine rich repeat protein 19" Q6PCT2 16 30923055-30948783 "Predicted intracellular proteins" "Ubl conjugation pathway" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074250 Approved Nucleoplasm NA No "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA074250: " "unprognostic (1.37e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.03e-1)" "unprognostic (3.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (3.54e-4)" "unprognostic (3.61e-2)" "unprognostic (2.52e-1)" "unprognostic (2.89e-1)" "unprognostic (1.48e-1)" "unprognostic (6.95e-3)" "unprognostic (1.37e-3)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.45e-2)" "unprognostic (2.38e-2)" 5.4 7.7 16.5 9.8 14.8 8.3 5.5 4.4 27.9 8.7 1.9 8.6 10.4 8.5 4.0 16.5 7.3 8.5 5.6 16.8 10.1 11.5 4.3 5.8 9.7 9.4 8.6 8.4 6.7 7.2 11.4 10.1 9.1 9.9 3.8 8.5 8.9 5.4 4.8 12.7 8.8 4.6 3.1 9.9 8.7 30.0 12.4 10.0 7.9 4.0 5.1 8.5 9.6 14.4 17.5 46.0 44.7 35.6 8.0 8.1 38.6 24.2 12.3 18.3 17.2 24.8 23.9 27.1 27.4 14.4 14.2 24.3 35.9 25.8 14.0 76.3 110.0 30.0 84.0 36.5 9.9 33.5 69.9 8.3 20.4 22.6 16.0 15.9 30.0 37.7 80.0 26.3 10.3 46.9 36.4 46.2 44.4 13.0 15.5 73.1 14.2 27.0 17.7 23.6 29.6 56.3 8.5 53.0 13.7 25.1 32.5 34.8 30.0 20.2 26.1 13.5 17.1 23.1 20.4 16.9 24.7 49.0 29.9 0.0 0.4 0.5 0.3 0.2 0.3 0.5 0.1 0.1 0.2 0.2 0.0 0.3 0.5 0.9 0.0 0.7 0.2 0.1 16.5 14.8 4.4 27.9 16.8 10.1 9.4 8.6 9.1 3.1 12.4 14.4 3.4 0.0 1.1 4.9 1.5 8.3 2.4 2.5 2.8 6.1 6.8 4.1 1.5 4.3 2.9 3.7 12.5 5.7 4.0 8.9 0.0 6.1 5.6 3.8 4.7 5.0 2.4 1.3 4.5 7.1 5.4 3.1 3.6 6.0 0.0 8.9 3.6 2.3 5.2 1.7 5.0 6.5 2.0 2.8 3.9 6.5 1.5 3.4 0.0 3.7 3.3 2.8 4.1 3.0 2.1 8.6 4.1 2.6 1.7 6.4 3.3 5.1 1.8 6.0 6.6 2.2 3.5 4.7 2.9 5.4 8.9 9.3 2.0 4.9 8.5 6.5 FBXO45 Fbx45 ENSG00000174013 "F-box protein 45" P0C2W1 3 196568611-196589059 "Predicted intracellular proteins" "Neurogenesis, Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040730 Uncertain Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA040730: AB_10959311" "unprognostic (7.17e-3)" "unprognostic (1.14e-1)" "unprognostic (8.37e-2)" "unprognostic (1.01e-2)" "unprognostic (8.14e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.61e-5)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.13e-2)" "unprognostic (9.48e-3)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.16e-5)" "prognostic unfavorable (4.93e-5)" "unprognostic (5.18e-2)" "unprognostic (1.66e-1)" "unprognostic (6.93e-2)" "unprognostic (1.65e-1)" 5.1 4.2 10.7 6.1 11.5 13.9 7.3 11.8 14.8 4.5 6.8 6.9 5.3 4.7 3.0 8.9 3.6 4.4 3.6 11.0 10.9 3.7 6.9 4.5 6.7 10.7 10.9 5.0 4.6 7.2 3.1 5.4 10.4 5.1 7.0 8.2 4.0 4.3 13.8 12.7 5.1 5.0 11.6 5.1 5.5 12.2 11.5 8.8 3.7 11.5 10.0 6.8 5.0 11.7 45.5 8.5 17.6 22.4 11.6 11.4 20.9 19.7 9.0 15.3 15.6 23.9 15.1 19.1 33.1 12.8 22.8 19.0 33.9 22.5 28.1 27.7 15.3 34.8 15.5 15.1 11.1 46.9 17.1 5.8 24.9 17.3 31.8 8.0 16.9 30.5 42.4 39.2 17.2 45.3 27.5 21.9 27.4 40.3 32.5 23.1 23.0 46.2 12.9 18.3 35.6 24.4 21.4 36.8 23.5 15.4 63.3 31.1 16.8 17.7 19.1 25.7 53.8 38.3 68.5 52.6 15.4 59.6 17.3 1.3 0.9 1.1 0.8 0.9 1.4 0.5 0.8 0.5 1.2 0.8 0.8 0.9 0.4 0.6 1.1 1.4 1.6 0.4 10.7 11.5 11.8 14.8 11.0 10.9 10.7 10.9 10.4 11.6 11.5 11.7 10.2 12.8 4.1 6.5 6.6 9.8 10.2 5.6 4.6 20.1 10.5 7.7 10.8 4.3 4.2 3.7 14.6 2.6 11.5 7.9 0.0 4.4 15.5 8.0 12.9 8.0 17.4 6.1 13.8 7.7 4.6 7.8 10.7 8.8 1.3 6.9 7.9 9.9 5.8 13.5 15.0 8.2 4.1 9.1 11.0 18.9 5.6 7.6 5.4 8.4 8.3 9.3 4.1 6.6 12.4 8.3 4.8 6.4 8.0 14.8 4.0 3.4 6.8 10.7 0.0 10.5 7.5 32.4 24.4 9.4 13.5 1.9 8.2 7.1 9.8 14.5 FBXW7 "AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10" ENSG00000109670 "F-box and WD repeat domain containing 7" Q969H0 4 152320544-152536092 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 201.8;Excitatory neurons: 529.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 23.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013793, CAB029987" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "CAB013793: AB_2533451, CAB029987: AB_2246842" "unprognostic (3.32e-1)" "unprognostic (9.02e-2)" "unprognostic (1.84e-2)" "unprognostic (3.08e-2)" "unprognostic (3.87e-1)" "unprognostic (1.36e-3)" "unprognostic (4.37e-1)" "unprognostic (1.94e-1)" "unprognostic (8.28e-2)" "unprognostic (3.29e-1)" "unprognostic (5.32e-3)" "unprognostic (3.19e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (3.38e-2)" "unprognostic (1.41e-1)" "unprognostic (5.49e-3)" "unprognostic (2.17e-3)" 14.2 9.5 37.9 15.0 43.1 19.8 14.2 54.3 66.9 8.7 6.7 9.5 7.8 8.6 24.3 14.3 15.6 9.2 24.7 48.2 23.0 6.7 11.2 11.4 16.1 17.1 20.9 9.1 12.8 7.8 9.2 9.4 18.1 7.8 10.3 18.0 11.8 7.5 26.0 63.1 10.4 9.1 11.8 16.2 13.0 22.8 29.4 14.7 10.3 19.7 20.3 11.9 10.7 47.4 9.8 8.0 19.1 14.2 12.2 9.4 16.2 13.4 12.9 8.5 8.1 15.7 12.0 24.7 3.9 13.7 6.5 5.2 16.9 30.9 12.1 16.2 8.0 11.9 10.7 10.9 12.7 29.2 10.6 14.8 45.7 15.2 24.4 8.4 15.2 20.5 19.2 25.7 10.8 13.7 34.9 10.6 9.7 8.0 6.1 32.2 8.0 5.3 9.8 17.0 12.7 10.2 8.5 11.3 7.5 21.6 6.4 12.6 15.6 11.3 12.6 5.4 8.2 79.0 47.5 24.4 9.4 9.2 8.3 23.5 2.7 1.6 4.0 3.0 2.7 2.8 3.1 2.7 1.6 1.8 3.4 2.5 4.8 7.1 2.2 2.1 2.9 1.3 37.9 43.1 54.3 66.9 48.2 23.0 17.1 20.9 18.1 11.8 29.4 47.4 29.5 9.6 22.9 80.0 48.1 201.8 36.5 29.9 120.1 74.9 32.1 30.9 61.8 12.8 15.1 9.2 31.3 10.9 54.7 22.2 3.9 14.3 17.4 37.7 37.3 36.1 14.5 30.1 529.6 13.5 39.9 27.2 21.4 61.6 15.8 19.1 17.9 18.3 10.5 11.8 186.5 16.4 32.6 18.8 47.0 10.2 15.2 33.7 28.4 172.4 28.0 37.0 35.0 102.5 99.8 18.7 18.2 11.3 174.5 36.3 8.9 7.5 11.9 41.4 13.1 33.2 25.5 74.1 87.2 57.0 174.9 31.2 46.2 18.7 14.9 70.5 FCAR CD89 ENSG00000186431 "Fc fragment of IgA receptor" P24071 19 54874235-54891420 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "IgA-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 26.1;lung: 10.5;lymphoid tissue: 13.5" "Group enriched" "Detected in some" 6 "Kupffer cells: 12.8;Macrophages: 18.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "classical monocyte: 1.2;neutrophil: 4.0" "Group enriched" "Detected in many" 27 "granulocytes: 4.0;monocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA014050 Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA014050: AB_1846338" "unprognostic (1.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.30e-1)" "unprognostic (4.71e-3)" "unprognostic (3.46e-1)" "unprognostic (2.02e-1)" "unprognostic (7.99e-2)" "unprognostic (1.54e-2)" "unprognostic (1.59e-2)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (7.05e-2)" "unprognostic (4.19e-6)" "unprognostic (9.23e-2)" "unprognostic (8.10e-3)" "unprognostic (8.04e-3)" "unprognostic (9.81e-2)" 4.5 0.3 0.0 1.0 0.0 26.1 0.7 0.0 0.3 0.2 0.0 0.6 0.0 0.2 0.0 0.3 3.4 0.0 1.5 0.0 0.0 0.5 1.7 10.5 0.0 0.1 0.0 0.3 0.2 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.4 0.1 0.4 0.1 0.0 13.5 0.8 0.1 0.0 0.0 0.5 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.3 0.1 0.3 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 12.8 0.3 0.0 0.0 18.0 0.0 1.0 2.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.7 0.5 0.0 0.3 0.3 0.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.1 FCER2 "CD23, CD23A, CLEC4J, FCE2" ENSG00000104921 "Fc fragment of IgE receptor II" P06734 19 7688758-7702146 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "IgE-binding protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 42.2" "Cell type enriched" "Detected in some" 16 "B-cells: 157.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.1" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in many" 24 "memory B-cell: 200.9;naive B-cell: 496.2" "Lineage enriched" "Detected in many" 34 "B-cells: 496.2" "Cell line enriched" "Detected in some" 14 "HDLM-2: 449.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002624, HPA008928, HPA067430" Enhanced "Secreted to blood" NA NA 240000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "CAB002624: , HPA008928: AB_1846285, HPA067430: " "unprognostic (3.20e-4)" "unprognostic (1.87e-3)" "unprognostic (1.95e-2)" "unprognostic (2.44e-2)" "unprognostic (4.77e-2)" "unprognostic (1.77e-3)" "unprognostic (1.64e-1)" "unprognostic (1.89e-3)" "unprognostic (2.71e-1)" "unprognostic (1.88e-1)" "unprognostic (2.04e-2)" "unprognostic (8.55e-2)" "unprognostic (2.46e-4)" "unprognostic (2.99e-1)" "unprognostic (1.80e-1)" "unprognostic (4.89e-2)" "unprognostic (5.17e-2)" 4.8 0.1 0.0 17.4 0.0 5.2 1.2 0.2 1.3 0.4 0.0 1.8 2.8 0.1 0.1 0.4 0.3 1.1 0.5 0.3 0.0 0.3 0.5 0.6 39.5 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.0 0.1 1.9 0.0 1.8 0.1 0.3 0.4 9.7 0.2 0.0 38.4 2.2 0.4 0.0 6.3 0.6 0.1 42.2 1.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 449.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 0.1 32.7 0.0 0.5 4.2 0.3 0.0 14.7 0.1 200.9 0.2 0.0 4.4 496.2 0.3 0.1 1.5 0.3 4.4 0.6 0.2 21.6 0.0 0.0 0.2 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 157.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.1 0.0 1.2 0.0 0.1 0.0 0.0 1.3 1.7 0.0 0.0 9.4 1.8 1.0 0.9 0.0 2.1 0.0 0.1 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 1.2 1.2 0.0 0.0 FCGBP FC(GAMMA)BP ENSG00000275395 "Fc fragment of IgG binding protein" 19 39863323-39934626 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 206.9;salivary gland: 85.4;stomach 1: 85.5;thyroid gland: 99.9" "Cell type enriched" "Detected in many" 9 "Intestinal goblet cells: 6081.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 63.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.6;Daudi: 1.8;JURKAT: 1.7;MOLT-4: 1.8;RH-30: 7.1" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: AB_1078838, HPA003564: AB_2231648" "unprognostic (1.65e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-3)" "unprognostic (1.77e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.28e-5)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.36e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (9.70e-6)" "unprognostic (9.44e-2)" "unprognostic (3.03e-2)" "unprognostic (5.92e-3)" "unprognostic (8.60e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.08e-1)" 5.9 10.0 5.1 14.0 7.2 0.4 3.2 4.0 8.4 56.4 15.0 206.9 68.7 1.2 0.6 4.6 9.8 49.2 2.9 5.6 6.8 11.3 1.0 1.9 0.9 20.1 10.6 3.7 4.9 0.5 3.4 2.9 11.1 3.8 67.7 0.6 85.4 1.4 0.4 14.8 148.7 2.6 5.9 1.5 85.5 2.9 14.0 1.5 99.9 0.0 0.7 3.4 1.6 12.0 0.0 4.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.2 0.0 0.1 1.8 0.6 0.1 1.5 0.3 0.1 7.1 1.6 0.1 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.5 0.0 0.3 0.1 0.0 0.0 0.1 5.1 7.2 4.0 8.4 5.6 6.8 20.1 10.6 11.1 5.9 14.0 12.0 0.6 3.2 5.1 2.6 4.6 3.7 1.9 15.8 1.2 1.1 1.3 3.4 2.8 70.1 60.0 25.8 0.0 0.7 1.8 622.2 0.0 5.2 7.2 4.2 0.3 26.7 81.1 0.0 0.6 0.9 0.4 1.9 552.0 4.0 15.9 0.4 0.7 1.3 44.0 0.0 0.4 6081.9 2.0 30.2 12.6 9.2 0.9 21.6 8.8 15.9 0.9 0.4 1.0 0.5 0.2 3.9 253.6 0.0 2.1 13.8 413.5 1.2 11.0 2.0 59.2 0.5 1.1 0.5 2.4 0.4 6.8 0.4 5.6 0.9 191.4 164.1 FCGR1B CD64b ENSG00000198019 "Fc fragment of IgG receptor Ib" Q92637 1 121087345-121097161 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 86.5;Kupffer cells: 51.5;Late spermatids: 14.6;Macrophages: 36.6;monocytes: 16.4;Sertoli cells: 19.7" "Cancer enriched" "Detected in single" 4 "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 31.2;neutrophil: 36.3" "Group enriched" "Detected in many" 4 "granulocytes: 36.3;monocytes: 31.2" "Group enriched" "Detected in some" 6 "NB-4: 19.8;THP-1: 73.9" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (3.21e-2)" "unprognostic (4.35e-2)" "unprognostic (1.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (9.60e-2)" "unprognostic (1.56e-2)" "unprognostic (6.42e-2)" "unprognostic (3.10e-2)" "unprognostic (8.17e-2)" "unprognostic (1.91e-1)" "unprognostic (3.65e-1)" "unprognostic (3.24e-10)" "unprognostic (8.99e-2)" "unprognostic (2.85e-2)" "unprognostic (7.86e-3)" "unprognostic (8.93e-2)" 5.0 3.0 4.4 18.9 4.5 6.6 1.8 4.5 7.8 1.0 3.7 0.7 0.5 0.7 51.5 0.7 0.8 1.9 1.1 4.6 4.7 1.4 1.7 6.8 2.2 6.1 5.7 0.6 2.6 0.7 1.0 11.0 6.2 0.8 0.8 0.8 0.9 0.6 0.4 0.2 0.7 5.8 6.0 7.2 0.9 0.7 6.2 0.4 2.1 0.1 0.3 4.0 0.4 6.4 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 5.9 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 19.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.1 0.0 0.3 1.0 73.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 31.2 0.6 0.0 19.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 36.3 0.0 12.4 0.3 0.0 8.8 4.4 4.5 4.5 7.8 4.6 4.7 6.1 5.7 6.2 6.0 6.2 6.4 0.4 0.0 2.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.1 0.6 2.2 0.0 0.6 0.0 2.1 0.8 0.1 0.1 0.0 0.0 7.7 0.2 0.2 2.0 0.0 0.8 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.4 0.4 0.3 86.5 3.3 0.1 0.0 0.0 51.5 4.1 14.6 1.2 36.6 0.0 11.2 16.4 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.4 19.7 0.6 0.1 0.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.1 FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Cell type enhanced" "Detected in many" "dendritic cells: 333.4;Hofbauer cells: 193.1;Kupffer cells: 807.9;Macrophages: 300.0;NK-cells: 579.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" 52.9 41.9 18.4 99.8 20.4 27.3 14.7 19.3 27.2 8.2 26.5 12.5 5.8 5.9 5.9 4.9 9.1 24.5 22.3 16.9 22.0 7.9 111.5 206.3 37.1 37.7 27.9 6.6 7.8 13.6 11.3 71.0 30.6 6.9 12.6 6.9 14.7 7.6 3.3 2.2 5.7 68.4 31.7 306.8 6.8 7.7 28.8 9.3 7.0 4.3 3.9 32.5 3.5 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 26.2 9.6 513.6 1763.5 4.9 3.7 4.7 205.9 175.8 1.4 3.0 184.0 1169.8 136.2 3948.7 4.6 2.6 734.1 18.4 20.4 19.3 27.2 16.9 22.0 37.7 27.9 30.6 31.7 28.8 39.8 2.7 22.4 24.6 0.7 6.5 0.5 0.1 0.0 0.0 0.2 1.4 3.4 0.7 8.6 10.5 3.7 2.1 1.2 333.4 0.0 0.0 0.2 1.4 0.1 0.0 18.9 0.0 16.4 0.0 0.0 1.4 3.9 0.0 0.1 18.9 0.1 8.6 5.3 193.1 0.0 0.1 0.1 0.0 807.9 7.4 3.7 0.3 300.0 0.0 20.6 77.2 0.1 579.9 0.0 0.1 0.0 0.0 0.0 22.1 0.0 0.0 0.8 5.8 1.5 19.7 1.1 0.4 0.0 0.5 0.2 0.0 2.1 88.0 0.0 0.0 0.3 FCGRT "alpha-chain, FCRN" ENSG00000104870 "Fc fragment of IgG receptor and transporter" P55899 19 49506816-49526428 "Predicted intracellular proteins, Predicted membrane proteins" "IgG-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1362.6;Kupffer cells: 877.7;Paneth cells: 883.9;Proximal enterocytes: 1787.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2346.7" "Group enriched" "Detected in all" 17 "dendritic cells: 922.9;granulocytes: 2346.7;monocytes: 1364.4" "Cell line enhanced" "Detected in many" "ASC diff: 153.7;Hep G2: 144.0;OE19: 165.4;THP-1: 196.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012122, HPA015130" Enhanced NA NA 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA012122: AB_1848474, HPA015130: AB_1848475" "unprognostic (2.19e-3)" "unprognostic (2.05e-2)" "unprognostic (1.89e-1)" "unprognostic (1.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.26e-1)" "unprognostic (8.58e-2)" "unprognostic (3.87e-3)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (2.00e-3)" "unprognostic (3.64e-1)" "unprognostic (3.67e-3)" "unprognostic (3.40e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (2.18e-3)" 263.1 127.7 67.7 99.6 73.3 147.3 198.8 68.0 102.5 217.2 111.1 209.6 304.4 143.1 48.8 60.2 155.5 144.6 123.0 66.3 75.1 177.6 401.6 177.5 143.3 74.0 69.5 193.2 129.4 114.5 79.8 137.5 74.3 104.6 149.3 4.8 106.2 94.7 64.4 112.3 299.3 91.6 73.6 318.9 126.6 28.3 78.8 62.9 111.9 77.8 39.1 136.7 132.0 78.2 0.4 37.1 4.3 123.7 153.7 78.2 6.0 32.1 73.4 20.9 22.9 50.5 22.5 0.2 59.4 45.9 10.8 8.5 1.2 1.1 11.7 0.3 45.5 74.2 0.6 144.0 95.8 1.1 14.2 95.1 1.9 17.5 0.2 86.5 81.3 48.0 12.2 10.9 53.7 0.8 0.6 14.3 2.1 165.4 22.0 2.6 35.3 3.7 96.0 9.3 2.6 23.1 5.6 0.2 4.5 18.3 26.5 196.1 28.1 52.8 11.8 0.9 1.3 2.4 13.5 9.8 10.8 70.2 7.9 566.8 1364.4 1011.5 24.7 904.8 29.8 58.0 39.8 39.7 922.9 62.5 89.4 51.0 2346.7 28.6 630.2 536.4 28.2 1276.9 67.7 73.3 68.0 102.5 66.3 75.1 74.0 69.5 74.3 73.6 78.8 78.2 479.6 67.3 89.3 21.2 44.2 126.1 130.4 130.7 52.9 0.7 125.5 151.3 30.7 158.7 79.9 73.5 4.2 12.7 83.8 652.3 60.7 86.3 6.5 29.1 89.6 259.2 158.1 55.8 0.2 61.6 24.9 269.9 108.6 24.8 70.5 181.2 587.6 343.9 1362.6 0.0 0.2 349.0 57.0 877.7 438.1 21.8 362.2 608.6 186.7 24.4 190.6 13.4 11.3 10.1 0.2 90.6 883.9 183.6 63.2 87.9 1787.7 329.5 53.4 5.2 216.9 149.2 105.6 21.1 17.6 27.7 107.1 20.7 32.4 129.9 565.1 115.4 FCMR "FAIM3, TOSO" ENSG00000162894 "Fc fragment of IgM receptor" O60667 1 206903317-206923247 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 65.5;lymphoid tissue: 180.6" "Cell type enhanced" "Detected in many" "B-cells: 262.3;dendritic cells: 43.5;NK-cells: 108.1;T-cells: 74.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "RPMI-8226: 171.4;U-266/70: 73.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003910 Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Secreted to blood" NA NA 5500000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA003910: AB_1078798" "prognostic favorable (4.23e-4)" "unprognostic (1.16e-3)" "unprognostic (7.48e-2)" "unprognostic (3.06e-3)" "unprognostic (2.04e-1)" "unprognostic (2.69e-3)" "unprognostic (1.15e-1)" "unprognostic (4.85e-3)" "unprognostic (1.03e-1)" "unprognostic (3.97e-1)" "unprognostic (3.23e-2)" "unprognostic (2.01e-1)" "unprognostic (8.15e-3)" "unprognostic (8.06e-2)" "unprognostic (2.12e-2)" "unprognostic (3.74e-2)" "unprognostic (5.05e-3)" 4.9 1.5 0.3 74.8 0.3 12.6 2.4 0.3 0.8 1.5 0.4 8.0 6.1 2.4 2.6 3.0 1.9 11.3 2.6 0.1 0.4 2.3 5.9 6.0 152.1 0.4 0.1 0.8 1.1 0.5 1.0 1.8 0.2 3.4 9.9 0.2 3.5 1.2 3.6 0.4 65.5 2.3 0.0 115.0 14.2 0.5 0.5 77.2 3.3 1.4 180.6 19.1 1.6 0.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 3.4 0.3 0.3 0.0 0.0 11.6 0.0 0.4 0.7 0.3 0.0 0.6 0.5 0.0 0.2 0.2 0.9 0.0 1.6 0.1 0.0 0.1 0.7 0.3 1.2 0.0 0.0 7.0 0.2 23.5 0.0 0.2 3.5 0.3 0.1 0.0 0.2 4.9 0.6 171.4 0.1 0.3 0.1 0.0 2.8 0.6 13.0 0.0 0.3 0.0 0.5 0.0 0.5 0.2 0.1 73.8 5.9 23.2 0.8 0.1 0.6 7.9 2.8 3.6 209.3 4.3 276.9 882.3 280.1 266.3 3.2 1057.5 483.2 336.0 56.0 218.8 4.3 13.7 687.7 416.6 0.3 0.3 0.3 0.8 0.1 0.4 0.4 0.1 0.2 0.0 0.5 0.6 1.3 0.0 3.9 0.0 262.3 0.0 4.9 0.0 1.2 0.0 3.5 3.0 3.6 5.7 1.3 0.0 0.0 0.1 43.5 0.9 0.0 1.7 0.2 0.8 0.7 1.7 0.0 8.4 0.0 2.9 0.1 3.4 4.1 0.9 0.0 0.6 4.6 1.4 4.4 0.0 0.0 0.6 0.0 5.7 0.0 0.4 0.3 8.1 0.0 0.0 3.6 0.0 108.1 0.0 0.0 1.2 0.3 0.0 30.5 2.9 0.1 1.0 0.7 0.0 0.0 0.2 2.9 0.1 2.3 1.7 0.0 0.0 74.9 0.0 1.9 6.8 FCN1 FCNM ENSG00000085265 "Ficolin 1" O00602 9 134903232-134917912 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 158.9;lung: 46.2;lymphoid tissue: 96.3" "Group enriched" "Detected in many" 10 "Kupffer cells: 504.4;Macrophages: 542.4;monocytes: 1017.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "classical monocyte: 1699.8;intermediate monocyte: 1195.1" "Lineage enhanced" "Detected in all" "monocytes: 1699.8" "Group enriched" "Detected in some" 5 "NB-4: 4.7;U-937: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000685, HPA001295, CAB016760" Enhanced "Secreted to blood" NA NA 1060000000 36000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "CAB016760: , HPA000685: AB_1078840, HPA001295: AB_1078842" "unprognostic (1.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.14e-3)" "unprognostic (1.34e-1)" "unprognostic (9.91e-2)" "unprognostic (1.62e-3)" "unprognostic (3.66e-3)" "unprognostic (2.21e-1)" "unprognostic (1.14e-1)" "unprognostic (5.59e-2)" "unprognostic (2.49e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.73e-2)" "unprognostic (5.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.28e-1)" 15.9 1.4 0.6 47.7 0.5 158.9 5.1 0.8 0.7 2.0 0.5 3.2 0.5 1.5 0.0 1.6 6.4 3.9 5.1 0.5 0.3 4.1 7.2 46.2 3.2 0.5 0.5 1.0 2.5 0.1 1.0 2.4 0.6 2.3 1.6 0.1 2.8 0.5 1.6 1.2 2.8 12.1 0.2 96.3 3.7 0.7 0.7 2.4 2.2 1.1 1.3 10.1 2.3 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.1 0.0 0.1 0.0 7.2 0.1 9.3 1699.8 18.0 2.9 1195.1 3.5 5.9 1.4 1.6 492.6 1.5 1.7 1.6 277.1 2.8 582.2 13.0 2.1 1796.8 0.6 0.5 0.8 0.7 0.5 0.3 0.5 0.5 0.6 0.2 0.7 0.5 2.1 6.4 17.1 0.0 6.6 1.9 0.2 0.0 0.0 0.0 0.3 0.0 2.6 1.5 5.0 1.8 0.0 0.8 6.0 0.1 0.0 0.0 0.1 0.2 0.2 2.7 0.0 5.2 0.0 0.0 1.5 3.6 1.5 0.1 12.6 0.1 3.9 2.6 68.4 0.0 0.0 0.0 0.0 504.4 68.3 0.0 0.0 542.4 0.0 0.0 1017.8 0.0 27.8 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 2.1 0.7 0.0 0.0 1.0 0.5 0.0 0.1 0.2 0.4 1.1 6.1 0.3 0.0 0.2 FCN2 "EBP-37, FCNL, ficolin-2, P35" ENSG00000160339 "Ficolin 2" Q15485 9 134880810-134887523 "Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 99.7" "Cell type enriched" "Detected in some" 18 "Hepatic stellate cells: 1192.6" "Group enriched" "Detected in some" 8 "breast cancer: 1.0;liver cancer: 2.0;prostate cancer: 1.1;renal cancer: 0.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.5;intermediate monocyte: 4.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in some" 23 "spinal cord: 38.6" "Secreted to blood" NA NA 8100000000 1400000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.91e-1)" "unprognostic (1.07e-1)" "unprognostic (6.96e-4)" "unprognostic (3.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.81e-1)" "unprognostic (2.82e-1)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" "unprognostic (1.05e-1)" "unprognostic (3.07e-1)" 4.7 24.6 0.4 0.0 0.4 0.1 7.6 0.3 0.5 0.3 0.5 0.0 0.1 0.1 0.2 0.1 0.3 0.1 0.3 0.6 0.4 6.4 99.7 0.1 0.1 0.3 0.5 0.5 0.5 0.2 3.1 0.0 0.4 3.2 0.0 0.0 3.2 0.4 0.1 0.2 0.1 0.0 0.2 3.1 0.2 0.2 0.4 0.0 2.1 0.1 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.5 0.0 0.0 4.6 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 1.1 0.0 2.2 0.0 0.0 9.0 0.4 0.4 0.3 0.5 0.6 0.4 0.3 0.5 0.4 0.2 0.4 0.3 0.1 0.0 0.0 0.7 3.8 0.0 0.1 0.0 0.0 0.0 3.8 0.4 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 34.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1192.6 12.6 0.0 0.0 0.1 0.0 0.0 64.1 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 FCN3 "FCNH, HAKA1" ENSG00000142748 "Ficolin 3" O75636 1 27369110-27374824 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "liver: 278.3;lung: 724.6" "Cell type enriched" "Detected in some" 16 "Hepatic stellate cells: 2828.6" "Cancer enhanced" "Detected in many" "renal cancer: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025945 Approved "Secreted to blood" NA NA 22800000000 14000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB025945: " "unprognostic (1.59e-1)" "unprognostic (5.25e-2)" "unprognostic (1.55e-2)" "unprognostic (8.27e-2)" "unprognostic (1.45e-3)" "unprognostic (1.27e-2)" "unprognostic (1.87e-3)" "unprognostic (1.21e-1)" "unprognostic (6.28e-4)" "unprognostic (7.07e-2)" "unprognostic (2.86e-2)" "unprognostic (3.23e-2)" "unprognostic (3.87e-3)" "unprognostic (4.14e-2)" "unprognostic (1.02e-1)" "unprognostic (6.97e-2)" "unprognostic (1.61e-2)" 62.6 35.9 1.1 5.7 1.0 0.0 40.8 1.1 1.6 2.7 10.0 4.1 0.8 3.9 0.1 2.8 3.0 1.6 62.1 1.4 1.1 55.2 278.3 724.6 4.3 1.2 1.2 2.4 12.5 2.7 6.6 22.6 1.2 5.3 0.5 0.0 2.5 0.5 9.0 1.9 6.7 1.8 1.2 11.3 8.4 2.4 1.2 0.4 20.4 7.5 0.3 3.0 1.9 1.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 1.1 1.6 1.4 1.1 1.2 1.2 1.2 1.2 1.2 1.0 94.1 0.0 9.3 0.0 16.6 0.8 0.6 0.5 0.6 0.0 0.8 2.8 2.4 52.9 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.5 0.4 0.2 155.1 0.0 136.4 0.1 0.0 0.0 3.8 0.5 0.2 3.8 0.0 2828.6 31.8 0.3 0.0 0.1 0.0 2.0 168.6 0.3 2.7 3.4 2.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.6 0.0 0.1 5.1 0.0 0.0 1.0 2.7 0.5 0.5 1.0 1.1 0.0 4.9 0.5 0.0 0.3 FCRL1 "CD307a, FCRH1, IFGP1, IRTA5" ENSG00000163534 "Fc receptor like 1" Q96LA6 1 157794403-157820120 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "bone marrow: 8.0;intestine: 8.6;lymphoid tissue: 27.3" "Cell type enriched" "Detected in some" 26 "B-cells: 88.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 39.3;naive B-cell: 68.1" "Lineage enriched" "Detected in many" 62 "B-cells: 68.1" "Group enriched" "Detected in some" 26 "Daudi: 5.4;U-698: 17.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013323 Enhanced NA NA 290000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA013323: AB_1848480" "unprognostic (6.52e-4)" "unprognostic (3.49e-3)" "unprognostic (8.68e-3)" "unprognostic (8.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.01e-5)" "unprognostic (1.47e-2)" "unprognostic (5.48e-3)" "unprognostic (1.40e-2)" "unprognostic (4.30e-2)" "unprognostic (1.81e-1)" "unprognostic (2.85e-2)" "unprognostic (1.44e-3)" "unprognostic (1.96e-1)" "unprognostic (1.65e-2)" "unprognostic (4.80e-2)" "unprognostic (6.74e-2)" 0.2 0.0 0.0 10.1 0.0 8.0 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 0.2 0.2 0.6 27.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.5 0.0 0.6 0.0 0.0 0.0 8.6 0.0 0.0 17.8 0.8 0.0 0.0 3.0 0.4 0.0 22.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 39.3 0.0 0.0 0.0 68.1 0.0 0.1 1.1 0.2 0.5 0.0 0.3 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.7 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.5 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 FCRL3 "CD307c, FCRH3, IFGP3, IRTA3, SPAP2, SPAP2a, SPAP2b, SPAP2c, SPAP2d, SPAP2e" ENSG00000160856 "Fc receptor like 3" Q96P31 1 157674321-157700769 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 49.5" "Cell type enhanced" "Detected in some" "B-cells: 54.3;dendritic cells: 21.2;Early spermatids: 8.0;Late spermatids: 9.1;NK-cells: 30.9;T-cells: 12.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive B-cell: 35.3" "Group enriched" "Detected in many" 54 "B-cells: 35.3;NK-cells: 20.4;T-cells: 19.0" "Cell line enriched" "Detected in some" 7 "Daudi: 9.9" "Low region specificity" "Detected in some" HPA048022 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA048022: AB_2732541" "unprognostic (6.73e-3)" "unprognostic (5.06e-4)" "unprognostic (1.13e-2)" "unprognostic (2.08e-4)" "unprognostic (3.86e-1)" "unprognostic (1.74e-5)" "unprognostic (1.09e-2)" "unprognostic (4.29e-3)" "unprognostic (3.69e-3)" "unprognostic (2.46e-4)" "unprognostic (1.13e-1)" "unprognostic (2.55e-2)" "unprognostic (2.01e-4)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (2.21e-1)" "unprognostic (6.69e-2)" 0.4 0.0 0.0 14.1 0.0 1.1 0.1 0.0 0.0 0.1 0.0 1.1 0.3 0.2 0.1 0.1 0.1 1.0 0.2 0.0 0.0 0.2 0.8 0.9 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.2 0.0 0.8 0.0 0.1 0.0 8.7 0.1 0.0 27.5 1.5 0.2 0.0 4.6 0.4 0.1 36.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 19.0 0.0 1.8 30.3 2.6 13.2 0.0 35.3 0.2 8.3 0.4 20.4 0.0 0.0 11.3 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 54.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 8.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.1 0.0 0.0 1.2 0.0 9.1 0.0 0.4 0.0 1.0 0.9 0.0 30.9 0.5 0.0 0.0 1.1 0.0 3.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 12.4 0.0 0.0 0.0 FCRL5 "BXMAS1, CD307e, FCRH5, IRTA2" ENSG00000143297 "Fc receptor like 5" Q96RD9 1 157513377-157552515 "CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 36.3" "Group enriched" "Detected in some" 5 "B-cells: 102.6;Early spermatids: 63.6;Plasma cells: 190.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "memory B-cell: 13.0;naive B-cell: 14.2" "Lineage enriched" "Detected in single" 17 "B-cells: 14.2" "Group enriched" "Detected in some" 5 "U-266/70: 3.4;U-698: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 169000000 65000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.30e-3)" "unprognostic (3.51e-2)" "unprognostic (7.59e-3)" "unprognostic (1.57e-2)" "unprognostic (9.41e-3)" "unprognostic (4.32e-5)" "unprognostic (2.61e-2)" "unprognostic (6.93e-2)" "unprognostic (7.40e-2)" "unprognostic (7.66e-3)" "unprognostic (4.01e-1)" "unprognostic (1.39e-1)" "unprognostic (9.51e-10)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.99e-2)" "unprognostic (2.78e-1)" 0.4 0.4 0.0 13.8 0.0 2.3 2.4 0.0 0.1 0.6 0.0 5.5 5.8 0.1 0.3 0.8 0.4 1.2 0.3 0.0 0.0 0.4 0.3 1.1 24.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 4.4 0.0 3.8 0.3 0.0 0.0 5.0 0.1 0.1 15.1 4.5 0.6 0.0 4.1 0.6 0.0 36.3 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 102.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 3.1 2.9 0.1 0.0 0.0 63.6 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.3 1.1 0.0 1.3 0.0 0.4 1.8 0.3 0.0 0.1 0.0 0.0 0.3 0.3 10.1 0.3 0.2 23.2 0.0 0.5 0.0 0.0 0.5 0.2 0.0 0.0 0.0 190.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.3 1.2 0.1 0.1 0.0 0.7 5.7 0.0 0.6 0.0 FCRL6 "FcRH6, FLJ16056, IFGP6" ENSG00000181036 "Fc receptor like 6" Q6DN72 1 159800511-159816257 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;lymphoid tissue: 12.8" "Cell type enhanced" "Detected in some" "dendritic cells: 60.6;NK-cells: 150.4;T-cells: 31.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 142.9;memory CD8 T-cell: 134.3;naive CD8 T-cell: 102.8;NK-cell: 51.3" "Group enriched" "Detected in many" 26 "NK-cells: 51.3;T-cells: 142.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.64e-3)" "unprognostic (1.30e-2)" "unprognostic (1.97e-2)" "unprognostic (1.62e-3)" "unprognostic (1.85e-1)" "unprognostic (1.84e-3)" "unprognostic (5.79e-3)" "unprognostic (6.65e-3)" "unprognostic (2.76e-2)" "unprognostic (3.91e-1)" "unprognostic (1.98e-1)" "unprognostic (1.61e-1)" "unprognostic (1.52e-5)" "unprognostic (3.98e-1)" "unprognostic (1.13e-1)" "unprognostic (8.78e-2)" "unprognostic (9.18e-2)" 0.8 1.5 0.3 1.9 0.4 7.9 1.1 0.7 0.4 0.6 0.3 0.7 1.0 1.3 2.3 0.6 1.0 2.2 0.8 0.4 0.5 0.6 3.3 5.7 5.8 0.9 0.5 1.4 0.3 0.3 0.3 0.5 0.6 0.7 0.5 0.0 2.3 0.4 0.5 0.3 1.4 0.9 0.5 12.8 0.8 0.4 0.6 1.3 0.6 0.1 1.9 1.2 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.2 0.1 142.9 0.3 3.0 0.1 25.5 134.3 3.7 0.1 10.9 102.8 1.5 51.3 1.4 0.2 0.1 53.6 0.3 0.4 0.7 0.4 0.4 0.5 0.9 0.5 0.6 0.5 0.6 0.9 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.7 0.0 0.0 0.0 60.6 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 2.7 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.0 1.0 1.1 0.0 150.4 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.0 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.0 FCRLA "FCRL, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FCRLM1, FCRLX, FREB, MGC4595" ENSG00000132185 "Fc receptor like A" Q7L513 1 161706972-161714352 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 98.4" "Group enriched" "Detected in some" 6 "B-cells: 124.2;Melanocytes: 67.6" "Cancer enriched" "Detected in many" 21 "melanoma: 38.8" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 9 "memory B-cell: 368.0;naive B-cell: 341.5" "Lineage enriched" "Detected in many" 10 "B-cells: 368.0" "Group enriched" "Detected in some" 6 "Daudi: 484.1;SK-MEL-30: 197.8;U-698: 260.5" "Not detected" "Not detected" "Not detected" "Not detected" CAB016545 Enhanced "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB016545: AB_2247037" "unprognostic (5.46e-4)" "unprognostic (7.19e-2)" "unprognostic (3.69e-3)" "unprognostic (4.75e-4)" "unprognostic (4.69e-2)" "unprognostic (1.48e-4)" "unprognostic (1.45e-2)" "unprognostic (4.15e-3)" "unprognostic (8.66e-2)" "unprognostic (3.58e-4)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (6.84e-5)" "unprognostic (3.21e-2)" "unprognostic (1.55e-1)" "unprognostic (1.56e-1)" "unprognostic (2.08e-2)" 0.8 0.2 0.5 23.5 0.3 4.1 0.5 1.1 0.7 0.3 0.3 2.6 0.9 0.4 0.6 0.5 0.1 1.1 0.6 0.4 0.2 0.3 0.4 0.6 68.5 0.3 0.3 0.2 0.0 0.0 0.0 0.3 0.3 0.8 2.8 0.3 2.3 0.1 0.3 1.2 19.1 0.4 0.1 38.5 4.1 0.2 0.5 7.7 0.5 0.3 98.4 3.4 0.1 0.4 0.7 0.0 0.0 0.0 0.4 0.4 0.0 2.7 7.4 0.2 0.5 0.0 0.0 484.1 0.2 7.0 0.0 0.1 0.0 0.7 0.8 1.8 0.0 0.5 0.0 0.0 0.0 0.2 2.0 0.4 0.5 2.4 0.4 0.1 0.0 0.0 0.9 26.7 0.1 0.0 0.1 0.3 0.1 0.0 0.1 4.0 8.3 52.4 0.0 0.1 0.0 0.0 0.3 0.1 197.8 0.0 0.0 0.2 0.5 0.6 0.7 0.5 0.5 0.7 0.3 260.5 2.9 0.3 44.3 0.4 0.3 0.2 0.8 0.0 0.1 368.0 0.2 0.4 0.4 341.5 0.2 0.1 0.6 0.2 0.2 38.4 0.2 17.0 0.5 0.3 1.1 0.7 0.4 0.2 0.3 0.3 0.3 0.1 0.5 0.4 0.0 0.0 0.6 0.0 124.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.7 67.6 0.0 0.4 0.0 1.0 0.5 0.1 0.3 0.1 0.0 14.3 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.4 0.0 1.6 0.0 0.1 0.0 FCRLB "FCRL2, FCRLM2, FCRLY, FLJ31052, FREB-2" ENSG00000162746 "Fc receptor like B" Q6BAA4 1 161721563-161728143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 7.5;NK-cells: 11.3;Proximal tubular cells: 14.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 7.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.8;Daudi: 6.0;fHDF/TERT166: 8.8;HMC-1: 7.4;PC-3: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" CAB026139 Uncertain Supported Cytosol "Intracellular and membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB026139: " "unprognostic (1.87e-1)" "unprognostic (1.20e-4)" "unprognostic (5.77e-3)" "unprognostic (7.49e-3)" "unprognostic (1.73e-3)" "unprognostic (2.95e-1)" "unprognostic (2.98e-2)" "unprognostic (1.18e-3)" "unprognostic (1.89e-1)" "unprognostic (3.59e-2)" "unprognostic (1.39e-1)" "unprognostic (1.60e-1)" "unprognostic (1.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.27e-1)" "unprognostic (9.92e-3)" "unprognostic (3.14e-2)" 0.2 0.1 0.5 0.7 0.4 0.0 0.1 0.5 0.7 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.4 0.7 0.3 0.1 0.9 0.5 0.5 0.1 0.2 0.1 0.0 0.1 0.6 0.1 0.1 0.1 0.3 0.9 0.0 0.2 0.1 0.0 0.4 0.3 0.1 0.1 0.4 0.0 0.1 0.0 1.8 0.2 0.1 0.6 0.6 0.1 0.0 0.3 0.4 0.6 0.0 3.7 4.8 1.2 1.2 0.1 0.1 6.0 0.2 8.8 0.2 0.0 0.2 0.3 3.1 0.1 0.3 0.2 0.1 0.1 0.2 0.0 7.4 1.1 0.0 2.1 0.1 0.3 1.1 0.0 0.3 0.3 0.1 0.3 0.0 2.1 0.1 0.0 4.4 0.0 0.4 0.2 0.1 0.2 0.0 0.0 0.0 0.1 1.9 0.2 0.0 0.0 0.6 1.3 0.6 1.3 0.7 0.0 0.0 2.3 2.5 0.4 0.6 6.4 0.1 1.8 1.8 0.0 0.6 3.4 1.1 1.0 0.4 4.7 0.5 0.8 1.0 3.7 0.2 0.0 0.0 0.5 0.5 0.4 0.5 0.7 0.5 0.4 0.5 0.5 0.6 0.4 0.4 0.6 2.8 0.0 0.0 0.3 2.9 1.1 1.1 1.0 0.6 0.2 1.5 1.5 1.5 0.0 1.2 3.7 0.0 2.1 3.9 0.1 5.9 1.3 0.1 0.3 1.3 2.3 1.2 5.3 0.9 1.1 5.6 1.1 0.0 0.4 0.0 1.2 7.5 1.2 1.4 0.0 1.2 0.0 0.0 1.9 1.2 0.2 0.0 3.4 1.8 0.0 0.7 3.4 11.3 0.0 0.3 1.0 0.1 0.4 3.0 0.6 0.0 14.7 0.7 0.7 0.0 0.2 1.6 2.7 1.4 1.3 0.4 0.8 2.4 2.2 0.0 1.1 FDCSP "C4orf7, FDC-SP" ENSG00000181617 "Follicular dendritic cell secreted protein" Q8NFU4 4 70226124-70235252 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "lymphoid tissue: 3257.5;salivary gland: 6608.7" "Group enriched" "Detected in some" 25 "Breast glandular cells: 90.8;Breast myoepithelial cells: 87.9;Ductal cells: 75.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 336.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.6;GAMG: 7.5;HL-60: 1.5;K-562: 1.4;RH-30: 2.1;U-87 MG: 5.4" "Not detected" "Not detected" "HPA014326, CAB014890" Enhanced "Secreted in other tissues" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 35: Glandular cells - Unknown function" "CAB014890: , HPA014326: AB_1845719" "unprognostic (1.26e-3)" "unprognostic (2.32e-1)" "unprognostic (8.73e-3)" "unprognostic (9.62e-2)" "prognostic favorable (2.38e-4)" "unprognostic (5.99e-3)" "prognostic favorable (1.32e-4)" "unprognostic (2.04e-1)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.79e-1)" "unprognostic (1.96e-1)" "unprognostic (3.68e-2)" "unprognostic (2.80e-1)" "unprognostic (7.83e-2)" 4.8 1.8 0.0 313.8 0.0 0.0 183.5 0.0 0.0 0.2 0.2 24.6 1.8 4.8 0.1 13.4 0.9 2.7 1.6 0.0 0.1 0.3 1.9 1.4 1052.7 0.1 0.6 0.5 2.7 0.0 0.5 0.7 0.0 1.6 18.3 0.0 6608.7 0.1 1.4 0.5 49.5 4.2 0.0 33.2 10.1 0.3 0.3 17.2 3.3 0.0 3257.5 11.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.1 5.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 90.8 87.9 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 75.6 0.0 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 FDXACB1 "hCG_2033039, LOC91893" ENSG00000255561 "Ferredoxin-fold anticodon binding domain containing 1" Q9BRP7 11 111874056-111881243 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 37.1;Late spermatids: 14.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039012, HPA061375" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA039012: AB_10670916, HPA061375: " "unprognostic (2.91e-2)" "unprognostic (3.32e-3)" "unprognostic (1.32e-2)" "unprognostic (6.81e-7)" "unprognostic (1.32e-1)" "unprognostic (9.64e-2)" "unprognostic (2.05e-1)" "unprognostic (7.11e-3)" "unprognostic (3.95e-2)" "unprognostic (7.42e-2)" "unprognostic (3.67e-1)" "unprognostic (1.04e-1)" "unprognostic (1.09e-2)" "unprognostic (6.57e-2)" "unprognostic (4.42e-1)" "unprognostic (4.61e-2)" "unprognostic (1.79e-2)" 1.1 1.9 0.9 1.9 1.0 2.0 2.1 0.8 1.2 1.7 0.7 1.4 1.6 1.4 2.4 1.1 1.5 1.0 0.9 1.0 1.2 1.5 1.6 1.7 3.1 1.0 1.0 1.5 1.5 1.6 0.9 1.2 0.9 1.2 1.7 0.7 0.8 0.9 0.7 2.7 1.5 1.1 1.0 2.4 1.0 3.1 1.2 1.7 1.3 0.8 3.2 1.6 0.8 1.1 1.4 1.9 2.1 5.3 2.0 1.8 1.2 1.1 1.2 1.2 1.2 2.4 3.1 5.5 2.7 1.0 1.5 4.3 2.6 2.5 2.7 6.9 1.1 6.1 1.1 1.8 1.2 6.4 5.3 1.5 1.5 1.7 2.2 1.0 2.2 6.5 4.4 6.4 2.3 1.8 6.0 6.2 1.4 6.0 2.7 3.6 1.6 6.5 2.8 2.5 1.0 1.6 1.5 3.2 1.4 1.2 4.5 3.9 1.7 2.5 2.7 3.0 2.6 3.6 5.5 14.1 1.6 9.1 3.7 0.3 2.3 1.5 5.0 3.7 6.5 4.6 4.4 4.4 3.8 3.8 6.5 7.5 0.7 4.8 3.0 3.6 2.5 3.7 0.9 1.0 0.8 1.2 1.0 1.2 1.0 1.0 0.9 1.0 1.2 1.1 2.2 6.4 0.6 0.7 3.1 0.8 1.3 4.2 1.2 3.0 1.6 1.4 1.6 0.0 3.0 0.0 0.0 3.4 1.3 1.2 5.9 2.5 37.1 1.5 1.2 1.8 2.4 0.8 1.0 3.3 1.9 1.3 1.1 0.9 1.3 2.2 2.2 1.8 4.0 1.7 1.3 1.4 4.1 1.3 1.2 14.2 3.1 2.0 0.0 1.9 2.2 3.2 4.1 1.0 1.2 2.1 0.5 0.4 1.6 1.9 0.9 2.3 1.6 2.5 6.6 1.1 1.2 7.5 9.1 1.0 1.3 2.2 2.6 3.8 1.6 0.8 FETUB ENSG00000090512 "Fetuin B" Q9UGM5 3 186635969-186653141 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 234.6" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 47.2" "Cancer enriched" "Detected in some" 12 "liver cancer: 44.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035132, HPA035133" Supported Approved Vesicles "Secreted to blood" NA NA 47500000000 3600000000 "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA035132: AB_10601650, HPA035133: " "unprognostic (9.01e-2)" "unprognostic (1.95e-1)" "unprognostic (4.62e-1)" "unprognostic (8.74e-2)" "unprognostic (6.28e-3)" "unprognostic (1.24e-2)" "unprognostic (7.55e-2)" "unprognostic (9.78e-2)" "unprognostic (1.73e-2)" "unprognostic (9.18e-2)" "unprognostic (1.79e-1)" "unprognostic (8.39e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.6 0.0 0.1 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.1 0.0 0.4 234.6 0.0 0.0 0.1 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 5.8 0.0 2.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 3.9 0.0 5.3 0.2 0.2 0.1 0.0 2.7 0.2 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.7 47.2 0.0 0.0 0.0 0.2 0.0 2.9 0.0 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 FGA ENSG00000171560 "Fibrinogen alpha chain" P02671 4 154583128-154590745 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 388 "liver: 18396.9" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 17365.8" "Cancer enriched" "Detected in many" 43 "liver cancer: 2431.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 429.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016776, HPA051370, HPA064755" Supported Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 407000000 140000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB016776: , HPA051370: AB_2681458, HPA064755: AB_2685345" "unprognostic (5.95e-2)" "unprognostic (6.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.29e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.23e-6)" "unprognostic (4.20e-1)" "unprognostic (1.41e-1)" 2.1 1.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.5 0.0 0.6 0.6 0.7 0.9 13.2 1.2 0.0 0.0 18.8 18396.9 5.3 0.1 0.0 0.0 0.7 18.8 0.0 0.5 0.9 0.0 0.4 0.0 0.0 0.5 0.0 0.5 0.6 0.9 0.0 0.0 9.9 47.4 3.7 0.0 0.1 0.4 0.0 0.1 0.6 0.7 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 0.0 2.7 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.4 0.1 429.3 0.0 6.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.5 6.1 0.0 0.0 0.5 0.2 0.1 3.5 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 1.0 0.0 1.9 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 414.6 3.2 0.0 0.0 0.0 0.0 0.0 1.9 38.6 28.3 0.1 0.2 8.1 0.0 205.9 0.0 1.8 0.1 0.1 1.1 1.3 0.0 0.0 238.8 17365.8 0.1 0.0 0.0 0.0 0.0 328.3 0.0 46.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 1.2 0.0 0.0 0.0 2.3 9.5 0.0 0.0 0.0 0.1 17.4 0.7 0.0 0.0 0.1 17.6 0.0 0.0 0.0 FGB ENSG00000171564 "Fibrinogen beta chain" P02675 4 154563011-154572807 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 373 "liver: 17944.9" "Cell type enriched" "Detected in some" 40 "Hepatocytes: 17273.6" "Cancer enriched" "Detected in many" 42 "liver cancer: 2262.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "Hep G2: 249.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001900, HPA001901, CAB008624" Enhanced Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 110000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB008624: AB_1615610, HPA001900: AB_1078865, HPA001901: AB_1078864" "unprognostic (1.16e-1)" "unprognostic (3.89e-2)" "unprognostic (4.65e-2)" "unprognostic (3.44e-1)" "unprognostic (2.20e-3)" "unprognostic (1.42e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.72e-5)" "unprognostic (2.48e-2)" "unprognostic (7.91e-2)" 2.0 0.8 0.0 0.0 0.0 0.1 2.8 0.0 0.0 1.3 0.0 0.5 0.0 0.6 0.3 0.6 0.8 0.4 1.4 0.0 0.0 48.0 17944.9 0.5 0.1 0.0 0.0 0.6 3.3 0.0 0.5 1.0 0.0 0.4 0.0 0.0 0.4 0.0 0.5 0.5 1.2 0.0 0.0 12.1 6.8 0.5 0.0 0.3 0.4 0.0 0.1 0.5 0.7 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 2.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.2 0.1 249.9 0.0 5.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.8 0.0 0.9 0.0 2.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 39.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.6 251.6 0.0 3.7 0.0 0.0 0.0 0.0 1.9 10.6 0.5 0.6 0.8 13.1 1.8 302.1 0.0 3.8 0.2 0.0 0.0 5.9 0.0 0.0 318.1 17273.6 0.3 0.0 0.0 0.0 0.0 421.7 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.7 0.0 0.0 0.0 FGF10 ENSG00000070193 "Fibroblast growth factor 10" O15520 5 44300247-44389706 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Disease variant, Ectodermal dysplasia, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 21.6;Fibroblasts: 14.6;Leydig cells: 8.4;Muller glia cells: 4.3;Peritubular cells: 10.5" "Cancer enriched" "Detected in some" 6 "breast cancer: 5.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "AF22: 27.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB010315 Uncertain "Secreted in other tissues" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "CAB010315: AB_2262731" "unprognostic (1.40e-1)" "unprognostic (1.25e-1)" "unprognostic (8.54e-2)" "unprognostic (1.08e-1)" "unprognostic (3.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.54e-2)" "unprognostic (4.06e-3)" "unprognostic (2.72e-2)" "unprognostic (6.73e-2)" "unprognostic (5.59e-2)" "unprognostic (4.55e-2)" "unprognostic (1.24e-2)" "unprognostic (1.11e-2)" "unprognostic (2.14e-2)" "unprognostic (5.23e-4)" 13.9 1.6 0.3 2.6 0.9 0.0 15.2 0.5 0.7 14.6 1.1 7.0 0.4 2.4 4.4 1.4 8.5 2.8 0.7 0.6 0.7 0.7 0.1 2.6 0.6 1.3 1.9 17.3 4.8 0.0 2.1 5.5 1.1 4.6 1.5 0.3 5.4 3.0 0.7 0.9 2.9 1.3 1.6 0.0 4.3 0.8 1.7 1.1 5.3 3.8 0.2 5.0 12.0 0.4 0.0 0.0 27.9 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.5 0.7 0.6 0.7 1.3 1.9 1.1 1.6 1.7 0.4 1.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 21.6 0.9 0.0 0.0 3.0 0.5 0.0 14.6 0.0 0.3 0.0 1.6 0.4 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.5 8.4 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.3 0.3 0.0 10.5 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 FGF17 FGF-13 ENSG00000158815 "Fibroblast growth factor 17" O60258 8 22042398-22048809 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7;choroid plexus: 10.6" "Group enriched" "Detected in some" 4 "Bipolar cells: 9.3;Cone photoreceptor cells: 14.6;Excitatory neurons: 10.6;Inhibitory neurons: 13.1" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.6;testis cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.1;RPMI-8226: 1.8" "Region enriched" "Detected in single" 4 "basal ganglia: 2.1" "Region enhanced" "Detected in single" "cerebellum: 2.1" HPA052600 Uncertain "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA052600: AB_2681881" "unprognostic (3.45e-2)" "unprognostic (1.64e-2)" "unprognostic (3.03e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-2)" "unprognostic (3.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (5.65e-2)" "unprognostic (1.34e-1)" "unprognostic (7.92e-5)" "unprognostic (6.85e-2)" "unprognostic (2.58e-4)" "unprognostic (6.55e-3)" "unprognostic (7.18e-2)" "unprognostic (2.41e-1)" "unprognostic (1.95e-3)" 0.5 3.9 15.1 0.0 14.9 0.1 0.4 22.0 25.7 3.0 10.6 0.4 0.0 1.1 0.1 0.2 1.5 0.2 0.5 14.3 14.2 1.4 0.4 0.7 0.0 11.9 12.2 1.5 1.2 0.8 5.1 0.1 12.2 2.7 0.0 1.1 0.7 0.1 0.0 0.5 0.4 0.3 10.9 3.6 0.5 0.7 14.2 0.4 4.8 0.0 0.0 0.6 1.3 14.4 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.8 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.9 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 14.9 22.0 25.7 14.3 14.2 11.9 12.2 12.2 10.9 14.2 14.4 0.2 0.0 0.0 2.3 0.0 0.0 0.3 0.1 0.0 9.3 0.2 0.4 1.1 0.0 0.2 0.0 14.6 0.1 0.0 0.1 0.0 0.1 1.8 0.0 0.1 0.1 0.0 0.0 10.6 0.2 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.1 1.7 13.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 1.8 1.0 0.0 0.6 0.0 2.0 2.4 0.1 0.0 1.2 0.1 0.2 0.0 0.0 0.2 1.3 0.0 0.3 0.2 0.2 0.5 0.0 0.0 0.3 0.1 0.4 0.0 0.1 FGF18 "FGF-18, ZFGF5" ENSG00000156427 "Fibroblast growth factor 18" O76093 5 171419647-171457626 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 16.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 19.8;Cardiomyocytes: 24.4;Endometrial ciliated cells: 13.0;Glandular and luminal cells: 24.9" "Group enriched" "Detected in many" 6 "endometrial cancer: 19.0;ovarian cancer: 21.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 55 "EFO-21: 188.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 2.3" HPA018795 Uncertain "Secreted in other tissues" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA018795: AB_1848523" "unprognostic (3.01e-1)" "unprognostic (2.38e-2)" "unprognostic (1.23e-1)" "unprognostic (3.66e-3)" "unprognostic (6.62e-3)" "unprognostic (1.50e-1)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (2.98e-3)" "unprognostic (3.65e-2)" "unprognostic (3.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.37e-8)" "unprognostic (7.33e-2)" "unprognostic (2.58e-1)" "unprognostic (3.19e-1)" "unprognostic (2.76e-2)" 4.2 0.3 1.1 0.3 1.2 0.0 2.1 1.1 2.1 1.0 1.1 0.9 0.6 0.9 0.1 0.3 1.5 0.7 16.1 1.1 1.2 0.7 0.1 2.6 0.3 1.4 1.3 0.4 0.5 0.1 1.6 0.5 1.6 1.2 0.1 0.1 1.1 0.3 3.8 1.6 0.7 0.4 1.1 0.5 0.6 0.8 1.5 0.3 1.9 0.4 0.2 0.8 0.5 1.2 0.0 0.3 0.3 0.9 0.0 0.0 0.3 0.1 0.0 0.0 0.1 3.4 0.4 0.2 188.2 0.0 0.2 0.2 0.0 0.1 0.0 3.1 0.3 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.9 0.1 3.4 0.0 0.1 0.0 0.3 2.1 0.1 0.2 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 1.5 0.1 0.5 0.0 0.2 0.6 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 1.1 2.1 1.1 1.2 1.4 1.3 1.6 1.1 1.5 1.2 6.9 6.4 0.0 0.0 2.0 2.4 2.6 0.5 6.2 0.1 6.6 19.8 24.4 1.5 1.3 1.8 0.0 0.1 3.4 0.5 0.0 0.0 6.2 13.0 3.1 4.2 1.8 0.0 0.8 0.0 0.3 9.4 0.5 24.9 0.0 0.0 2.9 0.0 0.1 0.0 2.1 1.0 0.0 0.0 2.1 0.7 0.3 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.4 0.4 3.2 1.1 0.0 0.0 0.0 0.0 5.4 4.6 0.7 1.6 5.6 3.1 0.0 2.4 0.5 1.8 0.9 FGF19 ENSG00000162344 "Fibroblast growth factor 19" O95750 11 69698238-69704022 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "gallbladder: 237.1" "Group enriched" "Detected in some" 4 "Cholangiocytes: 24.3;Ductal cells: 15.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "CAPAN-2: 138.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA036082 Approved "Secreted to blood" NA NA 133000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "HPA036082: AB_10669665" "unprognostic (7.46e-3)" "unprognostic (2.43e-3)" "unprognostic (5.52e-3)" "unprognostic (1.22e-1)" "unprognostic (4.68e-3)" "unprognostic (6.45e-2)" "unprognostic (5.72e-3)" "unprognostic (2.26e-1)" "unprognostic (6.39e-3)" "unprognostic (1.66e-2)" "unprognostic (8.82e-3)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.4 0.1 0.0 237.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 138.2 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.2 0.0 0.0 0.7 1.4 0.6 24.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.1 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.5 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.0 1.3 0.0 0.0 0.0 0.3 1.8 FGF21 ENSG00000105550 "Fibroblast growth factor 21" Q9NSA1 19 48755524-48758333 "Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 106 "liver: 84.1" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 116.4" "Cancer enriched" "Detected in single" 315 "liver cancer: 33.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HHSteC: 1.4;U-2 OS: 4.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061286 Supported "Secreted to blood" NA NA 254000 73000 "Cluster 62: Liver - Hemostasis" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA061286: AB_2684466" "unprognostic (1.64e-2)" "unprognostic (3.62e-1)" "unprognostic (3.21e-2)" "unprognostic (3.42e-1)" "unprognostic (1.54e-1)" "unprognostic (1.85e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 84.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FGF22 ENSG00000070388 "Fibroblast growth factor 22" Q9HCT0 19 639879-644371 "Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;skin 1: 13.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.4;Horizontal cells: 13.5;Muller glia cells: 4.7;Rod photoreceptor cells: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AN3-CA: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (2.84e-3)" "unprognostic (1.04e-2)" "unprognostic (1.17e-1)" "unprognostic (5.25e-4)" "unprognostic (1.16e-1)" "unprognostic (3.66e-3)" "unprognostic (2.85e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-4)" "unprognostic (1.76e-1)" "unprognostic (1.70e-1)" "unprognostic (3.55e-2)" "unprognostic (2.91e-1)" "unprognostic (1.31e-1)" "unprognostic (8.36e-2)" 0.5 0.3 2.6 0.0 2.8 0.0 0.6 2.4 4.9 0.7 1.3 0.6 0.2 0.6 0.0 0.5 1.0 0.0 0.3 2.5 2.1 0.4 0.2 0.3 0.0 2.6 2.6 2.9 0.2 0.0 0.6 0.0 2.7 1.1 0.0 0.1 0.6 0.1 0.7 13.5 0.4 0.0 1.8 0.2 0.6 1.1 2.9 0.0 0.2 0.0 0.0 0.9 0.9 3.0 0.2 0.3 0.1 1.9 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.8 0.1 0.6 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.7 0.0 0.0 0.3 0.1 0.2 0.4 0.7 0.5 0.0 0.1 0.0 0.3 0.1 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.1 0.1 0.2 0.1 0.0 0.1 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.8 2.4 4.9 2.5 2.1 2.6 2.6 2.7 1.8 2.9 3.0 0.6 3.2 0.0 1.0 0.6 0.8 1.3 0.0 0.0 8.4 0.5 0.6 1.4 1.5 0.1 0.0 0.0 0.4 1.2 0.6 0.0 0.1 0.6 0.6 0.6 0.5 0.0 0.4 1.6 0.0 0.4 1.1 0.0 1.0 0.0 0.5 0.7 0.4 0.2 13.5 0.9 0.5 0.0 0.0 1.0 0.2 0.3 0.1 1.8 0.0 0.2 4.7 0.0 0.0 1.6 0.4 0.1 0.0 0.7 1.5 0.8 0.5 0.2 6.4 0.0 1.9 0.9 1.1 2.0 0.0 1.0 3.4 1.6 0.2 0.5 0.6 FGF23 ENSG00000118972 "Fibroblast growth factor 23" Q9GZV9 12 4368227-4379712 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" Differentiation "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "brain: 126.3;choroid plexus: 104.9" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 10.4;Early spermatids: 6.6;Hepatic stellate cells: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 10.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 10.8" "Cell line enhanced" "Detected in some" "AF22: 1.9;HBEC3-KT: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted to blood" NA NA 56800 "Cluster 42: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (1.31e-1)" "unprognostic (2.18e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-1)" 0.2 0.1 74.8 0.1 73.5 0.5 0.2 73.8 126.3 0.0 104.9 0.2 0.3 0.3 1.2 0.2 0.3 0.1 5.0 74.1 74.1 0.2 4.1 0.2 0.2 73.8 86.6 0.2 0.1 0.1 0.0 0.2 77.8 0.1 0.6 2.3 0.5 0.0 1.2 0.3 0.1 0.3 72.9 0.5 0.2 0.5 73.3 0.1 0.1 0.3 0.6 0.1 0.0 78.6 0.0 0.0 1.9 0.6 0.9 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.7 0.1 0.0 0.3 0.1 0.4 0.2 1.4 0.0 0.0 0.2 0.0 0.3 0.2 0.5 0.4 0.1 0.5 0.0 0.9 1.1 0.1 0.1 0.0 0.1 0.8 0.0 0.0 0.2 0.5 0.5 0.1 0.0 0.3 0.0 0.3 0.2 0.4 0.4 0.3 0.0 0.6 0.1 0.3 0.4 0.3 0.0 0.7 0.1 0.5 0.1 0.0 0.0 0.1 0.4 0.1 0.4 10.8 1.4 2.0 1.6 1.5 1.9 1.8 1.5 1.2 1.2 1.9 1.7 1.7 4.8 2.2 2.5 1.9 1.6 1.1 74.8 73.5 73.8 126.3 74.1 74.1 73.8 86.6 77.8 72.9 73.3 78.6 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.9 1.5 0.0 0.0 10.4 0.1 0.3 0.0 0.0 0.0 6.6 0.0 0.2 0.5 0.0 0.0 0.8 0.0 0.1 0.4 0.0 0.1 0.0 0.0 13.6 0.0 0.2 1.7 0.3 0.0 0.0 0.6 0.3 1.8 0.3 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.3 0.2 0.5 0.3 0.0 0.0 0.0 0.2 0.1 0.1 0.2 FGF3 "HBGF-3, INT2" ENSG00000186895 "Fibroblast growth factor 3" P11487 11 69809968-69819416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "brain: 3.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.4" "Region enriched" "Detected in single" 5 "cerebellum: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 3.1" "Not detected" "Not detected" HPA012692 Enhanced "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA012692: AB_1848526" "unprognostic (6.42e-3)" "unprognostic (7.82e-2)" "unprognostic (1.89e-1)" "unprognostic (3.61e-1)" "unprognostic (7.75e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.1 0.6 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FGF4 "HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF" ENSG00000075388 "Fibroblast growth factor 4" P08620 11 69771022-69775341 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 1.1;Early spermatids: 3.1;Late spermatids: 1.4;Spermatocytes: 1.5" "Cancer enriched" "Detected in some" 5 "testis cancer: 13.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "NTERA-2: 16.1;SuSa: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA011209 Uncertain "Secreted in other tissues" NA NA 326000 "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA011209: AB_1848527" "unprognostic (1.47e-2)" "unprognostic (6.22e-2)" "unprognostic (7.77e-2)" "unprognostic (8.56e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FGF5 ENSG00000138675 "Fibroblast growth factor 5" P12034 4 80266599-80336680 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.7;gallbladder: 3.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Excitatory neurons: 9.4;Microglial cells: 1.9;Proximal tubular cells: 4.1" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 11.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 64.1;BJ hTERT+: 120.0;fHDF/TERT166: 88.0;HBF TERT88: 88.0;LHCN-M2: 81.1;U-138 MG: 109.5;U-251 MG: 55.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB010313, HPA042442" Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010313: AB_2102677, HPA042442: AB_2678001" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (8.49e-4)" "unprognostic (1.10e-1)" "unprognostic (2.91e-1)" "unprognostic (2.80e-3)" "unprognostic (6.87e-4)" "unprognostic (2.53e-1)" "unprognostic (1.69e-1)" "unprognostic (3.57e-3)" "unprognostic (1.17e-2)" "unprognostic (3.33e-16)" "unprognostic (3.02e-3)" "unprognostic (3.14e-1)" "unprognostic (2.83e-2)" 0.0 0.0 0.2 0.6 0.0 0.1 0.0 11.7 1.2 0.0 0.0 1.4 0.1 0.1 0.0 0.1 0.0 3.4 0.1 0.6 0.0 0.8 0.0 0.0 0.0 2.7 0.2 0.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.1 1.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.1 6.1 21.8 0.0 64.1 120.0 16.5 12.2 0.0 0.1 0.0 0.0 88.0 1.2 0.1 0.1 22.5 88.0 0.0 1.1 0.2 0.1 0.0 1.7 0.6 0.0 6.3 0.0 48.6 23.0 27.9 5.7 0.0 0.0 0.2 81.1 0.0 0.1 0.3 0.1 0.0 2.1 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.8 0.0 0.0 0.2 20.9 109.5 4.6 5.4 55.0 0.0 0.0 0.1 6.3 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 11.7 1.2 0.6 0.0 2.7 0.2 3.0 0.0 0.5 0.5 0.0 0.0 1.1 0.3 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.6 0.0 0.1 0.0 0.0 0.0 9.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 4.1 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 FGF6 ENSG00000111241 "Fibroblast growth factor 6" P10767 12 4428155-4445614 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "skeletal muscle: 16.0;tongue: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 2.4;REH: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "unprognostic (4.29e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 2.4 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 63.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 216.6;Leydig cells: 83.3;Proximal tubular cells: 53.4;Smooth muscle cells: 71.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 112.1;ASC TERT1: 66.1;BJ: 45.6;fHDF/TERT166: 50.3;HSkMC: 84.8;RH-30: 119.7;U-138 MG: 56.5" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" 43.8 4.5 3.4 31.5 3.9 0.1 8.5 4.2 5.2 29.4 2.1 11.1 3.7 29.2 4.3 9.5 15.4 46.0 10.5 3.3 4.8 4.5 1.4 12.9 8.3 4.6 4.6 13.4 2.2 3.6 2.2 23.5 5.1 16.2 9.6 8.4 5.1 12.0 2.2 2.6 3.6 26.9 4.1 1.8 5.5 2.3 4.5 3.0 7.4 23.8 4.8 63.3 10.3 4.5 0.2 0.0 0.2 0.3 112.1 66.1 0.1 45.6 25.7 0.0 0.1 0.0 0.3 0.2 0.2 50.3 0.4 0.9 0.0 0.3 0.0 0.1 0.2 0.0 0.5 0.0 10.6 0.3 0.1 84.8 0.8 9.4 0.0 0.3 0.0 0.0 0.1 0.3 5.4 0.1 0.0 0.1 0.2 0.1 0.3 0.1 119.7 0.1 0.1 0.1 1.8 0.6 0.4 0.0 0.4 0.2 0.2 0.2 0.2 56.5 0.5 1.1 0.2 0.5 0.4 0.0 13.3 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.9 4.2 5.2 3.3 4.8 4.6 4.6 5.1 4.1 4.5 4.5 16.1 12.8 19.3 2.0 2.2 14.4 16.8 1.3 1.2 7.9 11.1 9.5 46.8 7.2 0.5 9.2 2.1 6.2 3.2 0.2 119.3 2.0 3.3 8.8 46.2 5.2 0.0 2.7 1.9 0.6 3.3 216.6 2.0 29.2 1.3 0.6 1.8 2.7 2.0 3.3 3.3 0.0 2.0 1.6 15.9 4.0 83.3 1.9 7.2 1.0 0.2 9.8 2.1 1.5 2.9 0.6 0.0 4.9 0.7 9.4 0.0 53.4 0.3 6.1 6.6 43.6 71.6 0.6 0.7 1.8 12.6 2.9 2.9 2.9 0.1 8.4 FGF8 AIGF ENSG00000107831 "Fibroblast growth factor 8" P55075 10 101770130-101780369 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "skeletal muscle: 48.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.1;testis cancer: 3.3" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 17 "RH-30: 37.8" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.56e-1)" "unprognostic (3.90e-3)" "unprognostic (1.12e-2)" "unprognostic (4.88e-1)" "unprognostic (2.47e-2)" "unprognostic (9.09e-2)" "unprognostic (8.75e-3)" "unprognostic (8.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.95e-2)" "unprognostic (1.17e-2)" "unprognostic (2.35e-9)" "unprognostic (6.17e-3)" "unprognostic (9.01e-2)" "unprognostic (1.97e-1)" 0.5 0.0 0.7 0.0 0.7 0.2 0.2 0.6 1.2 0.1 0.8 0.2 0.3 0.2 0.2 0.9 0.1 0.3 0.3 0.9 1.1 0.1 0.1 0.3 0.3 0.5 0.7 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.1 0.5 0.0 0.1 48.7 0.2 0.0 0.0 0.4 0.6 0.1 1.1 0.7 0.0 0.2 0.0 0.0 0.2 0.0 1.0 0.6 0.1 0.3 1.4 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.6 0.7 0.4 0.6 0.0 0.0 0.5 0.3 0.0 0.0 1.1 1.0 0.4 0.3 0.5 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.1 0.0 1.0 0.3 0.9 0.0 0.4 0.6 2.2 0.2 0.0 0.1 0.6 37.8 0.8 0.0 0.2 0.9 0.9 0.0 0.6 0.5 0.0 0.6 0.1 0.6 0.6 1.1 0.8 0.2 0.2 0.8 1.3 0.8 0.7 0.8 1.9 0.4 0.5 0.3 0.5 0.6 0.4 0.4 0.4 0.4 0.5 0.6 0.5 1.1 0.7 0.9 0.4 0.5 0.3 0.7 0.7 0.6 1.2 0.9 1.1 0.5 0.7 0.6 0.4 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 FGFBP1 "FGFBP, HBP17" ENSG00000137440 "Fibroblast growth factor binding protein 1" Q14512 4 15935577-15938740 "Cancer-related genes, Predicted secreted proteins" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 117.1;esophagus: 421.8;vagina: 172.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1044.3;Basal respiratory cells: 596.2;Squamous epithelial cells: 528.5;Suprabasal keratinocytes: 786.2;Urothelial cells: 303.6" "Group enriched" "Detected in many" 5 "cervical cancer: 117.5;head and neck cancer: 246.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 556.3;HBEC3-KT: 968.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA004332 Enhanced "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA004332: AB_1078856" "unprognostic (2.87e-3)" "unprognostic (3.55e-1)" "unprognostic (5.03e-2)" "unprognostic (6.99e-2)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (5.03e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-2)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (3.31e-3)" 0.6 0.1 0.0 1.7 0.0 0.1 13.5 0.0 0.0 117.1 0.0 22.1 1.8 0.5 0.1 421.8 1.2 0.3 0.2 0.0 0.0 0.5 0.1 3.2 0.0 0.0 0.0 0.1 0.4 0.0 0.2 1.1 0.0 1.7 15.6 0.0 59.7 0.1 0.1 91.2 7.0 1.1 0.0 0.1 2.0 0.0 0.0 0.3 0.7 0.0 38.4 14.9 172.3 0.0 150.7 10.5 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 189.0 0.0 10.9 0.0 0.2 556.3 0.0 968.2 0.0 0.0 1.2 0.0 2.0 0.0 0.2 0.0 0.4 0.1 141.0 0.0 17.7 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 7.9 75.2 0.0 0.0 0.0 93.4 6.7 0.0 0.0 0.2 0.0 0.2 0.0 0.9 0.5 0.1 0.2 0.3 0.0 0.3 0.0 0.1 0.2 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 8.4 0.0 0.3 1044.3 182.5 596.2 217.4 0.0 11.8 3.2 0.1 0.0 223.2 0.0 0.0 0.2 0.2 49.6 0.0 49.7 0.0 52.8 3.3 6.3 0.0 0.0 0.0 7.5 2.4 6.2 0.0 65.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 26.1 42.7 0.0 60.6 0.0 0.0 0.9 74.7 0.0 0.6 0.0 1.0 0.0 0.0 139.1 50.8 0.0 0.0 90.8 0.7 0.0 56.8 0.0 0.0 0.0 10.4 0.0 0.0 528.5 786.2 2.3 2.1 0.0 26.1 303.6 FGFBP2 KSP37 ENSG00000137441 "Fibroblast growth factor binding protein 2" Q9BYJ0 4 15960245-15969309 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.0;bone marrow: 54.6" "Group enriched" "Detected in many" 6 "dendritic cells: 486.6;NK-cells: 1627.2" "Group enriched" "Detected in many" 9 "glioma: 4.8;head and neck cancer: 13.1;lung cancer: 16.7;melanoma: 16.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 551.3;memory CD8 T-cell: 332.1" "Lineage enriched" "Detected in many" 8 "T-cells: 551.3" "Cell line enhanced" "Detected in some" "SK-MEL-30: 6.9;T-47d: 3.2;WM-115: 1.3" "Secreted to blood" NA NA 346000000 36000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.51e-3)" "unprognostic (8.81e-3)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-2)" "unprognostic (1.54e-1)" "unprognostic (6.14e-2)" "unprognostic (1.35e-2)" "unprognostic (9.89e-2)" "unprognostic (1.76e-1)" "unprognostic (2.55e-2)" "unprognostic (3.33e-1)" "unprognostic (3.51e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (9.61e-2)" "unprognostic (1.49e-2)" 29.0 1.5 0.9 0.4 1.0 54.6 12.7 0.8 1.5 0.6 0.8 11.8 0.1 0.5 7.2 0.6 0.7 0.9 23.6 1.0 1.1 0.5 1.2 8.5 2.9 0.9 0.8 0.4 0.2 0.3 0.2 0.5 0.9 1.4 0.9 1.1 8.6 0.9 1.1 21.0 2.0 0.3 0.8 14.0 1.7 8.6 0.9 5.3 1.1 3.6 1.0 2.8 1.8 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 6.9 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.3 3.5 0.8 2.4 551.3 1.3 5.2 0.8 128.6 332.1 0.9 0.4 47.3 314.1 8.4 64.9 1.6 2.1 0.9 371.2 0.9 1.0 0.8 1.5 1.0 1.1 0.9 0.8 0.9 0.8 0.9 0.9 2.6 0.0 5.3 0.0 2.6 9.6 0.0 0.2 0.0 0.0 1.5 1.7 1.5 5.7 1.4 5.5 8.4 0.6 486.6 0.1 0.0 0.7 1.3 0.9 0.1 2.2 0.0 3.6 0.0 0.0 0.0 19.9 0.5 0.3 3.8 60.3 6.1 0.6 0.0 0.0 0.0 0.4 0.0 4.9 12.0 3.0 0.0 2.2 46.2 0.0 5.8 1.4 1627.2 0.0 0.1 0.2 0.0 0.4 17.5 0.0 0.0 1.3 1.3 0.4 0.0 1.8 2.5 0.7 0.1 0.1 7.7 1.0 167.2 0.2 0.1 0.0 FGFBP3 "C10orf13, MGC39320" ENSG00000174721 "Fibroblast growth factor binding protein 3" Q8TAT2 10 91906584-91909486 "Predicted secreted proteins" "Growth factor binding, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 19.6;Enteroendocrine cells: 46.2;Muller glia cells: 28.2" "Cancer enhanced" "Detected in many" "glioma: 4.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.7" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 9 "AF22: 315.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA053943 Uncertain "Secreted in brain" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA053943: AB_2682318" "unprognostic (8.66e-2)" "unprognostic (6.00e-2)" "unprognostic (4.47e-2)" "unprognostic (2.88e-1)" "unprognostic (9.98e-3)" "unprognostic (7.76e-2)" "unprognostic (1.43e-1)" "unprognostic (1.96e-2)" "unprognostic (1.06e-1)" "unprognostic (1.12e-1)" "unprognostic (3.39e-3)" "unprognostic (2.61e-1)" "unprognostic (3.90e-1)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "unprognostic (2.63e-1)" "unprognostic (6.76e-3)" 1.0 1.4 3.9 0.8 3.6 0.6 1.1 3.0 4.4 1.5 2.0 1.0 0.6 1.4 1.5 0.9 1.1 0.2 0.9 3.3 4.3 1.6 0.6 0.7 0.8 4.1 3.7 1.4 1.9 0.9 2.2 0.4 3.7 1.7 1.0 4.5 1.5 0.6 2.0 1.3 1.1 0.4 3.3 1.3 1.2 0.5 4.0 0.8 2.3 0.6 0.6 1.5 1.1 4.0 0.3 2.5 315.8 4.7 1.3 0.4 1.1 0.2 0.2 0.6 1.0 0.8 1.2 0.4 0.4 0.6 0.1 1.3 2.2 0.3 0.8 1.2 3.4 6.5 2.6 3.8 0.7 35.5 0.9 0.9 0.4 1.6 1.5 1.0 0.2 4.1 3.4 1.2 0.1 2.7 4.1 14.2 23.4 1.3 1.1 10.5 2.0 0.5 0.5 0.8 3.3 4.3 0.8 0.1 5.7 1.8 1.3 0.7 0.3 0.3 2.3 0.4 1.1 0.8 2.0 1.3 0.3 4.1 0.6 0.6 0.1 0.0 0.5 0.0 0.1 0.8 0.3 0.2 0.1 1.7 0.5 0.4 0.0 0.3 0.0 0.1 0.0 0.0 3.9 3.6 3.0 4.4 3.3 4.3 4.1 3.7 3.7 3.3 4.0 4.0 2.8 0.0 2.0 2.6 2.9 1.3 5.1 0.3 1.2 13.0 5.4 5.1 3.2 4.3 2.9 5.5 2.1 2.9 4.4 1.7 19.6 2.0 0.3 1.4 1.9 2.6 46.2 2.1 1.9 3.4 1.1 3.8 5.1 1.3 0.0 3.2 3.3 1.5 1.4 6.7 2.7 7.6 0.0 3.4 2.6 0.5 5.9 2.5 3.6 1.0 2.5 28.2 10.3 5.5 2.6 0.6 2.4 3.8 3.1 3.2 1.0 3.2 4.9 15.9 0.0 4.6 3.1 0.3 1.0 4.7 2.7 1.0 6.4 2.6 3.8 4.3 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 176.7;Leydig cells: 192.0;Oligodendrocyte precursor cells: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 508.7;BJ hTERT+: 278.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 95.1 12.8 27.5 15.9 24.6 14.1 87.1 48.8 22.4 79.8 37.2 97.2 8.8 74.2 15.8 35.8 85.9 57.1 89.9 30.9 28.8 40.1 9.1 55.7 16.6 35.9 37.3 108.2 98.6 20.4 57.1 51.3 63.7 60.5 17.9 15.8 31.4 53.6 24.8 35.6 41.7 57.1 30.3 9.9 40.4 20.4 33.4 17.1 33.7 23.3 16.1 79.3 63.9 29.6 12.9 42.0 198.0 508.7 120.1 91.2 142.9 136.7 278.8 90.0 95.8 27.3 6.5 1.8 38.3 127.7 103.9 0.2 90.0 6.8 104.3 39.2 24.1 0.0 7.7 27.8 69.7 31.1 0.6 80.5 0.7 70.9 13.3 45.6 86.9 6.0 11.9 0.4 40.5 12.5 91.5 9.2 145.9 1.6 21.6 86.3 21.1 0.4 35.6 0.3 7.9 19.4 23.4 1.0 5.1 93.4 9.3 5.4 51.4 49.2 28.9 149.6 29.7 2.4 4.1 0.5 60.3 1.7 27.1 0.2 0.3 0.1 1.7 0.1 1.1 0.3 0.7 1.2 0.0 0.6 0.5 1.5 0.6 0.4 0.2 0.2 1.0 0.1 27.5 24.6 48.8 22.4 30.9 28.8 35.9 37.3 63.7 30.3 33.4 29.6 101.0 3.2 15.8 55.8 1.8 31.5 95.9 1.1 37.0 4.4 28.7 77.7 52.5 24.3 5.1 9.2 4.2 8.3 6.3 0.4 0.0 27.3 15.3 48.2 40.6 75.5 25.0 3.6 25.4 65.2 80.5 176.7 3.1 75.3 8.2 40.4 47.5 0.8 25.3 21.9 21.1 0.6 4.1 5.6 75.2 15.0 192.0 11.7 33.8 19.7 1.7 88.1 6.2 166.4 14.2 21.6 0.3 99.6 6.4 94.7 0.1 7.9 1.0 3.3 13.1 118.9 59.9 1.6 14.1 4.8 19.7 10.4 14.1 2.1 0.7 11.7 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 148.3;esophagus: 139.7;skin 1: 271.5" "Cell type enhanced" "Detected in many" "Astrocytes: 410.4;Basal keratinocytes: 103.8;Cholangiocytes: 91.5;Suprabasal keratinocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 48.2;HaCaT: 34.9;Hep G2: 80.6;NTERA-2: 36.1;RT4: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" NA NA 2500000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: AB_2685804" "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" 1.6 1.6 118.0 1.5 140.6 1.4 5.5 115.6 104.0 23.7 37.4 12.2 19.5 1.5 2.8 139.7 2.2 7.9 4.8 100.8 107.6 39.3 40.7 7.4 0.4 144.7 129.2 0.5 76.4 0.2 16.1 9.3 109.8 13.8 5.2 0.2 20.2 15.0 1.3 271.5 14.7 0.4 108.9 4.0 7.8 17.6 148.3 1.7 1.5 0.9 11.1 23.1 60.9 81.2 0.0 3.8 19.5 5.6 0.0 0.3 22.1 2.4 0.3 0.8 0.4 48.2 1.0 0.0 17.8 0.7 0.7 34.9 5.5 0.3 0.3 0.2 19.3 14.2 3.9 80.6 0.1 0.0 0.6 0.0 10.9 0.2 0.1 0.1 0.1 2.3 16.7 0.1 0.0 23.9 0.8 0.5 36.1 19.5 0.1 1.2 1.0 0.3 2.8 64.1 5.7 1.6 1.9 4.0 0.0 22.2 20.4 2.5 1.0 0.0 2.1 0.5 1.6 0.1 0.0 0.0 0.2 1.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 118.0 140.6 115.6 104.0 100.8 107.6 144.7 129.2 109.8 108.9 148.3 81.2 2.2 0.0 32.5 410.4 1.1 103.8 4.1 29.8 23.9 0.0 4.8 1.5 3.1 91.5 37.6 14.7 0.0 0.5 1.6 36.1 0.0 5.0 7.9 3.0 1.7 3.4 4.2 0.0 0.5 0.7 12.0 3.2 3.6 4.0 0.0 0.1 16.1 30.4 0.6 0.0 1.3 20.7 4.1 1.2 6.5 1.3 0.6 0.6 12.4 14.0 0.6 0.1 0.0 34.2 2.2 0.4 18.0 0.4 0.0 4.2 21.2 9.9 9.8 0.6 0.0 0.7 2.9 0.4 25.9 55.0 88.7 0.8 0.7 0.1 17.0 12.8 FGFR4 "CD334, JTK2" ENSG00000160867 "Fibroblast growth factor receptor 4" P22455 5 177086905-177098144 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 82.5;lung: 65.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 78.6;Hepatocytes: 31.2;Skeletal myocytes: 141.2;Theca cells: 36.7;Undifferentiated cells: 38.6" "Cancer enhanced" "Detected in many" "liver cancer: 42.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CACO-2: 173.9;Hep G2: 176.4;RH-30: 274.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005196, HPA027273, HPA027369, HPA028251" Approved "Intracellular and membrane" NA NA 7400000 "Cluster 18: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB005196: AB_631512, HPA027273: AB_10600212, HPA027369: AB_10599427, HPA028251: AB_10601221" "unprognostic (1.96e-1)" "unprognostic (2.10e-2)" "unprognostic (1.12e-1)" "unprognostic (9.06e-3)" "unprognostic (2.87e-1)" "unprognostic (1.95e-2)" "unprognostic (7.85e-3)" "unprognostic (9.19e-2)" "unprognostic (4.25e-1)" "unprognostic (4.46e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" 1.2 14.0 1.1 4.1 1.1 0.5 4.5 2.7 2.1 3.0 1.2 18.0 21.3 2.4 0.2 3.2 4.2 10.2 2.2 1.4 1.0 40.2 82.5 65.4 0.8 0.7 0.8 27.5 29.5 0.2 2.0 2.1 0.9 5.2 6.0 1.5 1.1 0.7 6.6 1.7 20.0 1.1 0.7 22.7 8.8 5.9 1.1 0.2 0.9 1.9 0.2 6.4 3.2 1.3 3.2 48.8 1.0 11.7 0.1 0.1 24.5 0.2 0.1 0.2 0.3 173.9 6.5 5.3 23.0 0.1 2.4 2.8 9.5 1.8 0.1 3.2 13.8 0.5 2.8 176.4 5.2 0.6 4.7 1.1 0.2 8.4 0.2 0.3 0.2 3.5 18.1 0.7 3.9 40.3 0.1 3.6 29.2 30.9 4.5 8.2 274.3 30.9 22.9 0.4 1.8 2.9 1.8 12.4 5.9 5.9 11.7 2.5 1.1 0.0 23.4 0.3 0.7 1.6 1.9 3.7 0.1 1.1 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.1 1.1 2.7 2.1 1.4 1.0 0.7 0.8 0.9 0.7 1.1 1.3 0.3 0.0 0.0 0.3 0.3 0.6 0.7 0.4 0.0 0.9 2.9 2.0 0.9 78.6 0.1 3.7 0.0 1.3 0.1 12.9 3.9 10.9 0.1 1.6 0.3 0.7 4.2 0.0 0.5 4.9 3.8 9.6 9.7 2.9 0.0 0.7 3.9 31.2 0.3 0.0 0.5 10.1 0.0 0.9 0.5 0.0 0.6 0.7 0.0 1.9 0.6 0.6 0.0 0.5 0.1 3.0 4.4 1.5 0.1 1.7 15.9 21.6 0.1 0.4 19.7 141.2 0.7 3.0 9.9 0.8 0.4 8.8 0.4 36.7 38.6 0.5 FGFRL1 ENSG00000127418 "Fibroblast growth factor receptor like 1" Q8N441 4 1009936-1026898 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 34.0;Granulosa cells: 30.9;Hepatocytes: 37.5;Muller glia cells: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.1;non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-251 MG: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026019, HPA068828" Approved Supported Vesicles No No "Cluster 7: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "CAB026019: , HPA068828: AB_2686043" "unprognostic (1.30e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "unprognostic (2.80e-2)" "unprognostic (1.23e-2)" "unprognostic (1.48e-1)" "unprognostic (2.62e-2)" "unprognostic (9.79e-2)" "unprognostic (4.87e-3)" "unprognostic (8.46e-2)" "unprognostic (2.01e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-3)" "unprognostic (1.49e-1)" "unprognostic (7.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.96e-2)" 38.1 56.0 40.8 5.0 43.3 7.6 24.1 40.6 49.5 15.7 29.8 10.2 7.3 9.9 3.4 5.5 36.0 9.3 19.8 39.2 33.5 25.4 52.8 15.1 3.1 49.9 45.8 25.4 71.6 16.1 21.6 3.0 46.5 12.4 4.9 10.5 37.6 2.7 20.6 10.7 13.5 4.0 42.2 9.1 27.2 5.5 47.9 1.4 67.1 9.6 2.2 11.2 8.0 42.1 23.2 31.6 11.3 34.3 11.9 12.3 2.9 40.4 6.2 12.9 8.4 23.1 47.9 2.6 49.3 63.3 58.3 5.8 21.8 14.1 11.8 8.3 21.0 0.3 41.2 61.5 24.0 13.7 5.6 25.7 11.7 22.4 9.5 48.4 12.5 9.3 25.3 8.9 7.9 30.8 16.0 37.7 14.2 39.7 83.8 24.7 16.3 16.7 22.6 3.6 1.2 2.2 38.1 0.8 15.2 13.4 22.5 11.9 26.1 68.8 27.2 35.2 99.8 8.9 12.9 3.8 18.1 15.6 22.8 0.6 0.0 0.0 0.2 1.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.1 40.8 43.3 40.6 49.5 39.2 33.5 49.9 45.8 46.5 42.2 47.9 42.1 3.8 3.2 4.1 34.0 2.8 6.5 3.7 5.4 2.2 5.4 13.2 6.1 8.5 11.5 6.9 7.3 0.0 1.6 4.1 4.4 0.0 9.6 0.2 6.0 4.2 2.6 1.8 4.8 3.2 10.2 26.6 5.1 6.6 13.5 1.3 30.9 5.3 37.5 3.2 0.0 2.8 11.0 0.0 1.6 2.5 1.2 4.4 3.4 7.2 1.9 1.3 94.0 1.0 5.0 5.4 19.9 2.7 3.4 2.2 11.4 2.9 7.6 7.0 5.6 0.0 3.3 5.1 0.4 4.2 1.2 4.7 1.5 4.2 17.5 3.6 8.8 FGG ENSG00000171557 "Fibrinogen gamma chain" P02679 4 154604134-154612967 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 330 "liver: 16556.3" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 10221.7" "Cancer enriched" "Detected in many" 19 "liver cancer: 1503.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "Hep G2: 735.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027529, CAB033120, HPA074638" Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 267000000000 73000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB033120: AB_2103818, HPA027529: AB_10601322, HPA074638: " "unprognostic (1.26e-2)" "unprognostic (4.77e-3)" "unprognostic (6.33e-3)" "unprognostic (3.69e-3)" "unprognostic (2.18e-3)" "unprognostic (9.63e-2)" "unprognostic (7.57e-3)" "prognostic unfavorable (1.00e-6)" "unprognostic (1.75e-3)" "unprognostic (3.21e-1)" "unprognostic (1.14e-1)" 1.7 34.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.3 0.0 0.4 0.0 0.4 0.2 0.6 0.7 25.0 1.2 0.0 0.0 8.8 16556.3 50.2 0.1 0.0 0.0 1.4 15.8 0.0 0.4 6.3 0.0 0.4 0.0 0.0 0.4 0.3 0.4 0.5 0.6 0.0 0.0 9.1 8.7 3.0 0.1 0.3 0.4 0.0 0.0 0.5 0.6 0.1 0.0 13.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.2 0.0 1.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.5 0.4 735.3 0.2 8.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.3 0.0 0.6 0.0 0.0 0.3 6.4 0.0 0.0 0.6 0.0 0.0 5.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.1 0.1 1.7 0.0 3.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 19.2 214.4 0.0 31.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 633.4 2.5 0.0 0.0 0.0 0.0 0.1 0.0 21.9 4.3 0.0 0.1 9.2 0.0 157.7 0.0 48.5 0.2 0.5 0.0 0.1 11.4 1.1 202.4 10221.7 0.2 0.0 0.0 0.0 0.0 289.5 0.0 0.5 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 161.8 0.0 0.0 0.0 0.0 0.0 1.6 1.5 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.0 0.4 17.3 0.2 0.0 0.0 FGL1 "HFREP-1, HPS" ENSG00000104760 "Fibrinogen like 1" Q08830 8 17864380-17910365 "Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 4163.9" "Cell type enriched" "Detected in many" 27 "Hepatocytes: 8261.7" "Cancer enriched" "Detected in some" 40 "liver cancer: 399.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "A549: 55.4;Hep G2: 131.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 57000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (3.62e-2)" "unprognostic (1.14e-2)" "unprognostic (1.75e-5)" "unprognostic (3.00e-1)" "unprognostic (3.54e-2)" "unprognostic (7.89e-2)" "unprognostic (2.15e-1)" "unprognostic (2.62e-1)" "unprognostic (2.71e-1)" "unprognostic (1.09e-2)" "unprognostic (2.86e-7)" "prognostic unfavorable (5.38e-4)" "unprognostic (3.62e-1)" "unprognostic (2.58e-2)" "unprognostic (1.35e-1)" 0.9 0.4 1.2 0.0 1.4 0.0 1.0 1.0 1.8 0.4 0.9 0.2 0.0 0.7 0.7 0.2 0.2 0.1 0.3 1.3 1.7 0.5 4163.9 1.2 0.0 1.3 1.6 0.3 660.1 0.0 0.2 6.3 1.3 3.8 0.1 0.2 0.2 0.0 0.1 0.1 0.3 0.2 1.1 3.8 0.6 4.3 1.5 0.0 0.3 0.0 0.0 0.1 0.1 1.2 0.0 55.4 0.0 6.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 131.9 0.0 1.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.2 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 1.3 0.8 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.4 1.0 1.8 1.3 1.7 1.3 1.6 1.3 1.1 1.5 1.2 0.0 0.0 1.9 12.4 24.6 0.0 0.2 0.0 0.0 0.0 1.3 0.9 2.1 301.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 8.3 42.9 5.4 1.0 7.6 0.0 176.4 0.1 71.2 0.4 0.1 0.0 7.8 0.0 0.0 173.8 8261.7 20.4 0.0 0.3 0.0 0.0 231.6 0.0 32.7 0.6 0.2 0.0 14.0 1.6 0.0 0.0 2.5 0.0 74.1 0.0 0.4 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.7 0.0 0.0 1.0 12.8 0.1 0.3 0.2 FGL2 "pT49, T49" ENSG00000127951 "Fibrinogen like 2" Q14314 7 77193369-77199848 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 162.5" "Group enriched" "Detected in many" 4 "Kupffer cells: 466.3;Langerhans cells: 571.0;Macrophages: 430.3;monocytes: 463.1;Skeletal myocytes: 166.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 45 "classical monocyte: 256.5;eosinophil: 226.3;intermediate monocyte: 380.6;myeloid DC: 160.0;neutrophil: 294.7;non-classical monocyte: 379.8" "Group enriched" "Detected in all" 59 "dendritic cells: 160.0;granulocytes: 294.7;monocytes: 380.6" "Cell line enhanced" "Detected in some" "Karpas-707: 2.0;LHCN-M2: 2.9;NB-4: 2.9;RPTEC TERT1: 5.0;THP-1: 2.1;U-937: 5.0;WM-115: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021011, HPA026682" Enhanced "Secreted to blood" NA NA 38800000 7800000 "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "HPA021011: AB_1848532, HPA026682: AB_1848533" "unprognostic (9.80e-3)" "unprognostic (4.70e-3)" "unprognostic (1.19e-1)" "unprognostic (3.51e-3)" "unprognostic (1.62e-1)" "unprognostic (1.00e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-2)" "unprognostic (3.49e-1)" "unprognostic (2.70e-1)" "unprognostic (3.19e-1)" "unprognostic (1.27e-1)" "unprognostic (1.19e-1)" "unprognostic (5.00e-2)" "unprognostic (1.91e-2)" "unprognostic (2.33e-1)" "unprognostic (7.01e-2)" 48.5 24.4 3.3 89.4 2.7 5.8 35.1 5.3 3.5 17.2 6.1 44.9 43.7 17.8 7.6 38.5 22.1 45.4 21.6 2.4 5.4 44.9 43.5 32.7 56.5 7.7 5.9 10.9 8.3 5.2 7.9 21.6 6.7 10.5 57.2 0.8 14.8 11.7 8.8 13.9 69.8 45.7 6.2 162.5 23.5 6.2 3.9 30.1 18.8 24.6 27.5 73.3 7.1 9.8 0.0 0.0 0.0 0.0 1.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.9 0.0 0.0 2.9 0.1 0.0 0.0 0.1 0.2 0.3 5.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 5.0 5.7 2.8 256.5 226.3 3.9 380.6 1.2 4.3 2.5 3.4 160.0 2.0 1.8 3.0 294.7 2.5 379.8 6.2 4.7 174.0 3.3 2.7 5.3 3.5 2.4 5.4 7.7 5.9 6.7 6.2 3.9 9.8 102.0 6.4 12.1 0.0 26.2 38.1 1.1 0.1 3.4 1.1 1.4 3.0 4.4 0.0 5.0 88.3 10.4 1.3 60.3 17.3 5.9 1.9 7.5 2.6 0.7 50.6 0.0 7.0 0.3 0.0 1.4 102.8 2.0 5.0 10.1 0.6 45.3 5.2 36.2 1.7 0.4 0.3 0.0 466.3 571.0 9.4 27.7 430.3 49.8 33.7 463.1 13.6 39.1 0.0 0.9 0.1 10.9 19.5 82.6 1.1 42.5 5.9 2.2 7.4 0.0 166.2 8.2 0.4 0.4 2.1 31.3 3.7 24.1 0.2 0.8 1.5 FHL1 "bA535K18.1, FHL1B, FLH1A, KYO-T, MGC111107, SLIM1, XMPMA" ENSG00000022267 "Four and a half LIM domains 1" Q13642 X 136146702-136211359 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 11467.1;tongue: 9770.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1145.1;Early spermatids: 373.8;Late spermatids: 1206.9" "Cancer enhanced" "Detected in all" "renal cancer: 88.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 36.1" "Group enriched" "Detected in many" 4 "dendritic cells: 19.4;NK-cells: 36.1;T-cells: 18.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 303.7;fHDF/TERT166: 258.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001040, HPA001391, CAB020817" Enhanced Supported "Plasma membrane,Cytosol" NA NA 12000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "CAB020817: , HPA001040: AB_1848541, HPA001391: AB_1848542" "unprognostic (2.16e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.61e-3)" "unprognostic (1.76e-2)" "unprognostic (2.51e-2)" "unprognostic (9.34e-2)" "unprognostic (7.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (1.72e-1)" "unprognostic (6.17e-3)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.05e-3)" "prognostic unfavorable (2.11e-4)" 938.4 65.8 120.8 75.5 117.2 11.7 441.8 95.9 126.3 315.5 85.8 672.0 83.2 464.6 107.7 538.1 281.6 127.6 1462.3 130.8 144.9 45.2 43.1 285.6 41.7 103.9 125.4 102.8 39.4 196.5 92.9 106.6 115.9 408.8 161.4 76.2 161.3 541.1 11467.1 101.3 235.5 486.5 114.8 43.0 368.4 60.2 130.1 25.1 310.1 9770.8 32.1 469.6 253.1 102.9 0.4 44.3 60.7 57.8 127.2 52.3 1.5 183.7 303.7 34.8 81.3 0.3 12.7 0.7 55.8 258.8 95.0 0.5 119.2 148.0 28.2 0.4 136.7 0.7 34.4 0.0 121.6 0.3 26.8 96.6 24.4 41.2 128.7 14.1 36.6 34.5 0.1 26.0 81.9 2.5 26.1 1.6 19.1 0.2 52.2 69.8 2.6 38.2 1.1 0.1 43.5 63.8 6.6 0.2 12.4 24.1 0.3 2.4 102.5 150.2 71.0 5.9 44.7 6.8 16.0 1.1 11.9 1.4 18.2 0.1 0.7 0.0 5.2 0.1 13.8 5.8 18.2 7.2 3.1 3.6 12.0 4.0 1.2 36.1 0.0 19.4 2.2 11.1 120.8 117.2 95.9 126.3 130.8 144.9 103.9 125.4 115.9 114.8 130.1 102.9 203.0 48.1 11.7 32.0 8.1 56.5 26.9 15.1 14.2 36.2 1.4 8.3 1145.1 0.0 4.9 11.0 8.4 0.6 8.6 0.5 1.9 3.0 373.8 4.3 32.3 61.1 13.8 17.9 70.2 0.2 1.1 236.0 2.0 2.0 15.8 41.0 113.6 6.1 4.3 99.3 55.6 0.8 0.0 5.1 47.0 1206.9 123.9 35.6 32.0 16.9 7.4 209.6 2.1 35.2 8.2 0.6 7.6 152.4 15.5 20.1 0.6 11.6 4.8 19.4 105.2 248.1 235.7 7.4 88.6 2.7 44.8 2.7 15.5 9.6 2.0 2.6 FHOD3 "FHOS2, FLJ22297, FLJ22717, KIAA1695" ENSG00000134775 "Formin homology 2 domain containing 3" Q2V2M9 18 36297714-36780055 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 172.8" "Cell type enhanced" "Detected in many" "Astrocytes: 104.5;Cone photoreceptor cells: 87.6;Excitatory neurons: 132.2;Granulosa cells: 84.9;Inhibitory neurons: 186.5;Oligodendrocyte precursor cells: 114.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 72.3;HDLM-2: 80.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021827, HPA024696" Uncertain "Intracellular and membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA021827: AB_1848571, HPA024696: AB_1848573" "unprognostic (8.46e-2)" "unprognostic (8.76e-2)" "unprognostic (6.34e-2)" "unprognostic (3.44e-1)" "unprognostic (8.96e-2)" "unprognostic (8.30e-2)" "unprognostic (4.11e-4)" "unprognostic (2.73e-2)" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (2.16e-3)" "unprognostic (4.55e-2)" "prognostic favorable (1.19e-5)" "unprognostic (1.64e-2)" "unprognostic (4.10e-2)" "unprognostic (3.00e-3)" "unprognostic (1.20e-1)" 3.4 32.1 13.2 2.4 14.3 0.1 6.1 8.7 17.7 5.6 13.9 14.5 1.6 3.0 42.2 9.4 11.2 7.2 172.8 13.8 12.3 23.2 1.4 1.5 1.3 37.9 15.1 6.9 2.1 1.0 10.5 1.3 36.8 27.9 3.4 36.1 11.3 62.8 49.5 6.5 5.5 10.1 11.5 1.3 3.2 4.1 8.5 2.4 3.6 20.5 4.0 14.6 5.2 13.5 15.5 5.4 34.3 8.2 0.2 0.0 2.6 34.1 72.3 6.7 6.5 0.0 24.5 2.8 8.9 16.3 19.2 19.5 11.4 14.8 4.0 80.1 4.0 0.0 1.0 0.1 0.4 0.0 1.1 4.5 7.1 3.6 1.5 36.6 0.2 0.0 0.0 0.2 8.0 0.0 0.1 0.2 7.5 0.0 4.9 0.0 0.0 18.9 32.5 17.0 19.0 44.6 7.4 0.1 4.6 3.0 0.2 0.1 39.6 21.3 1.6 0.9 29.5 31.8 0.0 0.0 23.8 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 14.3 8.7 17.7 13.8 12.3 37.9 15.1 36.8 11.5 8.5 13.5 0.4 0.0 0.0 104.5 0.0 3.2 0.9 8.9 14.8 6.5 2.3 11.4 38.0 0.0 2.7 12.9 87.6 0.1 0.0 0.2 3.9 1.3 1.7 10.2 1.7 0.6 0.0 0.4 132.2 0.9 11.3 7.9 1.1 0.6 0.0 84.9 0.0 0.0 0.2 0.0 186.5 0.2 6.1 0.0 0.6 0.4 0.0 0.3 10.6 11.2 0.0 7.3 0.0 114.1 3.4 3.3 0.1 0.4 0.0 0.6 0.0 7.9 15.3 33.6 0.0 11.2 6.3 2.2 2.8 1.6 0.6 0.4 0.4 29.9 0.3 0.3 FIBCD1 FLJ14810 ENSG00000130720 "Fibrinogen C domain containing 1" Q8N539 9 130902438-130939286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.9;brain: 26.7;parathyroid gland: 12.5" "Cell type enhanced" "Detected in some" "Early spermatids: 19.6;Exocrine glandular cells: 30.1;Intestinal goblet cells: 24.5;Ionocytes: 26.4;Late spermatids: 36.1;Pancreatic endocrine cells: 28.6;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 11 "monocytes: 1.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 13.7;MCF7: 32.8;OE19: 22.9;RPTEC TERT1: 24.4;THP-1: 12.5;U-2 OS: 14.1;U-251 MG: 13.5" "Group enriched" "Detected in many" 4 "basal ganglia: 17.6;hippocampal formation: 68.4" "Region enriched" "Detected in many" 5 "hippocampal formation: 57.3" HPA055353 Approved Approved "Cell Junctions" NA NA 19000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cell Junctions" "HPA055353: AB_2682791" "unprognostic (1.18e-3)" "unprognostic (2.70e-1)" "unprognostic (4.69e-2)" "unprognostic (5.63e-2)" "unprognostic (9.11e-2)" "unprognostic (1.62e-1)" "unprognostic (4.16e-5)" "unprognostic (1.83e-3)" "unprognostic (3.14e-1)" "unprognostic (1.28e-1)" "unprognostic (2.05e-2)" "unprognostic (4.45e-2)" "unprognostic (1.42e-6)" "unprognostic (1.66e-1)" "unprognostic (5.53e-2)" "unprognostic (6.68e-3)" "unprognostic (2.77e-1)" 0.1 9.9 8.0 0.0 1.8 0.0 0.5 0.0 15.8 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 0.2 0.5 26.7 1.4 0.1 0.0 2.1 0.0 8.3 6.3 0.1 0.0 12.5 0.1 0.9 5.2 0.1 0.7 1.3 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.3 0.1 6.6 5.4 0.0 0.0 0.0 0.0 0.9 0.1 2.7 0.3 3.5 1.2 0.0 0.1 0.0 0.0 5.9 8.7 0.4 1.2 0.0 3.7 0.0 2.3 0.3 6.3 2.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.7 0.4 0.2 0.3 0.0 0.1 3.9 0.0 13.7 0.0 0.0 0.7 0.0 0.0 32.8 0.0 2.8 2.1 22.9 0.6 0.0 5.7 0.4 24.4 0.0 0.2 0.0 1.1 0.1 0.8 0.9 2.0 12.5 0.0 1.3 14.1 0.1 13.5 0.0 0.0 0.0 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 8.0 1.8 0.0 15.8 26.7 1.4 8.3 6.3 5.2 0.0 5.4 2.7 0.2 0.0 0.0 0.3 0.0 0.0 0.9 5.0 0.0 3.2 0.8 0.0 1.3 0.0 2.3 1.8 0.0 11.6 0.0 10.4 0.0 0.3 19.6 0.0 0.1 0.4 0.0 0.0 0.3 30.1 0.9 0.9 0.0 0.0 0.0 0.8 0.0 0.0 1.1 3.3 0.3 24.5 26.4 0.0 0.0 36.1 0.6 0.5 0.0 1.9 0.4 0.6 0.0 0.0 0.1 28.6 6.3 3.4 0.0 0.7 2.5 0.1 2.1 0.2 0.0 0.0 0.8 9.5 16.3 0.0 0.0 4.0 0.0 0.9 6.7 1.5 FIBIN MGC24932 ENSG00000176971 "Fin bud initiation factor homolog" Q8TAL6 11 26994112-26997087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 33.0;Fibroblasts: 80.8;Granulosa cells: 42.4;Leydig cells: 37.9;Oligodendrocyte precursor cells: 32.2;Peritubular cells: 35.0" "Cancer enhanced" "Detected in all" "glioma: 48.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 65.2;ASC TERT1: 41.8;fHDF/TERT166: 22.1;HHSteC: 88.2;HSkMC: 89.5;hTCEpi: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040120 Uncertain "Intracellular and membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA040120: AB_10795243" "unprognostic (1.72e-1)" "unprognostic (2.61e-1)" "unprognostic (1.29e-1)" "unprognostic (9.04e-2)" "unprognostic (1.62e-2)" "unprognostic (5.42e-2)" "unprognostic (7.28e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (5.08e-3)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "prognostic favorable (1.93e-5)" "prognostic unfavorable (6.72e-4)" "unprognostic (8.48e-2)" "prognostic unfavorable (1.85e-6)" "unprognostic (1.02e-2)" 32.3 4.9 11.0 7.7 10.6 0.0 25.1 11.4 10.8 35.6 6.1 27.8 2.2 26.1 8.0 11.3 35.7 7.9 32.6 10.8 10.7 15.2 2.0 27.2 2.8 10.6 12.7 18.5 3.8 0.3 2.6 12.6 11.7 17.0 2.6 0.6 17.6 61.3 17.1 16.7 12.0 17.1 11.4 14.1 21.1 1.3 11.6 2.1 13.4 14.5 0.9 16.3 58.3 11.7 0.0 0.0 1.0 0.0 65.2 41.8 0.1 2.1 5.7 0.2 0.9 0.0 0.0 0.0 0.0 22.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 88.2 0.0 0.0 89.5 24.0 1.1 0.0 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 4.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 10.6 11.4 10.8 10.8 10.7 10.6 12.7 11.7 11.4 11.6 11.7 2.5 0.0 0.0 17.9 0.0 6.6 1.6 33.0 1.8 0.3 1.9 0.9 1.2 11.5 4.0 11.0 0.0 1.2 0.0 0.1 11.7 0.6 0.1 0.0 0.1 1.0 0.0 0.0 0.5 0.0 0.9 80.8 0.0 0.0 0.0 42.4 6.1 0.5 1.8 0.0 0.1 0.0 12.2 0.0 10.3 0.3 37.9 0.8 7.2 0.0 0.0 19.8 0.0 32.2 0.1 0.1 0.0 35.0 0.1 0.2 0.0 4.3 0.9 0.6 0.0 3.7 7.4 0.1 0.3 0.8 5.1 1.9 0.5 3.9 0.0 0.0 FICD "HIP13, HYPE" ENSG00000198855 "FIC domain protein adenylyltransferase" Q9BVA6 12 108515277-108525837 "Enzymes, Predicted intracellular proteins" "Unfolded protein response" "Hydrolase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 62.8;Late spermatids: 52.0;Syncytiotrophoblasts: 31.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021390, HPA071134" Approved Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA021390: AB_1851340, HPA071134: AB_2686347" "unprognostic (1.00e-1)" "unprognostic (8.76e-2)" "unprognostic (1.76e-2)" "prognostic favorable (4.61e-5)" "unprognostic (6.92e-2)" "unprognostic (2.68e-2)" "unprognostic (5.73e-2)" "unprognostic (2.84e-2)" "unprognostic (8.68e-2)" "unprognostic (2.57e-1)" "unprognostic (3.15e-2)" "unprognostic (1.19e-1)" "unprognostic (7.66e-2)" "unprognostic (1.56e-2)" "unprognostic (6.22e-2)" "unprognostic (3.12e-2)" "unprognostic (3.65e-2)" 3.5 7.5 5.1 5.3 6.5 2.9 3.6 6.2 5.9 6.3 4.5 3.2 3.3 3.3 12.2 1.8 3.2 3.0 2.7 5.3 6.3 3.0 8.2 3.9 4.0 7.0 6.6 2.6 12.7 4.7 11.6 3.7 6.3 4.7 2.9 2.4 8.9 6.0 2.0 2.8 2.7 3.8 6.4 3.5 4.3 7.6 6.3 2.4 10.9 2.0 5.3 3.3 1.6 7.4 2.5 6.3 2.5 5.0 5.9 4.1 6.8 16.5 8.7 7.6 5.3 3.9 2.4 3.5 6.0 8.0 9.0 3.2 2.7 1.8 6.7 6.1 4.0 2.0 4.6 5.6 23.0 3.0 7.2 1.9 3.8 10.7 15.2 9.4 5.5 3.3 1.4 11.6 6.9 5.9 4.0 3.1 2.7 2.7 10.2 2.3 3.4 8.7 3.6 4.9 2.4 1.6 7.4 3.4 8.3 3.7 5.4 2.9 6.2 7.8 2.8 13.8 6.4 22.9 4.0 1.2 10.7 2.6 5.5 11.5 2.7 4.5 6.3 4.8 7.7 4.7 4.6 5.9 2.7 2.9 2.7 5.2 5.4 3.3 5.8 15.3 3.1 1.9 5.1 6.5 6.2 5.9 5.3 6.3 7.0 6.6 6.3 6.4 6.3 7.4 3.8 0.0 3.7 6.5 6.5 0.8 4.5 4.4 1.2 5.5 5.9 3.4 2.9 4.3 3.3 7.3 2.1 6.2 4.3 2.3 5.9 5.8 62.8 2.7 6.9 4.2 1.8 2.7 2.3 9.5 5.5 6.5 5.6 7.3 13.4 3.2 4.6 5.1 6.1 13.5 2.9 4.0 0.0 2.9 3.5 52.0 3.4 4.6 7.2 1.9 2.8 11.8 5.2 3.5 4.5 7.6 1.4 9.8 15.0 8.9 1.9 2.4 4.4 7.8 13.1 4.2 4.7 9.6 9.3 1.7 3.3 31.1 4.7 5.0 2.5 4.8 FJX1 "FLJ22416, FLJ25593" ENSG00000179431 "Four-jointed box kinase 1" Q86VR8 11 35618460-35620865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 29.0;Cytotrophoblasts: 25.6;Endometrial ciliated cells: 30.6;Endometrial stromal cells: 35.4;Granulosa cells: 31.2" "Cancer enhanced" "Detected in all" "glioma: 34.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-251 MG: 60.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059220 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA059220: AB_2683950" "unprognostic (8.99e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-3)" "unprognostic (5.20e-2)" "unprognostic (5.72e-2)" "unprognostic (9.56e-3)" "unprognostic (5.16e-2)" "unprognostic (1.06e-2)" "unprognostic (1.74e-1)" "unprognostic (4.39e-3)" "unprognostic (5.28e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (9.24e-9)" "unprognostic (1.64e-2)" "unprognostic (9.64e-2)" "unprognostic (8.35e-2)" "prognostic unfavorable (6.56e-4)" 8.9 5.9 8.4 1.7 10.4 0.1 3.5 6.8 9.2 7.8 4.4 2.1 0.3 5.2 1.5 3.8 4.9 2.3 2.5 10.2 7.1 9.5 2.2 2.8 1.1 8.2 13.1 9.2 3.5 0.6 2.3 3.4 6.6 5.2 0.2 0.7 2.5 2.2 1.1 6.0 1.3 1.6 9.6 5.0 1.6 0.7 12.0 1.0 2.9 0.3 1.7 3.8 3.3 10.1 23.3 11.4 12.0 3.8 4.1 12.6 3.7 25.4 17.3 24.1 17.2 14.5 7.1 0.0 5.7 10.2 49.6 24.3 4.2 42.6 20.4 0.3 33.0 2.1 4.4 0.6 9.7 2.7 0.1 4.8 31.8 12.7 38.1 3.9 11.1 1.2 12.5 0.1 23.6 5.4 0.8 0.0 16.4 0.1 33.6 1.4 26.6 5.4 18.6 28.5 11.2 6.4 2.7 2.1 7.5 8.7 48.2 0.5 21.7 19.0 35.5 3.7 60.9 0.0 0.0 0.0 33.9 1.1 28.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 10.4 6.8 9.2 10.2 7.1 8.2 13.1 6.6 9.6 12.0 10.1 7.8 0.0 0.0 9.4 0.2 17.5 15.8 14.0 29.0 1.8 5.3 13.3 1.2 0.0 3.9 0.0 12.5 25.6 0.0 0.1 1.9 7.6 0.3 30.6 35.4 11.8 0.0 0.0 6.6 0.2 13.9 7.2 0.0 6.5 0.0 31.2 17.9 0.4 3.6 0.0 3.9 0.0 2.0 0.6 1.7 0.1 0.6 1.1 0.0 1.0 0.0 12.5 0.0 6.6 1.7 1.4 0.0 0.7 0.0 22.9 0.0 8.0 4.3 0.5 0.0 6.0 22.3 0.6 1.0 5.6 9.5 11.9 0.4 3.1 0.0 2.5 FKBP10 "FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FKBP prolyl isomerase 10" Q96AY3 17 41812680-41823213 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 79.1;Fibroblasts: 100.0;Sertoli cells: 59.2;Smooth muscle cells: 65.3;Theca cells: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 551.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" 39.4 39.5 20.9 27.1 22.2 0.5 33.5 21.7 26.1 64.0 22.0 29.1 7.6 61.5 16.9 13.9 50.9 46.0 45.6 20.3 22.1 17.7 7.8 37.8 10.9 24.6 21.6 58.4 15.1 48.5 56.7 60.7 22.2 32.6 10.8 6.0 14.7 30.8 7.6 20.4 19.1 55.6 21.9 14.3 18.5 9.0 24.2 4.9 34.9 9.3 4.4 42.2 39.1 21.6 0.7 119.6 110.7 363.3 379.3 441.7 92.0 490.4 497.4 185.6 159.0 62.1 4.8 0.3 6.6 551.9 45.9 0.8 66.7 133.4 77.9 33.0 99.9 48.6 132.1 181.0 411.4 0.0 0.6 476.1 0.5 150.3 115.5 352.6 158.8 0.0 1.9 16.7 157.0 163.2 0.3 0.1 85.4 258.0 38.3 9.9 125.2 15.7 31.7 0.1 26.7 92.1 0.7 349.3 166.0 137.4 54.1 3.1 181.0 219.0 111.5 145.8 76.0 0.8 0.2 0.3 299.7 0.0 213.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.9 22.2 21.7 26.1 20.3 22.1 24.6 21.6 22.2 21.9 24.2 21.6 14.9 0.0 4.8 38.2 0.2 8.5 11.5 2.7 1.2 0.6 10.8 13.2 2.3 1.5 1.4 0.0 0.0 6.1 0.2 0.1 0.0 8.7 0.7 3.0 79.1 34.9 0.0 0.0 0.3 4.7 30.8 100.0 1.5 4.6 0.0 32.9 30.4 0.0 4.7 15.2 0.3 1.3 0.0 0.0 9.7 2.9 46.9 1.5 16.0 15.0 0.0 32.0 0.0 17.1 0.1 2.2 0.1 44.8 0.5 8.2 0.0 0.0 0.1 1.1 59.2 35.2 65.3 0.9 7.6 0.5 5.1 11.9 2.1 54.0 0.6 1.6 FKBP11 FKBP19 ENSG00000134285 "FKBP prolyl isomerase 11" Q9NYL4 12 48921518-48926474 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 495.0" "Cell type enriched" "Detected in many" 4 "Plasma cells: 1153.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 188.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 332.6;Karpas-707: 315.1;OE19: 527.2" "Low region specificity" "Detected in all" HPA041709 Enhanced Approved Centrosome NA NA 170000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Centrosome "HPA041709: AB_10794487" "unprognostic (7.45e-3)" "unprognostic (8.62e-2)" "unprognostic (2.40e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (3.46e-2)" "unprognostic (1.75e-1)" "unprognostic (7.64e-2)" "unprognostic (3.49e-3)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.15e-1)" "unprognostic (4.51e-1)" "unprognostic (2.79e-1)" "unprognostic (1.54e-1)" 25.6 17.6 4.0 60.2 4.1 34.5 34.5 3.7 4.9 42.4 5.6 57.2 70.8 17.4 86.4 16.2 19.1 25.4 13.1 3.8 12.0 13.8 59.4 23.9 55.4 5.7 6.3 13.8 495.0 4.7 47.2 15.6 5.2 28.9 53.3 2.1 160.2 32.7 2.4 8.0 55.9 26.2 3.8 76.4 70.6 6.1 9.6 16.4 22.9 0.4 77.4 49.2 17.3 4.8 13.6 24.7 3.0 4.5 116.0 141.3 3.8 123.2 183.3 128.0 154.5 78.3 88.3 192.8 2.2 226.8 1.1 60.6 31.6 60.4 77.0 39.1 7.7 6.6 24.7 0.3 332.6 3.2 3.3 165.0 109.8 99.2 171.4 67.2 75.4 53.1 3.0 315.1 49.9 44.7 26.3 5.1 7.4 527.2 33.9 76.5 3.3 280.7 21.0 2.3 35.0 10.6 36.6 66.5 24.4 4.0 2.0 7.0 49.2 21.0 2.8 2.1 2.3 132.3 122.2 108.1 16.1 3.9 33.0 6.0 1.0 2.8 115.7 1.3 188.3 50.5 80.5 92.7 1.9 25.7 38.8 69.9 4.1 26.7 1.1 39.3 33.4 36.3 4.0 4.1 3.7 4.9 3.8 12.0 5.7 6.3 5.2 3.8 9.6 4.8 22.3 16.0 19.1 5.2 229.8 28.3 56.0 48.6 39.3 5.5 45.0 43.3 2.3 30.0 42.8 9.2 39.6 21.5 130.9 23.1 7.9 23.7 18.4 19.2 117.8 32.3 25.1 20.6 5.3 171.7 80.7 64.1 31.6 31.0 12.7 34.0 40.4 96.6 10.9 1.7 3.7 227.7 16.2 15.1 26.1 17.4 27.7 10.1 272.1 0.0 8.0 1.8 158.6 1.5 1.8 59.8 14.3 13.9 1153.9 111.8 14.1 18.0 43.3 14.6 6.6 10.8 88.7 12.0 9.8 23.0 21.3 42.3 145.3 37.5 49.7 45.0 FKBP14 "FKBP22, FLJ20731" ENSG00000106080 "FKBP prolyl isomerase 14" Q9NWM8 7 30010587-30026702 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Deafness, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013329, HPA026829" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" Cytosol "Nucleoplasm, Golgi apparatus" "HPA013329: AB_1848613, HPA026829: AB_10601651" "prognostic unfavorable (1.60e-4)" "unprognostic (1.12e-3)" "unprognostic (6.84e-2)" "unprognostic (1.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (6.06e-2)" "unprognostic (7.00e-2)" "unprognostic (6.99e-2)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-3)" "prognostic unfavorable (4.25e-4)" 6.5 5.1 3.4 7.0 3.5 4.3 6.4 5.4 3.6 9.9 3.1 4.7 3.0 8.5 10.0 4.7 4.3 6.0 6.8 3.2 3.2 3.1 3.2 4.1 3.1 3.3 3.1 5.4 5.8 6.2 7.7 7.9 3.0 6.8 4.8 7.2 4.3 7.5 2.1 4.7 2.9 13.9 3.0 2.7 4.0 2.2 3.5 1.8 3.3 3.2 3.2 8.9 3.8 3.5 7.0 5.2 14.4 33.6 36.8 46.8 6.5 34.9 32.7 12.0 23.3 4.4 4.3 2.4 16.0 31.0 14.7 14.8 8.1 12.8 23.9 1.3 11.6 5.6 9.2 13.1 18.6 4.0 9.3 29.4 13.1 20.9 24.6 28.2 27.0 3.6 9.2 5.0 21.8 2.9 2.1 4.9 7.5 7.7 9.2 0.1 9.6 8.2 11.8 6.1 3.8 12.5 12.2 27.5 8.8 17.0 6.2 5.3 21.7 12.6 14.6 21.8 14.0 7.6 8.3 4.2 18.0 3.8 40.2 0.5 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.4 0.2 0.0 0.6 0.2 0.1 3.4 3.5 5.4 3.6 3.2 3.2 3.3 3.1 3.0 3.0 3.5 3.5 13.5 19.2 16.0 7.2 7.9 27.4 22.0 15.8 35.9 16.3 13.3 13.0 15.7 5.7 11.7 18.4 27.1 11.6 9.4 5.3 1.9 7.4 0.4 30.4 44.3 12.9 1.2 6.5 19.4 3.7 27.3 40.0 15.3 40.0 2.5 9.1 8.6 6.5 6.0 15.2 12.7 9.7 8.2 2.5 11.2 0.4 13.1 5.7 10.6 10.3 3.6 26.5 2.1 11.6 16.6 5.7 19.0 20.7 43.8 17.8 3.3 2.7 6.0 21.4 6.6 13.8 20.4 1.4 3.4 27.5 18.3 15.7 6.0 20.8 6.1 28.0 FKBP2 "FKBP-13, FKBP13, PPIase" ENSG00000173486 "FKBP prolyl isomerase 2" P26885 11 64241003-64244132 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 929.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025561, HPA049405" Enhanced Approved "Plasma membrane" "Intracellular and membrane" No No 510000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "CAB025561: , HPA049405: AB_2680749" "unprognostic (4.94e-2)" "unprognostic (1.12e-1)" "unprognostic (5.77e-2)" "unprognostic (2.66e-3)" "unprognostic (7.40e-2)" "unprognostic (1.92e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-1)" "unprognostic (3.23e-1)" "unprognostic (5.91e-3)" "unprognostic (5.86e-2)" "unprognostic (7.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (5.23e-1)" "unprognostic (2.30e-1)" "unprognostic (3.57e-2)" 64.7 127.6 185.1 77.5 187.6 50.1 58.3 192.7 234.7 113.1 210.8 105.7 136.3 81.1 397.7 68.4 94.4 77.2 117.4 185.0 196.9 122.7 197.3 62.7 70.7 199.9 199.6 75.3 280.1 160.4 200.9 73.1 197.7 92.5 84.2 37.1 208.9 146.7 33.3 60.9 107.3 72.6 183.4 67.5 113.4 74.7 194.3 59.0 187.6 48.4 70.4 85.7 61.6 196.0 101.2 144.8 82.8 165.9 178.5 98.2 94.6 132.9 146.4 108.8 101.4 148.1 257.0 80.8 195.4 186.5 148.2 134.7 70.5 121.0 51.3 101.4 54.5 90.0 196.5 158.3 231.6 74.5 125.5 116.0 169.3 145.4 163.5 156.9 86.9 76.6 61.0 253.6 138.1 186.7 85.1 112.6 92.6 211.1 130.0 70.8 70.9 299.2 198.9 120.7 110.0 91.3 85.4 263.2 147.9 59.5 98.1 69.5 68.9 123.8 100.9 182.8 72.6 128.5 48.6 69.0 156.7 80.6 142.8 276.8 173.1 25.9 178.9 191.2 230.8 170.1 139.2 176.4 172.2 165.0 90.4 131.5 68.6 162.9 162.7 929.1 55.9 126.7 185.1 187.6 192.7 234.7 185.0 196.9 199.9 199.6 197.7 183.4 194.3 196.0 129.5 147.4 168.0 20.9 179.7 164.4 251.0 447.2 125.2 86.4 205.0 185.4 134.7 275.9 270.6 389.9 22.9 279.8 174.4 534.1 412.8 270.8 126.4 212.5 206.3 138.6 342.6 41.4 11.3 254.2 386.9 167.0 179.4 258.5 144.0 146.5 148.5 754.4 228.4 32.0 14.8 508.2 305.2 100.1 201.7 99.0 230.2 140.7 300.6 16.9 151.7 181.7 111.2 11.1 20.6 292.2 424.7 255.1 765.2 315.5 594.7 792.2 241.9 83.3 184.1 138.4 221.3 327.1 282.1 136.6 168.1 620.5 123.6 138.8 339.4 312.0 FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 149.1;Endometrial stromal cells: 54.8;Fibroblasts: 67.6;Leydig cells: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 155.0;ASC TERT1: 96.7;fHDF/TERT166: 60.9;HSkMC: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.3 5.4 1.5 3.9 1.6 1.4 11.9 2.6 2.8 23.1 1.5 8.3 2.8 27.8 11.3 5.9 15.1 15.4 12.3 1.6 1.8 5.2 8.3 7.8 2.9 1.6 1.5 50.0 2.8 2.7 5.0 13.0 1.5 9.3 6.2 2.1 5.0 13.3 3.8 4.2 4.4 19.2 1.2 3.0 5.4 4.4 1.5 2.5 6.6 6.5 2.8 11.6 10.2 2.1 0.2 1.9 18.5 27.8 155.0 96.7 1.7 33.3 55.0 5.9 19.0 0.3 1.9 5.4 7.3 60.9 5.5 0.3 7.1 2.8 10.3 4.5 3.9 5.7 7.3 5.5 23.7 3.5 3.8 64.7 1.4 24.0 3.4 44.2 19.8 6.6 2.5 3.4 25.2 0.3 6.1 6.0 3.6 3.5 2.9 7.8 31.9 7.7 8.4 0.6 9.7 32.0 7.0 0.2 6.2 12.7 0.5 6.8 18.2 11.0 6.8 12.8 3.2 6.3 7.2 2.6 19.9 8.7 24.3 0.0 0.4 0.0 1.0 0.7 1.2 1.1 0.9 0.7 2.6 0.7 0.9 1.0 0.0 0.6 0.0 2.1 1.1 0.4 1.5 1.6 2.6 2.8 1.6 1.8 1.6 1.5 1.5 1.2 1.5 2.1 16.2 6.4 4.1 2.9 5.4 7.0 9.3 19.6 7.4 4.2 6.7 13.6 16.1 2.8 5.2 7.3 0.0 7.6 2.7 0.7 1.9 10.9 149.1 3.4 54.8 19.3 1.2 4.2 1.6 8.4 22.4 67.6 4.1 3.5 14.0 19.0 15.7 11.9 5.8 5.0 3.7 5.6 14.2 4.4 13.6 27.1 64.0 3.8 17.8 4.7 1.6 4.2 1.0 7.1 4.2 3.9 0.7 48.5 10.3 3.4 0.4 3.7 2.1 3.6 6.6 31.1 37.7 8.5 5.1 3.7 5.8 5.1 5.5 30.4 3.1 4.1 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FKRP "FKTR, LGMD2I, MDC1C" ENSG00000181027 "Fukutin related protein" Q9H9S5 19 46746046-46776988 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transferase "Cardiomyopathy, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043115, HPA060454" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA043115: AB_2678324, HPA060454: AB_2684281" "unprognostic (4.44e-2)" "unprognostic (5.20e-2)" "unprognostic (2.19e-2)" "unprognostic (8.37e-3)" "unprognostic (1.83e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "unprognostic (2.99e-2)" "unprognostic (4.59e-3)" "prognostic favorable (8.98e-4)" "unprognostic (3.53e-1)" "unprognostic (2.30e-2)" "unprognostic (2.53e-1)" "unprognostic (2.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.53e-2)" 10.5 9.1 8.5 8.1 8.2 8.8 9.9 3.7 11.5 11.4 4.5 13.3 4.8 15.2 5.0 8.8 12.6 6.0 15.8 8.5 10.4 12.0 11.9 10.4 7.4 10.1 7.3 12.7 11.1 7.5 16.8 10.1 8.8 13.5 4.3 5.7 11.1 7.4 19.6 7.2 10.5 5.8 6.1 14.7 10.9 9.3 9.4 5.6 13.6 9.8 4.9 13.0 10.5 8.7 12.7 26.5 17.8 12.5 15.4 16.9 15.8 31.7 21.0 12.6 19.9 17.0 21.4 11.7 17.0 18.2 20.9 13.0 6.6 14.8 11.5 21.9 22.2 11.7 14.4 10.7 13.3 9.3 19.8 19.4 12.5 15.6 15.2 14.6 16.7 6.0 12.2 11.0 12.7 5.8 6.8 22.8 17.2 7.8 6.5 18.3 11.1 4.0 8.0 26.4 12.0 23.1 15.8 7.6 10.6 11.7 8.9 7.3 16.8 18.4 19.8 6.7 25.7 11.6 15.4 11.0 15.0 7.5 25.6 1.3 1.8 0.8 1.5 1.0 0.9 1.7 1.1 1.7 1.1 2.4 1.2 1.6 2.2 2.0 1.1 1.9 0.6 1.2 8.5 8.2 3.7 11.5 8.5 10.4 10.1 7.3 8.8 6.1 9.4 8.7 4.7 9.6 7.4 6.8 3.9 0.8 4.8 3.0 1.2 9.8 5.3 5.2 15.5 4.3 5.6 5.5 6.2 9.6 9.1 4.5 5.9 4.2 12.0 7.9 7.3 6.0 7.8 7.8 6.8 2.4 5.9 6.6 3.6 5.1 1.3 6.7 11.4 16.6 7.6 3.3 8.2 4.2 2.0 10.0 1.2 13.2 5.6 4.3 5.4 3.7 6.1 7.8 2.1 8.0 6.2 4.1 4.7 4.1 3.6 4.3 4.2 8.2 9.7 11.0 6.6 7.2 7.0 12.2 4.0 2.4 1.6 18.7 4.3 4.5 4.0 4.3 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FMN1 "DKFZP686C2281, FLJ45135, FMN, LD, MGC125288, MGC125289" ENSG00000248905 "Formin 1" Q68DA7 15 32765544-33194714 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;retina: 30.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 117.0;Cone photoreceptor cells: 221.0;Excitatory neurons: 439.4;Inhibitory neurons: 340.0" "Cancer enriched" "Detected in many" 9 "melanoma: 14.5" "Region enriched" "Detected in some" 7 "cerebral cortex: 16.9" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 21.4;RH-30: 26.9;SK-MEL-30: 28.7;T-47d: 24.8;U-138 MG: 17.2;U-2197: 17.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005465, HPA046786" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA005465: AB_1859515, HPA046786: AB_10963545" "unprognostic (1.57e-1)" "unprognostic (5.92e-3)" "unprognostic (1.96e-1)" "unprognostic (2.10e-3)" "unprognostic (3.67e-2)" "unprognostic (3.00e-2)" "unprognostic (1.56e-2)" "unprognostic (2.84e-2)" "unprognostic (3.44e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-3)" "unprognostic (3.53e-1)" "unprognostic (4.89e-2)" "unprognostic (2.89e-2)" "unprognostic (3.73e-1)" "unprognostic (4.32e-1)" "unprognostic (7.61e-2)" 1.8 0.8 0.0 2.4 0.0 1.2 3.0 0.0 16.9 5.3 0.0 5.7 1.3 1.0 0.7 2.0 3.1 2.4 0.9 0.0 0.0 2.8 0.5 3.4 0.9 2.3 0.0 0.2 1.2 1.4 3.7 3.7 0.0 1.8 4.4 30.0 4.2 1.2 0.7 4.2 1.8 2.2 0.0 1.0 7.9 10.2 1.7 3.8 2.5 0.5 0.6 1.3 3.6 0.0 3.8 4.0 0.8 0.4 0.1 0.4 4.9 5.4 4.1 1.5 4.0 0.6 5.0 0.6 1.8 6.1 3.4 3.7 0.1 3.7 3.9 0.0 0.2 3.1 0.8 0.4 0.2 0.0 0.2 1.5 0.2 7.9 0.1 3.1 0.0 0.1 0.0 21.4 8.8 3.9 0.1 0.0 1.1 7.0 0.3 0.6 26.9 4.9 1.8 1.5 0.3 0.9 0.0 3.3 28.7 0.9 24.8 0.0 4.9 17.2 2.7 17.9 1.6 0.0 0.0 0.9 7.3 0.2 10.1 1.3 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.2 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 2.3 0.0 0.0 0.0 1.7 0.0 0.4 41.7 46.9 10.1 1.6 3.7 3.2 2.0 3.4 117.0 7.7 5.1 3.1 14.3 17.3 0.0 221.0 12.0 5.4 13.3 11.7 5.7 16.5 17.4 2.4 2.7 9.0 0.4 439.4 1.8 5.9 2.6 97.9 7.0 24.0 1.8 0.0 0.4 10.9 47.1 340.0 16.8 16.2 28.0 3.9 12.8 0.9 29.6 33.8 64.6 5.8 6.9 0.0 8.0 61.9 11.4 11.4 0.7 2.2 4.5 4.0 1.6 29.4 102.4 0.0 13.0 1.0 18.4 16.0 7.3 3.4 18.3 5.0 0.1 9.9 5.7 FMO2 ENSG00000094963 "Flavin containing dimethylaniline monoxygenase 2" Q99518 1 171185249-171212686 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 69.7;lung: 93.9" "Cell type enhanced" "Detected in many" "Adipocytes: 187.0;Alveolar cells type 1: 461.6;Club cells: 204.7;Fibroblasts: 98.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 57 "ASC diff: 30.6;ASC TERT1: 13.7;HSkMC: 37.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028261 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA028261: AB_10601012" "unprognostic (1.85e-2)" "unprognostic (3.14e-2)" "unprognostic (7.44e-2)" "unprognostic (3.75e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-2)" "unprognostic (1.66e-3)" "unprognostic (3.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.58e-2)" "unprognostic (1.16e-1)" "unprognostic (4.28e-1)" "unprognostic (1.53e-1)" "unprognostic (1.26e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (3.83e-2)" 69.7 24.0 1.5 1.3 2.4 0.1 47.8 1.3 1.4 6.6 2.9 6.5 0.9 5.1 7.7 65.9 33.3 4.6 50.0 0.8 4.1 10.4 4.3 93.9 11.6 2.2 1.7 4.3 5.5 4.9 6.3 0.3 1.7 5.5 1.7 0.9 36.5 2.9 17.6 4.5 4.2 3.9 1.5 0.7 6.8 1.1 4.7 8.6 12.0 20.3 11.8 4.5 11.6 1.1 0.0 0.0 0.0 0.0 30.6 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 37.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.4 1.3 1.4 0.8 4.1 2.2 1.7 1.7 1.5 4.7 1.1 187.0 461.6 21.7 2.6 0.1 0.4 4.4 36.0 2.8 0.4 14.5 69.1 9.2 0.0 204.7 1.8 0.0 0.0 0.5 0.0 0.0 0.5 5.5 0.1 0.1 69.1 0.0 0.0 0.1 0.0 0.0 98.7 0.0 0.0 3.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.7 2.8 0.9 1.8 0.0 37.5 0.0 0.2 0.0 2.0 0.1 1.3 0.0 0.0 2.5 3.7 0.0 10.2 36.0 0.6 0.0 9.7 48.5 0.3 0.1 7.4 0.0 0.0 1.1 1.6 0.0 1.2 FMO3 FMOII ENSG00000007933 "Flavin containing dimethylaniline monoxygenase 3" P31513 1 171090901-171117819 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1123.3" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 412.3" "Cancer enriched" "Detected in many" 13 "liver cancer: 94.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 34.6;ASC TERT1: 26.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA013750 Enhanced NA NA "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA013750: AB_1848968" "unprognostic (1.87e-2)" "unprognostic (6.30e-2)" "unprognostic (1.00e-1)" "unprognostic (6.81e-3)" "unprognostic (2.64e-1)" "unprognostic (1.31e-3)" "prognostic favorable (3.46e-4)" "prognostic favorable (5.60e-5)" "unprognostic (2.95e-1)" "unprognostic (9.34e-2)" "unprognostic (3.02e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (3.45e-1)" "unprognostic (7.27e-2)" 27.2 12.4 2.5 0.9 2.7 0.4 6.8 2.5 3.6 1.2 2.3 1.4 1.8 1.3 3.0 5.1 13.3 1.8 4.2 2.3 2.6 14.0 1123.3 18.7 4.9 5.0 2.7 0.3 4.5 4.2 4.3 0.2 3.1 1.1 0.7 0.1 5.1 0.4 4.6 4.3 2.2 1.6 4.0 0.4 3.9 0.5 2.8 1.4 2.6 3.1 9.1 1.0 0.9 2.6 0.0 0.0 0.0 0.0 34.6 26.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.0 7.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.7 2.5 3.6 2.3 2.6 5.0 2.7 3.1 4.0 2.8 2.6 2.7 12.8 0.5 0.0 0.7 0.4 0.4 2.7 0.0 0.0 0.1 0.3 0.4 7.2 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.2 0.0 4.7 0.0 29.5 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 6.8 412.3 0.0 0.0 0.0 0.0 4.1 9.5 0.8 0.0 0.3 0.1 1.8 1.0 0.0 0.5 0.0 7.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 22.7 0.2 6.6 1.3 6.3 0.4 0.1 0.4 0.4 0.0 0.8 0.2 0.0 0.1 FMO5 ENSG00000131781 "Flavin containing dimethylaniline monoxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 683.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 64.2;Cholangiocytes: 133.0;Hepatocytes: 265.4;Proximal enterocytes: 108.8;Proximal tubular cells: 69.2" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "Hep G2: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favorable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" 3.1 5.7 2.0 5.1 2.9 2.0 46.1 3.9 2.8 7.8 0.5 41.3 71.3 2.8 6.9 1.2 3.6 15.8 3.1 2.1 2.4 51.5 683.3 27.1 4.0 4.2 2.9 4.1 48.1 68.3 6.7 2.4 4.8 9.7 46.6 0.9 32.7 4.0 0.8 11.6 73.9 3.5 3.2 4.0 120.1 5.2 3.1 1.1 2.0 1.4 2.5 3.9 1.5 5.6 0.1 1.1 0.6 0.1 2.8 0.8 0.9 0.7 0.5 0.3 0.8 0.7 2.4 0.4 0.8 0.8 0.2 0.4 0.0 0.0 0.0 1.4 0.2 1.6 0.1 41.7 0.9 1.4 9.0 1.3 0.2 0.4 0.0 0.4 0.6 0.2 0.1 0.1 1.5 1.4 0.2 0.7 2.8 5.3 0.8 0.4 0.5 0.4 3.4 0.6 0.5 0.3 0.9 2.8 1.3 1.3 2.1 10.4 1.1 0.0 0.3 0.9 0.0 0.3 0.0 0.3 1.1 0.5 0.3 7.0 12.9 4.1 2.0 5.9 0.3 4.7 0.5 0.6 5.4 8.5 0.3 1.3 1.3 1.2 1.8 2.5 1.6 3.9 2.0 2.9 3.9 2.8 2.1 2.4 4.2 2.9 4.8 3.2 3.1 5.6 2.8 9.6 64.2 11.1 6.4 1.7 3.9 0.9 1.8 2.0 17.5 6.7 1.9 133.0 10.4 14.7 0.0 1.5 1.7 60.8 7.9 7.5 7.7 2.5 1.8 2.7 6.7 4.8 8.2 5.9 1.1 2.9 24.5 6.1 5.7 9.8 5.0 265.4 4.0 3.3 6.4 34.4 4.1 10.0 2.3 4.5 2.8 4.6 28.4 10.3 5.3 0.2 4.1 10.1 17.5 7.0 29.0 1.5 0.4 5.6 108.8 69.2 18.1 1.3 0.0 2.2 1.0 5.9 0.9 1.3 1.6 1.4 2.6 6.6 20.7 6.4 FMOD SLRR2E ENSG00000122176 Fibromodulin Q06828 1 203340628-203351758 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 26.7;Fibroblasts: 52.5;Intestinal goblet cells: 80.2;Leydig cells: 28.0;Peritubular cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.6;CACO-2: 38.6;HHSteC: 11.8;HSkMC: 22.1;OE19: 45.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 71.7" "Secreted to extracellular matrix" NA NA 2600000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: OE19 - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.48e-1)" "unprognostic (8.88e-2)" "unprognostic (9.35e-2)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "unprognostic (4.17e-3)" "unprognostic (1.86e-1)" "unprognostic (3.30e-1)" "unprognostic (5.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (9.40e-3)" "unprognostic (3.58e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (2.67e-4)" 122.7 13.6 1.3 31.1 2.3 0.1 64.4 1.5 3.9 100.1 9.0 39.4 49.6 105.8 17.2 19.1 85.8 123.6 149.0 1.0 1.5 24.3 11.0 60.2 28.6 2.4 0.9 125.1 33.1 28.0 21.7 81.2 1.5 58.4 62.1 9.9 49.6 49.2 12.6 25.9 21.2 106.5 2.1 18.2 135.6 6.3 1.5 9.6 71.3 25.6 33.8 45.4 60.0 1.4 0.0 0.1 0.0 0.0 10.6 0.7 0.2 7.1 8.1 0.0 1.1 38.6 0.0 0.0 0.8 7.7 0.0 0.3 0.0 0.6 0.5 0.0 0.0 0.0 0.9 0.0 11.8 0.0 0.0 22.1 0.1 0.0 0.4 5.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.3 0.0 45.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 1.0 0.3 2.0 0.0 0.3 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.3 1.5 3.9 1.0 1.5 2.4 0.9 1.5 2.1 1.5 1.4 9.3 0.0 6.3 0.0 0.0 6.9 5.0 1.5 6.2 0.2 10.3 26.7 1.6 2.8 2.1 7.3 0.0 1.1 0.4 2.9 0.0 1.9 0.1 1.1 12.1 8.3 6.1 0.0 0.1 0.7 0.7 52.5 12.8 1.6 0.0 0.5 19.2 0.1 1.2 0.0 0.0 80.2 0.0 0.3 9.3 0.4 28.0 0.6 12.4 7.5 0.6 11.9 0.0 0.0 0.0 1.5 2.2 28.6 0.0 11.7 0.7 0.2 0.7 1.0 6.6 1.3 15.5 0.0 0.3 0.6 4.3 3.1 1.2 2.0 8.6 1.6 FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2583.6;Fibroblasts: 562.6;Hepatocytes: 1012.4;Smooth muscle cells: 450.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 34405.9;HSkMC: 16044.5;hTERT-HME1: 9585.3;hTERT-RPE1: 10587.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" 151.1 31.4 37.8 131.9 44.8 0.6 76.5 36.3 51.2 135.9 85.9 444.0 33.8 156.1 61.3 251.6 174.5 187.1 410.9 38.9 41.1 42.9 1725.9 785.7 37.3 37.7 39.8 110.0 26.0 19.3 26.2 2928.1 43.5 105.6 237.2 6.0 67.0 428.9 37.7 52.7 103.4 722.6 36.2 14.3 127.2 25.8 112.1 133.8 40.4 148.4 23.9 361.7 87.1 35.3 12.5 84.2 104.6 22.8 4456.5 34405.9 4.8 1799.2 1200.2 1765.3 1259.9 1059.2 43.7 1.2 9.7 6331.7 47.2 192.7 17.4 4220.9 946.9 1.0 7.4 0.8 24.7 3607.2 3192.2 1.2 6.6 16044.5 29.3 4136.5 9585.3 10587.1 2177.2 1.0 8.2 5.0 3673.9 17.0 2.9 1.5 52.7 2.4 15.2 1.0 2.4 8.0 47.4 13.7 6.0 25.0 213.7 116.4 1219.8 4649.5 19.4 3.2 4161.0 2553.1 269.9 2837.4 355.6 4.4 1.6 1.6 3161.2 1.0 694.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.8 44.8 36.3 51.2 38.9 41.1 37.7 39.8 43.5 36.2 112.1 35.3 138.9 67.3 67.8 13.4 2.3 55.1 4.1 227.0 2.2 6.4 4.2 5.2 36.3 30.0 34.0 16.5 0.0 216.6 2.3 3.4 0.0 6.5 1.8 6.5 265.8 215.4 21.0 16.8 9.5 9.8 2583.6 562.6 4.1 5.5 18.9 53.5 227.7 1012.4 365.2 1.7 8.1 10.2 12.2 38.0 73.7 4.6 186.4 85.9 110.3 101.2 1.2 1.9 0.0 11.6 10.7 12.5 1.4 88.4 1.7 17.8 0.0 0.6 23.1 8.7 72.3 401.5 450.2 1.6 7.8 5.0 37.4 205.8 11.3 8.5 23.7 1.7 FNDC1 "bA243O10.1, dJ322A24.1, FNDC2, KIAA1866" ENSG00000164694 "Fibronectin type III domain containing 1" Q4ZHG4 6 159169400-159272108 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 14.2;thyroid gland: 20.3" "Group enriched" "Detected in some" 4 "Fibroblasts: 28.7;Smooth muscle cells: 11.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.5" "Group enriched" "Detected in many" 6 "cerebral cortex: 5.4;hippocampal formation: 8.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;fHDF/TERT166: 2.9;SuSa: 3.1" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA030962, HPA030963" Approved Approved "Nuclear speckles" "Secreted to extracellular matrix" NA NA 14000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA030962: AB_10696212, HPA030963: AB_2673676" "unprognostic (4.59e-2)" "unprognostic (9.17e-3)" "unprognostic (7.62e-2)" "prognostic favorable (6.10e-5)" "unprognostic (4.57e-1)" "unprognostic (2.11e-1)" "unprognostic (5.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "unprognostic (4.18e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.93e-6)" "unprognostic (6.49e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.76e-3)" 5.4 0.5 0.5 1.9 0.3 0.0 2.1 0.1 5.4 6.5 0.2 12.9 2.5 2.2 0.0 1.1 0.6 14.2 3.9 8.7 0.3 0.6 0.7 1.6 2.8 0.1 1.0 1.2 1.1 0.3 0.2 0.9 0.0 0.4 1.8 0.1 0.9 0.8 2.1 0.9 4.2 11.7 0.3 0.5 0.4 0.4 0.4 0.1 20.3 9.6 2.4 1.0 1.6 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 5.4 8.7 0.3 0.1 1.0 0.0 0.3 0.4 1.2 2.6 0.0 0.6 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.1 0.5 2.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.3 0.4 4.7 0.7 0.0 0.0 0.2 0.0 0.2 28.7 0.0 0.3 0.0 0.1 1.4 0.0 0.2 0.0 1.7 0.0 0.0 0.0 3.1 0.0 0.3 0.2 1.8 2.8 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 3.0 11.5 1.1 1.4 0.0 1.4 0.1 0.5 0.1 0.0 0.0 FNDC7 FLJ35838 ENSG00000143107 "Fibronectin type III domain containing 7" Q5VTL7 1 108712908-108742749 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.3;testis: 1.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 4.6;Late spermatids: 1.5;Oligodendrocyte precursor cells: 3.5;Oligodendrocytes: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028079, HPA054297" Enhanced Approved "Nucleoplasm,Actin filaments" "Secreted in male reproductive system" NA NA "Cluster 77: Retina - Visual perception" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Actin filaments" Nucleoplasm "HPA028079: AB_10602501, HPA054297: AB_2682441" "unprognostic (2.35e-2)" "unprognostic (2.65e-2)" "unprognostic (3.74e-1)" "unprognostic (8.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-4)" "unprognostic (1.90e-10)" "unprognostic (1.59e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" 0.0 0.0 0.4 0.0 0.4 0.1 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.8 0.4 1.1 1.3 0.6 0.7 0.4 0.5 0.2 0.0 0.0 2.6 0.2 0.0 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 4.6 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.8 0.0 3.5 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 FNIP1 KIAA1961 ENSG00000217128 "Folliculin interacting protein 1" Q8TF40 5 131641714-131797063 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 398.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 16.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068099, HPA071213" Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA068099: AB_2685952, HPA071213: AB_2686362" "unprognostic (1.91e-3)" "unprognostic (2.47e-1)" "unprognostic (6.41e-3)" "unprognostic (2.49e-1)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "unprognostic (6.32e-2)" "unprognostic (1.25e-1)" "unprognostic (6.00e-2)" "unprognostic (1.37e-2)" "unprognostic (2.74e-1)" "unprognostic (5.52e-2)" "unprognostic (7.05e-2)" "unprognostic (2.92e-1)" "unprognostic (2.32e-1)" "unprognostic (3.13e-3)" "unprognostic (4.47e-1)" 10.1 8.4 8.2 6.6 16.5 15.9 8.8 9.9 13.2 8.7 4.8 7.0 8.1 9.2 6.9 6.1 7.2 8.1 8.9 9.0 8.6 7.5 12.1 8.4 6.2 10.3 11.0 12.9 6.7 12.8 5.6 7.6 12.4 8.2 6.4 7.1 6.5 5.2 13.2 8.2 7.0 7.4 9.8 7.0 7.4 13.8 10.2 5.7 10.4 14.2 6.1 7.3 6.8 30.2 10.8 9.2 6.7 19.1 23.1 16.2 11.7 12.1 21.4 13.9 22.5 11.9 10.7 8.5 7.9 14.6 43.0 8.8 7.9 9.9 19.7 11.9 5.7 21.3 9.7 7.4 15.6 4.1 39.7 18.7 12.8 15.4 25.9 11.6 6.7 9.9 9.3 19.1 17.3 3.5 8.5 10.8 4.0 3.2 4.3 7.2 14.2 5.5 8.3 18.1 6.8 7.4 10.7 5.8 17.6 11.1 11.1 14.6 12.2 23.4 10.7 20.5 10.7 17.9 17.8 8.4 19.3 11.3 13.3 7.2 3.0 3.9 2.0 3.4 2.2 3.5 2.1 1.9 1.8 2.7 2.2 2.6 16.6 2.7 3.1 1.8 2.2 1.3 8.2 16.5 9.9 13.2 9.0 8.6 10.3 11.0 12.4 9.8 10.2 30.2 36.1 6.4 26.9 108.7 55.2 36.7 68.3 9.0 33.6 46.3 53.7 28.8 31.2 41.5 11.9 11.0 98.0 26.1 55.3 26.2 3.9 34.5 11.6 33.7 43.9 37.8 31.3 38.3 142.3 26.4 36.5 49.7 56.1 41.9 24.6 30.7 41.7 32.1 49.3 45.4 153.1 18.6 16.2 70.6 44.0 9.1 60.9 72.3 44.4 105.9 57.9 35.6 46.4 126.7 398.7 29.6 32.7 44.4 29.6 71.2 80.1 17.8 9.3 54.6 6.6 58.3 35.7 84.8 43.9 22.9 31.1 69.2 41.7 32.9 26.5 72.3 FOCAD "FLJ20375, KIAA1797" ENSG00000188352 Focadhesin Q5VW36 9 20658309-20995955 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "choroid plexus: 154.6" "Cell type enhanced" "Detected in all" "Excitatory neurons: 529.1;Inhibitory neurons: 314.2;Oligodendrocyte precursor cells: 140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055015 Approved Uncertain Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA055015: AB_2682673" "unprognostic (3.05e-2)" "unprognostic (1.02e-1)" "prognostic favorable (3.25e-4)" "unprognostic (3.69e-3)" "unprognostic (4.14e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (9.64e-2)" "unprognostic (7.38e-2)" "unprognostic (1.23e-1)" "unprognostic (5.26e-2)" "unprognostic (9.15e-2)" "prognostic favorable (3.09e-8)" "unprognostic (1.90e-1)" "unprognostic (2.33e-1)" "unprognostic (3.99e-2)" "unprognostic (1.41e-2)" 7.3 19.4 15.0 6.1 14.7 5.2 7.7 12.7 21.9 8.5 154.6 9.5 4.5 9.0 11.2 8.9 13.2 5.2 12.5 23.0 20.6 9.5 4.9 8.6 5.3 10.7 8.1 7.4 12.8 12.3 25.1 8.3 10.5 10.5 10.4 7.1 11.9 7.1 11.2 8.5 6.4 9.0 5.2 6.2 8.2 7.7 15.8 14.5 20.4 11.8 6.2 7.3 7.7 17.5 32.8 22.2 23.7 17.8 21.7 24.7 12.5 19.1 30.2 13.3 15.1 14.8 11.0 13.4 9.9 27.4 11.1 11.2 20.8 37.8 23.0 59.8 15.4 10.5 25.3 18.5 11.2 17.5 13.0 22.9 25.5 13.2 21.6 18.5 51.3 11.1 0.3 19.2 22.3 12.6 13.3 33.0 18.7 17.4 22.2 0.1 10.7 9.0 20.6 13.9 15.7 7.9 12.6 21.3 5.2 31.5 13.3 10.2 31.7 0.1 8.7 14.7 17.5 4.7 28.3 15.0 0.0 24.3 8.0 6.8 1.6 4.9 2.9 3.3 3.8 1.5 2.5 2.8 4.0 2.6 2.2 2.7 1.2 2.7 1.9 1.6 2.6 1.7 15.0 14.7 12.7 21.9 23.0 20.6 10.7 8.1 10.5 5.2 15.8 17.5 7.0 9.6 14.7 85.8 5.2 2.9 2.8 4.5 6.8 5.8 5.8 5.1 14.9 4.3 8.6 16.5 4.2 4.7 4.1 7.9 1.9 8.1 16.6 21.2 6.7 6.0 17.5 5.5 529.1 8.6 7.6 8.7 12.8 6.8 5.1 13.9 9.7 4.0 5.1 11.8 314.2 10.1 10.2 4.4 3.5 5.0 5.0 5.3 8.8 74.9 2.8 7.9 2.1 140.8 59.0 8.9 3.4 3.8 10.7 5.8 2.5 4.8 25.0 4.0 6.6 11.2 6.7 13.7 7.5 11.2 3.7 3.3 5.7 7.0 10.4 3.0 FOLR2 FRβ ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 168.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 1114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.2;intermediate monocyte: 50.6" "Group enriched" "Detected in many" 4 "dendritic cells: 18.7;monocytes: 64.2" "Cell line enriched" "Detected in some" 5 "U-698: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 15000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.03e-1)" "unprognostic (6.58e-3)" "prognostic unfavorable (8.42e-4)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-1)" "unprognostic (3.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.98e-3)" 119.1 55.0 10.7 28.2 11.0 10.8 31.7 8.2 18.6 27.9 13.8 36.0 19.5 13.5 12.4 31.6 16.8 80.1 38.6 10.9 9.5 10.8 44.8 39.7 78.5 9.3 10.7 16.0 7.1 7.9 6.1 168.4 11.4 6.1 46.7 0.2 12.8 16.7 5.9 9.8 29.6 46.3 9.3 27.7 21.0 13.0 16.2 28.7 9.1 26.3 29.0 81.3 6.3 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.2 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 0.0 0.2 0.0 18.6 0.5 0.8 0.0 0.0 64.2 0.0 0.3 50.6 0.0 9.5 0.0 0.0 18.7 4.0 0.0 0.0 1.1 1.8 13.7 0.2 0.0 20.4 10.7 11.0 8.2 18.6 10.9 9.5 9.3 10.7 11.4 9.3 16.2 16.1 3.4 0.0 0.6 0.0 8.0 7.9 0.1 0.0 1.2 0.0 0.1 1.1 2.2 1.5 0.0 0.0 0.0 7.6 0.6 0.0 0.0 0.0 0.9 0.3 0.1 2.3 0.0 0.0 0.0 0.0 6.0 2.4 0.0 0.5 2.5 0.0 2.2 1.7 1114.8 0.0 0.0 0.0 0.0 229.3 98.8 2.5 1.5 199.4 0.0 15.9 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.1 0.1 0.0 0.2 0.0 0.3 0.0 2.5 1.2 0.6 0.7 1.3 5.1 16.0 1.2 0.1 0.0 0.1 FOLR3 "FR-G, FRγ" ENSG00000110203 "Folate receptor gamma" P41439 11 72114869-72139892 "Metabolic proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 98.7;lymphoid tissue: 28.4" "Group enriched" "Detected in some" 10 "Distal tubular cells: 406.9;monocytes: 103.0" "Cancer enhanced" "Detected in some" "ovarian cancer: 5.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "classical monocyte: 330.8;neutrophil: 492.8" "Group enriched" "Detected in many" 11 "granulocytes: 492.8;monocytes: 330.8" "Group enriched" "Detected in some" 5 "hTERT-HME1: 72.4;U-2197: 64.7" "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.47e-2)" "unprognostic (6.26e-3)" "unprognostic (1.94e-2)" "unprognostic (8.72e-3)" "unprognostic (6.87e-3)" "unprognostic (9.56e-2)" "unprognostic (1.58e-1)" "unprognostic (3.72e-1)" "unprognostic (1.72e-1)" "unprognostic (1.54e-1)" "unprognostic (7.35e-2)" "unprognostic (7.90e-2)" "unprognostic (8.39e-2)" "unprognostic (9.99e-4)" "unprognostic (1.96e-1)" "unprognostic (2.03e-6)" "unprognostic (4.17e-1)" 5.7 0.4 0.3 10.6 0.2 98.7 0.2 0.2 0.5 0.2 0.3 0.2 0.4 0.0 0.0 1.0 0.9 0.3 0.5 0.2 0.3 8.6 0.8 5.9 0.1 0.3 0.3 0.0 0.2 0.0 0.1 0.7 0.3 0.2 0.1 0.0 0.6 0.1 0.1 0.6 0.5 0.6 0.2 28.4 0.4 0.9 0.6 1.3 1.7 0.5 0.0 0.5 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.3 10.4 13.1 3.7 9.2 0.0 0.0 0.0 1.3 2.0 0.2 1.1 0.0 6.9 8.4 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 8.8 5.4 72.4 1.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.6 0.3 64.7 0.0 0.1 0.0 0.0 2.7 0.0 0.0 15.1 330.8 30.9 0.5 26.1 1.8 0.3 0.1 0.2 36.2 0.1 0.1 0.0 492.8 0.5 1.4 6.3 0.4 294.4 0.3 0.2 0.2 0.5 0.2 0.3 0.3 0.3 0.3 0.2 0.6 0.3 0.1 0.0 7.9 0.0 1.1 0.3 0.0 0.9 0.0 0.0 0.1 0.0 0.1 0.0 1.9 23.9 0.0 0.1 1.3 0.0 406.9 0.1 3.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 3.8 0.0 1.1 0.0 1.6 0.0 0.0 0.0 0.0 22.4 1.7 10.9 0.0 17.4 0.0 0.0 103.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 18.1 1.5 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 1.0 0.1 0.0 0.1 FOXK1 IMAGE:5164497 ENSG00000164916 "Forkhead box K1" P85037 7 4682295-4771442 "Predicted intracellular proteins, Transcription factors" "Differentiation, Host-virus interaction, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017998, HPA018864" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Nucleoli fibrillar center" "HPA017998: AB_1849077, HPA018864: AB_1849079" "unprognostic (3.05e-2)" "unprognostic (5.01e-2)" "unprognostic (1.54e-1)" "unprognostic (1.55e-2)" "unprognostic (3.51e-1)" "unprognostic (3.03e-1)" "prognostic unfavorable (2.54e-6)" "unprognostic (2.34e-2)" "unprognostic (2.62e-2)" "unprognostic (1.73e-3)" "unprognostic (2.66e-3)" "unprognostic (4.96e-2)" "unprognostic (3.79e-3)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (4.34e-2)" "unprognostic (3.72e-1)" 6.3 11.3 6.9 4.2 7.1 9.5 5.7 1.4 8.9 7.1 0.0 9.8 3.0 9.1 2.1 7.5 7.6 2.3 7.5 9.2 5.2 6.0 4.8 8.6 4.0 9.2 6.6 7.7 6.5 2.7 12.5 3.0 7.6 5.9 2.6 3.6 4.6 4.0 11.0 9.7 5.8 4.8 5.9 6.3 6.3 9.2 8.7 4.0 4.9 4.8 3.4 6.9 7.4 7.5 11.8 14.8 9.4 18.6 9.0 6.8 11.6 5.3 4.6 3.7 4.2 14.8 13.0 19.9 6.0 8.5 11.9 18.9 10.2 12.9 3.7 5.8 6.3 9.4 16.1 8.4 8.8 11.7 10.3 13.0 7.1 8.9 12.3 6.0 7.2 7.5 20.5 4.3 4.5 13.5 4.5 20.9 14.1 4.8 7.4 16.7 9.4 12.7 5.4 17.2 8.4 10.6 8.0 17.2 6.2 7.2 9.6 15.4 22.4 6.4 20.1 10.0 11.4 11.9 10.5 12.9 8.6 13.4 10.3 0.9 0.9 0.4 1.7 1.6 2.5 1.2 1.7 1.7 1.1 1.1 1.8 1.8 0.5 1.6 1.6 0.9 0.9 1.4 6.9 7.1 1.4 8.9 9.2 5.2 9.2 6.6 7.6 5.9 8.7 7.5 15.7 32.1 17.5 25.5 16.8 33.4 15.2 31.9 12.0 18.0 15.7 15.2 12.9 8.6 14.4 14.7 22.9 13.6 26.0 11.4 5.9 10.6 44.7 17.8 20.4 17.2 13.1 3.6 42.0 15.2 4.0 18.6 9.7 25.1 7.6 29.5 16.1 11.6 10.6 23.5 35.2 11.3 12.2 17.5 17.9 113.2 19.3 11.4 16.0 30.9 21.4 10.3 54.6 25.1 58.2 19.7 9.6 28.6 6.0 29.1 8.1 15.5 14.7 13.9 19.7 17.6 25.3 19.1 20.4 15.3 50.0 4.0 19.3 17.9 17.9 21.5 FOXK2 "ILF, ILF1" ENSG00000141568 "Forkhead box K2" Q01167 17 82519713-82644662 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027523, HPA073491" Approved Supported Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Mitochondria" "HPA027523: AB_10601013, HPA073491: " "unprognostic (2.39e-1)" "unprognostic (8.28e-2)" "unprognostic (2.05e-1)" "unprognostic (9.52e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.24e-6)" "unprognostic (3.35e-2)" "unprognostic (2.25e-1)" "unprognostic (5.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.26e-1)" "unprognostic (3.80e-3)" "unprognostic (2.24e-2)" "unprognostic (4.89e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" 14.0 24.0 10.7 12.6 13.2 8.0 12.1 14.7 16.3 14.2 1.2 18.1 9.3 19.7 9.8 20.2 13.2 10.0 17.1 12.4 10.5 12.7 13.1 14.2 12.5 5.8 7.1 14.7 15.4 20.0 17.7 15.7 6.3 13.3 9.4 11.6 12.1 12.5 43.0 18.8 12.1 16.4 3.0 11.6 14.7 28.1 9.4 18.4 15.4 28.4 11.9 15.5 13.4 12.7 48.4 50.4 46.3 50.9 26.2 28.5 31.0 27.6 31.6 47.4 47.9 49.1 30.1 40.7 19.6 34.4 52.3 27.6 49.7 32.0 44.4 28.3 47.9 42.3 32.7 49.4 41.0 47.3 27.2 27.2 57.2 50.4 56.8 29.2 48.9 43.7 57.7 40.7 26.3 28.8 81.8 30.4 26.5 39.7 38.2 53.0 39.4 34.2 21.7 40.1 76.2 56.1 27.4 69.0 65.1 48.8 48.7 54.3 38.3 62.2 43.2 42.2 56.6 46.7 45.1 53.5 33.4 39.0 33.4 1.5 1.0 1.2 1.4 0.7 1.1 1.5 1.1 1.4 1.2 1.0 0.8 0.9 0.1 1.6 0.9 2.0 1.3 0.6 10.7 13.2 14.7 16.3 12.4 10.5 5.8 7.1 6.3 3.0 9.4 12.7 21.5 51.3 27.1 23.5 11.5 37.2 8.0 10.6 10.2 19.2 17.7 15.7 19.5 7.2 16.2 14.7 12.5 11.9 19.3 15.6 3.9 8.7 15.6 19.4 22.4 14.9 10.9 7.8 44.6 10.7 8.8 13.2 14.3 26.7 2.5 22.1 10.8 13.4 20.0 47.1 39.6 12.6 8.2 17.3 22.0 24.1 9.3 19.2 12.4 20.6 13.9 12.3 6.2 33.2 49.1 11.4 12.4 13.2 13.3 13.6 12.2 7.1 13.9 16.7 0.0 19.8 16.6 15.0 10.3 17.0 43.0 9.7 11.6 30.6 13.0 10.7 FOXP3 "AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID" ENSG00000049768 "Forkhead box P3" Q9BZS1 X 49250438-49270477 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 7.2;lymphoid tissue: 7.4" "Cell type enhanced" "Detected in some" "granulocytes: 1.3;Hepatocytes: 1.4;Horizontal cells: 3.3;Melanocytes: 1.8;T-cells: 5.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 11 "T-reg: 53.3" "Lineage enriched" "Detected in single" 394 "T-cells: 53.3" "Cell line enhanced" "Detected in some" "HDLM-2: 2.9;MCF7: 5.2;SiHa: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026301, HPA045943" Enhanced Supported Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB026301: , HPA045943: AB_2679508" "unprognostic (2.46e-2)" "prognostic favorable (1.91e-4)" "unprognostic (4.95e-3)" "prognostic favorable (7.02e-4)" "unprognostic (2.55e-4)" "prognostic favorable (4.90e-4)" "unprognostic (2.42e-2)" "unprognostic (3.46e-1)" "unprognostic (1.04e-2)" "unprognostic (1.99e-3)" "unprognostic (8.77e-3)" "unprognostic (1.94e-1)" "unprognostic (2.73e-14)" "unprognostic (5.93e-2)" "unprognostic (4.55e-2)" "unprognostic (1.98e-1)" "unprognostic (1.39e-1)" 0.2 0.2 0.9 7.4 0.7 1.3 0.7 1.5 0.8 0.4 0.0 0.6 0.7 0.2 7.2 1.2 0.2 1.6 0.2 0.8 0.6 0.3 2.4 0.9 6.1 0.7 0.7 0.4 0.2 0.4 0.5 0.1 0.8 0.6 0.7 0.7 1.1 0.8 0.3 2.3 1.9 0.3 0.5 2.4 1.6 1.3 0.8 7.2 0.6 0.1 5.2 2.8 0.3 0.7 0.1 0.3 0.2 0.9 0.1 0.0 1.1 0.2 0.2 0.1 0.4 0.8 0.2 0.6 0.3 0.5 0.6 0.3 0.8 0.0 0.1 2.9 0.5 0.2 0.3 0.2 0.4 0.3 0.4 0.1 0.8 0.9 1.7 0.0 0.0 0.9 0.9 0.7 0.0 5.2 0.1 0.3 0.8 0.1 0.7 0.4 0.3 0.2 0.2 0.2 0.6 0.5 4.7 0.5 2.0 0.5 1.5 0.8 0.8 0.3 1.4 0.5 0.1 0.4 1.1 0.4 0.2 0.8 0.7 0.0 0.0 0.0 0.0 0.1 0.2 0.0 4.7 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 53.3 1.3 0.9 0.7 1.5 0.8 0.8 0.6 0.7 0.7 0.8 0.5 0.8 0.7 0.1 0.0 0.6 0.3 0.4 0.5 0.0 0.0 0.0 0.2 0.3 0.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 1.3 0.1 0.0 1.4 0.1 3.3 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.3 1.8 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.8 0.9 0.0 0.4 0.0 5.3 0.2 0.0 0.0 FOXRED2 "ERFAD, FLJ23322" ENSG00000100350 "FAD dependent oxidoreductase domain containing 2" Q8IWF2 22 36487190-36507043 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 5.4" "Cell line enhanced" "Detected in many" "SiHa: 147.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031611, HPA031612" Approved "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA031611: AB_10599975, HPA031612: AB_10601887" "unprognostic (3.66e-1)" "prognostic favorable (4.86e-5)" "unprognostic (6.73e-2)" "unprognostic (1.26e-1)" "unprognostic (4.66e-1)" "unprognostic (7.58e-2)" "unprognostic (2.24e-3)" "unprognostic (2.00e-2)" "unprognostic (4.31e-1)" "unprognostic (7.15e-3)" "unprognostic (1.67e-2)" "unprognostic (1.48e-2)" "unprognostic (2.15e-2)" "unprognostic (9.56e-3)" "unprognostic (4.49e-1)" "prognostic unfavorable (9.32e-4)" "unprognostic (9.42e-2)" 5.5 8.1 15.5 4.9 14.8 3.7 4.6 6.7 17.1 9.5 9.0 4.2 4.8 8.1 10.4 4.5 6.6 5.3 5.0 18.0 7.7 6.8 7.7 3.8 5.3 5.5 9.5 13.7 3.6 5.2 4.2 6.3 5.8 7.7 4.2 7.5 6.0 5.5 7.0 7.6 3.1 6.0 5.9 11.3 4.3 5.8 9.9 5.2 4.7 6.4 4.9 5.2 3.8 11.9 31.1 32.7 17.1 35.7 10.7 5.1 26.5 16.2 15.7 31.8 26.3 85.8 15.5 42.4 26.4 12.9 2.2 16.5 32.1 8.5 20.4 15.0 50.8 27.6 20.2 38.6 29.2 27.2 88.9 14.8 8.4 21.2 9.3 7.5 10.5 32.7 33.8 0.7 19.5 27.3 29.0 14.2 15.1 25.0 27.5 52.5 38.4 18.8 12.4 21.5 34.8 44.9 147.5 30.3 27.0 6.4 43.4 14.9 11.8 41.1 51.9 30.3 18.6 11.6 19.0 33.2 13.5 23.9 32.8 0.5 0.9 0.1 0.2 1.1 1.2 0.3 0.2 0.3 0.8 0.4 0.6 0.5 0.3 0.2 0.8 5.4 0.2 0.4 15.5 14.8 6.7 17.1 18.0 7.7 5.5 9.5 5.8 5.9 9.9 11.9 0.9 0.0 4.5 6.8 2.9 2.8 2.6 0.8 3.4 11.6 4.1 3.7 5.5 2.8 0.7 5.5 4.2 11.2 6.1 1.0 1.9 1.9 0.3 2.2 6.2 3.0 0.0 3.4 3.5 1.6 5.4 7.5 1.1 3.9 2.5 7.8 1.8 11.7 10.8 10.1 9.1 1.5 0.0 16.6 3.7 0.9 9.3 4.2 3.6 0.0 1.3 8.6 1.0 6.0 5.5 0.9 0.2 7.5 2.1 1.9 0.4 5.5 1.1 4.0 0.0 12.7 2.3 8.9 22.3 4.7 4.0 3.6 0.9 7.6 3.1 1.4 FP565260.1 ENSG00000275464 "Periodic tryptophan protein 2 homolog" 21 5130871-5154658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 9.1;Ductal cells: 9.3;Exocrine glandular cells: 8.0;granulocytes: 5.1;Hofbauer cells: 6.3;Pancreatic endocrine cells: 8.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 102.4" HPA024573 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 1: Pancreatic cells - Digestion" Nucleoli Cytosol "HPA024573: AB_1855963" "unprognostic (3.37e-3)" "unprognostic (4.09e-2)" "unprognostic (4.43e-1)" "unprognostic (9.66e-3)" "unprognostic (2.58e-1)" "unprognostic (1.08e-1)" "unprognostic (1.16e-3)" "unprognostic (1.34e-1)" "unprognostic (2.30e-3)" "unprognostic (8.40e-3)" "unprognostic (5.16e-2)" "unprognostic (1.07e-2)" "unprognostic (9.34e-3)" "unprognostic (1.74e-2)" "unprognostic (5.76e-2)" "unprognostic (5.96e-2)" "unprognostic (1.11e-1)" 9.2 9.2 6.4 9.9 8.8 12.1 7.4 7.2 8.0 5.9 4.9 8.5 9.1 6.8 1.7 8.3 7.8 7.3 7.5 7.1 6.8 9.0 6.8 7.1 13.4 7.6 7.2 6.7 7.7 6.5 6.0 7.9 9.1 6.5 8.4 3.5 6.7 4.7 10.1 8.6 8.2 7.3 6.8 11.5 7.6 7.1 7.2 6.7 6.6 3.2 5.3 11.4 7.1 13.7 32.0 24.0 15.4 24.2 6.6 5.0 9.1 0.2 0.0 0.1 0.1 0.4 20.1 0.3 14.1 10.5 20.8 21.0 42.9 19.0 0.0 7.4 15.1 102.4 12.4 11.9 10.4 47.6 29.1 17.8 22.5 25.5 20.1 5.0 20.1 16.5 56.8 11.6 6.6 28.4 34.4 33.1 60.4 36.5 29.3 54.0 14.2 28.8 13.5 25.3 16.6 27.3 25.5 38.4 14.9 4.2 31.5 24.9 10.2 12.0 29.7 0.3 32.9 13.9 16.0 63.5 20.4 62.3 16.7 3.3 7.3 6.9 18.5 12.6 21.2 11.0 11.3 13.5 8.7 11.2 11.1 15.2 4.1 9.9 18.2 5.5 8.5 11.6 6.4 8.8 7.2 8.0 7.1 6.8 7.6 7.2 9.1 6.8 7.2 13.7 0.9 0.0 9.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.5 1.9 0.0 0.0 2.5 0.0 0.0 2.7 1.1 0.8 0.0 9.3 0.0 0.8 1.1 0.9 0.0 0.0 0.0 8.0 1.4 0.9 0.0 0.9 5.1 0.6 0.0 0.0 6.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.1 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 2.3 1.2 0.4 0.9 0.0 FPGS ENSG00000136877 "Folylpolyglutamate synthase" Q05932 9 127794597-127814327 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050488 Approved "Intracellular and membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 14: REH - Unknown function" "Cluster 3: Monocytes - Immune response regulation" "HPA050488: AB_2681143" "unprognostic (6.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "prognostic favorable (9.08e-4)" "unprognostic (1.25e-1)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (6.25e-2)" "unprognostic (2.63e-1)" "unprognostic (1.16e-1)" "unprognostic (6.97e-2)" "unprognostic (1.76e-1)" "unprognostic (8.54e-3)" "unprognostic (2.61e-1)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" 37.3 49.1 8.7 15.5 9.7 19.7 32.6 9.1 9.3 26.6 9.2 19.5 10.5 29.6 8.4 22.1 35.5 9.1 31.2 8.3 9.2 24.8 66.1 30.6 17.7 10.3 9.6 55.4 28.0 10.2 18.0 7.7 9.3 26.6 6.9 2.2 20.4 11.6 48.2 15.5 22.8 9.4 10.2 29.9 25.8 12.9 9.2 13.4 22.1 19.0 13.2 25.6 18.2 10.1 36.2 24.4 14.2 29.7 21.2 23.1 42.6 28.0 33.0 34.4 28.0 26.4 56.7 44.4 35.8 38.9 24.4 67.0 17.7 39.4 11.4 48.5 22.6 34.5 30.4 32.1 50.5 64.2 28.1 32.2 21.2 34.7 43.8 29.4 43.3 41.6 39.8 27.7 36.2 45.8 56.6 47.8 39.9 39.2 74.0 116.0 23.0 77.7 52.2 29.3 20.5 35.0 80.1 38.6 5.8 5.7 23.7 26.8 65.4 18.6 26.0 54.1 56.8 31.0 14.2 36.0 40.7 29.4 26.7 0.2 15.4 2.3 38.8 23.9 35.1 23.2 22.9 34.0 30.8 27.6 18.5 25.2 0.8 43.6 23.9 38.9 26.6 22.4 8.7 9.7 9.1 9.3 8.3 9.2 10.3 9.6 9.3 10.2 9.2 10.1 11.3 22.4 28.1 8.8 28.6 10.5 23.7 31.1 8.6 5.5 15.7 13.3 19.5 34.3 21.6 9.2 14.6 15.5 21.8 11.6 11.7 49.6 5.0 18.0 19.9 18.7 22.9 26.7 5.8 52.9 22.0 18.0 31.6 23.9 31.0 14.6 19.2 73.2 29.8 5.0 6.4 13.8 16.2 19.5 18.4 2.2 19.0 18.9 8.8 4.7 46.2 6.5 22.6 6.0 6.2 66.9 9.9 7.2 32.7 30.8 22.1 20.1 11.2 8.5 13.1 21.9 15.2 6.0 16.0 19.9 8.8 14.8 22.2 14.5 24.2 36.5 FRAS1 "FLJ14927, FLJ22031, KIAA1500" ENSG00000138759 "Fraser extracellular matrix complex subunit 1" Q86XX4 4 78057323-78544269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.8;thyroid gland: 12.0" "Group enriched" "Detected in many" 9 "Excitatory neurons: 204.9;Inhibitory neurons: 377.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 35.9;Hep G2: 21.9;RH-30: 20.1;SiHa: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051601 Approved "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA051601: AB_2681547" "unprognostic (1.33e-2)" "unprognostic (1.04e-2)" "unprognostic (9.37e-2)" "unprognostic (8.91e-2)" "unprognostic (2.97e-1)" "unprognostic (2.04e-1)" "unprognostic (1.45e-3)" "unprognostic (2.02e-2)" "unprognostic (1.07e-1)" "unprognostic (2.69e-2)" "unprognostic (2.09e-2)" "unprognostic (4.02e-2)" "prognostic favorable (4.69e-4)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.78e-3)" "unprognostic (6.09e-2)" 2.0 0.6 3.4 0.5 5.8 0.0 0.7 0.0 7.9 2.1 4.0 3.5 0.3 2.0 1.9 1.7 1.0 0.9 1.5 3.5 3.3 7.4 0.3 3.4 0.1 3.1 3.3 0.2 5.4 0.6 2.4 5.8 3.0 2.3 1.3 2.2 1.0 0.7 2.7 1.3 1.0 1.4 0.6 0.7 0.9 0.6 13.8 2.6 12.0 2.2 0.2 0.5 1.4 4.9 4.6 6.9 2.7 0.0 7.0 2.9 4.8 1.1 4.1 0.6 0.4 5.4 9.8 0.0 8.2 35.9 0.0 1.3 3.8 2.1 0.1 0.0 3.8 4.2 8.5 21.9 0.8 0.0 0.0 14.1 2.3 0.0 5.2 5.4 0.1 0.3 0.0 0.0 4.1 0.2 0.1 0.0 8.6 3.6 1.3 0.0 20.1 0.0 8.7 9.9 5.0 9.7 21.6 6.7 1.3 12.3 0.0 0.0 0.0 0.0 4.5 2.9 1.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 5.8 0.0 7.9 3.5 3.3 3.1 3.3 3.0 0.6 13.8 4.9 0.5 32.1 0.0 9.1 0.1 1.9 2.2 2.5 10.2 10.8 0.8 1.8 7.3 22.8 9.2 29.5 0.0 28.0 0.0 0.8 3.9 7.6 2.1 5.5 1.0 2.0 1.2 0.0 204.9 1.7 1.4 5.3 4.1 13.5 0.0 0.1 1.1 0.2 4.4 0.0 377.7 1.0 0.0 0.0 0.7 2.8 0.6 0.4 1.8 20.6 0.0 0.6 0.0 10.1 5.5 2.7 2.5 0.0 0.0 1.8 1.4 4.3 2.5 2.7 0.0 1.5 3.4 0.8 1.2 10.4 1.3 15.6 0.1 2.8 2.4 0.4 FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.4" "Group enriched" "Detected in many" 7 "Early spermatids: 73.7;Inhibitory neurons: 126.1;Late spermatids: 144.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HEL: 163.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA 58000 "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.13e-5)" "unprognostic (2.59e-3)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.66e-3)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (3.62e-2)" "unprognostic (6.23e-2)" "unprognostic (8.95e-13)" "unprognostic (2.28e-3)" "unprognostic (8.53e-2)" "unprognostic (3.41e-2)" "unprognostic (2.86e-1)" 5.3 2.5 0.9 0.8 1.1 0.2 4.8 4.2 1.3 5.0 2.0 6.4 2.1 19.7 36.4 1.0 4.1 3.7 6.4 1.1 1.3 17.0 0.9 2.4 0.0 2.0 1.3 1.4 6.6 5.0 1.0 5.5 1.2 1.1 1.7 1.3 0.8 3.4 0.9 3.3 5.4 14.2 3.0 0.4 1.0 4.2 1.2 1.2 0.7 0.8 0.5 2.1 2.3 3.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.8 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.4 3.7 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 4.2 1.3 1.1 1.3 2.0 1.3 1.2 3.0 1.2 3.8 0.4 0.0 0.6 13.1 0.3 1.3 0.2 0.0 0.6 2.0 0.1 0.1 2.9 2.8 0.0 1.8 0.0 0.5 0.0 0.2 0.0 0.3 73.7 1.5 7.7 0.4 0.0 3.0 16.2 0.0 0.3 11.2 0.5 1.3 5.1 0.2 3.9 0.0 0.5 0.0 126.1 2.4 0.0 0.6 1.2 144.7 0.6 0.1 0.0 6.5 0.6 4.0 0.0 7.1 4.3 0.2 0.0 1.5 0.0 0.1 13.0 1.3 0.0 0.1 0.0 0.6 2.8 0.8 0.9 0.0 1.1 0.3 0.1 6.1 4.7 0.1 FREM3 ENSG00000183090 "FRAS1 related extracellular matrix 3" P0C091 4 143577302-143700675 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.3" "Cell type enhanced" "Detected in some" "Astrocytes: 1.6;Excitatory neurons: 9.7;Inhibitory neurons: 3.6;Oligodendrocyte precursor cells: 4.5;Oligodendrocytes: 2.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 3.1;hypothalamus: 2.8;thalamus: 4.4" HPA041641 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA041641: AB_2677592" "unprognostic (1.19e-2)" "unprognostic (4.09e-9)" "unprognostic (3.09e-3)" "unprognostic (2.74e-1)" "unprognostic (1.66e-1)" "unprognostic (4.74e-2)" "unprognostic (1.98e-1)" "unprognostic (1.91e-1)" "unprognostic (2.68e-1)" "unprognostic (2.17e-1)" "unprognostic (1.46e-1)" "unprognostic (2.30e-1)" "unprognostic (7.11e-3)" "unprognostic (3.24e-1)" 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 1.3 0.6 0.0 0.0 0.2 0.2 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.2 0.6 0.3 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 1.0 0.0 0.0 0.0 4.5 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 FRMPD2 "MGC35285, PDZD5C, PDZK5C" ENSG00000170324 "FERM and PDZ domain containing 2" Q68DX3 10 48153088-48274696 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;choroid plexus: 5.2;retina: 24.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 50.0;Cone photoreceptor cells: 287.7;Early spermatids: 97.7;Endometrial ciliated cells: 70.6;Late spermatids: 118.5;Respiratory ciliated cells: 62.9;Rod photoreceptor cells: 90.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.4;HBEC3-KT: 1.0;SCLC-21H: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 77: Retina - Visual perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (1.53e-1)" "unprognostic (3.08e-1)" "unprognostic (7.88e-4)" "unprognostic (7.59e-2)" "unprognostic (2.37e-1)" "unprognostic (2.06e-1)" "unprognostic (6.54e-3)" "unprognostic (1.85e-1)" "unprognostic (6.60e-2)" "unprognostic (1.12e-1)" "unprognostic (3.25e-12)" "unprognostic (3.48e-2)" "unprognostic (5.43e-2)" "unprognostic (1.54e-1)" "unprognostic (7.43e-5)" 0.0 0.0 2.4 0.0 2.0 0.0 0.4 2.7 1.3 0.2 5.2 0.0 0.0 0.1 0.1 0.0 3.0 0.0 0.9 2.1 2.7 0.1 0.0 0.2 0.0 4.7 6.7 0.0 0.0 0.0 0.1 0.0 4.1 0.3 0.1 24.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.3 3.5 0.0 0.5 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.3 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.0 2.7 1.3 2.1 2.7 4.7 6.7 4.1 4.0 3.5 3.4 0.0 0.0 0.5 36.6 0.0 0.1 0.4 1.6 0.0 50.0 1.1 0.4 5.0 0.0 4.6 3.7 287.7 0.2 0.0 0.1 0.0 0.1 97.7 70.6 0.5 0.3 3.0 0.0 2.0 0.0 0.3 0.8 0.0 1.6 0.0 0.0 0.0 0.2 0.1 3.3 0.9 0.6 6.1 0.0 0.0 118.5 0.3 0.2 0.0 0.0 0.0 5.2 0.0 0.5 0.3 0.2 0.1 0.4 0.0 0.4 4.2 0.5 62.9 90.8 0.0 0.2 0.6 2.1 1.0 0.0 0.3 0.0 0.1 0.1 0.7 0.4 FRZB "FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3" ENSG00000162998 "Frizzled related protein" Q92765 2 182833275-182866637 "Disease related genes, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 336.9" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 3633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.2;ASC diff: 9.4;NTERA-2: 7.4;SH-SY5Y: 6.5" "Region enhanced" "Detected in all" "olfactory bulb: 56.9" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 44000 "Cluster 19: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.39e-2)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.79e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.64e-2)" "unprognostic (2.38e-2)" "unprognostic (4.67e-2)" "unprognostic (8.58e-2)" "unprognostic (5.41e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (3.53e-2)" "unprognostic (1.05e-2)" "unprognostic (6.04e-2)" "unprognostic (3.21e-1)" 10.4 5.7 10.4 6.1 12.8 0.7 12.6 11.0 18.6 20.3 52.2 16.2 14.4 17.2 11.4 12.4 7.1 39.0 19.9 10.3 11.2 16.3 3.3 9.1 18.7 14.1 10.9 13.5 7.1 6.7 18.6 30.5 15.4 12.9 19.9 336.9 4.7 16.6 26.6 10.4 14.5 31.1 11.9 88.9 21.9 14.2 11.3 4.9 10.8 116.2 11.9 10.3 12.3 10.3 0.0 0.0 19.2 0.2 9.4 0.2 0.2 0.0 0.9 3.2 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 7.4 0.0 0.0 0.6 0.8 0.0 0.0 0.0 1.0 6.5 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 12.8 11.0 18.6 10.3 11.2 14.1 10.9 15.4 11.9 11.3 10.3 13.8 0.0 0.5 1.0 0.8 8.2 0.4 0.2 0.6 39.8 7.8 18.7 2.9 0.0 1.4 0.0 33.3 5.3 0.5 2.1 0.0 0.1 0.3 0.5 1.4 18.5 1.2 0.0 2.7 8.2 3.8 97.8 9.7 0.9 0.0 0.5 3.6 1.0 7.8 26.9 7.7 137.4 0.0 0.8 3.7 2.8 3.7 0.5 245.5 25.3 0.0 3633.8 0.0 8.5 1.7 0.2 0.8 14.7 5.8 1.8 1.3 0.2 0.2 124.4 276.1 41.9 157.1 0.2 0.1 0.6 3.1 12.4 1.5 22.9 3.4 0.6 FSHB ENSG00000131808 "Follicle stimulating hormone subunit beta" P01225 11 30231014-30235261 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 436 "pituitary gland: 239.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB023410, HPA069703" Enhanced "Secreted to blood" NA NA 78000 "Cluster 26: Pituitary gland - Hormone signaling" "CAB023410: AB_324983, HPA069703: AB_2686176" "unprognostic (1.04e-1)" 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 239.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FSHR "FSHRO, LGR1, ODG1" ENSG00000170820 "Follicle stimulating hormone receptor" P23945 2 48962157-49154527 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 1.0;ovary: 2.0;testis: 2.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 10.1;Granulosa cells: 33.8;Late spermatids: 7.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (5.94e-2)" "unprognostic (4.06e-3)" "unprognostic (5.78e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.6 0.8 2.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.3 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.0 0.6 0.8 0.4 0.3 0.5 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.1 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 FST FS ENSG00000134363 Follistatin P19883 5 53480626-53487134 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 68.7" "Cell type enriched" "Detected in many" 6 "Granulosa cells: 700.1" "Cancer enhanced" "Detected in all" "liver cancer: 45.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 351.1;HaCaT: 292.3;HBEC3-KT: 191.3;HMC-1: 206.5;PC-3: 558.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA016612, CAB026025" Approved Approved Vesicles "Secreted to blood" NA NA 1800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "CAB026025: , HPA016612: " "unprognostic (1.43e-1)" "unprognostic (6.50e-2)" "unprognostic (1.44e-1)" "unprognostic (7.73e-3)" "unprognostic (2.30e-1)" "unprognostic (1.50e-3)" "unprognostic (8.02e-2)" "unprognostic (2.32e-2)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.44e-5)" "unprognostic (1.21e-3)" "unprognostic (2.48e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-1)" 26.1 6.2 0.8 3.0 0.5 0.4 15.2 0.4 0.7 7.7 0.7 9.8 1.8 4.2 3.7 6.5 11.8 7.2 9.4 2.0 2.0 2.9 68.7 8.2 1.6 1.8 1.0 9.9 2.6 0.5 5.9 24.1 0.9 15.5 3.0 0.3 11.3 10.8 9.2 18.0 8.8 4.7 0.5 0.3 11.1 5.0 1.1 2.3 4.0 7.7 12.9 40.4 7.5 0.7 20.0 1.8 33.7 0.0 38.6 13.5 55.4 76.3 351.1 46.4 45.4 0.3 0.2 0.0 0.6 19.9 2.3 292.3 0.0 191.3 32.7 0.8 0.2 4.0 1.7 31.3 20.4 0.3 206.5 31.0 0.5 84.5 55.0 31.3 40.0 0.0 0.0 0.6 29.7 0.1 0.1 1.6 52.1 0.0 558.2 4.2 43.6 0.0 0.0 31.9 0.5 0.1 3.1 0.2 2.0 83.9 0.3 0.3 0.2 124.1 35.3 13.2 11.1 0.4 0.1 0.1 14.8 4.1 116.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.5 0.4 0.7 2.0 2.0 1.8 1.0 0.9 0.5 1.1 0.7 5.2 0.0 1.1 0.0 1.0 20.0 31.5 64.4 13.1 0.0 0.9 23.4 11.4 0.0 8.3 0.0 0.0 0.6 0.0 0.0 0.0 1.6 0.4 0.1 3.4 2.9 0.0 0.0 0.1 4.6 14.8 107.7 3.6 0.1 0.0 700.1 1.1 57.2 1.8 0.0 0.7 0.0 2.0 0.8 16.4 1.5 3.1 1.5 5.4 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 11.3 0.2 37.1 0.0 0.1 1.6 0.0 13.1 29.6 33.3 0.3 12.2 4.0 4.7 6.0 2.0 0.3 0.0 51.8 FSTL1 "FRP, FSL1, OCC-1, OCC1, tsc36" ENSG00000163430 "Follistatin like 1" Q12841 3 120392293-120450993 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 352.1;Fibroblasts: 521.9;Leydig cells: 327.4;Peritubular cells: 270.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 12.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 12.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 1782.4;BJ: 2156.3;fHDF/TERT166: 2692.9;HBF TERT88: 1741.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035251, HPA040815" Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 34000000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA035251: AB_10601906, HPA040815: AB_2732489" "unprognostic (2.60e-1)" "unprognostic (1.59e-3)" "unprognostic (8.84e-2)" "unprognostic (4.54e-3)" "unprognostic (4.10e-2)" "unprognostic (1.35e-1)" "unprognostic (9.88e-2)" "unprognostic (3.05e-2)" "unprognostic (1.19e-2)" "unprognostic (3.88e-2)" "unprognostic (3.54e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (4.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.05e-2)" "unprognostic (4.47e-3)" 432.4 134.3 20.5 116.3 18.1 2.2 166.1 22.8 22.7 279.9 83.0 156.4 37.1 157.5 50.8 126.1 150.6 257.0 242.7 20.6 22.8 45.4 35.7 120.7 50.3 28.5 44.6 90.3 37.3 35.5 25.7 442.0 23.1 188.3 90.4 29.8 59.3 184.4 31.8 64.2 69.1 409.6 22.7 63.1 68.6 33.5 22.7 24.2 78.8 89.8 38.8 260.4 104.3 20.6 81.0 21.2 222.9 91.8 1304.4 1782.4 1.3 2156.3 1208.9 1374.5 1211.0 0.1 178.5 0.8 178.8 2692.9 112.8 20.5 68.6 270.0 1741.5 1.1 32.5 0.4 159.8 0.3 286.0 1.2 0.9 1362.7 8.5 884.5 192.7 612.1 811.6 11.2 0.5 0.3 227.6 0.5 22.6 2.0 181.3 0.4 181.9 0.7 92.7 1.0 150.4 1.7 39.2 93.5 764.6 13.6 76.5 462.6 23.5 6.2 986.8 507.4 479.8 268.0 323.8 1.0 1.1 2.3 177.4 0.9 67.0 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 2.6 20.5 18.1 22.8 22.7 20.6 22.8 28.5 44.6 23.1 22.7 22.7 20.6 76.9 64.1 9.4 56.5 1.1 64.1 31.9 36.4 10.2 2.3 25.6 24.6 127.5 8.6 42.5 23.9 0.0 114.4 2.5 0.9 0.0 62.6 2.3 44.4 176.7 111.4 3.0 3.6 9.6 5.8 352.1 521.9 3.1 23.0 1.3 66.5 142.5 17.4 20.6 1.7 16.2 0.2 8.2 10.8 91.6 9.8 327.4 11.5 110.3 30.0 9.9 116.1 0.0 9.5 0.9 117.8 0.7 270.8 0.9 108.4 0.0 5.5 74.9 4.3 59.2 62.5 129.3 1.5 4.4 2.2 48.2 54.7 7.1 47.5 0.9 65.3 FSTL3 "FLRG, FSRP" ENSG00000070404 "Follistatin like 3" O95633 19 676392-683392 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Osteogenesis, Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 3647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 164.7;hTCEpi: 181.2;SiHa: 341.5;U-2197: 173.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB024899, HPA045378" Approved Supported Nucleoplasm "Secreted in other tissues" NA Yes 7000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB024899: , HPA045378: AB_2679300" "unprognostic (9.86e-3)" "unprognostic (1.32e-3)" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (3.03e-4)" "unprognostic (2.19e-3)" "unprognostic (1.51e-3)" "unprognostic (8.64e-3)" "prognostic unfavorable (4.61e-7)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.65e-4)" "unprognostic (3.50e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-3)" "unprognostic (7.22e-3)" "unprognostic (3.07e-1)" "unprognostic (3.75e-1)" "unprognostic (5.89e-3)" 82.9 163.3 16.6 24.1 15.3 13.3 62.4 13.3 19.8 75.6 16.0 82.7 7.7 62.0 6.1 22.0 70.2 16.5 124.1 16.4 17.3 55.9 26.2 132.7 5.5 22.6 16.0 63.8 49.3 3.2 28.9 179.4 17.9 74.9 5.9 2.4 21.1 22.1 11.7 32.3 36.5 42.4 16.7 22.6 43.2 75.2 18.1 2.3 37.9 4.9 1.6 70.5 63.1 18.9 9.5 74.0 5.1 3.7 22.3 56.4 164.7 126.1 18.5 30.7 11.3 27.1 14.4 4.1 49.4 84.7 17.6 65.2 4.1 106.4 10.1 7.8 8.7 3.5 110.2 22.4 95.6 6.7 12.0 70.7 181.2 34.0 140.2 79.3 5.5 3.9 8.2 5.3 46.7 33.1 2.4 4.0 6.2 62.0 26.2 7.2 3.4 8.7 43.1 1.7 3.3 5.7 341.5 6.9 4.3 6.4 6.2 3.5 75.5 30.6 106.6 173.4 46.9 8.5 4.4 2.3 4.7 20.0 14.2 0.0 1.9 0.0 0.4 1.8 0.0 0.1 0.6 0.4 0.9 0.3 1.0 0.6 0.0 0.2 1.4 0.3 0.0 0.9 16.6 15.3 13.3 19.8 16.4 17.3 22.6 16.0 17.9 16.7 18.1 18.9 4.6 19.2 1.9 40.5 1.5 14.5 31.0 11.7 1.8 1.3 11.3 7.9 16.7 32.9 4.4 9.2 0.0 53.9 1.0 1.1 7.9 86.1 8.8 6.4 14.8 8.7 1.2 1.7 9.8 64.3 3647.6 59.6 2.0 18.3 0.0 5.7 16.4 1.9 77.1 3.3 8.4 1.0 0.0 3.7 4.8 7.6 61.2 7.4 5.4 2.8 10.6 6.6 1.0 6.0 5.5 306.5 0.2 26.7 1.0 78.0 1.2 17.7 3.1 1.1 46.0 22.4 57.0 4.6 5.6 4.3 7.7 792.0 2.0 3.6 2.5 30.7 FSTL4 KIAA1061 ENSG00000053108 "Follistatin like 4" Q6MZW2 5 133196455-133612541 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.4" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 390.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SCLC-21H: 57.2;U-266/70: 19.3;U-266/84: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045920 Uncertain Uncertain Mitochondria "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA045920: AB_10965844" "unprognostic (5.52e-2)" "unprognostic (2.54e-1)" "unprognostic (5.74e-2)" "unprognostic (8.14e-2)" "unprognostic (1.87e-1)" "unprognostic (3.97e-2)" "unprognostic (6.35e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (4.74e-2)" "unprognostic (8.66e-2)" "unprognostic (3.73e-4)" "unprognostic (2.02e-2)" "unprognostic (9.91e-3)" "unprognostic (1.03e-2)" "unprognostic (4.25e-2)" 0.1 1.3 5.5 0.6 5.5 1.9 0.6 8.5 11.2 0.3 0.0 1.1 0.7 0.2 1.5 1.9 0.9 0.5 0.3 3.1 3.2 2.8 0.1 1.2 0.3 0.0 6.2 0.4 1.9 3.1 2.3 3.8 0.0 1.6 1.1 3.9 0.7 0.0 0.9 3.4 0.8 0.2 0.0 0.4 1.4 1.7 21.4 1.3 0.8 0.5 1.1 6.0 0.9 7.8 7.5 13.1 1.4 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 12.5 1.7 0.7 10.5 0.0 1.3 0.2 1.7 0.5 0.0 0.9 0.6 0.6 13.9 1.1 0.0 0.0 0.7 0.3 1.8 0.0 0.1 0.3 0.0 0.5 5.9 7.0 0.0 12.7 1.5 0.6 14.4 14.2 1.6 0.6 1.3 14.1 0.0 15.0 57.2 1.6 2.9 2.4 0.3 12.2 4.6 0.5 0.3 0.6 2.4 0.8 0.4 19.3 20.7 0.5 0.2 0.1 0.4 1.1 0.2 0.1 0.2 0.0 0.5 0.6 0.4 0.3 0.1 0.5 0.4 0.2 0.5 0.2 0.2 0.3 0.3 0.3 5.5 5.5 8.5 11.2 3.1 3.2 0.0 6.2 0.0 0.0 21.4 7.8 0.0 0.0 3.1 21.5 1.0 1.7 2.5 0.2 4.0 10.1 0.6 0.3 9.6 0.0 4.4 0.0 14.6 0.4 0.1 0.0 0.0 0.2 35.9 1.2 0.2 0.6 9.0 0.0 390.3 0.0 0.0 0.4 0.0 0.1 0.0 1.4 0.0 0.0 0.1 1.7 57.9 0.4 0.0 0.0 0.0 20.4 0.3 1.2 10.6 8.4 0.0 3.0 0.0 21.1 4.5 0.6 0.0 0.7 0.0 0.4 0.2 2.5 3.7 2.6 6.6 0.0 1.1 0.5 0.7 3.3 1.6 0.0 0.4 0.9 0.1 2.9 FSTL5 "DKFZp566D234, KIAA1263" ENSG00000168843 "Follistatin like 5" Q8N475 4 161383897-162164004 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 68.6;retina: 94.8" "Group enriched" "Detected in some" 4 "Bipolar cells: 306.0;Cone photoreceptor cells: 462.9;Excitatory neurons: 184.7;Inhibitory neurons: 517.7;Rod photoreceptor cells: 139.6" "Cancer enriched" "Detected in single" 6 "melanoma: 1.7" "Region enriched" "Detected in all" 5 "cerebellum: 68.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 75.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 57.3" "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (4.90e-2)" "unprognostic (4.46e-1)" "unprognostic (1.52e-2)" "unprognostic (2.03e-1)" "unprognostic (3.66e-2)" "unprognostic (2.99e-2)" "unprognostic (3.00e-1)" "unprognostic (2.05e-2)" "unprognostic (1.10e-1)" "unprognostic (3.39e-2)" "unprognostic (1.61e-1)" "unprognostic (1.08e-10)" "unprognostic (8.45e-4)" "unprognostic (1.53e-1)" "unprognostic (1.52e-1)" "unprognostic (6.60e-3)" 0.0 6.0 7.4 0.0 6.9 0.0 0.0 68.6 3.7 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.1 15.2 0.0 0.0 0.0 0.0 12.7 9.9 0.0 0.3 0.0 1.2 0.1 14.4 0.0 0.1 94.8 0.0 0.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.6 9.6 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 2.1 0.0 0.9 0.0 0.0 0.0 12.4 0.1 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 75.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 10.8 0.0 0.0 0.7 0.1 0.0 0.3 0.1 0.0 0.0 16.2 0.0 6.2 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 6.9 68.6 3.7 3.1 15.2 12.7 9.9 14.4 6.2 9.6 5.1 0.0 0.0 0.0 47.7 0.0 0.3 0.0 0.0 0.0 306.0 0.0 0.0 0.1 0.0 0.0 0.0 462.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.8 0.0 0.0 184.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 28.6 517.7 0.0 0.0 0.3 0.3 4.5 0.6 0.0 1.8 7.5 0.0 20.7 0.0 8.0 75.3 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.0 139.6 0.0 0.0 0.0 0.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FTCDNL1 FONG ENSG00000226124 "Formiminotransferase cyclodeaminase N-terminal like" E5RQL4 2 199760544-199851192 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Excitatory neurons: 43.5;Oligodendrocytes: 115.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA065748 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA065748: " "unprognostic (1.78e-1)" "unprognostic (1.70e-1)" "unprognostic (1.27e-2)" "unprognostic (9.80e-2)" "unprognostic (3.09e-1)" "unprognostic (7.21e-2)" "unprognostic (1.54e-3)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (5.37e-2)" "unprognostic (9.86e-2)" "prognostic favorable (3.31e-4)" "unprognostic (3.92e-2)" "unprognostic (4.63e-2)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.21e-2)" 2.4 4.9 4.4 0.9 7.9 2.3 2.1 5.4 5.5 0.6 1.8 1.1 1.0 0.4 1.8 1.3 1.9 0.9 2.9 4.5 4.8 4.2 10.0 1.4 2.0 6.1 6.7 1.0 2.2 1.5 0.9 0.6 5.7 1.2 1.1 1.4 2.4 0.6 8.1 1.2 0.8 1.1 6.1 4.6 0.9 1.0 6.0 0.7 5.7 8.4 0.8 0.7 0.9 7.6 0.6 1.9 0.1 0.0 1.9 1.1 1.4 0.7 0.7 1.0 0.4 0.0 3.5 2.0 0.2 0.8 5.7 0.0 0.9 5.3 1.2 2.3 0.5 1.5 0.8 1.7 0.7 5.5 6.5 0.8 0.2 0.4 0.1 0.7 0.0 4.9 2.7 0.1 0.7 6.0 1.9 2.1 1.6 0.5 4.0 0.3 0.2 0.0 0.4 0.0 2.3 0.0 3.4 3.2 3.2 1.3 4.8 7.1 0.6 2.7 0.0 1.8 1.1 4.7 2.9 1.1 5.2 2.7 1.3 0.0 4.1 1.7 0.4 5.5 1.7 3.4 1.7 0.6 5.8 2.1 1.1 1.8 0.0 1.1 5.1 8.7 0.0 1.4 4.4 7.9 5.4 5.5 4.5 4.8 6.1 6.7 5.7 6.1 6.0 7.6 0.8 0.0 0.0 39.8 3.2 2.7 2.9 0.0 13.6 3.3 6.2 5.5 5.7 4.3 1.3 3.7 4.2 1.5 3.3 0.3 1.9 0.2 2.4 8.4 0.8 1.5 0.0 5.9 43.5 0.7 1.4 1.4 4.6 3.3 0.0 5.9 2.2 6.9 7.4 1.7 23.5 1.2 0.0 8.1 4.7 1.0 0.3 8.2 7.2 17.8 2.1 1.7 0.0 24.6 115.4 0.3 0.1 0.4 1.4 2.6 1.0 10.6 0.0 6.5 0.0 2.4 3.4 0.4 2.0 6.9 2.3 0.3 1.5 10.3 1.1 1.2 FTO "ALKBH9, KIAA1752, MGC5149" ENSG00000140718 "FTO alpha-ketoglutarate dependent dioxygenase" Q9C0B1 16 53701692-54158512 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 173.3;Excitatory neurons: 226.1;Inhibitory neurons: 240.7;Oligodendrocyte precursor cells: 210.6;Oligodendrocytes: 282.5;Respiratory ciliated cells: 182.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017123, HPA041086, HPA068695" Enhanced Supported Vesicles,Cytosol No No 540000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Vesicles "CAB017123: , HPA041086: AB_2677293, HPA068695: AB_2732117" "unprognostic (9.74e-2)" "unprognostic (2.49e-1)" "unprognostic (9.30e-2)" "unprognostic (1.24e-2)" "unprognostic (1.81e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (1.41e-1)" "unprognostic (8.67e-2)" "unprognostic (1.02e-1)" "unprognostic (3.88e-2)" "unprognostic (6.80e-2)" "unprognostic (1.44e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-1)" "unprognostic (4.30e-3)" "unprognostic (6.11e-3)" 24.4 33.6 31.8 12.5 36.6 8.2 36.3 30.1 37.7 25.8 31.0 22.2 7.7 26.9 21.4 17.2 25.3 21.6 27.1 35.2 39.5 25.0 17.4 36.8 15.0 29.2 31.3 27.2 20.7 40.6 26.2 20.1 31.9 20.0 14.1 38.4 18.9 23.9 33.1 21.4 12.5 29.9 30.5 16.4 15.0 8.3 33.8 17.0 27.5 23.0 14.8 21.9 18.5 43.9 15.1 26.8 35.0 35.9 67.3 50.4 11.5 35.6 32.2 29.3 8.5 16.8 19.3 34.4 38.2 46.3 16.6 21.7 32.4 34.9 42.5 16.0 25.5 15.5 33.6 31.7 46.2 12.5 17.1 55.9 36.5 26.6 32.5 36.6 44.1 25.1 15.2 8.4 48.1 11.8 28.0 19.2 18.1 15.5 17.5 42.2 52.9 32.3 44.6 12.3 43.0 29.7 40.4 23.6 10.8 33.7 31.1 29.3 42.4 36.4 23.9 19.8 22.1 15.9 13.9 35.0 33.9 22.9 28.7 14.9 17.9 9.7 25.6 22.7 32.4 17.6 24.4 25.9 23.8 17.4 22.5 24.4 2.9 26.4 16.5 9.5 26.6 23.1 31.8 36.6 30.1 37.7 35.2 39.5 29.2 31.3 31.9 30.5 33.8 43.9 15.1 80.1 62.0 173.3 10.3 12.4 10.0 8.6 13.6 22.8 69.1 39.5 22.3 15.7 54.4 7.3 12.5 9.3 10.2 4.8 7.9 9.0 39.1 11.0 18.3 17.4 6.6 9.7 226.1 5.7 7.4 23.1 9.7 9.9 25.9 16.8 11.0 13.8 9.2 16.8 240.7 6.6 10.2 9.0 13.2 69.9 14.3 11.8 10.6 134.0 5.5 19.6 10.3 210.6 282.5 5.5 5.0 15.1 18.7 6.0 4.5 15.8 182.7 14.1 13.1 21.6 16.8 3.5 3.4 11.0 9.1 5.1 12.9 17.8 6.3 7.9 FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 181.7;Distal enterocytes: 226.6;Paneth cells: 221.0;Proximal enterocytes: 210.9;Syncytiotrophoblasts: 200.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 165.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 60000000 "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" 34.2 34.4 8.3 49.8 8.2 7.7 26.3 8.3 11.2 54.5 23.8 124.2 90.3 20.7 113.0 17.0 51.1 46.6 20.6 8.3 10.5 78.2 104.8 55.1 168.2 9.5 8.8 23.8 23.9 56.9 17.6 72.6 9.6 50.2 140.7 5.7 40.8 60.4 15.8 14.9 81.3 26.7 9.3 71.8 63.9 27.7 10.8 26.8 70.6 17.7 94.1 74.9 13.2 12.8 15.9 10.6 2.2 31.9 4.2 0.3 11.0 16.6 34.4 17.1 31.6 14.5 165.1 23.9 40.9 21.3 18.8 9.4 15.3 35.4 22.4 16.9 25.6 19.7 9.2 32.7 14.2 2.0 62.7 15.3 19.7 6.2 8.1 55.2 6.9 13.3 9.3 0.5 20.6 17.5 5.0 17.7 5.4 48.1 16.9 26.9 0.2 26.2 63.5 40.5 10.9 10.6 47.9 18.5 26.2 17.9 13.6 7.8 1.8 5.8 9.0 38.9 5.6 28.5 31.0 8.5 14.5 58.9 9.5 54.8 100.4 51.9 27.2 99.9 23.1 23.8 19.5 22.9 44.0 14.1 18.9 22.0 12.8 44.6 91.1 25.4 21.4 64.8 8.3 8.2 8.3 11.2 8.3 10.5 9.5 8.8 9.6 9.3 10.8 12.8 12.9 25.6 28.6 4.2 10.5 3.6 27.4 99.3 6.8 4.4 22.2 10.4 5.6 40.0 77.8 84.6 0.0 181.7 13.9 226.6 15.6 64.1 61.0 31.5 2.8 11.6 10.8 20.6 5.8 50.3 24.2 16.7 33.1 13.3 8.2 11.1 25.7 42.7 156.4 0.0 6.3 44.4 44.7 121.0 13.5 24.4 23.3 85.4 8.8 2.8 29.6 13.0 10.3 4.0 4.7 34.9 221.0 19.5 8.7 23.6 210.9 40.2 53.7 5.0 6.6 16.7 13.2 109.0 24.8 8.5 2.8 200.6 11.2 34.6 79.5 40.3 FUCA2 "dJ20N2.5, MGC1314" ENSG00000001036 "Alpha-L-fucosidase 2" Q9BTY2 6 143494812-143511720 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 165.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031659, HPA031661" Approved "Secreted to blood" NA NA 56000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA031659: AB_10600661, HPA031661: AB_10601681" "unprognostic (1.83e-2)" "unprognostic (1.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (2.70e-9)" "unprognostic (1.54e-3)" "unprognostic (1.08e-1)" "unprognostic (7.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.90e-1)" "unprognostic (8.76e-3)" "unprognostic (9.18e-2)" "unprognostic (2.69e-1)" "unprognostic (7.25e-2)" "unprognostic (5.07e-2)" 28.9 41.4 13.5 25.4 16.4 25.8 26.3 16.0 15.3 29.2 30.2 41.5 42.6 25.6 44.9 14.2 23.7 27.8 27.9 12.4 16.5 54.8 52.3 28.9 17.2 17.1 14.2 30.4 34.6 165.8 15.8 50.5 17.8 21.9 52.8 6.1 25.4 25.8 6.9 12.3 39.3 27.6 16.4 24.6 38.3 12.6 15.9 6.6 32.0 11.6 17.0 33.5 20.4 20.9 97.4 55.7 47.6 86.9 69.0 134.4 90.1 89.9 95.4 108.1 182.0 107.1 94.8 0.2 66.1 120.8 33.9 0.6 24.1 11.7 148.9 87.2 92.6 32.6 100.1 163.2 99.3 0.3 15.8 72.3 69.4 96.6 41.5 91.6 111.4 0.2 117.6 49.3 123.2 114.6 0.2 75.9 62.1 44.2 76.0 0.2 99.7 72.1 129.0 59.5 36.0 23.6 98.7 65.3 82.3 36.3 32.1 79.6 65.9 64.1 54.0 161.6 175.4 18.3 21.3 0.7 74.1 59.1 22.5 38.8 84.9 26.2 13.2 84.0 15.0 11.3 9.8 11.3 65.4 8.3 4.4 7.9 5.5 29.6 62.0 10.3 19.8 51.9 13.5 16.4 16.0 15.3 12.4 16.5 17.1 14.2 17.8 16.4 15.9 20.9 27.3 41.7 35.9 9.1 13.5 11.2 12.6 30.3 9.1 3.7 19.2 12.6 28.0 38.6 37.9 25.8 0.0 52.5 10.3 47.6 11.7 81.9 2.0 26.8 55.2 25.0 9.6 18.7 8.7 124.9 109.8 62.6 34.7 28.9 37.4 38.1 23.6 35.2 110.3 1.7 11.8 38.1 46.8 57.5 29.2 2.6 66.8 51.7 42.7 9.4 49.1 11.1 13.4 5.5 14.5 74.6 38.2 45.5 47.7 13.8 60.3 51.4 34.8 1.1 6.6 33.8 35.0 4.8 4.6 13.2 8.0 46.4 11.5 78.8 50.4 18.4 FUT10 ENSG00000172728 "Fucosyltransferase 10" Q6P4F1 8 33370824-33473146 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 140.0;Early spermatids: 248.8;Late spermatids: 334.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053970, HPA058655" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Endoplasmic reticulum, Golgi apparatus" "HPA053970: AB_2682327, HPA058655: AB_2683789" "unprognostic (6.02e-2)" "unprognostic (4.61e-2)" "unprognostic (2.85e-3)" "unprognostic (6.24e-2)" "unprognostic (1.01e-1)" "unprognostic (4.80e-2)" "unprognostic (5.40e-3)" "unprognostic (6.07e-2)" "unprognostic (2.84e-1)" "unprognostic (2.23e-1)" "unprognostic (9.10e-3)" "unprognostic (2.76e-4)" "unprognostic (3.06e-3)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-3)" "unprognostic (6.01e-3)" 1.9 2.2 4.3 1.0 4.7 0.8 3.4 4.2 4.2 4.0 2.0 2.5 2.5 3.1 1.2 1.9 3.3 1.8 1.7 3.0 3.3 3.1 2.0 2.4 1.8 4.3 5.5 5.2 2.6 5.1 1.3 3.5 3.3 2.2 2.7 5.2 2.7 2.1 0.6 3.2 2.6 2.9 2.7 1.5 2.3 1.5 4.8 2.9 2.8 1.2 2.2 2.2 2.2 2.5 2.4 4.5 6.8 8.3 10.8 10.8 3.4 4.3 7.1 4.2 5.4 6.3 3.6 2.7 5.1 5.8 3.5 5.9 10.4 4.1 4.1 5.8 3.8 8.6 3.6 7.0 4.9 1.9 2.9 8.0 7.0 1.1 5.4 8.8 8.6 4.4 8.0 3.2 3.9 1.4 6.6 2.8 9.1 6.4 3.0 4.8 5.1 1.4 6.1 5.4 2.4 2.3 2.5 3.7 5.1 7.0 3.8 1.9 6.6 3.2 1.4 8.1 3.6 1.3 2.2 1.8 2.0 5.4 3.4 0.4 0.6 0.7 1.3 0.2 1.4 1.0 0.7 1.2 1.3 0.3 0.8 0.8 0.4 1.6 0.2 0.7 1.7 0.6 4.3 4.7 4.2 4.2 3.0 3.3 4.3 5.5 3.3 2.7 4.8 2.5 4.5 3.2 2.0 140.0 2.5 2.7 2.7 3.4 4.0 2.9 3.7 3.8 2.5 2.8 3.2 3.7 10.4 12.0 3.0 1.5 1.9 4.5 248.8 2.8 5.7 3.8 3.6 3.8 16.3 4.0 7.0 5.8 6.1 3.0 5.7 10.1 5.3 3.6 3.4 3.3 20.2 3.2 4.1 2.2 1.8 334.2 6.8 2.2 1.8 29.0 3.0 29.9 5.2 44.2 16.4 4.0 1.0 4.9 5.0 1.4 5.3 3.0 2.0 11.0 0.0 5.7 4.6 7.0 2.7 5.5 1.7 6.0 2.6 6.5 3.6 1.3 FUT11 MGC33202 ENSG00000196968 "Fucosyltransferase 11" Q495W5 10 73772276-73780251 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 171.6;Late spermatids: 234.7;NK-cells: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014033 Approved Approved "Nuclear membrane,Golgi apparatus" "Intracellular and membrane" NA NA 1200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Nuclear membrane" "Golgi apparatus" "HPA014033: AB_1849192" "prognostic unfavorable (6.78e-4)" "prognostic unfavorable (2.39e-6)" "unprognostic (1.47e-2)" "unprognostic (2.42e-3)" "unprognostic (3.27e-1)" "unprognostic (7.64e-2)" "unprognostic (2.29e-2)" "unprognostic (3.50e-3)" "unprognostic (1.51e-1)" "unprognostic (9.30e-2)" "unprognostic (9.77e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.67e-4)" "unprognostic (2.59e-2)" "unprognostic (1.71e-1)" "unprognostic (3.61e-1)" "unprognostic (2.66e-2)" 9.4 5.1 2.5 6.8 3.2 6.4 5.2 4.4 2.8 8.9 1.8 4.5 3.1 6.0 3.2 7.0 4.7 9.0 9.4 2.1 3.8 4.7 5.1 8.7 6.4 4.9 4.8 6.3 4.1 3.7 3.1 17.4 4.1 4.3 3.8 10.0 4.1 6.4 4.1 4.5 3.7 8.3 4.1 10.2 4.9 10.2 5.0 4.3 7.0 4.8 6.2 7.0 4.8 4.9 26.4 14.2 9.9 20.8 19.2 22.2 2.9 13.1 31.3 16.3 31.7 4.7 13.8 6.1 9.3 21.7 5.5 10.9 5.2 13.3 18.1 14.4 10.9 8.1 11.4 7.6 7.5 11.6 24.5 14.8 3.0 15.5 15.9 50.3 30.1 2.7 8.1 10.5 16.4 3.2 2.0 6.0 4.7 2.5 35.1 2.8 6.1 7.2 5.9 4.7 3.0 9.6 11.5 12.0 7.5 8.4 8.2 5.0 31.3 21.1 9.0 10.6 16.4 13.8 5.1 1.4 29.6 10.2 7.0 5.4 1.4 1.4 20.0 1.6 14.2 2.1 5.9 14.3 1.7 1.8 4.3 8.9 0.3 10.9 1.8 3.5 2.6 6.9 2.5 3.2 4.4 2.8 2.1 3.8 4.9 4.8 4.1 4.1 5.0 4.9 22.4 16.0 13.1 6.2 12.1 13.6 5.6 22.7 5.2 14.6 6.1 6.1 12.2 7.2 9.8 11.0 14.6 10.7 23.1 4.9 0.0 13.3 171.6 6.7 12.0 28.0 4.8 15.8 6.0 6.8 25.2 15.8 2.6 10.5 14.0 7.1 38.2 5.2 12.5 20.2 5.7 4.6 2.0 18.1 16.7 234.7 16.1 11.0 17.8 11.2 11.4 8.3 69.0 5.0 6.5 10.3 5.2 14.7 10.2 8.9 2.6 3.4 9.8 13.0 6.6 14.3 11.7 20.7 19.0 5.5 11.5 9.7 19.9 6.8 3.1 6.4 FUT6 "FCT3A, FLJ40754, FT1A, FucT-VI" ENSG00000156413 "Fucosyltransferase 6" P51993 19 5830408-5839722 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 79.4;kidney: 36.1;salivary gland: 45.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 35.6;Intestinal goblet cells: 39.4;Paneth cells: 21.5;Proximal enterocytes: 101.4;Proximal tubular cells: 45.3;Undifferentiated cells: 29.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 6 "Hep G2: 10.5;RPMI-8226: 4.0" "HPA043707, HPA046966" Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 51000 "Cluster 10: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "HPA043707: AB_2678628, HPA046966: AB_2679879" "unprognostic (3.65e-2)" "unprognostic (3.00e-3)" "unprognostic (2.13e-3)" "unprognostic (2.78e-3)" "unprognostic (6.35e-2)" "prognostic favorable (2.12e-4)" "unprognostic (8.02e-2)" "unprognostic (6.68e-3)" "unprognostic (4.01e-2)" "unprognostic (8.53e-2)" "unprognostic (2.62e-2)" "unprognostic (4.94e-2)" "prognostic favorable (3.17e-8)" "unprognostic (1.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" 0.1 0.0 0.1 2.6 0.1 0.4 1.7 0.2 0.1 17.3 0.4 17.3 28.6 0.3 0.0 79.4 0.6 9.3 0.0 0.1 0.1 36.1 12.4 0.2 0.1 0.1 0.1 0.0 3.7 0.0 0.0 0.0 0.1 0.2 11.6 2.0 45.7 2.5 0.0 0.1 27.0 0.4 0.1 0.1 4.8 0.2 0.1 0.0 0.0 0.0 6.7 0.0 26.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.2 10.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.7 4.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.5 0.0 0.7 0.0 0.4 3.5 0.0 0.4 3.7 1.9 0.3 18.6 15.7 1.8 0.0 0.2 0.3 35.6 3.9 6.8 0.3 0.6 0.7 0.3 4.9 0.0 0.1 0.4 0.1 0.3 0.0 0.7 0.0 0.2 0.7 5.1 0.1 0.0 0.1 39.4 8.2 0.0 0.8 0.0 0.3 0.4 0.0 0.0 0.0 0.9 0.0 0.5 0.1 2.7 21.5 0.0 0.0 0.2 101.4 45.3 6.4 11.5 0.0 0.3 0.7 1.0 0.6 3.6 0.1 0.0 0.5 0.1 29.0 1.7 FUT7 ENSG00000180549 "Fucosyltransferase 7" Q11130 9 137030174-137032088 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 3.9;brain: 2.5;lymphoid tissue: 6.1" "Group enriched" "Detected in some" 8 "dendritic cells: 66.9;Langerhans cells: 38.7;monocytes: 20.7;NK-cells: 28.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 210.0" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "NB-4: 23.7;THP-1: 24.0;U-937: 14.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA042780 Approved "Golgi apparatus" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus" "HPA042780: AB_2678162" "unprognostic (1.33e-2)" "unprognostic (4.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (5.42e-2)" "unprognostic (5.01e-6)" "unprognostic (2.50e-1)" "unprognostic (2.35e-2)" "unprognostic (6.75e-4)" "unprognostic (4.68e-1)" "unprognostic (1.72e-2)" "unprognostic (3.20e-1)" "unprognostic (6.69e-6)" "unprognostic (3.99e-2)" "unprognostic (4.14e-2)" "unprognostic (1.03e-1)" "unprognostic (8.75e-2)" 0.3 0.1 0.6 1.7 1.7 3.9 0.1 1.0 1.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.1 0.7 1.2 0.1 0.1 0.9 4.6 1.9 1.2 0.0 0.0 0.0 0.2 0.1 1.1 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.4 0.1 0.7 6.1 0.3 0.2 1.2 1.0 0.2 0.4 3.2 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 23.7 0.0 0.2 0.0 1.2 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 2.0 7.5 1.5 10.4 1.6 52.5 20.1 52.1 28.9 21.7 5.5 0.9 4.3 91.6 127.1 0.2 210.0 90.2 15.4 0.6 1.7 1.0 1.3 0.7 1.2 1.9 1.2 1.1 0.7 1.2 2.5 0.1 0.0 0.0 0.0 3.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 66.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.2 0.0 3.7 38.7 0.0 0.0 2.7 0.0 0.0 20.7 0.0 28.8 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 4.6 0.0 0.7 0.0 FUZ "CPLANE3, FLJ22688, Fy" ENSG00000010361 "Fuzzy planar cell polarity protein" Q9BT04 19 49806866-49817376 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 78.7" "Group enriched" "Detected in many" 18 "Early spermatids: 1243.5;Late spermatids: 2329.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041779, HPA042196" Approved Approved Cytosol No NA "Cluster 5: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA041779: AB_10793974, HPA042196: AB_10797383" "unprognostic (2.40e-3)" "unprognostic (1.31e-1)" "unprognostic (7.73e-2)" "unprognostic (2.13e-1)" "unprognostic (1.49e-2)" "unprognostic (1.18e-2)" "unprognostic (4.36e-3)" "unprognostic (9.67e-2)" "unprognostic (1.47e-1)" "unprognostic (1.97e-2)" "unprognostic (1.06e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.50e-5)" "unprognostic (1.26e-2)" "unprognostic (2.03e-1)" "unprognostic (1.54e-1)" "unprognostic (1.70e-1)" 9.3 17.6 17.3 2.8 21.0 6.2 9.3 18.8 20.8 11.2 19.7 12.1 4.2 11.1 7.3 6.8 19.5 5.2 13.6 16.4 16.8 16.8 7.1 7.7 4.6 19.9 19.1 15.4 12.3 7.1 12.5 4.0 18.2 11.2 1.9 4.9 7.5 7.3 20.4 6.6 6.9 4.1 19.5 8.8 10.2 78.7 18.7 6.0 11.5 12.4 2.2 9.0 8.2 20.4 0.1 10.6 9.5 12.2 8.9 9.5 2.7 5.2 5.4 7.9 11.0 0.9 17.2 3.1 10.6 4.9 2.5 4.3 2.7 9.2 3.5 11.7 20.5 13.0 7.6 0.0 10.1 7.6 7.0 10.1 6.3 16.1 4.0 6.2 7.5 18.6 3.0 8.7 4.1 0.5 14.1 15.4 15.7 8.4 6.3 24.4 7.7 7.4 9.7 2.7 26.5 31.0 1.0 10.8 17.9 3.7 6.2 4.7 3.7 6.6 5.9 1.9 1.9 24.9 26.5 8.4 7.6 0.2 8.4 7.0 4.6 17.7 4.9 2.2 4.1 5.3 3.1 4.2 3.8 6.0 3.8 4.3 10.6 3.8 1.6 15.0 3.8 2.6 17.3 21.0 18.8 20.8 16.4 16.8 19.9 19.1 18.2 19.5 18.7 20.4 9.2 0.0 2.8 6.2 8.4 3.8 19.3 10.1 8.6 7.2 14.5 14.6 3.9 17.2 7.3 7.3 4.2 17.5 12.2 1.9 66.5 15.3 1243.5 61.6 8.0 6.5 2.4 19.3 2.7 5.1 12.1 11.1 6.1 8.1 10.2 11.5 13.6 5.8 13.2 10.1 3.0 3.5 12.2 7.1 7.6 2329.6 27.7 6.7 0.0 2.8 7.9 26.1 5.2 2.0 9.9 4.5 6.1 17.7 10.9 8.0 7.3 86.1 35.4 11.3 0.0 17.1 9.9 95.3 13.5 5.0 4.1 12.0 6.4 13.7 5.5 14.1 FXN "CyaY, FA, FARR, FRDA, X25" ENSG00000165060 Frataxin Q16595 9 69035751-69079076 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Heme biosynthesis, Ion transport, Iron storage, Iron transport, Transport" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022164, HPA068304" Supported Supported Mitochondria,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" Mitochondria Cytosol "CAB022164: , HPA068304: AB_2685970" "unprognostic (3.38e-2)" "unprognostic (1.54e-1)" "unprognostic (7.47e-2)" "unprognostic (2.37e-3)" "unprognostic (4.08e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (4.19e-2)" "unprognostic (2.53e-1)" "unprognostic (2.71e-3)" "unprognostic (1.10e-1)" "unprognostic (9.06e-2)" "unprognostic (1.67e-1)" "unprognostic (4.74e-2)" 10.3 20.1 8.9 7.8 9.2 29.1 10.1 9.7 8.9 9.3 11.7 10.4 7.4 12.1 12.1 9.5 10.2 5.3 27.0 9.0 10.4 12.9 46.3 7.1 9.8 9.8 10.2 17.6 15.1 22.2 8.1 9.1 9.8 10.2 12.3 4.1 11.7 13.6 25.5 5.2 7.7 13.3 9.5 12.6 10.1 10.7 9.9 5.4 10.4 19.8 10.4 12.3 7.9 10.4 27.0 22.1 34.2 17.0 15.7 23.1 34.3 18.6 16.3 28.0 21.2 11.8 16.6 45.9 14.0 19.5 28.8 28.6 41.8 42.6 34.9 53.9 47.5 66.2 14.1 87.2 26.7 48.7 27.7 25.7 33.7 27.8 29.9 9.6 37.7 28.0 50.3 43.9 26.1 25.6 14.0 21.0 47.5 53.1 42.8 32.7 24.0 32.0 32.2 21.5 26.9 12.1 19.2 12.5 20.7 24.3 14.1 14.4 22.7 18.0 32.0 24.1 27.6 11.6 11.4 27.8 8.5 39.7 18.5 8.1 39.9 0.4 48.6 45.4 37.5 36.3 48.0 48.4 42.8 22.7 61.6 59.8 1.9 60.8 36.2 33.2 43.3 49.5 8.9 9.2 9.7 8.9 9.0 10.4 9.8 10.2 9.8 9.5 9.9 10.4 11.0 3.2 11.5 13.1 19.9 9.7 19.8 36.6 14.8 6.8 16.9 20.8 38.2 10.0 10.5 14.7 4.2 39.9 14.9 4.9 21.5 17.5 2.4 11.7 22.5 16.9 7.2 56.1 14.2 14.7 22.3 14.7 14.3 8.7 7.0 15.4 11.0 69.0 33.4 0.0 18.6 15.3 18.3 22.1 16.1 6.3 15.8 13.9 17.8 9.4 18.3 7.6 28.8 6.6 10.8 15.0 3.7 13.2 42.0 17.1 5.8 27.2 7.4 1.6 13.1 10.1 19.8 5.1 32.3 29.8 8.1 14.6 17.1 27.9 17.5 14.1 FXYD3 "MAT-8, PLML" ENSG00000089356 "FXYD domain containing ion transport regulator 3" Q14802 19 35115879-35124324 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1800.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1870.8;Distal enterocytes: 5605.4;Intestinal goblet cells: 2165.8;Paneth cells: 3324.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 896.3;hTCEpi: 1603.2;OE19: 3112.0;RT4: 860.2;SK-BR-3: 830.8;WM-115: 589.7" HPA010856 Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" "unprognostic (2.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.37e-3)" "unprognostic (3.31e-3)" "unprognostic (6.38e-2)" "unprognostic (3.02e-1)" "unprognostic (2.64e-3)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.03e-1)" "unprognostic (2.32e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.15e-6)" "unprognostic (4.17e-2)" "unprognostic (2.08e-1)" "unprognostic (5.06e-2)" "unprognostic (7.69e-3)" 5.1 1.1 7.3 59.5 7.4 1.3 225.2 7.1 7.9 168.0 7.5 1466.2 102.7 13.2 15.2 685.3 104.3 100.5 5.8 7.1 6.5 12.0 2.0 150.2 0.8 8.0 7.3 1.8 64.3 0.1 24.7 84.9 6.8 512.1 1800.0 45.4 569.1 33.3 2.1 568.3 308.9 35.7 6.7 0.6 572.4 0.6 7.0 18.7 1.5 0.1 163.3 295.6 395.8 7.4 166.3 0.0 0.0 0.4 0.6 0.4 150.5 0.0 0.0 0.0 0.0 6.0 235.3 0.3 0.5 0.0 1.3 896.3 0.1 339.5 0.0 0.1 0.3 1.0 7.7 0.6 0.1 0.1 0.6 0.0 1603.2 0.0 0.7 0.1 0.1 0.1 0.1 1.1 0.0 304.5 0.8 2.2 0.8 3112.0 1.4 0.8 0.4 1.2 0.0 860.2 190.2 2.1 1.0 830.8 61.8 2.3 155.9 0.2 0.0 0.3 0.6 0.9 0.7 0.1 0.4 0.7 1.0 0.3 589.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 7.3 7.4 7.1 7.9 7.1 6.5 8.0 7.3 6.8 6.7 7.0 7.4 3.1 762.8 262.6 0.3 11.1 576.9 792.9 1870.8 340.4 2.9 557.5 515.7 1.3 201.6 1026.4 134.3 0.0 883.5 8.3 5605.4 1.9 35.6 0.4 180.1 29.5 19.7 974.3 2.7 0.1 708.4 138.1 20.3 356.8 194.1 22.3 0.0 0.0 0.9 81.4 1.7 0.0 2165.8 587.9 0.0 68.3 0.0 0.0 15.6 412.6 0.0 1.6 422.1 0.0 0.0 0.6 556.5 3324.0 0.0 6.5 1041.7 1693.0 0.5 1627.1 13.3 0.0 0.5 66.5 0.2 0.2 541.1 865.5 1512.1 17.9 0.0 1499.3 1509.9 FYTTD1 "DKFZp761B1514, UIF" ENSG00000122068 "Forty-two-three domain containing 1" Q96QD9 3 197737179-197787596 "Predicted intracellular proteins" "mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054474, HPA074880" Enhanced Supported "Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "HPA054474: , HPA074880: " "unprognostic (3.61e-2)" "unprognostic (6.01e-2)" "unprognostic (4.88e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.33e-2)" "unprognostic (3.80e-1)" "unprognostic (3.69e-2)" "unprognostic (9.57e-3)" "unprognostic (4.44e-2)" "unprognostic (1.66e-1)" "unprognostic (5.04e-3)" "unprognostic (8.74e-2)" "unprognostic (8.49e-3)" "unprognostic (3.40e-2)" "unprognostic (3.36e-1)" "unprognostic (3.29e-1)" "unprognostic (3.15e-1)" 29.7 20.9 12.1 27.1 12.6 39.2 26.6 16.1 14.6 24.8 9.1 19.9 16.7 30.4 19.6 43.9 19.1 24.4 41.3 12.1 14.9 25.7 28.9 23.6 32.4 12.4 13.9 27.5 36.4 28.7 12.6 33.5 13.0 25.1 21.6 33.8 18.2 28.8 92.6 27.1 19.3 34.9 12.8 26.3 18.2 41.1 13.3 34.1 29.6 67.0 37.7 33.6 16.9 14.9 104.5 22.6 43.7 41.7 50.1 55.3 13.4 50.0 50.8 75.4 61.4 35.3 34.8 66.4 177.1 59.3 40.0 36.7 55.5 51.0 79.8 14.5 24.9 99.8 32.9 16.1 48.9 75.1 46.5 40.0 64.6 40.8 58.3 52.1 60.4 36.8 45.9 139.0 67.6 86.9 82.2 18.1 9.6 45.1 41.2 74.9 53.6 47.4 54.8 67.3 82.4 35.7 76.8 60.0 56.4 31.8 141.2 39.1 54.0 38.5 38.1 49.0 53.6 83.5 137.2 79.3 40.8 106.4 40.6 59.2 26.9 26.5 32.4 31.8 40.7 20.0 30.7 35.9 29.9 18.9 33.4 32.2 8.5 64.6 31.0 16.9 30.2 45.7 12.1 12.6 16.1 14.6 12.1 14.9 12.4 13.9 13.0 12.8 13.3 14.9 60.6 35.3 27.2 14.7 78.5 82.3 46.6 24.3 42.7 35.1 47.0 34.4 109.7 25.8 30.1 47.8 31.3 24.4 63.9 19.0 90.1 35.5 21.7 27.3 58.9 55.2 56.4 25.2 23.7 36.1 27.5 53.7 30.1 42.6 66.6 29.4 36.4 50.7 38.0 45.4 19.6 23.7 28.5 48.6 67.8 18.3 32.0 54.8 51.6 22.5 108.6 41.8 82.4 19.6 23.0 34.3 16.5 37.2 65.4 74.5 17.1 51.1 44.6 45.2 39.5 45.8 63.1 96.3 90.7 54.0 91.1 50.1 60.7 51.9 20.0 63.6 G0S2 ENSG00000123689 "G0/G1 switch 2" P27469 1 209675412-209676390 "Metabolic proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 796.7;bone marrow: 1345.4" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 5188.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 44.5" "Immune cell enriched" "Detected in some" 60 "neutrophil: 549.5" "Lineage enriched" "Detected in many" 213 "granulocytes: 549.5" "Cell line enhanced" "Detected in many" "ASC diff: 460.8;HBEC3-KT: 726.2;PC-3: 180.6;RPMI-8226: 242.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "unprognostic (1.67e-3)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (3.82e-1)" "unprognostic (2.21e-1)" "unprognostic (5.04e-3)" "unprognostic (3.03e-1)" "unprognostic (1.38e-1)" "unprognostic (2.32e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (7.57e-3)" "unprognostic (1.53e-2)" "unprognostic (4.78e-2)" "unprognostic (2.64e-1)" 796.7 194.3 7.0 95.7 7.5 1345.4 519.5 7.4 44.5 9.2 8.2 20.9 7.6 34.3 11.7 8.6 26.8 15.7 175.9 8.8 6.8 262.6 664.6 318.4 7.6 7.4 8.6 47.5 31.0 0.8 9.5 13.8 9.1 38.3 4.0 0.6 59.8 14.8 651.4 24.3 31.7 10.9 7.9 49.3 63.8 30.1 7.8 5.9 23.7 303.4 5.4 136.2 17.3 9.7 0.0 4.3 0.0 0.0 460.8 16.1 0.3 0.7 1.4 1.9 1.8 19.3 14.8 0.0 4.1 3.4 2.5 0.0 0.0 726.2 4.4 0.7 1.2 0.0 1.5 0.6 37.5 0.2 0.1 47.8 1.6 32.4 0.0 15.8 0.0 0.0 0.2 0.0 0.2 0.0 0.2 15.7 1.3 0.0 180.6 0.0 0.0 242.8 1.7 0.3 0.9 1.4 16.3 0.0 4.0 0.0 0.2 56.7 73.6 0.0 4.9 0.2 0.1 0.0 1.1 0.1 13.1 0.1 0.0 0.0 1.0 9.1 0.0 1.1 0.4 0.1 2.5 0.1 0.3 0.3 0.0 0.0 549.5 0.0 0.2 0.0 0.0 0.4 7.0 7.5 7.4 44.5 8.8 6.8 7.4 8.6 9.1 7.9 7.8 9.7 52.3 9.6 59.5 5.9 16.1 232.4 654.8 760.7 124.1 0.6 295.2 43.3 359.1 14.3 111.6 11.0 0.0 1.8 5.0 16.6 299.3 52.3 25.3 42.7 12.0 264.5 29.3 6.9 0.9 148.2 3.6 730.2 11.7 112.0 39.1 34.7 12.1 179.4 174.2 0.0 3.1 32.6 22.4 78.2 5188.4 12.3 114.6 1060.3 327.3 2.8 30.7 23.1 1.0 11.1 0.9 736.5 42.9 71.5 10.3 416.7 41.1 304.9 42.3 0.3 32.9 56.4 60.1 52.1 1.1 35.2 161.4 4.2 33.3 7.5 52.5 513.7 GABBR1 "GPRC3A, hGB1a" ENSG00000204681 "Gamma-aminobutyric acid type B receptor subunit 1" Q9UBS5 6 29555629-29633976 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 150.5;Excitatory neurons: 58.7;Inhibitory neurons: 68.1;Oligodendrocyte precursor cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 6.3;HEL: 6.4;U-2 OS: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050483, HPA058459" Uncertain Approved Centrosome "Intracellular and membrane" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" Centrosome "HPA050483: AB_2681140, HPA058459: " "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (3.22e-3)" "unprognostic (2.93e-3)" "unprognostic (3.37e-1)" "unprognostic (2.65e-1)" "unprognostic (7.95e-4)" "unprognostic (5.44e-2)" "unprognostic (4.24e-2)" "unprognostic (1.14e-1)" "prognostic favorable (2.54e-5)" "unprognostic (1.23e-3)" "prognostic unfavorable (3.77e-10)" "unprognostic (3.82e-2)" "unprognostic (2.26e-1)" "unprognostic (3.87e-2)" "unprognostic (2.55e-2)" 20.4 18.0 10.2 2.4 10.9 2.8 20.7 6.4 9.6 45.3 0.0 33.6 0.2 42.8 0.0 14.5 39.0 0.9 28.4 3.9 0.0 16.9 4.7 20.6 2.0 0.3 2.0 40.7 10.4 1.1 30.8 1.3 0.0 34.3 0.5 0.5 16.3 4.2 6.1 19.2 20.2 1.4 0.0 39.0 18.5 7.9 6.1 0.2 22.8 0.0 1.2 25.3 31.6 0.0 2.4 0.0 1.5 6.3 0.7 1.6 1.6 1.6 0.7 1.4 0.4 1.9 0.1 1.1 1.5 0.0 0.3 2.0 0.7 0.0 0.0 5.9 2.6 6.4 3.7 0.0 0.9 0.2 3.1 0.0 0.0 1.2 0.0 1.8 0.8 3.3 5.5 0.0 0.2 1.5 0.6 0.1 0.4 0.0 0.9 2.9 0.6 0.1 0.2 0.0 0.4 1.0 0.4 0.0 2.6 0.4 1.2 0.9 3.6 2.5 6.2 0.2 3.1 5.4 0.6 0.0 1.4 2.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 10.2 10.9 6.4 9.6 3.9 0.0 0.3 2.0 0.0 0.0 6.1 0.0 16.8 12.8 20.2 150.5 10.6 11.9 6.2 4.7 10.2 30.6 13.4 17.7 13.9 1.5 10.7 3.7 0.0 0.3 5.7 0.8 0.0 1.4 4.7 1.3 30.6 17.0 7.2 5.7 58.7 0.9 0.2 16.0 1.5 1.9 7.6 14.6 22.5 0.3 1.1 23.5 68.1 4.7 2.0 5.9 18.3 3.1 15.2 14.4 0.0 19.7 11.0 9.8 0.0 72.4 16.3 1.7 1.6 25.6 0.7 7.6 0.1 1.0 1.1 17.3 13.1 12.5 18.8 1.2 2.7 5.3 11.1 0.5 5.9 6.7 1.5 2.8 GABRA1 EJM5 ENSG00000022355 "Gamma-aminobutyric acid type A receptor subunit alpha1" P14867 5 161847063-161899981 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "brain: 55.1;retina: 17.8" "Group enriched" "Detected in some" 11 "Bipolar cells: 198.0;Excitatory neurons: 220.5;Inhibitory neurons: 215.2" "Cancer enriched" "Detected in single" 5 "glioma: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022502, HPA029363, HPA055746" Enhanced Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Nucleoplasm "CAB022502: , HPA029363: , HPA055746: AB_2682904" "unprognostic (2.58e-2)" "unprognostic (4.78e-3)" "unprognostic (1.84e-1)" "unprognostic (3.31e-1)" "unprognostic (2.43e-1)" 0.0 1.2 6.7 0.0 11.1 0.0 0.0 24.8 55.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.7 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 14.3 0.6 0.0 0.0 0.2 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 11.1 24.8 55.1 7.7 21.7 0.0 0.0 0.0 0.0 14.3 24.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 198.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.1 0.0 0.0 220.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 215.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 17.8 0.0 3.5 0.0 8.0 16.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 9.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GABRA2 ENSG00000151834 "Gamma-aminobutyric acid type A receptor subunit alpha2" P47869 4 46243548-46475230 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 31.5;epididymis: 8.8" "Group enriched" "Detected in many" 5 "Astrocytes: 425.4;Excitatory neurons: 156.2;Inhibitory neurons: 111.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.6;glioma: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "U-2 OS: 4.2;U-87 MG: 2.1;WM-115: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029363, CAB079061" Supported Uncertain "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "CAB079061: , HPA029363: " "unprognostic (2.03e-2)" "unprognostic (2.77e-1)" "unprognostic (2.45e-4)" "unprognostic (6.87e-3)" "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.09e-1)" "unprognostic (6.90e-3)" "unprognostic (8.83e-2)" "unprognostic (2.22e-5)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" 1.2 0.3 20.2 0.4 29.9 0.2 1.3 2.6 31.5 0.5 0.0 3.0 0.9 0.4 8.8 0.7 0.0 0.5 0.2 29.4 16.0 6.3 0.4 0.1 0.3 0.3 1.9 0.7 0.1 0.0 0.5 0.4 0.0 0.1 2.1 2.4 0.2 0.7 0.1 0.2 6.0 0.2 1.3 1.2 0.5 0.5 13.8 0.4 0.1 0.1 0.4 0.2 0.7 8.8 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.4 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 4.2 0.2 0.0 0.2 0.6 0.0 2.1 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 29.9 2.6 31.5 29.4 16.0 0.3 1.9 0.0 1.3 13.8 8.8 4.9 0.0 0.0 425.4 0.0 0.1 0.0 0.0 1.2 15.3 0.2 0.0 0.6 0.0 0.0 40.5 4.2 0.0 0.0 23.1 3.9 0.0 9.1 1.2 31.7 1.0 31.8 0.0 156.2 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 111.6 3.4 0.0 0.0 0.0 17.1 0.6 0.1 1.8 16.9 0.0 0.2 0.0 13.0 5.5 0.0 4.7 0.0 0.0 0.0 38.1 0.1 0.0 1.1 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.0 0.1 0.0 2.7 0.0 GABRA5 ENSG00000186297 "Gamma-aminobutyric acid type A receptor subunit alpha5" P31644 15 26866911-26949208 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 111.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 27.6;Inhibitory neurons: 14.1" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Group enriched" "Detected in many" 4 "amygdala: 52.0;basal ganglia: 73.5;cerebral cortex: 98.6;hippocampal formation: 111.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "A549: 35.3;HAP1: 12.0;NTERA-2: 16.2;U-2 OS: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029363, HPA077031, CAB079022" Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "CAB079022: , HPA029363: , HPA077031: AB_2686825" "unprognostic (6.33e-2)" "unprognostic (8.94e-3)" "unprognostic (1.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-1)" "unprognostic (3.75e-1)" "unprognostic (9.50e-3)" "unprognostic (2.57e-1)" "unprognostic (7.63e-2)" "unprognostic (8.50e-2)" "unprognostic (1.44e-2)" 0.0 0.0 52.0 0.1 73.5 0.0 0.0 0.0 98.6 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.7 0.5 111.0 7.2 0.1 0.1 0.0 0.0 0.0 3.0 0.0 0.1 0.7 0.5 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 1.2 0.7 12.0 9.0 0.1 0.1 0.3 0.0 0.0 19.6 0.0 35.3 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 12.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.5 0.0 0.1 0.2 1.8 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.0 73.5 0.0 98.6 111.0 7.2 0.0 3.0 0.0 0.0 12.0 19.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.6 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.8 0.0 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GABRD ENSG00000187730 "Gamma-aminobutyric acid type A receptor subunit delta" O14764 1 2019329-2030758 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 49.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.7;Excitatory neurons: 30.0;Horizontal cells: 13.5;Inhibitory neurons: 37.4;Spermatogonia: 11.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.4;HMC-1: 1.2;MCF7: 4.4;NB-4: 2.7;SH-SY5Y: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044371 Enhanced Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 6: Brain - Smell perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA044371: AB_2678916" "unprognostic (4.28e-2)" "unprognostic (1.90e-1)" "unprognostic (5.95e-8)" "unprognostic (6.34e-3)" "unprognostic (2.66e-3)" "unprognostic (1.04e-2)" "unprognostic (3.44e-3)" "unprognostic (2.14e-1)" "unprognostic (4.53e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (4.12e-8)" "unprognostic (1.72e-1)" "unprognostic (1.76e-1)" "unprognostic (2.77e-1)" "unprognostic (5.16e-2)" 0.3 1.5 12.8 0.0 16.9 0.0 0.5 49.6 40.5 0.1 0.1 0.2 0.0 0.3 0.1 0.3 0.2 0.4 0.7 14.7 5.4 0.7 0.2 0.9 0.2 14.3 18.1 0.2 0.1 0.7 2.7 0.1 20.2 0.2 0.0 1.4 0.3 0.0 0.3 0.4 0.2 0.3 1.0 0.3 0.1 3.6 29.7 0.1 0.9 0.4 0.0 0.2 0.2 14.7 0.0 0.3 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 2.7 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.8 16.9 49.6 40.5 14.7 5.4 14.3 18.1 20.2 1.0 29.7 14.7 1.0 3.2 3.6 4.9 0.1 0.5 0.0 0.0 0.0 14.7 0.3 0.0 0.9 0.0 6.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 3.4 0.0 0.0 30.0 0.0 0.3 0.5 0.0 0.2 2.5 0.3 0.0 0.0 0.1 13.5 37.4 0.0 0.0 0.0 0.3 0.2 0.0 0.9 0.0 8.4 0.0 1.4 0.0 3.0 4.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 4.4 1.6 0.0 0.0 4.8 0.1 11.3 0.1 0.0 0.3 0.4 0.2 0.1 0.1 GABRG2 ENSG00000113327 "Gamma-aminobutyric acid type A receptor subunit gamma2" P18507 5 162000057-162162977 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 20.0;retina: 10.9" "Group enriched" "Detected in some" 7 "Bipolar cells: 119.0;Excitatory neurons: 239.9;Inhibitory neurons: 167.8" "Cancer enhanced" "Detected in single" "glioma: 1.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Group enriched" "Detected in many" 5 "B-cells: 1.6;granulocytes: 4.5;T-cells: 1.5" "Cell line enhanced" "Detected in many" "CACO-2: 10.3;Karpas-707: 10.2;RPMI-8226: 13.4;SuSa: 13.0;U-266/70: 20.1;U-266/84: 18.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079060 Supported NA NA "Cluster 6: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 16: U-266 - Nucleosome" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB079060: " "unprognostic (2.88e-2)" "unprognostic (1.56e-2)" "unprognostic (6.31e-3)" "unprognostic (3.07e-3)" "unprognostic (1.52e-1)" 0.3 4.7 7.9 0.4 9.0 2.2 0.1 7.2 20.0 0.0 0.0 0.7 1.2 0.3 0.4 0.4 0.5 2.6 0.8 9.6 10.6 0.2 0.4 0.9 0.4 4.7 4.6 0.7 0.1 0.0 1.1 1.9 10.7 0.1 0.5 10.9 0.5 0.1 0.5 2.2 0.9 0.8 0.5 0.4 1.9 0.7 9.3 1.7 0.5 0.5 0.5 0.2 0.0 7.5 3.9 1.7 2.3 0.2 0.0 0.1 1.9 0.7 0.0 0.0 0.0 10.3 5.5 0.5 5.9 0.0 0.2 1.1 1.6 0.0 0.0 1.0 1.0 0.0 1.7 1.2 0.0 0.0 0.6 0.4 0.3 0.0 0.0 0.1 0.0 1.0 2.4 10.2 0.0 2.8 0.5 0.1 7.4 3.1 3.6 0.5 0.1 13.4 0.0 3.1 1.1 0.9 0.3 0.5 4.1 13.0 6.7 6.9 0.1 0.3 5.2 0.4 0.5 20.1 18.7 0.1 0.1 0.5 0.3 4.5 0.1 0.3 0.2 0.1 1.2 1.6 0.3 0.3 0.0 1.4 1.5 0.3 0.7 0.4 0.1 0.3 0.4 0.1 7.9 9.0 7.2 20.0 9.6 10.6 4.7 4.6 10.7 0.5 9.3 7.5 0.0 19.2 23.5 15.3 0.0 0.0 0.0 0.0 0.0 119.0 0.1 0.0 0.4 0.0 10.5 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 239.9 0.0 0.1 1.4 0.0 0.0 8.8 0.0 0.0 0.0 0.1 16.8 167.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 12.2 0.0 2.6 0.0 12.1 15.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 6.6 9.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 GABRG3 ENSG00000182256 "Gamma-aminobutyric acid type A receptor subunit gamma3" Q99928 15 26971181-27541984 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 17.6;retina: 27.1;testis: 9.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 444.7;Inhibitory neurons: 615.5;Late spermatids: 351.0;Muller glia cells: 179.9" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Region enhanced" "Detected in many" "hypothalamus: 17.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 4.5;PC-3: 5.5;SK-MEL-30: 3.5;U-2 OS: 2.5;U-266/70: 3.2;U-87 MG: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054010 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA054010: AB_2682342" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (3.50e-2)" "unprognostic (2.61e-1)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (5.15e-2)" "unprognostic (2.95e-1)" "unprognostic (4.41e-1)" "unprognostic (1.43e-5)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" 0.0 0.4 3.5 0.2 3.0 0.0 0.4 0.0 4.2 0.8 0.0 0.0 0.0 0.1 1.9 0.0 0.4 0.0 0.0 0.9 17.6 0.7 0.1 0.0 0.6 0.5 0.2 0.0 0.0 0.0 3.0 0.0 0.0 6.6 0.0 27.1 0.8 0.2 0.0 0.3 0.0 0.0 0.6 1.0 0.0 9.3 10.2 1.0 1.5 0.0 0.8 0.0 0.2 2.9 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.4 0.3 0.0 5.5 0.0 0.0 1.0 0.0 0.0 0.1 1.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 3.2 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.0 0.0 4.2 0.9 17.6 0.5 0.2 0.0 0.6 10.2 2.9 0.1 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 4.6 2.5 1.4 0.9 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 86.2 3.2 0.1 0.3 0.0 0.0 444.7 0.0 0.0 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.1 0.0 615.5 0.0 0.0 0.0 0.0 351.0 0.9 0.2 0.0 7.5 0.0 179.9 0.0 16.1 7.9 0.0 0.0 0.7 0.0 3.1 0.0 0.3 0.0 4.6 0.0 0.1 0.1 1.6 7.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 GABRP ENSG00000094755 "Gamma-aminobutyric acid type A receptor subunit pi" O00591 5 170763350-170814047 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 152.3;esophagus: 171.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 169.0;Breast myoepithelial cells: 113.2;Club cells: 83.1;Endometrial ciliated cells: 146.0;Glandular and luminal cells: 464.0;Urothelial cells: 146.6" "Group enriched" "Detected in many" 4 "breast cancer: 35.4;cervical cancer: 49.3;endometrial cancer: 16.8;pancreatic cancer: 41.9;stomach cancer: 25.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.8" "Group enriched" "Detected in many" 8 "granulocytes: 11.8;monocytes: 5.7" "Cell line enhanced" "Detected in many" "A-431: 215.1;EFO-21: 236.8;HeLa: 166.8;PC-3: 331.3;SuSa: 418.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB014883 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "CAB014883: " "unprognostic (3.98e-3)" "prognostic favorable (3.37e-4)" "unprognostic (8.34e-2)" "unprognostic (1.57e-1)" "unprognostic (8.90e-2)" "unprognostic (1.27e-1)" "unprognostic (7.89e-2)" "unprognostic (4.97e-3)" "unprognostic (3.72e-1)" "unprognostic (4.93e-3)" "unprognostic (1.30e-3)" "unprognostic (2.30e-1)" "unprognostic (1.40e-2)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (5.92e-3)" "unprognostic (6.52e-3)" 4.5 3.6 10.4 7.3 10.5 9.9 152.3 15.8 16.2 13.1 5.4 4.2 15.4 48.6 19.0 171.5 12.9 27.3 5.4 7.6 23.0 6.1 7.1 14.7 5.7 12.5 6.1 3.9 23.8 2.0 2.0 9.1 10.6 12.7 4.9 42.1 35.8 16.6 13.7 19.0 16.2 2.6 2.7 7.4 27.4 8.3 10.4 4.7 6.1 2.7 42.2 5.4 29.4 17.9 215.1 9.9 10.1 7.0 0.7 4.3 23.8 3.8 1.5 0.5 0.6 38.1 23.6 3.3 236.8 1.1 2.3 75.7 6.4 0.5 0.6 3.5 7.6 14.1 166.8 5.7 0.8 5.1 11.2 1.6 3.0 2.8 1.8 8.0 1.4 13.4 57.6 26.5 0.4 6.7 9.5 4.7 84.5 3.7 331.3 13.7 6.6 8.2 13.8 11.6 8.2 4.0 76.5 3.9 2.2 418.8 4.2 2.4 8.8 19.1 69.3 15.7 15.7 10.0 6.7 6.3 2.6 13.9 2.9 11.8 1.9 6.1 0.4 1.5 1.1 0.3 0.4 0.3 0.6 0.7 0.5 0.5 4.5 0.2 5.7 0.9 0.6 2.3 10.4 10.5 15.8 16.2 7.6 23.0 12.5 6.1 10.6 2.7 10.4 17.9 1.1 3.2 0.6 0.0 0.9 0.0 14.9 44.4 0.0 0.0 169.0 113.2 0.7 51.5 83.1 1.8 0.0 5.2 2.3 0.0 0.0 10.4 0.0 146.0 48.8 3.8 0.0 0.0 0.3 13.8 0.6 2.4 2.0 464.0 0.0 0.0 0.0 0.1 2.3 0.0 0.2 0.3 12.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 56.6 0.1 0.0 0.0 24.2 0.1 0.1 34.0 0.0 0.0 0.2 5.9 0.0 0.0 4.5 0.0 5.7 2.7 0.0 0.6 146.6 GAK DNAJC26 ENSG00000178950 "Cyclin G associated kinase" O14976 4 849276-932373 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027405, HPA027459, HPA027463" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "HPA027405: AB_10611111, HPA027459: AB_10599948, HPA027463: AB_10601959" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.24e-3)" "unprognostic (1.07e-1)" "unprognostic (3.50e-3)" "unprognostic (1.68e-1)" "unprognostic (7.07e-2)" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (3.33e-3)" "prognostic favorable (1.70e-6)" "unprognostic (1.09e-3)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "prognostic favorable (7.41e-4)" 31.9 40.7 21.1 25.9 22.5 35.5 34.0 20.1 29.7 42.7 20.1 56.3 51.2 41.9 8.0 49.7 43.0 17.7 25.4 21.5 17.8 55.0 47.7 46.0 25.6 28.7 19.8 40.5 53.1 22.7 37.1 15.6 22.1 41.8 14.8 9.4 71.0 13.3 31.4 40.4 57.4 9.8 17.7 61.5 54.2 45.8 20.6 21.6 38.5 6.6 12.9 38.7 39.3 20.5 36.0 28.3 16.9 29.0 16.6 14.2 43.6 33.0 19.7 22.3 18.5 35.9 49.8 30.4 20.9 20.1 40.3 29.7 17.7 27.4 10.5 30.7 27.9 35.3 29.5 27.5 31.1 36.2 53.0 20.5 23.2 22.7 11.0 14.2 24.7 35.3 38.4 37.4 15.2 34.7 61.6 92.1 30.4 38.2 46.3 50.2 19.4 27.4 18.2 28.8 29.0 31.3 19.3 24.2 23.3 14.1 39.2 30.7 40.8 30.9 18.0 31.8 45.1 59.5 41.3 33.8 34.9 43.7 29.0 3.0 10.3 12.8 8.8 9.8 7.6 4.9 5.8 6.1 6.5 3.9 3.3 4.8 7.4 4.8 24.6 7.6 5.6 9.4 21.1 22.5 20.1 29.7 21.5 17.8 28.7 19.8 22.1 17.7 20.6 20.5 24.7 25.6 33.2 34.0 33.9 17.0 15.3 17.9 14.8 27.2 25.3 17.7 12.2 18.6 28.2 25.8 64.6 19.0 46.2 131.3 9.8 18.8 99.1 32.2 21.6 26.7 29.4 26.1 25.7 28.0 17.5 19.5 93.8 52.5 18.3 31.2 18.5 31.6 36.6 11.8 23.5 66.5 26.4 35.9 18.4 134.7 25.1 35.5 16.0 59.0 28.8 16.3 35.0 9.0 24.4 37.6 71.1 18.8 26.1 28.4 65.8 31.0 33.8 26.9 19.7 17.9 18.0 32.9 27.4 19.9 22.3 31.1 34.6 41.6 65.0 44.6 GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "brain: 645.9;pituitary gland: 885.8" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 22.2;Ductal cells: 38.9;Endometrial ciliated cells: 64.2;Endometrial stromal cells: 50.8;Exocrine glandular cells: 52.1;Extravillous trophoblasts: 48.7;Glandular and luminal cells: 26.4;Pancreatic endocrine cells: 39.5;Prostatic glandular cells: 82.5;Urothelial cells: 24.3" "Cancer enhanced" "Detected in many" "testis cancer: 22.2" "Region enriched" "Detected in many" 13 "hypothalamus: 645.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 267.2;HEK 293: 119.3;K-562: 139.5;NB-4: 493.5;SH-SY5Y: 189.6" "Region enhanced" "Detected in many" "hypothalamus: 82.6" "Low region specificity" "Detected in all" "HPA049864, CAB079779" Enhanced Supported Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 60000 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 24: NB-4 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" Vesicles "CAB079779: , HPA049864: AB_2680922" "unprognostic (8.56e-2)" "unprognostic (1.45e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (8.07e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.98e-2)" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-2)" 3.2 0.9 2.8 14.9 2.1 0.7 4.4 1.1 5.2 1.0 0.8 17.6 1.8 0.2 0.0 0.8 1.0 0.2 1.0 2.2 645.9 1.5 0.3 0.5 0.1 48.5 5.1 0.2 2.1 0.1 885.8 0.3 13.8 4.4 4.0 0.0 0.9 0.2 0.4 33.3 4.1 9.9 0.6 0.3 9.7 1.0 19.5 0.7 0.4 0.0 0.0 0.7 2.9 2.6 0.0 11.0 1.1 0.3 0.0 0.0 24.0 36.7 0.0 0.7 0.0 267.2 9.9 0.0 12.7 1.3 0.4 0.1 0.0 0.2 0.0 0.0 119.3 6.4 74.6 0.0 1.3 3.7 0.0 1.7 4.0 0.0 0.1 0.0 6.3 0.0 139.5 0.0 0.2 77.2 0.0 493.5 60.3 2.9 23.7 0.0 0.1 51.1 0.6 0.0 49.8 189.6 25.8 1.5 0.0 26.8 1.5 57.6 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.1 1.1 5.2 2.2 645.9 48.5 5.1 13.8 0.6 19.5 2.6 0.6 0.0 0.0 0.0 0.2 2.0 22.2 0.1 0.0 0.0 3.2 5.8 1.4 0.0 0.0 0.0 0.0 0.6 0.1 0.7 0.0 38.9 0.1 64.2 50.8 3.4 1.8 4.2 2.1 52.1 48.7 6.6 2.0 26.4 4.5 0.4 0.0 0.0 2.0 0.0 0.2 1.1 4.1 0.0 1.2 0.2 0.0 0.7 1.8 0.0 0.6 0.0 0.0 0.0 0.3 39.5 0.1 0.0 1.0 82.5 0.0 0.4 0.0 0.0 0.0 1.6 6.7 2.2 10.9 1.1 3.4 1.9 0.8 0.0 1.3 24.3 GAL3ST1 CST ENSG00000128242 "Galactose-3-O-sulfotransferase 1" Q99999 22 30554635-30574665 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.6;intestine: 24.4;kidney: 18.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Muller glia cells: 35.3;Oligodendrocyte precursor cells: 26.7;Oligodendrocytes: 53.6;Proximal enterocytes: 48.1;Proximal tubular cells: 24.6" "Cancer enriched" "Detected in many" 6 "renal cancer: 38.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 27.6;CACO-2: 7.7;EFO-21: 14.6;K-562: 6.6;OE19: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001220, HPA077138" Approved Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles Nucleoplasm "HPA001220: AB_1078933, HPA077138: " "unprognostic (2.69e-2)" "unprognostic (3.12e-4)" "unprognostic (5.93e-2)" "unprognostic (1.08e-2)" "unprognostic (2.32e-1)" "unprognostic (6.50e-3)" "unprognostic (1.53e-2)" "unprognostic (2.23e-1)" "unprognostic (2.89e-1)" "unprognostic (5.18e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (2.33e-1)" "unprognostic (4.23e-2)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" 1.3 0.2 14.8 0.4 33.3 0.8 1.1 27.7 25.8 2.7 0.3 5.2 23.0 2.4 1.7 0.5 3.1 5.2 1.1 14.6 18.3 18.4 4.0 1.9 0.7 32.9 29.0 2.3 6.9 0.7 1.5 0.9 31.0 3.1 2.4 2.3 0.5 1.4 3.1 1.6 24.4 0.3 23.2 0.3 8.2 5.0 29.1 0.1 0.2 0.3 0.0 1.6 1.8 51.6 0.0 27.6 0.5 0.2 0.0 0.0 2.0 0.0 0.2 0.0 0.0 7.7 3.8 0.4 14.6 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.7 0.4 0.4 5.7 0.6 0.2 0.2 0.2 0.0 0.1 0.2 0.0 0.0 0.4 6.6 0.6 0.0 0.2 0.3 1.1 3.9 10.6 0.4 0.2 0.0 0.7 1.1 0.1 0.3 1.8 0.0 0.4 0.2 0.7 0.2 0.2 0.8 0.2 0.2 0.3 0.0 2.4 1.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.0 0.3 0.1 0.1 0.5 0.0 0.0 0.6 0.0 0.0 14.8 33.3 27.7 25.8 14.6 18.3 32.9 29.0 31.0 23.2 29.1 51.6 0.5 0.0 0.0 2.3 0.3 0.4 0.1 0.0 0.0 0.8 0.6 3.3 0.6 30.0 0.0 3.7 0.0 0.1 0.0 14.0 15.6 7.0 1.1 1.1 0.3 0.3 10.9 2.7 2.0 11.1 0.1 0.3 5.1 2.4 0.0 0.9 0.0 1.6 0.1 0.0 1.9 5.7 0.0 0.3 0.3 0.8 1.5 0.2 0.0 0.0 0.0 35.3 0.0 26.7 53.6 5.0 8.8 2.2 0.1 0.4 48.1 24.6 0.1 1.3 0.0 2.1 0.3 12.4 14.3 0.0 0.3 0.3 0.2 0.0 7.6 0.1 GAL3ST2 GP3ST ENSG00000154252 "Galactose-3-O-sulfotransferase 2" Q9H3Q3 2 241776822-241804287 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "intestine: 9.4" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Oligodendrocyte precursor cells: 1.0" "Group enriched" "Detected in many" 6 "colorectal cancer: 6.7;ovarian cancer: 4.9;stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Hep G2: 3.7;HMC-1: 10.5" "Not detected" "Not detected" HPA071809 Enhanced "Intracellular and membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA071809: AB_2686450" "unprognostic (5.22e-3)" "unprognostic (6.52e-2)" "unprognostic (1.85e-2)" "unprognostic (4.04e-3)" "unprognostic (3.04e-4)" "unprognostic (3.45e-2)" "unprognostic (2.48e-2)" "unprognostic (2.87e-1)" "unprognostic (4.13e-2)" "unprognostic (2.25e-3)" "unprognostic (2.58e-1)" "unprognostic (4.99e-2)" "unprognostic (2.87e-11)" "unprognostic (4.32e-2)" "unprognostic (1.55e-1)" "unprognostic (5.99e-3)" "unprognostic (3.49e-1)" 0.5 0.3 0.4 0.8 0.3 0.2 0.0 0.0 0.6 0.5 0.0 9.4 0.0 0.1 0.0 0.0 0.5 0.4 0.1 0.2 0.3 0.3 0.5 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 3.7 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 3.7 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.6 0.2 0.3 0.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 GAL3ST3 GAL3ST2 ENSG00000175229 "Galactose-3-O-sulfotransferase 3" Q96A11 11 66040765-66049161 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.7;thyroid gland: 17.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.9;Cardiomyocytes: 3.6;Cone photoreceptor cells: 10.4;Excitatory neurons: 3.7;Horizontal cells: 5.0;Inhibitory neurons: 4.7;Oligodendrocyte precursor cells: 7.5;Rod photoreceptor cells: 15.4" "Group enriched" "Detected in many" 5 "glioma: 4.7;ovarian cancer: 5.5;thyroid cancer: 10.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "NTERA-2: 6.5;SH-SY5Y: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" "prognostic unfavorable (6.53e-6)" "unprognostic (1.24e-1)" "unprognostic (3.30e-1)" "unprognostic (1.57e-2)" "unprognostic (2.62e-1)" "unprognostic (6.08e-2)" "unprognostic (2.01e-3)" "unprognostic (7.26e-2)" "unprognostic (2.07e-2)" "unprognostic (1.40e-1)" "unprognostic (5.29e-1)" 0.0 0.0 5.3 0.0 7.7 0.0 0.0 4.8 5.7 2.9 0.1 0.0 0.0 3.9 0.1 0.0 2.6 0.0 7.1 4.8 2.1 5.3 0.0 0.0 0.0 2.0 2.6 0.2 0.6 0.3 4.1 0.0 1.6 0.8 0.0 5.7 0.0 1.6 0.3 0.1 0.0 2.8 1.5 0.0 0.0 2.1 2.8 0.0 17.1 0.3 0.0 0.0 0.3 3.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.7 4.8 5.7 4.8 2.1 2.0 2.6 1.6 1.5 2.8 3.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 3.6 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 7.5 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 15.4 0.0 0.0 0.3 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GALC ENSG00000054983 Galactosylceramidase P54803 14 87837820-87993665 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism, Sphingolipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 68.4;Kupffer cells: 72.1;Late spermatids: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 84.3;HMC-1: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022196 Approved "Intracellular and membrane" NA NA 53000 "Cluster 2: Granulocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB022196: " "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (9.39e-2)" "unprognostic (3.08e-1)" "unprognostic (9.70e-2)" "unprognostic (1.73e-1)" "unprognostic (6.56e-2)" "unprognostic (8.44e-3)" "unprognostic (8.08e-2)" "unprognostic (1.84e-2)" "unprognostic (6.00e-2)" "unprognostic (2.13e-1)" "unprognostic (6.80e-2)" "unprognostic (2.72e-2)" 15.0 17.2 20.0 14.9 23.3 23.2 13.3 22.1 26.1 12.0 20.8 15.1 33.3 11.1 12.2 6.6 20.7 18.4 13.5 18.5 21.6 21.3 12.1 23.9 11.7 23.0 22.6 15.8 10.8 9.4 9.8 16.8 23.9 14.3 17.3 18.4 8.1 9.3 8.0 9.1 34.4 9.6 22.3 15.4 16.4 24.0 20.8 9.7 24.5 12.9 7.9 13.6 7.5 30.6 0.0 19.5 7.2 0.0 23.8 21.3 0.0 9.1 17.9 8.3 9.9 10.8 84.3 5.3 26.4 8.7 0.0 1.3 0.0 1.0 10.2 2.7 0.6 29.8 0.7 0.0 19.5 0.1 78.4 20.7 6.6 5.6 0.0 3.4 22.6 0.0 10.0 3.9 14.4 1.9 0.0 4.5 6.5 35.4 2.2 0.0 0.5 0.3 13.4 7.8 6.7 15.6 24.6 4.0 0.2 17.2 20.4 20.5 19.7 0.0 12.9 5.6 0.2 4.2 8.0 0.0 2.3 6.8 19.2 25.3 15.2 34.2 11.1 16.6 24.0 2.5 8.3 10.8 8.9 1.2 6.0 7.0 11.9 16.3 13.4 1.6 5.3 11.7 20.0 23.3 22.1 26.1 18.5 21.6 23.0 22.6 23.9 22.3 20.8 30.6 11.3 25.6 19.0 26.8 8.0 8.4 5.6 9.4 3.4 10.1 9.1 5.2 9.2 10.0 8.9 14.7 12.5 6.2 27.6 15.3 3.9 9.8 51.6 17.3 10.9 11.4 6.1 13.7 17.8 11.4 12.7 15.2 7.7 5.8 68.4 15.9 18.2 6.1 26.6 3.3 21.2 10.2 4.1 72.1 11.8 77.9 16.1 25.0 10.6 8.4 26.7 7.3 40.2 33.2 42.6 14.1 20.0 10.1 9.3 6.1 15.9 6.7 22.1 10.4 0.0 9.8 10.6 14.9 10.0 3.5 11.5 6.6 21.2 12.9 16.7 7.9 GALNS "GALNAC6S, GAS" ENSG00000141012 "Galactosamine (N-acetyl)-6-sulfatase" P34059 16 88813734-88856970 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Dwarfism, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 51.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 11.3;granulocytes: 31.3;monocytes: 17.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026404, HPA042433, HPA074225" Supported Approved Cytosol "Intracellular and membrane" NA NA 2000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "CAB026404: , HPA042433: AB_2732499, HPA074225: " "unprognostic (3.16e-1)" "unprognostic (9.98e-2)" "unprognostic (4.03e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (3.66e-4)" "unprognostic (4.15e-3)" "unprognostic (1.32e-1)" "unprognostic (4.84e-3)" "unprognostic (2.00e-1)" "unprognostic (3.53e-2)" "unprognostic (4.12e-3)" "unprognostic (4.24e-2)" "unprognostic (5.54e-2)" "unprognostic (3.59e-2)" "unprognostic (6.84e-2)" 9.2 12.8 9.4 9.3 10.0 22.2 6.3 10.0 11.5 9.1 22.1 10.0 10.6 7.4 14.5 8.8 11.4 9.7 11.0 10.6 12.0 8.6 8.1 10.4 7.4 12.6 16.4 6.7 5.0 8.6 11.9 8.6 12.0 7.7 6.1 3.3 8.3 4.7 6.4 8.4 10.6 7.1 10.8 9.1 8.1 26.3 11.3 4.8 9.1 3.6 5.6 9.0 9.1 12.0 5.7 42.7 6.2 43.4 47.1 22.4 41.9 17.9 27.3 19.1 14.7 22.7 36.8 7.1 37.1 29.2 28.8 33.0 9.0 14.2 11.4 4.7 13.8 4.5 17.0 13.2 31.5 3.6 28.5 31.4 26.9 21.4 6.0 27.0 16.4 7.8 9.9 4.1 11.3 33.3 9.2 15.0 14.2 14.3 19.6 19.6 5.4 12.1 11.9 13.2 15.8 12.2 42.4 4.0 21.9 14.4 27.3 32.5 31.3 41.8 31.5 43.2 10.0 4.3 4.5 12.6 45.2 29.7 25.4 1.4 17.4 31.3 4.5 12.5 3.9 3.0 2.5 4.0 11.3 1.3 2.5 3.1 21.7 4.0 9.6 4.7 4.6 8.5 9.4 10.0 10.0 11.5 10.6 12.0 12.6 16.4 12.0 10.8 11.3 12.0 4.8 16.0 4.8 9.4 5.9 6.5 7.3 27.7 9.1 5.0 6.8 5.0 8.4 4.3 11.0 3.7 6.2 9.9 8.5 16.8 3.9 5.7 21.0 27.2 9.6 7.2 12.0 1.3 7.6 3.7 14.0 13.8 6.1 8.9 1.3 11.9 7.5 6.4 18.7 25.2 10.4 6.8 8.2 13.2 6.3 37.3 7.2 11.3 7.2 2.8 18.2 8.8 14.4 4.0 9.8 5.6 13.6 6.8 9.9 6.7 17.3 5.9 35.1 10.0 6.6 9.4 9.0 51.3 42.8 6.3 5.7 15.9 7.9 16.5 10.1 6.8 GALNT1 GalNAc-T1 ENSG00000141429 "Polypeptide N-acetylgalactosaminyltransferase 1" Q10472 18 35581117-35711834 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 331.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012628 Uncertain "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA012628: AB_1849439" "unprognostic (9.81e-2)" "unprognostic (1.01e-1)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" "unprognostic (2.08e-1)" "unprognostic (2.83e-2)" "unprognostic (1.96e-2)" "unprognostic (7.06e-2)" "unprognostic (2.03e-2)" "unprognostic (1.51e-2)" "unprognostic (3.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (4.38e-2)" "unprognostic (2.74e-2)" "unprognostic (1.07e-2)" "unprognostic (8.60e-2)" 28.9 20.6 11.9 27.4 12.1 26.0 37.2 12.3 14.2 26.5 15.1 42.8 42.9 19.4 19.7 57.6 15.9 28.9 23.8 10.9 14.4 17.4 45.9 23.3 33.5 13.1 13.2 16.9 24.6 12.2 13.5 52.0 13.5 25.4 41.1 17.1 46.8 18.0 29.0 52.4 49.3 22.7 13.1 25.4 27.1 16.9 13.1 18.6 30.0 37.3 40.8 70.5 27.0 13.9 32.5 34.9 40.5 37.6 78.5 74.0 53.4 33.2 35.4 30.3 27.4 21.0 61.9 38.3 34.9 36.0 28.7 24.4 20.2 63.8 48.1 45.0 18.5 48.7 62.8 48.8 39.2 106.6 62.1 50.7 59.7 47.6 52.1 90.1 331.4 30.8 14.8 49.3 118.9 26.1 31.6 40.5 41.6 33.5 16.4 38.9 53.0 18.5 124.8 148.9 21.8 42.9 59.4 43.0 36.2 77.1 32.9 82.8 116.3 55.7 22.5 37.0 37.1 70.1 35.7 72.5 39.1 72.1 29.5 7.2 3.4 7.6 3.2 4.5 3.6 4.1 2.2 2.9 4.0 2.4 2.0 3.0 4.3 4.6 6.6 4.4 2.5 1.4 11.9 12.1 12.3 14.2 10.9 14.4 13.1 13.2 13.5 13.1 13.1 13.9 85.6 80.1 44.1 35.9 33.4 29.8 28.4 28.8 22.2 31.3 77.2 43.8 43.3 48.6 39.9 16.5 12.5 31.0 44.8 109.1 7.9 42.6 1.4 77.6 44.7 41.7 38.9 30.9 57.5 39.9 92.7 49.8 26.0 73.0 20.3 51.7 35.7 71.3 77.9 85.8 56.3 59.0 16.2 58.8 37.1 2.9 19.0 56.7 19.6 57.1 41.3 105.9 28.8 54.3 56.8 58.5 51.4 18.0 36.7 54.4 76.8 22.0 33.5 28.5 13.1 55.2 28.7 6.5 12.2 26.3 82.1 33.2 33.7 50.3 85.3 52.8 GALNT10 GalNAc-T10 ENSG00000164574 "Polypeptide N-acetylgalactosaminyltransferase 10" Q86SR1 5 154190730-154420984 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 65.8" "Cell type enhanced" "Detected in many" "Microglial cells: 74.0;Oligodendrocyte precursor cells: 156.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 284.9;TIME: 161.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007525 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1100000 "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA007525: AB_1849443" "unprognostic (6.99e-2)" "unprognostic (4.33e-2)" "unprognostic (9.85e-2)" "prognostic favorable (3.33e-6)" "unprognostic (1.63e-1)" "unprognostic (6.98e-2)" "unprognostic (6.95e-3)" "unprognostic (2.38e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (5.69e-4)" "unprognostic (2.88e-3)" "unprognostic (2.63e-1)" "unprognostic (1.54e-1)" "unprognostic (7.76e-3)" "unprognostic (1.22e-1)" "unprognostic (1.61e-2)" "unprognostic (3.08e-1)" 12.1 15.6 10.7 14.4 14.5 19.3 13.5 12.1 10.0 24.1 33.0 16.1 14.4 6.3 6.0 4.9 14.6 16.7 9.0 9.5 12.5 9.7 4.4 15.5 9.9 16.1 13.9 65.8 9.8 13.6 11.5 4.7 12.3 9.1 14.7 7.8 13.5 3.7 5.4 6.0 12.6 11.6 9.9 15.8 22.0 4.5 13.9 7.8 16.6 8.2 9.4 11.1 5.2 12.6 25.6 85.3 20.3 17.8 42.2 37.3 15.6 71.7 39.9 27.9 26.7 12.1 56.7 16.6 49.3 121.4 49.9 4.4 9.4 56.0 25.4 43.2 6.7 45.4 16.0 16.5 32.4 9.9 42.3 46.7 12.9 22.7 33.2 284.9 54.4 12.5 10.5 50.9 48.4 26.4 1.1 6.8 8.0 71.1 17.3 5.1 10.7 16.6 38.6 17.1 2.7 6.6 31.8 117.0 9.4 29.6 45.6 7.4 161.2 67.5 15.9 16.8 77.7 14.5 15.0 8.7 44.2 19.3 21.1 2.0 1.2 2.4 3.1 1.6 2.8 1.9 1.8 2.0 1.4 2.1 0.8 2.1 2.5 1.9 1.8 1.1 1.6 1.0 10.7 14.5 12.1 10.0 9.5 12.5 16.1 13.9 12.3 9.9 13.9 12.6 17.4 9.6 46.4 32.7 17.4 4.8 3.9 5.6 1.8 4.6 12.4 8.6 5.0 5.7 8.7 14.7 4.2 0.7 27.7 23.0 9.8 9.1 10.3 12.4 7.4 14.1 3.0 21.4 14.3 30.1 1.5 13.7 30.5 22.3 10.2 10.5 23.9 5.3 8.5 0.0 15.9 20.4 6.1 19.5 7.8 22.5 38.2 12.4 0.0 74.0 11.9 17.4 44.3 156.9 66.9 36.8 13.6 50.0 15.4 8.2 15.3 2.7 0.7 10.5 6.6 5.6 7.8 2.0 4.0 1.2 3.7 0.8 21.7 27.3 12.2 4.2 GALNT12 GalNAc-T12 ENSG00000119514 "Polypeptide N-acetylgalactosaminyltransferase 12" Q8IXK2 9 98807670-98850081 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 74.7;intestine: 55.8;stomach 1: 54.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.2;Intestinal goblet cells: 142.4;Undifferentiated cells: 42.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 128.4;U-2197: 160.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA048292, HPA071076" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA048292: AB_2680343, HPA071076: " "unprognostic (7.85e-3)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (1.47e-2)" "unprognostic (2.97e-3)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.03e-2)" "unprognostic (1.97e-1)" "unprognostic (2.61e-2)" "unprognostic (7.71e-2)" "prognostic favorable (3.24e-4)" "unprognostic (9.05e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-3)" "unprognostic (6.87e-2)" 5.0 2.0 1.2 7.7 1.3 2.2 3.4 6.5 1.8 8.7 4.3 55.3 34.2 3.7 74.7 19.6 7.5 10.5 1.2 1.1 1.4 4.8 0.4 11.7 3.2 2.6 1.4 0.4 13.6 6.3 3.4 2.6 2.7 4.6 55.8 0.6 25.5 4.3 1.3 3.4 27.1 14.0 1.1 2.2 54.8 4.6 1.5 3.3 14.7 0.6 6.1 11.9 4.6 1.6 5.4 4.1 3.4 13.5 10.0 7.8 0.0 1.4 2.1 2.0 4.6 0.8 21.6 0.0 5.0 0.9 12.2 38.0 2.9 1.3 1.6 26.2 1.7 2.4 0.2 0.0 0.5 1.6 0.5 3.8 0.9 6.4 0.0 2.7 2.3 19.3 30.2 0.0 0.6 13.9 2.6 4.7 16.7 128.4 5.6 6.5 0.3 0.1 2.3 7.7 12.4 1.1 0.5 30.6 3.0 7.7 4.5 4.5 4.3 0.0 0.3 160.9 0.0 2.1 4.8 2.3 37.1 0.0 0.9 0.0 0.0 0.5 0.3 0.0 0.6 0.0 0.4 0.2 0.0 0.1 0.6 0.3 0.0 0.6 0.0 0.1 0.0 0.1 1.2 1.3 6.5 1.8 1.1 1.4 2.6 1.4 2.7 1.1 1.5 1.6 1.3 3.2 25.7 2.0 2.3 2.4 1.3 8.3 1.2 2.4 0.4 0.1 1.0 18.6 16.9 11.0 16.7 1.0 2.6 101.2 0.0 11.2 1.8 4.8 1.6 1.6 19.9 1.3 7.4 25.4 1.7 12.5 32.1 8.7 2.5 2.4 0.0 0.0 2.3 0.0 5.7 142.4 2.0 0.3 3.9 1.4 2.1 3.9 0.0 3.7 0.2 0.8 3.1 3.5 7.0 32.0 36.5 7.5 1.7 7.4 21.9 2.7 16.9 0.2 0.0 0.7 1.5 5.9 10.5 9.9 1.3 1.1 4.5 5.1 42.5 11.1 GALNT13 "GalNAc-T13, KIAA1918" ENSG00000144278 "Polypeptide N-acetylgalactosaminyltransferase 13" Q8IUC8 2 153871922-154453979 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;retina: 9.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 214.6;Inhibitory neurons: 333.1;Oligodendrocyte precursor cells: 986.7;Oligodendrocytes: 398.2" "Cancer enriched" "Detected in some" 5 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 43.8;U-251 MG: 12.0;WM-115: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060775 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA060775: AB_2684358" "unprognostic (1.97e-1)" "unprognostic (3.43e-3)" "unprognostic (2.47e-2)" "unprognostic (1.00e-3)" "unprognostic (4.21e-3)" "unprognostic (7.73e-3)" "unprognostic (6.50e-2)" "unprognostic (8.17e-2)" "unprognostic (3.57e-1)" "unprognostic (9.15e-2)" "unprognostic (3.83e-2)" "unprognostic (3.09e-2)" "unprognostic (5.17e-2)" "unprognostic (2.05e-5)" "unprognostic (8.61e-3)" "unprognostic (1.52e-1)" "unprognostic (2.05e-1)" 2.1 5.0 8.4 0.2 9.9 0.1 1.2 30.1 7.7 1.7 1.0 0.4 0.2 1.8 1.2 0.1 0.4 0.5 0.2 7.6 17.9 0.1 0.0 2.1 0.0 9.3 12.3 0.5 0.3 0.0 1.7 0.4 11.4 2.0 0.3 9.9 4.1 1.4 1.0 0.6 0.3 1.0 9.5 0.0 0.4 0.6 10.8 0.0 0.0 0.0 0.0 0.7 0.2 11.4 0.0 5.2 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.1 5.5 0.0 0.0 0.1 2.8 0.0 5.0 1.8 0.0 0.0 0.0 0.1 0.2 0.0 0.0 8.6 0.0 0.1 0.1 0.5 1.0 0.0 0.0 0.2 7.3 0.2 6.9 0.0 0.3 1.0 0.0 0.0 7.5 43.8 0.1 0.1 0.0 0.7 0.0 0.1 0.0 0.1 1.9 0.1 12.0 0.6 0.1 0.0 7.2 0.0 33.5 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 9.9 30.1 7.7 7.6 17.9 9.3 12.3 11.4 9.5 10.8 11.4 0.2 25.6 1.1 13.1 0.0 0.1 0.0 0.0 0.0 14.4 0.2 0.3 1.0 0.0 1.3 0.0 52.1 0.1 0.0 0.1 0.0 0.0 1.9 0.4 21.5 0.7 3.5 0.0 214.6 0.2 0.0 2.8 0.0 0.3 0.0 0.1 0.0 0.0 0.1 72.3 333.1 1.3 0.0 0.0 0.0 1.1 0.0 0.1 0.0 2.8 0.0 0.9 0.0 986.7 398.2 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.0 1.6 0.0 0.2 0.5 0.8 0.6 0.0 0.1 0.0 0.2 4.2 0.9 0.0 GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174680-16231992 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 157.4;brain: 141.7" "Cell type enhanced" "Detected in many" "Adipocytes: 103.9;Astrocytes: 34.6;Early spermatids: 26.6;Endothelial cells: 26.9;Hepatic stellate cells: 41.7;Muller glia cells: 47.4;Oligodendrocytes: 69.3" "Cancer enriched" "Detected in many" 5 "glioma: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "ASC diff: 133.0;ASC TERT1: 128.8;HSkMC: 102.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 40000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Cytosol "HPA017076: AB_1849458" "unprognostic (3.87e-1)" "unprognostic (4.84e-4)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (7.40e-4)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (8.28e-6)" "unprognostic (5.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-3)" "unprognostic (1.88e-1)" "unprognostic (8.51e-2)" "unprognostic (1.78e-3)" 157.4 4.9 45.1 1.7 55.8 2.7 87.2 62.5 49.3 12.3 14.4 21.7 3.0 11.4 11.9 12.4 24.9 5.6 18.1 47.9 90.8 11.8 4.0 9.4 4.1 137.6 60.4 22.3 3.6 2.4 3.5 32.3 130.8 6.0 3.9 13.4 25.5 4.7 36.3 41.7 21.2 7.0 102.4 12.3 15.3 9.1 62.8 4.0 18.3 35.3 1.3 33.0 22.8 141.7 0.4 1.3 0.9 1.0 133.0 128.8 0.3 3.4 2.5 0.4 1.3 0.0 0.5 0.5 1.9 7.8 2.3 0.8 0.5 1.4 2.0 0.6 1.4 1.1 1.9 0.0 7.4 1.5 0.4 102.8 0.0 1.2 1.8 2.4 2.8 0.7 0.2 3.0 1.1 1.9 0.0 2.1 0.5 0.8 1.1 0.3 1.1 24.1 0.5 0.5 0.4 0.3 0.4 1.0 0.6 0.6 0.7 1.8 3.9 0.6 4.3 26.8 0.6 1.4 5.1 1.4 2.5 0.4 0.4 0.5 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 45.1 55.8 62.5 49.3 47.9 90.8 137.6 60.4 130.8 102.4 62.8 141.7 103.9 0.0 1.7 34.6 0.1 0.5 0.4 0.0 0.0 3.8 1.1 0.9 2.8 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 26.6 0.5 3.3 26.9 0.0 0.0 4.9 0.0 0.1 24.7 0.0 1.0 1.3 0.1 41.7 1.8 0.1 0.0 3.9 0.0 0.0 0.8 2.1 16.7 1.8 0.5 0.0 22.5 0.1 47.4 0.0 5.0 69.3 0.2 0.0 0.7 1.8 2.1 0.0 0.1 0.0 3.2 0.0 7.3 2.1 25.5 0.5 0.1 0.9 0.0 0.2 0.3 0.0 0.3 GALNT16 "GalNAc-T16, GALNTL1, KIAA1130" ENSG00000100626 "Polypeptide N-acetylgalactosaminyltransferase 16" Q8N428 14 69259277-69357033 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.8;heart muscle: 45.0" "Cell type enhanced" "Detected in many" "Astrocytes: 16.6;Cardiomyocytes: 46.7;Excitatory neurons: 27.6;Fibroblasts: 24.0;Inhibitory neurons: 23.8;Smooth muscle cells: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.5;ASC diff: 11.7;hTEC/SVTERT24-B: 17.0;hTERT-RPE1: 17.2;SCLC-21H: 8.7;U-2 OS: 19.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059136, HPA075325" Approved Approved Vesicles,Cytosol NA NA 370000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA059136: AB_2683919, HPA075325: " "unprognostic (9.71e-3)" "unprognostic (7.47e-2)" "unprognostic (4.02e-1)" "unprognostic (2.30e-2)" "unprognostic (6.71e-2)" "unprognostic (5.72e-3)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-4)" "unprognostic (1.31e-2)" "prognostic favorable (5.23e-6)" "unprognostic (5.38e-3)" "unprognostic (3.34e-2)" "unprognostic (3.93e-2)" "unprognostic (7.96e-5)" 14.4 11.6 25.7 2.0 24.4 0.1 12.0 14.7 28.4 7.6 6.5 6.5 2.2 7.3 2.8 3.6 5.6 3.4 45.0 27.0 35.5 7.7 2.0 3.4 3.2 19.6 22.5 2.1 4.3 2.5 4.7 0.4 19.9 4.0 2.2 1.3 23.5 4.6 4.4 7.5 3.7 8.6 16.4 12.1 3.2 3.5 40.8 2.2 4.9 5.8 1.3 3.1 5.0 21.3 0.0 0.8 8.5 0.3 11.7 5.3 0.0 1.3 0.1 1.5 2.3 0.4 0.0 0.0 0.2 1.4 0.8 0.0 3.0 0.0 0.3 0.1 6.0 0.0 0.2 0.5 0.1 0.0 0.5 0.5 0.0 17.0 0.0 17.2 0.9 0.0 0.0 0.0 2.8 0.5 0.0 0.0 1.7 0.0 0.1 0.0 4.8 0.0 0.5 0.0 8.7 3.0 1.8 0.4 0.0 0.3 0.3 0.0 0.1 1.7 19.9 2.2 2.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 24.4 14.7 28.4 27.0 35.5 19.6 22.5 19.9 16.4 40.8 21.3 4.0 0.0 0.0 16.6 0.0 4.1 0.4 0.0 0.0 2.8 3.1 3.0 46.7 0.0 0.0 0.0 2.1 0.1 0.2 0.0 3.9 0.1 9.7 0.2 0.4 1.7 0.0 0.0 27.6 0.0 0.0 24.0 0.5 0.2 0.0 0.3 0.0 0.0 0.2 0.0 23.8 0.1 0.0 0.0 6.1 11.2 0.9 0.3 3.6 5.6 0.0 0.1 0.0 8.0 1.6 0.0 0.0 3.8 0.0 0.5 0.1 0.1 0.0 0.8 6.6 10.1 14.8 0.6 2.1 0.3 3.3 0.0 0.3 11.2 0.6 0.4 GALNT2 GalNAc-T2 ENSG00000143641 "Polypeptide N-acetylgalactosaminyltransferase 2" Q10471 1 230057990-230282122 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 133.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 429.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011222 Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA 13000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA011222: AB_1849446" "unprognostic (1.26e-1)" "prognostic unfavorable (1.22e-6)" "unprognostic (1.15e-2)" "unprognostic (1.35e-2)" "unprognostic (8.70e-3)" "unprognostic (7.77e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (8.48e-8)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (1.70e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (2.79e-13)" "unprognostic (3.79e-3)" "unprognostic (1.49e-1)" "unprognostic (3.64e-2)" "unprognostic (1.89e-1)" 32.9 49.6 17.0 34.8 19.9 13.9 21.9 15.2 16.7 24.7 22.0 28.9 19.5 27.1 6.9 21.0 22.4 21.2 27.4 15.8 18.6 18.5 100.1 27.1 14.0 23.0 19.5 39.2 68.1 9.9 13.6 27.6 18.3 21.4 12.4 19.8 22.1 14.3 67.4 14.7 23.6 25.0 15.3 17.4 33.1 19.7 25.1 42.8 19.0 27.4 11.2 33.4 19.5 15.5 79.5 103.7 59.9 71.4 112.4 95.3 122.8 146.3 90.0 58.4 55.6 45.2 146.5 20.0 106.2 77.7 135.9 150.7 39.9 123.0 48.6 200.1 52.0 60.7 217.2 50.9 60.9 23.4 114.8 136.9 59.8 78.0 30.9 127.3 69.2 110.1 77.0 29.6 65.6 21.8 122.3 23.9 82.1 52.8 97.7 134.3 85.5 61.7 57.4 92.9 18.9 70.1 148.4 7.9 91.0 31.7 46.5 43.5 165.3 56.7 107.9 129.5 118.0 97.9 60.3 44.4 146.1 46.3 429.7 1.5 10.7 3.6 4.4 9.3 3.2 3.4 2.6 4.5 7.8 5.8 2.5 5.0 3.2 2.8 10.2 13.2 3.3 7.7 17.0 19.9 15.2 16.7 15.8 18.6 23.0 19.5 18.3 15.3 25.1 15.5 18.6 16.0 21.3 71.5 32.1 15.3 20.0 52.8 20.5 30.8 13.8 10.7 13.6 18.6 30.1 23.9 33.3 7.3 21.7 24.1 5.9 49.7 47.2 18.7 15.4 17.9 16.8 27.6 67.3 133.0 123.4 36.1 21.4 24.5 13.3 20.5 19.6 98.8 24.9 28.6 82.0 18.9 4.1 42.4 9.7 24.6 35.8 28.9 24.9 106.8 44.0 10.9 18.6 72.9 44.6 88.5 21.6 29.3 109.0 23.5 17.9 19.2 23.5 73.5 13.1 33.1 25.4 3.4 14.0 16.6 8.0 16.6 21.2 32.8 17.6 29.9 GALNT3 "GalNAc-T3, HFTC, HHS" ENSG00000115339 "Polypeptide N-acetylgalactosaminyltransferase 3" Q14435 2 165747588-165794659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 77.3" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 152.8;Pancreatic endocrine cells: 188.1;Prostatic glandular cells: 155.7;Urothelial cells: 274.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 50.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.4;HaCaT: 108.3;HBEC3-KT: 69.2;hTCEpi: 88.2;OE19: 201.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007613 Enhanced Supported "Golgi apparatus" NA NA 440000 "Cluster 46: Basophils - DNA binding" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA007613: AB_1078941" "unprognostic (1.95e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.16e-3)" "unprognostic (2.78e-1)" "unprognostic (3.22e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (4.13e-2)" "unprognostic (4.47e-2)" "unprognostic (2.74e-1)" "unprognostic (6.44e-2)" "unprognostic (3.62e-3)" "unprognostic (1.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.79e-2)" "unprognostic (3.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-1)" 1.5 1.7 1.7 8.4 2.1 54.0 26.0 2.7 1.8 29.3 4.3 48.9 43.5 5.2 9.3 27.4 38.8 32.2 0.6 1.8 3.4 10.9 2.4 14.0 3.7 4.5 5.2 6.8 26.2 6.9 9.8 6.4 3.3 25.2 53.2 3.7 55.3 8.2 0.3 15.3 39.5 2.5 7.0 20.1 77.3 25.8 1.9 3.3 25.4 0.4 12.3 17.3 12.6 5.4 61.5 0.0 0.6 0.2 0.1 2.6 43.0 18.3 7.7 6.6 16.0 32.0 85.4 0.4 0.1 0.0 0.1 108.3 0.0 69.2 13.5 1.3 13.0 0.0 14.9 0.3 0.3 14.5 0.4 0.5 88.2 0.0 30.3 2.1 0.1 2.9 0.0 55.0 5.0 42.7 0.5 5.6 0.1 201.1 7.8 0.2 0.0 1.7 17.8 42.0 6.5 0.1 0.3 49.6 16.8 1.9 21.7 0.9 0.5 0.1 1.0 0.1 0.3 34.4 16.3 1.3 0.2 14.0 0.6 50.5 6.8 32.2 10.2 9.0 7.5 6.6 3.1 5.8 11.4 6.0 1.0 3.4 25.2 10.6 13.8 17.3 5.6 6.2 1.7 2.1 2.7 1.8 1.8 3.4 4.5 5.2 3.3 7.0 1.9 5.4 1.0 12.8 34.4 7.8 13.6 38.0 107.9 36.5 29.6 0.6 45.0 26.8 0.4 35.8 45.9 66.2 0.0 8.5 37.7 68.6 3.9 70.2 127.5 91.8 5.2 2.9 23.4 1.3 10.5 113.2 22.5 2.3 102.4 70.5 45.7 0.7 1.1 0.6 8.2 0.0 5.1 152.8 28.5 1.9 12.4 14.1 2.5 8.3 16.0 1.0 7.5 16.1 15.5 27.6 1.4 188.1 46.5 0.4 29.7 155.7 32.6 3.1 89.3 1.0 6.6 0.6 4.3 71.5 1.1 42.4 41.3 11.2 14.4 1.2 61.8 274.4 GALNT6 GalNAc-T6 ENSG00000139629 "Polypeptide N-acetylgalactosaminyltransferase 6" Q8NCL4 12 51351247-51392867 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 62.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 49.2;Gastric mucus-secreting cells: 130.5;granulocytes: 164.5;Oligodendrocytes: 57.6" "Cancer enhanced" "Detected in many" "breast cancer: 31.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 29.1" "Group enriched" "Detected in all" 4 "granulocytes: 29.1;monocytes: 9.7;NK-cells: 15.5" "Cell line enhanced" "Detected in many" "BJ hTERT+: 107.0;CACO-2: 104.1;OE19: 97.6;SK-BR-3: 110.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA011762, HPA017086" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" NA NA 4800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Golgi apparatus" "HPA011762: AB_1849450, HPA017086: AB_1849452" "unprognostic (2.03e-1)" "unprognostic (6.65e-2)" "unprognostic (2.26e-2)" "prognostic favorable (9.85e-4)" "unprognostic (1.35e-2)" "unprognostic (1.18e-1)" "unprognostic (7.15e-3)" "unprognostic (2.05e-1)" "unprognostic (2.27e-2)" "prognostic favorable (5.40e-4)" "unprognostic (1.88e-2)" "unprognostic (5.25e-2)" "unprognostic (7.13e-4)" "unprognostic (5.65e-3)" "unprognostic (3.18e-1)" "unprognostic (2.16e-2)" "unprognostic (1.18e-2)" 1.7 3.1 3.3 8.0 11.8 9.6 18.1 7.2 9.1 32.2 0.2 6.7 21.2 1.3 24.7 2.4 6.5 2.4 0.4 4.2 7.3 2.9 1.2 5.7 7.2 8.8 11.1 0.9 8.3 1.4 1.1 9.6 10.8 0.9 6.9 0.1 31.0 3.2 0.4 5.6 21.6 1.6 5.2 8.2 62.6 0.6 9.7 6.8 2.5 0.1 5.9 3.7 1.8 18.1 39.0 4.1 0.7 0.1 0.0 0.6 59.8 63.0 107.0 25.4 17.0 104.1 19.0 0.5 5.8 34.4 0.0 35.9 1.5 27.3 17.1 8.3 4.1 24.6 0.7 0.8 1.0 13.6 82.2 2.3 25.2 23.1 23.0 0.2 65.7 14.2 5.4 1.0 0.1 73.7 43.2 10.1 5.3 97.6 66.6 0.2 0.1 10.3 21.3 2.2 0.5 23.5 0.4 110.5 0.1 12.2 59.3 5.9 75.7 0.2 12.9 0.2 0.3 2.1 0.5 3.6 7.2 29.5 0.2 7.1 5.8 29.1 3.8 5.2 1.6 1.2 2.2 3.1 4.5 3.3 3.4 2.9 1.1 15.5 9.7 4.1 1.7 3.2 3.3 11.8 7.2 9.1 4.2 7.3 8.8 11.1 10.8 5.2 9.7 18.1 0.8 3.2 2.4 0.3 11.8 2.9 3.8 5.8 5.7 0.4 38.9 18.4 1.3 1.5 15.6 1.8 0.0 14.1 11.3 12.4 3.9 2.6 2.0 3.5 0.3 4.1 0.0 15.3 1.0 10.9 49.2 1.6 130.5 5.8 164.5 3.8 1.4 0.3 14.4 0.0 0.5 17.4 2.0 16.3 10.3 1.5 0.0 15.1 1.8 1.0 7.2 0.2 9.2 0.0 57.6 24.3 33.9 0.4 5.5 7.6 39.6 2.0 12.4 0.0 0.0 1.5 1.5 0.4 1.6 2.6 9.2 4.8 14.9 1.8 11.8 5.8 GALNT7 GALNAC-T7 ENSG00000109586 "Polypeptide N-acetylgalactosaminyltransferase 7" Q86SF2 4 173168811-173323967 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 143.4;Inhibitory neurons: 172.0;Intestinal goblet cells: 126.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064243, HPA065317" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 6200000 "Cluster 5: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" Nucleoplasm "HPA064243: AB_2685223, HPA065317: AB_2685465" "unprognostic (1.81e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.53e-4)" "unprognostic (1.37e-3)" "unprognostic (1.48e-1)" "unprognostic (6.86e-3)" "unprognostic (2.72e-2)" "unprognostic (1.77e-1)" "unprognostic (2.85e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (7.65e-4)" "unprognostic (1.33e-1)" "unprognostic (4.66e-3)" "unprognostic (3.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.34e-3)" "unprognostic (5.97e-2)" 6.4 6.4 6.4 16.3 8.8 11.5 23.3 34.2 8.3 25.1 3.5 47.8 29.1 16.9 7.0 14.9 9.8 15.6 5.9 6.6 7.8 7.8 2.9 9.6 12.2 12.6 8.3 11.2 22.2 8.7 5.2 13.0 11.7 39.7 52.8 22.4 27.4 8.1 1.4 3.9 33.7 16.7 10.1 11.0 65.7 11.9 8.4 60.0 13.5 3.9 9.8 17.0 5.9 16.0 71.1 37.2 35.0 11.2 18.6 27.1 50.3 18.1 20.5 16.7 23.0 11.5 109.9 39.4 13.3 16.6 45.2 59.2 15.0 32.0 22.7 154.3 29.1 47.8 72.2 0.4 12.2 71.6 32.8 17.5 28.3 37.6 18.9 63.4 112.3 28.2 32.6 59.3 86.0 23.5 52.7 39.4 34.8 70.2 24.0 52.1 32.4 10.2 123.2 32.8 28.2 21.5 8.5 50.4 25.4 45.3 20.2 21.0 135.6 11.9 52.3 0.6 40.0 17.2 0.2 20.8 48.6 42.3 43.6 13.2 14.3 18.9 5.1 7.5 7.2 6.2 5.7 5.3 12.4 3.3 4.4 3.3 21.3 7.5 8.0 5.0 9.2 6.4 6.4 8.8 34.2 8.3 6.6 7.8 12.6 8.3 11.7 10.1 8.4 16.0 10.0 6.4 38.0 72.8 12.1 1.8 9.0 12.3 4.0 47.9 41.1 19.8 9.6 8.6 36.0 20.2 2.1 1.4 16.4 143.4 0.0 14.4 2.5 28.3 13.3 11.3 22.8 12.0 74.4 48.9 3.7 12.1 102.4 52.9 24.1 14.8 12.1 0.2 10.3 10.1 172.0 126.8 24.4 17.9 6.2 4.2 9.3 17.2 8.8 62.8 16.3 8.1 5.2 71.4 54.1 39.9 50.0 5.3 6.6 52.8 63.7 10.0 17.4 25.5 13.1 16.1 11.7 3.8 5.5 14.9 1.1 0.8 9.9 13.1 48.6 19.4 GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" Q9NY28 12 4720400-4851927 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 31.3;testis: 13.5" "Group enriched" "Detected in some" 6 "Early spermatids: 95.2;Intestinal goblet cells: 47.0;Late spermatids: 150.2" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.2;glioma: 1.8;pancreatic cancer: 0.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 23.4;U-266/84: 7.6" "Not detected" "Not detected" "HPA012638, HPA073461" Supported Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA No "Cluster 22: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA012638: AB_2294503, HPA073461: AB_2686604" "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (1.75e-2)" "unprognostic (6.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (5.76e-2)" "unprognostic (8.06e-5)" "unprognostic (1.16e-2)" "unprognostic (6.67e-5)" "unprognostic (5.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-2)" 0.4 0.6 3.2 1.8 3.3 0.0 0.6 2.7 5.1 0.5 2.0 14.0 5.7 0.3 0.1 0.1 0.6 0.0 2.5 3.2 2.8 0.4 0.2 0.3 0.2 3.4 3.2 0.7 0.2 0.0 2.8 0.1 3.3 0.4 31.3 0.2 0.4 0.3 0.1 0.2 12.6 0.8 2.9 0.5 0.5 13.5 3.3 0.0 0.2 0.0 0.0 0.4 0.3 4.1 0.0 0.0 0.5 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 23.4 0.0 0.0 0.0 0.1 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 3.2 3.3 2.7 5.1 3.2 2.8 3.4 3.2 3.3 2.9 3.3 4.1 0.1 6.4 0.5 1.3 0.5 0.0 0.0 0.1 0.6 2.1 0.1 2.3 4.5 0.0 0.0 0.0 0.0 0.0 1.5 1.8 0.0 0.0 95.2 0.5 0.1 0.5 6.6 0.0 1.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 47.0 0.0 0.0 0.0 150.2 1.5 0.1 0.0 3.7 0.2 0.5 0.0 15.1 7.4 0.2 0.6 2.6 0.0 0.1 1.0 1.0 0.0 0.6 6.6 0.7 0.1 12.3 8.3 0.0 0.0 0.0 0.8 0.3 2.2 0.0 GALNTL6 "GalNAc-T6L, GALNT17" ENSG00000174473 "Polypeptide N-acetylgalactosaminyltransferase like 6" Q49A17 4 171812254-173041559 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 7.8;lymphoid tissue: 2.5" "Group enriched" "Detected in some" 17 "Excitatory neurons: 424.4;Inhibitory neurons: 1567.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.6" "Lineage enriched" "Detected in single" 8 "B-cells: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031019 Uncertain "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA031019: AB_10601653" "unprognostic (6.84e-2)" "unprognostic (1.28e-1)" "unprognostic (2.01e-2)" "unprognostic (5.73e-2)" "unprognostic (7.50e-2)" "unprognostic (8.32e-2)" "unprognostic (3.25e-1)" "unprognostic (9.55e-2)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.06e-1)" "unprognostic (2.80e-1)" "unprognostic (1.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.11e-2)" "unprognostic (4.84e-3)" "unprognostic (1.73e-2)" 0.0 0.2 3.6 0.4 2.8 0.4 0.2 0.5 4.0 1.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.1 6.0 7.8 0.0 0.1 0.1 0.3 0.2 5.3 0.0 0.1 0.0 0.0 0.0 2.3 0.7 0.2 1.3 0.3 0.0 0.3 0.1 0.5 0.0 1.1 2.5 1.0 2.4 4.0 0.0 0.1 1.4 0.1 0.1 0.4 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.5 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 2.8 0.5 4.0 6.0 7.8 0.2 5.3 2.3 1.1 4.0 0.6 0.0 0.0 1.5 10.4 2.4 0.3 0.1 0.0 0.0 1.6 0.3 0.0 1.2 0.0 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 13.5 0.0 0.0 0.1 0.0 0.0 424.4 4.1 0.0 0.3 2.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 1567.9 2.6 0.0 1.6 0.0 21.1 0.3 0.9 5.4 13.1 0.0 0.1 0.0 57.3 9.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 1.2 0.2 1.6 1.6 0.0 0.3 0.0 0.0 0.1 0.4 0.1 GALP ENSG00000197487 "Galanin like peptide" Q9UBC7 19 56176008-56185775 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Hormone, Neuropeptide" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 1.8;Glandular and luminal cells: 1.0" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053938 Uncertain "Secreted in brain" NA NA "Cluster 49: Ciliated cells - Cilium organization" "HPA053938: AB_2682315" "unprognostic (8.51e-3)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (7.02e-2)" 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 GANAB "G2AN, GIIA, GluII, KIAA0088" ENSG00000089597 "Glucosidase II alpha subunit" Q14697 11 62624826-62646726 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026874, HPA061426" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 23000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA026874: AB_1849745, HPA061426: AB_2684516" "unprognostic (2.12e-1)" "unprognostic (5.95e-3)" "unprognostic (4.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-2)" "unprognostic (3.65e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (5.80e-3)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-3)" "unprognostic (5.91e-2)" "unprognostic (1.01e-3)" "unprognostic (3.81e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.54e-4)" 93.9 73.7 31.8 88.2 34.5 83.7 92.8 36.6 36.7 112.6 51.6 104.7 95.6 102.1 151.7 66.4 106.9 75.3 67.9 31.7 41.2 98.5 171.7 86.8 81.7 38.5 34.9 115.5 88.1 130.6 21.8 141.8 38.1 97.5 116.8 79.4 101.8 111.1 39.4 74.7 90.5 126.0 36.5 86.7 85.2 66.1 39.8 105.2 132.6 53.0 94.8 90.7 34.2 43.4 298.2 245.9 318.2 552.0 464.1 389.0 332.9 312.4 480.4 436.2 362.1 222.2 515.9 201.2 616.0 572.5 337.8 376.4 375.2 376.7 443.8 155.8 191.3 202.9 317.8 125.6 389.0 325.7 248.7 397.2 248.4 433.6 475.3 533.0 422.3 199.6 278.5 352.9 398.2 313.6 167.6 193.4 262.3 236.6 237.7 209.5 368.7 513.1 285.7 230.3 168.6 221.2 451.1 308.2 370.8 321.6 380.9 304.8 311.6 430.0 272.2 342.9 309.9 360.8 423.8 152.2 473.9 173.1 421.7 23.9 19.3 19.1 23.8 23.4 23.1 15.9 17.2 20.0 20.8 14.9 20.9 21.3 8.9 29.8 22.2 18.4 17.3 22.6 31.8 34.5 36.6 36.7 31.7 41.2 38.5 34.9 38.1 36.5 39.8 43.4 42.7 12.8 20.7 17.3 29.8 28.3 29.4 45.8 13.6 31.4 57.4 53.8 7.8 52.9 24.2 68.0 60.5 81.7 33.4 40.1 5.9 47.0 18.5 31.4 59.1 42.2 31.8 25.0 12.6 42.6 137.3 45.9 27.5 46.5 11.4 72.8 48.2 98.0 57.9 35.3 16.0 48.9 34.6 45.8 25.1 16.4 58.4 32.7 35.6 15.9 38.9 36.5 38.1 11.1 16.5 39.5 29.3 68.1 50.4 34.0 47.8 27.0 26.3 41.4 32.9 36.4 34.7 25.3 47.4 21.2 31.3 80.2 25.2 63.1 56.3 32.4 GAPT "C5orf29, FLJ33641" ENSG00000175857 "GRB2 binding adaptor protein, transmembrane" Q8N292 5 58491435-58497090 "Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 16.9;lymphoid tissue: 42.7" "Cell type enhanced" "Detected in some" "B-cells: 84.8;dendritic cells: 160.1;granulocytes: 55.0;Macrophages: 43.0;monocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "eosinophil: 1000.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 1000.3" "Cell line enhanced" "Detected in some" "HEL: 71.5;HL-60: 41.8;NB-4: 43.3;THP-1: 33.7;U-937: 118.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011048, HPA011070" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA011048: , HPA011070: AB_1848887" "unprognostic (9.79e-2)" "unprognostic (5.67e-3)" "unprognostic (2.39e-2)" "unprognostic (3.26e-2)" "unprognostic (3.36e-2)" "unprognostic (8.09e-4)" "unprognostic (4.32e-1)" "unprognostic (1.23e-3)" "unprognostic (4.14e-2)" "unprognostic (9.47e-3)" "unprognostic (7.28e-2)" "unprognostic (2.93e-1)" "unprognostic (3.52e-3)" "unprognostic (3.74e-2)" "unprognostic (2.42e-2)" "unprognostic (2.33e-2)" "unprognostic (1.40e-2)" 1.7 0.8 0.7 28.5 0.7 16.9 2.3 0.7 1.1 2.7 1.3 2.7 3.7 1.3 1.1 2.1 1.6 5.7 0.7 0.7 1.0 0.8 2.0 4.2 25.3 1.3 1.1 0.4 1.1 1.1 0.6 1.0 1.3 1.8 3.8 0.5 1.9 1.2 0.2 0.8 6.6 4.7 1.0 18.2 3.7 0.7 1.1 6.9 0.6 0.7 42.7 6.0 0.5 1.8 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 71.5 0.2 0.0 0.0 41.8 12.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 43.3 0.0 0.0 0.0 17.7 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 33.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 118.4 0.0 125.5 66.7 1000.3 0.4 46.5 0.5 97.0 0.4 0.4 76.8 97.4 0.3 0.3 82.0 1.4 59.3 205.4 0.3 32.0 0.7 0.7 0.7 1.1 0.7 1.0 1.3 1.1 1.3 1.0 1.1 1.8 0.4 3.2 1.9 0.0 84.8 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.2 0.0 0.6 0.0 0.0 0.0 160.1 0.0 0.0 0.0 1.6 0.0 0.1 0.9 0.0 8.8 0.0 0.0 0.1 0.4 0.5 0.0 55.0 0.0 0.4 0.0 14.3 0.0 0.0 0.0 0.0 19.4 6.0 0.5 0.0 43.0 0.0 1.9 41.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 GARNL3 "bA356B19.1, DKFZp761J1523" ENSG00000136895 "GTPase activating Rap/RanGAP domain like 3" Q5VVW2 9 127224265-127393660 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 77.1;Excitatory neurons: 178.4;Inhibitory neurons: 184.7;Microglial cells: 48.7;Oligodendrocyte precursor cells: 45.2;Oligodendrocytes: 165.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "OE19: 5.3;SH-SY5Y: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028757, HPA074886" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 21: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoplasm "HPA028757: AB_2294383, HPA074886: AB_2732270" "unprognostic (3.15e-2)" "unprognostic (7.19e-2)" "unprognostic (2.25e-2)" "unprognostic (3.40e-2)" "unprognostic (3.12e-2)" "unprognostic (1.19e-3)" "unprognostic (5.58e-3)" "unprognostic (3.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.24e-3)" "unprognostic (6.88e-4)" "unprognostic (2.22e-1)" "unprognostic (3.23e-7)" "unprognostic (6.39e-2)" "unprognostic (6.60e-2)" "unprognostic (7.04e-3)" "unprognostic (1.78e-5)" 3.1 6.0 5.7 0.3 5.7 0.0 4.4 11.6 6.0 6.0 2.0 2.9 1.8 7.4 5.2 4.4 5.4 3.7 11.3 6.9 5.2 2.1 1.8 2.4 1.3 4.7 4.5 4.5 2.1 6.6 2.0 1.4 5.8 6.2 1.9 1.3 5.0 4.0 1.5 2.8 1.8 6.7 4.6 1.8 1.8 2.9 4.2 0.6 5.7 1.8 1.3 4.6 3.3 11.2 0.5 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.3 0.1 1.0 1.2 0.3 0.0 1.0 0.1 0.4 0.6 1.8 0.0 0.1 0.0 0.8 0.0 1.9 1.2 0.4 0.4 0.1 0.1 1.5 0.0 0.0 1.5 0.7 1.9 0.8 0.7 0.1 0.5 0.0 0.3 0.4 5.3 1.6 0.1 1.1 3.4 1.9 2.5 1.2 3.9 0.8 2.7 0.4 0.6 0.9 0.0 0.0 0.2 1.0 0.0 0.4 2.3 2.4 1.0 0.4 0.5 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 5.7 5.7 11.6 6.0 6.9 5.2 4.7 4.5 5.8 4.6 4.2 11.2 1.3 0.0 0.0 77.1 0.5 2.7 1.7 0.4 2.8 8.0 3.1 4.3 6.8 4.3 2.0 3.7 0.0 0.6 0.2 0.9 1.9 0.3 2.2 1.0 21.1 1.5 1.2 0.4 178.4 0.6 0.1 4.8 5.6 1.2 0.0 2.4 1.8 2.5 0.8 1.7 184.7 0.8 0.0 1.3 1.9 1.0 7.5 1.3 1.8 48.7 0.0 4.0 0.0 45.2 165.3 0.4 1.6 3.4 0.5 3.3 0.6 1.8 0.1 1.0 0.0 7.1 4.0 3.5 3.9 2.7 2.0 0.3 0.7 1.0 0.8 1.2 GARS1 "CMT2D, DSMAV, GARS, GlyRS, SMAD1" ENSG00000106105 "Glycyl-tRNA synthetase 1" P41250 7 30580533-30634033 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Hydrolase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 34.1;Cytotrophoblasts: 47.0;Extravillous trophoblasts: 70.0;Hofbauer cells: 44.3;Syncytiotrophoblasts: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017896, HPA019097" Enhanced Supported Cytosol "Intracellular and membrane" NA NA 560000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA017896: AB_1849478, HPA019097: AB_1849480" "prognostic unfavorable (1.02e-4)" "unprognostic (2.46e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (2.04e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (8.95e-5)" "unprognostic (7.31e-3)" "unprognostic (4.76e-1)" "unprognostic (4.00e-3)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "prognostic unfavorable (1.70e-5)" "unprognostic (3.92e-1)" "unprognostic (3.40e-2)" "unprognostic (6.32e-2)" "prognostic unfavorable (3.04e-5)" 34.2 31.0 33.3 43.3 36.5 32.0 31.7 34.2 46.2 32.6 49.9 39.8 27.6 29.1 37.3 53.8 23.3 29.9 32.9 38.6 45.7 42.7 46.0 34.0 47.2 38.1 34.7 26.7 78.5 58.1 36.5 39.9 42.0 26.8 48.6 46.9 36.1 29.3 48.1 43.4 26.0 49.8 33.2 22.3 47.4 51.5 43.4 40.7 51.5 45.0 67.3 54.0 29.4 35.2 231.4 119.8 103.4 364.5 191.9 286.8 172.0 332.4 330.5 184.0 369.8 159.5 115.4 375.9 96.2 443.1 281.6 174.5 262.6 230.2 327.7 92.9 82.5 182.6 84.8 141.1 604.0 267.6 149.8 272.5 391.9 265.8 304.9 128.1 241.6 354.1 350.2 465.4 296.7 154.7 216.8 204.3 259.6 222.4 183.4 114.0 90.1 299.0 219.5 109.1 117.9 177.4 88.1 261.5 509.2 182.8 225.3 409.3 208.2 82.2 262.9 164.9 217.9 403.8 390.8 445.9 289.4 398.8 392.9 40.0 27.0 24.1 22.9 35.8 27.4 21.0 26.0 28.8 35.8 16.3 25.2 30.2 5.2 20.9 41.7 18.5 31.9 23.9 33.3 36.5 34.2 46.2 38.6 45.7 38.1 34.7 42.0 33.2 43.4 35.2 10.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.1 0.0 0.0 0.0 0.0 47.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 70.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 39.8 2.0 0.0 0.0 0.0 GAS1 ENSG00000180447 "Growth arrest specific 1" P54826 9 86944362-86947506 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 105.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 127.1;Muller glia cells: 90.3;Skeletal myocytes: 213.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 30.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 44.2;ASC diff: 29.3;BJ hTERT+: 59.8;HSkMC: 41.1;RH-30: 91.1" "Low region specificity" "Detected in all" "CAB024164, HPA036085, HPA066902" Approved Approved "Nuclear speckles" NA NA 27000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "CAB024164: AB_2107950, HPA036085: AB_2674932, HPA066902: AB_2685746" "unprognostic (2.78e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.97e-2)" "unprognostic (6.15e-2)" "unprognostic (2.84e-2)" "unprognostic (6.46e-2)" "unprognostic (6.91e-2)" "unprognostic (3.32e-1)" "unprognostic (1.28e-3)" "unprognostic (2.25e-3)" "unprognostic (4.30e-2)" "prognostic unfavorable (1.96e-5)" "prognostic unfavorable (8.26e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.13e-5)" "unprognostic (3.59e-2)" 81.5 6.4 3.6 16.6 4.4 0.2 38.3 3.5 4.4 27.1 16.1 27.6 2.2 105.4 15.2 5.8 60.7 10.5 27.1 3.2 2.7 12.5 2.2 7.8 6.8 3.8 3.8 45.1 11.2 1.9 8.4 22.1 3.6 22.6 2.3 3.3 13.1 9.6 12.2 22.2 9.3 43.4 3.4 3.6 16.3 1.8 3.8 7.1 15.9 9.3 3.1 22.5 27.1 6.8 0.0 0.0 7.5 44.2 29.3 10.9 0.8 8.8 59.8 2.9 2.6 0.0 0.1 0.0 0.5 15.8 0.3 0.6 0.0 0.3 1.2 5.2 17.8 0.0 25.0 0.0 14.9 0.1 0.7 41.1 6.3 1.0 5.3 0.0 0.0 0.9 0.0 0.0 12.6 0.0 0.0 0.4 9.5 0.3 0.1 9.6 91.1 0.0 0.4 0.0 1.0 4.0 12.9 0.0 14.1 4.8 0.1 0.2 0.1 13.0 3.6 0.9 3.0 0.0 0.0 0.0 0.4 0.6 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.4 3.5 4.4 3.2 2.7 3.8 3.8 3.6 3.4 3.8 6.8 15.8 0.0 0.6 2.0 0.4 25.9 7.5 10.9 10.2 8.3 3.9 28.3 5.5 0.0 3.1 14.7 10.4 21.5 7.8 0.1 9.8 0.5 0.1 2.4 36.6 5.6 0.0 0.4 1.2 0.4 3.7 127.1 1.1 2.0 0.0 2.1 22.9 0.3 5.8 5.0 2.6 0.3 0.0 1.0 15.4 0.9 32.3 2.2 17.8 1.9 0.2 90.3 7.2 8.5 4.4 0.2 0.0 12.4 2.1 4.5 0.0 2.6 0.7 3.2 39.5 213.7 15.4 0.3 1.3 1.0 12.5 4.5 2.1 0.8 0.2 0.4 GAS6 "AXLLG, AXSF, DKFZp666G247, FLJ34709" ENSG00000183087 "Growth arrest specific 6" Q14393 13 113820549-113864076 "Predicted secreted proteins" "Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 348.3;Sertoli cells: 322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 70.7" "Lineage enriched" "Detected in many" 50 "dendritic cells: 70.7" "Cell line enhanced" "Detected in many" "BJ: 347.0;BJ hTERT+: 494.0;HSkMC: 281.3;RPMI-8226: 493.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008275, HPA056080" Approved Approved "Centriolar satellite,Cytosol" "Secreted to blood" NA NA 8900000 3600000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Centriolar satellite" "HPA008275: AB_1849497, HPA056080: AB_2683032" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.97e-3)" "unprognostic (1.37e-1)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (2.09e-2)" "unprognostic (2.92e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.55e-1)" "unprognostic (4.81e-3)" "unprognostic (1.97e-1)" "unprognostic (2.16e-2)" "unprognostic (9.00e-2)" "prognostic unfavorable (8.93e-6)" 124.2 32.5 26.7 18.8 28.7 3.6 77.4 33.9 32.0 244.4 59.3 67.8 48.7 171.7 13.8 63.2 161.3 58.9 169.1 24.1 34.6 72.7 37.1 97.3 22.5 37.4 36.1 118.0 49.9 58.5 58.4 51.6 38.5 100.9 25.2 6.3 84.4 63.8 99.2 101.4 47.8 57.9 30.8 29.4 70.0 60.1 34.1 39.6 101.2 67.5 10.6 127.0 172.0 25.2 151.3 6.6 4.4 3.8 169.5 94.0 18.4 347.0 494.0 141.3 168.4 9.6 71.0 1.4 11.4 157.2 24.9 139.1 2.4 77.7 35.6 0.2 20.1 1.1 11.1 1.0 120.8 1.0 2.1 281.3 44.9 39.1 39.0 243.2 5.3 2.3 2.6 79.9 231.9 7.4 0.8 1.5 9.5 24.0 9.9 4.5 0.1 493.5 51.9 1.9 23.5 21.3 38.3 1.3 0.4 23.8 45.9 119.4 81.7 36.9 45.0 4.4 100.5 0.1 8.0 1.5 41.9 3.6 5.8 0.0 1.4 0.0 0.0 1.1 0.0 0.1 0.2 0.0 11.3 0.1 0.0 0.0 0.0 0.1 0.3 70.7 0.0 1.4 26.7 28.7 33.9 32.0 24.1 34.6 37.4 36.1 38.5 30.8 34.1 25.2 133.2 198.7 25.9 23.2 20.8 84.4 94.7 18.5 70.0 38.0 17.9 114.3 86.8 50.1 23.4 31.3 0.0 1.8 59.1 92.4 27.4 45.7 5.1 35.2 33.1 71.9 10.3 5.3 26.2 6.7 1.9 152.7 19.9 32.3 8.2 154.7 159.9 21.6 101.6 348.3 31.9 69.5 8.2 22.3 100.4 8.9 92.2 48.6 122.7 41.2 9.8 32.7 0.0 3.0 7.5 24.1 58.6 59.5 147.4 30.5 84.1 0.6 15.5 12.5 322.1 22.9 121.1 5.3 17.6 27.6 71.9 2.9 4.7 214.8 151.4 31.1 GASK1A "C3orf41, DKFZP434B172, FAM198A" ENSG00000144649 "Golgi associated kinase 1A" Q9UFP1 3 42979267-43060211 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.4;Extravillous trophoblasts: 2.6;Fibroblasts: 1.8;Hofbauer cells: 3.9;Syncytiotrophoblasts: 2.7" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.1;RPMI-8226: 3.4;SK-BR-3: 2.6;T-47d: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047726 Approved Supported Vesicles "Secreted - unknown location" NA NA 600000 "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA047726: AB_10960554" "unprognostic (2.16e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.93e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (2.69e-1)" "unprognostic (6.21e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.57e-4)" "unprognostic (4.45e-2)" "unprognostic (2.09e-2)" "unprognostic (3.49e-2)" "unprognostic (3.81e-1)" 5.5 2.1 4.9 2.5 6.4 0.0 4.2 6.3 3.8 10.6 4.9 3.4 0.7 9.8 2.2 1.8 11.3 5.3 1.7 4.1 5.9 1.0 13.1 3.1 0.7 8.8 7.7 6.8 2.0 0.1 3.0 2.0 7.6 2.6 1.0 3.9 2.6 2.2 1.4 1.7 2.1 6.0 6.3 0.9 3.4 2.9 10.0 0.6 2.1 0.8 0.3 3.2 3.9 5.2 0.0 0.0 0.0 3.1 0.1 0.0 1.1 0.2 0.3 0.0 0.0 0.1 0.9 0.0 1.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 1.9 0.7 0.0 0.0 0.6 0.4 1.2 0.8 0.0 0.4 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.0 1.9 0.0 0.0 0.0 0.0 3.4 0.0 0.5 0.1 0.3 0.0 2.6 0.0 0.1 6.7 0.9 0.0 0.4 0.6 1.4 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.9 6.4 6.3 3.8 4.1 5.9 8.8 7.7 7.6 6.3 10.0 5.2 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 GAST GAS ENSG00000184502 Gastrin P01350 17 41712331-41715969 "Cancer-related genes, FDA approved drug targets, Predicted secreted proteins" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "stomach 1: 9556.1" "Cell type enriched" "Detected in some" 5 "Glandular and luminal cells: 103.7" "Group enriched" "Detected in many" 6 "pancreatic cancer: 38.8;stomach cancer: 23.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 34.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" CAB000038 Enhanced "Secreted to digestive system" NA NA 87000 "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "CAB000038: " "unprognostic (1.27e-1)" "unprognostic (4.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.07e-2)" "unprognostic (2.75e-2)" "unprognostic (5.68e-2)" "unprognostic (2.11e-1)" "unprognostic (2.85e-1)" "unprognostic (3.17e-1)" "unprognostic (9.07e-2)" 0.0 0.0 0.9 0.0 0.6 0.0 0.7 0.4 0.9 0.2 0.4 0.0 57.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.3 0.0 3.7 0.0 0.8 1.0 0.0 0.0 0.0 0.1 4.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 9.3 9556.1 0.3 2.5 4.3 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 5.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 34.8 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.4 0.9 0.5 2.5 0.8 1.0 1.0 0.6 2.5 0.6 0.8 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.3 0.9 0.4 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 0.1 2.2 13.5 18.7 0.7 0.0 0.0 0.0 0.0 0.1 1.0 0.5 103.7 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.8 0.2 0.2 0.0 0.0 8.8 1.0 0.0 0.0 0.4 GATD1 "FLJ34283, PDDC1" ENSG00000177225 "Glutamine amidotransferase like class 1 domain containing 1" Q8NB37 11 767220-777488 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 44.8;Alveolar cells type 2: 22.1;Collecting duct cells: 22.0;Theca cells: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 120.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008812 Uncertain Supported Nucleoplasm "Secreted to blood" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA008812: AB_10962724" "unprognostic (3.39e-1)" "unprognostic (2.48e-2)" "unprognostic (1.31e-1)" "unprognostic (3.58e-2)" "unprognostic (2.82e-2)" "unprognostic (3.03e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (3.50e-2)" "unprognostic (2.19e-1)" "unprognostic (5.67e-2)" "unprognostic (5.23e-3)" "unprognostic (4.89e-3)" "prognostic favorable (3.79e-5)" "unprognostic (2.84e-2)" "unprognostic (8.40e-2)" "unprognostic (6.11e-2)" "unprognostic (6.61e-3)" 15.9 37.5 37.7 11.3 35.8 7.9 16.7 35.1 37.8 22.7 36.6 23.3 15.4 24.9 12.6 23.7 22.7 7.3 16.3 37.4 36.5 24.0 19.3 15.4 11.2 46.4 41.8 25.9 15.9 10.5 30.1 9.2 35.8 23.0 6.5 9.7 17.5 12.2 14.4 21.0 18.2 7.9 38.4 19.6 17.8 18.6 45.3 8.8 22.0 6.5 6.8 19.7 20.4 37.5 41.3 22.3 22.2 23.9 10.2 15.6 20.9 24.2 10.5 22.0 19.3 15.8 62.5 22.1 8.6 16.0 23.2 42.7 16.7 21.6 11.0 28.1 120.5 13.0 38.8 36.0 17.5 25.4 27.8 22.4 23.2 9.3 14.2 19.9 17.1 25.8 34.2 20.0 12.4 11.0 29.3 27.5 21.3 13.4 42.8 31.4 15.1 28.0 19.2 9.1 56.9 22.3 22.9 32.0 16.6 5.7 28.5 16.8 31.3 23.2 17.5 12.7 18.8 23.4 12.9 28.4 35.4 33.9 19.6 1.0 5.2 0.9 2.9 6.6 2.1 2.7 3.0 2.9 6.9 2.3 2.4 1.7 0.5 1.2 2.6 4.0 1.4 2.0 37.7 35.8 35.1 37.8 37.4 36.5 46.4 41.8 35.8 38.4 45.3 37.5 8.7 44.8 22.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 11.9 10.4 0.0 0.0 7.4 22.0 0.0 13.8 5.2 0.0 5.9 10.3 0.0 11.8 15.2 3.8 0.0 0.0 0.0 7.6 7.9 8.5 0.0 9.6 6.3 19.2 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 4.6 0.0 0.0 0.0 0.0 16.6 0.0 0.0 1.3 0.0 0.0 14.7 7.3 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 9.6 3.9 25.8 0.0 0.0 GATD3A "C21orf33, D21S2048E, ES1, GT335, HES1, KNP-I, KNP-Ia, KNPH, KNPI" ENSG00000160221 "Glutamine amidotransferase like class 1 domain containing 3A" P0DPI2 21 44133610-44210114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 178.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 7.0;Granulosa cells: 4.6;Hofbauer cells: 8.6;Proximal tubular cells: 4.8;Theca cells: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 156.3;U-266/70: 128.2;U-266/84: 117.9" HPA018517 Supported Approved Centrosome,Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria Centrosome "HPA018517: AB_2669899" "unprognostic (9.61e-3)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (3.80e-2)" "unprognostic (1.54e-3)" "unprognostic (6.57e-2)" "unprognostic (8.19e-2)" "unprognostic (1.36e-2)" "unprognostic (8.61e-3)" "unprognostic (9.43e-2)" "unprognostic (4.60e-3)" "unprognostic (1.97e-3)" "unprognostic (1.40e-1)" "unprognostic (6.96e-2)" "unprognostic (1.30e-2)" 21.3 25.3 10.4 7.7 11.8 1.3 18.6 12.2 50.3 18.9 8.2 19.0 2.0 12.1 25.7 19.8 27.4 1.3 68.4 10.3 11.9 51.0 78.2 12.3 8.0 15.0 13.5 18.8 18.2 18.3 16.0 5.8 12.8 16.6 1.0 6.1 18.2 7.8 60.2 17.1 15.7 1.0 12.3 16.3 19.2 11.3 13.4 8.2 15.2 178.6 20.7 18.3 15.1 12.7 1.8 3.7 2.6 0.7 34.4 34.0 52.0 64.2 39.7 49.2 38.9 82.4 0.6 156.3 0.9 0.2 1.6 0.8 0.4 35.3 25.1 35.0 77.7 8.0 11.3 49.0 38.3 3.1 1.1 0.4 2.8 15.7 1.9 29.5 2.2 40.0 31.7 56.5 19.7 6.5 1.6 3.9 1.4 4.9 9.0 1.6 0.8 28.4 2.6 1.2 55.8 0.6 1.3 1.6 52.7 1.0 2.8 4.4 33.8 22.7 1.4 38.1 0.8 128.2 117.9 2.5 1.7 10.2 29.5 10.8 16.4 9.6 16.9 24.9 15.6 27.4 21.5 21.3 3.7 28.1 17.6 15.1 7.6 21.0 40.4 17.6 18.5 23.1 10.4 11.8 12.2 50.3 10.3 11.9 15.0 13.5 12.8 12.3 13.4 12.7 4.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 7.0 2.5 0.0 0.0 0.0 0.0 0.0 2.6 3.4 0.0 3.9 1.6 0.0 2.6 1.1 2.1 0.0 0.0 0.0 2.5 3.6 1.9 0.0 1.9 0.0 4.6 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.0 4.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 2.6 0.8 11.9 0.0 0.0 GATD3B ENSG00000280071 "Glutamine amidotransferase like class 1 domain containing 3B" A0A0B4J2D5 21 5079294-5128413 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal tubular cells: 17.6;Ductal cells: 6.9;Hofbauer cells: 8.0;monocytes: 7.8;Proximal tubular cells: 31.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA018517 Uncertain Approved Centrosome,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Centrosome "HPA018517: AB_2669899" "unprognostic (4.87e-2)" "unprognostic (2.69e-3)" "unprognostic (1.99e-1)" "unprognostic (1.11e-1)" "unprognostic (2.96e-1)" "unprognostic (6.47e-2)" "unprognostic (1.43e-2)" "unprognostic (2.39e-2)" "unprognostic (7.65e-2)" "unprognostic (1.71e-2)" "unprognostic (1.15e-2)" "unprognostic (3.33e-2)" "unprognostic (6.67e-4)" "unprognostic (1.88e-2)" "unprognostic (6.80e-2)" "unprognostic (4.25e-1)" "unprognostic (2.84e-2)" 53.8 77.8 82.0 34.9 87.3 31.7 48.6 88.9 90.2 40.9 76.0 55.1 71.8 36.9 27.5 59.4 44.4 41.2 195.5 78.2 87.4 141.7 239.9 34.5 53.8 89.0 86.3 66.6 52.7 61.9 54.8 40.2 90.2 43.9 57.5 32.2 60.1 33.4 208.0 40.6 51.3 32.4 83.9 48.2 50.1 33.0 89.9 35.9 55.1 225.6 28.1 40.0 41.1 85.5 55.8 52.7 57.1 98.7 42.8 38.3 23.7 0.0 4.5 1.9 2.9 7.0 54.8 2.6 61.9 62.9 51.7 38.8 77.2 34.7 1.1 36.8 32.8 217.2 60.1 47.6 41.7 94.8 39.7 80.4 69.6 28.3 57.1 39.5 64.4 66.1 86.6 51.2 34.9 118.5 94.4 103.6 110.9 150.0 80.5 190.1 43.1 223.3 72.4 49.8 48.5 96.4 76.7 138.9 52.0 28.4 146.2 131.4 19.7 27.7 39.0 2.5 33.7 80.7 79.2 37.6 64.9 192.0 20.7 87.3 110.4 60.4 102.2 123.5 101.4 153.3 129.7 107.0 147.7 167.1 124.6 95.2 21.7 136.1 167.7 96.3 145.3 190.3 82.0 87.3 88.9 90.2 78.2 87.4 89.0 86.3 90.2 83.9 89.9 85.5 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 1.1 0.0 0.0 0.0 0.0 0.0 2.9 1.4 0.0 17.6 6.9 0.0 1.1 1.9 0.7 0.0 0.0 0.0 5.0 3.2 0.3 0.0 2.0 0.0 0.5 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 7.8 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.7 0.0 0.0 31.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.4 0.7 1.9 0.0 0.0 GBA "GBA1, GLUC" ENSG00000177628 "Glucosylceramidase beta" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 65.2;Syncytiotrophoblasts: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" NA NA 470000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "CAB037171: AB_1078958, CAB037289: AB_1078957, HPA006667: AB_1078979" "unprognostic (6.03e-2)" "unprognostic (6.02e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-1)" "unprognostic (6.00e-3)" "unprognostic (2.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.76e-2)" "unprognostic (1.22e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-1)" "unprognostic (2.94e-2)" 23.9 37.9 22.5 24.8 24.4 41.7 25.1 25.9 24.3 26.7 27.4 35.1 23.9 22.9 50.2 27.6 20.5 28.3 19.1 26.1 27.7 33.6 33.7 28.3 19.9 27.3 28.0 16.9 33.4 103.1 43.8 39.2 36.2 23.3 39.8 12.4 26.8 33.6 9.1 33.4 22.5 29.7 25.0 29.0 22.7 8.8 29.2 19.7 37.7 13.6 28.0 27.1 21.9 29.5 38.0 72.2 25.1 34.2 254.8 55.8 29.3 65.4 230.4 95.3 119.0 43.2 135.7 26.3 70.4 153.7 152.0 76.2 35.9 46.4 50.3 55.5 25.1 21.8 45.1 23.2 73.6 25.8 87.0 73.4 38.2 199.7 30.2 100.2 85.6 22.2 23.4 42.9 113.5 82.6 32.5 11.9 16.3 61.9 51.2 26.8 41.9 108.1 63.9 29.0 23.9 33.5 57.4 136.4 145.3 45.6 102.6 63.3 65.7 71.7 31.7 91.9 53.7 86.2 78.6 20.4 126.6 23.4 56.4 21.4 36.0 15.3 20.8 35.8 13.2 11.1 15.7 13.8 22.4 7.8 11.0 11.7 28.9 11.6 37.2 12.5 23.4 23.3 22.5 24.4 25.9 24.3 26.1 27.7 27.3 28.0 36.2 25.0 29.2 29.5 6.8 3.2 5.1 3.3 8.8 6.0 5.8 9.5 4.6 4.0 12.7 6.5 8.8 17.2 8.1 12.9 2.1 30.7 6.2 36.1 3.9 30.5 1.4 12.3 9.7 12.2 14.6 7.4 3.4 32.4 27.9 18.6 20.9 17.9 7.0 7.9 17.2 23.2 65.2 5.0 2.7 11.6 4.1 33.3 9.9 2.8 9.9 26.8 26.6 1.0 22.8 11.7 12.3 0.5 3.3 29.5 15.8 9.1 19.8 6.7 28.6 20.6 8.5 6.0 0.0 9.4 21.6 22.5 12.5 8.6 4.4 59.4 8.5 6.0 10.4 6.5 GBA2 "AD035, DKFZp762K054, KIAA1605, SPG46" ENSG00000070610 "Glucosylceramidase beta 2" Q9HCG7 9 35736866-35749228 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 114.7;Rod photoreceptor cells: 102.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024026 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Golgi apparatus" Cytosol "HPA024026: AB_1849530" "unprognostic (3.34e-2)" "unprognostic (2.90e-1)" "unprognostic (2.99e-1)" "unprognostic (1.06e-2)" "unprognostic (1.41e-1)" "unprognostic (5.83e-3)" "unprognostic (2.20e-2)" "unprognostic (2.09e-2)" "unprognostic (3.99e-2)" "unprognostic (8.69e-2)" "prognostic favorable (6.00e-4)" "unprognostic (9.01e-3)" "prognostic favorable (1.24e-11)" "unprognostic (7.62e-3)" "unprognostic (2.94e-1)" "unprognostic (7.69e-2)" "prognostic favorable (6.60e-4)" 39.3 45.7 48.5 23.2 47.5 16.3 39.9 52.8 53.7 46.4 63.3 83.5 54.2 44.6 26.9 36.3 44.2 26.3 83.3 47.2 54.2 84.4 65.9 54.1 24.6 54.1 56.2 39.8 54.1 37.2 65.5 24.7 56.1 60.2 41.0 71.1 50.0 27.7 75.8 39.3 89.7 22.9 45.1 58.5 63.9 30.8 58.9 18.3 61.7 43.7 21.6 53.0 40.9 48.7 18.1 29.3 39.6 38.4 18.8 11.4 40.0 24.1 18.8 23.9 25.0 32.8 14.1 19.3 17.1 14.7 51.5 18.4 38.2 16.2 12.0 27.5 26.2 20.8 87.8 35.6 20.8 31.2 49.4 19.8 29.8 20.3 21.1 57.9 63.4 18.9 20.7 36.0 22.6 18.0 8.5 32.0 41.2 36.6 45.7 15.5 16.0 16.3 33.3 41.9 32.2 43.0 13.5 33.3 24.5 48.1 22.8 27.8 44.6 25.8 30.9 22.4 29.9 24.2 16.5 16.0 32.3 11.3 20.5 11.1 2.9 2.0 3.8 3.9 2.5 3.7 3.7 4.7 2.8 4.7 2.2 1.9 3.2 2.4 2.5 4.4 2.8 2.2 48.5 47.5 52.8 53.7 47.2 54.2 54.1 56.2 56.1 45.1 58.9 48.7 12.7 12.8 8.0 45.1 11.2 7.4 18.2 9.4 6.2 77.5 15.0 10.8 13.7 17.2 14.5 27.6 114.7 11.1 16.6 71.7 21.5 10.5 14.1 10.0 8.1 16.0 35.8 17.2 23.5 12.0 10.2 8.0 46.4 13.8 14.0 18.7 30.7 20.1 9.2 52.2 26.4 35.8 16.2 12.8 10.7 24.3 12.5 10.7 12.4 8.4 13.3 16.2 12.3 18.1 20.2 15.1 57.6 9.8 11.7 15.8 87.4 17.8 17.9 102.9 13.1 12.2 12.2 9.2 5.7 8.8 9.9 22.2 9.4 11.3 41.4 26.3 GBF1 "ARF1GEF, KIAA0248" ENSG00000107862 "Golgi brefeldin A resistant guanine nucleotide exchange factor 1" Q92538 10 102245371-102382899 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 28.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037759, HPA037760" Uncertain Supported "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA037759: AB_10671884, HPA037760: AB_2675651" "unprognostic (5.97e-2)" "unprognostic (3.33e-1)" "unprognostic (2.74e-3)" "unprognostic (7.02e-2)" "unprognostic (2.03e-1)" "unprognostic (6.72e-2)" "unprognostic (3.78e-2)" "unprognostic (8.28e-2)" "unprognostic (1.12e-2)" "unprognostic (5.34e-3)" "unprognostic (2.04e-2)" "unprognostic (6.06e-2)" "unprognostic (1.87e-1)" "unprognostic (2.10e-1)" "unprognostic (2.24e-1)" "unprognostic (3.02e-1)" "unprognostic (3.09e-2)" 19.4 21.1 31.5 16.0 31.7 25.0 19.3 28.7 47.2 21.7 34.9 24.6 20.6 23.5 12.7 21.9 19.7 9.8 30.0 32.2 27.7 21.7 23.2 20.5 14.6 28.5 37.3 21.6 25.6 24.4 31.5 11.5 30.6 24.2 13.9 19.2 24.5 15.2 48.1 24.9 25.8 16.4 27.1 21.7 21.2 20.5 29.8 11.8 25.4 30.1 13.8 21.7 20.5 29.1 19.4 49.7 23.3 25.1 62.9 40.7 28.1 37.7 56.0 45.3 48.1 52.7 35.1 21.7 29.7 59.6 33.8 38.6 45.9 52.8 33.8 35.4 36.9 33.3 38.1 44.6 26.4 35.2 46.8 37.3 28.0 60.7 57.5 77.2 45.2 22.5 20.7 53.7 41.8 36.9 24.2 38.9 15.4 29.5 35.6 33.6 72.1 18.8 39.3 30.9 15.0 16.3 30.2 22.3 26.5 33.1 50.4 30.8 60.5 29.1 29.6 37.7 55.6 32.4 36.3 26.5 30.0 36.3 22.1 28.6 4.5 4.3 4.9 5.0 5.9 6.5 3.6 6.5 5.0 3.9 5.7 5.3 4.6 4.6 4.1 4.2 7.4 3.9 31.5 31.7 28.7 47.2 32.2 27.7 28.5 37.3 30.6 27.1 29.8 29.1 12.5 12.8 10.1 56.5 15.5 9.8 5.5 10.6 17.6 24.7 15.7 12.8 17.0 15.7 10.9 12.9 56.3 12.2 15.1 31.4 3.9 12.5 4.9 14.3 18.1 12.3 12.0 13.9 72.1 16.7 16.3 14.6 31.1 15.6 7.6 10.3 8.2 17.6 12.2 52.2 73.0 21.9 12.2 11.0 5.0 4.7 10.2 13.4 12.4 66.5 9.5 11.1 9.2 80.9 71.1 18.6 20.7 11.3 46.0 7.7 27.1 9.0 12.3 41.0 6.6 21.7 12.3 36.0 25.4 20.7 13.1 17.6 16.0 19.1 19.4 6.7 GBGT1 "A3GALNT, FS, MGC44848, UDP-GalNAc" ENSG00000148288 "Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)" Q8N5D6 9 133152948-133163933 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Hofbauer cells: 21.3;Kupffer cells: 31.9;Macrophages: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 64.1;HMC-1: 57.1;HUVEC TERT2: 24.0;NB-4: 29.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051298 Approved "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA051298: AB_2681428" "unprognostic (4.63e-3)" "unprognostic (8.03e-2)" "prognostic unfavorable (6.22e-4)" "unprognostic (2.70e-1)" "unprognostic (8.87e-2)" "unprognostic (4.38e-1)" "unprognostic (2.97e-2)" "unprognostic (7.43e-2)" "unprognostic (9.04e-2)" "unprognostic (2.27e-3)" "unprognostic (2.35e-1)" "unprognostic (9.50e-2)" "prognostic unfavorable (3.46e-5)" "unprognostic (2.92e-2)" "unprognostic (1.01e-1)" "unprognostic (3.41e-2)" "unprognostic (6.35e-2)" 9.9 10.5 6.3 11.0 5.9 9.9 6.5 11.8 7.0 5.4 11.8 5.3 3.3 6.7 2.7 3.6 7.4 7.5 6.7 5.9 8.2 5.6 1.3 9.7 9.7 13.5 11.2 12.5 3.4 4.8 4.2 12.8 13.8 6.1 3.2 1.0 4.8 4.2 2.2 3.5 6.7 6.7 7.7 8.9 22.2 1.3 11.5 2.7 6.7 2.9 8.1 6.0 6.3 8.5 0.1 1.6 1.5 0.0 1.0 1.1 0.5 4.7 3.8 2.6 0.1 0.0 0.9 1.2 15.5 4.7 1.7 17.3 10.5 1.0 0.1 0.0 0.5 64.1 1.1 0.0 12.4 2.4 57.1 5.3 1.7 0.6 0.1 10.5 24.0 0.8 18.7 0.2 1.0 0.3 0.2 29.0 4.9 0.5 0.4 4.5 0.4 1.7 1.6 0.2 0.4 1.8 0.0 2.6 0.1 2.0 0.1 14.0 14.8 0.0 2.0 1.9 0.1 0.0 0.0 0.1 0.3 10.2 0.8 6.2 10.7 5.2 0.2 7.2 0.4 1.8 0.3 0.0 3.0 2.7 0.1 0.1 1.7 0.2 6.4 2.2 0.2 2.5 6.3 5.9 11.8 7.0 5.9 8.2 13.5 11.2 13.8 7.7 11.5 8.5 1.6 0.0 1.7 4.9 4.9 0.8 2.2 0.6 2.8 0.3 4.1 2.7 2.6 1.5 0.7 1.8 0.0 2.4 0.0 0.6 0.0 3.2 0.0 0.5 1.8 1.8 0.0 16.4 2.4 0.6 1.1 7.3 2.6 0.3 11.4 3.6 0.7 0.0 21.3 0.0 1.9 0.3 0.0 31.9 3.1 0.0 7.5 22.0 0.0 5.6 11.1 2.4 0.0 1.5 0.0 0.8 12.1 1.9 0.7 1.5 0.1 1.6 0.0 0.2 0.0 3.9 6.2 0.1 0.1 1.4 1.1 3.6 2.0 0.5 1.2 1.7 GC "DBP, hDBP, VDBP" ENSG00000145321 "GC vitamin D binding protein" P02774 4 71741696-71804041 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" Transport Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 8260.1" "Group enriched" "Detected in some" 27 "Cholangiocytes: 1552.8;Hepatocytes: 3017.1" "Cancer enriched" "Detected in many" 18 "liver cancer: 1016.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 2.0;RH-30: 3.0;SiHa: 1.8;U-698: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001526, CAB008596, HPA019855" Supported "Secreted to blood" NA NA 143000000000 73000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 15: Hepatocytes - Hemostasis" "CAB008596: AB_1622398, HPA001526: AB_1078959, HPA019855: AB_1849545" "prognostic favorable (8.08e-4)" "unprognostic (1.06e-3)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.55e-1)" "unprognostic (2.15e-1)" 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 60.3 0.0 0.6 0.1 0.0 495.5 0.1 0.0 0.0 46.1 8260.1 0.0 0.2 0.1 0.1 0.0 44.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.0 0.0 0.0 1.8 51.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.4 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.3 0.0 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 7.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 1552.8 0.0 0.0 0.0 0.0 0.0 0.0 5.9 39.5 0.5 0.1 0.0 2.0 0.0 37.5 0.1 16.2 0.2 0.0 0.0 0.0 0.0 0.0 58.5 3017.1 0.1 0.0 0.1 0.7 0.0 83.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 0.0 0.0 GCG "GLP-1, GLP1, GLP2, GRPP" ENSG00000115263 Glucagon P01275 2 162142882-162152404 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "pancreas: 1943.6" "Cell type enriched" "Detected in some" 23 "Enteroendocrine cells: 5457.0" "Cancer enriched" "Detected in some" 209 "pancreatic cancer: 428.4" "Region enriched" "Detected in single" 55 "medulla oblongata: 6.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 133.4;U-2 OS: 186.8;U-698: 44.5" "Region enriched" "Detected in single" 10 "pons and medulla: 3.5" "Region enriched" "Detected in some" 5 "spinal cord: 13.7" "CAB000040, HPA036760, HPA036761" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" NA NA 127000 420000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Endoplasmic reticulum" Vesicles "CAB000040: AB_10013726, HPA036760: AB_2675296, HPA036761: AB_2675297" "unprognostic (3.13e-3)" "unprognostic (9.99e-2)" "unprognostic (1.16e-2)" "unprognostic (1.26e-2)" 20.3 0.1 0.0 3.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 84.4 3.4 0.6 0.0 5.3 0.0 4.1 2.5 0.0 0.0 41.9 0.0 0.2 3.5 6.2 0.0 0.1 1943.6 0.0 0.0 0.1 0.1 0.8 151.9 0.0 0.3 0.0 0.0 37.2 130.2 0.8 0.0 0.2 41.2 0.0 0.0 0.4 0.6 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.4 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 186.8 0.2 12.1 0.0 5.6 44.5 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.2 0.0 0.0 0.3 0.1 5457.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 91.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 230.9 8.5 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 22.9 0.0 GCGR GGR ENSG00000215644 "Glucagon receptor" P47871 17 81804132-81814008 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "kidney: 50.0;liver: 169.6" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 74.6" "Cancer enriched" "Detected in many" 4 "liver cancer: 10.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.0;MCF7: 1.4;SK-BR-3: 1.2;U-87 MG: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071228 Uncertain "Golgi apparatus" NA NA "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "HPA071228: AB_2686368" "unprognostic (3.28e-4)" "unprognostic (9.30e-2)" "unprognostic (2.20e-1)" "unprognostic (1.53e-4)" "unprognostic (1.11e-1)" "unprognostic (2.30e-3)" "unprognostic (4.38e-2)" "unprognostic (1.79e-3)" "unprognostic (2.18e-1)" "unprognostic (2.77e-1)" "unprognostic (3.09e-1)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (5.99e-3)" "unprognostic (1.71e-1)" "unprognostic (1.17e-3)" "unprognostic (8.36e-3)" 0.2 2.5 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.2 0.0 0.8 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.4 50.0 169.6 0.0 0.1 0.3 0.1 0.0 1.4 6.3 0.2 0.0 0.2 0.2 0.0 0.7 0.1 0.0 0.0 1.5 0.6 0.0 0.1 0.1 0.1 0.9 0.0 0.0 0.2 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.4 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.9 0.0 0.6 0.0 0.5 0.0 0.3 0.6 0.0 0.3 3.7 2.1 0.0 0.0 0.1 3.9 0.2 0.1 0.4 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.4 74.6 0.1 0.0 0.5 0.0 0.0 1.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.6 0.4 0.0 0.0 0.0 0.2 0.4 0.5 0.4 0.0 0.2 0.0 0.1 0.0 GCNT7 "C20orf105, dJ1153D9.2" ENSG00000124091 "Glucosaminyl (N-acetyl) transferase family member 7" Q6ZNI0 20 56491492-56525925 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "bone marrow: 4.4" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Excitatory neurons: 1.4;Inhibitory neurons: 1.2;Late spermatids: 1.0;Oligodendrocyte precursor cells: 3.0;Oligodendrocytes: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA052617, HPA059403" Uncertain Approved "Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear bodies, Vesicles" Cytosol "HPA052617: AB_2681886, HPA059403: " "unprognostic (3.57e-2)" "unprognostic (1.39e-1)" "unprognostic (7.74e-2)" "unprognostic (1.89e-1)" "unprognostic (3.96e-2)" "unprognostic (9.08e-2)" "unprognostic (3.10e-1)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (2.38e-1)" "unprognostic (9.69e-2)" "unprognostic (2.84e-2)" "unprognostic (2.16e-3)" "unprognostic (1.84e-1)" "unprognostic (1.74e-1)" "unprognostic (1.96e-1)" "unprognostic (8.69e-2)" 0.0 0.1 0.1 0.3 0.2 4.4 0.0 0.6 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.1 0.0 0.2 0.4 0.1 0.0 0.1 0.2 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.2 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.9 0.0 0.1 0.2 0.2 0.0 0.1 0.2 0.6 0.2 0.1 0.2 0.3 0.2 0.3 0.1 0.4 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GCSH ENSG00000140905 "Glycine cleavage system protein H" P23434 16 81081945-81096395 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 553.4;Extravillous trophoblasts: 1476.4;Proximal tubular cells: 655.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041368, HPA057079" Supported Approved Vesicles "Intracellular and membrane" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA041368: AB_10804001, HPA057079: " "unprognostic (4.09e-2)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (2.47e-3)" "unprognostic (2.55e-3)" "unprognostic (4.87e-2)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.96e-2)" "unprognostic (6.92e-2)" "unprognostic (2.80e-2)" "prognostic favorable (6.26e-6)" "unprognostic (1.12e-2)" "unprognostic (2.59e-1)" "unprognostic (6.31e-2)" "unprognostic (6.47e-2)" 28.7 20.1 58.9 6.9 66.5 6.3 24.2 62.9 113.8 18.2 50.8 16.0 7.2 17.5 68.9 15.5 19.8 11.7 38.1 55.8 60.9 78.2 118.9 10.8 6.7 60.1 66.0 18.4 19.7 31.0 14.3 26.0 61.1 18.7 13.0 15.6 15.6 16.7 59.3 10.1 9.5 11.8 61.7 6.3 17.5 7.4 63.7 10.4 96.4 63.6 9.3 18.3 15.2 67.8 63.6 28.3 82.4 37.0 40.4 30.9 175.5 35.9 26.4 43.3 20.6 37.0 57.2 17.2 32.3 15.9 31.9 33.3 64.5 36.5 71.6 4.7 86.7 21.8 34.9 114.6 45.7 70.3 24.1 32.0 47.8 26.8 53.7 13.0 22.3 45.1 86.3 3.4 42.9 67.7 45.9 138.8 113.0 49.6 57.5 72.7 44.1 25.5 98.4 56.4 43.7 45.3 53.3 32.9 70.8 63.9 48.3 33.2 19.8 27.6 49.3 44.0 37.8 14.7 31.8 102.1 18.2 41.3 22.6 3.6 1.3 1.3 2.8 2.1 4.6 3.5 2.6 4.0 3.9 2.5 4.4 5.9 1.7 7.0 1.7 10.8 2.2 2.4 58.9 66.5 62.9 113.8 55.8 60.9 60.1 66.0 61.1 61.7 63.7 67.8 31.1 3.2 5.9 16.3 24.8 29.1 94.6 73.6 52.3 43.7 97.9 115.6 12.9 44.3 31.4 80.9 37.5 553.4 13.8 15.3 295.4 70.0 32.4 34.8 128.3 31.9 26.4 71.1 12.6 42.5 1476.4 61.6 31.1 55.2 36.3 38.5 33.2 352.0 118.8 38.7 11.9 34.3 67.1 19.7 34.6 19.5 140.8 18.8 85.4 4.7 17.7 215.8 19.6 19.6 35.2 42.3 17.8 141.1 51.7 123.9 13.7 655.9 20.0 45.7 32.9 46.2 50.2 20.7 77.3 78.4 27.1 228.8 16.3 114.5 49.4 69.8 GDF1 ENSG00000130283 "Growth differentiation factor 1" P27539 19 18868545-18896158 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.7;pituitary gland: 1.5;skeletal muscle: 3.9;testis: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.8;SH-SY5Y: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 38: EFO-21 - Unknown function" 0.0 0.1 1.5 0.0 2.1 0.0 0.1 1.4 3.6 0.3 0.5 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.6 1.7 1.1 0.0 0.0 0.0 0.0 3.0 2.0 0.4 0.1 0.0 1.5 0.0 2.3 0.2 0.0 0.0 0.1 0.0 3.9 0.0 0.1 0.0 1.9 0.0 0.2 4.9 3.7 0.0 0.1 0.0 0.0 0.3 0.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.1 1.4 3.6 1.7 1.1 3.0 2.0 2.3 1.9 3.7 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.6;retina: 18.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 20.9;Cone photoreceptor cells: 16.7;Fibroblasts: 25.7;Rod photoreceptor cells: 34.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 13.5;MOLT-4: 3.0;SH-SY5Y: 5.5" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA015498: AB_1849584" "unprognostic (4.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.09e-1)" "unprognostic (3.17e-1)" "unprognostic (9.84e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-2)" "unprognostic (1.55e-1)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-7)" "unprognostic (3.49e-2)" "unprognostic (1.48e-1)" "unprognostic (2.59e-3)" "unprognostic (2.63e-1)" 12.4 3.2 5.4 0.3 5.4 0.0 9.7 5.1 4.0 2.6 0.6 2.5 0.0 4.2 0.2 2.4 1.6 2.2 4.4 5.9 3.3 0.1 0.1 19.6 0.8 2.6 5.8 0.3 13.3 0.0 0.7 0.0 1.4 2.2 0.3 18.4 8.8 0.2 2.2 3.1 0.6 0.4 2.5 0.1 1.8 7.1 5.5 0.4 9.7 10.4 1.0 1.3 1.7 3.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.4 5.1 4.0 5.9 3.3 2.6 5.8 1.4 2.5 5.5 3.7 2.4 0.0 0.6 0.0 0.0 0.4 0.1 0.0 0.0 20.9 0.1 0.0 0.8 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.6 0.2 25.7 0.0 0.0 1.3 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.0 0.0 2.6 0.7 0.9 0.2 1.8 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.6 1.6 0.4 1.3 0.0 0.9 0.0 0.4 0.0 0.0 0.0 GDF11 "BMP-11, BMP11" ENSG00000135414 "Growth differentiation factor 11" O95390 12 55743122-55757264 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 76.6;Cone photoreceptor cells: 77.2;Horizontal cells: 57.2;Rod photoreceptor cells: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HMC-1: 127.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060985, HPA069609" Approved Approved Vesicles "Secreted to blood" No No 46400 340000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA060985: AB_2684403, HPA069609: AB_2686159" "unprognostic (5.21e-2)" "unprognostic (1.62e-1)" "unprognostic (3.20e-2)" "unprognostic (2.41e-2)" "unprognostic (2.78e-2)" "unprognostic (3.39e-1)" "unprognostic (2.13e-1)" "unprognostic (2.62e-2)" "unprognostic (8.96e-3)" "unprognostic (1.23e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.69e-1)" "unprognostic (1.62e-2)" "unprognostic (1.27e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" "unprognostic (9.48e-2)" 3.6 4.0 22.5 3.7 17.5 1.8 2.3 16.4 17.8 6.8 15.9 5.4 1.6 7.6 2.0 2.4 5.0 4.6 7.5 18.1 18.5 3.0 1.3 3.6 2.8 22.0 26.6 5.7 2.9 2.9 4.7 2.0 20.9 6.0 1.6 21.6 4.8 9.4 1.8 1.5 3.7 4.6 18.3 5.6 2.7 1.1 22.3 4.6 3.6 2.0 1.8 5.9 3.4 17.7 4.9 7.6 32.8 18.6 24.4 17.8 8.2 10.1 9.5 12.5 10.7 26.0 2.1 9.5 13.0 10.5 5.9 4.6 25.0 18.0 4.3 18.2 22.7 11.7 12.3 4.1 4.9 9.8 127.7 17.2 1.0 18.3 5.2 14.0 16.4 12.7 13.2 30.1 16.0 9.2 16.0 8.5 26.4 0.3 18.9 25.1 8.9 5.9 7.7 6.6 22.2 13.6 6.2 2.8 2.6 13.3 10.7 10.7 10.1 15.0 22.9 11.9 7.4 8.1 2.6 4.9 8.0 9.7 10.8 0.2 0.2 0.5 1.2 0.1 1.0 0.7 0.7 0.7 0.2 0.7 0.6 0.8 0.3 0.2 0.4 0.7 0.5 0.1 22.5 17.5 16.4 17.8 18.1 18.5 22.0 26.6 20.9 18.3 22.3 17.7 8.4 0.0 1.1 19.2 10.9 0.5 9.8 0.6 4.0 76.6 6.3 6.6 25.6 1.5 0.9 0.0 77.2 3.6 16.6 1.5 0.0 5.0 0.6 9.9 35.2 8.0 10.7 11.1 4.3 1.4 5.3 13.3 3.1 18.0 5.7 7.6 6.4 0.2 1.6 57.2 10.8 1.9 0.0 1.9 0.7 0.8 9.0 4.4 3.6 1.9 4.1 30.6 22.6 17.1 3.2 3.3 4.1 5.7 4.1 9.8 3.4 0.5 0.1 53.1 13.1 31.1 18.1 2.9 4.1 3.0 0.9 4.7 18.9 7.2 2.2 6.2 GDF15 "MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB" ENSG00000130513 "Growth differentiation factor 15" Q99988 19 18374731-18389176 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 371.8;urinary bladder: 175.4" "Cell type enhanced" "Detected in many" "Club cells: 1160.8;Syncytiotrophoblasts: 4304.7;Urothelial cells: 3294.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Group enriched" "Detected in many" 5 "granulocytes: 2.7;monocytes: 1.2" "Cell line enhanced" "Detected in many" "BEWO: 416.5;Hep G2: 225.5;HHSteC: 564.9;TIME: 213.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011191, CAB062554, HPA070957" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 1260000 960000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "CAB062554: AB_2665632, HPA011191: AB_1078962, HPA070957: AB_2732168" "unprognostic (1.04e-1)" "unprognostic (1.89e-2)" "unprognostic (3.45e-2)" "unprognostic (3.36e-2)" "unprognostic (2.04e-2)" "unprognostic (2.39e-2)" "unprognostic (2.03e-2)" "unprognostic (2.30e-2)" "unprognostic (2.80e-1)" "unprognostic (2.89e-1)" "unprognostic (5.09e-2)" "unprognostic (1.46e-1)" "unprognostic (6.55e-3)" "unprognostic (3.81e-2)" "unprognostic (8.45e-2)" "unprognostic (1.25e-1)" "unprognostic (3.04e-3)" 34.8 11.7 1.3 1.5 1.4 0.4 24.9 1.0 2.3 18.9 40.9 29.2 4.5 13.6 2.2 4.8 5.5 19.9 4.5 4.3 1.3 371.8 88.6 46.9 0.6 2.0 1.7 4.7 112.3 25.9 12.3 86.9 1.5 105.3 24.4 1.2 12.5 4.6 5.5 6.4 12.3 1.9 1.2 11.4 75.5 1.6 2.5 0.3 11.2 0.5 1.7 175.4 19.2 1.6 1.8 95.6 9.4 3.5 22.3 18.5 416.5 33.1 17.9 1.2 18.8 4.2 29.6 0.4 58.8 3.0 97.0 0.7 0.0 12.2 4.7 0.2 2.2 0.9 9.2 225.5 564.9 0.1 35.7 48.8 140.1 90.7 58.6 0.7 99.5 0.0 152.4 0.7 22.9 23.5 0.1 0.8 5.4 34.4 52.5 0.2 3.7 0.2 69.9 94.6 0.9 1.0 0.4 5.5 127.9 35.1 2.6 0.4 213.1 0.0 7.4 1.8 1.5 1.5 4.0 0.4 51.9 0.1 27.8 0.0 0.7 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.7 0.0 1.2 0.0 0.0 0.1 1.3 1.4 1.0 2.3 4.3 1.3 2.0 1.7 1.5 1.2 2.5 1.6 6.6 35.3 62.4 0.0 1.8 1.3 350.6 366.1 0.0 0.1 54.2 15.5 0.7 47.1 1160.8 259.3 0.0 60.6 0.4 176.0 33.2 316.9 0.0 166.8 35.4 31.9 84.8 0.0 0.1 381.9 263.4 52.9 224.8 261.8 29.2 0.2 2.5 7.0 33.8 0.0 0.1 357.6 453.7 1.6 3.7 0.0 0.9 14.1 3.6 0.0 9.9 0.5 1.0 0.0 0.0 440.4 146.6 1.5 1.3 780.2 22.9 85.7 681.4 0.6 0.0 9.5 46.7 0.7 0.5 1.3 1.7 4304.7 5.5 3.4 291.0 3294.2 GDF2 "BMP-9, BMP9" ENSG00000263761 "Growth differentiation factor 2" Q9UK05 10 47322454-47327588 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Angiogenesis "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "liver: 18.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB023357 Uncertain "Secreted to blood" NA NA 2210000 740000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 43: Cardiomyocytes - Nuclear processes" "CAB023357: AB_2111086" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GDF3 ENSG00000184344 "Growth differentiation factor 3" Q9NR23 12 7689784-7695775 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "kidney: 2.9" "Cell type enriched" "Detected in some" 25 "Granulosa cells: 30.2" "Cancer enriched" "Detected in some" 422 "testis cancer: 383.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "NTERA-2: 452.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA018468 Uncertain "Secreted to blood" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "HPA018468: AB_1849586" "unprognostic (9.48e-2)" "unprognostic (3.90e-2)" "unprognostic (3.30e-2)" "unprognostic (1.86e-2)" "unprognostic (3.51e-1)" "unprognostic (5.40e-2)" "unprognostic (3.09e-1)" "unprognostic (2.08e-1)" "unprognostic (2.89e-1)" "unprognostic (1.07e-1)" "unprognostic (9.20e-2)" "unprognostic (1.25e-3)" "unprognostic (8.00e-3)" "unprognostic (1.00e-1)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 2.9 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.9 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 0.1 0.0 452.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 77.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GDF5 "BMP14, CDMP1" ENSG00000125965 "Growth differentiation factor 5" P43026 20 35433347-35454746 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Chondrogenesis "Cytokine, Growth factor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "salivary gland: 9.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.2;Basal prostatic cells: 1.0;granulocytes: 1.3" "Cancer enriched" "Detected in single" 7 "endometrial cancer: 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 17.6;BJ hTERT+: 5.4;GAMG: 9.4;HHSteC: 5.8;HSkMC: 14.4;U-87 MG: 6.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA015648 Uncertain "Secreted to blood" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "HPA015648: AB_1849589" "unprognostic (4.59e-3)" "unprognostic (3.48e-2)" "unprognostic (5.53e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (4.64e-1)" "unprognostic (2.17e-3)" "unprognostic (4.38e-2)" "unprognostic (1.40e-1)" "unprognostic (8.02e-2)" "unprognostic (2.77e-1)" "unprognostic (5.57e-3)" "unprognostic (2.13e-2)" "unprognostic (1.24e-1)" "unprognostic (1.38e-1)" "unprognostic (8.96e-3)" 0.9 0.1 0.1 0.0 0.4 0.0 0.6 0.1 0.3 0.3 0.3 1.6 0.0 0.4 0.1 0.0 0.1 0.2 0.4 0.1 0.2 0.3 0.0 2.3 0.0 0.2 0.1 0.0 0.0 0.0 1.7 0.0 0.2 0.9 0.1 0.0 9.9 1.2 0.1 0.1 0.1 0.6 0.1 0.0 0.1 0.6 0.4 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 1.3 17.6 0.1 2.8 5.4 0.4 1.0 0.0 0.0 0.0 0.0 4.5 9.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 5.8 0.0 0.0 14.4 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 3.2 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.4 0.2 0.1 0.0 2.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 1.9;Excitatory neurons: 1.6;Fibroblasts: 3.1;Oligodendrocyte precursor cells: 7.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 20.4;LHCN-M2: 33.1;SuSa: 15.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" 1.3 0.1 0.3 0.9 0.3 0.0 0.4 0.4 0.8 0.2 0.0 0.7 0.3 1.4 0.4 0.4 0.5 2.4 2.8 0.3 0.4 0.2 0.4 0.2 0.1 0.8 0.4 0.1 0.7 0.1 0.1 10.9 1.0 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.9 1.1 0.4 0.0 0.6 0.6 0.8 0.1 0.6 0.0 0.0 0.8 0.9 0.4 0.0 0.0 0.2 0.0 1.1 0.6 3.9 2.6 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 3.2 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 3.0 0.0 20.4 0.2 0.0 0.0 0.0 33.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.4 0.8 0.3 0.4 0.8 0.4 1.0 0.4 0.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.8 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 GDF7 BMP12 ENSG00000143869 "Growth differentiation factor 7" Q7Z4P5 2 20667144-20679243 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 9.8;seminal vesicle: 22.4" "Group enriched" "Detected in some" 12 "Endometrial stromal cells: 137.0;Granulosa cells: 83.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.7;Hep G2: 4.4;RT4: 8.3;SH-SY5Y: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA069106 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA069106: " "unprognostic (1.35e-1)" "unprognostic (9.93e-3)" "unprognostic (5.10e-1)" "unprognostic (2.44e-3)" "unprognostic (1.35e-1)" "unprognostic (2.06e-3)" "unprognostic (8.63e-3)" "unprognostic (6.31e-3)" "unprognostic (8.00e-3)" "unprognostic (3.85e-1)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.28e-3)" "unprognostic (8.02e-3)" "unprognostic (2.05e-1)" "unprognostic (3.44e-2)" "unprognostic (1.89e-3)" 0.4 0.4 0.2 1.0 0.5 0.2 0.1 0.0 2.5 9.8 0.0 0.5 0.2 7.2 3.3 0.9 0.7 0.6 0.8 0.4 0.1 3.6 5.0 0.4 2.3 0.3 0.1 0.3 0.6 0.1 0.3 0.8 0.0 3.8 0.2 0.1 0.1 22.4 0.0 1.3 1.6 1.1 0.0 1.3 0.7 0.2 0.3 0.2 0.2 0.6 1.8 1.1 6.6 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 1.2 8.3 0.0 3.3 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.5 0.4 0.1 0.3 0.1 0.0 0.0 0.3 0.6 0.1 6.4 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.5 0.0 0.0 8.8 2.8 3.1 5.5 0.0 0.0 0.1 0.1 1.9 0.1 0.1 3.5 137.0 1.8 0.0 2.7 0.2 0.0 0.1 1.3 0.0 2.9 0.0 83.7 0.0 8.2 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.0 4.1 0.7 0.0 0.0 0.3 7.1 0.5 1.0 0.0 0.0 0.0 0.8 0.0 0.0 1.5 GDF9 ENSG00000164404 "Growth differentiation factor 9" O60383 5 132861181-132866884 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.9" "Cell type enhanced" "Detected in some" "Early spermatids: 19.9;Late spermatids: 5.2;Spermatocytes: 15.2" "Cancer enriched" "Detected in some" 5 "breast cancer: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069146 Supported Approved "Golgi apparatus,Cytosol" "Secreted in female reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" Cytosol "HPA069146: AB_2686094" "unprognostic (4.64e-1)" "unprognostic (1.22e-1)" "unprognostic (1.25e-2)" "unprognostic (5.11e-2)" "unprognostic (1.58e-2)" "unprognostic (2.39e-2)" "unprognostic (1.55e-1)" "unprognostic (4.61e-2)" "unprognostic (4.88e-2)" "unprognostic (1.68e-1)" "unprognostic (6.70e-3)" "unprognostic (1.04e-1)" "unprognostic (1.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (4.75e-3)" "unprognostic (3.10e-2)" 0.3 0.6 1.3 0.2 1.5 0.3 0.8 1.3 2.0 0.4 0.9 0.3 0.4 0.3 4.1 0.3 0.8 0.2 0.3 1.3 1.4 1.4 0.6 0.3 0.5 1.2 1.4 0.5 1.0 0.7 1.7 0.2 1.4 0.6 0.3 1.3 0.8 0.5 0.7 1.0 0.4 0.2 1.4 0.4 1.0 8.9 1.3 0.7 1.0 0.7 0.4 0.6 0.3 1.4 0.2 0.1 0.5 1.1 0.7 0.3 0.1 0.0 0.1 0.1 0.1 0.3 0.8 0.2 0.6 0.1 0.9 0.2 0.4 0.4 0.1 0.4 0.7 0.5 0.5 0.1 0.1 0.1 0.0 0.3 0.6 0.0 0.3 0.1 0.0 3.9 0.0 1.2 0.2 0.2 0.7 0.8 0.2 0.1 0.0 0.6 0.0 0.2 0.3 0.2 1.0 0.9 0.2 0.1 0.5 0.7 0.5 0.1 0.1 0.9 0.4 0.2 0.1 1.3 1.7 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.3 2.0 1.3 1.4 1.2 1.4 1.4 1.4 1.3 1.4 0.9 0.0 0.0 1.6 0.1 0.1 0.4 0.1 0.0 0.4 1.9 2.2 0.6 0.0 0.1 0.0 4.2 0.4 0.3 0.7 3.9 0.1 19.9 1.4 0.9 0.5 0.0 0.0 0.5 0.2 0.3 0.4 0.0 1.9 0.0 0.5 0.4 0.2 0.1 0.0 0.8 0.9 0.0 0.3 0.0 5.2 0.6 0.5 0.0 0.0 0.0 1.0 0.0 2.0 0.9 0.1 0.1 0.4 0.1 0.6 0.3 0.4 0.6 1.0 0.0 1.6 0.8 15.2 2.5 1.1 0.1 0.7 0.2 0.2 0.5 0.2 GDNF "ATF1, ATF2, HFB1-GDNF" ENSG00000168621 "Glial cell derived neurotrophic factor" P39905 5 37812677-37840041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes, Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8.2;skeletal muscle: 10.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 3.3;Skeletal myocytes: 11.5;Spermatogonia: 3.4;Theca cells: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 41.4;SuSa: 12.6;U-87 MG: 12.6;WM-115: 46.5" "Region enhanced" "Detected in single" "basal ganglia: 2.8" "Low region specificity" "Detected in some" "CAB005210, HPA070283" Supported Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Vesicles Nucleoplasm "CAB005210: AB_2247684, HPA070283: AB_2686246" "unprognostic (1.08e-1)" "unprognostic (6.30e-2)" "unprognostic (3.54e-2)" "unprognostic (8.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (5.33e-2)" "unprognostic (1.92e-1)" "unprognostic (3.71e-2)" "unprognostic (2.01e-2)" "unprognostic (2.41e-1)" "unprognostic (2.10e-1)" "unprognostic (1.16e-4)" "unprognostic (2.04e-1)" "unprognostic (8.86e-2)" "unprognostic (1.05e-1)" "unprognostic (4.42e-2)" 0.1 0.4 2.3 1.6 1.5 0.1 0.3 5.8 1.4 0.8 0.0 8.2 1.4 1.3 2.5 0.9 0.9 0.9 0.8 0.6 1.6 0.9 0.7 0.0 0.1 0.7 3.1 3.6 0.0 0.0 0.1 5.0 1.0 1.3 2.4 0.3 0.2 4.5 10.1 1.3 2.0 2.1 0.2 0.4 1.6 0.4 6.1 0.1 0.1 4.3 0.0 0.7 0.8 2.9 0.0 0.0 0.1 0.1 1.8 1.0 0.0 5.5 3.4 1.1 1.6 0.0 0.1 0.1 0.0 7.4 0.1 0.2 0.0 0.1 2.2 0.0 0.2 0.0 0.4 0.5 0.2 0.1 0.1 1.8 0.1 41.4 0.0 1.4 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.1 0.4 0.1 0.0 0.1 9.0 0.0 0.0 0.2 0.5 0.0 0.3 0.2 2.7 12.6 0.1 0.0 0.0 5.5 0.0 1.4 6.2 4.0 0.0 0.0 12.6 0.0 46.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 1.5 5.8 1.4 0.6 1.6 0.7 3.1 1.0 0.2 6.1 2.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 0.6 0.6 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.1 3.3 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 1.5 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.7 0.1 0.0 0.0 11.5 1.8 0.9 3.4 0.0 0.3 0.1 0.0 2.6 0.0 0.5 GET3 "ARSA-I, ASNA1, TRC40" ENSG00000198356 "Guided entry of tail-anchored proteins factor 3, ATPase" O43681 19 12737139-12748323 "Predicted intracellular proteins, Transporters" Transport Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Cytotrophoblasts: 106.6;Extravillous trophoblasts: 80.7;Hofbauer cells: 142.4;Syncytiotrophoblasts: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045951, HPA048087" Approved Enhanced Nucleoplasm,Nucleoli NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoli Nucleoplasm "HPA045951: AB_2679511, HPA048087: AB_2680258" "unprognostic (2.87e-1)" "prognostic favorable (9.53e-4)" "unprognostic (1.01e-1)" "unprognostic (2.16e-1)" "unprognostic (2.05e-2)" "unprognostic (5.70e-2)" "unprognostic (2.01e-2)" "unprognostic (1.33e-2)" "unprognostic (3.34e-1)" "unprognostic (3.08e-2)" "unprognostic (1.85e-1)" "unprognostic (4.39e-2)" "prognostic favorable (4.27e-5)" "unprognostic (6.11e-2)" "unprognostic (5.77e-2)" "unprognostic (2.32e-3)" "prognostic unfavorable (8.47e-4)" 47.5 61.6 56.4 39.4 58.2 66.2 46.5 59.0 72.8 48.4 62.4 43.0 39.9 49.8 41.0 58.1 47.0 39.3 62.0 59.6 58.4 61.6 38.4 40.8 48.3 55.4 57.3 41.9 48.2 73.3 48.2 28.0 57.9 34.3 28.7 36.4 47.3 31.4 67.6 59.1 38.7 33.9 55.9 43.4 50.9 60.2 58.9 46.9 56.3 58.6 38.1 46.3 43.3 57.3 143.7 116.5 60.7 132.3 118.6 72.4 74.6 72.4 99.7 137.5 107.6 90.3 69.6 64.8 111.0 95.4 157.5 75.2 84.5 97.6 65.4 100.9 132.7 54.3 82.4 105.3 125.8 83.5 104.9 83.6 84.1 111.3 66.1 89.2 99.4 75.9 71.3 86.8 109.5 320.4 112.9 68.1 154.6 92.0 215.6 82.2 93.6 128.4 130.2 120.7 111.6 95.5 97.3 131.3 119.8 51.5 108.2 80.5 85.5 193.3 65.4 217.1 172.4 153.9 279.4 61.7 136.2 137.0 109.0 33.6 44.3 26.3 24.8 34.3 21.2 20.3 22.0 22.2 44.8 17.0 15.7 19.5 15.6 16.7 42.9 29.4 34.2 35.8 56.4 58.2 59.0 72.8 59.6 58.4 55.4 57.3 57.9 55.9 58.9 57.3 14.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 106.6 13.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 80.7 12.5 0.0 0.0 0.0 0.0 0.0 0.0 142.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 110.7 1.7 0.0 0.0 0.0 GFAP FLJ45472 ENSG00000131095 "Glial fibrillary acidic protein" P14136 17 44903159-44916937 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 13076.3" "Cell type enriched" "Detected in some" 7 "Astrocytes: 381.9" "Cancer enriched" "Detected in some" 368 "glioma: 2468.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 6.2;NK-cells: 1.7" "Cell line enhanced" "Detected in many" "U-87 MG: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000039, HPA056030, HPA063513" Enhanced Supported Supported "Intermediate filaments" No No 170000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" "Intermediate filaments" "CAB000039: AB_10013382, HPA056030: AB_2683015, HPA063513: AB_2685027" "unprognostic (1.79e-2)" "unprognostic (2.74e-1)" "unprognostic (9.83e-2)" "unprognostic (2.12e-5)" "unprognostic (4.08e-1)" "unprognostic (5.09e-1)" "unprognostic (1.26e-1)" "unprognostic (6.53e-2)" "unprognostic (6.57e-3)" "unprognostic (7.35e-2)" "unprognostic (5.86e-2)" "unprognostic (1.24e-1)" "unprognostic (7.63e-2)" "unprognostic (2.75e-5)" "unprognostic (1.49e-1)" "unprognostic (1.66e-1)" "unprognostic (1.64e-1)" 1.9 1.8 5096.2 2.2 5407.4 14.1 3.5 5902.8 4887.4 1.9 2342.2 1.4 0.4 0.9 1.5 3.7 2.2 1.6 8.2 5059.3 9869.7 2.1 1.7 1.3 1.9 13076.3 9001.4 2.1 1.5 1.6 33.9 0.7 9204.1 1.3 1.0 117.7 1.9 1.0 2.1 2.6 0.7 0.9 10040.2 1.5 1.5 1.4 8068.5 0.4 1.7 0.3 1.1 1.4 0.9 10496.9 1.0 0.7 1.2 2.3 0.0 0.4 0.2 1.0 1.2 1.5 1.2 1.3 1.5 2.2 1.9 0.5 0.9 2.7 1.4 0.4 1.8 3.0 1.1 1.4 2.1 0.9 0.0 0.2 2.2 0.1 0.8 1.0 0.0 1.7 0.0 2.3 0.7 5.3 0.8 1.3 1.9 2.6 1.6 0.1 3.3 0.7 0.7 1.2 0.7 0.6 1.6 1.8 0.1 1.7 0.2 1.0 1.2 1.2 0.7 1.2 0.9 1.1 2.0 0.7 1.6 1.6 6.1 2.0 2.7 1.5 0.8 0.3 0.3 0.6 0.2 0.2 0.2 0.4 0.1 0.5 0.3 0.4 6.2 1.7 0.5 0.5 0.2 0.2 5096.2 5407.4 5902.8 4887.4 5059.3 9869.7 13076.3 9001.4 9204.1 10040.2 8068.5 10496.9 0.0 0.0 0.0 381.9 0.1 0.0 0.1 0.0 0.0 0.8 1.3 0.6 5.2 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.8 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.7 0.0 53.5 0.0 10.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4.4 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 GFOD2 "FLJ23802, MGC11335" ENSG00000141098 "Glucose-fructose oxidoreductase domain containing 2" Q3B7J2 16 67674531-67719339 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040939, HPA041112" Uncertain Supported Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA040939: AB_10796564, HPA041112: AB_10794541" "unprognostic (9.80e-2)" "unprognostic (2.20e-1)" "unprognostic (2.06e-2)" "unprognostic (3.16e-3)" "unprognostic (4.62e-2)" "unprognostic (1.38e-1)" "unprognostic (2.93e-2)" "unprognostic (5.61e-3)" "unprognostic (1.19e-1)" "unprognostic (2.22e-2)" "prognostic favorable (5.95e-4)" "unprognostic (1.17e-1)" "prognostic favorable (8.66e-4)" "unprognostic (1.90e-1)" "unprognostic (1.76e-1)" "unprognostic (7.87e-2)" "unprognostic (9.64e-2)" 12.5 12.2 13.4 6.9 13.8 16.6 12.6 27.4 14.8 17.6 13.4 11.8 11.7 10.8 5.5 33.5 13.0 7.9 7.2 13.0 13.9 12.4 40.8 9.3 8.7 11.3 12.9 6.4 8.9 12.0 13.2 14.7 13.6 10.9 9.3 8.1 12.7 7.3 9.2 16.7 9.2 9.2 8.8 18.5 8.0 11.1 12.6 8.1 10.3 7.1 12.9 10.9 26.3 11.5 15.8 25.1 15.1 31.0 14.9 11.3 18.1 12.7 16.5 23.3 23.9 21.5 13.9 26.6 11.8 14.8 12.6 19.4 15.6 14.9 19.3 16.2 20.1 6.7 14.5 30.4 11.4 11.0 12.5 9.1 16.9 31.0 9.2 11.7 34.5 26.9 14.1 4.9 13.2 33.0 18.2 13.4 20.7 9.4 13.8 28.7 8.9 20.8 14.5 21.5 30.4 18.4 31.6 10.5 9.6 8.7 15.9 7.3 26.4 17.8 18.1 16.3 13.0 13.2 19.8 29.0 11.1 15.8 13.3 0.5 4.8 5.2 4.4 2.9 7.2 6.3 7.7 7.9 4.8 7.0 6.6 5.3 9.0 5.9 3.1 5.4 9.2 3.7 13.4 13.8 27.4 14.8 13.0 13.9 11.3 12.9 13.6 8.8 12.6 11.5 36.1 0.0 8.4 8.5 7.7 22.9 15.8 8.1 15.9 13.7 21.7 12.4 5.3 15.7 10.9 11.0 14.6 10.3 10.6 23.8 5.9 21.1 89.6 22.5 10.9 33.8 43.2 56.6 18.3 11.6 24.1 10.4 3.6 8.7 4.5 12.2 31.1 46.7 6.6 21.9 16.8 17.0 16.2 7.5 10.0 29.9 8.7 4.6 8.8 6.5 5.2 12.0 11.3 8.5 7.3 15.8 14.2 11.3 9.1 12.4 20.6 13.0 24.5 11.0 6.6 11.9 11.4 19.9 14.8 10.1 27.3 22.2 10.3 9.3 18.3 21.3 GFRA2 "GDNFRB, NTNRA, RETL2, TRNR2" ENSG00000168546 "GDNF family receptor alpha 2" O00451 8 21690398-21812357 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.4;thyroid gland: 8.7" "Group enriched" "Detected in some" 4 "Early spermatids: 91.9;Horizontal cells: 220.4;Late spermatids: 238.1" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 6.2" "Region enhanced" "Detected in many" "cerebral cortex: 5.0" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 9.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.5;monocytes: 9.2" "Cell line enhanced" "Detected in some" "HEL: 9.1;HMC-1: 21.4;WM-115: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024704, CAB032791" Uncertain Approved Vesicles "Intracellular and membrane" NA NA 9000000 "Cluster 7: Monocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB032791: AB_2110428, HPA024704: AB_1849629" "unprognostic (4.24e-2)" "unprognostic (1.11e-2)" "unprognostic (4.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.93e-2)" "unprognostic (1.08e-2)" "unprognostic (7.48e-4)" "unprognostic (2.87e-1)" "unprognostic (6.11e-2)" "unprognostic (4.40e-3)" "unprognostic (2.11e-3)" "unprognostic (7.82e-2)" "unprognostic (1.50e-4)" "unprognostic (8.45e-4)" "unprognostic (1.74e-1)" "unprognostic (4.68e-2)" "unprognostic (9.63e-3)" 2.4 1.8 1.2 2.0 1.0 0.6 0.6 0.0 5.0 2.6 0.0 2.1 1.9 0.5 0.2 1.5 1.3 0.6 1.0 1.5 2.2 0.2 0.9 1.2 1.6 0.0 0.8 0.3 0.3 0.1 0.4 7.1 0.0 0.4 1.1 2.6 0.9 1.5 0.1 0.5 1.8 2.0 0.0 7.5 1.0 9.4 1.8 1.1 8.7 0.6 0.8 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.9 0.8 0.0 9.2 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.4 0.0 1.3 0.0 0.0 0.9 1.2 1.0 0.0 5.0 1.5 2.2 0.0 0.8 0.0 0.0 1.8 0.0 0.3 0.0 1.8 1.3 0.1 1.8 0.2 0.0 0.0 4.3 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 91.9 0.0 1.2 0.3 0.0 0.0 39.5 0.0 0.1 1.8 0.0 0.1 1.3 0.0 0.7 0.2 0.6 220.4 6.5 0.0 0.0 30.6 25.2 238.1 0.6 11.8 0.0 3.7 0.5 1.9 0.0 2.5 1.1 0.0 0.0 1.9 0.1 0.1 0.0 0.0 0.0 2.1 6.6 0.7 1.8 1.2 7.0 0.0 0.9 0.3 0.2 0.1 0.0 0.1 GFRA4 ENSG00000125861 "GDNF family receptor alpha 4" Q9GZZ7 20 3659248-3663399 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "thyroid gland: 1.1" "Cell type enhanced" "Detected in some" "Early spermatids: 1.6;Late spermatids: 3.2;Proximal tubular cells: 1.3" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 43: Testis - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (3.50e-2)" "unprognostic (2.36e-1)" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.3 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GGA2 "KIAA1080, VEAR" ENSG00000103365 "Golgi associated, gamma adaptin ear containing, ARF binding protein 2" Q9UJY4 16 23463542-23521995 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 153.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 159.9;U-698: 170.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB034422, HPA043313, HPA063634" Approved Enhanced "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "CAB034422: AB_2110748, HPA043313: AB_2678421, HPA063634: AB_2685067" "unprognostic (1.27e-1)" "prognostic favorable (1.71e-5)" "unprognostic (8.53e-2)" "unprognostic (2.22e-2)" "unprognostic (4.91e-2)" "prognostic favorable (9.70e-5)" "unprognostic (1.68e-1)" "prognostic favorable (1.68e-4)" "unprognostic (7.82e-3)" "unprognostic (3.88e-2)" "unprognostic (2.15e-3)" "unprognostic (8.55e-2)" "prognostic favorable (3.91e-5)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.15e-4)" "unprognostic (3.89e-2)" "unprognostic (2.08e-1)" 15.1 36.3 13.0 32.0 13.1 37.6 19.9 18.6 14.8 20.7 25.2 16.5 10.0 16.1 19.6 17.9 18.4 13.4 18.5 13.8 15.3 26.9 16.4 34.1 72.9 11.7 12.9 34.0 54.3 29.2 26.0 17.6 11.9 27.4 15.8 79.3 37.6 21.3 25.5 21.1 33.6 14.9 10.8 44.2 25.7 12.4 17.8 37.2 36.2 19.0 87.3 16.3 18.7 12.3 18.8 22.9 29.6 26.1 16.5 17.9 25.3 19.7 20.0 15.2 19.3 32.1 18.9 159.9 31.4 21.1 4.3 28.7 49.1 25.8 19.4 25.1 45.6 28.8 29.5 51.2 16.2 48.0 18.2 18.7 22.7 20.8 9.7 22.1 22.0 12.8 50.3 23.0 19.8 29.8 17.0 31.9 39.6 18.3 20.2 108.3 38.4 41.2 24.8 25.6 21.1 25.3 18.3 27.0 27.1 31.5 23.7 59.7 24.5 18.1 19.6 20.3 18.5 42.0 41.8 170.8 16.5 32.2 20.6 0.2 4.2 7.0 3.1 4.3 3.2 16.2 3.9 3.7 4.9 21.6 4.0 4.0 0.5 3.1 4.0 15.9 4.5 3.1 13.0 13.1 18.6 14.8 13.8 15.3 11.7 12.9 11.9 10.8 17.8 12.3 11.7 48.1 41.4 28.7 102.3 34.2 33.6 16.5 39.3 73.2 25.0 26.0 27.3 21.5 17.6 22.0 114.7 23.0 80.6 7.3 25.4 19.3 22.0 25.4 17.6 19.0 17.6 9.9 44.2 18.9 40.7 17.3 15.3 37.3 9.5 88.5 12.5 16.1 69.1 6.7 61.5 12.6 12.2 26.1 19.7 30.8 24.5 37.7 26.6 36.5 87.9 23.8 23.7 26.2 8.3 16.2 6.1 26.4 36.1 20.7 8.7 21.5 16.2 153.3 19.7 16.0 16.3 30.5 60.5 25.4 14.6 22.7 34.8 56.8 11.9 18.6 GGH ENSG00000137563 "Gamma-glutamyl hydrolase" Q92820 8 63014881-63039407 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 125.7;liver: 188.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 510.3;Early spermatids: 471.0;Extravillous trophoblasts: 273.4;Proximal tubular cells: 340.8;Syncytiotrophoblasts: 754.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 30.6" "Lineage enriched" "Detected in all" 5 "dendritic cells: 30.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019296, HPA025226" Approved "Intracellular and membrane" NA NA 1200000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB019296: , HPA025226: AB_1849645" "unprognostic (9.29e-2)" "unprognostic (1.22e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.99e-7)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (1.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.11e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-2)" "unprognostic (9.62e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (6.50e-2)" 9.8 5.4 11.1 14.2 11.1 43.7 16.5 10.7 14.3 5.9 13.1 54.3 11.3 6.3 4.4 20.7 3.5 4.3 3.1 11.1 12.3 125.7 188.6 8.0 10.9 13.3 11.1 3.1 9.9 13.1 1.9 54.9 13.7 4.4 74.4 2.1 13.0 3.7 2.1 27.2 9.9 11.6 10.1 5.5 8.2 33.9 14.4 17.8 2.4 3.2 22.5 8.5 10.8 11.1 110.5 97.6 97.4 15.7 94.1 39.6 69.6 64.3 105.1 94.2 137.7 144.5 183.8 69.8 18.0 77.1 166.8 87.2 97.2 101.9 138.9 139.0 71.6 112.3 50.3 105.1 17.6 53.5 65.9 29.1 29.2 93.9 50.7 59.4 116.1 66.9 62.4 255.2 177.3 64.3 28.8 71.1 51.0 231.6 86.0 77.6 95.2 98.1 75.8 40.3 38.6 69.9 91.8 103.6 98.5 91.6 116.6 65.8 65.5 104.2 115.6 99.4 111.3 112.6 127.2 88.3 158.0 0.1 185.0 0.0 2.1 2.3 1.1 1.7 0.8 6.5 1.5 1.7 0.9 2.7 1.8 1.9 3.0 4.4 2.0 30.6 2.7 1.9 11.1 11.1 10.7 14.3 11.1 12.3 13.3 11.1 13.7 10.1 14.4 11.1 13.1 16.0 7.3 11.1 26.1 30.2 23.2 66.6 9.1 2.0 14.9 21.0 3.2 17.2 31.1 22.0 0.0 510.3 11.7 49.2 37.2 19.7 471.0 5.4 11.5 13.1 13.2 62.5 11.5 7.4 273.4 27.2 11.7 7.6 10.8 21.4 13.6 219.5 72.4 0.0 8.7 70.7 44.7 21.0 15.5 154.2 5.9 12.0 24.9 1.0 32.1 23.1 2.1 3.5 2.9 4.3 23.7 8.2 106.9 10.5 4.3 340.8 18.3 1.3 26.3 12.8 20.4 80.3 133.0 35.9 43.0 754.5 8.5 9.3 102.0 23.1 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 174.8;liver: 115.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.1;Cholangiocytes: 48.6;Distal enterocytes: 54.1;Ductal cells: 82.6;Hepatocytes: 40.8;Proximal enterocytes: 111.7;Proximal tubular cells: 62.9" "Cancer enhanced" "Detected in all" "renal cancer: 37.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 103.6;Karpas-707: 165.8;OE19: 169.5;RPMI-8226: 210.3;RPTEC TERT1: 203.2" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 3.3 2.4 5.5 6.4 6.7 12.0 24.7 7.0 7.5 28.7 5.1 20.3 84.7 3.0 72.0 3.3 3.3 47.1 7.2 5.1 5.1 174.8 115.7 42.6 5.4 7.2 6.6 3.2 63.1 0.2 5.5 2.4 7.8 48.8 11.0 1.6 9.9 21.6 1.9 4.1 80.4 2.2 5.9 13.3 31.3 18.4 7.1 6.5 15.9 0.4 6.2 5.7 4.3 9.2 1.0 79.7 1.0 0.3 0.0 0.5 2.2 0.5 1.7 0.8 1.0 11.7 18.3 1.0 16.2 0.1 14.8 11.0 6.2 0.8 0.5 103.6 12.3 0.6 40.8 64.3 5.5 1.5 33.2 2.1 0.9 2.5 1.7 1.4 0.5 19.0 8.4 165.8 1.0 1.7 1.6 52.4 6.4 169.5 0.7 0.7 6.8 210.3 203.2 2.9 0.5 1.2 0.4 33.3 0.8 22.2 32.4 39.6 6.4 10.6 9.3 46.6 0.9 48.2 18.4 0.7 19.0 58.7 0.5 4.8 12.3 0.2 1.0 6.0 2.9 2.2 5.0 2.4 6.5 0.2 0.6 1.4 15.9 4.9 4.0 0.1 6.5 5.6 5.5 6.7 7.0 7.5 5.1 5.1 7.2 6.6 7.8 5.9 7.1 9.2 0.2 80.1 22.8 3.3 2.8 0.8 0.1 0.3 4.6 0.5 5.9 2.3 0.7 48.6 4.9 1.8 0.0 1.4 0.7 54.1 1.9 82.6 1.8 1.2 0.6 0.7 1.2 5.3 4.4 8.1 0.4 3.9 15.3 5.1 5.7 0.1 1.8 40.8 4.9 0.0 4.1 4.4 4.1 2.5 1.7 6.7 0.0 2.9 1.8 1.0 5.8 2.5 0.0 1.5 5.7 20.9 20.1 0.4 12.8 2.0 111.7 62.9 1.6 0.1 0.0 0.1 1.0 0.6 0.8 0.4 0.4 0.8 4.0 0.0 6.5 0.1 GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 42.8;Fibroblasts: 58.3;Leydig cells: 36.4;Sertoli cells: 184.1;Smooth muscle cells: 85.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3;eosinophil: 4.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 164.9;ASC TERT1: 124.4;HHSteC: 234.7;HSkMC: 271.7;TIME: 110.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" NA NA 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (6.36e-5)" "prognostic unfavorable (4.06e-4)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" 137.6 60.5 39.0 18.6 39.3 1.4 90.6 37.6 41.7 73.2 32.8 27.8 19.4 54.4 12.9 19.6 70.6 37.2 93.4 35.0 45.1 78.2 55.2 37.7 48.0 52.2 46.3 26.6 25.8 13.2 41.1 11.9 46.9 49.3 12.0 2.1 37.1 20.9 23.1 40.1 40.8 32.2 41.9 36.1 40.0 9.6 45.3 10.4 110.2 16.6 18.3 45.1 64.2 38.2 0.0 1.8 0.6 0.0 164.9 124.4 1.1 2.9 0.2 0.1 0.0 0.1 0.1 0.2 3.4 0.2 0.3 0.3 0.1 0.1 0.0 2.2 0.9 6.7 1.0 24.1 234.7 3.0 6.4 271.7 0.1 3.4 3.2 0.4 45.8 0.7 0.4 1.2 44.1 0.4 0.0 22.4 3.6 1.1 0.0 0.1 4.0 1.0 6.1 0.0 0.4 5.9 0.1 7.3 0.1 22.7 1.0 1.7 110.8 0.1 2.3 0.1 0.0 0.3 1.5 0.2 3.9 5.7 0.2 2.3 0.5 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.2 39.0 39.3 37.6 41.7 35.0 45.1 52.2 46.3 46.9 41.9 45.3 38.2 27.2 3.2 16.0 1.0 0.3 7.0 3.3 3.2 0.0 0.0 7.2 4.2 4.4 0.0 17.9 0.0 0.0 0.2 0.4 0.0 0.0 0.6 0.8 0.3 8.3 42.8 0.0 2.7 0.1 0.2 0.2 58.3 1.1 0.4 1.3 0.0 33.5 0.1 2.1 0.0 0.1 0.0 0.0 1.0 12.5 3.3 36.4 1.8 3.6 22.5 3.3 0.3 0.0 0.5 0.0 0.4 0.0 23.7 0.3 2.2 0.0 0.1 2.2 1.0 184.1 33.9 85.6 0.6 0.4 0.3 4.4 0.3 1.1 2.1 0.0 1.4 GGTA1 "GGTA, GGTA1P, GLYT2" ENSG00000204136 "Glycoprotein alpha-galactosyltransferase 1 (inactive)" Q4G0N0 9 121444991-121499844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 133.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Endothelial cells: 2.2;granulocytes: 3.8;Macrophages: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 22.7;intermediate monocyte: 17.9;myeloid DC: 12.7;plasmacytoid DC: 27.5" "Group enriched" "Detected in many" 19 "dendritic cells: 27.5;monocytes: 22.7" "Group enriched" "Detected in some" 6 "AN3-CA: 4.3;HEL: 1.3;SH-SY5Y: 4.9" HPA023262 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "HPA023262: AB_1849651" "unprognostic (1.71e-1)" "unprognostic (9.98e-2)" "unprognostic (4.49e-2)" "prognostic favorable (5.33e-5)" "unprognostic (1.67e-2)" "unprognostic (2.85e-2)" "unprognostic (8.98e-2)" "unprognostic (1.34e-2)" "unprognostic (2.43e-1)" "unprognostic (1.29e-1)" "unprognostic (7.85e-2)" "unprognostic (1.63e-1)" "unprognostic (5.53e-3)" "unprognostic (9.24e-2)" "unprognostic (2.64e-2)" "unprognostic (1.44e-2)" "unprognostic (6.87e-2)" 33.4 18.5 15.4 10.1 18.9 68.2 40.4 12.7 19.9 17.2 14.4 14.9 12.0 10.7 7.4 24.2 10.1 23.1 18.7 16.4 15.3 5.7 15.0 21.9 25.7 13.9 15.2 7.6 5.0 4.8 41.7 13.7 6.5 15.4 0.5 133.2 15.3 5.0 13.6 16.1 12.5 14.1 40.4 8.7 4.1 16.0 9.9 5.1 13.4 10.4 21.4 14.9 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.7 0.0 0.0 17.9 0.0 0.7 0.0 0.0 12.7 0.0 0.0 0.0 1.2 0.1 0.4 27.5 0.0 7.2 15.4 18.9 12.7 19.9 16.4 15.3 13.9 15.2 13.7 14.1 16.0 14.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 GH1 "GH, GH-N, GHN, hGH-N" ENSG00000259384 "Growth hormone 1" P01241 17 63917200-63918839 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 868 "pituitary gland: 59365.3" "Cell type enhanced" "Detected in single" "Adipocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043715 Supported "Secreted to blood" NA NA 2690000 6400000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 57: B-cells - Immune response" "HPA043715: AB_2678632" "unprognostic (1.91e-2)" "unprognostic (3.51e-2)" "unprognostic (1.72e-2)" "unprognostic (2.98e-1)" "unprognostic (9.45e-4)" "unprognostic (2.48e-1)" "unprognostic (2.09e-4)" "unprognostic (2.03e-2)" "unprognostic (6.57e-2)" "unprognostic (2.33e-1)" 14.8 68.3 0.1 0.0 0.1 0.1 2.1 0.1 0.6 1.9 0.1 3.7 0.5 4.1 0.0 9.5 2.8 0.0 7.8 0.1 0.4 4.1 18.4 3.5 0.0 0.1 0.1 6.1 7.7 0.0 59365.3 0.8 0.1 5.5 0.0 0.0 4.8 0.0 3.5 36.2 3.9 0.0 0.1 7.7 11.8 7.2 0.1 0.3 5.4 0.1 0.0 1.5 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.6 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.0 GH2 "GH-V, GHL, GHV, hGH-V" ENSG00000136487 "Growth hormone 2" P01242 17 63880215-63881944 "Cancer-related genes, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 79 "pituitary gland: 102.4;placenta: 127.5" "Group enriched" "Detected in some" 23 "Extravillous trophoblasts: 8.6;Syncytiotrophoblasts: 23.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "BEWO: 8.4" HPA043715 Supported "Secreted to blood" NA NA 4200000 "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA043715: AB_2678632" "unprognostic (1.02e-1)" 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 102.4 127.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 23.7 0.0 0.0 0.0 0.0 GHDC LGP1 ENSG00000167925 "GH3 domain containing" Q8N2G8 17 42188799-42194532 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031650 Uncertain "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA031650: AB_10601014" "unprognostic (2.30e-2)" "unprognostic (1.63e-1)" "unprognostic (2.60e-1)" "prognostic favorable (3.21e-4)" "prognostic unfavorable (6.81e-5)" "unprognostic (5.13e-2)" "unprognostic (3.35e-2)" "unprognostic (2.56e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (5.20e-4)" "unprognostic (6.69e-3)" "unprognostic (5.18e-2)" "prognostic favorable (2.00e-6)" "unprognostic (2.08e-1)" "unprognostic (7.93e-2)" "unprognostic (9.66e-2)" "unprognostic (4.02e-2)" 15.7 32.9 14.3 10.1 15.2 11.8 15.8 15.1 16.2 18.6 15.2 15.3 15.8 15.1 11.0 8.8 15.9 10.6 12.3 13.9 15.8 24.5 18.6 15.9 13.2 18.3 15.7 22.2 26.4 12.8 16.7 9.3 16.7 20.7 5.3 3.8 24.1 14.2 7.8 9.8 19.4 5.3 15.0 32.2 19.5 5.9 15.5 7.4 26.8 5.7 6.5 15.5 13.3 16.3 7.5 26.1 1.8 20.5 6.8 6.0 16.1 9.9 7.7 5.0 6.5 8.4 35.4 11.4 34.9 9.2 6.1 0.6 5.8 0.2 1.2 18.8 21.1 17.3 11.9 18.0 17.7 13.9 70.4 9.1 5.3 13.7 4.2 6.1 7.8 6.9 16.8 50.0 2.6 9.2 9.0 27.1 4.4 28.1 0.0 8.7 9.5 49.8 13.8 6.0 4.0 13.9 0.3 46.1 34.4 0.4 31.8 22.0 6.7 23.3 9.2 20.4 4.7 37.3 31.3 7.7 19.7 17.3 9.6 0.8 3.2 1.8 2.3 3.0 1.0 2.5 1.5 2.3 2.7 4.1 1.5 1.8 1.6 1.1 4.1 2.4 1.4 2.6 14.3 15.2 15.1 16.2 13.9 15.8 18.3 15.7 16.7 15.0 15.5 16.3 16.2 0.0 9.6 4.9 9.9 2.9 9.3 8.8 2.2 7.6 8.8 7.1 2.1 14.3 6.7 16.5 6.2 13.1 8.7 5.1 3.9 12.9 1.0 5.6 8.5 12.6 13.8 4.6 2.6 19.3 11.6 10.0 6.1 8.9 13.3 6.5 28.5 15.3 27.9 8.4 4.3 10.7 8.2 25.5 5.4 1.3 11.5 12.6 8.8 2.8 9.3 16.2 13.4 1.0 3.5 10.3 4.8 13.9 4.7 6.5 25.6 16.5 7.8 5.5 0.0 12.8 6.3 2.8 0.5 2.2 1.8 7.3 9.5 15.9 9.4 5.4 GHRH GHRF ENSG00000118702 "Growth hormone releasing hormone" P01286 20 37251086-37261814 "Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 199.5" "Cell type enriched" "Detected in single" 7 "Cardiomyocytes: 5.2" "Cancer enriched" "Detected in some" 7 "urothelial cancer: 8.5" "Region enriched" "Detected in some" 12 "hypothalamus: 199.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "NTERA-2: 2.1;U-266/84: 7.9" "Region enriched" "Detected in many" 9 "hypothalamus: 32.9" "Region enhanced" "Detected in some" "hypothalamus: 3.7" "Secreted in other tissues" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (4.78e-2)" "unprognostic (2.57e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-1)" 0.0 1.0 0.6 0.0 0.3 0.0 0.3 0.4 0.5 0.0 0.2 0.0 3.4 0.0 0.0 0.3 0.0 0.0 12.5 0.4 199.5 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.3 0.0 0.6 0.1 17.1 9.2 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.4 0.5 0.4 199.5 0.3 0.4 0.3 0.3 17.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 GHRHR ENSG00000106128 "Growth hormone releasing hormone receptor" Q02643 7 30938669-30993254 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 351 "pituitary gland: 211.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.5;Spermatocytes: 1.2;Spermatogonia: 3.0" "Cancer enhanced" "Detected in single" "liver cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "unprognostic (8.32e-2)" "unprognostic (1.45e-1)" "unprognostic (9.30e-2)" "unprognostic (1.39e-1)" "unprognostic (7.23e-2)" "unprognostic (4.15e-1)" "unprognostic (2.28e-2)" "unprognostic (1.54e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (1.43e-2)" "unprognostic (1.47e-1)" "unprognostic (5.87e-3)" 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 211.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.1 1.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GHRL "ghrelin, MTLRP, obestatin" ENSG00000157017 "Ghrelin and obestatin prepropeptide" Q9UBU3 3 10285666-10292947 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "stomach 1: 356.1" "Cell type enriched" "Detected in many" 52 "Gastric mucus-secreting cells: 1123.8" "Cancer enhanced" "Detected in some" "stomach cancer: 3.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 17.5;classical monocyte: 11.0;eosinophil: 12.4;myeloid DC: 41.8;neutrophil: 25.7;plasmacytoid DC: 28.5" "Group enriched" "Detected in many" 6 "dendritic cells: 41.8;granulocytes: 25.7;monocytes: 11.0" "Cell line enhanced" "Detected in many" "Karpas-707: 14.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA014246, CAB022731" Enhanced "Secreted to blood" NA NA 2580000 350000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB022731: , HPA014246: AB_1849659" "unprognostic (1.74e-2)" "unprognostic (3.01e-4)" "unprognostic (3.75e-1)" "unprognostic (1.05e-2)" "unprognostic (2.94e-2)" "unprognostic (1.60e-3)" "unprognostic (2.12e-1)" "unprognostic (1.06e-3)" "unprognostic (3.85e-1)" "unprognostic (5.45e-3)" "unprognostic (1.54e-3)" "unprognostic (2.71e-2)" "unprognostic (1.64e-3)" "unprognostic (4.52e-2)" "unprognostic (8.56e-2)" "unprognostic (2.14e-1)" "unprognostic (1.79e-4)" 0.5 0.5 3.5 3.1 4.1 4.4 1.5 4.0 7.6 0.5 3.0 2.2 19.0 0.7 4.8 1.8 0.7 2.3 1.3 3.3 2.8 0.9 1.4 1.0 7.4 3.2 2.8 1.3 4.1 0.7 0.7 0.5 3.5 1.0 0.6 2.0 1.4 0.3 2.0 2.1 3.1 0.9 2.0 2.5 356.1 1.1 2.7 1.3 1.3 0.2 3.1 1.4 0.5 2.9 0.6 0.2 2.6 2.0 1.8 0.0 4.8 2.4 0.0 0.7 0.2 2.9 0.5 1.5 0.9 0.1 2.1 0.4 0.0 0.6 0.0 0.4 2.9 3.1 2.1 6.3 0.0 3.2 5.3 0.3 0.0 0.0 0.1 0.2 0.5 1.9 1.3 14.4 0.0 0.7 1.2 4.3 1.3 0.5 5.3 0.8 0.2 0.8 0.0 2.4 1.9 0.3 1.6 1.1 0.1 1.7 1.1 3.8 2.6 1.2 0.7 1.1 1.7 1.7 2.6 2.9 0.4 3.5 0.5 17.5 11.0 12.4 0.2 5.5 0.1 2.1 0.2 0.0 41.8 1.0 0.3 0.1 25.7 4.4 0.4 28.5 0.2 3.8 3.5 4.1 4.0 7.6 3.3 2.8 3.2 2.8 3.5 2.0 2.7 2.9 0.6 0.0 1.1 1.3 4.9 1.3 4.6 0.2 0.0 7.8 0.8 0.6 0.3 0.0 0.2 1.8 10.4 1.7 10.5 0.5 0.0 1.0 0.3 0.2 0.7 1.5 0.0 0.0 1.0 1.3 1.5 1.0 1123.8 0.8 0.0 0.6 1.8 0.1 1.8 3.3 0.6 0.1 0.0 3.8 8.8 1.0 0.3 5.7 1.8 2.8 7.4 2.2 21.6 0.0 0.7 0.9 0.1 0.4 0.7 4.9 1.5 0.2 0.2 9.1 6.6 4.0 0.9 1.7 1.3 0.0 0.6 0.3 4.0 0.7 0.8 2.2 GIMAP2 "DKFZp586D0824, HIMAP2, IAN12, IMAP2" ENSG00000106560 "GTPase, IMAP family member 2" Q9UG22 7 150685697-150693641 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 45.0;Kupffer cells: 132.3;monocytes: 74.4;NK-cells: 96.8;T-cells: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 62.7;JURKAT: 34.9;MOLT-4: 79.5;REH: 34.0;U-937: 32.4" "Not detected" "Not detected" "HPA013589, HPA014746" Approved Supported "Nucleoplasm,Lipid droplets" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Lipid droplets" Nucleoplasm "HPA013589: AB_1849666, HPA014746: " "prognostic favorable (3.50e-4)" "unprognostic (4.73e-2)" "unprognostic (2.53e-1)" "unprognostic (3.56e-3)" "unprognostic (6.60e-2)" "unprognostic (6.64e-3)" "unprognostic (4.60e-2)" "unprognostic (5.97e-2)" "unprognostic (3.39e-2)" "unprognostic (3.91e-1)" "unprognostic (5.52e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.54e-1)" "unprognostic (1.88e-2)" "unprognostic (2.56e-2)" "unprognostic (3.08e-2)" 11.7 6.9 6.7 40.3 6.6 11.6 11.9 7.1 9.7 10.6 6.5 11.8 12.4 10.7 8.9 4.9 8.3 17.0 8.0 6.3 6.9 6.0 17.0 22.0 78.4 9.2 7.4 16.9 2.1 2.7 2.6 19.6 8.5 5.0 15.7 0.5 6.5 6.2 4.2 5.8 19.4 11.4 8.3 62.1 11.9 1.8 7.4 50.2 6.1 12.3 57.4 15.7 5.2 8.7 1.6 0.0 0.0 0.0 0.6 0.6 0.8 0.0 18.1 2.2 5.1 0.0 23.7 4.2 0.4 1.4 9.8 1.0 0.0 1.0 0.2 19.8 0.0 12.8 0.0 0.5 2.8 9.9 12.6 6.8 1.8 1.7 0.1 5.3 62.7 34.9 0.4 4.9 1.0 0.0 79.5 24.9 0.0 0.0 0.0 34.0 0.6 9.7 0.1 5.9 0.0 0.0 0.1 0.1 6.3 0.0 0.9 25.2 14.2 0.9 0.3 0.2 0.1 5.6 5.5 0.0 2.3 32.4 3.4 15.1 83.8 7.3 93.9 118.3 118.3 15.8 122.0 114.8 47.6 15.8 166.7 124.8 40.7 136.2 121.4 5.7 107.6 130.2 6.7 6.6 7.1 9.7 6.3 6.9 9.2 7.4 8.5 8.3 7.4 8.7 15.5 12.8 2.2 1.0 11.8 3.3 1.9 0.6 1.2 0.1 1.7 1.3 1.1 1.5 1.1 0.0 0.0 0.4 22.8 1.5 0.0 1.6 0.0 3.8 3.8 27.8 0.0 13.5 0.1 0.7 0.7 3.4 1.1 1.1 19.7 1.4 45.0 4.2 38.1 0.0 0.2 4.2 6.1 132.3 11.1 0.1 4.1 38.5 1.8 7.5 74.4 0.9 96.8 2.0 0.3 1.0 2.9 0.7 4.0 2.2 8.4 1.2 4.6 0.1 6.6 1.7 1.1 0.1 0.3 0.5 3.1 0.4 57.7 4.8 3.7 2.5 GIP ENSG00000159224 "Gastric inhibitory polypeptide" P09681 17 48958554-48968596 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 209 "intestine: 259.5" "Cell type enriched" "Detected in single" 4 "Intestinal goblet cells: 1.9" "Cancer enriched" "Detected in some" 63 "testis cancer: 74.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A549: 6.6;BEWO: 5.9;Hep G2: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021612, HPA064596" Enhanced "Secreted to blood" NA NA 33900 540000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "HPA021612: AB_1849506, HPA064596: " "unprognostic (2.95e-1)" "unprognostic (2.70e-3)" "unprognostic (4.42e-2)" "unprognostic (1.82e-1)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 259.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 93.7 0.0 0.0 0.0 1.2 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.1 0.0 0.3 0.5 5.9 0.3 0.0 0.0 0.0 1.7 0.7 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 9.8 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GKAP1 "FKSG21, GKAP42" ENSG00000165113 "G kinase anchoring protein 1" Q5VSY0 9 83739425-83829516 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 50.1;testis: 199.5" "Group enriched" "Detected in all" 6 "Early spermatids: 1339.6;Late spermatids: 481.5;Spermatocytes: 642.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/84: 34.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035117, HPA035118, HPA066173" Enhanced Supported Approved "Centriolar satellite,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" "Centriolar satellite, Cytosol" "HPA035117: AB_2674473, HPA035118: AB_10671100, HPA066173: AB_2732740" "unprognostic (1.91e-1)" "unprognostic (2.94e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (9.62e-2)" "unprognostic (2.50e-1)" "unprognostic (2.52e-3)" "unprognostic (7.66e-3)" "unprognostic (3.04e-1)" "unprognostic (1.86e-2)" "prognostic favorable (6.96e-5)" "unprognostic (4.18e-1)" "prognostic favorable (1.05e-6)" "unprognostic (9.73e-2)" "unprognostic (1.38e-2)" "unprognostic (2.06e-1)" "unprognostic (6.24e-3)" 7.9 6.4 18.5 2.7 20.3 3.9 6.2 26.9 23.5 8.2 25.7 12.1 4.3 8.8 6.7 3.7 8.2 5.0 14.9 17.0 19.9 7.4 9.4 4.2 3.9 19.2 19.3 12.9 8.4 10.3 12.5 2.4 19.6 8.8 3.5 22.5 5.2 9.0 50.1 2.0 5.3 6.1 19.4 4.1 7.6 199.5 20.7 9.1 9.9 26.4 3.8 7.8 4.6 23.2 7.2 8.4 6.0 8.0 0.8 0.0 9.0 2.6 2.1 4.1 4.2 1.1 3.7 10.8 2.7 1.2 13.7 1.4 6.0 0.7 7.0 13.2 5.6 6.4 4.1 6.2 8.7 2.9 0.6 0.2 4.8 2.1 2.2 11.9 3.8 10.2 5.3 8.6 1.2 6.6 16.1 9.8 5.1 3.3 4.9 10.9 13.7 3.7 4.3 1.1 20.3 11.9 6.0 2.7 4.8 9.2 1.2 5.8 1.3 1.4 10.0 0.9 4.7 14.6 34.5 4.3 3.0 2.0 1.6 1.2 0.2 0.2 0.5 0.0 0.5 0.7 0.5 0.5 0.2 0.6 0.3 0.7 1.1 2.0 0.1 0.1 0.6 0.0 18.5 20.3 26.9 23.5 17.0 19.9 19.2 19.3 19.6 19.4 20.7 23.2 14.2 6.4 11.2 32.0 17.9 7.0 14.7 2.7 2.8 54.1 21.1 17.3 51.7 20.0 2.6 14.7 45.9 8.8 13.1 5.4 13.7 13.4 1339.6 18.4 5.4 12.6 13.1 14.3 19.7 6.6 2.9 8.6 5.1 13.6 2.5 28.9 10.0 21.3 4.1 121.1 32.6 10.8 4.1 4.4 6.2 481.5 26.4 7.7 10.6 27.2 2.3 51.1 8.2 36.2 42.0 4.9 7.4 21.4 15.0 17.5 9.0 14.3 5.4 85.2 26.3 32.0 11.0 642.9 79.4 4.2 4.5 2.9 13.7 15.4 12.2 8.9 GKN1 "AMP18, BRICD1, CA11" ENSG00000169605 "Gastrokine 1" Q9NS71 2 68974573-68980980 "Plasma proteins, Predicted secreted proteins" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1840 "stomach 1: 37425.0" "Cell type enriched" "Detected in some" 28 "Gastric mucus-secreting cells: 9780.9" "Cancer enriched" "Detected in some" 116 "stomach cancer: 255.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 6.5;HMC-1: 17.2;MOLT-4: 12.4;NTERA-2: 16.0;REH: 7.2;U-2 OS: 10.1;U-266/70: 10.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA047684 Enhanced "Secreted to digestive system" NA NA 18000000 "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA047684: AB_2680120" "unprognostic (5.40e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.54e-1)" "prognostic favorable (4.53e-4)" 3.0 1.8 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.4 0.0 1.4 0.0 0.3 0.0 3.6 0.4 0.0 1.0 0.0 0.0 1.8 0.8 3.5 0.0 0.0 0.0 0.4 4.8 0.0 0.3 20.3 0.0 0.7 0.3 0.0 0.4 0.1 1.0 0.5 0.4 0.0 0.0 10.4 37425.0 0.4 0.0 1.1 0.2 0.2 0.1 1.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 6.5 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.4 0.0 16.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 10.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.3 3.3 9780.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.5 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.5 0.0 0.0 GKN2 "blottin, BRICD1B, GDDR, PRO813, TFIZ1, VLTI465" ENSG00000183607 "Gastrokine 2" Q86XP6 2 68945232-68952893 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "stomach 1: 4612.5" "Cell type enriched" "Detected in some" 22 "Gastric mucus-secreting cells: 2770.2" "Cancer enriched" "Detected in some" 8 "stomach cancer: 43.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.1;HaCaT: 1.1;HMC-1: 2.0;MOLT-4: 1.6;NTERA-2: 2.3;PC-3: 4.5;U-2 OS: 1.6;U-266/70: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA057765 Enhanced "Secreted to digestive system" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA057765: AB_2683520" "unprognostic (1.81e-1)" "unprognostic (1.44e-4)" "unprognostic (2.22e-1)" 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.4 0.9 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.2 0.1 80.8 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 1.4 4612.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 2.3 0.0 4.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.2 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 115.4 109.3 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.9 2770.2 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 121.2 0.0 0.0 10.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 GLA GALA ENSG00000102393 "Galactosidase alpha" P06280 X 101393273-101408012 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 229.9;Plasma cells: 171.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 328.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000237, HPA000966" Enhanced "Intracellular and membrane" NA NA 1300000 "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "HPA000237: AB_1078968, HPA000966: AB_1078969" "unprognostic (7.27e-3)" "unprognostic (1.47e-2)" "unprognostic (1.57e-2)" "unprognostic (2.94e-1)" "unprognostic (1.60e-1)" "unprognostic (3.15e-2)" "prognostic unfavorable (5.62e-5)" "unprognostic (2.53e-1)" "unprognostic (3.42e-1)" "unprognostic (1.89e-1)" "unprognostic (2.97e-2)" "unprognostic (3.27e-2)" "unprognostic (2.73e-2)" "prognostic favorable (6.16e-4)" "unprognostic (1.13e-1)" "unprognostic (5.44e-2)" "unprognostic (2.21e-1)" 15.6 21.5 5.2 12.7 5.4 25.1 26.7 6.6 6.9 13.8 6.2 13.0 22.4 10.9 17.5 9.3 15.2 11.8 9.9 5.6 6.2 15.6 12.7 17.2 13.2 7.0 7.3 9.2 6.7 31.7 9.9 22.1 7.3 7.9 15.3 6.9 10.0 39.3 6.2 9.2 13.5 15.4 6.5 13.2 9.3 3.8 6.9 12.0 7.9 6.5 15.6 14.7 9.1 8.1 30.5 117.9 30.8 31.9 68.9 26.8 13.8 34.1 51.9 63.5 176.3 64.7 45.9 33.6 70.0 35.3 151.8 70.3 65.9 38.3 53.8 19.3 47.1 18.3 87.9 78.4 19.2 26.7 328.1 24.3 11.3 72.9 21.6 17.4 50.9 18.2 28.6 71.2 60.8 52.3 24.4 53.7 48.2 72.5 46.4 18.2 39.5 81.5 95.1 61.9 11.5 19.4 78.6 34.6 30.9 54.4 15.2 51.2 29.9 20.7 23.8 52.6 27.0 23.0 26.3 25.4 36.9 39.9 23.1 22.5 37.3 11.9 6.9 38.5 9.0 8.8 5.6 8.8 29.8 9.0 5.6 6.9 21.6 5.6 40.6 10.9 7.3 20.4 5.2 5.4 6.6 6.9 5.6 6.2 7.0 7.3 7.3 6.5 6.9 8.1 31.5 16.0 10.2 3.3 65.8 30.2 32.6 23.7 45.5 4.0 34.0 23.2 7.7 4.3 19.3 11.0 6.2 38.4 25.5 26.5 17.6 22.5 3.9 57.6 19.5 30.8 33.9 12.6 3.2 18.7 26.3 66.1 39.8 97.6 31.0 9.6 8.9 7.1 93.0 8.4 3.9 15.9 20.3 28.5 229.9 0.9 11.1 115.7 88.9 4.7 30.3 17.5 14.4 3.0 3.9 14.4 25.3 18.0 171.4 20.5 30.9 9.5 29.9 5.3 6.6 22.6 70.8 6.4 5.8 31.0 23.7 75.5 33.2 19.8 19.2 27.9 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996609-33097202 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 857.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 22.0 36.1 12.1 27.8 13.0 21.9 20.5 12.5 14.8 33.4 16.0 43.5 43.0 21.9 103.6 15.4 28.2 32.0 15.5 12.5 14.8 46.0 48.2 42.7 25.8 14.3 12.9 21.4 30.8 59.4 18.5 53.8 15.4 23.2 45.6 14.9 25.3 29.3 7.7 15.8 31.0 30.6 12.4 24.4 35.5 13.5 13.5 17.5 52.8 10.8 23.0 31.8 16.2 15.1 37.4 63.6 39.8 48.3 241.9 123.7 857.2 59.1 157.6 73.7 95.1 91.3 86.5 17.9 50.9 120.9 53.9 35.1 38.1 75.5 53.7 104.9 33.0 69.9 35.3 47.4 124.3 50.5 69.9 144.9 70.2 67.0 39.2 144.1 116.5 24.7 64.3 67.0 81.8 44.6 29.6 31.6 26.4 78.0 27.0 24.7 26.4 86.6 78.4 54.4 12.0 40.3 75.0 120.2 74.4 69.3 80.3 130.2 67.7 46.8 32.2 65.2 50.1 53.2 87.9 5.9 99.6 71.2 36.7 43.9 146.2 86.4 29.2 125.8 40.4 37.9 34.3 31.8 166.5 35.6 17.9 21.8 56.6 26.0 92.1 35.1 77.1 91.9 12.1 13.0 12.5 14.8 12.5 14.8 14.3 12.9 15.4 12.4 13.5 15.1 8.7 19.2 25.3 39.2 18.6 6.0 13.6 60.1 10.8 11.3 11.5 7.5 9.1 34.3 43.3 27.6 6.2 100.1 14.1 41.9 27.4 53.5 24.8 18.7 16.0 17.4 16.9 20.6 46.7 35.4 55.3 29.2 26.0 27.1 26.6 20.6 19.6 39.7 79.5 5.0 46.0 23.5 40.7 43.9 13.9 5.0 15.2 41.7 14.2 23.4 64.6 16.5 10.3 27.2 24.2 28.1 43.4 21.1 19.8 9.9 36.2 33.1 31.0 16.2 13.1 12.9 16.3 1.0 6.6 10.1 3.4 49.1 18.7 51.0 32.0 12.1 GLB1L MGC10771 ENSG00000163521 "Galactosidase beta 1 like" Q6UWU2 2 219236598-219245478 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 52.3" "Cell type enhanced" "Detected in many" "Early spermatids: 41.5;Spermatocytes: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 19.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043058 Enhanced "Secreted - unknown location" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA043058: AB_10806375" "unprognostic (4.30e-2)" "unprognostic (6.93e-2)" "unprognostic (2.68e-2)" "unprognostic (2.08e-3)" "unprognostic (4.35e-2)" "unprognostic (1.51e-1)" "unprognostic (1.67e-3)" "unprognostic (3.32e-2)" "unprognostic (4.77e-1)" "unprognostic (2.39e-1)" "unprognostic (8.48e-3)" "unprognostic (3.27e-1)" "unprognostic (3.62e-1)" "unprognostic (1.28e-1)" "unprognostic (9.23e-3)" "unprognostic (1.33e-1)" "unprognostic (8.50e-2)" 4.6 4.8 3.1 4.0 3.4 4.5 5.3 3.3 3.0 5.3 14.7 3.1 3.1 5.9 11.4 2.5 23.1 9.0 2.2 3.0 3.7 13.6 3.1 5.3 3.0 5.5 7.0 7.1 3.1 14.4 6.8 8.5 4.5 5.6 3.7 8.0 4.5 4.8 0.9 4.6 4.1 5.8 4.4 4.9 2.8 52.3 3.7 3.4 8.4 1.0 3.4 5.9 2.1 5.6 2.8 4.8 7.4 5.9 8.0 9.8 3.7 4.6 9.7 5.7 5.3 1.9 7.7 0.9 4.1 4.1 4.3 1.5 1.9 4.6 4.5 2.6 3.6 2.9 6.9 4.5 19.7 1.1 4.4 11.4 2.9 5.4 3.3 13.5 5.3 4.3 1.8 5.3 5.4 4.0 2.5 2.7 1.3 1.0 1.3 2.5 4.1 4.0 11.5 1.6 4.7 4.2 3.9 5.3 4.3 4.9 8.4 2.6 4.1 4.7 5.8 2.8 2.6 5.0 1.7 1.5 8.8 1.2 12.3 1.9 5.1 0.3 0.7 6.4 0.4 0.4 0.5 0.7 2.1 1.0 1.1 0.7 2.1 1.0 5.4 0.9 0.2 1.7 3.1 3.4 3.3 3.0 3.0 3.7 5.5 7.0 4.5 4.4 3.7 5.6 3.2 3.2 5.1 3.3 1.3 1.8 2.6 3.6 0.6 4.7 4.9 5.6 1.9 1.5 6.3 3.7 12.5 3.4 1.9 1.1 3.9 3.8 41.5 15.7 3.9 4.2 4.9 1.3 0.9 1.8 2.2 8.4 1.1 2.2 0.0 2.7 8.6 1.3 14.5 3.3 1.1 3.2 2.0 5.6 2.4 25.6 10.8 4.4 8.8 1.9 2.7 5.0 3.1 1.0 0.5 2.1 3.3 6.4 1.8 2.7 6.5 16.5 23.9 10.2 6.6 3.8 2.2 117.4 9.7 1.8 1.7 1.4 2.0 7.0 2.4 1.7 GLB1L2 ENSG00000149328 "Galactosidase beta 1 like 2" Q8IW92 11 134331874-134378341 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 160.6" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 182.0" "Cancer enhanced" "Detected in many" "prostate cancer: 21.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;NK-cell: 3.1" "Group enriched" "Detected in many" 24 "NK-cells: 3.1;T-cells: 3.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 49.9;HaCaT: 52.6;OE19: 123.6;SCLC-21H: 34.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054808, HPA059955" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Vesicles "HPA054808: AB_2682608, HPA059955: AB_2684178" "unprognostic (2.63e-2)" "unprognostic (9.77e-3)" "unprognostic (2.32e-2)" "unprognostic (2.20e-2)" "unprognostic (8.07e-2)" "unprognostic (1.54e-1)" "unprognostic (5.98e-2)" "unprognostic (2.08e-2)" "unprognostic (1.51e-1)" "unprognostic (8.31e-2)" "unprognostic (1.67e-1)" "unprognostic (1.48e-1)" "unprognostic (4.73e-2)" "unprognostic (1.22e-2)" "unprognostic (2.64e-1)" "unprognostic (3.88e-3)" "unprognostic (1.01e-1)" 1.5 2.1 3.0 2.6 2.1 0.3 7.0 0.1 7.7 5.9 14.7 27.6 5.7 33.9 2.1 3.5 25.6 2.8 1.2 8.5 0.3 20.7 0.6 3.6 0.6 1.0 0.8 13.7 10.6 25.0 14.1 1.5 1.0 34.5 11.7 160.6 9.1 25.2 1.0 9.4 4.0 4.4 0.1 0.6 9.0 8.3 0.7 0.5 22.7 0.2 0.6 6.7 5.0 1.3 16.0 1.6 8.2 4.7 0.0 0.0 5.5 0.0 0.0 0.0 0.0 13.3 49.9 0.0 16.3 0.0 6.8 52.6 25.2 0.4 0.0 0.0 23.9 0.0 6.7 0.6 2.2 0.0 28.4 0.3 0.7 0.0 0.0 0.0 0.1 7.6 26.3 0.0 0.0 15.3 4.4 3.0 4.7 123.6 18.2 0.0 0.0 1.5 14.1 11.0 34.9 13.1 11.4 14.2 0.0 1.2 18.4 0.2 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 4.1 0.0 3.1 0.0 0.0 0.0 3.2 0.0 1.2 0.0 0.6 1.2 0.0 0.1 0.9 1.4 0.0 3.1 0.0 0.0 0.0 0.5 3.0 2.1 0.1 7.7 8.5 0.3 1.0 0.8 1.0 0.1 0.7 1.3 0.2 0.0 1.8 0.3 0.4 2.2 5.2 1.0 1.8 6.2 7.2 7.9 1.6 1.5 2.5 0.0 41.7 0.2 3.4 19.5 0.0 2.5 2.1 7.9 22.1 1.2 9.0 0.0 1.6 2.4 1.0 3.6 4.1 2.2 0.0 41.9 0.0 0.2 0.2 5.0 1.2 5.9 0.0 0.0 0.3 6.8 1.2 0.3 5.4 1.0 0.0 10.8 1.0 1.0 0.3 2.2 6.3 0.7 2.2 8.1 3.0 8.4 10.1 182.0 0.0 3.7 2.3 2.6 4.6 1.9 0.9 0.1 2.5 3.4 11.5 2.7 GLB1L3 FLJ90231 ENSG00000166105 "Galactosidase beta 1 like 3" Q8NCI6 11 134274245-134319564 "Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0;prostate: 7.9;seminal vesicle: 4.3" "Cell type enhanced" "Detected in some" "Early spermatids: 9.8;Excitatory neurons: 39.5;Inhibitory neurons: 20.9;Oligodendrocyte precursor cells: 11.6;Spermatogonia: 7.5" "Cancer enhanced" "Detected in some" "prostate cancer: 5.0" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 11 "gdT-cell: 1.2;memory CD4 T-cell: 3.1;memory CD8 T-cell: 1.9;naive CD4 T-cell: 2.4;naive CD8 T-cell: 1.9;T-reg: 1.5" "Lineage enriched" "Detected in single" 31 "T-cells: 3.1" "Cell line enhanced" "Detected in some" "HEK 293: 5.5;JURKAT: 11.4;NTERA-2: 3.4;PC-3: 4.5;SCLC-21H: 6.8" "Not detected" "Not detected" HPA039916 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA039916: AB_2676746" "unprognostic (1.64e-3)" "unprognostic (7.80e-3)" "unprognostic (5.12e-2)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (1.55e-2)" "unprognostic (8.69e-3)" "prognostic favorable (1.97e-4)" "unprognostic (6.58e-3)" "unprognostic (3.81e-1)" "unprognostic (6.95e-3)" "unprognostic (9.73e-2)" "unprognostic (1.52e-5)" "unprognostic (1.39e-1)" "unprognostic (6.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.07e-1)" 0.0 1.0 0.9 0.4 1.0 0.1 0.3 2.3 4.0 0.4 0.0 0.9 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.4 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.2 7.9 0.0 1.6 2.7 4.3 0.0 3.3 0.1 0.0 0.0 0.1 0.0 1.3 0.2 0.1 1.3 0.0 0.1 0.1 0.8 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.2 0.0 2.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 2.2 0.0 3.4 0.0 4.5 0.0 0.0 0.0 0.0 0.0 6.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 3.1 1.9 0.0 0.0 2.4 1.9 0.0 0.0 0.0 0.0 1.5 0.6 0.9 1.0 2.3 4.0 0.4 0.1 0.5 0.0 0.2 0.0 0.2 0.8 0.0 0.0 0.0 1.3 0.1 0.5 0.1 1.3 0.0 0.5 0.4 1.3 0.7 0.0 0.1 0.0 0.0 1.3 0.3 0.0 0.0 0.0 9.8 0.1 0.3 0.3 0.0 0.0 39.5 0.0 3.4 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.4 0.0 20.9 0.0 0.0 0.0 0.0 1.2 0.6 0.1 0.0 1.9 0.0 0.3 0.0 11.6 0.9 0.1 0.0 0.0 0.3 0.4 0.0 0.5 0.0 0.7 0.0 0.0 0.1 4.3 7.5 0.0 0.1 1.2 0.3 0.0 0.0 0.1 GLCE "HSEPI, KIAA0836" ENSG00000138604 "Glucuronic acid epimerase" O94923 15 69160584-69272217 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 79.0;Microglial cells: 76.8;Oligodendrocytes: 154.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 35.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 1.9;monocytes: 2.3;T-cells: 2.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 119.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040481, HPA048216" Uncertain Approved Mitochondria "Intracellular and membrane" NA NA 240000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA040481: AB_2677004, HPA048216: AB_2680317" "unprognostic (1.30e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-3)" "unprognostic (7.77e-2)" "unprognostic (1.58e-1)" "unprognostic (5.55e-3)" "unprognostic (1.00e-1)" "unprognostic (2.84e-1)" "unprognostic (1.48e-1)" "unprognostic (2.56e-1)" "unprognostic (7.47e-2)" "unprognostic (1.41e-1)" "unprognostic (2.40e-2)" "unprognostic (1.53e-1)" "unprognostic (6.00e-2)" "unprognostic (5.23e-1)" "unprognostic (4.07e-2)" 9.1 12.2 6.7 5.6 7.8 0.9 8.9 35.8 6.2 8.2 8.4 12.8 14.2 6.4 6.9 10.0 5.5 7.5 6.3 6.0 6.7 13.3 16.8 8.4 3.5 5.7 8.5 12.7 4.7 8.7 6.4 13.4 7.2 5.8 14.2 13.2 10.9 5.8 4.1 10.4 11.5 7.0 7.5 4.4 9.1 3.9 8.8 4.9 4.1 4.9 5.1 6.6 4.6 8.0 9.6 8.5 5.6 9.7 18.6 17.6 2.0 17.6 23.2 13.3 25.2 7.1 23.6 5.8 8.5 14.4 16.8 14.0 12.1 11.4 27.1 2.2 13.4 9.7 15.0 7.2 17.9 4.2 19.0 12.1 7.8 16.6 18.6 9.7 119.4 4.3 3.9 6.0 25.4 5.9 2.6 7.4 2.7 9.7 5.9 5.8 22.6 7.3 12.3 10.1 17.9 3.7 18.0 11.0 38.1 3.8 7.9 5.8 41.8 12.7 15.7 14.3 15.8 2.5 3.7 1.3 12.9 7.0 18.8 0.0 2.1 0.0 0.3 1.6 0.5 0.2 0.8 0.4 1.8 0.2 0.5 0.7 0.0 0.2 2.3 1.9 2.0 0.9 6.7 7.8 35.8 6.2 6.0 6.7 5.7 8.5 7.2 7.5 8.8 8.0 16.9 0.0 15.4 4.9 6.2 4.8 10.1 8.3 26.2 10.3 18.8 19.4 8.1 7.2 8.8 11.0 10.4 22.7 12.1 21.3 5.9 13.0 3.9 4.0 5.4 22.6 20.4 9.4 79.0 13.8 12.7 14.0 28.1 4.9 2.5 11.8 16.4 27.2 16.4 8.4 41.5 27.1 10.2 13.3 4.4 5.1 6.2 10.7 8.8 76.8 13.7 13.1 4.1 35.7 154.9 16.9 28.2 17.7 7.1 5.3 32.4 18.3 18.2 16.6 13.1 6.6 9.4 29.8 25.9 27.9 6.5 33.0 5.9 17.1 26.4 13.3 GLDC "GCSP, NKH" ENSG00000178445 "Glycine decarboxylase" P23378 9 6532467-6645729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 173.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 31.3;Cytotrophoblasts: 79.0;Extravillous trophoblasts: 41.6;Hepatocytes: 120.5;Oligodendrocyte precursor cells: 52.3;Proximal tubular cells: 31.6;Syncytiotrophoblasts: 46.0" "Cancer enhanced" "Detected in many" "testis cancer: 41.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 235.7;CACO-2: 58.2;HMC-1: 45.6;RPTEC TERT1: 95.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002318, HPA052887" Enhanced Supported Nucleoplasm,Mitochondria NA NA 740000 "Cluster 37: B-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Nucleoplasm "HPA002318: AB_1849700, HPA052887: AB_2681980" "unprognostic (6.73e-2)" "unprognostic (1.19e-1)" "unprognostic (6.50e-2)" "prognostic unfavorable (5.24e-5)" "unprognostic (1.50e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.74e-1)" "unprognostic (2.47e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.65e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-3)" "unprognostic (1.17e-2)" 0.3 0.3 15.3 1.4 15.5 0.5 0.8 14.7 23.7 0.4 12.9 1.0 0.8 0.4 5.2 3.2 0.7 0.8 0.1 14.8 14.4 38.2 173.5 1.0 1.6 14.0 13.6 0.3 0.1 0.0 4.9 15.2 13.4 0.5 0.4 1.6 1.1 1.0 1.3 4.5 0.8 0.0 13.1 1.2 1.0 3.5 15.8 0.0 5.1 0.1 1.2 1.1 0.1 15.3 0.6 4.9 2.1 25.6 0.2 0.4 235.7 0.1 0.0 0.0 0.1 58.2 0.5 0.3 5.6 0.1 0.7 0.4 0.0 0.7 0.2 1.2 13.4 0.2 0.3 38.3 0.0 0.1 45.6 0.0 0.1 1.8 0.3 1.0 9.0 4.3 0.0 0.5 1.2 1.5 0.9 0.2 27.5 4.6 3.8 1.3 0.0 0.5 95.4 1.0 22.6 11.7 0.0 21.4 0.3 13.9 5.3 0.1 3.0 0.6 0.6 2.6 1.3 1.1 34.4 0.1 0.8 2.4 5.1 0.4 0.1 0.1 0.1 0.0 0.1 0.8 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.1 0.1 0.0 0.3 15.3 15.5 14.7 23.7 14.8 14.4 14.0 13.6 13.4 13.1 15.8 15.3 0.2 0.0 0.0 17.6 1.9 0.0 0.0 0.2 1.2 0.4 1.5 0.6 0.7 11.5 0.1 31.3 0.0 79.0 0.2 0.0 5.9 0.0 12.6 5.4 0.5 0.6 0.0 0.0 21.6 0.2 41.6 0.3 0.0 10.7 0.0 1.1 2.2 120.5 7.0 0.0 15.9 0.0 0.0 2.8 0.3 10.8 0.3 0.4 0.0 1.9 0.0 9.6 0.0 52.3 1.8 0.1 0.0 0.0 15.1 0.0 0.0 31.6 0.0 0.4 0.0 1.7 0.8 4.5 5.1 0.4 0.0 46.0 0.8 0.0 0.0 0.1 GLG1 "CFR-1, ESL-1, MG-160" ENSG00000090863 "Golgi glycoprotein 1" Q92896 16 74447427-74607144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010815 Supported Supported "Golgi apparatus" NA NA 2100000 "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "HPA010815: AB_2232486" "unprognostic (3.70e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (7.42e-2)" "unprognostic (3.30e-2)" "unprognostic (1.90e-1)" "unprognostic (5.02e-3)" "unprognostic (5.13e-3)" "unprognostic (9.45e-3)" "unprognostic (8.46e-2)" "unprognostic (1.61e-1)" "unprognostic (1.29e-1)" "unprognostic (8.85e-2)" "prognostic favorable (1.56e-7)" "unprognostic (3.54e-2)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-4)" 42.7 36.8 25.0 17.4 26.3 9.0 40.3 24.0 25.7 53.3 17.3 44.5 17.3 57.8 22.4 30.9 46.7 20.4 50.5 24.7 27.5 42.6 25.6 38.2 16.3 27.0 29.0 69.0 58.1 34.3 38.9 24.9 25.2 37.5 18.7 20.3 36.1 24.9 53.8 35.2 36.4 29.9 25.0 35.1 36.3 40.6 29.5 20.0 43.1 16.4 18.9 42.3 40.8 30.0 38.4 52.2 44.7 43.3 113.7 113.2 42.8 45.0 64.2 48.6 68.3 34.4 116.0 22.8 59.8 102.9 35.8 71.1 30.1 62.1 80.1 10.3 26.1 17.9 37.8 54.3 70.5 29.3 12.6 68.0 32.8 63.6 66.3 91.3 100.8 54.8 19.0 24.9 44.2 70.0 14.1 26.0 34.7 81.2 20.6 33.9 32.6 59.5 31.6 17.1 15.8 23.3 87.3 24.9 25.0 47.7 28.2 36.5 79.1 46.1 40.9 48.2 30.3 47.4 51.2 41.1 86.3 22.5 46.6 3.2 16.7 13.3 19.1 15.7 19.2 11.6 23.8 20.9 18.5 10.1 28.2 22.6 7.3 15.4 19.9 18.4 21.0 19.0 25.0 26.3 24.0 25.7 24.7 27.5 27.0 29.0 25.2 25.0 29.5 30.0 52.8 64.1 50.7 114.3 46.4 27.1 27.2 33.0 55.8 68.5 35.6 35.6 79.5 77.2 39.7 51.5 146.0 78.0 75.6 33.5 7.9 39.9 39.7 49.2 79.3 62.0 38.6 25.0 133.4 42.5 43.6 101.4 38.7 58.0 3.8 91.0 75.3 40.7 50.1 70.7 155.3 31.9 24.4 68.8 42.1 28.1 96.9 44.4 42.7 62.8 64.8 59.6 111.2 97.5 137.3 40.8 28.8 114.3 100.2 33.6 47.8 44.2 44.3 57.9 92.1 84.6 59.9 89.2 87.9 30.5 21.6 75.2 72.4 72.4 32.9 26.4 GLI2 "HPE9, THP1, THP2" ENSG00000074047 "GLI family zinc finger 2" P10070 2 120735623-120992653 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 10.9" "Cell type enhanced" "Detected in some" "Astrocytes: 39.5;Fibroblasts: 10.4;Leydig cells: 25.1;Peritubular cells: 30.9;Skeletal myocytes: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 20.1;hTEC/SVTERT24-B: 13.1;U-2 OS: 17.9;WM-115: 18.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB008558, HPA074275" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "CAB008558: AB_2111910, HPA074275: AB_2686677" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (9.83e-3)" "unprognostic (4.63e-2)" "unprognostic (2.04e-1)" "unprognostic (9.43e-2)" "unprognostic (1.65e-2)" "unprognostic (2.19e-3)" "unprognostic (2.58e-1)" "unprognostic (9.23e-3)" "unprognostic (1.81e-2)" "unprognostic (4.49e-10)" "unprognostic (1.13e-1)" "unprognostic (8.88e-2)" "unprognostic (2.32e-2)" "unprognostic (1.42e-3)" 1.6 1.0 1.9 0.9 2.2 0.0 1.4 1.4 1.3 4.3 0.6 3.4 0.4 4.7 1.2 0.8 2.8 2.1 2.3 1.1 1.9 1.4 0.4 2.0 0.3 2.1 2.1 10.9 0.3 0.1 1.8 0.8 1.8 2.9 0.6 0.0 1.4 1.1 0.9 2.7 1.6 1.9 1.6 0.8 1.6 2.4 1.8 1.3 1.0 0.4 0.3 3.1 2.4 0.9 0.0 10.3 20.1 5.5 3.2 4.0 0.0 5.8 1.8 2.4 2.4 0.0 0.5 0.0 0.9 5.2 0.9 0.3 4.3 0.2 1.9 0.0 2.1 0.4 6.1 0.2 3.8 0.0 1.2 2.3 0.0 13.1 0.0 2.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 10.6 1.6 4.3 0.1 2.2 3.5 0.0 0.0 2.0 2.1 3.8 0.0 0.2 4.3 0.1 0.0 5.1 0.0 17.9 2.5 0.0 0.0 0.1 0.0 7.4 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.2 1.4 1.3 1.1 1.9 2.1 2.1 1.8 1.6 1.8 0.9 0.3 0.0 0.0 39.5 0.0 2.0 0.1 0.5 0.6 0.0 0.1 0.9 1.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.1 0.3 6.1 0.5 0.0 0.0 0.7 0.2 0.1 10.4 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 1.5 2.1 25.1 0.1 0.0 2.8 0.0 0.0 1.0 3.0 0.3 1.0 0.0 30.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 16.0 3.4 0.1 3.6 0.1 1.7 0.0 0.0 7.9 0.0 0.1 GLIPR1 "GliPR, RTVP1" ENSG00000139278 "GLI pathogenesis related 1" P48060 12 75480753-75503863 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 216.3;Extravillous trophoblasts: 384.2;Hofbauer cells: 242.4;Kupffer cells: 273.9;Langerhans cells: 393.2;Macrophages: 259.6;monocytes: 220.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 189.3;U-138 MG: 363.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011014 Approved "Intracellular and membrane" NA NA 64000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA011014: AB_1849714" "unprognostic (2.32e-3)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (3.31e-1)" "unprognostic (2.32e-3)" "unprognostic (4.09e-1)" "unprognostic (7.58e-2)" "unprognostic (3.10e-1)" "unprognostic (7.23e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.69e-9)" "unprognostic (9.06e-3)" "unprognostic (5.08e-2)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" 17.2 16.9 2.0 47.0 1.7 18.3 11.5 1.5 5.6 15.6 3.8 11.4 6.6 32.6 6.0 7.9 17.9 33.5 9.2 2.3 2.8 5.6 12.5 22.1 32.7 4.0 3.3 13.7 3.7 2.3 3.9 25.8 3.9 9.2 12.6 1.7 9.7 17.1 3.1 3.4 14.1 39.9 3.4 36.4 10.8 4.8 4.2 19.8 5.4 7.3 32.3 35.0 6.7 8.4 7.2 7.0 5.9 0.6 22.0 46.2 0.9 93.0 97.5 76.8 55.7 3.8 2.7 23.9 19.1 101.7 67.6 1.2 0.2 38.6 124.7 38.0 1.6 1.2 8.4 6.1 25.1 8.4 1.3 43.0 14.1 189.3 41.4 123.1 62.0 1.7 1.7 29.0 144.7 0.1 4.0 20.2 0.6 0.2 2.8 1.0 4.5 0.8 8.1 1.6 0.2 0.2 38.5 0.3 0.2 12.5 0.9 6.7 102.6 363.8 35.4 39.2 144.1 5.1 0.8 2.1 144.4 9.9 5.6 25.3 352.7 40.9 115.0 232.6 77.2 73.9 80.5 90.7 240.2 90.2 24.3 50.4 462.1 20.4 265.6 202.1 91.2 265.0 2.0 1.7 1.5 5.6 2.3 2.8 4.0 3.3 3.9 3.4 4.2 8.4 6.5 12.8 16.0 2.0 121.6 13.6 189.2 23.0 4.0 2.9 15.5 19.9 0.9 5.7 10.0 3.7 4.2 4.8 216.3 0.3 0.0 102.8 14.3 11.3 119.4 7.0 3.5 11.8 13.3 83.9 384.2 46.1 2.0 16.4 10.1 0.8 10.4 4.4 242.4 6.7 14.6 0.4 4.1 273.9 393.2 5.9 14.3 259.6 16.0 28.1 220.9 1.4 123.6 2.5 1.5 90.9 2.5 53.8 66.8 106.5 0.1 1.5 10.6 3.2 13.1 8.1 50.2 7.9 1.0 4.6 9.8 16.8 161.9 26.7 0.6 42.8 GLIPR1L1 MGC26856 ENSG00000173401 "GLIPR1 like 1" Q6UWM5 12 75334670-75370560 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 33.6" "Group enriched" "Detected in some" 7 "Early spermatids: 226.7;Spermatocytes: 179.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "NTERA-2: 109.1" "Low region specificity" "Detected in many" HPA042095 Enhanced "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA042095: AB_10796898" "unprognostic (2.45e-3)" "unprognostic (1.56e-1)" "unprognostic (4.40e-2)" "unprognostic (1.72e-1)" "unprognostic (7.47e-2)" "unprognostic (3.04e-1)" "unprognostic (2.70e-1)" "unprognostic (4.79e-2)" "unprognostic (3.01e-1)" "unprognostic (2.89e-1)" "unprognostic (7.90e-3)" "unprognostic (1.08e-1)" "unprognostic (9.13e-3)" "unprognostic (1.02e-1)" "unprognostic (1.65e-1)" "unprognostic (2.00e-1)" "unprognostic (2.11e-2)" 0.2 0.8 0.6 0.1 2.0 0.3 0.1 3.9 1.0 0.2 0.5 0.1 0.2 0.5 0.0 0.8 0.2 0.8 1.3 0.5 1.9 0.6 0.1 0.4 0.4 1.8 1.6 0.6 0.2 0.0 0.5 0.0 1.7 0.3 0.0 1.1 0.6 0.0 0.5 1.1 0.3 0.0 0.9 0.4 0.3 33.6 2.2 0.0 0.3 0.0 0.0 0.2 0.1 2.0 0.5 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.9 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.2 109.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.7 0.3 0.0 0.0 0.2 14.5 0.1 0.2 0.0 0.4 0.2 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.6 2.0 3.9 1.0 0.5 1.9 1.8 1.6 1.7 0.9 2.2 2.0 0.1 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.6 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 226.7 0.1 0.3 0.5 0.0 0.0 4.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 28.3 5.3 0.3 0.0 1.9 0.0 0.3 0.0 5.0 5.1 0.0 0.0 2.6 0.0 0.0 0.0 0.3 0.0 0.3 6.6 0.2 0.2 179.3 2.2 0.1 0.0 0.0 0.2 0.2 0.0 0.0 GLIPR1L2 MGC39497 ENSG00000180481 "GLIPR1 like 2" Q4G1C9 12 75391089-75432688 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 46.8" "Group enriched" "Detected in many" 7 "Early spermatids: 254.0;Spermatocytes: 306.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "Hep G2: 4.2;SK-BR-3: 5.6;U-2 OS: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039795, HPA039866" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" Vesicles "HPA039795: AB_10805595, HPA039866: AB_10795235" "unprognostic (1.23e-1)" "unprognostic (1.87e-1)" "unprognostic (3.32e-1)" "unprognostic (2.27e-1)" "unprognostic (7.74e-2)" "unprognostic (1.33e-1)" "unprognostic (8.78e-3)" "unprognostic (2.29e-2)" "unprognostic (1.48e-1)" "unprognostic (2.82e-1)" "unprognostic (7.68e-3)" "unprognostic (1.20e-1)" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (5.91e-2)" "unprognostic (2.57e-2)" 1.0 2.7 5.1 0.8 5.2 0.3 2.4 6.5 5.9 2.1 2.5 0.9 0.6 2.3 3.7 1.0 3.1 1.0 2.3 5.5 5.0 2.0 1.5 1.2 0.7 4.0 4.3 7.1 2.6 4.1 2.6 0.9 4.4 1.5 0.4 3.0 1.0 3.0 2.3 1.9 0.8 1.1 4.0 1.6 0.7 46.8 4.7 1.3 2.4 1.6 0.4 0.9 0.9 6.3 0.2 0.4 0.2 0.4 2.9 1.6 0.5 0.4 0.3 0.1 0.2 0.1 0.3 0.2 1.0 0.3 0.7 0.1 0.0 0.1 0.3 0.6 0.2 0.1 0.6 4.2 2.1 0.4 0.0 0.5 0.9 0.4 1.5 2.5 0.1 0.1 0.2 0.5 0.8 0.1 0.4 0.3 0.1 0.9 0.1 0.1 0.0 0.2 0.0 0.3 0.7 0.3 0.5 5.6 1.7 0.2 1.7 0.1 0.8 0.6 7.6 0.9 0.3 0.7 0.7 0.2 0.2 0.2 0.5 0.7 0.0 0.1 0.3 0.0 0.1 0.3 0.3 0.5 0.1 0.3 0.5 0.9 0.6 0.3 0.1 0.7 1.0 0.2 5.1 5.2 6.5 5.9 5.5 5.0 4.0 4.3 4.4 4.0 4.7 6.3 1.5 0.0 3.1 15.0 0.3 0.9 4.6 1.7 3.4 5.6 2.9 3.0 4.0 1.5 1.8 0.0 0.0 1.7 1.5 0.1 9.8 0.6 254.0 4.9 1.4 1.5 0.0 0.4 7.4 0.0 0.2 3.0 1.1 0.5 1.3 1.4 0.0 0.2 0.6 1.7 13.3 0.1 0.0 0.3 0.3 39.0 7.5 0.7 0.0 10.3 0.0 6.7 0.0 27.2 28.1 0.1 0.0 5.7 0.1 1.2 0.1 1.4 14.1 2.0 6.6 5.6 1.9 306.8 19.4 0.3 0.4 0.4 0.6 2.1 0.3 2.1 GLIS3 "MGC33662, ZNF515" ENSG00000107249 "GLIS family zinc finger 3" Q8NEA6 9 3824127-4348392 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Congenital hypothyroidism, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.2;choroid plexus: 20.5" "Cell type enriched" "Detected in many" 7 "Astrocytes: 649.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 21.5;HSkMC: 29.5;RPTEC TERT1: 20.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056426 Approved Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA056426: AB_2683128" "unprognostic (6.24e-2)" "unprognostic (2.30e-2)" "unprognostic (1.54e-1)" "unprognostic (3.63e-3)" "unprognostic (4.10e-1)" "unprognostic (1.88e-1)" "unprognostic (1.81e-2)" "unprognostic (7.14e-2)" "unprognostic (4.66e-2)" "unprognostic (1.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.63e-1)" "unprognostic (1.91e-3)" "unprognostic (6.88e-3)" "unprognostic (8.54e-2)" "unprognostic (1.04e-1)" "unprognostic (6.35e-2)" 4.3 1.6 5.1 2.1 5.5 0.2 1.9 4.9 4.6 7.8 20.5 2.0 0.7 3.3 2.8 0.5 8.7 6.5 2.9 5.4 10.8 7.8 3.3 3.8 1.1 24.2 18.0 6.6 9.7 2.4 2.4 1.4 11.4 3.3 2.1 1.3 3.1 8.2 1.3 0.8 1.5 2.1 13.7 2.0 1.8 2.8 6.5 0.2 18.6 0.8 0.7 4.0 2.4 13.2 1.0 8.5 2.5 0.0 3.7 9.5 0.4 5.9 21.5 3.1 4.4 1.3 3.4 0.0 4.3 5.5 9.6 0.0 2.0 0.0 6.7 2.5 1.2 0.0 0.4 0.0 11.0 0.9 0.0 29.5 0.0 9.8 1.1 5.8 0.4 0.1 0.0 0.2 2.9 0.4 0.0 1.5 0.2 0.0 0.8 0.0 5.2 0.0 20.8 0.0 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0 5.5 3.4 0.9 3.2 13.3 0.0 0.0 0.0 8.1 0.0 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 5.1 5.5 4.9 4.6 5.4 10.8 24.2 18.0 11.4 13.7 6.5 13.2 8.1 9.6 24.0 649.7 1.0 1.9 9.3 17.1 0.6 1.0 4.6 1.3 1.6 75.8 34.5 69.9 0.0 3.2 0.3 3.7 0.0 51.0 5.2 79.6 17.5 11.2 43.7 0.0 18.3 22.6 3.2 21.9 4.1 82.3 1.3 1.6 6.8 8.3 2.4 0.0 54.2 1.6 12.2 0.8 4.0 2.4 13.7 3.4 3.6 86.2 2.2 15.6 0.0 26.7 4.1 49.1 3.9 11.3 0.0 16.5 2.4 16.4 35.7 0.4 0.0 34.4 19.0 1.3 7.4 0.6 1.3 4.2 1.2 8.8 6.6 6.1 GLMP "C1orf85, MGC31963, NCU-G1" ENSG00000198715 "Glycosylated lysosomal membrane protein" Q8WWB7 1 156290089-156295689 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029121 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA029121: AB_10600794" "unprognostic (2.46e-2)" "unprognostic (1.19e-2)" "unprognostic (5.68e-2)" "unprognostic (4.22e-3)" "unprognostic (3.71e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.35e-5)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (9.21e-3)" "unprognostic (1.33e-1)" "unprognostic (7.66e-3)" "unprognostic (7.68e-3)" "unprognostic (3.90e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" 33.9 68.3 11.8 17.1 12.8 19.4 25.6 12.9 15.4 38.1 21.1 24.6 30.3 24.4 23.2 29.8 21.1 44.7 18.1 11.7 13.9 52.2 59.8 28.9 22.6 13.6 13.6 22.0 27.0 29.4 19.7 48.0 15.0 57.3 21.1 2.7 35.2 20.4 7.4 29.2 26.9 24.5 12.4 32.3 28.8 6.4 16.0 12.2 23.6 9.6 15.4 36.0 26.8 14.4 22.7 40.8 3.9 27.0 224.8 121.7 27.5 40.8 172.0 58.1 79.0 50.9 68.7 0.0 83.2 59.0 1.9 14.6 0.6 30.0 18.4 4.6 41.8 7.0 22.9 60.6 101.4 19.7 58.1 119.9 36.0 55.9 17.9 85.1 89.0 17.6 32.8 3.1 34.6 28.5 10.1 0.1 46.5 56.9 20.9 17.4 0.0 74.3 53.7 24.5 12.9 42.2 27.1 76.4 120.6 45.6 38.3 54.2 45.7 25.7 5.0 46.2 26.9 24.9 45.9 11.3 44.0 15.7 36.3 35.0 71.3 12.2 23.4 74.5 21.7 13.1 23.0 20.5 31.8 7.7 22.7 21.7 19.4 18.0 55.6 21.3 43.4 36.9 11.8 12.8 12.9 15.4 11.7 13.9 13.6 13.6 15.0 12.4 16.0 14.4 11.7 3.2 19.1 3.3 7.3 0.0 16.4 0.0 10.8 2.0 12.3 11.6 5.8 31.5 5.0 31.3 0.0 70.3 7.6 13.8 27.4 51.3 0.6 8.5 19.1 17.5 10.9 18.5 1.6 38.3 68.5 33.4 18.8 14.2 8.8 14.9 42.8 69.8 197.7 1.7 1.9 19.4 0.0 66.8 0.0 1.4 16.4 41.1 0.0 1.0 29.8 21.0 13.4 2.0 3.9 29.8 22.2 13.9 23.0 28.9 44.9 67.3 5.8 1.5 13.1 11.9 17.1 0.9 1.9 17.8 0.0 69.6 9.3 17.6 11.8 18.7 GLRB ENSG00000109738 "Glycine receptor beta" P48167 4 157076125-157172090 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.5;parathyroid gland: 33.0" "Group enriched" "Detected in many" 4 "Excitatory neurons: 168.6;Inhibitory neurons: 110.7;Oligodendrocyte precursor cells: 110.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 28.6;hTERT-RPE1: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052363 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA052363: AB_2681800" "unprognostic (7.36e-2)" "unprognostic (6.53e-2)" "unprognostic (1.44e-1)" "unprognostic (2.59e-3)" "unprognostic (5.65e-2)" "unprognostic (1.18e-1)" "unprognostic (9.47e-2)" "unprognostic (1.52e-1)" "unprognostic (1.19e-2)" "unprognostic (2.99e-2)" "unprognostic (6.81e-2)" "unprognostic (1.48e-1)" "prognostic favorable (4.89e-4)" "unprognostic (4.32e-3)" "unprognostic (1.85e-1)" "unprognostic (5.61e-2)" "unprognostic (1.66e-2)" 4.7 7.0 16.5 1.1 17.7 0.2 10.6 7.4 35.5 9.0 4.5 3.3 0.6 2.9 5.2 1.0 7.3 3.2 11.1 18.0 12.9 3.8 1.2 3.1 0.3 9.4 6.9 1.2 15.2 33.0 7.5 2.6 10.8 6.2 0.9 8.5 19.5 4.7 3.3 1.8 1.4 3.7 5.7 0.0 2.9 1.6 9.8 1.1 1.0 4.9 0.2 1.4 1.5 13.5 8.0 3.4 9.5 28.6 18.0 7.2 0.0 16.0 10.1 7.6 14.4 0.0 24.0 0.0 3.7 16.2 9.4 0.0 7.2 2.5 14.3 0.0 9.7 5.0 3.8 0.3 8.1 6.2 0.0 6.4 2.2 13.4 1.9 37.8 6.9 5.1 0.0 0.0 14.1 0.0 0.8 0.0 0.6 0.0 2.3 0.0 13.0 0.0 20.6 1.5 10.3 6.1 0.0 7.3 1.2 1.4 6.8 1.6 10.5 4.5 13.2 7.6 15.3 0.0 0.0 0.0 10.7 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 16.5 17.7 7.4 35.5 18.0 12.9 9.4 6.9 10.8 5.7 9.8 13.5 0.5 0.0 1.1 26.1 0.0 1.1 0.9 3.1 1.2 10.8 7.8 4.8 13.9 4.3 3.5 0.0 2.1 0.4 0.4 0.1 0.0 8.8 0.3 6.9 3.4 2.1 0.0 1.7 168.6 1.8 0.0 3.9 0.0 2.0 1.3 7.0 3.3 0.0 0.1 1.7 110.7 0.0 4.1 0.3 1.9 0.3 0.3 0.1 3.6 15.9 0.6 13.2 0.0 110.1 31.5 1.5 0.0 3.4 0.0 0.6 0.0 0.5 10.4 2.2 0.0 8.5 2.2 1.3 3.3 0.4 0.3 0.1 0.1 1.3 0.1 0.2 GLS "GLS1, KIAA0838" ENSG00000115419 Glutaminase O94925 2 190880821-190965552 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 316.8" "Cell type enhanced" "Detected in all" "Collecting duct cells: 391.8;Excitatory neurons: 427.1;Proximal tubular cells: 539.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 907.3;RPTEC TERT1: 419.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036223 Enhanced Supported Mitochondria "Intracellular and membrane" No No 92000 "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036223: AB_10669984" "unprognostic (7.45e-2)" "unprognostic (3.42e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (3.45e-4)" "unprognostic (1.17e-1)" "unprognostic (2.08e-3)" "unprognostic (2.51e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-1)" "unprognostic (2.40e-1)" "unprognostic (8.01e-2)" "unprognostic (9.06e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (5.03e-2)" "unprognostic (2.13e-1)" "unprognostic (4.12e-1)" 37.0 77.4 38.5 45.7 50.5 28.7 32.0 40.5 74.6 31.0 35.6 32.0 92.2 28.8 26.6 16.8 25.1 41.8 34.7 55.5 35.9 316.8 11.7 55.6 68.0 44.7 19.8 28.9 36.9 62.0 19.9 35.8 52.5 20.8 30.1 81.8 20.4 31.2 15.8 28.5 103.4 36.9 12.0 49.3 18.7 16.2 24.1 41.7 35.7 23.6 57.9 36.5 23.6 44.8 43.6 47.2 32.4 43.1 99.7 68.9 84.0 126.8 95.7 90.6 103.1 58.1 42.1 88.5 907.3 269.3 46.1 55.6 58.0 50.0 131.5 219.8 37.7 147.3 69.1 72.2 90.8 87.2 66.5 62.9 51.0 71.2 48.4 90.1 119.3 36.7 69.3 175.2 203.3 22.8 59.2 83.7 86.9 25.7 76.7 74.2 83.7 77.4 419.2 78.9 44.9 46.8 172.8 37.9 169.2 115.1 14.9 53.0 85.3 129.4 94.5 65.9 156.8 56.2 138.9 122.1 46.7 70.6 105.5 6.4 1.0 1.9 3.7 1.5 6.5 3.4 4.4 4.8 1.6 3.8 4.5 5.5 2.1 2.8 1.1 3.6 4.1 1.1 38.5 50.5 40.5 74.6 55.5 35.9 44.7 19.8 52.5 12.0 24.1 44.8 81.0 189.1 122.5 61.0 89.3 174.5 44.7 15.6 60.9 93.5 51.8 49.5 38.2 35.8 28.4 391.8 210.6 4.4 128.0 100.6 50.9 21.4 6.6 33.7 66.8 68.3 59.2 17.9 427.1 24.5 15.6 66.0 46.4 97.9 36.8 48.2 63.5 4.3 29.1 26.9 270.5 36.7 14.2 31.2 230.0 7.3 28.6 84.3 88.9 143.4 68.4 11.9 55.6 163.3 146.9 29.8 92.9 43.2 118.4 70.1 165.9 539.1 17.0 111.9 19.7 71.6 76.0 11.3 12.9 61.7 162.8 4.0 114.0 97.8 43.6 56.7 GLT6D1 GLTDC1 ENSG00000204007 "Glycosyltransferase 6 domain containing 1" Q7Z4J2 9 135623648-135639540 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "testis: 4.7" "Group enriched" "Detected in some" 39 "Early spermatids: 26.8;Late spermatids: 12.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA023424 Uncertain "Intracellular and membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA023424: AB_1849729" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 GLTPD2 ENSG00000182327 "Glycolipid transfer protein domain containing 2" A6NH11 17 4788964-4790589 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 73.8" "Group enriched" "Detected in some" 5 "Hepatocytes: 83.7;Proximal tubular cells: 135.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 25.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 3.4;CACO-2: 9.2;Hep G2: 13.7;MCF7: 4.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058295, HPA065267" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 150000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA058295: AB_2683671, HPA065267: AB_2685451" "unprognostic (4.00e-1)" "unprognostic (1.93e-1)" "unprognostic (1.95e-3)" "unprognostic (1.70e-1)" "unprognostic (3.03e-2)" "unprognostic (1.79e-4)" "unprognostic (1.40e-1)" "unprognostic (1.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.33e-2)" "unprognostic (5.62e-4)" "unprognostic (7.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.25e-1)" "unprognostic (4.79e-1)" "unprognostic (1.71e-4)" "unprognostic (7.59e-3)" 0.5 0.5 1.3 0.5 1.1 1.5 0.3 2.3 2.7 0.4 0.0 0.5 10.1 0.5 0.0 0.8 0.4 0.3 0.2 1.0 2.1 12.0 73.8 0.4 0.1 3.1 2.8 0.3 0.7 0.2 0.8 0.1 2.0 0.4 0.0 0.3 1.0 0.0 1.3 1.7 6.2 0.0 0.4 1.1 1.1 0.1 1.5 0.0 0.2 0.0 0.0 0.5 0.5 1.4 0.5 1.8 0.1 1.5 0.0 0.0 3.4 0.4 0.0 0.0 0.0 9.2 0.6 0.8 0.9 0.0 0.3 1.7 0.0 0.0 0.0 1.7 1.2 0.1 0.7 13.7 0.1 0.2 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.5 0.4 0.0 4.1 0.1 0.1 0.2 0.6 0.7 0.7 0.5 0.2 0.0 0.7 1.1 0.7 1.6 0.3 0.4 0.0 1.0 0.1 1.7 0.5 0.7 0.4 0.3 0.1 0.5 0.1 0.2 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.3 1.1 2.3 2.7 1.0 2.1 3.1 2.8 2.0 0.4 1.5 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.1 0.3 0.2 1.5 0.5 0.0 0.0 0.0 0.1 0.4 17.6 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.2 0.0 0.2 0.0 0.0 2.2 83.7 0.1 0.0 0.2 0.6 0.0 1.3 0.4 0.2 0.6 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.6 0.3 21.1 135.8 0.3 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.1 0.3 0.3 0.1 0.3 0.4 GLUD1 "GDH, GLUD" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050202-87094843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 816.4" "Cell type enhanced" "Detected in all" "Astrocytes: 294.1;Hepatocytes: 402.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 555.0" "Low region specificity" "Detected in all" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria "Intracellular and membrane" NA NA 23000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (3.55e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.81e-4)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.76e-5)" "unprognostic (1.13e-1)" "prognostic favorable (1.44e-6)" "unprognostic (2.29e-1)" "unprognostic (4.23e-2)" "unprognostic (7.19e-2)" "unprognostic (4.27e-2)" 70.1 93.0 217.2 44.8 219.0 29.2 96.4 180.4 216.8 50.2 135.8 63.4 80.9 48.1 30.0 77.0 47.4 53.3 75.6 193.3 223.2 249.2 816.4 57.7 42.9 220.9 222.9 71.6 66.2 39.0 37.1 58.8 202.3 110.5 61.5 90.2 55.6 53.2 51.1 84.2 88.6 53.3 223.2 46.4 57.0 22.3 254.6 44.8 68.1 64.4 59.2 68.1 55.6 202.3 127.1 100.3 77.1 131.5 143.0 174.5 84.0 97.7 167.8 92.4 100.5 233.0 120.6 141.5 77.8 143.4 53.0 194.7 101.4 98.5 98.0 102.7 79.8 69.0 55.9 555.0 318.1 163.2 95.5 121.3 181.5 103.2 304.9 140.3 112.0 109.3 70.7 124.0 101.0 92.1 148.1 145.7 88.2 136.9 79.8 110.4 98.3 93.1 267.4 101.8 39.7 73.9 87.8 68.8 126.1 73.9 94.3 112.8 112.4 47.8 42.5 98.2 101.0 73.6 81.4 167.5 115.3 182.8 29.3 9.1 14.2 9.7 8.3 11.1 10.3 9.8 11.2 10.1 15.9 11.3 9.9 8.0 1.2 13.6 16.0 5.9 12.6 6.5 217.2 219.0 180.4 216.8 193.3 223.2 220.9 222.9 202.3 223.2 254.6 202.3 49.3 22.4 23.9 294.1 56.6 106.0 57.5 32.2 105.3 22.5 83.3 38.2 60.2 57.2 47.3 60.7 37.5 95.7 45.6 56.1 156.5 32.5 14.2 37.3 44.0 54.1 39.4 52.6 35.8 33.8 63.8 89.0 86.2 59.7 43.2 33.6 50.7 402.3 69.1 15.2 38.0 49.5 36.7 74.1 184.5 26.0 88.0 81.4 104.9 42.2 50.6 140.0 39.1 48.7 42.9 50.2 38.3 90.7 75.7 103.4 124.2 175.5 21.6 68.9 65.7 41.3 55.9 11.4 8.6 189.5 122.3 47.6 84.6 70.9 49.6 107.3 GLUD2 GLUDP1 ENSG00000182890 "Glutamate dehydrogenase 2" P49448 X 121047610-121050094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 3.9;testis: 15.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.6;Cytotrophoblasts: 4.6;Early spermatids: 2.6;Hepatocytes: 4.6;Proximal tubular cells: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.7;K-562: 4.3;OE19: 2.1;SK-MEL-30: 5.5;THP-1: 2.7;WM-115: 6.0" "HPA042492, HPA044839, HPA061369" Uncertain Approved Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.44e-1)" "unprognostic (5.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.27e-3)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (2.42e-1)" "unprognostic (2.61e-1)" "unprognostic (2.35e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.04e-2)" "unprognostic (1.49e-2)" "unprognostic (4.77e-3)" "unprognostic (5.96e-2)" 1.7 1.7 0.0 0.1 0.3 0.0 1.2 0.0 0.8 0.4 0.5 0.5 0.0 0.4 1.7 0.5 0.4 0.4 0.9 0.4 0.0 1.6 3.9 0.5 0.1 0.0 0.0 0.4 1.0 0.5 0.4 0.8 0.0 0.4 0.0 0.1 0.6 0.2 0.5 0.6 0.4 0.1 0.0 0.1 0.6 15.4 0.1 0.0 0.4 0.1 0.1 0.4 0.4 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.8 0.0 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.1 1.2 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.8 0.0 0.0 2.3 0.1 0.0 0.5 0.0 0.6 0.0 0.4 0.1 2.6 0.0 0.0 0.0 2.1 4.6 0.1 0.1 1.9 0.2 2.6 0.6 0.8 0.9 0.0 0.0 1.2 0.4 0.5 0.8 0.0 0.5 0.0 0.1 0.0 4.6 0.5 0.0 0.4 0.1 0.0 1.2 0.3 2.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.2 3.3 0.0 0.1 0.0 0.9 0.4 1.2 1.0 0.1 0.1 2.5 0.3 0.7 0.2 0.3 GM2A SAP-3 ENSG00000196743 "GM2 ganglioside activator" P17900 5 151212150-151270440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Gangliosidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 224.7;Hofbauer cells: 100.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 30.9;dendritic cells: 39.6;monocytes: 40.4" "Cell line enhanced" "Detected in all" "BEWO: 207.1;HBEC3-KT: 291.8;hTCEpi: 287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008063 Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" NA NA 19000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cytosol" "HPA008063: AB_1849842" "unprognostic (4.33e-2)" "unprognostic (8.97e-3)" "unprognostic (2.27e-1)" "unprognostic (3.01e-1)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.77e-5)" "unprognostic (1.22e-1)" "unprognostic (1.72e-2)" "unprognostic (1.31e-2)" "unprognostic (1.50e-2)" "unprognostic (5.33e-3)" "unprognostic (9.81e-2)" "unprognostic (4.24e-2)" "unprognostic (4.42e-2)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" 17.4 20.5 29.3 30.0 39.7 20.6 28.0 38.9 31.1 30.8 17.9 19.7 15.8 15.1 30.8 56.2 15.4 23.4 26.2 27.1 34.3 11.4 24.8 39.0 61.4 42.6 37.9 21.3 14.9 28.3 6.6 57.9 44.3 21.1 26.3 11.7 17.0 17.9 7.2 81.8 16.3 20.0 39.0 36.0 15.8 11.6 36.2 72.3 13.0 10.5 77.9 40.3 49.5 46.7 22.3 14.8 15.1 71.7 98.0 48.2 207.1 35.0 75.1 19.0 25.6 30.3 26.1 71.9 35.1 26.9 51.1 60.0 16.7 291.8 27.2 41.4 10.5 11.7 16.8 37.9 23.7 19.1 117.1 65.4 287.0 24.4 16.4 26.0 27.6 85.1 11.4 30.7 30.1 9.6 38.4 18.0 10.2 11.4 32.3 17.7 7.1 46.3 18.4 43.3 3.9 13.4 29.1 133.0 58.3 52.0 30.7 22.5 24.6 46.0 17.6 38.3 10.6 75.2 96.8 187.0 53.1 30.1 19.4 7.6 40.4 2.4 3.7 13.6 2.7 30.9 4.3 3.9 39.6 29.8 6.1 4.8 8.7 4.4 3.4 28.0 5.4 18.6 29.3 39.7 38.9 31.1 27.1 34.3 42.6 37.9 44.3 39.0 36.2 46.7 5.8 16.0 23.0 5.5 25.0 14.9 18.5 63.2 26.7 5.8 5.4 15.5 30.9 0.0 29.7 18.4 2.1 53.6 8.3 4.4 1.9 7.2 0.5 5.7 6.8 7.3 3.6 5.0 2.2 8.1 224.7 10.2 10.7 7.7 69.6 16.3 8.6 24.2 100.8 6.7 2.7 5.4 10.2 55.7 32.5 1.6 8.1 67.8 8.8 2.8 52.5 8.0 7.2 3.5 9.5 6.0 4.7 13.9 28.8 6.7 6.2 5.4 19.9 3.7 0.0 7.9 6.9 1.8 4.2 45.6 23.9 52.5 5.6 6.4 6.7 36.5 GML LY6DL ENSG00000104499 "Glycosylphosphatidylinositol anchored molecule like" Q99445 8 142834247-142916506 "Predicted intracellular proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 56 "adrenal gland: 194.0" "Cell type enhanced" "Detected in some" "granulocytes: 4.5;Sertoli cells: 6.6;Spermatocytes: 24.2;Spermatogonia: 7.5" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" 0.0 194.0 0.0 0.2 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 24.2 7.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 GMPPA ENSG00000144591 "GDP-mannose pyrophosphorylase A" Q96IJ6 2 219498884-219506989 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 79.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035512, HPA035513" Approved Approved Nucleoplasm NA NA 51000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA035512: AB_2674660, HPA035513: AB_10671934" "unprognostic (3.43e-1)" "unprognostic (3.95e-2)" "unprognostic (7.75e-3)" "unprognostic (1.40e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.57e-1)" "unprognostic (2.39e-1)" "unprognostic (2.25e-1)" "unprognostic (1.17e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.90e-10)" "prognostic favorable (5.24e-4)" "unprognostic (1.28e-1)" "unprognostic (2.01e-1)" "unprognostic (2.28e-1)" 22.6 25.8 19.3 23.9 20.1 19.0 21.6 20.1 22.6 32.1 22.4 29.7 28.8 26.4 68.7 25.5 24.6 19.7 27.1 20.1 20.5 25.7 68.5 20.9 20.7 20.5 19.8 20.1 60.3 24.7 48.5 21.2 20.0 37.3 32.3 8.0 40.1 23.4 22.8 17.8 30.0 26.2 19.6 35.2 32.5 9.6 21.3 13.2 28.6 12.6 23.8 25.2 23.1 19.8 43.4 36.0 21.2 37.8 79.5 70.6 56.4 73.8 98.6 85.2 105.2 66.8 40.5 23.4 51.1 107.7 54.3 40.1 39.7 63.9 73.3 45.3 35.0 45.5 35.7 119.3 72.0 24.1 51.7 54.3 50.7 79.9 89.9 43.9 52.8 29.7 82.3 66.3 66.8 55.5 23.8 45.3 21.7 52.8 38.5 18.6 22.9 42.4 48.6 30.1 27.4 24.0 31.0 46.3 52.1 44.4 31.5 38.8 30.9 49.2 33.6 89.4 40.9 45.4 19.4 28.9 100.4 26.7 55.8 76.0 52.6 37.3 30.1 56.0 35.0 32.1 23.4 31.9 43.5 24.1 17.3 15.7 11.8 36.4 59.3 43.9 34.8 35.2 19.3 20.1 20.1 22.6 20.1 20.5 20.5 19.8 20.0 19.6 21.3 19.8 12.5 16.0 14.4 5.5 18.8 5.6 12.8 25.2 6.2 6.1 20.9 13.5 13.2 10.0 20.1 16.5 6.2 37.6 16.6 37.7 35.2 24.3 1.3 8.5 15.8 9.5 10.8 19.1 3.1 30.0 79.8 19.2 38.7 14.4 19.0 13.3 11.0 36.3 33.7 1.7 3.6 61.6 10.2 17.6 10.0 3.4 18.3 16.5 12.4 1.9 15.9 11.1 12.3 1.0 4.9 19.0 37.6 13.5 50.3 15.1 45.9 36.8 11.6 4.7 13.1 7.9 27.1 4.4 6.5 9.9 8.5 47.2 13.5 10.7 29.1 15.1 GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, P84996, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 1886.1;Late spermatids: 1756.9;Skeletal myocytes: 1998.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favorable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" 784.8 1215.3 1564.4 512.6 1524.7 887.4 578.9 1413.1 1768.3 828.5 1373.3 657.1 492.4 611.4 1253.8 883.1 742.9 672.7 1990.6 1557.3 2716.9 625.0 651.1 640.3 769.2 1710.5 1949.4 766.5 1917.7 1799.4 1153.6 884.6 1963.4 577.3 607.3 731.2 2943.9 594.4 2400.4 526.8 527.3 782.4 1598.4 606.6 587.1 357.9 1882.0 854.4 3432.2 2813.1 800.0 687.1 239.3 1483.9 215.6 897.3 1501.9 663.3 2691.8 1822.3 1200.1 1219.1 1635.0 1937.3 1201.8 2480.5 1446.7 911.9 1670.3 2314.3 1305.6 976.1 1499.0 2195.3 1540.9 401.4 784.6 984.9 1651.7 2232.7 1420.7 641.6 483.0 1566.4 1113.6 875.1 1399.1 1561.0 1669.7 1100.6 692.0 1294.6 1319.1 4131.0 1759.5 1452.8 487.9 214.0 894.4 1436.7 1287.3 1589.4 2165.5 1315.8 1818.3 3853.2 2157.6 2117.1 1354.2 1921.8 1570.0 1581.7 1343.3 2210.2 1477.0 688.5 1452.3 1314.0 993.3 1583.2 900.0 473.7 1107.1 217.9 96.7 114.2 68.9 127.3 80.0 103.2 73.4 74.8 129.2 93.6 65.8 82.6 103.4 95.6 150.3 174.9 92.7 100.9 1564.4 1524.7 1413.1 1768.3 1557.3 2716.9 1710.5 1949.4 1963.4 1598.4 1882.0 1483.9 982.6 221.2 258.8 192.0 310.8 130.4 182.0 130.0 205.5 397.8 465.6 684.4 1025.3 237.4 212.2 261.1 56.3 832.6 390.8 357.3 444.1 233.9 734.9 487.7 515.7 518.3 463.1 252.1 232.5 228.9 342.0 380.9 196.3 685.0 138.6 542.3 380.1 256.4 379.1 1886.1 439.7 327.2 181.0 380.4 405.7 1756.9 265.3 437.1 222.3 236.1 204.0 1367.2 137.0 194.5 166.6 339.9 300.0 197.1 309.7 268.1 273.7 153.6 218.0 222.0 210.4 1998.0 560.4 226.0 73.6 240.5 117.8 1211.7 301.8 860.9 304.4 316.5 GNLY "D2S69E, LAG-2, LAG2, NKG5, TLA519" ENSG00000115523 Granulysin P22749 2 85685175-85698852 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 288.7;endometrium 1: 71.9;lymphoid tissue: 86.3" "Group enriched" "Detected in many" 5 "dendritic cells: 5070.6;NK-cells: 8318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 17623.2" "Group enriched" "Detected in all" 63 "NK-cells: 17623.2;T-cells: 7874.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025186, HPA058021" Enhanced "Secreted to blood" NA NA 2920000 17000 "Cluster 48: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB025186: , HPA058021: AB_2683581" "unprognostic (5.80e-2)" "unprognostic (5.64e-3)" "unprognostic (6.68e-2)" "prognostic favorable (3.48e-5)" "unprognostic (4.34e-2)" "unprognostic (9.22e-2)" "unprognostic (2.60e-1)" "unprognostic (2.79e-2)" "prognostic favorable (6.60e-5)" "unprognostic (2.61e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (8.46e-2)" "unprognostic (3.37e-1)" "unprognostic (1.86e-1)" "prognostic favorable (8.07e-4)" 6.9 2.7 8.1 11.6 7.8 288.7 5.2 8.1 18.7 4.3 7.1 5.7 4.0 71.9 3.9 2.6 6.1 6.5 4.3 7.8 9.8 2.9 10.4 36.8 21.9 12.7 11.6 1.5 1.2 0.8 1.8 17.0 10.6 2.0 6.1 0.5 2.0 5.3 9.2 1.5 10.3 4.3 8.8 86.3 5.0 0.9 9.8 3.5 3.6 3.5 17.6 6.4 2.5 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 0.1 0.0 177.1 26.2 17.7 7874.6 26.3 2145.8 34.2 837.4 3344.7 22.4 23.0 231.3 2928.7 202.5 17623.2 32.3 58.2 40.3 8118.6 8.1 7.8 8.1 18.7 7.8 9.8 12.7 11.6 10.6 8.8 9.8 9.8 26.8 12.8 78.9 0.0 23.3 7.0 0.2 0.0 0.0 0.1 7.2 3.7 3.0 10.0 6.2 0.0 2.1 2.3 5070.6 1.3 1.9 1.9 0.0 7.5 12.0 13.0 1.8 47.2 0.2 0.0 3.4 29.3 0.5 10.6 52.4 0.1 23.2 5.3 6.0 0.0 0.1 3.3 0.0 22.4 7.2 0.2 0.3 28.4 80.0 9.4 48.6 0.1 8318.3 0.0 0.1 0.0 1.2 0.0 247.4 0.1 2.4 9.5 3.6 0.2 0.0 7.0 5.4 0.2 0.6 0.6 7.7 1.1 1230.0 1.0 1.6 0.6 GNPTG "C16orf27, c316G12.3, CAB56184, GNPTAG" ENSG00000090581 "N-acetylglucosamine-1-phosphate transferase subunit gamma" Q9UJJ9 16 1351931-1364113 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 135.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004055 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 560000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" Cytosol "HPA004055: AB_1079006" "unprognostic (4.37e-2)" "unprognostic (2.20e-2)" "unprognostic (1.84e-1)" "unprognostic (9.57e-3)" "unprognostic (2.70e-3)" "unprognostic (2.09e-1)" "unprognostic (3.03e-2)" "unprognostic (3.66e-1)" "unprognostic (1.69e-1)" "unprognostic (3.29e-1)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.14e-2)" "unprognostic (2.20e-1)" "unprognostic (2.31e-1)" "unprognostic (4.85e-2)" "unprognostic (2.07e-2)" 34.8 94.0 33.5 19.3 41.3 25.0 34.5 37.8 43.3 31.4 43.2 27.9 17.7 29.7 28.9 23.6 28.5 23.7 28.7 32.6 34.8 37.1 40.9 28.4 27.9 38.8 35.5 35.7 39.6 40.2 32.9 20.9 39.3 29.9 16.2 15.6 42.9 20.7 34.6 37.2 30.9 14.9 35.1 38.3 34.8 21.4 35.7 13.3 33.9 16.9 14.4 28.8 26.5 44.5 13.3 21.2 15.3 26.9 135.2 50.3 20.1 38.3 49.6 14.9 28.4 19.1 37.0 8.4 43.0 51.8 22.5 24.0 9.2 22.4 7.6 27.0 20.2 11.3 73.9 33.0 57.6 18.2 43.2 67.3 38.4 14.2 20.3 41.6 27.5 15.2 13.7 48.4 24.6 30.7 8.7 18.7 14.4 33.9 11.8 30.5 12.9 38.6 37.3 17.1 12.0 15.5 38.5 39.2 28.7 8.5 36.9 27.3 27.0 29.8 25.5 24.6 19.1 50.6 40.4 17.7 24.4 15.6 20.3 70.5 77.0 49.5 43.3 74.4 39.6 32.1 36.7 40.8 61.5 31.1 33.4 30.8 32.0 32.6 73.9 52.2 46.9 49.7 33.5 41.3 37.8 43.3 32.6 34.8 38.8 35.5 39.3 35.1 35.7 44.5 39.7 41.7 41.7 17.3 31.9 20.9 26.5 25.4 46.7 15.1 34.0 42.9 9.4 37.1 43.2 20.2 25.0 25.0 34.9 25.8 9.8 27.4 2.6 17.7 29.8 25.6 9.1 9.9 22.7 14.5 20.3 49.7 47.4 23.7 24.6 21.1 30.7 35.2 50.2 8.4 20.5 18.0 14.2 43.4 41.7 4.6 30.1 47.8 33.8 9.4 25.7 31.0 30.9 15.1 32.4 14.8 32.9 17.7 76.1 22.1 32.1 41.7 28.5 24.5 19.7 24.4 22.9 25.4 24.2 48.1 20.3 31.1 30.6 20.5 21.7 24.5 GNRH1 "GNRH, GRH, LHRH" ENSG00000147437 "Gonadotropin releasing hormone 1" P01148 8 25419258-25424654 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 9.9;Peritubular cells: 9.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 21.1" "Group enriched" "Detected in many" 4 "basal ganglia: 19.7;hypothalamus: 12.1;olfactory bulb: 6.7" "Group enriched" "Detected in some" 23 "basal ganglia: 14.1;hypothalamus: 32.3" HPA027532 Supported "Secreted to blood" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA027532: AB_10612111" "unprognostic (6.49e-3)" "unprognostic (7.62e-2)" "unprognostic (2.90e-1)" "unprognostic (5.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.53e-4)" "unprognostic (7.80e-3)" "unprognostic (2.97e-2)" "unprognostic (1.39e-1)" "unprognostic (7.99e-2)" "unprognostic (3.45e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.08e-9)" "unprognostic (7.98e-3)" "unprognostic (5.11e-2)" "unprognostic (3.49e-1)" "unprognostic (3.68e-2)" 5.1 2.3 5.4 1.4 8.8 3.0 4.9 7.7 7.2 9.0 6.4 6.7 1.9 4.2 4.7 5.7 6.2 1.8 7.7 5.4 15.8 6.0 3.2 6.8 2.2 6.5 6.2 8.6 4.0 0.6 4.7 1.4 6.8 8.3 1.7 9.2 5.4 1.7 3.1 8.6 5.9 1.0 5.2 7.0 4.3 4.6 6.7 1.9 4.4 1.0 1.7 5.7 8.5 8.1 1.0 1.5 4.0 2.2 1.4 4.7 1.7 3.7 1.4 1.1 1.7 1.5 1.1 1.3 0.8 2.1 2.6 3.8 1.2 0.3 2.7 1.7 3.3 1.4 5.9 1.5 1.1 0.2 1.4 2.6 2.1 0.8 0.7 3.6 0.9 1.3 1.5 1.1 1.8 0.6 1.4 3.2 1.4 1.2 0.5 0.9 0.6 0.6 1.0 0.7 21.1 0.7 1.1 0.7 1.4 1.5 0.7 1.8 3.4 3.1 1.5 3.8 1.5 0.3 0.2 1.8 1.5 1.0 1.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 5.4 8.8 7.7 7.2 5.4 15.8 6.5 6.2 6.8 5.2 6.7 8.1 2.4 0.0 0.5 3.3 1.1 5.0 1.9 1.7 5.2 3.6 2.5 1.3 1.8 1.5 1.4 3.7 4.2 0.1 1.0 2.3 0.0 0.2 0.3 0.7 0.6 2.1 1.8 0.0 3.0 0.6 0.4 3.1 0.0 1.0 0.0 1.0 1.4 0.3 0.5 0.0 2.8 0.5 0.0 0.8 2.2 0.5 9.9 0.4 3.6 2.8 0.8 0.6 4.1 1.5 1.7 0.6 0.6 9.8 1.8 3.7 1.8 0.2 0.9 3.9 0.0 2.4 1.9 1.8 1.2 3.4 2.4 0.1 1.4 0.5 1.4 1.8 GNRH2 ENSG00000125787 "Gonadotropin releasing hormone 2" O43555 20 3043622-3045747 "Predicted secreted proteins" Hormone "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.8" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Early spermatids: 1.2;Excitatory neurons: 2.0;Inhibitory neurons: 2.0;Late spermatids: 1.8;Oligodendrocytes: 1.3;Sertoli cells: 6.6" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-266/84: 3.8" "Low region specificity" "Detected in many" HPA004338 Uncertain "Secreted to blood" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA004338: AB_1079012" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (1.20e-2)" "unprognostic (2.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.87e-2)" "unprognostic (1.36e-2)" "unprognostic (4.04e-3)" "unprognostic (7.00e-2)" "unprognostic (1.93e-2)" "unprognostic (2.47e-4)" "unprognostic (2.69e-1)" "unprognostic (2.98e-2)" "unprognostic (1.72e-1)" "unprognostic (3.29e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" 0.5 0.5 1.7 0.6 1.3 0.3 0.3 3.8 2.0 0.4 0.6 0.2 0.2 0.5 0.6 0.3 0.9 0.5 0.5 2.0 1.3 0.7 2.0 0.3 0.4 1.0 0.6 2.2 0.1 0.2 0.9 0.2 0.7 1.9 0.1 0.3 0.8 0.8 0.1 0.1 0.2 0.0 0.1 0.3 1.0 1.4 1.2 0.1 1.1 0.0 0.0 0.3 0.3 0.8 0.5 0.5 1.4 1.8 0.8 0.2 0.2 0.3 0.0 0.2 0.3 0.9 0.3 0.7 0.0 0.1 0.5 1.5 0.5 0.5 0.4 0.5 1.6 0.6 0.6 1.1 0.0 0.0 0.9 1.1 1.1 1.1 0.0 0.2 0.4 1.2 0.7 0.2 0.6 0.5 0.3 1.2 0.6 0.0 0.0 0.4 0.2 0.4 0.2 1.3 2.1 0.9 0.1 1.2 0.7 0.6 1.3 0.6 0.0 0.8 0.3 0.7 0.8 0.5 3.8 0.4 0.7 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.3 3.8 2.0 2.0 1.3 1.0 0.6 0.7 0.1 1.2 0.8 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.1 0.0 0.0 0.0 2.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 GNS ENSG00000135677 "Glucosamine (N-acetyl)-6-sulfatase" P15586 12 64713445-64759431 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 198.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 228.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013695, CAB026011, HPA048508" Enhanced "Intracellular and membrane" NA NA 510000 "Cluster 51: Monocytes - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "CAB026011: , HPA013695: AB_1849741, HPA048508: AB_2680423" "unprognostic (8.07e-2)" "unprognostic (2.39e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (7.76e-4)" "unprognostic (9.33e-2)" "prognostic unfavorable (1.94e-5)" "unprognostic (1.26e-1)" "unprognostic (4.03e-1)" "unprognostic (2.62e-3)" "unprognostic (3.04e-2)" "unprognostic (3.30e-2)" "unprognostic (3.28e-3)" "unprognostic (1.42e-1)" "unprognostic (3.77e-2)" "unprognostic (1.09e-1)" "unprognostic (3.04e-1)" 106.1 174.7 18.0 56.4 19.9 25.4 51.9 20.4 21.3 58.9 80.7 35.3 34.6 49.5 38.5 26.2 43.8 63.7 52.9 17.2 26.4 132.0 56.2 71.5 41.0 30.0 23.3 64.3 24.1 76.8 23.0 80.2 25.5 38.5 36.9 25.1 32.9 47.7 30.1 26.3 41.4 69.2 22.5 51.2 34.6 31.8 27.3 20.5 72.8 29.0 26.9 63.7 27.6 31.2 41.0 61.3 50.7 81.4 240.0 145.2 108.8 92.0 213.5 108.4 117.1 55.9 53.3 17.4 117.0 117.8 133.3 33.1 49.1 52.6 119.5 51.4 36.6 41.4 45.4 36.4 109.3 30.6 346.2 139.6 62.9 111.5 49.3 342.0 200.1 24.7 28.8 117.2 156.8 32.6 8.1 17.9 19.4 102.8 53.2 23.8 77.3 53.7 91.5 116.2 33.7 37.3 119.6 56.6 82.4 65.8 102.2 40.4 185.1 104.5 54.8 101.8 54.4 112.1 143.4 14.9 151.1 58.4 72.1 51.7 136.9 27.5 29.3 158.4 21.9 13.0 15.9 22.6 78.2 10.0 16.4 16.4 56.6 18.4 228.5 19.3 13.0 101.9 18.0 19.9 20.4 21.3 17.2 26.4 30.0 23.3 25.5 22.5 27.3 31.2 52.6 48.1 31.7 19.2 11.0 16.6 8.4 14.8 11.4 10.5 28.4 17.0 59.9 22.8 24.2 103.0 18.8 24.3 18.8 24.2 1.9 36.2 24.4 26.5 25.5 50.6 41.9 15.4 25.0 15.1 19.7 40.2 12.2 32.9 48.1 36.3 58.5 57.9 81.0 16.8 31.3 16.6 18.3 198.8 46.5 24.5 34.8 107.8 16.0 27.2 79.0 20.1 13.4 15.1 19.9 20.0 15.7 37.2 16.0 17.2 60.9 64.3 42.8 7.5 6.6 23.1 24.9 11.3 7.8 10.5 12.9 29.1 13.2 30.0 18.2 19.2 GOLM1 "bA379P1.3, C9orf155, FLJ23608, GOLPH2, GP73" ENSG00000135052 "Golgi membrane protein 1" Q8NBJ4 9 86026146-86100173 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 396.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 362.8;Early spermatids: 339.0;Gastric mucus-secreting cells: 245.6;Ionocytes: 325.5;Late spermatids: 391.6;Pancreatic endocrine cells: 282.9;Paneth cells: 265.2;Undifferentiated cells: 245.6" "Cancer enhanced" "Detected in all" "prostate cancer: 343.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.9;classical monocyte: 3.6;gdT-cell: 3.5;intermediate monocyte: 2.6;neutrophil: 4.2;non-classical monocyte: 4.2;plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 372.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010638, HPA011929, CAB015341" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" NA NA 81000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" "CAB015341: AB_2113334, HPA010638: AB_1849886, HPA011929: AB_1849888" "unprognostic (1.47e-1)" "unprognostic (2.31e-2)" "unprognostic (1.10e-1)" "prognostic favorable (8.14e-5)" "unprognostic (1.97e-1)" "unprognostic (4.40e-3)" "prognostic unfavorable (1.30e-4)" "unprognostic (4.89e-3)" "unprognostic (2.81e-1)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "unprognostic (1.34e-2)" "unprognostic (5.59e-3)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (2.87e-3)" "unprognostic (1.23e-1)" 22.2 159.8 72.5 33.8 78.8 6.6 39.5 69.2 84.5 70.0 99.0 195.7 235.1 40.1 15.7 13.6 38.1 131.0 12.7 72.1 93.8 74.7 19.0 14.7 9.7 73.4 76.1 36.9 41.6 37.6 36.4 17.2 69.9 143.2 163.9 25.5 173.4 10.5 9.4 14.9 61.3 28.4 80.1 41.7 396.2 17.4 108.0 45.4 68.1 4.8 5.6 38.3 14.9 79.2 146.0 139.5 102.4 116.7 129.3 74.3 108.0 64.8 46.6 99.9 80.5 69.4 282.9 2.7 62.6 126.2 96.6 109.4 63.7 64.1 71.9 5.0 101.2 45.3 89.1 3.4 76.8 67.3 34.9 113.4 34.2 94.1 34.0 124.9 172.9 21.2 28.7 4.2 57.3 68.4 8.3 49.6 161.9 188.9 99.6 42.9 116.9 21.8 166.0 61.2 115.1 72.0 88.2 189.0 73.8 66.1 106.7 68.1 110.5 25.9 72.6 79.3 78.3 372.3 37.4 0.9 112.2 29.8 57.8 1.9 3.6 0.4 3.5 2.6 0.4 0.6 0.2 0.5 0.4 0.6 0.4 0.7 4.2 0.7 4.2 1.5 0.1 1.8 72.5 78.8 69.2 84.5 72.1 93.8 73.4 76.1 69.9 80.1 108.0 79.2 13.8 9.6 15.3 30.3 1.7 2.3 10.8 11.3 4.6 20.1 41.4 21.1 4.9 80.1 80.9 35.0 8.4 8.4 10.7 362.8 25.4 168.4 339.0 78.0 49.8 20.5 73.1 11.2 47.0 222.2 35.0 30.4 245.6 56.8 1.3 65.9 8.6 11.1 11.8 67.3 43.2 95.5 325.5 5.0 2.6 391.6 18.3 6.6 23.2 6.5 6.9 16.9 12.3 82.0 19.3 282.9 265.2 13.2 3.2 72.6 71.8 16.0 78.6 6.7 0.0 13.5 19.5 10.3 38.7 2.9 1.0 6.4 5.2 60.7 245.6 29.1 GOLM2 "CASC4, DKFZp459F1927, H63" ENSG00000166734 "Golgi membrane protein 2" Q6P4E1 15 44288719-44415758 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 19.9;Cardiomyocytes: 24.0;Cytotrophoblasts: 16.3;dendritic cells: 16.1;Extravillous trophoblasts: 19.4;Fibroblasts: 18.2;Hofbauer cells: 27.3;Syncytiotrophoblasts: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043015, HPA049488" Enhanced Enhanced "Golgi apparatus" NA NA 1200000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "HPA043015: AB_2678271, HPA049488: AB_2680790" "unprognostic (2.64e-2)" "unprognostic (2.63e-1)" "unprognostic (3.38e-1)" "unprognostic (1.81e-2)" "unprognostic (8.08e-2)" "unprognostic (1.35e-1)" "unprognostic (1.20e-2)" "unprognostic (2.20e-1)" "unprognostic (2.40e-1)" "unprognostic (1.68e-2)" "unprognostic (4.99e-2)" "unprognostic (2.60e-2)" "prognostic favorable (1.45e-5)" "unprognostic (2.15e-1)" "unprognostic (3.56e-2)" "unprognostic (9.65e-2)" "unprognostic (1.12e-1)" 39.5 84.5 48.5 32.4 47.0 16.5 43.2 43.1 59.2 57.9 62.4 45.7 28.8 50.4 53.5 23.7 53.8 50.5 33.1 42.8 52.6 54.0 60.9 40.9 30.8 49.6 51.5 55.3 37.4 82.0 38.7 34.4 46.9 67.5 43.8 33.7 47.8 56.1 22.3 13.2 29.8 44.4 46.7 35.4 49.4 34.6 52.9 28.9 84.6 26.3 29.5 39.2 24.3 52.7 45.0 38.7 51.9 92.6 141.4 121.8 32.0 78.6 125.2 44.9 57.1 19.3 80.0 13.5 106.4 119.3 47.8 53.8 34.4 25.5 48.2 64.6 19.5 21.4 41.8 35.9 65.1 42.5 68.1 72.1 28.3 49.8 38.4 126.8 53.4 34.2 33.0 103.4 56.2 23.2 36.7 33.2 14.8 60.8 27.5 30.5 29.3 43.3 58.8 54.4 23.3 53.2 60.7 57.0 26.6 28.1 64.1 49.2 76.4 78.1 39.8 112.5 69.5 79.0 145.1 27.9 92.6 58.5 51.7 20.9 14.7 20.8 15.2 9.8 16.3 11.9 12.4 15.2 12.0 10.7 9.5 9.9 37.8 10.5 18.2 10.6 13.2 13.6 48.5 47.0 43.1 59.2 42.8 52.6 49.6 51.5 46.9 46.7 52.9 52.7 19.9 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 16.3 16.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 19.4 18.2 0.0 0.0 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 12.7 2.9 0.0 0.0 0.0 GOT2 "KAT4, KATIV, KYAT4, mitAAT" ENSG00000125166 "Glutamic-oxaloacetic transaminase 2" P00505 16 58707131-58734342 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Aminotransferase, Transferase" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 698.4;tongue: 726.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 341.9;Hepatocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018139, HPA058537" Enhanced "Intracellular and membrane" NA NA 2800000 "Cluster 13: T-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA018139: AB_1849903, HPA058537: " "unprognostic (1.50e-2)" "unprognostic (4.79e-2)" "unprognostic (2.73e-3)" "unprognostic (2.63e-3)" "unprognostic (3.02e-2)" "prognostic unfavorable (1.61e-4)" "prognostic favorable (5.75e-5)" "unprognostic (1.12e-2)" "unprognostic (3.19e-1)" "unprognostic (3.72e-2)" "unprognostic (2.27e-1)" "unprognostic (3.00e-1)" "prognostic favorable (2.90e-9)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (2.22e-1)" 19.6 73.9 52.4 27.4 55.9 21.1 36.3 62.5 66.9 34.1 129.4 57.6 37.4 36.5 66.3 66.9 46.7 24.1 313.2 57.9 59.3 88.0 321.4 25.2 35.6 60.6 51.0 29.4 33.2 98.6 46.7 24.7 62.5 59.0 65.0 91.4 47.7 65.7 698.4 41.1 35.7 46.7 50.1 28.5 54.9 28.9 58.7 35.9 42.6 726.8 57.0 57.0 45.1 61.0 137.2 182.4 93.8 114.8 66.6 59.8 122.0 101.4 108.8 197.6 107.7 158.9 120.1 302.3 117.3 114.6 86.5 195.5 203.2 199.2 250.1 83.1 182.0 81.4 92.1 179.3 84.2 132.3 71.9 58.4 110.9 125.2 108.2 112.4 201.8 141.9 167.0 30.6 102.2 122.5 164.0 128.0 127.7 90.8 338.0 177.8 142.7 291.1 187.9 197.7 148.2 107.6 195.2 208.5 74.8 84.2 105.5 42.7 82.3 71.4 129.3 56.2 132.4 69.9 68.6 247.4 76.7 130.9 73.8 4.6 20.6 7.4 28.3 16.9 43.7 26.5 33.1 34.1 34.7 22.3 30.1 28.4 1.8 30.2 18.4 30.0 48.7 31.2 52.4 55.9 62.5 66.9 57.9 59.3 60.6 51.0 62.5 50.1 58.7 61.0 15.1 9.6 15.8 11.8 19.8 32.0 37.0 39.4 34.1 34.5 27.5 16.3 341.9 22.8 22.5 36.8 77.2 42.6 11.8 42.6 56.7 50.8 4.0 30.4 20.0 23.8 20.5 39.3 24.7 42.5 38.8 21.1 30.1 25.4 14.5 37.5 23.2 176.1 39.1 20.2 27.1 33.5 26.4 17.0 15.1 8.1 18.0 13.5 24.9 5.6 12.7 16.1 8.2 11.6 17.6 40.3 13.3 22.6 39.2 38.2 27.6 63.2 17.5 48.9 0.0 15.2 24.0 11.9 15.0 68.9 30.0 23.7 17.4 36.4 54.4 69.6 GP2 ZAP75 ENSG00000169347 "Glycoprotein 2" P55259 16 20309574-20327808 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 966 "pancreas: 35381.6" "Cell type enriched" "Detected in some" 5 "Exocrine glandular cells: 504.1" "Cancer enriched" "Detected in many" 14 "pancreatic cancer: 320.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015739, HPA016668" Enhanced "Secreted to digestive system" NA NA 41000 "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" "HPA015739: AB_1849905, HPA016668: AB_1849907" "unprognostic (2.14e-2)" "unprognostic (1.97e-2)" "unprognostic (5.68e-2)" "unprognostic (4.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.84e-1)" "unprognostic (6.35e-2)" "unprognostic (8.17e-3)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" 7.1 1.9 0.2 0.9 0.2 0.7 3.8 0.6 0.4 2.5 0.4 3.9 36.6 2.1 0.2 3.9 1.4 18.7 6.5 0.3 0.2 33.4 5.0 1.5 2.1 0.2 0.6 15.4 35381.6 0.0 2.9 2.4 0.3 33.4 6.2 0.1 7.5 0.0 1.6 1.8 10.1 0.1 0.1 2.5 27.4 1.9 0.2 0.1 1.3 0.0 0.2 1.0 1.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.6 0.4 0.3 0.2 0.2 0.6 0.3 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.2 1.1 0.1 0.1 87.2 0.0 0.0 0.0 0.0 0.0 1.7 9.8 1.3 7.5 0.3 0.5 0.2 0.0 0.0 0.0 504.1 0.0 0.2 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.1 0.0 0.0 0.3 15.6 0.3 0.4 0.0 0.0 4.2 0.2 0.0 0.0 0.0 20.7 13.9 0.4 0.0 69.7 2.0 0.0 0.0 0.3 0.0 0.5 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.1 19.9 2.1 GP6 GPVI ENSG00000088053 "Glycoprotein VI platelet" Q9HCN6 19 55013705-55038264 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Early spermatids: 14.3;Excitatory neurons: 9.9;Inhibitory neurons: 10.2;Late spermatids: 8.7;Macrophages: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HEL: 9.4;K-562: 4.1;U-2 OS: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047611, HPA066482" Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA 44000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "HPA047611: , HPA066482: AB_2685674" "unprognostic (3.06e-3)" "unprognostic (4.58e-2)" "unprognostic (1.74e-5)" "unprognostic (1.94e-1)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (7.50e-4)" "unprognostic (2.81e-1)" "unprognostic (1.00e-1)" "unprognostic (4.18e-2)" "unprognostic (3.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.53e-1)" "unprognostic (2.62e-1)" "unprognostic (3.32e-2)" "unprognostic (5.44e-3)" "unprognostic (2.70e-2)" 0.1 0.0 0.1 0.0 0.1 0.9 0.2 0.7 0.5 0.5 0.0 0.2 0.0 0.2 0.0 1.4 0.4 0.0 0.7 0.1 0.0 0.5 0.2 0.9 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 0.1 0.4 0.0 0.2 0.4 0.1 0.1 1.2 0.1 0.0 0.0 0.9 0.2 2.7 0.0 0.0 0.4 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.3 9.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 2.5 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.2 0.1 0.1 0.7 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.3 0.3 0.0 2.0 0.3 0.4 0.7 1.5 0.3 0.0 6.2 0.1 0.4 0.7 0.0 0.1 14.3 1.4 0.4 1.2 0.0 0.0 9.9 0.4 0.3 0.6 0.0 2.2 1.3 0.8 3.3 0.2 0.1 3.3 10.2 0.0 0.0 0.8 0.2 8.7 0.3 10.3 0.0 1.0 0.3 0.4 2.1 1.5 1.5 0.2 0.1 0.0 0.0 0.4 0.1 0.0 1.9 2.6 0.0 0.4 0.2 1.4 1.2 0.0 0.1 0.5 0.4 0.0 0.3 0.7 GPC2 "cerebroglycan, DKFZp547M109, FLJ38962" ENSG00000213420 "Glypican 2" Q8N158 7 100169606-100177381 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 5.2;skin 1: 5.7;testis: 11.9" "Cell type enhanced" "Detected in many" "Early spermatids: 37.7;Enteroendocrine cells: 10.7;Spermatocytes: 13.6" "Cancer enhanced" "Detected in many" "glioma: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 39.8;AN3-CA: 15.8;BEWO: 14.2;SH-SY5Y: 43.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB025423 Uncertain "Intracellular and membrane" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "CAB025423: " "unprognostic (4.33e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-4)" "unprognostic (3.42e-2)" "unprognostic (1.27e-1)" "unprognostic (2.36e-3)" "unprognostic (6.67e-2)" "unprognostic (1.15e-1)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-4)" "unprognostic (7.25e-4)" "unprognostic (1.67e-4)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (1.05e-1)" "prognostic favorable (9.94e-4)" 0.5 0.3 1.1 1.0 0.9 1.1 0.7 1.1 1.4 1.3 0.6 0.8 0.3 1.8 0.1 0.5 0.9 0.2 0.5 1.1 0.9 0.5 0.1 0.4 1.2 1.2 1.0 1.6 0.2 0.7 0.8 0.1 1.1 0.7 0.4 0.5 0.8 0.2 0.4 5.7 0.9 0.4 1.2 1.1 0.3 11.9 1.0 5.2 0.2 0.0 0.5 0.6 1.0 1.5 0.1 0.2 39.8 15.8 0.0 0.0 14.2 1.3 0.0 0.2 0.3 0.0 0.5 3.5 0.9 0.4 2.3 1.4 1.4 0.5 0.0 0.0 1.2 0.3 0.6 0.1 0.7 0.8 6.1 1.3 0.8 0.9 0.0 0.7 2.0 9.2 1.6 0.0 1.0 0.6 9.7 1.2 7.0 0.7 2.3 10.7 2.9 0.1 0.2 0.7 10.5 43.5 0.8 1.0 1.6 5.6 0.7 0.8 1.5 0.4 6.2 0.9 0.3 1.4 0.5 4.9 0.4 2.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 1.1 1.4 1.1 0.9 1.2 1.0 1.1 1.2 1.0 1.5 0.6 0.0 0.0 1.0 2.2 1.8 1.0 0.6 1.8 0.2 1.1 1.7 2.3 0.0 0.1 1.8 4.2 0.4 0.2 0.4 0.0 1.4 37.7 0.9 2.1 0.8 10.7 2.1 0.2 1.0 0.8 1.6 2.6 0.8 0.0 7.9 0.0 0.0 0.3 0.0 0.2 1.4 0.0 0.6 0.4 6.4 0.9 1.0 0.0 1.0 0.6 1.2 2.1 8.0 1.1 1.3 0.4 1.2 0.1 0.8 0.0 0.1 0.4 2.3 0.0 1.8 2.8 13.6 5.7 0.3 3.8 0.4 0.9 1.6 1.1 0.7 GPC5 ENSG00000179399 "Glypican 5" P78333 13 91398621-92873682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.1;kidney: 7.3;testis: 6.1" "Cell type enriched" "Detected in some" 20 "Astrocytes: 3868.1" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "CACO-2: 49.9;HeLa: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040152, HPA044081" Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm Cytosol "HPA040152: AB_2676863, HPA044081: AB_2678801" "unprognostic (4.99e-3)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (9.93e-5)" "prognostic unfavorable (4.37e-4)" "unprognostic (4.46e-1)" "unprognostic (1.93e-1)" "unprognostic (1.80e-2)" "unprognostic (9.49e-3)" "unprognostic (3.52e-2)" "unprognostic (1.21e-5)" "unprognostic (2.19e-2)" "unprognostic (1.82e-6)" "unprognostic (3.03e-2)" "unprognostic (2.43e-1)" "unprognostic (1.11e-1)" "unprognostic (6.69e-3)" 0.1 1.6 10.3 0.3 18.1 0.1 0.0 6.7 9.6 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.1 0.5 1.1 8.4 12.1 7.3 1.3 3.2 0.2 18.2 13.4 0.4 0.1 0.0 1.7 0.4 20.5 0.1 0.5 0.5 0.1 0.4 0.0 0.1 0.1 0.1 5.7 0.0 0.1 6.1 23.1 0.1 1.1 0.0 0.0 0.0 0.1 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.9 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 27.4 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.3 0.6 0.0 1.7 0.0 0.8 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.0 3.4 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.0 0.0 10.3 18.1 6.7 9.6 8.4 12.1 18.2 13.4 20.5 5.7 23.1 4.9 0.0 0.0 2.7 3868.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.1 0.0 0.1 64.6 0.0 1.6 0.0 0.0 0.1 0.0 0.0 116.6 0.0 0.0 0.4 0.0 0.1 0.0 7.9 0.0 0.0 0.1 0.0 190.6 0.1 0.0 0.0 0.4 1.0 0.3 0.1 0.0 118.0 0.6 0.0 0.0 127.2 20.9 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.7 0.8 0.3 0.1 0.0 0.0 0.1 0.1 0.5 0.0 0.1 GPC6 ENSG00000183098 "Glypican 6" Q9Y625 13 93226807-94408020 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 163.2;Excitatory neurons: 333.6;Inhibitory neurons: 496.1;Oligodendrocyte precursor cells: 691.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 62.5;HSkMC: 70.8;hTERT-RPE1: 64.3;SuSa: 39.5;U-87 MG: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA017671 Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 420000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA017671: AB_1849833" "unprognostic (5.24e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" "unprognostic (9.76e-2)" "unprognostic (1.72e-1)" "unprognostic (5.50e-2)" "unprognostic (1.28e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "unprognostic (2.66e-2)" "unprognostic (2.33e-2)" "unprognostic (3.71e-2)" "unprognostic (2.53e-3)" "unprognostic (6.21e-3)" "unprognostic (7.42e-2)" "unprognostic (3.36e-1)" "unprognostic (3.35e-3)" 9.1 2.2 0.8 8.9 1.9 0.1 2.2 1.7 1.5 3.6 1.1 6.3 2.3 2.4 2.4 5.2 4.1 17.0 6.2 1.3 3.1 7.7 17.7 3.5 0.4 1.7 2.4 7.3 1.6 1.8 2.9 1.3 2.3 6.2 6.5 5.6 3.1 15.1 0.6 1.1 4.3 7.8 2.0 2.2 5.4 2.0 1.9 1.7 1.7 1.9 0.9 11.6 2.4 2.1 0.0 4.7 10.2 4.5 62.5 19.5 0.0 7.2 0.0 4.9 6.4 0.0 0.0 0.2 0.0 16.0 0.0 0.0 5.7 1.2 9.1 0.0 4.1 0.0 0.1 20.2 37.8 0.1 0.1 70.8 0.5 11.7 8.1 64.3 0.0 0.0 0.0 0.1 6.9 0.0 0.0 0.1 6.4 0.0 3.4 0.0 1.6 0.1 5.5 0.0 4.1 16.8 0.0 1.9 0.0 39.5 14.0 0.0 0.0 26.9 22.6 25.4 12.3 15.9 0.1 0.0 52.8 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 1.9 1.7 1.5 1.3 3.1 1.7 2.4 2.3 2.0 1.9 2.1 0.6 0.0 0.5 163.2 0.0 0.6 0.5 0.5 0.6 50.3 0.6 1.9 1.7 4.3 0.7 7.3 10.4 0.2 0.0 0.1 0.0 0.3 6.7 1.6 25.9 1.1 0.0 0.0 333.6 0.0 0.1 31.2 0.0 3.1 0.0 36.0 5.7 41.2 0.5 0.0 496.1 0.1 2.0 1.3 1.0 5.0 4.7 0.5 1.8 31.9 0.0 2.7 0.0 691.6 13.2 0.1 0.0 1.9 0.1 1.6 0.0 14.5 0.0 115.0 0.0 34.4 20.9 4.2 2.7 0.5 0.4 0.1 0.7 11.9 0.1 0.2 GPD2 ENSG00000115159 "Glycerol-3-phosphate dehydrogenase 2" P43304 2 156435290-156613735 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 151.1;Late spermatids: 95.5;Oligodendrocyte precursor cells: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.3;eosinophil: 1.7;intermediate monocyte: 1.6;myeloid DC: 2.7;neutrophil: 1.1;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.7;granulocytes: 1.7;monocytes: 3.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008012, HPA045506" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA 620000 "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria "HPA008012: AB_1079013, HPA045506: AB_2679355" "unprognostic (1.30e-1)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (4.79e-3)" "unprognostic (3.25e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (2.60e-3)" "unprognostic (6.67e-2)" "unprognostic (6.02e-3)" "unprognostic (1.73e-1)" "unprognostic (1.89e-1)" "unprognostic (2.41e-1)" "unprognostic (1.01e-2)" 8.2 5.7 13.3 8.1 17.7 13.4 16.2 15.2 18.6 10.3 6.5 18.6 14.4 6.8 5.2 20.3 18.2 8.9 6.2 19.8 16.3 8.0 3.4 11.4 7.0 13.5 16.2 8.6 6.8 20.5 5.5 6.7 13.1 10.9 18.0 9.6 14.9 7.1 24.7 12.5 15.7 6.1 14.5 8.5 17.4 5.5 18.5 6.1 12.2 14.3 8.6 14.3 9.5 13.6 39.0 27.2 15.3 24.5 32.6 39.6 0.1 48.0 31.2 32.1 38.6 53.9 35.7 8.4 31.9 27.4 13.2 44.5 28.9 44.5 41.4 23.9 9.5 6.0 46.9 0.0 12.0 11.2 12.6 19.5 15.4 55.6 27.1 20.6 24.1 3.7 12.0 1.9 41.7 24.4 0.3 1.0 28.7 15.2 31.0 12.3 9.8 9.2 41.8 50.7 27.3 9.9 45.0 34.4 30.4 25.9 10.9 30.8 22.8 5.7 26.9 26.5 36.5 1.3 0.3 0.4 32.9 3.0 47.1 0.3 3.3 1.7 0.3 1.6 0.5 0.1 0.1 0.4 2.7 0.2 0.3 0.2 1.1 0.4 2.3 0.3 0.5 1.5 13.3 17.7 15.2 18.6 19.8 16.3 13.5 16.2 13.1 14.5 18.5 13.6 12.1 19.2 12.3 151.1 7.8 20.0 23.3 24.9 21.1 5.5 23.4 12.8 13.1 7.2 19.8 22.0 6.2 9.6 6.2 52.1 1.9 9.5 84.8 12.3 6.1 11.3 17.4 6.9 27.9 13.4 15.2 9.2 30.5 23.3 12.7 13.0 10.4 3.4 21.3 5.0 46.9 17.1 10.2 18.6 18.7 95.5 12.2 21.0 24.9 61.8 10.8 4.2 4.1 148.3 48.7 16.2 17.4 7.2 5.6 66.7 16.0 3.9 18.2 11.1 0.0 8.3 12.3 2.6 3.2 41.7 21.5 11.1 7.6 7.0 19.4 77.8 GPER1 "CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR" ENSG00000164850 "G protein-coupled estrogen receptor 1" Q99527 7 1082208-1093815 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 45.3" "Cell type enhanced" "Detected in many" "Adipocytes: 9.6;Distal enterocytes: 15.4;Endothelial cells: 11.3;Hepatocytes: 23.5;Kupffer cells: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.9;intermediate monocyte: 2.8;myeloid DC: 5.8" "Group enriched" "Detected in many" 19 "dendritic cells: 5.8;monocytes: 2.9" "Cell line enhanced" "Detected in many" "AN3-CA: 11.5;Daudi: 12.1;fHDF/TERT166: 8.6;Hep G2: 22.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016718, HPA027052" Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoli "Nucleoplasm, Vesicles, Cytosol" "HPA016718: , HPA027052: AB_10612112" "unprognostic (4.74e-2)" "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "prognostic favorable (1.17e-4)" "unprognostic (2.17e-1)" "unprognostic (6.17e-2)" "unprognostic (3.45e-1)" "unprognostic (6.38e-2)" "unprognostic (2.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (2.49e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-2)" "unprognostic (1.58e-1)" "unprognostic (7.26e-2)" "unprognostic (7.78e-2)" 10.6 12.6 12.7 1.5 11.7 0.2 8.4 9.0 15.9 5.4 8.1 10.8 0.6 5.8 0.3 2.2 4.3 1.2 7.1 10.0 9.6 9.7 27.9 12.1 1.9 9.9 10.2 2.4 2.1 0.4 6.1 6.3 10.5 7.2 1.4 0.9 2.9 5.0 4.3 2.8 3.6 1.8 8.4 8.5 45.3 1.5 11.6 0.9 9.7 1.3 1.0 6.1 4.7 9.2 1.1 0.4 0.3 11.5 2.7 2.6 1.1 6.7 4.4 2.1 3.7 0.2 0.3 12.1 1.1 8.6 0.1 0.6 0.1 0.0 0.2 2.6 2.1 0.0 1.4 22.8 0.4 0.1 0.7 1.5 0.0 1.3 0.0 1.6 0.6 0.2 0.1 0.1 0.5 0.8 0.0 0.4 2.2 2.4 7.9 1.1 0.0 0.0 0.2 0.0 0.1 4.5 0.0 0.5 2.5 0.8 0.2 0.1 1.6 0.4 2.8 6.9 2.1 0.0 0.0 4.4 3.8 0.2 0.2 0.0 2.9 0.0 0.0 2.8 0.0 0.2 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.4 12.7 11.7 9.0 15.9 10.0 9.6 9.9 10.2 10.5 8.4 11.6 9.2 9.6 0.0 0.0 1.0 1.2 0.5 0.0 0.5 1.8 0.0 0.5 0.5 2.8 0.0 0.0 5.5 0.0 0.0 0.0 15.4 0.0 0.1 0.0 4.4 0.1 11.3 1.2 0.0 0.8 3.1 0.6 1.5 0.5 1.0 0.0 0.4 1.1 23.5 0.6 0.0 0.5 2.8 0.0 16.9 2.7 0.7 2.8 2.9 0.0 1.9 0.6 4.4 0.0 0.5 0.1 0.8 7.4 1.2 0.1 0.8 0.2 5.6 0.0 0.4 0.0 0.7 7.2 0.5 2.7 0.1 0.3 0.0 0.0 0.1 2.0 0.1 GPHA2 "A2, GPA2, MGC126572, ZSIG51" ENSG00000149735 "Glycoprotein hormone subunit alpha 2" Q96T91 11 64934471-64935893 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "pancreas: 360.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.5;Exocrine glandular cells: 17.4;Pancreatic endocrine cells: 2.4;Spermatocytes: 7.7;Spermatogonia: 3.2" "Cancer enriched" "Detected in some" 7 "testis cancer: 15.8" "Region enhanced" "Detected in single" "cerebellum: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "Hep G2: 21.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067068 Approved Vesicles "Secreted to blood" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA067068: " "unprognostic (1.13e-1)" "unprognostic (8.31e-3)" "unprognostic (1.51e-2)" "unprognostic (9.22e-4)" "unprognostic (7.88e-3)" "unprognostic (2.62e-1)" "unprognostic (1.45e-1)" "unprognostic (3.20e-2)" "unprognostic (1.82e-1)" "unprognostic (1.75e-1)" "unprognostic (5.03e-2)" "unprognostic (9.86e-3)" "unprognostic (1.70e-1)" 0.0 0.1 0.3 0.2 0.6 0.1 0.1 3.6 0.6 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.4 16.9 0.0 0.3 0.3 0.8 0.7 0.3 0.6 0.4 0.3 2.7 360.5 0.0 28.0 0.0 0.6 0.7 0.0 0.1 0.3 0.5 0.0 0.5 0.5 0.0 0.2 0.6 1.1 10.8 0.4 0.1 0.3 0.0 0.5 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 21.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 3.6 0.6 0.3 0.3 0.4 0.3 0.6 0.2 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 17.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 0.0 0.0 7.7 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 GPHB5 "GPB5, ZLUT1" ENSG00000179600 "Glycoprotein hormone subunit beta 5" Q86YW7 14 63312835-63318935 "Predicted secreted proteins" Hormone "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPIHBP1 "GPI-HBP1, LOC338328" ENSG00000277494 "Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1" Q8IV16 8 143213218-143217170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.7;breast: 54.5" "Cell type enriched" "Detected in some" 4 "Adipocytes: 356.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Karpas-707: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066302 Enhanced "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA066302: AB_2685654" "unprognostic (2.05e-1)" "unprognostic (3.11e-2)" "unprognostic (1.71e-3)" "unprognostic (2.43e-3)" "unprognostic (1.58e-1)" "unprognostic (9.50e-2)" "unprognostic (1.75e-3)" "unprognostic (8.01e-2)" "unprognostic (2.04e-1)" "unprognostic (1.30e-1)" "unprognostic (9.31e-2)" "unprognostic (8.69e-2)" "unprognostic (5.06e-3)" "unprognostic (9.65e-3)" "unprognostic (1.41e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-3)" 90.7 4.9 12.9 0.4 23.7 0.1 54.5 22.7 27.2 8.7 7.5 5.3 0.6 11.4 0.2 3.5 11.7 6.5 38.6 13.3 17.9 11.0 1.6 27.4 2.4 35.8 20.8 6.6 1.8 1.1 3.4 6.5 32.9 3.9 0.5 0.1 4.1 1.6 30.2 7.4 3.7 2.4 18.0 19.3 4.1 2.0 22.8 1.9 5.5 29.7 1.0 10.5 7.9 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 23.7 22.7 27.2 13.3 17.9 35.8 20.8 32.9 18.0 22.8 53.5 356.5 0.0 3.2 0.0 0.5 1.5 0.1 0.0 1.2 0.0 1.0 0.6 4.3 0.0 0.6 0.0 0.0 0.0 1.3 0.0 1.9 0.0 0.1 0.0 0.0 77.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 1.3 0.0 35.7 0.4 0.0 0.0 0.1 0.0 0.0 0.8 2.1 0.6 1.5 0.4 0.0 8.4 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 5.4 3.0 0.0 0.7 0.2 1.1 0.0 0.4 1.1 0.0 0.2 GPLD1 ENSG00000112293 "Glycosylphosphatidylinositol specific phospholipase D1" P80108 6 24424565-24495205 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 46.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 68.8;Excitatory neurons: 62.4;Hepatocytes: 66.8;Inhibitory neurons: 78.3;Oligodendrocyte precursor cells: 33.2" "Cancer enriched" "Detected in some" 11 "liver cancer: 6.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 7.6;U-698: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008625, HPA012500" Uncertain "Secreted to blood" NA NA 103000000000 3100000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB008625: AB_1621070, HPA012500: AB_1849931" "unprognostic (6.80e-3)" "unprognostic (2.27e-1)" "unprognostic (1.59e-1)" "unprognostic (4.81e-5)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.37e-4)" "unprognostic (7.93e-2)" "unprognostic (2.86e-2)" "unprognostic (6.07e-4)" "unprognostic (2.68e-1)" "unprognostic (5.28e-4)" "unprognostic (2.20e-1)" "unprognostic (9.98e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" 4.2 0.9 2.0 0.6 1.7 0.9 1.3 7.6 4.7 1.1 0.1 1.0 0.5 1.6 1.7 1.1 0.9 0.6 0.5 1.3 2.4 0.6 46.1 0.9 0.9 1.8 1.9 1.2 0.6 2.5 1.7 0.2 1.9 1.8 0.6 6.2 0.4 4.8 1.7 8.6 0.4 1.4 0.6 0.6 0.7 1.4 1.4 5.1 2.4 0.6 1.3 1.1 1.5 2.1 0.5 0.7 0.8 1.2 0.0 0.0 2.0 0.1 0.2 0.2 0.1 3.5 0.1 7.6 0.8 0.1 0.2 0.1 1.2 0.2 0.1 0.9 2.1 1.1 0.9 3.2 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.8 0.0 1.8 0.5 0.3 0.1 0.5 0.7 0.5 2.9 0.5 0.3 1.4 0.2 0.1 0.4 3.4 2.0 2.3 0.9 0.1 0.4 0.6 0.4 0.3 0.1 0.7 0.9 0.1 1.0 2.4 3.4 8.1 0.1 0.3 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.0 2.0 1.7 7.6 4.7 1.3 2.4 1.8 1.9 1.9 0.6 1.4 2.1 0.4 0.0 3.7 24.8 1.1 0.0 0.7 2.8 0.6 19.6 0.7 0.4 11.6 0.0 1.7 1.8 68.8 0.3 1.6 0.1 0.0 0.4 3.5 0.5 0.6 1.2 1.8 7.4 62.4 0.4 0.3 1.3 0.0 0.3 0.0 2.1 1.4 66.8 0.1 15.2 78.3 0.3 0.0 1.3 0.0 3.4 3.1 0.1 0.0 9.4 0.1 4.0 3.1 33.2 3.1 0.1 0.1 3.4 3.1 0.3 0.1 0.5 1.1 10.9 0.0 3.6 1.4 0.5 5.8 0.3 0.6 0.0 0.5 0.9 0.5 2.6 GPN3 "ATPBD1C, MGC14560" ENSG00000111231 "GPN-loop GTPase 3" Q9UHW5 12 110452486-110469268 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039764, HPA047793" Uncertain Approved "Nuclear speckles,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" Cytosol "HPA039764: AB_2676669, HPA047793: AB_2680157" "unprognostic (1.68e-3)" "unprognostic (1.11e-2)" "unprognostic (9.82e-2)" "unprognostic (4.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.27e-3)" "prognostic unfavorable (3.98e-5)" "unprognostic (5.50e-2)" "unprognostic (4.45e-2)" "unprognostic (2.70e-1)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" "prognostic favorable (2.65e-6)" "unprognostic (5.81e-2)" "unprognostic (2.85e-1)" "unprognostic (1.62e-1)" "unprognostic (2.27e-1)" 25.6 18.9 10.4 16.3 11.7 15.4 24.4 12.9 12.9 15.7 11.6 15.6 8.1 17.8 15.2 16.3 18.5 13.8 34.2 10.0 11.0 31.4 32.1 16.9 22.9 12.2 11.2 23.3 19.9 29.2 11.1 21.3 12.8 22.2 13.1 23.4 24.2 18.0 47.9 11.1 10.6 19.5 13.0 16.2 15.6 41.3 10.9 18.1 21.2 51.1 18.1 17.6 13.8 14.9 42.3 65.8 43.2 42.8 47.5 30.1 57.6 57.1 34.1 62.2 50.3 59.7 24.6 81.5 38.5 31.0 46.0 37.9 54.2 50.5 83.9 46.9 50.6 47.7 33.8 50.5 33.2 75.2 42.2 32.2 31.4 61.1 39.5 34.9 45.6 67.0 82.1 17.9 44.3 28.2 69.8 142.8 53.4 58.6 64.8 23.5 59.9 62.2 39.3 37.8 34.7 34.8 57.7 39.0 49.9 55.0 66.7 87.7 25.4 51.6 38.0 51.3 66.6 24.7 68.0 85.1 38.2 68.5 60.3 41.0 54.4 79.4 30.0 71.9 32.8 46.5 32.0 34.2 51.1 47.9 40.5 26.9 27.4 28.4 75.3 62.5 30.1 41.6 10.4 11.7 12.9 12.9 10.0 11.0 12.2 11.2 12.8 13.0 10.9 14.9 23.8 25.6 34.5 3.3 24.5 29.8 49.3 57.9 15.9 18.8 28.8 32.5 43.8 20.0 36.0 33.1 14.6 62.4 26.6 3.8 107.6 30.4 111.1 24.9 24.6 20.8 8.3 26.9 4.3 21.3 74.0 25.4 8.2 21.5 31.0 18.6 18.2 38.1 94.7 21.9 5.6 9.1 40.7 19.1 17.7 22.6 19.9 33.2 16.0 14.0 39.6 25.7 19.6 3.5 6.4 22.4 11.0 23.7 20.9 55.5 5.3 72.1 34.2 33.0 26.3 31.0 35.3 187.2 77.6 20.8 25.4 46.7 19.2 22.1 13.7 40.2 GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 581.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 327.1;Fibroblasts: 285.8;Hofbauer cells: 814.1;Macrophages: 328.9;Melanocytes: 597.7;Suprabasal keratinocytes: 359.7" "Cancer enhanced" "Detected in all" "melanoma: 354.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cell line enriched" "Detected in many" 6 "ASC diff: 5015.0" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 33000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.65e-2)" "unprognostic (1.82e-1)" "unprognostic (5.14e-2)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (3.89e-2)" "unprognostic (7.13e-2)" "unprognostic (2.79e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (2.08e-3)" "unprognostic (1.24e-2)" "unprognostic (3.46e-2)" "unprognostic (4.82e-1)" "unprognostic (6.95e-2)" 152.9 25.9 20.9 41.7 20.9 6.6 135.6 19.0 70.9 303.9 77.6 78.8 22.5 180.9 43.8 111.8 72.8 270.7 323.5 21.2 23.1 32.7 52.5 215.8 169.0 32.2 21.5 77.7 20.6 15.3 12.8 148.6 31.0 30.4 92.9 2.9 66.1 55.8 15.4 581.2 48.5 151.5 27.3 31.9 37.1 26.2 34.6 89.5 51.5 72.4 103.4 190.9 151.0 66.5 19.2 0.8 0.1 0.6 5015.0 908.0 0.4 33.6 564.1 27.9 116.2 0.2 0.8 0.7 1.4 109.5 49.1 118.3 0.7 0.7 14.2 1.3 1.3 0.1 0.9 2.5 61.5 1.5 0.6 630.3 134.8 46.3 4.7 734.9 0.3 1.4 0.3 0.6 150.2 3.5 0.7 0.7 0.6 0.5 0.5 0.4 1.4 7.6 71.2 443.4 2.4 0.6 0.1 175.6 841.5 1.3 2.3 2.8 0.1 163.0 17.8 297.8 5.5 5.1 8.6 1.2 56.3 2.6 166.1 0.6 2.1 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.1 0.1 0.4 0.0 0.5 20.9 20.9 19.0 70.9 21.2 23.1 32.2 21.5 31.0 27.3 34.6 66.5 18.0 19.2 24.3 0.3 3.2 327.1 7.1 58.5 150.2 0.4 6.6 24.5 204.2 2.8 16.0 75.4 0.0 7.2 2.2 0.1 3.9 0.6 3.0 2.5 44.0 15.0 0.0 0.0 0.5 0.8 4.6 285.8 12.2 2.5 22.7 0.1 4.6 5.1 814.1 1.7 1.2 0.0 12.2 188.4 100.7 5.5 129.8 328.9 597.7 12.2 3.2 0.2 1.0 55.8 0.1 0.6 0.0 108.0 10.2 1.9 0.0 1.2 3.4 0.6 0.0 20.6 53.4 3.9 1.4 65.3 359.7 28.9 5.7 0.1 0.0 11.9 GPR108 LUSTR2 ENSG00000125734 "G protein-coupled receptor 108" Q9NPR9 19 6729914-6737603 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041924, HPA041951, HPA063863" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" Vesicles "HPA041924: AB_10804122, HPA041951: AB_10795385, HPA063863: AB_2685135" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (1.07e-1)" "prognostic favorable (1.04e-7)" "unprognostic (1.58e-1)" "unprognostic (5.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (4.23e-2)" "unprognostic (3.01e-2)" "unprognostic (7.89e-2)" "unprognostic (3.57e-2)" "prognostic favorable (1.29e-9)" "unprognostic (8.68e-3)" "unprognostic (2.95e-2)" "unprognostic (4.96e-3)" "unprognostic (4.13e-3)" 29.9 45.2 26.9 18.8 29.3 26.2 32.7 29.7 27.2 36.8 29.9 39.9 32.9 31.6 31.6 39.6 40.1 32.2 22.5 24.2 29.4 42.1 34.4 32.4 23.2 28.9 28.1 34.5 46.7 49.0 23.2 22.2 27.5 34.4 28.1 27.8 57.5 40.2 18.4 31.2 36.6 26.3 27.7 33.3 35.8 25.5 29.1 23.5 41.3 20.5 27.8 31.0 32.9 27.8 33.5 35.9 21.7 42.6 83.0 44.8 24.4 25.6 77.0 34.7 36.7 22.2 37.5 15.8 46.4 52.4 41.6 28.1 24.7 53.3 17.8 64.1 28.4 25.7 37.7 29.6 81.3 16.7 33.7 48.7 100.2 33.5 67.2 45.9 41.3 37.9 26.4 102.7 35.6 23.3 29.5 24.0 15.6 60.2 31.5 23.7 24.7 61.0 72.7 32.6 0.2 23.4 25.9 41.8 38.7 18.4 39.9 40.0 34.4 19.7 12.5 63.2 27.6 66.2 39.3 11.4 68.0 52.9 21.7 79.3 116.1 123.0 82.6 109.7 75.2 48.2 65.2 70.4 84.6 49.9 45.9 52.8 178.4 80.9 130.5 30.0 81.2 132.7 26.9 29.3 29.7 27.2 24.2 29.4 28.9 28.1 27.5 27.7 29.1 27.8 40.8 9.6 14.5 12.7 26.3 26.5 43.7 107.4 21.1 28.3 42.7 33.0 8.0 45.8 59.7 36.8 22.9 58.7 31.1 76.4 37.2 87.7 38.0 30.8 23.6 32.7 21.7 6.9 5.4 110.1 37.2 27.4 39.3 44.1 26.0 15.0 40.7 26.7 57.1 21.9 6.0 57.6 81.4 30.3 46.7 94.9 23.6 42.4 30.2 5.6 50.3 46.0 42.2 7.5 9.6 83.3 83.7 18.4 27.8 29.1 121.2 55.0 39.8 43.0 39.5 22.2 26.4 34.3 19.9 27.2 31.8 58.6 38.9 28.3 47.1 36.1 GPR146 PGR8 ENSG00000164849 "G protein-coupled receptor 146" Q96CH1 7 1044546-1059261 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "adipose tissue: 47.9" "Cell type enhanced" "Detected in many" "Adipocytes: 96.3;Endothelial cells: 45.3;Extravillous trophoblasts: 243.2;Syncytiotrophoblasts: 82.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 95.2;naive CD4 T-cell: 25.6" "Group enriched" "Detected in many" 4 "granulocytes: 95.2;T-cells: 25.6" "Cell line enhanced" "Detected in many" "BEWO: 23.0;NB-4: 7.1" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (3.39e-2)" "unprognostic (7.83e-2)" "unprognostic (6.27e-4)" "unprognostic (5.51e-3)" "unprognostic (1.78e-1)" "unprognostic (2.33e-1)" "unprognostic (2.30e-1)" "unprognostic (2.69e-1)" "unprognostic (2.99e-2)" "unprognostic (3.48e-3)" "unprognostic (2.51e-2)" "unprognostic (1.70e-1)" "unprognostic (1.14e-1)" "unprognostic (3.27e-3)" "unprognostic (1.41e-1)" "unprognostic (4.19e-2)" "unprognostic (1.03e-2)" 47.9 2.6 16.9 2.0 17.2 9.0 41.8 17.0 20.9 10.0 22.1 14.1 2.8 13.2 2.8 4.7 12.3 7.5 13.2 13.6 15.4 5.3 20.4 24.9 4.1 18.6 18.4 7.4 5.9 1.6 3.4 10.2 18.7 7.2 1.0 3.6 9.6 5.5 10.7 11.2 8.1 3.5 16.6 6.7 12.9 2.6 21.8 1.7 11.5 8.8 1.2 13.2 8.7 17.3 1.2 1.0 0.4 1.0 1.3 0.3 23.0 0.1 0.9 0.2 1.1 0.8 1.1 0.4 0.7 0.1 3.5 0.8 0.0 0.3 0.1 0.8 0.9 1.7 0.7 1.9 1.5 0.1 0.2 0.5 0.0 0.7 0.0 2.4 1.7 0.6 1.1 1.2 0.2 0.7 0.0 7.1 1.6 1.3 0.6 5.5 0.0 1.5 0.3 0.1 1.2 1.7 1.8 0.2 2.0 0.9 1.1 2.2 0.5 1.0 1.1 1.6 0.8 1.9 2.1 0.1 6.1 2.2 2.1 0.0 0.2 95.2 0.6 0.1 1.2 0.0 8.4 0.7 1.7 0.1 25.6 4.8 0.1 1.3 0.3 14.3 14.5 4.3 16.9 17.2 17.0 20.9 13.6 15.4 18.6 18.4 18.7 16.6 21.8 17.3 96.3 0.0 2.8 7.2 3.3 1.8 0.8 1.8 1.2 3.7 7.6 3.4 0.3 1.5 2.1 1.8 0.0 9.3 1.4 0.3 1.9 1.0 0.1 3.2 0.4 45.3 4.2 30.5 0.9 0.6 243.2 4.8 2.0 3.7 2.5 1.7 16.4 21.3 10.9 3.3 1.4 0.3 2.0 0.6 6.1 1.1 3.1 1.7 3.6 3.7 0.2 21.2 2.1 4.5 1.7 0.7 0.3 3.4 0.9 0.7 0.8 3.4 0.0 5.7 0.0 2.3 1.4 0.5 1.5 0.4 2.3 82.4 2.5 0.9 1.0 0.4 GPR162 "A-2, GRCA" ENSG00000250510 "G protein-coupled receptor 162" Q16538 12 6821624-6829972 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 180.3;choroid plexus: 108.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 86.3;Excitatory neurons: 36.8;Horizontal cells: 40.4;Inhibitory neurons: 32.9;Muller glia cells: 55.9;Respiratory ciliated cells: 56.2" "Cancer enriched" "Detected in many" 6 "glioma: 16.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 6.9;intermediate monocyte: 4.3;neutrophil: 17.4" "Group enriched" "Detected in many" 6 "granulocytes: 17.4;monocytes: 6.9" "Cell line enhanced" "Detected in many" "AF22: 17.7;AN3-CA: 21.1;hTERT-RPE1: 18.1;NTERA-2: 19.8;SH-SY5Y: 13.5;U-2 OS: 16.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055135 Enhanced Approved "Centriolar satellite" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Centriolar satellite" "HPA055135: AB_2682710" "unprognostic (4.76e-2)" "unprognostic (8.00e-2)" "unprognostic (8.24e-3)" "unprognostic (1.31e-2)" "unprognostic (1.31e-1)" "unprognostic (2.38e-1)" "unprognostic (4.78e-2)" "unprognostic (2.25e-2)" "unprognostic (5.83e-3)" "unprognostic (1.18e-1)" "prognostic favorable (4.29e-5)" "unprognostic (3.82e-3)" "prognostic unfavorable (1.37e-6)" "unprognostic (3.10e-3)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (3.64e-2)" 5.1 6.8 116.5 4.4 122.2 1.3 2.7 111.7 180.3 5.8 108.2 15.2 3.1 7.6 2.5 2.3 18.3 5.9 10.9 138.2 106.4 5.6 6.2 17.6 1.5 100.8 100.5 5.8 2.5 10.6 31.7 4.4 101.0 5.8 2.7 20.6 1.4 1.7 1.5 1.4 8.0 5.9 93.3 6.6 5.0 1.5 106.2 1.4 2.8 1.1 0.7 7.2 2.8 117.4 0.0 3.9 17.7 21.1 1.9 1.3 0.1 1.3 4.6 3.9 2.3 0.4 0.0 0.0 0.1 2.6 0.1 0.1 2.8 0.0 1.9 0.0 1.3 2.1 0.2 0.0 3.0 0.4 0.0 3.2 0.0 6.0 0.3 18.1 10.9 1.6 1.0 0.1 1.5 0.0 0.5 1.5 19.8 0.0 0.1 0.0 2.2 3.9 1.3 0.0 1.5 13.5 0.0 0.0 0.6 12.0 0.1 5.3 7.4 2.7 16.1 1.4 2.5 0.0 1.3 0.1 2.9 3.8 0.3 0.0 6.9 0.0 0.0 4.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 17.4 0.0 1.5 1.7 0.0 1.9 116.5 122.2 111.7 180.3 138.2 106.4 100.8 100.5 101.0 93.3 106.2 117.4 0.5 0.0 0.0 11.8 0.3 0.8 0.2 2.3 0.0 86.3 3.6 1.3 3.8 1.5 2.6 1.8 4.2 0.1 0.0 0.0 1.9 0.0 0.1 9.3 5.6 3.5 0.0 0.4 36.8 0.0 0.1 2.9 0.0 0.3 0.0 0.6 6.1 1.5 2.6 40.4 32.9 0.0 2.0 3.7 3.4 0.6 7.5 5.2 0.0 6.5 4.2 55.9 0.0 23.1 3.7 0.1 0.0 14.7 0.1 0.5 0.0 1.9 56.2 9.0 0.0 0.5 8.1 0.0 0.2 0.2 0.1 0.3 0.2 1.3 0.1 0.1 GPR19 ENSG00000183150 "G protein-coupled receptor 19" Q15760 12 12660890-12696207 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.3;pituitary gland: 7.8" "Cell type enhanced" "Detected in some" "Astrocytes: 7.8;Excitatory neurons: 15.2;Inhibitory neurons: 15.6;Oligodendrocyte precursor cells: 15.6;Oligodendrocytes: 5.9" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 6.5" "Group enriched" "Detected in many" 15 "granulocytes: 2.9;T-cells: 6.5" "Cell line enhanced" "Detected in many" "HDLM-2: 39.9;NTERA-2: 39.7;SuSa: 28.5;WM-115: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013955 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA013955: AB_1849287" "unprognostic (1.92e-1)" "unprognostic (3.38e-2)" "unprognostic (1.72e-1)" "unprognostic (8.62e-5)" "unprognostic (1.60e-1)" "unprognostic (3.21e-1)" "unprognostic (8.25e-4)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" "unprognostic (6.90e-2)" "unprognostic (1.45e-1)" "unprognostic (1.70e-2)" "unprognostic (2.67e-12)" "unprognostic (5.19e-2)" "unprognostic (1.38e-1)" "unprognostic (7.60e-2)" "unprognostic (1.60e-1)" 0.3 0.8 7.2 2.0 7.3 0.9 0.3 9.1 10.3 0.1 3.6 0.5 0.3 0.1 0.1 0.5 0.2 0.3 0.1 7.0 9.1 0.1 0.2 0.2 1.8 6.3 6.8 0.0 0.3 0.1 7.8 0.3 6.9 0.1 0.6 2.0 0.1 0.1 0.0 0.8 0.5 0.3 7.0 0.7 0.4 4.3 7.6 2.8 0.1 0.0 2.4 0.3 0.1 6.9 1.6 0.6 16.6 0.4 0.0 0.0 7.0 1.6 1.7 2.9 2.5 6.6 10.1 6.8 2.5 1.2 2.3 1.3 2.7 0.3 4.8 39.9 0.3 1.6 0.7 1.1 0.0 1.7 0.6 0.1 0.0 3.1 1.9 1.2 0.5 0.7 0.3 13.8 0.6 2.4 0.6 1.0 39.7 1.7 3.0 4.4 2.5 0.2 0.2 1.4 5.4 5.0 0.7 1.4 13.4 28.5 0.9 1.7 0.0 0.8 7.2 1.3 3.9 7.6 7.2 13.3 3.1 4.7 20.4 0.0 0.0 0.0 1.2 0.0 0.8 0.2 2.4 1.4 0.0 0.1 0.4 0.9 2.9 0.3 0.0 0.0 6.5 0.3 7.2 7.3 9.1 10.3 7.0 9.1 6.3 6.8 6.9 7.0 7.6 6.9 0.2 0.0 0.0 7.8 0.4 0.1 0.1 0.0 0.0 1.8 0.4 0.5 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 4.7 0.1 0.2 0.1 0.0 2.7 15.2 0.0 0.3 0.1 0.0 0.1 0.0 0.2 0.4 0.2 0.1 0.0 15.6 0.1 0.0 0.3 0.3 1.6 0.3 0.2 0.0 2.8 0.0 1.7 0.0 15.6 5.9 0.2 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.8 3.6 0.6 0.0 0.0 0.1 1.2 0.0 0.3 0.1 GPRC5B RAIG-2 ENSG00000167191 "G protein-coupled receptor class C group 5 member B" Q9NZH0 16 19856691-19886167 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 490.3" "Cell type enhanced" "Detected in many" "Early spermatids: 197.7;Late spermatids: 269.9;Oligodendrocytes: 171.0" "Cancer enhanced" "Detected in all" "glioma: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.8" "Lineage enhanced" "Detected in single" "T-cells: 2.8" "Cell line enhanced" "Detected in many" "EFO-21: 92.5;HHSteC: 60.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015247 Enhanced Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 34: Spermatids - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA015247: AB_1849323" "unprognostic (1.26e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.60e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (3.97e-2)" "unprognostic (5.70e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.30e-4)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.42e-3)" "unprognostic (6.78e-3)" 25.3 7.0 249.1 4.4 428.3 0.1 19.6 365.2 263.4 12.8 13.1 8.1 5.7 13.1 14.8 8.1 20.1 15.3 40.7 245.8 278.4 22.4 3.2 5.8 7.8 379.4 327.1 22.6 21.7 45.9 14.1 15.7 333.0 9.6 2.4 17.4 40.1 17.7 72.7 7.5 11.1 7.5 262.7 2.5 41.3 34.0 315.0 3.2 13.8 73.8 3.4 12.8 8.6 490.3 1.2 29.9 29.0 5.2 29.3 2.0 5.3 0.3 7.4 2.9 1.8 28.0 1.0 0.0 92.5 1.0 18.9 1.6 21.6 0.2 1.7 0.2 8.6 0.0 0.1 0.0 60.3 0.0 0.0 2.5 0.0 4.9 0.0 7.9 14.3 0.7 6.6 0.6 6.7 1.5 0.1 0.1 31.8 0.0 15.6 8.9 0.0 0.2 1.1 13.8 22.9 1.9 3.6 1.9 27.2 9.1 0.1 0.6 2.9 0.0 3.5 14.4 0.8 0.4 0.1 0.3 1.4 0.3 1.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.5 249.1 428.3 365.2 263.4 245.8 278.4 379.4 327.1 333.0 262.7 315.0 490.3 71.4 0.0 3.0 75.4 1.2 1.3 5.3 2.6 9.1 30.7 22.5 16.3 15.7 40.0 7.2 31.3 0.0 5.0 0.3 0.2 1.9 65.3 197.7 4.1 20.7 44.8 0.0 0.0 2.4 64.5 1.4 14.8 31.6 13.7 0.0 0.4 9.3 0.2 4.1 0.0 13.5 0.0 38.7 1.6 2.6 269.9 23.9 2.2 16.0 7.5 1.0 24.8 0.0 51.8 171.0 72.8 0.0 26.7 1.3 12.3 0.0 0.3 3.3 6.0 13.1 3.3 13.0 4.9 1.6 2.4 1.7 2.5 0.8 7.0 0.2 1.6 GPRC5C RAIG-3 ENSG00000170412 "G protein-coupled receptor class C group 5 member C" Q9NQ84 17 74424851-74451653 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 192.7;stomach 1: 230.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 211.3;Gastric mucus-secreting cells: 143.2;Hepatocytes: 183.6;Paneth cells: 153.8;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 7.9" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;monocytes: 3.7" "Cell line enhanced" "Detected in many" "Hep G2: 82.4;HMC-1: 146.7;PC-3: 80.8;RPTEC TERT1: 172.1;RT4: 89.9;T-47d: 108.0" "Region enriched" "Detected in all" 9 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA029776 Enhanced Uncertain "Nucleoplasm,Centriolar satellite,Cytosol" NA Yes 15000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA029776: AB_10602324" "unprognostic (1.48e-1)" "unprognostic (3.35e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-3)" "unprognostic (1.80e-2)" "unprognostic (1.09e-2)" "unprognostic (4.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (9.61e-3)" "unprognostic (1.05e-1)" "prognostic favorable (1.58e-5)" "unprognostic (7.58e-2)" "unprognostic (3.70e-2)" "unprognostic (2.75e-2)" "unprognostic (1.54e-3)" 16.1 19.3 17.4 3.1 18.4 0.4 20.1 48.9 18.1 42.0 28.0 38.7 25.0 17.1 10.2 12.2 30.0 21.3 33.7 14.8 16.9 135.7 192.7 23.0 2.1 18.1 18.7 38.2 136.1 28.2 14.8 11.9 18.6 45.6 14.6 1.5 37.4 24.3 110.1 43.9 30.3 4.0 16.6 22.3 230.3 4.0 17.0 4.4 74.8 33.9 3.0 30.8 20.9 15.7 17.3 61.6 3.8 5.5 0.0 0.0 0.2 0.3 0.0 0.0 0.0 66.4 73.0 0.0 45.0 0.3 18.5 52.9 7.7 1.0 0.1 0.2 10.7 0.0 4.0 82.4 15.8 0.0 146.7 1.3 26.7 0.0 0.0 69.2 0.0 0.1 4.8 1.2 0.0 18.0 0.7 17.2 9.2 79.5 80.8 0.2 0.1 2.8 172.1 89.9 27.5 2.5 3.7 5.9 0.1 33.1 108.0 4.6 0.0 0.0 5.5 0.1 0.1 0.1 0.4 0.2 6.5 2.5 0.4 0.0 1.1 0.1 0.0 2.5 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 3.7 7.9 0.0 0.3 17.4 18.4 48.9 18.1 14.8 16.9 18.1 18.7 18.6 16.6 17.0 15.7 11.2 3.2 57.7 13.4 1.4 13.6 39.2 79.6 26.7 0.8 27.3 19.4 211.3 67.2 76.2 136.1 0.0 0.8 11.8 74.9 29.4 65.5 0.1 62.5 6.6 20.9 45.5 5.3 0.1 68.1 20.3 11.3 143.2 74.9 10.2 0.1 48.2 183.6 12.3 5.0 0.5 50.8 69.2 16.3 4.6 1.7 18.0 6.3 3.6 2.8 4.1 15.9 0.0 5.0 0.2 41.2 153.8 22.2 1.2 44.6 61.0 73.5 45.4 1.5 144.7 4.7 64.0 0.5 5.0 14.8 11.2 25.3 2.4 1.5 48.5 63.1 GPX3 ENSG00000211445 "Glutathione peroxidase 3" P22352 5 151020438-151028992 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 11673.5" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 20125.9" "Cancer enhanced" "Detected in all" "renal cancer: 605.6;thyroid cancer: 856.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 20.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.7" "Cell line enriched" "Detected in many" 12 "ASC diff: 7677.4" "Region enhanced" "Detected in all" "hypothalamus: 239.5" "Low region specificity" "Detected in all" CAB069456 Approved "Secreted to blood" NA NA 5090000000 6200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB069456: AB_1616682" "unprognostic (4.03e-1)" "unprognostic (7.35e-2)" "unprognostic (5.05e-3)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "unprognostic (8.13e-2)" "unprognostic (1.39e-2)" "unprognostic (1.62e-1)" "unprognostic (5.75e-3)" "unprognostic (2.70e-3)" "unprognostic (8.17e-3)" "unprognostic (1.14e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (2.14e-1)" "unprognostic (5.11e-2)" "unprognostic (1.26e-1)" 4524.7 443.8 57.8 75.4 68.3 7.9 3188.6 62.7 73.8 917.6 578.2 741.2 88.3 416.0 90.7 568.6 1038.4 136.4 2362.4 68.2 117.5 11673.5 986.3 2471.8 133.2 317.7 104.5 517.8 257.0 112.4 793.7 592.2 136.6 557.5 93.4 4204.9 481.4 140.0 847.9 669.7 720.6 61.0 67.5 555.7 641.1 80.4 135.8 26.8 3627.5 458.9 44.9 1196.7 891.7 70.3 2.2 10.0 8.5 2.7 7677.4 6.7 9.2 3.5 0.8 7.9 2.4 177.5 3.9 1.1 214.1 5.6 3.2 2.8 39.6 433.2 6.0 6.1 2.5 1.9 4.3 195.0 294.7 0.5 4.3 649.1 41.2 0.2 1.0 10.6 11.3 1.2 1.2 0.3 11.0 31.4 0.5 1.2 13.8 0.8 0.2 1.0 5.2 1.7 74.1 4.3 11.3 11.4 1.2 31.6 1.9 33.6 43.5 2.1 2.5 2.3 19.6 3.7 1.0 2.7 15.6 2.5 7.0 3.0 0.6 0.0 4.3 0.1 0.0 1.6 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 20.7 0.0 0.2 0.0 0.0 1.6 57.8 68.3 62.7 73.8 68.2 117.5 317.7 104.5 136.6 67.5 135.8 70.3 353.6 9.6 33.7 1.0 106.8 18.5 86.9 94.8 1.2 26.3 31.7 5.5 639.8 18.6 58.3 649.2 43.8 713.8 2.2 2.3 1772.6 5.5 2.9 48.1 71.1 144.6 45.6 24.0 4.0 48.2 1191.3 514.0 50.0 627.9 11.4 274.9 735.3 228.4 151.5 16.8 0.4 5.9 91.6 47.9 86.7 17.5 446.7 160.2 23.2 3.7 0.7 5019.8 0.0 0.0 0.3 9.9 13.8 41.0 2.2 141.8 0.5 20125.9 39.1 86.8 683.7 131.6 264.6 7.1 10.3 13.9 21.6 1767.7 68.3 1.0 1.3 34.3 GPX4 "MCSP, PHGPx" ENSG00000167468 "Glutathione peroxidase 4" P36969 19 1103926-1106791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Oxidoreductase, Peroxidase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 18580.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008630, HPA047224, HPA058546" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "CAB008630: AB_1616685, HPA047224: AB_2679990, HPA058546: AB_2683749" "unprognostic (8.42e-3)" "prognostic favorable (7.18e-4)" "unprognostic (8.14e-3)" "prognostic favorable (1.84e-5)" "unprognostic (1.00e-1)" "unprognostic (8.72e-2)" "unprognostic (2.53e-3)" "unprognostic (8.49e-2)" "unprognostic (2.69e-2)" "unprognostic (1.47e-1)" "prognostic favorable (7.72e-4)" "unprognostic (1.29e-1)" "prognostic favorable (8.61e-4)" "unprognostic (1.61e-2)" "unprognostic (2.20e-1)" "unprognostic (6.67e-3)" "unprognostic (2.96e-2)" 927.8 535.3 415.1 127.4 428.7 178.0 733.3 440.7 519.1 280.8 478.7 249.0 259.0 188.4 318.9 220.4 199.2 196.6 426.0 419.2 450.3 536.5 687.8 307.9 216.4 430.9 448.3 260.3 157.9 285.5 398.4 147.2 454.1 322.1 110.9 167.5 304.9 193.8 672.3 290.4 236.2 87.9 418.2 213.2 219.0 1403.5 444.0 158.7 291.5 399.7 182.5 319.0 245.2 429.1 258.1 286.8 405.8 863.0 1202.1 706.0 449.3 199.3 713.5 371.1 375.9 590.5 339.8 92.8 211.8 405.8 313.5 283.1 239.7 289.3 180.5 522.3 436.5 175.0 246.9 849.2 697.4 207.6 269.4 707.3 432.1 188.3 314.7 665.9 527.1 317.5 249.4 225.7 311.1 660.4 353.8 354.9 386.2 569.7 458.9 482.8 55.3 271.3 408.9 629.9 348.3 220.6 390.5 366.1 422.1 246.7 358.1 498.0 450.9 392.3 257.4 680.6 254.6 786.5 582.0 224.3 369.4 412.2 230.9 578.9 539.6 564.4 219.8 405.4 256.9 352.7 319.7 230.7 404.0 309.9 339.4 245.0 265.1 196.6 462.2 278.8 310.3 841.7 415.1 428.7 440.7 519.1 419.2 450.3 430.9 448.3 454.1 418.2 444.0 429.1 415.9 179.5 189.7 21.2 281.7 510.0 525.8 1188.1 512.2 332.2 845.1 868.2 264.6 316.0 600.6 472.6 98.0 562.5 231.3 479.1 1592.6 515.8 4209.7 546.8 326.3 268.7 397.1 215.0 24.5 368.7 1327.3 536.1 99.9 442.3 346.1 242.6 322.0 826.2 1184.1 208.6 33.1 328.7 671.4 583.1 1304.8 18580.2 384.9 735.2 677.7 21.5 1786.8 502.6 192.6 13.6 35.4 484.0 507.9 312.9 189.2 694.7 1861.9 3024.7 800.9 246.0 243.3 244.6 587.1 1310.8 202.4 357.7 467.0 978.1 281.0 186.7 336.4 662.6 GPX5 ENSG00000224586 "Glutathione peroxidase 5" O75715 6 28525881-28534955 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "epididymis: 9.3" "Group enriched" "Detected in some" 46 "Early spermatids: 14.3;Late spermatids: 41.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.34e-2)" "unprognostic (3.74e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPX6 GPXP3 ENSG00000198704 "Glutathione peroxidase 6" P59796 6 28503296-28528215 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 15 "epididymis: 3.3" "Group enriched" "Detected in some" 6 "Early spermatids: 3.3;Late spermatids: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 16 "basal ganglia: 23.8" "Low region specificity" "Detected in single" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.99e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPX7 "FLJ14777, GPX6, NPGPx" ENSG00000116157 "Glutathione peroxidase 7" Q96SL4 1 52602371-52609051 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 68.6;HEL: 63.9;REH: 76.4;RPMI-8226: 130.0;THP-1: 101.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 25: RPMI-8226 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "unprognostic (7.43e-3)" "unprognostic (3.18e-1)" "unprognostic (5.64e-2)" "unprognostic (6.12e-3)" "unprognostic (1.73e-1)" "unprognostic (4.42e-2)" "unprognostic (8.18e-2)" "unprognostic (4.17e-1)" "unprognostic (2.48e-3)" "prognostic unfavorable (2.26e-5)" "unprognostic (1.14e-2)" "unprognostic (9.24e-2)" "unprognostic (3.08e-2)" "unprognostic (5.44e-2)" 8.4 7.9 4.8 12.4 5.0 18.3 11.9 5.2 5.4 11.6 9.3 9.4 3.3 13.1 7.3 4.3 9.1 13.4 10.8 4.6 5.9 6.9 5.3 6.8 16.5 5.2 5.1 8.9 11.5 8.5 12.5 29.3 5.0 8.7 5.5 1.7 5.9 9.7 12.1 5.0 6.0 10.8 5.0 8.1 5.0 5.5 5.0 15.9 17.1 11.5 14.0 12.4 6.9 4.9 0.1 0.0 18.1 33.9 6.6 19.1 0.1 12.5 0.7 14.8 15.3 12.2 0.0 0.1 9.8 68.6 0.0 0.0 29.0 0.0 8.1 0.0 0.2 63.9 3.6 11.3 23.9 0.0 0.0 44.4 0.0 2.5 0.0 0.0 22.9 0.4 0.0 0.0 28.2 0.0 3.3 33.5 31.5 0.0 0.0 76.4 0.0 130.0 1.3 0.0 13.7 27.0 33.3 0.0 21.9 3.0 0.0 101.1 1.4 0.0 3.7 3.8 0.1 0.1 0.0 47.9 0.0 0.2 11.3 0.2 1.7 5.4 22.6 0.4 31.8 32.0 34.6 27.1 5.4 35.2 44.5 29.0 0.9 31.6 0.2 73.7 27.6 21.4 4.8 5.0 5.2 5.4 4.6 5.9 5.2 5.1 5.0 5.0 5.0 4.9 8.4 3.2 5.5 1.0 16.1 2.2 9.0 8.3 1.2 1.0 7.1 13.6 3.9 12.8 6.5 3.7 0.0 22.8 9.2 0.2 5.9 11.1 6.9 8.2 43.7 12.4 1.2 6.7 1.6 15.6 19.8 30.5 0.5 6.5 1.3 25.8 15.4 3.8 12.3 5.0 2.7 1.2 2.0 1.9 0.7 6.6 15.2 6.0 7.2 4.7 5.0 8.3 9.2 4.5 2.0 4.7 0.7 13.5 25.2 5.7 0.0 3.0 7.0 0.6 13.1 13.3 14.5 10.8 12.1 1.9 3.3 15.6 10.9 19.3 0.6 4.9 GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 62.7;Extravillous trophoblasts: 218.9;Fibroblasts: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 254.4;fHDF/TERT166: 246.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: AB_2675269" "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (5.13e-9)" "prognostic unfavorable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" 13.3 6.1 1.2 12.5 1.2 0.1 12.6 1.2 1.6 37.1 6.9 7.3 2.9 21.1 21.9 6.2 14.3 17.0 11.2 1.0 1.7 6.5 2.2 6.9 3.8 1.5 1.1 27.3 4.6 9.3 2.4 39.7 1.4 10.2 8.4 1.3 7.2 15.8 1.5 5.0 4.1 27.2 1.5 4.0 5.6 5.6 1.2 1.3 22.3 6.3 3.0 17.8 9.8 3.6 37.2 39.0 75.3 77.0 180.7 223.9 36.6 179.8 254.4 97.0 192.7 3.2 82.1 0.0 199.0 246.4 86.5 28.2 46.0 51.5 131.5 0.5 17.3 2.1 49.1 6.9 64.4 0.0 0.0 157.5 60.8 68.3 35.5 126.5 122.7 0.0 1.1 0.1 137.4 14.4 0.0 0.0 32.6 1.0 42.8 0.1 40.2 0.0 65.9 1.3 0.1 1.4 56.6 4.6 68.0 80.8 56.6 3.4 102.7 63.6 65.6 84.5 102.3 0.1 0.5 0.5 103.0 0.1 118.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 1.6 1.0 1.7 1.5 1.1 1.4 1.5 1.2 3.6 10.9 0.0 1.1 0.3 0.3 7.1 6.0 38.3 9.1 0.2 8.9 6.1 4.3 0.0 33.3 25.8 0.0 49.5 0.2 0.5 5.9 13.7 0.4 6.5 62.7 18.6 0.0 0.0 0.1 38.8 218.9 76.6 2.6 4.9 4.5 30.9 19.2 0.2 10.2 0.0 0.1 4.7 4.1 0.0 6.9 0.6 51.3 1.1 24.9 5.6 1.1 7.9 0.0 0.0 0.1 15.8 0.3 39.9 1.4 2.6 0.1 0.5 36.5 0.3 13.1 20.1 38.2 0.1 0.4 3.1 6.1 13.3 1.8 29.9 0.9 2.4 GRAMD1C DKFZp434C0328 ENSG00000178075 "GRAM domain containing 1C" Q8IYS0 3 113828182-113947174 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 181.8;Early spermatids: 97.1;Late spermatids: 80.5;Oligodendrocyte precursor cells: 82.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "memory B-cell: 2.7;naive B-cell: 2.9;neutrophil: 2.1" "Group enriched" "Detected in many" 13 "B-cells: 2.9;granulocytes: 2.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.5;HUVEC TERT2: 10.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA012316 Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" "HPA012316: AB_1849949" "unprognostic (2.73e-3)" "unprognostic (6.16e-3)" "unprognostic (3.27e-1)" "unprognostic (1.93e-1)" "unprognostic (5.50e-2)" "unprognostic (9.81e-3)" "unprognostic (1.43e-3)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (1.85e-1)" "unprognostic (5.49e-2)" "prognostic favorable (4.22e-15)" "unprognostic (8.48e-2)" "unprognostic (9.96e-2)" "unprognostic (3.61e-2)" "unprognostic (2.09e-2)" 1.4 1.9 13.0 1.7 12.0 0.1 8.8 11.9 15.3 3.1 9.0 5.0 7.6 2.2 2.0 5.5 10.7 2.6 0.7 11.6 12.1 24.0 27.7 4.9 2.0 13.9 15.4 0.8 12.7 10.6 8.1 6.1 11.8 2.6 3.9 14.3 12.0 2.1 0.8 12.1 16.7 0.7 12.3 1.3 9.0 16.8 14.5 1.1 3.9 3.2 3.9 2.0 3.7 10.0 1.6 0.0 4.0 3.0 0.7 1.8 5.2 3.5 3.1 0.7 2.1 0.0 13.5 0.4 1.0 2.0 1.4 1.3 0.7 1.5 1.8 1.9 0.6 0.3 0.1 0.0 1.4 0.2 0.0 3.0 1.0 0.6 0.1 7.1 10.2 4.5 0.0 0.1 1.1 0.4 1.6 0.2 0.3 1.4 0.5 0.0 0.8 2.4 4.2 1.9 0.8 1.1 1.0 5.2 3.4 1.6 3.6 0.0 2.2 1.5 2.8 0.0 0.3 2.2 1.3 1.9 2.2 0.1 1.8 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.1 0.2 0.0 2.9 0.1 0.1 2.1 0.1 0.0 0.0 0.0 0.0 13.0 12.0 11.9 15.3 11.6 12.1 13.9 15.4 11.8 12.3 14.5 10.0 4.5 12.8 10.5 181.8 15.6 1.0 6.9 3.0 5.2 0.2 9.9 7.0 0.9 15.7 7.1 14.7 37.5 17.5 0.3 10.1 31.3 4.4 97.1 33.3 8.5 4.7 4.9 2.7 29.7 2.7 3.7 1.5 6.6 51.9 0.0 1.4 5.7 17.0 1.5 11.8 4.3 5.5 4.1 0.3 0.8 80.5 2.8 0.9 1.8 9.4 0.1 13.4 0.0 82.4 1.7 2.3 9.3 1.5 6.3 2.8 34.3 14.0 27.9 19.7 0.0 1.2 1.7 28.2 6.7 6.8 4.7 42.4 1.9 5.0 5.3 7.0 GREM1 "CKTSF1B1, CRAC1, DAND2, DRM, gremlin, HMPS" ENSG00000166923 "Gremlin 1, DAN family BMP antagonist" O60565 15 32718004-32745106 "Disease related genes, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 113.0;smooth muscle: 68.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 66.2;Granulosa cells: 121.1;Oligodendrocytes: 40.5;Skeletal myocytes: 181.4" "Cancer enhanced" "Detected in many" "stomach cancer: 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 294.7;BJ hTERT+: 468.5;BJ hTERT+ SV40 Large T+ RasG12V: 286.8;fHDF/TERT166: 957.0;hTEC/SVTERT24-B: 227.8" "Group enriched" "Detected in many" 5 "hippocampal formation: 3.2;olfactory bulb: 10.9" "Low region specificity" "Detected in many" HPA007526 Uncertain "Secreted to blood" NA NA 242000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA007526: AB_1849971" "unprognostic (4.74e-2)" "unprognostic (2.78e-1)" "unprognostic (4.63e-2)" "unprognostic (6.80e-2)" "unprognostic (3.58e-1)" "unprognostic (1.72e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (5.33e-2)" "unprognostic (2.32e-1)" "unprognostic (7.20e-3)" "unprognostic (2.79e-1)" "unprognostic (2.13e-11)" "unprognostic (1.77e-2)" "unprognostic (6.60e-2)" "unprognostic (3.29e-2)" "unprognostic (1.16e-3)" 32.7 0.5 1.4 6.5 3.6 0.2 5.5 1.1 2.4 44.7 0.0 36.1 2.6 9.6 0.0 13.6 1.1 113.0 1.3 1.5 1.3 1.2 1.1 2.2 1.1 3.1 3.0 0.3 2.2 0.0 0.2 0.3 1.8 8.2 26.7 0.1 0.6 3.8 0.6 7.6 52.3 68.2 1.1 0.8 36.8 0.5 3.8 0.0 2.3 0.0 1.7 21.7 50.4 6.1 0.0 3.5 0.0 0.0 11.1 12.5 0.0 294.7 468.5 112.5 286.8 0.3 0.0 0.0 0.0 957.0 0.0 0.0 0.0 0.0 109.7 0.0 0.1 0.0 0.1 0.0 3.3 0.0 0.0 3.1 0.0 227.8 0.1 70.6 0.0 0.0 0.0 0.0 143.4 0.1 0.0 0.0 1.2 0.0 0.9 0.0 20.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.0 57.7 0.0 0.1 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 3.6 1.1 2.4 1.5 1.3 3.1 3.0 1.8 1.1 3.8 6.1 0.7 0.0 0.0 0.3 0.4 6.6 6.5 0.0 0.6 2.1 1.7 0.9 3.4 0.0 0.0 66.2 2.1 0.2 0.7 0.4 0.0 0.4 0.2 0.6 2.3 1.9 0.0 0.0 2.5 0.0 0.1 17.7 0.0 0.7 0.0 121.1 0.7 1.2 1.0 1.7 0.5 0.6 0.0 0.3 12.8 0.0 0.0 2.3 3.6 0.0 2.7 0.3 0.0 1.5 40.5 0.3 0.0 0.4 0.2 9.9 0.1 0.3 0.0 1.3 0.0 181.4 16.1 0.1 1.4 0.3 4.5 0.3 2.1 0.1 0.1 6.5 GREM2 "CKTSF1B2, DAND3, FLJ21195, Prdc" ENSG00000180875 "Gremlin 2, DAN family BMP antagonist" Q9H772 1 240489573-240612155 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Heparin-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 31.4;liver: 26.3" "Cell type enriched" "Detected in many" 9 "Syncytiotrophoblasts: 298.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 32.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB009920 Approved "Secreted to blood" NA NA 12000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB009920: AB_2279266" "unprognostic (2.01e-1)" "unprognostic (2.49e-1)" "unprognostic (7.41e-2)" "unprognostic (7.58e-3)" "unprognostic (2.82e-3)" "unprognostic (1.34e-1)" "unprognostic (8.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.31e-2)" "unprognostic (6.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.97e-2)" "unprognostic (3.07e-8)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.38e-2)" 0.8 1.7 2.1 9.7 2.9 0.1 3.4 0.1 6.1 0.9 0.0 17.1 10.8 9.6 2.2 17.1 1.4 31.4 0.0 1.3 1.8 2.3 26.3 1.2 0.2 2.1 1.7 6.6 0.2 22.9 2.1 4.0 1.9 2.6 20.1 5.8 4.2 1.8 7.3 3.6 14.9 6.4 1.3 3.2 9.3 0.3 2.8 0.3 0.5 0.7 0.2 3.8 0.5 2.0 0.0 0.0 0.1 0.0 1.9 2.4 0.0 6.1 6.5 0.0 0.0 0.0 0.0 0.0 0.0 32.3 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 2.2 0.0 2.8 1.3 0.0 0.0 3.9 0.5 0.8 0.4 1.0 0.0 0.0 3.3 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 2.9 0.1 6.1 1.3 1.8 2.1 1.7 1.9 1.3 2.8 2.0 0.2 0.0 0.0 0.3 0.2 4.7 0.0 0.0 0.6 20.8 14.0 0.1 0.6 0.0 0.0 0.0 12.5 7.4 0.6 0.6 0.0 0.0 0.0 2.3 1.2 0.6 1.2 0.0 28.6 0.0 1.7 17.4 0.0 13.7 0.0 0.1 0.7 20.4 1.5 0.0 30.5 0.1 0.0 0.3 6.2 0.2 0.0 0.2 1.8 3.7 0.0 0.4 1.0 1.5 1.2 0.1 0.1 4.5 0.1 0.6 0.0 0.0 0.7 6.7 0.0 0.2 1.4 2.4 2.7 0.6 3.7 298.0 1.6 2.3 0.6 0.1 GRIA2 "GluA2, GLUR2, GLURB" ENSG00000120251 "Glutamate ionotropic receptor AMPA type subunit 2" P42262 4 157204182-157366075 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Autism spectrum disorder, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;retina: 29.0" "Cell type enhanced" "Detected in some" "Astrocytes: 335.0;Bipolar cells: 252.7;Excitatory neurons: 1090.5;Inhibitory neurons: 725.5;Oligodendrocyte precursor cells: 1106.8;Oligodendrocytes: 324.7" "Group enriched" "Detected in some" 10 "breast cancer: 2.7;endometrial cancer: 2.6;glioma: 6.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 16.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008441 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA008441: AB_1078983" "unprognostic (1.36e-1)" "unprognostic (9.60e-3)" "unprognostic (4.15e-2)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (8.70e-2)" "unprognostic (3.87e-1)" "unprognostic (1.53e-1)" "unprognostic (3.92e-3)" "unprognostic (7.40e-2)" "unprognostic (2.91e-5)" "unprognostic (2.42e-1)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" "unprognostic (6.55e-2)" 0.3 6.9 32.8 0.2 60.2 0.0 1.1 11.4 77.4 9.2 0.0 0.2 0.1 17.0 11.5 0.1 11.0 0.0 0.1 78.4 11.3 0.4 0.0 0.2 0.0 0.0 7.4 0.6 1.4 0.0 21.7 0.1 0.0 0.8 0.1 29.0 4.1 2.3 0.2 1.6 0.1 6.2 1.4 0.2 1.2 1.4 37.3 0.1 0.0 0.6 0.0 0.1 0.4 43.2 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 2.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.9 0.1 0.0 0.0 0.5 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 60.2 11.4 77.4 78.4 11.3 0.0 7.4 0.0 1.4 37.3 43.2 0.0 0.0 0.0 335.0 0.0 0.0 0.0 0.0 0.0 252.7 2.1 1.0 2.3 0.0 0.0 0.0 43.8 0.0 0.1 0.0 0.0 0.0 0.1 1.7 1.1 0.3 0.0 0.0 1090.5 0.0 0.0 0.2 0.0 2.7 0.0 0.1 0.0 0.0 0.1 138.0 725.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 58.1 0.0 4.2 0.0 1106.8 324.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.5 3.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 GRIA3 "GluA3, GLUR3, GLURC, MRX94" ENSG00000125675 "Glutamate ionotropic receptor AMPA type subunit 3" P42263 X 123184153-123490915 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.6;retina: 17.8" "Group enriched" "Detected in some" 5 "Excitatory neurons: 468.4;Horizontal cells: 198.5;Inhibitory neurons: 396.3;Oligodendrocyte precursor cells: 385.0" "Cancer enriched" "Detected in some" 11 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 23.8;BJ hTERT+: 34.5;fHDF/TERT166: 45.9;U-2197: 15.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058659, HPA073344" Enhanced "Intracellular and membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA058659: AB_2683791, HPA073344: " "unprognostic (2.14e-2)" "unprognostic (6.00e-2)" "unprognostic (2.02e-2)" "unprognostic (2.94e-3)" "unprognostic (5.09e-2)" "unprognostic (4.29e-4)" "unprognostic (2.42e-1)" "unprognostic (6.74e-2)" "unprognostic (1.44e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-3)" "unprognostic (1.31e-1)" "unprognostic (3.78e-3)" "unprognostic (8.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" 0.8 10.3 20.0 0.3 25.3 0.1 1.4 1.3 31.6 6.7 0.0 0.7 0.3 2.1 3.6 0.4 1.5 1.2 2.0 29.0 4.0 2.5 7.7 0.3 0.5 1.9 3.4 4.1 1.7 0.0 1.0 0.4 1.4 1.7 0.8 17.8 0.2 1.9 0.2 0.5 0.5 1.9 4.5 0.1 2.0 0.7 6.4 0.2 0.2 0.1 0.8 0.6 2.8 20.9 0.0 0.0 0.0 0.0 2.2 0.4 0.0 23.8 34.5 0.4 0.9 0.0 0.0 0.0 0.0 45.9 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 6.6 0.0 15.1 0.2 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 25.3 1.3 31.6 29.0 4.0 1.9 3.4 1.4 4.5 6.4 20.9 0.1 0.0 0.0 27.4 0.0 0.3 0.0 0.8 0.6 13.6 0.2 0.0 1.6 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.1 0.3 8.7 0.3 0.0 0.0 468.4 0.2 0.1 6.4 1.1 0.2 0.0 0.1 0.4 6.1 0.1 198.5 396.3 0.0 0.0 0.0 1.5 0.3 9.3 0.2 1.8 14.0 0.0 1.9 0.0 385.0 67.6 0.3 0.0 4.1 0.0 0.4 0.0 6.2 0.1 3.8 0.0 0.2 4.5 0.0 0.1 0.0 1.0 0.1 0.1 0.7 0.0 0.0 GRIA4 "GluA4, GLUR4, GLURD" ENSG00000152578 "Glutamate ionotropic receptor AMPA type subunit 4" P48058 11 105609994-105982092 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 105.5;retina: 32.1" "Group enriched" "Detected in some" 5 "Excitatory neurons: 799.1;Horizontal cells: 471.1;Inhibitory neurons: 1045.0;Oligodendrocyte precursor cells: 755.5" "Cancer enriched" "Detected in some" 5 "glioma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 12.1;NTERA-2: 4.0;RPMI-8226: 2.4;SCLC-21H: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.45e-1)" "unprognostic (2.63e-1)" "unprognostic (4.09e-4)" "unprognostic (4.45e-3)" "unprognostic (1.92e-3)" "unprognostic (4.14e-4)" "unprognostic (1.40e-2)" "unprognostic (3.73e-4)" "unprognostic (1.62e-1)" "unprognostic (3.89e-1)" "unprognostic (2.04e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (2.48e-1)" "unprognostic (1.38e-1)" "unprognostic (3.35e-2)" "unprognostic (1.28e-1)" 0.1 5.6 5.3 0.5 20.7 0.0 3.1 105.5 32.2 1.4 0.0 1.5 0.0 0.5 1.6 0.0 1.0 0.2 0.1 27.7 21.4 0.5 0.0 0.0 0.6 30.5 24.2 0.2 0.8 0.0 2.3 0.3 36.7 0.2 0.9 32.1 3.0 0.4 0.1 0.5 3.2 0.0 21.0 0.0 5.7 0.1 18.9 0.0 0.1 0.0 0.4 0.0 0.1 19.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 4.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 20.7 105.5 32.2 27.7 21.4 30.5 24.2 36.7 21.0 18.9 19.0 0.0 0.0 0.0 36.9 0.0 0.1 0.0 0.0 0.0 48.2 0.9 7.4 1.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.2 0.8 0.0 2.2 0.4 0.0 0.0 799.1 0.0 0.0 1.2 0.5 0.1 0.0 0.0 0.0 0.0 1.1 471.1 1045.0 3.7 0.0 0.0 0.4 0.2 0.6 0.0 0.0 100.2 0.0 20.4 0.0 755.5 129.9 0.0 0.0 0.0 0.0 0.0 9.1 0.9 0.0 8.9 0.0 1.6 0.2 0.0 0.3 0.0 0.1 0.3 0.1 0.0 5.2 0.0 GRIK2 "GluK2, GLUR6, MRT6" ENSG00000164418 "Glutamate ionotropic receptor kainate type subunit 2" Q13002 6 101181257-102070083 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "brain: 93.3" "Group enriched" "Detected in some" 26 "Excitatory neurons: 724.6;Inhibitory neurons: 2376.0;Oligodendrocyte precursor cells: 1234.0" "Cancer enriched" "Detected in some" 5 "glioma: 3.9" "Region enhanced" "Detected in all" "cerebellum: 93.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 16.4;BJ hTERT+: 26.6;fHDF/TERT166: 20.8;HAP1: 10.2;SiHa: 11.1;WM-115: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014395, HPA014623, CAB022463" Approved "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022463: , HPA014395: AB_1850303, HPA014623: AB_1850305" "unprognostic (1.43e-3)" "unprognostic (1.26e-2)" "unprognostic (3.99e-2)" "unprognostic (3.20e-1)" "unprognostic (1.92e-1)" "unprognostic (3.48e-2)" "unprognostic (2.57e-1)" "unprognostic (4.32e-2)" "unprognostic (8.46e-2)" "unprognostic (9.19e-2)" "unprognostic (4.01e-2)" "unprognostic (1.36e-1)" "unprognostic (1.34e-5)" "unprognostic (1.94e-3)" "unprognostic (7.78e-2)" "unprognostic (1.09e-2)" "unprognostic (8.68e-4)" 0.2 1.8 18.7 0.4 20.3 0.3 0.2 93.3 25.2 1.4 0.0 0.5 0.6 0.4 1.1 0.4 0.3 0.5 4.5 20.7 28.4 0.8 0.1 0.1 0.1 1.0 6.8 0.4 2.6 0.0 1.6 2.4 7.9 0.9 0.4 4.2 0.7 1.2 0.9 1.6 0.6 0.3 1.6 0.4 0.3 0.7 19.8 0.0 3.4 0.1 0.0 0.5 0.4 7.6 0.1 0.1 3.1 0.2 3.6 0.1 0.0 16.4 26.6 0.8 0.5 0.0 0.3 0.1 0.0 20.8 0.0 5.1 10.2 0.0 0.3 0.0 0.0 1.7 8.5 0.0 0.9 0.0 0.2 0.3 0.0 0.0 1.0 2.3 0.0 0.0 0.0 0.4 6.2 0.0 0.0 0.2 2.7 0.0 0.2 0.1 0.4 0.1 0.7 0.0 3.3 7.0 11.1 0.0 0.5 0.5 0.0 0.8 0.0 2.1 0.5 0.1 1.3 0.1 0.0 0.1 1.5 0.0 24.6 0.5 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.0 0.0 18.7 20.3 93.3 25.2 20.7 28.4 1.0 6.8 7.9 1.6 19.8 7.6 0.2 0.0 0.5 54.9 0.0 0.6 1.0 0.1 0.6 11.4 0.1 0.0 5.9 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 3.8 3.4 1.9 0.4 1.8 0.0 724.6 0.6 0.0 1.8 0.0 0.5 0.0 13.0 0.0 0.0 0.1 0.0 2376.0 0.0 0.0 0.0 0.0 7.7 0.3 0.1 1.8 38.4 0.0 0.5 0.0 1234.0 40.5 0.1 1.1 0.4 0.0 0.8 0.1 0.0 2.2 1.1 0.0 0.7 4.6 0.0 0.5 0.1 0.6 0.0 0.0 4.3 0.1 0.9 GRIN2A "GluN2A, NMDAR2A" ENSG00000183454 "Glutamate ionotropic receptor NMDA type subunit 2A" Q12879 16 9753404-10182928 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 31.7" "Group enriched" "Detected in some" 13 "Excitatory neurons: 839.8;Inhibitory neurons: 904.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 31.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;fHDF/TERT166: 4.4;hTERT-RPE1: 1.4;RPMI-8226: 1.8;U-138 MG: 4.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022725 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022725: " "unprognostic (6.43e-2)" "unprognostic (2.47e-1)" "unprognostic (5.97e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-2)" "unprognostic (1.59e-2)" "unprognostic (1.62e-1)" "unprognostic (2.10e-1)" "unprognostic (2.08e-1)" "unprognostic (5.39e-2)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (3.75e-3)" "unprognostic (4.79e-3)" "unprognostic (2.05e-1)" "unprognostic (3.92e-3)" "unprognostic (3.33e-2)" 0.3 0.3 4.7 0.0 8.4 0.0 0.1 0.0 31.7 0.3 0.0 0.2 0.3 0.3 2.5 1.1 2.1 0.1 3.0 20.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.2 2.2 0.2 0.3 0.0 0.5 0.2 0.4 0.0 0.0 0.4 2.1 0.1 0.6 0.2 0.2 0.2 0.1 0.4 10.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.3 1.1 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 8.4 0.0 31.7 20.0 0.0 0.0 0.0 0.0 0.0 0.1 10.3 0.2 0.0 0.0 16.0 0.0 1.9 2.2 0.5 3.4 10.3 0.3 0.0 18.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 2.1 17.2 0.3 0.1 0.5 0.0 0.0 839.8 0.2 0.0 2.7 0.0 0.7 0.0 3.3 0.0 0.3 0.1 1.7 904.7 0.0 0.0 0.3 0.4 15.1 0.9 0.1 0.0 15.9 0.0 15.6 0.0 27.6 65.8 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 13.9 0.0 0.0 5.4 8.2 10.0 0.2 0.4 0.0 0.0 0.0 0.1 0.3 GRIN2B "GluN2B, NMDAR2B" ENSG00000273079 "Glutamate ionotropic receptor NMDA type subunit 2B" Q13224 12 13437942-13982002 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "brain: 36.1" "Group enriched" "Detected in some" 4 "Excitatory neurons: 625.2;Inhibitory neurons: 882.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 34 "amygdala: 11.5;basal ganglia: 15.6;cerebral cortex: 36.1;hippocampal formation: 29.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.3;NTERA-2: 1.6;RPTEC TERT1: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069762 Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA069762: AB_2686192" "unprognostic (2.01e-2)" "unprognostic (4.07e-2)" "unprognostic (7.89e-2)" "unprognostic (3.77e-3)" "unprognostic (3.39e-3)" "unprognostic (9.36e-2)" "unprognostic (5.92e-2)" "unprognostic (1.77e-2)" "unprognostic (6.85e-2)" "unprognostic (2.24e-1)" "unprognostic (4.68e-2)" "unprognostic (4.12e-2)" "unprognostic (4.48e-5)" "unprognostic (2.43e-1)" "unprognostic (8.76e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-1)" 0.2 0.0 11.5 0.0 15.6 0.0 0.0 0.0 36.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.6 0.0 36.1 29.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 8.8 0.7 0.5 3.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.9 0.0 35.0 0.3 0.1 0.4 0.0 0.0 625.2 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 882.5 0.5 0.0 0.0 0.0 35.8 0.0 0.0 0.0 14.0 0.0 0.1 0.0 173.4 9.9 0.0 0.1 0.4 0.0 0.2 0.0 0.1 0.0 1.8 0.0 0.1 0.2 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 GRM2 "GPRC1B, mGlu2, MGLUR2" ENSG00000164082 "Glutamate metabotropic receptor 2" Q14416 3 51707068-51718613 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "brain: 6.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.6;Cone photoreceptor cells: 6.2;Excitatory neurons: 16.2;Spermatocytes: 3.5" "Cancer enriched" "Detected in single" 4 "testis cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027868, HPA065166" Approved Supported NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA027868: , HPA065166: AB_2685425" "unprognostic (1.01e-1)" "unprognostic (8.61e-4)" "unprognostic (7.66e-2)" "unprognostic (7.29e-3)" "unprognostic (1.98e-1)" "unprognostic (3.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.27e-1)" "unprognostic (1.39e-2)" "unprognostic (2.05e-1)" "unprognostic (4.45e-1)" "unprognostic (1.74e-1)" "unprognostic (1.37e-2)" "unprognostic (1.35e-1)" "unprognostic (1.82e-1)" "unprognostic (2.93e-2)" "unprognostic (1.19e-2)" 0.3 0.0 1.6 0.0 2.2 0.4 0.1 0.0 2.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.7 0.7 0.0 0.0 0.1 0.0 4.9 0.1 0.0 0.1 0.0 0.1 0.0 6.0 0.1 0.0 0.4 0.1 0.0 0.3 0.5 0.1 0.0 0.0 0.2 0.0 0.6 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.2 0.0 2.3 1.7 0.7 4.9 0.1 6.0 0.0 0.4 0.3 0.4 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 2.6 0.5 0.9 1.1 0.0 0.0 0.0 6.2 0.0 0.3 0.1 0.0 0.0 0.3 0.1 0.1 1.5 0.0 0.0 16.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.4 0.0 1.0 0.8 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.0 2.0 0.0 0.2 0.1 3.5 1.1 0.2 0.3 0.0 0.1 0.2 0.0 0.1 GRM3 "GPRC1C, mGlu3, MGLUR3" ENSG00000198822 "Glutamate metabotropic receptor 3" Q14832 7 86643914-86864884 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 79.3" "Group enriched" "Detected in some" 20 "Astrocytes: 410.7;Excitatory neurons: 272.0;Oligodendrocytes: 1028.4" "Cancer enriched" "Detected in single" 7 "glioma: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "AF22: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (2.05e-1)" "unprognostic (3.78e-2)" "unprognostic (1.90e-1)" "unprognostic (2.70e-3)" "unprognostic (3.16e-1)" "unprognostic (1.07e-3)" "unprognostic (6.99e-3)" "unprognostic (2.98e-1)" "unprognostic (2.71e-1)" "unprognostic (9.13e-3)" "unprognostic (1.88e-3)" "unprognostic (2.04e-1)" "unprognostic (3.91e-3)" "unprognostic (4.00e-2)" "unprognostic (9.34e-2)" "unprognostic (1.72e-3)" "unprognostic (1.12e-2)" 0.1 0.8 29.2 0.0 48.8 0.0 0.1 36.5 40.8 0.1 5.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 35.5 28.7 0.1 0.0 0.1 0.0 38.8 36.3 0.0 0.0 0.0 0.4 0.0 36.1 0.4 0.0 1.8 0.1 0.1 0.8 0.0 0.0 0.0 29.5 0.5 0.1 0.7 36.6 0.1 0.1 0.0 0.0 0.1 0.0 79.3 0.0 0.0 35.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 48.8 36.5 40.8 35.5 28.7 38.8 36.3 36.1 29.5 36.6 79.3 1.2 0.0 0.0 410.7 0.1 0.1 0.6 0.5 0.0 6.7 0.2 0.3 1.2 0.0 0.2 0.0 4.2 0.0 0.2 0.1 0.0 0.0 21.8 0.1 0.1 0.7 0.0 0.0 272.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 13.5 16.5 0.0 2.0 0.0 0.0 2.7 0.3 0.0 1.8 28.1 0.0 0.2 0.0 20.1 1028.4 0.1 0.1 0.4 0.0 0.5 0.0 0.0 0.1 2.2 0.0 1.0 0.3 1.3 0.2 0.0 0.0 0.0 0.2 0.3 0.1 0.4 GRM5 "GPRC1E, mGlu5, MGLUR5, PPP1R86" ENSG00000168959 "Glutamate metabotropic receptor 5" P41594 11 88504576-89065945 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 23.8" "Group enriched" "Detected in some" 26 "Excitatory neurons: 903.1;Inhibitory neurons: 968.3;Oligodendrocyte precursor cells: 1040.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "amygdala: 14.9;basal ganglia: 17.3;cerebral cortex: 23.8;hippocampal formation: 20.4;white matter: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 10: Brain - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (9.57e-2)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (2.62e-1)" "unprognostic (1.26e-1)" "unprognostic (7.16e-2)" "unprognostic (8.15e-4)" "unprognostic (3.43e-2)" 0.0 0.0 14.9 0.0 17.3 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 20.4 1.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.3 0.0 0.0 2.8 0.0 0.0 1.7 3.7 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 17.3 0.0 23.8 20.4 1.0 0.0 0.0 0.0 2.8 3.7 6.4 0.1 0.0 0.0 36.6 0.0 0.0 0.0 0.0 0.0 28.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 7.5 0.1 0.0 0.0 0.0 903.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.7 968.3 0.0 0.0 0.0 0.0 23.6 0.3 0.0 0.0 22.5 0.0 0.8 0.0 1040.5 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 1.8 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 GRM8 "GLUR8, GPRC1H, mGlu8, MGLUR8" ENSG00000179603 "Glutamate metabotropic receptor 8" O00222 7 126438598-127253093 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 44.3" "Cell type enhanced" "Detected in some" "Early spermatids: 59.5;Excitatory neurons: 104.9;Inhibitory neurons: 134.0;Late spermatids: 69.1;Oligodendrocyte precursor cells: 32.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.9;HEK 293: 1.4;NTERA-2: 3.5;RH-30: 2.4;SCLC-21H: 3.3;SH-SY5Y: 1.7;U-2 OS: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051481 Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA051481: AB_2681499" "unprognostic (4.57e-3)" "unprognostic (5.10e-4)" "unprognostic (1.21e-1)" "unprognostic (2.09e-2)" "unprognostic (1.83e-1)" "unprognostic (5.54e-2)" "unprognostic (2.06e-4)" "unprognostic (1.79e-1)" "unprognostic (8.90e-2)" "unprognostic (1.31e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-1)" "unprognostic (3.12e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (1.32e-2)" "unprognostic (1.12e-2)" 0.0 0.6 3.0 0.3 3.3 0.0 0.0 0.7 3.7 0.1 44.3 1.7 0.1 0.0 0.0 0.0 0.1 0.5 2.4 4.5 4.7 0.6 3.6 0.2 0.0 8.1 8.4 0.8 0.5 0.0 0.3 0.0 9.0 0.1 2.0 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.7 2.7 0.0 0.9 0.0 0.1 0.5 0.0 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.0 2.4 0.0 0.1 0.0 3.3 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 1.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.3 0.7 3.7 4.5 4.7 8.1 8.4 9.0 0.0 2.7 1.8 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 1.1 1.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 59.5 0.0 0.0 0.6 1.2 0.0 104.9 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 1.2 0.0 0.0 134.0 0.7 0.0 0.0 0.0 69.1 0.6 0.0 0.0 13.1 0.0 0.3 0.0 32.6 9.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 1.2 1.6 0.0 0.0 0.0 0.0 0.1 0.9 0.0 GRN "CLN11, PCDGF, PGRN" ENSG00000030582 "Granulin precursor" P28799 17 44345246-44353106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 1420.7;Kupffer cells: 892.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 2057.5;intermediate monocyte: 1122.4;myeloid DC: 1534.2;neutrophil: 851.2;non-classical monocyte: 548.1;plasmacytoid DC: 1331.9" "Group enriched" "Detected in all" 9 "dendritic cells: 1534.2;granulocytes: 851.2;monocytes: 2057.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008763, CAB019394, HPA028747" Uncertain Enhanced Endosomes,Lysosomes "Secreted to blood" NA NA 138000000 110000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Lysosomes Endosomes "CAB019394: , HPA008763: AB_1850339, HPA028747: AB_10603767" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "unprognostic (8.38e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (7.41e-2)" "unprognostic (3.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.52e-1)" "unprognostic (6.34e-2)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" 158.9 123.2 61.5 160.4 67.2 478.5 120.7 67.7 97.3 156.7 73.9 189.8 130.9 108.3 134.0 534.0 87.1 157.3 153.0 61.0 69.7 167.4 118.9 309.5 183.2 81.0 71.5 73.8 108.9 87.8 84.4 183.2 87.6 111.7 110.3 12.5 262.9 100.6 60.6 189.7 179.0 91.9 71.8 349.8 127.9 59.4 94.3 67.8 127.7 45.9 107.8 150.0 198.3 97.3 119.3 197.5 52.7 159.5 443.2 231.8 181.2 147.3 447.5 231.6 309.8 86.3 294.0 364.0 299.4 217.6 312.9 185.3 68.6 334.5 75.8 55.8 186.8 38.4 93.8 175.2 245.5 61.6 493.6 332.4 450.5 188.1 106.0 391.2 269.8 64.3 75.1 51.3 148.8 183.1 32.8 172.8 44.3 110.5 334.0 97.7 180.8 433.0 248.2 145.9 54.7 74.7 201.0 92.7 360.9 138.0 209.4 229.0 340.7 437.6 104.6 300.5 97.8 116.3 313.9 122.3 268.1 149.6 124.2 215.1 2057.5 176.5 35.1 1122.4 27.8 174.0 37.1 31.1 1534.2 112.2 27.8 26.5 851.2 30.6 548.1 1331.9 55.4 1613.4 61.5 67.2 67.7 97.3 61.0 69.7 81.0 71.5 87.6 71.8 94.3 97.3 113.0 86.6 83.3 12.7 82.8 112.7 151.1 574.2 97.9 23.6 85.7 69.7 90.7 133.0 332.7 218.8 18.8 429.1 195.7 494.8 9.8 447.7 2.1 103.8 83.8 170.9 124.3 38.7 6.8 307.3 324.1 149.4 83.6 372.5 75.5 90.0 207.8 84.7 1420.7 47.1 6.6 214.6 146.5 892.0 360.8 6.8 60.9 699.2 208.1 20.6 501.6 58.9 20.6 11.1 11.8 285.3 581.7 57.2 65.8 70.7 312.1 120.5 70.0 11.8 85.5 45.4 83.3 25.1 72.2 255.5 96.5 640.0 30.8 89.6 274.5 175.6 GRP ENSG00000134443 "Gastrin releasing peptide" P07492 18 59220158-59230774 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;stomach 1: 12.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 24.4;Early spermatids: 15.5;Ionocytes: 6.1;Late spermatids: 12.2;Sertoli cells: 6.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.6" "Region enriched" "Detected in all" 4 "midbrain: 26.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BJ hTERT+: 5.1;fHDF/TERT166: 6.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 24.9" "Secreted in other tissues" NA NA 340000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.91e-2)" "unprognostic (1.85e-1)" "unprognostic (2.30e-3)" "unprognostic (3.21e-2)" "unprognostic (7.86e-3)" "unprognostic (3.01e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-1)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (1.79e-1)" "unprognostic (5.86e-4)" "unprognostic (2.65e-4)" "unprognostic (9.94e-2)" "unprognostic (6.99e-2)" "unprognostic (5.16e-2)" 0.3 0.2 3.2 0.2 2.6 0.0 2.6 1.3 5.0 0.1 2.8 2.1 0.1 0.3 0.3 0.0 0.0 0.3 0.0 6.1 6.0 0.4 0.0 9.0 0.0 3.0 26.1 0.0 1.2 7.0 3.9 0.0 2.4 2.7 0.1 0.5 0.0 0.1 0.0 0.4 0.7 1.2 2.6 0.3 12.3 2.4 3.5 0.1 6.1 0.0 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.2 0.0 0.0 0.0 0.4 0.0 6.6 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.6 1.3 5.0 6.1 6.0 3.0 26.1 2.4 2.6 3.5 1.6 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.2 0.0 0.0 0.4 24.4 0.1 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 2.0 0.5 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.3 12.2 0.3 0.1 0.0 4.7 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.1 6.6 0.0 0.2 1.2 0.9 0.0 0.0 0.0 0.3 0.0 0.0 4.2 GRSF1 ENSG00000132463 "G-rich RNA sequence binding factor 1" Q12849 4 70815783-70839897 "Predicted intracellular proteins" "mRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 275.2" "Cell type enhanced" "Detected in all" "monocytes: 301.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036984, HPA036985" Enhanced Enhanced Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "HPA036984: AB_2675415, HPA036985: AB_10672785" "unprognostic (1.45e-3)" "unprognostic (1.82e-2)" "prognostic favorable (1.47e-5)" "unprognostic (8.63e-2)" "unprognostic (6.73e-2)" "unprognostic (4.15e-3)" "prognostic unfavorable (8.29e-5)" "unprognostic (1.94e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (7.68e-2)" "unprognostic (8.05e-2)" "prognostic favorable (2.72e-9)" "unprognostic (6.12e-2)" "unprognostic (1.23e-1)" "unprognostic (1.78e-1)" "unprognostic (9.65e-3)" 38.0 61.2 38.4 36.9 37.7 23.7 37.7 42.5 47.1 36.3 58.9 54.6 43.1 32.5 34.0 42.0 43.0 35.2 80.7 41.0 44.5 55.8 54.4 35.5 47.4 40.3 42.3 38.4 62.0 48.8 21.5 43.8 41.6 39.9 62.7 25.4 83.9 35.3 275.2 32.0 41.3 40.0 40.7 34.6 50.8 32.8 40.9 76.0 45.7 155.0 53.7 50.3 25.8 46.1 116.9 78.1 90.0 94.5 93.5 108.1 128.3 138.2 87.3 102.3 83.5 80.5 117.1 167.6 102.9 143.7 53.0 43.4 161.3 108.6 135.9 91.3 52.8 88.4 75.2 112.4 115.1 130.8 48.7 91.9 102.2 103.6 71.6 123.0 106.9 91.9 102.6 94.7 144.2 124.9 217.4 92.0 96.3 127.1 80.9 88.2 139.8 71.6 126.1 144.0 93.4 84.0 65.3 183.6 234.3 104.7 79.8 63.3 98.4 95.1 99.7 79.4 88.7 78.1 66.2 106.4 78.6 83.6 94.5 12.7 17.4 7.7 10.1 12.3 12.2 7.4 14.6 15.5 28.1 6.1 14.4 12.6 2.0 20.0 15.2 27.2 13.3 8.4 38.4 37.7 42.5 47.1 41.0 44.5 40.3 42.3 41.6 40.7 40.9 46.1 27.8 32.1 36.6 19.6 38.0 50.0 53.7 32.9 48.3 18.2 37.7 28.3 135.5 40.0 30.4 27.6 25.0 106.2 57.4 52.9 74.3 70.3 7.6 53.8 40.4 33.0 69.0 41.2 35.1 61.3 141.3 41.2 65.2 44.5 17.2 60.2 35.0 50.9 63.2 28.6 30.5 73.5 36.7 66.3 53.7 6.7 34.8 45.4 62.2 24.4 301.5 23.8 41.2 21.6 28.0 60.1 46.7 39.1 58.7 65.9 47.1 74.1 27.6 19.6 19.7 38.4 46.2 35.0 61.8 69.7 50.4 77.2 45.1 99.0 89.3 67.0 GSAP "LOC54103, PION" ENSG00000186088 "Gamma-secretase activating protein" A4D1B5 7 77310751-77416349 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;NK-cells: 110.2;Oligodendrocyte precursor cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 12.5;U-937: 17.0" "Region enhanced" "Detected in all" "cerebellum: 15.5" "Low region specificity" "Detected in all" HPA023994 Approved Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA023994: AB_1855386" "prognostic favorable (3.36e-4)" "unprognostic (3.70e-1)" "unprognostic (8.55e-3)" "unprognostic (4.53e-3)" "unprognostic (6.80e-3)" "unprognostic (3.52e-3)" "unprognostic (4.36e-2)" "unprognostic (7.18e-3)" "unprognostic (1.09e-1)" "unprognostic (9.98e-3)" "unprognostic (2.07e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (3.61e-1)" "unprognostic (1.82e-2)" "unprognostic (9.49e-2)" "prognostic favorable (4.15e-5)" 5.3 5.3 2.5 10.9 2.2 9.4 5.9 1.8 3.4 3.7 3.2 5.0 2.6 4.0 3.8 3.1 6.4 7.9 4.9 2.4 4.1 6.3 16.4 18.4 13.1 3.6 2.9 3.6 5.4 11.8 7.4 3.8 3.0 5.4 4.7 10.9 4.7 5.1 2.0 4.4 7.5 3.8 2.8 18.7 7.8 1.9 4.2 6.1 8.3 3.9 13.0 5.9 2.3 4.1 3.8 2.0 0.0 0.0 0.5 2.4 0.4 2.3 7.7 1.2 3.2 0.6 5.4 0.8 0.2 0.1 4.3 1.8 0.1 1.9 3.4 2.5 1.6 4.1 0.2 10.7 3.3 0.3 0.0 0.9 7.0 6.2 12.5 9.2 0.5 0.0 0.1 0.3 10.5 2.1 0.0 8.2 0.6 6.0 2.7 0.0 0.2 0.2 6.9 3.2 0.2 5.7 2.5 1.2 6.3 0.5 2.3 3.4 0.0 2.0 1.4 0.2 7.1 1.5 0.1 1.4 8.8 17.0 1.6 0.0 13.3 1.4 8.5 12.7 5.2 18.6 2.8 6.0 16.3 16.4 3.6 6.1 1.7 16.7 9.4 0.4 0.1 8.2 2.5 2.2 1.8 3.4 2.4 4.1 3.6 2.9 3.0 2.8 4.2 4.1 15.2 76.9 60.8 29.0 53.3 5.2 11.6 19.3 13.6 17.0 12.5 9.8 8.5 11.5 22.8 3.7 16.7 3.2 60.5 0.7 25.4 8.5 0.1 10.2 1.6 9.2 5.4 4.4 28.2 6.2 0.7 4.9 9.7 15.8 13.3 9.8 3.3 17.2 9.7 20.2 51.9 6.1 10.2 38.2 23.3 0.2 5.3 46.5 8.8 42.2 30.8 41.6 110.2 72.4 12.7 6.8 4.6 3.8 15.4 20.0 1.4 12.0 9.8 20.9 6.6 9.8 3.2 2.5 1.5 8.6 4.5 1.6 22.8 2.0 4.6 17.2 GSDME "DFNA5, ICERE-1" ENSG00000105928 "Gasdermin E" O60443 7 24698355-24757940 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Necrosis "Deafness, Non-syndromic deafness, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 168.1;Distal tubular cells: 41.1;Extravillous trophoblasts: 26.5;Hofbauer cells: 39.9;Syncytiotrophoblasts: 104.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 9.0;myeloid DC: 5.9;naive B-cell: 8.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011326, CAB019306" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB019306: , HPA011326: AB_1847629" "unprognostic (1.08e-1)" "unprognostic (1.77e-2)" "unprognostic (6.29e-2)" "unprognostic (6.36e-3)" "unprognostic (6.70e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.35e-2)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.13e-3)" "unprognostic (1.48e-3)" "unprognostic (6.70e-2)" "unprognostic (1.06e-1)" "unprognostic (5.90e-2)" 13.5 7.8 16.4 2.9 16.7 0.5 7.6 13.3 18.0 17.3 9.2 6.4 7.7 24.8 15.3 3.6 14.3 8.5 9.7 18.1 15.0 13.3 4.5 4.4 5.8 19.4 18.7 16.9 2.6 7.3 7.0 35.0 16.1 7.5 2.4 6.3 3.1 21.1 7.8 3.0 26.8 15.1 16.5 1.8 3.9 12.9 14.1 5.8 14.5 5.2 3.8 15.0 10.1 26.6 31.4 21.7 9.6 41.2 51.4 28.6 16.4 24.1 63.6 24.5 34.3 22.9 1.1 0.5 20.6 66.4 81.7 20.5 5.8 105.4 42.8 0.1 2.1 0.8 39.3 48.0 43.0 0.1 1.5 31.3 75.3 43.5 103.1 73.0 42.3 13.8 3.0 5.2 55.3 0.4 1.9 0.8 10.2 0.1 15.7 0.2 33.6 0.0 74.5 21.9 0.4 60.0 36.5 0.6 42.3 24.3 2.2 2.8 27.9 23.1 39.7 31.6 29.2 2.4 0.6 15.5 69.8 0.1 5.8 0.0 1.9 0.0 0.0 0.2 0.0 9.0 0.1 0.0 5.9 8.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 16.4 16.7 13.3 18.0 18.1 15.0 19.4 18.7 16.1 16.5 14.1 26.6 1.0 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.1 3.9 0.0 0.0 0.6 5.5 0.0 168.1 0.0 0.0 41.1 1.9 0.0 0.7 16.9 1.3 0.0 0.0 0.0 0.9 26.5 4.3 0.0 1.0 0.0 4.8 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 8.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 8.8 1.5 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 104.7 0.7 0.9 0.0 0.0 GSE1 KIAA0182 ENSG00000131149 "Gse1 coiled-coil protein" Q14687 16 85169525-85676204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 146.0;Syncytiotrophoblasts: 182.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 24.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 174.6;K-562: 205.4;T-47d: 200.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036365, HPA042090" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA036365: AB_10601762, HPA042090: " "unprognostic (1.12e-2)" "unprognostic (6.29e-2)" "unprognostic (1.12e-1)" "unprognostic (4.57e-2)" "unprognostic (5.31e-2)" "unprognostic (1.63e-1)" "unprognostic (1.76e-1)" "unprognostic (1.77e-1)" "unprognostic (2.60e-1)" "unprognostic (6.41e-2)" "prognostic favorable (5.20e-4)" "unprognostic (2.29e-3)" "unprognostic (1.32e-3)" "unprognostic (8.41e-2)" "unprognostic (8.46e-2)" "unprognostic (3.81e-1)" "unprognostic (1.88e-1)" 27.2 15.2 1.4 14.2 0.7 31.9 22.0 24.4 7.9 16.9 0.0 17.9 15.9 15.1 5.0 12.7 15.9 10.6 23.2 3.9 3.0 12.3 14.2 17.7 11.3 4.5 5.8 23.7 23.4 38.6 28.0 31.7 2.1 12.7 11.5 14.4 30.3 13.6 37.9 18.8 14.8 14.2 0.0 18.4 20.8 14.7 2.0 40.7 19.3 9.3 8.7 13.0 14.1 0.7 19.3 33.6 22.0 55.5 13.9 12.7 174.6 25.3 17.4 13.9 5.2 29.0 25.6 11.2 29.9 28.9 12.5 17.9 35.1 9.7 7.0 21.2 29.7 82.4 33.6 36.5 17.9 38.5 44.8 23.7 22.7 14.9 7.1 14.5 3.7 65.7 205.4 2.0 4.6 129.9 138.1 33.9 38.4 20.7 9.9 89.7 7.4 29.1 12.6 7.2 142.7 99.3 49.8 91.8 4.7 19.9 200.7 94.6 6.4 28.3 35.5 7.9 6.9 30.0 19.5 65.3 16.2 23.8 25.4 2.8 0.7 2.2 1.4 1.3 1.4 1.6 0.5 0.9 1.2 1.5 0.2 1.0 0.6 0.9 3.3 0.0 0.0 0.6 1.4 0.7 24.4 7.9 3.9 3.0 4.5 5.8 2.1 0.0 2.0 0.7 52.9 67.3 68.1 30.3 16.6 14.0 7.3 11.6 21.1 65.0 39.6 16.8 37.0 25.8 24.1 38.6 146.0 52.9 25.5 33.6 1.9 14.9 4.3 48.8 34.7 27.0 59.7 65.6 53.2 12.4 75.9 21.7 39.3 61.6 43.6 80.9 17.2 34.7 12.3 35.3 45.4 67.5 20.3 15.1 24.0 5.5 47.2 17.5 10.6 19.7 12.2 7.1 35.0 14.1 13.7 17.9 20.9 61.3 18.6 14.3 12.6 6.2 30.5 62.3 6.6 15.5 10.1 2.3 18.3 33.5 30.0 182.2 21.5 55.8 25.7 12.3 GSG1 MGC3146 ENSG00000111305 "Germ cell associated 1" Q2KHT4 12 13083532-13103683 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 429.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 10812.1" "Cancer enhanced" "Detected in single" "testis cancer: 1.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 8.8;LHCN-M2: 9.8;RPTEC TERT1: 12.3;U-2 OS: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Intracellular and membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.50e-1)" "unprognostic (2.21e-2)" "unprognostic (6.33e-2)" "unprognostic (2.36e-2)" "unprognostic (1.34e-1)" "unprognostic (8.01e-2)" "unprognostic (1.04e-1)" "unprognostic (4.52e-1)" "unprognostic (6.85e-2)" "unprognostic (8.23e-2)" "unprognostic (5.91e-2)" "unprognostic (3.20e-3)" "unprognostic (1.48e-1)" "unprognostic (3.65e-2)" "unprognostic (1.79e-1)" "unprognostic (6.32e-3)" 0.1 0.0 0.6 0.2 0.9 0.8 0.4 1.7 1.4 0.1 1.3 0.1 1.4 0.1 0.6 0.1 0.0 0.2 0.1 0.7 0.5 0.5 0.1 0.1 0.3 0.0 0.0 0.1 4.8 0.0 0.2 0.2 0.0 0.4 0.2 30.4 0.1 0.0 0.3 0.2 0.7 0.0 0.0 0.2 0.1 429.9 0.1 0.1 0.1 0.0 0.1 0.0 0.1 1.4 0.1 0.4 0.3 0.1 2.0 1.2 0.4 0.2 0.4 0.3 0.4 0.2 0.1 0.2 0.1 8.8 0.6 0.1 0.1 0.0 0.8 0.2 0.0 0.2 0.6 0.3 0.0 0.2 0.1 0.8 0.0 1.6 0.1 0.1 0.0 0.1 0.1 1.6 9.8 0.2 0.1 1.0 2.1 0.1 0.2 0.1 3.5 0.1 12.3 0.2 0.6 0.2 0.3 0.0 0.1 0.3 0.0 1.4 0.1 0.5 5.9 0.3 0.3 0.5 0.3 0.1 2.5 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.9 1.7 1.4 0.7 0.5 0.0 0.0 0.0 0.0 0.1 1.4 0.1 3.2 1.1 0.3 0.0 0.1 0.1 0.0 0.0 134.9 0.1 0.0 0.3 1.5 0.0 0.0 6.2 0.1 0.0 0.0 1.9 0.6 2248.2 0.1 0.2 2.8 27.5 2.7 1.8 0.0 0.1 0.7 0.0 0.1 0.0 0.0 1.4 0.0 0.6 1.7 0.8 2.0 2.0 0.3 0.0 10812.1 53.4 2.9 0.0 1.0 0.1 6.7 0.0 0.0 0.1 0.0 1.2 39.9 0.0 0.1 0.1 0.0 0.0 16.1 6.6 0.4 0.1 57.0 27.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 GSK3A ENSG00000105723 "Glycogen synthase kinase 3 alpha" P49840 19 42226225-42242625 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004422, HPA028423" Approved Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "CAB004422: AB_627680, HPA028423: AB_10612116" "unprognostic (5.46e-2)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.02e-4)" "unprognostic (1.35e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (3.80e-3)" "unprognostic (2.27e-1)" "unprognostic (2.87e-1)" "unprognostic (4.99e-2)" "unprognostic (3.36e-1)" "unprognostic (2.69e-1)" "unprognostic (2.77e-2)" "unprognostic (4.49e-2)" "unprognostic (7.22e-2)" "unprognostic (8.22e-3)" 30.6 43.3 37.5 22.1 44.0 30.7 29.4 33.6 90.2 34.5 13.7 39.4 40.9 38.1 21.7 40.2 31.8 18.7 45.8 47.0 30.9 39.2 30.4 30.4 23.7 39.1 30.9 34.5 29.6 34.4 32.1 19.9 37.6 33.3 21.1 32.6 31.7 25.9 79.2 42.9 37.1 23.0 20.5 31.2 35.4 30.6 38.2 32.9 29.6 42.0 22.7 37.7 33.0 49.5 57.0 102.1 54.3 53.2 30.3 29.5 25.9 42.7 36.1 49.6 46.0 39.0 39.6 41.0 39.6 33.9 44.8 25.6 49.5 51.3 38.5 33.8 74.5 41.5 41.3 42.7 42.7 51.7 54.0 27.2 45.8 41.9 47.7 44.8 46.5 34.7 73.9 63.0 41.1 80.0 87.7 39.0 42.8 84.5 40.0 58.4 33.8 30.4 43.4 76.1 63.7 67.5 52.8 71.6 36.6 42.8 39.5 69.5 40.6 52.0 40.9 31.0 71.9 65.8 82.8 38.7 66.4 49.8 58.2 0.9 0.5 1.4 0.5 0.8 0.9 0.3 0.3 0.7 0.2 0.2 0.2 0.8 1.7 0.3 0.4 0.6 0.5 0.7 37.5 44.0 33.6 90.2 47.0 30.9 39.1 30.9 37.6 20.5 38.2 49.5 45.6 6.4 16.2 5.2 16.4 24.6 17.7 7.3 14.8 40.8 35.0 39.2 12.9 17.2 7.9 16.5 62.6 23.4 31.4 42.3 3.9 15.2 8.6 19.6 21.5 26.6 23.4 28.6 15.1 17.2 25.3 21.3 16.8 25.0 2.5 27.2 18.2 13.9 20.3 60.6 14.9 29.7 6.1 21.3 15.4 14.6 17.7 25.2 16.0 8.4 14.4 41.8 21.6 11.1 12.2 24.2 24.3 16.6 12.6 29.0 45.0 16.0 5.9 47.0 6.6 50.4 27.4 16.4 19.4 20.2 28.1 44.1 20.6 42.6 28.8 30.1 GSK3B ENSG00000082701 "Glycogen synthase kinase 3 beta" P49841 3 119821321-120094994 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Carbohydrate metabolism, Differentiation, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 218.7;Inhibitory neurons: 246.3;Microglial cells: 197.7;Oligodendrocyte precursor cells: 241.8;Oligodendrocytes: 202.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016263, HPA028017" Approved Supported Nucleoplasm No No "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB016263: AB_2279451, HPA028017: AB_10600708" "unprognostic (1.09e-2)" "unprognostic (2.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-3)" "unprognostic (1.15e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (8.20e-5)" "unprognostic (3.39e-2)" "unprognostic (1.11e-1)" "unprognostic (1.67e-2)" "unprognostic (1.05e-3)" "unprognostic (6.79e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.39e-1)" "unprognostic (2.58e-1)" "unprognostic (1.28e-2)" "unprognostic (1.16e-1)" 11.0 13.6 9.2 11.7 9.5 15.1 11.2 16.6 16.9 10.0 0.0 11.7 12.3 10.3 11.1 13.8 10.1 11.1 18.2 8.2 13.8 12.0 14.8 13.9 10.4 15.2 15.3 9.3 10.7 17.3 7.1 16.3 16.5 10.0 12.4 23.6 13.2 9.3 17.5 16.3 15.3 13.3 4.9 12.9 12.6 23.1 9.6 20.0 15.1 18.0 11.7 12.0 9.5 12.5 59.3 22.7 46.8 25.5 31.9 29.5 50.3 36.6 57.6 28.3 29.3 25.9 23.8 24.1 19.1 43.0 33.8 46.0 22.2 59.1 45.8 15.5 6.6 42.2 18.4 16.6 35.6 31.6 49.9 34.3 39.5 27.0 56.8 27.3 31.5 29.3 13.6 34.6 40.5 25.1 44.0 10.7 25.2 23.3 28.3 16.9 41.0 22.2 25.1 45.3 37.1 22.6 38.5 29.0 44.1 41.1 30.9 27.0 40.0 45.5 55.1 12.7 20.6 31.9 35.2 44.8 29.4 22.0 33.9 1.0 1.8 6.3 0.7 1.6 1.2 0.5 1.0 1.7 1.4 0.7 0.9 0.8 6.6 0.5 2.1 1.1 1.2 0.8 9.2 9.5 16.6 16.9 8.2 13.8 15.2 15.3 16.5 4.9 9.6 12.5 39.3 32.1 26.7 113.6 28.3 50.9 37.8 22.2 46.1 63.2 21.9 17.0 39.7 20.0 21.4 18.4 60.5 27.0 29.0 37.3 11.7 26.9 138.2 25.2 31.6 31.5 26.9 15.4 218.7 32.0 49.3 25.1 46.4 32.5 17.2 18.1 25.0 22.9 21.5 143.0 246.3 22.3 20.3 27.3 29.2 48.1 13.1 33.4 35.6 197.7 35.5 31.6 22.6 241.8 202.5 49.0 23.4 19.9 29.0 28.7 35.8 17.3 16.3 42.4 13.1 24.4 38.2 38.8 29.3 50.8 41.1 43.0 36.4 32.7 25.9 41.6 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 GSPT1 "eRF3a, ETF3A, GST1" ENSG00000103342 "G1 to S phase transition 1" P15170 16 11868128-11916082 "Plasma proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Protein biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052488, HPA074588" Approved Approved Vesicles,Cytosol NA NA 210000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol Vesicles "HPA052488: AB_2681849, HPA074588: " "unprognostic (4.13e-2)" "unprognostic (1.66e-1)" "prognostic favorable (2.10e-5)" "unprognostic (1.64e-1)" "unprognostic (2.05e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (7.94e-4)" "unprognostic (2.38e-1)" "unprognostic (2.31e-1)" "unprognostic (1.74e-1)" "unprognostic (1.41e-3)" "unprognostic (1.65e-1)" "prognostic favorable (3.06e-5)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.61e-3)" "unprognostic (3.13e-2)" 60.8 57.5 22.3 49.5 24.7 76.3 46.0 24.4 33.3 42.0 27.4 56.0 33.8 34.5 46.6 67.9 30.1 35.2 53.4 23.9 24.5 53.6 76.3 47.7 55.4 25.0 23.1 33.3 62.2 62.7 27.5 50.0 26.2 47.8 59.6 35.3 41.0 41.8 127.0 43.5 34.3 46.9 25.0 40.2 49.8 68.7 23.1 56.3 57.7 97.8 82.0 85.7 39.6 29.3 220.1 212.9 116.1 161.0 164.2 169.3 167.5 238.0 245.9 187.1 185.4 153.1 197.8 295.7 303.9 207.5 130.1 164.3 297.8 220.3 312.9 142.4 153.6 202.0 163.1 325.5 137.9 258.7 103.5 133.5 170.0 212.0 288.3 122.4 210.4 146.2 331.7 148.7 220.0 211.2 219.8 134.0 232.9 163.0 120.1 256.4 200.5 345.6 184.7 189.3 186.4 99.6 342.0 256.3 144.2 164.3 222.4 122.6 163.3 206.8 129.5 151.5 190.3 146.6 233.2 253.8 145.4 258.1 128.5 1.4 5.8 7.7 6.3 11.1 8.8 7.9 8.1 7.7 7.0 6.5 8.2 8.1 1.9 7.2 9.9 3.8 10.5 4.3 22.3 24.7 24.4 33.3 23.9 24.5 25.0 23.1 26.2 25.0 23.1 29.3 69.4 76.9 160.2 39.5 92.3 242.2 232.0 47.1 170.8 47.7 95.0 61.6 123.4 57.2 69.1 86.5 50.1 76.1 94.5 88.1 103.7 58.9 94.9 109.0 95.6 74.4 66.6 328.5 61.6 63.4 118.3 77.2 81.1 153.9 24.7 93.2 43.5 77.9 75.2 52.2 47.0 107.2 32.6 60.8 116.3 51.6 47.8 80.9 64.0 35.6 50.1 43.6 25.7 38.7 42.9 73.0 66.9 47.4 166.2 271.0 38.3 120.3 52.7 41.5 59.2 94.6 123.0 138.3 83.5 198.5 257.7 102.1 132.1 128.1 114.1 270.4 GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656099-109674836 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 149.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 382.8;Proximal tubular cells: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "eosinophil: 351.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 351.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Cytokinetic bridge" "HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "prognostic favorable (9.96e-5)" "unprognostic (1.96e-3)" "unprognostic (7.49e-2)" "unprognostic (9.92e-3)" "unprognostic (1.48e-1)" "unprognostic (1.08e-2)" "unprognostic (8.47e-2)" "unprognostic (3.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.76e-2)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" 22.3 31.1 19.7 15.3 23.7 5.9 22.5 19.1 23.8 24.5 40.0 45.4 149.5 22.6 24.3 31.3 22.2 17.8 33.5 19.2 19.9 45.9 41.2 14.6 11.8 20.7 20.9 42.9 21.2 57.8 18.6 7.6 20.2 25.8 38.5 12.5 21.2 41.0 92.4 20.6 99.4 25.7 21.1 30.2 28.8 15.1 20.1 9.9 27.7 45.5 15.6 36.8 28.8 20.2 13.5 6.0 10.5 78.9 23.0 35.1 13.4 4.3 34.1 9.8 12.8 43.3 1.5 12.5 16.1 19.1 19.3 13.6 27.1 14.4 6.2 18.9 0.0 27.4 23.5 38.8 37.1 9.5 31.8 22.3 14.0 12.6 0.0 27.5 8.1 31.7 12.8 18.4 6.9 12.7 8.1 41.9 8.2 56.3 31.9 16.9 5.8 18.5 38.8 9.6 7.4 17.6 0.2 68.2 54.9 7.8 18.6 20.1 3.6 11.4 44.0 12.5 6.3 27.0 51.4 1.1 37.1 13.9 32.5 11.9 14.5 351.7 12.2 14.5 7.4 17.0 9.3 14.1 37.8 14.9 8.9 10.7 1.8 12.8 3.6 12.6 14.1 12.6 19.7 23.7 19.1 23.8 19.2 19.9 20.7 20.9 20.2 21.1 20.1 20.2 6.9 9.6 2.7 11.4 9.9 18.1 27.3 17.9 18.8 6.2 14.7 19.0 30.2 21.5 9.5 31.3 0.0 21.0 13.9 53.0 101.8 45.9 3.0 4.5 10.8 8.6 7.2 4.2 3.3 57.7 18.6 22.9 13.3 5.4 21.0 13.3 14.3 35.7 35.6 5.0 3.3 45.9 6.1 17.2 26.0 6.4 30.1 14.9 40.9 2.8 14.8 23.9 17.5 5.0 3.4 35.4 38.6 24.8 13.3 6.7 382.8 109.8 7.5 5.4 32.9 15.3 23.2 7.0 7.3 23.0 15.3 8.8 11.2 12.6 96.7 26.9 GSX2 Gsh2 ENSG00000180613 "GS homeobox 2" Q9BZM3 4 54099523-54102498 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "glioma: 2.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" NA NA "Cluster 65: Brain - Ion transport" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (4.48e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (1.89e-1)" 0.0 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.6 0.2 0.2 0.2 0.2 0.4 0.3 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GTDC1 "FLJ11753, Hmat-Xa" ENSG00000121964 "Glycosyltransferase like domain containing 1" Q4AE62 2 143938068-144332568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 330.7;Inhibitory neurons: 188.0;Microglial cells: 130.2;Oligodendrocyte precursor cells: 196.6;Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036694 Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA036694: AB_10671709" "unprognostic (1.44e-1)" "unprognostic (1.22e-1)" "unprognostic (9.00e-3)" "unprognostic (3.36e-2)" "unprognostic (5.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.81e-7)" "unprognostic (8.01e-2)" "unprognostic (4.13e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-3)" "unprognostic (6.96e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (2.44e-1)" "unprognostic (8.23e-2)" "unprognostic (6.31e-3)" "unprognostic (1.89e-1)" 15.2 12.6 15.9 7.5 18.0 14.2 9.4 11.7 21.1 11.8 4.2 7.1 4.2 6.7 9.4 7.4 5.8 10.1 15.7 17.3 14.3 9.6 6.7 7.8 11.0 15.4 14.7 12.0 7.2 7.4 4.2 9.5 15.4 6.1 6.7 7.7 6.1 5.8 10.0 5.1 4.8 5.9 17.2 13.5 5.2 12.2 14.3 8.7 10.5 11.3 11.6 9.5 5.5 24.1 6.9 2.8 20.0 3.7 20.1 18.4 6.0 4.7 11.9 10.3 14.2 3.1 6.3 14.8 3.3 8.5 6.6 1.9 4.0 7.1 21.9 19.2 4.7 23.0 2.6 3.3 8.3 9.4 12.0 12.8 17.1 11.1 16.2 7.0 14.9 6.1 4.2 16.8 23.7 3.2 2.5 10.3 5.7 5.3 4.5 7.0 10.4 4.0 11.4 14.0 10.2 7.9 9.1 7.7 9.3 12.4 5.1 10.5 9.2 11.4 8.3 5.1 6.0 10.6 0.0 8.5 6.6 6.2 15.6 2.3 2.6 7.9 5.5 2.4 11.8 4.3 3.6 9.3 2.1 3.5 0.8 5.9 11.3 8.5 2.7 0.7 5.1 3.6 15.9 18.0 11.7 21.1 17.3 14.3 15.4 14.7 15.4 17.2 14.3 24.1 7.7 9.6 23.2 82.3 11.2 7.1 4.4 6.4 4.0 20.4 5.2 5.0 18.5 4.3 14.9 5.5 4.2 4.1 13.6 6.1 5.9 4.5 9.9 3.3 11.4 9.6 4.2 9.4 330.7 10.5 5.2 16.0 4.6 5.6 17.7 15.5 20.3 3.8 10.2 18.5 188.0 3.2 4.1 18.3 11.8 7.7 12.8 16.4 5.4 130.2 11.6 10.8 18.6 196.6 399.6 9.4 4.0 13.9 8.6 4.2 2.6 7.7 13.4 3.9 13.1 25.2 17.0 5.4 23.5 4.9 4.7 4.2 19.7 14.8 3.7 8.7 GTF3C3 "TFIIIC102, TFiiiC2-102" ENSG00000119041 "General transcription factor IIIC subunit 3" Q9Y5Q9 2 196763035-196799725 "Predicted intracellular proteins, Predicted membrane proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069179 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear membrane" "HPA069179: AB_2686099" "unprognostic (1.44e-1)" "unprognostic (2.63e-2)" "unprognostic (1.89e-1)" "unprognostic (4.52e-2)" "unprognostic (5.88e-2)" "unprognostic (3.64e-2)" "prognostic unfavorable (1.26e-6)" "unprognostic (1.92e-1)" "unprognostic (9.28e-2)" "unprognostic (1.39e-1)" "unprognostic (2.09e-1)" "unprognostic (5.62e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-1)" "unprognostic (2.72e-1)" "unprognostic (1.70e-1)" "unprognostic (3.08e-2)" 11.0 10.9 18.1 9.6 20.4 36.8 19.5 25.1 23.1 10.9 23.8 10.8 10.2 12.2 15.1 11.4 11.9 19.6 10.0 19.8 19.9 9.5 12.9 10.5 18.8 21.7 19.0 13.8 13.1 13.6 9.0 12.5 25.9 10.2 13.1 18.6 9.7 10.0 13.6 20.9 10.8 14.3 17.9 13.8 12.1 13.9 19.5 13.4 15.1 7.3 10.9 11.6 9.4 31.8 14.4 19.2 28.4 22.2 13.1 19.4 28.0 26.2 16.3 24.7 25.0 41.4 23.0 29.8 15.9 15.7 24.1 19.2 24.4 23.3 28.7 35.0 26.6 37.2 59.9 38.6 21.8 32.8 28.9 25.8 21.4 17.8 25.0 21.9 22.6 25.7 45.6 54.6 14.9 34.0 28.6 29.2 16.9 16.9 29.3 24.4 20.7 19.8 17.6 43.2 22.6 20.5 16.7 14.6 17.8 35.9 15.4 21.1 15.0 21.2 15.1 16.7 19.3 26.0 34.4 22.2 21.8 24.4 16.9 8.4 4.7 4.4 3.9 3.1 3.5 4.8 3.5 4.0 2.8 6.8 4.2 4.0 4.4 4.8 5.8 4.3 4.8 2.3 18.1 20.4 25.1 23.1 19.8 19.9 21.7 19.0 25.9 17.9 19.5 31.8 17.4 22.4 16.0 19.2 11.6 4.0 12.2 16.6 10.2 18.1 8.8 8.8 35.8 7.2 21.4 14.7 18.8 15.3 18.1 7.7 13.7 12.4 4.4 18.2 17.4 17.0 12.5 19.1 24.7 12.3 12.6 12.9 11.2 13.3 14.0 24.7 12.8 8.2 13.5 0.0 29.8 10.1 16.2 12.7 5.0 4.6 13.4 11.8 7.2 27.2 22.0 12.5 9.2 23.1 38.5 14.7 6.4 10.9 16.3 8.4 12.9 10.9 37.2 15.6 6.6 10.1 13.6 44.7 24.8 11.6 5.5 15.7 12.2 18.2 11.9 9.4 GTPBP10 "DKFZP686A10121, FLJ38242, OBGH2" ENSG00000105793 "GTP binding protein 10" A4D1E9 7 90335223-90391453 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021076 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "HPA021076: AB_1850411" "unprognostic (2.74e-1)" "unprognostic (2.91e-1)" "unprognostic (2.35e-1)" "unprognostic (6.17e-2)" "unprognostic (1.35e-1)" "unprognostic (3.18e-1)" "unprognostic (3.56e-1)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (5.38e-2)" "unprognostic (2.32e-1)" "unprognostic (1.39e-1)" "prognostic favorable (6.76e-5)" "unprognostic (8.34e-2)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" "unprognostic (2.72e-3)" 8.5 7.2 3.2 8.9 3.2 6.5 10.6 5.3 5.7 7.0 1.9 8.8 8.8 7.6 6.4 8.2 6.3 5.6 10.1 3.0 4.3 12.5 18.7 5.7 11.0 3.3 2.8 8.6 7.6 8.1 4.5 6.1 4.0 6.9 9.6 7.2 6.1 5.3 12.3 6.8 7.1 7.1 3.9 7.3 10.7 11.3 3.5 12.7 9.8 10.0 9.7 9.5 5.6 4.3 33.9 21.1 14.1 21.3 17.1 15.3 23.2 21.2 13.9 19.5 15.4 31.1 25.0 42.2 34.6 14.5 41.6 21.3 32.4 28.3 25.3 26.5 16.6 17.4 12.8 16.4 16.3 51.0 14.9 18.3 12.1 32.4 64.3 15.5 11.5 35.0 64.8 30.1 17.6 34.6 35.8 14.5 17.4 30.8 25.5 22.7 41.3 35.2 14.3 18.4 17.4 16.3 27.2 41.3 41.2 20.1 20.0 21.9 21.1 27.3 31.9 48.9 41.2 22.6 30.7 59.3 20.5 35.4 29.5 23.6 5.3 9.4 6.3 7.4 10.9 11.7 10.2 7.7 6.4 9.2 10.8 10.2 5.1 7.8 4.5 5.7 13.3 5.6 3.2 3.2 5.3 5.7 3.0 4.3 3.3 2.8 4.0 3.9 3.5 4.3 11.0 12.8 21.1 21.5 17.6 5.9 8.5 13.5 9.6 12.6 9.8 11.0 14.3 7.2 17.0 16.5 14.6 7.6 9.7 6.2 13.7 8.7 21.8 8.8 12.1 9.4 9.6 12.8 29.7 15.8 7.2 10.8 10.2 8.9 12.0 12.7 8.6 14.3 6.4 5.0 35.5 7.4 14.2 7.5 6.0 4.4 9.3 7.4 7.2 42.2 7.4 11.2 9.2 36.7 50.8 10.2 4.9 9.4 7.4 8.4 7.8 21.8 15.3 12.4 6.6 18.9 10.5 26.2 18.9 12.0 6.1 6.7 15.5 15.6 9.1 8.4 GTPBP3 "FLJ14700, GTPBG3, MSS1, MTGP1, THDF1" ENSG00000130299 "GTP binding protein 3, mitochondrial" Q969Y2 19 17334920-17342731 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042158 Approved Supported Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Mitochondria "HPA042158: AB_10964400" "unprognostic (1.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (3.08e-3)" "unprognostic (1.34e-1)" "unprognostic (2.18e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (6.32e-2)" "unprognostic (1.82e-1)" "unprognostic (2.70e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (2.81e-4)" "prognostic unfavorable (1.64e-4)" "unprognostic (4.94e-3)" "unprognostic (1.21e-1)" "unprognostic (2.56e-1)" "unprognostic (1.79e-1)" 8.0 13.5 6.8 5.1 5.9 4.9 9.1 6.1 7.0 10.6 6.0 8.8 5.5 8.5 1.8 13.1 9.6 2.1 8.7 6.3 7.5 11.3 14.1 7.6 6.5 9.0 7.1 10.2 12.2 5.3 8.8 3.3 9.0 10.5 2.9 4.1 10.2 3.9 9.2 15.1 9.4 2.8 6.2 12.7 9.3 3.0 7.0 3.5 8.8 3.1 4.3 8.9 10.4 6.5 19.7 11.6 10.6 13.8 3.5 3.3 51.2 9.1 3.8 8.2 8.0 16.2 15.6 29.8 22.8 3.4 5.8 17.2 13.5 7.8 6.7 24.9 62.6 17.8 18.4 21.4 4.6 19.3 11.2 3.4 11.2 7.6 9.7 5.7 6.6 20.9 34.6 13.0 4.2 15.7 23.2 17.2 22.4 12.2 51.5 27.4 8.2 28.3 7.6 8.8 24.7 22.0 9.8 14.9 12.9 7.0 13.2 7.9 7.2 12.6 11.3 28.0 16.3 21.9 36.7 35.4 10.0 25.0 9.8 0.4 2.3 0.4 4.8 3.2 4.0 3.0 4.5 4.3 3.6 4.1 4.9 4.6 0.7 5.2 1.7 6.7 3.3 2.8 6.8 5.9 6.1 7.0 6.3 7.5 9.0 7.1 9.0 6.2 7.0 6.5 10.5 3.2 5.3 11.8 10.8 17.1 9.3 11.4 13.6 20.3 14.9 14.9 7.2 4.3 6.1 5.5 31.3 21.4 10.2 5.9 7.9 12.5 0.3 5.2 7.7 9.7 3.0 12.0 6.2 10.9 25.3 9.0 9.2 7.9 2.5 15.7 8.6 9.8 10.1 11.8 9.4 9.7 12.2 5.6 7.7 0.2 11.8 6.2 10.6 2.8 8.6 8.3 12.3 8.0 8.3 10.8 7.5 13.5 18.0 9.7 9.1 7.1 5.9 20.7 6.6 7.2 10.8 2.9 4.6 11.5 17.5 8.3 12.6 15.9 13.2 6.4 GUCA2A "GUCA2, STARA" ENSG00000197273 "Guanylate cyclase activator 2A" Q02747 1 42162690-42164745 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "intestine: 927.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 3728.7;Paneth cells: 17085.1;Proximal enterocytes: 12113.5" "Group enriched" "Detected in many" 7 "colorectal cancer: 31.6;urothelial cancer: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 52.1" "Not detected" "Not detected" HPA018215 Enhanced "Secreted to blood" NA NA 18000000 "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA018215: AB_1850443" "unprognostic (7.98e-3)" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (9.07e-2)" "unprognostic (1.14e-1)" "unprognostic (8.06e-2)" "unprognostic (2.89e-1)" "unprognostic (3.10e-1)" "unprognostic (9.15e-2)" 0.8 0.1 0.0 3.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 716.9 56.5 0.9 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.4 0.2 1.2 0.7 0.0 0.0 0.1 1.2 0.0 0.2 7.3 0.0 0.1 725.9 0.0 0.0 2.0 0.1 0.0 927.5 17.2 0.0 0.2 0.7 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 52.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3728.7 0.0 2.6 0.1 0.0 0.0 0.0 47.7 0.0 0.0 1.1 4.4 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 421.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17085.1 0.0 0.0 0.0 12113.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 3.8 0.0 206.6 0.2 GUCA2B ENSG00000044012 "Guanylate cyclase activator 2B" Q16661 1 42153410-42155820 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 143.1" "Cell type enriched" "Detected in some" 7 "Paneth cells: 18841.5" "Cancer enhanced" "Detected in many" "liver cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 1.4;CACO-2: 3.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Secreted to blood" NA NA 77700 1200000 "Cluster 7: Monocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.59e-2)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (6.22e-2)" "unprognostic (1.86e-1)" 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 89.4 36.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 5.5 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 23.3 0.0 0.0 0.6 0.0 0.1 143.1 0.6 0.0 0.0 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 1098.8 0.0 0.9 1.0 0.0 0.0 0.0 22.8 0.0 0.0 47.9 0.3 0.0 0.0 0.0 22.3 0.0 0.4 3.1 0.1 0.0 0.0 107.2 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 18841.5 0.0 0.0 0.0 2568.9 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 1.3 0.0 55.3 0.9 GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 213.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" NA NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA036322: AB_10670796, HPA036323: AB_2675059" "unprognostic (1.54e-2)" "unprognostic (6.49e-2)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (7.00e-3)" "unprognostic (1.91e-1)" "unprognostic (3.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.98e-1)" "unprognostic (5.06e-1)" "unprognostic (1.45e-1)" 28.4 18.2 11.0 22.3 12.3 84.2 80.9 12.0 16.1 26.7 14.3 38.2 36.1 26.2 41.8 16.4 24.6 27.6 19.6 10.7 11.5 25.1 104.0 35.7 25.6 13.2 12.2 19.9 33.6 30.3 12.6 48.2 13.2 20.2 41.9 9.7 32.9 21.2 10.9 18.8 29.8 19.1 11.9 34.0 38.1 19.5 13.0 22.7 27.7 14.4 24.0 27.3 15.4 13.5 67.0 26.5 25.2 56.3 80.9 49.1 35.3 21.3 56.8 45.0 42.1 37.0 67.8 30.9 32.3 26.8 24.1 27.5 16.5 25.1 26.8 27.3 34.1 41.5 40.9 27.3 39.7 89.6 67.1 33.4 26.7 26.3 33.3 54.5 39.3 18.0 63.2 213.5 30.5 50.3 34.2 92.0 17.9 103.0 21.0 34.4 55.9 172.4 29.4 42.8 36.2 32.7 55.6 129.1 72.3 29.9 71.1 88.8 28.5 55.3 49.3 21.8 53.6 119.6 151.9 50.0 41.0 116.3 68.3 26.0 80.1 65.7 32.0 103.0 28.4 27.7 24.7 28.4 80.5 22.6 16.8 19.5 13.2 46.6 93.5 34.2 34.5 51.4 11.0 12.3 12.0 16.1 10.7 11.5 13.2 12.2 13.2 11.9 13.0 13.5 53.1 51.3 58.7 10.1 33.0 18.0 32.0 51.9 29.0 12.2 26.1 19.9 12.2 48.6 48.9 29.5 8.4 81.9 32.6 52.2 5.9 41.1 59.1 28.9 26.5 39.7 43.0 47.1 12.3 30.3 61.2 49.5 49.5 49.4 36.8 38.3 37.9 72.7 126.4 16.8 10.6 51.6 30.5 88.1 33.2 46.7 43.2 78.0 39.2 14.0 44.8 28.0 20.6 8.5 14.2 29.4 49.5 28.6 87.5 25.3 50.6 26.8 43.2 20.1 26.3 27.1 26.0 49.6 31.0 16.0 14.8 66.9 32.2 24.4 44.3 29.6 GXYLT1 "FLJ43151, GLT8D3" ENSG00000151233 "Glucoside xylosyltransferase 1" Q4G148 12 42081845-42144874 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 3200000 "Cluster 52: Eosinophils - Transcription" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 32: U-937 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.09e-2)" "unprognostic (1.16e-1)" "unprognostic (1.53e-1)" "unprognostic (5.07e-1)" "unprognostic (1.22e-1)" "unprognostic (9.89e-2)" "unprognostic (5.22e-3)" "unprognostic (1.77e-2)" "unprognostic (4.42e-3)" "unprognostic (1.46e-2)" "unprognostic (1.64e-2)" "unprognostic (3.20e-1)" "unprognostic (1.92e-2)" "unprognostic (8.16e-2)" "unprognostic (2.93e-1)" "unprognostic (3.96e-2)" "prognostic favorable (3.91e-4)" 5.8 4.8 4.0 5.9 4.3 7.5 4.9 4.6 3.4 4.0 4.2 4.1 4.0 3.9 3.7 3.2 4.5 4.0 3.0 3.4 5.7 6.4 12.2 5.5 5.2 5.0 4.6 5.5 4.2 6.0 3.6 11.1 4.7 4.1 4.9 6.1 3.5 3.3 2.4 4.2 5.6 3.7 5.0 6.7 4.6 9.5 4.5 6.8 8.9 3.9 4.6 4.6 3.4 4.9 12.9 10.8 12.2 11.9 8.5 22.1 45.6 28.4 19.0 20.7 20.9 25.1 25.9 11.2 21.7 15.8 14.9 6.0 20.6 9.2 38.1 18.7 23.2 18.4 9.1 20.5 13.4 20.1 16.9 17.1 7.8 31.6 13.9 12.3 27.7 12.6 11.8 19.3 26.7 8.9 13.0 12.2 14.8 4.9 10.2 6.1 24.6 10.0 12.5 19.1 6.2 10.5 20.2 11.4 16.8 22.6 23.4 15.6 23.9 14.7 49.8 8.7 18.1 25.2 30.4 14.1 19.9 53.8 9.2 0.1 0.6 1.8 0.4 1.2 0.2 0.4 0.6 0.5 1.0 0.4 0.5 0.5 0.4 0.9 1.5 0.2 0.7 0.3 4.0 4.3 4.6 3.4 3.4 5.7 5.0 4.6 4.7 5.0 4.5 4.9 22.1 16.0 15.0 10.1 21.5 3.2 14.3 7.9 8.6 9.0 13.3 8.6 7.4 7.2 8.8 35.0 8.4 42.7 34.2 10.5 1.9 9.5 1.6 7.2 11.9 16.4 3.0 8.0 14.3 10.4 39.8 15.7 6.6 10.7 19.1 57.6 24.3 27.8 13.8 15.2 16.1 9.5 6.1 16.2 7.4 3.4 11.8 13.2 5.4 25.3 20.5 10.3 15.5 16.6 17.8 8.9 12.5 7.5 21.5 14.5 12.3 3.9 12.1 15.5 13.1 13.3 11.7 25.2 33.4 11.0 4.4 45.6 22.2 13.9 9.1 12.7 GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888046-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Endometrial stromal cells: 45.4;Fibroblasts: 23.0;Late spermatids: 27.1;Oligodendrocytes: 61.3;Skeletal myocytes: 40.0;Theca cells: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 22.3;JURKAT: 22.1;MOLT-4: 36.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: AB_2685988" "unprognostic (9.43e-2)" "unprognostic (8.87e-3)" "unprognostic (1.90e-1)" "unprognostic (4.77e-2)" "unprognostic (3.33e-2)" "unprognostic (7.04e-2)" "unprognostic (4.79e-3)" "unprognostic (5.29e-2)" "unprognostic (5.25e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (3.22e-3)" "unprognostic (4.70e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.42e-5)" 6.0 3.8 2.6 5.2 5.3 1.8 4.0 4.3 3.2 5.7 2.6 3.7 0.6 5.6 2.5 3.2 5.1 10.1 13.6 2.0 2.4 0.9 0.3 3.8 1.5 6.2 5.8 16.5 4.2 2.4 1.9 4.0 4.1 3.3 2.0 0.4 5.3 4.0 0.8 1.7 1.2 5.5 5.3 0.7 1.3 5.8 4.6 6.7 8.8 1.5 1.0 5.7 3.6 6.9 0.2 1.8 0.1 11.2 9.9 19.3 1.7 1.8 4.2 4.0 9.8 0.5 1.2 0.0 3.1 4.9 22.3 0.1 1.0 2.2 3.8 0.0 1.3 0.0 7.2 12.4 12.6 4.9 0.0 18.8 1.1 9.7 1.6 6.0 0.0 22.1 5.8 0.1 2.4 2.7 36.5 0.1 6.6 0.1 2.2 0.2 9.5 0.0 1.3 1.7 1.1 5.0 9.8 0.5 1.3 2.0 3.7 1.5 0.1 4.3 13.5 13.3 6.5 1.0 0.1 0.2 11.1 2.3 7.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.3 0.0 2.6 5.3 4.3 3.2 2.0 2.4 6.2 5.8 4.1 5.3 4.6 6.9 1.6 3.2 2.6 7.2 0.1 1.9 1.9 5.3 0.0 0.6 1.5 7.6 14.6 2.8 2.3 0.0 0.0 0.2 1.5 1.4 0.0 0.1 47.9 5.7 45.4 0.6 3.5 0.0 8.3 1.1 0.3 23.0 0.0 7.5 0.0 8.0 0.7 0.0 0.4 0.0 9.0 2.9 0.0 0.0 4.0 27.1 8.1 0.5 0.0 12.2 0.0 2.5 0.0 3.0 61.3 0.8 0.4 7.2 0.0 2.0 0.6 0.5 2.1 0.4 0.0 40.0 3.9 2.5 4.2 0.2 0.4 0.8 0.4 22.9 1.6 0.4 GYPB "CD235b, GPB, MNS, SS" ENSG00000250361 "Glycophorin B (MNS blood group)" P06028 4 143996104-144019380 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "bone marrow: 63.2" "Cell type enriched" "Detected in some" 450 "Erythroid cells: 1351.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HEL: 159.0" "Intracellular and membrane" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" 0.2 0.0 0.0 0.0 0.3 63.2 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.3 0.5 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.4 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 159.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 0.0 0.0 0.2 0.1 0.1 0.0 1351.4 3.0 0.0 1.2 0.2 0.0 0.0 0.0 2.1 0.0 0.9 1.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.0 GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102646-55110252 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.1" "Group enriched" "Detected in many" 24 "dendritic cells: 739.3;NK-cells: 1543.8;T-cells: 709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 15 "gdT-cell: 941.4;MAIT T-cell: 926.2;memory CD4 T-cell: 250.0;memory CD8 T-cell: 922.7;naive CD8 T-cell: 494.1;NK-cell: 718.8" "Group enriched" "Detected in all" 42 "NK-cells: 718.8;T-cells: 941.4" "Cell line enhanced" "Detected in some" "HL-60: 4.0;JURKAT: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054134, HPA076751" Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054134: AB_2682395, HPA076751: " "prognostic favorable (7.27e-4)" "unprognostic (7.29e-3)" "unprognostic (1.50e-2)" "prognostic favorable (6.44e-6)" "unprognostic (2.96e-3)" "unprognostic (1.85e-3)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.15e-3)" "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.26e-6)" "unprognostic (5.91e-2)" "unprognostic (5.57e-1)" "unprognostic (5.73e-3)" "unprognostic (3.33e-3)" 5.6 6.0 0.9 16.7 0.9 35.3 7.2 0.9 2.5 7.6 1.2 14.7 29.2 14.7 8.8 4.8 4.6 14.0 4.0 0.8 1.0 3.2 15.2 21.9 68.1 1.6 0.9 4.5 1.0 1.3 1.0 3.1 1.1 3.1 17.8 0.0 7.1 3.0 1.7 1.6 27.6 7.2 1.1 51.1 11.7 2.0 1.1 12.4 2.9 1.3 19.2 13.5 2.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 2.5 3.8 941.4 2.3 926.2 3.4 250.0 922.7 3.1 1.3 48.5 494.1 19.9 718.8 4.0 3.2 33.1 712.7 0.9 0.9 0.9 2.5 0.8 1.0 1.6 0.9 1.1 1.1 1.1 1.1 5.1 3.2 18.1 0.0 12.3 0.4 0.1 0.0 2.8 0.0 2.7 2.4 1.6 5.7 3.1 0.0 0.0 0.4 739.3 1.4 0.0 1.6 0.0 1.7 2.7 2.8 0.0 36.2 0.0 0.0 0.2 7.8 20.4 2.1 7.6 0.0 17.9 2.8 0.3 0.0 0.1 1.5 0.0 25.8 2.6 0.0 0.0 12.3 3.6 0.0 12.6 0.0 1543.8 0.0 0.1 0.0 3.9 0.0 40.8 0.1 2.8 3.3 2.9 0.0 0.0 2.6 2.6 0.0 0.1 1.1 1.4 0.7 709.4 0.0 1.8 0.0 GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.2;lymphoid tissue: 37.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2050.2;NK-cells: 1704.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 6765.2" "Lineage enriched" "Detected in all" 5 "dendritic cells: 6765.2" "Cell line enriched" "Detected in some" 6 "HMC-1: 22.0" "CAB000376, HPA003418" Enhanced "Secreted to blood" NA NA 2170 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB000376: AB_323716, HPA003418: AB_1079020" "prognostic favorable (7.27e-4)" "unprognostic (2.82e-3)" "unprognostic (8.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (2.07e-3)" "unprognostic (1.48e-3)" "unprognostic (4.43e-2)" "unprognostic (8.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.10e-7)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" 8.2 1.7 1.2 17.8 1.3 68.2 2.1 1.2 3.9 1.2 1.4 2.5 2.3 7.1 1.6 3.8 1.5 6.5 1.8 1.2 7.9 1.5 4.1 15.3 37.1 1.5 1.5 0.3 1.0 0.7 0.7 3.3 1.6 1.4 2.2 0.0 2.3 1.4 2.0 0.4 4.4 4.3 1.4 28.9 3.5 0.5 1.8 9.7 1.9 1.5 34.6 18.5 1.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.7 2.8 9.9 3.0 5.3 1338.5 4.0 16.0 7.0 95.2 641.6 6.3 3.1 29.1 607.5 43.1 507.8 6.0 6765.2 2.7 1607.1 1.2 1.3 1.2 3.9 1.2 7.9 1.5 1.5 1.6 1.4 1.8 1.3 4.3 6.4 36.0 0.0 15.9 2.8 0.3 0.0 0.0 0.0 0.9 0.8 1.1 4.3 7.4 0.0 0.0 0.4 2050.2 0.6 0.0 1.6 0.0 0.4 0.5 2.7 0.0 11.8 0.0 0.0 0.1 5.1 9.2 0.5 17.7 0.0 4.2 1.2 0.2 0.0 0.0 0.6 0.0 4.8 9.0 0.2 0.0 27.1 42.7 1.0 11.6 0.0 1704.4 0.0 0.1 0.1 2.3 0.0 86.8 0.2 0.6 3.1 4.4 0.0 0.0 1.3 1.3 0.0 0.1 0.4 4.1 0.3 373.8 0.0 0.6 0.1 GZMH "CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2" ENSG00000100450 "Granzyme H" P20718 14 24606480-24609699 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.9;lymphoid tissue: 25.2" "Group enriched" "Detected in many" 10 "dendritic cells: 575.2;NK-cells: 492.3;T-cells: 302.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 1678.5;memory CD4 T-cell: 490.7;memory CD8 T-cell: 1389.6;naive CD8 T-cell: 1214.0" "Lineage enriched" "Detected in all" 7 "T-cells: 1678.5" "Cell line enhanced" "Detected in single" "U-266/70: 1.0" "Low region specificity" "Detected in many" HPA029200 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA029200: AB_10602908" "unprognostic (3.72e-3)" "unprognostic (1.47e-3)" "unprognostic (5.35e-2)" "prognostic favorable (2.00e-6)" "unprognostic (8.80e-2)" "unprognostic (1.65e-3)" "unprognostic (2.08e-3)" "unprognostic (1.13e-1)" "unprognostic (1.62e-2)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.74e-6)" "unprognostic (1.23e-1)" "unprognostic (1.80e-1)" "unprognostic (3.35e-2)" "unprognostic (2.77e-3)" 3.4 5.2 1.2 3.1 1.3 33.9 4.6 1.3 2.4 2.6 1.6 2.7 2.4 2.0 5.0 3.6 3.5 7.0 2.5 1.1 1.3 1.2 6.7 15.9 25.2 2.0 1.2 2.8 0.8 0.7 2.4 1.6 1.5 1.4 2.5 0.0 7.9 2.1 1.9 0.6 2.8 3.4 1.3 24.4 4.7 0.8 1.4 3.8 1.5 0.6 4.5 7.5 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.2 31.6 3.4 1.7 1678.5 3.6 30.2 7.6 490.7 1389.6 3.3 4.6 155.1 1214.0 18.6 250.8 5.4 44.6 4.5 1436.5 1.2 1.3 1.3 2.4 1.1 1.3 2.0 1.2 1.5 1.3 1.4 1.3 2.9 0.0 4.6 0.0 3.3 1.1 0.1 0.0 0.0 0.0 1.7 1.5 1.4 8.6 0.0 0.0 0.0 0.1 575.2 0.0 0.0 0.1 0.1 0.3 0.3 1.5 0.0 8.6 0.0 0.0 0.0 1.2 1.1 0.4 1.3 0.0 7.5 1.2 0.1 0.0 0.0 0.0 0.0 9.3 3.4 0.2 0.0 4.5 3.6 1.9 3.1 0.0 492.3 0.0 0.1 0.0 0.0 0.0 43.7 0.2 0.0 2.6 0.7 0.0 0.0 1.9 1.3 0.1 0.0 0.4 1.8 0.0 302.2 0.0 0.1 0.1 GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024256-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 99.6" "Group enriched" "Detected in many" 4 "dendritic cells: 136.3;T-cells: 301.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 741.6;NK-cell: 505.5" "Group enriched" "Detected in many" 199 "NK-cells: 505.5;T-cells: 741.6" "Cell line enriched" "Detected in single" 10 "JURKAT: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA063181, HPA065895" Enhanced "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA063181: AB_2684955, HPA065895: " "prognostic favorable (8.68e-4)" "unprognostic (3.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-2)" "unprognostic (1.12e-3)" "unprognostic (1.03e-3)" "unprognostic (8.13e-3)" "unprognostic (3.50e-2)" "unprognostic (4.53e-2)" "unprognostic (9.74e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" 3.0 3.9 0.1 19.4 0.1 10.5 4.9 0.1 0.4 4.3 0.3 3.4 1.6 4.0 4.5 3.0 2.0 11.6 2.0 0.1 0.2 1.7 10.7 5.9 99.6 0.5 0.2 2.7 1.0 0.8 0.5 0.5 0.3 3.2 4.6 0.0 4.6 1.0 0.2 0.6 7.3 2.2 0.2 30.4 6.5 1.2 0.3 11.9 2.3 0.3 27.8 8.0 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.9 1.1 164.3 1.0 741.6 0.5 100.2 457.3 0.5 0.5 4.9 77.4 3.1 505.5 0.9 0.9 7.0 95.5 0.1 0.1 0.1 0.4 0.1 0.2 0.5 0.2 0.3 0.2 0.3 0.3 3.8 3.2 7.0 0.0 10.7 1.5 0.1 0.0 1.8 0.0 1.5 1.7 0.1 2.8 0.6 0.0 0.0 0.0 136.3 0.1 0.0 0.0 1.3 0.8 0.4 0.8 0.0 4.4 0.0 0.0 0.0 1.2 4.1 0.8 2.5 0.0 8.6 1.5 0.2 0.0 0.0 0.0 0.0 10.3 2.5 1.2 0.0 6.4 1.8 0.0 5.1 0.0 29.9 0.0 0.1 0.0 0.0 0.0 45.1 0.1 0.2 0.8 0.0 0.0 0.0 1.8 1.7 0.0 0.3 0.2 0.6 0.3 301.9 0.0 0.0 0.1 GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 22.7" "Group enriched" "Detected in many" 13 "dendritic cells: 385.8;NK-cells: 810.5;T-cells: 243.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 583.9" "Group enriched" "Detected in all" 33 "NK-cells: 194.9;T-cells: 583.9" "Cell line enhanced" "Detected in some" "EFO-21: 2.1;HDLM-2: 1.7;HMC-1: 2.1;JURKAT: 3.5;MOLT-4: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015624 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA015624: AB_2669245" "unprognostic (2.97e-3)" "unprognostic (2.29e-3)" "unprognostic (7.53e-2)" "prognostic favorable (1.89e-4)" "unprognostic (1.07e-1)" "prognostic favorable (1.87e-7)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.67e-1)" "unprognostic (4.98e-2)" "unprognostic (4.53e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.32e-1)" "unprognostic (9.51e-2)" "unprognostic (2.69e-3)" "unprognostic (9.94e-2)" 2.2 1.1 0.9 10.0 0.9 21.6 1.1 3.6 2.0 1.4 0.3 1.5 2.1 0.8 0.2 0.8 1.3 1.8 0.8 0.9 0.9 1.0 3.3 5.3 19.2 1.0 0.8 0.7 0.4 0.0 0.9 0.4 1.0 1.3 0.3 0.2 2.8 0.4 0.7 0.8 6.2 0.2 0.7 22.7 3.7 1.8 0.9 8.7 1.6 0.1 3.8 1.5 1.4 1.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.2 0.1 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.7 0.1 0.0 0.4 1.3 0.6 0.3 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.1 0.5 0.1 0.3 0.1 9.1 1.4 1.3 583.9 1.7 366.5 0.9 189.2 471.3 1.5 4.0 182.8 379.2 11.9 194.9 2.3 3.6 99.1 227.5 0.9 0.9 3.6 2.0 0.9 0.9 1.0 0.8 1.0 0.7 0.9 1.0 3.4 0.0 0.0 0.3 5.7 3.1 0.1 0.0 0.6 0.5 2.4 2.2 0.1 1.5 0.0 0.0 0.0 0.2 385.8 0.1 0.0 0.4 0.9 0.6 1.5 1.4 0.0 12.0 0.3 0.4 0.4 2.2 13.3 1.1 0.0 0.1 3.6 1.4 0.2 0.0 0.2 0.4 0.0 3.7 4.7 1.6 0.0 5.9 1.8 1.0 8.6 1.6 810.5 0.5 0.3 0.3 0.0 0.0 35.8 0.1 0.0 1.2 0.0 1.4 0.0 1.5 1.2 0.5 1.1 0.9 1.4 0.5 243.6 0.2 0.1 0.1 H6PD "GDH, H6PDH" ENSG00000049239 "Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase" O95479 1 9234774-9271337 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 94.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 164.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 68.9;ASC TERT1: 78.9;HSkMC: 77.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004824, HPA005440" Approved Uncertain Cytosol "Intracellular and membrane" NA NA 140000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA004824: AB_1079037, HPA005440: AB_1079036" "unprognostic (4.83e-3)" "unprognostic (3.91e-2)" "unprognostic (1.18e-1)" "unprognostic (3.49e-1)" "unprognostic (5.53e-3)" "unprognostic (2.86e-2)" "unprognostic (8.35e-2)" "unprognostic (5.18e-2)" "unprognostic (9.73e-2)" "unprognostic (1.26e-3)" "unprognostic (2.16e-2)" "unprognostic (7.35e-3)" "unprognostic (8.20e-2)" "unprognostic (3.61e-1)" "unprognostic (1.30e-1)" "unprognostic (8.65e-2)" "unprognostic (1.95e-1)" 29.0 30.5 7.5 12.6 11.6 9.7 23.0 8.2 9.0 22.6 18.8 15.1 11.2 25.7 14.4 13.5 28.3 12.6 18.9 6.4 7.8 11.5 94.5 20.3 12.4 14.4 10.8 44.9 18.9 10.6 12.7 14.1 11.4 19.5 9.1 4.2 56.2 13.1 48.3 35.7 16.8 16.6 9.6 14.5 18.7 8.1 11.4 13.1 14.7 21.0 11.4 16.7 16.5 10.9 9.9 8.0 6.8 25.5 68.9 78.9 6.4 9.8 24.0 7.1 10.9 1.5 20.1 10.9 11.2 15.3 9.1 10.3 1.8 4.8 10.3 32.8 2.2 0.0 2.8 6.7 38.6 3.5 4.1 77.7 9.1 17.2 11.1 15.6 32.9 5.9 2.9 18.2 14.0 5.7 3.9 8.2 3.7 7.5 4.6 1.2 0.9 9.3 9.1 4.0 2.3 12.0 12.9 10.0 12.0 4.7 7.5 17.4 32.9 24.3 3.9 6.2 2.8 24.1 7.6 2.5 40.8 15.6 15.7 1.6 2.3 0.3 1.6 2.4 1.3 1.3 1.2 1.5 1.0 1.6 1.2 1.1 1.5 1.2 2.3 1.4 1.1 1.5 7.5 11.6 8.2 9.0 6.4 7.8 14.4 10.8 11.4 9.6 11.4 10.9 24.1 25.6 29.5 17.9 10.1 14.3 13.2 16.9 18.8 19.6 10.3 8.3 17.5 58.6 18.8 20.2 27.1 11.2 9.1 16.6 0.0 22.9 0.8 11.2 36.0 19.8 7.8 9.0 8.4 21.3 8.5 33.6 5.6 15.5 3.8 29.9 19.6 164.0 12.1 16.8 9.1 15.1 8.2 25.4 11.4 2.9 48.1 14.2 12.4 13.1 51.6 10.4 19.6 16.6 18.6 20.0 17.0 36.9 4.5 17.2 23.1 7.4 19.1 10.9 0.0 50.5 11.7 4.6 5.5 10.5 12.8 5.9 11.6 26.1 23.6 14.2 HABP2 "FSAP, HABP, HGFAL, PHBP" ENSG00000148702 "Hyaluronan binding protein 2" Q14520 10 113550837-113589602 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 437.3" "Group enriched" "Detected in some" 5 "Cholangiocytes: 124.4;Hepatocytes: 221.4" "Cancer enriched" "Detected in many" 5 "liver cancer: 92.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "OE19: 64.7;RPTEC TERT1: 50.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA019518 Uncertain "Secreted to blood" NA NA 20200000000 4400000000 "Cluster 62: Liver - Hemostasis" "Cluster 21: OE19 - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" "HPA019518: AB_1850467" "unprognostic (3.89e-2)" "unprognostic (6.15e-2)" "unprognostic (1.33e-1)" "unprognostic (1.24e-1)" "unprognostic (1.45e-1)" "unprognostic (6.92e-2)" "unprognostic (1.01e-1)" "unprognostic (5.86e-3)" "unprognostic (1.67e-1)" "unprognostic (9.78e-2)" "unprognostic (5.10e-2)" "unprognostic (4.77e-2)" "unprognostic (9.18e-3)" "unprognostic (2.62e-3)" "unprognostic (2.11e-1)" "unprognostic (3.22e-1)" "unprognostic (9.05e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.9 0.9 0.0 0.0 3.1 2.9 1.7 0.0 2.2 36.0 3.8 0.1 0.0 14.2 437.3 0.8 0.0 0.0 0.0 0.0 17.3 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.1 12.1 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 64.7 0.0 0.0 0.1 0.0 50.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 2.3 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 124.4 0.0 1.8 0.0 0.0 0.0 0.0 3.9 31.4 0.5 10.8 0.8 0.4 0.0 5.3 1.0 3.9 0.0 0.0 17.9 6.5 0.0 0.0 5.3 221.4 1.0 0.0 0.0 0.2 0.0 5.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 12.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.1 HACD1 "CAP, PTPLA" ENSG00000165996 "3-hydroxyacyl-CoA dehydratase 1" B0YJ81 10 17589032-17617374 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Developmental protein, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.0" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 143.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "T-reg: 55.7" "Lineage enriched" "Detected in many" 12 "T-cells: 55.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (3.54e-1)" "unprognostic (2.62e-2)" "unprognostic (4.10e-1)" "unprognostic (5.67e-3)" "unprognostic (4.21e-2)" "unprognostic (3.04e-2)" "unprognostic (2.38e-1)" "unprognostic (1.70e-2)" "unprognostic (2.61e-2)" "unprognostic (3.43e-1)" "unprognostic (2.46e-2)" "unprognostic (2.93e-2)" "unprognostic (3.40e-2)" "unprognostic (1.10e-1)" "unprognostic (6.49e-2)" 9.7 7.0 3.1 5.0 3.5 8.0 8.8 10.7 4.6 6.8 2.9 31.9 2.8 22.1 3.3 7.8 10.3 3.6 73.0 3.0 6.5 5.0 1.6 9.7 1.3 5.5 5.2 4.3 2.7 0.5 3.7 1.6 5.0 11.9 3.8 2.3 2.7 16.7 36.5 3.0 6.9 25.4 2.4 1.7 15.0 3.5 4.7 2.6 7.6 16.5 1.2 18.1 6.8 8.4 29.3 24.6 6.8 33.4 30.1 5.8 0.6 40.5 24.4 51.9 48.5 16.4 34.6 0.2 5.9 66.4 74.5 7.1 17.3 12.3 28.6 19.1 10.4 67.1 18.4 45.6 39.0 0.3 4.8 14.0 17.2 29.9 11.6 39.8 10.1 35.1 0.6 1.3 69.0 21.0 50.4 6.7 14.6 2.2 6.6 44.7 7.1 0.8 20.5 5.6 7.5 19.1 34.6 0.6 58.9 21.2 24.2 16.7 9.8 30.3 17.4 18.7 18.8 0.9 0.8 0.3 22.3 7.7 4.3 4.7 0.9 0.7 1.2 0.1 0.3 0.4 5.0 1.0 3.0 1.3 0.9 0.7 2.6 3.3 0.3 1.5 55.7 1.3 3.1 3.5 10.7 4.6 3.0 6.5 5.5 5.2 5.0 2.4 4.7 8.4 2.4 28.9 15.0 0.3 0.4 0.0 23.1 0.0 8.0 0.8 6.9 21.6 143.7 10.0 2.5 31.3 0.0 0.5 4.4 0.4 3.9 16.5 11.1 5.6 8.0 5.4 3.6 29.2 10.4 8.0 1.9 7.1 8.2 12.4 6.3 17.5 20.7 1.0 5.4 0.0 11.7 2.5 0.0 2.2 0.0 2.7 1.8 3.6 0.0 5.6 0.8 0.5 1.0 2.5 31.8 15.6 0.8 0.7 0.6 23.9 0.5 2.3 0.7 0.6 0.0 5.7 32.5 7.4 5.2 17.7 0.0 3.0 2.9 10.8 3.5 6.2 HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290465 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 793.3;skeletal muscle: 950.6;tongue: 1097.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1167.5;Distal tubular cells: 520.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037539, HPA037540, HPA066099" Enhanced Supported Mitochondria No No 61000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA037539: AB_10671374, HPA037540: AB_2675531, HPA066099: AB_2685618" "unprognostic (5.15e-2)" "unprognostic (8.72e-2)" "unprognostic (8.21e-2)" "unprognostic (8.67e-2)" "unprognostic (7.70e-2)" "unprognostic (2.59e-2)" "unprognostic (7.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (2.03e-1)" "unprognostic (8.94e-2)" "prognostic favorable (1.37e-9)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (2.88e-1)" "unprognostic (9.68e-2)" 127.0 224.7 120.6 51.1 135.4 58.8 91.3 146.4 138.1 65.2 128.0 110.7 224.2 55.9 73.7 101.3 68.8 64.3 793.3 109.0 138.1 231.4 324.8 64.7 54.9 135.9 141.6 78.4 83.7 209.5 48.1 65.6 139.6 77.1 113.2 63.0 104.8 75.0 950.6 74.4 184.4 79.0 141.4 75.8 109.0 67.1 143.3 53.1 90.8 1097.1 62.5 89.2 64.1 152.8 108.2 83.2 56.6 102.2 342.1 190.1 57.9 89.0 134.6 89.0 86.8 100.5 101.7 53.9 60.8 145.3 100.1 82.8 95.2 124.8 109.2 121.1 83.1 123.6 44.9 194.2 145.9 100.6 90.0 183.7 201.6 92.7 149.0 151.0 168.2 81.0 105.2 83.9 189.5 78.0 57.1 190.7 39.8 160.2 89.0 61.7 188.3 103.2 183.3 148.9 27.2 93.7 151.7 169.8 239.5 68.5 105.4 177.9 118.0 83.5 86.9 79.3 65.1 62.6 101.1 94.7 95.5 158.4 84.4 95.7 168.1 66.4 45.2 150.3 57.6 65.5 61.3 56.6 154.2 49.7 55.8 51.3 72.7 88.2 123.3 51.8 94.7 135.6 120.6 135.4 146.4 138.1 109.0 138.1 135.9 141.6 139.6 141.4 143.3 152.8 106.5 48.1 36.5 63.0 48.3 62.1 136.5 183.3 49.5 29.3 49.5 52.3 1167.5 104.4 107.7 97.5 56.3 227.9 42.4 129.5 520.4 124.0 93.4 59.5 49.0 75.2 74.9 85.2 32.7 57.2 75.2 79.5 53.0 60.2 62.8 94.2 69.9 277.6 139.6 13.5 33.0 93.4 114.0 98.1 67.4 99.7 56.5 78.1 88.9 27.2 110.2 65.0 32.0 35.2 47.5 58.4 134.8 62.8 37.1 60.5 376.0 321.1 73.5 80.0 72.3 72.9 80.7 120.4 49.4 53.8 54.7 186.6 45.2 194.0 113.5 110.3 HAMP "HEPC, HFE2B, LEAP-1, LEAP1" ENSG00000105697 "Hepcidin antimicrobial peptide" P81172 19 35280716-35285143 "Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide, Hormone" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2054.8" "Cell type enriched" "Detected in many" 17 "Hepatocytes: 3227.7" "Group enriched" "Detected in many" 12 "glioma: 6.5;liver cancer: 16.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "myeloid DC: 1.5;plasmacytoid DC: 4.6" "Lineage enriched" "Detected in single" 10 "dendritic cells: 4.6" "Cell line enriched" "Detected in some" 440 "Hep G2: 448.0" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 1900000 10000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (5.53e-2)" "unprognostic (5.02e-4)" "unprognostic (2.10e-3)" "unprognostic (4.69e-3)" "unprognostic (5.35e-2)" "unprognostic (2.24e-1)" "unprognostic (3.92e-2)" "unprognostic (9.36e-2)" "unprognostic (2.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.61e-1)" "unprognostic (1.86e-1)" "unprognostic (3.68e-7)" "unprognostic (4.11e-2)" "unprognostic (3.93e-2)" "unprognostic (4.08e-2)" "unprognostic (7.77e-2)" 1.0 1.2 17.7 2.0 17.6 5.4 1.5 17.4 30.4 2.3 20.8 0.8 0.9 0.3 0.6 0.5 2.8 0.6 415.0 17.8 20.2 1.1 2054.8 3.2 4.0 48.0 24.9 3.2 88.0 0.4 5.8 2.3 25.8 2.7 0.0 4.2 1.2 1.3 1.2 1.1 0.5 1.0 21.5 1.1 1.1 0.7 18.7 0.1 0.4 0.2 4.4 1.6 0.2 21.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.7 448.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.7 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.4 0.0 4.6 0.0 0.0 17.7 17.6 17.4 30.4 17.8 20.2 48.0 24.9 25.8 21.5 18.7 21.0 0.8 0.0 0.0 0.0 5.7 0.5 1.5 0.0 0.0 0.0 26.2 8.0 1.7 30.0 0.6 0.0 0.0 0.9 0.6 0.1 0.0 0.4 0.0 1.9 1.0 13.7 0.0 89.7 0.2 99.0 1.2 0.4 10.7 1.8 75.7 0.7 45.3 3227.7 187.9 0.0 0.0 0.7 0.0 63.2 1.2 0.0 0.0 28.4 0.0 0.0 0.0 0.6 0.0 0.0 0.1 22.6 0.1 0.0 0.1 4.2 0.0 0.1 0.0 0.6 0.0 0.2 0.6 0.0 0.0 0.0 18.6 0.7 4.3 0.5 0.2 2.2 HAPLN1 CRTL1 ENSG00000145681 "Hyaluronan and proteoglycan link protein 1" P10915 5 83637805-83720855 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "placenta: 75.0" "Cell type enhanced" "Detected in some" "Fibroblasts: 146.7;Granulosa cells: 43.2;Inhibitory neurons: 35.6;Syncytiotrophoblasts: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "PC-3: 152.4;SuSa: 70.1;TIME: 91.8;U-2 OS: 139.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019105, HPA019482, HPA025238" Enhanced Approved Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA019105: AB_1850496, HPA019482: AB_1850498, HPA025238: " "unprognostic (5.74e-4)" "unprognostic (2.94e-2)" "unprognostic (6.58e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (2.76e-3)" "unprognostic (6.01e-4)" "unprognostic (2.52e-2)" "unprognostic (1.70e-1)" "unprognostic (9.04e-3)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "prognostic unfavorable (4.81e-9)" "unprognostic (6.87e-2)" "unprognostic (2.04e-1)" "unprognostic (8.62e-2)" "unprognostic (3.91e-2)" 0.1 0.0 0.3 0.8 0.7 0.0 0.1 1.1 0.9 0.1 0.0 9.0 7.2 0.6 0.3 2.1 0.0 0.8 3.9 0.6 2.7 0.1 0.0 0.5 0.0 0.9 1.0 0.5 0.5 0.2 0.0 75.0 0.6 0.9 11.1 0.1 0.5 0.0 0.0 0.3 10.8 0.5 0.3 0.2 4.8 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 2.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.2 0.0 3.4 0.0 152.4 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 70.1 0.1 0.0 91.8 0.0 139.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 1.1 0.9 0.6 2.7 0.9 1.0 0.6 0.3 0.0 0.3 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.2 0.0 0.2 0.0 0.0 0.0 0.1 0.5 6.9 0.0 0.0 0.5 0.0 10.6 146.7 0.0 0.1 0.0 43.2 0.0 0.0 10.6 0.0 35.6 2.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 23.7 0.1 3.8 0.4 0.0 HAPLN2 BRAL1 ENSG00000132702 "Hyaluronan and proteoglycan link protein 2" Q9GZV7 1 156619331-156625725 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 270.8" "Cell type enriched" "Detected in some" 6 "Oligodendrocytes: 202.1" "Cancer enriched" "Detected in some" 10 "glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045765 Enhanced "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA045765: AB_10964781" "unprognostic (3.19e-3)" "unprognostic (1.06e-1)" "unprognostic (1.02e-2)" "unprognostic (3.41e-1)" "unprognostic (1.88e-1)" "unprognostic (2.44e-1)" "unprognostic (1.92e-1)" "unprognostic (2.04e-3)" "unprognostic (1.31e-1)" "unprognostic (8.25e-2)" "unprognostic (5.54e-3)" "unprognostic (2.72e-2)" "unprognostic (2.70e-2)" "unprognostic (1.08e-1)" "unprognostic (2.25e-1)" "unprognostic (1.05e-1)" "unprognostic (4.17e-3)" 0.7 0.3 52.0 0.0 147.5 0.0 0.5 179.7 74.3 0.8 16.4 0.5 0.8 2.7 0.0 0.1 2.6 0.0 1.7 51.3 84.9 0.5 0.1 0.3 0.0 270.8 149.6 0.6 0.1 0.2 0.4 0.0 215.0 2.5 0.0 0.1 0.2 0.1 0.7 0.3 0.7 0.0 141.7 0.1 0.3 1.3 132.9 0.0 0.3 0.1 0.0 1.3 1.0 255.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.0 147.5 179.7 74.3 51.3 84.9 270.8 149.6 215.0 141.7 132.9 255.2 1.5 0.0 0.0 5.2 0.0 0.1 0.1 0.0 0.0 1.7 0.9 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.4 2.3 0.0 0.0 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.7 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 12.5 202.1 0.0 5.0 0.0 0.0 0.2 2.8 0.0 0.0 0.5 32.9 0.9 14.4 0.7 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 HAPLN3 "EXLD1, HsT19883" ENSG00000140511 "Hyaluronan and proteoglycan link protein 3" Q96S86 15 88877294-88895597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 966.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 50.9" "Lineage enriched" "Detected in all" 5 "T-cells: 50.9" "Cell line enhanced" "Detected in many" "HDLM-2: 34.7;U-2 OS: 31.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039237 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 9: U-2 OS - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA039237: AB_10805357" "unprognostic (1.67e-2)" "unprognostic (1.04e-3)" "unprognostic (2.57e-1)" "unprognostic (2.53e-2)" "unprognostic (3.27e-1)" "unprognostic (2.24e-2)" "unprognostic (4.21e-1)" "unprognostic (3.82e-1)" "unprognostic (3.37e-3)" "unprognostic (7.37e-3)" "unprognostic (1.13e-3)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.18e-13)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.12e-1)" 10.3 1.9 2.1 11.5 2.0 3.1 8.6 1.9 2.7 5.1 2.1 3.2 0.6 4.3 0.1 6.1 6.2 2.7 4.6 2.1 2.0 6.1 0.9 9.7 11.7 2.4 2.1 2.7 1.4 0.5 2.2 1.4 2.5 5.7 0.4 4.2 6.0 0.7 3.6 6.2 4.6 2.7 2.3 5.7 3.5 1.0 2.4 2.9 4.6 0.6 3.2 6.9 5.6 2.1 2.0 7.0 1.3 15.4 4.4 4.2 4.7 4.4 1.0 1.6 2.0 4.4 6.4 0.0 11.9 5.4 2.5 1.7 14.7 1.9 0.0 34.7 12.9 4.9 0.3 0.0 0.6 0.0 0.1 1.6 0.8 3.0 0.2 0.2 7.1 0.6 0.1 9.3 0.8 0.2 0.1 0.0 11.2 0.0 0.2 0.0 0.6 11.5 2.9 0.1 0.1 4.2 0.9 0.7 6.1 1.9 0.0 0.6 1.3 10.8 31.2 8.1 0.7 1.1 0.1 0.1 3.8 0.0 9.3 1.4 1.1 0.0 1.2 0.8 5.4 0.2 18.3 7.4 2.2 1.5 18.3 8.6 0.3 10.1 0.2 0.8 50.9 5.9 2.1 2.0 1.9 2.7 2.1 2.0 2.4 2.1 2.5 2.3 2.4 2.1 16.0 0.0 3.4 1.3 4.0 32.0 10.8 13.5 4.6 2.5 47.1 42.4 9.3 1.5 10.4 1.8 10.4 5.8 3.2 0.5 0.0 5.3 0.0 6.3 3.7 29.4 0.0 0.0 1.3 2.0 966.2 8.5 1.5 12.1 1.3 2.5 3.3 0.1 19.3 0.0 0.1 0.9 6.1 0.3 22.0 0.2 0.9 3.0 17.8 2.8 9.7 3.8 3.1 0.5 0.1 9.9 0.1 0.7 0.5 10.4 0.0 0.2 2.7 103.8 13.1 7.2 24.5 0.3 2.1 6.3 24.2 20.4 9.4 0.2 0.5 7.8 HAPLN4 "BRAL2, KIAA1926" ENSG00000187664 "Hyaluronan and proteoglycan link protein 4" Q86UW8 19 19254756-19262804 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 107.1" "Group enriched" "Detected in some" 7 "Excitatory neurons: 16.0;Hepatocytes: 6.7;Inhibitory neurons: 19.9;Proximal enterocytes: 15.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 3.5;NTERA-2: 8.3;SCLC-21H: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055856 Enhanced "Secreted in brain" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA055856: AB_2682946" "unprognostic (3.36e-4)" 0.1 1.0 5.8 0.1 3.7 0.2 0.2 18.3 107.1 2.0 0.0 0.2 12.4 0.8 0.1 0.0 0.2 0.2 0.1 10.7 20.0 0.5 14.1 0.1 0.1 46.6 9.7 0.6 0.9 0.0 0.7 0.2 43.2 0.6 0.1 2.3 0.1 0.3 0.0 0.2 15.4 0.2 10.9 0.1 0.3 0.1 33.6 0.0 0.0 0.0 0.0 0.1 0.5 35.6 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.3 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 3.5 8.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 1.0 0.0 0.1 0.0 0.4 0.1 0.7 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 3.7 18.3 107.1 10.7 20.0 46.6 9.7 43.2 10.9 33.6 35.6 0.1 0.0 0.0 2.0 0.1 0.1 0.0 0.0 0.0 0.7 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.1 0.0 0.0 16.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.4 6.7 0.1 0.0 19.9 0.6 0.0 0.0 0.0 0.2 0.3 0.1 0.0 1.0 0.0 0.2 0.0 0.5 1.6 0.0 0.0 0.0 0.0 0.0 15.0 0.2 0.0 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 HAVCR1 "CD365, HAVCR, HAVCR-1, KIM1, TIM-1, TIM1, TIMD1" ENSG00000113249 "Hepatitis A virus cellular receptor 1" Q96D42 5 157029413-157059119 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 4.6;kidney: 7.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.9;Inhibitory neurons: 1.3;Microglial cells: 5.6;Oligodendrocytes: 1.8;Proximal tubular cells: 2.3" "Cancer enriched" "Detected in many" 12 "renal cancer: 26.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 93.0;CACO-2: 113.9;RPTEC TERT1: 43.5" "Low region specificity" "Detected in many" "HPA007173, CAB075697" Uncertain Approved Vesicles NA NA 155000 "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "CAB075697: , HPA007173: AB_1080282" "unprognostic (1.24e-1)" "unprognostic (1.66e-1)" "unprognostic (5.76e-2)" "unprognostic (2.00e-1)" "unprognostic (6.99e-2)" "unprognostic (2.46e-3)" "unprognostic (4.75e-3)" "unprognostic (3.20e-2)" "unprognostic (3.21e-1)" "unprognostic (8.70e-4)" "unprognostic (3.81e-3)" "unprognostic (7.10e-3)" "prognostic unfavorable (7.81e-4)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "prognostic favorable (1.32e-4)" 0.3 0.0 0.3 0.4 0.3 0.9 0.1 0.6 0.4 0.1 0.5 4.6 0.2 0.1 0.2 0.0 0.1 0.5 0.0 0.4 0.3 7.5 0.3 0.3 0.6 0.7 0.4 0.1 0.0 0.1 0.0 0.1 0.5 0.0 3.5 0.3 0.1 0.0 0.0 0.2 0.1 0.2 0.3 0.3 0.3 0.9 0.5 0.1 0.1 0.0 0.3 0.1 0.0 0.8 0.0 93.0 0.2 0.0 0.3 0.0 13.8 0.0 0.0 0.0 0.0 113.9 0.0 0.0 14.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 43.5 3.4 0.2 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.0 0.5 0.2 0.1 0.1 0.1 0.2 0.2 0.3 0.1 0.1 0.2 0.6 0.5 0.2 0.4 0.1 0.1 0.6 0.4 0.3 0.3 0.6 0.4 0.4 0.3 0.7 0.4 0.5 0.3 0.5 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.9 0.0 0.1 0.0 5.6 0.0 0.0 0.0 1.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.1 0.0 HCCS "CCHL, MLS" ENSG00000004961 "Holocytochrome c synthase" P53701 X 11111301-11123086 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002946 Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "HPA002946: AB_1079041" "prognostic unfavorable (8.69e-5)" "unprognostic (6.89e-3)" "unprognostic (8.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.34e-1)" "unprognostic (5.44e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (9.18e-2)" "unprognostic (2.73e-1)" "unprognostic (2.52e-2)" "unprognostic (2.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (6.17e-8)" "unprognostic (2.66e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.93e-2)" 13.9 16.1 6.2 13.7 6.7 20.5 12.6 7.0 8.4 8.4 8.4 21.6 23.1 9.6 7.6 19.3 8.5 10.8 39.0 7.4 6.8 17.6 22.9 11.5 15.6 6.7 6.2 8.3 9.9 25.1 8.3 13.1 6.4 9.5 21.6 13.5 15.2 10.0 64.4 17.6 20.2 12.5 6.2 14.5 15.3 10.2 6.7 13.0 10.8 57.0 17.1 22.3 11.6 6.1 54.3 60.5 31.8 28.5 25.6 25.2 29.2 52.0 43.0 67.8 57.5 70.7 38.5 34.3 26.3 46.1 80.8 49.8 63.2 51.8 70.5 30.8 48.0 34.1 80.8 38.6 47.3 40.9 39.4 24.2 37.4 67.9 46.5 37.9 49.1 26.1 63.1 41.1 46.3 72.5 28.0 31.4 51.5 36.6 70.1 27.3 59.9 65.4 44.0 44.8 20.9 24.2 54.8 58.7 38.2 66.7 45.6 27.1 48.7 42.4 23.6 110.4 47.0 26.9 29.0 47.8 35.5 28.8 42.7 25.6 47.8 30.1 20.2 66.4 19.0 39.0 19.6 18.2 62.2 34.7 17.1 22.1 13.1 19.1 57.4 56.2 23.5 19.0 6.2 6.7 7.0 8.4 7.4 6.8 6.7 6.2 6.4 6.2 6.7 6.1 15.5 6.4 4.8 2.3 20.8 54.8 53.2 57.0 22.8 5.3 16.1 13.7 49.3 17.2 33.3 16.5 0.0 32.9 12.4 44.6 50.9 34.9 13.7 19.0 10.4 21.0 10.8 32.8 3.8 29.3 37.9 17.1 12.8 16.7 13.3 10.4 15.7 18.5 41.8 8.4 4.5 19.2 67.1 21.0 44.1 2.3 13.4 23.5 24.9 1.9 27.9 13.0 7.2 2.0 2.7 68.4 31.9 10.5 18.4 63.5 46.4 36.0 28.9 7.1 6.6 12.5 20.1 24.4 28.4 21.8 46.0 40.9 12.0 15.6 30.2 88.6 HCFC1 "CFF, HCF-1, HCF1, HFC1, MGC70925, MRX3, PPP1R89, VCAF" ENSG00000172534 "Host cell factor C1" P51610 X 153947557-153971818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction" "Chromatin regulator" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078588 Supported Supported Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA078588: " "unprognostic (2.05e-3)" "unprognostic (2.92e-2)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (2.64e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (4.31e-6)" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "prognostic favorable (9.62e-5)" "unprognostic (1.45e-1)" "unprognostic (1.29e-3)" "unprognostic (1.99e-2)" "unprognostic (2.12e-1)" "unprognostic (1.73e-2)" "unprognostic (2.80e-1)" 18.8 25.5 18.4 15.5 16.9 40.2 17.1 14.9 22.5 21.9 10.3 29.7 11.4 33.6 8.5 25.1 24.3 7.6 23.1 19.7 14.1 22.1 23.8 21.6 19.0 16.6 16.8 25.5 21.1 11.4 33.9 8.7 15.2 23.5 7.0 7.2 19.2 12.8 28.4 18.6 25.3 11.1 13.6 32.8 24.8 17.9 16.8 26.1 21.1 10.5 12.1 23.6 19.8 17.1 45.3 57.7 38.4 48.9 15.8 11.2 56.3 18.2 14.0 21.1 19.1 61.5 29.8 81.6 45.3 23.6 34.6 36.4 41.8 29.7 11.0 43.6 49.2 49.0 47.7 48.8 10.8 60.9 77.8 17.6 19.1 36.8 15.9 12.7 22.7 58.2 69.4 50.2 15.0 63.0 84.6 78.2 50.0 29.4 35.1 97.5 31.6 49.3 16.0 41.4 42.5 46.2 33.7 34.4 19.4 18.4 31.7 54.4 30.2 39.9 49.0 35.0 59.4 79.1 117.0 100.2 32.5 58.6 38.6 0.9 2.1 0.9 3.0 3.1 2.1 2.4 2.4 2.3 2.4 2.4 2.4 3.4 0.4 1.5 2.2 4.2 1.7 2.3 18.4 16.9 14.9 22.5 19.7 14.1 16.6 16.8 15.2 13.6 16.8 17.1 19.1 19.2 17.8 7.5 21.9 16.6 13.4 15.5 20.5 21.0 24.6 18.7 35.9 20.0 13.6 12.9 14.6 16.5 26.8 20.1 3.9 17.4 0.6 16.7 18.4 21.2 19.2 39.9 8.4 16.5 21.3 17.7 19.9 21.6 3.8 25.0 15.7 29.5 21.3 20.2 8.3 23.2 8.2 35.2 13.8 1.8 17.4 26.0 5.4 9.4 28.6 13.6 17.5 8.0 7.2 19.5 13.3 21.8 32.0 25.7 12.6 8.8 13.4 12.4 6.6 21.8 21.2 11.3 25.0 28.9 13.9 15.9 22.8 14.3 23.9 20.5 HCRT "OX, PPOX" ENSG00000161610 "Hypocretin neuropeptide precursor" O43612 17 42184060-42185452 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neuropeptide "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1067 "brain: 384.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Enteroendocrine cells: 3.0;Kupffer cells: 1.6;Oligodendrocyte precursor cells: 2.0;Proximal enterocytes: 1.6" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Region enriched" "Detected in many" 7 "hypothalamus: 384.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "hypothalamus: 93.5" "Region enriched" "Detected in some" 21 "hypothalamus: 25.3" "HPA064801, CAB079778" Enhanced Supported "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 58: T-cells - T-cell receptor" "CAB079778: , HPA064801: " "unprognostic (3.34e-2)" "unprognostic (7.76e-5)" "unprognostic (3.21e-2)" "unprognostic (3.01e-2)" "unprognostic (2.20e-2)" "unprognostic (1.41e-1)" "unprognostic (1.23e-1)" 0.1 0.0 1.8 0.1 1.9 0.1 0.0 0.6 1.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 384.8 0.0 0.0 0.0 0.0 0.6 3.1 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 0.1 0.5 0.3 0.2 0.3 0.1 0.6 0.3 0.3 0.0 0.1 0.0 0.0 0.1 0.0 1.8 1.9 0.6 1.2 0.5 384.8 0.6 3.1 1.7 0.3 52.6 0.6 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.0 1.8 0.0 0.0 1.2 0.3 0.0 0.0 0.0 0.5 0.1 0.1 3.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.7 0.2 0.6 0.0 0.4 0.8 0.0 1.6 1.0 0.2 0.0 0.3 0.0 1.0 0.8 0.1 0.0 2.0 0.3 0.4 0.1 0.0 0.4 0.0 1.6 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.9 0.1 0.9 0.1 HDAC6 "FLJ16239, HD6, JM21, KIAA0901, PPP1R90" ENSG00000094631 "Histone deacetylase 6" Q9UBN7 X 48801377-48824982 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" "Actin-binding, Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003714, CAB004236, HPA026321" Supported Supported Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB004236: AB_627708, HPA003714: AB_1850544, HPA026321: AB_1850546" "unprognostic (9.53e-2)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (2.42e-2)" "unprognostic (2.82e-2)" "unprognostic (4.11e-3)" "unprognostic (2.17e-2)" "unprognostic (1.16e-1)" "unprognostic (7.68e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-3)" "unprognostic (2.33e-2)" "unprognostic (6.10e-2)" "unprognostic (1.47e-1)" "unprognostic (6.60e-2)" "unprognostic (2.34e-1)" "prognostic favorable (3.34e-4)" 21.9 26.0 26.6 14.2 30.7 22.9 23.6 31.1 54.2 29.6 29.8 27.8 17.8 26.8 10.6 24.4 28.2 11.1 26.0 26.7 33.0 57.9 97.3 25.2 15.6 32.6 32.7 32.5 26.3 22.3 45.6 13.8 33.9 24.4 16.1 27.9 21.6 12.2 26.1 21.4 28.0 15.3 28.9 29.4 26.6 53.8 30.6 18.8 27.1 16.1 15.1 23.7 22.8 31.0 31.0 25.7 49.6 19.1 20.2 16.6 33.4 14.4 12.4 27.2 26.2 24.9 25.7 29.9 13.8 17.1 34.6 21.3 30.6 15.5 23.2 27.7 19.1 40.7 32.2 26.0 18.3 19.2 60.4 25.7 25.1 21.5 25.3 24.8 23.5 37.4 45.9 31.9 17.7 10.9 27.0 29.3 18.5 14.2 24.5 23.1 53.5 31.3 15.8 13.3 25.9 25.3 29.5 8.7 17.4 63.4 36.1 17.5 19.1 21.5 26.7 29.3 14.2 29.6 31.3 21.3 21.3 24.0 21.5 0.0 5.1 5.8 4.7 8.3 3.4 3.7 3.3 3.4 7.6 5.3 3.1 2.9 2.5 3.6 11.7 8.3 4.0 4.9 26.6 30.7 31.1 54.2 26.7 33.0 32.6 32.7 33.9 28.9 30.6 31.0 11.4 19.2 25.1 20.9 12.5 7.5 10.2 8.8 6.2 37.6 10.7 10.4 10.6 8.6 17.5 18.4 50.1 11.5 12.6 21.4 19.6 7.9 48.1 10.0 13.0 10.3 14.4 11.4 15.2 7.4 12.3 10.7 21.9 13.2 6.3 22.5 13.6 51.9 11.1 40.4 18.4 15.5 10.2 12.3 9.8 18.4 14.0 13.2 5.4 10.3 12.7 21.9 18.6 17.1 19.0 7.2 13.2 11.3 12.8 7.1 17.8 47.6 12.4 34.0 13.1 15.5 11.1 88.4 41.7 8.6 5.8 9.7 9.7 21.8 16.2 7.2 HDHD5 CECR5 ENSG00000069998 "Haloacid dehalogenase like hydrolase domain containing 5" Q9BXW7 22 17137511-17165287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 43.0;Ductal cells: 35.2;Extravillous trophoblasts: 42.2;Granulosa cells: 37.0;Hofbauer cells: 42.3;Proximal tubular cells: 41.1;Theca cells: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005548 Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA005548: AB_1078497" "unprognostic (4.04e-2)" "unprognostic (5.04e-2)" "unprognostic (4.54e-3)" "unprognostic (6.61e-2)" "unprognostic (1.20e-1)" "unprognostic (5.71e-2)" "unprognostic (1.04e-3)" "unprognostic (7.35e-2)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (5.76e-2)" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (7.07e-3)" "unprognostic (1.71e-1)" "unprognostic (1.20e-2)" "unprognostic (7.21e-3)" 17.4 29.7 15.0 13.2 15.3 16.5 17.3 15.4 15.7 12.9 16.7 21.5 26.5 14.6 6.8 21.7 13.6 9.8 45.0 15.4 14.8 19.8 40.5 12.6 14.5 15.4 14.9 12.2 20.9 17.5 11.6 8.1 14.6 15.5 14.1 5.7 18.6 10.0 46.9 23.0 17.2 11.4 14.8 19.3 19.9 15.9 15.9 13.6 10.1 55.7 12.0 16.5 14.1 15.0 64.0 41.5 30.5 41.5 17.7 10.8 38.8 17.9 19.6 47.1 50.2 61.1 23.3 103.9 29.3 21.6 23.0 44.0 38.7 42.0 21.8 31.6 56.7 0.0 30.7 0.0 29.4 47.6 23.5 26.1 51.1 21.0 23.1 26.4 33.3 67.4 31.0 26.2 24.9 62.1 84.2 97.2 46.6 97.9 36.7 47.4 45.8 26.3 32.2 34.7 61.4 46.5 34.9 49.9 54.3 23.9 50.1 58.5 29.1 39.7 29.4 28.2 31.3 41.3 48.5 77.8 32.0 0.1 34.2 12.3 86.2 4.7 28.4 56.7 35.6 24.6 26.4 25.8 74.5 23.6 34.3 29.3 4.5 30.7 31.4 30.9 29.7 48.0 15.0 15.3 15.4 15.7 15.4 14.8 15.4 14.9 14.6 14.8 15.9 15.0 21.5 6.4 2.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 23.9 22.4 0.0 0.0 5.0 5.5 0.0 26.5 9.3 0.0 43.0 35.2 0.0 8.4 14.9 9.2 0.0 0.0 0.0 28.2 42.2 7.7 0.0 11.5 5.1 37.0 0.0 0.0 42.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 5.2 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.5 0.0 0.0 41.1 1.5 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 15.7 3.4 55.8 0.0 0.0 HDLBP "HBP, VGL" ENSG00000115677 "High density lipoprotein binding protein" Q00341 2 241227264-241317061 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004189, CAB026457" Enhanced Supported Cytosol NA NA 95000 "Cluster 14: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB026457: , HPA004189: AB_1079044" "unprognostic (2.57e-2)" "unprognostic (1.13e-2)" "unprognostic (2.13e-2)" "unprognostic (1.51e-1)" "unprognostic (4.46e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.58e-5)" "unprognostic (1.70e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-2)" "unprognostic (4.39e-3)" "unprognostic (3.92e-2)" "unprognostic (9.48e-3)" "unprognostic (2.47e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (6.39e-5)" "prognostic unfavorable (4.12e-4)" 159.7 135.7 54.9 114.0 62.4 105.4 150.9 54.7 55.0 204.1 169.6 181.9 136.2 138.5 180.0 194.2 212.9 156.1 160.3 59.3 55.3 135.1 247.7 112.8 81.2 67.6 65.4 151.4 603.8 164.1 141.6 176.1 62.1 182.0 171.1 66.8 446.8 143.0 367.6 118.6 136.0 171.8 60.2 79.2 231.6 226.5 78.0 74.7 191.3 365.8 111.1 158.6 98.6 76.0 310.0 239.5 237.4 383.7 587.9 715.3 362.6 736.7 719.9 319.7 451.3 233.1 299.2 93.2 88.1 1039.3 334.0 235.2 356.9 465.8 528.2 150.4 236.0 323.0 305.1 535.7 566.7 233.0 251.4 528.8 369.1 466.0 515.9 500.4 448.1 140.9 310.1 120.0 511.9 309.5 120.4 106.1 237.9 290.4 161.2 111.7 511.9 175.5 255.1 380.1 208.4 223.5 332.3 334.5 278.4 304.2 262.6 201.8 585.4 402.1 255.1 551.5 325.3 136.2 130.8 166.5 488.1 161.1 371.8 26.0 39.3 17.4 15.6 41.0 20.3 19.6 17.7 18.8 41.3 12.7 15.5 15.1 22.0 19.2 58.1 26.4 18.1 27.5 54.9 62.4 54.7 55.0 59.3 55.3 67.6 65.4 62.1 60.2 78.0 76.0 53.9 76.9 102.7 38.5 60.6 70.2 117.4 80.4 150.2 41.0 125.3 98.8 220.5 71.4 124.9 75.4 43.8 133.9 34.7 176.2 135.0 106.7 111.0 152.8 178.3 80.8 96.5 72.6 44.5 122.1 166.5 156.3 203.4 168.2 68.4 199.3 86.7 199.3 94.6 69.0 45.9 291.1 30.5 70.3 66.4 398.0 148.8 75.1 56.9 46.9 77.8 53.5 20.6 46.3 58.1 116.5 118.4 174.9 354.7 203.9 136.3 117.9 163.3 40.0 65.7 126.5 117.0 132.1 120.7 192.4 77.6 215.5 50.7 134.0 163.2 156.1 HEATR3 FLJ20718 ENSG00000155393 "HEAT repeat containing 3" Q7Z4Q2 16 50065970-50107272 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041990, HPA058579" Uncertain Enhanced Nucleoplasm,Cytosol Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Cytosol "HPA041990: AB_10793940, HPA058579: AB_2683762" "unprognostic (7.36e-3)" "unprognostic (2.72e-1)" "unprognostic (2.01e-3)" "unprognostic (1.97e-1)" "unprognostic (1.20e-1)" "unprognostic (4.80e-3)" "prognostic unfavorable (4.11e-5)" "unprognostic (7.68e-2)" "unprognostic (5.11e-2)" "unprognostic (8.79e-2)" "unprognostic (4.96e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (5.16e-6)" "unprognostic (2.26e-1)" "unprognostic (1.76e-1)" "unprognostic (1.86e-1)" "unprognostic (3.17e-2)" 7.1 8.2 3.8 9.0 3.7 5.6 5.3 4.6 4.2 5.1 4.3 7.0 4.9 5.0 4.5 8.0 4.8 4.2 6.4 3.7 3.6 6.7 10.2 6.3 6.6 4.2 3.2 3.3 8.0 4.8 6.5 5.8 3.4 4.9 6.3 4.8 6.0 3.4 12.0 6.3 7.0 5.3 3.2 12.6 6.6 5.8 3.8 4.6 3.7 6.2 6.2 5.1 5.1 3.9 13.0 12.8 11.8 18.6 7.0 9.6 12.6 15.5 10.1 15.0 6.0 15.9 9.4 24.4 10.9 14.7 5.6 15.1 14.1 11.3 17.2 6.1 15.4 12.1 9.0 20.4 10.2 21.1 23.5 7.5 7.8 10.4 6.2 6.6 12.2 12.6 15.5 3.9 14.9 7.8 16.2 26.4 13.8 15.5 13.1 17.6 15.8 19.8 8.4 10.4 15.1 8.0 14.8 18.9 10.0 8.8 8.5 15.4 16.1 12.0 8.0 9.1 11.8 9.8 8.0 21.3 11.7 20.9 12.0 0.5 2.4 0.5 0.9 2.8 1.0 0.6 0.5 1.0 1.7 0.8 0.8 0.9 0.5 0.7 2.6 1.5 0.9 1.0 3.8 3.7 4.6 4.2 3.7 3.6 4.2 3.2 3.4 3.2 3.8 3.9 4.2 3.2 5.8 7.8 4.6 3.2 1.4 1.5 3.4 7.8 3.1 2.0 6.0 2.8 1.8 1.8 16.7 3.5 7.1 3.3 7.9 2.4 10.7 3.7 6.8 4.6 3.5 3.8 21.2 3.1 3.6 4.7 7.7 3.8 1.3 6.5 1.8 9.6 9.4 1.7 16.7 3.2 4.1 22.2 4.7 18.3 3.4 13.9 1.8 7.5 13.3 2.4 3.1 20.1 12.8 2.9 2.5 2.2 7.2 1.9 4.7 4.1 2.8 8.1 0.0 2.5 4.2 5.3 4.8 7.6 1.7 1.0 5.8 6.7 5.8 1.5 HEATR5A "C14orf125, DKFZP434I1735" ENSG00000129493 "HEAT repeat containing 5A" Q86XA9 14 31291788-31420550 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 67.8;Oligodendrocytes: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 120.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 120.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049539 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA049539: AB_2680809" "unprognostic (2.63e-1)" "unprognostic (2.24e-1)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (5.47e-3)" "unprognostic (3.97e-2)" "unprognostic (9.37e-2)" "unprognostic (8.02e-2)" "unprognostic (1.70e-1)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "prognostic favorable (1.11e-6)" "unprognostic (1.00e-1)" "unprognostic (5.93e-2)" "unprognostic (2.83e-2)" "unprognostic (6.00e-2)" 8.6 11.1 8.9 8.9 12.5 7.0 8.0 11.0 8.8 9.6 9.7 14.1 10.3 7.3 5.8 10.0 8.9 7.4 16.3 8.2 12.9 10.2 8.7 8.9 5.7 13.8 11.6 6.2 4.8 9.1 7.5 12.1 15.5 5.8 11.4 7.4 8.0 5.7 12.1 4.2 12.0 10.3 10.1 8.0 7.5 8.2 10.5 3.5 7.6 20.3 6.7 10.9 6.6 18.5 28.3 43.3 12.2 15.7 29.0 27.3 25.3 33.6 28.3 18.0 18.3 17.4 21.1 15.1 31.4 50.7 10.8 18.6 23.2 10.3 25.5 11.5 21.4 11.4 56.5 73.8 16.9 21.9 15.8 12.8 5.5 15.4 14.6 14.1 22.8 6.9 23.4 15.2 21.0 25.2 8.2 9.4 9.3 17.8 25.2 4.7 24.1 8.6 11.9 17.5 5.1 15.3 77.2 35.3 78.4 17.0 20.0 6.2 35.4 13.1 19.6 22.5 13.6 14.9 42.3 23.8 3.9 12.0 19.5 120.4 11.8 47.3 2.7 11.7 1.6 4.7 1.9 2.4 8.2 3.6 1.6 2.9 38.4 3.7 18.1 3.7 2.0 4.6 8.9 12.5 11.0 8.8 8.2 12.9 13.8 11.6 15.5 10.1 10.5 18.5 7.8 28.9 20.2 58.4 7.5 5.9 2.4 6.3 5.2 12.1 9.9 5.5 17.0 5.7 15.5 18.4 14.6 13.1 2.7 33.5 1.9 11.7 3.5 16.3 9.0 8.7 6.7 2.5 27.1 11.7 10.8 13.1 9.7 7.4 11.4 6.9 10.4 14.8 10.6 1.7 38.8 13.5 10.2 14.8 10.8 1.3 12.2 13.6 10.6 42.2 15.1 19.2 1.0 67.8 96.6 17.6 22.4 11.7 10.1 6.3 17.3 8.9 21.8 9.3 0.0 18.1 9.6 21.7 13.2 10.0 7.2 18.1 5.9 11.4 13.1 4.9 HECA "dJ225E12.1, HDC, HDCL, hHDC" ENSG00000112406 "Hdc homolog, cell cycle regulator" Q9UBI9 6 139135080-139180802 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 125.8;Langerhans cells: 153.3;Suprabasal keratinocytes: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012581, HPA042313" Uncertain Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA012581: , HPA042313: AB_10796903" "unprognostic (2.98e-2)" "unprognostic (2.39e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-1)" "unprognostic (7.31e-2)" "unprognostic (3.38e-3)" "unprognostic (4.29e-2)" "unprognostic (3.27e-1)" "unprognostic (7.39e-2)" "unprognostic (2.00e-2)" "unprognostic (5.77e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (8.09e-4)" "unprognostic (3.47e-1)" "unprognostic (2.59e-1)" "unprognostic (4.72e-3)" "unprognostic (5.77e-2)" 17.2 8.7 10.5 21.5 10.4 39.2 14.2 10.1 13.8 13.8 7.8 12.7 16.5 13.4 6.4 19.3 12.6 13.1 17.4 12.1 11.3 6.4 10.8 19.2 28.8 10.7 11.1 16.7 9.9 9.7 7.0 10.9 12.6 9.5 12.4 3.9 17.9 8.1 20.3 26.1 17.6 13.8 11.9 27.5 12.0 9.5 12.4 31.6 9.6 15.8 25.8 14.2 15.9 14.1 4.8 1.0 9.2 10.5 20.8 19.0 6.8 8.6 14.4 3.8 8.8 1.9 5.3 20.9 12.2 17.9 9.1 7.9 5.6 7.8 7.0 32.9 11.9 10.5 4.6 0.3 6.5 18.6 9.2 21.7 18.8 8.3 10.1 10.4 12.9 13.8 4.5 27.5 7.1 4.9 9.0 15.1 1.7 4.2 1.7 14.0 9.3 10.6 3.3 15.2 8.8 2.6 7.1 19.1 5.5 10.2 4.4 24.4 16.4 6.7 6.3 15.2 7.5 16.4 13.1 18.8 2.4 10.7 3.8 7.0 1.3 2.0 2.8 1.8 3.5 1.5 4.3 3.8 1.0 1.9 4.1 4.1 5.0 1.5 5.5 1.1 3.9 1.4 10.5 10.4 10.1 13.8 12.1 11.3 10.7 11.1 12.6 11.9 12.4 14.1 35.6 6.4 13.9 10.1 38.2 125.8 22.4 15.9 38.7 1.8 29.1 14.4 41.9 8.6 11.6 11.0 2.1 7.3 70.2 53.4 0.0 7.0 12.0 37.8 18.5 34.9 13.1 22.5 20.4 9.8 6.2 22.3 11.7 53.4 13.3 11.7 36.8 13.0 19.1 1.7 23.2 25.5 16.2 84.3 153.3 12.4 15.5 65.7 44.4 38.4 25.7 6.6 29.9 13.0 10.9 14.7 28.4 19.5 48.8 42.4 34.8 4.7 12.3 2.7 52.6 26.4 23.7 12.6 6.7 33.7 142.2 17.4 76.7 10.8 17.2 59.1 HECTD1 KIAA1131 ENSG00000092148 "HECT domain E3 ubiquitin protein ligase 1" Q9ULT8 14 31100112-31207804 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 218.4" "Cell type enhanced" "Detected in all" "Urothelial cells: 302.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002929, HPA054461" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nucleoli" "HPA002929: AB_1850574, HPA054461: AB_2682496" "unprognostic (6.71e-2)" "unprognostic (4.86e-2)" "unprognostic (5.31e-2)" "unprognostic (1.25e-1)" "unprognostic (1.64e-1)" "unprognostic (6.99e-2)" "unprognostic (1.32e-1)" "unprognostic (7.03e-2)" "unprognostic (2.29e-2)" "unprognostic (3.13e-2)" "unprognostic (3.60e-3)" "unprognostic (1.51e-1)" "prognostic favorable (1.20e-6)" "unprognostic (6.53e-2)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (9.91e-3)" 43.0 48.6 27.8 23.1 33.6 54.0 37.6 58.6 33.7 43.5 34.0 38.3 25.1 37.0 30.7 74.6 33.8 26.7 47.2 27.2 30.9 37.0 74.3 32.9 28.7 30.2 30.1 38.5 34.7 56.5 34.4 35.5 32.5 30.7 31.2 66.9 42.6 31.0 218.4 50.8 33.6 30.8 28.0 30.4 43.7 42.7 31.3 26.3 51.3 133.6 37.3 39.8 51.5 36.6 95.1 54.6 49.2 30.4 144.0 77.2 44.7 54.8 54.1 47.4 39.7 41.0 47.8 72.1 57.8 97.3 34.0 62.6 63.2 47.7 69.6 44.5 24.9 75.6 44.3 163.9 66.9 81.8 52.7 66.3 64.4 52.2 80.9 63.6 87.5 42.2 54.4 32.1 72.8 72.4 31.8 31.7 36.0 76.6 47.5 53.6 58.0 30.4 71.3 93.2 36.2 40.8 79.8 54.5 49.0 56.3 58.7 49.5 93.4 56.6 42.9 41.9 49.0 34.3 52.9 79.0 28.0 37.3 49.7 9.1 5.7 8.3 4.5 4.8 5.2 4.8 5.2 4.1 6.4 6.3 4.2 4.3 3.0 6.3 3.8 5.3 5.6 2.4 27.8 33.6 58.6 33.7 27.2 30.9 30.2 30.1 32.5 28.0 31.3 36.6 63.4 48.1 80.8 84.5 60.7 86.7 93.5 61.2 48.3 98.9 40.8 28.6 108.1 25.8 94.8 71.7 98.0 70.2 72.1 40.9 11.7 44.2 3.6 101.6 83.0 60.0 48.7 41.2 89.9 36.1 42.9 59.9 96.8 118.1 32.9 81.6 46.4 84.7 29.0 65.6 101.1 33.0 63.1 43.9 34.5 8.7 69.0 54.0 33.8 90.9 65.1 40.9 78.2 100.0 127.9 52.6 33.9 74.4 71.1 106.3 37.1 22.4 148.4 194.5 46.0 77.4 78.9 50.6 100.0 83.7 114.9 140.0 61.4 97.0 44.5 302.9 HEMK1 MTQ1 ENSG00000114735 "HemK methyltransferase family member 1" Q9Y5R4 3 50569152-50596168 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 149.9;Late spermatids: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034701, HPA034702" Uncertain NA NA "Cluster 44: Non-specific - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" "HPA034701: AB_10601429, HPA034702: AB_10673101" "unprognostic (1.27e-2)" "unprognostic (6.96e-2)" "unprognostic (2.49e-1)" "unprognostic (4.11e-2)" "unprognostic (2.43e-1)" "unprognostic (7.95e-3)" "unprognostic (9.39e-2)" "unprognostic (3.51e-3)" "unprognostic (1.45e-1)" "unprognostic (3.04e-1)" "unprognostic (5.33e-3)" "unprognostic (2.54e-3)" "unprognostic (1.58e-2)" "unprognostic (4.16e-2)" "unprognostic (4.53e-2)" "unprognostic (6.23e-2)" "unprognostic (2.44e-3)" 12.2 18.6 12.9 11.3 13.6 9.1 13.1 13.4 17.1 19.1 18.5 16.4 11.6 14.4 10.8 14.7 17.4 8.6 17.6 12.6 13.3 23.0 29.7 13.9 15.0 13.9 13.9 21.7 22.3 15.4 19.4 10.5 13.8 22.8 10.7 5.7 21.2 11.7 9.8 10.1 15.0 11.0 13.6 19.3 18.9 27.0 13.3 15.3 25.2 12.5 11.5 17.4 15.2 14.7 11.8 7.0 10.5 10.2 23.6 18.3 14.8 13.6 11.1 13.0 16.1 6.0 18.7 11.7 10.6 18.9 13.8 13.3 8.0 31.2 5.6 58.4 6.5 13.4 11.7 8.1 19.9 14.1 9.2 13.9 24.1 13.8 15.8 22.9 15.9 22.3 11.9 11.9 12.4 10.4 24.1 14.9 4.6 13.5 18.6 7.9 5.2 23.2 15.5 13.9 3.8 11.9 5.1 15.1 15.6 13.8 12.1 21.2 7.2 13.8 11.9 11.0 17.2 10.6 5.7 6.6 20.6 18.0 8.1 24.5 12.4 12.3 18.7 9.0 16.8 19.8 14.8 15.6 17.1 17.5 16.1 17.2 2.0 16.1 5.7 22.0 10.8 13.3 12.9 13.6 13.4 17.1 12.6 13.3 13.9 13.9 13.8 13.6 13.3 14.7 5.9 12.8 13.4 9.4 14.0 4.5 13.2 11.1 6.2 11.2 12.5 10.0 14.8 8.6 14.8 7.3 0.0 25.7 14.9 11.3 11.7 13.5 149.9 10.3 7.6 6.4 0.0 8.6 2.1 8.2 18.9 12.3 11.2 8.0 17.1 16.0 16.1 15.2 19.9 6.7 2.6 19.7 12.2 8.1 4.6 151.1 11.5 9.1 8.8 4.7 17.4 12.7 16.5 2.0 4.1 9.7 10.3 8.2 12.5 8.2 19.2 20.0 22.0 20.0 19.7 10.8 8.3 27.3 8.7 9.1 3.4 13.7 13.8 7.8 16.0 10.0 HEPH "CPL, KIAA0698" ENSG00000089472 Hephaestin Q9BQS7 X 66162549-66268867 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.9;smooth muscle: 82.7" "Cell type enhanced" "Detected in many" "Astrocytes: 78.0;Distal enterocytes: 211.0;Intestinal goblet cells: 95.6;Paneth cells: 96.9;Proximal enterocytes: 156.2;Undifferentiated cells: 72.4" "Cancer enhanced" "Detected in all" "colorectal cancer: 37.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 28.5;HEL: 25.4;HSkMC: 36.0;K-562: 72.5;LHCN-M2: 28.5;SuSa: 68.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005824 Approved NA NA 3700000 "Cluster 37: Intestine - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA005824: AB_1850603" "unprognostic (3.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.25e-2)" "unprognostic (4.25e-2)" "unprognostic (1.29e-3)" "unprognostic (2.25e-1)" "unprognostic (4.94e-2)" "unprognostic (6.17e-2)" "unprognostic (1.40e-2)" "unprognostic (3.35e-1)" "unprognostic (2.40e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (3.08e-2)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" 8.2 19.1 18.2 14.7 25.0 0.0 8.3 20.8 19.2 23.8 8.7 81.9 79.0 34.7 14.4 11.9 14.2 38.7 36.0 16.7 21.2 8.1 3.5 12.3 3.6 22.3 24.4 22.1 2.3 1.4 3.7 1.3 20.4 24.3 77.6 15.0 7.6 31.8 0.8 4.8 81.6 82.7 18.8 11.1 12.4 3.5 21.7 1.3 5.1 3.2 2.6 19.5 10.1 21.0 0.0 0.0 28.5 2.3 0.0 0.1 0.8 7.3 0.4 0.0 0.0 17.4 0.0 0.0 0.1 15.1 0.0 0.0 0.0 0.0 0.0 8.3 0.0 25.4 0.0 0.0 0.3 0.2 0.1 36.0 0.0 0.0 0.0 9.9 0.0 0.0 72.5 0.6 28.5 0.0 0.0 0.6 14.1 4.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 68.6 0.0 0.0 0.7 16.2 1.2 0.1 1.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 25.0 20.8 19.2 16.7 21.2 22.3 24.4 20.4 18.8 21.7 21.0 2.5 0.0 0.0 78.0 0.5 0.9 0.0 0.0 0.0 1.0 0.9 6.0 24.1 0.0 0.0 0.0 0.0 0.0 0.1 211.0 0.0 0.3 0.6 1.3 15.1 4.1 40.8 0.0 0.3 1.1 0.0 12.6 0.0 1.2 0.0 1.1 6.4 0.0 0.2 0.0 2.9 95.6 0.0 0.0 1.9 1.5 11.5 0.3 0.0 6.5 0.0 26.1 0.0 3.5 36.2 5.0 96.9 29.7 0.0 0.3 156.2 0.0 0.7 1.3 6.6 4.4 9.8 0.0 0.3 0.3 0.6 0.0 0.5 6.9 72.4 0.2 HEXA ENSG00000213614 "Hexosaminidase subunit alpha" P06865 15 72340924-72376420 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 234.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018082, HPA054583" Supported Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 20000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles Cytosol "HPA018082: , HPA054583: AB_2682531" "unprognostic (1.51e-2)" "unprognostic (1.73e-2)" "unprognostic (3.41e-1)" "prognostic favorable (5.63e-8)" "unprognostic (6.58e-2)" "unprognostic (1.32e-2)" "unprognostic (1.34e-2)" "unprognostic (2.82e-2)" "unprognostic (3.75e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (9.98e-2)" "unprognostic (3.98e-1)" "unprognostic (7.05e-3)" "unprognostic (3.02e-2)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" 49.8 56.1 18.3 37.6 21.1 110.0 58.5 20.4 21.6 73.8 28.5 55.1 49.8 42.6 164.6 24.8 47.8 76.7 54.3 19.9 20.1 90.1 79.4 84.2 54.2 23.0 21.3 39.3 30.6 54.0 26.3 102.0 24.6 45.3 67.0 32.1 45.0 53.3 22.1 21.8 41.2 59.5 21.7 54.7 45.1 35.6 27.0 38.1 76.5 33.2 42.4 71.6 19.7 29.9 39.8 66.4 27.8 53.8 223.6 253.1 39.7 54.8 274.1 115.3 182.8 34.6 282.7 32.9 50.9 110.0 59.9 77.1 74.5 34.6 72.5 26.5 30.0 41.4 60.4 60.9 172.9 99.9 113.1 216.7 101.3 50.4 89.3 210.3 107.4 48.4 65.1 197.6 156.0 33.9 21.7 50.0 16.0 128.9 0.3 22.3 60.6 75.3 129.1 61.6 23.8 26.4 136.5 126.6 307.3 56.1 23.4 123.9 54.1 171.9 70.7 160.1 59.3 104.7 151.8 33.4 62.1 130.4 85.3 24.2 84.6 60.1 43.8 35.7 38.7 41.1 28.8 38.9 98.0 38.0 22.5 33.2 8.1 51.3 13.3 37.3 28.2 63.0 18.3 21.1 20.4 21.6 19.9 20.1 23.0 21.3 24.6 21.7 27.0 29.9 68.9 64.1 62.4 19.9 46.3 22.2 33.3 94.3 19.4 42.4 28.6 30.4 26.9 30.0 68.0 66.2 106.3 150.2 54.2 36.6 60.7 88.3 20.6 27.2 30.2 50.8 47.2 19.1 22.7 38.0 68.0 78.7 42.8 40.6 29.9 49.9 43.5 42.9 234.3 26.9 24.7 46.3 81.4 92.8 75.0 13.7 74.3 118.1 94.3 24.4 60.3 38.4 82.4 20.6 26.7 39.1 74.6 44.8 37.7 33.0 68.5 66.7 37.5 56.9 46.0 24.5 31.7 24.3 32.3 13.5 15.6 157.6 36.7 45.2 50.6 27.5 HEXB ENSG00000049860 "Hexosaminidase subunit beta" P07686 5 74640023-74722647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 466.5;Hofbauer cells: 340.2;Syncytiotrophoblasts: 493.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 746.0;GAMG: 646.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055409, HPA056010" Enhanced "Intracellular and membrane" NA NA 40000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA055409: AB_2682808, HPA056010: AB_2683008" "unprognostic (3.45e-1)" "unprognostic (5.84e-2)" "unprognostic (1.85e-2)" "unprognostic (8.72e-2)" "unprognostic (1.12e-2)" "unprognostic (6.44e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (2.21e-1)" "unprognostic (5.01e-2)" "unprognostic (1.58e-3)" "unprognostic (6.45e-2)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (1.31e-2)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" 92.2 72.0 22.1 59.7 25.3 59.9 83.0 22.3 32.5 97.6 39.4 105.0 99.0 71.5 321.4 38.5 66.7 99.0 84.3 23.1 26.2 81.6 137.5 111.3 47.0 23.8 22.9 62.4 103.6 94.2 46.6 319.4 24.7 98.7 116.9 33.6 123.4 54.0 43.3 54.3 75.4 76.1 23.2 64.7 88.4 19.6 28.2 29.1 89.6 38.4 40.4 94.6 64.1 30.4 147.3 111.0 39.4 131.8 746.0 232.3 122.3 173.5 590.4 175.0 375.2 130.6 194.5 0.0 133.0 152.2 646.3 115.2 43.2 185.2 228.7 79.2 72.6 19.1 101.4 101.5 216.5 16.2 152.3 206.7 108.0 180.7 121.3 275.9 204.5 47.3 54.3 236.9 194.9 145.7 19.8 36.6 36.8 142.7 47.8 43.9 56.2 191.8 119.8 130.4 24.5 30.4 134.2 92.6 180.0 68.8 99.1 108.6 118.5 112.1 26.6 207.8 165.6 102.6 191.3 0.9 257.9 143.6 209.8 86.2 343.2 99.1 69.3 129.9 80.7 45.2 56.1 64.0 310.8 28.1 52.6 51.3 125.2 42.4 82.5 93.4 73.2 269.0 22.1 25.3 22.3 32.5 23.1 26.2 23.8 22.9 24.7 23.2 28.2 30.4 49.6 41.7 38.4 5.9 31.5 44.0 82.8 103.2 21.6 10.2 26.3 27.6 19.8 82.9 63.8 29.5 8.4 466.5 32.8 68.2 19.6 151.3 1.3 21.0 21.4 56.2 22.8 23.1 32.2 125.6 175.4 107.2 33.6 26.9 69.8 19.8 74.3 70.1 340.2 10.1 24.3 56.7 107.8 127.3 134.3 3.4 85.1 168.8 72.9 17.8 114.2 35.4 29.9 22.6 13.3 65.8 54.8 72.2 71.5 74.2 99.5 79.6 36.3 16.3 46.0 32.6 49.5 0.3 1.4 23.8 32.5 493.6 35.3 31.4 81.8 71.0 HEXD "FLJ23825, HEXDC" ENSG00000169660 "Hexosaminidase D" Q8WVB3 17 82418318-82442645 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 7.8;Cardiomyocytes: 6.1;Cytotrophoblasts: 5.9;dendritic cells: 10.1;Extravillous trophoblasts: 6.4;Hofbauer cells: 16.2;Plasma cells: 4.1;Syncytiotrophoblasts: 4.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 62.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022834, HPA023379, HPA027844" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli fibrillar center, Mitochondria" "HPA022834: AB_1850641, HPA023379: AB_1850643, HPA027844: AB_10600711" "unprognostic (8.69e-3)" "prognostic favorable (7.70e-4)" "unprognostic (7.92e-2)" "unprognostic (1.53e-1)" "unprognostic (3.51e-2)" "prognostic favorable (2.71e-4)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (2.71e-1)" "unprognostic (1.14e-2)" "prognostic favorable (5.57e-4)" "unprognostic (9.04e-3)" "unprognostic (1.83e-1)" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (1.24e-1)" "prognostic favorable (2.52e-5)" 31.5 20.5 6.9 4.4 7.4 9.0 21.0 10.1 7.8 32.5 9.3 17.0 4.1 22.4 3.9 15.4 25.3 3.1 15.0 6.6 6.3 27.0 29.8 14.8 7.0 7.6 7.0 29.9 55.2 4.1 31.9 1.8 8.0 34.6 2.1 3.6 19.8 4.2 28.4 14.4 24.2 2.1 6.2 36.1 21.3 12.5 7.8 5.0 25.4 7.6 3.4 17.6 21.1 9.6 3.4 8.0 3.5 5.9 11.3 9.9 10.7 4.5 5.4 4.4 4.7 3.1 11.1 9.5 4.8 1.7 3.0 4.9 2.0 2.5 1.7 6.4 15.5 4.1 8.4 3.9 9.9 2.9 10.2 7.3 1.9 1.3 4.6 4.7 5.7 5.9 5.5 3.2 1.3 7.5 10.0 8.6 3.7 6.5 5.1 11.5 3.2 17.9 3.5 4.5 4.9 11.1 9.4 5.5 9.1 1.3 8.4 10.7 5.2 2.8 5.3 2.2 3.1 14.6 2.1 7.0 2.3 6.9 3.2 9.5 3.0 5.6 18.4 24.3 12.4 8.3 3.9 6.5 3.8 11.0 5.8 9.3 5.5 25.4 10.8 62.3 3.2 11.2 6.9 7.4 10.1 7.8 6.6 6.3 7.6 7.0 8.0 6.2 7.8 9.6 7.8 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 5.9 10.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 6.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 4.0 1.4 0.0 0.0 0.0 HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699010-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 311.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 23.8;Fibroblasts: 95.8;Hepatic stellate cells: 25.0;Muller glia cells: 36.2;Smooth muscle cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 94.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.0" "Cell line enhanced" "Detected in some" "ASC TERT1: 171.6;HHSteC: 135.8;HL-60: 82.4;hTEC/SVTERT24-B: 87.4;Karpas-707: 240.7;U-87 MG: 62.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved "Secreted to blood" NA NA 4110000 14000 "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 2: Karpas-707 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "CAB010333: AB_647965, HPA040360: AB_2676939, HPA044088: AB_2678804" "unprognostic (5.24e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (7.45e-5)" "unprognostic (1.66e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-1)" "unprognostic (5.29e-2)" "prognostic unfavorable (5.59e-4)" "unprognostic (7.90e-3)" "unprognostic (2.92e-2)" "unprognostic (1.14e-2)" "unprognostic (2.06e-2)" 7.9 19.8 1.6 6.3 3.3 12.3 5.2 1.5 7.8 7.2 1.8 4.4 2.6 8.1 3.6 2.9 5.4 16.6 4.7 2.9 3.6 11.8 30.3 19.5 2.2 3.6 2.3 1.8 2.1 2.1 2.4 311.9 4.3 7.2 3.4 14.2 2.4 6.4 0.8 0.9 2.3 7.1 1.8 6.5 3.9 2.4 2.9 1.5 5.6 3.9 1.5 10.4 6.3 3.3 0.0 0.0 0.1 0.0 21.6 171.6 0.1 0.7 33.4 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.1 6.0 0.0 0.0 135.8 82.4 0.4 41.4 0.0 87.4 0.3 0.0 2.2 0.0 0.1 240.7 0.6 0.0 0.0 56.4 0.0 0.0 0.2 0.8 0.0 7.5 0.0 0.0 0.2 9.3 0.0 0.1 0.0 0.2 0.0 3.5 0.4 2.0 0.0 0.1 0.0 0.1 0.0 0.0 62.6 16.9 0.1 94.0 15.2 3.9 0.0 18.7 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 3.2 0.0 17.3 1.0 0.0 4.3 1.6 3.3 1.5 7.8 2.9 3.6 3.6 2.3 4.3 1.8 2.9 3.3 6.2 0.0 4.1 16.3 0.0 1.0 0.2 0.0 1.8 0.2 0.3 0.5 1.3 1.5 0.6 0.0 0.0 5.6 0.0 0.0 0.0 0.0 15.2 1.0 23.8 6.2 0.0 2.1 0.3 0.0 4.9 95.8 0.5 0.9 1.3 0.0 25.0 0.5 18.4 0.0 22.4 0.0 0.0 12.5 1.9 2.3 18.3 14.0 1.8 7.5 10.5 36.2 1.0 0.0 0.1 0.0 0.0 10.9 0.3 0.4 0.0 0.0 0.0 0.7 13.1 0.9 26.2 0.2 0.3 0.3 0.1 12.0 0.6 1.3 0.0 0.4 HGFAC "HGFA, HGFAP" ENSG00000109758 "HGF activator" Q04756 4 3441968-3449486 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "liver: 217.1" "Group enriched" "Detected in some" 5 "Early spermatids: 85.6;Hepatocytes: 72.0;Late spermatids: 165.9" "Cancer enriched" "Detected in some" 22 "liver cancer: 26.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "Hep G2: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA058279, HPA059076" Enhanced "Secreted to blood" NA NA 7590000 9300000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" "HPA058279: AB_2683665, HPA059076: AB_2683898" "unprognostic (2.70e-2)" "unprognostic (8.20e-2)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.39e-2)" "unprognostic (2.85e-3)" "unprognostic (5.37e-3)" "unprognostic (5.90e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-3)" "unprognostic (5.52e-2)" "prognostic unfavorable (9.31e-4)" "unprognostic (2.87e-1)" "unprognostic (2.24e-1)" "unprognostic (9.49e-2)" "unprognostic (3.74e-4)" 0.0 0.0 1.5 0.0 2.3 0.0 0.1 2.2 2.6 0.5 0.7 0.2 0.0 0.2 0.2 0.0 0.3 0.0 0.1 1.3 0.6 0.6 217.1 0.1 0.0 0.9 0.6 0.1 0.1 0.0 0.7 0.0 0.9 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.1 3.8 0.8 0.0 0.1 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.6 0.4 0.2 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.3 2.2 2.6 1.3 0.6 0.9 0.6 0.9 0.5 0.8 0.6 0.1 0.0 0.0 1.3 0.2 0.5 0.1 0.0 0.0 0.0 0.2 0.0 0.5 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 85.6 0.5 0.2 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.4 0.0 4.4 2.2 72.0 0.0 3.3 3.9 0.0 0.0 3.2 0.0 165.9 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.5 0.3 0.0 0.0 1.2 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.1 21.5 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 HGS "Hrs, Vps27, ZFYVE8" ENSG00000185359 "Hepatocyte growth factor-regulated tyrosine kinase substrate" O14964 17 81683326-81703138 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 137.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004872, HPA007728" Uncertain Enhanced Endosomes,Lysosomes,Cytosol NA NA 45000 "Cluster 18: Basophils - Vesicular transport" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Endosomes, Lysosomes" Cytosol "HPA004872: AB_1079053, HPA007728: AB_1850681" "unprognostic (6.52e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (4.29e-1)" "unprognostic (1.31e-2)" "unprognostic (4.91e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.61e-5)" "unprognostic (5.54e-3)" "unprognostic (1.09e-1)" "unprognostic (9.27e-2)" "unprognostic (5.30e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (4.31e-7)" "unprognostic (3.69e-1)" "unprognostic (2.27e-1)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" 73.3 95.6 101.5 24.8 102.2 54.5 69.7 98.9 127.1 81.4 98.2 75.7 29.3 66.7 32.7 118.8 70.2 27.0 82.1 103.3 99.3 100.8 85.7 80.1 30.6 105.9 103.2 74.4 85.1 28.1 81.7 24.8 104.3 86.3 25.3 15.7 72.4 29.6 93.7 95.2 81.2 28.5 98.1 100.6 84.6 105.9 102.7 35.3 68.5 18.5 24.8 81.1 83.9 104.1 104.2 93.1 47.8 66.6 56.0 59.8 57.3 65.5 86.6 99.6 76.8 72.6 65.0 23.4 47.2 106.4 88.6 63.2 43.7 100.6 45.8 19.7 76.0 58.8 98.8 117.5 92.8 47.1 55.4 78.1 100.9 93.9 121.9 82.7 120.9 44.5 54.8 30.4 92.1 77.9 58.1 71.4 43.8 75.9 88.9 51.3 48.6 41.0 94.5 87.7 54.9 86.1 54.6 114.9 78.3 48.3 82.3 98.6 87.3 119.5 82.4 69.6 123.3 41.6 17.6 21.8 96.9 53.3 89.4 48.8 28.7 38.9 24.5 32.3 16.6 16.4 18.5 19.4 23.5 15.8 14.1 16.0 44.7 27.1 33.6 19.3 22.3 35.9 101.5 102.2 98.9 127.1 103.3 99.3 105.9 103.2 104.3 98.1 102.7 104.1 20.8 25.6 28.7 17.6 22.0 27.9 23.8 27.7 29.6 30.6 27.0 25.9 3.1 17.2 27.6 22.0 35.5 34.0 27.4 60.9 1.9 43.3 72.3 45.6 28.7 26.3 11.4 23.4 14.2 42.6 36.5 21.8 68.8 66.1 23.4 26.3 16.1 20.7 29.5 23.5 12.6 32.4 22.4 22.9 26.6 137.8 28.9 30.3 23.2 15.9 28.1 20.6 25.7 6.6 16.1 68.2 42.7 23.0 27.6 53.9 41.1 14.6 32.3 35.5 13.1 17.8 24.0 36.9 32.5 37.0 30.3 50.2 23.5 22.1 36.2 50.8 HHIP "FLJ20992, HIP" ENSG00000164161 "Hedgehog interacting protein" Q96QV1 4 144646156-144745271 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3;lung: 16.2" "Group enriched" "Detected in many" 5 "Alveolar cells type 2: 175.6;Leydig cells: 136.1;Oligodendrocytes: 413.3;Theca cells: 162.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 322.6;TIME: 376.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012616 Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA012616: AB_1850687" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (7.12e-3)" "unprognostic (8.18e-2)" "unprognostic (2.43e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-1)" "unprognostic (1.95e-2)" "unprognostic (4.20e-1)" "unprognostic (1.90e-2)" "unprognostic (1.89e-1)" "unprognostic (9.66e-3)" "unprognostic (7.13e-3)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" "unprognostic (2.38e-1)" 2.3 2.3 10.4 0.4 25.4 0.8 0.3 10.7 19.6 1.3 0.0 3.2 2.6 1.6 3.8 0.0 0.1 1.1 0.2 17.1 11.0 0.8 6.8 16.2 0.0 20.0 20.2 0.6 2.6 0.0 0.3 0.0 13.6 4.7 3.2 0.9 0.3 2.6 0.4 0.2 3.7 0.1 9.4 0.0 5.9 1.5 18.1 2.7 0.6 1.3 0.0 5.0 0.3 37.3 0.0 0.1 4.9 0.1 0.3 1.9 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 3.0 0.2 0.3 0.0 2.2 0.0 2.0 0.1 0.0 0.1 0.1 0.0 0.0 10.4 7.8 17.2 322.6 29.1 0.1 0.0 4.8 0.0 47.7 0.0 4.4 0.0 2.8 0.4 65.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 376.7 0.4 3.9 0.3 2.5 2.2 0.0 10.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 10.4 25.4 10.7 19.6 17.1 11.0 20.0 20.2 13.6 9.4 18.1 37.3 0.3 12.8 175.6 3.9 0.4 0.0 0.0 0.5 0.0 42.7 0.0 0.0 1.2 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.5 6.0 0.6 0.0 0.0 17.6 0.4 0.0 38.9 0.0 0.4 16.5 0.1 9.3 0.1 0.1 0.0 13.9 0.0 2.0 0.0 0.4 4.5 136.1 1.3 1.8 1.0 0.0 0.3 0.0 8.5 413.3 0.1 0.0 44.0 0.0 0.0 0.0 0.0 4.4 3.3 0.0 1.7 0.9 0.3 0.5 0.0 0.6 0.0 1.0 162.7 0.0 0.0 HHIPL1 KIAA1822 ENSG00000182218 "HHIP like 1" Q96JK4 14 99645129-99680569 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.7" "Cell type enhanced" "Detected in some" "Astrocytes: 33.3;Bipolar cells: 10.5;Excitatory neurons: 8.3;Inhibitory neurons: 12.2;Muller glia cells: 13.1;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.1;fHDF/TERT166: 5.6;SiHa: 3.7;THP-1: 3.9" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA 120000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (6.16e-2)" "unprognostic (3.44e-2)" "unprognostic (3.43e-2)" "unprognostic (1.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (2.75e-2)" "unprognostic (4.70e-3)" "unprognostic (6.68e-2)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.35e-3)" "unprognostic (8.49e-6)" "unprognostic (2.52e-2)" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (7.12e-6)" 1.6 0.3 7.0 1.1 8.7 0.1 0.8 4.1 8.4 1.5 3.0 2.0 0.5 2.5 0.4 0.8 1.3 1.2 1.6 7.2 4.6 0.7 0.6 0.7 1.0 4.9 4.7 1.0 0.2 0.3 0.9 0.6 4.5 1.7 0.3 2.1 0.8 0.9 0.3 0.5 0.9 1.8 4.0 0.9 0.8 0.4 6.3 0.1 0.5 0.4 0.6 1.3 1.1 4.2 0.0 0.2 0.4 0.1 0.1 0.0 1.7 1.6 0.4 0.3 0.1 0.1 0.5 0.1 3.1 5.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.0 0.0 0.9 0.1 1.2 0.2 0.1 1.4 0.1 0.0 0.1 0.9 0.2 0.0 0.2 1.2 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.6 3.7 0.0 0.0 0.6 0.0 3.9 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 8.7 4.1 8.4 7.2 4.6 4.9 4.7 4.5 4.0 6.3 4.2 1.6 0.0 0.0 33.3 0.1 0.0 0.0 0.0 0.0 10.5 0.3 0.8 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 2.0 1.7 0.0 0.0 8.3 0.0 0.1 2.6 0.0 0.0 0.0 0.9 0.7 0.3 1.9 0.0 12.2 0.0 0.0 2.1 0.7 0.2 0.3 0.3 3.6 6.5 0.0 13.1 0.0 13.0 6.2 0.0 1.4 1.9 0.0 0.1 0.1 0.0 0.0 1.7 0.0 0.9 0.9 0.3 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.1 HHIPL2 "FLJ13840, KIAA1822L" ENSG00000143512 "HHIP like 2" Q6UWX4 1 222522258-222548104 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.8;thyroid gland: 2.0" "Group enriched" "Detected in some" 9 "Early spermatids: 16.7;Late spermatids: 25.5;Spermatocytes: 13.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 18.7;Hep G2: 5.7;RH-30: 21.3;SuSa: 7.8;U-87 MG: 10.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059673 Enhanced Uncertain Mitochondria,Cytosol "Secreted in other tissues" No NA "Cluster 1: Thyroid gland - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria Cytosol "HPA059673: AB_2684100" "unprognostic (1.35e-2)" "unprognostic (4.62e-3)" "unprognostic (2.91e-1)" "unprognostic (9.21e-2)" "unprognostic (3.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.74e-3)" "prognostic unfavorable (4.64e-4)" "unprognostic (8.07e-2)" "unprognostic (3.64e-1)" "unprognostic (2.29e-2)" "unprognostic (2.14e-2)" "unprognostic (0.00e+0)" "unprognostic (6.52e-2)" "unprognostic (4.21e-4)" "unprognostic (2.30e-3)" "unprognostic (8.38e-2)" 0.2 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.1 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 2.0 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.1 0.1 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 18.7 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.9 5.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.1 0.3 0.0 21.3 0.0 0.2 0.0 0.3 0.1 0.1 0.1 0.0 7.8 0.0 0.0 0.0 1.0 0.3 0.0 0.2 0.0 0.1 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 1.8 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 25.5 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.2 13.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 HHLA1 PLA2L ENSG00000132297 "HERV-H LTR-associating 1" C9JL84 8 132061486-132111159 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "Alveolar cells type 2: 19.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 5: NTERA-2 - Transcription" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (5.15e-2)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.5 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 HHLA2 "B7-H5, B7-H7, B7H7, B7y" ENSG00000114455 "HERV-H LTR-associating 2" Q9UM44 3 108296490-108378285 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 129.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 274.7;Paneth cells: 64.2;Proximal enterocytes: 186.8" "Group enriched" "Detected in many" 12 "colorectal cancer: 9.2;lung cancer: 5.0;pancreatic cancer: 5.1;renal cancer: 16.6;stomach cancer: 6.2" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 1.7;HDLM-2: 4.0;Karpas-707: 2.8" "Low region specificity" "Detected in all" HPA055478 Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055478: AB_2682830" "unprognostic (1.12e-2)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (3.11e-1)" "unprognostic (2.30e-1)" "unprognostic (1.59e-2)" "unprognostic (8.14e-5)" "unprognostic (1.76e-1)" "unprognostic (2.28e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-3)" "unprognostic (1.24e-1)" "unprognostic (1.62e-3)" "unprognostic (1.47e-1)" "unprognostic (2.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.66e-2)" 0.4 0.2 0.5 5.6 0.4 1.1 0.2 0.7 1.3 0.0 0.0 87.9 86.8 0.3 0.8 0.5 3.7 29.2 0.2 0.6 0.7 7.6 0.1 5.7 0.6 0.7 0.3 0.1 2.9 0.1 0.2 0.1 0.6 0.2 83.0 1.2 0.2 0.3 0.5 0.3 129.9 2.0 0.2 0.3 9.4 3.3 0.6 0.4 0.2 0.0 0.3 0.0 0.0 0.8 0.2 0.3 0.2 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.2 1.7 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.0 0.0 4.0 0.1 0.1 1.4 0.2 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 2.8 0.0 0.2 0.4 1.5 0.5 0.2 0.3 0.3 0.1 0.8 0.0 0.1 0.7 0.7 0.7 0.0 0.1 0.5 0.1 0.2 0.1 0.1 0.7 0.2 0.2 1.3 0.7 0.3 0.0 0.4 0.1 0.5 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.1 1.8 0.1 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.2 0.5 0.4 0.7 1.3 0.6 0.7 0.7 0.3 0.6 0.2 0.6 0.8 0.0 0.0 2.0 0.7 0.4 0.0 0.1 0.7 0.0 0.0 0.7 0.3 0.2 27.1 1.6 0.0 0.0 0.0 0.0 274.7 0.0 8.5 3.3 3.2 0.0 0.3 1.8 0.0 1.3 37.6 0.1 0.3 2.6 0.1 2.5 0.0 0.0 0.0 0.1 0.0 0.5 12.5 2.0 0.0 0.7 4.2 0.3 0.3 0.0 0.0 1.1 0.0 0.0 0.5 0.9 35.7 64.2 0.0 0.0 0.1 186.8 20.4 19.4 0.0 0.0 0.1 0.1 0.7 0.3 0.0 0.0 0.1 0.5 0.0 17.7 0.1 HIBADH NS5ATP1 ENSG00000106049 "3-hydroxyisobutyrate dehydrogenase" P31937 7 27525442-27662883 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 543.9;Proximal tubular cells: 355.1;Syncytiotrophoblasts: 272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019522, HPA021002" Enhanced NA NA 820000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA019522: AB_1850690, HPA021002: AB_1850692" "unprognostic (6.76e-2)" "unprognostic (1.09e-1)" "unprognostic (7.50e-2)" "unprognostic (9.79e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-3)" "unprognostic (7.22e-3)" "unprognostic (3.14e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-1)" "unprognostic (1.73e-1)" "unprognostic (2.05e-2)" "prognostic favorable (5.56e-11)" "unprognostic (2.49e-2)" "unprognostic (5.47e-2)" "unprognostic (3.38e-2)" "unprognostic (3.39e-2)" 62.1 79.0 15.0 11.9 18.0 7.6 56.5 18.8 18.4 37.2 27.6 33.8 35.0 35.3 11.6 20.4 41.6 28.4 66.7 13.2 18.2 160.5 197.9 20.4 15.1 16.1 17.0 33.4 34.2 97.4 14.1 47.4 16.9 44.7 34.5 31.5 45.4 42.4 117.4 13.1 32.0 37.2 15.6 18.0 34.0 26.4 17.4 21.2 54.5 203.2 14.8 33.5 18.0 17.5 74.0 46.8 31.0 50.1 89.1 109.8 29.3 44.8 83.8 46.3 52.8 27.6 85.2 29.9 38.4 81.4 79.4 67.1 34.5 66.5 67.3 20.9 34.6 14.6 73.0 114.3 73.8 22.4 16.1 101.2 54.1 34.8 120.6 112.1 61.7 35.3 59.7 29.2 117.2 31.2 21.4 34.7 30.0 110.4 56.0 21.2 31.2 33.1 106.5 43.6 28.6 31.7 93.8 173.5 77.9 76.4 75.0 48.6 40.3 28.6 49.5 47.1 31.2 51.8 39.7 17.8 41.2 67.8 85.1 5.3 17.3 8.2 16.7 22.8 22.5 18.2 18.4 19.3 19.3 16.4 24.0 19.8 3.0 22.9 22.0 9.1 13.2 17.4 15.0 18.0 18.8 18.4 13.2 18.2 16.1 17.0 16.9 15.6 17.4 17.5 17.3 9.6 6.4 56.2 14.1 21.3 43.6 51.9 17.1 15.8 58.8 28.2 105.8 58.6 37.7 47.8 4.2 181.1 8.1 23.3 543.9 35.8 58.5 22.8 28.5 21.5 15.6 33.2 64.4 29.1 138.9 44.6 43.3 27.3 2.5 12.0 25.4 149.8 53.7 23.5 85.9 28.9 40.7 28.3 10.0 62.3 44.7 18.5 65.8 51.5 11.0 34.1 8.2 147.2 131.6 28.0 24.1 36.9 20.1 46.1 58.4 355.1 50.8 11.9 46.0 31.6 35.4 35.0 44.3 22.4 15.5 272.4 15.2 77.3 38.8 47.3 HINT2 ENSG00000137133 "Histidine triad nucleotide binding protein 2" Q9BX68 9 35812960-35815354 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 633.9;Hepatocytes: 457.4;Proximal tubular cells: 578.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020961, HPA059109" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020961: AB_1850715, HPA059109: AB_2683906" "unprognostic (9.64e-3)" "unprognostic (1.53e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-2)" "unprognostic (5.51e-2)" "unprognostic (3.97e-2)" "unprognostic (1.07e-1)" "unprognostic (2.38e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.71e-3)" "unprognostic (2.87e-2)" "prognostic favorable (2.97e-9)" "unprognostic (4.29e-2)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (1.72e-1)" 50.8 79.5 41.7 15.5 43.9 27.0 48.5 44.9 46.8 23.2 40.3 42.6 34.9 25.9 48.6 27.5 29.9 14.9 87.4 39.8 43.1 91.1 169.2 30.2 21.0 43.8 42.5 19.2 65.9 72.6 41.2 17.6 42.0 33.9 34.2 20.4 39.7 26.1 80.1 33.4 34.2 20.1 43.9 33.8 56.9 29.8 47.3 38.8 38.4 85.5 23.8 30.6 24.2 44.0 30.3 76.1 47.1 45.6 29.0 24.3 33.2 27.8 39.2 42.3 46.1 49.9 31.1 39.9 31.7 25.3 59.8 29.3 21.2 40.9 44.1 87.8 40.7 42.2 64.1 45.8 68.1 25.1 40.0 27.3 36.8 40.2 64.8 16.7 33.2 91.4 25.5 117.4 34.0 60.3 61.3 31.3 21.4 70.0 138.7 60.8 33.1 53.6 61.5 21.5 38.4 46.4 36.0 42.7 49.6 27.5 45.9 44.6 16.5 22.0 37.7 30.4 35.7 107.0 127.3 57.4 49.8 32.2 36.2 41.0 77.5 4.7 68.9 58.5 62.4 98.9 73.7 69.8 113.4 96.7 56.4 58.6 7.6 66.8 56.9 246.1 107.3 81.2 41.7 43.9 44.9 46.8 39.8 43.1 43.8 42.5 42.0 43.9 47.3 44.0 49.3 22.4 17.5 5.2 57.9 45.4 63.4 137.6 49.5 39.8 99.1 105.8 115.1 130.1 68.3 80.9 20.9 154.9 69.3 148.2 633.9 115.5 67.3 83.9 28.6 47.8 96.0 100.8 1.7 172.1 71.7 53.2 52.5 44.6 18.4 43.5 63.1 457.4 113.9 20.2 2.5 127.4 126.1 61.1 51.4 128.0 40.4 47.7 120.9 1.9 74.1 123.7 87.6 1.5 4.5 85.6 157.5 44.8 77.7 40.7 181.4 578.1 105.1 45.5 46.0 54.2 72.6 38.4 77.4 64.7 45.9 56.8 51.0 85.1 126.7 84.8 HJV "haemojuvelin, hemojuvelin, HFE2, HFE2A, JH, RGMC" ENSG00000168509 "Hemojuvelin BMP co-receptor" Q6ZVN8 1 146017468-146036746 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "liver: 239.6;skeletal muscle: 591.1;tongue: 291.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 96 "liver cancer: 87.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 1.5;K-562: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA 69000 "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.30e-1)" "unprognostic (6.98e-4)" "unprognostic (7.06e-2)" "unprognostic (1.11e-2)" "unprognostic (2.77e-3)" "unprognostic (2.55e-1)" "unprognostic (8.50e-2)" "unprognostic (2.36e-1)" "unprognostic (7.14e-2)" "unprognostic (1.18e-1)" "unprognostic (8.96e-8)" "unprognostic (6.61e-2)" "unprognostic (2.72e-1)" "unprognostic (1.76e-2)" 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 7.9 0.1 0.1 67.5 0.0 0.1 0.2 239.6 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 2.2 0.0 0.0 5.9 0.0 591.1 0.4 0.1 0.2 0.4 0.2 0.1 1.6 0.1 0.3 0.1 291.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" P04439 6 29941260-29945884 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 3747.8;Proximal enterocytes: 5267.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 1363.9;fHDF/TERT166: 360.3;HBEC3-KT: 366.7;RPMI-8226: 372.1;U-266/70: 344.6" CAB078470 Supported "Golgi apparatus,Plasma membrane" NA NA 170000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Golgi apparatus" "CAB078470: AB_10985125" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (1.34e-2)" "prognostic favorable (9.59e-4)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.28e-2)" "unprognostic (3.42e-2)" "prognostic favorable (6.47e-4)" "unprognostic (2.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.54e-2)" 635.4 714.2 15.0 34.8 15.5 137.7 566.7 14.7 36.5 504.9 18.0 737.5 278.3 476.1 181.1 366.8 390.3 239.9 473.4 14.6 17.0 687.0 392.0 1007.3 132.0 19.1 15.8 338.8 200.0 18.5 406.5 52.1 16.5 370.9 94.6 9.9 364.1 1.2 246.5 673.3 959.1 14.5 16.8 1413.1 442.2 132.6 18.0 138.9 531.9 14.5 178.3 412.3 466.8 18.3 1363.9 35.0 0.0 0.0 205.9 193.7 1.4 1.4 2.5 2.1 2.3 0.2 0.1 4.0 0.6 360.3 179.1 31.2 0.2 366.7 0.5 3.1 13.5 237.5 9.5 7.4 11.2 0.5 14.4 2.0 0.0 2.5 1.1 0.6 0.2 177.8 0.4 1.4 0.5 0.0 1.1 24.3 2.9 0.2 4.1 27.5 2.5 372.1 246.7 276.5 0.6 12.4 29.3 0.2 11.8 82.8 1.6 30.4 5.8 18.7 0.8 5.8 4.0 344.6 92.6 77.7 0.4 199.9 0.2 321.6 119.0 182.7 164.7 95.5 134.8 96.9 125.4 146.3 18.6 64.3 86.5 119.2 248.7 133.1 109.6 54.6 222.2 191.9 15.0 15.5 14.7 36.5 14.6 17.0 19.1 15.8 16.5 16.8 18.0 18.3 1622.4 371.8 478.6 22.9 1316.2 856.4 886.2 1417.5 228.8 30.8 289.6 188.5 147.4 936.5 952.5 503.9 6.2 18.3 1879.4 2631.8 88.0 3747.8 52.2 239.4 374.0 1717.8 955.2 499.4 3.6 1310.0 18.5 743.5 853.7 556.2 603.0 253.3 1266.2 276.4 1840.9 37.0 19.3 1755.3 1265.4 1575.0 1124.0 95.6 704.6 1419.1 635.0 67.5 3258.0 170.4 3201.9 49.3 16.1 1802.9 2452.4 484.1 1110.7 1026.6 5267.3 294.9 609.6 24.4 558.8 397.3 579.2 197.4 23.8 216.5 947.7 31.7 2234.9 1021.3 1225.4 1262.8 HLA-C "D6S204, HLA-JY3, PSORS1" ENSG00000204525 "Major histocompatibility complex, class I, C" P10321 6 31268749-31272130 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1445.7" "Cell type enhanced" "Detected in all" "NK-cells: 3899.1;Proximal enterocytes: 3582.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 760.0;EFO-21: 795.5;RPTEC TERT1: 462.7;U-266/70: 481.6;U-266/84: 401.0;U-698: 289.3" "Intracellular and membrane" NA NA 240000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.17e-1)" "unprognostic (3.38e-1)" "unprognostic (3.05e-2)" "unprognostic (4.42e-2)" "unprognostic (1.56e-1)" "unprognostic (2.08e-1)" "unprognostic (1.51e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-3)" "unprognostic (3.23e-3)" "unprognostic (1.17e-1)" "unprognostic (2.39e-1)" "unprognostic (2.34e-1)" "unprognostic (2.00e-1)" "unprognostic (8.12e-2)" "unprognostic (1.87e-2)" "unprognostic (7.16e-2)" 538.6 417.5 0.7 274.6 2.4 122.3 507.4 0.8 0.9 464.4 1.5 594.3 1.6 434.8 259.5 277.6 411.7 103.9 424.3 0.3 1.1 561.0 485.7 1078.3 334.0 1.6 0.9 266.3 245.3 0.2 269.6 34.5 0.9 344.2 27.7 13.7 389.5 0.4 190.6 449.6 750.0 51.0 1.3 1445.7 419.4 62.3 1.2 2.4 382.9 0.3 0.7 372.7 377.5 0.8 760.0 1.1 0.0 0.0 120.1 94.1 1.7 3.1 0.9 1.1 2.3 0.9 0.0 0.4 795.5 190.8 208.7 0.5 0.0 188.1 0.0 1.4 170.4 0.8 8.1 0.1 0.8 0.5 0.5 80.5 0.2 0.5 0.0 272.4 0.0 92.5 0.4 0.0 0.0 0.0 7.8 4.8 0.5 0.0 0.8 1.9 0.3 1.9 462.7 0.0 0.9 1.5 0.2 0.1 2.2 0.3 0.3 3.3 0.6 196.4 65.8 2.3 2.5 481.6 401.0 289.3 0.3 8.2 0.2 1.9 2.8 2.3 0.7 0.8 0.6 0.4 0.4 0.6 0.4 0.4 0.4 0.5 2.8 0.8 0.3 0.1 0.9 46.1 0.7 2.4 0.8 0.9 0.3 1.1 1.6 0.9 0.9 1.3 1.2 0.8 1903.4 227.6 328.1 13.1 1576.5 729.1 757.8 1082.3 236.8 33.4 457.0 342.8 61.2 807.8 662.7 483.7 10.4 39.5 2429.1 1994.0 84.1 1966.4 25.6 233.7 343.8 1466.2 482.2 301.2 3.9 1511.3 1010.7 608.5 648.8 557.2 344.1 256.3 1390.0 469.2 1579.0 99.3 5.8 1375.7 923.7 2050.7 1492.7 32.1 507.3 1595.9 836.0 76.8 2570.1 207.3 3899.1 18.6 3.8 1272.7 2195.7 333.6 2482.6 1038.0 3582.3 232.5 548.5 24.0 1203.0 336.7 558.8 142.0 43.5 192.6 651.7 121.6 2212.1 786.8 1003.1 1160.6 HLA-DOA "HLA-D0-alpha, HLA-DNA, HLA-DZA" ENSG00000204252 "Major histocompatibility complex, class II, DO alpha" P06340 6 33004182-33009591 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 30.3;B-cells: 61.5;dendritic cells: 20.3;Kupffer cells: 29.4;Langerhans cells: 59.0;Macrophages: 37.7;monocytes: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "myeloid DC: 17.8;naive B-cell: 21.0" "Group enriched" "Detected in many" 11 "B-cells: 21.0;dendritic cells: 17.8;monocytes: 6.0" "Cell line enhanced" "Detected in some" "Daudi: 12.9;HDLM-2: 9.1;REH: 40.5;U-698: 8.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045038, HPA076922" Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" "HPA045038: AB_10959457, HPA076922: " "unprognostic (8.02e-2)" "unprognostic (2.30e-2)" "unprognostic (2.60e-2)" "unprognostic (1.19e-1)" "unprognostic (3.01e-1)" "unprognostic (3.83e-2)" "unprognostic (2.60e-1)" "unprognostic (9.86e-3)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (3.68e-1)" "unprognostic (4.39e-2)" "unprognostic (1.91e-1)" "unprognostic (9.95e-2)" "unprognostic (3.65e-2)" "unprognostic (8.70e-2)" "unprognostic (5.94e-2)" 7.1 6.1 0.2 7.8 0.4 1.5 6.5 0.4 0.4 4.9 0.3 3.2 5.0 3.0 1.2 2.3 5.0 2.1 2.2 0.3 1.0 8.0 2.8 12.7 15.1 1.8 0.8 2.8 2.4 0.9 3.5 0.0 1.5 5.0 4.2 0.4 3.2 2.1 0.8 2.8 15.2 1.1 0.8 28.7 4.0 0.4 0.7 7.0 4.5 1.0 19.8 3.0 3.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 12.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 40.5 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 1.4 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.1 8.2 0.0 0.2 0.0 0.0 1.0 0.0 0.0 6.0 0.0 14.6 0.1 0.3 17.8 21.0 0.3 1.3 0.7 0.2 4.7 5.0 1.0 2.4 0.2 0.4 0.4 0.4 0.3 1.0 1.8 0.8 1.5 0.8 0.7 1.2 7.5 3.2 30.3 0.0 61.5 1.9 0.6 0.1 0.6 0.0 0.5 2.4 1.6 1.5 2.0 3.7 0.0 0.1 20.3 0.3 0.0 6.6 0.1 0.3 0.2 8.5 0.0 2.5 0.0 0.2 0.1 1.2 0.5 0.3 5.1 3.5 1.1 0.0 13.4 0.0 0.0 0.1 2.0 29.4 59.0 0.2 0.3 37.7 0.0 6.5 41.9 0.6 4.1 0.0 0.1 0.3 0.0 0.0 0.9 0.6 0.0 2.9 1.4 0.2 0.0 0.7 0.6 0.0 0.2 0.5 1.1 0.1 4.1 1.0 0.3 1.2 HLA-DPA1 HLA-DP1A ENSG00000231389 "Major histocompatibility complex, class II, DP alpha 1" P20036 6 33064569-33080775 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 319.9;lymphoid tissue: 359.6" "Cell type enhanced" "Detected in many" "B-cells: 1387.3;Kupffer cells: 1794.6;Langerhans cells: 8122.8;Macrophages: 2736.9;monocytes: 2940.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 81.8;intermediate monocyte: 187.4;memory B-cell: 150.4;myeloid DC: 296.0;naive B-cell: 136.5;non-classical monocyte: 124.1;plasmacytoid DC: 82.6" "Group enriched" "Detected in all" 7 "B-cells: 150.4;dendritic cells: 296.0;monocytes: 187.4" "Cell line enhanced" "Detected in many" "Daudi: 37.2;HDLM-2: 115.9;REH: 30.3;U-698: 26.1" HPA017967 Enhanced Supported Vesicles NA NA 240000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA017967: AB_1853929" "unprognostic (8.93e-3)" "unprognostic (3.15e-2)" "unprognostic (3.64e-2)" "unprognostic (9.40e-3)" "unprognostic (9.07e-2)" "unprognostic (2.80e-2)" "unprognostic (5.69e-2)" "unprognostic (1.82e-2)" "unprognostic (7.28e-2)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (1.80e-1)" "unprognostic (8.38e-2)" "unprognostic (1.17e-1)" "unprognostic (4.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.06e-1)" 180.8 108.0 2.2 33.4 2.0 12.8 138.4 2.7 3.3 76.7 2.5 72.1 20.2 55.3 8.3 43.1 63.0 13.0 62.0 2.0 3.4 99.0 36.8 319.9 51.3 4.9 2.8 24.9 28.6 5.9 58.0 3.4 4.3 64.0 16.1 2.0 59.5 16.2 29.5 66.3 174.4 14.6 4.3 359.6 52.1 13.4 3.1 30.2 76.6 7.3 51.5 58.6 60.0 4.4 0.1 0.0 0.0 0.0 0.8 1.3 1.1 0.4 0.4 0.5 0.0 0.0 4.9 37.2 5.0 0.9 7.1 0.0 0.0 0.0 0.1 115.9 2.5 6.2 0.0 0.0 0.1 0.0 11.6 1.7 0.0 2.2 0.0 0.0 0.6 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.6 0.0 0.0 30.3 0.0 4.9 0.1 0.0 0.1 0.0 0.0 0.0 2.9 0.0 0.0 1.3 2.6 7.8 0.1 0.1 0.0 5.6 0.9 26.1 12.2 0.2 4.4 2.2 81.8 6.6 21.6 187.4 5.7 150.4 9.6 23.9 296.0 136.5 3.4 15.7 3.0 20.9 124.1 82.6 29.2 136.0 2.2 2.0 2.7 3.3 2.0 3.4 4.9 2.8 4.3 4.3 3.1 4.4 621.8 83.3 404.3 0.3 1387.3 206.7 7.2 12.4 9.1 2.8 41.2 110.4 12.1 64.3 107.3 23.9 0.0 4.2 574.9 10.6 9.8 36.4 2.8 1.2 4.1 337.8 10.2 80.3 0.5 18.8 9.3 53.7 48.4 2.8 64.6 14.3 62.2 7.5 1153.8 5.0 0.9 18.2 12.2 1794.6 8122.8 11.7 18.0 2736.9 302.4 32.8 2940.3 5.1 94.7 0.0 0.1 4.7 5.4 27.4 100.2 10.6 114.0 42.7 129.2 5.0 52.6 14.7 29.8 1.3 4.8 6.0 175.2 6.8 157.8 11.5 28.6 34.4 HLA-DQA1 "CELIAC1, HLA-DQA" ENSG00000196735 "Major histocompatibility complex, class II, DQ alpha 1" P01909 6 32628179-32647062 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 333.9;lymphoid tissue: 335.8" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 4114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 666.6" "Group enriched" "Detected in all" 19 "B-cells: 287.6;dendritic cells: 666.6;monocytes: 257.6" "Cell line enriched" "Detected in some" 7 "HDLM-2: 1419.1" HPA012315 Enhanced NA NA 200000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA012315: AB_1853930" "unprognostic (4.24e-3)" "unprognostic (1.47e-2)" "unprognostic (1.43e-2)" "unprognostic (7.94e-3)" "unprognostic (1.72e-1)" "unprognostic (6.07e-2)" "unprognostic (3.26e-1)" "unprognostic (5.81e-3)" "unprognostic (2.84e-2)" "unprognostic (1.17e-1)" "unprognostic (4.65e-2)" "unprognostic (1.15e-1)" "unprognostic (5.36e-2)" "unprognostic (6.74e-2)" "unprognostic (2.27e-1)" "unprognostic (7.43e-2)" "unprognostic (1.57e-1)" 61.7 45.7 2.3 111.0 2.2 7.1 41.6 2.4 2.8 49.9 5.2 76.8 0.1 27.7 32.2 32.1 29.1 127.4 20.8 1.6 5.1 39.6 95.1 333.9 335.8 4.3 2.6 18.6 15.0 2.6 15.2 13.7 2.7 15.1 115.8 1.9 34.8 7.8 7.5 30.0 74.0 19.2 5.4 180.0 103.3 12.2 3.4 234.3 26.0 0.0 322.3 175.9 16.3 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 213.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1419.1 0.9 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 4.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 2.4 0.4 0.0 0.1 0.6 0.6 63.2 1.5 156.1 24.4 0.0 0.0 1.9 105.8 0.5 2.4 257.6 1.0 287.6 3.3 16.5 666.6 274.1 0.4 4.3 3.0 8.2 68.3 162.7 21.6 129.0 2.3 2.2 2.4 2.8 1.6 5.1 4.3 2.6 2.7 5.4 3.4 11.1 67.9 12.8 86.3 0.0 972.8 50.2 0.4 4.3 4.6 0.1 9.8 28.6 2.1 7.2 19.4 0.0 2.1 0.8 179.8 0.9 1.9 4.6 0.6 0.5 0.4 97.4 0.0 38.3 0.1 4.6 2.4 14.7 10.7 0.9 50.4 0.8 12.8 0.6 381.0 0.0 0.1 0.4 2.0 518.6 4114.3 1.3 3.1 874.3 71.2 12.2 957.1 1.0 4.1 0.0 0.2 2.1 0.1 0.0 96.1 1.5 1.8 6.5 27.3 2.5 6.6 1.2 5.3 0.0 0.7 2.5 41.6 2.1 56.0 1.2 2.7 7.6 HLA-DQB1 "CELIAC1, HLA-DQB, IDDM1" ENSG00000179344 "Major histocompatibility complex, class II, DQ beta 1" 6 32659467-32668383 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 179.1;lymphoid tissue: 301.8" "Cell type enhanced" "Detected in many" "B-cells: 995.1;Langerhans cells: 4144.8;Macrophages: 1090.5;monocytes: 1038.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 153.5;intermediate monocyte: 142.9;memory B-cell: 159.2;myeloid DC: 386.3;naive B-cell: 169.1;plasmacytoid DC: 116.5" "Group enriched" "Detected in all" 6 "B-cells: 169.1;dendritic cells: 386.3;monocytes: 153.5" "Cell line enriched" "Detected in some" 6 "HDLM-2: 599.9" HPA013667 Enhanced Supported "Golgi apparatus,Rods & Rings" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Rods & Rings" "Golgi apparatus" "HPA013667: AB_1853932" "unprognostic (8.60e-3)" "unprognostic (1.91e-2)" "unprognostic (5.91e-2)" "unprognostic (9.85e-3)" "unprognostic (4.48e-1)" "unprognostic (5.30e-2)" "unprognostic (4.75e-2)" "unprognostic (1.06e-2)" "unprognostic (2.51e-2)" "unprognostic (1.48e-1)" "unprognostic (3.48e-2)" "unprognostic (3.94e-1)" "unprognostic (1.34e-2)" "unprognostic (3.13e-1)" "unprognostic (4.16e-1)" "unprognostic (2.43e-1)" "unprognostic (1.40e-1)" 56.6 23.9 2.2 77.8 2.2 40.0 45.3 2.7 3.1 19.9 3.0 45.8 0.2 18.9 126.9 21.3 22.2 43.6 21.6 2.0 3.6 34.3 37.1 179.1 301.8 4.7 3.8 7.4 14.3 10.6 21.3 10.1 2.9 17.1 39.0 1.7 24.2 11.9 9.6 31.8 78.0 11.2 4.6 139.3 128.0 7.0 3.1 108.2 26.3 0.0 122.3 89.9 16.9 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 93.9 2.2 0.0 0.0 19.2 0.0 19.2 0.0 599.9 13.4 0.0 0.0 0.0 0.0 0.2 7.8 0.0 3.0 0.0 0.0 0.0 0.0 2.9 0.0 1.8 0.0 7.2 0.1 0.9 0.1 0.0 0.0 0.0 0.1 0.2 0.0 1.3 0.0 0.1 1.6 1.1 1.4 0.0 3.3 10.9 0.2 0.0 0.6 0.8 0.4 68.7 2.1 66.0 47.1 0.1 0.0 0.3 153.5 27.9 12.8 142.9 6.6 159.2 6.9 20.0 386.3 169.1 0.4 6.3 11.8 10.4 41.1 116.5 41.1 217.0 2.2 2.2 2.7 3.1 2.0 3.6 4.7 3.8 2.9 4.6 3.1 5.5 162.9 41.7 181.1 0.0 995.1 89.9 8.7 23.1 31.3 5.1 16.8 32.1 3.2 27.1 40.7 18.4 10.4 1.4 188.2 10.3 7.9 38.8 16.5 4.1 1.0 135.3 22.8 37.2 0.2 20.0 3.0 18.8 41.8 5.2 38.5 7.9 25.0 2.3 422.1 0.0 0.8 24.7 12.2 487.3 4144.8 7.5 6.5 1090.5 97.8 8.4 1038.0 1.1 25.7 0.0 0.1 28.3 27.4 9.8 86.9 8.7 417.9 18.5 53.0 2.7 6.6 4.8 9.6 2.7 2.5 18.5 66.3 3.0 84.5 0.9 36.1 49.1 HLA-DQB2 HLA-DXB ENSG00000232629 "Major histocompatibility complex, class II, DQ beta 2" P05538 6 32756098-32763532 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 52.4" "Cell type enriched" "Detected in some" 33 "Langerhans cells: 1010.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.3" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073187 Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 31: Skin - Epidermis development" "Cluster 41: Macrophages - Immune response" "HPA073187: " "prognostic favorable (5.55e-4)" "unprognostic (3.75e-3)" "unprognostic (2.16e-1)" "unprognostic (2.50e-2)" "unprognostic (2.10e-1)" "unprognostic (6.60e-2)" "unprognostic (8.15e-2)" "unprognostic (3.73e-3)" "unprognostic (6.48e-2)" "unprognostic (1.25e-1)" "unprognostic (3.74e-1)" "unprognostic (1.94e-1)" "unprognostic (6.66e-2)" "unprognostic (1.23e-1)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (6.92e-2)" 4.6 1.9 0.0 0.0 0.0 0.1 3.8 0.0 0.0 3.3 0.2 1.8 0.3 0.9 0.1 7.3 1.4 0.5 1.4 0.0 0.0 2.3 0.6 14.6 0.7 0.1 0.0 0.4 0.6 0.0 1.9 0.0 0.0 1.5 1.0 0.0 2.5 0.0 0.8 52.4 6.5 0.0 0.0 12.8 1.3 0.6 0.0 0.2 2.4 0.0 0.4 1.4 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 1.3 0.0 0.0 1.1 0.8 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.1 3.2 13.0 0.0 5.9 28.4 0.0 0.1 0.0 0.0 0.4 1.7 0.4 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.2 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 2.5 0.1 0.0 0.0 2.4 0.0 0.1 0.0 0.0 6.2 1010.0 0.5 0.9 30.5 26.6 1.0 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.6 0.2 0.6 0.1 27.6 0.1 2.7 0.0 0.0 0.4 HMCN1 "ARMD1, FBLN6, FIBL-6, FIBL6" ENSG00000143341 "Hemicentin 1" Q96RW7 1 185734391-186190949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Cell division, Sensory transduction, Vision" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 20.3" "Cell type enhanced" "Detected in many" "Adipocytes: 33.8;Endothelial cells: 21.4;Fibroblasts: 22.2;Horizontal cells: 26.9;Microglial cells: 45.0" "Cancer enriched" "Detected in many" 6 "melanoma: 14.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 22.3;hTERT-RPE1: 20.1;MCF7: 76.5;SK-MEL-30: 50.2;WM-115: 43.9" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 9.9" "HPA008220, HPA051677" Uncertain Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" NA NA 9200000 "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" "HPA008220: , HPA051677: AB_2681572" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (8.00e-2)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "unprognostic (4.36e-2)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.59e-7)" "unprognostic (1.22e-2)" "unprognostic (5.17e-3)" "unprognostic (3.52e-1)" "unprognostic (2.00e-3)" 9.7 1.4 1.3 0.6 1.2 0.0 8.4 0.9 1.1 3.7 1.3 9.0 0.9 1.9 2.5 5.4 1.8 6.5 8.4 0.8 1.1 2.5 7.8 20.3 0.4 1.5 1.9 3.9 0.9 0.9 3.2 4.8 1.5 7.5 2.8 0.6 7.7 1.4 4.8 4.1 3.1 4.3 1.4 8.4 1.7 2.6 1.7 0.8 3.2 7.0 2.4 1.8 3.8 0.9 0.2 0.1 1.6 0.0 4.7 4.7 0.0 0.5 0.9 0.3 0.5 0.0 0.1 1.9 0.2 22.3 1.6 5.0 0.1 0.2 0.1 0.2 0.0 0.5 0.0 0.0 0.3 0.0 0.0 4.7 0.0 5.6 0.4 20.1 2.8 0.0 0.2 0.0 0.0 76.5 0.0 0.0 3.3 0.1 0.1 0.0 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.0 50.2 4.5 0.1 0.0 0.0 13.7 1.3 0.0 5.1 0.2 0.0 0.3 2.7 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.3 1.2 0.9 1.1 0.8 1.1 1.5 1.9 1.5 1.4 1.7 0.9 33.8 3.2 7.0 0.3 0.0 3.2 0.2 4.9 2.2 1.7 1.2 1.8 2.8 0.0 0.8 0.0 0.0 0.1 0.2 0.3 0.0 0.0 8.3 0.6 1.5 21.4 0.0 0.0 1.1 0.0 0.8 22.2 0.0 0.9 0.0 5.2 7.9 1.9 0.1 26.9 3.8 0.0 0.0 0.3 2.8 2.7 3.7 0.4 5.4 45.0 0.0 0.1 0.0 3.0 1.5 0.0 0.0 2.2 1.2 0.1 0.0 0.2 1.0 0.0 0.0 2.5 7.7 0.5 0.1 0.4 1.7 0.0 0.4 0.1 0.0 0.2 HMCN2 "DKFZp434P0216, FLJ23816" ENSG00000148357 "Hemicentin 2" Q8NDA2 9 130265882-130434123 "Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 33.9;intestine: 51.1" "Cell type enriched" "Detected in many" 8 "Skeletal myocytes: 283.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "pons: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 7.8;RH-30: 18.0;SCLC-21H: 2.6;SH-SY5Y: 4.1;U-138 MG: 2.9;U-87 MG: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053903, HPA070647" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 27000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053903: AB_2682301, HPA070647: AB_2686290" "unprognostic (1.61e-1)" "unprognostic (8.05e-3)" "unprognostic (1.69e-1)" "unprognostic (5.53e-4)" "unprognostic (1.05e-1)" "unprognostic (1.12e-2)" "unprognostic (1.10e-1)" "unprognostic (8.78e-3)" "unprognostic (3.23e-1)" "unprognostic (3.97e-4)" "unprognostic (3.36e-2)" "unprognostic (3.93e-1)" "unprognostic (1.04e-3)" "unprognostic (1.53e-2)" "unprognostic (3.62e-2)" "unprognostic (8.96e-3)" "unprognostic (8.63e-2)" 14.4 1.3 0.3 1.5 0.2 0.0 3.9 0.1 0.7 21.4 0.0 51.1 5.2 33.9 0.1 4.8 10.1 0.7 12.4 0.1 0.9 4.0 1.2 3.8 1.2 2.0 0.7 2.6 0.9 0.1 0.3 0.2 4.0 9.2 1.9 0.0 2.2 2.3 25.0 4.1 21.6 4.2 1.2 0.4 4.9 5.7 1.0 1.2 4.8 6.3 0.2 9.2 12.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.2 0.5 0.0 18.0 0.1 0.0 0.1 2.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.7 0.1 0.9 2.0 0.7 4.0 1.2 1.0 0.4 1.2 3.2 7.5 2.3 0.5 0.9 0.4 0.0 0.0 1.1 0.2 0.3 4.8 0.0 3.7 0.0 0.0 0.1 0.1 22.9 1.9 0.0 17.0 0.0 0.2 5.0 0.0 0.0 1.3 0.0 0.1 24.8 0.0 0.1 7.6 0.1 0.7 2.3 0.4 1.7 5.8 3.6 2.0 0.8 0.8 10.6 0.0 2.3 1.8 1.0 0.0 0.0 0.0 0.5 0.7 0.1 8.3 0.0 0.1 0.8 34.1 1.2 4.0 0.7 0.0 283.7 4.5 0.9 1.1 0.0 0.6 0.3 1.6 2.9 5.5 4.7 HMGCL HL ENSG00000117305 "3-hydroxy-3-methylglutaryl-CoA lyase" P35914 1 23801885-23838620 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 322.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.4;Proximal tubular cells: 216.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004727 Enhanced "Intracellular and membrane" NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA004727: AB_1079074" "unprognostic (8.24e-2)" "unprognostic (3.21e-2)" "prognostic favorable (7.67e-4)" "unprognostic (1.23e-3)" "unprognostic (5.47e-3)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (3.05e-1)" "unprognostic (8.24e-2)" "prognostic favorable (5.07e-8)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (8.60e-2)" "unprognostic (3.39e-3)" 27.5 63.0 26.3 16.8 27.5 7.5 25.8 27.5 28.3 27.5 33.0 53.3 45.7 20.2 47.2 32.8 35.6 26.3 42.5 24.6 26.9 115.5 322.5 23.6 21.7 28.0 26.2 21.6 33.4 60.2 26.3 19.9 27.7 31.7 52.9 16.1 30.3 27.9 63.7 25.5 40.0 23.3 27.4 26.8 40.9 17.9 30.1 23.4 40.5 70.2 25.1 28.6 24.2 29.6 28.5 16.0 17.7 13.4 70.6 53.5 6.8 22.0 38.3 23.3 28.2 10.2 53.7 14.8 44.3 34.6 19.0 22.4 21.3 35.7 25.2 30.4 16.1 19.8 13.8 23.5 90.9 7.8 12.7 62.4 52.0 30.8 58.5 62.5 32.2 27.4 20.6 20.3 43.3 29.3 12.2 15.3 4.6 77.4 22.1 17.2 14.5 27.9 55.4 14.5 14.8 13.2 28.6 10.8 49.3 23.3 33.9 19.3 24.3 19.3 11.6 35.5 9.7 28.7 15.2 13.3 47.7 28.7 23.0 103.5 67.0 66.0 36.3 66.0 39.8 45.9 39.1 42.1 58.0 51.2 39.6 37.7 25.5 54.4 77.5 43.9 45.5 61.7 26.3 27.5 27.5 28.3 24.6 26.9 28.0 26.2 27.7 27.4 30.1 29.6 19.9 12.8 25.7 14.0 16.3 5.9 29.9 54.3 9.6 24.6 19.9 17.1 33.7 41.5 30.6 49.7 18.8 43.0 10.0 48.1 119.3 57.7 2.3 25.0 17.5 22.5 9.0 18.7 4.3 24.0 27.3 20.8 30.5 23.1 17.7 29.7 30.4 172.4 61.6 35.3 5.3 49.5 28.5 23.5 7.7 3.6 21.8 23.5 21.4 8.4 41.4 37.1 24.7 6.0 12.5 31.2 53.8 24.5 8.3 29.4 70.9 216.8 31.5 25.5 6.6 17.1 21.6 6.6 5.4 13.8 6.5 41.3 15.2 65.6 48.9 24.3 HMSD "ACC-6, ACC6, C18orf53" ENSG00000221887 "Histocompatibility minor serpin domain containing" "A8MTL9, P0C7T4" 18 63949301-63981774 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.8" "Group enriched" "Detected in some" 4 "monocytes: 28.4;Oligodendrocytes: 11.1;Spermatogonia: 9.6" "Cancer enhanced" "Detected in single" "cervical cancer: 1.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 18 "dendritic cells: 1.8" "Cell line enhanced" "Detected in some" "ASC TERT1: 7.4;GAMG: 8.6;HDLM-2: 18.8;Karpas-707: 7.1" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "unprognostic (5.83e-3)" "unprognostic (1.40e-1)" "unprognostic (1.40e-2)" "unprognostic (5.42e-3)" "unprognostic (6.20e-2)" "unprognostic (1.16e-2)" "unprognostic (4.91e-2)" "unprognostic (3.80e-1)" "unprognostic (1.41e-2)" "unprognostic (5.19e-3)" "unprognostic (8.67e-2)" "unprognostic (1.44e-1)" "unprognostic (7.14e-6)" "unprognostic (1.22e-1)" "unprognostic (2.85e-1)" "unprognostic (1.45e-3)" "unprognostic (3.55e-1)" 1.3 0.4 2.3 0.8 3.3 0.0 0.3 3.8 6.1 0.2 1.3 0.4 0.1 0.0 0.0 0.9 0.7 0.0 0.9 2.2 2.7 0.5 0.7 1.8 1.6 5.7 3.8 0.2 0.2 0.0 0.1 0.0 5.1 0.2 0.4 0.1 0.2 0.0 0.1 0.7 0.9 0.0 3.6 1.1 0.3 0.6 3.5 0.9 0.7 0.1 1.2 0.1 0.5 6.8 3.3 0.0 0.0 0.0 3.2 7.4 0.0 0.6 2.1 0.3 3.9 0.0 0.8 0.0 0.0 0.9 8.6 3.4 1.3 0.2 2.5 18.8 0.0 0.0 0.1 0.0 0.8 0.0 0.0 4.1 0.0 2.7 0.1 1.0 0.0 0.0 0.0 7.1 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 3.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 2.3 3.3 3.8 6.1 2.2 2.7 5.7 3.8 5.1 3.6 3.5 6.8 0.1 3.2 0.0 0.3 0.0 1.7 0.2 3.6 0.0 0.1 0.1 0.1 0.3 0.0 0.9 0.0 0.0 0.4 2.9 0.0 0.0 0.5 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.5 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 2.0 0.0 2.7 0.4 0.3 0.5 0.0 0.0 28.4 0.9 0.0 0.5 11.1 0.4 0.1 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.4 1.5 9.6 0.9 0.1 0.1 0.2 0.1 0.6 0.1 HOGA1 "C10orf65, DHDPS2, DHDPSL, FLJ37472, NPL2" ENSG00000241935 "4-hydroxy-2-oxoglutarate aldolase 1" Q86XE5 10 97584323-97612802 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 51.8;liver: 54.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 35.8;Distal tubular cells: 29.4;Hepatocytes: 43.3;Late spermatids: 18.4;Proximal tubular cells: 98.0" "Group enriched" "Detected in many" 5 "liver cancer: 4.5;renal cancer: 9.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AN3-CA: 7.8;EFO-21: 9.7;Hep G2: 26.1;RPTEC TERT1: 31.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039466 Approved NA NA 16000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039466: AB_2676522" "unprognostic (6.44e-2)" "unprognostic (3.64e-2)" "unprognostic (7.50e-2)" "unprognostic (2.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.29e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-3)" "unprognostic (4.72e-1)" "unprognostic (2.37e-1)" "unprognostic (1.28e-1)" "unprognostic (6.80e-2)" "prognostic favorable (9.08e-4)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (2.94e-3)" "unprognostic (7.20e-4)" 4.1 8.3 5.8 0.2 7.4 0.4 1.9 9.3 5.0 0.7 11.4 0.2 0.3 1.1 3.7 1.0 2.0 2.5 21.1 4.4 6.5 51.8 54.8 1.4 0.3 8.2 9.2 0.2 15.3 5.7 3.6 0.1 8.3 1.1 0.1 0.8 1.7 2.1 3.4 1.5 0.3 0.5 7.3 0.4 0.2 0.9 7.9 0.3 1.8 12.1 0.2 0.4 0.9 10.3 0.3 3.7 0.1 7.8 1.5 0.3 0.1 0.1 0.2 0.0 0.0 3.0 0.2 0.3 9.7 0.2 0.5 2.6 0.0 0.2 0.1 0.1 4.0 0.1 1.4 26.1 1.1 0.2 0.1 0.3 0.7 0.1 0.1 1.9 0.4 0.1 0.0 0.4 0.6 1.6 0.1 0.1 0.2 0.2 0.0 0.1 0.6 0.4 31.5 0.6 0.6 1.0 0.1 1.3 0.5 0.2 2.8 0.0 0.2 0.8 0.2 0.3 0.2 0.5 0.9 0.1 2.0 0.1 0.1 0.6 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.1 0.4 0.2 0.2 1.0 0.2 0.2 0.3 0.2 0.1 5.8 7.4 9.3 5.0 4.4 6.5 8.2 9.2 8.3 7.3 7.9 10.3 0.0 0.0 0.0 7.2 1.5 0.1 0.7 0.5 1.8 0.4 0.1 0.4 6.0 35.8 0.2 9.2 0.0 0.1 0.0 0.1 29.4 5.9 3.8 1.8 0.1 0.0 0.0 0.0 1.3 0.2 0.0 0.2 0.0 0.5 0.0 0.1 0.4 43.3 0.1 1.7 1.2 0.0 0.0 1.3 0.0 18.4 0.0 0.8 1.8 1.0 0.0 2.0 0.0 1.5 12.3 0.5 0.1 0.0 0.0 0.1 0.0 98.0 3.2 0.3 0.0 4.5 0.9 0.0 0.1 0.7 0.0 0.0 0.5 0.0 0.0 0.2 HOXD13 "HOX4I, SPD" ENSG00000128714 "Homeobox D13" P35453 2 176092721-176095944 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "cervix: 14.2;intestine: 18.2;prostate: 9.7;seminal vesicle: 16.3;vagina: 17.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 12.4;Distal enterocytes: 5.5;Enteroendocrine cells: 29.0;Intestinal goblet cells: 9.1;Paneth cells: 5.5;Prostatic glandular cells: 6.3;Undifferentiated cells: 9.9;Urothelial cells: 6.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.4;HEK 293: 53.3;HL-60: 61.7;JURKAT: 16.7;NB-4: 36.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA064064 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA064064: AB_2685186" "unprognostic (2.04e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.95e-5)" "unprognostic (2.52e-3)" "unprognostic (7.25e-2)" "unprognostic (2.08e-2)" "unprognostic (4.62e-2)" "unprognostic (1.77e-1)" "unprognostic (4.66e-1)" "unprognostic (1.01e-2)" "unprognostic (2.82e-4)" "unprognostic (4.95e-2)" "unprognostic (3.70e-2)" "unprognostic (9.98e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.2 0.0 18.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 9.7 7.6 0.0 0.0 16.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.1 2.2 4.7 0.0 0.0 0.0 0.0 0.0 5.1 0.0 18.4 0.0 2.8 0.0 53.3 8.3 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 3.9 0.0 0.0 0.0 0.0 36.3 1.9 0.0 3.0 0.0 0.2 0.0 0.0 0.4 15.2 3.7 3.8 0.0 8.9 0.2 0.0 0.0 0.0 1.8 0.0 0.8 5.1 0.0 0.0 0.0 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.9 0.0 0.1 0.1 29.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.4 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 9.9 6.7 HP ENSG00000257017 Haptoglobin P00738 16 72054505-72061055 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Immunity" "Antibiotic, Antimicrobial, Antioxidant, Serine protease homolog" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 91 "liver: 61113.6" "Cell type enriched" "Detected in many" 43 "Hepatocytes: 59512.7" "Cancer enriched" "Detected in many" 81 "liver cancer: 1297.4" "Region enhanced" "Detected in all" "medulla oblongata: 29.7" "Group enriched" "Detected in many" 5 "classical monocyte: 49.3;eosinophil: 80.2" "Group enriched" "Detected in many" 7 "granulocytes: 80.2;monocytes: 49.3" "Group enriched" "Detected in some" 5 "Hep G2: 232.2;HSkMC: 121.4" "CAB003787, HPA047750, HPA066795" Enhanced Approved Vesicles "Secreted to blood" NA NA 998000000000 100000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB003787: , HPA047750: AB_2680146, HPA066795: " "unprognostic (6.38e-3)" "unprognostic (7.73e-3)" "unprognostic (1.23e-1)" "unprognostic (2.41e-2)" "unprognostic (2.34e-3)" "unprognostic (2.07e-1)" "unprognostic (7.79e-3)" "unprognostic (1.37e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "prognostic unfavorable (6.94e-13)" "unprognostic (4.34e-4)" "unprognostic (1.80e-1)" "unprognostic (6.61e-2)" "unprognostic (2.49e-2)" 673.1 11.4 1.3 26.9 1.7 231.5 34.2 1.4 2.9 71.9 3.6 3.6 1.5 3.5 2.9 5.3 74.6 1.3 146.7 1.4 1.4 19.8 61113.6 91.3 1.7 29.7 2.0 9.9 7.6 0.2 49.9 2.5 3.7 7.3 0.6 0.7 6.1 0.2 5.0 3.4 4.4 4.5 2.3 72.0 6.2 2.1 8.3 2.7 6.3 0.4 3.0 3.8 3.3 5.9 0.0 0.0 0.0 0.0 6.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 8.5 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 11.2 0.2 232.2 0.3 33.3 6.2 121.4 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 2.0 0.4 2.6 0.0 0.0 1.1 23.6 0.0 0.0 0.1 0.0 0.0 16.2 0.0 0.0 0.0 0.0 6.8 5.1 0.0 0.8 0.0 0.0 3.9 0.0 14.1 0.0 12.7 0.0 6.2 49.3 80.2 0.0 2.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 14.2 0.0 2.1 0.0 0.0 15.2 1.3 1.7 1.4 2.9 1.4 1.4 29.7 2.0 3.7 2.3 8.3 5.9 0.4 19.2 228.7 1.6 96.1 0.1 0.7 1.9 0.0 0.4 0.4 0.3 66.6 1085.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 56.7 0.0 1128.3 0.0 10.4 0.1 45.5 0.0 1.3 3.8 0.4 1038.7 59512.7 2.3 0.0 0.0 0.2 4.1 1381.4 0.0 0.5 10.2 7.8 1.8 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 1.5 7.5 0.2 0.0 2.6 1.8 0.0 0.0 0.1 0.3 0.1 90.3 0.0 0.3 0.1 HP1BP3 HP1-BP74 ENSG00000127483 "Heterochromatin protein 1 binding protein 3" Q5SSJ5 1 20740266-20787323 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028215, HPA054295" Supported Supported "Nuclear speckles" NA Yes 30000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA028215: AB_10601021, HPA054295: AB_2682440" "unprognostic (3.90e-3)" "unprognostic (6.83e-2)" "unprognostic (7.69e-2)" "unprognostic (3.66e-2)" "unprognostic (1.31e-1)" "unprognostic (1.25e-3)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.97e-1)" "unprognostic (3.26e-2)" "unprognostic (1.68e-1)" "unprognostic (1.94e-2)" "unprognostic (9.50e-2)" "unprognostic (6.86e-2)" "unprognostic (1.65e-1)" "unprognostic (6.30e-2)" "unprognostic (1.27e-1)" "unprognostic (2.43e-2)" 87.9 78.9 62.2 76.2 75.1 141.7 80.1 69.6 76.5 143.6 62.1 107.9 71.3 116.5 63.0 94.8 96.7 75.3 75.7 64.5 66.6 83.5 66.5 84.1 91.4 68.1 64.4 135.6 74.4 98.1 60.9 85.9 67.5 81.3 88.2 96.4 83.0 74.3 113.9 86.9 93.8 100.3 61.3 89.2 83.1 54.5 68.7 134.5 106.3 78.7 90.3 93.9 114.2 107.6 207.3 106.1 261.6 157.5 152.3 172.8 157.3 230.2 182.4 156.7 163.1 97.6 232.0 208.2 113.4 176.6 108.4 171.9 136.7 125.5 199.8 306.5 124.7 296.2 230.5 85.4 98.1 209.7 181.7 135.1 90.6 159.0 208.5 193.0 160.5 245.1 169.9 251.8 180.1 64.2 323.5 93.0 69.3 152.6 126.3 250.4 255.0 219.2 113.6 66.6 175.0 180.0 279.8 112.9 181.2 132.9 117.3 138.7 196.4 176.2 164.2 180.7 139.2 144.0 194.2 246.7 150.2 213.0 204.0 102.4 55.3 202.6 57.1 45.0 59.7 70.8 61.9 62.1 52.2 58.4 80.4 54.5 66.1 63.3 54.9 59.5 71.6 49.0 62.2 75.1 69.6 76.5 64.5 66.6 68.1 64.4 67.5 61.3 68.7 107.6 129.4 150.6 156.2 96.9 112.1 130.4 137.4 81.6 159.9 117.8 116.6 108.7 161.4 94.4 94.5 104.8 54.2 87.6 144.7 105.6 154.6 87.0 40.8 85.3 184.6 136.8 103.7 214.6 98.3 93.4 70.7 161.9 98.8 128.2 137.8 131.8 129.2 101.0 72.6 80.8 93.7 113.4 83.4 100.7 104.1 22.3 172.7 116.9 113.8 130.2 111.2 119.5 127.7 142.7 189.9 113.0 90.1 162.5 162.0 124.6 91.7 110.7 54.6 97.6 157.8 145.2 148.3 141.3 110.1 201.8 134.5 92.9 151.9 116.2 115.3 118.4 HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066573 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 200.5;liver: 866.2;pancreas: 272.1" "Group enriched" "Detected in many" 6 "Hepatocytes: 442.2;Proximal tubular cells: 201.0" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "EFO-21: 31.5;Hep G2: 47.8;T-47d: 22.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" 1.8 0.9 5.6 0.2 8.8 0.0 11.6 7.0 7.2 1.6 4.2 1.1 1.4 4.0 3.9 0.3 7.4 4.0 5.1 5.7 6.5 200.5 866.2 11.8 0.4 7.5 8.1 1.3 272.1 24.2 14.8 0.5 7.5 20.1 0.3 0.3 15.6 4.7 22.1 0.9 1.1 0.2 6.5 2.6 58.2 1.3 7.6 0.2 19.9 5.4 0.1 0.6 0.4 11.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.5 0.0 0.1 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.8 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.3 0.1 0.0 0.0 3.2 0.2 0.1 0.0 0.2 0.5 22.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.8 7.0 7.2 5.7 6.5 7.5 8.1 7.5 6.5 7.6 11.7 0.5 9.6 32.4 8.8 3.0 0.1 5.1 0.0 0.0 7.2 12.0 8.9 3.4 51.5 1.3 33.1 0.0 0.1 0.0 0.1 52.8 7.5 8.9 4.9 1.0 1.1 2.4 10.7 2.3 26.5 0.3 1.9 18.3 12.5 2.5 0.1 8.6 442.2 1.1 0.0 1.7 2.4 0.0 9.7 0.3 26.0 0.0 1.8 0.0 2.8 0.6 1.6 0.0 0.0 41.6 14.4 0.0 0.4 0.0 7.5 0.0 201.0 0.0 0.6 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.8 1.8 0.1 0.1 0.5 HPR ENSG00000261701 "Haptoglobin-related protein" P00739 16 72063148-72077246 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 811.9" "Group enriched" "Detected in some" 14 "Hepatocytes: 503.0;Smooth muscle cells: 128.8" "Cancer enriched" "Detected in some" 53 "liver cancer: 185.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 50.6" HPA047750 Supported Approved Vesicles "Secreted to blood" NA NA 49000000000 55000000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA047750: AB_2680146" "unprognostic (2.43e-1)" "unprognostic (4.69e-2)" "unprognostic (5.97e-3)" "unprognostic (2.42e-1)" "unprognostic (2.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.66e-1)" "unprognostic (8.21e-2)" "unprognostic (2.30e-1)" "unprognostic (3.44e-6)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" 5.5 0.5 14.1 0.2 15.3 0.1 2.0 13.9 16.7 1.2 11.3 1.2 0.6 0.3 0.4 0.3 1.3 0.7 137.2 13.7 14.3 4.0 811.9 1.5 0.7 14.4 14.3 2.0 0.6 0.0 0.3 0.0 13.6 1.6 0.1 0.8 0.3 0.3 1.7 0.6 1.1 0.1 12.8 0.3 1.7 1.9 15.2 0.2 1.1 0.2 0.1 0.4 1.9 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.6 2.2 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.2 0.0 0.1 0.0 0.6 0.6 0.0 14.1 15.3 13.9 16.7 13.7 14.3 14.4 14.3 13.6 12.8 15.2 13.1 0.0 0.0 7.5 2.3 0.4 0.1 0.0 0.9 0.0 0.1 0.0 0.0 22.4 12.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.8 0.0 5.3 0.2 0.2 0.0 2.6 0.0 0.0 0.0 1.1 10.8 503.0 0.0 0.0 0.2 0.0 2.0 12.8 0.0 2.8 9.9 0.0 0.0 0.0 0.0 4.9 0.0 0.0 1.2 0.0 0.0 5.3 0.0 0.0 0.0 13.0 0.2 0.1 0.0 6.1 128.8 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 16.4;Kupffer cells: 41.5;Macrophages: 20.2;monocytes: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.5" "Group enriched" "Detected in many" 4 "granulocytes: 18.5;monocytes: 27.2" "Cell line enhanced" "Detected in many" "Karpas-707: 39.8;OE19: 40.1;TIME: 25.8" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" No No 6500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" 3.4 4.5 0.8 6.6 0.9 2.3 1.0 0.6 1.7 2.4 0.4 5.9 2.1 2.7 0.2 9.9 3.9 2.7 0.8 0.9 0.9 1.6 2.4 3.2 4.5 1.8 1.0 4.5 0.8 5.6 1.2 2.1 1.3 0.6 6.4 0.2 9.7 0.6 0.3 5.3 2.8 1.9 1.8 6.0 2.0 5.7 2.7 2.0 0.7 0.3 3.9 3.0 3.3 3.6 13.5 0.6 0.1 1.7 3.2 0.9 0.1 1.5 8.2 3.6 16.5 0.0 11.0 0.4 2.3 4.2 20.8 12.3 16.8 2.5 6.5 1.4 1.7 4.2 9.0 0.2 1.4 2.5 8.4 1.8 5.1 2.4 15.4 1.4 18.1 2.4 0.1 39.8 1.5 2.8 0.2 0.3 0.7 40.1 2.6 0.0 0.4 0.6 10.2 0.3 9.3 0.0 17.7 9.8 1.4 2.6 1.5 3.8 25.8 1.5 4.6 1.4 1.7 0.5 6.2 0.2 9.9 11.4 2.7 0.4 27.2 0.0 1.4 10.1 1.0 0.2 2.7 1.0 3.0 0.3 1.7 1.6 18.5 2.3 1.5 0.1 5.2 7.9 0.8 0.9 0.6 1.7 0.9 0.9 1.8 1.0 1.3 1.8 2.7 3.6 0.3 6.4 4.4 0.0 0.7 3.4 3.0 3.3 2.8 0.0 0.3 0.5 0.6 0.0 5.6 1.8 0.0 0.5 2.4 10.1 0.0 1.9 0.6 2.3 3.7 1.0 6.6 2.7 0.8 1.3 2.9 1.4 4.1 13.2 0.0 0.4 2.9 0.6 16.4 0.0 3.8 2.8 0.0 41.5 3.0 0.3 0.6 20.2 0.0 7.5 33.9 0.0 3.1 0.0 0.1 1.1 6.7 0.0 0.7 1.7 4.1 0.0 2.8 0.0 0.0 0.1 1.2 0.2 1.0 4.0 3.7 1.5 6.2 1.4 4.6 3.7 HPSE2 "HPA2, HPR2, UFS" ENSG00000172987 "Heparanase 2 (inactive)" Q8WWQ2 10 98457077-99235862 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.6;cervix: 36.7;vagina: 27.6" "Cell type enriched" "Detected in some" 9 "Astrocytes: 900.7" "Cancer enhanced" "Detected in some" "prostate cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "BJ hTERT+: 10.2;HEL: 20.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044603 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA044603: AB_10794051" "unprognostic (2.44e-1)" "unprognostic (4.28e-3)" "unprognostic (4.83e-3)" "unprognostic (6.00e-2)" "unprognostic (1.15e-1)" "unprognostic (1.59e-1)" "unprognostic (3.05e-2)" "unprognostic (1.82e-2)" "unprognostic (4.03e-2)" "unprognostic (7.94e-2)" "unprognostic (1.38e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-4)" "unprognostic (5.79e-2)" "unprognostic (2.51e-1)" "unprognostic (9.39e-3)" "unprognostic (6.13e-3)" 2.0 0.0 9.9 2.0 20.9 0.0 5.2 15.4 7.6 36.7 3.6 2.9 2.7 4.5 0.0 14.3 1.8 1.4 0.1 5.8 21.1 3.5 0.0 2.2 0.0 23.2 29.6 0.2 0.0 0.0 0.3 1.5 21.5 11.1 3.0 0.0 2.4 4.2 0.3 3.2 5.2 1.7 16.5 0.0 4.6 2.7 28.5 0.1 0.1 3.0 0.4 18.3 27.6 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 10.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 20.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.9 20.9 15.4 7.6 5.8 21.1 23.2 29.6 21.5 16.5 28.5 11.9 0.3 0.0 0.0 900.7 0.0 0.0 4.8 0.0 0.0 0.0 0.2 0.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.3 0.4 24.8 0.3 0.0 0.0 6.4 0.0 0.0 4.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 97.3 0.2 0.0 0.0 0.0 48.6 0.3 0.0 0.0 40.3 0.0 0.0 0.0 16.6 4.6 0.0 0.0 0.4 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.9 1.9 11.5 2.1 0.0 0.1 0.0 0.2 0.8 0.0 0.7 HPX ENSG00000110169 Hemopexin P02790 11 6431049-6442617 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 908 "liver: 5440.6" "Cell type enriched" "Detected in some" 38 "Hepatocytes: 6095.8" "Cancer enriched" "Detected in many" 79 "liver cancer: 571.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "Hep G2: 21.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016725, HPA065318, HPA068847" Approved "Secreted to blood" NA NA 425000000000 190000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016725: , HPA065318: , HPA068847: " "unprognostic (3.39e-2)" "unprognostic (9.26e-2)" "unprognostic (3.88e-1)" "unprognostic (6.19e-4)" "unprognostic (2.05e-2)" "unprognostic (2.41e-1)" "prognostic favorable (2.26e-4)" "unprognostic (6.33e-2)" "unprognostic (5.67e-3)" "unprognostic (3.88e-1)" "unprognostic (5.08e-3)" "unprognostic (2.78e-2)" "unprognostic (5.82e-12)" "unprognostic (2.01e-1)" "unprognostic (4.48e-1)" "unprognostic (1.84e-2)" "unprognostic (2.14e-2)" 1.1 0.8 0.8 0.1 0.7 0.1 5.9 1.0 1.0 1.6 0.6 1.2 0.4 1.0 0.2 0.5 1.6 0.3 0.9 0.7 0.7 1.4 5440.6 1.2 0.3 0.7 0.7 1.6 5.5 0.1 1.2 0.3 0.7 2.4 0.6 1.7 1.1 0.6 0.3 1.6 1.1 0.3 0.6 3.8 0.9 1.1 0.8 0.1 0.9 0.0 0.1 1.1 1.2 0.7 0.2 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.1 0.3 1.3 0.0 0.8 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.6 0.2 21.3 0.0 3.0 0.0 0.8 0.6 0.1 0.0 0.5 0.1 0.2 0.4 0.1 0.1 0.4 0.0 0.0 0.3 0.9 0.0 0.1 1.3 0.2 0.0 0.1 0.2 0.0 1.0 3.0 0.2 0.2 1.1 0.0 0.5 0.3 0.2 1.0 0.1 0.4 0.2 0.9 0.2 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 1.0 1.0 0.7 0.7 0.7 0.7 0.7 0.6 0.8 0.7 0.5 3.2 0.5 0.3 15.1 0.6 0.2 0.2 0.0 1.5 19.1 7.7 0.7 80.1 0.2 0.0 2.1 0.1 0.1 0.6 0.0 0.1 2.3 0.2 0.3 6.2 0.0 157.7 0.7 0.6 0.1 0.4 0.0 1.2 0.0 1.1 132.8 6095.8 0.2 0.0 0.8 0.7 0.0 155.3 0.2 2.9 0.3 0.2 0.0 1.0 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.0 0.0 1.7 0.2 0.0 1.0 2.1 0.0 0.4 0.5 0.6 0.5 0.0 0.3 0.0 11.3 0.2 0.5 0.3 HRC MGC133236 ENSG00000130528 "Histidine rich calcium binding protein" P23327 19 49151198-49155396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 50 "heart muscle: 718.3;skeletal muscle: 453.0;tongue: 244.7" "Cell type enriched" "Detected in some" 17 "Cardiomyocytes: 1182.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 5.8;HSkMC: 5.6;K-562: 8.0;THP-1: 13.9;U-266/84: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA004833 Enhanced "Intracellular and membrane" NA NA 100000 "Cluster 38: Heart - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA004833: AB_1079083" "unprognostic (1.06e-1)" "unprognostic (1.04e-3)" "unprognostic (1.46e-2)" "unprognostic (4.94e-2)" "unprognostic (5.66e-2)" "unprognostic (9.75e-3)" "unprognostic (3.44e-1)" "unprognostic (1.74e-1)" "unprognostic (4.09e-1)" "unprognostic (1.62e-1)" "unprognostic (7.41e-3)" "unprognostic (5.85e-3)" "unprognostic (4.04e-2)" "unprognostic (6.68e-2)" "unprognostic (1.07e-1)" "unprognostic (1.86e-1)" "unprognostic (1.46e-1)" 9.3 3.6 2.5 0.6 2.7 0.0 5.7 3.1 4.0 6.4 2.0 2.4 0.9 6.3 5.4 4.5 9.2 2.2 718.3 2.5 2.3 3.5 1.9 2.8 0.8 2.4 2.6 4.6 1.3 1.5 1.5 2.1 2.6 4.3 0.9 0.8 8.1 2.5 453.0 2.9 2.3 2.1 2.2 0.5 1.8 1.4 2.8 0.6 4.7 244.7 0.4 3.1 3.9 2.4 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.6 5.8 0.0 0.0 1.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 13.9 0.2 0.0 0.0 0.3 0.0 0.0 4.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.7 3.1 4.0 2.5 2.3 2.4 2.6 2.6 2.2 2.8 2.4 3.7 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 1.0 0.8 1.0 1182.5 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.3 1.7 11.0 1.2 0.0 0.0 0.2 0.0 20.9 0.0 0.5 0.0 0.0 0.7 0.6 0.1 3.3 0.1 2.8 0.0 0.0 1.1 0.4 8.4 0.3 3.6 0.0 0.0 1.3 0.0 0.0 0.1 0.1 0.4 8.2 0.1 0.2 0.5 0.0 0.0 0.2 65.7 8.7 44.2 0.0 0.2 0.1 0.1 0.1 0.2 2.8 1.5 0.2 HRCT1 "LGLL338, PRO537, UNQ338" ENSG00000196196 "Histidine rich carboxyl terminus 1" Q6UXD1 9 35906202-35907136 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.4;breast: 24.9" "Cell type enhanced" "Detected in many" "Adipocytes: 72.4;Distal enterocytes: 232.3;Intestinal goblet cells: 57.8;Paneth cells: 316.5;Proximal enterocytes: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 18.0;HBEC3-KT: 10.3;HeLa: 15.9;Hep G2: 11.7;U-2197: 27.0;U-251 MG: 13.1" "Low region specificity" "Detected in some" HPA067038 Approved Nucleoplasm NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA067038: AB_2685767" "unprognostic (2.48e-2)" "unprognostic (4.88e-2)" "unprognostic (2.43e-2)" "unprognostic (2.49e-1)" "unprognostic (5.69e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.63e-2)" "unprognostic (2.53e-2)" "unprognostic (1.90e-1)" "unprognostic (2.44e-2)" "unprognostic (1.80e-1)" "unprognostic (1.18e-1)" "unprognostic (2.00e-1)" "unprognostic (9.41e-2)" "unprognostic (2.80e-1)" "unprognostic (9.43e-2)" 29.4 1.8 3.9 1.8 4.0 0.0 24.9 3.3 4.9 4.1 2.7 20.6 8.9 6.0 1.0 1.8 5.5 0.3 9.7 3.7 3.3 7.4 1.6 4.8 0.6 3.9 3.6 2.7 1.3 0.5 1.1 2.9 3.9 4.6 11.8 1.1 6.7 2.7 5.4 6.4 11.0 1.8 3.6 0.8 3.6 2.4 3.8 0.1 4.9 3.8 0.2 7.4 4.4 3.2 0.4 0.2 0.0 0.2 0.8 5.9 0.0 0.2 0.5 0.1 0.0 0.2 1.7 0.0 18.0 0.4 3.4 0.0 0.0 10.3 0.0 0.0 0.0 0.0 15.9 11.7 2.3 0.0 0.0 5.8 5.2 2.0 1.2 0.8 6.3 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.2 4.8 2.4 0.0 0.3 0.1 3.4 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.3 0.2 5.3 0.2 5.3 27.0 13.1 0.0 0.0 0.0 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 3.3 4.9 3.7 3.3 3.9 3.6 3.9 3.6 3.8 3.2 72.4 6.4 1.5 0.3 0.3 2.2 0.4 0.4 0.6 2.0 2.4 11.0 1.2 4.3 2.1 0.0 0.0 23.3 0.5 232.3 1.9 1.9 0.1 2.1 0.4 40.8 1.2 0.0 0.4 0.2 6.2 7.4 0.0 0.8 0.0 1.0 50.7 0.6 1.8 0.0 0.2 57.8 0.0 0.9 2.0 0.5 10.8 0.4 1.8 0.0 0.0 10.8 0.0 0.0 0.1 4.6 316.5 9.4 0.0 0.8 64.6 13.0 0.9 2.5 13.1 3.5 4.7 0.1 0.2 0.1 1.8 2.6 0.6 0.3 24.0 0.4 HRG "HPRG, HRGP" ENSG00000113905 "Histidine rich glycoprotein" P04196 3 186660216-186678234 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Blood coagulation, Chemotaxis, Fibrinolysis, Hemostasis" Heparin-binding "Disease variant, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 173 "liver: 5433.2" "Cell type enriched" "Detected in some" 29 "Hepatocytes: 479.7" "Cancer enriched" "Detected in some" 262 "liver cancer: 406.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 2.7;RH-30: 3.0;SiHa: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050269, HPA054598" Supported "Secreted to blood" NA NA 120000000000 28000000000 "Cluster 62: Liver - Hemostasis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 15: Hepatocytes - Hemostasis" "HPA050269: AB_2681068, HPA054598: AB_2682539" "unprognostic (2.67e-1)" "unprognostic (1.74e-2)" "unprognostic (7.58e-5)" "prognostic favorable (9.64e-5)" "unprognostic (1.44e-1)" "unprognostic (2.98e-3)" "unprognostic (2.22e-1)" "unprognostic (1.55e-2)" "unprognostic (1.14e-1)" "unprognostic (5.50e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 31.4 5433.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 3.0 0.0 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.7 0.0 3.7 0.0 0.0 0.0 0.0 5.9 0.0 0.1 0.0 0.0 0.6 0.0 10.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.7 479.7 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 HS2ST1 KIAA0448 ENSG00000153936 "Heparan sulfate 2-O-sulfotransferase 1" Q7LGA3 1 86914635-87109982 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 160.9;Excitatory neurons: 126.1;Inhibitory neurons: 130.1;Oligodendrocyte precursor cells: 95.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA043069, HPA043603, HPA075001" Supported Approved Mitochondria "Intracellular and membrane" No No "Cluster 38: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA043069: AB_10964127, HPA043603: AB_10963432, HPA075001: AB_2686726" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (1.28e-3)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (7.13e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (7.20e-2)" "unprognostic (5.34e-2)" "unprognostic (7.70e-2)" "unprognostic (1.70e-3)" "unprognostic (1.45e-1)" "unprognostic (5.80e-2)" "unprognostic (1.63e-2)" "unprognostic (5.07e-2)" "unprognostic (3.24e-1)" "unprognostic (7.58e-2)" 8.0 25.7 11.5 9.4 13.8 3.8 8.1 8.0 12.2 10.5 13.2 9.3 9.7 9.1 9.9 7.0 6.7 10.6 7.0 11.9 11.4 13.8 17.2 8.2 11.8 10.1 11.0 12.7 10.1 13.4 6.6 8.3 8.1 9.5 9.0 19.3 6.7 9.9 4.4 8.2 9.3 7.8 8.8 12.7 8.3 9.3 12.2 10.6 12.9 4.7 11.6 9.4 5.9 8.4 24.4 20.4 59.0 38.5 31.9 92.3 20.4 23.3 30.5 19.2 21.2 78.1 30.6 53.3 22.1 16.4 33.2 14.5 27.2 19.5 30.8 42.1 22.2 64.0 21.0 63.0 13.4 33.6 31.0 38.2 17.0 31.0 25.6 30.4 28.8 29.7 44.6 27.4 28.1 8.6 33.8 20.2 19.8 26.5 12.9 41.2 55.7 11.6 23.5 50.3 12.6 19.0 30.6 26.2 27.2 15.2 17.2 15.2 25.7 24.0 29.8 42.2 29.7 25.1 19.9 49.7 14.8 23.6 25.0 6.2 1.1 1.0 1.3 0.6 1.6 1.1 1.5 1.5 0.7 2.8 1.4 0.9 1.2 1.1 2.8 0.7 0.9 1.0 11.5 13.8 8.0 12.2 11.9 11.4 10.1 11.0 8.1 8.8 12.2 8.4 13.0 16.0 12.4 160.9 14.2 16.6 8.6 9.3 19.9 10.9 11.9 7.6 12.8 14.3 15.2 20.2 4.2 8.2 5.7 13.5 13.7 18.2 5.5 7.1 23.6 13.8 23.4 12.2 126.1 11.5 9.3 16.9 11.2 8.0 19.0 74.2 18.2 28.9 37.7 8.4 130.1 12.5 18.3 12.8 13.5 3.8 6.8 15.3 12.4 53.4 8.2 28.8 5.2 95.0 54.5 11.3 7.7 20.3 24.0 7.3 17.6 18.3 11.2 17.7 0.0 21.1 16.8 10.1 15.0 12.8 15.8 4.4 12.9 77.4 13.5 7.1 HS3ST1 3OST1 ENSG00000002587 "Heparan sulfate-glucosamine 3-sulfotransferase 1" O14792 4 11393150-11429564 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.4;ovary: 31.9" "Cell type enhanced" "Detected in many" "Club cells: 112.0;granulocytes: 96.3;Granulosa cells: 285.0;Peritubular cells: 90.3;Urothelial cells: 92.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 25.4" "Group enriched" "Detected in some" 36 "memory B-cell: 14.9;naive B-cell: 26.6;plasmacytoid DC: 42.3" "Group enriched" "Detected in many" 108 "B-cells: 26.6;dendritic cells: 42.3" "Cell line enhanced" "Detected in some" "A-431: 5.8;CAPAN-2: 20.6;HaCaT: 6.0;RPTEC TERT1: 13.2;RT4: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002237 Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA002237: AB_1079085" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (4.01e-2)" "prognostic favorable (7.73e-4)" "unprognostic (3.32e-2)" "unprognostic (8.90e-3)" "unprognostic (4.21e-1)" "unprognostic (2.08e-1)" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "prognostic favorable (5.99e-8)" "unprognostic (9.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "prognostic favorable (8.67e-4)" 2.6 2.5 2.3 2.7 1.9 2.0 1.9 25.4 6.9 2.4 0.0 2.1 3.7 3.4 1.3 11.6 4.4 12.7 1.9 1.6 4.7 5.9 0.4 1.8 2.3 4.7 3.3 31.9 1.0 0.1 4.7 0.7 3.8 2.0 1.1 1.0 5.6 1.5 0.4 0.5 2.9 0.9 4.4 3.3 6.5 1.3 5.8 1.3 1.6 0.2 1.2 14.5 2.6 6.1 5.8 1.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 20.6 0.0 0.4 0.0 0.0 6.0 0.0 2.8 0.0 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.1 1.6 2.2 1.2 0.0 0.0 13.2 14.5 4.6 0.0 0.0 0.1 0.4 0.2 0.0 0.0 2.0 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.2 14.9 0.0 0.0 0.7 26.6 0.0 0.0 0.0 0.0 0.0 42.3 0.0 1.1 2.3 1.9 25.4 6.9 1.6 4.7 4.7 3.3 3.8 4.4 5.8 6.1 3.5 3.2 5.8 0.0 13.1 9.1 13.5 70.1 5.2 3.7 2.4 9.3 3.2 32.9 112.0 20.2 4.2 0.5 21.6 5.2 0.0 25.0 1.7 3.6 1.0 28.9 2.4 0.0 13.4 2.1 42.1 13.2 23.9 14.9 96.3 285.0 25.0 0.4 37.6 1.7 35.0 7.2 71.2 3.5 3.7 2.0 8.7 12.5 1.8 6.5 4.9 32.9 8.2 24.1 0.7 51.9 6.5 90.3 0.0 5.6 2.7 19.1 61.2 2.6 0.0 0.5 17.5 5.4 5.6 36.6 8.1 1.4 1.4 68.5 4.3 92.9 HS3ST2 3OST2 ENSG00000122254 "Heparan sulfate-glucosamine 3-sulfotransferase 2" Q9Y278 16 22814162-22916338 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 29.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 99.8;Hofbauer cells: 16.9;Inhibitory neurons: 25.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 9.7;SH-SY5Y: 16.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017736 Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA017736: AB_1851095" "unprognostic (4.09e-2)" "unprognostic (2.90e-3)" "unprognostic (5.97e-3)" "unprognostic (3.46e-3)" "prognostic unfavorable (1.57e-4)" "unprognostic (2.00e-1)" "unprognostic (1.05e-1)" "unprognostic (2.17e-3)" "unprognostic (1.83e-1)" "unprognostic (2.75e-2)" "unprognostic (1.95e-1)" "unprognostic (2.45e-1)" "prognostic favorable (1.35e-4)" "unprognostic (4.89e-2)" "unprognostic (1.16e-1)" "unprognostic (1.35e-1)" "unprognostic (3.00e-2)" 3.0 1.2 11.5 0.0 16.8 0.0 2.1 0.8 29.9 1.8 0.5 0.7 0.0 0.7 0.0 0.2 0.6 0.0 1.0 11.7 6.2 0.4 0.6 5.4 0.0 3.9 6.6 0.3 0.2 0.0 0.3 0.1 5.2 1.9 0.2 0.4 3.1 0.0 0.4 2.0 0.5 0.1 2.4 0.3 0.7 0.3 2.6 0.0 1.8 0.1 0.0 1.1 1.1 16.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 16.8 0.8 29.9 11.7 6.2 3.9 6.6 5.2 2.4 2.6 16.3 0.8 0.0 0.0 1.6 0.0 3.6 0.2 0.0 0.0 10.3 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.6 0.1 0.0 0.0 2.3 0.0 0.0 99.8 0.0 0.2 1.9 0.0 0.2 0.0 0.0 0.4 0.2 16.9 0.0 25.7 0.0 0.0 1.0 2.7 1.5 1.2 7.3 0.0 0.0 0.0 0.0 0.0 3.5 1.8 0.9 0.0 5.7 0.0 1.1 0.0 0.0 0.0 0.7 0.0 0.3 5.8 0.1 0.0 0.0 2.0 0.3 0.1 0.0 0.0 0.8 HS3ST3A1 "30ST3A1, 3OST3A1" ENSG00000153976 "Heparan sulfate-glucosamine 3-sulfotransferase 3A1" Q9Y663 17 13494032-13601929 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 8.1" "Cell type enhanced" "Detected in some" "Astrocytes: 9.8;Granulosa cells: 11.6;Hepatic stellate cells: 7.1;Horizontal cells: 26.9;Leydig cells: 13.7;Squamous epithelial cells: 9.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "medulla oblongata: 5.9" "Immune cell enhanced" "Detected in some" "T-reg: 2.2" "Group enriched" "Detected in many" 5 "dendritic cells: 1.7;T-cells: 2.2" "Group enriched" "Detected in many" 4 "PC-3: 40.9;U-251 MG: 123.0;U-87 MG: 73.2" "Region enhanced" "Detected in many" "olfactory bulb: 5.0" "Region enhanced" "Detected in some" "olfactory bulb: 5.3" "HPA062518, HPA071530" Uncertain Approved Microtubules NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 40: Granulosa cells - Unknown function" Microtubules "HPA062518: AB_2684789, HPA071530: AB_2686411" "unprognostic (2.88e-3)" "unprognostic (4.21e-2)" "unprognostic (8.35e-2)" "unprognostic (3.50e-2)" "unprognostic (1.48e-3)" "unprognostic (4.44e-2)" "unprognostic (2.01e-1)" "unprognostic (4.46e-3)" "unprognostic (2.12e-4)" "unprognostic (1.12e-2)" "unprognostic (8.52e-2)" "unprognostic (1.55e-1)" "unprognostic (1.85e-9)" "unprognostic (1.83e-2)" "unprognostic (1.21e-1)" "unprognostic (1.33e-3)" "unprognostic (4.70e-3)" 0.4 2.0 0.1 1.9 1.0 1.0 0.4 0.0 0.6 4.5 3.2 1.2 1.4 0.7 0.1 4.6 1.3 0.3 2.5 0.2 0.0 1.4 1.9 1.2 2.6 5.9 1.4 8.1 0.3 0.0 0.7 2.7 1.1 3.1 0.3 1.3 2.0 4.9 0.1 0.7 1.2 0.2 3.5 6.4 0.6 2.3 0.1 0.3 0.3 0.0 1.6 0.5 3.4 0.5 0.1 0.3 3.3 0.0 2.7 6.8 5.1 18.2 4.4 3.2 2.0 0.0 0.6 0.0 2.6 11.2 0.0 0.0 0.1 0.0 3.1 1.1 18.3 4.9 1.5 2.0 1.6 0.0 1.2 4.9 0.1 8.5 2.2 5.5 0.0 0.2 19.2 0.0 3.8 2.5 0.1 3.3 3.5 0.0 40.9 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.1 2.0 0.1 0.6 0.2 3.1 0.4 0.1 123.0 0.0 0.0 0.0 73.2 0.0 9.1 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.4 0.5 0.0 0.0 0.5 0.5 0.2 0.3 0.0 1.7 2.2 0.3 0.1 1.0 0.0 0.6 0.2 0.0 5.9 1.4 1.1 3.5 0.1 0.5 0.2 0.0 0.0 9.8 0.0 0.6 0.0 0.0 5.7 0.3 0.0 0.3 0.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.4 0.3 1.1 0.0 0.0 1.8 0.2 0.0 4.7 0.0 0.2 0.0 11.6 7.1 0.0 1.6 26.9 4.1 0.0 0.0 0.8 0.3 0.1 13.7 0.0 0.0 1.9 0.0 2.4 0.0 0.5 0.2 0.7 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 4.0 0.3 0.4 9.3 0.6 0.1 0.1 0.0 0.0 0.0 HS3ST3B1 "30ST3B1, 3OST3B1" ENSG00000125430 "Heparan sulfate-glucosamine 3-sulfotransferase 3B1" Q9Y662 17 14301081-14349404 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 28.4;retina: 11.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6;dendritic cells: 32.5;Hepatic stellate cells: 25.7;Hepatocytes: 39.7;Syncytiotrophoblasts: 36.3" "Cancer enhanced" "Detected in many" "liver cancer: 5.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 35.1" "Group enriched" "Detected in many" 5 "dendritic cells: 35.1;T-cells: 26.2" "Cell line enhanced" "Detected in many" "AF22: 20.7;BEWO: 14.9;Hep G2: 18.8;HSkMC: 20.2;U-251 MG: 19.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA064126 Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA064126: AB_2685194" "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-2)" "unprognostic (5.55e-3)" "unprognostic (2.85e-3)" "unprognostic (5.22e-2)" "unprognostic (5.03e-3)" "unprognostic (1.79e-1)" "unprognostic (2.93e-1)" "unprognostic (8.13e-3)" "unprognostic (8.80e-2)" "unprognostic (1.13e-1)" "unprognostic (1.02e-3)" "unprognostic (7.77e-3)" "unprognostic (9.46e-2)" "unprognostic (1.91e-1)" "unprognostic (1.54e-3)" 0.9 0.9 0.2 4.6 1.0 1.4 0.9 0.3 1.3 2.4 1.5 1.2 1.3 0.6 0.2 1.8 0.9 1.4 1.5 0.4 0.4 3.0 28.4 1.6 6.3 5.4 2.5 3.5 0.6 0.3 0.7 3.5 2.0 2.0 1.7 11.5 5.3 2.0 1.0 1.5 1.8 0.5 2.9 3.4 1.2 0.4 1.4 3.2 0.7 0.9 4.8 2.6 1.9 0.9 0.0 0.4 20.7 0.0 6.2 6.9 14.9 6.1 8.7 5.3 5.6 0.0 0.1 0.0 0.0 8.2 0.0 0.1 0.5 3.3 2.7 1.8 4.5 0.5 2.9 18.8 8.1 0.8 3.2 20.2 1.1 1.9 4.8 1.2 0.0 1.1 6.6 0.1 4.3 1.1 1.0 0.8 0.7 0.1 0.6 3.9 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.8 0.4 0.6 0.0 5.2 0.0 0.1 19.9 0.0 0.0 0.0 4.0 0.0 1.2 0.2 0.4 0.0 10.2 0.7 8.1 0.9 12.0 8.0 0.8 0.7 12.1 11.8 0.9 6.6 0.8 35.1 26.2 5.1 0.2 1.0 0.3 1.3 0.4 0.4 5.4 2.5 2.0 2.9 1.4 0.9 2.9 0.0 1.1 6.2 3.5 11.5 0.3 4.9 21.1 3.2 1.2 2.2 3.0 10.0 3.9 7.3 39.6 7.2 32.5 0.0 0.0 0.7 14.3 0.3 1.5 2.9 0.0 0.4 3.3 0.2 11.9 6.6 0.0 0.8 0.0 2.4 25.7 39.7 1.6 8.4 2.2 0.1 2.0 3.8 12.9 3.3 2.8 6.7 1.8 1.9 1.3 7.3 14.4 3.5 0.1 0.2 0.0 1.2 2.2 1.1 0.4 0.1 3.9 17.9 13.1 15.0 2.6 4.0 0.3 10.0 14.8 36.3 12.4 0.1 0.2 0.3 HS3ST6 HS3ST5 ENSG00000162040 "Heparan sulfate-glucosamine 3-sulfotransferase 6" Q96QI5 16 1911475-1918415 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 75.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 10.7;Horizontal cells: 21.9;Suprabasal keratinocytes: 9.1;Urothelial cells: 24.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "A549: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.72e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-1)" "unprognostic (4.99e-3)" "unprognostic (2.10e-2)" "unprognostic (6.55e-3)" "unprognostic (2.42e-1)" "unprognostic (3.61e-1)" "unprognostic (2.26e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.5 0.0 0.0 0.0 14.4 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 1.4 0.0 0.0 1.9 0.0 0.3 75.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.1 4.1 10.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 3.4 0.9 0.0 0.0 0.1 0.0 0.3 0.0 0.7 1.8 0.0 0.2 0.0 6.3 0.0 0.0 4.5 10.7 0.5 0.1 0.0 0.0 0.1 0.0 0.4 2.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 21.9 0.1 0.9 4.1 0.0 1.5 1.4 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.0 0.0 2.7 0.2 0.2 5.0 0.2 0.0 0.0 0.3 0.0 0.0 4.5 9.1 0.1 0.1 0.0 1.7 24.9 HS6ST1 HS6ST ENSG00000136720 "Heparan sulfate 6-O-sulfotransferase 1" O60243 2 128236716-128318868 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 75.4;Granulosa cells: 285.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "EFO-21: 131.2;HMC-1: 206.6;SCLC-21H: 112.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044586 Approved Nucleoplasm "Intracellular and membrane" NA NA 72000 "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA044586: AB_10963057" "unprognostic (9.94e-2)" "unprognostic (8.93e-3)" "unprognostic (4.94e-3)" "unprognostic (6.69e-3)" "unprognostic (1.99e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-2)" "unprognostic (3.21e-2)" "unprognostic (2.87e-1)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (4.28e-2)" "unprognostic (1.21e-2)" "unprognostic (2.77e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-3)" "unprognostic (3.66e-2)" 16.2 63.4 36.2 8.8 33.8 5.1 16.1 24.4 45.5 15.5 10.9 15.4 8.7 12.3 6.1 34.1 17.5 21.0 19.0 35.4 26.5 71.4 46.8 17.0 8.4 32.1 34.7 26.4 30.8 8.8 15.2 12.0 33.6 28.2 6.9 26.4 26.0 22.8 36.2 26.5 15.1 6.4 31.2 32.1 12.7 25.0 39.9 14.5 14.2 18.7 7.4 19.4 23.1 28.9 12.5 17.4 46.0 26.5 17.5 32.5 24.7 15.1 19.1 14.8 8.1 9.0 8.0 11.9 131.2 19.4 6.9 32.5 17.5 29.1 5.5 19.9 18.1 10.5 6.4 87.9 21.1 18.4 206.6 43.9 33.9 11.9 3.6 4.9 8.0 31.8 6.7 12.1 5.4 25.7 49.6 81.0 55.3 4.7 10.7 16.1 12.6 61.9 13.4 36.3 112.9 28.4 12.1 30.1 6.7 30.6 12.2 6.9 9.6 13.1 28.9 49.1 12.3 7.2 7.6 2.7 7.9 13.0 9.7 3.0 0.7 0.6 1.0 0.4 0.1 0.7 0.4 0.6 0.5 0.7 0.4 0.4 0.2 0.2 1.5 2.3 0.2 0.6 36.2 33.8 24.4 45.5 35.4 26.5 32.1 34.7 33.6 31.2 39.9 28.9 9.5 25.6 8.9 20.9 4.9 16.2 11.2 16.1 14.8 9.4 15.1 12.8 7.3 10.0 10.3 75.4 31.3 9.7 7.3 22.3 5.9 15.4 0.9 22.9 11.5 12.6 3.0 6.9 24.2 5.8 36.9 12.6 4.1 39.7 57.0 285.6 30.0 23.8 10.7 21.9 20.3 6.5 8.2 14.2 9.2 3.3 11.8 9.1 7.2 5.6 6.7 8.2 1.0 6.6 10.4 6.6 12.0 17.0 3.2 9.7 6.9 3.3 8.7 32.8 6.6 7.6 9.4 1.1 3.1 18.3 17.0 23.3 3.5 27.1 3.7 8.9 HS6ST3 ENSG00000185352 "Heparan sulfate 6-O-sulfotransferase 3" Q8IZP7 13 96090107-96839562 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.5" "Group enriched" "Detected in some" 27 "Excitatory neurons: 1308.8;Inhibitory neurons: 893.1;Oligodendrocyte precursor cells: 968.6" "Cancer enhanced" "Detected in many" "breast cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RT4: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA078257 Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear membrane" "Plasma membrane, Actin filaments" "HPA078257: AB_2732374" "unprognostic (2.34e-2)" "unprognostic (1.90e-2)" "unprognostic (2.82e-2)" "unprognostic (1.72e-2)" "unprognostic (4.88e-2)" "unprognostic (2.78e-2)" "unprognostic (1.55e-1)" "unprognostic (3.67e-3)" "unprognostic (8.11e-3)" "unprognostic (1.19e-1)" "prognostic favorable (6.12e-5)" "unprognostic (1.54e-4)" "unprognostic (2.24e-1)" "unprognostic (1.57e-3)" "unprognostic (9.89e-2)" 1.4 4.2 1.4 0.2 3.5 0.0 0.3 0.0 9.0 1.8 0.0 0.2 0.4 2.1 2.1 0.4 0.5 0.2 0.9 12.5 7.3 0.8 0.0 0.0 0.0 0.1 5.2 0.1 2.2 2.1 1.9 0.0 0.3 0.2 0.1 2.2 0.0 0.2 1.1 0.5 0.4 1.5 0.3 0.0 0.9 0.3 6.1 0.0 2.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 1.1 0.0 1.2 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 17.3 0.9 0.7 0.1 0.1 0.0 0.2 0.5 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 3.5 0.0 9.0 12.5 7.3 0.1 5.2 0.3 0.3 6.1 0.0 0.0 0.0 0.0 33.6 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.3 0.6 0.1 0.0 0.0 1308.8 0.6 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 3.3 893.1 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 38.4 0.0 0.9 0.0 968.6 16.5 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.1 1.8 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 HSD11B1 "HSD11, HSD11B, SDR26C1" ENSG00000117594 "Hydroxysteroid 11-beta dehydrogenase 1" P28845 1 209686178-209734949 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 968.3" "Cell type enriched" "Detected in many" 9 "Hepatocytes: 646.2" "Cancer enriched" "Detected in all" 28 "liver cancer: 197.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 5.6" "Lineage enriched" "Detected in single" 17 "T-cells: 5.6" "Cell line enriched" "Detected in some" 5 "ASC diff: 989.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047729 Enhanced NA NA 110000 "Cluster 35: T-regs - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA047729: AB_2680135" "unprognostic (1.08e-3)" "unprognostic (2.13e-1)" "unprognostic (2.32e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "unprognostic (3.68e-1)" "unprognostic (2.02e-2)" "unprognostic (1.12e-1)" "unprognostic (1.30e-1)" "unprognostic (3.63e-2)" "unprognostic (8.35e-3)" "unprognostic (8.69e-2)" "prognostic unfavorable (1.97e-10)" "unprognostic (3.41e-2)" "unprognostic (3.91e-2)" "unprognostic (6.45e-2)" "unprognostic (1.59e-2)" 22.4 7.7 9.8 14.6 15.4 0.3 12.0 23.0 22.0 2.8 8.1 4.2 1.2 4.2 15.7 2.1 5.1 8.0 7.5 11.0 16.0 24.3 968.3 39.9 4.3 14.3 21.4 59.9 3.2 0.2 8.8 72.5 16.3 27.8 3.3 0.6 2.5 13.0 5.5 33.8 5.0 12.9 9.4 7.3 7.1 7.2 12.8 0.6 5.2 10.6 1.9 27.9 6.3 17.5 0.4 0.0 0.0 0.0 989.2 102.8 0.0 0.1 36.0 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.1 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 206.6 0.2 0.1 5.4 0.0 6.9 0.4 0.9 0.0 0.0 0.0 51.2 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.7 16.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 34.9 8.4 4.0 0.2 0.2 0.3 1.4 0.3 0.3 5.7 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 5.6 1.2 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 1.7 0.4 9.8 15.4 23.0 22.0 11.0 16.0 14.3 21.4 16.3 9.4 12.8 17.5 0.4 3.2 0.0 1.3 0.8 0.1 0.4 4.8 0.6 0.5 0.2 0.0 1.4 30.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.2 0.9 0.6 1.0 0.0 5.3 3.3 0.0 0.1 66.4 0.5 2.8 0.0 0.0 7.5 646.2 8.3 0.0 2.8 0.0 0.0 7.9 2.3 2.8 29.2 3.7 0.0 28.1 0.6 16.2 0.0 0.5 55.7 0.4 0.0 7.9 0.0 0.9 0.0 0.2 0.1 0.5 0.0 2.6 5.5 0.0 0.2 0.1 0.1 0.3 1.1 0.3 0.0 1.7 HSD11B1L "HSD1L, SCDR10, SDR26C2" ENSG00000167733 "Hydroxysteroid 11-beta dehydrogenase 1 like" Q7Z5J1 19 5680604-5688523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 58.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 19.0" "Low region specificity" "Detected in all" HPA049078 Supported Vesicles "Secreted in brain" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA049078: AB_2680622" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.73e-3)" "unprognostic (5.26e-2)" "unprognostic (9.37e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-3)" "unprognostic (1.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.75e-1)" "unprognostic (5.77e-2)" "unprognostic (4.52e-1)" "unprognostic (1.73e-2)" 3.9 9.8 46.6 1.3 46.7 2.6 5.1 32.0 58.2 5.5 34.0 8.4 1.6 5.4 5.1 3.7 6.7 3.0 5.9 46.1 41.8 12.4 5.4 4.4 1.4 38.4 36.5 6.7 7.0 7.3 21.2 1.5 37.2 6.1 1.0 6.3 5.8 4.1 10.9 9.3 3.4 1.6 32.9 3.2 6.3 8.1 42.4 1.6 8.6 3.3 1.0 6.0 4.3 39.1 3.6 3.0 11.3 2.1 5.0 5.7 2.2 2.7 4.4 1.1 4.8 1.3 3.3 0.8 5.9 2.2 0.9 1.7 1.4 1.8 1.0 3.2 3.6 2.3 3.0 2.2 3.6 0.9 7.9 5.5 3.9 1.6 1.6 10.4 1.8 5.1 2.4 2.9 4.6 0.3 2.1 2.1 3.0 14.2 4.1 3.6 0.5 3.1 9.5 0.8 3.2 19.0 0.5 1.6 12.8 3.8 2.6 0.7 3.2 2.7 5.0 4.9 2.2 7.6 2.8 0.9 7.7 1.2 2.4 1.5 1.0 0.5 0.6 2.7 0.6 0.5 1.4 1.6 1.0 1.1 1.8 1.7 1.9 0.7 1.8 2.2 0.4 0.9 46.6 46.7 32.0 58.2 46.1 41.8 38.4 36.5 37.2 32.9 42.4 39.1 8.2 0.0 2.6 13.7 2.6 8.2 8.6 12.9 9.6 11.3 23.7 23.1 2.3 10.0 8.6 23.9 14.6 4.7 3.0 4.5 15.6 12.4 9.5 21.8 6.0 6.1 25.7 1.3 24.7 4.7 6.5 8.1 4.6 5.4 10.2 12.4 8.9 4.1 5.1 8.4 20.4 4.6 12.2 2.8 6.0 13.9 7.2 2.4 5.4 1.9 3.1 30.5 1.0 14.1 4.6 4.8 4.3 12.8 0.9 8.4 4.1 33.3 31.2 12.9 0.0 8.1 9.5 10.8 12.7 4.8 10.2 2.9 3.1 16.6 3.7 9.7 HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452473-119637199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 320.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.1;Oligodendrocytes: 221.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 75.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 450000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favorable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" 74.4 85.0 37.2 41.9 50.2 19.7 44.4 51.1 50.0 68.8 47.2 64.5 79.3 34.1 53.0 50.9 39.1 52.5 68.6 34.9 50.7 84.4 320.0 75.6 33.2 50.6 49.5 34.8 55.2 75.5 26.5 53.4 49.2 56.8 65.9 27.2 44.9 79.0 59.8 51.8 87.6 39.5 44.7 36.6 53.8 20.9 49.9 31.9 133.9 52.8 39.7 57.7 31.5 56.3 68.8 59.8 104.1 143.7 261.8 120.3 57.9 63.4 80.3 57.3 103.0 49.4 112.8 84.4 128.0 70.6 81.0 68.7 77.0 144.4 84.3 94.6 79.8 118.1 62.0 96.9 65.8 38.0 169.9 110.0 56.3 64.9 54.7 69.3 103.9 59.4 41.0 48.9 64.2 64.0 59.2 23.6 82.1 161.1 43.1 68.7 103.0 104.8 92.2 192.7 81.1 70.6 149.0 23.4 78.7 93.3 88.7 68.2 67.6 52.7 38.1 66.5 53.1 26.3 55.3 32.6 63.7 104.4 56.7 75.5 27.3 49.9 6.5 15.5 7.3 11.1 5.8 5.3 21.3 10.3 5.5 5.2 4.9 6.9 17.1 13.8 4.1 12.2 37.2 50.2 51.1 50.0 34.9 50.7 50.6 49.5 49.2 44.7 49.9 56.3 38.9 73.7 125.2 47.3 28.2 14.9 42.5 43.2 24.5 19.7 31.1 22.1 76.4 64.3 52.3 36.8 14.6 64.3 19.1 40.0 84.1 39.9 8.8 29.0 48.9 32.3 33.0 42.1 92.9 35.8 29.3 35.6 48.4 35.8 68.4 25.3 32.2 225.1 77.9 15.2 102.8 45.8 22.4 51.8 13.8 13.4 34.5 46.7 8.8 49.6 85.7 47.3 9.2 78.4 221.5 20.5 29.6 51.1 23.1 24.8 85.7 65.4 33.8 18.6 6.6 29.2 32.2 30.6 22.7 34.7 17.2 65.0 15.7 57.2 55.3 39.7 HSD17B7 "PRAP, SDR37C1" ENSG00000132196 "Hydroxysteroid 17-beta dehydrogenase 7" P56937 1 162790702-162812817 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047496 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA047496: AB_2680068" "unprognostic (2.93e-1)" "unprognostic (1.36e-2)" "unprognostic (6.03e-2)" "unprognostic (1.12e-1)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (2.57e-1)" "unprognostic (2.51e-2)" "unprognostic (1.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.94e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.47e-5)" "unprognostic (6.25e-2)" "unprognostic (1.90e-1)" "unprognostic (6.35e-2)" "unprognostic (3.17e-2)" 4.3 16.1 3.3 5.1 3.1 2.8 8.2 3.0 6.0 5.6 3.8 6.4 6.7 4.0 7.2 8.9 5.1 4.2 3.5 2.9 4.0 5.2 30.2 7.6 8.3 3.8 3.7 6.8 5.3 5.1 7.7 4.6 3.9 5.9 8.0 4.0 6.2 3.5 6.0 7.6 6.6 4.4 3.3 5.6 5.9 2.6 3.7 8.1 6.1 2.8 8.1 5.5 5.6 3.7 12.6 12.2 32.4 13.8 18.4 18.3 20.2 4.6 15.9 9.4 19.0 17.0 35.7 29.6 10.6 4.4 58.3 19.1 30.6 43.4 9.9 12.4 15.5 7.7 8.2 26.8 15.2 13.9 12.7 11.6 23.5 36.8 11.6 7.4 15.7 19.4 14.5 19.0 8.3 8.9 17.7 13.7 20.5 24.4 15.3 9.5 19.3 18.5 33.3 19.5 27.6 14.6 8.0 7.7 7.9 27.5 12.3 17.1 9.8 4.4 10.2 6.7 10.0 11.2 12.7 29.4 6.6 1.2 11.1 21.7 6.7 12.1 13.6 6.8 14.8 12.6 10.1 13.7 6.9 11.9 12.9 12.4 5.5 8.2 8.5 10.0 17.9 12.2 3.3 3.1 3.0 6.0 2.9 4.0 3.8 3.7 3.9 3.3 3.7 3.7 8.8 0.0 25.5 22.5 22.6 11.0 19.5 48.3 35.9 23.6 24.9 11.9 2.4 12.8 26.1 11.0 62.6 17.2 19.9 14.9 3.9 16.9 2.0 9.4 7.9 12.0 6.0 4.2 8.4 27.1 15.1 13.1 8.6 9.3 5.1 32.8 8.9 62.0 13.4 11.8 9.1 14.5 18.3 5.0 16.9 1.9 6.8 12.2 17.8 5.6 10.6 14.3 16.5 12.5 22.6 15.0 17.9 7.2 18.1 19.0 12.1 10.2 19.9 44.1 0.0 5.9 10.5 4.9 6.6 15.6 12.6 19.2 23.5 34.1 11.6 12.6 HSP90B1 "GP96, GRP94, TRA1" ENSG00000166598 "Heat shock protein 90 beta family member 1" P14625 12 103930107-103953931 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Plasma cells: 4874.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003901, CAB005224, HPA008424, CAB078151" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 330000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 12: NES - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB005224: AB_2119181, CAB078151: AB_2665765, HPA003901: AB_1851181, HPA008424: AB_1851184" "unprognostic (1.03e-1)" "unprognostic (3.44e-2)" "unprognostic (1.18e-1)" "unprognostic (5.70e-2)" "unprognostic (1.17e-2)" "unprognostic (7.14e-3)" "unprognostic (3.00e-2)" "unprognostic (7.22e-2)" "unprognostic (8.77e-2)" "unprognostic (8.30e-2)" "unprognostic (2.76e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.03e-10)" "unprognostic (2.95e-1)" "unprognostic (2.39e-1)" "unprognostic (1.24e-1)" "unprognostic (1.28e-2)" 330.4 340.6 166.0 423.5 183.7 438.9 341.8 185.3 234.2 363.2 225.6 340.5 261.4 302.2 1032.5 157.5 305.5 218.9 309.5 164.4 206.2 317.1 736.4 271.1 245.9 205.0 191.3 302.6 397.1 336.0 247.2 521.1 201.6 360.2 387.5 185.6 254.9 382.8 87.5 120.0 269.5 385.7 188.8 322.4 297.6 180.7 196.5 228.2 1411.8 91.2 328.0 356.6 164.6 237.3 856.5 459.9 926.2 940.0 960.1 897.5 1229.9 1449.4 1133.4 776.0 1038.1 839.1 805.3 243.8 1102.2 1579.2 995.1 583.2 934.6 1578.9 1063.2 607.3 307.4 684.5 447.6 861.0 1457.4 702.1 514.6 519.6 690.9 920.0 1342.8 2643.7 1513.9 293.8 560.0 914.8 1039.9 314.7 409.2 768.3 756.9 925.5 544.5 372.2 597.1 1079.2 1064.3 527.1 271.5 645.7 889.2 912.0 932.7 1468.4 743.9 1016.2 854.4 566.1 476.0 462.8 607.9 945.5 949.0 455.6 1106.9 494.7 904.5 113.8 81.3 30.3 199.7 88.6 244.9 108.5 118.5 187.8 111.8 71.1 75.9 133.8 18.7 199.3 83.3 322.7 81.1 188.5 166.0 183.7 185.3 234.2 164.4 206.2 205.0 191.3 201.6 188.8 196.5 237.3 507.5 237.2 373.8 28.7 646.0 309.3 905.1 743.6 196.9 50.3 261.4 334.0 687.8 235.9 475.3 257.5 156.4 568.4 480.6 424.0 56.7 471.2 89.6 570.8 751.1 439.6 406.6 213.5 34.0 250.4 1081.0 714.0 390.9 690.9 405.3 500.6 446.9 891.9 553.1 77.4 41.9 631.5 238.0 300.1 309.8 47.0 563.2 378.4 421.6 52.5 240.5 141.0 199.8 30.2 61.3 321.8 419.1 337.7 4874.6 760.6 246.1 271.4 404.2 111.6 216.9 325.7 569.3 489.0 154.4 196.3 260.7 921.0 316.0 542.6 494.6 620.0 HSPA13 STCH ENSG00000155304 "Heat shock protein family A (Hsp70) member 13" P48723 21 14371115-14383484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 231.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014797 Approved "Intracellular and membrane" NA NA 3300000 "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA014797: AB_1857567" "unprognostic (2.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (5.77e-3)" "unprognostic (1.06e-1)" "unprognostic (1.72e-1)" "unprognostic (2.85e-3)" "unprognostic (1.41e-2)" "unprognostic (7.86e-2)" "unprognostic (1.64e-1)" "unprognostic (2.46e-1)" "unprognostic (5.62e-2)" "unprognostic (1.52e-2)" "unprognostic (1.65e-1)" "unprognostic (2.29e-1)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" 13.5 24.0 12.3 17.7 14.3 23.5 15.7 11.1 16.0 19.1 8.4 12.4 10.0 21.9 26.4 9.1 8.5 12.3 13.8 13.9 21.1 16.3 13.3 12.9 15.8 12.6 14.0 16.4 9.3 24.0 17.3 22.8 17.0 15.4 12.6 23.3 9.4 16.9 3.4 3.8 10.0 19.2 13.8 15.1 12.7 22.7 16.7 16.9 27.7 8.0 17.4 18.4 5.0 13.4 21.2 17.0 65.7 38.2 46.6 37.4 41.8 58.6 68.9 47.8 54.5 16.1 22.8 36.7 40.3 42.4 71.1 9.1 30.8 20.1 79.6 38.5 24.0 35.8 16.4 30.4 119.5 58.8 44.0 33.4 64.4 68.4 117.0 60.5 40.6 32.6 30.5 231.9 52.7 21.2 39.6 17.9 49.0 9.9 23.2 36.6 57.8 81.2 25.1 8.1 15.0 36.7 43.6 22.6 84.6 33.4 31.1 38.7 40.7 62.1 51.7 49.3 43.4 87.5 70.5 29.2 69.9 37.2 79.5 23.1 4.8 4.9 6.6 5.4 11.4 7.1 7.0 7.1 5.5 3.7 7.7 7.4 1.9 12.1 4.9 8.3 6.0 6.1 12.3 14.3 11.1 16.0 13.9 21.1 12.6 14.0 17.0 13.8 16.7 13.4 14.0 9.6 14.1 11.4 29.7 12.7 14.7 16.9 20.5 41.0 15.6 8.6 14.6 4.3 10.8 3.7 14.6 22.1 25.1 5.1 0.0 8.6 6.8 6.6 31.4 14.6 14.9 26.7 21.0 10.4 31.1 26.4 5.6 15.1 19.0 21.2 12.5 11.8 14.5 60.6 28.2 8.1 4.1 15.8 28.9 2.8 9.9 16.7 23.2 12.2 8.6 34.8 8.2 31.7 15.5 9.3 3.7 19.2 131.4 15.2 2.9 7.5 7.8 21.9 13.1 23.6 25.0 40.2 12.7 12.9 10.2 64.2 24.6 11.9 4.1 13.6 HSPA5 "BiP, GRP78" ENSG00000044574 "Heat shock protein family A (Hsp70) member 5" P11021 9 125234853-125241382 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1327.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005221, HPA038845, HPA038846" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 790000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB005221: AB_631616, HPA038845: AB_10673477, HPA038846: AB_10673478" "unprognostic (3.98e-2)" "unprognostic (2.50e-3)" "unprognostic (6.64e-2)" "unprognostic (9.60e-3)" "unprognostic (1.54e-3)" "unprognostic (6.02e-3)" "unprognostic (9.08e-3)" "unprognostic (9.11e-3)" "unprognostic (4.50e-2)" "unprognostic (7.45e-3)" "unprognostic (1.49e-1)" "unprognostic (8.96e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (7.28e-2)" "unprognostic (3.66e-2)" 211.2 170.2 83.7 276.1 91.7 856.2 147.2 101.8 107.3 202.9 112.0 181.6 166.5 183.6 379.1 150.7 177.9 130.6 284.0 90.2 126.8 168.7 327.8 182.8 145.4 105.8 107.0 142.1 260.7 223.3 182.7 311.3 120.2 192.8 183.7 105.1 211.0 167.5 87.6 143.2 175.8 205.2 111.4 129.8 177.9 173.5 101.7 116.2 692.8 85.2 180.0 197.7 105.1 163.9 593.4 380.3 480.2 631.3 505.6 592.0 1152.8 1047.6 728.2 675.9 778.5 558.4 1093.4 649.5 644.7 682.4 1564.0 732.5 403.3 839.4 684.7 403.7 213.8 396.7 392.9 945.1 2692.4 547.4 730.2 363.6 1515.2 551.3 2309.4 728.1 1065.6 129.0 291.9 870.3 482.2 382.6 249.7 297.8 559.1 1327.5 362.2 233.2 492.4 1061.2 608.4 352.7 248.5 448.0 648.1 653.4 1079.3 715.5 694.3 378.0 791.8 439.5 433.0 462.7 484.2 939.0 994.7 551.2 1070.4 435.9 689.0 455.5 366.3 305.3 384.7 361.8 390.0 209.0 276.7 360.1 322.0 173.9 224.6 277.2 280.9 362.9 252.5 349.5 213.6 758.2 83.7 91.7 101.8 107.3 90.2 126.8 105.8 107.0 120.2 111.4 101.7 163.9 227.1 185.9 273.5 38.5 254.0 292.9 1225.2 573.2 192.9 97.3 193.7 166.2 803.4 97.2 416.9 112.2 352.3 505.9 408.7 426.5 45.0 415.0 86.2 372.1 402.2 247.9 508.8 82.3 19.7 258.4 955.2 455.5 258.4 467.4 334.2 304.6 147.4 379.4 449.4 63.9 34.6 508.2 195.3 133.4 271.0 50.3 175.2 261.6 181.5 30.0 135.0 134.6 80.3 29.7 41.1 313.7 408.3 174.5 1041.5 360.8 196.9 121.2 267.6 176.6 118.3 245.9 673.8 435.7 204.3 167.4 236.4 1327.5 323.8 243.0 376.4 795.4 HSPBP1 FES1 ENSG00000133265 "HSPA (Hsp70) binding protein 1" Q9NZL4 19 55262223-55280381 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 270.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005865, HPA070398, HPA071444" Supported Approved Vesicles,Centrosome,Cytosol NA NA 19000 "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Vesicles, Centrosome" "CAB005865: AB_304116, HPA070398: , HPA071444: AB_2686396" "unprognostic (3.07e-2)" "unprognostic (6.36e-2)" "unprognostic (5.41e-2)" "unprognostic (8.05e-2)" "unprognostic (9.24e-2)" "unprognostic (1.43e-1)" "unprognostic (3.71e-3)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "unprognostic (1.52e-1)" "unprognostic (6.20e-3)" "unprognostic (7.23e-2)" "unprognostic (4.28e-3)" "unprognostic (2.44e-2)" "unprognostic (2.62e-1)" "unprognostic (9.45e-2)" "unprognostic (2.14e-2)" 24.6 29.0 41.4 14.5 50.8 16.6 25.4 41.4 60.5 29.8 34.1 34.9 15.7 39.3 5.2 42.1 38.4 6.2 46.9 41.9 40.3 38.8 37.9 23.9 12.3 40.3 41.8 34.3 27.4 18.9 26.8 8.3 38.6 29.3 6.7 7.3 25.2 10.4 46.9 33.7 24.0 8.0 39.2 21.0 28.9 32.5 39.6 9.6 27.1 16.9 8.1 33.3 29.7 39.5 86.9 150.0 27.1 38.6 15.3 14.3 78.8 44.3 17.8 45.0 38.3 85.5 57.7 56.1 42.1 24.3 27.0 59.0 33.1 43.9 11.6 48.4 270.8 74.9 48.2 79.7 34.1 72.3 38.1 18.5 39.4 44.6 20.9 19.4 22.5 46.5 61.6 31.1 15.8 80.3 65.4 64.2 95.6 75.2 125.8 63.7 41.7 121.0 30.4 54.8 71.0 108.0 54.2 54.2 46.9 14.4 41.7 56.4 29.8 50.3 55.0 29.4 83.1 48.4 126.9 60.0 57.6 62.6 56.6 2.0 25.7 7.2 39.1 45.4 40.9 53.9 42.2 44.7 52.9 64.3 42.1 41.1 1.7 44.2 39.6 29.3 43.3 25.1 41.4 50.8 41.4 60.5 41.9 40.3 40.3 41.8 38.6 39.2 39.6 39.5 11.8 9.6 11.5 5.5 15.6 26.8 39.7 55.5 29.6 15.9 20.1 20.8 13.2 34.3 35.1 35.0 6.2 48.0 11.6 46.4 72.4 62.5 13.4 69.4 15.2 18.5 22.6 18.1 8.6 46.1 57.0 22.0 25.5 13.4 10.8 20.0 10.4 23.9 39.1 13.5 11.6 31.7 44.7 11.3 13.7 16.0 19.6 11.9 17.8 3.7 28.2 14.9 21.6 6.0 7.3 42.6 44.4 17.7 27.3 29.5 25.5 62.5 119.8 14.8 26.3 24.2 31.9 39.0 28.8 27.9 29.5 37.5 17.1 16.6 58.9 35.2 HSPG2 "perlecan, PRCAN, SJS1" ENSG00000142798 "Heparan sulfate proteoglycan 2" P98160 1 21822244-21937310 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 366.8;Endothelial cells: 322.9;Granulosa cells: 776.0;Hepatic stellate cells: 600.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 293.0;HUVEC TERT2: 620.8;TIME: 504.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009820, HPA018892, CAB020718, HPA072690" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 1400000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB009820: AB_2119229, CAB020718: , HPA018892: AB_1850597, HPA072690: " "unprognostic (1.61e-1)" "unprognostic (1.57e-2)" "unprognostic (4.93e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (8.56e-2)" "unprognostic (4.55e-1)" "unprognostic (1.90e-2)" "unprognostic (9.35e-2)" "unprognostic (2.19e-3)" "unprognostic (5.82e-2)" "unprognostic (2.83e-1)" "unprognostic (1.21e-3)" "unprognostic (1.17e-2)" "unprognostic (4.86e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (2.82e-4)" 140.7 54.7 3.8 36.1 5.2 1.7 96.2 3.7 4.8 65.9 18.8 153.1 18.3 151.9 6.6 44.1 85.0 53.4 156.6 3.6 2.9 37.6 10.6 49.0 14.2 5.6 4.6 31.3 31.7 13.1 11.8 30.3 5.7 60.3 8.6 0.3 45.0 56.5 65.1 41.0 54.9 96.2 4.0 37.4 76.1 9.0 7.6 6.7 69.1 40.8 3.5 110.2 59.7 4.7 44.0 40.7 13.8 45.9 131.0 99.4 51.5 70.2 17.8 21.1 18.7 50.5 86.7 3.3 293.0 112.9 0.8 26.9 3.1 31.9 5.4 0.6 4.3 15.7 46.0 35.7 27.0 0.0 4.1 61.6 9.4 19.9 6.0 28.1 620.8 0.3 21.4 5.7 32.4 11.8 0.0 20.0 11.7 19.6 17.9 6.3 87.8 6.1 35.1 6.5 1.3 4.1 51.4 20.0 28.7 14.0 8.1 7.2 504.3 41.1 51.8 29.7 2.3 0.5 7.3 2.6 9.7 0.1 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 5.2 3.7 4.8 3.6 2.9 5.6 4.6 5.7 4.0 7.6 4.7 366.8 70.5 28.6 3.6 3.9 26.4 13.5 81.1 21.1 0.6 6.2 21.5 5.8 38.6 30.3 92.0 0.0 11.0 3.4 52.9 0.0 76.1 1.4 24.2 47.7 322.9 2.4 22.9 0.8 25.0 89.0 141.3 62.2 39.8 23.4 776.0 600.4 6.6 6.8 3.3 0.8 12.6 16.2 22.1 19.2 5.8 75.2 4.6 60.5 15.9 1.8 1.6 0.0 2.5 4.3 87.5 29.9 69.2 4.6 19.3 19.2 0.9 28.7 0.6 32.9 82.5 69.8 0.3 4.8 10.0 17.8 9.3 5.0 83.3 20.1 11.8 HTATIP2 "CC3, FLJ26963, SDR44U1, TIP30" ENSG00000109854 "HIV-1 Tat interactive protein 2" Q9BUP3 11 20363685-20383782 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Differentiation, Host-virus interaction" "Developmental protein, Oxidoreductase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 269.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 283.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006417, HPA024321" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA006417: AB_1079091, HPA024321: AB_1851288" "unprognostic (8.05e-3)" "unprognostic (2.13e-1)" "unprognostic (9.31e-2)" "unprognostic (3.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.79e-3)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.20e-3)" "unprognostic (1.05e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.20e-1)" "unprognostic (9.42e-2)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" 30.0 57.5 29.6 32.3 35.9 18.6 29.6 33.2 46.1 24.2 34.7 88.4 135.9 13.8 31.4 50.0 13.5 44.8 21.2 29.2 31.3 32.6 97.8 39.1 28.5 34.1 31.7 16.2 26.7 27.8 39.9 28.5 34.6 22.4 80.7 1.9 35.0 20.6 46.2 36.0 121.4 14.4 32.3 38.6 75.4 21.4 32.3 20.2 51.3 21.3 27.4 37.7 35.4 45.8 109.6 177.5 3.9 0.2 52.5 39.4 38.7 46.4 45.8 35.3 41.8 103.2 93.8 24.8 93.1 58.3 136.6 149.7 0.0 28.2 33.9 283.9 21.4 30.8 170.1 0.2 125.3 11.3 139.6 57.3 196.0 28.7 44.5 0.0 102.2 0.0 76.8 31.6 66.3 102.0 0.4 7.0 56.5 193.2 87.1 23.2 0.3 89.8 48.1 60.1 47.2 0.5 150.9 59.1 73.6 18.0 123.7 57.0 125.4 25.1 54.8 51.0 1.2 33.5 44.7 0.6 0.4 76.9 111.4 233.4 133.3 171.1 64.3 126.4 73.4 65.9 74.1 69.2 76.9 76.4 63.9 62.7 304.1 64.5 135.2 23.2 140.9 116.7 29.6 35.9 33.2 46.1 29.2 31.3 34.1 31.7 34.6 32.3 32.3 45.8 49.2 25.6 9.6 3.9 28.0 36.3 60.0 74.2 67.2 1.0 32.9 26.7 11.6 102.9 43.7 47.8 0.0 53.7 16.7 175.6 31.3 91.4 51.1 19.3 6.1 29.5 24.1 28.8 12.9 72.3 118.0 23.8 49.5 34.5 22.9 22.7 33.2 77.5 82.8 3.3 9.1 100.3 105.8 54.0 27.6 59.5 19.9 61.3 44.4 8.4 114.6 9.5 39.1 3.5 40.2 94.7 157.3 9.4 21.4 65.2 269.7 69.0 37.4 1.7 13.1 19.2 28.5 45.5 21.5 87.2 42.1 61.6 33.4 13.2 87.8 62.7 HTN1 HIS1 ENSG00000126550 "Histatin 1" P15515 4 70050438-70058848 "Predicted secreted proteins, Transporters" Biomineralization "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2602 "salivary gland: 48372.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077315 Approved "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 11: Alveolar cells - Smell perception" "HPA077315: " "unprognostic (2.22e-1)" 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 18.5 0.0 0.0 5.5 0.0 0.0 0.0 0.0 48372.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 HTN3 HIS2 ENSG00000205649 "Histatin 3" P15516 4 70028455-70036538 "Predicted secreted proteins, Transporters" Biomineralization "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1102 "salivary gland: 136053.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "melanoma: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.6;HL-60: 1.7" CAB073541 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB073541: " 0.0 0.1 0.7 0.3 1.3 18.9 0.1 2.8 2.3 0.0 0.0 2.4 0.3 0.2 0.4 0.2 0.1 0.1 26.2 0.9 0.0 0.1 0.1 0.2 0.3 0.1 0.0 26.0 123.4 0.1 1.8 13.1 0.2 0.2 3.0 0.7 136053.4 0.1 0.1 10.0 0.1 0.1 0.0 0.2 0.3 0.5 0.1 0.0 0.2 0.0 0.1 0.1 0.0 1.5 0.4 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.5 0.6 0.2 0.0 0.2 0.2 0.0 0.1 0.0 1.6 0.2 0.1 0.3 0.1 0.0 1.7 1.1 0.1 0.0 0.0 0.0 0.2 0.2 0.3 0.1 0.7 0.2 0.2 0.4 0.9 0.4 0.1 0.4 1.0 0.2 0.1 0.1 0.1 0.6 0.4 0.4 0.2 0.3 0.3 0.7 0.4 0.0 0.3 0.6 0.4 0.3 0.5 0.9 0.2 0.3 0.5 0.8 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.7 1.3 2.8 2.3 0.9 0.0 0.1 0.0 0.2 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269754-8307098 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 194.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 158.8;Leydig cells: 43.5;Peritubular cells: 42.9;Skeletal myocytes: 99.0;Theca cells: 25.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 67.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "U-2197: 182.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA021187: AB_1851311, HPA063810: AB_2685129" "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.34e-2)" 68.0 6.0 0.9 8.7 1.3 13.4 50.4 0.9 1.3 35.4 5.0 33.9 8.7 42.4 10.6 15.1 26.2 35.5 194.9 0.9 1.0 6.2 3.2 38.0 1.2 1.0 1.0 93.0 6.8 0.4 15.7 20.4 1.0 26.3 4.8 0.1 22.8 6.7 32.1 28.1 16.9 11.8 1.0 2.9 21.9 4.3 1.7 2.2 26.0 12.9 0.7 62.4 32.6 0.7 0.0 1.0 1.4 0.0 5.8 10.8 0.3 2.4 0.2 2.8 0.6 0.1 0.1 0.0 13.6 6.4 1.4 0.1 1.2 0.0 0.9 0.0 2.3 1.3 13.9 0.0 6.1 0.0 0.6 1.2 0.0 4.2 0.0 1.7 9.8 0.0 0.3 0.0 10.2 0.0 0.2 36.5 6.1 0.0 0.3 0.3 0.0 0.1 0.0 0.0 15.8 0.3 26.4 0.5 0.2 28.8 0.1 1.1 8.1 1.4 4.7 182.1 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 1.3 0.9 1.3 0.9 1.0 1.0 1.0 1.0 1.0 1.7 0.7 12.6 0.0 0.0 0.0 0.0 5.2 0.5 0.0 0.6 0.0 0.5 0.9 16.5 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.0 0.1 1.2 0.3 8.1 5.3 0.0 0.0 0.0 0.0 4.2 158.8 0.5 0.3 0.0 6.0 3.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 8.6 1.4 43.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.9 0.4 0.4 0.0 0.1 0.0 0.0 0.0 99.0 10.6 0.4 0.7 0.6 5.3 1.4 0.9 25.2 0.0 0.2 HTRA4 FLJ90724 ENSG00000169495 "HtrA serine peptidase 4" P83105 8 38974228-38988663 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 67.0" "Cell type enriched" "Detected in some" 10 "Extravillous trophoblasts: 444.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "BEWO: 233.6" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in all" HPA045402 Enhanced "Secreted in female reproductive system" NA NA 23000 "Cluster 17: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA045402: AB_2679316" "unprognostic (1.20e-1)" "unprognostic (5.83e-4)" "unprognostic (8.02e-2)" "unprognostic (2.13e-2)" "unprognostic (8.20e-2)" "unprognostic (2.42e-2)" "unprognostic (1.80e-1)" "unprognostic (7.40e-3)" "unprognostic (1.40e-1)" "unprognostic (5.14e-4)" "unprognostic (1.01e-1)" "unprognostic (8.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.58e-1)" "unprognostic (5.19e-3)" "unprognostic (2.39e-3)" "unprognostic (1.19e-3)" 0.8 0.5 0.8 0.8 1.2 7.2 1.2 3.5 5.0 0.9 0.0 0.5 0.3 0.9 0.9 0.1 0.3 0.5 0.3 1.3 0.9 0.4 0.5 2.0 2.5 0.6 0.5 0.6 0.8 0.5 0.1 67.0 0.6 0.6 0.7 1.8 0.3 1.1 1.0 0.8 0.4 0.7 0.1 1.2 0.4 0.9 1.4 0.5 0.5 0.1 1.7 0.4 0.1 2.0 0.4 0.3 0.2 0.4 0.8 0.4 233.6 0.6 0.4 0.3 0.4 0.4 0.5 0.5 0.2 0.2 0.4 0.4 0.2 0.2 0.1 0.2 0.4 0.4 0.7 0.3 0.2 0.6 0.6 0.7 0.2 0.2 0.5 0.3 0.2 0.2 0.4 1.3 0.2 0.5 0.4 0.3 0.3 0.1 0.2 0.2 0.2 0.4 0.2 0.7 0.4 0.6 0.5 0.3 0.1 9.6 0.5 0.7 0.0 0.7 0.5 0.3 0.3 0.5 0.2 0.2 0.2 0.7 0.2 0.3 0.1 0.4 0.2 0.1 0.3 0.2 0.2 0.2 0.1 0.5 0.2 0.2 0.5 0.2 0.2 0.5 0.3 0.0 0.8 1.2 3.5 5.0 1.3 0.9 0.6 0.5 0.6 0.1 1.4 2.0 0.1 0.0 0.0 0.0 1.0 0.1 1.7 0.1 1.2 0.5 0.1 0.3 0.7 0.0 0.0 0.0 2.1 2.8 1.1 0.1 0.0 0.0 0.1 0.2 0.7 0.3 0.0 0.0 0.4 0.0 444.0 1.2 0.0 0.5 0.0 0.7 1.4 0.0 11.6 1.7 0.2 0.0 0.0 0.6 0.3 0.0 0.0 3.8 1.8 1.0 0.0 0.4 1.0 1.5 0.2 0.3 0.0 0.0 0.5 1.5 0.0 0.2 0.1 0.2 0.0 3.5 0.2 0.0 0.1 0.0 0.1 40.4 0.7 0.2 0.2 1.1 HYAL1 "HYAL-1, LUCA1" ENSG00000114378 "Hyaluronidase 1" Q12794 3 50299890-50312381 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 201.6;lymphoid tissue: 95.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Hepatic stellate cells: 33.2;Hepatocytes: 137.1;Proximal tubular cells: 58.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Hep G2: 100.9;SK-BR-3: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" NA NA 590000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favorable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favorable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" 11.4 21.5 5.0 2.8 4.5 0.3 9.2 6.4 6.3 10.8 18.3 6.8 3.4 8.2 0.8 5.5 7.3 13.2 68.2 4.5 4.0 49.4 201.6 30.7 1.8 5.4 4.8 3.0 9.4 19.9 3.3 2.4 5.6 4.6 2.9 3.1 7.3 2.9 15.0 21.1 6.0 5.9 3.5 95.1 19.4 1.7 5.8 0.8 8.3 19.0 1.2 4.8 12.3 4.7 2.9 1.8 0.4 0.9 0.6 0.7 0.5 0.1 0.3 0.1 0.4 11.4 3.1 0.0 0.8 0.6 0.6 6.6 0.2 0.4 0.0 0.1 0.0 0.3 8.6 100.9 4.4 0.7 0.7 3.9 13.8 0.1 0.4 0.8 2.9 0.3 0.3 0.5 0.4 0.6 0.1 0.3 0.6 7.1 0.6 0.0 0.2 0.3 5.9 0.4 0.2 2.1 0.2 28.0 0.3 2.4 2.0 0.3 1.9 0.6 0.6 0.6 0.3 0.2 0.3 0.4 0.4 0.6 0.3 1.3 0.4 1.5 0.3 0.1 0.8 0.4 0.3 0.4 0.2 0.5 0.6 0.4 3.1 0.3 0.3 0.5 0.4 0.1 5.0 4.5 6.4 6.3 4.5 4.0 5.4 4.8 5.6 3.5 5.8 4.7 18.1 19.2 18.5 1.6 0.3 2.9 0.4 3.3 0.0 1.0 0.3 0.1 20.8 30.0 2.0 11.0 4.2 0.1 0.0 2.5 23.5 16.5 8.2 0.2 0.9 25.8 1.8 2.7 3.1 14.4 0.1 3.3 19.4 0.2 0.0 0.6 33.2 137.1 0.1 0.0 3.1 1.4 0.0 4.4 0.9 7.7 2.1 0.9 0.0 7.5 0.0 0.4 0.0 1.5 1.6 12.1 0.3 1.2 0.0 0.2 0.4 58.2 0.9 0.5 6.6 1.2 4.3 0.4 1.1 0.9 3.1 0.7 0.9 7.4 0.9 1.7 HYAL2 "LuCa-2, LUCA2" ENSG00000068001 "Hyaluronidase 2" Q12891 3 50317790-50322782 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 282.8" "Group enriched" "Detected in many" 5 "Adipocytes: 497.6;Endothelial cells: 216.3;Hepatic stellate cells: 253.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "HUVEC TERT2: 363.3;TIME: 502.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036436 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA036436: AB_10670104" "unprognostic (9.97e-3)" "unprognostic (2.60e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-3)" "unprognostic (3.44e-1)" "unprognostic (7.41e-2)" "unprognostic (7.93e-2)" "unprognostic (4.70e-1)" "unprognostic (1.44e-1)" "unprognostic (6.76e-2)" "unprognostic (2.36e-1)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (7.36e-2)" "unprognostic (2.72e-1)" "unprognostic (7.02e-3)" "unprognostic (5.62e-2)" 97.4 62.6 24.7 29.1 23.0 3.1 93.9 24.9 28.3 51.6 24.3 34.0 17.9 66.1 10.3 39.7 55.6 47.5 92.2 22.3 24.8 85.1 32.2 186.8 40.0 26.0 24.9 29.1 27.9 25.7 41.6 87.4 27.5 37.2 11.5 3.3 37.5 22.0 30.9 37.1 38.7 37.4 27.1 282.8 38.6 22.0 28.1 9.5 80.9 35.7 14.6 47.0 45.8 24.9 26.8 38.5 63.0 64.1 38.2 32.9 39.6 29.8 41.2 42.0 32.6 44.6 77.3 7.0 102.4 43.6 82.5 27.4 24.6 58.7 12.0 14.2 19.6 9.7 34.9 69.2 33.0 8.1 24.4 51.9 48.8 42.1 13.8 38.1 363.3 18.2 17.6 8.0 35.4 37.0 17.7 16.6 72.0 23.2 55.7 15.5 12.4 26.1 52.4 24.2 16.6 53.3 30.4 31.2 31.8 21.2 34.4 20.3 502.9 50.0 49.7 33.5 47.5 13.9 24.1 21.6 29.4 25.5 73.0 0.0 9.5 10.7 1.4 14.1 3.0 1.1 1.3 3.8 5.3 1.5 0.4 0.7 9.2 2.8 13.6 4.0 1.9 3.3 24.7 23.0 24.9 28.3 22.3 24.8 26.0 24.9 27.5 27.1 28.1 24.9 497.6 19.2 9.9 5.2 3.6 13.0 28.6 45.2 11.4 7.8 17.6 16.6 7.3 32.9 30.9 33.1 6.2 33.6 4.1 13.5 11.7 53.0 4.7 8.5 19.8 216.3 7.3 10.1 1.6 38.7 38.4 26.6 16.8 13.8 0.0 31.5 253.1 9.1 46.2 8.4 1.9 13.0 42.7 12.6 9.3 5.0 24.5 9.4 17.8 15.9 7.6 19.7 5.2 4.0 3.4 45.6 13.5 22.2 4.2 45.3 16.1 11.8 11.0 6.1 39.5 11.2 26.0 11.2 56.0 24.9 12.6 32.7 4.1 50.0 16.6 33.3 HYAL3 "LUCA-3, LUCA14, Minna14" ENSG00000186792 "Hyaluronidase 3" O43820 3 50292831-50299405 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.4" "Group enriched" "Detected in many" 17 "Early spermatids: 79.7;Late spermatids: 268.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 33.2;eosinophil: 54.6" "Lineage enriched" "Detected in all" 7 "granulocytes: 54.6" "Cell line enhanced" "Detected in all" "HEL: 58.8;HMC-1: 101.1;THP-1: 107.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA049402 Uncertain "Secreted to blood" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA049402: AB_2680746" "unprognostic (1.21e-3)" "unprognostic (2.55e-2)" "unprognostic (5.45e-2)" "unprognostic (8.19e-2)" "unprognostic (3.07e-1)" "unprognostic (1.65e-2)" "unprognostic (7.98e-3)" "unprognostic (7.36e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-2)" "unprognostic (5.40e-2)" "unprognostic (5.71e-2)" "unprognostic (2.61e-1)" "unprognostic (8.09e-2)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.12e-5)" 2.1 2.8 5.1 1.3 5.4 36.4 1.8 6.7 8.3 2.0 2.9 1.9 1.7 1.6 1.1 3.9 1.6 1.8 1.8 5.1 4.0 2.6 5.1 2.1 1.2 7.4 4.0 1.5 1.9 0.9 1.9 1.5 7.3 3.2 1.0 1.1 3.5 2.4 1.0 2.1 1.8 2.2 3.9 1.7 4.5 13.9 5.4 1.6 1.7 0.9 1.6 1.8 2.7 5.8 6.0 6.9 3.8 4.3 7.6 3.9 2.3 6.5 5.8 8.0 6.1 9.3 6.2 5.2 3.1 7.5 12.4 6.5 7.0 15.2 3.0 12.3 3.6 58.8 18.8 7.6 5.5 6.4 101.1 8.1 11.5 8.1 5.2 5.8 8.4 5.8 4.6 6.3 3.8 3.6 2.4 37.4 2.9 7.0 17.2 2.6 5.1 9.5 9.5 2.6 4.7 5.4 9.6 7.5 5.1 4.4 4.9 107.2 11.1 6.8 4.9 22.2 3.8 3.0 7.0 4.4 6.0 22.5 5.8 33.2 4.1 54.6 1.3 2.3 2.2 1.6 4.1 1.9 8.2 2.9 1.1 1.5 1.4 2.1 1.4 2.0 2.6 2.4 5.1 5.4 6.7 8.3 5.1 4.0 7.4 4.0 7.3 3.9 5.4 5.8 2.5 3.2 1.1 0.3 0.8 3.1 2.8 8.1 2.8 1.5 2.2 2.8 0.4 1.5 5.0 3.7 4.2 2.8 0.2 0.8 9.8 5.6 79.7 2.0 1.6 3.5 4.2 9.2 2.4 0.7 5.3 1.2 4.1 2.1 7.0 1.1 7.1 2.1 2.1 5.0 1.6 1.9 6.1 1.9 4.4 268.2 1.8 2.0 3.6 1.0 5.9 1.5 0.0 0.5 0.3 3.6 0.4 2.6 1.9 2.2 0.5 2.7 1.8 0.8 6.6 1.2 1.8 4.3 4.6 3.7 3.7 3.0 2.2 1.6 1.8 3.5 HYAL4 ENSG00000106302 "Hyaluronidase 4" Q2M3T9 7 123828983-123877481 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 4.0;skeletal muscle: 3.9" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.8;Cytotrophoblasts: 4.3;Extravillous trophoblasts: 8.1;Spermatogonia: 4.4;Syncytiotrophoblasts: 2.2" "Cancer enriched" "Detected in single" 48 "testis cancer: 8.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.6;CAPAN-2: 5.9;RT4: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA029453 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA029453: AB_10601432" "unprognostic (5.19e-5)" "unprognostic (4.18e-2)" "unprognostic (4.82e-2)" "unprognostic (2.20e-1)" "unprognostic (4.14e-2)" "unprognostic (2.60e-1)" "unprognostic (8.24e-2)" "unprognostic (5.26e-2)" "unprognostic (8.15e-3)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.19e-1)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (5.55e-3)" 0.1 0.1 0.6 0.0 0.7 0.5 0.1 1.0 1.0 0.1 0.5 0.2 0.0 0.1 0.4 0.4 0.0 0.1 0.2 0.7 0.4 0.4 0.1 0.4 0.2 0.5 0.3 0.2 0.5 0.0 0.0 4.0 0.7 0.2 0.1 1.0 0.5 0.2 3.9 0.9 0.2 0.0 0.1 0.8 0.2 2.1 0.5 0.0 0.4 0.0 1.0 0.2 0.0 1.3 0.2 0.4 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 5.9 0.2 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.1 0.0 13.9 0.2 0.0 0.0 0.8 0.0 1.1 0.2 0.0 2.0 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.6 0.2 0.1 0.1 0.0 0.0 0.6 0.7 1.0 1.0 0.7 0.4 0.5 0.3 0.7 0.1 0.5 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 8.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 1.3 4.4 0.0 0.0 2.2 0.0 0.0 0.0 0.2 HYOU1 "Grp170, HSP12A, ORP150" ENSG00000149428 "Hypoxia up-regulated 1" Q9Y4L1 11 119044188-119057227 "Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Stress response" Chaperone "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 201.9" "Cell type enhanced" "Detected in all" "Plasma cells: 118.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 35.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 418.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049296 Approved "Intracellular and membrane" NA NA 130000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA049296: AB_2680702" "unprognostic (2.97e-2)" "unprognostic (2.48e-2)" "unprognostic (8.46e-2)" "prognostic favorable (2.58e-4)" "unprognostic (2.19e-1)" "unprognostic (1.35e-2)" "unprognostic (1.61e-3)" "unprognostic (1.81e-1)" "unprognostic (8.98e-2)" "unprognostic (7.93e-2)" "unprognostic (2.01e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (5.10e-5)" "unprognostic (3.86e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.38e-2)" 38.2 48.5 30.7 27.1 32.2 18.6 31.0 28.3 34.1 37.2 25.5 40.9 18.1 44.6 51.2 47.4 40.8 14.0 56.5 32.9 41.0 63.0 201.9 47.7 17.4 32.6 34.5 36.1 165.9 18.8 100.1 19.9 34.2 47.9 21.3 11.9 46.3 20.7 19.1 25.0 39.0 19.0 28.5 47.6 60.3 85.7 35.2 21.7 87.2 8.4 20.9 39.9 31.7 32.9 40.5 34.5 77.2 224.4 41.2 19.7 107.7 56.1 38.0 63.1 47.2 105.0 103.0 85.3 418.9 40.7 122.1 59.5 71.5 69.3 53.8 92.8 26.1 151.8 32.6 76.7 187.7 88.6 73.5 23.9 91.1 55.2 185.3 57.9 100.2 57.2 53.5 136.8 33.9 97.8 59.4 49.6 55.5 83.2 33.6 63.1 55.9 144.3 48.6 67.8 45.7 70.0 80.4 103.8 53.3 65.5 78.8 82.9 75.0 59.9 46.4 27.2 77.5 88.1 64.0 61.2 53.8 76.2 135.6 4.4 4.5 2.2 11.7 6.1 12.6 5.4 6.4 8.7 5.0 4.0 4.0 6.1 1.3 7.6 4.4 35.9 5.5 4.7 30.7 32.2 28.3 34.1 32.9 41.0 32.6 34.5 34.2 28.5 35.2 32.9 16.4 9.6 14.1 6.2 22.7 17.8 18.5 17.5 14.2 11.5 28.5 21.1 12.4 15.7 16.8 25.8 43.8 11.2 36.6 35.3 9.8 20.7 74.0 20.4 29.1 20.0 35.8 17.0 12.0 18.8 26.6 21.0 39.8 38.1 15.8 43.1 13.9 49.9 22.2 25.2 13.7 52.1 18.3 8.2 21.6 38.8 13.1 17.8 23.2 5.6 15.5 8.7 17.5 4.5 9.3 31.4 24.2 13.5 118.7 44.4 14.9 17.6 16.7 14.5 13.1 16.4 15.6 27.8 29.1 16.2 19.9 19.3 20.8 14.8 27.3 24.7 IAPP "AMYLIN, DAP, IAP" ENSG00000121351 "Islet amyloid polypeptide" P10997 12 21354959-21379980 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "pancreas: 166.7" "Group enriched" "Detected in some" 5 "Early spermatids: 44.5;Pancreatic endocrine cells: 15.2" "Cancer enriched" "Detected in single" 76 "pancreatic cancer: 21.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000352, HPA053194" Enhanced Approved Vesicles "Secreted to blood" NA NA 11900 "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "CAB000352: AB_2121635, HPA053194: AB_2682076" "unprognostic (5.52e-3)" "unprognostic (1.00e-1)" "unprognostic (4.16e-1)" "unprognostic (1.74e-1)" "unprognostic (1.91e-1)" 0.5 0.0 0.1 0.0 0.2 1.0 0.0 0.5 0.3 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 2.3 0.0 0.2 0.1 0.5 0.0 166.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 3.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.1 0.3 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.5 0.3 0.1 0.2 0.1 0.5 0.2 0.0 0.8 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 44.5 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.9 0.3 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 1.5 0.3 0.3 0.2 0.0 0.4 0.3 0.3 0.1 0.0 0.8 IBSP "BSP, BSP-II, SP-II" ENSG00000029559 "Integrin binding sialoprotein" P21815 4 87799554-87812435 "Cancer-related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;pituitary gland: 2.0" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 5.8" "Group enriched" "Detected in many" 4 "breast cancer: 3.8;glioma: 12.2" "Region enhanced" "Detected in single" "thalamus: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-138 MG: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.53e-2)" "unprognostic (3.55e-2)" "unprognostic (1.49e-2)" "unprognostic (3.93e-1)" "unprognostic (3.75e-2)" "unprognostic (9.48e-3)" "unprognostic (1.03e-3)" "unprognostic (4.07e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-11)" "unprognostic (6.20e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-3)" "unprognostic (2.11e-1)" 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 2.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.5 0.7 0.7 0.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ICAM1 "BB2, CD54" ENSG00000090339 "Intercellular adhesion molecule 1" P05362 19 10271093-10286615 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 219.3;urinary bladder: 215.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 612.2;Alveolar cells type 2: 561.6;Endothelial cells: 240.8;Langerhans cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 158.3;Karpas-707: 459.7;RPMI-8226: 148.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002126, CAB002142, HPA004877" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA 87900000 2200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Vesicles, Cytosol" "CAB002142: AB_563596, HPA002126: AB_1078470, HPA004877: AB_1846317" "prognostic favorable (7.09e-4)" "unprognostic (1.88e-1)" "unprognostic (1.94e-1)" "unprognostic (2.63e-2)" "unprognostic (3.25e-3)" "unprognostic (3.05e-1)" "unprognostic (1.45e-2)" "unprognostic (3.48e-1)" "unprognostic (3.18e-2)" "unprognostic (1.09e-2)" "unprognostic (1.49e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.32e-6)" "unprognostic (2.77e-1)" "unprognostic (2.16e-2)" "unprognostic (2.25e-1)" "unprognostic (3.70e-3)" 87.9 23.6 9.1 44.6 9.6 117.1 32.4 7.9 12.0 11.2 9.9 17.7 16.8 23.9 3.5 11.0 26.2 56.4 39.1 8.8 9.9 43.9 67.1 219.3 38.3 12.3 8.7 13.0 11.1 8.3 9.3 27.8 10.2 22.2 18.1 10.5 18.0 6.3 15.1 17.9 22.6 23.4 10.0 55.9 21.5 5.6 15.4 28.4 30.8 12.8 32.9 215.3 12.5 10.2 46.3 0.5 7.9 0.2 2.0 4.4 9.7 8.6 91.6 21.8 62.0 14.0 49.8 39.6 130.3 3.8 99.3 8.9 1.7 0.4 45.6 123.8 0.1 3.8 1.4 62.0 158.3 1.3 23.9 55.7 4.0 13.7 20.3 2.0 10.7 4.9 15.0 459.7 1.5 3.3 0.5 34.9 3.1 0.5 24.7 1.0 0.2 148.5 36.8 0.3 0.3 1.1 61.2 3.3 94.5 3.7 6.9 2.8 34.3 22.3 1.9 12.3 0.8 137.4 142.7 25.5 35.1 26.3 32.6 5.0 28.3 5.2 5.3 25.8 9.8 3.8 4.0 6.3 24.7 1.5 1.9 3.8 40.8 15.2 17.0 14.1 6.1 20.8 9.1 9.6 7.9 12.0 8.8 9.9 12.3 8.7 10.2 10.0 15.4 10.2 150.3 612.2 561.6 0.3 31.7 85.3 22.2 62.6 28.5 0.0 50.2 24.9 1.1 21.5 133.5 3.7 0.0 1.1 28.9 2.9 0.0 176.8 2.0 14.1 15.5 240.8 2.4 1.3 0.5 98.7 3.3 136.6 13.7 29.8 139.8 0.1 48.2 12.1 86.7 0.0 0.4 0.7 32.6 53.6 232.6 1.3 4.7 168.3 76.5 7.5 101.9 4.6 5.2 0.5 0.2 113.7 0.3 1.5 57.6 27.1 0.3 15.0 83.2 0.4 6.6 38.2 57.6 0.8 1.6 4.3 69.3 1.2 28.8 0.5 1.6 14.1 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 ICAM4 "CD242, LW" ENSG00000105371 "Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)" Q14773 19 10286955-10288522 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Blood group antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 13.4;lung: 9.3" "Cell type enhanced" "Detected in many" "Adipocytes: 24.9;Alveolar cells type 1: 67.3;Alveolar cells type 2: 76.5;Erythroid cells: 46.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 6 "non-classical monocyte: 215.4" "Lineage enriched" "Detected in many" 7 "monocytes: 215.4" "Cell line enhanced" "Detected in some" "HEL: 71.0;HMC-1: 17.1;K-562: 37.4;NB-4: 30.7;U-937: 17.1" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 11: Alveolar cells - Smell perception" 0.9 0.3 0.3 0.8 0.4 13.4 0.4 0.3 1.0 0.2 0.0 0.7 0.9 0.3 0.2 0.3 0.4 1.1 0.6 0.3 0.0 0.3 0.8 9.3 1.0 0.6 0.0 0.5 0.1 0.3 0.1 1.8 0.3 0.7 0.5 0.7 1.0 0.4 0.4 0.5 0.9 0.4 0.0 1.2 1.5 0.3 0.1 1.1 0.3 0.1 1.4 1.8 0.2 0.5 0.2 0.1 0.3 0.4 0.0 0.0 5.9 0.6 0.2 0.0 0.0 7.8 0.4 0.8 0.8 0.0 0.3 0.6 0.1 0.1 0.1 0.6 0.2 71.0 0.6 10.6 1.9 1.2 17.1 0.4 0.0 0.2 0.2 0.0 0.1 11.2 37.4 3.1 0.1 0.2 2.0 30.7 0.2 0.0 0.3 5.2 2.9 13.6 0.1 0.3 0.1 0.2 0.6 0.1 0.3 0.8 0.2 2.1 0.4 0.2 0.1 0.5 0.0 1.0 2.0 0.2 0.6 17.1 0.4 24.0 10.0 10.2 0.9 38.5 1.8 2.2 1.1 0.8 30.8 2.2 1.3 0.3 2.3 0.5 215.4 10.2 2.6 9.1 0.3 0.4 0.3 1.0 0.3 0.0 0.6 0.0 0.3 0.0 0.1 0.5 24.9 67.3 76.5 0.3 2.3 1.0 1.9 8.0 1.2 0.0 4.9 3.6 0.0 0.0 21.0 0.0 0.0 0.3 3.0 0.4 0.0 0.6 0.0 2.9 2.0 18.3 0.0 46.7 0.0 2.1 0.6 10.3 1.5 5.6 22.1 0.0 2.5 0.2 5.6 0.0 0.0 0.0 0.0 5.5 6.9 0.0 0.0 16.8 5.4 0.0 14.6 0.2 0.0 0.0 0.0 0.9 0.0 0.0 17.5 1.4 0.0 0.1 4.4 0.1 0.0 9.1 3.3 0.0 1.0 0.7 1.3 0.8 1.8 0.2 0.0 2.4 ID1 "bHLHb24, dJ857M17.1.2" ENSG00000125968 "Inhibitor of DNA binding 1, HLH protein" P41134 20 31605283-31606515 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1667.3;Basal respiratory cells: 1443.4;Hepatic stellate cells: 2131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 509.6;HaCaT: 500.2;Hep G2: 425.3;PC-3: 515.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025915, HPA051456, HPA058518" Approved Enhanced Nucleoplasm "Intracellular and membrane" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB025915: , HPA051456: AB_2681492, HPA058518: AB_2683740" "unprognostic (3.89e-2)" "unprognostic (3.45e-2)" "unprognostic (2.62e-2)" "unprognostic (3.19e-2)" "unprognostic (1.27e-2)" "unprognostic (1.74e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (4.85e-4)" "unprognostic (2.29e-1)" "unprognostic (1.58e-1)" "unprognostic (2.14e-2)" "unprognostic (7.83e-2)" "unprognostic (1.67e-2)" "unprognostic (1.71e-3)" "unprognostic (2.97e-1)" "unprognostic (6.17e-3)" "unprognostic (3.41e-3)" 242.2 88.5 53.0 20.2 43.1 9.0 141.3 50.1 57.1 125.7 60.9 136.7 78.4 116.0 4.7 340.4 146.3 35.0 291.9 45.3 56.8 218.1 154.1 204.7 14.0 69.3 56.0 66.8 42.4 8.1 167.8 45.7 62.3 202.5 26.4 5.1 58.5 149.6 53.8 129.6 154.3 12.2 53.3 79.7 162.5 16.4 79.1 5.9 266.8 37.8 6.2 351.1 206.9 47.1 76.1 245.3 2.7 49.3 31.2 14.1 187.6 314.1 12.6 56.9 6.2 130.5 111.4 0.6 509.6 84.3 67.2 500.2 40.1 17.9 8.6 6.2 25.6 41.5 229.2 425.3 42.3 0.9 2.2 57.4 69.7 0.3 4.3 93.5 35.0 27.6 94.0 2.3 110.4 99.8 11.4 1.8 172.7 336.5 515.3 0.9 200.8 4.2 11.1 206.1 93.5 87.4 261.3 91.9 2.4 128.8 57.0 7.6 188.5 151.3 300.0 49.0 216.1 5.6 6.3 5.2 176.2 39.5 21.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 0.2 0.0 0.0 0.1 53.0 43.1 50.1 57.1 45.3 56.8 69.3 56.0 62.3 53.3 79.1 47.1 1667.3 237.2 171.7 88.2 25.1 102.3 992.2 1443.4 406.3 2.7 98.6 114.3 35.1 112.9 685.1 228.1 4.2 129.9 46.3 594.3 37.2 584.1 5.7 794.1 450.1 907.7 572.7 49.9 0.6 535.5 493.7 195.3 675.3 707.6 22.2 8.9 2131.4 109.1 25.6 0.0 0.5 557.4 321.4 72.2 52.4 8.7 28.6 38.9 90.7 92.8 8.2 85.0 1.0 4.0 0.3 257.4 924.9 0.4 26.7 519.7 579.8 7.1 168.1 8.3 13.1 229.7 206.1 3.2 53.7 455.8 87.9 89.1 39.8 15.9 389.1 591.6 IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574096 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Secreted in other tissues" NA NA 310000 "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA063478: AB_2685020" "unprognostic (1.70e-1)" "unprognostic (6.40e-2)" "prognostic favorable (3.69e-4)" "prognostic favorable (3.53e-4)" "unprognostic (2.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (7.79e-2)" "unprognostic (6.81e-2)" "unprognostic (9.24e-3)" "unprognostic (6.13e-2)" "unprognostic (3.89e-2)" "unprognostic (3.91e-1)" 6.7 10.1 3.4 2.8 3.6 3.5 6.1 3.7 4.2 8.1 5.9 8.6 3.3 7.4 9.7 9.8 6.5 2.9 11.7 3.4 3.7 5.9 11.4 5.9 3.4 3.8 3.7 5.4 12.3 9.5 4.7 2.7 3.9 9.1 3.8 10.3 7.8 4.2 28.8 36.4 6.8 3.7 3.6 6.3 8.2 25.8 3.6 2.4 6.7 9.7 4.1 8.9 7.9 3.8 12.1 22.9 6.2 15.1 10.5 5.8 8.5 10.4 13.3 6.1 5.2 19.4 9.5 12.5 16.4 14.3 7.2 16.3 14.6 10.0 3.9 14.7 8.8 5.1 13.7 25.9 11.5 14.9 6.5 5.4 6.6 9.1 14.0 7.8 8.6 3.3 10.0 8.1 5.4 18.0 6.6 8.8 10.2 10.4 5.2 10.2 10.8 9.0 10.9 19.3 2.2 5.6 14.3 6.4 6.7 6.8 12.6 6.3 15.3 4.4 8.2 5.0 10.4 11.2 12.2 14.5 6.9 10.9 4.4 0.3 3.5 1.4 2.0 4.2 2.2 2.9 2.6 2.9 4.6 2.1 1.9 2.0 0.0 3.7 5.9 1.3 3.9 2.3 3.4 3.6 3.7 4.2 3.4 3.7 3.8 3.7 3.9 3.6 3.6 3.8 12.9 9.6 14.1 20.9 11.1 5.2 6.1 10.5 5.2 15.0 8.7 4.3 45.7 7.2 10.6 7.3 47.9 11.2 10.0 14.0 1.9 14.0 46.4 14.9 19.3 10.8 10.8 19.6 43.3 20.2 5.7 9.1 22.4 16.5 1.3 9.9 11.7 24.1 11.9 6.7 42.6 12.7 18.3 16.6 5.4 12.0 6.5 12.5 8.8 23.4 7.8 7.8 4.1 20.6 24.0 16.5 5.7 10.1 24.2 12.2 9.0 10.7 23.3 26.9 6.6 7.6 13.2 51.5 11.0 19.6 16.3 3.8 8.5 9.8 9.8 9.6 IDH2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2" P48735 15 90083045-90102477 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 492.6;skeletal muscle: 1302.3;tongue: 1611.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 732.5;Distal tubular cells: 1168.0;Extravillous trophoblasts: 586.7;Syncytiotrophoblasts: 573.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 425.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria NA NA 5200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA007831: AB_1851397" "unprognostic (2.45e-2)" "prognostic favorable (5.15e-5)" "unprognostic (2.92e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (8.46e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-3)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-3)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" 32.8 10.5 56.5 60.2 67.8 161.1 51.1 57.1 59.8 36.6 76.6 95.9 97.2 29.0 12.5 140.6 32.7 31.7 492.6 47.2 55.0 208.3 274.7 32.0 77.1 61.0 61.3 13.6 128.7 104.0 15.5 87.3 54.4 76.2 84.1 5.4 163.1 90.4 1302.3 61.8 84.3 79.8 52.9 36.8 175.7 5.3 71.6 148.7 16.0 1611.3 66.0 53.3 49.4 57.6 61.3 33.5 169.9 169.8 23.3 28.3 144.5 74.5 110.8 68.0 72.6 16.1 51.1 72.7 21.0 61.2 65.1 20.8 25.1 22.4 32.0 143.8 16.9 122.9 12.7 119.7 28.1 85.1 118.2 59.7 12.7 16.3 13.0 82.1 141.0 246.4 18.9 59.3 53.0 175.3 425.0 131.2 51.8 81.9 14.3 352.0 122.4 213.7 105.6 71.3 244.5 125.3 92.1 359.8 29.9 94.2 290.9 256.9 34.0 120.4 17.0 16.1 34.9 101.5 20.5 9.0 38.4 175.0 71.2 45.0 112.8 75.6 105.9 199.1 53.2 70.1 77.0 120.1 136.9 47.7 42.9 71.8 22.9 99.9 252.1 79.4 72.4 163.4 56.5 67.8 57.1 59.8 47.2 55.0 61.0 61.3 54.4 52.9 71.6 57.6 16.9 6.4 21.0 40.1 64.2 39.9 98.8 91.6 12.5 6.2 90.5 48.1 445.9 114.4 95.8 75.4 10.4 732.5 84.0 70.0 1168.0 252.8 5.6 96.4 25.7 41.6 61.7 193.8 11.8 288.8 586.7 44.7 88.2 50.9 31.6 29.2 38.2 283.1 263.7 10.1 8.3 158.3 229.9 77.7 101.1 3.2 14.0 79.0 58.7 5.6 85.3 20.9 119.4 16.6 27.3 116.6 105.0 35.3 185.9 170.3 69.6 205.0 167.9 5.4 13.1 60.8 73.4 0.6 15.6 113.3 67.1 573.0 88.1 14.7 305.1 140.1 IDH3G ENSG00000067829 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma" P51553 X 153785766-153794523 "Citric acid cycle related proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 284.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000425, HPA002017" Supported Approved Nucleoli,Mitochondria Yes No 19000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitochondria" "HPA000425: AB_1079097, HPA002017: AB_1079096" "unprognostic (4.24e-2)" "unprognostic (1.43e-3)" "unprognostic (5.75e-2)" "unprognostic (1.05e-1)" "unprognostic (6.57e-2)" "unprognostic (2.25e-1)" "unprognostic (4.35e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (1.59e-2)" "unprognostic (2.81e-2)" "unprognostic (1.96e-1)" "prognostic favorable (5.73e-6)" "unprognostic (1.50e-1)" "unprognostic (3.35e-1)" "unprognostic (2.91e-2)" "unprognostic (2.46e-1)" 52.0 67.1 45.5 38.5 50.0 60.3 49.9 47.8 61.3 44.1 46.5 57.2 52.3 50.7 23.5 50.2 44.8 35.0 91.9 54.9 48.8 68.5 49.2 42.0 40.3 50.5 45.7 49.3 48.3 45.5 47.9 28.3 52.3 43.8 34.6 24.4 51.7 39.9 100.5 51.7 54.7 34.5 43.9 51.8 52.2 32.1 49.1 35.2 48.0 82.9 34.9 44.3 43.2 47.2 94.9 90.0 47.3 65.9 74.4 59.4 62.0 47.3 64.1 80.5 84.3 76.0 66.5 121.4 80.2 74.7 68.2 67.2 72.6 69.2 30.0 38.9 101.7 43.0 118.9 59.0 85.5 61.6 87.5 76.1 48.0 64.4 69.4 50.4 65.3 50.3 24.7 60.4 64.7 138.5 72.0 76.0 21.6 84.2 118.0 62.7 43.3 105.8 94.4 61.1 59.5 42.8 30.2 96.3 48.0 20.8 39.6 51.9 56.0 49.9 34.1 76.8 112.5 89.0 22.6 152.1 81.8 75.8 57.6 178.1 159.3 165.8 71.8 163.9 68.0 68.5 73.2 71.2 163.1 78.9 57.9 63.7 57.8 86.5 169.6 101.3 107.5 140.1 45.5 50.0 47.8 61.3 54.9 48.8 50.5 45.7 52.3 43.9 49.1 47.2 44.4 35.3 33.8 5.5 49.2 80.9 67.5 103.9 37.5 34.9 48.4 57.9 55.1 50.1 55.0 51.5 29.2 99.8 48.2 145.0 207.4 93.4 132.0 42.2 39.4 44.6 62.3 41.4 5.6 90.5 98.7 48.2 47.9 39.8 93.8 43.6 43.2 35.4 131.0 18.5 6.4 107.0 79.3 98.0 77.0 284.2 53.4 75.6 67.6 3.7 116.4 50.8 64.9 3.0 5.0 73.5 133.8 58.6 49.7 35.6 222.4 253.1 50.7 49.3 52.6 47.4 68.2 15.9 18.3 50.3 77.4 110.8 55.2 103.0 112.7 64.2 IDNK "bA522I20.2, C9orf103, hGntK" ENSG00000148057 "IDNK gluconokinase" Q5T6J7 9 83623049-83644130 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 70.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 80.3;Proximal enterocytes: 84.2;Proximal tubular cells: 224.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020378, HPA058429" Approved Approved Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA020378: AB_1845794, HPA058429: AB_2683716" "unprognostic (1.49e-3)" "unprognostic (7.94e-2)" "unprognostic (3.30e-1)" "prognostic favorable (1.10e-6)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (5.41e-3)" "unprognostic (1.81e-2)" "unprognostic (6.08e-2)" "unprognostic (1.57e-1)" "unprognostic (2.61e-2)" "unprognostic (3.00e-1)" "unprognostic (5.86e-3)" "unprognostic (7.32e-2)" "unprognostic (1.07e-1)" "unprognostic (2.55e-1)" "unprognostic (3.11e-2)" 8.9 12.0 18.8 6.1 24.5 5.8 8.7 20.6 26.8 4.3 22.7 9.5 26.3 5.3 13.3 8.3 12.9 6.4 5.8 19.1 22.6 50.9 70.5 7.3 11.0 20.3 20.8 5.5 13.8 14.8 9.0 3.0 20.6 8.4 9.2 10.9 8.8 9.5 2.3 7.1 26.9 4.4 20.5 7.9 8.9 3.7 20.8 38.9 13.2 2.6 9.5 5.2 3.9 21.1 4.3 10.4 1.7 1.8 4.6 6.9 7.8 3.4 8.6 3.5 2.8 2.9 5.3 5.8 5.2 5.8 3.5 8.4 1.3 2.0 3.6 11.9 1.6 2.1 4.6 12.7 19.4 1.5 2.8 4.3 3.3 7.2 7.2 6.2 7.9 16.0 1.9 7.1 4.8 26.8 3.7 1.4 1.6 18.1 6.0 4.6 4.2 3.3 9.6 5.5 6.9 8.6 7.5 6.5 7.6 2.5 6.0 8.1 7.4 1.6 1.3 14.3 6.1 9.0 10.4 1.0 7.3 2.4 2.8 100.7 13.0 19.1 30.5 24.1 25.4 39.3 26.0 24.7 18.1 26.7 20.2 27.2 2.8 33.1 47.6 20.9 52.2 24.8 18.8 24.5 20.6 26.8 19.1 22.6 20.3 20.8 20.6 20.5 20.8 21.1 6.2 12.8 8.7 14.7 9.3 6.8 3.2 7.3 4.0 8.9 10.0 8.4 9.9 10.0 8.8 5.5 0.0 8.0 11.3 8.4 80.3 11.3 0.4 34.6 2.0 5.6 7.3 2.5 4.7 16.1 4.6 8.0 4.6 7.0 20.8 10.2 3.3 44.3 11.1 10.1 5.6 12.8 12.2 11.6 7.5 2.0 4.4 8.2 12.4 11.2 19.8 38.0 24.7 8.0 11.4 5.4 21.7 4.1 12.1 4.6 84.2 224.4 28.3 3.5 0.0 8.8 5.9 1.4 1.5 5.4 5.8 3.0 13.7 9.9 11.2 4.2 IDS "ID2S, SIDS" ENSG00000010404 "Iduronate 2-sulfatase" P22304 X 149476988-149521096 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 323.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 7 "amygdala: 194.3;basal ganglia: 212.9;cerebral cortex: 323.4;hippocampal formation: 320.5;white matter: 109.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078003 Approved "Intracellular and membrane" NA NA 17000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 24: Non-specific - Transcription regulation" "HPA078003: " "unprognostic (9.88e-2)" "unprognostic (1.10e-2)" "unprognostic (6.59e-2)" "unprognostic (1.45e-3)" "unprognostic (2.83e-2)" "unprognostic (4.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-1)" "unprognostic (9.76e-3)" "unprognostic (3.61e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" 32.7 43.3 194.3 29.5 212.9 47.6 27.9 0.0 323.4 37.5 0.0 35.7 21.1 35.1 43.5 26.1 35.7 26.3 42.2 320.5 25.7 22.7 15.8 40.5 31.0 9.7 9.4 45.4 23.3 57.0 67.8 16.3 3.1 29.4 20.8 48.6 24.7 41.0 25.1 37.1 27.9 30.5 0.2 34.1 23.0 6.1 32.3 17.2 27.2 38.9 36.0 32.8 31.5 109.4 46.4 50.7 19.6 12.7 22.1 40.9 9.2 26.6 67.8 23.3 43.9 10.2 32.7 110.0 69.6 38.3 49.1 22.6 21.3 40.5 30.1 40.8 17.7 11.5 14.7 5.7 17.8 18.8 101.3 21.4 19.6 50.9 33.1 95.5 37.8 20.2 5.7 76.6 34.7 57.9 19.6 9.3 17.5 28.8 34.3 12.4 19.4 20.7 27.8 10.5 28.9 67.6 9.8 22.1 32.0 33.2 6.9 7.9 44.3 29.9 31.3 50.1 70.8 54.5 47.3 79.3 138.0 44.3 22.1 117.5 56.9 171.7 70.9 63.0 53.2 35.2 43.1 54.0 48.7 27.0 28.4 42.9 261.1 37.2 73.9 36.8 74.0 63.0 194.3 212.9 0.0 323.4 320.5 25.7 9.7 9.4 3.1 0.2 32.3 109.4 53.7 99.3 64.4 55.8 150.9 33.1 60.6 44.0 20.5 178.3 43.2 43.8 44.1 27.1 58.9 82.8 45.9 34.2 158.5 66.9 21.5 50.2 1.3 59.8 36.8 44.7 168.4 19.6 232.3 74.0 25.7 78.3 31.1 49.5 226.2 25.5 60.3 33.0 44.0 222.1 243.7 29.0 73.2 94.8 109.8 3.7 72.7 98.4 51.6 63.7 120.9 55.0 146.2 39.2 95.8 85.0 50.3 89.5 98.8 71.3 74.6 22.3 112.4 59.5 59.2 68.1 65.2 3.5 6.6 22.2 43.8 143.0 183.9 16.4 17.1 96.9 IDUA "MPS1, MPSI" ENSG00000127415 Alpha-L-iduronidase P35475 4 986997-1004564 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025901, HPA046979, HPA054254" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 170000 "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB025901: , HPA046979: AB_2679888, HPA054254: AB_2682429" "unprognostic (3.62e-2)" "unprognostic (9.08e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (7.23e-2)" "unprognostic (1.45e-1)" "unprognostic (2.31e-2)" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.43e-2)" "unprognostic (1.89e-3)" "unprognostic (2.64e-2)" "unprognostic (4.61e-3)" "prognostic unfavorable (7.87e-5)" "unprognostic (2.24e-1)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "prognostic favorable (8.04e-5)" 13.5 17.6 3.4 2.2 3.4 2.9 16.1 9.2 7.5 17.5 2.9 10.3 3.6 15.4 2.4 9.9 16.3 3.7 11.6 3.8 1.5 15.9 13.6 13.9 3.5 3.2 2.1 17.0 21.0 2.8 17.2 1.7 2.4 18.5 1.8 1.8 16.6 4.5 3.7 8.9 14.3 2.0 1.0 18.9 17.1 5.6 2.9 3.4 17.0 0.7 1.3 12.0 13.9 2.6 1.8 0.4 0.0 1.1 12.7 3.6 5.3 10.7 8.5 1.2 1.7 0.6 6.4 0.8 10.7 5.0 1.0 0.5 0.1 0.3 0.4 6.1 0.6 1.0 0.8 0.1 5.8 0.8 4.6 9.3 3.1 0.6 0.0 3.4 1.0 0.7 0.6 0.0 1.6 0.0 2.2 2.5 0.8 11.9 5.5 2.7 0.0 1.1 3.5 0.9 0.1 3.3 0.3 0.0 5.7 1.3 1.2 2.3 9.3 9.0 1.6 2.6 1.2 29.0 1.4 0.4 7.8 3.3 1.8 0.0 1.5 0.0 1.4 1.2 1.8 0.1 1.1 0.9 1.8 0.2 1.3 0.7 0.0 1.5 1.7 1.1 0.6 0.5 3.4 3.4 9.2 7.5 3.8 1.5 3.2 2.1 2.4 1.0 2.9 2.6 8.7 6.4 5.0 4.9 5.2 3.6 11.5 1.1 8.6 2.0 8.5 9.1 2.6 1.5 1.5 7.3 4.2 0.4 4.3 5.0 0.0 1.6 0.9 4.1 9.0 4.9 10.7 1.3 4.4 2.4 1.7 13.4 16.8 6.0 2.5 8.2 6.1 2.6 6.5 0.0 2.9 4.2 0.0 5.0 3.6 0.9 19.6 7.3 5.4 1.0 1.6 1.1 4.1 5.5 3.3 1.4 6.9 10.5 15.7 7.7 6.9 1.4 1.4 2.1 0.0 5.5 4.4 3.7 1.6 4.7 1.8 0.4 5.6 4.7 4.3 7.9 IER3IP1 ENSG00000134049 "Immediate early response 3 interacting protein 1" Q9Y5U9 18 47152834-47176364 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Diabetes mellitus, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 357.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA010027 Supported Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "HPA010027: AB_1079098" "unprognostic (6.13e-2)" "unprognostic (2.96e-2)" "unprognostic (3.82e-2)" "unprognostic (1.45e-2)" "unprognostic (1.11e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (6.47e-6)" "unprognostic (9.86e-2)" "unprognostic (5.13e-2)" "prognostic favorable (8.59e-4)" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (1.53e-3)" "unprognostic (8.55e-2)" "unprognostic (2.71e-2)" "unprognostic (8.75e-2)" "unprognostic (1.27e-3)" 13.7 17.2 8.1 11.8 8.2 14.5 14.2 11.1 10.0 10.5 11.2 14.1 16.9 11.2 10.9 12.0 9.0 10.2 17.0 8.2 9.1 31.4 19.5 12.3 11.4 8.8 8.9 11.6 13.7 19.2 15.5 10.9 9.0 13.9 13.0 14.1 15.0 7.9 31.1 13.8 15.7 9.5 8.0 11.1 15.9 9.3 8.9 11.1 15.9 21.7 10.6 13.9 11.0 8.9 27.1 15.3 22.9 20.5 30.5 33.8 15.9 62.7 30.5 30.6 32.2 12.5 22.7 26.5 19.3 28.1 25.0 32.3 21.8 22.1 33.2 43.5 19.5 23.3 23.0 38.2 32.5 70.5 33.2 26.8 27.7 27.6 20.6 28.9 26.7 23.7 19.4 39.7 33.0 15.0 25.1 33.7 11.6 11.5 18.4 24.7 35.9 37.9 31.2 26.0 26.4 29.4 21.5 18.1 38.8 16.4 18.0 40.1 38.7 45.2 23.3 22.0 34.7 56.9 66.4 27.9 35.3 44.4 37.2 15.9 17.2 16.1 25.0 16.6 22.2 18.9 21.1 21.5 16.6 20.9 19.6 20.8 1.9 17.3 17.5 34.5 23.6 19.3 8.1 8.2 11.1 10.0 8.2 9.1 8.8 8.9 9.0 8.0 8.9 8.9 80.8 86.6 51.8 7.8 58.9 0.0 64.6 0.0 73.4 48.0 96.0 51.4 63.1 97.2 19.2 51.5 8.4 104.9 61.3 35.6 140.8 124.3 18.4 49.5 47.7 70.8 37.6 51.3 15.7 138.9 126.3 76.2 57.6 55.6 13.9 40.0 83.6 138.8 108.9 40.4 17.4 69.1 0.0 63.6 0.0 13.3 84.8 54.8 0.0 12.2 79.4 69.6 86.5 16.1 19.1 139.3 50.1 48.5 158.8 117.3 125.0 357.0 26.2 48.0 52.6 40.4 61.6 163.3 158.9 88.1 0.0 177.2 54.4 36.7 62.2 109.4 IFI27L1 FAM14B ENSG00000165948 "Interferon alpha inducible protein 27 like 1" Q96BM0 14 94081301-94103846 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 97.6" "Cell type enhanced" "Detected in all" "Early spermatids: 328.4;Late spermatids: 160.8;Theca cells: 125.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 16.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 202.4" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (7.89e-3)" "unprognostic (1.47e-1)" "unprognostic (6.31e-2)" "unprognostic (8.54e-3)" "unprognostic (2.53e-1)" "unprognostic (4.81e-2)" "unprognostic (1.84e-2)" "unprognostic (2.63e-1)" "unprognostic (3.68e-1)" "unprognostic (7.63e-3)" "unprognostic (2.50e-1)" "unprognostic (2.00e-1)" "unprognostic (3.90e-2)" "unprognostic (3.50e-2)" "unprognostic (1.71e-1)" "unprognostic (5.93e-3)" "unprognostic (2.92e-1)" 15.7 51.0 28.6 6.6 28.3 20.0 13.1 28.6 31.6 11.3 33.4 14.0 11.9 10.2 23.0 11.5 11.3 9.5 17.1 28.4 30.5 14.3 10.6 13.9 6.8 29.6 30.0 28.5 9.5 12.8 13.3 4.5 30.2 7.5 13.8 17.2 11.8 7.2 20.1 13.1 12.6 9.6 28.6 12.6 16.5 97.6 30.2 12.9 9.2 14.4 10.2 6.6 11.0 29.8 16.8 16.3 23.9 23.7 29.6 27.2 10.9 20.2 21.8 19.5 47.0 5.5 38.1 16.1 31.5 16.5 20.4 17.7 3.5 12.0 13.9 43.0 20.0 14.1 34.4 10.9 14.4 16.9 15.6 25.3 14.0 22.0 15.6 33.0 15.7 70.8 28.8 202.4 32.3 14.6 18.5 16.0 8.1 32.3 13.9 33.6 21.1 25.4 23.4 3.1 20.7 11.3 35.1 15.8 29.4 16.0 22.4 27.3 17.4 9.6 7.4 19.0 15.2 43.6 46.3 24.4 31.4 18.4 12.3 16.2 1.6 2.3 2.3 1.8 2.1 2.4 4.0 3.2 1.5 2.8 2.7 3.3 0.8 3.9 1.6 4.6 5.4 1.6 28.6 28.3 28.6 31.6 28.4 30.5 29.6 30.0 30.2 28.6 30.2 29.8 28.7 28.9 13.7 15.7 15.3 17.1 22.9 34.4 18.2 17.9 20.7 21.5 18.8 14.3 23.0 20.2 10.4 19.3 11.1 53.5 27.4 27.4 328.4 33.7 14.4 20.1 15.5 12.8 4.6 26.7 14.0 26.5 23.4 18.8 5.7 72.2 30.4 14.3 35.7 13.5 5.5 59.4 44.7 10.0 12.2 160.8 42.6 11.8 26.6 3.7 5.5 44.6 14.4 6.0 7.5 26.2 43.5 57.2 44.7 13.6 88.1 33.5 20.0 30.1 13.1 11.7 17.6 30.0 39.0 21.6 14.2 7.1 14.0 125.3 31.6 23.8 IFI27L2 "FAM14A, TLH29" ENSG00000119632 "Interferon alpha inducible protein 27 like 2" Q9H2X8 14 94127779-94130253 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 446.8" HPA049588 Approved Nucleoli,Cytosol "Intracellular and membrane" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Nucleoli "HPA049588: " "unprognostic (9.70e-3)" "unprognostic (2.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.76e-1)" "unprognostic (2.45e-1)" "unprognostic (2.80e-2)" "unprognostic (7.46e-3)" "unprognostic (4.76e-2)" "unprognostic (4.69e-2)" "unprognostic (1.58e-2)" "unprognostic (4.79e-3)" "unprognostic (3.96e-2)" "unprognostic (8.13e-2)" "unprognostic (2.03e-1)" "unprognostic (3.88e-1)" "unprognostic (5.09e-2)" "unprognostic (3.52e-2)" 47.8 114.5 148.9 42.4 157.0 46.6 43.1 159.2 207.3 76.4 142.8 57.3 22.5 51.5 14.5 73.9 54.1 46.4 108.2 149.3 169.0 68.2 10.2 60.0 57.9 162.6 152.7 78.8 27.8 55.0 83.3 10.7 162.3 35.8 20.4 51.6 26.7 21.6 8.8 52.5 52.8 25.6 160.9 72.2 35.5 31.1 160.1 46.9 35.1 9.9 50.5 41.6 72.1 171.9 61.5 39.3 10.8 90.8 70.1 166.5 7.6 118.1 129.9 92.3 99.6 12.1 28.0 29.0 128.3 134.2 59.1 81.6 8.8 150.5 36.8 185.4 3.0 44.0 41.0 4.6 98.5 53.2 116.7 163.1 55.8 50.5 39.0 162.6 49.1 108.5 3.8 446.8 107.5 128.3 32.3 33.9 16.4 41.9 49.2 1.9 40.2 42.2 137.8 25.2 24.1 28.7 3.8 0.0 78.4 22.9 146.4 87.6 65.9 61.5 35.0 79.5 30.1 171.8 164.4 10.4 201.7 124.1 39.2 167.4 238.3 48.0 153.4 167.9 99.4 214.2 140.6 168.4 184.2 201.3 104.2 134.9 37.6 44.3 121.5 153.5 203.5 217.4 148.9 157.0 159.2 207.3 149.3 169.0 162.6 152.7 162.3 160.9 160.1 171.9 86.5 38.5 50.9 10.1 71.8 92.8 73.1 218.3 111.0 27.2 47.9 103.6 162.8 50.1 55.8 178.4 20.9 2.3 79.3 58.2 178.1 159.2 8.2 78.1 113.7 70.1 99.6 20.6 1.6 29.1 2.7 133.0 43.8 11.6 90.7 64.8 121.1 4.2 190.8 23.5 3.6 193.8 57.0 163.7 107.6 31.1 183.0 119.1 236.5 0.0 134.7 181.0 137.0 5.5 13.9 68.1 150.2 115.5 104.4 23.7 125.6 113.3 61.8 113.3 124.9 70.4 87.7 8.3 22.1 105.2 66.9 2.9 92.2 92.7 82.8 55.9 IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 572.7;lymphoid tissue: 708.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 155.9;Kupffer cells: 205.4;Langerhans cells: 139.3;Macrophages: 426.2;monocytes: 144.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9509.8;eosinophil: 3890.4;intermediate monocyte: 14243.6;myeloid DC: 5699.9;non-classical monocyte: 9865.9" "Group enriched" "Detected in all" 8 "dendritic cells: 5699.9;granulocytes: 3890.4;monocytes: 14243.6" "Cell line enhanced" "Detected in many" "Daudi: 655.7;RPMI-8226: 717.7;SK-BR-3: 457.4;U-266/84: 794.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 110000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA026650: AB_10602237" "unprognostic (4.66e-2)" "unprognostic (1.25e-4)" "unprognostic (2.35e-3)" "unprognostic (7.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-3)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (9.19e-3)" "unprognostic (3.04e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-11)" "unprognostic (3.50e-1)" "unprognostic (1.62e-2)" "unprognostic (3.39e-2)" "unprognostic (9.59e-3)" 132.4 121.0 18.4 708.3 20.8 283.8 58.6 20.3 104.5 40.8 48.7 129.0 197.3 22.2 26.9 38.7 57.3 109.6 31.2 18.0 23.3 80.3 148.2 572.7 370.7 32.0 24.9 14.8 61.3 75.0 27.9 128.8 40.5 31.6 148.0 2.6 66.3 22.0 12.6 55.0 153.6 165.0 26.8 385.3 112.2 16.0 69.4 91.9 54.2 9.0 221.0 215.7 19.6 49.8 115.5 59.2 0.4 37.9 11.2 19.9 102.6 11.8 17.2 34.6 91.8 132.3 193.1 655.7 96.6 39.7 175.2 85.1 69.9 30.1 3.7 182.5 55.2 8.1 98.1 188.9 111.8 20.1 46.9 70.4 60.4 59.8 19.7 4.4 2.0 23.8 96.8 394.8 16.6 217.3 9.9 2.5 21.2 380.6 68.7 65.8 4.5 717.7 101.1 3.7 5.3 8.0 200.5 457.4 11.3 7.4 31.6 8.8 4.2 55.2 34.2 120.7 12.0 14.6 794.7 368.5 154.1 133.5 8.5 106.9 9509.8 3890.4 40.8 14243.6 38.8 952.6 28.5 31.1 5699.9 708.1 19.7 24.3 2102.8 70.2 9865.9 173.2 41.5 11082.7 18.4 20.8 20.3 104.5 18.0 23.3 32.0 24.9 40.5 26.8 69.4 49.8 6.4 9.6 38.8 0.0 54.2 3.6 2.5 2.1 2.2 0.4 8.6 13.2 1.1 4.3 18.3 12.9 0.0 5.6 4.0 8.3 1.9 1.8 0.3 2.5 1.7 8.4 0.0 4.6 0.1 1.1 14.8 8.1 6.6 4.1 13.9 0.2 3.6 1.3 155.9 0.0 0.1 14.9 2.0 205.4 139.3 0.2 0.3 426.2 5.4 1.0 144.1 0.7 5.2 0.0 0.1 1.2 3.4 0.0 47.7 4.6 5.9 5.4 8.9 0.7 0.0 2.6 1.8 0.2 0.7 3.7 3.3 12.0 9.6 1.5 9.6 1.2 IFNA1 "IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA@, IFNA13" ENSG00000197919 "Interferon alpha 1" P01562 9 21440439-21441316 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.2;hTERT-RPE1: 2.2" HPA047557 Uncertain "Secreted to blood" NA NA 10000 "Cluster 20: HeLa - Mitochondria" "HPA047557: AB_2680087" "unprognostic (3.14e-1)" "unprognostic (1.55e-1)" "unprognostic (9.75e-2)" "unprognostic (5.88e-2)" 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.0 0.1 0.1 0.4 0.1 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA10 IFN-alphaC ENSG00000186803 "Interferon alpha 10" P01566 9 21206181-21207143 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA13 ENSG00000233816 "Interferon alpha 13" P01562 9 21367424-21368962 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.4" "Cell type enriched" "Detected in single" 17 "Granulosa cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Granulosa cells - Unknown function" "HPA047557: AB_2680087" 0.0 0.0 0.8 0.0 1.4 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.4 0.2 1.0 0.6 0.5 0.6 0.7 0.5 0.1 1.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA14 "IFN-alphaH, LEIF2H" ENSG00000228083 "Interferon alpha 14" P01570 9 21239002-21240005 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "Cluster 41: Macrophages - Immune response" "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA16 IFN-alphaO ENSG00000147885 "Interferon alpha 16" P05015 9 21216373-21217311 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA17 "IFN-alphaI, LEIF2C1" ENSG00000234829 "Interferon alpha 17" P01571 9 21227243-21228222 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA2 "IFN-alphaA, IFNA" ENSG00000188379 "Interferon alpha 2" P01563 9 21384255-21385398 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "brain: 1.6" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 2.5;Granulosa cells: 1.7;Oligodendrocytes: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA 253000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA047557: AB_2680087" 0.0 0.0 0.8 0.0 1.6 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.6 0.2 0.8 0.5 0.8 0.7 0.7 0.6 0.2 0.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA21 IFN-alphaI ENSG00000137080 "Interferon alpha 21" P01568 9 21165637-21166660 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA4 "IFN-alpha4a, MGC142200" ENSG00000236637 "Interferon alpha 4" P05014 9 21186694-21187671 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA5 IFN-alphaG ENSG00000147873 "Interferon alpha 5" P01569 9 21304326-21305312 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.1 0.2 0.1 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA6 IFN-alphaK ENSG00000120235 "Interferon alpha 6" P05013 9 21349835-21351378 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "Cluster 57: B-cells - Immune response" "HPA047557: AB_2680087" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.3 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA7 "IFN-alphaJ, IFNA-J" ENSG00000214042 "Interferon alpha 7" P01567 9 21201469-21202205 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA8 IFN-alphaB ENSG00000120242 "Interferon alpha 8" P32881 9 21409117-21410185 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNAR1 "IFNAR, IFRC" ENSG00000142166 "Interferon alpha and beta receptor subunit 1" P17181 21 33324429-33359864 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029226 Approved NA NA 170000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA029226: AB_2672954" "unprognostic (2.42e-3)" "unprognostic (2.95e-1)" "unprognostic (3.01e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (3.02e-1)" "unprognostic (4.69e-2)" "unprognostic (1.28e-1)" "unprognostic (2.31e-2)" "unprognostic (2.38e-1)" "unprognostic (9.38e-3)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (8.45e-2)" "unprognostic (3.06e-2)" 40.8 22.3 14.3 36.4 14.6 30.8 32.3 15.7 15.2 26.3 9.6 28.9 26.7 22.4 23.2 25.2 23.8 30.2 21.2 15.0 16.2 32.0 76.6 29.7 28.8 17.4 15.6 23.5 29.2 40.5 7.7 49.5 16.9 27.2 30.5 23.6 30.2 24.1 32.7 20.5 27.4 24.0 15.7 33.5 31.6 20.9 17.5 33.1 41.2 24.8 29.7 39.8 9.0 18.6 47.3 24.4 27.4 24.2 55.8 80.8 23.7 44.6 74.2 32.9 36.1 31.7 57.2 42.4 35.4 49.4 36.3 28.4 23.3 37.0 43.8 33.8 26.0 62.8 29.0 20.2 33.9 50.8 43.3 58.2 38.4 43.6 37.7 39.4 63.1 40.3 67.6 198.2 56.5 22.8 38.7 22.2 24.9 46.6 25.6 29.5 75.0 62.4 33.7 44.0 22.5 24.1 50.5 42.4 39.3 20.8 58.2 36.8 61.3 39.3 24.7 58.2 28.2 102.3 132.7 43.2 66.3 64.4 50.5 77.3 45.4 27.7 23.6 64.0 23.1 56.2 31.5 28.6 37.4 57.0 37.0 29.0 166.7 28.0 80.3 54.3 41.2 35.2 14.3 14.6 15.7 15.2 15.0 16.2 17.4 15.6 16.9 15.7 17.5 18.6 101.2 109.0 45.8 17.6 69.3 45.8 57.0 72.3 18.8 51.9 42.5 29.7 33.5 34.3 78.8 44.1 29.2 28.1 43.8 25.3 21.5 73.0 17.7 37.9 58.4 75.5 26.9 27.1 26.3 90.5 92.4 61.1 35.7 44.5 39.2 30.3 53.9 81.3 69.2 58.9 29.4 28.9 46.8 82.1 47.5 10.7 32.6 77.6 37.4 30.9 86.8 34.3 42.2 34.2 27.2 64.7 25.5 30.9 137.3 63.9 37.6 28.7 59.6 30.0 19.7 54.9 44.9 38.5 17.5 21.5 44.9 20.1 38.3 25.1 27.5 72.2 IFNAR2 IFNABR ENSG00000159110 "Interferon alpha and beta receptor subunit 2" P48551 21 33229901-33265675 "Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 188.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 211.2;U-266/70: 261.6;U-266/84: 145.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.00e-2)" "unprognostic (7.83e-3)" "unprognostic (4.98e-2)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-3)" "unprognostic (8.05e-2)" "unprognostic (4.17e-2)" "unprognostic (2.11e-2)" "unprognostic (7.65e-2)" "unprognostic (4.42e-1)" "prognostic unfavorable (7.54e-7)" "unprognostic (9.70e-3)" "unprognostic (2.39e-1)" "unprognostic (5.12e-3)" "unprognostic (1.85e-2)" 21.3 9.0 13.2 33.2 13.6 29.1 16.4 11.5 14.8 12.7 9.7 16.7 17.4 11.7 8.2 8.0 11.7 21.0 13.4 11.0 14.3 14.3 28.7 22.6 33.5 16.7 14.0 11.8 10.0 12.5 10.1 22.9 15.1 10.1 17.4 8.3 13.7 11.3 9.0 7.0 16.2 18.3 13.6 41.0 14.8 5.3 15.8 33.9 10.7 10.8 36.4 38.2 9.0 14.0 17.0 18.4 9.9 23.7 11.9 27.3 16.2 18.1 45.1 14.2 15.7 24.4 20.8 28.3 12.8 25.4 22.8 10.9 15.2 9.2 15.0 18.3 19.9 100.9 19.1 22.2 17.5 17.5 38.0 20.7 8.7 16.8 18.5 24.8 46.0 41.5 30.2 211.2 13.7 9.1 44.0 19.6 18.3 24.2 11.7 14.9 53.4 50.7 30.8 31.9 26.6 14.2 29.5 28.2 23.9 10.4 4.4 30.5 32.2 15.3 9.3 12.5 10.1 261.6 145.3 64.3 20.5 60.3 37.5 44.5 38.5 63.8 31.2 65.0 32.2 25.7 37.9 29.3 36.6 17.1 27.5 30.8 101.2 35.2 73.4 101.0 65.8 41.3 13.2 13.6 11.5 14.8 11.0 14.3 16.7 14.0 15.1 13.6 15.8 14.0 35.6 60.9 16.1 19.6 49.4 6.8 43.8 41.7 2.8 6.6 11.4 12.4 2.2 20.0 23.6 11.0 6.2 28.9 64.4 6.0 3.9 67.5 3.0 6.7 10.0 39.0 3.0 27.6 44.4 62.7 72.1 15.4 4.6 8.5 31.7 11.8 44.6 19.6 44.9 20.2 42.3 4.4 4.1 73.5 17.1 3.3 7.5 58.5 19.6 74.9 47.9 6.4 89.6 51.3 29.4 73.8 5.9 9.1 188.8 89.5 17.3 10.2 35.2 5.6 0.0 16.8 12.5 4.2 19.9 4.3 5.7 23.5 43.9 2.5 4.9 83.2 IFNB1 "IFB, IFF, IFNB" ENSG00000171855 "Interferon beta 1" P01574 9 21077104-21077942 "Cancer-related genes, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "Hofbauer cells: 2.2;Macrophages: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BJ hTERT+ SV40 Large T+ RasG12V: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA073843 Supported "Secreted to blood" NA NA 3750 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" "HPA073843: " "unprognostic (2.38e-1)" "unprognostic (2.60e-4)" 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IFNE IFNE1 ENSG00000184995 "Interferon epsilon" Q86WN2 9 21480839-21482313 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 1.5" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 4.4;Basal respiratory cells: 3.7;Club cells: 1.2;Glandular and luminal cells: 1.5;Prostatic glandular cells: 2.9;Urothelial cells: 4.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 3.2;HeLa: 9.6;hTERT-RPE1: 9.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (1.52e-3)" "unprognostic (8.36e-2)" "unprognostic (5.44e-2)" "unprognostic (1.56e-5)" "unprognostic (2.70e-1)" "unprognostic (2.25e-1)" "unprognostic (5.14e-3)" "unprognostic (6.32e-1)" "unprognostic (2.68e-2)" "unprognostic (1.14e-2)" "unprognostic (1.43e-2)" "unprognostic (9.63e-3)" "unprognostic (1.04e-1)" "unprognostic (3.27e-2)" "unprognostic (6.58e-3)" "unprognostic (3.34e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.8 0.6 0.0 0.0 0.3 0.1 0.9 1.5 0.4 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.3 0.6 0.0 0.7 0.1 0.2 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.0 0.5 0.0 0.3 0.0 0.2 1.1 0.9 0.3 1.1 1.9 0.0 0.0 0.9 0.9 0.1 3.2 0.2 0.1 0.2 0.0 2.1 0.0 0.6 0.6 0.3 1.1 0.0 2.0 0.3 0.0 0.0 0.0 9.6 0.0 0.5 0.0 0.0 0.8 0.4 1.2 1.8 9.9 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.8 0.0 0.1 0.3 0.2 0.3 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.4 3.7 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.9 0.5 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.7 IFNG ENSG00000111537 "Interferon gamma" P01579 12 68154768-68159740 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense, Growth regulation" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.5;lymphoid tissue: 7.4" "Group enriched" "Detected in many" 12 "dendritic cells: 283.2;T-cells: 200.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "gdT-cell: 5.5;memory CD4 T-cell: 2.4;memory CD8 T-cell: 6.6;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB010344 Approved "Secreted to blood" NA NA 1470 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 7: Non-specific - Mitochondria" "CAB010344: AB_2123447" "unprognostic (2.16e-4)" "unprognostic (1.93e-3)" "unprognostic (9.21e-2)" "unprognostic (1.04e-4)" "unprognostic (5.14e-1)" "unprognostic (3.96e-3)" "unprognostic (1.33e-1)" "unprognostic (3.17e-4)" "unprognostic (7.79e-2)" "unprognostic (7.97e-3)" "unprognostic (1.63e-2)" "unprognostic (5.36e-2)" "unprognostic (7.62e-9)" "unprognostic (3.54e-2)" "unprognostic (5.36e-1)" "unprognostic (6.32e-2)" "unprognostic (7.38e-3)" 0.7 0.7 0.1 3.5 0.2 11.5 0.3 0.0 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.0 0.0 0.3 1.5 1.8 7.4 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.9 0.2 0.0 0.0 0.3 0.2 0.0 1.3 0.4 0.1 0.1 0.5 0.3 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 2.4 6.6 0.0 0.4 0.5 3.7 0.1 0.9 0.0 0.0 0.1 0.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.7 0.0 0.0 0.0 3.1 3.2 1.3 0.0 0.0 0.0 4.8 5.5 0.2 1.5 0.0 0.0 0.0 0.0 283.2 0.1 0.0 0.0 0.2 1.0 1.1 1.3 0.0 0.4 0.0 0.0 0.0 1.5 6.1 1.1 0.0 0.0 1.4 1.2 0.1 0.0 0.0 0.5 0.0 4.4 5.5 0.0 0.0 10.4 7.2 0.0 0.0 0.0 19.6 0.0 0.1 0.0 1.1 0.0 10.9 0.2 0.0 0.3 0.0 0.0 0.0 1.0 2.9 0.0 0.0 0.8 4.0 0.0 200.1 0.0 0.2 0.2 IFNGR1 "CD119, IFNGR" ENSG00000027697 "Interferon gamma receptor 1" P15260 6 137197485-137219449 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 867.1;Club cells: 405.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025889, HPA029213, HPA063871" Approved Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB025889: , HPA029213: AB_10601023, HPA063871: AB_2685138" "unprognostic (1.73e-1)" "unprognostic (8.86e-2)" "unprognostic (9.85e-3)" "unprognostic (1.71e-1)" "unprognostic (6.55e-2)" "unprognostic (1.25e-1)" "unprognostic (4.05e-1)" "unprognostic (6.97e-2)" "unprognostic (9.86e-2)" "unprognostic (1.57e-2)" "unprognostic (4.09e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.58e-1)" "unprognostic (2.87e-2)" "unprognostic (1.81e-2)" "unprognostic (5.38e-3)" 155.5 59.3 54.6 131.5 57.8 146.2 121.4 64.5 72.1 74.1 56.8 74.7 97.9 58.1 67.4 65.0 55.7 88.4 103.7 53.1 59.9 44.4 104.0 153.8 140.2 71.9 60.3 43.3 44.5 47.4 26.3 86.1 75.9 53.2 74.4 40.4 57.7 57.4 58.3 66.2 101.2 75.9 69.2 165.9 51.3 27.9 59.9 69.2 58.3 75.5 135.2 112.6 58.0 85.0 23.2 23.4 25.1 33.4 166.8 86.7 23.0 67.0 90.0 38.0 53.3 148.7 39.8 24.5 99.2 36.1 55.1 130.0 24.1 62.6 51.5 49.4 37.4 36.1 23.3 192.9 97.3 112.9 46.6 195.9 232.6 33.3 51.4 36.1 48.7 29.1 32.0 34.9 29.2 27.7 17.7 47.0 22.0 191.9 18.6 51.3 28.4 32.1 65.5 104.4 27.4 39.5 77.3 41.9 57.5 47.8 15.5 68.7 71.1 36.2 27.7 48.5 31.8 25.3 25.5 23.8 19.4 69.2 36.5 158.6 518.4 356.3 106.9 502.6 224.7 91.3 60.0 90.0 309.4 98.3 39.2 43.1 736.0 48.4 375.6 85.1 48.0 519.3 54.6 57.8 64.5 72.1 53.1 59.9 71.9 60.3 75.9 69.2 59.9 85.0 298.7 80.1 59.9 21.5 76.4 127.6 177.6 867.1 84.2 15.4 49.8 37.3 49.6 37.1 405.7 27.6 12.5 78.5 240.8 111.0 7.9 74.2 11.6 91.4 52.7 110.7 13.1 25.7 21.4 101.4 67.1 94.7 33.6 112.8 63.3 10.3 62.8 56.5 149.8 10.1 24.2 25.5 270.6 326.2 220.0 6.1 44.1 261.7 49.8 147.1 138.4 23.5 52.5 25.1 44.9 76.0 57.6 49.2 74.5 129.6 82.0 17.2 150.6 28.1 13.1 45.7 75.7 14.6 22.4 47.3 113.2 209.9 121.5 48.3 33.9 140.2 IFNK ENSG00000147896 "Interferon kappa" Q9P0W0 9 27524290-27526498 "Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "brain: 4.1;choroid plexus: 2.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 0.5;head and neck cancer: 0.6;urothelial cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 44: Endometrium - Transcription" "unprognostic (5.58e-3)" "unprognostic (4.64e-3)" "unprognostic (1.06e-1)" 0.0 0.0 1.0 0.0 3.4 0.0 0.0 1.5 1.7 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.5 0.0 0.0 0.0 0.0 3.2 2.4 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.4 1.5 1.7 0.8 1.5 3.2 2.4 2.6 2.0 3.2 4.1 0.1 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNL1 "IL-29, IL29" ENSG00000182393 "Interferon lambda 1" Q8IU54 19 39296407-39298673 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "dendritic cells: 3.0;Langerhans cells: 6.4;NK-cells: 14.4;T-cells: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "gdT-cell: 2.7;MAIT T-cell: 2.8;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.7;myeloid DC: 2.3;naive CD8 T-cell: 1.4;NK-cell: 4.6" "Group enriched" "Detected in many" 33 "dendritic cells: 2.3;NK-cells: 4.6;T-cells: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 97000 "Cluster 48: NK-cells - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.08e-2)" "unprognostic (8.74e-2)" "unprognostic (2.46e-4)" "unprognostic (5.76e-2)" "unprognostic (6.91e-3)" "unprognostic (5.73e-3)" "unprognostic (3.94e-2)" "unprognostic (4.80e-2)" "unprognostic (2.96e-5)" "unprognostic (7.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (1.58e-1)" 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 2.8 0.0 1.3 2.7 2.3 0.0 0.1 1.4 0.0 4.6 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.5 0.0 0.0 0.4 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.6 0.0 0.0 0.0 IFNL2 "IL-28A, IL28A" ENSG00000183709 "Interferon lambda 2" Q8IZJ0 19 39268396-39270188 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 15 "Breast myoepithelial cells: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 17 "HDLM-2: 10.9" CAB025489 Uncertain "Secreted to blood" NA NA "Cluster 44: HDLM-2 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" "CAB025489: " "unprognostic (1.37e-1)" "unprognostic (2.84e-1)" "unprognostic (1.05e-1)" "unprognostic (2.11e-2)" "unprognostic (1.08e-1)" "unprognostic (6.96e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNL3 "IL-28B, IL28B, IL28C" ENSG00000197110 "Interferon lambda 3" Q8IZI9 19 39243553-39245129 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 1700 "unprognostic (2.67e-1)" "unprognostic (9.19e-2)" "unprognostic (4.17e-1)" "unprognostic (6.86e-2)" "unprognostic (1.89e-2)" "unprognostic (1.66e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNLR1 "CRF2/12, IFNLR, IL-28R1, IL28RA" ENSG00000185436 "Interferon lambda receptor 1" Q8IU57 1 24154168-24187959 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 17.4;Proximal enterocytes: 18.2;Urothelial cells: 17.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "memory B-cell: 4.9;naive B-cell: 5.9;plasmacytoid DC: 11.3" "Group enriched" "Detected in many" 5 "B-cells: 5.9;dendritic cells: 11.3" "Cell line enhanced" "Detected in many" "U-266/70: 51.4;U-266/84: 19.4;U-698: 40.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017319 Uncertain Approved Cytosol "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA017319: AB_1851708" "prognostic favorable (5.12e-4)" "unprognostic (7.16e-2)" "unprognostic (8.61e-3)" "unprognostic (8.48e-2)" "unprognostic (8.09e-2)" "unprognostic (1.22e-2)" "unprognostic (7.28e-3)" "unprognostic (2.33e-1)" "unprognostic (5.10e-2)" "unprognostic (1.93e-1)" "unprognostic (5.51e-2)" "unprognostic (4.50e-1)" "unprognostic (3.66e-3)" "unprognostic (5.15e-2)" "unprognostic (1.69e-1)" "unprognostic (2.69e-1)" "unprognostic (1.10e-1)" 0.4 2.2 1.1 2.8 1.2 0.6 2.6 6.2 1.1 1.7 2.2 3.8 5.8 0.9 1.9 3.6 1.8 2.1 3.1 0.8 2.6 3.0 8.4 2.9 7.8 2.5 2.2 1.3 5.0 5.2 5.9 0.3 2.5 3.4 4.0 1.8 4.5 2.1 3.6 7.3 9.2 0.4 1.9 2.8 2.9 1.0 2.7 1.4 4.4 1.3 9.7 2.1 2.3 2.7 6.7 1.3 0.0 0.0 0.0 0.0 1.6 0.0 0.6 1.2 1.0 11.3 1.9 14.3 15.1 0.0 5.4 5.0 6.6 11.6 0.9 3.0 3.5 0.0 2.3 3.4 0.0 0.0 0.0 0.0 3.8 0.3 3.5 2.5 0.0 2.9 0.3 0.0 0.0 1.6 0.2 0.4 14.0 0.5 4.1 0.1 0.0 1.2 2.6 2.8 2.0 1.3 3.5 2.0 1.4 2.4 2.7 0.1 0.0 0.0 2.7 0.0 0.1 51.4 19.4 40.8 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.3 4.9 0.3 1.4 0.0 5.9 0.5 1.4 0.0 0.0 0.0 11.3 0.3 0.5 1.1 1.2 6.2 1.1 0.8 2.6 2.5 2.2 2.5 1.9 2.7 2.7 0.5 0.0 4.8 2.3 5.9 11.1 10.0 4.1 12.5 3.4 1.4 3.2 3.5 2.8 2.3 1.8 0.0 0.6 5.3 17.4 3.9 2.9 2.2 3.4 0.2 0.5 0.0 0.0 2.2 2.3 1.0 0.8 3.1 2.7 0.0 1.5 0.0 8.4 2.3 0.0 2.8 4.1 0.0 0.8 1.9 4.3 0.3 3.0 0.0 2.8 5.5 2.9 0.0 0.5 0.1 2.4 6.1 0.0 12.5 4.3 18.2 2.3 5.1 2.3 0.0 0.0 0.6 0.0 0.7 8.3 12.6 0.3 2.2 0.1 3.3 17.2 IFNW1 ENSG00000177047 "Interferon omega 1" P05000 9 21140214-21142145 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFRD1 "PC4, TIS7" ENSG00000006652 "Interferon related developmental regulator 1" O00458 7 112422887-112481017 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 64.2;neutrophil: 112.3" "Lineage enriched" "Detected in all" 13 "granulocytes: 112.3" "Low cell line specificity" "Detected in all" "HPA024122, HPA072413" Enhanced Approved "Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 17: WM-115 - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA024122: AB_1851452, HPA072413: " "unprognostic (2.29e-1)" "unprognostic (3.47e-1)" "unprognostic (1.10e-1)" "unprognostic (9.82e-3)" "unprognostic (1.36e-2)" "unprognostic (2.39e-1)" "unprognostic (5.73e-3)" "unprognostic (1.37e-1)" "unprognostic (2.48e-2)" "prognostic favorable (5.45e-4)" "unprognostic (6.41e-2)" "unprognostic (2.93e-3)" "unprognostic (1.50e-3)" "unprognostic (4.81e-2)" "unprognostic (1.98e-1)" "unprognostic (2.89e-1)" "unprognostic (4.70e-2)" 35.2 24.6 11.2 6.5 14.4 57.7 32.3 13.2 16.2 23.0 31.7 30.3 8.1 20.8 4.8 24.0 25.4 4.6 30.9 13.9 19.0 21.3 27.3 40.1 3.9 11.0 13.2 31.3 102.9 9.8 31.2 7.9 13.0 28.1 5.5 13.4 25.7 6.4 58.9 21.9 22.2 10.2 11.7 19.9 38.3 24.5 13.1 4.5 25.6 3.1 3.9 24.1 25.8 19.6 22.1 26.8 25.9 21.7 44.4 28.2 25.0 23.8 26.6 36.0 29.6 42.7 21.1 12.2 52.9 18.8 64.6 15.0 21.5 29.2 46.9 17.1 31.7 13.8 46.1 37.9 61.5 19.9 9.5 24.7 43.4 39.7 47.1 18.9 18.3 22.2 46.5 17.4 14.2 35.7 24.1 20.1 51.8 26.9 30.1 24.6 9.2 22.9 6.0 6.1 37.9 18.9 28.0 15.5 61.2 57.7 9.8 15.2 12.6 45.8 10.4 35.0 68.5 27.2 34.8 37.1 12.9 43.6 63.8 19.8 7.6 64.2 7.2 6.5 6.2 8.7 7.7 7.9 6.6 7.2 6.8 7.0 112.3 8.0 6.4 4.6 8.6 5.2 11.2 14.4 13.2 16.2 13.9 19.0 11.0 13.2 13.0 11.7 13.1 19.6 179.3 32.1 31.4 39.2 110.6 197.3 159.3 55.6 259.6 50.3 141.7 142.6 60.6 37.1 55.0 18.4 89.6 66.5 130.9 276.0 17.6 49.6 43.9 123.2 159.7 96.8 138.2 24.6 36.1 56.5 84.2 135.5 162.6 190.1 74.4 51.3 52.8 21.7 126.1 21.9 24.4 183.5 54.9 96.9 153.4 10.1 36.7 141.8 103.2 44.0 55.8 32.4 20.6 24.1 42.6 55.1 287.8 41.0 104.6 143.9 226.9 13.3 34.1 86.8 39.5 138.9 172.7 25.5 14.5 135.1 126.0 151.7 129.8 53.4 180.0 154.4 IGF1 "IGF, IGF-I, IGF1A, IGFI" ENSG00000017427 "Insulin like growth factor 1" P05019 12 102395874-102481744 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 86.7;cervix: 89.0" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 1279.3;Leydig cells: 1103.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.4" "Lineage enriched" "Detected in single" 24 "B-cells: 2.4" "Cell line enhanced" "Detected in some" "ASC diff: 37.9;HDLM-2: 49.6;K-562: 22.4;Karpas-707: 11.3;U-266/70: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048946 Approved "Secreted to blood" NA NA 103000000 330000000 "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "HPA048946: AB_2680566" "unprognostic (1.25e-1)" "unprognostic (2.86e-3)" "unprognostic (1.46e-1)" "prognostic favorable (1.04e-4)" "unprognostic (1.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.59e-3)" "unprognostic (2.26e-1)" "unprognostic (9.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.04e-2)" "unprognostic (2.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-3)" 86.7 5.1 1.2 27.1 1.8 0.9 38.7 0.3 2.3 89.0 1.3 6.9 5.4 46.9 10.6 6.6 13.0 21.5 15.1 2.2 1.0 3.1 83.5 11.6 6.5 2.5 1.1 9.0 3.9 1.4 1.2 24.2 2.0 38.5 6.7 5.4 7.6 33.4 8.5 4.9 5.7 74.3 1.2 9.8 7.7 7.6 2.0 3.1 25.4 5.9 3.7 21.3 22.7 0.9 0.3 0.0 0.0 0.0 37.9 0.0 0.2 0.3 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 49.6 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 22.4 11.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.1 0.2 0.2 1.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.4 1.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.2 1.8 0.3 2.3 2.2 1.0 2.5 1.1 2.0 1.2 2.0 0.9 11.8 3.2 2.2 1.0 8.5 2.5 0.7 0.0 1.8 168.1 4.0 6.2 0.4 2.8 0.7 0.0 0.0 1.1 0.6 0.2 0.0 0.0 17.5 35.8 1279.3 38.9 0.0 5.3 1.2 0.6 1.5 259.7 2.6 34.5 0.0 0.3 6.4 243.0 122.0 0.0 123.9 0.0 16.2 25.8 12.5 58.0 1103.2 42.0 14.2 27.2 3.6 4.4 0.0 0.5 0.9 0.1 0.0 193.4 66.9 1.2 0.0 1.4 0.1 9.0 0.0 139.3 19.6 1.9 1.2 1.6 2.7 1.2 9.1 69.4 0.2 0.4 IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2141238 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 2749.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1104.3;Extravillous trophoblasts: 3196.3;Leydig cells: 3007.5;Peritubular cells: 643.9;Syncytiotrophoblasts: 1612.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 86.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 862.0;Hep G2: 600.5;LHCN-M2: 333.7;RH-30: 408.5;SH-SY5Y: 495.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007556, HPA007993" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 609000000 1200000000 "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "HPA007556: AB_2667860, HPA007993: AB_1851474" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" 99.7 58.4 5.5 9.2 32.6 0.9 41.8 12.6 86.0 75.5 236.8 22.3 4.7 75.2 52.7 18.8 128.4 34.8 91.7 6.5 7.1 31.8 305.9 9.8 3.4 20.2 6.6 117.8 37.5 5.2 25.4 2749.2 10.1 14.5 4.8 0.5 11.6 15.2 82.1 8.4 10.9 14.7 13.0 14.4 11.9 23.7 10.9 3.4 12.4 114.0 4.7 24.2 23.6 9.0 0.0 2.8 0.3 0.6 0.2 0.3 1.8 112.8 1.3 3.6 0.4 862.0 0.4 0.1 8.4 0.0 2.1 0.1 0.9 7.0 7.9 0.1 0.5 0.2 0.2 600.5 143.4 0.7 0.0 174.7 0.5 0.7 0.2 0.1 1.4 0.0 0.3 0.0 333.7 2.2 0.1 0.8 1.2 0.2 1.5 0.1 408.5 0.9 0.0 0.9 32.7 495.6 0.7 0.1 0.0 83.0 4.2 0.0 0.4 0.2 20.1 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 32.6 12.6 86.0 6.5 7.1 20.2 6.6 10.1 13.0 10.9 9.0 40.6 3.2 3.1 0.0 2.6 5.4 0.5 0.5 0.6 0.4 0.0 0.0 6.5 8.6 0.9 3.7 0.0 1104.3 0.0 0.0 0.0 0.0 13.1 0.0 0.0 498.4 0.0 16.0 0.0 0.0 3196.3 334.2 0.0 0.0 0.0 0.0 171.4 494.9 218.2 0.0 0.0 0.0 0.0 11.6 5.5 91.1 3007.5 3.4 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 643.9 0.0 1.1 0.0 0.0 0.9 0.5 65.7 33.5 37.5 3.8 6.3 1.5 4.1 1612.9 1.8 0.0 0.0 0.4 IGF2R "CD222, CI-M6PR, CI-MPR, CIMPR, M6P-R, MPR1, MPR300, MPRI" ENSG00000197081 "Insulin like growth factor 2 receptor" P11717 6 159969082-160113507 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 69.5" "Cell type enhanced" "Detected in many" "NK-cells: 264.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009661, HPA011332" Supported Enhanced "Golgi apparatus,Vesicles" NA NA 190000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus, Vesicles" "CAB009661: AB_2122795, HPA011332: AB_1846276" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (2.92e-5)" "unprognostic (5.83e-2)" "unprognostic (1.72e-1)" "unprognostic (4.15e-1)" "unprognostic (3.25e-1)" "unprognostic (7.32e-3)" "unprognostic (2.32e-1)" "unprognostic (1.62e-1)" "unprognostic (1.07e-2)" "unprognostic (2.37e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-3)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (6.08e-4)" 20.3 21.9 1.8 11.4 3.7 13.3 16.0 3.9 4.3 15.2 11.7 17.4 7.4 19.3 4.8 16.7 13.9 10.7 21.8 3.2 4.2 14.8 23.9 22.2 8.2 4.3 3.6 17.0 16.6 14.3 9.5 15.3 3.8 11.0 11.6 3.2 18.4 6.7 69.5 16.5 14.7 16.0 3.2 23.2 15.5 7.7 4.8 15.9 14.5 27.2 7.8 15.3 16.5 5.9 20.8 18.1 32.6 44.6 108.4 76.4 36.9 30.1 80.4 30.3 52.8 28.3 37.2 7.3 30.9 38.4 101.7 25.4 27.0 140.0 52.0 47.7 19.4 3.6 30.0 32.1 49.2 20.7 31.2 52.7 45.4 57.6 144.8 65.4 19.2 36.0 42.2 48.2 46.4 10.1 8.8 13.4 13.1 19.3 23.2 23.2 20.6 46.1 29.9 20.8 11.3 25.4 45.0 34.5 44.8 41.4 15.7 49.4 25.3 27.0 27.9 57.3 60.4 16.7 40.2 9.1 49.0 23.7 38.9 0.5 1.0 0.8 1.1 0.3 0.4 0.2 0.5 0.4 0.2 0.2 0.5 0.7 4.4 0.7 0.4 1.3 0.2 0.3 1.8 3.7 3.9 4.3 3.2 4.2 4.3 3.6 3.8 3.2 4.8 5.9 44.7 48.1 47.3 34.6 16.7 22.2 10.0 16.0 17.1 13.0 20.2 14.7 33.6 24.3 22.1 16.5 20.9 7.5 107.0 46.2 0.0 29.3 7.5 25.8 38.7 29.6 22.3 9.5 33.0 19.4 12.3 29.9 16.8 39.7 3.8 41.7 28.9 63.4 22.2 15.2 34.2 18.4 12.2 59.4 12.8 5.2 47.5 37.6 12.4 31.9 65.9 11.7 264.7 30.7 40.0 40.8 17.2 38.4 35.9 17.1 23.2 23.6 12.2 15.1 65.7 63.7 32.6 10.9 10.4 28.9 19.7 9.3 38.8 38.8 20.9 16.7 IGFALS ALS ENSG00000099769 "Insulin like growth factor binding protein acid labile subunit" P35858 16 1790413-1794971 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 116.7" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 85.2" "Cancer enhanced" "Detected in many" "liver cancer: 11.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 1.9;U-266/70: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA040692, HPA040948" Supported "Secreted to blood" NA NA 14700000000 26000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA040692: AB_10794067, HPA040948: AB_10794999" "unprognostic (2.74e-3)" "unprognostic (1.95e-1)" "unprognostic (9.13e-2)" "prognostic unfavorable (6.06e-4)" "unprognostic (2.54e-1)" "unprognostic (1.37e-2)" "prognostic favorable (5.97e-4)" "unprognostic (5.54e-4)" "unprognostic (3.00e-1)" "unprognostic (1.17e-1)" "unprognostic (9.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (4.39e-1)" "unprognostic (5.51e-2)" 0.3 0.2 0.5 0.3 0.9 0.4 0.4 1.4 0.8 0.5 0.9 0.6 0.3 0.2 0.1 0.1 0.7 1.6 0.2 0.3 0.1 1.0 116.7 0.8 0.0 0.7 0.4 0.7 2.5 0.0 0.7 0.0 0.8 0.5 0.1 0.2 0.8 0.1 0.5 0.9 0.6 0.0 0.4 0.3 11.0 1.9 0.4 0.9 0.9 0.0 0.0 0.4 0.2 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.5 0.0 0.0 1.7 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 1.4 0.8 0.3 0.1 0.7 0.4 0.8 0.4 0.4 1.8 0.1 0.0 0.0 1.6 0.1 0.1 0.2 0.2 0.0 0.5 0.9 0.6 1.6 14.3 0.2 0.0 6.2 0.0 0.0 0.6 0.0 2.7 1.1 0.4 0.0 0.2 0.0 0.0 0.5 0.6 0.0 0.4 8.2 0.1 0.0 0.2 2.9 85.2 0.0 0.0 0.6 14.6 0.0 1.3 0.3 1.7 0.0 0.0 1.8 0.0 0.0 0.3 1.0 0.0 0.7 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.9 0.0 0.2 0.1 0.4 0.4 0.0 0.3 0.0 0.2 0.1 0.7 0.1 IGFBP1 "AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12" ENSG00000146678 "Insulin like growth factor binding protein 1" P08833 7 45888360-45893660 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 1198.4" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 994.8" "Cancer enriched" "Detected in many" 29 "liver cancer: 385.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Hep G2: 54.7;U-2197: 84.9;U-87 MG: 145.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004445, HPA046972, HPA050640" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 28100000 25000000 "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "CAB004445: AB_627782, HPA046972: AB_2679884, HPA050640: AB_2681197" "unprognostic (8.66e-3)" "unprognostic (1.45e-1)" "unprognostic (9.41e-2)" "unprognostic (7.80e-2)" "unprognostic (7.04e-2)" "unprognostic (2.93e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.89e-2)" "unprognostic (2.09e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (6.90e-11)" "prognostic unfavorable (6.64e-4)" "unprognostic (7.20e-2)" "unprognostic (7.98e-2)" "unprognostic (3.43e-1)" 2.6 0.1 0.2 0.0 0.2 0.0 2.4 0.2 0.3 0.3 0.1 0.0 0.3 79.6 0.1 0.0 4.1 0.3 0.5 0.2 0.3 1.6 1198.4 0.1 0.1 0.8 0.3 46.3 0.5 0.0 0.5 204.5 0.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.5 0.1 0.1 0.3 1.1 0.3 0.0 0.0 0.0 0.2 0.2 0.2 6.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.6 0.3 1.4 0.1 1.6 0.3 0.0 0.0 0.7 0.0 0.0 0.3 0.5 54.7 0.3 1.1 0.1 0.1 0.7 11.3 0.1 0.6 0.3 0.0 0.2 0.1 1.3 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.3 0.0 2.2 0.0 0.3 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 84.9 0.0 0.0 0.0 0.2 145.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.3 0.8 0.3 0.9 0.2 0.3 0.2 0.4 0.0 0.5 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 5.7 1.0 35.8 0.7 0.0 0.0 0.9 0.0 0.0 0.0 11.0 0.1 4.7 94.3 0.9 3.5 10.7 0.1 0.0 1.6 1.8 0.0 15.9 0.0 2.1 6.8 994.8 1.7 0.0 0.1 0.0 0.0 14.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.1 0.5 0.0 0.0 3.4 0.8 0.0 0.0 0.0 IGFBP2 IBP2 ENSG00000115457 "Insulin like growth factor binding protein 2" P18065 2 216632828-216664436 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 956.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1379.1;Granulosa cells: 1649.7;Hepatocytes: 658.6;Theca cells: 2199.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2139.8;HMC-1: 5110.0;NB-4: 1106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077723 Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 303000000 810000000 "Cluster 48: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "HPA077723: AB_2686853" "unprognostic (2.58e-1)" "unprognostic (5.95e-2)" "unprognostic (1.94e-1)" "unprognostic (3.32e-3)" "unprognostic (9.50e-3)" "unprognostic (2.36e-2)" "unprognostic (2.06e-1)" "unprognostic (9.11e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (1.82e-1)" "prognostic unfavorable (2.22e-5)" "unprognostic (5.04e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (1.22e-1)" 219.5 58.8 15.9 28.3 14.8 21.4 90.5 15.6 30.2 86.9 123.3 85.5 76.8 232.5 59.9 145.6 157.0 26.9 169.2 15.6 16.3 187.3 607.7 71.0 8.8 15.3 21.7 281.7 956.0 12.4 66.9 81.0 19.3 217.3 35.0 2.4 76.4 196.2 23.3 30.8 44.6 49.7 13.2 398.9 492.2 58.0 16.0 33.6 57.8 21.9 14.5 132.6 97.4 13.2 0.1 52.3 402.1 396.3 2139.8 652.9 8.5 125.2 61.9 6.1 0.6 1.2 1.5 0.1 171.7 0.8 15.2 11.5 145.4 156.9 0.6 0.8 84.9 91.3 0.2 26.3 53.3 38.6 5110.0 219.3 15.8 2.5 7.1 12.5 0.2 184.7 3.9 11.7 2.8 103.1 162.8 1106.5 437.4 98.2 4.8 139.2 9.1 2.0 2.0 117.1 84.1 443.4 0.3 3.4 2.6 362.2 332.4 67.3 0.5 1.6 2.4 1.6 6.2 6.2 0.9 9.7 6.0 177.4 478.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 15.9 14.8 15.6 30.2 15.6 16.3 15.3 21.7 19.3 13.2 16.0 13.2 354.3 3.2 0.6 2.0 3.3 13.8 534.0 238.2 19.4 0.2 79.0 498.0 12.5 11.5 40.1 264.8 2.1 1.8 5.4 86.4 29.4 3.0 1.0 153.2 1379.1 149.2 321.0 31.1 4.5 128.4 7.7 296.7 411.8 176.0 4.5 1649.7 92.1 658.6 5.3 0.0 0.8 191.6 54.9 24.1 5.0 4.9 5.6 21.8 3.6 13.1 1.3 3.6 3.1 1.0 1.0 60.7 51.3 79.4 0.4 255.7 4.2 1.2 195.9 1.7 105.2 17.9 435.7 6.0 35.8 103.3 5.5 2.2 16.0 2199.1 133.8 304.0 IGFBP3 "BP-53, IBP3" ENSG00000146674 "Insulin like growth factor binding protein 3" P17936 7 45912245-45921874 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 1864.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 457.7;Basal respiratory cells: 777.7;Extravillous trophoblasts: 2064.1;Fibroblasts: 463.4;Urothelial cells: 809.9" "Cancer enhanced" "Detected in all" "renal cancer: 377.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 54.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 54.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 8578.6;U-2197: 3469.4;U-87 MG: 1774.2" "Low region specificity" "Detected in all" CAB010360 Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3250000000 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB010360: AB_2233528" "unprognostic (4.46e-3)" "unprognostic (4.84e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.30e-1)" "unprognostic (1.15e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (8.14e-3)" "unprognostic (3.31e-2)" "unprognostic (2.03e-1)" "unprognostic (9.67e-3)" "unprognostic (2.80e-1)" "prognostic unfavorable (5.07e-7)" "unprognostic (2.36e-2)" "unprognostic (4.14e-2)" "unprognostic (2.37e-3)" "unprognostic (2.63e-1)" 350.6 16.2 15.6 28.5 20.2 1.2 278.2 12.2 24.1 291.8 18.9 96.7 67.8 547.3 43.1 28.2 130.9 44.6 284.6 16.5 22.5 65.9 721.3 37.5 68.3 20.7 13.7 233.1 14.4 28.0 98.1 1864.4 21.0 87.4 58.4 11.9 46.2 81.1 57.9 176.5 77.9 198.1 12.8 191.0 81.7 10.8 16.5 18.2 40.8 73.3 67.4 369.7 165.3 15.9 199.6 59.5 113.1 1.0 83.9 34.7 0.9 850.6 153.8 71.9 38.8 0.2 157.4 0.2 263.2 8578.6 35.6 466.5 1.5 3.4 29.2 0.6 0.1 0.3 20.8 0.2 21.9 0.4 1.6 285.7 12.8 15.1 53.8 112.3 0.7 0.0 0.1 3.2 26.8 1.2 1.3 1.4 7.8 1.8 10.9 0.8 0.4 81.4 53.2 423.6 13.6 32.7 293.9 11.4 15.3 250.6 1.5 0.7 0.5 815.4 1.7 3469.4 49.3 11.6 0.7 1.1 1774.2 0.3 282.1 0.0 0.0 0.0 10.1 0.0 8.0 0.0 10.9 10.7 0.0 0.0 4.9 8.1 0.1 0.0 0.0 54.5 0.8 4.5 15.6 20.2 12.2 24.1 16.5 22.5 20.7 13.7 21.0 12.8 16.5 15.9 260.4 3.2 3.9 0.7 1.9 457.7 148.9 777.7 8.0 2.8 12.6 30.4 12.6 8.6 409.7 228.1 0.0 94.1 10.0 0.7 11.7 145.6 1.3 32.3 220.1 168.0 273.7 5.3 2.5 2.0 2064.1 463.4 1.5 31.3 1.3 12.2 182.0 2.6 80.9 0.0 5.6 8.4 57.0 7.2 21.9 3.5 288.3 3.5 16.0 1.9 7.2 0.6 0.0 0.5 0.2 19.0 2.5 6.8 1.0 212.1 0.8 1.0 136.0 0.5 0.0 12.6 124.6 0.8 1.4 9.3 244.6 154.2 9.3 3.6 2.0 809.9 IGFBP4 "BP-4, HT29-IGFBP, IBP4, IGFBP-4" ENSG00000141753 "Insulin like growth factor binding protein 4" P22692 17 40443450-40457725 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 672.7;Endometrial stromal cells: 542.2;Endothelial cells: 502.3;Fibroblasts: 585.4;Hepatic stellate cells: 566.5;Hepatocytes: 501.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 19.5;NK-cell: 37.0" "Group enriched" "Detected in many" 5 "NK-cells: 37.0;T-cells: 19.5" "Cell line enhanced" "Detected in many" "A549: 1334.8;ASC diff: 961.5;ASC TERT1: 933.8;BJ: 1066.4;BJ hTERT+: 1088.2;HSkMC: 2001.2;U-2197: 882.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066240 Supported "Secreted to blood" NA NA 227000000 410000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA066240: AB_2685643" "unprognostic (1.03e-3)" "unprognostic (1.61e-1)" "unprognostic (1.85e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.44e-3)" "unprognostic (1.00e-1)" "prognostic favorable (5.49e-4)" "unprognostic (4.55e-2)" "unprognostic (1.19e-2)" "unprognostic (2.28e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (2.72e-5)" "unprognostic (6.23e-2)" "unprognostic (1.73e-1)" "unprognostic (2.36e-1)" "unprognostic (3.81e-2)" 884.7 248.1 26.0 307.7 26.9 2.4 754.6 25.3 46.5 1020.7 65.0 618.0 82.8 795.8 141.9 246.7 791.1 391.4 502.9 25.6 28.2 464.4 1475.9 390.1 60.0 29.5 34.1 1270.4 164.4 44.6 203.7 231.8 28.9 470.0 133.5 13.1 264.4 279.0 107.3 241.7 289.5 645.1 28.3 295.5 369.6 67.7 35.3 38.9 501.4 97.4 44.2 552.1 576.2 25.8 0.2 1334.8 66.8 0.5 961.5 933.8 2.2 1066.4 1088.2 199.7 154.4 59.7 17.3 0.3 563.7 511.0 27.2 11.9 22.6 6.8 90.2 4.8 1.3 4.3 91.3 89.9 601.2 2.9 0.5 2001.2 4.6 267.7 37.7 23.8 350.6 0.1 21.7 0.2 290.5 41.2 0.8 252.5 37.2 58.9 178.2 67.2 1.3 2.1 8.4 42.1 18.3 53.0 482.3 2.0 17.0 63.5 486.6 24.7 534.7 276.0 14.4 882.1 1.1 0.9 0.6 1.7 163.8 9.9 72.4 0.0 0.0 0.0 2.7 0.0 19.5 0.8 5.0 6.7 0.0 5.2 0.3 0.6 0.0 37.0 0.0 0.2 0.0 1.4 26.0 26.9 25.3 46.5 25.6 28.2 29.5 34.1 28.9 28.3 35.3 25.8 672.7 9.6 37.4 1.3 17.6 56.3 97.1 36.7 79.1 3.2 118.9 163.2 16.9 90.1 16.2 7.3 0.0 6.1 10.6 93.3 17.6 4.1 6.7 69.8 542.2 502.3 8.4 37.9 3.8 2.4 7.2 585.4 13.7 59.1 2.5 230.9 566.5 501.2 273.6 1.7 3.4 74.7 4.1 42.8 94.0 16.5 246.4 21.3 72.9 18.7 3.4 3.8 1.0 1.0 0.3 39.1 72.1 118.5 7.4 63.8 71.6 204.7 18.5 1.1 190.7 13.8 299.9 1.9 8.2 26.8 47.7 7.5 20.3 25.9 109.0 73.6 IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695549 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1492.5;ovary: 1323.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 1104.1;Ionocytes: 980.6;Leydig cells: 1828.2;Peritubular cells: 981.7;Sertoli cells: 1275.3;Skeletal myocytes: 2750.9;Smooth muscle cells: 1376.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 831.3;BJ hTERT+: 2192.6;T-47d: 531.7;U-138 MG: 710.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059827, HPA070407" Supported Approved "Nuclear bodies,Golgi apparatus,Vesicles" "Secreted to blood" NA NA 110000000 380000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "Nuclear bodies" "HPA059827: AB_2732640, HPA070407: " "unprognostic (7.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (1.12e-1)" "unprognostic (2.41e-2)" "unprognostic (4.04e-2)" "unprognostic (9.62e-3)" "unprognostic (1.55e-1)" "unprognostic (3.28e-2)" "unprognostic (1.91e-3)" 375.1 221.8 35.6 178.2 35.1 0.7 354.6 21.9 30.9 1492.5 46.9 232.3 35.0 837.7 121.3 166.4 953.0 129.3 155.0 50.4 41.8 479.1 34.2 78.2 71.3 36.3 37.9 1323.4 30.7 30.7 272.8 290.7 31.5 241.4 66.2 105.4 111.0 121.8 470.9 129.0 139.3 621.2 28.1 38.7 323.5 28.8 43.8 95.0 326.2 292.9 45.9 259.2 382.9 62.4 0.0 0.0 210.6 0.9 237.1 7.5 0.8 831.3 2192.6 108.8 10.4 0.0 1.0 0.1 3.3 2.3 0.0 0.1 26.2 0.0 5.6 0.1 8.2 218.1 4.4 0.2 103.1 0.1 1.8 33.1 0.0 14.7 0.1 24.8 0.1 0.2 0.7 0.1 0.5 70.9 0.9 1.2 2.3 0.0 3.4 0.3 0.8 1.2 70.3 249.1 14.5 8.5 14.6 100.4 0.0 12.8 531.7 0.1 80.3 710.2 42.2 109.3 41.0 0.7 0.1 0.1 1.4 0.1 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.6 35.1 21.9 30.9 50.4 41.8 36.3 37.9 31.5 28.1 43.8 62.4 237.3 3.2 4.4 40.1 20.6 102.5 13.5 211.0 25.0 8.7 73.9 199.9 92.0 5.7 251.6 112.2 6.2 3.9 1.7 0.0 5.9 10.3 8.4 140.2 250.7 120.8 0.0 0.0 6.0 0.0 4.5 1104.1 30.5 128.5 2.5 11.4 49.6 1.4 8.7 3.3 13.7 0.0 980.6 0.6 189.7 39.9 1828.2 18.4 101.4 29.0 0.6 674.4 0.0 5.5 0.4 2.2 0.0 981.7 5.5 17.0 0.0 1.1 120.9 18.7 1275.3 2750.9 1376.0 2.2 3.0 17.7 67.9 5.6 18.4 124.7 0.1 16.8 IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 580.8;Fibroblasts: 1360.5;Leydig cells: 1030.8;Peritubular cells: 1495.9;Sertoli cells: 1170.1;Smooth muscle cells: 420.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 145.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.6;non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 1163.6;BJ: 476.9;BJ hTERT+: 683.3;fHDF/TERT166: 1045.9;hTERT-RPE1: 468.5;U-87 MG: 631.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 120.2" "HPA008005, HPA075088" Uncertain "Secreted to blood" NA NA 199000000 300000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA008005: AB_1851499, HPA075088: " "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" 145.8 90.2 28.1 9.2 32.6 0.4 150.5 31.8 40.8 276.6 71.6 75.5 20.8 117.2 129.5 75.8 237.4 36.8 107.0 28.4 33.1 30.6 7.7 40.4 8.7 32.7 29.2 136.8 15.9 4.8 106.3 15.7 33.2 129.3 28.0 6.6 35.9 122.2 38.5 39.2 52.5 39.0 36.7 45.2 67.6 22.2 41.7 6.8 58.4 102.2 9.2 127.1 214.1 27.2 135.3 219.6 0.2 177.3 313.9 1163.6 0.8 476.9 683.3 126.9 69.0 23.2 294.7 0.0 68.5 1045.9 96.4 453.3 3.0 42.3 26.2 1.2 2.8 4.4 37.1 33.3 111.9 0.8 1.1 325.5 2.3 57.4 11.9 468.5 30.5 7.5 0.6 9.3 53.1 0.5 6.6 1.0 6.8 4.1 150.4 2.3 4.9 5.6 10.1 3.3 1.3 8.7 152.2 0.0 10.9 4.0 6.3 0.5 132.2 87.2 41.2 95.5 18.0 5.3 10.7 0.6 631.6 6.7 49.5 0.0 0.0 31.6 0.6 6.8 3.4 0.1 1.0 5.4 2.1 0.0 0.5 6.8 0.0 0.0 20.1 0.0 0.0 1.5 28.1 32.6 31.8 40.8 28.4 33.1 32.7 29.2 33.2 36.7 41.7 27.2 83.9 6.4 4.2 2.0 3.4 113.6 41.0 580.8 23.9 2.5 5.9 29.0 21.1 10.0 37.6 20.2 0.0 3.0 3.5 0.2 11.7 87.9 9.6 4.9 99.2 71.9 0.0 3.2 3.1 8.0 4.9 1360.5 30.5 2.5 0.0 2.3 116.4 0.8 7.6 0.0 3.6 0.3 50.8 6.8 122.8 32.6 1030.8 15.2 144.1 19.7 2.5 51.1 0.0 1.5 0.9 77.1 0.0 1495.9 9.6 94.9 0.0 15.2 13.9 2.8 1170.1 102.3 420.9 3.8 6.8 8.0 87.8 3.4 14.1 0.4 0.0 34.1 IGFBP7 "FSTL2, IGFBP-7, MAC25, PSF" ENSG00000163453 "Insulin like growth factor binding protein 7" Q16270 4 57030773-57110385 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 11440.4;Peritubular cells: 11731.6;Sertoli cells: 8184.6;Smooth muscle cells: 4434.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 21.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 693.6;BJ hTERT+: 643.1;hTERT-RPE1: 1471.3;RPTEC TERT1: 682.7;TIME: 1009.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002196, CAB020668" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 30300000 190000000 "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "CAB020668: , HPA002196: AB_1079107" "unprognostic (2.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.82e-2)" "unprognostic (5.97e-3)" "unprognostic (3.86e-1)" "unprognostic (3.18e-1)" "unprognostic (2.96e-3)" "unprognostic (1.02e-1)" "unprognostic (2.62e-1)" "unprognostic (1.01e-2)" "unprognostic (2.57e-1)" "unprognostic (6.65e-2)" "unprognostic (2.28e-1)" "unprognostic (2.62e-3)" "unprognostic (1.78e-1)" "unprognostic (3.58e-1)" "unprognostic (7.55e-2)" 833.0 374.9 99.4 151.1 124.0 44.2 583.2 112.7 149.7 640.3 1299.1 473.1 105.6 653.2 260.4 115.3 618.1 405.7 1117.2 132.7 143.8 1298.6 283.2 532.4 133.1 185.2 138.7 359.1 270.1 77.2 246.0 66.6 146.4 506.0 83.2 4.7 193.7 659.0 185.6 193.6 259.6 334.9 136.8 436.9 267.4 259.2 187.9 48.9 995.3 91.8 81.9 546.4 494.0 132.6 1.3 4.8 1.1 0.0 134.8 50.4 4.7 693.6 643.1 59.2 19.0 2.8 0.1 0.3 433.7 33.5 35.3 70.2 0.7 111.1 15.7 1.3 5.4 2.5 78.7 0.5 207.7 17.1 17.9 234.7 55.8 96.8 26.2 1471.3 138.2 0.6 0.5 0.9 142.8 0.0 0.5 74.5 5.9 0.0 1.3 13.4 0.4 2.8 682.7 0.0 1.0 1.8 130.2 9.5 0.0 276.3 1.8 64.6 1009.4 60.5 46.4 7.8 114.8 41.1 0.4 1.4 159.2 58.3 1.8 2.0 3.9 21.7 0.1 4.1 0.1 0.0 0.0 0.0 10.7 0.0 0.0 0.1 0.3 10.8 4.5 0.4 0.1 1.7 99.4 124.0 112.7 149.7 132.7 143.8 185.2 138.7 146.4 136.8 187.9 132.6 2254.8 112.2 20.2 164.9 16.2 238.5 127.2 300.5 24.5 5.9 27.7 53.5 148.2 20.0 90.6 2087.4 22.9 6.6 76.9 1.4 516.5 2455.3 75.9 1235.5 702.2 2740.1 1.2 82.7 0.7 15.1 8.3 1435.9 29.0 381.3 15.8 1205.0 3079.4 16.4 26.5 0.0 3.7 1.0 61.1 101.9 375.7 335.4 11440.4 70.4 944.5 151.8 41.8 17.1 345.0 11.6 0.8 84.6 1.5 11731.6 11.0 113.3 0.0 692.2 731.0 12.5 8184.6 155.0 4434.0 36.6 38.6 9.9 179.1 5.7 51.3 759.1 2.5 64.0 IGFBPL1 bA113O24.1 ENSG00000137142 "Insulin like growth factor binding protein like 1" Q8WX77 9 38406528-38424454 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "thyroid gland: 16.5" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 1.8;Excitatory neurons: 2.5;Hofbauer cells: 1.9;Inhibitory neurons: 1.6;Oligodendrocyte precursor cells: 2.5;Spermatogonia: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 360.4;NTERA-2: 104.2;RH-30: 97.5;SCLC-21H: 334.3;SH-SY5Y: 332.6;SuSa: 241.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051354 Uncertain Uncertain Nucleoplasm,Vesicles "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "HPA051354: " "unprognostic (5.63e-2)" "unprognostic (3.33e-1)" "unprognostic (5.22e-2)" "unprognostic (2.42e-1)" "unprognostic (2.56e-2)" "unprognostic (1.92e-1)" "unprognostic (1.30e-1)" "unprognostic (5.66e-2)" "unprognostic (2.26e-1)" "unprognostic (3.05e-1)" "unprognostic (2.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (3.94e-1)" "unprognostic (3.92e-2)" "unprognostic (1.59e-2)" "unprognostic (6.67e-2)" 0.8 1.5 2.4 0.5 4.2 0.5 0.1 3.4 2.8 0.2 1.4 0.5 0.9 0.7 0.1 0.3 0.3 0.6 1.3 2.6 2.0 0.2 0.3 0.8 0.2 1.5 2.3 0.1 0.9 0.0 1.1 0.6 1.7 0.4 0.3 0.3 0.1 1.6 0.2 0.2 0.6 1.1 1.0 0.1 1.6 2.1 2.8 2.9 16.5 0.0 0.1 0.5 0.1 1.8 0.0 8.6 360.4 0.4 0.0 0.0 0.2 2.4 0.0 0.5 0.3 0.1 0.2 0.1 1.3 0.3 0.0 0.1 44.0 0.0 0.5 0.0 2.7 0.1 1.2 0.2 0.0 1.7 1.2 0.4 0.0 0.0 0.0 0.2 0.0 1.6 0.2 0.2 2.5 0.1 0.3 0.2 104.2 0.5 0.7 0.1 97.5 0.9 0.0 0.2 334.3 332.6 6.4 0.5 0.0 241.3 2.3 2.3 0.4 0.1 7.7 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.5 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.2 0.1 0.0 2.4 4.2 3.4 2.8 2.6 2.0 1.5 2.3 1.7 1.0 2.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.3 0.6 0.1 0.0 1.8 0.0 2.5 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 IGFL1 UNQ644 ENSG00000188293 "IGF like family member 1" Q6UW32 19 46229742-46231243 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 113.0;salivary gland: 34.5;vagina: 31.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.7;Basal respiratory cells: 12.5;Prostatic glandular cells: 4.4;Squamous epithelial cells: 2.1;Suprabasal keratinocytes: 3.4" "Group enriched" "Detected in many" 7 "cervical cancer: 47.6;head and neck cancer: 60.7;melanoma: 23.3;urothelial cancer: 84.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 6.9;RT4: 25.6;SK-BR-3: 8.6" HPA014001 Uncertain "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA014001: AB_2668919" "unprognostic (1.35e-1)" "unprognostic (9.70e-2)" "unprognostic (2.89e-1)" "unprognostic (1.01e-1)" "unprognostic (1.64e-2)" "unprognostic (2.67e-2)" "unprognostic (3.06e-1)" "unprognostic (4.50e-3)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (1.80e-1)" "unprognostic (1.64e-1)" "unprognostic (3.23e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 6.7 0.0 0.0 0.0 0.0 0.0 113.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 34.5 0.0 0.0 3.5 0.0 0.0 0.0 0.3 0.1 1.0 0.0 0.8 0.0 0.0 4.8 0.4 31.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 6.9 0.0 1.9 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.2 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 12.5 0.0 0.0 0.5 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 4.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.4 0.3 2.1 3.4 0.0 0.0 0.0 0.0 0.2 IGFL2 UNQ645 ENSG00000204866 "IGF like family member 2" Q6UWQ7 19 46143106-46161299 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 41.6" "Cell type enhanced" "Detected in some" "Astrocytes: 17.9;Excitatory neurons: 27.1;Inhibitory neurons: 29.3;Oligodendrocytes: 38.5;Spermatocytes: 9.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 65 "CACO-2: 82.4;OE19: 166.9" HPA059137 Uncertain Approved "Nucleoplasm,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Plasma membrane" "HPA059137: AB_2683920" "unprognostic (1.53e-1)" "unprognostic (7.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.69e-2)" "unprognostic (7.30e-2)" "unprognostic (9.74e-2)" "unprognostic (1.92e-1)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (1.68e-1)" "unprognostic (4.26e-3)" "unprognostic (9.63e-3)" "unprognostic (4.14e-9)" "unprognostic (1.27e-1)" "unprognostic (2.76e-2)" "unprognostic (8.73e-2)" "unprognostic (9.91e-3)" 2.4 0.0 0.2 0.0 0.2 0.0 2.0 0.0 0.8 0.1 0.0 0.5 0.0 0.2 0.5 1.5 0.1 0.0 0.2 0.2 0.4 0.0 0.0 0.3 2.0 0.7 0.3 0.0 0.0 1.5 0.3 0.9 0.8 0.0 0.8 0.4 1.0 0.0 0.0 41.6 0.1 0.2 0.2 0.0 0.0 4.1 0.3 1.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 1.7 0.5 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.3 0.0 0.0 1.6 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 166.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.8 0.2 0.4 0.7 0.3 0.8 0.2 0.3 2.1 0.0 0.0 0.0 17.9 0.0 2.2 0.0 1.1 0.0 1.7 2.0 1.5 0.6 0.0 0.7 0.0 0.0 4.3 0.0 0.7 0.0 0.0 8.7 0.0 0.0 0.2 0.0 0.0 27.1 0.2 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 29.3 0.4 0.0 0.0 0.3 5.4 0.0 0.0 1.8 0.0 0.0 0.2 0.0 6.0 38.5 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.0 1.9 0.0 0.0 0.7 9.8 8.7 0.0 4.7 2.6 0.2 0.0 1.4 0.0 IGFL3 UNQ483 ENSG00000188624 "IGF like family member 3" Q6UXB1 19 46120067-46124688 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 27.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.1;Basal respiratory cells: 1.7;Exocrine glandular cells: 6.5;Melanocytes: 1.8;Suprabasal keratinocytes: 8.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.7;CACO-2: 1.0;hTEC/SVTERT24-B: 1.2;U-2 OS: 1.3;U-87 MG: 2.4" HPA062776 Uncertain "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 28: Keratinocytes - Keratinization" "HPA062776: AB_2684866" "unprognostic (8.61e-2)" "unprognostic (6.26e-2)" "unprognostic (2.69e-1)" "unprognostic (4.78e-2)" "unprognostic (7.45e-3)" "unprognostic (2.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.90e-1)" "unprognostic (1.86e-4)" "unprognostic (2.86e-2)" "unprognostic (1.90e-1)" "unprognostic (3.69e-2)" 0.0 0.0 0.6 0.0 1.2 0.1 1.5 0.0 1.2 0.0 0.0 0.1 0.2 0.1 0.3 0.0 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.1 0.0 1.1 0.2 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.1 0.5 0.1 0.0 0.3 27.7 0.0 0.1 0.2 0.0 0.0 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.2 0.2 1.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.2 1.2 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 1.2 0.5 0.3 1.1 0.2 1.1 0.2 0.4 2.6 0.0 0.0 0.0 0.0 0.0 3.1 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 6.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.4 1.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 IGFLR1 "FLJ22573, TMEM149, U2AF1L4" ENSG00000126246 "IGF like family receptor 1" Q9H665 19 35738801-35742453 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 49.9" "Cell type enhanced" "Detected in many" "dendritic cells: 29.9;granulocytes: 38.7;Langerhans cells: 33.7;Macrophages: 28.8;monocytes: 115.6;Plasma cells: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 899.7" "Lineage enriched" "Detected in all" 4 "dendritic cells: 899.7" "Cell line enhanced" "Detected in many" "HMC-1: 32.9;Karpas-707: 26.0;U-266/70: 34.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA012369, HPA070778" Uncertain Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Plasma membrane" "HPA012369: AB_1858095, HPA070778: " "unprognostic (5.97e-3)" "prognostic favorable (6.55e-4)" "unprognostic (1.94e-1)" "unprognostic (5.42e-2)" "unprognostic (8.31e-3)" "unprognostic (2.34e-4)" "unprognostic (6.71e-2)" "unprognostic (1.74e-2)" "unprognostic (1.87e-2)" "prognostic favorable (1.59e-5)" "unprognostic (1.44e-3)" "unprognostic (3.52e-1)" "unprognostic (8.72e-12)" "unprognostic (2.74e-1)" "unprognostic (1.22e-1)" "unprognostic (2.29e-1)" "unprognostic (3.32e-3)" 7.6 10.9 6.1 19.5 6.8 14.4 6.2 6.0 9.3 4.9 6.0 6.5 6.1 3.4 5.5 4.0 6.4 6.1 4.5 5.9 11.1 14.0 49.9 11.3 33.0 9.1 6.8 4.4 9.3 1.4 5.5 4.5 7.4 6.2 6.4 4.6 7.8 1.5 4.5 4.4 13.2 4.4 5.6 28.6 7.9 6.7 7.1 12.6 7.2 2.1 23.2 7.3 3.5 7.5 2.2 10.0 3.5 8.3 1.1 1.7 2.0 1.5 1.1 1.8 4.7 3.0 2.4 4.0 3.2 0.7 0.6 1.6 2.0 2.1 0.9 3.3 5.0 15.0 3.4 9.1 2.8 1.7 32.9 2.7 1.3 3.5 0.8 0.6 1.9 7.7 4.9 26.0 0.5 7.4 5.1 16.7 1.6 9.4 2.7 6.0 3.3 8.3 1.7 3.2 2.4 4.5 3.4 2.4 1.8 1.3 3.4 7.8 0.5 4.2 2.0 2.6 4.0 34.0 7.5 2.8 4.9 5.8 3.0 147.9 190.9 184.1 94.2 167.7 106.6 169.3 107.3 88.8 253.2 172.1 95.8 77.0 208.6 144.9 125.3 899.7 136.3 139.5 6.1 6.8 6.0 9.3 5.9 11.1 9.1 6.8 7.4 5.6 7.1 7.5 0.3 0.0 13.5 2.6 24.5 0.6 0.3 0.0 0.0 0.4 1.3 1.3 1.2 1.5 5.0 0.0 0.0 0.6 29.9 1.2 1.9 1.9 0.0 0.8 0.6 0.8 3.0 6.1 0.3 4.2 1.8 0.9 1.1 0.7 38.7 0.6 2.2 20.3 14.6 0.0 0.4 1.8 0.0 15.7 33.7 0.6 0.0 28.8 5.4 1.9 115.6 2.7 12.3 2.5 1.0 1.4 0.3 0.0 42.1 0.2 0.9 10.8 3.6 0.4 0.0 1.0 0.9 0.4 0.5 1.9 0.9 0.3 20.8 0.4 2.4 0.0 IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 486.7;salivary gland: 234.3" "Cell type enriched" "Detected in some" 259 "Plasma cells: 13773.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.2" "Lineage enriched" "Detected in many" 21 "B-cells: 73.2" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HL-60: 3.0;RPMI-8226: 2.9;TIME: 1.6" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.47e-4)" "unprognostic (2.53e-2)" "unprognostic (8.73e-3)" "unprognostic (2.56e-2)" "unprognostic (9.67e-3)" "prognostic favorable (8.27e-4)" "unprognostic (5.47e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (3.60e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.84e-7)" "unprognostic (3.22e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" 22.0 3.5 0.0 0.0 0.3 0.0 22.9 0.0 0.6 54.6 0.0 223.2 0.0 8.9 4.5 162.5 24.3 7.7 2.3 0.0 0.0 16.2 14.3 58.3 0.0 0.6 0.1 8.5 3.2 1.9 1.3 0.2 0.4 10.8 0.0 0.0 234.3 0.0 0.4 1.3 103.2 2.6 0.0 486.7 84.0 0.5 0.1 0.0 33.9 0.2 0.0 156.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 0.6 0.5 0.8 0.0 0.0 1.1 1.2 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 1.0 0.5 0.0 0.3 0.0 1.4 0.0 3.4 0.0 0.1 0.0 0.0 0.1 73.2 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.6 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 50.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.5 53.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 13773.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 3.2 0.0 0.1 0.0 IGHV1-2 V35 ENSG00000211934 "Immunoglobulin heavy variable 1-2" P23083 14 105986582-105987083 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 462.7;lymphoid tissue: 1157.3" "Cell type enriched" "Detected in some" 38 "Plasma cells: 609.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 52 "memory B-cell: 285.2;naive B-cell: 347.4" "Lineage enriched" "Detected in many" 57 "B-cells: 347.4" "Cell line enriched" "Detected in some" 8 "U-266/70: 14302.7" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.63e-3)" "unprognostic (1.09e-3)" "unprognostic (1.88e-1)" "unprognostic (9.46e-2)" "unprognostic (5.78e-2)" "prognostic favorable (1.67e-5)" "unprognostic (9.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (1.99e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (2.17e-2)" "unprognostic (8.59e-2)" "unprognostic (3.19e-1)" "unprognostic (1.17e-2)" 16.7 43.1 0.3 364.1 0.2 76.0 84.1 0.0 1.2 41.5 0.5 462.7 223.7 13.1 1.3 34.5 58.5 54.4 26.2 0.0 0.1 13.7 18.9 60.7 404.9 0.4 0.0 36.5 3.0 0.6 1.3 0.6 0.2 23.2 283.8 0.0 222.4 52.5 0.4 4.5 121.9 7.5 0.2 393.2 216.1 35.0 0.1 72.1 33.7 0.0 1157.3 255.5 8.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 4.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 2.6 0.0 0.0 2.3 0.4 2.8 0.0 0.0 3.1 0.6 0.5 0.0 0.0 1.3 1.8 0.1 0.0 0.6 0.0 0.0 0.2 0.3 0.0 1.5 0.0 1.3 14302.7 1755.5 0.5 0.0 0.4 0.0 0.3 0.6 0.1 0.3 0.0 0.2 285.2 1.6 0.7 0.2 347.4 1.5 0.6 6.1 0.2 0.3 0.5 1.1 34.0 0.3 0.2 0.0 1.2 0.0 0.1 0.4 0.0 0.2 0.2 0.1 0.6 0.0 0.0 1.3 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 609.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 IGHV1-24 ENSG00000211950 "Immunoglobulin heavy variable 1-24" A0A0C4DH33 14 106276548-106277043 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 186.8;salivary gland: 76.3" "Cell type enriched" "Detected in some" 4 "Plasma cells: 231.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.8" "Lineage enriched" "Detected in single" 9 "B-cells: 2.8" "Cell line enhanced" "Detected in some" "Daudi: 1.0;HL-60: 1.8;JURKAT: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 3100000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.01e-4)" "unprognostic (2.67e-2)" "unprognostic (1.66e-2)" "unprognostic (1.93e-3)" "prognostic favorable (3.61e-4)" "unprognostic (1.28e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.59e-1)" "unprognostic (4.10e-1)" "prognostic unfavorable (2.07e-7)" "unprognostic (5.43e-2)" "unprognostic (3.14e-2)" "unprognostic (3.17e-1)" "unprognostic (4.78e-2)" 6.8 1.4 0.1 33.7 0.0 0.0 8.5 0.0 0.3 56.3 0.1 30.5 0.0 5.7 0.0 46.2 6.5 4.6 1.8 0.0 0.1 7.0 6.4 17.7 0.0 1.2 0.1 19.6 1.4 0.1 0.4 0.3 0.0 3.1 14.0 0.0 76.3 0.0 0.1 0.8 24.0 2.1 0.0 186.8 37.0 14.2 0.0 0.4 14.5 0.0 18.4 63.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.8 0.1 0.0 0.0 2.8 0.1 0.2 0.0 0.0 0.0 0.0 0.1 3.6 0.1 0.0 0.0 0.3 0.0 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 19.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 231.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 5.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 629.4" "Cell type enriched" "Detected in some" 335 "Plasma cells: 13473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory B-cell: 52.8;naive B-cell: 27.8" "Lineage enriched" "Detected in many" 9 "B-cells: 52.8" "Cell line enriched" "Detected in some" 11 "Karpas-707: 148.5" "Immunoglobulin genes" NA NA 2600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-2)" "unprognostic (3.81e-3)" "unprognostic (2.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.41e-3)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (5.60e-2)" "unprognostic (3.07e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.67e-7)" "unprognostic (7.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-1)" "unprognostic (3.26e-1)" 10.6 59.3 0.0 207.8 0.0 36.4 46.7 0.0 0.5 41.6 0.3 193.3 218.5 4.8 15.3 45.5 6.5 85.4 3.2 0.0 0.1 8.2 8.9 40.9 171.8 0.2 0.0 8.4 7.0 0.3 0.6 0.1 0.1 6.0 223.2 0.0 120.6 23.5 0.6 0.9 140.9 11.2 0.0 246.6 189.1 0.4 0.1 57.8 24.2 0.0 629.4 92.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 14.1 1.0 148.5 0.0 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.7 0.7 0.0 0.0 10.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.7 0.0 2.8 1.4 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 52.8 0.6 0.2 0.0 27.8 1.6 0.5 0.0 0.0 0.0 5.8 1.7 6.1 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13473.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 4.5 0.0 0.0 0.0 IGHV1-45 ENSG00000211961 "Immunoglobulin heavy variable 1-45" A0A0A0MS14 14 106506996-106507491 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 18.9;lymphoid tissue: 30.3;stomach 1: 17.5" "Cell type enriched" "Detected in single" 20 "Plasma cells: 2.0" "Cancer enriched" "Detected in many" 7 "lung cancer: 15.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "U-266/70: 1.2;U-266/84: 1.3" "Immunoglobulin genes" NA NA 380000000 "Cluster 32: T-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.57e-4)" "unprognostic (5.07e-3)" "unprognostic (2.12e-3)" "unprognostic (1.46e-1)" "unprognostic (7.64e-3)" "unprognostic (2.90e-1)" "unprognostic (3.50e-2)" "unprognostic (3.16e-1)" "unprognostic (1.48e-1)" "unprognostic (1.05e-1)" "unprognostic (4.05e-1)" "unprognostic (1.28e-3)" "unprognostic (2.94e-2)" "unprognostic (2.87e-1)" "unprognostic (2.32e-1)" "unprognostic (3.16e-1)" 0.2 0.1 0.0 3.7 0.0 1.8 18.9 0.0 0.0 0.3 0.0 4.5 1.1 0.5 0.0 6.4 0.2 0.6 0.1 0.0 0.0 0.2 0.2 3.5 7.6 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 6.1 0.0 11.5 0.0 0.0 0.1 2.3 0.7 0.0 6.9 17.5 0.1 0.0 2.9 0.3 0.0 30.3 4.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 1.1 0.6 0.3 0.0 1.1 0.7 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.9;lymphoid tissue: 125.7;salivary gland: 67.4" "Cell type enriched" "Detected in some" 201 "Plasma cells: 8432.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;RPMI-8226: 1.2;SH-SY5Y: 1.2;TIME: 2.3;U-266/70: 1.1;U-266/84: 1.2" "Immunoglobulin genes" NA NA 2900000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.28e-4)" "unprognostic (2.49e-2)" "prognostic favorable (7.34e-4)" "unprognostic (1.10e-2)" "unprognostic (3.53e-2)" "unprognostic (1.80e-3)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (8.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-1)" "prognostic unfavorable (1.56e-6)" "unprognostic (6.19e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.13e-1)" 5.1 1.3 0.0 0.0 0.0 0.0 7.2 0.0 0.1 6.2 0.0 67.9 0.0 2.5 1.0 4.9 3.5 0.7 5.0 0.0 0.0 3.2 4.2 15.3 0.0 0.1 0.0 3.0 5.3 0.1 0.3 0.3 0.1 1.9 45.1 0.0 67.4 0.0 0.1 0.7 34.2 0.0 0.0 125.7 25.1 0.2 0.0 0.0 10.5 0.2 0.0 5.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 0.5 1.2 0.2 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.1 1.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.0 0.0 0.0 1.9 41.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8432.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 IGHV1-58 ENSG00000211968 "Immunoglobulin heavy variable 1-58" A0A0C4DH39 14 106622357-106622855 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "urinary bladder: 204.7" "Group enriched" "Detected in some" 17 "B-cells: 2.4;Plasma cells: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 8.7;naive B-cell: 12.7" "Lineage enriched" "Detected in single" 58 "B-cells: 12.7" "Cell line enhanced" "Detected in single" "MOLT-4: 1.5" "Immunoglobulin genes" NA NA 120000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (9.63e-3)" "unprognostic (6.78e-2)" "unprognostic (5.64e-2)" "unprognostic (4.04e-2)" "prognostic favorable (7.25e-4)" "unprognostic (4.56e-2)" "unprognostic (1.21e-1)" "unprognostic (4.62e-1)" "unprognostic (1.46e-2)" "unprognostic (4.89e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (3.24e-2)" "unprognostic (5.28e-2)" "unprognostic (6.79e-2)" "unprognostic (1.36e-1)" 8.1 3.4 0.0 13.8 0.0 5.9 3.8 0.0 0.0 0.8 0.0 19.5 15.7 0.4 0.0 8.3 1.1 4.7 1.0 0.0 0.0 1.5 1.4 5.4 41.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.4 27.8 0.0 23.5 1.9 0.0 0.2 9.8 0.1 0.0 26.2 13.1 0.5 0.0 10.3 1.1 0.0 51.1 204.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-69 IGHV1-E ENSG00000211973 "Immunoglobulin heavy variable 1-69" P01742 14 106714684-106715181 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 139.1;lymphoid tissue: 170.2;urinary bladder: 162.6" "Cell type enriched" "Detected in some" 85 "Plasma cells: 231.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 22 "medulla oblongata: 2.5;pons: 3.0" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 1.4;HMC-1: 1.0;MOLT-4: 6.2;SCLC-21H: 1.1;U-698: 1.9" "Immunoglobulin genes" NA NA 2700000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.51e-3)" "unprognostic (7.03e-2)" "prognostic favorable (9.56e-5)" "prognostic favorable (8.32e-4)" "unprognostic (1.06e-2)" "unprognostic (1.69e-1)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.64e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (1.28e-1)" "unprognostic (2.95e-1)" "unprognostic (8.20e-2)" "unprognostic (6.82e-2)" 7.7 1.4 0.0 0.0 0.1 0.1 6.5 0.0 0.0 21.4 0.1 56.9 0.0 6.9 0.0 7.0 5.7 77.4 0.7 0.0 0.1 7.0 4.8 18.0 0.0 2.5 0.0 2.0 0.8 1.8 0.5 0.0 3.0 4.6 139.1 0.0 55.9 13.0 0.1 0.5 31.7 6.8 0.0 170.2 31.0 0.1 0.0 0.0 25.2 0.0 0.0 162.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 1.3 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 231.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-69-2 IGHV1-F ENSG00000281990 "Immunoglobulin heavy variable 1-69-2" A0A0G2JMI3 14 106737110-106737547 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.1;lymphoid tissue: 47.1" "Cell type enriched" "Detected in some" 226 "Plasma cells: 10423.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 6.7;naive B-cell: 5.5" "Lineage enriched" "Detected in many" 6 "B-cells: 6.7" "Cell line enriched" "Detected in some" 6 "MOLT-4: 11.2" "Immunoglobulin genes" NA NA 1100000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" 6.3 0.3 0.0 5.8 0.0 2.5 3.6 0.0 0.0 1.5 0.0 12.0 22.1 1.1 0.2 2.1 1.2 14.5 1.6 0.0 0.0 2.7 0.9 4.5 13.5 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 14.4 0.0 16.4 0.9 0.0 0.0 18.0 0.2 0.0 47.1 9.9 0.2 0.0 3.7 1.1 0.0 36.5 4.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 6.7 0.5 0.9 0.0 5.5 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 1.4 23.0 0.0 0.0 0.0 1.1 1.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10423.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 IGHV1-69D ENSG00000280411 "Immunoglobulin heavy variable 1-69D" A0A0B4J2H0 14 106762092-106762588 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2878.6;stomach 1: 989.1" "Group enriched" "Detected in some" 6 "Plasma cells: 5.8;T-cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 225 "memory B-cell: 184.5;naive B-cell: 433.4" "Lineage enriched" "Detected in many" 316 "B-cells: 433.4" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HL-60: 2.3;MOLT-4: 4.2;RPMI-8226: 2.5;U-266/70: 3.3;U-698: 7.9" "Immunoglobulin genes" NA NA 1200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (3.32e-3)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (2.49e-4)" "prognostic favorable (2.88e-4)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.72e-8)" "unprognostic (5.14e-2)" "unprognostic (9.96e-2)" "unprognostic (2.84e-2)" "unprognostic (2.08e-2)" 26.1 95.3 0.1 462.7 0.1 113.1 146.7 0.0 0.7 37.5 1.0 628.2 491.2 15.0 16.8 98.6 16.0 78.0 20.2 0.0 0.1 17.5 46.6 149.6 2878.6 1.1 0.0 35.9 3.3 0.6 1.1 0.4 0.1 16.5 406.2 0.0 385.0 100.0 0.5 5.2 121.3 43.8 0.2 452.7 989.1 6.8 0.0 135.7 38.3 0.0 2219.2 295.4 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.2 0.3 1.3 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.6 0.4 3.3 0.1 7.9 0.0 0.7 0.0 0.8 0.3 0.1 0.0 0.0 0.2 184.5 0.3 0.0 0.2 433.4 0.4 0.1 0.4 0.2 0.4 1.3 0.2 33.5 0.1 0.1 0.0 0.7 0.0 0.1 1.1 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGHV1OR15-1 IGHV1/OR15-1 ENSG00000270505 "Immunoglobulin heavy variable 1/OR15-1 (non-functional)" 15 22160431-22160868 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 78.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.0;B-cells: 1.1;granulocytes: 1.3;T-cells: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 94.3;naive B-cell: 111.6" "Group enriched" "Detected in many" 18 "B-cells: 111.6;T-cells: 60.9" "Group enriched" "Detected in some" 4 "JURKAT: 10.3;Karpas-707: 6.9;MOLT-4: 2.5" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (2.14e-1)" "unprognostic (1.13e-1)" 0.6 0.4 0.0 18.2 0.1 7.0 5.8 0.1 0.1 0.8 0.0 15.6 13.8 0.8 0.0 4.0 0.6 14.4 0.6 0.0 0.1 0.4 0.7 2.8 52.0 0.2 0.1 1.0 0.4 0.1 0.1 0.1 0.1 2.3 10.2 0.0 4.8 0.4 0.0 0.1 13.7 0.4 0.2 18.1 11.1 0.1 0.1 58.7 1.1 0.0 78.8 9.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 6.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 9.2 0.0 3.3 94.3 54.9 18.1 0.1 111.6 60.9 14.5 0.5 4.8 0.1 3.3 35.9 20.5 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.0 3.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.2 0.0 IGHV1OR15-9 "IGHV1/OR15-9, IGHV1OR159, VSIG7" ENSG00000188403 "Immunoglobulin heavy variable 1/OR15-9 (non-functional)" 15 19964666-19965101 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "breast: 4.1;intestine: 8.6;lymphoid tissue: 8.6;stomach 1: 8.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 14: B-cells - Humoral immune response" "prognostic favorable (1.79e-4)" "unprognostic (8.93e-2)" "unprognostic (2.97e-3)" "unprognostic (9.34e-2)" "prognostic favorable (6.84e-4)" "unprognostic (1.64e-1)" "unprognostic (1.57e-1)" "unprognostic (3.79e-1)" "unprognostic (1.07e-4)" "unprognostic (3.68e-2)" "unprognostic (1.91e-1)" "unprognostic (2.66e-1)" "unprognostic (2.11e-1)" 0.0 0.0 0.0 8.6 0.0 0.0 4.1 0.0 0.0 0.0 0.0 8.6 3.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 8.3 0.0 0.0 1.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1OR21-1 IGHV1/OR21-1 ENSG00000277282 "Immunoglobulin heavy variable 1/OR21-1 (non-functional)" 21 10649400-10649835 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.3;lymphoid tissue: 6.3;stomach 1: 3.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 2.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "memory B-cell: 2.0;naive B-cell: 1.7" "Lineage enriched" "Detected in single" 15 "B-cells: 2.0" "Cell line enhanced" "Detected in single" "U-266/70: 1.1" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "unprognostic (3.93e-3)" "unprognostic (2.55e-2)" "unprognostic (1.28e-2)" "unprognostic (8.48e-5)" "unprognostic (2.59e-1)" "unprognostic (3.45e-1)" "unprognostic (1.53e-2)" "unprognostic (1.00e-1)" "unprognostic (3.32e-1)" 0.0 0.6 0.0 3.3 0.0 0.2 0.3 0.0 0.0 0.0 0.0 3.3 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 1.4 0.6 0.0 0.9 3.4 0.1 0.0 0.5 0.0 0.0 6.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV2-26 ENSG00000211951 "Immunoglobulin heavy variable 2-26" A0A0B4J1V2 14 106301396-106301862 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 128.8;lymphoid tissue: 98.5;urinary bladder: 227.1" "Group enriched" "Detected in some" 39 "B-cells: 8.3;Plasma cells: 7.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 14 "memory B-cell: 13.9" "Lineage enriched" "Detected in single" 140 "B-cells: 13.9" "Cell line enhanced" "Detected in some" "HL-60: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 190000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 57: B-cells - Immune response" "unprognostic (9.39e-3)" "unprognostic (4.50e-2)" "unprognostic (7.66e-3)" "unprognostic (2.94e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-2)" "unprognostic (1.18e-1)" "unprognostic (1.67e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" "unprognostic (4.99e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (6.68e-2)" "unprognostic (2.61e-1)" "unprognostic (2.24e-1)" "unprognostic (8.09e-2)" 6.2 7.7 0.0 59.0 0.0 21.6 14.0 0.0 0.3 15.5 0.2 35.0 61.5 4.2 0.0 31.5 3.8 128.8 5.6 0.0 0.4 2.3 6.0 20.7 3.5 0.2 0.6 0.5 1.6 0.0 0.3 0.0 0.1 6.3 86.5 0.0 44.2 0.9 0.1 0.5 55.1 4.4 0.2 98.5 65.1 0.0 1.1 0.0 6.8 0.0 21.8 227.1 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.2 1.1 0.2 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 465.8;lymphoid tissue: 1426.6;stomach 1: 707.9" "Cell type enriched" "Detected in some" 333 "Plasma cells: 9414.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory B-cell: 66.7;naive B-cell: 67.3" "Lineage enriched" "Detected in many" 22 "B-cells: 67.3" "Cell line enriched" "Detected in some" 5 "Karpas-707: 8.8" "Immunoglobulin genes" NA NA 700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (6.62e-3)" "prognostic favorable (1.41e-4)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.63e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" 16.9 5.0 0.0 183.0 0.2 112.8 106.0 0.0 0.5 45.0 0.2 465.8 266.6 7.5 2.5 27.9 10.7 65.0 5.8 0.0 0.1 20.9 16.4 83.9 188.0 0.5 0.2 13.8 9.3 1.0 1.1 0.3 0.7 9.4 296.3 0.0 201.4 8.8 0.4 2.9 177.0 17.4 0.3 351.0 707.9 2.3 0.0 121.5 27.6 0.0 1426.6 249.3 12.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.6 0.4 0.0 0.1 1.2 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.4 0.6 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 66.7 0.0 0.0 0.1 67.3 0.1 0.1 3.0 0.0 0.0 0.0 0.0 10.5 0.0 0.2 0.0 0.5 0.0 0.1 0.5 0.2 0.7 0.3 0.0 0.4 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.1 27.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9414.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 IGHV2-70 ENSG00000274576 "Immunoglobulin heavy variable 2-70" P01814 14 106770577-106771020 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 727.6;stomach 1: 502.1" "Cell type enriched" "Detected in single" 5 "Plasma cells: 2.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Group enriched" "Detected in some" 241 "memory B-cell: 24.6;naive B-cell: 23.5" "Lineage enriched" "Detected in single" 247 "B-cells: 24.6" "Cell line enriched" "Detected in some" 8 "U-698: 12.4" "Immunoglobulin genes" NA NA 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.01e-3)" "unprognostic (2.93e-2)" "unprognostic (3.56e-3)" "unprognostic (2.38e-2)" "unprognostic (1.12e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (9.10e-2)" "unprognostic (2.50e-1)" "unprognostic (8.93e-2)" "unprognostic (2.91e-1)" 7.3 25.7 0.0 96.2 0.0 69.2 86.1 0.0 5.2 62.3 0.0 86.7 53.2 4.1 0.0 44.3 8.1 37.5 2.5 0.0 1.4 4.8 13.2 69.9 82.7 0.1 1.1 5.0 1.0 0.9 0.3 0.2 0.1 6.8 82.8 0.0 94.5 14.1 0.1 0.9 42.1 2.5 2.2 156.4 502.1 1.2 0.0 59.5 8.5 0.0 727.6 50.4 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.4 0.8 0.0 0.0 0.8 0.6 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.7 0.0 0.1 0.0 12.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 5.2 0.0 1.4 0.1 1.1 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV2-70D ENSG00000211974 "Immunoglobulin heavy variable 2-70D" A0A0C4DH43 14 106723574-106724093 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.8;lymphoid tissue: 90.8;stomach 1: 47.0" "Cell type enriched" "Detected in single" 10 "B-cells: 1.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 68 "memory B-cell: 9.7;naive B-cell: 3.7" "Lineage enriched" "Detected in single" 97 "B-cells: 9.7" "Cell line enriched" "Detected in single" 7 "MOLT-4: 1.7" "Immunoglobulin genes" NA NA 110000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (5.57e-2)" "unprognostic (9.48e-3)" "prognostic favorable (3.34e-4)" "unprognostic (4.34e-2)" "unprognostic (8.37e-3)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (6.70e-2)" "unprognostic (3.83e-1)" "unprognostic (3.66e-2)" "unprognostic (8.11e-2)" 1.7 0.7 0.0 16.6 0.0 4.1 7.1 0.0 0.0 5.6 0.1 36.8 14.2 1.9 0.0 5.2 4.5 20.9 1.7 0.0 0.0 2.5 2.3 6.2 4.6 0.0 0.0 0.8 0.3 0.1 0.1 0.0 0.0 0.7 33.1 0.0 30.3 0.1 0.0 0.1 21.7 0.6 0.0 41.4 47.0 0.0 0.0 4.5 2.5 0.0 90.8 3.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV2OR16-5 IGHV2/OR16-5 ENSG00000259303 "Immunoglobulin heavy variable 2/OR16-5 (non-functional)" 16 32847713-32848156 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "epididymis: 4.7;intestine: 1.8;lymphoid tissue: 3.2;salivary gland: 1.4;stomach 1: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "AN3-CA: 2.6;HMC-1: 1.6" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "unprognostic (1.93e-1)" "unprognostic (1.15e-1)" 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 1.7 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.5 0.0 1.4 0.0 0.0 0.1 1.8 0.0 0.0 0.3 5.2 0.0 0.0 0.0 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 220.1;lymphoid tissue: 613.1;stomach 1: 206.7" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1655.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 445 "memory B-cell: 43.1;naive B-cell: 45.7" "Lineage enriched" "Detected in single" 458 "B-cells: 45.7" "Cell line enhanced" "Detected in some" "Daudi: 1.1;SH-SY5Y: 1.2" "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.07e-3)" "unprognostic (4.84e-2)" "unprognostic (5.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-2)" "prognostic favorable (3.42e-5)" "unprognostic (4.12e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-2)" "unprognostic (3.51e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" 9.3 25.9 0.0 175.0 0.0 38.0 66.0 0.0 0.5 34.7 0.2 220.1 193.4 6.8 12.3 38.6 6.6 43.7 8.6 0.0 0.0 6.8 10.5 29.1 123.7 0.8 0.0 7.8 2.0 0.2 0.8 0.0 0.1 4.0 167.9 0.0 119.7 3.7 0.3 0.7 116.8 11.2 0.1 219.2 206.7 1.3 0.4 44.9 17.0 0.0 613.1 109.4 8.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1655.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-13 ENSG00000211942 "Immunoglobulin heavy variable 3-13" P01766 14 106129540-106130072 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.5;lymphoid tissue: 137.3;urinary bladder: 90.5" "Group enriched" "Detected in some" 6 "B-cells: 6.7;Plasma cells: 13.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 193 "memory B-cell: 18.8;naive B-cell: 19.6" "Lineage enriched" "Detected in single" 197 "B-cells: 19.6" "Cell line enhanced" "Detected in some" "MOLT-4: 1.8;U-266/70: 1.0" "Immunoglobulin genes" NA NA 33000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (3.24e-4)" "unprognostic (7.42e-2)" "unprognostic (1.96e-2)" "unprognostic (5.03e-2)" "prognostic favorable (6.67e-6)" "unprognostic (5.44e-2)" "unprognostic (1.23e-2)" "unprognostic (1.53e-1)" "unprognostic (5.31e-2)" "unprognostic (8.27e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (7.21e-5)" "unprognostic (6.79e-2)" "unprognostic (3.21e-1)" "unprognostic (4.45e-1)" "unprognostic (7.87e-2)" 1.3 36.6 0.0 24.1 0.0 6.9 17.2 0.0 0.1 1.9 0.0 67.5 49.5 1.5 0.0 15.4 4.3 9.7 1.8 0.0 0.0 1.1 1.5 7.2 39.5 0.0 0.1 1.5 0.7 0.0 0.1 0.0 0.0 1.1 36.1 0.0 30.9 1.4 0.0 0.1 22.8 5.6 0.1 56.5 42.9 0.9 0.0 9.3 2.8 0.0 137.3 90.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-15 ENSG00000211943 "Immunoglobulin heavy variable 3-15" A0A0B4J1V0 14 106153624-106154163 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 183.3;lymphoid tissue: 380.2;salivary gland: 177.7;stomach 1: 112.8;urinary bladder: 172.6" "Cell type enriched" "Detected in some" 112 "Plasma cells: 6281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "MAIT T-cell: 21.6;memory B-cell: 24.4" "Group enriched" "Detected in many" 9 "B-cells: 24.4;T-cells: 21.6" "Cell line enhanced" "Detected in some" "BEWO: 2.2;Daudi: 1.9;HL-60: 2.1;K-562: 2.0;NB-4: 2.4;RH-30: 1.9;RPMI-8226: 4.1;SH-SY5Y: 3.7" "Immunoglobulin genes" NA NA 20000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.85e-5)" "unprognostic (2.07e-1)" "unprognostic (1.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "prognostic favorable (3.34e-5)" "unprognostic (5.20e-2)" "unprognostic (2.44e-1)" "unprognostic (9.67e-2)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (6.85e-2)" "unprognostic (6.92e-2)" "unprognostic (7.12e-2)" "unprognostic (3.63e-1)" 12.2 36.8 0.0 24.7 0.5 1.8 23.2 0.0 1.2 13.0 0.1 183.3 4.5 5.0 0.9 11.7 16.3 29.6 1.4 0.0 0.2 9.1 10.6 40.0 0.0 1.0 0.0 5.8 19.1 0.4 1.3 0.4 0.3 9.5 14.6 0.0 177.7 23.0 0.8 4.2 107.2 0.3 0.0 380.2 112.8 0.5 0.0 0.0 14.9 0.0 10.4 172.6 9.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.8 2.4 0.7 0.0 0.0 0.0 1.9 4.1 0.0 0.0 0.0 3.7 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 1.6 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.1 0.1 0.0 21.6 24.4 0.1 0.2 0.2 0.0 0.2 0.1 2.5 0.0 0.0 0.2 0.1 1.8 0.0 0.5 0.0 1.2 0.0 0.2 1.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.1 1.1 0.6 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6281.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 IGHV3-16 ENSG00000211944 "Immunoglobulin heavy variable 3-16 (non-functional)" A0A0C4DH30 14 106165205-106165730 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 3200000000 "Cluster 43: B-cells - Humoral immune response" "unprognostic (1.04e-1)" "unprognostic (1.04e-1)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.2;lymphoid tissue: 216.6;stomach 1: 122.5;urinary bladder: 81.9" "Cell type enriched" "Detected in some" 24 "Plasma cells: 142.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 242 "memory B-cell: 28.5;naive B-cell: 19.8" "Lineage enriched" "Detected in single" 286 "B-cells: 28.5" "Cell line enhanced" "Detected in single" "Daudi: 1.2" "Immunoglobulin genes" NA NA 2200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.56e-5)" "unprognostic (2.30e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.93e-4)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.09e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" 2.8 2.1 0.0 36.3 0.2 22.6 23.7 0.0 0.1 17.4 0.2 64.8 99.2 1.8 0.0 10.1 2.2 20.7 3.1 0.0 0.0 1.5 4.7 10.5 58.0 0.1 0.0 2.7 0.4 0.1 0.2 0.0 0.0 1.2 62.5 0.0 43.1 1.4 0.0 0.3 37.7 2.0 0.0 59.6 122.5 1.1 0.0 16.6 2.8 0.0 216.6 81.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 142.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 209.7;lymphoid tissue: 398.1;salivary gland: 213.2" "Cell type enriched" "Detected in some" 86 "Plasma cells: 3885.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.1;NB-4: 2.1;NTERA-2: 1.2;RH-30: 2.3;TIME: 1.9" "Immunoglobulin genes" NA NA 37000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.30e-4)" "unprognostic (1.21e-2)" "unprognostic (7.19e-3)" "unprognostic (1.51e-2)" "unprognostic (9.16e-3)" "prognostic favorable (9.34e-4)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (4.05e-1)" "prognostic unfavorable (9.31e-8)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" 18.1 2.7 0.3 0.0 0.3 0.0 24.8 0.2 1.1 16.8 0.3 209.7 0.0 7.1 0.9 17.4 30.9 0.0 2.0 0.2 0.3 15.4 10.7 55.3 0.0 0.4 0.3 2.9 16.2 2.3 1.3 0.6 0.4 7.2 0.0 0.0 213.2 0.3 0.4 4.3 111.3 0.8 0.4 398.1 83.0 0.4 0.3 0.0 25.6 0.0 0.0 27.7 10.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 2.1 1.2 0.0 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.2 1.1 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 1.0 21.4 0.0 0.0 0.1 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3885.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGHV3-23 ENSG00000211949 "Immunoglobulin heavy variable 3-23" P01764 14 106268606-106269140 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1683.1;lymphoid tissue: 2989.8" "Cell type enriched" "Detected in some" 139 "Plasma cells: 15979.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 406 "memory B-cell: 548.5;naive B-cell: 336.7" "Lineage enriched" "Detected in many" 503 "B-cells: 548.5" "Cell line enhanced" "Detected in some" "BEWO: 4.4;HL-60: 3.3;NB-4: 4.1;RH-30: 3.0;RPMI-8226: 9.0;SH-SY5Y: 5.8" "Immunoglobulin genes" NA NA 42000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (5.43e-2)" "unprognostic (9.68e-3)" "unprognostic (3.31e-3)" "unprognostic (1.34e-2)" "prognostic favorable (3.85e-4)" "unprognostic (3.26e-1)" "unprognostic (4.79e-1)" "unprognostic (7.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.79e-7)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-1)" "unprognostic (6.42e-2)" 66.5 189.3 0.4 912.2 0.4 185.5 343.1 0.1 2.1 80.1 1.5 1683.1 1640.8 37.0 9.8 342.6 30.1 231.2 46.4 0.1 0.3 27.3 56.4 248.7 859.5 0.8 0.1 42.6 31.0 1.5 2.7 0.9 0.4 35.3 1087.1 0.1 697.8 53.4 0.9 15.0 886.8 40.0 0.8 802.7 1058.8 35.0 0.2 197.5 52.3 0.1 2989.8 993.6 27.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 4.1 0.7 0.0 0.0 0.6 3.0 9.0 0.0 0.0 2.7 5.8 0.8 0.1 0.0 0.0 0.0 0.0 1.8 0.0 1.3 1.3 1.1 1.5 0.0 0.3 0.0 0.9 0.0 0.4 0.4 0.1 0.2 0.0 0.1 548.5 0.2 0.3 0.3 336.7 0.1 0.2 1.0 0.2 0.2 0.2 0.8 62.4 0.4 0.4 0.1 2.1 0.1 0.3 0.8 0.1 0.4 0.8 0.2 1.4 0.1 0.0 0.0 0.0 114.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 12.0 0.0 0.0 0.0 1.6 19.4 0.0 1.3 0.0 1.8 2.0 0.2 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15979.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.1 0.0 IGHV3-30 ENSG00000270550 "Immunoglobulin heavy variable 3-30" "P01768, P0DP03" 14 106335082-106335613 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 534.0;lymphoid tissue: 1294.8;salivary gland: 459.9;stomach 1: 572.6;urinary bladder: 378.9" "Cell type enriched" "Detected in some" 184 "Plasma cells: 14426.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 409 "memory B-cell: 164.0;naive B-cell: 136.6" "Lineage enriched" "Detected in single" 446 "B-cells: 164.0" "Cell line enhanced" "Detected in some" "BEWO: 2.1;Daudi: 1.7;NB-4: 2.3;RPMI-8226: 1.7;SCLC-21H: 1.7;SH-SY5Y: 3.0;U-266/70: 1.3" "Immunoglobulin genes" NA NA 8500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.12e-3)" "unprognostic (5.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "unprognostic (1.72e-2)" "prognostic favorable (3.23e-5)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.94e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (6.96e-2)" 25.3 38.5 0.1 320.5 0.2 119.7 143.9 0.0 0.4 49.3 0.5 534.0 265.5 13.3 0.0 134.6 44.8 146.5 30.3 0.4 0.2 29.2 25.1 128.2 374.9 0.6 0.2 23.0 12.3 0.7 3.3 0.7 0.2 18.6 254.9 0.0 459.9 20.4 0.9 3.5 296.1 23.6 0.1 797.4 572.6 5.9 0.1 158.2 76.6 0.1 1294.8 378.9 34.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 1.0 1.7 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 164.0 0.2 0.0 0.1 136.6 0.3 0.1 0.3 0.0 0.0 0.2 0.0 24.4 0.1 0.2 0.0 0.4 0.4 0.2 0.6 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.4 16.3 0.0 1.3 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14426.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.4 0.0 IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1066.7;lymphoid tissue: 2371.2;stomach 1: 1778.8" "Cell type enriched" "Detected in some" 26 "Plasma cells: 556.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 101 "memory B-cell: 378.9;naive B-cell: 364.1" "Lineage enriched" "Detected in many" 103 "B-cells: 378.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.4;HL-60: 5.3;RPMI-8226: 7.7;SH-SY5Y: 3.8;U-266/70: 8.1" "Immunoglobulin genes" NA NA 7500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.04e-3)" "unprognostic (2.38e-2)" "unprognostic (8.95e-3)" "prognostic favorable (6.36e-4)" "unprognostic (6.84e-2)" "prognostic favorable (7.19e-5)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-1)" "prognostic unfavorable (4.10e-6)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (3.26e-1)" "unprognostic (5.92e-2)" 27.9 67.4 1.0 513.8 0.8 117.8 289.5 0.2 4.0 53.6 2.4 1066.7 882.1 16.2 14.5 127.5 18.9 141.9 32.9 0.2 0.4 15.7 41.8 210.1 795.2 1.4 0.2 110.0 29.4 1.9 1.7 0.8 0.4 23.2 775.6 0.0 619.6 39.5 0.5 3.6 343.9 37.3 0.5 476.1 1778.8 29.4 0.7 296.8 42.2 0.1 2371.2 379.8 18.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 5.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 0.8 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.8 2.9 7.7 0.0 0.0 1.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 0.7 8.1 0.0 0.2 0.0 0.8 0.0 0.2 0.6 0.1 1.1 0.0 1.9 378.9 3.6 0.9 0.3 364.1 1.4 0.6 1.0 0.2 0.1 0.2 0.5 44.6 1.0 0.8 0.2 4.0 0.2 0.4 1.4 0.2 0.4 0.5 0.7 0.7 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.0 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 556.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-35 ENSG00000211957 "Immunoglobulin heavy variable 3-35 (non-functional)" A0A0C4DH35 14 106389392-106389858 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 14.1;lymphoid tissue: 12.8;salivary gland: 7.6;stomach 1: 16.7;urinary bladder: 20.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "memory B-cell: 3.7" "Lineage enriched" "Detected in single" 35 "B-cells: 3.7" "Cell line enriched" "Detected in single" 6 "MOLT-4: 1.3" "Immunoglobulin genes" NA NA 19000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-3)" "unprognostic (9.98e-2)" "unprognostic (1.16e-2)" "unprognostic (1.60e-2)" "prognostic favorable (2.53e-4)" "unprognostic (1.06e-1)" "unprognostic (4.74e-1)" "unprognostic (3.44e-1)" "unprognostic (2.37e-1)" "unprognostic (3.21e-1)" "unprognostic (4.29e-6)" "unprognostic (4.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" 0.1 0.1 0.0 12.8 0.0 3.3 1.1 0.0 0.0 2.8 0.0 10.3 14.1 0.4 0.0 0.5 1.1 1.1 0.5 0.0 0.0 0.1 0.7 2.4 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 11.1 0.0 7.6 0.5 0.0 0.2 6.0 0.6 0.0 5.3 16.7 0.0 0.0 0.0 0.0 0.0 2.2 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-38 ENSG00000211958 "Immunoglobulin heavy variable 3-38 (non-functional)" A0A0C4DH36 14 106410493-106411021 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.9;lymphoid tissue: 10.4;stomach 1: 5.9;urinary bladder: 7.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 3.4;naive B-cell: 1.5" "Lineage enriched" "Detected in single" 34 "B-cells: 3.4" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.03e-5)" "unprognostic (5.11e-2)" "unprognostic (3.29e-3)" "unprognostic (1.02e-1)" "unprognostic (1.31e-3)" "unprognostic (8.40e-2)" "unprognostic (3.54e-2)" "unprognostic (2.05e-1)" "unprognostic (1.98e-1)" "unprognostic (1.75e-8)" "unprognostic (6.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.99e-1)" "unprognostic (2.52e-1)" 0.3 0.1 0.0 5.9 0.0 1.6 3.3 0.0 0.0 1.4 0.0 7.7 9.9 0.1 0.0 0.9 0.1 0.9 0.2 0.0 0.0 0.1 0.4 1.8 2.2 0.0 0.0 0.6 0.4 0.0 0.0 0.2 0.0 0.2 7.0 0.0 4.1 0.0 0.0 0.2 5.8 0.0 0.0 4.4 5.9 0.7 0.0 0.0 0.0 0.0 10.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-43 ENSG00000232216 "Immunoglobulin heavy variable 3-43" A0A0B4J1X8 14 106470264-106470800 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 211.9;stomach 1: 312.2;urinary bladder: 153.0" "Cell type enriched" "Detected in some" 28 "Plasma cells: 557.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 321 "memory B-cell: 29.4;naive B-cell: 39.0" "Lineage enriched" "Detected in single" 366 "B-cells: 39.0" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.8;SH-SY5Y: 2.3" "Immunoglobulin genes" NA NA 4000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.31e-4)" "unprognostic (2.22e-2)" "prognostic favorable (1.46e-4)" "unprognostic (4.87e-3)" "prognostic favorable (8.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (4.63e-1)" "unprognostic (7.27e-3)" "unprognostic (4.50e-2)" "unprognostic (8.73e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.75e-2)" 9.3 2.3 0.0 23.7 0.3 11.5 43.7 0.0 0.3 46.0 0.0 101.8 102.5 2.0 0.0 10.2 3.5 10.7 0.4 0.0 0.0 2.7 9.8 10.8 4.3 0.7 0.0 4.2 2.2 1.0 0.3 0.1 0.2 2.7 66.1 0.0 58.1 5.4 0.1 1.0 48.3 4.4 0.0 83.7 312.2 0.2 0.1 0.0 3.8 0.0 211.9 153.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.5 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 557.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 IGHV3-48 ENSG00000211964 "Immunoglobulin heavy variable 3-48" P01763 14 106537810-106538344 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 516.4;lymphoid tissue: 858.8;stomach 1: 404.9" "Cell type enriched" "Detected in some" 100 "Plasma cells: 5878.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 527 "memory B-cell: 187.1;naive B-cell: 97.5" "Lineage enriched" "Detected in single" 693 "B-cells: 187.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.5;SH-SY5Y: 1.6" "Immunoglobulin genes" NA NA 49000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.19e-3)" "unprognostic (1.87e-2)" "unprognostic (5.12e-2)" "unprognostic (9.07e-3)" "unprognostic (1.77e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.23e-1)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (4.88e-8)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" 8.7 22.9 0.0 232.6 0.0 81.2 56.4 0.0 1.3 25.9 0.2 434.1 516.4 8.1 0.1 33.4 12.1 38.6 6.9 0.0 0.0 10.8 18.6 32.3 125.3 0.3 0.0 12.2 8.8 0.9 0.9 0.1 0.7 6.8 253.2 0.0 164.6 16.0 0.6 1.6 134.4 17.7 0.1 271.1 404.9 27.9 0.0 36.3 16.0 0.0 858.8 248.6 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.9 0.4 0.0 0.0 0.0 0.8 0.9 0.0 0.0 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 187.1 0.0 0.0 0.1 97.5 0.0 0.1 0.1 0.0 0.0 0.0 0.2 22.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 58.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.7 17.9 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5878.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 210.7;lymphoid tissue: 373.5;stomach 1: 182.3" "Cell type enriched" "Detected in some" 46 "Plasma cells: 717.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 187 "memory B-cell: 59.4;naive B-cell: 42.2" "Lineage enriched" "Detected in single" 219 "B-cells: 59.4" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" "Immunoglobulin genes" NA NA 1600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (7.16e-4)" "unprognostic (7.91e-3)" "unprognostic (2.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.34e-6)" "unprognostic (4.47e-2)" "unprognostic (4.30e-2)" "unprognostic (7.00e-3)" "unprognostic (9.17e-2)" "unprognostic (2.18e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.00e-1)" 20.8 7.1 0.0 112.3 0.0 45.7 42.5 0.0 0.5 11.5 0.3 210.7 184.4 4.6 3.9 20.0 5.1 10.9 9.4 0.0 0.2 5.0 12.8 43.2 108.6 0.7 0.0 26.5 1.7 0.2 0.4 0.0 0.3 3.0 139.3 0.0 88.5 12.1 0.2 0.4 88.2 11.5 0.1 183.1 182.3 1.8 0.1 21.4 9.7 0.0 373.5 100.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.4 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.4 0.0 0.0 0.0 42.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 717.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 IGHV3-53 ENSG00000211967 "Immunoglobulin heavy variable 3-53" P01767 14 106592676-106593347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.5;lymphoid tissue: 129.5;stomach 1: 43.3" "Cell type enriched" "Detected in some" 22 "Plasma cells: 176.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 99 "memory B-cell: 54.7;naive B-cell: 52.7" "Lineage enriched" "Detected in single" 101 "B-cells: 54.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.41e-3)" "unprognostic (1.12e-1)" "unprognostic (2.46e-3)" "prognostic favorable (5.66e-4)" "prognostic favorable (3.95e-4)" "unprognostic (3.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.04e-5)" "unprognostic (1.79e-1)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.72e-1)" 2.9 0.8 0.0 37.1 0.0 7.9 15.5 0.0 0.1 4.7 0.0 66.5 81.5 1.0 0.3 4.1 1.9 6.7 1.4 0.0 0.0 1.8 2.8 7.7 38.5 0.1 0.0 3.2 1.3 0.1 0.1 0.0 0.0 1.1 74.0 0.0 32.2 1.9 0.0 0.3 33.9 2.3 0.0 66.9 43.3 1.6 0.0 8.2 4.6 0.0 129.5 10.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 54.7 0.0 0.0 0.0 52.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV3-64 ENSG00000223648 "Immunoglobulin heavy variable 3-64" A0A075B6Q5 14 106657725-106658258 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.9;lymphoid tissue: 32.1;salivary gland: 21.0" "Cell type enriched" "Detected in some" 38 "Plasma cells: 88.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 19 "memory B-cell: 11.1" "Lineage enriched" "Detected in single" 111 "B-cells: 11.1" "Cell line enhanced" "Detected in single" "HL-60: 1.1" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.09e-6)" "unprognostic (6.52e-2)" "unprognostic (2.11e-3)" "unprognostic (3.10e-2)" "unprognostic (1.39e-3)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (8.01e-2)" "unprognostic (2.13e-2)" "unprognostic (2.33e-1)" "unprognostic (2.52e-1)" "prognostic unfavorable (3.93e-5)" "unprognostic (1.58e-1)" "unprognostic (1.85e-1)" "unprognostic (3.86e-2)" "unprognostic (1.07e-2)" 1.7 0.1 0.0 2.0 0.0 8.6 7.2 0.0 0.4 0.7 0.0 17.9 6.9 0.9 0.0 1.2 1.9 4.1 1.2 0.0 0.0 0.8 2.2 4.3 0.0 0.1 0.0 3.3 3.6 0.0 0.1 0.0 0.0 0.5 1.2 0.0 21.0 0.4 0.0 0.1 11.3 1.3 0.0 32.1 6.0 0.0 0.0 0.0 1.5 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-64D ENSG00000282639 "Immunoglobulin heavy variable 3-64D" A0A0J9YX35 14 106088122-106088573 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 145.2;lymphoid tissue: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 301 "memory B-cell: 43.3;naive B-cell: 18.7" "Lineage enriched" "Detected in single" 420 "B-cells: 43.3" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: Non-specific - Mitochondria" 8.3 0.5 0.2 140.3 0.1 10.9 84.2 0.0 0.8 12.9 0.3 130.9 20.4 3.3 1.4 35.4 7.8 46.3 4.8 0.5 0.0 1.5 4.2 36.7 48.8 0.1 0.0 5.1 8.1 0.1 0.1 0.1 0.0 4.1 145.2 0.0 28.9 11.5 0.0 3.8 68.8 3.6 0.1 67.4 74.8 0.5 0.0 16.5 2.9 0.0 272.7 40.5 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 0.2 0.1 0.0 0.8 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-66 ENSG00000211972 "Immunoglobulin heavy variable 3-66" A0A0C4DH42 14 106675017-106675544 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.3;intestine: 59.5;urinary bladder: 103.9" "Cell type enriched" "Detected in some" 107 "Plasma cells: 958.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "memory B-cell: 39.7" "Lineage enriched" "Detected in single" 137 "B-cells: 39.7" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.7;U-2 OS: 2.3" "Immunoglobulin genes" NA NA 7200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.43e-6)" "unprognostic (2.48e-2)" "unprognostic (5.05e-3)" "unprognostic (1.31e-3)" "unprognostic (2.20e-3)" "unprognostic (8.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.83e-2)" "unprognostic (1.87e-2)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (3.87e-1)" "unprognostic (1.21e-1)" "unprognostic (2.84e-1)" "unprognostic (1.19e-1)" 3.8 0.9 0.0 0.0 0.1 11.1 3.9 0.0 0.4 15.3 0.3 59.5 0.0 1.4 1.2 27.0 3.2 47.3 0.3 0.0 0.0 1.3 3.5 13.1 41.1 0.2 0.0 5.6 0.4 0.0 0.1 0.0 0.0 3.9 32.3 0.0 16.1 5.7 0.0 1.5 10.1 1.3 0.0 31.8 6.3 0.6 0.0 0.0 2.5 0.0 39.7 103.9 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 39.7 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 958.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV3-7 ENSG00000211938 "Immunoglobulin heavy variable 3-7" P01780 14 106062151-106062683 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 461.3;lymphoid tissue: 971.3" "Cell type enriched" "Detected in some" 255 "Plasma cells: 20463.1" "Cancer enhanced" "Detected in many" "stomach cancer: 18.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 147 "memory B-cell: 134.0;naive B-cell: 107.0" "Lineage enriched" "Detected in single" 163 "B-cells: 134.0" "Cell line enhanced" "Detected in some" "Daudi: 7.6;HL-60: 3.1;K-562: 3.0;NB-4: 3.0;RPMI-8226: 5.8;SH-SY5Y: 4.8;TIME: 2.9" "Immunoglobulin genes" NA NA 39000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.29e-2)" "unprognostic (5.57e-3)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-6)" "unprognostic (1.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (5.18e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (7.70e-2)" 47.8 10.1 0.7 50.1 1.0 71.1 202.7 0.3 0.8 87.4 0.6 461.3 154.1 37.7 8.2 17.8 13.4 37.0 2.2 0.2 0.4 17.6 20.3 56.4 102.5 1.6 2.8 24.7 4.8 2.9 1.8 0.3 2.3 9.2 303.5 0.0 265.5 22.9 1.3 9.6 206.0 3.6 3.9 610.4 230.4 13.2 0.4 0.0 21.1 0.1 971.3 42.9 14.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.0 0.0 0.0 3.0 0.5 0.0 0.0 0.4 2.6 5.8 0.0 0.0 2.3 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.7 0.0 1.2 1.6 0.0 0.1 0.0 0.6 0.0 0.4 0.8 0.2 0.1 0.0 0.2 134.0 0.2 0.2 0.3 107.0 0.1 0.1 0.1 0.1 0.2 0.6 0.2 12.6 0.7 1.0 0.3 0.8 0.2 0.4 1.6 2.8 2.3 3.9 0.4 1.3 0.0 0.0 0.0 0.0 80.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.5 0.0 5.3 0.0 0.0 0.0 4.4 31.1 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20463.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 7.4 0.0 0.5 0.0 IGHV3-72 ENSG00000225698 "Immunoglobulin heavy variable 3-72" A0A0B4J1Y9 14 106790691-106791233 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 75.7;lymphoid tissue: 121.6;urinary bladder: 101.3" "Cell type enriched" "Detected in some" 271 "Plasma cells: 3507.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "memory B-cell: 52.4" "Lineage enriched" "Detected in many" 50 "B-cells: 52.4" "Cell line enhanced" "Detected in some" "NB-4: 1.3;RH-30: 1.3;RPMI-8226: 1.2;TIME: 2.2;U-698: 5.8" "Immunoglobulin genes" NA NA 9600000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.10e-6)" "unprognostic (2.18e-2)" "unprognostic (1.32e-2)" "unprognostic (2.93e-2)" "prognostic favorable (8.57e-5)" "unprognostic (9.14e-3)" "unprognostic (3.98e-2)" "unprognostic (1.86e-1)" "unprognostic (9.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.27e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (9.29e-2)" "unprognostic (1.29e-1)" "unprognostic (8.81e-2)" "unprognostic (1.32e-1)" 4.8 2.6 0.1 18.4 0.1 15.5 7.0 0.0 0.6 5.2 0.1 75.7 28.4 3.0 2.9 17.4 3.4 0.3 0.3 0.0 0.0 1.9 5.3 8.6 2.7 0.5 0.0 2.3 3.4 0.1 0.2 0.1 0.1 1.9 47.6 0.0 46.6 0.9 0.1 0.3 58.2 5.4 0.1 121.6 29.4 0.0 0.0 2.6 2.2 0.5 12.1 101.3 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 1.3 0.2 0.0 0.0 0.1 1.3 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.2 0.1 0.0 0.3 0.0 5.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 52.4 0.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.1 0.1 0.0 0.6 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.1 7.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3507.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 IGHV3-73 ENSG00000211976 "Immunoglobulin heavy variable 3-73" A0A0B4J1V6 14 106802694-106803233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 141.8;lymphoid tissue: 83.0;urinary bladder: 81.7" "Cell type enhanced" "Detected in some" "B-cells: 6.1;Cholangiocytes: 1.5;Erythroid cells: 5.3;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 86 "memory B-cell: 69.9;naive B-cell: 42.9" "Lineage enriched" "Detected in single" 107 "B-cells: 69.9" "Cell line enhanced" "Detected in some" "Daudi: 1.4;HEL: 1.1;HL-60: 1.1;K-562: 1.7" "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 57: B-cells - Immune response" "prognostic favorable (7.89e-4)" "unprognostic (3.61e-2)" "unprognostic (1.55e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.25e-7)" "unprognostic (4.23e-2)" "unprognostic (4.32e-2)" "unprognostic (5.40e-1)" "unprognostic (1.57e-2)" "unprognostic (2.27e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.45e-1)" "unprognostic (2.52e-1)" "unprognostic (5.25e-2)" "unprognostic (4.37e-2)" 4.4 13.3 0.0 9.4 0.0 15.8 10.5 0.0 0.5 4.7 0.3 76.9 141.8 5.1 0.0 4.0 3.9 19.1 10.4 0.0 0.0 3.0 9.8 12.3 0.0 0.1 0.0 1.5 5.9 0.0 0.5 0.1 0.2 4.3 58.0 0.0 30.6 3.9 0.4 0.2 23.6 0.4 0.1 83.0 47.5 0.4 0.0 0.0 4.1 0.0 0.2 81.7 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 69.9 0.1 0.0 0.0 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 IGHV3-74 ENSG00000224650 "Immunoglobulin heavy variable 3-74" A0A0B4J1X5 14 106810442-106811131 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.9;lymphoid tissue: 327.0;salivary gland: 102.6" "Cell type enriched" "Detected in some" 454 "Plasma cells: 19404.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 861 "Daudi: 2948.0" "Immunoglobulin genes" NA NA 27000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.47e-4)" "unprognostic (9.70e-2)" "prognostic favorable (8.33e-4)" "unprognostic (6.96e-3)" "unprognostic (1.42e-1)" "prognostic favorable (7.79e-4)" "unprognostic (1.06e-1)" "unprognostic (7.06e-2)" "unprognostic (3.94e-1)" "unprognostic (3.07e-2)" "unprognostic (2.42e-1)" "unprognostic (9.85e-2)" "prognostic unfavorable (4.70e-6)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" 11.3 1.2 0.1 0.0 0.2 0.0 12.6 0.0 1.5 9.3 0.0 103.9 0.0 2.1 1.9 87.3 2.6 1.3 0.7 0.0 0.3 4.7 6.6 22.2 0.0 0.6 0.0 2.5 1.9 0.6 0.8 0.1 0.2 6.5 0.0 0.0 102.6 0.0 0.5 3.2 74.1 0.0 0.3 327.0 27.5 0.2 0.1 0.0 7.7 0.0 0.0 46.4 5.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 2948.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.1 1.1 0.2 0.0 0.0 0.1 1.2 0.0 0.1 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.7 0.3 0.4 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.5 0.0 0.3 0.6 0.0 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.0 42.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 1.4 27.5 0.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 19404.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 2.3 0.0 0.1 0.3 IGHV3OR15-7 IGHV3/OR15-7 ENSG00000259490 "Immunoglobulin heavy variable 3/OR15-7 (pseudogene)" 15 19987656-19988117 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 2.0;stomach 1: 1.8" "Cell type enriched" "Detected in single" 104 "Plasma cells: 10.4" "Cancer enhanced" "Detected in many" "lung cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.08e-2)" "unprognostic (8.21e-2)" "unprognostic (1.08e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.43e-5)" "unprognostic (4.56e-1)" "unprognostic (3.12e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-4)" "unprognostic (7.46e-2)" "unprognostic (1.35e-1)" "unprognostic (3.50e-1)" "unprognostic (1.24e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-10 IGHV3/OR16-10 ENSG00000233732 "Immunoglobulin heavy variable 3/OR16-10 (non-functional)" 16 32995048-32995505 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 4.8;intestine: 6.3;lymphoid tissue: 8.3;salivary gland: 7.0;stomach 1: 5.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.1" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.40e-3)" "unprognostic (4.22e-2)" "unprognostic (3.45e-2)" "unprognostic (3.41e-4)" "unprognostic (2.20e-1)" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" "unprognostic (2.30e-1)" 0.0 0.2 0.0 1.0 0.0 1.1 0.7 0.2 0.3 0.0 0.0 4.1 6.2 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.3 0.0 7.0 0.0 0.0 0.0 2.1 1.1 0.1 1.4 5.6 3.5 0.1 0.9 0.2 0.0 8.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.5 0.4 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-12 IGHV3/OR16-12 ENSG00000270467 "Immunoglobulin heavy variable 3/OR16-12 (non-functional)" 16 33802764-33803217 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 13.7;lymphoid tissue: 20.3;stomach 1: 9.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "memory B-cell: 4.5" "Lineage enriched" "Detected in single" 46 "B-cells: 4.5" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (2.04e-1)" "unprognostic (2.54e-1)" "unprognostic (1.44e-3)" "unprognostic (1.07e-1)" "unprognostic (7.10e-2)" "unprognostic (5.02e-1)" "unprognostic (1.29e-1)" 0.0 0.0 0.0 7.7 0.0 1.0 3.3 0.0 0.0 1.2 0.0 8.3 13.7 0.0 0.0 1.1 0.1 1.6 0.0 0.0 0.0 0.1 0.3 1.3 1.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 4.1 0.0 2.5 0.0 0.0 0.0 3.6 0.0 0.0 2.1 9.8 0.2 0.0 1.0 0.0 0.0 20.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-13 IGHV3/OR16-13 ENSG00000271178 "Immunoglobulin heavy variable 3/OR16-13 (non-functional)" 16 33827214-33827661 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 32.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "stomach cancer: 4.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 28 "memory B-cell: 18.1" "Lineage enriched" "Detected in single" 181 "B-cells: 18.1" "Cell line enriched" "Detected in some" 818 "Daudi: 1604.0" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (7.59e-4)" "unprognostic (4.14e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.23e-5)" "unprognostic (1.34e-1)" "unprognostic (2.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "unprognostic (3.26e-5)" "unprognostic (6.83e-2)" "unprognostic (1.71e-1)" "unprognostic (3.09e-1)" "unprognostic (3.04e-1)" 0.2 0.0 0.1 5.3 0.0 0.6 0.4 0.0 0.1 1.3 0.0 6.7 6.0 0.0 0.0 0.3 0.2 0.4 0.0 0.0 0.0 0.2 0.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.9 0.0 7.0 0.0 0.0 0.0 4.0 0.1 0.0 32.2 4.2 0.0 0.0 1.0 0.3 0.0 10.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1604.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-17 IGHV3/OR16-17 ENSG00000259680 "Immunoglobulin heavy variable 3/OR16-17 (non-functional)" 16 33844784-33845229 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 11.5;lymphoid tissue: 24.4;stomach 1: 11.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "memory B-cell: 1.5;naive B-cell: 2.5" "Lineage enriched" "Detected in single" 26 "B-cells: 2.5" "Not detected" "Not detected" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.57e-3)" "unprognostic (1.35e-2)" "unprognostic (5.32e-2)" "prognostic favorable (6.96e-5)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "unprognostic (2.03e-3)" "unprognostic (7.52e-2)" "unprognostic (1.00e-1)" "unprognostic (2.18e-1)" "unprognostic (3.58e-1)" 0.2 0.1 0.0 9.3 0.0 4.3 3.3 0.0 0.0 4.0 0.0 11.5 9.6 0.1 0.0 4.0 0.1 0.5 1.0 0.0 0.0 0.0 0.4 1.0 1.3 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 6.4 0.0 4.3 0.0 0.0 0.0 5.6 0.4 0.0 4.1 11.8 0.0 0.0 0.5 0.0 0.0 24.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-8 IGHV3/OR16-8 ENSG00000271130 "Immunoglobulin heavy variable 3/OR16-8 (non-functional)" 16 33009175-33009620 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 32.0;lymphoid tissue: 49.4;stomach 1: 32.9;urinary bladder: 40.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "memory B-cell: 7.3" "Lineage enriched" "Detected in single" 74 "B-cells: 7.3" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (2.58e-4)" "unprognostic (3.25e-2)" "unprognostic (9.53e-3)" "unprognostic (1.56e-1)" "unprognostic (2.43e-4)" "unprognostic (1.31e-1)" "unprognostic (4.47e-1)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (2.60e-7)" "unprognostic (2.24e-2)" "unprognostic (4.11e-1)" "unprognostic (1.41e-1)" "unprognostic (9.16e-2)" 2.3 0.8 0.0 13.8 0.0 5.9 4.5 0.0 0.0 2.7 0.0 30.1 32.0 0.2 0.0 1.9 0.7 5.3 0.0 0.0 0.0 0.1 0.9 3.2 3.6 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 14.8 0.0 10.0 0.0 0.0 0.0 9.0 1.8 0.0 5.8 32.9 0.1 0.0 3.0 0.7 0.0 49.4 40.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV4-28 ENSG00000211952 "Immunoglobulin heavy variable 4-28" A0A0C4DH34 14 106324254-106324760 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 44.8;lymphoid tissue: 87.4;salivary gland: 39.9;stomach 1: 30.7;urinary bladder: 122.6" "Cell type enriched" "Detected in some" 230 "Plasma cells: 346.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "spinal cord: 1.3" "Group enriched" "Detected in some" 206 "memory B-cell: 28.7;naive B-cell: 12.5" "Lineage enriched" "Detected in single" 288 "B-cells: 28.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.14e-3)" "unprognostic (1.32e-2)" "unprognostic (8.05e-2)" "unprognostic (6.64e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.58e-2)" "unprognostic (7.52e-2)" "unprognostic (1.03e-1)" "unprognostic (5.74e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" 1.8 11.3 0.0 40.9 0.0 6.0 12.9 0.0 0.2 3.3 0.1 44.8 44.8 1.0 0.0 12.5 1.9 7.7 1.2 0.0 0.0 1.8 2.4 8.9 10.0 0.0 0.0 3.5 0.4 0.0 0.2 0.0 0.0 0.8 44.1 0.0 39.9 1.7 0.0 0.5 30.2 2.0 1.3 42.3 30.7 0.5 0.0 5.8 4.3 0.0 87.4 122.6 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV4-31 ENSG00000231475 "Immunoglobulin heavy variable 4-31" A0A087WSY4 14 106349283-106349792 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 467.7;urinary bladder: 190.8" "Cell type enriched" "Detected in some" 183 "Plasma cells: 1651.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "spinal cord: 1.6" "Group enriched" "Detected in some" 48 "memory B-cell: 43.6;naive B-cell: 19.4" "Lineage enriched" "Detected in single" 66 "B-cells: 43.6" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.4;SH-SY5Y: 1.0" "Immunoglobulin genes" NA NA 710000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.53e-3)" "unprognostic (9.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.74e-4)" "prognostic favorable (4.64e-5)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (5.05e-2)" "unprognostic (1.72e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (2.00e-1)" "unprognostic (1.48e-1)" "unprognostic (3.63e-1)" "unprognostic (1.09e-1)" 4.3 1.7 0.0 48.0 0.0 5.4 37.6 0.0 0.3 15.4 0.0 103.8 72.1 6.5 1.5 32.2 5.3 105.2 11.7 0.0 0.7 3.9 6.3 19.1 104.0 0.2 0.2 58.0 4.7 0.2 0.5 0.0 0.1 11.4 24.9 0.0 53.2 8.4 0.1 1.3 90.4 3.1 1.6 138.6 87.8 1.3 0.2 76.0 15.7 0.0 467.7 190.8 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 0.1 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.7 0.2 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1651.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 283.3;urinary bladder: 278.5" "Cell type enriched" "Detected in some" 197 "Plasma cells: 15696.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 602 "U-698: 5353.4" "Immunoglobulin genes" NA NA 4300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (5.34e-3)" "unprognostic (6.12e-2)" "prognostic favorable (2.77e-4)" "unprognostic (8.06e-2)" "unprognostic (3.89e-1)" "unprognostic (1.23e-1)" "unprognostic (4.27e-2)" "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (7.51e-2)" 7.9 3.0 0.0 0.0 0.3 0.0 9.8 0.1 1.5 12.0 0.1 83.5 0.0 5.5 0.9 7.3 22.5 0.0 2.3 0.0 0.2 7.2 7.0 33.4 0.0 0.6 0.2 22.0 1.3 0.4 0.9 0.3 0.3 3.8 2.2 0.0 82.1 0.0 0.3 2.8 54.2 0.3 0.1 283.3 48.0 0.3 0.1 0.0 19.3 0.0 0.0 278.5 4.0 1.4 3.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.5 2.6 3.2 0.0 0.0 1.4 0.0 4.1 0.0 0.3 0.0 0.6 3.7 0.0 0.1 8.8 0.4 1.8 0.0 0.8 5353.4 0.0 3.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.1 0.5 0.0 0.8 0.0 0.3 0.1 1.5 0.0 0.2 0.6 0.2 0.3 0.1 0.1 1.4 0.0 0.0 0.0 0.0 79.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15696.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.6 0.0 0.0 0.0 IGHV4-39 ENSG00000211959 "Immunoglobulin heavy variable 4-39" P01824 14 106421711-106422218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 251.6;lymphoid tissue: 474.9;salivary gland: 247.1;urinary bladder: 541.3" "Cell type enriched" "Detected in some" 432 "Plasma cells: 48104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.6;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Daudi: 1.8;HL-60: 2.4;NB-4: 2.2;RH-30: 2.1;RPMI-8226: 1.4;U-266/70: 2.1;U-698: 2.0" "Immunoglobulin genes" NA NA 5000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.18e-3)" "unprognostic (2.99e-3)" "unprognostic (5.95e-3)" "unprognostic (1.46e-2)" "unprognostic (5.65e-2)" "unprognostic (2.38e-3)" "unprognostic (4.48e-2)" "unprognostic (2.63e-1)" "unprognostic (1.77e-1)" "unprognostic (2.23e-2)" "unprognostic (2.35e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (2.04e-2)" "unprognostic (2.77e-1)" "unprognostic (7.68e-2)" "unprognostic (8.33e-2)" 17.8 6.5 0.5 378.0 0.5 14.5 33.2 0.1 0.8 24.0 1.5 251.6 4.4 12.5 2.5 19.1 17.7 0.0 11.4 0.1 0.2 13.8 13.8 54.9 0.0 0.8 1.2 17.6 3.7 1.2 1.4 0.0 0.6 7.1 5.0 0.0 247.1 9.5 0.5 12.1 143.6 2.0 0.1 474.9 108.1 1.3 0.4 2.8 37.2 0.0 5.3 541.3 13.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 1.1 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.2 0.2 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.2 1.6 0.1 0.1 0.1 1.7 0.5 0.1 1.1 0.1 0.1 0.2 0.1 0.0 0.5 0.5 0.1 0.8 0.1 0.2 0.8 1.2 0.6 0.1 0.4 0.3 0.0 0.0 0.0 0.0 89.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 111.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48104.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.3 0.0 IGHV4-4 ENSG00000276775 "Immunoglobulin heavy variable 4-4" A0A075B6R2 14 106011922-106012420 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 567.7;urinary bladder: 768.4" "Cell type enriched" "Detected in some" 285 "Plasma cells: 2624.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 10 "midbrain: 4.8" "Group enriched" "Detected in some" 23 "memory B-cell: 56.6;naive B-cell: 31.2" "Lineage enriched" "Detected in many" 30 "B-cells: 56.6" "Cell line enriched" "Detected in some" 18 "Karpas-707: 34.5" "Immunoglobulin genes" NA NA 3800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.60e-6)" "unprognostic (2.24e-1)" "unprognostic (6.27e-2)" "unprognostic (1.30e-1)" "unprognostic (2.10e-1)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (3.16e-1)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.05e-1)" 9.4 2.5 0.0 131.4 0.0 17.8 63.6 0.0 0.2 37.5 0.1 205.2 159.9 3.8 0.8 59.8 53.4 104.9 0.9 0.0 0.1 5.5 6.6 36.9 173.2 0.3 4.8 10.0 6.0 0.4 0.4 0.0 0.1 4.0 140.2 0.0 78.2 15.0 0.3 3.8 78.6 13.4 0.4 186.4 175.0 1.6 0.1 31.8 16.7 0.0 567.7 768.4 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 34.5 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 56.6 0.2 0.2 0.0 31.2 0.6 0.0 0.0 0.0 0.0 1.9 0.6 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.3 4.8 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2624.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-59 ENSG00000224373 "Immunoglobulin heavy variable 4-59" P01825 14 106627249-106627825 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 525.9;lymphoid tissue: 911.2;urinary bladder: 702.5" "Cell type enriched" "Detected in some" 301 "Plasma cells: 12374.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 2.0" "Group enriched" "Detected in some" 37 "memory B-cell: 169.0;naive B-cell: 77.2" "Lineage enriched" "Detected in many" 51 "B-cells: 169.0" "Cell line enhanced" "Detected in some" "MOLT-4: 8.1;SCLC-21H: 2.0;SH-SY5Y: 4.2" "Immunoglobulin genes" NA NA 5500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.62e-5)" "unprognostic (3.95e-2)" "unprognostic (7.25e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-2)" "prognostic favorable (9.18e-5)" "unprognostic (2.88e-2)" "unprognostic (3.55e-1)" "unprognostic (2.16e-1)" "unprognostic (3.22e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.41e-7)" "unprognostic (6.04e-2)" "unprognostic (2.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.76e-1)" 23.9 3.2 0.0 260.5 0.3 95.5 89.3 0.0 1.1 40.4 0.8 525.9 301.0 12.1 2.7 89.6 17.9 168.0 27.9 0.0 0.6 13.8 20.6 89.9 148.0 0.3 0.1 23.5 10.3 1.7 1.5 0.3 0.2 12.6 456.0 0.0 225.7 8.8 0.5 3.6 222.6 19.5 2.0 465.3 260.5 15.0 0.2 86.4 44.1 0.0 911.2 702.5 10.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 8.1 1.0 0.3 0.3 0.0 0.8 1.0 0.7 0.0 0.0 2.0 4.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.4 0.4 0.1 1.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 169.0 0.0 0.2 1.4 77.2 0.1 0.0 0.0 0.0 0.1 3.3 0.1 11.9 0.0 0.3 0.0 1.1 0.0 0.6 0.3 0.1 0.2 2.0 0.2 0.3 0.0 0.0 0.6 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 11.2 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12374.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.6 0.0 0.5 0.0 IGHV4-61 ENSG00000211970 "Immunoglobulin heavy variable 4-61" A0A0C4DH41 14 106639119-106639657 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 206.7;lymphoid tissue: 385.2;stomach 1: 143.1" "Cell type enriched" "Detected in some" 98 "Plasma cells: 2432.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 25.5" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Cell line enriched" "Detected in single" 11 "MOLT-4: 8.7" "Immunoglobulin genes" NA NA 4400000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.11e-3)" "unprognostic (6.59e-2)" "unprognostic (4.92e-2)" "unprognostic (1.12e-2)" "prognostic favorable (3.71e-6)" "unprognostic (6.96e-2)" "unprognostic (5.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-2)" "unprognostic (9.95e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (3.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.24e-1)" "unprognostic (2.32e-2)" 6.4 44.4 0.0 97.5 0.1 30.8 56.0 0.0 0.2 10.1 0.1 206.7 185.7 5.8 0.0 15.5 5.0 22.4 3.1 0.0 0.1 5.5 10.5 28.2 54.4 0.3 0.1 10.4 1.3 0.2 0.7 0.0 0.3 4.1 121.8 0.0 104.3 7.0 0.2 0.7 86.5 8.0 0.3 181.3 143.1 0.9 0.0 30.1 23.0 0.0 385.2 43.9 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.0 0.0 8.7 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.1 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 4.6 0.0 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2432.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 IGHV4OR15-8 "IGHV4/OR15-8, IGHV4OR158, VSIG6" ENSG00000259261 "Immunoglobulin heavy variable 4/OR15-8 (non-functional)" 15 22184967-22185402 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.9;lymphoid tissue: 1.4;urinary bladder: 2.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "stomach cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.68e-3)" "unprognostic (9.63e-2)" "unprognostic (1.17e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.9 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.0 1.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV5-10-1 IGHV5-A ENSG00000282651 "Immunoglobulin heavy variable 5-10-1" A0A0J9YXX1 14 106107972-106108464 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 316.6;lymphoid tissue: 568.1" "Cell type enriched" "Detected in single" 36 "B-cells: 3.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "memory B-cell: 74.8;naive B-cell: 66.7" "Lineage enriched" "Detected in many" 16 "B-cells: 74.8" "Group enriched" "Detected in some" 6 "Daudi: 9.4;U-698: 4.8" HPA006014 Approved "Immunoglobulin genes" NA NA 1200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA006014: " 4.5 28.4 0.0 229.8 0.0 38.7 102.0 0.0 0.9 68.9 0.1 274.0 0.9 10.8 0.0 111.5 20.0 92.5 6.2 0.0 0.0 5.5 7.3 128.3 121.2 0.1 0.0 54.0 5.7 0.4 0.3 0.2 0.2 6.9 316.6 0.0 75.5 19.0 0.1 1.6 51.6 10.9 0.0 203.8 148.3 0.1 0.0 39.3 7.3 0.0 568.1 196.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.0 4.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 0.0 0.0 0.0 66.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV5-51 ENSG00000211966 "Immunoglobulin heavy variable 5-51" A0A0C4DH38 14 106578744-106579236 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 245.7;lymphoid tissue: 547.1;salivary gland: 224.5;urinary bladder: 353.3" "Cell type enriched" "Detected in some" 87 "Plasma cells: 5993.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.8;Daudi: 3.7;K-562: 2.4;NB-4: 1.7;TIME: 3.3" HPA006014 Approved "Immunoglobulin genes" NA NA 2700000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA006014: " "unprognostic (2.03e-3)" "unprognostic (1.00e-1)" "unprognostic (3.21e-2)" "unprognostic (7.65e-3)" "unprognostic (1.80e-2)" "prognostic favorable (5.47e-4)" "unprognostic (2.40e-2)" "unprognostic (1.15e-1)" "unprognostic (3.92e-2)" "unprognostic (6.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.70e-1)" "unprognostic (1.17e-1)" 20.0 4.8 0.3 0.0 0.0 0.0 25.9 0.1 1.7 17.8 0.7 245.7 0.0 8.6 6.3 19.1 15.2 27.1 2.1 0.1 0.7 15.4 15.0 56.2 0.0 0.9 0.0 8.8 17.1 1.0 2.2 0.6 0.2 11.2 0.0 0.0 224.5 0.0 0.7 3.2 144.8 1.7 0.6 547.1 99.9 4.8 0.1 0.0 25.6 0.0 0.0 353.3 14.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 1.3 1.2 0.8 0.0 0.1 0.0 0.7 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.7 0.1 0.7 0.9 0.0 0.2 0.6 0.1 1.3 0.0 0.0 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 44.9 0.0 0.0 0.0 0.7 1.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5993.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 441.3;lymphoid tissue: 159.0" "Cell type enriched" "Detected in some" 175 "Plasma cells: 2295.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 19.7" "Lineage enriched" "Detected in single" 53 "B-cells: 19.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 930000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-4)" "unprognostic (9.66e-2)" "unprognostic (4.55e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.85e-5)" "unprognostic (1.84e-1)" "unprognostic (2.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (3.69e-2)" "unprognostic (6.93e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" 13.0 2.1 0.3 0.0 0.1 0.0 7.5 0.0 0.4 4.2 0.2 441.3 0.0 1.2 0.0 17.9 4.3 1.5 2.7 0.0 0.1 3.2 6.2 13.6 0.0 0.3 0.1 0.9 11.5 0.0 0.3 0.0 0.1 1.6 0.0 0.0 56.7 8.6 0.1 2.0 40.9 11.2 0.3 159.0 19.5 0.3 0.2 0.0 6.8 0.0 0.0 3.7 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.1 19.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.1 0.3 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.1 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2295.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 IGHV7-4-1 ENSG00000282122 "Immunoglobulin heavy variable 7-4-1" A0A0J9YVY3 14 106025145-106025630 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.4;lymphoid tissue: 133.9" "Cell type enriched" "Detected in some" 4 "Plasma cells: 4.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 109 "memory B-cell: 8.3;naive B-cell: 13.5" "Lineage enriched" "Detected in single" 136 "B-cells: 13.5" "Cell line enriched" "Detected in some" 5 "Karpas-707: 5.4" "Immunoglobulin genes" NA NA 560000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" 3.9 2.9 0.3 58.3 0.0 39.0 21.1 0.0 0.6 7.7 0.2 60.8 8.3 0.5 0.0 4.7 0.8 3.1 0.8 0.0 0.0 2.1 2.8 49.1 7.5 0.0 0.0 0.9 0.7 0.0 0.2 0.0 0.0 2.6 97.4 0.0 42.2 8.7 0.3 0.2 42.9 0.2 0.1 68.5 24.2 0.2 0.0 45.6 5.9 0.0 133.9 10.4 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV7-81 ENSG00000211979 "Immunoglobulin heavy variable 7-81 (non-functional)" A0A0B4J1V7 14 106874583-106875071 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.7;lymphoid tissue: 18.3;stomach 1: 12.3" "Group enriched" "Detected in some" 12 "B-cells: 1.5;Plasma cells: 1.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 5.5;naive B-cell: 3.9" "Lineage enriched" "Detected in single" 14 "B-cells: 5.5" "Cell line enhanced" "Detected in some" "A549: 1.1;Daudi: 6.1;OE19: 1.2;U-698: 2.0" "Immunoglobulin genes" NA NA 270000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (5.71e-4)" "unprognostic (3.87e-1)" "unprognostic (1.06e-1)" "unprognostic (6.85e-2)" "unprognostic (2.67e-3)" "unprognostic (2.24e-1)" "unprognostic (2.07e-1)" "unprognostic (1.14e-2)" "unprognostic (6.16e-5)" "unprognostic (1.69e-3)" "unprognostic (1.78e-2)" "unprognostic (1.08e-1)" "unprognostic (5.63e-2)" "unprognostic (3.44e-1)" "unprognostic (3.63e-2)" 0.1 0.1 0.0 8.4 0.0 4.6 3.6 0.0 0.0 0.3 0.0 7.6 6.4 0.4 0.0 0.6 0.3 7.9 0.2 0.0 0.0 0.3 0.2 1.8 4.2 0.0 0.0 0.8 0.9 0.0 0.0 0.0 0.0 2.3 12.7 0.0 5.0 0.1 0.0 0.2 6.2 0.4 0.0 2.3 12.3 0.1 0.0 1.4 0.0 0.0 18.3 1.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.2 0.0 0.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.5 0.3 0.1 0.0 3.9 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGIP "C5orf53, LOC492311" ENSG00000182700 "IgA inducing protein" A6NJ69 5 140125937-140129392 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 55.4" "Cell type enhanced" "Detected in many" "Horizontal cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.7;ASC TERT1: 13.1" "Low region specificity" "Detected in all" "HPA041877, HPA048615" Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA041877: AB_2677721, HPA048615: AB_2680462" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" "unprognostic (2.00e-2)" "unprognostic (2.46e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (2.38e-1)" "unprognostic (5.05e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.94e-1)" "prognostic favorable (6.25e-6)" "unprognostic (2.93e-3)" "unprognostic (1.70e-1)" "unprognostic (5.98e-2)" "unprognostic (7.77e-2)" 8.3 8.9 43.6 2.9 41.0 0.1 7.7 38.9 55.4 12.7 29.7 14.1 3.7 9.2 9.0 6.3 8.9 3.7 11.8 38.3 40.9 9.3 10.0 9.4 4.5 41.5 43.8 9.9 8.4 13.7 18.6 4.2 43.9 12.0 3.8 19.5 8.0 8.1 10.4 9.0 8.3 4.6 45.7 7.8 9.2 4.0 45.1 4.2 11.9 9.2 3.9 10.7 11.6 40.8 2.0 0.6 0.9 2.8 13.7 13.1 1.3 5.1 5.0 1.1 1.5 2.0 1.6 3.8 5.3 6.9 0.6 2.1 1.1 3.1 2.3 3.4 1.9 0.8 3.0 1.5 3.2 1.0 1.3 4.5 7.7 2.2 4.2 8.6 1.4 2.8 0.6 1.5 4.4 1.8 1.2 2.6 0.2 1.6 1.5 1.2 2.4 1.7 6.6 1.8 1.0 1.5 2.8 1.8 3.1 1.0 1.4 3.0 8.8 3.5 0.3 1.2 2.8 3.6 2.5 1.3 3.7 2.6 2.6 0.0 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.2 0.0 43.6 41.0 38.9 55.4 38.3 40.9 41.5 43.8 43.9 45.7 45.1 40.8 6.5 12.8 5.1 14.0 2.3 2.0 2.1 3.2 0.0 21.3 4.5 3.7 14.4 8.6 5.4 3.7 14.6 2.5 1.4 5.5 0.0 3.3 1.9 2.4 3.5 5.4 9.0 0.0 22.2 1.8 1.5 4.4 3.6 2.2 8.2 3.0 7.9 5.9 1.0 28.6 19.8 4.2 0.0 2.2 1.3 1.3 6.5 2.2 7.2 14.0 3.9 5.9 3.1 9.5 17.6 2.8 4.4 17.0 1.3 3.7 7.8 4.2 6.1 8.8 0.0 11.2 5.5 2.4 1.3 1.7 4.0 1.8 1.9 2.8 4.0 2.2 IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 395.8;lymphoid tissue: 788.8" "Cell type enriched" "Detected in some" 92 "Plasma cells: 12442.9" "Cancer enhanced" "Detected in many" "stomach cancer: 17.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 259.8;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 1005 "B-cells: 259.8" "Cell line enhanced" "Detected in some" "BEWO: 1.5;Daudi: 2.1;RPMI-8226: 1.9;SH-SY5Y: 1.9" HPA048721 Approved "Immunoglobulin genes" NA NA 13000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (6.09e-4)" "prognostic favorable (1.59e-4)" "unprognostic (7.33e-2)" "unprognostic (3.74e-2)" "prognostic favorable (3.85e-5)" "unprognostic (5.89e-2)" "unprognostic (5.74e-1)" "unprognostic (7.13e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (6.59e-8)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.71e-1)" 13.6 144.8 0.0 201.7 0.2 73.1 116.8 0.0 0.4 50.8 0.2 395.8 240.6 7.3 0.0 57.1 16.2 69.6 9.9 0.1 0.1 13.7 17.8 65.3 238.6 0.6 0.0 18.1 7.2 0.2 1.4 0.0 1.1 7.2 278.6 0.0 219.0 5.4 0.4 2.8 231.2 11.2 1.2 360.5 254.9 6.7 0.0 69.5 32.7 0.0 788.8 243.3 9.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 259.8 0.0 0.1 0.1 164.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 24.3 0.0 0.2 0.0 0.4 0.1 0.1 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 1.8 1.6 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12442.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.3 5.0 0.0 0.0 0.0 IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 279.7;lymphoid tissue: 597.8;urinary bladder: 260.3" "Cell type enriched" "Detected in some" 559 "Plasma cells: 18463.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 523 "memory B-cell: 164.7;naive B-cell: 112.8" "Lineage enriched" "Detected in single" 621 "B-cells: 164.7" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 10000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.63e-4)" "unprognostic (7.81e-2)" "unprognostic (1.43e-3)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (8.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (3.84e-2)" "unprognostic (5.82e-2)" 11.8 4.7 0.1 159.1 0.1 40.0 75.9 0.0 0.8 76.0 0.6 279.7 199.4 6.3 0.5 34.3 6.6 99.0 11.4 0.0 0.1 9.2 14.9 40.5 155.0 0.2 0.0 17.7 2.0 0.1 3.6 0.1 0.1 5.6 235.6 0.0 126.9 30.9 0.8 0.7 143.6 11.8 0.1 315.4 158.9 2.0 0.1 45.7 18.4 0.0 597.8 260.3 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 164.7 0.0 0.0 0.1 112.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 16.9 0.1 0.1 0.0 0.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.6 21.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18463.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 375.0;lymphoid tissue: 454.4" "Cell type enriched" "Detected in some" 113 "Plasma cells: 4510.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 425 "memory B-cell: 105.7;naive B-cell: 82.2" "Lineage enriched" "Detected in single" 478 "B-cells: 105.7" "Cell line enhanced" "Detected in some" "Daudi: 1.9;K-562: 1.2;RPMI-8226: 2.0;SH-SY5Y: 1.4" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" 12.8 26.5 0.1 183.7 0.2 27.7 87.1 0.0 0.7 11.9 0.4 358.5 294.8 6.6 4.1 54.7 12.4 55.7 10.9 0.0 0.1 10.3 14.2 36.5 95.7 0.6 0.0 12.4 3.3 1.1 1.0 0.1 0.2 5.5 375.0 0.0 134.3 31.0 1.3 1.2 152.7 4.7 0.1 306.1 159.7 2.4 0.3 45.6 25.8 0.0 454.4 182.6 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.8 2.0 0.0 0.0 0.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 105.7 0.0 0.0 0.1 82.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 12.6 0.1 0.2 0.0 0.7 0.0 0.1 0.6 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4510.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 IGKV1-27 "A20, IGKV127" ENSG00000244575 "Immunoglobulin kappa variable 1-27" A0A075B6S5 2 89213423-89213928 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0;lymphoid tissue: 347.1;salivary gland: 177.6" "Cell type enriched" "Detected in some" 126 "Plasma cells: 4951.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 683 "memory B-cell: 152.7;naive B-cell: 185.3" "Lineage enriched" "Detected in single" 748 "B-cells: 185.3" "Cell line enhanced" "Detected in single" "BEWO: 1.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 8300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.56e-5)" "unprognostic (6.50e-3)" "unprognostic (2.65e-2)" "unprognostic (1.68e-3)" "unprognostic (1.72e-2)" "prognostic favorable (8.14e-4)" "unprognostic (9.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.41e-1)" "unprognostic (6.99e-3)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (8.84e-5)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-2)" 17.2 9.2 0.0 133.5 0.0 28.5 70.0 0.0 0.4 16.8 0.1 268.0 183.3 6.2 7.7 30.4 6.9 37.5 10.7 0.1 0.1 11.8 9.7 55.2 124.7 0.7 0.3 8.8 4.9 0.2 1.0 0.0 0.1 6.4 212.3 0.0 177.6 8.8 0.6 0.9 200.2 5.1 0.2 276.9 91.9 1.0 0.0 46.9 19.4 0.0 347.1 87.7 6.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 152.7 0.1 0.1 0.1 185.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 15.8 0.0 0.0 0.0 0.4 0.1 0.1 0.7 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 12.2 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4951.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89266494-89268506 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1727.5;stomach 1: 627.3;urinary bladder: 623.3" "Cell type enriched" "Detected in some" 131 "Plasma cells: 2044.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.5" "Region enriched" "Detected in many" 7 "spinal cord: 12.0" "Group enriched" "Detected in some" 378 "memory B-cell: 369.6;naive B-cell: 441.5" "Lineage enriched" "Detected in many" 411 "B-cells: 441.5" "Cell line enhanced" "Detected in some" "RPMI-8226: 2.7;SCLC-21H: 9.1;SH-SY5Y: 8.8;U-251 MG: 3.5" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-2)" "prognostic favorable (4.58e-5)" "unprognostic (5.06e-2)" "unprognostic (8.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.63e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-1)" 50.5 21.9 0.1 266.2 0.5 139.5 320.5 0.6 1.0 129.8 0.4 471.5 296.2 20.7 2.8 106.2 33.4 187.2 23.2 0.2 1.6 36.7 37.9 130.4 529.5 0.4 1.0 37.0 8.3 1.9 2.7 0.4 0.7 18.7 511.9 0.2 476.4 127.7 0.7 2.5 175.9 14.5 12.0 820.8 627.3 13.5 0.2 381.9 53.9 0.2 1727.5 623.3 26.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.1 1.9 2.7 0.0 0.0 9.1 8.8 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.4 3.5 0.7 0.0 0.2 0.0 0.6 0.0 0.4 0.3 0.4 0.1 0.0 0.1 369.6 0.2 0.1 0.3 441.5 0.2 0.1 1.0 0.2 0.3 0.3 0.2 39.5 0.1 0.5 0.6 1.0 0.2 1.6 0.4 1.0 0.7 12.0 0.2 1.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2044.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 IGKV1-37 "IGKV137, O14" ENSG00000239862 "Immunoglobulin kappa variable 1-37 (non-functional)" A0A075B6S9 2 89297264-89297785 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.2;lymphoid tissue: 17.2;urinary bladder: 5.6" "Cell type enriched" "Detected in some" 24 "Plasma cells: 73.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 247 "memory B-cell: 21.2;naive B-cell: 28.2" "Lineage enriched" "Detected in single" 283 "B-cells: 28.2" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" 0.1 0.2 0.0 2.9 0.0 0.8 2.4 0.0 0.0 0.5 0.0 4.5 3.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.4 1.2 2.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 2.6 0.6 0.0 0.0 2.0 0.2 0.0 3.7 1.5 0.0 0.0 0.9 0.1 0.0 17.2 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.5;lymphoid tissue: 254.9;salivary gland: 151.2;stomach 1: 83.2" "Cell type enriched" "Detected in some" 151 "Plasma cells: 16225.1" "Cancer enhanced" "Detected in many" "stomach cancer: 13.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 388 "memory B-cell: 1069.8;naive B-cell: 935.1" "Lineage enriched" "Detected in many" 415 "B-cells: 1069.8" "Cell line enriched" "Detected in some" 21 "Daudi: 194.2" HPA048721 Approved "Immunoglobulin genes" NA NA 8000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.76e-4)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "prognostic favorable (1.70e-5)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-6)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-1)" "unprognostic (2.25e-1)" 10.9 9.1 0.0 54.7 0.1 14.2 17.7 0.0 0.1 21.8 0.0 108.5 70.5 5.7 0.0 11.6 12.5 14.3 1.5 0.2 0.0 10.9 6.8 27.2 36.5 0.0 0.0 1.8 3.2 0.0 0.5 0.0 0.2 4.2 13.3 0.0 151.2 0.9 0.2 1.3 74.4 1.2 0.0 254.9 83.2 0.3 0.0 5.9 31.0 0.0 42.5 17.5 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 1.8 0.0 9.0 0.0 0.0 0.0 0.9 1.0 0.7 0.3 0.3 0.3 1069.8 0.5 0.4 1.1 935.1 0.3 0.6 2.5 0.4 0.6 1.3 0.8 136.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 10.7 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16225.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 4.9 0.0 0.3 0.0 IGKV1-5 ENSG00000243466 "Immunoglobulin kappa variable 1-5" P01602 2 88947301-88947957 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 777.1;lymphoid tissue: 1459.2;urinary bladder: 945.2" "Cell type enriched" "Detected in some" 240 "Plasma cells: 39194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 364 "memory B-cell: 859.0;naive B-cell: 860.5" "Lineage enriched" "Detected in many" 364 "B-cells: 860.5" "Cell line enhanced" "Detected in some" "Daudi: 4.0;HL-60: 2.4;RPMI-8226: 5.0;SCLC-21H: 2.9;SH-SY5Y: 4.5" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.19e-4)" "unprognostic (1.26e-2)" "unprognostic (3.12e-3)" "unprognostic (5.00e-3)" "unprognostic (1.59e-2)" "prognostic favorable (3.47e-4)" "unprognostic (7.60e-2)" "unprognostic (2.84e-1)" "unprognostic (1.68e-1)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (3.17e-2)" 35.8 82.0 0.2 639.7 0.2 115.4 233.9 0.1 1.6 115.8 0.6 777.1 528.7 17.1 2.0 146.2 86.9 124.8 18.7 0.1 0.5 36.2 32.0 125.3 387.2 1.0 0.2 60.8 10.8 0.5 3.0 0.4 0.3 16.7 745.0 0.0 392.2 34.8 0.9 3.2 429.7 24.4 1.3 915.4 456.3 11.5 0.2 155.3 58.4 0.0 1459.2 945.2 28.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.4 1.6 0.5 0.0 0.0 0.3 1.0 5.0 0.0 0.0 2.9 4.5 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.7 0.4 0.6 0.1 0.4 0.0 0.6 0.0 0.7 1.2 1.3 0.5 0.2 0.4 859.0 2.3 0.3 1.0 860.5 0.2 0.3 1.4 0.4 0.6 0.7 0.6 113.5 0.2 0.2 0.1 1.6 0.1 0.5 1.0 0.2 0.3 1.3 0.2 0.5 0.0 0.0 0.6 0.0 163.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 7.0 89.7 0.0 0.0 0.0 0.7 3.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39194.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 11.8 0.0 0.2 0.0 IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 155.5;lymphoid tissue: 606.3" "Cell type enriched" "Detected in some" 33 "Plasma cells: 877.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 801 "memory B-cell: 123.6;naive B-cell: 85.7" "Lineage enriched" "Detected in single" 946 "B-cells: 123.6" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.44e-5)" "unprognostic (5.25e-3)" "unprognostic (3.78e-2)" "unprognostic (8.68e-3)" "unprognostic (3.23e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.86e-3)" "unprognostic (3.86e-2)" "unprognostic (3.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (5.23e-3)" "unprognostic (3.02e-1)" "unprognostic (2.54e-1)" "unprognostic (2.54e-1)" 8.2 1.7 0.1 84.1 0.1 37.0 50.3 0.0 0.4 16.5 0.1 155.5 110.5 4.0 4.1 23.5 5.0 18.1 5.3 0.0 0.0 7.7 6.3 20.0 82.3 0.1 0.1 4.0 1.8 0.0 1.1 0.0 0.0 4.3 145.9 0.0 95.0 2.2 0.2 0.6 59.1 5.1 0.2 209.5 130.3 0.7 0.0 22.7 16.4 0.0 606.3 144.8 8.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 123.6 0.0 0.0 0.1 85.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.1 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 877.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 29.7;lymphoid tissue: 55.0;salivary gland: 21.2;stomach 1: 18.6;urinary bladder: 41.7" "Cell type enriched" "Detected in some" 40 "Plasma cells: 622.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 311 "memory B-cell: 131.0;naive B-cell: 136.4" "Lineage enriched" "Detected in single" 317 "B-cells: 136.4" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 6100000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.64e-4)" "unprognostic (1.56e-2)" "unprognostic (8.07e-2)" "unprognostic (6.41e-3)" "prognostic favorable (5.13e-4)" "unprognostic (6.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-2)" "unprognostic (1.75e-1)" "unprognostic (7.79e-2)" "prognostic unfavorable (4.14e-7)" "unprognostic (6.94e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-2)" "unprognostic (2.98e-1)" 2.1 2.5 0.0 13.5 0.0 7.1 6.7 0.0 0.1 2.0 0.0 29.7 12.0 1.3 0.0 2.9 1.4 5.4 1.5 0.0 0.0 3.3 2.1 4.8 13.7 0.0 0.0 0.5 0.9 0.0 0.1 0.0 0.0 1.4 19.3 0.0 21.2 0.7 0.0 0.1 13.9 0.6 0.0 51.3 18.6 0.3 0.0 7.0 3.3 0.0 55.0 41.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 131.0 0.0 0.4 0.1 136.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 622.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 IGKV1-9 "IGKV19, L8" ENSG00000241755 "Immunoglobulin kappa variable 1-9" A0A0C4DH69 2 89009982-89010515 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 428.1;lymphoid tissue: 671.3;stomach 1: 283.7" "Cell type enriched" "Detected in some" 116 "Plasma cells: 7178.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 705 "memory B-cell: 300.5;naive B-cell: 296.8" "Lineage enriched" "Detected in single" 709 "B-cells: 300.5" "Cell line enhanced" "Detected in some" "HL-60: 1.2;NB-4: 1.0;RPMI-8226: 2.9;TIME: 1.2" HPA048721 Approved "Immunoglobulin genes" NA NA 4500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.10e-7)" "unprognostic (1.30e-2)" "unprognostic (1.95e-2)" "unprognostic (2.55e-3)" "unprognostic (4.70e-2)" "prognostic favorable (4.91e-4)" "unprognostic (3.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.09e-2)" "unprognostic (6.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.04e-8)" "unprognostic (4.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (3.40e-1)" 12.6 12.6 0.2 184.3 0.4 53.6 202.8 0.0 1.3 15.8 0.4 428.1 267.0 8.3 0.8 52.9 78.3 30.0 13.9 0.1 0.1 15.4 17.9 40.1 201.8 0.3 0.1 20.7 2.5 0.5 1.3 0.1 0.2 12.8 348.6 0.0 221.3 13.3 0.5 1.6 182.8 13.3 0.4 313.1 283.7 35.1 0.1 85.1 34.2 0.0 671.3 187.5 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 1.0 0.3 0.0 0.0 0.0 0.9 2.9 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.5 0.0 0.2 0.0 0.2 0.0 0.2 0.4 0.1 0.2 0.0 0.1 300.5 0.1 0.0 0.3 296.8 0.0 0.1 0.3 0.2 0.2 0.1 0.3 34.5 0.2 0.4 0.0 1.3 0.1 0.1 0.3 0.1 0.2 0.4 0.1 0.3 0.0 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.0 0.0 0.0 1.8 0.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7178.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 IGKV1D-12 ENSG00000278857 "Immunoglobulin kappa variable 1D-12" P01611 2 90159840-90160335 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.6;lymphoid tissue: 47.5;salivary gland: 34.6" "Cell type enriched" "Detected in some" 178 "Plasma cells: 232.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "memory B-cell: 13.0;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 35 "B-cells: 13.0" "Cell line enhanced" "Detected in single" "RH-30: 2.2" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.94e-4)" "unprognostic (9.04e-4)" "unprognostic (3.42e-2)" "prognostic favorable (3.23e-4)" "unprognostic (3.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" 1.7 0.3 0.0 9.6 0.0 0.9 7.6 0.0 0.2 3.0 0.0 26.6 1.6 1.3 0.0 2.2 1.8 0.0 0.3 0.0 0.0 1.7 1.0 11.6 12.5 0.1 0.0 0.2 0.4 0.0 0.2 0.1 0.1 1.1 9.1 0.0 34.6 0.3 0.1 0.2 22.7 5.5 0.0 47.5 9.5 0.2 0.0 1.3 4.0 0.0 9.4 2.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.1 12.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-13 ENSG00000276566 "Immunoglobulin kappa variable 1D-13" "A0A0B4J2D9, P0DP09" 2 90154073-90154574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.7;lymphoid tissue: 317.6" "Cell type enriched" "Detected in some" 141 "Plasma cells: 6195.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 733 "memory B-cell: 480.8;naive B-cell: 331.6" "Lineage enriched" "Detected in single" 868 "B-cells: 480.8" "Cell line enhanced" "Detected in single" "Daudi: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 370000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (4.68e-6)" "unprognostic (4.10e-2)" "unprognostic (2.16e-1)" "unprognostic (5.71e-3)" "unprognostic (3.01e-3)" "unprognostic (1.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.84e-2)" "unprognostic (8.14e-2)" "unprognostic (2.50e-1)" "unprognostic (2.27e-1)" "unprognostic (4.68e-3)" "unprognostic (4.68e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.60e-2)" 4.8 0.4 0.0 101.2 0.0 34.8 34.3 0.0 0.0 46.6 0.0 85.6 21.7 5.4 0.0 17.9 10.2 2.5 3.5 0.0 0.0 8.1 6.4 39.4 317.6 0.0 0.0 1.0 1.9 0.0 0.4 0.0 0.1 3.1 78.3 0.0 54.2 1.4 0.0 1.1 103.7 6.8 0.0 102.8 20.3 2.7 0.0 29.0 7.2 0.0 223.2 45.9 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.4 0.3 0.1 0.1 0.2 480.8 0.2 0.1 0.5 331.6 0.0 0.0 0.4 0.1 0.1 0.2 0.1 42.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6195.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-16 ENSG00000241244 "Immunoglobulin kappa variable 1D-16" P01601 2 90100236-90100738 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 79.1;intestine: 92.0;lymphoid tissue: 165.5" "Cell type enriched" "Detected in some" 249 "Plasma cells: 1994.1" "Cancer enhanced" "Detected in many" "lung cancer: 17.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 327 "memory B-cell: 57.6;naive B-cell: 120.1" "Lineage enriched" "Detected in single" 442 "B-cells: 120.1" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 9000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.41e-4)" "unprognostic (4.41e-3)" "unprognostic (3.96e-3)" "unprognostic (5.39e-2)" "unprognostic (1.35e-3)" "unprognostic (8.61e-2)" "unprognostic (2.92e-1)" "unprognostic (1.27e-1)" "unprognostic (1.54e-2)" "unprognostic (6.61e-3)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (4.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.66e-2)" "unprognostic (2.84e-1)" 2.4 0.4 0.0 30.2 0.0 15.0 18.9 0.0 0.4 11.0 0.1 92.0 39.0 1.6 0.0 13.8 2.5 79.1 1.3 0.0 0.0 1.7 3.9 10.0 27.5 0.0 0.0 2.5 0.9 0.6 0.1 0.0 0.1 3.6 50.3 0.0 30.3 0.9 0.0 0.2 34.4 1.0 0.3 56.6 26.7 0.4 0.0 9.9 2.7 0.0 165.5 23.5 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 57.6 0.0 0.0 0.1 120.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1994.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGKV1D-17 ENSG00000242766 "Immunoglobulin kappa variable 1D-17" A0A075B6S4 2 90082635-90083291 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 6.8;lymphoid tissue: 12.5;salivary gland: 5.7" "Cell type enriched" "Detected in some" 13 "Plasma cells: 36.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 60 "memory B-cell: 7.7;naive B-cell: 4.1" "Lineage enriched" "Detected in single" 78 "B-cells: 7.7" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 1000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.47e-4)" "unprognostic (4.23e-2)" "unprognostic (2.43e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.68e-4)" "unprognostic (1.19e-1)" "unprognostic (6.18e-2)" "unprognostic (2.27e-1)" "unprognostic (8.86e-2)" "unprognostic (1.74e-5)" "unprognostic (1.38e-1)" "unprognostic (1.56e-2)" "unprognostic (1.17e-1)" "unprognostic (4.04e-3)" 1.3 0.1 0.1 5.1 0.1 0.9 0.8 0.1 0.2 0.3 0.8 6.8 1.5 0.2 0.0 0.5 0.8 0.6 0.0 0.1 0.1 0.3 0.4 1.5 0.8 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 2.2 0.0 5.7 0.3 0.0 0.4 4.7 0.4 0.1 12.5 2.0 0.0 0.1 0.3 0.5 0.0 4.5 1.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-33 ENSG00000239975 "Immunoglobulin kappa variable 1D-33" P01593 2 89913982-89916052 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;lymphoid tissue: 63.0;salivary gland: 73.3" "Cell type enriched" "Detected in some" 410 "Plasma cells: 5131.4" "Cancer enhanced" "Detected in many" "stomach cancer: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 116 "memory B-cell: 6.3;naive B-cell: 16.8" "Lineage enriched" "Detected in single" 169 "B-cells: 16.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 4900000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (5.10e-3)" "unprognostic (2.03e-1)" "unprognostic (2.11e-2)" "unprognostic (2.03e-4)" "unprognostic (7.90e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-2)" 2.8 0.5 0.0 3.8 0.1 2.3 8.3 0.0 0.1 3.6 0.1 32.7 1.3 1.4 0.0 4.6 2.7 2.6 0.2 0.2 0.2 4.0 2.2 17.9 6.8 0.0 0.2 0.4 0.5 0.0 0.1 0.0 0.0 1.6 2.0 0.0 73.3 8.6 0.0 0.5 19.1 0.0 0.5 63.0 21.2 0.1 0.0 4.7 3.3 0.2 9.1 16.8 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5131.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 IGKV1D-37 "IGKV1D37, O4" ENSG00000250036 "Immunoglobulin kappa variable 1D-37 (non-functional)" P0DSN7 2 89884740-89885216 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.7;stomach 1: 15.0;urinary bladder: 20.1" "Cell type enriched" "Detected in single" 11 "Plasma cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 209 "memory B-cell: 13.6;naive B-cell: 29.1" "Lineage enriched" "Detected in single" 284 "B-cells: 29.1" "Cell line enriched" "Detected in single" 5 "HDLM-2: 2.5" HPA048721 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (2.68e-1)" 0.1 0.0 0.0 4.2 0.0 3.3 2.4 0.0 0.0 0.8 0.0 8.6 12.7 0.1 0.4 2.1 0.2 0.5 0.2 0.4 0.0 0.1 0.4 0.8 4.1 0.0 0.1 0.4 1.2 0.0 0.0 0.1 0.0 0.7 1.0 0.0 7.1 0.0 0.2 0.0 6.0 0.2 0.0 6.5 15.0 0.2 0.0 1.1 0.1 0.0 2.5 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2922.1;lymphoid tissue: 6491.8;stomach 1: 2259.8" "Cell type enriched" "Detected in some" 298 "Plasma cells: 7890.2" "Cancer enhanced" "Detected in many" "stomach cancer: 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 226 "memory B-cell: 470.5;naive B-cell: 733.0" "Lineage enriched" "Detected in many" 275 "B-cells: 733.0" "Group enriched" "Detected in some" 36 "Daudi: 731.4;U-698: 516.7" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.88e-4)" "unprognostic (4.70e-2)" "unprognostic (2.14e-3)" "prognostic favorable (5.99e-5)" "unprognostic (3.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (2.96e-2)" "unprognostic (3.92e-1)" "unprognostic (1.84e-1)" 147.3 181.1 0.6 1609.8 0.8 466.1 990.4 0.5 4.2 369.0 2.1 2922.1 2055.2 80.0 52.5 611.3 132.1 629.8 87.5 0.4 2.0 82.3 171.8 685.1 1968.9 2.6 0.8 214.9 26.5 3.5 5.5 1.3 3.6 80.9 2261.1 0.4 1229.7 148.4 2.3 33.2 1255.9 88.7 4.2 1712.0 2259.8 27.6 1.3 770.5 209.3 0.0 6491.8 1816.1 46.9 2.5 0.3 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 731.4 0.5 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 5.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.3 6.6 2.4 0.0 0.0 1.0 2.9 10.3 0.0 0.0 11.1 17.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 2.5 0.0 0.1 516.7 0.0 1.6 0.0 0.5 0.4 0.8 0.6 0.2 0.4 470.5 0.3 0.3 0.4 733.0 0.5 0.2 2.6 0.8 0.4 0.4 0.3 47.6 0.6 0.8 0.5 4.2 0.4 2.0 2.6 0.8 3.6 4.2 1.3 2.5 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7890.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 14.0 0.0 0.0 0.0 IGKV1D-42 ENSG00000211633 "Immunoglobulin kappa variable 1D-42 (non-functional)" A0A075B6H8 2 90190193-90190681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.7;lymphoid tissue: 25.3" "Cell type enriched" "Detected in single" 93 "Plasma cells: 9.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 5.6;naive B-cell: 1.6" "Lineage enriched" "Detected in single" 57 "B-cells: 5.6" "Cell line enriched" "Detected in single" 5 "RPMI-8226: 2.6" HPA048721 Approved "Immunoglobulin genes" NA NA 41000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (8.08e-6)" "unprognostic (4.83e-2)" "unprognostic (2.22e-2)" "unprognostic (2.51e-3)" "unprognostic (1.84e-1)" "unprognostic (2.10e-2)" "unprognostic (1.66e-5)" "unprognostic (1.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (1.39e-1)" 0.1 0.0 0.0 7.6 0.0 6.6 10.8 0.0 0.0 0.8 0.0 18.8 7.5 0.2 0.3 1.4 0.2 1.7 0.1 0.0 0.0 0.0 0.3 2.8 2.6 0.1 0.0 4.1 1.1 0.0 0.0 0.0 0.0 0.1 47.7 0.0 8.5 0.0 0.0 0.1 7.9 0.0 0.0 4.2 13.9 0.0 0.0 0.6 0.3 0.0 25.3 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-43 ENSG00000242580 "Immunoglobulin kappa variable 1D-43" A0A0B4J1Z2 2 90209873-90210529 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.9;lymphoid tissue: 4.8;stomach 1: 3.6" "Cell type enriched" "Detected in some" 86 "Plasma cells: 695.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 152 "memory B-cell: 13.3;naive B-cell: 17.0" "Lineage enriched" "Detected in single" 171 "B-cells: 17.0" "Cell line enriched" "Detected in single" 310 "RPMI-8226: 79.1" HPA048721 Approved "Immunoglobulin genes" NA NA 380000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.32e-5)" "unprognostic (6.71e-2)" "unprognostic (4.01e-2)" "unprognostic (1.27e-2)" "unprognostic (4.57e-3)" "unprognostic (1.37e-3)" "unprognostic (3.15e-1)" "unprognostic (2.67e-2)" "unprognostic (3.82e-5)" "unprognostic (3.96e-2)" "unprognostic (2.20e-1)" "unprognostic (6.26e-2)" "unprognostic (1.06e-1)" 0.2 0.0 0.0 2.8 0.0 1.3 1.4 0.0 0.0 0.0 0.0 2.7 1.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 1.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 2.0 0.2 0.0 0.0 2.9 0.0 0.0 1.8 3.6 0.0 0.0 0.5 0.1 0.0 4.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 79.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 695.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV1D-8 ENSG00000239819 "Immunoglobulin kappa variable 1D-8" A0A087WSZ0 2 90220727-90221384 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 4.2;lymphoid tissue: 14.2;salivary gland: 5.6" "Cell type enriched" "Detected in some" 29 "Plasma cells: 338.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 323 "memory B-cell: 32.7;naive B-cell: 31.8" "Lineage enriched" "Detected in single" 328 "B-cells: 32.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 38.3" HPA048721 Approved "Immunoglobulin genes" NA NA 1900000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.93e-4)" "unprognostic (1.03e-3)" "unprognostic (2.23e-2)" "unprognostic (2.76e-3)" "prognostic favorable (8.80e-5)" "unprognostic (6.07e-2)" "unprognostic (9.76e-3)" "unprognostic (2.67e-1)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.35e-1)" "unprognostic (9.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" 0.5 0.0 0.0 5.3 0.0 0.7 1.2 0.0 0.0 0.6 0.0 4.2 1.6 0.1 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.3 0.3 1.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 2.6 0.0 5.6 0.0 0.0 0.0 2.8 0.0 0.0 8.3 1.9 0.0 0.0 1.2 0.6 0.0 14.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 338.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV1OR2-108 "IGKV1/OR2-108, IGKV1OR2108, IGO1" ENSG00000231292 "Immunoglobulin kappa variable 1/OR2-108 (non-functional)" 2 113406396-113406872 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.2;lymphoid tissue: 56.7" "Cell type enriched" "Detected in single" 652 "Plasma cells: 65.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "memory B-cell: 13.5;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 58 "B-cells: 13.5" "Cell line enhanced" "Detected in some" "Daudi: 6.6;HBEC3-KT: 7.2;hTEC/SVTERT24-B: 4.1;REH: 4.1" "Not detected" "Not detected" HPA048721 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.53e-6)" "unprognostic (2.73e-2)" "unprognostic (1.55e-2)" "unprognostic (3.37e-1)" "unprognostic (3.64e-3)" "unprognostic (3.57e-2)" "unprognostic (3.20e-1)" "unprognostic (5.21e-2)" "unprognostic (1.17e-1)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (9.96e-6)" "unprognostic (6.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.76e-1)" "unprognostic (1.95e-1)" 0.5 1.4 0.1 23.3 0.4 11.2 16.7 0.0 0.3 4.8 5.6 38.2 21.8 0.3 0.0 6.8 0.4 5.5 0.2 0.8 0.0 0.1 1.4 6.9 14.0 0.1 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.9 22.1 0.1 15.2 0.5 0.1 4.8 13.9 0.8 0.0 12.7 16.9 0.0 0.1 3.8 1.3 0.0 56.7 21.7 0.1 0.0 2.1 0.7 0.3 0.0 0.0 0.0 0.4 0.0 2.2 0.3 1.5 3.0 1.2 6.6 0.0 0.9 1.1 0.3 0.0 7.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 4.1 2.4 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.6 0.4 0.0 1.6 4.1 0.6 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.6 0.0 1.3 0.2 0.2 0.1 1.2 0.1 0.4 0.4 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 13.5 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.1 0.4 0.0 0.3 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2-24 ENSG00000241294 "Immunoglobulin kappa variable 2-24" A0A0C4DH68 2 89176328-89177160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 272.7;lymphoid tissue: 474.9;urinary bladder: 935.2" "Cell type enriched" "Detected in some" 252 "Plasma cells: 5620.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "memory B-cell: 48.1" "Lineage enriched" "Detected in single" 482 "B-cells: 48.1" "Cell line enhanced" "Detected in single" "NB-4: 1.3" "Immunoglobulin genes" NA NA 840000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.74e-6)" "unprognostic (4.92e-3)" "unprognostic (1.04e-2)" "unprognostic (2.38e-2)" "unprognostic (3.79e-3)" "prognostic favorable (1.59e-4)" "unprognostic (5.02e-2)" "unprognostic (1.65e-1)" "unprognostic (2.71e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.82e-5)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" 13.7 14.6 0.1 65.8 0.1 27.4 91.8 0.0 0.6 11.5 0.4 272.7 250.8 3.2 1.1 82.0 6.6 24.1 14.7 0.2 1.0 7.8 8.6 30.0 131.7 0.6 0.1 6.3 5.6 0.2 0.9 0.2 0.9 5.4 180.6 0.0 219.3 3.3 0.3 3.3 98.5 7.9 1.1 474.9 106.8 1.2 0.2 23.7 11.1 0.0 235.6 935.2 14.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.1 0.0 0.6 0.2 1.0 0.6 0.1 0.9 1.1 0.2 0.3 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5620.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGKV2-28 ENSG00000244116 "Immunoglobulin kappa variable 2-28" A0A075B6P5 2 89221698-89222461 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1044.6;lymphoid tissue: 1735.3" "Cell type enriched" "Detected in some" 92 "Plasma cells: 1868.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 11.1" "Lineage enriched" "Detected in single" 13 "B-cells: 11.1" "Cell line enhanced" "Detected in some" "BEWO: 2.4;Daudi: 2.8;HL-60: 3.6;K-562: 2.0;NB-4: 2.7;RPMI-8226: 4.5;SCLC-21H: 2.1;SH-SY5Y: 1.7" "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-2)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.12e-2)" "unprognostic (6.32e-3)" "unprognostic (3.14e-1)" "unprognostic (3.71e-2)" "unprognostic (5.21e-2)" "unprognostic (2.64e-2)" 36.2 40.2 0.2 402.4 0.2 180.2 425.2 0.1 1.1 56.6 0.9 1044.6 756.7 38.2 4.9 662.7 29.0 130.8 22.3 0.1 0.3 46.2 40.2 157.6 584.6 0.6 0.9 87.9 19.5 3.8 3.3 0.5 0.3 21.1 709.6 0.1 732.4 95.0 1.8 7.1 425.6 23.9 0.8 1207.7 530.0 161.9 0.2 167.6 84.8 0.0 1735.3 494.1 30.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 1.1 4.5 0.0 0.4 2.1 1.7 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.4 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.2 11.1 0.2 0.1 0.8 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.1 1.1 0.1 0.3 0.6 0.9 0.3 0.8 0.2 0.9 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1868.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 20.3 0.0 0.0 0.0 IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 631.0;lymphoid tissue: 670.2;stomach 1: 323.1" "Cell type enriched" "Detected in some" 365 "Plasma cells: 25365.6" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 316 "memory B-cell: 561.0;naive B-cell: 325.4" "Lineage enriched" "Detected in many" 400 "B-cells: 561.0" "Cell line enriched" "Detected in some" 388 "U-698: 8426.0" "Immunoglobulin genes" NA NA 6800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.84e-5)" "unprognostic (1.26e-2)" "unprognostic (2.88e-2)" "unprognostic (1.41e-1)" "prognostic favorable (6.78e-5)" "unprognostic (6.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-2)" "unprognostic (9.82e-3)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.53e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.50e-1)" 15.0 9.4 0.1 160.7 0.2 75.9 237.0 0.1 1.3 19.6 0.7 631.0 394.3 5.6 0.8 37.8 11.5 35.0 17.9 0.1 0.1 15.1 29.6 67.3 176.7 1.4 0.1 15.8 7.8 0.1 2.3 0.2 0.2 7.8 324.5 0.0 220.5 23.3 0.6 2.0 260.2 19.1 0.6 670.2 323.1 21.2 0.1 40.9 18.8 0.0 600.3 207.5 21.5 1.1 5.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 13.1 4.6 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.1 2.7 1.9 0.0 0.4 0.0 0.9 3.8 0.0 2.6 0.0 0.0 5.6 0.0 0.0 21.7 0.1 2.6 0.3 1.7 8426.0 0.0 2.7 0.0 0.5 0.4 0.2 0.2 0.0 0.2 561.0 0.1 0.2 0.4 325.4 0.0 0.2 1.4 0.2 0.3 0.7 0.3 53.3 0.1 0.2 0.1 1.3 0.1 0.1 1.4 0.1 0.2 0.6 0.1 1.1 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 30.5 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25365.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.2 0.0 0.3 0.0 IGKV2D-24 ENSG00000241566 "Immunoglobulin kappa variable 2D-24 (non-functional)" A0A075B6R9 2 90004797-90005629 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.7;lymphoid tissue: 25.5;urinary bladder: 15.3" "Cell type enriched" "Detected in single" 207 "Plasma cells: 165.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hippocampal formation: 1.8" "Group enriched" "Detected in some" 48 "memory B-cell: 6.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Cell line enriched" "Detected in single" 8 "U-937: 1.0" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.21e-4)" "unprognostic (1.78e-1)" "prognostic favorable (8.07e-4)" "unprognostic (2.09e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (4.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.74e-5)" "unprognostic (7.60e-2)" "unprognostic (1.57e-2)" "unprognostic (3.85e-1)" "unprognostic (3.47e-1)" 0.6 0.8 0.0 4.3 0.0 2.7 6.1 0.0 0.7 0.5 0.0 16.8 19.7 0.1 0.0 1.5 0.4 3.5 0.1 1.8 0.0 0.6 0.5 1.8 6.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 7.2 0.0 9.6 0.5 0.0 0.3 7.0 0.1 0.1 25.0 5.2 0.1 0.1 1.7 0.4 0.0 25.5 15.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 165.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-26 ENSG00000211623 "Immunoglobulin kappa variable 2D-26" A0A0A0MRZ7 2 89985922-89986702 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 245 "memory B-cell: 21.8;naive B-cell: 27.1" "Lineage enriched" "Detected in single" 272 "B-cells: 27.1" "Cell line enriched" "Detected in single" 10 "U-698: 1.0" "Immunoglobulin genes" NA NA 1000000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.11e-1)" "unprognostic (6.09e-2)" 0.0 0.4 0.0 1.5 0.1 0.5 1.0 0.0 0.2 0.1 0.0 4.6 3.5 0.0 0.0 0.6 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.2 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 0.0 0.0 2.8 0.0 0.0 2.3 1.3 0.0 0.0 0.5 0.0 0.0 6.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-28 ENSG00000242534 "Immunoglobulin kappa variable 2D-28" P01615 2 89959979-89960754 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 221.6;lymphoid tissue: 462.7;salivary gland: 259.7" "Cell type enriched" "Detected in some" 98 "Plasma cells: 4332.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 224 "memory B-cell: 3054.0;naive B-cell: 2203.9" "Lineage enriched" "Detected in all" 260 "B-cells: 3054.0" "Cell line enhanced" "Detected in some" "HDLM-2: 5.0;RPMI-8226: 2.0;SCLC-21H: 1.9;SH-SY5Y: 4.3;U-698: 4.4" "Immunoglobulin genes" NA NA 3500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.88e-3)" "unprognostic (2.68e-2)" "unprognostic (2.51e-3)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (4.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-1)" 9.9 4.8 0.1 162.1 0.2 23.3 35.2 0.0 1.5 7.6 0.3 203.7 221.6 8.3 1.2 113.5 14.0 26.1 4.8 0.3 0.4 11.5 13.3 40.6 166.6 0.7 0.2 2.8 1.9 0.1 0.9 0.4 0.4 11.1 65.9 0.0 259.7 19.2 0.3 1.4 143.3 8.7 0.2 462.7 186.4 5.7 0.2 40.9 37.8 0.3 192.0 157.9 8.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 1.1 0.0 0.0 0.0 5.0 0.0 1.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.4 0.1 0.0 0.0 0.7 0.0 2.0 0.0 0.0 1.9 4.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.6 1.3 0.0 4.4 0.0 1.1 0.0 11.7 7.8 1.2 1.2 0.5 1.3 3054.0 1.3 0.9 2.0 2203.9 0.2 0.9 2.2 1.0 1.5 1.4 1.3 248.7 0.1 0.2 0.0 1.5 0.3 0.4 0.7 0.2 0.4 0.2 0.2 0.3 0.0 0.0 0.0 0.0 44.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4332.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 31.5 0.0 0.1 0.0 IGKV2D-29 ENSG00000243264 "Immunoglobulin kappa variable 2D-29" A0A075B6S2 2 89947512-89948279 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 252.2;lymphoid tissue: 464.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 184.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 253 "memory B-cell: 360.5;naive B-cell: 489.4" "Lineage enriched" "Detected in many" 292 "B-cells: 489.4" "Cell line enhanced" "Detected in some" "Daudi: 8.5;HDLM-2: 1.2;TIME: 2.1;U-698: 2.2" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.31e-4)" "unprognostic (2.43e-2)" "unprognostic (1.34e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.34e-4)" "unprognostic (4.43e-3)" "unprognostic (1.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.47e-2)" "unprognostic (5.09e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (9.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.61e-1)" "unprognostic (7.80e-2)" 11.3 1.0 0.0 73.7 0.1 29.4 49.4 0.1 1.3 12.6 0.8 252.2 97.0 3.9 0.0 9.5 6.5 14.2 3.8 0.1 0.2 3.6 8.4 41.4 139.4 0.3 0.0 9.8 2.8 0.2 0.3 0.0 0.2 3.6 110.9 0.0 106.8 10.3 0.4 3.0 67.9 2.9 0.4 170.2 126.0 1.0 0.1 38.0 7.8 0.0 464.7 35.1 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.0 2.2 0.0 0.1 0.0 0.3 0.4 0.2 0.1 0.0 0.2 360.5 0.2 0.1 0.6 489.4 0.0 0.1 1.6 0.2 0.4 0.2 0.2 42.2 0.0 0.1 0.1 1.3 0.1 0.2 0.3 0.0 0.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 184.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 IGKV2D-30 ENSG00000239571 "Immunoglobulin kappa variable 2D-30" A0A075B6S6 2 89936859-89937679 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.3;lymphoid tissue: 33.5;stomach 1: 22.2" "Cell type enriched" "Detected in some" 222 "Plasma cells: 1314.8" "Cancer enhanced" "Detected in some" "stomach cancer: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 379 "memory B-cell: 124.9;naive B-cell: 164.0" "Lineage enriched" "Detected in single" 430 "B-cells: 164.0" "Cell line enriched" "Detected in some" 6 "U-698: 51.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (6.82e-2)" "unprognostic (1.58e-1)" "unprognostic (2.98e-4)" "unprognostic (5.74e-3)" "unprognostic (3.19e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.55e-1)" 0.4 0.4 0.0 6.4 0.0 4.3 5.9 0.0 0.1 0.8 0.0 15.3 11.8 0.4 0.0 1.0 0.4 0.8 0.8 0.1 0.1 1.4 0.7 2.8 6.7 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.1 0.5 11.2 0.0 13.0 4.6 0.0 1.2 8.5 2.0 0.0 29.3 22.2 0.1 0.0 1.6 0.8 0.0 33.5 5.6 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 51.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 124.9 0.0 0.1 0.1 164.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 19.3 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1314.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 IGKV3-11 ENSG00000241351 "Immunoglobulin kappa variable 3-11" P04433 2 89027171-89027731 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1373.3;lymphoid tissue: 2812.9;urinary bladder: 1822.6" "Cell type enriched" "Detected in some" 129 "Plasma cells: 27475.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 9 "spinal cord: 19.8" "Group enriched" "Detected in many" 292 "memory B-cell: 1729.8;naive B-cell: 1401.2" "Lineage enriched" "Detected in many" 323 "B-cells: 1729.8" "Cell line enhanced" "Detected in some" "BEWO: 3.0;Daudi: 2.0;SCLC-21H: 3.7;SH-SY5Y: 4.6" HPA047702 Approved "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (3.97e-3)" "unprognostic (1.17e-2)" "unprognostic (3.51e-2)" "unprognostic (1.91e-2)" "unprognostic (2.70e-2)" "prognostic favorable (1.36e-5)" "unprognostic (2.02e-1)" "unprognostic (3.20e-1)" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.26e-8)" "unprognostic (5.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" 45.8 60.5 0.4 733.2 0.3 189.1 385.3 0.2 2.1 136.2 0.6 1373.3 701.6 32.1 11.5 143.5 34.0 253.5 18.9 0.2 0.6 44.4 55.2 227.4 575.7 0.6 0.7 120.8 13.7 1.9 3.2 0.9 0.9 30.1 1090.9 0.1 496.0 60.9 1.2 14.2 536.0 59.5 19.8 1100.0 788.6 22.2 0.3 261.9 88.8 0.9 2812.9 1822.6 33.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.4 1.8 1.5 0.0 0.0 3.7 4.6 0.4 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.7 0.7 0.6 1.8 0.3 0.1 0.0 1.4 0.0 1.9 1.3 1.2 2.0 0.2 0.7 1729.8 0.8 0.6 1.6 1401.2 0.8 0.8 5.3 0.9 1.1 1.2 1.3 186.7 0.4 0.3 0.2 2.1 0.2 0.6 0.6 0.7 0.9 19.8 0.3 1.0 0.0 0.0 0.5 0.0 211.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 82.6 0.0 0.0 0.0 2.5 1.9 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.7 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27475.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 62.0 0.0 0.3 0.0 IGKV3-15 ENSG00000244437 "Immunoglobulin kappa variable 3-15" P01624 2 89085177-89085787 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 785.8;lymphoid tissue: 1996.3;urinary bladder: 784.8" "Cell type enriched" "Detected in some" 85 "Plasma cells: 22923.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 561 "memory B-cell: 2243.8;naive B-cell: 1651.4" "Lineage enriched" "Detected in all" 646 "B-cells: 2243.8" "Cell line enhanced" "Detected in some" "Daudi: 1.7;K-562: 1.3;NB-4: 1.9;RH-30: 1.2;RPMI-8226: 2.2;SCLC-21H: 1.4;SH-SY5Y: 2.5" HPA047702 Approved "Immunoglobulin genes" NA NA 7200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.57e-4)" "unprognostic (1.29e-2)" "unprognostic (7.02e-3)" "unprognostic (3.89e-3)" "unprognostic (9.06e-3)" "unprognostic (2.06e-3)" "unprognostic (5.36e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-1)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.15e-7)" "unprognostic (2.00e-1)" "unprognostic (2.54e-1)" "unprognostic (2.07e-1)" "unprognostic (1.17e-1)" 47.9 114.5 0.0 603.8 0.1 131.0 174.3 0.0 1.5 141.8 0.3 785.8 431.4 19.4 34.7 120.0 30.0 144.4 14.8 0.1 0.3 35.2 36.7 184.8 500.9 0.7 0.3 55.4 9.3 2.5 3.0 0.5 0.3 18.3 649.4 0.0 399.3 114.2 1.0 2.7 335.8 29.5 1.5 1020.7 629.8 64.8 0.2 250.2 77.7 0.0 1996.3 784.8 28.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.4 1.9 0.6 0.0 0.0 0.0 1.2 2.2 0.0 0.0 1.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.4 0.7 0.5 0.0 0.0 0.0 1.0 0.0 1.8 3.4 0.8 1.0 0.4 0.8 2243.8 1.0 1.1 1.8 1651.4 1.0 1.1 1.9 1.0 1.3 1.7 1.5 193.1 0.0 0.1 0.0 1.5 0.1 0.3 0.7 0.3 0.3 1.5 0.2 1.0 0.0 0.0 0.0 0.0 269.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.6 73.4 0.0 0.0 0.0 1.4 1.1 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 22923.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.5 0.0 0.0 0.2 0.0 0.0 28.2 0.0 0.0 0.0 IGKV3-20 ENSG00000239951 "Immunoglobulin kappa variable 3-20" P01619 2 89142574-89143160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3080.6;lymphoid tissue: 5246.5" "Cell type enriched" "Detected in some" 138 "Plasma cells: 52154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 329 "memory B-cell: 1602.7;naive B-cell: 1222.4" "Lineage enriched" "Detected in many" 373 "B-cells: 1602.7" "Group enriched" "Detected in many" 215 "U-266/70: 3769.9;U-266/84: 1732.3" HPA047702 Approved "Immunoglobulin genes" NA NA 20000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.86e-4)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-2)" "unprognostic (1.13e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.43e-1)" "unprognostic (3.43e-1)" "unprognostic (1.37e-1)" "unprognostic (3.93e-3)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (7.35e-2)" "unprognostic (5.08e-1)" "unprognostic (6.64e-2)" "unprognostic (2.70e-2)" 104.8 56.4 0.9 1791.2 0.9 380.3 736.4 0.5 4.2 326.9 2.6 3080.6 1714.2 59.0 7.8 302.1 105.2 637.2 55.7 0.5 1.6 106.2 113.5 454.0 2815.6 2.1 8.4 153.5 32.8 5.8 9.6 1.8 1.4 56.1 2731.8 0.2 1270.5 224.5 3.3 13.4 1355.8 82.8 10.4 2699.1 1412.9 24.7 1.2 671.5 224.3 1.8 5246.5 1644.0 70.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.5 0.0 2.1 0.0 0.0 0.0 6.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 2.0 5.9 2.8 0.0 0.0 3.0 6.0 10.4 0.0 0.0 7.7 12.8 1.4 0.0 0.1 0.0 0.0 0.8 4.4 0.0 2.0 1.5 4.3 3769.9 1732.3 1.8 0.0 2.3 0.0 4.0 1.2 0.7 0.7 0.4 0.8 1602.7 0.8 0.6 3.5 1222.4 0.4 0.7 4.2 0.8 1.0 0.9 0.8 196.9 0.9 0.9 0.5 4.2 0.5 1.6 2.1 8.4 1.4 10.4 1.2 1.5 0.1 3.2 1.3 0.0 376.9 0.0 0.0 0.0 5.2 0.0 0.1 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 9.4 0.0 0.0 0.0 55.3 124.4 0.0 1.3 0.0 3.6 5.0 0.1 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 52154.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.0 0.0 0.0 26.7 0.0 0.2 0.0 IGKV3-7 ENSG00000243063 "Immunoglobulin kappa variable 3-7 (non-functional)" A0A075B6H7 2 88978468-88979081 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;lymphoid tissue: 22.2;salivary gland: 15.9;stomach 1: 10.2" "Group enriched" "Detected in some" 37 "B-cells: 1.5;Plasma cells: 5.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 27.8;naive B-cell: 24.3" "Lineage enriched" "Detected in single" 65 "B-cells: 27.8" "Not detected" "Not detected" HPA047702 Approved "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.17e-4)" "unprognostic (3.07e-3)" "unprognostic (3.96e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-3)" "unprognostic (1.19e-1)" "unprognostic (5.91e-2)" "unprognostic (2.73e-1)" "unprognostic (4.24e-2)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" 0.3 0.4 0.0 15.0 0.0 4.2 3.9 0.0 0.0 2.1 0.0 18.6 15.1 0.3 0.1 1.5 0.1 1.3 0.0 0.0 0.0 0.2 0.5 1.8 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 13.6 0.0 15.9 0.1 0.0 0.0 11.2 0.7 0.0 4.9 10.2 0.0 0.0 1.4 0.1 0.0 22.2 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 24.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3D-11 ENSG00000211632 "Immunoglobulin kappa variable 3D-11" A0A0A0MRZ8 2 90172802-90173414 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 58.5;stomach 1: 27.7" "Cell type enriched" "Detected in some" 34 "Plasma cells: 196.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 468 "memory B-cell: 152.5;naive B-cell: 146.1" "Lineage enriched" "Detected in single" 478 "B-cells: 152.5" "Cell line enhanced" "Detected in single" "U-266/70: 2.1" HPA047702 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.40e-5)" "unprognostic (7.90e-3)" "unprognostic (1.91e-2)" "unprognostic (2.24e-3)" "prognostic favorable (5.58e-5)" "unprognostic (2.65e-2)" "unprognostic (2.13e-1)" "unprognostic (2.78e-1)" "unprognostic (6.31e-2)" "unprognostic (3.49e-1)" "unprognostic (3.61e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (1.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (1.24e-2)" 1.3 0.7 0.3 35.9 0.2 8.9 6.4 0.0 0.1 1.7 0.0 38.6 32.2 0.8 0.0 2.4 2.1 2.7 0.5 0.0 0.1 2.1 1.3 12.4 13.0 0.1 0.3 1.5 0.5 0.0 0.1 0.0 0.1 0.7 26.6 0.0 18.8 0.3 0.0 0.1 23.6 0.7 0.2 29.9 27.7 0.2 0.0 4.2 2.3 0.0 58.5 17.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 152.5 0.0 0.0 0.1 146.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 30.2 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 196.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 126.7;lymphoid tissue: 203.0;salivary gland: 54.1;stomach 1: 87.4;urinary bladder: 58.0" "Cell type enriched" "Detected in some" 622 "Plasma cells: 3673.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 191 "memory B-cell: 181.1;naive B-cell: 155.6" "Lineage enriched" "Detected in single" 206 "B-cells: 181.1" "Cell line enhanced" "Detected in some" "HaCaT: 1.0;HL-60: 2.6;SiHa: 1.7" HPA047702 Approved "Immunoglobulin genes" NA NA 4800000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.11e-4)" "prognostic favorable (7.46e-4)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (1.90e-3)" "unprognostic (7.20e-2)" "unprognostic (9.19e-2)" "unprognostic (4.93e-1)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (1.82e-6)" "unprognostic (8.99e-2)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" 3.1 4.4 0.1 93.5 0.4 11.1 17.1 0.1 0.5 5.9 0.3 111.6 63.0 1.0 0.0 16.4 5.2 10.1 2.3 0.1 0.2 3.6 2.0 18.0 43.6 0.4 0.2 17.9 4.0 0.3 0.1 0.0 0.2 1.7 126.7 0.0 54.1 1.1 0.1 0.6 46.7 4.3 0.3 56.3 87.4 0.2 0.1 13.0 4.5 0.0 203.0 58.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.6 0.0 0.6 0.0 0.1 0.8 0.0 0.0 0.0 0.0 181.1 0.0 0.0 0.1 155.6 0.0 0.0 0.0 0.1 0.1 0.0 0.1 27.5 0.1 0.4 0.1 0.5 0.1 0.2 0.4 0.2 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3673.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 131.8;lymphoid tissue: 275.4" "Cell type enriched" "Detected in some" 38 "Plasma cells: 289.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 1042 "memory B-cell: 197.3;naive B-cell: 99.0" "Lineage enriched" "Detected in single" 1388 "B-cells: 197.3" "Cell line enriched" "Detected in some" 4 "U-266/70: 19.5" HPA047702 Approved "Immunoglobulin genes" NA NA 11000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.82e-4)" "unprognostic (4.70e-3)" "unprognostic (3.16e-2)" "unprognostic (8.10e-3)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (3.37e-1)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.56e-6)" "unprognostic (7.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" 4.0 6.3 0.0 81.2 0.0 16.0 32.4 0.0 0.6 12.2 0.1 131.8 55.9 2.7 0.0 15.3 4.2 16.2 6.4 0.0 0.1 3.0 6.4 20.6 73.5 0.2 0.1 7.1 3.3 0.0 0.3 0.1 0.1 3.7 88.1 0.0 64.0 3.3 0.1 2.6 77.7 6.0 0.3 88.4 82.5 1.2 0.0 16.2 5.2 0.0 275.4 38.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.5 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 197.3 0.0 0.1 0.1 99.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.1 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 289.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 IGKV3D-7 ENSG00000228325 "Immunoglobulin kappa variable 3D-7" A0A0C4DH55 2 90234812-90235370 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 5.5;stomach 1: 4.4;urinary bladder: 5.5" "Cell type enriched" "Detected in single" 415 "Plasma cells: 207.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 2.8;naive B-cell: 4.3" "Lineage enriched" "Detected in single" 44 "B-cells: 4.3" "Cell line enriched" "Detected in some" 12 "RPMI-8226: 48.7" HPA047702 Approved "Immunoglobulin genes" NA NA 3700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (2.74e-1)" "unprognostic (8.62e-3)" "unprognostic (6.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.05e-1)" "unprognostic (4.02e-1)" 0.1 0.0 0.0 5.5 0.2 1.3 0.1 0.0 0.1 0.2 0.0 4.0 4.6 0.0 0.0 1.9 0.1 1.5 0.0 0.1 0.1 0.0 0.2 0.5 1.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 2.1 0.1 0.0 0.0 4.4 0.0 0.0 3.8 4.4 0.0 0.1 0.2 0.6 0.0 4.3 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3OR2-268 "IGKV268, IGKV3/OR2-268, IGKV3/OR2-268A, IGKV3OR2-268A" ENSG00000233999 "Immunoglobulin kappa variable 3/OR2-268 (non-functional)" 2 87338511-87339035 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 100.4;lymphoid tissue: 85.7" "Cell type enriched" "Detected in some" 302 "Plasma cells: 2604.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 220.0;naive B-cell: 78.9" "Lineage enriched" "Detected in many" 7 "B-cells: 220.0" "Group enriched" "Detected in some" 71 "U-266/70: 183.9;U-266/84: 593.2" HPA047702 Approved NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (8.06e-4)" "unprognostic (1.69e-3)" "unprognostic (1.19e-1)" "prognostic favorable (1.41e-4)" "unprognostic (1.26e-1)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (8.68e-2)" "unprognostic (2.61e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.12e-6)" "unprognostic (2.80e-2)" "unprognostic (3.83e-1)" "unprognostic (1.58e-1)" "unprognostic (4.41e-1)" 0.4 1.3 0.3 45.8 0.4 11.8 28.5 0.1 0.6 3.4 0.2 100.4 33.9 0.9 0.0 1.3 0.7 24.7 1.3 0.3 0.4 0.6 2.6 7.5 23.8 0.3 0.2 3.3 1.2 0.0 0.0 0.1 0.2 1.6 59.5 0.0 29.4 1.6 0.0 0.6 27.7 4.1 0.1 19.3 34.0 0.4 0.2 10.3 1.2 0.0 85.7 24.4 0.8 0.5 0.5 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.4 3.8 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.5 0.2 183.9 593.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 220.0 2.8 0.1 0.1 78.9 0.0 0.1 0.1 0.1 0.0 0.2 30.0 32.7 0.3 0.4 0.1 0.6 0.3 0.4 0.3 0.2 0.2 0.1 0.2 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2604.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1805.7;lymphoid tissue: 3169.0" "Cell type enriched" "Detected in some" 219 "Plasma cells: 46306.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 588 "memory B-cell: 3036.3;naive B-cell: 3070.9" "Lineage enriched" "Detected in all" 591 "B-cells: 3070.9" "Cell line enhanced" "Detected in some" "Daudi: 14.9;RPMI-8226: 10.4;SH-SY5Y: 6.9;U-266/70: 7.5" "Immunoglobulin genes" NA NA 8500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.41e-5)" "unprognostic (9.19e-2)" "unprognostic (4.29e-3)" "unprognostic (5.42e-3)" "unprognostic (2.08e-2)" "prognostic favorable (8.25e-4)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (3.71e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" 55.9 296.3 0.4 1054.1 0.9 342.1 665.2 0.4 3.4 145.2 2.4 1805.7 1769.7 46.8 19.4 195.7 41.3 188.2 51.9 0.4 1.2 35.0 76.1 302.3 816.8 1.9 0.8 86.5 28.3 2.5 2.8 1.0 3.5 43.9 1318.2 0.1 701.8 89.6 1.0 8.6 1023.0 66.4 3.6 972.3 1125.7 125.7 0.7 405.1 51.0 0.1 3169.0 758.2 19.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.0 3.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.6 3.6 0.3 0.0 0.0 1.4 2.2 10.4 0.0 0.0 4.0 6.9 2.3 0.0 0.0 0.0 0.0 0.7 2.6 0.0 0.8 1.1 1.0 7.5 0.2 0.8 0.0 1.2 0.0 3.9 3.2 5.1 1.6 0.9 1.7 3036.3 1.9 1.1 2.8 3070.9 2.1 1.3 2.4 1.6 2.4 2.3 1.7 344.9 0.4 0.9 0.4 3.4 0.4 1.2 1.9 0.8 3.5 3.6 0.7 1.5 0.0 0.0 0.0 0.0 210.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 17.0 40.2 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 46306.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 15.7 0.0 0.1 0.0 IGKV5-2 "B2, IGKV52" ENSG00000211599 "Immunoglobulin kappa variable 5-2" P06315 2 88897232-88897784 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9;lymphoid tissue: 83.1" "Cell type enriched" "Detected in some" 193 "Plasma cells: 1664.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "memory B-cell: 21.4;naive B-cell: 17.2" "Lineage enriched" "Detected in many" 21 "B-cells: 21.4" "Group enriched" "Detected in some" 19 "Daudi: 4.2;HDLM-2: 1.8;RPMI-8226: 2.3" "Low region specificity" "Detected in all" "Immunoglobulin genes" NA NA 4700000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.77e-3)" "unprognostic (1.26e-2)" "unprognostic (1.34e-1)" "unprognostic (2.49e-2)" "prognostic favorable (2.12e-4)" "unprognostic (2.37e-1)" "unprognostic (2.26e-1)" "unprognostic (1.29e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.62e-6)" "unprognostic (2.60e-1)" "unprognostic (2.99e-2)" "unprognostic (1.52e-1)" "unprognostic (7.85e-2)" 0.9 0.0 0.0 10.3 0.0 6.4 19.6 0.0 0.0 5.3 0.0 23.3 35.9 0.8 0.0 4.0 0.9 0.9 0.1 0.0 0.0 0.9 1.0 6.3 17.3 0.0 0.0 0.4 0.4 0.5 0.0 0.0 0.0 0.6 11.1 0.0 14.9 1.9 0.0 0.5 14.3 0.2 0.0 23.5 15.3 0.0 0.0 3.0 1.0 0.0 83.1 4.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1664.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGKV6-21 "A26, IGKV621" ENSG00000211611 "Immunoglobulin kappa variable 6-21 (non-functional)" A0A0C4DH24 2 89159751-89160366 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.3;lymphoid tissue: 141.0" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1715.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 194 "memory B-cell: 28.8;naive B-cell: 9.8" "Lineage enriched" "Detected in single" 289 "B-cells: 28.8" "Cell line enriched" "Detected in some" 6 "U-266/70: 10.5" "Immunoglobulin genes" NA NA 250000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.82e-4)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "unprognostic (2.32e-2)" "unprognostic (1.51e-3)" "unprognostic (1.93e-1)" "unprognostic (6.32e-2)" "unprognostic (4.74e-2)" "unprognostic (8.91e-2)" "unprognostic (7.31e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" 2.2 0.4 0.0 41.6 0.0 12.0 37.4 0.0 0.1 3.3 0.0 97.3 38.8 1.8 0.6 8.4 1.9 5.9 0.5 0.0 0.0 2.7 2.6 11.9 64.4 0.2 0.0 2.1 0.8 0.0 0.1 0.0 0.0 1.5 79.3 0.0 43.5 9.0 0.0 0.5 38.5 5.0 0.1 63.8 36.3 0.9 0.0 10.2 3.5 0.0 141.0 37.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1715.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV6D-21 "A10, IGKV6D21" ENSG00000225523 "Immunoglobulin kappa variable 6D-21 (non-functional)" A0A0A0MT36 2 90021567-90022185 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 67.0;lymphoid tissue: 152.7;urinary bladder: 227.3" "Cell type enriched" "Detected in some" 7 "Plasma cells: 234.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 154 "memory B-cell: 14.2;naive B-cell: 16.5" "Lineage enriched" "Detected in single" 166 "B-cells: 16.5" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.95e-4)" "unprognostic (5.47e-3)" "unprognostic (2.85e-3)" "prognostic favorable (5.25e-5)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (3.45e-7)" "unprognostic (7.23e-2)" "unprognostic (2.00e-1)" "unprognostic (1.24e-1)" "unprognostic (2.07e-1)" 1.1 0.4 0.0 17.2 0.0 17.2 11.8 0.0 0.1 5.4 0.0 67.0 38.8 1.6 0.0 22.1 0.8 2.7 2.1 0.2 0.0 1.6 2.4 6.3 19.8 0.6 0.0 1.1 1.1 0.0 0.0 0.0 0.1 0.8 31.8 0.0 21.1 17.3 0.0 1.2 37.8 1.0 0.0 45.3 13.4 3.4 0.0 9.1 1.4 0.0 152.7 227.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 234.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV6D-41 ENSG00000211626 "Immunoglobulin kappa variable 6D-41 (non-functional)" A0A0C4DH26 2 90069662-90070238 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.7;intestine: 3.4;lymphoid tissue: 2.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 0.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "memory B-cell: 3.0;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 49 "B-cells: 4.9" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 32000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.64e-2)" "unprognostic (4.43e-1)" 0.0 1.3 0.0 1.3 0.0 0.0 0.1 0.0 0.0 4.7 0.0 3.4 0.9 0.0 0.0 0.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.5 1.1 0.2 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ2 ENSG00000211676 "Immunoglobulin lambda joining 2" 22 22899481-22899655 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 260.8;lymphoid tissue: 189.8;stomach 1: 212.7" "Cell type enriched" "Detected in single" 5 "Plasma cells: 1.7" "Group enriched" "Detected in many" 8 "colorectal cancer: 12.9;endometrial cancer: 21.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "memory B-cell: 876.1;naive B-cell: 864.5" "Lineage enriched" "Detected in many" 12 "B-cells: 876.1" "Cell line enhanced" "Detected in some" "Daudi: 10.8;HMC-1: 34.1;RH-30: 89.7;U-698: 19.8" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.99e-3)" "unprognostic (5.36e-2)" "unprognostic (5.54e-2)" "unprognostic (1.13e-2)" "unprognostic (5.94e-7)" "unprognostic (1.51e-2)" "unprognostic (3.63e-2)" "unprognostic (3.66e-2)" "unprognostic (5.17e-2)" "unprognostic (2.92e-1)" 8.4 54.9 0.2 173.0 0.0 25.4 11.2 0.1 0.8 6.1 0.1 134.5 260.8 2.9 4.2 13.5 1.0 12.5 2.9 0.1 0.2 2.1 6.9 21.5 94.5 0.3 0.0 4.7 5.9 0.1 0.0 0.0 0.9 4.0 31.1 0.0 75.6 4.2 0.0 0.2 206.0 1.9 0.1 128.3 212.7 2.3 0.0 15.5 0.3 0.0 189.8 60.8 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.7 89.7 1.3 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.0 0.0 0.6 19.8 0.0 0.5 0.0 1.4 1.9 0.6 0.4 0.2 0.7 876.1 0.3 0.3 0.9 864.5 0.2 0.4 9.3 0.7 0.8 71.8 0.5 136.5 0.2 0.0 0.1 0.8 0.1 0.2 0.3 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLL1 "14.1, CD179B, IGL5, IGLL, IGVPB" ENSG00000128322 "Immunoglobulin lambda like polypeptide 1" P15814 22 23573125-23580302 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 70.0;testis: 25.2" "Group enriched" "Detected in some" 6 "Early spermatids: 78.0;Late spermatids: 140.7;Melanocytes: 119.2" "Group enriched" "Detected in some" 5 "endometrial cancer: 0.5;lung cancer: 0.5;stomach cancer: 2.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 12.0;naive B-cell: 14.8" "Lineage enriched" "Detected in many" 11 "B-cells: 14.8" "Cell line enriched" "Detected in some" 32 "REH: 787.7" "HPA051134, HPA071406" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 48000000000 "Cluster 24: B-cells - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA051134: AB_2681356, HPA071406: AB_2686393" "unprognostic (6.21e-2)" "unprognostic (5.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.75e-2)" "unprognostic (1.56e-1)" "unprognostic (5.91e-6)" "unprognostic (1.08e-1)" "unprognostic (5.27e-2)" "unprognostic (6.17e-3)" "unprognostic (5.89e-2)" "unprognostic (9.07e-2)" "unprognostic (1.99e-4)" "unprognostic (2.35e-2)" "unprognostic (5.16e-1)" "unprognostic (2.28e-2)" "unprognostic (1.21e-2)" 0.0 0.0 0.3 0.3 0.3 70.0 0.0 0.3 0.4 0.0 0.4 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.1 1.4 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.2 25.2 0.2 10.1 0.0 0.0 1.9 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 24.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 14.3 2.6 0.0 0.0 0.0 787.7 0.3 17.3 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.1 6.2 0.0 0.0 0.3 0.3 0.0 0.6 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.8 0.3 0.3 0.3 0.4 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.4 0.0 0.0 0.0 0.8 0.3 0.2 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.9 0.0 78.0 0.2 0.3 0.3 0.0 10.5 0.3 0.0 0.4 0.6 0.0 0.5 0.0 0.2 0.7 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 140.7 1.2 0.4 119.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.3 0.0 6.2 0.0 0.0 0.0 1.5 0.3 17.1 0.6 0.0 0.3 0.0 17.9 0.1 0.0 0.2 IGLL5 ENSG00000254709 "Immunoglobulin lambda like polypeptide 5" B9A064 22 22887780-22896111 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 408.3;lymphoid tissue: 674.1;stomach 1: 308.1" "Cell type enriched" "Detected in some" 55 "Melanocytes: 93931.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 226 "memory B-cell: 515.9;naive B-cell: 615.5" "Lineage enriched" "Detected in many" 246 "B-cells: 615.5" "Group enriched" "Detected in some" 7 "Daudi: 637.2;U-266/70: 386.4;U-698: 441.1" "Secreted to blood" NA NA 53000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "prognostic favorable (6.10e-4)" "unprognostic (7.64e-3)" "unprognostic (4.33e-2)" "unprognostic (1.51e-3)" "unprognostic (2.82e-2)" "prognostic favorable (3.41e-5)" "unprognostic (1.76e-2)" "unprognostic (2.18e-1)" "unprognostic (7.28e-2)" "unprognostic (1.87e-2)" "unprognostic (1.01e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (5.94e-8)" "unprognostic (1.85e-1)" "unprognostic (4.63e-1)" "unprognostic (8.52e-2)" "unprognostic (6.50e-2)" 16.3 25.1 0.3 164.8 0.2 94.4 139.3 0.1 1.2 32.8 0.4 405.6 408.3 7.8 0.0 50.4 14.7 67.3 11.2 0.1 0.1 17.0 15.9 65.7 308.5 0.4 0.1 18.6 11.0 1.5 1.5 0.2 0.2 8.3 249.4 0.1 279.3 22.2 0.5 2.7 181.5 8.8 0.4 458.8 308.1 4.3 0.2 123.6 26.2 0.2 674.1 223.5 10.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 637.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.3 3.6 0.9 0.0 0.0 0.6 1.0 0.4 0.0 0.1 0.0 0.0 0.9 1.4 0.0 1.9 0.1 0.2 386.4 68.5 441.1 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.2 515.9 0.2 0.2 0.8 615.5 0.1 0.2 1.0 0.2 0.4 2.5 0.3 68.1 0.3 0.2 0.1 1.2 0.1 0.1 0.4 0.1 0.2 0.4 0.2 0.5 0.0 3.2 30.9 0.0 222.5 108.6 0.0 0.0 0.0 0.0 1.4 0.1 0.0 1.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 12.7 1.2 5.7 0.0 0.0 0.0 7.7 3.1 0.0 11.4 0.1 1.1 4.2 0.0 0.0 0.0 0.1 0.0 0.8 113.1 3.8 0.0 0.9 93931.2 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 1680.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 93.5 0.0 49.3 0.0 2.4 0.0 IGLON5 LOC402665 ENSG00000142549 "IgLON family member 5" A6NGN9 19 51311848-51330354 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.2;retina: 13.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 24.4;Horizontal cells: 79.1;Inhibitory neurons: 17.6;Spermatogonia: 9.7" "Group enriched" "Detected in many" 5 "glioma: 9.2;ovarian cancer: 3.5;testis cancer: 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 35.0;NTERA-2: 16.0;SH-SY5Y: 23.0;SuSa: 9.9;U-2 OS: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041994 Approved "Secreted in brain" NA NA 15000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "HPA041994: AB_10794641" "unprognostic (2.09e-1)" "unprognostic (5.76e-2)" "unprognostic (1.80e-2)" "unprognostic (8.87e-3)" "unprognostic (2.33e-1)" "unprognostic (2.66e-1)" "unprognostic (3.47e-4)" "unprognostic (6.38e-5)" "unprognostic (4.54e-2)" "unprognostic (7.89e-3)" "unprognostic (1.59e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (5.62e-7)" "unprognostic (1.77e-2)" "unprognostic (9.28e-2)" "unprognostic (1.36e-2)" "unprognostic (1.86e-3)" 1.7 1.7 11.5 0.2 9.0 0.7 0.9 23.4 21.6 0.5 1.1 0.6 0.1 0.1 0.7 4.2 0.1 0.2 0.3 11.7 17.1 0.4 1.9 0.2 0.0 47.2 19.1 1.2 0.2 1.8 1.2 0.4 44.9 0.2 0.0 13.9 0.7 0.7 0.0 0.6 0.3 0.1 16.5 0.1 0.2 8.0 22.2 0.0 0.2 0.0 0.0 0.4 1.2 10.8 0.0 0.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.6 0.0 0.4 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.1 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 16.0 0.2 0.0 0.0 0.0 3.5 0.0 0.1 0.1 23.0 0.0 0.0 0.0 9.9 0.2 2.2 0.0 0.0 6.4 0.1 0.0 0.2 0.3 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.5 9.0 23.4 21.6 11.7 17.1 47.2 19.1 44.9 16.5 22.2 10.8 2.1 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 24.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.9 0.0 0.0 6.2 0.0 0.0 0.2 0.0 0.0 0.0 0.4 1.8 0.1 0.3 79.1 17.6 0.0 0.0 0.0 0.0 2.8 0.0 1.1 0.0 3.7 0.0 2.5 0.0 5.5 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.9 0.9 9.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGLV1-36 ENSG00000211655 "Immunoglobulin lambda variable 1-36" A0A0B4J1U3 22 22431958-22432465 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 268.7;stomach 1: 122.4;urinary bladder: 86.4" "Cell type enriched" "Detected in some" 13 "Plasma cells: 59.2" "Cancer enhanced" "Detected in many" "lung cancer: 33.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "memory B-cell: 60.9;naive B-cell: 85.8" "Lineage enriched" "Detected in single" 731 "B-cells: 85.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 980000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.55e-4)" "unprognostic (5.15e-2)" "unprognostic (2.04e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.11e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (6.51e-2)" "unprognostic (2.12e-1)" "unprognostic (4.53e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (2.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.07e-1)" 1.8 0.3 0.0 19.6 0.0 14.4 23.7 0.0 0.1 6.0 0.0 28.2 21.6 0.7 0.6 10.5 9.1 7.3 6.0 0.0 0.0 3.3 3.3 8.7 16.6 0.0 0.0 1.7 1.1 0.0 0.1 0.0 0.0 1.6 44.7 0.0 37.3 3.0 0.0 0.6 12.3 0.8 0.0 108.1 122.4 0.3 0.0 30.5 2.8 0.0 268.7 86.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 60.9 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1291.5;stomach 1: 1287.4" "Cell type enriched" "Detected in some" 358 "Plasma cells: 43406.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.0" "Group enriched" "Detected in some" 496 "memory B-cell: 666.4;naive B-cell: 576.7" "Lineage enriched" "Detected in many" 532 "B-cells: 666.4" "Cell line enhanced" "Detected in some" "Daudi: 3.5;RPMI-8226: 2.2;SH-SY5Y: 3.4;TIME: 2.3" "Immunoglobulin genes" NA NA 2300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.64e-3)" "unprognostic (4.68e-3)" "unprognostic (3.88e-2)" "unprognostic (3.37e-3)" "unprognostic (9.60e-3)" "prognostic favorable (5.74e-6)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (5.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" 43.4 13.0 0.8 203.5 0.5 114.3 138.5 0.1 3.0 68.1 1.1 553.8 551.6 14.8 0.6 125.4 21.5 236.0 15.2 0.2 0.2 28.8 28.3 115.4 282.5 0.3 0.2 56.6 10.0 1.1 3.4 0.6 0.6 46.1 336.7 4.2 413.8 19.7 1.2 3.1 287.2 14.3 0.2 1029.8 1287.4 7.2 0.3 179.2 61.2 0.0 1291.5 464.8 19.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 1.0 1.1 0.0 0.0 0.2 0.8 2.2 0.0 0.0 1.3 3.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.4 0.7 0.7 1.1 1.1 0.8 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.6 666.4 0.3 0.3 0.6 576.7 0.1 0.2 1.2 0.3 0.3 0.6 0.4 53.7 0.8 0.5 0.1 3.0 0.2 0.2 0.3 0.2 0.6 0.2 0.3 1.0 0.0 0.0 0.0 0.0 121.0 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 1.2 8.0 0.0 0.0 0.0 28.6 64.2 0.0 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 43406.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 7.4 0.0 0.1 0.0 IGLV1-44 ENSG00000211651 "Immunoglobulin lambda variable 1-44" P01699 22 22380766-22381347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 589.7;lymphoid tissue: 1918.7;stomach 1: 534.3" "Cell type enriched" "Detected in some" 108 "Plasma cells: 12023.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 840 "memory B-cell: 968.8;naive B-cell: 850.4" "Lineage enriched" "Detected in many" 894 "B-cells: 968.8" "Cell line enhanced" "Detected in some" "Daudi: 21.3;RPMI-8226: 5.5;SCLC-21H: 4.1;U-698: 15.2" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.88e-3)" "unprognostic (1.51e-2)" "unprognostic (2.40e-2)" "unprognostic (7.23e-3)" "unprognostic (4.81e-3)" "prognostic favorable (4.71e-5)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-8)" "unprognostic (1.85e-1)" "unprognostic (1.98e-1)" "unprognostic (6.48e-2)" "unprognostic (5.49e-2)" 33.9 2.0 0.1 297.2 0.0 133.4 110.2 0.0 0.8 14.3 0.0 378.7 589.7 11.8 0.0 80.1 19.5 78.7 17.5 0.0 0.0 18.7 17.1 122.2 519.5 1.3 0.2 15.3 3.6 0.0 2.6 0.0 0.4 13.8 263.1 0.0 273.0 9.4 0.7 2.4 236.5 21.4 0.0 608.7 534.3 11.6 0.1 117.8 35.1 0.0 1918.7 240.5 16.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.5 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 968.8 0.0 0.0 0.7 850.4 0.0 0.0 0.0 0.0 0.1 1.0 0.1 100.0 0.1 0.0 0.0 0.8 0.0 0.0 1.3 0.2 0.4 0.0 0.1 0.8 0.0 0.0 0.6 0.0 111.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.7 0.0 0.0 0.0 3.5 48.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12023.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.3 0.0 IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 706.6;lymphoid tissue: 1804.0;stomach 1: 625.5" "Cell type enriched" "Detected in some" 114 "Plasma cells: 10777.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 638 "memory B-cell: 1518.1;naive B-cell: 819.6" "Lineage enriched" "Detected in many" 828 "B-cells: 1518.1" "Cell line enhanced" "Detected in some" "HL-60: 2.1;RH-30: 2.1;RPMI-8226: 4.2;SCLC-21H: 2.7;SH-SY5Y: 2.4;U-698: 7.1" "Immunoglobulin genes" NA NA 3000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.19e-3)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.66e-4)" "unprognostic (4.44e-2)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.12e-8)" "unprognostic (5.00e-3)" "unprognostic (1.62e-1)" "unprognostic (7.08e-2)" "unprognostic (1.15e-2)" 36.0 216.0 0.6 323.0 0.4 162.3 200.5 0.4 2.3 82.1 0.7 706.6 704.7 23.8 3.0 163.7 21.3 112.7 27.2 0.2 0.5 23.2 31.8 126.7 689.2 2.6 0.4 43.5 8.9 4.9 2.1 0.5 1.2 22.5 531.5 0.2 526.6 70.2 0.7 4.7 332.8 34.7 0.5 813.7 625.5 9.8 0.4 260.1 34.1 0.0 1804.0 367.0 10.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.7 2.1 4.2 0.0 0.0 2.7 2.4 0.5 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.6 0.0 7.1 0.0 0.9 0.0 0.7 1.2 0.5 0.7 0.1 0.5 1518.1 0.7 0.6 1.0 819.6 0.3 0.6 0.6 0.5 0.5 1.8 0.6 159.6 0.6 0.4 0.4 2.3 0.2 0.5 2.6 0.4 1.2 0.5 0.4 2.4 0.0 0.0 0.0 0.0 94.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 1.7 29.0 0.0 0.0 0.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10777.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 IGLV1-50 ENSG00000211645 "Immunoglobulin lambda variable 1-50 (non-functional)" A0A075B6I6 22 22327300-22327814 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 16.4;lymphoid tissue: 14.7;stomach 1: 20.4" "Cell type enriched" "Detected in single" 2575 "Plasma cells: 1545.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 21 "memory B-cell: 11.0;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 33 "B-cells: 11.0" "Cell line enhanced" "Detected in single" "HEK 293: 1.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-4)" "unprognostic (8.01e-2)" "unprognostic (1.28e-3)" "unprognostic (6.91e-2)" "unprognostic (2.10e-1)" "prognostic favorable (7.08e-4)" "unprognostic (2.81e-1)" "unprognostic (2.41e-1)" "unprognostic (2.02e-1)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (7.38e-2)" "unprognostic (1.58e-4)" "unprognostic (4.89e-3)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-2)" 0.5 0.5 0.1 6.1 0.1 3.3 6.7 1.7 1.9 0.5 0.0 5.4 16.4 0.6 1.2 2.4 0.5 0.8 0.0 0.6 0.0 0.2 0.2 4.4 1.9 0.6 0.0 0.9 0.1 0.1 0.1 0.0 0.6 0.3 4.5 0.7 4.6 0.3 0.4 0.0 9.4 0.2 0.0 3.9 20.4 0.4 0.0 0.6 0.2 0.0 14.7 9.3 0.1 1.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.3 0.5 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.1 0.0 0.3 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 1.7 1.9 0.6 0.0 0.6 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1545.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-51 ENSG00000211644 "Immunoglobulin lambda variable 1-51" P01701 22 22322472-22322969 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1318.8;lymphoid tissue: 3027.3;urinary bladder: 1584.8" "Cell type enriched" "Detected in some" 312 "Plasma cells: 34336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 275.9;naive B-cell: 178.3" "Lineage enriched" "Detected in many" 10 "B-cells: 275.9" "Cell line enhanced" "Detected in many" "HEK 293: 17.9" "Immunoglobulin genes" NA NA 1700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.85e-4)" "unprognostic (1.71e-2)" "unprognostic (3.12e-3)" "unprognostic (1.76e-3)" "unprognostic (1.61e-1)" "prognostic favorable (1.95e-5)" "unprognostic (3.55e-3)" "unprognostic (3.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.21e-1)" "unprognostic (5.70e-2)" "unprognostic (1.89e-1)" "unprognostic (1.07e-1)" 43.5 318.8 1.1 484.8 1.9 274.1 627.0 4.6 7.1 73.2 2.0 1318.8 1139.1 38.0 16.9 287.4 52.8 238.0 70.2 1.4 1.6 32.7 53.3 179.1 343.1 4.0 1.4 185.0 39.0 5.8 4.1 1.5 4.2 34.4 930.0 3.1 695.2 49.5 1.9 13.1 702.1 49.8 1.9 934.5 956.7 11.7 1.5 274.0 63.0 1.7 3027.3 1584.8 17.7 2.7 1.3 0.6 1.6 3.8 3.5 1.7 5.9 1.4 3.2 3.1 2.0 2.3 1.0 8.8 1.6 0.8 1.1 3.1 1.9 3.8 2.2 1.4 17.9 3.9 4.5 2.4 0.7 3.4 1.7 5.2 1.0 2.7 0.3 0.4 3.1 0.9 3.9 0.9 3.0 1.6 2.6 3.8 3.0 2.8 4.1 2.3 2.7 8.8 3.6 1.4 8.3 4.9 2.0 1.4 1.8 0.9 2.7 0.3 4.3 4.4 9.2 1.0 1.2 2.0 2.0 2.0 0.4 2.8 0.8 0.1 0.5 0.0 0.2 0.2 26.3 275.9 0.2 0.3 0.1 178.3 0.7 0.5 0.4 0.1 0.3 0.2 0.2 26.4 1.1 1.9 4.6 7.1 1.4 1.6 4.0 1.4 4.2 1.9 1.5 2.7 0.0 0.0 0.5 0.0 109.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 4.8 35.7 0.1 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34336.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 19.3 0.0 0.0 9.4 0.0 0.0 0.0 IGLV10-54 ENSG00000211642 "Immunoglobulin lambda variable 10-54" A0A075B6I4 22 22038643-22215270 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 121.9;intestine: 324.6;lymphoid tissue: 329.7;salivary gland: 253.6;stomach 1: 194.5" "Cell type enriched" "Detected in some" 17 "Plasma cells: 358.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 2.2" "Group enriched" "Detected in some" 32 "memory B-cell: 60.0;naive B-cell: 35.2" "Lineage enriched" "Detected in many" 41 "B-cells: 60.0" "Cell line enhanced" "Detected in single" "TIME: 2.3" "Immunoglobulin genes" NA NA 54000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.35e-5)" "unprognostic (2.65e-2)" "unprognostic (9.06e-2)" "unprognostic (8.71e-3)" "unprognostic (1.29e-1)" "prognostic favorable (8.30e-5)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" "unprognostic (5.62e-1)" "unprognostic (1.18e-1)" "unprognostic (3.22e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (3.33e-1)" "unprognostic (5.57e-2)" "unprognostic (5.17e-2)" "unprognostic (3.86e-1)" 3.6 1.9 0.1 96.4 0.3 33.8 121.9 0.1 2.2 2.0 0.8 324.6 294.8 1.5 0.0 22.5 24.3 21.9 12.0 0.1 0.3 2.5 7.0 22.3 64.7 1.4 0.1 2.6 11.6 0.0 0.4 0.4 0.2 6.4 155.1 0.0 253.6 2.3 0.1 1.0 138.9 12.7 0.2 155.3 194.5 0.4 0.1 22.9 2.5 0.0 329.7 21.8 4.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 60.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.1 0.3 0.1 2.2 0.1 0.3 1.4 0.1 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV11-55 ENSG00000211641 "Immunoglobulin lambda variable 11-55 (non-functional)" A0A075B6I3 22 22201663-22202161 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.1" "Cell type enhanced" "Detected in some" "Late spermatids: 3.5;Plasma cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Daudi: 8.6;U-698: 2.7" "Immunoglobulin genes" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.22e-1)" "unprognostic (6.16e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1542.6;lymphoid tissue: 2926.9" "Cell type enriched" "Detected in some" 85 "Plasma cells: 7693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1402.5;naive B-cell: 850.1" "Lineage enriched" "Detected in many" 46 "B-cells: 1402.5" "Cell line enhanced" "Detected in some" "Karpas-707: 75.0;U-266/70: 20.9;U-266/84: 15.3" "Immunoglobulin genes" NA NA 980000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.76e-3)" "unprognostic (6.86e-2)" "unprognostic (3.46e-3)" "unprognostic (7.67e-3)" "unprognostic (2.82e-3)" "prognostic favorable (4.74e-5)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (9.19e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (3.93e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (2.27e-1)" 33.6 7.3 0.6 344.7 0.3 157.3 447.8 0.1 2.7 27.7 0.8 1455.8 1542.6 18.4 0.5 212.0 30.0 191.3 44.6 0.2 0.7 22.4 41.1 179.8 680.1 1.5 0.2 30.5 22.4 0.6 2.1 0.5 1.1 17.0 868.3 0.0 425.0 36.0 1.7 2.9 713.8 21.3 0.6 637.7 876.1 75.4 0.5 286.4 62.2 0.0 2926.9 661.1 14.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 3.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 75.0 0.0 0.0 0.9 4.6 1.1 0.0 0.0 0.8 2.8 8.3 0.0 0.0 2.9 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 1.1 0.3 1.6 20.9 15.3 0.0 0.3 1.1 0.0 1.2 1.0 0.7 11.5 0.2 1.4 1402.5 1.5 5.9 0.9 850.1 1.0 4.6 30.2 11.1 0.8 0.9 0.8 149.8 0.6 0.3 0.1 2.7 0.2 0.7 1.5 0.2 1.1 0.6 0.5 2.2 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 15.8 0.0 0.0 0.0 1.4 11.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7693.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2622.2;lymphoid tissue: 5374.9;stomach 1: 2530.1" "Cell type enriched" "Detected in some" 179 "Plasma cells: 58316.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 3655.3;naive B-cell: 2657.4" "Lineage enriched" "Detected in all" 58 "B-cells: 3655.3" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 22672.4" "Immunoglobulin genes" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.23e-4)" "unprognostic (9.05e-3)" "unprognostic (1.18e-2)" "unprognostic (7.20e-3)" "unprognostic (2.00e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.69e-1)" "unprognostic (1.97e-1)" "unprognostic (7.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.11e-2)" "unprognostic (4.97e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" 83.9 192.1 0.8 754.9 1.7 357.8 749.8 0.5 6.4 119.7 3.8 2622.2 2470.7 47.8 20.7 245.2 49.0 442.1 45.2 0.6 1.0 54.3 102.1 399.3 3320.0 1.6 0.6 75.3 52.1 4.5 5.6 1.2 1.0 71.0 1074.1 0.1 797.3 119.4 2.7 21.3 1262.7 62.0 1.4 1580.6 2530.1 13.9 1.3 586.1 116.5 0.5 5374.9 1165.2 35.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.4 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.8 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4453.2 0.0 0.0 8.7 8.0 1.7 0.0 0.0 4.9 3.7 22672.4 0.0 0.0 11.8 11.1 0.4 17.3 0.0 0.0 7.1 0.0 5.1 0.0 4.1 5.7 1.1 20.4 37.7 1.4 12.1 1.7 5.0 3.9 5.3 1.7 47.1 1.0 28.8 3655.3 9.6 53.9 3.3 2657.4 1.4 12.7 11.6 62.5 2.4 2.2 2.1 451.3 0.8 1.7 0.5 6.4 0.6 1.0 1.6 0.6 1.0 1.4 1.3 2.1 0.0 0.0 0.0 0.0 324.1 0.0 0.0 0.0 1.2 0.0 0.3 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 14.7 0.0 0.0 0.0 9.9 121.8 0.0 0.0 0.0 1.4 1.7 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 58316.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 36.6 0.0 0.8 0.0 IGLV2-18 ENSG00000211664 "Immunoglobulin lambda variable 2-18" A0A075B6J9 22 22734607-22735089 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 271.5;lymphoid tissue: 224.4" "Cell type enriched" "Detected in some" 210 "Plasma cells: 2488.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "memory B-cell: 321.2;naive B-cell: 126.9" "Lineage enriched" "Detected in many" 64 "B-cells: 321.2" "Group enriched" "Detected in some" 7 "RPMI-8226: 13.4;U-266/70: 22.3;U-266/84: 7.2" "Immunoglobulin genes" NA NA 570000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.06e-5)" "unprognostic (2.81e-2)" "unprognostic (7.47e-3)" "unprognostic (1.13e-2)" "prognostic favorable (7.75e-4)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (7.58e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (1.95e-1)" "unprognostic (9.70e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-2)" 3.4 0.3 0.0 73.0 0.0 23.7 67.1 0.0 0.3 6.7 0.1 271.5 262.0 4.2 0.0 39.6 10.8 36.3 12.5 0.0 0.0 2.0 2.8 12.6 37.6 0.1 0.0 4.1 1.1 2.1 0.2 0.1 0.4 1.7 138.6 0.0 64.3 4.9 0.1 0.3 150.2 6.5 0.0 95.8 72.5 0.5 0.0 22.1 2.8 0.0 224.4 18.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 13.4 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 22.3 7.2 0.1 0.1 0.1 0.0 0.2 1.8 0.0 1.6 0.0 0.8 321.2 0.3 1.3 0.1 126.9 0.7 0.6 0.5 5.0 0.1 0.2 0.1 69.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 7.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2488.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 691.1;lymphoid tissue: 1598.0;stomach 1: 672.8" "Cell type enriched" "Detected in some" 132 "Plasma cells: 12487.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 369 "memory B-cell: 2072.7;naive B-cell: 2596.0" "Lineage enriched" "Detected in all" 410 "B-cells: 2596.0" "Cell line enriched" "Detected in some" 10 "Karpas-707: 85411.7" "Immunoglobulin genes" NA NA 540000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" 16.0 38.9 0.7 306.7 0.3 103.6 184.7 0.1 1.5 45.2 0.6 634.1 691.1 16.2 1.3 78.7 25.5 66.8 19.9 0.2 0.1 18.6 26.2 160.8 623.2 1.0 0.1 16.3 8.2 0.6 1.7 0.6 0.4 10.8 457.1 0.0 356.7 38.1 0.5 2.1 517.3 16.1 0.3 530.5 672.8 5.9 0.2 277.6 39.1 0.4 1598.0 274.5 11.9 0.3 0.8 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 65.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 82.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 85411.7 0.0 0.0 2.2 4.2 0.5 0.0 0.0 0.7 1.9 8843.9 0.0 0.0 2.1 4.5 0.0 4.7 0.0 0.0 1.9 0.0 1.0 0.0 1.1 3.4 0.7 213.9 81.1 0.5 92.6 0.2 35.5 1.8 3.1 1.0 1.6 0.9 1.3 2072.7 1.6 0.8 2.6 2596.0 0.6 0.9 6.3 1.6 1.7 0.9 1.3 231.7 0.7 0.3 0.1 1.5 0.2 0.1 1.0 0.1 0.4 0.3 0.2 0.3 0.0 0.0 0.0 0.0 94.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.7 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 39.5 0.0 0.2 0.0 IGLV2-33 ENSG00000211656 "Immunoglobulin lambda variable 2-33 (non-functional)" A0A075B6J2 22 22588155-22588688 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.3;lymphoid tissue: 2.7;salivary gland: 2.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 2.9;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 30 "B-cells: 2.9" "Group enriched" "Detected in some" 9 "RPMI-8226: 1.5;U-266/70: 5.1;U-266/84: 3.4" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "unprognostic (1.29e-2)" "unprognostic (1.79e-3)" "unprognostic (2.13e-1)" "unprognostic (4.30e-1)" "unprognostic (2.64e-3)" "unprognostic (2.47e-2)" "unprognostic (2.06e-1)" "unprognostic (6.68e-2)" 0.0 0.1 0.0 1.5 0.0 1.3 0.4 0.0 0.0 0.0 0.0 2.2 4.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.6 0.0 0.0 0.0 2.3 0.2 0.0 1.5 1.5 0.0 0.0 0.1 0.0 0.0 2.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1141.8;lymphoid tissue: 1012.4" "Cell type enriched" "Detected in some" 80 "Plasma cells: 5288.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 125 "memory B-cell: 1439.0;naive B-cell: 2097.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2097.3" "Group enriched" "Detected in many" 617 "U-266/70: 64161.5;U-266/84: 56786.5" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.92e-4)" "unprognostic (1.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "prognostic favorable (5.07e-5)" "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (6.55e-2)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.04e-2)" "unprognostic (2.67e-1)" "unprognostic (9.90e-2)" "unprognostic (1.62e-1)" 18.7 7.0 1.1 325.0 0.6 96.0 155.2 0.3 2.4 26.0 1.7 1141.8 977.0 9.4 3.5 91.4 7.9 132.4 30.5 0.3 0.3 15.4 24.3 59.2 228.2 0.8 0.3 57.2 30.3 1.4 1.4 0.2 0.7 9.0 250.6 0.0 255.5 60.3 0.6 1.9 451.5 20.1 0.8 437.7 433.9 3.4 0.3 90.6 23.7 0.0 1012.4 259.0 10.3 1.0 62.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 7.6 0.0 0.0 23.1 0.0 0.0 0.0 22.3 0.0 0.5 0.0 0.0 0.0 0.7 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 11.3 1.9 14.8 0.0 0.0 97.9 0.9 10.1 0.0 0.0 1.4 2.8 0.2 0.0 9.3 0.0 0.0 29.5 0.9 0.0 9.8 0.6 38.9 64161.5 56786.5 20.4 0.0 10.1 0.0 1.2 2.4 0.6 2.1 0.7 0.9 1439.0 1.3 1.5 1.9 2097.3 0.4 1.0 14.1 1.3 1.4 0.6 0.7 174.0 1.1 0.6 0.3 2.4 0.3 0.3 0.8 0.3 0.7 0.8 0.3 1.0 0.0 3.2 0.0 0.0 65.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 2.5 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5288.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.2 0.0 IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1234.9;lymphoid tissue: 3325.7;stomach 1: 1460.4" "Cell type enriched" "Detected in some" 321 "Plasma cells: 56277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 725 "memory B-cell: 779.5;naive B-cell: 1038.5" "Lineage enriched" "Detected in many" 828 "B-cells: 1038.5" "Cell line enhanced" "Detected in some" "Daudi: 14.4;RPMI-8226: 4.5;SCLC-21H: 9.1;SH-SY5Y: 9.9" HPA003285 Approved "Immunoglobulin genes" NA NA 4300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (9.70e-5)" "unprognostic (9.06e-2)" "unprognostic (5.39e-3)" "unprognostic (2.37e-2)" "unprognostic (8.13e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.92e-2)" "unprognostic (1.63e-2)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (9.06e-9)" "unprognostic (2.70e-2)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" 44.5 70.9 0.3 485.2 0.2 332.4 317.1 0.2 2.0 192.0 0.9 1234.9 643.4 39.2 0.0 217.7 19.2 310.4 28.1 0.1 0.4 26.3 70.1 176.2 1117.0 1.0 0.3 34.1 7.6 2.7 2.0 0.7 1.5 21.9 684.4 0.2 627.3 19.6 1.2 4.1 481.7 37.2 0.4 654.2 1460.4 56.0 0.3 335.5 35.9 0.0 3325.7 679.7 30.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.2 2.4 0.8 0.0 0.0 0.5 3.0 4.5 0.0 0.0 9.1 9.9 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.6 1.7 1.8 1.2 2.8 0.0 0.3 0.0 0.7 1.1 0.5 0.3 0.4 0.4 779.5 0.6 0.2 1.2 1038.5 0.2 0.3 0.6 0.4 0.8 0.5 0.5 52.3 0.3 0.2 0.2 2.0 0.1 0.4 1.0 0.3 1.5 0.4 0.3 0.9 0.0 3.2 0.0 0.0 111.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 10.7 174.8 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56277.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 11.7 0.0 0.2 0.0 IGLV3-10 ENSG00000211669 "Immunoglobulin lambda variable 3-10" A0A075B6K4 22 22811747-22812281 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 317.0;lymphoid tissue: 707.7;stomach 1: 288.7" "Cell type enriched" "Detected in some" 52 "Plasma cells: 1090.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.3;medulla oblongata: 1.8" "Group enriched" "Detected in some" 786 "memory B-cell: 548.7;naive B-cell: 315.0" "Lineage enriched" "Detected in single" 998 "B-cells: 548.7" "Cell line enhanced" "Detected in some" "Daudi: 4.9;HL-60: 1.0;RH-30: 1.6" HPA003285 Approved "Immunoglobulin genes" NA NA 2000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "unprognostic (6.00e-2)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.73e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.27e-4)" "unprognostic (7.40e-3)" "unprognostic (2.44e-2)" "unprognostic (9.91e-2)" "unprognostic (9.55e-2)" "unprognostic (2.79e-1)" "unprognostic (3.55e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (9.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" 33.3 112.9 0.5 144.0 0.4 65.5 111.1 0.1 3.3 41.3 0.6 308.0 176.3 7.6 4.5 56.3 7.9 43.5 20.5 0.1 0.2 12.2 20.8 48.0 230.5 1.8 0.2 14.6 10.8 0.9 0.8 0.4 0.6 11.0 317.0 0.0 139.7 10.8 0.2 8.1 94.9 5.8 0.1 217.1 288.7 97.4 0.2 25.9 8.6 0.0 707.7 140.2 7.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.2 0.0 0.2 548.7 0.1 0.2 0.2 315.0 0.0 0.2 0.3 0.1 0.1 0.3 0.1 43.2 0.5 0.4 0.1 3.3 0.1 0.2 1.8 0.2 0.6 0.1 0.2 0.2 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 7.1 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1090.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.2 0.0 IGLV3-12 ENSG00000211667 "Immunoglobulin lambda variable 3-12" A0A075B6K2 22 22771824-22772582 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 4.2;memory B-cell: 9.2;memory CD8 T-cell: 4.0;naive B-cell: 6.7;NK-cell: 5.6" "Group enriched" "Detected in many" 64 "B-cells: 9.2;NK-cells: 5.6;T-cells: 4.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.92e-3)" "unprognostic (4.30e-2)" "unprognostic (1.68e-3)" "unprognostic (2.03e-2)" "prognostic favorable (8.39e-6)" "unprognostic (8.44e-2)" "unprognostic (4.62e-2)" "unprognostic (5.01e-2)" "unprognostic (2.88e-2)" "unprognostic (3.15e-4)" "unprognostic (3.62e-2)" "unprognostic (4.71e-1)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" 0.8 1.2 0.0 3.9 0.0 2.7 1.9 0.0 0.3 0.3 0.1 7.3 5.5 0.5 0.0 1.0 0.6 3.3 0.0 0.0 0.0 0.1 0.5 2.7 15.3 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 3.8 0.0 5.1 1.7 0.0 0.2 2.7 0.1 0.0 4.6 8.2 0.9 0.0 3.9 0.2 0.0 30.1 1.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 1.1 9.2 1.0 4.0 0.0 6.7 0.0 0.2 0.0 5.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-16 ENSG00000211665 "Immunoglobulin lambda variable 3-16" A0A075B6K0 22 22747383-22747921 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 80.3;urinary bladder: 42.9" "Group enriched" "Detected in some" 49 "B-cells: 6.2;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 393 "memory B-cell: 107.2;naive B-cell: 121.2" "Lineage enriched" "Detected in single" 417 "B-cells: 121.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 350000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (5.01e-5)" "unprognostic (2.40e-3)" "unprognostic (4.30e-3)" "unprognostic (4.05e-1)" "prognostic favorable (2.99e-5)" "unprognostic (3.88e-1)" "unprognostic (1.12e-1)" "unprognostic (9.83e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (9.08e-7)" "unprognostic (4.31e-2)" "unprognostic (3.41e-1)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" 1.5 0.0 0.0 6.9 0.0 6.3 4.9 0.0 0.0 0.7 0.0 10.7 9.9 0.2 0.0 2.5 1.9 1.2 0.6 0.0 0.0 0.7 1.3 4.7 13.6 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.6 10.8 0.0 10.8 0.0 0.0 0.1 5.2 0.6 0.0 12.8 13.0 0.3 0.0 3.5 0.2 0.0 80.3 42.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 107.2 0.0 0.1 0.1 121.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-19 ENSG00000211663 "Immunoglobulin lambda variable 3-19" P01714 22 22720623-22721145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1026.7;lymphoid tissue: 1979.7;stomach 1: 1240.2" "Cell type enriched" "Detected in some" 61 "Plasma cells: 3121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 355 "memory B-cell: 618.3;naive B-cell: 503.7" "Lineage enriched" "Detected in many" 391 "B-cells: 618.3" "Cell line enhanced" "Detected in some" "RPMI-8226: 6.2;SCLC-21H: 9.4;SH-SY5Y: 10.7;U-251 MG: 4.2" "Immunoglobulin genes" NA NA 1200000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.92e-5)" "unprognostic (1.52e-2)" "unprognostic (1.60e-3)" "prognostic favorable (6.11e-5)" "unprognostic (1.14e-1)" "unprognostic (1.24e-3)" "unprognostic (9.58e-3)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (3.13e-1)" "unprognostic (3.03e-1)" "prognostic unfavorable (9.37e-10)" "unprognostic (2.10e-1)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (8.52e-2)" 49.1 20.1 0.1 402.2 0.3 185.1 313.5 0.1 2.4 69.2 0.3 1026.7 713.6 19.0 263.4 154.0 65.8 182.4 36.9 0.1 0.3 26.0 57.5 192.2 464.9 1.5 0.4 44.9 11.5 1.3 2.7 0.4 0.4 17.2 912.2 0.0 304.9 62.4 0.9 4.8 385.2 34.9 0.6 714.2 1240.2 6.0 0.4 435.0 55.4 0.0 1979.7 642.5 13.6 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 2.7 0.3 0.0 0.0 0.1 0.9 6.2 0.0 0.0 9.4 10.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.4 0.0 4.2 0.8 0.5 0.7 0.0 0.5 0.0 0.4 0.4 1.0 0.5 0.3 0.7 618.3 0.2 0.3 0.5 503.7 0.4 0.3 1.5 0.3 0.4 0.6 0.4 36.2 0.1 0.3 0.1 2.4 0.1 0.3 1.5 0.4 0.4 0.6 0.4 1.1 0.0 0.0 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.4 15.8 0.0 1.3 0.0 2.2 1.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3121.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 IGLV3-21 ENSG00000211662 "Immunoglobulin lambda variable 3-21" P80748 22 22711689-22713203 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1812.1;urinary bladder: 773.9" "Cell type enriched" "Detected in some" 59 "Plasma cells: 5013.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 339 "memory B-cell: 432.0;naive B-cell: 224.7" "Lineage enriched" "Detected in single" 445 "B-cells: 432.0" "Cell line enriched" "Detected in some" 103 "REH: 282.7" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-3)" "unprognostic (6.04e-3)" "unprognostic (4.21e-2)" "unprognostic (2.59e-3)" "unprognostic (4.06e-3)" "prognostic favorable (3.26e-7)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "unprognostic (3.86e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (9.54e-8)" "unprognostic (7.83e-2)" "unprognostic (1.88e-1)" "unprognostic (2.67e-1)" "unprognostic (7.52e-2)" 17.6 63.4 0.3 321.9 0.2 248.2 120.7 0.1 1.6 110.0 1.6 357.4 350.4 12.9 0.5 63.1 10.2 120.4 10.8 0.1 0.2 21.5 36.4 108.6 272.7 1.0 0.1 35.6 5.7 0.7 1.4 0.4 0.4 16.8 230.8 0.0 260.8 20.2 0.5 2.3 150.7 9.0 0.3 421.0 504.5 14.4 0.3 171.6 19.9 0.0 1812.1 773.9 17.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.4 0.5 0.2 0.0 0.0 282.7 1.8 2.0 0.0 0.0 1.6 1.8 0.1 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.5 0.5 0.5 0.1 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.1 432.0 0.1 0.1 0.3 224.7 0.1 0.1 0.9 0.1 0.1 0.2 0.1 36.6 0.3 0.2 0.1 1.6 0.1 0.2 1.0 0.1 0.4 0.3 0.3 1.3 0.0 0.0 0.0 0.0 84.4 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 3.3 2.5 0.1 0.0 0.0 0.0 0.0 1.3 0.0 4.7 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5013.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.0 1.8 0.0 0.2 0.0 IGLV3-22 ENSG00000211661 "Immunoglobulin lambda variable 3-22" A0A075B6J6 22 22704265-22704822 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 2.6;lymphoid tissue: 9.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 72 "memory B-cell: 6.6;naive B-cell: 7.7" "Lineage enriched" "Detected in single" 78 "B-cells: 7.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 1100000000 "Cluster 37: B-cells - Transcription" "Cluster 63: T-cells - Adaptive immune response" "unprognostic (2.00e-1)" "unprognostic (9.93e-3)" "unprognostic (3.73e-1)" 0.0 0.7 0.0 1.0 0.0 1.5 2.6 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.8 0.3 0.0 0.0 1.4 0.0 0.0 1.4 0.8 0.3 0.0 9.5 0.0 0.0 5.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-25 ENSG00000211659 "Immunoglobulin lambda variable 3-25" P01717 22 22686726-22687271 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2440.7;stomach 1: 1015.7" "Cell type enriched" "Detected in some" 41 "Plasma cells: 17441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 45 "memory B-cell: 545.0;naive B-cell: 794.2" "Lineage enriched" "Detected in many" 53 "B-cells: 794.2" "Cell line enhanced" "Detected in some" "HL-60: 2.6;RPMI-8226: 2.7;SCLC-21H: 4.6;SH-SY5Y: 5.1" HPA003285 Approved "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (5.55e-4)" "unprognostic (8.28e-2)" "unprognostic (4.28e-3)" "unprognostic (2.89e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.43e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.87e-1)" "unprognostic (1.98e-2)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.78e-7)" "unprognostic (1.25e-1)" "unprognostic (4.78e-1)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" 56.8 163.2 0.2 293.2 0.2 243.2 430.9 0.1 1.7 151.9 1.3 847.4 338.9 20.8 2.1 161.5 49.8 177.1 29.8 0.2 0.3 17.1 45.7 870.5 1024.7 1.8 0.2 21.8 14.5 1.7 1.7 0.5 0.6 18.9 467.5 0.0 532.3 116.5 0.7 2.4 228.9 34.1 0.4 543.5 1015.7 59.8 0.5 155.9 23.1 0.0 2440.7 779.6 20.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 1.7 0.4 1.7 0.0 0.0 1.6 1.5 2.7 0.0 0.0 4.6 5.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.0 0.1 0.8 1.8 0.2 0.7 0.0 1.3 0.0 0.8 0.4 0.3 0.7 0.1 0.2 545.0 0.4 0.1 0.5 794.2 0.2 0.1 14.9 0.3 0.6 0.3 0.3 76.5 0.2 0.2 0.1 1.7 0.2 0.3 1.8 0.2 0.6 0.4 0.5 0.6 0.0 0.0 0.0 0.0 84.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 1.9 40.8 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17441.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 417.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 401.6" "Cell type enriched" "Detected in some" 135 "Plasma cells: 1406.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 719 "memory B-cell: 194.0;naive B-cell: 367.8" "Lineage enriched" "Detected in single" 941 "B-cells: 367.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 720000000 "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.45e-2)" "unprognostic (1.87e-3)" "unprognostic (5.44e-2)" "unprognostic (4.30e-3)" "prognostic favorable (3.60e-7)" "unprognostic (8.55e-2)" "unprognostic (2.16e-1)" "unprognostic (5.91e-2)" "unprognostic (9.56e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.95e-9)" "unprognostic (1.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" 8.8 1.8 0.1 16.4 0.0 29.4 29.7 0.0 0.5 23.7 0.1 56.7 19.3 2.2 0.0 10.3 5.1 10.5 3.1 0.0 0.0 3.7 3.7 29.3 64.3 0.4 0.0 2.9 0.3 0.2 0.4 0.0 0.1 2.4 26.9 0.0 40.6 0.8 0.0 0.5 24.4 0.6 0.0 103.9 59.8 24.2 0.0 47.6 2.8 0.0 401.6 27.4 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.1 194.0 0.2 0.0 0.3 367.8 0.0 0.0 0.2 0.0 0.1 0.1 0.1 11.8 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1406.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV3-32 ENSG00000211657 "Immunoglobulin lambda variable 3-32 (non-functional)" A0A0A0MS00 22 22594528-22595056 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 14: B-cells - Humoral immune response" "unprognostic (4.68e-2)" "unprognostic (1.31e-1)" "unprognostic (7.93e-2)" 0.0 0.0 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.0 0.0 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-9 ENSG00000211670 "Immunoglobulin lambda variable 3-9" A0A075B6K5 22 22819010-22819756 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 313.9;stomach 1: 117.3" "Cell type enriched" "Detected in some" 9 "Plasma cells: 13.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 51 "memory B-cell: 64.7;naive B-cell: 168.7" "Lineage enriched" "Detected in many" 74 "B-cells: 168.7" "Cell line enriched" "Detected in some" 5 "U-266/70: 41.3" HPA003285 Approved "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (2.59e-4)" "unprognostic (6.52e-3)" "unprognostic (1.95e-1)" "unprognostic (5.40e-2)" "prognostic favorable (9.80e-5)" "unprognostic (1.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.68e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.47e-2)" "unprognostic (4.58e-2)" "unprognostic (4.55e-2)" "unprognostic (3.22e-1)" 1.8 23.5 0.1 84.6 0.0 27.8 14.9 0.0 0.1 7.3 0.1 87.1 58.7 2.0 0.0 20.8 1.8 18.6 7.6 0.0 0.0 3.2 6.2 17.1 139.8 0.7 0.0 3.9 2.4 0.2 0.1 0.0 0.1 1.4 64.0 0.0 46.2 3.1 0.1 1.5 60.3 5.2 0.0 64.6 117.3 1.6 0.1 35.0 3.8 0.0 313.9 72.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 2.1 0.1 0.3 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.9 0.3 0.0 41.3 5.8 0.7 0.0 3.9 0.0 0.0 0.1 0.0 1.2 0.0 2.2 64.7 1.3 1.4 0.0 168.7 0.4 1.8 0.1 0.5 0.1 0.0 0.1 6.5 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 IGLV4-3 ENSG00000211672 "Immunoglobulin lambda variable 4-3" A0A075B6K6 22 22871507-22872035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 15.7;stomach 1: 28.9" "Cell type enriched" "Detected in some" 23 "Plasma cells: 50.3" "Cancer enhanced" "Detected in many" "lung cancer: 4.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 98 "memory B-cell: 11.7;naive B-cell: 7.8" "Lineage enriched" "Detected in single" 118 "B-cells: 11.7" "Cell line enriched" "Detected in single" 5 "Daudi: 1.3" "Immunoglobulin genes" NA NA 1600000 "Cluster 37: B-cells - Transcription" "Cluster 4: Stomach - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (7.22e-2)" "unprognostic (5.51e-3)" "unprognostic (2.71e-1)" "unprognostic (4.37e-4)" "unprognostic (1.87e-1)" "unprognostic (2.74e-1)" "unprognostic (1.49e-1)" "unprognostic (1.36e-1)" 0.2 0.0 0.0 2.1 0.0 1.4 1.6 0.0 0.0 0.3 0.0 5.1 4.5 0.3 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.1 0.1 1.0 10.1 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 3.3 0.0 2.8 0.0 0.0 0.0 3.0 0.0 0.0 5.3 28.9 0.2 0.0 1.4 0.4 0.0 15.7 0.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.1;lymphoid tissue: 116.3;urinary bladder: 185.2" "Cell type enriched" "Detected in some" 152 "Plasma cells: 1125.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 78 "memory B-cell: 79.4;naive B-cell: 48.9" "Lineage enriched" "Detected in single" 96 "B-cells: 79.4" "Group enriched" "Detected in some" 4 "Daudi: 7.8;HEL: 13.3;U-698: 3.9" "Immunoglobulin genes" NA NA 120000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.57e-4)" "unprognostic (5.46e-3)" "unprognostic (9.43e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.06e-2)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (4.19e-1)" "unprognostic (2.60e-1)" 1.8 1.9 0.0 32.9 0.0 18.1 36.6 0.0 0.2 3.3 0.1 70.7 193.1 1.5 0.0 12.3 1.9 3.4 11.4 0.0 0.0 3.1 3.9 43.5 116.3 0.0 0.0 4.6 1.1 0.4 0.2 0.2 0.1 1.1 73.3 0.0 37.9 0.8 0.1 0.1 86.8 2.1 0.0 80.3 37.7 1.7 0.0 18.3 1.7 0.0 112.0 185.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 3.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.4 0.1 0.0 0.0 48.9 0.0 0.0 0.8 0.0 0.0 0.0 0.4 3.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1125.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 430.3;lymphoid tissue: 461.2;salivary gland: 116.6;stomach 1: 285.6;urinary bladder: 204.0" "Cell type enriched" "Detected in some" 140 "Plasma cells: 4593.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.1" "Group enriched" "Detected in some" 302 "memory B-cell: 331.7;naive B-cell: 224.0" "Lineage enriched" "Detected in single" 361 "B-cells: 331.7" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 1.0;REH: 1.3;RPMI-8226: 5.4;SH-SY5Y: 1.3" "Immunoglobulin genes" NA NA 320000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.02e-4)" "unprognostic (1.32e-2)" "unprognostic (2.19e-3)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "prognostic favorable (4.04e-5)" "unprognostic (2.59e-3)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (5.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.89e-5)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" 15.6 9.7 0.0 172.4 0.1 43.2 64.1 0.1 0.2 27.9 0.1 325.8 430.3 5.7 0.2 52.2 5.5 44.1 15.1 0.0 0.0 6.2 14.5 72.1 450.4 1.1 0.0 10.6 8.5 0.3 1.1 0.1 0.2 6.3 209.5 0.0 116.6 6.3 0.2 0.7 219.6 3.4 0.0 305.9 285.6 1.4 0.2 82.1 9.8 0.1 461.2 204.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 1.3 0.0 5.4 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.6 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 331.7 0.2 0.1 0.2 224.0 0.0 0.1 0.9 0.1 0.1 0.1 0.2 32.3 0.0 0.1 0.1 0.2 0.0 0.0 1.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 11.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4593.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 IGLV5-37 ENSG00000211654 "Immunoglobulin lambda variable 5-37" A0A075B6J1 22 22427540-22428035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 24.7;intestine: 10.5;lymphoid tissue: 41.5;salivary gland: 11.5;stomach 1: 16.5" "Group enriched" "Detected in some" 4 "B-cells: 2.5;Late spermatids: 1.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 54 "memory B-cell: 6.1;naive B-cell: 7.0" "Lineage enriched" "Detected in single" 58 "B-cells: 7.0" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 14000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (4.69e-4)" "unprognostic (2.44e-2)" "unprognostic (5.68e-3)" "unprognostic (4.26e-1)" "prognostic favorable (4.71e-4)" "unprognostic (4.97e-2)" "unprognostic (3.56e-2)" "unprognostic (3.15e-1)" "unprognostic (5.34e-6)" "unprognostic (1.66e-1)" "unprognostic (4.32e-1)" "unprognostic (1.25e-1)" 0.7 0.0 0.0 9.5 0.0 1.0 3.2 0.0 0.0 1.8 0.0 10.5 10.1 0.2 0.0 4.2 0.9 24.7 1.1 0.0 0.0 0.9 0.7 3.6 4.5 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.6 8.0 0.1 11.5 0.0 0.0 0.0 8.8 0.2 0.0 22.7 16.5 1.2 0.0 8.4 0.6 0.0 41.5 3.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV5-45 ENSG00000211650 "Immunoglobulin lambda variable 5-45" A0A087WSX0 22 22375986-22376505 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 40.5;intestine: 43.5;lymphoid tissue: 97.5;salivary gland: 49.0" "Cell type enriched" "Detected in some" 116 "Plasma cells: 6697.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.2;naive B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 160000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (4.62e-4)" "unprognostic (6.18e-2)" "unprognostic (2.26e-2)" "unprognostic (1.48e-2)" "unprognostic (2.29e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.58e-3)" "unprognostic (2.77e-1)" "unprognostic (8.89e-2)" "unprognostic (1.06e-1)" "unprognostic (5.16e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (5.95e-6)" "unprognostic (6.14e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (8.36e-2)" 2.2 0.3 0.0 0.0 0.0 0.4 5.5 0.0 0.4 3.3 0.0 43.5 0.0 0.7 0.0 40.5 2.0 0.0 0.2 0.0 0.0 2.5 3.1 9.6 0.0 0.1 0.0 0.6 0.6 0.0 0.2 0.0 0.1 1.1 0.2 0.0 49.0 0.0 0.1 0.7 42.1 0.0 0.0 97.5 14.1 0.4 0.0 0.0 4.0 0.0 1.4 14.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 57.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6697.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 IGLV5-48 ENSG00000211647 "Immunoglobulin lambda variable 5-48 (non-functional)" A0A075B6I7 22 22352940-22353433 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.3;lymphoid tissue: 5.5;urinary bladder: 2.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 19.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 5.4;naive B-cell: 6.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.76e-3)" "unprognostic (1.91e-2)" "unprognostic (9.43e-2)" "unprognostic (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (1.74e-2)" "unprognostic (2.97e-1)" 0.0 0.0 0.0 0.9 0.0 1.3 0.9 0.0 0.6 0.4 0.0 3.3 3.3 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.1 0.1 0.3 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 1.3 0.2 0.0 5.5 0.7 0.0 0.0 2.5 0.1 0.0 5.3 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV5-52 ENSG00000211643 "Immunoglobulin lambda variable 5-52" A0A0A0MRZ9 22 22318727-22319226 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "B-cells: 1.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 11.7;naive B-cell: 10.3" "Lineage enriched" "Detected in many" 6 "B-cells: 11.7" "Low cell line specificity" "Detected in all" "Immunoglobulin genes" NA NA 1200000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "unprognostic (7.26e-2)" "unprognostic (7.05e-2)" "unprognostic (1.86e-2)" "unprognostic (4.66e-1)" "unprognostic (1.29e-1)" "unprognostic (7.61e-5)" "unprognostic (1.22e-1)" "unprognostic (1.89e-1)" "unprognostic (8.45e-2)" "unprognostic (1.51e-1)" "unprognostic (3.93e-2)" "unprognostic (2.25e-3)" "unprognostic (7.75e-2)" "unprognostic (3.51e-2)" "unprognostic (1.57e-1)" "unprognostic (5.46e-2)" 11.5 10.4 10.7 18.0 11.7 14.6 23.8 16.4 14.1 16.5 13.2 26.6 20.1 28.4 44.2 22.5 22.7 22.5 16.6 11.9 11.1 11.5 9.5 14.9 44.1 9.4 9.4 21.6 8.0 13.9 8.6 11.2 11.0 15.9 23.5 22.5 17.9 15.0 10.1 37.7 15.3 22.3 9.2 21.8 29.2 12.9 10.8 17.7 21.4 15.6 53.5 31.1 6.3 13.9 12.1 7.7 18.8 29.2 22.3 25.1 14.4 7.7 19.0 17.3 22.0 15.6 5.0 38.4 8.5 22.5 10.1 16.9 36.0 25.6 24.0 9.4 27.3 13.4 21.4 14.8 8.7 20.8 22.9 24.0 24.0 19.5 34.5 14.2 35.2 13.9 40.7 3.3 32.3 14.5 7.0 13.9 10.5 22.5 5.7 9.4 9.4 6.4 22.6 16.1 21.2 13.2 9.9 10.6 10.9 15.7 21.0 4.8 21.0 40.9 25.7 4.2 9.0 6.7 21.9 18.2 14.0 15.4 12.2 0.0 1.3 1.9 1.1 0.7 1.3 11.7 1.2 1.3 1.5 10.3 0.8 0.8 0.7 0.7 0.8 1.4 0.6 3.1 10.7 11.7 16.4 14.1 11.9 11.1 9.4 9.4 11.0 9.2 10.8 13.9 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1814.6;urinary bladder: 675.2" "Cell type enriched" "Detected in some" 72 "Plasma cells: 10791.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 353.9;naive B-cell: 292.4" "Lineage enriched" "Detected in many" 13 "B-cells: 353.9" "Cell line enhanced" "Detected in some" "Daudi: 148.0;RPMI-8226: 40.6;U-266/70: 21.6;U-698: 47.3" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" 15.6 9.1 0.0 220.8 0.1 191.7 215.5 0.0 0.6 82.3 0.4 485.0 351.3 19.1 4.4 171.4 38.2 75.8 39.2 0.1 0.0 10.7 26.8 97.0 237.6 0.6 0.1 20.3 7.7 17.8 1.1 0.4 0.5 17.2 318.8 0.0 249.6 12.7 0.3 3.2 174.3 11.5 0.1 276.6 437.6 15.9 0.1 139.7 15.3 0.0 1814.6 675.2 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.2 1.0 40.6 0.0 0.0 2.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.4 21.6 15.2 47.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.3 353.9 0.1 0.1 0.2 292.4 0.1 0.1 27.9 0.1 0.1 1.2 0.2 27.6 0.0 0.1 0.0 0.6 0.1 0.0 0.6 0.1 0.5 0.1 0.1 0.3 0.0 0.0 0.6 0.0 148.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 1.8 26.7 0.0 0.0 0.0 4.4 67.8 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10791.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 6.2 0.0 0.5 0.0 IGLV7-43 ENSG00000211652 "Immunoglobulin lambda variable 7-43" P04211 22 22395018-22395489 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 161.9;lymphoid tissue: 238.7;stomach 1: 115.9" "Cell type enriched" "Detected in some" 57 "Plasma cells: 1304.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 325 "memory B-cell: 132.0;naive B-cell: 54.2" "Lineage enriched" "Detected in single" 461 "B-cells: 132.0" "Cell line enhanced" "Detected in some" "Daudi: 1.9;RPMI-8226: 1.4;U-698: 1.5" HPA003182 Approved "Immunoglobulin genes" NA NA 130000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (6.49e-6)" "unprognostic (7.85e-3)" "prognostic favorable (7.00e-4)" "unprognostic (5.57e-2)" "unprognostic (3.62e-2)" "prognostic favorable (3.08e-5)" "unprognostic (7.63e-3)" "unprognostic (8.20e-2)" "unprognostic (2.42e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (6.29e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" 8.0 0.8 0.0 31.2 0.1 15.8 45.7 0.0 0.5 4.9 0.0 161.9 132.8 3.6 0.5 7.9 3.3 22.1 3.5 0.0 0.1 3.1 4.2 13.0 59.0 0.0 0.0 4.1 2.2 0.0 1.0 0.2 0.1 2.3 129.3 0.0 72.5 4.7 0.1 0.5 57.1 17.7 0.0 168.6 115.9 0.5 0.0 31.3 6.4 0.7 238.7 31.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 132.0 0.0 0.0 0.0 54.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.2 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1304.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.2 0.0 IGLV7-46 ENSG00000211649 "Immunoglobulin lambda variable 7-46" A0A075B6I9 22 22369614-22370087 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 400.6;lymphoid tissue: 459.1;stomach 1: 250.7;urinary bladder: 444.0" "Cell type enriched" "Detected in some" 180 "Plasma cells: 6758.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "hypothalamus: 1.6" "Group enriched" "Detected in some" 377 "memory B-cell: 183.6;naive B-cell: 82.3" "Lineage enriched" "Detected in single" 521 "B-cells: 183.6" "Cell line enhanced" "Detected in some" "Daudi: 8.0;RPMI-8226: 2.8;U-698: 6.6" HPA003182 Approved "Immunoglobulin genes" NA NA 270000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (3.34e-6)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (3.94e-3)" "unprognostic (4.25e-3)" "unprognostic (4.68e-3)" "unprognostic (1.74e-1)" "unprognostic (2.77e-2)" "unprognostic (7.47e-3)" "unprognostic (2.17e-1)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (2.99e-1)" "unprognostic (2.02e-1)" 15.1 3.8 0.0 59.8 0.3 44.2 171.7 0.1 0.9 4.1 0.1 400.6 162.4 4.4 0.0 43.7 3.0 56.0 5.2 0.0 1.6 5.7 7.7 44.9 82.2 0.4 0.0 9.0 6.2 0.1 0.8 0.1 0.2 2.5 298.6 0.0 107.2 5.2 0.5 0.8 133.1 12.1 0.1 248.1 250.7 0.7 0.2 57.3 8.7 0.0 459.1 444.0 3.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.3 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.3 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 183.6 0.1 0.0 0.1 82.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 15.2 0.0 0.3 0.1 0.9 0.0 1.6 0.4 0.0 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 12.8 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6758.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 IGLV8-61 ENSG00000211638 "Immunoglobulin lambda variable 8-61" A0A075B6I0 22 22098700-22099212 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 805.8;lymphoid tissue: 984.2" "Cell type enriched" "Detected in some" 4 "B-cells: 25.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.5" "Group enriched" "Detected in some" 630 "memory B-cell: 257.8;naive B-cell: 529.3" "Lineage enriched" "Detected in single" 848 "B-cells: 529.3" "Cell line enhanced" "Detected in some" "Daudi: 2.2;RPMI-8226: 3.6;SH-SY5Y: 1.8;U-266/70: 6.6" "Low region specificity" "Detected in all" "Immunoglobulin genes" NA NA 620000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.07e-3)" "unprognostic (2.73e-2)" "prognostic favorable (3.84e-4)" "unprognostic (1.07e-2)" "unprognostic (5.24e-2)" "unprognostic (1.04e-3)" "unprognostic (1.65e-1)" "unprognostic (1.75e-3)" "unprognostic (2.05e-1)" "unprognostic (2.11e-1)" "unprognostic (3.32e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (8.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-1)" 9.4 4.9 0.1 125.5 0.2 63.9 78.3 0.1 3.5 43.5 1.0 201.1 805.8 22.7 0.8 10.6 5.6 46.4 11.7 0.1 0.2 5.3 13.7 82.2 257.2 0.2 0.1 9.2 13.4 1.3 0.8 0.0 0.7 10.5 191.0 0.0 108.6 1.0 0.2 4.0 161.6 13.0 0.8 275.7 179.2 3.3 0.1 16.5 11.5 0.0 984.2 247.8 3.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.4 0.0 0.0 0.0 0.2 3.6 0.0 0.0 1.0 1.8 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.3 6.6 1.0 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.2 0.2 0.1 257.8 0.3 0.0 0.4 529.3 0.0 0.0 0.2 0.1 0.4 0.1 0.2 32.7 0.1 0.2 0.1 3.5 0.1 0.2 0.2 0.1 0.7 0.8 0.1 1.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 1.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV9-49 ENSG00000223350 "Immunoglobulin lambda variable 9-49" A0A0B4J1Y8 22 22343187-22343732 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 125.5;lymphoid tissue: 118.0" "Cell type enriched" "Detected in some" 20 "Plasma cells: 46.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 672 "memory B-cell: 70.3;naive B-cell: 88.1" "Lineage enriched" "Detected in single" 747 "B-cells: 88.1" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 43000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.04e-5)" "unprognostic (4.30e-3)" "unprognostic (1.83e-2)" "unprognostic (5.61e-2)" "prognostic favorable (2.00e-5)" "unprognostic (6.29e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.27e-2)" "unprognostic (2.81e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.12e-8)" "unprognostic (1.66e-1)" "unprognostic (3.07e-1)" "unprognostic (3.90e-2)" "unprognostic (7.16e-2)" 2.4 125.5 0.0 14.7 0.0 9.8 6.1 0.1 0.5 3.3 0.0 33.6 36.5 2.2 0.0 6.0 3.2 1.1 1.2 0.2 0.0 1.2 4.4 43.8 118.0 0.2 0.0 3.3 1.4 0.0 0.1 0.1 0.2 0.9 15.1 0.0 29.7 1.0 0.1 0.1 28.2 0.4 0.0 65.9 46.3 2.0 0.0 14.0 3.4 0.1 97.9 39.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.3 0.0 0.0 0.1 88.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.1 0.5 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGSF1 "IGCD1, IGDC1, INHBP, KIAA0364, MGC75490, PGSF2" ENSG00000147255 "Immunoglobulin superfamily member 1" Q8N6C5 X 131273506-131578899 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 73.4;pituitary gland: 167.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Astrocytes: 3.9;Bipolar cells: 14.0;Breast glandular cells: 5.0;Horizontal cells: 3.3;Melanocytes: 3.6;Skeletal myocytes: 7.2" "Cancer enriched" "Detected in many" 8 "thyroid cancer: 65.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 47.6;SH-SY5Y: 31.2" "Region enhanced" "Detected in all" "hypothalamus: 144.0" "Low region specificity" "Detected in all" "HPA012732, HPA035582" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 100000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA012732: AB_2732404, HPA035582: AB_2674687" "unprognostic (1.40e-3)" "unprognostic (1.79e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (4.25e-8)" "unprognostic (1.01e-1)" "unprognostic (2.40e-2)" "unprognostic (1.90e-3)" "unprognostic (2.52e-3)" "unprognostic (8.03e-3)" "unprognostic (9.36e-2)" "unprognostic (5.65e-2)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (5.96e-2)" "unprognostic (1.66e-1)" "unprognostic (2.35e-1)" "unprognostic (5.13e-2)" 1.9 12.5 9.7 0.8 10.0 0.1 2.8 9.7 9.7 3.3 4.8 0.9 0.4 1.2 2.4 1.6 2.5 1.2 12.1 7.5 73.4 0.7 1.5 0.3 0.4 10.0 21.6 1.1 2.6 0.8 167.8 0.7 24.0 4.0 0.4 6.4 2.4 5.7 2.0 1.4 0.6 3.1 7.4 0.3 1.0 12.2 32.4 0.6 4.5 5.1 0.9 0.4 0.9 8.4 0.4 0.6 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.0 0.0 0.0 0.1 1.8 0.0 0.0 6.0 0.4 0.0 3.0 47.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 4.1 2.8 0.0 0.0 0.0 0.1 0.1 0.2 3.4 31.2 0.0 0.2 0.0 4.1 0.6 0.0 0.0 0.5 0.8 0.0 4.1 1.2 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 10.0 9.7 9.7 7.5 73.4 10.0 21.6 24.0 7.4 32.4 8.4 0.2 3.2 0.6 3.9 0.2 0.0 0.5 0.0 1.2 14.0 5.0 1.7 2.3 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.3 1.5 0.0 0.1 0.0 0.7 0.7 0.3 0.0 3.3 0.4 0.0 0.0 0.0 0.8 1.1 0.0 0.2 3.6 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.4 0.0 0.3 0.0 0.8 0.0 0.7 0.0 7.2 0.3 0.1 0.4 0.0 0.4 0.3 0.1 0.0 0.0 0.3 IGSF10 "CMF608, FLJ25972" ENSG00000152580 "Immunoglobulin superfamily member 10" Q6WRI0 3 151425384-151458709 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.7" "Cell type enhanced" "Detected in many" "Early spermatids: 170.5;Horizontal cells: 60.6;Late spermatids: 34.1;Microglial cells: 61.8;Syncytiotrophoblasts: 30.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HeLa: 44.1;HL-60: 23.3;REH: 17.2;RPMI-8226: 55.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012655, HPA012921" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 540000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA012655: , HPA012921: AB_1851526" "unprognostic (1.78e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.47e-7)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (9.82e-2)" "unprognostic (8.84e-4)" "unprognostic (9.38e-3)" "unprognostic (1.96e-1)" "unprognostic (5.70e-2)" "unprognostic (2.04e-1)" "unprognostic (7.52e-4)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (4.59e-3)" "unprognostic (7.57e-4)" 3.9 4.0 1.4 0.9 0.7 0.6 6.1 0.3 1.0 0.5 3.2 1.3 0.5 1.4 1.6 2.9 4.3 9.7 4.3 2.8 1.1 0.2 0.3 8.6 1.4 0.1 1.0 17.7 0.7 1.3 1.7 0.7 0.3 0.1 1.3 0.2 5.2 0.2 0.1 1.9 1.2 1.5 0.0 0.9 0.7 0.9 3.6 1.3 1.5 0.5 2.5 2.2 0.3 0.3 0.0 0.1 0.3 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.1 0.0 0.4 0.0 0.0 0.3 0.3 7.5 44.1 0.0 1.6 23.3 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.2 0.1 55.1 0.1 0.1 1.0 0.0 5.9 0.0 0.0 0.2 0.0 0.2 0.0 0.1 1.1 0.0 0.0 2.4 0.0 0.0 0.2 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.7 0.3 1.0 2.8 1.1 0.1 1.0 0.3 0.0 3.6 0.3 2.0 0.0 0.5 1.0 0.6 2.4 1.2 0.5 2.8 15.8 0.6 0.9 1.6 2.8 6.3 1.8 4.2 21.7 2.7 0.2 0.0 0.1 170.5 11.4 4.0 0.9 6.0 3.4 2.4 1.3 2.9 20.4 0.5 0.5 0.0 0.0 0.0 0.1 1.3 60.6 2.8 0.7 4.1 0.8 3.2 34.1 6.8 2.9 3.6 61.8 1.1 25.6 0.0 0.5 0.7 0.4 0.1 1.2 0.3 0.7 0.0 0.3 12.5 2.4 0.0 0.5 2.2 10.7 7.9 0.8 2.4 30.9 0.6 2.5 0.1 0.2 IGSF11 "BT-IgSF, CT119, Igsf13, MGC35227, VSIG3" ENSG00000144847 "Immunoglobulin superfamily member 11" Q5DX21 3 118900557-119146068 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Growth regulation" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 46.3;ovary: 16.2;retina: 50.6;testis: 35.7" "Cell type enhanced" "Detected in many" "Astrocytes: 133.9;Early spermatids: 257.9;Inhibitory neurons: 139.1;Late spermatids: 334.0;Oligodendrocytes: 283.2" "Group enriched" "Detected in many" 9 "glioma: 9.2;melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 8.0;HEL: 5.9;SK-MEL-30: 35.1;U-266/70: 11.9;U-266/84: 15.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046377 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "Nucleoplasm, Cytosol" "HPA046377: AB_10966195" "unprognostic (2.05e-1)" "unprognostic (1.29e-1)" "unprognostic (1.62e-1)" "unprognostic (1.88e-1)" "unprognostic (1.17e-2)" "unprognostic (1.89e-3)" "unprognostic (2.51e-2)" "unprognostic (3.56e-2)" "unprognostic (3.91e-1)" "unprognostic (1.44e-1)" "unprognostic (2.20e-1)" "unprognostic (8.70e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-4)" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (7.57e-2)" 0.3 7.8 19.5 0.4 34.0 0.0 0.2 26.9 22.2 0.8 1.5 4.1 0.2 0.5 1.1 1.2 0.6 0.8 2.2 19.3 18.6 8.2 0.1 0.1 0.1 30.5 28.0 16.2 3.7 1.3 1.7 0.1 29.9 0.7 0.8 50.6 0.6 0.8 3.9 1.5 0.9 0.5 23.3 0.1 1.6 35.7 25.6 0.3 3.4 5.0 0.2 0.6 0.8 46.3 0.0 8.0 0.2 0.1 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 2.7 0.0 0.0 0.0 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.7 0.6 0.0 0.1 35.1 2.1 0.7 0.1 0.0 0.0 1.4 0.0 0.1 11.9 15.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 34.0 26.9 22.2 19.3 18.6 30.5 28.0 29.9 23.3 25.6 46.3 0.1 0.0 0.0 133.9 0.6 0.4 0.1 0.3 2.8 9.1 0.3 0.1 1.3 0.0 0.5 0.0 75.0 0.2 0.1 0.0 0.0 0.9 257.9 4.2 0.8 0.3 0.0 0.0 77.8 0.7 0.0 2.0 0.0 7.2 0.0 26.8 0.0 0.0 0.0 16.8 139.1 0.0 6.1 0.0 0.4 334.0 3.7 0.4 3.6 4.7 0.0 22.3 0.0 43.2 283.2 0.2 0.0 1.9 0.2 0.1 0.0 5.9 0.4 25.7 0.0 0.8 0.9 22.4 6.0 0.7 0.0 0.1 0.2 6.8 0.0 0.4 IGSF21 "MGC15730, RP11-121A23.1" ENSG00000117154 "Immunoglobin superfamily member 21" Q96ID5 1 18107798-18378483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.7" "Group enriched" "Detected in some" 4 "Bipolar cells: 177.8;Excitatory neurons: 82.2;Microglial cells: 74.9;Oligodendrocyte precursor cells: 141.3" "Group enriched" "Detected in many" 5 "breast cancer: 4.1;glioma: 8.6;prostate cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 23000 "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.50e-3)" "unprognostic (7.06e-2)" "unprognostic (3.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.66e-2)" "unprognostic (7.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.34e-2)" "unprognostic (2.33e-1)" "unprognostic (7.85e-4)" "unprognostic (3.76e-5)" "unprognostic (2.10e-1)" "unprognostic (1.23e-2)" "unprognostic (2.63e-2)" 2.2 4.8 29.6 0.4 35.8 0.4 3.0 41.4 51.7 1.7 9.2 1.0 0.0 1.0 0.4 0.9 1.0 0.8 1.0 37.4 17.6 1.1 0.4 1.5 0.2 26.9 23.4 0.6 1.9 10.4 1.6 1.4 27.0 3.8 0.3 9.4 1.1 1.1 0.3 0.8 0.4 0.3 21.6 13.0 0.6 0.8 24.5 0.8 0.6 0.4 0.7 3.9 1.1 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.6 35.8 41.4 51.7 37.4 17.6 26.9 23.4 27.0 21.6 24.5 33.5 0.1 0.0 0.0 3.6 0.6 0.3 0.2 0.0 0.0 177.8 9.2 2.7 0.6 1.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 5.9 0.0 0.0 1.8 3.0 0.0 82.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.7 28.9 0.1 0.0 23.6 4.0 12.8 0.6 12.8 0.0 74.9 0.0 6.3 0.0 141.3 2.4 0.1 1.3 0.0 0.0 0.9 0.0 0.0 0.0 13.0 6.6 4.5 0.2 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.2 IGSF8 "CD316, CD81P3, EWI2, PGRL" ENSG00000162729 "Immunoglobulin superfamily member 8" Q969P0 1 160091340-160098943 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 155.3" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011917, HPA075970" Approved Supported Vesicles NA NA 280000 "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA011917: AB_1851536, HPA075970: " "unprognostic (4.08e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.20e-1)" "unprognostic (1.71e-1)" "unprognostic (1.01e-3)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.31e-1)" "unprognostic (2.60e-2)" "unprognostic (2.35e-1)" "unprognostic (3.74e-3)" "unprognostic (1.75e-3)" 21.9 19.1 97.9 14.0 119.0 3.7 26.7 91.7 130.7 25.7 39.9 31.7 26.5 19.8 22.7 22.3 28.2 12.3 29.0 106.0 82.4 35.5 53.9 23.6 16.8 109.3 97.8 37.5 31.8 15.8 30.7 11.2 99.9 26.4 10.4 14.3 30.1 18.2 12.4 50.3 28.5 7.0 98.6 24.2 27.5 33.4 94.7 13.6 28.6 7.1 8.9 20.3 25.0 155.3 26.8 15.7 20.1 51.3 11.6 7.3 42.9 12.9 16.8 26.9 25.0 17.9 17.9 39.0 47.1 18.8 23.4 50.3 8.2 18.9 3.8 47.3 15.0 5.1 17.3 31.2 19.2 13.5 41.7 9.0 37.7 17.5 5.6 19.0 5.6 42.0 7.0 21.8 6.3 25.4 33.8 31.3 42.4 55.6 24.8 19.1 10.3 28.7 24.7 27.4 8.5 36.6 14.8 47.4 177.6 17.5 33.7 17.3 5.8 11.8 25.4 21.5 10.6 59.6 71.2 17.7 41.6 5.3 31.6 0.1 5.2 2.4 22.0 7.2 19.5 19.6 18.0 25.6 5.8 22.7 23.4 25.7 1.4 9.2 4.7 9.9 26.9 11.3 97.9 119.0 91.7 130.7 106.0 82.4 109.3 97.8 99.9 98.6 94.7 155.3 12.2 9.6 3.3 18.3 21.1 43.7 30.2 43.1 26.2 55.6 28.0 29.2 3.3 17.2 16.7 38.6 10.4 32.8 15.1 36.1 5.9 34.2 3.8 12.0 7.2 7.8 19.9 7.4 65.3 12.4 219.7 22.4 6.6 26.4 10.2 12.2 13.2 28.8 14.9 65.6 43.8 24.7 44.7 4.3 16.2 1.1 16.8 8.5 42.7 9.4 51.5 75.7 10.3 9.0 107.2 20.6 39.5 15.8 20.0 22.0 47.6 15.8 6.0 11.8 6.6 39.8 15.3 4.0 6.6 21.0 62.4 69.4 19.5 13.6 32.6 26.0 IGSF9 "IGSF9A, KIAA1355, Nrt1" ENSG00000085552 "Immunoglobulin superfamily member 9" Q9P2J2 1 159927039-159945613 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 32.8;retina: 34.8;skin 1: 23.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 93.8;Distal enterocytes: 83.5;Gastric mucus-secreting cells: 37.8;Rod photoreceptor cells: 145.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 24.9;HaCaT: 37.0;NTERA-2: 18.9;SCLC-21H: 32.9;SH-SY5Y: 16.8;T-47d: 18.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 2.9;cerebellum: 5.5" HPA037753 Uncertain "Intracellular and membrane" NA NA 140000 "Cluster 85: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA037753: AB_10672915" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (3.30e-2)" "unprognostic (6.06e-3)" "unprognostic (8.93e-3)" "unprognostic (1.37e-1)" "unprognostic (5.73e-2)" "unprognostic (2.05e-1)" "unprognostic (2.04e-2)" "unprognostic (2.15e-2)" "unprognostic (6.03e-3)" "unprognostic (2.87e-1)" "unprognostic (8.60e-2)" "unprognostic (1.42e-1)" "unprognostic (2.17e-2)" 4.4 0.0 0.1 0.6 0.4 0.2 2.1 0.1 0.3 2.6 0.0 9.8 7.4 0.8 2.0 10.0 4.6 0.4 0.9 0.1 0.5 1.4 32.8 0.5 0.0 0.2 0.2 0.7 1.7 1.6 0.6 0.2 0.2 6.0 4.3 34.8 5.7 3.5 0.0 23.3 9.6 0.3 0.0 0.2 12.8 5.0 0.5 1.8 1.4 0.0 0.7 1.8 6.3 0.2 8.6 0.0 3.3 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 12.1 4.2 0.0 0.3 0.1 0.0 37.0 1.8 5.1 0.0 0.0 0.1 0.6 0.6 0.0 0.0 0.0 0.0 0.0 15.9 0.3 0.5 0.0 0.0 1.5 0.4 0.0 0.0 15.9 0.3 0.0 18.9 14.4 4.0 0.0 0.0 1.5 0.0 11.6 32.9 16.8 1.1 14.3 0.0 3.3 18.6 0.0 0.0 0.0 6.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.3 0.1 0.5 0.2 0.2 0.2 0.0 0.5 0.2 0.1 0.0 0.0 0.3 0.1 13.4 3.7 8.2 6.8 11.6 5.6 6.2 1.8 10.0 3.4 0.0 93.8 1.3 0.0 83.5 0.0 4.5 19.8 7.8 0.9 1.3 8.3 0.0 0.0 33.8 3.2 1.2 37.8 13.7 0.0 1.9 0.4 19.6 0.2 1.7 0.0 7.9 4.1 0.3 2.8 3.4 0.3 0.4 0.0 0.0 0.0 5.1 0.0 0.0 0.1 29.0 12.5 0.0 0.1 2.1 24.1 0.1 3.4 145.8 0.0 0.2 0.4 0.6 1.8 6.4 12.5 0.7 0.2 0.7 7.4 1.7 IGSF9B "KIAA1030, LINC00947, LOC283174, MIR4697HG" ENSG00000080854 "Immunoglobulin superfamily member 9B" Q9UPX0 11 133896438-133956968 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.8;choroid plexus: 20.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 25.2;Inhibitory neurons: 11.6;Oligodendrocyte precursor cells: 30.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 38.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 10.0;SCLC-21H: 17.7;SH-SY5Y: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010802 Uncertain Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Cell Junctions" "HPA010802: AB_1079194" "unprognostic (9.04e-4)" "unprognostic (1.74e-2)" "unprognostic (7.52e-3)" "unprognostic (4.38e-4)" "unprognostic (8.35e-2)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" "unprognostic (6.17e-2)" "unprognostic (1.38e-1)" "unprognostic (8.10e-2)" "unprognostic (2.81e-1)" "unprognostic (2.99e-4)" "unprognostic (3.17e-1)" "unprognostic (2.19e-1)" "unprognostic (1.41e-1)" "unprognostic (9.14e-4)" "unprognostic (3.12e-3)" 1.0 1.4 9.4 1.4 3.8 0.2 0.8 38.8 30.7 2.2 20.2 4.7 0.5 4.8 3.0 2.8 4.6 1.2 6.7 8.3 0.0 0.4 0.0 0.8 0.7 0.0 0.9 1.0 0.9 0.7 2.6 0.6 1.1 2.6 1.3 9.3 0.8 4.1 4.7 2.3 1.3 4.5 0.0 0.9 1.9 3.3 0.0 0.5 2.5 3.5 0.7 2.6 1.6 0.0 0.0 0.6 1.2 0.0 0.0 0.0 4.2 0.1 0.0 0.1 0.0 0.1 2.6 1.6 0.7 0.6 0.3 3.7 3.9 0.0 0.1 2.8 3.1 0.0 0.0 0.0 0.1 1.0 5.1 0.1 0.0 0.0 0.5 0.5 0.0 4.7 0.0 0.0 0.0 1.9 0.5 0.4 2.5 10.0 0.0 0.0 0.0 0.0 0.9 0.0 17.7 11.1 0.1 0.2 0.0 3.7 1.8 0.0 0.0 1.2 1.3 1.0 0.9 0.0 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 9.4 3.8 38.8 30.7 8.3 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 3.4 0.1 0.2 0.0 2.9 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.4 0.0 0.0 0.9 0.0 0.0 25.2 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.5 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 30.7 0.2 0.1 0.1 0.4 0.0 0.2 0.0 0.1 0.0 0.9 0.0 0.2 0.6 0.0 0.3 0.1 4.8 0.0 0.6 0.1 0.2 0.1 IHH "BDA1, HHG2" ENSG00000163501 "Indian hedgehog signaling molecule" Q14623 2 219054424-219060921 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 14.0;intestine: 22.3;stomach 1: 15.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 31.5;Enteroendocrine cells: 49.2;Granulosa cells: 122.4;Intestinal goblet cells: 34.7;Proximal enterocytes: 18.8;Undifferentiated cells: 23.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.8;endometrial cancer: 30.9" "Region enriched" "Detected in single" 6 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 16.4;OE19: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 23000000 "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.63e-2)" "prognostic favorable (3.67e-6)" "unprognostic (4.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.28e-1)" "unprognostic (1.06e-1)" "unprognostic (5.86e-2)" "unprognostic (2.74e-1)" "unprognostic (6.31e-2)" "unprognostic (3.33e-3)" "unprognostic (1.81e-3)" "unprognostic (2.05e-1)" "unprognostic (5.31e-1)" "unprognostic (1.51e-2)" "unprognostic (2.91e-2)" 0.1 0.0 0.0 2.0 0.0 0.0 0.1 0.1 2.4 4.9 0.0 22.3 12.2 14.0 0.0 0.3 0.9 0.7 0.0 0.0 0.0 2.4 3.5 1.3 0.0 0.3 0.1 0.4 0.0 0.0 0.5 0.1 0.4 2.4 12.4 0.0 0.0 0.7 0.0 0.0 12.9 0.7 0.2 0.0 15.0 0.1 0.1 0.0 1.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 0.3 0.1 0.4 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.8 0.0 1.8 0.0 0.0 0.4 31.5 0.0 0.1 0.0 6.0 0.5 0.1 49.2 0.0 0.0 3.3 0.0 0.1 12.2 8.9 0.0 122.4 0.0 0.6 0.0 0.0 0.0 34.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 14.0 0.0 0.0 1.8 18.8 3.2 0.9 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 23.6 0.3 IKBIP "FLJ31051, IKIP" ENSG00000166130 "IKBKB interacting protein" Q70UQ0 12 98613405-98645113 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 28.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 28.1" "Cell line enhanced" "Detected in all" "BJ: 206.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038677, HPA038678, HPA061541" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA038677: AB_2676146, HPA038678: AB_10672723, HPA061541: AB_2684555" "unprognostic (3.06e-1)" "unprognostic (1.06e-3)" "unprognostic (2.13e-1)" "unprognostic (4.34e-2)" "unprognostic (1.94e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (4.00e-5)" "unprognostic (6.28e-3)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (7.37e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.60e-9)" "unprognostic (7.37e-2)" "unprognostic (1.66e-1)" "unprognostic (3.46e-1)" "unprognostic (3.16e-2)" 14.0 7.1 2.3 15.3 2.8 5.1 10.1 2.3 3.1 12.6 5.0 6.6 4.1 10.3 5.8 4.8 6.7 12.9 9.3 2.3 2.9 8.3 10.3 11.0 12.6 3.2 2.7 5.9 5.8 4.2 7.7 26.8 3.2 6.8 7.0 1.2 6.1 7.4 2.6 3.1 5.7 16.0 2.9 11.8 5.6 4.6 3.1 11.6 9.3 4.8 9.6 17.1 7.4 3.7 13.0 39.8 43.5 28.4 102.8 105.8 39.4 206.0 124.7 53.3 67.2 8.8 12.4 42.4 35.5 128.7 37.1 26.7 17.5 80.5 90.1 12.4 26.7 16.2 23.9 59.8 39.3 30.2 31.1 81.1 16.6 62.4 54.5 95.3 75.3 7.8 25.5 16.0 133.3 11.8 14.0 68.7 16.9 10.2 33.5 11.9 64.0 21.7 88.9 14.6 6.6 20.8 58.9 4.1 34.1 73.6 13.1 37.0 71.6 115.7 41.3 50.5 53.9 17.2 20.1 31.8 33.3 27.2 85.1 11.4 6.4 19.3 2.8 4.9 3.3 5.9 1.8 2.9 5.4 3.8 2.0 2.0 28.1 5.0 5.7 3.7 2.6 1.8 2.3 2.8 2.3 3.1 2.3 2.9 3.2 2.7 3.2 2.9 3.1 3.7 44.9 12.8 15.7 1.6 34.4 7.6 15.5 55.6 21.6 2.8 7.9 22.4 3.0 0.0 18.7 3.7 4.2 35.5 32.5 2.3 11.7 10.5 2.8 7.9 47.4 47.7 0.0 19.8 5.9 5.8 65.3 47.0 2.6 4.4 20.8 32.7 44.3 8.4 45.7 3.3 3.3 4.8 12.2 31.2 34.1 3.6 30.7 35.4 14.2 14.0 40.4 2.0 37.0 11.6 2.2 5.1 3.1 17.0 74.8 7.6 1.0 10.1 6.3 2.6 39.5 27.8 46.8 32.1 16.0 9.0 7.2 10.1 23.6 25.3 2.9 6.5 IL10 "CSIF, IL-10, IL10A, TGIF" ENSG00000136634 "Interleukin 10" P22301 1 206767602-206774541 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.7;lymphoid tissue: 7.7" "Group enriched" "Detected in some" 4 "Hofbauer cells: 28.3;Kupffer cells: 44.4;Langerhans cells: 35.5;Macrophages: 99.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in some" "thalamus: 3.5" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1;intermediate monocyte: 1.8" "Lineage enriched" "Detected in single" 6 "monocytes: 2.1" "Group enriched" "Detected in some" 11 "HMC-1: 14.6;U-266/70: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013120, HPA071391" Approved "Secreted to blood" NA NA 5670 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "CAB013120: , HPA071391: " "unprognostic (3.65e-2)" "unprognostic (1.14e-1)" "unprognostic (1.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.20e-1)" "unprognostic (2.63e-3)" "unprognostic (2.58e-1)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" "unprognostic (4.26e-1)" "unprognostic (8.01e-2)" "unprognostic (4.00e-1)" "unprognostic (4.66e-4)" "unprognostic (7.11e-2)" "unprognostic (1.93e-2)" "unprognostic (2.73e-1)" "unprognostic (1.96e-2)" 6.7 2.1 0.1 7.7 0.1 3.2 0.7 0.2 0.7 0.8 0.9 1.0 0.8 0.3 0.1 1.5 1.4 3.5 1.1 0.2 0.5 0.2 1.6 1.5 5.7 0.7 0.4 0.4 0.1 0.2 0.4 1.9 0.6 0.4 1.3 0.0 0.2 0.7 0.0 0.1 1.1 3.1 0.5 4.9 0.8 0.8 3.5 2.9 0.2 1.2 2.0 2.9 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.2 0.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.4 0.1 0.1 0.2 0.7 0.2 0.5 0.7 0.4 0.6 0.5 3.5 1.2 0.5 0.0 1.9 0.0 5.6 1.0 0.4 0.0 0.0 0.2 0.2 0.3 0.3 0.0 1.3 0.0 0.0 0.1 1.3 0.0 0.0 0.0 6.9 0.1 0.2 1.9 0.0 0.4 0.0 0.0 0.1 0.8 1.1 0.2 1.3 0.0 0.7 0.5 28.3 0.0 0.0 0.0 0.0 44.4 35.5 2.9 0.0 99.5 1.8 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.0 0.0 0.0 0.4 0.0 0.9 0.8 0.0 0.2 0.7 1.1 0.1 12.9 0.0 0.0 0.4 IL10RB "CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2" ENSG00000243646 "Interleukin 10 receptor subunit beta" Q08334 21 33266367-33310187 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 198.4;Extravillous trophoblasts: 164.9;Syncytiotrophoblasts: 315.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020670, HPA047550" Approved Approved Cytosol NA NA 1600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 43: THP-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "CAB020670: , HPA047550: AB_2680086" "unprognostic (8.43e-2)" "unprognostic (6.50e-2)" "unprognostic (5.88e-2)" "unprognostic (1.77e-1)" "unprognostic (1.48e-2)" "unprognostic (7.78e-2)" "unprognostic (1.97e-3)" "unprognostic (1.26e-1)" "unprognostic (5.69e-3)" "unprognostic (1.31e-1)" "unprognostic (1.19e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (5.62e-9)" "unprognostic (3.09e-1)" "unprognostic (2.76e-1)" "unprognostic (1.29e-2)" "unprognostic (1.05e-1)" 24.6 14.5 8.2 30.3 8.2 19.8 18.1 8.1 11.3 20.2 8.6 40.6 36.5 14.7 9.9 27.6 23.9 23.9 13.8 8.1 7.8 16.8 27.5 25.8 27.6 9.0 8.1 20.4 25.4 10.7 11.3 62.5 8.9 18.6 38.0 4.8 23.6 12.3 12.4 20.2 45.7 19.8 8.6 43.1 33.8 5.0 9.5 30.5 14.0 9.8 26.0 29.3 19.3 9.8 28.8 21.6 4.9 19.1 82.7 61.3 30.0 22.9 62.3 23.5 33.6 20.6 36.1 10.9 25.0 37.8 48.3 34.5 13.2 14.8 17.3 28.5 15.5 30.8 15.1 15.2 58.3 29.5 54.6 62.5 26.8 41.2 23.5 36.8 34.6 25.6 20.6 79.7 32.5 29.1 22.6 27.4 4.2 59.1 11.4 18.5 14.4 33.9 22.6 16.6 7.5 8.0 45.4 35.3 37.5 9.7 21.3 104.5 31.0 24.1 22.7 40.0 12.4 49.9 48.3 6.8 40.5 44.5 19.4 103.8 115.0 98.9 32.0 134.9 35.2 51.6 39.3 38.1 67.9 54.1 36.8 36.3 219.4 56.9 141.6 73.6 77.6 87.5 8.2 8.2 8.1 11.3 8.1 7.8 9.0 8.1 8.9 8.6 9.5 9.8 3.1 35.3 20.5 11.8 26.5 14.5 38.0 54.0 19.4 5.8 3.3 2.8 12.3 32.9 32.3 3.7 14.6 198.4 33.6 102.1 0.0 20.1 1.1 2.3 3.5 23.5 10.2 17.7 14.5 30.1 164.9 24.2 29.6 2.4 35.5 2.1 31.8 23.2 116.6 8.4 12.7 64.4 30.5 111.3 25.3 1.6 31.7 54.3 14.2 23.4 80.6 6.7 49.4 14.6 18.5 23.4 86.8 23.7 39.9 44.3 103.1 1.1 15.8 6.4 19.7 16.9 9.1 2.9 5.0 21.7 14.6 315.6 21.0 0.2 41.4 67.6 IL11 "AGIF, IL-11" ENSG00000095752 "Interleukin 11" P20809 19 55364382-55370463 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Pancreatic endocrine cells: 64.4;Smooth muscle cells: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 50.9;BJ hTERT+: 60.0;HBF TERT88: 39.0;hTEC/SVTERT24-B: 47.9;U-251 MG: 187.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 34800 "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (6.60e-3)" "unprognostic (7.23e-3)" "unprognostic (1.12e-1)" "unprognostic (3.18e-3)" "unprognostic (3.32e-3)" "unprognostic (6.33e-2)" "unprognostic (1.04e-2)" "unprognostic (7.84e-5)" "unprognostic (2.47e-1)" "unprognostic (2.52e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (4.83e-2)" "unprognostic (4.07e-8)" "unprognostic (1.23e-1)" "unprognostic (1.41e-1)" "unprognostic (3.82e-3)" "unprognostic (3.08e-2)" 0.7 0.2 1.1 3.6 0.6 0.9 0.3 2.2 1.3 0.3 0.3 1.0 0.2 2.9 0.3 1.2 0.2 2.8 0.5 0.6 2.6 4.7 0.2 1.2 0.0 3.3 2.6 0.4 0.3 0.0 4.4 1.1 2.6 2.7 0.1 0.5 0.6 0.6 0.0 1.5 0.5 0.3 1.3 0.3 3.7 1.7 2.9 0.3 0.1 0.0 0.1 2.4 0.5 0.5 2.3 1.4 0.5 0.9 0.0 0.0 0.5 50.9 60.0 26.6 35.2 1.2 1.3 0.7 2.5 5.1 14.4 3.0 0.3 1.4 39.0 2.4 1.7 0.2 4.3 3.8 3.1 0.0 0.3 0.3 1.5 47.9 0.3 12.4 0.0 0.2 0.4 1.8 3.4 1.5 0.1 0.4 1.2 2.1 4.2 0.2 16.9 0.3 0.4 0.5 2.9 2.0 6.8 1.2 1.4 6.8 0.8 0.3 0.7 16.1 20.0 0.2 187.4 1.0 2.5 0.4 33.9 0.4 8.9 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 1.1 0.6 2.2 1.3 0.6 2.6 3.3 2.6 2.6 1.3 2.9 0.5 0.3 0.0 0.5 0.3 0.3 3.2 0.6 4.4 1.2 1.7 0.4 1.8 1.1 0.0 0.6 0.0 0.0 0.2 0.0 0.3 0.0 12.7 0.9 3.6 1.8 0.5 0.0 0.0 0.6 2.8 1.2 12.7 0.0 5.6 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.1 0.0 0.0 0.3 0.0 0.0 0.6 1.8 0.0 1.0 0.2 0.0 0.0 0.1 64.4 1.2 1.5 0.0 1.3 0.0 0.2 0.4 0.6 0.0 0.4 51.8 0.4 1.6 0.5 0.6 0.3 0.2 0.0 0.3 0.9 IL11RA ENSG00000137070 "Interleukin 11 receptor subunit alpha" Q14626 9 34650702-34661902 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Craniosynostosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 57.8;Late spermatids: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 36.8;HSkMC: 38.2" "Low region specificity" "Detected in all" "HPA013162, CAB032830, HPA036652" Supported "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB032830: AB_2123745, HPA013162: AB_2668790, HPA036652: AB_2675229" "unprognostic (7.76e-2)" "unprognostic (7.63e-2)" "unprognostic (1.05e-1)" "unprognostic (6.76e-3)" "unprognostic (1.67e-1)" "unprognostic (1.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.52e-2)" "unprognostic (1.89e-2)" "unprognostic (4.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (2.14e-1)" "unprognostic (1.51e-1)" "unprognostic (2.93e-2)" "unprognostic (8.71e-2)" 26.6 14.8 20.0 15.5 22.9 13.7 30.2 23.9 23.8 44.6 17.2 58.0 21.7 32.9 12.2 16.3 36.8 19.5 66.4 20.6 20.4 21.9 50.7 22.6 32.0 21.4 21.5 38.0 12.9 29.2 21.8 10.3 20.4 30.3 11.4 18.7 26.1 15.7 30.0 61.3 37.9 19.6 20.8 33.3 26.0 18.3 21.6 16.9 48.0 28.5 21.1 32.2 34.1 22.9 2.5 5.5 11.7 11.7 16.5 28.9 5.5 13.8 19.1 8.8 11.9 2.0 4.6 2.6 3.7 36.8 3.3 5.0 3.4 5.0 3.5 23.8 9.2 7.9 23.4 1.0 8.4 2.7 4.3 38.2 6.1 4.9 1.7 11.9 5.6 16.4 3.3 5.4 11.3 1.6 3.6 18.6 2.5 2.0 3.7 5.6 2.3 2.7 2.9 2.5 3.4 12.3 1.7 3.7 5.3 6.1 10.1 10.2 5.2 4.1 10.0 3.2 0.0 3.7 2.6 1.0 10.9 3.1 20.1 2.1 1.0 0.0 1.4 1.4 2.1 0.8 2.7 2.2 1.3 1.0 2.5 1.8 0.3 1.0 0.3 0.5 1.7 1.7 20.0 22.9 23.9 23.8 20.6 20.4 21.4 21.5 20.4 20.8 21.6 22.9 15.8 3.2 14.3 26.8 2.6 17.5 5.8 3.6 6.2 19.6 6.4 25.1 37.9 1.5 3.6 3.7 14.6 11.3 5.1 3.7 0.0 1.9 18.3 0.7 4.4 15.2 9.1 0.8 4.3 0.7 4.1 42.7 3.1 1.3 0.0 57.8 17.5 32.1 4.6 23.5 9.0 5.0 0.0 3.5 19.6 97.2 11.1 3.6 32.0 4.7 2.6 15.2 6.2 5.0 7.3 0.3 4.3 5.7 2.4 2.9 7.0 2.4 1.4 9.0 0.0 32.9 8.9 4.6 21.6 1.4 14.1 12.4 6.0 12.2 5.2 1.7 IL12B "CLMF, CLMF2, IL-12B, NKSF, NKSF2" ENSG00000113302 "Interleukin 12B" P29460 5 159314780-159330487 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enriched" "Detected in some" 4 "monocytes: 6.7" "Cancer enriched" "Detected in single" 20 "testis cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA040970 Supported "Secreted to blood" NA NA 140000 "Cluster 11: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 3: Monocytes - Immune response regulation" "HPA040970: AB_10796234" "unprognostic (5.96e-5)" "unprognostic (4.59e-5)" "unprognostic (1.05e-1)" "unprognostic (3.40e-1)" "unprognostic (9.13e-4)" "unprognostic (6.89e-2)" "unprognostic (2.58e-4)" "unprognostic (6.69e-3)" "unprognostic (3.83e-2)" "unprognostic (4.50e-2)" "unprognostic (2.53e-1)" "unprognostic (7.15e-3)" "unprognostic (9.25e-2)" "unprognostic (1.87e-1)" "unprognostic (1.07e-1)" "unprognostic (1.02e-2)" 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.6 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.4 0.2 0.1 0.1 1.4 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6" "Cell type enhanced" "Detected in some" "dendritic cells: 35.1;Kupffer cells: 13.9;NK-cells: 69.0;Plasma cells: 15.3;T-cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 18.8;HDLM-2: 35.2;Karpas-707: 57.8;U-698: 15.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" 2.1 1.2 1.0 15.2 1.8 9.3 0.9 1.0 2.1 1.0 1.7 3.1 4.5 0.7 0.8 1.6 0.8 3.5 0.7 1.1 1.1 0.9 2.2 5.8 24.6 2.5 1.5 0.6 0.5 1.3 0.5 1.6 2.3 0.8 2.9 0.5 1.7 0.6 0.7 1.6 7.0 1.9 1.1 16.2 4.1 0.8 2.3 6.6 0.7 0.2 14.1 4.0 0.5 3.7 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.1 0.5 1.0 0.3 2.2 18.8 0.1 0.2 0.7 0.3 0.0 0.0 0.0 35.2 0.2 2.2 0.6 0.3 1.0 0.9 3.1 0.1 0.0 0.5 0.0 0.2 0.1 5.1 0.3 57.8 0.0 0.2 9.7 0.3 0.1 0.1 0.0 6.7 0.1 0.8 0.0 0.1 0.4 0.0 0.2 0.2 0.2 0.1 0.4 9.7 0.4 0.5 0.4 0.2 0.2 6.6 11.0 15.2 0.6 12.1 1.1 8.5 12.5 9.2 50.9 34.7 64.0 11.5 34.8 41.7 14.7 9.1 19.3 34.0 14.7 40.9 34.0 8.1 53.0 24.3 1.0 1.8 1.0 2.1 1.1 1.1 2.5 1.5 2.3 1.1 2.3 3.7 0.5 0.0 3.0 0.3 9.6 0.3 2.1 0.1 0.6 0.0 0.3 0.5 1.0 1.5 0.6 0.0 0.0 0.2 35.1 0.1 0.0 0.0 0.5 0.5 0.2 0.5 0.0 5.2 0.8 0.0 0.8 0.7 3.1 0.7 4.5 0.0 0.4 0.1 6.4 0.0 0.4 0.0 0.0 13.9 4.0 0.0 0.0 11.7 0.0 3.7 11.9 0.0 69.0 0.0 2.6 0.1 0.0 0.0 15.3 0.5 0.4 0.2 0.2 0.0 0.0 0.7 0.3 0.4 0.1 0.0 0.9 0.1 31.5 0.0 0.2 1.3 IL12RB2 ENSG00000081985 "Interleukin 12 receptor subunit beta 2" Q99665 1 67307364-67398724 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.5;placenta: 7.0" "Cell type enhanced" "Detected in some" "dendritic cells: 8.4;Excitatory neurons: 22.5;Inhibitory neurons: 16.6;T-cells: 12.8" "Group enriched" "Detected in many" 4 "cervical cancer: 1.8;head and neck cancer: 2.5;melanoma: 5.6;renal cancer: 1.7" "Region enhanced" "Detected in many" "hippocampal formation: 4.5" "Immune cell enhanced" "Detected in many" "NK-cell: 21.3" "Group enriched" "Detected in many" 35 "NK-cells: 21.3;T-cells: 6.0" "Group enriched" "Detected in some" 9 "HMC-1: 4.6;SCLC-21H: 6.8;SK-MEL-30: 18.4;THP-1: 13.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "Low region specificity" "Detected in all" HPA024168 Uncertain Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA024168: AB_1851629" "unprognostic (1.32e-1)" "unprognostic (1.54e-3)" "unprognostic (2.09e-1)" "unprognostic (2.68e-2)" "unprognostic (2.82e-2)" "unprognostic (1.09e-3)" "unprognostic (2.37e-2)" "unprognostic (3.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.38e-2)" "unprognostic (1.39e-1)" "unprognostic (3.60e-2)" "unprognostic (1.08e-3)" "unprognostic (1.82e-1)" "unprognostic (4.69e-2)" "unprognostic (7.11e-3)" "unprognostic (1.90e-1)" 1.9 0.3 1.2 1.2 1.6 0.8 0.4 0.0 2.3 0.6 0.0 0.4 0.3 0.2 0.3 0.8 0.1 0.5 0.2 4.5 0.0 0.3 0.8 0.4 1.8 0.0 0.7 0.2 2.6 0.8 0.0 7.0 0.0 0.1 0.4 0.1 1.3 0.7 3.5 1.4 0.4 0.4 0.0 1.4 0.3 1.0 0.3 1.0 0.1 0.7 0.9 0.7 0.2 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 1.2 0.6 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.3 0.0 0.1 18.4 0.0 0.0 13.4 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 6.0 0.0 3.2 0.0 1.6 1.0 0.0 0.0 0.0 0.1 0.3 21.3 0.0 0.0 3.9 1.2 1.2 1.6 0.0 2.3 4.5 0.0 0.0 0.7 0.0 0.0 0.3 0.7 0.2 0.0 2.3 1.0 0.6 0.5 0.2 0.1 0.6 0.0 0.1 0.3 0.7 0.0 0.7 0.0 0.0 0.0 8.4 0.0 0.0 0.0 1.5 0.3 0.3 0.1 0.0 0.8 22.5 0.0 0.0 0.9 2.6 0.7 0.0 1.5 0.0 0.0 3.8 0.0 16.6 0.0 0.0 0.8 0.9 0.9 0.0 0.5 1.8 2.8 0.0 0.0 4.1 1.0 1.6 0.2 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.0 0.6 0.0 12.8 0.0 0.0 0.1 IL13 "ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600" ENSG00000169194 "Interleukin 13" P35225 5 132656263-132661110 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 24.3" "Cell type enhanced" "Detected in some" "Early spermatids: 96.7;Late spermatids: 200.7;Spermatocytes: 44.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 187 "HDLM-2: 41.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA042421 Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 40000 "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042421: AB_10795504" "unprognostic (2.17e-1)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.92e-1)" "unprognostic (5.21e-3)" "unprognostic (1.79e-1)" "unprognostic (2.69e-1)" "unprognostic (5.20e-1)" "unprognostic (7.10e-2)" "unprognostic (3.61e-3)" "unprognostic (3.34e-1)" "unprognostic (5.97e-4)" "unprognostic (4.70e-2)" "unprognostic (2.05e-1)" "unprognostic (7.39e-2)" "unprognostic (1.38e-1)" 0.3 0.0 0.1 0.6 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.2 0.1 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 96.7 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 200.7 2.8 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.5 44.4 1.2 0.0 0.6 0.0 14.7 0.0 0.0 0.0 IL13RA1 "CD213a1, IL-13Ra, NR4" ENSG00000131724 "Interleukin 13 receptor subunit alpha 1" P78552 X 118727133-118794535 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 10.9;eosinophil: 12.2;myeloid DC: 17.2;neutrophil: 29.2" "Group enriched" "Detected in many" 7 "dendritic cells: 17.2;granulocytes: 29.2;monocytes: 10.9" "Cell line enhanced" "Detected in many" "HDLM-2: 181.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001587 Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 17000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles Nucleoplasm "HPA001587: AB_1079133" "unprognostic (5.14e-3)" "unprognostic (4.72e-2)" "unprognostic (7.12e-2)" "unprognostic (7.75e-2)" "unprognostic (8.81e-3)" "unprognostic (3.82e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-1)" "unprognostic (2.44e-1)" "unprognostic (1.90e-1)" "unprognostic (8.21e-2)" "prognostic unfavorable (1.19e-8)" "unprognostic (1.88e-2)" "unprognostic (2.37e-2)" "unprognostic (2.82e-2)" "unprognostic (5.08e-2)" 51.9 34.3 15.9 40.3 16.2 7.1 41.5 18.1 17.3 27.1 20.4 52.1 48.5 31.9 26.2 53.5 35.8 39.3 20.2 14.6 22.3 33.7 120.3 48.9 25.4 26.0 20.3 37.5 22.3 22.2 15.4 32.8 24.6 22.5 61.6 25.6 34.7 27.1 31.4 20.6 60.8 40.6 22.2 29.9 35.8 16.6 19.6 16.0 29.8 55.9 34.5 31.6 27.4 24.6 31.6 37.2 17.4 48.0 39.0 113.5 33.1 63.3 86.2 29.2 37.6 21.8 55.0 0.1 111.4 86.6 84.8 29.1 19.0 26.6 32.3 181.0 16.5 5.1 30.9 55.8 23.4 0.6 13.0 104.1 23.5 40.0 48.8 87.9 61.8 0.0 16.6 3.3 41.9 44.8 0.1 8.5 16.1 57.8 38.6 0.1 43.3 0.2 43.6 32.9 6.5 6.0 102.3 35.5 24.7 22.8 22.8 28.9 79.3 56.7 26.7 99.7 50.5 0.7 16.8 0.3 125.6 16.1 24.6 0.2 10.9 12.2 0.0 2.7 0.1 2.9 0.0 0.0 17.2 2.5 0.0 0.0 29.2 0.1 1.1 2.9 0.1 2.9 15.9 16.2 18.1 17.3 14.6 22.3 26.0 20.3 24.6 22.2 19.6 24.6 36.0 70.5 48.5 1.0 20.2 17.2 37.1 17.2 18.2 2.1 32.4 26.3 11.5 37.1 46.0 29.5 16.7 8.1 2.8 61.9 9.8 36.1 38.1 25.8 34.0 58.8 93.2 4.8 0.3 98.3 31.9 38.7 38.7 27.3 0.0 13.6 78.9 149.0 41.2 0.0 2.0 138.4 16.2 124.8 140.6 7.3 24.2 120.4 21.4 73.1 199.7 43.7 2.1 0.0 6.9 87.9 27.0 18.8 1.3 42.3 70.8 25.2 49.7 11.2 32.9 14.4 26.2 7.5 28.9 37.2 12.1 9.4 2.7 7.1 29.5 30.8 IL15RA "CD215, IL-15RA" ENSG00000134470 "Interleukin 15 receptor subunit alpha" Q13261 10 5943639-5978187 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 39.1;Exocrine glandular cells: 55.2;Fibroblasts: 37.6;Hepatic stellate cells: 36.0;monocytes: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 70.8;EFO-21: 41.3;HDLM-2: 78.5;HHSteC: 42.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 8 "cerebellum: 7.1" CAB026215 Approved "Secreted to blood" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "CAB026215: " "unprognostic (2.86e-2)" "unprognostic (8.41e-2)" "unprognostic (6.13e-2)" "unprognostic (4.45e-2)" "unprognostic (7.87e-2)" "unprognostic (5.49e-2)" "prognostic unfavorable (2.67e-6)" "unprognostic (5.09e-3)" "unprognostic (1.82e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.18e-3)" "prognostic unfavorable (1.27e-12)" "unprognostic (4.43e-2)" "unprognostic (4.69e-2)" "unprognostic (4.08e-2)" "unprognostic (5.75e-2)" 19.3 7.5 3.3 20.4 3.7 11.7 18.3 3.0 4.6 21.5 3.6 12.3 16.2 15.0 4.6 11.5 18.8 23.2 17.8 2.8 4.4 14.1 19.5 44.5 21.3 5.7 3.9 3.7 11.5 2.2 4.6 16.1 4.6 10.4 10.9 0.3 8.0 5.3 7.1 11.2 15.7 12.1 4.8 15.1 16.3 3.2 4.6 5.7 12.1 10.2 11.6 25.7 12.7 3.5 16.8 2.4 0.0 0.7 21.5 4.9 4.3 8.6 18.4 10.7 11.4 0.3 70.8 1.9 41.3 16.0 6.0 15.6 2.0 12.1 2.4 78.5 3.5 2.0 4.9 1.2 42.7 0.9 0.6 4.1 4.2 6.0 0.2 4.4 29.1 1.3 20.5 23.5 0.3 9.3 3.6 8.9 0.4 6.7 6.8 10.0 0.0 13.4 2.8 1.3 0.1 0.1 12.9 1.4 0.6 0.2 6.1 8.0 10.8 0.5 1.3 30.1 11.2 20.5 6.2 0.4 4.9 12.4 0.7 10.2 26.0 6.6 18.9 32.8 29.1 10.8 14.7 19.7 7.1 6.4 6.1 11.0 7.5 11.5 21.0 0.1 17.7 12.8 3.3 3.7 3.0 4.6 2.8 4.4 5.7 3.9 4.6 4.8 4.6 3.5 25.2 6.4 5.0 1.3 6.0 5.7 5.7 9.9 4.6 0.0 4.4 3.0 5.8 22.8 3.3 0.0 0.0 0.6 4.2 5.8 0.0 39.1 1.7 5.1 23.0 21.0 5.4 19.8 3.3 55.2 1.6 37.6 9.7 6.7 3.8 0.1 36.0 8.7 6.6 0.0 0.9 6.8 2.0 14.7 5.5 2.1 5.0 7.3 3.6 12.2 55.0 0.0 4.1 1.0 0.3 35.5 13.3 0.7 22.2 20.1 9.3 0.1 3.4 0.0 0.0 7.1 6.4 0.2 0.4 4.6 6.5 0.1 7.8 0.0 9.3 6.8 IL17A "CTLA8, IL-17, IL-17A, IL17" ENSG00000112115 "Interleukin 17A" Q16552 6 52186375-52190638 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enriched" "Detected in single" 14 "T-cells: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "Karpas-707: 2.7;U-266/84: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA052258 Uncertain "Secreted to blood" NA NA 9920 "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA052258: " "unprognostic (5.55e-1)" "unprognostic (2.18e-4)" "unprognostic (3.05e-4)" "unprognostic (1.41e-2)" "unprognostic (2.22e-2)" 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.2 IL17B "IL-17B, IL-20, MGC138900, MGC138901, NIRF, ZCYTO7" ENSG00000127743 "Interleukin 17B" Q9UHF5 5 149371324-149404202 "Cancer-related genes, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 44.8;Peritubular cells: 13.2;Sertoli cells: 26.3;Smooth muscle cells: 7.6;Theca cells: 9.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "basophil: 1.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.2" "Cell line enhanced" "Detected in some" "HEL: 1.3;Karpas-707: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA042441 Uncertain "Secreted to blood" NA NA 75000 "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 36: HEL - Hemostasis" "Cluster 48: Smooth muscle cells - ECM organization" "HPA042441: AB_10797014" "unprognostic (2.83e-4)" "unprognostic (2.71e-2)" "unprognostic (4.90e-3)" "unprognostic (9.22e-2)" "unprognostic (7.43e-2)" "unprognostic (5.03e-2)" "unprognostic (9.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.80e-1)" "unprognostic (6.54e-2)" "unprognostic (9.30e-3)" "unprognostic (3.22e-1)" "unprognostic (6.98e-8)" "unprognostic (2.66e-1)" "unprognostic (1.53e-1)" "unprognostic (6.47e-2)" "unprognostic (1.10e-1)" 1.4 2.2 0.0 1.0 0.0 0.2 2.9 0.5 0.1 3.2 0.0 3.1 0.3 4.3 0.0 1.5 1.1 0.4 1.1 0.0 0.0 0.7 0.0 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.1 2.4 0.1 0.4 2.8 2.1 0.3 0.9 1.3 2.2 0.0 0.6 0.8 3.7 0.0 0.0 0.1 0.2 0.0 1.4 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.8 44.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.3 0.0 0.0 0.1 0.2 0.6 1.3 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 1.0 1.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 26.3 0.6 7.6 0.1 0.1 0.0 0.3 0.0 0.0 9.9 0.0 0.1 IL17C "CX2, IL-17C, IL-21, MGC126884, MGC138401" ENSG00000124391 "Interleukin 17C" Q9P0M4 16 88638572-88640468 "Predicted secreted proteins" "Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 2.1;urinary bladder: 1.7" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 210.7;Club cells: 191.2;Ionocytes: 52.9" "Cancer enhanced" "Detected in some" "stomach cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA065051 Supported "Secreted to blood" NA NA 30500 "Cluster 71: Testis - DNA repair" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA065051: AB_2685413" "unprognostic (1.60e-1)" "unprognostic (1.69e-1)" "unprognostic (7.31e-2)" "unprognostic (4.45e-1)" "unprognostic (5.58e-2)" "unprognostic (2.93e-2)" "unprognostic (3.50e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-2)" "unprognostic (3.46e-1)" "unprognostic (1.89e-2)" "unprognostic (3.04e-3)" "unprognostic (2.73e-2)" "unprognostic (7.91e-2)" "unprognostic (3.56e-3)" "unprognostic (8.37e-3)" 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 210.7 0.0 0.0 0.1 0.0 0.1 4.3 191.2 0.0 0.0 0.0 1.6 0.7 0.0 0.9 0.0 0.9 0.2 0.1 0.0 0.0 0.0 4.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.3 52.9 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.3 0.3 0.1 21.8 0.0 0.0 0.0 1.3 0.4 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.4 IL17D "FLJ30846, IL-17D, IL-27, IL27" ENSG00000172458 "Interleukin 17D" Q8TAD2 13 20702127-20723098 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.8;skeletal muscle: 131.1" "Cell type enhanced" "Detected in many" "Astrocytes: 64.0;Early spermatids: 19.3;Excitatory neurons: 17.5;Late spermatids: 35.0;Muller glia cells: 20.2;Oligodendrocyte precursor cells: 20.6" "Group enriched" "Detected in many" 9 "glioma: 10.8;melanoma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 25000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (2.23e-1)" "unprognostic (4.26e-2)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "unprognostic (1.37e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.35e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (7.93e-2)" "unprognostic (5.97e-2)" 8.4 5.7 71.9 1.6 79.7 0.4 6.4 68.7 58.7 15.2 21.6 5.6 9.4 6.5 1.1 8.9 5.0 5.1 11.6 66.0 70.9 2.6 0.8 6.2 1.2 79.1 62.2 9.3 5.9 0.4 8.9 1.6 61.8 5.5 0.5 10.6 4.3 1.6 131.1 5.4 5.7 1.2 79.6 0.9 4.4 3.9 68.2 0.2 7.6 24.5 0.3 5.4 9.9 79.8 16.5 2.2 3.5 7.6 8.1 4.6 18.3 4.5 1.1 0.4 0.8 7.6 8.7 11.0 0.8 0.4 5.3 8.5 1.5 0.1 0.2 4.0 12.2 0.8 0.7 9.1 1.0 12.2 2.4 6.3 0.1 0.6 0.0 6.9 5.0 15.3 4.5 0.0 3.0 15.9 13.6 10.0 10.7 19.2 2.6 17.8 8.6 1.3 0.2 14.1 20.7 6.7 2.6 3.8 18.3 6.1 9.6 10.4 27.1 1.7 3.0 1.4 5.7 2.0 1.7 2.9 4.0 5.7 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.9 79.7 68.7 58.7 66.0 70.9 79.1 62.2 61.8 79.6 68.2 79.8 0.7 0.0 0.0 64.0 0.2 2.4 0.3 0.0 1.2 1.2 0.4 0.4 1.0 0.0 0.0 0.0 0.0 1.1 0.3 0.7 0.0 0.1 19.3 0.2 1.6 0.6 0.0 0.4 17.5 0.2 7.4 7.6 0.0 0.7 0.0 0.9 1.4 0.0 0.4 0.0 12.2 0.1 0.0 0.3 1.9 35.0 11.5 0.2 8.8 2.8 0.0 20.2 0.0 20.6 12.5 0.2 0.1 1.2 0.0 0.5 0.2 0.2 0.0 4.9 0.0 9.4 2.0 8.6 0.6 0.0 2.0 1.1 0.3 0.1 0.3 0.2 IL17F "IL-17F, ML-1, ML1" ENSG00000112116 "Interleukin 17F" Q96PD4 6 52236681-52244500 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 30000 "Cluster 14: B-cells - Humoral immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.40e-1)" "unprognostic (1.20e-1)" "unprognostic (3.02e-1)" "unprognostic (2.52e-1)" 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IL17RA "CD217, CDw217, hIL-17R, IL-17RA, IL17R" ENSG00000177663 "Interleukin 17 receptor A" Q96F46 22 17084954-17115694 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.9;Kupffer cells: 81.4;Macrophages: 61.4;monocytes: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HL-60: 59.9;NB-4: 52.5;THP-1: 74.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB024996 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 62000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB024996: " "unprognostic (1.92e-1)" "unprognostic (3.15e-1)" "unprognostic (1.65e-2)" "unprognostic (9.83e-2)" "unprognostic (7.66e-2)" "unprognostic (5.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-2)" "unprognostic (8.52e-2)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (1.96e-2)" "prognostic favorable (8.35e-4)" "unprognostic (2.16e-2)" "unprognostic (1.27e-1)" "unprognostic (6.51e-3)" 9.1 5.6 5.5 9.6 11.3 31.8 6.9 5.7 7.5 5.4 6.8 4.7 3.8 5.4 5.0 5.2 6.0 3.6 4.6 6.3 5.5 3.7 5.7 10.0 6.9 9.8 7.3 4.5 5.2 3.9 3.8 3.5 8.9 5.0 3.4 1.5 5.2 2.8 1.8 6.9 6.2 5.3 7.7 16.6 5.6 2.0 7.7 15.4 4.2 2.6 5.6 4.6 4.7 9.6 7.9 4.5 4.1 5.1 8.0 4.6 5.1 11.5 7.4 5.3 6.8 4.4 5.1 7.1 4.6 11.6 6.9 12.4 5.6 5.4 3.7 11.6 6.6 0.0 2.6 2.8 9.2 59.9 17.8 6.8 7.9 4.7 3.7 5.2 5.7 5.6 3.0 7.3 5.5 6.7 7.2 52.5 2.2 10.1 4.3 1.6 0.8 1.3 5.1 5.8 2.8 0.1 8.0 6.7 5.7 4.6 5.3 74.7 15.9 4.1 5.8 6.1 4.3 5.8 3.4 3.3 6.0 28.3 4.5 8.5 7.4 7.2 1.1 3.4 0.9 0.5 1.5 1.2 3.9 0.4 2.4 1.8 16.5 1.5 3.5 1.8 1.0 2.6 5.5 11.3 5.7 7.5 6.3 5.5 9.8 7.3 8.9 7.7 7.7 9.6 14.0 12.8 14.1 2.9 13.8 8.8 6.6 10.2 10.8 3.9 7.2 5.8 6.1 10.0 8.6 5.5 8.4 6.1 18.7 23.6 0.0 8.7 4.0 7.2 8.1 13.7 13.2 9.2 8.3 12.6 11.9 13.6 29.0 9.7 7.6 58.9 17.5 11.1 34.0 3.3 6.4 13.9 6.1 81.4 16.2 2.1 9.0 61.4 8.8 41.2 114.2 4.3 28.8 12.5 11.4 12.2 12.4 4.5 10.3 9.1 14.7 3.4 8.0 2.9 13.1 10.4 10.0 3.0 13.4 9.0 6.8 6.4 25.4 8.1 12.4 9.6 IL17RC IL17-RL ENSG00000163702 "Interleukin 17 receptor C" Q8NAC3 3 9917074-9933630 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.7;myeloid DC: 2.1" "Group enriched" "Detected in many" 18 "dendritic cells: 2.1;monocytes: 1.7" "Cell line enhanced" "Detected in many" "ASC diff: 71.2;ASC TERT1: 43.6;HSkMC: 40.7;T-47d: 41.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019885, CAB026255" Approved "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "CAB026255: , HPA019885: AB_1851664" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.38e-4)" "unprognostic (2.58e-2)" "unprognostic (1.45e-3)" "unprognostic (8.60e-2)" "unprognostic (7.11e-2)" "unprognostic (1.38e-2)" "unprognostic (5.27e-2)" "unprognostic (4.30e-2)" "unprognostic (5.98e-2)" "unprognostic (9.35e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.48e-1)" "unprognostic (2.83e-1)" 17.5 32.2 5.5 4.2 5.5 3.8 18.8 5.0 7.1 16.6 6.0 21.4 15.0 15.0 4.9 23.6 14.8 7.4 19.9 5.7 6.6 15.7 63.7 9.2 1.8 6.2 5.9 12.9 15.3 17.0 27.9 2.9 4.9 31.3 4.7 1.1 23.7 12.6 16.9 32.2 15.5 6.9 6.6 5.9 16.8 1.7 7.0 1.9 13.9 15.7 2.4 17.9 19.4 5.0 7.3 4.6 1.5 4.5 71.2 43.6 10.8 10.0 23.4 12.3 19.5 1.6 19.9 0.0 11.8 15.8 8.7 5.1 2.0 10.7 4.1 4.7 6.0 1.9 13.6 6.6 22.0 0.1 0.0 40.7 8.7 14.9 3.3 5.7 10.6 0.0 0.8 9.1 9.8 11.3 0.2 0.4 0.9 2.6 31.4 4.5 5.1 2.6 9.1 4.1 4.0 6.4 6.1 13.7 10.8 0.4 41.2 0.8 8.9 13.4 6.4 5.9 6.7 0.1 0.3 0.0 21.0 0.9 9.8 0.0 1.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 5.5 5.5 5.0 7.1 5.7 6.6 6.2 5.9 4.9 6.6 7.0 5.0 10.1 0.0 0.5 18.9 2.0 10.8 18.6 11.2 12.5 2.1 30.2 24.1 3.4 18.6 11.7 1.8 0.0 5.8 2.6 22.4 3.9 15.1 0.5 8.0 8.7 7.8 14.4 6.5 3.8 21.1 4.7 15.7 15.8 10.0 0.0 14.0 11.4 43.9 11.0 1.7 4.8 25.3 16.2 6.0 7.8 1.4 19.0 6.0 14.2 4.7 3.4 25.5 1.0 7.1 0.9 13.2 29.8 17.0 1.7 25.7 53.2 17.7 6.9 1.6 19.7 12.8 12.4 0.8 0.5 13.3 19.9 2.9 2.1 11.9 20.0 16.6 IL17RE FLJ23658 ENSG00000163701 "Interleukin 17 receptor E" Q8NFR9 3 9902612-9916402 "Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.8;skin 1: 31.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 92.6;Gastric mucus-secreting cells: 58.1;Intestinal goblet cells: 52.1;Paneth cells: 37.7;Proximal enterocytes: 74.4;Undifferentiated cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 38.5;hTCEpi: 16.5;T-47d: 19.4" "Region enhanced" "Detected in single" "cerebellum: 1.5" HPA019011 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA019011: AB_1851667" "unprognostic (1.08e-2)" "unprognostic (7.58e-2)" "unprognostic (2.06e-1)" "unprognostic (1.43e-3)" "unprognostic (1.09e-1)" "unprognostic (9.81e-2)" "unprognostic (1.50e-1)" "unprognostic (8.43e-2)" "unprognostic (6.69e-2)" "unprognostic (6.31e-2)" "unprognostic (3.55e-3)" "unprognostic (4.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-2)" 6.1 0.4 0.5 1.4 1.6 0.0 5.9 2.2 1.0 4.5 0.3 16.6 20.8 1.8 2.7 7.5 2.5 6.8 1.2 0.4 0.9 2.8 0.8 8.1 0.4 1.5 0.4 0.6 9.7 4.2 1.6 1.1 2.3 4.8 13.8 0.1 6.3 3.3 0.4 31.0 20.4 1.4 0.4 1.0 16.7 0.2 0.3 2.8 3.2 0.2 1.7 1.7 6.6 0.4 2.6 0.3 0.0 0.1 15.5 38.5 11.3 1.0 1.4 0.3 0.9 2.9 2.3 0.0 0.6 2.7 0.0 7.1 0.0 6.2 0.1 0.1 0.1 0.8 0.2 6.8 0.4 0.0 3.2 2.4 16.5 0.0 0.1 0.0 0.1 2.5 0.1 0.0 0.7 3.1 0.4 11.3 0.1 8.1 0.8 0.0 0.0 0.1 2.8 3.2 0.6 0.2 0.0 6.5 0.0 0.3 19.4 0.3 1.5 0.1 0.0 0.3 0.2 0.2 0.1 0.0 0.4 6.5 0.2 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 2.2 1.0 0.4 0.9 1.5 0.4 2.3 0.4 0.3 0.4 3.4 6.4 1.1 3.3 1.0 14.5 11.9 2.3 14.2 3.0 8.4 8.3 0.9 15.7 2.0 16.5 0.0 4.3 0.8 92.6 7.9 2.7 0.2 1.4 2.0 1.3 33.6 9.0 2.4 4.8 1.8 4.9 58.1 1.3 0.0 1.2 1.8 15.4 2.6 1.7 1.9 52.1 2.0 2.2 3.5 0.4 2.1 1.6 5.4 0.0 1.0 4.7 2.1 2.0 0.6 2.5 37.7 3.4 0.8 6.1 74.4 8.0 1.0 1.0 19.7 1.8 7.2 1.6 2.3 11.8 14.8 0.8 2.8 1.0 40.8 4.6 IL18BP IL18BPa ENSG00000137496 "Interleukin 18 binding protein" O95998 11 71998613-72005715 "Disease related genes, Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "Adipocytes: 14.0;Exocrine glandular cells: 13.6;Kupffer cells: 14.2;Langerhans cells: 12.9;Macrophages: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025980, HPA041061" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 3070000 16000000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "CAB025980: , HPA041061: AB_2677280" "unprognostic (2.66e-3)" "unprognostic (2.04e-3)" "unprognostic (9.14e-3)" "unprognostic (1.70e-2)" "unprognostic (5.58e-3)" "unprognostic (7.75e-2)" "unprognostic (1.41e-1)" "unprognostic (6.20e-2)" "unprognostic (1.19e-2)" "unprognostic (1.75e-3)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.93e-6)" "unprognostic (1.19e-1)" "unprognostic (4.14e-2)" "unprognostic (6.76e-2)" "unprognostic (1.93e-2)" 14.4 18.4 6.0 25.0 6.3 7.9 13.6 7.1 9.1 12.5 4.9 12.7 8.3 10.4 3.5 6.4 10.1 8.1 10.9 5.8 8.3 24.9 15.0 31.1 26.2 8.7 7.8 11.1 8.4 2.5 10.7 17.1 9.0 16.5 11.0 3.8 8.9 4.2 5.0 7.4 17.2 13.5 6.1 49.2 10.2 6.1 8.5 6.5 12.6 2.4 11.9 12.2 8.5 7.3 1.7 2.3 5.1 2.9 1.0 1.6 5.9 3.3 1.8 3.0 4.0 11.7 2.4 1.2 2.2 1.3 3.4 4.0 2.5 2.4 2.0 2.5 3.8 4.5 7.6 3.7 1.3 2.4 12.3 2.4 2.3 2.4 1.2 3.5 6.3 7.9 7.4 2.0 1.8 3.2 3.8 5.7 3.6 1.9 2.2 6.1 5.4 1.9 2.1 4.4 2.8 5.3 3.0 4.2 3.7 4.8 3.6 2.7 13.6 4.2 3.5 5.1 1.9 3.3 1.8 2.1 1.7 11.5 2.3 7.0 20.2 56.1 52.5 72.9 23.9 31.9 27.5 31.6 36.9 20.2 22.5 32.5 8.6 5.2 60.9 53.7 15.1 39.8 6.0 6.3 7.1 9.1 5.8 8.3 8.7 7.8 9.0 6.1 8.5 7.3 14.0 6.4 3.3 0.7 8.0 2.0 0.4 0.7 0.0 3.3 2.1 1.9 1.8 1.5 1.0 0.0 10.4 1.0 7.2 0.5 0.0 3.0 0.0 1.1 1.9 11.1 0.0 0.8 0.7 13.6 1.4 3.4 1.1 1.8 7.6 2.2 10.4 0.5 11.2 3.3 0.5 0.8 0.0 14.2 12.9 0.0 0.9 15.4 0.0 1.0 4.6 1.1 7.2 0.5 0.0 5.4 0.2 0.7 2.3 1.0 1.1 1.9 1.8 3.7 0.0 1.8 1.6 0.7 0.5 0.6 2.0 0.8 6.4 1.6 0.8 0.2 IL19 "IL-10C, IL-19, MDA1, NG.1, ZMDA1" ENSG00000142224 "Interleukin 19" Q9UHD0 1 206770764-206842979 "Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 20.0;salivary gland: 6.9" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 11.3;Breast glandular cells: 3.2;Club cells: 9.6;Endometrial ciliated cells: 2.9;Glandular and luminal cells: 5.2;Ionocytes: 4.1" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "BJ hTERT+: 9.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 172000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (6.21e-2)" "unprognostic (3.84e-2)" "unprognostic (3.55e-1)" "unprognostic (2.17e-2)" "unprognostic (2.48e-5)" "unprognostic (1.07e-1)" "unprognostic (8.72e-3)" "unprognostic (8.42e-2)" "unprognostic (2.04e-3)" "unprognostic (9.17e-2)" "unprognostic (7.20e-2)" "unprognostic (4.91e-2)" "unprognostic (2.78e-1)" 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 20.0 0.0 0.1 0.0 0.3 0.0 1.8 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.1 6.9 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.2 0.3 0.2 0.1 0.0 0.4 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.0 11.3 0.0 0.0 3.2 0.0 0.1 0.0 9.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.9 0.7 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 4.1 0.0 1.2 0.2 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 127.1;Endometrial stromal cells: 280.2;Glandular and luminal cells: 315.4;Hepatic stellate cells: 146.7;Langerhans cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 624.9;ASC TERT1: 276.8;HHSteC: 196.3;HSkMC: 770.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1400000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" 137.3 68.0 7.1 69.5 8.3 18.0 77.5 7.5 11.0 161.1 16.2 39.3 20.7 33.5 105.2 32.1 52.0 92.0 58.3 7.6 9.0 45.7 75.5 115.5 17.1 16.2 8.4 31.1 43.3 126.7 13.1 120.8 8.9 66.7 30.5 8.5 34.2 47.4 18.6 40.1 40.3 49.9 10.0 41.0 43.9 20.6 14.9 21.7 52.5 16.0 19.7 87.4 40.2 7.7 2.0 12.8 0.3 10.8 624.9 276.8 4.4 27.4 123.8 19.2 28.7 5.7 3.4 0.0 19.8 55.0 33.9 5.5 0.2 2.2 16.1 55.5 0.1 0.7 2.9 31.3 196.3 0.1 0.3 770.6 2.3 21.7 5.2 8.4 8.7 0.0 3.5 1.1 28.1 5.6 0.0 1.2 0.7 5.6 0.9 0.3 2.0 0.4 18.3 13.4 0.1 0.3 12.5 7.7 0.0 3.6 11.1 0.8 0.3 54.7 3.6 92.1 2.2 0.1 0.0 0.1 21.3 0.6 3.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.6 0.0 7.1 8.3 7.5 11.0 7.6 9.0 16.2 8.4 8.9 10.0 14.9 7.7 99.3 25.6 73.2 1.3 1.8 31.1 46.8 8.2 5.2 0.1 19.4 13.7 5.2 28.6 68.6 5.5 0.0 6.1 2.5 0.7 3.9 31.7 7.0 127.1 280.2 103.6 1.2 14.3 0.5 21.8 82.8 79.1 2.0 315.4 1.3 0.3 146.7 47.1 5.4 0.0 3.0 0.5 10.2 12.0 188.2 12.6 28.0 26.0 19.6 23.4 7.0 9.0 0.0 0.5 0.5 12.0 0.3 1.5 1.8 65.9 0.0 8.3 28.6 1.0 6.6 37.7 34.3 1.3 1.2 4.5 38.6 23.9 8.5 4.0 0.8 23.6 IL1R2 "CD121b, IL1RB" ENSG00000115590 "Interleukin 1 receptor type 2" P27930 2 101991960-102028544 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 90.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 495.7;Kupffer cells: 207.9;Langerhans cells: 1083.3;Macrophages: 210.8;Pancreatic endocrine cells: 211.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.1" "Group enriched" "Detected in some" 6 "cerebral cortex: 6.4;pons: 1.9" "Immune cell enriched" "Detected in some" 26 "neutrophil: 377.5" "Lineage enriched" "Detected in many" 26 "granulocytes: 377.5" "Cell line enriched" "Detected in some" 8 "HDLM-2: 469.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA027597, HPA027598" Uncertain "Secreted to blood" NA NA 7130000 27000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA027597: AB_10600768, HPA027598: AB_10601229" "unprognostic (3.54e-2)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (3.83e-2)" "unprognostic (6.59e-2)" "unprognostic (1.42e-1)" "unprognostic (6.36e-2)" "unprognostic (4.82e-3)" "unprognostic (1.62e-2)" "unprognostic (7.15e-2)" "unprognostic (8.20e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.58e-12)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "unprognostic (1.77e-1)" "unprognostic (6.62e-2)" 19.7 5.9 0.2 35.5 0.7 52.8 3.7 0.3 6.4 10.3 1.9 29.7 0.8 2.5 3.5 41.2 17.7 5.3 4.0 0.2 0.5 16.0 11.6 30.8 3.3 0.5 0.4 1.2 3.7 0.3 0.8 20.1 1.9 2.3 43.7 0.1 7.9 2.2 1.2 30.7 4.6 3.4 0.3 90.1 33.0 0.5 0.7 7.4 1.9 2.9 38.5 6.2 20.5 0.3 7.3 0.9 0.0 0.0 0.9 1.2 0.8 0.0 0.2 0.0 0.1 7.7 0.2 0.1 14.7 0.0 0.3 2.9 0.0 0.5 0.0 469.8 0.4 0.1 0.1 4.0 2.5 0.0 0.0 9.9 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 60.4 0.0 0.0 0.0 0.0 24.0 1.7 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.4 0.0 1.1 0.4 7.2 0.2 0.0 0.3 0.0 0.5 0.2 0.0 0.1 4.3 0.0 0.0 2.3 0.0 0.0 0.9 0.0 14.5 0.0 0.0 0.0 377.5 0.2 0.1 0.2 5.9 1.5 0.2 0.7 0.3 6.4 0.2 0.5 0.5 0.4 1.9 0.3 0.7 0.3 1.2 6.4 1.1 0.0 1.7 147.9 13.5 2.0 495.7 0.0 0.5 0.4 0.6 10.0 0.3 1.8 0.0 1.2 1.2 23.8 5.9 15.0 2.8 14.5 1.5 4.4 6.7 2.7 0.0 8.3 36.3 6.1 18.3 8.0 2.5 0.0 3.6 16.2 5.8 0.0 0.0 117.4 0.0 207.9 1083.3 4.0 0.3 210.8 32.0 0.0 3.5 0.0 0.0 0.0 0.0 211.0 26.8 0.0 1.6 20.4 0.0 0.7 2.2 0.0 6.6 0.7 3.8 0.7 2.2 38.1 84.0 27.8 2.7 0.4 26.8 14.4 IL1RAP "C3orf13, IL-1RAcP, IL1R3" ENSG00000196083 "Interleukin 1 receptor accessory protein" Q9NPH3 3 190514051-190659750 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 225.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 109.2;Hepatocytes: 295.8;Oligodendrocyte precursor cells: 298.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "eosinophil: 23.8;neutrophil: 95.0" "Lineage enriched" "Detected in many" 15 "granulocytes: 95.0" "Cell line enriched" "Detected in many" 4 "SK-MEL-30: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035293 Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 350000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "HPA035293: AB_10671511" "unprognostic (6.48e-2)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (8.84e-3)" "unprognostic (2.35e-2)" "unprognostic (6.60e-2)" "unprognostic (2.62e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.16e-7)" "unprognostic (4.02e-3)" "unprognostic (9.06e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (6.29e-4)" 6.2 2.9 4.0 11.4 1.1 20.3 4.3 0.0 8.7 4.4 0.5 2.2 1.8 4.0 2.6 13.1 5.4 12.1 3.9 4.6 3.1 3.3 225.8 8.2 2.7 2.4 3.7 3.0 3.9 1.5 1.2 37.0 3.3 3.9 2.2 2.4 5.2 3.4 1.3 11.9 2.2 6.4 1.5 5.4 4.5 1.3 5.5 4.6 4.0 2.1 4.8 9.4 5.5 3.3 13.3 3.0 5.5 0.8 9.5 7.7 10.0 5.8 11.9 13.4 13.2 5.8 29.3 2.2 59.2 16.4 31.1 34.1 3.0 57.6 18.7 2.5 3.6 2.9 5.3 14.5 19.6 20.2 9.5 10.3 23.1 19.7 59.2 27.8 6.0 5.9 0.4 0.2 6.4 6.5 1.7 9.4 8.5 6.0 6.0 9.5 8.2 4.8 5.3 14.8 1.0 0.0 26.3 15.0 247.1 5.2 9.6 14.6 7.9 10.3 10.4 32.1 26.6 5.0 0.2 0.5 17.2 18.0 60.9 11.7 3.8 23.8 1.8 4.3 3.3 2.1 2.1 2.3 3.8 2.1 2.0 1.3 95.0 0.3 6.3 0.6 2.1 1.4 4.0 1.1 0.0 8.7 4.6 3.1 2.4 3.7 3.3 1.5 5.5 3.3 3.5 0.0 14.7 6.5 6.8 44.7 16.5 45.8 68.9 6.5 2.5 4.7 5.5 40.0 22.8 3.7 8.4 8.5 3.6 1.8 0.0 7.7 4.4 8.6 3.8 8.0 5.4 4.4 44.3 7.5 109.2 7.3 7.1 12.3 7.6 0.7 7.5 295.8 7.8 0.0 63.3 1.4 4.1 33.7 17.7 0.6 4.4 28.8 8.8 53.4 5.0 1.0 6.2 298.6 1.5 19.7 0.8 2.6 5.3 11.5 0.7 1.1 8.7 0.6 0.0 18.0 5.1 0.1 0.6 30.9 37.2 24.2 5.2 1.4 1.1 14.3 IL1RL1 "DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1" ENSG00000115602 "Interleukin 1 receptor like 1" Q01638 2 102311502-102352037 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 126.4;lung: 162.0;placenta: 199.8" "Cell type enriched" "Detected in many" 9 "granulocytes: 501.5" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 64 "basophil: 38.3;eosinophil: 29.3" "Lineage enriched" "Detected in single" 72 "granulocytes: 38.3" "Group enriched" "Detected in some" 6 "HHSteC: 245.1;HMC-1: 373.7;HUVEC TERT2: 185.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007406, HPA007917" Uncertain Supported "Plasma membrane,Focal adhesion sites,Cytosol" "Secreted to blood" NA NA 19100000 3100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA007406: AB_1079128, HPA007917: AB_1079129" "unprognostic (7.25e-2)" "unprognostic (9.72e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (5.28e-2)" "unprognostic (1.98e-2)" "unprognostic (3.25e-3)" "unprognostic (2.07e-1)" "unprognostic (2.77e-1)" "unprognostic (4.50e-2)" "unprognostic (8.58e-2)" "unprognostic (9.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-2)" "unprognostic (1.60e-2)" "unprognostic (1.17e-1)" "unprognostic (4.60e-3)" 22.3 30.3 7.5 3.1 9.8 0.7 14.7 7.8 11.0 3.6 12.2 5.2 1.7 2.5 0.6 4.4 2.6 14.7 24.7 7.2 8.2 126.4 16.0 162.0 0.7 7.6 7.7 1.1 4.8 0.8 5.7 199.8 7.7 4.9 3.4 2.8 1.8 4.6 2.5 4.3 8.0 3.7 8.0 1.4 25.1 0.5 9.6 1.3 4.1 0.7 0.8 6.5 3.9 8.9 0.9 0.2 0.7 0.1 15.1 0.6 0.3 0.5 0.7 0.4 0.6 0.3 0.5 0.5 0.7 0.2 0.2 1.4 0.2 6.3 0.4 0.2 0.1 45.7 0.8 0.8 245.1 1.9 373.7 5.1 1.5 6.2 40.0 0.6 185.5 0.2 0.9 0.8 0.7 0.4 0.6 8.7 0.3 0.4 0.7 0.3 0.2 0.2 1.0 0.3 0.6 0.4 0.5 0.3 0.2 0.4 0.3 0.1 15.4 0.5 0.5 3.5 0.5 0.1 0.3 0.4 0.7 0.6 0.5 38.3 0.0 29.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 7.5 9.8 7.8 11.0 7.2 8.2 7.6 7.7 7.7 8.0 9.6 8.9 22.6 9.6 13.1 0.0 0.1 8.5 20.3 0.4 0.0 0.0 0.3 0.1 2.7 0.0 7.7 1.8 0.0 0.0 3.3 0.1 0.0 3.2 0.4 1.1 14.8 49.7 0.0 1.3 0.2 0.5 0.1 54.5 0.0 2.5 501.5 0.0 26.4 0.7 0.0 0.0 0.2 0.0 0.0 0.3 19.1 1.3 0.9 3.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 37.2 0.0 0.0 3.2 15.7 0.0 0.0 6.6 0.3 39.5 1.5 37.7 0.0 0.0 0.0 5.1 0.0 31.5 0.0 0.0 16.4 IL1RL2 "IL1R-rp2, IL1RRP2" ENSG00000115598 "Interleukin 1 receptor like 2" Q9HB29 2 102187006-102240002 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 12.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 5.6;Excitatory neurons: 9.7;Glandular and luminal cells: 8.4;Langerhans cells: 7.1;Suprabasal keratinocytes: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 8.1;ASC TERT1: 5.1;HaCaT: 3.8;HSkMC: 4.4;hTCEpi: 2.3" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "hippocampal formation: 1.0" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "unprognostic (6.70e-2)" "unprognostic (1.17e-1)" "unprognostic (6.57e-2)" "unprognostic (2.76e-4)" "unprognostic (3.42e-3)" "unprognostic (2.60e-1)" "unprognostic (3.13e-3)" "unprognostic (6.79e-2)" "unprognostic (9.10e-3)" "unprognostic (9.17e-2)" "unprognostic (4.61e-2)" "unprognostic (2.38e-1)" "unprognostic (1.05e-2)" "unprognostic (8.33e-3)" "unprognostic (3.80e-1)" "unprognostic (1.47e-1)" "unprognostic (7.65e-2)" 1.0 1.5 0.5 0.5 0.6 0.3 2.6 0.1 0.9 1.5 0.0 0.9 0.1 0.4 1.4 5.8 2.3 2.3 0.5 0.7 1.0 4.3 2.9 0.5 0.0 0.8 0.5 0.3 0.5 2.6 0.3 0.3 0.8 0.9 1.1 0.0 2.2 2.3 0.4 12.3 0.3 0.3 0.1 0.1 1.6 0.1 0.9 0.3 2.4 0.7 1.0 1.0 2.5 0.3 8.1 0.0 0.0 0.0 1.5 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 3.8 0.0 0.6 0.4 0.4 0.0 0.0 1.1 0.0 1.5 0.0 0.0 4.4 2.3 1.2 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.1 0.9 0.7 1.0 0.8 0.5 0.8 0.1 0.9 0.3 1.1 0.0 1.1 0.3 0.0 5.6 2.7 0.7 3.4 0.0 2.1 2.4 0.3 1.5 0.4 1.8 0.0 0.1 0.2 0.5 3.9 0.2 0.3 3.8 2.4 0.9 1.2 0.0 9.7 0.2 0.2 1.4 0.5 8.4 0.0 0.0 0.0 1.3 0.6 0.0 1.1 1.1 0.0 2.8 7.1 0.2 1.5 4.2 0.0 1.9 0.6 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 2.0 0.0 0.4 0.1 0.0 0.0 1.8 1.7 0.0 0.0 5.2 5.5 0.1 0.2 0.6 0.7 1.8 IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113107214-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1969.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 184.4;Hofbauer cells: 306.0;Langerhans cells: 292.6;Squamous epithelial cells: 469.7;Suprabasal keratinocytes: 336.6;Urothelial cells: 464.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 63.8;myeloid DC: 61.7;neutrophil: 240.2" "Group enriched" "Detected in many" 694 "dendritic cells: 61.7;granulocytes: 240.2;monocytes: 63.8" "Cell line enhanced" "Detected in some" "A-431: 59.1;HaCaT: 112.3;RT4: 106.6;THP-1: 27.3" "Not detected" "Not detected" "HPA001482, CAB009633" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" NA NA 291000 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Centrosome, Cytosol" "CAB009633: AB_2125576, HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" 13.0 2.1 0.2 46.7 0.4 233.3 9.0 0.4 1.3 278.1 1.1 4.4 10.7 2.5 2.9 1969.7 2.1 17.0 2.5 0.3 0.3 1.6 248.5 20.1 1.4 0.4 0.5 0.9 1.8 2.0 2.3 21.1 0.8 2.4 4.0 0.0 287.1 7.5 0.8 128.6 8.8 3.9 0.8 14.7 45.5 6.4 1.3 5.2 6.4 3.0 311.7 185.7 465.0 0.6 59.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.2 0.0 0.6 0.2 0.2 0.0 1.1 112.3 0.0 3.3 0.0 0.1 0.0 0.3 0.0 17.3 0.0 0.3 20.3 0.0 14.3 0.7 0.0 2.0 0.0 0.0 0.3 0.3 0.0 0.5 0.1 14.7 0.0 13.2 0.0 0.0 0.1 0.1 0.0 106.6 0.0 0.0 0.1 0.8 0.1 0.0 0.0 27.3 0.3 1.4 0.0 0.7 0.1 0.6 0.1 0.2 10.3 10.5 0.3 0.0 63.8 1.9 0.0 27.7 0.0 0.1 0.0 0.0 61.7 0.1 0.1 0.1 240.2 0.0 13.7 0.8 0.1 19.8 0.2 0.4 0.4 1.3 0.3 0.3 0.4 0.5 0.8 0.8 1.3 0.6 1.7 6.4 7.7 0.0 4.1 184.4 81.3 151.8 56.9 0.0 4.9 3.4 0.4 11.5 60.6 3.7 0.0 1.8 0.2 6.5 0.0 27.5 34.8 7.8 1.4 4.8 0.0 3.2 0.3 28.0 2.9 11.0 44.4 23.6 10.1 0.0 3.3 53.0 306.0 0.0 0.2 1.1 6.1 39.8 292.6 93.3 0.6 111.1 24.9 0.0 22.6 0.0 2.1 0.5 0.2 149.9 0.1 0.4 2.8 58.4 9.3 0.2 20.2 0.0 0.0 0.3 3.8 0.8 0.2 469.7 336.6 4.5 3.3 0.0 3.2 464.9 IL2 "IL-2, TCGF" ENSG00000109471 "Interleukin 2" P60568 4 122451470-122456725 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Cytokine, Growth factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Melanocytes: 3.6;T-cells: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB010310 Uncertain "Secreted to blood" NA NA 20300 "Cluster 7: Non-specific - Mitochondria" "CAB010310: AB_649346" "unprognostic (8.87e-5)" "unprognostic (6.13e-3)" "unprognostic (1.38e-3)" "unprognostic (9.79e-3)" "unprognostic (2.56e-2)" "unprognostic (7.32e-2)" "unprognostic (2.06e-5)" "unprognostic (5.21e-3)" "unprognostic (8.01e-2)" 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 13.4 0.0 0.0 0.0 IL20 "IL-20, IL10D, ZCYTO10" ENSG00000162891 "Interleukin 20" Q9NYY1 1 206865623-206869223 "Predicted secreted proteins" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.8;skin 1: 1.1" "Cell type enriched" "Detected in some" 4 "Basal keratinocytes: 69.6" "Cancer enhanced" "Detected in some" "breast cancer: 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SiHa: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" CAB025802 Uncertain "Secreted to blood" NA NA 109000 "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "CAB025802: " "unprognostic (3.08e-2)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (1.16e-2)" "unprognostic (6.45e-2)" "unprognostic (3.36e-2)" "unprognostic (1.01e-1)" "unprognostic (3.46e-1)" "unprognostic (1.60e-1)" "unprognostic (3.38e-2)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" 1.8 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.6 6.6 15.1 0.0 0.0 9.4 3.7 0.1 0.0 2.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 2.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.3 0.0 9.9 0.0 0.1 0.0 0.1 7.3 IL20RA "IL-20R1, ZCYTOR7" ENSG00000016402 "Interleukin 20 receptor subunit alpha" Q9UHF4 6 136999971-137045180 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 26.4;skin 1: 37.7" "Cell type enhanced" "Detected in many" "Breast glandular cells: 58.6;Endometrial ciliated cells: 110.4;Glandular and luminal cells: 69.8;Muller glia cells: 54.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.5;HaCaT: 6.9;OE19: 10.1;RT4: 11.5;SH-SY5Y: 10.8;T-47d: 10.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB024990, HPA042281" Approved Approved Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" Cytosol "CAB024990: , HPA042281: AB_10806235" "unprognostic (3.75e-2)" "unprognostic (8.23e-2)" "unprognostic (1.96e-2)" "prognostic favorable (1.43e-6)" "unprognostic (1.57e-2)" "prognostic favorable (2.29e-5)" "unprognostic (9.87e-3)" "unprognostic (1.64e-1)" "unprognostic (2.43e-1)" "unprognostic (3.78e-1)" "unprognostic (8.03e-3)" "unprognostic (2.18e-1)" "unprognostic (1.85e-6)" "unprognostic (9.38e-2)" "unprognostic (1.88e-1)" "unprognostic (3.09e-3)" "unprognostic (1.64e-3)" 0.9 8.8 3.0 0.7 3.5 0.1 26.4 3.9 2.7 17.1 4.9 4.6 3.1 5.9 4.4 7.0 17.3 4.9 2.4 2.4 3.9 0.4 0.4 5.9 0.0 3.7 4.7 4.9 7.9 2.8 1.6 0.2 4.0 8.6 4.6 4.9 9.7 5.5 0.7 37.7 1.3 3.0 4.3 0.0 6.2 2.0 4.2 1.6 1.1 2.4 2.6 6.0 11.9 3.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 9.5 0.0 0.1 1.5 0.1 6.9 1.2 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.3 10.1 1.4 0.0 0.4 0.0 0.0 11.5 0.7 10.8 0.5 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.5 3.9 2.7 2.4 3.9 3.7 4.7 4.0 4.3 4.2 3.5 1.4 3.2 26.1 6.2 0.0 21.9 12.0 12.7 6.2 3.5 58.6 39.5 4.6 37.1 22.3 3.7 0.0 2.7 0.5 12.1 0.0 15.3 0.8 110.4 8.0 1.1 7.3 0.0 0.1 0.7 10.6 5.0 19.9 69.8 2.5 0.1 0.4 0.0 0.5 0.0 1.3 23.1 28.5 0.0 1.6 0.9 8.7 0.8 14.2 0.0 0.0 54.6 0.0 3.0 0.3 13.1 11.7 15.1 0.0 18.7 1.7 1.2 36.0 1.3 0.0 2.3 1.7 0.3 3.8 25.3 18.0 8.2 1.3 6.4 12.3 21.1 IL21 "IL-21, Za11" ENSG00000138684 "Interleukin 21" Q9HBE4 4 122610108-122621066 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "lymphoid tissue: 5.9" "Group enriched" "Detected in some" 18 "Early spermatids: 13.7;Late spermatids: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 55700 "Cluster 16: Immune cells - Immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (2.42e-1)" "unprognostic (2.12e-1)" "unprognostic (6.80e-2)" 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.0 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 IL22 "IL-21, IL-22, IL-D110, IL-TIF, ILTIF, MGC79382, MGC79384, TIFa, TIFIL-23, zcyto18" ENSG00000127318 "Interleukin 22" Q9GZX6 12 68248242-68253604 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 1.1;Langerhans cells: 3.4;T-cells: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 86900 "Cluster 14: B-cells - Humoral immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.57e-1)" "unprognostic (4.24e-2)" 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 2.1 0.0 0.0 0.0 IL22RA2 "CRF2-S1, IL-22BP" ENSG00000164485 "Interleukin 22 receptor subunit alpha 2" Q969J5 6 137143820-137173648 "Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "breast: 3.6;lymphoid tissue: 3.2" "Group enriched" "Detected in some" 5 "Breast glandular cells: 8.9;Breast myoepithelial cells: 9.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-937: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030582, CAB034906" Uncertain "Secreted to blood" NA NA 40500000 "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 35: Glandular cells - Unknown function" "CAB034906: AB_2124501, HPA030582: AB_10600716" "unprognostic (1.09e-1)" "unprognostic (7.97e-4)" "unprognostic (1.32e-3)" "unprognostic (1.24e-2)" "unprognostic (4.03e-3)" "unprognostic (1.11e-1)" "unprognostic (4.51e-1)" "unprognostic (1.92e-1)" "unprognostic (1.07e-1)" "unprognostic (1.10e-1)" "unprognostic (7.58e-2)" "unprognostic (1.32e-1)" "unprognostic (1.62e-1)" "unprognostic (6.61e-2)" 0.0 0.0 0.0 1.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.0 1.1 0.3 0.0 0.0 0.3 0.0 0.0 3.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.3 0.1 0.0 0.0 0.0 8.9 9.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.1 IL23A "IL-23, IL-23A, IL23P19, P19, SGRF" ENSG00000110944 "Interleukin 23 subunit alpha" Q9NPF7 12 56334174-56340410 "FDA approved drug targets, Predicted secreted proteins" "Antiviral defense, Immunity, Inflammatory response, Innate immunity, Tissue remodeling" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "urinary bladder: 44.5" "Cell type enhanced" "Detected in many" "Ductal cells: 43.4;Ionocytes: 73.2;Langerhans cells: 151.8;Pancreatic endocrine cells: 70.5;Spermatocytes: 41.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "MAIT T-cell: 14.1;memory B-cell: 18.9;memory CD4 T-cell: 25.7;memory CD8 T-cell: 12.5;naive B-cell: 21.5;naive CD4 T-cell: 28.1;naive CD8 T-cell: 17.6;T-reg: 15.6" "Group enriched" "Detected in many" 12 "B-cells: 21.5;T-cells: 28.1" "Cell line enhanced" "Detected in some" "A-431: 15.3;CAPAN-2: 25.6;U-266/70: 42.1;U-266/84: 20.5" "Region enhanced" "Detected in some" "white matter: 3.9" "Not detected" "Not detected" HPA001554 Approved Approved Cytosol "Secreted to blood" NA NA 11000 "Cluster 30: Non-specific - Translation" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA001554: AB_1079135" "unprognostic (2.34e-1)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" "unprognostic (1.06e-1)" "unprognostic (5.24e-2)" "unprognostic (4.01e-3)" "unprognostic (4.40e-1)" "unprognostic (1.43e-3)" "unprognostic (1.30e-1)" "unprognostic (6.79e-2)" "unprognostic (3.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.03e-10)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.83e-1)" "unprognostic (4.50e-3)" 0.6 0.3 0.3 2.1 0.2 3.2 0.3 0.1 0.2 0.4 0.1 0.4 0.2 1.0 0.5 4.5 0.4 0.9 0.3 0.4 0.2 0.6 1.1 1.2 4.2 0.3 0.2 0.3 0.7 0.0 0.6 0.6 0.2 0.5 0.3 0.1 1.3 0.2 0.2 0.7 1.9 0.0 0.2 2.2 0.7 4.4 0.3 7.2 0.4 0.0 8.8 44.5 0.5 0.3 15.3 0.3 0.5 0.5 0.0 0.0 1.3 0.3 0.1 0.0 0.0 0.5 25.6 0.9 7.5 0.0 0.8 1.3 0.0 2.5 0.1 1.1 0.5 0.4 0.3 1.2 0.0 0.3 0.9 0.1 0.0 0.0 0.7 3.1 0.0 3.5 0.6 6.2 0.1 0.6 0.6 0.8 2.2 0.3 0.4 0.4 0.2 0.6 8.9 7.4 0.5 0.6 0.3 0.4 1.4 2.1 0.2 7.0 0.5 0.5 0.5 0.4 1.8 42.1 20.5 2.1 0.5 3.7 0.4 0.0 0.4 0.0 2.8 0.0 14.1 18.9 25.7 12.5 0.9 21.5 28.1 17.6 0.2 2.0 0.1 0.1 15.6 10.0 0.3 0.2 0.1 0.2 0.4 0.2 0.3 0.2 0.2 0.2 0.3 0.3 0.5 3.2 2.2 0.0 13.6 3.6 12.1 16.2 0.6 0.0 1.2 1.4 0.4 0.0 23.7 1.8 0.0 0.4 1.5 1.1 1.9 43.4 6.9 11.1 1.0 1.4 0.0 0.0 0.3 7.4 0.5 2.3 1.5 16.6 0.0 0.3 0.0 0.5 2.5 0.0 0.2 1.0 73.2 0.8 151.8 4.2 0.3 14.7 8.8 0.0 34.7 0.5 0.0 0.0 0.3 70.5 0.1 0.7 7.4 6.1 0.4 0.6 15.3 0.5 0.0 0.4 1.4 41.9 6.9 0.6 4.0 0.0 14.4 0.2 2.0 16.3 IL24 "C49A, FISP, IL-24, IL10B, mda-7, Mob-5, ST16" ENSG00000162892 "Interleukin 24" Q13007 1 206897443-206904139 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 15.2;lymphoid tissue: 25.5;urinary bladder: 14.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.8;Basal prostatic cells: 2.9;Fibroblasts: 11.6;Smooth muscle cells: 7.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 9.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 10 "B-cells: 5.4;T-cells: 3.6" "Cell line enriched" "Detected in some" 9 "BJ hTERT+: 172.7" "Not detected" "Not detected" "Not detected" "Not detected" CAB025972 Uncertain "Secreted to blood" NA NA 140000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB025972: " "prognostic favorable (5.09e-4)" "unprognostic (3.79e-1)" "unprognostic (2.89e-2)" "unprognostic (4.09e-3)" "unprognostic (3.98e-1)" "unprognostic (2.68e-1)" "unprognostic (2.85e-2)" "unprognostic (2.20e-2)" "unprognostic (3.98e-1)" "unprognostic (3.35e-2)" "unprognostic (8.04e-2)" "unprognostic (7.63e-2)" "unprognostic (3.43e-4)" "unprognostic (5.41e-2)" "unprognostic (1.29e-1)" "unprognostic (7.91e-2)" "unprognostic (3.33e-2)" 3.5 0.1 0.1 3.6 0.1 1.5 0.7 0.1 0.2 0.4 0.2 1.3 0.0 1.0 0.0 0.9 1.0 1.3 0.8 0.1 0.3 0.8 1.2 1.8 5.8 0.2 0.4 0.2 0.2 0.0 0.5 0.9 0.3 1.0 0.0 0.0 1.1 0.0 3.8 0.2 15.2 0.1 0.1 25.5 0.6 0.1 0.3 0.0 1.0 0.0 0.2 14.6 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 172.7 0.0 0.4 0.0 0.5 0.2 0.1 0.0 3.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.2 2.5 18.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 16.7 0.7 0.0 0.0 0.0 2.3 1.2 7.4 0.5 2.5 0.8 0.3 1.4 0.0 0.2 0.0 0.0 0.0 0.8 0.0 1.9 5.4 1.7 2.7 0.0 5.0 3.6 2.9 0.4 0.4 0.0 0.0 1.9 0.8 0.1 0.1 0.1 0.2 0.1 0.3 0.2 0.4 0.3 0.1 0.3 0.1 0.2 0.0 1.3 0.0 1.8 6.8 2.9 0.5 0.0 0.0 0.4 0.3 1.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.1 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.2 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 7.9 0.0 0.0 0.0 1.3 0.0 0.6 0.0 0.1 0.7 IL25 "IL-17E, IL-25, IL17E" ENSG00000166090 "Interleukin 25" Q9H293 14 23372809-23376403 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 22 "Cardiomyocytes: 19.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB024864 Uncertain "Secreted to blood" NA NA 4230000 "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB024864: " "unprognostic (1.49e-1)" "unprognostic (6.82e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 IL26 "AK155, IL-26" ENSG00000111536 "Interleukin 26" Q9NPH9 12 68201349-68225810 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.6;T-cells: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HDLM-2: 13.5" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 35700 "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (2.71e-1)" "unprognostic (8.87e-2)" "unprognostic (3.26e-5)" "unprognostic (7.10e-2)" "unprognostic (5.90e-2)" "unprognostic (2.96e-1)" "unprognostic (3.69e-5)" "unprognostic (3.80e-1)" "unprognostic (5.08e-2)" "unprognostic (1.12e-3)" "unprognostic (1.79e-2)" 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 3.8 0.1 0.0 0.0 IL27 "IL-27, IL-27A, IL27A, IL27p28, IL30, MGC71873, p28" ENSG00000197272 "Interleukin 27" Q8NEV9 16 28499362-28512051 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Antiviral protein, Cytokine" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 26.7" "Group enriched" "Detected in some" 5 "Hepatocytes: 18.1;Syncytiotrophoblasts: 23.1" "Cancer enriched" "Detected in some" 8 "liver cancer: 4.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.6;intermediate monocyte: 3.8" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 11 "BEWO: 17.9" "Not detected" "Not detected" "Not detected" "Not detected" CAB024722 Approved "Secreted to blood" NA NA 521000 "Cluster 7: Monocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB024722: " "unprognostic (4.79e-3)" "unprognostic (2.66e-3)" "unprognostic (4.72e-2)" "unprognostic (1.52e-1)" "unprognostic (2.09e-1)" "unprognostic (6.55e-3)" "prognostic favorable (1.30e-4)" "unprognostic (3.76e-2)" "unprognostic (8.23e-3)" "unprognostic (1.29e-2)" "unprognostic (6.07e-3)" "unprognostic (4.57e-2)" "unprognostic (2.41e-7)" "unprognostic (6.44e-2)" "unprognostic (1.04e-3)" "unprognostic (2.13e-1)" "unprognostic (2.83e-2)" 0.2 0.2 0.2 1.2 0.1 0.9 0.1 0.3 0.4 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.2 0.1 26.7 0.5 0.4 0.4 0.4 0.0 0.1 0.0 0.1 0.7 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 1.7 0.1 0.6 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 17.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.4 3.6 0.8 0.0 3.8 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.0 2.1 1.5 0.1 0.0 0.2 1.0 0.2 0.1 0.3 0.4 0.3 0.2 0.4 0.4 0.2 0.3 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 3.1 0.0 0.0 0.1 0.0 0.0 0.0 18.1 0.9 0.0 0.4 0.0 0.0 3.5 1.2 0.1 0.0 2.3 0.0 0.0 2.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.1 0.0 0.0 0.0 IL2RB "CD122, IL15RB" ENSG00000100385 "Interleukin 2 receptor subunit beta" P14784 22 37125843-37175054 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 50.2;placenta: 36.3" "Cell type enhanced" "Detected in many" "dendritic cells: 130.1;Extravillous trophoblasts: 85.5;NK-cells: 388.3;T-cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 50.8;NK-cell: 186.4" "Group enriched" "Detected in many" 22 "NK-cells: 186.4;T-cells: 50.8" "Cell line enriched" "Detected in some" 8 "HDLM-2: 525.8" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Low region specificity" "Detected in some" HPA062657 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA062657: AB_2684822" "unprognostic (3.38e-3)" "unprognostic (1.21e-2)" "prognostic favorable (6.76e-4)" "prognostic favorable (3.18e-5)" "unprognostic (2.44e-2)" "unprognostic (9.69e-3)" "unprognostic (2.60e-1)" "unprognostic (5.22e-2)" "unprognostic (1.03e-3)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.50e-7)" "unprognostic (4.63e-2)" "unprognostic (7.96e-2)" "unprognostic (3.94e-3)" "unprognostic (2.46e-2)" 3.2 1.3 2.0 22.4 1.6 36.8 1.9 0.8 2.3 2.2 1.5 5.1 5.5 7.6 2.9 3.5 2.9 6.8 1.9 2.2 1.0 1.0 8.5 12.4 35.7 2.4 2.2 1.6 0.8 0.4 0.6 36.3 1.9 2.3 5.2 0.0 4.3 3.2 0.7 8.9 8.3 2.5 1.7 50.2 6.4 1.5 3.3 14.9 1.8 0.7 24.0 8.0 1.0 1.8 0.4 0.0 1.0 0.0 0.0 0.0 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 525.8 0.6 1.0 0.0 0.1 0.0 0.0 24.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.3 0.0 0.7 0.1 4.2 3.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.2 0.6 2.3 0.0 0.9 0.0 0.0 13.2 0.0 0.6 36.2 66.0 0.1 0.4 0.4 0.5 5.4 0.1 0.5 50.8 0.6 27.4 0.4 11.4 28.6 0.1 1.9 3.6 15.0 1.2 186.4 0.5 0.3 24.4 37.3 2.0 1.6 0.8 2.3 2.2 1.0 2.4 2.2 1.9 1.7 3.3 1.8 1.5 3.2 6.8 0.0 3.6 3.2 0.7 0.1 5.7 0.0 1.0 0.8 1.7 0.0 0.6 1.8 0.0 0.6 130.1 0.2 0.0 0.3 2.2 0.5 1.2 1.0 0.0 16.8 0.1 0.2 85.5 1.4 5.6 1.2 10.1 0.1 7.1 1.8 2.3 0.0 0.1 0.1 0.0 5.3 1.7 1.6 0.3 3.7 5.4 0.0 2.0 0.0 388.3 0.0 0.1 0.0 0.0 0.0 18.6 0.2 0.1 0.2 0.7 0.0 0.0 0.2 0.9 0.0 0.3 0.5 1.6 1.2 103.6 0.0 0.3 0.1 IL3 "IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF" ENSG00000164399 "Interleukin 3" P08700 5 132060655-132063204 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "HMC-1: 2.8" "Not detected" "Not detected" "Secreted to blood" NA NA 17800 "Cluster 3: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (9.74e-2)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IL31 IL-31 ENSG00000204671 "Interleukin 31" Q6EBC2 12 122172029-122174221 "Predicted secreted proteins" Immunity Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Early spermatids: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025657 Uncertain "Secreted to blood" NA NA 37800 "Cluster 34: Spermatids - Unknown function" "CAB025657: " "unprognostic (1.70e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL31RA "CRL, CRL3, GLM-R, Glmr, IL-31RA" ENSG00000164509 "Interleukin 31 receptor A" Q8NI17 5 55851357-55922854 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.6;lymphoid tissue: 2.1;testis: 1.8" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Late spermatids: 1.2;Spermatocytes: 2.5;Syncytiotrophoblasts: 1.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 26.3;HBEC3-KT: 10.3;HHSteC: 9.5;hTERT-HME1: 11.5;U-2 OS: 16.8;U-87 MG: 20.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "HPA051532, HPA068114" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA051532: , HPA068114: AB_2732779" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.13e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-3)" "unprognostic (7.34e-2)" "unprognostic (3.54e-1)" "unprognostic (5.38e-2)" "unprognostic (2.95e-3)" "unprognostic (7.75e-5)" "unprognostic (5.55e-2)" "unprognostic (2.65e-6)" "unprognostic (7.73e-2)" "unprognostic (7.68e-2)" "unprognostic (4.02e-1)" "unprognostic (1.76e-2)" 0.0 0.0 0.1 0.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.1 1.8 0.0 2.1 0.0 0.6 0.1 0.1 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.4 0.5 0.2 0.5 0.3 0.1 0.0 0.2 0.0 0.0 0.4 26.3 0.0 0.0 10.3 2.2 0.0 0.1 0.0 0.0 0.0 9.5 0.0 0.0 7.3 2.9 4.8 11.5 0.6 4.1 0.1 0.0 0.4 1.4 0.0 0.0 1.2 0.0 0.0 6.8 0.0 1.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.5 2.0 0.5 16.8 0.0 0.8 0.0 0.0 0.0 20.8 0.0 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.3 0.3 0.0 0.0 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.1 2.5 0.6 0.0 0.1 1.1 0.0 0.7 0.0 0.0 IL32 "NK4, TAIF, TAIFb, TAIFd" ENSG00000008517 "Interleukin 32" P24001 16 3065297-3082192 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 829.3;pancreas: 674.4" "Cell type enhanced" "Detected in many" "Ductal cells: 1696.0;Exocrine glandular cells: 1490.0;Pancreatic endocrine cells: 2546.1;Proximal enterocytes: 4916.6;Proximal tubular cells: 4315.8;T-cells: 1711.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 4625.7" "Lineage enriched" "Detected in all" 8 "T-cells: 4625.7" "Cell line enhanced" "Detected in many" "CACO-2: 514.7;CAPAN-2: 328.6;HDLM-2: 707.9;Hep G2: 504.3;Karpas-707: 404.6;MOLT-4: 319.9;RH-30: 348.0;U-937: 314.5" "HPA029397, CAB030029" Uncertain "Secreted to blood" NA NA 46100 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB030029: AB_1089175, HPA029397: AB_10612120" "unprognostic (2.00e-2)" "unprognostic (2.89e-2)" "unprognostic (2.86e-1)" "prognostic favorable (1.33e-4)" "unprognostic (2.95e-2)" "unprognostic (1.32e-1)" "unprognostic (8.02e-2)" "unprognostic (2.58e-2)" "unprognostic (1.73e-3)" "unprognostic (2.19e-2)" "unprognostic (3.32e-3)" "unprognostic (3.51e-1)" "unprognostic (3.30e-2)" "unprognostic (8.08e-2)" "unprognostic (3.86e-2)" "unprognostic (3.16e-2)" "unprognostic (4.29e-3)" 91.1 36.7 21.3 206.7 21.0 49.1 58.7 20.3 27.6 19.2 19.0 206.5 339.8 30.4 13.5 45.5 20.6 117.4 180.6 19.1 20.0 418.8 829.3 271.5 402.7 24.0 20.4 22.3 674.4 10.2 17.7 62.8 23.0 54.2 142.7 1.0 87.1 42.2 543.7 26.9 558.9 88.4 21.2 440.7 87.4 19.2 24.8 198.0 84.3 328.6 200.2 118.8 23.1 21.3 254.1 10.7 1.2 0.3 0.5 28.4 19.5 12.4 31.3 14.9 24.8 514.7 328.6 0.6 59.8 7.0 92.1 10.7 1.0 29.6 18.0 707.9 2.7 1.2 49.8 504.3 55.7 1.4 20.5 34.2 3.4 12.9 54.9 12.1 60.0 7.9 0.7 404.6 19.5 1.7 319.9 8.2 7.2 3.2 7.6 0.7 348.0 34.4 239.3 16.7 0.7 3.9 109.9 7.4 1.9 50.9 7.2 4.0 161.6 56.9 67.2 3.1 36.5 4.7 10.7 1.6 1.1 314.5 29.7 30.8 10.9 12.7 2570.7 9.1 2584.2 9.3 2337.1 2483.4 9.2 7.8 884.8 1712.5 46.9 553.7 11.3 13.4 4625.7 2238.1 21.3 21.0 20.3 27.6 19.1 20.0 24.0 20.4 23.0 21.2 24.8 21.3 334.4 198.7 64.9 0.0 81.7 59.5 68.0 462.2 12.0 0.4 50.3 44.3 5.6 221.6 119.6 119.5 0.0 9.0 550.3 1038.3 252.4 1696.0 0.2 46.5 36.7 286.4 135.1 64.6 0.1 1490.0 14.1 136.7 118.3 53.7 52.6 1.5 68.6 124.1 4.2 0.0 0.1 273.1 244.1 40.5 116.1 1.9 35.1 60.7 65.8 5.6 225.8 0.0 518.0 0.0 0.1 2546.1 1004.5 45.9 81.7 101.2 4916.6 4315.8 55.1 0.6 19.7 278.5 117.4 5.8 1.3 7.1 51.6 6.6 1711.8 27.8 182.2 105.7 IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.0;dendritic cells: 137.5;Endothelial cells: 83.2;Langerhans cells: 47.6;monocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2665.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2665.0" "Cell line enhanced" "Detected in many" "HDLM-2: 128.8;NB-4: 24.9;RPMI-8226: 54.1" "HPA003539, CAB018374" Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" 25.2 2.9 7.1 15.8 13.6 25.0 20.6 16.1 11.7 6.4 0.2 8.1 5.5 8.7 1.6 5.4 8.0 11.3 13.0 5.9 8.1 9.2 1.8 25.0 25.1 11.7 10.6 8.8 5.4 3.4 2.8 6.2 11.1 7.0 6.6 22.0 9.5 3.2 12.1 12.7 9.2 12.3 7.5 11.1 6.9 3.5 10.1 4.4 10.3 8.6 13.0 12.4 6.3 20.5 0.2 9.4 3.6 1.3 0.1 0.0 1.1 1.2 0.3 0.0 0.1 0.9 1.5 1.2 7.2 0.2 0.6 9.6 0.0 0.0 0.0 128.8 3.9 0.6 2.1 0.4 0.0 0.8 15.6 0.0 0.0 0.0 0.0 4.1 8.2 0.9 0.3 6.1 0.0 1.4 0.7 24.9 3.1 0.8 0.5 1.4 4.2 54.1 0.0 1.4 0.6 0.4 0.6 0.3 2.8 1.8 1.2 17.8 0.4 0.5 1.5 0.5 0.3 12.5 3.9 1.1 9.8 2.8 0.1 2665.0 5.6 83.9 0.6 31.7 1.0 2.5 0.9 0.5 14.9 8.9 0.7 0.7 4.6 14.2 42.5 628.5 0.5 12.0 7.1 13.6 16.1 11.7 5.9 8.1 11.7 10.6 11.1 7.5 10.1 20.5 79.0 3.2 1.8 11.8 6.8 5.9 0.7 0.9 1.2 2.3 0.5 0.9 2.2 1.5 1.0 0.0 10.4 0.1 137.5 4.7 0.0 0.4 0.2 2.7 1.4 83.2 0.0 3.0 7.3 0.2 0.1 4.3 0.5 1.5 11.4 0.4 24.3 0.7 4.6 0.0 14.3 7.3 0.0 2.8 47.6 0.1 0.3 32.9 8.8 13.1 72.6 0.6 1.0 6.0 18.2 0.1 3.4 0.7 4.0 0.7 0.2 0.0 0.4 3.2 0.0 3.6 3.2 0.1 0.7 0.7 5.5 0.3 1.6 1.3 0.6 2.1 IL4 "BCGF-1, BCGF1, BSF1, IL-4, MGC79402" ENSG00000113520 "Interleukin 4" P05112 5 132673986-132682678 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "B-cell activation" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "T-cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 861 "basophil: 474.9" "Lineage enriched" "Detected in single" 861 "granulocytes: 474.9" "Cell line enriched" "Detected in some" 5 "MOLT-4: 21.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA072995, CAB078477" Approved "Secreted to blood" NA NA 13600 "Cluster 38: Basophils - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB078477: AB_417057, HPA072995: AB_2732215" "unprognostic (3.40e-2)" "unprognostic (9.19e-2)" "unprognostic (1.41e-1)" "unprognostic (2.49e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-1)" "unprognostic (1.69e-1)" "unprognostic (7.33e-2)" "unprognostic (2.26e-2)" "unprognostic (1.96e-1)" "unprognostic (1.47e-10)" "unprognostic (9.21e-3)" "unprognostic (2.88e-1)" "unprognostic (4.93e-2)" "unprognostic (1.24e-2)" 0.1 0.3 0.1 0.4 0.1 0.3 0.1 0.5 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.2 0.3 0.0 0.1 0.2 0.0 0.0 0.3 0.3 0.3 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.0 0.5 0.3 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 474.9 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.5 0.3 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 IL4I1 FIG1 ENSG00000104951 "Interleukin 4 induced 1" Q96RQ9 19 49889654-49929539 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 18.3;testis: 26.8" "Group enriched" "Detected in many" 5 "Langerhans cells: 295.1;monocytes: 682.5" "Cancer enhanced" "Detected in all" "ovarian cancer: 35.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 103.4" "Group enriched" "Detected in many" 6 "monocytes: 36.8;T-cells: 103.4" "Cell line enhanced" "Detected in many" "EFO-21: 34.3;HDLM-2: 62.4;Karpas-707: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045598 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cytosol" "HPA045598: AB_10969138" "unprognostic (6.23e-2)" "unprognostic (1.32e-2)" "unprognostic (8.39e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.61e-2)" "unprognostic (3.74e-3)" "unprognostic (7.03e-2)" "unprognostic (2.52e-2)" "unprognostic (3.84e-3)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.23e-10)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" "unprognostic (6.44e-2)" "unprognostic (2.11e-3)" 1.6 0.6 0.4 18.3 0.6 4.2 0.9 0.8 0.6 1.1 0.7 1.7 4.1 1.6 0.2 0.6 3.9 2.0 0.5 0.6 0.5 4.8 1.2 2.4 9.3 1.7 0.9 0.4 0.7 0.2 0.6 1.9 1.8 0.8 1.4 0.1 0.9 0.5 0.3 1.3 2.7 1.5 1.0 4.1 3.1 26.8 1.2 3.4 0.5 0.2 6.7 4.5 0.5 2.3 1.0 1.2 0.8 0.7 0.0 0.8 0.3 0.5 2.0 1.4 2.1 0.7 1.9 3.5 34.3 0.4 2.9 0.5 0.4 0.0 0.2 62.4 0.2 1.6 0.1 0.5 0.1 1.2 12.3 1.0 0.4 0.6 0.1 0.4 2.6 0.4 0.4 47.3 0.1 0.4 0.7 2.1 0.4 0.9 0.1 1.0 0.9 3.6 2.5 3.2 0.7 0.8 0.5 0.9 0.5 0.2 0.4 2.8 2.9 7.1 1.0 0.1 1.0 4.1 9.7 2.0 1.0 0.5 0.7 0.3 22.0 0.3 6.4 36.8 103.4 0.4 13.2 11.5 11.6 0.2 0.3 0.1 0.5 1.3 5.3 1.3 0.7 8.8 0.4 0.6 0.8 0.6 0.6 0.5 1.7 0.9 1.8 1.0 1.2 2.3 0.8 0.0 0.0 0.0 3.6 9.7 0.6 9.8 0.0 0.1 1.2 1.3 0.5 0.0 5.5 3.7 0.0 0.4 1.0 0.2 0.0 3.5 75.4 2.9 0.6 6.7 0.0 0.0 0.4 4.0 0.7 1.3 0.5 2.1 1.3 0.1 1.1 0.2 97.4 0.0 0.4 0.3 6.1 3.0 295.1 18.4 0.3 38.8 3.6 1.9 682.5 0.1 1.0 0.0 0.4 0.5 0.1 0.4 0.7 1.4 0.3 2.7 1.6 0.2 0.0 0.2 2.5 45.2 3.6 0.4 8.2 0.8 6.3 0.0 0.2 2.1 IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 92.0;granulocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 78.1" "Group enriched" "Detected in all" 5 "B-cells: 78.1;granulocytes: 31.1" "Cell line enhanced" "Detected in many" "Daudi: 124.2;HBEC3-KT: 115.0;HDLM-2: 110.6;U-698: 119.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 38500 110000 "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" 49.4 45.2 22.7 82.3 19.7 103.4 34.1 19.2 22.0 39.7 21.4 97.0 27.3 35.8 5.9 70.8 42.3 41.2 34.2 18.7 21.0 50.8 116.0 119.2 117.1 29.4 22.2 14.3 29.8 31.7 14.9 39.3 24.0 49.9 35.6 2.4 20.5 25.6 9.3 24.4 55.7 37.3 25.5 90.0 55.0 15.5 25.3 22.3 24.2 6.6 89.6 63.2 45.4 23.8 39.9 10.1 6.4 13.1 3.1 14.1 14.3 24.7 27.3 9.3 7.7 20.4 105.2 124.2 30.1 38.5 18.3 39.7 7.3 115.0 8.2 110.6 4.0 22.6 6.6 31.6 40.8 6.1 61.7 23.5 45.0 44.2 26.5 48.7 50.7 6.8 10.5 9.8 15.0 17.3 0.7 18.8 8.0 34.2 9.1 0.4 47.5 10.2 42.9 43.2 1.9 0.6 3.7 24.7 5.0 15.6 8.2 23.5 81.0 21.0 9.8 19.0 17.6 6.1 2.1 119.7 2.1 21.1 0.3 1.4 7.2 13.0 4.2 3.1 3.4 25.8 6.9 4.4 4.1 78.1 10.0 5.0 31.1 8.2 1.8 4.8 5.3 5.8 22.7 19.7 19.2 22.0 18.7 21.0 29.4 22.2 24.0 25.5 25.3 23.8 30.5 28.9 49.2 0.7 92.0 13.3 43.3 34.9 26.2 0.3 9.4 14.2 2.4 34.3 33.4 1.8 0.0 17.6 29.8 60.0 0.0 39.5 0.3 6.6 2.2 39.0 23.4 5.2 1.7 32.3 3.8 17.2 32.1 17.2 110.8 0.7 62.8 45.9 27.2 0.0 0.6 35.5 8.2 30.6 29.9 0.8 0.3 34.3 14.2 38.4 39.3 0.0 7.2 0.5 0.7 49.3 28.7 0.0 13.4 37.7 24.0 1.2 28.5 0.2 39.5 16.4 20.0 0.8 3.3 23.8 14.9 24.9 38.3 0.2 16.7 46.9 IL5 "EDF, IL-5, TRF" ENSG00000113525 "Interleukin 5" P05113 5 132541445-132556838 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;testis: 5.1" "Cell type enriched" "Detected in some" 7 "Spermatocytes: 19.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "memory B-cell: 1.4" "Lineage enriched" "Detected in single" 8 "B-cells: 1.4" "Cell line enhanced" "Detected in some" "Hep G2: 2.8;TIME: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" CAB010304 Approved "Secreted to blood" NA NA 4130 "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB010304: AB_2296159" "unprognostic (1.66e-1)" "unprognostic (4.76e-2)" "unprognostic (5.30e-3)" "unprognostic (2.35e-1)" "unprognostic (9.07e-2)" "unprognostic (7.98e-2)" "unprognostic (2.03e-2)" "unprognostic (3.51e-2)" "unprognostic (1.97e-1)" "unprognostic (1.44e-2)" "unprognostic (1.53e-1)" "unprognostic (2.09e-1)" "unprognostic (5.27e-2)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" 0.1 0.0 0.8 0.1 0.3 0.0 0.0 1.7 1.2 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.3 0.5 0.2 1.5 0.3 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.0 0.2 5.1 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.1 0.3 0.1 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.3 1.7 1.2 1.5 0.3 0.3 0.1 0.8 0.8 0.5 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 1.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.7 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.1 0.0 19.5 1.2 0.0 0.1 0.0 1.6 0.0 0.0 0.0 IL6 "BSF2, HGF, HSF, IFNB2, IL-6" ENSG00000136244 "Interleukin 6" P05231 7 22725884-22732002 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 217.6;urinary bladder: 281.3" "Group enriched" "Detected in many" 4 "Adipocytes: 188.5;Endometrial ciliated cells: 163.9;Endothelial cells: 287.4;Fibroblasts: 593.3;Glandular and luminal cells: 322.2;Smooth muscle cells: 449.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 44 "memory B-cell: 3.9;naive B-cell: 4.8" "Lineage enriched" "Detected in single" 48 "B-cells: 4.8" "Group enriched" "Detected in many" 4 "BJ hTERT+: 2214.7;GAMG: 1447.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB023406, CAB072821" Supported Approved Vesicles "Secreted to blood" NA NA 5700 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB023406: AB_617317, CAB072821: " "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (3.59e-2)" "unprognostic (9.88e-3)" "unprognostic (1.35e-1)" "unprognostic (3.07e-3)" "unprognostic (3.25e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (1.10e-11)" "unprognostic (2.45e-3)" "unprognostic (2.10e-1)" "unprognostic (4.31e-2)" "unprognostic (7.80e-2)" 217.6 13.9 3.6 30.8 3.8 46.8 31.3 3.7 6.0 4.7 9.2 22.1 1.9 5.7 0.0 34.9 18.9 41.6 55.1 3.8 3.8 17.7 13.0 114.9 9.1 4.0 4.3 6.2 19.5 10.0 38.3 11.3 4.9 16.5 17.3 1.4 12.0 2.0 7.8 7.6 8.3 19.5 3.9 7.0 18.0 1.2 4.7 6.3 14.2 4.1 3.7 281.3 5.7 4.1 0.1 0.0 0.0 0.0 0.7 2.2 7.5 8.9 2214.7 43.2 151.0 0.0 0.6 0.2 71.6 15.2 1447.6 1.7 0.0 0.3 59.9 94.2 0.2 0.0 3.7 0.0 47.3 0.0 0.6 5.6 0.0 413.8 63.1 44.2 18.2 0.0 10.6 0.5 1.9 0.1 0.0 0.3 1.6 0.7 0.5 0.0 0.0 0.0 124.2 0.0 0.0 0.0 144.5 0.1 0.6 7.9 0.1 0.1 14.5 15.2 1.4 28.2 4.7 0.0 27.8 0.4 98.5 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.6 3.8 3.7 6.0 3.8 3.8 4.0 4.3 4.9 3.9 4.7 4.1 188.5 6.4 22.7 0.0 27.0 44.6 3.4 28.5 1.8 0.1 1.4 1.1 1.4 0.0 17.7 3.7 0.0 1.1 0.4 0.1 0.0 9.8 0.4 163.9 44.6 287.4 0.0 0.0 0.0 2.8 4.0 593.3 0.0 322.2 6.3 0.0 3.6 0.1 4.1 0.0 0.0 0.0 0.0 9.3 76.5 0.2 0.0 27.4 40.9 2.8 4.2 0.0 0.0 0.0 0.1 4.3 0.1 0.0 0.9 16.4 0.0 0.0 8.1 0.0 0.0 28.9 449.0 0.0 0.1 0.4 33.4 1.4 8.6 0.2 0.0 20.6 IL6R CD126 ENSG00000160712 "Interleukin 6 receptor" P08887 1 154405193-154469450 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.3;skeletal muscle: 94.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 115.4;Hepatocytes: 108.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 88.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 224.4;U-266/84: 274.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 24800000 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 16: U-266 - Nucleosome" "Cluster 41: Macrophages - Immune response" "unprognostic (1.19e-1)" "unprognostic (3.97e-1)" "unprognostic (1.19e-1)" "unprognostic (1.08e-1)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-2)" "unprognostic (3.27e-1)" "unprognostic (6.42e-2)" "prognostic favorable (1.65e-4)" "unprognostic (7.94e-2)" "unprognostic (1.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.51e-1)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" 11.0 5.8 6.8 25.5 8.0 16.6 5.9 7.4 11.3 7.6 4.8 14.7 15.6 8.4 2.5 7.4 12.4 9.0 6.6 6.2 6.4 14.2 58.3 16.3 27.3 10.9 8.8 8.9 8.7 1.2 8.9 6.6 9.8 6.0 9.8 1.4 3.3 2.9 94.2 6.4 19.8 8.8 10.4 19.8 10.2 3.4 10.6 9.3 2.7 26.4 22.4 9.3 5.3 10.4 3.3 5.8 0.4 0.4 3.4 5.1 0.4 3.3 2.5 2.0 1.0 0.6 3.9 0.2 7.4 4.1 12.0 1.7 1.1 17.8 1.6 62.6 1.9 0.8 2.2 13.9 0.5 9.6 5.0 3.0 10.5 1.7 26.1 0.6 2.6 0.1 0.7 24.0 0.6 1.4 0.2 16.0 1.8 1.1 13.5 0.3 0.3 53.6 10.9 4.5 0.5 0.3 1.1 36.2 59.5 4.5 3.3 224.4 2.5 3.5 3.4 3.3 2.2 43.1 274.1 0.4 4.4 61.0 5.7 7.5 29.4 28.1 0.6 18.0 1.5 1.5 15.2 1.6 36.1 0.6 14.9 5.4 88.2 1.3 8.0 13.1 21.2 15.8 6.8 8.0 7.4 11.3 6.2 6.4 10.9 8.8 9.8 10.4 10.6 10.4 3.4 115.4 82.7 18.6 11.0 37.9 72.9 8.3 13.1 0.1 7.5 7.4 9.9 25.8 33.9 1.8 0.0 0.5 16.9 38.5 0.0 4.3 35.1 34.1 5.7 10.9 7.7 3.8 5.7 1.2 1.2 26.3 25.5 48.7 61.3 1.3 3.9 108.6 42.9 0.0 5.9 6.5 14.2 41.8 79.3 14.5 0.3 63.7 24.9 44.0 76.8 3.8 4.1 3.0 3.3 7.5 8.7 0.4 41.9 58.9 60.1 15.5 29.0 0.2 0.0 28.3 19.2 0.4 1.1 7.2 29.7 1.0 17.1 0.1 15.4 17.0 IL6ST "CD130, GP130, sGP130" ENSG00000134352 "Interleukin 6 signal transducer" P40189 5 55935095-55995022 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 580.3;Hepatic stellate cells: 808.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 16.7" "Lineage enriched" "Detected in many" 4 "T-cells: 16.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 151.3;BJ hTERT+: 175.2;HHSteC: 155.1;HSkMC: 135.1;TIME: 147.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010558, CAB025784" Approved Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 160000000 "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Golgi apparatus" "CAB025784: , HPA010558: AB_1078439" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (3.95e-2)" "unprognostic (8.93e-2)" "unprognostic (3.99e-2)" "unprognostic (5.18e-2)" "unprognostic (9.53e-3)" "unprognostic (1.89e-2)" "unprognostic (2.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (3.69e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" 67.1 46.0 26.8 14.1 31.0 9.6 51.3 30.9 36.7 43.0 21.3 33.9 4.2 35.2 18.5 18.4 34.2 23.6 35.1 23.5 31.4 30.0 77.6 53.3 15.9 32.1 27.0 36.9 21.9 39.6 22.5 101.7 35.9 32.6 14.3 28.6 31.9 29.9 41.0 17.8 31.1 28.7 35.1 34.7 27.8 8.9 25.3 23.6 40.4 34.7 16.2 37.7 35.1 42.9 14.4 35.6 9.4 18.8 75.5 151.3 22.3 54.5 175.2 44.1 62.4 40.5 16.3 1.1 33.7 52.5 71.6 7.8 9.8 19.2 84.1 1.6 8.5 4.6 20.1 14.2 155.1 0.4 6.2 135.1 11.1 103.1 42.7 43.6 101.8 1.9 3.7 51.0 47.0 2.9 0.7 0.8 1.5 1.8 10.1 1.1 22.5 14.4 22.5 12.1 3.8 5.9 26.6 5.7 19.7 13.7 29.5 3.1 147.8 12.4 10.1 44.5 24.6 14.6 8.2 0.5 28.9 1.1 31.1 0.0 3.9 0.1 0.7 3.4 0.3 0.8 3.7 0.8 2.1 0.4 16.7 4.8 0.6 0.8 0.5 1.9 4.1 4.0 26.8 31.0 30.9 36.7 23.5 31.4 32.1 27.0 35.9 35.1 25.3 42.9 221.6 134.6 149.8 59.4 30.0 103.9 98.0 60.6 71.2 56.5 202.4 81.3 81.5 124.4 105.4 68.0 35.5 77.9 33.1 34.5 7.9 85.3 12.3 76.4 227.6 256.2 19.8 41.1 25.7 62.0 75.5 285.5 59.1 580.3 32.9 58.6 808.5 219.8 56.0 16.8 70.0 34.1 46.8 93.7 99.1 16.7 105.9 60.3 80.0 188.3 45.8 190.8 7.2 75.4 64.2 80.8 35.6 130.5 100.6 163.9 33.6 52.2 80.3 39.3 98.6 158.7 150.3 54.4 38.6 44.9 83.5 101.8 75.5 228.7 17.1 106.1 IL7 IL-7 ENSG00000104432 "Interleukin 7" P13232 8 78675743-78805523 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 108.8;Late spermatids: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.7;naive B-cell: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.6;HDLM-2: 15.4;HEL: 18.2;HMC-1: 25.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019590 Approved "Secreted to blood" NA NA 60700 "Cluster 19: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA019590: AB_10794621" "unprognostic (3.19e-3)" "unprognostic (1.44e-1)" "unprognostic (9.57e-3)" "unprognostic (5.45e-2)" "unprognostic (9.37e-3)" "unprognostic (3.36e-1)" "unprognostic (1.71e-1)" "unprognostic (1.65e-2)" "unprognostic (2.28e-1)" "unprognostic (2.47e-1)" "unprognostic (3.02e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (6.55e-2)" "unprognostic (2.11e-4)" 2.3 1.2 0.2 4.1 0.3 2.1 1.5 0.4 0.2 2.3 0.3 5.1 6.7 1.1 0.3 3.5 4.8 3.1 0.6 0.3 0.5 1.4 4.2 3.3 8.7 0.6 0.4 0.9 1.0 0.0 0.5 0.3 0.5 1.8 4.4 0.7 1.1 0.9 0.1 8.8 8.7 1.1 0.4 3.5 3.8 1.7 1.2 0.8 1.3 0.1 4.2 2.8 1.5 0.2 0.3 0.0 0.1 0.0 0.4 0.4 0.0 1.4 1.4 1.3 1.9 0.0 7.6 0.1 0.0 4.4 4.5 4.2 0.1 0.0 0.0 15.4 0.0 18.2 0.6 2.1 0.1 0.1 25.4 1.3 0.0 0.2 0.6 4.9 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.1 0.0 5.4 3.2 0.0 2.4 2.6 0.3 0.2 0.0 0.1 0.0 0.2 0.8 0.9 0.0 2.0 0.3 0.0 0.0 3.4 0.0 1.9 5.2 0.3 0.0 0.4 0.2 0.0 9.7 1.0 1.0 2.2 8.7 0.2 0.3 0.0 0.5 0.8 0.3 7.3 0.6 0.2 0.3 0.4 0.2 0.3 0.5 0.6 0.4 0.5 0.4 1.2 0.2 0.6 0.0 3.6 5.9 12.2 6.0 3.2 1.2 10.8 0.1 1.3 0.9 0.7 5.7 2.4 1.8 0.0 0.0 1.3 7.8 9.8 1.2 108.8 22.9 0.8 4.9 3.0 10.5 16.0 5.1 0.0 2.5 11.2 0.6 0.0 0.1 1.8 2.4 0.9 0.0 11.0 6.2 2.0 1.0 3.3 145.5 0.6 1.9 0.0 1.0 3.4 2.0 0.0 20.1 6.0 2.6 11.5 1.2 1.0 1.2 12.4 9.5 24.2 0.4 0.0 2.2 0.5 2.3 0.9 5.2 6.5 0.0 1.6 0.1 4.6 1.7 IL7R "CD127, IL7RA" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 183.7" "Group enriched" "Detected in many" 4 "monocytes: 271.8;T-cells: 973.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 102.1;MAIT T-cell: 369.5;memory CD4 T-cell: 213.8;memory CD8 T-cell: 151.1;naive CD4 T-cell: 179.5;naive CD8 T-cell: 124.6;NK-cell: 113.2" "Group enriched" "Detected in all" 33 "NK-cells: 113.2;T-cells: 369.5" "Cell line enhanced" "Detected in many" "BJ: 99.8;BJ hTERT+ SV40 Large T+: 87.7;fHDF/TERT166: 187.7;HBF TERT88: 168.3;REH: 406.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550" Supported "Plasma membrane" "Intracellular and membrane" NA NA 610000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "CAB010215: AB_673727, HPA067550: " "unprognostic (2.93e-3)" "unprognostic (3.38e-2)" "unprognostic (3.82e-3)" "unprognostic (5.58e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-3)" "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" "unprognostic (9.29e-3)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (5.64e-2)" "unprognostic (3.27e-3)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" 11.2 14.4 1.5 137.6 1.8 14.0 20.4 7.4 2.7 12.0 1.0 17.3 15.0 3.9 1.6 11.0 5.7 32.4 2.2 2.0 2.5 4.5 12.5 63.9 139.4 1.8 0.5 2.2 5.3 0.8 1.7 2.9 1.6 8.7 20.4 0.9 3.3 3.1 4.1 3.8 56.8 5.6 0.6 70.1 34.1 4.7 4.4 183.7 7.6 1.7 123.0 48.0 7.1 6.2 0.6 0.4 0.7 0.4 0.7 0.6 0.6 99.8 50.6 87.7 51.3 0.5 0.6 9.6 0.3 187.7 15.9 16.0 0.2 6.0 168.3 8.6 1.1 3.2 10.3 0.0 1.5 0.6 7.2 1.6 0.0 18.7 4.3 2.4 2.6 0.7 0.7 0.9 71.3 0.2 2.3 1.0 0.3 0.3 4.6 406.2 5.2 0.6 0.0 5.3 0.4 0.2 15.9 1.7 0.2 0.3 0.6 0.4 7.0 34.5 58.4 14.8 13.4 0.6 0.2 10.4 17.4 9.2 27.8 4.3 1.6 1.0 102.1 1.2 369.5 1.5 213.8 151.1 0.7 2.1 179.5 124.6 7.3 113.2 1.5 1.8 39.7 87.7 1.5 1.8 7.4 2.7 2.0 2.5 1.8 0.5 1.6 0.6 4.4 6.2 8.9 16.0 16.0 0.0 47.4 11.6 2.7 0.0 5.2 0.0 8.6 6.1 4.9 0.0 2.5 0.0 0.0 0.2 136.0 0.6 0.0 1.0 0.1 1.1 0.4 13.2 0.0 16.4 0.0 2.0 0.2 11.6 53.5 1.2 19.6 0.2 13.2 4.4 10.6 0.0 0.0 0.5 0.0 10.6 98.5 0.8 0.0 58.8 21.4 2.8 271.8 0.0 11.3 0.0 0.0 0.1 1.4 0.0 93.5 1.4 0.0 0.8 5.8 0.0 0.0 5.5 7.9 0.2 0.1 1.5 10.4 0.3 973.8 0.4 0.4 3.5 IL9 "HP40, IL-9, P40" ENSG00000145839 "Interleukin 9" P15248 5 135892246-135895841 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 279 "HDLM-2: 43.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 11000 "Cluster 44: HDLM-2 - Immune response" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.2 0.1 0.1 0.1 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ILDR1 "DFNB42, MGC50831" ENSG00000145103 "Immunoglobulin like domain containing receptor 1" Q86SU0 3 121987323-122022247 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 15.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Club cells: 14.7;Collecting duct cells: 20.2;Cytotrophoblasts: 16.6;Distal enterocytes: 17.5;Glandular and luminal cells: 13.5;Respiratory ciliated cells: 13.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 4 "B-cells: 1.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 6.3;HDLM-2: 8.2;MCF7: 5.1;RT4: 7.5;T-47d: 5.3;U-266/70: 6.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA018207 Approved "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA018207: AB_1851742" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (9.24e-2)" "unprognostic (4.46e-3)" "unprognostic (9.73e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-2)" "unprognostic (2.80e-2)" "unprognostic (2.00e-1)" "unprognostic (2.04e-1)" "unprognostic (7.78e-2)" "unprognostic (2.37e-1)" "prognostic favorable (5.79e-9)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (3.25e-3)" "unprognostic (2.21e-2)" 0.0 0.7 0.2 1.3 0.1 0.3 2.9 0.2 0.3 11.7 0.1 8.2 3.3 1.0 12.8 3.8 5.1 3.3 0.0 0.1 0.0 6.5 0.2 2.9 1.1 0.1 0.1 0.0 6.7 15.7 2.4 1.8 0.1 6.9 7.2 0.2 8.0 10.6 0.1 1.2 2.4 0.3 0.0 0.6 0.8 0.6 0.1 0.8 7.3 0.0 2.2 2.2 1.1 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 6.3 1.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 8.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 5.1 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.4 2.8 7.5 0.2 0.0 0.0 0.7 0.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 6.1 1.4 1.1 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.2 1.1 0.1 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.2 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 12.8 7.4 0.3 1.3 0.0 0.8 7.5 0.0 0.0 4.2 2.4 0.7 4.3 14.7 20.2 0.0 16.6 0.1 17.5 1.9 7.5 0.2 6.3 1.6 0.1 3.5 0.0 0.5 3.7 0.5 0.1 1.1 13.5 0.0 0.2 0.0 0.1 1.2 0.0 0.5 7.9 8.2 0.6 0.0 0.0 0.0 0.3 1.8 1.9 0.0 0.0 0.0 0.0 0.2 2.6 8.9 0.0 2.1 2.2 2.5 2.1 13.7 0.0 0.0 0.0 0.6 0.0 0.1 5.9 0.6 5.1 0.1 0.0 7.8 3.5 ILDR2 C1orf32 ENSG00000143195 "Immunoglobulin like domain containing receptor 2" Q71H61 1 166895711-166975540 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;retina: 10.6;testis: 8.8" "Cell type enhanced" "Detected in some" "Astrocytes: 22.9;Excitatory neurons: 45.0;Muller glia cells: 89.1;Oligodendrocyte precursor cells: 96.0" "Cancer enriched" "Detected in some" 5 "glioma: 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.8;JURKAT: 5.7;MOLT-4: 4.3;U-2 OS: 9.6;U-251 MG: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012545, HPA012815" Uncertain Approved "Plasma membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA012545: AB_2126894, HPA012815: " "unprognostic (9.14e-2)" "unprognostic (5.05e-2)" "unprognostic (8.27e-2)" "unprognostic (2.16e-1)" "unprognostic (5.89e-2)" "unprognostic (5.33e-2)" "unprognostic (2.89e-5)" "unprognostic (2.09e-1)" "unprognostic (8.55e-2)" "unprognostic (4.51e-2)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (9.17e-2)" "unprognostic (5.87e-3)" "unprognostic (4.92e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" 0.3 0.3 7.0 0.2 6.7 0.5 0.0 0.0 8.0 0.1 0.0 1.6 0.1 0.1 0.4 0.1 0.2 0.3 1.4 8.7 4.4 2.8 0.4 0.4 0.2 0.0 4.8 0.1 0.1 0.0 1.4 0.1 0.2 0.8 0.3 10.6 0.1 1.1 0.1 0.0 0.2 0.7 0.0 0.1 0.1 8.8 12.8 1.1 0.1 0.2 0.2 0.3 0.1 1.5 0.0 0.0 7.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.8 1.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.2 0.0 2.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.2 0.0 4.3 0.0 2.7 0.1 0.0 0.0 0.2 0.5 0.5 0.1 1.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.0 9.6 0.0 5.4 1.8 0.0 0.4 1.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 6.7 0.0 8.0 8.7 4.4 0.0 4.8 0.2 0.0 12.8 1.5 0.0 0.0 0.0 22.9 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 4.3 0.0 0.6 0.0 6.2 0.0 2.0 0.2 0.0 0.1 12.7 0.0 0.1 0.2 1.2 0.0 45.0 0.2 0.3 0.6 0.0 0.1 0.0 1.7 0.4 1.6 0.1 1.7 17.6 0.0 0.0 0.0 0.0 18.8 0.6 0.2 0.0 5.6 0.6 89.1 0.0 96.0 16.5 0.1 0.2 0.0 0.9 0.0 0.0 4.9 0.0 8.8 0.0 8.8 0.5 4.8 2.0 0.0 0.0 0.3 0.5 0.1 0.3 0.0 ILVBL "209L8, AHAS, FLJ39061, HACL1L, ILV2H, MGC1269, MGC19535" ENSG00000105135 "IlvB acetolactate synthase like" A1L0T0 19 15114984-15125786 "Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 148.2;Syncytiotrophoblasts: 253.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067682 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Golgi apparatus, Vesicles" "HPA067682: AB_2685885" "unprognostic (5.68e-2)" "unprognostic (1.86e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (8.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.04e-2)" "unprognostic (2.53e-1)" "unprognostic (3.83e-1)" "unprognostic (5.60e-2)" "unprognostic (1.77e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.91e-8)" "unprognostic (4.65e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (2.40e-1)" 29.7 45.5 22.7 13.9 27.5 15.5 27.5 30.9 25.1 29.7 32.8 46.2 50.1 24.3 14.4 40.9 22.6 25.5 73.7 21.4 25.5 41.6 56.8 19.2 15.5 29.2 25.3 28.3 42.5 65.8 34.4 19.2 26.3 24.2 18.6 13.8 27.7 23.2 18.7 43.4 43.7 13.7 24.8 17.6 41.1 25.5 25.2 10.5 48.0 25.0 10.6 28.5 30.6 32.3 68.8 41.0 34.4 40.7 43.8 29.7 39.6 31.6 42.2 37.2 47.5 65.5 162.1 29.7 61.1 34.2 22.3 50.6 20.9 38.5 10.8 27.5 41.1 43.7 41.3 72.4 70.1 37.2 37.0 44.6 43.9 21.7 28.3 30.4 35.0 29.6 17.9 37.6 29.3 159.0 24.9 29.6 31.9 54.9 58.8 36.0 31.1 46.5 32.3 33.6 28.4 38.3 18.8 81.2 62.1 13.2 37.2 31.2 37.7 55.9 30.7 71.0 45.1 26.1 29.2 15.1 35.9 35.8 43.1 22.7 22.2 5.5 21.1 31.8 24.0 11.9 17.7 22.0 26.3 12.9 22.9 23.6 2.5 23.7 30.3 19.1 20.2 23.3 22.7 27.5 30.9 25.1 21.4 25.5 29.2 25.3 26.3 24.8 25.2 32.3 28.0 25.6 11.7 18.3 12.7 12.7 26.8 53.8 22.2 95.3 18.0 14.9 36.1 62.9 43.0 25.8 27.1 84.2 15.8 67.8 19.6 48.4 6.2 9.9 13.4 23.2 44.4 12.6 4.9 50.6 148.2 21.4 40.2 13.0 11.4 29.0 26.7 59.3 43.2 18.5 8.3 60.6 28.5 12.1 9.5 6.5 25.7 15.8 83.6 5.6 6.8 48.0 7.2 9.0 15.7 32.3 68.4 19.9 17.2 18.6 123.0 50.4 26.1 36.8 19.7 14.7 21.2 20.3 20.8 25.0 16.2 253.4 11.8 48.2 73.2 23.4 IMMP2L "IMMP2L-IT1, IMP2" ENSG00000184903 "Inner mitochondrial membrane peptidase subunit 2" Q96T52 7 110662644-111562517 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 247.8;Distal tubular cells: 160.4;Excitatory neurons: 365.4;Inhibitory neurons: 373.9;Microglial cells: 455.3;Oligodendrocyte precursor cells: 273.9;Oligodendrocytes: 233.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026711 Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA026711: AB_1851760" "unprognostic (2.55e-2)" "unprognostic (1.40e-2)" "unprognostic (4.29e-1)" "unprognostic (1.04e-1)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.89e-5)" "unprognostic (5.64e-3)" "unprognostic (1.00e-1)" "unprognostic (4.17e-1)" "unprognostic (5.68e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.89e-3)" "unprognostic (1.32e-1)" "unprognostic (6.65e-2)" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" 19.2 14.2 10.4 5.1 12.5 5.2 15.7 9.6 11.7 12.4 14.2 14.6 7.6 15.3 11.9 8.0 16.0 8.5 13.1 11.9 12.2 34.0 25.7 8.1 7.5 11.3 11.3 19.5 12.1 20.1 8.0 9.0 11.3 19.0 8.2 9.2 11.1 21.1 27.3 10.2 12.9 14.2 10.9 8.4 11.8 9.9 11.4 8.9 23.5 25.1 7.5 12.5 10.5 13.1 17.5 10.3 6.1 25.1 15.8 16.0 10.7 11.8 11.9 7.7 8.1 5.1 19.8 28.4 31.4 10.2 14.3 9.6 6.6 23.6 12.7 17.9 6.7 9.7 44.2 14.0 24.2 18.2 1.1 27.9 30.7 3.3 21.4 35.0 10.2 26.2 32.0 21.4 5.9 12.3 24.4 20.3 6.0 33.2 15.8 5.1 50.0 15.0 28.0 7.3 7.0 22.1 5.1 23.8 67.3 17.2 9.6 10.4 6.5 11.8 12.3 11.9 14.4 12.2 3.5 17.4 12.9 8.4 63.1 15.9 9.1 2.9 10.5 11.9 19.4 28.5 18.3 12.3 17.0 38.7 25.0 17.6 0.5 47.0 17.3 21.3 12.4 8.1 10.4 12.5 9.6 11.7 11.9 12.2 11.3 11.3 11.3 10.9 11.4 13.1 22.3 19.2 13.2 247.8 20.4 32.9 34.4 41.4 39.9 11.3 35.3 39.4 19.5 15.7 23.9 47.8 8.4 22.4 11.9 3.1 160.4 30.1 8.4 10.4 12.6 15.3 19.3 21.9 365.4 8.1 27.1 19.5 12.8 12.0 3.8 11.3 11.7 23.8 11.7 8.4 373.9 7.0 28.5 4.9 14.1 5.6 49.4 6.1 21.4 455.3 10.1 16.3 1.0 273.9 233.7 10.8 6.8 35.0 9.2 36.2 25.5 66.8 13.3 15.6 13.1 19.5 46.7 24.2 12.8 28.0 26.6 16.3 12.6 18.7 11.7 22.1 IMP4 "BXDC4, MGC19606" ENSG00000136718 "IMP U3 small nucleolar ribonucleoprotein 4" Q96G21 2 130342877-130347967 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 303.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066222, HPA066673" Enhanced Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli "HPA066222: AB_2685638, HPA066673: AB_2685701" "unprognostic (8.26e-2)" "unprognostic (5.10e-2)" "unprognostic (3.00e-1)" "unprognostic (2.55e-1)" "unprognostic (3.70e-3)" "unprognostic (2.18e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (1.33e-1)" "unprognostic (1.67e-1)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (1.11e-1)" "unprognostic (1.28e-2)" "unprognostic (5.08e-2)" "unprognostic (4.47e-2)" "unprognostic (1.09e-1)" "unprognostic (6.10e-2)" 29.2 25.4 14.3 20.6 16.1 20.8 25.6 15.3 16.8 14.8 11.4 22.4 19.9 18.0 6.3 20.5 13.9 12.4 37.5 13.7 16.5 19.9 47.7 17.7 24.5 18.5 18.3 12.1 45.4 12.9 11.4 11.5 16.6 15.4 7.2 3.6 31.8 12.0 70.1 18.7 18.5 11.7 15.9 17.3 24.5 11.8 18.1 7.2 11.4 25.5 12.2 23.3 15.7 16.9 88.7 87.1 11.1 59.2 13.5 22.7 61.5 60.8 30.2 54.1 39.8 184.5 55.0 303.2 71.5 30.2 36.0 56.6 64.5 66.5 25.9 64.2 66.0 100.3 33.2 143.8 70.7 99.7 51.8 28.1 48.0 71.9 37.6 10.9 38.5 68.7 103.1 58.8 26.5 157.0 63.2 57.1 85.4 53.0 106.3 73.1 39.4 134.4 27.0 61.0 57.9 51.8 41.3 124.0 62.9 7.2 52.7 47.0 47.5 69.8 74.3 75.2 109.0 77.5 87.8 235.4 56.5 56.5 98.9 12.3 72.7 23.9 71.5 82.6 66.1 115.9 62.7 62.6 84.1 99.7 64.8 64.6 8.0 90.8 79.4 91.5 68.9 89.2 14.3 16.1 15.3 16.8 13.7 16.5 18.5 18.3 16.6 15.9 18.1 16.9 41.4 16.0 24.8 3.3 65.5 106.6 79.3 67.0 58.6 21.9 49.5 46.4 53.7 58.6 46.5 44.1 4.2 63.6 52.3 43.4 101.8 96.4 24.2 19.6 27.3 48.6 54.5 32.6 4.2 110.3 100.5 43.2 45.9 22.3 46.3 26.8 29.6 89.1 76.5 16.8 4.8 49.8 52.9 36.5 54.0 69.9 30.7 37.5 78.2 1.0 66.1 18.9 33.0 4.5 5.0 83.7 54.2 25.6 82.4 148.6 55.5 144.6 22.9 25.5 26.3 43.7 51.6 32.7 48.3 57.6 110.4 49.3 45.9 62.1 77.5 79.2 IMPA2 ENSG00000141401 "Inositol monophosphatase 2" O14732 18 11981025-12030877 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 359.1;skeletal muscle: 257.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 440.3;Extravillous trophoblasts: 272.2;Proximal tubular cells: 498.6;Squamous epithelial cells: 202.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 26.0;neutrophil: 31.3" "Group enriched" "Detected in many" 11 "dendritic cells: 9.0;granulocytes: 31.3;monocytes: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 258.2;OE19: 299.8;SiHa: 155.1" "Low region specificity" "Detected in all" HPA029561 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Mitochondria "HPA029561: AB_10601932" "unprognostic (1.16e-1)" "unprognostic (1.28e-2)" "unprognostic (4.76e-3)" "unprognostic (2.50e-2)" "unprognostic (4.25e-2)" "unprognostic (3.25e-3)" "unprognostic (4.26e-3)" "unprognostic (4.08e-2)" "unprognostic (1.87e-1)" "unprognostic (1.96e-2)" "unprognostic (4.56e-2)" "unprognostic (4.24e-3)" "prognostic favorable (0.00e+0)" "unprognostic (1.95e-1)" "unprognostic (1.19e-1)" "unprognostic (2.08e-2)" "unprognostic (3.35e-2)" 19.8 11.1 2.5 12.3 3.2 31.5 14.8 1.8 4.4 31.0 5.3 50.0 22.4 16.2 1.7 131.2 16.3 19.9 29.5 2.5 2.4 129.4 47.4 23.2 5.7 2.2 2.4 7.8 359.1 5.3 11.1 22.0 2.1 13.7 30.7 0.8 31.0 5.9 257.1 150.0 29.2 15.6 2.3 19.0 53.7 2.9 2.6 5.0 17.4 89.8 7.3 61.0 50.8 2.3 29.3 41.7 11.3 20.4 14.1 10.5 258.2 7.2 18.4 2.9 4.2 35.4 21.7 6.1 17.4 10.1 24.1 19.8 13.2 6.9 0.8 33.5 22.5 0.0 56.0 30.6 8.3 47.5 2.3 23.9 36.3 10.0 5.2 8.5 3.9 30.7 7.4 0.0 10.7 31.8 19.4 27.1 40.5 299.8 42.7 36.0 29.6 28.6 122.1 15.6 15.0 0.3 155.1 35.8 16.2 14.5 33.3 58.5 0.0 5.6 11.5 73.7 7.3 24.5 66.3 17.9 24.0 31.7 9.6 9.4 11.4 26.0 0.7 8.7 0.3 1.5 0.7 0.2 9.0 0.3 0.3 0.5 31.3 0.1 5.8 6.7 1.1 3.1 2.5 3.2 1.8 4.4 2.5 2.4 2.2 2.4 2.1 2.3 2.6 2.3 9.2 19.2 32.7 17.6 7.8 105.5 22.7 32.1 159.4 0.7 16.8 20.2 11.6 72.9 16.1 22.0 0.0 52.5 5.8 72.9 440.3 83.4 2.8 5.7 20.2 6.9 17.5 15.3 4.7 110.6 272.2 16.1 65.2 30.4 2.5 13.4 10.0 66.8 42.5 0.0 1.8 90.2 65.1 37.7 17.0 7.1 4.7 34.2 14.2 5.6 25.5 22.3 2.1 0.5 0.5 56.1 50.1 3.8 8.6 42.9 36.9 498.6 12.3 1.0 105.2 16.0 27.6 0.8 10.1 202.1 141.4 106.3 6.1 14.0 84.4 52.8 IMPG1 "GP147, IPM150, SPACR" ENSG00000112706 "Interphotoreceptor matrix proteoglycan 1" Q17R60 6 75921114-76072678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 267 "retina: 670.7" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 673.5;Rod photoreceptor cells: 694.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HaCaT: 1.2" "Region enriched" "Detected in single" 4 "basal ganglia: 3.3" "Not detected" "Not detected" "HPA027142, HPA030332, HPA030333" Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA027142: AB_2672132, HPA030332: AB_2673432, HPA030333: AB_2673433" "unprognostic (6.65e-2)" "unprognostic (4.13e-2)" "unprognostic (1.20e-1)" "unprognostic (8.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.49e-3)" "unprognostic (5.97e-2)" "unprognostic (3.56e-3)" "unprognostic (1.89e-2)" "unprognostic (2.20e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-3)" "unprognostic (2.84e-1)" "unprognostic (1.73e-2)" "unprognostic (2.09e-1)" "unprognostic (6.01e-2)" "unprognostic (1.96e-2)" 0.3 0.1 0.5 0.0 2.5 0.0 0.5 1.0 1.4 0.3 0.8 0.3 1.0 0.2 0.0 0.2 0.1 0.4 0.2 0.5 0.4 0.6 0.2 0.6 0.1 0.6 0.6 0.1 1.8 0.0 0.3 0.2 0.6 0.2 0.0 670.7 0.5 0.0 0.2 1.4 0.8 0.0 0.1 0.2 0.3 0.3 0.6 0.1 0.4 0.0 0.0 0.2 0.3 1.6 0.6 0.0 0.8 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 0.1 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.5 1.0 1.4 0.5 0.4 0.6 0.6 0.6 0.1 0.6 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 53.2 0.0 0.0 0.2 0.0 0.0 0.0 673.5 0.2 0.0 0.0 3.9 0.0 1.9 0.2 0.0 3.0 0.0 0.0 1.6 0.0 9.4 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 30.3 0.9 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 85.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 694.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 INHA ENSG00000123999 "Inhibin subunit alpha" P05111 2 219569162-219575711 "Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 75.6;ovary: 104.4;testis: 95.3" "Cell type enhanced" "Detected in some" "Granulosa cells: 254.3;Syncytiotrophoblasts: 331.0;Theca cells: 75.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.5;HEL: 4.5;SK-BR-3: 9.9;SuSa: 4.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB000047, HPA019141, HPA048834" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Golgi apparatus" "CAB000047: AB_322161, HPA019141: AB_1851789, HPA048834: " "unprognostic (8.90e-3)" "unprognostic (2.91e-2)" "unprognostic (2.82e-1)" "unprognostic (7.55e-2)" "unprognostic (1.02e-3)" "unprognostic (1.45e-1)" "unprognostic (3.57e-1)" "unprognostic (9.61e-3)" "unprognostic (4.15e-3)" "unprognostic (6.71e-2)" "unprognostic (3.73e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (4.03e-5)" "unprognostic (4.85e-2)" "unprognostic (7.20e-2)" "unprognostic (1.93e-1)" "unprognostic (4.43e-2)" 1.2 75.6 3.4 0.2 3.7 0.1 1.4 2.7 4.8 2.0 2.2 0.9 0.2 2.0 2.2 0.8 3.0 0.4 16.3 3.5 3.2 3.1 0.7 0.8 0.1 3.4 2.9 104.4 12.3 0.7 6.6 11.3 3.5 3.1 0.0 1.9 1.5 1.1 0.8 2.1 0.4 0.4 2.5 0.4 0.7 95.3 3.4 0.0 3.3 0.0 0.0 1.0 1.8 3.0 0.4 0.2 0.0 1.9 0.6 0.1 3.5 0.3 0.2 0.5 0.2 0.3 3.2 0.0 0.2 0.7 0.5 2.0 0.2 0.5 0.0 0.0 0.6 4.5 1.8 2.4 0.3 0.0 0.0 0.6 0.8 0.0 0.5 1.4 0.0 0.0 2.8 0.0 0.0 2.3 0.0 0.1 1.2 0.1 0.9 0.1 0.2 0.0 0.5 0.2 0.3 0.8 1.1 9.9 0.3 4.9 0.5 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.7 2.7 4.8 3.5 3.2 3.4 2.9 3.5 2.5 3.4 3.0 0.1 0.0 0.0 5.9 0.0 0.0 0.1 0.8 0.0 2.7 0.3 0.3 2.2 0.0 0.1 7.3 2.1 11.8 0.0 0.0 0.0 2.8 0.8 0.5 0.5 0.2 0.0 0.0 5.9 8.9 35.5 1.2 0.0 0.5 0.0 254.3 0.7 0.1 2.6 6.7 6.9 0.0 0.0 0.3 0.0 5.0 4.1 0.2 0.0 0.0 0.0 3.7 0.0 1.0 0.4 2.1 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 1.5 3.4 0.6 0.0 0.0 331.0 0.0 75.6 0.0 0.0 INHBA ENSG00000122641 "Inhibin subunit beta A" P08476 7 41667168-41705834 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 21.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 94.4;Langerhans cells: 68.0;Leydig cells: 137.6;Smooth muscle cells: 218.3;Syncytiotrophoblasts: 178.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 75.9;hTEC/SVTERT24-B: 227.0;hTERT-HME1: 92.9;hTERT-RPE1: 139.2;TIME: 120.1;U-138 MG: 174.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 210000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (4.11e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (4.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.18e-2)" "prognostic unfavorable (4.34e-4)" "unprognostic (2.05e-2)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.44e-1)" "unprognostic (1.31e-1)" "unprognostic (1.23e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (7.91e-8)" "unprognostic (6.22e-3)" "unprognostic (1.11e-2)" "unprognostic (3.25e-2)" "unprognostic (3.18e-3)" 2.3 1.5 2.1 5.1 2.0 10.4 0.9 2.3 7.8 1.5 0.7 1.0 0.8 17.3 3.7 2.1 1.2 21.6 5.4 8.7 3.3 2.8 9.5 11.0 1.2 4.3 8.1 6.8 0.6 0.5 0.5 10.9 3.4 3.2 0.6 2.3 5.4 5.0 0.5 2.0 0.5 4.3 4.5 0.5 0.8 1.7 3.0 0.2 1.2 4.6 0.4 10.3 1.1 3.4 4.2 0.0 0.4 0.1 3.3 7.1 0.0 18.2 1.9 9.9 3.3 0.0 0.4 0.0 1.1 6.9 11.6 15.3 0.0 75.9 9.6 5.1 0.0 0.0 0.0 0.0 13.9 0.0 0.2 7.0 4.2 227.0 92.9 139.2 8.2 0.0 0.5 0.0 23.0 0.2 0.0 0.3 1.5 0.0 10.5 0.0 0.0 0.0 0.0 0.1 0.1 5.7 11.1 0.6 0.0 6.2 0.1 0.2 120.1 174.7 49.7 18.9 19.0 0.0 0.0 0.0 6.7 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 2.1 2.0 2.3 7.8 8.7 3.3 4.3 8.1 3.4 4.5 3.0 3.4 0.7 3.2 15.7 0.0 0.9 17.3 10.8 13.5 2.2 0.1 3.5 6.5 6.0 0.0 4.4 0.0 0.0 1.4 0.3 0.1 0.0 23.6 0.6 1.4 4.1 5.9 0.0 0.0 2.4 2.0 4.6 42.0 0.0 2.6 7.6 94.4 0.7 18.5 1.5 0.0 0.2 0.2 4.1 1.4 68.0 5.9 137.6 55.8 14.2 0.0 27.0 16.1 0.0 4.0 0.3 11.1 0.1 23.3 0.0 12.5 0.0 0.1 2.8 1.3 0.0 4.9 218.3 0.7 0.3 1.4 8.9 178.4 1.7 18.8 0.2 2.3 INHBB ENSG00000163083 "Inhibin subunit beta B" P09529 2 120346136-120351803 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 52.5;breast: 43.3" "Group enriched" "Detected in many" 7 "Adipocytes: 200.5;Granulosa cells: 653.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 44.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 47.6;ASC diff: 63.1;BJ hTERT+ SV40 Large T+ RasG12V: 38.5;MCF7: 58.4;PC-3: 91.7;SK-BR-3: 163.4;T-47d: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 130000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.80e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.26e-2)" "unprognostic (4.26e-2)" "unprognostic (3.61e-3)" "unprognostic (2.13e-2)" "unprognostic (5.52e-2)" "unprognostic (6.99e-2)" "unprognostic (3.59e-1)" "unprognostic (1.59e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.57e-3)" "unprognostic (4.14e-1)" "prognostic favorable (1.02e-4)" "unprognostic (1.76e-2)" 52.5 3.7 5.6 0.9 5.5 0.2 43.3 8.0 4.0 6.9 3.4 3.4 1.3 7.4 2.6 2.5 6.2 2.5 6.4 3.9 4.8 4.3 20.2 4.4 1.1 9.7 7.4 2.5 4.2 6.3 8.0 1.2 6.0 8.2 0.3 1.0 16.4 0.8 10.4 17.1 2.4 2.2 6.2 0.5 3.6 17.1 7.9 0.4 20.9 2.4 0.7 8.2 6.4 4.2 24.5 47.6 0.2 0.0 63.1 4.9 0.0 3.3 3.8 20.7 38.5 1.0 0.0 0.0 8.3 1.2 0.1 0.1 3.7 0.0 28.9 0.1 0.8 0.0 0.0 1.2 1.0 0.0 0.1 2.6 3.5 0.7 0.0 0.3 0.4 0.0 0.0 0.0 0.1 58.4 0.0 0.1 0.0 4.7 91.7 0.0 0.0 1.2 5.6 0.0 5.4 0.0 0.2 163.4 0.0 0.0 39.2 0.5 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.6 5.5 8.0 4.0 3.9 4.8 9.7 7.4 6.0 6.2 7.9 4.2 200.5 3.2 2.2 8.1 0.2 4.0 2.2 5.5 0.0 0.1 53.7 24.4 0.7 8.6 9.2 1.8 25.0 0.1 0.7 0.1 0.0 0.4 0.6 9.2 1.6 24.3 0.0 2.7 0.1 0.0 0.2 9.8 0.0 12.5 0.0 653.3 24.7 19.4 0.1 0.0 1.3 0.0 8.2 1.3 6.6 3.6 11.8 1.3 1.8 1.0 0.0 0.2 0.0 2.5 0.0 0.2 0.0 6.8 0.3 8.9 0.0 0.0 30.0 0.6 0.0 37.3 3.1 0.8 6.0 0.6 3.0 0.1 0.6 0.2 0.0 3.2 INHBC ENSG00000175189 "Inhibin subunit beta C" P55103 12 57434784-57452062 "Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 172 "liver: 165.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Hepatocytes: 5.7;Microglial cells: 1.0" "Cancer enriched" "Detected in single" 85 "liver cancer: 22.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 6.4;Karpas-707: 6.3;RH-30: 2.8;U-266/70: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050755 Approved Cytosol "Secreted to blood" NA NA 21000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA050755: " "unprognostic (5.26e-2)" "unprognostic (4.58e-1)" "unprognostic (3.43e-3)" "unprognostic (4.08e-3)" "unprognostic (3.76e-1)" "unprognostic (1.98e-2)" "unprognostic (1.03e-2)" "unprognostic (1.10e-1)" "unprognostic (1.34e-1)" "unprognostic (1.23e-1)" "unprognostic (6.10e-2)" "unprognostic (2.48e-2)" "unprognostic (1.68e-4)" "unprognostic (2.90e-2)" "unprognostic (1.52e-1)" "unprognostic (3.55e-3)" "unprognostic (5.05e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 165.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 1.0 0.0 0.2 0.0 6.4 0.0 0.4 0.0 0.1 0.0 0.1 0.4 0.0 0.0 1.6 0.0 6.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 2.8 0.5 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.7 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 INHBE "activin, MGC4638" ENSG00000139269 "Inhibin subunit beta E" P58166 12 57452323-57459280 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "liver: 148.4" "Cell type enriched" "Detected in single" 43 "Hepatocytes: 35.0" "Cancer enriched" "Detected in some" 27 "liver cancer: 34.4" "Region enhanced" "Detected in some" "cerebellum: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 50.8;Karpas-707: 79.1;RH-30: 36.9;U-266/70: 263.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016843, CAB034017" Enhanced Supported Vesicles "Secreted to blood" NA NA 3500000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles "CAB034017: AB_2233745, HPA016843: AB_1851796" "unprognostic (7.34e-2)" "unprognostic (6.73e-2)" "unprognostic (3.45e-1)" "unprognostic (4.69e-5)" "unprognostic (2.61e-1)" "unprognostic (2.50e-1)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.79e-3)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.66e-8)" "unprognostic (4.09e-3)" "unprognostic (1.56e-1)" "unprognostic (3.57e-2)" "unprognostic (7.52e-3)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.6 0.3 0.2 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.3 148.4 0.1 0.1 0.9 0.0 0.0 0.9 0.1 1.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 1.5 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.1 0.0 1.4 0.5 0.0 0.2 0.1 0.2 0.2 0.4 0.3 0.5 0.0 0.5 0.3 2.9 7.8 0.2 9.2 0.4 0.1 4.0 1.9 0.7 0.2 0.4 1.8 0.0 1.2 18.3 0.2 0.1 0.3 11.9 50.8 2.3 2.4 4.9 5.3 1.2 11.4 0.4 0.0 1.8 5.0 79.1 0.0 0.0 0.2 0.2 0.5 0.1 0.3 0.2 36.9 8.8 0.0 0.1 19.5 0.9 0.0 0.0 7.6 0.3 0.6 8.7 0.3 0.2 4.0 0.1 0.6 263.5 9.2 3.8 1.5 0.4 0.3 0.9 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.1 1.6 0.3 0.1 0.1 0.9 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 INIP "C9orf80, HSPC043, hSSBIP1, MISE, SOSS-C" ENSG00000148153 "INTS3 and NABP interacting protein" Q9NRY2 9 112683926-112718149 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020382 Approved Supported Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA020382: AB_1845840" "prognostic unfavorable (7.08e-4)" "unprognostic (1.67e-1)" "unprognostic (9.64e-2)" "unprognostic (2.35e-1)" "unprognostic (8.05e-2)" "unprognostic (8.56e-2)" "unprognostic (1.01e-2)" "unprognostic (6.29e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (1.11e-2)" "unprognostic (4.47e-3)" "prognostic favorable (2.00e-8)" "prognostic favorable (2.53e-4)" "unprognostic (2.28e-1)" "unprognostic (3.50e-2)" "unprognostic (1.26e-1)" 7.4 8.7 8.0 8.4 10.9 10.4 11.4 9.7 11.9 8.0 5.4 10.1 10.3 7.2 8.6 9.8 8.4 8.6 7.5 8.1 9.6 10.8 11.0 8.4 14.5 9.2 8.8 8.2 5.0 10.7 6.5 6.1 9.6 6.9 11.5 10.3 8.1 6.5 6.5 9.2 10.9 7.6 8.4 9.7 7.4 5.4 9.6 14.5 10.6 10.0 14.1 9.3 6.2 15.5 16.5 15.6 21.4 31.0 18.2 19.2 21.9 22.7 12.4 19.4 19.3 19.7 13.2 43.8 13.9 15.7 14.6 22.9 21.0 10.9 25.8 53.0 12.3 18.2 17.6 18.0 11.8 37.1 13.3 10.4 14.7 20.6 16.6 9.5 18.2 22.1 31.7 27.5 21.4 27.8 33.3 19.0 11.1 29.8 28.8 36.5 45.1 18.9 22.2 21.9 27.9 20.9 28.7 18.1 15.7 14.2 27.1 23.1 15.4 16.1 24.7 30.9 22.4 13.7 62.4 37.3 20.4 21.3 27.7 30.4 24.8 32.5 15.7 29.3 20.7 15.5 20.1 23.4 27.1 20.0 21.8 18.9 19.8 18.4 27.0 9.7 20.8 20.3 8.0 10.9 9.7 11.9 8.1 9.6 9.2 8.8 9.6 8.4 9.6 15.5 15.6 22.4 15.6 9.1 19.1 36.7 18.1 31.4 13.1 17.1 19.2 16.5 15.5 15.7 22.4 14.7 16.7 21.4 20.6 19.4 56.7 23.4 3.9 21.0 18.8 18.1 22.3 19.4 18.3 16.1 32.0 14.9 12.8 18.7 26.6 11.2 15.7 17.7 26.1 43.7 15.4 17.1 32.6 24.5 33.5 3.2 14.0 26.2 19.6 3.7 42.3 24.7 34.0 16.6 25.2 24.2 12.3 12.0 11.8 17.9 21.7 31.7 13.0 16.9 0.0 17.3 13.1 17.4 15.8 19.4 41.8 14.8 23.0 12.4 19.8 25.2 INPP5A 5PTASE ENSG00000068383 "Inositol polyphosphate-5-phosphatase A" Q14642 10 132537787-132783480 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 6.7" "Lineage enriched" "Detected in single" 28 "granulocytes: 6.7" "Low cell line specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 250.8" "Low region specificity" "Detected in all" HPA012285 Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Plasma membrane" "HPA012285: AB_1851802" "prognostic unfavorable (7.47e-4)" "unprognostic (2.38e-1)" "unprognostic (2.54e-1)" "unprognostic (1.68e-3)" "unprognostic (1.43e-1)" "unprognostic (3.25e-2)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (5.65e-2)" "unprognostic (4.35e-1)" "unprognostic (4.70e-2)" "unprognostic (1.70e-2)" "prognostic favorable (3.15e-4)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (8.91e-3)" "unprognostic (8.66e-2)" 22.5 16.9 26.8 12.0 85.5 9.5 17.3 56.9 30.4 29.6 10.9 54.2 19.2 49.5 19.5 29.6 30.7 15.2 75.0 20.4 21.3 14.1 14.6 25.1 8.4 20.5 37.7 19.5 12.8 12.2 14.7 28.8 20.4 24.5 16.7 16.9 13.5 23.6 75.4 22.9 23.4 42.1 17.5 13.9 27.6 22.9 50.5 6.8 14.1 50.3 7.3 35.5 22.7 27.0 35.4 13.7 22.6 21.9 33.8 23.7 18.4 36.4 27.9 23.3 15.4 32.6 14.0 3.1 13.7 38.8 15.1 19.5 24.8 15.2 27.9 10.8 14.4 5.1 17.3 44.7 24.3 12.9 11.9 16.0 14.9 15.0 28.2 18.6 16.3 6.6 7.6 18.2 12.6 28.3 3.6 40.9 10.5 21.0 24.3 7.6 14.9 5.6 19.4 19.9 5.4 18.5 18.3 26.5 22.6 20.5 17.2 30.4 13.7 14.9 17.2 20.1 21.6 3.6 18.4 11.0 14.4 8.6 6.5 6.7 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.3 26.8 85.5 56.9 30.4 20.4 21.3 20.5 37.7 20.4 17.5 50.5 27.0 14.7 9.6 19.7 14.7 4.5 5.4 4.4 1.9 0.0 10.5 7.1 5.3 10.1 4.3 6.4 7.3 0.0 3.9 5.0 24.8 0.0 6.5 12.3 2.8 22.8 10.0 6.1 3.2 33.5 9.2 3.7 5.6 6.6 5.9 8.8 8.6 15.0 17.9 2.9 8.4 25.2 9.9 2.0 7.2 12.0 17.0 7.2 6.9 1.8 19.7 4.1 9.6 0.0 18.1 29.2 12.1 11.5 11.7 2.5 6.5 13.8 4.3 2.5 5.2 6.6 6.5 24.3 6.3 7.3 2.8 5.8 2.5 2.7 10.7 13.9 8.6 INPPL1 SHIP2 ENSG00000165458 "Inositol polyphosphate phosphatase like 1" O15357 11 72223701-72239147 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Immunity" "Actin-binding, Hydrolase" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 344.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037601 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Golgi apparatus" "HPA037601: AB_10672281" "unprognostic (2.68e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.68e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (2.49e-2)" "unprognostic (3.54e-2)" "unprognostic (1.51e-2)" "unprognostic (1.64e-1)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (2.88e-1)" "unprognostic (1.99e-3)" "unprognostic (2.07e-1)" 45.2 56.4 39.0 34.4 43.4 51.3 44.7 41.3 40.5 63.8 47.3 87.5 35.9 56.1 18.2 34.6 61.3 33.7 73.6 33.2 42.5 60.0 36.6 61.8 36.8 53.9 43.2 68.6 55.7 36.4 60.5 39.7 45.8 68.7 23.3 14.9 53.8 39.5 116.6 31.4 57.1 33.4 45.0 66.1 60.8 24.2 48.8 19.3 67.7 43.0 23.2 59.9 43.4 41.2 28.7 62.1 71.5 49.8 35.4 41.1 122.5 118.9 61.2 80.6 49.6 84.3 72.2 79.5 125.6 101.7 57.8 106.7 60.4 37.6 28.0 101.9 59.1 84.8 344.5 31.9 68.1 56.1 176.7 58.2 39.1 78.0 31.4 100.5 44.2 29.3 59.7 34.7 45.1 78.8 42.1 224.9 67.7 20.7 93.7 185.0 161.0 18.2 94.8 48.6 33.8 48.6 133.9 85.1 182.8 36.6 88.8 106.0 74.5 86.4 96.7 129.9 43.1 94.5 17.5 80.1 24.7 51.7 47.2 2.5 3.5 3.3 1.9 2.0 1.7 0.9 1.6 1.3 2.4 1.0 1.1 1.6 2.3 2.2 3.6 1.8 1.5 1.8 39.0 43.4 41.3 40.5 33.2 42.5 53.9 43.2 45.8 45.0 48.8 41.2 13.9 3.2 12.8 47.0 8.1 7.1 4.9 10.8 14.2 1.7 20.3 17.3 13.6 11.5 11.7 12.9 27.1 27.9 9.1 28.3 1.9 11.6 1.5 14.6 16.3 11.2 22.7 5.7 2.6 12.5 15.4 10.8 24.5 25.5 7.6 21.0 8.9 12.5 21.7 10.1 2.2 16.4 18.3 27.6 16.2 2.1 9.9 29.8 10.6 18.7 17.6 16.8 14.4 15.1 6.1 14.9 17.5 13.9 7.8 7.8 15.2 16.2 10.2 17.2 6.6 12.9 14.5 1.4 4.9 6.7 4.8 32.4 11.6 10.1 21.8 5.4 INS "IDDM1, IDDM2" ENSG00000254647 Insulin P01308 11 2159779-2161221 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism" Hormone "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 135 "pancreas: 12983.6" "Cell type enriched" "Detected in some" 21 "Pancreatic endocrine cells: 1475.2" "Cancer enriched" "Detected in single" 7165 "pancreatic cancer: 1751.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "EFO-21: 268.3;U-2 OS: 376.2;U-698: 132.4" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 13 "midbrain: 1.3" "CAB000048, HPA004932, CAB012098, CAB053843" Enhanced "Secreted to blood" NA NA 437000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "CAB000048: , CAB012098: AB_300968, CAB053843: AB_620123, HPA004932: AB_1851816" "unprognostic (7.61e-2)" 19.2 4.0 0.1 0.2 0.1 49.8 0.6 0.0 0.0 0.7 0.0 12.8 1.5 1.4 0.0 1.8 0.3 3.7 5.6 0.1 0.1 40.7 1.4 1.7 5.4 0.2 0.4 2.6 12983.6 0.0 0.3 1.4 0.8 0.5 0.0 0.0 3.1 0.0 0.3 96.4 0.7 0.0 0.0 1.4 42.2 0.3 0.0 0.0 1.3 0.0 0.0 5.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 268.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 376.2 0.0 31.8 0.0 15.9 132.4 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 67.2 0.0 0.0 0.0 0.0 1475.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 INS-IGF2 ENSG00000129965 "INS-IGF2 readthrough" F8WCM5 11 2132538-2161209 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 48 "pancreas: 9.1" "Cell type enriched" "Detected in single" 11 "Hepatocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB019430 Enhanced "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 2: Hepatocytes - Metabolism" "CAB019430: AB_10691857" "unprognostic (1.33e-1)" "unprognostic (2.34e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 INSL3 "MGC119818, MGC119819, RLF, RLNL" ENSG00000248099 "Insulin like 3" P51460 19 17816512-17821574 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" Hormone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 409.3" "Cell type enriched" "Detected in some" 19 "Theca cells: 24080.8" "Cancer enriched" "Detected in many" 21 "testis cancer: 39.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Karpas-707: 5.7;PC-3: 2.6;SCLC-21H: 5.2;SH-SY5Y: 4.7" HPA028615 Enhanced "Secreted to blood" NA NA 566000 "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 52: Non-specific - Transcription" "HPA028615: AB_10600717" "unprognostic (3.25e-1)" "unprognostic (2.25e-4)" "unprognostic (3.50e-5)" "unprognostic (7.04e-2)" "unprognostic (1.74e-4)" "unprognostic (4.60e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.44e-1)" "unprognostic (1.73e-1)" "unprognostic (4.46e-1)" "unprognostic (4.93e-2)" "unprognostic (9.51e-10)" "unprognostic (6.80e-3)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (1.09e-5)" 0.5 1.6 1.2 4.8 1.3 1.8 0.5 2.3 1.5 0.1 1.3 0.5 1.5 0.3 0.8 0.6 0.8 0.4 0.2 1.4 1.5 0.5 0.4 0.9 2.9 1.2 1.3 29.6 0.2 0.0 0.2 0.3 1.4 0.6 0.0 0.1 0.6 0.0 0.2 0.3 1.7 0.0 1.2 5.2 0.8 409.3 1.5 0.5 0.3 0.4 1.2 0.4 0.3 1.3 0.2 0.6 0.1 0.5 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.1 1.1 0.1 1.4 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.5 0.0 0.2 0.0 0.0 1.2 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 1.0 0.2 1.1 0.0 1.1 2.6 0.9 0.0 0.1 0.1 0.3 5.2 4.7 0.0 1.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.0 0.4 2.1 0.1 0.1 1.3 0.0 0.4 0.2 0.0 0.7 0.4 0.7 0.0 0.9 0.9 0.1 1.1 0.7 1.0 2.2 0.5 0.1 0.1 0.8 0.5 1.2 1.3 2.3 1.5 1.4 1.5 1.2 1.3 1.4 1.2 1.5 1.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 2.3 0.0 0.0 0.1 6.8 0.0 0.1 3.4 0.0 0.0 0.3 0.0 0.4 42.3 0.0 0.0 0.0 0.9 0.4 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 257.1 1240.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 998.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 2.9 5.7 0.0 0.0 0.5 0.8 24080.8 0.0 0.0 INSL4 EPIL ENSG00000120211 "Insulin like 4" Q14641 9 5231419-5235304 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "placenta: 15.9" "Cell type enriched" "Detected in some" 10 "Syncytiotrophoblasts: 3575.7" "Cancer enhanced" "Detected in some" "lung cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "A549: 24.6" HPA065145 Approved Vesicles "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA065145: " "unprognostic (9.77e-2)" "unprognostic (2.02e-1)" "unprognostic (4.66e-1)" "unprognostic (7.74e-2)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 24.6 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.4 0.0 2.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 325.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 26.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 38.2 0.0 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3575.7 0.0 0.0 0.0 0.0 INSL5 ENSG00000172410 "Insulin like 5" Q9Y5Q6 1 66797741-66801256 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 106 "intestine: 128.9" "Cell type enriched" "Detected in some" 365 "Enteroendocrine cells: 8836.2" "Group enriched" "Detected in some" 5 "colorectal cancer: 1.2;prostate cancer: 0.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA030100, CAB033849" Enhanced "Secreted to blood" NA NA 38500000 "Cluster 37: Intestine - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB033849: AB_2264904, HPA030100: AB_10601915" "unprognostic (2.48e-1)" "unprognostic (4.41e-2)" "unprognostic (2.91e-1)" "unprognostic (1.18e-1)" "unprognostic (2.76e-2)" "unprognostic (1.30e-1)" "unprognostic (2.62e-2)" "unprognostic (7.53e-2)" 0.0 0.0 0.9 0.0 0.9 0.0 0.1 0.8 1.1 0.0 1.2 75.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.8 0.5 0.0 0.0 0.0 1.1 1.0 0.0 0.0 0.0 0.2 0.0 0.9 0.1 128.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.4 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.8 1.1 0.8 0.8 1.1 1.0 0.9 0.9 0.8 0.9 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.2 0.0 0.0 0.2 0.3 0.0 0.0 8836.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 22.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 11.4 0.0 INSL6 RIF1 ENSG00000120210 "Insulin like 6" Q9Y581 9 5123880-5185647 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "retina: 6.8;testis: 14.9" "Cell type enhanced" "Detected in some" "Early spermatids: 134.0;Excitatory neurons: 22.0;Inhibitory neurons: 26.2;Late spermatids: 17.9;Microglial cells: 21.5;Spermatocytes: 35.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 1.1;Karpas-707: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021364 Enhanced "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA021364: AB_1851807" "unprognostic (3.85e-4)" "unprognostic (7.41e-4)" "unprognostic (1.28e-1)" "unprognostic (1.94e-1)" "unprognostic (2.22e-1)" "unprognostic (6.92e-2)" "unprognostic (2.31e-2)" "unprognostic (3.82e-2)" "unprognostic (2.30e-1)" "unprognostic (2.52e-3)" 0.1 0.3 0.5 0.6 0.7 1.5 0.0 1.1 1.2 0.0 0.1 0.2 0.3 0.4 0.0 0.4 0.1 0.5 0.5 0.4 0.9 0.1 0.1 0.2 1.0 0.6 0.2 0.4 0.0 0.0 0.0 0.8 0.6 0.2 0.0 6.8 0.2 0.0 0.3 1.0 0.2 0.0 0.1 1.1 0.6 14.9 0.5 0.1 0.2 0.0 0.1 0.1 0.0 1.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 1.1 0.3 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.3 1.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.2 0.2 0.1 0.2 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.7 1.1 1.2 0.4 0.9 0.6 0.2 0.6 0.1 0.5 1.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 134.0 0.1 0.0 0.1 0.0 0.0 22.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 26.2 0.0 0.0 0.0 0.0 17.9 1.2 0.0 0.0 21.5 0.0 0.0 0.0 9.5 8.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 35.7 10.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 INTS11 "CPSF3L, CPSF73L, FLJ20542, INT11, RC-68" ENSG00000127054 "Integrator complex subunit 11" Q5TA45 1 1311585-1324687 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.3;Ductal cells: 56.4;Extravillous trophoblasts: 63.9;Syncytiotrophoblasts: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028379, HPA029025" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol Nucleoplasm "HPA028379: AB_10599598, HPA029025: AB_10600425" "unprognostic (7.54e-2)" "unprognostic (2.14e-3)" "unprognostic (2.33e-2)" "unprognostic (2.56e-1)" "unprognostic (2.99e-2)" "unprognostic (9.34e-2)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.97e-1)" "unprognostic (1.71e-1)" "unprognostic (2.75e-2)" "unprognostic (1.33e-2)" "unprognostic (3.08e-2)" "unprognostic (1.72e-2)" "unprognostic (1.27e-1)" "unprognostic (2.76e-3)" "unprognostic (5.14e-2)" "unprognostic (5.62e-3)" 39.7 40.8 26.0 24.0 28.6 29.0 39.0 37.2 40.1 64.7 27.7 70.6 32.8 66.6 26.4 43.9 61.1 24.1 54.9 27.2 28.4 40.4 45.7 35.6 31.8 30.3 27.2 63.6 53.6 28.9 40.0 28.2 30.6 52.9 20.8 13.0 38.3 27.6 90.3 47.2 44.9 26.7 24.5 45.4 52.4 76.0 28.0 29.6 40.7 44.2 25.1 67.5 50.6 33.6 58.4 56.2 31.5 62.1 52.4 41.7 34.1 31.2 49.9 67.6 50.1 53.2 71.0 63.2 43.6 60.7 40.6 41.4 46.3 67.7 29.9 60.3 60.5 49.8 79.7 70.2 80.2 39.1 52.5 72.1 35.9 61.7 91.7 38.2 71.7 59.7 59.5 56.3 34.2 50.8 77.6 52.1 39.1 53.6 60.1 61.0 30.8 93.1 47.6 31.3 45.0 42.1 31.9 83.8 91.7 23.4 45.5 57.0 54.5 43.6 39.6 50.8 40.0 87.3 101.8 85.1 60.4 68.7 22.0 66.5 69.6 48.0 65.2 82.1 68.9 50.3 56.4 59.8 81.2 44.0 52.2 50.2 33.2 64.8 101.7 52.9 78.7 81.0 26.0 28.6 37.2 40.1 27.2 28.4 30.3 27.2 30.6 24.5 28.0 33.6 36.4 38.5 33.7 0.0 9.5 0.0 0.0 0.0 0.0 0.0 32.6 33.9 0.0 0.0 13.0 18.4 0.0 77.3 24.1 0.0 31.3 56.4 0.0 27.1 27.2 14.0 0.0 0.0 0.0 53.9 63.9 18.7 0.0 23.2 10.1 40.4 0.0 0.0 42.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 36.2 0.0 0.0 0.0 0.0 54.8 0.0 0.0 6.8 0.0 0.0 34.4 14.6 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 77.0 12.7 49.8 0.0 0.0 INTS14 "C15orf44, DKFZP564O1664, VWA9" ENSG00000138614 "Integrator complex subunit 14" Q96SY0 15 65578753-65611289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.5;Extravillous trophoblasts: 30.5;Syncytiotrophoblasts: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040255, HPA040651" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Mitochondria" No No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear bodies, Mitochondria" "Nuclear membrane" "HPA040255: AB_10805710, HPA040651: AB_10796559" "unprognostic (2.92e-1)" "unprognostic (3.01e-1)" "unprognostic (2.78e-1)" "unprognostic (2.41e-1)" "unprognostic (4.06e-1)" "unprognostic (2.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.63e-1)" "unprognostic (5.80e-2)" "unprognostic (5.60e-2)" "unprognostic (2.57e-2)" "unprognostic (2.67e-2)" "unprognostic (1.03e-3)" "unprognostic (1.92e-2)" "unprognostic (1.23e-1)" "unprognostic (5.75e-2)" "unprognostic (1.30e-1)" 12.5 15.8 13.2 14.2 15.8 18.0 22.3 14.7 16.6 20.9 18.2 21.8 14.1 18.1 27.4 16.1 24.2 19.6 13.4 13.5 14.8 21.3 21.1 15.6 22.7 14.5 14.9 18.4 17.7 22.9 16.3 19.2 14.6 19.1 23.6 13.1 16.2 19.8 9.9 18.0 17.2 18.8 14.8 18.9 18.1 18.9 15.8 25.4 23.2 13.6 24.3 23.6 13.6 17.7 26.4 46.7 46.1 36.8 25.2 31.4 29.5 28.4 36.5 46.4 42.5 42.2 61.2 42.9 38.9 35.6 38.5 52.0 99.4 47.6 40.5 37.8 60.2 37.5 32.2 46.4 50.0 38.7 46.2 30.6 46.9 35.1 53.7 34.1 50.8 64.8 52.2 24.3 33.4 41.7 44.3 41.2 33.8 66.2 25.6 37.5 38.8 49.0 36.7 48.6 33.1 26.3 34.2 34.5 49.5 39.2 32.3 44.0 25.2 31.8 33.2 28.8 45.6 23.9 48.4 58.1 32.1 70.0 38.1 25.7 11.0 6.2 19.8 12.7 22.3 19.3 20.3 22.6 19.8 14.8 21.1 19.2 1.2 23.8 9.5 17.9 30.8 16.6 13.2 15.8 14.7 16.6 13.5 14.8 14.5 14.9 14.6 14.8 15.8 17.7 12.2 22.4 10.9 0.0 3.8 0.0 0.0 0.0 0.0 0.0 13.0 11.0 0.0 0.0 5.6 12.9 0.0 40.5 7.7 0.0 21.5 18.2 0.0 12.8 11.8 6.8 0.0 0.0 0.0 15.4 30.5 6.7 0.0 12.6 7.6 22.5 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 9.3 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.5 0.0 0.0 15.1 10.9 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 49.8 4.8 24.0 0.0 0.0 INTS3 "C1orf60, FLJ21919, INT3, SOSS-A" ENSG00000143624 "Integrator complex subunit 3" Q68E01 1 153728050-153774808 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074391 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoli Nucleoplasm "HPA074391: AB_2686685" "unprognostic (2.36e-1)" "unprognostic (1.94e-2)" "unprognostic (8.75e-3)" "unprognostic (6.97e-3)" "unprognostic (3.26e-1)" "unprognostic (4.48e-2)" "unprognostic (1.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.75e-1)" "unprognostic (2.45e-1)" "prognostic favorable (5.42e-4)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.34e-6)" "unprognostic (1.21e-1)" "unprognostic (1.85e-1)" "unprognostic (1.18e-3)" "unprognostic (8.29e-2)" 14.3 18.7 1.7 10.8 2.0 2.9 14.7 0.5 3.2 16.8 0.9 16.1 4.2 18.3 13.4 12.1 20.7 9.7 13.0 2.2 2.1 15.9 11.8 14.9 8.6 2.7 0.9 23.3 13.0 8.2 17.8 9.6 1.3 11.9 6.5 3.6 12.1 11.3 14.9 12.2 12.9 9.4 0.0 13.2 16.7 12.8 4.4 6.7 15.3 8.3 7.7 13.6 14.4 1.5 26.2 15.8 14.0 19.2 21.3 17.4 19.1 18.2 8.7 21.7 17.4 8.5 24.5 21.3 37.8 24.2 11.8 27.0 28.0 18.7 10.2 24.6 23.0 15.4 37.7 3.8 13.8 18.8 20.5 12.3 7.5 9.5 11.7 17.5 14.4 13.8 19.2 14.6 9.0 8.5 18.6 10.0 23.6 25.5 26.8 24.5 6.4 13.1 8.1 24.7 11.8 15.5 18.9 39.7 11.4 18.4 13.3 25.3 6.1 22.7 6.7 18.1 18.1 17.1 13.7 19.5 24.9 8.9 11.3 0.0 0.8 0.9 0.9 0.5 0.8 0.3 0.3 0.5 1.2 0.3 0.2 0.5 0.8 0.7 2.9 0.3 0.5 0.2 1.7 2.0 0.5 3.2 2.2 2.1 2.7 0.9 1.3 0.0 4.4 1.5 29.1 22.4 22.8 59.7 11.9 10.5 9.5 10.4 15.9 23.7 20.2 22.4 4.6 10.0 11.7 31.3 20.9 13.9 11.6 9.2 0.0 11.9 13.1 39.3 29.4 21.5 12.1 10.9 30.8 8.4 13.4 16.3 23.9 38.8 5.7 32.9 26.7 13.9 12.2 21.9 26.1 16.5 8.2 9.1 22.0 7.6 9.6 14.6 7.2 30.0 17.6 15.4 14.4 27.2 29.7 9.9 14.9 12.0 11.6 10.6 9.8 13.3 25.9 22.4 26.3 11.2 16.5 10.2 12.2 13.9 10.2 10.3 10.0 20.2 14.0 12.2 IPO11 RanBP11 ENSG00000086200 "Importin 11" Q9UI26 5 62403972-62628582 "Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 68.4;Hepatic stellate cells: 65.0;Inhibitory neurons: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 22.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065346, HPA067097" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA065346: , HPA067097: AB_2685776" "unprognostic (9.29e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (3.35e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (4.28e-5)" "unprognostic (4.26e-2)" "unprognostic (6.45e-2)" "unprognostic (1.26e-3)" "unprognostic (9.63e-2)" "unprognostic (5.09e-2)" "unprognostic (8.38e-3)" "unprognostic (1.62e-1)" "unprognostic (1.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.24e-2)" 16.0 9.1 13.4 9.7 13.7 6.6 14.4 13.6 14.6 10.6 16.3 9.2 6.9 9.4 8.5 12.0 10.2 10.7 14.7 14.7 13.7 11.9 11.4 7.7 10.4 14.1 13.7 9.4 8.6 13.4 6.0 16.5 13.6 9.0 8.6 6.3 8.5 8.4 12.6 8.8 7.9 11.0 14.4 13.4 8.5 21.4 13.9 10.0 14.0 14.4 10.1 13.4 9.9 15.7 27.1 25.4 22.3 34.6 17.0 23.4 30.9 28.4 20.5 29.1 31.9 27.5 20.2 45.3 22.2 28.9 35.5 21.4 47.3 32.0 45.6 17.5 24.6 21.6 24.5 24.4 12.8 23.7 11.6 16.7 17.7 34.3 35.7 13.7 113.8 22.4 41.5 14.5 27.9 26.0 26.1 32.2 28.0 15.4 14.5 31.6 33.7 41.6 17.7 26.4 24.1 13.9 24.8 19.3 21.0 21.9 24.9 17.0 51.8 17.4 19.3 19.8 26.4 11.3 20.0 31.3 21.2 33.4 21.3 16.5 2.4 2.2 3.8 3.8 4.5 3.3 3.9 3.9 4.0 4.8 5.5 4.0 2.5 22.7 7.0 2.4 2.8 3.6 13.4 13.7 13.6 14.6 14.7 13.7 14.1 13.7 13.6 14.4 13.9 15.7 39.6 9.6 3.7 35.9 11.8 8.5 4.2 3.3 13.6 4.2 6.2 4.8 13.2 5.7 4.5 7.3 2.1 7.6 7.9 2.7 3.9 4.2 42.2 8.4 7.0 40.0 3.0 21.7 68.4 5.5 6.7 7.6 6.1 5.6 13.3 9.6 65.0 6.2 5.2 5.0 55.0 4.4 2.0 6.5 6.4 25.3 5.6 7.4 3.6 20.6 2.6 3.9 10.3 28.1 48.3 3.3 1.7 4.1 10.7 5.2 2.6 3.6 25.6 4.9 6.6 9.7 8.7 14.6 16.2 10.9 8.8 5.1 8.8 4.6 5.7 4.8 IPO8 "IMP8, RANBP8" ENSG00000133704 "Importin 8" O15397 12 30628988-30695869 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018439, HPA023765" Uncertain Approved Nucleoplasm NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 5: NTERA-2 - Transcription" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA018439: AB_1851771, HPA023765: AB_1851773" "unprognostic (1.63e-2)" "unprognostic (1.40e-1)" "unprognostic (1.73e-1)" "unprognostic (5.14e-2)" "unprognostic (2.15e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.35e-4)" "unprognostic (2.66e-2)" "unprognostic (5.42e-2)" "unprognostic (1.20e-1)" "unprognostic (2.97e-1)" "unprognostic (1.38e-1)" "prognostic favorable (8.62e-5)" "unprognostic (9.75e-2)" "unprognostic (2.95e-1)" "unprognostic (3.14e-3)" "unprognostic (2.24e-1)" 20.1 21.6 17.8 23.0 21.8 16.5 22.2 25.3 19.9 22.1 26.1 29.4 26.6 23.9 17.1 24.2 17.2 21.4 16.7 19.1 21.4 32.2 34.6 23.1 28.1 22.0 19.8 26.6 27.8 51.9 15.5 22.5 20.9 21.8 32.2 22.8 19.8 25.4 18.5 24.3 23.7 26.8 18.1 25.2 24.1 24.5 20.9 29.3 31.7 21.7 27.5 23.9 15.5 22.8 41.2 46.8 44.3 32.9 40.9 46.8 62.3 44.4 42.5 34.9 40.6 32.9 41.8 52.9 38.1 54.8 37.0 25.8 49.7 48.4 50.5 62.0 35.1 43.1 56.0 29.8 26.8 63.3 32.8 37.8 29.8 55.5 47.1 62.5 58.5 36.4 39.2 38.7 49.9 21.0 47.6 39.3 86.7 56.5 18.1 38.5 93.1 42.7 43.6 55.5 27.3 33.7 46.6 33.7 25.0 78.6 53.8 22.7 52.4 33.2 29.0 72.3 39.3 38.0 54.9 78.4 40.6 37.4 58.7 3.4 1.9 2.4 1.9 2.5 2.8 2.4 2.1 2.0 1.4 3.2 2.2 3.0 2.5 2.6 2.6 1.4 2.8 1.3 17.8 21.8 25.3 19.9 19.1 21.4 22.0 19.8 20.9 18.1 20.9 22.8 18.4 9.6 21.0 22.2 17.3 9.6 6.7 6.3 12.5 13.4 12.2 7.4 20.3 8.6 16.6 11.0 12.5 11.8 13.5 17.2 3.9 10.1 51.5 14.3 17.5 17.5 6.7 14.5 38.8 14.0 6.8 13.4 16.8 14.2 12.0 25.0 21.0 25.1 16.1 8.4 35.0 13.8 8.2 24.8 10.8 11.9 8.7 17.4 8.8 30.9 16.7 12.7 18.6 59.8 35.7 14.1 8.1 13.2 17.5 7.6 15.0 15.7 9.9 14.3 13.1 17.0 14.8 17.4 5.2 23.4 9.2 17.9 13.6 11.1 14.8 9.0 IPO9 "FLJ10402, Imp9" ENSG00000198700 "Importin 9" Q96P70 1 201829149-201884291 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059540 Approved Vesicles,Cytosol "Intracellular and membrane" NA NA 70000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" Cytosol Vesicles "HPA059540: " "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (7.44e-3)" "unprognostic (2.02e-2)" "unprognostic (1.13e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (4.11e-5)" "unprognostic (8.92e-3)" "unprognostic (2.23e-3)" "unprognostic (2.52e-1)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.86e-4)" "unprognostic (5.05e-2)" "unprognostic (2.57e-1)" "unprognostic (3.13e-2)" "prognostic unfavorable (5.78e-4)" 17.0 18.2 17.8 12.0 17.8 10.1 16.5 18.0 22.5 18.9 16.4 15.9 9.2 19.2 18.2 15.7 15.2 9.2 15.9 18.8 17.6 17.4 26.9 17.9 13.7 17.3 16.7 17.2 17.9 14.8 20.7 14.5 16.8 17.5 13.9 23.7 12.3 10.8 14.0 17.7 15.1 16.7 15.0 19.6 14.3 14.4 17.8 16.2 19.3 10.7 16.7 16.6 15.0 17.1 45.4 46.9 63.0 51.4 35.7 24.1 47.1 34.2 34.3 55.6 53.8 75.6 38.4 26.8 18.9 32.9 48.8 41.0 43.0 47.2 47.9 24.5 38.1 20.0 75.2 57.2 27.2 26.2 31.4 26.7 21.3 60.2 48.5 37.1 56.7 36.0 40.5 24.6 40.4 45.1 30.5 34.2 63.4 40.6 15.2 32.2 65.8 26.6 30.7 71.0 53.3 60.5 37.5 58.7 30.8 96.6 43.1 32.8 31.1 52.1 46.6 29.5 63.5 18.1 12.0 31.5 25.9 30.5 39.8 10.1 10.1 8.7 9.9 13.2 8.6 9.5 9.5 10.9 12.6 8.5 7.6 8.3 2.3 10.2 13.8 6.6 9.5 7.8 17.8 17.8 18.0 22.5 18.8 17.6 17.3 16.7 16.8 15.0 17.8 17.1 25.7 22.4 45.6 48.0 22.1 15.8 14.9 14.3 13.6 57.9 14.5 14.7 23.6 10.0 20.4 7.3 60.5 27.8 17.6 7.5 1.9 16.9 8.0 9.2 28.9 27.3 11.3 28.6 60.1 18.7 20.8 25.4 16.3 11.2 11.4 32.6 23.2 18.1 19.5 75.7 60.7 16.3 10.2 17.6 21.5 8.8 20.2 13.3 14.2 36.5 21.6 38.1 26.8 46.8 50.6 17.6 10.6 28.2 18.2 16.4 8.9 9.0 10.5 56.5 39.5 35.4 26.1 42.0 37.3 16.4 14.2 22.6 17.0 26.0 17.0 12.5 IQSEC2 "BRAG1, IQ-ArfGEF, KIAA0522, MRX1, MRX18, MRX78" ENSG00000124313 "IQ motif and Sec7 domain ArfGEF 2" Q5JU85 X 53225828-53321350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 54.0;Late spermatids: 41.6;Proximal enterocytes: 42.1;Proximal tubular cells: 52.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 10.4;plasmacytoid DC: 10.6" "Group enriched" "Detected in many" 16 "dendritic cells: 10.6;monocytes: 10.4" "Cell line enhanced" "Detected in many" "A549: 47.3;GAMG: 58.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003973, HPA076533" Approved "Vesicles,Lipid droplets" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 47: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Lipid droplets" "HPA003973: AB_2280343, HPA076533: " "unprognostic (1.85e-1)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (1.32e-1)" "unprognostic (4.66e-3)" "unprognostic (6.02e-2)" "unprognostic (2.80e-1)" "unprognostic (3.78e-2)" "unprognostic (2.82e-1)" "unprognostic (9.05e-2)" "unprognostic (1.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.56e-2)" "unprognostic (1.75e-1)" "unprognostic (4.30e-2)" "prognostic favorable (2.38e-4)" 10.8 18.8 18.3 5.8 22.4 2.4 9.9 9.8 32.3 9.7 0.0 14.9 12.5 12.0 4.4 9.5 10.7 6.1 11.2 35.8 0.0 19.4 1.9 8.7 2.8 2.4 0.1 7.6 9.0 14.1 10.9 3.8 2.8 12.0 7.1 3.0 14.9 8.8 58.7 8.9 14.2 7.3 0.3 5.3 10.4 9.9 0.2 3.4 9.7 34.0 3.4 12.1 9.8 14.2 4.8 47.3 1.8 4.4 6.5 13.1 5.3 7.7 13.4 6.2 10.9 1.2 18.2 0.3 12.4 18.3 58.5 6.4 1.7 7.7 4.4 4.8 8.3 5.4 20.8 1.3 14.2 0.2 2.8 9.8 11.8 16.1 9.0 14.4 8.5 0.1 17.3 5.3 12.4 11.2 0.0 1.0 14.6 14.2 21.0 3.5 3.7 6.0 9.0 10.1 1.9 1.8 18.0 11.0 7.5 8.3 15.7 2.3 9.5 5.6 10.6 3.1 3.5 1.5 0.2 0.2 34.6 3.5 3.1 0.1 10.4 0.5 0.0 3.7 0.1 0.2 0.0 0.0 5.4 0.1 0.1 0.0 0.6 0.0 2.0 10.6 0.0 2.3 18.3 22.4 9.8 32.3 35.8 0.0 2.4 0.1 2.8 0.3 0.2 14.2 8.4 6.4 5.9 15.0 1.4 4.0 6.7 11.5 7.4 1.5 12.2 9.5 4.0 12.8 9.3 14.7 0.0 8.0 2.0 21.1 21.5 5.2 18.0 5.4 3.5 6.2 3.6 0.8 54.0 7.1 6.5 6.6 8.2 4.7 3.8 9.1 6.4 0.9 14.7 0.0 25.7 9.7 8.2 12.0 5.0 41.6 1.5 14.1 10.6 17.8 11.9 5.0 0.0 9.5 2.5 5.5 12.6 2.2 1.0 7.0 42.1 52.4 7.6 0.1 0.0 2.7 8.4 0.8 1.5 9.3 3.8 4.5 1.5 2.5 10.7 14.6 IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66189195-66254622 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.1" "Cell type enhanced" "Detected in many" "Adipocytes: 83.3;Kupffer cells: 123.0;Macrophages: 126.3;Microglial cells: 114.3;monocytes: 96.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 12.7;classical monocyte: 23.4;intermediate monocyte: 24.2;myeloid DC: 11.5;neutrophil: 12.9;non-classical monocyte: 42.0" "Group enriched" "Detected in many" 12 "dendritic cells: 11.5;granulocytes: 12.9;monocytes: 42.0" "Cell line enhanced" "Detected in many" "ASC diff: 25.9;ASC TERT1: 21.1;HEL: 22.9;HL-60: 30.8;NB-4: 25.1;THP-1: 37.3;U-937: 26.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA043097: AB_10795612" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-3)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (7.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.58e-2)" "unprognostic (4.64e-2)" "unprognostic (3.41e-2)" "unprognostic (3.23e-2)" 18.7 3.8 3.7 12.4 4.1 78.1 11.6 4.1 7.5 9.3 5.4 4.6 1.3 4.0 3.0 3.8 8.0 6.9 7.9 3.2 4.7 3.5 2.8 19.0 4.1 5.6 5.7 3.2 2.5 0.9 8.9 6.8 6.5 5.3 2.8 0.4 6.2 5.6 2.6 3.4 5.6 5.4 5.0 27.5 6.9 1.8 5.6 2.7 5.0 4.6 3.9 8.4 6.6 5.1 0.0 0.0 0.4 0.0 25.9 21.1 0.0 2.9 0.0 1.5 2.3 0.0 2.2 0.0 1.4 5.3 0.0 0.0 3.2 0.0 1.3 0.0 0.0 22.9 1.4 0.0 13.4 30.8 4.0 13.5 0.1 1.2 0.0 0.0 7.6 0.0 0.0 0.0 1.0 0.0 0.0 25.1 1.3 0.0 0.0 0.0 6.4 0.0 0.1 3.3 0.1 0.0 11.6 0.0 1.2 0.1 0.1 37.3 8.2 0.0 0.0 0.0 0.0 0.9 0.2 2.2 0.0 26.8 0.0 12.7 23.4 4.3 0.0 24.2 0.0 0.1 0.0 0.0 11.5 0.7 0.0 0.0 12.9 1.8 42.0 0.1 0.6 7.3 3.7 4.1 4.1 7.5 3.2 4.7 5.6 5.7 6.5 5.0 5.6 5.1 83.3 9.6 19.4 1.3 2.3 1.5 4.8 27.5 6.2 0.3 2.5 1.8 2.8 0.0 46.9 3.7 0.0 0.2 14.8 0.5 0.0 0.6 6.4 0.5 7.5 38.5 0.0 9.7 0.4 1.2 0.4 22.3 18.3 0.5 27.3 0.5 36.4 1.2 9.4 0.0 5.6 1.1 36.7 123.0 12.1 5.3 7.2 126.3 5.4 114.3 96.9 0.2 3.1 2.0 0.6 4.9 0.1 11.3 9.1 1.6 0.0 0.2 35.1 0.1 0.0 18.1 10.2 0.8 1.8 1.2 1.3 0.3 3.5 12.5 0.7 2.5 IRS4 "IRS-4, PY160" ENSG00000133124 "Insulin receptor substrate 4" O14654 X 108719946-108736563 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.7;choroid plexus: 8.0;pituitary gland: 5.3" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 2.9;Oligodendrocytes: 1.1" "Cancer enhanced" "Detected in some" "breast cancer: 0.8" "Region enhanced" "Detected in many" "hypothalamus: 14.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 9.4;NTERA-2: 1.3;RT4: 3.1;WM-115: 2.2" "Group enriched" "Detected in many" 5 "basal ganglia: 11.7;hypothalamus: 45.0" "Group enriched" "Detected in many" 5 "basal ganglia: 14.5;hypothalamus: 36.7" HPA017372 Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA017372: AB_2669600" "unprognostic (3.74e-3)" "unprognostic (3.27e-2)" "unprognostic (1.32e-2)" "unprognostic (2.52e-1)" "unprognostic (1.89e-1)" "unprognostic (2.12e-1)" "unprognostic (1.65e-1)" "unprognostic (1.05e-2)" "unprognostic (1.77e-1)" "unprognostic (9.28e-4)" "unprognostic (8.71e-2)" 0.0 0.0 4.1 0.0 1.3 0.0 0.0 0.0 0.5 1.0 8.0 0.0 0.0 1.4 0.5 0.0 0.2 0.0 0.0 1.3 14.7 0.0 0.0 0.0 0.0 2.0 2.6 4.6 0.0 0.0 5.3 0.0 3.3 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.5 0.9 0.0 0.2 0.0 10.6 3.8 1.8 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 1.3 0.0 0.5 1.3 14.7 2.0 2.6 3.3 0.9 10.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ISLR2 KIAA1465 ENSG00000167178 "Immunoglobulin superfamily containing leucine rich repeat 2" Q6UXK2 15 74100311-74138540 "Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 32.1;testis: 13.6" "Group enriched" "Detected in some" 5 "Early spermatids: 52.1;Late spermatids: 64.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 32.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "SCLC-21H: 57.9;SH-SY5Y: 86.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA012930, HPA067333" Uncertain NA NA 110000 "Cluster 78: Testis - Spermatogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "HPA012930: AB_2668772, HPA067333: AB_2685824" "unprognostic (1.31e-2)" "unprognostic (3.27e-3)" "unprognostic (1.44e-2)" "unprognostic (8.65e-3)" "unprognostic (1.53e-3)" "unprognostic (7.73e-2)" "unprognostic (6.64e-2)" "unprognostic (1.46e-2)" "unprognostic (9.19e-3)" "unprognostic (1.72e-1)" "unprognostic (2.94e-2)" "unprognostic (2.46e-1)" "unprognostic (2.44e-4)" "unprognostic (1.31e-2)" "unprognostic (1.75e-1)" "unprognostic (1.05e-1)" "unprognostic (2.64e-2)" 1.7 1.3 9.9 0.6 32.1 0.1 1.6 0.0 16.0 2.7 0.0 1.0 0.6 2.7 0.2 0.7 1.2 1.0 4.6 11.0 3.9 0.3 0.1 0.7 2.1 0.0 0.0 0.2 0.8 0.6 0.6 0.2 0.0 0.4 0.4 1.2 0.7 0.5 2.2 0.6 1.2 1.1 0.0 0.9 0.6 13.6 6.6 0.2 0.4 3.1 0.2 0.4 0.3 8.5 0.0 0.3 5.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 57.9 86.2 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.2 0.1 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 9.9 32.1 0.0 16.0 11.0 3.9 0.0 0.0 0.0 0.0 6.6 8.5 9.8 0.0 0.6 0.7 0.0 0.1 0.0 0.1 0.6 1.9 0.2 0.3 6.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 52.1 0.3 3.8 3.3 0.0 0.0 5.4 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 64.1 0.3 0.2 0.0 6.5 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 1.4 0.0 0.3 0.4 1.9 0.6 0.1 0.0 0.0 0.1 0.1 0.0 0.0 ISM1 "bA149I18.1, C20orf82" ENSG00000101230 "Isthmin 1" B1AKI9 20 13221274-13300651 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 44.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 19.2;Fibroblasts: 18.4;Microglial cells: 8.4;Proximal tubular cells: 5.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Group enriched" "Detected in some" 5 "ASC diff: 48.9;Hep G2: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA 17000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (7.13e-2)" "unprognostic (3.55e-1)" "unprognostic (4.43e-3)" "unprognostic (5.27e-3)" "unprognostic (1.84e-2)" "unprognostic (5.56e-2)" "unprognostic (2.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (2.06e-1)" "unprognostic (4.48e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (9.32e-6)" "unprognostic (2.58e-2)" "unprognostic (2.10e-1)" "unprognostic (6.83e-2)" "unprognostic (1.81e-2)" 13.2 2.6 1.2 0.3 1.2 0.0 16.6 0.9 1.5 3.3 0.5 2.0 0.4 3.1 0.3 6.6 4.4 4.8 2.9 1.1 3.5 2.1 6.3 4.4 0.3 1.4 1.6 0.5 3.8 0.4 2.1 14.4 1.5 1.6 0.2 0.1 15.2 0.7 1.5 17.0 2.6 1.9 1.3 8.1 3.3 0.1 3.6 4.9 44.4 2.0 0.7 1.3 5.6 0.8 0.0 0.5 0.2 0.7 48.9 6.8 0.3 0.4 4.2 0.0 0.0 2.9 0.4 0.0 0.2 0.0 0.4 0.2 0.0 0.1 0.0 0.0 4.1 0.0 0.0 20.0 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.4 0.0 0.5 0.5 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.1 4.2 0.0 0.0 1.4 0.2 0.9 0.0 0.0 0.0 2.9 0.4 0.1 0.3 0.0 4.7 0.9 0.0 2.3 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 1.2 0.9 1.5 1.1 3.5 1.4 1.6 1.5 1.3 3.6 0.8 1.9 0.0 0.5 0.0 0.0 4.6 0.4 0.4 0.6 0.8 0.5 19.2 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.1 0.2 2.0 2.0 0.0 0.0 0.6 0.0 0.3 18.4 0.0 0.2 0.0 3.4 0.0 2.3 0.5 0.0 4.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 1.8 8.4 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.4 0.1 0.5 0.0 5.2 0.0 0.0 0.0 0.4 1.4 0.0 0.3 0.3 2.8 0.7 0.9 0.0 0.0 0.1 ISM2 "FLJ32147, TAIL1, THSD3" ENSG00000100593 "Isthmin 2" Q6H9L7 14 77474394-77498816 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "placenta: 213.4" "Group enriched" "Detected in some" 10 "Cytotrophoblasts: 291.0;Extravillous trophoblasts: 617.2;Syncytiotrophoblasts: 177.5" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "BEWO: 386.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039314, HPA039742" Supported Supported Nucleoplasm "Secreted in female reproductive system" NA NA 1100000 "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA039314: AB_10673239, HPA039742: AB_10673427" "unprognostic (5.69e-2)" "unprognostic (9.17e-3)" "unprognostic (2.58e-2)" "unprognostic (1.41e-3)" "unprognostic (3.73e-2)" "unprognostic (2.34e-1)" "unprognostic (2.16e-2)" "unprognostic (3.09e-3)" "unprognostic (2.11e-1)" "unprognostic (4.13e-1)" "unprognostic (8.10e-2)" "unprognostic (1.42e-2)" "unprognostic (9.36e-2)" "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (3.95e-1)" 0.6 0.0 0.3 0.1 1.2 0.0 0.0 0.0 0.7 0.8 0.8 0.2 0.1 1.2 3.7 0.2 0.4 0.1 0.1 0.2 0.6 0.7 0.0 0.0 0.0 0.1 0.3 0.1 0.6 0.4 0.5 213.4 0.2 1.8 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.6 0.8 0.0 0.2 0.0 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 386.3 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 25.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.3 0.5 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.7 0.2 0.6 0.1 0.3 0.2 0.1 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 291.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.4 0.0 617.2 2.1 0.0 0.0 0.0 0.1 0.0 0.0 33.4 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.7 1.7 0.0 0.0 177.5 0.0 0.0 0.0 0.0 ISOC1 CGI-111 ENSG00000066583 "Isochorismatase domain containing 1" Q96CN7 5 129094749-129114028 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SH-SY5Y: 156.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070307 Approved "Endoplasmic reticulum,Vesicles" NA NA 1900000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum, Vesicles" "HPA070307: AB_2686249" "unprognostic (1.67e-1)" "unprognostic (4.46e-2)" "unprognostic (1.29e-1)" "unprognostic (6.42e-3)" "unprognostic (3.87e-2)" "unprognostic (1.91e-1)" "unprognostic (6.32e-2)" "unprognostic (1.90e-1)" "unprognostic (2.47e-1)" "unprognostic (4.19e-2)" "unprognostic (2.00e-2)" "unprognostic (4.18e-1)" "unprognostic (7.09e-3)" "unprognostic (2.49e-1)" "unprognostic (2.65e-1)" "unprognostic (1.65e-2)" "unprognostic (1.32e-2)" 27.8 28.0 11.9 12.8 12.2 12.6 25.5 11.9 13.7 57.2 11.4 19.6 32.1 102.7 21.0 22.1 27.2 15.6 65.7 11.1 16.0 33.6 100.2 14.0 14.6 15.9 16.4 17.1 19.9 15.7 20.5 15.3 13.8 19.7 21.7 14.8 28.4 8.9 17.1 23.5 28.3 64.9 13.8 10.0 20.4 11.1 15.2 18.9 13.3 16.4 16.8 21.3 19.2 15.2 27.7 21.4 21.7 33.5 35.0 18.5 95.7 11.7 10.0 13.1 23.1 75.5 38.2 19.6 28.3 6.9 40.0 14.7 46.5 35.2 24.2 107.5 52.8 39.0 20.9 55.7 24.7 15.6 13.6 12.2 10.5 20.5 17.7 9.4 31.6 30.6 43.0 33.2 11.6 110.2 29.2 25.3 33.5 26.4 57.8 41.5 63.2 19.3 32.9 55.4 36.6 156.9 33.7 42.3 21.6 19.7 34.9 13.0 13.4 14.8 28.1 11.9 38.3 27.5 22.9 32.7 16.5 48.4 17.0 64.0 25.2 38.0 54.0 25.0 61.4 47.7 50.3 57.7 31.5 49.4 43.9 51.8 30.9 61.4 25.3 29.0 69.0 48.9 11.9 12.2 11.9 13.7 11.1 16.0 15.9 16.4 13.8 13.8 15.2 15.2 58.1 12.8 17.2 6.5 18.9 131.8 42.4 28.5 88.2 12.4 33.6 19.8 70.6 34.3 19.3 20.2 10.4 74.7 26.3 19.9 125.2 22.2 1.6 23.5 30.1 16.9 31.8 21.0 1.7 28.1 71.8 33.9 17.3 24.9 18.4 51.0 5.3 84.7 23.9 0.0 5.6 26.6 30.5 8.8 41.0 4.2 13.7 14.3 28.4 4.7 18.9 52.9 18.6 6.0 9.2 16.3 29.8 19.2 36.9 38.5 45.7 96.2 10.6 6.5 0.0 33.7 15.9 6.5 38.1 53.7 84.1 50.9 26.4 79.3 32.8 37.8 ITGA4 CD49D ENSG00000115232 "Integrin subunit alpha 4" P13612 2 181457202-181538940 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 47.1;lymphoid tissue: 74.1" "Group enriched" "Detected in many" 4 "B-cells: 86.3;dendritic cells: 151.5;Erythroid cells: 169.3;Macrophages: 72.0;monocytes: 73.8;NK-cells: 126.7;Plasma cells: 141.6;T-cells: 129.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 164.0;HEL: 308.1;JURKAT: 142.3;MOLT-4: 373.6" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 12.9" HPA074961 Approved "Plasma membrane" "Intracellular and membrane" NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074961: AB_2732273" "unprognostic (5.31e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-2)" "unprognostic (3.94e-2)" "unprognostic (3.76e-1)" "prognostic favorable (8.29e-4)" "unprognostic (1.27e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (2.26e-2)" "unprognostic (8.64e-3)" "unprognostic (2.49e-1)" "unprognostic (2.57e-2)" 3.3 2.3 1.2 31.5 0.5 47.1 3.8 4.1 1.5 12.7 3.0 8.7 8.7 3.3 1.4 2.3 1.5 9.8 1.5 4.1 1.3 2.7 5.7 12.7 37.2 1.4 1.6 1.4 1.5 0.9 0.4 14.7 2.9 3.5 10.3 8.6 2.9 2.5 0.6 1.2 11.7 5.2 0.9 45.5 10.4 0.8 2.4 74.1 2.0 0.9 26.1 9.5 1.4 1.3 0.3 1.3 4.6 0.1 38.9 55.0 0.0 42.3 46.7 19.5 42.0 0.0 0.0 32.4 0.2 164.0 17.4 23.4 14.0 0.7 22.3 0.0 3.4 308.1 1.1 0.0 4.0 123.4 6.8 39.2 0.0 1.2 0.0 20.5 2.3 142.3 0.1 45.5 12.7 0.0 373.6 117.9 3.7 0.0 0.2 78.1 20.3 5.1 0.0 0.0 8.2 2.6 0.1 0.4 1.4 1.6 0.0 82.9 23.2 6.5 4.1 0.7 8.5 90.9 77.5 18.6 3.7 59.5 90.3 29.5 55.0 137.4 42.0 131.3 32.1 37.3 46.9 52.4 66.0 33.0 26.5 33.1 7.1 32.2 139.6 17.5 13.4 65.2 1.2 0.5 4.1 1.5 4.1 1.3 1.4 1.6 2.9 0.9 2.4 1.3 2.8 0.0 6.7 0.0 86.3 0.3 0.2 1.2 0.0 2.3 1.1 1.4 1.2 2.8 1.8 0.0 6.2 0.1 151.5 0.1 0.0 0.0 0.0 4.4 6.5 1.4 0.0 169.3 9.4 0.0 0.3 6.3 7.1 6.4 18.9 0.3 1.8 0.2 5.9 0.0 0.5 0.1 0.0 24.5 4.4 0.0 0.6 72.0 0.0 7.5 73.8 0.2 126.7 15.6 0.3 0.0 0.4 0.0 141.6 0.3 0.0 0.2 0.8 6.4 0.0 0.7 8.3 0.7 1.2 0.3 0.6 0.4 129.9 0.4 0.2 0.2 ITGA9 "ALPHA-RLC, ITGA4L, RLC" ENSG00000144668 "Integrin subunit alpha 9" Q13797 3 37452115-37823507 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.0;Hepatic stellate cells: 54.3;Inhibitory neurons: 61.0;Leydig cells: 41.3;Microglial cells: 53.4;Oligodendrocyte precursor cells: 93.5;Peritubular cells: 74.9" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 23.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 10.1;HEL: 8.1;SH-SY5Y: 11.8;SuSa: 16.9;WM-115: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030609 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 500000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA030609: AB_10600815" "unprognostic (2.35e-2)" "unprognostic (3.36e-2)" "unprognostic (5.58e-2)" "unprognostic (3.94e-2)" "unprognostic (4.48e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (8.87e-3)" "unprognostic (3.23e-1)" "unprognostic (2.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.51e-1)" "unprognostic (1.78e-2)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-2)" "unprognostic (3.16e-2)" 8.8 15.5 1.9 4.5 1.8 8.5 5.9 0.0 6.2 21.8 3.6 9.6 6.3 10.6 4.0 15.5 5.4 9.4 20.1 7.8 0.7 4.0 14.8 8.9 4.1 0.9 1.3 5.0 1.8 2.6 1.7 9.8 0.4 12.5 6.8 0.7 4.2 10.8 2.8 3.0 9.1 15.8 0.7 22.6 7.5 6.9 5.0 1.8 20.7 9.8 2.4 6.5 4.5 1.2 0.2 0.0 4.3 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 10.1 0.0 3.2 1.4 0.0 0.1 0.2 3.8 0.0 0.0 0.1 0.6 8.1 0.1 0.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.4 0.3 0.0 0.2 0.5 11.8 0.1 0.5 0.7 16.9 0.0 3.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.2 6.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 0.0 6.2 7.8 0.7 0.9 1.3 0.4 0.7 5.0 1.2 20.8 0.0 14.7 16.0 0.1 2.5 1.1 0.1 1.2 1.2 1.1 2.9 12.9 2.8 3.1 1.8 0.0 0.2 0.0 0.0 0.0 0.1 1.5 1.4 4.9 21.6 0.0 3.0 82.0 0.0 0.5 7.5 0.0 0.9 6.3 36.2 54.3 1.3 2.8 0.0 61.0 0.1 0.0 31.9 2.2 4.2 41.3 5.7 3.6 53.4 0.1 0.6 0.0 93.5 6.2 0.0 0.0 74.9 0.4 0.2 0.0 0.1 0.0 0.0 0.0 3.2 3.3 0.6 0.9 0.0 1.7 0.3 1.8 25.9 0.4 0.3 ITGAX CD11C ENSG00000140678 "Integrin subunit alpha X" P20702 16 31355134-31382999 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 48.1;brain: 33.7;lung: 58.1;lymphoid tissue: 67.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 51.1;granulocytes: 74.0;Hofbauer cells: 45.1;Kupffer cells: 51.5;Langerhans cells: 77.3;Macrophages: 141.7;Microglial cells: 56.2;NK-cells: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 87.5" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 6 "HMC-1: 106.1" "Not detected" "Not detected" "CAB004458, HPA004723, CAB072871" Enhanced NA NA 50000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "CAB004458: AB_626859, CAB072871: AB_2665723, HPA004723: AB_1846231" "unprognostic (9.75e-3)" "unprognostic (2.49e-2)" "unprognostic (1.75e-1)" "unprognostic (1.99e-2)" "unprognostic (1.89e-1)" "unprognostic (2.29e-2)" "unprognostic (1.27e-1)" "unprognostic (9.59e-2)" "unprognostic (8.06e-3)" "unprognostic (3.20e-1)" "unprognostic (7.75e-2)" "unprognostic (3.34e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (3.92e-2)" "unprognostic (3.04e-2)" "unprognostic (2.82e-1)" "unprognostic (2.95e-2)" 12.9 2.3 6.0 42.7 8.1 48.1 4.3 8.8 33.7 2.2 8.4 2.9 2.3 2.8 0.8 2.0 5.9 10.8 3.5 6.2 9.3 2.9 6.3 58.1 23.2 14.6 11.8 1.0 2.9 1.4 2.9 4.6 14.3 3.2 4.3 0.6 4.5 1.5 1.3 2.1 5.5 4.7 13.0 67.5 4.8 0.6 18.4 4.0 2.8 3.2 12.3 9.2 2.1 24.8 0.1 0.6 0.1 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.4 0.0 9.0 0.0 0.3 0.1 0.0 0.3 0.1 18.6 0.1 0.1 0.3 0.4 0.0 1.1 106.1 0.1 0.1 1.7 0.2 0.7 1.0 0.0 0.1 0.4 0.0 0.0 0.1 8.8 0.4 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.1 0.0 3.3 0.8 0.0 1.6 0.0 0.1 0.1 0.0 0.2 4.9 1.8 0.3 12.8 29.1 27.1 4.8 50.3 0.4 2.1 0.1 0.7 34.7 1.0 0.1 0.7 87.5 41.4 61.0 0.6 0.1 11.5 6.0 8.1 8.8 33.7 6.2 9.3 14.6 11.8 14.3 13.0 18.4 24.8 0.8 12.8 51.1 0.0 9.8 2.8 0.3 0.0 0.0 0.1 0.6 1.3 1.5 0.0 10.5 0.0 0.0 0.4 33.6 0.0 0.0 0.3 0.0 0.4 0.5 4.8 0.0 3.4 0.2 0.0 0.6 4.4 0.0 0.5 74.0 0.0 1.1 0.1 45.1 0.0 0.3 0.0 0.0 51.5 77.3 0.0 0.0 141.7 1.8 56.2 35.3 0.1 68.0 0.5 0.3 0.2 0.0 0.0 5.5 0.2 0.0 0.3 1.5 0.1 0.0 0.6 1.0 0.0 0.2 0.0 1.1 0.4 16.5 0.1 0.0 0.1 ITGB1 "CD29, FNRB, GPIIA, MDF2, MSK12" ENSG00000150093 "Integrin subunit beta 1" P05556 10 32887273-33005792 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1206.9;Pancreatic endocrine cells: 1393.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 2711.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003434, HPA059297, HPA069003" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Focal adhesion sites" NA NA 270000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Focal adhesion sites" "Endoplasmic reticulum" "CAB003434: AB_303570, HPA059297: AB_2732634, HPA069003: AB_2732125" "unprognostic (3.07e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.67e-2)" "unprognostic (4.36e-1)" "unprognostic (1.20e-2)" "unprognostic (3.87e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.22e-1)" "unprognostic (2.36e-3)" "unprognostic (3.68e-3)" "unprognostic (2.42e-1)" "unprognostic (1.02e-3)" "unprognostic (1.25e-2)" "unprognostic (2.23e-1)" "unprognostic (2.48e-1)" "unprognostic (3.08e-2)" 491.9 179.3 61.5 241.5 78.2 81.5 216.2 75.0 90.9 259.2 68.3 265.3 147.4 330.4 171.7 168.6 172.0 347.4 390.3 60.2 74.3 180.4 287.1 233.6 118.0 88.4 80.6 157.1 135.3 145.4 59.8 459.5 88.9 248.1 223.6 27.7 130.7 427.7 157.9 92.2 150.8 710.0 76.6 204.7 160.1 91.2 86.4 77.5 161.5 194.5 106.2 357.4 119.1 88.9 638.0 907.0 495.4 559.6 1183.4 1019.5 398.1 2063.9 1239.6 999.0 903.9 215.9 1478.2 164.5 354.1 1830.9 638.0 438.9 149.1 1204.1 1122.0 163.1 112.7 195.8 416.3 253.6 826.4 48.3 195.5 1027.7 658.2 1040.8 426.0 2711.1 1263.6 81.0 136.6 76.5 1700.8 109.0 80.1 46.7 107.4 200.6 428.2 52.0 357.0 30.9 1454.8 186.2 108.0 271.4 649.9 114.6 498.2 813.7 153.9 175.0 1362.6 1280.0 712.2 904.2 719.7 64.7 14.8 91.2 956.6 198.2 518.5 7.5 35.1 16.1 83.4 69.8 22.8 109.6 191.8 138.7 33.9 40.3 24.9 68.4 9.0 90.3 108.2 11.4 266.8 117.2 61.5 78.2 75.0 90.9 60.2 74.3 88.4 80.6 88.9 76.6 86.4 88.9 631.5 342.9 143.8 26.4 118.0 546.7 435.5 531.6 208.3 32.8 147.1 307.5 210.8 241.6 268.1 226.2 31.3 210.3 217.8 179.8 13.7 1206.9 6.6 194.6 437.9 421.1 193.3 153.0 37.2 411.3 515.2 374.7 95.8 406.5 88.7 561.8 375.9 268.1 179.8 38.7 52.4 97.4 213.6 170.1 206.7 18.3 254.5 217.8 343.3 67.5 119.4 72.0 111.2 42.7 66.8 1393.7 128.5 601.8 181.2 412.5 75.6 68.7 171.5 45.5 637.7 236.3 724.0 10.1 76.0 84.4 170.5 219.7 211.3 225.6 127.0 296.1 ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Group enriched" "Detected in many" 6 "dendritic cells: 417.6;Hofbauer cells: 652.4;Kupffer cells: 485.9;Langerhans cells: 259.1;Macrophages: 527.4;monocytes: 463.8;NK-cells: 959.9;T-cells: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "THP-1: 812.4;U-937: 615.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" 54.5 23.2 8.2 175.2 9.5 376.2 15.4 13.1 9.3 15.5 11.7 25.2 23.8 8.5 2.8 16.2 17.0 36.4 11.8 7.7 14.2 8.4 23.4 78.0 169.1 29.5 19.9 7.2 11.3 5.1 4.6 44.4 28.1 8.8 13.9 1.1 19.5 9.2 6.8 9.3 32.8 46.4 23.9 137.2 29.1 5.9 26.2 87.2 7.3 7.6 68.4 46.3 5.9 50.4 1.9 4.8 0.0 0.0 0.0 0.3 1.7 0.0 2.7 0.1 0.0 0.4 0.4 17.9 128.1 0.2 0.6 0.5 0.0 0.2 0.0 1.5 1.4 18.2 0.0 3.2 0.1 106.6 27.5 1.6 0.1 0.5 0.3 0.1 0.3 58.0 0.7 1.4 7.0 4.0 117.8 126.1 0.4 0.4 2.4 1.5 23.2 64.6 4.7 0.0 0.6 1.3 3.4 2.5 1.7 0.0 0.4 812.4 2.5 0.2 6.6 0.4 3.7 0.8 5.9 2.9 0.1 615.0 0.9 186.6 1848.8 1224.1 726.7 1144.9 326.6 86.1 349.7 506.5 1031.4 115.2 233.1 396.5 1386.1 585.5 1183.5 165.5 288.0 3034.2 8.2 9.5 13.1 9.3 7.7 14.2 29.5 19.9 28.1 23.9 26.2 50.4 7.1 16.0 29.6 0.3 81.7 5.5 0.5 9.6 0.6 0.0 4.1 6.5 4.0 14.3 18.6 5.5 0.0 4.0 417.6 0.3 0.0 3.4 1.0 0.6 0.5 16.8 0.0 19.6 0.5 0.4 4.8 5.3 2.6 0.7 24.1 8.2 9.7 8.6 652.4 0.0 0.3 0.2 2.0 485.9 259.1 2.8 0.6 527.4 5.4 27.2 463.8 0.4 959.9 0.0 0.2 0.6 0.1 1.5 50.5 0.6 1.8 4.2 3.6 0.8 6.6 2.1 3.2 0.2 1.0 0.9 5.1 5.6 254.5 0.0 0.3 0.7 ITGB3 "CD61, GP3A, GPIIIa" ENSG00000259207 "Integrin subunit beta 3" P05106 17 47253827-47313743 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 51.4" "Cell type enhanced" "Detected in some" "Early spermatids: 3.9;Late spermatids: 8.8;Macrophages: 15.8;Proximal tubular cells: 4.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 6 "melanoma: 7.5;renal cancer: 3.6;thyroid cancer: 11.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 19 "basophil: 5.4;neutrophil: 2.5" "Lineage enriched" "Detected in single" 26 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "EFO-21: 167.8;HEL: 163.4;RPTEC TERT1: 109.8;U-87 MG: 78.3;WM-115: 255.9" HPA027852 Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 38000000 "Cluster 34: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" Nucleoplasm "HPA027852: AB_10601760" "unprognostic (1.13e-2)" "unprognostic (1.97e-3)" "unprognostic (2.47e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-2)" "unprognostic (6.04e-3)" "unprognostic (3.70e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-1)" "unprognostic (6.35e-2)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.03e-2)" "unprognostic (2.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-3)" 8.0 0.6 0.3 9.5 0.7 6.2 5.3 0.7 1.0 3.8 1.0 16.9 3.5 13.2 2.6 4.2 7.6 3.5 5.5 0.5 0.8 15.0 3.4 5.6 0.9 2.3 1.0 1.5 0.7 1.2 1.2 4.5 2.0 4.8 7.0 0.9 2.6 16.1 1.5 2.7 5.8 22.9 1.2 2.9 3.8 2.5 1.2 0.3 51.4 2.4 1.2 9.6 2.6 1.1 0.1 1.5 0.7 0.1 8.6 3.8 0.1 4.7 23.1 9.6 8.6 0.3 0.1 0.6 167.8 1.2 13.4 0.0 0.1 0.0 12.6 3.4 0.0 163.4 0.5 0.0 7.8 0.0 0.2 3.4 0.0 54.6 1.4 6.7 43.6 2.5 0.5 0.3 2.1 0.0 1.0 0.1 0.1 0.0 0.8 0.0 4.2 0.0 109.8 0.2 0.0 0.5 5.6 0.0 33.2 8.8 0.1 0.2 47.1 2.1 2.4 1.3 11.7 0.2 0.1 1.1 78.3 0.0 255.9 5.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.1 0.1 0.1 0.0 6.8 0.3 0.7 0.7 1.0 0.5 0.8 2.3 1.0 2.0 1.2 1.2 1.1 1.3 0.0 0.0 0.0 0.5 0.1 0.2 0.9 0.0 0.0 0.1 0.3 0.8 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 3.9 0.8 0.9 3.1 0.0 0.0 0.4 0.4 0.0 2.1 0.0 0.9 0.0 0.6 1.8 0.7 0.8 0.0 0.6 0.0 0.0 0.3 0.7 8.8 0.3 15.8 0.0 1.0 0.4 0.0 0.0 0.0 0.4 1.5 0.0 1.2 0.0 0.3 0.0 4.6 0.2 0.0 6.6 0.3 2.1 0.0 2.0 0.1 0.4 1.2 0.3 0.4 0.0 0.2 ITGB7 ENSG00000139626 "Integrin subunit beta 7" P26010 12 53191323-53207282 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.0" "Cell type enhanced" "Detected in many" "B-cells: 45.1;dendritic cells: 62.3;NK-cells: 134.9;Plasma cells: 115.9;T-cells: 62.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 99 "Karpas-707: 4821.4;RPMI-8226: 3980.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA042277 Approved "Plasma membrane,Cytosol" NA NA 130000 "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA042277: AB_10793877" "unprognostic (5.34e-2)" "unprognostic (4.47e-2)" "unprognostic (2.80e-3)" "unprognostic (1.40e-2)" "unprognostic (6.57e-4)" "unprognostic (3.51e-5)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (3.58e-1)" "unprognostic (2.18e-1)" "unprognostic (9.63e-3)" "unprognostic (3.36e-1)" "unprognostic (1.02e-2)" "unprognostic (2.16e-1)" "unprognostic (6.95e-2)" "unprognostic (9.34e-2)" "unprognostic (2.47e-4)" 1.6 1.4 1.7 20.0 1.8 15.5 1.9 1.7 2.2 2.7 2.0 9.7 11.7 1.6 2.8 6.4 2.9 3.9 0.8 1.5 2.0 4.7 5.3 6.6 29.2 2.3 1.8 0.7 1.2 0.7 1.3 0.5 2.0 1.7 9.5 1.0 4.1 2.3 0.7 11.9 17.3 2.4 1.9 30.0 8.2 0.6 2.8 8.6 3.1 0.6 26.5 6.2 2.9 2.1 0.1 0.0 0.0 0.3 0.1 0.7 1.4 0.5 0.0 0.0 0.5 0.0 2.1 44.5 0.8 0.0 0.0 9.4 0.0 0.3 0.0 16.5 0.0 1.5 0.0 0.0 0.0 1.0 18.5 1.0 1.8 0.2 0.1 0.6 0.0 2.2 0.4 4821.4 0.0 1.6 0.9 7.0 0.3 41.7 0.1 1.8 0.0 3980.8 0.0 1.2 1.9 0.6 0.1 1.8 0.5 0.0 0.8 10.4 0.0 0.3 0.6 0.9 0.0 8.9 17.9 3.8 3.8 2.6 1.6 80.7 5.6 97.7 52.0 1.4 38.2 28.1 51.8 63.0 44.5 29.8 44.5 44.4 1.5 23.7 0.4 11.9 71.8 17.3 1.7 1.8 1.7 2.2 1.5 2.0 2.3 1.8 2.0 1.9 2.8 2.1 1.0 3.2 5.5 1.3 45.1 2.2 0.3 1.7 3.4 0.1 1.3 1.0 0.5 2.8 1.3 7.3 4.2 0.1 62.3 0.6 7.9 0.3 0.0 1.2 0.4 0.9 0.0 2.1 0.0 0.5 0.1 1.3 2.6 2.4 29.2 0.1 0.4 2.2 13.3 0.0 0.1 0.5 0.0 3.7 10.3 0.3 0.0 17.3 7.2 1.9 13.3 7.0 134.9 0.0 0.5 0.9 1.7 0.0 115.9 0.2 0.0 7.6 0.2 0.8 0.0 1.0 8.2 0.2 1.4 3.3 3.7 0.1 62.5 0.1 1.2 1.4 ITGBL1 "OSCP, TIED" ENSG00000198542 "Integrin subunit beta like 1" O95965 13 101452593-101720856 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 76.1;Skeletal myocytes: 93.0" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 208.3;ASC TERT1: 138.7;fHDF/TERT166: 345.3;LHCN-M2: 311.8" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 56.9" "Secreted - unknown location" NA NA 37000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.70e-1)" "unprognostic (2.12e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.12e-4)" "unprognostic (1.45e-1)" "unprognostic (3.18e-1)" "unprognostic (2.54e-1)" "unprognostic (1.86e-1)" "unprognostic (8.84e-2)" "unprognostic (2.16e-2)" "unprognostic (9.50e-2)" "unprognostic (1.13e-5)" "unprognostic (1.44e-2)" "unprognostic (2.55e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.70e-4)" 16.9 9.2 1.8 0.7 1.8 0.1 18.0 2.6 2.3 23.8 2.5 1.5 0.5 2.0 0.5 9.7 4.9 38.3 18.3 1.9 3.6 2.7 7.7 25.4 1.3 3.9 2.3 5.3 7.9 5.6 10.3 33.4 4.3 4.0 2.5 0.1 11.7 4.4 4.5 13.2 0.5 4.1 3.5 4.0 7.2 2.5 2.2 0.9 8.4 14.9 4.3 17.8 10.0 6.5 4.2 0.3 0.0 0.0 208.3 138.7 0.0 65.8 67.7 29.3 18.7 0.0 2.4 0.0 0.3 345.3 13.9 70.9 0.0 24.1 46.0 0.0 0.0 21.3 0.6 0.0 21.7 0.0 0.0 59.3 1.5 16.8 46.6 55.3 76.8 0.0 1.5 0.7 311.8 0.0 0.0 0.0 0.0 0.0 24.0 0.1 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 8.8 24.0 33.2 27.3 0.1 8.3 0.0 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 2.6 2.3 1.9 3.6 3.9 2.3 4.3 3.5 2.2 6.5 1.9 3.2 0.5 5.5 0.1 4.0 0.1 1.3 0.6 1.8 4.2 19.0 0.5 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.5 4.5 0.5 7.7 1.2 0.0 0.0 3.6 0.2 0.8 76.1 5.6 1.1 0.0 0.0 8.6 0.5 0.7 5.0 6.7 0.0 0.0 0.0 4.7 2.1 0.0 0.8 5.4 13.1 0.0 0.5 0.0 2.0 5.0 1.1 0.0 8.2 0.6 0.2 0.0 0.1 0.0 0.7 0.0 93.0 4.8 11.6 8.4 0.7 2.4 0.8 0.4 1.2 0.0 0.2 ITIH1 "H1P, IATIH, ITIH" ENSG00000055957 "Inter-alpha-trypsin inhibitor heavy chain 1" P19827 3 52777595-52792068 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 782 "liver: 1504.9" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 1087.0" "Cancer enriched" "Detected in some" 598 "liver cancer: 329.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 5.3;Hep G2: 1.7;HL-60: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041639, HPA042049" Approved Approved Vesicles "Secreted to blood" NA NA 4490000 59000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA041639: AB_10796349, HPA042049: AB_10797379" "unprognostic (1.87e-4)" "unprognostic (1.31e-3)" "unprognostic (2.38e-1)" "unprognostic (8.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.64e-3)" "prognostic favorable (1.89e-5)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-2)" "unprognostic (4.53e-4)" "unprognostic (4.02e-3)" "unprognostic (5.70e-3)" "unprognostic (2.08e-1)" "unprognostic (2.24e-2)" 0.8 0.3 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.2 1504.9 0.1 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 1.9 0.4 0.4 0.0 0.4 0.0 0.1 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.1 0.0 29.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 18.5 1087.0 0.1 0.0 0.0 0.0 0.0 20.2 0.0 1.7 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.1 ITIH2 H2P ENSG00000151655 "Inter-alpha-trypsin inhibitor heavy chain 2" P19823 10 7703316-7749520 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 668 "liver: 2156.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 489.6" "Cancer enriched" "Detected in many" 279 "liver cancer: 626.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 453 "Hep G2: 1103.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA059150 Supported Approved "Golgi apparatus" "Secreted to blood" NA NA 32000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "HPA059150: AB_2683930" "unprognostic (4.82e-2)" "unprognostic (6.10e-2)" "unprognostic (2.48e-2)" "unprognostic (1.21e-2)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" "prognostic favorable (1.48e-4)" "unprognostic (1.37e-1)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (2.28e-1)" "unprognostic (2.02e-1)" "unprognostic (2.10e-8)" "unprognostic (9.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.35e-1)" "unprognostic (4.46e-4)" 0.1 0.2 0.3 0.1 1.1 0.1 3.0 1.6 3.2 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.1 0.6 1.0 0.8 2156.1 0.6 0.1 0.6 0.5 0.0 0.2 0.0 1.7 0.1 0.6 0.0 0.0 0.3 0.0 0.0 0.8 0.4 0.0 0.0 0.9 0.3 0.5 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.6 1103.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 2.4 0.0 0.1 0.7 0.0 0.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.1 1.6 3.2 0.6 1.0 0.6 0.5 0.6 0.9 0.9 0.7 0.1 0.0 2.2 0.7 1.0 0.0 0.0 0.0 0.0 0.0 2.8 0.3 0.4 117.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 4.1 0.0 0.0 0.6 0.0 2.7 3.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 8.2 489.6 0.1 0.0 1.4 0.0 0.0 9.4 0.0 2.1 0.0 0.0 0.0 18.7 0.0 0.0 0.0 1.5 1.8 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 ITIH3 H3P ENSG00000162267 "Inter-alpha-trypsin inhibitor heavy chain 3" Q06033 3 52794768-52809009 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 97 "liver: 792.7" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 1183.8" "Cancer enriched" "Detected in some" 247 "liver cancer: 273.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "Hep G2: 17.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA017373 Approved "Secreted to blood" NA NA 9100000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA017373: AB_1851954" "unprognostic (2.07e-2)" "unprognostic (5.79e-2)" "unprognostic (1.89e-1)" "unprognostic (3.30e-4)" "unprognostic (4.28e-2)" "unprognostic (3.26e-2)" "unprognostic (5.97e-2)" "unprognostic (6.07e-2)" "unprognostic (1.49e-1)" "unprognostic (7.05e-2)" "unprognostic (1.04e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.49e-8)" "unprognostic (2.09e-4)" "unprognostic (1.70e-1)" "unprognostic (2.55e-2)" "unprognostic (9.31e-2)" 5.0 0.7 0.5 0.9 0.7 0.0 2.1 0.5 0.8 5.3 0.4 1.1 0.3 3.5 1.7 1.3 3.4 1.2 0.7 0.5 0.4 0.7 792.7 3.0 2.5 0.4 0.4 2.8 0.3 0.1 0.3 1.7 0.5 1.1 1.0 0.1 0.4 2.4 0.6 1.3 1.2 1.2 0.4 8.1 1.2 3.5 0.4 0.2 1.2 0.4 1.7 1.4 2.3 0.5 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.5 0.8 0.5 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.1 0.0 0.0 0.0 21.6 0.1 0.0 0.0 0.0 0.5 0.1 1.4 0.8 78.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 0.1 0.1 3.5 0.0 90.9 0.0 0.0 0.1 2.1 0.0 0.0 0.0 12.3 66.4 1183.8 0.0 0.0 0.0 0.0 0.0 85.1 0.3 132.0 1.2 0.1 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 9.1 0.4 0.3 0.0 0.1 0.3 3.6 19.2 0.0 0.1 ITIH4 "H4P, IHRP, ITIHL1" ENSG00000055955 "Inter-alpha-trypsin inhibitor heavy chain 4" Q14624 3 52812962-52830688 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "liver: 1863.4" "Group enriched" "Detected in many" 5 "Early spermatids: 119.2;Hepatocytes: 134.6;Late spermatids: 126.5" "Cancer enriched" "Detected in single" 27 "liver cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.4;JURKAT: 2.0;U-266/70: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001835, HPA003948, CAB072872" Enhanced Approved Vesicles "Secreted to blood" NA NA 3060000 58000000000 "Cluster 15: NK-cells - Transcription" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB072872: AB_2665724, HPA001835: AB_1079432, HPA003948: AB_1079433" "unprognostic (6.08e-2)" "unprognostic (4.45e-2)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "unprognostic (2.64e-1)" "unprognostic (1.96e-1)" "unprognostic (5.86e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-2)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-14)" "unprognostic (1.71e-3)" "unprognostic (2.96e-2)" "unprognostic (1.52e-1)" "unprognostic (4.21e-5)" 4.2 18.5 4.1 1.2 4.2 10.0 3.0 3.7 5.0 4.2 3.5 3.6 1.0 2.9 1.7 1.4 3.8 1.1 3.2 3.9 3.6 5.4 1863.4 4.9 1.7 3.9 3.8 2.4 48.9 0.1 4.3 0.7 3.9 4.0 1.0 3.3 2.1 1.8 40.3 2.5 3.4 1.5 3.6 7.4 3.9 1.8 3.8 2.2 5.2 2.8 1.2 5.3 3.3 3.9 0.0 0.1 0.4 0.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.2 0.1 0.4 0.0 0.0 0.2 2.4 0.1 1.0 0.0 1.2 0.4 1.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.0 0.3 0.8 0.0 0.1 0.2 0.3 0.4 0.1 0.0 0.8 0.3 0.0 0.2 0.3 0.0 0.4 0.3 0.0 0.1 0.4 0.5 0.3 0.1 0.0 0.4 0.4 0.0 3.0 1.4 0.2 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 4.1 4.2 3.7 5.0 3.9 3.6 3.9 3.8 3.9 3.6 3.8 3.9 0.7 0.0 1.1 22.5 0.9 0.8 0.3 0.3 0.0 10.0 0.6 1.3 1.1 2.8 0.8 0.0 12.5 0.0 0.4 0.1 0.0 0.3 119.2 0.7 0.7 0.8 0.0 8.4 11.6 2.6 0.0 0.6 1.1 0.4 0.0 2.7 2.5 134.6 0.5 5.0 8.6 0.2 0.0 2.2 1.0 126.5 1.2 1.3 0.0 5.6 1.9 2.3 2.1 3.0 3.1 2.3 0.5 1.9 0.7 0.2 0.0 0.3 0.3 6.0 6.6 6.2 2.4 1.3 1.5 0.0 0.3 0.3 1.2 3.2 0.1 0.1 ITIH5 MGC10848 ENSG00000123243 "Inter-alpha-trypsin inhibitor heavy chain 5" 10 7559270-7666998 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 282.7;Fibroblasts: 111.3;Microglial cells: 160.2;Smooth muscle cells: 110.1;Syncytiotrophoblasts: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "WM-115: 102.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038305 Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Vesicles "HPA038305: AB_10670662" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "unprognostic (3.11e-3)" "unprognostic (6.80e-2)" "unprognostic (1.80e-1)" "unprognostic (5.84e-3)" "unprognostic (1.63e-1)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (2.90e-1)" "unprognostic (5.80e-3)" "unprognostic (6.11e-2)" "unprognostic (1.36e-1)" "unprognostic (6.79e-3)" "unprognostic (2.00e-2)" "unprognostic (4.50e-2)" "unprognostic (3.48e-2)" 112.7 3.7 17.9 19.4 18.6 0.2 53.3 19.7 23.2 17.4 28.6 62.7 13.9 24.3 6.3 21.4 10.5 27.7 16.8 14.7 18.0 16.4 1.6 22.4 12.5 18.9 18.1 21.2 15.0 6.3 5.4 86.9 19.7 24.0 16.8 3.5 9.5 46.6 17.8 12.0 21.6 28.8 15.7 3.4 24.0 6.2 22.5 3.8 24.5 22.5 13.4 51.4 15.3 15.2 0.0 0.0 0.0 0.1 0.0 0.0 7.0 18.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.5 14.8 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.1 0.0 0.0 0.0 102.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 18.6 19.7 23.2 14.7 18.0 18.9 18.1 19.7 15.7 22.5 15.2 74.9 3.2 2.7 1.3 0.2 11.3 3.0 0.1 6.8 2.7 1.6 17.3 8.7 8.6 3.7 0.0 2.1 282.7 0.8 0.1 0.0 25.7 2.0 18.7 1.5 58.8 0.0 0.0 0.5 0.4 70.2 111.3 0.0 34.1 2.5 0.5 1.8 0.1 20.7 0.0 0.7 0.0 8.2 1.2 19.6 2.2 5.3 3.6 14.2 160.2 1.1 21.9 0.0 1.5 1.0 0.3 0.0 15.4 0.9 1.8 0.2 2.1 0.7 3.2 78.9 32.3 110.1 1.7 7.7 0.7 8.8 221.9 3.0 0.3 0.0 1.6 ITIH6 "ITIH5L, UNQ6369" ENSG00000102313 "Inter-alpha-trypsin inhibitor heavy chain family member 6" Q6UXX5 X 54748918-54798255 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "melanoma: 10.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "WM-115: 50.7" HPA000506 Uncertain "Secreted to blood" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 35: Glandular cells - Unknown function" "HPA000506: AB_2666007" "unprognostic (3.40e-1)" "unprognostic (1.04e-1)" "unprognostic (9.73e-3)" "unprognostic (7.24e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-3)" "unprognostic (9.81e-2)" "unprognostic (2.66e-1)" "unprognostic (1.02e-1)" "unprognostic (6.33e-2)" "unprognostic (4.14e-4)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (2.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 50.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ITLN1 "FLJ20022, hIntL, HL-1, ITLN, LFR" ENSG00000179914 "Intelectin 1" Q8WWA0 1 160876540-160885180 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 757.3;intestine: 1247.8" "Cell type enriched" "Detected in many" 14 "Intestinal goblet cells: 1818.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 61.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "intermediate monocyte: 9.2;non-classical monocyte: 24.1" "Lineage enriched" "Detected in many" 17 "monocytes: 24.1" "Group enriched" "Detected in some" 4 "HEL: 2.6;HL-60: 1.9;OE19: 7.2;U-937: 7.1" "Not detected" "Not detected" "CAB012652, HPA063275, HPA067326" Enhanced "Secreted to blood" NA NA 294000000 6400000 "Cluster 51: Monocytes - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB012652: , HPA063275: AB_2684974, HPA067326: AB_2732764" "unprognostic (9.69e-2)" "unprognostic (2.48e-2)" "unprognostic (1.31e-3)" "unprognostic (2.28e-1)" "unprognostic (1.79e-2)" "unprognostic (1.11e-1)" "unprognostic (1.59e-2)" "unprognostic (1.70e-1)" "unprognostic (5.22e-3)" "unprognostic (1.66e-2)" "unprognostic (4.38e-1)" "unprognostic (9.96e-2)" "unprognostic (3.67e-1)" "unprognostic (8.99e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-2)" 757.3 0.3 0.0 26.4 0.0 2.6 0.5 0.0 0.0 0.3 0.0 444.2 272.7 0.5 2.1 0.4 6.2 0.8 233.8 0.0 0.0 35.5 3.1 40.3 0.3 0.0 0.0 9.7 3.3 0.0 0.4 1.3 0.0 0.6 1247.8 0.0 24.9 3.3 0.7 0.2 415.7 7.7 0.0 2.5 15.9 2.0 0.0 0.7 0.6 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 1.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.2 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 7.1 0.0 0.0 0.5 0.0 0.0 9.2 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.2 0.0 24.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 4.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 26.6 71.4 2.1 3.7 0.0 0.1 0.1 46.4 0.0 37.7 0.8 0.0 0.0 4.3 18.0 4.0 0.0 3.6 1.4 87.8 8.6 0.0 1.3 1.4 60.7 1.9 0.8 0.0 0.0 1818.6 0.0 124.7 0.0 0.7 14.6 1.8 0.0 0.0 0.3 0.0 1.0 0.0 0.0 7.3 17.7 3.0 0.0 0.3 15.4 0.1 0.8 0.0 0.0 0.0 10.8 0.1 0.9 0.0 0.0 0.3 2.1 15.3 59.4 0.1 ITLN2 HL-2 ENSG00000158764 "Intelectin 2" Q8WWU7 1 160945025-160954809 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "intestine: 408.3" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 1: 76.9" "Group enriched" "Detected in many" 4 "colorectal cancer: 2.8;testis cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 11.9;HHSteC: 1.9;HMC-1: 3.4;SK-MEL-30: 4.0;SuSa: 3.8" "Low region specificity" "Detected in all" "HPA006683, HPA067326" Enhanced "Secreted to digestive system" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 11: Alveolar cells - Smell perception" "HPA006683: AB_2129681, HPA067326: AB_2732764" "unprognostic (1.42e-1)" "unprognostic (9.62e-3)" "unprognostic (4.61e-2)" "unprognostic (7.45e-2)" "unprognostic (2.25e-1)" "unprognostic (6.84e-4)" "unprognostic (2.47e-2)" "unprognostic (5.74e-2)" "unprognostic (1.31e-2)" "unprognostic (1.36e-1)" "unprognostic (5.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.49e-1)" "unprognostic (2.31e-1)" "unprognostic (4.91e-2)" 6.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 238.7 0.1 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.1 0.4 11.7 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.1 0.0 0.2 408.3 0.0 0.0 0.0 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 1.9 0.0 3.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.7 0.0 0.0 4.0 3.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.9 5.3 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.4 0.3 1.4 0.0 0.2 0.0 0.4 11.0 0.3 0.1 0.0 0.0 5.0 0.0 0.3 0.0 0.2 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 5.3 0.0 0.6 14.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.3 6.3 17.5 0.4 ITPKA "IP3-3KA, IP3KA" ENSG00000137825 "Inositol-trisphosphate 3-kinase A" P23677 15 41493393-41503551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.5;intestine: 18.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 51.4;Early spermatids: 45.4;Gastric mucus-secreting cells: 34.1;Late spermatids: 166.4;Proximal enterocytes: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "MAIT T-cell: 1.4" "Lineage enriched" "Detected in single" 11 "T-cells: 1.4" "Cell line enhanced" "Detected in many" "Hep G2: 33.6;OE19: 18.2" "Low region specificity" "Detected in all" HPA040454 Enhanced Approved Approved "Vesicles,Plasma membrane" No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "Plasma membrane" "HPA040454: AB_10672897" "unprognostic (5.91e-2)" "unprognostic (2.16e-3)" "unprognostic (4.19e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.77e-4)" "unprognostic (2.25e-2)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.58e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (3.76e-9)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-3)" "unprognostic (2.10e-2)" 0.2 7.3 21.4 0.7 26.7 0.4 0.2 13.8 36.5 1.3 10.9 10.7 17.6 0.3 0.1 0.3 0.5 0.2 2.6 28.7 12.4 0.2 1.7 0.5 0.1 10.9 12.0 0.3 1.9 2.0 0.4 0.3 11.6 0.8 2.7 0.3 1.4 0.3 4.4 0.4 18.1 0.3 11.3 0.2 10.9 10.4 12.1 0.0 0.2 0.0 0.0 0.6 0.9 20.4 7.1 1.9 0.3 7.9 0.0 2.5 14.3 4.3 3.4 2.8 2.9 16.3 0.3 0.0 3.5 0.4 6.3 0.8 3.4 0.3 0.2 6.6 4.3 9.9 4.7 33.6 12.6 3.4 0.5 0.2 0.2 2.7 0.8 1.6 0.2 1.3 12.9 1.9 1.0 4.7 0.3 6.5 0.9 18.2 5.6 1.7 1.4 0.6 0.3 0.4 0.7 1.5 3.2 0.0 0.3 0.0 0.9 5.0 0.3 6.9 7.1 7.7 11.8 1.0 10.8 0.0 12.6 13.2 2.3 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 21.4 26.7 13.8 36.5 28.7 12.4 10.9 12.0 11.6 11.3 12.1 20.4 0.1 0.0 0.0 3.3 0.5 0.1 0.3 0.1 0.0 0.0 0.3 0.0 1.4 0.0 0.1 0.0 0.0 0.6 0.1 51.4 0.0 0.1 45.4 0.3 2.4 0.5 0.0 0.8 23.7 0.7 0.5 0.3 34.1 0.3 0.0 1.0 0.4 0.3 0.2 0.0 0.8 12.0 0.0 0.0 0.0 166.4 2.5 0.4 0.0 1.9 0.0 7.9 0.0 1.5 2.9 0.8 16.1 1.5 0.1 0.1 35.8 0.1 0.1 0.2 6.6 0.3 0.5 14.4 4.9 0.0 0.0 0.1 0.4 0.1 18.7 0.2 ITPRID1 "CCDC129, FLJ38344" ENSG00000180347 "ITPR interacting domain containing 1" Q6ZRS4 7 31514071-31658720 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 15.9;salivary gland: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA024103 Uncertain Uncertain Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 9: U-2 OS - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA024103: AB_1846132" "unprognostic (1.11e-2)" "unprognostic (1.39e-1)" "unprognostic (1.57e-1)" "unprognostic (1.78e-5)" "unprognostic (9.72e-3)" "unprognostic (1.78e-1)" "unprognostic (3.89e-2)" "unprognostic (6.42e-3)" "unprognostic (1.01e-1)" "unprognostic (5.77e-2)" "unprognostic (1.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.99e-1)" "unprognostic (1.53e-1)" 0.1 0.0 2.7 0.1 3.9 0.1 1.6 11.0 0.4 1.7 0.0 0.5 1.1 0.6 0.1 0.0 0.0 0.1 0.0 0.7 9.7 0.1 0.0 0.0 0.0 4.8 15.9 0.0 0.1 0.0 0.1 0.0 9.2 0.1 0.1 0.1 5.3 0.0 0.0 2.3 0.5 0.6 1.4 0.0 0.4 1.3 13.2 0.0 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 3.9 11.0 0.4 0.7 9.7 4.8 15.9 9.2 1.4 13.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IZUMO1R "Folbp3, FOLR4, JUNO" ENSG00000183560 "IZUMO1 receptor, JUNO" A6ND01 11 94305592-94307721 "Predicted intracellular proteins, Transporters" Fertilization Receptor "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (5.56e-3)" "unprognostic (1.37e-1)" "unprognostic (7.22e-3)" "unprognostic (8.39e-2)" "unprognostic (2.92e-3)" "unprognostic (2.47e-1)" "unprognostic (5.08e-2)" "unprognostic (8.61e-2)" 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IZUMO4 C19orf36 ENSG00000099840 "IZUMO family member 4" Q1ZYL8 19 2096429-2099593 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "testis: 443.1" "Group enriched" "Detected in many" 51 "Early spermatids: 1750.8;Late spermatids: 2537.9;Spermatocytes: 824.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Karpas-707: 8.5;RPMI-8226: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048496 Enhanced "Secreted in male reproductive system" NA NA "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA048496: AB_2680419" "unprognostic (2.75e-3)" "unprognostic (1.10e-2)" "unprognostic (3.65e-2)" "prognostic favorable (7.08e-4)" "unprognostic (1.40e-1)" "unprognostic (2.18e-5)" "unprognostic (2.67e-2)" "unprognostic (1.02e-3)" "unprognostic (1.30e-1)" "unprognostic (2.48e-1)" "prognostic favorable (1.69e-4)" "unprognostic (2.12e-1)" "unprognostic (6.58e-5)" "unprognostic (6.38e-2)" "unprognostic (2.17e-1)" "unprognostic (5.68e-1)" "unprognostic (7.51e-3)" 2.9 1.9 15.2 1.2 15.3 0.5 3.3 15.1 20.9 2.7 15.1 3.0 0.5 2.6 2.5 2.6 5.1 1.9 3.0 14.6 14.4 4.3 5.4 2.1 1.8 15.1 15.7 6.5 8.6 0.8 10.1 0.4 15.2 7.5 0.8 2.9 2.4 2.4 2.6 2.5 2.0 0.7 14.9 1.6 3.9 443.1 15.6 1.7 4.6 1.2 2.2 2.5 2.3 15.7 0.6 0.5 0.3 2.7 1.1 1.2 0.3 0.4 0.6 0.4 0.0 0.2 0.5 0.4 0.6 0.6 0.0 0.5 0.0 2.9 0.1 1.2 0.2 0.0 1.1 0.8 3.2 0.0 0.4 0.5 1.1 0.7 0.8 0.9 0.0 1.5 0.0 8.5 1.1 0.1 0.8 0.2 0.3 1.1 0.7 0.7 0.0 10.9 1.2 0.3 0.4 0.7 0.4 0.9 0.4 0.2 0.5 1.0 0.0 0.3 0.1 0.1 0.2 0.9 1.1 0.8 1.4 0.9 0.2 0.0 0.7 0.6 0.6 1.1 1.5 2.7 2.1 1.6 0.9 0.7 1.7 0.7 1.6 0.5 1.6 1.2 2.2 0.9 15.2 15.3 15.1 20.9 14.6 14.4 15.1 15.7 15.2 14.9 15.6 15.7 1.0 0.0 0.0 31.0 10.3 2.4 4.1 32.8 4.0 3.4 2.5 2.3 1.5 5.7 19.7 9.2 8.4 0.5 2.6 2.0 5.9 2.5 1750.8 4.6 1.9 1.7 7.7 0.4 1.2 5.8 4.5 3.7 1.1 2.3 0.0 2.2 0.7 9.5 1.0 0.0 1.6 1.9 14.2 3.2 8.2 2537.9 28.6 4.3 12.4 0.0 11.3 6.6 1.0 1.5 28.0 1.8 0.7 19.9 8.2 6.8 1.9 11.1 12.1 8.6 6.6 2.6 2.1 824.6 14.3 6.3 1.7 1.6 5.6 2.4 4.4 7.0 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5129948 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.4;Inhibitory neurons: 122.3;Microglial cells: 106.8;Oligodendrocyte precursor cells: 69.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 132.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 132.5" "Group enriched" "Detected in many" 5 "ASC diff: 42.2;HDLM-2: 75.0;HEL: 154.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" No No "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: AB_2677151, HPA043870: AB_2678708" "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 15.6 7.6 3.2 19.2 3.7 21.7 8.9 6.3 9.1 8.5 1.1 6.7 6.5 11.3 8.6 8.8 8.0 10.5 24.5 2.7 3.1 6.8 4.5 10.9 18.2 3.3 1.8 11.5 3.8 6.5 2.9 11.0 2.0 6.8 6.5 12.8 4.0 6.2 9.8 11.2 7.7 9.5 3.5 17.6 13.4 9.8 1.7 7.5 4.8 8.9 12.7 11.7 9.1 3.9 6.8 3.7 3.7 6.3 42.2 12.4 1.1 9.1 8.6 7.2 4.6 1.2 2.0 0.3 2.1 5.4 5.4 2.3 4.4 5.1 4.9 75.0 1.4 154.7 7.6 1.7 10.0 10.5 7.1 9.5 2.1 2.8 4.5 7.6 6.6 5.1 10.9 17.4 11.6 2.2 2.9 12.8 3.3 3.3 4.3 5.1 8.2 2.2 4.7 3.5 4.2 2.4 2.6 3.5 2.8 3.6 2.0 15.4 13.1 10.2 3.6 10.7 6.4 3.1 6.4 1.5 13.6 4.7 5.3 132.5 20.5 38.2 5.6 20.1 4.5 5.6 4.1 3.1 26.5 4.9 2.2 2.8 19.2 9.6 16.4 9.7 4.5 7.7 3.2 3.7 6.3 9.1 2.7 3.1 3.3 1.8 2.0 3.5 1.7 3.9 14.3 16.0 7.9 31.6 12.9 9.7 3.3 4.9 10.8 8.0 5.2 3.4 30.0 0.0 6.7 7.3 8.4 1.9 13.9 11.7 1.9 3.3 8.6 5.1 11.2 9.4 3.0 19.8 93.4 3.9 0.9 8.9 38.7 5.6 14.0 11.4 4.6 1.9 14.2 8.4 122.3 4.5 0.0 33.6 28.8 7.1 23.6 38.9 5.4 106.8 49.5 12.6 8.2 69.9 42.3 7.0 20.9 33.4 10.7 3.0 3.9 3.3 7.1 11.2 0.0 9.7 12.5 15.0 5.5 11.6 8.4 3.4 10.4 5.1 4.1 4.5 JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.3;lymphoid tissue: 68.7" "Group enriched" "Detected in many" 4 "dendritic cells: 136.9;Kupffer cells: 125.8;Macrophages: 166.6;monocytes: 204.7;T-cells: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 3529.6" "Group enriched" "Detected in all" 5 "dendritic cells: 1017.6;granulocytes: 3529.6;monocytes: 1023.8" "Cell line enriched" "Detected in some" 5 "HMC-1: 28.0" "Region enriched" "Detected in many" 11 "cerebellum: 58.0" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: AB_2680209" "unprognostic (3.91e-3)" "unprognostic (1.55e-3)" "unprognostic (3.00e-2)" "unprognostic (1.28e-3)" "unprognostic (2.87e-3)" "prognostic favorable (3.11e-4)" "unprognostic (2.80e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (8.69e-2)" "unprognostic (5.08e-1)" "unprognostic (6.43e-3)" "unprognostic (8.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.58e-2)" 13.9 4.5 0.9 68.7 1.0 20.9 5.6 2.4 2.1 5.6 2.3 16.8 17.8 3.5 1.5 8.5 4.3 20.4 3.2 0.7 0.9 3.4 9.8 43.3 31.1 1.3 0.9 1.8 2.9 1.0 1.6 7.8 1.0 4.4 22.7 0.3 2.9 3.6 1.2 4.6 32.1 15.3 1.0 60.0 9.4 1.5 1.0 24.3 2.9 7.8 31.6 24.9 3.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.9 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 2.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.3 3.1 0.4 3.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 137.4 1023.8 3529.6 60.1 616.5 386.5 7.1 107.4 113.7 1017.6 2.9 124.7 103.1 2121.1 24.3 310.3 765.1 191.3 844.1 0.9 1.0 2.4 2.1 0.7 0.9 1.3 0.9 1.0 1.0 1.0 1.1 1.2 6.4 34.2 0.0 6.9 0.0 0.2 0.0 0.0 0.3 0.9 1.3 0.0 2.8 5.6 1.8 0.0 0.3 136.9 0.9 0.0 0.1 1.0 0.4 0.2 1.3 0.0 5.0 0.0 0.4 0.4 1.8 2.6 0.6 15.2 0.0 5.7 2.8 31.0 0.0 0.0 0.2 0.0 125.8 0.0 1.1 0.0 166.6 0.0 0.0 204.7 0.0 9.2 0.0 0.0 0.1 0.1 0.0 6.3 0.1 0.6 0.8 2.2 0.2 0.0 0.4 0.5 2.2 5.9 0.2 0.0 0.4 56.0 0.0 0.1 0.2 JCHAIN "IGCJ, IGJ, JCH" ENSG00000132465 "Joining chain of multimeric IgA and IgM" P01591 4 70655541-70681817 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 3028.0;intestine: 7979.6;stomach 1: 5916.2" "Cell type enriched" "Detected in many" 16 "Plasma cells: 101294.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 121 "memory B-cell: 4173.0;naive B-cell: 2555.1;plasmacytoid DC: 3578.1" "Group enriched" "Detected in all" 137 "B-cells: 4173.0;dendritic cells: 3578.1" "Cell line enhanced" "Detected in many" "Daudi: 3953.8;Karpas-707: 2117.6;RPMI-8226: 4469.2;U-266/70: 8794.0;U-266/84: 3519.2;U-698: 4949.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034436, HPA044132" Enhanced "Secreted to blood" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB034436: AB_2233368, HPA044132: AB_2678826" "prognostic favorable (1.81e-6)" "unprognostic (1.45e-3)" "unprognostic (7.44e-3)" "unprognostic (1.82e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.56e-7)" "unprognostic (2.37e-2)" "unprognostic (2.70e-2)" "unprognostic (6.30e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.43e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.96e-1)" 130.2 76.6 0.7 1089.0 0.8 76.3 3028.0 0.4 3.0 205.2 3.1 7979.6 6145.8 94.2 25.0 654.4 115.0 492.4 45.6 0.4 1.4 43.3 116.8 620.2 1033.5 1.9 1.0 183.5 78.3 2.1 2.0 2.4 0.8 90.2 6426.5 0.3 2420.5 258.4 4.2 13.2 4277.1 200.3 7.0 819.4 5916.2 40.0 0.8 155.3 19.4 0.8 1746.7 1059.4 11.6 2.8 8.9 0.0 0.0 0.0 0.0 0.0 15.5 8.2 1.5 0.1 0.1 0.0 0.0 3953.8 3.3 12.7 0.1 6.6 0.0 0.0 0.6 2.1 0.0 3.3 0.0 0.0 0.0 3.3 9.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.4 2117.6 0.1 0.0 6.1 14.9 4.9 0.0 0.0 4.8 2.6 4469.2 0.0 0.0 3.3 15.7 3.7 2.6 2.7 0.0 0.8 6.8 3.9 9.9 11.8 4.9 6.3 8794.0 3519.2 4949.0 2.1 5.2 1.2 25.1 7.5 2.6 4.0 1.5 19.1 4173.0 2.5 3.8 6.6 2555.1 2.1 2.1 28.3 4.5 2.5 3578.1 2.6 1310.4 0.7 0.8 0.4 3.0 0.4 1.4 1.9 1.0 0.8 7.0 0.8 2.8 3.0 22.4 101.3 0.0 6154.9 0.0 28.2 0.0 8.6 0.0 11.7 1.9 2.2 15.7 8.1 0.0 0.0 0.1 700.0 5.1 0.0 0.0 0.5 0.0 0.1 38.1 7.3 139.0 0.0 0.0 0.1 48.8 228.8 0.0 79.5 0.1 66.4 24.6 0.3 0.0 0.0 5.3 0.0 35.8 0.0 0.3 0.0 42.0 0.0 0.0 3.9 0.0 6.2 0.0 0.0 0.0 5.1 0.0 101294.9 32.7 0.0 5.4 3.6 0.0 0.0 0.6 88.4 1.4 0.3 24.3 0.0 0.3 1487.8 0.0 3.5 0.6 JMJD8 C16orf20 ENSG00000161999 "Jumonji domain containing 8" Q96S16 16 681670-684528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (2.32e-2)" "unprognostic (1.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" "unprognostic (8.38e-2)" "unprognostic (1.03e-2)" "unprognostic (2.87e-1)" "unprognostic (4.79e-2)" "unprognostic (1.46e-1)" "unprognostic (1.50e-2)" "unprognostic (4.33e-2)" "unprognostic (1.63e-2)" "unprognostic (4.96e-3)" "unprognostic (5.53e-2)" "unprognostic (1.86e-1)" "unprognostic (3.29e-1)" "unprognostic (7.04e-2)" 24.5 25.9 19.9 14.5 19.8 17.4 17.3 18.9 23.7 25.9 31.4 21.0 17.5 24.9 30.5 24.7 29.6 21.3 37.2 20.1 20.0 23.0 23.1 19.2 15.6 22.4 19.9 23.7 41.0 31.5 14.0 15.4 19.9 23.8 10.9 7.5 40.5 32.6 13.1 22.4 15.3 21.9 20.2 15.7 19.3 15.7 21.8 15.1 32.2 14.5 10.8 22.3 15.5 19.6 21.5 59.5 14.6 63.0 59.8 22.9 8.5 26.3 49.0 26.9 30.6 33.7 49.8 7.4 28.2 38.1 0.3 36.8 17.4 34.2 10.2 28.6 27.5 15.5 32.5 4.3 26.4 35.7 27.3 27.3 22.8 18.0 20.9 20.1 41.4 14.9 20.0 40.8 16.1 52.8 18.8 28.1 34.9 35.5 25.3 22.6 3.8 76.3 54.0 13.4 26.1 28.3 38.1 43.0 9.3 8.4 44.3 33.3 21.8 1.9 21.5 12.8 15.6 23.7 14.5 9.5 7.1 16.6 22.5 0.2 6.3 0.1 5.0 5.2 6.5 3.9 5.7 5.0 7.3 4.6 4.8 4.8 0.2 3.4 4.8 4.9 6.7 3.0 19.9 19.8 18.9 23.7 20.1 20.0 22.4 19.9 19.9 20.2 21.8 19.6 33.8 9.6 21.3 5.5 14.0 13.8 21.1 7.2 14.2 15.2 34.5 37.6 11.5 21.5 11.3 23.9 14.6 35.8 19.8 26.2 29.4 46.4 21.2 22.5 23.9 19.8 21.6 9.2 4.3 42.0 40.7 29.1 15.8 18.8 2.5 29.9 15.4 26.8 20.5 16.8 5.0 17.0 8.2 16.1 17.3 50.1 23.3 13.9 17.8 1.9 15.5 31.8 17.5 3.5 4.4 31.0 10.7 29.3 19.9 23.3 15.4 30.6 11.0 21.2 0.0 16.3 32.0 22.4 13.0 18.8 19.5 30.4 14.2 39.2 23.5 18.3 JPT2 "C16orf34, FLJ13092, HN1L, KIAA1426, L11" ENSG00000206053 "Jupiter microtubule associated homolog 2" Q9H910 16 1678256-1702280 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 99.3;Ductal cells: 90.1;Endometrial ciliated cells: 107.3;Extravillous trophoblasts: 205.9;Glandular and luminal cells: 77.5;Pancreatic endocrine cells: 78.9;Syncytiotrophoblasts: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041888, HPA041908" Approved Approved "Plasma membrane,Cytosol" NA NA 76000 "Cluster 22: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA041888: AB_10793937, HPA041908: AB_10794160" "unprognostic (1.49e-2)" "unprognostic (1.76e-1)" "unprognostic (1.30e-3)" "prognostic favorable (7.85e-4)" "unprognostic (3.60e-1)" "unprognostic (2.37e-2)" "prognostic unfavorable (9.14e-4)" "unprognostic (1.10e-2)" "unprognostic (3.14e-2)" "unprognostic (1.50e-2)" "unprognostic (1.12e-3)" "unprognostic (4.27e-2)" "unprognostic (1.01e-2)" "unprognostic (9.22e-3)" "unprognostic (1.65e-1)" "unprognostic (4.14e-2)" "unprognostic (2.78e-2)" 21.2 17.0 12.7 18.6 21.1 11.3 36.4 33.2 19.8 39.5 14.1 32.7 21.9 21.1 17.9 47.7 63.4 13.6 20.3 12.0 16.3 48.8 41.1 20.0 19.9 58.0 27.8 19.8 29.6 20.9 15.1 48.1 46.9 47.9 30.5 4.6 26.6 18.2 17.5 31.3 24.2 19.5 28.4 12.8 28.2 18.1 25.6 35.5 27.7 14.0 31.3 31.2 25.9 51.7 148.1 147.5 168.4 93.9 23.9 39.3 151.9 143.6 44.8 117.7 99.8 194.5 188.3 94.6 107.8 71.1 116.4 141.9 223.5 194.2 135.7 77.2 135.2 78.4 80.2 111.4 36.7 93.5 44.8 28.1 121.6 116.4 149.6 64.9 75.7 85.4 187.5 37.0 68.6 169.5 117.1 46.6 185.3 164.4 112.0 212.7 159.3 136.2 186.2 82.5 156.1 85.6 214.9 205.3 66.5 161.1 250.3 59.6 87.9 113.9 201.1 54.8 141.1 31.5 136.3 198.8 35.8 71.5 170.5 2.1 3.7 4.1 5.2 3.3 7.2 4.8 5.8 4.2 2.8 7.6 6.3 5.4 0.3 6.8 1.7 6.6 5.8 4.4 12.7 21.1 33.2 19.8 12.0 16.3 58.0 27.8 46.9 28.4 25.6 51.7 11.9 25.6 10.6 0.0 2.7 0.0 0.0 0.0 0.0 0.0 33.3 23.4 0.0 0.0 12.4 9.2 0.0 99.3 4.5 0.0 43.0 90.1 0.0 107.3 19.2 8.5 0.0 0.0 0.0 25.6 205.9 7.4 0.0 77.5 2.5 23.4 0.0 0.0 41.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 28.4 0.0 0.0 0.0 0.0 78.9 0.0 0.0 1.2 0.0 0.0 26.0 27.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 168.7 3.6 18.9 0.0 0.0 KANSL2 "C12orf41, FLJ20436, NSL2" ENSG00000139620 "KAT8 regulatory NSL complex subunit 2" Q9H9L4 12 48653211-48682238 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038497, HPA038498" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Plasma membrane, Cytosol" "HPA038497: AB_10674685, HPA038498: AB_2676046" "unprognostic (3.87e-3)" "unprognostic (6.18e-2)" "unprognostic (3.67e-1)" "unprognostic (8.89e-2)" "unprognostic (5.37e-2)" "unprognostic (4.73e-2)" "prognostic unfavorable (4.98e-4)" "unprognostic (5.46e-2)" "unprognostic (1.35e-3)" "unprognostic (6.16e-2)" "unprognostic (6.75e-3)" "unprognostic (4.19e-3)" "unprognostic (8.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "prognostic favorable (4.32e-4)" 11.9 11.4 6.0 8.2 7.0 41.8 12.2 8.6 8.0 13.9 7.3 11.8 8.1 14.1 11.5 13.3 12.6 7.7 13.4 6.5 6.9 12.2 9.8 10.9 13.9 7.0 6.5 16.3 9.7 12.2 9.3 12.2 6.7 11.1 9.3 11.8 13.0 8.3 40.7 13.4 11.9 9.8 6.7 13.2 10.8 14.6 6.8 14.2 11.5 23.1 13.8 12.4 12.8 8.8 19.5 26.5 21.8 12.8 25.6 22.0 48.1 20.8 17.6 35.9 19.5 45.2 25.1 31.9 39.0 25.5 14.0 18.3 37.1 23.5 29.5 30.4 22.5 37.1 20.2 12.9 29.2 40.0 13.9 20.8 31.2 25.5 46.2 18.0 17.2 24.8 43.7 20.9 25.0 18.7 39.2 29.2 28.6 28.1 26.0 33.4 21.3 35.9 17.2 27.1 25.1 17.6 43.2 30.0 25.7 21.8 40.2 43.4 12.8 25.5 18.9 10.9 19.7 29.8 50.7 46.2 12.4 89.5 13.6 35.3 19.7 23.5 25.1 21.2 23.7 27.3 23.9 25.9 25.8 23.8 27.9 26.9 9.0 24.3 23.0 20.2 32.2 24.0 6.0 7.0 8.6 8.0 6.5 6.9 7.0 6.5 6.7 6.7 6.8 8.8 18.0 3.2 14.3 9.8 24.7 11.9 14.7 17.9 32.5 15.6 15.7 15.5 10.9 8.6 15.0 14.7 29.2 22.5 36.5 10.2 9.8 13.3 24.4 8.2 13.9 13.7 9.0 14.1 11.5 9.8 12.5 15.1 12.2 12.4 11.4 19.8 14.6 9.6 11.9 15.2 13.8 9.1 10.2 11.9 13.2 13.8 12.5 13.7 16.0 7.5 14.8 8.2 11.3 15.1 18.8 12.2 4.7 10.1 16.9 12.1 10.8 15.6 10.2 22.8 26.3 15.7 16.6 38.5 34.8 19.9 11.2 25.3 30.6 15.9 12.4 9.8 KANTR "LINC01155, Spasm" ENSG00000232593 "KDM5C adjacent transcript" X 53094145-53170914 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 3.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 15.9;Astrocytes: 13.4;Excitatory neurons: 20.5;Inhibitory neurons: 24.9;Oligodendrocytes: 16.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "JURKAT: 1.3" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (2.89e-1)" "unprognostic (1.66e-1)" "unprognostic (2.56e-2)" "unprognostic (1.17e-1)" "unprognostic (5.52e-2)" "unprognostic (2.18e-2)" "unprognostic (7.30e-2)" "unprognostic (4.79e-2)" "unprognostic (2.30e-3)" "unprognostic (2.54e-2)" "unprognostic (2.10e-2)" "unprognostic (1.46e-2)" "unprognostic (3.47e-6)" "unprognostic (1.51e-1)" "unprognostic (8.80e-2)" "unprognostic (2.78e-3)" "unprognostic (1.81e-3)" 0.0 0.1 2.5 0.0 2.0 0.7 0.1 2.8 2.5 0.2 0.0 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.0 1.9 2.9 0.1 0.0 0.1 0.0 1.6 2.5 0.3 0.0 0.0 0.4 0.1 1.9 0.1 0.0 0.3 0.1 0.0 0.1 0.3 0.1 0.0 0.9 0.1 0.0 0.2 3.5 0.0 0.1 0.0 0.0 0.1 0.1 1.8 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.2 0.1 0.5 0.2 0.1 0.2 1.3 0.2 0.2 0.0 0.1 0.2 0.3 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.3 0.6 0.2 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.1 0.3 0.5 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 2.0 2.8 2.5 1.9 2.9 1.6 2.5 1.9 0.9 3.5 1.8 6.9 0.0 15.9 13.4 4.3 0.0 0.2 0.0 5.2 1.2 6.6 6.1 0.7 0.0 3.7 5.5 10.4 0.2 7.1 0.0 0.0 2.6 0.0 2.7 8.3 2.6 0.0 1.7 20.5 2.3 0.3 3.3 0.5 3.6 1.3 7.7 0.4 0.2 0.2 1.7 24.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 8.4 0.6 0.2 0.0 12.5 16.8 1.1 0.0 0.0 5.0 0.3 0.2 2.4 2.2 3.3 0.0 0.9 3.2 0.0 0.1 1.5 0.0 0.3 3.8 4.2 0.0 0.3 KAT14 "ATAC2, CRP2BP, CSRP2BP, dJ717M23.1, PRO1194" ENSG00000149474 "Lysine acetyltransferase 14" Q9H8E8 20 18137228-18188387 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 17.5;Extravillous trophoblasts: 38.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 87.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068443 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA068443: AB_2685990" "unprognostic (4.02e-2)" "unprognostic (1.17e-1)" "unprognostic (8.60e-2)" "unprognostic (9.38e-2)" "unprognostic (3.98e-1)" "unprognostic (1.90e-2)" "unprognostic (3.37e-2)" "unprognostic (3.21e-1)" "unprognostic (4.04e-1)" "unprognostic (2.29e-1)" "unprognostic (7.15e-3)" "unprognostic (1.96e-2)" "prognostic favorable (4.64e-5)" "unprognostic (4.51e-1)" "unprognostic (4.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" 6.4 8.4 8.9 4.5 9.5 2.0 7.9 8.9 9.9 7.6 7.6 9.8 8.8 7.8 10.5 7.1 9.4 5.2 7.3 9.8 9.0 9.0 8.3 4.7 7.4 8.0 8.3 10.8 8.0 10.3 7.9 8.3 7.9 7.5 8.8 7.2 7.9 8.0 20.8 9.9 8.5 7.7 8.3 7.7 11.2 8.6 10.3 11.3 8.3 16.6 7.8 8.8 7.4 9.3 8.9 12.9 10.1 9.7 13.4 11.2 87.5 8.4 12.1 11.2 11.1 46.7 11.8 20.7 5.1 7.0 15.9 10.8 10.3 8.9 8.9 8.0 4.1 13.0 3.6 7.4 11.0 12.4 8.5 9.2 16.1 6.7 12.7 10.0 9.1 16.9 7.4 10.6 11.1 10.7 22.1 7.0 14.9 20.4 12.2 11.1 25.1 8.2 10.7 5.3 13.8 8.7 10.8 24.8 13.8 9.2 10.4 11.1 7.7 10.5 4.1 7.4 6.3 9.2 19.0 11.1 3.4 6.0 11.3 0.6 5.7 1.8 9.1 5.7 10.8 7.9 9.2 10.8 8.5 9.8 12.9 10.0 0.5 10.7 11.1 5.9 5.9 8.4 8.9 9.5 8.9 9.9 9.8 9.0 8.0 8.3 7.9 8.3 10.3 9.3 3.1 9.6 6.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 4.3 3.9 0.0 0.0 4.3 1.8 0.0 17.5 1.6 0.0 1.9 4.5 0.0 6.9 5.8 2.1 0.0 0.0 0.0 6.4 38.2 2.3 0.0 5.8 3.8 8.3 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.3 0.0 0.0 6.9 4.4 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 4.1 1.6 7.9 0.0 0.0 KAT2B "GCN5, GCN5L, P/CAF, PCAF" ENSG00000114166 "Lysine acetyltransferase 2B" Q92831 3 20040446-20154404 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 165.2;Oligodendrocyte precursor cells: 418.2;Oligodendrocytes: 175.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002470, CAB004526, HPA055839, HPA073897" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "CAB004526: AB_2128417, HPA002470: , HPA055839: AB_2682938, HPA073897: " "unprognostic (2.91e-2)" "unprognostic (6.85e-3)" "unprognostic (9.05e-2)" "unprognostic (2.25e-1)" "unprognostic (2.66e-2)" "unprognostic (3.01e-3)" "unprognostic (2.44e-1)" "unprognostic (3.83e-3)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-3)" "unprognostic (7.13e-2)" "unprognostic (7.03e-2)" "unprognostic (2.26e-2)" "unprognostic (1.59e-1)" "unprognostic (5.16e-2)" "unprognostic (4.63e-2)" 17.9 9.9 38.7 15.4 46.5 48.0 10.3 39.1 40.3 14.9 33.8 13.8 17.7 12.3 8.1 27.4 11.7 12.6 35.9 34.4 42.2 16.6 39.3 16.2 22.4 41.7 44.9 27.7 18.7 51.0 10.2 13.7 43.0 14.5 12.5 33.9 37.6 13.0 60.2 14.3 21.5 13.6 37.1 19.8 13.9 2.7 42.2 23.6 14.4 56.1 20.1 11.9 15.1 45.1 2.7 6.9 3.8 6.2 15.1 14.2 8.8 8.8 13.0 9.1 13.3 2.1 4.5 24.0 3.6 16.7 11.5 2.0 9.4 2.8 7.6 21.8 9.0 21.0 10.7 0.7 7.1 3.2 26.2 6.1 5.0 7.9 5.1 16.0 8.8 5.8 13.7 32.9 13.0 3.3 7.0 6.4 1.6 6.7 6.8 9.1 7.1 5.1 12.4 14.2 1.9 4.1 4.9 7.9 30.5 5.9 8.2 14.2 8.5 15.3 6.1 5.8 10.1 12.3 27.6 5.7 13.9 13.8 33.0 0.6 0.4 1.3 1.5 0.7 1.5 0.4 1.3 1.1 0.4 0.8 0.4 0.8 2.4 0.5 0.5 1.2 2.2 0.3 38.7 46.5 39.1 40.3 34.4 42.2 41.7 44.9 43.0 37.1 42.2 45.1 15.5 32.1 20.8 165.2 11.9 8.5 11.3 2.2 3.4 14.6 5.5 5.0 64.1 4.3 10.4 5.5 4.2 7.3 19.5 16.6 11.7 3.8 3.8 6.4 5.7 14.6 11.5 52.2 22.4 4.4 1.1 11.7 3.6 13.1 10.8 12.3 20.7 33.6 7.7 15.2 32.1 7.3 4.1 22.8 23.3 1.8 6.5 16.0 17.8 52.5 11.1 14.8 14.4 418.2 175.4 3.3 2.4 5.3 19.9 7.1 24.7 6.2 12.7 11.9 6.6 25.2 9.0 0.8 1.4 10.0 12.9 9.9 23.5 2.9 3.8 8.0 KAT8 "FLJ14040, hMOF, MOF, MYST1, ZC2HC8" ENSG00000103510 "Lysine acetyltransferase 8" Q9H7Z6 16 31114489-31131393 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 113.9;Late spermatids: 147.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 29.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066324 Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA066324: AB_2685658" "unprognostic (8.58e-2)" "unprognostic (9.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.12e-2)" "unprognostic (8.59e-2)" "unprognostic (1.06e-1)" "unprognostic (3.22e-1)" "prognostic favorable (6.34e-4)" "unprognostic (3.13e-2)" "unprognostic (3.05e-1)" "unprognostic (5.50e-2)" "unprognostic (9.77e-2)" "unprognostic (7.33e-2)" "unprognostic (2.97e-1)" "unprognostic (1.29e-1)" "unprognostic (5.00e-1)" "unprognostic (1.41e-1)" 28.8 30.9 40.4 17.8 41.6 32.9 31.3 50.6 50.4 40.8 38.2 36.9 16.6 39.2 46.5 21.1 41.7 14.7 42.0 41.5 41.6 28.4 29.0 31.3 24.6 42.0 41.3 60.7 31.8 37.4 31.0 20.4 41.3 32.0 17.3 27.5 34.7 23.7 49.8 33.8 30.2 25.5 40.0 39.7 28.2 32.8 41.6 39.6 35.5 49.8 23.3 30.9 31.0 43.1 18.1 27.4 33.5 10.7 38.5 28.9 34.3 16.0 29.6 24.7 26.8 13.6 38.1 42.3 24.5 19.6 22.8 22.5 53.6 26.4 24.1 35.8 35.0 18.7 21.5 43.3 34.5 30.5 31.9 27.9 51.4 18.5 52.4 33.2 23.6 44.1 49.5 33.7 13.1 51.4 47.4 57.2 38.0 43.1 15.9 75.1 28.1 49.5 20.1 10.7 35.2 35.9 9.4 25.9 14.1 20.7 28.6 49.6 14.7 11.0 22.2 12.1 11.6 32.4 34.8 24.2 16.0 40.7 16.3 8.0 7.4 29.9 3.0 4.1 3.7 3.6 3.6 4.1 6.6 2.9 4.6 3.3 28.4 3.2 8.3 2.7 2.4 3.4 40.4 41.6 50.6 50.4 41.5 41.6 42.0 41.3 41.3 40.0 41.6 43.1 26.2 19.2 18.2 16.0 30.4 20.8 41.9 18.1 34.7 19.0 21.5 26.2 16.8 21.5 21.0 9.2 14.6 30.5 20.9 17.8 21.5 21.9 113.9 17.5 18.2 21.8 24.6 29.5 16.4 26.6 21.7 29.4 17.9 18.0 27.3 33.9 23.2 12.4 29.1 32.0 18.6 21.2 18.3 30.1 25.4 147.5 53.7 28.1 24.9 12.2 32.6 41.0 15.5 11.1 13.2 15.0 25.8 54.2 16.5 35.2 25.1 17.5 11.8 26.9 26.3 32.8 30.6 27.5 26.2 20.6 15.6 45.4 24.6 24.5 22.9 23.2 KAZALD1 "FKSG28, FKSG40" ENSG00000107821 "Kazal type serine peptidase inhibitor domain 1" Q96I82 10 101061989-101068131 "Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 23.0;Gastric mucus-secreting cells: 44.4;Intestinal goblet cells: 53.5;Proximal enterocytes: 78.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 30.8;T-47d: 36.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011800 Uncertain "Secreted to extracellular matrix" NA NA 65000 "Cluster 64: Macrophages - Immune response" "Cluster 6: T47d - Mammary gland" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA011800: AB_1852082" "unprognostic (3.34e-1)" "unprognostic (8.86e-3)" "unprognostic (1.16e-2)" "unprognostic (4.43e-3)" "unprognostic (4.88e-2)" "unprognostic (1.35e-2)" "unprognostic (6.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (3.44e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.11e-1)" 2.9 0.6 0.3 0.6 0.2 0.3 2.8 0.3 0.4 7.1 0.1 1.9 2.8 2.0 1.3 0.6 2.1 0.6 8.1 0.5 0.2 2.0 0.5 1.2 0.7 0.4 0.3 0.5 0.9 0.8 3.6 0.8 0.4 5.2 1.6 0.4 6.9 2.2 4.1 1.7 3.2 1.5 0.2 18.0 6.6 1.9 0.4 1.0 2.5 3.1 0.3 3.6 2.9 0.2 3.3 1.6 1.8 30.8 1.8 7.4 2.0 5.2 5.6 1.0 1.0 6.2 2.0 0.2 2.8 4.6 0.5 0.7 1.9 0.1 0.3 3.1 0.8 0.4 6.5 6.7 0.5 0.4 2.3 1.1 0.4 0.1 0.9 0.4 0.0 0.9 0.7 3.2 0.9 5.3 0.1 1.9 0.5 7.2 11.7 12.4 9.1 0.4 0.6 1.6 0.3 1.2 0.5 0.8 1.7 0.7 36.7 0.5 0.1 0.7 2.1 0.5 1.2 0.9 2.6 2.5 1.3 3.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.4 0.5 0.2 0.4 0.3 0.4 0.2 0.4 0.2 8.3 0.0 1.5 0.7 0.3 2.0 0.9 1.6 0.6 1.5 2.5 3.0 3.4 1.5 1.6 0.0 2.1 0.3 0.3 23.0 1.9 0.5 0.1 4.1 1.3 5.1 2.4 2.7 0.1 2.1 0.6 16.9 44.4 7.2 0.0 0.2 3.6 0.3 0.8 0.0 0.1 53.5 4.1 4.8 1.9 0.1 9.9 0.9 1.8 0.0 0.0 0.8 0.0 0.0 0.1 1.5 12.8 0.4 0.2 5.0 78.1 0.4 0.7 2.2 0.0 10.4 6.1 3.9 1.4 0.7 2.8 0.5 0.6 0.2 8.1 0.4 KCNIP3 "CSEN, DREAM, KCHIP3" ENSG00000115041 "Potassium voltage-gated channel interacting protein 3" Q9Y2W7 2 95297327-95386077 "Predicted intracellular proteins, Transporters" "Apoptosis, Ion transport, Potassium transport, Transcription, Transcription regulation, Transport" "Ion channel, Potassium channel, Repressor, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 39.0;Leydig cells: 25.4;Oligodendrocyte precursor cells: 54.8;Peritubular cells: 42.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 13.8;BJ hTERT+: 18.0;hTERT-RPE1: 23.2;RPTEC TERT1: 35.2;U-138 MG: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066717, HPA069797" Enhanced Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA066717: , HPA069797: AB_2686199" "unprognostic (1.05e-2)" "unprognostic (5.76e-2)" "unprognostic (3.33e-3)" "prognostic unfavorable (1.58e-5)" "unprognostic (2.67e-1)" "unprognostic (6.73e-2)" "unprognostic (2.23e-1)" "unprognostic (2.96e-1)" "unprognostic (2.73e-1)" "unprognostic (7.42e-2)" "unprognostic (2.32e-1)" "unprognostic (4.09e-1)" "unprognostic (1.44e-3)" "unprognostic (8.90e-2)" "unprognostic (6.51e-2)" "unprognostic (7.33e-2)" "unprognostic (1.04e-1)" 6.7 1.5 21.8 0.8 20.0 0.0 5.4 15.2 31.2 10.7 12.2 9.8 1.2 10.6 3.6 2.4 10.1 1.5 6.0 22.1 16.8 8.4 2.0 2.4 0.4 15.4 17.2 10.1 2.4 27.0 6.4 5.3 15.2 9.3 0.9 0.5 5.6 14.7 1.5 6.0 3.7 5.1 15.3 2.6 5.5 12.2 18.0 24.4 19.7 1.8 0.5 9.0 10.6 19.3 13.8 0.0 0.8 6.1 5.3 4.2 0.0 6.3 18.0 10.1 9.3 0.0 0.0 0.0 0.6 8.3 5.5 0.2 4.0 1.1 4.3 0.0 1.4 0.0 1.8 0.0 2.2 0.0 0.0 2.9 3.6 2.2 10.0 23.2 0.0 1.0 0.0 0.0 0.8 8.0 0.1 0.0 0.1 0.0 3.7 0.0 0.0 0.0 35.2 0.0 0.7 0.2 0.3 0.3 6.8 0.0 0.3 0.1 0.3 16.3 3.8 0.0 4.9 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 20.0 15.2 31.2 22.1 16.8 15.4 17.2 15.2 15.3 18.0 19.3 0.4 0.0 1.1 13.4 0.5 0.4 0.8 0.0 1.2 8.1 1.0 1.0 1.6 0.0 0.0 1.8 0.0 0.0 0.0 0.2 7.9 0.2 0.6 0.3 3.7 1.0 4.2 0.0 39.0 0.0 0.1 3.5 0.0 0.3 0.0 7.5 0.0 0.5 0.1 0.0 5.1 0.1 0.0 0.0 0.4 1.3 25.4 0.1 7.2 1.9 0.6 0.5 0.0 54.8 3.0 0.2 0.0 42.9 0.0 0.5 1.0 1.5 0.0 0.0 0.0 8.3 3.7 0.1 0.9 0.2 0.9 0.0 0.0 1.5 0.3 0.1 KCNK7 K2p7.1 ENSG00000173338 "Potassium two pore domain channel subfamily K member 7" Q9Y2U2 11 65592836-65595996 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 90.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 103.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 2.1;naive B-cell: 2.2;neutrophil: 1.5" "Group enriched" "Detected in many" 16 "B-cells: 2.2;granulocytes: 2.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA077577 Approved "Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA077577: AB_2686845" "unprognostic (1.12e-2)" "unprognostic (1.21e-1)" "unprognostic (6.08e-2)" "unprognostic (5.71e-2)" "unprognostic (8.59e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-3)" "unprognostic (8.53e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-1)" "unprognostic (6.90e-2)" "unprognostic (4.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.65e-1)" "unprognostic (3.57e-1)" "unprognostic (1.16e-1)" "unprognostic (8.11e-2)" 2.0 0.7 2.7 0.2 2.9 5.4 2.9 3.4 5.7 4.6 1.7 2.1 0.4 1.4 0.1 18.0 2.3 0.3 1.6 2.7 2.4 0.7 0.9 1.7 0.3 2.8 2.8 1.8 0.4 0.0 1.3 0.4 3.0 1.4 0.0 0.7 2.5 0.3 2.6 90.0 1.2 0.2 2.7 2.0 1.2 1.1 2.7 0.4 0.6 0.5 1.0 1.7 9.5 3.4 0.3 1.6 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.1 1.0 0.4 0.4 0.1 0.2 2.2 0.0 0.0 0.0 0.5 1.1 0.5 0.9 0.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.8 0.6 1.3 0.4 1.0 0.5 0.4 0.6 0.6 0.6 0.9 0.0 0.2 0.6 0.1 6.8 1.5 0.3 0.4 0.7 0.0 0.4 1.1 0.0 0.3 1.1 1.0 0.1 0.9 0.7 0.2 0.5 0.6 0.6 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.2 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 2.7 2.9 3.4 5.7 2.7 2.4 2.8 2.8 3.0 2.7 2.7 3.4 1.1 0.0 0.5 0.3 0.8 19.1 0.4 0.7 0.6 2.1 0.7 1.8 0.2 0.0 0.7 0.0 0.0 0.1 1.6 1.0 0.0 0.1 0.7 0.7 0.3 1.2 1.2 0.0 0.9 0.0 0.1 0.4 0.0 1.7 0.0 0.2 0.7 0.3 0.5 0.0 0.9 0.4 0.0 1.3 4.0 1.8 0.6 0.7 3.6 0.0 0.4 0.1 0.0 1.0 1.8 0.1 4.8 0.0 0.0 0.3 0.3 0.1 1.1 1.1 6.6 0.4 0.8 0.1 1.3 16.3 103.7 0.0 0.6 0.1 0.8 1.3 KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43781257 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 130.8" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 231.1;Syncytiotrophoblasts: 763.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.7;WM-115: 258.6" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 17: WM-115 - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" 3.6 0.7 1.7 11.8 1.9 18.3 12.4 1.3 1.8 11.8 1.4 18.5 6.4 1.6 1.8 6.5 5.8 3.5 1.1 1.5 1.6 1.4 0.8 7.3 12.5 1.6 1.6 0.6 1.0 0.0 0.7 14.3 1.7 28.6 6.2 0.2 130.8 7.5 0.4 29.1 26.0 0.7 1.9 20.5 35.1 2.7 2.0 5.0 2.1 0.2 9.2 18.2 6.5 2.3 22.4 35.2 0.1 0.2 0.0 2.2 55.0 0.8 1.7 0.7 0.1 0.5 85.7 6.7 9.8 0.9 9.1 13.6 0.0 28.8 1.7 40.9 0.0 29.8 48.6 0.5 0.0 0.3 0.3 0.0 2.9 1.3 6.6 52.7 0.0 0.3 2.6 2.3 0.3 18.7 4.8 17.9 0.2 43.1 42.4 16.8 0.7 21.0 13.0 55.3 0.2 0.1 62.2 70.1 32.6 1.7 0.3 15.1 1.5 12.6 75.9 0.4 45.3 0.1 1.4 2.6 45.9 5.1 258.6 5.8 21.1 0.0 0.5 35.3 0.7 37.3 10.4 5.0 30.7 21.6 6.6 6.3 1.1 0.0 20.1 0.9 15.2 11.2 1.7 1.9 1.3 1.8 1.5 1.6 1.6 1.6 1.7 1.9 2.0 2.3 1.6 0.0 1.9 1.3 24.7 2.8 45.7 79.5 3.4 0.2 69.7 56.6 0.4 7.2 18.4 1.8 4.2 231.1 4.1 22.0 0.0 5.9 1.2 1.7 0.2 4.0 0.0 32.4 1.5 3.9 14.1 2.3 57.1 4.2 0.0 0.0 0.4 0.0 43.7 0.0 1.1 8.9 2.0 7.2 78.2 0.3 0.0 23.3 21.4 1.0 2.5 0.1 1.0 0.5 0.8 63.8 22.3 0.0 22.4 63.5 1.0 0.1 2.2 0.5 0.0 0.3 1.4 0.4 1.4 2.1 2.3 763.3 9.5 0.0 51.1 65.6 KCNU1 "KCa5.1, Kcnma3, KCNMC1, Slo3" ENSG00000215262 "Potassium calcium-activated channel subfamily U member 1" A8MYU2 8 36784324-36936125 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 7.5" "Group enriched" "Detected in some" 15 "Early spermatids: 61.1;Late spermatids: 24.3" "Cancer enhanced" "Detected in single" "liver cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HDLM-2: 7.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA063317 Uncertain "Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA063317: " "unprognostic (2.42e-3)" "unprognostic (4.26e-2)" "unprognostic (2.07e-1)" "unprognostic (4.76e-3)" "unprognostic (7.57e-2)" "unprognostic (1.12e-1)" "unprognostic (1.11e-1)" "unprognostic (2.71e-1)" "unprognostic (1.98e-1)" "unprognostic (7.73e-2)" "unprognostic (1.24e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 7.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 24.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 KCP "CRIM2, FLJ33365, NET67" ENSG00000135253 "Kielin cysteine rich BMP regulator" Q6ZWJ8 7 128862042-128910719 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "kidney: 17.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 53.3;Early spermatids: 23.1;Late spermatids: 28.7;Proximal enterocytes: 55.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.5" "Region enriched" "Detected in single" 5 "cerebellum: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.3;HMC-1: 5.1;U-87 MG: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "unprognostic (6.12e-2)" "unprognostic (5.49e-2)" "unprognostic (1.45e-3)" "unprognostic (6.33e-3)" "unprognostic (2.14e-1)" "unprognostic (5.24e-3)" "unprognostic (2.01e-3)" "unprognostic (3.25e-3)" "unprognostic (9.59e-2)" "unprognostic (1.52e-1)" "unprognostic (2.20e-3)" "unprognostic (6.46e-2)" "unprognostic (1.93e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (4.84e-2)" "unprognostic (7.64e-3)" 1.5 0.1 0.0 0.2 0.0 0.0 0.3 1.8 0.1 0.9 0.0 0.1 0.4 0.0 0.0 1.6 0.5 1.0 0.1 0.0 0.0 17.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.4 2.2 0.1 0.2 1.0 0.0 0.0 0.2 0.6 0.2 0.3 0.0 0.5 0.2 0.0 0.2 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 9.3 0.2 1.3 0.0 0.1 0.6 0.0 0.0 0.0 1.3 0.0 0.6 0.0 0.8 0.1 0.0 5.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.9 12.8 3.4 0.3 1.9 0.0 0.9 0.0 1.2 3.0 0.6 0.9 0.8 0.0 3.7 53.3 2.1 0.2 0.9 2.1 0.0 0.3 23.1 2.1 1.3 0.8 2.4 0.0 0.4 0.2 4.1 2.0 3.1 2.9 2.5 0.2 2.2 0.3 1.0 3.3 2.6 5.3 0.0 1.3 0.0 28.7 1.2 3.1 0.0 0.0 0.1 0.4 2.1 0.0 0.2 4.3 1.9 0.4 1.9 0.3 55.9 6.4 0.0 1.3 0.0 7.3 1.7 6.3 3.7 2.1 0.0 1.4 2.2 0.5 9.2 4.1 KCTD9 "BTBD27, FLJ20038" ENSG00000104756 "Potassium channel tetramerization domain containing 9" Q7L273 8 25427847-25458476 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042468, HPA047902" Supported "Nucleoplasm,Intermediate filaments,Cytosol" No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Intermediate filaments, Cytosol" "HPA042468: , HPA047902: AB_2680205" "unprognostic (4.18e-2)" "unprognostic (3.90e-2)" "prognostic favorable (7.88e-4)" "unprognostic (7.04e-2)" "unprognostic (7.41e-2)" "unprognostic (1.05e-2)" "unprognostic (2.20e-2)" "unprognostic (6.01e-2)" "unprognostic (4.33e-1)" "unprognostic (2.43e-2)" "unprognostic (4.49e-3)" "unprognostic (2.30e-1)" "unprognostic (1.48e-1)" "unprognostic (6.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.31e-2)" "unprognostic (4.97e-3)" 18.4 8.2 4.9 11.5 5.8 21.5 22.3 7.9 6.5 15.4 8.6 21.1 19.6 11.3 13.0 23.8 14.6 13.3 38.3 5.5 5.9 12.8 10.8 13.4 12.2 9.1 7.7 14.2 11.2 11.0 9.8 12.0 10.0 17.4 22.6 12.9 17.5 15.6 29.5 19.0 17.7 14.5 7.8 9.4 12.8 12.9 6.9 14.7 13.7 36.7 14.4 15.6 18.7 6.9 46.4 32.4 34.5 11.9 44.0 58.0 28.2 68.6 61.4 44.1 44.5 23.4 33.2 30.1 28.6 69.0 62.3 30.3 30.6 32.3 52.9 15.4 18.2 35.3 30.2 21.7 53.2 12.3 25.1 44.8 38.5 40.2 33.2 26.9 37.8 29.6 37.8 23.0 50.7 12.4 48.2 21.6 16.8 35.8 17.0 18.6 39.8 11.2 45.0 26.1 8.8 11.4 52.7 23.1 35.8 30.8 17.8 14.2 42.2 48.5 28.2 94.1 37.6 6.6 12.9 39.1 33.9 21.8 35.8 0.7 0.5 1.2 1.0 0.7 1.0 0.6 1.0 1.0 0.3 0.3 0.6 0.9 0.5 0.2 0.9 1.0 1.1 0.4 4.9 5.8 7.9 6.5 5.5 5.9 9.1 7.7 10.0 7.8 6.9 6.9 19.5 32.1 18.5 18.6 8.9 74.4 36.4 26.0 31.9 13.7 20.4 12.7 61.1 5.7 24.2 27.6 25.0 9.4 23.3 53.8 13.7 17.6 6.5 12.8 12.7 16.8 10.2 20.2 14.3 27.2 17.6 32.5 8.2 17.9 20.3 10.9 12.5 9.0 9.3 3.3 12.9 16.0 18.3 9.3 18.5 5.2 30.7 12.9 30.2 36.5 8.5 8.1 18.6 17.1 13.6 36.6 21.6 55.7 17.1 52.6 25.8 10.4 17.4 19.6 6.6 21.6 26.2 35.6 26.4 41.6 54.7 11.2 19.8 14.4 17.7 46.0 KDM1A "AOF2, BHC110, KDM1, KIAA0601, LSD1" ENSG00000004487 "Lysine demethylase 1A" O60341 1 23019443-23083689 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005884, HPA053660" Supported Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 7700 "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Cytosol "CAB005884: AB_443964, HPA053660: AB_2682220" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "prognostic favorable (6.31e-4)" "unprognostic (1.50e-1)" "unprognostic (6.83e-2)" "unprognostic (3.95e-2)" "prognostic unfavorable (4.47e-12)" "unprognostic (1.80e-2)" "unprognostic (1.99e-2)" "unprognostic (9.41e-2)" "unprognostic (3.34e-3)" "unprognostic (2.13e-1)" "unprognostic (2.61e-1)" "unprognostic (1.41e-1)" "unprognostic (3.73e-2)" "unprognostic (7.74e-2)" "unprognostic (1.39e-1)" 25.7 30.8 24.7 23.5 25.8 48.1 30.6 26.5 27.0 33.1 20.4 31.6 26.4 36.0 46.9 35.0 34.2 25.3 26.1 25.3 28.2 24.7 22.3 24.5 34.7 19.8 22.0 41.4 36.2 51.2 41.5 31.5 21.0 32.2 33.8 30.9 36.6 29.4 47.3 38.2 29.2 30.1 21.2 25.2 29.3 86.9 27.4 55.8 28.5 34.0 37.2 34.6 31.5 21.8 128.1 64.7 180.8 160.7 47.0 59.5 128.4 53.1 66.4 106.0 93.7 61.2 120.5 94.5 74.1 87.6 53.7 139.5 169.5 101.0 133.3 86.3 102.7 133.0 105.7 150.6 59.6 103.7 56.0 55.6 71.4 112.8 78.9 93.0 134.1 171.7 148.0 43.4 76.3 75.9 227.3 79.2 118.3 70.8 93.0 214.7 119.1 64.1 89.0 81.0 225.0 169.9 239.4 62.4 80.2 126.1 62.7 76.2 109.5 47.0 78.4 88.1 73.6 55.6 47.1 109.3 49.2 120.4 68.3 2.0 2.5 4.3 4.1 4.3 3.4 7.4 3.5 3.8 3.1 2.1 4.5 4.9 0.2 3.0 5.5 6.8 4.4 1.4 24.7 25.8 26.5 27.0 25.3 28.2 19.8 22.0 21.0 21.2 27.4 21.8 18.7 19.2 29.1 33.6 15.9 18.6 27.1 19.9 33.0 27.5 20.4 22.1 24.4 11.5 19.0 23.9 27.1 31.6 18.1 15.7 17.6 35.4 43.5 45.9 49.3 20.4 22.8 29.7 51.1 24.7 57.2 24.8 23.4 44.4 12.0 49.5 16.8 17.2 15.0 15.2 51.2 24.9 22.4 15.1 19.7 20.3 21.5 20.2 12.4 30.0 28.1 19.3 12.3 50.3 30.4 28.1 13.5 23.0 28.9 26.3 17.2 15.7 29.5 19.8 0.0 22.2 25.0 131.8 67.1 36.1 12.8 16.6 15.4 34.3 27.6 20.5 KDM3B "C5orf7, JMJD1B, KIAA1082, NET22" ENSG00000120733 "Lysine demethylase 3B" Q7LBC6 5 138352685-138437028 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016610, HPA057202" Supported Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 12: NES - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA016610: AB_1852004, HPA057202: AB_2683367" "unprognostic (1.21e-1)" "unprognostic (1.42e-1)" "unprognostic (1.63e-3)" "unprognostic (1.34e-1)" "unprognostic (6.72e-2)" "unprognostic (1.72e-1)" "unprognostic (5.21e-2)" "unprognostic (1.68e-1)" "unprognostic (2.64e-1)" "unprognostic (4.68e-2)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "prognostic favorable (6.67e-4)" "unprognostic (1.73e-1)" "unprognostic (3.05e-1)" "unprognostic (1.43e-1)" "unprognostic (7.60e-2)" 21.7 19.4 22.6 16.9 23.0 25.4 25.3 22.2 22.8 22.7 21.1 23.9 18.6 23.0 28.3 21.2 24.2 14.2 20.0 21.3 20.7 21.4 14.5 19.3 23.0 23.4 22.7 30.8 20.3 34.2 16.5 20.5 21.5 21.8 24.0 36.3 22.2 25.9 41.5 28.1 23.4 20.8 21.9 26.0 21.6 19.4 23.9 35.9 23.2 27.1 29.4 24.8 19.9 21.8 24.3 32.4 65.0 58.7 27.2 23.3 47.0 15.6 27.1 30.0 33.5 35.7 27.2 46.3 27.9 30.3 41.0 24.3 53.2 37.8 32.6 30.3 29.3 39.2 28.6 27.1 25.4 32.2 43.3 26.9 39.0 22.1 26.7 23.2 34.6 29.3 31.8 26.1 34.3 30.3 46.4 41.0 31.0 34.1 13.7 53.1 48.5 30.9 40.4 31.6 32.7 35.9 27.0 28.0 25.7 93.2 27.3 43.5 31.9 17.9 17.4 19.3 28.8 32.8 16.7 40.2 12.5 45.6 25.6 0.2 2.9 4.2 2.3 2.2 3.2 2.3 2.7 3.0 2.5 2.0 2.5 2.3 5.5 4.2 2.3 3.0 1.7 1.3 22.6 23.0 22.2 22.8 21.3 20.7 23.4 22.7 21.5 21.9 23.9 21.8 22.8 16.0 15.7 43.1 22.1 15.9 13.7 15.1 20.5 21.3 29.1 29.5 33.2 17.2 17.0 22.0 29.2 13.4 24.0 26.8 0.0 16.0 6.1 22.8 19.9 18.9 21.0 25.4 40.9 16.8 10.7 18.5 17.9 24.2 13.3 26.3 18.2 23.0 17.6 23.5 39.1 26.4 18.3 39.2 18.3 2.8 21.1 27.9 16.0 50.6 27.0 17.3 16.5 41.7 56.9 19.9 28.0 23.0 16.2 21.2 20.9 16.1 25.6 31.9 26.3 21.8 18.7 13.0 15.5 26.2 21.6 10.9 19.1 17.1 24.6 21.0 KDM6A UTX ENSG00000147050 "Lysine demethylase 6A" O15550 X 44873188-45112779 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 116.2;Oligodendrocyte precursor cells: 118.1;Oligodendrocytes: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000568, HPA001165, HPA002111" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.45e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.65e-2)" "unprognostic (2.58e-3)" "unprognostic (8.22e-3)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (2.24e-2)" "unprognostic (5.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.16e-2)" 9.6 8.0 6.7 4.5 7.6 19.4 10.6 7.2 10.6 15.7 6.5 9.1 6.2 14.0 5.1 11.1 14.0 3.4 6.6 6.8 6.9 6.8 10.4 10.8 8.0 7.3 6.8 17.2 10.8 6.4 8.6 3.9 7.3 7.7 4.1 3.8 10.5 3.1 10.4 18.4 13.0 4.1 7.1 14.1 12.5 12.2 7.0 12.9 9.4 6.1 5.3 9.8 15.2 9.9 7.3 5.8 7.0 9.3 5.0 6.8 15.7 4.9 4.2 4.0 4.1 10.4 5.2 4.6 3.2 3.5 10.1 13.9 6.5 5.4 3.9 7.6 10.8 2.4 4.5 5.2 3.7 2.6 13.2 2.6 6.4 8.2 6.6 5.1 4.2 5.3 6.4 10.1 2.4 6.0 6.9 13.6 6.8 4.2 7.4 6.4 7.1 1.4 3.8 9.2 6.2 4.4 18.2 6.8 10.7 14.1 8.5 0.0 3.0 5.4 5.2 5.2 3.6 5.5 8.8 5.6 4.0 3.3 3.3 7.3 1.7 1.5 1.9 3.5 2.1 1.9 2.5 2.8 3.1 1.2 2.5 2.4 2.8 2.8 3.0 1.7 2.2 2.0 6.7 7.6 7.2 10.6 6.8 6.9 7.3 6.8 7.3 7.1 7.0 9.9 23.2 6.4 10.6 92.1 26.0 26.1 14.3 9.4 38.1 7.7 16.8 12.1 12.8 12.8 10.9 7.3 14.6 4.5 26.1 24.6 0.0 8.4 1.5 26.4 25.5 13.1 13.1 16.8 88.3 7.5 7.9 14.2 23.0 39.7 2.5 27.3 6.4 17.6 7.0 25.2 74.0 14.0 6.1 9.1 13.8 2.0 6.5 19.9 10.6 116.2 12.6 6.8 6.2 118.1 264.6 9.1 17.4 7.2 31.4 14.2 22.6 3.7 8.9 9.7 6.6 20.9 17.0 14.1 12.5 29.3 26.3 10.9 27.4 10.6 13.1 17.1 KDM7A "JHDM1D, KIAA1718" ENSG00000006459 "Lysine demethylase 7A" Q6ZMT4 7 140084746-140176983 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 96.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012114 Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Nucleoli "HPA012114: AB_1852429" "unprognostic (1.55e-1)" "unprognostic (1.44e-1)" "unprognostic (2.54e-1)" "unprognostic (4.08e-3)" "unprognostic (3.52e-1)" "unprognostic (1.69e-2)" "unprognostic (4.00e-1)" "unprognostic (3.44e-2)" "unprognostic (2.56e-1)" "unprognostic (3.84e-2)" "unprognostic (9.74e-2)" "unprognostic (1.29e-1)" "unprognostic (9.55e-2)" "unprognostic (3.42e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-1)" "unprognostic (1.18e-1)" 6.6 2.1 2.1 6.9 1.6 16.4 4.7 3.8 3.9 9.5 1.5 8.4 8.2 6.6 1.4 7.0 2.9 4.5 4.1 2.7 1.6 3.6 6.7 4.8 7.0 2.5 2.5 2.1 4.5 4.1 1.3 9.1 2.8 3.3 9.3 5.8 5.1 2.1 12.6 7.5 8.3 4.4 2.4 5.6 9.3 7.7 3.7 6.7 2.8 13.2 8.0 5.7 3.7 3.0 0.8 0.4 2.7 2.8 2.4 2.3 5.4 1.2 1.7 0.4 0.5 0.2 0.4 1.9 1.9 1.3 1.4 1.0 3.7 2.3 0.8 10.8 2.3 0.1 0.4 5.1 2.5 1.8 1.9 2.4 5.1 1.4 8.0 1.3 2.6 5.0 6.1 8.2 0.5 0.8 3.6 3.1 4.3 6.3 1.5 3.8 0.2 4.0 0.9 1.2 4.7 5.8 2.8 6.5 2.7 4.3 8.8 0.7 4.6 0.5 1.0 1.7 0.8 2.9 0.4 6.2 1.5 5.0 1.0 0.6 0.8 0.3 0.3 0.4 0.3 0.5 0.5 0.5 1.1 1.1 0.5 0.3 2.2 0.6 0.2 0.4 0.4 0.3 2.1 1.6 3.8 3.9 2.7 1.6 2.5 2.5 2.8 2.4 3.7 3.0 34.4 16.0 25.5 25.5 30.6 49.8 44.8 17.7 8.0 11.8 11.1 7.4 14.6 8.6 30.1 16.5 27.1 12.3 17.8 36.7 1.9 7.2 5.2 17.0 18.2 23.8 52.7 32.4 35.3 9.4 2.8 20.0 30.5 28.7 8.2 12.2 18.5 18.5 10.7 6.7 34.8 38.0 12.2 31.4 86.7 4.9 7.8 35.4 3.6 96.5 34.7 4.3 10.3 35.7 36.0 12.2 28.7 4.1 11.8 35.3 26.9 3.3 33.3 9.2 6.6 14.9 17.8 31.2 14.3 12.3 46.5 37.9 18.5 3.4 27.2 50.0 KEL "CD238, ECE3" ENSG00000197993 "Kell metallo-endopeptidase (Kell blood group)" P23276 7 142941114-142962363 "Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 56.3;testis: 32.3" "Cell type enhanced" "Detected in some" "Erythroid cells: 79.7;Oligodendrocytes: 30.1;Squamous epithelial cells: 16.8" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "HEL: 31.7;K-562: 26.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA064442 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA064442: " "unprognostic (5.78e-3)" "unprognostic (1.08e-5)" "unprognostic (5.29e-3)" "unprognostic (4.85e-3)" "unprognostic (9.68e-2)" "unprognostic (1.96e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "unprognostic (5.18e-2)" "unprognostic (1.08e-2)" "unprognostic (3.71e-2)" "unprognostic (3.57e-2)" "unprognostic (2.29e-3)" "unprognostic (9.24e-2)" "unprognostic (7.05e-2)" "unprognostic (3.32e-2)" "unprognostic (3.25e-3)" 0.2 0.0 1.8 0.8 2.7 56.3 0.3 1.7 2.2 0.9 1.4 0.1 0.0 0.2 0.0 0.8 0.5 0.0 0.3 2.0 1.5 0.6 0.3 0.5 10.6 2.5 2.2 0.2 0.2 0.0 0.2 0.4 2.4 0.3 0.0 0.1 0.6 0.1 0.2 0.1 0.9 0.0 1.9 4.9 0.2 32.3 2.4 1.3 0.3 0.0 6.7 0.1 0.4 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 31.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.1 0.5 0.1 0.6 0.0 0.0 0.1 0.0 0.2 0.0 1.4 0.0 0.2 0.0 0.0 0.3 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.7 1.7 2.2 2.0 1.5 2.5 2.2 2.4 1.9 2.4 2.8 0.2 0.0 0.0 0.3 0.0 0.0 1.3 0.2 4.0 0.0 0.3 0.1 0.4 0.0 1.4 3.7 0.0 0.1 0.1 0.0 1.9 0.3 2.4 0.2 0.1 0.1 0.0 79.7 3.0 0.0 0.2 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 3.1 0.0 1.4 0.2 16.8 0.0 0.1 0.0 0.0 0.0 0.9 KERA "CNA2, SLRR2B" ENSG00000139330 Keratocan O60938 12 91050491-91058024 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Fibroblasts: 2.0" "Cancer enhanced" "Detected in some" "testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "amygdala: 4.1;basal ganglia: 5.6;cerebral cortex: 6.2;hippocampal formation: 5.6" HPA039321 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 50: Fibroblasts - ECM organization" "HPA039321: AB_10795248" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.47e-1)" "unprognostic (3.70e-1)" "unprognostic (4.76e-3)" "unprognostic (3.65e-1)" "unprognostic (6.08e-2)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-3)" "unprognostic (2.06e-2)" "unprognostic (2.53e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.1 0.1 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 KIAA0040 ENSG00000235750 KIAA0040 Q15053 1 175156986-175192999 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 100.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 105.8;Skeletal myocytes: 107.0;Syncytiotrophoblasts: 377.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 91.3;RPMI-8226: 65.5;U-698: 115.6" "HPA016895, HPA068812" Approved Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "HPA016895: AB_2669476, HPA068812: AB_2686041" "unprognostic (5.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "unprognostic (2.99e-2)" "unprognostic (1.01e-2)" "unprognostic (8.54e-3)" "unprognostic (2.91e-1)" "unprognostic (2.87e-2)" "unprognostic (3.83e-1)" "unprognostic (1.21e-1)" "unprognostic (2.66e-2)" "unprognostic (1.63e-1)" "unprognostic (2.53e-2)" "unprognostic (1.49e-1)" "unprognostic (2.57e-1)" "unprognostic (2.28e-2)" "unprognostic (3.05e-1)" 44.8 8.9 4.6 23.2 4.8 13.1 24.8 5.3 6.5 16.0 7.1 11.2 11.9 11.7 5.4 9.7 18.8 21.6 18.7 4.4 5.3 34.6 22.7 39.8 30.4 8.9 6.2 6.1 25.7 12.3 7.7 100.5 7.5 11.7 12.2 1.0 23.5 6.0 17.2 8.0 14.7 10.9 5.8 26.8 15.0 2.7 5.8 21.4 10.8 16.0 32.0 17.1 10.5 5.3 8.8 0.3 0.4 0.0 0.0 0.0 0.0 3.9 10.5 0.1 0.0 4.5 12.5 91.3 20.9 0.0 0.5 35.9 6.3 42.2 0.0 31.2 5.1 9.8 19.0 0.6 1.0 0.7 1.2 0.0 11.4 0.0 15.6 0.0 13.9 13.0 8.2 14.9 0.0 2.1 11.7 0.1 2.9 7.5 7.7 9.8 4.5 65.5 13.3 21.8 0.5 3.3 6.5 34.9 0.8 21.5 22.3 2.0 5.6 0.0 4.0 0.1 0.8 36.4 47.4 115.6 1.6 0.0 9.6 32.3 12.4 2.0 11.0 6.5 9.8 29.3 11.8 9.1 10.7 28.1 12.2 10.7 51.2 6.3 2.5 2.4 18.7 11.8 4.6 4.8 5.3 6.5 4.4 5.3 8.9 6.2 7.5 5.8 5.8 5.3 57.2 38.5 5.5 0.7 59.4 26.6 105.8 22.4 29.0 0.0 41.3 39.4 4.0 10.0 11.4 12.9 0.0 71.8 14.1 22.6 13.7 13.6 0.5 41.1 18.9 29.7 4.2 10.3 0.1 23.6 7.9 45.7 20.9 41.7 11.4 8.9 16.4 7.4 11.4 0.0 0.2 7.4 10.2 10.4 18.9 1.6 16.8 13.5 7.2 1.0 18.7 4.9 18.6 0.0 0.1 23.6 26.4 10.5 36.9 55.7 8.1 5.1 12.5 0.1 26.3 107.0 89.3 0.4 3.6 10.3 11.1 377.1 31.8 1.2 18.4 43.5 KIAA0100 "BCOX, BCOX1, CT101, DKFZp686M0843, FMP27, MGC111488" ENSG00000007202 KIAA0100 Q14667 17 28614446-28645454 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042781 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted to blood" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytosol" "HPA042781: AB_10797020" "unprognostic (1.91e-1)" "unprognostic (1.03e-2)" "unprognostic (3.47e-2)" "unprognostic (5.26e-3)" "unprognostic (2.43e-1)" "unprognostic (6.89e-2)" "prognostic unfavorable (3.47e-5)" "unprognostic (4.99e-2)" "unprognostic (3.04e-1)" "unprognostic (3.03e-3)" "unprognostic (2.40e-2)" "unprognostic (2.53e-1)" "unprognostic (4.24e-3)" "unprognostic (7.58e-2)" "unprognostic (5.84e-2)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 36.1 30.7 22.4 28.5 20.7 31.5 30.6 18.2 23.5 22.7 31.7 30.8 19.7 23.1 25.7 31.3 29.2 20.5 24.2 24.4 21.3 43.0 18.6 30.7 28.4 29.9 24.4 23.9 24.4 51.8 25.2 29.6 29.3 27.1 34.8 27.5 28.9 27.1 51.9 31.8 26.7 35.3 20.2 28.8 23.3 24.9 26.5 32.3 35.4 42.5 34.9 30.3 16.0 20.6 66.5 123.8 61.4 58.8 109.3 64.8 44.8 60.9 80.1 72.3 67.6 85.9 29.4 92.0 71.2 111.2 75.3 86.2 91.4 89.6 87.1 102.8 88.7 73.2 95.9 47.2 47.0 129.1 121.3 66.5 68.2 98.0 74.1 56.1 104.9 64.1 70.6 29.0 66.8 94.4 94.5 61.1 26.9 119.0 46.6 71.7 69.0 60.0 43.4 116.9 60.2 46.5 76.8 205.5 50.7 76.0 123.2 88.6 98.1 55.0 60.4 74.5 116.2 27.2 33.8 58.0 62.8 81.7 65.4 0.3 1.1 1.5 1.2 1.0 1.2 1.1 0.5 1.0 1.3 0.6 0.6 0.7 0.7 0.8 1.2 2.9 0.7 0.7 22.4 20.7 18.2 23.5 24.4 21.3 29.9 24.4 29.3 20.2 26.5 20.6 21.5 16.0 17.8 15.0 16.5 10.3 8.9 8.7 15.4 31.7 19.3 14.7 30.2 14.3 13.0 12.9 29.2 15.3 34.4 30.5 5.9 9.9 19.4 20.4 16.1 16.4 12.1 14.1 19.1 11.0 9.4 14.1 21.4 16.4 8.2 20.4 18.5 30.5 10.6 28.6 18.3 16.4 8.2 31.5 18.6 23.2 9.3 19.9 10.6 14.0 25.3 14.3 21.6 11.6 12.7 9.8 12.1 6.4 17.1 15.8 17.9 15.1 15.1 22.5 0.0 20.3 20.1 30.5 28.1 22.9 11.1 45.6 17.0 24.2 22.6 11.7 KIAA0319 NMIG ENSG00000137261 KIAA0319 Q5VV43 6 24544104-24646191 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.3;pituitary gland: 4.1" "Group enriched" "Detected in some" 8 "Astrocytes: 119.5;Early spermatids: 65.6;Excitatory neurons: 129.2;Inhibitory neurons: 72.7;Late spermatids: 96.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enhanced" "Detected in single" "granulocytes: 1.6" "Cell line enhanced" "Detected in some" "A-431: 2.0;A549: 2.0;GAMG: 2.1;HDLM-2: 2.4;HeLa: 1.9;SCLC-21H: 3.8;U-266/84: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015607, HPA076313" Enhanced Supported Approved Vesicles "Secreted in brain" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA015607: AB_1852299, HPA076313: AB_2732308" "unprognostic (1.64e-1)" "unprognostic (2.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "unprognostic (1.72e-2)" "unprognostic (4.65e-2)" "unprognostic (9.70e-2)" "unprognostic (2.21e-5)" "unprognostic (7.88e-4)" "unprognostic (9.53e-4)" "unprognostic (1.44e-6)" "unprognostic (1.20e-1)" "unprognostic (6.97e-2)" "unprognostic (3.13e-1)" "unprognostic (3.41e-2)" 0.0 0.4 10.0 0.2 10.3 0.0 0.1 4.3 10.4 0.1 0.6 0.4 0.0 0.0 0.0 0.0 1.6 0.2 0.0 9.2 5.8 0.0 0.0 0.6 0.0 7.2 7.4 0.0 1.4 0.1 4.1 0.0 7.6 0.4 0.4 1.2 0.2 0.0 0.0 0.7 0.2 0.1 2.7 0.2 0.8 1.1 12.3 0.0 0.0 0.0 0.1 0.0 0.0 4.8 2.0 2.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.6 0.9 0.0 2.1 0.8 0.3 0.0 0.0 2.4 1.0 0.0 1.9 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.3 0.0 0.1 3.8 0.2 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.4 0.3 3.2 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 10.0 10.3 4.3 10.4 9.2 5.8 7.2 7.4 7.6 2.7 12.3 4.8 0.1 3.2 0.5 119.5 0.6 0.0 0.0 0.5 0.0 3.6 0.1 0.1 1.4 0.0 1.5 0.0 0.0 0.0 0.0 1.4 0.0 0.4 65.6 2.6 0.1 0.0 10.2 0.0 129.2 0.0 0.0 0.3 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 72.7 0.8 0.0 0.0 0.0 96.8 0.6 0.2 0.0 5.6 0.6 0.3 0.0 5.0 3.1 0.3 0.1 0.7 0.0 0.2 0.0 0.1 10.9 0.9 0.0 0.1 0.0 1.2 1.5 0.0 0.0 0.7 0.1 0.1 0.3 0.3 KIAA0319L "AAVR, KIAA1837" ENSG00000142687 "KIAA0319 like" Q8IZA0 1 35433492-35557950 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 47.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072692 Supported Supported "Nucleoli,Golgi apparatus" NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" Nucleoli "HPA072692: AB_2686549" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (4.23e-3)" "unprognostic (1.75e-1)" "unprognostic (1.30e-2)" "unprognostic (1.87e-1)" "prognostic unfavorable (5.92e-5)" "unprognostic (3.41e-3)" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (2.05e-2)" "unprognostic (3.79e-1)" "prognostic favorable (1.27e-4)" "unprognostic (1.47e-1)" "unprognostic (1.26e-1)" "unprognostic (5.44e-2)" "unprognostic (1.84e-1)" 14.3 26.6 28.3 13.0 28.0 15.9 27.8 23.4 28.0 25.6 28.9 25.6 26.3 14.4 26.2 18.3 35.1 21.3 44.5 28.0 27.6 38.2 34.2 30.9 17.7 26.9 29.2 14.9 42.1 45.6 26.9 30.6 25.5 34.9 30.0 34.1 33.5 18.5 37.7 20.1 24.8 14.4 24.8 20.1 34.4 17.1 32.4 17.8 41.4 40.1 16.8 15.8 15.1 24.9 13.5 19.6 39.8 31.5 52.7 36.9 37.8 17.9 37.8 25.5 37.5 21.2 52.9 15.0 48.0 19.6 38.1 26.1 29.7 28.8 28.9 23.8 21.7 20.3 23.4 23.6 41.3 16.9 26.8 52.3 36.2 29.5 38.0 84.3 42.2 18.1 27.2 21.0 35.2 13.6 10.1 14.3 45.3 37.4 11.7 11.3 33.8 18.7 41.8 32.4 8.7 24.6 25.8 30.6 53.3 86.9 32.3 23.1 43.6 17.4 18.7 14.9 28.0 31.1 26.7 9.8 44.3 21.8 17.7 8.8 19.4 9.4 5.0 6.1 4.8 3.4 4.1 4.7 5.6 4.1 5.5 4.0 47.2 9.8 4.0 3.7 4.0 8.7 28.3 28.0 23.4 28.0 28.0 27.6 26.9 29.2 25.5 24.8 32.4 24.9 24.2 73.7 74.1 85.2 18.3 7.9 14.4 16.5 15.4 74.8 33.9 26.0 55.0 47.1 42.4 35.0 108.4 33.3 16.6 35.4 3.9 19.2 9.6 21.0 17.7 24.6 21.6 14.7 93.2 32.5 22.5 19.4 28.5 30.8 21.5 42.7 28.9 47.4 19.1 63.9 95.2 59.5 16.2 31.4 7.6 7.5 17.4 19.2 14.2 62.8 31.4 30.5 29.9 115.1 99.3 30.3 27.6 17.3 17.2 26.0 36.8 17.5 45.4 61.9 6.6 24.5 15.7 22.5 21.2 17.8 9.2 31.2 21.9 30.1 31.2 14.8 KIAA0930 "bK268H5.C22.1, C22orf9" ENSG00000100364 KIAA0930 Q6ICG6 22 45192244-45240894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 211.9" "Cell type enhanced" "Detected in many" "Astrocytes: 132.2;Excitatory neurons: 139.6;Oligodendrocytes: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 11.0;eosinophil: 8.6;intermediate monocyte: 13.9;myeloid DC: 12.1;non-classical monocyte: 17.3;plasmacytoid DC: 10.0" "Group enriched" "Detected in all" 5 "dendritic cells: 12.1;granulocytes: 8.6;monocytes: 17.3" "Cell line enhanced" "Detected in many" "THP-1: 327.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038091 Uncertain Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" Nucleoplasm "HPA038091: AB_10675627" "unprognostic (4.16e-2)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "prognostic favorable (9.22e-5)" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (6.90e-8)" "unprognostic (2.80e-1)" "unprognostic (2.03e-1)" "unprognostic (3.58e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-1)" "prognostic unfavorable (8.95e-7)" "unprognostic (6.89e-3)" "unprognostic (5.32e-2)" "unprognostic (5.58e-2)" "unprognostic (1.15e-1)" 33.9 58.3 195.7 27.7 209.3 24.7 25.9 163.3 211.9 46.0 130.3 29.4 14.6 24.0 40.4 34.5 18.2 16.0 18.1 184.1 189.1 23.8 48.4 24.8 29.0 182.8 192.6 13.6 20.1 18.5 19.2 12.0 179.8 29.1 11.2 3.5 26.7 24.7 33.8 64.0 21.4 15.2 170.4 38.7 18.6 26.2 193.6 20.4 18.4 13.1 22.3 44.0 35.6 210.3 49.6 31.5 19.1 38.3 64.1 30.2 19.2 26.9 26.8 28.2 24.1 29.5 26.5 33.2 39.2 42.8 22.5 54.5 29.5 118.6 10.7 35.6 46.4 0.1 42.0 34.3 25.7 89.4 19.7 17.1 59.2 27.3 45.3 21.5 26.8 23.9 11.7 53.1 17.4 56.9 40.0 82.8 18.9 35.8 26.5 48.1 12.9 110.7 42.6 29.7 15.9 28.4 42.5 57.6 75.5 36.8 28.1 327.8 36.5 29.0 50.6 39.7 15.7 44.9 32.9 32.1 34.0 133.7 30.3 0.8 11.0 8.6 2.3 13.9 1.6 2.3 0.9 2.6 12.1 1.8 0.9 1.6 2.5 1.9 17.3 10.0 2.0 3.7 195.7 209.3 163.3 211.9 184.1 189.1 182.8 192.6 179.8 170.4 193.6 210.3 11.4 6.4 8.8 132.2 9.9 52.8 18.6 22.7 6.8 7.3 13.9 13.5 11.5 12.8 11.8 18.4 6.2 2.0 24.9 16.2 0.0 18.6 2.9 11.6 9.3 9.7 10.7 23.1 139.6 20.7 6.5 32.7 4.6 19.5 2.5 3.8 17.5 23.3 67.5 5.0 56.7 10.0 14.2 71.1 50.0 10.8 10.8 59.8 44.4 24.4 68.5 6.5 13.4 16.1 152.9 18.0 13.7 14.7 11.2 25.6 15.7 13.8 9.3 5.9 0.0 10.2 10.9 7.5 4.4 15.2 57.3 2.7 9.3 5.3 12.8 23.1 KIAA1755 RP5-1054A22.3 ENSG00000149633 KIAA1755 Q5JYT7 20 38210503-38260772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 105.0" "Group enriched" "Detected in some" 4 "Astrocytes: 63.3;Microglial cells: 67.5;Oligodendrocytes: 135.6" "Cancer enhanced" "Detected in many" "melanoma: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 75.6;ASC diff: 11.3;ASC TERT1: 16.9;WM-115: 19.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051064 Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoli "Golgi apparatus, Vesicles" "HPA051064: AB_2681331" "unprognostic (3.98e-3)" "unprognostic (2.20e-2)" "unprognostic (3.79e-1)" "unprognostic (3.01e-3)" "unprognostic (1.77e-1)" "unprognostic (7.01e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (4.50e-2)" "unprognostic (2.70e-1)" "unprognostic (3.88e-2)" "unprognostic (1.69e-1)" "unprognostic (2.42e-8)" "unprognostic (1.41e-2)" "unprognostic (2.78e-2)" "unprognostic (1.25e-2)" "unprognostic (5.53e-3)" 5.6 2.1 18.4 6.0 87.7 0.5 3.4 39.2 42.2 13.1 0.0 9.0 2.4 14.6 6.4 5.1 8.7 16.2 11.4 29.0 64.1 4.1 1.2 2.5 5.0 59.2 62.3 13.6 0.9 0.1 2.2 0.1 54.7 6.6 4.2 0.5 5.8 7.3 0.6 1.4 4.2 14.7 18.3 2.7 3.6 2.6 75.3 8.3 2.0 1.7 4.7 5.2 4.8 105.0 3.0 0.3 75.6 0.1 11.3 16.9 0.0 7.6 4.3 0.0 0.0 0.3 2.2 0.0 0.3 2.4 2.5 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.3 0.0 2.2 1.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 2.0 0.1 0.0 0.0 0.4 0.0 1.1 0.4 1.4 0.0 0.0 0.0 0.2 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 87.7 39.2 42.2 29.0 64.1 59.2 62.3 54.7 18.3 75.3 105.0 0.1 0.0 0.0 63.3 0.0 0.3 0.0 0.0 0.0 0.0 0.8 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.1 2.5 0.2 0.0 0.0 0.8 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.4 1.1 0.1 0.0 0.5 0.0 0.0 0.0 0.5 1.9 3.7 0.2 1.8 67.5 0.0 0.0 0.0 19.6 135.6 0.6 0.0 7.5 0.0 0.0 0.0 4.1 0.0 0.0 0.0 1.1 1.2 0.3 0.3 0.2 0.3 0.0 0.0 0.4 0.0 0.0 KIF1A "ATSV, C2orf20, SPG30, UNC104" ENSG00000130294 "Kinesin family member 1A" Q12756 2 240713761-240824293 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 115.0;pancreas: 34.1;pituitary gland: 42.1;retina: 58.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 393.8;Cone photoreceptor cells: 419.1;Horizontal cells: 536.7;Muller glia cells: 116.4;Rod photoreceptor cells: 176.8" "Cancer enhanced" "Detected in many" "glioma: 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 62.5;HAP1: 146.0;SCLC-21H: 276.0;SH-SY5Y: 52.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005442 Approved "Centriolar satellite,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Centriolar satellite, Cytosol" "HPA005442: AB_1079210" "unprognostic (1.19e-1)" "unprognostic (2.17e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (4.97e-4)" "unprognostic (1.65e-1)" "unprognostic (4.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (3.09e-2)" "unprognostic (2.06e-2)" "unprognostic (2.60e-1)" "unprognostic (2.54e-1)" "unprognostic (3.83e-2)" "unprognostic (1.96e-1)" "unprognostic (1.74e-3)" "unprognostic (3.90e-2)" 0.2 12.4 54.0 1.1 55.6 0.0 0.1 22.4 113.6 0.1 0.0 2.2 0.7 0.3 0.8 0.0 0.2 0.0 13.7 71.8 25.0 0.2 0.4 0.3 0.0 115.0 47.4 0.7 34.1 0.4 42.1 0.0 107.7 5.4 0.5 58.4 0.2 0.2 0.2 1.0 0.8 0.3 10.2 0.4 2.6 11.2 53.9 0.4 0.9 0.1 0.0 0.1 0.6 99.6 0.0 0.2 1.8 62.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.1 0.0 3.5 0.4 1.4 0.6 146.0 0.0 0.0 8.4 10.5 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.3 0.0 2.5 0.3 0.0 8.8 0.0 0.0 0.0 0.6 1.2 0.0 0.0 276.0 52.0 0.0 0.8 0.0 0.4 0.4 0.0 2.0 0.0 1.3 0.4 0.0 0.2 0.1 0.0 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.0 55.6 22.4 113.6 71.8 25.0 115.0 47.4 107.7 10.2 53.9 99.6 0.0 0.0 0.0 50.9 0.0 0.9 0.1 0.0 0.0 393.8 0.1 0.3 16.8 0.0 0.0 0.0 419.1 0.0 0.0 0.1 0.0 0.5 2.2 1.1 0.2 1.2 34.2 0.0 57.6 25.1 0.0 2.9 4.1 5.0 0.0 1.5 0.0 0.4 0.1 536.7 72.4 0.8 8.2 0.0 0.4 4.1 0.9 0.1 17.8 9.4 0.0 116.4 0.0 18.1 50.3 14.6 0.0 0.4 0.0 10.4 0.0 0.3 0.0 176.8 0.0 0.0 1.0 46.2 20.5 0.0 0.0 0.0 0.0 3.8 0.1 0.5 KIR2DL4 "103AS, 15.212, CD158D" ENSG00000189013 "Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4" Q99706 19 54803535-54814517 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "lymphoid tissue: 4.5" "Group enriched" "Detected in some" 6 "dendritic cells: 23.6;NK-cells: 6.2;T-cells: 20.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 28 "NK-cell: 2.8" "Lineage enriched" "Detected in single" 28 "NK-cells: 2.8" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.98e-2)" "unprognostic (4.16e-2)" "unprognostic (1.84e-2)" "unprognostic (3.70e-4)" "unprognostic (2.23e-1)" "unprognostic (5.95e-4)" "unprognostic (1.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.92e-5)" "unprognostic (5.15e-2)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (4.53e-8)" "unprognostic (6.47e-2)" "unprognostic (2.66e-1)" "unprognostic (6.10e-4)" "unprognostic (3.59e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.8 0.0 0.0 23.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.2 2.5 0.0 0.7 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 6.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.0 0.1 0.0 KIRREL2 "DKFZp564A1164, FILTRIN, MGC15718, NEPH3, NLG1" ENSG00000126259 "Kirre like nephrin family adhesion molecule 2" Q6UWL6 19 35855861-35867136 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "pancreas: 70.0" "Cell type enriched" "Detected in some" 9 "Bipolar cells: 58.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 21.5;HMC-1: 33.0;JURKAT: 19.5;U-937: 7.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA071587, HPA074326" Enhanced Supported "Centriolar satellite" "Intracellular and membrane" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "Centriolar satellite" "HPA071587: AB_2732182, HPA074326: AB_2732251" "unprognostic (1.28e-2)" "unprognostic (1.80e-1)" "unprognostic (3.29e-2)" "unprognostic (3.16e-3)" "unprognostic (2.05e-3)" "unprognostic (2.29e-1)" "unprognostic (2.00e-1)" "unprognostic (1.72e-3)" "unprognostic (3.30e-2)" "unprognostic (5.56e-2)" "unprognostic (4.85e-2)" "unprognostic (2.62e-2)" "unprognostic (2.43e-6)" "unprognostic (1.72e-1)" "unprognostic (4.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.62e-2)" 0.5 0.0 0.5 0.2 1.4 0.1 0.0 0.3 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 1.1 0.0 0.0 0.8 0.4 0.4 0.0 70.0 0.0 0.9 0.1 0.4 0.0 0.1 11.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.6 0.5 0.6 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.7 1.1 0.0 0.0 0.0 1.6 0.1 0.0 0.1 0.0 1.1 0.7 0.0 0.1 0.0 3.6 0.1 2.9 0.0 0.1 21.5 0.1 0.0 0.0 0.3 0.0 0.0 33.0 0.2 0.0 0.0 0.0 0.0 0.0 19.5 0.2 0.3 0.0 0.2 0.6 0.1 0.2 0.1 0.0 5.5 0.0 0.0 0.0 0.0 4.1 1.3 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.8 1.3 0.3 0.0 0.0 0.0 0.4 0.0 7.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.4 0.3 1.0 0.8 0.1 0.4 0.4 0.4 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 1.8 0.1 0.2 0.1 0.0 0.0 0.4 6.0 0.1 0.1 0.0 1.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.7 5.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 KISS1 ENSG00000170498 "KiSS-1 metastasis suppressor" Q15726 1 204190341-204196491 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "placenta: 233.1" "Cell type enriched" "Detected in many" 26 "Syncytiotrophoblasts: 1336.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.2" "Region enriched" "Detected in some" 6 "hypothalamus: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "BJ: 145.5;U-2 OS: 59.4" "Not detected" "Not detected" "CAB017775, HPA035542" Enhanced Approved Vesicles "Secreted in female reproductive system" NA NA 860000 "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "CAB017775: , HPA035542: AB_2674677" "unprognostic (9.64e-2)" "unprognostic (1.78e-2)" "unprognostic (1.86e-2)" "unprognostic (1.18e-2)" "unprognostic (3.89e-1)" "unprognostic (6.87e-2)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (1.63e-1)" "unprognostic (8.98e-12)" "unprognostic (2.25e-1)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "prognostic favorable (6.29e-6)" 0.0 0.0 0.4 0.0 0.8 0.0 0.1 0.6 0.6 0.3 0.8 0.2 0.9 0.2 0.0 0.1 0.1 0.0 0.1 0.4 10.7 2.4 4.3 1.3 0.0 1.8 0.3 0.0 1.0 0.0 3.1 233.1 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.1 1.3 0.2 0.2 2.0 3.2 5.2 1.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.4 145.5 1.8 2.5 0.7 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.9 0.2 0.0 0.2 0.1 0.0 0.0 0.9 0.2 0.1 0.0 0.7 0.0 0.8 0.2 0.3 0.0 0.1 59.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.6 0.6 0.4 10.7 1.8 0.3 0.4 0.2 1.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 4.0 7.5 0.0 1.0 1.2 0.6 0.0 1.5 2.2 0.0 0.0 9.3 0.0 1.5 0.0 11.3 40.2 0.2 0.0 1.4 0.0 0.0 0.1 4.9 6.9 1.9 4.1 0.5 0.0 0.4 0.7 2.8 15.1 0.0 0.0 0.6 0.0 0.0 0.0 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.5 0.0 0.1 50.1 17.0 1.4 0.4 0.0 0.0 0.0 7.1 0.6 1.1 0.0 0.0 1336.6 0.1 0.1 2.1 14.3 KLF5 "BTEB2, CKLF, IKLF" ENSG00000102554 "Kruppel like factor 5" Q13887 13 73054976-73077541 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 242.0;skin 1: 234.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1105.5;Basal squamous epithelial cells: 757.5;Glandular and luminal cells: 678.2;Squamous epithelial cells: 1028.4;Suprabasal keratinocytes: 685.9;Urothelial cells: 1495.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 21 "basophil: 24.0" "Lineage enriched" "Detected in single" 140 "granulocytes: 24.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 111.8;HaCaT: 128.8;HBEC3-KT: 112.2;hTCEpi: 156.1;OE19: 246.3;RT4: 136.3;SiHa: 114.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 23.2" HPA040398 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Golgi apparatus, Vesicles" "HPA040398: AB_10673267" "unprognostic (7.90e-3)" "unprognostic (5.11e-2)" "unprognostic (2.03e-2)" "unprognostic (1.56e-1)" "unprognostic (4.69e-2)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (3.97e-2)" "unprognostic (5.82e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (4.43e-2)" "unprognostic (1.42e-3)" "unprognostic (3.56e-3)" "unprognostic (3.98e-1)" "unprognostic (5.09e-2)" "unprognostic (1.54e-2)" 6.5 5.9 4.2 18.0 9.1 63.5 36.2 0.6 3.3 49.9 2.7 161.2 130.4 6.7 6.6 242.0 37.5 55.9 3.3 2.6 3.4 8.5 4.7 29.6 2.0 0.8 3.4 4.5 11.9 0.5 10.9 18.8 0.7 23.1 145.4 0.4 79.8 14.4 19.2 234.9 146.2 6.6 0.5 1.5 82.2 12.0 4.1 12.0 25.7 7.8 53.6 111.5 122.2 1.0 22.3 31.1 0.2 0.4 1.1 1.5 34.1 12.9 29.8 5.6 6.9 28.5 111.8 0.4 68.9 11.4 2.3 128.8 39.0 112.2 8.9 0.9 11.0 0.4 61.9 2.8 7.8 10.5 1.9 8.1 156.1 1.7 61.1 5.7 0.1 3.8 1.6 2.2 25.5 7.9 2.1 0.8 1.4 246.3 43.3 2.0 28.3 2.5 87.3 136.3 2.9 1.3 114.5 18.3 8.5 13.9 2.5 2.5 0.3 7.8 23.1 0.2 5.4 3.7 1.9 3.8 10.8 2.1 9.5 24.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.1 4.2 9.1 0.6 3.3 2.6 3.4 0.8 3.4 0.7 0.5 4.1 1.0 7.8 163.5 123.3 0.7 5.2 518.9 1105.5 185.6 757.5 0.4 79.9 57.0 6.0 91.5 218.5 36.8 2.1 77.8 4.6 420.7 21.5 31.8 448.3 302.1 44.1 12.5 203.2 0.4 1.6 46.1 98.5 33.4 425.1 678.2 3.8 0.9 2.2 4.7 6.1 10.1 11.6 387.4 46.8 0.9 34.6 241.4 6.5 12.4 58.7 1.9 4.3 0.0 1.0 1.0 0.6 88.6 374.9 1.5 15.7 632.1 260.0 3.5 159.3 0.2 0.0 38.4 32.4 8.8 26.3 1028.4 685.9 58.0 17.4 0.5 505.4 1495.5 KLHDC7A FLJ38753 ENSG00000179023 "Kelch domain containing 7A" Q5VTJ3 1 18480930-18485974 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 8.4;kidney: 19.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 5.7;Collecting duct cells: 9.2;Endometrial ciliated cells: 4.4;Gastric mucus-secreting cells: 5.6;Hepatocytes: 7.6;Proximal tubular cells: 9.9;Respiratory ciliated cells: 5.0" "Cancer enhanced" "Detected in many" "renal cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.4;CAPAN-2: 10.4;EFO-21: 5.2;NTERA-2: 5.7;RPTEC TERT1: 11.5;RT4: 9.5;T-47d: 10.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA056616 Uncertain Approved "Nuclear speckles" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA056616: AB_2683193" "unprognostic (4.63e-1)" "unprognostic (3.74e-2)" "unprognostic (2.18e-1)" "unprognostic (5.25e-2)" "unprognostic (1.68e-3)" "unprognostic (2.02e-1)" "unprognostic (1.31e-2)" "unprognostic (1.80e-3)" "unprognostic (2.94e-2)" "unprognostic (1.91e-1)" "unprognostic (9.01e-2)" "unprognostic (2.79e-1)" "prognostic favorable (7.81e-9)" "unprognostic (4.64e-3)" "unprognostic (1.37e-1)" "unprognostic (3.44e-1)" "prognostic favorable (1.88e-4)" 0.5 0.0 0.0 0.0 0.0 0.0 4.5 0.7 0.1 2.3 8.4 0.6 0.4 0.0 0.2 1.3 0.8 1.0 0.0 0.5 0.0 19.5 4.7 1.0 0.0 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.0 0.4 0.7 0.0 1.7 1.1 0.0 0.0 0.3 0.0 0.0 0.0 4.9 0.2 0.1 0.0 1.6 0.0 0.0 3.2 0.3 0.0 0.2 5.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.1 10.4 0.0 5.2 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 1.1 0.0 0.2 0.0 0.0 11.5 9.5 2.8 0.0 0.0 0.8 0.0 1.0 10.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.3 0.5 0.0 0.0 1.7 0.4 1.2 5.7 2.2 9.2 0.0 0.1 0.0 0.3 1.9 2.0 0.4 4.4 0.3 0.1 0.0 0.0 0.0 2.2 0.1 0.1 5.6 3.0 0.0 0.1 0.0 7.6 0.1 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 1.1 0.0 9.9 5.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 KLHDC7B MGC16635 ENSG00000130487 "Kelch domain containing 7B" Q96G42 22 50545899-50551023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.2;parathyroid gland: 13.7" "Cell type enhanced" "Detected in some" "B-cells: 5.2;Collecting duct cells: 5.5;granulocytes: 5.7;Kupffer cells: 5.2;monocytes: 21.1;NK-cells: 10.3;T-cells: 5.7" "Group enriched" "Detected in many" 4 "cervical cancer: 42.3;head and neck cancer: 11.4;urothelial cancer: 40.7" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 4 "HMC-1: 97.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000518, HPA076540" Uncertain Approved "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "HPA000518: AB_1079213, HPA076540: " "prognostic favorable (1.30e-4)" "unprognostic (3.18e-2)" "unprognostic (2.74e-2)" "unprognostic (2.21e-1)" "unprognostic (3.96e-2)" "unprognostic (6.04e-3)" "unprognostic (3.91e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" "unprognostic (7.13e-2)" "unprognostic (3.33e-3)" "unprognostic (2.48e-1)" "unprognostic (2.09e-3)" "unprognostic (2.89e-1)" "unprognostic (4.69e-2)" "unprognostic (3.49e-1)" "unprognostic (1.02e-1)" 0.2 0.2 0.2 2.1 0.1 1.0 0.3 0.1 0.2 0.5 0.1 0.3 0.4 0.2 0.3 0.4 0.1 0.3 0.0 0.1 0.2 3.7 0.4 0.7 2.3 0.5 0.2 0.0 0.1 13.7 1.0 0.1 0.3 0.4 0.1 0.0 1.3 0.2 0.0 0.3 1.1 0.1 0.2 2.7 0.5 0.2 0.4 5.2 2.0 0.0 1.3 1.5 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.0 0.8 0.0 0.8 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.0 0.2 97.7 0.1 1.2 0.0 0.2 0.1 0.0 0.0 0.0 11.6 0.0 0.0 0.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.3 0.0 0.1 1.1 1.1 0.1 2.0 1.9 1.4 1.9 2.1 2.6 0.9 1.3 2.3 2.0 0.2 0.7 1.4 0.3 2.0 1.5 0.2 0.1 0.1 0.2 0.1 0.2 0.5 0.2 0.3 0.2 0.4 0.2 0.0 0.0 0.6 0.0 5.2 0.1 0.0 1.6 0.0 0.0 3.0 1.4 0.5 0.0 1.6 5.5 0.0 0.0 2.5 0.1 0.0 0.8 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.7 0.1 0.2 0.5 0.3 5.7 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 5.2 1.2 0.0 0.0 2.7 0.0 0.0 21.1 0.0 10.3 0.0 0.0 1.3 0.0 0.0 2.8 0.1 0.0 0.3 1.6 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 5.7 0.0 0.0 0.2 KLHL11 FLJ10572 ENSG00000178502 "Kelch like family member 11" Q9NVR0 17 41848518-41865423 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 108.3;Late spermatids: 41.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 24.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023021, HPA052403, HPA054269" Uncertain Approved "Nucleoplasm,Nuclear membrane" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear membrane" "HPA023021: AB_1852568, HPA052403: , HPA054269: AB_2682432" "unprognostic (9.90e-2)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.82e-1)" "unprognostic (2.07e-1)" "unprognostic (1.84e-2)" "unprognostic (1.32e-1)" "unprognostic (3.11e-2)" "unprognostic (1.50e-1)" "unprognostic (1.83e-2)" "unprognostic (3.25e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-3)" "unprognostic (4.05e-1)" "unprognostic (2.79e-1)" "unprognostic (3.09e-2)" "unprognostic (5.07e-2)" 2.0 2.5 7.5 2.0 6.9 9.1 3.6 8.7 8.2 2.2 1.6 2.0 1.7 2.8 4.0 1.8 2.5 1.6 2.0 9.7 7.6 2.6 2.5 2.3 2.8 6.8 6.3 3.9 3.0 4.6 0.8 2.0 7.4 2.9 1.8 7.1 2.2 2.7 4.3 3.2 1.7 1.8 5.1 2.8 2.2 9.7 7.5 2.7 4.5 1.9 2.8 1.6 0.8 7.0 3.3 5.6 3.9 10.3 5.3 2.8 6.8 3.1 2.9 3.3 3.1 5.2 2.5 10.7 3.4 3.8 3.0 9.3 10.1 4.4 6.0 4.1 4.5 3.8 8.2 7.1 4.9 4.7 4.1 3.4 4.0 4.4 8.3 3.4 3.4 5.3 3.4 9.1 4.3 4.2 7.1 4.9 3.4 2.9 1.8 6.1 9.5 7.7 3.7 5.7 9.8 4.8 5.4 24.9 4.2 3.8 10.9 3.8 5.3 5.1 6.9 4.9 6.2 5.6 5.1 7.9 5.4 4.9 4.8 0.2 0.5 0.3 0.5 0.7 0.8 0.6 0.6 0.6 0.5 0.8 0.7 0.6 0.2 0.4 0.4 0.3 0.4 0.4 7.5 6.9 8.7 8.2 9.7 7.6 6.8 6.3 7.4 5.1 7.5 7.0 1.2 0.0 0.5 6.8 4.5 0.5 1.4 0.2 14.8 3.8 0.9 1.8 0.2 0.0 1.5 0.0 4.2 0.4 3.6 0.3 0.0 0.4 108.3 1.6 3.4 1.5 0.0 3.0 16.6 0.2 0.4 3.0 10.7 1.9 0.0 1.1 0.0 0.0 0.3 8.4 18.0 0.7 0.0 0.0 1.0 41.8 0.3 1.5 1.8 4.7 0.9 1.8 1.0 11.1 13.9 0.5 0.1 0.0 5.8 0.9 0.9 0.2 0.0 3.6 6.6 2.2 3.2 5.5 2.1 5.5 0.3 0.4 4.6 0.9 0.6 0.9 KLK1 Klk6 ENSG00000167748 "Kallikrein 1" P06870 19 50819146-50823787 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 84 "pancreas: 9557.9;salivary gland: 5487.3" "Group enriched" "Detected in many" 7 "Exocrine glandular cells: 788.4;Intestinal goblet cells: 1317.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 50.9;renal cancer: 84.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "memory B-cell: 9.5;naive B-cell: 4.0" "Lineage enriched" "Detected in single" 13 "B-cells: 9.5" "Cell line enriched" "Detected in some" 4 "RPMI-8226: 43.8" HPA059690 Approved "Secreted to digestive system" NA NA 10000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA059690: " "unprognostic (1.51e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (1.92e-2)" "unprognostic (7.47e-3)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (8.06e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-2)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.23e-2)" 1.4 2.4 0.1 4.0 0.0 0.4 1.8 0.0 0.4 1.9 0.0 68.8 9.6 2.0 0.0 1.3 0.6 0.1 3.0 0.3 0.0 89.4 0.6 0.5 0.5 0.0 0.0 4.7 9557.9 0.4 0.2 1.1 0.0 2.7 53.0 0.0 5487.3 0.1 0.2 26.3 9.7 2.8 0.0 3.3 1.4 0.1 0.0 0.2 2.9 0.2 1.5 0.2 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.4 0.2 0.3 0.5 1.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 1.1 0.1 0.4 0.2 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.1 0.0 0.0 9.7 0.0 0.1 0.0 43.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 9.5 0.0 0.0 0.1 4.0 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 18.9 19.5 1.2 2.9 1.2 0.0 1.0 1.1 0.3 0.0 2.5 0.0 0.0 0.0 0.2 62.2 45.0 3.3 0.6 0.1 1.4 0.4 117.1 0.0 0.0 788.4 0.0 7.7 1.5 0.0 8.9 8.8 0.4 0.0 0.6 0.0 0.0 1317.5 14.2 1.6 5.3 0.3 6.2 1.5 5.4 0.0 6.2 0.0 0.0 0.0 0.0 125.8 134.4 0.0 10.9 9.8 57.1 0.3 0.3 0.0 0.0 0.0 1.1 0.3 0.9 1.7 54.0 0.0 2.1 2.5 148.5 3.8 KLK10 "NES1, PRSSL1" ENSG00000129451 "Kallikrein related peptidase 10" O43240 19 51012739-51020175 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Cell cycle" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 111.8;esophagus: 412.5;vagina: 190.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Basal respiratory cells: 61.4;Club cells: 113.9;Pancreatic endocrine cells: 74.8;Prostatic glandular cells: 68.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 97.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 67.2;HaCaT: 158.7;OE19: 68.1" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Not detected" "Not detected" "Secreted in other tissues" NA NA 2500000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "prognostic favorable (8.32e-4)" "unprognostic (6.06e-2)" "unprognostic (1.73e-1)" "unprognostic (4.26e-3)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.51e-2)" "unprognostic (2.10e-2)" "unprognostic (3.94e-1)" "unprognostic (3.38e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (2.71e-2)" "unprognostic (2.46e-6)" "unprognostic (9.34e-2)" "unprognostic (7.81e-2)" "unprognostic (2.66e-3)" "unprognostic (1.52e-2)" 8.6 0.6 0.7 0.2 0.4 0.6 6.2 1.2 0.4 111.8 1.0 1.5 0.3 1.7 0.2 412.5 8.6 3.5 1.3 0.3 1.4 0.6 0.3 8.7 0.0 2.6 1.7 19.7 0.6 0.2 1.5 0.2 2.8 7.2 0.6 0.3 55.2 0.5 0.2 65.7 2.6 0.6 0.7 0.2 1.8 6.0 1.0 0.3 0.6 0.1 18.8 0.6 190.6 0.4 21.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 67.2 0.0 6.6 0.0 0.1 158.7 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 68.1 0.6 0.0 0.0 0.0 6.9 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.1 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.4 1.2 0.4 0.3 1.4 2.6 1.7 2.8 0.7 1.0 0.4 0.3 32.1 2.6 0.0 0.0 7.5 15.6 61.4 9.1 1.0 12.3 14.0 0.7 8.6 113.9 0.0 0.0 0.0 0.2 1.2 0.0 7.5 0.3 2.1 1.0 1.7 0.0 0.0 0.1 15.4 0.0 6.0 1.1 8.0 0.0 0.1 1.1 0.0 0.1 0.0 0.6 0.0 22.4 0.0 0.6 0.6 11.5 0.5 0.0 0.0 0.6 0.3 0.0 0.0 0.5 74.8 0.0 6.0 0.0 68.6 0.0 0.0 15.8 0.5 0.0 0.4 2.6 1.0 1.6 28.0 4.3 0.0 0.5 0.5 0.0 29.6 KLK11 "PRSS20, TLSP" ENSG00000167757 "Kallikrein related peptidase 11" Q9UBX7 19 51022216-51028039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 324.2;skin 1: 239.8;vagina: 186.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 152.1;Club cells: 217.9;Late spermatids: 339.0;Prostatic glandular cells: 234.8;Squamous epithelial cells: 176.4;Suprabasal keratinocytes: 217.1;Urothelial cells: 186.1" "Cancer enhanced" "Detected in many" "prostate cancer: 53.3" "Region enhanced" "Detected in single" "hippocampal formation: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "EFO-21: 13.0;HaCaT: 41.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB026340 Approved "Secreted in other tissues" NA NA 1800000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB026340: " "unprognostic (4.23e-2)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.78e-4)" "unprognostic (2.08e-2)" "unprognostic (4.67e-1)" "unprognostic (5.32e-2)" "unprognostic (3.72e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.92e-2)" "unprognostic (4.16e-6)" "unprognostic (3.90e-2)" "unprognostic (2.73e-1)" "unprognostic (4.40e-2)" "unprognostic (2.53e-1)" 28.4 0.2 0.0 0.4 0.0 0.0 17.1 0.9 0.1 109.8 44.5 1.9 0.7 7.2 2.6 324.2 34.2 59.3 2.0 1.7 0.0 0.3 0.8 18.9 0.0 0.2 0.1 1.6 89.1 0.0 8.8 0.0 0.3 64.9 0.6 0.7 169.5 4.2 1.9 239.8 1.4 0.3 0.0 0.1 113.3 14.4 0.6 2.5 0.4 0.3 27.2 1.4 186.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.4 0.1 13.0 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.7 0.0 0.2 0.1 0.3 0.0 0.6 0.0 0.2 86.6 10.4 0.0 0.4 106.9 152.1 131.6 13.1 0.2 33.4 35.3 0.8 88.6 217.9 0.0 0.0 0.0 0.0 0.1 0.0 9.2 111.6 4.7 1.1 3.8 20.3 0.0 0.0 130.2 0.0 9.1 91.3 15.6 1.3 0.0 0.0 0.0 0.3 0.0 0.0 10.7 118.0 0.0 11.4 339.0 2.8 1.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 79.4 0.0 0.4 0.5 234.8 0.1 0.0 26.9 1.3 0.0 0.2 7.9 2.1 2.5 176.4 217.1 0.0 1.7 0.0 0.4 186.1 KLK12 KLK-L5 ENSG00000186474 "Kallikrein related peptidase 12" Q9UKR0 19 51029092-51035230 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "cervix: 108.5;esophagus: 208.6;salivary gland: 64.7;vagina: 99.4" "Cell type enhanced" "Detected in some" "Early spermatids: 30.7;Enteroendocrine cells: 40.3;Intestinal goblet cells: 24.9;Ionocytes: 14.2;Late spermatids: 34.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025473 Uncertain "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB025473: " "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (1.08e-3)" "unprognostic (1.15e-1)" "unprognostic (5.80e-3)" "unprognostic (4.99e-3)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.56e-1)" "prognostic favorable (8.01e-4)" "unprognostic (8.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 108.5 2.2 2.1 4.0 0.0 0.0 208.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.1 0.5 0.8 0.0 64.7 0.0 0.0 0.6 5.8 0.1 0.0 0.0 0.4 0.5 0.0 0.1 0.1 0.0 8.9 0.0 99.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.5 0.5 0.2 0.0 2.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 30.7 0.0 0.0 0.0 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 14.2 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.2 8.4 0.0 0.0 0.0 0.0 1.3 1.7 KLK13 KLK-L4 ENSG00000167759 "Kallikrein related peptidase 13" Q9UKR3 19 51055626-51065114 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 519.9" "Group enriched" "Detected in some" 4 "Late spermatids: 246.9;Squamous epithelial cells: 68.3" "Group enriched" "Detected in many" 4 "cervical cancer: 20.6;head and neck cancer: 42.3;melanoma: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HaCaT: 27.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA062136 Enhanced "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "HPA062136: AB_2684694" "unprognostic (1.99e-3)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (3.43e-1)" "unprognostic (2.99e-2)" "unprognostic (1.69e-1)" "unprognostic (6.76e-2)" "unprognostic (2.18e-2)" "unprognostic (8.30e-2)" "unprognostic (7.07e-6)" "unprognostic (7.33e-2)" "unprognostic (2.53e-1)" "unprognostic (6.38e-2)" "unprognostic (7.06e-2)" 0.2 0.2 0.1 0.2 0.1 0.0 1.6 0.1 0.2 96.3 0.9 0.6 1.6 0.5 0.4 519.9 0.5 1.1 0.2 0.1 0.1 0.1 0.2 0.7 0.0 0.2 0.5 0.2 4.4 0.4 0.3 0.0 0.1 0.6 0.1 0.0 74.9 0.0 0.1 10.8 0.8 0.3 0.1 0.1 1.4 4.3 0.1 0.2 0.3 0.0 63.5 0.2 122.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 27.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.5 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.6 1.1 4.0 0.0 0.9 1.9 0.4 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.1 0.1 0.3 1.8 0.0 0.0 1.3 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.3 246.9 0.3 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.2 1.0 0.7 68.3 1.3 0.0 0.4 0.4 0.0 2.1 KLK14 KLK-L6 ENSG00000129437 "Kallikrein related peptidase 14" Q9P0G3 19 51077495-51084245 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 9.7" "Cell type enhanced" "Detected in single" "Club cells: 2.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 10.7;HEK 293: 2.9;U-266/84: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" CAB026228 Uncertain "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "CAB026228: " "unprognostic (2.08e-1)" "unprognostic (1.22e-1)" "unprognostic (2.44e-2)" "unprognostic (2.60e-2)" "unprognostic (1.23e-1)" "unprognostic (6.12e-2)" "unprognostic (4.91e-2)" "unprognostic (5.79e-2)" "unprognostic (7.84e-2)" "unprognostic (1.38e-1)" "unprognostic (7.60e-2)" "unprognostic (8.87e-2)" "unprognostic (2.04e-8)" "unprognostic (1.93e-1)" "unprognostic (3.74e-3)" "unprognostic (1.94e-2)" "unprognostic (8.08e-2)" 0.5 0.3 2.1 0.2 2.2 0.1 1.6 2.3 3.3 4.2 1.9 0.4 1.3 0.5 0.6 0.9 0.7 0.3 0.8 2.2 1.7 0.5 0.3 0.4 0.3 2.1 1.9 1.1 0.7 0.0 0.6 0.0 2.2 0.8 0.3 0.6 0.8 0.5 0.3 9.7 0.7 0.1 1.6 0.6 0.6 0.9 2.0 0.3 0.4 0.1 0.5 0.6 3.9 2.3 1.4 0.5 0.1 0.6 0.4 0.4 0.6 0.1 0.0 0.0 0.1 1.2 1.4 0.6 0.4 0.2 0.3 10.7 0.1 0.2 0.0 0.3 2.9 0.2 0.9 0.0 0.1 0.2 0.2 0.2 0.3 0.4 0.4 0.1 0.1 0.4 0.2 0.3 0.0 0.9 0.2 0.5 0.6 1.2 1.1 0.1 0.1 0.6 0.0 0.6 0.1 0.0 0.2 1.0 0.3 0.2 0.4 0.0 0.0 0.1 0.4 0.6 0.2 2.6 5.5 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.2 2.3 3.3 2.2 1.7 2.1 1.9 2.2 1.6 2.0 2.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLK15 "ACO, HSRNASPH, prostinogen" ENSG00000174562 "Kallikrein related peptidase 15" Q9H2R5 19 50825289-50837213 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.2;salivary gland: 5.6" "Cell type enhanced" "Detected in some" "Early spermatids: 5.5;Intestinal goblet cells: 34.6;Late spermatids: 8.8;Spermatocytes: 15.0;Spermatogonia: 9.5" "Group enriched" "Detected in some" 4 "prostate cancer: 3.5;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPMI-8226: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA019802 Uncertain "Secreted to blood" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA019802: AB_1852601" "unprognostic (6.06e-2)" "unprognostic (2.85e-1)" "unprognostic (8.13e-2)" "unprognostic (2.90e-1)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (2.52e-1)" "unprognostic (2.72e-2)" 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 1.2 0.0 5.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.5 0.0 0.0 0.1 1.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 34.6 0.0 0.0 0.0 8.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 9.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 87 "prostate: 566.2" "Cell type enriched" "Detected in some" 40 "Prostatic glandular cells: 777.2" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 3.5;NB-4: 5.6" HPA000764 Supported "Secreted in male reproductive system" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" 0.7 1.1 3.2 1.2 2.3 6.4 0.5 5.2 4.3 0.2 2.2 0.4 1.5 0.6 1.1 0.5 0.3 0.2 0.3 2.6 2.2 0.4 0.8 0.5 1.0 2.2 3.1 0.4 0.0 0.8 0.0 0.2 2.9 566.2 0.3 1.7 1.9 0.4 1.0 0.8 1.0 0.1 0.6 0.7 0.5 3.0 2.4 0.0 1.9 0.0 0.2 0.2 0.0 6.3 0.9 0.6 0.3 0.7 0.0 0.4 3.5 0.2 0.1 0.1 0.1 0.3 0.4 1.0 0.1 0.0 0.3 0.9 0.1 0.0 0.1 0.9 0.6 0.0 0.7 0.0 0.0 0.1 1.7 0.2 0.1 0.1 0.2 0.2 0.0 0.6 0.7 0.9 0.2 1.0 0.6 5.6 0.5 0.9 0.0 0.4 0.0 1.6 0.0 1.1 0.5 0.5 0.1 0.7 0.6 0.1 0.5 0.2 0.4 0.6 1.0 2.6 0.9 0.8 1.8 0.4 1.0 0.6 0.7 0.4 0.6 0.5 0.3 0.3 0.2 0.3 0.2 0.3 0.1 0.6 0.2 0.4 1.7 0.4 0.2 0.5 0.1 0.2 3.2 2.3 5.2 4.3 2.6 2.2 2.2 3.1 2.9 0.6 2.4 6.3 0.0 0.0 0.6 0.0 0.2 0.3 10.2 0.0 0.0 0.0 16.1 2.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 5.2 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 777.2 0.0 0.1 0.0 0.0 0.0 0.0 1.8 19.3 7.2 0.0 0.9 0.0 0.6 1.7 0.0 12.0 KLK3 "APS, PSA" ENSG00000142515 "Kallikrein related peptidase 3" P07288 19 50854915-50860764 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 320 "prostate: 8011.8" "Cell type enriched" "Detected in some" 77 "Prostatic glandular cells: 3438.6" "Cancer enriched" "Detected in some" 3905 "prostate cancer: 4241.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 173 "BEWO: 31.7;NB-4: 27.8;RPMI-8226: 19.3;SH-SY5Y: 10.5;U-2197: 10.7" "CAB000070, HPA000764" Enhanced "Secreted in male reproductive system" NA NA 7000000 "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "CAB000070: , HPA000764: AB_1079700" "unprognostic (5.06e-3)" "unprognostic (5.60e-2)" "unprognostic (9.93e-2)" "unprognostic (3.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.13e-3)" "unprognostic (1.94e-1)" "unprognostic (4.64e-1)" "unprognostic (3.15e-1)" 4.3 7.6 0.0 5.6 0.0 0.0 9.0 0.0 0.0 0.5 0.0 2.6 4.8 1.6 14.4 0.2 4.0 0.0 0.5 0.0 0.0 1.4 1.5 1.2 1.7 0.0 0.0 0.3 0.9 0.6 0.2 0.3 0.0 8011.8 1.1 0.0 4.5 25.0 0.3 0.5 3.7 0.0 0.0 0.2 1.0 6.9 0.0 0.0 0.8 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 0.0 0.0 19.3 0.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 12.4 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.4 2.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.1 9.0 0.0 0.0 0.0 1.8 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 3438.6 0.1 0.1 0.0 0.0 0.0 0.0 6.9 0.1 0.0 0.0 0.0 0.0 4.2 0.2 0.4 44.6 KLK4 "EMSP, EMSP1, KLK-L1, PRSS17, PSTS" ENSG00000167749 "Kallikrein related peptidase 4" Q9Y5K2 19 50906352-50910738 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Hydrolase, Protease, Serine protease" "Amelogenesis imperfecta, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 32 "prostate: 286.4" "Cell type enriched" "Detected in some" 15 "Prostatic glandular cells: 106.1" "Cancer enriched" "Detected in many" 55 "prostate cancer: 463.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 6.4;HaCaT: 7.9;OE19: 7.3;SK-BR-3: 5.1" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 4.5" HPA051839 Enhanced "Secreted in male reproductive system" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 35: Glandular cells - Unknown function" "HPA051839: AB_2681632" "unprognostic (3.58e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-3)" "unprognostic (1.66e-3)" "unprognostic (3.11e-2)" "unprognostic (4.35e-1)" "unprognostic (3.18e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-2)" "unprognostic (8.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.20e-3)" "unprognostic (3.27e-3)" "unprognostic (2.21e-2)" "unprognostic (1.64e-2)" "unprognostic (1.34e-1)" 0.4 2.9 0.4 1.5 0.3 1.1 1.7 1.7 1.2 6.5 0.0 3.0 7.3 4.4 1.1 2.1 0.6 1.0 0.1 0.3 0.8 0.6 1.2 0.3 0.8 1.6 0.8 0.1 0.9 1.0 0.0 0.3 1.6 286.4 3.6 0.5 4.8 2.7 3.5 8.9 5.1 0.3 0.5 0.3 1.9 1.2 0.6 0.1 3.8 1.3 0.8 1.2 0.2 0.5 4.1 1.6 0.2 0.2 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.5 6.4 0.4 0.3 0.1 0.2 7.9 0.0 4.2 0.0 1.1 1.1 1.3 3.8 1.4 0.0 1.4 1.7 0.0 1.9 0.0 0.0 0.2 0.0 0.3 0.7 3.3 0.0 1.0 0.1 2.0 0.1 7.3 0.3 0.3 0.4 0.9 0.0 2.6 0.0 0.4 0.3 5.1 0.0 0.2 4.0 0.3 0.9 0.2 0.2 1.0 0.2 2.0 0.9 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.7 1.2 0.3 0.8 1.6 0.8 1.6 0.5 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.6 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 2.6 0.1 0.0 0.0 0.1 0.2 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 0.0 0.0 0.0 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 106.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.0 0.6 0.0 0.0 3.3 1.0 2.6 KLK5 "KLK-L2, SCTE" ENSG00000167754 "Kallikrein related peptidase 5" Q9Y337 19 50943303-50953093 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 202.7" "Group enriched" "Detected in some" 4 "Early spermatids: 85.4;Late spermatids: 193.2" "Group enriched" "Detected in many" 5 "head and neck cancer: 73.1;melanoma: 32.1;ovarian cancer: 112.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 41 "A-431: 485.1;HaCaT: 455.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014343, CAB025503, CAB026341, HPA073512" Enhanced "Secreted in other tissues" NA NA 2500000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "CAB025503: , CAB026341: , HPA014343: AB_1852603, HPA073512: " "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.30e-4)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.79e-4)" "unprognostic (3.04e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" "unprognostic (2.21e-1)" "unprognostic (2.76e-1)" "unprognostic (2.53e-1)" "unprognostic (9.16e-3)" "prognostic unfavorable (3.85e-6)" 4.6 0.0 1.1 0.0 1.1 0.0 30.2 0.4 2.6 15.6 0.6 0.0 0.1 0.1 0.0 23.0 0.5 0.0 0.2 1.1 0.8 0.5 0.1 6.1 0.0 1.0 1.0 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 23.6 0.0 1.1 202.7 0.0 0.0 0.5 0.3 0.0 14.2 1.6 0.1 0.1 0.0 0.6 0.0 13.5 0.7 485.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.1 455.4 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.3 0.0 0.0 1.1 0.0 1.5 0.1 0.4 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.4 2.6 1.1 0.8 1.0 1.0 1.0 0.5 1.6 0.7 0.2 16.0 0.0 0.0 0.0 26.8 1.8 2.4 12.0 0.0 33.0 27.2 0.3 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 85.4 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 193.2 1.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 1.6 0.8 2.8 10.9 0.0 0.3 0.0 0.0 0.1 KLK6 "Bssp, Klk7, neurosin, PRSS18, PRSS9" ENSG00000167755 "Kallikrein related peptidase 6" Q92876 19 50958631-50969673 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 253.0;esophagus: 94.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 23.9;Breast myoepithelial cells: 16.1;Collecting duct cells: 11.0;Oligodendrocytes: 87.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 131.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 575.5;CAPAN-2: 1346.5" "Region enhanced" "Detected in all" "pons and medulla: 167.8" "Region enhanced" "Detected in many" "spinal cord: 371.7" HPA051837 Supported "Nucleoplasm,Nuclear membrane,Cytokinetic bridge" "Secreted in other tissues" Yes No 10000000 "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Nuclear membrane, Cytokinetic bridge" "HPA051837: " "unprognostic (7.30e-2)" "unprognostic (3.32e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.10e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (8.85e-4)" "unprognostic (3.02e-1)" "unprognostic (2.46e-1)" "prognostic unfavorable (7.82e-4)" "unprognostic (4.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (9.07e-2)" "prognostic unfavorable (1.27e-4)" 0.2 0.0 71.8 0.0 135.8 0.0 7.2 170.8 119.8 53.1 45.6 0.1 0.2 1.5 0.4 94.2 28.9 3.5 0.0 72.9 94.3 20.4 0.0 0.0 0.0 213.8 130.8 0.8 0.0 0.0 0.7 0.0 182.1 0.1 0.0 0.0 15.8 2.2 0.0 9.9 0.0 0.0 123.6 5.8 0.1 0.9 118.1 1.5 0.0 0.0 36.4 0.0 27.4 253.0 575.5 0.0 0.0 1.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 67.7 1346.5 0.0 8.1 0.0 0.6 8.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 1.1 131.0 2.2 0.1 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 5.6 18.2 1.0 1.9 0.0 1.1 46.3 0.0 1.3 0.0 0.4 0.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.8 135.8 170.8 119.8 72.9 94.3 213.8 130.8 182.1 123.6 118.1 253.0 0.2 0.0 0.0 0.0 0.2 0.0 1.0 0.5 0.0 0.0 23.9 16.1 0.3 0.0 1.7 11.0 0.0 0.1 0.4 0.0 0.0 0.1 2.3 0.6 7.5 0.4 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 87.9 7.8 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.3 1.6 0.0 0.3 0.1 0.0 0.0 2.4 KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976468-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 94.7;skin 1: 201.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Basal keratinocytes: 5.0;Basal squamous epithelial cells: 4.6;Breast glandular cells: 9.4;Breast myoepithelial cells: 10.4;Squamous epithelial cells: 5.9;Suprabasal keratinocytes: 10.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.0;CAPAN-2: 8.0;HaCaT: 31.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" NA NA 3700000 "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" 7.1 0.1 8.4 0.1 9.2 0.3 11.2 0.9 7.4 19.7 1.0 0.1 0.5 0.7 0.2 94.7 16.3 1.3 0.2 6.5 1.4 12.1 0.1 3.1 0.0 4.3 1.4 0.1 0.1 0.3 0.7 0.0 4.9 0.1 0.0 0.1 21.6 0.2 1.0 201.2 0.0 0.2 2.1 0.8 0.3 0.3 7.4 0.9 0.2 0.0 10.9 0.0 30.9 3.0 5.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.8 8.0 0.0 1.1 0.0 0.1 31.7 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.3 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 8.4 9.2 0.9 7.4 6.5 1.4 4.3 1.4 4.9 2.1 7.4 3.0 0.0 6.4 1.1 0.0 0.0 5.0 0.1 0.5 4.6 0.0 9.4 10.4 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 5.9 10.7 0.0 0.1 0.0 0.1 2.7 KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 118.0;skin 1: 87.1;vagina: 47.2" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 66.0;Suprabasal keratinocytes: 180.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 88.3;CAPAN-2: 112.2;HaCaT: 83.5" "Region enriched" "Detected in all" 5 "hippocampal formation: 36.1" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 3200000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "CAB019393: , HPA035761: AB_2674769" "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (6.17e-4)" 5.7 0.0 0.1 0.0 0.0 0.0 8.4 0.8 0.7 24.7 0.2 0.0 0.0 0.9 0.4 118.0 13.2 0.1 0.2 0.0 0.0 0.4 0.1 0.1 0.0 0.7 0.2 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 17.1 0.1 0.7 87.1 0.0 0.1 0.0 0.2 0.1 1.2 0.2 1.1 0.5 0.0 9.6 0.0 47.2 0.5 88.3 0.0 0.0 0.6 0.0 0.0 12.3 0.0 0.0 0.0 0.0 1.7 112.2 0.0 2.2 0.0 0.1 83.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 10.3 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.7 0.0 0.0 0.7 0.2 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.3 66.0 0.0 0.4 14.8 0.0 13.0 15.6 0.1 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.7 11.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 5.0 1.8 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.3 2.8 6.2 21.1 180.1 0.0 0.2 0.0 0.2 0.1 KLK9 KLK-L3 ENSG00000213022 "Kallikrein related peptidase 9" Q9UKQ9 19 51002508-51009634 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 11.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HaCaT: 1.0" CAB025049 Enhanced "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "CAB025049: " "unprognostic (3.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLKB1 KLK3 ENSG00000164344 "Kallikrein B1" P03952 4 186208979-186258471 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Inflammatory response" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "liver: 328.4" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 280.5" "Cancer enriched" "Detected in some" 17 "liver cancer: 27.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 3.1;SCLC-21H: 2.1;U-937: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 28900000000 5300000000 "Cluster 62: Liver - Hemostasis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (4.80e-2)" "unprognostic (4.53e-3)" "unprognostic (4.36e-2)" "unprognostic (4.17e-2)" "unprognostic (5.93e-2)" "unprognostic (1.90e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-1)" "unprognostic (8.14e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-2)" "unprognostic (1.15e-1)" "unprognostic (1.45e-2)" "unprognostic (6.01e-2)" "unprognostic (7.30e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" 0.6 1.8 5.9 0.3 6.5 0.0 0.6 6.0 7.6 1.4 9.3 2.3 2.8 0.6 1.0 0.4 1.3 2.5 2.6 6.3 6.2 7.7 328.4 1.0 0.7 7.0 6.5 0.7 4.8 1.0 3.6 0.2 6.4 1.7 1.4 13.1 0.7 0.6 2.4 0.3 2.6 0.6 6.1 2.4 0.8 2.0 6.0 0.4 1.9 1.8 0.4 1.5 0.9 6.3 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.1 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.5 6.0 7.6 6.3 6.2 7.0 6.5 6.4 6.1 6.0 6.3 0.1 0.0 0.0 48.3 0.7 0.0 0.1 0.2 0.6 5.1 0.3 0.5 4.3 14.3 0.1 1.8 16.7 0.0 0.5 0.6 0.0 1.8 2.8 0.6 0.2 1.0 3.0 2.7 10.2 0.5 0.0 0.4 0.0 0.4 0.0 0.2 5.7 280.5 0.2 0.0 15.6 0.4 0.0 4.4 0.0 2.2 0.6 0.3 0.0 6.5 0.1 10.6 2.1 8.0 7.7 0.4 1.4 0.0 0.1 0.0 2.6 1.6 1.1 5.1 0.0 0.6 0.3 1.3 1.3 0.1 0.0 0.0 0.6 0.1 0.7 0.1 KMT2A "ALL-1, CXXC7, HRX, HTRX1, MLL, MLL1A, TRX1" ENSG00000118058 "Lysine methyltransferase 2A" Q03164 11 118436490-118526832 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017794, CAB024270, HPA044910" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "CAB017794: , CAB024270: , HPA044910: AB_2679141" "unprognostic (6.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.83e-1)" "unprognostic (4.56e-1)" "unprognostic (4.96e-2)" "unprognostic (1.72e-3)" "unprognostic (4.52e-3)" "unprognostic (6.07e-2)" "unprognostic (1.61e-1)" "unprognostic (8.46e-2)" "unprognostic (3.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.91e-3)" "unprognostic (7.90e-2)" "unprognostic (3.73e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" 9.9 6.7 8.0 8.5 8.6 19.5 9.9 21.2 9.3 10.3 1.6 10.8 5.4 10.7 8.2 6.8 10.3 6.4 6.5 7.4 9.6 6.7 6.0 10.5 12.4 6.3 6.3 21.2 11.1 9.8 10.2 5.6 6.6 9.2 6.4 23.9 9.4 8.4 7.4 10.4 9.8 7.6 3.2 9.7 8.2 5.3 7.0 14.1 9.9 8.4 11.3 10.7 9.3 11.9 17.9 8.6 20.1 14.5 11.1 16.1 6.2 8.7 11.8 9.0 9.6 17.3 11.4 23.1 15.9 10.8 14.6 16.0 22.9 7.2 17.9 26.0 10.0 45.7 8.9 9.3 6.1 28.5 7.8 7.2 7.4 20.3 24.0 8.9 12.8 13.3 32.8 18.8 9.2 12.7 18.2 12.7 13.6 6.6 13.7 13.8 21.9 6.9 9.8 13.8 18.0 11.8 22.0 6.7 3.9 9.8 11.9 9.1 20.4 14.1 12.7 9.4 14.7 5.1 4.4 15.6 4.7 17.6 8.3 2.1 0.6 1.9 1.6 0.6 1.6 2.5 1.8 1.5 0.3 1.8 1.8 1.2 0.5 2.0 0.7 1.4 1.7 0.4 8.0 8.6 21.2 9.3 7.4 9.6 6.3 6.3 6.6 3.2 7.0 11.9 87.1 70.5 65.8 93.4 83.4 86.9 67.6 29.4 64.9 158.1 76.8 73.9 44.5 40.0 32.2 38.6 152.2 13.9 81.0 26.2 3.9 33.0 10.1 62.1 101.4 74.4 66.4 67.3 146.0 25.6 10.2 65.6 44.4 85.2 29.0 57.5 60.0 27.3 16.8 195.2 170.1 29.6 20.3 37.0 63.7 5.8 66.8 44.8 42.7 62.8 49.9 98.9 78.2 106.6 131.9 28.2 20.1 78.6 83.3 88.3 22.7 10.5 52.7 152.4 65.7 113.4 84.6 25.5 30.7 46.3 80.6 6.0 102.8 55.8 30.6 64.8 KMT2C "HALR, KIAA1506, MLL3" ENSG00000055609 "Lysine methyltransferase 2C" Q8NEZ4 7 152134922-152436641 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 363.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 15.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074736 Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA074736: AB_2686709" "unprognostic (7.75e-2)" "unprognostic (3.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.33e-2)" "unprognostic (1.31e-1)" "unprognostic (5.23e-3)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.45e-1)" "unprognostic (1.06e-1)" "prognostic favorable (8.01e-6)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (3.04e-2)" "unprognostic (2.64e-1)" 12.7 11.2 16.7 7.3 25.7 16.4 12.9 16.7 15.7 15.3 5.5 13.1 5.7 14.3 13.7 14.1 11.9 7.7 10.2 13.0 18.9 8.9 10.4 12.7 8.1 25.3 19.4 16.8 18.5 12.4 12.1 10.3 20.6 9.3 7.6 21.7 14.2 9.0 25.9 17.6 12.8 7.5 12.2 12.2 15.2 13.4 19.1 16.1 14.6 16.9 9.5 11.3 12.7 28.6 13.4 6.1 11.6 11.7 19.0 13.9 10.2 4.7 6.4 5.0 5.5 10.9 4.7 22.4 8.9 11.3 9.2 5.2 14.3 7.5 9.2 12.7 6.5 14.0 7.3 4.5 8.9 22.9 12.8 6.6 9.1 7.1 8.2 7.2 8.4 9.7 22.5 15.0 11.7 12.7 14.8 11.1 6.8 8.5 7.9 9.5 12.3 8.4 5.8 10.9 19.6 12.8 13.4 15.8 6.3 10.6 4.6 15.7 12.8 8.0 4.4 9.0 8.9 15.3 7.7 22.4 10.7 14.7 8.4 6.1 3.0 4.4 1.9 2.7 1.6 6.9 2.0 1.5 1.4 3.9 1.9 1.4 15.2 2.2 2.6 3.7 1.3 0.8 16.7 25.7 16.7 15.7 13.0 18.9 25.3 19.4 20.6 12.2 19.1 28.6 62.4 76.9 71.9 292.8 75.0 89.1 38.3 31.5 62.0 89.0 59.6 35.2 65.8 44.3 72.4 46.0 173.0 38.0 61.9 61.7 5.9 37.6 32.1 94.4 92.1 58.9 67.9 55.5 180.7 33.1 51.7 58.3 89.2 200.5 65.2 52.8 56.7 46.0 33.7 80.8 172.2 53.5 42.7 54.7 79.6 17.3 67.4 90.5 42.7 202.4 77.1 57.7 59.8 299.6 363.2 37.6 49.0 60.2 90.3 53.6 36.3 14.7 46.9 73.0 26.3 83.0 55.5 42.3 33.9 80.9 96.3 127.2 76.8 54.8 39.1 61.4 KMT5A "PR-Set7, SET07, SET8, SETD8" ENSG00000183955 "Lysine methyltransferase 5A" Q9NQR1 12 123383773-123409353 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064495 Supported Nucleoplasm,Cytosol NA Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA064495: AB_2685273" "unprognostic (5.62e-2)" "unprognostic (4.45e-2)" "unprognostic (3.90e-1)" "unprognostic (3.04e-1)" "unprognostic (2.20e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.21e-7)" "unprognostic (3.88e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-2)" "unprognostic (6.13e-2)" "unprognostic (3.44e-1)" "unprognostic (4.75e-3)" "unprognostic (4.27e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.06e-1)" 13.7 10.1 22.6 15.3 22.1 39.2 13.1 20.8 23.2 22.2 18.7 17.7 12.8 21.3 12.9 40.7 21.7 13.6 17.0 22.2 20.6 13.7 14.0 15.5 15.4 22.4 22.7 12.0 19.7 11.4 10.7 16.5 22.9 30.2 14.4 11.7 24.0 19.7 24.4 28.1 15.6 16.7 21.4 16.8 16.9 7.9 23.3 17.9 25.7 15.3 16.6 16.6 25.7 23.9 37.3 24.3 27.8 43.5 18.1 30.9 40.1 57.4 26.3 32.0 26.9 28.8 21.9 84.9 33.1 37.5 11.7 35.8 41.6 21.7 33.3 39.3 45.0 68.8 26.4 15.2 26.5 54.8 18.8 15.1 27.1 34.7 32.8 30.2 26.2 36.4 136.8 38.1 27.5 29.9 58.1 84.9 13.8 34.6 29.0 70.4 22.1 24.1 22.8 43.4 37.9 30.9 51.3 28.3 28.6 23.6 39.6 75.3 32.4 35.2 26.0 42.3 42.3 23.0 25.9 75.9 24.6 29.6 29.9 2.3 1.2 4.3 1.3 2.1 2.7 1.7 1.6 2.1 1.0 1.1 0.9 1.1 1.8 2.3 2.1 2.0 1.5 0.3 22.6 22.1 20.8 23.2 22.2 20.6 22.4 22.7 22.9 21.4 23.3 23.9 34.5 12.8 14.5 0.0 12.7 0.0 17.6 0.0 20.5 20.8 32.0 27.3 0.0 7.2 6.8 27.6 6.2 15.1 22.4 10.4 7.9 9.2 10.1 46.8 43.8 20.7 4.9 62.1 0.0 9.4 16.6 14.7 15.8 41.1 2.5 21.3 30.4 19.5 17.7 3.3 0.0 22.2 0.0 16.8 0.0 3.2 16.1 19.6 0.0 0.0 3.4 28.7 7.2 0.0 0.0 13.6 9.6 42.9 15.9 24.1 14.3 13.1 11.7 17.9 6.6 23.2 19.7 9.7 10.2 38.8 0.0 14.2 14.5 18.4 12.7 22.5 KNDC1 "bB439H18.3, C10orf23, FLJ25027, KIAA1768, RASGEF2, v-KIND, Very-KIND" ENSG00000171798 "Kinase non-catalytic C-lobe domain containing 1" Q76NI1 10 133160219-133226412 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.0;pituitary gland: 27.5" "Cell type enhanced" "Detected in many" "Astrocytes: 93.4;Excitatory neurons: 41.9;Inhibitory neurons: 36.3;Respiratory ciliated cells: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;EFO-21: 1.2;MCF7: 1.1;NTERA-2: 1.4;RPMI-8226: 2.1;SuSa: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039624, HPA056143" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" Vesicles "HPA039624: AB_10671045, HPA056143: " "unprognostic (2.32e-1)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (1.59e-3)" "unprognostic (1.96e-2)" "unprognostic (2.76e-1)" "unprognostic (5.61e-2)" "unprognostic (2.75e-2)" "unprognostic (6.77e-2)" "unprognostic (1.15e-1)" "unprognostic (6.80e-3)" "unprognostic (2.46e-3)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (2.53e-1)" "unprognostic (1.94e-1)" "unprognostic (9.41e-2)" 1.5 13.7 31.1 0.1 17.9 0.0 0.2 8.4 44.0 2.3 0.0 0.3 0.0 2.8 0.7 0.2 9.0 0.2 0.3 19.8 9.1 0.8 6.5 2.8 0.0 17.3 13.3 8.5 0.5 0.4 27.5 0.4 10.3 1.1 0.0 0.9 0.6 0.9 0.0 0.2 0.2 0.4 3.0 0.5 0.3 1.8 22.7 0.0 2.5 0.0 0.0 0.2 0.9 13.1 0.2 0.3 0.2 1.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.6 0.2 0.0 1.2 0.1 0.5 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 31.1 17.9 8.4 44.0 19.8 9.1 17.3 13.3 10.3 3.0 22.7 13.1 0.0 0.0 9.0 93.4 0.2 0.0 0.1 0.4 0.0 1.6 0.2 0.0 2.4 1.5 4.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 14.2 1.5 0.2 3.0 0.0 41.9 0.0 0.1 1.4 0.0 0.3 0.0 1.5 0.4 4.6 0.2 1.7 36.3 0.0 0.0 1.0 0.4 1.0 3.7 1.2 0.0 5.6 0.3 4.5 0.0 6.6 2.1 0.0 0.0 1.2 0.0 0.1 0.0 0.0 25.9 1.0 0.0 0.1 0.5 0.0 1.7 0.0 0.3 0.1 0.4 1.2 0.0 0.0 KNG1 "BDK, BK, KNG" ENSG00000113889 "Kininogen 1" P01042 3 186717348-186744410 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis, Inflammatory response" "Protease inhibitor, Thiol protease inhibitor, Vasoactive, Vasodilator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 3195.2" "Group enriched" "Detected in some" 25 "Distal tubular cells: 655.4;Hepatocytes: 1816.9" "Cancer enriched" "Detected in some" 126 "liver cancer: 608.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;Hep G2: 1.7;RH-30: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001616, HPA001645, CAB009809" Enhanced "Secreted to blood" NA NA 90000000000 47000000000 "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "CAB009809: AB_2134781, HPA001616: AB_1079216, HPA001645: AB_1079215" "unprognostic (3.88e-1)" "unprognostic (1.63e-1)" "unprognostic (2.82e-1)" "unprognostic (3.27e-1)" "unprognostic (8.30e-3)" "unprognostic (2.04e-1)" "prognostic favorable (1.28e-6)" "unprognostic (1.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (9.96e-2)" "unprognostic (1.65e-1)" "unprognostic (3.45e-3)" "unprognostic (5.20e-2)" "unprognostic (2.46e-1)" "unprognostic (4.52e-2)" 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 464.1 3195.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.7 5.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 48.6 0.0 33.1 0.0 0.0 0.0 1.8 655.4 0.0 0.4 0.0 0.0 1.5 0.0 40.2 1.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 30.0 1816.9 0.1 0.0 0.8 0.1 0.0 47.2 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.5 0.1 1.1 0.0 0.0 0.0 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 2.7 0.0 0.1 0.1 KNTC1 "KIAA0166, ROD" ENSG00000184445 "Kinetochore associated 1" P50748 12 122527246-122626396 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 42.3" "Cell type enhanced" "Detected in many" "Early spermatids: 30.4;Erythroid cells: 29.5;Plasma cells: 28.7;Spermatocytes: 40.7;Spermatogonia: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA025241 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA025241: AB_1852629" "unprognostic (1.17e-1)" "unprognostic (2.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.53e-2)" "unprognostic (9.34e-2)" "prognostic favorable (8.69e-4)" "prognostic unfavorable (4.79e-6)" "unprognostic (4.04e-2)" "unprognostic (7.20e-3)" "unprognostic (1.59e-2)" "unprognostic (4.78e-2)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.89e-8)" "unprognostic (2.17e-2)" "unprognostic (3.08e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" 7.1 7.6 3.7 11.7 3.6 42.3 7.6 4.9 5.3 9.1 3.5 9.8 9.0 5.3 5.2 12.2 6.8 3.4 4.1 3.6 3.4 6.7 6.4 8.0 16.4 3.8 3.4 8.2 6.6 2.9 5.7 5.8 3.9 7.3 11.9 5.5 7.7 2.9 2.5 15.1 14.5 4.6 3.1 18.2 7.2 28.2 4.0 17.8 5.4 1.4 17.4 6.2 8.9 5.0 33.8 27.6 77.8 17.9 5.9 10.8 35.0 30.6 19.8 29.7 27.9 26.2 27.6 40.2 15.6 14.9 19.5 45.4 34.1 19.1 39.1 28.8 23.7 49.7 57.1 27.1 2.0 49.3 32.8 5.8 4.3 30.7 20.2 15.5 20.5 50.5 50.4 29.4 22.6 25.0 40.9 113.0 39.4 16.3 34.5 55.4 37.8 44.8 17.8 35.6 24.1 31.0 55.7 11.7 16.7 46.2 44.4 28.1 15.1 33.7 32.3 33.3 36.3 39.3 42.3 61.0 20.1 31.3 39.6 2.5 0.5 1.8 0.7 0.7 0.6 1.6 1.1 1.3 0.5 0.9 0.8 1.0 1.6 0.9 1.0 0.8 0.5 0.3 3.7 3.6 4.9 5.3 3.6 3.4 3.8 3.4 3.9 3.1 4.0 5.0 4.3 0.0 2.6 3.3 8.1 4.2 1.9 1.9 2.2 2.2 3.1 3.4 1.8 0.0 1.9 5.5 4.2 7.0 3.8 3.0 0.0 1.5 30.4 3.3 3.9 2.9 0.0 29.5 6.2 0.4 5.9 2.9 10.2 5.2 1.3 14.7 2.2 1.3 4.8 0.0 4.5 2.3 0.0 2.2 4.7 17.7 4.7 4.0 1.8 4.7 1.6 1.1 2.1 2.5 4.4 0.8 1.0 3.0 28.7 1.0 1.5 0.5 5.0 5.0 6.6 3.1 2.9 40.7 39.9 4.9 2.3 2.9 5.3 2.1 5.8 1.6 KRBA1 KIAA1862 ENSG00000133619 "KRAB-A domain containing 1" A5PL33 7 149714781-149734575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 40.2" "Cell type enhanced" "Detected in many" "Muller glia cells: 11.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021237, HPA050448" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm Cytosol "HPA021237: AB_2134145, HPA050448: AB_2681129" "unprognostic (2.19e-2)" "unprognostic (9.01e-2)" "unprognostic (8.06e-2)" "unprognostic (7.48e-3)" "unprognostic (6.75e-3)" "unprognostic (5.59e-2)" "unprognostic (1.01e-5)" "unprognostic (3.41e-2)" "unprognostic (1.51e-2)" "unprognostic (1.42e-1)" "prognostic favorable (2.77e-4)" "unprognostic (2.55e-1)" "unprognostic (6.33e-3)" "unprognostic (9.62e-2)" "unprognostic (4.29e-2)" "unprognostic (1.47e-1)" "unprognostic (9.31e-2)" 4.1 6.0 6.0 5.0 6.7 3.9 5.4 4.3 10.1 9.2 1.8 9.0 1.5 9.6 2.3 5.7 7.0 4.3 40.2 6.5 4.2 7.6 2.6 4.7 4.6 7.6 4.7 8.9 7.6 6.0 25.2 2.3 4.8 8.9 1.3 4.9 12.9 5.6 6.3 6.9 5.3 6.4 2.6 6.8 7.4 6.8 5.6 3.9 6.1 4.1 3.7 8.1 7.5 7.1 8.0 4.9 9.5 20.0 4.2 4.1 8.3 4.2 5.1 6.6 7.5 0.5 2.1 2.4 8.6 5.3 13.3 7.8 7.2 14.0 3.3 11.1 13.7 4.4 7.5 4.7 5.2 0.0 12.0 9.2 6.5 4.6 2.5 7.8 6.1 13.0 18.4 2.5 3.4 3.2 11.7 6.8 11.4 3.7 4.7 12.2 3.8 1.3 5.1 6.3 7.5 12.7 6.4 18.3 4.5 4.3 3.2 6.8 6.2 8.0 3.4 0.0 5.8 11.7 4.1 10.7 4.7 7.6 8.5 0.0 0.7 0.1 1.4 0.7 0.9 0.6 0.7 0.8 1.0 1.3 1.2 1.0 0.5 0.1 1.6 1.4 1.6 0.7 6.0 6.7 4.3 10.1 6.5 4.2 7.6 4.7 4.8 2.6 5.6 7.1 2.0 0.0 3.2 9.4 1.9 1.8 2.6 2.7 4.6 7.9 4.4 3.9 10.3 5.7 1.6 3.7 4.2 1.2 4.8 0.0 0.0 4.9 0.6 0.8 2.0 1.6 0.0 0.4 6.9 2.7 2.3 3.0 2.6 0.9 0.0 6.3 1.4 1.2 5.2 8.4 6.5 0.1 0.0 2.8 0.9 1.2 4.1 1.8 0.0 1.9 1.6 11.7 2.1 5.5 3.3 1.3 0.0 3.4 1.1 3.0 0.0 1.8 1.6 4.2 6.6 2.8 2.2 1.8 3.5 1.2 1.8 1.2 2.8 3.0 0.1 1.9 KRBA2 ENSG00000184619 "KRAB-A domain containing 2" Q6ZNG9 17 8356902-8376704 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 34.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 16.7;Rod photoreceptor cells: 30.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA022849 Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA022849: AB_1852996" "unprognostic (9.17e-2)" "unprognostic (1.81e-1)" "unprognostic (1.92e-1)" "unprognostic (3.10e-2)" "unprognostic (2.98e-2)" "unprognostic (8.35e-3)" "unprognostic (7.44e-2)" "unprognostic (1.07e-1)" "unprognostic (2.80e-2)" "unprognostic (2.13e-1)" "unprognostic (7.61e-4)" "unprognostic (6.14e-2)" "unprognostic (5.02e-7)" "unprognostic (1.82e-1)" "unprognostic (2.55e-1)" "unprognostic (3.52e-2)" "unprognostic (1.08e-1)" 1.7 1.9 3.4 1.7 4.8 1.1 2.5 5.3 4.5 2.4 2.5 1.5 1.6 2.4 2.5 1.4 1.7 1.2 6.9 3.4 3.6 3.6 0.8 1.6 1.6 3.8 3.6 2.6 1.7 3.9 1.8 1.8 3.9 2.6 1.6 34.5 2.4 1.7 6.2 3.0 1.7 1.8 2.5 1.7 1.6 2.0 4.1 2.5 2.8 6.8 1.3 1.7 1.5 6.8 0.4 3.6 4.6 4.4 2.0 2.8 2.3 0.6 1.3 1.6 2.3 0.0 1.5 0.3 2.6 0.5 1.1 0.9 1.6 0.5 2.2 1.9 1.0 0.6 2.5 1.3 0.7 0.2 1.0 2.5 0.2 1.8 0.6 1.0 2.9 2.3 0.1 0.6 1.4 0.7 1.9 0.5 0.7 0.2 1.2 3.4 2.5 0.4 1.2 2.4 1.6 3.0 3.4 1.2 1.0 3.1 1.5 0.2 1.5 1.3 2.2 0.5 0.7 1.6 0.9 0.3 1.6 0.1 3.1 10.1 1.3 2.3 2.0 1.2 1.9 1.7 2.0 1.6 0.8 2.9 3.5 1.9 1.6 1.5 2.7 1.6 2.2 0.4 3.4 4.8 5.3 4.5 3.4 3.6 3.8 3.6 3.9 2.5 4.1 6.8 9.9 0.0 1.1 6.2 2.2 0.3 1.3 1.3 4.6 3.6 2.9 3.0 0.7 1.5 0.4 1.8 16.7 2.5 1.7 1.5 3.9 3.4 0.4 0.9 3.0 4.5 4.2 7.4 2.6 1.1 0.6 2.8 2.6 0.9 5.1 3.5 2.2 0.4 0.9 3.3 4.1 1.5 2.0 1.0 1.0 0.6 1.5 1.2 1.8 1.9 1.2 2.9 4.1 5.5 4.1 2.1 0.1 3.0 3.8 0.6 1.3 1.4 2.3 30.2 0.0 2.4 2.9 2.3 2.4 3.1 0.9 1.2 2.4 2.5 1.6 0.3 KREMEN2 "KRM2, MGC10791" ENSG00000131650 "Kringle containing transmembrane protein 2" Q8NCW0 16 2964216-2968383 "Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 4.1;skin 1: 7.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 14.1;Basal squamous epithelial cells: 23.3;Intestinal goblet cells: 14.0;Rod photoreceptor cells: 10.9;Spermatocytes: 9.7;Spermatogonia: 18.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.2;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Cell line enhanced" "Detected in many" "HMC-1: 29.3;MCF7: 15.0;RPMI-8226: 28.8;T-47d: 14.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA003223 Uncertain Approved Nucleoli "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoli "HPA003223: AB_1079217" "unprognostic (8.36e-2)" "unprognostic (4.65e-1)" "unprognostic (6.24e-3)" "unprognostic (4.61e-2)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (4.02e-3)" "prognostic unfavorable (8.98e-4)" "unprognostic (3.34e-2)" "unprognostic (1.57e-2)" "unprognostic (8.03e-2)" "unprognostic (8.57e-2)" "unprognostic (7.79e-12)" "unprognostic (6.69e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-2)" "unprognostic (6.58e-3)" 0.1 0.1 0.7 0.3 0.7 0.7 0.1 0.0 0.6 1.5 0.0 0.3 0.1 0.1 0.1 2.0 0.3 0.1 0.0 1.1 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.3 0.0 4.1 0.4 0.0 0.3 7.7 0.6 0.0 0.0 0.2 0.2 1.7 0.0 2.1 0.0 0.0 0.8 0.0 0.5 0.1 1.8 1.1 0.4 10.2 0.0 0.0 1.5 0.6 0.0 0.0 0.0 4.2 1.5 7.8 2.1 0.0 1.1 8.6 1.3 0.7 0.0 1.1 1.2 0.5 2.9 2.6 0.0 0.6 29.3 0.2 0.0 0.0 0.1 0.9 0.0 0.8 3.3 2.9 0.0 15.0 1.8 3.5 2.9 3.0 2.2 4.7 11.8 28.8 0.1 0.3 2.9 1.8 2.0 4.7 5.2 0.4 14.9 2.8 0.2 0.9 12.2 1.0 0.7 5.3 1.3 4.7 0.4 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.7 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 1.4 14.1 0.9 0.3 23.3 0.4 1.0 0.9 0.9 0.0 0.0 0.0 6.2 0.2 0.0 1.1 0.0 0.1 0.7 0.4 0.1 0.1 0.0 0.0 0.4 2.7 1.8 0.1 0.0 0.9 4.5 0.0 0.0 0.0 0.1 0.0 0.1 14.0 0.0 0.0 0.6 0.6 0.0 0.2 3.6 0.0 0.1 0.5 0.0 0.0 0.0 0.2 1.3 0.0 0.1 2.1 0.5 0.0 0.0 10.9 0.0 0.0 0.3 9.7 18.0 1.2 5.5 0.1 0.6 0.0 0.5 0.4 KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 382.1;skin 1: 949.4;urinary bladder: 632.2" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13196.1;Prostatic glandular cells: 5931.6;Urothelial cells: 8499.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 3317.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "hTCEpi: 20287.9;SiHa: 8539.7" "Not detected" "Not detected" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 610000000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" "CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204" "prognostic favorable (4.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.65e-3)" "unprognostic (4.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.36e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (3.89e-1)" 5.1 0.4 4.9 0.8 5.3 2.8 382.1 3.5 5.8 102.2 3.5 2.0 0.8 4.3 14.1 320.4 6.9 1.9 2.7 6.3 3.3 3.1 0.6 9.8 0.3 3.5 3.4 0.9 2.6 0.5 6.6 7.0 3.5 132.4 0.3 0.3 263.2 116.1 0.9 949.4 0.6 1.0 3.4 0.4 2.3 4.5 3.3 142.7 1.6 0.0 97.8 632.2 212.3 4.7 212.5 0.2 0.0 0.0 0.8 0.9 48.8 1.9 0.4 2.8 2.7 16.8 1.9 1.0 14.7 0.2 0.4 2101.7 0.1 2129.1 1.9 0.3 1.6 2.0 910.8 2.0 0.5 1.9 2.2 0.4 20287.9 1.3 1539.9 0.0 1.0 0.0 1.0 1.5 0.4 0.7 0.7 0.3 0.4 237.2 0.0 0.7 3.1 1.7 0.8 770.5 0.3 0.2 8539.7 3.8 0.9 4.8 0.3 1.4 0.8 0.0 401.5 0.2 1.0 0.9 0.4 3.1 1.4 77.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 3.5 5.8 6.3 3.3 3.5 3.4 3.5 3.4 3.3 4.7 5.6 22.4 7.2 0.3 0.5 139.6 13196.1 338.0 327.8 0.2 158.4 792.8 0.1 0.0 415.8 36.8 0.0 21.5 3.8 0.9 0.0 567.7 0.4 116.9 13.5 54.5 1.8 0.0 3.2 202.1 148.5 87.9 0.0 134.1 3.8 0.0 0.0 0.0 3.8 20.2 0.5 0.6 36.7 0.0 14.1 1.6 2.1 37.5 10.6 3.7 6.7 0.0 0.0 0.5 1.4 1754.5 2.5 212.5 0.0 5931.6 0.1 0.4 100.1 0.0 0.0 0.9 101.0 0.3 0.4 48.2 124.3 5.7 60.8 3.1 0.8 8499.3 KRTDAP "KDAP, UNQ467" ENSG00000188508 "Keratinocyte differentiation associated protein" P60985 19 35487324-35495558 "Plasma proteins, Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skin 1: 6146.5;vagina: 1735.6" "Cell type enriched" "Detected in some" 15 "Suprabasal keratinocytes: 5277.0" "Group enriched" "Detected in many" 7 "head and neck cancer: 486.4;melanoma: 207.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "hTCEpi: 100.2" "Region enriched" "Detected in single" 6 "white matter: 1.6" "Not detected" "Not detected" HPA063474 Enhanced "Secreted in other tissues" NA NA 34000000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "HPA063474: AB_2685019" "unprognostic (4.55e-2)" "unprognostic (2.46e-1)" "unprognostic (1.64e-1)" "unprognostic (6.11e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (3.05e-1)" "unprognostic (3.80e-2)" "unprognostic (1.50e-1)" "unprognostic (2.76e-1)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-2)" 5.5 1.0 1.0 0.0 1.6 1.8 406.4 0.9 1.8 845.7 1.1 1.8 0.1 0.8 0.7 111.0 1.3 0.0 2.5 1.0 1.0 0.8 3.0 1.7 0.0 1.1 0.9 1.7 3.4 0.7 1.3 0.0 1.2 1.6 0.0 0.1 205.3 0.3 22.5 6146.5 1.3 0.1 1.0 0.8 1.5 3.3 0.9 20.0 2.5 0.3 90.1 0.7 1735.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.1 0.2 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.2 0.0 0.0 0.4 100.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.6 0.9 1.8 1.0 1.0 1.1 0.9 1.2 1.0 0.9 1.0 0.3 0.0 0.0 0.0 0.0 348.5 0.8 0.4 0.0 0.0 0.5 1.5 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 18.4 0.2 0.1 3.6 0.0 0.0 0.1 0.2 0.0 4.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.7 63.4 0.9 0.1 42.7 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 2.4 42.9 19.1 0.0 5277.0 0.0 1.5 0.0 0.0 0.5 L1CAM "CD171, HSAS, HSAS1, MASA, MIC5, S10, SPG1" ENSG00000198910 "L1 cell adhesion molecule" P32004 X 153861514-153886173 "CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hereditary spastic paraplegia, Hirschsprung disease, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;intestine: 48.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 84.6;Excitatory neurons: 23.7;Horizontal cells: 33.7;Inhibitory neurons: 23.3;Melanocytes: 44.4" "Cancer enhanced" "Detected in many" "melanoma: 34.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 372.4;BJ hTERT+ SV40 Large T+ RasG12V: 200.8;HeLa: 258.1;RH-30: 162.6;RPTEC TERT1: 218.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010896 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 67000000 "Cluster 24: B-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Plasma membrane" "CAB010896: AB_609903" "unprognostic (1.33e-3)" "unprognostic (3.43e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.51e-10)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (9.44e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.13e-1)" "unprognostic (9.12e-2)" "unprognostic (8.52e-3)" "unprognostic (8.02e-2)" "prognostic unfavorable (1.17e-4)" "unprognostic (3.07e-1)" "unprognostic (6.31e-2)" "unprognostic (1.69e-1)" "unprognostic (7.47e-3)" 3.5 27.2 20.4 7.6 23.0 0.5 2.1 23.0 42.8 8.4 0.0 48.5 4.2 2.4 2.1 4.4 3.4 2.4 12.1 12.6 42.4 18.5 0.9 0.6 3.2 9.0 2.5 1.3 2.2 0.1 14.4 0.6 6.1 8.3 4.7 15.7 4.8 9.0 0.9 9.2 13.0 5.4 0.0 0.9 11.3 0.8 3.2 0.7 2.5 2.1 1.8 6.1 9.6 13.2 95.2 7.2 27.6 0.2 0.0 0.0 11.8 131.6 372.4 123.6 200.8 37.8 1.0 0.0 121.8 0.9 103.2 3.9 3.5 2.3 64.1 0.3 1.0 0.0 258.1 6.1 0.4 0.3 20.4 0.9 1.6 18.7 12.9 0.2 0.1 0.1 0.3 0.3 0.6 127.9 0.4 2.6 6.5 0.4 4.7 0.2 162.6 0.9 218.4 1.9 81.4 53.0 73.4 64.2 54.1 61.0 6.7 1.7 0.3 0.1 52.6 5.8 63.7 1.1 1.6 1.0 0.9 1.1 105.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 23.0 23.0 42.8 12.6 42.4 9.0 2.5 6.1 0.0 3.2 13.2 0.4 0.0 0.0 2.6 1.3 1.1 0.1 0.6 3.4 11.6 0.0 0.4 1.2 0.0 0.0 84.6 4.2 0.3 0.1 0.0 0.0 0.5 0.0 0.3 0.1 1.9 0.0 0.0 23.7 0.0 0.2 1.3 0.0 0.6 0.0 0.0 1.4 0.0 0.1 33.7 23.3 0.0 0.0 0.0 1.1 0.0 0.9 0.3 44.4 5.6 0.0 1.5 0.0 1.5 1.7 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.1 10.4 0.0 2.2 0.6 0.4 0.1 0.0 1.3 0.1 1.5 0.0 0.0 0.1 L3MBTL2 "dJ756G23.3, DKFZP761I141, H-l(3)mbt-l" ENSG00000100395 "L3MBTL histone methyl-lysine binding protein 2" Q969R5 22 41205282-41231271 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000815 Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA000815: AB_1079220" "unprognostic (2.42e-1)" "prognostic favorable (6.39e-5)" "unprognostic (3.98e-2)" "prognostic favorable (4.37e-4)" "unprognostic (3.48e-1)" "unprognostic (1.19e-2)" "unprognostic (4.16e-3)" "unprognostic (1.03e-2)" "unprognostic (2.19e-1)" "unprognostic (2.26e-1)" "unprognostic (7.95e-3)" "unprognostic (1.05e-1)" "unprognostic (2.10e-2)" "unprognostic (2.07e-3)" "unprognostic (1.81e-1)" "unprognostic (2.70e-2)" "unprognostic (2.19e-1)" 9.8 14.6 15.8 12.3 16.6 11.0 10.5 14.7 16.8 12.8 12.6 13.5 8.6 13.2 12.1 12.1 19.4 9.5 13.2 15.4 16.3 14.2 16.6 11.8 17.7 16.3 16.4 14.0 11.0 17.0 16.4 9.5 17.0 14.2 10.2 10.0 13.0 13.8 11.9 13.7 11.6 13.9 14.7 15.5 12.7 14.9 16.6 15.0 12.2 9.0 18.0 13.9 10.4 24.3 21.3 20.8 17.6 35.6 20.9 15.6 20.6 19.8 22.7 37.7 31.1 13.7 15.0 34.6 15.7 26.7 22.6 20.3 40.9 26.3 23.9 42.3 52.8 14.4 35.7 32.9 22.1 65.8 31.4 21.4 10.2 29.6 27.8 16.4 27.2 26.1 24.9 27.5 18.1 37.4 33.4 22.4 23.9 75.6 23.8 34.1 14.3 39.9 19.0 20.9 14.3 10.0 35.5 25.3 21.4 17.0 16.9 36.0 21.6 20.2 19.1 16.2 22.2 22.6 43.1 28.6 23.3 29.7 26.3 10.0 13.4 10.7 21.4 16.6 19.6 15.7 16.7 17.1 17.0 11.0 20.0 18.9 2.1 21.2 18.6 12.9 18.4 21.6 15.8 16.6 14.7 16.8 15.4 16.3 16.3 16.4 17.0 14.7 16.6 24.3 9.4 16.0 19.6 7.5 12.2 2.7 5.1 8.0 2.8 24.7 9.0 8.9 10.2 15.7 17.1 11.0 16.7 17.7 15.8 9.6 11.7 9.9 13.9 14.8 9.1 9.3 15.0 10.5 9.9 7.9 17.4 9.3 13.7 8.0 11.4 12.0 7.9 14.2 13.0 16.8 10.8 8.7 22.4 11.1 4.6 30.0 7.2 11.6 3.6 3.7 11.2 13.7 12.3 9.5 8.1 7.6 5.8 9.4 13.3 6.9 7.3 8.7 22.6 15.0 6.6 9.4 13.4 21.5 14.4 6.7 3.8 17.1 13.9 17.5 9.4 6.2 LACRT LACRITIN ENSG00000135413 Lacritin Q9GZZ8 12 54630811-54634895 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "salivary gland: 13.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 304 "breast cancer: 15.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA 230000 "Cluster 24: Salivary gland - Salivary secretion" 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LACTB "FLJ14902, MRPL56" ENSG00000103642 "Lactamase beta" P83111 15 63121833-63142061 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Protease" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036361, HPA036362" Supported Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "HPA036361: AB_10672244, HPA036362: AB_10670798" "unprognostic (6.07e-2)" "unprognostic (2.02e-1)" "unprognostic (2.22e-2)" "unprognostic (2.87e-1)" "unprognostic (1.20e-2)" "unprognostic (3.10e-2)" "unprognostic (8.08e-2)" "unprognostic (6.25e-2)" "unprognostic (8.98e-2)" "unprognostic (3.08e-1)" "unprognostic (6.22e-3)" "unprognostic (5.16e-3)" "unprognostic (6.28e-2)" "unprognostic (3.24e-1)" "unprognostic (8.64e-2)" "unprognostic (7.90e-2)" "unprognostic (3.88e-3)" 17.3 25.4 7.1 21.2 7.4 57.0 12.5 7.2 8.0 8.4 10.8 18.5 19.6 7.6 8.4 14.9 7.0 14.3 22.2 7.2 7.3 23.6 42.4 19.0 19.8 7.3 7.5 8.1 10.6 9.9 6.7 11.8 7.4 9.2 15.9 4.7 9.9 6.8 49.2 12.0 16.9 9.0 7.2 18.3 12.8 22.1 8.3 9.1 9.3 36.3 13.2 19.7 9.2 8.4 60.3 37.0 10.4 7.3 51.9 27.4 8.7 25.7 39.4 43.3 79.9 9.3 37.5 8.0 31.0 37.5 46.9 16.6 35.6 16.7 54.2 55.1 8.9 15.6 12.2 23.7 48.0 14.2 26.1 37.3 35.1 44.5 36.4 64.9 45.2 46.4 14.9 22.1 74.7 22.6 10.9 17.3 15.6 36.7 11.7 8.0 26.6 18.5 23.6 92.5 9.3 4.4 18.6 20.7 59.0 36.0 15.9 23.4 81.5 57.8 44.8 26.2 32.9 23.3 21.8 2.2 44.3 39.2 27.3 4.4 8.4 4.4 1.1 8.3 1.8 3.1 0.9 0.9 9.8 2.6 0.8 1.4 5.3 2.1 7.3 0.8 3.0 2.2 7.1 7.4 7.2 8.0 7.2 7.3 7.3 7.5 7.4 7.2 8.3 8.4 24.6 25.6 22.6 4.9 25.7 58.2 27.2 12.0 19.9 6.5 21.7 16.1 42.5 22.8 10.9 12.9 12.5 15.8 19.3 26.0 25.4 56.0 62.9 13.2 16.4 31.1 7.3 10.8 12.5 43.1 40.5 26.4 17.3 19.3 66.5 12.1 8.9 57.0 88.6 8.4 14.5 27.1 16.2 71.3 72.5 30.6 14.3 97.0 26.6 15.9 152.9 6.9 7.2 10.1 8.1 75.0 19.0 16.1 21.3 35.6 25.2 79.2 9.2 11.3 6.6 37.9 31.5 122.9 25.6 26.3 60.0 18.1 21.8 23.9 20.4 39.6 LAG3 CD223 ENSG00000089692 "Lymphocyte activating 3" P18627 12 6772512-6778455 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.6;ovary: 18.6" "Cell type enhanced" "Detected in many" "dendritic cells: 36.7;Leydig cells: 39.1;Peritubular cells: 69.2;T-cells: 63.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 12.6;MAIT T-cell: 10.0;memory CD8 T-cell: 11.0" "Lineage enriched" "Detected in single" 49 "T-cells: 12.6" "Cell line enriched" "Detected in single" 151 "HDLM-2: 147.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002301, HPA013967" Enhanced "Intracellular and membrane" NA NA 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002301: AB_564101, HPA013967: AB_1846277" "unprognostic (9.39e-2)" "prognostic favorable (3.89e-4)" "unprognostic (8.88e-2)" "unprognostic (7.00e-3)" "unprognostic (1.08e-1)" "unprognostic (6.74e-3)" "unprognostic (8.85e-2)" "unprognostic (4.63e-3)" "unprognostic (1.94e-2)" "unprognostic (1.97e-3)" "unprognostic (8.71e-2)" "unprognostic (9.93e-2)" "prognostic unfavorable (4.62e-11)" "unprognostic (3.07e-2)" "unprognostic (2.70e-1)" "unprognostic (6.13e-2)" "unprognostic (8.19e-3)" 1.7 0.4 0.3 7.3 0.2 1.5 0.9 0.4 0.7 3.8 4.3 4.5 3.3 6.1 2.8 1.3 3.8 1.2 1.5 0.3 0.4 1.0 2.6 2.5 16.2 0.6 0.3 18.6 0.2 0.1 0.7 0.4 0.5 2.6 2.0 0.8 1.1 7.0 0.2 0.4 5.9 1.9 0.7 23.6 2.1 3.4 0.4 1.6 0.8 0.3 10.9 1.6 3.4 0.5 0.1 0.6 0.8 0.5 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.3 0.4 0.0 0.2 0.5 0.0 0.0 0.5 0.1 0.0 147.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.3 0.1 0.2 0.4 0.2 0.5 0.5 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.6 0.0 10.0 0.0 2.4 11.0 0.0 0.0 0.7 4.2 0.0 0.0 0.0 0.2 2.0 1.1 0.3 0.2 0.4 0.7 0.3 0.4 0.6 0.3 0.5 0.7 0.4 0.5 7.7 0.0 3.3 0.0 1.4 5.1 1.6 0.7 9.6 5.9 12.6 15.5 1.6 0.0 4.3 0.0 10.4 0.3 36.7 2.6 0.0 0.2 0.4 1.2 4.9 4.5 21.7 1.7 0.2 0.0 0.2 7.1 1.5 1.9 0.0 1.0 4.2 3.5 11.5 0.0 0.1 6.3 0.0 4.2 6.2 1.5 39.1 3.3 1.8 0.0 3.4 1.4 2.1 0.0 0.0 0.2 0.8 69.2 10.2 2.4 0.7 0.3 0.3 6.7 6.6 5.9 4.9 0.5 2.4 4.5 3.0 0.1 63.6 0.2 2.9 0.6 LAIR2 CD306 ENSG00000167618 "Leukocyte associated immunoglobulin like receptor 2" Q6ISS4 19 54497879-54510687 "CD markers, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.6;pituitary gland: 2.6" "Cell type enriched" "Detected in some" 7 "Extravillous trophoblasts: 696.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "gdT-cell: 14.0;memory CD4 T-cell: 13.8;memory CD8 T-cell: 19.5;naive CD8 T-cell: 13.2;T-reg: 49.5" "Lineage enriched" "Detected in many" 40 "T-cells: 49.5" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Hep G2: 1.0" "Low region specificity" "Detected in some" "Secreted to blood" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.99e-3)" "unprognostic (7.49e-2)" "unprognostic (4.19e-2)" "unprognostic (1.02e-2)" "unprognostic (1.42e-1)" "unprognostic (4.86e-4)" "unprognostic (1.06e-2)" "unprognostic (8.37e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-1)" "unprognostic (2.21e-1)" "unprognostic (9.52e-2)" "unprognostic (3.68e-9)" "unprognostic (1.21e-2)" "unprognostic (3.15e-3)" "unprognostic (3.40e-5)" "unprognostic (6.71e-2)" 0.2 0.0 0.1 0.4 0.3 0.8 0.1 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.1 0.1 0.7 1.6 0.2 0.2 0.0 0.1 0.0 2.6 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 1.1 0.3 0.3 0.4 0.6 0.1 0.2 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 14.0 0.1 0.4 0.0 13.8 19.5 0.1 0.1 2.4 13.2 0.2 1.2 0.3 0.1 49.5 7.8 0.1 0.3 0.1 0.7 0.3 0.3 0.2 0.2 0.4 0.1 0.4 0.5 0.8 0.0 0.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.0 10.7 95.4 0.9 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.4 0.0 0.2 696.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.8 1.8 0.0 0.5 0.0 46.4 0.0 0.1 0.6 0.0 0.0 4.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 32.2 23.2 0.0 0.0 0.0 LALBA LYZL7 ENSG00000167531 "Lactalbumin alpha" P00709 12 48567684-48570066 "Cancer-related genes, Metabolic proteins, Predicted secreted proteins" "Lactose biosynthesis" "Milk protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 926 "breast: 2187.5" "Cell type enriched" "Detected in some" 160 "Breast glandular cells: 48911.9" "Cancer enriched" "Detected in single" 599 "breast cancer: 29.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026343, HPA029855, HPA029856" Enhanced "Secreted in female reproductive system" NA NA 91000 "Cluster 5: Breast - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "CAB026343: , HPA029855: AB_2673222, HPA029856: AB_10671362" "unprognostic (7.85e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 2187.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.6 0.0 0.0 0.0 46.7 0.0 0.0 0.0 0.0 0.0 48911.9 305.6 0.0 0.0 0.0 0.0 0.0 0.0 108.5 0.0 0.0 0.0 0.6 0.0 0.0 15.9 0.0 0.0 0.1 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 58.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.7 0.0 0.0 0.0 32.6 0.0 0.0 0.0 LAMA1 LAMA ENSG00000101680 "Laminin subunit alpha 1" P25391 18 6941742-7117797 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.9" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Distal enterocytes: 173.6;Granulosa cells: 77.3;Intestinal goblet cells: 44.2;Paneth cells: 35.8;Proximal enterocytes: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 56.0;ASC diff: 41.0;BEWO: 199.6;hTEC/SVTERT24-B: 41.7;SK-MEL-30: 38.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB010179 Enhanced "Secreted to extracellular matrix" NA NA "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB010179: AB_2133741" "unprognostic (2.75e-1)" "unprognostic (3.66e-4)" "unprognostic (2.08e-1)" "unprognostic (3.56e-1)" "unprognostic (4.97e-3)" "unprognostic (3.66e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (2.23e-2)" "unprognostic (3.43e-2)" "unprognostic (3.02e-1)" "unprognostic (6.80e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-2)" "unprognostic (4.85e-1)" "unprognostic (3.47e-2)" "unprognostic (7.34e-3)" 0.7 0.0 2.0 0.2 1.5 0.0 1.6 1.9 1.1 0.8 0.5 0.1 0.0 0.9 1.4 0.1 0.2 0.0 0.2 2.0 2.0 2.9 0.1 0.3 0.0 2.0 2.8 1.4 1.1 0.0 1.0 0.1 2.1 0.2 0.0 0.4 1.3 0.6 0.0 0.2 0.0 0.3 2.2 0.1 0.0 5.9 3.0 0.1 2.5 0.0 0.0 0.3 0.2 2.9 0.0 0.0 56.0 0.0 41.0 36.5 199.6 2.0 9.8 9.9 21.5 24.4 0.0 0.0 0.5 3.4 8.0 0.1 0.0 7.3 4.1 0.0 3.2 0.0 11.8 0.0 4.8 0.0 0.0 31.1 1.1 41.7 23.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 2.8 0.0 0.0 38.4 11.6 0.0 0.0 0.0 7.5 20.5 4.2 0.1 0.0 0.0 0.0 3.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 1.9 1.1 2.0 2.0 2.0 2.8 2.1 2.2 3.0 2.9 2.6 6.4 0.0 90.8 0.0 0.0 0.8 0.8 0.6 0.5 2.3 7.2 1.9 4.3 0.0 0.0 0.0 4.1 0.0 173.6 0.0 0.0 1.6 4.1 0.6 0.2 1.2 0.0 1.4 0.5 3.1 4.2 0.0 4.3 0.0 77.3 0.0 0.1 0.9 0.0 1.7 44.2 0.0 0.0 0.0 3.7 0.0 0.2 0.0 15.0 0.0 3.4 0.0 4.0 1.8 0.0 35.8 0.0 0.0 1.0 47.5 1.4 0.1 0.3 0.0 0.6 3.4 0.4 2.5 0.3 0.0 4.8 0.2 4.6 16.5 0.3 LAMA2 LAMM ENSG00000196569 "Laminin subunit alpha 2" P24043 6 128883138-129516566 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 106.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 363.1;Fibroblasts: 151.1;Leydig cells: 184.2;Microglial cells: 692.3;Oligodendrocytes: 160.9;Peritubular cells: 224.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 255.1;ASC TERT1: 184.5;HHSteC: 55.5;HSkMC: 156.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB040310, CAB078182" Enhanced "Secreted to extracellular matrix" NA NA 55000000 "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB040310: , CAB078182: AB_2665829" "unprognostic (1.17e-1)" "unprognostic (5.87e-2)" "unprognostic (2.17e-2)" "unprognostic (3.17e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (9.73e-2)" "unprognostic (3.67e-2)" "unprognostic (2.44e-3)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (4.04e-2)" "unprognostic (1.24e-3)" "unprognostic (6.16e-2)" "unprognostic (5.41e-3)" "prognostic unfavorable (3.65e-5)" 37.6 9.2 2.7 2.6 10.2 0.0 25.0 4.1 5.8 24.1 10.8 14.8 1.7 17.1 4.1 8.0 34.9 18.0 64.0 1.8 3.4 4.1 4.4 26.5 1.0 13.8 4.6 53.4 8.0 2.8 6.9 106.0 8.3 7.3 4.7 2.5 14.9 9.0 22.0 14.1 13.7 14.2 4.7 5.0 17.4 9.2 7.5 2.7 14.6 42.9 0.7 18.1 18.1 6.4 0.0 0.1 2.8 0.1 255.1 184.5 0.0 26.1 9.5 0.6 0.6 0.0 0.2 0.0 0.3 28.2 0.2 0.1 1.6 0.1 0.6 0.1 0.0 0.1 0.0 0.0 55.5 0.0 0.3 156.4 0.1 13.5 0.3 0.2 0.3 0.0 0.0 1.0 44.1 0.0 0.0 0.1 0.5 0.8 0.0 0.0 14.5 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 22.2 1.4 0.1 0.3 8.9 0.3 0.0 1.7 0.0 2.9 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 2.7 10.2 4.1 5.8 1.8 3.4 13.8 4.6 8.3 4.7 7.5 6.4 7.7 0.0 0.5 24.8 0.0 3.7 2.2 0.5 1.2 1.3 1.1 0.8 90.7 0.0 0.9 0.0 0.0 2.1 0.5 0.0 0.0 1.4 7.5 6.5 75.1 8.5 0.0 0.0 363.1 0.2 1.9 151.1 11.7 6.5 0.0 1.0 3.6 0.0 3.0 0.0 8.6 0.0 0.0 0.0 4.4 11.7 184.2 1.9 1.8 692.3 0.1 11.1 3.1 8.0 160.9 0.9 0.0 224.2 0.5 1.0 0.0 0.6 4.5 1.1 118.3 122.1 8.8 2.6 1.9 1.2 2.8 3.8 1.7 44.5 0.0 1.1 LAMA3 "BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa" ENSG00000053747 "Laminin subunit alpha 3" Q16787 18 23689453-23956222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 171.0;Gastric mucus-secreting cells: 138.1;Pancreatic endocrine cells: 585.5;Paneth cells: 170.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HBEC3-KT: 1237.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009309, CAB010757" Uncertain Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 1800000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "CAB010757: AB_477162, HPA009309: AB_1079224" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (6.36e-2)" "unprognostic (3.82e-3)" "unprognostic (2.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (3.58e-6)" "unprognostic (1.98e-1)" "unprognostic (2.36e-1)" "unprognostic (3.15e-1)" "unprognostic (9.91e-3)" "unprognostic (3.98e-2)" "unprognostic (1.13e-1)" 10.0 1.2 8.3 8.5 3.6 0.1 20.3 2.8 5.9 15.4 5.4 13.6 17.8 15.6 4.7 14.5 12.0 7.4 4.2 4.1 3.5 3.2 1.7 20.9 4.1 3.8 5.9 5.7 4.7 10.9 3.0 24.8 3.6 12.2 8.4 3.7 21.3 13.5 2.0 32.1 19.7 6.9 3.5 0.8 31.8 3.3 4.3 9.5 2.3 1.7 4.1 12.2 23.1 2.9 140.5 15.7 0.1 0.1 6.9 1.3 0.3 2.6 1.8 1.3 1.7 5.4 159.5 0.1 17.3 1.8 0.4 248.5 0.2 1237.9 0.9 0.2 8.8 0.0 5.6 2.8 1.2 0.0 0.6 1.6 139.1 0.8 140.0 0.9 5.2 0.2 0.0 0.2 1.6 0.4 0.1 0.1 1.4 42.6 14.4 2.6 0.1 0.2 51.8 15.4 0.6 2.5 4.9 2.0 0.4 0.3 4.5 1.8 12.3 0.9 1.0 6.7 0.6 0.2 0.1 0.6 2.9 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.3 3.6 2.8 5.9 4.1 3.5 3.8 5.9 3.6 3.5 4.3 2.9 28.8 115.4 26.4 13.1 0.7 31.4 104.2 117.1 100.7 6.0 21.8 41.8 2.3 4.3 20.4 1.8 0.0 0.6 0.5 171.0 0.0 30.2 3.9 21.5 4.3 7.5 8.3 0.0 8.3 34.4 0.4 3.6 138.1 24.0 5.7 9.5 2.5 0.9 0.2 0.0 18.5 23.7 4.1 0.0 1.5 4.5 5.9 2.0 1.8 68.4 0.6 0.2 0.0 1.0 2.0 585.5 170.1 3.4 0.2 45.6 39.5 0.0 15.6 2.2 6.6 1.5 22.1 4.5 4.0 28.2 9.9 0.1 1.5 5.9 28.4 18.2 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LAMA5 ENSG00000130702 "Laminin subunit alpha 5" O15230 20 62307955-62367312 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Cytotrophoblasts: 104.4;Glandular and luminal cells: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 114.9;CACO-2: 159.6;EFO-21: 114.4;HaCaT: 107.2;HeLa: 118.3;TIME: 138.4" "Low region specificity" "Detected in many" "HPA058389, CAB078157" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 1800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "CAB078157: AB_2665809, HPA058389: " "unprognostic (8.01e-2)" "unprognostic (2.47e-1)" "unprognostic (1.92e-2)" "unprognostic (3.42e-3)" "unprognostic (1.17e-1)" "unprognostic (9.90e-3)" "unprognostic (4.01e-3)" "unprognostic (5.45e-2)" "unprognostic (8.99e-2)" "unprognostic (1.34e-2)" "unprognostic (5.98e-3)" "unprognostic (2.98e-3)" "unprognostic (4.04e-2)" "unprognostic (9.86e-3)" "unprognostic (2.07e-1)" "unprognostic (9.76e-2)" "unprognostic (1.33e-2)" 27.1 11.8 4.7 5.0 2.2 1.3 27.0 15.2 7.0 26.3 18.9 66.7 5.3 31.3 1.2 24.5 31.8 7.9 26.6 2.4 2.0 32.7 13.2 43.9 3.0 3.2 1.9 9.3 13.9 4.8 12.1 20.0 2.5 36.7 1.2 0.6 17.8 15.4 11.0 36.0 19.9 7.3 0.6 14.0 25.1 4.6 9.3 2.7 28.6 2.8 1.9 32.6 30.2 0.4 15.1 114.9 2.2 14.8 2.7 31.0 85.9 4.2 2.2 3.3 0.6 159.6 59.1 1.3 114.4 0.1 3.6 107.2 3.1 45.8 0.2 0.3 6.5 3.8 118.3 46.1 9.9 0.0 16.6 1.6 29.6 7.9 8.0 5.7 15.0 0.0 7.0 1.7 0.0 22.3 0.1 0.4 7.3 19.3 65.9 0.2 1.4 12.8 28.6 70.3 1.1 44.5 63.2 62.2 1.2 11.6 62.0 0.9 138.4 1.6 41.2 0.7 18.9 0.8 0.2 0.6 31.7 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 2.2 15.2 7.0 2.4 2.0 3.2 1.9 2.5 0.6 9.3 0.4 60.2 76.9 37.1 19.9 6.9 17.1 16.0 56.8 52.9 3.6 16.7 20.8 20.5 12.8 43.9 38.6 8.4 104.4 3.9 0.6 0.0 28.6 4.3 35.5 11.7 49.6 2.4 6.1 5.9 4.5 23.3 13.0 6.1 82.0 2.5 0.9 18.9 12.7 13.1 3.3 12.7 0.3 14.2 0.6 5.4 1.3 9.9 2.2 1.8 10.3 1.1 8.2 1.0 3.5 1.3 13.2 0.1 19.5 8.5 21.9 0.0 12.2 49.6 1.8 26.3 11.0 39.4 0.6 1.7 23.4 12.6 57.3 2.2 1.7 0.6 27.5 LAMB1 CLM ENSG00000091136 "Laminin subunit beta 1" P07942 7 107923799-108003213 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 185.6;Fibroblasts: 99.6;Peritubular cells: 141.8;Theca cells: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 593.0;ASC TERT1: 815.3;HSkMC: 779.6;TIME: 547.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004056, HPA004132, CAB004256" Enhanced "Secreted to extracellular matrix" NA NA 250000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "CAB004256: AB_627867, HPA004056: AB_1079226, HPA004132: AB_1079225" "unprognostic (2.39e-1)" "unprognostic (6.45e-3)" "unprognostic (2.01e-1)" "unprognostic (6.75e-2)" "unprognostic (3.45e-3)" "unprognostic (8.26e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (3.77e-2)" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "unprognostic (3.44e-1)" "unprognostic (5.01e-2)" "unprognostic (2.87e-2)" "unprognostic (4.50e-3)" "unprognostic (1.75e-1)" "unprognostic (4.45e-2)" "unprognostic (1.46e-1)" 141.4 21.8 1.2 26.5 1.6 0.1 74.1 0.9 1.7 46.4 23.0 87.0 29.3 78.9 3.3 25.2 44.1 53.4 53.9 2.4 0.7 81.4 14.7 104.3 9.4 0.0 0.8 29.4 48.2 12.1 11.8 154.3 0.2 18.1 40.4 0.7 24.6 29.7 20.4 39.3 67.5 73.2 0.1 42.4 49.5 11.4 1.4 19.7 43.5 40.6 5.2 53.5 31.0 0.4 94.5 148.6 77.3 3.6 593.0 815.3 291.9 103.5 182.5 68.6 72.1 306.7 166.6 0.0 127.7 200.3 90.8 41.9 24.8 143.6 49.9 0.1 24.8 4.8 52.6 87.9 364.3 0.0 2.8 779.6 49.0 175.9 193.4 409.2 450.0 2.8 17.0 0.0 126.5 29.9 0.1 0.5 42.9 54.9 103.6 0.4 51.9 0.3 238.5 96.0 24.3 142.1 75.1 100.9 68.5 180.2 37.6 1.1 547.1 179.9 44.3 60.2 133.1 0.0 0.2 0.4 89.9 0.0 301.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.9 1.7 2.4 0.7 0.0 0.8 0.2 0.1 1.4 0.4 81.8 0.0 5.6 2.9 2.2 8.9 5.2 16.7 10.8 12.1 2.0 9.5 16.3 15.7 7.6 27.6 4.2 85.5 3.5 10.5 3.9 18.0 2.0 22.6 185.6 57.8 19.2 0.0 51.6 11.2 27.1 99.6 2.6 34.6 2.5 2.9 20.7 3.5 10.1 8.4 23.7 8.0 8.2 2.8 3.8 4.7 71.1 2.4 8.8 11.2 2.0 2.1 5.2 6.0 3.2 21.6 17.0 141.8 0.4 3.6 9.5 11.6 2.9 8.6 52.6 10.2 54.4 5.5 5.1 4.7 6.7 32.6 3.2 174.7 19.2 2.1 LAMB2 "LAMS, NPHS5" ENSG00000172037 "Laminin subunit beta 2" P55268 3 49121114-49133118 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 151.8;Leydig cells: 146.3;Peritubular cells: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 299.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000053, HPA001895, HPA050033, CAB078160" Supported Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 25000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "CAB000053: AB_2313665, CAB078160: AB_2665799, HPA001895: AB_1079227, HPA050033: " "unprognostic (1.12e-2)" "unprognostic (4.40e-2)" "unprognostic (5.14e-3)" "unprognostic (1.10e-1)" "unprognostic (4.08e-1)" "unprognostic (4.01e-1)" "unprognostic (5.59e-2)" "unprognostic (6.80e-2)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (1.26e-1)" "unprognostic (4.96e-2)" "unprognostic (1.21e-3)" "unprognostic (1.78e-1)" "unprognostic (4.38e-2)" "unprognostic (6.20e-2)" "unprognostic (1.24e-2)" 75.2 73.2 12.8 18.2 14.2 2.6 58.2 15.1 14.9 68.0 47.7 63.1 24.6 72.7 25.5 31.9 63.8 62.2 169.1 13.1 14.5 41.3 31.7 55.1 16.9 20.0 14.8 94.4 32.7 104.7 15.4 99.0 15.4 50.4 18.0 11.7 40.3 81.0 67.5 40.9 32.5 80.2 14.1 29.8 48.4 21.4 17.3 6.7 60.2 70.0 12.8 52.2 55.9 13.5 15.7 38.7 34.4 122.0 196.3 201.5 31.1 131.9 161.8 73.8 75.7 18.3 52.0 0.2 44.4 299.0 38.3 49.3 30.0 47.6 52.3 0.1 9.5 6.9 63.4 32.1 132.5 0.3 0.3 176.9 69.4 61.6 62.1 184.3 75.9 0.0 4.1 0.1 61.4 30.3 0.1 0.3 15.1 20.7 32.0 0.2 16.6 0.5 53.5 19.1 0.2 20.4 74.9 42.9 68.3 57.5 93.4 0.9 126.9 82.2 34.9 28.5 35.4 0.1 0.4 0.4 39.1 0.3 57.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 14.2 15.1 14.9 13.1 14.5 20.0 14.8 15.4 14.1 17.3 13.5 83.7 118.6 53.5 26.1 2.4 31.2 13.9 33.6 33.0 1.7 39.4 40.5 151.8 37.1 43.6 55.2 6.2 11.3 0.9 3.6 5.9 26.4 3.5 15.4 24.4 77.8 0.0 0.4 0.2 9.4 6.4 120.1 50.4 27.2 1.3 88.9 94.9 49.9 10.4 8.4 0.4 3.1 32.6 10.1 31.1 12.3 146.3 7.5 42.7 15.9 3.5 46.7 2.1 1.0 0.6 14.1 14.9 140.7 0.5 10.2 16.4 28.6 11.2 2.6 118.3 80.8 92.3 4.3 8.6 14.2 24.4 9.4 3.8 27.6 5.6 9.3 LAMB3 "BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa" ENSG00000196878 "Laminin subunit beta 3" Q13751 1 209614870-209652425 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Amelogenesis imperfecta, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.2;urinary bladder: 73.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 370.0;Basal respiratory cells: 447.6;Pancreatic endocrine cells: 853.8;Urothelial cells: 392.7" "Cancer enhanced" "Detected in all" "head and neck cancer: 223.9" "Region enriched" "Detected in many" 7 "cerebral cortex: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 353.8;HaCaT: 538.2;HBEC3-KT: 1315.0;hTCEpi: 412.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA007584, HPA008069, CAB078183" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 20000 "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB078183: AB_2665825, HPA007584: , HPA008069: AB_1079228" "prognostic favorable (8.43e-4)" "unprognostic (3.08e-2)" "unprognostic (1.46e-2)" "unprognostic (2.88e-2)" "unprognostic (8.00e-2)" "unprognostic (1.60e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.62e-5)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.55e-4)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" "unprognostic (6.01e-2)" "unprognostic (4.92e-3)" 10.9 16.0 2.6 13.1 2.9 10.7 20.7 0.9 21.3 13.2 0.5 26.2 31.5 18.0 2.6 47.2 16.4 11.9 6.8 2.9 2.1 16.3 9.3 28.4 1.2 1.5 1.5 1.1 4.2 0.1 1.7 5.8 1.6 25.9 16.6 0.2 41.5 24.1 6.8 42.1 43.7 2.3 1.7 1.0 73.2 1.0 1.9 5.8 1.2 0.3 13.2 73.1 32.6 2.8 178.4 25.8 0.0 0.4 18.1 11.7 1.0 5.1 15.4 6.0 9.1 68.9 353.8 0.1 15.1 3.7 8.9 538.2 0.1 1315.0 9.1 13.1 1.4 1.1 86.9 1.1 2.4 1.0 1.3 2.6 412.8 19.1 253.4 11.7 6.4 0.1 2.5 6.7 1.9 0.3 0.2 1.2 0.6 81.0 74.0 0.2 17.1 165.4 70.9 109.0 0.5 0.5 73.9 8.5 15.4 1.0 2.0 9.7 138.3 29.1 61.3 1.0 104.6 1.7 3.4 0.4 42.2 0.8 2.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 2.6 2.9 0.9 21.3 2.9 2.1 1.5 1.5 1.6 1.7 1.9 2.8 0.4 221.2 67.7 1.6 1.2 109.7 370.0 447.6 159.9 0.3 11.5 64.4 8.4 4.3 168.5 47.8 0.0 1.1 0.4 247.5 0.0 180.5 6.0 50.8 10.0 3.5 7.8 0.4 2.5 153.0 1.4 7.5 195.7 135.0 18.4 0.2 0.4 3.9 2.0 3.3 2.3 71.7 18.3 0.3 30.0 10.9 1.8 9.9 8.8 0.0 2.1 0.4 0.0 1.0 1.7 853.8 229.1 0.7 2.1 185.0 111.9 2.3 52.2 0.3 0.0 5.3 10.4 0.3 0.6 51.7 26.0 0.5 4.0 0.0 63.1 392.7 LAMB4 ENSG00000091128 "Laminin subunit beta 4" A4D0S4 7 108023548-108130361 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 38.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 34.9;Basal squamous epithelial cells: 41.5;Early spermatids: 12.7;Late spermatids: 11.1;Suprabasal keratinocytes: 13.8" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 1.8;HMC-1: 1.1" "Low region specificity" "Detected in all" "HPA020242, HPA024247" Approved "Secreted to extracellular matrix" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" "HPA020242: AB_2670388, HPA024247: AB_2671496" "unprognostic (7.41e-2)" "unprognostic (1.79e-1)" "unprognostic (4.85e-2)" "unprognostic (1.77e-1)" "unprognostic (3.79e-2)" "unprognostic (6.29e-4)" "unprognostic (8.90e-3)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-3)" "unprognostic (3.27e-2)" "unprognostic (1.23e-4)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" 0.1 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 1.9 0.0 0.1 0.1 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 38.9 0.2 0.0 0.0 0.0 0.3 1.1 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 2.0 0.0 34.9 0.0 0.0 41.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.7 0.0 0.0 5.9 0.0 12.7 3.8 0.1 0.8 0.0 0.0 2.1 0.2 0.4 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 1.9 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.6 0.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 5.1 0.5 4.2 13.8 1.4 0.0 0.1 0.0 0.1 LAMC1 LAMB2 ENSG00000135862 "Laminin subunit gamma 1" P11047 1 183023420-183145592 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 231.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1582.4;ASC TERT1: 863.5;HSkMC: 980.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001908, HPA001909, CAB004486, CAB078163" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to extracellular matrix" NA NA 100000000 "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum, Plasma membrane" "CAB004486: AB_627870, CAB078163: AB_2665817, HPA001908: AB_1079229, HPA001909: AB_1079230" "unprognostic (1.46e-1)" "unprognostic (1.05e-2)" "unprognostic (8.30e-2)" "unprognostic (8.84e-3)" "unprognostic (3.75e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.38e-2)" "unprognostic (2.71e-2)" "unprognostic (1.10e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-3)" "unprognostic (1.10e-3)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.85e-5)" 117.2 16.4 6.3 34.9 7.2 1.1 79.3 9.2 7.1 55.1 13.8 78.3 16.0 63.2 19.3 44.5 63.8 54.7 61.7 7.2 8.7 19.4 13.8 58.7 15.3 6.9 7.7 36.1 19.2 20.0 9.5 231.7 6.0 31.3 34.3 3.7 28.1 50.9 50.5 40.8 48.9 102.3 6.4 8.4 51.1 18.7 8.6 14.7 40.3 60.1 12.0 66.9 47.7 5.4 52.5 83.5 268.4 76.7 1582.4 863.5 405.0 374.8 373.0 147.8 87.1 249.4 58.2 18.8 168.6 180.8 87.9 127.4 51.7 99.2 112.7 0.6 52.6 0.9 71.1 91.3 248.1 16.6 8.9 980.4 52.2 177.0 138.7 262.7 261.0 0.2 0.6 55.5 182.5 22.8 0.2 17.4 109.3 96.0 15.7 13.5 226.2 9.9 237.6 137.0 17.6 50.1 98.9 0.7 95.6 459.0 21.2 43.6 486.5 179.1 70.0 168.2 95.4 21.6 0.3 12.4 148.7 12.3 177.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 7.2 9.2 7.1 7.2 8.7 6.9 7.7 6.0 6.4 8.6 5.4 81.2 35.3 21.6 32.7 8.1 31.4 46.1 44.4 35.9 3.1 7.1 17.4 57.5 27.1 21.0 36.8 4.2 101.9 0.2 1.6 1.9 59.2 5.7 32.5 58.5 80.9 1.2 0.0 69.2 23.3 69.0 187.8 8.6 78.5 2.5 53.0 26.7 19.1 18.7 1.7 50.0 2.4 18.3 10.7 20.6 6.8 120.9 4.5 33.8 106.8 6.0 2.2 1.0 35.2 2.5 44.7 2.6 62.4 11.0 59.9 0.5 12.4 14.8 0.7 72.3 73.9 102.1 17.6 36.8 17.0 16.9 72.1 2.8 74.4 3.5 25.8 LAMC3 DKFZp434E202 ENSG00000050555 "Laminin subunit gamma 3" Q9Y6N6 9 131009174-131094473 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 48.7" "Group enriched" "Detected in many" 4 "Leydig cells: 118.4;Peritubular cells: 364.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.0;EFO-21: 17.3;Hep G2: 6.1;SiHa: 6.7;U-2 OS: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022814 Enhanced "Secreted to extracellular matrix" NA NA 1100000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA022814: AB_2670960" "unprognostic (9.77e-2)" "unprognostic (1.90e-1)" "unprognostic (9.55e-3)" "unprognostic (2.09e-1)" "unprognostic (2.15e-1)" "unprognostic (1.22e-2)" "unprognostic (1.38e-2)" "unprognostic (2.28e-3)" "unprognostic (6.27e-2)" "unprognostic (1.83e-1)" "unprognostic (1.58e-1)" "unprognostic (3.38e-1)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (1.63e-1)" "unprognostic (3.34e-1)" "unprognostic (7.83e-2)" 1.5 13.5 1.3 0.3 1.8 0.0 1.5 1.3 2.4 22.3 1.9 1.6 0.4 3.3 3.5 1.7 1.1 2.7 1.2 1.4 1.2 9.2 4.9 23.3 0.0 1.4 1.3 1.7 3.5 0.9 11.6 48.7 1.2 4.2 0.1 0.0 1.4 3.8 0.3 8.6 0.3 0.3 1.2 11.3 0.5 19.0 1.7 0.2 1.2 1.1 0.0 15.0 8.2 2.0 0.0 0.5 4.0 0.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 17.3 0.0 0.3 0.0 0.3 0.0 0.0 0.0 2.2 0.0 1.5 6.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.2 2.2 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.4 0.1 6.7 0.0 2.6 0.4 0.0 0.7 0.0 0.0 5.3 0.4 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 1.3 1.8 1.3 2.4 1.4 1.2 1.4 1.3 1.2 1.2 1.7 2.0 1.5 0.0 0.0 1.0 0.0 6.8 0.0 0.0 0.0 0.0 0.4 0.4 1.3 0.0 0.0 1.8 0.0 0.7 0.0 0.0 0.0 0.1 1.9 1.6 48.5 1.7 0.0 0.0 1.7 0.0 0.8 20.7 0.0 1.1 0.0 27.8 3.6 0.1 1.5 0.0 4.1 0.2 0.0 0.0 10.2 12.6 118.4 0.5 10.6 36.5 0.1 0.0 0.0 0.0 1.0 0.1 0.0 364.1 0.0 0.2 0.0 0.2 0.0 0.0 46.0 0.1 10.0 1.0 3.5 0.0 4.4 1.0 0.8 38.1 0.0 0.1 LAMP3 "CD208, DC-LAMP, DCLAMP, LAMP, TSC403" ENSG00000078081 "Lysosomal associated membrane protein 3" Q9UQV4 3 183122215-183163839 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lung: 219.7" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 486.7;monocytes: 339.6" "Cancer enhanced" "Detected in many" "lung cancer: 27.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 5.6" "Group enriched" "Detected in many" 8 "granulocytes: 5.6;T-cells: 4.8" "Group enriched" "Detected in many" 4 "EFO-21: 169.5;HDLM-2: 46.6;HHSteC: 60.4;hTCEpi: 59.1;JURKAT: 52.7" "CAB025133, HPA051467" Enhanced Enhanced Vesicles NA NA 59000 "Cluster 13: T-cells - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 38: EFO-21 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Vesicles "CAB025133: , HPA051467: AB_2681495" "unprognostic (1.43e-3)" "unprognostic (2.06e-2)" "unprognostic (1.70e-1)" "unprognostic (2.99e-3)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (7.67e-2)" "unprognostic (8.64e-2)" "unprognostic (4.95e-2)" "prognostic favorable (9.90e-4)" "unprognostic (1.80e-3)" "unprognostic (5.80e-2)" "prognostic unfavorable (1.89e-7)" "unprognostic (3.12e-1)" "unprognostic (4.13e-2)" "unprognostic (8.35e-2)" "unprognostic (1.29e-1)" 0.7 0.6 0.2 33.1 0.4 0.8 1.3 0.3 0.2 1.4 0.0 3.2 2.7 0.7 2.6 4.4 1.1 3.9 0.3 0.2 0.1 0.6 0.9 219.7 16.1 0.2 0.1 0.3 7.8 1.9 0.5 1.9 0.1 2.7 6.8 0.6 27.2 2.5 0.2 7.0 3.1 4.3 0.2 9.0 4.1 22.7 0.3 28.1 7.5 0.2 21.5 11.2 0.9 0.0 10.7 0.3 0.2 1.7 0.1 0.1 8.7 0.2 2.8 1.8 0.5 2.8 5.3 0.1 169.5 0.9 18.9 1.5 3.7 6.4 0.2 46.6 5.9 0.0 0.3 0.4 60.4 0.0 1.4 0.9 59.1 0.1 7.4 0.0 7.6 52.7 0.4 9.9 0.2 0.2 2.5 0.4 0.3 0.9 2.7 0.0 0.0 0.8 0.2 3.4 0.7 0.4 0.8 0.3 5.0 2.1 3.4 0.4 8.3 0.0 3.0 0.4 0.2 3.5 13.2 0.5 0.0 0.1 0.1 0.3 0.0 5.6 0.2 0.0 2.4 0.1 1.8 1.1 0.0 0.2 2.3 1.3 1.3 0.6 0.0 0.0 4.8 0.7 0.2 0.4 0.3 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.3 0.0 0.2 64.1 486.7 0.0 2.0 6.0 2.9 2.4 8.6 0.0 0.3 0.6 1.2 1.5 9.5 1.8 0.0 2.9 0.1 0.1 0.0 0.6 34.3 1.3 0.2 0.5 0.0 0.4 0.7 6.1 0.4 1.0 1.5 0.8 18.9 0.4 0.0 0.0 1.3 0.0 0.6 0.2 0.0 0.0 41.1 84.9 0.6 4.8 1.8 0.0 339.6 0.0 0.0 0.0 0.1 0.6 0.0 0.0 4.1 1.6 0.1 0.0 11.5 0.0 0.0 0.4 0.3 14.0 0.5 4.0 5.7 1.2 2.3 0.0 0.5 2.2 LAMTOR4 C7orf59 ENSG00000188186 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4" Q0VGL1 7 100148907-100155944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 3294.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020998 Enhanced Supported Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA020998: AB_1845762" "prognostic favorable (2.48e-4)" "prognostic favorable (6.08e-4)" "unprognostic (1.29e-2)" "unprognostic (1.14e-1)" "unprognostic (8.21e-3)" "unprognostic (6.11e-2)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (6.17e-2)" "unprognostic (1.57e-1)" "unprognostic (2.42e-3)" "unprognostic (8.83e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (2.68e-1)" "unprognostic (2.45e-1)" "unprognostic (1.68e-2)" 145.5 144.7 207.2 92.8 215.4 194.6 143.4 221.1 260.4 148.0 204.4 180.6 89.4 116.7 65.9 117.5 123.1 97.7 167.4 205.7 212.3 188.5 139.1 128.0 159.0 222.1 211.3 142.7 124.2 126.7 162.7 68.1 213.3 160.8 105.8 39.9 116.8 76.2 137.5 478.7 151.0 69.0 217.6 251.9 162.2 86.6 215.8 104.8 133.8 106.0 85.5 145.8 126.7 224.1 105.9 250.9 130.2 165.4 135.2 154.9 105.7 62.1 151.0 113.1 138.9 116.9 165.7 169.1 204.7 94.2 205.7 108.9 124.0 160.0 48.1 172.4 353.2 135.2 245.0 205.4 127.4 106.4 187.1 187.3 155.4 118.5 145.6 125.7 174.9 155.3 129.9 264.4 156.1 501.0 104.0 424.7 138.7 291.1 199.9 107.4 107.1 302.8 129.1 126.9 91.6 169.0 114.3 265.8 211.3 99.0 107.1 207.0 118.3 107.1 158.6 223.7 101.7 159.1 231.2 324.2 171.0 293.5 155.9 1033.3 843.2 3121.0 299.6 795.1 251.1 541.8 377.5 312.8 570.0 475.4 381.8 307.2 3294.2 310.1 756.2 482.6 453.0 893.6 207.2 215.4 221.1 260.4 205.7 212.3 222.1 211.3 213.3 217.6 215.8 224.1 181.8 93.0 150.7 18.9 195.8 274.9 194.0 282.0 167.9 65.3 240.8 277.2 176.6 143.0 172.9 218.8 12.5 258.4 199.9 819.7 534.1 167.3 40.0 152.9 125.8 186.7 299.3 99.3 12.0 326.2 196.5 175.6 146.3 131.4 183.2 120.9 239.1 246.3 531.1 58.9 13.6 423.9 252.3 497.4 351.7 46.6 146.3 365.2 434.0 13.1 411.0 229.9 298.6 11.6 26.2 204.2 867.4 120.4 133.0 169.5 511.6 557.5 194.8 67.0 144.7 142.1 196.9 88.1 101.2 151.3 662.9 201.4 195.9 150.8 511.8 219.0 LARGE1 "KIAA0609, LARGE" ENSG00000133424 "LARGE xylosyl- and glucuronyltransferase 1" O95461 22 33162226-33922841 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 8.5;Alveolar cells type 2: 8.2;Ductal cells: 7.1;Endometrial stromal cells: 10.5;Exocrine glandular cells: 7.9;Glandular and luminal cells: 8.6;Hofbauer cells: 6.0;Pancreatic endocrine cells: 6.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.3;basal ganglia: 23.4;cerebral cortex: 33.2;hippocampal formation: 45.4;white matter: 16.4" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.16e-1)" "unprognostic (7.77e-3)" "unprognostic (3.79e-1)" "unprognostic (1.74e-3)" "unprognostic (1.63e-1)" "unprognostic (1.48e-2)" "unprognostic (4.90e-2)" "unprognostic (1.39e-2)" "unprognostic (5.21e-3)" "unprognostic (6.00e-2)" "unprognostic (2.12e-2)" "unprognostic (1.35e-2)" "unprognostic (7.12e-3)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (2.93e-1)" "unprognostic (3.96e-3)" 11.9 10.1 18.3 5.9 23.4 0.4 9.1 3.4 33.2 15.3 19.7 27.8 9.2 22.4 8.1 6.7 13.5 9.0 58.4 45.4 2.2 8.4 8.1 6.5 5.1 1.0 2.9 20.8 8.3 6.0 7.4 4.1 4.7 15.2 8.7 13.2 5.9 24.8 49.5 8.5 11.4 15.7 0.0 5.8 16.7 7.6 6.3 2.0 5.3 27.5 5.0 21.6 11.5 16.4 4.1 12.3 19.5 8.4 3.2 0.6 7.4 14.1 7.1 2.7 0.0 2.6 0.4 19.5 2.4 14.0 4.6 1.6 11.6 0.0 0.1 0.3 9.8 0.0 0.0 13.1 4.1 0.1 2.0 1.8 0.9 0.2 0.0 0.0 0.1 0.2 0.2 2.7 3.2 16.5 0.1 9.5 7.7 16.3 0.4 10.6 20.2 3.5 2.5 18.1 7.0 2.4 8.4 11.4 13.6 13.7 16.4 0.6 0.1 8.8 13.8 5.2 3.7 21.3 23.4 0.4 16.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 18.3 23.4 3.4 33.2 45.4 2.2 1.0 2.9 4.7 0.0 6.3 16.4 8.5 0.0 8.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 4.2 4.2 0.0 0.0 2.5 1.8 0.0 0.3 0.9 0.0 0.0 7.1 0.0 5.7 10.5 1.9 0.0 0.0 0.0 7.9 0.7 2.9 0.0 8.6 1.3 3.9 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.4 0.0 0.0 2.0 1.5 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.3 0.8 1.2 0.0 0.0 LARGE2 "FLJ35207, GYLTL1B, PP5656" ENSG00000165905 "LARGE xylosyl- and glucuronyltransferase 2" Q8N3Y3 11 45921621-45929096 "Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 36.6" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 189.8;Syncytiotrophoblasts: 116.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;naive B-cell: 2.1" "Lineage enriched" "Detected in single" 4 "B-cells: 2.1" "Cell line enhanced" "Detected in many" "BEWO: 34.3;NTERA-2: 32.5;SK-BR-3: 23.5;T-47d: 71.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056621 Approved "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA056621: AB_2683194" "unprognostic (9.82e-2)" "unprognostic (3.63e-2)" "unprognostic (3.65e-2)" "unprognostic (2.43e-2)" "unprognostic (6.20e-2)" "unprognostic (4.46e-3)" "unprognostic (1.36e-1)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (2.87e-1)" "unprognostic (3.30e-2)" "unprognostic (6.94e-2)" "prognostic favorable (3.04e-12)" "unprognostic (2.31e-1)" "unprognostic (9.77e-2)" "unprognostic (1.66e-1)" "unprognostic (1.18e-2)" 0.2 2.4 0.0 2.3 0.0 0.5 4.4 0.3 0.1 5.1 12.2 1.0 1.3 2.0 4.9 17.1 3.9 0.6 0.2 0.8 0.0 15.9 3.3 1.9 4.7 0.1 0.1 2.0 27.1 12.5 11.5 36.6 0.0 9.9 0.7 3.5 17.7 8.3 0.6 19.7 3.7 0.1 0.0 2.5 11.2 1.6 0.2 4.1 11.3 0.0 2.3 2.2 6.8 0.1 1.2 1.6 0.1 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 8.5 0.6 0.0 0.9 0.0 0.8 8.0 0.1 15.2 0.0 0.0 4.7 0.0 1.2 9.3 0.2 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 2.0 9.7 0.0 0.0 2.7 0.2 0.0 32.5 12.2 1.1 0.9 0.0 3.1 0.5 0.6 9.6 1.1 0.3 23.5 0.1 1.9 71.4 0.0 0.0 0.2 10.4 0.0 0.0 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 1.4 0.1 0.4 0.0 2.1 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.8 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.2 3.2 2.2 0.0 4.0 0.0 0.0 0.0 0.0 0.0 13.5 8.3 0.0 0.0 0.6 7.3 0.0 189.8 0.4 0.0 3.9 4.6 0.0 10.9 3.4 0.9 0.0 0.0 0.0 6.4 11.3 0.9 0.0 28.0 0.0 9.4 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.1 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 116.2 0.8 0.1 0.0 0.0 LAT LAT1 ENSG00000213658 "Linker for activation of T cells" O43561 16 28984826-28990784 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 117.9" "Group enriched" "Detected in many" 6 "dendritic cells: 80.7;granulocytes: 78.9;Macrophages: 55.9;NK-cells: 152.4;T-cells: 151.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 19 "basophil: 307.7;gdT-cell: 303.4;MAIT T-cell: 212.5;memory CD4 T-cell: 295.1;memory CD8 T-cell: 307.2;naive CD4 T-cell: 276.0;naive CD8 T-cell: 266.9;NK-cell: 114.6;T-reg: 410.8" "Group enriched" "Detected in all" 142 "granulocytes: 307.7;NK-cells: 114.6;T-cells: 410.8" "Cell line enhanced" "Detected in many" "HEL: 189.8;HMC-1: 765.9;MOLT-4: 279.5" "Not detected" "Not detected" "CAB002223, HPA011157, CAB012978, CAB079960" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 140000 "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Golgi apparatus" "CAB002223: AB_563852, CAB012978: , CAB079960: , HPA011157: AB_1079237" "unprognostic (4.35e-3)" "unprognostic (5.17e-3)" "unprognostic (1.25e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-1)" "unprognostic (7.15e-5)" "unprognostic (1.17e-1)" "unprognostic (5.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-2)" "unprognostic (1.52e-3)" "unprognostic (5.33e-2)" "unprognostic (1.02e-8)" "unprognostic (1.04e-2)" "unprognostic (5.58e-2)" "unprognostic (3.25e-1)" "unprognostic (1.51e-4)" 8.1 4.4 9.1 23.9 9.6 17.5 6.6 9.0 11.9 15.6 8.1 31.3 9.2 19.3 5.2 8.1 11.6 9.6 3.9 9.2 8.5 15.3 10.5 14.1 65.9 9.2 8.5 7.7 5.7 2.0 14.2 3.9 9.0 21.6 5.2 3.5 7.8 9.5 4.2 10.7 22.7 5.7 8.0 32.0 13.4 4.1 9.7 117.9 17.6 1.6 29.0 24.7 13.3 8.9 1.0 2.3 1.5 2.5 3.7 2.4 4.9 5.5 1.4 1.7 2.2 2.3 3.0 0.7 7.2 2.2 0.6 2.9 2.6 1.3 0.8 1.6 3.3 189.8 5.4 3.3 1.0 5.9 765.9 2.1 3.8 1.7 0.7 2.8 0.9 62.7 2.6 21.7 0.8 5.6 279.5 38.3 3.4 0.4 2.7 3.2 0.8 24.9 1.9 1.6 5.3 1.0 0.9 1.8 2.7 1.4 2.7 31.7 3.6 3.6 18.0 3.9 1.3 7.6 7.0 3.1 45.5 2.7 2.9 307.7 1.4 0.7 303.4 1.5 212.5 1.7 295.1 307.2 1.1 1.7 276.0 266.9 14.6 114.6 1.3 1.9 410.8 196.5 9.1 9.6 9.0 11.9 9.2 8.5 9.2 8.5 9.0 8.0 9.7 8.9 5.2 0.0 13.1 4.6 6.2 7.1 2.1 1.1 2.8 11.0 3.7 4.3 1.7 7.2 3.1 9.2 6.2 2.6 80.7 1.2 1.9 1.7 0.3 1.5 2.3 4.7 0.0 16.6 4.7 0.5 0.9 3.0 7.7 2.7 78.9 4.9 8.6 2.9 14.3 6.7 5.5 1.5 0.0 7.3 9.4 0.1 1.5 55.9 10.6 5.6 9.2 3.0 152.4 3.0 3.5 1.0 0.7 0.7 17.0 2.2 1.3 1.3 1.3 9.6 0.0 3.0 3.8 1.7 2.1 1.9 5.3 2.7 151.7 1.7 1.4 1.3 LAT2 "HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5" ENSG00000086730 "Linker for activation of T cells family member 2" Q9GZY6 7 74199652-74229834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.3;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "B-cells: 90.6;granulocytes: 171.6;Hofbauer cells: 82.7;Kupffer cells: 71.1;Langerhans cells: 81.9;Macrophages: 89.1;monocytes: 89.6;NK-cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 871.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 192.2;REH: 205.7;RPMI-8226: 73.3;THP-1: 186.5;U-937: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003462 Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA003462: AB_1079238" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (1.32e-2)" "unprognostic (3.55e-3)" "unprognostic (1.09e-1)" "unprognostic (3.30e-3)" "unprognostic (2.79e-2)" "unprognostic (1.33e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (6.34e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" 6.8 5.4 9.7 37.7 11.1 61.3 3.8 11.8 12.8 3.7 9.1 6.5 6.3 2.9 2.5 3.6 4.2 9.1 2.3 10.3 12.2 3.3 4.8 19.2 51.6 18.4 13.6 1.7 3.0 2.2 3.0 7.4 17.7 7.1 7.7 1.2 4.5 3.5 3.3 3.0 13.6 8.8 16.5 47.0 6.5 2.0 15.3 12.2 2.8 2.4 56.6 10.1 2.5 20.1 1.7 1.1 1.1 3.1 0.3 0.0 1.1 1.4 1.2 0.6 0.7 2.3 28.9 19.6 0.4 0.5 6.1 1.2 0.4 1.1 0.6 31.4 1.2 8.6 1.8 1.8 0.1 56.1 55.6 0.4 0.8 2.1 0.6 1.2 0.3 1.1 1.6 9.3 0.5 1.7 1.3 192.2 0.9 5.5 2.0 205.7 1.1 73.3 0.2 1.7 0.9 0.8 0.6 1.2 1.2 0.9 1.1 186.5 2.1 2.1 19.9 0.8 1.8 0.9 6.2 32.2 9.4 177.6 1.5 871.6 276.6 46.0 8.8 159.0 0.9 169.3 2.3 1.4 225.2 191.1 1.0 2.9 491.0 73.9 93.9 8.9 4.9 214.7 9.7 11.1 11.8 12.8 10.3 12.2 18.4 13.6 17.7 16.5 15.3 20.1 1.3 3.2 16.2 0.7 90.6 3.4 0.7 0.0 0.6 0.3 1.0 1.9 1.1 5.7 3.1 3.7 0.0 0.6 47.8 0.2 0.0 0.3 2.4 1.3 0.6 3.9 7.8 16.6 1.7 0.2 1.1 1.7 1.1 2.1 171.6 0.4 3.9 4.5 82.7 0.0 1.4 0.8 0.0 71.1 81.9 3.4 0.0 89.1 1.8 20.6 89.6 0.2 70.0 0.5 0.9 0.6 0.1 0.7 18.7 1.2 0.1 0.2 5.9 1.3 0.0 1.9 0.9 0.4 1.4 0.1 2.6 1.2 27.7 0.3 0.8 0.4 LATS1 WARTS ENSG00000131023 "Large tumor suppressor kinase 1" O95835 6 149658153-149718105 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031804 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 59: Non-specific - Transcription" "HPA031804: AB_10601688" "unprognostic (4.02e-3)" "unprognostic (3.80e-3)" "unprognostic (1.28e-2)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (2.09e-1)" "unprognostic (6.15e-3)" "unprognostic (1.29e-2)" "unprognostic (9.67e-2)" "unprognostic (1.02e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (5.62e-2)" "unprognostic (1.92e-1)" "unprognostic (8.43e-2)" "unprognostic (2.63e-1)" "unprognostic (2.65e-1)" 8.1 8.0 4.8 8.6 4.9 15.4 9.2 11.0 7.0 10.1 5.5 7.3 7.2 12.1 7.4 8.2 9.7 7.7 5.6 5.2 4.6 7.7 7.8 9.1 9.8 4.7 4.3 15.6 6.8 11.7 5.2 8.8 5.0 11.0 8.5 11.0 8.7 7.7 6.4 9.1 7.7 10.7 4.3 10.2 7.7 6.2 5.1 11.7 8.9 8.1 8.4 9.0 7.2 7.6 8.7 6.8 13.7 19.8 12.9 16.6 10.7 11.3 11.4 11.8 11.7 11.1 7.3 14.0 11.1 15.7 9.4 11.8 18.3 12.0 18.5 12.9 14.7 28.1 8.2 9.9 11.9 26.5 19.8 11.3 19.1 13.5 22.7 12.2 14.8 12.1 35.3 13.9 11.9 10.4 13.8 11.0 8.5 8.0 6.5 13.6 16.4 6.5 11.0 12.2 9.3 14.7 16.1 11.5 8.4 9.3 12.0 22.9 18.7 9.5 14.8 11.4 18.2 11.6 13.5 15.8 8.7 14.8 14.3 8.2 3.0 4.8 5.9 5.3 5.3 3.8 4.5 5.0 3.3 4.7 3.8 5.1 2.0 3.0 8.9 2.8 4.8 2.4 4.8 4.9 11.0 7.0 5.2 4.6 4.7 4.3 5.0 4.3 5.1 7.6 21.1 12.8 21.3 33.0 21.9 16.3 11.2 9.7 27.9 20.3 15.2 10.2 9.6 12.8 12.5 7.3 18.8 8.5 18.7 15.3 1.9 7.5 23.0 14.1 23.4 16.2 16.8 17.7 51.4 6.6 11.4 19.7 20.9 17.1 14.0 19.8 21.0 13.3 11.0 13.5 48.0 12.6 6.1 14.7 11.6 6.9 13.7 16.6 14.2 32.8 15.0 10.7 10.3 54.8 64.0 9.9 11.5 25.9 21.9 15.4 13.6 6.6 12.8 22.0 19.7 28.8 15.1 8.8 9.6 18.8 18.0 13.1 23.3 13.8 11.7 11.8 LBP BPIFD2 ENSG00000129988 "Lipopolysaccharide binding protein" P18428 20 38346482-38377013 "Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity, Lipid transport, Transport" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 1338.5" "Cell type enriched" "Detected in some" 30 "Hepatocytes: 458.3" "Cancer enriched" "Detected in many" 20 "liver cancer: 356.7" "Region enhanced" "Detected in single" "medulla oblongata: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 10.7;HSkMC: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001508, CAB025905" Approved "Secreted to blood" NA NA 25000000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB025905: , HPA001508: AB_1079241" "unprognostic (4.20e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (4.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-2)" "unprognostic (5.50e-2)" "unprognostic (2.48e-3)" "unprognostic (6.15e-2)" "unprognostic (2.12e-1)" "unprognostic (7.93e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (3.62e-12)" "prognostic unfavorable (5.76e-4)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" 58.2 0.5 0.0 24.2 0.1 0.5 6.6 0.0 0.2 4.6 0.0 0.5 0.0 2.6 0.0 0.1 0.6 0.2 3.3 0.0 0.0 8.7 1338.5 1.2 2.8 1.1 0.1 0.2 1.7 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.4 0.0 22.8 0.6 0.6 1.5 0.0 0.5 0.6 0.7 0.4 0.1 3.9 2.0 0.3 0.7 0.2 0.3 0.0 0.1 0.1 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 8.6 0.7 0.0 0.0 0.1 0.0 0.0 7.9 0.8 1.0 0.1 0.2 0.5 0.0 10.7 0.3 11.0 0.1 0.8 0.0 0.7 0.0 0.0 9.7 458.3 0.3 0.0 0.3 0.0 0.0 8.5 0.0 0.3 0.6 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 15.2 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 LCAT ENSG00000213398 "Lecithin-cholesterol acyltransferase" P04180 16 67939750-67944131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Hydrolase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 283.0" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 219.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 76.5;Hep G2: 62.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 29.2" HPA044767 Approved Nucleoplasm "Secreted to blood" NA NA 6470000000 6400000000 "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm "HPA044767: AB_2756312" "unprognostic (3.34e-2)" "unprognostic (3.56e-2)" "prognostic unfavorable (8.50e-4)" "unprognostic (5.43e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-1)" "prognostic favorable (4.21e-8)" "unprognostic (6.42e-2)" "unprognostic (4.26e-1)" "unprognostic (4.12e-1)" "unprognostic (1.50e-2)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (9.93e-2)" "unprognostic (1.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.90e-3)" 29.5 20.8 29.3 8.3 29.8 4.2 27.2 56.7 37.5 41.4 37.8 30.6 5.0 28.7 9.1 13.4 26.1 11.5 42.0 28.5 32.3 33.2 283.0 36.1 7.5 41.9 32.7 28.5 17.7 8.0 17.5 17.8 31.6 40.0 4.8 2.8 16.9 18.6 13.2 32.0 17.8 12.3 31.9 23.3 16.5 11.3 33.4 9.4 43.2 8.9 4.4 27.5 27.3 32.0 5.7 9.0 13.0 14.8 11.1 15.6 76.5 21.9 9.3 14.5 10.2 29.5 6.8 3.1 4.0 31.9 5.3 19.4 3.1 30.0 8.9 1.5 7.9 3.9 22.8 62.9 15.2 0.7 10.3 27.1 27.9 30.0 10.4 19.5 10.8 8.7 8.7 1.2 10.5 9.1 3.7 9.5 8.6 1.1 5.0 4.0 14.1 3.3 4.1 9.6 0.5 6.7 33.1 1.6 3.9 26.5 18.6 6.0 20.6 18.5 28.8 20.7 8.1 17.7 5.2 8.3 8.9 2.5 16.5 0.9 0.4 1.9 0.3 0.0 0.4 0.4 0.2 0.3 0.1 0.6 0.4 0.1 1.0 0.4 0.1 0.3 0.0 0.0 29.3 29.8 56.7 37.5 28.5 32.3 41.9 32.7 31.6 31.9 33.4 32.0 16.5 9.6 4.8 27.4 1.1 9.4 4.1 4.6 6.8 0.4 1.9 5.5 7.9 5.7 3.3 3.7 2.1 7.7 1.3 0.1 0.0 1.7 0.2 2.1 6.0 8.0 1.2 14.3 0.1 1.0 3.4 7.3 1.1 1.6 1.3 5.4 10.8 219.5 2.4 0.0 0.1 0.0 4.1 6.6 3.8 1.3 8.7 2.4 7.2 6.5 3.0 7.7 1.0 4.5 1.4 2.1 0.0 8.6 1.9 4.3 0.0 0.4 4.4 0.6 13.1 7.6 10.4 0.9 1.4 0.9 2.6 12.2 1.6 4.1 0.1 1.7 LCMT1 "CGI-68, PPMT1" ENSG00000205629 "Leucine carboxyl methyltransferase 1" Q9UIC8 16 25111731-25178231 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041559, HPA043530" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "HPA041559: AB_2677548, HPA043530: AB_2678532" "unprognostic (9.08e-2)" "prognostic favorable (2.78e-4)" "unprognostic (1.18e-1)" "unprognostic (3.71e-1)" "unprognostic (3.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (1.41e-2)" "unprognostic (7.41e-2)" "unprognostic (4.45e-2)" "unprognostic (4.62e-2)" "unprognostic (1.16e-1)" "prognostic favorable (7.53e-6)" "unprognostic (1.23e-1)" "unprognostic (8.99e-2)" "unprognostic (1.84e-3)" "unprognostic (6.71e-2)" 17.5 27.3 41.5 13.3 43.2 19.9 22.5 41.1 44.5 23.9 36.5 22.0 16.8 21.2 31.1 22.8 20.5 13.6 36.1 45.1 42.8 26.9 10.9 14.9 16.7 39.9 39.0 28.1 47.2 32.0 32.9 24.1 42.4 20.8 21.3 21.8 21.2 21.3 52.3 28.2 17.1 18.5 40.2 16.2 22.5 35.4 43.4 21.3 18.6 36.2 20.2 18.1 20.6 43.0 40.3 36.3 33.9 47.2 30.2 42.9 34.9 24.7 40.5 35.7 45.9 46.4 35.7 24.4 34.1 37.6 44.2 20.1 35.9 34.3 47.9 24.9 53.3 13.5 35.4 77.3 67.9 32.0 20.9 48.7 37.7 39.9 41.4 51.3 32.3 54.0 21.5 31.2 39.5 102.3 37.9 60.6 52.1 25.3 37.0 44.3 30.9 47.7 40.7 27.9 55.5 34.1 29.0 45.8 58.2 39.9 46.0 14.9 19.1 34.6 24.3 23.4 25.0 39.8 43.9 25.8 42.3 27.5 26.6 33.4 36.5 46.2 39.4 33.5 43.3 42.0 47.8 42.1 35.0 31.6 42.8 39.2 14.6 33.6 37.6 18.1 82.9 42.2 41.5 43.2 41.1 44.5 45.1 42.8 39.9 39.0 42.4 40.2 43.4 43.0 21.0 16.0 19.8 15.3 23.5 24.1 31.1 55.6 33.6 25.7 39.3 42.0 34.8 15.7 29.6 33.1 2.1 164.5 20.9 60.5 49.0 51.7 76.5 22.7 31.4 22.7 51.4 29.5 29.0 66.7 69.4 29.1 20.9 20.2 9.5 197.7 23.2 9.5 46.8 23.5 30.1 46.9 38.7 33.9 20.0 137.5 26.1 27.0 33.8 17.8 31.3 32.0 32.0 28.1 31.7 46.7 45.1 24.0 28.9 34.6 79.4 90.0 30.0 26.1 26.3 22.9 67.7 67.3 52.9 35.6 31.8 163.8 29.6 78.7 43.7 34.7 LCN1 "MGC71975, PMFA, TLC, TP, VEGP" ENSG00000160349 "Lipocalin 1" P31025 9 135521438-135526540 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Sensory transduction, Taste, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 12.8;seminal vesicle: 8.0" "Cell type enriched" "Detected in some" 8 "Basal prostatic cells: 8.2" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 3800000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.50e-3)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (3.99e-1)" "unprognostic (1.08e-2)" "unprognostic (1.11e-4)" "unprognostic (1.22e-1)" "unprognostic (7.84e-2)" "unprognostic (9.47e-2)" "unprognostic (3.94e-8)" "unprognostic (2.07e-3)" "unprognostic (3.03e-2)" "unprognostic (5.83e-2)" 0.0 0.0 0.4 0.2 0.4 0.0 0.0 0.4 0.9 0.0 0.4 0.0 0.0 0.0 0.0 12.8 1.9 0.0 0.5 1.1 0.4 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.1 0.0 1.9 0.2 0.4 0.0 0.0 0.0 0.3 8.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.9 1.1 0.4 0.4 0.4 0.4 0.4 0.4 0.6 0.5 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 LCN10 ENSG00000187922 "Lipocalin 10" Q6JVE6 9 136738167-136743356 "Predicted secreted proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 32.3" "Cell type enriched" "Detected in single" 32 "B-cells: 6.4" "Cancer enriched" "Detected in single" 8 "thyroid cancer: 1.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "memory B-cell: 6.5;naive B-cell: 6.4" "Lineage enriched" "Detected in single" 18 "B-cells: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055919 Approved "Secreted in male reproductive system" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 57: B-cells - Immune response" "HPA055919: AB_2682969" "unprognostic (2.02e-1)" "unprognostic (1.35e-2)" "unprognostic (2.62e-1)" "unprognostic (1.89e-1)" "unprognostic (5.85e-2)" "unprognostic (6.54e-3)" "unprognostic (2.22e-4)" "unprognostic (4.54e-2)" "unprognostic (3.97e-1)" "unprognostic (1.31e-1)" "unprognostic (4.14e-3)" "unprognostic (2.96e-1)" "unprognostic (2.77e-2)" "unprognostic (3.11e-2)" "unprognostic (2.52e-1)" "unprognostic (8.32e-2)" "unprognostic (3.86e-1)" 3.5 0.1 1.4 1.0 1.3 0.8 2.8 1.2 2.3 6.1 1.2 1.7 0.1 7.7 32.3 1.2 7.8 0.4 8.2 1.3 1.2 0.1 0.1 0.9 1.3 1.3 1.3 2.1 1.0 0.3 0.1 0.0 1.3 2.7 0.7 0.0 1.6 1.0 0.8 0.7 2.7 3.1 1.2 1.6 2.2 1.2 1.6 0.3 2.1 2.0 1.1 3.2 2.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 6.4 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.3 1.4 1.3 1.2 2.3 1.3 1.2 1.3 1.3 1.3 1.2 1.6 1.3 0.2 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 LCN12 MGC48935 ENSG00000184925 "Lipocalin 12" Q6JVE5 9 136949551-136955497 "Predicted intracellular proteins, Predicted secreted proteins" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "epididymis: 79.5" "Cell type enhanced" "Detected in many" "Astrocytes: 19.6;Collecting duct cells: 49.7;Distal tubular cells: 19.6;Endometrial ciliated cells: 29.8;Glandular and luminal cells: 57.2;Muller glia cells: 27.1" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 44.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 44: Endometrium - Transcription" "unprognostic (7.27e-3)" "unprognostic (5.72e-3)" "unprognostic (2.45e-2)" "unprognostic (7.14e-2)" "unprognostic (4.53e-4)" "unprognostic (9.33e-3)" "unprognostic (1.97e-3)" "unprognostic (1.41e-1)" "unprognostic (1.42e-1)" "unprognostic (3.03e-1)" "unprognostic (7.33e-3)" "unprognostic (2.18e-1)" "unprognostic (5.73e-2)" "unprognostic (5.21e-3)" "unprognostic (3.06e-1)" "unprognostic (5.00e-2)" "unprognostic (7.91e-4)" 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.2 0.8 2.9 0.5 0.1 0.3 0.2 79.5 0.0 3.4 0.0 0.1 0.3 0.3 0.6 1.2 0.0 0.0 1.0 0.4 0.0 0.5 0.6 0.6 0.0 0.2 0.0 0.1 0.1 0.1 1.9 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.1 0.4 0.2 6.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.2 0.8 0.3 0.3 1.0 0.4 0.2 0.4 0.4 0.3 0.1 0.0 2.2 19.6 0.3 0.0 0.4 0.9 0.0 0.3 2.8 1.3 8.0 2.8 2.3 49.7 2.1 0.1 1.7 2.9 19.6 1.2 1.5 29.8 4.3 0.4 16.4 0.0 1.0 1.2 0.0 0.8 0.0 57.2 0.0 6.7 0.0 13.8 0.2 0.0 0.7 4.0 4.1 0.6 0.0 1.0 14.9 0.5 0.0 3.7 0.0 27.1 2.1 1.0 0.2 0.5 1.2 10.9 0.5 0.7 4.4 6.1 1.3 0.9 0.0 0.0 0.2 1.1 0.5 0.0 0.0 0.3 0.5 7.8 5.7 0.3 LCN15 "PRO6093, UNQ2541" ENSG00000177984 "Lipocalin 15" Q6UWW0 9 136759634-136766255 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.9;seminal vesicle: 3.3" "Cell type enriched" "Detected in some" 4 "Enteroendocrine cells: 391.5" "Cancer enriched" "Detected in some" 19 "colorectal cancer: 23.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "Hep G2: 17.7" "Low region specificity" "Detected in all" HPA060584 Enhanced "Secreted in other tissues" NA NA "Cluster 45: Intestine - Brush border" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA060584: AB_2684327" "unprognostic (5.24e-1)" "unprognostic (2.61e-1)" "unprognostic (2.14e-1)" "unprognostic (3.67e-1)" "unprognostic (3.45e-2)" "unprognostic (3.28e-2)" "unprognostic (2.39e-1)" "unprognostic (1.83e-1)" 0.1 0.0 2.3 0.0 2.3 0.0 0.1 2.3 2.7 0.0 2.3 3.0 11.9 0.0 1.4 0.0 0.0 0.0 1.3 2.3 2.3 0.0 0.0 0.0 0.0 2.3 2.3 0.0 0.0 0.0 0.0 0.1 2.3 0.3 1.9 0.0 0.0 3.3 0.6 0.0 3.7 0.0 2.3 0.1 0.0 0.1 2.3 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.3 2.3 2.7 2.3 2.3 2.3 2.3 2.3 2.3 2.3 2.3 1.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.2 0.0 0.6 391.5 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.3 96.9 24.4 0.3 0.4 2.8 0.0 0.1 1.8 0.0 0.0 0.0 0.0 1.0 0.8 0.0 14.7 0.0 0.0 0.2 5.5 0.1 0.0 0.9 0.0 0.3 0.1 0.1 0.4 0.0 0.1 0.0 0.1 0.1 0.9 0.4 LCN2 "24p3, NGAL" ENSG00000148346 "Lipocalin 2" P80188 9 128149071-128153453 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Innate immunity, Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 2768.7;gallbladder: 2223.2;salivary gland: 1308.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 4054.2;Club cells: 5757.0;Ductal cells: 6457.0;Pancreatic endocrine cells: 5424.3;Respiratory ciliated cells: 3161.5;Urothelial cells: 7112.9" "Cancer enhanced" "Detected in many" "stomach cancer: 944.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 88 "basophil: 9.8;neutrophil: 11.9;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 83 "granulocytes: 11.9;monocytes: 4.7" "Group enriched" "Detected in many" 11 "CAPAN-2: 3623.8;EFO-21: 1450.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "cerebellum: 149.7;spinal cord: 102.4" "HPA002695, CAB016549, CAB016550" Enhanced Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 297000000 590000000 "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "CAB016549: , CAB016550: , HPA002695: AB_1852758" "prognostic favorable (9.61e-4)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (7.38e-3)" "unprognostic (1.01e-2)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (4.33e-1)" "unprognostic (1.79e-1)" "unprognostic (2.36e-2)" "unprognostic (2.83e-2)" "unprognostic (1.10e-3)" "unprognostic (6.15e-2)" "unprognostic (2.37e-1)" "unprognostic (3.15e-2)" "unprognostic (1.11e-2)" 4.9 3.6 0.0 125.5 0.1 2768.7 22.0 0.1 0.5 810.5 2.0 249.1 34.4 14.2 20.5 677.6 52.6 2223.2 3.1 0.0 0.1 31.6 67.8 76.1 1.1 0.3 0.1 1.1 74.8 7.3 21.2 2.6 0.3 74.5 131.0 0.0 1308.3 13.5 1.2 28.1 157.3 11.9 0.1 82.0 363.9 0.5 0.1 14.2 27.1 0.3 199.1 669.9 480.7 0.1 117.7 35.1 0.0 4.5 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 3623.8 0.2 1450.9 0.0 3.7 236.4 0.0 6.9 0.1 5.3 0.0 30.4 0.0 0.8 0.2 0.0 1.1 0.1 230.4 0.0 12.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 1.9 80.9 0.2 0.2 0.3 0.3 1.0 20.1 0.1 0.1 2.0 65.3 1.0 0.0 8.4 1.8 0.0 2.9 16.9 0.0 2.9 0.6 4.6 4.7 0.2 0.6 2.1 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 4.7 0.0 0.0 12.1 0.0 0.1 0.1 0.5 0.0 0.1 0.3 0.1 0.3 0.1 0.1 0.1 0.2 0.0 20.8 0.0 15.9 0.3 376.6 4054.2 1.8 0.0 38.1 29.3 0.2 1328.2 5757.0 138.0 0.0 0.8 1.2 315.6 0.0 6457.0 2.0 25.6 4.3 11.5 57.9 11.2 0.0 1837.0 0.3 12.2 237.0 52.3 13.4 0.0 2.2 43.2 0.6 0.0 0.0 264.3 956.2 2.7 0.0 15.8 3.4 34.9 0.0 0.0 60.3 0.0 1.0 0.0 0.0 5424.3 183.4 0.0 1.4 420.6 509.8 1.6 3161.5 0.0 0.0 0.0 337.7 0.0 0.3 51.1 0.0 0.3 7.7 0.0 475.5 7112.9 LCN6 ENSG00000267206 "Lipocalin 6" P62502 9 136744017-136748525 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 60 "epididymis: 1581.7" "Group enriched" "Detected in some" 4 "Adipocytes: 20.2;Endothelial cells: 80.6" "Cancer enriched" "Detected in some" 10 "thyroid cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NB-4: 3.3;REH: 10.7" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.05e-2)" "unprognostic (1.01e-3)" "unprognostic (1.12e-1)" "unprognostic (5.88e-2)" "unprognostic (3.23e-1)" "unprognostic (1.26e-1)" "unprognostic (3.83e-4)" "unprognostic (3.41e-2)" "unprognostic (7.47e-2)" "unprognostic (1.08e-2)" "unprognostic (2.89e-3)" "unprognostic (1.78e-1)" "unprognostic (5.55e-2)" "unprognostic (2.96e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-1)" 10.3 0.3 2.2 1.3 1.9 4.4 9.8 1.7 2.8 11.7 1.7 5.1 0.4 19.1 1581.7 3.3 12.7 2.0 26.3 1.8 1.9 0.9 0.3 3.4 0.9 1.9 2.1 5.6 3.1 0.9 0.5 0.0 2.0 7.6 0.8 0.0 4.5 4.3 2.8 2.2 7.6 5.3 1.8 3.2 7.3 3.9 2.7 0.4 5.2 6.5 0.4 8.3 6.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 1.7 2.8 1.8 1.9 1.9 2.1 2.0 1.8 2.7 1.9 20.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 80.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 5.6 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.4 0.0 0.0 0.0 0.1 6.6 0.1 1.6 0.4 0.5 0.0 0.0 0.0 5.3 0.0 0.0 1.5 LCN8 LCN5 ENSG00000204001 "Lipocalin 8" Q6JVE9 9 136754386-136758543 "Predicted intracellular proteins, Predicted secreted proteins" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 99 "epididymis: 83.7" "Group enriched" "Detected in some" 11 "B-cells: 17.9;Plasma cells: 5.6" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 60 "memory B-cell: 4.1;naive B-cell: 8.1" "Lineage enriched" "Detected in single" 79 "B-cells: 8.1" "Cell line enriched" "Detected in single" 6 "REH: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" "unprognostic (1.64e-2)" "unprognostic (1.00e-1)" "unprognostic (6.71e-2)" "unprognostic (2.11e-2)" "unprognostic (2.92e-1)" "unprognostic (2.89e-1)" "unprognostic (2.00e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 83.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LCN9 ENSG00000148386 "Lipocalin 9" Q8WX39 9 135663322-135666422 "Predicted secreted proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "BEWO: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060941 Enhanced "Secreted in male reproductive system" NA NA "Cluster 28: BEWO - Transcription regulation" "HPA060941: AB_2732654" "unprognostic (7.64e-4)" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.2 0.2 0.2 0.2 0.5 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LCORL "FLJ30696, MLR1" ENSG00000178177 "Ligand dependent nuclear receptor corepressor like" Q8N3X6 4 17841199-18021876 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 133.6;Microglial cells: 135.9;Oligodendrocyte precursor cells: 117.1;Oligodendrocytes: 164.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028794, HPA028795, HPA060033" Uncertain Approved "Nucleoplasm,Nuclear membrane" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear membrane" "HPA028794: AB_10600664, HPA028795: AB_10600882, HPA060033: AB_2684192" "unprognostic (1.06e-1)" "unprognostic (4.95e-2)" "prognostic favorable (9.65e-4)" "unprognostic (3.22e-3)" "unprognostic (3.62e-2)" "unprognostic (2.54e-4)" "unprognostic (8.90e-4)" "unprognostic (3.46e-1)" "unprognostic (3.52e-2)" "unprognostic (7.59e-2)" "unprognostic (2.10e-1)" "unprognostic (1.22e-1)" "unprognostic (7.39e-2)" "unprognostic (1.70e-2)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (7.27e-4)" 2.6 3.7 2.8 3.0 3.6 3.7 2.8 6.4 3.4 2.6 2.1 3.2 5.8 3.0 2.8 2.5 2.0 3.4 1.6 2.3 6.9 4.0 3.4 2.8 3.6 3.4 5.0 4.1 3.3 4.6 1.6 3.9 3.6 2.7 3.6 6.5 2.3 2.1 2.8 4.9 7.0 2.7 3.4 3.4 4.5 5.8 6.3 3.9 3.7 2.9 2.7 2.7 1.9 5.5 5.3 3.4 11.5 5.1 7.1 10.5 2.8 5.9 6.3 5.0 6.7 2.1 7.0 11.4 2.7 3.5 8.8 2.2 4.9 2.2 5.4 1.6 3.7 9.7 5.6 2.4 4.6 7.5 6.7 6.0 2.9 3.3 8.1 7.9 7.1 6.9 5.6 12.1 6.3 1.7 7.3 13.0 5.3 4.1 5.3 7.8 9.1 6.1 7.1 3.0 8.7 10.2 4.8 2.7 3.3 5.2 5.0 4.3 5.8 7.9 4.6 6.7 11.5 12.0 6.2 9.6 6.5 7.9 7.1 7.6 3.3 3.3 2.2 3.5 1.7 2.8 1.3 1.3 2.8 3.5 1.5 2.2 2.5 2.3 3.0 2.3 2.2 1.3 2.8 3.6 6.4 3.4 2.3 6.9 3.4 5.0 3.6 3.4 6.3 5.5 16.9 12.8 15.6 65.6 18.2 23.8 4.4 7.9 17.1 18.4 13.0 9.0 9.4 34.3 9.5 7.3 41.7 8.8 20.9 16.1 9.8 12.3 33.2 14.0 13.1 23.4 35.4 10.1 69.2 10.9 9.0 10.2 14.8 11.8 19.6 26.5 12.8 13.6 16.4 20.2 133.6 23.5 8.2 18.9 29.2 20.1 14.6 23.5 3.6 135.9 21.0 10.4 13.4 117.1 164.2 12.4 16.1 7.5 40.7 10.1 34.1 14.6 15.9 22.5 19.7 13.6 12.8 52.2 16.3 13.6 19.0 9.9 11.6 19.8 16.5 6.3 LDHA ENSG00000134333 "Lactate dehydrogenase A" P00338 11 18394560-18408425 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2198.1;Basal respiratory cells: 2133.0;Extravillous trophoblasts: 2086.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015336, CAB069404" Uncertain Supported Vesicles,Cytosol NA NA 170000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol Vesicles "CAB015336: AB_2134947, CAB069404: " "unprognostic (8.83e-2)" "prognostic unfavorable (2.78e-5)" "unprognostic (3.81e-2)" "unprognostic (1.73e-1)" "unprognostic (3.43e-3)" "unprognostic (4.66e-3)" "prognostic unfavorable (3.26e-8)" "prognostic unfavorable (2.27e-6)" "unprognostic (1.08e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (8.09e-6)" "unprognostic (1.76e-2)" "prognostic unfavorable (9.69e-9)" "unprognostic (4.15e-2)" "unprognostic (1.89e-1)" "unprognostic (3.07e-1)" "unprognostic (1.05e-2)" 444.5 358.1 64.3 139.5 68.4 184.6 330.4 54.0 72.1 203.1 58.4 278.5 158.1 151.1 43.8 450.6 189.2 75.5 361.2 68.4 73.7 440.2 729.2 242.0 97.2 73.6 74.9 149.7 171.5 26.6 95.9 113.9 94.9 170.1 117.4 443.8 267.5 81.8 947.5 468.6 296.6 124.2 58.5 185.3 181.1 95.2 67.4 115.3 180.8 500.3 146.5 266.2 314.4 65.9 1261.4 730.9 28.4 415.2 599.8 399.3 400.6 1186.1 1148.5 936.9 1366.4 324.5 196.6 909.3 380.3 1110.8 727.1 979.2 716.1 1715.1 2082.2 331.3 422.6 329.6 629.4 588.5 148.9 811.2 235.8 411.1 760.3 380.3 373.7 1670.8 550.8 292.3 462.8 431.7 1127.7 319.4 674.8 509.3 182.7 413.2 849.4 432.0 298.0 768.0 1546.6 284.5 220.5 279.3 642.7 518.6 230.8 431.4 241.7 192.9 546.9 1228.3 455.3 1094.7 14.3 348.0 545.1 899.4 1767.1 415.0 434.1 98.4 147.1 79.7 93.8 165.0 105.2 70.4 122.1 99.6 202.1 54.4 78.1 81.0 47.1 91.3 169.3 68.0 140.8 237.6 64.3 68.4 54.0 72.1 68.4 73.7 73.6 74.9 94.9 58.5 67.4 65.9 421.7 73.7 201.6 21.5 220.8 2198.1 475.6 2133.0 523.0 464.2 213.6 229.5 241.8 175.8 837.3 309.0 146.0 509.8 427.2 696.1 434.3 1293.9 204.4 180.0 317.4 492.8 45.6 123.2 38.7 1532.3 2086.2 544.4 163.6 485.8 262.9 205.3 205.6 514.4 659.3 514.8 33.5 285.1 649.0 224.4 1155.1 129.6 287.7 373.9 1177.5 20.6 973.4 444.2 170.0 9.5 12.6 1771.4 590.3 205.0 376.0 546.8 1765.0 682.5 178.1 481.4 190.7 251.6 706.3 195.5 44.0 422.9 1723.2 501.7 410.9 196.2 362.1 530.8 LDHAL6B "LDH6B, LDHAL6, LDHL" ENSG00000171989 "Lactate dehydrogenase A like 6B" Q9BYZ2 15 59206843-59208588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 40.6" "Cell type enriched" "Detected in some" 13 "Spermatocytes: 101.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HeLa: 1.1" "Region enriched" "Detected in single" 6 "olfactory bulb: 1.3" HPA053962 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA053962: AB_2682324" "unprognostic (1.59e-1)" "unprognostic (9.41e-2)" "unprognostic (2.37e-1)" "unprognostic (4.46e-2)" "unprognostic (6.59e-2)" "unprognostic (2.23e-1)" "unprognostic (1.34e-1)" "unprognostic (1.58e-1)" "unprognostic (2.29e-1)" "unprognostic (1.66e-1)" "unprognostic (5.13e-3)" "unprognostic (1.64e-1)" "unprognostic (3.12e-7)" "unprognostic (3.47e-2)" "unprognostic (1.49e-2)" "unprognostic (8.53e-2)" "unprognostic (7.80e-2)" 0.3 0.0 0.2 0.2 0.9 0.0 0.2 0.5 0.9 0.2 2.3 0.2 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.3 0.7 0.2 0.3 0.1 0.1 1.1 0.6 0.0 0.1 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.1 0.0 0.1 0.3 0.3 0.0 0.5 0.0 0.1 40.6 1.0 0.0 0.1 0.0 0.0 0.1 0.2 1.9 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.5 0.9 0.3 0.7 1.1 0.6 1.2 0.5 1.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 101.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LDLR LDLCQ2 ENSG00000130164 "Low density lipoprotein receptor" P01130 19 11089462-11133820 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 112.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 397.4;Alveolar cells type 2: 468.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 46.0" "Lineage enriched" "Detected in many" 9 "granulocytes: 46.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009647, HPA013159" Approved NA NA 23000000 "Cluster 38: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "HPA009647: AB_1079243, HPA013159: AB_1852775" "unprognostic (4.39e-1)" "unprognostic (1.93e-3)" "unprognostic (2.52e-1)" "unprognostic (2.76e-1)" "unprognostic (4.03e-2)" "unprognostic (1.17e-1)" "unprognostic (6.71e-2)" "unprognostic (4.26e-2)" "unprognostic (3.73e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.19e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (1.62e-1)" "unprognostic (2.78e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.43e-4)" 43.6 112.1 6.4 27.3 7.5 27.4 15.6 8.6 13.0 27.5 22.0 20.0 23.6 21.6 3.8 50.1 21.6 36.9 19.3 8.4 10.8 15.2 60.4 54.8 4.8 24.3 14.4 37.7 50.7 10.1 6.9 16.6 20.0 20.2 12.2 2.3 19.1 4.6 3.9 25.5 18.3 28.6 9.9 10.5 36.5 8.4 11.7 4.0 7.7 4.0 5.1 22.6 25.8 14.5 113.6 52.2 61.1 29.9 80.5 152.7 21.0 23.5 89.8 41.3 88.6 52.9 105.3 37.2 94.1 46.1 135.6 88.3 31.1 185.6 19.9 27.5 6.1 18.1 34.5 47.1 120.2 19.2 100.9 192.5 67.5 139.6 30.2 28.5 45.8 29.5 38.9 213.8 31.9 41.4 25.3 25.9 66.4 56.0 67.5 17.1 44.9 48.2 103.1 89.5 14.8 15.4 21.1 45.7 3.8 45.2 19.0 44.6 50.8 36.1 26.3 23.2 44.7 26.8 24.4 23.3 42.8 43.7 83.6 46.0 2.9 0.1 5.4 2.6 1.3 0.6 2.2 1.7 1.6 0.5 2.3 2.2 0.8 2.5 0.8 0.5 1.6 3.2 6.4 7.5 8.6 13.0 8.4 10.8 24.3 14.4 20.0 9.9 11.7 14.5 106.3 397.4 468.6 16.3 8.1 143.4 176.8 182.2 85.4 11.4 144.0 108.7 35.9 92.9 205.7 14.7 6.2 18.4 24.7 273.7 1.9 57.9 1.2 95.3 61.7 75.8 61.9 6.6 10.7 89.0 32.1 42.9 195.2 278.6 75.9 32.9 22.9 149.2 14.9 1.7 8.1 157.2 77.3 16.5 26.5 1.6 19.6 47.4 56.9 7.5 2.7 6.8 8.2 7.5 19.4 86.7 209.7 7.2 30.7 142.7 32.5 0.6 99.1 6.6 6.6 133.4 48.4 4.1 2.8 155.3 197.2 48.2 32.8 214.3 110.7 184.2 LDLRAD2 ENSG00000187942 "Low density lipoprotein receptor class A domain containing 2" Q5SZI1 1 21812265-21825225 "Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.2;Granulosa cells: 4.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 1.2;THP-1: 1.0;TIME: 2.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "basal ganglia: 4.0;midbrain: 5.9" HPA030478 Approved "Secreted - unknown location" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "HPA030478: AB_10601541" "unprognostic (4.16e-2)" "unprognostic (1.22e-1)" "unprognostic (4.13e-2)" "unprognostic (4.21e-2)" "unprognostic (1.78e-1)" "unprognostic (6.22e-3)" "unprognostic (1.35e-2)" "unprognostic (4.85e-2)" "unprognostic (7.52e-2)" "unprognostic (3.80e-2)" "unprognostic (5.34e-2)" "unprognostic (5.38e-2)" "unprognostic (1.04e-3)" "unprognostic (7.39e-3)" "unprognostic (3.14e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" 3.7 2.8 0.4 0.8 0.3 1.0 3.0 0.2 0.1 2.7 0.4 4.3 1.6 3.5 0.0 1.7 2.7 0.5 6.8 0.7 1.1 2.2 0.7 1.6 0.7 2.4 3.3 1.1 2.0 0.0 1.5 0.1 1.7 3.7 0.1 0.0 7.2 0.0 1.2 1.3 2.4 0.1 1.7 2.7 3.7 1.4 1.4 0.0 2.2 0.0 0.3 3.9 2.4 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.5 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.1 0.1 1.2 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 1.0 2.2 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.3 0.2 0.1 0.7 1.1 2.4 3.3 1.7 1.7 1.4 0.3 2.2 0.0 0.6 0.0 0.6 0.5 0.1 0.4 0.6 0.0 0.1 0.1 0.7 0.0 0.2 1.8 0.0 0.2 0.3 0.0 0.0 0.2 1.7 0.3 1.2 1.6 0.0 1.3 0.2 0.0 0.6 1.3 0.0 0.9 0.0 4.9 0.7 0.2 0.3 0.0 0.1 0.0 0.0 0.3 0.2 0.4 0.0 0.3 0.0 1.0 0.5 0.0 0.0 0.0 0.2 0.3 0.1 0.0 1.3 0.5 0.0 0.0 0.8 0.0 0.0 1.2 0.7 0.6 1.2 0.1 0.4 0.3 0.4 0.4 0.0 0.0 LDLRAD4 C18orf1 ENSG00000168675 "Low density lipoprotein receptor class A domain containing 4" O15165 18 13217498-13652755 "Predicted intracellular proteins, Predicted membrane proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.2;lymphoid tissue: 49.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 338.9;Inhibitory neurons: 308.5;Late spermatids: 231.5;Microglial cells: 429.1;Oligodendrocyte precursor cells: 318.7;Oligodendrocytes: 284.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 35.3;JURKAT: 37.4;MOLT-4: 131.3;REH: 31.6;U-698: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047633, HPA065246" Approved Supported Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA047633: , HPA065246: AB_2685444" "unprognostic (2.52e-1)" "unprognostic (4.31e-3)" "unprognostic (5.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.64e-1)" "unprognostic (3.94e-3)" "unprognostic (9.73e-2)" "unprognostic (2.26e-2)" "unprognostic (2.21e-2)" "unprognostic (2.92e-2)" "unprognostic (2.30e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (4.58e-4)" "unprognostic (2.51e-2)" "unprognostic (4.38e-2)" "unprognostic (6.58e-2)" "unprognostic (8.18e-2)" 6.5 4.3 13.9 7.3 38.0 9.7 6.3 34.6 25.9 7.8 37.4 5.8 6.1 12.4 0.9 3.9 11.3 4.6 16.6 10.7 16.4 4.0 10.3 4.6 6.5 46.1 33.2 2.3 3.3 2.9 6.9 6.2 38.6 8.6 2.1 7.0 3.0 5.3 15.4 4.2 7.2 5.7 27.3 5.6 5.0 9.2 48.2 49.3 4.4 9.5 3.8 5.3 5.3 39.6 0.2 0.3 1.4 0.8 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.1 2.7 1.6 0.8 0.4 0.0 0.0 0.0 17.1 1.7 35.3 7.0 1.2 0.0 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.4 37.4 0.4 0.7 0.0 2.6 131.3 1.1 2.9 0.3 8.9 31.6 0.1 1.2 0.0 1.1 2.4 3.9 0.5 2.2 0.0 1.9 3.8 4.7 2.4 1.3 11.5 0.2 1.9 5.6 0.4 26.1 0.0 6.9 6.4 12.8 7.0 2.1 6.5 7.7 5.7 5.2 5.8 5.6 3.9 4.4 8.2 7.6 12.1 9.1 8.5 5.9 3.4 4.5 13.9 38.0 34.6 25.9 10.7 16.4 46.1 33.2 38.6 27.3 48.2 39.6 19.4 3.2 4.7 143.3 79.2 10.5 2.7 0.8 0.0 5.4 26.0 16.9 18.4 0.0 5.0 1.8 70.9 0.6 21.0 6.8 1.9 5.1 135.2 16.3 22.0 16.6 58.7 7.6 338.9 3.6 0.7 16.5 13.3 7.8 23.5 7.6 25.0 24.4 21.1 0.0 308.5 9.1 2.0 27.4 160.5 231.5 11.1 56.2 14.2 429.1 13.6 4.7 3.1 318.7 284.9 0.7 2.6 24.5 11.7 13.5 15.6 2.3 13.7 18.7 6.6 2.3 9.7 5.4 4.9 0.4 7.7 1.6 66.0 0.2 8.8 3.2 LEAP2 LEAP-2 ENSG00000164406 "Liver enriched antimicrobial peptide 2" Q969E1 5 132873444-132875046 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 532.0" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 1650.6" "Cancer enriched" "Detected in many" 17 "liver cancer: 40.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 3.4;Hep G2: 4.7;U-266/84: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 790000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (2.14e-2)" "unprognostic (8.78e-2)" "unprognostic (4.75e-1)" "unprognostic (2.16e-1)" "unprognostic (2.82e-1)" "unprognostic (1.06e-2)" "unprognostic (2.78e-3)" "unprognostic (6.53e-2)" "unprognostic (3.86e-2)" "unprognostic (1.62e-1)" "unprognostic (7.08e-3)" "unprognostic (2.91e-2)" "unprognostic (1.02e-1)" "unprognostic (2.39e-1)" "unprognostic (3.97e-1)" "unprognostic (1.11e-1)" "prognostic favorable (2.68e-4)" 0.9 0.9 0.9 0.3 0.8 0.5 1.0 2.3 1.2 1.3 0.4 1.7 12.3 0.8 0.2 1.3 1.2 4.5 1.2 0.8 0.8 11.9 532.0 1.1 0.5 0.8 0.7 1.2 1.9 0.7 1.1 0.2 1.0 2.4 1.6 1.0 1.3 0.2 1.4 1.4 23.4 0.1 0.6 2.2 2.0 1.1 0.8 0.3 1.9 0.5 0.5 7.8 1.6 1.8 0.1 0.7 0.4 1.5 0.6 0.4 0.4 0.1 0.1 0.4 0.6 3.4 0.5 0.2 0.1 0.1 0.4 0.7 1.4 0.6 0.0 1.2 1.0 0.3 1.2 4.7 0.1 0.5 0.2 0.1 0.5 0.0 0.1 0.3 0.1 1.1 0.5 0.4 0.0 0.3 0.8 0.6 1.1 1.1 0.5 0.0 0.2 1.1 0.0 0.2 0.5 0.3 0.3 0.7 0.5 0.4 0.8 0.4 0.0 0.2 0.3 0.6 0.1 1.1 3.8 1.1 0.0 0.7 0.2 1.3 0.7 0.3 0.6 0.4 0.8 1.0 0.6 0.7 0.6 0.8 1.0 0.8 1.7 1.0 0.3 0.8 1.1 0.3 0.9 0.8 2.3 1.2 0.8 0.8 0.8 0.7 1.0 0.6 0.8 1.8 2.5 0.0 2.6 1.3 7.9 10.1 10.8 4.1 2.8 17.1 4.9 2.8 1.9 64.3 2.6 0.0 33.3 3.3 7.6 39.2 9.8 2.9 6.2 4.8 3.8 5.2 4.8 9.3 1.1 9.8 7.9 5.8 1.5 10.3 7.0 6.7 14.3 1650.6 1.4 13.5 1.4 12.1 0.0 17.3 14.1 0.5 1.5 4.2 5.4 1.0 2.2 5.2 13.4 2.0 1.8 2.9 30.9 1.9 3.1 14.0 279.9 51.8 1.7 25.2 0.0 13.5 4.8 7.0 2.9 1.4 7.7 7.3 6.2 4.1 8.0 10.2 LECT2 "chm-II, chm2" ENSG00000145826 "Leukocyte cell derived chemotaxin 2" O14960 5 135922279-135954983 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "liver: 477.9" "Group enriched" "Detected in some" 15 "Early spermatids: 147.7;Hepatocytes: 100.7;Late spermatids: 55.8" "Cancer enriched" "Detected in single" 216 "liver cancer: 35.1" "Region enhanced" "Detected in some" "cerebellum: 6.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA043883, HPA058246" Enhanced Supported Vesicles,Cytosol "Secreted to blood" NA NA 26500000 5300000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 20: HeLa - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Vesicles "HPA043883: AB_2678714, HPA058246: " "prognostic favorable (4.16e-5)" "unprognostic (2.57e-2)" "unprognostic (3.52e-1)" 0.2 0.5 0.4 0.4 0.8 2.4 0.4 6.3 2.8 0.1 0.0 0.2 0.5 0.3 0.8 0.4 0.1 0.4 0.1 0.9 0.0 0.6 477.9 0.3 0.9 0.0 0.0 0.3 0.1 0.2 0.0 0.2 0.1 0.4 0.2 3.1 0.7 0.2 2.1 1.4 0.9 0.1 0.0 0.9 0.3 8.8 0.0 0.2 0.4 0.0 0.2 0.1 0.0 1.1 0.3 0.4 0.5 0.7 0.2 0.4 0.6 0.1 0.0 0.0 0.0 0.1 0.4 0.8 0.6 0.3 0.3 0.5 0.0 0.2 0.0 0.3 1.0 0.7 0.7 1.3 0.3 1.0 0.1 0.2 0.1 0.3 0.3 0.6 0.1 0.8 0.2 0.3 0.6 0.0 0.4 0.4 0.5 0.3 0.6 0.5 0.5 0.2 0.2 0.9 0.3 0.6 0.0 0.2 0.0 0.9 0.1 0.5 0.8 0.3 0.4 0.4 0.1 1.1 0.5 0.3 0.3 0.9 0.8 0.6 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.4 0.8 6.3 2.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 147.7 0.0 0.1 0.3 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 100.7 0.0 0.0 0.1 0.0 0.0 2.9 0.0 55.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 6.6 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 LEFTY1 "LEFTB, LEFTYB" ENSG00000243709 "Left-right determination factor 1" O75610 1 225886282-225911382 "Metabolic proteins, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "intestine: 68.3;pancreas: 96.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 201.5;Glandular and luminal cells: 175.0;Intestinal goblet cells: 86.1;Paneth cells: 228.9;Undifferentiated cells: 301.0" "Group enriched" "Detected in many" 4 "colorectal cancer: 44.8;endometrial cancer: 36.2;pancreatic cancer: 13.8;testis cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 51 "basophil: 17.0" "Lineage enriched" "Detected in single" 51 "granulocytes: 17.0" "Cell line enriched" "Detected in some" 6 "NTERA-2: 50.2" "HPA047883, HPA056210" Approved "Secreted in other tissues" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 5: NTERA-2 - Transcription" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047883: AB_2680200, HPA056210: AB_2683067" "unprognostic (2.81e-1)" "unprognostic (2.31e-1)" "unprognostic (7.26e-2)" "unprognostic (1.18e-2)" "unprognostic (1.83e-2)" "unprognostic (3.50e-2)" "unprognostic (1.52e-2)" "unprognostic (4.60e-2)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (7.76e-2)" "unprognostic (6.13e-2)" "prognostic unfavorable (2.48e-6)" "unprognostic (2.78e-2)" "unprognostic (1.12e-1)" "unprognostic (2.01e-1)" "unprognostic (2.61e-2)" 0.3 0.2 2.1 7.8 2.1 0.0 0.4 1.8 2.7 1.4 1.3 68.3 0.2 0.5 6.9 0.1 0.6 0.0 0.4 2.1 1.9 1.7 0.9 0.3 0.0 1.6 1.7 4.1 96.9 0.0 1.0 0.2 1.7 0.9 32.4 0.8 1.5 3.3 0.4 0.2 2.9 0.8 1.6 0.3 1.4 0.8 1.9 0.0 0.1 0.1 0.1 1.5 0.2 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.1 0.3 0.0 0.0 0.0 4.5 0.1 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.2 0.0 0.0 0.0 5.4 0.6 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 2.1 2.1 1.8 2.7 2.1 1.9 1.6 1.7 1.7 1.6 1.9 1.9 0.2 0.0 0.0 0.7 1.0 0.4 1.6 0.0 0.0 1.8 0.2 0.3 0.1 14.3 0.0 0.0 0.0 0.0 0.0 51.7 1.9 20.1 1.8 201.5 9.9 0.3 31.5 0.0 2.3 29.6 0.1 1.6 0.0 175.0 0.0 1.6 0.0 0.2 0.0 0.0 2.3 86.1 0.0 0.0 0.0 3.9 1.5 2.1 0.0 0.0 0.0 0.9 0.0 1.5 0.2 0.5 228.9 1.9 0.0 0.8 0.7 6.0 0.0 1.4 0.0 0.0 0.6 2.5 4.2 0.0 0.0 0.0 1.0 1.3 301.0 1.3 LEFTY2 "EBAF, LEFTA, LEFTYA, TGFB4" ENSG00000143768 "Left-right determination factor 2" O00292 1 225936598-225941383 "Disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 74.5;endometrium 1: 170.0" "Cell type enhanced" "Detected in some" "Early spermatids: 17.4;Endometrial stromal cells: 30.8;Granulosa cells: 43.6;Late spermatids: 34.6;Leydig cells: 18.0;Peritubular cells: 12.0" "Cancer enriched" "Detected in many" 8 "testis cancer: 41.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 10.6;NTERA-2: 44.4;RPMI-8226: 50.9;SuSa: 25.5" "CAB025801, HPA047883, HPA056210" Approved "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "CAB025801: , HPA047883: AB_2680200, HPA056210: AB_2683067" "unprognostic (3.78e-2)" "unprognostic (4.10e-3)" "unprognostic (5.79e-3)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (2.30e-1)" "unprognostic (1.52e-1)" "unprognostic (4.87e-2)" "unprognostic (9.75e-4)" "unprognostic (2.91e-1)" "unprognostic (3.84e-1)" "unprognostic (7.98e-2)" "unprognostic (9.14e-3)" "unprognostic (1.15e-1)" "unprognostic (4.69e-2)" "unprognostic (1.90e-4)" "unprognostic (1.64e-3)" 1.8 1.4 0.2 1.1 0.3 0.0 0.7 0.3 0.3 74.5 15.9 1.2 0.3 170.0 12.1 0.1 3.6 0.4 2.6 0.7 0.2 0.4 0.0 2.4 0.2 0.2 0.3 37.8 0.3 0.0 16.0 3.5 0.2 1.5 0.2 0.9 0.1 12.4 0.7 0.3 0.4 36.9 0.2 0.7 0.3 4.5 0.8 0.2 0.1 0.8 0.0 0.5 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 44.4 0.0 0.0 0.0 0.0 50.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 2.6 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.7 0.2 0.2 0.3 0.2 0.2 0.8 0.3 0.6 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.4 17.4 2.2 30.8 0.6 0.0 0.0 0.0 0.0 0.6 1.4 0.0 0.7 0.0 43.6 0.4 0.0 0.5 0.0 0.1 0.2 0.0 0.0 0.2 34.6 18.0 0.3 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 12.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.3 1.7 6.7 0.4 0.0 0.0 0.0 0.2 0.7 0.0 0.1 LENG8 "KIAA1932, MGC40108, pp13842" ENSG00000167615 "Leukocyte receptor cluster member 8" Q96PV6 19 54448887-54462016 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Rod photoreceptor cells: 598.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 479.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042004, HPA061571" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA042004: AB_10794642, HPA061571: AB_2684562" "unprognostic (2.09e-2)" "unprognostic (3.24e-3)" "unprognostic (5.14e-3)" "unprognostic (2.19e-1)" "unprognostic (4.42e-2)" "prognostic favorable (7.59e-4)" "unprognostic (1.38e-2)" "unprognostic (1.77e-1)" "unprognostic (1.92e-2)" "unprognostic (4.45e-3)" "unprognostic (5.11e-3)" "unprognostic (8.85e-3)" "prognostic unfavorable (3.30e-7)" "unprognostic (3.64e-2)" "unprognostic (6.92e-2)" "unprognostic (1.71e-1)" "prognostic favorable (2.73e-6)" 238.9 243.5 53.8 84.3 62.0 79.5 264.9 62.5 94.5 327.4 75.3 317.4 112.6 318.2 40.6 199.0 384.3 25.5 237.5 53.1 75.5 299.0 193.2 293.0 70.8 60.3 53.1 425.1 545.6 15.7 380.6 30.9 59.0 353.6 28.9 223.7 267.0 28.0 134.2 249.1 336.3 41.1 38.1 386.8 300.0 238.5 69.7 38.3 374.8 10.3 34.5 283.9 279.8 90.7 70.5 57.6 68.0 37.1 20.7 33.6 37.8 58.1 8.9 11.2 21.7 45.3 100.8 55.9 24.6 46.5 2.7 91.0 21.7 27.0 8.2 93.9 479.3 84.0 179.4 32.0 24.4 12.9 68.5 74.9 39.5 6.7 26.4 91.4 17.2 42.6 66.7 84.1 14.0 24.6 53.1 66.8 17.6 17.5 11.9 84.3 20.5 78.6 27.1 19.4 54.4 29.9 6.3 42.7 15.1 34.1 42.7 18.1 81.7 47.2 48.3 7.6 63.0 77.7 38.4 25.7 40.7 89.9 32.4 3.2 1.0 1.4 0.8 0.7 0.9 0.7 0.5 0.9 0.6 2.5 0.8 0.7 4.5 0.9 0.5 3.1 0.9 0.4 53.8 62.0 62.5 94.5 53.1 75.5 60.3 53.1 59.0 38.1 69.7 90.7 46.7 19.2 30.7 77.1 50.2 28.8 21.3 26.4 35.9 122.7 57.2 47.1 2.2 44.3 35.7 40.5 112.6 20.2 57.5 73.5 1.9 18.5 35.4 52.4 33.8 32.5 105.0 43.3 62.8 31.6 11.9 35.3 128.4 64.8 11.4 67.4 35.3 39.2 25.3 95.9 53.4 84.9 42.7 48.2 28.0 12.4 43.5 59.6 24.9 52.5 45.9 36.1 25.7 64.3 86.5 30.8 52.2 36.9 48.2 39.9 74.2 9.8 68.9 598.6 19.7 25.6 44.3 23.7 13.9 40.5 38.5 21.1 37.6 45.7 59.5 43.1 LEP "OB, OBS" ENSG00000174697 Leptin P41159 7 128241278-128257629 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "adipose tissue: 307.5;breast: 90.1" "Group enriched" "Detected in some" 44 "Extravillous trophoblasts: 124.2;Syncytiotrophoblasts: 432.2" "Cancer enhanced" "Detected in some" "breast cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.1;SuSa: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" CAB010490 Approved "Secreted to blood" NA NA 17000000 19000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB010490: AB_2296951" "unprognostic (8.19e-3)" "unprognostic (5.33e-1)" "unprognostic (1.60e-4)" "unprognostic (1.19e-1)" "unprognostic (7.99e-3)" "unprognostic (1.83e-1)" "unprognostic (6.56e-3)" "unprognostic (1.98e-2)" "unprognostic (1.42e-2)" "unprognostic (2.45e-2)" "unprognostic (2.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.23e-2)" "unprognostic (6.84e-2)" 307.5 0.8 0.1 5.0 0.1 0.1 90.1 0.5 0.3 0.1 0.1 2.0 0.1 0.0 0.0 0.2 0.1 1.2 1.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 2.4 0.0 0.0 4.6 0.1 0.0 0.4 0.0 1.1 0.0 0.7 3.9 1.2 0.1 0.0 0.2 0.5 0.2 0.1 0.3 0.2 1.2 0.0 1.0 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.8 0.1 0.6 0.3 0.0 0.2 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 124.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.1 432.2 0.1 0.1 0.0 0.1 LFNG SCDO3 ENSG00000106003 "LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q8NES3 7 2512529-2529177 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 74.4" "Cell type enhanced" "Detected in many" "dendritic cells: 40.3;Enteroendocrine cells: 87.4;monocytes: 38.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 37.7;OE19: 46.4;RH-30: 46.0;U-2 OS: 49.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069130 Approved Approved "Nuclear membrane,Golgi apparatus" "Intracellular and membrane" NA NA 880000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "Nuclear membrane" "HPA069130: AB_2686091" "unprognostic (4.58e-2)" "unprognostic (1.17e-2)" "unprognostic (2.52e-2)" "prognostic favorable (6.36e-4)" "unprognostic (1.85e-2)" "unprognostic (8.34e-2)" "unprognostic (4.15e-1)" "unprognostic (7.86e-2)" "unprognostic (1.91e-1)" "unprognostic (2.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.89e-1)" "unprognostic (5.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.09e-1)" "unprognostic (1.97e-2)" "unprognostic (2.28e-2)" 16.7 6.5 23.3 17.3 25.9 9.8 13.7 29.3 22.4 9.9 11.1 23.1 15.5 9.4 2.2 11.4 6.1 11.8 13.1 17.4 30.1 9.0 2.5 14.4 18.6 34.1 35.6 1.8 74.4 3.0 3.7 6.5 24.8 17.1 12.0 3.0 33.4 4.6 4.6 58.2 17.2 5.8 25.0 20.9 37.8 4.2 38.1 5.8 6.7 3.6 10.8 12.2 13.8 23.6 1.5 14.3 18.4 2.5 2.0 1.7 1.2 5.4 2.8 4.7 5.9 6.0 37.7 1.1 16.7 14.8 8.1 27.1 2.9 5.1 2.3 8.6 0.6 4.3 7.7 3.2 0.1 6.2 7.7 3.3 12.6 7.8 0.8 3.2 1.9 0.3 0.7 0.2 3.6 34.5 0.1 8.7 22.4 46.4 10.3 1.8 46.0 2.9 1.8 4.5 16.9 4.2 6.2 1.4 0.3 4.7 10.2 7.3 4.5 10.5 49.7 0.4 15.4 0.2 0.0 1.4 11.8 16.4 2.0 6.3 5.3 12.7 1.8 6.9 2.0 1.1 1.7 0.9 2.3 2.0 1.8 1.8 2.8 1.3 6.6 0.6 4.2 1.7 23.3 25.9 29.3 22.4 17.4 30.1 34.1 35.6 24.8 25.0 38.1 23.6 23.3 6.4 6.0 18.9 15.6 6.8 2.5 10.6 3.4 8.5 5.3 12.4 3.6 5.7 2.8 0.0 0.0 0.1 40.3 23.1 0.0 1.2 0.1 2.4 8.5 16.0 87.4 2.7 0.0 6.4 0.3 5.7 30.5 1.2 17.7 0.1 13.9 0.6 7.0 0.0 0.1 34.5 6.1 30.4 13.8 0.5 1.8 30.6 3.6 11.2 38.2 31.3 19.6 1.5 0.1 21.7 3.1 0.0 12.6 2.2 8.8 0.4 1.2 0.8 0.0 0.6 5.0 0.3 3.1 0.6 4.0 0.0 15.9 0.5 15.3 0.7 LGALS3BP "90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B" ENSG00000108679 "Galectin 3 binding protein" Q08380 17 78971238-78979947 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 629.8;Paneth cells: 584.1;Proximal enterocytes: 931.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "monocytes: 27.2;T-cells: 68.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 862.9;SK-BR-3: 2270.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000410, HPA000554" Uncertain "Secreted to blood" NA NA 7100000000 "Cluster 32: T-cells - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA000410: , HPA000554: AB_1079246" "unprognostic (1.23e-2)" "unprognostic (1.40e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.63e-3)" "unprognostic (1.62e-2)" "unprognostic (1.68e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (1.57e-2)" "unprognostic (4.55e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (1.58e-1)" "unprognostic (1.65e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" 192.8 218.6 51.2 75.0 91.4 48.6 109.5 95.6 62.3 188.8 159.8 210.8 312.9 121.4 45.2 114.2 155.6 240.8 311.4 46.6 81.4 103.1 68.5 182.8 52.7 145.6 88.3 155.6 79.1 107.8 134.9 147.0 116.8 114.3 92.6 10.0 498.7 154.2 20.0 54.0 260.9 80.2 104.3 76.8 315.6 70.1 89.8 48.8 102.0 20.4 25.3 125.0 119.0 152.5 499.0 255.3 7.2 11.2 157.3 181.4 147.9 55.7 49.0 371.3 725.7 107.5 862.9 2.8 372.7 33.5 361.7 200.1 53.6 203.7 11.5 1.2 319.0 33.8 206.0 481.0 387.7 0.4 31.6 305.8 111.5 197.5 12.6 83.8 9.9 68.7 3.4 1.5 87.7 62.8 151.2 6.0 13.0 163.7 170.7 100.1 209.9 4.8 155.5 352.6 235.1 267.4 52.7 2270.3 754.5 14.0 57.5 16.1 16.3 245.5 169.8 7.1 225.8 0.8 2.2 3.7 332.1 96.8 263.7 0.8 17.7 4.9 12.0 27.2 25.0 4.7 43.3 17.9 7.6 2.4 68.4 33.0 1.2 9.4 14.7 0.6 26.0 25.1 51.2 91.4 95.6 62.3 46.6 81.4 145.6 88.3 116.8 104.3 89.8 152.5 88.0 189.1 144.3 9.8 5.6 31.1 146.8 462.5 60.3 37.2 60.5 43.1 180.7 127.2 306.2 139.8 6.2 179.1 3.4 629.8 17.6 275.0 7.2 77.4 118.7 26.8 168.2 4.4 0.3 136.5 336.0 284.6 257.9 126.9 13.3 316.5 46.8 45.8 88.3 74.0 5.3 328.7 309.3 36.8 23.7 37.1 282.7 36.0 81.8 8.4 27.9 80.8 2.1 11.6 33.9 132.4 584.1 266.3 3.5 72.4 931.4 49.2 123.9 24.3 177.5 80.5 119.6 4.5 2.1 83.8 27.3 108.9 15.4 228.3 400.5 128.2 LGI1 "EPITEMPIN, EPT, ETL1, IB1099" ENSG00000108231 "Leucine rich glioma inactivated 1" O95970 10 93757840-93806272 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 39.7;choroid plexus: 44.7" "Cell type enhanced" "Detected in some" "Astrocytes: 242.9;Excitatory neurons: 57.1;Inhibitory neurons: 74.7;Oligodendrocyte precursor cells: 28.6" "Group enriched" "Detected in some" 7 "glioma: 1.8;testis cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.4;CACO-2: 2.0;NTERA-2: 6.1;SuSa: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (1.26e-1)" "unprognostic (4.68e-2)" "unprognostic (2.45e-2)" "unprognostic (1.01e-1)" "unprognostic (8.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.24e-3)" "unprognostic (1.85e-1)" "unprognostic (4.07e-3)" "unprognostic (8.71e-2)" "unprognostic (2.21e-1)" "unprognostic (5.93e-2)" "unprognostic (4.65e-1)" 0.5 1.8 26.8 0.1 31.5 0.0 0.2 23.8 39.7 0.1 44.7 4.0 0.5 0.1 0.0 4.3 0.1 1.0 0.5 29.2 22.6 0.0 2.7 0.0 0.0 29.9 24.2 0.0 0.2 0.0 7.6 0.0 32.9 0.7 2.6 0.4 0.1 0.5 5.9 0.3 1.5 0.6 23.7 0.0 1.8 0.4 26.7 0.0 0.2 3.6 0.1 0.9 0.3 25.2 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 31.5 23.8 39.7 29.2 22.6 29.9 24.2 32.9 23.7 26.7 25.2 0.2 0.0 0.0 242.9 0.0 0.3 0.4 0.0 0.0 0.5 0.4 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.4 0.0 0.0 57.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 6.0 0.0 0.0 74.7 0.0 0.0 0.0 0.4 1.6 1.5 0.0 0.0 10.3 0.0 0.1 0.0 28.6 3.9 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.5 0.6 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.2 LGI2 "FLJ10675, KIAA1916" ENSG00000153012 "Leucine rich repeat LGI family member 2" Q8N0V4 4 24998847-25030946 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "parathyroid gland: 127.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.5;Inhibitory neurons: 33.3;Oligodendrocyte precursor cells: 10.1;Skeletal myocytes: 8.6;Smooth muscle cells: 8.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 28.2;HAP1: 5.2;RPMI-8226: 13.3;SCLC-21H: 18.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017140 Approved Uncertain Centrosome "Secreted to blood" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Centrosome "HPA017140: AB_1852833" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (4.31e-2)" "unprognostic (1.20e-5)" "unprognostic (3.99e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-2)" "unprognostic (8.54e-2)" "unprognostic (1.03e-1)" "unprognostic (1.29e-1)" "unprognostic (3.47e-2)" "unprognostic (1.62e-1)" "unprognostic (9.38e-5)" "unprognostic (5.78e-2)" "unprognostic (1.61e-1)" "unprognostic (2.06e-4)" "unprognostic (5.03e-3)" 3.4 1.6 2.7 7.5 3.5 0.0 0.8 5.7 4.1 1.5 1.0 3.1 0.7 6.7 2.7 1.4 7.8 7.1 3.3 1.9 9.2 4.3 0.3 1.0 2.9 12.0 13.1 2.1 1.7 127.8 0.3 3.9 6.7 0.5 1.6 2.3 0.3 1.2 0.2 0.3 1.8 13.6 4.0 0.9 1.4 0.7 4.2 2.3 1.1 0.4 8.4 3.0 0.7 3.3 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.8 0.0 0.2 0.0 5.2 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 4.6 0.0 1.0 0.0 1.2 13.3 0.5 0.0 18.2 0.0 0.0 0.0 0.0 2.9 0.0 0.4 0.0 0.3 2.0 0.0 0.8 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.5 5.7 4.1 1.9 9.2 12.0 13.1 6.7 4.0 4.2 3.3 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.1 0.0 0.0 3.7 0.0 0.0 5.5 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.1 2.0 2.1 0.0 0.0 3.0 0.0 0.0 1.0 0.0 0.1 0.0 0.1 0.7 0.0 4.8 1.7 33.3 0.0 0.0 0.6 0.5 0.1 0.6 1.0 0.0 2.8 0.0 0.5 0.0 10.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 8.6 8.5 0.0 0.4 0.0 0.1 0.3 0.0 0.1 0.0 0.1 LGI3 ENSG00000168481 "Leucine rich repeat LGI family member 3" Q8N145 8 22146830-22157084 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 112.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 22.2;Excitatory neurons: 17.7;Inhibitory neurons: 23.7;Melanocytes: 40.9;Oligodendrocytes: 58.4" "Group enriched" "Detected in many" 5 "glioma: 4.7;melanoma: 14.3;thyroid cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.1;SCLC-21H: 1.6;SK-MEL-30: 1.6;WM-115: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024826 Approved Cytosol "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA024826: AB_10601131" "unprognostic (4.41e-2)" "unprognostic (1.78e-1)" "unprognostic (3.28e-1)" "unprognostic (8.11e-3)" "unprognostic (1.14e-1)" "unprognostic (7.45e-2)" "unprognostic (3.38e-1)" "unprognostic (2.43e-2)" "unprognostic (9.64e-2)" "unprognostic (1.64e-2)" "unprognostic (6.25e-3)" "unprognostic (1.26e-2)" "unprognostic (5.59e-5)" "unprognostic (1.36e-2)" "unprognostic (9.41e-2)" "unprognostic (4.80e-2)" "unprognostic (4.14e-2)" 0.3 3.4 44.2 0.1 79.7 0.1 0.2 81.1 84.6 2.9 5.2 0.8 0.3 1.2 0.3 6.5 1.6 0.1 2.2 43.4 70.4 0.4 0.1 15.9 0.0 85.8 72.4 0.2 0.8 0.3 2.8 0.0 90.7 1.3 0.1 3.9 1.7 2.8 0.2 15.0 0.5 0.6 57.1 0.1 0.9 0.8 86.3 0.3 13.0 0.1 0.3 0.2 2.5 112.6 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.6 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.2 79.7 81.1 84.6 43.4 70.4 85.8 72.4 90.7 57.1 86.3 112.6 0.0 0.0 22.2 2.0 0.0 2.3 0.0 0.0 0.0 2.7 0.1 0.0 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.8 0.0 17.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.4 0.0 0.3 0.1 40.9 2.8 0.0 1.2 0.0 6.6 58.4 0.1 0.0 7.2 0.0 0.0 0.0 0.8 0.0 2.9 0.0 0.0 0.6 0.1 0.1 1.4 0.6 0.0 0.0 0.9 0.0 0.0 LGI4 ENSG00000153902 "Leucine rich repeat LGI family member 4" Q8N135 19 35124513-35142451 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 74.7;Distal enterocytes: 33.1;Muller glia cells: 95.5;Sertoli cells: 78.9;Smooth muscle cells: 104.4" "Group enriched" "Detected in many" 6 "glioma: 4.5;melanoma: 11.5;renal cancer: 13.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 27 "WM-115: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042116, HPA043556" Approved Approved "Golgi apparatus" "Secreted in brain" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA042116: AB_2677855, HPA043556: AB_2678550" "unprognostic (3.79e-1)" "unprognostic (6.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-2)" "unprognostic (3.71e-2)" "unprognostic (2.12e-2)" "unprognostic (4.26e-2)" "unprognostic (4.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-1)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.84e-7)" "unprognostic (1.71e-2)" "unprognostic (4.47e-1)" "unprognostic (7.73e-2)" "unprognostic (7.13e-2)" 77.6 5.4 71.2 4.1 72.3 0.2 36.1 70.3 98.4 99.9 52.1 100.5 3.6 35.5 2.3 15.0 43.7 5.0 39.4 67.8 61.3 4.7 8.0 14.3 2.1 86.5 68.4 13.3 6.4 1.4 4.4 3.6 70.1 37.2 3.7 7.2 12.2 13.3 39.1 21.2 35.1 4.8 72.8 1.9 27.0 2.7 72.0 0.5 19.1 5.4 0.5 33.5 79.3 81.4 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.1 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 71.2 72.3 70.3 98.4 67.8 61.3 86.5 68.4 70.1 72.8 72.0 81.4 13.3 0.0 0.0 74.7 0.2 2.5 0.6 0.3 3.4 0.8 1.5 1.5 17.1 0.0 0.8 1.8 2.1 0.0 0.2 33.1 0.0 0.0 0.1 0.2 2.8 5.4 1.8 0.0 21.9 0.0 0.3 12.7 0.0 0.2 0.0 0.0 7.9 2.0 0.1 0.0 2.2 0.9 0.0 0.0 4.6 0.3 14.6 0.7 10.6 5.6 0.1 95.5 0.0 2.0 9.2 0.1 21.8 7.2 0.3 1.2 1.1 0.1 0.9 3.1 78.9 7.9 104.4 2.8 2.8 0.8 2.4 0.0 0.7 0.0 0.7 1.1 LGMN "LGMN1, PRSC1" ENSG00000100600 Legumain Q99538 14 92703807-92748679 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 1448.9;Macrophages: 346.1;Syncytiotrophoblasts: 416.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 209.2" "Lineage enriched" "Detected in all" 12 "dendritic cells: 209.2" "Cell line enhanced" "Detected in many" "RPMI-8226: 898.6;U-266/70: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001426 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001426: AB_1079247" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (3.50e-2)" "unprognostic (4.70e-2)" "unprognostic (2.47e-1)" "prognostic favorable (4.70e-4)" "unprognostic (8.06e-2)" "unprognostic (3.64e-2)" "unprognostic (7.18e-3)" "unprognostic (7.24e-2)" 173.7 44.4 37.6 82.2 38.6 20.6 69.7 31.7 60.8 52.6 51.2 102.5 110.4 30.8 36.8 64.5 36.6 145.8 85.3 40.0 40.3 205.9 111.1 107.3 177.0 35.6 37.3 33.0 37.9 247.0 24.9 262.1 42.4 51.9 105.9 19.7 56.4 32.2 50.4 32.7 97.6 65.0 35.9 202.2 107.0 29.8 62.8 52.8 93.2 50.4 54.9 144.7 52.1 49.4 33.2 47.5 30.8 57.4 94.3 76.0 108.4 70.3 67.0 71.7 84.2 36.9 58.6 18.2 101.5 116.5 44.3 81.5 0.0 60.8 33.7 1.6 36.2 1.2 24.4 42.8 27.7 1.0 2.7 54.2 29.1 68.4 39.4 21.3 82.1 33.7 7.4 150.9 5.2 45.2 8.9 1.2 15.1 208.2 32.1 8.4 27.1 898.6 59.2 129.1 33.6 23.2 97.9 59.4 53.0 66.8 43.9 0.6 47.2 35.3 44.8 64.5 21.8 462.5 58.0 25.0 20.0 0.2 69.1 1.9 1.6 0.1 0.8 3.1 1.6 17.0 5.1 1.3 19.3 14.5 15.2 9.0 1.6 3.7 1.0 209.2 9.7 7.0 37.6 38.6 31.7 60.8 40.0 40.3 35.6 37.3 42.4 35.9 62.8 49.4 34.9 57.7 128.0 8.8 33.9 23.1 37.5 36.0 22.2 10.6 31.2 37.6 29.8 42.9 48.1 31.3 93.8 181.8 24.5 64.2 9.8 61.3 1.3 79.4 23.5 38.3 36.5 22.7 19.2 50.6 140.2 63.8 73.4 177.7 8.8 17.6 276.3 46.4 1448.9 13.5 41.0 31.1 95.6 317.6 89.0 3.3 30.4 346.1 48.0 27.2 37.5 23.6 2.1 10.6 15.2 50.5 57.1 57.9 24.7 44.6 163.4 220.4 20.9 19.8 19.7 40.4 62.1 19.9 17.6 22.3 17.5 416.3 8.2 15.1 48.3 44.7 LGR4 GPR48 ENSG00000205213 "Leucine rich repeat containing G protein-coupled receptor 4" Q9BXB1 11 27365961-27472790 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, Immunity, Innate immunity, Spermatogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 204.4;Distal enterocytes: 123.3;Glandular and luminal cells: 137.7;Syncytiotrophoblasts: 128.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 83.5;RPTEC TERT1: 100.4;U-2197: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030267, HPA054350" Uncertain Approved "Centriolar satellite" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" "HPA030267: AB_10610004, HPA054350: " "unprognostic (5.27e-3)" "unprognostic (5.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.59e-1)" "unprognostic (4.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "unprognostic (2.00e-2)" "unprognostic (4.63e-2)" "unprognostic (5.84e-3)" "unprognostic (2.10e-1)" "prognostic favorable (2.00e-7)" "unprognostic (5.01e-1)" "unprognostic (3.59e-1)" "unprognostic (3.54e-2)" "unprognostic (1.76e-1)" 16.4 16.8 10.2 8.1 10.2 2.4 16.1 13.0 9.2 7.5 10.2 36.8 22.6 10.2 13.3 13.7 10.2 9.0 19.4 7.8 10.5 51.5 55.7 3.2 1.5 14.1 10.4 22.9 59.7 6.4 6.8 34.4 12.8 15.4 36.8 44.4 18.1 16.1 14.4 18.3 24.7 13.2 13.4 11.7 31.0 13.9 10.1 4.4 15.2 8.2 3.0 10.1 11.7 18.0 28.3 50.7 49.5 5.7 4.5 3.1 56.0 15.7 14.8 13.8 11.8 7.6 0.5 0.1 10.1 21.2 23.2 45.8 83.5 31.1 23.5 0.2 37.0 15.3 28.4 36.1 1.4 1.6 0.1 4.1 19.5 9.5 21.0 57.0 7.0 0.0 4.5 0.1 5.7 9.0 0.1 2.7 47.9 76.3 20.4 0.2 33.8 3.3 100.4 12.1 0.7 6.0 7.7 45.7 4.6 37.6 15.1 23.4 22.6 10.2 8.2 82.6 14.6 18.9 15.2 0.0 17.3 0.0 6.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 10.2 13.0 9.2 7.8 10.5 14.1 10.4 12.8 13.4 10.1 18.0 1.7 3.2 0.5 204.4 1.4 30.3 13.5 33.1 38.7 18.6 17.2 14.1 26.6 24.3 15.4 44.1 25.0 55.1 0.4 123.3 3.9 21.4 7.1 75.4 11.5 3.9 16.8 3.4 35.6 50.7 29.2 14.5 43.3 137.7 0.0 78.6 3.6 60.7 8.1 25.2 51.6 47.1 20.3 5.3 5.7 2.2 5.0 1.6 7.2 15.0 2.1 109.8 0.0 36.7 62.1 31.4 48.8 17.0 0.6 11.7 37.9 19.4 14.5 14.8 6.6 6.9 13.0 1.3 1.4 36.8 21.9 128.6 1.8 6.3 55.5 19.7 LHB "CGB4, hLHB, LSH-B" ENSG00000104826 "Luteinizing hormone subunit beta" P01229 19 49015980-49017091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 248 "pituitary gland: 4493.5" "Cell type enhanced" "Detected in some" "Early spermatids: 3.7;Late spermatids: 4.1;Pancreatic endocrine cells: 8.2;Syncytiotrophoblasts: 10.3" "Cancer enhanced" "Detected in many" "melanoma: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.7;HEK 293: 1.5;Hep G2: 1.4;K-562: 1.3;U-266/84: 2.0" "CAB022241, CAB022707, HPA038925" Enhanced Approved Cytosol "Secreted to blood" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "CAB022241: , CAB022707: , HPA038925: AB_2676272" "unprognostic (8.12e-2)" "unprognostic (3.59e-1)" "unprognostic (2.34e-3)" "unprognostic (1.41e-2)" "unprognostic (8.89e-2)" "unprognostic (6.25e-2)" "unprognostic (3.90e-3)" "unprognostic (5.69e-2)" "unprognostic (7.04e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (6.78e-4)" "unprognostic (2.47e-2)" "unprognostic (1.68e-3)" "unprognostic (1.38e-1)" "unprognostic (4.46e-1)" "unprognostic (9.52e-2)" "unprognostic (4.86e-2)" 1.0 5.1 0.2 0.0 0.1 0.0 0.6 0.4 0.3 0.5 0.0 0.5 1.3 0.5 0.0 1.3 0.6 0.0 0.9 0.1 0.2 1.4 1.9 0.9 0.2 0.2 0.1 0.6 18.0 0.6 4493.5 0.0 0.2 0.9 0.0 0.0 1.1 0.0 0.5 3.1 1.5 0.0 0.0 1.2 4.5 5.0 0.1 0.0 0.8 0.0 0.0 0.3 0.6 0.3 0.1 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.9 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.5 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 1.3 0.3 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.7 0.4 0.4 0.0 0.6 1.2 0.6 0.5 0.0 0.6 0.0 0.5 0.0 0.0 0.9 0.6 0.0 0.1 0.1 2.0 0.3 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.4 0.3 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.3 0.5 0.0 0.0 0.1 0.3 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.0 3.7 0.3 0.0 0.2 0.0 0.0 0.0 0.9 1.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 4.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.1 1.4 0.1 0.2 0.0 0.0 0.0 0.2 1.1 1.6 0.0 0.0 10.3 0.1 0.1 0.1 0.1 LHCGR "HHG, LCGR, LGR2, LHR, ULG5" ENSG00000138039 "Luteinizing hormone/choriogonadotropin receptor" P22888 2 48686774-48755730 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.2;ovary: 2.1;testis: 2.2" "Cell type enriched" "Detected in some" 22 "Theca cells: 143.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009814 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 52: Non-specific - Transcription" "CAB009814: AB_2135467" "unprognostic (8.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.14e-2)" "unprognostic (2.97e-2)" "unprognostic (2.24e-2)" "unprognostic (5.22e-2)" 1.3 0.8 0.3 0.0 0.4 0.0 0.7 0.9 0.5 0.0 0.7 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.2 0.6 0.2 0.0 0.1 0.0 3.2 0.7 2.1 0.0 0.0 0.5 0.0 2.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 2.2 0.8 0.2 0.6 0.1 0.0 0.3 0.0 1.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.9 0.5 0.2 0.6 3.2 0.7 2.0 1.6 0.8 1.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 5.3 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.3 1.0 1.2 0.1 0.0 6.5 0.0 0.0 0.0 2.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.0 143.2 0.0 0.0 LHX6 LHX6.1 ENSG00000106852 "LIM homeobox 6" Q9UPM6 9 122202577-122229626 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.9" "Cell type enhanced" "Detected in some" "Early spermatids: 77.2;Endothelial cells: 32.1;Inhibitory neurons: 46.0;Late spermatids: 225.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 13.2;K-562: 9.8;NB-4: 18.4;PC-3: 12.3;U-87 MG: 9.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 6.5;basal ganglia: 7.1;cerebral cortex: 7.7;hippocampal formation: 7.2;hypothalamus: 2.2" "HPA047854, HPA058319" Approved Uncertain "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Plasma membrane" "HPA047854: AB_2680183, HPA058319: " "unprognostic (2.96e-1)" "unprognostic (2.86e-1)" "unprognostic (8.06e-2)" "unprognostic (6.18e-2)" "unprognostic (7.72e-2)" "unprognostic (4.49e-2)" "unprognostic (5.83e-2)" "unprognostic (3.47e-1)" "unprognostic (5.94e-3)" "unprognostic (2.15e-1)" "unprognostic (2.98e-2)" "unprognostic (9.14e-2)" "unprognostic (5.64e-6)" "unprognostic (1.77e-3)" "unprognostic (1.96e-1)" "unprognostic (1.08e-1)" "unprognostic (3.51e-2)" 15.9 0.8 10.7 1.9 7.1 0.0 11.8 0.0 6.8 4.5 0.0 3.5 1.1 3.5 0.6 2.1 3.5 2.8 5.9 6.5 9.7 1.6 0.2 3.6 1.0 0.0 0.0 2.0 1.1 0.9 0.3 2.7 0.0 2.5 1.3 0.1 2.3 0.8 2.3 2.7 3.4 3.3 0.2 0.1 2.2 5.6 1.3 0.7 3.3 2.8 1.0 5.6 4.0 3.1 2.7 0.0 0.0 0.3 0.0 0.0 4.0 0.0 0.0 0.0 0.0 13.2 3.3 0.0 2.8 0.0 1.1 0.0 1.4 3.6 0.0 0.0 2.1 0.1 1.0 0.6 0.0 2.5 0.6 0.0 0.8 0.0 0.2 0.0 4.7 0.7 9.8 0.0 0.0 2.8 0.0 18.4 2.8 0.4 12.3 0.0 6.2 0.0 2.2 0.0 1.9 0.4 3.3 1.0 3.3 0.5 2.7 0.0 0.8 0.8 1.3 0.0 0.2 0.3 0.2 0.2 9.6 4.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 7.1 0.0 6.8 6.5 9.7 0.0 0.0 0.0 0.2 1.3 3.1 13.7 0.0 0.0 0.7 0.0 0.1 0.2 3.6 1.8 0.0 1.3 1.5 2.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.2 0.2 0.1 32.1 0.0 2.7 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 46.0 0.0 0.0 0.3 0.3 225.9 1.2 0.1 0.0 5.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.9 2.5 6.7 0.5 0.3 0.0 0.0 0.1 0.0 0.2 LIF "CDF, DIA, HILDA" ENSG00000128342 "LIF interleukin 6 family cytokine" P15018 22 30240453-30246759 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.7;urinary bladder: 91.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 95.5;Club cells: 56.3;Endometrial ciliated cells: 71.7;Fibroblasts: 51.9;Glandular and luminal cells: 192.9;granulocytes: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 88.3;hTEC/SVTERT24-B: 113.0;hTERT-RPE1: 104.4;U-138 MG: 123.9;U-251 MG: 94.5;U-87 MG: 97.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018844, CAB025985" Uncertain Supported Cytosol "Secreted in other tissues" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" Cytosol "CAB025985: , HPA018844: AB_1852814" "unprognostic (1.28e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (8.79e-2)" "unprognostic (4.61e-2)" "unprognostic (7.36e-3)" "unprognostic (4.18e-3)" "unprognostic (1.17e-2)" "unprognostic (1.41e-2)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (6.78e-8)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (8.99e-2)" "unprognostic (4.71e-3)" 37.9 4.3 0.6 22.4 0.7 1.6 4.7 0.6 1.7 6.8 6.6 7.5 6.7 11.7 0.6 3.1 9.8 47.7 18.4 0.9 0.8 14.2 5.0 29.9 4.3 1.2 1.3 2.3 13.4 0.4 10.4 2.7 0.9 12.0 8.0 3.0 4.9 2.1 0.8 10.7 9.3 8.3 1.1 1.5 7.8 0.6 2.6 1.3 5.4 1.0 1.7 91.0 2.4 1.1 29.0 47.9 1.3 10.6 0.0 3.9 17.1 4.1 17.2 5.1 12.1 7.7 47.3 0.0 10.1 0.2 88.3 7.3 1.1 13.1 6.9 6.8 2.1 3.7 19.7 10.9 4.5 0.1 36.7 4.3 2.5 113.0 3.3 104.4 0.0 0.2 0.8 0.1 22.6 21.5 0.6 0.1 1.8 27.0 29.5 0.9 15.9 0.0 40.7 11.0 0.2 0.6 4.9 0.4 8.8 5.0 1.0 0.5 0.3 123.9 45.3 47.3 94.5 0.0 0.2 0.1 97.4 0.1 58.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.7 0.6 1.7 0.9 0.8 1.2 1.3 0.9 1.1 2.6 1.1 0.6 22.4 44.2 0.3 0.0 3.4 14.0 95.5 0.0 0.1 40.0 10.9 0.2 10.0 56.3 5.5 0.0 0.2 2.9 3.9 0.0 39.6 0.3 71.7 16.2 3.6 0.0 0.0 0.0 3.4 0.7 51.9 0.5 192.9 67.0 0.2 0.0 0.0 1.1 0.0 0.0 3.5 10.2 0.6 3.2 0.0 0.0 3.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 40.3 3.8 0.0 0.4 15.7 5.3 1.0 15.6 0.2 0.0 17.7 30.2 0.1 0.2 1.5 2.8 0.3 5.5 0.1 7.1 20.3 LIFR CD118 ENSG00000113594 "LIF receptor subunit alpha" P42702 5 38474668-38608354 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 318.9;Astrocytes: 376.8;Endothelial cells: 279.5;Hepatic stellate cells: 809.2;Oligodendrocytes: 275.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 88.0;HHSteC: 38.7;SCLC-21H: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 260000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.00e-3)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-3)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (1.11e-1)" "prognostic favorable (1.92e-4)" "unprognostic (1.78e-1)" "unprognostic (9.80e-2)" "unprognostic (2.73e-3)" "unprognostic (1.06e-1)" "prognostic favorable (1.40e-7)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" "unprognostic (1.65e-1)" 50.0 18.1 38.8 6.2 55.1 0.1 41.7 43.6 24.8 33.5 3.0 10.2 5.8 33.0 16.5 12.1 30.9 12.4 19.9 23.4 43.9 23.9 30.9 23.8 21.0 42.7 55.2 18.6 22.3 13.4 5.0 35.9 50.2 28.9 8.8 17.4 34.1 16.8 23.4 9.7 11.0 33.4 39.6 29.9 21.9 10.0 54.1 21.3 38.5 42.8 10.2 11.7 14.5 47.5 1.3 4.3 88.0 6.8 25.4 27.0 0.6 6.7 3.8 4.7 2.9 0.9 4.6 0.0 1.2 10.1 12.4 0.7 5.5 2.1 9.0 0.0 7.0 0.0 8.7 3.7 38.7 0.0 0.5 23.5 1.6 12.0 1.5 6.1 8.6 0.9 2.3 12.3 7.3 1.3 0.0 0.2 2.1 0.0 14.8 0.1 18.4 0.0 6.0 2.0 56.6 7.2 28.3 1.6 0.0 11.7 1.9 0.0 1.5 9.0 15.7 21.0 4.3 0.0 0.0 0.0 15.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.8 55.1 43.6 24.8 23.4 43.9 42.7 55.2 50.2 39.6 54.1 47.5 318.9 12.8 39.7 376.8 2.6 23.2 6.3 1.2 10.8 6.4 16.8 22.1 33.1 8.6 7.3 14.7 8.4 12.1 0.6 0.0 5.9 2.0 15.0 11.0 12.4 279.5 0.0 13.5 33.7 9.3 28.0 62.9 14.3 16.9 1.3 29.6 809.2 11.8 3.5 1.7 54.2 0.0 6.1 50.3 17.7 29.7 113.7 2.3 17.8 45.0 0.0 6.2 0.0 111.6 275.5 7.0 0.0 19.9 0.0 18.5 0.0 12.3 8.3 37.3 39.5 65.9 30.8 9.6 7.3 2.0 18.2 28.6 3.7 15.8 0.0 5.5 LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 5 "Hofbauer cells: 22.0;Kupffer cells: 79.9;Macrophages: 39.1;monocytes: 48.7" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 31.6" "Group enriched" "Detected in many" 6 "granulocytes: 31.6;monocytes: 11.6" "Cell line enhanced" "Detected in some" "NB-4: 1.7;REH: 2.0;THP-1: 4.0;U-937: 9.1" "Secreted to blood" NA NA 140000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.04e-1)" "unprognostic (7.72e-2)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.53e-5)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (5.58e-2)" "unprognostic (3.30e-4)" "unprognostic (4.21e-2)" "unprognostic (6.59e-2)" 5.2 3.2 0.9 2.8 1.0 15.5 1.8 1.0 1.5 0.9 0.9 1.5 0.2 1.0 0.2 0.9 4.0 0.4 1.9 1.0 1.0 1.4 3.4 10.3 0.2 2.0 1.2 0.8 1.4 0.1 0.8 0.1 2.0 1.4 0.2 0.2 1.7 0.1 0.5 0.7 1.7 0.4 1.1 57.4 1.6 0.8 1.6 0.2 0.8 0.2 0.3 2.2 1.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.0 5.3 7.6 3.0 0.1 11.6 0.1 0.1 0.1 0.1 3.3 0.3 0.1 0.1 31.6 0.4 11.3 0.7 0.1 6.1 0.9 1.0 1.0 1.5 1.0 1.0 2.0 1.2 2.0 1.1 1.6 1.8 0.2 3.2 3.0 0.0 0.3 0.3 1.6 0.0 0.0 0.9 0.4 0.1 0.5 1.5 1.8 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.8 0.0 0.2 0.2 0.6 0.0 0.1 6.3 0.1 0.4 0.4 22.0 0.0 0.0 0.0 0.0 79.9 5.9 0.6 0.0 39.1 0.0 8.4 48.7 0.0 2.1 0.0 0.1 0.0 0.0 0.0 1.1 1.0 0.0 0.1 1.5 0.6 0.0 2.1 0.3 0.3 0.3 0.0 0.1 0.4 1.4 0.0 0.0 0.6 LILRB3 "CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB" ENSG00000204577 "Leukocyte immunoglobulin like receptor B3" O75022 19 54216278-54223506 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.0;lymphoid tissue: 49.9" "Group enriched" "Detected in many" 5 "Hofbauer cells: 63.4;Kupffer cells: 88.6;Macrophages: 88.8;monocytes: 71.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.8" "Group enriched" "Detected in many" 4 "granulocytes: 44.8;monocytes: 15.4" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (7.51e-2)" "unprognostic (3.52e-2)" "unprognostic (9.59e-2)" "unprognostic (4.53e-1)" "unprognostic (1.83e-3)" "unprognostic (5.28e-3)" "unprognostic (2.91e-2)" "unprognostic (2.55e-1)" "unprognostic (5.58e-2)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-8)" "unprognostic (2.18e-1)" "unprognostic (2.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.75e-1)" 9.9 3.4 0.4 8.3 0.4 14.6 2.9 0.4 2.1 1.2 0.9 2.7 0.3 1.2 0.3 1.3 5.4 0.1 3.4 0.4 0.4 2.3 4.1 27.0 0.3 1.2 0.8 1.0 1.9 0.0 1.3 1.2 1.3 1.7 0.0 0.2 2.4 0.0 1.1 0.8 2.6 0.1 0.6 49.9 2.3 0.5 1.8 0.6 1.6 0.0 0.2 3.2 1.6 1.4 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 15.4 0.6 0.1 14.3 0.2 0.1 0.3 0.0 7.2 0.1 0.0 0.1 44.8 0.0 5.6 0.5 0.0 11.6 0.4 0.4 0.4 2.1 0.4 0.4 1.2 0.8 1.3 0.6 1.8 1.4 1.5 9.6 13.0 0.3 2.2 2.4 1.2 6.5 0.0 0.7 1.6 2.2 0.4 4.3 8.3 1.8 0.0 1.5 2.1 0.6 0.0 0.3 1.3 0.8 1.9 3.0 0.0 0.8 0.2 0.6 6.7 2.9 0.0 2.2 7.6 0.5 1.8 3.2 63.4 0.0 0.1 1.9 0.0 88.6 8.4 4.1 0.3 88.8 1.8 1.9 71.2 0.9 3.1 0.0 0.1 0.2 1.3 0.7 2.1 1.6 0.4 0.4 5.2 2.9 6.6 4.3 1.3 0.8 1.5 0.1 3.0 1.2 3.8 2.6 2.0 0.4 LILRB4 "CD85k, HM18, ILT3, LIR-5, LIR5" ENSG00000186818 "Leukocyte immunoglobulin like receptor B4" Q8NHJ6 19 54643889-54670359 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.7;lymphoid tissue: 18.8" "Cell type enhanced" "Detected in some" "dendritic cells: 76.9;Hofbauer cells: 127.6;Kupffer cells: 118.9;Macrophages: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 37.3" "Group enriched" "Detected in many" 44 "dendritic cells: 37.3;monocytes: 10.8" "Cell line enriched" "Detected in some" 32 "Karpas-707: 407.8" HPA052807 Approved NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052807: AB_2681958" "unprognostic (4.09e-2)" "unprognostic (5.75e-3)" "unprognostic (6.06e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.03e-2)" "unprognostic (3.53e-1)" "unprognostic (4.13e-2)" "unprognostic (1.52e-1)" "unprognostic (5.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.91e-2)" "unprognostic (1.08e-1)" "unprognostic (4.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.52e-2)" 8.6 4.6 2.2 10.9 2.5 2.0 3.6 2.7 4.2 1.1 2.2 4.1 1.6 0.9 0.3 1.0 4.0 1.7 2.3 2.2 2.8 2.2 2.9 13.7 11.4 3.8 3.2 0.7 1.6 0.1 2.2 1.4 3.5 1.9 2.3 0.1 3.6 0.3 0.5 0.5 6.3 0.7 3.2 18.8 1.7 0.3 3.0 0.6 2.4 0.0 2.1 6.1 0.8 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 407.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.4 12.8 0.0 0.2 0.0 0.4 0.0 7.8 0.0 0.0 10.8 0.0 0.2 0.0 0.0 11.7 0.5 0.0 0.0 0.1 0.1 8.9 37.3 0.0 3.8 2.2 2.5 2.7 4.2 2.2 2.8 3.8 3.2 3.5 3.2 3.0 3.3 0.6 0.0 4.1 0.0 13.4 0.4 0.0 0.0 0.0 0.2 0.3 1.7 1.0 1.5 1.3 0.0 0.0 0.3 76.9 0.1 0.0 0.0 0.2 0.0 0.0 4.2 0.0 7.8 0.1 0.0 0.9 0.5 0.0 0.0 1.3 0.0 2.2 0.8 127.6 0.0 0.2 0.0 0.0 118.9 12.6 0.6 0.0 104.0 1.8 14.0 29.3 0.2 1.0 0.0 0.0 0.1 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.2 6.6 0.2 0.1 0.0 0.4 0.1 0.1 0.8 2.2 0.0 0.2 0.1 LIME1 "dJ583P15.4, FLJ20406, LIME" ENSG00000203896 "Lck interacting transmembrane adaptor 1" Q9H400 20 63736283-63739103 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 242.8" "Cell type enriched" "Detected in some" 5 "Plasma cells: 210.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 314.8;MAIT T-cell: 285.2;memory CD4 T-cell: 437.6;memory CD8 T-cell: 412.5;naive CD4 T-cell: 289.4;naive CD8 T-cell: 319.4;plasmacytoid DC: 749.3;T-reg: 689.4" "Group enriched" "Detected in all" 8 "dendritic cells: 749.3;T-cells: 689.4" "Cell line enhanced" "Detected in many" "Karpas-707: 33.9;MOLT-4: 37.9;RPMI-8226: 144.4;U-266/70: 71.1" "Low region specificity" "Detected in many" CAB015363 Approved "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 58: T-cells - T-cell receptor" "CAB015363: AB_629890" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (5.95e-3)" "unprognostic (3.01e-1)" "unprognostic (1.34e-1)" "unprognostic (3.85e-3)" "unprognostic (3.06e-2)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.94e-1)" "unprognostic (1.05e-3)" "unprognostic (1.51e-3)" "prognostic unfavorable (5.04e-5)" "unprognostic (2.39e-2)" "unprognostic (4.25e-2)" "unprognostic (1.67e-1)" "prognostic favorable (6.92e-6)" 8.9 5.6 2.2 5.6 5.6 4.7 5.8 2.6 7.0 8.8 0.8 11.8 2.2 5.9 0.0 11.2 6.8 0.0 5.1 2.9 1.4 54.5 242.8 9.0 10.7 2.8 1.8 9.6 5.1 0.1 11.3 0.1 2.5 13.4 0.3 0.0 12.5 0.4 3.9 13.2 18.7 0.0 1.0 43.2 18.3 5.9 3.5 6.1 11.2 0.0 1.2 7.6 9.2 4.8 2.0 0.6 0.1 0.4 0.0 0.0 4.9 2.6 0.2 0.3 0.0 1.1 2.1 5.7 3.8 0.1 0.0 5.1 0.0 0.3 0.3 2.5 4.8 1.1 2.3 25.4 0.0 1.5 2.1 0.2 0.7 0.0 0.0 0.0 0.0 16.4 2.1 33.9 0.0 1.1 37.9 10.7 2.0 1.3 6.6 25.9 0.8 144.4 0.4 0.3 2.0 2.9 1.3 1.3 2.8 0.0 1.1 0.8 0.5 1.8 2.8 1.9 1.5 71.1 3.0 12.7 1.5 1.1 0.7 1.9 1.5 1.8 314.8 1.0 285.2 76.4 437.6 412.5 2.4 37.2 289.4 319.4 10.6 85.5 1.7 749.3 689.4 193.8 2.2 5.6 2.6 7.0 2.9 1.4 2.8 1.8 2.5 1.0 3.5 4.8 0.0 0.0 0.0 21.5 7.2 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 7.7 0.0 0.0 0.3 22.4 0.0 0.0 0.0 0.4 3.1 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 5.6 0.1 0.0 0.0 9.0 9.6 0.0 0.0 0.0 210.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.8 0.1 0.0 36.7 0.0 0.1 0.0 LINC00514 ENSG00000262152 "Long intergenic non-protein coding RNA 514" 16 2988256-3002016 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 7 "brain: 3.2;lymphoid tissue: 2.5;skin 1: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "cerebellum: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.8;HaCaT: 3.8;hTCEpi: 2.6;MCF7: 2.0;OE19: 3.1;SCLC-21H: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (1.19e-1)" "unprognostic (8.43e-2)" "unprognostic (2.02e-2)" "unprognostic (2.23e-3)" "unprognostic (2.72e-1)" "unprognostic (2.78e-1)" "unprognostic (5.42e-2)" "unprognostic (3.44e-1)" "unprognostic (4.86e-2)" "unprognostic (3.87e-2)" "unprognostic (2.16e-2)" "unprognostic (6.27e-3)" "unprognostic (2.65e-2)" "unprognostic (2.50e-1)" "unprognostic (1.12e-1)" "unprognostic (4.10e-2)" "unprognostic (1.65e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.1 0.1 0.4 0.0 0.0 3.7 0.1 0.0 0.0 0.0 0.2 0.1 0.1 2.5 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.1 0.2 0.0 1.8 0.0 0.1 0.0 0.0 3.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 2.0 0.0 0.1 0.0 3.1 0.0 0.0 0.5 0.0 0.0 0.0 2.5 0.0 0.2 1.1 0.1 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.4 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 LINGO1 "FLJ14594, LERN1, LRRN6A" ENSG00000169783 "Leucine rich repeat and Ig domain containing 1" Q96FE5 15 77613027-77820900 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.1" "Group enriched" "Detected in many" 4 "Astrocytes: 271.0;Excitatory neurons: 271.6;Horizontal cells: 132.9;Inhibitory neurons: 220.5;Microglial cells: 167.7;Oligodendrocyte precursor cells: 240.8;Oligodendrocytes: 324.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 37.4;basal ganglia: 43.9;cerebral cortex: 56.1;hippocampal formation: 49.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 23.9;AN3-CA: 20.1;HAP1: 30.2;HEK 293: 21.0;MCF7: 13.5;NTERA-2: 56.9;SuSa: 21.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074653 Enhanced Supported "Plasma membrane" NA NA 25000 "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA074653: AB_2686706" "unprognostic (1.06e-1)" "unprognostic (7.07e-2)" "unprognostic (2.16e-2)" "unprognostic (1.48e-2)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.84e-2)" "unprognostic (3.77e-2)" "unprognostic (3.40e-1)" "unprognostic (1.10e-1)" "unprognostic (7.36e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (3.23e-7)" "unprognostic (2.07e-1)" "unprognostic (7.06e-2)" "unprognostic (2.85e-1)" "unprognostic (2.59e-2)" 3.9 1.1 37.4 1.2 43.9 0.0 3.5 0.0 56.1 4.6 0.0 2.2 1.5 4.5 2.2 0.9 2.7 2.1 11.8 49.1 0.0 4.2 0.8 1.0 0.7 0.0 0.0 2.3 2.5 4.1 1.9 6.7 0.0 1.6 0.8 16.2 3.2 2.0 0.8 2.8 1.7 4.6 0.0 3.3 1.4 5.3 0.2 0.3 2.2 1.4 0.3 2.3 2.9 4.6 0.0 2.1 23.9 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.4 0.0 0.4 0.1 30.2 0.0 0.0 0.0 21.0 0.0 0.0 0.4 0.3 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 3.3 0.2 0.0 13.5 0.0 0.0 56.9 1.3 0.0 0.0 0.0 0.5 0.0 0.0 4.2 1.2 0.1 2.4 4.9 21.6 0.3 0.4 2.1 0.0 5.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 43.9 0.0 56.1 49.1 0.0 0.0 0.0 0.0 0.0 0.2 4.6 2.1 0.0 0.0 271.0 0.0 0.3 0.1 0.0 0.0 21.8 0.7 0.3 7.3 1.5 0.0 0.0 2.1 0.1 0.0 1.8 0.0 0.3 8.6 0.8 3.7 2.3 0.0 0.0 271.6 0.2 0.2 1.8 0.0 0.2 0.0 14.9 4.2 0.0 0.3 132.9 220.5 0.3 0.0 0.0 0.0 16.5 0.3 0.1 3.6 167.7 0.0 51.1 0.0 240.8 324.2 0.2 7.7 0.4 0.0 0.0 0.0 0.0 0.0 19.5 26.3 0.0 21.9 0.2 3.1 0.0 0.1 0.3 0.1 0.5 0.2 0.0 LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 398.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 515.0;Kupffer cells: 714.8;Macrophages: 303.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.3;intermediate monocyte: 355.1;myeloid DC: 123.6;non-classical monocyte: 198.5" "Group enriched" "Detected in all" 6 "dendritic cells: 123.6;monocytes: 355.1" "Cell line enhanced" "Detected in many" "A-431: 354.4;AN3-CA: 367.8;ASC TERT1: 450.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" NA NA 280000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" 76.0 46.3 43.5 66.7 65.2 39.8 47.8 64.1 74.4 54.0 39.0 67.7 167.6 38.8 21.7 28.6 37.8 83.5 24.2 43.5 53.1 44.9 218.9 169.5 159.3 74.7 55.5 32.7 21.4 68.9 12.7 79.1 82.2 30.7 72.0 12.6 22.5 33.8 11.8 18.7 227.5 47.7 65.4 398.4 34.3 13.4 57.0 44.5 31.6 22.5 45.5 58.4 19.3 115.5 354.4 49.4 30.7 367.8 343.5 450.8 10.0 171.4 194.8 65.5 121.5 18.6 176.6 63.9 34.0 264.4 73.7 338.7 13.8 92.8 53.6 86.1 34.7 25.1 19.1 81.5 87.6 48.8 48.9 190.4 69.2 72.9 40.6 88.2 14.9 45.4 0.3 108.5 58.3 28.2 45.7 34.6 22.7 62.4 60.0 26.4 39.0 60.5 69.2 50.9 10.5 21.8 41.4 49.9 133.9 20.4 64.4 65.8 26.2 58.8 15.5 132.1 44.6 60.0 65.7 25.8 71.4 112.9 82.1 4.2 167.3 16.9 40.0 355.1 40.6 31.9 35.8 38.8 123.6 33.4 36.7 40.4 7.1 29.8 198.5 25.0 38.2 159.6 43.5 65.2 64.1 74.4 43.5 53.1 74.7 55.5 82.2 65.4 57.0 115.5 75.5 41.7 33.8 11.1 35.9 17.7 30.3 58.1 25.6 5.4 16.1 14.1 9.6 45.8 31.9 33.1 0.0 34.8 31.4 2.8 21.5 35.1 6.8 11.4 20.4 56.7 21.8 27.4 34.4 36.2 32.9 34.6 21.4 15.5 28.5 10.8 54.7 66.7 515.0 16.8 15.1 8.9 40.7 714.8 69.0 2.7 11.5 303.1 48.0 30.0 71.7 33.1 29.9 15.1 143.0 19.3 12.0 21.8 15.4 11.3 161.0 14.0 28.8 2.2 6.6 19.7 21.0 5.1 13.8 31.9 12.5 20.0 33.1 17.6 9.1 24.0 LIPC "HL, HTGL" ENSG00000166035 "Lipase C, hepatic type" P11150 15 58410569-58569844 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "liver: 171.0" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 161.7" "Group enriched" "Detected in some" 14 "liver cancer: 20.4;renal cancer: 10.4" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;NK-cells: 1.5;T-cells: 1.8" "Cell line enhanced" "Detected in some" "CACO-2: 8.5;EFO-21: 6.1;Hep G2: 24.4;HMC-1: 6.8;MOLT-4: 5.5;U-2197: 18.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 5500000 "Cluster 10: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.76e-2)" "unprognostic (9.15e-3)" "unprognostic (7.89e-2)" "unprognostic (7.15e-4)" "unprognostic (1.40e-1)" "unprognostic (1.33e-2)" "unprognostic (9.93e-3)" "unprognostic (6.25e-2)" "unprognostic (3.79e-2)" "unprognostic (1.10e-2)" "unprognostic (3.06e-1)" "unprognostic (2.31e-1)" "unprognostic (2.82e-2)" "unprognostic (1.41e-1)" "unprognostic (2.87e-2)" "unprognostic (1.80e-2)" "unprognostic (2.27e-2)" 0.4 0.1 0.5 0.3 0.5 0.2 1.5 0.8 0.9 0.4 0.0 0.6 1.8 0.2 0.9 0.6 1.0 0.8 0.5 0.6 0.3 6.0 171.0 0.3 0.7 0.8 0.7 0.8 2.5 0.0 1.5 0.4 1.0 0.1 0.8 0.1 0.2 0.9 0.0 0.6 0.8 0.1 0.6 0.8 0.5 0.1 0.4 2.1 1.2 0.3 0.2 1.6 0.3 1.2 0.0 0.0 0.0 0.0 0.3 1.0 0.1 0.1 0.8 0.0 0.0 8.5 0.0 0.0 6.1 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 3.0 0.0 24.4 0.5 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.2 0.1 5.5 0.8 0.0 0.1 0.0 1.1 0.3 0.0 2.6 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 18.4 0.0 0.1 0.0 0.1 0.2 0.5 0.0 1.6 0.1 0.0 1.3 0.1 1.8 0.0 0.3 0.9 0.1 0.0 0.4 1.3 0.2 1.5 0.2 0.0 0.9 1.1 0.5 0.5 0.8 0.9 0.6 0.3 0.8 0.7 1.0 0.6 0.4 1.2 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.8 11.5 0.7 3.7 0.0 0.0 0.9 1.2 5.9 7.8 0.0 0.4 0.5 1.2 0.0 2.7 6.1 3.7 0.1 2.9 0.5 2.7 0.0 0.2 4.2 161.7 0.1 0.0 4.3 0.0 0.0 3.8 0.8 0.1 0.3 0.3 1.8 16.9 0.6 0.0 3.1 0.0 12.9 0.2 0.0 0.0 0.0 0.2 0.3 15.7 0.0 0.0 0.0 1.6 0.3 0.0 0.0 0.3 0.6 0.0 1.1 1.2 0.0 0.1 LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401514-42427388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 834.5;breast: 524.7" "Cell type enhanced" "Detected in many" "Adipocytes: 76.1;Early spermatids: 127.8;Late spermatids: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "ASC diff: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006567, CAB017700" Enhanced Supported Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017700: AB_2135504, HPA006567: AB_2667618" "unprognostic (4.24e-2)" "unprognostic (2.46e-2)" "unprognostic (8.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-3)" "unprognostic (5.68e-2)" "unprognostic (2.84e-1)" "unprognostic (3.11e-1)" "unprognostic (9.44e-2)" "prognostic favorable (1.15e-4)" "unprognostic (1.52e-1)" "unprognostic (3.63e-10)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.76e-2)" "unprognostic (2.34e-3)" 834.5 45.1 22.7 7.7 71.7 5.0 524.7 77.2 41.5 5.1 0.6 10.9 5.3 6.4 1.2 8.6 5.8 3.7 32.5 23.8 42.6 7.7 1.5 3.7 7.3 100.3 73.9 4.9 6.2 4.7 6.9 2.9 90.0 7.1 1.4 2.0 17.2 2.6 19.7 23.6 24.4 2.6 44.0 14.4 8.5 68.6 57.1 6.9 9.6 23.3 3.7 14.2 7.7 116.9 12.7 9.6 6.0 2.3 136.8 1.3 0.1 5.8 3.1 9.2 8.5 2.3 4.6 20.6 6.3 1.8 4.5 5.6 3.7 11.5 1.0 4.0 6.1 5.8 5.3 0.2 2.7 0.1 13.9 1.2 10.7 1.5 2.1 1.3 2.6 8.5 2.7 12.8 1.2 0.1 14.8 0.5 0.8 9.7 2.7 12.2 1.1 6.9 2.6 13.1 8.5 8.8 5.1 5.7 5.6 0.3 1.5 7.5 4.7 2.5 7.8 1.1 5.3 9.7 8.5 15.6 6.3 0.7 8.7 11.0 8.6 3.8 2.5 4.7 2.3 3.4 3.2 3.7 3.6 4.5 2.8 2.5 1.5 3.6 2.7 2.9 3.0 3.1 22.7 71.7 77.2 41.5 23.8 42.6 100.3 73.9 90.0 44.0 57.1 116.9 76.1 0.0 3.3 4.2 8.1 4.1 12.1 2.4 4.6 11.0 4.8 2.9 2.5 0.0 2.0 1.8 10.4 0.1 4.8 1.3 1.9 8.0 127.8 0.9 3.4 10.2 0.0 5.3 4.6 2.7 0.1 2.0 3.6 1.5 0.0 6.6 17.9 0.0 0.6 8.4 6.7 2.0 6.1 2.2 2.4 236.5 3.1 0.8 5.4 4.7 0.9 4.0 6.2 6.0 37.9 1.8 0.7 1.5 3.0 6.7 18.4 1.5 0.8 13.9 0.0 7.2 2.1 39.4 13.1 2.5 2.4 0.0 5.1 5.2 2.9 10.7 LIPF "HGL, HLAL" ENSG00000182333 "Lipase F, gastric type" P07098 10 88664441-88678814 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 142 "stomach 1: 37213.5" "Cell type enriched" "Detected in some" 444 "Gastric mucus-secreting cells: 1509.7" "Cancer enriched" "Detected in some" 75 "stomach cancer: 278.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 4.1;MOLT-4: 3.4;NTERA-2: 3.4;REH: 2.1;RPMI-8226: 1.8;THP-1: 6.8;U-2 OS: 2.2;U-266/70: 3.1" "Region enriched" "Detected in single" 77 "olfactory bulb: 7.6" HPA045930 Enhanced "Secreted to digestive system" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA045930: AB_10959518" "unprognostic (1.53e-1)" "unprognostic (1.83e-1)" 6.3 2.8 0.0 0.0 0.0 0.0 4.6 0.1 0.0 3.9 0.0 13.0 262.0 1.9 0.0 117.9 5.4 0.0 3.2 0.0 0.0 11.4 4.9 7.3 0.0 0.3 0.1 2.2 4.5 0.0 7.3 0.5 0.1 6.7 0.0 0.0 2.6 0.0 1.6 2.0 1.9 0.0 0.0 2.6 37213.5 2.9 0.0 0.0 1.3 0.0 0.1 2.5 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 3.4 0.0 0.0 2.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 2.2 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1509.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LIPG EDL ENSG00000101670 "Lipase G, endothelial type" Q9Y5X9 18 49560699-49599185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "placenta: 149.3;thyroid gland: 242.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Extravillous trophoblasts: 67.9;Glandular and luminal cells: 49.0;Hepatocytes: 78.2" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 20.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 122.6;HaCaT: 189.8;RPTEC TERT1: 122.4;TIME: 247.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA016966 Uncertain "Secreted to blood" NA NA 657000000 810000 "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA016966: AB_1852893" "unprognostic (2.20e-2)" "unprognostic (3.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.25e-3)" "unprognostic (6.38e-2)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" "unprognostic (4.55e-3)" "unprognostic (9.93e-2)" "unprognostic (1.44e-1)" "unprognostic (6.44e-2)" "unprognostic (8.74e-2)" "unprognostic (2.98e-1)" "unprognostic (8.68e-2)" "unprognostic (5.64e-2)" "unprognostic (1.54e-1)" "unprognostic (1.35e-1)" 4.6 0.2 0.9 16.3 0.6 0.3 1.0 4.0 2.6 0.9 1.7 5.9 6.4 1.4 2.9 1.3 0.5 14.0 1.2 3.2 0.7 6.7 34.7 7.2 1.8 2.8 2.8 0.2 1.9 0.2 0.4 149.3 1.6 1.5 7.2 4.9 0.5 20.9 2.5 1.4 7.2 7.7 1.4 0.4 1.7 7.0 3.7 1.9 242.5 0.1 1.7 14.4 0.6 1.2 2.2 0.3 53.6 122.6 0.5 0.1 0.9 0.6 5.8 0.0 0.1 54.5 19.6 0.2 29.7 0.0 37.2 189.8 8.1 39.0 0.0 0.6 0.3 0.1 0.2 0.3 8.1 0.1 0.8 5.4 43.0 19.1 36.8 0.3 28.0 0.2 0.3 0.3 0.0 0.0 0.0 0.2 8.1 1.4 0.5 0.1 0.0 3.0 122.4 14.8 0.8 0.1 1.0 1.4 0.1 6.9 0.2 0.2 247.4 0.2 0.1 0.1 0.6 0.1 0.0 0.1 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.6 4.0 2.6 3.2 0.7 2.8 2.8 1.6 1.4 3.7 1.2 0.3 0.0 1.1 0.7 0.3 1.8 5.6 3.3 0.0 0.6 2.8 1.9 1.8 24.3 3.5 14.7 60.5 5.5 0.1 9.3 0.0 3.3 8.4 19.1 8.3 7.9 13.8 0.0 0.2 1.4 67.9 6.0 2.6 49.0 0.0 11.5 5.3 78.2 1.8 0.0 0.3 5.3 2.0 1.9 0.0 8.1 0.3 0.8 1.8 2.8 0.7 1.1 0.0 1.0 0.2 12.8 2.7 0.0 0.3 10.6 10.1 1.3 0.5 2.9 0.0 1.0 2.0 1.4 0.9 0.4 2.6 19.4 1.1 0.1 11.2 11.4 LIPH "LPDLR, mPA-PLA1, mPA-PLA1alpha, PLA1B" ENSG00000163898 "Lipase H" Q8WWY8 3 185506262-185552588 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.7;stomach 1: 48.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 144.2;Club cells: 135.5;Distal enterocytes: 312.3;Gastric mucus-secreting cells: 236.5;Intestinal goblet cells: 139.8;Proximal enterocytes: 226.1;Urothelial cells: 158.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 74.1;OE19: 17.2;RPTEC TERT1: 36.7;T-47d: 17.6;U-266/84: 18.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA049079 Approved "Secreted to blood" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA049079: AB_2680623" "unprognostic (4.50e-3)" "unprognostic (2.07e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (3.38e-1)" "unprognostic (1.01e-1)" "unprognostic (8.59e-2)" "unprognostic (1.44e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (7.88e-2)" "prognostic favorable (9.20e-5)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (4.21e-4)" "unprognostic (1.15e-1)" 0.3 0.3 0.3 2.8 0.6 0.1 3.8 0.1 0.6 2.8 6.9 36.3 11.1 0.2 7.1 14.7 1.1 12.3 0.4 0.4 1.6 7.8 0.4 18.3 0.1 0.1 0.1 0.5 5.5 0.0 0.3 0.1 0.1 6.8 37.7 0.2 13.2 2.0 0.5 7.4 11.8 0.6 0.0 0.4 48.2 2.7 0.2 0.3 0.2 0.1 3.0 12.2 4.3 0.1 10.3 13.5 0.1 0.1 0.0 0.2 2.9 0.3 0.0 0.3 0.3 1.3 74.1 0.0 7.5 0.2 2.9 3.6 5.6 0.1 0.4 0.1 1.6 1.8 1.8 1.4 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 5.4 0.1 0.0 1.3 0.5 0.1 0.7 17.2 1.1 0.0 0.0 1.0 36.7 9.2 0.0 0.0 1.1 12.2 0.3 0.6 17.6 0.3 0.0 0.1 1.1 0.1 0.2 1.2 18.9 0.1 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.3 0.3 0.6 0.1 0.6 0.4 1.6 0.1 0.1 0.1 0.0 0.2 0.1 0.1 144.2 38.5 2.0 0.8 0.8 16.3 76.5 0.6 0.7 55.6 12.7 0.4 94.4 135.5 68.0 0.0 0.2 1.0 312.3 1.9 57.8 0.2 7.0 0.5 1.8 22.2 0.0 1.7 24.9 0.1 1.1 236.5 5.7 7.0 36.0 1.1 0.3 0.0 0.0 0.9 139.8 38.7 0.3 0.3 0.1 0.0 2.4 16.0 0.0 0.8 0.3 2.1 2.5 0.4 60.4 102.7 0.0 0.3 72.8 226.1 1.6 105.6 0.9 0.0 0.1 5.5 1.1 0.3 6.9 2.0 0.3 0.8 12.0 102.1 158.0 LIPI "CT17, LPDL, mPA-PLA1beta, PLA1C, PRED5" ENSG00000188992 "Lipase I" Q6XZB0 21 14108813-14210955 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "epididymis: 421.0" "Group enriched" "Detected in some" 4 "Early spermatids: 1.7;Excitatory neurons: 1.5;Inhibitory neurons: 2.0;Microglial cells: 1.9;Oligodendrocyte precursor cells: 2.0" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049665 Supported "Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA049665: " "unprognostic (2.60e-2)" "unprognostic (3.49e-1)" "unprognostic (1.12e-3)" "unprognostic (1.14e-1)" "unprognostic (1.08e-2)" "unprognostic (1.19e-1)" "unprognostic (2.05e-2)" "unprognostic (1.68e-1)" "unprognostic (4.53e-2)" "unprognostic (2.90e-1)" "unprognostic (3.64e-13)" "unprognostic (2.82e-1)" "unprognostic (4.14e-2)" "unprognostic (2.90e-1)" "unprognostic (7.87e-3)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.2 0.0 0.5 421.0 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.2 0.7 0.4 0.0 0.1 0.6 0.1 0.4 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LIPK "bA186O14.2, LIPL2" ENSG00000204021 "Lipase family member K" Q5VXJ0 10 88724544-88752756 "Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 32.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SK-BR-3: 2.6" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 8: SK-BR-3 - Unknown function" "unprognostic (7.65e-2)" "unprognostic (8.64e-2)" "unprognostic (3.57e-2)" "unprognostic (3.19e-7)" "unprognostic (1.25e-1)" "unprognostic (1.60e-2)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 LIPM "bA304I5.1, LIPL3" ENSG00000173239 "Lipase family member M" Q5VYY2 10 88802730-88820546 "Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 28.0" "Cell type enriched" "Detected in single" 11 "Suprabasal keratinocytes: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071276 Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "Endoplasmic reticulum" "HPA071276: " "unprognostic (7.72e-2)" "unprognostic (8.49e-4)" "unprognostic (1.42e-2)" "unprognostic (2.23e-4)" "unprognostic (6.70e-3)" "unprognostic (3.01e-3)" "unprognostic (5.75e-2)" "unprognostic (6.63e-2)" "unprognostic (5.61e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.59e-2)" "unprognostic (5.93e-2)" "unprognostic (7.05e-3)" "unprognostic (4.17e-2)" "unprognostic (9.02e-2)" "unprognostic (9.70e-6)" 0.1 0.0 0.0 0.2 0.0 0.1 1.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 28.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 LIPN "bA186O14.3, LIPL4" ENSG00000204020 "Lipase family member N" Q5VXI9 10 88759982-88779626 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase Ichthyosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "skin 1: 26.7" "Group enriched" "Detected in some" 4 "Macrophages: 7.5;monocytes: 2.5" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 2.9;eosinophil: 10.3;intermediate monocyte: 7.5;neutrophil: 5.4;non-classical monocyte: 8.5" "Group enriched" "Detected in many" 8 "granulocytes: 10.3;monocytes: 8.5" "Cell line enhanced" "Detected in single" "HL-60: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (2.01e-1)" "unprognostic (3.48e-1)" "unprognostic (1.13e-1)" "unprognostic (2.99e-1)" "unprognostic (1.08e-1)" "unprognostic (3.27e-1)" "unprognostic (1.07e-1)" "unprognostic (2.03e-2)" "unprognostic (9.75e-2)" "unprognostic (2.54e-2)" "unprognostic (4.40e-2)" "unprognostic (5.77e-3)" "unprognostic (1.65e-1)" 1.3 0.3 0.0 2.8 0.0 2.8 1.7 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 26.7 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 2.9 10.3 0.0 7.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 5.4 0.0 8.5 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.0 7.5 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 LITAF "FLJ38636, PIG7, SIMPLE, TP53I7" ENSG00000189067 "Lipopolysaccharide induced TNF factor" Q99732 16 11547722-11636381 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 701.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 2578.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 2578.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006960 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Golgi apparatus, Vesicles" "HPA006960: AB_1079254" "unprognostic (2.26e-1)" "unprognostic (4.96e-2)" "unprognostic (2.32e-3)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (4.07e-2)" "unprognostic (8.75e-3)" "unprognostic (3.60e-1)" "unprognostic (6.15e-3)" "unprognostic (1.04e-1)" "unprognostic (4.61e-2)" "unprognostic (5.01e-1)" "unprognostic (1.85e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.57e-2)" "unprognostic (1.60e-1)" 139.3 43.7 53.5 165.8 81.9 207.0 95.5 79.6 70.0 121.2 70.5 121.1 46.3 100.5 77.8 62.7 108.2 114.1 63.9 52.2 63.0 182.3 107.7 192.1 112.3 94.0 79.4 67.6 64.6 56.5 39.0 71.3 92.7 105.9 116.1 63.9 116.4 83.4 36.3 71.6 57.9 93.5 77.3 119.6 70.7 10.6 77.6 68.6 116.8 37.6 123.7 214.1 83.1 109.4 79.2 157.8 89.4 43.8 13.9 11.0 90.7 100.2 309.0 93.6 139.1 62.6 206.3 39.9 126.8 86.1 108.7 95.5 40.1 186.4 88.4 304.2 45.8 2.8 117.1 310.3 212.9 12.5 12.9 35.0 320.8 79.6 210.7 84.4 0.3 2.7 25.3 149.5 1.5 75.8 1.8 183.3 146.4 104.0 0.6 12.1 19.6 228.2 79.0 110.4 22.2 68.0 172.9 219.4 183.9 136.3 122.5 66.7 0.8 38.7 65.3 23.0 24.2 59.2 140.6 100.5 45.1 95.8 225.5 508.8 149.5 284.0 459.6 130.2 277.2 174.0 284.0 412.7 178.0 173.9 318.9 381.4 2578.1 274.5 81.9 220.1 350.3 584.9 53.5 81.9 79.6 70.0 52.2 63.0 94.0 79.4 92.7 77.3 77.6 109.4 297.5 44.8 70.0 7.5 176.7 157.4 336.2 365.4 68.3 2.2 180.5 157.6 48.8 148.7 222.2 163.7 0.0 56.4 505.5 305.4 485.2 245.8 2.3 112.2 151.9 76.3 17.5 18.3 1.1 72.9 471.9 156.7 39.8 108.1 214.9 1.1 94.2 52.9 227.8 0.0 1.6 153.1 175.0 156.9 701.0 11.3 56.2 422.0 156.5 7.5 391.8 232.7 433.5 11.6 59.5 123.3 236.1 68.4 186.3 239.8 23.3 104.3 150.3 5.4 52.6 89.6 176.1 0.2 5.4 37.1 132.1 37.1 278.7 16.6 88.9 368.6 LITAFD ENSG00000283516 "LITAF domain containing" A0A1B0GVX0 16 8881634-8885351 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "testis: 7.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" 0.0 0.1 0.6 0.2 0.2 0.8 0.0 1.4 0.9 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.9 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.4 0.2 0.2 0.1 0.2 0.2 0.1 0.2 0.2 0.0 0.0 0.8 0.3 0.0 0.0 0.1 0.2 7.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.5 0.0 0.2 0.5 0.2 0.0 0.1 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.6 0.2 0.6 0.1 0.3 0.3 0.4 0.0 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.1 0.0 0.1 0.2 0.0 0.1 0.4 0.0 0.3 0.2 0.6 0.0 0.1 0.3 0.7 0.0 0.0 0.1 0.1 1.1 0.3 0.2 0.2 0.2 0.2 0.4 0.2 0.1 0.0 0.5 0.2 0.2 0.7 0.4 0.1 0.3 0.2 0.2 0.6 0.2 1.4 0.9 0.9 0.1 0.1 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LIX1L MGC46719 ENSG00000271601 "Limb and CNS expressed 1 like" Q8IVB5 1 145933423-145958017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063598 Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA063598: AB_2685055" "unprognostic (5.21e-2)" "unprognostic (4.09e-1)" "unprognostic (6.84e-3)" "unprognostic (2.85e-2)" "unprognostic (3.71e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (9.81e-2)" "unprognostic (3.46e-1)" "unprognostic (3.87e-2)" "unprognostic (1.84e-3)" "unprognostic (3.51e-2)" "prognostic unfavorable (3.19e-5)" "unprognostic (2.10e-3)" "unprognostic (4.95e-1)" "unprognostic (1.25e-2)" "prognostic unfavorable (5.27e-4)" 21.0 19.0 14.6 15.2 15.1 6.4 16.0 13.8 13.1 27.1 15.6 23.0 6.7 27.6 11.1 9.8 21.1 15.6 16.3 12.9 13.5 9.8 10.2 15.6 20.4 15.0 15.2 36.9 5.8 7.5 16.3 16.2 14.0 16.2 9.2 19.0 9.4 20.8 34.8 8.1 13.3 25.7 13.9 20.8 11.3 6.6 15.8 16.6 10.8 31.5 20.8 21.1 16.9 15.0 7.3 10.3 31.0 34.5 63.4 53.5 0.4 16.3 29.4 24.8 18.1 0.8 6.7 19.6 17.5 33.1 9.3 0.4 14.6 13.6 23.3 18.2 4.5 10.9 11.0 10.4 20.8 26.2 24.8 32.9 6.2 20.3 29.3 39.9 48.7 25.8 16.4 30.6 39.9 0.2 34.6 21.8 9.0 0.1 13.2 23.2 15.6 32.4 25.7 0.2 11.1 31.6 33.5 0.1 24.9 12.8 1.2 20.3 38.0 41.9 11.5 27.6 27.8 24.5 18.7 19.9 29.5 21.4 20.7 4.0 2.2 3.9 5.7 2.2 7.0 3.0 6.6 5.8 2.1 3.1 6.1 8.0 3.7 3.8 3.8 3.3 5.4 2.6 14.6 15.1 13.8 13.1 12.9 13.5 15.0 15.2 14.0 13.9 15.8 15.0 29.7 0.0 5.8 11.1 23.1 11.3 10.6 10.8 11.4 17.1 3.8 7.5 17.5 14.3 4.9 11.0 8.4 1.4 18.6 2.8 3.9 9.6 10.4 2.3 21.6 36.7 12.6 23.5 5.1 10.0 4.3 28.4 2.6 3.5 5.1 10.8 45.7 19.6 21.1 13.5 6.1 1.4 8.2 24.3 43.8 3.6 35.8 18.8 28.4 15.9 27.4 28.1 35.0 8.5 7.0 11.0 1.2 56.4 17.8 7.5 0.1 7.7 3.0 13.6 26.3 16.8 37.9 24.1 4.7 3.1 7.7 0.8 37.4 21.4 2.1 4.2 LLCFC1 "C7orf34, CTM-1" ENSG00000165131 "LLLL and CFNLAS motif containing 1" Q96L11 7 142939343-142940868 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "testis: 66.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "unprognostic (5.05e-2)" "unprognostic (9.94e-2)" "unprognostic (5.49e-3)" "unprognostic (2.76e-2)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (3.29e-1)" "unprognostic (2.23e-2)" "unprognostic (1.85e-3)" "unprognostic (3.54e-1)" "unprognostic (2.02e-1)" 0.1 0.0 0.3 0.0 3.6 1.6 0.1 2.2 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 2.8 0.2 0.0 0.2 0.2 6.5 3.3 0.0 0.0 0.0 0.0 0.0 4.4 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 3.0 1.1 0.0 66.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 3.6 2.2 2.0 0.4 2.8 6.5 3.3 4.4 3.0 3.3 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LMAN2 "C5orf8, GP36B, VIP36" ENSG00000169223 "Lectin, mannose binding 2" Q12907 5 177331567-177351668 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 530.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003927 Approved NA NA 88000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 55: Plasma cells - Humoral immune response" "HPA003927: AB_1079257" "unprognostic (5.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.87e-2)" "unprognostic (1.85e-3)" "unprognostic (6.25e-2)" "unprognostic (3.90e-3)" "unprognostic (2.88e-3)" "unprognostic (2.06e-2)" "unprognostic (2.08e-1)" "unprognostic (1.51e-3)" "unprognostic (4.56e-2)" "unprognostic (6.67e-2)" "prognostic unfavorable (8.53e-4)" "unprognostic (4.43e-2)" "unprognostic (6.13e-2)" "unprognostic (1.45e-2)" "unprognostic (2.32e-1)" 72.0 79.5 40.1 63.2 43.5 77.6 65.3 42.4 49.3 76.7 62.6 77.0 91.4 74.0 136.1 147.1 70.3 57.0 74.7 44.5 43.0 85.5 207.8 78.8 66.2 45.2 41.5 69.6 155.9 49.9 60.8 72.6 43.1 64.7 40.1 14.7 117.9 48.7 50.6 64.6 81.2 36.2 41.7 86.9 82.4 93.5 46.4 54.8 97.2 29.2 42.7 67.0 73.1 43.6 108.6 196.4 57.3 317.9 201.5 76.2 298.0 122.1 120.8 105.6 132.9 326.2 254.0 115.9 286.2 162.7 196.3 163.9 69.6 242.9 39.6 556.7 166.6 73.9 136.7 196.5 196.2 155.4 210.7 140.5 94.2 106.0 94.8 118.3 142.3 100.3 90.8 452.0 79.3 318.5 115.8 268.3 82.7 159.7 174.8 132.4 97.6 404.9 99.5 122.6 94.9 105.4 113.3 191.9 205.0 51.9 150.4 349.5 145.5 168.2 108.0 89.2 182.7 252.0 200.8 114.8 234.5 217.8 186.6 569.9 411.8 476.9 408.9 379.2 349.7 252.1 295.6 342.9 358.8 256.6 241.0 280.7 552.6 364.8 346.1 500.9 350.2 828.4 40.1 43.5 42.4 49.3 44.5 43.0 45.2 41.5 43.1 41.7 46.4 43.6 82.7 57.7 74.5 12.1 114.8 57.0 147.9 384.3 47.8 33.2 100.9 74.4 44.6 124.4 229.9 108.5 16.7 312.7 147.4 168.3 52.8 233.2 103.8 87.2 99.5 99.5 58.9 71.8 7.0 237.3 444.4 120.4 70.8 131.2 77.4 97.2 81.8 223.4 240.4 55.5 8.3 190.0 266.5 105.0 85.3 28.2 88.0 107.4 120.9 13.1 116.4 89.0 162.7 13.0 9.7 226.1 130.9 63.9 388.4 146.1 186.1 111.9 151.9 46.5 65.7 70.8 108.9 275.8 192.0 134.1 69.9 530.3 112.5 111.8 160.6 165.6 LMNTD1 "FLJ36004, IFLTD1, Pas1c1" ENSG00000152936 "Lamin tail domain containing 1" Q8N9Z9 12 25409307-25648579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 14.7;fallopian tube: 17.0;testis: 14.8" "Group enriched" "Detected in some" 4 "Astrocytes: 15.0;Early spermatids: 49.0;Endometrial ciliated cells: 17.6;Late spermatids: 40.6;Respiratory ciliated cells: 14.6" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 6.2;RT4: 7.7;SH-SY5Y: 7.6;U-2197: 26.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA038640 Approved Nucleoplasm,Centrosome NA NA "Cluster 6: Non-specific - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Centrosome" "HPA038640: AB_2676127" "unprognostic (8.92e-3)" "unprognostic (3.21e-1)" "unprognostic (2.41e-1)" "unprognostic (1.19e-2)" "unprognostic (9.57e-2)" "unprognostic (1.68e-1)" "unprognostic (6.18e-2)" "unprognostic (2.42e-1)" "unprognostic (7.80e-2)" "unprognostic (3.89e-2)" 0.4 0.1 4.0 0.7 5.8 0.3 0.9 6.1 3.9 0.5 3.7 3.6 1.4 0.7 0.6 0.3 17.0 0.8 0.2 5.2 6.0 0.7 0.2 1.3 0.3 12.5 14.7 0.2 0.5 0.0 0.7 0.2 8.3 0.2 3.4 1.2 0.0 0.2 0.2 0.4 0.6 1.1 8.8 0.6 0.6 14.8 5.8 0.2 0.9 0.0 0.2 0.3 0.0 9.8 0.4 0.3 0.0 0.2 0.2 1.6 2.7 3.3 6.2 1.4 0.2 0.0 0.4 0.2 0.1 0.0 3.9 0.1 0.3 0.1 0.3 1.1 0.1 1.1 0.9 2.3 0.3 0.1 0.1 0.5 0.2 1.8 0.5 0.1 0.1 0.0 2.3 0.4 0.0 0.5 0.0 0.4 1.8 0.1 0.6 0.5 0.2 0.2 0.2 7.7 0.2 7.6 0.1 0.4 4.3 0.9 0.3 1.8 0.3 0.2 1.0 26.8 0.3 0.8 1.6 1.8 0.3 1.8 2.9 0.5 0.1 0.1 0.2 0.0 0.1 0.4 0.2 0.2 0.1 0.5 0.2 0.3 0.5 0.1 0.0 0.5 0.1 0.1 4.0 5.8 6.1 3.9 5.2 6.0 12.5 14.7 8.3 8.8 5.8 9.8 0.1 0.0 0.0 15.0 0.1 0.0 2.4 0.0 0.0 0.0 0.2 0.3 0.6 0.0 1.3 0.0 0.0 0.3 0.0 0.0 1.9 0.0 49.0 17.6 0.1 0.1 0.0 0.0 1.5 0.0 0.3 0.3 0.0 0.2 0.0 0.7 0.0 0.4 0.1 0.0 1.0 0.0 0.0 0.3 0.0 40.6 0.0 0.3 0.0 5.6 0.0 0.0 0.0 1.5 0.7 0.0 0.0 0.0 0.0 1.0 0.0 0.1 14.6 0.0 0.0 0.7 0.1 1.1 0.4 0.0 0.0 0.3 0.1 0.0 0.0 0.9 LNX1 "LNX, MPDZ, PDZRN2" ENSG00000072201 "Ligand of numb-protein X 1" Q8TBB1 4 53459301-53701405 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 77.5;Early spermatids: 171.7;Excitatory neurons: 123.8;Glandular and luminal cells: 83.0" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 9 "amygdala: 2.7;basal ganglia: 6.0;cerebral cortex: 10.3;hippocampal formation: 7.5;white matter: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 17.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002235, HPA071091" Approved Supported "Cell Junctions,Cytosol" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "Cell Junctions" Cytosol "HPA002235: AB_1079261, HPA071091: AB_2686344" "unprognostic (4.95e-2)" "unprognostic (1.74e-2)" "unprognostic (2.00e-2)" "unprognostic (3.16e-2)" "unprognostic (2.79e-1)" "unprognostic (2.31e-1)" "unprognostic (1.31e-1)" "unprognostic (5.62e-2)" "unprognostic (8.14e-2)" "unprognostic (1.06e-1)" "unprognostic (5.18e-2)" "unprognostic (8.56e-2)" "prognostic favorable (3.08e-7)" "unprognostic (2.67e-1)" "unprognostic (5.49e-2)" "unprognostic (6.81e-2)" "unprognostic (3.05e-2)" 21.9 2.5 2.7 2.1 6.0 1.0 14.3 0.1 10.3 6.1 0.0 6.7 9.4 4.2 0.6 24.4 6.4 5.5 8.7 7.5 0.1 10.6 4.4 2.7 2.1 0.0 0.1 2.1 16.3 11.9 4.3 24.6 0.4 5.9 6.9 3.8 25.1 7.2 5.9 11.8 9.0 3.0 0.0 0.9 9.5 4.4 0.6 3.3 17.9 12.0 4.1 4.3 7.9 3.1 1.4 0.5 1.6 0.9 2.7 5.8 8.0 1.2 0.6 0.0 0.0 2.9 8.9 1.7 1.1 4.3 0.4 1.4 0.0 0.2 0.0 0.4 4.6 2.2 1.5 1.5 1.3 2.4 0.7 4.4 0.2 0.3 0.0 1.9 2.7 0.8 1.9 0.8 6.4 4.5 2.2 1.7 4.3 17.7 0.7 1.2 0.6 0.7 5.6 8.2 2.2 2.1 0.6 10.8 0.9 9.1 5.7 1.1 7.8 10.0 2.6 3.1 1.6 3.6 0.5 1.1 8.7 2.0 1.5 0.3 0.0 0.0 0.1 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.0 0.7 0.4 0.2 0.2 0.0 2.7 6.0 0.1 10.3 7.5 0.1 0.0 0.1 0.4 0.0 0.6 3.1 77.5 0.0 3.9 4.9 1.7 8.2 18.0 14.5 24.5 7.5 13.3 7.1 1.6 12.8 15.5 7.3 6.2 30.6 1.5 18.5 19.6 13.7 171.7 37.7 7.6 16.0 13.8 3.6 123.8 11.7 22.1 4.8 14.3 83.0 2.5 1.5 2.9 6.2 2.5 42.1 42.2 13.4 14.2 0.3 2.1 47.9 4.4 1.3 5.4 11.2 0.4 2.2 2.1 43.7 4.0 12.3 26.5 8.6 0.9 8.5 14.5 2.9 17.9 5.8 0.0 10.0 2.2 0.9 2.6 32.2 11.9 14.9 1.9 1.4 14.2 15.2 LOX ENSG00000113083 "Lysyl oxidase" P28300 5 122063195-122078413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 27.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 67.1;Club cells: 38.4;Early spermatids: 41.9;Endometrial stromal cells: 34.0;Extravillous trophoblasts: 44.2;Fibroblasts: 79.1;Peritubular cells: 39.1;Smooth muscle cells: 32.7" "Cancer enhanced" "Detected in all" "renal cancer: 39.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 777.3;fHDF/TERT166: 1790.7;HSkMC: 356.3;U-138 MG: 475.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043930 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 550000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA043930: AB_2678736" "unprognostic (5.10e-2)" "unprognostic (1.03e-2)" "unprognostic (6.99e-3)" "unprognostic (3.64e-2)" "unprognostic (9.86e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.42e-3)" "unprognostic (3.06e-3)" "unprognostic (8.92e-2)" "unprognostic (3.21e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (3.93e-8)" "unprognostic (1.11e-3)" "unprognostic (9.92e-2)" "unprognostic (4.31e-2)" "prognostic unfavorable (3.32e-4)" 27.9 2.4 0.4 6.8 0.4 0.2 17.6 0.5 0.9 10.8 0.8 4.2 3.8 6.2 1.7 5.6 8.9 18.8 23.9 0.3 0.4 4.5 2.1 13.6 3.3 1.3 1.4 5.4 3.3 0.9 1.2 8.1 0.8 4.1 4.5 1.1 3.2 2.6 1.9 12.4 3.7 10.0 1.2 2.6 4.4 1.4 0.5 0.9 6.9 2.1 1.4 14.1 4.8 1.0 0.8 0.2 2.0 0.9 168.7 185.2 0.1 777.3 205.3 73.2 246.4 0.5 0.3 0.1 16.5 1790.7 3.7 0.2 4.5 3.5 196.4 0.1 2.0 0.0 16.3 9.3 203.4 0.4 0.1 356.3 4.4 137.6 7.4 329.3 95.3 0.1 0.0 0.1 83.6 0.0 0.1 0.3 6.4 0.1 1.9 0.1 7.4 0.9 4.9 0.5 0.5 4.2 72.1 0.1 12.9 29.8 0.6 0.6 6.8 475.5 23.2 272.8 9.3 0.0 0.1 0.2 207.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.3 0.4 1.3 1.4 0.8 1.2 0.5 1.0 20.0 9.6 1.1 0.0 0.2 7.8 1.9 67.1 0.0 0.6 1.3 1.1 2.1 0.0 38.4 0.0 0.0 0.8 0.1 0.0 0.0 7.2 41.9 8.4 34.0 9.4 0.0 0.0 0.3 0.6 44.2 79.1 0.0 6.6 0.0 0.1 10.8 0.5 2.2 1.7 2.0 0.0 2.0 0.8 21.6 5.0 14.0 1.3 5.4 1.9 0.6 0.0 0.0 0.0 0.0 1.3 0.0 39.1 0.3 2.8 0.0 0.1 8.3 1.7 19.7 1.1 32.7 0.8 0.6 1.8 10.7 4.8 1.1 0.4 0.1 0.9 LOXL1 "LOL, LOXL" ENSG00000129038 "Lysyl oxidase like 1" Q08397 15 73925989-73952137 "Disease related genes, Plasma proteins, Predicted secreted proteins" Oxidoreductase Glaucoma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.3;Extravillous trophoblasts: 145.8;Fibroblasts: 76.0;Smooth muscle cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 3.4" "Lineage enriched" "Detected in single" 34 "T-cells: 3.4" "Cell line enhanced" "Detected in many" "BJ: 66.5;BJ hTERT+: 75.2;hTERT-RPE1: 73.7;U-87 MG: 61.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042111, HPA063583" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 280000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA042111: AB_10794412, HPA063583: AB_2685050" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (3.05e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.52e-5)" "unprognostic (7.95e-2)" "unprognostic (2.49e-1)" "unprognostic (2.44e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.63e-1)" "unprognostic (9.83e-2)" "unprognostic (1.14e-3)" "unprognostic (4.51e-2)" "unprognostic (5.81e-2)" "unprognostic (1.41e-2)" "unprognostic (9.76e-2)" 12.4 3.1 1.4 5.4 0.8 0.8 6.8 0.2 1.4 12.7 12.3 10.2 1.9 16.0 1.4 4.7 8.3 5.0 27.9 1.7 1.9 8.7 1.5 10.1 4.4 1.4 1.7 8.0 3.3 2.2 9.2 8.0 1.1 15.3 1.4 0.0 7.6 11.9 3.8 6.4 5.6 4.9 0.8 3.2 7.8 2.4 1.9 0.9 5.2 1.9 2.3 16.6 14.8 0.6 3.3 0.0 0.9 0.0 45.6 54.8 2.2 66.5 75.2 27.6 48.7 1.3 1.7 0.0 12.1 49.1 6.9 19.9 0.3 0.2 6.5 0.0 4.3 0.2 2.0 0.3 6.2 0.0 0.1 45.0 0.0 20.8 0.2 73.7 1.0 1.2 0.0 0.3 33.3 2.4 0.4 1.3 6.3 4.4 45.1 0.0 38.7 0.6 2.5 12.0 5.5 0.0 2.0 0.4 0.0 6.5 0.4 0.0 4.9 53.8 47.0 42.8 25.8 0.2 0.0 0.0 61.9 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.9 0.0 1.3 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 3.4 0.2 1.4 0.8 0.2 1.4 1.7 1.9 1.4 1.7 1.1 0.8 1.9 0.6 4.1 0.0 0.6 3.3 0.1 5.9 7.6 6.0 4.0 0.9 2.3 4.8 92.3 2.8 0.9 9.2 0.0 2.2 0.6 0.1 3.9 5.2 1.7 9.2 8.0 4.1 3.5 0.0 0.5 1.3 145.8 76.0 8.6 9.3 1.3 5.5 12.1 0.1 6.6 0.0 0.4 0.6 2.0 0.0 6.2 1.3 9.9 0.9 10.6 0.0 0.1 6.4 0.0 1.5 0.3 12.2 0.1 21.1 0.1 4.8 0.4 2.5 1.2 0.4 0.0 6.0 32.7 8.9 4.9 2.4 3.4 5.1 3.4 0.3 1.1 5.0 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 41.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 26.9;Endometrial stromal cells: 26.9;Endothelial cells: 33.1;Extravillous trophoblasts: 22.0;Fibroblasts: 22.9;Hepatic stellate cells: 19.6;Sertoli cells: 26.3;Smooth muscle cells: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 935.5;BJ hTERT+ SV40 Large T+ RasG12V: 517.3;fHDF/TERT166: 602.7;TIME: 510.7;U-87 MG: 905.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 30.4 3.3 1.9 15.9 2.7 1.2 18.8 4.7 3.0 10.6 0.8 25.3 9.3 12.0 0.9 3.8 4.9 8.0 10.7 1.8 3.2 6.1 3.9 8.3 11.7 7.7 8.1 12.9 6.5 2.5 2.6 36.2 7.0 7.5 5.4 3.0 4.1 13.0 4.5 5.4 10.3 41.3 4.5 5.0 9.0 2.3 4.5 1.8 5.2 2.6 9.5 12.0 7.3 3.7 58.2 147.7 42.7 35.8 112.4 183.8 19.4 935.5 295.9 415.6 517.3 1.1 4.4 10.7 7.5 602.7 193.2 47.6 2.1 79.0 215.3 1.8 8.5 0.9 19.4 1.0 226.8 0.5 3.8 164.6 3.9 155.0 20.8 274.0 350.7 2.4 0.5 2.0 138.1 32.3 0.6 1.4 29.1 0.4 24.5 1.9 36.7 0.4 120.1 0.3 0.9 13.7 122.9 6.1 8.6 131.3 0.8 1.2 510.7 384.6 103.3 163.8 127.3 4.1 0.8 29.9 905.4 1.4 413.5 0.1 0.2 0.8 0.4 0.1 0.2 0.4 0.1 0.3 0.1 0.1 0.2 0.6 0.3 0.1 0.2 0.2 0.1 0.2 1.9 2.7 4.7 3.0 1.8 3.2 7.7 8.1 7.0 4.5 4.5 3.7 12.9 0.0 3.0 6.8 0.6 2.5 0.3 26.9 0.6 1.5 0.6 9.7 2.6 1.5 4.1 0.0 0.0 2.7 0.4 0.0 0.0 1.9 0.6 1.7 26.9 33.1 0.0 0.0 8.1 1.5 22.0 22.9 1.5 2.1 0.0 2.0 19.6 0.2 1.3 1.7 3.2 0.1 0.0 0.3 5.7 0.4 0.9 0.9 3.6 6.5 0.0 1.2 0.0 7.1 11.9 2.3 0.1 0.4 0.9 0.6 0.2 0.2 1.6 3.2 26.3 2.7 48.1 1.3 1.6 0.5 3.1 1.0 1.0 3.1 0.4 0.2 LOXL3 ENSG00000115318 "Lysyl oxidase like 3" P58215 2 74532258-74555690 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Oxidoreductase "Deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 14.0;Hofbauer cells: 17.9;Kupffer cells: 12.5;Macrophages: 12.3;Microglial cells: 30.0;Muller glia cells: 10.6;Oligodendrocyte precursor cells: 11.6;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "melanoma: 15.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 11.7;non-classical monocyte: 9.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 143.4;HDLM-2: 110.7;U-138 MG: 245.9;WM-115: 549.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035281 Approved "Secreted to extracellular matrix" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA035281: AB_10601766" "unprognostic (7.54e-2)" "unprognostic (2.53e-2)" "unprognostic (5.34e-3)" "unprognostic (4.55e-3)" "unprognostic (6.85e-2)" "unprognostic (1.96e-1)" "unprognostic (1.68e-3)" "unprognostic (6.84e-2)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.22e-2)" "unprognostic (7.33e-3)" "unprognostic (7.09e-2)" "unprognostic (3.38e-2)" 6.8 5.3 4.5 7.8 4.7 14.3 3.0 4.5 5.3 5.1 3.8 7.3 4.0 7.4 1.7 3.2 4.9 6.5 8.2 4.5 5.6 2.0 1.5 4.6 4.1 7.0 5.0 2.9 1.1 1.7 2.7 15.9 6.3 3.3 3.7 4.9 1.6 4.0 1.3 2.0 3.9 8.1 5.6 8.9 2.7 2.6 7.0 1.4 2.2 1.5 2.3 5.2 4.0 7.3 1.6 0.3 21.8 3.7 17.1 20.6 4.5 71.0 143.4 33.8 31.8 25.6 1.3 0.1 0.9 73.1 1.6 1.1 2.8 1.8 19.8 110.7 1.0 17.6 1.8 0.2 5.7 0.6 16.7 22.6 0.2 90.6 3.8 12.0 0.7 0.8 0.8 2.8 6.4 4.1 0.2 6.5 12.0 0.8 0.7 2.0 3.1 0.3 0.3 1.2 11.2 12.8 0.6 1.1 14.7 3.2 2.3 1.3 0.3 245.9 8.2 1.4 0.9 1.4 0.5 0.1 92.5 6.8 549.6 0.1 6.0 0.3 0.0 11.7 0.0 0.1 0.1 0.0 3.5 0.1 0.0 0.0 2.5 0.0 9.3 0.4 0.0 2.6 4.5 4.7 4.5 5.3 4.5 5.6 7.0 5.0 6.3 5.6 7.0 7.3 0.9 0.0 0.5 14.0 0.3 0.9 0.2 0.6 0.6 0.9 0.4 0.8 0.3 1.5 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.8 0.0 0.2 4.8 1.2 0.0 0.4 0.4 0.0 1.5 7.1 0.0 0.5 1.3 0.7 0.4 0.1 17.9 1.7 4.2 0.1 0.0 12.5 2.5 0.7 5.0 12.3 0.0 30.0 4.8 10.6 1.0 11.6 0.6 0.3 0.0 4.5 0.1 0.3 0.0 0.1 0.0 0.9 19.7 1.6 5.3 0.6 0.8 0.1 0.1 0.8 0.4 0.2 0.0 0.2 LOXL4 "FLJ21889, LOXC" ENSG00000138131 "Lysyl oxidase like 4" Q96JB6 10 98247690-98268194 "Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Basal respiratory cells: 141.0" "Cancer enhanced" "Detected in all" "melanoma: 44.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BJ hTERT+: 249.7;CAPAN-2: 301.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033876, HPA037609" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB033876: AB_2135101, HPA037609: AB_2675579" "unprognostic (9.91e-3)" "unprognostic (3.97e-2)" "unprognostic (1.81e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (7.71e-2)" "unprognostic (1.75e-2)" "unprognostic (8.38e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.57e-4)" "unprognostic (2.51e-1)" "unprognostic (4.97e-2)" "unprognostic (5.25e-2)" "unprognostic (5.77e-3)" "unprognostic (1.28e-1)" "unprognostic (6.10e-2)" "unprognostic (7.40e-3)" 8.2 2.4 0.7 1.6 0.9 0.5 11.9 1.1 0.7 11.8 2.3 10.4 1.9 7.0 3.0 2.0 7.8 1.8 3.0 0.8 1.2 6.6 6.0 4.4 0.4 1.3 1.3 7.1 6.6 1.2 1.9 5.8 1.3 6.6 1.8 2.6 19.6 10.8 8.3 4.0 3.2 7.6 1.0 2.7 2.9 5.5 1.0 1.4 7.0 1.5 0.7 5.0 7.4 1.0 0.0 1.6 0.1 0.3 6.9 29.5 0.9 32.1 249.7 2.6 26.6 5.4 301.6 0.1 28.4 25.1 1.1 0.3 0.1 0.0 2.2 0.0 0.2 0.0 4.4 13.3 6.7 0.0 0.0 3.3 0.0 4.4 0.0 0.4 0.1 0.0 0.3 0.0 0.4 0.0 0.0 2.3 0.6 0.1 0.5 0.1 2.9 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 8.7 0.2 0.7 0.7 0.2 53.7 3.2 1.1 0.0 0.0 0.2 0.5 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.7 0.9 1.1 0.7 0.8 1.2 1.3 1.3 1.3 1.0 1.0 1.0 0.3 6.4 1.5 0.7 0.3 0.9 2.1 141.0 0.0 0.4 6.5 6.5 1.6 4.3 17.5 31.3 0.0 0.2 1.7 0.1 0.0 11.1 0.3 1.5 1.2 0.9 0.0 0.0 0.1 0.5 0.4 6.0 0.0 4.2 1.3 1.1 2.2 0.4 0.2 0.0 0.1 0.2 8.2 0.0 2.1 0.4 4.1 0.2 0.0 9.4 0.0 5.4 0.0 0.0 0.0 3.0 0.0 1.5 0.3 7.9 0.0 0.4 6.3 0.1 0.0 5.2 2.2 0.1 0.2 0.1 0.9 0.4 0.2 0.7 0.0 3.4 LPA "LP, Lp(a)" ENSG00000198670 Lipoprotein(a) P08519 6 160531482-160664275 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Hydrolase, Protease, Serine protease" Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 76.7" "Cell type enriched" "Detected in some" 28 "Hepatocytes: 80.7" "Cancer enriched" "Detected in single" 38 "liver cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "RT4: 1.0" "CAB016072, HPA060604" Supported "Secreted to blood" NA NA 78800000000 1800000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "CAB016072: AB_2135240, HPA060604: AB_2684330" "unprognostic (2.16e-1)" "unprognostic (5.10e-1)" "unprognostic (7.75e-3)" "unprognostic (6.70e-2)" "unprognostic (1.60e-1)" "unprognostic (4.17e-3)" "unprognostic (1.59e-1)" "unprognostic (6.38e-3)" "unprognostic (3.63e-2)" "unprognostic (3.18e-1)" "unprognostic (7.45e-3)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (3.72e-2)" 0.0 0.1 2.0 0.0 1.2 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.2 0.4 0.1 0.8 0.0 0.0 0.8 6.3 0.5 76.7 0.1 0.0 1.8 1.9 0.2 0.6 0.0 0.0 0.0 1.3 0.6 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 4.2 1.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.2 0.0 1.1 0.8 6.3 1.8 1.9 1.3 0.2 4.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.2 0.0 2.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 80.7 0.0 0.0 1.3 0.0 0.0 2.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 LPIN3 "LIPN3L, SMP2" ENSG00000132793 "Lipin 3" Q9BQK8 20 41340821-41360582 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 214.9;Proximal enterocytes: 76.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA051466, HPA052667, HPA070640" Approved Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA051466: , HPA052667: AB_2681908, HPA070640: AB_2686288" "unprognostic (2.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (9.74e-4)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "unprognostic (6.91e-3)" "unprognostic (4.26e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.74e-4)" "unprognostic (4.29e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (5.60e-3)" "unprognostic (2.02e-1)" "unprognostic (1.35e-1)" "unprognostic (3.37e-3)" 19.1 7.3 5.6 3.7 5.4 0.3 18.0 4.6 6.8 19.4 8.4 24.0 41.6 14.1 13.1 32.2 17.7 5.8 17.9 5.6 5.2 31.5 30.0 9.1 2.1 6.1 5.2 14.5 15.1 10.3 12.6 3.6 5.4 19.7 13.2 1.3 16.9 9.6 3.3 40.6 32.4 5.9 5.3 5.7 12.3 3.3 6.2 2.0 26.9 2.5 3.2 13.3 26.2 6.1 12.4 12.0 0.7 7.1 18.6 28.8 9.1 7.5 10.3 9.0 12.1 22.3 10.7 0.6 9.1 16.7 9.5 30.6 3.6 19.6 5.6 0.3 6.9 0.6 19.8 11.5 3.0 0.0 8.1 20.8 24.3 15.3 5.9 10.4 2.3 0.3 3.2 0.4 11.3 26.5 0.1 0.3 1.0 7.6 12.1 0.1 0.2 0.9 30.9 15.5 0.9 0.2 10.0 12.6 6.4 5.6 14.8 6.2 0.7 0.6 2.9 10.1 0.1 5.8 3.3 0.1 0.2 0.1 0.6 0.8 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 0.6 2.3 0.3 0.2 0.1 0.1 5.6 5.4 4.6 6.8 5.6 5.2 6.1 5.2 5.4 5.3 6.2 6.1 7.2 6.4 12.3 12.1 0.8 14.4 8.2 10.0 3.4 0.0 12.7 11.3 0.8 10.0 6.0 11.0 0.0 2.8 0.2 44.4 5.9 8.7 21.6 10.0 12.5 3.2 14.9 2.7 1.0 3.8 3.5 9.4 19.9 33.1 1.3 16.2 5.0 44.1 3.3 0.0 0.3 21.9 4.1 2.2 6.0 214.9 3.1 1.0 10.6 8.4 0.0 5.2 0.0 1.0 0.2 6.4 28.4 2.6 0.1 3.8 76.9 11.8 4.2 0.5 32.9 8.8 8.2 1.0 2.7 4.7 12.6 2.6 1.0 5.2 23.2 4.8 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 937.4;heart muscle: 407.8" "Cell type enhanced" "Detected in many" "Adipocytes: 453.0;Cardiomyocytes: 489.0;Granulosa cells: 495.2;Horizontal cells: 206.9;Sertoli cells: 236.7" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cell line enriched" "Detected in some" 5 "AF22: 391.6" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 5 "basal ganglia: 79.2;spinal cord: 59.3" HPA048749 Supported Vesicles "Secreted to blood" NA NA 4200000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" 937.4 15.9 6.8 9.1 53.2 0.9 255.4 20.3 12.2 2.7 8.9 12.0 1.5 3.7 0.5 2.8 2.7 8.6 407.8 10.7 9.5 19.1 0.7 62.1 8.5 7.4 7.7 10.6 6.3 181.5 4.1 14.7 7.9 3.8 5.8 11.1 24.4 64.7 86.4 8.3 13.3 4.1 5.5 1.6 8.4 1.0 11.5 4.3 10.6 127.3 2.8 6.1 4.7 8.8 0.0 0.0 391.6 0.1 8.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.8 0.0 0.0 0.1 0.3 0.0 71.5 0.0 0.2 8.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.7 9.6 0.0 0.0 0.0 0.0 68.4 0.0 0.0 8.4 0.2 0.0 0.0 0.1 13.5 0.0 1.8 0.0 0.0 8.1 0.0 3.5 0.0 0.1 0.1 0.1 0.1 32.6 0.0 0.9 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 6.8 53.2 20.3 12.2 10.7 9.5 7.4 7.7 7.9 5.5 11.5 8.8 453.0 12.8 104.9 1.0 0.4 1.5 0.1 0.0 0.6 2.8 114.7 5.7 489.0 0.0 0.6 0.0 2.1 0.4 0.9 0.1 15.6 0.0 0.8 0.2 2.5 56.1 0.0 0.0 1.9 0.0 0.7 13.6 0.0 0.3 6.3 495.2 2.9 0.0 108.5 206.9 0.4 1.0 0.0 14.8 4.2 1.3 1.2 38.2 14.2 1.9 2.0 2.3 0.0 9.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.4 2.9 2.7 236.7 91.4 68.1 0.4 0.2 0.2 0.6 0.4 2.3 4.3 2.8 0.1 LPO SPO ENSG00000167419 Lactoperoxidase P22079 17 58218548-58268518 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Antimicrobial, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 404 "salivary gland: 1026.8" "Group enriched" "Detected in some" 6 "Breast glandular cells: 25.2;Early spermatids: 8.3;Late spermatids: 14.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "midbrain: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "THP-1: 9.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA028688 Enhanced Supported "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 43: THP-1 - Innate immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA028688: AB_10601909" "unprognostic (2.74e-1)" "unprognostic (5.12e-2)" "unprognostic (4.14e-3)" "unprognostic (1.56e-3)" "unprognostic (2.41e-2)" "unprognostic (9.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (2.40e-2)" "unprognostic (6.27e-3)" "unprognostic (6.32e-2)" "unprognostic (2.56e-1)" "unprognostic (0.00e+0)" "unprognostic (3.41e-2)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (1.22e-1)" 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1026.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 2.5 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.7 25.2 0.5 0.7 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 8.3 0.3 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 1.3 0.0 0.4 0.0 0.2 1.7 0.3 0.0 0.0 0.0 0.0 14.1 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.5 1.4 0.1 0.0 0.3 0.0 0.2 0.1 2.6 0.4 0.0 0.3 0.0 0.2 0.0 0.5 0.5 LRAT LCA14 ENSG00000121207 "Lecithin retinol acyltransferase" O95237 4 154626945-154753120 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "Acyltransferase, Transferase" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6" "Cell type enriched" "Detected in many" 6 "Granulosa cells: 104.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 11 "NTERA-2: 15.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA070726 Uncertain "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "Endoplasmic reticulum" "HPA070726: " "unprognostic (3.64e-3)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (4.75e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.65e-1)" "unprognostic (9.25e-2)" "unprognostic (1.03e-4)" "unprognostic (4.49e-6)" "unprognostic (6.11e-2)" "unprognostic (1.05e-1)" "unprognostic (3.98e-1)" 0.2 0.2 0.6 0.2 0.7 0.5 0.4 0.7 2.6 0.2 1.6 0.5 1.2 0.1 0.3 0.0 0.2 0.5 0.1 0.7 1.2 0.1 2.1 0.3 0.1 1.0 1.1 0.3 0.8 0.2 0.2 0.1 1.3 0.4 0.1 1.0 0.1 0.5 0.8 0.4 1.6 0.1 0.7 0.1 0.3 0.8 0.7 0.0 1.5 0.0 0.1 0.1 0.1 0.9 0.5 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.3 0.2 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 15.3 0.0 0.0 0.0 0.0 0.1 1.4 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.6 1.9 0.1 0.1 0.6 0.1 0.1 0.1 0.1 1.5 0.2 0.1 0.1 0.8 0.2 0.2 0.2 0.1 2.2 0.6 0.7 0.7 2.6 0.7 1.2 1.0 1.1 1.3 0.7 0.7 0.9 0.2 0.0 4.4 4.6 0.1 1.1 4.4 4.0 0.6 0.5 8.6 9.1 0.3 11.5 1.7 0.0 0.0 0.1 0.3 0.8 3.9 1.2 15.2 0.9 0.5 0.3 0.0 0.0 2.2 0.8 0.1 1.5 2.0 2.2 0.0 104.4 1.4 2.2 0.1 0.0 0.6 0.9 2.0 0.8 2.8 3.2 0.0 0.3 5.4 0.0 0.0 3.9 0.0 1.0 2.2 1.2 0.0 0.0 0.0 2.4 12.3 1.0 0.9 0.8 0.0 1.4 8.1 10.5 4.7 1.4 1.1 0.3 0.6 0.0 1.2 0.6 LRCH3 MGC4126 ENSG00000186001 "Leucine rich repeats and calponin homology domain containing 3" Q96II8 3 197791226-197888436 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 102.1;Oligodendrocytes: 139.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 38.9" "Lineage enriched" "Detected in all" 4 "granulocytes: 38.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012380, HPA017299" Uncertain Enhanced Cytosol "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" Cytosol "HPA012380: AB_1853260, HPA017299: AB_2669576" "unprognostic (1.25e-1)" "unprognostic (4.92e-1)" "unprognostic (1.43e-1)" "unprognostic (2.69e-3)" "unprognostic (1.05e-1)" "unprognostic (8.26e-2)" "prognostic unfavorable (2.95e-4)" "unprognostic (3.29e-1)" "unprognostic (4.13e-1)" "unprognostic (9.85e-2)" "unprognostic (1.64e-1)" "unprognostic (2.06e-2)" "unprognostic (1.79e-3)" "unprognostic (3.29e-2)" "unprognostic (2.67e-1)" "unprognostic (5.59e-2)" "unprognostic (1.32e-1)" 13.1 10.2 7.7 12.0 11.9 8.0 11.4 18.7 9.1 16.2 7.3 16.3 7.0 15.5 7.7 10.7 13.7 10.2 14.6 7.7 12.5 8.2 10.3 11.9 17.0 9.8 8.1 18.8 9.5 12.2 12.3 10.1 8.5 13.9 10.2 19.2 12.0 12.1 19.3 10.8 12.8 14.8 6.0 13.9 11.2 13.1 10.1 15.5 9.7 11.5 18.7 14.8 13.8 15.7 30.5 10.0 28.8 17.5 28.9 35.2 11.0 21.5 25.6 25.3 31.5 26.0 15.5 16.1 33.5 24.9 40.7 19.1 25.7 21.2 34.5 13.3 14.4 29.8 16.2 19.2 18.9 21.4 19.3 25.0 10.9 24.7 31.9 23.0 30.7 14.7 18.1 27.5 23.4 25.1 15.9 7.8 19.3 15.8 22.3 16.0 17.6 10.6 11.3 19.4 14.2 14.4 28.5 18.5 20.1 26.4 39.0 17.1 30.1 19.4 12.0 24.4 22.2 24.5 26.9 15.2 19.8 28.0 20.3 38.9 4.7 10.1 7.4 6.9 6.0 9.3 5.8 6.3 4.1 6.6 5.3 7.5 2.3 7.1 6.9 3.5 6.1 5.4 7.7 11.9 18.7 9.1 7.7 12.5 9.8 8.1 8.5 6.0 10.1 15.7 19.2 32.1 27.0 64.6 29.7 10.6 18.1 11.4 8.0 56.0 11.6 8.5 15.4 14.3 17.0 9.2 56.3 8.5 25.8 10.4 1.9 10.1 12.8 12.2 22.9 20.8 6.0 11.1 69.8 9.9 6.6 23.8 10.7 16.4 11.4 23.0 34.6 14.2 9.0 38.7 86.1 11.0 8.2 17.6 17.9 9.6 25.1 14.6 17.8 66.5 30.8 19.8 27.8 102.1 139.2 14.1 9.5 28.6 15.1 15.9 7.1 5.2 15.1 43.1 19.7 31.7 22.8 18.0 17.2 9.4 10.5 6.0 19.9 17.0 11.0 14.7 LRCOL1 ENSG00000204583 "Leucine rich colipase like 1" A6NCL2 12 132603150-132610582 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "epididymis: 50.1" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 33.2" "Group enriched" "Detected in some" 4 "endometrial cancer: 0.8;liver cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (5.09e-3)" "unprognostic (7.83e-3)" "unprognostic (3.26e-1)" "unprognostic (6.94e-2)" "unprognostic (3.15e-2)" "unprognostic (2.38e-2)" "prognostic favorable (7.04e-4)" "unprognostic (4.54e-2)" "unprognostic (6.08e-2)" "unprognostic (5.29e-2)" "unprognostic (4.66e-3)" "unprognostic (1.52e-1)" "unprognostic (6.50e-6)" "unprognostic (1.46e-3)" "unprognostic (9.63e-2)" "unprognostic (3.31e-1)" "unprognostic (4.00e-3)" 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.1 0.0 0.2 50.1 0.1 0.4 0.0 0.0 0.0 0.1 0.2 2.3 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 1.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.3 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.6 1.9 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.3 0.0 0.1 3.3 33.2 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.0 1.5 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.1 0.1 0.0 0.2 0.4 0.0 0.0 LRFN4 "FIGLER6, MGC3103, SALM3." ENSG00000173621 "Leucine rich repeat and fibronectin type III domain containing 4" Q6PJG9 11 66856647-66860475 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077570 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA077570: " "unprognostic (2.25e-2)" "unprognostic (5.90e-3)" "unprognostic (7.51e-2)" "unprognostic (2.01e-2)" "unprognostic (4.35e-2)" "unprognostic (6.73e-2)" "unprognostic (1.80e-2)" "unprognostic (1.03e-3)" "unprognostic (6.56e-2)" "unprognostic (6.93e-2)" "unprognostic (5.69e-2)" "unprognostic (9.45e-2)" "unprognostic (1.93e-1)" "unprognostic (6.80e-3)" "unprognostic (1.81e-1)" "unprognostic (2.85e-1)" "unprognostic (3.53e-1)" 15.3 13.4 10.8 2.2 9.2 3.9 12.7 10.6 14.1 11.5 0.0 14.8 1.5 13.4 0.1 8.0 11.6 0.7 12.3 10.6 4.5 12.0 2.6 8.4 1.6 3.8 5.2 6.3 3.0 1.2 7.9 0.9 2.3 8.8 1.3 0.5 9.2 2.3 9.6 9.4 5.9 1.0 2.1 7.7 8.3 22.9 6.0 1.2 5.8 2.0 0.6 9.2 10.7 6.3 22.5 18.9 3.0 8.7 2.3 4.5 0.2 14.5 4.7 8.7 4.7 12.0 10.8 10.6 17.1 5.4 9.6 13.2 5.2 5.0 1.0 5.2 16.7 7.8 51.3 4.6 14.6 16.5 19.8 6.6 7.8 4.0 4.0 5.3 6.4 14.4 21.0 0.4 1.3 47.2 30.5 55.0 25.0 10.2 32.4 22.0 11.8 35.0 3.8 0.1 16.6 16.0 21.1 17.5 51.1 0.6 24.0 12.7 15.1 12.1 23.0 35.0 14.0 10.2 10.1 2.3 7.6 18.2 9.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.1 10.8 9.2 10.6 14.1 10.6 4.5 3.8 5.2 2.3 2.1 6.0 6.3 4.8 0.0 1.1 10.7 1.1 2.2 2.5 7.1 0.0 18.7 3.6 5.7 0.7 0.0 2.9 3.7 4.2 0.2 1.9 15.9 0.0 1.6 17.1 7.6 18.4 4.0 1.8 1.3 9.1 0.8 1.2 4.9 4.1 10.2 1.3 9.5 2.2 0.2 5.3 13.5 9.5 12.3 6.1 3.1 2.2 29.6 3.7 4.3 5.4 1.9 7.6 2.0 3.1 5.0 6.8 4.3 9.6 1.5 1.9 5.9 0.3 0.5 2.6 8.6 0.0 3.8 6.0 5.5 2.2 2.1 1.7 0.3 2.1 11.8 16.2 1.8 LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5;cervix: 10.1;parathyroid gland: 11.1" "Group enriched" "Detected in some" 19 "Excitatory neurons: 873.9;Inhibitory neurons: 581.5;Oligodendrocyte precursor cells: 296.1" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 16.4;HSkMC: 3.1;RPTEC TERT1: 5.2;SCLC-21H: 8.8;U-138 MG: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA001177: AB_1079274" "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (5.10e-1)" "unprognostic (6.24e-2)" "unprognostic (2.39e-1)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (6.38e-3)" "unprognostic (2.61e-2)" "unprognostic (5.78e-2)" "unprognostic (2.70e-2)" "unprognostic (9.27e-2)" "unprognostic (6.02e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (6.07e-3)" "unprognostic (2.92e-3)" 1.4 2.2 5.3 1.0 7.5 0.0 1.4 0.0 16.5 10.1 0.0 2.0 0.2 2.5 0.6 0.5 3.3 1.0 0.6 7.9 5.9 0.2 0.3 0.7 0.0 0.8 1.4 1.6 0.3 11.1 0.8 1.1 4.9 2.4 1.0 2.6 0.3 6.4 0.2 0.6 0.4 1.5 0.8 0.6 0.7 0.9 2.0 0.3 0.5 0.5 0.2 6.1 5.2 4.3 0.0 0.0 1.7 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 8.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 10.7 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.5 0.0 16.5 7.9 5.9 0.8 1.4 4.9 0.8 2.0 4.3 0.5 0.0 0.0 29.7 0.0 0.3 0.0 0.0 0.0 8.2 0.1 0.6 1.0 2.8 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.2 0.3 7.8 0.9 0.0 0.0 873.9 0.0 0.1 7.9 0.0 0.6 0.0 0.2 0.0 0.5 0.1 0.0 581.5 0.0 0.0 0.0 0.8 1.7 8.4 0.1 1.8 24.4 0.0 0.4 0.0 296.1 11.8 0.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.4 1.5 0.0 2.1 0.0 0.3 0.1 0.2 2.1 0.0 0.1 LRG1 LRG ENSG00000171236 "Leucine rich alpha-2-glycoprotein 1" P02750 19 4536402-4540036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "liver: 944.2" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 793.0" "Cancer enriched" "Detected in many" 9 "liver cancer: 160.9" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 19 "neutrophil: 285.2" "Lineage enriched" "Detected in many" 44 "granulocytes: 285.2" "Cell line enhanced" "Detected in many" "Hep G2: 15.4;SK-BR-3: 15.7;THP-1: 26.2;U-937: 48.7" "Low region specificity" "Detected in single" "HPA001888, HPA001889" Enhanced Approved Vesicles "Secreted to blood" NA NA 21000000000 42000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA001888: AB_1079276, HPA001889: AB_1079275" "unprognostic (5.54e-3)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "unprognostic (1.42e-1)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (1.46e-3)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.66e-6)" "unprognostic (4.06e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.49e-4)" "unprognostic (2.60e-2)" 7.2 4.5 0.6 17.8 0.5 31.4 4.3 1.2 2.6 8.7 1.1 7.3 6.7 1.9 5.9 22.7 10.0 15.5 1.2 0.6 0.6 9.8 944.2 7.8 0.8 0.7 0.7 1.5 44.1 0.1 1.6 1.9 1.9 4.4 4.7 0.1 20.9 6.2 1.0 4.8 3.3 2.2 0.5 16.2 13.6 0.3 0.9 1.2 1.3 1.4 6.5 13.3 3.8 0.9 10.8 0.1 0.0 0.0 0.0 0.1 8.0 0.0 0.0 0.0 0.0 1.0 8.0 3.6 13.3 0.0 0.5 1.4 0.0 1.7 0.1 13.4 0.4 0.3 0.2 15.4 0.0 0.4 13.9 4.1 0.0 0.0 0.0 0.0 0.1 0.0 9.6 0.2 0.0 0.6 0.0 11.3 0.2 8.2 0.0 0.1 0.3 11.3 1.0 2.0 0.0 0.0 0.1 15.7 0.1 1.3 4.8 26.2 0.3 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.0 48.7 0.0 2.4 6.4 15.0 0.1 2.0 0.1 0.4 0.3 0.1 1.6 0.4 0.1 0.1 285.2 0.2 1.3 0.2 1.1 2.2 0.6 0.5 1.2 2.6 0.6 0.6 0.7 0.7 1.9 0.5 0.9 0.9 13.4 12.8 54.3 0.0 3.3 8.0 33.1 56.8 18.2 0.1 14.2 2.5 0.5 60.1 50.2 14.7 0.0 0.8 0.5 44.7 1.9 112.7 0.0 38.0 1.8 24.7 4.9 13.2 0.0 64.1 12.4 3.0 31.6 17.3 12.0 0.2 38.2 793.0 6.7 1.7 0.0 26.3 32.6 19.9 5.0 0.0 0.0 14.7 1.8 0.0 7.3 0.1 0.0 0.0 0.0 40.6 11.9 0.0 1.7 4.5 10.8 4.9 76.1 0.1 0.0 2.3 3.3 0.0 0.2 9.0 5.8 1.4 1.9 3.4 27.6 30.2 LRP1 "A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A" ENSG00000123384 "LDL receptor related protein 1" Q07954 12 57128483-57213361 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Endocytosis "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 109.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 273.4;Hepatocytes: 188.4;Leydig cells: 233.3;Peritubular cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "classical monocyte: 4.3;intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 21 "dendritic cells: 1.6;monocytes: 4.3" "Cell line enhanced" "Detected in many" "ASC diff: 484.8;ASC TERT1: 488.4;fHDF/TERT166: 222.2;HSkMC: 318.5;hTERT-RPE1: 248.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004182, CAB018621, HPA022903" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 180000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB018621: AB_627893, HPA004182: AB_2667163, HPA022903: AB_10602426" "unprognostic (1.65e-1)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (5.00e-2)" "unprognostic (4.33e-2)" "unprognostic (3.98e-1)" "unprognostic (8.68e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-3)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.29e-5)" 109.2 14.1 21.3 29.0 36.3 8.2 40.0 30.2 19.7 32.3 8.0 24.1 23.2 36.9 6.2 19.3 30.3 31.5 35.5 16.7 21.9 5.7 35.0 34.0 4.9 46.0 31.5 71.0 10.7 7.8 10.2 39.8 27.9 13.8 11.2 9.9 20.3 20.2 13.0 20.4 18.4 28.9 27.1 13.6 15.1 7.3 48.9 5.6 17.6 23.5 2.7 25.5 29.3 27.6 7.7 14.5 30.4 24.2 484.8 488.4 91.2 85.3 109.0 27.5 26.7 26.9 12.4 0.4 10.4 222.2 6.0 33.6 5.3 8.7 9.7 0.7 1.3 0.4 17.9 56.4 66.5 0.5 14.6 318.5 3.1 61.8 7.2 248.7 1.7 1.1 0.4 1.3 87.2 1.7 0.2 0.4 34.8 11.0 8.8 3.2 171.0 1.6 1.9 2.2 1.4 16.4 19.0 0.6 13.2 42.0 2.9 1.2 1.2 96.0 35.0 53.9 5.2 1.1 0.1 0.2 167.4 0.1 18.7 0.0 4.3 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 1.6 21.3 36.3 30.2 19.7 16.7 21.9 46.0 31.5 27.9 27.1 48.9 27.6 24.6 12.8 8.4 113.6 3.2 24.0 11.9 28.7 19.9 29.2 4.9 19.3 14.8 15.7 14.7 1.8 0.0 87.5 1.1 81.7 0.0 7.4 1.9 9.7 111.4 13.0 4.2 0.8 39.3 1.8 53.0 273.4 49.5 4.2 6.3 36.9 11.0 188.4 73.8 8.4 41.6 14.1 6.1 145.3 28.6 8.4 233.3 102.9 28.4 89.9 48.8 154.7 1.0 173.4 6.6 14.7 27.2 184.3 4.4 5.5 86.0 2.1 15.1 7.3 39.5 129.7 77.0 1.6 2.4 35.4 16.1 125.9 4.2 11.4 25.0 12.3 LRP11 "bA350J20.3, MANSC3" ENSG00000120256 "LDL receptor related protein 11" Q86VZ4 6 149818757-149864359 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 61.3;Respiratory ciliated cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017267 Approved "Vesicles,Plasma membrane" NA NA 1500000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Vesicles "HPA017267: " "prognostic unfavorable (2.31e-8)" "unprognostic (3.85e-3)" "unprognostic (1.68e-1)" "unprognostic (1.30e-2)" "unprognostic (5.17e-2)" "unprognostic (4.25e-3)" "prognostic unfavorable (2.01e-5)" "unprognostic (5.05e-2)" "unprognostic (1.47e-1)" "unprognostic (2.49e-1)" "unprognostic (3.29e-1)" "unprognostic (2.63e-1)" "unprognostic (4.76e-2)" "unprognostic (2.47e-1)" "unprognostic (6.75e-2)" "unprognostic (1.34e-2)" "unprognostic (4.23e-2)" 14.5 18.0 25.2 5.3 25.8 1.4 11.8 18.7 31.5 17.2 13.8 13.1 11.7 11.4 16.4 28.6 22.3 11.3 10.8 26.7 23.3 20.3 10.0 13.6 2.9 23.6 24.9 16.5 19.8 42.8 17.6 12.5 25.0 25.5 12.3 13.5 20.1 13.0 5.2 20.6 9.1 12.0 19.7 4.1 16.3 8.0 26.0 2.4 22.9 4.8 5.9 18.0 20.8 25.0 26.5 22.9 17.2 15.0 37.8 67.2 3.5 27.7 52.1 18.5 22.4 7.3 52.9 0.2 36.7 43.3 79.4 69.4 19.2 47.1 13.3 43.7 19.4 13.3 74.3 30.4 22.6 13.2 0.8 42.8 93.1 23.0 46.5 52.5 28.9 11.8 26.8 11.0 22.3 45.4 0.5 1.3 10.4 52.0 19.6 14.5 25.5 6.4 33.9 53.8 22.4 15.6 86.7 46.3 17.0 8.5 38.8 26.4 21.1 22.6 4.8 48.4 21.3 0.1 8.7 6.3 40.9 12.9 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 25.2 25.8 18.7 31.5 26.7 23.3 23.6 24.9 25.0 19.7 26.0 25.0 7.3 6.4 2.8 17.6 0.5 11.3 14.3 17.9 5.7 12.2 10.2 6.0 8.8 12.8 18.3 20.2 2.1 2.1 0.5 7.7 5.9 6.5 27.0 61.3 6.4 7.4 29.4 5.5 42.5 22.7 1.8 20.5 15.3 16.5 0.0 12.4 9.3 9.5 3.6 8.4 44.3 5.0 16.2 1.9 6.2 31.7 16.4 1.7 14.2 11.2 0.1 6.0 0.0 17.6 40.1 19.7 4.2 14.7 0.6 22.2 4.0 7.0 107.7 5.5 0.0 10.0 11.7 14.7 10.4 14.9 14.3 5.6 1.8 15.7 13.2 23.6 LRP1B "LRP-DIT, LRPDIT" ENSG00000168702 "LDL receptor related protein 1B" Q9NZR2 2 140231423-142131016 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.5" "Cell type enhanced" "Detected in some" "Astrocytes: 2119.8;Excitatory neurons: 3755.5;Inhibitory neurons: 2917.8;Oligodendrocyte precursor cells: 5568.9;Oligodendrocytes: 1203.1" "Cancer enhanced" "Detected in some" "breast cancer: 0.8;glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.5;HEK 293: 1.7;U-138 MG: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069094, HPA074788" Approved Approved Vesicles NA NA 370000 "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA069094: AB_2686082, HPA074788: AB_2797273" "unprognostic (5.31e-4)" "unprognostic (3.68e-2)" "unprognostic (2.61e-1)" "unprognostic (7.36e-4)" "unprognostic (5.19e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-2)" "unprognostic (3.49e-1)" "unprognostic (3.75e-1)" "unprognostic (7.02e-3)" "unprognostic (1.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.94e-3)" "unprognostic (4.85e-3)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-1)" 3.1 1.4 18.6 0.0 22.5 0.0 1.6 7.2 18.7 0.3 0.0 0.3 0.0 0.0 2.2 0.0 0.3 0.1 0.3 21.5 8.7 0.4 0.2 0.1 0.0 6.8 9.4 0.6 0.1 0.1 1.9 0.0 8.2 0.9 0.0 2.6 0.6 1.0 4.4 0.4 0.1 0.0 3.3 0.0 0.4 0.3 11.5 0.2 5.6 3.5 0.0 0.1 0.9 19.8 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.2 1.7 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.6 22.5 7.2 18.7 21.5 8.7 6.8 9.4 8.2 3.3 11.5 19.8 1.4 0.0 0.0 2119.8 0.0 0.3 0.5 0.0 3.4 14.9 0.2 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.1 1.7 0.2 0.0 0.0 3755.5 0.0 0.0 9.1 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.0 2917.8 0.0 0.0 0.0 0.5 5.4 1.2 0.1 0.0 142.4 0.0 2.4 0.0 5568.9 1203.1 0.0 0.0 0.7 0.0 0.3 0.0 0.2 0.0 0.8 0.0 1.1 0.4 0.2 0.3 0.2 0.3 0.0 0.1 0.2 0.0 0.8 LRP2 "DBS, gp330" ENSG00000081479 "LDL receptor related protein 2" P98164 2 169127109-169362534 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Hearing, Neurogenesis, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 70.5;kidney: 34.8;parathyroid gland: 44.7;retina: 29.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Cytotrophoblasts: 63.2;Oligodendrocytes: 300.1;Proximal tubular cells: 283.9" "Cancer enhanced" "Detected in many" "renal cancer: 29.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "AF22: 39.4;CACO-2: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA005980, HPA064792" Enhanced Approved Vesicles,Mitochondria No NA 74000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Mitochondria" "HPA005980: AB_1079278, HPA064792: AB_2685353" "unprognostic (1.87e-1)" "unprognostic (1.04e-3)" "unprognostic (1.32e-3)" "unprognostic (3.65e-3)" "unprognostic (3.18e-2)" "unprognostic (1.60e-2)" "unprognostic (1.64e-3)" "unprognostic (2.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (4.09e-2)" "unprognostic (4.38e-1)" "prognostic favorable (3.43e-5)" "unprognostic (1.37e-1)" "unprognostic (4.21e-1)" "unprognostic (2.44e-2)" "unprognostic (1.62e-2)" 1.5 0.0 5.5 0.0 23.4 0.1 9.6 18.9 13.5 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.2 7.5 14.6 34.8 0.3 1.2 0.0 30.5 17.5 0.0 0.0 44.7 0.1 7.5 31.9 0.0 0.0 29.3 0.9 0.0 0.1 0.1 0.0 0.0 14.5 0.0 0.0 0.2 18.7 0.0 17.3 0.0 0.0 0.0 0.0 70.5 0.0 0.0 39.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 64.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 23.4 18.9 13.5 7.5 14.6 30.5 17.5 31.9 14.5 18.7 70.5 0.2 6.4 43.7 1.0 3.0 0.3 0.2 0.0 0.0 2.8 22.9 15.1 2.1 2.8 2.5 3.7 87.6 63.2 0.2 0.0 17.6 0.0 3.1 0.1 0.1 0.5 0.0 0.0 1.8 0.0 2.2 1.8 0.0 0.1 2.5 0.0 0.0 0.8 5.1 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 2.5 0.0 1.9 0.0 33.1 0.0 1.5 300.1 0.0 0.0 0.0 0.0 0.0 0.0 283.9 2.2 19.5 0.0 0.0 0.3 0.1 0.8 0.0 0.0 23.1 1.7 0.0 0.0 0.2 LRP4 "CLSS, LRP-4, MEGF7, SOST2" ENSG00000134569 "LDL receptor related protein 4" O75096 11 46856717-46918642 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 46.7;skin 1: 31.6" "Cell type enhanced" "Detected in many" "Astrocytes: 123.1;Cone photoreceptor cells: 41.7;Distal enterocytes: 31.1;Oligodendrocyte precursor cells: 137.2;Oligodendrocytes: 31.3" "Group enriched" "Detected in all" 4 "colorectal cancer: 12.2;endometrial cancer: 8.6;glioma: 13.2;testis cancer: 15.6;thyroid cancer: 28.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 21.3;SuSa: 16.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011934, HPA012300" Approved Uncertain Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli, Mitochondria" "HPA011934: AB_1853286, HPA012300: AB_1853288" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.86e-1)" "unprognostic (1.33e-2)" "unprognostic (4.39e-2)" "unprognostic (9.73e-3)" "unprognostic (5.29e-4)" "unprognostic (8.61e-2)" "unprognostic (2.29e-2)" "unprognostic (2.77e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (7.59e-2)" "unprognostic (7.95e-2)" "unprognostic (2.76e-2)" "unprognostic (9.90e-3)" "unprognostic (6.79e-2)" 0.7 1.4 23.3 0.9 30.5 0.0 1.5 19.1 21.3 2.3 0.0 4.8 3.4 1.6 0.9 1.8 1.4 2.0 6.9 24.2 16.0 0.7 0.2 2.9 0.1 46.7 23.0 4.6 2.2 5.6 2.6 2.6 19.8 2.1 3.4 7.9 1.7 2.3 4.4 31.6 4.9 1.5 21.3 3.9 7.8 1.1 30.9 1.5 2.4 7.7 0.3 0.9 1.4 25.6 0.1 9.6 21.3 6.5 13.4 3.7 4.9 1.0 1.9 2.8 3.2 2.8 0.0 0.0 1.4 11.4 3.1 3.9 12.0 7.5 2.2 0.0 10.3 1.0 3.8 6.8 2.8 0.1 1.9 4.5 4.2 4.4 1.1 2.5 2.5 2.6 0.9 0.0 1.6 0.8 0.2 0.3 11.9 0.0 0.9 1.6 7.3 0.0 0.3 2.8 0.1 14.2 1.2 0.0 3.4 16.2 0.3 0.5 0.2 5.7 3.5 6.5 2.1 0.0 0.0 0.4 4.3 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 30.5 19.1 21.3 24.2 16.0 46.7 23.0 19.8 21.3 30.9 25.6 0.2 0.0 1.9 123.1 0.0 8.2 2.7 2.4 10.8 0.5 0.3 1.9 6.2 0.0 1.9 1.8 41.7 2.6 0.0 31.1 1.9 0.0 0.5 1.0 4.7 1.0 0.0 0.0 19.7 0.4 0.4 5.0 3.1 4.4 5.1 1.6 1.8 0.4 0.2 0.0 18.6 2.8 0.0 0.0 0.4 0.0 1.8 0.2 1.8 15.0 0.6 9.3 0.0 137.2 31.3 0.3 3.0 1.2 0.0 1.0 8.0 0.3 1.1 2.7 0.0 12.4 0.9 0.2 0.8 2.3 10.9 1.4 0.2 8.4 3.3 0.8 LRP8 "APOER2, HSZ75190, LRP-8, MCI1" ENSG00000157193 "LDL receptor related protein 8" Q14114 1 53242364-53328469 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 24.0;thyroid gland: 41.5" "Cell type enhanced" "Detected in many" "Astrocytes: 30.7;Bipolar cells: 45.3;Excitatory neurons: 35.9;Granulosa cells: 67.0;Inhibitory neurons: 116.4;Microglial cells: 43.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073031 Enhanced "Secreted in other tissues" NA NA 2000000 "Cluster 11: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "HPA073031: AB_2732217" "unprognostic (3.83e-2)" "unprognostic (6.06e-2)" "unprognostic (6.36e-2)" "prognostic unfavorable (3.46e-6)" "unprognostic (3.46e-1)" "unprognostic (6.13e-2)" "unprognostic (1.03e-3)" "prognostic unfavorable (7.02e-4)" "unprognostic (6.65e-2)" "unprognostic (1.86e-1)" "unprognostic (1.66e-1)" "unprognostic (9.11e-2)" "unprognostic (8.88e-16)" "unprognostic (7.73e-3)" "unprognostic (5.47e-2)" "unprognostic (6.98e-2)" "unprognostic (3.00e-2)" 1.9 1.4 13.6 4.9 14.2 5.3 1.4 13.6 15.4 1.9 15.5 1.4 1.4 1.6 1.8 7.5 2.7 1.3 1.2 13.7 13.3 1.4 0.3 2.9 5.2 11.2 10.6 1.1 0.7 0.4 5.2 2.0 12.9 1.1 1.8 11.9 1.5 1.2 0.7 1.6 2.1 2.0 7.9 2.6 1.0 24.0 13.4 2.8 41.5 0.4 4.8 1.6 2.7 13.3 22.2 37.4 18.0 22.5 10.1 10.3 22.9 30.5 19.1 32.4 24.2 10.4 23.2 29.3 29.5 13.3 48.0 35.7 13.3 25.2 15.9 22.2 11.4 20.8 43.3 20.2 9.5 38.2 31.9 3.4 2.7 33.1 17.0 5.8 26.6 24.8 7.5 14.6 6.5 23.6 21.1 19.8 34.8 21.0 27.4 32.1 25.8 31.6 15.6 15.3 38.7 15.3 13.1 67.0 14.6 11.3 8.4 25.1 25.5 9.5 14.6 23.1 51.4 25.6 37.5 12.8 47.9 54.4 53.3 1.4 0.4 0.2 0.5 0.1 0.4 0.3 0.3 0.3 0.2 0.4 0.2 0.3 1.3 0.4 0.1 1.3 0.5 0.2 13.6 14.2 13.6 15.4 13.7 13.3 11.2 10.6 12.9 7.9 13.4 13.3 0.8 0.0 6.1 30.7 2.2 1.5 2.5 1.6 0.0 45.3 1.2 0.8 2.6 0.0 4.3 0.0 0.0 2.1 8.9 0.3 0.0 2.1 7.4 4.4 2.5 4.1 2.4 3.4 35.9 2.4 1.8 1.7 0.0 10.1 1.3 67.0 0.7 0.1 1.9 26.9 116.4 2.2 2.0 3.2 2.1 5.1 0.6 2.4 0.0 43.1 7.0 1.5 5.2 17.6 2.4 4.4 0.2 2.6 4.4 13.7 0.0 0.1 10.2 2.8 0.0 2.8 2.2 3.6 1.1 4.4 1.4 9.7 3.0 1.8 0.8 8.1 LRPAP1 "A2MRAP, HBP44, RAP" ENSG00000163956 "LDL receptor related protein associated protein 1" P30533 4 3503612-3532446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 584.3;Syncytiotrophoblasts: 693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008001, CAB025518" Enhanced Supported Supported "Endoplasmic reticulum" NA NA 810000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "CAB025518: , HPA008001: AB_1853292" "unprognostic (3.20e-3)" "unprognostic (7.01e-2)" "unprognostic (2.30e-1)" "unprognostic (2.22e-2)" "unprognostic (1.37e-2)" "unprognostic (9.61e-2)" "unprognostic (1.01e-2)" "unprognostic (3.89e-3)" "unprognostic (8.58e-2)" "unprognostic (6.12e-2)" "unprognostic (2.14e-3)" "unprognostic (2.19e-1)" "prognostic favorable (4.67e-11)" "unprognostic (6.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.58e-1)" "unprognostic (5.61e-2)" 6.6 9.0 6.6 2.6 10.3 6.0 6.4 8.6 7.6 8.9 10.7 7.6 3.3 8.6 3.2 5.8 7.5 1.9 19.3 5.8 8.1 12.7 9.6 8.5 2.1 8.0 6.9 9.5 14.4 7.7 14.4 6.3 7.9 8.2 1.7 2.8 10.1 4.1 8.9 6.3 6.7 1.9 5.2 8.6 9.2 9.2 7.5 1.6 8.9 2.4 1.4 7.3 6.3 6.3 3.7 7.4 5.7 8.2 5.5 2.9 12.5 5.9 4.8 4.3 3.1 14.9 7.0 2.1 6.0 4.2 7.0 6.2 3.4 5.8 2.4 1.6 7.9 2.9 7.8 10.4 4.2 4.7 12.5 4.0 4.3 3.9 1.9 4.7 5.2 3.9 5.1 7.0 3.6 5.9 3.1 18.4 4.9 5.1 7.8 4.3 4.2 7.1 4.8 8.6 5.6 4.6 7.4 3.0 8.1 3.4 6.7 8.6 5.6 5.1 4.7 4.1 8.2 4.2 2.9 2.8 5.9 13.3 7.2 21.9 23.2 60.1 9.3 19.7 8.1 9.9 8.6 8.8 13.3 10.0 9.4 8.6 20.5 11.7 19.1 10.2 11.5 27.3 6.6 10.3 8.6 7.6 5.8 8.1 8.0 6.9 7.9 5.2 7.5 6.3 95.0 109.0 90.9 21.2 78.0 67.8 174.6 267.7 52.9 70.6 75.3 84.2 165.9 108.7 158.7 195.0 45.9 584.3 75.8 147.7 50.9 159.3 40.4 85.5 229.6 88.2 82.6 35.7 22.5 107.9 184.0 152.5 79.0 71.2 81.1 102.3 62.4 92.6 243.1 38.7 20.6 121.6 164.8 100.5 80.2 60.0 126.2 154.2 147.7 16.9 107.1 140.0 91.6 28.1 16.7 95.4 153.4 151.6 205.2 124.5 204.6 273.7 144.8 86.2 78.9 82.8 108.1 272.5 161.4 40.7 61.4 693.5 86.0 99.9 109.9 140.5 LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 76.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 31.3;Granulosa cells: 68.6;Leydig cells: 101.9;Peritubular cells: 31.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cell line enriched" "Detected in many" 5 "LHCN-M2: 1237.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" 8.1 2.4 1.6 1.1 1.7 0.2 12.9 1.6 2.4 22.5 1.7 2.7 1.6 15.7 12.1 6.0 17.3 27.4 13.2 1.7 1.6 2.8 3.5 3.2 2.1 1.6 1.7 76.2 2.3 2.0 2.4 0.6 1.5 5.6 3.3 1.8 2.7 3.2 2.1 3.0 2.3 6.0 1.6 3.3 6.9 5.0 2.3 6.2 3.8 2.8 1.0 4.4 5.8 1.6 0.0 0.0 58.8 0.5 6.0 29.4 0.1 1.6 18.2 0.6 2.8 0.0 0.2 0.0 3.4 1.5 7.3 0.1 0.0 0.0 4.3 0.0 1.4 0.1 0.0 0.1 8.3 0.5 0.2 28.1 0.7 21.5 0.0 141.1 140.9 0.6 0.0 0.1 1237.5 0.0 0.1 0.4 3.1 0.1 0.1 0.1 244.0 0.2 0.2 0.1 1.3 1.3 0.1 0.0 0.1 0.1 0.0 1.7 11.8 0.2 1.5 15.2 2.3 1.1 0.4 0.0 0.3 0.0 0.3 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 1.6 2.4 1.7 1.6 1.6 1.7 1.5 1.6 2.3 1.6 3.6 0.0 1.1 4.6 0.2 0.9 0.2 0.9 0.0 3.7 0.7 0.8 1.1 0.0 0.5 1.8 2.1 0.3 0.3 0.0 0.0 1.7 3.5 2.7 15.3 4.4 0.0 0.0 6.9 0.4 0.2 31.3 1.1 4.6 1.3 68.6 6.1 0.5 0.4 0.0 8.7 0.1 2.0 0.0 2.7 2.9 101.9 0.5 5.4 10.3 0.6 0.6 0.0 2.5 5.3 0.2 0.3 31.6 0.0 0.3 0.1 0.3 0.1 2.2 65.7 16.1 17.8 0.6 0.5 0.4 0.6 0.0 0.9 6.6 0.2 0.2 LRRC32 "D11S833E, GARP" ENSG00000137507 "Leucine rich repeat containing 32" Q14392 11 76657524-76670747 "Predicted intracellular proteins, Predicted membrane proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 78.0;Endothelial cells: 88.3;Extravillous trophoblasts: 164.2;Hepatic stellate cells: 95.3;Sertoli cells: 39.5;Smooth muscle cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Group enriched" "Detected in some" 6 "ASC diff: 115.0;ASC TERT1: 70.3;HSkMC: 44.0;HUVEC TERT2: 51.4;U-2197: 108.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055775, HPA058434" Enhanced Nucleoplasm "Intracellular and membrane" NA NA 98000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055775: AB_2732600, HPA058434: AB_2732622" "unprognostic (3.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (4.19e-3)" "unprognostic (1.16e-1)" "unprognostic (8.84e-2)" "unprognostic (1.39e-2)" "unprognostic (2.24e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (3.93e-5)" "unprognostic (7.99e-3)" "unprognostic (1.15e-2)" "unprognostic (5.22e-3)" "prognostic unfavorable (2.64e-4)" 104.5 34.3 12.6 10.5 12.6 2.4 63.6 11.2 11.8 56.2 8.4 23.2 8.9 36.4 6.2 10.3 31.6 29.0 55.7 9.6 10.6 64.7 11.3 109.0 4.3 12.2 13.8 13.5 12.0 7.5 16.7 53.0 13.0 24.9 6.1 1.3 12.8 11.0 23.6 26.6 21.4 15.2 10.9 28.9 21.3 3.6 15.0 2.0 42.3 6.2 1.5 36.7 28.8 11.5 0.0 0.0 1.3 0.0 115.0 70.3 1.4 0.4 0.8 0.1 0.1 0.0 0.0 0.2 3.1 1.9 0.0 0.1 0.2 0.0 0.1 0.0 0.0 11.8 0.6 0.0 2.2 0.0 0.1 44.0 0.0 4.1 0.2 0.9 51.4 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 7.6 0.2 0.0 13.8 7.5 0.8 108.3 0.0 0.1 0.0 1.9 5.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 4.3 12.6 12.6 11.2 11.8 9.6 10.6 12.2 13.8 13.0 10.9 15.0 11.5 78.0 0.0 4.3 0.0 1.7 14.5 0.3 0.0 1.8 0.0 0.6 0.6 10.4 0.0 1.3 0.0 0.0 1.9 0.1 0.2 0.0 0.3 1.3 0.1 1.9 88.3 0.0 5.3 0.0 0.0 164.2 26.4 0.5 0.3 2.5 0.5 95.3 0.6 3.6 0.0 0.1 0.4 0.0 3.1 19.0 1.9 9.0 2.9 17.8 14.0 0.0 0.4 0.0 0.0 0.1 0.0 2.2 9.1 0.2 1.4 0.0 0.4 0.7 0.1 39.5 2.1 47.6 0.4 4.7 0.6 12.5 8.3 1.6 0.4 0.1 1.2 LRRC3B LRP15 ENSG00000179796 "Leucine rich repeat containing 3B" Q96PB8 3 26622806-26717537 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 28.0;choroid plexus: 8.7;skeletal muscle: 9.5" "Cell type enhanced" "Detected in some" "Astrocytes: 256.9;Early spermatids: 115.3;Inhibitory neurons: 50.0;Oligodendrocyte precursor cells: 38.2" "Group enriched" "Detected in some" 9 "endometrial cancer: 0.7;glioma: 2.6;ovarian cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.5;SuSa: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015568 Approved NA NA "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA015568: AB_1853282" "unprognostic (1.22e-2)" "unprognostic (2.94e-1)" "unprognostic (1.87e-1)" "unprognostic (7.42e-2)" "unprognostic (8.82e-4)" "unprognostic (2.84e-2)" "unprognostic (1.55e-1)" "unprognostic (2.77e-1)" "unprognostic (1.91e-4)" "unprognostic (3.31e-2)" "unprognostic (2.63e-1)" "unprognostic (1.60e-1)" "unprognostic (2.82e-1)" 0.3 0.1 18.7 0.0 21.2 0.0 0.4 28.0 24.4 0.3 8.7 0.5 0.0 0.7 0.0 0.4 0.4 0.0 0.3 23.1 16.2 0.1 0.1 0.0 0.0 17.9 18.4 1.5 0.0 0.0 1.5 0.0 17.6 0.1 0.5 1.1 0.4 0.1 9.5 0.1 0.2 0.4 20.7 0.1 0.5 7.2 18.9 0.7 0.1 0.2 0.0 4.8 0.2 16.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 21.2 28.0 24.4 23.1 16.2 17.9 18.4 17.6 20.7 18.9 16.1 0.8 0.0 0.0 256.9 0.0 0.1 0.0 0.0 0.0 1.6 1.2 4.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 115.3 0.2 3.2 0.3 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.0 50.0 0.0 0.0 0.0 0.0 11.6 0.6 0.1 0.0 9.4 0.0 0.8 0.0 38.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4.6 0.0 1.6 0.6 0.0 0.1 0.0 0.1 0.1 0.0 0.1 LRRC4 NAG14 ENSG00000128594 "Leucine rich repeat containing 4" Q9HBW1 7 128027071-128032107 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5" "Cell type enhanced" "Detected in many" "Club cells: 33.2;Cone photoreceptor cells: 27.1;Horizontal cells: 55.5;Respiratory ciliated cells: 53.0;Rod photoreceptor cells: 35.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 38.5" "Immune cell enriched" "Detected in some" 5 "neutrophil: 13.1" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.1" "Group enriched" "Detected in some" 6 "AF22: 15.9;NTERA-2: 35.4;REH: 33.5;SCLC-21H: 18.2;SH-SY5Y: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051100 Approved "Golgi apparatus" NA NA 2100000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "HPA051100: AB_2797241" "unprognostic (7.98e-2)" "unprognostic (6.15e-3)" "unprognostic (2.85e-2)" "prognostic favorable (8.19e-4)" "unprognostic (2.33e-1)" "unprognostic (1.34e-3)" "unprognostic (3.43e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "unprognostic (3.23e-2)" "unprognostic (1.72e-1)" "prognostic favorable (6.98e-4)" "unprognostic (4.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-1)" "unprognostic (5.84e-3)" 2.3 6.7 8.4 2.7 11.4 10.9 0.6 7.8 38.5 1.6 0.0 0.9 0.6 3.2 0.3 4.1 6.6 3.2 2.6 14.4 0.0 3.2 1.9 6.0 1.8 0.0 0.0 4.8 0.4 6.8 1.8 4.4 0.0 0.7 0.5 4.3 1.5 2.8 0.8 0.4 0.8 1.6 0.0 4.7 1.9 6.2 0.0 5.1 0.5 1.8 2.1 1.5 2.8 11.9 0.0 0.2 15.9 0.0 0.6 0.0 0.0 0.9 0.0 1.4 0.4 0.0 0.0 0.0 1.1 1.5 0.0 1.4 0.0 0.0 0.8 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 2.0 0.0 0.1 0.1 35.4 0.0 0.0 33.5 0.0 0.3 0.2 0.0 18.2 10.9 0.0 0.0 1.3 2.5 0.0 3.7 0.4 1.1 0.2 0.1 0.9 0.0 0.0 0.0 0.2 0.0 2.3 0.5 0.2 2.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.1 0.0 0.6 0.0 0.0 0.1 8.4 11.4 7.8 38.5 14.4 0.0 0.0 0.0 0.0 0.0 0.0 11.9 1.8 16.0 14.3 5.5 0.6 0.1 1.6 5.7 0.6 11.3 0.5 0.4 1.4 0.0 33.2 1.8 27.1 0.2 0.7 0.2 0.0 0.1 6.6 11.6 5.2 5.1 0.0 0.0 18.3 0.0 0.3 1.2 0.0 18.7 1.3 1.8 11.0 0.1 19.8 55.5 22.6 0.0 2.0 11.2 0.7 0.9 0.0 1.6 1.8 9.4 0.6 0.8 0.0 11.6 2.1 0.0 0.5 0.7 0.9 4.5 0.1 0.6 53.0 35.1 0.0 2.4 2.0 6.2 4.6 5.6 0.0 0.4 0.5 0.7 0.3 19.0 LRRC41 MUF1 ENSG00000132128 "Leucine rich repeat containing 41" Q15345 1 46261196-46303616 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 133.1;Syncytiotrophoblasts: 142.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051941 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Nuclear bodies" Nucleoplasm "HPA051941: AB_2681669" "unprognostic (1.57e-2)" "prognostic unfavorable (5.50e-4)" "unprognostic (7.80e-3)" "unprognostic (2.23e-2)" "unprognostic (2.11e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.66e-9)" "unprognostic (6.09e-2)" "unprognostic (2.96e-2)" "unprognostic (3.38e-2)" "unprognostic (5.34e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (6.34e-4)" "unprognostic (8.11e-2)" "unprognostic (1.80e-1)" "unprognostic (6.31e-2)" "unprognostic (1.73e-2)" 37.7 43.5 30.4 19.1 31.1 20.0 36.7 29.1 32.7 45.0 28.0 41.4 22.7 50.7 29.0 44.3 45.9 30.9 36.7 31.7 31.4 33.4 36.0 33.7 20.7 31.9 30.2 48.5 41.6 44.1 44.3 34.0 29.8 43.3 19.8 19.4 37.6 41.4 55.3 43.3 29.4 35.4 30.4 28.5 35.1 32.7 30.9 29.9 38.7 33.2 22.7 44.8 39.5 32.6 42.2 30.2 51.1 55.8 67.7 84.0 48.1 42.7 78.6 60.8 40.6 25.7 13.7 26.7 55.5 102.0 81.4 32.0 50.5 60.5 30.7 32.5 54.7 43.5 34.3 37.7 94.6 27.1 22.1 103.8 80.1 56.9 68.2 87.0 78.6 49.3 43.7 26.7 67.5 26.8 36.2 36.0 76.9 27.4 29.3 29.6 26.4 43.4 68.4 50.9 47.4 54.0 57.8 56.6 69.5 78.3 33.5 80.9 52.4 53.0 23.9 44.8 41.5 43.5 21.8 11.8 49.7 20.6 37.6 30.6 32.7 15.5 21.1 30.8 22.6 18.7 22.9 24.0 46.4 22.0 24.9 19.3 3.3 32.7 21.7 26.4 24.4 30.2 30.4 31.1 29.1 32.7 31.7 31.4 31.9 30.2 29.8 30.4 30.9 32.6 19.0 19.2 22.7 17.0 17.9 28.4 36.6 40.4 17.1 23.7 28.6 24.8 11.3 28.6 32.0 35.0 25.0 83.1 20.2 27.4 39.2 42.0 28.2 57.5 36.2 22.0 36.6 24.0 19.8 30.0 48.7 34.8 23.9 133.1 7.0 42.4 25.7 28.0 36.5 47.1 21.1 30.4 30.5 20.6 22.8 19.3 34.8 20.7 10.6 11.2 23.5 25.4 20.6 18.6 22.3 30.1 24.2 33.1 26.5 36.7 38.0 32.7 23.4 27.4 39.5 40.4 32.1 46.6 45.8 21.2 29.0 142.6 18.8 37.7 30.0 34.7 LRRC4B "DKFZp761A179, HSM, LRIG4" ENSG00000131409 "Leucine rich repeat containing 4B" Q9NT99 19 50516892-50568435 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.2;cervix: 41.3;pituitary gland: 31.9" "Cell type enhanced" "Detected in some" "Astrocytes: 34.9;Bipolar cells: 19.6;Excitatory neurons: 32.1;Inhibitory neurons: 38.5;Oligodendrocyte precursor cells: 29.7;Oligodendrocytes: 48.9" "Group enriched" "Detected in many" 9 "glioma: 36.5;testis cancer: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.7;HMC-1: 32.1;REH: 8.7;SH-SY5Y: 27.5;U-2 OS: 25.3;WM-115: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058986 Uncertain NA NA 2700000 "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA058986: AB_2683871" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (4.46e-2)" "unprognostic (4.48e-2)" "unprognostic (3.56e-1)" "unprognostic (5.39e-4)" "unprognostic (2.70e-2)" "unprognostic (1.11e-1)" "unprognostic (5.28e-2)" "unprognostic (4.61e-3)" "unprognostic (1.11e-3)" "unprognostic (3.41e-1)" "unprognostic (3.15e-5)" "unprognostic (4.29e-2)" "unprognostic (2.61e-1)" "unprognostic (3.64e-1)" "unprognostic (2.17e-1)" 2.8 5.3 54.4 0.9 35.6 0.0 2.1 20.7 61.2 41.3 0.0 2.8 0.8 16.2 0.1 1.9 10.0 1.2 1.8 49.3 33.2 1.8 1.3 5.8 1.3 50.9 47.6 5.1 0.8 0.2 31.9 4.2 33.3 3.3 0.1 1.6 0.8 1.0 0.7 1.2 3.3 1.3 19.9 0.8 2.9 2.4 38.2 0.0 2.6 0.1 0.5 5.8 13.0 38.1 0.0 0.5 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 4.9 0.0 0.7 0.1 0.1 0.0 0.0 0.3 8.7 0.0 0.0 0.0 0.0 0.1 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.5 0.0 1.0 0.1 0.0 8.2 0.0 0.0 8.7 0.0 0.1 0.0 0.0 0.0 27.5 0.0 0.0 5.7 0.2 0.0 0.3 0.0 0.0 25.3 0.0 0.0 0.6 0.1 0.1 0.1 0.3 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.4 35.6 20.7 61.2 49.3 33.2 50.9 47.6 33.3 19.9 38.2 38.1 0.7 0.0 0.0 34.9 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 2.5 0.9 0.0 0.0 32.1 0.0 0.0 1.3 0.0 0.1 0.0 0.2 0.7 0.0 0.1 10.1 38.5 0.0 0.0 0.0 0.3 2.2 2.8 0.0 0.0 2.8 0.0 1.6 0.0 29.7 48.9 0.0 0.0 4.5 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 5.8 4.8 8.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 LRRC4C "KIAA1580, NGL-1" ENSG00000148948 "Leucine rich repeat containing 4C" Q9HCJ2 11 40114203-41459773 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.4;retina: 17.1" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 5497.5" "Cancer enhanced" "Detected in some" "glioma: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 19.1;U-2 OS: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054800, HPA075816" Supported Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA054800: AB_2682603, HPA075816: " "unprognostic (4.86e-3)" "unprognostic (3.43e-2)" "unprognostic (7.62e-3)" "unprognostic (4.87e-3)" "unprognostic (6.48e-2)" "unprognostic (1.42e-1)" "unprognostic (2.84e-1)" "unprognostic (4.64e-2)" "unprognostic (1.93e-1)" "unprognostic (2.22e-1)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (4.90e-13)" "unprognostic (5.05e-4)" "unprognostic (5.21e-1)" "unprognostic (1.12e-1)" "unprognostic (6.45e-3)" 0.7 3.4 11.4 0.8 14.1 0.0 1.4 0.5 15.4 3.0 0.0 2.5 0.4 1.2 0.3 0.4 0.5 0.8 2.1 14.4 9.6 0.3 1.1 0.8 0.7 7.8 10.7 0.6 0.3 1.7 4.0 0.0 5.7 0.6 0.7 17.1 0.6 1.6 0.3 0.2 0.8 1.3 4.6 0.6 0.5 0.2 8.1 0.6 2.3 0.7 0.7 0.7 2.0 9.2 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 20.9 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 14.1 0.5 15.4 14.4 9.6 7.8 10.7 5.7 4.6 8.1 9.2 0.2 0.0 1.3 498.2 0.2 0.1 0.0 1.4 0.0 35.5 4.2 3.0 1.2 0.0 1.4 0.0 6.2 0.0 0.0 0.0 1.9 0.0 0.9 0.3 10.5 1.4 0.0 0.0 1171.8 0.0 0.0 5.6 0.0 0.9 0.0 0.1 0.0 0.0 0.1 8.4 1274.6 0.0 0.0 0.0 1.9 0.2 2.1 0.4 1.8 49.6 0.0 93.6 0.0 5497.5 221.3 0.3 0.0 1.5 0.1 0.1 0.0 0.7 0.0 99.7 0.0 2.0 0.7 0.3 0.5 0.0 0.0 0.0 0.0 2.3 0.0 0.0 LRRC59 "FLJ21675, PRO1855" ENSG00000108829 "Leucine rich repeat containing 59" Q96AG4 17 50375059-50397523 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 272.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030827, HPA030829" Enhanced Enhanced "Endoplasmic reticulum" NA NA 740000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA030827: AB_10602704, HPA030829: AB_10670045" "unprognostic (4.73e-2)" "unprognostic (2.15e-2)" "prognostic favorable (2.60e-4)" "unprognostic (5.63e-3)" "unprognostic (2.80e-1)" "prognostic unfavorable (1.00e-5)" "prognostic unfavorable (3.12e-6)" "unprognostic (1.88e-3)" "unprognostic (9.95e-2)" "unprognostic (5.62e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (3.68e-2)" "prognostic unfavorable (1.19e-6)" "unprognostic (2.77e-1)" "unprognostic (1.44e-1)" "unprognostic (3.39e-3)" "prognostic unfavorable (1.90e-5)" 49.6 82.6 18.5 54.1 20.5 79.3 34.1 18.4 21.7 60.4 19.0 72.1 46.8 32.2 55.5 47.9 29.4 32.2 33.0 19.1 18.6 41.1 75.0 45.8 30.9 18.2 19.3 21.7 119.4 34.8 21.8 51.7 18.6 35.3 72.0 21.7 56.2 35.7 32.6 24.3 46.0 52.3 18.3 33.0 73.8 29.2 22.0 29.3 36.0 17.0 42.8 56.6 30.1 19.9 390.5 289.9 81.8 123.6 135.3 158.7 146.2 310.7 172.3 284.5 249.4 668.8 109.0 168.8 207.8 356.4 174.3 138.1 205.2 265.2 336.3 90.4 298.6 295.9 154.8 361.8 283.7 294.1 134.8 140.8 211.3 305.2 351.7 82.6 213.3 95.7 278.9 155.6 189.4 264.3 209.0 139.0 92.5 364.2 419.1 175.9 261.9 323.6 156.0 194.9 199.1 165.4 107.5 119.3 161.9 120.4 201.1 157.9 229.6 327.4 135.5 306.2 410.4 232.3 205.1 213.6 222.2 195.9 210.8 22.8 21.9 19.8 9.4 26.9 11.7 11.0 9.5 11.5 20.3 8.5 6.1 7.9 10.9 8.6 27.8 16.5 10.3 13.0 18.5 20.5 18.4 21.7 19.1 18.6 18.2 19.3 18.6 18.3 22.0 19.9 33.1 22.4 23.7 5.2 61.2 139.4 102.1 54.7 43.9 20.4 55.0 30.9 4.1 40.0 50.0 20.2 2.1 90.8 38.4 101.6 29.4 165.0 67.1 53.6 53.8 45.6 38.3 36.6 5.5 187.0 272.2 64.5 104.5 96.3 30.4 28.9 27.1 69.1 103.3 21.9 5.5 178.3 26.4 29.0 111.1 18.7 35.4 45.1 65.8 3.7 45.6 26.5 30.9 2.0 6.8 187.7 75.7 29.0 211.3 164.8 63.5 48.0 26.5 15.5 13.1 59.1 92.8 61.3 27.7 66.1 132.7 236.0 33.2 38.3 127.1 146.7 LRRC70 "LOC100130733, SLRN" ENSG00000186105 "Leucine rich repeat containing 70" Q7Z2Q7 5 62578819-62581446 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 3.6;Endothelial cells: 4.9;Erythroid cells: 1.7;Fibroblasts: 1.8;granulocytes: 3.8;Hepatic stellate cells: 3.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "HUVEC TERT2: 17.6;TIME: 9.6" "Low region specificity" "Detected in all" HPA013409 Uncertain NA NA 17000 "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013409: AB_10601911" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (4.04e-1)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.17e-4)" "unprognostic (3.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.60e-1)" "unprognostic (2.19e-1)" "unprognostic (4.15e-1)" "unprognostic (7.40e-4)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" 4.7 0.8 0.5 1.4 0.4 3.6 4.7 0.5 1.2 3.9 0.6 1.4 0.8 1.9 1.0 1.7 3.3 3.6 1.8 0.4 0.4 1.9 1.4 1.9 1.9 0.7 0.8 2.9 0.9 1.2 1.4 4.6 0.6 2.0 1.4 1.0 1.2 0.5 0.7 2.7 1.4 3.4 0.6 4.1 1.1 1.7 0.5 1.0 4.0 0.6 0.7 1.7 2.8 0.8 0.2 0.0 0.2 0.1 0.5 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 17.6 0.3 0.2 0.7 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 9.6 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.5 0.4 0.5 1.2 0.4 0.4 0.7 0.8 0.6 0.6 0.5 0.8 3.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.1 0.1 4.9 0.0 1.7 0.0 0.0 0.0 1.8 0.0 0.1 3.8 0.1 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.4 0.3 0.0 0.3 0.0 0.0 0.0 LRRN3 "FIGLER5, FLJ11129, NLRR3" ENSG00000173114 "Leucine rich repeat neuronal 3" Q9H3W5 7 111091006-111125454 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.2;thyroid gland: 19.6" "Cell type enhanced" "Detected in many" "Astrocytes: 47.0;Bipolar cells: 29.2;Cardiomyocytes: 24.8;Excitatory neurons: 81.2;Inhibitory neurons: 46.5;Leydig cells: 56.2;Oligodendrocyte precursor cells: 61.3" "Group enriched" "Detected in many" 7 "glioma: 17.5;thyroid cancer: 4.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 32.5;naive CD8 T-cell: 30.9" "Lineage enriched" "Detected in single" 70 "T-cells: 32.5" "Cell line enhanced" "Detected in some" "AF22: 24.7;BJ: 14.7;BJ hTERT+: 31.0;GAMG: 15.6;SH-SY5Y: 43.9;SuSa: 13.6;T-47d: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043820, HPA046792" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA043820: AB_2678687, HPA046792: AB_2679810" "unprognostic (4.93e-2)" "unprognostic (4.55e-2)" "unprognostic (5.92e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-2)" "unprognostic (4.78e-3)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" "unprognostic (1.51e-1)" "unprognostic (5.84e-2)" "unprognostic (4.85e-3)" "unprognostic (1.08e-2)" "unprognostic (3.29e-4)" "unprognostic (1.37e-1)" "unprognostic (1.69e-1)" "unprognostic (1.29e-2)" "unprognostic (7.23e-2)" 7.2 23.2 11.9 1.2 12.8 0.6 1.7 10.4 14.7 2.5 4.3 0.9 0.4 0.5 2.3 1.3 0.7 1.0 8.0 11.9 10.4 0.4 2.2 7.5 3.0 6.8 8.5 6.3 0.9 0.2 3.0 5.8 8.6 2.6 1.0 6.3 1.2 4.9 4.1 0.3 1.4 0.4 7.7 1.4 0.4 14.9 13.2 10.5 19.6 0.5 3.6 0.8 0.9 8.9 0.0 0.1 24.7 3.1 11.2 4.8 0.1 14.7 31.0 1.4 1.2 0.0 0.0 0.1 0.0 0.0 15.6 0.1 1.5 0.0 3.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 12.3 0.1 0.0 0.1 0.1 6.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.0 43.9 0.0 0.0 0.0 13.6 24.3 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 2.7 2.0 0.0 0.1 32.5 30.9 0.2 0.0 0.1 0.0 0.4 6.1 11.9 12.8 10.4 14.7 11.9 10.4 6.8 8.5 8.6 7.7 13.2 8.9 0.8 0.0 4.3 47.0 0.8 0.0 0.0 0.0 0.0 29.2 0.6 0.8 24.8 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.2 1.1 0.3 0.5 1.2 1.8 0.0 81.2 0.0 0.5 13.3 1.5 0.5 1.3 0.0 1.1 0.0 0.8 3.3 46.5 0.0 0.0 0.0 0.4 4.4 56.2 0.2 1.8 7.5 0.8 11.0 1.0 61.3 7.0 0.0 0.0 16.1 0.0 0.0 0.0 0.1 0.0 3.8 0.0 1.6 1.7 1.1 0.4 0.0 0.1 0.4 10.3 0.5 0.0 0.2 LRRTM1 FLJ32082 ENSG00000162951 "Leucine rich repeat transmembrane neuronal 1" Q86UE6 2 80288351-80304752 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 22.4;salivary gland: 12.8" "Group enriched" "Detected in some" 4 "Endometrial stromal cells: 4.8;Excitatory neurons: 7.2;Inhibitory neurons: 13.2;Oligodendrocyte precursor cells: 10.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 11 "endometrial cancer: 8.8;ovarian cancer: 16.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SH-SY5Y: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046607, HPA062660" Approved Approved "Golgi apparatus" NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA046607: , HPA062660: AB_2684824" "unprognostic (2.47e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-3)" "unprognostic (5.63e-2)" "unprognostic (6.67e-2)" "unprognostic (4.35e-1)" "unprognostic (2.66e-1)" "unprognostic (8.16e-2)" "unprognostic (6.03e-3)" "unprognostic (7.10e-4)" "unprognostic (3.16e-2)" "unprognostic (1.90e-1)" "unprognostic (4.96e-4)" 0.5 0.9 6.4 0.3 13.4 0.0 0.1 0.0 10.0 2.2 0.0 3.7 0.6 0.6 0.3 0.3 1.2 0.2 1.3 16.3 5.2 0.3 0.4 0.1 0.0 0.9 9.4 0.3 0.1 0.0 1.9 0.0 2.0 1.0 0.3 0.4 12.8 1.2 0.0 0.1 1.3 0.3 0.2 0.0 0.7 0.2 22.4 0.0 1.6 0.1 0.0 0.6 0.8 4.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 13.4 0.0 10.0 16.3 5.2 0.9 9.4 2.0 0.2 22.4 4.6 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 1.3 1.0 4.8 0.3 0.0 0.0 7.2 0.7 0.0 0.1 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 10.6 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 6.6 0.0 0.9 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 LRRTM2 KIAA0416 ENSG00000146006 "Leucine rich repeat transmembrane neuronal 2" O43300 5 138868921-138875368 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 13.7;retina: 4.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.0;Excitatory neurons: 23.7;Glandular and luminal cells: 9.7;Inhibitory neurons: 24.3;Oligodendrocyte precursor cells: 28.1;Oligodendrocytes: 16.3" "Cancer enriched" "Detected in single" 11 "glioma: 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HDLM-2: 15.8;SCLC-21H: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" "unprognostic (1.77e-2)" "unprognostic (2.39e-1)" "unprognostic (1.48e-1)" "unprognostic (2.85e-1)" "unprognostic (3.58e-1)" "unprognostic (8.72e-2)" "unprognostic (4.31e-2)" "unprognostic (4.48e-1)" "unprognostic (4.47e-2)" "unprognostic (8.54e-2)" "unprognostic (1.13e-2)" "unprognostic (3.13e-2)" "unprognostic (2.86e-2)" "unprognostic (8.11e-2)" "unprognostic (1.08e-1)" "unprognostic (4.34e-2)" "unprognostic (1.05e-1)" 0.9 1.7 8.6 0.1 10.6 0.1 0.4 2.0 13.7 0.2 0.0 0.3 0.2 0.2 0.0 0.1 0.1 0.3 0.1 9.9 4.1 0.1 0.2 0.1 0.2 0.7 4.0 0.2 0.4 0.0 0.4 2.0 0.9 0.1 0.2 4.2 0.1 0.0 0.2 0.1 0.3 0.3 0.0 0.6 0.1 0.0 8.2 0.3 0.2 0.0 0.0 0.1 0.1 11.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.4 15.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 10.6 2.0 13.7 9.9 4.1 0.7 4.0 0.9 0.0 8.2 11.2 7.6 6.4 1.5 2.9 0.4 0.0 0.2 0.2 0.6 11.0 0.3 0.9 0.8 0.0 0.7 0.0 4.2 0.0 0.4 0.1 0.0 0.0 0.0 4.9 1.6 2.9 0.0 0.0 23.7 0.0 0.0 0.5 0.0 9.7 1.3 0.4 2.5 0.2 0.1 6.7 24.3 0.0 0.0 0.3 0.4 0.0 0.0 0.4 1.8 1.9 0.0 2.1 0.0 28.1 16.3 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 3.6 0.0 1.7 1.1 0.0 0.0 0.7 0.4 0.3 0.3 1.2 0.0 0.0 LRRTM4 FLJ12568 ENSG00000176204 "Leucine rich repeat transmembrane neuronal 4" Q86VH4 2 76747685-77593319 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 17.6;retina: 6.8" "Group enriched" "Detected in some" 16 "Excitatory neurons: 3972.6;Inhibitory neurons: 2310.6;Oligodendrocyte precursor cells: 3758.4" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 10 "Karpas-707: 125.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.00e-1)" "unprognostic (4.40e-2)" "unprognostic (3.13e-1)" "unprognostic (4.72e-4)" "unprognostic (7.20e-2)" "unprognostic (1.30e-1)" "unprognostic (1.27e-2)" "unprognostic (9.15e-2)" "unprognostic (3.93e-1)" "unprognostic (5.84e-2)" "unprognostic (4.22e-2)" "unprognostic (1.40e-1)" "unprognostic (2.64e-1)" "unprognostic (5.77e-3)" "unprognostic (3.54e-2)" "unprognostic (7.99e-2)" 0.4 0.6 5.8 0.3 11.4 1.7 0.2 0.1 17.6 0.4 0.0 0.5 0.8 0.4 1.5 0.8 0.2 0.7 0.1 13.5 1.6 0.2 1.3 0.8 0.4 0.2 4.1 0.6 0.5 0.0 1.0 0.9 1.2 0.6 0.5 6.8 0.9 1.5 1.6 0.8 0.5 0.3 0.0 0.5 0.6 0.3 0.0 0.1 0.7 0.3 0.2 0.3 0.5 14.5 1.4 1.7 0.9 0.8 0.0 0.0 0.9 0.3 0.0 0.0 0.0 2.1 0.5 1.0 2.2 0.8 0.7 0.8 0.2 0.0 0.3 0.8 2.5 0.5 4.8 3.1 0.4 1.3 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.5 125.8 0.0 2.8 0.5 0.7 12.2 0.2 1.2 0.5 0.1 2.6 0.0 4.1 3.7 1.4 0.8 0.7 0.8 2.0 1.4 0.9 0.0 2.9 3.7 0.1 0.2 0.0 2.4 0.1 2.8 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.5 0.2 0.1 0.0 0.1 0.0 5.8 11.4 0.1 17.6 13.5 1.6 0.2 4.1 1.2 0.0 0.0 14.5 0.0 0.0 0.5 208.6 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.3 0.3 0.0 0.0 0.0 4.2 0.1 0.0 0.0 0.0 0.0 1.1 0.4 0.2 0.4 0.0 0.0 3972.6 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.7 0.5 0.0 0.0 2310.6 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 84.3 0.0 2.8 0.0 3758.4 176.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.7 2.3 6.6 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LRTM2 ENSG00000166159 "Leucine rich repeats and transmembrane domains 2" Q8N967 12 1820267-1836753 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 11.8" "Group enriched" "Detected in some" 4 "Bipolar cells: 7.9;Excitatory neurons: 10.2;Horizontal cells: 11.8;Inhibitory neurons: 7.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 4.3;SCLC-21H: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA055094, HPA062745" Uncertain Approved Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 36: HEL - Hemostasis" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA055094: AB_2682693, HPA062745: " "unprognostic (1.84e-3)" "unprognostic (4.83e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (5.49e-2)" "unprognostic (1.60e-1)" "unprognostic (1.34e-3)" "unprognostic (2.25e-1)" "unprognostic (1.24e-1)" "unprognostic (6.20e-4)" "unprognostic (2.21e-1)" "unprognostic (8.02e-2)" 0.0 0.0 2.9 0.0 11.4 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 3.6 0.0 0.0 0.0 0.0 0.6 4.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 11.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 11.4 0.0 3.8 3.9 3.6 0.6 4.8 0.5 0.2 11.8 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 7.8 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Group enriched" "Detected in many" 11 "Hofbauer cells: 407.1;Kupffer cells: 1326.9;Langerhans cells: 1240.5;Macrophages: 871.6;monocytes: 1096.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 39.3;HMC-1: 73.6;MOLT-4: 39.6;NB-4: 76.2;THP-1: 179.9;U-937: 92.9" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" 15.2 10.2 4.3 22.0 4.3 100.3 7.9 4.6 7.2 5.6 5.0 7.9 7.1 3.7 1.4 5.5 6.6 3.1 7.6 4.6 5.5 10.8 14.4 48.8 13.8 6.1 4.9 3.0 4.7 0.9 6.1 4.7 6.6 8.9 3.0 0.5 6.9 2.3 2.1 7.8 15.0 5.1 5.4 181.9 5.7 1.8 5.2 15.1 4.6 1.9 7.1 9.1 5.1 6.0 0.3 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 2.5 0.6 0.0 0.0 0.5 0.3 0.4 0.3 12.9 0.0 39.3 0.0 0.0 0.7 29.3 73.6 0.0 0.3 0.1 1.2 0.3 0.9 0.8 0.1 0.2 0.0 0.0 39.6 76.2 0.1 0.0 0.0 18.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 179.9 0.3 0.0 0.4 0.0 0.2 0.1 0.0 5.9 0.0 92.9 0.0 112.2 419.7 681.6 9.4 1273.9 80.7 32.8 15.9 20.2 392.9 21.9 10.9 9.0 1133.0 21.6 1746.7 69.9 12.0 541.6 4.3 4.3 4.6 7.2 4.6 5.5 6.1 4.9 6.6 5.4 5.2 6.0 5.4 35.3 86.7 0.7 43.7 35.2 0.3 0.2 0.0 0.3 3.2 12.2 1.9 7.2 13.0 11.0 0.0 2.9 42.8 1.0 0.0 0.6 1.5 0.4 1.9 12.9 0.0 15.1 0.2 0.2 3.8 9.2 1.5 0.4 70.3 0.1 22.9 5.8 407.1 0.0 0.3 0.0 2.0 1326.9 1240.5 5.4 3.7 871.6 44.4 24.4 1096.6 0.7 60.8 0.5 0.1 0.1 1.1 1.2 4.7 1.0 0.0 3.8 11.0 0.2 26.3 2.2 2.8 2.4 4.6 0.4 28.3 5.3 43.6 0.0 0.4 0.3 LTA "LT, TNFB, TNFSF1" ENSG00000226979 "Lymphotoxin alpha" P01374 6 31572054-31574324 "Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 1.9;lymphoid tissue: 5.6;testis: 4.2" "Group enriched" "Detected in some" 4 "B-cells: 13.7;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.2;MOLT-4: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA007729 Uncertain "Secreted to blood" NA NA 8150 "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "HPA007729: AB_1852906" "unprognostic (3.76e-2)" "unprognostic (1.48e-2)" "unprognostic (1.36e-3)" "unprognostic (8.99e-5)" "unprognostic (3.22e-1)" "unprognostic (5.13e-3)" "unprognostic (2.07e-1)" "unprognostic (4.71e-2)" "unprognostic (3.10e-2)" "unprognostic (3.39e-4)" "unprognostic (2.68e-2)" "unprognostic (6.77e-2)" "unprognostic (8.72e-12)" "unprognostic (2.59e-1)" "unprognostic (5.49e-2)" "unprognostic (4.30e-2)" "unprognostic (3.03e-1)" 0.2 0.0 0.1 0.6 0.1 0.8 0.1 0.2 0.2 0.2 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.4 2.4 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.2 0.1 1.9 0.0 0.1 5.6 0.1 4.2 0.1 0.0 0.2 0.0 2.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.1 0.0 1.1 2.3 13.7 0.1 0.1 0.0 0.6 0.6 0.5 1.3 2.5 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.1 0.3 0.6 0.0 0.0 1.9 0.0 0.0 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.3 0.4 0.4 0.0 0.3 0.0 1.0 0.4 0.0 1.0 2.5 2.4 0.1 0.0 0.4 0.5 0.1 0.0 0.1 0.0 0.3 0.0 0.5 0.3 1.8 0.5 0.5 0.4 0.0 14.5 0.1 0.0 0.0 LTB "p33, TNFC, TNFSF3" ENSG00000227507 "Lymphotoxin beta" Q06643 6 31580525-31582522 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 66.7;lymphoid tissue: 229.2" "Cell type enhanced" "Detected in many" "B-cells: 1087.8;dendritic cells: 183.5;Ductal cells: 280.4;Pancreatic endocrine cells: 296.2;T-cells: 554.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.6;Daudi: 127.4;HDLM-2: 82.2;HMC-1: 38.1;NB-4: 62.3;REH: 58.6;U-698: 90.8" "Not detected" "Not detected" HPA048884 Approved Approved Centrosome NA NA "Cluster 30: Non-specific - Translation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA048884: AB_2680543" "unprognostic (1.43e-2)" "unprognostic (3.89e-2)" "unprognostic (7.29e-2)" "prognostic favorable (2.36e-6)" "unprognostic (2.91e-3)" "prognostic favorable (1.74e-4)" "unprognostic (1.45e-1)" "unprognostic (9.49e-3)" "unprognostic (1.42e-3)" "unprognostic (4.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (8.91e-2)" "unprognostic (4.92e-2)" "unprognostic (6.56e-3)" "unprognostic (1.99e-1)" 3.5 0.7 0.2 82.6 0.3 19.1 1.3 0.1 0.5 1.3 0.2 6.7 8.2 1.2 0.0 4.3 1.2 4.8 1.1 0.1 0.2 10.3 4.8 8.7 103.9 0.4 0.2 0.4 2.5 0.2 0.7 0.9 0.3 2.4 2.7 0.0 4.2 0.3 1.0 2.2 66.7 1.9 0.2 229.2 13.9 0.2 0.3 83.3 3.8 1.4 47.6 8.7 1.4 0.2 18.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 35.6 127.4 1.8 0.0 0.2 0.0 0.0 0.0 0.0 82.2 0.0 1.4 0.0 0.0 0.0 0.4 38.1 0.0 0.0 0.0 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.0 18.5 62.3 0.0 0.0 0.0 58.6 0.0 11.4 32.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.7 0.0 0.0 0.5 0.0 0.0 0.0 0.8 90.8 0.0 0.0 0.0 79.2 9.2 542.5 95.7 55.9 646.7 1027.3 924.3 419.4 14.5 1021.9 713.6 317.0 327.8 142.5 94.5 412.0 672.0 308.9 0.2 0.3 0.1 0.5 0.1 0.2 0.4 0.2 0.3 0.2 0.3 0.2 3.0 0.0 9.0 1.3 1087.8 16.3 0.5 45.7 2.2 0.7 2.9 3.7 0.5 2.8 4.7 90.1 0.0 0.9 183.5 0.9 1.9 280.4 3.5 2.2 2.0 8.4 0.0 11.2 0.9 113.1 0.3 6.3 3.1 1.5 14.0 0.1 10.8 3.5 10.1 0.0 0.9 0.4 160.7 31.0 112.1 0.2 0.6 49.8 42.7 0.0 72.3 1.8 99.9 0.0 0.3 296.2 1.6 0.0 13.6 3.0 0.0 11.6 0.9 0.2 6.6 1.3 4.3 0.4 1.2 1.2 12.4 0.3 554.0 0.3 3.6 0.3 LTBP1 ENSG00000049323 "Latent transforming growth factor beta binding protein 1" Q14766 2 32946953-33399509 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 161.4" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Fibroblasts: 116.1;Leydig cells: 90.4;Peritubular cells: 161.0;Skeletal myocytes: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 569.4;HSkMC: 185.3;HUVEC TERT2: 194.5;U-2197: 181.1;U-87 MG: 255.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB025428 Approved "Secreted to extracellular matrix" NA NA 96000000 "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025428: " "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (5.29e-2)" "unprognostic (6.23e-2)" "unprognostic (3.11e-3)" "unprognostic (1.83e-1)" "unprognostic (1.06e-3)" "unprognostic (5.67e-2)" "unprognostic (7.48e-2)" "unprognostic (1.14e-1)" "unprognostic (9.96e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.79e-6)" "unprognostic (4.61e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.62e-4)" 22.9 13.1 7.8 22.1 9.4 11.5 14.5 7.1 7.5 161.4 10.5 27.2 10.2 58.9 37.8 21.2 37.0 73.0 89.0 8.8 9.1 38.6 18.6 27.5 6.9 12.1 10.6 30.2 7.9 2.4 9.0 73.2 9.2 46.9 16.5 0.7 14.6 73.6 15.7 10.8 15.0 96.7 9.1 8.3 32.8 17.9 8.8 8.2 6.5 28.4 18.7 53.9 28.3 13.4 0.3 12.5 31.3 0.3 26.1 569.4 13.5 46.5 95.7 6.4 9.3 25.3 4.6 41.3 1.0 6.0 8.8 2.4 0.7 1.5 22.0 0.6 15.3 135.6 15.0 4.1 118.6 0.5 15.7 185.3 4.4 141.2 6.9 61.8 194.5 6.3 8.7 0.3 51.1 19.9 5.5 0.2 22.4 1.0 39.2 4.7 65.8 0.6 0.4 22.4 6.3 3.4 9.5 72.1 0.8 49.1 27.9 0.4 126.4 6.4 26.2 181.1 37.6 74.8 80.0 58.8 255.9 5.2 10.8 3.1 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 5.3 7.8 9.4 7.1 7.5 8.8 9.1 12.1 10.6 9.2 9.1 8.8 13.4 33.6 0.0 0.6 108.4 0.4 13.5 5.6 13.0 10.2 0.0 6.9 6.6 80.9 4.3 3.6 1.8 0.0 45.2 0.3 12.9 0.0 9.6 6.3 7.3 18.3 28.1 1.2 30.3 30.4 6.5 23.4 116.1 10.2 10.5 0.0 11.8 20.3 11.0 7.6 0.0 54.3 2.8 2.0 0.3 18.1 7.1 90.4 12.0 19.6 39.4 0.4 0.2 0.0 70.4 52.4 19.1 3.3 161.0 1.3 19.1 0.7 0.3 6.3 0.3 59.2 85.8 67.9 0.7 11.9 6.9 9.8 43.5 2.0 2.6 4.1 33.4 LTBP2 "C14orf141, LTBP3" ENSG00000119681 "Latent transforming growth factor beta binding protein 2" Q14767 14 74498183-74612378 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Heparin-binding" "Disease variant, Dwarfism, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 60.6;Fibroblasts: 59.5;Peritubular cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 240.8;HUVEC TERT2: 129.1;LHCN-M2: 129.4;TIME: 564.5" "Group enriched" "Detected in some" 10 "cerebellum: 5.3;olfactory bulb: 2.4" "Region enhanced" "Detected in many" "olfactory bulb: 15.4" HPA003415 Approved Approved Nucleoplasm "Secreted to extracellular matrix" NA NA 14000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA003415: AB_1079284" "unprognostic (1.24e-1)" "unprognostic (3.09e-2)" "unprognostic (5.10e-2)" "unprognostic (3.92e-3)" "unprognostic (2.08e-3)" "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (4.43e-2)" "unprognostic (1.08e-1)" "unprognostic (1.61e-1)" "unprognostic (2.80e-2)" "unprognostic (3.77e-1)" "unprognostic (1.98e-3)" "unprognostic (2.22e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.94e-4)" 34.2 4.0 1.1 15.2 2.9 0.6 24.4 4.1 5.6 66.2 9.5 6.6 3.1 22.5 23.9 10.7 11.7 33.1 45.4 1.2 1.1 4.1 2.1 64.9 8.3 2.2 1.1 39.4 8.7 9.6 7.3 28.0 1.4 15.7 2.6 2.3 26.7 19.6 13.6 12.6 6.9 16.0 2.2 3.9 8.5 5.4 1.9 3.1 53.0 21.4 6.1 14.2 21.6 1.0 2.5 4.9 1.2 0.2 36.9 67.7 0.2 47.4 16.2 9.2 5.7 0.0 17.4 0.4 13.8 240.8 4.1 4.8 0.2 17.7 3.8 0.2 0.8 0.8 2.2 2.1 8.8 0.1 0.6 70.2 7.7 50.7 29.1 68.9 129.1 0.1 0.2 0.1 129.4 1.1 0.1 0.3 0.3 0.2 4.5 0.5 1.1 0.1 11.3 6.7 1.0 3.3 33.1 0.1 1.1 3.4 1.1 0.2 564.5 3.3 54.0 17.0 18.0 0.7 0.7 0.1 13.1 0.3 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 2.9 4.1 5.6 1.2 1.1 2.2 1.1 1.4 2.2 1.9 1.0 3.8 0.0 2.2 2.3 0.1 5.6 15.1 13.0 13.1 2.1 1.9 60.6 6.4 0.0 6.1 0.0 0.0 0.5 1.2 0.1 5.9 1.4 1.2 0.5 7.9 6.5 0.0 5.7 1.1 0.4 0.3 59.5 1.5 0.9 1.3 1.9 9.3 0.4 4.2 3.3 0.7 0.0 20.3 0.3 5.8 5.8 16.4 3.7 0.0 22.5 0.1 0.4 0.0 1.0 0.3 4.4 0.0 82.4 0.3 10.7 0.0 0.0 0.3 1.0 6.6 3.2 10.8 2.8 3.8 5.2 1.0 1.2 0.9 2.2 0.1 2.1 LTBP3 LTBP2 ENSG00000168056 "Latent transforming growth factor beta binding protein 3" Q9NS15 11 65538559-65558930 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 61.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 293.8;U-87 MG: 157.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (8.50e-3)" "unprognostic (4.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.24e-2)" "unprognostic (9.22e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-2)" "unprognostic (1.04e-2)" "unprognostic (4.52e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.24e-2)" 65.4 80.1 44.0 21.4 46.1 11.2 68.0 42.0 56.1 120.0 42.2 103.7 16.8 130.8 36.7 36.7 112.6 39.9 131.2 37.6 41.4 84.5 48.8 72.2 24.7 57.0 49.0 155.5 70.1 44.7 111.0 25.5 45.4 109.0 8.5 12.8 64.2 56.3 54.6 39.6 55.8 35.7 51.7 58.1 62.0 20.3 46.9 17.6 114.0 31.0 12.1 84.9 88.0 54.0 16.5 65.9 8.7 43.2 60.7 97.0 8.5 64.7 43.6 8.2 5.3 25.3 85.5 2.0 53.6 64.2 20.4 71.9 11.8 12.2 3.7 9.5 26.4 15.9 25.2 26.2 40.3 2.2 13.4 109.9 4.9 12.1 1.5 293.8 31.9 5.2 4.9 12.7 6.0 39.4 10.9 5.9 7.6 14.6 81.2 29.3 1.1 32.1 6.7 5.5 2.9 41.8 17.3 24.9 35.3 3.7 46.0 5.8 107.0 24.8 32.2 42.5 17.6 13.9 27.1 1.4 157.8 2.6 52.3 0.2 7.3 2.9 8.8 11.2 14.1 61.2 12.6 10.4 8.9 47.6 10.5 11.2 2.9 10.8 13.2 17.8 14.2 7.8 44.0 46.1 42.0 56.1 37.6 41.4 57.0 49.0 45.4 51.7 46.9 54.0 47.1 12.8 11.7 64.0 26.8 73.8 27.7 22.0 50.7 55.7 42.2 43.1 16.7 35.8 16.2 40.5 2.1 24.7 24.4 19.7 21.5 28.1 1.1 19.3 37.5 29.8 30.6 11.2 21.3 12.0 10.5 86.1 14.8 25.3 24.1 92.5 37.5 61.6 20.7 28.6 17.9 15.1 8.2 11.0 34.4 4.3 86.6 14.6 30.2 17.8 11.5 71.4 24.7 29.7 20.2 18.1 15.0 123.8 20.9 35.8 25.3 15.7 8.2 14.3 39.5 89.4 44.0 9.5 37.5 46.9 79.3 16.3 24.4 26.0 20.4 26.5 LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 327.1;Leydig cells: 972.3;Peritubular cells: 624.4;Skeletal myocytes: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 120.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" 138.5 48.5 11.3 22.3 10.9 8.3 98.8 1.7 13.3 334.6 9.6 144.5 59.2 309.6 44.7 100.6 246.8 39.3 401.9 10.7 14.2 64.7 37.4 242.5 24.8 16.2 10.3 315.2 37.2 22.6 75.9 38.3 16.4 253.6 38.2 3.7 82.8 126.3 63.0 73.0 135.4 74.4 11.3 80.5 125.3 78.5 14.2 12.9 173.2 156.7 14.0 188.6 374.5 15.3 19.8 21.3 41.7 56.5 15.1 16.0 6.6 7.7 24.9 7.8 6.4 6.4 43.8 22.4 34.9 13.1 12.4 26.3 10.6 26.8 2.6 61.0 3.3 7.3 53.7 2.4 49.4 3.0 23.1 19.9 21.7 15.6 27.8 41.0 4.9 21.6 46.7 120.3 1.9 19.7 3.1 1.3 4.9 56.1 24.9 51.9 1.1 35.6 3.9 1.7 1.8 17.4 28.3 21.5 7.4 6.4 11.9 11.3 20.4 1.3 81.4 2.6 16.7 26.8 24.9 7.1 35.1 28.5 20.4 0.0 1.5 0.4 8.1 2.4 5.5 3.5 7.7 6.5 2.7 2.0 3.2 3.4 0.3 3.0 1.3 5.0 5.5 2.3 11.3 10.9 1.7 13.3 10.7 14.2 16.2 10.3 16.4 11.3 14.2 15.3 84.7 6.4 14.1 2.0 11.6 57.6 30.9 62.8 56.3 60.4 13.0 18.2 15.5 17.2 18.5 22.0 0.0 1.5 12.7 38.2 1.9 6.3 11.1 14.8 154.7 29.9 4.2 12.4 8.1 4.7 2.6 327.1 37.2 24.2 10.2 13.5 102.4 3.3 7.5 40.4 11.3 42.2 6.1 6.4 39.6 39.0 972.3 13.9 58.7 15.0 9.5 3.5 16.5 2.0 14.0 6.9 16.6 624.4 16.5 23.6 97.7 0.3 7.1 3.2 59.2 229.2 52.8 50.7 36.3 38.2 29.1 2.6 24.9 10.2 36.4 27.2 LTBR "D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3" ENSG00000111321 "Lymphotoxin beta receptor" P36941 12 6375045-6391571 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 71.3;intermediate monocyte: 66.3;myeloid DC: 49.8;neutrophil: 45.0;non-classical monocyte: 50.1" "Group enriched" "Detected in many" 36 "dendritic cells: 49.8;granulocytes: 45.0;monocytes: 71.3" "Cell line enhanced" "Detected in many" "HHSteC: 393.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026202, HPA061617" Uncertain Supported "Golgi apparatus" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus" "CAB026202: , HPA061617: AB_2732666" "unprognostic (2.60e-2)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.23e-2)" "unprognostic (3.01e-2)" "unprognostic (3.24e-3)" "prognostic unfavorable (5.13e-4)" "unprognostic (2.08e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (3.66e-2)" "unprognostic (9.84e-3)" "unprognostic (6.91e-2)" "unprognostic (2.86e-1)" 67.6 64.4 13.9 36.4 14.6 11.7 60.3 14.7 15.9 65.8 18.0 72.7 48.6 68.1 20.7 81.3 49.6 48.3 37.2 13.3 15.8 55.1 135.8 66.0 14.6 19.6 17.3 46.3 78.7 54.9 26.3 48.6 18.8 61.9 34.3 1.9 61.5 44.0 26.3 75.1 51.1 62.6 17.4 44.8 67.7 13.3 18.1 11.7 57.2 23.5 18.0 65.8 65.1 17.0 98.2 130.3 0.0 41.1 245.9 183.7 89.9 67.9 153.1 98.8 101.1 62.0 148.7 0.1 39.5 145.7 0.5 112.2 0.5 140.5 38.9 0.0 0.2 58.1 53.2 36.6 393.1 4.1 94.6 270.8 255.2 70.7 197.1 102.6 91.2 0.0 55.5 0.5 115.0 93.5 0.4 29.3 1.2 155.7 74.4 0.0 6.6 0.2 149.2 112.2 0.7 0.5 63.6 122.9 143.6 5.0 20.5 105.3 58.0 34.6 39.6 129.0 72.1 0.0 0.4 0.1 14.6 35.9 129.5 5.4 71.3 0.5 0.2 66.3 0.0 0.1 0.1 0.1 49.8 0.1 0.3 0.2 45.0 1.5 50.1 11.8 0.1 27.2 13.9 14.6 14.7 15.9 13.3 15.8 19.6 17.3 18.8 17.4 18.1 17.0 47.0 60.9 68.9 2.9 3.6 39.0 87.2 46.4 72.3 4.1 33.9 35.9 15.5 45.8 60.7 31.3 0.0 31.3 12.4 78.3 9.8 52.2 0.7 23.8 48.6 49.3 52.0 15.8 0.5 99.8 43.6 50.5 89.7 45.2 29.7 30.1 50.7 66.5 48.7 0.0 0.5 57.1 34.6 77.3 34.6 5.1 52.8 50.8 23.2 14.0 43.1 9.6 11.3 5.5 1.1 69.5 82.3 39.9 3.3 110.7 136.9 30.1 42.8 1.6 26.3 33.1 42.0 1.6 0.9 78.9 61.7 37.5 4.9 28.0 63.4 97.6 LTF HLF2 ENSG00000012223 Lactotransferrin P02788 3 46435645-46485234 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Ion transport, Iron transport, Osteogenesis, Transcription, Transcription regulation, Transport" "Antibiotic, Antimicrobial, DNA-binding, Heparin-binding, Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 4255.5;salivary gland: 1162.5" "Cell type enriched" "Detected in many" 5 "Breast glandular cells: 1519.6" "Group enriched" "Detected in all" 5 "breast cancer: 239.0;endometrial cancer: 170.3;glioma: 152.6;prostate cancer: 195.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 23 "neutrophil: 5.4;non-classical monocyte: 17.0" "Group enriched" "Detected in many" 23 "granulocytes: 5.4;monocytes: 17.0" "Group enriched" "Detected in some" 11 "RPMI-8226: 43.2;TIME: 14.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB008646, CAB016201, HPA057177, HPA059976" Enhanced "Secreted to blood" NA NA 350000000 "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" "CAB008646: AB_1618695, CAB016201: AB_629860, HPA057177: AB_2683361, HPA059976: AB_2684185" "unprognostic (7.24e-3)" "unprognostic (2.43e-1)" "unprognostic (5.94e-2)" "unprognostic (3.41e-2)" "unprognostic (7.14e-3)" "unprognostic (3.45e-2)" "unprognostic (6.43e-3)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" "unprognostic (4.21e-2)" "unprognostic (3.43e-1)" "unprognostic (1.04e-1)" "prognostic favorable (6.30e-5)" "unprognostic (1.66e-2)" "unprognostic (3.53e-1)" "unprognostic (2.05e-1)" "unprognostic (9.09e-3)" 6.9 1.2 2.5 36.1 3.4 4255.5 333.3 4.6 4.2 658.3 2.2 2.8 1.2 4.1 157.5 23.0 4.3 7.5 5.7 3.7 6.2 105.3 3.3 29.4 8.6 4.8 21.5 0.5 18.6 6.2 7.0 3.1 12.6 154.2 2.2 0.9 1162.5 378.9 1.7 11.8 5.1 1.9 7.1 70.5 331.6 0.4 14.5 29.8 10.1 1.6 345.7 2.4 1.2 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 1.9 0.5 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.7 0.1 0.1 0.0 0.1 0.6 43.2 0.2 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 14.3 0.0 0.3 1.2 0.1 0.6 0.0 0.1 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 17.0 0.4 0.0 29.5 2.5 3.4 4.6 4.2 3.7 6.2 4.8 21.5 12.6 7.1 14.5 9.9 15.5 0.0 2.8 0.7 4.3 1.1 8.6 82.8 0.0 0.0 1519.6 198.4 1.0 2.8 298.0 71.7 0.0 0.0 6.2 0.1 0.0 1.4 1.2 0.3 0.2 8.8 0.0 3.0 0.1 0.9 0.2 2.5 56.1 2.3 1.3 0.1 5.0 0.0 0.0 0.0 0.0 0.2 14.2 0.0 0.7 1.5 5.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.1 78.6 0.0 18.6 14.9 0.0 0.0 0.3 9.9 0.2 0.1 15.4 0.1 0.1 4.0 0.1 0.1 101.7 LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503637-41513887 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.2;lung: 15.1;salivary gland: 11.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 25.3;Gastric mucus-secreting cells: 18.8;Hepatic stellate cells: 11.4;Intestinal goblet cells: 7.9;Proximal enterocytes: 15.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "MAIT T-cell: 5.7;plasmacytoid DC: 5.0" "Group enriched" "Detected in many" 10 "dendritic cells: 5.0;T-cells: 5.7" "Cell line enhanced" "Detected in some" "HEL: 5.0;NB-4: 9.7;RH-30: 4.6;THP-1: 14.7" "Low region specificity" "Detected in many" HPA059545 Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA059545: AB_2684057" "unprognostic (9.47e-4)" "unprognostic (5.52e-4)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-1)" "unprognostic (5.65e-3)" "unprognostic (1.74e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.81e-3)" "unprognostic (9.36e-3)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" 0.8 0.6 1.0 1.4 1.6 4.6 0.5 1.2 1.8 0.9 0.6 5.2 12.5 0.2 0.0 0.3 0.4 2.4 1.7 1.3 0.7 4.0 2.9 15.1 1.2 0.6 0.6 0.1 0.3 0.6 0.7 10.4 0.7 0.4 5.7 0.1 11.8 0.3 1.8 1.4 13.2 0.3 0.6 5.5 9.9 2.5 0.8 0.4 0.7 0.0 2.1 0.7 0.7 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.6 0.8 1.2 2.2 0.0 0.0 0.0 0.6 0.0 0.0 2.6 0.0 0.4 0.2 1.3 5.0 0.1 0.0 2.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 1.9 0.0 1.8 0.0 0.0 9.7 0.4 1.8 0.2 0.2 4.6 0.1 0.0 0.0 0.4 2.9 0.1 0.2 0.0 2.6 0.2 14.7 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.8 0.0 0.0 0.0 0.4 0.0 5.7 0.5 0.3 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 1.0 1.6 1.2 1.8 1.3 0.7 0.6 0.6 0.7 0.6 0.8 0.9 0.3 0.0 0.0 0.3 1.6 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.8 2.8 0.9 0.0 0.0 0.3 5.5 25.3 0.0 0.0 2.8 0.1 0.4 1.8 1.8 3.2 2.9 0.2 1.5 0.2 18.8 0.2 0.0 0.3 11.4 0.5 0.1 0.0 0.2 7.9 0.0 1.9 0.6 2.1 0.0 0.4 3.6 0.0 0.4 0.0 1.0 0.5 0.4 0.7 5.5 0.0 2.7 0.0 15.3 0.0 5.6 0.0 0.0 0.3 0.5 2.2 1.2 0.0 0.1 0.4 4.0 0.0 3.8 0.0 LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 966.4;Fibroblasts: 2136.1;Leydig cells: 401.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 1991.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" 161.5 133.5 0.6 68.1 0.7 0.3 153.2 0.6 5.6 199.8 4.2 85.0 56.1 301.0 88.3 75.7 59.2 739.0 183.8 0.7 0.9 85.0 34.6 211.4 41.3 0.9 0.8 92.9 72.9 26.3 5.3 535.9 0.8 115.2 133.0 5.7 14.3 67.4 9.6 20.0 90.6 354.5 0.7 4.8 47.1 17.5 1.3 13.4 30.8 73.0 80.3 486.0 39.2 0.8 0.0 0.3 6.9 0.0 237.4 115.9 0.7 400.8 1991.0 16.0 24.3 0.0 0.1 0.0 0.0 339.9 0.0 0.6 0.0 0.0 5.4 0.0 0.0 0.0 21.5 0.0 183.7 0.6 0.1 160.5 0.0 33.7 1.0 0.9 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.6 1.2 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.3 14.9 0.1 0.0 10.8 16.3 0.0 0.0 0.0 17.0 4.5 14.3 0.0 0.2 0.0 0.0 8.8 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.6 5.6 0.7 0.9 0.9 0.8 0.8 0.7 1.3 0.8 77.5 12.8 30.9 0.0 0.6 97.6 1.2 0.8 3.4 0.2 9.4 8.6 15.2 0.0 5.0 0.0 2.1 44.9 4.0 0.1 0.0 0.7 3.5 27.0 966.4 27.2 0.0 0.0 0.0 0.0 38.9 2136.1 8.6 15.2 18.3 0.0 55.0 0.3 63.6 0.0 0.2 0.3 0.0 0.3 143.5 8.7 401.7 9.5 117.4 16.9 1.0 86.9 0.0 0.0 0.0 2.1 0.0 44.8 6.3 4.9 0.4 0.3 0.8 3.0 0.0 39.1 165.5 0.2 0.9 5.9 100.2 84.0 14.5 27.4 0.0 4.1 LUZP2 ENSG00000187398 "Leucine zipper protein 2" Q86TE4 11 24496970-25082638 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 30.6" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 1890.0" "Group enriched" "Detected in some" 7 "glioma: 3.5;prostate cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 10.9;HAP1: 4.4;HeLa: 1.9;hTERT-RPE1: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039007, HPA046161" Enhanced Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA039007: AB_2676307, HPA046161: AB_2679564" "unprognostic (4.49e-2)" "unprognostic (2.74e-2)" "unprognostic (8.63e-2)" "unprognostic (3.50e-1)" "unprognostic (5.22e-3)" "unprognostic (3.38e-1)" "unprognostic (4.88e-2)" "unprognostic (5.67e-4)" "unprognostic (2.40e-1)" "unprognostic (5.66e-2)" "unprognostic (6.16e-3)" "unprognostic (4.09e-2)" "unprognostic (5.18e-3)" "unprognostic (9.41e-3)" "unprognostic (4.18e-2)" "unprognostic (2.17e-1)" "unprognostic (9.64e-2)" 0.3 6.5 8.6 0.1 8.5 0.1 0.5 11.8 8.0 0.1 1.1 0.8 0.1 0.2 0.0 0.1 0.0 0.1 0.1 6.3 15.1 0.2 0.9 0.2 0.0 10.8 30.6 0.0 0.0 0.0 0.6 0.0 17.2 2.4 0.6 1.1 0.1 0.1 0.0 0.1 0.2 0.3 17.6 0.1 0.1 0.5 15.3 0.0 0.0 0.6 0.0 0.3 0.1 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.9 4.4 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.2 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 8.5 11.8 8.0 6.3 15.1 10.8 30.6 17.2 17.6 15.3 16.5 0.3 0.0 0.0 11.4 0.0 0.6 0.1 0.0 1.8 6.9 0.3 1.7 0.6 0.0 0.0 3.7 0.0 0.0 0.1 1.2 0.0 0.0 33.7 0.6 0.7 0.1 0.0 0.0 149.4 0.0 0.1 2.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 371.4 1.7 0.0 0.0 0.0 6.4 0.9 0.1 0.0 4.7 0.0 0.3 0.0 1890.0 9.1 0.2 23.9 0.0 0.0 4.5 0.0 0.7 0.0 0.8 0.0 0.4 0.3 0.3 0.6 0.9 0.3 0.1 0.0 2.4 1.5 1.6 LVRN "APQ, AQPEP, FLJ90650, TAQPEP" ENSG00000172901 Laeverin Q6Q4G3 5 115962454-116027619 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adipose tissue: 11.1;placenta: 21.8" "Group enriched" "Detected in some" 4 "Early spermatids: 29.3;Extravillous trophoblasts: 33.1;Late spermatids: 68.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "spinal cord: 2.5" HPA053254 Enhanced "Intracellular and membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 50: Fibroblasts - ECM organization" "HPA053254: AB_2682092" "unprognostic (1.47e-1)" "unprognostic (3.38e-3)" "unprognostic (5.81e-2)" "unprognostic (2.97e-3)" "unprognostic (5.38e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-3)" "unprognostic (1.88e-2)" "unprognostic (2.23e-1)" "unprognostic (2.23e-2)" "unprognostic (3.83e-3)" "unprognostic (1.22e-1)" "unprognostic (1.67e-7)" "unprognostic (1.05e-2)" "unprognostic (5.94e-2)" "unprognostic (6.53e-2)" "unprognostic (3.31e-2)" 11.1 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 21.8 0.0 0.0 0.4 0.0 0.2 0.1 0.3 0.4 0.8 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 1.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 29.3 0.0 0.1 0.1 0.0 0.0 2.1 0.0 33.1 7.9 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.8 0.0 0.0 0.0 0.0 68.1 4.7 0.3 0.0 1.9 0.0 0.0 0.0 3.0 1.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.3 0.3 0.1 0.0 10.7 0.0 1.0 0.0 0.1 LY6E "RIG-E, SCA-2, TSA-1" ENSG00000160932 "Lymphocyte antigen 6 family member E" Q16553 8 143017982-143023832 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 614.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1386.5;Extravillous trophoblasts: 4724.2;Granulosa cells: 998.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 753.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 627.1;BJ hTERT+ SV40 Large T+ RasG12V: 888.7;MCF7: 878.7" "Intracellular and membrane" NA NA 44000 "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.05e-1)" "unprognostic (8.80e-2)" "unprognostic (3.88e-2)" "unprognostic (3.70e-3)" "unprognostic (9.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" "unprognostic (6.64e-2)" "unprognostic (4.94e-1)" "unprognostic (7.34e-2)" "unprognostic (1.74e-3)" "unprognostic (1.71e-2)" "prognostic unfavorable (6.74e-8)" "unprognostic (2.68e-1)" "unprognostic (2.28e-3)" "unprognostic (1.84e-3)" "unprognostic (2.12e-2)" 221.7 248.1 95.6 47.9 99.3 120.5 205.6 94.4 133.8 218.1 89.1 80.1 24.8 143.5 36.9 187.1 157.0 85.9 141.1 117.3 92.8 214.6 614.0 232.2 40.6 101.0 89.9 199.3 58.4 23.1 92.5 88.8 92.1 143.1 15.3 4.8 140.4 47.3 38.4 130.2 79.0 50.2 103.5 218.3 72.7 52.4 96.3 56.5 94.7 37.6 30.3 107.6 159.2 91.8 75.8 114.5 2.4 98.9 147.9 267.8 161.4 174.7 504.5 627.1 888.7 1.8 204.3 19.2 122.0 214.8 75.1 216.2 60.2 102.7 72.5 13.4 17.9 76.0 54.1 75.5 106.3 7.0 45.0 230.3 37.4 96.1 42.3 68.5 37.9 32.2 17.9 248.8 45.1 878.7 49.0 56.9 41.0 439.2 34.5 32.2 0.8 98.4 153.8 82.3 94.8 12.8 142.3 216.1 231.9 96.3 236.8 44.7 7.2 26.9 66.4 73.9 0.9 1.0 4.7 1.9 56.6 27.4 96.7 14.0 124.4 15.4 186.5 565.5 71.2 129.5 137.1 123.6 72.8 160.1 75.8 125.7 34.8 272.7 753.3 7.6 121.3 241.1 95.6 99.3 94.4 133.8 117.3 92.8 101.0 89.9 92.1 103.5 96.3 91.8 318.1 22.4 13.4 3.3 141.6 175.5 427.7 528.1 255.6 8.7 301.7 492.0 4.5 255.9 440.5 46.0 0.0 1386.5 149.6 2.4 23.5 298.8 3.8 13.5 233.3 312.0 29.3 76.6 21.4 22.7 4724.2 295.8 43.3 18.9 53.3 998.5 151.0 314.0 365.9 47.1 13.1 20.1 130.2 104.3 225.3 10.0 289.8 176.4 158.3 26.2 111.5 18.7 436.7 5.5 3.6 196.8 0.6 222.3 121.6 240.5 2.0 212.3 112.8 3.6 144.7 34.9 151.6 1.5 45.1 238.6 117.3 534.3 229.6 99.8 14.4 593.7 LY6G5B "C6orf19, G5b" ENSG00000240053 "Lymphocyte antigen 6 family member G5B" Q8NDX9 6 31670167-31673776 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" HPA048307 Approved "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA048307: AB_2680348" "unprognostic (2.69e-2)" "unprognostic (1.52e-1)" "unprognostic (8.53e-2)" "unprognostic (1.44e-2)" "unprognostic (5.80e-2)" "unprognostic (9.85e-3)" "unprognostic (5.04e-3)" "unprognostic (8.34e-3)" "unprognostic (5.45e-2)" "unprognostic (1.21e-1)" "unprognostic (1.58e-4)" "unprognostic (7.27e-3)" "unprognostic (1.98e-5)" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" "unprognostic (3.00e-2)" "unprognostic (3.98e-4)" 30.1 13.5 3.0 9.5 3.4 29.9 25.9 7.4 7.2 26.3 3.1 25.6 6.9 24.9 11.1 15.8 25.0 6.3 15.0 3.2 3.9 15.5 15.0 27.8 12.1 3.5 3.3 33.2 14.5 2.8 20.8 8.2 3.6 22.1 11.4 11.3 20.3 7.4 15.4 44.6 27.8 9.4 2.7 30.6 19.2 13.0 3.8 7.7 24.7 3.3 13.1 21.1 20.4 3.7 5.4 5.8 11.4 15.5 2.6 5.5 14.5 10.4 3.3 7.3 7.2 7.1 6.8 12.9 2.8 13.0 4.7 8.6 2.7 13.7 11.6 5.2 18.0 12.4 8.1 5.7 2.2 15.6 9.9 11.8 7.9 10.7 5.0 10.3 3.9 9.7 7.7 7.8 5.0 4.9 8.4 12.0 6.4 1.5 2.6 11.8 3.5 5.7 3.4 14.7 8.0 12.9 4.7 1.8 3.6 13.9 4.7 10.3 7.6 14.2 7.5 6.6 2.6 13.6 10.1 11.5 5.1 14.6 4.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.4 7.4 7.2 3.2 3.9 3.5 3.3 3.6 2.7 3.8 3.7 0.3 3.2 0.0 0.0 1.4 1.0 1.2 0.7 0.0 1.1 0.7 0.3 0.1 1.5 0.2 0.0 0.0 0.4 0.8 0.6 0.0 0.1 0.0 0.4 0.8 0.5 1.2 0.0 0.5 0.2 0.4 0.9 1.1 1.1 0.0 1.2 0.4 0.4 0.5 0.0 0.6 0.9 0.0 0.0 2.2 0.0 0.6 0.7 0.0 0.0 0.4 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.6 1.1 1.8 0.0 0.1 2.3 0.0 1.5 0.8 0.1 0.3 0.4 1.3 0.5 1.4 0.4 1.0 0.8 LY6G6D "C6orf23, G6D, Ly6-D, MEGT1, NG25" ENSG00000244355 "Lymphocyte antigen 6 family member G6D" O95868 6 31715356-31717804 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skin 1: 24.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 22 "colorectal cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HEL: 1.7" "Region enhanced" "Detected in many" "cerebellum: 6.1" HPA054412 Uncertain "Intracellular and membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 36: HEL - Hemostasis" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA054412: AB_2682480" "unprognostic (5.48e-2)" "unprognostic (1.25e-1)" "unprognostic (2.81e-2)" "unprognostic (2.13e-1)" 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 3.9 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.1 0.0 0.0 1.4 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 LY6G6E "C6orf22, G6e" ENSG00000255552 "Lymphocyte antigen 6 family member G6E" 6 31711771-31714065 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.4;skin 1: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 114 "HEL: 23.7" HPA056234 Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" Nucleoplasm "HPA056234: AB_2732601" "unprognostic (1.77e-1)" "unprognostic (1.58e-2)" "unprognostic (2.25e-1)" "unprognostic (6.88e-2)" 0.1 0.0 0.2 0.0 0.2 1.4 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.4 0.1 0.1 0.2 0.1 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LY6H NMLY6 ENSG00000176956 "Lymphocyte antigen 6 family member H" O94772 8 143157914-143160711 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 114.7;choroid plexus: 35.0;pituitary gland: 55.5" "Cell type enhanced" "Detected in some" "Adipocytes: 20.0;Endothelial cells: 18.7;Enteroendocrine cells: 54.9;Excitatory neurons: 24.8;Inhibitory neurons: 47.8;Ionocytes: 22.4;Oligodendrocyte precursor cells: 22.6;Spermatogonia: 22.4" "Cancer enhanced" "Detected in many" "glioma: 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "MOLT-4: 2.9;SCLC-21H: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077218 Enhanced "Intracellular and membrane" NA NA 12000 "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA077218: " "unprognostic (8.76e-2)" "unprognostic (2.76e-1)" "unprognostic (1.41e-2)" "unprognostic (9.45e-4)" "unprognostic (3.34e-3)" "unprognostic (1.82e-1)" "unprognostic (1.71e-4)" "unprognostic (2.26e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-3)" "unprognostic (3.76e-3)" "unprognostic (5.97e-2)" "unprognostic (2.20e-5)" "unprognostic (6.43e-3)" "unprognostic (1.54e-1)" "unprognostic (8.98e-2)" "unprognostic (9.89e-3)" 2.2 0.4 78.5 0.2 90.6 0.0 0.8 35.7 114.7 1.5 35.0 24.0 2.5 1.6 0.0 1.3 2.0 0.0 0.3 97.9 111.5 0.6 0.1 1.4 0.1 43.4 56.3 1.0 1.0 0.0 55.5 0.0 48.7 0.9 0.0 0.5 0.1 0.0 0.2 0.4 6.6 0.4 46.2 0.2 11.8 5.8 92.6 0.0 0.9 0.0 0.0 0.6 0.4 54.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 78.5 90.6 35.7 114.7 97.9 111.5 43.4 56.3 48.7 46.2 92.6 54.3 20.0 0.0 0.0 9.1 0.0 0.6 0.2 0.3 0.0 5.8 0.6 0.0 6.2 0.0 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.5 0.8 0.1 18.7 54.9 0.0 24.8 0.0 0.1 3.7 12.2 0.0 0.0 2.7 0.0 0.0 0.1 0.0 47.8 0.9 22.4 0.0 0.0 2.2 0.0 0.1 0.0 13.1 0.0 2.3 0.0 22.6 5.9 0.1 0.0 0.0 0.0 1.4 0.0 0.0 2.2 3.5 0.0 0.1 0.4 1.9 22.4 0.3 0.0 0.0 0.0 2.5 0.2 0.5 LY6K "CT97, FLJ35226, HSJ001348" ENSG00000160886 "Lymphocyte antigen 6 family member K" Q17RY6 8 142700111-142705127 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.5;testis: 36.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 186.7;Prostatic glandular cells: 105.2;Spermatocytes: 404.4;Spermatogonia: 105.8;Urothelial cells: 131.4" "Cancer enhanced" "Detected in many" "cervical cancer: 11.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.8" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.8" "Cell line enhanced" "Detected in many" "A-431: 125.2;BJ: 131.9;HeLa: 142.4;SiHa: 206.3;U-2197: 273.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017770, CAB075742, CAB075743, CAB079929" Enhanced Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 18: U-2197 - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB075742: AB_2665748, CAB075743: AB_2665749, CAB079929: , HPA017770: AB_1853414" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (1.48e-1)" "unprognostic (7.23e-3)" "unprognostic (3.47e-2)" "unprognostic (2.39e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.17e-5)" "unprognostic (4.18e-2)" "unprognostic (6.89e-2)" "unprognostic (9.75e-2)" "unprognostic (1.40e-1)" "unprognostic (5.27e-5)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.61e-2)" 5.4 0.2 0.6 0.2 0.6 0.3 4.4 0.9 1.7 3.3 0.0 0.5 0.3 0.5 0.2 12.5 1.2 0.4 1.5 0.8 1.0 3.0 0.2 0.8 0.2 1.7 0.8 0.7 0.3 0.0 0.4 2.4 2.0 1.1 0.0 2.4 1.7 0.8 5.4 6.8 0.3 0.1 1.1 0.2 1.1 36.0 0.7 0.6 1.0 1.3 0.6 1.0 5.1 1.1 125.2 2.0 0.0 6.3 2.4 7.9 1.5 131.9 15.3 39.9 24.0 0.2 0.5 0.0 10.9 15.0 14.3 10.8 0.0 7.5 33.5 1.2 0.2 0.1 142.4 0.3 1.9 0.0 0.0 11.7 21.1 29.7 38.0 0.1 3.7 0.0 0.0 0.6 76.2 1.0 0.2 0.3 4.2 4.1 2.0 0.3 0.5 0.2 6.7 1.7 3.7 0.5 206.3 2.7 41.3 6.6 0.5 0.2 5.4 1.9 11.8 273.2 0.2 0.2 0.1 0.3 0.6 0.1 13.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.6 0.6 0.9 1.7 0.8 1.0 1.7 0.8 2.0 1.1 0.7 1.1 25.6 3.2 0.5 0.0 0.4 38.9 54.2 4.3 21.6 0.6 15.1 49.8 0.2 5.7 9.8 25.8 0.0 13.5 0.3 0.0 0.0 0.8 7.7 3.1 8.5 9.2 0.0 0.0 0.0 0.0 186.7 8.0 0.0 9.0 0.0 0.0 3.3 0.1 6.0 0.0 0.0 0.0 6.1 0.3 28.7 14.8 4.1 4.6 12.4 0.0 0.0 0.5 0.0 0.0 0.1 6.7 1.1 3.0 0.0 105.2 0.0 0.2 3.6 0.6 0.0 17.8 13.1 404.4 105.8 32.2 44.9 25.3 0.7 0.1 0.0 131.4 LY6L ENSG00000261667 "Lymphocyte antigen 6 family member L" H3BQJ8 8 143080457-143083001 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.1;kidney: 1.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "prostate cancer: 2.8" "Region enhanced" "Detected in single" "thalamus: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 7: Kidney - Transmembrane transport" "unprognostic (5.25e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 9 "B-cells: 124.9;Hofbauer cells: 191.7;Kupffer cells: 199.1;Langerhans cells: 118.6;Macrophages: 149.8;Microglial cells: 105.9;monocytes: 155.6" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Cell line enhanced" "Detected in some" "Daudi: 69.5;NB-4: 44.7;RPMI-8226: 245.0;THP-1: 103.8;U-937: 45.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" 9.7 10.3 14.0 30.9 13.5 29.2 7.4 14.7 22.0 8.2 14.2 7.6 4.9 3.8 2.8 3.1 4.3 14.6 2.9 13.5 15.8 3.1 13.3 29.7 72.1 17.8 15.4 3.3 3.0 3.4 2.3 14.5 18.7 3.8 11.1 1.2 5.5 6.2 0.7 3.4 16.8 11.1 17.8 52.7 6.2 1.8 18.0 15.1 1.5 1.1 78.4 15.6 1.1 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 44.7 0.0 0.0 0.0 8.0 0.0 245.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 103.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 30.3 0.0 45.8 0.0 4.1 426.6 3.5 1.0 234.9 0.7 335.1 1.1 1.1 426.1 248.8 4.7 2.7 9.1 5.3 88.3 16.3 1.8 221.1 14.0 13.5 14.7 22.0 13.5 15.8 17.8 15.4 18.7 17.8 18.0 24.8 1.2 0.0 15.0 1.6 124.9 2.0 0.0 0.0 0.0 0.0 0.9 3.7 1.5 1.5 1.3 0.0 0.0 1.4 9.8 0.0 0.0 0.0 3.4 0.4 0.1 5.4 0.0 3.8 3.8 0.0 1.8 2.1 0.0 0.0 1.3 0.0 4.2 1.3 191.7 0.0 0.6 0.3 0.0 199.1 118.6 15.4 0.3 149.8 0.0 105.9 155.6 0.0 4.1 0.5 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.7 0.4 6.6 0.4 0.2 5.3 0.2 0.3 2.4 1.9 3.6 0.0 0.2 0.2 LY9 "CD229, hly9, mLY9, SLAMF3" ENSG00000122224 "Lymphocyte antigen 9" Q9HBG7 1 160796074-160828261 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.5;intestine: 12.0;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in some" "B-cells: 244.0;dendritic cells: 36.2;Melanocytes: 71.2;Plasma cells: 102.5;T-cells: 44.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 112.9;MAIT T-cell: 113.5;memory B-cell: 56.1;memory CD4 T-cell: 97.6;memory CD8 T-cell: 109.8;naive B-cell: 52.8;naive CD4 T-cell: 109.6;naive CD8 T-cell: 112.3;plasmacytoid DC: 72.8;T-reg: 80.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 14.3;JURKAT: 14.1;Karpas-707: 28.0;U-266/70: 70.7;U-266/84: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050917 Approved Approved "Plasma membrane,Centriolar satellite" NA NA 43000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Centriolar satellite" "HPA050917: AB_2681272" "unprognostic (8.04e-4)" "unprognostic (2.31e-5)" "unprognostic (8.08e-3)" "unprognostic (1.20e-3)" "unprognostic (9.83e-3)" "unprognostic (1.87e-5)" "unprognostic (1.16e-2)" "unprognostic (3.84e-3)" "unprognostic (1.23e-2)" "unprognostic (2.89e-3)" "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.69e-2)" "unprognostic (9.47e-2)" "unprognostic (3.49e-2)" "unprognostic (6.88e-2)" 2.4 0.9 0.1 13.7 0.2 11.5 2.0 0.1 0.2 0.8 0.2 3.9 4.0 0.6 0.4 0.9 0.9 2.5 0.5 0.1 0.2 1.1 2.3 3.8 30.2 0.3 0.2 0.6 0.2 0.0 0.2 0.3 0.2 1.1 3.8 0.0 7.1 0.4 0.3 0.8 12.0 0.5 0.3 26.7 6.0 0.2 0.2 25.5 1.4 0.2 31.1 3.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 28.0 0.0 0.0 2.3 0.5 0.1 0.8 0.0 1.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 70.7 29.3 0.3 0.0 4.0 0.0 1.2 0.8 0.4 112.9 1.1 113.5 56.1 97.6 109.8 5.2 52.8 109.6 112.3 2.4 22.2 0.8 72.8 80.3 53.5 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.2 0.2 0.3 0.2 0.2 0.4 0.0 1.8 0.3 244.0 1.0 0.5 0.1 0.0 0.0 0.4 0.8 0.9 0.0 0.0 0.0 0.0 0.1 36.2 0.1 0.0 0.0 0.1 0.1 0.1 0.7 1.2 28.0 0.1 0.2 0.0 1.4 0.5 0.1 0.0 0.0 1.8 0.4 1.9 0.0 0.1 0.0 0.0 3.2 31.9 0.0 0.0 6.3 71.2 1.9 2.1 0.0 22.6 0.0 0.1 0.1 0.0 0.0 102.5 0.2 0.0 0.3 0.0 0.0 0.0 0.5 0.6 0.0 0.1 0.5 1.0 0.1 44.8 0.0 0.3 0.3 LY96 MD-2 ENSG00000154589 "Lymphocyte antigen 96" Q9Y6Y9 8 73991392-74029079 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 570.8;Kupffer cells: 544.6;Langerhans cells: 155.4;Macrophages: 198.5;monocytes: 136.0;Plasma cells: 172.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 627.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 627.0" "Cell line enhanced" "Detected in many" "GAMG: 75.1;Karpas-707: 184.9;RPMI-8226: 94.0;U-87 MG: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053060 Approved Vesicles "Secreted to blood" NA NA 250000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA053060: AB_2682029" "unprognostic (2.96e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-1)" "unprognostic (1.85e-1)" "unprognostic (1.64e-2)" "unprognostic (2.87e-1)" "unprognostic (2.12e-3)" "unprognostic (1.42e-1)" "unprognostic (8.29e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.38e-11)" "unprognostic (2.87e-2)" "unprognostic (1.29e-2)" "unprognostic (1.60e-2)" "unprognostic (5.90e-2)" 28.6 12.4 12.9 42.4 13.5 17.9 24.7 13.1 22.7 12.9 13.8 15.7 12.3 10.5 5.4 9.0 11.1 35.3 9.5 13.0 14.4 13.2 22.8 22.0 47.4 16.3 14.8 22.6 3.7 2.4 8.0 44.9 14.9 6.1 14.5 1.2 11.4 6.7 3.8 4.4 9.9 20.3 14.7 59.6 10.6 4.7 13.9 16.2 7.3 9.8 39.3 30.5 7.9 17.1 1.5 0.0 0.3 0.2 34.5 73.2 0.1 49.5 61.9 13.5 31.1 0.0 0.5 15.9 16.7 32.6 75.1 0.5 0.2 0.6 34.4 17.1 0.3 0.3 0.0 1.8 17.5 2.7 0.9 21.2 0.4 21.9 4.3 2.2 67.2 9.7 0.2 184.9 48.9 0.0 6.5 2.1 0.2 0.0 1.0 6.4 0.0 94.0 2.5 0.0 0.3 0.2 0.0 0.2 6.5 0.3 0.0 3.3 52.1 33.5 2.6 18.0 12.1 48.1 24.7 9.6 92.3 1.0 14.7 13.7 90.2 0.4 0.5 85.1 1.3 26.3 12.8 1.9 45.8 15.1 8.2 2.9 627.0 0.2 71.8 37.6 21.6 30.6 12.9 13.5 13.1 22.7 13.0 14.4 16.3 14.8 14.9 14.7 13.9 17.1 35.1 16.0 10.7 0.0 48.4 13.8 1.2 1.3 0.0 0.2 11.2 4.4 2.4 0.0 9.7 3.7 0.0 2.7 16.3 0.1 0.0 6.8 24.2 0.3 1.0 63.6 0.0 14.1 2.8 7.4 3.1 32.9 0.0 0.3 3.8 0.0 104.2 3.3 570.8 0.0 3.9 0.0 2.0 544.6 155.4 3.1 14.3 198.5 76.5 21.5 136.0 0.0 1.0 0.5 1.1 9.4 0.0 6.8 172.6 0.8 0.0 1.1 5.6 0.2 6.6 20.0 14.0 0.7 0.2 2.2 11.6 6.4 21.8 12.4 0.3 1.4 LYG1 SALW1939 ENSG00000144214 "Lysozyme g1" Q8N1E2 2 99284238-99304742 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.5" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 161.4" "Cancer enriched" "Detected in many" 15 "renal cancer: 31.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.53e-2)" "unprognostic (3.13e-2)" "unprognostic (1.53e-2)" "unprognostic (3.73e-1)" "unprognostic (9.74e-2)" "unprognostic (3.76e-4)" "unprognostic (6.94e-4)" "unprognostic (2.58e-2)" "unprognostic (4.72e-2)" "unprognostic (9.74e-3)" "unprognostic (5.01e-2)" "unprognostic (1.06e-2)" "prognostic favorable (8.44e-4)" "unprognostic (1.31e-1)" "unprognostic (2.58e-1)" "unprognostic (1.07e-1)" "unprognostic (2.31e-3)" 1.9 1.6 3.1 1.2 3.3 0.9 2.1 6.0 4.3 3.6 1.8 2.3 1.2 2.3 1.8 1.3 2.3 0.8 2.0 3.0 2.6 23.5 5.8 1.9 1.6 3.2 2.8 2.4 1.6 0.2 2.0 0.7 3.2 3.3 1.1 2.6 1.7 0.7 2.1 1.7 2.8 0.9 2.6 4.7 1.7 5.5 3.1 2.4 2.6 0.4 1.3 2.5 2.3 4.1 0.3 2.3 1.7 2.8 3.9 2.2 1.9 0.9 1.0 0.9 1.5 0.4 2.0 0.5 1.5 0.4 0.2 1.0 2.3 0.3 1.1 1.6 1.4 1.3 2.0 0.7 0.7 0.4 3.1 1.8 2.4 1.4 0.6 2.0 0.5 3.0 0.7 1.5 1.0 0.5 1.2 4.0 0.4 1.2 2.1 2.9 1.0 0.8 3.9 0.9 1.0 0.6 0.3 0.7 0.6 2.0 0.3 0.4 1.3 1.2 1.4 2.0 1.0 1.7 1.0 0.3 0.3 2.4 0.5 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.1 3.1 3.3 6.0 4.3 3.0 2.6 3.2 2.8 3.2 2.6 3.1 4.1 0.6 0.0 0.0 3.6 1.5 0.0 0.2 0.6 0.0 1.0 0.8 0.8 0.5 1.5 1.5 1.8 2.1 0.3 0.5 0.5 21.5 0.7 10.8 0.2 0.3 0.5 0.0 0.0 4.6 0.2 0.2 0.4 0.0 0.2 4.5 0.8 1.1 0.5 0.3 0.0 4.2 0.3 0.0 0.3 0.3 4.8 0.3 1.4 0.0 2.8 0.8 0.2 0.0 2.0 5.6 0.6 0.1 0.4 0.0 0.6 0.2 161.4 0.2 0.6 0.0 0.1 0.5 2.4 1.1 0.0 0.0 0.5 0.6 0.3 0.4 0.2 LYG2 LYGH ENSG00000185674 "Lysozyme g2" Q86SG7 2 99242246-99255282 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.8;retina: 3.5;skin 1: 8.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 13.7;Cone photoreceptor cells: 14.6;Excitatory neurons: 19.6;Horizontal cells: 15.2;Inhibitory neurons: 17.5;Rod photoreceptor cells: 29.9" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.9" "Region enriched" "Detected in some" 4 "cerebellum: 4.8" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "THP-1: 1.7;U-937: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039179 Uncertain "Secreted in other tissues" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA039179: AB_10794633" "unprognostic (5.12e-2)" "unprognostic (8.70e-3)" "unprognostic (6.29e-2)" "unprognostic (3.91e-2)" "unprognostic (1.47e-1)" "unprognostic (7.29e-2)" "unprognostic (1.86e-2)" "unprognostic (1.78e-2)" "unprognostic (1.90e-1)" "unprognostic (1.30e-2)" "unprognostic (1.30e-5)" "unprognostic (1.40e-3)" "unprognostic (1.08e-13)" "unprognostic (9.98e-2)" "unprognostic (1.44e-1)" "unprognostic (1.19e-2)" "unprognostic (9.24e-3)" 0.2 0.1 0.4 0.1 0.5 0.5 0.0 4.8 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 3.5 0.3 0.0 0.3 8.8 0.1 0.0 0.0 0.2 0.2 1.4 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 0.4 0.4 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.3 0.9 0.2 0.0 1.0 0.2 0.0 0.0 0.1 0.4 0.1 0.2 0.6 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 1.0 0.2 0.6 0.3 0.0 1.2 0.2 0.6 0.4 1.1 0.3 0.5 0.1 0.0 0.0 0.0 0.4 0.3 1.7 0.6 0.6 0.4 0.1 0.4 0.2 0.8 0.1 0.3 2.5 0.4 0.0 0.2 0.1 0.3 0.0 0.2 0.6 0.8 0.4 0.0 1.1 0.3 0.3 0.1 0.2 0.0 0.9 0.1 0.0 0.4 0.5 4.8 1.0 0.6 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.9 0.0 0.0 5.5 1.2 0.6 0.5 0.3 0.0 13.7 0.8 0.9 0.3 5.7 0.1 0.0 14.6 0.9 1.6 0.1 0.0 0.1 6.1 0.6 0.9 0.7 0.0 0.0 19.6 0.0 0.2 0.8 0.0 0.3 0.0 0.5 1.1 0.0 0.2 15.2 17.5 0.0 0.0 0.9 0.3 2.2 0.0 0.2 1.8 0.0 0.2 6.9 4.1 7.5 8.9 0.1 0.0 0.7 0.0 0.7 0.3 0.3 0.0 29.9 0.0 2.0 0.9 1.8 1.6 0.0 0.4 0.3 0.9 0.2 0.4 0.1 LYL1 bHLHa18 ENSG00000104903 "LYL1 basic helix-loop-helix family member" P12980 19 13099033-13103161 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.9;lymphoid tissue: 36.7" "Cell type enhanced" "Detected in many" "Early spermatids: 335.4;Erythroid cells: 298.9;Late spermatids: 763.9;Spermatocytes: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.4" "Group enriched" "Detected in many" 4 "B-cells: 3.7;granulocytes: 6.4;monocytes: 2.8" "Cell line enhanced" "Detected in many" "HEL: 127.7;HL-60: 90.5;HMC-1: 206.6;K-562: 102.1;NB-4: 131.9;REH: 96.5;THP-1: 86.1;U-937: 86.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA072177 Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "HPA072177: " "unprognostic (8.62e-2)" "unprognostic (1.58e-1)" "unprognostic (1.27e-2)" "unprognostic (3.29e-3)" "unprognostic (2.76e-1)" "unprognostic (3.64e-3)" "unprognostic (2.46e-1)" "unprognostic (1.05e-2)" "unprognostic (1.90e-2)" "unprognostic (5.87e-2)" "unprognostic (1.78e-3)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.89e-4)" "unprognostic (1.18e-1)" "unprognostic (6.54e-2)" "unprognostic (1.33e-1)" "unprognostic (4.28e-1)" 9.7 4.1 6.3 10.9 6.0 35.9 7.3 7.1 7.5 6.7 4.9 6.4 2.0 7.7 0.3 3.2 5.8 1.4 10.1 6.4 6.4 5.7 2.6 12.3 12.3 8.9 6.8 2.8 2.0 0.5 2.5 5.6 8.1 5.7 0.6 0.0 3.7 1.3 2.8 3.2 14.1 1.8 9.1 36.7 4.1 20.8 9.0 2.3 5.3 1.9 6.2 7.8 5.6 9.6 0.1 0.3 0.2 0.0 0.0 0.3 0.0 1.4 0.2 0.4 0.1 0.5 0.0 24.8 8.4 0.2 0.0 0.1 0.4 0.0 0.0 14.7 0.0 127.7 0.1 1.2 1.4 90.5 206.6 0.4 0.0 0.1 0.0 0.0 31.9 0.0 102.1 4.4 0.0 0.0 0.5 131.9 0.0 0.4 3.2 96.5 0.3 11.2 0.0 0.0 0.1 9.1 2.8 0.0 6.0 0.0 0.0 86.1 51.8 0.0 0.1 3.6 0.1 0.0 0.0 20.3 0.1 86.1 0.1 2.4 1.4 6.4 0.0 1.9 0.1 2.1 0.2 0.1 1.0 3.7 0.1 0.1 2.4 0.0 2.8 0.3 0.4 0.4 6.3 6.0 7.1 7.5 6.4 6.4 8.9 6.8 8.1 9.1 9.0 9.6 33.7 0.0 0.5 0.0 80.1 2.5 0.5 0.1 0.6 0.0 1.0 1.4 2.3 2.8 0.2 1.8 0.0 0.7 6.6 1.6 0.0 0.4 335.4 0.4 1.9 40.1 1.8 298.9 0.4 0.0 1.3 3.2 1.1 0.2 45.1 0.8 32.9 1.1 113.2 0.0 0.3 1.2 0.0 60.3 35.1 763.9 8.1 68.3 7.2 13.1 36.4 1.5 4.1 0.5 1.3 2.0 1.6 12.0 6.3 0.4 1.7 0.5 1.7 0.2 13.1 1.8 2.2 120.6 5.8 1.4 1.8 1.5 9.0 0.5 1.0 0.6 LYNX1 SLURP2 ENSG00000180155 "Ly6/neurotoxin 1" P0DP58 8 142771197-142777810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 136.8;heart muscle: 79.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 34.8;Cardiomyocytes: 76.0;Club cells: 110.5;Excitatory neurons: 35.3;Hepatocytes: 34.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 12 "intermediate monocyte: 6.6;non-classical monocyte: 17.5" "Lineage enriched" "Detected in many" 17 "monocytes: 17.5" "Cell line enhanced" "Detected in many" "BJ: 7.9;fHDF/TERT166: 8.9;GAMG: 11.4;HHSteC: 8.3;HSkMC: 7.5;OE19: 7.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 51: Monocytes - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (8.67e-2)" "unprognostic (6.96e-2)" "unprognostic (1.31e-2)" "unprognostic (2.79e-3)" "unprognostic (1.04e-3)" "unprognostic (5.13e-3)" "unprognostic (1.33e-1)" "unprognostic (5.55e-3)" "unprognostic (1.12e-1)" "unprognostic (3.61e-3)" "unprognostic (7.21e-2)" "unprognostic (1.03e-2)" "prognostic favorable (2.82e-4)" "unprognostic (2.02e-2)" "unprognostic (2.28e-1)" "unprognostic (1.64e-2)" "unprognostic (1.85e-1)" 11.2 28.5 11.4 3.5 22.1 0.3 10.4 3.0 136.8 13.2 0.0 18.6 4.0 19.7 4.9 20.8 18.8 9.1 79.0 79.6 7.1 14.4 35.0 9.2 1.8 47.0 14.8 12.8 10.1 28.4 15.0 2.9 41.2 17.5 2.5 7.0 17.3 13.4 6.2 23.9 6.4 11.2 0.0 13.1 11.4 3.1 33.3 0.8 9.4 11.5 2.1 15.0 13.5 56.7 0.1 5.6 0.3 0.0 2.2 0.3 0.1 7.9 0.6 1.1 1.3 0.3 1.3 0.0 3.9 8.9 11.4 1.5 0.2 0.0 0.3 0.0 0.2 0.0 0.2 1.4 8.3 0.0 3.8 7.5 1.3 2.3 0.0 0.2 0.9 0.0 0.0 0.3 0.8 0.0 0.0 0.1 1.9 7.8 0.1 0.0 0.0 0.0 3.0 0.0 0.6 4.5 0.6 6.1 0.0 3.5 6.5 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.0 0.2 6.6 0.1 0.0 0.0 0.0 1.0 0.0 0.3 0.1 0.0 0.0 17.5 0.0 0.0 0.3 11.4 22.1 3.0 136.8 79.6 7.1 47.0 14.8 41.2 0.0 33.3 56.7 2.5 0.0 0.0 8.8 0.3 5.7 1.1 34.8 0.6 8.7 7.8 3.8 76.0 4.3 110.5 0.0 0.0 0.2 0.1 0.0 3.9 1.0 0.3 0.1 1.5 5.8 0.0 2.7 35.3 0.4 0.3 6.1 1.1 0.1 1.3 1.1 15.4 34.5 3.5 21.9 22.0 0.2 16.2 3.2 3.6 1.2 5.0 1.7 5.4 8.4 0.4 12.3 0.0 7.1 12.9 0.3 0.0 8.2 0.1 1.0 0.0 2.7 26.6 6.3 6.6 6.9 18.9 0.7 1.9 30.7 33.2 0.5 0.3 2.4 0.0 3.1 LYNX1-SLURP2 ENSG00000284505 "LYNX1-SLURP2 readthrough" 8 142764334-142778224 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 6.3;intestine: 7.0" "Cell type enriched" "Detected in single" 12 "Pancreatic endocrine cells: 10.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 8 "monocytes: 1.4" "Cell line enhanced" "Detected in single" "BJ: 1.0" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" 1.5 1.0 0.3 0.2 0.4 0.0 0.5 1.1 2.5 2.1 0.3 7.0 0.3 2.0 0.3 6.3 1.3 0.3 1.5 0.7 0.2 0.5 0.9 0.4 0.1 1.4 0.3 0.6 0.2 0.5 1.0 0.1 1.4 1.8 0.2 0.2 0.7 1.7 0.8 3.4 1.0 0.3 0.6 0.3 2.2 0.6 0.6 0.0 0.4 0.2 0.3 3.8 2.5 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.3 0.4 1.1 2.5 0.7 0.2 1.4 0.3 1.4 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYPD1 "LYPDC1, MGC29643" ENSG00000150551 "LY6/PLAUR domain containing 1" Q8N2G4 2 132643286-132671579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 31.2;choroid plexus: 15.4;fallopian tube: 53.5;pituitary gland: 33.7" "Cell type enhanced" "Detected in some" "Ductal cells: 73.8;Exocrine glandular cells: 74.5;monocytes: 62.0;Oligodendrocyte precursor cells: 28.1;Pancreatic endocrine cells: 43.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 57.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 22 "granulocytes: 3.6" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 41.6;HUVEC TERT2: 32.7;SK-MEL-30: 36.5;U-251 MG: 65.9;WM-115: 140.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068333 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Vesicles, Plasma membrane" "HPA068333: " "unprognostic (9.25e-2)" "unprognostic (7.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-2)" "unprognostic (1.15e-1)" "unprognostic (2.07e-2)" "unprognostic (6.40e-3)" "unprognostic (5.60e-2)" "unprognostic (8.36e-3)" "unprognostic (1.05e-2)" "unprognostic (6.70e-2)" "unprognostic (2.86e-2)" "unprognostic (1.51e-2)" "unprognostic (1.43e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" 0.6 0.8 24.8 0.3 27.1 0.4 0.8 19.5 25.5 0.3 15.4 8.1 0.1 0.9 0.1 1.5 53.5 1.2 0.8 24.2 29.2 5.9 1.0 1.0 0.6 29.9 30.0 1.3 5.1 0.3 33.7 0.0 27.7 0.7 0.2 1.6 5.5 0.1 0.3 0.3 1.6 0.6 27.3 0.3 0.9 0.7 31.2 2.2 0.9 0.1 1.0 0.8 0.6 21.5 0.4 8.6 11.6 0.2 0.0 0.0 0.0 1.9 1.5 6.3 1.4 0.6 1.1 0.0 18.3 5.1 3.0 7.2 0.0 0.0 2.9 0.1 1.8 0.0 4.0 0.0 0.0 0.0 0.2 0.0 0.1 41.6 0.0 1.7 32.7 0.0 0.0 0.1 0.0 0.8 0.0 0.0 11.1 0.2 3.3 0.0 0.0 0.0 15.1 0.2 1.1 2.3 1.8 0.2 36.5 26.8 0.1 0.3 1.5 0.7 17.4 5.9 65.9 0.1 0.0 0.1 10.0 0.0 140.5 0.6 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 27.1 19.5 25.5 24.2 29.2 29.9 30.0 27.7 27.3 31.2 21.5 0.7 0.0 0.0 8.1 0.2 0.1 0.1 0.4 0.0 1.6 2.0 0.9 0.2 2.8 0.2 5.5 0.0 0.0 0.0 0.5 1.9 73.8 5.6 1.4 0.1 0.2 1.8 0.0 0.8 74.5 0.0 2.2 0.0 0.9 0.0 0.1 0.4 0.0 0.1 15.2 4.7 0.0 0.0 0.8 0.7 9.3 4.1 0.1 0.0 0.0 62.0 1.4 0.0 28.1 4.4 43.4 0.0 0.0 0.0 0.1 0.1 4.8 0.3 0.8 0.0 0.2 3.9 2.6 2.1 0.3 0.0 0.0 0.1 0.0 0.1 0.1 LYPD2 "LYPDC2, RGTR430, UNQ430" ENSG00000197353 "LY6/PLAUR domain containing 2" Q6UXB3 8 142750150-142752532 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "esophagus: 347.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 97.0;Club cells: 378.7;Ionocytes: 71.2;Respiratory ciliated cells: 77.4" "Cancer enhanced" "Detected in many" "cervical cancer: 45.9;ovarian cancer: 46.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 13 "non-classical monocyte: 440.1" "Lineage enriched" "Detected in many" 22 "monocytes: 440.1" "Cell line enhanced" "Detected in some" "EFO-21: 10.2;HaCaT: 2.8;OE19: 1.9" "Low region specificity" "Detected in many" HPA028599 Uncertain "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA028599: AB_10603777" "prognostic favorable (2.00e-4)" "unprognostic (3.10e-2)" "prognostic favorable (2.63e-4)" "unprognostic (3.85e-3)" "unprognostic (3.75e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-2)" "unprognostic (3.11e-3)" "unprognostic (1.53e-1)" "unprognostic (2.41e-1)" "unprognostic (1.85e-1)" "unprognostic (1.12e-1)" "unprognostic (2.04e-1)" 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.4 15.0 0.0 0.0 0.0 0.0 0.0 347.8 0.3 0.2 2.9 0.0 0.0 0.1 1.3 1.5 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.2 0.0 0.1 0.0 0.0 27.0 0.0 0.1 28.8 0.1 0.0 0.0 0.2 23.2 0.0 0.1 2.5 0.0 0.0 26.3 0.0 48.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 33.7 0.4 2.0 0.1 0.2 20.1 0.0 0.2 0.1 0.0 0.0 440.1 1.6 0.1 10.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 97.0 0.0 0.0 0.1 0.0 0.0 0.0 378.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 5.7 0.4 0.4 0.0 0.0 0.0 71.2 1.3 0.0 0.1 0.0 25.3 0.0 0.0 11.2 0.0 2.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 77.4 0.0 0.0 0.0 22.3 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.0 0.2 LYPD4 MGC42718 ENSG00000273111 "LY6/PLAUR domain containing 4" Q6UWN0 19 41837074-41844697 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 313 "testis: 104.8" "Group enriched" "Detected in some" 66 "Early spermatids: 283.3;Late spermatids: 869.2;Spermatocytes: 265.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (4.07e-2)" "unprognostic (2.92e-1)" "unprognostic (3.21e-1)" "unprognostic (1.00e-1)" 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 104.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 283.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 869.2 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 265.9 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYPD6 MGC52057 ENSG00000187123 "LY6/PLAUR domain containing 6" Q86Y78 2 149329985-149474138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;placenta: 15.7" "Cell type enhanced" "Detected in many" "Astrocytes: 40.8;Early spermatids: 59.7;Inhibitory neurons: 65.9;Late spermatids: 230.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 37.6;fHDF/TERT166: 48.2;HBF TERT88: 25.0;LHCN-M2: 46.2;RT4: 39.9" "Low region specificity" "Detected in all" HPA042805 Enhanced Approved Cytosol "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA042805: AB_10794159" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (7.23e-3)" "unprognostic (1.64e-2)" "unprognostic (3.25e-1)" "unprognostic (6.49e-3)" "unprognostic (6.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.73e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.14e-3)" "unprognostic (6.75e-2)" "unprognostic (7.33e-4)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.72e-4)" 1.4 0.3 8.0 0.6 4.6 0.0 9.3 4.5 5.5 0.9 1.2 1.5 1.7 2.1 0.1 0.5 1.6 11.1 0.6 4.7 9.8 2.0 0.3 0.2 0.2 6.8 24.0 0.6 1.9 1.4 0.3 15.7 6.7 1.4 2.5 7.0 0.2 1.3 0.1 0.6 1.4 2.9 5.6 0.6 3.9 6.8 16.1 0.3 0.2 0.1 1.3 2.6 0.4 4.2 0.2 0.0 6.8 37.6 0.0 0.1 0.5 15.0 6.6 18.9 11.7 0.2 3.0 0.0 0.8 48.2 9.1 3.8 5.3 0.1 25.0 0.0 1.7 0.1 9.6 0.0 0.2 0.0 0.0 0.0 0.4 0.0 11.0 0.4 0.3 0.0 0.0 0.0 46.2 6.7 0.0 3.6 5.4 3.2 4.3 0.0 20.1 0.0 2.3 39.9 1.5 6.7 10.1 11.2 1.2 12.2 1.5 0.8 0.0 0.4 5.7 0.5 8.2 0.0 0.0 0.0 3.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 4.6 4.5 5.5 4.7 9.8 6.8 24.0 6.7 5.6 16.1 4.2 0.1 0.0 0.0 40.8 0.0 0.1 0.6 1.0 1.2 2.7 11.7 6.6 0.4 10.0 2.0 0.0 0.0 0.0 0.0 0.4 3.9 2.6 59.7 1.7 0.4 0.9 0.0 0.0 0.3 0.9 0.2 1.4 10.7 2.5 0.0 0.7 0.4 0.0 0.3 0.0 65.9 2.8 0.0 0.0 0.0 230.4 3.1 0.0 0.0 1.0 0.0 4.1 0.0 13.6 1.0 4.5 0.4 0.4 0.1 2.1 1.7 0.0 0.8 3.4 0.0 0.1 0.2 1.0 5.2 0.7 0.0 0.3 0.1 0.0 2.0 1.7 LYPD6B "CT116, LYPD7" ENSG00000150556 "LY6/PLAUR domain containing 6B" Q8NI32 2 149038107-149215262 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 95.5" "Cell type enhanced" "Detected in many" "Early spermatids: 245.7;Gastric mucus-secreting cells: 87.7;Inhibitory neurons: 77.8;Late spermatids: 118.5;Suprabasal keratinocytes: 69.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 13.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.8" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 64.8;LHCN-M2: 102.3;NB-4: 34.7;RT4: 54.7;SK-BR-3: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049239 Uncertain "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "HPA049239: AB_2680688" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (3.12e-3)" "unprognostic (1.64e-1)" "unprognostic (3.37e-1)" "unprognostic (2.01e-2)" "unprognostic (6.27e-2)" "unprognostic (3.64e-2)" "unprognostic (7.95e-3)" "unprognostic (2.59e-2)" "unprognostic (4.40e-2)" "unprognostic (1.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (1.32e-3)" 0.3 0.2 3.5 0.4 2.5 0.2 16.4 1.6 5.3 2.8 1.6 1.7 2.6 0.9 1.2 4.1 23.4 37.3 0.0 4.3 4.1 20.5 0.9 1.7 0.4 2.3 7.3 0.4 12.3 16.1 0.4 0.8 3.0 11.1 3.3 1.0 5.8 15.2 0.2 95.5 1.2 0.3 1.9 2.8 41.3 34.1 8.0 0.3 0.2 0.0 1.9 14.2 6.3 2.1 1.4 0.0 0.0 1.5 0.0 0.1 0.1 8.0 1.5 6.6 2.5 1.0 0.0 0.0 0.0 64.8 0.0 14.0 1.5 1.3 20.6 0.0 7.4 0.0 1.9 0.0 0.2 0.0 0.1 0.6 21.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 102.3 24.3 0.0 34.7 2.0 14.6 0.3 0.0 0.4 4.3 3.2 54.7 3.9 0.1 0.4 32.1 0.0 6.3 4.8 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.8 13.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.5 2.5 1.6 5.3 4.3 4.1 2.3 7.3 3.0 1.9 8.0 2.1 0.5 0.0 2.0 2.3 5.5 29.8 21.0 30.6 6.2 0.0 23.4 17.1 1.4 42.9 23.9 46.0 0.0 0.1 0.1 4.0 7.9 12.4 245.7 5.2 0.3 1.0 2.4 2.7 4.6 19.1 0.7 0.8 87.7 5.7 0.0 0.4 0.0 0.1 0.1 0.0 77.8 3.9 8.2 0.0 2.8 118.5 2.1 0.4 5.4 0.0 0.6 0.0 0.0 0.0 0.4 30.9 6.0 0.0 4.5 40.6 5.7 0.2 21.4 0.0 0.0 0.0 1.3 4.2 1.7 3.5 69.0 0.3 1.1 0.0 3.5 53.7 LYPD8 ENSG00000259823 "LY6/PLAUR domain containing 8" Q6UX82 1 248739415-248755759 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 215.9" "Group enriched" "Detected in some" 5 "Distal enterocytes: 710.5;Paneth cells: 1098.0" "Cancer enriched" "Detected in some" 7 "colorectal cancer: 15.2" "Group enriched" "Detected in many" 10 "amygdala: 1.1;basal ganglia: 1.6;cerebral cortex: 1.9;hippocampal formation: 1.1;white matter: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.69e-3)" "unprognostic (3.53e-2)" "unprognostic (1.08e-5)" "unprognostic (1.42e-2)" "unprognostic (1.35e-1)" "unprognostic (2.16e-4)" "unprognostic (8.62e-2)" "unprognostic (7.28e-2)" "unprognostic (3.22e-1)" "unprognostic (9.73e-2)" "unprognostic (1.87e-1)" "unprognostic (1.19e-4)" "unprognostic (2.57e-1)" "unprognostic (2.89e-1)" "unprognostic (1.07e-1)" 0.1 0.0 1.1 11.4 1.6 0.5 0.6 0.0 1.9 0.0 0.0 215.9 0.7 0.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 126.8 0.0 0.0 0.4 0.0 0.0 26.4 3.5 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 1.1 1.6 0.0 1.9 1.1 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 710.5 1.9 0.0 4.7 0.0 0.0 0.0 31.5 0.0 15.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 166.9 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 1098.0 0.0 0.0 0.1 38.3 2.3 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.3 0.3 0.0 16.6 0.0 LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10588.1;salivary gland: 21115.5;stomach 1: 8941.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3106.1;Kupffer cells: 2841.2;Langerhans cells: 4859.1;Macrophages: 4870.7;monocytes: 7063.0;Pancreatic endocrine cells: 3152.5" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25266.2;myeloid DC: 14438.7" "Group enriched" "Detected in all" 20 "dendritic cells: 14438.7;monocytes: 25266.2" "Cell line enriched" "Detected in many" 13 "OE19: 12130.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 1500000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" 95.8 27.8 3.5 802.1 4.0 10588.1 128.2 3.7 18.5 156.2 11.4 309.0 3605.0 65.7 4.2 106.3 33.9 1054.6 34.8 2.6 4.3 32.4 138.0 1355.2 739.7 8.0 7.3 20.4 63.1 13.8 7.2 91.3 12.2 40.2 273.8 4.4 21115.5 21.8 34.0 58.7 1322.2 123.9 5.4 621.0 8941.1 21.8 10.9 321.8 27.8 36.4 652.8 428.5 16.2 11.7 0.6 0.1 0.0 0.2 0.0 0.0 4.8 0.0 0.0 0.0 0.3 9.5 6.5 4.2 1.5 0.0 3.6 1.2 0.0 0.0 0.2 1.2 0.1 62.4 1.0 960.4 0.0 110.6 50.5 0.0 0.1 0.0 0.0 0.2 0.0 0.3 7.7 0.3 0.0 0.2 2.6 109.5 2.3 12130.8 0.2 1.6 1.4 16.7 0.3 0.5 0.8 3.6 0.5 0.1 0.5 0.7 0.0 489.0 0.6 0.0 2.6 2.3 0.9 2.6 1.1 1.2 0.1 518.5 0.0 443.4 25266.2 298.2 32.6 4798.4 52.3 100.5 20.1 22.7 14438.7 20.8 20.0 17.8 1007.7 108.1 880.1 301.2 31.1 25392.1 3.5 4.0 3.7 18.5 2.6 4.3 8.0 7.3 12.2 5.4 10.9 11.7 24.0 86.6 285.8 0.0 80.8 57.2 1.7 1.2 1.2 0.3 1205.7 32.3 0.2 734.9 51.1 27.6 0.0 5.6 39.6 32.1 0.0 55.1 1.9 2.6 1.9 25.1 12.5 264.6 0.2 547.3 9.4 26.8 3106.1 2.9 123.6 0.5 29.6 25.4 887.1 0.0 0.2 112.4 0.0 2841.2 4859.1 17.4 4.1 4870.7 53.4 0.0 7063.0 0.1 176.1 0.0 0.3 3152.5 600.5 2.2 9.0 2.7 41.8 6.6 33.8 1.0 39.5 7.4 9.9 0.7 3.9 1.5 38.2 8.5 50.6 0.3 111.4 38.3 LYZL1 "LYC2, MGC33408" ENSG00000120563 "Lysozyme like 1" Q6UWQ5 10 29289061-29318328 "Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 429 "testis: 51.0" "Group enriched" "Detected in some" 37 "Early spermatids: 600.3;Late spermatids: 201.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (1.88e-1)" "unprognostic (8.40e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 600.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 201.8 5.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.0 10.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYZL2 ENSG00000151033 "Lysozyme like 2" Q7Z4W2 10 30611779-30629762 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 712 "testis: 71.1" "Group enriched" "Detected in some" 43 "Early spermatids: 786.1;Late spermatids: 204.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SK-BR-3: 3.0" "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.83e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 786.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 204.1 7.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.3 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYZL4 "LYC4, MGC26768" ENSG00000157093 "Lysozyme like 4" Q96KX0 3 42397083-42410610 "Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "testis: 52.1" "Group enriched" "Detected in some" 46 "Early spermatids: 386.3;Late spermatids: 158.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "OE19: 3.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA038806 Approved "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA038806: AB_10674841" "unprognostic (4.03e-1)" "unprognostic (5.68e-1)" "unprognostic (1.06e-1)" 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 52.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 386.3 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 158.8 3.1 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.9 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYZL6 "LYC1, PRO1485, TKAL754" ENSG00000275722 "Lysozyme like 6" O75951 17 35934518-35943713 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 132 "testis: 47.9" "Cell type enriched" "Detected in some" 6 "Early spermatids: 387.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025734, HPA053073" Enhanced "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA025734: AB_1853444, HPA053073: AB_2682034" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 47.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 387.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.3 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 15.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 M6PR "CD-M6PR, CD-MPR" ENSG00000003056 "Mannose-6-phosphate receptor, cation dependent" P20645 12 8940361-8949761 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 242.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 859.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034464, HPA040445" Approved NA NA 100000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB034464: AB_2139108, HPA040445: AB_2676989" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.74e-2)" "unprognostic (1.54e-1)" "unprognostic (3.00e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (3.89e-4)" "unprognostic (1.76e-1)" "unprognostic (2.84e-1)" "unprognostic (5.82e-3)" "unprognostic (1.44e-2)" "unprognostic (6.82e-2)" "unprognostic (4.53e-3)" "unprognostic (3.79e-2)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (3.98e-1)" 76.6 64.8 79.5 113.9 83.3 104.1 81.5 80.7 95.5 61.5 79.2 78.4 61.1 73.7 63.1 63.3 70.4 74.0 82.0 83.5 85.9 79.1 78.9 97.5 138.8 85.7 83.8 62.8 59.6 95.0 34.0 78.6 86.2 64.9 91.8 73.7 79.2 74.5 51.9 60.4 64.5 81.1 84.0 132.5 74.8 59.7 90.8 105.4 96.4 56.0 125.4 98.0 37.5 96.4 103.6 159.7 103.0 122.0 187.7 86.8 306.2 129.7 159.4 186.2 210.7 176.4 268.4 188.9 48.9 133.0 374.4 160.0 142.7 131.2 218.8 859.9 86.6 331.3 125.0 122.4 213.7 355.6 566.6 126.0 166.3 184.4 232.5 179.2 105.5 123.3 93.0 114.6 165.2 103.7 120.7 142.3 412.8 189.0 72.4 118.0 248.0 108.4 151.9 241.2 26.5 109.9 159.8 159.4 223.9 363.8 39.0 251.3 106.0 156.3 175.1 186.6 193.2 139.3 253.5 201.4 183.2 226.4 120.5 706.9 292.0 319.1 177.4 477.6 201.5 123.2 210.7 195.5 334.0 111.4 152.7 170.6 44.5 186.3 567.4 205.0 182.3 497.3 79.5 83.3 80.7 95.5 83.5 85.9 85.7 83.8 86.2 84.0 90.8 96.4 49.9 57.7 57.0 13.4 75.2 44.1 73.0 73.1 43.9 46.1 50.1 40.8 10.7 44.3 68.0 31.3 22.9 64.4 107.0 23.4 19.6 91.8 7.9 31.3 36.7 39.6 38.3 60.1 25.9 66.9 71.4 37.2 30.5 33.7 132.3 39.9 37.1 28.3 242.8 55.5 29.0 30.5 40.7 138.9 95.4 7.9 35.1 166.4 67.6 21.5 212.2 35.8 159.6 17.1 22.7 56.1 29.5 32.0 73.7 65.4 25.7 41.8 53.1 37.4 26.3 52.5 43.7 117.5 54.4 51.6 40.5 53.1 96.4 55.8 43.8 68.2 MAD1L1 "HsMAD1, MAD1, PIG9, TP53I9, TXBP181" ENSG00000002822 "Mitotic arrest deficient 1 like 1" Q9Y6D9 7 1815793-2233243 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 316.9;Late spermatids: 685.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003635, CAB015338" Supported Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "CAB015338: AB_627901, HPA003635: AB_1853472" "unprognostic (1.85e-1)" "unprognostic (3.76e-2)" "unprognostic (4.26e-3)" "unprognostic (8.32e-2)" "unprognostic (1.42e-2)" "unprognostic (3.83e-2)" "unprognostic (2.70e-2)" "unprognostic (1.18e-2)" "unprognostic (4.78e-2)" "unprognostic (5.76e-2)" "unprognostic (1.89e-1)" "unprognostic (2.48e-1)" "unprognostic (2.33e-3)" "unprognostic (5.18e-2)" "unprognostic (1.33e-1)" "unprognostic (2.36e-1)" "unprognostic (4.57e-1)" 9.4 6.0 6.2 11.1 8.3 14.9 9.0 4.6 8.4 11.4 5.1 7.7 6.0 9.3 2.5 9.2 7.4 4.8 8.8 5.6 6.7 6.5 6.4 10.2 17.8 7.8 6.6 7.4 5.6 4.1 7.1 5.0 7.6 8.2 3.4 4.0 7.3 5.6 13.6 14.5 9.7 5.3 5.5 18.2 6.6 10.7 7.0 15.3 8.6 5.0 10.7 8.3 10.1 9.4 37.2 15.5 16.5 30.1 11.1 11.2 26.5 25.6 13.0 26.0 20.7 28.5 21.5 23.4 10.4 14.7 39.9 28.5 12.4 18.3 15.7 11.1 17.8 30.1 19.4 45.0 15.7 21.1 55.1 13.9 13.3 28.8 14.0 6.3 14.9 13.7 30.3 17.4 10.3 45.4 8.7 61.0 30.7 5.8 20.5 38.5 16.7 17.5 12.7 18.7 10.7 33.4 20.0 24.9 65.2 11.2 17.1 48.9 17.6 21.8 60.0 62.3 26.0 30.3 31.4 27.3 18.1 60.6 80.3 60.4 36.2 25.4 71.3 62.4 66.6 54.6 69.2 72.3 63.4 63.0 92.0 66.0 8.6 22.7 60.1 26.0 131.5 53.6 6.2 8.3 4.6 8.4 5.6 6.7 7.8 6.6 7.6 5.5 7.0 9.4 9.3 3.2 10.4 12.1 33.8 17.6 13.9 14.0 15.4 8.3 6.2 6.5 7.4 14.3 11.9 7.3 10.4 16.2 35.7 12.4 15.6 12.3 316.9 5.5 6.7 10.7 32.4 19.1 20.9 11.4 16.3 11.4 11.7 6.9 41.8 15.5 6.4 36.4 39.6 23.5 24.4 9.4 16.2 31.4 84.1 685.9 12.5 28.2 37.4 21.5 25.7 24.3 47.4 16.1 32.4 16.5 7.9 10.5 14.9 9.4 5.4 15.2 6.6 13.9 19.7 11.2 10.2 60.3 33.8 9.3 21.5 24.5 43.1 17.5 8.8 9.7 MAG "GMA, S-MAG, SIGLEC-4A, SIGLEC4A" ENSG00000105695 "Myelin associated glycoprotein" P20916 19 35292125-35313807 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "brain: 731.4" "Cell type enriched" "Detected in some" 12 "Oligodendrocytes: 267.8" "Cancer enriched" "Detected in some" 7 "glioma: 20.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.9" "Cell line enriched" "Detected in some" 22 "WM-115: 36.6" "Region enhanced" "Detected in all" "white matter: 2742.2" "Low region specificity" "Detected in all" "CAB009345, HPA012499" Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB009345: AB_670104, HPA012499: AB_1854238" "unprognostic (2.70e-3)" "unprognostic (2.70e-2)" "unprognostic (8.06e-3)" "unprognostic (1.23e-1)" "unprognostic (6.93e-2)" "unprognostic (3.74e-1)" "unprognostic (1.50e-1)" "unprognostic (2.39e-1)" "unprognostic (1.06e-1)" "unprognostic (2.00e-1)" "unprognostic (5.62e-2)" "unprognostic (5.18e-4)" "unprognostic (6.29e-2)" "unprognostic (2.19e-1)" "unprognostic (8.87e-2)" "unprognostic (1.66e-1)" 0.3 1.3 121.5 0.0 366.4 0.0 0.3 314.0 237.4 0.3 4.2 0.1 0.0 0.2 0.0 0.0 4.2 0.0 0.5 157.7 195.2 0.3 0.2 0.3 0.1 459.9 317.3 22.4 0.1 0.0 0.5 0.3 417.5 0.3 0.0 0.0 0.2 0.3 0.1 0.2 0.1 0.0 247.8 1.1 0.1 0.6 303.0 0.0 1.0 0.0 0.0 0.2 0.5 731.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 36.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 121.5 366.4 314.0 237.4 157.7 195.2 459.9 317.3 417.5 247.8 303.0 731.4 1.2 0.0 0.0 1.6 0.2 0.0 0.2 0.0 0.0 0.0 0.3 4.4 4.1 0.0 0.0 0.0 0.0 0.2 4.0 0.0 1.9 0.0 0.1 0.0 0.0 4.2 0.0 0.4 0.5 0.5 5.4 2.7 0.0 0.0 4.5 21.0 12.8 0.0 1.0 0.0 0.6 0.0 0.0 0.6 0.0 0.1 1.8 1.2 0.0 1.0 0.1 0.0 0.0 0.5 267.8 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 4.3 0.0 0.0 0.3 0.4 11.0 0.0 0.0 MAGT1 "DKFZp564K142, IAP, MRX95, OST3B, SLC58A1" ENSG00000102158 "Magnesium transporter 1" Q9H0U3 X 77825747-77895593 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 145.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049851 Approved "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA049851: AB_2680913" "prognostic unfavorable (1.30e-4)" "unprognostic (3.32e-1)" "unprognostic (6.47e-2)" "unprognostic (1.16e-1)" "unprognostic (2.39e-1)" "unprognostic (3.81e-3)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (8.98e-4)" "unprognostic (2.03e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.03e-1)" "unprognostic (1.60e-2)" "unprognostic (5.56e-3)" "unprognostic (1.14e-1)" "unprognostic (6.25e-3)" "unprognostic (1.66e-1)" 25.3 22.6 12.9 24.2 19.4 20.8 36.5 17.2 17.4 39.4 14.4 28.3 25.7 27.5 53.7 25.6 25.9 25.1 37.5 13.0 16.4 41.9 71.2 26.8 22.5 20.9 18.5 23.6 31.9 38.4 18.5 36.4 21.9 33.5 27.0 5.2 34.6 28.0 17.1 18.3 26.2 24.3 16.6 23.5 29.4 11.3 17.9 21.0 78.0 21.9 23.5 29.1 18.2 27.0 62.5 34.1 41.7 48.8 75.0 49.3 64.8 66.9 67.4 51.7 56.5 45.6 99.5 45.6 90.9 71.7 53.3 56.4 88.4 50.8 80.0 32.3 55.4 30.6 46.2 42.5 66.6 64.9 31.1 45.3 43.5 64.6 56.7 55.1 74.0 31.2 36.5 123.2 64.7 40.4 36.2 23.9 56.1 64.6 41.3 43.3 72.5 84.7 61.9 45.8 14.1 26.3 91.6 64.8 58.0 43.6 43.8 35.3 75.2 45.6 51.1 71.7 33.2 44.8 103.1 58.1 49.7 60.5 61.0 15.3 12.9 13.7 17.2 19.7 18.4 12.5 15.6 16.6 11.1 10.7 14.9 17.7 11.0 18.6 21.0 22.2 12.8 15.7 12.9 19.4 17.2 17.4 13.0 16.4 20.9 18.5 21.9 16.6 17.9 27.0 50.2 41.7 53.6 9.8 37.3 33.0 55.3 51.6 24.5 5.2 39.1 25.1 53.4 42.9 51.6 40.5 4.2 33.3 43.4 44.8 3.9 35.3 2.2 23.7 38.9 40.7 22.7 33.0 6.1 34.9 59.3 43.7 33.1 58.0 30.4 24.5 43.2 145.6 42.3 1.7 6.3 39.6 32.6 49.8 46.1 2.5 30.7 45.1 33.8 15.9 33.9 17.1 18.6 13.6 28.0 36.2 37.2 27.1 87.4 65.4 31.2 32.0 20.7 5.2 19.7 38.7 31.2 6.6 16.7 36.5 45.6 81.3 36.0 31.2 26.0 69.4 MALSU1 "C7orf30, mtRsfA" ENSG00000156928 "Mitochondrial assembly of ribosomal large subunit 1" Q96EH3 7 23298739-23311729 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "AN3-CA: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020487, HPA052210" Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA020487: AB_1845757, HPA052210: AB_2681762" "unprognostic (3.62e-1)" "unprognostic (3.68e-1)" "unprognostic (1.43e-1)" "unprognostic (4.66e-3)" "unprognostic (5.24e-3)" "prognostic unfavorable (9.71e-4)" "unprognostic (1.08e-1)" "unprognostic (1.51e-2)" "unprognostic (9.79e-2)" "unprognostic (1.83e-3)" "unprognostic (3.15e-2)" "unprognostic (7.15e-2)" "unprognostic (2.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.68e-1)" 2.6 3.2 2.8 1.6 2.9 2.0 2.2 3.3 3.7 1.9 3.7 2.7 1.0 1.8 2.3 3.9 2.3 1.4 5.1 2.7 2.7 3.1 5.6 2.0 2.9 2.5 2.5 2.6 2.9 2.3 2.0 3.4 2.5 1.6 1.7 1.8 1.9 2.3 6.3 1.8 1.8 1.8 2.4 1.8 2.2 4.9 2.9 1.5 3.3 6.4 1.9 2.1 1.9 3.0 9.2 11.4 8.8 47.8 7.8 5.4 7.6 6.1 5.0 6.2 5.7 19.7 8.1 8.8 7.0 4.4 27.5 8.7 7.9 4.3 7.6 4.2 12.9 5.2 15.0 30.4 5.0 12.2 3.2 4.6 6.5 5.3 5.8 41.5 5.8 8.5 16.5 2.3 7.9 6.4 8.4 37.2 15.1 18.0 29.0 6.5 6.7 12.4 6.1 8.1 7.0 8.5 5.0 8.9 16.1 17.2 4.5 7.3 9.8 5.2 4.0 10.0 12.5 2.6 8.6 14.7 20.6 15.0 17.3 0.7 1.0 0.7 0.8 0.8 1.0 1.0 1.2 1.0 1.0 1.0 1.4 0.9 0.7 0.9 0.7 0.9 1.2 1.0 2.8 2.9 3.3 3.7 2.7 2.7 2.5 2.5 2.5 2.4 2.9 3.0 40.5 38.5 41.7 12.7 32.1 43.7 54.8 58.3 30.1 29.1 38.6 60.8 97.1 37.1 40.0 44.1 16.7 77.6 25.7 22.3 115.4 90.6 168.5 50.2 31.9 38.9 19.2 35.3 14.7 96.3 68.7 44.9 16.3 31.7 14.5 41.5 44.3 106.8 54.0 18.5 16.6 32.5 50.8 26.3 15.1 33.6 49.4 22.3 35.6 8.4 44.5 46.8 30.9 18.6 20.2 73.2 28.2 49.2 34.9 61.2 38.1 117.6 44.6 35.8 32.9 35.6 65.6 82.2 75.2 42.4 44.2 49.8 25.2 61.7 44.4 49.2 MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671465-58754477 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoli fibrillar center" Cytosol "CAB004494: AB_627909, HPA048432: AB_2680389" "unprognostic (3.25e-1)" "unprognostic (2.31e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" "unprognostic (1.65e-3)" "unprognostic (4.67e-2)" "unprognostic (6.46e-2)" "unprognostic (4.50e-2)" "unprognostic (3.33e-2)" "unprognostic (4.16e-3)" "unprognostic (3.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.53e-2)" "unprognostic (2.34e-1)" "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" 7.1 2.5 2.9 11.2 2.8 10.5 6.3 4.8 3.6 7.7 4.2 5.1 3.6 5.4 4.2 12.5 5.1 5.8 5.4 3.1 4.1 6.7 6.9 7.3 21.1 3.2 2.6 5.3 4.0 5.3 4.7 4.0 3.0 11.5 5.5 8.7 5.8 3.8 8.3 9.4 7.7 4.2 3.0 11.5 4.6 8.2 4.1 15.6 5.3 2.8 23.1 7.1 9.6 3.6 11.4 16.0 16.8 5.2 3.1 6.7 9.2 19.7 12.1 15.7 12.6 13.8 13.5 27.0 10.3 24.0 11.1 12.0 10.8 7.6 20.8 17.0 6.8 9.7 9.0 21.8 4.0 20.1 11.4 4.0 12.2 11.8 10.4 6.6 3.4 7.7 15.3 42.3 9.6 3.3 4.7 9.7 6.3 4.1 7.1 14.8 11.5 19.7 88.9 2.8 2.5 4.5 11.7 6.0 9.3 12.0 5.1 12.2 5.7 22.6 9.1 7.1 20.8 38.5 54.4 16.3 10.6 15.6 9.9 0.3 0.5 0.2 0.7 0.7 0.6 1.1 1.4 0.8 0.7 2.1 1.0 0.8 0.3 0.5 0.5 1.3 0.8 0.4 2.9 2.8 4.8 3.6 3.1 4.1 3.2 2.6 3.0 3.0 4.1 3.6 35.0 22.4 19.2 24.2 67.8 33.0 32.3 4.8 26.2 14.7 13.6 11.0 14.4 10.0 7.0 11.0 85.5 6.2 53.2 11.1 3.9 16.6 12.7 10.4 17.5 31.1 6.7 0.8 61.3 8.5 6.0 15.7 13.7 24.7 31.7 28.1 10.4 11.1 11.8 55.5 42.9 8.6 8.2 21.0 96.5 8.0 10.2 55.9 12.4 34.7 79.5 26.2 20.6 52.3 11.9 16.2 21.9 7.2 42.2 46.6 8.0 30.7 5.8 18.1 19.7 16.1 12.9 40.1 35.6 25.4 24.7 9.0 55.2 5.7 10.7 38.1 MAMDC2 MGC21981 ENSG00000165072 "MAM domain containing 2" Q7Z304 9 70043848-70226972 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 74.5" "Cell type enhanced" "Detected in many" "Early spermatids: 42.5;Excitatory neurons: 37.0;Fibroblasts: 38.7;Inhibitory neurons: 42.9;Leydig cells: 96.6;Microglial cells: 45.9;Peritubular cells: 82.0;Sertoli cells: 39.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 55.7;HHSteC: 57.2;LHCN-M2: 75.0;TIME: 71.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021814, HPA022249" Uncertain Approved "Nuclear speckles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Plasma membrane" "HPA021814: AB_1853508, HPA022249: AB_2139157" "unprognostic (1.88e-1)" "unprognostic (3.16e-3)" "unprognostic (2.21e-3)" "unprognostic (2.71e-2)" "unprognostic (4.30e-2)" "unprognostic (8.49e-2)" "unprognostic (1.27e-2)" "unprognostic (8.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.92e-1)" "unprognostic (3.67e-1)" "unprognostic (3.03e-2)" "unprognostic (4.23e-3)" "unprognostic (2.35e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (2.79e-3)" 17.2 8.2 1.0 1.2 1.2 0.2 15.6 0.8 1.6 30.4 2.3 45.5 8.4 74.5 19.1 21.2 58.5 13.0 15.4 0.7 1.5 2.6 1.2 37.2 0.5 0.7 1.2 49.1 3.7 1.8 0.8 4.3 0.7 7.7 12.3 5.7 9.9 10.8 6.6 9.2 21.6 25.3 0.7 16.1 19.1 7.5 1.8 1.6 8.0 17.1 3.1 32.3 18.5 1.1 0.3 0.0 0.7 0.0 55.7 18.8 1.7 11.1 5.0 2.7 4.6 0.0 1.2 0.0 0.7 2.1 1.5 9.1 0.1 0.8 2.3 0.0 0.0 0.0 15.6 0.1 57.2 0.0 0.0 3.6 0.7 1.7 0.9 19.9 4.9 0.0 0.0 0.5 75.0 0.0 0.0 0.1 7.7 0.1 0.0 0.0 8.8 7.3 24.6 0.0 0.7 0.0 0.1 0.1 0.0 20.8 0.0 0.0 71.0 0.0 1.8 0.1 2.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.0 1.2 0.8 1.6 0.7 1.5 0.7 1.2 0.7 0.7 1.8 1.1 2.0 0.0 1.5 20.2 0.5 6.1 0.5 0.4 0.6 0.8 0.5 10.8 4.3 0.0 0.1 3.7 4.2 0.2 0.2 0.2 0.0 0.1 42.5 0.7 13.7 3.9 0.0 0.0 37.0 0.2 6.6 38.7 0.5 0.5 1.3 0.3 0.4 0.0 3.3 0.0 42.9 0.1 0.0 0.0 17.5 11.4 96.6 13.6 10.6 45.9 0.0 13.8 0.0 11.6 23.3 0.4 0.2 82.0 0.0 0.1 0.0 0.5 0.1 0.5 39.5 4.8 22.4 0.4 0.4 1.1 4.8 0.3 0.8 0.1 0.1 0.1 MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 32.8;Plasma cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 201.8;intermediate monocyte: 178.8;myeloid DC: 158.8;non-classical monocyte: 138.4;plasmacytoid DC: 187.5" "Group enriched" "Detected in all" 5 "dendritic cells: 187.5;monocytes: 201.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" 35.8 21.4 5.3 54.6 6.4 83.6 24.8 6.6 5.9 19.6 18.5 30.3 31.0 21.8 9.0 19.8 19.9 28.4 16.0 4.9 7.4 17.3 23.7 46.8 52.1 10.3 6.7 16.7 39.7 16.6 9.9 24.6 9.5 20.5 22.6 1.6 35.2 14.9 12.1 28.9 33.6 20.2 8.9 70.1 32.7 6.4 9.7 23.1 16.3 9.4 39.3 35.6 16.7 12.4 52.4 26.3 26.4 31.3 85.8 57.3 74.0 37.9 79.2 33.1 32.4 21.3 21.4 56.9 44.9 30.4 9.4 40.1 13.6 25.6 15.7 28.5 41.6 19.8 13.6 34.9 43.5 131.6 130.2 68.5 49.2 18.5 23.3 35.6 31.7 21.1 25.6 41.9 17.8 40.9 17.9 74.2 21.9 26.2 32.8 40.8 36.1 28.8 38.9 59.8 8.2 25.5 37.7 32.0 63.0 15.8 49.4 80.0 42.0 44.8 18.4 44.0 36.2 55.4 65.5 28.0 30.4 127.5 51.2 12.2 201.8 29.7 31.9 178.8 35.4 32.9 28.9 29.0 158.8 26.4 15.4 15.9 29.4 13.2 138.4 187.5 30.7 150.3 5.3 6.4 6.6 5.9 4.9 7.4 10.3 6.7 9.5 8.9 9.7 12.4 1.6 6.4 7.5 8.5 25.1 3.6 2.0 2.7 14.2 2.6 1.9 1.0 0.9 2.8 2.0 1.8 0.0 2.5 20.5 2.0 1.9 1.7 3.7 1.4 2.5 3.1 1.8 9.4 7.8 2.3 2.8 7.2 20.9 1.3 1.3 3.4 1.8 0.8 8.4 0.0 6.4 0.9 0.0 15.4 24.7 11.1 3.7 32.8 1.8 17.8 11.0 1.5 9.2 3.5 13.4 1.5 2.5 4.5 78.1 2.5 3.8 1.5 3.9 4.0 13.1 2.3 2.0 0.6 1.6 11.5 3.3 2.7 9.4 2.7 2.0 2.0 MAN2B2 KIAA0935 ENSG00000013288 "Mannosidase alpha class 2B member 2" Q9Y2E5 4 6575189-6623362 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "Secreted to blood" NA NA 15000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "unprognostic (1.30e-1)" "unprognostic (3.32e-1)" "unprognostic (1.28e-1)" "prognostic favorable (7.59e-4)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (2.38e-2)" "unprognostic (2.72e-1)" "unprognostic (6.53e-2)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-3)" "unprognostic (2.18e-1)" 20.0 13.6 12.9 13.8 18.2 14.8 16.4 7.7 14.3 17.6 26.0 14.5 13.4 18.6 14.1 11.3 17.7 15.9 22.6 13.2 15.6 15.1 23.7 18.2 13.5 13.0 13.2 26.6 22.0 9.2 17.9 12.9 11.8 18.0 7.9 5.2 16.7 11.5 4.7 13.6 15.8 10.3 10.6 17.7 20.1 4.4 15.0 9.0 23.2 4.7 8.5 19.3 15.9 11.9 17.5 15.6 2.9 21.0 44.7 30.9 19.7 35.0 40.5 16.8 22.9 9.0 32.3 8.7 16.5 38.2 39.2 17.4 1.0 11.1 9.2 10.4 8.8 11.7 10.9 10.2 19.5 22.0 51.8 41.0 10.9 13.4 3.6 30.3 19.7 10.8 5.1 21.9 22.1 10.8 10.9 13.9 3.8 21.8 11.9 10.7 14.4 10.4 8.8 17.4 5.0 5.5 23.4 13.9 8.9 10.0 27.7 29.1 36.3 30.3 9.1 38.2 22.5 9.0 8.4 4.2 35.4 25.5 26.7 15.4 9.0 14.3 11.7 13.2 8.9 4.2 7.0 10.7 8.6 4.4 6.3 8.2 11.0 6.8 17.5 3.3 10.7 11.0 12.9 18.2 7.7 14.3 13.2 15.6 13.0 13.2 11.8 10.6 15.0 11.9 9.8 16.0 18.9 7.8 11.6 5.0 5.5 4.9 11.4 8.9 8.2 5.6 17.0 20.0 11.1 11.0 6.2 13.5 12.9 18.3 1.9 9.7 0.6 18.7 15.8 8.2 7.8 5.7 9.4 10.7 10.2 18.4 11.7 36.8 10.8 11.1 17.5 44.1 20.9 10.1 8.3 11.0 2.0 30.2 8.2 1.1 19.6 18.0 3.6 8.4 11.2 13.0 5.2 6.0 8.9 10.1 9.0 24.5 15.1 7.1 11.7 4.2 9.5 7.4 13.1 7.5 8.5 1.1 0.6 8.0 3.8 8.5 15.6 4.4 8.9 4.6 MAN2C1 "MANA, MANA1" ENSG00000140400 "Mannosidase alpha class 2C member 1" Q9NTJ4 15 75355207-75368612 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040627, HPA067407" Uncertain Enhanced Nucleoplasm NA NA 110000 "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA040627: AB_10795490, HPA067407: AB_2685834" "unprognostic (4.68e-2)" "unprognostic (1.95e-1)" "unprognostic (3.84e-3)" "unprognostic (3.48e-2)" "unprognostic (3.85e-1)" "unprognostic (3.00e-2)" "unprognostic (1.26e-2)" "unprognostic (6.26e-2)" "unprognostic (2.47e-1)" "unprognostic (5.02e-2)" "unprognostic (1.06e-2)" "unprognostic (3.40e-2)" "unprognostic (4.87e-3)" "unprognostic (9.56e-2)" "unprognostic (1.33e-1)" "unprognostic (2.91e-1)" "unprognostic (1.39e-3)" 49.3 66.1 20.2 23.9 21.1 37.6 49.3 17.7 28.8 52.1 18.6 41.8 25.5 49.3 12.1 29.9 50.5 16.4 55.6 20.0 17.8 52.8 50.0 50.3 20.3 22.8 18.1 58.5 49.1 26.3 56.6 21.1 20.9 49.4 14.9 14.8 37.3 19.5 58.5 36.8 41.6 18.6 17.5 54.7 46.0 34.8 19.8 17.1 64.8 24.5 12.7 45.7 41.5 22.0 11.0 25.5 21.3 15.7 23.8 20.4 27.1 25.3 23.5 12.9 10.9 20.3 38.3 5.7 14.6 18.6 11.8 33.0 11.7 17.1 8.4 30.8 26.1 34.0 58.5 18.1 35.3 23.1 5.7 25.3 17.0 12.3 15.3 27.3 30.9 16.9 20.5 27.4 10.7 22.1 11.9 25.2 9.0 13.2 11.8 16.0 11.0 34.6 16.8 49.8 13.2 22.7 16.4 23.9 11.5 15.6 26.1 26.1 61.5 27.1 18.7 19.0 25.5 27.9 7.1 9.3 17.6 25.9 27.6 4.0 19.8 3.5 9.2 23.0 9.1 3.2 6.9 6.8 22.6 2.6 9.5 6.9 2.2 6.0 18.9 9.2 10.2 14.3 20.2 21.1 17.7 28.8 20.0 17.8 22.8 18.1 20.9 17.5 19.8 22.0 34.1 22.4 51.7 29.0 12.5 13.5 15.2 13.0 11.4 30.7 18.2 16.3 2.8 5.7 19.2 9.2 54.2 17.2 17.2 22.4 3.9 11.4 10.4 10.1 18.3 23.2 34.2 7.6 28.9 8.7 10.9 20.4 39.3 12.7 31.7 46.8 32.5 22.4 20.4 28.6 23.8 19.5 12.2 29.8 20.2 14.0 23.3 26.3 16.0 15.0 31.4 17.3 19.6 18.1 19.5 11.2 20.0 12.4 12.9 16.0 27.9 15.9 19.3 52.4 26.3 25.6 16.3 21.1 10.4 14.9 8.5 21.2 16.2 17.0 24.0 15.3 MANBA ENSG00000109323 "Mannosidase beta" O00462 4 102630770-102760994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 74.0;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.6" "Group enriched" "Detected in many" 5 "dendritic cells: 5.3;granulocytes: 16.6;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;hTCEpi: 13.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053478 Approved Supported Vesicles NA NA 15000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 57: B-cells - Immune response" Vesicles "HPA053478: AB_2682165" "unprognostic (2.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.80e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (7.78e-2)" "unprognostic (1.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (7.12e-2)" "unprognostic (4.81e-2)" "unprognostic (2.13e-1)" 7.1 12.4 1.9 1.5 2.4 7.0 6.4 4.7 2.2 6.5 2.2 6.7 1.6 6.1 0.2 3.8 6.3 1.3 6.6 1.1 2.1 4.8 4.7 10.5 2.1 3.8 2.9 8.8 8.3 3.0 5.0 3.7 4.7 4.3 1.1 2.7 8.9 2.0 3.0 4.5 8.5 2.4 3.0 12.0 9.1 1.6 3.5 1.2 7.1 0.1 2.0 8.1 5.8 3.7 2.9 1.4 0.6 1.6 15.5 12.1 0.9 1.1 6.9 1.8 4.1 1.7 1.0 3.6 1.4 2.7 3.9 1.0 3.0 2.2 1.1 2.2 0.7 3.0 1.1 0.7 2.7 2.8 8.2 3.7 13.7 7.6 3.4 8.9 3.0 1.2 3.6 2.0 3.4 1.4 2.0 2.3 1.3 1.9 1.1 1.9 1.6 0.6 3.4 2.3 1.4 0.5 1.4 1.9 1.5 5.4 4.5 1.8 0.2 2.0 1.3 9.3 1.2 1.3 5.8 0.5 3.1 1.5 1.6 4.0 6.8 16.6 0.4 6.1 0.7 1.7 0.0 0.7 5.3 2.1 0.4 0.6 6.1 1.8 9.1 1.2 0.5 3.1 1.9 2.4 4.7 2.2 1.1 2.1 3.8 2.9 4.7 3.0 3.5 3.7 6.4 32.1 35.6 24.5 45.4 5.9 8.4 13.2 12.0 6.2 11.6 8.1 14.6 14.3 13.5 9.2 6.2 42.3 14.3 5.1 1.9 8.1 2.8 6.9 6.9 8.1 1.8 19.7 36.4 2.7 7.3 13.8 25.5 12.8 34.8 5.5 10.4 17.7 43.6 6.7 66.5 10.5 2.0 58.5 29.6 1.6 9.0 74.0 0.0 111.5 52.8 5.2 17.5 31.2 66.8 5.5 17.3 19.9 17.5 7.5 5.2 9.8 5.8 7.5 0.0 10.8 6.7 0.2 1.4 12.6 4.5 22.6 16.9 12.6 11.2 9.7 MANEAL FLJ31434 ENSG00000185090 "Mannosidase endo-alpha like" Q5VSG8 1 37793847-37801137 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 16.5;Enteroendocrine cells: 30.5;Horizontal cells: 26.9;Inhibitory neurons: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063423 Approved "Golgi apparatus" "Intracellular and membrane" NA NA 47000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" "HPA063423: AB_2685011" "unprognostic (8.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (7.92e-2)" "prognostic favorable (5.28e-4)" "prognostic unfavorable (3.32e-4)" "unprognostic (3.02e-1)" "unprognostic (1.03e-2)" "unprognostic (7.67e-2)" "unprognostic (6.27e-3)" "unprognostic (1.08e-1)" "unprognostic (1.17e-3)" "unprognostic (8.29e-3)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (2.26e-1)" 1.1 7.1 16.3 2.1 16.7 0.2 5.0 12.3 18.2 2.9 4.6 6.1 3.5 1.9 6.5 4.7 2.8 1.3 1.3 16.6 21.4 3.6 9.1 3.0 1.2 16.1 17.0 1.2 10.1 5.9 19.3 0.9 20.0 4.2 6.3 13.3 3.6 2.7 4.0 4.1 3.5 2.3 11.9 1.9 4.6 2.7 20.1 1.3 5.6 2.6 1.9 2.3 2.4 13.6 24.0 30.1 5.4 57.1 7.3 2.7 51.7 4.4 26.0 22.1 9.6 50.3 55.0 40.0 18.8 3.1 26.1 5.4 11.1 5.9 7.9 47.5 23.7 29.4 25.5 41.0 0.5 42.3 23.4 0.9 30.6 1.2 1.1 30.7 0.6 7.1 17.5 30.4 3.5 47.8 11.9 0.1 18.1 57.0 31.8 18.2 39.0 46.2 13.1 62.8 139.8 42.4 63.0 2.0 23.6 1.0 27.3 4.4 3.5 31.0 19.0 30.2 41.0 43.6 45.0 13.1 5.1 13.7 23.2 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 16.3 16.7 12.3 18.2 16.6 21.4 16.1 17.0 20.0 11.9 20.1 13.6 1.1 3.2 2.7 0.3 1.0 0.5 1.1 0.3 2.2 16.5 4.3 4.3 1.1 1.5 0.6 3.7 4.2 0.2 1.1 2.3 0.0 1.6 0.2 1.1 0.7 0.8 30.5 0.0 9.0 6.0 2.0 1.0 1.1 2.5 0.0 1.8 0.0 5.0 0.9 26.9 12.1 3.7 0.0 0.8 0.4 0.0 0.3 0.5 3.6 3.7 0.0 5.0 0.0 9.5 2.7 2.4 2.3 0.0 2.4 1.7 1.1 0.4 0.2 9.5 0.0 0.7 0.4 0.0 1.5 1.5 0.0 0.1 0.7 0.5 4.1 1.3 MANF "ARMET, ARP" ENSG00000145050 "Mesencephalic astrocyte derived neurotrophic factor" P55145 3 51385291-51389397 "Plasma proteins, Predicted secreted proteins" "Stress response, Unfolded protein response" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 426.1;Syncytiotrophoblasts: 459.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 109.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011175 Approved Supported "Endoplasmic reticulum" "Secreted to blood" NA NA 7500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA011175: AB_1845039" "unprognostic (2.90e-2)" "unprognostic (5.24e-2)" "unprognostic (1.11e-2)" "unprognostic (2.51e-2)" "unprognostic (5.84e-2)" "prognostic unfavorable (9.58e-6)" "prognostic unfavorable (7.48e-4)" "unprognostic (7.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.12e-3)" "unprognostic (1.35e-1)" "unprognostic (3.01e-1)" "unprognostic (1.21e-2)" "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (1.27e-1)" "unprognostic (5.10e-2)" 39.4 36.7 34.4 70.9 34.5 35.3 41.8 37.8 50.5 59.4 44.2 55.4 42.5 48.2 169.3 53.2 42.8 32.1 51.1 34.8 42.7 48.6 109.2 44.3 50.5 38.4 35.7 28.7 81.1 38.8 56.4 59.9 37.2 51.3 58.8 17.7 51.0 50.5 12.4 36.6 39.5 47.2 36.2 56.1 59.5 43.2 37.9 47.7 117.8 20.8 76.1 67.8 35.5 38.1 128.6 61.2 164.7 207.7 107.8 139.4 173.8 200.2 160.6 194.0 184.5 99.6 292.6 271.6 162.6 121.9 449.8 77.7 201.4 200.0 187.3 128.9 92.2 220.2 93.5 230.3 349.8 108.2 137.1 60.6 168.5 201.3 271.7 189.9 252.7 112.3 48.3 299.5 181.6 75.5 184.8 215.6 144.6 298.0 237.6 76.4 105.3 288.7 162.8 86.9 64.4 201.6 165.3 104.2 130.3 175.8 83.7 141.2 129.3 117.4 112.1 140.4 222.6 247.9 105.0 186.5 195.4 217.5 221.2 73.2 15.3 9.4 28.8 13.0 35.5 17.4 20.2 27.5 16.0 12.1 14.9 16.0 8.5 26.0 8.3 109.8 13.4 16.9 34.4 34.5 37.8 50.5 34.8 42.7 38.4 35.7 37.2 36.2 37.9 38.1 55.9 32.1 21.5 5.2 134.1 163.1 223.7 232.5 31.3 15.1 50.5 40.5 69.3 61.5 104.0 55.2 6.2 188.1 142.8 75.7 43.0 172.6 99.0 73.3 101.9 88.3 116.6 26.1 5.8 124.6 387.0 101.2 71.9 99.4 62.9 77.9 79.6 156.1 179.5 11.8 8.5 235.9 118.0 36.1 170.6 123.3 60.0 63.0 181.5 7.5 79.1 39.6 117.4 5.0 9.5 167.8 90.5 51.6 426.1 245.0 47.7 78.9 71.1 19.1 65.7 59.7 194.2 176.8 91.1 42.8 160.5 459.0 94.8 40.6 120.9 202.0 MANSC1 "FLJ10298, LOH12CR3" ENSG00000111261 "MANSC domain containing 1" Q9H8J5 12 12326056-12350242 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 70.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "neutrophil: 98.3" "Lineage enriched" "Detected in many" 39 "granulocytes: 98.3" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 50.7;OE19: 54.3;RPTEC TERT1: 25.9" "Low region specificity" "Detected in all" "HPA007955, HPA007956" Approved Approved "Golgi apparatus,Vesicles" NA NA 44000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Vesicles" "HPA007955: AB_1079306, HPA007956: AB_1079305" "unprognostic (5.41e-3)" "unprognostic (3.10e-2)" "unprognostic (1.24e-1)" "unprognostic (5.46e-3)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.63e-2)" "unprognostic (8.47e-2)" "unprognostic (9.18e-2)" "unprognostic (5.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.03e-1)" "prognostic favorable (3.30e-5)" "unprognostic (1.15e-2)" "unprognostic (4.46e-2)" "unprognostic (3.65e-1)" "unprognostic (1.03e-2)" 18.9 12.1 3.4 4.3 4.1 3.5 19.5 3.9 6.5 16.9 5.0 22.9 11.7 22.1 11.5 42.3 16.6 10.2 11.2 4.1 3.0 13.2 9.7 12.3 2.3 3.2 3.3 11.3 25.2 11.3 17.9 9.5 3.2 15.1 15.8 5.4 70.0 10.8 4.0 21.7 15.2 12.1 2.6 11.3 21.5 8.4 3.8 1.4 13.8 4.4 6.4 16.3 20.6 4.0 0.3 5.7 1.8 0.1 5.6 5.5 6.2 3.9 4.6 2.0 2.5 4.8 18.2 0.0 4.2 3.9 2.1 0.8 7.1 3.3 1.5 0.0 6.9 8.3 6.4 4.2 0.9 1.4 2.3 3.5 5.3 1.3 0.9 13.8 50.7 0.1 5.6 0.1 0.6 11.0 0.0 0.6 6.5 54.3 3.0 0.2 0.0 0.1 25.9 18.8 2.6 10.3 2.1 16.9 6.0 2.8 15.4 5.0 20.5 2.8 2.3 0.7 5.5 0.4 0.2 2.8 2.0 0.0 2.1 6.6 1.2 1.0 0.1 0.9 0.0 0.2 0.3 0.0 0.6 0.4 2.5 0.4 98.3 0.6 0.4 0.1 0.0 0.6 3.4 4.1 3.9 6.5 4.1 3.0 3.2 3.3 3.2 2.6 3.8 4.0 29.0 9.6 21.2 8.8 3.3 4.0 7.1 7.2 6.2 6.1 21.2 13.5 2.6 28.6 11.9 23.9 8.4 35.4 4.5 33.6 1.9 19.0 0.9 15.1 5.2 28.8 21.7 3.6 16.6 37.9 7.4 10.4 23.0 20.5 2.5 8.6 37.1 9.8 8.0 10.1 13.5 33.4 8.2 5.5 0.7 2.2 13.7 2.0 0.0 15.0 2.7 11.4 9.2 7.5 11.4 16.3 25.2 16.6 1.0 7.4 16.7 3.0 18.1 13.1 0.0 4.8 6.5 2.1 1.5 22.1 4.7 17.0 3.0 9.7 26.5 8.8 MAP1A MAP1L ENSG00000166963 "Microtubule associated protein 1A" P78559 15 43510958-43531620 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 325.5" "Cell type enhanced" "Detected in many" "dendritic cells: 90.9;Horizontal cells: 299.5;Peritubular cells: 76.3" "Cancer enhanced" "Detected in many" "glioma: 18.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 61 "plasmacytoid DC: 10.5" "Lineage enriched" "Detected in single" 61 "dendritic cells: 10.5" "Cell line enhanced" "Detected in many" "ASC diff: 60.7;BJ hTERT+: 61.8;fHDF/TERT166: 94.0;hTEC/SVTERT24-B: 58.1;U-87 MG: 121.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039063, HPA039064, HPA066488" Enhanced Approved Cytosol No No 55000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA039063: AB_2676327, HPA039064: AB_10673302, HPA066488: AB_2685676" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.86e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-2)" "unprognostic (5.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.65e-2)" "unprognostic (1.13e-3)" "unprognostic (8.36e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (6.59e-5)" "unprognostic (5.83e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (1.09e-5)" "prognostic unfavorable (1.66e-5)" 7.2 6.0 65.3 3.8 78.6 0.9 4.4 39.5 325.5 8.0 0.0 16.5 1.2 8.2 2.4 3.0 7.2 4.2 15.5 92.8 37.5 1.2 0.2 2.2 1.0 201.4 41.4 5.0 1.0 2.0 11.7 2.7 186.0 4.8 3.5 21.7 2.5 7.5 4.5 3.2 4.0 13.1 22.5 0.9 4.3 3.8 85.8 24.0 4.1 5.1 0.9 11.9 4.5 156.7 0.3 2.5 11.1 6.4 60.7 41.5 0.1 36.3 61.8 10.5 10.1 4.4 0.1 0.2 15.3 94.0 3.3 0.5 15.0 0.1 6.1 5.5 1.4 14.2 3.5 0.3 5.8 0.4 5.8 31.3 0.1 58.1 0.3 15.8 8.0 41.3 24.0 0.3 42.8 0.5 26.6 0.8 8.1 0.0 1.0 7.2 32.1 0.1 0.2 0.1 34.8 10.6 1.2 0.1 0.3 14.6 2.3 0.6 1.5 33.7 11.3 11.3 0.5 0.0 1.6 5.0 121.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.1 0.1 65.3 78.6 39.5 325.5 92.8 37.5 201.4 41.4 186.0 22.5 85.8 156.7 6.7 3.2 1.1 11.8 2.2 5.5 1.4 1.4 2.8 43.4 1.7 3.6 55.1 0.0 7.9 3.7 25.0 0.3 90.9 1.0 0.0 0.4 13.1 33.2 19.5 5.7 11.4 3.0 34.4 0.0 0.6 46.9 2.6 1.0 7.0 16.7 4.2 0.0 2.4 299.5 45.1 1.7 10.2 0.3 7.4 5.6 51.0 9.4 8.8 12.2 0.7 16.7 0.0 9.5 51.4 0.7 0.0 76.3 1.1 0.5 0.0 0.5 63.6 27.2 32.9 45.7 48.2 10.6 25.6 1.1 4.1 1.1 5.6 3.1 1.4 0.5 MAP3K9 "MEKK9, MLK1, PRKE1" ENSG00000006432 "Mitogen-activated protein kinase kinase kinase 9" P80192 14 70722526-70809534 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.7;retina: 9.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.6;Inhibitory neurons: 58.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000942 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli" "HPA000942: AB_1079360" "unprognostic (1.20e-1)" "unprognostic (3.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.16e-3)" "unprognostic (2.45e-2)" "unprognostic (3.75e-5)" "unprognostic (2.58e-1)" "unprognostic (4.20e-2)" "unprognostic (4.38e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (4.23e-6)" "unprognostic (5.71e-3)" "unprognostic (6.86e-3)" "unprognostic (1.79e-1)" "unprognostic (2.35e-1)" 0.2 1.0 3.3 1.0 4.6 0.7 1.3 10.7 22.7 0.9 0.4 1.5 1.5 0.4 1.5 5.1 1.0 0.4 0.5 4.0 3.2 1.4 0.7 1.9 1.4 8.6 3.0 0.6 2.2 2.7 1.1 0.6 7.7 0.9 1.5 9.6 1.7 0.5 0.8 4.0 1.4 0.2 0.3 0.9 1.6 5.5 10.0 0.9 2.7 0.4 3.6 0.7 1.8 6.8 22.3 10.5 2.0 2.5 0.0 0.0 6.7 0.5 0.3 2.1 1.9 7.8 8.6 4.5 2.8 0.1 4.7 10.3 6.5 12.8 2.2 3.0 1.7 0.2 4.1 5.2 0.3 0.5 0.9 0.1 6.5 1.5 12.7 3.7 0.0 4.1 1.7 1.0 0.5 9.4 3.7 0.5 4.2 9.0 4.5 1.3 3.9 0.9 4.6 10.9 13.8 3.0 6.3 7.7 1.2 3.7 6.9 0.8 0.0 0.0 8.5 0.0 3.5 2.2 5.6 2.4 3.4 0.4 1.4 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.2 0.2 0.0 0.0 0.2 0.0 3.3 4.6 10.7 22.7 4.0 3.2 8.6 3.0 7.7 0.3 10.0 6.8 0.3 6.4 13.4 6.8 3.9 8.7 13.7 9.4 6.8 17.7 11.2 4.8 2.3 14.3 12.4 7.3 12.5 2.8 1.7 5.7 1.9 6.1 19.8 7.4 0.7 0.8 8.4 0.0 49.6 4.8 1.6 1.0 4.1 8.5 1.3 1.8 1.1 4.8 1.2 30.3 58.1 4.0 4.1 0.8 1.9 20.0 0.6 0.8 3.6 5.6 0.4 3.2 0.0 8.5 1.3 11.1 3.9 0.0 2.8 15.8 2.6 2.8 7.1 12.7 0.0 0.8 1.3 8.0 8.4 12.6 9.1 4.0 3.7 6.0 5.8 27.9 MARCOL ENSG00000248109 "MARCO like" A0A1B0GUY1 5 148221650-148243580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "HeLa: 808.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.2 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 808.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 85.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.3 0.1 0.1 0.3 0.2 0.3 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911020 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: AB_2686722" "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 11.3 13.8 12.6 21.1 16.1 24.0 16.8 8.1 16.3 18.5 10.8 25.9 26.1 14.6 7.7 51.8 16.6 14.1 20.9 14.9 9.3 13.9 13.1 17.0 21.5 11.8 9.3 12.0 22.4 19.4 19.8 14.9 11.5 20.5 22.4 8.8 27.0 13.1 20.8 40.9 25.1 16.3 7.3 24.1 20.9 10.6 9.5 23.2 19.5 13.7 24.0 19.3 25.0 17.9 52.0 34.1 26.6 28.6 14.6 18.6 35.2 20.8 20.0 29.5 22.3 34.1 49.5 37.8 35.6 20.8 32.0 57.5 26.9 28.7 24.6 26.7 20.9 40.7 23.9 20.3 17.0 45.9 51.4 10.9 36.8 27.0 21.4 13.5 24.7 33.6 35.7 36.5 19.5 64.4 49.3 29.9 31.7 36.0 24.2 39.9 20.4 39.7 19.1 39.8 37.9 25.4 34.7 90.2 24.3 28.9 65.1 26.4 22.7 30.3 19.1 39.6 23.4 24.5 28.8 36.7 20.1 23.2 25.3 1.4 0.7 2.1 1.3 0.7 2.1 0.9 1.0 1.3 1.0 1.6 0.8 0.9 3.6 1.6 1.1 0.9 0.6 0.7 12.6 16.1 8.1 16.3 14.9 9.3 11.8 9.3 11.5 7.3 9.5 17.9 17.3 6.4 6.8 29.7 18.5 25.2 21.1 9.1 19.4 26.8 30.0 18.2 12.8 27.1 11.9 20.2 8.4 26.0 33.4 90.3 1.9 20.2 0.6 29.5 15.8 14.7 29.9 14.7 43.6 21.4 20.6 11.7 27.0 41.0 17.2 21.1 13.6 13.0 17.9 20.2 30.3 39.9 10.2 26.7 18.5 0.9 12.8 25.0 3.6 29.0 17.0 18.8 36.0 31.7 51.8 27.3 39.4 10.9 15.6 30.4 33.4 8.1 14.5 18.1 19.7 19.6 13.1 9.1 18.4 39.9 34.4 65.0 23.6 16.0 33.6 44.3 MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 120.0;heart muscle: 116.1;liver: 183.4" "Cell type enhanced" "Detected in some" "Astrocytes: 28.1;Cardiomyocytes: 38.1;Cholangiocytes: 20.0;Endometrial stromal cells: 30.6;Fibroblasts: 16.4;Hepatic stellate cells: 23.2;Hepatocytes: 65.8" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BJ: 133.3;BJ hTERT+: 498.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" No NA 8670000000 1900000000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" 6.3 3.6 9.4 1.3 9.4 0.0 2.8 12.9 7.0 120.0 4.9 57.5 1.9 88.4 3.3 11.1 17.7 5.1 116.1 10.4 27.0 4.8 183.4 6.0 1.0 19.2 16.5 2.7 0.2 0.3 1.0 9.0 15.3 46.0 5.6 0.0 2.3 52.2 37.5 6.3 7.5 44.4 22.2 0.8 1.6 0.5 14.6 0.2 3.2 18.9 4.3 9.9 61.5 32.0 0.0 0.0 0.3 0.4 15.7 17.3 0.1 133.3 498.3 1.8 0.9 0.0 0.0 0.1 0.0 40.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 2.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.2 0.0 0.0 5.4 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 9.4 12.9 7.0 10.4 27.0 19.2 16.5 15.3 22.2 14.6 32.0 1.1 0.0 1.8 28.1 0.2 2.9 0.1 0.2 0.0 0.0 0.0 0.0 38.1 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.9 0.7 30.6 2.0 0.0 0.0 0.2 0.0 0.3 16.4 0.0 0.7 0.0 0.2 23.2 65.8 0.4 0.0 0.9 0.0 0.0 1.9 3.7 7.5 2.5 0.3 1.8 1.0 0.0 0.0 0.0 10.1 0.2 0.0 0.0 0.7 0.1 0.1 0.0 2.4 0.0 0.0 0.0 5.4 4.5 0.0 0.0 0.2 1.7 0.1 0.5 5.1 0.0 0.1 MASP2 MASP1P1 ENSG00000009724 "Mannan binding lectin serine peptidase 2" O00187 1 11026523-11047239 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 64 "liver: 476.5" "Cell type enriched" "Detected in some" 52 "Hepatocytes: 658.6" "Cancer enriched" "Detected in some" 71 "liver cancer: 41.9" "Region enriched" "Detected in single" 9 "cerebellum: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029313, HPA029314" Uncertain Supported "Golgi apparatus" "Secreted to blood" NA NA 340000000 820000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA029313: AB_10669654, HPA029314: AB_10670029" "unprognostic (7.00e-2)" "unprognostic (8.37e-2)" "unprognostic (2.75e-2)" "unprognostic (2.89e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-3)" "prognostic favorable (1.60e-4)" "unprognostic (2.92e-3)" "unprognostic (3.13e-2)" "unprognostic (4.04e-2)" "unprognostic (6.90e-3)" "unprognostic (8.30e-4)" "unprognostic (7.14e-2)" "unprognostic (3.91e-1)" "unprognostic (2.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-4)" 2.1 1.2 0.0 1.7 0.0 7.4 2.2 6.4 0.7 2.4 0.0 2.7 1.6 2.8 0.0 1.2 2.7 1.2 1.3 0.1 0.0 1.0 476.5 1.8 2.7 0.0 0.0 2.9 2.9 0.0 2.3 0.6 0.2 1.6 0.0 6.9 2.5 0.0 5.1 5.3 3.4 0.0 0.0 2.5 2.4 1.5 0.0 0.0 1.9 0.0 0.0 2.1 1.6 0.4 0.5 0.3 2.6 1.6 0.0 0.1 0.4 0.7 0.0 0.0 0.0 1.2 1.0 2.3 0.6 0.0 0.5 0.7 0.0 0.0 0.0 0.6 2.3 1.3 2.7 16.4 0.0 2.0 1.5 0.0 0.0 0.1 0.0 1.8 0.0 1.7 0.7 0.5 0.0 0.5 0.6 1.1 0.3 0.2 0.7 1.6 0.9 0.6 0.0 1.3 1.7 0.7 0.9 0.4 0.4 1.6 0.6 1.2 1.2 0.9 0.5 0.8 0.5 0.5 0.9 1.5 0.5 1.7 0.4 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 4.6 1.1 0.9 0.2 0.0 0.6 0.2 0.2 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.9 0.0 5.3 9.5 0.0 0.0 0.1 0.0 0.1 1.3 0.0 8.2 658.6 0.1 0.0 8.3 0.0 0.0 12.6 0.3 0.0 0.0 0.0 1.8 1.9 0.0 0.1 0.0 8.0 10.4 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.7 0.4 0.0 0.7 0.2 0.0 0.0 0.4 0.6 0.0 0.8 0.1 0.0 0.1 MAST4 KIAA0303 ENSG00000069020 "Microtubule associated serine/threonine kinase family member 4" O15021 5 66596361-67169595 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Astrocytes: 519.7;Basal prostatic cells: 507.3;Excitatory neurons: 636.6;Inhibitory neurons: 489.6;Suprabasal keratinocytes: 399.2;Urothelial cells: 676.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 27.7" "Immune cell enhanced" "Detected in many" "basophil: 15.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 33.2;HDLM-2: 43.2;HEL: 35.5;RT4: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000544 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "HPA000544: AB_1079315" "unprognostic (1.77e-2)" "unprognostic (6.24e-2)" "unprognostic (1.80e-1)" "unprognostic (4.99e-3)" "unprognostic (2.83e-2)" "prognostic favorable (5.18e-5)" "unprognostic (9.01e-2)" "unprognostic (1.00e-1)" "unprognostic (2.79e-2)" "unprognostic (9.47e-2)" "unprognostic (5.03e-2)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (1.37e-2)" "unprognostic (2.63e-1)" "unprognostic (2.63e-1)" "unprognostic (3.08e-2)" 14.9 11.0 4.6 4.5 5.2 1.9 11.1 0.9 27.7 12.1 0.0 6.0 5.1 10.0 5.0 27.0 9.4 8.0 29.5 4.2 5.4 12.0 8.4 11.0 4.4 5.0 5.5 16.4 4.6 15.3 4.6 8.8 1.2 7.6 4.1 4.7 11.5 6.6 11.2 14.8 4.5 9.3 1.1 5.0 7.0 10.0 3.3 16.8 6.5 7.2 10.1 16.0 21.2 11.4 14.6 7.8 3.8 0.2 12.4 10.9 9.0 3.2 4.9 1.1 1.0 7.3 3.9 1.0 6.5 2.7 2.9 12.8 11.8 33.2 1.3 43.2 3.8 35.5 4.7 3.1 0.9 0.1 11.9 18.4 17.8 7.1 14.2 13.3 26.2 3.2 3.5 3.9 8.9 12.6 5.1 0.2 2.5 1.2 6.3 1.1 3.3 0.7 3.1 42.9 5.5 4.4 4.3 1.7 0.2 2.7 2.8 0.2 25.2 3.0 4.1 4.6 5.4 9.9 4.8 0.2 7.7 0.1 2.4 15.2 0.3 0.8 0.9 0.4 2.5 2.9 4.0 1.0 0.4 2.5 4.2 1.8 3.5 2.3 0.9 1.0 6.9 1.3 4.6 5.2 0.9 27.7 4.2 5.4 5.0 5.5 1.2 1.1 3.3 11.4 130.2 32.1 53.3 519.7 11.4 368.6 507.3 127.9 114.9 15.9 79.3 38.1 139.1 27.1 78.7 18.4 2.1 40.7 4.9 24.4 37.2 59.0 129.2 35.8 5.3 111.8 32.2 5.5 636.6 115.8 50.0 33.2 28.5 55.3 93.8 19.4 70.6 42.2 5.1 8.4 489.6 18.1 40.7 6.9 33.7 127.4 41.3 9.8 48.0 78.7 2.1 55.2 4.1 165.9 108.4 70.8 27.2 32.7 13.5 355.5 14.8 93.9 57.2 4.5 39.5 15.9 31.1 14.8 9.2 211.7 399.2 137.2 21.0 14.7 16.1 676.4 MATN1 "CMP, CRTM" ENSG00000162510 "Matrilin 1" P21941 1 30711277-30723585 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 1.3;retina: 5.2" "Cell type enhanced" "Detected in some" "B-cells: 4.1;Paneth cells: 1.1" "Cancer enriched" "Detected in single" 4 "thyroid cancer: 1.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028580 Supported "Secreted to extracellular matrix" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 57: B-cells - Immune response" "HPA028580: AB_10601913" "unprognostic (4.71e-2)" "unprognostic (6.92e-2)" "unprognostic (1.73e-2)" "unprognostic (3.75e-6)" "unprognostic (9.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.31e-3)" "unprognostic (2.63e-1)" "unprognostic (1.32e-1)" "unprognostic (2.80e-1)" "unprognostic (7.31e-2)" "unprognostic (5.22e-2)" "unprognostic (4.01e-13)" "unprognostic (8.23e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-2)" "unprognostic (3.42e-2)" 0.0 0.1 0.4 0.3 0.5 0.7 0.0 0.4 0.4 0.5 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.5 0.6 0.4 0.7 0.2 0.0 0.2 0.3 0.7 0.1 0.0 5.2 0.3 0.0 0.0 0.2 0.1 0.0 0.3 0.4 0.1 0.2 0.4 0.0 0.3 0.0 0.0 0.1 0.2 1.3 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.8 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.1 0.3 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.0 0.2 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.0 0.7 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.5 0.4 0.4 0.2 0.4 0.6 0.4 0.7 0.3 0.4 1.3 0.3 0.0 0.5 0.0 4.1 0.1 0.6 0.1 0.0 0.0 0.4 1.0 0.5 0.0 0.6 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.4 0.2 0.3 0.2 0.0 0.0 0.4 0.0 0.1 0.6 0.0 0.3 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 1.1 0.4 0.3 0.2 0.0 0.1 0.0 0.3 0.0 0.5 0.2 0.8 0.5 0.5 0.1 0.3 0.5 0.3 0.0 0.1 MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 201.0;Peritubular cells: 258.8;Theca cells: 297.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Cell line enhanced" "Detected in many" "BJ: 72.5;BJ hTERT+ SV40 Large T+: 78.6;BJ hTERT+ SV40 Large T+ RasG12V: 106.7;HaCaT: 114.4;HBF TERT88: 100.6;SuSa: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" NA NA 1500000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "CAB033879: AB_2141502" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.98e-1)" "unprognostic (5.35e-2)" "unprognostic (7.18e-2)" "unprognostic (5.22e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (6.31e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (6.65e-2)" 54.4 51.0 24.3 30.2 22.5 1.8 43.6 17.6 23.2 194.4 19.3 67.5 58.5 147.0 101.6 32.8 46.9 40.1 110.2 20.0 23.4 39.3 24.6 15.2 18.0 24.1 30.5 116.4 11.3 28.0 9.9 177.9 26.3 104.9 57.8 45.7 42.6 171.9 4.0 62.8 80.6 98.1 18.3 5.9 23.7 31.2 23.4 4.9 271.4 28.5 15.4 103.0 139.2 30.8 24.1 10.8 23.3 2.5 60.7 3.6 15.0 72.5 17.6 78.6 106.7 13.0 8.4 0.1 7.0 29.2 3.5 114.4 2.3 4.4 100.6 0.0 2.9 0.8 6.1 0.9 14.0 0.0 0.0 13.6 9.5 16.1 0.8 22.1 0.5 1.3 0.1 0.2 4.1 11.2 0.0 0.7 7.1 0.3 3.7 0.0 2.4 11.4 5.7 5.3 16.0 1.5 11.5 0.2 19.8 67.3 10.9 1.4 0.6 5.2 31.5 16.1 11.0 0.9 0.2 0.2 18.8 0.4 5.9 0.0 0.1 0.1 0.2 0.4 5.2 0.0 0.7 0.9 0.8 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 24.3 22.5 17.6 23.2 20.0 23.4 24.1 30.5 26.3 18.3 23.4 30.8 27.8 3.2 1.3 11.1 0.3 37.3 10.1 6.2 80.2 6.3 3.8 45.8 29.1 18.6 3.0 16.5 54.2 1.2 0.2 20.6 0.0 9.9 86.0 4.2 22.6 32.4 23.4 3.2 6.4 0.0 1.1 113.1 5.1 5.0 0.0 43.5 201.0 11.0 1.6 0.0 11.5 25.4 0.0 5.0 7.7 108.6 103.5 0.9 28.4 19.7 2.0 8.1 0.0 86.0 59.8 3.2 18.2 258.8 0.0 6.5 118.7 3.4 1.6 52.9 13.1 97.2 17.1 2.5 2.6 7.3 8.5 2.5 2.0 297.5 27.4 1.8 MATN3 "EDM5, HOA" ENSG00000132031 "Matrilin 3" O15232 2 19992052-20012668 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.2;placenta: 11.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 38.5;Sertoli cells: 26.3" "Cancer enhanced" "Detected in all" "pancreatic cancer: 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "Hep G2: 143.4" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 1.7" HPA051250 Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 440000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum, Golgi apparatus" "HPA051250: AB_2681406" "unprognostic (3.47e-1)" "prognostic unfavorable (1.41e-4)" "unprognostic (7.57e-2)" "unprognostic (2.75e-2)" "unprognostic (1.71e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.62e-5)" "unprognostic (1.27e-1)" "unprognostic (4.84e-2)" "unprognostic (7.40e-2)" "unprognostic (3.20e-2)" "unprognostic (2.54e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.51e-1)" "unprognostic (7.04e-2)" "unprognostic (3.15e-2)" 2.2 0.6 5.1 0.5 3.2 0.0 2.7 3.4 5.7 2.5 2.5 0.6 0.4 2.1 0.9 0.5 1.9 2.1 0.4 3.4 3.9 1.9 0.0 13.2 0.3 5.2 6.0 0.7 0.4 0.4 0.3 11.3 5.2 1.6 0.5 0.3 0.6 4.6 0.3 0.8 0.4 1.7 4.7 0.3 1.8 0.9 7.6 0.1 1.3 0.6 0.3 0.8 1.2 3.6 6.4 4.9 16.1 0.1 4.5 9.7 1.0 2.0 1.1 6.5 8.2 4.7 2.7 0.0 0.8 1.7 6.2 1.1 0.4 12.7 9.2 0.0 0.4 0.0 1.1 143.4 1.1 0.0 0.0 21.3 0.7 7.1 1.7 4.5 8.7 0.0 0.0 0.0 13.8 2.5 0.0 0.0 5.0 0.2 2.4 0.0 0.0 0.0 19.5 4.5 0.1 2.1 10.6 1.8 6.5 27.1 19.2 0.1 4.9 9.5 11.4 0.4 1.2 0.1 0.0 0.0 1.6 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 3.2 3.4 5.7 3.4 3.9 5.2 6.0 5.2 4.7 7.6 3.6 1.6 38.5 2.2 0.0 0.0 0.3 0.3 2.6 0.0 0.0 5.4 1.3 0.3 0.0 2.3 1.8 0.0 0.1 0.1 0.0 0.0 0.4 0.4 0.3 0.8 2.8 0.0 0.0 0.1 0.2 1.9 1.9 0.0 0.5 0.0 4.4 0.0 0.0 0.1 0.0 0.2 0.0 4.1 0.0 0.3 0.4 1.5 0.1 3.6 4.7 0.0 0.0 0.0 0.5 0.2 1.1 0.0 4.5 0.0 0.3 0.0 0.8 1.6 0.0 26.3 0.8 6.8 0.0 1.3 0.0 0.1 0.1 0.1 6.3 0.0 0.2 MATN4 ENSG00000124159 "Matrilin 4" O95460 20 45293445-45308529 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "pancreas: 24.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.4;Fibroblasts: 8.5;Langerhans cells: 6.3;Spermatogonia: 4.9;Suprabasal keratinocytes: 4.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 2.5;U-937: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 14000 "Cluster 25: Pancreas - Digestion" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.54e-1)" "unprognostic (2.39e-2)" "unprognostic (2.22e-2)" "unprognostic (3.60e-2)" "unprognostic (8.38e-2)" "unprognostic (9.67e-2)" "unprognostic (1.84e-1)" "unprognostic (6.79e-2)" "unprognostic (6.27e-2)" "unprognostic (6.74e-3)" "unprognostic (5.53e-1)" "unprognostic (6.19e-3)" "unprognostic (3.63e-6)" "unprognostic (2.38e-1)" "unprognostic (4.69e-2)" "unprognostic (4.27e-1)" "unprognostic (5.38e-2)" 0.7 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 24.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.4 0.0 3.2 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.1 0.1 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 2.5 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 6.4 0.7 1.0 0.0 0.0 1.6 1.9 1.1 0.0 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.1 0.7 0.2 0.4 0.0 0.0 1.0 2.5 0.0 8.5 1.1 0.8 0.0 0.3 0.4 0.2 0.1 0.0 0.4 0.1 0.0 0.0 6.3 0.5 0.0 0.1 1.8 1.0 0.0 0.0 0.0 3.0 0.4 0.9 0.1 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.0 0.4 0.4 1.6 4.9 0.3 4.3 0.3 0.3 0.1 0.2 1.0 MATR3 "KIAA0723, MGC9105, MPD2, VCPDM" ENSG00000015479 "Matrin 3" P43243 5 139293674-139331677 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" RNA-binding "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 155.9;Inhibitory neurons: 160.2;Langerhans cells: 122.3;Oligodendrocyte precursor cells: 117.6;Oligodendrocytes: 162.4;Respiratory ciliated cells: 127.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB033552, HPA036564, HPA036565" Supported Approved Nucleoplasm "Intracellular and membrane" NA NA 260000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB033552: AB_2281755, HPA036564: AB_10669907, HPA036565: AB_10673623" "unprognostic (9.33e-2)" "unprognostic (6.57e-2)" "unprognostic (8.37e-2)" "unprognostic (7.53e-2)" "unprognostic (7.20e-2)" "unprognostic (4.32e-3)" "unprognostic (1.03e-1)" "unprognostic (3.56e-2)" "unprognostic (2.96e-2)" "unprognostic (1.93e-1)" "unprognostic (1.23e-1)" "unprognostic (9.36e-2)" "unprognostic (1.08e-3)" "unprognostic (1.73e-1)" "unprognostic (1.93e-1)" "unprognostic (3.86e-2)" "unprognostic (7.90e-2)" 112.9 127.9 145.2 93.6 156.1 323.5 161.0 172.2 224.5 144.1 109.6 106.3 76.9 166.6 124.0 103.3 131.1 115.3 111.4 158.4 146.1 150.1 112.9 115.2 157.9 126.2 132.1 199.3 102.8 168.6 95.1 122.9 131.4 130.2 106.5 223.4 93.5 133.2 119.6 82.0 90.0 142.4 144.8 124.5 89.1 114.9 139.3 221.7 190.5 114.0 170.2 133.5 91.2 156.3 209.0 191.1 559.5 260.7 192.4 212.5 283.2 172.2 300.9 300.4 347.5 273.1 208.8 351.2 236.8 244.1 284.8 135.8 376.8 269.6 403.0 278.4 189.1 236.5 205.0 285.0 183.2 262.5 174.4 222.5 203.7 247.4 226.3 247.1 296.1 219.4 216.9 170.3 313.8 186.7 496.0 285.8 303.6 205.2 182.6 304.7 416.4 217.8 278.0 316.5 279.5 348.7 248.3 176.7 264.6 426.3 194.4 254.5 192.2 272.0 177.7 180.6 246.3 171.0 300.4 423.0 189.8 226.5 268.0 187.0 71.2 116.3 109.6 82.2 134.8 116.3 114.3 124.6 92.6 97.7 124.4 116.5 34.7 150.9 106.7 50.7 136.1 159.8 145.2 156.1 172.2 224.5 158.4 146.1 126.2 132.1 131.4 144.8 139.3 156.3 0.1 44.8 50.2 83.6 17.6 114.6 0.8 99.2 15.9 1.8 0.3 0.3 0.7 0.0 92.0 0.0 2.1 1.2 0.0 27.6 0.0 0.0 0.3 0.2 0.2 13.6 83.5 15.5 155.9 0.0 1.0 17.5 5.1 0.4 100.3 0.1 0.0 0.0 1.3 1.7 160.2 35.3 87.5 0.0 122.3 0.6 0.6 4.7 103.2 60.9 0.1 0.7 0.0 117.6 162.4 0.1 12.4 0.7 7.3 0.7 0.8 0.2 127.9 1.3 0.0 1.0 33.3 1.1 0.5 15.1 111.2 0.8 21.8 0.5 41.9 1.0 MATR3 ENSG00000280987 "Matrin 3" 5 139273752-139331671 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA036564, HPA036565" Supported Approved Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA036564: AB_10669907, HPA036565: AB_10673623" "unprognostic (3.08e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-2)" "unprognostic (2.37e-2)" "unprognostic (3.64e-1)" "unprognostic (1.10e-1)" "unprognostic (8.69e-9)" "unprognostic (1.10e-1)" "unprognostic (9.33e-3)" "unprognostic (3.09e-1)" "unprognostic (2.08e-1)" "unprognostic (5.51e-2)" "unprognostic (9.91e-10)" "unprognostic (2.91e-2)" "unprognostic (9.21e-3)" "unprognostic (2.24e-1)" "unprognostic (9.89e-2)" 10.5 13.5 14.6 24.4 14.6 25.1 31.1 9.9 24.5 9.7 5.5 22.4 16.2 15.3 34.0 17.8 19.2 9.6 30.6 15.4 12.9 10.2 9.7 8.4 36.1 18.4 10.9 14.3 7.5 8.3 2.2 10.3 18.8 15.5 29.3 11.8 26.4 8.6 41.2 20.4 12.1 14.8 13.9 19.9 17.7 18.6 13.5 17.4 9.7 38.4 33.7 14.7 2.8 21.2 81.0 58.9 30.2 162.9 65.9 79.7 58.6 42.8 36.4 69.4 87.0 101.7 71.7 284.8 60.7 61.2 45.0 91.2 257.9 136.3 120.5 48.7 125.6 190.2 100.3 89.8 57.6 176.9 67.9 93.7 95.4 79.6 90.7 38.6 78.9 103.7 143.2 50.3 74.0 31.7 98.5 53.4 122.7 35.4 38.8 199.0 92.8 125.1 40.3 55.7 92.6 56.5 49.4 60.7 113.6 77.3 57.0 71.1 56.3 52.8 78.5 43.7 63.7 23.3 33.6 153.2 45.8 148.1 61.6 0.1 0.8 0.1 0.5 1.2 1.3 3.4 1.7 2.4 3.2 2.0 2.6 1.7 0.2 0.9 0.4 0.1 1.4 1.2 14.6 14.6 9.9 24.5 15.4 12.9 18.4 10.9 18.8 13.9 13.5 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 MAU2 "KIAA0892, mau-2, MAU2L, MGC75361, SCC4" ENSG00000129933 "MAU2 sister chromatid cohesion factor" Q9Y6X3 19 19320829-19358754 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059897 Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nuclear bodies" "HPA059897: AB_2684154" "unprognostic (3.53e-1)" "unprognostic (2.94e-2)" "unprognostic (1.18e-1)" "unprognostic (9.57e-3)" "unprognostic (1.87e-1)" "prognostic favorable (3.90e-5)" "unprognostic (1.68e-2)" "unprognostic (3.49e-3)" "unprognostic (5.56e-3)" "unprognostic (3.56e-1)" "unprognostic (3.98e-3)" "unprognostic (1.28e-1)" "unprognostic (4.27e-3)" "unprognostic (2.42e-2)" "unprognostic (1.10e-1)" "unprognostic (6.67e-3)" "unprognostic (2.96e-2)" 16.2 15.9 15.9 12.6 19.1 21.2 15.8 16.4 19.4 18.8 15.1 17.9 13.1 18.4 11.8 20.2 18.4 10.6 19.6 15.1 15.2 15.1 14.3 14.2 14.6 20.1 17.4 23.4 16.5 13.4 21.1 12.2 18.7 17.6 7.6 10.9 15.5 12.1 36.0 21.7 16.5 11.2 15.7 22.2 15.0 19.7 17.6 17.4 17.0 17.6 12.0 16.5 17.2 26.1 13.6 10.4 18.0 16.1 14.5 15.1 24.9 12.7 12.9 16.8 15.1 14.8 18.9 16.9 26.7 13.7 8.5 15.9 15.5 12.8 7.8 9.0 39.3 13.0 16.5 13.2 16.8 23.7 19.5 16.7 14.4 12.1 13.8 17.4 16.3 15.0 18.0 20.3 11.3 15.5 24.3 32.5 15.8 18.7 29.1 27.1 11.6 18.2 11.8 17.6 26.0 23.8 15.7 16.2 16.1 9.1 14.0 32.9 14.8 25.9 6.0 25.7 19.3 26.1 23.5 16.9 12.8 24.8 19.9 3.1 5.8 4.3 6.0 5.0 6.8 4.6 5.3 5.7 5.1 4.5 5.6 5.4 10.4 6.5 11.1 4.9 5.4 6.1 15.9 19.1 16.4 19.4 15.1 15.2 20.1 17.4 18.7 15.7 17.6 26.1 16.4 19.2 18.3 33.6 17.3 6.2 5.5 8.5 18.8 30.4 13.1 15.2 19.1 11.5 10.5 11.0 54.2 10.4 16.4 15.8 3.9 8.2 9.7 16.5 17.0 13.4 14.4 17.4 26.1 9.4 7.1 13.0 15.8 14.5 10.1 26.0 14.6 8.6 8.8 50.5 31.8 11.9 4.1 13.8 6.4 12.3 15.2 13.9 10.6 14.0 15.4 12.0 20.6 26.7 55.3 11.8 10.7 13.9 12.8 10.5 13.7 6.2 21.0 29.3 6.6 17.2 14.8 31.9 12.6 11.8 9.7 15.2 13.6 21.1 13.1 8.6 MAZ "Pur-1, ZF87, Zif87, ZNF801" ENSG00000103495 "MYC associated zinc finger protein" P56270 16 29806106-29811164 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048315, HPA059495, HPA065930" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA048315: AB_2680353, HPA059495: AB_2684039, HPA065930: AB_2685579" "unprognostic (1.05e-1)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" "unprognostic (3.83e-1)" "unprognostic (3.25e-3)" "unprognostic (6.16e-2)" "unprognostic (1.27e-1)" "unprognostic (5.12e-2)" "unprognostic (2.00e-1)" "unprognostic (6.39e-3)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.20e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (7.08e-2)" 71.0 91.7 156.7 92.1 153.0 270.3 65.5 147.4 179.9 87.4 125.2 139.4 92.7 90.1 51.4 92.6 88.6 73.6 74.4 158.9 134.8 63.6 101.2 73.2 123.9 140.4 144.6 96.7 105.4 113.3 83.0 61.8 136.6 122.9 101.0 50.8 86.2 75.4 126.2 96.3 87.7 75.8 134.8 97.8 85.5 89.9 143.9 256.0 79.5 93.1 111.2 94.4 68.4 145.2 227.2 294.8 298.8 326.9 158.4 149.6 268.4 161.0 130.6 246.0 177.4 378.5 316.5 402.4 205.2 316.9 121.6 201.3 494.2 210.9 87.5 329.9 792.4 267.7 641.3 526.2 222.1 668.7 318.8 160.7 292.1 207.2 232.5 228.7 249.4 556.7 398.5 343.3 118.3 927.1 644.8 566.3 303.7 246.1 227.6 627.9 281.3 468.5 202.3 242.2 456.1 355.1 153.8 330.1 204.6 190.5 284.3 633.7 172.8 269.8 215.4 103.6 256.1 249.3 344.4 448.5 131.9 435.4 227.9 18.1 14.7 23.9 58.8 24.0 63.6 13.5 39.1 56.5 19.4 10.2 31.6 47.3 11.9 40.1 16.4 19.9 45.8 21.3 156.7 153.0 147.4 179.9 158.9 134.8 140.4 144.6 136.6 134.8 143.9 145.2 52.1 6.4 5.4 9.4 35.3 32.9 14.7 26.7 35.3 61.6 77.8 66.9 0.3 31.5 14.5 11.0 12.5 26.8 106.7 111.5 29.4 31.6 2.5 58.5 59.0 41.0 133.3 90.3 12.8 41.9 55.6 46.3 34.7 39.6 33.0 103.1 30.7 37.7 57.5 47.1 13.0 103.6 32.6 47.8 47.8 6.6 28.0 47.6 46.2 8.4 26.4 35.6 50.4 9.5 14.2 36.3 68.5 36.9 41.6 32.8 37.8 21.9 25.6 35.1 32.9 30.1 49.1 22.2 24.5 38.6 35.5 16.7 67.5 70.9 126.8 14.9 MBD6 KIAA1887 ENSG00000166987 "Methyl-CpG binding domain protein 6" Q96DN6 12 57520710-57530148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "neutrophil: 13.6" "Lineage enriched" "Detected in many" 10 "granulocytes: 13.6" "Cell line enhanced" "Detected in all" "RH-30: 116.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038948, HPA038949" Uncertain Enhanced Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA038948: AB_2676285, HPA038949: AB_10671868" "unprognostic (2.56e-1)" "unprognostic (4.15e-2)" "unprognostic (1.64e-2)" "unprognostic (3.12e-2)" "unprognostic (1.13e-1)" "unprognostic (2.84e-1)" "unprognostic (2.84e-2)" "unprognostic (6.96e-2)" "unprognostic (2.74e-2)" "unprognostic (3.19e-1)" "unprognostic (1.83e-2)" "unprognostic (6.65e-2)" "unprognostic (1.28e-3)" "unprognostic (1.13e-1)" "unprognostic (1.73e-1)" "unprognostic (2.24e-1)" "unprognostic (1.01e-2)" 32.8 40.0 18.7 34.5 22.1 57.1 36.5 19.5 21.3 43.3 21.9 38.8 41.6 46.9 17.9 35.8 40.7 19.1 25.8 17.7 22.8 38.8 44.2 34.4 26.1 24.1 20.8 43.8 44.5 23.0 105.0 25.6 20.0 38.6 20.7 38.5 46.9 27.1 34.1 37.8 44.9 19.8 17.2 64.9 42.6 57.5 25.0 27.9 110.2 18.8 18.8 34.3 35.0 26.8 22.7 31.7 24.2 26.0 16.6 11.9 33.9 25.7 15.8 16.6 12.3 33.0 35.3 22.8 19.3 14.0 16.2 31.3 22.3 19.4 11.6 45.2 22.5 40.2 33.4 22.8 20.3 24.2 99.7 20.8 33.7 17.8 24.8 25.1 22.3 19.3 26.1 58.7 13.5 23.3 25.3 23.9 23.3 16.7 23.2 24.6 116.7 17.7 14.3 44.4 33.3 20.2 20.5 40.6 25.0 14.2 45.7 38.7 21.9 17.8 29.0 18.2 17.4 60.5 22.4 15.7 23.2 15.1 30.6 0.0 1.0 0.4 1.3 0.9 0.5 1.3 0.2 0.4 0.5 0.8 0.5 0.5 13.6 0.7 0.4 0.3 0.2 0.6 18.7 22.1 19.5 21.3 17.7 22.8 24.1 20.8 20.0 17.2 25.0 26.8 24.7 6.4 17.8 12.4 14.1 11.0 13.4 11.9 22.2 55.5 27.5 22.4 6.2 25.8 13.0 9.2 27.1 12.4 12.6 20.6 5.9 9.4 13.3 18.9 19.7 16.7 15.6 18.7 5.4 12.0 8.8 12.2 29.0 32.8 19.0 21.7 14.6 24.3 14.0 25.2 6.6 20.5 8.2 23.8 11.0 9.4 14.6 23.1 12.4 15.0 9.1 30.4 11.3 6.6 8.1 9.2 20.7 12.8 14.8 12.3 20.8 4.4 16.3 69.4 19.7 14.9 17.3 51.7 30.8 23.7 12.4 22.6 16.8 16.9 16.8 15.8 MBL2 "COLEC1, MBL" ENSG00000165471 "Mannose binding lectin 2" P11226 10 52765380-52772784 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2810 "liver: 280.9" "Cell type enriched" "Detected in some" 66 "Hepatocytes: 238.5" "Cancer enriched" "Detected in single" 275 "liver cancer: 22.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "Hep G2: 2.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "basal ganglia: 1.1" "HPA002027, CAB016782" Enhanced "Secreted to blood" NA NA 1220000000 1900000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB016782: , HPA002027: AB_1079324" "unprognostic (1.72e-2)" "unprognostic (3.03e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 280.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 238.5 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 MBNL1 "EXP, EXP35, EXP40, EXP42, KIAA0428, MBNL" ENSG00000152601 "Muscleblind like splicing regulator 1" Q9NR56 3 152243828-152465780 "Disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 537.7;Oligodendrocytes: 471.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016398, HPA035098" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "CAB016398: AB_784435, HPA035098: AB_2674461" "unprognostic (5.46e-3)" "unprognostic (6.01e-3)" "unprognostic (1.94e-3)" "unprognostic (1.99e-1)" "unprognostic (3.44e-2)" "unprognostic (5.82e-3)" "unprognostic (2.75e-2)" "unprognostic (9.49e-3)" "unprognostic (5.18e-2)" "unprognostic (1.70e-2)" "unprognostic (2.78e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (7.53e-3)" "unprognostic (6.15e-2)" "unprognostic (1.77e-1)" "unprognostic (2.98e-1)" 116.4 35.8 18.2 105.0 24.9 90.4 48.1 22.9 22.3 76.9 18.9 69.0 43.6 68.0 30.1 65.3 38.4 75.2 63.2 18.7 23.0 31.5 47.6 78.1 138.4 25.5 20.1 45.1 24.3 26.5 11.8 29.9 26.0 55.1 71.1 17.7 32.3 66.0 188.8 61.5 58.3 116.5 25.0 92.3 40.5 14.9 25.2 108.4 31.8 131.0 135.1 78.4 32.7 32.5 133.8 107.8 17.3 38.9 132.5 135.8 12.7 163.3 131.5 105.6 87.8 48.0 76.3 136.3 81.3 230.8 32.8 59.7 32.1 94.5 155.0 106.9 43.7 149.3 52.2 22.7 73.8 180.5 104.5 63.8 50.2 121.9 94.0 80.8 219.5 54.1 77.3 180.5 103.6 45.9 169.0 66.0 7.2 38.9 85.4 170.5 53.0 171.6 53.7 66.3 13.8 15.7 71.1 38.2 69.8 6.2 53.1 270.5 186.6 143.6 55.1 96.4 142.7 186.9 115.9 154.6 83.8 220.6 79.1 95.3 53.7 90.1 79.4 61.7 84.4 56.2 64.5 66.5 70.1 49.7 80.6 70.7 78.4 79.6 54.7 24.9 62.6 104.3 18.2 24.9 22.9 22.3 18.7 23.0 25.5 20.1 26.0 25.0 25.2 32.5 175.5 150.6 193.7 179.2 252.1 213.6 49.0 25.9 156.0 28.5 51.8 48.0 179.8 52.9 89.5 38.6 64.6 26.1 266.0 164.7 21.5 36.0 2.6 64.0 92.2 142.9 47.3 160.2 258.6 63.6 9.2 122.9 78.0 68.5 162.6 31.5 90.0 91.5 60.9 32.0 185.5 68.8 14.2 216.4 195.5 9.7 89.5 235.0 103.2 537.7 249.4 18.2 230.7 224.7 471.9 57.3 90.3 71.5 181.3 61.2 121.4 42.2 63.1 84.1 98.6 102.7 145.6 4.3 12.7 149.4 243.6 14.8 340.1 46.8 80.7 50.1 MBTPS1 "KIAA0091, PCSK8, S1P, SKI-1" ENSG00000140943 "Membrane bound transcription factor peptidase, site 1" Q14703 16 84053761-84116942 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 318.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056109 Supported NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA056109: AB_2683040" "unprognostic (1.50e-1)" "unprognostic (9.73e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (2.50e-1)" "unprognostic (2.02e-1)" "unprognostic (1.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "prognostic favorable (2.21e-5)" "unprognostic (2.62e-1)" "unprognostic (2.92e-1)" "unprognostic (6.63e-2)" "unprognostic (6.88e-2)" 45.8 33.7 12.7 26.2 16.4 24.6 42.8 17.6 13.3 41.2 18.1 38.7 26.0 40.8 25.6 28.2 45.6 32.2 44.6 13.1 17.8 36.7 27.5 35.5 27.5 6.3 8.0 49.4 36.4 58.5 38.8 37.1 8.9 37.3 33.7 108.7 42.4 40.3 18.9 27.8 26.4 41.2 5.9 30.1 30.7 19.6 16.5 33.4 53.9 35.6 29.9 35.2 21.3 8.6 49.4 61.3 53.8 75.2 124.2 100.1 42.2 81.2 124.4 70.2 52.6 43.7 71.0 47.0 82.0 117.3 55.8 52.9 50.2 56.3 77.9 42.6 55.9 34.4 55.8 61.3 59.9 84.2 72.7 103.6 79.9 64.8 55.5 100.3 92.4 62.2 45.6 40.3 43.1 85.0 46.6 46.4 50.3 27.7 43.2 59.6 28.7 34.1 56.1 40.2 41.0 51.2 156.9 42.9 62.1 58.3 134.3 76.4 99.0 72.3 52.5 43.7 38.7 50.5 102.6 90.5 52.6 50.6 45.2 8.0 16.3 15.0 16.3 13.8 16.8 11.3 14.0 15.4 12.8 9.6 16.9 15.3 4.5 17.0 11.6 7.1 9.6 18.3 12.7 16.4 17.6 13.3 13.1 17.8 6.3 8.0 8.9 5.9 16.5 8.6 54.3 48.1 50.7 27.1 33.5 13.8 24.2 25.9 19.9 68.4 62.2 56.1 50.5 44.3 41.9 25.8 166.8 24.4 41.0 28.9 11.7 24.1 0.9 70.4 67.8 39.8 34.9 19.4 50.4 27.5 21.4 48.4 23.0 92.7 29.1 103.1 36.0 33.8 16.7 84.1 53.5 26.6 28.5 21.0 10.8 5.5 53.4 23.3 19.6 36.5 22.5 44.4 29.9 57.8 39.0 30.2 24.8 50.4 59.3 30.1 20.3 17.5 56.4 318.6 26.3 60.9 42.2 12.6 24.2 23.4 15.8 21.6 34.3 75.5 33.8 28.6 MCCC1 MCCA ENSG00000078070 "Methylcrotonoyl-CoA carboxylase 1" Q96RQ3 3 183015218-183116075 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 153.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008310 Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA008310: AB_1853620" "unprognostic (4.01e-2)" "unprognostic (1.83e-3)" "unprognostic (2.05e-2)" "unprognostic (2.59e-3)" "unprognostic (3.46e-2)" "unprognostic (4.16e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-3)" "unprognostic (2.57e-3)" "unprognostic (9.82e-2)" "unprognostic (9.74e-2)" "unprognostic (7.65e-2)" "prognostic favorable (3.68e-4)" "unprognostic (4.73e-1)" "unprognostic (2.21e-1)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" 37.9 22.6 9.5 9.5 10.9 13.9 33.2 9.9 13.4 12.3 13.8 17.4 16.1 10.1 14.6 17.6 12.2 11.9 34.2 9.2 9.3 58.8 59.3 17.9 11.7 9.5 9.1 17.2 31.2 18.7 8.4 6.3 10.6 15.1 18.6 10.8 18.0 13.4 21.9 12.2 13.8 10.6 9.3 11.8 21.7 9.1 11.1 16.0 18.9 26.3 15.5 26.5 9.4 13.3 43.1 16.5 10.3 10.6 42.6 19.1 20.4 19.5 26.4 21.1 23.5 22.9 17.1 47.6 31.0 17.2 35.8 22.0 15.4 12.9 26.4 16.6 17.0 40.0 18.3 23.9 28.7 27.5 22.0 21.6 14.5 10.0 23.3 14.0 28.6 40.7 22.7 24.7 23.6 35.4 27.1 15.9 11.2 66.3 17.9 22.4 22.6 60.1 32.2 67.2 22.0 16.4 75.3 100.1 21.1 10.7 153.9 37.8 14.0 15.8 12.5 12.8 28.6 24.3 48.8 48.2 16.8 38.4 15.2 14.4 13.3 25.0 10.7 15.6 12.3 17.9 14.1 11.8 26.6 15.4 14.7 13.1 2.1 25.4 16.8 17.3 9.6 10.7 9.5 10.9 9.9 13.4 9.2 9.3 9.5 9.1 10.6 9.3 11.1 13.3 6.2 9.6 53.9 44.7 14.6 7.0 20.1 17.9 15.9 13.0 10.6 9.5 32.8 31.5 20.2 27.6 10.4 35.4 6.3 7.2 33.2 25.3 5.4 11.0 10.2 6.6 6.0 10.9 66.6 17.2 5.4 10.3 21.4 21.9 7.6 19.0 6.1 36.5 16.5 8.4 56.9 13.6 16.2 11.1 8.6 5.5 8.7 10.5 7.2 44.0 10.5 12.0 4.1 47.7 61.6 13.4 15.8 10.5 12.5 10.4 13.5 40.6 21.4 11.2 6.6 11.6 9.6 8.1 4.4 22.3 5.8 28.3 10.1 24.3 20.5 21.7 MCCD1 ENSG00000204511 "Mitochondrial coiled-coil domain 1" P59942 6 31528962-31530232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 73 "kidney: 81.8" "Group enriched" "Detected in some" 44 "Distal tubular cells: 401.1;Proximal tubular cells: 414.8" "Group enriched" "Detected in some" 5 "breast cancer: 0.7;endometrial cancer: 0.8;liver cancer: 2.4;renal cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.34e-1)" "unprognostic (2.39e-2)" "unprognostic (2.71e-1)" "unprognostic (3.22e-2)" "prognostic favorable (1.73e-4)" 0.0 0.0 0.1 0.0 0.2 0.1 1.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 81.8 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.1 0.3 0.4 0.1 0.4 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 401.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 414.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 MCEE "GLOD2, MCE" ENSG00000124370 "Methylmalonyl-CoA epimerase" Q96PE7 2 71109684-71130239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 92.0;Proximal tubular cells: 77.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035196 Approved Nucleoli "Intracellular and membrane" No No 29000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoli "HPA035196: AB_10601871" "unprognostic (7.65e-2)" "unprognostic (8.20e-2)" "unprognostic (3.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.35e-1)" "prognostic favorable (4.76e-4)" "prognostic favorable (5.78e-4)" "unprognostic (4.86e-3)" "unprognostic (6.48e-2)" "unprognostic (1.08e-1)" "unprognostic (7.43e-3)" "unprognostic (8.59e-2)" "unprognostic (9.40e-3)" "unprognostic (4.90e-2)" "unprognostic (3.55e-1)" "unprognostic (6.51e-2)" "unprognostic (5.38e-2)" 17.8 30.0 8.9 12.3 9.7 9.1 32.7 10.5 12.5 22.1 15.4 20.1 20.1 13.1 30.5 26.3 14.8 14.2 35.9 8.9 9.4 33.7 69.8 13.7 14.7 9.5 9.1 18.5 36.1 35.6 24.1 17.6 9.9 23.9 23.9 12.3 42.8 17.8 36.5 28.4 16.9 12.2 9.7 16.0 23.5 6.0 9.4 13.3 14.1 61.7 15.5 16.5 21.9 11.7 12.1 5.2 10.6 7.6 34.3 46.6 30.2 18.5 23.3 9.2 13.9 14.7 14.8 18.7 5.5 18.5 7.0 12.5 12.4 9.6 9.5 17.1 10.7 12.7 16.3 42.5 19.5 14.5 10.3 31.3 13.5 6.2 12.3 20.5 10.6 14.6 17.1 31.9 9.1 15.5 10.9 16.9 9.6 33.1 14.6 12.8 12.3 35.2 14.8 10.4 11.9 8.8 6.9 40.1 18.1 12.1 31.7 13.4 13.7 10.6 8.3 10.9 7.5 30.7 13.1 20.0 17.5 23.7 9.9 20.3 23.2 27.6 15.4 25.6 21.9 21.6 19.3 15.5 19.9 16.7 17.6 15.0 6.1 16.5 25.3 23.9 35.3 14.6 8.9 9.7 10.5 12.5 8.9 9.4 9.5 9.1 9.9 9.7 9.4 11.7 11.1 25.6 13.4 13.7 12.8 8.5 10.5 18.4 21.6 2.6 37.5 27.3 75.2 25.8 18.2 5.5 2.1 36.2 11.2 14.0 92.0 13.3 1.1 17.2 16.2 9.0 9.0 12.0 13.3 18.4 36.8 23.3 17.3 20.2 0.0 5.2 12.8 73.0 15.1 5.0 14.5 32.5 18.3 10.4 8.7 1.0 29.2 9.4 14.2 14.0 9.1 7.3 5.2 16.1 20.8 9.6 16.2 17.7 42.0 11.0 35.0 77.1 19.4 8.6 26.3 12.7 17.9 3.7 5.1 25.6 20.9 11.4 10.1 16.9 23.0 11.9 MCF2 "ARHGEF21, DBL" ENSG00000101977 "MCF.2 cell line derived transforming sequence" P10911 X 139581770-139708227 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 29.5;seminal vesicle: 17.0;testis: 18.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 98.0;Excitatory neurons: 27.8;Inhibitory neurons: 36.2;Oligodendrocyte precursor cells: 20.6;Theca cells: 22.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "U-251 MG: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.42e-1)" "unprognostic (2.18e-2)" "unprognostic (1.46e-2)" "unprognostic (5.11e-4)" "unprognostic (8.95e-2)" "unprognostic (3.99e-2)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "unprognostic (1.80e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-2)" "unprognostic (7.77e-2)" "unprognostic (2.33e-3)" "unprognostic (3.68e-2)" "unprognostic (2.92e-2)" "unprognostic (4.62e-4)" "unprognostic (4.02e-2)" 0.2 29.5 5.8 0.4 4.5 0.7 0.1 6.4 8.8 0.0 1.7 0.1 0.0 0.1 12.3 0.0 0.8 0.7 1.0 4.4 7.0 1.5 0.2 0.1 0.6 9.1 7.4 10.2 0.2 0.0 3.4 0.0 9.7 1.2 0.0 9.2 1.0 17.0 0.1 0.1 0.3 0.0 5.5 1.1 0.2 18.6 14.1 0.5 1.1 0.2 0.1 0.2 0.1 5.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.5 3.1 0.0 0.5 0.6 2.5 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.3 0.6 37.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.8 4.5 6.4 8.8 4.4 7.0 9.1 7.4 9.7 5.5 14.1 5.9 0.2 0.0 0.0 3.6 0.3 0.1 0.3 0.2 0.6 2.2 0.6 0.4 1.8 0.0 0.0 0.0 98.0 0.0 0.3 0.1 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.0 27.8 0.0 0.0 0.7 0.0 0.1 0.0 2.2 0.4 0.2 0.1 0.0 36.2 0.0 0.0 0.6 0.3 2.5 1.2 0.2 0.0 4.7 1.4 1.0 4.1 20.6 7.6 0.1 0.0 8.2 0.1 0.4 0.0 0.6 0.0 2.4 0.0 0.1 0.4 0.6 0.8 0.1 0.0 0.0 0.3 22.8 0.0 0.2 MCF2L "ARHGEF14, DBS, KIAA0362, OST" ENSG00000126217 "MCF.2 cell line derived transforming sequence like" O15068 13 112894378-113099742 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 134.5" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Bipolar cells: 70.4;Cone photoreceptor cells: 127.2;Endothelial cells: 69.7;Microglial cells: 92.8;Oligodendrocytes: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 35.9;SCLC-21H: 65.3;SH-SY5Y: 29.0;SK-BR-3: 43.9;WM-115: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.56e-1)" "unprognostic (2.53e-2)" "unprognostic (8.86e-3)" "prognostic favorable (6.01e-4)" "unprognostic (9.07e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.02e-2)" "unprognostic (1.94e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.36e-5)" "unprognostic (1.17e-1)" "prognostic favorable (9.14e-6)" "unprognostic (2.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.24e-1)" "prognostic favorable (2.63e-5)" 44.1 7.6 39.0 6.3 35.1 0.9 39.5 134.5 76.1 16.5 0.4 17.5 11.3 19.4 5.1 14.1 17.8 13.4 52.8 32.3 27.7 17.5 7.7 19.0 6.8 51.3 40.6 4.8 18.8 10.3 44.4 8.4 57.6 17.0 13.7 20.0 32.7 8.5 16.5 24.8 18.7 7.1 29.1 3.6 18.1 2.0 49.3 7.1 27.6 16.3 6.0 15.0 16.9 47.7 0.0 1.6 14.9 4.8 0.5 0.9 2.1 0.0 0.0 0.0 0.0 3.8 2.2 0.1 3.7 1.5 2.5 0.3 3.8 0.0 0.0 0.0 7.4 4.3 0.2 9.1 0.5 0.2 3.1 1.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.2 14.4 5.6 0.5 2.6 4.0 35.9 0.0 0.2 15.0 7.9 5.9 23.6 65.3 29.0 0.0 43.9 0.1 2.4 26.0 0.1 0.6 0.1 12.5 5.4 0.0 7.5 0.4 2.3 23.9 1.0 60.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.4 39.0 35.1 134.5 76.1 32.3 27.7 51.3 40.6 57.6 29.1 49.3 47.7 138.3 0.0 8.4 4.6 2.6 5.5 3.4 1.5 8.0 70.4 12.9 10.0 44.3 12.8 4.6 9.2 127.2 0.0 1.2 10.8 7.9 5.6 0.4 9.9 1.6 69.7 26.5 0.0 58.5 2.6 0.2 7.1 23.0 18.7 1.3 11.2 13.6 3.4 1.4 38.7 60.9 54.6 8.2 2.2 4.6 1.5 0.6 2.5 8.8 92.8 0.1 5.4 0.0 40.7 75.0 1.7 9.8 1.2 3.0 4.2 4.0 10.4 7.2 23.9 0.0 5.2 11.9 0.7 2.7 4.2 9.1 0.1 2.1 0.5 7.4 4.1 MCFD2 "F5F8D, LMAN1IP, SDNSF" ENSG00000180398 "Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit" Q8NI22 2 46901870-46941855 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 253.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022410, HPA034593" Supported "Intracellular and membrane" NA NA 1200000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "CAB022410: , HPA034593: AB_2674239" "unprognostic (1.16e-2)" "unprognostic (5.71e-3)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (2.50e-1)" "unprognostic (2.87e-2)" "unprognostic (3.98e-2)" "unprognostic (3.10e-2)" "unprognostic (3.93e-2)" "unprognostic (8.32e-2)" "unprognostic (1.56e-3)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.64e-4)" 52.0 155.5 41.3 35.6 43.1 34.7 55.1 38.1 40.3 50.4 69.5 32.2 32.5 54.5 42.1 45.9 41.9 44.9 42.3 41.3 46.8 59.4 111.8 45.0 32.1 33.5 41.3 79.2 104.1 52.5 38.7 70.1 41.6 54.0 26.9 83.3 149.7 82.9 83.3 26.0 33.4 52.5 28.0 44.6 33.9 30.9 48.6 30.8 121.0 84.6 34.2 41.2 29.2 34.7 147.7 86.9 74.7 59.7 151.5 215.1 115.4 248.4 254.1 129.4 116.8 116.9 109.4 96.4 297.7 294.7 154.3 81.8 67.0 127.0 207.7 64.5 67.2 101.9 87.1 182.5 236.5 94.8 158.6 163.2 77.8 206.7 178.7 247.9 210.8 28.0 199.3 56.0 266.8 48.7 56.9 67.6 63.9 102.3 84.1 68.3 133.2 106.7 80.3 59.3 23.9 62.2 93.1 46.9 116.0 86.3 33.1 80.6 341.1 298.3 130.5 97.0 164.2 42.0 43.8 76.4 320.2 88.0 100.8 27.2 21.4 29.7 9.6 23.3 12.2 12.5 10.9 10.2 18.4 12.8 14.3 9.8 12.0 9.9 18.3 16.9 9.7 14.0 41.3 43.1 38.1 40.3 41.3 46.8 33.5 41.3 41.6 28.0 48.6 34.7 50.8 105.8 89.1 16.6 29.6 48.2 56.5 65.3 36.5 69.3 64.4 48.5 70.3 38.6 68.8 47.8 39.6 75.5 25.4 26.6 21.5 88.6 144.3 76.4 60.2 64.7 26.8 28.2 19.6 178.5 64.5 70.1 20.4 69.9 50.5 44.1 53.9 155.1 54.5 38.7 23.8 28.5 18.3 40.5 31.3 113.7 62.7 39.2 12.4 7.5 33.8 253.2 12.3 16.1 16.2 152.7 23.1 59.5 43.8 82.4 42.2 41.3 69.6 51.3 65.7 63.9 55.4 48.9 32.6 39.6 44.9 102.1 23.4 74.3 22.8 75.8 MDFI I-mfa ENSG00000112559 "MyoD family inhibitor" Q99750 6 41636882-41654244 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 221.7;Extravillous trophoblasts: 113.7;Pancreatic endocrine cells: 134.9;Syncytiotrophoblasts: 138.7;Urothelial cells: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 80.5;HBEC3-KT: 117.2;OE19: 100.0;REH: 315.3" "Region enriched" "Detected in many" 7 "cerebellum: 17.0" "Low region specificity" "Detected in all" HPA049973 Approved Approved Nucleoplasm NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 14: REH - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA049973: AB_2680975" "unprognostic (9.74e-3)" "unprognostic (4.25e-2)" "unprognostic (6.82e-2)" "unprognostic (6.26e-3)" "unprognostic (9.18e-2)" "unprognostic (1.07e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.32e-5)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.66e-1)" "unprognostic (3.27e-2)" "unprognostic (4.04e-2)" "prognostic unfavorable (2.85e-6)" "unprognostic (2.66e-2)" "unprognostic (6.06e-2)" "unprognostic (1.57e-1)" "unprognostic (8.22e-2)" 33.0 4.3 3.9 5.7 4.2 0.2 23.1 4.1 5.8 23.2 4.3 2.5 1.7 5.8 1.2 44.7 10.0 12.8 8.8 3.5 4.3 5.5 1.5 18.6 1.7 8.2 5.8 15.6 3.2 1.6 9.1 11.0 6.3 14.3 0.4 0.1 22.4 2.2 0.9 15.4 3.2 2.5 3.6 0.3 4.6 5.0 4.6 1.5 4.6 1.1 2.5 13.6 27.1 4.2 60.1 0.2 50.4 0.1 0.1 0.0 80.5 0.0 0.0 0.0 0.0 0.0 28.2 0.1 18.2 0.0 0.3 48.4 13.8 117.2 0.0 0.0 0.0 0.4 0.0 2.5 2.2 0.0 0.3 3.6 53.3 0.6 24.6 0.0 38.4 16.1 0.2 0.3 0.0 0.0 41.8 0.4 34.4 100.0 1.6 315.3 29.6 0.5 3.3 9.2 9.4 23.2 0.6 43.1 0.0 34.5 0.2 4.0 40.3 0.1 44.1 0.5 1.7 0.1 0.3 0.1 0.3 2.8 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.2 4.1 5.8 3.5 4.3 8.2 5.8 6.3 3.6 4.6 4.2 1.8 0.0 0.0 0.0 0.0 24.5 48.6 36.8 12.0 0.5 18.9 16.9 0.9 0.0 8.2 5.5 0.0 221.7 0.2 0.4 0.0 33.8 0.5 0.5 1.7 12.7 0.0 0.0 0.1 51.2 113.7 12.8 0.0 0.7 0.0 10.0 7.9 0.1 19.6 0.0 0.3 1.2 6.1 0.0 4.5 0.5 39.1 0.4 0.0 2.8 0.6 0.0 0.0 4.5 0.2 134.9 0.0 6.0 0.0 55.6 0.0 0.0 3.5 0.0 0.0 19.7 9.1 0.1 7.9 10.7 9.1 138.7 0.6 2.7 0.3 73.5 MDGA1 "GPIM, MAMDC3" ENSG00000112139 "MAM domain containing glycosylphosphatidylinositol anchor 1" Q8NFP4 6 37630679-37699306 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 79.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.0;Cone photoreceptor cells: 50.1;Horizontal cells: 57.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 9 "cerebellum: 79.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031235, HPA050382" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Golgi apparatus" "HPA031235: AB_10603017, HPA050382: AB_2681108" "unprognostic (4.67e-2)" "unprognostic (6.97e-3)" "unprognostic (3.24e-1)" "unprognostic (5.69e-4)" "unprognostic (2.75e-2)" "unprognostic (2.41e-1)" "unprognostic (1.45e-2)" "unprognostic (2.00e-1)" "unprognostic (2.02e-2)" "unprognostic (1.45e-1)" "unprognostic (2.16e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-5)" "unprognostic (9.19e-3)" "unprognostic (5.28e-3)" "unprognostic (3.80e-3)" "unprognostic (4.60e-2)" 2.6 2.9 4.2 2.6 3.9 0.3 1.6 79.9 5.3 5.4 0.0 2.6 0.5 3.4 1.8 3.7 2.7 3.2 2.3 8.8 4.9 1.2 0.6 3.1 2.6 4.3 4.7 6.5 2.4 4.1 4.8 0.3 7.4 2.1 1.1 4.0 1.1 1.3 1.1 4.9 2.8 2.5 1.0 3.1 2.0 1.5 2.1 0.8 1.4 1.7 2.1 1.9 4.4 3.2 0.2 3.5 4.8 2.4 12.3 4.3 2.2 2.8 2.2 3.5 3.2 0.0 0.0 0.7 0.5 1.7 3.0 5.4 0.5 0.0 1.0 4.9 3.4 0.0 0.3 0.0 0.5 0.0 1.1 1.0 0.0 1.4 0.0 6.8 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.0 0.1 0.4 5.9 1.7 0.0 0.8 3.7 4.3 0.0 1.5 0.3 2.6 0.2 3.1 0.6 0.3 3.4 1.4 1.2 4.3 0.0 0.1 0.0 4.2 1.0 2.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.1 4.2 3.9 79.9 5.3 8.8 4.9 4.3 4.7 7.4 1.0 2.1 3.2 3.0 9.6 0.5 12.7 2.0 2.3 2.4 0.7 1.2 34.0 0.4 0.6 5.7 1.5 0.8 3.7 50.1 0.2 3.1 0.0 0.0 0.5 2.6 0.6 1.8 1.6 1.8 0.0 4.9 0.0 1.4 4.4 0.5 0.5 0.0 1.1 1.4 0.0 0.1 57.2 4.9 0.0 0.0 0.3 1.1 0.2 10.2 0.3 1.8 1.9 0.0 2.6 4.1 4.0 2.1 0.6 0.0 4.9 1.7 2.0 0.0 0.5 1.9 2.0 0.0 2.6 3.0 2.1 1.3 2.8 3.0 0.7 2.9 0.2 0.0 5.1 MDK "FLJ27379, MK, NEGF2" ENSG00000110492 Midkine P21741 11 46380756-46383837 "Cancer-related genes, Predicted secreted proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 529.1" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 1010.4;Granulosa cells: 726.2;Paneth cells: 1272.7;Proximal enterocytes: 883.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.8;neutrophil: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 888.4;REH: 1343.8;SH-SY5Y: 1093.6" "CAB010055, HPA057126" Uncertain Approved Vesicles "Secreted to blood" NA NA 158000 960000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB010055: AB_627949, HPA057126: AB_2683344" "unprognostic (8.87e-3)" "unprognostic (6.65e-2)" "unprognostic (4.02e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.90e-1)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.11e-2)" "unprognostic (4.01e-2)" "unprognostic (4.15e-1)" "prognostic unfavorable (3.06e-6)" "unprognostic (8.78e-2)" "unprognostic (1.31e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" 41.1 98.0 23.3 22.9 23.3 11.7 82.2 27.0 37.0 379.4 16.3 78.0 263.3 208.2 60.3 38.1 170.3 140.0 36.1 21.6 40.7 35.9 8.5 48.5 20.3 31.8 27.5 529.1 30.5 103.9 370.4 32.0 22.6 128.7 38.0 5.9 137.4 84.1 7.6 26.9 211.3 49.5 24.6 78.1 108.3 16.8 31.5 92.9 26.8 9.8 15.9 84.1 129.3 24.6 51.1 66.5 758.4 2.5 5.2 62.2 18.6 39.2 77.0 145.6 128.8 505.2 219.5 3.4 528.6 58.5 6.3 429.6 431.8 0.7 13.3 157.0 91.6 22.5 5.6 703.6 336.2 1.7 3.5 100.0 13.2 89.2 0.5 31.0 214.3 28.9 385.2 3.5 83.3 348.6 19.8 9.4 888.4 275.9 388.0 1343.8 28.8 4.4 1.8 1.6 418.1 1093.6 128.9 11.3 11.0 665.8 347.3 349.5 59.0 221.1 526.2 3.1 27.2 2.9 11.0 5.1 6.5 13.7 197.3 0.0 0.0 0.0 0.1 0.2 0.0 1.8 0.1 0.2 0.0 0.4 0.0 0.0 2.1 0.1 0.2 0.1 0.9 0.4 23.3 23.3 27.0 37.0 21.6 40.7 31.8 27.5 22.6 24.6 31.5 24.6 108.2 0.0 5.4 5.5 9.6 11.1 162.1 392.4 12.5 1.3 245.2 218.7 7.0 34.3 393.6 47.8 0.0 162.3 5.4 499.0 1.9 286.0 26.4 134.6 490.2 115.0 1010.4 2.5 2.1 104.5 123.5 275.2 162.1 228.2 4.5 726.2 102.4 4.6 48.3 0.0 1.9 368.8 286.8 4.2 12.0 126.3 109.6 10.0 37.4 7.5 9.4 47.1 0.0 4.5 1.3 221.1 1272.7 18.8 18.6 163.6 883.4 19.6 109.5 1.1 85.5 26.1 197.0 31.8 34.3 26.2 8.1 153.1 11.4 8.9 187.6 511.1 MED20 "DKFZp586D2223, PRO0213, SRB2, TRFP" ENSG00000124641 "Mediator complex subunit 20" Q9H944 6 41905354-41921139 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040717 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 24: B-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Centrosome Nucleoplasm "HPA040717: AB_10794146" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (2.58e-3)" "unprognostic (8.32e-2)" "unprognostic (9.86e-3)" "unprognostic (1.72e-1)" "unprognostic (1.16e-3)" "unprognostic (1.22e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (1.58e-3)" "unprognostic (4.23e-2)" "unprognostic (5.10e-2)" "prognostic favorable (1.17e-4)" "unprognostic (1.71e-2)" "unprognostic (4.63e-1)" "unprognostic (4.13e-3)" "unprognostic (2.31e-1)" 8.1 11.8 6.3 7.7 7.3 6.1 10.9 9.1 8.0 10.6 7.9 10.6 10.5 9.7 13.5 9.8 9.9 7.7 11.6 6.5 7.1 12.8 10.4 7.4 10.0 6.6 6.6 8.2 9.3 10.6 6.4 13.6 7.0 11.2 11.8 5.9 8.7 10.2 14.5 9.7 8.7 12.0 5.8 9.2 9.7 7.4 7.2 12.7 11.9 16.6 13.3 10.2 7.6 9.0 28.5 23.0 25.7 32.1 23.1 24.8 31.7 18.2 17.1 25.9 20.5 29.5 20.3 41.4 34.3 23.0 15.5 22.0 39.7 26.4 31.2 22.2 14.7 37.5 19.6 28.6 23.9 30.5 22.2 18.6 36.8 22.5 33.3 19.6 33.9 36.4 49.0 19.3 32.7 25.7 36.3 22.3 35.1 93.5 19.3 48.0 29.4 15.1 34.9 19.9 23.7 18.6 25.3 12.6 26.5 28.7 24.7 32.4 33.2 18.2 38.9 11.4 22.5 19.3 27.1 85.7 9.9 33.3 26.3 18.7 24.9 18.4 10.7 29.4 14.0 19.0 7.3 12.2 26.1 23.6 9.4 11.3 9.3 17.4 20.7 23.5 14.4 16.7 6.3 7.3 9.1 8.0 6.5 7.1 6.6 6.6 7.0 5.8 7.2 9.0 4.4 9.6 3.9 2.3 6.6 3.7 4.2 7.2 6.8 2.4 7.0 5.1 5.2 2.8 6.8 7.3 0.0 22.7 7.3 6.6 7.9 6.9 0.6 5.1 7.1 4.2 9.6 8.0 2.8 3.3 18.6 5.0 6.1 6.7 7.0 8.3 8.6 8.3 8.7 1.7 2.8 5.6 14.2 6.3 2.6 0.7 3.4 3.7 1.8 4.7 6.3 3.7 7.2 5.5 3.0 4.9 3.1 6.8 5.7 4.7 5.8 10.1 4.6 4.2 0.0 3.6 4.9 8.3 13.6 5.8 5.7 24.9 3.0 7.1 7.2 5.4 MED24 "CRSP100, CRSP4, DRIP100, KIAA0130, MED5, THRAP4, TRAP100" ENSG00000008838 "Mediator complex subunit 24" O75448 17 40019097-40061215 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 178.1;Club cells: 100.6;Ionocytes: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 244.1;SK-BR-3: 283.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (3.93e-2)" "unprognostic (1.65e-1)" "unprognostic (4.10e-2)" "unprognostic (8.27e-2)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (2.56e-1)" "unprognostic (1.33e-1)" "unprognostic (1.19e-2)" "unprognostic (4.04e-2)" "unprognostic (3.18e-3)" "unprognostic (4.36e-2)" "unprognostic (1.03e-1)" "unprognostic (2.16e-1)" "unprognostic (3.97e-1)" 28.4 30.6 21.6 24.8 23.0 37.3 29.1 20.7 29.2 37.8 18.3 29.5 28.6 33.9 19.0 32.6 31.8 16.8 35.3 24.2 19.0 29.1 25.7 46.5 26.7 18.3 21.2 38.8 25.6 31.2 39.1 23.8 19.5 28.1 24.5 26.4 31.4 17.9 84.0 35.2 30.1 24.3 16.9 30.1 30.5 35.8 19.3 32.7 28.9 48.9 27.9 25.8 30.1 19.6 31.8 63.3 57.3 59.1 38.7 36.1 44.6 41.7 32.5 56.7 50.4 63.1 42.2 65.0 71.6 46.5 28.2 72.8 89.7 244.1 45.3 59.8 147.2 34.0 59.2 84.0 32.2 84.4 63.0 45.0 45.5 56.3 34.1 36.8 75.0 42.8 98.1 41.9 38.6 42.1 93.7 55.2 37.7 36.7 72.4 71.2 45.2 54.5 29.7 36.5 79.9 57.8 43.9 283.0 33.4 49.3 62.4 75.4 45.2 31.1 26.0 34.5 53.6 39.0 41.4 49.5 56.5 42.2 42.7 0.5 4.8 6.0 5.3 6.0 4.2 4.6 3.7 6.1 6.8 4.0 3.5 4.2 0.3 3.5 3.9 2.8 3.9 5.1 21.6 23.0 20.7 29.2 24.2 19.0 18.3 21.2 19.5 16.9 19.3 19.6 14.9 22.4 51.3 13.1 12.7 11.3 25.1 178.1 13.1 11.9 31.4 24.9 16.3 20.0 100.6 23.9 16.7 28.9 8.3 24.8 15.6 15.1 14.8 20.6 10.2 43.3 28.1 27.0 17.6 18.0 23.3 12.2 42.3 27.0 10.8 28.5 9.3 14.8 20.0 10.1 20.3 34.1 99.7 12.0 19.2 8.6 9.9 8.6 14.2 9.4 15.4 10.8 6.2 13.6 13.9 18.5 43.7 9.4 14.2 10.4 23.7 17.6 66.3 11.5 6.6 10.9 13.5 13.4 15.5 12.0 18.6 22.6 10.7 18.0 33.3 28.6 MED28 "DKFZP434N185, EG1, magicin" ENSG00000118579 "Mediator complex subunit 28" Q9H204 4 17614641-17634105 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Actin-binding, Activator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035900, HPA035901" Uncertain Supported Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA035900: AB_10673223, HPA035901: AB_2674853" "unprognostic (1.14e-3)" "unprognostic (6.97e-2)" "unprognostic (1.95e-1)" "unprognostic (6.08e-3)" "unprognostic (8.22e-3)" "unprognostic (3.90e-1)" "unprognostic (1.55e-2)" "unprognostic (5.47e-2)" "unprognostic (5.71e-2)" "unprognostic (2.43e-1)" "unprognostic (2.27e-2)" "unprognostic (7.00e-2)" "unprognostic (1.16e-2)" "unprognostic (6.30e-2)" "unprognostic (8.46e-2)" "unprognostic (1.14e-1)" "unprognostic (5.07e-3)" 6.9 5.6 8.8 7.5 9.3 12.2 9.2 9.4 8.8 12.2 8.8 9.8 5.9 11.5 9.7 7.9 10.6 5.2 6.4 8.4 9.4 7.7 6.2 9.7 10.8 9.4 8.8 14.8 7.3 6.6 10.3 8.5 8.4 9.1 6.9 11.7 9.2 7.3 12.6 10.2 9.6 7.2 8.6 10.2 8.7 6.0 9.6 11.2 9.8 5.9 11.1 9.1 9.9 11.9 4.6 2.9 23.2 11.7 10.0 7.8 9.4 6.5 7.7 8.6 7.8 8.1 10.9 12.6 4.5 6.0 7.6 4.5 14.1 7.0 8.6 5.0 7.0 22.2 10.1 12.3 7.0 15.7 10.7 7.6 9.6 5.4 4.5 9.0 7.5 18.0 20.0 11.3 7.7 4.5 23.3 27.0 16.1 9.1 4.8 17.8 8.5 5.9 8.2 6.8 16.6 8.3 5.7 4.9 5.7 13.6 9.3 16.0 9.4 5.6 3.9 4.0 6.2 8.4 4.0 16.1 5.1 14.9 6.1 5.2 6.6 6.5 4.5 5.2 4.4 5.5 4.9 4.2 6.4 5.6 6.4 5.0 9.0 5.5 4.4 4.4 4.2 7.5 8.8 9.3 9.4 8.8 8.4 9.4 9.4 8.8 8.4 8.6 9.6 11.9 45.7 19.2 27.6 4.9 67.6 92.2 114.0 86.2 46.1 42.6 54.9 65.8 19.5 38.6 55.2 22.0 16.7 114.5 69.9 25.9 84.1 61.6 11.6 31.2 47.3 63.9 44.3 93.2 5.1 53.8 167.8 57.9 19.4 35.5 59.1 78.4 52.5 31.5 93.9 33.7 5.8 41.2 65.1 74.1 103.0 20.4 56.5 61.7 60.5 5.6 115.4 58.9 94.7 9.5 8.9 57.2 47.4 47.0 33.0 110.2 33.6 58.8 40.6 35.1 32.9 50.5 74.7 76.0 100.5 46.0 93.5 134.6 61.3 62.7 47.5 104.6 MEGF10 "KIAA1780, SR-F3" ENSG00000145794 "Multiple EGF like domains 10" Q96KG7 5 127290796-127465737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis, Phagocytosis" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 52.6" "Cell type enhanced" "Detected in some" "Astrocytes: 218.4;Oligodendrocyte precursor cells: 97.5;Oligodendrocytes: 381.7;Skeletal myocytes: 62.9" "Cancer enhanced" "Detected in some" "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 31.6;RH-30: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 73000000 "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (7.02e-2)" "unprognostic (4.50e-2)" "unprognostic (1.02e-1)" "unprognostic (2.26e-3)" "unprognostic (8.91e-3)" "unprognostic (1.59e-2)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.41e-1)" "unprognostic (1.76e-4)" "unprognostic (5.28e-3)" "unprognostic (2.59e-1)" "unprognostic (9.36e-4)" "unprognostic (1.17e-1)" 0.2 1.7 18.0 0.1 34.9 0.0 0.7 29.4 19.9 0.3 0.0 0.8 0.1 0.7 0.4 0.1 0.1 0.0 0.4 15.6 18.2 0.0 0.4 0.0 0.0 26.6 26.8 0.1 0.0 0.0 1.7 0.1 29.4 0.7 0.2 8.0 1.9 1.1 3.0 0.3 0.2 0.3 21.2 0.1 0.1 0.4 23.8 0.6 0.1 4.8 0.2 0.0 0.1 52.6 0.0 0.0 31.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 6.8 0.0 0.2 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.0 3.4 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.7 0.0 0.1 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 34.9 29.4 19.9 15.6 18.2 26.6 26.8 29.4 21.2 23.8 52.6 0.0 0.0 0.0 218.4 0.0 0.0 0.1 0.0 0.0 2.0 0.7 1.5 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 6.5 1.3 0.2 0.0 0.0 4.5 0.0 0.0 0.4 0.0 15.4 0.0 0.7 0.0 0.2 0.0 8.4 3.5 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 29.0 0.0 38.9 1.0 97.5 381.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 2.0 0.0 62.9 0.2 0.4 0.7 0.0 0.1 0.0 0.1 5.1 0.0 0.1 MEGF6 EGFL3 ENSG00000162591 "Multiple EGF like domains 6" O75095 1 3487951-3611508 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 20.6;Basal keratinocytes: 18.4;Basal squamous epithelial cells: 23.3;Melanocytes: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 51.1;HeLa: 56.3;hTERT-RPE1: 69.7;U-2197: 55.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052129 Uncertain Approved "Microtubules,Cytokinetic bridge" "Secreted to blood" Yes No 1700000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Microtubules "Cytokinetic bridge" "HPA052129: AB_2681739" "unprognostic (1.95e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.19e-1)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-3)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (9.51e-2)" "unprognostic (3.43e-2)" 25.9 4.3 2.9 3.9 2.7 10.8 20.0 2.6 2.8 14.5 1.4 14.1 2.1 9.6 1.4 13.2 28.9 11.2 14.2 1.9 3.2 5.9 5.0 22.1 5.5 3.5 5.8 18.0 6.5 0.4 4.1 2.8 3.6 26.5 1.1 1.8 19.3 4.7 4.8 44.6 10.0 1.4 2.1 10.7 10.1 3.3 3.7 3.4 11.6 1.9 3.4 11.0 22.8 1.9 11.6 14.1 4.3 6.6 0.4 0.3 1.0 51.1 14.1 5.2 1.6 3.3 10.4 0.0 13.8 24.6 4.4 6.7 0.0 0.5 1.7 0.0 0.4 0.0 56.3 3.3 0.0 0.2 0.9 0.1 0.6 0.4 0.8 69.7 5.6 0.1 0.0 0.0 0.1 6.0 0.0 10.9 2.7 3.3 0.9 2.2 3.0 6.2 1.1 3.8 3.8 3.1 18.8 1.1 6.4 11.4 4.9 1.5 2.2 19.6 1.7 55.6 3.9 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 0.0 0.8 0.0 0.0 0.0 0.8 0.1 2.9 2.7 2.6 2.8 1.9 3.2 3.5 5.8 3.6 2.1 3.7 1.9 5.0 22.4 20.6 8.8 2.7 18.4 7.1 3.9 23.3 0.8 3.6 3.0 3.3 5.7 4.4 1.8 0.0 0.2 0.4 0.6 0.0 3.6 0.2 1.4 0.6 7.0 0.0 4.8 6.5 1.4 1.3 9.4 6.6 5.0 1.3 9.8 16.8 0.9 1.0 0.0 7.2 1.4 0.0 0.3 7.5 0.5 11.5 2.8 19.6 5.6 0.7 14.7 1.0 4.5 5.2 4.5 0.1 3.4 0.4 4.0 0.5 1.2 0.3 1.2 0.0 0.5 2.7 0.3 1.1 7.6 11.4 0.4 3.6 0.1 1.1 2.7 MEI1 "MGC40042, SPATA38" ENSG00000167077 "Meiotic double-stranded break formation protein 1" Q5TIA1 22 41699503-41799456 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.4;testis: 39.5" "Cell type enhanced" "Detected in many" "B-cells: 32.8;Early spermatids: 61.3;Late spermatids: 50.8;NK-cells: 29.9;Plasma cells: 94.7;Spermatocytes: 38.1;T-cells: 28.4" "Cancer enhanced" "Detected in many" "cervical cancer: 5.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HeLa: 11.6;HMC-1: 8.5;Karpas-707: 26.8;U-266/70: 29.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 7 "olfactory bulb: 1.4" HPA049240 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA049240: AB_2680689" "unprognostic (1.95e-3)" "prognostic favorable (1.59e-6)" "unprognostic (6.13e-3)" "unprognostic (1.86e-2)" "unprognostic (9.70e-2)" "unprognostic (2.97e-3)" "unprognostic (9.04e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" "unprognostic (5.96e-2)" "unprognostic (9.65e-2)" "unprognostic (2.62e-1)" "unprognostic (2.45e-10)" "unprognostic (2.82e-1)" "unprognostic (3.02e-1)" "unprognostic (1.85e-1)" "unprognostic (7.39e-2)" 1.3 1.0 2.3 6.7 4.0 12.1 3.0 2.1 2.9 1.5 1.7 6.4 2.6 0.7 0.3 1.6 1.8 1.3 1.0 2.1 2.2 2.8 1.4 4.5 6.6 2.5 3.5 0.8 0.6 0.1 0.9 0.8 2.3 1.5 3.0 1.3 7.0 0.5 0.5 1.2 8.5 0.8 2.1 22.4 4.4 39.5 4.9 2.5 2.3 0.1 8.1 2.7 1.3 2.6 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 2.3 0.0 0.3 0.6 0.2 0.5 0.5 0.2 0.2 0.2 0.0 0.0 0.0 6.7 0.0 2.0 11.6 1.3 1.8 1.4 8.5 0.1 0.1 0.0 0.0 0.3 0.5 0.8 0.4 26.8 0.1 0.0 0.0 6.5 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 3.7 1.0 0.5 0.0 0.0 0.1 29.9 5.1 1.2 0.4 2.8 0.1 18.5 7.2 15.7 29.9 5.6 29.1 21.7 30.1 25.8 6.5 15.4 21.7 24.0 1.3 16.9 2.3 2.3 57.2 18.1 2.3 4.0 2.1 2.9 2.1 2.2 2.5 3.5 2.3 2.1 4.9 2.6 0.7 0.0 3.2 0.0 32.8 0.9 0.3 0.3 0.0 0.6 0.3 0.3 0.9 0.0 0.1 0.0 0.0 0.1 19.9 0.0 0.0 0.1 61.3 0.3 1.0 1.4 0.0 0.4 2.1 0.0 0.2 2.0 2.0 0.1 14.0 0.5 3.3 0.5 7.0 0.0 1.1 2.9 0.0 1.2 3.5 50.8 0.6 11.1 17.8 3.7 15.5 0.1 29.9 1.0 1.1 5.3 0.0 1.2 94.7 0.3 0.1 0.4 0.1 1.1 0.0 0.7 1.7 38.1 26.1 0.0 1.0 0.0 28.4 0.1 0.4 0.3 MEI4 ENSG00000269964 "Meiotic double-stranded break formation protein 4" A8MW99 6 77650274-77927028 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 4.0;testis: 3.7;thyroid gland: 2.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 86.1" "Cancer enhanced" "Detected in some" "renal cancer: 0.9;testis cancer: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 43: Testis - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.47e-1)" "unprognostic (9.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.31e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (1.88e-1)" "unprognostic (4.62e-2)" "unprognostic (9.70e-4)" "unprognostic (3.16e-1)" "unprognostic (2.86e-4)" "unprognostic (3.35e-2)" "unprognostic (4.17e-2)" "unprognostic (4.85e-2)" 0.1 0.7 0.4 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.2 0.6 4.0 0.8 0.0 0.0 1.0 0.5 0.0 2.0 0.1 1.0 0.0 1.2 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 3.7 0.6 0.0 2.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.2 0.2 0.6 1.0 0.5 1.2 0.5 0.6 0.6 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 86.1 0.0 0.0 0.1 0.0 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 21.3 0.3 0.0 0.0 9.4 0.0 0.6 0.0 2.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MEIS1 ENSG00000143995 "Meis homeobox 1" O00470 2 66433452-66573869 "Disease related genes, Predicted intracellular proteins, Transcription factors" Transcription "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.5;Endometrial stromal cells: 117.2;Horizontal cells: 82.4;Oligodendrocytes: 227.5;Rod photoreceptor cells: 121.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.6;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 43.5;HeLa: 29.3;HHSteC: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011521, HPA056000, HPA058641" Approved Supported Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 51: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "CAB011521: AB_776272, HPA056000: AB_2683004, HPA058641: AB_2683784" "unprognostic (6.84e-2)" "unprognostic (1.08e-1)" "unprognostic (3.43e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-1)" "prognostic favorable (2.70e-5)" "unprognostic (2.45e-2)" "unprognostic (7.78e-3)" "unprognostic (2.36e-2)" "unprognostic (5.91e-2)" "unprognostic (1.07e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (6.52e-2)" "unprognostic (9.71e-2)" "unprognostic (4.13e-2)" "unprognostic (2.01e-2)" 21.8 52.0 7.0 12.0 10.4 2.5 13.1 33.1 8.7 89.8 4.0 72.2 5.7 84.0 23.0 23.0 82.7 15.7 13.8 4.1 8.0 9.5 3.8 34.1 2.3 14.0 10.5 43.6 45.0 6.9 1.6 15.3 18.1 33.8 12.2 43.0 39.0 35.4 5.6 11.7 19.7 50.0 11.3 18.4 31.7 2.9 8.8 4.7 5.8 3.4 6.9 39.2 55.9 19.4 0.3 1.6 12.4 2.7 16.3 10.9 1.6 17.0 43.5 14.4 15.2 1.5 12.3 0.0 4.2 13.5 0.8 2.0 7.7 7.5 14.1 0.0 6.9 20.3 29.3 3.1 31.3 0.0 5.8 9.6 8.8 6.0 2.4 11.5 6.7 3.3 1.8 0.0 0.6 0.7 1.8 0.4 0.3 1.6 1.8 0.0 3.3 3.6 1.2 4.0 3.8 26.2 3.0 1.0 1.3 9.4 1.3 2.5 2.1 3.1 4.8 2.3 4.8 3.4 1.1 0.1 2.3 18.2 0.8 0.8 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.5 1.6 0.0 1.3 0.1 2.1 7.0 10.4 33.1 8.7 4.1 8.0 14.0 10.5 18.1 11.3 8.8 19.4 0.6 0.0 0.5 55.5 0.2 3.2 11.9 10.1 15.4 19.8 2.5 1.4 18.7 1.5 8.3 0.0 110.5 5.7 0.4 2.1 0.0 21.6 10.3 36.8 117.2 4.4 1.2 5.9 6.5 17.5 1.6 19.4 7.1 27.9 0.0 0.2 16.1 1.8 2.2 82.4 5.8 0.7 10.2 1.4 1.9 14.1 34.5 10.3 3.6 15.9 0.5 21.4 1.0 54.3 227.5 20.1 67.3 28.2 0.0 2.4 0.6 3.2 6.8 121.0 19.7 6.7 12.5 2.7 2.0 17.9 2.3 1.9 2.0 6.3 1.2 18.8 MEIS3 "DKFZp547H236, MRG2" ENSG00000105419 "Meis homeobox 3" Q99687 19 47403124-47419527 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.3;endometrium 1: 77.3" "Cell type enhanced" "Detected in many" "Early spermatids: 22.4;Endometrial stromal cells: 23.5;Excitatory neurons: 39.1;Horizontal cells: 45.4;Late spermatids: 57.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 76.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046699 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA046699: AB_2616456" "unprognostic (3.27e-3)" "unprognostic (2.98e-1)" "unprognostic (2.13e-2)" "unprognostic (4.49e-1)" "unprognostic (3.16e-1)" "unprognostic (4.67e-2)" "unprognostic (2.12e-2)" "unprognostic (5.93e-3)" "unprognostic (1.21e-1)" "unprognostic (2.73e-2)" "unprognostic (1.58e-2)" "unprognostic (9.76e-2)" "prognostic unfavorable (1.78e-6)" "unprognostic (9.29e-3)" "unprognostic (9.21e-3)" "unprognostic (4.36e-2)" "unprognostic (3.80e-3)" 13.1 6.9 68.8 9.0 64.3 0.0 16.3 20.5 102.3 41.7 15.7 18.7 6.6 77.3 2.3 10.8 51.8 11.2 10.2 69.2 50.4 7.5 2.0 8.1 2.9 19.8 22.4 21.8 4.2 6.6 17.2 13.7 21.6 18.9 3.9 8.0 6.9 10.9 2.5 6.0 14.1 38.9 16.3 6.7 6.3 12.2 36.4 1.2 6.2 2.7 1.6 17.1 15.7 46.8 1.0 33.4 76.3 0.3 42.0 36.4 1.3 33.1 53.8 27.5 47.5 3.0 5.3 0.3 3.8 58.2 22.6 3.8 8.1 9.6 8.8 50.4 11.3 0.0 12.7 0.3 26.4 0.6 65.0 26.5 1.9 10.5 5.6 9.5 0.0 0.0 0.8 7.7 3.0 32.2 0.0 0.4 22.1 1.0 1.9 0.1 5.8 0.8 1.8 2.4 3.1 59.9 29.3 2.6 14.4 30.5 1.8 9.8 0.0 20.2 49.3 15.1 4.7 0.1 0.0 0.1 56.3 3.2 41.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.8 64.3 20.5 102.3 69.2 50.4 19.8 22.4 21.6 16.3 36.4 46.8 1.7 0.0 3.2 2.3 0.0 0.8 1.2 0.6 0.0 10.0 8.7 4.6 1.4 0.0 1.9 3.7 6.2 0.2 0.1 0.0 0.0 0.1 22.4 0.7 23.5 0.9 0.0 0.0 39.1 0.0 0.4 11.1 0.5 1.6 0.0 0.3 1.4 0.1 0.7 45.4 11.2 0.0 0.0 0.0 1.9 57.4 11.5 0.4 7.2 4.7 0.0 17.0 0.0 13.0 2.0 0.1 0.0 4.1 0.3 4.0 0.0 0.0 1.5 2.9 13.1 0.9 11.8 3.1 4.8 0.1 1.0 0.8 1.2 0.9 0.0 0.9 MELTF "CD228, FLJ38863, MAP97, MFI2, MGC4856, MTf, MTF1" ENSG00000163975 Melanotransferrin P08582 3 196988621-197029817 "CD markers, Plasma proteins, Predicted intracellular proteins" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 35.1;salivary gland: 68.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 21.1;Breast myoepithelial cells: 20.6;Collecting duct cells: 14.7;Ductal cells: 28.3;Hofbauer cells: 15.4;Pancreatic endocrine cells: 66.4" "Cancer enhanced" "Detected in all" "melanoma: 32.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 162.1;SK-MEL-30: 201.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA004880 Approved "Intracellular and membrane" NA NA 41000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA004880: AB_1853844" "unprognostic (8.68e-3)" "unprognostic (3.68e-2)" "unprognostic (1.75e-2)" "unprognostic (7.68e-3)" "unprognostic (1.06e-2)" "unprognostic (1.08e-2)" "unprognostic (5.53e-2)" "unprognostic (1.64e-3)" "unprognostic (1.20e-2)" "unprognostic (1.23e-1)" "unprognostic (3.68e-3)" "unprognostic (8.14e-2)" "prognostic unfavorable (6.99e-11)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "unprognostic (5.75e-2)" "unprognostic (2.09e-2)" 10.0 1.7 2.3 3.8 1.7 2.3 7.4 2.1 3.8 8.1 27.2 4.0 2.4 6.8 0.7 2.9 8.6 1.6 7.5 2.5 1.9 35.1 1.6 1.9 1.9 0.6 2.8 1.2 4.6 10.3 2.9 1.5 0.4 4.1 2.1 0.3 68.7 5.5 1.1 16.4 9.9 1.2 0.5 1.1 1.7 3.4 6.5 2.9 3.1 1.0 1.6 3.2 7.3 2.0 162.1 34.6 0.4 1.2 4.8 6.0 4.0 2.8 1.5 5.2 6.3 9.8 23.6 4.5 33.3 5.6 4.5 49.6 1.8 0.1 2.3 7.4 10.8 5.6 7.9 4.1 30.5 0.8 30.8 33.0 4.3 4.3 0.4 0.2 0.8 8.9 4.3 30.5 3.1 9.8 9.3 0.0 3.6 6.9 22.5 13.4 5.3 2.0 0.8 1.5 3.1 11.3 32.5 2.8 201.4 3.8 9.5 4.8 1.2 1.2 26.8 5.5 19.9 5.3 46.0 4.5 3.9 9.5 0.2 0.0 0.1 0.0 0.2 0.2 0.8 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.2 2.3 1.7 2.1 3.8 2.5 1.9 0.6 2.8 0.4 0.5 6.5 2.0 0.8 0.0 1.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 21.1 20.6 0.0 0.0 1.8 14.7 0.0 0.2 1.0 0.0 0.0 28.3 0.0 3.2 6.1 0.6 0.0 0.0 0.0 5.7 0.3 3.7 0.0 4.4 0.0 3.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 2.6 0.0 0.0 0.0 0.0 66.4 0.0 0.0 1.7 0.0 0.0 0.5 1.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.0 MEPE ENSG00000152595 "Matrix extracellular phosphoglycoprotein" Q9NQ76 4 87821411-87846817 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 107 "brain: 10.6" "Cell type enriched" "Detected in single" 18 "Inhibitory neurons: 12.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 10.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038003, HPA038004" Uncertain "Secreted to extracellular matrix" NA NA 810000 "Cluster 10: Brain - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA038003: AB_2675780, HPA038004: AB_10670537" "unprognostic (2.88e-1)" "unprognostic (8.15e-2)" "unprognostic (3.62e-1)" "unprognostic (1.91e-1)" "unprognostic (1.61e-1)" "unprognostic (4.76e-2)" "unprognostic (1.11e-1)" "unprognostic (3.14e-2)" "unprognostic (1.98e-1)" "unprognostic (2.41e-1)" "unprognostic (5.64e-4)" 0.0 0.0 4.6 0.0 1.1 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 4.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 1.1 0.0 10.6 0.9 4.0 0.3 0.0 0.9 0.2 0.1 2.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 MESD "BOCA, KIAA0081, MESDC2" ENSG00000117899 "Mesoderm development LRP chaperone" Q14696 15 80946289-80989828 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" Chaperone "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 341.4;Extravillous trophoblasts: 279.3;Syncytiotrophoblasts: 436.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039414, HPA041721" Approved Supported "Nuclear bodies,Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 1600000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "Nuclear bodies, Cytosol" "HPA039414: AB_10674981, HPA041721: AB_2756310" "unprognostic (9.21e-2)" "unprognostic (4.50e-2)" "unprognostic (8.02e-2)" "prognostic favorable (2.31e-4)" "unprognostic (4.93e-3)" "unprognostic (2.32e-3)" "unprognostic (3.47e-2)" "unprognostic (3.09e-3)" "unprognostic (4.04e-1)" "prognostic favorable (1.12e-4)" "unprognostic (7.93e-2)" "unprognostic (3.05e-2)" "unprognostic (3.42e-2)" "unprognostic (1.68e-1)" "unprognostic (4.32e-2)" "unprognostic (3.83e-1)" "unprognostic (1.88e-1)" 14.4 17.4 11.9 13.7 13.6 5.4 13.9 13.7 13.0 17.8 14.6 14.6 12.8 11.3 42.7 14.6 12.4 11.5 12.8 11.7 14.2 14.4 20.6 14.1 14.0 13.4 13.1 17.4 19.2 14.0 17.8 26.9 13.8 18.2 14.5 10.4 18.4 14.3 7.7 10.9 12.7 11.1 13.4 13.8 15.3 9.8 13.8 14.2 33.7 10.6 13.2 15.4 14.4 15.0 26.8 40.2 34.6 22.3 57.1 32.4 54.0 40.0 47.4 42.7 51.6 36.0 72.9 22.4 45.4 32.3 45.1 43.8 54.1 41.1 40.3 50.2 35.5 28.3 33.0 61.9 43.7 33.8 30.0 33.9 46.6 36.1 42.4 35.7 41.1 27.0 34.7 55.5 36.7 34.0 20.9 28.3 41.9 39.3 16.4 31.7 21.3 59.7 35.6 36.3 29.9 17.6 43.9 29.3 70.0 62.4 34.0 26.8 32.4 40.9 39.1 22.1 52.2 35.0 48.0 30.2 38.5 59.7 43.8 39.4 26.1 19.1 35.6 24.9 41.8 34.5 37.2 35.4 27.2 35.4 34.6 34.7 8.1 44.8 22.5 45.2 42.5 31.1 11.9 13.6 13.7 13.0 11.7 14.2 13.4 13.1 13.8 13.4 13.8 15.0 59.7 80.1 59.6 0.0 20.6 0.0 0.0 0.0 0.0 0.0 51.0 44.2 0.0 0.0 27.9 58.8 0.0 341.4 41.6 0.0 13.7 100.9 0.0 41.4 79.4 36.9 0.0 0.0 0.0 111.9 279.3 48.4 0.0 69.8 36.6 56.4 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.0 0.0 0.0 86.3 0.0 0.0 0.0 0.0 82.5 0.0 0.0 18.8 0.0 0.0 48.8 43.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.0 436.0 25.8 63.6 0.0 0.0 MEST PEG1 ENSG00000106484 "Mesoderm specific transcript" Q5EB52 7 130486171-130506465 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 771.8" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 833.5;Syncytiotrophoblasts: 999.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 24.2" "Group enriched" "Detected in all" 4 "dendritic cells: 9.1;granulocytes: 19.4;T-cells: 24.2" "Cell line enriched" "Detected in many" 6 "AN3-CA: 12338.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005623 Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "HPA005623: AB_1079364" "unprognostic (6.14e-2)" "unprognostic (5.06e-3)" "unprognostic (9.82e-2)" "unprognostic (1.64e-3)" "unprognostic (3.02e-1)" "unprognostic (1.88e-1)" "unprognostic (9.36e-3)" "unprognostic (1.12e-1)" "unprognostic (7.81e-2)" "unprognostic (6.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (6.20e-5)" "unprognostic (7.09e-2)" "unprognostic (1.05e-1)" "unprognostic (2.30e-1)" "unprognostic (1.67e-2)" 117.5 56.2 30.7 16.1 31.3 12.6 63.1 0.0 27.5 6.1 24.1 27.4 28.7 24.4 6.6 6.8 12.0 23.4 7.5 30.2 73.5 17.8 51.8 43.4 5.5 10.2 19.3 18.8 30.0 8.0 33.2 771.8 14.0 12.7 20.9 39.2 21.4 5.5 6.9 4.6 21.6 17.8 2.5 90.2 8.8 26.3 68.4 10.3 11.8 5.2 4.8 11.0 3.9 9.8 77.9 41.7 197.1 12338.6 3.9 1.2 1.1 84.7 38.5 85.1 40.3 237.2 114.4 37.7 27.1 2.6 74.7 11.0 2.9 1.1 33.3 0.4 0.5 66.8 57.0 39.9 322.2 3.2 0.5 5.9 3.1 64.3 0.1 427.5 32.3 0.1 76.5 0.3 164.9 107.6 7.8 85.0 124.1 113.3 20.0 0.8 2168.8 24.5 92.0 72.0 693.2 2.0 71.9 234.0 1.0 195.6 9.2 57.3 33.6 29.2 0.7 276.1 5.6 3.4 8.6 0.7 103.3 1.2 9.7 19.4 2.6 9.1 0.9 2.9 2.2 3.9 2.5 1.8 9.1 3.4 9.4 24.2 1.5 4.3 1.7 0.4 0.1 6.7 30.7 31.3 0.0 27.5 30.2 73.5 10.2 19.3 14.0 2.5 68.4 9.8 7.4 6.4 6.2 12.7 3.3 4.5 47.3 8.6 9.1 13.5 33.3 36.1 0.9 20.0 5.7 16.5 4.2 833.5 2.1 9.3 11.7 20.3 62.7 8.2 12.7 6.0 29.5 35.9 40.8 40.0 187.8 200.3 3.1 9.5 0.0 6.3 44.6 20.4 92.7 1.7 28.1 19.4 6.1 8.8 3.2 37.5 84.8 6.6 1.8 11.2 1.3 45.3 0.0 18.1 1.8 22.8 27.5 13.5 2.3 27.1 24.6 12.3 2.9 22.0 19.7 205.6 12.0 35.7 36.7 10.0 0.6 999.6 2.1 124.8 31.5 23.4 MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672196-116798377 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 103.6;Club cells: 99.8;Glandular and luminal cells: 161.4;Pancreatic endocrine cells: 93.9;Prostatic glandular cells: 149.3;Urothelial cells: 128.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "cerebral cortex: 7.5;hippocampal formation: 6.6;midbrain: 2.5;pons: 4.9;white matter: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 203.8;CAPAN-2: 219.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005282, CAB018577, HPA055607" Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 179000000 100000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860" "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" 10.3 0.8 0.1 3.4 0.6 7.4 8.9 0.1 7.5 13.1 9.6 9.7 6.5 6.4 2.5 6.1 4.7 11.9 6.2 6.6 0.8 20.1 42.9 20.3 2.3 1.1 2.5 0.8 6.6 0.8 3.8 26.4 4.9 6.7 9.3 3.9 8.7 11.2 14.3 7.7 8.2 5.7 0.3 6.0 15.4 0.5 0.5 3.7 17.6 11.0 3.2 18.4 4.4 7.8 203.8 115.3 0.1 0.6 8.6 8.7 7.9 113.7 48.2 60.3 51.1 25.0 219.0 8.4 179.0 72.1 163.3 51.8 19.7 110.0 123.7 0.3 23.4 0.1 112.5 21.4 1.5 0.3 0.2 11.4 42.4 40.6 129.1 109.4 42.4 0.2 4.5 0.8 114.1 5.0 0.1 0.1 17.3 32.9 113.0 0.2 95.3 0.2 105.8 24.0 16.5 0.0 45.4 15.4 44.9 19.8 0.4 0.9 72.3 89.7 30.6 46.7 88.9 2.5 19.1 1.5 99.3 0.3 12.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 7.5 6.6 0.8 1.1 2.5 4.9 0.3 0.5 7.8 32.6 28.9 103.6 0.3 1.0 39.0 70.5 58.1 38.1 6.7 6.5 6.9 12.3 11.5 99.8 31.3 0.0 76.0 0.4 20.5 0.0 38.5 0.0 52.5 11.6 20.1 7.2 0.0 2.6 46.9 7.5 7.4 32.6 161.4 0.0 0.0 3.9 30.5 7.0 0.0 1.0 20.5 18.3 1.3 2.2 0.1 0.6 4.4 3.6 1.9 1.0 7.6 0.0 0.5 7.7 93.9 5.5 0.0 0.4 149.3 11.2 15.6 34.5 0.3 0.0 37.8 5.2 0.0 0.6 7.9 17.8 21.8 1.2 0.0 16.4 128.6 METRN "C16orf23, MGC2601" ENSG00000103260 "Meteorin, glial cell differentiation regulator" Q9UJH8 16 715118-719655 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 299.3;choroid plexus: 238.6" "Cell type enriched" "Detected in many" 5 "Muller glia cells: 1153.9" "Cancer enhanced" "Detected in all" "glioma: 69.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "MCF7: 178.2;PC-3: 133.1;SK-MEL-30: 93.5" "Region enhanced" "Detected in all" "cerebellum: 612.9" HPA051164 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Secreted in brain" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 5: Muller glia cells - Visual perception" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA051164: AB_2681369" "unprognostic (1.60e-2)" "unprognostic (3.49e-1)" "unprognostic (4.47e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (7.49e-2)" "unprognostic (1.82e-1)" "unprognostic (2.59e-1)" "unprognostic (8.13e-2)" "unprognostic (2.35e-1)" "unprognostic (2.12e-2)" "unprognostic (3.32e-1)" "unprognostic (5.03e-3)" "unprognostic (3.62e-2)" "unprognostic (1.26e-1)" "unprognostic (3.09e-1)" "unprognostic (2.17e-2)" 16.1 36.3 238.0 4.0 233.8 1.5 14.1 203.7 299.3 15.5 238.6 30.7 4.1 17.3 3.0 10.4 37.0 2.5 56.8 209.7 210.3 29.2 49.9 16.8 2.1 258.1 239.0 5.2 46.1 5.5 88.0 3.7 208.5 25.4 1.2 3.0 25.2 13.1 23.3 11.9 12.0 2.9 244.4 12.3 22.2 15.3 258.3 2.4 30.6 5.1 1.8 20.5 11.3 237.4 8.9 73.4 14.2 72.4 24.6 13.8 22.9 17.5 8.7 6.9 4.4 11.0 21.5 1.5 39.6 12.4 26.3 32.6 2.1 17.0 1.1 4.7 32.0 2.9 13.3 57.1 15.1 6.5 9.2 33.3 18.3 2.1 4.2 21.3 2.3 20.3 5.3 1.7 5.2 178.2 2.4 22.0 5.2 9.8 133.1 24.3 16.4 24.4 18.4 2.6 22.5 28.5 6.9 18.9 93.5 1.6 28.6 12.6 8.0 19.4 36.8 22.7 15.4 11.0 3.3 1.7 30.3 4.8 46.6 0.0 0.1 0.2 0.8 0.3 0.5 1.2 0.4 0.8 0.0 0.1 0.2 0.5 0.0 0.5 0.3 0.2 1.0 0.1 238.0 233.8 203.7 299.3 209.7 210.3 258.1 239.0 208.5 244.4 258.3 237.4 46.7 0.0 2.2 91.4 8.5 3.8 17.1 3.3 0.0 45.5 79.5 75.8 16.3 48.6 1.8 16.5 14.6 0.6 26.7 29.0 50.9 8.4 8.0 230.7 54.8 21.5 27.4 2.7 6.6 5.1 2.1 15.1 5.6 14.4 0.0 2.7 20.0 39.5 6.4 70.7 5.7 10.7 2.0 7.8 6.5 25.8 11.1 6.6 10.6 8.4 1.1 1153.9 23.7 44.2 57.6 5.3 26.7 9.4 7.9 27.7 6.2 55.6 9.5 37.9 26.3 11.8 26.7 4.6 11.7 1.4 3.0 0.4 12.7 5.2 9.2 16.2 METRNL ENSG00000176845 "Meteorin like, glial cell differentiation regulator" Q641Q3 17 83079609-83095122 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 252.9" "Cell type enhanced" "Detected in many" "dendritic cells: 640.2;Macrophages: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 119.5;U-2197: 162.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023792 Uncertain "Secreted to blood" NA NA 445000 1300000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA023792: AB_2144182" "unprognostic (7.99e-2)" "unprognostic (2.32e-1)" "unprognostic (1.04e-1)" "unprognostic (1.32e-2)" "unprognostic (6.41e-3)" "unprognostic (7.35e-2)" "unprognostic (4.26e-2)" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (1.01e-1)" "unprognostic (8.51e-2)" "unprognostic (3.50e-3)" "unprognostic (4.43e-1)" "unprognostic (2.23e-1)" "unprognostic (2.46e-1)" "unprognostic (1.61e-2)" 105.4 24.0 7.8 13.2 6.9 21.9 66.8 6.7 8.9 89.0 33.4 57.0 26.6 33.8 2.1 184.1 39.3 12.2 95.8 7.2 6.8 71.4 19.1 80.3 5.1 9.6 9.7 23.0 24.4 25.1 36.5 14.5 7.8 26.4 4.1 3.4 52.9 3.7 15.3 252.9 50.0 4.3 7.3 41.0 41.1 32.4 15.1 3.2 61.3 1.5 4.7 47.4 103.4 6.7 11.4 0.3 5.4 7.3 5.9 21.8 26.7 11.7 5.1 8.4 9.6 1.4 7.8 0.7 4.6 9.1 6.4 29.8 1.9 0.7 5.6 8.6 4.4 26.8 32.0 3.3 14.1 7.8 49.5 10.5 2.2 36.1 2.4 5.3 4.2 0.0 17.1 0.0 7.2 19.0 0.7 23.9 1.1 16.6 16.6 8.2 11.4 3.9 1.3 4.3 0.5 3.6 16.0 29.5 14.2 5.3 27.3 8.2 10.9 119.5 12.5 162.6 3.6 0.0 0.0 0.4 28.1 3.1 7.5 6.8 3.2 10.5 1.8 6.0 0.1 1.4 0.3 1.3 4.5 0.1 0.0 0.5 5.5 3.2 8.1 1.7 1.8 1.5 7.8 6.9 6.7 8.9 7.2 6.8 9.6 9.7 7.8 7.3 15.1 6.7 39.0 25.6 31.1 6.5 28.0 22.9 19.9 4.7 1.2 3.3 19.7 16.5 40.5 14.3 12.3 49.7 6.2 12.4 640.2 110.2 3.9 11.5 9.5 72.6 27.1 16.8 6.0 3.2 0.7 13.9 5.1 56.1 18.3 103.4 32.9 41.5 25.0 1.0 53.8 1.7 2.1 41.4 6.1 62.2 133.6 1.5 7.8 162.0 16.0 1.9 13.7 90.6 25.7 4.0 0.3 19.7 64.9 3.4 95.8 18.4 53.4 8.3 7.4 22.2 0.0 75.4 35.5 5.9 3.4 13.5 49.2 19.2 98.8 0.5 35.1 62.2 METTL14 KIAA1627 ENSG00000145388 "Methyltransferase like 14" Q9HCE5 4 118685392-118715433 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038002 Supported Supported Nucleoplasm Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA038002: AB_10672401" "unprognostic (4.48e-1)" "unprognostic (5.13e-2)" "unprognostic (5.98e-3)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.83e-1)" "unprognostic (3.75e-2)" "unprognostic (4.40e-1)" "unprognostic (9.97e-2)" "unprognostic (2.40e-2)" "unprognostic (3.64e-2)" "unprognostic (3.33e-3)" "prognostic favorable (1.46e-5)" "unprognostic (1.05e-1)" "unprognostic (1.32e-1)" "unprognostic (1.76e-3)" "unprognostic (7.76e-3)" 8.9 8.8 5.2 8.6 6.0 19.5 11.5 6.8 6.3 8.8 5.5 8.8 8.8 11.7 10.7 8.9 8.8 7.7 8.3 4.8 6.3 10.2 14.9 9.1 11.6 5.5 5.2 12.7 7.8 10.9 8.2 9.0 6.3 9.7 8.2 11.7 7.6 8.0 8.4 10.9 9.2 9.2 5.4 10.8 7.9 15.1 5.7 12.5 10.6 7.7 11.0 8.5 7.9 7.4 19.6 8.9 19.0 17.8 11.7 14.7 13.8 17.1 13.0 12.6 14.4 12.9 22.8 22.0 9.8 12.0 12.6 9.4 16.2 14.1 16.1 17.5 9.8 18.5 11.4 14.4 13.3 30.2 21.2 13.1 15.8 14.6 9.6 16.5 11.5 17.4 20.1 18.2 17.5 13.2 29.7 24.7 16.2 16.7 7.7 16.8 23.7 11.2 13.8 12.7 15.4 17.3 12.0 22.0 17.2 17.2 10.0 28.5 15.8 18.1 16.6 16.3 13.7 15.2 17.0 24.9 12.9 16.5 15.1 37.7 12.8 29.0 17.0 19.6 19.3 24.3 17.8 17.7 15.3 25.3 21.0 19.0 10.3 21.8 23.7 12.1 20.8 13.7 5.2 6.0 6.8 6.3 4.8 6.3 5.5 5.2 6.3 5.4 5.7 7.4 18.6 25.6 25.9 14.7 20.6 10.8 18.3 10.6 16.5 16.8 13.4 12.6 15.7 17.2 20.8 23.9 22.9 18.7 28.3 13.7 11.7 11.9 96.9 14.5 21.7 17.3 12.1 8.4 18.7 15.6 10.2 16.8 9.2 18.0 22.1 18.3 16.4 32.1 12.1 8.4 17.0 15.2 6.1 17.9 7.6 16.7 18.6 13.3 7.2 14.0 14.0 13.4 25.7 14.1 26.9 14.8 13.0 13.9 8.2 17.1 15.4 20.6 15.2 25.4 13.1 15.3 15.5 42.2 28.1 12.4 11.9 15.3 20.6 17.0 12.8 16.0 METTL24 "C6orf186, dJ71D21.2" ENSG00000053328 "Methyltransferase like 24" Q5JXM2 6 110245928-110358272 "Predicted secreted proteins" "Methyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "smooth muscle: 14.2" "Group enriched" "Detected in some" 4 "Astrocytes: 30.0;Excitatory neurons: 23.8;Inhibitory neurons: 28.7;Late spermatids: 8.6;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 29 "T-cells: 3.5" "Cell line enhanced" "Detected in some" "HHSteC: 1.0;SCLC-21H: 1.6;SuSa: 1.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037441, HPA037442" Uncertain "Secreted - unknown location" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA037441: AB_10670933, HPA037442: AB_10696931" "unprognostic (6.62e-2)" "unprognostic (1.15e-1)" "unprognostic (9.31e-3)" "unprognostic (5.02e-2)" "unprognostic (5.21e-3)" "unprognostic (1.46e-1)" "unprognostic (6.12e-2)" "unprognostic (2.06e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (8.45e-2)" "unprognostic (5.96e-2)" "unprognostic (1.54e-4)" "unprognostic (4.08e-2)" "unprognostic (1.23e-2)" "unprognostic (1.63e-2)" "unprognostic (4.78e-3)" 1.8 1.6 1.4 1.6 2.3 0.0 1.7 2.1 1.9 3.9 8.1 5.9 1.4 7.5 2.2 4.0 6.0 5.8 3.0 1.7 1.8 3.9 0.9 1.6 0.1 1.6 2.2 5.6 1.3 2.5 2.1 0.4 1.4 4.9 4.2 1.4 0.4 7.1 0.0 0.5 2.1 14.2 2.0 0.7 2.4 2.1 1.8 1.0 1.3 1.1 0.6 4.7 1.6 1.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.3 2.1 1.9 1.7 1.8 1.6 2.2 1.4 2.0 1.8 1.2 0.0 0.0 0.0 30.0 0.3 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.9 0.4 1.5 0.1 0.0 0.0 23.8 0.0 0.0 0.8 0.0 0.4 0.0 0.5 0.0 0.0 0.0 1.7 28.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 3.7 0.0 0.6 0.0 31.7 5.4 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.3 2.1 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 METTL9 DREV1 ENSG00000197006 "Methyltransferase like 9" Q9H1A3 16 21597218-21657473 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 414.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053588, HPA056347" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cell Junctions" Cytosol "HPA053588: AB_2682203, HPA056347: " "unprognostic (1.55e-1)" "unprognostic (2.18e-2)" "unprognostic (1.98e-3)" "unprognostic (5.43e-2)" "unprognostic (5.81e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (8.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.11e-2)" "unprognostic (7.57e-3)" "unprognostic (1.73e-2)" "unprognostic (3.18e-1)" "unprognostic (1.49e-3)" "unprognostic (2.14e-1)" "unprognostic (3.28e-1)" "unprognostic (5.17e-2)" "unprognostic (1.65e-1)" 63.6 100.6 41.9 31.1 52.7 118.7 54.5 39.5 53.2 62.9 53.1 45.2 28.3 46.3 70.5 67.8 42.4 32.9 42.0 44.9 41.7 140.8 16.5 49.2 36.1 44.7 43.4 48.6 39.7 68.1 44.7 36.8 40.3 45.6 31.1 38.6 49.8 28.0 77.4 51.5 39.2 33.1 47.1 54.7 44.3 11.0 46.5 56.9 52.7 52.9 44.1 49.5 57.5 48.2 50.8 41.8 95.3 77.0 99.5 156.2 36.1 85.7 103.8 58.8 68.5 30.4 79.9 92.4 64.8 132.6 53.3 33.0 61.1 71.4 71.2 70.5 72.0 41.1 34.1 120.6 75.1 35.8 81.0 111.6 76.6 54.3 81.1 119.4 111.4 97.8 61.8 57.6 112.3 60.2 93.7 71.2 87.6 60.8 64.0 124.8 80.8 82.7 116.3 44.5 61.8 116.0 66.1 53.1 195.0 65.6 44.5 16.7 75.0 96.9 43.9 62.2 49.5 72.8 102.8 71.4 107.6 80.8 66.3 111.0 75.7 33.4 11.4 14.3 13.5 18.3 19.0 21.1 42.5 20.6 20.4 16.2 36.1 17.0 12.0 14.3 20.4 28.8 41.9 52.7 39.5 53.2 44.9 41.7 44.7 43.4 40.3 47.1 46.5 48.2 82.4 19.2 26.1 32.3 66.9 71.8 89.5 143.8 51.2 52.6 77.7 61.7 53.6 34.3 81.3 86.5 45.9 79.4 94.3 49.6 281.8 119.5 7.8 56.4 68.9 89.2 84.9 146.9 48.2 122.9 124.2 67.6 42.8 64.7 47.7 70.0 98.6 11.2 95.8 45.4 37.8 80.4 101.7 181.7 103.3 6.3 63.3 124.2 104.9 40.3 270.1 92.9 109.2 34.2 28.3 114.9 51.5 65.1 58.0 149.4 81.1 414.2 50.4 43.7 65.7 48.9 108.8 17.1 25.1 74.7 77.0 139.1 111.4 57.4 80.5 142.9 MEX3C "FLJ38871, RKHD2, RNF194" ENSG00000176624 "Mex-3 RNA binding family member C" Q5U5Q3 18 51174550-51218333 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 118.4" "Group enriched" "Detected in many" 6 "Early spermatids: 555.3;Late spermatids: 514.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040603 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA040603: AB_10805714" "unprognostic (1.09e-1)" "unprognostic (2.90e-2)" "unprognostic (8.88e-2)" "unprognostic (8.88e-3)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "prognostic unfavorable (8.49e-5)" "unprognostic (4.34e-2)" "unprognostic (4.43e-1)" "unprognostic (1.05e-2)" "unprognostic (1.03e-2)" "unprognostic (6.75e-2)" "unprognostic (7.99e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-1)" "unprognostic (8.01e-2)" "unprognostic (3.17e-1)" 17.6 13.5 9.1 17.0 9.9 49.4 17.4 12.5 12.3 16.4 9.0 13.5 12.6 17.6 10.4 15.5 14.0 18.6 10.8 10.5 9.8 11.9 14.0 13.7 23.6 10.5 10.0 23.5 14.7 17.9 1.7 16.1 10.6 11.5 14.1 14.8 9.6 12.2 9.7 9.2 13.4 20.1 10.7 22.3 13.3 118.4 9.3 40.9 16.1 17.1 26.6 20.2 2.4 11.6 23.8 19.6 71.2 26.8 27.7 36.8 49.6 32.8 37.4 18.9 22.2 33.6 17.3 53.0 13.2 44.2 30.4 44.6 27.9 42.7 31.0 43.0 12.5 10.7 19.1 29.0 44.5 75.2 22.3 28.2 46.5 26.9 76.4 47.0 41.8 36.0 11.3 95.7 40.0 18.0 63.8 24.3 32.1 13.3 15.0 61.7 36.5 46.7 31.1 9.5 34.8 39.1 30.4 12.4 117.7 54.3 13.5 34.3 43.2 46.3 30.9 15.1 28.1 64.5 12.4 87.2 32.9 31.3 110.7 9.7 1.2 1.5 2.3 1.0 2.0 1.9 2.4 2.4 1.4 1.1 0.9 2.3 0.4 3.4 0.7 1.1 2.0 1.4 9.1 9.9 12.5 12.3 10.5 9.8 10.5 10.0 10.6 10.7 9.3 11.6 25.2 19.2 5.0 6.8 18.6 38.2 10.3 12.4 11.4 12.6 25.9 23.2 14.5 14.3 11.2 3.7 20.9 5.2 56.6 9.0 5.9 12.1 555.3 18.9 22.7 30.0 6.7 7.4 8.0 8.5 7.0 18.2 6.1 34.9 12.7 79.3 10.4 7.6 7.7 11.8 7.9 9.4 12.2 10.9 20.5 514.0 16.1 13.8 19.6 5.6 8.2 10.0 34.0 14.1 13.3 16.5 3.9 15.1 20.6 15.4 9.1 9.3 6.4 14.8 0.0 30.2 17.7 14.4 14.2 18.1 45.9 4.2 24.2 14.9 11.5 19.6 MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 197.8;Fibroblasts: 75.8;Granulosa cells: 93.3;Leydig cells: 53.7;Peritubular cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 249.4;ASC TERT1: 249.6;HUVEC TERT2: 263.1;SH-SY5Y: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" NA NA 210000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA007354: AB_1079365" "unprognostic (5.10e-2)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.92e-2)" "unprognostic (4.86e-1)" "unprognostic (1.53e-3)" "unprognostic (3.72e-3)" "unprognostic (2.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.98e-1)" "unprognostic (9.45e-3)" "unprognostic (9.12e-2)" "prognostic unfavorable (2.52e-8)" "unprognostic (2.18e-3)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-3)" 36.6 4.2 0.4 13.3 0.6 0.1 22.7 0.5 1.1 81.8 1.6 15.0 5.0 61.4 22.1 6.1 19.0 73.2 13.8 0.5 0.6 9.4 1.6 20.1 4.2 0.7 0.9 35.8 18.8 4.5 13.2 42.4 0.7 22.1 4.8 4.9 16.5 12.1 2.6 27.6 12.1 30.6 0.5 2.7 8.3 11.2 0.7 1.6 9.5 3.0 2.3 22.5 36.7 0.6 0.0 0.2 93.2 0.3 249.4 249.6 6.2 26.3 102.5 39.7 73.7 24.1 1.1 0.0 82.6 89.7 0.1 0.1 7.2 7.7 15.9 0.1 78.0 0.0 37.1 2.1 23.4 0.1 0.1 104.4 18.8 109.4 42.7 113.1 263.1 0.0 0.2 16.2 19.2 12.5 0.1 0.1 108.8 0.5 0.8 1.5 0.0 4.0 0.9 0.3 5.0 212.1 9.0 36.6 9.6 71.1 11.9 13.0 75.6 65.6 128.4 51.7 2.8 0.1 0.3 0.2 53.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.5 1.1 0.5 0.6 0.7 0.9 0.7 0.5 0.7 0.6 5.5 0.0 1.7 0.0 0.1 6.6 7.8 28.7 8.0 0.2 2.1 3.9 0.9 2.8 10.7 3.7 0.0 4.5 0.0 0.1 0.0 1.3 12.9 5.6 28.7 7.1 10.1 0.0 0.0 0.8 197.8 75.8 2.0 8.3 0.0 93.3 1.4 0.0 7.4 0.0 0.0 0.4 12.2 0.0 7.7 7.6 53.7 0.6 17.8 2.8 0.0 27.7 0.0 0.0 0.0 1.9 0.0 63.9 0.5 1.5 0.0 0.0 1.9 0.8 0.0 3.3 14.7 3.2 8.7 0.6 6.3 29.0 0.9 0.5 0.2 1.2 MFAP3 ENSG00000037749 "Microfibril associated protein 3" P55082 5 154038959-154220478 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 24.3;Inhibitory neurons: 24.5;Microglial cells: 17.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015883, HPA049198" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoplasm "HPA015883: AB_1853840, HPA049198: AB_2680672" "unprognostic (6.02e-2)" "prognostic unfavorable (4.28e-4)" "unprognostic (1.58e-3)" "unprognostic (2.40e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (6.58e-3)" "unprognostic (1.21e-1)" "unprognostic (3.07e-2)" "unprognostic (1.53e-2)" "unprognostic (7.00e-2)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (2.05e-1)" "unprognostic (7.16e-3)" "unprognostic (9.35e-3)" 16.0 8.5 5.4 13.2 5.4 12.1 12.5 8.1 7.0 13.2 10.1 10.8 9.5 12.0 9.8 14.7 9.7 11.8 14.1 5.3 6.3 13.5 13.7 11.3 10.6 5.8 6.2 9.4 7.1 24.4 3.1 19.6 6.3 9.4 10.8 12.2 7.2 9.0 10.4 7.6 9.6 16.6 6.5 11.4 9.6 5.7 5.7 11.8 13.4 17.1 13.0 16.1 6.5 6.0 14.9 19.7 36.5 37.7 29.8 24.7 31.5 26.4 28.0 27.0 37.1 27.4 34.1 25.0 30.6 26.3 25.8 33.5 32.5 35.6 41.9 9.5 21.0 15.7 26.5 12.9 29.5 27.7 16.0 29.2 32.4 35.0 29.1 22.6 38.4 19.9 17.5 20.5 21.4 11.0 15.2 9.9 20.0 16.0 9.9 14.6 40.7 20.8 20.8 21.0 32.1 40.3 27.4 35.0 31.1 30.1 34.6 14.8 32.9 34.3 26.4 19.4 26.9 25.7 33.5 21.4 18.7 19.2 27.4 6.7 7.5 11.9 5.0 7.9 6.9 2.4 4.0 3.5 8.1 2.5 5.2 4.1 6.8 6.5 5.6 3.7 3.9 4.3 5.4 5.4 8.1 7.0 5.3 6.3 5.8 6.2 6.3 6.5 5.7 6.0 9.7 0.0 0.5 14.0 3.5 6.0 1.0 6.1 6.2 3.2 1.6 1.5 2.7 0.0 3.9 5.5 6.2 4.3 2.7 1.9 1.9 1.4 7.1 1.4 4.3 7.6 0.0 9.1 24.3 1.1 3.0 3.9 4.1 2.2 4.5 2.1 1.4 1.9 1.9 3.3 24.5 1.2 8.2 0.6 4.4 4.9 1.8 2.7 8.8 17.8 0.7 6.9 1.0 12.1 15.1 1.1 0.3 0.0 9.5 1.3 2.1 1.1 4.6 4.6 0.0 1.5 3.3 3.9 2.0 4.3 5.5 6.0 4.0 1.2 1.0 1.5 MFAP3L "KIAA0626, NYD-sp9" ENSG00000198948 "Microfibril associated protein 3 like" O75121 4 169986597-170033031 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.5;choroid plexus: 88.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1840.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 5.7;eosinophil: 1.8;neutrophil: 3.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.7" "Cell line enhanced" "Detected in many" "HMC-1: 22.5;RT4: 38.0;SK-BR-3: 34.3;SuSa: 19.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017986, HPA062306, HPA077490" Enhanced Supported "Nucleoplasm,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Cell Junctions" "HPA017986: AB_1853842, HPA062306: , HPA077490: AB_2686842" "unprognostic (8.04e-3)" "unprognostic (8.67e-3)" "unprognostic (3.74e-1)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (7.92e-2)" "unprognostic (3.50e-2)" "unprognostic (3.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.33e-1)" "unprognostic (3.96e-1)" "unprognostic (7.58e-2)" "prognostic favorable (1.42e-8)" "unprognostic (6.59e-3)" "unprognostic (2.12e-1)" "unprognostic (1.62e-4)" "unprognostic (2.40e-3)" 2.0 3.4 32.9 0.9 61.0 3.2 12.0 49.1 34.4 13.0 88.8 2.7 0.6 5.1 38.9 0.8 4.2 2.6 1.7 35.2 40.1 30.0 37.4 2.7 0.9 46.3 58.3 0.6 1.5 6.5 4.1 3.0 48.5 2.8 2.0 25.0 2.1 12.8 5.1 24.5 1.0 4.1 38.8 1.5 1.3 46.3 54.9 0.6 2.8 2.3 0.5 10.1 1.8 65.5 0.4 5.7 3.0 3.1 2.6 1.3 1.1 6.2 0.9 2.8 2.5 1.9 0.4 0.0 0.2 9.6 5.4 2.9 10.9 1.4 1.2 0.0 4.7 0.0 6.7 2.4 1.4 0.0 22.5 1.8 3.4 0.3 1.0 1.5 0.3 3.5 0.9 1.1 5.8 3.4 1.0 0.8 3.1 0.7 4.7 0.0 1.8 0.0 8.1 38.0 2.5 5.5 5.1 34.3 11.6 19.1 1.9 0.0 0.2 2.9 11.2 5.5 11.9 0.6 0.0 0.0 7.5 1.2 11.4 5.7 0.1 1.8 0.6 0.7 0.3 0.0 0.5 0.1 0.2 0.0 0.2 0.1 3.5 0.0 0.0 0.5 0.1 4.6 32.9 61.0 49.1 34.4 35.2 40.1 46.3 58.3 48.5 38.8 54.9 65.5 1.0 0.0 5.6 112.6 0.6 2.5 0.4 0.1 2.8 12.2 8.5 9.7 3.4 0.0 0.2 36.8 20.9 3.1 0.2 0.6 5.9 0.5 417.5 8.5 1.1 2.0 2.4 11.2 36.3 1.1 1.0 0.6 0.0 12.4 4.5 11.0 3.3 49.1 1.2 3.3 25.0 0.3 0.0 1.0 0.7 1840.0 5.3 13.5 7.2 3.7 1.5 2.9 2.1 53.8 127.6 1.4 0.3 9.1 0.5 0.9 0.3 24.0 0.3 15.8 19.7 1.7 4.2 17.6 13.2 0.3 8.4 9.4 0.6 1.4 0.8 2.2 MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Fibroblasts: 903.5;Peritubular cells: 240.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 394.8;ASC TERT1: 597.9;fHDF/TERT166: 284.0;HHSteC: 275.4;HSkMC: 417.8;MOLT-4: 375.8;SH-SY5Y: 350.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" 271.8 81.9 6.5 74.0 10.0 2.7 197.7 7.0 9.5 326.1 13.1 287.5 102.0 237.3 289.0 293.2 227.5 646.2 273.2 6.1 8.3 61.4 45.6 634.7 65.7 7.7 9.0 325.8 71.3 7.0 87.5 156.7 6.6 226.7 139.1 17.3 108.1 129.8 41.6 144.7 187.6 262.7 6.9 59.8 176.1 31.8 8.1 42.4 114.5 249.7 78.6 488.8 244.6 6.9 0.3 0.7 0.6 0.1 394.8 597.9 0.8 44.8 160.0 4.6 3.2 0.2 0.0 0.2 0.1 284.0 0.1 0.2 0.1 0.0 0.8 0.3 1.2 0.0 0.3 0.0 275.4 14.4 0.2 417.8 0.0 2.6 0.1 4.7 0.0 3.9 0.1 0.0 0.4 0.0 375.8 33.8 7.1 0.1 0.4 26.4 24.9 0.7 0.0 0.2 35.8 350.2 0.4 0.2 0.3 2.4 0.4 82.4 0.2 50.9 3.3 2.3 0.1 0.4 0.5 0.1 48.9 15.4 0.1 0.0 0.1 1.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 6.5 10.0 7.0 9.5 6.1 8.3 7.7 9.0 6.6 6.9 8.1 6.9 35.1 3.2 12.1 0.0 0.3 47.5 0.7 0.2 5.7 0.7 2.3 4.2 10.7 0.0 3.1 1.8 0.0 7.2 1.3 0.0 0.0 0.2 0.7 0.3 21.4 15.9 0.0 0.0 0.0 0.0 3.6 903.5 6.1 0.4 1.3 0.1 15.4 0.2 9.4 0.0 0.0 0.0 0.0 0.0 62.9 6.3 78.3 3.9 67.6 14.0 0.0 80.2 0.0 0.5 0.1 0.1 0.0 240.0 2.6 2.2 0.0 0.0 2.9 3.3 19.7 38.6 103.1 0.4 0.5 8.8 41.1 19.4 6.9 0.2 0.0 2.2 MFAP5 "MAGP2, MP25" ENSG00000197614 "Microfibril associated protein 5" Q13361 12 8637346-8662888 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 242.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 140.5;Extravillous trophoblasts: 1015.1;Fibroblasts: 579.7;Syncytiotrophoblasts: 252.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 31.7" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 172.2;BJ: 63.7;EFO-21: 150.4;HeLa: 55.9;SuSa: 137.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 42.6" HPA010553 Enhanced "Secreted to extracellular matrix" NA NA 3200000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA010553: AB_1853843" "unprognostic (1.80e-1)" "unprognostic (1.11e-2)" "unprognostic (4.25e-2)" "unprognostic (4.84e-2)" "unprognostic (1.44e-1)" "unprognostic (6.05e-2)" "unprognostic (2.15e-3)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (8.79e-2)" "unprognostic (8.63e-3)" "unprognostic (3.05e-1)" "unprognostic (4.41e-7)" "prognostic unfavorable (6.87e-4)" "unprognostic (8.81e-2)" "unprognostic (2.05e-2)" "prognostic unfavorable (5.81e-4)" 141.7 10.9 3.5 5.4 5.0 3.5 79.7 31.7 9.2 59.9 1.8 37.8 7.2 242.1 11.1 35.0 25.8 28.2 54.4 4.8 0.8 3.1 12.7 8.7 4.8 2.9 0.4 2.4 5.5 2.4 3.7 94.5 1.9 6.4 42.0 7.9 17.2 49.7 28.5 38.7 19.0 142.1 0.0 1.9 23.6 6.9 1.7 3.2 14.4 118.1 3.4 43.1 60.7 6.6 1.4 5.7 1.6 2.6 29.4 12.4 172.2 63.7 1.2 0.8 1.1 2.3 1.0 0.6 150.4 19.8 1.6 9.1 0.6 13.1 0.0 0.5 0.4 1.6 55.9 1.9 0.4 1.3 0.6 8.7 4.4 7.3 0.0 3.3 0.0 2.0 2.7 3.7 52.7 0.8 1.9 0.8 3.2 0.9 2.9 1.2 1.3 6.5 6.5 2.6 0.7 0.9 1.9 0.7 1.0 137.1 24.0 0.8 2.3 10.7 21.5 45.7 3.0 2.1 1.9 2.3 6.0 0.7 0.1 2.9 0.8 0.7 0.2 0.7 0.4 0.1 0.1 0.1 0.4 0.3 0.4 0.1 1.1 0.2 0.5 0.3 0.0 0.3 3.5 5.0 31.7 9.2 4.8 0.8 2.9 0.4 1.9 0.0 1.7 6.6 61.5 12.8 5.8 0.3 0.5 23.1 0.4 1.8 0.6 0.2 0.6 0.9 7.0 0.0 2.0 0.0 0.0 140.5 0.5 0.0 0.0 0.5 0.3 5.1 3.9 20.1 0.0 0.0 0.2 0.0 1015.1 579.7 3.6 28.0 0.0 0.2 4.2 0.0 27.7 0.0 0.1 0.0 0.0 9.5 36.3 0.5 61.2 8.8 12.4 0.0 0.1 0.1 0.0 0.0 0.1 0.8 0.0 0.0 1.6 0.1 0.0 0.2 1.6 0.9 0.0 40.2 35.2 0.1 0.2 0.6 18.0 252.3 5.3 0.1 0.0 0.3 MFGE8 "BA46, EDIL1, hP47, HsT19888, MFG-E8, OAcGD3S, SED1, SPAG10" ENSG00000140545 "Milk fat globule EGF and factor V/VIII domain containing" Q08431 15 88898683-88913381 "Cancer-related genes, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 407.0;Cone photoreceptor cells: 385.7;Rod photoreceptor cells: 978.7;Sertoli cells: 1084.7;Smooth muscle cells: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.9" "Group enriched" "Detected in many" 8 "granulocytes: 5.3;NK-cells: 7.7;T-cells: 14.9" "Cell line enhanced" "Detected in many" "ASC diff: 1784.6;ASC TERT1: 918.2;fHDF/TERT166: 660.4;HSkMC: 935.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002753, HPA002807" Enhanced Approved Cytosol "Secreted to blood" NA NA 2830000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "CAB002753: , HPA002807: AB_1078072" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.63e-2)" "unprognostic (7.68e-2)" "unprognostic (2.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (8.11e-3)" "unprognostic (6.27e-2)" "unprognostic (8.49e-2)" "unprognostic (3.99e-1)" "prognostic unfavorable (6.06e-9)" "prognostic unfavorable (3.08e-4)" "unprognostic (4.85e-2)" "unprognostic (7.36e-3)" "unprognostic (2.41e-3)" 237.2 95.2 44.2 45.2 49.6 3.7 226.7 56.4 61.8 272.8 52.4 113.7 21.2 444.7 77.0 67.6 361.8 120.2 485.8 41.6 47.2 69.0 15.6 137.2 47.4 55.9 47.4 228.5 36.5 18.9 49.3 79.6 55.6 129.3 29.3 68.7 97.1 195.8 264.3 118.9 106.9 162.7 47.0 40.7 124.9 38.3 46.5 18.8 90.6 124.1 36.9 163.6 223.4 55.6 19.7 85.4 78.7 98.7 1784.6 918.2 6.9 482.7 142.4 95.4 110.3 90.5 23.5 0.0 147.5 660.4 144.6 10.2 27.6 95.8 31.1 82.3 64.7 138.1 4.6 10.2 469.8 0.2 50.1 935.7 251.8 73.5 122.5 205.3 37.0 35.3 23.4 41.1 185.1 6.2 22.6 3.2 405.4 8.3 38.4 22.7 74.4 26.4 32.6 7.3 8.2 42.9 28.0 2.5 226.1 165.6 2.4 11.1 42.0 233.2 127.8 62.3 36.3 145.3 30.5 15.9 31.6 12.2 91.5 5.3 0.2 0.4 1.3 0.0 4.2 1.2 4.2 2.9 0.0 0.9 4.3 3.3 0.0 7.7 0.1 0.1 14.9 2.1 44.2 49.6 56.4 61.8 41.6 47.2 55.9 47.4 55.6 47.0 46.5 55.6 72.1 12.8 5.4 39.2 4.0 48.7 32.2 116.3 24.5 22.1 407.0 190.4 92.8 8.6 25.5 3.7 385.7 4.5 13.1 1.6 0.0 15.7 11.0 33.3 202.2 66.9 44.8 3.8 5.1 4.3 18.6 220.0 12.8 29.7 5.1 30.1 22.1 15.5 8.1 16.8 0.4 6.4 36.7 32.9 39.7 27.9 187.0 12.9 119.2 15.0 1.8 75.9 9.2 5.5 9.6 28.3 0.2 109.1 8.8 15.8 0.1 0.2 8.3 978.7 1084.7 51.8 476.0 3.3 9.0 21.7 35.9 5.3 12.5 25.8 2.0 10.2 MFNG ENSG00000100060 "MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" O00587 22 37469063-37486393 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 69.1" "Cell type enhanced" "Detected in many" "Adipocytes: 51.4;dendritic cells: 54.6;Endothelial cells: 37.1;Hepatic stellate cells: 53.2;Kupffer cells: 45.8;monocytes: 40.6;NK-cells: 72.1;T-cells: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 174.6;HEL: 143.4;HL-60: 220.9;HMC-1: 266.9;HUVEC TERT2: 232.9;TIME: 134.7;U-698: 166.8;U-937: 201.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048936, HPA056479" Approved Approved Vesicles "Intracellular and membrane" NA NA 74000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA048936: AB_2680564, HPA056479: " "unprognostic (1.21e-1)" "unprognostic (4.17e-3)" "prognostic unfavorable (5.12e-4)" "prognostic favorable (1.65e-4)" "unprognostic (6.41e-3)" "unprognostic (1.00e-2)" "unprognostic (2.64e-1)" "unprognostic (2.36e-2)" "unprognostic (4.64e-2)" "unprognostic (2.91e-2)" "unprognostic (5.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (2.67e-1)" "unprognostic (4.03e-2)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" 22.2 7.1 8.9 37.0 8.9 40.3 14.8 8.4 10.8 8.9 6.4 10.5 8.6 9.7 2.4 7.5 11.0 14.5 14.6 7.9 9.2 9.5 7.1 26.3 69.1 18.1 10.8 3.1 3.9 2.6 3.1 30.3 20.5 6.6 7.8 0.7 5.4 5.7 7.5 5.0 24.0 11.5 10.2 58.9 8.6 2.9 11.0 50.5 9.6 8.8 42.5 13.9 6.2 10.3 6.0 2.2 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 7.1 3.0 174.6 0.7 0.0 0.8 10.8 45.1 8.7 0.2 81.6 1.0 143.4 0.6 1.5 0.6 220.9 266.9 0.0 2.6 1.7 3.2 0.9 232.9 69.0 0.7 73.8 0.0 1.5 27.8 3.0 0.4 6.1 1.0 67.0 1.8 128.7 0.4 0.1 94.1 0.9 0.5 0.3 0.3 0.8 1.3 14.1 134.7 0.0 5.8 22.8 0.6 0.4 0.4 166.8 1.1 201.1 2.7 210.3 198.9 386.5 196.1 196.1 214.5 103.0 222.7 206.1 204.1 113.5 243.4 209.9 127.9 217.1 218.7 51.7 284.3 314.0 8.9 8.9 8.4 10.8 7.9 9.2 18.1 10.8 20.5 10.2 11.0 10.3 51.4 0.0 3.8 0.0 35.4 3.7 0.4 0.2 0.0 6.3 1.0 1.3 1.6 5.7 3.1 0.0 0.0 0.3 54.6 1.1 0.0 2.9 0.2 0.4 0.2 37.1 1.2 30.1 0.1 0.9 0.3 1.1 2.0 1.0 31.6 0.1 53.2 1.5 31.9 0.0 0.1 2.1 0.0 45.8 20.2 0.3 0.0 33.5 3.6 6.5 40.6 0.1 72.1 0.0 0.0 3.7 4.0 0.0 35.0 0.5 2.3 0.3 0.1 0.6 0.0 1.6 1.0 0.1 0.7 0.3 2.4 0.7 51.0 0.1 0.8 0.4 MFSD4A "DKFZp761N1114, FLJ25004, FLJ34577, MFSD4, UNQ3064" ENSG00000174514 "Major facilitator superfamily domain containing 4A" Q8N468 1 205568885-205602918 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 66.7;stomach 1: 132.6" "Cell type enhanced" "Detected in some" "Adipocytes: 11.3;Collecting duct cells: 9.2;Distal tubular cells: 13.7;Endometrial ciliated cells: 9.9;Glandular and luminal cells: 40.5;Proximal tubular cells: 7.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 17 "amygdala: 11.4;basal ganglia: 8.4;cerebral cortex: 18.4;hippocampal formation: 14.1;white matter: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 59.8" HPA055407 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA055407: " "unprognostic (7.15e-4)" "prognostic favorable (7.54e-4)" "unprognostic (5.60e-2)" "unprognostic (1.38e-1)" "unprognostic (2.09e-1)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic favorable (4.59e-4)" "unprognostic (2.73e-2)" "unprognostic (1.65e-2)" "unprognostic (3.20e-2)" "unprognostic (6.97e-3)" "prognostic favorable (2.27e-13)" "unprognostic (1.58e-1)" "unprognostic (4.44e-2)" "unprognostic (5.75e-3)" "unprognostic (8.78e-2)" 2.2 0.4 11.4 1.1 8.4 0.0 2.7 0.6 18.4 8.5 0.0 13.8 1.9 1.0 9.2 1.4 2.5 16.8 0.9 14.1 0.0 66.7 0.2 6.8 0.4 0.0 0.0 0.6 1.4 0.4 1.5 6.2 0.0 1.4 18.2 14.0 17.1 0.6 0.3 5.1 1.4 0.8 0.0 0.6 132.6 0.5 0.0 0.6 0.4 0.7 1.3 0.7 0.8 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 8.4 0.6 18.4 14.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 11.3 6.4 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 3.8 2.9 0.0 0.0 6.2 9.2 0.0 0.5 0.7 0.0 13.7 1.4 0.0 9.9 6.0 2.5 0.0 0.0 0.0 6.2 0.1 0.5 0.0 40.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 7.7 2.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.8 0.2 0.0 0.0 MFSD4B "KIAA1919, MGC33953" ENSG00000173214 "Major facilitator superfamily domain containing 4B" Q5TF39 6 111259327-111445354 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 30.7;Cytotrophoblasts: 24.5;Glandular and luminal cells: 22.4;granulocytes: 20.2;Granulosa cells: 34.4;Syncytiotrophoblasts: 31.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031784 Approved "Intracellular and membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA031784: AB_10603775" "unprognostic (2.98e-2)" "unprognostic (1.64e-2)" "unprognostic (1.89e-2)" "unprognostic (3.00e-1)" "unprognostic (1.94e-1)" "unprognostic (3.07e-2)" "unprognostic (7.50e-5)" "unprognostic (3.51e-2)" "unprognostic (2.33e-1)" "unprognostic (6.84e-2)" "unprognostic (2.94e-2)" "unprognostic (3.41e-1)" "unprognostic (6.04e-3)" "unprognostic (9.27e-2)" "unprognostic (3.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.98e-4)" 1.3 1.7 1.5 1.8 1.6 2.2 2.1 2.0 1.5 2.3 7.2 1.4 3.6 1.5 2.4 1.3 1.7 1.3 1.1 1.3 1.6 2.9 2.6 1.4 1.6 1.0 0.7 1.1 1.3 1.8 1.6 4.7 0.5 1.3 1.7 3.0 1.7 1.8 2.0 2.5 3.4 1.6 0.1 1.6 1.6 4.3 1.7 1.4 2.0 0.9 1.3 1.5 1.1 0.8 1.5 3.3 2.8 7.1 2.8 1.7 4.4 2.1 3.1 3.2 4.2 5.5 2.7 3.9 3.3 2.7 3.1 3.4 5.5 2.2 5.1 2.6 1.4 5.0 5.4 3.6 3.9 3.9 8.3 1.2 3.8 3.7 3.0 4.2 2.7 4.9 5.5 5.9 3.5 2.7 3.5 2.4 2.2 3.5 0.9 3.9 2.4 1.6 4.1 4.0 2.0 2.5 2.2 2.7 1.3 3.0 2.2 5.4 2.1 3.3 1.8 16.7 4.0 2.0 2.9 3.9 4.5 3.2 4.0 4.4 1.4 1.9 1.7 1.7 2.0 2.1 1.1 1.1 1.5 1.2 1.5 1.7 1.9 1.7 1.6 1.8 0.9 1.0 1.5 1.6 2.0 1.5 1.3 1.6 1.0 0.7 0.5 0.1 1.7 0.8 4.2 9.6 30.7 0.0 3.2 0.0 0.0 0.0 0.0 0.0 3.7 2.2 0.0 0.0 13.6 5.5 0.0 24.5 5.3 0.0 1.9 5.6 0.0 15.0 9.4 4.1 0.0 0.0 0.0 3.6 11.5 4.9 0.0 22.4 20.2 34.4 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 2.6 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.8 0.0 0.0 6.6 10.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 31.1 2.8 5.7 0.0 0.0 MGA "FLJ12634, KIAA0518, MAD5, MXD5" ENSG00000174197 "MAX dimerization protein MGA" Q8IWI9 15 41621224-41773081 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042278, HPA058183" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA042278: AB_10794647, HPA058183: AB_2683632" "unprognostic (5.78e-2)" "unprognostic (7.97e-2)" "unprognostic (2.97e-1)" "unprognostic (7.20e-2)" "unprognostic (6.26e-3)" "unprognostic (5.82e-3)" "unprognostic (8.61e-3)" "unprognostic (1.70e-1)" "unprognostic (1.90e-2)" "unprognostic (3.96e-3)" "unprognostic (3.71e-1)" "unprognostic (3.80e-2)" "unprognostic (1.43e-2)" "unprognostic (1.57e-1)" "unprognostic (3.93e-1)" "unprognostic (2.50e-1)" "unprognostic (3.89e-1)" 3.9 5.2 7.0 5.4 12.1 8.7 7.2 33.6 8.5 7.3 0.0 4.5 3.7 7.4 6.0 4.5 5.8 4.2 4.5 4.9 11.6 5.2 4.6 4.3 7.6 6.4 6.9 12.0 5.0 6.0 3.9 6.9 8.8 5.7 5.1 7.0 5.1 5.5 5.1 6.2 3.9 5.7 3.8 6.8 4.6 8.7 8.6 11.6 7.5 7.8 7.6 5.4 3.9 17.3 2.4 13.5 16.6 10.9 12.8 10.1 13.3 6.7 6.8 7.8 7.7 14.5 7.8 16.2 11.8 7.8 14.2 9.3 25.9 5.9 10.7 7.7 8.5 34.3 22.1 12.8 11.3 31.9 16.4 7.7 7.2 10.9 10.7 3.2 10.3 15.5 40.7 7.2 7.1 6.7 19.4 12.3 10.3 7.0 6.9 21.7 16.9 8.5 4.1 9.8 15.7 15.3 24.0 8.2 4.3 12.1 6.6 20.1 11.0 9.5 13.3 9.8 8.0 9.8 15.7 15.3 6.0 11.9 4.8 3.6 1.4 1.6 2.5 1.0 2.5 2.8 2.1 2.9 1.4 3.0 2.1 2.4 0.6 5.8 3.3 2.4 1.1 1.0 7.0 12.1 33.6 8.5 4.9 11.6 6.4 6.9 8.8 3.8 8.6 17.3 18.5 22.4 19.8 56.5 28.1 7.9 10.9 7.2 13.6 25.5 11.1 8.9 29.5 5.7 16.2 12.9 33.3 18.1 23.6 9.7 7.9 11.8 16.7 16.8 35.4 18.6 7.8 28.6 62.4 5.3 12.0 20.5 18.8 24.9 14.5 32.9 15.0 9.3 11.8 13.5 60.1 10.0 8.2 11.9 8.8 7.0 20.8 17.1 8.8 44.0 13.2 16.0 25.7 64.8 122.6 8.1 13.5 20.7 16.4 16.2 7.6 5.2 14.9 23.6 39.5 35.6 19.2 45.4 40.4 11.7 11.2 26.0 27.5 23.5 11.3 10.7 MGAT1 "GLCNAC-TI, GLYT1, GNT-1, GnTI, MGAT" ENSG00000131446 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase" P26572 5 180784780-180815652 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 280.2;Syncytiotrophoblasts: 384.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017432 Approved NA NA 12000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA017432: AB_1853851" "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (3.38e-2)" "unprognostic (2.11e-1)" "unprognostic (3.91e-2)" "unprognostic (6.70e-2)" "unprognostic (4.39e-2)" "unprognostic (9.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.98e-1)" "unprognostic (3.70e-3)" "unprognostic (6.44e-2)" "prognostic unfavorable (8.65e-4)" "unprognostic (4.15e-2)" "unprognostic (3.52e-2)" "unprognostic (5.68e-2)" "unprognostic (5.00e-2)" 130.4 66.7 44.0 65.8 43.8 60.6 113.7 40.7 59.9 70.7 64.6 69.8 50.2 75.2 28.2 103.2 85.8 39.9 103.2 38.4 42.0 63.3 146.9 113.3 68.5 56.7 43.2 75.1 115.3 20.3 61.7 67.3 54.0 75.5 30.1 29.2 82.0 37.1 61.1 73.4 82.2 40.9 47.4 139.9 78.1 36.4 64.9 38.3 96.1 35.6 42.2 85.0 72.3 49.3 58.3 58.2 30.9 66.3 149.6 68.7 111.0 130.1 154.4 77.4 96.7 79.4 45.6 50.2 77.3 122.3 78.2 68.8 17.0 190.8 46.1 271.6 47.6 44.2 34.1 61.7 72.8 40.6 137.6 79.7 91.5 63.1 62.9 53.6 67.9 34.2 26.1 84.7 70.9 78.3 38.9 55.2 29.6 37.5 72.0 46.2 44.5 66.8 30.9 67.3 27.2 32.1 54.6 56.5 115.7 27.2 43.8 68.5 72.9 94.7 44.7 42.7 61.1 165.9 149.2 44.7 77.6 78.9 49.8 93.0 228.6 104.6 83.5 186.7 91.6 48.3 60.2 70.3 161.7 42.0 51.4 59.1 152.2 70.4 149.4 152.9 75.3 235.1 44.0 43.8 40.7 59.9 38.4 42.0 56.7 43.2 54.0 47.4 64.9 49.3 157.8 48.1 31.1 9.8 57.7 61.2 44.6 52.8 50.1 20.7 41.5 29.7 18.4 44.3 32.7 29.5 56.3 94.9 114.7 43.8 37.2 49.0 31.7 26.2 34.2 94.2 49.8 47.6 7.5 79.0 280.2 80.5 33.6 48.7 30.4 27.2 125.7 88.1 200.5 63.9 8.5 54.9 20.3 195.5 142.1 43.2 62.7 234.9 81.8 26.2 112.1 18.9 87.6 8.0 14.6 54.0 34.7 76.0 169.7 76.9 57.2 22.5 20.4 78.8 32.9 72.1 51.5 26.8 22.5 46.8 63.9 384.9 59.3 43.7 36.7 56.8 MGAT2 GNT-II ENSG00000168282 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase" Q10469 14 49620799-49623481 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043721, HPA056824" Approved Supported "Golgi apparatus" NA Yes 5100000 "Cluster 44: Non-specific - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043721: AB_2678636, HPA056824: AB_2683248" "unprognostic (1.20e-2)" "prognostic unfavorable (3.22e-4)" "unprognostic (2.84e-1)" "unprognostic (5.49e-2)" "unprognostic (1.37e-1)" "unprognostic (1.70e-1)" "unprognostic (3.77e-1)" "unprognostic (1.92e-2)" "unprognostic (1.14e-1)" "unprognostic (7.44e-2)" "unprognostic (7.12e-2)" "unprognostic (5.63e-2)" "unprognostic (2.59e-3)" "unprognostic (9.14e-2)" "unprognostic (3.74e-2)" "unprognostic (4.72e-2)" "unprognostic (2.12e-2)" 16.8 17.6 5.9 24.3 5.8 10.3 13.3 6.9 6.8 17.4 9.0 23.6 23.1 12.7 21.7 11.8 11.9 15.2 11.7 5.6 6.7 14.2 40.7 13.8 25.3 6.4 6.3 13.1 23.8 8.2 7.9 22.0 6.6 14.1 21.9 8.2 15.8 13.7 5.0 9.3 22.5 16.0 6.9 20.2 21.0 24.3 7.2 16.4 13.3 5.6 25.1 20.9 8.8 7.3 63.5 30.7 23.2 39.2 53.6 51.7 15.1 68.6 67.7 62.2 55.8 37.5 47.1 63.7 56.9 62.9 36.0 49.5 32.9 39.7 66.7 65.5 29.1 40.7 21.7 37.2 42.3 94.5 91.2 39.8 31.2 36.8 51.8 45.5 75.5 31.4 31.7 170.4 66.3 24.2 32.9 60.1 23.8 22.2 49.1 36.7 67.1 55.6 49.3 36.2 24.0 25.6 49.3 12.9 39.8 22.2 39.1 63.6 78.9 56.1 60.8 41.1 49.6 182.8 94.6 56.7 27.3 46.5 38.6 49.4 38.6 39.3 36.6 34.1 39.3 25.1 33.3 33.1 39.9 15.9 19.3 26.8 11.6 22.3 39.8 47.2 31.6 44.8 5.9 5.8 6.9 6.8 5.6 6.7 6.4 6.3 6.6 6.9 7.2 7.3 17.4 12.8 8.6 2.0 31.7 15.7 25.7 28.8 14.2 13.7 15.5 8.9 0.1 24.3 18.0 11.0 4.2 26.4 46.9 34.6 9.8 31.0 7.9 12.5 20.7 20.8 12.1 19.0 3.0 34.4 40.3 24.3 13.7 11.7 17.1 27.7 27.1 63.0 37.2 18.5 4.3 20.5 40.7 34.5 28.8 6.0 17.4 26.3 21.4 2.8 40.6 16.7 63.8 6.0 4.5 36.5 25.1 22.2 77.1 27.0 26.7 15.2 23.5 15.8 6.6 15.8 34.6 56.4 13.0 15.2 14.1 5.3 31.5 23.2 20.0 25.5 MGAT3 GNT-III ENSG00000128268 "Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase" Q09327 22 39457012-39492194 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.0;intestine: 28.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 44.8;Bipolar cells: 30.7;Excitatory neurons: 25.1;Inhibitory neurons: 27.4;Oligodendrocytes: 45.7;Proximal enterocytes: 37.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4;eosinophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 65.1;HMC-1: 56.0;OE19: 58.8;U-266/70: 73.6;U-266/84: 32.6;U-698: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017598 Approved "Intracellular and membrane" NA NA 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA017598: AB_1853853" "unprognostic (1.41e-3)" "unprognostic (5.98e-3)" "unprognostic (4.79e-2)" "unprognostic (2.96e-1)" "unprognostic (2.76e-1)" "unprognostic (5.71e-3)" "unprognostic (8.92e-2)" "unprognostic (2.17e-1)" "unprognostic (4.35e-3)" "unprognostic (6.77e-2)" "unprognostic (8.12e-3)" "unprognostic (8.74e-2)" "prognostic unfavorable (5.04e-8)" "unprognostic (6.73e-2)" "unprognostic (1.46e-1)" "unprognostic (5.89e-2)" "unprognostic (4.92e-2)" 7.8 1.1 26.8 4.0 20.9 10.8 6.4 7.6 47.0 6.2 0.0 5.2 21.5 3.8 0.8 1.1 3.4 3.8 4.8 30.3 10.0 3.0 0.2 14.9 7.6 28.1 15.6 1.2 3.1 0.4 1.8 10.5 21.8 1.2 4.6 6.7 1.8 1.0 1.5 2.3 28.4 2.8 4.8 4.8 7.4 5.4 23.9 1.8 1.5 1.8 9.0 1.6 1.5 27.3 0.3 0.4 10.4 1.0 0.0 0.0 65.1 0.5 0.7 0.5 0.0 14.9 3.7 23.4 8.1 0.0 0.2 1.3 5.4 0.0 0.1 0.0 0.5 18.9 0.0 0.2 0.2 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 15.8 2.9 0.0 0.2 0.6 1.4 3.1 58.8 0.0 1.2 0.0 3.9 0.4 0.6 6.0 4.4 0.0 0.0 0.0 18.5 0.8 1.0 0.0 0.1 8.1 0.1 0.1 73.6 32.6 32.6 0.2 0.1 1.7 1.4 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 26.8 20.9 7.6 47.0 30.3 10.0 28.1 15.6 21.8 4.8 23.9 27.3 2.0 44.8 3.0 6.5 2.2 0.4 0.1 1.8 0.0 30.7 0.6 1.1 1.9 1.5 3.7 0.0 6.2 5.5 0.0 4.1 0.0 0.0 19.1 0.9 11.0 2.5 7.8 13.7 25.1 0.2 12.0 2.3 10.2 2.0 2.5 0.0 0.0 0.0 1.5 13.5 27.4 3.8 2.0 0.0 2.3 16.6 4.4 0.9 0.0 0.0 0.1 1.5 0.0 21.6 45.7 1.8 6.1 3.8 1.7 0.3 37.4 1.8 5.2 2.3 6.6 0.3 4.3 0.7 1.2 0.2 0.6 3.7 0.5 0.6 4.5 1.5 MGAT4A "GnT-4a, GnT-Iva" ENSG00000071073 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A" Q9UM21 2 98619106-98731132 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.0" "Cell type enhanced" "Detected in many" "Microglial cells: 175.2;Proximal enterocytes: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 127.2;HUVEC TERT2: 48.3;JURKAT: 86.5;TIME: 78.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007608 Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "HPA007608: AB_10602008" "prognostic unfavorable (4.30e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.48e-8)" "unprognostic (1.35e-1)" "unprognostic (2.28e-2)" "unprognostic (3.82e-3)" "unprognostic (1.89e-1)" "unprognostic (3.76e-1)" "unprognostic (3.58e-1)" "unprognostic (2.80e-2)" "unprognostic (2.32e-2)" "unprognostic (4.17e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-2)" "unprognostic (4.04e-2)" "unprognostic (2.04e-1)" 11.2 7.8 13.2 20.8 17.8 96.0 12.5 26.1 15.6 8.9 15.1 24.4 29.5 5.8 3.7 6.3 7.0 12.7 7.6 13.1 15.2 27.5 9.7 16.9 21.1 16.4 15.8 3.2 38.8 28.0 9.8 19.6 15.5 7.5 25.5 5.4 25.9 6.4 3.8 4.1 43.8 11.5 18.1 8.1 11.3 6.3 15.5 20.5 8.7 4.7 18.2 13.1 4.7 22.9 8.8 1.7 3.4 7.3 0.0 0.0 127.2 0.0 0.1 0.9 0.0 21.0 10.6 0.0 18.9 0.0 2.4 0.4 7.2 1.0 0.2 10.6 7.9 0.5 0.0 36.7 0.2 17.8 6.4 0.0 4.7 0.0 0.7 0.3 48.3 86.5 1.6 9.2 0.0 17.3 39.3 30.9 1.1 7.6 1.4 9.8 0.0 10.5 24.8 17.6 10.4 3.3 2.5 32.2 4.8 9.2 7.6 23.8 78.8 0.0 4.0 0.1 2.6 3.2 7.6 2.2 0.0 26.7 0.6 7.0 5.1 12.7 20.8 1.0 27.5 3.6 25.2 23.7 3.8 2.5 32.6 27.2 14.0 15.3 2.5 17.1 16.0 12.5 13.2 17.8 26.1 15.6 13.1 15.2 16.4 15.8 15.5 18.1 15.5 22.9 80.8 54.5 25.7 19.2 22.7 9.9 21.1 6.1 11.4 19.8 28.2 15.6 13.4 11.5 17.6 22.0 4.2 6.2 116.9 92.4 21.5 20.8 12.7 14.2 3.8 39.8 53.0 6.3 58.0 29.8 77.9 7.2 19.4 35.1 13.3 5.1 18.9 10.4 57.2 48.8 48.6 41.3 34.6 33.9 18.3 17.5 2.5 54.5 10.6 175.2 21.0 13.4 89.6 36.7 42.0 21.6 58.2 2.2 31.4 17.8 132.4 27.3 7.1 4.8 6.6 6.8 4.9 2.5 7.7 8.6 10.5 14.9 112.2 0.7 40.9 30.2 MGAT4B GnT-Ivb ENSG00000161013 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B" Q9UQ53 5 179797597-179806952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 277.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 224.7;Proximal enterocytes: 224.5;Undifferentiated cells: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 5.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012804, HPA052134" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" NA NA 19000 "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "HPA012804: , HPA052134: AB_2681741" "unprognostic (2.01e-2)" "unprognostic (8.68e-3)" "unprognostic (1.40e-1)" "unprognostic (3.83e-2)" "prognostic unfavorable (6.15e-5)" "unprognostic (3.61e-3)" "unprognostic (7.57e-3)" "unprognostic (1.22e-2)" "unprognostic (2.02e-1)" "unprognostic (5.13e-2)" "unprognostic (2.26e-2)" "unprognostic (2.27e-2)" "prognostic favorable (5.78e-4)" "unprognostic (1.52e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.42e-1)" 48.4 105.0 17.2 19.0 16.9 24.6 39.9 16.8 19.3 37.0 18.1 147.0 134.1 36.9 13.4 75.1 37.2 23.5 103.3 18.9 14.2 124.8 277.1 61.2 15.5 16.3 15.0 41.1 63.3 22.9 37.7 17.9 15.1 42.3 65.0 4.4 57.9 11.9 43.8 53.4 168.3 14.9 14.6 52.8 96.3 30.6 18.0 10.5 60.1 14.9 16.0 38.7 42.1 16.2 84.2 85.3 40.8 93.7 117.4 65.1 71.1 48.3 98.3 44.4 34.8 91.7 226.4 14.4 122.3 108.2 193.1 61.6 57.9 110.1 32.2 121.0 33.0 43.5 75.1 78.4 85.9 53.7 13.4 70.5 76.6 44.1 53.0 165.2 89.1 16.9 28.7 38.5 73.6 92.6 8.4 47.4 24.7 123.7 35.1 21.6 31.4 40.4 132.3 158.5 67.5 39.7 73.7 75.2 139.1 33.8 51.3 56.3 109.2 106.6 48.6 61.2 80.2 32.5 39.5 35.4 125.0 68.2 78.7 0.0 0.4 5.5 0.1 0.1 0.0 0.0 0.3 0.1 0.3 0.9 0.2 0.3 0.1 0.0 0.3 0.3 0.0 0.2 17.2 16.9 16.8 19.3 18.9 14.2 16.3 15.0 15.1 14.6 18.0 16.2 35.7 12.8 9.2 9.4 7.7 12.5 17.8 12.5 5.2 15.5 29.6 30.7 24.1 37.1 11.1 27.6 4.2 8.1 22.1 224.7 3.9 66.7 0.7 27.2 17.8 24.3 22.9 5.5 11.4 54.0 11.1 15.3 78.5 50.5 5.1 39.5 26.7 89.9 17.7 30.3 10.0 72.2 14.2 20.7 11.7 2.6 15.2 24.5 10.6 9.4 16.8 25.7 6.2 4.5 6.3 89.9 114.6 17.0 7.0 49.0 224.5 22.4 7.7 11.1 13.1 16.2 24.7 1.5 6.5 21.1 11.9 14.0 12.5 24.9 131.8 64.8 MGAT4D GnT1IP ENSG00000205301 "MGAT4 family member D" A6NG13 4 140442262-140498377 "Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 37 "testis: 22.7" "Group enriched" "Detected in some" 19 "Early spermatids: 19.5;Late spermatids: 26.7;Spermatocytes: 64.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036523 Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA036523: AB_10670110" "unprognostic (2.70e-1)" "unprognostic (3.16e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 26.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MGAT5B "FLJ25132, GnT-IX, GnT-VB" ENSG00000167889 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B" Q3V5L5 17 76868404-76950393 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 12.0" "Cell type enhanced" "Detected in some" "Astrocytes: 16.0;Early spermatids: 7.3;Excitatory neurons: 26.2;Inhibitory neurons: 21.9;Late spermatids: 8.1" "Group enriched" "Detected in many" 5 "glioma: 2.6;melanoma: 7.1;testis cancer: 2.4" "Region enhanced" "Detected in many" "cerebral cortex: 12.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 32.1;SCLC-21H: 15.9;U-138 MG: 19.2;U-2 OS: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011082 Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Mitotic spindle" "Cytokinetic bridge" "HPA011082: AB_2668423" "unprognostic (6.37e-2)" "unprognostic (9.16e-3)" "unprognostic (8.51e-2)" "unprognostic (1.43e-3)" "unprognostic (5.68e-3)" "unprognostic (1.33e-1)" "unprognostic (2.28e-3)" "unprognostic (1.52e-3)" "unprognostic (5.30e-2)" "unprognostic (3.89e-2)" "unprognostic (1.68e-1)" "unprognostic (5.67e-2)" "unprognostic (1.46e-7)" "unprognostic (1.66e-1)" "unprognostic (8.09e-3)" "unprognostic (1.04e-1)" "unprognostic (3.01e-1)" 0.2 0.2 2.4 0.2 2.1 0.1 0.1 0.0 12.0 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.0 5.2 0.0 0.2 0.0 0.3 0.1 0.3 0.0 0.2 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.1 1.2 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.0 3.7 32.1 6.4 3.4 0.0 0.0 3.7 0.4 1.3 11.7 6.9 0.1 0.7 0.0 2.5 1.5 13.7 0.2 1.6 0.2 3.0 0.1 0.5 0.0 1.7 0.1 0.0 0.0 0.2 0.1 0.2 0.0 1.8 5.2 2.0 0.7 0.2 0.0 0.0 1.5 0.1 0.0 1.8 0.8 3.5 4.8 5.6 7.1 8.9 0.1 15.9 6.1 5.5 2.4 5.0 0.4 0.2 0.2 5.8 19.2 20.9 0.3 6.3 0.0 0.0 0.7 0.6 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.1 0.0 12.0 5.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 16.0 0.1 0.1 0.1 0.0 0.0 5.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.1 0.1 0.8 0.0 0.0 26.2 0.0 3.2 0.2 0.0 0.2 0.0 0.6 0.7 0.0 0.1 0.0 21.9 0.0 0.0 0.0 0.0 8.1 0.6 0.0 0.0 2.8 0.0 0.2 0.0 5.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.1 1.1 2.4 0.0 0.0 0.1 0.1 0.2 0.0 0.0 MGP ENSG00000111341 "Matrix Gla protein" P08493 12 14880864-14885857 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 9375.3;Breast myoepithelial cells: 4639.0;Fibroblasts: 4233.6;Hepatic stellate cells: 1826.5;Leydig cells: 2016.2" "Cancer enriched" "Detected in all" 5 "breast cancer: 845.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 9 "dendritic cells: 1.6" "Cell line enriched" "Detected in many" 5 "AN3-CA: 9874.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013949 Approved "Secreted to blood" NA NA 29000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 35: Glandular cells - Unknown function" "HPA013949: AB_1853599" "unprognostic (5.71e-3)" "unprognostic (5.85e-3)" "unprognostic (1.20e-3)" "unprognostic (2.83e-2)" "unprognostic (1.27e-1)" "unprognostic (1.21e-1)" "unprognostic (1.55e-2)" "unprognostic (4.17e-3)" "unprognostic (1.01e-2)" "unprognostic (6.93e-2)" "unprognostic (1.90e-1)" "unprognostic (4.26e-2)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.55e-2)" "unprognostic (4.69e-2)" "unprognostic (7.50e-2)" "unprognostic (8.97e-3)" 1737.5 1510.2 50.6 187.4 63.8 1.6 3734.8 48.9 253.3 1738.8 198.1 1827.5 69.8 2043.8 752.9 218.2 2280.1 1083.5 2854.4 49.0 48.2 1316.9 58.1 1269.6 107.0 57.0 49.1 838.7 218.9 109.7 923.0 204.2 51.2 1955.5 277.3 7.5 2112.7 1140.7 177.0 357.6 819.0 1310.0 53.9 142.2 905.9 142.3 58.4 99.5 1500.7 275.0 65.9 987.7 1266.3 48.8 0.9 0.0 0.1 9874.6 1624.2 2.4 3.7 31.8 1.0 0.0 0.0 0.0 12.7 0.2 0.5 3.1 0.4 0.1 0.2 0.2 0.0 0.3 0.3 0.0 1.3 0.0 55.0 0.2 0.2 33.6 0.0 0.0 1.5 3.2 105.4 0.0 0.0 0.3 0.0 0.9 1.2 4.8 7.0 2.2 0.0 0.4 0.2 2.6 0.0 10.5 4.8 31.1 2.0 8.9 0.6 2.8 1810.9 0.1 21.7 11.1 1.2 3.6 28.7 0.5 0.1 1.1 9.0 0.6 8.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 50.6 63.8 48.9 253.3 49.0 48.2 57.0 49.1 51.2 53.9 58.4 48.8 451.0 19.2 72.8 1.3 29.9 149.3 220.4 0.3 19.9 0.5 9375.3 4639.0 70.2 8.6 187.5 115.8 4.2 19.0 85.7 0.1 1.9 2.3 16.9 14.7 355.8 856.1 0.0 18.7 0.2 83.4 13.5 4233.6 86.2 10.9 13.9 0.3 1826.5 6.0 30.8 0.0 0.1 0.0 0.0 9.4 219.9 67.9 2016.2 36.1 225.9 23.4 2.6 28.8 0.0 0.0 0.2 1.8 1.1 1301.8 17.0 164.3 0.0 0.7 25.8 6.8 841.5 558.8 847.0 8.2 6.1 25.8 118.5 39.5 54.5 140.6 0.0 74.6 MGST2 MGST-II ENSG00000085871 "Microsomal glutathione S-transferase 2" Q99735 4 139665768-139740745 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid metabolism" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.2" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 441.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 194.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 276.3;OE19: 558.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010690, HPA010707" Enhanced Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Endoplasmic reticulum" "HPA010690: , HPA010707: AB_1853922" "unprognostic (9.35e-2)" "unprognostic (6.13e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (4.38e-2)" "unprognostic (2.77e-2)" "unprognostic (8.78e-2)" "unprognostic (6.41e-2)" "prognostic favorable (3.22e-9)" "unprognostic (4.10e-1)" "unprognostic (9.91e-2)" "unprognostic (1.77e-2)" "unprognostic (1.01e-2)" 61.8 92.7 43.5 30.4 42.9 42.6 66.6 45.1 60.6 63.6 54.8 112.5 132.5 39.2 82.1 177.6 70.8 87.6 118.3 42.6 45.7 99.2 393.2 49.0 36.0 46.6 44.6 26.3 66.2 102.0 44.6 75.6 46.5 74.9 121.2 7.8 90.6 50.0 104.2 97.1 143.5 57.4 46.6 60.5 72.5 50.6 45.3 35.1 45.8 118.4 64.6 86.7 78.4 48.9 40.8 58.5 28.7 0.3 4.8 15.4 17.7 7.2 66.1 3.2 10.7 62.3 276.3 0.1 158.2 17.5 13.6 74.8 52.7 81.2 4.9 22.3 47.7 174.9 57.3 251.5 13.3 152.7 130.0 53.0 197.2 2.1 12.5 63.9 166.3 0.3 75.9 25.7 23.3 33.9 0.2 24.7 6.5 558.9 59.4 12.7 33.4 54.0 153.0 87.4 71.9 21.6 53.2 83.2 64.8 2.0 52.9 202.2 104.9 5.6 27.3 7.8 6.4 29.7 22.5 9.7 3.8 254.8 12.6 43.8 103.8 30.4 4.1 64.8 2.9 1.3 7.6 3.5 147.0 2.4 2.3 2.6 17.7 26.4 22.2 194.6 37.7 39.4 43.5 42.9 45.1 60.6 42.6 45.7 46.6 44.6 46.5 46.6 45.3 48.9 327.9 25.6 36.6 5.5 7.7 61.1 295.9 316.7 75.7 7.8 99.1 57.3 100.5 205.9 185.5 95.6 25.0 85.3 71.0 168.3 90.1 121.0 6.3 132.5 27.1 238.4 121.8 60.2 19.4 138.6 62.8 31.8 90.2 172.9 43.2 56.9 203.1 419.3 378.1 6.7 24.2 215.1 170.9 107.8 77.8 12.8 44.4 85.3 39.2 49.6 83.6 14.1 27.8 11.6 4.7 121.8 213.1 33.4 7.1 94.6 441.1 277.2 126.6 3.5 13.1 44.6 49.6 4.6 15.1 264.0 124.9 67.2 15.2 43.6 258.2 344.9 MIA CD-RAP ENSG00000261857 "MIA SH3 domain containing" Q16674 19 40771648-40777490 "Cancer-related genes, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 57.9;pituitary gland: 76.2;salivary gland: 43.3;stomach 1: 65.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 51.4;Breast myoepithelial cells: 171.7;Melanocytes: 103.2;monocytes: 30.0;Pancreatic endocrine cells: 66.8;Respiratory ciliated cells: 53.9" "Cancer enriched" "Detected in many" 5 "melanoma: 58.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.7" "Group enriched" "Detected in some" 29 "AN3-CA: 90.1;CAPAN-2: 80.6;SK-MEL-30: 271.9;WM-115: 247.7" HPA042369 Approved "Secreted to blood" NA NA 8270000 64000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 4: Stomach - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA042369: AB_10794420" "prognostic favorable (2.08e-4)" "unprognostic (1.30e-1)" "unprognostic (3.15e-1)" "unprognostic (9.02e-3)" "unprognostic (2.27e-1)" "unprognostic (1.11e-1)" "unprognostic (6.37e-3)" "unprognostic (3.67e-2)" "unprognostic (1.61e-1)" "unprognostic (9.37e-2)" "unprognostic (1.17e-1)" "unprognostic (3.19e-1)" "unprognostic (3.29e-8)" "unprognostic (5.88e-2)" "unprognostic (2.44e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" 2.6 2.9 4.9 6.9 5.9 2.9 57.9 5.7 7.5 8.3 5.4 16.9 2.0 1.2 2.0 6.6 3.7 2.9 5.3 4.4 4.8 2.4 2.7 1.9 2.0 5.3 5.0 7.0 1.4 0.0 76.2 2.1 5.6 6.4 4.2 0.4 43.3 3.3 0.7 9.6 5.9 7.6 4.8 7.0 65.8 1.7 5.5 2.4 2.9 1.7 1.6 4.0 5.2 7.9 0.3 0.9 1.5 90.1 1.3 1.2 1.0 0.0 0.0 0.0 0.5 0.5 80.6 0.2 0.0 0.0 0.3 0.2 0.4 4.9 0.1 2.9 0.9 0.0 1.0 0.1 0.4 0.2 0.4 0.7 4.2 0.0 1.5 1.4 0.0 1.4 0.0 0.9 0.0 0.0 0.1 0.0 0.2 5.9 0.3 0.1 0.2 0.0 2.5 0.0 0.2 0.1 0.1 0.0 271.9 3.4 0.5 1.2 0.0 0.2 3.4 0.1 1.0 0.0 0.2 0.9 0.1 0.4 247.7 0.6 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.0 4.9 5.9 5.7 7.5 4.4 4.8 5.3 5.0 5.6 4.8 5.5 7.9 1.0 0.0 0.5 0.0 0.3 5.2 0.1 11.2 0.6 0.0 51.4 171.7 0.6 0.0 4.9 0.0 0.0 0.8 0.5 1.7 0.0 0.5 0.0 0.9 0.0 1.4 0.0 0.0 0.0 3.2 0.1 1.1 14.3 0.2 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.1 4.1 0.0 0.7 0.3 0.6 0.2 103.2 0.0 30.0 0.0 0.0 0.0 0.0 66.8 5.1 0.0 0.1 0.8 0.4 0.0 53.9 0.0 0.0 0.2 1.3 0.1 0.6 6.1 1.3 0.7 0.3 0.8 4.1 0.5 MIA2 "cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, CTAGE5, FLJ22404, MEA6, MGEA, MGEA11, MGEA6, TALI" ENSG00000150527 "MIA SH3 domain ER export factor 2" Q96PC5 14 39230231-39388513 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 138.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 44.1;Ductal cells: 42.9;Endometrial ciliated cells: 78.7;Exocrine glandular cells: 42.7;Glandular and luminal cells: 93.5;Pancreatic endocrine cells: 41.3;Proximal tubular cells: 61.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 125.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000387, HPA000922, HPA054066, HPA055459" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "HPA000387: AB_1078582, HPA000922: AB_1078581, HPA054066: AB_2682368, HPA055459: AB_2682819" "unprognostic (2.62e-1)" "unprognostic (7.17e-3)" "unprognostic (2.33e-1)" "unprognostic (5.27e-4)" "unprognostic (3.21e-4)" "unprognostic (2.63e-1)" "unprognostic (2.48e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-1)" "unprognostic (1.21e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.93e-2)" "unprognostic (8.08e-2)" "unprognostic (2.91e-1)" "unprognostic (3.97e-2)" 12.1 26.6 5.6 16.8 6.9 23.6 22.1 5.8 7.9 29.7 58.0 30.8 80.4 15.7 40.2 26.9 22.2 30.3 16.6 9.4 6.5 78.4 138.9 15.5 16.2 5.6 4.7 9.6 43.6 40.5 15.5 11.2 6.4 21.1 34.6 12.8 52.5 19.2 54.5 9.9 78.4 12.3 4.1 14.5 45.3 21.0 5.1 14.3 46.7 20.7 19.8 16.2 17.2 7.1 23.0 25.1 10.4 18.5 20.6 23.2 14.5 13.3 13.9 9.3 9.6 19.7 125.4 27.5 40.1 15.0 18.9 34.1 12.7 15.0 11.0 21.4 10.6 17.2 11.5 106.1 48.2 23.2 30.7 14.4 83.7 9.2 69.2 59.0 15.3 31.8 16.6 68.3 14.0 22.1 14.9 18.9 12.0 87.2 20.8 15.2 18.3 34.9 42.7 24.7 8.7 5.1 31.0 32.5 20.4 13.1 31.2 24.8 24.3 14.1 9.2 10.4 8.8 38.7 35.7 27.2 7.9 14.5 12.0 40.9 16.3 25.9 15.4 18.0 14.0 11.7 11.6 14.4 17.8 13.1 14.2 13.2 34.5 14.6 21.0 12.3 11.8 11.8 5.6 6.9 5.8 7.9 9.4 6.5 5.6 4.7 6.4 4.1 5.1 7.1 26.7 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 33.1 19.9 0.0 5.7 0.0 44.1 0.0 5.6 35.9 0.8 7.9 42.9 0.5 78.7 30.7 7.1 0.0 0.0 0.1 42.7 5.0 4.6 0.0 93.5 0.0 10.3 0.0 3.8 7.6 0.0 0.1 1.8 0.0 0.0 0.0 0.6 0.0 12.7 0.0 0.0 23.8 0.0 1.0 0.0 0.0 41.3 0.0 0.0 8.1 0.0 6.6 61.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 7.0 13.6 20.0 0.2 0.0 MICA PERB11.1 ENSG00000204520 "MHC class I polypeptide-related sequence A" 6 31399784-31415315 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 97.7;HSkMC: 65.6;hTERT-RPE1: 52.5;RPTEC TERT1: 44.6" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (1.94e-1)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.01e-1)" "unprognostic (6.55e-2)" "unprognostic (2.66e-2)" "unprognostic (6.10e-2)" "unprognostic (5.19e-2)" "unprognostic (4.09e-2)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (1.13e-1)" "unprognostic (1.77e-1)" "unprognostic (1.23e-1)" "unprognostic (4.92e-2)" "unprognostic (2.18e-1)" "unprognostic (1.12e-2)" 30.8 35.3 1.5 5.2 2.4 6.1 29.3 3.6 5.6 53.4 2.7 36.8 3.7 29.1 10.9 20.3 34.0 10.6 28.9 2.1 2.3 34.5 28.6 43.1 7.2 2.6 2.4 49.9 21.6 2.9 10.7 3.4 2.3 32.1 6.6 2.3 20.0 1.2 10.5 20.5 23.0 4.3 2.0 28.5 23.1 17.3 2.3 2.2 29.5 4.2 2.5 32.4 39.1 4.2 44.5 0.3 2.4 3.5 32.3 41.3 0.7 2.0 1.4 1.4 1.3 2.0 0.1 1.8 25.8 38.3 97.7 26.0 31.1 38.4 4.4 1.7 17.1 0.0 39.4 0.7 11.9 0.0 1.4 65.6 0.1 0.3 0.5 52.5 0.9 5.4 4.5 5.5 2.7 0.4 0.7 6.0 1.4 0.2 0.0 1.3 0.0 4.6 44.6 0.6 0.8 0.1 3.3 0.3 2.2 1.0 0.7 2.2 32.9 1.8 8.7 2.5 1.2 7.0 26.4 3.5 1.3 0.4 2.6 1.0 0.4 1.7 0.6 1.0 0.8 0.5 0.7 0.8 0.8 0.8 0.9 0.7 1.4 0.2 0.3 0.3 1.0 1.0 1.5 2.4 3.6 5.6 2.1 2.3 2.6 2.4 2.3 2.0 2.3 4.2 22.9 32.1 12.2 20.5 8.3 40.0 26.9 54.4 19.4 0.8 12.4 10.7 7.2 12.8 22.3 18.4 0.0 0.2 11.6 26.0 0.0 29.6 1.8 7.1 8.2 22.7 2.4 4.2 3.8 45.4 0.5 24.1 13.3 11.6 9.5 6.7 24.7 9.4 14.6 0.0 1.2 22.0 42.7 14.5 36.8 1.5 14.9 11.6 33.8 19.7 17.7 10.0 17.5 1.5 0.1 51.2 20.1 15.8 8.6 32.7 40.1 7.0 17.1 0.8 19.7 10.7 24.1 15.3 6.6 14.8 34.4 0.8 15.2 11.3 12.2 21.1 MICOS10 "C1orf151, FLJ36999, Mic10, MINOS1, MIO10, RP5-1056L3.2" ENSG00000173436 "Mitochondrial contact site and cristae organizing system subunit 10" Q5TGZ0 1 19484403-19629821 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 453.9;Cytotrophoblasts: 283.4;Extravillous trophoblasts: 279.7;Hofbauer cells: 531.0;Syncytiotrophoblasts: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA059930 Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA059930: AB_2684167" "unprognostic (3.84e-2)" "unprognostic (8.74e-3)" "unprognostic (2.66e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.88e-1)" "unprognostic (8.74e-2)" "unprognostic (3.96e-1)" "unprognostic (1.37e-1)" "unprognostic (2.43e-2)" "unprognostic (1.24e-3)" "unprognostic (7.13e-2)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "prognostic favorable (8.11e-4)" 4.9 5.0 11.5 3.1 11.6 2.6 6.0 11.9 13.6 8.6 11.0 9.3 5.1 7.0 6.2 7.2 7.3 4.1 12.6 11.5 13.1 9.7 4.0 4.6 4.3 12.9 11.7 6.4 5.2 11.1 9.5 4.0 13.1 8.5 8.8 5.9 5.1 8.3 14.3 4.8 6.0 7.0 11.3 3.6 6.7 3.4 13.8 4.0 6.5 16.8 5.9 7.0 6.2 11.1 10.0 13.3 7.3 8.4 13.7 13.6 4.5 8.3 9.6 9.5 10.1 9.3 8.7 8.1 6.8 11.0 7.7 6.9 12.8 10.9 15.2 12.7 9.1 7.1 21.2 13.0 6.0 11.6 5.1 10.7 17.5 9.5 11.6 7.4 14.1 6.0 15.8 5.9 14.4 17.2 5.8 15.0 6.2 12.5 16.7 5.7 9.3 10.8 23.3 5.9 15.4 6.7 9.6 7.4 7.1 5.7 7.1 6.7 9.3 7.4 5.7 9.5 8.3 3.8 6.8 8.4 5.8 21.3 7.1 3.8 4.8 5.7 3.6 6.6 3.3 4.3 4.9 4.1 5.1 4.1 6.3 4.5 3.2 2.3 7.0 5.0 4.9 5.9 11.5 11.6 11.9 13.6 11.5 13.1 12.9 11.7 13.1 11.3 13.8 11.1 63.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 453.9 0.0 0.0 0.0 0.0 283.4 25.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.0 279.7 52.8 0.0 0.0 0.0 0.0 0.0 0.0 531.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.0 0.0 0.0 0.0 183.5 5.3 0.0 0.0 0.0 MICOS13 "C19orf70, MIC13, P117, QIL1" ENSG00000174917 "Mitochondrial contact site and cristae organizing system subunit 13" Q5XKP0 19 5678421-5680516 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 344.8;Cytotrophoblasts: 154.4;Extravillous trophoblasts: 196.7;Hofbauer cells: 242.2;Syncytiotrophoblasts: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042672 Approved Supported Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria Nucleoplasm "HPA042672: AB_10794531" "unprognostic (9.54e-2)" "unprognostic (4.90e-3)" "unprognostic (3.04e-1)" "unprognostic (3.21e-3)" "unprognostic (1.52e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (2.53e-3)" "unprognostic (2.14e-2)" "unprognostic (9.32e-2)" "unprognostic (2.50e-2)" "unprognostic (1.57e-1)" "prognostic favorable (7.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.94e-2)" "unprognostic (2.27e-1)" "unprognostic (5.47e-2)" 71.0 68.8 139.7 48.4 143.6 54.1 59.3 153.6 180.2 44.4 137.0 76.5 78.6 46.9 44.0 86.9 67.3 53.8 271.2 141.2 154.5 93.5 78.3 44.2 60.4 148.7 143.8 44.7 86.7 97.4 59.8 37.9 147.1 50.1 40.7 18.6 95.3 60.7 279.3 59.7 66.7 43.8 142.0 45.0 61.8 149.2 151.4 38.8 57.9 186.5 35.2 61.3 49.3 146.7 175.7 167.9 43.4 87.6 98.3 117.1 58.7 100.7 121.0 142.6 120.3 132.6 85.2 82.0 157.6 105.2 65.3 124.7 25.8 175.5 34.6 128.9 311.9 76.1 101.2 153.4 162.5 105.8 79.2 133.0 157.9 71.5 92.6 68.0 104.9 112.5 120.5 220.6 101.2 186.3 145.7 129.2 45.1 118.5 474.3 79.5 57.8 286.7 145.3 126.1 111.5 134.8 37.8 198.1 152.2 25.2 128.3 123.8 87.4 121.9 50.5 217.4 169.2 315.8 280.6 66.9 174.5 183.6 126.0 76.8 214.3 77.8 198.9 274.7 237.5 291.6 228.5 225.8 261.4 235.7 222.8 211.3 29.6 192.1 238.8 302.5 211.1 278.1 139.7 143.6 153.6 180.2 141.2 154.5 148.7 143.8 147.1 142.0 151.4 146.7 44.6 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 344.8 0.0 0.0 0.0 0.0 154.4 24.5 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 196.7 46.9 0.0 0.0 0.0 0.0 0.0 0.0 242.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 125.9 5.8 0.0 0.0 0.0 MICU1 "CALC, CBARA1, EFHA3, FLJ12684" ENSG00000107745 "Mitochondrial calcium uptake 1" Q9BPX6 10 72367327-72626191 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" Allergen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 185.5;Inhibitory neurons: 205.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037479, HPA037480" Approved Supported Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA037479: AB_2675495, HPA037480: AB_10696934" "unprognostic (8.18e-2)" "unprognostic (6.98e-3)" "unprognostic (6.71e-2)" "unprognostic (8.06e-2)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (8.91e-2)" "unprognostic (3.60e-2)" "unprognostic (2.96e-3)" "unprognostic (3.38e-2)" "unprognostic (7.43e-2)" "unprognostic (2.23e-2)" "prognostic favorable (4.66e-7)" "unprognostic (1.70e-1)" "unprognostic (1.55e-1)" "unprognostic (5.35e-2)" "unprognostic (6.70e-2)" 30.9 55.3 34.4 21.2 37.2 34.2 26.4 51.4 47.1 28.8 27.8 30.1 37.4 36.5 23.8 20.7 34.6 32.3 43.9 37.8 32.2 105.3 116.7 29.6 20.1 32.2 30.7 41.6 20.0 43.3 24.4 23.6 33.7 24.8 32.9 31.5 20.8 22.3 72.2 29.0 32.7 38.4 29.0 27.0 43.3 20.2 30.4 26.1 22.9 76.9 21.6 30.8 21.7 34.1 42.2 71.8 45.4 53.3 70.8 66.6 20.6 45.8 101.6 65.7 89.8 42.2 77.2 56.8 37.3 63.5 54.0 49.1 57.7 40.7 76.9 51.9 46.6 38.3 37.1 61.2 56.4 53.3 40.1 66.6 36.2 72.4 66.5 90.4 57.7 53.4 60.0 64.5 77.6 37.9 46.7 49.9 19.0 45.0 17.3 50.5 60.9 37.4 80.8 31.0 34.8 49.8 54.2 65.9 42.0 45.2 39.3 50.5 36.2 32.6 50.1 65.7 38.4 33.9 62.6 39.2 65.1 69.6 22.5 21.5 60.0 110.8 16.8 49.8 14.7 15.1 14.7 15.5 26.0 17.5 14.4 12.0 48.8 15.2 54.5 16.5 15.3 35.4 34.4 37.2 51.4 47.1 37.8 32.2 32.2 30.7 33.7 29.0 30.4 34.1 30.4 54.5 36.0 47.7 23.4 9.9 16.0 22.6 14.2 31.9 25.3 19.6 35.8 25.8 38.3 35.0 20.9 20.7 16.9 25.9 80.3 35.6 10.7 42.0 43.0 22.7 14.4 25.0 185.5 26.7 18.8 31.1 45.9 48.2 18.3 31.5 23.9 60.4 34.8 16.8 205.9 24.4 16.2 36.9 13.4 12.5 26.8 40.1 12.4 64.6 38.0 51.3 10.3 146.8 97.5 51.4 24.9 25.9 25.0 10.7 29.3 110.7 34.0 33.8 6.6 29.0 27.2 54.5 40.0 14.2 14.2 21.5 19.0 73.4 23.6 14.2 MICU2 EFHA1 ENSG00000165487 "Mitochondrial calcium uptake 2" Q8IYU8 13 21492691-21604181 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045511, HPA058790" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Mitochondria "HPA045511: AB_10959894, HPA058790: AB_2683821" "unprognostic (4.32e-3)" "unprognostic (1.50e-2)" "unprognostic (2.00e-1)" "unprognostic (7.01e-2)" "unprognostic (9.80e-2)" "unprognostic (4.11e-2)" "unprognostic (1.47e-2)" "unprognostic (8.01e-2)" "unprognostic (4.79e-3)" "unprognostic (1.63e-3)" "unprognostic (1.58e-1)" "unprognostic (1.56e-1)" "prognostic favorable (1.40e-7)" "unprognostic (3.81e-2)" "unprognostic (8.94e-2)" "unprognostic (5.15e-2)" "unprognostic (3.50e-1)" 22.6 44.4 19.3 24.5 21.0 36.3 32.4 23.9 29.7 26.2 24.2 37.6 26.5 22.1 27.8 23.2 25.1 20.2 57.5 20.4 20.4 76.3 32.2 23.0 26.9 21.8 20.6 22.7 21.3 45.9 27.0 24.5 20.2 28.5 34.1 45.7 23.4 22.1 56.4 22.9 27.4 21.1 20.8 22.6 30.6 27.0 19.7 28.8 37.6 61.5 29.7 23.5 18.7 24.2 35.2 20.0 46.2 29.6 40.4 53.8 39.7 58.3 47.5 60.8 42.0 29.0 55.6 54.4 36.8 56.0 31.3 45.9 45.9 49.1 83.4 55.5 46.5 94.2 20.5 34.3 48.7 71.4 52.7 46.8 47.7 34.5 24.4 54.4 41.2 50.5 33.9 23.9 100.3 30.8 47.9 68.1 31.5 123.2 30.3 51.9 117.2 36.6 121.3 28.6 36.9 28.6 39.8 46.4 39.6 40.2 45.3 66.7 51.1 26.4 23.6 54.1 48.9 17.7 24.8 39.6 26.1 59.0 66.8 34.0 24.8 35.1 30.6 30.5 28.0 42.1 26.9 30.9 27.3 24.4 23.7 30.2 23.3 30.2 25.6 25.1 40.3 23.9 19.3 21.0 23.9 29.7 20.4 20.4 21.8 20.6 20.2 20.8 19.7 24.2 22.0 38.5 26.8 70.2 51.3 30.0 39.8 51.9 26.2 27.1 24.0 17.8 74.5 30.0 46.8 51.5 22.9 60.7 31.8 52.2 144.8 43.3 40.7 39.7 28.4 24.3 30.5 65.2 126.1 27.2 42.6 32.0 27.0 28.7 24.7 26.5 17.9 24.0 36.5 42.1 142.5 25.7 57.0 28.8 22.1 16.2 33.8 28.5 48.0 55.3 43.1 63.9 43.3 77.9 121.7 36.9 51.7 36.1 29.3 27.8 31.3 108.4 56.0 49.0 59.2 37.6 30.7 86.9 48.5 23.0 25.6 70.3 45.5 47.4 34.2 30.0 MIER1 "hMI-ER1, KIAA1610, MI-ER1" ENSG00000198160 "MIER1 transcriptional regulator" Q8N108 1 66924895-66988619 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 97.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019589, HPA050306" Enhanced Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA019589: AB_1853953, HPA050306: AB_2681080" "unprognostic (3.38e-3)" "unprognostic (1.34e-1)" "prognostic favorable (4.96e-4)" "unprognostic (1.63e-1)" "prognostic favorable (3.44e-8)" "unprognostic (1.61e-1)" "unprognostic (3.15e-3)" "unprognostic (1.32e-1)" "unprognostic (1.05e-1)" "unprognostic (3.92e-3)" "unprognostic (4.48e-3)" "unprognostic (2.57e-2)" "unprognostic (2.81e-2)" "unprognostic (2.25e-2)" "unprognostic (2.73e-1)" "unprognostic (5.15e-2)" "unprognostic (2.45e-2)" 18.6 20.8 10.7 18.4 12.4 97.9 16.5 12.8 13.8 19.7 10.4 27.5 15.5 18.7 13.5 16.6 13.1 18.8 11.4 8.9 11.6 16.2 24.6 16.3 20.7 11.4 10.8 20.7 9.1 12.3 7.8 20.2 12.1 14.4 23.5 18.9 11.3 17.1 8.2 12.6 16.1 17.9 11.0 20.0 18.8 18.2 10.9 24.4 14.1 13.1 19.6 18.5 11.8 14.8 29.7 16.8 20.4 36.8 41.9 27.2 22.7 30.3 33.5 29.7 32.1 13.7 17.7 29.8 11.1 34.3 26.7 19.2 24.9 33.1 42.5 34.6 19.3 65.2 44.0 21.8 33.2 52.5 36.9 28.2 24.5 33.3 34.3 34.5 32.9 35.6 34.6 25.6 35.6 9.4 76.0 18.8 29.2 13.4 10.8 32.7 49.1 20.4 25.5 32.6 12.0 23.7 45.5 27.9 29.8 19.3 14.4 34.2 39.7 34.5 24.2 33.7 28.4 31.8 31.6 42.5 28.1 22.5 21.2 43.7 10.9 26.8 18.5 12.4 21.5 11.2 16.4 16.5 8.6 13.1 16.6 16.3 37.1 15.8 20.8 11.7 15.1 8.7 10.7 12.4 12.8 13.8 8.9 11.6 11.4 10.8 12.1 11.0 10.9 14.8 77.4 16.0 45.7 40.8 65.7 48.3 40.5 37.3 51.2 37.7 45.9 44.7 32.9 35.8 35.0 27.6 25.0 41.6 92.1 125.7 45.0 36.8 55.3 54.3 56.8 54.7 42.1 50.1 50.6 40.6 26.8 62.8 34.1 70.6 92.4 48.9 40.4 50.3 22.2 40.4 48.6 54.6 34.6 45.6 38.3 49.3 81.4 56.1 14.2 46.9 69.8 68.7 86.5 40.7 83.8 54.1 77.7 93.3 48.1 52.4 41.3 34.1 35.2 48.5 78.9 64.7 77.5 53.0 62.9 42.0 34.7 34.3 97.1 35.7 53.5 60.4 MIF4GD "AD023, MGC45027, MIFD, SLIP1" ENSG00000125457 "MIF4G domain containing" A9UHW6 17 75266228-75271231 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051222 Approved Supported "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 6: T47d - Mammary gland" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoli "Golgi apparatus, Cytosol" "HPA051222: AB_2681393" "unprognostic (1.05e-1)" "unprognostic (9.17e-2)" "unprognostic (1.94e-2)" "unprognostic (3.82e-3)" "unprognostic (2.92e-1)" "unprognostic (1.31e-1)" "unprognostic (2.36e-2)" "unprognostic (4.21e-2)" "unprognostic (1.44e-1)" "unprognostic (8.15e-2)" "prognostic favorable (2.70e-4)" "unprognostic (2.18e-1)" "unprognostic (9.20e-2)" "unprognostic (9.88e-2)" "unprognostic (2.29e-1)" "unprognostic (7.12e-2)" "unprognostic (7.31e-2)" 29.7 22.5 15.6 18.7 17.7 43.6 23.4 16.9 16.4 22.2 12.9 24.1 12.6 23.1 8.2 28.4 18.2 17.3 23.0 15.1 16.5 24.5 17.6 25.4 33.2 17.3 17.2 14.2 27.6 21.5 11.8 12.3 18.4 16.4 15.1 6.0 19.9 14.4 63.2 32.8 25.1 16.9 17.4 35.7 19.5 17.9 16.6 24.5 16.6 26.8 27.0 23.7 21.6 18.6 25.6 43.5 8.9 20.3 17.9 5.4 12.7 6.2 19.1 13.0 9.5 14.4 29.8 38.7 11.7 11.9 14.6 19.8 13.6 24.4 10.5 19.2 27.3 20.2 16.5 14.1 19.9 18.9 20.4 4.8 37.7 8.7 39.7 17.7 27.3 44.7 25.7 50.0 3.6 47.6 58.6 39.0 3.5 29.0 21.3 36.6 11.3 58.6 29.4 14.1 11.7 17.1 13.9 34.5 33.0 23.4 65.9 41.2 9.7 5.6 13.8 7.2 12.1 67.8 17.5 33.3 11.7 31.3 8.7 27.5 77.6 44.4 54.6 41.1 56.6 49.3 43.0 47.9 91.4 44.2 37.1 39.9 13.1 56.4 55.4 226.4 68.3 60.3 15.6 17.7 16.9 16.4 15.1 16.5 17.3 17.2 18.4 17.4 16.6 18.6 33.2 0.0 11.0 3.3 30.5 11.5 14.8 11.1 5.2 3.8 23.8 23.4 4.2 31.5 15.3 12.9 0.0 15.0 73.4 12.1 21.5 45.2 32.6 11.6 4.7 20.1 15.6 11.1 3.0 43.4 9.4 12.3 9.2 12.0 31.8 13.0 17.5 9.0 44.9 1.7 3.1 18.0 28.5 47.4 45.1 19.8 9.3 45.4 16.0 7.5 47.7 30.5 53.5 5.0 8.2 24.8 22.7 15.8 22.5 14.3 22.3 29.3 17.6 6.0 19.7 13.0 22.0 19.6 22.1 23.2 18.9 9.3 33.5 7.4 16.9 14.1 MINPP1 MIPP ENSG00000107789 "Multiple inositol-polyphosphate phosphatase 1" Q9UNW1 10 87504875-87553461 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Erythroid cells: 288.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026859 Approved "Intracellular and membrane" NA NA 370000000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA026859: AB_1853961" "unprognostic (9.15e-2)" "unprognostic (8.76e-3)" "unprognostic (2.08e-2)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" "unprognostic (5.20e-3)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (4.55e-1)" "unprognostic (2.07e-2)" "unprognostic (6.54e-2)" "unprognostic (6.50e-3)" "prognostic unfavorable (6.98e-5)" "unprognostic (2.43e-1)" "unprognostic (2.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.01e-2)" 8.5 21.3 6.6 7.2 6.7 31.1 9.4 6.9 9.1 8.8 9.4 12.6 17.6 7.0 10.0 3.6 8.5 8.4 5.8 6.8 8.0 17.5 29.1 8.3 7.7 6.4 6.8 8.8 11.9 9.0 8.1 18.9 6.4 11.7 12.9 11.9 6.9 7.6 4.9 9.1 13.6 7.6 6.9 6.9 8.5 7.9 7.7 8.1 11.6 5.7 7.0 8.6 5.7 7.4 18.6 28.1 28.1 40.9 46.4 38.1 23.2 29.5 51.1 28.8 38.3 15.0 35.5 16.4 27.0 35.9 19.4 28.2 29.9 27.1 33.2 37.1 35.7 41.1 10.4 55.7 34.6 18.0 36.0 33.7 34.7 32.6 19.5 52.5 37.0 14.3 24.5 75.9 34.4 13.8 11.9 25.6 20.0 14.2 20.2 0.0 15.8 11.0 38.5 10.4 10.2 31.5 28.1 5.9 51.5 31.5 16.7 14.7 32.4 18.3 21.9 22.1 28.7 24.5 27.1 4.2 29.3 26.8 13.7 10.5 10.8 4.9 11.5 13.8 10.1 8.7 10.8 13.0 14.3 8.2 10.2 11.4 0.7 11.7 12.5 8.2 17.3 10.5 6.6 6.7 6.9 9.1 6.8 8.0 6.4 6.8 6.4 6.9 7.7 7.4 11.7 6.4 12.8 9.1 8.1 2.8 8.3 25.5 8.0 14.4 9.0 4.3 4.9 15.7 16.2 7.3 2.1 20.4 4.9 14.0 5.9 17.2 15.9 7.1 13.4 10.5 13.1 288.9 18.3 16.7 19.2 17.9 7.1 6.7 24.7 17.8 16.4 58.3 12.9 10.1 20.8 25.5 20.3 16.0 5.8 4.0 9.3 8.7 10.6 7.5 11.7 11.1 10.3 25.6 19.1 10.5 17.2 8.2 18.6 6.8 17.1 26.0 19.0 14.8 0.0 4.8 11.1 10.6 12.1 4.0 3.4 8.1 8.2 13.7 11.6 4.4 MKNK1 MNK1 ENSG00000079277 "MAPK interacting serine/threonine kinase 1" Q9BUB5 1 46557407-46616843 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 128.6" "Cell type enhanced" "Detected in all" "Hofbauer cells: 142.8;Microglial cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB027355, CAB037310, HPA071293" Approved Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB027355: AB_2266303, CAB037310: AB_1854049, HPA071293: AB_2686382" "unprognostic (4.05e-3)" "prognostic favorable (7.05e-4)" "unprognostic (5.28e-2)" "unprognostic (3.47e-2)" "unprognostic (1.64e-1)" "unprognostic (7.38e-2)" "prognostic unfavorable (1.24e-5)" "unprognostic (3.50e-2)" "unprognostic (1.77e-1)" "unprognostic (2.60e-1)" "unprognostic (1.50e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (1.51e-5)" "unprognostic (7.02e-2)" "unprognostic (3.19e-2)" "unprognostic (4.67e-1)" "unprognostic (5.67e-3)" 30.6 21.8 15.5 23.5 14.4 30.3 23.1 19.0 18.0 22.8 17.0 27.4 15.6 18.5 12.0 23.5 21.4 16.1 22.3 15.1 14.6 17.5 21.8 31.5 17.0 14.2 13.3 19.0 128.6 12.0 18.4 22.1 14.4 19.4 17.7 3.9 16.7 8.5 23.9 18.0 24.9 18.4 13.7 48.1 23.1 12.4 16.6 22.6 16.2 23.9 13.8 20.1 20.7 16.5 34.1 21.7 13.5 15.7 12.0 17.9 18.0 16.7 16.4 20.7 27.1 26.4 13.5 23.1 20.2 17.8 23.0 38.5 23.8 27.5 23.1 37.7 21.4 47.8 28.3 21.7 17.3 25.4 34.8 22.0 17.7 25.2 13.4 10.8 24.1 26.2 24.7 16.6 12.2 21.5 18.3 21.8 9.9 19.6 24.8 16.7 30.5 22.1 20.2 35.2 10.4 9.0 32.3 27.9 25.6 26.5 21.5 28.6 18.5 7.6 1.4 22.2 19.9 12.6 23.7 21.2 14.6 31.9 13.4 9.7 26.3 36.1 15.3 25.7 44.7 9.9 12.9 14.2 13.1 11.6 9.2 13.9 69.7 11.2 20.6 9.7 10.6 14.5 15.5 14.4 19.0 18.0 15.1 14.6 14.2 13.3 14.4 13.7 16.6 16.5 20.3 12.8 21.5 41.4 15.3 13.9 17.8 15.2 9.1 19.4 17.8 12.3 19.2 15.7 17.8 22.0 2.1 21.6 23.7 27.9 7.9 18.9 15.5 12.5 12.8 18.3 16.8 21.9 42.2 37.1 34.2 20.5 11.7 13.3 12.0 22.8 18.2 22.7 142.8 18.5 52.7 12.0 4.1 84.5 61.0 23.8 21.5 49.9 10.6 100.2 26.7 5.2 21.6 21.6 8.5 32.3 17.7 36.5 13.3 19.5 27.8 15.7 11.1 5.0 6.6 31.2 15.0 15.3 17.2 22.6 11.1 18.5 25.2 35.1 15.0 29.6 MKRN1 RNF61 ENSG00000133606 "Makorin ring finger protein 1" Q9UHC7 7 140453033-140479536 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 328.0;Erythroid cells: 424.2;Late spermatids: 340.6" "Cancer enriched" "Detected in all" 5 "testis cancer: 129.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000567 Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Cytosol" "HPA000567: AB_1079299" "unprognostic (9.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "unprognostic (7.60e-3)" "unprognostic (1.65e-2)" "unprognostic (2.41e-1)" "unprognostic (4.87e-3)" "unprognostic (1.24e-2)" "unprognostic (8.02e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-1)" "unprognostic (1.35e-1)" "unprognostic (2.89e-3)" "unprognostic (5.76e-2)" "unprognostic (2.42e-1)" "unprognostic (1.22e-1)" "unprognostic (1.22e-2)" 39.5 36.8 50.9 47.9 50.7 202.6 47.8 52.6 57.1 43.0 46.6 97.9 69.2 46.7 43.3 49.0 51.3 37.5 64.6 51.0 53.7 47.9 42.7 46.9 49.7 57.6 50.7 56.5 58.1 66.8 42.3 43.0 58.9 48.6 80.1 58.6 56.5 44.4 84.0 51.7 65.8 43.5 50.2 52.7 53.9 123.2 55.6 47.1 46.9 58.5 56.4 45.7 38.9 50.9 96.5 72.3 55.6 83.1 86.5 75.5 78.2 64.6 83.3 49.8 57.2 30.0 98.8 69.4 98.4 63.4 99.2 45.7 63.2 71.2 62.8 138.0 55.6 72.1 43.5 55.9 69.4 62.5 107.1 75.4 105.1 56.2 52.8 81.9 50.8 46.9 58.0 84.8 49.1 82.6 73.4 114.2 143.3 80.7 53.6 52.4 47.4 107.6 80.8 109.2 76.6 79.1 80.8 108.5 120.6 81.6 53.3 53.5 71.9 34.9 27.4 85.8 59.8 200.2 159.2 60.9 99.3 96.1 73.3 58.6 22.5 100.4 15.4 21.3 18.0 33.6 29.5 23.0 18.0 32.9 39.9 25.5 42.5 31.1 26.5 6.0 35.3 15.3 50.9 50.7 52.6 57.1 51.0 53.7 57.6 50.7 58.9 50.2 55.6 50.9 28.4 51.3 37.2 13.4 76.8 82.1 66.6 57.1 57.5 61.5 60.9 36.2 57.7 67.2 71.1 42.3 35.5 75.8 54.0 172.1 103.7 69.8 328.0 58.4 30.6 34.2 97.3 424.2 28.9 67.8 96.6 43.3 38.7 65.7 37.4 79.5 45.7 45.0 59.5 119.5 28.0 107.7 89.5 95.9 93.3 340.6 66.5 86.3 69.4 22.5 119.0 61.4 92.7 15.1 22.1 57.6 140.3 62.4 41.8 101.2 112.4 54.4 70.0 46.4 46.0 34.7 53.3 303.0 60.1 62.4 95.5 138.0 62.9 39.6 103.5 145.9 MLEC KIAA0152 ENSG00000110917 Malectin Q14165 12 120687149-120701859 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Undifferentiated cells: 397.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 880000 "Cluster 52: Eosinophils - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.50e-1)" "unprognostic (1.74e-1)" "unprognostic (2.01e-2)" "prognostic favorable (9.60e-6)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (5.41e-2)" "unprognostic (3.94e-1)" "unprognostic (3.39e-1)" "unprognostic (9.77e-2)" "unprognostic (5.90e-2)" "unprognostic (1.76e-1)" "unprognostic (1.15e-2)" "prognostic favorable (8.77e-4)" "unprognostic (1.98e-1)" "unprognostic (7.88e-2)" "unprognostic (1.05e-1)" 51.7 93.1 35.4 51.8 36.7 34.6 44.3 33.0 34.5 52.8 40.3 127.0 78.3 37.2 138.1 24.5 48.5 48.5 65.9 34.7 40.0 73.5 78.2 34.9 30.3 42.3 39.4 49.2 62.7 101.2 36.7 45.7 37.8 62.4 117.3 25.3 50.7 64.9 79.8 27.8 86.0 50.0 40.0 30.1 45.3 69.1 42.9 33.3 101.0 82.9 37.3 34.1 17.4 37.6 122.7 177.9 113.6 151.8 196.3 107.4 127.9 144.5 126.3 108.9 80.1 127.5 75.1 100.3 129.0 142.2 85.4 101.9 140.4 87.4 138.7 86.5 76.9 142.4 79.4 100.6 72.1 199.3 123.1 82.2 82.7 116.0 91.4 174.1 97.2 93.9 85.9 112.2 116.3 127.8 106.4 122.2 158.1 156.6 91.7 115.7 82.0 109.1 132.2 204.0 58.2 69.2 166.5 85.9 86.0 143.0 127.0 144.6 79.2 115.8 108.5 112.8 100.3 83.3 165.0 76.8 147.6 147.9 120.1 0.5 6.0 8.0 3.8 7.5 4.1 4.7 2.3 3.4 5.0 6.9 4.0 3.4 1.6 3.9 6.5 18.6 2.4 2.2 35.4 36.7 33.0 34.5 34.7 40.0 42.3 39.4 37.8 40.0 42.9 37.6 151.4 25.6 62.2 23.2 65.7 72.8 70.6 32.0 55.2 40.9 99.7 76.3 145.3 97.2 40.0 86.5 45.9 88.4 105.7 155.3 37.2 134.2 243.3 78.3 127.6 94.1 80.3 68.5 21.4 183.7 176.9 90.5 69.3 80.2 49.5 99.8 27.1 206.1 126.8 84.1 24.7 199.2 30.5 61.7 73.2 228.0 82.6 70.1 193.9 34.7 56.4 81.8 74.2 32.2 23.0 95.8 86.0 108.0 217.4 152.6 135.4 121.7 41.9 45.3 85.5 61.4 78.5 165.6 153.4 52.8 58.7 115.6 51.2 142.5 397.0 82.2 MLH1 "COCA2, FCC2, HNPCC, HNPCC2" ENSG00000076242 "MutL homolog 1" P40692 3 36993350-37050846 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013294, HPA052707, HPA060714, CAB070868" Supported Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "CAB013294: AB_2533406, CAB070868: , HPA052707: AB_2681923, HPA060714: AB_2684348" "unprognostic (1.26e-2)" "unprognostic (3.88e-3)" "unprognostic (2.36e-2)" "unprognostic (1.82e-1)" "unprognostic (3.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (8.24e-5)" "unprognostic (3.36e-2)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (8.54e-2)" "unprognostic (8.63e-3)" "unprognostic (2.10e-3)" "unprognostic (4.37e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (8.86e-2)" 15.6 17.9 7.3 17.4 8.0 22.1 15.4 7.1 9.1 17.4 7.6 17.4 12.0 16.3 14.0 14.3 14.9 11.1 35.4 6.9 8.3 16.0 19.1 15.8 21.9 8.6 7.4 15.1 16.6 22.4 22.7 14.8 7.6 16.2 14.5 9.6 12.1 14.0 49.1 13.4 13.4 19.2 7.1 18.8 15.5 25.4 7.7 28.4 19.2 42.2 24.3 17.2 14.0 9.0 37.1 56.7 66.7 0.2 25.9 34.5 30.7 54.7 44.4 64.1 62.3 43.4 40.1 92.2 25.0 44.1 33.6 24.7 65.2 45.8 68.5 42.2 32.1 68.1 42.3 54.9 23.2 81.9 40.5 28.4 29.0 54.8 57.8 21.9 37.6 55.0 86.0 32.0 66.2 27.6 81.0 22.2 49.4 38.4 31.6 4.6 90.6 40.2 35.1 39.3 14.2 36.1 52.1 56.9 32.7 33.3 79.9 55.6 28.8 46.0 50.5 44.0 65.9 29.1 93.7 88.1 37.8 71.9 45.7 12.6 12.5 15.1 12.7 22.6 9.8 11.3 7.7 11.4 14.3 9.7 8.4 9.6 2.6 7.8 29.2 5.9 15.0 11.0 7.3 8.0 7.1 9.1 6.9 8.3 8.6 7.4 7.6 7.1 7.7 9.0 10.8 25.6 15.8 22.9 18.5 7.1 12.4 18.7 7.4 18.5 9.6 9.7 41.8 12.8 15.8 11.0 10.4 33.4 16.0 6.1 19.6 14.6 31.3 12.5 11.3 10.7 5.4 19.0 18.5 14.7 26.9 14.4 12.2 9.5 7.6 13.0 13.6 14.9 20.1 3.3 21.6 8.6 16.2 16.3 8.9 13.2 11.1 13.8 8.8 10.3 18.2 15.9 11.3 27.2 31.3 9.3 7.4 13.9 22.1 6.4 5.3 12.9 16.5 18.1 13.1 10.0 14.0 58.6 29.3 9.3 5.5 20.0 15.9 14.8 8.4 6.5 MLN ENSG00000096395 Motilin P12872 6 33794673-33804003 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 331 "intestine: 254.8" "Cell type enriched" "Detected in single" 11 "Enteroendocrine cells: 3.5" "Cancer enriched" "Detected in some" 6 "testis cancer: 5.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.0;SuSa: 1.1;TIME: 1.3" "Low region specificity" "Detected in many" "HPA069392, HPA077622" Enhanced "Secreted to blood" NA NA 450000 200000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA069392: AB_2686136, HPA077622: " "unprognostic (7.70e-2)" "unprognostic (6.70e-2)" "unprognostic (4.44e-2)" "unprognostic (3.14e-1)" 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.5 254.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.1 0.3 43.3 0.0 0.2 0.0 0.1 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.5 0.7 0.4 0.7 0.2 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MLXIP "bHLHe36, KIAA0867, MIR, MONDOA" ENSG00000175727 "MLX interacting protein" Q9HAP2 12 122078756-122147344 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 130.0" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 769.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023084 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA023084: AB_1854005" "unprognostic (4.49e-1)" "unprognostic (8.89e-2)" "unprognostic (8.48e-2)" "unprognostic (3.60e-1)" "unprognostic (3.06e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (2.72e-1)" "unprognostic (6.19e-2)" "unprognostic (3.53e-2)" "unprognostic (1.71e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.92e-4)" "unprognostic (3.04e-1)" "unprognostic (1.98e-1)" "unprognostic (5.75e-2)" "unprognostic (7.40e-2)" 26.0 28.5 10.6 29.7 9.5 35.8 21.0 14.3 12.1 24.4 10.0 74.8 26.6 30.4 25.3 15.5 33.3 21.3 23.3 9.7 9.7 25.3 31.1 29.9 17.2 10.5 8.7 47.2 61.5 12.8 21.4 12.5 11.0 27.2 44.2 11.1 32.0 18.9 130.0 25.1 38.9 32.2 7.3 35.1 40.8 16.4 9.9 14.1 41.5 42.0 13.5 45.9 17.3 13.3 25.1 21.6 12.5 26.3 20.1 16.8 4.7 13.8 8.3 6.3 5.3 23.2 9.8 8.4 16.5 13.3 9.3 28.2 24.0 31.8 7.9 16.4 24.9 28.1 15.8 18.3 33.7 12.5 18.4 29.5 24.9 16.2 20.2 17.0 33.1 22.4 54.8 8.0 13.8 16.9 17.5 30.5 12.0 17.8 14.6 26.1 27.4 11.5 19.3 28.2 21.0 12.0 35.3 17.0 18.3 11.2 17.6 27.9 49.1 14.4 13.9 25.6 20.4 18.6 13.6 11.7 18.6 17.2 22.8 2.5 3.7 1.2 1.9 1.4 1.4 1.8 1.9 1.6 2.3 2.3 2.7 3.3 2.9 2.1 2.4 3.1 1.7 1.9 10.6 9.5 14.3 12.1 9.7 9.7 10.5 8.7 11.0 7.3 9.9 13.3 66.7 25.6 31.2 18.6 31.2 57.2 36.5 19.0 25.0 52.0 37.2 26.0 17.4 54.3 29.8 31.3 769.4 2.8 32.9 195.2 13.7 56.7 22.7 58.5 71.1 44.4 180.6 59.1 31.7 149.6 2.8 44.4 29.6 60.6 8.8 23.2 72.5 32.9 28.0 28.6 32.1 128.9 32.6 65.7 65.7 39.8 50.7 39.4 32.0 28.1 57.2 8.1 30.9 26.2 29.3 127.5 105.3 88.8 35.0 59.0 36.2 14.3 58.0 33.5 19.7 66.2 39.9 20.7 25.0 20.0 61.1 5.3 29.8 42.9 231.2 47.7 MLXIPL "bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH" ENSG00000009950 "MLX interacting protein like" Q9NP71 7 73593194-73624543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 609.7" "Group enriched" "Detected in many" 4 "Cholangiocytes: 84.4;Enteroendocrine cells: 90.1;Hepatocytes: 286.6;Proximal enterocytes: 108.9" "Cancer enriched" "Detected in many" 6 "liver cancer: 60.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 46.5;K-562: 15.2;SCLC-21H: 25.5;T-47d: 11.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064640 Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA064640: AB_2685309" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.18e-2)" "unprognostic (4.86e-2)" "unprognostic (5.04e-1)" "unprognostic (1.06e-3)" "unprognostic (3.46e-3)" "unprognostic (9.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (6.13e-3)" "unprognostic (4.91e-2)" "unprognostic (2.25e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (2.46e-2)" "unprognostic (7.72e-3)" 72.3 85.1 5.5 0.7 4.1 0.2 51.2 16.3 9.4 3.0 0.2 7.8 58.8 0.6 16.3 3.4 12.9 5.5 3.5 4.5 1.4 36.2 609.7 2.7 0.0 5.6 1.4 4.9 23.1 6.3 13.4 0.0 6.1 3.7 1.5 0.7 8.7 0.8 58.1 4.5 46.8 0.5 1.3 0.3 4.7 30.9 2.2 0.9 7.3 13.8 0.0 2.0 2.7 2.1 0.2 2.5 0.0 5.9 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.3 7.5 0.0 0.3 0.0 0.6 1.2 0.0 0.0 0.0 0.2 6.1 0.0 4.8 46.5 1.3 0.2 1.7 0.8 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.1 6.3 0.1 0.0 0.7 8.2 1.0 0.0 0.0 1.2 0.0 0.1 25.5 0.7 1.0 4.4 0.0 0.1 11.4 6.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 4.1 16.3 9.4 4.5 1.4 5.6 1.4 6.1 1.3 2.2 2.1 0.6 0.0 16.2 2.3 1.6 1.1 4.8 0.6 0.6 9.9 1.4 1.3 3.4 84.4 4.7 3.7 20.9 0.1 0.3 3.2 1.9 2.9 3.2 0.7 0.2 2.5 90.1 16.0 33.4 1.0 0.1 6.5 4.6 0.8 0.0 0.1 12.8 286.6 0.4 1.7 29.1 19.6 0.0 11.2 1.5 1.2 2.8 2.8 7.2 30.9 0.2 2.0 1.0 2.0 0.9 1.4 13.9 1.2 0.1 2.2 108.9 14.1 3.2 6.5 0.0 23.9 1.0 5.1 1.1 0.5 0.9 0.5 1.7 0.0 31.9 4.0 MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183704 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 333.5;kidney: 302.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 273.3;Proximal enterocytes: 372.4;Proximal tubular cells: 125.7;Syncytiotrophoblasts: 126.0" "Cancer enhanced" "Detected in many" "prostate cancer: 17.6" "Group enriched" "Detected in many" 5 "basal ganglia: 17.3;medulla oblongata: 9.3;pons: 10.9;thalamus: 4.6" "Immune cell enriched" "Detected in some" 122 "neutrophil: 139.4" "Lineage enriched" "Detected in many" 122 "granulocytes: 139.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 684.4;BJ hTERT+: 1116.9;HSkMC: 651.1" "Region enhanced" "Detected in many" "basal ganglia: 28.1" "Group enriched" "Detected in many" 4 "basal ganglia: 32.3;olfactory bulb: 8.5;spinal cord: 15.9" "CAB000013, HPA052583, HPA056072" Enhanced NA NA 320000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "CAB000013: AB_563478, HPA052583: AB_2681872, HPA056072: AB_2683027" "unprognostic (1.36e-1)" "unprognostic (1.02e-3)" "unprognostic (8.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.78e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (7.30e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-1)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (1.37e-2)" 103.9 1.0 0.7 4.5 17.3 11.5 38.5 1.5 1.9 22.7 0.3 1.9 333.5 13.3 22.5 2.3 1.9 13.4 4.3 0.1 0.6 302.5 56.1 27.6 10.3 9.3 2.3 0.9 1.2 0.5 0.6 73.0 10.9 79.6 3.4 0.1 6.1 44.5 20.3 1.9 289.7 1.5 0.9 7.9 1.6 1.3 4.6 16.6 1.2 23.5 12.3 6.0 7.6 0.4 0.1 0.0 0.9 0.3 280.1 684.4 1.6 160.3 1116.9 82.2 209.8 0.0 0.3 172.9 0.1 130.1 107.4 0.5 5.2 6.1 201.3 0.0 0.8 0.0 0.1 0.2 229.6 0.0 0.0 651.1 1.0 40.4 308.1 89.4 59.5 0.4 0.2 0.3 135.1 0.7 0.4 1.0 6.1 0.5 1.1 303.3 139.9 1.6 5.2 1.9 0.5 1.5 0.1 0.5 31.9 68.3 0.2 0.2 165.8 356.4 0.8 115.7 27.9 0.1 0.0 217.3 42.5 0.1 7.3 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 139.4 0.0 0.0 1.1 0.0 0.0 0.7 17.3 1.5 1.9 0.1 0.6 9.3 2.3 10.9 0.9 4.6 0.4 5.9 9.6 13.0 0.3 2.3 0.8 74.1 2.5 0.0 0.0 1.5 64.1 1.6 21.5 11.2 22.0 0.0 82.1 6.9 0.0 9.8 0.2 0.5 6.2 273.3 6.6 0.0 0.0 2.2 0.0 57.8 40.6 0.0 5.7 2.5 0.0 2.9 53.2 8.9 0.0 8.1 9.9 2.0 3.1 1.2 0.5 4.1 10.7 0.0 0.0 0.2 0.0 0.0 0.5 0.3 0.6 13.8 1.2 0.1 40.0 372.4 125.7 1.6 0.0 0.0 17.4 11.1 0.2 0.5 0.1 0.3 126.0 2.5 0.1 12.6 33.6 MMEL1 "MMEL2, NEPII, NL1, NL2, SEP" ENSG00000142606 "Membrane metalloendopeptidase like 1" Q495T6 1 2590639-2633016 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 24.6" "Cell type enhanced" "Detected in many" "Early spermatids: 131.2;Late spermatids: 36.1;Paneth cells: 54.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 14.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007876, HPA008205, CAB020786" Uncertain "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "CAB020786: , HPA007876: AB_1854012, HPA008205: AB_1854011" "unprognostic (5.80e-2)" "unprognostic (4.61e-2)" "unprognostic (1.87e-1)" "unprognostic (4.27e-2)" "unprognostic (1.33e-1)" "unprognostic (2.71e-2)" "unprognostic (1.45e-1)" "unprognostic (7.96e-2)" "unprognostic (1.36e-2)" "unprognostic (2.37e-1)" "unprognostic (4.54e-3)" "unprognostic (2.44e-2)" "unprognostic (4.79e-2)" "unprognostic (3.18e-1)" "unprognostic (2.82e-1)" "unprognostic (2.18e-3)" "unprognostic (7.01e-4)" 2.9 1.4 0.6 0.0 0.6 0.0 3.0 0.5 0.9 3.2 0.4 3.7 2.6 0.7 0.9 4.8 2.9 0.0 0.5 0.5 0.8 3.7 0.5 2.8 0.0 1.0 1.0 0.4 2.0 0.6 0.7 0.0 0.8 6.5 0.3 0.1 1.6 0.3 0.2 0.7 4.2 0.0 0.7 2.5 8.2 24.6 0.7 0.0 1.1 0.0 0.0 3.1 3.2 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.3 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.1 0.0 14.2 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 1.0 4.7 0.3 2.6 0.2 0.4 1.0 0.4 0.7 0.0 2.7 1.3 0.6 1.8 3.6 0.1 4.2 1.7 0.6 0.6 0.5 0.9 0.5 0.8 1.0 1.0 0.8 0.7 0.7 0.6 5.9 0.0 0.0 0.3 0.4 0.0 5.2 5.2 1.2 0.0 10.3 8.9 1.1 20.0 10.2 18.4 0.0 0.0 0.3 12.1 0.0 9.4 131.2 7.1 0.5 2.3 1.2 2.5 0.1 3.4 0.0 1.3 8.6 7.3 0.0 0.0 1.4 0.2 1.2 0.0 0.2 16.5 2.0 1.0 0.2 36.1 1.8 2.4 0.0 0.0 0.9 0.5 0.0 0.5 0.0 4.0 54.9 1.2 0.2 6.7 20.8 0.1 8.8 0.2 0.0 0.0 0.6 0.6 1.1 0.6 0.0 0.0 0.8 0.4 9.7 12.6 MMGT1 "EMC5, TMEM32" ENSG00000169446 "Membrane magnesium transporter 1" Q8N4V1 X 135960588-135974029 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032037 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" "HPA032037: AB_10670705" "prognostic unfavorable (8.54e-4)" "unprognostic (2.18e-2)" "unprognostic (2.19e-1)" "unprognostic (1.90e-2)" "unprognostic (2.23e-3)" "unprognostic (8.94e-3)" "unprognostic (2.61e-2)" "unprognostic (1.34e-1)" "unprognostic (2.73e-1)" "unprognostic (3.87e-1)" "unprognostic (2.35e-1)" "unprognostic (2.38e-1)" "prognostic favorable (1.94e-5)" "unprognostic (6.08e-2)" "unprognostic (2.94e-2)" "unprognostic (1.05e-1)" "unprognostic (1.29e-2)" 17.5 11.0 8.8 12.2 9.3 26.3 12.4 8.3 9.1 15.3 6.2 15.2 11.3 16.3 11.4 17.1 13.7 15.9 18.1 7.9 14.3 17.2 9.0 13.1 11.3 9.3 9.9 14.1 13.4 17.3 9.3 12.4 9.2 12.1 15.1 13.3 14.2 11.6 17.4 10.6 12.8 16.5 8.9 10.3 12.2 4.3 11.0 14.6 24.2 20.0 12.4 15.2 9.6 9.8 28.6 12.9 16.5 25.5 29.6 32.6 21.9 33.1 31.1 27.1 53.2 15.1 43.3 18.7 61.0 32.2 30.3 23.7 45.0 22.9 39.3 22.3 26.3 13.3 16.5 8.9 22.8 26.5 18.9 27.3 36.1 46.1 29.2 27.0 20.1 21.5 18.1 38.9 26.8 20.8 21.2 12.6 12.4 30.9 27.2 17.7 27.6 36.7 20.2 14.2 23.2 23.8 18.2 17.6 41.2 23.5 17.7 12.9 21.9 32.4 18.6 50.7 42.7 23.1 41.4 22.8 28.5 35.6 37.5 12.9 12.1 7.5 8.2 11.8 10.1 7.0 10.5 9.7 11.1 5.7 10.5 9.1 6.6 9.8 13.0 6.7 13.4 10.0 8.8 9.3 8.3 9.1 7.9 14.3 9.3 9.9 9.2 8.9 11.0 9.8 17.6 12.8 13.7 5.5 25.3 22.2 19.8 12.0 37.0 16.6 14.8 15.1 25.3 11.5 12.0 14.7 8.4 7.9 17.9 19.4 7.9 12.1 0.3 12.3 24.4 15.5 25.8 18.7 5.9 12.4 12.6 20.1 13.3 17.1 14.0 3.9 15.7 10.2 14.1 20.2 5.6 15.1 18.3 33.7 23.2 0.6 13.7 29.7 26.6 1.0 25.1 17.9 7.2 6.0 7.4 13.7 9.2 19.2 28.7 23.6 17.0 13.4 9.2 12.6 6.6 20.6 25.0 2.2 7.5 35.6 24.7 11.5 22.3 4.4 17.9 19.6 MMP1 CLG ENSG00000196611 "Matrix metallopeptidase 1" P03956 11 102789401-102798160 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation, Host-virus interaction" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 75.7;stomach 1: 47.6;urinary bladder: 52.2" "Cell type enriched" "Detected in many" 10 "Pancreatic endocrine cells: 2239.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 344.2" "Region enriched" "Detected in single" 7 "cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1139.1;HBF TERT88: 1094.4;HUVEC TERT2: 2954.4;WM-115: 1454.1" "Not detected" "Not detected" HPA004920 Approved Vesicles "Secreted to extracellular matrix" NA NA 7730000 55000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "HPA004920: AB_2667293" "unprognostic (4.11e-3)" "prognostic unfavorable (4.66e-4)" "unprognostic (4.20e-3)" "unprognostic (1.19e-3)" "unprognostic (6.46e-2)" "unprognostic (6.50e-2)" "prognostic unfavorable (4.22e-6)" "unprognostic (7.83e-3)" "unprognostic (2.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.86e-10)" "unprognostic (1.67e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (5.11e-2)" 0.3 0.1 0.0 26.7 0.0 0.3 0.2 0.0 1.3 0.1 0.0 6.1 7.9 10.7 0.0 4.2 0.1 75.7 0.4 0.0 0.1 1.0 0.8 6.7 0.1 0.0 0.0 0.0 1.8 0.0 0.1 7.2 0.0 0.4 6.8 0.0 6.9 0.2 0.0 0.6 13.0 1.2 0.0 2.1 47.6 0.1 0.1 0.3 0.2 0.0 1.7 52.2 0.2 0.0 0.0 0.0 0.0 1.0 0.0 1.1 0.0 517.1 1139.1 456.6 118.2 9.1 1.0 0.0 5.2 275.5 175.2 4.6 0.0 160.0 1094.4 0.0 1.0 0.0 0.0 0.0 2.9 0.0 0.5 0.3 0.8 470.1 39.6 0.1 2954.4 0.0 1.5 0.5 0.3 0.0 0.0 0.0 0.4 189.3 20.8 0.0 0.1 0.0 0.7 2.2 0.0 0.1 4.8 0.0 1.6 0.1 0.5 0.0 155.0 374.1 0.6 16.8 1.3 0.1 0.0 0.0 8.8 0.0 1454.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.3 3.2 2.6 0.0 0.2 2.3 22.4 90.4 0.0 0.0 0.0 0.0 0.1 30.0 15.8 3.7 0.0 0.0 0.0 0.2 0.0 143.7 0.0 0.1 0.2 113.2 0.0 0.0 0.1 204.8 0.1 11.5 25.5 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.0 1.9 0.4 0.0 0.0 15.5 0.0 0.0 4.2 0.0 0.0 0.0 0.0 2239.5 1.2 0.0 0.0 30.9 0.7 0.2 1.3 0.0 0.0 1.8 10.5 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 44.3 MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770502-102780628 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "endometrium 1: 265.4" "Cell type enriched" "Detected in some" 38 "Basal respiratory cells: 3913.2" "Group enriched" "Detected in many" 4 "cervical cancer: 47.8;head and neck cancer: 102.2;lung cancer: 42.3" "Region enhanced" "Detected in single" "thalamus: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 11.8;HUVEC TERT2: 15.1;SCLC-21H: 4.7" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 765000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB002159: AB_564103" "unprognostic (8.76e-2)" "unprognostic (3.38e-1)" "unprognostic (1.98e-3)" "unprognostic (2.72e-3)" "unprognostic (7.17e-3)" "unprognostic (1.52e-2)" "unprognostic (5.67e-8)" "unprognostic (2.08e-3)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (1.67e-2)" "unprognostic (2.67e-1)" "unprognostic (6.99e-5)" "unprognostic (2.66e-2)" "unprognostic (7.98e-2)" "unprognostic (5.46e-2)" "prognostic favorable (7.12e-4)" 0.1 0.0 0.1 7.7 0.0 0.1 0.1 0.0 0.8 1.2 0.0 0.4 1.1 265.4 0.0 0.2 0.0 1.3 0.0 0.2 0.3 0.1 1.0 2.0 0.1 0.1 0.3 0.2 0.2 0.0 0.0 1.3 0.3 1.4 0.2 0.0 1.6 0.0 0.0 0.1 0.8 0.2 0.0 0.0 2.9 0.5 1.9 0.6 0.0 0.2 0.7 4.4 3.2 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.2 11.8 0.6 0.1 0.1 0.3 0.0 0.0 3.3 1.8 0.2 2.7 0.0 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.5 0.0 15.1 0.0 0.7 0.0 0.0 0.0 0.0 0.3 2.8 0.5 1.6 0.0 0.0 0.0 0.0 0.6 4.7 0.0 2.4 0.0 0.0 0.8 0.0 0.0 1.9 3.5 1.2 0.4 0.5 0.0 0.0 0.1 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.2 0.3 0.1 0.3 0.3 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.8 51.3 3913.2 0.0 0.0 0.7 0.0 0.1 0.0 85.4 29.5 0.0 0.0 0.0 0.4 0.0 34.0 6.1 6.4 2.5 9.0 0.0 0.0 0.0 14.6 0.0 6.3 0.0 12.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 9.5 1.3 0.0 0.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 102.5 0.1 0.0 0.0 42.5 0.0 0.1 29.3 0.0 0.0 0.0 11.7 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 8.2 MMP11 STMY3 ENSG00000099953 "Matrix metallopeptidase 11" P24347 22 23768226-23784316 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 64.8;endometrium 1: 142.8;placenta: 39.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 84.9;Extravillous trophoblasts: 37.6;Granulosa cells: 61.9;Smooth muscle cells: 35.8" "Cancer enhanced" "Detected in all" "pancreatic cancer: 119.1" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 4.4" "Cell line enhanced" "Detected in many" "AN3-CA: 38.4;hTERT-RPE1: 19.7;REH: 16.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002593, HPA055204, HPA068864" Approved Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" NA NA 640000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" Cytosol "CAB002593: , HPA055204: , HPA068864: AB_2686051" "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "unprognostic (1.83e-1)" "unprognostic (1.84e-3)" "unprognostic (2.77e-2)" "unprognostic (6.73e-2)" "unprognostic (2.14e-2)" "unprognostic (5.15e-1)" "unprognostic (2.73e-2)" "unprognostic (2.20e-1)" "unprognostic (1.89e-3)" "unprognostic (7.04e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (8.05e-2)" "unprognostic (6.78e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-2)" 3.3 1.6 0.4 1.4 0.3 0.5 2.2 0.3 1.2 64.8 0.3 3.9 6.8 142.8 0.1 1.0 5.7 6.8 7.2 0.3 0.4 2.5 0.6 1.4 3.9 0.4 0.4 12.5 1.3 3.3 0.5 39.6 0.4 1.9 3.5 0.0 5.3 1.5 0.9 3.8 6.0 9.4 0.4 1.4 2.6 6.7 0.4 3.1 1.3 0.9 1.7 2.9 3.6 0.4 0.3 0.0 4.8 38.4 5.7 8.3 0.1 0.6 10.4 1.3 0.8 0.4 1.3 1.3 5.1 2.8 1.8 0.2 2.2 0.0 0.4 0.0 0.8 0.0 0.0 2.2 4.2 0.0 0.0 5.4 0.9 1.1 0.1 19.7 6.0 0.4 0.6 0.0 1.4 0.3 0.1 0.1 1.4 1.2 0.2 16.6 0.0 0.4 0.7 0.0 6.0 10.3 3.9 0.6 0.0 5.9 3.6 0.0 2.7 0.6 0.0 1.6 0.1 0.1 0.2 5.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.4 0.3 0.3 1.2 0.3 0.4 0.4 0.4 0.4 0.4 0.4 0.4 1.2 0.0 2.5 0.3 3.4 1.0 0.8 0.8 0.6 0.4 1.9 0.5 6.1 1.5 0.1 0.0 0.0 0.7 1.8 0.4 1.9 8.6 10.3 4.4 84.9 0.9 1.8 0.0 0.2 0.7 37.6 8.4 1.5 4.1 1.3 61.9 1.1 0.0 0.8 0.0 0.4 1.3 2.0 0.0 1.1 10.5 0.6 1.0 1.8 1.0 0.0 0.3 0.0 0.0 0.2 1.4 0.2 0.4 0.2 0.5 0.1 2.2 0.8 0.5 0.0 2.7 35.8 3.1 5.5 0.5 0.6 18.6 2.0 5.7 1.0 0.3 MMP12 HME ENSG00000262406 "Matrix metallopeptidase 12" P39900 11 102862736-102874982 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.7;lymphoid tissue: 40.4;urinary bladder: 16.0" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 303.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "BJ: 3.3;fHDF/TERT166: 11.4;hTEC/SVTERT24-B: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.69e-2)" "unprognostic (7.31e-2)" "unprognostic (1.52e-2)" "unprognostic (1.52e-3)" "unprognostic (5.45e-2)" "unprognostic (3.05e-6)" "unprognostic (1.08e-2)" "unprognostic (4.66e-2)" "unprognostic (1.73e-1)" "unprognostic (6.92e-2)" 0.5 0.0 0.0 40.4 0.1 0.0 0.4 0.0 0.0 0.1 0.0 13.5 6.8 0.6 0.0 0.4 0.0 2.6 0.0 0.0 0.3 0.9 0.1 0.6 7.0 0.1 0.1 0.0 0.1 0.0 0.0 7.4 0.1 1.3 15.7 0.0 2.4 0.0 0.0 0.5 7.8 2.2 0.1 3.7 3.5 0.0 0.1 3.9 0.0 0.0 19.4 16.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 11.4 0.1 0.4 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 3.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 18.6 303.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.5 0.1 0.0 0.0 2.2 MMP13 CLG3 ENSG00000137745 "Matrix metallopeptidase 13" P45452 11 102942995-102955732 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "urinary bladder: 12.9" "Cell type enriched" "Detected in some" 12 "Basal respiratory cells: 426.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 70.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 17.9;PC-3: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" CAB002742 Supported "Secreted to extracellular matrix" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB002742: " "unprognostic (8.98e-3)" "unprognostic (1.54e-1)" "unprognostic (4.75e-2)" "unprognostic (4.57e-2)" "unprognostic (3.05e-2)" "unprognostic (1.59e-3)" "unprognostic (1.32e-1)" "unprognostic (6.35e-3)" "unprognostic (1.69e-1)" "unprognostic (7.55e-3)" "unprognostic (2.24e-1)" "unprognostic (1.73e-8)" "unprognostic (2.12e-2)" "unprognostic (3.14e-1)" "unprognostic (4.14e-2)" "unprognostic (4.33e-2)" 0.1 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 12.9 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 17.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 0.0 6.7 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 2.4 1.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 426.0 0.0 0.0 0.0 0.0 0.2 0.0 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 6.8 0.0 0.0 0.0 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.8 MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 244.0;Pancreatic endocrine cells: 144.7;Syncytiotrophoblasts: 122.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 923.8;HHSteC: 794.2;HSkMC: 887.0;hTERT-RPE1: 925.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 1400000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: AB_2681484" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" 151.5 31.7 5.6 59.9 5.0 1.6 101.5 5.7 7.5 181.3 61.8 77.2 39.5 167.3 19.0 92.1 82.1 148.2 41.3 6.6 7.2 35.9 13.2 91.8 24.8 11.9 8.4 90.2 36.0 65.3 14.2 118.9 9.2 59.9 36.6 9.6 78.1 45.5 18.8 127.5 69.4 106.0 7.3 30.8 57.7 11.7 13.2 13.0 50.0 16.1 30.8 103.9 111.1 10.6 90.6 1.2 26.3 2.0 923.8 651.6 455.9 270.1 606.4 93.3 158.5 21.3 337.4 0.9 146.4 301.9 24.6 216.3 0.3 262.2 99.7 1.1 0.6 37.2 1.7 5.0 794.2 0.4 1.3 887.0 148.7 334.7 288.3 925.5 492.9 0.6 0.8 2.1 185.1 0.7 0.4 79.4 14.7 17.7 52.4 2.1 96.0 0.2 61.4 148.1 0.3 0.6 187.3 0.3 574.2 104.4 1.0 79.5 436.8 724.9 53.7 198.2 329.6 0.8 1.6 1.1 410.9 0.6 396.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 5.0 5.7 7.5 6.6 7.2 11.9 8.4 9.2 7.3 13.2 10.6 13.9 12.8 3.0 2.0 3.4 34.0 23.4 105.4 39.3 0.0 14.1 17.5 4.7 50.1 42.2 7.3 0.0 105.6 0.3 19.9 11.7 63.0 0.4 16.1 81.6 35.2 7.8 0.0 0.0 28.7 244.0 84.0 25.5 14.8 3.8 9.3 32.9 2.7 89.5 0.0 0.0 24.5 34.6 20.2 32.7 2.4 72.1 38.0 37.4 4.7 21.5 14.3 0.0 0.5 0.1 144.7 33.0 54.9 0.3 21.8 19.9 11.7 46.8 0.8 39.5 11.1 73.9 0.8 0.8 33.7 34.2 122.7 2.5 15.6 18.6 37.9 MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 2402.1" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.4;HUVEC TERT2: 12.8;SH-SY5Y: 16.2;U-138 MG: 13.7;WM-115: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" 0.7 0.3 4.6 0.3 5.8 0.0 1.8 2.2 5.4 1.7 0.0 0.8 0.1 1.6 0.6 0.4 0.6 2.6 0.8 5.1 3.9 0.1 0.1 0.2 0.2 1.0 1.5 1.0 0.6 0.2 0.5 1.0 1.3 0.9 0.4 0.4 0.3 0.7 0.1 0.2 0.3 1.3 1.4 0.4 0.3 0.4 3.0 0.4 1.0 0.5 0.2 0.9 0.5 3.3 0.0 0.2 7.9 29.4 1.0 2.0 0.0 10.9 1.6 3.0 1.8 0.0 0.1 0.0 0.0 4.9 1.8 0.0 5.8 0.0 3.7 0.0 3.4 0.0 0.0 0.0 2.4 0.0 0.5 1.4 0.0 4.4 1.3 5.4 12.8 0.1 0.0 1.1 1.7 0.0 0.0 0.0 1.7 0.0 3.0 0.3 0.6 0.0 0.6 0.1 0.2 16.2 0.0 0.0 0.2 2.2 1.1 0.0 7.1 13.7 7.7 0.2 4.2 0.0 0.0 0.0 5.7 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 2.2 5.4 5.1 3.9 1.0 1.5 1.3 1.4 3.0 3.3 2.2 0.0 0.0 20.5 0.1 1.1 0.0 0.0 0.6 4.4 0.8 1.4 1.0 0.0 0.0 0.0 2.1 0.1 0.1 0.0 1.9 0.0 6.5 0.5 15.9 5.2 0.0 0.0 443.4 0.0 0.1 16.0 0.0 0.4 0.0 1.9 1.4 0.0 0.4 1.7 300.3 0.0 0.0 0.0 1.6 6.5 0.9 0.4 1.8 10.3 0.0 3.0 0.0 2402.1 13.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.7 2.9 0.0 1.1 0.2 0.1 0.0 0.2 3.4 0.0 0.1 MMP17 MT4-MMP ENSG00000198598 "Matrix metallopeptidase 17" Q9ULZ9 12 131828393-131851783 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.2" "Group enriched" "Detected in many" 5 "Excitatory neurons: 47.0;Inhibitory neurons: 14.3;Melanocytes: 28.4;Oligodendrocyte precursor cells: 26.7" "Cancer enriched" "Detected in many" 10 "melanoma: 29.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "REH: 29.6;SK-MEL-30: 60.4;WM-115: 87.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (9.11e-2)" "unprognostic (1.27e-2)" "unprognostic (1.69e-2)" "unprognostic (3.71e-3)" "unprognostic (5.62e-2)" "unprognostic (1.85e-2)" "unprognostic (8.90e-3)" "unprognostic (2.14e-2)" "unprognostic (2.60e-1)" "unprognostic (2.66e-4)" "unprognostic (7.68e-2)" "unprognostic (5.88e-2)" "unprognostic (9.26e-10)" "unprognostic (1.15e-2)" "unprognostic (2.65e-1)" "unprognostic (1.21e-3)" "unprognostic (2.81e-2)" 3.9 0.8 9.9 1.2 16.6 0.9 4.0 0.0 37.2 10.8 0.0 6.4 0.3 3.7 0.0 1.7 2.4 1.0 2.2 31.7 9.2 1.0 1.0 2.0 0.9 0.0 0.2 11.6 2.0 0.1 1.5 0.1 0.3 2.9 0.1 0.1 3.1 0.5 0.9 4.7 2.7 0.3 0.0 1.7 1.6 3.2 6.3 0.0 1.7 0.0 0.2 2.7 4.7 8.8 0.3 11.5 0.0 0.5 2.3 2.9 0.1 7.2 7.9 2.1 3.3 0.0 1.4 0.0 5.2 1.8 1.4 3.8 1.3 1.5 0.0 0.0 0.7 1.1 3.8 0.0 3.6 0.0 7.2 2.7 1.2 2.4 0.0 0.5 4.0 0.0 2.0 0.0 1.0 8.3 0.0 11.5 4.6 1.6 7.3 29.6 0.0 3.9 0.0 0.0 3.7 2.0 1.0 0.2 60.4 0.5 7.4 12.8 5.8 0.7 0.9 6.3 0.6 0.0 0.0 0.0 2.4 0.3 87.5 0.0 0.4 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 9.9 16.6 0.0 37.2 31.7 9.2 0.0 0.2 0.3 0.0 6.3 8.8 0.6 0.0 0.0 2.9 2.3 2.5 0.1 1.7 0.6 1.0 2.3 1.8 1.2 1.5 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 5.4 0.5 0.0 0.0 47.0 0.2 0.2 5.4 0.0 0.4 0.0 0.7 1.1 0.0 0.6 3.3 14.3 0.0 2.0 2.6 1.0 0.4 0.9 3.4 28.4 3.7 2.4 0.1 0.0 26.7 2.9 0.0 0.0 1.9 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.8 1.4 0.4 0.4 0.1 1.1 0.0 0.2 5.3 0.0 0.2 MMP19 "MMP18, RASI-1" ENSG00000123342 "Matrix metallopeptidase 19" Q99542 12 55835433-55842966 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Angiogenesis, Collagen degradation, Differentiation" "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 58.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.4;Fibroblasts: 52.8;Hofbauer cells: 30.8;Kupffer cells: 35.7;Langerhans cells: 100.7;Macrophages: 61.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "thalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 75.6" "Region enriched" "Detected in many" 5 "olfactory bulb: 7.2" "Low region specificity" "Detected in all" HPA070804 Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 2100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "HPA070804: AB_2686315" "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (2.28e-2)" "unprognostic (2.42e-1)" "unprognostic (4.77e-3)" "unprognostic (4.77e-3)" "unprognostic (2.01e-2)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (8.56e-9)" "unprognostic (5.06e-3)" "unprognostic (1.28e-3)" "unprognostic (2.73e-2)" "unprognostic (4.00e-2)" 58.5 3.6 0.0 11.4 0.1 0.7 18.3 0.0 0.3 10.4 0.5 7.3 1.2 20.7 0.5 2.3 17.2 25.6 8.8 0.1 0.1 5.7 2.7 25.4 2.8 0.1 0.1 11.9 7.2 0.5 0.8 10.8 0.2 3.3 3.3 0.1 3.1 2.3 0.9 5.5 8.7 8.7 0.1 27.4 9.6 0.4 1.3 2.9 4.4 0.6 6.9 9.6 6.2 0.1 1.5 0.0 0.2 0.0 7.8 12.4 75.6 10.1 10.6 3.9 4.4 0.6 0.6 0.0 0.0 12.8 0.3 0.0 0.0 3.0 4.0 0.8 0.0 0.0 0.3 0.1 6.5 0.0 0.6 12.1 0.4 1.9 2.4 6.2 0.7 0.0 0.2 0.1 11.2 0.0 0.0 0.2 0.3 0.0 0.2 0.0 2.8 0.0 1.7 4.7 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.2 15.7 2.2 5.0 0.2 0.3 0.1 0.0 0.0 8.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.2 0.1 1.3 0.1 2.8 0.0 4.6 0.7 1.3 7.1 0.3 1.9 0.6 0.4 0.3 0.3 0.7 11.5 3.3 0.0 4.2 18.6 0.7 0.0 0.0 0.3 0.5 2.4 20.8 1.5 0.0 0.0 0.2 0.5 54.4 52.8 1.1 1.7 2.5 0.4 3.6 0.7 30.8 0.0 0.2 0.1 0.0 35.7 100.7 0.9 5.9 61.2 12.4 1.9 22.5 0.4 0.0 0.0 0.3 0.1 0.0 5.3 1.0 0.3 0.0 0.1 1.5 1.7 0.0 3.8 7.6 0.2 0.2 1.0 4.3 18.7 0.9 0.2 0.0 0.4 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MMP20 ENSG00000137674 "Matrix metallopeptidase 20" O60882 11 102576832-102625332 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Amelogenesis imperfecta" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 7 "Early spermatids: 91.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "OE19: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 21: OE19 - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (4.62e-3)" "unprognostic (2.61e-2)" "unprognostic (1.68e-3)" "unprognostic (1.75e-1)" "unprognostic (2.13e-1)" "unprognostic (3.06e-1)" "unprognostic (2.97e-2)" "unprognostic (6.75e-2)" "unprognostic (9.58e-5)" "unprognostic (6.10e-2)" "unprognostic (2.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 12.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 6.6 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.4 MMP21 ENSG00000154485 "Matrix metallopeptidase 21" Q8N119 10 125753580-125775821 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" Heterotaxy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "epididymis: 53.9" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Granulosa cells: 1.4;Microglial cells: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.32e-2)" "unprognostic (1.28e-1)" "unprognostic (8.51e-2)" "unprognostic (2.19e-2)" "unprognostic (4.02e-2)" "unprognostic (2.21e-2)" "unprognostic (4.22e-3)" "unprognostic (1.01e-1)" "unprognostic (2.12e-1)" "unprognostic (1.48e-1)" "unprognostic (2.89e-2)" "unprognostic (3.62e-2)" "unprognostic (9.70e-8)" "unprognostic (1.30e-2)" "unprognostic (7.69e-2)" "unprognostic (7.00e-2)" "unprognostic (2.18e-1)" 0.2 0.3 0.4 0.6 0.7 0.7 0.2 1.7 0.7 0.2 0.2 0.2 0.5 0.5 53.9 0.5 0.4 0.7 0.8 0.5 0.4 0.1 0.3 0.2 1.0 0.3 0.3 3.7 0.7 0.0 0.1 0.1 0.2 0.5 0.1 1.8 1.2 0.2 0.3 1.2 0.4 0.2 0.1 0.6 0.4 1.0 0.5 0.0 0.5 0.0 0.2 0.2 0.0 0.9 0.4 0.2 0.6 0.4 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.4 0.1 0.9 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.2 0.2 0.3 0.3 0.0 0.3 0.2 0.1 0.1 0.0 0.3 0.1 0.2 0.2 0.0 0.0 0.2 0.1 0.1 0.2 0.5 0.2 0.2 0.3 0.5 0.4 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 1.7 0.7 0.5 0.4 0.3 0.3 0.2 0.1 0.5 0.9 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 1.4 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.5 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 MMP23B "MIFR, MIFR-1, MMP22" ENSG00000189409 "Matrix metallopeptidase 23B" O75900 1 1632163-1635263 "Enzymes, Predicted intracellular proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 90.5;Leydig cells: 98.2;NK-cells: 64.9;Peritubular cells: 177.9" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 11.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.3" "Cell line enhanced" "Detected in some" "HHSteC: 4.4;NTERA-2: 2.7;PC-3: 1.9;U-266/70: 3.9" "Region enriched" "Detected in some" 5 "cerebellum: 7.8" "Low region specificity" "Detected in some" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.19e-2)" "unprognostic (6.31e-2)" "unprognostic (6.70e-3)" "unprognostic (1.29e-1)" "unprognostic (3.99e-2)" "unprognostic (9.31e-2)" "unprognostic (6.94e-2)" "unprognostic (1.20e-1)" "unprognostic (8.06e-2)" "unprognostic (8.37e-2)" "unprognostic (2.22e-1)" "unprognostic (2.33e-1)" "unprognostic (2.26e-11)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.44e-2)" "unprognostic (6.66e-2)" 7.1 2.8 0.4 0.3 0.5 1.3 4.1 0.1 1.0 16.7 0.0 5.0 1.9 15.4 0.0 2.8 11.0 2.9 15.0 0.3 0.0 3.2 3.3 14.3 1.1 0.4 0.0 29.9 1.6 0.0 5.7 2.8 0.1 11.8 0.1 0.1 1.0 1.1 0.5 3.1 3.4 1.2 0.0 3.0 4.3 5.2 0.1 0.0 2.4 0.0 0.1 11.9 10.9 0.2 0.6 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.4 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.5 0.2 1.2 4.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.4 0.0 0.2 2.7 0.0 1.9 0.9 0.0 1.1 0.0 0.0 0.4 0.2 0.3 0.0 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.3 0.0 3.9 0.2 1.1 0.0 0.2 0.1 0.0 0.2 0.0 1.5 0.0 0.9 0.0 0.3 1.0 0.0 0.1 0.0 0.7 0.1 2.2 0.1 11.3 0.3 1.7 0.4 0.5 0.1 1.0 0.3 0.0 0.4 0.0 0.1 0.0 0.1 0.2 2.2 0.0 0.5 1.0 1.1 13.4 0.8 0.7 0.6 1.3 1.7 1.5 9.6 1.5 0.4 1.8 0.0 4.0 27.4 3.0 0.0 1.2 1.0 4.0 3.5 2.2 3.0 2.7 0.3 0.5 2.2 90.5 4.6 1.0 0.0 1.4 12.1 1.0 5.7 3.3 0.6 1.9 4.1 1.0 18.5 6.2 98.2 1.3 19.6 0.0 1.2 0.5 64.9 0.0 0.2 4.3 0.9 177.9 4.3 0.5 2.7 1.0 0.5 7.7 0.0 0.7 5.3 2.1 10.5 0.7 15.8 10.3 8.1 2.1 1.7 0.9 MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046062-3060726 "Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.1;lymphoid tissue: 81.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6.7;Langerhans cells: 5.8;monocytes: 15.0" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "basophil: 18.3;neutrophil: 20.3" "Lineage enriched" "Detected in single" 39 "granulocytes: 20.3" "Cell line enriched" "Detected in some" 15 "HMC-1: 102.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025177, HPA055640" Uncertain Supported "Plasma membrane" "Secreted to blood" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "CAB025177: , HPA055640: " "unprognostic (4.51e-3)" "unprognostic (9.28e-3)" "unprognostic (7.57e-2)" "unprognostic (2.95e-3)" "unprognostic (2.26e-1)" "prognostic favorable (1.09e-5)" "unprognostic (1.36e-1)" "unprognostic (7.39e-3)" "unprognostic (7.63e-3)" "unprognostic (2.29e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.37e-3)" "unprognostic (1.17e-2)" "unprognostic (8.30e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" 5.8 0.4 0.5 15.1 0.4 33.1 1.4 0.3 1.6 0.7 0.6 1.7 1.1 0.5 0.1 1.3 6.2 1.1 2.4 0.3 0.3 1.4 2.9 14.4 2.6 0.6 0.5 0.4 1.2 0.2 0.8 1.0 0.6 1.0 1.4 0.0 1.2 0.1 0.5 0.7 3.5 0.9 0.3 81.8 1.9 0.4 0.7 1.4 1.2 3.5 1.9 2.2 0.9 0.3 0.0 0.0 1.2 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.7 0.1 0.0 6.7 0.5 0.0 0.0 0.0 0.0 0.2 102.2 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.7 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.3 7.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 18.3 0.2 4.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 20.3 0.5 0.0 0.4 0.2 0.0 0.5 0.4 0.3 1.6 0.3 0.3 0.6 0.5 0.6 0.3 0.7 0.3 1.0 3.2 6.7 0.0 0.7 0.4 0.4 0.2 0.0 0.8 2.0 1.3 1.0 0.0 0.8 1.8 0.0 0.0 1.8 0.2 0.0 0.4 0.0 1.2 1.2 1.0 0.0 2.7 1.6 0.6 0.2 0.6 1.1 3.8 1.3 0.2 0.0 0.3 0.1 0.0 1.9 0.2 0.0 3.5 5.8 0.0 0.0 3.3 0.0 1.0 15.0 0.3 3.1 1.5 0.5 1.3 0.0 0.7 0.8 0.4 1.2 0.2 0.1 0.0 0.0 0.7 0.9 0.1 0.2 0.6 0.3 0.0 4.0 0.1 0.3 0.3 MMP26 "endometase, MGC126590, MGC126592" ENSG00000167346 "Matrix metallopeptidase 26" Q9NRE1 11 4704927-4992429 "Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "endometrium 1: 13.1" "Group enriched" "Detected in some" 7 "Endometrial ciliated cells: 44.8;Glandular and luminal cells: 171.1" "Cancer enriched" "Detected in some" 4 "endometrial cancer: 8.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 44: Endometrium - Transcription" "unprognostic (4.21e-3)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 44.8 14.6 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 171.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 MMP27 ENSG00000137675 "Matrix metallopeptidase 27" Q9H306 11 102691487-102705769 "Enzymes, Predicted intracellular proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 4.7;salivary gland: 1.9;skin 1: 2.4" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Fibroblasts: 4.2;Langerhans cells: 1.8;Suprabasal keratinocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA069097 Approved "Intracellular and membrane" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 50: Fibroblasts - ECM organization" "HPA069097: AB_2686085" "unprognostic (3.99e-2)" "unprognostic (2.37e-4)" "unprognostic (1.25e-3)" "unprognostic (1.63e-1)" "unprognostic (4.60e-1)" 1.2 0.0 0.0 0.0 0.0 1.3 4.7 0.0 0.0 0.2 0.0 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.9 0.0 0.4 2.4 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Basal respiratory cells: 56.8;Distal enterocytes: 82.0;Paneth cells: 46.2;Proximal enterocytes: 47.2;Urothelial cells: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 6.3;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 86.9;hTCEpi: 38.3;OE19: 41.7;RT4: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057288, HPA057890" Approved "Nucleoplasm,Focal adhesion sites" "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA057288: , HPA057890: " "unprognostic (7.99e-3)" "unprognostic (3.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.28e-6)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" 14.7 2.0 18.7 0.5 18.1 0.2 8.3 12.1 18.8 4.1 11.9 17.5 1.8 5.2 2.1 13.5 6.1 1.4 3.8 16.2 15.6 1.9 0.3 14.1 0.2 15.2 17.8 1.1 0.8 0.1 1.3 2.0 12.9 5.0 10.5 3.0 2.5 3.5 1.8 23.7 10.2 4.1 14.4 1.1 8.8 22.3 19.3 0.3 5.9 2.4 3.2 16.3 7.6 13.9 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.1 1.5 0.0 0.1 86.9 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.0 4.3 0.0 0.0 1.2 38.3 0.0 3.1 0.7 0.3 0.3 0.0 0.2 0.0 0.3 0.1 0.3 0.0 41.7 0.1 0.8 0.0 0.0 0.0 15.7 0.2 0.7 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.6 0.2 1.0 0.0 0.4 6.3 3.7 0.0 0.9 0.2 0.9 0.0 0.4 18.7 18.1 12.1 18.8 16.2 15.6 15.2 17.8 12.9 14.4 19.3 13.9 31.5 28.9 26.5 47.7 0.4 38.5 5.3 56.8 21.1 2.7 1.0 1.5 1.3 7.2 15.2 7.3 0.0 0.0 0.2 82.0 0.0 1.2 6.7 0.1 0.0 16.8 3.6 0.4 2.8 0.4 0.0 4.4 12.2 0.1 0.0 0.0 17.9 0.0 0.1 1.7 4.8 32.9 2.0 0.0 1.8 13.4 1.2 0.5 3.6 10.3 0.4 9.4 1.0 1.0 0.6 16.7 46.2 3.0 0.1 8.6 47.2 0.8 4.5 0.5 6.6 0.7 5.5 1.1 3.7 34.9 33.1 0.0 1.0 0.1 21.5 43.9 MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843609 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.7;salivary gland: 286.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 20.4;Basal respiratory cells: 25.8;Early spermatids: 24.2;Extravillous trophoblasts: 13.4;Fibroblasts: 17.9;Prostatic glandular cells: 11.9;Smooth muscle cells: 10.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Region enriched" "Detected in some" 4 "thalamus: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "BJ: 1545.7;BJ hTERT+: 4229.3;fHDF/TERT166: 1846.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 3.2" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA 2540000 460000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" 90.7 0.1 0.3 20.1 0.4 0.0 36.6 0.2 1.6 0.3 0.1 6.1 2.4 38.1 0.2 0.8 0.2 1.9 0.2 0.4 1.6 0.4 1.6 0.3 0.0 0.4 0.4 0.1 0.3 0.1 0.9 0.4 0.3 2.2 2.3 0.0 286.1 2.2 39.6 63.7 4.5 1.6 0.3 0.0 10.5 0.1 7.3 0.1 2.6 0.4 1.3 13.9 0.5 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1545.7 4229.3 27.0 8.7 0.1 0.2 0.0 0.0 1846.6 96.9 0.0 0.1 0.1 45.1 0.0 0.0 0.0 0.0 1.0 0.7 0.0 0.0 4.6 0.2 122.0 5.3 0.0 0.0 0.0 0.2 0.3 4.7 0.0 0.0 0.0 0.2 0.4 0.9 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.9 0.0 0.3 0.0 140.5 13.1 1.6 0.5 0.0 0.0 0.2 56.8 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.6 0.4 1.6 0.4 0.4 0.3 0.3 7.3 0.3 0.0 3.2 0.0 0.0 0.0 8.4 20.4 25.8 0.0 0.0 0.1 0.1 0.3 4.3 7.6 0.0 0.0 0.1 0.0 0.0 0.0 0.8 24.2 0.0 0.3 0.5 0.0 0.0 0.2 1.4 13.4 17.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.1 0.0 2.2 1.2 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.5 4.0 0.0 0.0 11.9 1.0 0.9 0.1 0.0 0.0 1.8 10.2 0.0 1.8 0.0 3.4 0.3 0.6 0.0 0.8 7.4 MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530750 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 509.9;salivary gland: 267.9;urinary bladder: 211.2" "Cell type enriched" "Detected in many" 8 "Ductal cells: 8176.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 145.9;CAPAN-2: 815.9;EFO-21: 189.8;RPTEC TERT1: 350.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 2810000 35000 "Cluster 5: Breast - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles" "CAB025869: , HPA051358: AB_2681452" "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavorable (2.53e-4)" "prognostic unfavorable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" 3.8 0.1 0.0 2.0 0.0 0.3 168.7 0.0 0.3 13.3 0.0 1.6 0.6 97.4 27.9 21.3 91.2 509.9 0.2 0.0 0.0 140.2 3.4 31.6 1.9 0.0 0.0 0.7 85.2 0.0 0.3 0.8 0.0 54.0 1.0 0.0 267.9 34.9 0.1 32.4 0.6 4.8 0.0 0.2 7.3 0.6 0.4 3.3 0.4 0.0 29.3 211.2 1.7 0.0 0.2 145.9 0.0 0.4 0.0 0.0 0.2 0.0 2.1 0.1 0.1 1.9 815.9 0.0 189.8 0.0 0.0 1.1 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.6 1.0 0.1 0.2 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.5 11.8 0.0 0.0 0.0 0.0 350.1 1.0 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.1 0.0 0.7 3.0 0.0 1.6 0.1 0.6 0.4 1.0 5.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 86.6 43.3 0.0 1.5 1.0 382.2 135.4 1.2 0.0 124.2 93.7 0.7 100.1 401.2 1017.0 0.0 0.7 2.9 1.2 0.0 8176.2 6.1 62.1 3.3 8.8 0.0 0.0 0.0 209.4 0.3 3.4 0.0 124.6 2.5 0.0 0.0 0.0 98.0 0.0 0.0 0.0 38.7 0.6 0.3 10.3 11.8 12.6 0.0 0.0 65.2 0.0 0.0 0.0 0.0 850.9 0.0 0.0 0.1 603.3 0.0 33.9 72.6 0.0 0.0 0.0 31.4 0.1 0.2 17.0 2.4 0.8 3.6 0.0 2.3 840.8 MMP8 CLG1 ENSG00000118113 "Matrix metallopeptidase 8" P22894 11 102711796-102727050 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "bone marrow: 501.1" "Group enriched" "Detected in some" 6 "Hofbauer cells: 4.0;Macrophages: 1.5" "Cancer enriched" "Detected in single" 17 "melanoma: 5.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 1.7" "Cell line enriched" "Detected in some" 8 "WM-115: 70.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021221, HPA021763, HPA022935" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 360000 "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA021221: AB_1854043, HPA021763: , HPA022935: AB_1854044" "unprognostic (3.03e-1)" "unprognostic (8.49e-5)" "unprognostic (1.08e-2)" "unprognostic (3.95e-3)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "unprognostic (7.68e-3)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (6.64e-3)" "unprognostic (2.45e-6)" "unprognostic (2.33e-4)" "unprognostic (1.33e-1)" "unprognostic (4.97e-1)" "unprognostic (2.30e-2)" 0.5 0.0 0.0 0.3 0.1 501.1 0.2 0.1 0.2 0.0 0.2 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.6 4.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.2 0.0 13.8 0.1 0.0 0.6 2.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 376.0;lymphoid tissue: 105.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 260.1;Langerhans cells: 606.0;Macrophages: 230.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.1;thalamus: 4.8" "Immune cell enriched" "Detected in some" 127 "neutrophil: 272.2" "Lineage enriched" "Detected in single" 341 "granulocytes: 272.2" "Cell line enriched" "Detected in some" 13 "NB-4: 360.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" NA NA 43300000 61000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB000348: , CAB068199: AB_2665675, CAB068200: AB_2665676, CAB068201: AB_2665677, HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favorable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" 19.5 0.6 0.5 61.9 0.8 376.0 8.2 0.4 3.1 2.9 0.8 5.7 11.6 1.0 0.0 2.2 2.2 3.0 3.2 0.3 0.9 2.6 3.8 21.1 103.2 0.8 0.5 0.8 1.6 0.1 1.1 2.0 0.7 1.9 3.4 0.6 3.6 0.4 0.7 3.2 12.4 1.9 0.4 105.3 11.3 1.3 4.8 17.0 2.1 0.9 36.5 12.0 1.1 0.2 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.3 0.3 28.8 0.0 0.3 0.4 0.0 1.4 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 4.0 0.0 360.6 0.8 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.6 0.6 0.0 0.6 0.0 3.7 0.3 1.2 0.3 10.3 10.9 0.1 0.3 0.3 0.2 0.2 0.1 0.8 0.2 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 272.2 0.0 0.3 0.0 0.0 0.5 0.5 0.8 0.4 3.1 0.3 0.9 0.8 0.5 0.7 0.4 4.8 0.2 0.7 0.0 5.5 0.0 3.9 34.3 0.1 61.5 0.0 3.8 0.5 2.0 0.4 1.5 0.9 0.0 8.4 1.5 2.0 0.0 0.0 0.8 0.9 0.0 0.1 7.2 0.0 0.0 0.1 1.8 2.4 2.5 0.0 0.1 1.3 0.2 0.0 0.0 260.1 3.3 0.2 0.5 0.0 1.3 606.0 0.3 0.0 230.6 56.9 0.0 2.3 1.2 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.1 0.0 0.3 6.9 5.3 0.0 0.2 45.5 6.7 11.2 0.2 28.1 1.9 3.4 0.3 0.0 0.1 MMRN1 "ECM, EMILIN4, GPIa*, MMRN" ENSG00000138722 "Multimerin 1" Q13201 4 89879532-89954629 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Endothelial cells: 158.0;Hepatic stellate cells: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "NK-cell: 6.3;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 9 "dendritic cells: 2.2;NK-cells: 6.3" "Cell line enriched" "Detected in some" 13 "HUVEC TERT2: 1242.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA035769 Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA035769: AB_10696511" "unprognostic (1.15e-1)" "unprognostic (1.81e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (7.05e-3)" "unprognostic (1.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.88e-1)" "unprognostic (2.12e-1)" "unprognostic (9.71e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.77e-4)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (2.23e-2)" 22.6 3.8 0.8 10.9 0.8 1.8 27.3 0.8 1.1 28.5 1.4 9.9 5.4 15.0 2.8 14.5 23.1 21.1 3.6 0.6 0.9 1.1 8.7 16.1 14.0 1.4 1.4 4.9 3.4 0.5 0.7 40.1 1.2 3.8 14.9 0.5 2.7 4.6 1.1 8.2 13.5 16.8 1.1 0.6 5.2 12.7 1.5 3.7 23.1 6.6 7.6 19.6 9.8 1.1 0.0 0.0 94.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1242.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 6.3 0.0 2.2 0.2 1.2 0.8 0.8 0.8 1.1 0.6 0.9 1.4 1.4 1.2 1.1 1.5 1.1 15.4 0.0 12.0 0.3 2.3 4.2 0.1 0.0 0.0 0.0 0.7 0.1 2.2 0.0 0.6 0.0 0.0 0.0 3.9 0.0 1.9 0.0 17.7 0.3 0.7 158.0 0.0 25.9 0.2 0.0 0.0 1.9 0.0 0.4 2.5 0.1 146.3 2.4 0.6 0.0 0.1 0.0 0.0 5.7 5.9 7.7 0.3 9.1 1.8 21.5 0.7 0.8 2.1 0.0 0.4 0.0 0.0 0.0 5.0 0.4 0.0 0.0 1.5 0.4 0.0 0.3 0.9 15.4 0.0 0.8 4.5 0.0 1.6 0.0 0.0 0.1 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MNX1 "HB9, HLXB9, HOXHB9, SCRA1" ENSG00000130675 "Motor neuron and pancreas homeobox 1" P50219 7 156994051-157010663 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 7.2;pancreas: 16.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 6.6;Enteroendocrine cells: 25.1;Intestinal goblet cells: 19.7;Paneth cells: 7.0;Proximal enterocytes: 7.3;Undifferentiated cells: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 17.2;BEWO: 12.7;EFO-21: 16.2;HEK 293: 13.2;RPMI-8226: 37.6;SCLC-21H: 19.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 39 "spinal cord: 3.9" HPA071717 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Cytosol" "HPA071717: AB_2686437" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.87e-2)" "unprognostic (3.72e-3)" "unprognostic (8.85e-2)" "unprognostic (1.08e-2)" "unprognostic (2.07e-1)" "unprognostic (4.07e-2)" "unprognostic (5.06e-2)" "unprognostic (8.62e-4)" "unprognostic (1.00e-2)" "unprognostic (3.35e-2)" "unprognostic (2.23e-5)" "unprognostic (1.67e-3)" "unprognostic (5.80e-2)" "unprognostic (5.58e-2)" "unprognostic (1.08e-1)" 0.1 0.0 0.5 0.3 0.5 0.1 0.0 0.3 0.6 0.0 0.0 3.7 7.2 0.0 0.0 0.2 0.0 0.8 0.0 0.5 0.2 0.1 0.0 0.0 0.0 1.3 0.3 0.0 16.3 0.0 2.6 0.0 0.9 0.3 3.0 0.0 1.1 0.0 0.0 0.1 6.1 0.0 0.8 0.0 2.2 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.4 5.8 0.0 17.2 0.0 0.0 12.7 0.0 0.0 0.1 0.0 7.6 2.5 1.4 16.2 0.0 0.5 0.3 3.0 2.3 1.3 2.2 13.2 0.0 1.5 3.6 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 0.0 6.1 5.7 2.9 0.0 10.1 0.9 0.2 0.0 1.7 1.1 0.0 2.5 37.6 6.5 0.6 19.3 0.0 2.5 2.2 0.4 0.1 5.4 4.4 0.0 0.0 0.0 0.0 0.0 5.3 2.9 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 0.6 0.5 0.2 1.3 0.3 0.9 0.8 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 1.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.0 4.4 1.3 0.1 0.0 0.1 25.1 0.0 0.0 3.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 19.7 0.0 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 3.1 7.0 0.0 0.4 0.0 7.3 0.1 0.0 0.0 0.0 0.0 0.2 1.8 0.8 0.0 0.0 0.0 0.2 0.0 13.6 0.0 MOXD1 "dJ248E1.1, DKFZP564G202, MOX" ENSG00000079931 "Monooxygenase DBH like 1" Q6UVY6 6 132296055-132401475 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 64.2;smooth muscle: 78.6" "Cell type enhanced" "Detected in many" "Astrocytes: 92.7;Basal squamous epithelial cells: 153.1;Early spermatids: 70.2;Endometrial stromal cells: 57.8;Excitatory neurons: 36.0;Oligodendrocyte precursor cells: 33.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 33 "memory B-cell: 3.1;naive B-cell: 1.7;plasmacytoid DC: 5.1" "Group enriched" "Detected in many" 41 "B-cells: 3.1;dendritic cells: 5.1" "Cell line enhanced" "Detected in many" "ASC diff: 164.8;ASC TERT1: 131.7;BJ: 106.1;fHDF/TERT166: 196.5;HBF TERT88: 120.6;U-2197: 310.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035740 Approved Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "HPA035740: AB_10610141" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (8.05e-2)" "unprognostic (9.87e-3)" "unprognostic (5.62e-2)" "prognostic favorable (7.09e-5)" "unprognostic (5.77e-2)" "unprognostic (2.48e-1)" "unprognostic (6.55e-2)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" "unprognostic (9.54e-2)" "unprognostic (2.56e-3)" "prognostic unfavorable (3.72e-4)" "unprognostic (2.92e-2)" "unprognostic (6.24e-2)" "unprognostic (1.73e-2)" 2.8 36.5 18.0 5.7 10.6 0.1 2.5 3.1 11.7 25.7 3.5 13.4 5.2 64.2 11.0 23.5 3.4 28.7 5.4 10.9 4.0 37.0 1.8 25.3 6.2 3.5 3.8 0.8 2.2 0.5 4.5 1.4 3.9 32.0 8.8 5.0 12.2 39.6 0.3 14.4 7.5 78.6 3.6 4.7 5.2 1.8 6.7 2.1 1.8 0.5 15.6 19.1 12.8 10.8 0.1 0.9 4.1 0.0 164.8 131.7 0.2 106.1 71.0 37.7 65.8 0.2 1.2 0.4 0.1 196.5 30.9 0.1 1.4 0.5 120.6 0.0 19.3 0.0 0.1 0.0 1.5 0.1 0.1 31.8 0.0 76.6 2.5 46.6 0.0 0.0 0.0 7.8 22.4 0.0 0.1 0.2 3.5 0.0 0.7 1.1 0.4 0.2 46.3 0.4 2.8 0.2 0.0 0.4 2.4 9.6 0.1 5.9 0.5 17.4 15.9 310.0 56.1 4.1 0.0 0.0 43.9 0.0 51.9 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.1 18.0 10.6 3.1 11.7 10.9 4.0 3.5 3.8 3.9 3.6 6.7 10.8 0.4 0.0 1.3 92.7 5.4 28.0 0.4 0.1 153.1 0.3 0.4 0.6 0.7 0.0 2.5 1.8 0.0 0.9 2.7 0.0 0.0 0.6 70.2 1.0 57.8 0.6 0.0 0.0 36.0 0.0 1.5 23.9 0.5 1.2 3.8 0.0 0.0 0.0 0.4 0.0 8.6 0.0 0.0 0.3 4.7 11.8 0.3 0.3 7.2 4.7 0.0 16.4 0.0 33.7 1.1 0.4 0.0 0.4 9.5 1.5 0.0 0.3 0.0 0.8 0.0 6.2 3.3 0.5 0.8 14.6 6.8 0.0 0.5 0.1 0.1 0.0 MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" NA NA 350000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "HPA007200: AB_1854079" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-3)" "unprognostic (7.34e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (1.79e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (6.58e-2)" 18.9 50.5 45.4 16.7 47.3 11.7 20.1 52.2 49.2 23.9 41.1 31.8 45.6 23.6 35.3 27.7 27.8 16.0 44.8 46.6 47.9 31.2 39.1 14.9 20.9 55.5 50.1 30.6 31.8 31.1 22.9 16.2 56.2 27.5 31.4 33.6 23.7 22.9 52.2 16.5 33.0 22.5 45.7 23.0 20.9 26.2 50.0 23.2 23.2 70.9 24.2 24.2 19.5 47.1 27.2 36.9 29.8 34.0 66.7 32.2 26.0 22.8 37.2 38.4 53.4 36.7 35.0 38.3 48.6 33.6 30.6 65.9 60.0 66.7 36.2 29.4 74.9 68.8 35.3 39.9 47.5 32.0 19.4 43.1 16.9 36.2 64.4 58.1 52.9 45.2 23.4 30.7 50.1 23.2 34.6 14.2 16.4 40.9 31.0 35.0 28.0 94.9 45.5 30.4 55.7 24.4 26.7 47.5 28.7 43.5 65.3 21.9 24.1 22.9 19.4 17.3 22.6 75.0 48.4 25.1 47.9 45.8 17.1 2.3 16.2 5.7 28.2 17.0 37.0 27.4 38.3 32.6 23.0 31.9 56.0 40.8 2.7 43.1 15.5 19.1 53.1 29.0 45.4 47.3 52.2 49.2 46.6 47.9 55.5 50.1 56.2 45.7 50.0 47.1 5.6 6.4 15.0 7.8 10.8 1.9 7.6 16.4 5.2 23.4 9.2 10.7 54.1 7.2 10.9 14.7 4.2 31.8 9.1 28.3 15.6 19.6 18.9 5.6 9.2 9.6 10.8 4.2 4.9 8.8 11.4 10.9 6.1 8.5 15.2 13.3 6.1 18.8 23.9 35.3 6.1 19.0 8.2 7.2 2.2 31.3 11.1 6.6 3.6 3.7 9.7 20.7 12.3 2.0 6.9 12.2 33.2 8.6 11.8 7.2 70.1 31.4 7.8 16.7 6.6 8.2 10.1 34.5 9.0 9.1 2.7 16.3 11.1 21.0 16.4 6.2 MPIG6B "C6orf25, G6b, G6b-B, NG31" ENSG00000204420 "Megakaryocyte and platelet inhibitory receptor G6b" O95866 6 31718594-31726714 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Heparin-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.8;skin 1: 8.3" "Cell type enriched" "Detected in single" 14 "granulocytes: 10.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 14 "HEL: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA054404, HPA073017" Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 330000 "Cluster 15: NK-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" "Nucleoplasm, Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA054404: , HPA073017: AB_2686566" "unprognostic (1.45e-1)" "unprognostic (1.25e-1)" "unprognostic (2.93e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" "unprognostic (6.53e-2)" "unprognostic (3.53e-2)" "unprognostic (2.71e-2)" "unprognostic (1.19e-1)" "unprognostic (1.43e-2)" "unprognostic (2.70e-1)" "unprognostic (1.71e-2)" "unprognostic (1.82e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" "unprognostic (2.55e-2)" "unprognostic (1.71e-2)" 0.5 0.0 0.0 0.1 0.0 1.1 0.4 0.1 0.2 1.0 0.1 0.3 0.1 0.4 0.0 1.6 0.5 0.2 0.8 0.1 0.1 0.1 0.3 3.5 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.2 8.3 0.4 0.0 0.0 4.8 0.3 2.3 0.1 0.0 0.5 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.8 0.0 2.2 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 MPL "CD110, THPOR, TPOR" ENSG00000117400 "MPL proto-oncogene, thrombopoietin receptor" P40238 1 43337818-43354466 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Erythroid cells: 3.0;Excitatory neurons: 2.0;Oligodendrocytes: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enriched" "Detected in some" 57 "HEL: 77.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Low region specificity" "Detected in many" HPA007619 Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Nuclear membrane" "HPA007619: AB_1854080" "unprognostic (2.74e-1)" "unprognostic (6.56e-2)" "unprognostic (2.95e-1)" "unprognostic (8.71e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.22e-2)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (5.94e-4)" "unprognostic (1.51e-1)" "unprognostic (1.19e-4)" "unprognostic (2.39e-1)" "unprognostic (3.26e-1)" "unprognostic (1.03e-4)" "unprognostic (1.42e-1)" 0.6 0.4 0.8 0.2 1.7 1.8 0.4 0.8 1.3 0.3 0.1 0.3 0.3 0.7 1.2 0.5 0.8 0.3 1.0 0.6 1.2 0.4 0.4 0.6 0.2 1.2 1.0 2.9 0.8 0.4 0.0 0.3 1.1 0.9 0.4 1.5 0.4 0.7 0.6 0.5 0.2 0.7 0.7 0.4 0.5 1.2 1.1 0.1 0.9 0.3 0.1 0.2 0.0 2.8 0.4 0.7 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.3 0.1 0.3 0.1 0.0 0.6 0.0 0.2 0.0 0.4 0.1 77.4 1.2 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.5 0.1 0.1 0.2 0.0 0.2 0.7 0.6 0.4 0.2 0.6 0.1 0.2 0.2 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.2 1.4 0.1 0.1 0.3 0.1 1.8 0.8 1.7 0.8 1.3 0.6 1.2 1.2 1.0 1.1 0.7 1.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MPO ENSG00000005381 Myeloperoxidase P05164 17 58269855-58280935 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "bone marrow: 4023.1" "Cell type enriched" "Detected in some" 30 "Erythroid cells: 87.4" "Cancer enhanced" "Detected in single" "stomach cancer: 1.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 6.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 94 "HL-60: 3517.4;NB-4: 4589.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000059, HPA021147, HPA061464" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" No NA 576000000 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles Nucleoplasm "CAB000059: AB_2335676, HPA021147: AB_1854083, HPA061464: AB_2684531" "unprognostic (1.91e-1)" "unprognostic (9.08e-2)" "unprognostic (4.62e-2)" "unprognostic (2.90e-2)" "unprognostic (2.13e-3)" "unprognostic (2.78e-1)" "unprognostic (3.23e-1)" "unprognostic (2.91e-1)" "unprognostic (2.56e-1)" "unprognostic (1.68e-1)" "unprognostic (6.92e-2)" "unprognostic (8.34e-3)" "unprognostic (4.91e-2)" "unprognostic (3.07e-3)" "unprognostic (2.83e-1)" "unprognostic (1.14e-2)" "unprognostic (8.05e-2)" 0.5 0.4 0.8 0.6 0.6 4023.1 0.3 0.6 1.1 0.0 0.3 0.2 0.0 0.2 1.1 0.1 0.1 0.3 1.1 0.8 0.7 0.2 1.8 8.4 1.7 0.9 1.0 0.1 0.1 0.0 1.5 1.4 0.9 0.2 0.2 0.4 66.3 0.1 1.1 4.3 0.2 0.3 0.8 21.7 0.1 0.4 0.8 10.9 0.3 0.3 0.2 0.5 0.1 0.7 0.4 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 3517.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4589.9 0.0 0.0 0.0 5.3 3.2 0.6 0.0 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 4.0 0.0 0.0 6.2 0.0 0.0 3.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.4 0.0 0.6 0.0 0.1 7.5 0.8 0.6 0.6 1.1 0.8 0.7 0.9 1.0 0.9 0.8 0.8 0.7 0.0 0.0 0.5 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.9 0.0 0.5 0.1 0.0 0.1 0.0 87.4 0.3 0.2 0.9 0.7 0.0 0.0 0.0 0.0 0.7 0.3 0.9 0.0 0.2 0.0 0.0 1.2 0.0 1.3 0.0 2.9 0.0 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.1 0.3 0.1 0.0 0.1 0.6 0.0 0.0 0.0 MPPED1 "239AB, C22orf1, FAM1A" ENSG00000186732 "Metallophosphoesterase domain containing 1" O15442 22 43411196-43507848 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 58.6;liver: 24.5" "Group enriched" "Detected in some" 5 "Excitatory neurons: 69.4;Inhibitory neurons: 68.6" "Cancer enhanced" "Detected in some" "liver cancer: 1.6" "Group enriched" "Detected in many" 214 "amygdala: 18.6;basal ganglia: 30.2;cerebral cortex: 58.6;hippocampal formation: 24.2;white matter: 22.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 5.3;SCLC-21H: 2.3" "Group enriched" "Detected in all" 5 "amygdala: 105.7;basal ganglia: 66.2;cerebral cortex: 163.5;hippocampal formation: 174.4;white matter: 106.3" "Group enriched" "Detected in all" 6 "cerebral cortex: 95.0;hippocampal formation: 83.0" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.15e-1)" "unprognostic (4.29e-1)" "unprognostic (8.17e-2)" "unprognostic (4.81e-2)" "unprognostic (9.62e-2)" "unprognostic (1.03e-1)" "unprognostic (7.47e-2)" "unprognostic (2.04e-1)" "unprognostic (3.19e-1)" "unprognostic (4.46e-4)" "unprognostic (1.09e-1)" "unprognostic (4.32e-3)" "unprognostic (1.30e-1)" "unprognostic (2.87e-1)" "unprognostic (6.92e-3)" 0.0 0.1 18.6 0.0 30.2 0.0 0.1 0.0 58.6 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.1 24.2 0.0 0.1 24.5 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.7 0.0 0.0 0.9 0.0 0.5 1.4 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.8 1.9 0.0 0.4 0.0 0.0 0.0 0.3 0.3 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 18.6 30.2 0.0 58.6 24.2 0.0 0.0 0.0 0.0 0.1 0.0 22.5 0.1 0.0 0.0 3.6 0.0 0.5 0.1 0.0 0.0 2.7 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 68.6 0.2 0.0 0.6 0.0 2.7 0.6 0.0 0.0 4.7 0.0 0.5 0.0 2.0 13.3 0.0 0.0 7.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MPZL1 "FLJ21047, PZR" ENSG00000197965 "Myelin protein zero like 1" O95297 1 167721192-167791919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 183.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 183.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026966, HPA063538" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA026966: AB_10600931, HPA063538: AB_2685034" "unprognostic (6.54e-2)" "unprognostic (9.26e-3)" "unprognostic (4.59e-2)" "unprognostic (4.88e-1)" "unprognostic (2.18e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (4.27e-6)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.22e-1)" "unprognostic (3.41e-2)" "unprognostic (2.59e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (3.99e-7)" "unprognostic (3.55e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (8.08e-4)" "unprognostic (4.21e-2)" 74.8 34.1 23.1 49.2 21.6 8.3 91.6 22.0 21.8 63.1 40.1 60.1 40.8 50.0 27.4 52.9 60.1 67.7 52.4 22.1 28.3 28.6 23.0 42.3 35.2 25.7 30.0 46.4 27.5 28.4 33.0 68.9 30.7 41.8 59.4 12.7 73.1 38.9 14.7 34.0 41.0 62.6 26.4 29.2 43.8 48.2 28.6 29.3 39.5 26.8 45.9 74.7 51.3 24.9 88.5 126.3 96.9 75.8 303.4 137.2 304.8 134.5 172.7 86.3 106.4 234.4 119.5 31.0 152.9 171.6 76.1 144.2 97.5 149.0 72.6 70.9 52.8 25.5 63.5 56.7 188.5 30.2 16.1 126.1 183.5 137.8 153.4 121.4 116.4 93.6 97.1 63.5 103.0 29.3 103.6 36.2 61.9 176.7 53.5 62.5 82.7 137.5 131.4 84.6 55.7 91.8 119.6 122.4 69.7 221.9 66.6 16.0 132.8 97.9 44.1 127.5 73.8 94.0 157.2 142.8 140.8 35.3 15.8 7.7 29.1 20.0 2.8 24.8 1.3 14.7 2.8 4.1 38.5 8.8 7.7 2.6 183.8 10.4 34.6 43.9 0.5 11.0 23.1 21.6 22.0 21.8 22.1 28.3 25.7 30.0 30.7 26.4 28.6 24.9 52.9 28.9 30.0 31.0 15.1 76.3 78.5 57.6 35.9 8.8 75.9 73.9 6.3 20.0 49.6 20.2 6.2 128.7 21.1 67.1 5.9 63.2 1.8 14.5 40.4 56.7 47.8 10.1 32.8 75.6 145.2 118.2 41.3 23.0 3.8 75.3 24.3 23.3 37.7 10.1 27.9 39.7 20.3 28.2 31.9 4.9 69.9 23.5 16.0 60.0 84.0 11.8 3.1 141.8 1.7 81.0 41.6 83.8 23.5 141.7 55.5 10.1 28.3 13.9 19.7 18.6 48.6 8.9 26.8 41.2 55.5 76.9 8.6 49.4 61.0 57.7 MPZL3 ENSG00000160588 "Myelin protein zero like 3" Q6UWV2 11 118226690-118252365 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.3;skin 1: 30.4" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 43.8;Suprabasal keratinocytes: 63.9;T-cells: 44.3;Urothelial cells: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 6 "basophil: 44.3;eosinophil: 99.4;MAIT T-cell: 28.9;neutrophil: 87.8" "Group enriched" "Detected in all" 8 "granulocytes: 99.4;T-cells: 28.9" "Cell line enhanced" "Detected in many" "CAPAN-2: 26.3;HMC-1: 29.0;MCF7: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029116 Approved "Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "HPA029116: AB_10610142" "unprognostic (2.54e-2)" "unprognostic (1.24e-1)" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (3.13e-3)" "unprognostic (1.52e-1)" "unprognostic (8.74e-3)" "unprognostic (2.86e-2)" "unprognostic (9.82e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (4.98e-4)" "unprognostic (4.86e-2)" "unprognostic (1.58e-2)" "unprognostic (1.89e-1)" "unprognostic (3.90e-1)" "prognostic favorable (3.64e-4)" "unprognostic (1.20e-1)" 3.3 0.5 0.7 4.7 1.0 7.3 8.2 2.8 0.7 11.5 1.7 5.6 5.4 1.5 4.9 33.3 5.4 7.6 1.6 0.7 0.8 3.1 7.5 7.9 4.8 1.0 0.7 0.5 7.2 6.7 3.8 0.8 0.9 5.6 6.1 1.3 11.7 2.7 1.7 30.4 5.3 1.5 0.7 6.0 6.8 1.1 0.8 2.8 6.1 0.9 12.6 4.4 16.8 0.7 5.0 0.6 0.0 0.7 0.0 0.0 0.7 0.6 0.1 0.1 0.1 16.7 26.3 4.9 12.5 0.0 1.9 6.8 1.2 5.6 0.1 0.3 2.0 3.0 1.4 8.1 0.2 4.1 29.0 0.3 13.6 0.0 5.4 0.0 8.8 3.3 3.8 2.7 0.1 17.1 1.9 2.2 2.4 16.5 1.2 0.0 0.0 7.4 10.0 6.2 3.4 0.3 6.6 8.6 0.5 1.3 15.4 2.2 4.3 0.1 1.3 0.1 0.1 0.4 5.1 3.1 0.1 0.1 0.3 44.3 6.0 99.4 7.0 3.7 28.9 1.7 11.3 9.6 8.1 1.9 8.4 6.9 87.8 8.2 2.6 1.1 8.4 5.3 0.7 1.0 2.8 0.7 0.7 0.8 1.0 0.7 0.9 0.7 0.8 0.7 2.4 16.0 26.9 0.0 4.9 35.6 21.7 11.8 9.6 0.3 28.2 14.7 1.7 5.7 15.9 9.2 2.1 0.6 9.6 19.6 0.0 10.5 7.4 32.7 4.1 4.9 12.0 0.4 2.2 8.8 0.7 1.6 18.3 34.0 1.3 0.1 2.2 8.2 1.3 0.0 2.3 5.1 14.2 5.1 18.7 7.7 0.0 5.5 10.6 1.9 3.8 0.3 4.1 0.5 0.3 16.7 9.1 0.4 6.6 30.6 9.3 1.1 43.8 1.7 0.0 0.4 2.3 1.7 0.8 14.3 63.9 1.6 44.3 0.2 8.1 46.4 MR1 HLALS ENSG00000153029 "Major histocompatibility complex, class I-related" Q95460 1 181033425-181061938 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048304 Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA048304: AB_2680347" "unprognostic (6.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.31e-2)" "unprognostic (1.96e-1)" "unprognostic (8.66e-3)" "unprognostic (4.37e-2)" "unprognostic (1.96e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.18e-1)" "unprognostic (3.49e-2)" "unprognostic (6.41e-2)" "unprognostic (1.05e-2)" "unprognostic (7.40e-3)" "unprognostic (4.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.07e-2)" 8.6 9.6 3.2 14.2 3.3 11.1 9.7 2.2 3.5 10.2 5.8 6.7 7.4 9.5 9.6 9.6 10.4 12.7 6.2 3.1 3.8 9.9 10.6 18.0 14.6 4.7 3.3 13.6 3.7 14.0 8.9 13.5 3.7 10.9 8.1 1.5 5.9 10.5 2.1 8.7 6.9 12.5 3.8 12.3 8.7 2.6 4.4 20.2 16.7 3.8 15.2 16.3 7.4 4.8 7.9 5.4 0.1 4.6 32.2 38.8 13.9 15.5 42.2 12.7 21.5 2.2 31.9 9.7 31.6 28.1 9.9 20.5 0.7 18.3 11.1 29.6 5.2 14.2 5.6 9.8 10.8 11.5 40.6 25.2 49.6 18.9 20.3 23.7 1.3 17.8 26.7 25.6 24.9 8.8 12.1 8.3 0.1 0.1 0.8 13.7 0.3 27.3 13.9 23.1 0.2 0.3 8.2 14.8 10.9 6.0 15.4 24.6 8.1 12.5 1.7 21.8 7.7 42.2 15.3 17.9 11.7 14.7 1.2 32.6 21.8 22.9 16.3 27.4 14.6 14.3 14.6 14.6 18.8 18.3 10.8 16.2 14.7 19.0 23.6 10.2 17.0 15.2 3.2 3.3 2.2 3.5 3.1 3.8 4.7 3.3 3.7 3.8 4.4 4.8 4.4 19.2 32.4 8.8 14.7 5.0 8.3 32.6 12.0 0.8 7.7 6.1 4.1 8.6 20.9 14.7 0.0 17.5 15.9 1.6 5.9 10.8 0.3 5.9 12.1 4.9 2.4 11.4 3.1 6.4 9.5 12.8 2.6 7.3 17.1 13.5 3.6 8.9 25.8 0.0 1.7 2.7 32.6 25.2 9.1 0.4 10.8 25.3 7.2 11.2 30.8 4.1 26.8 0.0 0.5 7.5 4.5 12.0 9.1 7.4 2.2 2.4 15.3 0.6 0.0 8.6 9.2 0.4 1.6 10.9 5.4 24.5 15.7 22.4 3.5 13.4 MRPL2 "CGI-22, MRP-L14, RPML14" ENSG00000112651 "Mitochondrial ribosomal protein L2" Q5T653 6 43054029-43059438 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007455, HPA064814" Approved Supported Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA007455: AB_1079410, HPA064814: AB_2685358" "unprognostic (2.31e-1)" "unprognostic (1.49e-2)" "unprognostic (3.06e-1)" "unprognostic (1.48e-2)" "unprognostic (3.34e-1)" "unprognostic (1.62e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (3.17e-1)" "prognostic favorable (6.01e-4)" "unprognostic (3.07e-1)" "unprognostic (1.79e-1)" "unprognostic (3.24e-2)" "unprognostic (6.42e-2)" "unprognostic (2.33e-2)" "unprognostic (3.13e-1)" "unprognostic (2.78e-1)" 26.5 32.4 27.9 12.6 28.8 20.0 26.0 31.0 37.6 23.2 27.9 27.5 25.6 23.5 13.7 24.6 22.2 10.1 48.2 28.3 31.7 33.7 51.2 18.6 13.4 29.8 28.9 24.5 27.1 29.6 29.5 13.3 30.1 22.0 16.8 10.9 22.6 17.6 75.1 25.1 20.3 12.0 27.4 19.9 23.6 19.7 29.0 17.7 26.7 56.7 14.4 22.6 21.4 28.9 47.9 43.1 20.3 39.3 28.4 20.7 38.9 20.4 24.8 47.3 41.3 109.0 15.4 61.8 42.3 24.6 36.2 49.9 50.5 48.7 27.8 30.4 90.9 46.8 34.9 109.5 57.2 43.5 21.0 27.6 51.4 52.5 82.8 22.6 32.6 68.7 84.6 36.6 23.6 84.0 48.1 127.1 22.7 175.7 49.5 59.0 25.1 77.3 38.2 26.3 51.3 27.4 18.2 39.4 73.4 18.6 41.4 73.9 27.3 27.6 40.0 35.7 58.7 47.7 44.9 115.2 21.5 65.2 27.8 17.5 37.8 30.2 28.4 40.9 36.5 46.5 31.8 33.6 54.3 48.6 32.7 32.3 9.8 38.5 33.7 56.1 39.2 31.3 27.9 28.8 31.0 37.6 28.3 31.7 29.8 28.9 30.1 27.4 29.0 28.9 36.8 22.4 18.6 5.5 27.5 24.3 32.0 86.5 19.4 22.7 25.9 30.0 37.5 38.6 48.9 60.7 27.1 74.0 21.3 43.1 185.9 59.1 94.0 30.6 34.1 32.1 30.6 35.3 5.3 53.7 53.1 31.1 30.1 32.5 28.5 43.1 33.2 75.9 49.3 5.0 5.8 44.2 69.2 23.7 26.6 37.0 55.0 22.9 53.4 2.8 41.3 44.7 43.3 2.0 5.5 44.2 51.3 51.6 35.6 31.6 77.6 159.4 40.4 23.4 26.3 32.5 82.7 53.1 41.7 35.7 27.1 63.5 27.2 59.0 65.7 28.7 MRPL21 ENSG00000197345 "Mitochondrial ribosomal protein L21" Q7Z2W9 11 68891276-68903835 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051657 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA051657: AB_2681565" "unprognostic (1.80e-1)" "unprognostic (6.09e-2)" "unprognostic (4.80e-2)" "unprognostic (8.96e-3)" "unprognostic (9.25e-3)" "prognostic unfavorable (5.97e-4)" "unprognostic (3.23e-2)" "unprognostic (1.51e-1)" "unprognostic (1.09e-1)" "unprognostic (1.06e-1)" "unprognostic (4.84e-2)" "unprognostic (7.36e-2)" "unprognostic (1.26e-2)" "unprognostic (3.73e-2)" "unprognostic (1.72e-1)" "unprognostic (4.36e-2)" "unprognostic (3.12e-1)" 43.5 44.4 56.0 34.0 57.3 60.5 52.5 62.8 71.9 45.3 57.7 67.1 38.7 50.4 48.4 58.4 45.2 27.1 120.2 57.6 59.5 68.0 66.1 31.5 43.8 59.5 57.4 48.6 53.6 56.3 44.7 33.1 59.6 44.1 42.5 29.7 99.5 39.1 131.0 50.4 46.0 35.1 56.9 37.0 53.0 47.0 57.9 37.2 44.7 109.1 42.9 49.8 44.9 56.9 105.2 145.6 86.0 82.3 59.1 63.5 101.4 71.8 77.2 132.8 90.4 297.3 132.7 163.5 157.2 78.0 122.0 129.9 143.8 138.6 102.8 109.7 112.6 114.4 102.4 181.0 116.6 201.4 83.4 95.0 69.4 134.1 156.0 64.7 93.7 115.1 229.2 119.4 80.7 196.7 95.5 210.5 78.0 307.6 210.3 135.2 102.9 253.0 134.0 120.8 139.3 111.3 91.1 181.6 302.7 68.7 188.7 115.4 79.3 90.6 90.6 201.3 135.5 88.9 149.5 232.3 120.6 120.4 125.7 79.6 113.0 61.6 72.4 122.8 77.1 162.2 94.5 78.8 124.2 105.8 89.3 74.1 32.1 93.3 114.2 92.0 113.2 114.0 56.0 57.3 62.8 71.9 57.6 59.5 59.5 57.4 59.6 56.9 57.9 56.9 38.9 35.3 38.7 5.5 47.4 50.2 76.8 145.1 68.9 36.3 56.5 65.4 179.8 67.2 82.0 80.9 8.4 122.8 34.6 127.7 299.3 106.7 176.9 72.2 59.8 50.4 61.7 56.0 5.6 105.3 114.8 53.9 42.8 63.0 65.2 31.8 40.7 115.9 110.4 11.8 6.4 115.6 85.5 56.3 41.3 227.3 74.9 47.0 78.2 1.0 69.8 69.0 34.0 2.0 5.1 86.3 93.0 72.2 63.8 79.6 150.6 272.9 72.8 51.4 26.3 59.3 85.8 86.6 60.5 83.2 51.9 81.3 44.2 55.0 141.6 75.0 MRPL22 "HSPC158, MRP-L25, RPML25" ENSG00000082515 "Mitochondrial ribosomal protein L22" Q9NWU5 5 154941073-154969411 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047063 Uncertain Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047063: AB_2679919" "unprognostic (9.17e-2)" "unprognostic (1.18e-2)" "unprognostic (2.16e-2)" "unprognostic (2.56e-2)" "unprognostic (5.42e-2)" "unprognostic (6.65e-2)" "unprognostic (1.80e-2)" "unprognostic (4.86e-2)" "unprognostic (2.03e-1)" "unprognostic (3.01e-3)" "unprognostic (3.40e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (3.54e-1)" "unprognostic (2.69e-1)" "unprognostic (4.09e-2)" "unprognostic (4.29e-2)" 23.9 38.4 18.4 20.3 18.4 40.9 26.3 20.0 27.9 20.7 17.7 28.4 26.1 20.5 26.0 30.8 18.9 15.4 46.3 18.5 19.0 37.5 49.3 19.6 28.5 19.5 18.8 18.1 30.3 31.2 23.8 24.2 19.7 19.4 28.0 17.0 24.8 19.3 38.5 23.6 22.9 20.0 18.7 26.2 27.1 29.4 18.8 28.2 23.3 34.5 27.1 24.6 21.6 19.6 68.5 65.8 57.1 79.7 43.7 55.0 67.9 47.6 55.9 93.9 118.3 191.5 82.8 93.7 82.9 40.1 100.0 61.2 83.2 90.0 99.8 32.2 94.3 36.1 64.1 110.1 57.1 81.5 47.2 36.5 59.4 63.4 76.9 41.8 161.8 84.6 55.2 81.9 58.8 100.8 74.1 78.3 43.5 74.0 50.6 67.4 49.6 97.9 93.1 50.9 65.4 24.3 62.5 89.1 104.9 41.0 130.2 71.3 47.5 57.7 57.5 51.1 89.3 43.4 57.5 104.4 57.9 99.7 55.4 35.9 49.0 44.1 47.5 59.7 48.7 72.3 51.5 51.3 66.6 61.5 47.7 54.6 19.8 64.0 60.4 51.9 75.1 62.4 18.4 18.4 20.0 27.9 18.5 19.0 19.5 18.8 19.7 18.7 18.8 19.6 55.2 25.6 28.1 11.1 52.2 63.9 54.4 191.6 43.9 28.1 45.9 67.9 213.2 64.3 95.6 60.7 27.1 144.6 37.9 46.6 223.0 114.9 56.2 49.6 44.4 69.2 49.6 64.0 13.0 127.1 132.6 64.7 27.0 41.3 45.0 56.2 51.4 85.2 99.3 32.0 11.8 65.6 79.3 33.2 57.1 29.3 66.2 35.7 51.6 2.8 61.3 35.9 56.7 11.1 20.1 113.9 83.4 75.2 71.1 47.2 68.1 203.7 89.0 27.1 32.9 48.5 86.7 167.7 67.0 50.3 65.8 78.5 48.4 122.2 78.5 54.6 MRPL24 MRP-L18 ENSG00000143314 "Mitochondrial ribosomal protein L24" Q96A35 1 156737303-156741590 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 213.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030295, HPA054323" Approved "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA030295: AB_10600932, HPA054323: AB_2732583" "unprognostic (1.51e-1)" "unprognostic (1.52e-1)" "unprognostic (2.26e-2)" "unprognostic (1.47e-2)" "unprognostic (2.83e-1)" "unprognostic (3.69e-2)" "unprognostic (1.71e-2)" "unprognostic (3.11e-1)" "unprognostic (1.63e-1)" "unprognostic (5.80e-2)" "unprognostic (3.05e-3)" "unprognostic (2.73e-2)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.47e-1)" "unprognostic (8.75e-2)" "unprognostic (3.74e-1)" "unprognostic (1.94e-1)" 78.1 93.8 75.4 43.0 78.6 24.0 69.8 79.6 81.2 51.3 71.4 70.3 40.7 58.3 94.6 55.4 72.7 33.8 108.4 74.0 77.4 77.9 130.6 37.2 46.1 77.7 75.9 65.6 100.2 86.1 41.1 41.5 78.9 49.1 67.8 26.9 71.2 65.7 149.6 50.7 41.8 76.6 76.3 43.1 62.0 37.4 77.3 42.8 52.5 143.0 57.1 67.1 48.0 82.0 146.0 238.2 50.2 62.0 157.0 167.6 98.7 115.6 72.2 153.6 86.5 96.5 149.7 112.1 189.3 153.2 74.9 141.3 121.8 238.9 153.3 136.6 152.7 104.9 164.9 94.7 176.8 115.9 70.8 156.5 205.0 232.3 243.4 92.9 136.4 136.5 105.4 129.2 155.1 259.9 130.6 115.2 93.0 495.3 289.8 83.7 134.7 229.1 192.3 105.2 64.0 129.4 70.3 391.6 192.5 95.4 233.9 130.6 104.1 141.8 108.9 141.1 200.3 144.1 131.5 116.1 133.8 135.5 143.8 38.3 62.3 11.2 63.1 77.4 95.8 87.2 82.3 77.5 81.5 86.9 81.4 86.0 3.3 97.1 75.0 68.4 72.0 93.5 75.4 78.6 79.6 81.2 74.0 77.4 77.7 75.9 78.9 76.3 77.3 82.0 26.3 32.1 31.6 3.9 33.7 30.5 67.0 65.4 39.3 13.8 46.8 51.3 157.0 80.1 49.1 42.3 4.2 92.4 27.5 28.0 154.6 53.5 26.7 31.5 45.0 40.9 36.0 22.9 5.7 76.6 87.9 51.0 36.7 37.0 60.3 30.9 35.7 133.6 79.7 15.2 6.3 45.7 36.7 27.3 29.4 13.4 55.9 29.1 74.7 1.9 47.9 22.2 36.0 4.5 10.0 40.2 35.3 53.0 43.4 53.7 44.9 213.2 41.7 13.7 32.9 53.0 62.0 46.8 48.5 66.1 36.7 40.8 28.7 59.7 69.5 62.1 MRPL27 ENSG00000108826 "Mitochondrial ribosomal protein L27" Q9P0M9 17 50367857-50373207 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 377.6;Proximal tubular cells: 409.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021416 Approved "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA021416: AB_1854103" "unprognostic (2.09e-1)" "unprognostic (2.27e-2)" "unprognostic (4.66e-2)" "unprognostic (8.23e-2)" "unprognostic (2.10e-2)" "unprognostic (2.99e-2)" "unprognostic (7.03e-2)" "unprognostic (1.42e-1)" "unprognostic (8.79e-2)" "unprognostic (1.96e-2)" "unprognostic (2.43e-2)" "unprognostic (4.27e-2)" "unprognostic (1.65e-1)" "unprognostic (1.14e-1)" "unprognostic (7.61e-2)" "unprognostic (3.14e-2)" "unprognostic (7.76e-3)" 51.4 92.4 103.3 36.8 105.9 35.7 55.2 108.9 129.4 48.5 105.6 73.5 53.8 46.2 115.5 72.8 44.1 29.9 106.5 102.6 106.3 90.7 109.4 37.3 44.8 106.6 105.7 45.9 59.2 75.5 52.3 57.2 107.4 58.2 84.4 32.9 50.3 45.0 141.1 60.2 52.2 50.9 106.1 45.6 91.2 42.4 109.0 61.2 49.7 140.5 64.7 58.0 51.0 108.0 160.2 231.3 105.5 69.8 66.5 98.9 154.3 117.1 111.8 216.9 195.5 535.5 82.6 139.3 143.5 146.0 168.0 97.3 160.9 177.8 176.2 142.2 273.0 145.5 199.8 393.1 123.4 121.9 125.3 114.3 242.9 172.8 103.0 94.7 149.0 75.8 157.4 81.0 153.4 304.2 135.6 154.0 76.4 279.4 252.4 74.4 143.6 114.5 187.8 213.6 108.1 130.4 55.0 71.3 104.9 140.0 171.2 100.6 89.8 145.0 110.5 109.4 192.1 97.6 120.5 127.8 97.6 101.7 76.4 212.7 175.6 124.6 99.3 209.2 82.9 211.4 117.2 104.5 177.1 186.4 113.9 99.0 27.9 108.7 153.6 193.5 159.0 179.3 103.3 105.9 108.9 129.4 102.6 106.3 106.6 105.7 107.4 106.1 109.0 108.0 33.6 38.5 43.7 12.7 50.7 60.0 97.2 220.9 56.9 35.5 50.1 65.8 180.5 88.6 111.2 90.1 14.6 240.7 36.8 179.7 377.6 136.5 27.7 60.1 61.7 58.1 103.0 55.3 10.0 146.5 181.9 70.6 99.9 63.9 29.7 52.1 57.8 221.4 150.6 15.2 12.9 193.3 132.2 52.5 33.9 31.1 83.0 52.0 69.4 12.2 88.8 72.5 42.2 15.6 14.5 153.8 139.0 83.8 58.2 83.9 199.5 409.5 73.5 42.1 72.3 57.1 85.8 88.7 74.6 81.6 75.4 273.4 36.4 97.5 155.3 102.6 MRPL32 "bMRP-59b, HSPC283, L32mt, MRP-L32" ENSG00000106591 "Mitochondrial ribosomal protein L32" Q9BYC8 7 42932376-42948958 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048965 Uncertain "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 1: Thyroid gland - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA048965: AB_2680576" "unprognostic (1.15e-1)" "unprognostic (2.31e-1)" "unprognostic (3.82e-2)" "unprognostic (1.40e-1)" "unprognostic (5.90e-3)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-2)" "unprognostic (8.22e-3)" "unprognostic (8.60e-2)" "unprognostic (1.80e-1)" "unprognostic (5.05e-3)" "unprognostic (4.09e-2)" "unprognostic (1.43e-2)" "unprognostic (2.97e-1)" "unprognostic (2.21e-2)" 44.7 71.4 35.8 32.3 37.1 28.4 41.8 36.5 42.8 29.4 46.1 47.4 46.7 33.4 57.2 38.7 38.5 42.1 74.1 36.8 39.7 82.5 120.3 28.7 39.2 36.9 36.7 45.4 52.1 53.0 26.3 34.6 36.8 57.3 45.7 15.9 46.2 34.7 53.6 26.9 39.5 34.4 36.4 29.8 43.7 25.5 36.8 36.9 42.2 66.3 43.3 55.2 27.5 37.8 67.9 94.3 63.3 99.7 97.0 79.9 72.8 101.9 74.2 84.3 95.9 116.3 71.7 145.3 95.8 59.4 141.3 150.3 98.6 112.0 99.1 94.2 116.6 70.7 75.4 128.5 142.2 121.4 66.8 91.8 84.0 62.6 109.2 72.7 106.0 97.6 132.5 73.4 108.1 104.4 83.2 207.1 160.9 160.2 139.3 81.3 73.6 150.4 188.2 138.7 77.4 69.1 82.4 224.2 89.0 92.2 126.3 90.4 93.4 72.5 117.3 77.3 143.6 120.9 215.1 160.4 55.0 156.6 157.9 181.9 89.7 147.1 77.8 101.6 104.3 154.6 114.1 102.3 95.9 122.9 120.3 113.9 18.3 102.9 91.0 94.3 160.6 117.9 35.8 37.1 36.5 42.8 36.8 39.7 36.9 36.7 36.8 36.4 36.8 37.8 53.3 54.5 39.8 6.2 47.8 131.5 88.5 191.2 55.2 20.5 68.7 87.4 93.3 70.1 92.7 58.8 8.4 110.9 47.6 46.1 180.0 111.5 8.3 50.8 70.5 68.7 46.8 44.4 16.5 101.0 98.4 61.5 38.7 57.4 64.0 43.5 57.8 104.1 61.8 16.8 14.1 64.2 101.7 40.6 50.2 8.4 52.8 34.1 64.0 5.6 57.7 16.3 35.0 11.6 17.1 97.6 55.4 50.8 43.8 103.1 77.4 211.7 70.1 23.2 52.6 73.1 113.5 34.3 72.5 65.2 109.4 89.6 45.4 117.4 104.6 105.1 MRPL34 "L34mt, MGC24974, MGC2633" ENSG00000130312 "Mitochondrial ribosomal protein L34" Q9BQ48 19 17292609-17306843 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 403.0;Proximal tubular cells: 414.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049276 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA049276: AB_2680697" "unprognostic (1.21e-2)" "unprognostic (3.22e-2)" "unprognostic (4.85e-2)" "unprognostic (1.07e-1)" "unprognostic (2.61e-2)" "unprognostic (4.27e-2)" "unprognostic (1.46e-1)" "unprognostic (4.93e-2)" "unprognostic (1.29e-1)" "unprognostic (5.45e-2)" "prognostic favorable (4.87e-4)" "unprognostic (2.09e-1)" "prognostic favorable (4.29e-6)" "unprognostic (2.44e-1)" "unprognostic (2.42e-1)" "unprognostic (1.23e-1)" "unprognostic (2.18e-2)" 69.6 115.4 64.0 27.5 67.0 26.2 64.7 69.2 72.2 51.4 96.7 99.7 71.5 58.7 23.5 62.8 45.6 17.6 178.2 63.4 69.5 126.0 195.0 47.1 28.6 64.3 64.1 40.9 69.5 91.8 74.1 20.3 64.6 55.3 29.8 31.6 65.3 40.2 210.5 60.6 75.8 18.3 64.1 55.8 87.7 93.6 70.7 38.0 61.5 139.6 21.8 64.0 50.6 66.0 91.9 55.3 35.4 45.4 88.2 48.7 132.1 45.4 47.7 36.6 44.8 53.6 64.2 115.2 126.7 25.2 50.7 73.6 57.1 53.5 25.9 171.3 198.5 81.4 87.2 119.2 78.7 89.2 103.9 56.6 71.2 38.0 52.1 38.9 57.8 95.5 119.6 136.4 35.7 86.7 113.4 187.4 97.6 147.2 293.8 97.9 52.0 160.9 107.9 68.6 84.1 136.7 42.6 67.2 105.9 37.0 58.7 74.3 49.0 52.7 32.8 151.6 87.4 186.5 305.3 129.0 65.4 161.7 49.1 169.6 162.3 159.5 172.4 177.0 192.5 204.0 203.5 177.3 178.1 211.0 197.5 172.2 52.3 141.7 107.0 233.6 210.8 276.7 64.0 67.0 69.2 72.2 63.4 69.5 64.3 64.1 64.6 64.1 70.7 66.0 64.4 35.3 41.4 13.7 51.7 60.7 33.0 128.5 74.0 50.2 81.7 108.2 153.4 91.5 64.6 82.8 20.9 118.5 94.1 138.9 403.0 88.5 57.6 48.1 46.7 54.2 68.3 45.5 16.1 68.8 112.1 55.6 60.1 45.4 39.3 37.1 59.6 290.3 172.4 42.1 16.7 125.4 134.3 70.1 55.9 31.9 82.0 61.4 81.8 6.5 90.0 45.0 97.9 6.0 12.8 64.7 99.1 91.7 80.3 45.7 219.5 414.8 42.3 49.7 72.3 48.1 69.7 233.1 14.9 93.2 72.0 78.3 62.0 109.5 130.6 36.7 MRPL35 ENSG00000132313 "Mitochondrial ribosomal protein L35" Q9NZE8 2 86199355-86213790 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043482 Uncertain "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA043482: AB_10959449" "unprognostic (3.68e-2)" "unprognostic (6.24e-2)" "unprognostic (9.14e-3)" "unprognostic (1.68e-2)" "unprognostic (9.38e-3)" "unprognostic (7.72e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (9.81e-2)" "unprognostic (1.76e-2)" "unprognostic (1.42e-2)" "unprognostic (1.62e-1)" "unprognostic (1.66e-1)" "prognostic favorable (9.96e-6)" "unprognostic (1.94e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (2.52e-3)" 25.0 29.7 19.6 24.7 22.0 20.5 25.3 21.2 26.1 18.9 18.8 55.5 57.9 17.8 13.6 31.2 21.9 19.9 83.8 20.1 21.9 47.5 46.1 15.5 35.6 19.7 19.6 17.3 19.7 45.9 12.0 20.9 20.9 19.1 58.7 23.2 24.3 25.1 69.4 14.3 43.3 30.1 20.5 21.6 32.2 16.2 21.7 29.1 19.9 113.5 40.0 32.2 18.0 21.2 83.4 35.8 53.6 55.0 55.1 51.6 77.2 71.5 51.5 88.0 64.9 31.4 69.1 154.1 79.0 61.6 70.9 71.2 109.3 64.2 98.1 89.0 51.0 88.5 25.9 80.5 44.7 143.0 68.0 38.6 75.0 95.4 46.4 42.3 81.4 82.6 111.4 66.1 82.0 50.2 82.0 97.3 56.2 107.0 46.4 71.4 143.1 129.8 90.6 60.2 45.2 43.7 66.1 106.8 116.8 37.5 43.7 57.0 62.2 70.4 85.9 89.8 112.6 49.9 157.4 170.0 61.7 150.1 65.6 30.4 36.0 19.0 21.4 48.4 24.0 45.2 31.9 28.0 41.9 41.4 37.4 29.7 5.1 23.5 50.8 42.2 40.4 32.4 19.6 22.0 21.2 26.1 20.1 21.9 19.7 19.6 20.9 20.5 21.7 21.2 17.3 22.4 15.0 7.2 17.5 7.1 20.3 67.4 11.4 21.9 17.0 20.1 135.9 18.6 42.2 18.4 31.3 49.2 15.0 46.7 97.8 42.0 3.7 22.0 28.3 19.2 26.5 35.1 11.6 43.0 49.7 19.8 23.4 22.1 21.0 21.9 15.7 52.9 65.3 23.5 12.7 31.4 48.8 23.8 6.1 5.0 12.8 23.7 10.6 12.2 32.1 21.5 19.6 5.0 11.5 41.8 29.5 17.7 29.5 17.3 52.6 82.8 24.9 25.4 26.3 17.2 47.2 14.6 26.3 29.0 8.5 27.0 14.6 38.1 56.3 25.2 MRPL36 "BRIP1, L36mt, MRP-L36, PRPL36, RPMJ" ENSG00000171421 "Mitochondrial ribosomal protein L36" Q9P0J6 5 1798385-1801366 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 472.3;Late spermatids: 471.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047238 Approved Supported "Nuclear bodies,Mitochondria" No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear bodies, Mitochondria" "HPA047238: AB_10965331" "unprognostic (2.23e-2)" "unprognostic (1.04e-1)" "unprognostic (3.57e-2)" "unprognostic (7.83e-3)" "unprognostic (2.03e-2)" "unprognostic (2.01e-2)" "unprognostic (1.09e-3)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (1.37e-2)" "unprognostic (5.39e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (8.53e-2)" "unprognostic (9.83e-2)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" 46.2 60.4 35.6 24.7 36.9 19.2 42.1 40.9 44.2 31.5 36.3 49.6 27.9 38.6 26.3 51.1 32.3 22.0 77.3 36.6 38.4 70.4 76.1 28.6 30.1 37.8 36.9 35.1 44.4 34.6 29.1 21.8 38.4 44.0 20.0 22.6 36.5 21.6 140.2 39.3 33.7 26.9 38.3 34.3 44.9 97.4 38.3 29.1 27.4 86.1 25.9 38.8 34.2 38.3 93.3 134.9 61.7 116.9 111.3 91.2 80.9 79.4 69.4 92.7 88.2 98.4 73.4 124.2 140.2 85.7 136.1 99.1 139.9 130.9 66.8 136.1 155.8 60.2 285.1 158.4 142.0 78.9 45.5 80.9 98.9 103.6 133.4 80.8 91.1 72.3 93.4 77.9 133.6 169.4 93.2 177.5 60.1 102.2 164.0 73.8 46.0 149.6 84.6 74.9 68.5 46.8 172.6 133.1 89.8 56.3 78.2 84.5 55.5 79.9 87.1 54.7 89.4 74.0 100.3 167.4 100.4 144.5 111.3 88.4 103.2 68.6 90.6 104.8 109.6 132.6 101.5 111.1 127.3 103.3 89.1 106.3 29.7 101.7 92.9 476.0 143.0 142.0 35.6 36.9 40.9 44.2 36.6 38.4 37.8 36.9 38.4 38.3 38.3 38.3 52.6 32.1 29.0 6.8 37.6 106.0 108.8 150.2 89.4 23.0 61.5 93.2 163.1 50.1 83.6 58.8 6.2 93.4 66.0 47.3 307.2 84.1 472.3 45.4 63.9 63.7 26.4 50.9 7.9 75.0 74.0 62.7 35.2 33.1 27.9 46.2 35.7 118.2 88.2 15.2 7.9 53.8 107.8 43.0 52.4 471.3 74.9 32.0 60.5 2.8 62.5 76.0 70.0 7.1 9.6 92.1 58.7 59.8 45.6 148.8 79.2 199.6 63.2 31.2 65.7 51.1 68.6 188.6 76.2 92.4 124.9 87.4 37.3 79.8 65.7 112.6 MRPL4 CGI-28 ENSG00000105364 "Mitochondrial ribosomal protein L4" Q9BYD3 19 10251901-10260055 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 1034.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051261 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA051261: AB_2681413" "unprognostic (3.33e-1)" "unprognostic (2.49e-2)" "unprognostic (8.92e-2)" "unprognostic (1.22e-2)" "unprognostic (1.90e-2)" "unprognostic (1.63e-1)" "unprognostic (2.48e-2)" "unprognostic (2.18e-1)" "unprognostic (1.59e-1)" "unprognostic (2.39e-2)" "unprognostic (4.06e-2)" "unprognostic (1.01e-3)" "unprognostic (1.15e-3)" "unprognostic (7.60e-3)" "unprognostic (2.87e-1)" "unprognostic (3.03e-1)" "unprognostic (1.11e-1)" 42.5 65.9 35.6 27.6 36.4 37.5 40.2 37.2 51.2 36.3 33.4 49.3 33.1 41.0 8.7 73.2 37.3 12.2 83.6 35.4 35.4 54.6 90.9 31.0 30.8 39.4 35.1 49.9 31.8 25.9 35.7 21.8 39.3 38.9 13.4 8.7 38.3 21.1 79.1 62.0 40.5 14.9 33.1 46.5 45.1 31.4 37.2 19.5 40.4 49.3 19.4 45.4 42.8 37.2 146.6 81.9 34.4 95.2 26.9 35.6 76.0 66.3 41.4 86.7 70.6 138.1 55.2 215.6 148.5 36.5 51.3 128.0 71.6 93.2 26.6 80.4 302.6 181.0 62.6 136.4 80.9 136.1 96.7 46.5 63.1 58.7 54.2 27.2 53.4 97.8 155.7 100.8 33.7 213.0 189.6 1034.0 98.3 91.4 300.4 140.3 51.1 219.8 53.2 89.1 85.6 75.4 56.6 124.2 104.6 16.5 67.3 90.4 71.2 83.7 75.3 182.3 134.8 148.5 189.7 218.2 72.7 189.2 74.0 6.4 53.7 17.5 35.1 74.0 38.2 36.9 34.4 39.5 83.2 41.1 31.1 31.4 4.9 47.4 60.1 71.7 43.2 36.8 35.6 36.4 37.2 51.2 35.4 35.4 39.4 35.1 39.3 33.1 37.2 37.2 46.9 16.0 27.4 11.4 53.0 86.2 60.4 115.9 76.8 50.4 58.5 85.0 12.9 44.3 49.8 40.5 8.4 187.6 43.0 57.8 144.8 74.0 25.4 44.0 52.2 39.7 44.9 37.0 17.5 77.7 76.6 46.8 63.7 45.3 26.0 81.6 25.7 80.5 95.0 32.0 17.6 70.1 52.9 36.1 38.7 10.8 51.0 42.4 46.2 8.4 58.0 45.0 45.3 10.6 12.3 84.8 39.7 50.4 79.4 79.7 59.6 133.5 27.6 35.8 13.1 39.8 61.4 38.7 42.2 120.4 98.7 149.4 42.5 141.3 104.9 78.0 MRPL46 "C15orf4, LIECG2, P2ECSL" ENSG00000259494 "Mitochondrial ribosomal protein L46" Q9H2W6 15 88459477-88467390 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Proximal tubular cells: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050166, HPA076046" Approved Supported "Nucleoplasm,Cell Junctions,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cell Junctions" "HPA050166: AB_2681039, HPA076046: " "unprognostic (1.42e-1)" "unprognostic (6.94e-3)" "unprognostic (1.02e-1)" "unprognostic (1.21e-2)" "unprognostic (3.28e-2)" "unprognostic (5.16e-2)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.79e-1)" "unprognostic (4.64e-3)" "unprognostic (7.78e-2)" "unprognostic (5.65e-2)" "prognostic favorable (2.09e-6)" "unprognostic (7.73e-2)" "unprognostic (9.18e-2)" "unprognostic (6.96e-3)" "unprognostic (1.63e-1)" 25.1 51.5 20.3 12.9 21.7 11.3 22.7 23.7 25.4 14.6 22.0 24.2 20.0 17.1 18.2 26.4 17.1 13.0 76.1 20.8 23.6 34.7 70.9 12.7 20.9 23.1 22.1 17.2 16.2 24.6 16.2 19.6 23.6 14.9 23.6 16.8 17.1 15.2 73.3 17.9 19.7 18.4 21.7 19.1 24.8 28.1 22.7 18.9 17.2 84.6 20.3 20.7 16.2 22.6 27.8 87.2 27.2 29.8 38.0 28.6 51.5 38.6 35.5 56.9 50.4 108.6 59.3 64.9 38.6 34.9 51.0 65.9 107.4 47.4 44.8 26.3 86.4 53.6 61.5 114.3 24.6 54.2 40.4 32.7 56.6 42.8 28.7 29.0 50.2 63.2 60.7 26.6 42.7 59.6 44.2 68.4 43.5 50.5 52.9 51.9 37.9 49.2 44.5 88.2 42.1 26.5 36.6 57.7 81.8 44.6 64.8 65.7 31.3 44.0 41.9 23.3 56.4 24.2 55.7 53.0 48.5 58.1 34.2 27.1 45.5 33.7 60.0 60.5 69.6 78.8 63.3 58.7 58.7 69.5 69.5 61.6 7.9 62.9 45.0 50.5 68.0 61.5 20.3 21.7 23.7 25.4 20.8 23.6 23.1 22.1 23.6 21.7 22.7 22.6 18.9 0.0 10.3 5.2 21.0 13.8 22.4 59.8 9.6 21.2 17.3 21.3 70.4 37.1 32.3 36.8 27.1 94.3 10.7 20.4 119.3 35.0 67.1 20.0 16.6 18.4 28.3 17.7 4.2 38.0 42.1 19.2 19.9 19.5 22.2 25.8 17.2 105.0 35.6 15.2 5.9 20.6 44.7 13.4 5.5 16.3 14.3 10.8 7.2 3.7 42.1 25.1 20.6 4.5 6.1 31.7 18.4 18.8 17.3 21.9 32.1 133.6 26.2 28.4 26.3 19.5 25.5 55.3 27.4 27.1 23.3 80.7 18.5 66.9 36.1 29.4 MRPL55 ENSG00000162910 "Mitochondrial ribosomal protein L55" Q7Z7F7 1 228106679-228109312 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 249.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027641 Supported "Intracellular and membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA027641: AB_10600825" "unprognostic (4.84e-2)" "unprognostic (3.63e-2)" "unprognostic (6.10e-3)" "unprognostic (3.03e-2)" "unprognostic (7.49e-2)" "unprognostic (2.71e-1)" "unprognostic (2.79e-1)" "unprognostic (1.22e-2)" "unprognostic (4.15e-1)" "prognostic favorable (6.76e-4)" "unprognostic (6.09e-3)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.62e-6)" "unprognostic (5.54e-2)" "unprognostic (8.23e-2)" "unprognostic (1.12e-1)" "unprognostic (1.36e-1)" 42.4 59.7 50.9 14.9 51.8 49.9 43.5 54.3 67.1 38.8 44.4 48.2 24.5 38.2 16.8 41.6 38.5 16.5 75.2 52.0 54.6 57.7 93.2 33.7 21.8 56.0 52.1 38.8 47.2 28.2 52.3 14.2 53.5 48.2 7.8 8.0 43.5 23.7 76.1 42.4 35.6 12.1 52.1 40.3 48.8 41.3 53.6 15.9 43.3 20.6 10.9 40.5 34.6 55.0 59.8 89.3 18.7 34.2 21.5 23.6 75.7 40.0 21.4 43.5 36.6 90.3 56.1 46.2 82.4 27.6 22.5 50.1 18.5 43.6 10.4 39.7 202.3 21.3 68.9 100.9 36.1 56.1 23.3 26.5 35.3 39.1 21.5 17.8 35.5 70.7 54.7 48.6 20.5 69.2 66.5 84.6 63.1 58.6 249.7 58.4 36.7 124.1 27.0 31.4 49.2 49.2 33.1 100.4 75.1 6.4 84.4 50.4 30.7 36.3 41.0 69.7 78.0 42.9 58.3 57.9 60.5 47.9 73.5 62.5 107.6 83.6 86.8 113.5 104.3 121.0 99.2 95.8 107.3 152.1 101.9 108.1 67.9 94.1 96.3 147.8 128.7 104.3 50.9 51.8 54.3 67.1 52.0 54.6 56.0 52.1 53.5 52.1 53.6 55.0 41.6 44.8 59.4 9.1 58.9 76.3 71.5 131.8 44.3 35.9 108.1 112.3 93.1 87.2 82.0 93.8 8.4 142.0 50.4 80.7 236.7 70.2 121.0 44.6 43.2 55.7 78.2 57.4 12.0 94.5 127.2 59.3 37.2 46.1 48.1 53.5 73.2 262.4 124.3 23.5 10.4 105.1 105.8 64.5 128.9 216.3 77.6 54.9 72.9 3.7 98.6 68.7 70.0 4.5 8.3 87.0 69.8 70.0 79.3 74.7 190.3 270.1 73.6 40.7 78.9 46.5 69.8 77.4 80.9 59.4 97.0 110.5 50.6 57.4 94.1 76.1 MRPS14 HSMRPS14 ENSG00000120333 "Mitochondrial ribosomal protein S14" O60783 1 175010789-175023425 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051087 Uncertain Supported "Nuclear membrane,Mitochondria" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" Mitochondria "Nuclear membrane" "HPA051087: AB_2681339" "unprognostic (9.24e-2)" "unprognostic (6.37e-2)" "unprognostic (1.50e-1)" "unprognostic (3.46e-1)" "unprognostic (3.44e-2)" "unprognostic (5.39e-2)" "unprognostic (1.61e-2)" "unprognostic (3.01e-2)" "unprognostic (7.32e-2)" "unprognostic (4.85e-2)" "unprognostic (7.67e-2)" "unprognostic (3.10e-2)" "unprognostic (1.31e-3)" "unprognostic (1.67e-1)" "unprognostic (8.04e-2)" "unprognostic (2.42e-1)" "unprognostic (3.21e-2)" 17.2 20.3 24.9 11.2 26.8 4.5 20.6 26.5 28.3 16.2 20.0 13.4 12.4 17.4 21.7 9.5 15.4 13.9 15.1 23.4 26.9 20.4 19.2 13.2 15.8 26.7 25.8 18.4 14.8 28.0 12.2 13.9 26.7 20.2 15.7 22.5 17.0 16.9 13.0 11.4 11.9 14.9 26.6 14.3 14.1 11.2 25.0 17.5 23.2 14.2 15.1 12.0 9.3 28.3 16.2 12.8 29.5 10.5 32.6 23.4 9.4 13.8 16.8 23.0 23.7 16.7 13.9 20.4 16.5 18.6 10.1 14.0 18.5 16.1 24.3 22.6 25.4 16.8 25.6 19.2 13.8 18.9 14.5 25.6 19.4 13.6 9.4 20.3 19.4 17.4 20.7 17.6 16.2 8.9 20.8 13.7 16.2 30.1 6.7 17.8 15.6 24.4 15.8 12.8 24.8 17.4 20.0 18.3 13.8 23.1 21.7 19.7 15.9 7.8 8.6 16.4 12.5 19.1 17.5 25.1 11.1 17.5 16.6 9.3 15.2 7.7 14.8 15.1 21.2 17.5 15.5 15.8 16.2 17.3 20.8 17.6 5.2 18.2 12.3 14.0 19.0 14.3 24.9 26.8 26.5 28.3 23.4 26.9 26.7 25.8 26.7 26.6 25.0 28.3 29.8 28.9 24.5 5.5 38.4 22.0 52.6 105.9 22.2 17.5 31.6 33.8 78.1 44.3 64.0 55.2 14.6 95.4 26.7 26.4 137.0 69.8 23.8 26.5 35.8 39.1 31.8 46.3 7.8 44.8 107.0 41.4 20.4 26.6 18.3 34.8 33.9 67.2 80.7 1.7 9.4 35.8 103.7 34.7 23.9 12.9 46.6 25.6 49.8 9.4 73.9 46.1 45.3 6.6 10.4 47.7 45.7 42.9 48.7 50.0 35.3 126.1 50.6 22.6 39.5 25.1 66.4 96.9 39.1 36.7 29.3 56.1 28.8 43.0 48.8 52.6 MRPS5 "MRP-S5, S5mt" ENSG00000144029 "Mitochondrial ribosomal protein S5" P82675 2 95085369-95149434 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055765 Approved Supported Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA055765: AB_2682911" "unprognostic (1.18e-1)" "unprognostic (7.79e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (7.98e-7)" "unprognostic (7.51e-3)" "unprognostic (6.30e-3)" "prognostic unfavorable (7.73e-5)" "unprognostic (8.59e-2)" "unprognostic (1.87e-1)" "unprognostic (2.76e-2)" "unprognostic (1.11e-1)" "unprognostic (1.99e-2)" "unprognostic (1.32e-2)" "unprognostic (2.34e-2)" "unprognostic (1.29e-1)" "prognostic favorable (6.36e-4)" "unprognostic (1.25e-1)" 26.0 33.6 5.6 3.8 5.7 7.6 22.3 6.9 7.1 24.4 6.3 34.5 6.9 24.1 4.7 34.5 24.3 3.6 53.6 5.7 5.6 34.6 53.6 24.3 5.5 5.7 5.5 24.9 24.1 6.8 19.9 3.7 5.8 18.5 6.9 5.0 24.7 2.9 71.2 19.4 26.8 5.1 5.1 25.0 30.1 19.5 5.8 6.2 23.8 13.7 5.4 23.7 24.8 6.3 18.8 14.8 8.1 7.8 8.6 10.6 15.3 9.5 4.2 7.1 7.6 28.7 12.9 18.4 7.5 8.4 17.1 11.3 14.0 11.8 13.8 13.0 11.2 11.6 12.3 22.8 11.6 16.5 7.3 10.5 9.3 12.0 12.5 9.0 12.3 10.4 18.0 7.8 10.4 15.1 18.6 17.8 9.0 16.5 13.5 10.5 8.0 21.3 17.4 18.5 12.4 7.8 8.2 17.2 17.6 12.8 7.4 16.0 9.5 10.6 12.9 15.1 15.5 7.6 8.9 14.0 8.8 16.3 9.6 2.5 5.4 3.8 3.6 7.2 4.4 4.5 4.8 4.2 4.8 3.3 4.2 4.4 2.2 3.6 7.4 3.3 5.9 4.2 5.6 5.7 6.9 7.1 5.7 5.6 5.7 5.5 5.8 5.1 5.8 6.3 46.3 80.1 84.6 33.3 52.3 34.8 59.1 112.5 56.9 52.8 42.1 40.5 130.2 58.6 74.4 66.2 50.1 81.8 51.2 68.3 185.9 74.8 68.3 48.5 69.9 48.1 59.4 79.3 31.8 55.4 83.8 53.9 51.0 43.0 40.4 90.7 50.3 129.8 74.1 47.1 29.3 65.0 109.9 51.8 41.2 48.9 51.3 55.3 44.4 7.5 61.5 29.7 44.3 30.7 40.3 50.2 44.2 53.4 69.7 68.1 87.3 131.8 72.3 69.0 39.5 52.2 59.5 80.9 99.1 78.7 32.0 39.4 57.4 60.7 104.5 48.2 MRPS7 "MRP-S, RP-S7, RPMS7" ENSG00000125445 "Mitochondrial ribosomal protein S7" Q9Y2R9 17 75261674-75266376 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 454.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022522, HPA023007" Supported Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA022522: AB_1854131, HPA023007: AB_1854132" "unprognostic (1.24e-1)" "unprognostic (4.74e-2)" "prognostic favorable (1.12e-4)" "unprognostic (5.82e-3)" "unprognostic (3.62e-2)" "unprognostic (5.05e-3)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.32e-1)" "unprognostic (1.04e-1)" "unprognostic (4.95e-2)" "unprognostic (8.56e-3)" "unprognostic (1.03e-1)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (8.56e-2)" "unprognostic (1.76e-1)" "unprognostic (4.15e-1)" 44.3 58.4 55.5 38.1 55.9 32.9 41.2 60.0 61.9 28.7 59.0 49.9 48.9 28.3 24.4 58.5 39.2 27.1 129.0 55.1 59.3 66.1 64.6 32.4 41.3 57.2 57.5 29.2 39.0 76.6 36.0 40.8 57.6 34.1 48.2 47.3 41.1 35.7 201.3 32.6 40.0 33.8 57.8 39.5 47.5 29.9 59.8 33.6 35.9 212.3 43.6 42.6 35.0 56.3 113.8 188.6 78.8 57.6 63.9 35.7 139.4 73.3 60.9 137.4 101.1 209.8 93.5 96.4 66.4 79.8 91.4 104.5 122.3 135.8 82.2 50.8 173.5 131.8 133.6 201.3 62.5 134.3 69.6 60.0 131.8 108.6 109.6 69.2 177.3 117.8 130.1 93.3 91.1 203.5 151.8 104.7 85.4 157.7 176.2 100.7 229.5 145.2 128.4 124.6 135.8 122.8 93.8 249.9 150.0 83.9 188.4 108.7 72.2 124.0 125.3 68.2 155.7 97.9 61.5 106.6 89.5 88.3 96.9 43.2 155.1 48.2 115.7 161.6 124.2 140.2 112.0 126.0 172.0 128.1 128.6 120.7 11.0 130.5 138.5 164.9 141.6 236.0 55.5 55.9 60.0 61.9 55.1 59.3 57.2 57.5 57.6 57.8 59.8 56.3 44.1 51.3 48.3 12.1 69.3 39.5 75.1 148.1 37.0 65.8 56.5 63.0 77.8 70.1 74.3 57.0 98.0 192.9 63.3 94.1 230.9 112.9 139.2 50.9 43.2 55.6 47.5 61.4 11.8 104.1 175.3 50.2 55.5 43.5 39.3 68.6 45.3 91.7 148.8 47.1 14.0 84.3 77.3 60.0 35.6 454.3 48.4 52.6 42.7 3.7 107.0 85.6 73.2 9.5 11.3 89.8 69.3 39.9 87.7 85.3 129.2 219.3 81.0 114.4 59.2 40.8 73.0 60.5 68.5 68.5 41.9 137.9 53.8 110.0 133.8 77.4 MS4A14 "DKFZp434H092, FLJ32856, MS4A16, NYD-SP21" ENSG00000166928 "Membrane spanning 4-domains A14" Q96JA4 11 60378530-60417756 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 73.0" "Group enriched" "Detected in some" 44 "Early spermatids: 262.3;Late spermatids: 672.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.5;non-classical monocyte: 8.0" "Lineage enriched" "Detected in many" 5 "monocytes: 8.0" "Cell line enriched" "Detected in single" 23 "THP-1: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA058973 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA058973: " "unprognostic (1.78e-1)" "unprognostic (1.76e-1)" "unprognostic (5.75e-2)" "unprognostic (1.77e-1)" "unprognostic (1.27e-1)" "unprognostic (1.79e-2)" "unprognostic (1.24e-1)" "unprognostic (3.45e-2)" "unprognostic (4.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.77e-1)" "unprognostic (2.14e-1)" "unprognostic (4.50e-6)" "unprognostic (3.73e-2)" "unprognostic (7.16e-3)" "unprognostic (8.40e-2)" "unprognostic (7.11e-2)" 5.1 3.7 6.2 3.5 5.6 0.6 3.6 5.8 8.8 1.2 7.5 2.7 0.7 0.9 0.6 0.9 1.3 0.9 2.6 5.8 6.3 1.8 2.0 11.9 1.3 7.7 6.8 0.7 1.3 0.3 1.5 2.4 7.2 1.8 1.1 0.4 1.9 0.5 0.9 0.9 2.7 1.2 6.0 10.4 1.2 73.0 8.5 0.3 1.5 0.3 1.9 2.0 1.2 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 3.4 0.0 0.0 5.5 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.9 6.2 5.6 5.8 8.8 5.8 6.3 7.7 6.8 7.2 6.0 8.5 8.0 0.2 0.0 1.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 262.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 7.3 5.5 672.0 4.1 10.4 0.0 3.7 5.7 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.7 0.0 6.6 0.1 0.0 6.5 3.4 0.0 0.3 0.1 0.1 0.0 0.0 0.0 MS4A3 "CD20L, HTM4" ENSG00000149516 "Membrane spanning 4-domains A3" Q96HJ5 11 60056587-60071115 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 93 "bone marrow: 420.2" "Cell type enriched" "Detected in some" 5 "Erythroid cells: 19.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 1478 "basophil: 2686.3" "Lineage enriched" "Detected in single" 4507 "granulocytes: 2686.3" "Cell line enhanced" "Detected in some" "HEL: 48.9;K-562: 94.2;NB-4: 109.8;THP-1: 319.0;U-937: 126.2" "Not detected" "Not detected" HPA019210 Supported Approved "Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA019210: AB_1854134" "unprognostic (6.37e-3)" "unprognostic (1.25e-1)" "unprognostic (2.67e-1)" "unprognostic (3.77e-1)" 0.1 0.0 0.0 0.3 0.0 420.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 4.5 0.0 0.5 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 48.9 0.0 0.0 0.0 17.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.2 0.0 0.0 0.0 0.0 109.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 319.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 126.2 0.0 2686.3 0.1 1.8 0.1 0.1 0.3 0.2 0.4 0.0 0.3 0.2 0.2 0.4 0.9 0.1 0.5 0.2 0.1 8.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 19.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.3 0.0 0.0 0.8 0.0 3.6 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 MS4A5 CD20L2 ENSG00000166930 "Membrane spanning 4-domains A5" Q9H3V2 11 60429572-60455214 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 167 "testis: 44.5" "Group enriched" "Detected in some" 66 "Early spermatids: 700.0;Late spermatids: 1017.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043732 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "HPA043732: AB_10959759" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 700.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1017.8 5.6 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 5.3 0.0 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.0 13.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MSANTD1 "C4orf44, LOC345222" ENSG00000188981 "Myb/SANT DNA binding domain containing 1" Q6ZTZ1 4 3244369-3271738 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 4.5;testis: 3.8" "Group enriched" "Detected in some" 4 "Early spermatids: 38.5;Late spermatids: 28.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "unprognostic (7.10e-2)" "unprognostic (4.31e-1)" "unprognostic (3.03e-3)" "unprognostic (1.28e-1)" "unprognostic (2.59e-1)" "unprognostic (1.16e-3)" "unprognostic (2.04e-2)" "unprognostic (4.67e-2)" "unprognostic (3.99e-1)" "unprognostic (5.50e-2)" "unprognostic (2.34e-3)" "unprognostic (6.36e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-2)" "unprognostic (8.57e-2)" "unprognostic (5.96e-2)" "unprognostic (1.24e-1)" 0.3 0.2 2.4 0.1 2.9 0.1 0.3 0.8 2.3 0.5 0.0 0.4 0.1 0.3 0.2 0.4 0.3 0.0 0.3 2.2 4.4 0.5 0.5 0.5 0.1 0.9 1.4 0.4 1.0 0.0 1.1 0.0 1.0 0.6 0.0 0.7 0.3 0.0 0.7 0.3 0.4 0.0 0.0 0.8 0.8 3.8 4.5 0.0 1.0 0.0 0.0 0.4 0.4 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.3 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.9 0.8 2.3 2.2 4.4 0.9 1.4 1.0 0.0 4.5 0.8 0.5 0.0 0.0 1.3 0.1 1.0 0.1 0.1 0.0 2.4 0.5 0.3 1.4 0.0 0.1 0.0 4.2 0.1 0.5 0.1 1.9 0.0 38.5 0.7 0.3 0.3 0.0 0.0 3.0 6.8 0.5 0.2 0.0 0.8 0.0 2.2 0.0 0.2 0.3 1.7 3.0 0.2 0.0 0.0 0.7 28.4 0.0 0.3 0.0 1.9 0.0 0.8 1.0 1.0 1.8 0.3 1.1 0.4 0.0 0.2 0.0 0.3 0.2 2.0 0.0 0.4 0.3 4.5 1.3 0.4 0.3 0.0 0.2 0.1 0.1 0.1 MSH3 "DUP, MRP1" ENSG00000113318 "MutS homolog 3" P20585 5 80654652-80876815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 95.1;Inhibitory neurons: 98.9;Oligodendrocytes: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036081 Approved "Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear bodies" "HPA036081: AB_10673229" "unprognostic (1.91e-1)" "unprognostic (7.61e-2)" "prognostic favorable (5.90e-5)" "unprognostic (2.95e-2)" "unprognostic (1.89e-1)" "unprognostic (6.41e-2)" "unprognostic (1.81e-1)" "unprognostic (8.70e-2)" "unprognostic (3.17e-2)" "unprognostic (2.62e-2)" "unprognostic (2.63e-1)" "unprognostic (3.91e-1)" "prognostic favorable (1.77e-4)" "unprognostic (5.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" 9.4 4.6 1.8 4.3 2.4 5.0 5.5 1.6 2.0 6.6 1.5 6.0 6.0 5.2 5.3 5.0 7.0 5.7 4.9 1.7 2.0 12.5 11.4 4.2 4.9 1.7 2.0 5.3 5.2 8.8 3.3 4.3 1.7 5.2 6.2 3.7 4.5 5.2 5.1 5.1 5.6 5.1 2.2 4.1 5.0 3.9 2.5 7.1 10.8 4.7 6.1 6.3 3.9 2.0 12.4 15.0 11.7 13.1 6.6 12.3 16.6 12.2 11.8 13.6 16.7 10.0 15.6 22.2 14.0 15.3 12.8 10.4 15.6 20.5 17.3 14.2 13.9 8.4 13.4 9.9 6.8 9.9 8.5 10.9 9.5 15.8 16.6 13.8 12.9 7.9 12.1 12.9 16.1 11.9 19.0 4.7 9.0 4.8 7.7 13.2 24.2 16.4 15.2 13.0 11.6 13.9 10.4 11.5 13.0 14.4 15.2 9.4 12.4 7.8 9.5 6.2 23.0 8.7 15.6 21.6 12.2 16.8 10.2 0.7 2.9 1.9 3.3 3.4 3.8 3.4 3.5 3.6 3.3 2.2 2.6 2.6 1.7 3.1 4.6 2.8 4.8 2.4 1.8 2.4 1.6 2.0 1.7 2.0 1.7 2.0 1.7 2.2 2.5 2.0 16.7 35.3 9.3 66.9 18.1 10.5 12.3 12.4 12.5 25.8 19.4 12.8 17.6 8.6 14.3 14.7 14.6 18.9 18.7 18.2 15.6 12.4 14.6 28.4 20.2 12.0 14.5 17.0 95.1 10.3 12.9 15.9 31.6 18.9 8.2 19.9 10.0 20.1 11.5 21.9 98.9 13.2 8.2 13.0 7.0 17.2 13.7 16.3 3.6 72.1 19.9 22.5 19.6 71.9 92.3 10.6 9.6 25.9 22.0 6.5 16.8 43.6 65.4 28.3 19.7 20.2 14.7 24.7 25.5 22.3 10.1 13.1 25.4 14.7 17.4 10.7 MSI2 ENSG00000153944 "Musashi RNA binding protein 2" Q96DH6 17 57255851-57684689 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 830.2;Cone photoreceptor cells: 754.8;Rod photoreceptor cells: 500.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "REH: 184.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022300, HPA068990" Approved Supported Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 14: REH - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "CAB022300: , HPA068990: " "unprognostic (4.73e-2)" "unprognostic (2.28e-1)" "unprognostic (3.42e-2)" "unprognostic (1.26e-1)" "unprognostic (1.12e-1)" "unprognostic (1.08e-1)" "unprognostic (4.20e-2)" "unprognostic (2.20e-2)" "unprognostic (4.89e-2)" "unprognostic (2.96e-1)" "unprognostic (4.17e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.22e-8)" "prognostic favorable (2.00e-4)" "unprognostic (4.87e-2)" "unprognostic (1.57e-1)" "unprognostic (2.72e-3)" 7.5 69.1 52.2 13.2 52.8 20.2 18.9 53.0 43.4 12.1 105.7 14.1 10.3 14.0 49.9 9.3 22.9 18.3 33.4 42.0 74.6 36.8 7.5 8.3 22.2 82.5 88.6 46.4 12.8 88.6 44.7 22.6 63.4 21.5 15.6 126.0 17.0 21.0 60.7 8.0 11.7 7.6 63.5 17.2 16.6 15.4 58.8 46.5 25.6 43.4 19.6 19.8 8.2 56.0 11.8 18.8 79.0 28.6 7.7 7.8 53.9 13.7 16.4 16.8 10.1 23.6 20.4 56.9 47.1 9.4 13.1 11.8 50.6 18.1 34.8 77.1 31.7 26.2 46.5 58.7 17.8 28.0 23.9 10.4 24.3 2.4 29.9 24.1 19.3 46.6 52.5 42.3 67.6 27.1 136.8 7.2 26.0 64.0 33.2 184.3 109.8 45.5 46.2 84.0 76.6 154.5 22.1 22.9 63.7 33.8 36.9 21.0 22.4 11.2 27.2 9.2 23.0 57.3 51.7 68.8 29.9 16.7 70.2 2.7 0.1 1.9 0.7 0.1 0.6 0.7 0.8 0.7 0.2 0.4 0.6 0.7 0.1 0.8 0.8 1.1 1.6 0.2 52.2 52.8 53.0 43.4 42.0 74.6 82.5 88.6 63.4 63.5 58.8 56.0 20.5 6.4 28.7 830.2 50.5 24.0 74.9 54.5 34.7 202.1 53.2 33.9 99.1 54.3 42.3 75.4 754.8 117.9 37.5 29.5 123.3 49.3 15.3 150.2 30.8 28.1 98.2 35.5 67.6 14.2 25.9 34.2 34.1 70.8 41.8 178.7 29.6 31.5 20.4 294.4 175.5 51.8 109.9 12.6 16.4 27.2 64.7 20.1 39.2 158.3 13.2 220.6 22.6 249.3 111.6 12.8 24.3 77.5 88.8 74.7 11.6 51.2 106.0 500.1 13.1 42.3 30.6 3.1 7.6 28.2 16.1 149.3 50.6 113.5 37.8 92.4 MSLN "CAK1, MPF" ENSG00000102854 Mesothelin Q13421 16 760734-768865 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 93.4;fallopian tube: 278.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 189.1;Alveolar cells type 2: 85.6;Club cells: 121.9;Glandular and luminal cells: 57.1;Paneth cells: 214.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 343.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.9" "Group enriched" "Detected in many" 39 "dendritic cells: 5.9;monocytes: 1.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 513.4;EFO-21: 77.4;HeLa: 173.4;hTCEpi: 111.5;OE19: 96.4" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 9 "spinal cord: 1.7" "CAB002216, HPA017172" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 17000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "CAB002216: AB_563874, HPA017172: AB_1853819" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (2.06e-2)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (3.95e-2)" "unprognostic (2.46e-1)" "unprognostic (9.47e-2)" "unprognostic (8.57e-2)" "unprognostic (4.69e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.63e-1)" "prognostic favorable (5.91e-4)" "unprognostic (2.00e-2)" "unprognostic (1.60e-1)" "unprognostic (2.14e-2)" "unprognostic (3.35e-2)" 93.4 0.2 0.7 1.1 1.0 3.2 0.5 0.6 1.5 15.9 0.3 8.9 7.1 6.2 24.1 7.1 278.2 16.4 8.4 0.7 0.8 6.5 0.2 71.8 0.2 1.9 1.2 3.7 0.9 0.1 0.7 2.7 1.3 3.8 4.0 0.7 39.3 9.9 0.0 1.4 2.9 3.4 1.0 0.4 13.0 1.1 1.2 0.8 0.2 0.0 27.2 2.9 2.9 1.0 0.4 2.1 0.0 1.0 0.0 0.0 2.3 0.3 7.7 8.7 2.0 7.4 513.4 0.0 77.4 0.7 0.1 1.3 0.0 0.7 0.7 0.2 0.3 0.0 173.4 5.9 4.4 0.2 0.1 0.0 111.5 0.0 2.0 7.8 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.1 0.6 96.4 0.8 0.2 0.2 0.6 2.4 0.1 0.1 0.0 29.7 0.1 0.0 0.1 0.7 0.0 0.0 0.4 12.1 0.1 0.0 0.3 0.3 0.4 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.3 0.7 1.0 0.6 1.5 0.7 0.8 1.9 1.2 1.3 1.0 1.2 1.0 0.0 189.1 85.6 0.0 0.0 0.3 3.0 49.0 0.0 1.4 0.3 0.3 1.6 52.9 121.9 25.8 0.0 0.2 0.0 4.1 0.0 9.3 1.6 35.8 3.3 0.7 3.0 0.0 0.0 0.9 0.0 4.6 0.0 57.1 0.0 0.0 0.4 0.1 2.9 0.0 0.0 1.6 22.4 1.0 1.9 7.4 4.7 3.7 1.8 1.0 4.4 0.0 0.0 0.0 0.0 33.0 214.4 0.0 1.4 3.3 1.7 0.1 54.2 0.6 0.0 0.0 2.8 0.6 0.7 0.5 0.1 0.1 1.3 0.0 3.1 50.8 MSMB "IGBF, MSP, MSPB, PN44, PRPS, PSP, PSP-94, PSP57, PSP94" ENSG00000263639 "Microseminoprotein beta" P08118 10 46033307-46048180 "Cancer-related genes, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "prostate: 9384.0" "Cell type enriched" "Detected in many" 4 "Prostatic glandular cells: 10715.4" "Cancer enriched" "Detected in many" 42 "prostate cancer: 3435.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 25.6;NB-4: 21.6;RPMI-8226: 11.3;SH-SY5Y: 6.1;SK-BR-3: 5.9;U-2197: 12.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB026357, HPA051257" Enhanced "Secreted in male reproductive system" NA NA 6000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "CAB026357: , HPA051257: AB_2681410" "unprognostic (6.47e-2)" "unprognostic (7.21e-3)" "unprognostic (1.37e-2)" "unprognostic (8.18e-3)" "unprognostic (4.28e-3)" "unprognostic (9.24e-3)" "unprognostic (1.66e-1)" "unprognostic (8.66e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (2.01e-1)" "unprognostic (7.04e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.19e-4)" 5.1 4.5 0.0 3.0 0.0 0.1 20.5 0.0 0.0 3.2 0.0 2.8 10.3 0.3 45.1 12.3 4.6 3.0 0.5 0.0 0.0 1.8 1.8 29.9 0.2 0.0 0.0 0.3 2.3 0.2 0.5 0.6 0.0 9384.0 0.1 0.0 31.9 0.6 0.4 39.7 2.3 0.0 0.0 0.7 552.3 10.1 0.0 1.0 0.7 0.0 10.0 7.2 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 25.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 21.6 0.2 0.0 0.0 0.0 0.0 11.3 0.0 1.6 1.0 6.1 0.0 5.9 0.0 0.2 0.4 0.0 0.0 0.0 0.0 12.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.3 0.0 195.9 586.4 0.0 0.0 6.4 1.3 0.0 4.3 2203.2 0.0 0.0 2.1 0.1 0.3 0.0 0.1 48.9 0.6 0.0 10.7 0.0 0.0 0.1 0.2 0.4 9.5 404.2 0.2 1.3 0.0 0.0 1.2 0.2 0.0 0.0 0.8 419.1 0.0 0.0 78.8 0.3 30.5 3.6 0.0 0.0 0.0 0.0 0.0 0.0 1.8 29.6 0.0 0.8 10715.4 0.3 0.0 570.6 0.0 0.0 0.0 271.0 0.5 1.4 0.0 0.4 1.5 14.3 0.0 0.1 192.4 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 86.0;liver: 64.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 625.8;Inhibitory neurons: 318.6;Oligodendrocyte precursor cells: 268.9;Proximal tubular cells: 666.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 28.4" "Immune cell enhanced" "Detected in some" "eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 12.3" "Low region specificity" "Detected in all" "HPA023804, HPA075766" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" No No 55000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "Plasma membrane, Actin filaments" "HPA023804: AB_1853826, HPA075766: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 17.0 20.4 2.2 1.1 3.0 13.5 16.1 28.4 5.4 9.1 0.0 13.9 1.1 10.7 0.1 11.6 7.4 0.4 29.0 3.8 0.0 86.0 64.0 12.2 0.6 0.0 0.4 6.4 14.5 0.7 9.2 0.8 1.8 9.2 0.6 0.6 10.5 1.0 14.5 9.5 20.1 0.8 0.0 18.6 14.2 15.2 0.3 1.5 9.6 1.3 0.6 11.6 8.2 2.8 0.1 0.9 1.3 4.3 1.2 1.4 0.5 2.5 0.2 0.3 1.7 0.6 2.1 0.0 0.6 2.5 5.8 2.3 0.4 0.1 1.3 0.2 0.0 0.3 1.5 2.2 4.3 0.8 12.3 0.4 3.2 0.3 0.0 1.4 0.6 0.3 0.4 0.2 4.9 0.1 0.0 0.3 0.6 3.3 0.8 1.6 1.3 2.0 1.1 1.1 2.5 1.5 4.6 0.2 0.5 0.4 2.3 2.8 2.6 1.7 2.0 0.4 1.2 0.2 0.1 0.7 4.8 0.8 3.1 0.5 1.9 5.6 0.4 1.2 0.3 0.6 0.4 0.3 1.2 0.1 0.3 0.2 2.2 0.7 0.9 0.2 0.3 0.2 2.2 3.0 28.4 5.4 3.8 0.0 0.0 0.4 1.8 0.0 0.3 2.8 44.1 0.0 7.4 152.8 21.4 16.4 29.3 10.8 14.2 10.1 21.2 21.8 21.6 25.8 7.2 25.8 31.3 7.7 12.4 26.4 92.0 32.3 80.6 13.6 8.7 30.3 9.6 3.4 625.8 47.1 4.6 13.1 14.8 11.8 80.7 13.7 19.6 97.2 47.0 16.8 318.6 20.8 4.1 33.6 48.3 167.9 9.3 38.0 30.2 85.3 22.3 14.6 11.3 268.9 60.7 51.1 37.8 9.8 16.2 33.8 195.5 666.1 5.6 6.2 13.1 11.3 16.9 39.3 26.5 20.1 14.1 8.3 18.0 14.1 24.5 31.1 MSRB2 "CBS-1, CBS1, CGI-131, MSRB, PILB" ENSG00000148450 "Methionine sulfoxide reductase B2" Q9Y3D2 10 23095579-23122013 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 269.1;Proximal tubular cells: 463.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027933 Enhanced "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA027933: AB_10601867" "unprognostic (4.89e-2)" "unprognostic (2.76e-2)" "unprognostic (7.14e-3)" "unprognostic (3.47e-3)" "unprognostic (4.51e-1)" "unprognostic (9.26e-3)" "unprognostic (1.62e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (6.07e-3)" "unprognostic (3.47e-2)" "unprognostic (1.08e-2)" "unprognostic (2.03e-1)" "unprognostic (1.82e-2)" "unprognostic (6.74e-2)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" 16.2 17.3 29.0 6.6 30.8 7.7 11.0 29.5 40.5 13.2 26.8 22.7 9.4 15.8 16.8 10.8 17.6 7.7 61.6 29.5 32.2 19.0 31.0 9.8 3.9 30.4 30.9 11.9 5.4 23.1 14.4 8.2 30.5 14.3 11.4 13.1 9.1 19.5 42.2 5.5 11.9 16.3 29.1 9.3 11.4 3.9 30.8 8.4 14.1 51.7 4.1 17.1 11.0 29.4 7.3 10.4 19.0 11.6 19.3 17.3 5.7 11.5 6.4 7.2 8.3 7.2 15.5 5.9 10.0 24.6 10.9 4.6 6.3 8.6 5.9 40.3 7.0 4.3 17.7 4.1 27.2 0.9 5.0 22.2 14.3 8.4 2.0 15.7 10.4 11.5 5.9 10.3 16.0 21.9 7.0 5.5 10.5 41.4 6.0 8.0 10.9 1.5 9.1 2.8 3.8 26.1 14.2 12.4 23.9 15.9 8.4 17.1 7.7 6.2 5.8 14.0 6.9 13.3 4.4 0.2 8.8 12.7 5.3 0.9 1.4 2.3 0.3 1.1 0.3 0.2 0.3 0.2 0.8 0.0 0.6 0.4 3.4 0.2 0.8 1.6 0.4 0.2 29.0 30.8 29.5 40.5 29.5 32.2 30.4 30.9 30.5 29.1 30.8 29.4 29.0 0.0 16.4 27.1 11.4 18.2 52.1 33.1 59.2 68.2 69.6 79.1 269.1 80.1 21.1 90.1 22.9 116.1 10.6 86.7 176.1 130.4 1.4 49.3 71.6 34.4 55.7 30.7 9.5 63.4 61.2 70.7 23.4 46.5 29.2 114.0 42.1 195.4 109.6 112.7 16.9 54.8 26.4 70.5 25.1 4.4 49.7 54.2 72.9 11.2 29.7 126.6 7.2 14.6 26.1 90.3 79.6 62.4 24.7 34.9 80.8 463.9 24.3 57.5 59.2 52.6 71.6 4.4 7.7 66.7 17.5 69.6 13.5 60.9 71.0 54.3 MSRB3 "DFNB74, DKFZp686C1178, FLJ36866" ENSG00000174099 "Methionine sulfoxide reductase B3" Q8IXL7 12 65278643-65491430 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 2801.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 41.6" "Lineage enhanced" "Detected in many" "granulocytes: 41.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 126.1;hTERT-RPE1: 110.6;U-937: 106.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014432 Enhanced "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 32: U-937 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA014432: AB_1854146" "unprognostic (1.40e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (2.86e-3)" "unprognostic (1.94e-1)" "unprognostic (2.74e-2)" "unprognostic (1.74e-2)" "unprognostic (2.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-2)" "unprognostic (5.33e-2)" "unprognostic (8.28e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (8.85e-8)" "unprognostic (3.29e-3)" "unprognostic (7.80e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (2.17e-4)" 44.9 10.7 12.9 20.9 13.6 21.2 26.3 12.5 12.8 29.5 18.8 108.0 11.9 85.8 20.1 63.0 41.4 33.2 90.8 11.9 18.3 10.1 3.8 30.6 5.7 15.9 15.2 16.9 5.8 3.2 6.8 25.2 13.8 52.7 27.8 12.5 10.8 103.0 104.0 9.7 25.6 123.9 14.6 13.6 36.2 5.8 18.2 4.1 14.5 69.2 3.9 60.9 23.7 11.8 8.8 19.2 16.4 75.9 71.6 63.0 0.5 87.0 92.9 33.2 19.8 0.7 1.0 0.0 18.3 126.1 10.5 1.9 7.7 22.1 30.0 0.2 15.9 0.0 16.7 0.9 46.6 47.1 0.3 33.4 11.9 28.1 39.0 110.6 68.2 0.1 0.3 0.3 76.8 2.9 0.0 11.0 5.4 0.2 10.4 0.2 22.0 0.5 7.5 1.0 0.4 7.9 30.0 1.8 21.9 16.8 14.1 44.5 78.9 42.3 22.8 19.5 34.2 8.0 6.7 0.2 11.5 106.7 26.9 15.0 0.6 41.6 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.2 6.8 8.3 0.4 10.8 0.1 1.4 12.9 13.6 12.5 12.8 11.9 18.3 15.9 15.2 13.8 14.6 18.2 11.8 55.3 12.8 3.4 76.7 0.8 6.4 16.4 11.4 4.0 22.7 2.2 45.3 2801.7 4.3 1.2 3.7 0.0 0.4 8.3 0.0 0.0 9.3 5.7 0.9 16.7 154.2 0.0 17.4 37.1 1.0 0.4 108.8 1.1 0.4 2.5 7.4 28.2 0.2 0.5 21.9 56.6 0.0 0.0 0.0 13.7 2.2 12.5 4.0 10.6 62.8 1.6 44.4 2.1 37.7 1.4 1.6 0.0 116.6 0.3 14.8 0.0 0.4 6.8 10.6 105.2 37.7 218.7 4.2 4.7 0.8 4.5 0.7 2.4 10.3 0.0 2.9 MST1 "D3F15S2, DNF15S2, HGFL, MSP, NF15S2" ENSG00000173531 "Macrophage stimulating 1" 3 49683947-49689501 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 10 "liver: 927.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 362.8" "Cancer enriched" "Detected in many" 7 "liver cancer: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 84.6;NB-4: 17.3;U-266/70: 21.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024036 Approved "Secreted to blood" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA024036: AB_1854147" "unprognostic (5.13e-3)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "unprognostic (1.16e-2)" "unprognostic (9.42e-3)" "unprognostic (8.24e-2)" "unprognostic (2.97e-1)" "prognostic favorable (7.14e-4)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" 29.3 28.0 8.1 1.0 8.3 6.3 8.2 8.8 14.0 12.6 8.1 5.1 50.6 8.9 11.3 7.3 10.5 7.4 4.9 8.1 8.4 96.9 927.9 5.9 3.6 8.4 8.4 12.5 16.4 9.4 29.3 5.8 8.3 12.9 2.1 5.3 8.1 5.1 3.6 14.8 31.1 2.1 8.1 13.9 8.8 34.9 8.2 2.2 36.4 2.9 1.7 6.0 6.9 8.3 0.2 0.4 1.2 2.0 3.7 7.6 3.7 1.1 1.4 0.6 0.8 3.9 1.2 0.3 2.6 1.3 0.5 0.8 0.6 1.5 0.6 1.3 0.7 0.6 2.6 84.6 5.8 0.0 1.6 10.2 2.6 0.7 2.1 14.1 1.4 3.5 0.7 9.9 1.9 0.6 0.5 17.3 0.2 1.1 1.0 0.4 0.5 2.2 4.2 0.6 0.2 2.8 0.0 1.6 0.4 2.5 1.5 5.7 0.9 1.9 0.6 0.1 0.2 21.8 2.9 0.5 2.2 3.2 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.1 8.3 8.8 14.0 8.1 8.4 8.4 8.4 8.3 8.1 8.2 8.3 3.1 6.4 3.9 10.1 3.5 2.9 4.6 5.8 6.8 8.2 6.1 10.2 2.2 45.8 5.4 27.6 8.4 4.8 1.0 5.1 62.6 6.9 7.6 2.3 3.5 3.4 8.3 29.7 1.1 3.9 19.7 5.2 9.2 3.2 1.3 36.9 10.0 362.8 1.4 1.7 2.0 8.9 6.1 10.7 1.4 2.6 3.1 1.2 3.6 2.8 0.1 8.9 0.0 3.0 2.9 2.1 7.2 1.9 1.6 1.3 57.0 61.9 6.7 6.9 0.0 2.3 10.9 21.8 9.2 2.6 4.7 5.1 2.1 22.8 13.7 3.4 MSTN GDF8 ENSG00000138379 Myostatin O14793 2 190055700-190062729 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 10.1;tongue: 15.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.7;Cone photoreceptor cells: 4.2;Early spermatids: 17.8;Late spermatids: 4.2;Muller glia cells: 19.1" "Cancer enriched" "Detected in some" 9 "glioma: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "LHCN-M2: 25.9;RH-30: 52.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009963 Approved "Secreted in other tissues" NA NA 7600000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB009963: AB_2148798" "unprognostic (8.45e-2)" "unprognostic (2.84e-2)" "unprognostic (3.52e-2)" "unprognostic (2.54e-1)" "prognostic favorable (2.86e-4)" "unprognostic (7.59e-3)" "unprognostic (2.95e-1)" "unprognostic (4.09e-2)" "unprognostic (1.91e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-3)" "unprognostic (7.72e-3)" "unprognostic (1.12e-4)" "unprognostic (1.06e-1)" "unprognostic (3.94e-1)" "unprognostic (6.53e-2)" "unprognostic (5.67e-4)" 0.4 0.9 0.6 0.0 0.6 0.0 0.3 0.7 0.9 1.2 0.1 0.6 0.2 0.8 0.5 1.1 0.3 0.1 0.3 0.7 0.5 0.5 0.1 0.2 0.0 0.6 0.6 0.4 0.2 0.0 0.6 0.0 0.6 0.4 0.4 3.1 0.4 0.1 10.1 0.5 0.2 0.3 0.4 0.2 0.2 0.3 0.5 0.0 0.4 15.3 0.0 0.2 0.5 0.5 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.9 0.7 0.5 0.6 0.6 0.6 0.4 0.5 0.5 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.1 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 17.8 0.1 0.1 0.1 0.0 0.0 1.4 0.2 0.0 1.4 0.0 0.0 0.0 0.4 0.4 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 0.0 0.0 19.1 0.0 0.5 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 2.0 0.0 0.7 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MT1B "MT1, MT1Q" ENSG00000169688 "Metallothionein 1B" P07438 16 56651886-56653204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "liver: 22.9" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 4.4;Hepatocytes: 12.8;Proximal enterocytes: 3.2;Proximal tubular cells: 6.7" "Cancer enriched" "Detected in single" 209 "liver cancer: 57.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.66e-1)" 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.9 0.0 0.0 0.7 12.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 3.2 6.7 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 MT1E "MT1, MTD" ENSG00000169715 "Metallothionein 1E" P04732 16 56625475-56627112 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1787.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 4001.6;Paneth cells: 4625.0;Proximal enterocytes: 5720.1;Proximal tubular cells: 8933.3;Undifferentiated cells: 2966.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 5.8;T-cells: 20.6" "Cell line enhanced" "Detected in many" "HBEC3-KT: 1095.1;LHCN-M2: 827.5;RPTEC TERT1: 946.2;U-2 OS: 527.7" HPA041152 Approved Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA041152: AB_2732490" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (3.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.77e-2)" "unprognostic (1.19e-2)" "unprognostic (3.63e-1)" "unprognostic (9.80e-2)" "unprognostic (7.85e-2)" "unprognostic (3.45e-2)" "unprognostic (2.78e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (5.06e-5)" "unprognostic (1.86e-1)" "unprognostic (9.53e-2)" "unprognostic (1.97e-1)" "unprognostic (3.78e-2)" 927.5 339.2 364.4 52.2 378.0 2.8 264.0 393.5 510.1 109.2 317.9 261.4 105.1 60.3 12.6 135.4 299.6 40.9 128.8 354.1 378.2 497.9 1787.5 230.3 11.7 376.7 390.6 72.4 537.3 16.3 53.3 19.1 394.6 240.3 189.3 36.8 94.7 20.6 323.0 192.4 357.7 85.5 366.2 30.3 584.7 11.5 400.8 4.0 382.6 92.5 8.0 89.1 140.9 355.9 102.2 0.0 0.0 0.0 154.5 177.0 1.6 263.8 278.6 70.7 82.1 0.9 133.0 0.0 20.3 91.6 10.7 216.7 241.2 1095.1 96.8 102.7 0.0 4.1 139.4 17.5 69.2 0.6 0.6 122.7 362.4 185.5 211.6 426.7 43.5 0.1 0.2 0.7 827.5 0.2 0.4 67.3 94.3 0.0 1.1 0.3 0.0 2.9 946.2 0.0 14.2 0.7 0.7 0.2 1.0 17.4 0.5 124.1 108.6 0.4 527.7 82.5 51.5 0.5 1.9 2.8 296.9 170.2 0.9 0.0 2.9 0.0 14.7 2.1 5.0 0.5 8.2 20.3 5.8 0.0 3.7 14.7 0.1 0.2 1.8 0.3 20.6 3.8 364.4 378.0 393.5 510.1 354.1 378.2 376.7 390.6 394.6 366.2 400.8 355.9 1237.9 394.2 158.2 83.9 59.6 178.6 240.1 86.9 306.2 0.0 214.2 311.0 106.8 589.0 168.4 496.6 0.0 18.4 32.7 2403.7 1402.9 392.8 1.8 710.8 161.7 210.0 241.9 186.9 0.2 193.7 908.6 522.8 880.2 1646.2 28.5 184.3 222.8 4001.6 34.9 0.0 0.2 2467.0 22.4 110.6 29.0 4.6 149.5 121.0 110.3 8.4 61.9 0.0 1.0 7.5 2.0 314.3 4625.0 51.1 20.6 998.6 5720.1 8933.3 137.6 0.0 216.9 818.8 513.7 3.2 3.7 286.4 148.0 79.8 96.0 14.7 2966.9 84.3 MT1G "MT1, MT1K" ENSG00000125144 "Metallothionein 1G" P13640 16 56666730-56668065 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 3543.0;liver: 6959.4;thyroid gland: 2886.6" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 77919.3" "Group enriched" "Detected in all" 4 "liver cancer: 320.1;ovarian cancer: 106.9;prostate cancer: 103.9;testis cancer: 269.9;thyroid cancer: 369.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "U-937: 1103.8" "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.62e-1)" "unprognostic (4.21e-1)" "unprognostic (2.77e-2)" "unprognostic (3.15e-1)" "unprognostic (1.32e-2)" "unprognostic (1.73e-3)" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (5.97e-2)" "unprognostic (2.49e-2)" "unprognostic (4.21e-1)" "prognostic unfavorable (1.67e-7)" "unprognostic (1.42e-1)" "unprognostic (3.50e-2)" "unprognostic (7.92e-2)" "unprognostic (2.26e-2)" 250.2 21.5 434.9 105.8 515.9 2.9 28.1 469.3 912.6 21.9 396.7 821.1 513.8 8.4 2.4 255.4 75.5 12.0 9.3 430.3 455.6 3543.0 6959.4 49.9 5.6 494.0 474.4 3.2 1806.7 0.3 21.7 2.1 465.6 425.3 516.5 42.6 44.2 5.9 8.4 58.4 1096.4 76.3 431.0 3.9 1262.3 4.0 466.6 0.9 2886.6 0.9 2.6 14.2 25.8 430.1 0.4 0.0 0.0 0.0 0.0 0.0 4.4 8.6 1.7 1.1 0.4 0.0 0.0 0.1 16.2 0.0 0.1 1.8 0.2 1.2 0.9 0.8 0.0 4.3 0.0 3.5 4.5 1.0 0.6 1.7 0.0 11.4 0.0 0.1 0.0 0.0 0.3 1.2 0.7 0.0 3.7 251.3 0.5 0.0 0.0 0.0 0.8 70.8 40.8 0.0 21.8 3.0 0.5 1.3 1.1 10.8 0.0 107.8 0.0 0.0 0.8 1.7 0.3 0.6 1.9 0.6 2.0 1103.8 0.0 0.2 0.3 0.1 0.3 0.3 0.3 0.0 0.4 0.6 0.3 0.0 0.4 0.7 0.0 0.0 0.1 0.1 0.7 0.5 434.9 515.9 469.3 912.6 430.3 455.6 494.0 474.4 465.6 431.0 466.6 430.1 10.6 28.9 8.7 38.5 338.7 57.9 26.0 4.5 46.1 0.0 87.0 116.2 11.7 330.3 9.1 2302.6 0.0 3.9 9.8 3657.8 6849.7 74.4 0.3 2960.7 777.1 49.2 246.7 878.6 0.1 283.4 403.2 50.7 443.9 8167.8 17.2 16.8 310.2 16307.3 26.3 0.0 0.1 3688.0 0.0 379.5 4.9 0.9 23.3 765.6 30.2 2.8 10.6 0.0 2.1 2.0 0.1 339.8 10431.2 2.2 26.3 823.7 8631.3 77919.3 3.9 0.0 0.0 25.1 42.9 0.3 0.8 42.2 77.9 132.7 247.5 4.7 3786.7 21.1 MT1M "MT1, MT1K" ENSG00000205364 "Metallothionein 1M" Q8N339 16 56632659-56633981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 398.9;liver: 562.4" "Cell type enhanced" "Detected in many" "Adipocytes: 1333.5;Distal enterocytes: 906.4;Glandular and luminal cells: 1180.5;Hepatocytes: 1549.5;Paneth cells: 1204.8;Proximal enterocytes: 933.2;Smooth muscle cells: 680.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RPTEC TERT1: 181.8" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.83e-2)" "unprognostic (2.49e-1)" "unprognostic (2.10e-2)" "unprognostic (3.10e-2)" "unprognostic (4.19e-3)" "unprognostic (7.73e-2)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.13e-4)" "unprognostic (4.67e-2)" "unprognostic (3.10e-1)" "unprognostic (3.55e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-2)" "unprognostic (4.71e-2)" 398.9 27.7 214.3 32.8 233.5 0.1 145.6 240.4 316.0 31.2 183.0 134.0 21.2 14.8 4.1 83.4 95.4 42.6 36.6 207.3 219.5 47.6 562.4 116.5 4.5 225.3 226.8 16.1 145.8 2.6 10.4 2.7 232.6 57.5 140.9 24.7 31.5 6.7 48.2 44.6 113.6 37.3 217.6 7.7 98.5 3.9 246.4 5.2 64.3 4.0 2.5 33.4 26.1 213.6 0.0 0.0 0.0 0.0 39.1 27.3 0.5 1.2 9.9 1.2 2.4 0.4 0.6 0.0 7.9 6.3 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.2 0.1 3.1 0.0 14.8 0.0 23.7 0.0 0.0 0.0 0.0 19.6 0.0 0.1 0.2 13.4 0.0 1.3 0.0 0.1 0.2 181.8 0.0 0.2 0.5 0.0 0.0 0.0 1.7 0.0 2.7 5.5 0.1 0.0 1.8 0.0 0.1 0.0 0.2 4.7 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 214.3 233.5 240.4 316.0 207.3 219.5 225.3 226.8 232.6 217.6 246.4 213.6 1333.5 12.8 7.2 49.6 9.3 27.5 19.0 3.1 27.9 0.0 13.7 52.7 7.9 121.5 6.0 14.7 0.0 0.3 4.9 906.4 37.2 58.9 0.1 413.6 114.7 141.3 32.7 131.0 0.1 117.0 70.5 308.1 25.5 1180.5 15.9 11.9 82.8 1549.5 1.7 0.0 0.1 397.5 0.0 65.9 39.9 1.5 47.8 35.2 88.9 5.6 24.3 0.0 0.0 6.0 0.3 64.1 1204.8 12.0 29.4 152.4 933.2 258.6 5.2 0.0 78.9 587.1 680.1 0.0 0.5 4.7 20.2 1.0 15.5 1.2 559.6 7.9 MTARC1 "FLJ22390, MARC1, MOSC1" ENSG00000186205 "Mitochondrial amidoxime reducing component 1" Q5VT66 1 220786913-220819659 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 192.3;breast: 86.2;liver: 84.5" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 109.8;Extravillous trophoblasts: 47.9;Syncytiotrophoblasts: 75.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 30.2;classical monocyte: 33.6;eosinophil: 12.3;neutrophil: 42.8" "Group enriched" "Detected in many" 31 "granulocytes: 42.8;monocytes: 33.6" "Cell line enhanced" "Detected in many" "BEWO: 126.5;HeLa: 56.2;Hep G2: 67.6;NTERA-2: 57.8;OE19: 49.4" HPA028702 Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA028702: AB_10601135" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (2.16e-2)" "unprognostic (5.04e-2)" "unprognostic (2.90e-1)" "unprognostic (2.31e-1)" "unprognostic (3.71e-3)" "unprognostic (1.39e-1)" "unprognostic (7.51e-2)" "unprognostic (7.71e-3)" "unprognostic (3.71e-1)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.85e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" "unprognostic (1.50e-1)" 192.3 7.4 9.4 6.8 10.5 17.9 86.2 9.8 13.2 7.9 7.9 18.9 7.6 2.8 14.0 7.6 6.2 4.1 8.4 10.0 11.7 10.2 84.5 9.3 2.8 10.1 11.8 5.5 9.6 5.4 7.0 16.0 9.6 36.2 17.3 5.7 27.2 13.5 11.0 3.6 9.7 4.0 9.1 10.2 9.3 1.4 14.3 1.6 53.5 9.2 2.1 8.8 5.0 8.5 15.0 7.8 5.9 0.2 1.3 0.3 126.5 1.4 1.2 0.8 1.5 45.4 1.0 0.1 5.3 1.6 0.1 0.1 28.3 2.9 2.1 0.2 25.7 0.1 56.2 67.6 2.7 0.3 0.5 4.5 1.3 0.2 0.0 0.2 1.1 0.1 4.3 0.3 1.1 14.7 0.1 31.9 57.8 49.4 23.8 0.1 0.0 0.3 7.1 17.4 16.4 36.1 8.1 11.4 0.2 16.4 38.5 34.7 0.4 0.1 12.6 0.1 0.1 0.2 0.1 0.1 0.2 0.0 1.1 30.2 33.6 12.3 0.1 2.5 0.0 0.4 0.0 0.0 1.2 0.2 0.1 0.0 42.8 0.0 1.3 0.3 0.0 9.2 9.4 10.5 9.8 13.2 10.0 11.7 10.1 11.8 9.6 9.1 14.3 8.5 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 109.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 47.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 MTDH "3D3, AEG-1, LYRIC" ENSG00000147649 Metadherin Q86UE4 8 97644184-97730260 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010932, HPA015104, CAB068204, CAB068205" Supported Enhanced "Endoplasmic reticulum" NA NA 300000 "Cluster 26: Non-specific - Mitochondria" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB068204: AB_2665655, CAB068205: AB_2665654, HPA010932: AB_1079422, HPA015104: AB_1854173" "unprognostic (1.01e-3)" "unprognostic (1.41e-2)" "unprognostic (2.05e-2)" "unprognostic (6.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.24e-2)" "unprognostic (4.08e-2)" "prognostic unfavorable (7.76e-4)" "unprognostic (1.25e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.82e-4)" "unprognostic (3.84e-3)" "unprognostic (3.88e-2)" "unprognostic (2.77e-1)" "unprognostic (1.40e-1)" 53.3 41.4 18.6 56.0 26.7 109.9 39.0 26.2 24.5 52.6 27.2 51.3 51.2 50.1 33.7 52.2 41.1 41.2 35.7 17.2 21.2 40.8 89.6 40.7 59.3 28.3 23.2 50.7 30.4 53.4 13.4 28.9 28.6 44.7 47.5 44.8 29.3 41.4 60.2 27.0 52.2 62.5 25.9 41.6 48.1 39.6 23.3 65.9 62.7 50.6 61.0 56.3 22.7 37.1 191.5 96.4 61.1 84.7 97.3 102.7 30.7 167.8 139.0 104.2 79.4 59.9 137.0 173.5 181.5 164.6 114.1 121.6 150.3 115.2 143.6 189.5 79.9 320.0 97.5 69.6 118.2 170.5 142.4 78.6 109.3 128.1 282.2 97.3 119.3 126.2 215.5 300.2 108.4 77.6 286.0 43.2 38.9 160.9 113.0 187.2 73.0 255.4 64.5 108.6 92.3 69.2 118.3 101.3 132.0 58.6 158.0 105.1 126.8 146.7 52.7 135.8 123.6 166.1 196.4 174.5 134.3 194.5 130.9 57.0 71.5 38.1 35.7 49.2 49.7 71.6 51.1 52.8 87.0 51.4 51.9 45.7 10.1 51.4 54.6 112.2 33.3 31.9 18.6 26.7 26.2 24.5 17.2 21.2 28.3 23.2 28.6 25.9 23.3 37.1 185.1 128.2 109.2 69.2 294.6 261.7 233.0 178.9 194.1 0.0 166.1 150.7 109.9 201.6 146.1 141.6 0.0 10.0 231.7 140.5 25.4 230.9 267.4 156.0 269.9 185.1 121.8 205.7 96.4 231.7 98.6 227.2 156.5 178.5 137.1 183.1 164.6 438.0 267.5 0.0 97.0 249.9 146.5 258.7 273.9 163.5 195.4 266.5 184.9 86.2 258.2 0.0 195.7 110.6 141.8 241.8 137.8 216.3 675.9 374.7 160.8 99.2 87.2 0.0 223.5 237.8 334.5 162.1 129.6 249.8 314.8 13.7 200.3 285.6 251.6 315.0 MTFP1 "HSPC242, MTP18" ENSG00000242114 "Mitochondrial fission process 1" Q9UDX5 22 30425623-30429054 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 69.7;Exocrine glandular cells: 52.2;Plasma cells: 43.5;Undifferentiated cells: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077396 Approved Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA077396: AB_2686837" "unprognostic (2.19e-2)" "unprognostic (1.18e-1)" "unprognostic (3.12e-1)" "unprognostic (6.20e-2)" "unprognostic (4.86e-2)" "unprognostic (1.72e-3)" "unprognostic (1.52e-3)" "unprognostic (8.98e-2)" "unprognostic (2.07e-1)" "unprognostic (1.65e-1)" "unprognostic (6.37e-3)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (6.40e-2)" "unprognostic (3.06e-2)" "unprognostic (3.84e-1)" "unprognostic (1.66e-2)" 12.9 15.6 8.7 10.1 9.1 14.2 11.6 11.1 9.9 8.3 16.8 17.1 16.8 3.8 15.1 19.8 3.4 8.1 26.2 9.0 10.2 38.9 31.9 11.9 16.5 9.9 9.7 5.0 19.0 21.8 8.1 11.4 9.3 13.5 12.9 23.4 10.1 4.9 26.2 7.6 13.4 4.7 9.1 20.9 19.7 4.0 10.8 7.8 8.5 19.3 14.8 13.7 7.6 8.6 91.9 69.5 23.8 37.1 5.1 4.1 27.2 8.6 8.2 51.3 78.5 33.6 52.4 99.5 25.3 6.0 41.3 46.5 74.0 77.6 34.7 56.2 96.5 26.7 38.6 64.9 14.8 66.7 52.7 7.6 25.7 31.4 47.4 15.7 43.5 45.1 51.2 35.5 16.3 109.5 63.3 71.8 41.5 82.9 73.2 85.6 23.1 87.3 61.0 24.8 40.6 44.5 19.9 90.6 35.6 16.9 28.8 31.4 18.4 55.9 72.4 27.6 26.3 17.8 15.5 86.1 22.4 75.9 23.7 0.2 14.3 0.1 49.2 17.1 65.5 34.0 39.6 42.3 20.3 23.7 41.7 48.2 1.8 14.0 11.6 10.5 36.0 25.6 8.7 9.1 11.1 9.9 9.0 10.2 9.9 9.7 9.3 9.1 10.8 8.6 5.3 6.4 3.0 3.9 21.7 5.6 1.8 12.0 6.2 0.0 10.1 3.7 4.4 7.2 6.7 3.7 0.0 13.4 14.8 33.2 15.6 69.7 0.1 1.9 1.4 5.8 8.4 9.2 0.8 52.2 30.4 2.5 20.9 2.6 9.5 0.4 5.0 11.1 17.6 0.0 2.7 28.1 2.0 10.3 9.6 0.2 0.6 6.4 3.6 1.0 36.6 0.0 10.3 0.5 0.3 40.3 13.8 0.4 43.5 3.5 28.3 11.8 1.9 0.0 0.0 1.5 5.1 0.6 2.1 16.5 5.5 16.8 29.6 0.7 45.3 2.2 MTHFD2 ENSG00000065911 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" P13995 2 74186172-74217565 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 243.6;monocytes: 184.1;Smooth muscle cells: 239.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003684, HPA049657" Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "CAB003684: AB_425867, HPA049657: AB_2680842" "unprognostic (1.82e-3)" "unprognostic (4.60e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (2.07e-5)" "prognostic favorable (1.01e-4)" "unprognostic (3.10e-3)" "unprognostic (2.24e-3)" "unprognostic (4.75e-3)" "unprognostic (2.64e-2)" "unprognostic (3.96e-2)" "unprognostic (3.76e-3)" "unprognostic (3.57e-3)" "prognostic unfavorable (1.11e-16)" "unprognostic (3.66e-2)" "unprognostic (6.52e-2)" "unprognostic (9.07e-2)" "unprognostic (2.34e-3)" 40.0 12.3 11.2 54.5 13.0 25.8 34.8 12.7 14.7 28.5 11.2 30.6 18.6 21.5 14.5 23.0 34.2 20.1 19.6 10.0 16.6 19.6 7.3 23.0 45.6 16.6 15.8 11.7 65.9 9.8 18.0 17.7 17.1 16.3 33.7 2.9 17.7 16.7 36.7 11.8 16.0 27.3 14.8 19.0 36.1 17.7 13.1 28.5 18.5 55.3 57.8 48.0 20.5 15.7 197.4 107.8 89.2 235.6 90.0 113.9 186.1 286.2 185.2 156.2 216.7 242.8 81.8 391.0 65.4 154.2 167.5 70.7 296.7 142.0 314.9 248.9 100.9 424.6 55.4 181.9 319.8 360.1 234.8 202.9 423.4 188.5 794.4 74.8 99.0 636.5 192.2 548.0 157.5 159.6 209.5 261.0 161.1 293.3 95.8 222.6 266.3 339.4 72.0 80.8 198.2 143.8 97.4 238.3 549.7 56.9 208.5 324.4 52.9 39.1 359.9 97.7 286.5 484.5 257.6 379.2 111.4 304.1 132.5 43.9 24.0 31.1 8.5 56.6 13.0 13.4 15.2 10.1 34.9 12.2 11.5 7.9 3.2 29.3 57.0 13.0 36.8 22.0 11.2 13.0 12.7 14.7 10.0 16.6 16.6 15.8 17.1 14.8 13.1 15.7 19.7 16.0 20.2 0.3 49.7 89.3 58.8 54.1 27.3 0.0 53.2 38.0 11.5 4.3 28.2 1.8 0.0 31.5 48.2 19.9 3.9 55.7 3.9 9.7 104.7 35.1 19.1 104.1 1.0 107.9 56.9 45.6 68.8 21.7 53.3 8.7 19.2 0.8 66.2 0.0 3.7 64.0 38.7 61.6 243.6 3.8 22.7 100.6 71.2 12.2 184.1 0.0 27.8 6.6 1.1 81.2 7.5 21.1 141.2 95.7 3.3 3.3 8.5 0.0 138.1 126.3 239.0 36.5 54.9 42.0 74.6 14.0 71.4 21.6 34.0 64.2 MTMR14 "C3orf29, FLJ22405, FLJ90311, hEDTP, hJumpy" ENSG00000163719 "Myotubularin related protein 14" Q8NCE2 3 9649433-9702393 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054063 Approved "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "HPA054063: AB_2682365" "unprognostic (9.50e-2)" "unprognostic (5.60e-3)" "unprognostic (9.28e-2)" "unprognostic (1.31e-1)" "unprognostic (8.81e-3)" "unprognostic (2.34e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (2.42e-1)" "unprognostic (2.00e-1)" "unprognostic (3.51e-3)" "unprognostic (7.04e-2)" "unprognostic (1.37e-1)" "prognostic favorable (2.74e-4)" "unprognostic (1.25e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-1)" "unprognostic (1.01e-3)" 18.3 18.0 15.7 22.1 16.4 56.0 15.5 15.6 15.7 12.4 28.1 18.5 17.7 12.7 11.2 15.9 13.5 13.4 34.4 14.8 16.3 18.4 19.5 21.6 37.3 16.4 16.0 13.9 11.8 14.9 10.2 20.1 16.8 12.1 18.4 9.2 13.9 10.7 45.3 19.8 17.9 13.4 15.9 27.8 16.5 16.9 16.6 24.4 15.3 35.6 41.6 18.3 12.7 18.8 18.9 29.1 19.1 11.1 25.6 17.1 106.4 15.0 28.6 29.3 33.6 22.1 27.7 38.2 16.0 24.2 37.8 11.3 23.4 34.2 24.7 34.5 32.5 40.0 24.4 31.9 45.6 35.3 70.6 31.9 22.9 36.9 38.4 19.9 33.2 28.6 25.0 34.0 20.5 60.4 26.1 28.9 31.3 28.2 23.8 27.0 23.1 41.1 26.4 32.6 10.2 28.7 16.7 21.6 29.3 26.0 28.9 57.3 26.0 13.7 21.5 24.9 21.5 37.0 63.3 49.6 31.0 44.0 18.2 116.9 139.9 107.1 44.7 148.1 44.5 76.5 43.3 45.5 177.8 63.4 39.6 40.6 87.7 58.0 145.1 97.2 55.5 113.7 15.7 16.4 15.6 15.7 14.8 16.3 16.4 16.0 16.8 15.9 16.6 18.8 19.3 16.0 6.4 21.5 41.7 10.8 12.2 22.6 8.0 0.0 13.2 12.1 23.8 18.6 14.8 9.2 0.0 47.6 34.2 22.0 29.4 38.3 13.8 10.4 10.5 20.0 12.5 24.8 12.2 28.2 39.0 13.0 27.0 19.6 19.7 15.0 26.4 16.7 67.7 0.0 10.3 14.6 22.4 65.3 28.3 12.8 13.1 55.8 12.4 28.1 68.4 0.0 22.6 9.5 19.9 41.9 25.9 13.2 25.0 15.2 33.2 37.3 10.1 0.0 6.6 15.2 14.0 39.0 40.0 14.7 18.0 64.7 27.0 40.5 16.8 12.7 MTOR "FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1" ENSG00000198793 "Mechanistic target of rapamycin kinase" P42345 1 11106535-11262551 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069425, HPA071227" Approved Approved Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "CAB069425: , HPA071227: AB_2686367" "unprognostic (3.18e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (2.45e-3)" "unprognostic (5.50e-2)" "unprognostic (2.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "unprognostic (8.24e-3)" "unprognostic (3.48e-2)" "unprognostic (1.88e-1)" "prognostic favorable (1.49e-5)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" "unprognostic (6.60e-2)" "unprognostic (7.55e-2)" 16.3 19.4 18.2 13.5 19.0 14.0 16.8 18.4 20.1 15.2 18.6 22.8 11.0 17.5 21.8 18.3 14.6 9.0 23.6 19.7 17.7 24.1 27.6 15.2 15.3 16.5 21.2 14.2 18.3 20.6 21.8 11.8 18.4 19.8 16.0 26.9 16.5 13.8 36.4 17.1 19.6 13.8 14.6 21.2 18.7 33.8 22.7 19.2 17.8 17.8 15.9 17.1 14.9 18.7 28.5 25.2 33.3 25.4 39.4 18.6 16.6 23.4 22.3 30.6 29.9 26.0 25.5 31.4 19.6 27.8 18.8 33.1 45.3 35.8 39.3 25.2 33.2 41.7 53.8 33.4 24.7 41.1 29.7 24.0 26.8 43.7 44.0 14.5 39.3 29.6 47.4 26.1 21.6 32.4 28.5 31.2 25.3 29.6 23.5 28.2 39.2 21.0 27.2 25.3 33.4 24.5 50.1 26.8 31.2 36.5 21.8 24.0 42.3 26.5 23.9 20.5 31.8 25.5 25.5 60.5 19.1 43.6 28.6 0.3 1.1 1.3 1.9 2.4 1.6 1.4 1.1 1.0 1.6 1.1 1.3 1.1 0.8 1.1 1.3 1.2 2.4 1.0 18.2 19.0 18.4 20.1 19.7 17.7 16.5 21.2 18.4 14.6 22.7 18.7 9.2 16.0 11.8 40.8 10.0 3.4 5.2 7.6 8.6 0.0 7.7 7.5 25.1 2.8 10.3 9.2 0.0 7.9 9.8 9.4 1.9 8.5 42.0 13.8 16.1 11.0 10.3 14.3 43.8 6.2 7.2 9.2 16.8 18.6 13.3 12.9 5.3 13.4 6.9 0.0 49.2 7.8 6.1 8.2 4.1 36.1 7.8 9.1 8.8 36.5 9.2 0.0 10.3 38.2 37.4 10.4 5.4 8.2 17.2 8.9 7.0 4.5 6.3 0.0 39.5 11.4 12.1 49.3 37.4 15.6 5.7 9.9 9.8 15.3 10.0 5.7 MTRNR2L1 ENSG00000256618 "MT-RNR2 like 1" P0CJ68 17 22523415-22524663 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 20164.8;choroid plexus: 8845.1" "Cell type enriched" "Detected in many" 11 "Cardiomyocytes: 16283.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4804.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 4804.8" "Cell line enhanced" "Detected in all" "HeLa: 3045.1;Hep G2: 1708.1" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.08e-1)" "unprognostic (4.41e-3)" "unprognostic (2.99e-2)" "unprognostic (9.82e-3)" "prognostic favorable (8.99e-4)" "unprognostic (2.14e-1)" "unprognostic (2.59e-2)" "unprognostic (1.48e-2)" "unprognostic (2.42e-2)" "unprognostic (1.63e-2)" "unprognostic (2.56e-2)" "unprognostic (3.35e-2)" "unprognostic (1.64e-1)" "unprognostic (1.49e-2)" "unprognostic (5.21e-3)" 713.0 996.4 8845.7 173.6 8845.9 274.4 262.3 8845.0 20164.8 111.8 8845.1 625.8 358.0 130.9 204.8 373.7 139.4 196.7 2311.0 9146.7 8845.4 1188.8 941.5 142.9 125.6 9179.3 8845.3 138.8 404.2 616.0 0.0 184.5 9002.4 233.2 536.5 633.2 441.1 281.0 3639.3 418.2 401.8 204.0 8865.7 216.5 445.2 369.7 8847.1 119.8 100.4 3327.7 193.1 177.0 0.0 8862.4 268.9 621.7 231.5 771.3 365.2 150.1 292.9 243.5 59.4 57.5 66.0 386.2 417.6 362.9 260.2 130.7 40.4 685.1 18.1 90.8 71.0 214.7 441.0 331.6 3045.1 1708.1 118.5 77.8 376.1 338.0 191.1 63.1 152.7 407.1 62.9 232.2 276.6 211.5 172.8 222.1 121.7 528.1 65.0 208.0 138.3 196.3 145.4 186.7 321.5 380.3 121.8 215.0 119.2 217.6 376.5 222.6 205.9 551.4 118.8 302.6 251.1 364.1 156.7 196.5 68.6 174.1 169.9 483.3 67.0 2097.9 721.0 1313.4 204.5 325.1 248.2 597.3 255.0 225.8 245.8 585.3 331.9 301.3 4804.8 301.1 339.6 428.7 248.4 677.0 8845.7 8845.9 8845.0 20164.8 9146.7 8845.4 9179.3 8845.3 9002.4 8865.7 8847.1 8862.4 16.2 131.4 117.3 0.0 16.2 84.4 1432.1 2.8 0.0 0.0 54.3 88.4 16283.9 5.7 145.5 77.3 0.0 0.8 3.0 4.0 111.6 0.6 6.6 23.4 4.5 460.8 1.8 0.0 0.0 0.7 0.7 591.3 0.0 56.4 166.5 128.9 4.2 11.9 0.8 0.0 0.0 6.5 0.0 7.2 56.2 17.8 15.5 71.6 62.2 0.0 1.3 0.0 0.0 0.0 0.1 0.3 2.7 4.1 0.5 261.1 1.0 1169.4 101.8 0.0 0.0 346.1 450.7 10.2 18.2 0.0 171.3 1.0 79.5 34.6 2.2 749.7 MTRNR2L10 ENSG00000256045 "MT-RNR2 like 10" P0CJ77 X 55181392-55182442 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "brain: 1196.7" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 9177.9" "Cancer enhanced" "Detected in single" "stomach cancer: 0.6" "Region enriched" "Detected in all" 37 "cerebral cortex: 1196.7" "Group enriched" "Detected in all" 5 "basophil: 171.3;eosinophil: 137.1;neutrophil: 395.3" "Lineage enriched" "Detected in all" 8 "granulocytes: 395.3" "Cell line enhanced" "Detected in many" "A549: 178.6;HeLa: 834.8;Hep G2: 578.6" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (4.42e-1)" "unprognostic (3.04e-2)" "unprognostic (1.15e-1)" "unprognostic (5.10e-4)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (1.71e-2)" "unprognostic (8.42e-2)" "unprognostic (1.58e-2)" "unprognostic (9.01e-2)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (3.01e-1)" "unprognostic (6.28e-2)" "unprognostic (2.97e-2)" "unprognostic (4.99e-2)" "unprognostic (3.97e-4)" 38.3 32.2 18.5 5.8 18.6 8.3 3.7 18.5 1196.7 0.7 18.5 38.9 11.3 12.0 38.4 23.1 17.0 10.6 161.2 32.3 18.5 121.9 79.5 3.4 2.6 28.7 18.6 14.9 23.8 5.1 0.0 6.6 22.3 8.3 66.1 2.4 27.7 3.5 127.9 12.7 10.5 24.6 20.3 8.4 10.7 22.5 18.6 1.0 5.7 15.0 21.2 4.4 0.0 18.9 10.5 178.6 2.4 49.1 4.5 2.2 12.8 16.1 0.8 0.9 0.5 12.1 25.7 24.2 3.4 1.1 2.1 36.6 0.1 1.2 0.5 7.0 36.4 12.3 834.8 578.6 1.1 4.1 6.5 6.2 2.7 0.3 2.0 42.0 0.7 18.4 21.8 13.7 1.9 67.9 3.8 28.8 1.1 0.9 14.0 9.2 9.9 11.3 4.0 111.5 2.5 10.2 4.7 4.3 18.1 23.2 14.4 21.1 25.7 18.0 3.8 6.2 1.6 4.4 3.1 2.0 11.2 5.3 4.0 171.3 50.3 137.1 9.5 25.1 11.4 38.2 14.8 12.7 21.7 36.5 19.1 22.3 395.3 22.8 24.5 26.2 16.2 63.8 18.5 18.6 18.5 1196.7 32.3 18.5 28.7 18.6 22.3 20.3 18.6 18.9 3.8 0.0 0.0 0.0 4.9 8.2 411.9 1.0 0.0 0.0 15.8 6.6 9177.9 2.8 0.6 42.3 0.0 0.3 1.3 0.0 84.1 0.0 0.3 11.5 6.5 296.2 0.0 0.0 0.0 0.0 0.3 289.5 0.0 16.0 0.0 4.0 1.8 6.2 0.6 0.0 0.0 0.0 2.0 5.5 23.2 1.1 0.6 75.9 16.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.5 222.0 0.0 611.6 0.6 0.0 0.0 995.2 385.1 0.6 0.9 0.0 9.1 0.3 70.1 4.3 0.0 449.2 MTRNR2L11 ENSG00000270188 "MT-RNR2 like 11" S4R3Y5 1 237943724-237945275 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 13 "brain: 4100.7" "Group enriched" "Detected in some" 15 "Cardiomyocytes: 1131.8;Proximal tubular cells: 286.7" "Not detected" "Not detected" "Region enriched" "Detected in all" 11 "cerebral cortex: 4100.7" "Group enriched" "Detected in all" 4 "basophil: 95.3;eosinophil: 74.4;neutrophil: 274.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 274.5" "Cell line enhanced" "Detected in many" "HeLa: 302.4;Hep G2: 155.2" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.07e-1)" "unprognostic (9.70e-2)" "unprognostic (4.49e-2)" "unprognostic (5.26e-2)" 76.7 74.6 270.2 11.8 270.2 16.9 12.1 270.2 4100.7 4.2 270.3 48.8 23.6 12.8 7.2 6.7 5.4 3.8 88.5 355.4 270.2 73.9 52.3 7.6 5.5 358.1 270.2 8.6 26.1 25.0 0.0 9.0 302.0 16.1 23.8 40.6 30.9 11.3 324.5 12.5 27.3 9.3 280.2 16.7 33.1 19.9 270.4 4.7 2.4 121.4 8.1 5.8 0.0 271.2 26.2 59.8 27.3 77.1 23.1 5.8 21.8 42.4 3.5 2.4 3.4 25.5 36.7 44.3 26.5 8.4 4.4 77.4 0.9 5.6 2.3 19.5 41.2 44.6 302.4 155.2 7.6 12.6 34.4 23.3 8.1 2.8 10.3 53.2 3.5 28.5 31.8 25.7 7.2 22.3 12.6 42.3 7.4 32.1 10.8 23.6 22.2 18.1 16.4 35.4 10.4 18.2 16.6 19.3 33.0 26.7 23.5 39.1 68.7 30.7 21.6 25.0 12.4 19.4 6.9 17.4 17.0 42.6 7.6 95.3 33.0 74.4 6.0 13.8 6.9 23.9 9.0 8.1 11.9 23.4 12.4 13.3 274.5 12.8 14.4 15.0 8.9 42.9 270.2 270.2 270.2 4100.7 355.4 270.2 358.1 270.2 302.0 280.2 270.4 271.2 0.2 0.0 0.0 0.0 1.2 4.0 26.3 0.3 0.0 0.0 0.8 0.1 1131.8 0.0 0.0 12.9 0.0 0.1 0.1 0.0 46.9 0.0 0.1 0.2 0.1 22.9 0.0 0.0 0.0 0.0 0.1 33.1 0.0 0.2 0.0 0.0 1.1 1.6 0.1 0.0 0.0 0.0 0.0 0.8 9.0 0.1 0.0 3.0 8.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.9 0.0 286.7 0.0 0.0 0.0 6.5 25.6 0.3 0.3 0.0 4.0 0.0 1.8 0.1 0.0 17.7 MTRNR2L12 ENSG00000269028 "MT-RNR2 like 12" P0DMP1 3 96617188-96618236 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 125442.5;choroid plexus: 60537.0" "Cell type enriched" "Detected in many" 11 "Cardiomyocytes: 34487.4" "Cancer enhanced" "Detected in all" "stomach cancer: 14.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 23357.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 23357.3" "Cell line enhanced" "Detected in all" "HeLa: 19226.4" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (3.79e-2)" "unprognostic (1.05e-1)" "unprognostic (1.88e-2)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (9.76e-3)" "unprognostic (1.69e-3)" "unprognostic (1.81e-2)" "unprognostic (7.77e-2)" "unprognostic (3.55e-2)" "unprognostic (2.08e-2)" "unprognostic (4.90e-2)" "unprognostic (9.59e-3)" "unprognostic (1.81e-2)" "unprognostic (2.61e-1)" "unprognostic (2.08e-1)" "unprognostic (1.85e-2)" 7057.6 9488.3 60539.4 1610.0 60538.6 2401.2 2897.2 60547.3 125442.5 1316.1 60537.0 7130.2 3200.8 1495.8 1887.7 3942.3 1591.4 2141.9 24682.6 62534.7 60541.4 11477.3 10961.9 1405.1 1111.1 63276.7 60541.2 1471.0 3698.8 5500.5 0.9 1862.5 61842.9 2592.6 5672.7 5513.6 4076.4 3320.1 36694.8 4024.2 3630.6 2282.8 60728.7 1990.0 5139.8 3848.1 60548.8 1093.2 1305.3 22600.1 1986.4 1741.0 0.7 60592.0 3129.7 3743.3 2766.3 9914.1 4165.4 2220.4 2507.6 3970.8 808.2 749.3 954.5 2070.2 4888.5 6887.0 3132.2 1502.3 436.5 8365.9 196.7 1668.9 1010.6 2008.1 3570.2 7299.3 19226.4 8838.4 1579.3 1469.9 3824.2 4061.3 1945.5 784.9 2127.7 4578.8 844.6 3040.7 5258.3 2276.0 2553.9 1634.8 1252.5 4510.6 808.3 1892.5 1113.4 1992.1 2667.8 2102.8 4420.6 2269.6 1246.8 2408.9 2618.4 2595.6 3524.2 2439.6 2667.3 4152.9 3817.7 3062.1 2505.1 3462.1 1143.3 1197.9 802.7 3365.5 1896.5 8908.3 850.3 10533.0 3473.8 6467.2 1043.1 1696.3 1353.8 2636.4 1309.8 1129.5 1256.2 2611.9 1648.9 1580.6 23357.3 1490.6 1781.5 2078.4 1275.7 2740.2 60539.4 60538.6 60547.3 125442.5 62534.7 60541.4 63276.7 60541.2 61842.9 60728.7 60548.8 60592.0 1081.2 2705.1 2934.5 0.0 291.8 112.5 420.7 10.3 3.4 0.0 702.7 1431.3 34487.4 147.3 1441.4 84.6 0.0 8.4 394.0 24.5 62.6 1.1 19.7 1096.7 707.4 1236.7 4.9 182.7 0.0 1.8 8.6 1698.5 29.6 1465.4 1715.6 334.8 100.3 171.7 12.3 0.0 0.0 7.1 4.1 126.9 333.5 49.0 42.9 633.1 193.9 0.0 29.8 0.0 28.8 0.0 0.0 1.4 8.4 23.0 213.1 337.3 6.6 521.0 1431.8 0.0 46.0 2907.6 1520.5 36.3 39.6 3.3 80.7 10.5 625.8 220.9 5.2 397.1 MTRNR2L13 ENSG00000270394 "MT-RNR2 like 13" S4R3P1 4 116298876-116300320 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.0;choroid plexus: 1.7;skeletal muscle: 1.5" "Cell type enriched" "Detected in some" 20 "Cardiomyocytes: 176.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.5" "Group enriched" "Detected in some" 6 "HeLa: 4.3;Hep G2: 1.8" "Secreted - unknown location" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (6.40e-2)" "unprognostic (2.88e-1)" "unprognostic (2.49e-1)" "unprognostic (1.99e-1)" 0.2 0.6 1.8 0.0 1.8 0.1 0.0 1.8 3.0 0.0 1.7 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.9 1.9 1.8 0.6 0.3 0.1 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 1.8 0.0 0.2 0.0 0.1 0.0 1.5 0.1 0.2 0.0 1.8 0.0 0.1 0.1 1.8 0.0 0.0 1.0 0.0 0.0 0.0 1.8 0.1 0.4 0.0 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 4.3 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.1 1.8 1.8 1.8 3.0 1.9 1.8 1.8 1.8 1.8 1.8 1.8 1.8 0.0 0.0 0.0 0.0 0.0 0.1 8.4 0.0 0.0 0.0 0.0 0.0 176.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 3.8 0.0 0.0 0.0 0.8 4.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.7 MTRNR2L3 ENSG00000256222 "MT-RNR2 like 3" P0CJ70 20 57358447-57359498 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.0;skeletal muscle: 1.0" "Cell type enriched" "Detected in some" 49 "Cardiomyocytes: 3203.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebral cortex: 3.0" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cell line enhanced" "Detected in single" "HeLa: 1.1" "Secreted - unknown location" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 47: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.55e-4)" "unprognostic (2.65e-1)" "unprognostic (2.59e-1)" "unprognostic (8.34e-2)" "unprognostic (2.64e-1)" "unprognostic (1.80e-2)" "unprognostic (9.44e-6)" "unprognostic (2.56e-1)" "unprognostic (6.68e-2)" "unprognostic (5.35e-3)" "unprognostic (1.52e-3)" "unprognostic (7.52e-2)" "unprognostic (5.36e-2)" "unprognostic (4.37e-2)" "unprognostic (2.44e-1)" "unprognostic (1.18e-1)" "unprognostic (2.94e-3)" 0.0 0.1 0.2 0.0 0.3 0.2 0.0 0.5 3.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.3 0.2 0.2 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 1.1 0.0 0.1 0.0 0.1 0.1 0.2 0.3 0.5 3.0 0.4 0.3 0.3 0.3 0.4 0.2 0.3 0.5 0.7 0.0 0.0 0.0 1.0 3.2 32.3 0.3 0.0 0.0 2.4 1.3 3203.4 1.5 0.1 0.0 0.0 0.4 0.2 0.0 1.9 0.0 0.1 0.3 0.3 58.4 0.0 2.7 0.0 0.0 0.4 64.9 0.0 0.7 0.0 0.2 2.2 2.6 0.7 0.0 0.0 0.0 0.0 3.9 12.0 0.5 1.5 1.8 7.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 17.7 0.0 10.6 0.1 0.0 0.0 9.2 60.8 0.3 0.7 0.0 3.1 0.5 1.2 0.1 0.0 18.1 MTRNR2L4 ENSG00000232196 "MT-RNR2 like 4" P0CJ71 16 3370979-3372668 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 293.5" "Cell type enriched" "Detected in some" 14 "Cardiomyocytes: 154.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 168.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 168.2" "Cell line enhanced" "Detected in many" "AN3-CA: 48.8;HaCaT: 51.3;HeLa: 88.0" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (8.53e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-1)" "unprognostic (1.80e-1)" "unprognostic (1.05e-1)" "unprognostic (3.66e-3)" "unprognostic (1.58e-1)" "unprognostic (1.37e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-1)" "unprognostic (6.81e-3)" "unprognostic (1.65e-1)" "unprognostic (2.79e-1)" "unprognostic (1.19e-1)" "unprognostic (9.27e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" 18.0 52.7 25.5 10.8 25.5 9.4 2.4 27.1 54.2 1.1 25.6 14.7 20.7 4.7 2.2 10.8 2.3 3.4 66.0 28.2 25.6 31.8 17.1 5.7 3.8 27.7 25.5 4.8 13.8 1.7 0.3 6.4 26.8 7.3 9.1 7.3 17.0 2.8 293.5 9.7 21.7 3.4 25.7 9.1 19.1 12.2 25.7 0.2 1.8 3.2 3.3 1.4 0.1 26.9 13.8 8.8 2.6 48.8 1.1 1.6 15.0 7.3 0.4 0.9 0.7 4.2 28.7 10.2 14.5 0.4 0.3 51.3 0.1 0.5 0.4 7.8 5.0 9.0 88.0 36.6 0.2 3.0 23.5 1.0 0.7 0.2 0.5 1.1 0.1 1.1 6.9 13.6 1.5 3.0 6.4 23.8 4.0 0.5 1.7 11.6 6.9 9.2 2.1 10.2 5.7 13.0 4.6 11.6 19.1 0.8 16.1 22.7 6.6 15.4 13.5 18.0 5.3 7.1 2.5 9.7 10.6 22.8 3.7 62.3 25.6 72.1 4.9 12.9 5.5 14.3 6.2 6.4 11.1 16.5 6.9 8.7 168.2 8.6 13.4 13.4 7.7 23.3 25.5 25.5 27.1 54.2 28.2 25.6 27.7 25.5 26.8 25.7 25.7 26.9 0.2 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 154.2 2.8 0.0 1.8 0.0 0.1 0.1 0.0 3.9 0.0 0.0 0.1 0.2 3.1 0.0 0.0 0.1 0.2 0.0 3.3 0.0 0.2 0.0 0.1 0.4 0.2 0.1 0.0 0.0 0.5 0.0 0.6 0.7 0.0 0.0 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 1.8 0.0 10.4 0.0 0.0 0.0 2.5 3.3 1.0 0.3 0.0 0.3 0.1 0.4 0.1 0.0 1.4 MTRNR2L5 ENSG00000249860 "MT-RNR2 like 5" P0CJ72 10 55599042-55600728 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 2.3" "Cell type enriched" "Detected in some" 18 "Cardiomyocytes: 27.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basophil: 1.2;neutrophil: 1.2" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.2" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.11e-2)" "unprognostic (1.20e-1)" 0.0 0.1 1.2 0.1 0.9 0.3 0.0 0.5 1.5 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 1.3 1.7 0.1 0.1 0.0 0.2 1.3 1.4 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.6 0.2 0.1 0.0 0.6 0.2 0.1 0.0 2.3 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 1.2 0.2 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 1.2 0.2 0.1 0.1 0.0 0.1 1.2 0.9 0.5 1.5 1.3 1.7 1.3 1.4 1.0 0.6 2.3 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 27.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 MTRNR2L7 ENSG00000256892 "MT-RNR2 like 7" P0CJ74 10 37601440-37602974 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "brain: 2.1" "Cell type enriched" "Detected in some" 26 "Cardiomyocytes: 188.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.28e-1)" "unprognostic (5.87e-2)" 0.0 0.1 0.4 0.0 0.5 0.1 0.0 0.4 2.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.1 0.1 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 2.1 0.4 0.5 0.5 0.4 0.5 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 188.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.6 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 MTRNR2L8 ENSG00000255823 "MT-RNR2 like 8" P0CJ75 11 10507894-10509186 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 20406.5;choroid plexus: 8122.9;skeletal muscle: 7550.7" "Cell type enriched" "Detected in many" 11 "Cardiomyocytes: 32407.2" "Cancer enhanced" "Detected in many" "stomach cancer: 6.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 3689.6;eosinophil: 2784.3;neutrophil: 9219.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 9219.1" "Cell line enhanced" "Detected in all" "HeLa: 3532.5;Hep G2: 1873.3" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (6.19e-2)" "unprognostic (1.43e-1)" "unprognostic (6.66e-2)" "unprognostic (3.26e-2)" "unprognostic (3.71e-2)" "unprognostic (3.52e-2)" "unprognostic (2.81e-2)" "unprognostic (3.45e-2)" "unprognostic (5.28e-2)" "unprognostic (1.41e-1)" "unprognostic (4.87e-2)" "unprognostic (1.90e-1)" "unprognostic (4.59e-2)" "unprognostic (4.59e-2)" "unprognostic (3.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.96e-2)" 1000.1 1776.9 8126.4 330.8 8126.2 480.5 249.4 8126.3 20406.5 105.8 8122.9 906.3 612.7 222.9 263.8 642.6 200.9 300.7 3864.2 8509.5 8134.6 1780.1 1280.5 190.2 198.6 8655.4 8131.2 239.2 613.2 509.7 1.3 236.5 8396.6 342.3 741.4 864.6 742.7 271.9 7550.7 621.6 723.9 285.9 8194.3 375.6 681.5 599.0 8130.7 96.8 149.4 1897.1 267.0 201.6 0.6 8143.9 527.3 715.6 334.3 1521.1 294.0 151.4 438.7 562.6 61.4 61.1 75.9 427.1 742.2 698.2 544.0 91.4 54.0 1407.6 10.0 103.2 66.3 307.0 613.3 685.6 3532.5 1873.3 109.4 143.3 625.4 277.5 137.1 58.0 141.0 578.3 54.0 412.8 543.6 353.2 180.7 260.8 202.2 910.4 124.0 222.2 194.5 333.0 287.7 352.4 328.7 447.0 186.5 418.8 248.4 399.0 703.2 282.9 418.6 836.4 416.2 433.8 414.5 508.2 189.6 213.6 116.4 414.1 313.4 1053.0 125.3 3689.6 1275.5 2784.3 319.4 577.0 409.2 944.6 407.8 353.4 445.8 957.8 509.9 480.1 9219.1 466.8 613.2 688.5 439.4 1155.3 8126.4 8126.2 8126.3 20406.5 8509.5 8134.6 8655.4 8131.2 8396.6 8194.3 8130.7 8143.9 649.6 830.1 866.0 0.0 131.5 471.7 1069.8 27.1 1.2 0.0 599.2 1010.1 32407.2 124.4 492.7 57.0 0.0 6.9 118.0 2.1 72.4 0.0 23.1 785.5 473.5 1034.0 0.0 139.8 0.0 0.0 6.9 1450.7 3.1 916.4 543.7 140.3 119.2 384.5 12.8 0.0 0.0 0.5 4.1 129.6 1091.1 52.7 65.6 420.6 723.9 0.0 14.5 0.0 8.2 0.0 0.3 0.1 0.3 44.8 92.0 618.5 0.3 770.4 481.4 0.0 65.7 2750.1 1533.4 30.9 38.2 0.8 488.9 11.2 370.6 42.0 0.5 1232.9 MTRR cblE ENSG00000124275 "5-methyltetrahydrofolate-homocysteine methyltransferase reductase" Q9UBK8 5 7851186-7906025 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.1;Late spermatids: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038113 Supported Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cytosol" "Intermediate filaments" "HPA038113: AB_10671520" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (5.32e-2)" "unprognostic (1.17e-2)" "unprognostic (1.63e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.60e-4)" "unprognostic (2.56e-2)" "unprognostic (5.82e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (9.11e-3)" "unprognostic (3.44e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" 11.2 10.6 5.1 9.5 11.2 5.7 6.3 10.1 10.9 7.2 3.4 8.3 8.9 11.7 12.3 9.3 9.6 11.8 14.4 6.5 9.0 18.7 19.4 13.1 11.1 10.9 10.4 11.4 11.9 12.8 6.7 10.8 10.6 9.0 10.1 19.2 10.5 7.1 28.9 9.1 10.2 12.0 8.2 6.7 6.7 7.1 9.3 7.5 9.0 32.9 10.6 14.4 5.5 20.0 19.3 18.1 10.2 20.0 34.0 13.6 25.1 31.1 18.5 16.5 15.4 27.8 15.1 32.6 27.9 24.6 27.4 11.8 17.0 14.2 27.9 22.9 15.8 14.6 62.0 15.3 21.9 23.4 6.8 18.3 11.4 24.6 18.4 20.4 10.4 8.0 21.9 24.2 9.8 4.2 14.2 11.7 7.3 29.4 19.0 12.4 9.5 14.1 16.2 16.0 14.0 2.5 51.6 33.7 28.6 18.1 10.7 17.5 14.6 31.9 19.7 24.1 22.7 34.7 13.5 27.3 23.1 50.5 19.1 5.3 4.0 3.0 4.1 5.5 7.0 3.3 6.5 5.7 3.6 3.3 4.1 3.6 0.1 3.1 4.4 2.3 9.1 3.3 5.1 11.2 10.1 10.9 6.5 9.0 10.9 10.4 10.6 8.2 9.3 20.0 7.7 16.0 70.1 10.1 11.1 16.3 9.4 4.6 12.0 0.0 9.7 5.1 12.9 5.7 9.0 9.2 0.0 9.9 11.4 11.0 21.5 10.2 50.1 10.0 10.7 8.0 9.6 12.4 25.4 5.5 8.9 11.8 9.2 6.7 10.2 6.5 8.6 19.3 7.7 0.0 20.8 9.1 0.0 11.1 9.4 99.2 10.5 9.7 1.8 15.0 8.1 0.0 7.2 20.1 50.9 7.2 6.0 11.7 26.5 14.3 8.7 28.9 10.1 0.0 6.6 10.7 10.1 17.4 13.1 10.5 20.6 11.2 13.8 11.8 9.4 8.7 MTTP "ABL, MTP" ENSG00000138823 "Microsomal triglyceride transfer protein" P55157 4 99564081-99623997 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 275.2;liver: 266.6" "Group enriched" "Detected in many" 9 "Hepatocytes: 244.2;Proximal enterocytes: 605.4" "Cancer enriched" "Detected in many" 13 "liver cancer: 28.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 10.8;Hep G2: 12.2" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA051170, HPA054862" Uncertain Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 640000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum, Cytosol" "HPA051170: , HPA054862: AB_2682628" "unprognostic (1.66e-2)" "unprognostic (1.14e-1)" "unprognostic (5.64e-2)" "unprognostic (5.33e-2)" "unprognostic (3.49e-3)" "unprognostic (7.38e-2)" "unprognostic (1.05e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (3.66e-2)" "unprognostic (1.00e-2)" "unprognostic (1.62e-1)" "unprognostic (1.27e-3)" "unprognostic (2.02e-2)" "unprognostic (3.64e-1)" "unprognostic (1.53e-2)" "unprognostic (1.31e-1)" 0.3 0.1 0.9 0.2 0.9 0.0 0.2 0.8 0.9 0.1 0.3 1.3 243.2 0.1 1.0 0.1 0.6 1.3 0.9 0.8 1.5 12.9 266.6 0.3 0.3 1.1 1.6 2.0 0.0 0.0 0.5 0.0 1.3 0.5 0.3 5.6 0.1 0.2 0.4 0.1 275.2 0.5 1.2 0.0 0.8 9.6 1.2 0.2 0.1 0.3 0.1 0.9 0.0 1.9 0.0 0.2 10.8 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.2 0.1 12.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.6 0.5 0.1 0.2 0.1 0.1 1.0 0.0 0.0 0.7 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.8 0.9 0.8 1.5 1.1 1.6 1.3 1.2 1.2 1.9 0.1 0.0 0.0 4.6 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.8 4.3 0.1 1.8 0.0 0.2 0.2 0.2 0.0 0.0 44.2 1.0 0.1 0.1 0.0 2.7 1.6 0.0 0.0 0.8 1.5 0.2 0.0 30.1 3.6 244.2 0.1 0.0 0.7 16.7 2.0 3.5 0.0 12.0 0.9 0.2 0.0 0.0 0.6 0.0 0.0 0.0 2.0 0.2 12.5 0.4 0.1 0.0 605.4 23.5 1.0 0.0 6.6 0.5 0.5 32.1 5.7 0.0 0.0 0.0 0.4 12.0 21.0 0.0 MTURN "C7orf41, Ells1, FLJ25903" ENSG00000180354 "Maturin, neural progenitor differentiation regulator homolog" Q8N3F0 7 30134986-30162762 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 14 "brain: 1933.2;choroid plexus: 740.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 156.5" "Cancer enhanced" "Detected in all" "glioma: 29.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 8.2;NK-cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 52.9;HEL: 96.2;SCLC-21H: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029507 Enhanced Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA029507: AB_10601149" "unprognostic (1.99e-1)" "unprognostic (1.38e-2)" "unprognostic (3.70e-1)" "unprognostic (7.14e-2)" "unprognostic (1.84e-1)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (1.89e-3)" "unprognostic (9.80e-2)" "unprognostic (1.94e-1)" "unprognostic (1.11e-3)" "unprognostic (8.11e-3)" "prognostic favorable (7.64e-13)" "unprognostic (9.50e-2)" "unprognostic (7.64e-2)" "unprognostic (4.64e-1)" "unprognostic (3.26e-1)" 88.4 10.8 1190.3 9.7 1373.7 23.3 41.6 1103.3 1933.2 25.7 740.3 35.8 5.4 19.4 95.3 19.5 21.1 10.4 25.0 946.3 1044.1 50.3 4.1 20.9 5.4 1359.2 1275.8 33.4 12.9 15.7 17.4 7.5 1312.7 19.2 10.0 41.0 35.2 23.8 36.6 23.2 13.8 17.0 1311.0 8.3 26.4 10.9 1260.6 7.5 14.7 59.8 5.4 32.1 20.0 1483.6 12.5 2.1 7.1 7.6 52.9 35.9 6.4 6.0 7.0 2.0 2.8 1.0 5.0 0.7 4.8 13.3 11.0 2.4 16.4 23.6 6.4 5.4 13.2 96.2 16.1 6.7 4.1 4.8 30.8 17.9 10.8 6.2 10.9 8.6 3.2 13.1 6.4 5.0 13.8 4.8 5.6 2.3 4.9 11.6 7.5 0.5 16.3 21.4 24.1 5.1 68.7 18.2 3.8 19.1 19.4 6.6 13.5 7.1 15.5 7.8 8.5 16.6 8.5 8.3 12.7 1.1 10.4 10.3 4.0 8.2 0.3 3.6 0.3 0.2 0.1 0.5 0.2 0.1 0.4 0.3 0.1 0.3 2.2 2.1 0.0 1.0 0.7 1.4 1190.3 1373.7 1103.3 1933.2 946.3 1044.1 1359.2 1275.8 1312.7 1311.0 1260.6 1483.6 38.9 16.0 20.0 18.6 5.6 37.5 17.8 6.6 13.1 0.0 48.3 40.8 27.6 17.2 10.2 44.1 0.0 2.6 32.1 3.2 156.5 8.3 14.1 46.6 16.9 18.9 54.1 35.1 55.9 8.6 7.3 24.6 7.7 52.6 6.3 16.6 26.0 5.0 5.3 0.0 34.7 9.1 0.0 23.4 16.8 32.5 17.1 29.3 55.2 37.5 12.1 0.0 6.2 16.6 77.1 10.4 5.9 12.4 4.9 26.6 0.4 11.2 26.6 0.0 6.6 17.8 30.2 2.0 7.3 11.4 36.8 2.2 7.4 5.9 6.0 23.0 MTX2 ENSG00000128654 "Metaxin 2" O75431 2 176269395-176338025 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 201.5;Spermatocytes: 247.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031550, HPA031551, HPA031552" Approved Approved Supported Nucleoli,Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria Nucleoli "HPA031550: AB_10599733, HPA031551: AB_10601442, HPA031552: AB_10794616" "unprognostic (2.61e-1)" "unprognostic (9.86e-2)" "unprognostic (6.54e-2)" "prognostic unfavorable (5.06e-4)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "unprognostic (2.87e-2)" "unprognostic (3.97e-2)" "unprognostic (1.80e-2)" "unprognostic (8.30e-2)" "unprognostic (1.22e-1)" "unprognostic (2.03e-1)" "unprognostic (9.92e-2)" "unprognostic (3.15e-2)" "unprognostic (1.33e-2)" 20.4 37.4 31.8 15.2 33.6 9.2 27.0 32.8 46.7 22.1 35.9 31.2 22.8 18.7 39.3 38.1 28.9 14.5 49.8 33.3 34.4 46.4 30.8 15.6 14.2 33.9 32.0 21.1 26.3 48.1 29.5 25.8 33.2 26.4 35.5 47.3 20.4 22.6 74.4 23.4 20.2 25.7 34.0 15.6 24.4 64.3 33.5 18.2 20.4 70.9 20.8 25.1 24.7 35.6 52.2 31.0 60.8 37.8 40.0 45.9 58.3 54.5 52.0 49.8 58.3 53.1 55.8 66.4 91.4 49.1 79.9 34.5 67.1 67.6 67.9 66.6 49.4 63.9 39.1 94.9 62.7 98.9 20.7 51.1 83.5 52.2 89.1 60.3 72.0 64.3 86.8 50.2 59.6 47.4 34.9 102.9 58.3 101.8 45.5 0.0 44.0 60.8 142.4 93.3 87.0 74.4 45.7 60.9 120.7 116.4 33.7 64.0 63.5 49.2 43.5 52.1 57.9 55.4 62.1 79.8 61.1 49.7 60.8 8.0 9.3 4.1 9.6 15.8 13.1 18.9 12.4 11.1 14.8 13.7 14.9 15.4 0.0 19.6 14.4 12.1 16.9 9.9 31.8 33.6 32.8 46.7 33.3 34.4 33.9 32.0 33.2 34.0 33.5 35.6 34.4 19.2 22.6 50.6 20.8 31.1 36.2 130.9 37.5 0.0 38.2 43.8 69.2 31.5 63.6 57.0 0.0 78.8 11.1 38.8 201.5 51.8 22.3 60.9 25.7 31.4 41.5 19.5 106.0 39.5 63.3 30.2 28.1 33.9 43.1 25.7 16.4 33.7 47.8 0.0 106.3 47.7 103.7 21.7 15.7 18.8 35.4 19.6 35.6 43.1 26.1 0.0 12.3 93.5 180.2 49.8 26.1 32.7 23.1 48.2 39.6 106.3 63.8 0.0 39.5 24.9 52.4 247.8 127.1 56.5 41.9 65.0 18.8 55.8 52.6 53.7 MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1370.0;Collecting duct cells: 491.1;Exocrine glandular cells: 1164.9;Gastric mucus-secreting cells: 640.6;Pancreatic endocrine cells: 1074.8;Respiratory ciliated cells: 555.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Group enriched" "Detected in many" 6 "CAPAN-2: 1146.1;OE19: 548.3;RPTEC TERT1: 870.2;T-47d: 383.6" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" 15.2 6.3 5.3 21.9 5.7 9.4 78.2 4.7 8.6 194.2 4.7 176.0 21.4 40.2 61.6 209.9 120.0 125.8 6.8 5.1 5.7 485.8 3.9 321.5 1.8 7.8 6.3 9.8 358.5 1.0 14.1 3.3 6.0 43.9 103.6 1.3 135.0 34.4 1.9 20.6 35.2 20.0 6.1 5.4 1064.7 47.9 6.8 1.2 54.8 0.7 18.8 102.0 50.0 5.2 15.3 8.2 5.1 4.8 3.9 4.2 1.7 5.6 12.2 6.2 15.2 0.2 1146.1 0.0 81.9 9.5 2.7 23.2 1.0 0.3 1.8 10.4 0.8 1.8 101.5 0.0 2.4 0.4 36.1 9.5 2.1 2.8 2.2 12.7 2.1 1.9 9.2 15.4 4.3 120.0 1.6 1.2 3.5 548.3 2.1 2.3 0.6 29.3 870.2 0.9 5.1 2.1 28.0 48.3 1.5 4.1 383.6 5.6 2.2 3.9 6.7 10.5 1.2 17.7 9.8 0.2 5.9 1.1 1.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.1 5.3 5.7 4.7 8.6 5.1 5.7 7.8 6.3 6.0 6.1 6.8 5.2 2.3 432.7 1370.0 5.9 6.4 0.6 18.5 126.4 0.0 1.3 219.2 48.5 0.4 327.5 374.9 491.1 4.2 0.5 1.5 271.8 35.2 177.3 32.7 245.2 28.8 8.0 30.6 1.3 0.3 1164.9 1.1 7.0 640.6 282.8 48.0 0.3 1.8 0.9 0.2 1.7 0.3 351.5 164.8 2.2 1.0 81.0 2.5 7.2 5.4 1.0 24.3 1.7 0.0 0.5 0.1 1074.8 60.5 1.5 1.3 16.3 6.8 1.3 555.3 0.2 0.0 2.0 22.0 5.8 0.8 3.5 1.1 0.3 10.3 0.1 220.8 154.5 MUC13 DRCC1 ENSG00000173702 "Mucin 13, cell surface associated" Q9H3R2 3 124905442-124953819 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 614.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 853.2;Intestinal goblet cells: 418.5;Paneth cells: 641.9;Proximal enterocytes: 422.5;Undifferentiated cells: 207.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 198.4;stomach cancer: 152.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "OE19: 220.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045163, HPA079663" Enhanced "Secreted to digestive system" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA045163: AB_10960396, HPA079663: " "unprognostic (8.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (1.55e-3)" "unprognostic (2.93e-1)" "unprognostic (2.11e-2)" "unprognostic (1.26e-1)" "unprognostic (3.48e-2)" "unprognostic (2.94e-1)" "unprognostic (5.10e-2)" "unprognostic (2.02e-1)" "unprognostic (9.64e-2)" "prognostic unfavorable (9.73e-5)" "unprognostic (2.05e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "unprognostic (1.42e-1)" 0.8 0.8 0.0 62.0 0.0 0.1 0.5 0.0 0.1 0.8 0.0 304.6 614.6 1.5 0.0 0.8 2.8 47.9 0.1 0.0 0.0 17.5 3.7 0.3 0.4 0.2 0.0 0.0 4.5 0.0 0.1 0.0 0.3 2.1 301.3 0.0 0.0 0.8 0.0 0.1 503.8 10.9 0.0 0.1 35.3 0.3 0.0 0.0 0.0 0.1 0.1 0.8 0.1 0.0 0.0 7.4 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.1 6.4 13.6 0.0 0.8 0.2 0.1 1.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.9 0.1 0.0 0.0 1.0 0.0 220.9 1.1 0.0 0.1 2.7 0.0 0.0 0.3 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.1 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 3.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.3 25.8 0.8 0.0 0.0 0.0 0.0 853.2 0.0 24.7 0.9 120.0 1.5 0.4 153.8 0.0 0.1 31.4 0.0 0.0 36.7 6.1 8.9 0.0 0.0 0.0 0.0 0.0 0.2 418.5 0.0 0.3 0.0 4.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.8 641.9 0.7 0.0 1.5 422.5 7.7 10.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 1.5 0.0 207.9 1.4 MUC15 ENSG00000169550 "Mucin 15, cell surface associated" Q8N387 11 26559032-26572263 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "epididymis: 1949.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 109.0;Respiratory ciliated cells: 168.3;Syncytiotrophoblasts: 665.9" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 56.7" "Region enriched" "Detected in single" 7 "basal ganglia: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.9;K-562: 11.7;SK-BR-3: 18.0;SuSa: 12.0;U-266/70: 7.8;U-266/84: 21.1" "Group enriched" "Detected in some" 4 "cerebellum: 1.2;thalamus: 1.4" "Low region specificity" "Detected in many" "HPA026110, HPA073304" Enhanced "Intracellular and membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 16: U-266 - Nucleosome" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA026110: AB_1854200, HPA073304: " "unprognostic (1.49e-1)" "unprognostic (2.08e-3)" "unprognostic (7.71e-5)" "unprognostic (5.09e-3)" "unprognostic (2.77e-2)" "unprognostic (3.04e-2)" "unprognostic (6.58e-2)" "unprognostic (1.12e-1)" "unprognostic (9.44e-3)" "unprognostic (1.98e-1)" "unprognostic (7.27e-3)" "unprognostic (4.96e-3)" "unprognostic (1.09e-1)" "unprognostic (5.70e-2)" "unprognostic (4.54e-3)" 0.1 0.3 0.4 0.0 4.5 0.0 15.4 0.0 0.6 6.5 1.1 0.0 0.0 0.4 1949.7 17.4 6.7 0.1 0.0 0.3 0.0 24.1 0.1 12.3 0.1 0.0 0.0 0.0 7.8 0.0 1.4 14.8 0.1 0.9 0.0 0.0 52.2 6.8 0.0 29.4 0.0 0.0 0.0 0.0 1.0 0.2 0.0 3.6 75.7 0.0 7.7 2.5 11.6 0.1 0.6 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.7 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.2 0.6 0.0 18.0 0.0 12.0 0.2 0.0 0.0 0.0 3.1 0.0 0.0 7.8 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.5 0.0 0.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 109.0 32.5 0.0 0.1 3.4 12.5 7.5 4.6 0.0 43.0 6.9 0.0 0.0 55.1 49.7 0.0 68.7 0.0 0.0 31.3 4.6 0.6 39.8 5.4 0.7 0.0 0.0 0.2 0.0 19.2 1.3 0.0 53.1 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 8.2 0.0 0.6 0.2 0.0 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 168.3 0.0 0.0 0.0 2.2 0.2 0.2 26.5 29.7 665.9 0.4 0.0 0.0 12.6 MUC2 ENSG00000198788 "Mucin 2, oligomeric mucus/gel-forming" 11 1074875-1110511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 133.8" "Cell type enriched" "Detected in some" 12 "Intestinal goblet cells: 745.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 93.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB016275 Enhanced "Intracellular and membrane" NA NA "Cluster 27: Mucus-secreting cells - Mucin production" "CAB016275: AB_627970" "unprognostic (6.37e-2)" "unprognostic (8.32e-2)" "unprognostic (5.76e-3)" "unprognostic (5.09e-2)" "unprognostic (6.18e-3)" "unprognostic (3.39e-2)" "unprognostic (1.71e-2)" "unprognostic (5.76e-3)" "unprognostic (7.87e-2)" "unprognostic (2.04e-1)" "unprognostic (7.37e-3)" "unprognostic (4.20e-2)" "unprognostic (3.64e-5)" "unprognostic (1.38e-1)" "unprognostic (1.22e-1)" "unprognostic (3.10e-2)" 0.6 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.8 31.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.7 0.0 0.0 0.5 0.0 0.0 79.9 4.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 18.0 0.0 0.4 0.0 0.0 0.0 0.0 60.3 0.0 0.3 0.0 0.1 0.0 0.6 14.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 8.9 0.0 0.0 0.0 0.0 0.0 0.0 745.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 31.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 34.3 0.0 MUC20 "FLJ14408, KIAA1359" ENSG00000176945 "Mucin 20, cell surface associated" Q8N307 3 195720884-195741123 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 58.5;kidney: 69.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.2;Ductal cells: 55.5;Ionocytes: 152.5;Respiratory ciliated cells: 66.5;Urothelial cells: 84.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SK-BR-3: 28.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042249 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 170000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042249: " "unprognostic (1.85e-1)" "unprognostic (4.64e-2)" "unprognostic (1.05e-2)" "unprognostic (1.83e-3)" "unprognostic (2.12e-1)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (2.41e-1)" "unprognostic (3.99e-4)" "unprognostic (7.66e-2)" "unprognostic (2.84e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.57e-4)" "unprognostic (2.05e-1)" "unprognostic (2.56e-1)" "unprognostic (3.98e-3)" "unprognostic (1.17e-1)" 6.7 5.1 4.3 1.3 5.0 0.9 7.9 7.0 6.7 23.0 3.0 30.0 3.0 5.0 4.5 58.5 20.0 6.4 6.3 3.6 3.4 69.7 21.1 7.9 0.8 4.1 2.7 11.8 16.1 2.0 16.5 0.5 4.0 20.9 7.2 8.1 40.3 1.1 7.0 8.0 14.7 0.8 1.4 6.1 9.8 8.5 4.2 0.8 16.2 1.0 1.4 21.0 26.0 5.0 0.9 0.0 0.2 0.7 0.4 0.0 0.7 0.0 0.2 0.0 0.1 0.0 3.7 0.1 0.7 0.0 0.2 1.5 0.1 0.0 0.1 1.3 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.4 0.1 0.7 3.9 0.1 1.0 0.1 1.1 0.1 3.6 1.3 0.4 0.0 28.1 0.2 0.5 0.2 0.0 0.0 0.2 0.8 1.0 0.1 1.3 1.7 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.0 7.0 6.7 3.6 3.4 4.1 2.7 4.0 1.4 4.2 5.0 0.9 35.3 16.7 16.6 0.5 1.8 10.0 6.4 0.6 19.9 3.2 1.5 0.7 14.3 43.7 22.0 35.5 0.1 0.2 53.2 1.9 55.5 0.1 3.5 1.3 1.7 13.8 5.3 7.5 9.9 0.1 1.8 13.3 6.2 1.3 5.3 3.3 7.3 0.5 11.8 7.7 7.3 152.5 1.0 0.8 0.4 5.3 1.1 3.6 1.0 0.0 4.7 0.0 5.0 3.0 12.2 16.9 6.4 1.7 14.2 16.9 3.3 66.5 20.5 0.0 8.8 3.3 1.3 1.3 4.3 1.8 0.0 1.7 1.0 15.2 84.4 MUC3A MUC3 ENSG00000169894 "Mucin 3A, cell surface associated" Q02505 7 100949534-100968347 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 13.8;intestine: 41.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 220.6;Intestinal goblet cells: 114.2;Paneth cells: 157.1;Proximal enterocytes: 360.1;Undifferentiated cells: 129.5" "Group enriched" "Detected in many" 5 "colorectal cancer: 16.4;pancreatic cancer: 14.0;stomach cancer: 29.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 7.3;CAPAN-2: 2.4;MCF7: 1.6;OE19: 3.7" "Region enriched" "Detected in many" 7 "cerebellum: 16.5" "HPA010871, HPA047868" Uncertain Uncertain "Cell Junctions" "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Cell Junctions" "HPA010871: AB_1854201, HPA047868: " "unprognostic (1.12e-2)" "unprognostic (3.78e-2)" "unprognostic (1.75e-1)" "unprognostic (4.22e-3)" "unprognostic (2.91e-1)" "unprognostic (5.16e-2)" "unprognostic (2.06e-1)" "unprognostic (5.29e-3)" "unprognostic (2.87e-1)" "unprognostic (1.33e-1)" "unprognostic (7.01e-2)" "unprognostic (2.99e-1)" "unprognostic (6.50e-3)" "unprognostic (8.73e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (4.51e-2)" 1.0 0.0 0.0 1.3 0.0 0.0 0.7 0.0 0.6 0.0 0.0 9.4 41.7 0.0 0.0 0.0 0.0 13.8 3.2 0.0 0.8 0.2 8.7 0.2 0.3 0.0 0.3 0.0 0.5 0.8 0.0 0.0 0.0 3.1 11.9 0.0 0.1 0.0 5.0 0.1 33.5 0.8 0.0 0.1 2.7 0.1 0.1 9.9 0.8 0.5 0.3 0.4 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 7.3 2.4 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.6 0.0 0.0 1.0 3.7 0.0 0.0 0.0 0.2 0.3 0.0 0.5 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.2 0.0 27.2 0.0 0.0 0.0 1.0 0.4 2.1 28.6 0.0 1.8 0.0 0.7 0.0 220.6 0.0 18.8 0.8 0.0 0.1 0.8 10.3 0.0 0.1 28.8 1.1 0.4 15.8 0.0 0.0 0.0 0.4 5.3 0.3 0.0 0.0 114.2 0.0 0.8 0.0 0.4 0.3 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 28.9 157.1 0.0 0.0 65.7 360.1 0.3 0.0 0.0 0.0 0.4 6.4 0.8 6.8 0.0 0.1 0.3 0.4 0.0 129.5 21.3 MUC5AC MUC5 ENSG00000215182 "Mucin 5AC, oligomeric mucus/gel-forming" P98088 11 1157953-1201138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 101 "stomach 1: 185.1" "Cell type enriched" "Detected in some" 248 "Gastric mucus-secreting cells: 10434.9" "Group enriched" "Detected in many" 4 "pancreatic cancer: 25.3;stomach cancer: 61.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "A549: 19.9;OE19: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002774, CAB009395, HPA040615" Enhanced "Secreted to digestive system" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB002774: , CAB009395: AB_2146854, HPA040615: AB_2677042" "unprognostic (2.10e-2)" "unprognostic (1.11e-1)" "unprognostic (1.27e-1)" "unprognostic (3.14e-2)" "unprognostic (1.72e-2)" "unprognostic (2.51e-2)" "unprognostic (4.56e-2)" "unprognostic (6.49e-2)" "unprognostic (2.44e-2)" "unprognostic (1.30e-3)" "unprognostic (8.46e-2)" "unprognostic (5.83e-4)" "unprognostic (1.84e-1)" "unprognostic (9.21e-3)" "unprognostic (4.07e-1)" "unprognostic (1.37e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 185.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 13.5 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 17.4 0.0 0.1 5.4 0.0 0.0 0.1 0.0 2.7 0.0 42.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.8 0.0 2.8 10434.9 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 4.1 0.0 0.0 0.2 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.1 0.0 30.0 8.9 0.0 0.0 10.0 0.0 0.0 0.0 1.3 0.0 0.4 0.0 0.0 0.1 7.9 0.0 0.0 28.1 MUC5B "MG1, MUC5" ENSG00000117983 "Mucin 5B, oligomeric mucus/gel-forming" Q9HC84 11 1223066-1262172 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "salivary gland: 2621.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 443.2;Distal enterocytes: 158.4;Intestinal goblet cells: 210.1;Undifferentiated cells: 183.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "OE19: 113.9;PC-3: 120.0" "Not detected" "Not detected" "HPA008246, CAB009396" Enhanced Supported Vesicles "Secreted in other tissues" NA NA 1300000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB009396: AB_2282256, HPA008246: AB_1854203" "unprognostic (2.01e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (2.76e-3)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (4.89e-2)" "unprognostic (7.80e-3)" "unprognostic (3.75e-1)" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (8.95e-2)" "unprognostic (2.57e-7)" "unprognostic (2.71e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (8.13e-2)" 0.1 0.7 0.2 2.0 0.1 0.0 1.3 0.0 0.4 229.4 0.0 58.0 0.1 0.3 0.0 101.0 1.1 221.3 0.1 0.0 0.0 0.1 2.4 7.5 0.0 0.1 0.0 0.1 9.8 0.0 0.4 0.0 0.0 0.6 17.1 0.0 2621.9 0.0 0.3 0.4 2.6 0.6 0.0 0.0 6.9 0.3 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.1 0.2 0.0 113.9 120.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 2.3 0.0 0.0 6.7 0.6 0.0 6.4 4.3 12.4 443.2 64.0 0.0 0.0 0.1 0.0 158.4 0.0 0.9 0.0 1.4 0.8 0.9 24.5 0.0 0.1 0.0 0.1 1.1 12.8 7.2 4.5 0.0 0.0 1.2 0.2 0.0 0.0 210.1 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 53.4 0.0 1.4 1.3 0.1 0.2 24.5 0.0 0.0 0.0 3.0 0.0 0.5 1.6 0.0 0.1 0.7 0.1 183.1 1.1 MUC6 ENSG00000184956 "Mucin 6, oligomeric mucus/gel-forming" Q6W4X9 11 1012823-1036718 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "pancreas: 171.2;stomach 1: 409.9" "Cell type enriched" "Detected in some" 4 "Gastric mucus-secreting cells: 278.8" "Group enriched" "Detected in many" 4 "pancreatic cancer: 42.9;stomach cancer: 58.0" "Region enhanced" "Detected in single" "amygdala: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "OE19: 1.7" "Not detected" "Not detected" CAB002165 Enhanced "Secreted to digestive system" NA NA 75000 "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB002165: AB_442114" "unprognostic (1.90e-2)" "unprognostic (1.00e-1)" "unprognostic (5.21e-3)" "unprognostic (1.56e-3)" "unprognostic (1.04e-1)" "unprognostic (5.17e-3)" "unprognostic (2.17e-1)" "unprognostic (1.48e-1)" "unprognostic (1.65e-2)" "unprognostic (2.63e-1)" "unprognostic (9.46e-2)" "unprognostic (8.62e-2)" "unprognostic (3.17e-3)" "unprognostic (1.95e-1)" "unprognostic (2.39e-1)" "unprognostic (4.72e-2)" "unprognostic (5.23e-2)" 0.5 0.2 1.2 0.0 0.6 0.0 0.9 0.3 0.5 26.3 0.0 3.0 15.6 2.1 0.9 5.2 2.5 0.3 0.2 0.8 0.0 2.6 5.4 0.2 0.0 0.0 0.0 0.2 171.2 0.0 0.2 0.0 0.0 4.3 0.0 0.0 0.1 28.0 0.1 0.1 0.1 0.0 0.0 0.3 409.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.3 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 11.3 2.8 1.7 54.3 0.0 9.2 0.0 0.0 0.2 0.1 0.0 12.2 0.1 0.5 0.1 0.1 0.0 0.0 1.2 19.1 0.0 0.1 278.8 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 59.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 MUC7 "FLJ27047, MG2" ENSG00000171195 "Mucin 7, secreted" Q8TAX7 4 70430492-70482997 "Disease related genes, Predicted secreted proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 875 "salivary gland: 26019.1" "Cell type enriched" "Detected in some" 12 "Melanocytes: 12.4" "Group enriched" "Detected in some" 12 "head and neck cancer: 8.1;melanoma: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA006411 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 48: Smooth muscle cells - ECM organization" "HPA006411: AB_1854204" "unprognostic (5.49e-2)" "unprognostic (3.20e-1)" "unprognostic (1.06e-1)" 1.2 5.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.7 0.0 1.0 0.0 0.1 0.0 2.1 0.0 0.0 6.6 0.0 0.0 1.0 3.7 0.6 0.0 0.0 0.7 6.5 29.7 0.0 1.9 3.2 0.0 0.8 0.0 0.0 26019.1 0.0 2.6 3.6 1.5 0.0 0.0 1.0 1.1 1.5 0.2 0.0 1.3 0.1 0.4 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 12.4 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MUCL1 SBEM ENSG00000172551 "Mucin like 1" Q96DR8 12 54830518-54896008 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 3241.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4494.5;Breast myoepithelial cells: 1273.2;Melanocytes: 1060.1" "Cancer enriched" "Detected in many" 30 "breast cancer: 298.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;hTCEpi: 1.3;MCF7: 2.1;SK-BR-3: 4.8;SuSa: 3.3" HPA039093 Enhanced "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA039093: AB_10795577" "unprognostic (2.26e-1)" "unprognostic (3.38e-1)" "unprognostic (1.90e-1)" "unprognostic (1.47e-1)" "unprognostic (2.53e-1)" "unprognostic (8.34e-3)" "unprognostic (5.55e-2)" "unprognostic (2.00e-1)" "unprognostic (3.11e-2)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (4.04e-1)" "unprognostic (9.90e-2)" 35.4 0.4 0.2 1.1 0.4 0.0 3241.2 0.2 0.6 1.3 0.1 1.8 0.0 0.2 1.5 0.4 2.1 0.2 2.6 0.3 0.2 2.3 1.0 1.1 0.1 0.2 0.2 0.3 0.3 0.0 0.3 0.4 0.2 1.1 0.0 0.0 207.3 0.0 1.9 762.2 0.3 0.1 0.2 0.2 0.7 1.2 0.2 2.4 0.2 0.0 0.0 1.2 3.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.8 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.2 0.6 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.5 10.4 0.0 1.1 0.0 3.8 188.4 0.4 2.1 0.0 0.0 4494.5 1273.2 0.1 0.0 3.4 0.0 0.0 0.0 12.9 0.0 3.9 0.0 0.0 1.8 0.0 3.4 0.0 0.0 1.4 0.2 0.0 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 2.0 0.0 14.1 0.2 0.0 45.5 1060.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 5.9 0.0 0.1 2.6 0.0 0.0 0.0 6.1 0.2 0.6 0.0 10.1 0.0 2.5 0.1 0.0 3.8 MVB12A "FAM125A, FLJ32495" ENSG00000141971 "Multivesicular body subunit 12A" Q96EY5 19 17405722-17433724 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041885, HPA042231" Approved Supported Vesicles NA No "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041885: AB_10964218, HPA042231: AB_10961043" "unprognostic (1.34e-2)" "prognostic favorable (3.26e-4)" "unprognostic (1.48e-1)" "unprognostic (2.35e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" "unprognostic (5.96e-3)" "unprognostic (8.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.77e-1)" "unprognostic (9.93e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-1)" "unprognostic (2.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.33e-2)" 21.3 28.4 10.5 17.3 11.5 18.2 21.4 11.4 12.3 18.6 11.8 16.7 29.1 17.3 7.4 29.5 22.0 18.7 13.1 10.0 10.3 20.2 19.9 15.5 21.7 14.0 11.0 34.0 20.0 22.2 7.4 19.2 11.6 13.7 11.6 1.2 24.2 17.5 14.4 24.7 22.0 11.6 12.3 22.3 20.9 5.2 11.4 24.0 21.2 12.4 19.3 17.0 18.0 13.5 51.2 23.4 12.1 33.9 15.7 28.8 71.1 18.3 28.4 33.8 40.8 20.1 60.5 32.7 52.7 28.2 28.8 25.5 19.5 35.5 9.0 37.6 60.7 9.5 41.8 44.0 50.3 13.0 29.1 28.2 28.5 29.1 18.0 25.5 40.7 29.9 26.8 65.2 15.6 32.2 24.6 26.2 17.0 40.8 63.9 34.7 14.8 53.1 32.4 21.2 25.3 40.7 19.6 30.2 77.6 10.9 40.1 30.9 21.7 31.5 18.4 35.1 20.5 59.3 72.9 35.0 34.1 49.3 38.9 57.4 61.7 42.9 33.0 66.9 31.0 23.3 34.0 32.0 60.5 29.8 28.0 27.5 36.0 38.2 53.4 53.3 57.2 36.2 10.5 11.5 11.4 12.3 10.0 10.3 14.0 11.0 11.6 12.3 11.4 13.5 67.5 9.6 8.2 5.9 16.4 39.0 41.4 65.1 42.1 5.3 53.6 61.8 5.6 48.6 33.5 46.0 6.2 60.7 18.1 85.0 54.8 78.7 13.5 30.1 26.8 47.7 26.5 8.4 2.2 48.4 99.0 38.6 43.3 30.2 21.6 45.7 62.4 28.0 72.3 3.3 3.2 48.5 50.8 44.9 30.8 16.3 43.5 31.2 32.0 11.2 46.7 32.7 19.6 4.0 7.3 63.4 84.1 47.0 23.5 19.0 104.4 61.3 36.4 13.8 6.6 22.8 40.9 11.8 12.3 58.3 43.9 40.6 21.2 44.3 57.1 45.0 MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.5;Collecting duct cells: 31.3;Exocrine glandular cells: 60.7;Fibroblasts: 56.0;Pancreatic endocrine cells: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 31.4;BJ hTERT+: 125.8;fHDF/TERT166: 59.8;HaCaT: 52.4;HSkMC: 24.7" "Low region specificity" "Detected in all" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" NA NA 2600000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" 12.0 10.3 0.2 9.4 0.3 0.0 13.5 0.0 0.4 35.0 0.0 7.5 4.4 6.8 2.7 9.4 3.0 8.0 11.1 0.2 0.1 5.3 4.5 5.3 1.6 0.3 0.3 2.9 16.1 1.7 0.9 5.8 0.2 7.3 10.4 0.0 6.1 10.4 1.5 29.6 4.6 15.9 0.5 3.6 10.3 0.1 1.2 5.7 9.8 5.1 3.7 19.9 7.2 0.1 0.0 0.0 0.8 0.0 0.2 31.4 0.0 19.6 125.8 0.2 0.2 0.0 0.6 0.0 1.7 59.8 0.2 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.7 5.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.1 0.3 0.3 0.2 0.5 1.2 0.1 10.3 0.0 0.0 0.0 0.0 38.5 7.1 10.5 20.5 0.0 2.0 4.6 1.9 0.0 3.7 31.3 0.0 0.1 0.3 0.9 0.0 2.2 0.0 1.0 8.4 4.6 0.0 0.0 0.7 60.7 0.7 56.0 0.0 1.6 0.0 0.0 10.8 0.1 0.3 0.0 1.1 0.0 0.0 0.3 16.9 0.0 0.0 0.3 17.8 4.7 0.6 0.0 0.0 0.5 0.2 42.8 0.0 1.5 0.1 0.2 0.1 0.1 1.0 0.2 0.0 7.3 9.8 0.0 0.0 5.5 21.7 0.3 1.1 0.9 0.4 2.0 MYCBP2 "FLJ10106, KIAA0916, PAM, PHR1" ENSG00000005810 "MYC binding protein 2" O75592 13 77044657-77327094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 425.4;Inhibitory neurons: 471.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 110.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058807 Supported Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Vesicles, Cytosol" "HPA058807: AB_2732627" "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-2)" "unprognostic (8.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (6.42e-2)" "prognostic favorable (5.01e-5)" "unprognostic (2.63e-1)" "unprognostic (9.84e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" 69.9 22.2 42.3 19.0 46.2 32.8 49.3 37.3 52.4 43.4 18.8 29.4 9.0 27.2 29.8 45.9 29.2 12.5 32.9 48.6 35.9 22.6 24.5 28.3 40.0 34.6 29.6 43.1 30.9 14.9 32.3 10.9 36.9 28.0 12.5 28.9 29.1 13.3 26.5 79.7 34.8 11.9 30.1 56.4 24.9 26.3 33.9 34.6 27.2 18.1 37.8 30.4 41.5 38.7 21.6 10.8 12.9 14.1 62.9 27.9 7.5 13.4 19.8 11.5 14.7 9.7 11.0 61.4 8.3 26.6 11.2 19.5 22.4 24.7 15.5 24.5 22.2 52.2 22.2 20.1 21.4 110.8 17.7 31.5 20.2 10.6 20.8 11.4 26.5 22.3 11.3 18.8 20.7 13.1 30.5 74.3 6.8 28.7 13.6 34.2 13.1 15.0 19.6 21.1 20.2 9.4 16.2 23.1 12.8 13.0 8.6 83.8 35.0 10.9 9.1 7.3 13.0 20.3 15.0 42.7 22.1 89.2 11.3 1.4 2.0 2.0 3.2 2.1 2.8 4.9 3.6 2.8 1.9 4.3 4.1 3.2 1.8 2.8 1.6 2.7 4.5 1.4 42.3 46.2 37.3 52.4 48.6 35.9 34.6 29.6 36.9 30.1 33.9 38.7 92.2 38.5 52.2 158.7 170.3 82.3 39.9 32.6 63.7 229.3 36.8 38.4 69.7 25.8 30.9 35.0 104.3 46.1 109.2 14.2 1.9 26.1 56.0 50.9 61.1 83.8 32.6 46.9 425.4 33.1 31.5 80.6 38.2 66.6 48.2 34.0 44.6 52.4 41.8 218.7 471.3 19.7 26.4 106.9 48.2 23.4 65.9 100.4 32.0 282.9 116.7 121.5 120.5 338.8 212.5 30.2 15.8 96.3 121.9 53.7 15.2 13.2 19.5 94.8 105.2 76.7 76.0 81.5 71.6 129.1 150.7 43.9 121.5 67.4 28.1 42.4 MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697895-152724567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.6" "Group enriched" "Detected in some" 5 "Adipocytes: 123.0;Endothelial cells: 141.3;Hepatic stellate cells: 230.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 248 "granulocytes: 30.7" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 124.6;TIME: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Approved Nucleoplasm,Vesicles NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" 26.6 3.2 6.8 5.2 6.9 1.2 21.4 6.9 10.2 9.0 5.2 6.1 3.5 10.1 4.5 4.6 9.2 10.5 17.1 6.3 7.1 6.6 13.1 15.6 6.2 7.7 6.9 3.6 2.7 4.3 2.2 20.7 8.6 4.4 5.8 1.0 3.7 3.8 12.8 4.7 5.6 12.4 6.8 49.6 4.5 1.8 10.0 2.5 12.2 20.5 3.0 8.1 7.3 7.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 17.7 0.1 0.0 0.2 0.0 0.1 0.0 23.0 0.3 0.0 0.7 0.1 0.1 0.0 0.2 0.2 0.3 0.0 124.6 0.0 0.3 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 104.4 0.5 0.8 1.5 0.0 1.1 0.0 15.6 0.0 0.0 0.0 0.9 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.6 6.8 6.9 6.9 10.2 6.3 7.1 7.7 6.9 8.6 6.8 10.0 7.5 123.0 0.0 5.2 0.7 0.8 7.1 0.2 0.1 2.8 0.2 0.4 0.9 3.1 2.8 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 1.3 0.2 141.3 0.0 13.7 0.1 0.2 0.0 4.0 0.0 0.1 1.3 0.0 230.6 2.1 0.1 0.0 0.1 0.0 0.0 7.3 7.3 3.7 0.3 13.3 14.2 30.9 0.1 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.5 0.0 0.0 17.7 0.0 0.0 1.5 2.2 0.1 0.1 0.5 5.5 0.0 0.9 0.5 0.0 0.7 MYDGF "C19orf10, IL-25, IL-27, IL25, IL27, IL27w, R33729_1, SF20" ENSG00000074842 "Myeloid derived growth factor" Q969H8 19 4641374-4670362 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 768.1;Plasma cells: 857.6;Syncytiotrophoblasts: 581.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 1043.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041872, HPA046744" Approved "Secreted to blood" NA NA 285000 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA041872: AB_2677718, HPA046744: AB_2679783" "unprognostic (3.14e-1)" "unprognostic (1.32e-2)" "unprognostic (1.73e-1)" "prognostic favorable (6.50e-7)" "unprognostic (4.14e-1)" "unprognostic (1.35e-1)" "unprognostic (1.08e-2)" "unprognostic (1.71e-1)" "unprognostic (5.11e-2)" "unprognostic (4.56e-2)" "unprognostic (8.19e-2)" "unprognostic (4.54e-2)" "prognostic unfavorable (4.99e-12)" "unprognostic (4.42e-1)" "unprognostic (3.24e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" 84.7 94.2 42.5 83.8 43.5 92.0 73.2 44.4 48.7 79.1 47.6 81.4 75.7 75.1 114.6 67.5 71.0 44.1 66.3 43.1 48.1 70.8 259.5 91.7 61.9 45.7 44.0 72.1 210.0 41.7 126.1 76.1 45.8 84.2 65.5 13.0 135.6 52.8 24.7 59.3 71.1 52.9 45.5 123.0 94.5 54.5 45.0 30.8 75.4 15.1 45.5 74.3 63.3 50.2 250.5 118.7 74.6 189.8 228.0 190.2 133.0 449.6 378.1 210.8 263.8 194.9 155.8 145.0 206.5 455.4 171.9 122.7 88.6 157.7 121.8 137.7 152.0 87.6 212.7 250.0 353.9 310.9 201.6 159.0 187.8 154.6 292.3 263.0 233.0 78.8 155.4 1043.7 194.9 134.4 83.9 174.1 94.5 235.3 417.1 80.0 126.3 701.0 169.1 114.2 114.1 117.0 151.0 189.1 227.5 64.2 111.4 366.6 268.9 162.8 135.1 449.2 325.9 505.8 229.6 122.2 401.8 405.8 260.1 156.8 216.6 82.6 148.7 232.2 151.6 123.6 118.7 121.1 264.0 101.0 99.8 107.0 13.8 151.5 209.0 426.0 96.3 225.2 42.5 43.5 44.4 48.7 43.1 48.1 45.7 44.0 45.8 45.5 45.0 50.2 134.4 44.8 68.1 4.6 185.1 0.0 160.1 0.0 46.1 31.0 153.8 133.9 6.6 110.1 18.6 77.3 4.2 284.0 135.6 39.8 43.0 355.9 8.7 65.9 168.2 131.9 31.5 55.3 7.3 351.1 768.1 177.0 92.8 158.8 16.4 135.8 126.7 207.3 415.6 26.9 9.6 96.2 0.0 118.8 0.0 12.8 140.5 155.4 0.0 9.4 250.8 51.3 116.4 8.0 10.6 401.8 71.3 91.0 857.6 342.0 182.9 86.8 9.5 32.7 92.1 92.7 157.1 183.2 125.1 64.4 0.0 581.6 84.9 145.5 101.0 260.7 MYG1 "C12orf10, Gamm1, MYG" ENSG00000139637 "MYG1 exonuclease" Q9HB07 12 53299695-53307177 "Disease related genes, Predicted intracellular proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 16.4;Cytotrophoblasts: 38.4;Extravillous trophoblasts: 60.7;Hofbauer cells: 70.1;Syncytiotrophoblasts: 25.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038626, HPA038627" Approved Supported Supported Nucleoplasm "Intracellular and membrane" NA NA 20000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA038626: AB_10674692, HPA038627: AB_2676123" "unprognostic (5.33e-2)" "unprognostic (4.41e-2)" "unprognostic (6.77e-2)" "unprognostic (2.44e-2)" "unprognostic (3.59e-1)" "unprognostic (7.56e-2)" "unprognostic (1.61e-3)" "unprognostic (2.73e-1)" "unprognostic (1.97e-1)" "unprognostic (3.58e-2)" "unprognostic (2.71e-2)" "unprognostic (1.39e-1)" "unprognostic (2.81e-1)" "unprognostic (6.41e-2)" "unprognostic (2.18e-1)" "unprognostic (2.16e-1)" "unprognostic (1.61e-1)" 33.8 35.8 40.0 18.0 41.4 20.8 31.8 45.5 66.7 35.0 40.4 33.2 18.6 32.8 21.2 24.9 35.7 20.7 32.0 39.7 44.0 36.9 28.0 20.8 22.5 45.4 45.6 40.6 45.4 31.4 29.0 15.4 46.8 25.3 14.9 17.3 26.1 20.8 48.0 31.3 21.1 19.8 41.9 20.5 33.2 104.8 43.5 22.7 30.6 26.3 19.9 34.4 27.5 42.2 42.3 78.0 33.8 53.5 35.1 52.4 3.9 27.3 43.6 62.0 44.1 74.5 44.9 40.6 63.2 38.3 35.1 46.6 46.8 60.8 32.8 34.0 78.9 41.7 60.4 91.5 81.0 43.8 27.1 49.7 40.1 57.4 58.1 61.7 53.8 46.8 2.4 81.0 41.5 164.8 58.9 71.0 55.0 42.7 73.9 54.9 31.9 93.6 53.7 41.0 66.7 63.9 30.9 60.3 68.3 19.3 94.8 42.0 37.3 60.3 55.8 43.7 43.9 73.3 81.8 43.8 75.7 37.2 47.6 24.2 55.0 26.1 35.8 44.4 52.6 49.9 46.3 35.5 63.5 41.5 47.8 44.3 14.6 42.4 32.9 39.8 69.5 50.1 40.0 41.4 45.5 66.7 39.7 44.0 45.4 45.6 46.8 41.9 43.5 42.2 13.8 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 38.4 6.8 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 60.7 9.7 0.0 0.0 0.0 0.0 0.0 0.0 70.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 25.9 1.5 0.0 0.0 0.0 MYL1 ENSG00000168530 "Myosin light chain 1" P05976 2 210290150-210315174 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 88 "skeletal muscle: 21805.2;tongue: 15591.3" "Cell type enriched" "Detected in some" 246 "Skeletal myocytes: 492.9" "Group enriched" "Detected in some" 18 "head and neck cancer: 36.0;prostate cancer: 12.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HSkMC: 51.4" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.0" "Low region specificity" "Detected in all" "HPA046859, HPA063034, HPA073827" Enhanced "Intracellular and membrane" NA NA 21000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "HPA046859: AB_2679842, HPA063034: AB_2684927, HPA073827: " "prognostic unfavorable (6.59e-4)" "unprognostic (1.88e-1)" 2.3 0.5 0.1 0.0 0.1 0.0 3.3 0.0 0.1 0.1 0.0 1.1 0.0 0.5 0.0 212.7 0.0 0.0 2.0 0.1 0.0 0.7 1.0 0.9 0.0 0.0 0.0 0.6 1.1 0.0 0.4 0.0 0.0 164.2 0.0 0.0 170.2 0.0 21805.2 4.0 0.7 0.0 0.0 0.4 0.7 0.5 0.0 7.4 2.3 15591.3 0.9 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 11.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 492.9 2.0 0.1 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.1 MYL3 "CMH8, MLC1SB, MLC1V, VLC1" ENSG00000160808 "Myosin light chain 3" P08590 3 46835111-46882172 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 9155.0;skeletal muscle: 5135.3;tongue: 2074.2" "Cell type enriched" "Detected in some" 53 "Cardiomyocytes: 3626.2" "Group enriched" "Detected in many" 4 "head and neck cancer: 3.0;prostate cancer: 3.4;renal cancer: 8.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 8.6;HSkMC: 8.7;RPTEC TERT1: 34.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA016564, CAB018662, HPA046859, HPA063034" Enhanced Approved Nucleoli,Mitochondria NA NA 7300000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoli, Mitochondria" "CAB018662: AB_627952, HPA016564: AB_1854244, HPA046859: AB_2679842, HPA063034: AB_2684927" "unprognostic (3.11e-1)" "unprognostic (2.64e-2)" "unprognostic (5.55e-2)" "unprognostic (1.51e-1)" "unprognostic (1.77e-1)" "unprognostic (4.44e-2)" "unprognostic (9.67e-3)" "unprognostic (3.37e-2)" "unprognostic (4.72e-3)" "unprognostic (3.63e-2)" "unprognostic (1.08e-1)" "unprognostic (7.88e-2)" "prognostic favorable (1.22e-8)" "unprognostic (1.16e-3)" "unprognostic (9.45e-3)" "unprognostic (7.18e-5)" "unprognostic (2.53e-3)" 5.8 4.1 11.3 0.9 11.1 1.5 8.9 11.4 14.8 6.7 8.4 2.5 1.6 3.3 3.4 157.0 4.2 3.6 9155.0 11.0 12.8 50.3 4.1 5.7 3.3 15.2 13.0 5.2 2.7 1.3 1.7 4.7 12.1 25.1 0.8 1.9 19.6 1.5 5135.3 4.0 2.3 2.0 13.2 7.9 2.1 2.3 12.6 0.7 2.4 2074.2 0.5 2.4 4.7 13.2 0.5 0.7 0.4 0.3 4.4 1.5 3.6 0.7 0.4 0.4 0.6 8.6 0.8 1.6 1.4 0.1 0.2 0.5 0.4 0.1 0.7 0.3 0.1 0.8 2.6 0.3 0.7 0.9 0.8 8.7 0.2 0.3 0.1 0.2 0.1 0.5 0.4 1.2 0.2 1.2 0.3 0.5 1.0 0.4 0.4 0.9 0.3 0.1 34.2 1.3 0.6 0.4 0.3 0.7 0.1 0.7 0.3 0.5 0.2 1.0 0.8 0.6 0.3 0.5 0.4 0.7 0.3 0.8 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.4 0.1 0.1 0.3 0.0 0.1 0.4 0.0 0.0 11.3 11.1 11.4 14.8 11.0 12.8 15.2 13.0 12.1 13.2 12.6 13.2 0.7 0.0 0.0 1.0 0.0 0.8 0.2 0.0 0.0 0.2 2.3 0.1 3626.2 0.0 0.0 1.8 0.0 0.4 0.0 0.0 54.8 0.0 2.4 0.1 2.2 32.8 0.0 0.0 0.1 0.0 16.4 23.7 0.0 0.0 0.0 0.0 1.1 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.6 12.8 1.2 0.7 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 68.1 0.0 0.4 6.6 27.9 20.4 0.2 0.5 0.0 0.4 0.8 0.4 0.1 0.0 0.0 MYL4 "ALC1, AMLC, GT1, PRO1957" ENSG00000198336 "Myosin light chain 4" P12829 17 47200446-47223679 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Atrial fibrillation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 47 "heart muscle: 6347.0" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 2426.3" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 11.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 9 "dendritic cells: 1.8" "Cell line enriched" "Detected in some" 4 "HEL: 552.8" "Group enriched" "Detected in all" 6 "amygdala: 25.8;cerebral cortex: 88.4;hippocampal formation: 25.2;white matter: 50.9" "Not detected" "Not detected" "HPA046859, HPA051884, HPA063034" Enhanced Approved "Plasma membrane" NA NA 3100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "HPA046859: AB_2679842, HPA051884: AB_2681651, HPA063034: AB_2684927" "unprognostic (2.43e-2)" "unprognostic (9.57e-2)" "unprognostic (2.25e-1)" "unprognostic (5.51e-2)" "unprognostic (2.33e-1)" "unprognostic (4.12e-3)" "unprognostic (5.06e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (6.52e-2)" "unprognostic (2.10e-2)" "unprognostic (7.37e-2)" "unprognostic (1.00e-6)" "unprognostic (1.92e-4)" "unprognostic (2.54e-1)" "unprognostic (6.51e-3)" "unprognostic (1.50e-1)" 2.1 0.5 0.2 0.4 0.3 134.6 2.7 0.2 0.4 0.4 0.4 0.8 0.8 0.8 0.0 0.6 0.5 1.0 6347.0 0.3 0.4 1.3 1.4 9.4 0.9 0.3 0.3 0.8 8.6 0.3 0.5 9.1 0.4 1.1 0.3 42.2 3.0 0.2 3.5 1.2 1.3 0.8 0.2 3.1 3.4 15.5 0.3 2.4 11.0 6.4 0.4 0.9 0.8 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.9 0.3 0.0 0.2 0.0 0.9 0.1 1.6 0.9 0.0 0.4 0.0 0.1 0.0 0.0 3.0 0.2 552.8 0.1 0.0 0.0 0.0 0.3 21.2 0.0 0.3 0.1 0.0 1.0 1.4 133.3 0.3 0.2 0.0 10.0 0.1 0.3 0.0 0.4 0.3 12.9 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 24.3 0.0 0.2 4.5 0.0 0.3 0.1 0.0 0.3 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.2 0.3 0.2 0.4 0.3 0.4 0.3 0.3 0.4 0.2 0.3 0.4 3.2 3.2 0.0 0.0 0.7 0.8 0.0 0.0 0.0 5.5 0.0 0.0 2426.3 0.0 0.0 0.0 64.6 0.5 2.7 0.1 0.0 0.1 23.3 0.1 0.0 23.2 0.0 412.8 0.1 0.0 3.9 150.7 1.5 0.1 0.0 0.3 1.8 0.5 1.9 1.7 0.0 0.8 0.0 0.6 0.6 54.6 3.4 34.0 12.4 0.0 1.5 7.9 4.1 0.0 0.1 0.1 0.0 1.5 0.8 0.0 10.9 0.2 0.0 24.4 0.0 0.6 36.5 9.9 0.5 0.0 0.9 1.4 0.3 0.2 1.0 0.0 MYL6B MLC1SA ENSG00000196465 "Myosin light chain 6B" P14649 12 56152256-56159647 "Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 635.0;tongue: 390.4" "Group enriched" "Detected in all" 4 "Early spermatids: 340.7;Late spermatids: 1215.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 18.4" "Group enriched" "Detected in all" 5 "B-cells: 6.3;dendritic cells: 18.4;T-cells: 14.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038887, HPA046859, HPA063034" Enhanced NA NA 7200000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 25: Spermatids - Spermatogenesis" "HPA038887: AB_10674842, HPA046859: AB_2679842, HPA063034: AB_2684927" "unprognostic (5.25e-2)" "unprognostic (3.18e-1)" "unprognostic (6.29e-3)" "unprognostic (7.39e-2)" "unprognostic (5.37e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (4.66e-2)" "unprognostic (1.26e-1)" "unprognostic (5.15e-2)" "unprognostic (1.02e-3)" "unprognostic (3.48e-1)" "unprognostic (1.53e-1)" "unprognostic (3.56e-3)" "unprognostic (3.42e-2)" "unprognostic (3.00e-1)" "unprognostic (3.83e-2)" 22.7 27.3 133.2 13.8 134.3 17.0 23.8 125.1 177.1 39.5 110.9 23.1 7.5 27.1 34.5 23.4 36.3 27.6 44.8 135.2 133.9 41.4 17.0 16.3 21.9 126.5 128.9 54.3 12.7 77.5 72.0 14.1 130.4 36.2 10.2 23.6 23.1 21.2 635.0 20.4 14.4 22.8 124.0 16.2 18.2 140.0 129.2 43.1 29.3 390.4 25.8 19.0 26.4 125.3 34.1 57.4 152.1 146.4 31.6 112.7 106.0 39.0 170.0 150.8 146.4 41.3 55.4 56.6 83.6 83.9 57.8 19.1 72.2 94.4 80.6 102.9 104.9 59.6 54.8 73.6 99.5 43.7 40.0 189.4 37.6 140.0 54.1 320.2 165.6 134.8 64.2 56.6 126.0 44.5 121.0 145.3 128.3 32.1 97.5 125.7 94.4 75.1 117.0 22.7 139.3 204.6 43.1 52.6 80.4 110.6 43.0 74.0 93.2 88.3 75.1 46.1 84.8 79.9 49.2 47.5 94.7 43.9 98.8 0.9 2.8 0.9 2.0 2.7 1.1 6.3 4.0 3.3 6.4 4.0 3.0 2.5 2.1 2.3 1.1 18.4 14.9 4.3 133.2 134.3 125.1 177.1 135.2 133.9 126.5 128.9 130.4 124.0 129.2 125.3 29.4 67.3 32.4 13.4 28.2 33.1 54.6 72.4 67.7 59.6 67.4 101.7 17.6 38.6 30.6 110.3 25.0 34.2 24.1 21.5 150.6 50.4 340.7 83.0 58.9 44.0 157.4 24.6 18.9 20.2 68.3 55.3 26.0 93.1 12.7 134.9 53.9 32.2 43.5 33.7 23.7 35.0 46.8 22.3 25.0 1215.9 80.8 19.1 40.9 6.5 47.7 149.9 4.1 11.6 7.6 26.9 19.5 66.5 44.2 39.4 28.0 156.4 23.9 51.4 52.6 63.2 53.0 126.4 54.4 71.3 25.4 22.6 15.6 52.2 32.7 47.9 MYMX MINION ENSG00000262179 "Myomixer, myoblast fusion factor" A0A1B0GTQ4 6 44216926-44218234 "Predicted intracellular proteins" Myogenesis "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "adipose tissue: 7.7;breast: 6.9;pancreas: 5.6;stomach 1: 2.3" "Group enriched" "Detected in some" 4 "Adipocytes: 5.5;Distal tubular cells: 3.9;Exocrine glandular cells: 2.2;Extravillous trophoblasts: 1.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 106 "plasmacytoid DC: 10.6" "Lineage enriched" "Detected in single" 106 "dendritic cells: 10.6" "Cell line enriched" "Detected in some" 31 "RH-30: 134.6" "Not detected" "Not detected" HPA051451 Supported Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Mitochondria, Cytosol" "HPA051451: " "unprognostic (1.24e-1)" "unprognostic (8.55e-2)" "unprognostic (6.86e-2)" "unprognostic (6.51e-3)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-2)" "unprognostic (2.10e-3)" "unprognostic (4.32e-1)" "unprognostic (1.77e-1)" "unprognostic (8.71e-2)" "unprognostic (2.70e-2)" "unprognostic (2.01e-4)" "unprognostic (1.63e-2)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "unprognostic (2.67e-1)" 7.7 0.1 0.0 0.2 0.0 0.0 6.9 0.1 0.1 0.2 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.5 1.0 0.0 0.0 0.7 0.1 0.4 0.6 0.1 0.0 0.1 5.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.0 0.4 0.9 0.5 0.1 0.0 0.8 2.3 0.4 0.0 0.8 0.4 0.2 0.3 0.5 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 134.6 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.2 1.6 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 MYOC "GLC1A, JOAG1, TIGR" ENSG00000034971 Myocilin Q99972 1 171635417-171652688 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 110.8" "Cell type enriched" "Detected in some" 6 "Fibroblasts: 244.4" "Cancer enriched" "Detected in many" 6 "melanoma: 13.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA027364 Uncertain "Secreted to extracellular matrix" NA NA 25000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "HPA027364: AB_10602036" "unprognostic (2.02e-2)" "unprognostic (4.65e-2)" "unprognostic (4.44e-2)" "unprognostic (6.29e-2)" "unprognostic (1.43e-1)" "unprognostic (2.33e-2)" "unprognostic (3.42e-2)" "unprognostic (3.02e-2)" "unprognostic (2.82e-2)" "unprognostic (2.54e-1)" "unprognostic (1.94e-4)" "unprognostic (5.35e-2)" "unprognostic (1.87e-1)" "unprognostic (3.87e-2)" "unprognostic (1.24e-1)" 47.1 1.1 0.0 0.0 0.0 0.0 19.2 0.2 0.0 1.8 0.0 13.0 3.5 16.5 4.9 19.6 15.3 1.5 18.3 0.0 0.1 0.2 0.1 7.4 0.1 0.5 0.1 1.3 3.0 0.1 0.2 0.2 0.2 5.3 3.5 0.0 14.0 6.4 33.8 4.7 4.8 2.9 0.0 0.0 50.2 1.4 0.1 14.1 28.7 110.8 0.2 22.6 9.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.1 0.2 0.0 0.1 0.1 12.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.1 3.1 0.0 0.0 0.1 0.0 0.0 244.4 11.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.1 1.0 8.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.6 2.4 0.1 0.0 0.0 0.0 0.0 0.0 15.1 6.3 0.1 0.1 1.1 0.0 0.0 1.1 0.2 0.0 0.0 MYORG "KIAA1161, NET37" ENSG00000164976 "Myogenesis regulating glycosidase (putative)" Q6NSJ0 9 34366666-34376898 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 55.5;Exocrine glandular cells: 11.8;Pancreatic endocrine cells: 10.3;Proximal tubular cells: 9.2;Syncytiotrophoblasts: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 35.4;SK-BR-3: 56.8;T-47d: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060533, HPA067487" Enhanced Approved Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA060533: AB_2684311, HPA067487: AB_2685848" "unprognostic (6.56e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (2.44e-1)" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.68e-3)" "unprognostic (1.91e-3)" "unprognostic (3.20e-1)" "prognostic favorable (1.20e-13)" "unprognostic (4.08e-3)" "unprognostic (3.68e-1)" "unprognostic (3.09e-1)" "unprognostic (1.00e-3)" 8.1 6.2 30.6 3.4 30.3 2.0 3.4 27.1 31.5 1.7 16.8 19.0 27.3 2.7 1.9 5.3 4.5 6.1 3.9 28.4 28.2 14.5 41.5 3.2 1.5 34.0 33.5 1.0 11.1 1.5 5.5 19.8 28.7 3.2 16.2 3.4 5.6 5.2 84.2 3.7 25.8 4.4 24.5 1.4 15.0 1.3 31.8 1.1 1.9 39.2 1.8 3.1 2.4 24.2 8.1 5.5 9.2 5.6 3.8 1.2 19.7 1.4 1.1 0.8 1.3 13.9 8.3 4.4 15.9 1.4 4.0 16.4 6.7 15.5 1.1 1.4 3.6 0.8 24.6 35.4 0.5 0.8 2.7 1.8 7.2 2.6 3.0 4.3 3.8 3.3 1.1 4.2 2.0 13.4 2.5 1.2 5.5 27.4 4.4 4.0 4.6 1.3 4.9 2.9 1.3 13.0 10.8 56.8 0.9 7.8 52.8 1.3 3.2 1.8 11.0 1.6 3.5 2.8 6.5 1.6 1.6 3.1 1.6 0.4 0.1 0.2 0.7 0.1 0.5 0.2 0.4 0.4 0.0 0.2 0.2 0.3 0.3 0.4 0.1 0.1 0.6 0.1 30.6 30.3 27.1 31.5 28.4 28.2 34.0 33.5 28.7 24.5 31.8 24.2 3.9 9.6 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.0 0.0 2.5 3.7 0.0 55.5 0.3 0.0 1.9 5.7 0.0 3.4 0.7 2.1 0.0 0.0 0.0 11.8 3.6 1.1 0.0 2.0 1.3 0.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 9.2 2.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 17.4 0.3 0.1 0.0 0.0 MYRFL "bcm1377, C12orf15, C12orf28, FLJ25056" ENSG00000166268 "Myelin regulatory factor like" Q96LU7 12 69825227-69959097 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "intestine: 23.0" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 102.3;Late spermatids: 30.4;Oligodendrocyte precursor cells: 70.4;Proximal enterocytes: 30.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 5.2;SK-BR-3: 2.6;T-47d: 11.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA049340 Approved Approved Nucleoli "Intracellular and membrane" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli "HPA049340: AB_2680719" "unprognostic (2.95e-2)" "unprognostic (6.25e-2)" "unprognostic (2.49e-2)" "unprognostic (1.42e-1)" "unprognostic (5.18e-2)" "unprognostic (2.34e-1)" "unprognostic (5.45e-2)" "unprognostic (6.50e-2)" "unprognostic (3.37e-1)" "unprognostic (2.65e-1)" "unprognostic (3.08e-1)" "unprognostic (8.99e-2)" "unprognostic (1.91e-2)" "unprognostic (3.89e-2)" "unprognostic (2.07e-2)" "unprognostic (1.17e-1)" "unprognostic (9.96e-2)" 0.3 0.4 1.3 0.0 1.2 0.0 0.5 3.1 1.7 0.1 1.3 0.2 23.0 0.1 0.9 0.1 0.1 0.1 0.4 1.5 1.3 2.0 0.3 0.2 0.2 2.1 1.1 0.0 0.7 0.0 0.9 0.2 2.1 0.7 0.1 0.5 0.6 0.4 0.0 1.4 21.2 0.1 0.9 0.1 0.1 2.5 1.5 0.2 0.2 0.0 0.4 0.0 0.1 1.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 5.2 0.1 0.0 0.0 0.0 0.9 0.8 0.0 0.2 0.1 0.0 2.6 0.0 0.9 11.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 3.1 1.7 1.5 1.3 2.1 1.1 2.1 0.9 1.5 1.4 0.0 0.0 0.0 3.6 0.0 0.1 0.1 0.0 0.0 0.7 0.7 0.1 1.5 0.0 0.3 5.5 0.0 0.2 0.0 0.3 3.9 0.7 13.9 0.4 0.0 0.0 0.0 0.4 9.4 0.0 0.0 0.4 1.1 0.7 0.0 0.1 0.0 0.0 0.1 0.0 102.3 3.2 0.0 0.0 0.0 30.4 0.9 0.1 0.0 1.0 0.0 0.2 0.0 70.4 10.8 0.4 4.8 0.4 0.0 0.1 30.8 0.8 0.7 0.2 0.0 0.5 0.2 1.0 0.6 0.0 1.1 0.0 0.1 0.1 4.7 0.0 MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.8;lymphoid tissue: 272.2" "Cell type enriched" "Detected in many" 6 "Plasma cells: 4000.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 160.4;plasmacytoid DC: 569.3" "Group enriched" "Detected in many" 116 "B-cells: 160.4;dendritic cells: 569.3" "Group enriched" "Detected in some" 5 "Karpas-707: 581.5;RPMI-8226: 2193.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 350000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043745: AB_10960359, HPA052694: AB_2681919" "unprognostic (4.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.27e-4)" "unprognostic (2.21e-2)" "prognostic favorable (4.60e-5)" "unprognostic (6.57e-2)" "unprognostic (1.35e-1)" "unprognostic (6.45e-3)" "unprognostic (7.10e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.15e-8)" "unprognostic (7.22e-2)" "unprognostic (3.14e-1)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" 4.4 9.1 0.0 87.4 0.1 33.0 21.0 0.0 0.7 18.3 0.2 70.1 89.8 1.8 0.4 10.1 5.7 14.3 2.3 0.0 0.0 5.9 5.8 15.9 123.2 0.1 0.0 4.9 1.3 0.0 0.7 0.0 0.1 5.1 39.9 0.0 56.7 4.9 0.1 0.4 47.8 2.1 0.4 272.2 66.6 2.4 0.1 147.3 9.1 0.0 117.8 58.7 3.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 256.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 144.6 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 128.5 0.5 581.5 0.0 0.0 227.8 2.2 0.0 0.0 0.0 90.1 0.3 2193.9 0.0 0.0 0.3 0.8 0.0 11.4 0.0 0.0 3.1 0.1 0.6 0.0 1.8 0.1 0.0 262.0 16.7 223.0 0.1 0.4 0.0 0.0 0.1 0.1 1.5 0.1 3.0 160.4 0.6 1.1 0.5 75.6 0.1 0.2 3.1 2.7 0.0 569.3 0.2 26.1 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.3 0.4 6.4 10.1 0.0 665.7 2.5 1.3 0.1 0.0 0.0 3.7 3.2 1.1 4.3 2.0 0.0 0.0 0.1 235.0 0.9 0.0 0.1 0.1 1.8 0.4 2.0 1.2 49.3 0.0 0.0 0.1 2.0 6.1 0.4 2.5 0.1 11.4 14.0 0.1 0.0 0.0 1.1 0.0 7.1 3.4 1.1 0.0 4.7 540.7 0.0 1.0 0.0 4.1 0.0 0.0 0.1 0.4 0.0 4000.1 3.0 1.2 1.9 1.2 0.0 0.0 1.7 2.1 0.1 0.1 0.4 2.4 2.2 100.7 0.5 9.7 0.4 N4BP1 ENSG00000102921 "NEDD4 binding protein 1" O75113 16 48538726-48620148 "Predicted intracellular proteins" "Immunity, Innate immunity" "Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 134.6;Glandular and luminal cells: 113.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 8.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040849, HPA041080" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA040849: AB_10794866, HPA041080: AB_10794186" "unprognostic (1.07e-1)" "unprognostic (2.17e-1)" "unprognostic (5.07e-2)" "unprognostic (2.50e-3)" "unprognostic (1.16e-1)" "unprognostic (3.19e-1)" "unprognostic (4.35e-3)" "unprognostic (9.18e-2)" "unprognostic (4.36e-1)" "unprognostic (1.10e-1)" "unprognostic (3.71e-1)" "unprognostic (1.35e-1)" "prognostic favorable (9.03e-8)" "unprognostic (9.00e-2)" "unprognostic (1.49e-1)" "unprognostic (1.96e-1)" "unprognostic (8.36e-2)" 9.3 6.7 8.0 7.3 7.8 10.3 9.0 9.7 8.0 10.2 7.9 8.8 5.9 8.6 8.3 18.9 8.4 6.3 7.9 7.6 11.0 7.4 7.0 14.7 7.5 8.5 7.8 9.7 7.6 11.4 9.1 7.5 8.2 8.8 6.3 6.9 10.7 6.4 10.5 19.9 9.3 6.3 7.1 10.9 9.2 4.7 10.7 10.3 8.3 7.9 9.0 8.1 11.3 8.4 7.1 11.8 8.3 8.5 11.4 9.0 6.9 6.5 9.9 12.4 6.3 9.3 5.8 7.9 5.9 10.0 5.5 14.4 7.5 10.3 6.8 4.9 6.2 4.1 4.7 8.3 11.1 6.2 10.8 13.0 15.5 4.4 6.4 9.1 6.3 8.1 6.4 8.2 7.5 4.0 7.4 11.2 6.6 7.3 6.7 11.1 13.5 12.4 6.2 11.9 9.3 6.6 5.5 10.0 9.2 8.6 4.2 8.5 9.3 6.3 5.6 3.5 3.9 12.2 7.8 12.0 7.3 4.9 5.6 0.9 1.3 1.8 1.0 1.2 1.3 0.9 1.3 1.6 0.8 0.6 1.1 1.1 8.4 0.4 0.9 1.0 1.0 0.6 8.0 7.8 9.7 8.0 7.6 11.0 8.5 7.8 8.2 7.1 10.7 8.4 41.2 134.6 32.7 28.4 15.3 20.0 21.6 32.4 19.4 24.1 21.3 21.2 15.1 22.8 25.8 7.3 16.7 13.4 53.8 35.4 5.9 8.4 6.4 36.8 35.8 25.7 9.6 6.5 47.5 13.2 10.5 20.1 30.5 113.8 12.6 23.1 24.3 13.4 19.5 26.9 50.1 21.2 6.1 25.9 40.3 3.7 16.1 36.5 5.4 58.1 31.9 15.3 21.6 38.7 54.8 26.7 21.6 20.7 30.2 30.6 16.1 9.4 18.4 23.0 0.0 26.3 17.6 12.6 24.4 26.8 22.7 28.5 36.5 23.8 13.4 47.5 N4BP2L2 "CG005, PFAAP5" ENSG00000244754 "NEDD4 binding protein 2 like 2" Q92802 13 32432417-32538885 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039338, HPA039434, HPA059327" Approved Approved Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 52: Non-specific - Ribosome" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA039338: AB_2676453, HPA039434: AB_10673143, HPA059327: AB_2683981" "unprognostic (1.13e-1)" "unprognostic (1.72e-1)" "unprognostic (3.15e-1)" "unprognostic (5.81e-2)" "unprognostic (6.83e-2)" "unprognostic (6.51e-2)" "unprognostic (8.95e-2)" "unprognostic (6.29e-3)" "unprognostic (6.04e-2)" "unprognostic (1.87e-1)" "unprognostic (2.71e-3)" "unprognostic (2.67e-2)" "unprognostic (4.73e-3)" "unprognostic (1.49e-1)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (4.03e-3)" 29.0 28.4 29.7 19.9 33.1 26.4 40.9 39.3 36.3 28.7 25.8 26.0 17.9 39.1 37.8 23.3 27.3 29.0 42.7 26.6 29.2 30.8 36.8 34.9 28.4 28.3 28.4 47.5 18.1 33.7 23.0 23.4 29.4 36.1 28.2 38.0 24.0 30.3 65.3 29.2 24.9 31.6 30.0 31.7 26.1 20.0 27.9 33.0 36.6 60.8 25.0 31.5 19.8 37.0 18.1 13.7 35.0 25.4 31.6 39.1 29.7 34.0 31.8 28.3 25.7 24.1 44.7 19.4 18.2 37.4 44.7 30.2 36.1 32.6 37.7 46.7 17.9 35.6 30.9 29.4 50.1 46.0 20.3 42.4 42.4 26.1 31.2 47.7 43.9 34.4 28.6 18.2 39.8 24.1 36.1 44.5 31.4 79.2 15.6 29.7 32.0 21.5 36.2 24.9 12.8 32.1 22.2 25.0 48.4 39.9 27.6 64.7 33.5 15.4 17.1 17.1 16.4 17.3 19.6 16.4 21.2 30.5 25.7 35.4 13.7 29.3 17.1 16.4 23.7 18.1 20.3 18.0 13.0 16.1 23.4 20.1 20.3 21.2 23.0 16.6 20.1 12.2 29.7 33.1 39.3 36.3 26.6 29.2 28.3 28.4 29.4 30.0 27.9 37.0 269.4 173.1 174.2 321.3 275.3 137.9 319.5 236.5 166.8 222.0 167.1 144.8 186.6 138.7 180.1 217.0 248.1 182.4 311.3 208.5 92.0 132.9 132.3 164.3 180.6 199.5 175.8 118.9 354.5 74.7 81.8 189.0 175.8 139.2 212.8 256.3 198.5 134.6 119.1 249.0 386.1 173.0 217.7 161.6 129.6 140.2 370.0 175.9 124.5 244.5 308.4 108.4 382.1 367.4 586.4 116.7 282.3 301.7 187.9 253.3 338.7 92.3 175.1 335.8 315.5 234.5 197.3 187.6 89.8 89.3 137.7 191.5 292.6 180.5 122.4 275.1 NAA15 "FLJ13340, NARG1, NATH, TBDN100" ENSG00000164134 "N-alpha-acetyltransferase 15, NatA auxiliary subunit" Q9BXJ9 4 139301505-139420033 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023589, HPA050661" Approved Supported "Nuclear bodies,Cytosol" NA NA 140000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Nuclear bodies" "HPA023589: AB_1854311, HPA050661: AB_2681208" "unprognostic (6.25e-3)" "unprognostic (5.95e-2)" "unprognostic (7.80e-3)" "unprognostic (8.45e-2)" "unprognostic (2.88e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.16e-2)" "unprognostic (9.20e-3)" "unprognostic (1.07e-2)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "unprognostic (8.65e-2)" "unprognostic (7.37e-3)" "unprognostic (2.12e-1)" "unprognostic (8.28e-3)" "unprognostic (1.58e-1)" 9.1 8.9 6.5 11.4 7.3 16.4 9.9 12.4 8.3 7.3 7.3 8.4 7.6 8.9 6.0 12.5 7.1 7.0 10.0 6.5 6.7 7.5 10.9 6.4 14.5 7.3 6.8 7.9 7.8 9.7 5.8 10.6 7.7 8.3 9.1 9.2 6.2 7.2 17.0 9.3 7.0 8.7 6.9 8.5 7.9 13.1 6.9 13.4 9.0 16.3 15.5 14.5 7.7 10.5 44.7 32.1 30.4 49.2 21.7 26.4 37.3 42.2 27.6 39.9 30.6 45.3 38.2 91.1 25.3 35.0 34.6 28.1 80.5 51.7 57.2 42.8 29.6 49.0 29.6 29.8 23.0 90.5 30.5 18.7 31.0 50.4 39.1 21.1 40.5 35.2 92.1 38.7 42.9 35.6 86.8 26.8 50.7 83.4 25.0 53.4 40.9 47.0 31.8 37.2 39.3 30.8 28.2 45.7 28.8 30.6 27.8 35.2 35.0 38.3 27.0 36.7 48.7 46.5 89.0 88.7 32.9 64.6 37.4 4.2 3.4 1.1 5.0 3.9 5.9 4.8 5.3 5.9 4.7 5.3 5.1 5.8 2.6 4.5 3.9 4.0 5.5 2.1 6.5 7.3 12.4 8.3 6.5 6.7 7.3 6.8 7.7 6.9 6.9 10.5 28.4 48.1 33.8 28.4 39.7 93.4 69.6 20.7 29.0 34.0 28.1 15.7 46.9 22.8 32.3 20.2 20.9 39.9 22.8 14.4 15.6 28.1 9.0 40.3 38.9 31.5 15.6 34.5 44.0 19.5 50.8 32.9 21.4 40.5 34.8 35.7 16.8 28.1 32.5 40.4 45.9 20.8 18.3 24.1 35.0 11.3 25.4 27.8 28.4 29.0 26.6 27.7 32.0 42.3 57.6 26.5 16.2 29.0 23.4 53.8 10.2 16.4 34.0 36.3 32.9 69.0 47.4 90.0 59.7 44.0 99.3 41.7 31.7 32.1 32.5 70.2 NAA38 "LSMD1, MGC14151, PFAAP2" ENSG00000183011 "N-alpha-acetyltransferase 38, NatC auxiliary subunit" Q9BRA0 17 7856685-7885238 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1601.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059189 Supported Nucleoplasm "Intracellular and membrane" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA059189: " "unprognostic (6.84e-2)" "unprognostic (1.65e-3)" "unprognostic (1.30e-2)" "unprognostic (1.85e-3)" "unprognostic (2.76e-2)" "unprognostic (3.35e-1)" "unprognostic (4.72e-2)" "unprognostic (1.05e-1)" "unprognostic (2.27e-1)" "unprognostic (7.28e-3)" "unprognostic (1.48e-3)" "unprognostic (3.31e-1)" "unprognostic (5.83e-3)" "unprognostic (1.58e-1)" "unprognostic (6.02e-2)" "unprognostic (2.66e-1)" "unprognostic (9.75e-2)" 72.1 102.2 137.4 33.3 142.4 76.0 67.3 143.6 188.0 58.3 135.3 77.4 30.8 54.9 30.9 65.8 57.4 29.1 99.7 139.4 139.3 87.6 67.8 50.7 45.7 137.7 137.3 45.3 60.1 76.6 73.0 22.6 137.9 71.5 27.0 29.4 56.2 31.8 130.4 59.5 49.2 24.5 138.1 72.6 65.9 97.8 142.5 45.2 60.1 93.4 31.4 60.0 55.5 142.0 131.4 234.9 129.4 132.9 70.8 78.3 44.8 59.7 68.4 108.3 89.9 89.0 54.6 89.6 98.5 63.6 69.2 105.4 69.8 110.3 26.8 134.1 318.2 137.3 279.7 131.0 68.4 38.6 101.9 114.3 60.4 71.0 46.3 74.5 105.9 201.9 29.1 95.3 63.6 157.3 140.0 91.6 29.2 98.9 271.5 142.0 59.6 59.4 101.0 72.6 57.6 110.5 46.6 111.1 87.3 18.7 68.8 100.0 57.6 72.2 52.0 59.0 170.8 39.1 43.8 34.8 121.5 159.1 72.2 313.1 275.2 196.9 176.1 244.0 163.4 273.8 186.3 181.9 332.4 234.2 167.1 173.6 201.1 152.9 239.8 304.0 215.3 299.0 137.4 142.4 143.6 188.0 139.4 139.3 137.7 137.3 137.9 138.1 142.5 142.0 263.1 76.9 140.5 16.3 117.8 94.1 85.8 171.8 144.5 98.5 218.1 305.4 344.3 128.7 107.7 253.8 50.1 160.2 107.4 227.2 518.5 100.6 646.3 189.4 104.9 183.6 226.6 201.2 18.3 158.4 128.0 102.6 80.5 133.1 100.1 131.1 213.5 381.3 210.5 40.4 21.7 211.2 146.5 222.8 96.8 1601.4 116.8 149.9 76.5 14.0 195.2 221.6 182.3 34.7 13.3 134.0 161.6 113.2 161.7 86.8 184.1 468.0 107.1 126.5 111.7 70.2 109.8 120.5 132.4 182.1 99.4 91.9 103.5 175.3 289.5 129.3 NAAA ASAHL ENSG00000138744 "N-acylethanolamine acid amidase" Q02083 4 75913660-75941013 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 142.2;Kupffer cells: 115.8;Langerhans cells: 109.9;Proximal enterocytes: 167.7" "Cancer enriched" "Detected in all" 4 "prostate cancer: 31.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 672.4;non-classical monocyte: 583.3" "Lineage enriched" "Detected in all" 5 "monocytes: 672.4" "Cell line enhanced" "Detected in many" "U-2197: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026135 Approved "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "CAB026135: " "unprognostic (5.30e-3)" "unprognostic (1.23e-2)" "unprognostic (1.41e-2)" "prognostic favorable (1.93e-4)" "unprognostic (1.10e-1)" "unprognostic (2.17e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-2)" "unprognostic (2.24e-1)" "unprognostic (2.87e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.63e-1)" "unprognostic (2.15e-2)" "unprognostic (2.54e-1)" "unprognostic (3.20e-2)" "unprognostic (3.42e-3)" "unprognostic (6.21e-2)" 19.0 14.6 9.2 30.0 10.0 18.5 37.4 10.9 10.8 23.0 14.1 61.8 30.9 12.9 9.1 28.4 16.4 15.7 19.9 9.5 13.3 40.6 68.4 23.0 48.4 11.2 11.1 8.2 7.6 11.7 7.7 19.4 11.7 70.9 69.9 32.7 31.5 11.4 8.6 22.8 60.7 15.4 9.5 63.8 18.5 3.4 13.2 16.3 15.9 13.0 27.9 20.0 18.4 14.5 11.9 26.6 1.1 0.7 62.4 62.8 1.1 17.5 11.6 11.8 4.0 9.3 41.1 1.0 8.9 43.5 0.4 23.1 34.8 13.4 7.1 17.0 1.3 8.4 19.4 22.6 14.3 31.4 29.6 16.0 10.0 10.3 3.5 18.4 19.1 18.7 9.6 35.9 10.6 43.5 20.2 20.5 13.5 53.4 10.5 13.5 0.4 55.6 12.4 6.7 15.9 2.3 18.1 56.2 5.4 1.8 63.3 54.1 28.8 0.7 1.5 78.6 0.8 8.8 3.8 5.9 14.8 44.5 7.4 48.6 270.1 110.3 62.0 672.4 67.5 58.8 78.4 61.8 143.2 40.4 65.2 54.5 90.3 35.5 583.3 53.2 114.6 233.7 9.2 10.0 10.9 10.8 9.5 13.3 11.2 11.1 11.7 9.5 13.2 14.5 10.6 0.0 7.3 7.2 31.2 11.3 18.8 5.7 4.0 11.5 31.3 14.2 4.4 25.8 10.9 5.5 18.8 24.6 19.5 142.2 13.7 5.7 0.5 12.1 18.1 14.6 48.0 10.8 17.7 8.4 19.2 28.2 3.1 11.9 15.2 3.5 18.5 37.2 39.7 11.8 27.4 45.4 8.2 115.8 109.9 0.0 10.5 80.3 17.8 7.5 77.8 7.7 16.5 5.0 4.8 4.1 46.7 7.5 16.8 55.4 167.7 12.4 27.7 86.9 0.0 31.8 16.7 1.1 0.9 15.9 18.9 13.3 34.8 9.1 24.4 14.0 NAGA D22S674 ENSG00000198951 Alpha-N-acetylgalactosaminidase P17050 22 42058334-42070842 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 65.0;Hofbauer cells: 91.6;Kupffer cells: 64.4;monocytes: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 202.5;intermediate monocyte: 249.1;myeloid DC: 195.2;non-classical monocyte: 257.9;plasmacytoid DC: 119.8" "Group enriched" "Detected in all" 6 "dendritic cells: 195.2;monocytes: 257.9" "Cell line enhanced" "Detected in all" "HMC-1: 190.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000649 Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA000649: AB_1079448" "unprognostic (3.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.45e-3)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (3.02e-2)" "unprognostic (4.27e-1)" "unprognostic (1.32e-2)" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.93e-1)" "unprognostic (3.64e-2)" "unprognostic (3.68e-2)" "unprognostic (1.92e-3)" "unprognostic (8.95e-2)" "unprognostic (2.53e-1)" 21.4 12.7 9.3 32.3 10.4 20.1 13.4 10.3 10.1 20.6 17.0 26.1 20.4 17.2 12.4 17.2 20.0 22.1 16.0 8.9 11.5 14.9 31.9 27.1 20.8 13.9 10.8 17.0 11.4 39.2 11.7 42.8 12.6 18.2 26.7 7.7 17.3 18.6 7.7 13.4 24.2 28.3 12.2 20.3 16.6 9.0 12.0 13.9 15.1 12.3 19.0 24.8 13.7 14.4 27.8 14.0 21.7 38.9 37.0 41.9 15.9 22.4 45.7 37.9 39.2 31.4 39.9 13.5 13.5 49.1 22.9 19.2 16.7 27.4 22.3 31.0 21.2 33.5 20.1 21.5 21.5 28.1 190.4 28.9 23.8 34.0 14.4 19.5 63.4 11.6 12.4 56.0 30.2 32.3 10.4 11.5 5.8 25.3 18.5 23.0 11.0 24.2 29.4 32.7 6.7 7.7 29.8 27.0 29.3 19.1 40.4 50.9 34.4 26.6 31.8 17.1 20.7 30.9 33.3 10.9 28.3 52.7 33.4 36.5 202.5 25.1 13.6 249.1 13.8 10.5 14.1 12.7 195.2 6.9 9.2 8.4 9.9 18.8 257.9 119.8 18.3 121.0 9.3 10.4 10.3 10.1 8.9 11.5 13.9 10.8 12.6 12.2 12.0 14.4 6.5 9.6 6.7 4.6 8.2 3.3 9.4 10.9 5.7 2.8 6.7 6.2 4.2 4.3 11.3 7.3 8.4 46.1 11.0 27.3 3.9 15.4 15.8 5.6 8.8 11.2 6.0 12.4 1.1 8.1 65.0 13.8 6.1 10.2 9.5 3.2 9.3 33.6 91.6 0.0 2.0 15.0 6.1 64.4 36.3 17.9 7.2 52.5 19.6 12.2 65.8 5.9 6.2 0.5 2.0 13.0 23.9 6.8 22.2 6.0 40.0 9.8 15.7 6.4 19.7 6.1 10.0 10.7 5.2 7.1 3.4 58.3 6.9 6.5 15.4 10.0 NAGLU NAG ENSG00000108784 N-acetyl-alpha-glucosaminidase P54802 17 42536241-42544449 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Charcot-Marie-Tooth disease, Disease variant, Mucopolysaccharidosis, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038815 Supported "Intracellular and membrane" NA NA 270000000 "Cluster 37: B-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA038815: AB_10697398" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (6.48e-2)" "prognostic favorable (4.17e-4)" "prognostic unfavorable (6.59e-4)" "unprognostic (1.46e-1)" "unprognostic (1.75e-3)" "unprognostic (3.09e-2)" "unprognostic (2.20e-1)" "unprognostic (6.68e-2)" "prognostic favorable (6.90e-4)" "unprognostic (8.07e-2)" "prognostic favorable (2.58e-6)" "unprognostic (2.25e-1)" "unprognostic (8.74e-3)" "unprognostic (2.15e-2)" "unprognostic (1.62e-1)" 41.6 37.9 12.5 14.8 21.6 20.3 35.3 16.6 16.7 31.1 28.7 25.1 24.3 34.7 12.8 19.5 27.6 27.4 20.1 12.0 15.0 39.3 59.3 30.8 24.0 18.0 19.2 35.2 63.8 21.3 22.5 26.1 20.1 28.3 16.4 3.1 37.7 18.4 16.0 25.1 30.9 13.8 14.2 40.7 35.1 8.7 19.5 17.1 37.6 9.7 13.4 28.9 23.9 30.0 16.0 55.3 10.8 24.6 106.6 34.5 36.4 24.0 56.9 24.9 31.7 14.9 40.4 20.3 23.7 37.4 54.7 38.3 9.7 11.7 5.5 15.8 20.2 11.2 31.3 31.8 35.3 13.3 27.7 41.4 17.8 13.6 16.9 27.3 32.8 3.6 16.6 39.3 27.9 38.9 2.2 23.0 12.6 34.6 7.0 8.7 23.6 47.2 33.1 36.1 16.2 24.4 12.9 17.6 20.4 15.6 82.1 14.1 25.8 59.3 9.7 23.8 15.7 52.6 25.8 17.6 35.9 14.4 43.1 1.1 2.4 1.9 2.5 1.8 2.4 2.4 1.0 1.3 2.1 1.8 1.8 1.4 1.1 2.1 2.9 2.8 0.2 1.1 12.5 21.6 16.6 16.7 12.0 15.0 18.0 19.2 20.1 14.2 19.5 30.0 14.1 12.8 7.8 17.3 9.0 2.8 6.1 3.9 2.2 15.5 14.2 8.9 3.8 18.6 4.9 18.4 4.2 23.8 11.4 21.1 3.9 18.4 0.3 5.8 14.5 12.2 6.7 4.4 2.3 33.2 14.5 26.4 27.0 12.1 2.5 40.1 24.3 43.7 37.6 15.2 3.1 17.6 0.0 26.0 3.5 2.4 19.9 19.0 16.0 10.3 5.9 13.2 8.2 6.0 19.2 15.8 5.4 12.8 12.9 10.7 23.0 31.8 3.7 6.7 6.6 18.0 12.8 0.4 6.0 6.1 3.4 18.5 6.0 74.6 15.0 6.0 NAGS "AGAS, ARGA, NAT7" ENSG00000161653 "N-acetylglutamate synthase" Q8N159 17 44004622-44009068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Urea cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 15.9;liver: 48.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 21.7;Proximal enterocytes: 44.2;Proximal tubular cells: 20.7;Spermatocytes: 16.0" "Cancer enhanced" "Detected in all" "liver cancer: 12.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.5;HHSteC: 5.2;TIME: 7.1;U-87 MG: 10.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA027300 Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA027300: AB_2672207" "unprognostic (1.51e-3)" "unprognostic (9.24e-2)" "unprognostic (1.68e-1)" "unprognostic (8.67e-2)" "unprognostic (1.44e-2)" "unprognostic (1.30e-3)" "unprognostic (2.38e-2)" "unprognostic (1.98e-1)" "unprognostic (3.14e-2)" "unprognostic (2.73e-2)" "unprognostic (2.53e-3)" "unprognostic (1.46e-1)" "unprognostic (5.19e-2)" "unprognostic (6.99e-2)" "unprognostic (1.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" 0.9 0.7 2.0 0.5 1.2 0.0 1.4 0.9 2.0 0.8 0.0 2.4 15.9 0.8 1.8 1.4 0.7 0.4 1.2 1.0 3.5 4.9 48.2 1.9 0.3 2.0 1.4 0.6 0.3 3.3 0.5 0.1 2.2 1.1 0.5 0.0 1.0 1.4 0.2 1.0 13.6 0.1 1.3 0.4 0.4 0.6 3.6 0.1 4.4 0.2 0.1 0.4 1.0 1.0 2.9 0.1 0.0 0.4 0.0 5.5 0.1 0.5 0.1 0.1 0.2 1.7 0.7 0.0 1.1 0.0 0.1 1.3 0.1 1.5 0.3 0.2 0.7 0.1 0.2 2.2 5.2 0.0 0.0 3.2 0.0 0.7 0.0 0.6 1.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 1.5 2.7 0.0 0.3 0.0 0.1 0.0 2.1 0.0 0.9 0.0 0.0 0.2 0.2 0.0 7.1 2.5 0.7 0.2 0.6 0.1 0.1 0.1 10.0 0.0 0.3 0.8 0.5 0.7 0.9 0.4 0.7 0.3 0.6 0.8 0.5 0.3 0.3 0.4 0.3 0.2 0.8 0.1 0.5 0.3 2.0 1.2 0.9 2.0 1.0 3.5 2.0 1.4 2.2 1.3 3.6 1.0 1.8 3.2 4.2 0.0 0.9 1.5 0.9 1.9 6.8 0.4 3.5 4.8 2.6 2.8 2.9 12.9 0.0 0.9 1.1 10.5 7.9 1.9 5.8 0.5 0.2 2.3 7.2 0.0 0.0 4.2 1.9 0.9 2.0 0.2 0.0 0.3 0.7 21.7 1.1 0.0 0.3 3.8 4.1 1.9 5.3 5.3 1.5 2.1 0.0 1.0 6.1 1.0 3.1 0.0 0.0 5.1 11.1 0.7 0.0 0.6 44.2 20.7 1.1 0.5 0.0 0.2 0.9 16.0 2.5 1.0 0.9 0.4 1.4 0.7 6.6 0.6 NAPSA "KAP, Kdap, NAP1, NAPA" ENSG00000131400 "Napsin A aspartic peptidase" O96009 19 50358477-50365830 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lung: 1075.5" "Cell type enriched" "Detected in many" 5 "Alveolar cells type 2: 3072.3" "Cancer enriched" "Detected in many" 18 "lung cancer: 249.9" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 8.7" "Group enriched" "Detected in many" 7 "B-cells: 4.3;dendritic cells: 8.7" "Cell line enriched" "Detected in some" 31 "U-698: 42.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB009591, HPA045280, HPA047236, HPA047744" Enhanced "Secreted in other tissues" NA NA 1500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 19: Lung - Lung function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB009591: , HPA045280: AB_2679283, HPA047236: AB_2679993, HPA047744: AB_2680143" "unprognostic (5.36e-2)" "unprognostic (4.77e-2)" "unprognostic (1.64e-3)" "unprognostic (1.78e-1)" "unprognostic (1.93e-1)" "unprognostic (4.65e-2)" "unprognostic (1.02e-1)" "unprognostic (8.30e-3)" "unprognostic (2.29e-1)" "unprognostic (2.23e-2)" "unprognostic (1.76e-3)" "unprognostic (7.67e-3)" "prognostic favorable (1.21e-4)" "unprognostic (4.08e-4)" "unprognostic (3.29e-1)" "unprognostic (9.83e-3)" "unprognostic (7.26e-5)" 0.4 0.9 0.8 1.6 0.9 0.1 0.5 0.9 0.9 0.7 0.7 0.6 0.4 0.5 2.0 0.4 1.0 0.1 0.4 0.8 0.9 106.3 1.2 1075.5 1.2 0.9 0.8 2.1 1.0 0.2 0.6 0.4 0.9 1.0 0.4 0.4 0.6 1.0 0.2 1.1 1.5 0.1 0.8 1.1 0.9 1.8 1.0 0.4 1.7 0.0 0.5 0.4 0.7 1.1 0.2 0.4 0.0 0.2 0.2 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.3 0.2 0.0 0.5 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.4 1.3 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.7 0.2 0.5 0.2 0.3 0.4 0.6 0.0 0.2 1.1 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.4 0.2 0.0 0.1 1.0 0.0 0.2 0.4 42.1 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.9 0.0 4.3 0.2 0.3 2.6 1.7 0.4 0.4 0.5 0.4 0.7 8.7 0.0 1.1 0.8 0.9 0.9 0.9 0.8 0.9 0.9 0.8 0.9 0.8 1.0 1.1 0.3 522.4 3072.3 0.3 3.8 0.1 0.5 0.2 0.0 1.3 0.8 0.9 0.4 1.5 45.9 46.0 4.2 0.5 0.4 0.8 9.8 0.6 47.2 12.6 0.4 6.2 0.0 0.4 0.5 0.8 0.3 5.8 0.5 1.5 69.4 1.0 0.4 0.4 0.3 0.0 0.5 1.0 0.0 1.6 5.3 9.1 0.9 7.9 0.0 1.9 0.2 1.5 1.0 0.0 1.4 0.1 2.3 0.4 0.6 0.4 2.0 276.1 16.4 0.9 0.0 0.3 0.3 1.4 1.4 0.0 0.6 0.1 12.9 0.4 0.9 0.1 NAT14 KLP1 ENSG00000090971 "N-acetyltransferase 14 (putative)" Q8WUY8 19 55485188-55487568 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.6;Horizontal cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HEK 293: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047187 Approved Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA047187: AB_2679974" "unprognostic (5.96e-2)" "unprognostic (1.10e-1)" "unprognostic (2.92e-2)" "unprognostic (5.43e-2)" "unprognostic (1.32e-1)" "unprognostic (3.59e-2)" "unprognostic (1.69e-2)" "unprognostic (7.01e-2)" "unprognostic (1.94e-1)" "unprognostic (2.97e-1)" "unprognostic (9.12e-2)" "unprognostic (6.41e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (7.00e-2)" "unprognostic (6.74e-2)" "unprognostic (9.85e-2)" "unprognostic (1.58e-1)" 5.3 13.1 32.9 4.5 32.2 3.9 7.5 32.2 37.8 23.5 30.2 20.5 2.4 23.8 7.8 5.2 25.2 4.0 11.6 33.8 32.5 25.5 6.5 10.5 3.8 29.8 32.9 20.6 8.4 10.7 47.1 6.9 28.7 14.9 2.1 8.4 5.3 7.8 3.0 5.7 8.5 8.8 27.8 7.1 10.1 11.6 36.2 53.6 20.0 1.2 2.9 11.8 10.8 29.0 8.2 27.6 32.1 59.8 12.9 16.3 19.4 29.6 35.5 32.5 46.3 9.7 26.6 3.1 10.3 19.5 16.4 10.6 20.8 18.8 20.0 32.9 168.2 26.1 41.0 21.9 23.3 19.4 25.8 22.7 6.5 22.7 6.2 65.5 24.3 46.9 32.3 9.1 19.7 10.0 33.1 29.7 44.2 16.4 13.1 32.7 19.9 12.6 78.2 15.3 93.4 64.5 11.9 17.8 28.9 12.2 14.5 20.0 28.5 11.8 31.5 1.7 24.5 18.0 7.4 13.7 26.7 3.3 30.5 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.4 0.1 0.0 0.4 0.0 0.1 32.9 32.2 32.2 37.8 33.8 32.5 29.8 32.9 28.7 27.8 36.2 29.0 4.0 6.4 3.2 9.1 3.8 2.9 6.7 4.4 4.6 62.6 11.7 13.8 4.1 5.7 2.6 29.5 35.5 13.3 3.8 1.2 15.6 14.5 1.5 41.7 31.7 7.2 12.7 10.3 12.9 1.1 8.3 10.4 3.1 9.7 0.0 11.5 3.9 3.6 2.9 148.0 13.1 2.1 4.1 0.8 2.4 3.1 11.8 1.7 5.4 2.8 2.3 39.6 1.0 7.1 2.8 4.3 0.4 10.5 2.7 4.4 0.7 3.7 18.1 39.9 0.0 13.8 12.1 4.2 3.9 0.7 0.6 6.0 2.6 9.7 1.1 1.9 NAV1 "DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1" ENSG00000134369 "Neuron navigator 1" Q8NEY1 1 201622885-201826969 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 169.1;Inhibitory neurons: 161.7;Oligodendrocyte precursor cells: 713.8;Oligodendrocytes: 224.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.4;myeloid DC: 2.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2.1;granulocytes: 3.4" "Cell line enhanced" "Detected in many" "TIME: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012302, HPA018127, HPA027887" Enhanced Approved Microtubules NA NA "Cluster 46: Basophils - DNA binding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Microtubules "CAB012302: AB_776716, HPA018127: AB_1854317, HPA027887: AB_10601040" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (4.12e-2)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-1)" "unprognostic (1.79e-1)" "unprognostic (3.45e-1)" "unprognostic (9.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.68e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (3.45e-2)" "unprognostic (2.16e-1)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" 19.6 2.7 17.4 8.2 18.3 1.6 15.2 8.0 17.7 11.7 0.0 12.3 3.7 10.1 4.3 8.6 7.2 7.5 26.6 17.5 20.3 4.6 1.9 11.1 4.1 24.6 17.9 3.7 4.4 5.2 5.2 11.8 15.1 7.5 5.4 5.4 7.8 6.7 4.8 7.7 6.2 10.3 9.9 3.6 5.3 4.4 21.8 2.8 9.4 6.7 3.7 14.9 12.6 32.5 1.6 2.9 29.0 3.8 84.3 69.5 51.7 44.6 43.0 35.5 30.9 0.0 15.7 0.6 0.7 61.4 19.4 21.5 22.0 14.9 28.4 2.5 3.2 1.4 5.6 0.0 22.5 0.2 19.1 30.6 5.4 62.4 36.0 94.9 80.7 1.8 0.8 2.6 29.8 0.4 0.0 0.1 42.4 0.7 1.7 3.9 65.0 9.3 4.8 4.3 21.9 4.5 11.1 47.6 14.5 19.2 0.4 1.2 187.8 54.5 11.1 54.7 39.4 8.1 2.3 0.2 59.2 5.9 47.5 3.4 0.5 0.1 0.2 0.3 0.1 0.3 0.2 0.0 2.1 0.3 0.2 0.1 0.0 0.1 0.3 0.5 0.0 0.3 17.4 18.3 8.0 17.7 17.5 20.3 24.6 17.9 15.1 9.9 21.8 32.5 77.4 3.2 1.5 169.1 3.1 11.0 2.2 5.9 8.0 34.6 4.8 4.3 29.2 1.5 4.8 12.9 0.0 14.9 0.9 4.7 0.0 13.0 3.6 1.6 6.4 39.3 52.8 1.7 98.2 8.3 54.1 45.8 8.2 4.4 17.7 54.5 21.0 0.7 14.5 25.2 161.7 3.4 6.1 18.3 15.8 3.8 10.8 15.1 23.2 69.3 60.6 11.8 1.0 713.8 224.6 21.7 4.2 0.7 4.9 2.3 0.9 0.6 3.5 4.0 6.6 119.3 18.8 0.6 2.6 16.9 7.0 15.7 2.0 6.6 5.0 3.2 NAXE "AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1" ENSG00000163382 "NAD(P)HX epimerase" Q8NCW5 1 156591756-156609507 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Lipid transport, Transport" Isomerase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 136.7;Distal tubular cells: 201.5;Ductal cells: 112.8;Exocrine glandular cells: 100.1;Proximal tubular cells: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043766, HPA048164" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA043766: AB_2678660, HPA048164: AB_2680294" "unprognostic (1.27e-1)" "unprognostic (2.34e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.38e-2)" "unprognostic (5.32e-2)" "unprognostic (2.46e-3)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.08e-3)" "unprognostic (3.23e-2)" "unprognostic (3.14e-2)" "unprognostic (2.15e-2)" "unprognostic (8.05e-2)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-1)" 47.1 74.8 61.0 20.9 63.7 22.2 47.9 66.1 69.6 56.8 71.1 62.9 45.5 68.8 88.7 58.0 59.5 26.5 111.1 60.9 64.3 83.8 86.5 43.6 27.0 62.7 64.8 46.5 69.7 104.7 70.0 23.7 61.8 62.5 41.6 17.4 53.9 48.3 71.8 55.8 48.3 39.7 64.7 43.2 67.5 40.8 63.5 30.6 59.8 68.2 34.3 55.0 47.8 70.5 114.2 155.4 43.9 84.4 64.0 43.8 55.5 29.5 62.3 69.5 72.6 130.6 76.8 62.4 113.4 52.5 55.9 111.1 49.4 99.0 47.5 81.2 98.5 58.1 76.2 86.1 75.1 60.0 60.9 44.2 123.7 87.9 81.9 53.4 95.4 104.7 54.7 70.1 71.6 209.6 83.3 98.0 43.1 158.1 118.2 87.7 40.2 212.6 93.0 93.6 114.7 102.9 90.4 172.4 141.6 66.4 178.3 117.5 51.1 45.1 64.8 64.6 70.6 180.1 110.3 53.0 63.1 37.0 70.4 25.4 96.3 52.9 121.2 111.3 121.3 236.2 109.4 124.3 89.1 186.5 122.8 114.9 11.4 141.3 89.1 225.7 110.1 186.6 61.0 63.7 66.1 69.6 60.9 64.3 62.7 64.8 61.8 64.7 63.5 70.5 29.5 41.7 32.9 0.0 14.8 0.0 0.0 0.0 0.0 0.0 87.5 96.0 0.0 0.0 23.5 68.0 0.0 136.7 28.7 0.0 201.5 112.8 0.0 27.3 29.9 18.4 0.0 0.0 0.0 100.1 43.1 27.2 0.0 32.0 5.1 53.5 0.0 0.0 92.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 40.8 0.0 0.0 0.0 0.0 91.0 0.0 0.0 6.2 0.0 0.0 219.6 11.7 0.0 0.0 0.0 24.5 0.0 0.0 0.0 0.0 81.3 13.4 48.1 0.0 0.0 NBL1 "D1S1733E, DAN, DAND1, NB, NO3" ENSG00000158747 "NBL1, DAN family BMP antagonist" P41271 1 19596979-19658456 "Predicted intracellular proteins, Predicted secreted proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 676.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.1;Leydig cells: 386.8;Paneth cells: 313.2;Peritubular cells: 356.9;Prostatic glandular cells: 293.3;Proximal enterocytes: 413.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 431.7;HSkMC: 305.6;SK-MEL-30: 473.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007394, CAB026132" Uncertain "Secreted in other tissues" NA NA 8100000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026132: , HPA007394: AB_10601272" "unprognostic (1.65e-1)" "unprognostic (1.65e-2)" "unprognostic (9.03e-2)" "unprognostic (2.85e-1)" "unprognostic (1.33e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (3.92e-1)" "unprognostic (7.88e-2)" "unprognostic (3.10e-2)" "unprognostic (1.92e-2)" "unprognostic (1.39e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.21e-2)" "unprognostic (2.26e-2)" 166.3 27.7 116.1 61.4 115.2 5.7 183.3 90.6 156.0 676.6 125.7 259.3 195.0 253.9 48.3 206.8 281.5 202.6 119.1 147.1 117.1 67.2 5.8 312.0 57.3 101.7 140.7 635.9 27.1 48.3 125.3 21.6 117.0 376.0 109.3 14.5 65.4 113.5 26.6 199.1 314.1 113.0 95.0 25.8 139.9 44.5 109.5 25.3 85.9 28.4 22.4 246.5 373.8 97.3 138.8 42.9 7.2 38.5 431.7 222.7 19.7 195.5 238.6 64.1 64.7 11.8 242.6 0.2 122.2 245.7 44.8 153.4 40.8 180.1 19.6 132.9 23.0 6.8 40.5 72.4 69.4 0.5 3.1 305.6 162.0 94.6 57.6 19.1 48.7 8.0 1.4 0.4 20.6 20.4 0.4 11.7 2.9 142.3 65.2 6.4 0.1 4.7 122.5 16.6 3.1 102.2 31.2 1.2 473.8 7.1 160.2 24.3 68.9 62.4 49.7 180.0 30.3 0.9 1.1 0.8 45.4 0.6 19.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.4 0.0 0.0 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.1 116.1 115.2 90.6 156.0 147.1 117.1 101.7 140.7 117.0 95.0 109.5 97.3 150.4 3.2 2.3 0.0 2.9 174.6 237.3 22.6 107.0 35.5 41.5 32.8 43.5 55.8 11.9 36.8 6.2 1.0 5.1 395.1 3.9 43.0 2.0 15.6 55.7 84.3 54.5 3.4 0.0 7.7 2.6 241.4 39.8 10.1 13.4 80.9 47.8 1.5 54.6 6.7 0.0 244.6 12.2 2.2 76.6 13.1 386.8 6.6 60.5 0.0 5.8 13.4 0.0 0.0 0.0 97.5 313.2 356.9 1.1 293.3 413.8 19.7 24.5 10.2 131.5 14.0 142.9 1.4 7.6 61.4 202.4 1.4 29.6 15.1 220.4 206.5 NBPF26 ENSG00000273136 "NBPF member 26" 1 120723949-120842110 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 54.5;B-cells: 36.4;Basal squamous epithelial cells: 37.0;Erythroid cells: 55.5;Macrophages: 54.4;Squamous epithelial cells: 106.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.3" "Group enriched" "Detected in all" 5 "granulocytes: 13.3;monocytes: 7.3" "Low cell line specificity" "Detected in many" "HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Uncertain Approved Microtubules,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol Microtubules "HPA038748: AB_2676188, HPA038752: , HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (2.42e-1)" "unprognostic (2.11e-1)" "unprognostic (2.24e-1)" "unprognostic (7.64e-3)" "unprognostic (4.21e-1)" "unprognostic (1.34e-3)" "unprognostic (1.69e-1)" "unprognostic (1.26e-2)" "unprognostic (6.31e-5)" "unprognostic (9.78e-3)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" "unprognostic (2.82e-5)" "unprognostic (1.05e-1)" "unprognostic (2.08e-1)" "unprognostic (8.11e-2)" "unprognostic (1.65e-1)" 14.7 7.2 5.4 21.9 5.1 13.2 11.0 7.6 6.3 14.9 13.7 10.2 2.5 15.1 20.1 20.7 11.2 13.3 6.5 3.8 5.8 4.9 10.4 13.3 12.5 5.4 4.4 17.0 8.9 4.3 4.7 8.5 3.6 12.6 9.3 23.1 10.2 8.9 6.4 39.0 8.6 17.3 2.0 13.9 7.5 10.3 8.0 11.9 12.2 5.4 8.5 7.9 11.5 5.8 56.7 0.3 16.4 17.8 18.3 16.9 1.3 19.9 10.1 12.5 12.9 12.2 2.3 4.4 17.2 17.5 21.6 14.4 27.8 28.7 17.4 25.1 1.3 40.1 7.5 4.8 9.1 16.0 11.4 10.2 11.8 31.1 32.6 40.5 0.8 10.5 3.0 30.1 29.5 28.7 4.2 24.6 6.3 2.0 21.5 5.5 15.3 8.2 7.3 19.9 1.5 1.3 22.1 30.5 16.6 19.5 1.0 6.7 17.3 14.0 36.3 43.7 15.7 13.5 4.1 16.2 11.6 23.5 2.2 2.4 5.1 4.6 1.4 2.3 0.7 0.8 1.0 1.2 1.4 2.0 1.0 1.5 13.3 1.3 7.3 1.3 0.5 0.7 5.4 5.1 7.6 6.3 3.8 5.8 5.4 4.4 3.6 2.0 8.0 5.8 0.8 54.5 28.7 3.9 36.4 0.0 2.2 0.0 37.0 0.6 3.9 2.4 2.7 0.0 3.7 0.0 0.0 0.5 4.7 0.6 3.9 4.8 7.6 7.2 4.8 1.4 0.0 55.5 0.4 3.1 2.4 14.9 16.3 7.8 16.4 2.5 1.1 1.4 0.2 0.0 0.3 1.0 0.0 4.4 0.0 0.9 6.5 54.4 0.0 1.0 6.5 0.6 2.1 0.5 0.1 4.0 27.3 4.5 28.0 1.0 1.7 0.7 3.6 2.1 0.0 3.1 6.7 4.9 2.5 106.5 0.0 0.4 21.1 0.9 2.2 0.8 NCAM1 "CD56, NCAM" ENSG00000149294 "Neural cell adhesion molecule 1" P13591 11 112961247-113278436 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 290.1;heart muscle: 145.5" "Cell type enhanced" "Detected in many" "Astrocytes: 530.8;Excitatory neurons: 461.4;Inhibitory neurons: 441.2;Oligodendrocyte precursor cells: 939.0;Oligodendrocytes: 1013.5" "Cancer enriched" "Detected in many" 8 "glioma: 31.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "NK-cell: 53.7" "Lineage enriched" "Detected in many" 15 "NK-cells: 53.7" "Cell line enhanced" "Detected in many" "HEL: 61.3;RH-30: 132.5;SCLC-21H: 107.4;SH-SY5Y: 52.7;U-138 MG: 72.8;WM-115: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000142, CAB018071, HPA039835" Enhanced Enhanced "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 1200000 2300000000 "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Cytosol "CAB000142: , CAB018071: AB_627129, HPA039835: AB_2676705" "unprognostic (7.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.77e-2)" "unprognostic (2.18e-2)" "unprognostic (2.91e-1)" "unprognostic (1.74e-3)" "unprognostic (2.82e-1)" "unprognostic (4.42e-3)" "unprognostic (2.13e-1)" "unprognostic (1.63e-2)" "prognostic favorable (9.11e-6)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (2.97e-2)" "unprognostic (2.24e-1)" "unprognostic (3.75e-2)" "unprognostic (5.82e-5)" 4.6 65.7 124.0 3.9 169.1 1.5 2.7 118.1 140.3 35.1 0.0 47.8 4.6 62.7 3.5 7.0 40.4 4.8 145.5 135.6 179.1 3.2 2.9 1.8 1.3 140.4 134.2 43.8 2.6 0.0 22.2 0.5 147.4 14.9 6.6 117.7 3.6 17.7 31.2 2.1 18.3 46.9 129.7 4.7 23.0 5.0 137.0 0.4 30.2 29.5 1.0 34.8 24.3 290.1 0.1 0.0 20.8 0.3 0.2 0.5 0.3 1.0 0.0 0.7 1.2 0.3 0.3 3.1 18.2 20.1 0.8 0.3 0.1 0.0 0.0 0.4 12.1 61.3 0.1 0.0 2.1 0.0 9.5 12.4 0.1 0.1 18.6 0.1 0.0 0.1 0.0 1.0 20.8 0.0 0.2 5.2 1.8 0.0 0.4 0.1 132.5 10.0 0.0 0.0 107.4 52.7 0.1 0.5 0.1 2.0 0.2 0.8 0.2 72.8 33.4 0.3 31.8 0.1 0.5 0.1 8.3 28.4 79.0 0.0 0.2 0.0 3.6 0.0 1.2 0.0 0.1 0.5 0.1 0.0 0.0 1.4 0.7 53.7 0.0 0.0 0.2 1.9 124.0 169.1 118.1 140.3 135.6 179.1 140.4 134.2 147.4 129.7 137.0 290.1 13.7 0.0 0.0 530.8 0.4 1.7 0.5 0.0 0.0 123.5 5.7 0.6 131.7 0.0 0.0 0.0 37.5 0.6 27.7 0.1 1.9 18.3 6.7 0.3 2.4 2.8 5.4 0.0 461.4 0.0 0.2 12.8 5.1 0.5 1.3 11.7 7.1 0.7 0.4 175.0 441.2 0.0 8.2 4.7 3.8 5.9 15.2 1.8 0.0 35.6 1.2 216.6 59.8 939.0 1013.5 1.3 0.0 10.1 5.6 0.4 0.0 0.2 0.7 98.0 0.0 107.5 4.8 1.0 2.8 0.4 1.7 0.1 13.4 5.6 0.0 0.2 NCAN CSPG3 ENSG00000130287 Neurocan O14594 19 19211958-19252233 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 63 "brain: 73.6" "Cell type enriched" "Detected in some" 6 "Astrocytes: 195.5" "Cancer enriched" "Detected in some" 57 "glioma: 71.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.0;SCLC-21H: 2.3;SH-SY5Y: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036814 Enhanced "Secreted in brain" NA NA 790000 "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA036814: AB_10673666" "unprognostic (1.02e-2)" "unprognostic (2.84e-3)" "unprognostic (1.92e-1)" "unprognostic (1.56e-2)" "unprognostic (2.35e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (1.03e-3)" "unprognostic (1.76e-1)" "unprognostic (2.12e-1)" "unprognostic (4.58e-3)" "unprognostic (4.38e-2)" "unprognostic (9.09e-6)" "unprognostic (1.10e-2)" "unprognostic (2.79e-2)" "unprognostic (2.91e-1)" "unprognostic (2.58e-2)" 0.0 0.1 52.8 0.0 53.1 0.0 0.0 15.2 73.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.6 44.2 0.0 0.0 0.0 0.0 33.3 32.3 0.0 0.0 0.0 0.3 0.0 38.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 21.5 0.0 0.0 0.9 61.5 0.1 0.0 0.0 0.0 0.0 0.0 49.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.8 53.1 15.2 73.6 55.6 44.2 33.3 32.3 38.1 21.5 61.5 49.4 0.0 0.0 0.0 195.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 15.5 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 8.4 0.0 0.5 0.0 29.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.4 0.0 0.1 0.0 0.0 0.3 0.0 0.0 NCBP2AS2 "HIAR, KRASIM, NCBP2-AS2" ENSG00000270170 "NCBP2 antisense 2 (head to head)" Q69YL0 3 196942674-196943543 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 50.3;Cytotrophoblasts: 53.1;dendritic cells: 22.6;Extravillous trophoblasts: 42.3;Hofbauer cells: 43.0;Syncytiotrophoblasts: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.48e-1)" "unprognostic (4.33e-3)" "unprognostic (4.51e-2)" "unprognostic (1.74e-3)" "unprognostic (4.77e-2)" "unprognostic (2.49e-1)" "unprognostic (2.61e-3)" "unprognostic (1.30e-1)" "unprognostic (1.71e-1)" "unprognostic (2.67e-1)" "unprognostic (5.07e-2)" "unprognostic (3.21e-2)" "prognostic favorable (8.92e-4)" "unprognostic (4.19e-2)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (8.66e-3)" 19.0 22.6 32.7 9.7 32.3 38.4 18.8 33.7 33.7 12.6 27.2 31.6 15.9 21.7 13.2 22.5 16.2 6.0 27.9 31.7 34.9 24.9 23.5 14.9 13.9 32.0 31.8 11.5 21.9 20.1 21.4 9.6 33.0 18.7 16.6 13.1 19.8 13.0 45.1 29.5 23.9 10.2 31.2 23.7 23.8 14.0 32.4 18.2 16.9 35.2 10.5 20.7 16.3 32.3 52.7 15.3 26.0 31.3 20.5 18.7 50.0 24.4 16.8 33.2 22.1 29.7 18.7 49.1 87.8 18.3 25.9 41.0 42.8 21.6 26.0 17.5 64.1 39.0 19.3 49.0 23.1 36.4 23.5 30.8 39.4 19.4 24.0 15.1 21.7 45.7 39.7 38.1 14.5 93.9 45.8 65.7 56.9 58.8 74.0 40.7 22.7 60.9 28.0 29.7 59.9 68.0 26.1 39.4 61.3 26.8 80.9 41.4 16.5 15.3 45.4 24.5 52.2 57.1 71.4 119.5 18.0 62.3 20.7 87.4 120.6 116.5 91.6 97.9 99.2 98.3 115.7 106.5 110.0 123.3 141.8 115.3 47.6 127.2 89.7 129.0 118.3 109.7 32.7 32.3 33.7 33.7 31.7 34.9 32.0 31.8 33.0 31.2 32.4 32.3 10.8 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 0.0 0.0 0.0 0.0 53.1 22.6 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 42.3 10.4 0.0 0.0 0.0 0.0 0.0 0.0 43.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 34.3 2.9 0.0 0.0 0.0 NCEH1 "AADACL1, KIAA1363, NCEH" ENSG00000144959 "Neutral cholesterol ester hydrolase 1" Q6PIU2 3 172630249-172711218 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.2;Pancreatic endocrine cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 287.7;LHCN-M2: 133.1;U-251 MG: 132.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026888, HPA043873" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" No No "Cluster 25: Monocytes - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA026888: AB_10601557, HPA043873: " "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (5.74e-2)" "unprognostic (1.27e-1)" "unprognostic (6.88e-3)" "unprognostic (5.41e-2)" "unprognostic (3.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (5.29e-2)" "unprognostic (2.96e-2)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (2.81e-2)" "unprognostic (2.28e-1)" 3.8 16.2 8.7 8.7 15.8 8.3 5.6 2.3 27.5 4.3 0.0 11.6 4.2 4.6 3.2 3.9 3.4 6.9 14.2 12.5 4.3 21.5 4.9 19.9 14.3 9.3 4.9 1.5 4.7 8.0 3.2 6.7 9.6 6.7 12.0 19.6 10.3 4.4 6.1 1.4 4.8 3.4 3.5 11.2 12.8 1.6 7.8 4.9 4.5 7.4 11.2 8.5 2.1 6.9 98.1 55.3 1.9 3.0 3.3 3.4 7.8 71.8 47.5 46.5 27.2 14.0 287.7 8.1 105.4 43.4 44.4 19.2 2.0 35.1 107.0 27.1 4.5 5.6 8.5 10.8 3.9 14.8 19.9 1.7 3.5 32.3 47.5 43.6 31.5 4.4 1.4 6.9 133.1 8.0 2.5 5.1 2.6 27.4 43.5 2.3 5.2 10.0 83.0 12.6 1.6 0.8 43.6 45.2 9.6 3.1 15.4 6.8 86.9 71.3 10.7 34.1 132.0 8.2 16.4 6.8 53.3 14.1 55.4 6.8 17.9 0.7 2.6 11.6 1.7 3.3 1.6 1.9 12.8 2.2 1.6 2.0 0.6 3.4 7.8 0.7 1.7 6.4 8.7 15.8 2.3 27.5 12.5 4.3 9.3 4.9 9.6 3.5 7.8 6.9 6.6 48.1 17.9 35.9 6.6 6.8 18.3 5.2 1.8 14.8 11.5 3.7 31.6 22.8 20.1 16.5 22.9 9.0 4.7 43.0 3.9 64.1 7.5 41.2 6.4 8.5 7.8 50.5 83.2 31.0 5.2 6.6 25.0 64.1 5.1 5.5 6.8 2.4 49.7 5.0 68.2 11.5 4.1 42.8 15.2 4.1 0.9 32.8 5.4 22.5 12.2 5.4 3.1 15.6 5.4 72.9 13.0 2.6 2.9 30.6 7.3 24.6 27.4 20.5 6.6 8.6 7.0 0.0 1.1 4.3 3.4 10.5 4.6 9.3 7.8 27.3 NCLN "NET59, NICALIN" ENSG00000125912 Nicalin Q969V3 19 3185563-3209575 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 115.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006625 Approved Approved "Nucleoplasm,Lipid droplets" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "HPA006625: AB_1079453" "unprognostic (4.32e-2)" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "prognostic favorable (1.19e-4)" "unprognostic (8.55e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.15e-4)" "unprognostic (9.27e-2)" "unprognostic (1.22e-1)" "unprognostic (9.38e-2)" "unprognostic (2.02e-2)" "unprognostic (1.26e-3)" "prognostic unfavorable (8.37e-5)" "prognostic favorable (8.82e-5)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (7.38e-2)" 25.8 62.4 19.7 16.2 18.5 33.3 22.3 18.6 25.2 23.1 13.9 36.5 31.1 25.9 4.3 31.0 23.4 6.9 28.0 22.2 15.7 29.5 59.8 33.1 12.7 20.4 18.8 22.0 53.6 11.0 23.5 7.5 18.6 28.9 8.7 3.5 22.9 8.0 29.2 25.8 35.8 8.6 17.4 42.8 29.7 21.8 21.1 8.6 24.4 10.5 6.6 26.3 21.7 17.5 70.8 74.2 21.6 60.3 20.3 15.4 55.4 84.5 33.2 57.5 45.5 103.6 36.8 43.3 67.0 49.4 37.8 87.2 24.7 57.1 12.7 57.4 61.3 31.7 46.2 73.2 41.1 56.8 51.3 29.0 36.2 46.4 24.7 15.2 31.7 41.7 84.1 41.4 25.6 59.3 48.9 64.1 59.3 43.2 63.6 77.8 23.2 71.9 36.5 42.6 45.3 47.1 31.1 56.2 50.3 10.3 38.3 61.9 47.6 45.4 45.8 77.3 100.4 59.0 58.1 36.0 51.1 71.5 72.7 1.4 13.4 9.8 7.1 13.1 5.8 5.4 4.3 7.9 9.2 4.5 4.6 6.2 7.6 4.8 5.6 18.8 4.2 9.6 19.7 18.5 18.6 25.2 22.2 15.7 20.4 18.8 18.6 17.4 21.1 17.5 15.3 16.0 14.7 12.1 19.8 8.3 9.4 18.2 5.7 15.1 15.6 11.9 10.2 15.7 14.8 11.0 10.4 20.4 26.0 71.0 3.9 31.0 15.0 11.3 15.6 14.3 12.6 12.4 13.6 37.4 49.3 14.9 30.5 17.4 15.9 31.1 12.8 43.8 39.3 23.5 14.6 41.2 14.2 18.8 9.2 49.1 9.3 18.1 14.2 8.4 19.2 5.8 14.4 9.0 10.3 35.8 45.3 9.1 51.7 22.0 75.7 11.7 10.5 13.2 13.1 11.8 16.9 13.6 20.1 12.4 12.5 17.0 12.0 115.1 72.7 14.2 NCOA6 "AIB3, ASC2, KIAA0181, NRC, PRIP, RAP250, TRBP" ENSG00000198646 "Nuclear receptor coactivator 6" Q14686 20 34689097-34825651 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 130.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004198, HPA050211" Supported Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA004198: AB_1078228, HPA050211: AB_2681052" "unprognostic (2.48e-1)" "unprognostic (4.81e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.65e-4)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.87e-2)" "unprognostic (1.51e-1)" "prognostic favorable (8.78e-5)" "unprognostic (9.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (4.42e-2)" 10.2 9.0 5.2 9.1 6.7 14.0 9.2 12.7 12.4 10.8 4.8 12.9 13.2 10.7 12.2 11.7 11.3 8.8 9.2 6.1 8.2 9.9 8.4 10.4 8.9 6.3 4.6 11.6 12.6 22.0 10.0 13.5 4.6 9.8 14.5 26.7 12.9 11.3 12.7 13.5 12.0 13.2 2.3 9.4 11.4 18.8 7.4 18.1 13.8 13.1 10.3 10.4 10.5 9.6 25.2 14.7 32.6 19.7 17.5 19.4 21.3 12.0 15.3 21.1 16.9 37.9 17.2 17.7 12.9 21.5 25.8 30.0 29.3 20.2 23.9 9.0 13.2 41.6 16.7 22.4 19.3 23.5 29.4 14.8 36.5 19.8 24.5 14.6 20.2 20.1 21.5 23.7 17.7 16.3 37.5 14.8 6.7 21.0 21.1 24.9 39.3 15.9 15.6 16.6 27.2 18.5 22.0 52.5 20.5 15.0 22.2 18.5 20.0 34.1 20.7 25.6 20.2 26.9 24.3 20.0 22.5 13.5 15.5 1.1 0.6 2.5 0.9 0.5 0.8 1.0 0.8 0.8 1.1 0.8 0.7 0.5 1.5 0.7 0.7 1.0 0.5 0.5 5.2 6.7 12.7 12.4 6.1 8.2 6.3 4.6 4.6 2.3 7.4 9.6 17.3 25.6 16.0 54.9 11.0 17.0 9.1 10.6 13.6 28.8 14.3 10.9 20.1 18.6 11.6 16.5 29.2 13.0 12.2 31.9 5.9 12.5 23.5 16.4 21.3 14.0 10.8 13.3 50.9 12.4 12.1 14.5 15.8 23.3 6.3 18.5 13.9 12.1 10.8 33.7 58.8 17.4 20.3 12.2 10.3 17.3 18.0 13.0 10.6 45.9 17.6 11.5 13.4 54.3 130.4 15.4 12.4 13.5 14.2 16.9 20.3 9.3 17.5 29.8 26.3 16.6 16.9 25.6 27.1 19.2 20.9 15.9 13.1 13.6 17.6 14.6 NCOR1 "hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1" ENSG00000141027 "Nuclear receptor corepressor 1" O75376 17 16029157-16218185 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043246, HPA050288, HPA051168, CAB072830" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "CAB072830: , HPA043246: AB_2678386, HPA050288: AB_2681073, HPA051168: AB_2681370" "unprognostic (1.83e-1)" "unprognostic (3.05e-1)" "unprognostic (9.17e-2)" "unprognostic (1.10e-1)" "unprognostic (7.38e-2)" "unprognostic (3.59e-2)" "unprognostic (2.55e-2)" "unprognostic (4.27e-2)" "unprognostic (4.87e-2)" "unprognostic (4.06e-2)" "unprognostic (7.07e-2)" "unprognostic (1.52e-2)" "prognostic favorable (7.92e-5)" "unprognostic (4.40e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-1)" "unprognostic (5.42e-2)" 22.1 18.3 37.8 28.1 39.7 42.8 29.0 60.8 84.7 27.3 41.0 44.0 47.1 30.7 20.3 30.6 25.1 26.4 23.4 39.3 34.7 33.6 46.2 26.9 29.9 32.7 35.7 33.5 34.2 42.3 17.1 28.3 31.0 27.6 40.6 41.4 22.4 31.4 42.0 31.6 38.2 29.7 28.2 29.3 42.7 32.4 35.4 51.9 34.8 39.9 34.7 28.8 18.3 43.4 68.0 110.6 77.7 65.1 62.4 47.1 38.6 48.9 54.8 52.4 47.1 59.8 30.3 70.9 33.6 85.9 39.3 50.4 96.4 59.2 77.3 95.6 71.1 70.7 96.3 71.1 60.8 45.3 80.7 48.5 60.6 81.2 94.4 45.2 73.9 98.0 63.0 28.8 52.3 44.3 79.3 29.1 38.6 118.6 29.9 78.1 78.5 33.5 54.9 76.0 26.5 43.8 80.7 34.7 37.7 197.5 33.5 50.3 65.5 53.7 32.6 39.9 68.3 19.7 25.0 40.4 51.0 52.4 47.0 408.4 104.8 240.4 126.9 86.0 106.7 188.4 144.0 141.0 76.3 191.4 139.8 139.0 205.2 139.9 112.3 130.3 144.7 98.8 37.8 39.7 60.8 84.7 39.3 34.7 32.7 35.7 31.0 28.2 35.4 43.4 90.9 80.1 113.2 116.2 130.0 67.8 106.2 91.3 86.0 150.3 76.8 60.8 91.5 82.9 86.9 53.3 158.4 102.1 121.7 198.1 35.2 95.5 69.7 75.7 109.5 88.4 87.9 132.1 127.0 96.5 101.7 77.1 149.4 103.7 87.3 88.9 67.5 126.4 76.1 129.5 122.2 118.8 81.4 81.9 76.7 43.6 101.5 96.7 37.4 107.7 172.8 83.1 197.8 123.1 151.4 111.7 148.3 121.5 88.5 95.6 194.4 46.7 63.8 167.1 92.1 106.0 106.2 98.7 90.2 78.0 68.2 87.6 142.1 89.5 153.0 122.9 NCSTN "APH2, KIAA0253" ENSG00000162736 Nicastrin Q92542 1 160343316-160358952 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021982, HPA054846, HPA070642" Approved Approved Cytosol NA NA 130000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB021982: , HPA054846: AB_2682624, HPA070642: AB_2686289" "unprognostic (1.08e-1)" "unprognostic (5.22e-3)" "unprognostic (1.51e-1)" "unprognostic (2.89e-2)" "unprognostic (1.19e-2)" "unprognostic (2.22e-2)" "unprognostic (1.69e-3)" "unprognostic (2.89e-1)" "unprognostic (3.30e-2)" "unprognostic (3.62e-2)" "unprognostic (8.21e-2)" "unprognostic (2.06e-2)" "prognostic unfavorable (7.75e-9)" "unprognostic (1.36e-3)" "unprognostic (3.15e-1)" "unprognostic (3.14e-2)" "unprognostic (4.89e-2)" 51.0 36.6 30.6 42.1 36.1 38.1 43.9 38.5 32.5 52.4 42.0 58.4 80.4 40.3 56.4 35.1 49.7 42.9 50.6 29.9 35.8 59.7 59.3 56.0 38.3 40.0 34.0 51.7 63.8 86.0 30.1 98.7 41.6 45.2 60.9 48.1 60.5 47.3 37.6 38.9 63.5 52.1 37.3 46.2 45.7 41.8 36.4 40.0 63.8 38.4 43.0 45.6 31.5 48.9 52.1 57.4 100.4 82.8 301.0 153.4 108.3 104.0 177.0 95.4 109.9 47.9 140.0 36.6 208.6 209.3 67.1 81.5 47.3 95.9 82.4 56.5 42.3 36.6 70.9 70.0 118.6 82.8 152.0 155.7 92.3 94.3 93.6 207.2 139.9 54.3 66.9 100.2 142.2 34.3 26.8 39.8 82.2 130.6 33.8 35.1 59.9 103.6 130.5 69.9 34.2 75.6 109.1 118.5 70.9 158.0 108.2 186.3 125.5 70.3 46.4 48.8 79.9 130.8 194.4 38.6 106.6 49.8 129.4 71.4 79.0 67.8 27.4 79.0 26.2 31.1 23.5 24.0 75.1 27.8 23.9 23.3 69.2 36.6 79.6 45.1 26.5 52.2 30.6 36.1 38.5 32.5 29.9 35.8 40.0 34.0 41.6 37.3 36.4 48.9 28.0 6.4 9.3 0.0 23.0 10.5 23.8 59.5 15.9 20.0 27.9 23.1 14.6 45.8 42.6 53.3 52.1 107.7 27.8 53.3 7.9 38.9 2.6 19.2 19.7 23.9 20.3 17.2 0.0 27.0 95.7 33.7 17.9 30.2 13.3 25.8 29.6 31.4 58.0 18.5 0.0 31.8 46.8 47.1 18.8 4.7 27.1 33.4 17.8 0.0 31.7 35.0 20.6 0.0 0.0 34.8 33.4 21.1 33.2 15.6 66.1 24.7 28.7 26.3 26.3 23.8 19.6 44.6 35.9 15.5 11.4 147.4 16.5 32.5 29.6 20.5 NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 106.5;placenta: 60.1;retina: 57.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Bipolar cells: 69.8;Early spermatids: 217.1;Late spermatids: 221.7" "Cancer enriched" "Detected in many" 4 "lung cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 48.5;U-266/70: 20.8;U-266/84: 85.8" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA048881: " "unprognostic (2.84e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-1)" "unprognostic (6.26e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (6.65e-4)" "unprognostic (2.18e-3)" "unprognostic (6.27e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.38e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-4)" "unprognostic (1.74e-1)" 4.8 2.6 1.1 0.9 1.7 0.0 3.2 4.7 1.2 14.2 9.3 6.5 2.9 6.0 4.3 7.7 20.4 9.4 5.2 1.8 2.6 27.1 0.4 106.5 0.3 8.8 12.9 42.5 0.5 0.7 5.3 60.1 15.2 16.7 8.3 57.4 2.2 4.4 4.3 1.7 4.7 3.5 7.6 0.3 4.1 10.4 3.7 2.4 1.3 14.0 0.2 9.0 1.9 5.4 0.2 0.0 10.6 0.0 13.9 11.3 0.2 0.2 0.5 0.2 0.5 1.6 0.0 0.0 0.0 48.5 0.8 0.0 0.0 0.0 1.1 0.9 1.7 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.2 0.6 0.0 0.0 0.0 14.3 1.0 0.0 0.2 0.1 0.9 7.4 2.1 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 2.6 0.2 0.0 0.0 11.5 0.0 0.2 0.5 20.8 85.8 0.0 3.9 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 4.7 1.2 1.8 2.6 8.8 12.9 15.2 7.6 3.7 5.4 10.9 246.8 48.3 1.6 0.0 1.1 0.0 0.0 0.0 69.8 0.2 0.1 1.6 8.6 28.6 12.9 18.8 0.3 0.0 5.3 0.0 0.0 217.1 0.9 4.7 11.7 1.8 0.0 0.0 0.2 0.0 14.9 0.0 0.1 2.5 0.1 2.9 0.0 0.1 1.7 8.0 0.8 0.0 0.0 0.8 221.7 3.4 0.4 5.4 6.5 0.0 12.2 0.0 0.0 0.0 0.1 0.5 0.7 0.0 0.0 0.0 0.0 12.5 20.0 0.0 1.2 3.6 6.4 5.0 0.3 0.9 0.5 0.3 13.0 1.2 0.1 NDP "EVR2, norrin" ENSG00000124479 "Norrin cystine knot growth factor NDP" Q00604 X 43948776-43973395 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision, Wnt signaling pathway" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;ovary: 46.2" "Group enriched" "Detected in some" 4 "Granulosa cells: 181.3;Muller glia cells: 105.5" "Cancer enriched" "Detected in many" 5 "glioma: 25.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "U-87 MG: 72.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003095 Supported Nucleoplasm,Nucleoli,Vesicles "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA003095: AB_1079457" "unprognostic (1.12e-1)" "unprognostic (7.12e-2)" "unprognostic (2.27e-2)" "unprognostic (2.55e-3)" "unprognostic (6.84e-3)" "unprognostic (1.51e-1)" "unprognostic (9.09e-2)" "unprognostic (2.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.47e-1)" "unprognostic (1.13e-1)" "unprognostic (2.87e-3)" 0.5 0.0 31.5 0.0 33.4 0.0 3.3 30.9 35.8 20.9 22.4 0.2 0.1 15.4 22.0 0.0 20.8 0.4 0.3 31.5 29.6 0.1 0.0 0.0 0.2 30.1 33.2 46.2 0.0 0.2 0.1 4.0 31.6 7.1 0.2 19.2 0.1 13.1 0.0 0.6 0.2 11.4 32.4 0.1 0.3 1.0 34.2 0.0 0.2 0.0 0.2 0.5 2.3 32.4 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 1.5 0.0 0.0 0.1 1.9 0.0 0.0 0.0 1.8 0.0 4.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 2.2 0.0 0.0 0.0 72.9 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 33.4 30.9 35.8 31.5 29.6 30.1 33.2 31.6 32.4 34.2 32.4 0.0 0.0 0.0 29.0 0.0 0.1 0.0 1.2 0.0 0.6 1.3 0.1 0.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 2.0 0.0 9.1 17.7 0.2 0.0 0.0 4.2 0.0 0.3 0.9 0.0 17.0 0.0 181.3 0.0 0.0 0.1 0.0 0.8 0.0 2.0 0.0 0.0 0.7 13.4 0.6 0.0 0.0 0.0 105.5 0.0 1.5 9.5 1.2 0.0 9.8 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 5.4 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 NDST1 "HSST, NST1" ENSG00000070614 "N-deacetylase and N-sulfotransferase 1" P52848 5 150485818-150558211 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Multifunctional enzyme, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 1.4;classical monocyte: 5.5;eosinophil: 3.6;intermediate monocyte: 1.7;myeloid DC: 4.2;neutrophil: 5.4;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 10 "dendritic cells: 4.2;granulocytes: 5.4;monocytes: 5.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060532 Approved NA NA 1400000 "Cluster 14: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA060532: AB_2684310" "unprognostic (1.36e-1)" "unprognostic (5.54e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (6.99e-4)" "unprognostic (1.77e-1)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.47e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (5.13e-4)" "unprognostic (4.97e-3)" "unprognostic (6.92e-2)" "unprognostic (7.45e-2)" "unprognostic (2.46e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.08e-2)" 37.2 22.7 39.4 14.0 45.1 7.6 28.6 43.8 38.9 16.0 3.9 17.6 12.5 17.3 7.9 38.8 14.7 15.2 26.8 30.8 30.7 15.4 42.6 34.3 7.3 62.6 48.8 23.0 39.7 20.5 6.7 12.2 50.3 14.5 9.5 13.9 37.4 16.8 23.6 34.2 17.4 19.2 47.8 43.4 16.0 14.5 51.5 4.2 22.9 13.0 9.9 14.1 18.7 60.0 32.4 28.3 46.1 56.4 45.3 44.9 46.3 58.1 75.9 56.8 84.8 84.1 33.3 22.0 57.6 116.8 91.0 54.4 25.1 118.0 37.6 2.6 38.9 26.0 18.5 13.2 33.5 19.5 45.5 61.6 48.1 68.7 31.0 56.9 78.3 12.9 25.3 7.8 56.3 27.5 2.3 6.2 21.6 9.1 33.0 37.6 38.4 9.8 33.4 32.5 13.8 48.3 35.2 108.5 46.3 32.7 58.3 4.8 38.8 96.4 86.2 42.3 48.3 17.1 4.7 8.1 79.2 30.1 38.0 1.4 5.5 3.6 0.1 1.7 0.0 0.4 0.0 0.4 4.2 0.1 0.0 0.2 5.4 0.0 4.7 0.3 0.0 2.8 39.4 45.1 43.8 38.9 30.8 30.7 62.6 48.8 50.3 47.8 51.5 60.0 29.8 38.5 8.7 23.8 1.9 5.7 3.5 14.4 6.2 11.6 29.9 15.4 11.5 17.2 9.6 16.5 8.4 8.6 0.5 20.9 1.9 10.4 0.7 5.5 7.7 35.5 1.2 3.2 12.0 10.5 11.3 11.0 2.0 6.8 1.3 20.4 31.8 47.5 7.7 13.5 11.7 5.3 8.2 14.4 7.6 1.9 12.5 8.7 10.6 16.9 7.4 12.1 0.0 12.1 39.7 18.8 6.6 32.0 3.7 7.9 17.8 8.8 3.8 11.3 0.0 8.7 11.5 0.7 1.6 17.4 12.4 4.5 1.2 11.8 5.8 5.3 NDST3 HSST3 ENSG00000164100 "N-deacetylase and N-sulfotransferase 3" O95803 4 118033618-118258634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.8;liver: 1.3;lymphoid tissue: 2.9;retina: 2.7" "Group enriched" "Detected in some" 5 "Excitatory neurons: 299.6;Inhibitory neurons: 128.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "MOLT-4: 17.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056189 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA056189: AB_2683061" "unprognostic (1.95e-2)" "unprognostic (7.58e-2)" "unprognostic (4.34e-3)" "unprognostic (2.55e-7)" "unprognostic (4.05e-2)" "unprognostic (2.18e-2)" "unprognostic (2.86e-3)" "unprognostic (2.32e-2)" "unprognostic (1.87e-1)" "unprognostic (1.46e-2)" "unprognostic (7.43e-2)" "unprognostic (1.99e-2)" "unprognostic (1.09e-3)" "unprognostic (1.37e-1)" "unprognostic (4.39e-3)" "unprognostic (6.83e-2)" "unprognostic (8.85e-2)" 0.0 0.5 1.2 0.0 4.8 0.0 0.0 3.3 2.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.5 1.0 0.1 1.3 0.0 0.1 0.6 0.8 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.2 0.0 0.4 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.6 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 4.8 3.3 2.8 1.5 1.0 0.6 0.8 0.0 0.0 0.4 0.0 0.2 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 20.7 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 299.6 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.4 0.6 0.1 6.7 128.6 0.2 0.0 42.1 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.3 0.0 12.1 18.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 NDST4 ENSG00000138653 "N-deacetylase and N-sulfotransferase 4" Q9H3R1 4 114827763-115113876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 9.0" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 29.3;Oligodendrocyte precursor cells: 15.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "hypothalamus: 2.3;medulla oblongata: 8.3;midbrain: 3.5;pons: 9.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.9;CACO-2: 3.7;RH-30: 14.5;T-47d: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011129 Uncertain NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA011129: AB_1079460" "unprognostic (5.58e-2)" "unprognostic (5.90e-2)" "unprognostic (4.82e-1)" "unprognostic (1.71e-2)" "unprognostic (1.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.94e-1)" "unprognostic (6.55e-2)" 0.0 0.0 0.7 0.0 1.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.6 2.3 0.0 0.0 0.0 0.0 8.3 3.5 1.5 0.0 0.0 0.0 0.0 9.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.6 0.7 0.3 0.2 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.1 0.0 0.2 0.6 2.3 8.3 3.5 9.0 0.6 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 29.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 15.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 NDUFA10 CI-42k ENSG00000130414 "NADH:ubiquinone oxidoreductase subunit A10" O95299 2 239892450-240025743 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 332.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059529, HPA067045, CAB070846" Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB070846: AB_11152346, HPA059529: AB_2684051, HPA067045: AB_2732756" "unprognostic (2.12e-2)" "unprognostic (8.94e-3)" "unprognostic (8.73e-2)" "unprognostic (2.02e-2)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (5.71e-2)" "unprognostic (2.47e-2)" "unprognostic (1.05e-1)" "prognostic favorable (2.09e-7)" "unprognostic (1.16e-1)" "unprognostic (4.96e-2)" "unprognostic (1.98e-1)" "unprognostic (2.95e-1)" 55.4 91.1 36.3 29.6 40.2 50.3 50.3 39.8 51.2 41.0 38.9 83.2 81.6 37.8 28.3 74.6 43.6 31.2 184.8 41.7 36.0 94.2 103.6 35.4 32.3 41.9 39.4 45.4 58.5 99.3 38.5 37.9 41.3 33.1 84.3 31.2 55.9 33.1 206.4 72.4 64.3 39.8 34.0 37.7 71.7 35.3 37.7 45.3 38.8 332.0 49.7 47.3 49.2 39.4 74.4 65.5 46.3 81.5 54.8 95.4 75.5 49.0 70.9 71.3 77.8 72.8 82.8 51.0 31.8 64.2 60.8 96.2 109.8 103.1 92.6 59.7 90.9 72.9 65.6 174.6 72.4 96.9 58.6 95.5 80.3 68.5 85.0 66.6 96.6 74.6 102.0 34.8 81.8 124.8 95.6 110.5 56.3 114.4 81.0 93.2 114.4 81.2 108.7 152.1 70.5 54.6 55.3 131.8 108.9 33.3 121.2 97.4 69.9 52.7 60.7 70.7 75.8 77.3 24.6 79.2 60.3 80.9 72.8 30.2 106.3 47.1 72.9 115.8 93.8 95.4 70.7 77.5 147.9 77.0 68.2 69.4 26.7 97.6 103.3 49.7 92.7 104.6 36.3 40.2 39.8 51.2 41.7 36.0 41.9 39.4 41.3 34.0 37.7 39.4 66.8 76.9 74.1 31.6 63.5 104.9 96.5 193.5 60.3 80.8 88.4 89.5 354.8 87.2 114.0 77.3 62.6 216.4 58.1 137.3 311.0 112.5 47.5 66.8 83.2 67.4 92.9 57.6 83.1 78.5 124.0 71.7 62.2 76.6 65.9 103.7 66.4 139.1 125.2 50.5 68.5 152.3 103.7 90.5 82.0 85.3 50.1 65.2 112.1 27.2 107.8 72.2 53.5 37.7 71.4 77.7 125.5 49.2 56.7 62.1 182.7 303.0 77.7 110.4 65.7 74.6 77.3 84.2 73.4 107.2 118.9 218.1 63.0 185.3 234.2 110.0 NDUFA5 "B13, CI-13kB, CI-13KD-B, NUFM, UQOR13" ENSG00000128609 "NADH:ubiquinone oxidoreductase subunit A5" Q16718 7 123536997-123557904 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 403.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 717.3;Distal tubular cells: 1070.2;Proximal tubular cells: 667.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043175 Supported NA NA 81000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA043175: AB_10793992" "prognostic favorable (8.47e-5)" "unprognostic (4.00e-2)" "unprognostic (1.82e-1)" "unprognostic (2.04e-1)" "unprognostic (4.90e-2)" "unprognostic (3.26e-1)" "unprognostic (2.23e-1)" "unprognostic (3.46e-2)" "unprognostic (1.81e-1)" "unprognostic (2.14e-2)" "unprognostic (1.37e-1)" "unprognostic (9.20e-2)" "prognostic favorable (3.99e-9)" "unprognostic (3.39e-1)" "unprognostic (1.59e-1)" "unprognostic (1.93e-1)" "unprognostic (2.73e-3)" 55.2 129.2 94.7 34.1 99.9 34.8 68.8 94.2 130.1 51.3 93.4 78.5 77.6 47.5 71.5 51.0 51.8 47.0 215.7 100.5 108.4 175.3 114.9 44.4 40.0 92.4 97.6 42.2 41.2 170.1 58.3 39.7 98.5 72.8 73.3 127.1 75.6 63.1 285.1 27.2 72.7 46.9 92.6 35.4 77.4 38.3 94.4 52.8 136.6 403.3 42.5 57.8 33.5 91.6 65.9 41.8 76.3 76.6 64.5 58.6 39.5 57.4 63.1 46.8 61.1 47.1 58.2 108.6 54.8 58.8 91.0 60.7 83.9 75.2 74.3 89.6 71.7 68.8 85.9 78.1 62.7 140.5 56.4 58.6 65.9 45.3 47.3 84.1 68.4 75.4 213.9 104.9 84.4 45.5 127.3 162.1 100.3 154.3 107.0 69.2 75.0 146.6 129.5 63.7 144.9 86.3 76.1 286.2 90.3 102.5 65.6 104.7 53.1 58.9 31.7 262.0 88.5 111.2 109.4 116.4 112.7 106.2 75.7 57.8 26.2 31.5 38.2 48.7 55.4 53.6 48.6 44.9 37.1 41.6 52.5 54.0 9.2 52.7 54.8 40.0 55.8 60.4 94.7 99.9 94.2 130.1 100.5 108.4 92.4 97.6 98.5 92.6 94.4 91.6 99.2 102.5 100.4 38.2 108.7 112.5 146.2 280.3 74.6 183.6 113.0 100.8 717.3 102.9 160.6 165.5 83.4 160.6 105.6 119.0 1070.2 132.2 359.6 123.4 91.1 91.8 138.0 91.1 65.2 89.6 156.8 110.5 108.6 128.6 88.7 59.2 66.0 170.6 109.6 127.9 48.5 168.6 295.0 67.2 92.5 77.5 90.1 94.9 202.7 19.7 65.7 264.6 77.2 32.2 29.2 86.2 130.9 112.1 82.0 107.1 210.2 667.6 158.6 214.7 118.3 97.4 133.7 179.0 99.0 94.7 110.2 158.4 102.3 116.9 172.2 147.0 NDUFB5 "CI-SGDH, MGC12314, SGDH" ENSG00000136521 "NADH:ubiquinone oxidoreductase subunit B5" O43674 3 179604690-179627647 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 241.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005640 Enhanced Supported Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA005640: AB_1079461" "unprognostic (6.76e-2)" "unprognostic (1.09e-2)" "unprognostic (6.33e-2)" "unprognostic (3.51e-3)" "unprognostic (1.38e-1)" "unprognostic (7.35e-3)" "unprognostic (1.33e-2)" "unprognostic (1.63e-1)" "unprognostic (4.46e-2)" "unprognostic (5.96e-3)" "unprognostic (4.83e-2)" "unprognostic (7.11e-2)" "prognostic favorable (3.32e-5)" "unprognostic (3.05e-1)" "unprognostic (1.36e-1)" "unprognostic (6.50e-2)" "unprognostic (1.95e-1)" 61.0 88.4 35.6 29.0 38.5 19.5 47.8 39.4 57.3 37.7 52.8 64.0 75.1 30.2 15.6 56.7 33.4 28.8 217.0 38.4 40.0 93.5 74.0 34.4 36.1 37.1 36.6 41.9 52.3 66.6 40.2 27.0 37.4 32.6 36.1 22.7 43.7 20.2 241.4 43.6 57.0 22.3 35.4 46.3 63.8 42.2 39.8 31.4 41.6 166.9 24.8 46.2 41.5 38.9 96.5 23.2 51.2 66.8 52.3 66.0 75.6 58.5 42.0 48.1 50.7 79.8 53.4 72.7 193.4 32.7 119.5 89.9 48.9 47.4 38.9 182.5 43.1 90.4 31.2 44.8 52.3 97.9 64.0 64.9 60.7 31.2 51.0 61.0 62.8 62.1 71.2 98.7 51.8 68.8 55.8 60.5 80.2 138.7 80.8 64.2 63.3 205.1 82.5 46.8 41.1 62.4 34.9 169.9 126.7 36.2 265.9 151.2 64.5 46.6 47.8 61.7 139.9 158.0 193.6 122.5 75.8 91.7 67.9 94.6 104.5 49.9 43.8 127.8 64.5 90.2 60.0 51.6 145.5 67.2 59.8 62.9 18.9 48.1 154.8 81.0 84.0 105.6 35.6 38.5 39.4 57.3 38.4 40.0 37.1 36.6 37.4 35.4 39.8 38.9 113.6 48.1 48.5 17.3 90.2 85.1 115.2 374.4 73.4 45.9 121.0 138.6 362.3 88.6 164.3 88.3 33.3 234.0 54.5 115.9 508.7 132.5 162.6 118.4 79.0 89.2 117.5 75.3 16.1 105.7 150.0 87.1 77.5 62.9 93.8 120.1 105.7 118.3 253.5 40.4 22.6 196.0 266.5 261.3 133.0 28.9 81.1 133.6 135.2 15.9 180.0 107.2 70.0 19.6 25.8 81.5 163.4 70.0 75.0 89.8 293.5 462.8 157.9 73.4 72.3 87.1 98.5 265.7 128.3 105.9 88.7 230.0 72.9 257.4 268.8 163.4 NDUFS8 "CI-23k, TYKY" ENSG00000110717 "NADH:ubiquinone oxidoreductase core subunit S8" O00217 11 68030617-68036644 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 833.5;Late spermatids: 797.2;Proximal tubular cells: 927.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018524, HPA067429" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA018524: AB_1854355, HPA067429: " "unprognostic (2.90e-1)" "unprognostic (1.41e-3)" "unprognostic (2.41e-1)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-1)" "unprognostic (7.75e-2)" "unprognostic (3.15e-1)" "unprognostic (1.77e-2)" "unprognostic (3.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (3.27e-8)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (9.45e-2)" 99.2 308.4 141.2 38.8 153.2 56.2 87.7 157.2 180.4 73.2 172.3 142.0 81.4 89.2 27.2 115.3 81.3 29.1 468.2 144.2 152.0 188.6 152.0 73.1 42.2 149.6 144.9 68.2 97.7 74.6 130.6 33.6 145.8 118.2 36.7 49.5 96.2 66.7 406.4 93.0 84.4 39.0 142.2 76.9 137.8 104.7 154.0 40.3 101.8 275.5 30.1 94.4 76.0 150.2 152.9 366.4 94.6 137.0 70.9 63.5 132.4 102.3 88.5 155.6 118.9 338.4 159.6 118.4 186.8 85.9 134.6 181.2 108.8 128.4 53.1 139.4 264.9 107.2 217.1 186.3 171.8 99.1 112.1 80.5 126.5 111.1 124.8 82.0 106.2 159.9 110.3 121.1 99.2 358.6 219.2 216.9 125.2 377.7 308.0 154.4 95.9 384.9 192.8 123.3 125.5 102.2 75.7 171.7 392.3 66.5 245.6 105.9 84.1 155.6 133.9 224.8 148.8 165.2 188.5 99.7 252.3 121.8 111.2 84.7 220.1 124.0 182.4 232.0 170.1 183.3 154.6 165.5 309.4 156.3 146.2 164.2 20.7 309.6 131.7 324.3 202.2 232.4 141.2 153.2 157.2 180.4 144.2 152.0 149.6 144.9 145.8 142.2 154.0 150.2 88.7 89.8 90.1 18.6 92.3 85.4 95.5 284.3 104.7 83.4 147.2 156.7 301.9 143.0 164.9 213.3 54.2 279.6 97.8 301.0 833.5 200.8 225.7 101.1 74.8 85.3 205.0 149.8 13.6 199.3 165.9 109.6 147.3 79.7 95.8 156.5 73.5 231.7 276.6 50.5 19.3 277.2 240.1 124.1 108.0 797.2 100.6 128.7 163.7 13.1 187.4 143.6 128.8 12.1 15.4 173.7 194.9 108.0 157.8 118.6 337.1 927.8 120.8 118.7 59.2 81.2 208.6 105.9 72.7 209.7 116.2 172.4 102.7 278.7 318.2 139.1 NDUFV1 CI-51K ENSG00000167792 "NADH:ubiquinone oxidoreductase core subunit V1" P49821 11 67605653-67612554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 526.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 482.4;Proximal tubular cells: 499.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045211, HPA075051" Enhanced Supported Mitochondria,Cytosol No No 37000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA045211: AB_10962830, HPA075051: AB_2686732" "unprognostic (4.57e-2)" "unprognostic (2.17e-2)" "unprognostic (2.84e-1)" "unprognostic (7.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.54e-3)" "unprognostic (1.19e-1)" "unprognostic (3.31e-2)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "unprognostic (4.02e-2)" "unprognostic (3.03e-2)" "prognostic favorable (7.49e-10)" "unprognostic (1.12e-2)" "unprognostic (1.80e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" 95.0 126.5 87.6 52.5 93.7 72.5 90.9 105.6 107.1 93.9 104.8 142.3 124.5 85.2 33.8 114.0 84.6 47.1 400.2 91.6 97.0 188.4 187.0 77.1 66.7 103.3 91.5 101.9 117.2 169.8 84.5 46.7 110.4 77.4 73.7 81.6 90.2 73.2 526.2 117.7 96.6 51.1 86.9 98.8 132.0 76.0 104.9 51.6 107.6 440.5 62.8 88.1 88.6 99.9 132.9 133.6 68.8 141.3 85.6 83.4 130.6 84.1 76.4 122.2 82.6 256.8 155.3 241.9 167.3 69.2 99.7 176.8 146.1 126.4 38.4 125.2 114.9 100.0 189.1 127.9 119.0 136.9 106.9 126.7 119.0 100.4 88.0 76.9 109.3 173.9 180.9 192.6 75.8 190.2 163.1 268.0 68.5 295.3 168.8 184.5 135.8 399.1 99.3 95.3 109.9 104.6 104.3 347.4 275.3 46.0 177.4 138.0 90.7 118.9 88.8 172.3 87.5 187.7 116.8 122.6 138.0 144.6 117.7 39.0 72.8 38.1 65.1 83.4 71.6 59.8 55.0 63.2 110.7 60.1 50.2 63.7 13.1 104.0 51.2 73.0 78.1 77.0 87.6 93.7 105.6 107.1 91.6 97.0 103.3 91.5 110.4 86.9 104.9 99.9 54.6 60.9 75.0 33.3 76.2 80.3 95.9 187.6 77.4 68.7 82.1 94.4 482.4 61.5 120.7 86.5 50.1 203.5 72.8 235.7 397.2 114.9 74.0 43.1 47.5 56.7 98.5 85.0 32.9 112.1 158.8 82.4 137.1 55.2 61.4 99.6 56.4 136.2 136.5 63.9 36.5 155.9 152.5 68.8 81.4 222.7 65.6 68.4 113.8 13.1 81.0 89.3 60.8 19.1 34.6 70.1 122.8 59.0 146.6 55.0 199.4 499.2 80.3 78.5 46.0 90.8 136.9 100.7 83.3 127.0 80.6 189.1 79.3 145.9 274.8 111.7 NECAB3 "APBA2BP, dJ63M2.4, dJ63M2.5, EFCBP3, NIP1, SYTIP2, XB51" ENSG00000125967 "N-terminal EF-hand calcium binding protein 3" Q96P71 20 33657087-33674463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 93.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044785, HPA070595, HPA071786" Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "HPA044785: AB_2679086, HPA070595: AB_2732158, HPA071786: AB_2732186" "unprognostic (8.95e-2)" "unprognostic (1.45e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.44e-1)" "unprognostic (4.05e-2)" "unprognostic (1.17e-1)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "prognostic favorable (3.19e-5)" "unprognostic (3.13e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (6.13e-2)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-1)" 10.2 55.9 20.1 2.2 21.2 1.5 10.4 18.9 33.9 11.8 20.4 14.4 13.6 9.1 6.9 8.9 10.9 4.5 45.7 21.7 21.2 13.3 13.3 11.1 2.3 23.3 19.1 41.2 19.1 17.5 10.3 3.9 24.4 27.2 4.4 6.5 13.6 7.8 60.3 6.9 10.6 3.7 16.6 6.5 30.5 10.6 23.2 1.9 19.2 31.7 1.7 14.6 10.0 22.3 8.2 7.1 5.1 10.5 4.0 7.8 24.6 11.2 4.2 7.1 6.2 33.2 5.3 9.1 26.2 6.6 16.7 9.7 5.3 3.3 2.6 3.2 7.7 8.7 30.7 39.3 10.5 2.1 8.0 9.7 4.8 6.6 2.1 7.6 4.8 4.8 12.6 4.8 9.3 12.5 3.3 8.6 2.2 8.7 17.5 9.7 13.3 15.9 6.6 6.1 32.4 9.0 26.1 28.7 12.0 5.6 36.6 10.4 4.0 8.6 12.4 11.3 12.7 17.7 7.8 17.1 16.9 4.0 3.8 0.0 1.3 1.8 0.3 1.3 0.9 0.2 0.6 0.3 1.2 0.9 0.4 0.1 0.0 1.2 3.5 0.0 1.6 0.6 20.1 21.2 18.9 33.9 21.7 21.2 23.3 19.1 24.4 16.6 23.2 22.3 5.4 16.0 45.5 14.7 4.1 3.1 6.5 2.7 8.6 19.4 20.5 11.6 29.9 10.0 5.9 5.5 8.4 20.6 3.8 22.5 33.2 3.7 93.1 5.7 7.2 2.4 19.9 4.0 13.0 7.5 26.1 12.5 26.5 5.4 3.8 14.0 2.2 9.1 8.9 8.4 14.5 16.2 4.1 6.0 6.2 54.0 26.4 5.5 12.4 1.0 3.6 18.2 2.1 6.0 4.5 4.4 15.1 23.7 11.7 14.2 45.9 12.2 3.8 20.8 6.6 9.2 12.1 20.5 20.6 9.3 3.1 20.7 5.4 23.9 20.0 10.0 NECTIN1 "CD111, CLPED1, ED4, HIgR, HVEC, OFC7, PRR, PRR1, PVRL1, PVRR1, SK-12" ENSG00000110400 "Nectin cell adhesion molecule 1" Q15223 11 119623408-119729200 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 128.8;skin 1: 134.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 12.1;Breast myoepithelial cells: 27.3;Exocrine glandular cells: 12.3;Granulosa cells: 68.7;Pancreatic endocrine cells: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 229.2;hTCEpi: 139.2;RT4: 157.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016135, HPA026846" Approved "Secreted in other tissues" NA NA 180000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "CAB016135: AB_626865, HPA026846: AB_1846226" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (3.87e-2)" "unprognostic (1.26e-1)" "unprognostic (3.20e-2)" "unprognostic (2.25e-3)" "unprognostic (2.03e-1)" "unprognostic (3.76e-2)" "unprognostic (3.42e-1)" "unprognostic (3.58e-2)" "unprognostic (3.28e-1)" "unprognostic (3.59e-3)" "unprognostic (2.13e-2)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (9.62e-2)" 4.4 4.0 14.8 4.7 25.6 24.3 8.2 17.4 32.3 14.0 0.0 12.4 16.6 3.4 2.3 128.8 4.0 3.4 8.1 30.5 15.3 5.1 4.3 3.4 2.1 23.8 26.5 2.3 18.8 2.7 7.8 7.3 18.4 12.8 12.9 18.5 18.0 6.2 1.9 134.4 12.0 4.5 16.3 3.3 4.6 1.3 26.9 6.7 2.2 1.6 27.9 28.9 36.8 38.8 16.6 13.6 12.6 18.2 6.5 2.1 88.2 6.6 6.1 5.4 3.8 28.8 55.2 21.8 26.1 7.6 10.9 229.2 32.5 117.6 2.4 51.8 4.9 3.0 4.4 13.2 2.6 14.9 35.4 2.0 139.2 17.1 62.5 2.1 16.3 6.2 0.6 113.2 7.2 42.7 0.3 9.0 41.6 55.3 18.7 1.2 75.7 26.3 5.1 157.4 30.6 68.6 22.1 57.4 1.8 18.8 52.3 2.2 9.0 4.8 17.6 39.2 5.9 20.6 28.0 0.2 1.7 11.9 11.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 1.6 0.0 0.0 14.8 25.6 17.4 32.3 30.5 15.3 23.8 26.5 18.4 16.3 26.9 38.8 4.2 0.0 3.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 12.1 27.3 0.0 0.0 4.3 1.8 0.0 4.1 4.1 0.0 0.0 8.7 0.0 4.6 3.2 1.3 0.0 0.0 0.0 12.3 1.3 2.1 0.0 10.9 0.0 68.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.5 0.0 0.0 1.9 0.0 0.0 3.3 1.5 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 8.9 1.3 1.7 0.0 0.0 NECTIN3 "CD113, CDw113, DKFZP566B0846, nectin-3, PPR3, PVRL3, PVRR3" ENSG00000177707 "Nectin cell adhesion molecule 3" Q9NQS3 3 111070071-111275563 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 54.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Syncytiotrophoblasts: 117.3;Theca cells: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 117.4;TIME: 170.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009869, HPA011038" Approved Approved "Cell Junctions,Cytosol" NA NA 41000000 "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "Cell Junctions" "CAB009869: AB_2284699, HPA011038: AB_1079719" "unprognostic (3.76e-2)" "unprognostic (3.81e-3)" "unprognostic (1.74e-1)" "unprognostic (1.97e-2)" "unprognostic (1.02e-1)" "unprognostic (9.77e-2)" "unprognostic (3.26e-3)" "unprognostic (3.77e-1)" "unprognostic (7.58e-2)" "unprognostic (3.94e-2)" "unprognostic (5.33e-2)" "unprognostic (7.04e-2)" "prognostic favorable (9.82e-7)" "unprognostic (2.01e-1)" "unprognostic (1.97e-1)" "unprognostic (2.67e-1)" "unprognostic (1.05e-1)" 8.9 4.8 3.9 4.7 6.0 0.2 4.3 6.2 7.5 7.3 0.0 23.0 32.9 7.6 1.5 4.6 9.7 8.2 5.3 6.6 5.0 12.0 29.4 10.4 3.0 10.8 5.6 16.1 7.1 4.6 1.1 22.7 6.7 11.7 23.1 7.3 5.6 8.4 1.7 1.4 21.2 13.6 7.3 3.9 24.6 54.7 12.4 1.5 42.5 7.1 3.1 6.0 3.0 8.8 0.2 36.2 117.4 7.7 45.7 85.3 7.2 78.6 82.7 47.8 39.7 33.4 16.7 0.0 25.4 112.4 26.6 0.6 33.2 11.4 87.4 0.9 8.8 0.1 12.1 2.4 77.2 5.9 1.1 43.6 4.6 31.7 30.3 42.5 40.8 1.5 0.0 30.2 104.2 0.2 7.8 0.0 33.0 11.0 12.9 0.0 58.2 0.2 26.9 19.2 2.9 20.8 1.6 0.0 15.7 38.9 1.3 0.5 170.4 58.8 24.9 11.1 47.2 17.2 0.0 0.2 37.9 0.1 56.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 6.0 6.2 7.5 6.6 5.0 10.8 5.6 6.7 7.3 12.4 8.8 8.3 25.6 11.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.6 3.0 0.0 0.0 3.1 12.9 0.0 3.9 4.5 0.0 0.0 6.5 0.0 9.0 11.4 4.4 0.0 0.0 0.0 18.9 9.4 9.5 0.0 13.7 1.3 6.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 2.8 0.0 0.0 7.1 0.7 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 117.3 5.3 31.5 0.0 0.0 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "NEDD4 like E3 ubiquitin protein ligase" Q96PU5 18 58044226-58401540 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 253.2;Excitatory neurons: 280.9" "Cancer enhanced" "Detected in all" "prostate cancer: 29.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "T-reg: 5.1" "Lineage enriched" "Detected in many" 4 "T-cells: 5.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 146.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 11.2 16.8 20.9 6.7 34.4 27.0 25.8 25.1 31.3 7.6 0.7 38.8 18.7 5.3 10.0 12.0 9.1 9.5 26.9 32.3 16.2 53.4 36.5 47.9 4.1 10.9 18.4 6.4 60.5 13.6 28.4 12.0 10.4 64.2 42.8 20.5 27.5 20.4 34.0 11.2 33.8 6.2 8.6 7.9 51.5 7.8 16.7 4.5 17.4 13.1 7.9 19.4 5.9 16.3 70.7 24.5 14.6 20.9 5.1 2.1 49.8 19.2 88.2 48.6 74.6 28.6 37.1 15.1 57.7 7.4 51.3 50.3 19.5 86.1 100.8 34.9 15.5 10.6 14.3 111.3 2.4 0.5 6.0 13.0 54.6 66.4 78.8 39.1 4.0 13.2 18.7 6.3 20.0 16.2 1.0 1.0 12.2 26.7 33.3 14.3 20.1 17.6 47.0 88.7 17.5 5.0 16.1 5.1 146.1 28.3 29.4 5.6 28.8 131.5 38.5 7.5 83.4 8.3 15.3 9.5 27.6 10.8 10.8 0.7 0.3 1.2 0.2 0.3 0.5 0.8 0.6 0.1 0.1 0.3 0.3 0.2 0.2 0.3 0.1 0.1 5.1 0.3 20.9 34.4 25.1 31.3 32.3 16.2 10.9 18.4 10.4 8.6 16.7 16.3 6.0 253.2 144.8 110.4 5.1 112.8 161.2 34.0 86.6 18.1 99.5 65.9 47.8 64.3 112.8 62.5 173.0 13.0 3.6 144.5 49.0 35.7 22.6 64.0 7.3 14.7 45.2 57.9 280.9 49.2 4.7 9.5 114.7 75.0 3.8 4.7 17.5 41.3 7.3 62.2 173.3 201.5 101.7 8.4 8.2 6.6 3.4 13.3 14.2 88.1 7.3 45.2 2.1 11.1 105.0 49.9 145.3 17.7 12.7 126.9 127.3 91.6 72.7 10.0 0.0 34.3 6.0 1.1 12.5 62.3 53.0 80.0 6.6 8.2 72.9 155.5 NELFE "D6S45, NELF-E, RD, RDBP, RDP" ENSG00000204356 "Negative elongation factor complex member E" P18615 6 31952087-31959038 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 635.4;Late spermatids: 1699.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007187, HPA007594, HPA046502" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA007187: AB_1856161, HPA007594: AB_2667867, HPA046502: AB_2679677" "unprognostic (1.09e-1)" "unprognostic (3.28e-1)" "unprognostic (1.45e-1)" "unprognostic (6.33e-3)" "unprognostic (4.43e-2)" "unprognostic (4.25e-2)" "unprognostic (7.71e-3)" "unprognostic (1.34e-1)" "unprognostic (1.95e-1)" "unprognostic (1.46e-2)" "unprognostic (1.97e-1)" "unprognostic (7.78e-2)" "prognostic unfavorable (2.70e-4)" "unprognostic (5.21e-2)" "unprognostic (1.07e-1)" "unprognostic (2.21e-1)" "unprognostic (3.68e-2)" 51.9 48.5 37.4 15.2 38.2 23.5 49.4 38.6 40.3 47.9 36.6 45.9 12.7 50.1 26.9 51.7 46.9 11.9 57.1 35.8 39.2 50.0 24.5 43.6 16.9 39.1 38.3 47.4 52.4 41.1 42.5 20.5 37.4 35.4 24.2 6.3 40.5 26.7 58.2 51.3 37.2 27.7 38.7 38.7 46.6 166.2 39.2 36.8 39.6 30.8 25.4 44.1 43.5 39.6 51.8 59.9 55.5 48.4 54.7 59.9 50.9 40.3 73.8 90.1 74.6 69.5 35.7 49.0 41.3 79.0 117.1 44.0 47.4 85.7 64.5 39.4 63.2 35.9 41.9 80.5 110.6 43.4 29.0 63.2 119.2 96.2 113.5 75.6 84.2 87.6 51.6 56.6 90.2 89.6 77.1 44.6 22.9 79.6 68.1 63.0 49.1 95.2 61.0 49.8 42.3 52.8 30.4 44.4 80.1 48.4 66.0 89.6 37.1 39.7 63.5 34.5 67.8 65.9 77.8 47.6 26.0 36.4 69.8 44.9 60.4 58.7 49.4 68.8 46.2 50.9 45.4 47.2 56.9 49.9 41.9 41.0 31.4 48.8 67.8 45.4 49.0 55.4 37.4 38.2 38.6 40.3 35.8 39.2 39.1 38.3 37.4 38.7 39.2 39.6 49.0 16.0 27.9 4.6 42.8 47.2 69.0 61.5 40.5 15.5 55.1 62.5 47.2 72.9 43.1 33.1 12.5 98.4 37.7 84.6 133.1 93.3 635.4 68.4 40.8 49.8 34.2 52.2 6.2 136.5 112.1 47.7 31.1 45.6 45.6 46.7 45.3 34.8 82.8 11.8 6.2 71.1 46.8 55.3 42.6 1699.6 71.1 45.0 49.8 3.7 73.2 65.5 51.5 6.6 9.9 113.1 99.1 45.1 68.6 79.6 124.8 107.7 112.5 25.6 32.9 48.7 84.9 224.7 91.0 54.2 41.8 114.4 41.7 41.0 72.4 64.6 NELL1 "FLJ45906, IDH3GL" ENSG00000165973 "Neural EGFL like 1" Q92832 11 20669551-21575686 "Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.2;kidney: 16.6" "Group enriched" "Detected in some" 9 "Excitatory neurons: 279.0;Inhibitory neurons: 175.8;Oligodendrocyte precursor cells: 323.2" "Cancer enhanced" "Detected in many" "melanoma: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "OE19: 28.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051535 Approved "Secreted in other tissues" NA NA 160000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA051535: AB_2681524" "unprognostic (1.73e-1)" "unprognostic (1.31e-1)" "unprognostic (7.29e-2)" "unprognostic (5.35e-4)" "unprognostic (3.78e-4)" "unprognostic (1.67e-2)" "unprognostic (3.91e-1)" "unprognostic (4.38e-2)" "unprognostic (4.65e-2)" "unprognostic (1.57e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (7.27e-3)" "unprognostic (4.23e-2)" "unprognostic (1.83e-1)" "unprognostic (2.29e-1)" 0.3 0.1 4.5 0.1 5.5 0.0 0.0 0.0 8.2 0.3 0.0 0.2 0.0 0.3 1.6 0.6 0.1 0.4 0.0 10.2 2.0 16.6 0.0 0.4 0.0 2.4 1.9 0.1 0.0 0.0 3.5 0.0 2.5 5.1 0.3 0.8 0.4 2.5 0.0 0.6 0.1 0.1 0.0 0.1 0.6 1.0 1.5 1.2 0.0 0.3 0.7 0.1 0.6 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 28.6 0.0 0.0 0.7 0.0 0.0 0.1 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 5.5 0.0 8.2 10.2 2.0 2.4 1.9 2.5 0.0 1.5 4.2 0.1 0.0 0.0 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.8 0.7 0.0 0.0 1.8 0.0 0.8 0.0 0.0 5.9 0.0 28.8 0.8 0.1 0.0 0.0 0.0 279.0 0.0 0.0 0.2 0.0 0.0 3.8 0.0 0.0 0.0 0.1 0.0 175.8 0.0 0.0 0.0 0.0 22.3 0.3 0.0 0.0 13.1 0.0 0.0 0.0 323.2 7.6 0.0 0.0 0.0 0.0 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.2 0.5 0.0 0.0 0.7 0.1 0.0 0.0 0.2 NELL2 NRP2 ENSG00000184613 "Neural EGFL like 2" Q99435 12 44508275-44921848 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.5;choroid plexus: 59.5;fallopian tube: 60.1;retina: 85.2" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 652.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 33.3" "Group enriched" "Detected in many" 15 "amygdala: 48.9;basal ganglia: 60.0;cerebral cortex: 105.5;hippocampal formation: 89.6;white matter: 42.0" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 70.4;naive CD8 T-cell: 111.1" "Lineage enriched" "Detected in many" 10 "T-cells: 111.1" "Cell line enhanced" "Detected in some" "AF22: 104.6;HEK 293: 27.5;NTERA-2: 41.2;SCLC-21H: 75.6;U-266/70: 27.5;U-266/84: 29.5;U-698: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035714, HPA035715" Uncertain Approved Vesicles "Secreted to blood" NA NA 6400000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA035714: AB_2674746, HPA035715: AB_10669602" "unprognostic (4.25e-3)" "unprognostic (4.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (7.18e-2)" "unprognostic (5.85e-2)" "unprognostic (2.59e-2)" "unprognostic (4.85e-2)" "unprognostic (2.80e-1)" "prognostic favorable (5.56e-4)" "unprognostic (1.19e-1)" "unprognostic (1.71e-5)" "unprognostic (8.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.60e-3)" "unprognostic (3.75e-2)" 4.6 16.9 48.9 10.9 60.0 7.3 1.9 1.3 105.5 23.1 59.5 2.0 26.3 2.2 0.4 1.2 60.1 1.9 0.4 89.6 4.5 1.2 1.0 5.0 20.7 0.0 0.0 0.8 0.9 0.2 34.6 0.3 0.0 27.2 2.1 85.2 1.4 2.0 0.3 13.4 15.3 2.8 0.0 6.2 2.9 3.0 0.8 8.7 6.5 0.6 15.7 4.1 4.2 42.0 0.3 0.1 104.6 3.5 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 8.3 12.4 0.0 0.0 0.2 25.3 0.2 0.0 0.0 27.5 0.4 8.7 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.1 1.6 0.2 0.4 0.0 0.4 0.2 0.4 41.2 0.0 14.0 0.2 12.7 0.2 0.0 0.0 75.6 1.8 0.0 0.4 0.0 1.3 0.1 0.7 0.0 0.4 3.8 0.1 2.1 27.5 29.5 40.3 0.2 0.2 0.4 0.2 0.2 0.0 5.0 0.1 24.9 0.2 30.3 52.9 0.1 0.1 70.4 111.1 0.5 11.0 0.1 0.1 0.4 26.7 48.9 60.0 1.3 105.5 89.6 4.5 0.0 0.0 0.0 0.0 0.8 42.0 0.3 0.0 1.3 48.0 1.0 1.1 0.0 0.0 5.7 35.4 0.4 0.6 0.5 2.8 6.2 0.0 33.3 0.1 2.5 5.8 0.0 0.0 0.4 0.7 0.8 0.7 0.0 0.0 652.4 0.2 0.3 3.7 0.0 0.3 0.0 49.4 0.0 0.0 0.1 1.7 108.4 0.9 0.0 0.0 1.5 1.0 0.0 0.4 0.0 18.7 1.3 7.9 1.0 74.4 16.5 0.4 0.4 0.4 0.5 0.3 18.5 0.2 21.9 58.3 0.0 4.1 4.6 1.9 4.2 0.2 1.1 0.1 23.4 0.1 2.9 0.1 NENF "CIR2, SCIRP10, SPUF" ENSG00000117691 "Neudesin neurotrophic factor" Q9UMX5 1 212432920-212446379 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 512.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026763, HPA028488" Uncertain "Secreted to blood" NA NA 4000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA026763: AB_1854379, HPA028488: AB_2672638" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (2.49e-2)" "unprognostic (7.24e-2)" "unprognostic (7.41e-3)" "unprognostic (3.80e-3)" "unprognostic (5.35e-2)" "unprognostic (1.70e-2)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (4.99e-3)" "prognostic unfavorable (1.54e-6)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (4.28e-1)" "unprognostic (2.28e-2)" 63.9 53.4 132.2 16.8 149.0 26.9 65.7 141.3 188.1 82.8 137.7 53.8 19.8 59.8 70.2 45.9 58.3 23.9 141.0 130.9 138.5 70.0 62.7 45.4 16.4 142.5 142.7 82.7 68.7 64.1 148.1 29.4 143.2 69.4 36.1 22.7 72.4 50.5 95.0 55.6 35.2 44.7 142.7 33.6 47.7 16.7 138.3 23.0 57.6 104.5 25.6 58.0 57.7 156.0 78.8 65.3 26.6 103.2 155.3 116.6 38.9 39.5 94.5 67.5 65.7 74.0 49.8 36.0 29.0 93.0 68.4 49.7 55.1 56.0 55.1 45.7 107.2 26.5 39.9 24.4 59.3 25.1 66.2 83.9 82.5 47.8 40.0 76.1 44.1 54.1 60.2 39.0 60.5 40.2 45.4 95.3 39.0 73.9 137.9 42.1 62.6 50.2 70.3 23.1 43.2 77.5 59.2 89.6 74.0 40.4 70.8 75.2 9.1 54.9 49.0 76.8 73.3 36.2 62.6 26.9 57.5 36.0 43.0 0.9 4.8 2.1 3.9 7.1 6.9 8.1 4.7 8.8 7.8 5.3 6.1 6.2 0.5 0.9 5.0 13.5 5.8 2.5 132.2 149.0 141.3 188.1 130.9 138.5 142.5 142.7 143.2 142.7 138.3 156.0 124.8 12.8 21.6 14.0 72.0 166.2 233.0 10.8 173.6 44.0 322.5 418.5 152.9 163.0 13.4 248.3 12.5 291.4 64.3 101.0 164.4 50.9 5.3 40.7 119.1 87.4 135.8 135.0 11.9 49.0 182.0 219.7 65.7 58.4 47.1 45.7 145.3 211.8 189.3 38.7 12.6 143.7 6.1 149.4 198.1 23.9 297.6 127.2 186.7 11.2 69.2 329.6 34.0 21.6 80.5 32.7 70.7 223.8 136.0 322.9 56.1 512.7 7.6 28.4 118.3 162.1 233.9 13.3 138.5 158.8 170.6 184.4 70.4 61.8 157.0 264.5 NETO1 "BCTL1, BTCL1" ENSG00000166342 "Neuropilin and tolloid like 1" Q8TDF5 18 72742314-72868146 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 21.9;retina: 34.6" "Group enriched" "Detected in some" 14 "Bipolar cells: 206.4;Excitatory neurons: 307.1;Inhibitory neurons: 345.9;Oligodendrocyte precursor cells: 172.4" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Group enriched" "Detected in many" 41 "amygdala: 6.6;basal ganglia: 12.4;cerebral cortex: 21.9;hippocampal formation: 17.5;white matter: 16.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MOLT-4: 21.9;REH: 20.6;RPMI-8226: 32.7;RT4: 24.7;SCLC-21H: 26.9;U-2 OS: 11.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064630 Approved "Golgi apparatus" "Secreted in brain" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA064630: AB_2685305" "unprognostic (4.02e-2)" "unprognostic (4.08e-3)" "unprognostic (2.75e-1)" "unprognostic (1.55e-2)" "unprognostic (6.04e-2)" "unprognostic (1.35e-5)" "unprognostic (4.05e-1)" "unprognostic (4.73e-2)" "unprognostic (3.09e-1)" "unprognostic (1.56e-1)" "unprognostic (6.63e-2)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (3.70e-2)" "unprognostic (3.35e-2)" "unprognostic (1.59e-1)" "unprognostic (9.13e-3)" 1.2 0.0 6.6 0.3 12.4 0.1 1.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 17.5 0.0 0.1 0.0 0.0 1.0 0.3 0.0 0.0 0.2 0.1 0.2 0.0 0.3 0.0 0.1 34.6 0.2 0.0 0.0 0.3 0.5 0.0 0.0 3.1 0.2 0.8 0.2 0.4 0.6 0.0 1.2 0.1 0.0 16.3 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 8.7 0.0 0.0 20.6 0.0 32.7 4.0 24.7 26.9 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 12.4 0.0 21.9 17.5 0.0 0.3 0.0 0.3 0.0 0.2 16.3 2.0 0.0 0.0 16.6 6.1 0.0 0.0 0.0 0.0 206.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 307.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 345.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 17.8 0.0 2.2 0.0 172.4 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.3 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NEU1 NEU ENSG00000204386 "Neuraminidase 1" Q99519 6 31857659-31862905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 3.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.0" "Cell line enhanced" "Detected in some" "GAMG: 5.4;U-266/84: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015634, HPA021506" Approved Supported "Vesicles,Cell Junctions" NA NA 180000 "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Vesicles "Cell Junctions" "HPA015634: AB_1854386, HPA021506: AB_1854385" "unprognostic (3.84e-2)" "unprognostic (7.47e-2)" "unprognostic (9.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-1)" "unprognostic (4.42e-3)" "unprognostic (1.38e-3)" "unprognostic (8.58e-3)" "unprognostic (7.49e-2)" "unprognostic (5.21e-2)" "unprognostic (4.44e-3)" "unprognostic (1.27e-1)" "unprognostic (2.70e-2)" "unprognostic (6.22e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (2.13e-3)" 23.9 57.2 0.7 0.4 0.8 0.0 22.4 2.5 1.2 21.2 1.2 25.1 0.7 19.5 0.0 14.9 16.8 1.0 22.5 0.7 0.6 43.7 29.9 28.9 0.3 0.8 0.5 20.3 35.9 0.3 33.0 0.2 0.8 26.5 0.0 1.6 38.6 0.0 21.3 20.1 24.3 0.1 0.3 25.3 29.8 8.2 1.0 0.0 31.8 0.0 0.0 23.2 16.2 1.7 0.3 0.2 0.8 1.4 1.8 0.4 0.7 0.2 0.2 0.3 0.3 1.5 0.6 0.7 0.4 0.1 5.4 0.3 2.2 0.0 0.4 2.5 0.3 0.6 0.9 1.2 1.4 0.9 1.8 1.0 0.2 1.4 0.7 0.2 0.6 0.9 1.1 1.2 0.5 0.3 0.6 0.0 0.6 0.5 0.4 0.9 0.4 0.9 1.0 0.4 0.7 0.4 0.2 0.3 0.7 0.9 0.9 0.5 0.7 1.1 0.8 0.7 0.6 3.7 9.6 0.9 1.7 0.4 0.4 1.3 0.3 0.4 0.2 0.3 0.1 0.2 0.2 0.1 0.2 0.6 0.2 0.3 3.0 0.3 0.2 0.3 0.2 0.1 0.7 0.8 2.5 1.2 0.7 0.6 0.8 0.5 0.8 0.3 1.0 1.7 65.7 25.6 46.3 5.2 57.0 34.3 48.5 45.0 39.9 26.4 87.7 55.8 29.0 51.5 54.8 47.8 25.0 62.8 100.5 83.7 9.8 114.2 0.8 29.3 53.5 42.8 113.5 4.6 6.3 59.6 57.8 73.8 32.6 60.8 67.9 17.4 30.7 34.5 170.9 10.1 7.6 39.9 79.3 63.0 65.9 1.4 27.7 93.0 71.2 9.4 25.8 48.8 9.2 5.0 4.0 34.4 88.1 23.3 81.7 89.0 115.0 59.9 29.2 32.7 26.3 60.8 43.7 5.4 10.0 29.3 41.6 197.0 81.7 40.3 41.1 34.6 NEU4 ENSG00000204099 "Neuraminidase 4" Q8WWR8 2 241809065-241817413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 75.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 74.6;Enteroendocrine cells: 34.4;Hepatocytes: 124.4;Intestinal goblet cells: 38.5;Oligodendrocyte precursor cells: 50.3;Paneth cells: 58.0;Proximal enterocytes: 76.0;Undifferentiated cells: 38.4" "Group enriched" "Detected in some" 7 "colorectal cancer: 2.3;glioma: 6.0;liver cancer: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "Hep G2: 57.7;HMC-1: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037394 Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA037394: AB_2675455" "unprognostic (1.50e-1)" "unprognostic (2.39e-3)" "unprognostic (1.85e-1)" "unprognostic (3.68e-4)" "unprognostic (3.76e-2)" "unprognostic (1.57e-1)" "unprognostic (8.70e-2)" "unprognostic (8.62e-2)" "unprognostic (1.74e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-2)" "unprognostic (2.92e-1)" "unprognostic (8.11e-4)" "unprognostic (2.00e-2)" "unprognostic (3.82e-1)" "unprognostic (6.64e-3)" "unprognostic (1.55e-2)" 0.9 0.2 2.3 0.1 2.5 3.5 0.2 2.2 4.4 0.5 0.6 15.5 10.7 0.2 0.0 0.0 0.7 0.4 0.3 2.1 2.5 1.8 75.8 0.4 0.0 5.0 2.8 0.3 0.1 0.0 1.1 0.0 2.7 0.4 2.2 0.1 0.8 0.0 9.0 0.1 9.2 0.0 2.6 0.3 0.1 0.7 2.7 0.0 0.3 0.8 0.0 0.1 0.1 2.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 57.7 0.0 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.5 2.2 4.4 2.1 2.5 5.0 2.8 2.7 2.6 2.7 2.9 0.2 0.0 0.0 1.0 0.5 0.0 0.0 0.3 0.0 0.7 0.0 0.1 0.6 1.5 0.7 1.8 0.0 0.0 1.1 74.6 3.9 0.0 0.1 0.0 0.1 0.3 34.4 0.0 0.4 0.0 0.0 0.2 0.5 0.0 1.3 0.1 1.1 124.4 1.5 0.0 0.4 38.5 2.0 4.2 0.7 0.2 0.6 4.0 0.0 0.0 0.0 26.2 0.0 50.3 0.1 0.0 58.0 0.7 0.4 0.0 76.0 23.6 0.2 1.3 0.0 3.6 0.4 0.5 0.5 0.0 0.0 0.0 1.3 0.0 38.4 0.1 NFASC "FLJ46866, KIAA0756, NF, NRCAML" ENSG00000163531 Neurofascin O94856 1 204828651-205022822 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 151.0;Excitatory neurons: 148.4;Horizontal cells: 220.4;Inhibitory neurons: 139.0;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 226.6;Rod photoreceptor cells: 195.5" "Cancer enriched" "Detected in many" 5 "glioma: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 27.6;fHDF/TERT166: 50.3;hTERT-RPE1: 24.0;SCLC-21H: 22.8;U-138 MG: 62.7;U-87 MG: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008832 Enhanced NA NA 2200000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "HPA008832: AB_1854411" "unprognostic (1.71e-1)" "unprognostic (1.07e-1)" "unprognostic (2.62e-1)" "unprognostic (3.39e-2)" "unprognostic (6.65e-2)" "unprognostic (1.18e-2)" "unprognostic (3.71e-3)" "unprognostic (3.37e-1)" "unprognostic (6.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.21e-5)" "unprognostic (3.76e-1)" "prognostic unfavorable (2.93e-5)" "unprognostic (1.56e-3)" "unprognostic (1.91e-1)" "unprognostic (6.90e-2)" "unprognostic (5.26e-3)" 5.2 7.5 7.8 3.7 31.5 0.1 3.2 8.4 15.2 5.0 0.0 8.6 4.5 8.3 9.0 10.0 12.1 5.9 15.3 10.7 5.6 9.8 1.9 5.0 2.3 13.1 14.1 10.1 5.9 1.0 5.6 10.6 7.8 7.5 5.9 22.6 2.1 16.3 3.0 4.3 5.0 14.2 3.9 6.5 4.4 1.5 35.6 0.6 2.9 3.8 2.9 9.4 7.7 50.1 0.0 0.1 3.1 0.1 0.4 1.0 0.1 27.6 0.0 19.9 5.9 0.2 0.1 0.0 0.1 50.3 18.5 13.4 0.6 0.8 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 12.7 0.7 24.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 7.0 0.9 0.3 0.0 2.3 0.0 0.0 0.0 22.8 1.3 0.0 1.5 0.0 2.0 0.3 0.0 0.0 62.7 13.5 0.1 0.0 0.0 0.0 0.0 31.3 0.0 16.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 31.5 8.4 15.2 10.7 5.6 13.1 14.1 7.8 3.9 35.6 50.1 2.5 0.0 0.6 64.3 0.0 2.2 1.5 1.9 0.6 151.0 1.7 10.5 23.9 1.5 1.5 0.0 12.5 0.5 0.0 0.3 0.0 0.2 7.3 0.5 0.4 7.6 37.8 0.0 148.4 0.0 0.5 14.2 1.1 0.1 0.0 0.1 3.3 1.7 0.4 220.4 139.0 6.0 0.0 0.6 1.9 17.9 6.5 0.4 1.8 15.0 0.0 14.2 0.0 87.9 226.6 0.5 0.5 5.7 0.0 1.1 0.0 1.5 5.9 195.5 52.6 2.3 49.9 1.7 3.9 5.5 4.7 0.7 0.3 0.7 1.0 0.8 NFE2L1 "FLJ00380, LCR-F1, NRF1, TCF11" ENSG00000082641 "Nuclear factor, erythroid 2 like 1" Q14494 17 48048329-48061545 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1357.5;tongue: 858.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 303.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063384, HPA065424" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA063384: AB_2684998, HPA065424: AB_2685488" "unprognostic (3.19e-1)" "unprognostic (2.41e-1)" "unprognostic (5.44e-2)" "prognostic favorable (8.20e-5)" "unprognostic (5.25e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (5.20e-2)" "unprognostic (5.58e-2)" "unprognostic (9.30e-2)" "unprognostic (2.61e-1)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "prognostic favorable (5.79e-6)" "unprognostic (2.20e-1)" "unprognostic (4.09e-2)" "unprognostic (6.19e-3)" "unprognostic (2.01e-2)" 154.3 130.5 109.3 75.0 99.3 31.1 91.1 101.6 98.3 103.5 225.0 107.6 106.0 149.4 88.2 126.0 130.6 97.3 430.8 112.4 146.3 159.6 104.0 83.3 63.8 135.0 131.1 148.8 65.2 115.2 82.5 100.6 131.0 95.7 80.1 67.1 92.1 123.5 1357.5 121.1 113.3 141.0 116.3 113.0 79.0 69.3 126.8 62.3 132.6 858.4 59.2 89.7 86.3 138.2 122.2 265.4 172.0 147.4 349.8 168.2 128.6 193.7 269.2 135.1 149.8 327.6 137.6 139.8 379.2 244.6 175.2 245.5 122.5 154.5 144.7 239.9 104.1 78.8 181.0 111.1 418.6 178.0 122.1 232.6 380.7 246.7 267.2 228.7 214.6 93.5 142.5 377.4 169.4 103.3 115.5 56.0 113.0 110.0 101.4 80.1 241.8 136.4 150.0 181.0 105.8 160.2 132.4 89.0 272.4 222.5 175.7 120.5 291.2 324.2 141.4 112.3 197.4 626.6 460.1 134.1 310.4 73.6 191.3 14.2 11.8 4.0 3.4 6.5 2.0 5.2 3.1 3.5 2.6 4.9 2.4 2.7 26.1 3.0 8.7 12.9 1.2 1.3 109.3 99.3 101.6 98.3 112.4 146.3 135.0 131.1 131.0 116.3 126.8 138.2 60.1 57.7 49.4 25.1 15.8 55.7 19.3 45.0 34.1 68.8 39.2 33.8 303.1 50.1 34.4 77.3 35.5 22.7 14.7 150.7 25.4 41.3 8.1 57.9 92.0 66.3 30.1 11.6 24.5 36.2 21.5 47.9 27.5 58.8 28.4 89.3 80.3 126.7 36.0 72.3 28.0 51.5 38.7 32.8 18.9 10.6 102.2 23.8 21.4 20.6 31.5 25.4 15.5 9.0 14.4 51.8 64.8 83.8 17.4 33.8 100.3 39.1 49.5 34.8 59.2 39.3 53.8 30.0 35.5 25.9 48.4 22.3 14.2 44.6 49.4 24.4 NFE2L3 Nrf3 ENSG00000050344 "Nuclear factor, erythroid 2 like 3" Q9Y4A8 7 26152198-26187137 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7;placenta: 34.4" "Group enriched" "Detected in many" 14 "Cytotrophoblasts: 305.9;Syncytiotrophoblasts: 698.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 133.5;NTERA-2: 113.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055889 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Vesicles" "HPA055889: AB_2682958" "unprognostic (4.99e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-3)" "unprognostic (5.37e-2)" "unprognostic (8.41e-2)" "unprognostic (4.00e-3)" "unprognostic (7.29e-3)" "unprognostic (1.87e-1)" "unprognostic (2.12e-1)" "unprognostic (9.88e-2)" "prognostic unfavorable (6.62e-5)" "unprognostic (2.32e-1)" "prognostic unfavorable (7.58e-12)" "prognostic favorable (2.14e-4)" "unprognostic (2.40e-1)" "unprognostic (8.25e-2)" "unprognostic (4.13e-3)" 3.6 3.1 4.2 10.6 7.3 2.5 2.2 19.5 19.7 1.5 2.3 6.3 8.0 2.2 0.2 2.4 1.6 4.3 1.4 6.3 4.8 2.5 1.6 4.8 8.0 7.0 4.6 1.1 4.8 0.4 1.3 34.4 7.2 1.4 4.8 5.1 3.2 0.6 2.7 7.3 5.7 1.0 5.1 7.6 7.3 1.4 6.3 5.9 1.0 0.2 7.0 4.8 1.5 10.8 40.9 3.5 1.6 4.0 0.0 0.0 133.5 7.9 15.2 15.0 27.3 26.2 68.8 3.0 51.2 0.8 57.5 8.6 6.0 13.4 33.7 27.9 8.5 5.7 7.0 19.8 10.5 5.0 52.3 1.3 1.6 6.2 2.3 22.4 35.0 11.3 8.6 69.9 3.0 5.5 3.5 8.8 113.9 11.1 13.9 5.0 0.4 20.5 20.5 40.5 12.3 14.7 0.2 3.2 1.2 37.5 1.9 3.0 76.0 1.4 2.3 0.6 32.6 42.0 72.2 3.4 0.2 17.5 53.1 0.0 0.2 0.0 0.1 0.2 0.3 0.2 0.4 0.2 0.6 0.2 0.2 0.1 0.1 0.2 0.0 0.2 0.6 0.1 4.2 7.3 19.5 19.7 6.3 4.8 7.0 4.6 7.2 5.1 6.3 10.8 14.6 6.4 2.8 3.9 4.6 1.8 4.2 12.7 5.2 1.4 3.1 2.3 1.9 14.3 6.9 11.0 0.0 305.9 1.6 6.1 0.0 13.0 1.0 6.1 1.8 7.6 1.2 12.0 3.8 5.3 33.9 2.8 14.3 6.4 27.9 35.2 2.2 0.3 24.3 0.0 4.4 6.6 12.2 15.6 17.2 0.3 0.0 16.7 1.8 2.8 11.1 1.1 4.1 1.5 11.6 15.6 4.1 0.0 18.2 10.4 2.7 0.5 8.9 1.9 0.0 2.9 2.7 0.6 7.1 5.5 1.6 698.6 9.0 4.8 9.8 6.7 NFIA "KIAA1439, NFI-L" ENSG00000162599 "Nuclear factor I A" Q12857 1 60865259-61462788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.9" "Cell type enhanced" "Detected in all" "Astrocytes: 777.3;Oligodendrocyte precursor cells: 606.7;Peritubular cells: 438.5;Skeletal myocytes: 513.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006111, HPA008884" Enhanced Enhanced Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA006111: AB_1854422, HPA008884: AB_1854421" "unprognostic (1.50e-3)" "unprognostic (1.32e-1)" "unprognostic (2.06e-1)" "unprognostic (1.05e-1)" "unprognostic (3.44e-2)" "prognostic favorable (7.30e-4)" "unprognostic (2.55e-1)" "unprognostic (1.22e-2)" "unprognostic (9.12e-2)" "unprognostic (9.38e-2)" "unprognostic (2.85e-2)" "unprognostic (5.20e-2)" "prognostic favorable (7.01e-4)" "unprognostic (2.11e-1)" "unprognostic (1.20e-1)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.03e-4)" 23.0 12.4 28.4 5.2 37.7 10.0 15.1 75.9 24.6 18.3 31.8 14.2 7.2 8.9 11.7 18.8 15.6 14.3 16.9 28.4 31.3 10.8 40.5 8.4 5.1 51.5 33.4 15.7 13.5 10.9 5.4 4.3 34.9 15.0 9.1 4.2 17.5 11.6 13.8 8.7 6.4 13.2 37.3 9.4 9.7 5.8 33.6 8.6 27.4 15.8 6.8 13.8 10.3 27.1 5.0 6.8 1.0 74.2 31.8 20.2 0.2 1.6 5.1 1.6 2.4 0.4 4.8 10.9 4.8 2.7 0.7 7.2 3.1 15.4 0.9 23.4 6.6 0.4 15.2 4.8 7.3 1.2 1.8 25.7 14.9 6.8 27.6 5.5 19.1 3.0 5.1 16.9 1.5 3.6 0.3 0.3 2.9 6.9 6.6 1.1 6.9 18.2 4.3 13.1 4.8 5.7 4.1 28.2 10.3 0.8 30.2 0.5 15.5 1.3 8.5 15.2 3.1 1.2 3.1 0.1 1.7 0.2 1.7 3.2 2.7 1.5 1.9 1.9 2.9 0.6 2.3 3.0 1.3 0.3 2.2 2.7 0.1 0.5 2.5 1.0 0.1 1.8 28.4 37.7 75.9 24.6 28.4 31.3 51.5 33.4 34.9 37.3 33.6 27.1 232.1 35.3 44.7 777.3 4.4 85.0 68.8 72.1 220.9 42.6 140.7 107.4 192.9 148.7 68.1 47.8 2.1 5.7 8.1 28.4 27.4 38.0 28.9 85.8 69.8 132.7 25.2 163.7 142.3 47.8 1.1 265.6 30.5 68.2 27.3 11.6 197.0 304.5 14.8 42.1 125.7 46.8 36.7 60.8 42.6 26.4 408.8 19.2 46.2 259.5 14.9 150.2 5.2 606.7 431.3 20.8 37.6 438.5 8.0 53.0 19.1 109.9 82.6 6.9 144.7 513.1 133.7 5.0 13.5 148.4 76.3 1.6 15.0 34.9 69.7 57.1 NGEF ARHGEF27 ENSG00000066248 "Neuronal guanine nucleotide exchange factor" Q8N5V2 2 232878701-233013256 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 56.2;brain: 129.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.0;Excitatory neurons: 105.9;Proximal enterocytes: 66.7" "Cancer enhanced" "Detected in many" "testis cancer: 22.5" "Region enhanced" "Detected in many" "basal ganglia: 129.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 53.9;HDLM-2: 45.3;HeLa: 21.6;PC-3: 57.0;T-47d: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 167.6;cerebral cortex: 133.8;hippocampal formation: 73.0" HPA008160 Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA008160: AB_1854450" "unprognostic (3.92e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-3)" "unprognostic (1.66e-1)" "unprognostic (5.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.15e-1)" "unprognostic (2.39e-3)" "unprognostic (5.41e-3)" "unprognostic (2.58e-1)" "unprognostic (6.94e-3)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (2.80e-2)" "unprognostic (2.74e-1)" 1.1 56.2 16.3 2.2 129.6 0.1 1.9 0.0 59.4 4.1 0.0 14.2 42.7 5.0 4.1 10.3 4.8 3.1 2.2 19.8 0.0 7.0 35.5 0.7 0.2 0.0 0.0 2.0 6.0 11.9 2.7 0.3 0.0 1.8 10.5 1.4 2.0 0.7 0.9 30.3 31.3 6.7 0.0 0.4 10.7 3.7 0.2 0.0 0.9 0.7 0.3 1.8 5.2 29.4 53.9 15.4 0.6 0.2 0.2 8.2 0.9 0.9 0.1 0.4 0.0 0.7 5.2 0.0 15.2 10.9 5.5 6.9 11.6 3.0 0.4 45.3 3.8 0.1 21.6 16.7 0.2 0.0 0.3 0.0 0.2 3.5 0.6 0.2 1.9 0.2 0.2 0.2 0.5 4.0 0.0 0.1 1.3 0.2 57.0 0.0 0.0 0.1 1.0 1.4 1.9 0.4 6.6 3.3 0.1 2.0 32.2 0.4 0.0 0.5 4.5 0.3 1.0 0.5 0.2 0.0 3.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 129.6 0.0 59.4 19.8 0.0 0.0 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 10.4 0.0 9.9 1.2 1.2 2.8 0.3 2.1 1.4 2.4 4.3 0.5 0.0 0.0 0.1 0.0 38.0 0.0 3.9 0.7 9.1 0.9 0.4 4.9 0.0 105.9 10.5 0.3 0.7 17.3 2.0 0.0 0.3 0.4 20.4 0.1 1.7 12.8 14.6 0.0 0.3 0.6 2.0 0.0 0.3 1.8 6.5 0.0 5.5 0.0 4.5 6.0 12.1 23.5 1.2 0.1 0.5 66.7 9.8 2.5 0.2 0.0 0.2 0.3 1.1 0.8 3.8 7.5 0.0 0.2 0.5 20.2 1.1 NGF NGFB ENSG00000134259 "Nerve growth factor" P01138 1 115285904-115338770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 20.8;ovary: 18.9" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 15.7;Leydig cells: 29.2;Sertoli cells: 118.3;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in many" "renal cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 87.9;BJ hTERT+ SV40 Large T+: 30.1;GAMG: 46.2;hTEC/SVTERT24-B: 29.8;hTERT-RPE1: 49.0;U-2197: 60.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted in other tissues" NA NA 40000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "unprognostic (7.55e-2)" "unprognostic (2.66e-2)" "unprognostic (1.53e-3)" "unprognostic (8.85e-2)" "unprognostic (4.12e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (5.30e-2)" "unprognostic (8.73e-3)" "unprognostic (4.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.08e-7)" "unprognostic (1.15e-3)" "unprognostic (2.13e-1)" "unprognostic (7.99e-3)" "unprognostic (1.62e-4)" 13.9 2.5 1.7 1.6 1.7 0.0 4.0 1.3 2.1 7.1 2.1 5.0 0.1 8.8 1.4 1.1 13.2 1.7 20.8 1.6 2.2 6.4 4.0 1.6 0.5 1.9 1.7 18.9 0.8 0.4 2.7 1.1 1.9 2.6 0.6 0.1 2.1 1.0 0.9 0.9 2.1 4.0 1.4 3.7 2.1 1.1 1.9 0.2 3.3 1.1 0.1 5.5 5.0 1.6 0.0 0.3 0.0 0.0 1.8 0.1 0.0 87.9 9.9 30.1 21.9 0.0 0.0 0.0 1.9 21.1 46.2 3.6 0.0 0.6 13.8 0.0 0.2 0.0 0.6 0.0 12.1 0.0 0.0 0.1 0.6 29.8 21.6 49.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 3.0 0.0 1.3 0.0 1.2 0.0 0.0 0.0 1.1 0.3 1.6 0.6 0.0 3.9 0.0 0.0 0.8 1.8 3.7 60.0 3.5 0.0 0.0 0.0 3.6 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.7 1.3 2.1 1.6 2.2 1.9 1.7 1.9 1.4 1.9 1.6 0.4 0.0 0.0 0.3 0.0 3.1 0.5 3.9 0.0 0.0 0.1 1.5 0.7 1.5 0.2 0.0 0.0 3.0 0.0 0.0 0.0 5.6 0.2 0.2 0.8 0.8 0.0 0.0 0.3 0.0 1.3 7.3 0.0 0.3 0.0 0.0 4.2 0.0 0.1 0.0 15.7 0.0 2.0 0.0 1.7 0.4 29.2 0.2 1.8 1.9 0.0 0.0 0.0 12.1 0.5 0.1 0.0 6.0 0.0 0.6 0.0 0.0 0.1 0.0 118.3 0.8 51.6 0.3 1.0 0.0 2.3 2.5 0.6 0.0 0.0 0.3 NGLY1 "FLJ11005, PNG-1, PNG1" ENSG00000151092 "N-glycanase 1" Q96IV0 3 25718944-25790039 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 594.1;Late spermatids: 963.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036825 Approved "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA036825: AB_10672231" "unprognostic (3.65e-2)" "unprognostic (8.65e-2)" "prognostic favorable (1.17e-5)" "unprognostic (2.96e-2)" "unprognostic (1.72e-2)" "unprognostic (1.59e-2)" "prognostic unfavorable (1.96e-6)" "unprognostic (2.20e-1)" "unprognostic (2.34e-1)" "unprognostic (3.73e-3)" "unprognostic (2.55e-1)" "unprognostic (4.23e-2)" "unprognostic (4.92e-3)" "unprognostic (1.07e-2)" "unprognostic (2.47e-1)" "unprognostic (9.08e-2)" "unprognostic (1.89e-2)" 10.8 13.7 6.9 15.1 7.1 25.6 15.6 10.0 9.2 12.3 10.5 17.9 14.6 9.7 16.2 12.3 11.5 9.8 16.1 7.5 8.0 17.8 22.4 11.4 25.9 8.1 9.2 11.8 15.9 11.6 5.9 11.9 8.2 14.2 20.6 13.5 14.9 9.9 49.5 9.8 15.4 12.1 6.7 15.5 15.3 55.8 9.1 27.4 13.6 38.1 25.3 16.1 9.9 8.6 27.6 24.2 12.8 27.4 23.5 22.7 15.0 21.6 20.4 29.7 25.5 14.8 20.9 64.3 24.5 19.9 28.3 12.1 45.5 14.0 39.2 27.8 18.5 49.9 15.1 24.8 29.0 48.3 25.7 20.3 17.5 33.6 31.5 32.2 31.3 32.8 47.9 49.1 30.3 11.7 60.7 26.8 17.4 33.2 43.5 54.2 16.5 54.6 27.1 31.1 8.3 9.5 35.1 33.3 23.3 24.0 31.1 40.6 15.7 15.5 20.1 27.5 29.9 60.4 60.7 48.8 25.1 52.8 18.1 48.8 19.7 27.8 22.9 19.4 26.0 42.2 23.2 23.5 31.6 33.4 21.8 23.6 18.3 45.0 16.0 65.1 19.0 20.7 6.9 7.1 10.0 9.2 7.5 8.0 8.1 9.2 8.2 6.7 9.1 8.6 24.3 19.2 17.3 34.0 84.1 12.6 23.7 25.0 16.5 22.3 19.8 16.8 30.3 27.1 21.4 5.5 12.5 40.5 74.7 25.0 35.2 30.6 594.1 20.0 19.4 20.9 7.2 26.9 51.7 44.2 31.7 19.2 17.3 19.2 20.8 77.7 17.5 25.1 23.4 11.8 64.2 29.3 14.2 22.2 63.6 963.6 14.9 33.6 24.9 31.9 30.0 20.7 45.3 54.3 59.4 27.2 27.3 15.8 87.1 27.8 26.0 38.2 25.2 22.7 0.0 26.0 17.9 105.7 52.7 18.8 13.8 56.6 41.1 26.3 30.3 20.6 NGRN DSC92 ENSG00000182768 "Neugrin, neurite outgrowth associated" Q9NPE2 15 90265659-90275778 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 385.3;skeletal muscle: 376.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041367, HPA076267" Approved Supported "Nucleoplasm,Cytokinetic bridge,Mitochondria" "Intracellular and membrane" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" Mitochondria "Nucleoplasm, Cytokinetic bridge" "HPA041367: AB_10796668, HPA076267: " "unprognostic (2.82e-1)" "unprognostic (1.04e-2)" "unprognostic (1.66e-3)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (3.19e-2)" "unprognostic (2.94e-2)" "unprognostic (5.00e-2)" "unprognostic (7.78e-2)" "unprognostic (1.93e-2)" "unprognostic (5.22e-2)" "unprognostic (7.22e-2)" "unprognostic (3.31e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.68e-3)" "unprognostic (3.21e-1)" 61.0 91.8 322.8 32.9 334.0 31.7 61.4 312.4 385.3 68.8 312.1 47.0 39.7 63.4 98.3 51.7 65.3 47.1 133.0 332.8 329.8 71.7 59.1 50.3 31.8 316.3 322.1 67.8 46.4 87.6 3.0 46.4 318.1 80.1 51.1 157.0 46.3 88.9 376.8 32.6 35.6 74.6 324.8 37.0 41.5 54.2 334.5 39.6 74.0 291.8 37.4 69.2 2.7 320.9 62.1 127.8 151.7 99.7 138.4 63.9 70.4 100.7 88.4 110.5 94.0 133.2 90.5 38.4 113.8 108.9 110.2 118.2 120.3 64.7 121.5 42.6 104.6 61.0 88.4 110.6 117.7 44.5 36.1 83.4 183.3 60.8 132.9 83.7 79.5 45.7 105.0 64.7 112.8 106.5 35.9 53.5 152.7 198.8 55.0 65.6 72.8 63.1 109.8 168.3 145.8 117.0 107.1 90.1 239.1 149.1 141.9 82.6 64.6 138.3 92.3 85.7 161.7 96.9 268.2 66.4 76.8 90.1 106.4 66.4 62.1 99.0 87.2 65.2 109.9 107.7 106.1 101.9 59.2 105.7 122.6 106.8 23.4 86.7 76.0 62.8 133.5 108.0 322.8 334.0 312.4 385.3 332.8 329.8 316.3 322.1 318.1 324.8 334.5 320.9 10.8 19.2 27.4 21.5 26.2 7.1 10.6 3.7 75.1 10.4 9.1 5.8 10.1 1.5 21.6 5.5 10.4 5.9 5.0 12.1 5.9 33.6 1.9 16.2 14.6 15.8 26.5 12.0 58.3 23.4 4.5 23.0 30.1 9.4 20.3 5.5 7.5 3.8 4.2 16.8 54.0 14.4 4.1 3.8 3.6 4.0 9.0 8.4 8.8 16.9 11.6 15.1 0.0 12.5 22.2 29.9 20.0 8.6 25.0 9.2 12.6 7.8 59.8 11.2 13.1 10.5 19.6 5.2 4.3 55.2 5.1 6.7 19.9 5.7 15.4 8.7 NHLRC2 "DKFZp779F115, FLJ20147, FLJ25621, FLJ33312, MGC45492" ENSG00000196865 "NHL repeat containing 2" Q8NBF2 10 113854661-113917194 "Disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038493, HPA057564" Approved Approved Nucleoplasm NA NA 120000 "Cluster 14: Monocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA038493: AB_10672519, HPA057564: AB_2683469" "unprognostic (7.09e-2)" "unprognostic (7.33e-2)" "unprognostic (3.00e-1)" "unprognostic (4.74e-2)" "unprognostic (5.15e-2)" "unprognostic (1.03e-1)" "unprognostic (9.70e-2)" "unprognostic (1.66e-1)" "unprognostic (3.49e-1)" "unprognostic (1.36e-1)" "unprognostic (4.88e-2)" "unprognostic (8.98e-2)" "unprognostic (1.05e-1)" "unprognostic (8.99e-2)" "unprognostic (2.52e-1)" "unprognostic (8.60e-2)" "unprognostic (1.68e-2)" 5.9 5.6 4.4 4.9 5.1 4.2 6.2 5.8 5.2 7.0 7.6 6.5 5.4 6.2 6.9 4.7 5.7 4.1 16.5 3.5 4.3 5.4 8.7 6.6 5.9 5.1 4.8 7.2 7.9 10.5 5.3 6.4 5.1 8.8 5.8 10.1 6.7 4.8 10.6 7.0 6.2 5.2 4.2 7.2 6.4 3.8 4.6 4.6 7.6 7.5 5.5 6.2 6.2 6.0 10.8 6.8 13.1 10.8 4.7 8.4 8.3 7.4 8.8 6.3 6.9 4.7 10.3 5.8 5.2 7.5 5.5 9.4 10.8 6.1 10.7 7.0 5.4 6.2 5.7 6.7 7.1 8.9 6.8 5.8 7.4 7.0 14.4 12.2 7.7 4.1 7.4 6.5 8.6 5.0 5.1 6.9 3.9 6.6 3.4 4.7 18.8 3.4 7.8 5.9 3.4 6.9 5.8 7.3 9.1 6.1 5.3 6.6 9.9 7.5 7.6 4.8 11.3 4.4 2.3 5.7 6.2 14.0 5.1 0.9 0.5 0.7 0.6 0.4 0.6 0.6 0.4 0.7 0.6 0.6 0.4 0.5 0.3 0.6 0.9 0.8 0.5 0.3 4.4 5.1 5.8 5.2 3.5 4.3 5.1 4.8 5.1 4.2 4.6 6.0 22.4 19.2 21.3 40.5 13.7 7.9 13.1 8.9 11.4 20.8 15.2 9.7 74.4 18.6 18.8 36.8 14.6 16.8 8.3 8.5 7.9 10.9 5.4 15.6 24.1 19.4 10.3 27.6 45.5 12.3 12.9 19.3 16.3 14.4 10.8 23.3 19.2 28.2 10.1 28.6 34.7 15.8 10.2 17.6 6.7 8.6 18.0 13.7 7.2 44.0 13.2 20.6 13.4 58.3 55.2 11.1 15.4 26.4 9.1 17.3 12.4 11.8 8.9 25.7 65.7 29.1 19.1 16.0 11.4 9.9 8.4 18.2 10.9 18.7 12.3 14.1 NHLRC3 ENSG00000188811 "NHL repeat containing 3" Q5JS37 13 39038306-39050109 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013738 Uncertain "Secreted to blood" NA NA 310000 "Cluster 27: Non-specific - Gene expression" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "HPA013738: AB_1854455" "unprognostic (7.92e-2)" "unprognostic (3.51e-2)" "unprognostic (5.96e-2)" "unprognostic (3.90e-1)" "unprognostic (2.92e-2)" "unprognostic (1.22e-1)" "unprognostic (2.99e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-1)" "unprognostic (8.88e-2)" "unprognostic (2.28e-2)" "unprognostic (4.83e-2)" "unprognostic (3.21e-1)" "unprognostic (1.58e-2)" "unprognostic (2.99e-2)" "unprognostic (1.66e-1)" "unprognostic (7.81e-2)" 18.5 12.0 7.8 10.9 8.6 7.4 15.2 7.6 10.5 12.1 9.7 12.9 11.6 13.5 20.6 7.4 10.7 13.0 10.2 7.9 8.5 16.7 25.9 13.9 14.3 10.1 8.1 15.8 13.4 8.4 11.4 19.4 9.5 11.0 16.6 12.9 12.2 9.8 10.8 12.0 12.3 11.8 8.6 16.1 16.7 8.7 8.5 8.1 16.9 10.4 12.0 10.1 9.8 10.4 5.1 3.1 13.5 6.5 15.4 16.0 20.9 7.8 9.7 8.2 10.9 9.8 22.6 13.9 14.5 5.2 10.3 10.5 5.4 4.5 7.1 20.3 5.8 11.1 6.9 11.2 9.8 11.1 15.8 13.0 5.8 5.7 5.5 12.3 5.2 11.2 4.0 16.9 7.6 3.8 8.7 17.2 3.7 11.8 3.2 9.2 36.2 7.8 12.6 10.1 3.1 5.6 5.0 6.9 18.4 7.5 9.0 17.5 6.0 11.2 5.4 14.7 8.3 13.5 12.3 5.5 14.9 11.9 8.2 1.5 6.8 0.8 4.5 6.9 5.0 4.1 3.2 3.7 6.0 3.0 3.3 4.8 0.6 4.5 6.8 5.4 4.1 3.7 7.8 8.6 7.6 10.5 7.9 8.5 10.1 8.1 9.5 8.6 8.5 10.4 20.6 12.8 20.2 22.9 36.7 8.4 16.9 40.8 15.9 70.8 22.2 13.5 13.0 18.6 35.8 35.0 56.3 78.4 52.5 22.5 9.8 21.0 6.7 14.1 25.3 22.4 13.8 23.3 37.4 16.5 14.9 21.8 17.9 14.6 15.8 76.7 42.5 34.5 43.6 79.1 45.8 28.6 42.7 57.6 27.0 4.6 61.2 35.2 17.8 27.2 47.7 33.5 102.0 40.2 131.7 17.2 25.0 41.8 30.7 10.2 34.8 16.3 32.1 93.1 59.2 14.2 18.7 51.1 41.0 9.0 8.9 24.2 30.5 50.2 28.4 11.7 NID1 "entactin, NID" ENSG00000116962 "Nidogen 1" P14543 1 235975830-236065109 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 230.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 362.9;Fibroblasts: 137.6;Hepatic stellate cells: 191.3;Leydig cells: 177.3;Peritubular cells: 125.6;Sertoli cells: 243.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 5.7;intermediate monocyte: 11.2;myeloid DC: 4.4;non-classical monocyte: 7.3" "Group enriched" "Detected in many" 18 "dendritic cells: 4.4;monocytes: 11.2" "Cell line enhanced" "Detected in many" "ASC diff: 1569.3;ASC TERT1: 726.8;HSkMC: 619.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010044 Approved "Secreted to extracellular matrix" NA NA 150000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "CAB010044: AB_2153287" "unprognostic (1.17e-1)" "unprognostic (2.23e-3)" "unprognostic (3.24e-1)" "unprognostic (2.35e-1)" "unprognostic (4.03e-1)" "unprognostic (2.79e-2)" "unprognostic (2.44e-3)" "unprognostic (1.42e-2)" "unprognostic (7.88e-2)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (5.38e-8)" "unprognostic (3.64e-3)" "unprognostic (1.35e-1)" "unprognostic (7.36e-2)" "unprognostic (3.72e-3)" 110.0 35.5 4.1 30.5 6.8 2.6 88.9 3.4 7.4 78.9 8.8 95.9 21.7 87.6 21.3 26.8 88.1 66.2 53.7 3.8 4.3 28.4 76.9 56.4 12.3 4.2 4.0 77.7 18.3 12.6 10.4 230.9 3.9 33.1 21.3 2.0 17.3 40.2 25.1 24.6 61.0 79.8 3.9 38.0 67.0 6.2 5.3 5.4 27.6 26.9 6.1 62.9 53.4 3.8 1.2 5.3 55.3 0.1 1569.3 726.8 106.2 128.1 105.3 78.0 50.7 30.5 39.8 0.0 25.0 191.2 21.3 4.5 36.3 0.4 45.2 0.2 61.3 8.1 5.9 46.3 295.6 0.0 0.7 619.5 5.3 38.2 1.5 30.3 165.7 0.0 0.0 0.0 26.9 0.0 0.1 0.3 56.9 0.0 6.7 0.0 0.1 0.1 0.0 16.6 0.3 47.0 1.0 0.0 10.2 21.3 0.1 52.1 146.5 67.5 44.8 0.1 57.4 0.1 0.0 0.1 0.8 0.0 105.4 0.2 5.7 0.0 0.0 11.2 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.4 0.1 7.3 0.0 0.0 2.1 4.1 6.8 3.4 7.4 3.8 4.3 4.2 4.0 3.9 3.9 5.3 3.8 48.7 3.2 1.5 18.9 1.7 6.0 1.3 1.5 0.0 0.2 1.2 2.0 24.0 10.0 2.0 0.0 0.0 13.5 0.6 0.0 0.0 0.5 1.4 11.5 362.9 49.4 0.0 5.3 0.6 0.9 10.2 137.6 0.5 9.6 1.3 2.1 191.3 73.4 8.0 3.3 3.3 0.0 10.2 15.1 19.3 5.7 177.3 9.9 17.8 30.0 10.0 2.2 1.0 1.0 0.3 4.3 0.0 125.6 0.0 5.3 0.0 8.6 0.1 0.1 243.3 18.7 92.3 0.8 0.2 0.8 5.3 15.7 2.9 5.7 0.1 7.3 NID2 ENSG00000087303 "Nidogen 2" Q14112 14 52004803-52069228 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 60.8" "Cell type enhanced" "Detected in many" "Adipocytes: 31.0;Endothelial cells: 19.7;Fibroblasts: 46.0;Microglial cells: 19.7;Smooth muscle cells: 22.6;Theca cells: 19.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 285.4;ASC TERT1: 113.0;BJ: 152.1;BJ hTERT+: 131.8;HHSteC: 158.1;HSkMC: 591.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052460, HPA058772" Enhanced Enhanced "Plasma membrane" "Secreted to extracellular matrix" NA NA 6300000 "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA052460: AB_2681840, HPA058772: AB_2683815" "unprognostic (6.51e-2)" "unprognostic (3.55e-3)" "unprognostic (3.73e-2)" "unprognostic (3.25e-2)" "unprognostic (2.04e-1)" "unprognostic (1.94e-1)" "unprognostic (5.37e-2)" "unprognostic (3.05e-3)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (4.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.48e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (4.58e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (2.78e-4)" 28.3 5.2 0.9 9.2 1.2 0.7 9.6 0.6 1.4 7.5 44.0 8.8 2.3 17.4 5.8 5.4 6.7 19.0 15.6 1.4 0.5 4.8 5.9 6.1 3.5 1.8 0.6 18.9 3.4 13.2 2.5 60.8 0.5 8.4 6.8 0.1 3.6 10.4 4.3 1.7 3.5 11.4 1.1 1.9 6.8 1.4 0.9 2.1 31.6 5.5 1.4 15.4 5.4 1.6 0.0 3.4 76.6 0.0 285.4 113.0 0.2 152.1 131.8 14.5 15.0 0.4 0.0 0.0 22.2 17.3 0.0 10.7 9.9 0.1 3.9 0.1 2.0 0.0 3.0 0.0 158.1 0.0 0.0 591.5 0.0 59.6 0.1 82.5 8.1 0.1 0.0 0.0 8.6 0.0 0.0 0.4 3.3 0.0 5.1 23.5 0.2 0.1 19.9 0.0 0.0 1.8 0.0 0.1 0.0 10.0 0.0 0.0 0.9 54.4 0.6 33.0 0.0 0.0 0.0 0.1 17.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.2 0.6 1.4 1.4 0.5 1.8 0.6 0.5 1.1 0.9 1.6 31.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.6 1.4 0.2 0.3 2.1 0.0 0.0 1.8 0.0 0.7 0.7 3.7 0.0 0.1 14.0 1.5 11.3 19.7 0.0 0.0 0.8 0.0 1.1 46.0 1.1 0.4 1.3 0.4 8.6 0.0 1.6 0.0 1.7 2.0 0.0 0.3 1.2 4.4 6.2 0.3 3.6 19.7 1.0 0.0 0.0 2.0 4.8 0.2 1.3 8.6 0.1 0.2 1.7 0.4 0.0 0.8 6.6 6.1 22.6 0.2 0.1 0.1 1.0 0.8 0.4 19.1 3.0 0.2 NIPAL3 "DJ462O23.2, NPAL3" ENSG00000001461 "NIPA like domain containing 3" Q6P499 1 24415802-24472976 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 88.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.5;Oligodendrocytes: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039978 Approved Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA039978: AB_10697712" "unprognostic (9.36e-2)" "unprognostic (7.63e-2)" "unprognostic (2.88e-2)" "unprognostic (1.19e-2)" "unprognostic (5.96e-2)" "unprognostic (5.38e-2)" "unprognostic (3.72e-3)" "unprognostic (3.60e-2)" "unprognostic (2.43e-1)" "unprognostic (6.66e-2)" "unprognostic (2.79e-1)" "unprognostic (3.14e-1)" "prognostic favorable (3.03e-7)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (3.95e-4)" "unprognostic (2.85e-1)" 8.4 7.4 49.6 8.4 67.3 8.4 12.9 67.7 58.5 9.6 25.8 13.8 11.3 6.2 11.7 15.9 14.6 8.9 12.8 43.6 58.1 13.8 3.5 13.9 11.6 61.8 58.6 7.2 17.1 21.9 7.3 3.5 65.0 55.9 14.4 27.7 15.2 7.6 5.9 14.0 12.7 12.3 56.1 7.8 14.8 4.9 65.0 13.2 29.2 11.9 13.1 8.0 10.4 88.5 32.4 12.1 1.1 4.2 18.9 20.7 4.5 101.8 71.7 35.0 26.2 4.5 36.4 15.4 30.2 55.2 7.3 31.5 12.5 37.1 37.3 29.5 38.1 16.0 18.5 5.4 17.7 14.2 14.4 20.7 36.1 22.3 75.7 34.8 12.2 27.5 9.5 9.7 22.4 7.2 11.5 6.6 8.3 15.4 34.0 5.5 0.1 17.1 41.6 10.1 44.6 4.3 13.1 19.5 26.9 8.6 26.0 10.6 17.9 31.5 6.7 10.9 22.9 29.4 24.1 5.4 21.4 26.8 28.8 16.9 5.8 7.9 16.7 5.7 16.9 22.1 28.8 22.5 11.2 20.1 38.9 24.8 2.5 15.6 4.2 14.6 31.8 16.0 49.6 67.3 67.7 58.5 43.6 58.1 61.8 58.6 65.0 56.1 65.0 88.5 17.1 48.1 27.5 8.8 15.4 9.2 13.5 25.7 14.8 50.3 15.9 12.2 25.9 15.7 24.7 40.5 110.5 3.8 32.1 25.0 3.9 13.1 3.6 11.0 3.5 10.2 18.7 26.1 29.3 15.5 4.7 7.4 16.8 18.3 13.3 10.5 9.3 3.8 4.5 13.5 32.2 16.7 16.2 7.0 7.8 8.0 4.1 5.5 14.2 10.3 8.6 18.7 23.7 24.6 91.8 22.6 22.6 5.3 16.0 34.5 33.2 4.5 16.5 53.6 0.0 4.4 5.9 2.6 6.0 20.0 16.3 4.2 25.3 8.2 17.2 20.9 NIPBL "DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, IDN3, Scc2" ENSG00000164190 "NIPBL cohesin loading factor" Q6KC79 5 36876769-37066413 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Activator, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 303.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040834, HPA058239" Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA040834: AB_10796562, HPA058239: AB_2683650" "unprognostic (4.92e-2)" "unprognostic (9.77e-2)" "unprognostic (5.28e-2)" "unprognostic (8.10e-2)" "unprognostic (9.38e-2)" "unprognostic (6.02e-2)" "unprognostic (7.34e-2)" "unprognostic (3.04e-2)" "unprognostic (3.85e-2)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" "unprognostic (3.41e-1)" "unprognostic (1.04e-1)" "unprognostic (3.40e-2)" 11.5 9.4 5.6 14.7 8.6 25.1 13.5 12.0 7.3 12.9 7.8 12.2 10.0 13.4 6.6 11.4 10.5 11.1 7.7 5.3 5.9 11.6 12.7 11.9 16.5 7.3 6.6 17.6 13.1 19.6 5.0 13.9 8.2 11.1 12.2 22.4 11.2 10.7 9.5 14.2 13.2 12.4 6.3 15.3 13.4 14.2 6.9 29.8 17.2 14.3 16.7 12.6 7.5 11.1 22.5 13.1 33.3 15.6 20.7 22.3 24.4 17.6 19.3 18.9 15.7 18.2 22.6 33.5 11.3 21.6 22.2 19.2 28.9 15.9 27.0 27.9 14.7 40.9 57.4 13.3 14.0 48.4 26.4 16.5 19.3 21.3 28.1 18.1 24.0 20.8 39.3 24.5 17.9 10.8 33.8 18.1 16.0 12.9 11.3 28.2 51.9 13.0 13.1 31.4 24.5 17.2 84.6 22.5 18.0 26.2 23.0 27.3 26.3 24.9 27.1 21.0 13.3 17.7 25.5 39.1 13.6 32.4 19.1 10.9 2.9 4.3 3.2 2.2 3.0 2.8 2.7 2.9 2.3 3.1 2.9 3.3 7.7 2.8 3.3 3.4 2.1 1.6 5.6 8.6 12.0 7.3 5.3 5.9 7.3 6.6 8.2 6.3 6.9 11.1 80.6 131.4 108.6 169.8 84.8 48.4 66.2 34.2 58.1 62.6 43.6 49.4 87.0 38.6 63.3 33.1 77.2 44.1 107.1 45.9 5.9 55.5 13.4 72.9 75.7 74.1 41.5 85.4 179.2 46.7 34.1 64.3 61.2 91.7 84.0 77.7 44.6 28.2 37.1 40.4 165.5 46.3 38.7 51.8 46.6 15.1 66.5 86.7 24.9 236.1 103.3 49.2 97.9 229.2 303.7 55.0 48.6 56.4 84.5 66.4 45.2 12.2 65.2 72.8 52.6 102.9 80.1 185.8 133.6 58.2 47.0 75.9 92.0 73.8 42.9 88.0 NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Group enriched" "Detected in many" 4 "dendritic cells: 3163.4;NK-cells: 7721.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 5 "NB-4: 180.8;THP-1: 54.5;U-937: 46.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" 12.5 7.9 3.7 23.2 3.6 602.6 7.7 3.6 6.3 5.9 4.2 9.5 11.0 12.5 6.1 7.2 7.9 21.4 6.7 3.5 3.6 6.5 23.5 49.2 136.4 4.9 3.9 4.2 2.2 2.2 3.2 7.9 4.2 4.9 7.3 0.4 9.6 4.5 6.5 2.7 14.6 7.7 4.1 154.6 10.6 3.3 4.3 9.4 6.6 3.3 21.9 16.7 4.4 4.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.9 7.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.6 0.6 2.0 0.8 0.2 0.0 20.1 3.6 0.0 0.0 0.3 0.0 0.2 0.0 2.5 0.5 0.8 0.0 0.0 2.4 180.8 0.0 0.2 0.3 4.4 9.4 0.4 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.3 0.0 54.5 0.4 0.1 0.2 0.6 0.1 2.6 0.9 0.9 0.1 46.6 0.0 76.9 34.1 15.2 6827.0 131.7 2871.2 37.9 811.1 4295.0 87.1 15.4 261.0 3114.2 111.7 4796.8 104.8 67.1 17.5 4929.2 3.7 3.6 3.6 6.3 3.5 3.6 4.9 3.9 4.2 4.1 4.3 4.2 17.2 3.2 8.0 0.0 24.5 5.0 0.1 0.0 0.0 0.0 5.7 3.7 0.7 28.6 1.3 5.5 0.0 1.0 3163.4 1.9 3.9 1.0 0.2 2.7 3.6 7.1 0.0 186.5 0.0 0.0 0.8 5.2 17.3 4.2 24.1 0.2 55.3 9.9 15.0 0.0 0.0 0.5 0.0 132.9 10.2 0.3 0.0 55.5 17.8 1.0 49.4 0.0 7721.0 0.0 0.2 0.0 1.2 0.0 120.4 0.0 0.6 9.2 0.7 0.0 0.0 6.4 4.7 0.0 0.5 1.1 6.5 1.1 1321.5 0.0 1.1 0.1 NKX6-3 FLJ25169 ENSG00000165066 "NK6 homeobox 3" A6NJ46 8 41645177-41650817 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 10.8;stomach 1: 28.0" "Cell type enriched" "Detected in single" 5 "Gastric mucus-secreting cells: 2.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.1;stomach cancer: 3.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Daudi: 4.9;THP-1: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: Stomach - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.87e-1)" "unprognostic (9.91e-3)" "unprognostic (4.04e-1)" "unprognostic (5.73e-2)" "unprognostic (1.98e-1)" "unprognostic (1.65e-1)" "unprognostic (6.36e-2)" "unprognostic (1.13e-1)" "unprognostic (2.17e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-1)" 0.0 0.0 0.3 0.1 0.5 0.1 0.0 2.5 1.0 0.0 0.3 0.1 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 1.5 0.5 0.9 0.0 0.9 1.8 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.3 28.0 0.1 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 2.5 1.0 0.4 0.4 0.5 0.9 0.6 0.4 0.4 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NLGN1 KIAA1070 ENSG00000169760 "Neuroligin 1" Q8N2Q7 3 173396284-174286644 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biological rhythms, Cell adhesion" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.0;retina: 13.8" "Group enriched" "Detected in many" 31 "Excitatory neurons: 1484.7;Inhibitory neurons: 1700.0;Oligodendrocyte precursor cells: 4004.1;Oligodendrocytes: 1261.9" "Group enriched" "Detected in some" 9 "glioma: 3.8;melanoma: 2.2;renal cancer: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 25.9;HUVEC TERT2: 24.9;RH-30: 26.2;WM-115: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006572, HPA006680, CAB033261" Enhanced Uncertain "Nuclear bodies,Plasma membrane" "Intracellular and membrane" NA NA 82000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nuclear bodies" "CAB033261: AB_2151659, HPA006572: , HPA006680: AB_1854400" "unprognostic (2.81e-1)" "unprognostic (9.86e-2)" "unprognostic (3.08e-5)" "unprognostic (7.52e-5)" "unprognostic (1.03e-1)" "unprognostic (2.31e-1)" "unprognostic (6.67e-2)" "unprognostic (6.65e-2)" "unprognostic (1.78e-1)" "unprognostic (8.07e-2)" "unprognostic (3.21e-3)" "unprognostic (1.86e-2)" "unprognostic (1.97e-1)" "unprognostic (4.08e-2)" "unprognostic (8.81e-2)" "unprognostic (2.41e-3)" "unprognostic (5.37e-2)" 2.0 1.0 12.6 0.5 10.8 0.0 0.7 31.0 12.1 3.1 0.0 2.0 0.2 2.1 2.5 2.5 3.0 1.6 3.2 12.5 15.2 2.9 0.0 0.4 0.2 5.3 5.4 1.3 0.8 0.7 1.8 0.5 4.0 2.2 0.9 13.8 0.3 3.0 0.2 0.3 0.6 2.7 4.4 0.0 0.8 7.0 20.5 0.2 0.9 1.0 0.1 2.9 1.3 7.2 0.1 0.0 6.1 0.0 11.8 12.4 0.0 5.2 12.8 0.6 0.8 0.0 0.5 0.0 0.2 25.9 4.7 0.0 3.7 0.0 1.3 0.0 6.0 1.7 0.1 0.0 0.0 0.0 0.0 9.7 0.1 0.0 0.0 10.0 24.9 0.0 0.0 1.7 0.1 0.0 0.0 0.0 7.2 0.0 1.7 0.0 26.2 6.4 4.7 0.1 2.5 1.7 0.0 0.0 12.3 1.1 0.6 0.0 3.1 13.5 1.3 9.9 11.6 11.7 0.0 0.0 4.6 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 10.8 31.0 12.1 12.5 15.2 5.3 5.4 4.0 4.4 20.5 7.2 0.3 0.0 0.5 66.6 0.0 0.8 0.4 0.0 0.6 14.3 0.1 0.0 4.4 0.0 0.0 3.7 4.2 0.3 0.0 0.0 0.0 0.3 55.9 0.6 12.4 0.8 0.0 0.0 1484.7 0.0 0.2 8.2 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 1700.0 0.0 0.0 0.0 0.3 12.5 25.7 0.4 14.2 60.9 0.0 24.9 0.0 4004.1 1261.9 0.1 0.0 14.3 0.0 2.6 0.0 8.5 0.0 10.3 6.6 2.9 2.1 0.4 1.6 0.1 0.9 0.1 0.1 1.6 0.0 0.3 NLGN3 "ASPGX1, AUTSX1, HNL3, KIAA1480" ENSG00000196338 "Neuroligin 3" Q9NZ94 X 71144831-71171201 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Asperger syndrome, Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;seminal vesicle: 12.5" "Cell type enhanced" "Detected in some" "Astrocytes: 19.6;Inhibitory neurons: 12.7;Oligodendrocyte precursor cells: 92.0;Oligodendrocytes: 43.7;Peritubular cells: 17.3" "Cancer enriched" "Detected in many" 19 "glioma: 37.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.7;NTERA-2: 5.3;SH-SY5Y: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003183, HPA004066" Enhanced Supported "Golgi apparatus,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus, Cell Junctions" "HPA003183: AB_1079469, HPA004066: AB_2732397" "unprognostic (4.06e-2)" "unprognostic (1.77e-1)" "unprognostic (1.59e-2)" "unprognostic (2.38e-2)" "unprognostic (2.42e-1)" "unprognostic (3.87e-1)" "unprognostic (6.52e-2)" "unprognostic (1.63e-1)" "unprognostic (7.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (6.18e-2)" "unprognostic (4.27e-9)" "unprognostic (4.28e-2)" "unprognostic (1.90e-1)" "unprognostic (2.22e-5)" "unprognostic (9.01e-2)" 0.5 6.6 10.1 0.8 8.5 1.4 0.4 6.4 11.1 1.9 0.0 1.8 0.2 2.7 6.4 0.6 4.3 1.4 1.1 10.3 10.2 0.3 0.1 0.6 0.4 7.3 7.0 4.4 0.3 0.5 1.0 0.6 4.8 6.0 0.5 1.9 0.6 12.5 0.1 0.7 0.7 1.9 5.5 0.6 0.6 2.6 7.3 0.4 0.4 0.4 0.2 0.7 1.2 9.7 0.0 0.5 6.7 0.2 1.6 0.6 1.2 0.0 0.0 0.0 0.1 0.1 0.3 0.5 0.5 0.1 0.0 0.1 0.2 0.0 0.1 0.4 0.9 0.4 0.4 0.0 0.0 0.1 0.4 0.4 0.1 0.2 0.0 0.3 0.1 2.0 0.5 1.5 0.0 0.3 0.5 1.2 5.3 0.0 0.0 0.6 0.2 0.3 0.0 0.8 1.7 2.5 0.2 0.0 0.6 0.8 0.0 0.3 0.1 0.1 0.8 0.2 0.0 1.1 1.1 0.5 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 10.1 8.5 6.4 11.1 10.3 10.2 7.3 7.0 4.8 5.5 7.3 9.7 0.3 0.0 0.0 19.6 0.0 0.6 0.3 0.2 1.2 2.6 0.3 0.9 0.4 0.0 0.1 0.0 0.0 1.0 0.2 0.2 0.0 0.1 1.3 0.2 1.1 0.5 0.0 0.0 11.3 0.0 0.2 1.3 0.0 0.4 0.0 1.0 0.7 0.0 0.1 0.0 12.7 0.0 0.0 0.0 0.8 3.9 2.1 0.2 0.0 2.8 0.1 2.5 0.0 92.0 43.7 0.2 0.1 17.3 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.2 0.6 0.2 0.0 0.1 0.4 0.3 0.2 4.5 0.1 0.3 NLGN4X "HLNX, KIAA1260, NLGN, NLGN4" ENSG00000146938 "Neuroligin 4 X-linked" Q8N0W4 X 5840637-6228867 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Asperger syndrome, Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.5;lymphoid tissue: 14.3" "Cell type enhanced" "Detected in many" "Astrocytes: 113.9;Excitatory neurons: 162.2;Inhibitory neurons: 236.8;Oligodendrocyte precursor cells: 702.7" "Group enriched" "Detected in many" 4 "endometrial cancer: 2.7;glioma: 8.5;testis cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 55.6;NTERA-2: 44.1;SuSa: 42.7" HPA001651 Approved NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA001651: AB_1079470" "unprognostic (2.21e-1)" "unprognostic (4.01e-2)" "unprognostic (1.11e-1)" "unprognostic (8.57e-2)" "unprognostic (1.28e-1)" "unprognostic (1.52e-1)" "unprognostic (1.36e-1)" "unprognostic (1.04e-1)" "unprognostic (1.67e-1)" "unprognostic (9.49e-2)" "unprognostic (1.48e-2)" "unprognostic (9.32e-2)" "unprognostic (5.10e-3)" "unprognostic (7.16e-4)" "unprognostic (6.70e-2)" "unprognostic (2.98e-2)" "unprognostic (1.10e-2)" 3.4 1.3 8.8 1.8 10.1 0.0 2.2 9.8 12.7 5.1 0.0 3.4 1.3 2.3 0.4 0.7 2.0 2.5 4.5 14.8 28.5 0.3 1.3 1.1 0.8 6.5 5.6 11.6 0.4 5.2 1.7 3.6 4.4 1.1 1.9 9.2 0.8 1.9 0.3 0.6 2.6 3.7 1.6 2.2 1.1 2.6 8.9 14.3 0.7 0.2 0.5 2.1 1.4 4.2 0.0 0.0 55.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 7.4 0.0 44.1 0.0 0.1 0.0 0.0 0.1 4.1 11.5 2.7 3.5 0.0 0.1 0.0 42.7 5.7 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 10.1 9.8 12.7 14.8 28.5 6.5 5.6 4.4 1.6 8.9 4.2 12.1 0.0 0.5 113.9 0.3 0.3 0.1 0.2 0.0 15.0 5.2 3.4 2.8 0.0 0.1 0.0 25.0 3.7 0.1 0.0 0.0 0.0 0.1 19.7 69.5 2.5 0.0 0.0 162.2 0.0 2.4 9.6 0.0 33.2 0.0 2.2 1.8 0.0 0.6 0.0 236.8 0.0 0.0 0.3 0.5 0.7 18.0 0.3 14.2 4.7 0.0 12.5 0.0 702.7 68.3 0.0 0.0 29.7 0.1 0.0 0.0 0.1 0.7 3.3 13.1 18.4 5.0 2.0 5.5 0.2 0.6 3.6 0.5 8.8 0.0 0.3 NLGN4Y KIAA0951 ENSG00000165246 "Neuroligin 4 Y-linked" Q8NFZ3 Y 14522573-14845650 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 6.3;seminal vesicle: 7.5" "Cell type enhanced" "Detected in many" "Astrocytes: 48.0;Basal squamous epithelial cells: 45.5;Excitatory neurons: 146.1;Inhibitory neurons: 108.0;Oligodendrocyte precursor cells: 220.7;Oligodendrocytes: 46.7" "Cancer enhanced" "Detected in many" "glioma: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.1;fHDF/TERT166: 25.3;HDLM-2: 30.2;hTCEpi: 21.1;SuSa: 19.9;U-138 MG: 23.1" HPA001651 Approved "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA001651: AB_1079470" "unprognostic (2.31e-1)" "unprognostic (9.19e-2)" "unprognostic (2.84e-5)" "unprognostic (7.85e-2)" "unprognostic (6.46e-2)" "unprognostic (8.80e-3)" "unprognostic (7.71e-2)" "unprognostic (6.26e-2)" "unprognostic (5.89e-2)" "unprognostic (7.20e-3)" "unprognostic (1.88e-1)" "unprognostic (5.65e-2)" 1.2 1.3 1.3 0.5 1.5 0.0 1.1 1.7 4.1 0.0 0.3 2.0 0.4 0.0 1.8 2.0 0.0 2.4 0.5 2.1 1.6 1.3 2.1 0.6 0.4 0.8 0.6 0.0 1.6 1.7 2.1 0.3 0.8 6.3 1.4 1.3 1.8 7.5 0.3 1.1 0.9 0.0 0.9 0.4 0.9 0.5 0.5 0.1 1.1 2.2 1.1 3.4 0.0 2.5 0.0 1.3 0.0 0.0 0.0 0.0 0.0 7.1 32.1 2.0 2.6 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 5.0 30.2 0.0 0.0 0.0 4.9 3.3 0.1 0.0 10.7 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 2.2 0.0 6.4 0.1 0.0 0.0 2.0 0.0 7.5 12.4 4.2 0.0 0.0 0.0 0.1 19.9 0.0 0.7 9.3 23.1 0.0 0.0 5.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 1.5 1.7 4.1 2.1 1.6 0.8 0.6 0.8 0.9 0.5 2.5 0.0 0.0 1.3 48.0 1.1 3.4 10.8 12.0 45.5 9.0 0.0 0.0 1.0 5.7 6.4 7.3 0.0 0.3 0.0 0.0 0.0 2.6 0.1 0.0 0.0 3.0 0.0 0.0 146.1 0.0 0.2 8.6 2.0 0.0 0.0 0.0 0.0 0.6 0.2 6.7 108.0 0.0 4.1 0.0 5.1 0.2 2.8 0.1 1.8 29.0 2.6 4.3 0.0 220.7 46.7 0.0 0.0 8.2 0.4 14.1 0.0 0.8 3.3 0.7 0.0 4.7 1.1 0.4 0.8 12.3 3.1 0.3 0.9 0.0 0.2 11.8 NLRP5 "CLR19.8, MATER, NALP5, PAN11, PYPAF8" ENSG00000171487 "NLR family pyrin domain containing 5" P59047 19 55999726-56061810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 50 "parathyroid gland: 22.4" "Cell type enhanced" "Detected in some" "Microglial cells: 1.0;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "Karpas-707: 1.3;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047260, HPA056271" Uncertain Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 9: U-2 OS - Unknown function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "HPA047260: , HPA056271: AB_2683083" "unprognostic (9.67e-2)" "unprognostic (2.22e-2)" "unprognostic (5.03e-1)" "unprognostic (7.78e-2)" "unprognostic (1.72e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 22.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NMB "MGC17211, MGC2277, MGC3936" ENSG00000197696 "Neuromedin B" P08949 15 84655129-84658563 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 68.3;brain: 58.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 319.5;Club cells: 164.2;Ductal cells: 123.9" "Cancer enhanced" "Detected in all" "glioma: 93.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 90.1" "Region enriched" "Detected in all" 16 "olfactory bulb: 168.0" "Group enriched" "Detected in all" 5 "olfactory bulb: 43.3;pons: 14.1" CAB019302 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted to blood" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "Plasma membrane" "CAB019302: " "unprognostic (2.44e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-3)" "unprognostic (3.79e-1)" "prognostic favorable (3.43e-4)" "unprognostic (3.81e-1)" "unprognostic (6.45e-2)" "unprognostic (1.45e-2)" "unprognostic (2.17e-1)" "unprognostic (4.36e-1)" "unprognostic (7.24e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.25e-4)" "unprognostic (7.92e-3)" "unprognostic (1.45e-1)" "unprognostic (1.71e-2)" "unprognostic (1.00e-1)" 68.3 24.0 19.9 4.1 17.9 6.0 30.7 18.2 23.5 8.3 16.3 5.3 3.1 7.5 4.9 6.9 8.6 4.8 5.4 21.4 58.9 10.7 3.1 6.2 5.7 29.3 22.7 7.1 8.4 4.5 9.8 1.9 26.2 5.0 2.9 3.0 7.4 2.5 2.5 4.9 4.1 4.7 22.4 4.8 5.5 11.9 21.4 4.5 17.7 3.1 3.0 8.5 6.5 44.7 90.1 35.3 6.1 1.3 17.1 7.7 0.8 4.7 10.5 12.5 16.6 12.9 23.5 3.4 12.9 14.7 0.1 15.0 34.0 7.0 7.4 30.3 36.7 12.4 13.2 59.7 4.4 8.2 13.6 7.6 2.8 18.2 7.2 7.6 17.9 23.3 0.2 1.4 6.9 55.2 8.8 30.0 22.9 18.0 8.9 25.7 0.1 38.7 11.5 7.3 3.1 34.6 8.2 5.1 40.5 6.0 5.9 33.8 4.0 2.4 10.3 10.3 7.9 0.7 9.9 8.2 26.3 52.9 14.1 0.0 1.0 7.8 7.9 0.7 2.9 5.9 5.9 7.7 4.5 11.3 5.8 4.1 1.6 1.8 0.5 13.4 7.6 3.4 19.9 17.9 18.2 23.5 21.4 58.9 29.3 22.7 26.2 22.4 21.4 44.7 39.0 3.2 2.7 5.5 13.6 15.6 29.5 319.5 21.6 1.9 30.7 37.6 3.5 20.0 164.2 31.3 0.0 2.4 25.3 5.3 13.7 123.9 33.7 21.3 7.3 19.6 18.6 7.4 0.6 58.2 14.1 19.7 11.2 15.6 5.7 12.0 7.5 3.7 32.3 5.0 1.2 6.5 18.3 8.8 86.4 29.0 4.4 26.0 33.8 1.9 18.5 6.5 25.7 2.0 1.0 45.2 5.1 3.8 32.5 39.3 0.8 32.0 57.8 4.1 13.1 22.5 28.6 24.0 21.6 29.5 12.8 3.1 19.7 8.2 9.1 60.6 NME1 "NDPKA, NM23, NM23-H1" ENSG00000239672 "NME/NM23 nucleoside diphosphate kinase 1" P15531 17 51153559-51162428 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Endocytosis, Neurogenesis, Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008467, CAB040571, HPA041113" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 21000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "CAB040571: , HPA008467: AB_1079492, HPA041113: AB_2677305" "unprognostic (2.24e-1)" "unprognostic (2.01e-1)" "unprognostic (3.48e-3)" "unprognostic (5.96e-2)" "unprognostic (9.71e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (2.60e-5)" "unprognostic (4.54e-2)" "unprognostic (3.35e-1)" "unprognostic (2.33e-3)" "unprognostic (2.90e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.07e-9)" "unprognostic (9.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.83e-1)" "unprognostic (9.46e-2)" 63.6 84.4 79.3 74.7 81.6 77.0 63.1 78.7 102.2 38.2 79.0 60.1 38.8 49.7 46.8 91.0 48.6 20.8 37.7 88.0 92.0 65.4 83.2 41.3 73.9 83.9 78.4 33.6 67.8 52.8 47.4 39.2 82.4 38.7 77.6 218.4 50.7 30.4 35.6 57.5 33.1 66.3 76.5 48.5 41.8 25.3 81.0 61.1 41.3 20.9 95.8 72.2 48.9 80.1 483.6 833.1 285.9 444.8 118.6 183.7 479.7 355.3 227.3 652.2 489.7 656.9 288.1 754.2 372.4 304.1 272.4 252.1 542.5 553.3 553.4 398.4 729.3 504.9 605.8 975.9 237.1 575.8 243.8 177.8 341.7 493.1 458.6 120.6 404.6 247.8 739.0 270.0 392.8 720.4 715.2 647.1 390.7 957.5 739.3 446.9 587.6 751.3 511.5 320.2 418.6 461.1 188.1 521.0 385.3 246.2 554.0 419.6 279.5 476.9 452.2 307.0 774.4 374.0 840.9 956.3 286.2 480.4 385.8 1.1 55.0 2.1 47.2 77.1 69.3 96.4 50.3 53.8 134.0 67.6 54.3 60.4 1.7 69.6 48.6 84.8 49.1 68.4 79.3 81.6 78.7 102.2 88.0 92.0 83.9 78.4 82.4 76.5 81.0 80.1 53.1 32.1 30.5 0.0 71.3 132.4 97.5 198.8 88.8 283.3 98.8 118.1 34.2 65.8 92.3 71.7 285.7 180.0 25.4 54.2 150.6 211.3 34.2 40.2 107.2 85.1 89.7 81.8 0.0 201.5 269.7 85.0 64.2 37.2 45.7 113.5 27.8 123.3 207.1 40.4 0.0 107.4 101.7 25.7 88.9 93.7 61.2 48.9 129.9 0.0 47.2 105.6 27.8 0.0 0.0 194.0 50.5 58.6 113.8 170.6 12.2 195.2 42.0 323.7 13.1 83.0 182.9 22.7 98.8 139.4 133.1 88.5 38.0 215.5 157.7 98.2 NME1-NME2 "NM23-LV, NMELV" ENSG00000011052 "NME1-NME2 readthrough" 17 51153590-51171744 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 51.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 43.5;Basal keratinocytes: 38.4;Basal respiratory cells: 23.3;Club cells: 31.1;granulocytes: 22.7;Langerhans cells: 35.0;Melanocytes: 23.2;Suprabasal keratinocytes: 51.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002169, HPA008467, HPA041113, CAB076057" Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 77: Retina - Visual perception" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB002169: AB_563917, CAB076057: , HPA008467: AB_1079492, HPA041113: AB_2677305" "unprognostic (2.39e-1)" "unprognostic (5.29e-2)" "unprognostic (9.70e-2)" "unprognostic (5.13e-2)" "prognostic favorable (6.66e-4)" "unprognostic (2.46e-2)" "unprognostic (4.82e-3)" "unprognostic (8.39e-2)" "unprognostic (2.30e-2)" "unprognostic (1.53e-1)" "unprognostic (4.58e-6)" "unprognostic (1.03e-1)" "unprognostic (2.74e-6)" "unprognostic (1.84e-1)" "unprognostic (9.72e-2)" "unprognostic (1.50e-1)" "unprognostic (1.43e-3)" 12.3 21.0 7.2 15.1 7.4 10.9 8.7 6.5 10.3 8.7 6.3 6.7 3.6 9.3 0.8 14.7 9.4 2.2 9.9 8.7 6.8 12.4 16.4 9.2 8.7 7.8 6.7 5.6 16.6 6.4 11.9 7.1 7.8 6.8 2.9 51.2 13.8 2.2 12.9 12.2 4.9 6.8 6.5 7.9 9.0 3.0 7.7 6.2 7.4 3.6 3.7 13.1 9.9 7.3 22.4 5.5 21.2 48.3 27.9 13.1 7.7 32.3 20.8 15.9 9.5 11.1 8.6 30.1 34.3 41.3 33.2 21.9 25.1 44.7 8.8 51.0 46.6 15.2 9.1 22.7 30.5 25.5 42.2 25.4 36.2 21.2 31.4 49.6 28.0 38.8 21.2 36.7 12.3 14.6 141.2 37.4 19.6 66.5 9.5 49.5 21.0 85.0 23.0 9.4 70.1 56.4 13.9 112.7 38.3 37.8 87.8 86.3 34.1 57.0 14.6 76.8 26.2 60.8 52.2 41.4 26.7 24.6 46.4 0.4 16.0 0.7 18.2 24.1 26.9 14.1 15.7 17.1 45.9 23.4 13.9 16.9 1.7 14.4 11.9 28.4 16.9 20.8 7.2 7.4 6.5 10.3 8.7 6.8 7.8 6.7 7.8 6.5 7.7 7.3 0.0 16.0 43.5 0.0 1.5 38.4 0.0 23.3 2.2 0.0 0.0 0.0 2.2 0.0 31.1 0.0 0.0 0.0 0.1 8.0 0.0 0.0 0.0 0.2 0.2 5.1 1.8 0.4 3.9 0.0 0.1 12.1 1.5 0.2 22.7 0.1 0.4 0.6 0.0 0.0 3.5 7.2 10.2 0.0 35.0 0.0 0.3 6.8 23.2 0.0 0.0 0.0 0.0 2.0 0.9 0.0 1.1 0.0 2.0 0.0 0.0 0.1 16.3 0.0 0.0 0.0 16.4 0.1 0.0 3.8 51.9 0.0 3.0 0.0 7.8 0.1 NME3 "DR-nm23, NDPKC, NM23-H3" ENSG00000103024 "NME/NM23 nucleoside diphosphate kinase 3" Q13232 16 1770286-1771730 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 70.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041113, HPA052733" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 12000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA041113: AB_2677305, HPA052733: AB_2681930" "prognostic favorable (6.81e-5)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (1.15e-3)" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (4.54e-2)" "unprognostic (1.13e-1)" "unprognostic (6.22e-3)" "unprognostic (4.40e-2)" "unprognostic (4.43e-2)" "unprognostic (7.09e-3)" "unprognostic (1.79e-1)" "unprognostic (3.84e-1)" "unprognostic (3.64e-1)" "unprognostic (6.11e-3)" 34.0 84.4 21.3 8.0 22.7 3.9 34.2 21.0 36.3 41.9 16.8 47.7 15.9 36.7 3.4 27.2 44.3 2.1 36.0 20.2 23.1 44.6 36.3 29.1 5.4 23.7 22.2 43.7 37.2 4.5 71.9 5.2 19.6 59.4 3.1 1.8 35.9 13.0 17.1 31.1 33.8 3.2 22.5 39.4 38.6 16.0 22.0 1.0 40.3 3.1 1.9 38.5 33.5 24.9 1.6 26.9 0.6 21.8 6.1 3.2 2.5 15.7 4.5 2.7 2.1 0.0 31.8 0.4 42.6 2.2 2.8 23.0 1.3 8.8 0.3 32.1 70.9 0.0 12.0 13.0 11.3 5.5 9.8 14.0 7.9 2.7 1.5 5.1 5.6 0.2 11.2 4.4 2.7 40.4 0.4 10.8 28.0 5.4 21.5 15.3 0.3 43.5 4.5 1.2 30.6 23.6 47.1 35.2 4.2 1.2 33.7 13.1 19.9 5.8 21.4 18.5 10.8 11.1 3.7 2.5 8.1 0.9 13.3 10.0 50.7 34.6 33.3 49.6 32.9 36.8 46.3 31.4 45.1 31.9 39.6 31.3 10.8 44.8 55.4 70.3 45.4 41.3 21.3 22.7 21.0 36.3 20.2 23.1 23.7 22.2 19.6 22.5 22.0 24.9 128.8 35.3 62.7 69.9 64.6 72.5 141.3 97.7 179.8 116.3 147.3 165.6 28.0 90.1 76.6 126.9 60.5 86.6 77.9 76.2 60.7 62.9 22.1 66.5 102.9 84.1 135.5 25.7 34.6 37.6 46.3 100.9 76.0 77.6 50.8 71.6 99.9 63.0 74.8 65.6 30.2 109.4 50.8 60.3 91.0 20.3 149.5 71.1 81.8 29.0 136.5 126.9 77.2 40.7 63.7 37.0 104.7 127.5 93.1 98.4 157.2 150.2 70.9 126.7 118.3 75.9 100.8 2.0 40.4 100.9 65.6 46.1 87.3 183.8 107.6 100.6 NMS ENSG00000204640 "Neuromedin S" Q5H8A3 2 100470482-100483280 "Predicted secreted proteins" Neuropeptide "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "medulla oblongata: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HL-60: 8.4;HMC-1: 4.8" "Group enriched" "Detected in some" 4 "basal ganglia: 2.4;hypothalamus: 5.4;pons and medulla: 1.3" "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.9 2.7 0.1 0.2 1.7 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NMU ENSG00000109255 "Neuromedin U" P48645 4 55595229-55636698 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.2;skin 1: 38.5;vagina: 30.7" "Group enriched" "Detected in many" 4 "Squamous epithelial cells: 212.4;Suprabasal keratinocytes: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "MAIT T-cell: 3.6;memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 37 "T-cells: 3.6" "Cell line enhanced" "Detected in many" "Daudi: 90.2;HaCaT: 382.6;K-562: 311.3;Karpas-707: 135.7" "Group enriched" "Detected in some" 8 "hypothalamus: 1.1;pons and medulla: 4.5" "Low region specificity" "Detected in some" HPA025926 Uncertain "Secreted in other tissues" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA025926: AB_1854539" "unprognostic (4.42e-2)" "unprognostic (1.00e-1)" "unprognostic (5.83e-2)" "prognostic unfavorable (2.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.19e-2)" "unprognostic (7.12e-2)" "unprognostic (7.29e-3)" "unprognostic (9.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.07e-10)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (2.54e-2)" "unprognostic (5.55e-2)" 0.1 0.3 0.4 0.7 0.5 9.7 1.5 0.6 1.1 12.3 0.0 1.4 0.8 0.1 0.0 100.2 0.2 0.0 0.2 0.3 2.8 0.2 0.0 0.8 0.5 1.1 2.6 0.1 0.1 0.0 2.3 0.8 0.8 0.2 0.8 0.1 14.3 0.2 0.1 38.5 1.4 0.2 3.0 0.1 4.0 2.2 6.8 1.7 2.5 0.0 7.7 0.1 30.7 0.4 41.3 0.3 22.1 5.6 0.0 0.0 0.0 0.0 0.0 2.9 7.8 0.3 61.5 90.2 8.6 0.0 8.5 382.6 46.1 3.3 2.3 5.6 25.1 0.6 36.0 0.0 0.0 0.0 0.3 0.0 4.2 0.0 3.0 10.0 0.4 6.4 311.3 135.7 0.3 9.9 1.2 0.2 11.7 7.5 11.4 0.2 0.0 0.5 1.9 0.4 19.5 49.0 30.9 0.8 0.1 4.2 20.9 0.1 2.7 0.2 27.5 0.3 54.5 39.1 0.3 0.0 18.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.6 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.6 1.1 0.3 2.8 1.1 2.6 0.8 3.0 6.8 0.4 0.0 0.0 2.3 0.0 0.6 16.3 0.6 16.2 4.0 0.2 0.9 1.3 0.1 0.0 8.0 0.0 0.0 2.0 0.0 0.6 0.0 0.1 0.4 3.9 0.3 0.7 0.0 14.5 0.2 0.2 0.1 4.4 29.6 5.8 1.3 0.9 0.0 0.1 0.3 0.0 17.2 0.8 20.3 0.0 1.6 0.3 0.0 0.2 3.6 0.0 0.1 2.0 0.0 1.0 0.2 2.4 0.2 0.0 1.2 0.4 0.0 0.0 7.0 0.0 0.0 0.0 1.2 5.8 10.0 212.4 73.6 0.1 0.7 0.2 2.6 12.0 NOBOX "OG2, Og2x" ENSG00000106410 "NOBOX oogenesis homeobox" O60393 7 144397240-144410227 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Oogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Premature ovarian failure" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (7.88e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NODAL ENSG00000156574 "Nodal growth differentiation factor" Q96S42 10 70431936-70447951 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3;skeletal muscle: 2.3" "Group enriched" "Detected in some" 26 "Early spermatids: 15.4;Late spermatids: 38.5" "Cancer enriched" "Detected in some" 10 "testis cancer: 20.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.9;SH-SY5Y: 1.4;SuSa: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA045201 Uncertain "Secreted to blood" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "HPA045201: AB_2679252" "unprognostic (3.07e-2)" "unprognostic (2.10e-1)" "unprognostic (1.51e-2)" "unprognostic (2.41e-1)" "unprognostic (1.70e-1)" "unprognostic (4.57e-2)" "unprognostic (1.50e-1)" "unprognostic (1.65e-1)" "unprognostic (5.66e-3)" "unprognostic (3.12e-2)" "unprognostic (8.77e-2)" "unprognostic (1.61e-1)" "unprognostic (1.63e-5)" "unprognostic (4.37e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (2.02e-1)" 0.7 0.0 0.7 0.0 0.6 0.6 0.5 2.3 0.6 0.6 0.0 0.4 0.2 0.3 0.0 0.3 0.3 0.2 0.3 0.5 0.6 0.1 0.1 0.4 0.2 0.7 0.6 0.3 0.1 0.0 0.1 0.2 0.7 0.2 0.0 1.3 0.2 0.0 2.3 1.0 0.2 0.0 0.5 0.2 0.2 1.9 0.6 0.2 0.1 0.0 0.0 0.4 0.4 0.6 0.3 0.2 0.8 0.9 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.9 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.2 0.1 0.2 0.5 0.2 0.0 0.2 0.2 0.5 0.0 0.1 0.1 1.4 0.4 0.1 0.0 3.5 0.4 0.1 0.0 0.0 0.2 0.1 0.1 0.5 1.1 1.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.6 2.3 0.6 0.5 0.6 0.7 0.6 0.7 0.5 0.6 0.6 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 38.5 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 NOMO3 ENSG00000103226 "NODAL modulator 3" P69849 16 16232506-16300806 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 30.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 9.3" "HPA046697, HPA061174" Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA046697: AB_2679758, HPA061174: AB_2684444" "unprognostic (1.21e-1)" "unprognostic (1.41e-2)" "unprognostic (6.46e-2)" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.33e-1)" "unprognostic (9.81e-2)" "unprognostic (1.94e-1)" "unprognostic (1.25e-1)" "unprognostic (8.02e-2)" "unprognostic (6.25e-2)" "unprognostic (8.43e-2)" "unprognostic (7.86e-3)" "unprognostic (1.82e-1)" "unprognostic (1.65e-1)" "unprognostic (1.10e-2)" "unprognostic (1.22e-1)" 5.7 5.8 3.1 0.7 3.2 2.7 5.2 4.4 4.6 5.2 1.6 6.5 0.7 7.7 0.8 4.8 5.5 0.3 20.3 3.4 3.0 4.3 4.4 6.7 0.4 3.0 2.8 5.4 30.0 0.5 4.3 0.8 3.3 3.8 1.0 3.1 5.5 0.4 22.1 5.1 5.1 0.4 2.4 4.0 8.7 3.5 3.5 0.5 4.9 0.1 0.7 6.6 4.5 4.3 1.3 2.9 0.8 2.8 0.6 2.6 1.2 1.9 1.8 2.4 1.3 1.1 1.5 1.3 9.3 1.0 0.4 1.0 2.7 1.7 1.9 1.3 1.9 1.3 3.5 6.6 0.9 1.6 7.0 1.0 6.1 3.4 0.8 1.5 0.8 2.0 1.1 2.1 1.0 5.9 0.5 3.0 0.8 0.4 1.9 2.2 2.6 4.7 0.7 1.1 1.1 1.8 1.3 2.0 1.3 1.5 1.8 1.3 1.5 1.1 1.8 1.9 1.1 2.4 1.9 1.7 2.4 3.0 1.7 0.0 0.2 0.3 0.2 0.3 0.1 0.4 0.3 0.4 0.4 0.1 0.1 0.3 0.2 0.3 0.1 0.2 0.3 0.3 3.1 3.2 4.4 4.6 3.4 3.0 3.0 2.8 3.3 2.4 3.5 4.3 1.3 3.2 4.1 2.9 3.3 10.5 3.7 3.0 2.2 5.7 2.8 1.8 8.2 8.6 4.3 3.7 12.5 2.0 5.2 2.0 0.0 1.2 1.8 2.2 2.2 3.6 3.5 4.0 4.4 1.5 1.4 3.1 5.1 2.2 4.5 8.7 5.3 2.9 1.6 6.7 5.4 1.5 2.0 4.9 4.4 2.2 2.1 2.7 1.8 2.8 3.3 1.1 7.2 5.0 7.2 1.8 1.6 1.2 3.2 2.9 2.1 1.0 6.1 5.2 6.6 4.3 2.3 8.2 6.6 1.5 11.2 2.5 3.5 5.2 1.9 3.2 NOS3 "ECNOS, eNOS" ENSG00000164867 "Nitric oxide synthase 3" P29474 7 150991017-151014588 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 62.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.4;Early spermatids: 81.9;Endothelial cells: 32.6;Hepatic stellate cells: 29.3;Late spermatids: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "BEWO: 23.1;HUVEC TERT2: 44.7;K-562: 16.6;TIME: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002168 Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002168: AB_564072" "unprognostic (6.53e-2)" "unprognostic (3.36e-1)" "unprognostic (1.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (6.97e-2)" "unprognostic (2.56e-1)" "unprognostic (9.40e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" 19.3 6.3 8.4 5.8 6.8 0.8 13.2 5.7 6.7 7.3 3.4 5.9 2.6 9.7 0.4 5.8 8.1 4.7 20.6 5.7 6.1 24.2 4.3 11.2 2.7 9.2 7.7 3.2 2.9 1.2 7.2 4.8 8.6 7.6 1.2 0.8 4.4 1.7 3.9 4.2 6.7 3.7 7.5 62.4 5.4 7.2 11.0 0.6 9.1 3.5 1.2 9.7 7.4 6.0 0.4 0.1 1.3 4.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.3 2.2 0.4 2.1 0.0 0.2 0.7 0.0 0.1 0.0 0.0 0.4 2.2 0.3 6.4 0.6 0.5 10.4 0.1 0.2 0.0 0.0 0.1 44.7 5.1 16.6 3.6 0.0 0.0 0.2 0.5 1.7 0.7 0.1 3.0 0.0 1.8 0.0 0.3 0.5 0.4 0.2 1.4 0.0 0.4 0.1 1.4 82.5 0.2 0.7 0.4 0.1 2.4 8.9 2.2 0.0 7.5 0.0 0.2 0.1 0.1 1.1 0.2 0.7 0.3 1.7 0.9 0.2 0.5 2.3 0.9 0.3 0.2 0.2 0.2 2.1 0.5 8.4 6.8 5.7 6.7 5.7 6.1 9.2 7.7 8.6 7.5 11.0 6.0 20.4 9.6 2.2 0.3 0.7 0.9 0.1 0.1 0.0 0.2 0.2 0.3 3.1 0.0 0.7 0.0 0.0 0.2 0.7 0.1 0.0 1.0 81.9 4.9 0.7 32.6 0.0 0.0 0.2 0.0 0.1 2.9 0.5 3.2 5.7 0.7 29.3 0.7 0.4 0.0 0.2 0.4 0.0 0.6 0.5 29.3 0.9 0.4 0.0 7.5 0.0 0.3 0.0 0.0 0.0 0.8 0.0 1.2 1.5 0.4 0.1 0.2 2.2 0.3 0.0 0.6 2.6 6.9 5.3 0.2 0.6 3.6 1.6 0.9 0.1 0.9 NOTCH2 ENSG00000134250 "Notch receptor 2" Q04721 1 119911553-120100779 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048743 Approved Supported "Nucleoplasm,Plasma membrane" NA NA 160000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "HPA048743: AB_2680508" "unprognostic (1.33e-1)" "unprognostic (1.43e-2)" "unprognostic (2.66e-1)" "unprognostic (1.40e-3)" "unprognostic (7.98e-2)" "unprognostic (4.01e-2)" "unprognostic (1.22e-1)" "unprognostic (7.32e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.24e-4)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.86e-2)" "unprognostic (6.12e-3)" "unprognostic (1.55e-2)" "unprognostic (2.65e-2)" "unprognostic (1.12e-2)" "unprognostic (7.35e-3)" 27.1 12.9 16.4 20.4 13.6 13.7 24.8 11.9 16.4 31.0 20.3 16.0 5.4 21.2 20.8 24.9 25.7 18.5 14.2 15.9 13.7 10.9 19.6 20.2 16.7 20.6 18.6 33.9 20.1 12.1 5.5 24.9 13.9 20.4 13.6 19.3 17.1 22.2 6.4 32.3 11.9 26.6 15.7 25.3 10.5 25.4 19.3 15.3 21.2 8.9 17.9 19.0 24.1 14.8 54.2 17.7 27.0 20.7 108.5 92.7 26.6 39.7 54.8 51.8 55.8 16.3 14.2 1.4 32.6 75.3 46.2 20.1 42.8 35.3 82.5 64.0 27.2 32.1 45.7 1.6 40.5 32.7 8.0 75.5 22.5 155.2 103.7 78.4 26.9 14.5 0.8 65.3 63.7 59.2 13.9 9.2 34.6 5.0 19.6 9.1 94.2 36.1 27.3 33.4 1.1 13.4 54.5 50.0 27.9 53.4 28.0 11.7 97.0 67.0 45.8 102.7 63.1 27.9 16.8 16.5 98.7 29.5 65.2 15.0 14.9 22.9 1.4 7.3 1.4 39.0 1.6 0.9 23.7 33.3 3.1 2.0 8.9 2.4 10.5 12.3 3.8 4.4 16.4 13.6 11.9 16.4 15.9 13.7 20.6 18.6 13.9 15.7 19.3 14.8 4.6 35.3 19.5 125.4 36.6 46.3 56.6 14.8 31.3 3.3 38.1 25.3 16.0 24.3 28.5 18.4 6.2 1.6 26.0 6.2 0.0 46.8 17.7 33.8 21.9 5.4 6.1 18.3 4.2 12.9 8.9 67.8 5.1 61.1 15.8 78.3 3.9 41.5 32.7 3.3 22.6 7.9 20.3 74.7 78.2 12.6 55.0 76.6 39.2 43.1 79.3 46.2 15.5 75.4 0.6 26.8 105.5 85.4 14.2 37.2 3.2 4.9 16.4 10.5 19.7 83.6 34.0 10.0 4.3 75.1 88.9 1.6 18.5 22.0 15.8 66.9 NOTCH2NLR ENSG00000286106 "Notch 2 N-terminal like R (pseudogene)" 1 120723946-120793874 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "granulocytes: 10.7;monocytes: 7.5" "Low cell line specificity" "Detected in many" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 18: U-2197 - ECM organization" 2.6 1.0 0.9 1.3 0.9 1.5 1.4 0.5 1.0 1.5 1.7 0.6 0.0 1.4 4.9 2.9 2.2 1.2 1.5 1.0 1.0 0.6 1.3 1.6 0.7 1.4 1.1 0.7 0.3 0.8 1.3 0.8 1.9 1.2 1.0 1.4 1.3 0.2 3.8 0.5 2.3 0.5 1.6 0.6 2.2 1.1 1.1 0.9 0.7 0.7 1.1 1.0 7.2 0.0 1.1 2.1 7.7 4.7 0.0 1.2 1.9 1.7 2.4 1.0 0.1 0.0 3.0 8.5 3.6 2.5 3.5 4.0 2.1 5.3 0.0 3.8 0.0 0.5 2.4 1.5 0.8 2.3 2.1 5.6 7.7 2.5 0.0 0.9 0.6 6.7 8.4 6.8 1.0 2.6 0.1 0.2 3.3 1.1 5.2 2.8 3.9 3.9 0.1 0.0 4.7 4.7 2.4 1.0 0.3 0.8 1.9 1.6 5.8 10.4 2.0 2.5 0.8 1.6 2.5 2.3 0.0 10.7 3.5 4.9 0.7 4.4 1.3 0.6 1.4 1.1 2.0 1.6 1.0 1.1 9.1 1.9 7.5 1.2 0.8 0.5 0.9 0.9 0.5 1.0 1.0 1.0 1.4 1.1 0.8 0.5 1.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 414.2;Skeletal myocytes: 131.6;Smooth muscle cells: 317.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;MCF7: 66.9;RT4: 41.2;U-87 MG: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA 46000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Actin filaments" "CAB005393: AB_2151246, HPA044392: AB_2678926" "unprognostic (4.97e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (9.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.72e-1)" "unprognostic (9.04e-2)" "unprognostic (3.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (3.13e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (3.35e-2)" "unprognostic (8.34e-3)" "unprognostic (4.40e-2)" "unprognostic (2.00e-3)" 85.7 5.3 14.8 10.4 12.4 0.2 50.5 11.0 21.3 49.4 7.1 14.8 5.5 39.9 16.9 74.3 35.8 23.5 43.6 9.5 11.3 26.0 3.2 38.3 9.2 12.0 15.2 18.9 10.7 12.6 10.3 59.8 14.3 22.0 4.2 0.5 24.4 16.5 29.7 82.1 14.3 16.9 8.2 15.0 11.6 3.8 15.8 34.1 32.3 25.1 10.4 26.3 55.1 10.0 13.0 8.1 66.3 30.3 9.2 7.3 29.8 10.2 0.4 0.4 0.3 15.6 13.4 0.4 7.7 18.9 0.1 15.1 12.1 0.2 0.6 0.1 3.1 0.4 12.4 3.5 4.5 0.0 1.2 8.4 7.3 15.5 1.6 0.6 0.8 4.6 0.5 0.6 1.2 66.9 15.9 0.1 38.8 11.2 0.0 0.1 3.7 0.3 0.0 41.2 1.9 21.4 0.1 37.8 0.0 19.6 40.3 0.1 0.0 1.9 21.0 0.3 0.1 0.1 0.7 0.0 45.7 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 14.8 12.4 11.0 21.3 9.5 11.3 12.0 15.2 14.3 8.2 15.8 10.0 39.6 9.6 1.5 5.9 0.4 24.1 7.8 17.8 4.6 0.4 41.5 30.7 60.7 0.0 28.5 16.5 0.0 20.2 1.0 0.0 5.9 14.8 0.5 4.8 13.5 32.0 0.0 0.0 0.6 0.0 3.9 24.2 2.0 11.8 0.0 5.9 4.2 0.0 2.8 0.0 0.3 0.3 6.1 10.4 12.3 0.1 9.0 4.1 17.8 13.1 0.7 0.8 0.0 0.0 0.2 0.9 0.1 11.7 0.0 13.0 0.1 0.0 4.2 0.8 414.2 131.6 317.0 0.9 1.2 72.1 72.2 31.5 2.0 1.2 0.2 36.0 NOTUM ENSG00000185269 "Notum, palmitoleoyl-protein carboxylesterase" Q6P988 17 81952507-81961840 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 135.7" "Cell type enriched" "Detected in some" 45 "Extravillous trophoblasts: 1002.5" "Cancer enhanced" "Detected in many" "stomach cancer: 48.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 428.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022851 Approved "Endoplasmic reticulum" "Secreted in female reproductive system" NA NA 1900000 "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA022851: " "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-2)" "unprognostic (4.80e-3)" "unprognostic (1.97e-1)" "unprognostic (9.02e-3)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (6.49e-2)" "unprognostic (8.72e-2)" "unprognostic (1.40e-1)" "unprognostic (2.01e-2)" "unprognostic (4.48e-6)" "unprognostic (1.76e-1)" "unprognostic (9.88e-2)" "unprognostic (1.22e-3)" "unprognostic (1.00e-1)" 0.0 0.1 1.6 0.0 1.9 0.0 0.2 0.6 1.8 0.2 0.1 0.0 1.1 2.1 0.3 0.3 0.4 0.2 0.3 1.0 1.0 1.2 10.0 2.2 0.0 1.7 2.7 0.1 0.4 0.9 0.2 135.7 1.3 0.3 0.0 0.0 0.6 0.1 8.2 2.2 0.3 0.1 0.9 0.2 2.1 2.8 1.3 0.0 0.0 0.5 0.0 1.4 0.2 0.8 0.0 1.2 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.1 10.0 0.4 0.0 1.8 0.3 0.2 0.4 2.4 0.0 0.0 0.1 1.1 2.2 2.8 428.6 0.2 0.4 0.4 0.2 0.0 0.0 0.0 0.6 0.0 0.2 11.2 0.0 0.0 0.6 0.0 0.2 0.1 67.9 0.4 0.0 0.2 0.1 0.0 0.2 15.7 1.6 4.2 1.7 6.2 2.3 0.1 4.9 0.0 0.5 6.3 0.0 0.2 0.1 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 0.6 1.8 1.0 1.0 1.7 2.7 1.3 0.9 1.3 0.8 0.0 0.0 3.7 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.6 1.3 1.2 0.0 0.0 0.0 0.0 10.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.8 0.0 0.0 0.6 0.0 1002.5 1.2 1.5 0.3 0.0 0.1 0.0 3.6 18.4 0.0 1.1 0.1 0.0 0.0 0.3 0.2 0.3 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.5 12.7 0.0 0.0 22.0 0.1 0.0 0.3 0.0 NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Human disease related genes, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7" "Cell type enhanced" "Detected in some" "Adipocytes: 39.4;Bipolar cells: 56.7;Endothelial cells: 32.0;Excitatory neurons: 21.8;Hepatic stellate cells: 42.5;Horizontal cells: 21.9;Inhibitory neurons: 20.9" "Cancer enriched" "Detected in many" 4 "glioma: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.7;HDLM-2: 11.0;HUVEC TERT2: 16.9;SH-SY5Y: 5.6;TIME: 25.8;U-2 OS: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: AB_10962628" "unprognostic (9.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (3.04e-3)" "unprognostic (1.46e-1)" "unprognostic (6.21e-2)" "unprognostic (2.36e-1)" "unprognostic (3.02e-3)" "unprognostic (6.42e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (5.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-1)" "unprognostic (8.31e-2)" 6.7 1.9 12.4 0.7 15.1 0.0 5.7 0.5 16.7 3.2 0.0 1.8 0.6 3.4 0.6 1.4 2.9 1.4 6.7 16.0 5.8 4.7 1.0 9.3 0.5 4.6 3.0 1.2 1.1 1.0 6.2 3.9 3.6 2.3 0.5 5.6 1.1 0.8 2.3 1.1 1.7 2.0 0.6 1.5 1.5 2.0 4.6 0.4 4.5 2.5 0.2 2.5 2.0 9.8 0.0 0.1 9.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 1.3 0.0 0.0 11.0 0.4 0.0 0.1 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 5.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 15.1 0.5 16.7 16.0 5.8 4.6 3.0 3.6 0.6 4.6 9.8 39.4 0.0 0.0 5.9 0.1 0.6 0.2 0.0 0.6 56.7 0.1 0.5 3.4 1.5 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.1 32.0 0.0 0.0 21.8 0.2 0.0 1.2 0.0 0.1 0.0 0.1 42.5 0.5 0.1 21.9 20.9 0.0 0.0 1.6 1.5 3.5 0.0 0.1 0.0 9.4 0.0 1.3 0.0 11.6 9.5 0.2 0.0 0.4 1.2 0.3 0.0 0.0 0.0 3.3 0.0 0.6 0.6 2.4 2.3 0.3 0.1 0.0 0.5 0.4 0.0 0.3 NPAS3 "bHLHe12, MOP6, PASD6" ENSG00000151322 "Neuronal PAS domain protein 3" Q8IXF0 14 32934396-33820863 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.8" "Group enriched" "Detected in many" 6 "Astrocytes: 3405.1;Inhibitory neurons: 1408.3;Oligodendrocyte precursor cells: 1893.0;Oligodendrocytes: 1772.0" "Group enriched" "Detected in some" 4 "endometrial cancer: 6.4;glioma: 7.7;ovarian cancer: 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "AF22: 9.3;U-266/70: 23.6;U-266/84: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075337 Enhanced Supported Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA075337: " "unprognostic (6.02e-3)" "unprognostic (2.37e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-2)" "unprognostic (3.24e-1)" "unprognostic (1.36e-1)" "unprognostic (1.14e-2)" "unprognostic (5.65e-2)" "unprognostic (2.74e-1)" "unprognostic (3.12e-3)" "unprognostic (5.29e-3)" "unprognostic (1.38e-1)" "unprognostic (3.18e-3)" "unprognostic (2.65e-3)" "unprognostic (1.50e-1)" "unprognostic (2.69e-3)" "unprognostic (3.27e-1)" 0.8 0.8 17.3 0.1 19.9 0.0 0.9 14.6 12.9 6.0 0.0 1.4 0.3 3.9 0.8 0.3 3.9 0.7 0.4 14.0 15.0 0.9 0.1 0.2 0.1 22.8 18.0 2.7 0.4 0.5 1.0 0.5 15.8 0.8 0.3 1.4 0.8 1.3 0.2 0.2 0.4 0.6 18.0 1.1 1.0 1.3 15.9 0.4 1.8 0.2 0.2 0.5 0.5 18.3 0.0 0.0 9.3 0.0 0.2 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.6 23.6 7.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 19.9 14.6 12.9 14.0 15.0 22.8 18.0 15.8 18.0 15.9 18.3 5.1 0.0 0.0 3405.1 0.1 1.0 1.0 0.0 0.6 8.9 3.8 5.1 2.1 0.0 0.1 1.8 0.0 1.5 0.1 0.1 1.9 0.1 22.2 24.6 5.7 3.2 1.2 0.0 341.9 0.0 0.1 3.5 0.0 72.3 0.0 0.7 4.2 0.1 0.5 10.1 1408.3 0.0 0.0 0.0 1.4 17.0 7.2 0.7 0.0 116.2 0.0 7.4 0.0 1893.0 1772.0 0.2 0.0 5.3 0.1 0.5 0.0 0.5 1.8 0.7 0.0 11.5 3.1 0.2 0.8 0.1 0.4 0.3 1.0 1.1 0.0 0.5 NPB "PPL7, PPNPB" ENSG00000183979 "Neuropeptide B" Q8NG41 17 81900745-81902905 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 8.1" "Group enriched" "Detected in many" 6 "Spermatogonia: 41.5;Syncytiotrophoblasts: 97.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.2;PC-3: 3.4;RH-30: 1.8;SH-SY5Y: 2.7;U-2 OS: 2.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (2.44e-2)" "unprognostic (6.21e-2)" "unprognostic (2.90e-1)" "unprognostic (3.47e-3)" "unprognostic (9.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.31e-1)" "unprognostic (1.92e-1)" "unprognostic (3.55e-2)" "unprognostic (5.40e-2)" "unprognostic (5.86e-2)" "unprognostic (1.96e-1)" "unprognostic (6.06e-2)" "unprognostic (3.71e-1)" "unprognostic (4.32e-1)" 0.3 0.1 2.2 0.0 1.8 0.0 0.2 2.6 2.4 0.4 0.0 0.2 0.0 0.3 0.0 0.3 0.3 0.0 0.4 1.5 7.1 0.3 0.8 0.1 0.1 5.2 5.0 0.5 0.1 0.2 0.3 0.2 4.3 0.2 0.0 0.2 0.2 0.1 0.2 0.4 0.5 0.1 3.8 0.4 0.6 1.5 6.2 0.2 0.1 0.0 0.1 0.2 0.3 8.1 0.2 0.8 0.6 0.1 0.1 0.1 0.5 0.3 0.1 0.2 0.0 0.4 0.0 0.2 0.1 0.1 0.4 0.0 0.3 0.1 0.2 2.2 0.0 0.4 0.1 0.0 0.1 0.0 0.2 0.0 0.7 0.2 0.1 0.4 0.0 0.4 0.6 0.0 0.1 0.1 0.0 0.4 0.2 0.1 3.4 0.1 1.8 0.0 0.0 0.2 0.4 2.7 0.2 0.0 0.3 1.0 0.0 0.0 0.2 0.2 2.3 0.0 0.2 0.1 0.2 0.0 0.0 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.8 2.6 2.4 1.5 7.1 5.2 5.0 4.3 3.8 6.2 8.1 1.1 0.0 0.0 1.3 0.4 2.5 0.6 1.8 1.2 1.0 3.3 6.6 0.0 1.5 0.6 0.0 0.0 2.1 0.1 1.2 1.9 0.9 1.5 0.8 3.0 0.9 0.0 0.0 0.4 0.2 3.6 3.3 4.6 0.3 0.0 2.6 1.1 0.2 1.2 0.0 1.2 0.4 0.0 2.6 1.6 3.8 5.0 0.2 5.4 0.0 0.1 0.4 0.0 1.0 4.5 1.8 3.7 2.6 0.2 0.9 0.9 2.1 0.7 1.2 0.0 1.0 3.4 10.7 41.5 1.3 1.1 97.0 0.4 0.5 0.6 0.4 NPC2 "EDDM1, HE1, NP-C2" ENSG00000119655 "NPC intracellular cholesterol transporter 2" P61916 14 74476192-74494177 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "epididymis: 16783.1" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 2034.2;Hofbauer cells: 2898.5;Kupffer cells: 2035.4" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 769.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 668.7;classical monocyte: 1300.7;intermediate monocyte: 1772.7;myeloid DC: 587.8;neutrophil: 674.2;non-classical monocyte: 1252.1;plasmacytoid DC: 2113.2" "Group enriched" "Detected in all" 5 "dendritic cells: 2113.2;granulocytes: 674.2;monocytes: 1772.7" "Cell line enhanced" "Detected in all" "ASC diff: 1619.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000835, CAB032888" Enhanced "Secreted to blood" NA NA 53000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032888: AB_2157036, HPA000835: AB_1079499" "unprognostic (1.27e-3)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.83e-5)" "unprognostic (1.17e-1)" "unprognostic (1.82e-2)" "unprognostic (3.72e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (6.67e-3)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.32e-1)" "unprognostic (3.11e-3)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.97e-1)" "prognostic favorable (6.55e-4)" "unprognostic (1.42e-1)" 260.1 297.0 127.1 261.3 145.4 305.3 221.3 152.2 190.6 284.5 434.0 259.7 201.7 196.7 16783.1 185.0 170.0 356.0 215.1 118.1 156.9 322.4 202.4 786.0 360.3 185.7 145.6 283.1 219.9 241.3 197.5 263.1 179.2 164.2 220.8 48.6 221.9 261.3 58.7 181.6 193.3 180.5 151.1 305.6 206.8 156.8 172.1 134.4 444.7 114.7 241.9 347.4 187.9 195.5 297.2 199.3 124.8 179.4 1619.3 498.6 404.8 194.1 707.1 200.9 398.9 351.7 420.3 78.6 141.6 181.9 372.6 595.9 170.0 405.5 188.6 120.4 126.3 29.6 96.7 296.2 348.6 51.0 548.4 467.7 388.9 173.7 336.9 930.2 298.1 87.0 32.9 601.4 224.0 106.9 70.1 75.9 52.9 489.0 307.9 39.5 219.1 281.6 511.1 735.0 5.5 91.3 296.3 120.3 298.0 359.6 205.2 225.7 268.9 291.9 342.0 396.1 188.2 253.7 452.5 24.2 292.1 168.4 163.4 668.7 1300.7 274.1 92.2 1772.7 87.9 295.2 126.5 92.3 587.8 241.8 120.9 100.5 674.2 99.5 1252.1 2113.2 187.8 1304.5 127.1 145.4 152.2 190.6 118.1 156.9 185.7 145.6 179.2 151.1 172.1 195.5 154.9 381.4 2034.2 11.1 160.2 374.9 557.8 1074.2 170.2 9.9 138.6 220.5 55.4 163.0 626.9 331.1 22.9 228.3 664.0 301.0 305.2 500.4 90.9 123.8 168.5 276.5 119.7 65.4 2.1 279.4 803.3 318.1 61.7 161.0 341.4 104.2 447.3 195.6 2898.5 8.4 3.8 264.8 832.1 2035.4 750.9 69.6 566.7 1462.6 602.9 6.5 790.5 167.4 117.4 7.5 24.4 368.3 405.1 291.9 287.4 357.9 298.1 969.0 393.3 25.1 131.5 118.3 155.9 268.1 166.7 182.6 320.7 210.4 109.9 330.0 298.5 521.6 NPFF FMRFAL ENSG00000139574 "Neuropeptide FF-amide peptide precursor" O15130 12 53506690-53507638 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 84 "epididymis: 820.5" "Cell type enhanced" "Detected in some" "Astrocytes: 11.1;Excitatory neurons: 1.3;Inhibitory neurons: 1.2;Microglial cells: 1.9;Oligodendrocytes: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HHSteC: 13.3" "Region enriched" "Detected in some" 7 "pons and medulla: 11.4" "Region enriched" "Detected in all" 7 "cerebellum: 50.8" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" 0.2 0.4 1.4 0.0 1.4 0.0 0.1 1.4 9.7 0.2 1.4 0.1 0.8 0.0 820.5 0.1 0.1 0.1 0.2 1.4 2.1 0.1 0.1 0.3 0.0 3.4 3.2 0.2 0.1 0.0 0.1 0.0 1.6 0.1 0.0 0.2 0.3 0.3 0.0 0.1 0.1 0.0 3.1 0.1 0.1 0.1 1.8 0.1 0.1 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.5 0.2 0.6 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.1 1.6 0.3 0.0 0.6 0.2 0.0 0.2 0.2 0.4 1.5 0.0 0.0 0.2 0.0 0.5 0.1 1.7 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.4 1.4 9.7 1.4 2.1 3.4 3.2 1.6 3.1 1.8 1.6 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 NPHS1 "CNF, NPHN" ENSG00000161270 "NPHS1 adhesion molecule, nephrin" O60500 19 35825372-35869287 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Myogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "kidney: 41.5;pancreas: 22.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.0;Early spermatids: 13.5;Endometrial ciliated cells: 4.5;Fibroblasts: 5.1;Glandular and luminal cells: 12.1;Late spermatids: 6.9" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.1;JURKAT: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB035555 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "CAB035555: " "unprognostic (3.42e-2)" "unprognostic (1.53e-1)" "unprognostic (1.96e-1)" "unprognostic (3.53e-2)" "unprognostic (1.65e-1)" "unprognostic (2.39e-2)" "unprognostic (6.47e-3)" "unprognostic (2.25e-2)" "unprognostic (1.58e-1)" "unprognostic (1.69e-1)" "unprognostic (3.32e-2)" "unprognostic (3.17e-1)" "unprognostic (3.83e-5)" "unprognostic (4.30e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" 0.3 0.0 0.4 0.6 0.9 0.2 0.0 0.8 0.4 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.2 41.5 0.1 0.0 3.9 0.4 0.4 0.0 22.8 0.0 0.1 0.0 0.5 0.0 0.0 0.7 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.3 0.7 0.6 0.7 0.0 0.0 2.2 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.8 0.4 0.4 0.2 0.4 0.4 0.5 0.1 0.6 0.7 0.3 0.0 0.5 0.0 0.2 0.8 0.8 0.0 0.6 5.0 0.3 0.3 1.0 0.0 0.0 3.7 0.0 0.0 0.2 0.0 0.0 0.3 13.5 4.5 0.4 0.7 0.0 0.0 0.7 2.4 0.0 5.1 0.0 12.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.1 6.9 0.0 2.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 0.4 0.5 0.8 0.4 0.1 0.4 0.0 0.3 0.0 0.1 0.3 NPIPB4 ENSG00000185864 "Nuclear pore complex interacting protein family member B4" C9JG80 16 21834569-21880827 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Astrocytes: 149.5;Early spermatids: 150.6;Excitatory neurons: 255.3;Inhibitory neurons: 182.5;Microglial cells: 391.6;Oligodendrocyte precursor cells: 207.6;Oligodendrocytes: 217.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (3.09e-3)" "unprognostic (3.51e-3)" "unprognostic (4.01e-2)" "unprognostic (1.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-3)" "unprognostic (2.03e-1)" "unprognostic (1.35e-1)" "unprognostic (6.82e-2)" "unprognostic (3.66e-1)" "unprognostic (1.76e-1)" "unprognostic (4.05e-3)" "unprognostic (6.04e-8)" "unprognostic (3.37e-1)" "unprognostic (7.78e-2)" "unprognostic (2.32e-1)" "unprognostic (5.46e-3)" 25.3 18.6 29.4 26.3 11.2 88.8 24.9 45.3 24.1 28.1 0.0 27.0 17.3 20.5 71.0 19.4 27.8 17.6 21.3 12.1 5.1 25.0 30.4 27.6 38.8 8.3 4.6 24.4 22.4 6.6 23.6 14.8 8.9 28.8 27.8 31.2 23.3 11.8 28.5 104.5 36.7 13.0 0.0 41.1 26.5 20.8 14.8 17.3 31.9 7.5 27.1 20.6 24.8 9.0 14.0 18.6 17.3 13.7 12.2 17.3 29.3 16.7 5.1 5.5 8.9 38.6 19.2 27.2 12.4 14.5 5.1 15.5 9.4 14.0 10.9 10.9 8.7 10.5 56.2 53.0 8.0 44.2 26.9 13.0 16.8 14.6 24.3 11.3 12.1 21.2 23.3 22.8 8.4 40.0 16.9 27.7 20.8 4.5 9.9 25.4 10.3 15.3 6.2 13.6 17.2 10.5 11.1 12.8 8.2 16.3 16.9 12.9 26.9 29.1 14.7 14.0 14.7 11.6 11.9 27.8 9.2 20.4 14.0 3.1 0.9 0.3 0.7 0.5 0.6 1.0 1.0 0.5 0.2 2.7 0.8 0.9 1.4 2.2 0.6 2.0 0.2 0.2 29.4 11.2 45.3 24.1 12.1 5.1 8.3 4.6 8.9 0.0 14.8 9.0 7.1 3.2 16.8 149.5 4.3 7.6 1.2 0.9 3.4 5.1 1.3 0.9 2.1 0.0 6.1 0.0 4.2 0.5 7.6 1.7 0.0 1.0 150.6 5.1 5.4 3.6 1.2 4.4 255.3 0.6 0.3 3.6 6.1 8.8 10.8 3.0 1.4 0.8 0.7 1.7 182.5 2.1 2.0 1.2 5.2 25.3 0.3 4.3 0.0 391.6 2.8 1.2 3.1 207.6 217.1 1.4 3.0 0.4 5.9 0.7 1.0 0.1 3.9 6.4 0.0 3.1 3.1 1.5 0.5 2.3 8.4 0.8 7.0 1.8 2.2 0.7 NPIPB5 ENSG00000243716 "Nuclear pore complex interacting protein family member B5" A8MRT5 16 22479121-22536521 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 57.1;Club cells: 50.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA053611 Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA053611: AB_2682206" "unprognostic (7.52e-4)" "unprognostic (2.08e-1)" "unprognostic (2.32e-2)" "unprognostic (9.43e-3)" "unprognostic (3.96e-1)" "unprognostic (2.64e-3)" "unprognostic (2.40e-3)" "unprognostic (4.20e-2)" "unprognostic (1.65e-1)" "unprognostic (4.19e-2)" "unprognostic (1.09e-1)" "unprognostic (3.87e-2)" "unprognostic (1.90e-10)" "unprognostic (1.10e-1)" "unprognostic (3.39e-2)" "unprognostic (3.86e-2)" "unprognostic (3.76e-5)" 58.6 36.5 63.2 66.8 37.2 136.4 58.0 69.0 90.4 67.1 6.8 61.8 36.5 41.8 124.9 41.2 54.9 27.7 50.9 24.8 27.4 49.0 38.4 77.0 82.6 22.1 37.3 57.1 49.4 14.7 50.4 29.3 22.9 58.9 47.3 115.7 56.7 22.8 78.4 212.1 90.9 25.3 2.6 84.6 50.9 41.0 57.1 43.1 75.5 17.7 61.0 45.9 58.8 33.2 31.3 25.7 16.3 23.3 27.8 24.9 35.4 18.9 6.3 11.5 13.9 35.4 53.3 43.9 34.7 17.4 11.3 24.5 41.2 21.3 19.0 53.8 17.2 16.1 85.6 66.1 27.5 83.5 29.1 30.1 20.9 23.0 41.1 20.6 18.3 45.0 43.5 52.8 10.3 57.6 26.6 101.3 46.4 4.9 11.7 44.7 12.1 51.1 18.2 18.9 21.0 14.9 23.3 36.6 19.7 32.9 19.9 30.8 71.4 39.4 17.4 31.2 30.6 35.7 18.9 54.4 15.7 63.6 14.3 6.2 2.7 2.1 3.9 1.2 1.6 6.8 3.8 2.6 1.4 7.7 4.0 3.5 6.0 2.8 2.5 5.2 2.0 1.3 63.2 37.2 69.0 90.4 24.8 27.4 22.1 37.3 22.9 2.6 57.1 33.2 30.0 28.9 57.1 1.0 20.3 14.4 11.2 3.0 17.1 16.5 10.5 7.1 34.8 4.3 50.6 5.5 10.4 5.1 22.8 3.3 0.0 3.8 7.1 19.3 20.5 23.6 1.2 17.2 0.3 1.4 2.8 20.4 22.4 32.7 10.1 21.0 8.2 2.0 4.4 6.7 0.2 3.8 0.0 8.1 16.7 2.8 10.2 25.5 5.4 1.0 14.2 5.5 12.3 0.5 0.3 5.0 4.0 6.4 21.7 13.0 4.3 1.6 31.6 23.8 0.0 32.7 22.7 3.6 2.3 14.0 11.5 5.9 29.7 9.3 3.3 10.3 NPIPB7 "LOC440350, NPIPL1" ENSG00000233232 "Nuclear pore complex interacting protein family member B7" O75200 16 28456372-28471175 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 22.2" "Cell type enriched" "Detected in some" 4 "Early spermatids: 152.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA011188, HPA053611" Approved Approved Nucleoplasm "Secreted in male reproductive system" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA011188: AB_2668455, HPA053611: AB_2682206" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (1.94e-1)" "unprognostic (7.43e-2)" "unprognostic (3.07e-3)" "unprognostic (3.35e-2)" "unprognostic (3.44e-1)" "unprognostic (2.78e-2)" "unprognostic (3.62e-2)" "unprognostic (3.04e-2)" "unprognostic (4.40e-1)" "unprognostic (2.22e-1)" "unprognostic (7.73e-2)" "unprognostic (2.03e-2)" 1.4 0.9 4.0 1.4 4.0 2.6 1.0 6.1 8.2 0.5 0.1 1.4 1.0 1.3 2.1 0.2 0.7 0.3 0.4 4.0 3.0 0.6 1.2 0.8 1.5 3.1 0.7 1.6 1.7 0.4 0.3 0.7 1.9 1.0 1.4 4.5 0.8 1.1 5.0 3.2 1.3 0.7 0.0 1.3 2.4 22.2 2.7 1.0 0.6 1.0 0.6 0.5 0.1 1.7 0.6 4.1 3.0 2.0 1.3 1.3 6.3 1.5 0.1 0.3 0.5 1.5 1.8 3.2 0.9 1.0 0.3 2.0 0.9 0.6 0.2 1.1 1.5 1.2 4.5 3.1 0.6 2.8 6.3 1.4 3.1 1.0 0.9 1.6 0.1 1.9 1.0 2.2 0.7 5.4 0.7 2.9 1.9 0.2 0.2 2.6 1.8 1.6 0.2 1.5 1.6 0.8 1.3 0.5 0.6 2.8 2.2 1.2 2.2 1.1 2.8 1.5 1.0 4.4 2.2 3.1 0.4 1.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 4.0 6.1 8.2 4.0 3.0 3.1 0.7 1.9 0.0 2.7 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 1.8 0.0 0.2 0.0 0.1 0.0 0.0 152.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.8 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 NPLOC4 "FLJ20657, KIAA1499, NPL4" ENSG00000182446 "NPL4 homolog, ubiquitin recognition factor" Q8TAT6 17 81556887-81648465 "Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 164.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 20.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021560, HPA023295" Enhanced Supported Nucleoplasm,Cytosol NA NA 30000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA021560: AB_1854586, HPA023295: AB_1854587" "unprognostic (3.17e-1)" "unprognostic (2.98e-1)" "unprognostic (1.78e-1)" "unprognostic (1.00e-3)" "unprognostic (8.72e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (1.16e-5)" "unprognostic (1.06e-2)" "unprognostic (4.42e-1)" "unprognostic (2.97e-1)" "unprognostic (4.15e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (6.95e-7)" "unprognostic (1.01e-1)" "unprognostic (6.98e-2)" "unprognostic (6.51e-2)" "unprognostic (1.72e-1)" 37.3 46.6 27.2 32.4 27.6 41.7 32.0 22.2 28.3 30.4 27.1 35.2 24.5 35.3 23.5 51.5 28.8 23.3 58.4 26.6 31.2 42.2 54.8 37.9 33.2 31.8 27.2 25.9 36.7 29.7 33.2 27.1 28.5 33.3 21.3 20.1 32.4 22.7 164.3 42.1 34.4 29.3 24.1 42.8 36.8 42.8 28.7 33.4 28.4 55.5 28.8 33.2 31.7 32.8 91.9 118.6 46.2 72.1 56.0 46.0 57.2 74.2 82.3 120.4 110.6 90.7 80.2 67.2 57.9 87.7 87.8 72.5 46.0 62.6 104.5 43.0 60.8 77.5 95.5 81.5 53.4 83.4 95.4 45.8 59.1 113.2 40.1 57.7 124.8 62.0 84.1 99.1 73.6 59.5 113.0 45.2 54.3 45.5 74.0 73.6 73.8 54.4 43.6 86.8 61.6 70.6 92.6 127.4 85.7 87.1 100.1 60.9 89.6 156.1 108.1 86.1 121.4 74.8 57.9 84.0 124.6 55.2 102.9 4.1 20.0 4.4 4.6 4.9 2.8 4.7 3.1 3.7 6.3 3.3 2.8 3.7 5.6 2.8 3.1 4.8 3.2 10.0 27.2 27.6 22.2 28.3 26.6 31.2 31.8 27.2 28.5 24.1 28.7 32.8 19.2 12.8 18.1 24.8 15.3 17.6 16.2 12.7 7.4 24.3 19.5 16.1 44.5 11.5 18.5 20.2 29.2 19.5 22.2 38.9 1.9 19.0 96.2 32.8 19.6 22.2 30.5 20.6 38.0 37.4 21.3 15.9 26.0 38.8 3.8 29.2 27.1 54.3 19.1 20.2 36.4 17.2 8.2 27.3 18.7 79.6 17.7 22.8 12.4 19.7 28.7 19.6 14.4 23.1 38.6 47.2 22.8 12.8 16.5 28.4 22.2 27.9 21.5 33.5 19.7 22.3 18.5 29.7 23.9 15.7 24.2 37.1 16.9 19.3 18.9 28.7 NPNT "EGFL6L, POEM" ENSG00000168743 Nephronectin Q6UXI9 4 105894775-106004027 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 137.0;thyroid gland: 234.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.9;Alveolar cells type 2: 103.7;Club cells: 56.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 104.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 30.9;CAPAN-2: 19.1;HeLa: 32.3;Hep G2: 27.1;MCF7: 24.3;RPTEC TERT1: 37.7;T-47d: 51.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003711, HPA050203" Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to extracellular matrix" NA NA 120000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cell Junctions, Cytosol" "HPA003711: AB_1854591, HPA050203: AB_2681050" "unprognostic (1.24e-1)" "unprognostic (7.93e-2)" "unprognostic (1.59e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (7.85e-3)" "unprognostic (4.78e-4)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "prognostic favorable (8.28e-8)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-2)" 22.8 6.3 9.7 5.6 7.9 0.2 27.0 4.7 8.0 32.4 5.7 24.5 56.1 20.9 22.2 10.9 22.4 30.5 5.2 7.5 14.6 105.0 4.0 137.0 4.5 6.1 31.8 10.9 40.1 1.0 47.4 3.4 9.2 82.9 25.2 2.4 8.9 18.7 4.9 8.2 74.1 14.1 4.4 14.8 14.9 3.1 10.5 14.2 234.5 11.5 5.4 9.7 22.1 6.6 0.0 0.2 0.3 0.6 0.0 0.0 30.9 0.2 0.1 0.0 0.0 14.9 19.1 0.2 0.8 0.2 0.0 1.7 7.4 0.0 0.0 0.0 8.4 0.8 32.3 27.1 0.1 0.0 0.2 3.2 2.4 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.0 24.3 0.4 1.5 0.3 0.1 12.0 0.0 0.1 0.3 37.7 1.6 1.7 0.6 1.8 14.1 0.0 4.1 51.2 1.3 0.0 0.6 0.4 0.5 1.1 0.3 1.1 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 7.9 4.7 8.0 7.5 14.6 6.1 31.8 9.2 4.4 10.5 6.6 5.2 185.9 103.7 15.3 0.0 1.9 5.2 13.1 1.8 1.1 22.2 7.0 2.5 27.1 56.4 33.1 0.0 2.4 0.7 5.9 1.9 24.7 11.0 1.0 1.5 18.4 15.6 0.0 1.0 2.5 0.2 8.3 1.1 1.9 0.0 3.3 2.9 0.3 0.3 0.0 10.0 10.6 4.1 0.0 1.5 15.4 2.5 0.6 5.4 14.0 0.0 0.0 0.0 2.0 0.3 7.5 3.4 0.0 0.0 28.4 19.6 4.3 6.4 0.2 0.0 1.9 26.4 2.4 2.0 3.6 1.1 1.5 0.3 1.5 11.0 5.7 NPPA "ANP, PND" ENSG00000175206 "Natriuretic peptide A" P01160 1 11845709-11848345 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hormone, Vasoactive, Vasodilator" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 873 "heart muscle: 60060.6" "Cell type enriched" "Detected in some" 23 "Cardiomyocytes: 62235.0" "Cancer enriched" "Detected in some" 9 "glioma: 7.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 9.6;SH-SY5Y: 9.5" "Region enriched" "Detected in some" 7 "olfactory bulb: 22.8" "Low region specificity" "Detected in all" "HPA058269, HPA064007" Enhanced "Secreted to blood" NA NA 1200000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA058269: AB_2683660, HPA064007: " "unprognostic (1.27e-3)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.94e-1)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (2.01e-1)" "unprognostic (1.48e-1)" "unprognostic (3.25e-2)" "unprognostic (9.72e-3)" "unprognostic (2.21e-1)" "unprognostic (5.93e-4)" "unprognostic (2.31e-1)" "unprognostic (1.59e-1)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" 8.3 3.0 1.7 0.7 2.1 0.6 18.0 1.8 2.4 1.2 2.3 5.0 0.2 3.3 12.9 2.8 1.3 0.9 60060.6 2.2 1.5 2.6 5.0 58.1 1.2 1.7 1.5 12.1 68.7 0.9 3.9 5.9 1.4 5.1 0.0 0.4 28.5 0.0 8.9 5.8 6.1 0.7 1.3 3.1 3.6 3.9 1.7 0.5 7.1 0.0 0.0 1.2 3.9 2.0 0.5 0.2 0.3 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.9 0.6 0.8 0.0 0.0 0.4 1.0 0.0 0.0 0.0 0.2 0.4 1.0 0.3 1.8 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 1.2 0.0 0.3 0.3 1.0 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.6 9.6 9.5 0.0 0.0 0.5 0.3 0.3 0.1 0.0 0.4 0.7 0.6 0.1 0.4 0.8 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 2.1 1.8 2.4 2.2 1.5 1.7 1.5 1.4 1.3 1.7 2.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62235.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 339.1 0.0 0.0 0.3 0.0 0.0 2684.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 636.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPPB ENSG00000120937 "Natriuretic peptide B" P16860 1 11857464-11858945 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Hormone, Vasoactive, Vasodilator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 767 "heart muscle: 5154.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 351.7;Ductal cells: 266.6;Pancreatic endocrine cells: 86.2" "Cancer enhanced" "Detected in some" "testis cancer: 2.2" "Group enriched" "Detected in some" 4 "basal ganglia: 3.4;cerebral cortex: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 135.5;CACO-2: 362.2;SuSa: 67.7" "Region enhanced" "Detected in single" "pons and medulla: 1.4" HPA077324 Approved Vesicles,Cytosol "Secreted to blood" NA NA 9680 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" Vesicles Cytosol "HPA077324: " "unprognostic (3.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.49e-1)" "unprognostic (4.23e-1)" "unprognostic (3.28e-2)" 1.0 0.3 0.3 0.1 3.4 0.0 0.7 0.4 1.8 0.3 0.1 0.3 0.0 0.3 0.3 0.2 0.0 0.6 5154.6 0.3 0.3 0.3 0.5 6.7 0.9 0.3 0.4 0.8 4.0 0.1 0.5 0.8 0.3 0.5 0.0 0.1 1.2 0.0 0.8 0.5 0.4 0.0 0.6 0.1 0.7 0.8 0.5 0.1 0.5 0.0 0.0 0.2 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.0 135.5 0.3 0.0 2.1 1.1 362.2 0.0 0.0 0.1 0.1 0.3 3.8 0.1 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.2 0.1 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.2 0.1 0.4 0.2 0.0 67.7 0.0 0.0 0.0 0.0 32.0 0.2 0.2 0.0 0.1 0.0 0.1 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 0.4 1.8 0.3 0.3 0.3 0.4 0.3 0.6 0.5 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 351.7 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 266.6 0.1 0.8 0.1 4.9 0.0 0.0 0.2 8.3 2.2 11.7 0.0 1.4 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 2.0 0.2 0.0 0.0 0.0 86.2 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 17.6 5.8 0.1 0.0 0.0 3.4 0.0 0.0 0.0 0.1 NPPC CNP ENSG00000163273 "Natriuretic peptide C" P23582 2 231921809-231926396 "Predicted secreted proteins, Transporters" Osteogenesis "Hormone, Vasoactive" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 33.5" "Group enriched" "Detected in many" 8 "Basal squamous epithelial cells: 190.1;Skeletal myocytes: 264.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "medulla oblongata: 33.5;spinal cord: 30.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.4;NTERA-2: 3.9;SCLC-21H: 5.5;SK-MEL-30: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "medulla oblongata: 15.5;spinal cord: 12.5" HPA035362 Uncertain "Secreted to blood" NA NA 6140 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "HPA035362: AB_10671103" "unprognostic (9.70e-2)" "unprognostic (4.45e-2)" "unprognostic (1.99e-1)" "unprognostic (1.06e-2)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.83e-1)" "unprognostic (3.22e-3)" "unprognostic (9.81e-3)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" "unprognostic (4.06e-2)" "unprognostic (1.17e-1)" "unprognostic (6.58e-2)" "unprognostic (1.18e-1)" "unprognostic (3.72e-1)" "unprognostic (1.91e-1)" 0.3 0.1 0.8 2.1 0.9 1.3 0.7 2.8 3.4 1.3 0.0 4.1 0.1 0.6 0.0 3.2 2.6 0.0 5.3 2.0 3.9 0.2 0.0 0.0 1.4 33.5 4.4 1.3 0.1 0.0 2.7 0.2 4.8 4.3 0.2 2.4 1.1 0.4 0.7 0.6 0.9 0.5 30.9 0.4 2.4 0.2 4.6 2.9 0.5 0.1 2.0 0.2 0.4 6.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 1.0 0.0 3.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.5 0.3 0.2 0.2 26.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 2.8 3.4 2.0 3.9 33.5 4.4 4.8 30.9 4.6 6.5 2.1 0.0 0.0 0.7 1.3 3.4 27.1 5.9 190.1 1.1 6.5 18.3 1.9 0.0 0.1 11.0 10.4 0.2 0.6 4.2 0.0 1.1 0.3 3.6 1.3 1.6 3.5 0.0 0.0 0.0 0.0 10.9 5.6 4.8 0.0 0.3 0.0 0.0 0.1 0.0 1.5 3.2 0.0 0.0 1.7 0.0 0.3 1.6 1.8 0.0 2.5 15.2 0.0 0.0 1.3 0.8 3.1 0.0 5.8 11.5 0.0 0.0 0.0 4.1 0.0 264.2 2.0 1.2 7.0 13.2 1.1 0.3 1.7 0.0 2.9 3.1 NPS ENSG00000214285 "Neuropeptide S" P0C0P6 10 127549309-127553540 "Predicted secreted proteins" Neuropeptide "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "head and neck cancer: 4.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "midbrain: 5.4;pons and medulla: 5.1" "Group enriched" "Detected in some" 6 "cerebral cortex: 4.8;white matter: 2.2" CAB020139 Uncertain "Secreted in brain" NA NA "CAB020139: AB_776718" "unprognostic (2.83e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPTX1 ENSG00000171246 "Neuronal pentraxin 1" Q15818 17 80466834-80477843 "Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 107.8;intestine: 31.6" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 175.2;Excitatory neurons: 88.6;Late spermatids: 44.8" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 32.0;HeLa: 26.0;SiHa: 40.7;U-138 MG: 85.2;WM-115: 120.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 55.3;cerebellum: 128.1;cerebral cortex: 102.2;hippocampal formation: 131.3" HPA077062 Enhanced Approved "Secreted in brain" NA NA 1100000 "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA077062: AB_2732329" "unprognostic (2.37e-2)" "unprognostic (1.18e-1)" "unprognostic (1.81e-2)" "unprognostic (6.95e-2)" "unprognostic (4.16e-3)" "unprognostic (2.43e-2)" "unprognostic (1.48e-2)" "unprognostic (3.63e-1)" "unprognostic (1.31e-2)" "unprognostic (2.07e-1)" "unprognostic (1.81e-2)" "unprognostic (9.63e-3)" "unprognostic (1.05e-6)" "unprognostic (1.41e-4)" "unprognostic (1.35e-1)" "unprognostic (8.86e-6)" "unprognostic (2.71e-3)" 0.4 5.1 95.2 1.0 88.8 0.1 0.4 77.7 94.5 0.2 0.0 31.6 0.7 0.8 2.2 0.8 0.8 1.2 0.0 107.8 0.7 0.2 0.0 1.3 0.9 20.1 1.0 0.6 0.2 0.0 2.4 1.2 1.7 0.7 2.1 13.0 0.0 2.5 2.7 3.2 4.2 0.8 3.5 2.1 3.9 1.2 1.3 11.9 0.1 0.6 0.1 0.6 0.1 81.3 0.0 2.0 0.5 0.2 0.4 0.5 0.0 2.0 0.0 0.1 0.0 0.7 0.2 0.0 0.3 0.2 3.5 0.1 32.0 0.0 0.0 0.0 20.2 0.0 26.0 0.1 0.1 0.0 1.4 0.0 0.0 1.3 0.3 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.2 0.0 6.5 0.0 0.0 8.3 0.0 0.0 21.4 0.0 40.7 0.1 0.0 0.3 0.1 0.6 0.3 85.2 0.0 4.2 0.2 0.0 0.0 0.0 0.2 0.0 120.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 95.2 88.8 77.7 94.5 107.8 0.7 20.1 1.0 1.7 3.5 1.3 81.3 1.3 0.0 0.0 8.1 0.3 1.5 0.1 0.0 0.0 12.8 0.7 2.2 3.0 0.0 0.6 0.0 175.2 0.1 0.6 0.3 0.0 0.0 8.2 0.3 0.4 1.2 0.0 0.0 88.6 0.0 0.2 0.9 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 11.0 0.7 0.0 0.0 0.0 44.8 0.9 0.6 0.0 6.5 0.0 0.8 0.0 5.0 5.8 0.6 0.0 2.2 0.1 0.5 0.0 0.0 0.0 4.1 0.0 1.6 1.1 1.6 0.4 0.1 3.0 0.1 0.1 0.5 0.1 0.0 NPTX2 ENSG00000106236 "Neuronal pentraxin 2" P47972 7 98617285-98629869 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 135.8;pituitary gland: 210.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 93.5;Peritubular cells: 326.1;Sertoli cells: 151.2;Spermatocytes: 85.2;Spermatogonia: 94.8" "Cancer enhanced" "Detected in all" "renal cancer: 41.7" "Region enhanced" "Detected in all" "cerebral cortex: 135.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "LHCN-M2: 717.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB020801, HPA049799, HPA058320" Enhanced Approved "Golgi apparatus,Actin filaments,Centrosome" "Secreted to blood" NA NA 2490000 360000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Actin filaments" Centrosome "CAB020801: , HPA049799: AB_2680889, HPA058320: AB_2732621" "unprognostic (1.18e-1)" "unprognostic (9.61e-2)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (1.91e-3)" "unprognostic (9.20e-2)" "unprognostic (2.42e-2)" "unprognostic (6.04e-3)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (7.64e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (5.46e-9)" "unprognostic (1.06e-2)" "unprognostic (1.21e-1)" "unprognostic (5.33e-2)" "unprognostic (3.69e-2)" 7.0 39.2 11.2 1.9 13.6 0.5 3.8 10.1 135.8 9.9 2.5 15.3 0.5 5.7 3.5 3.0 2.8 1.1 9.8 39.2 47.3 1.1 2.6 0.9 0.1 13.8 14.5 3.7 21.4 0.6 210.8 0.1 16.2 7.2 0.8 4.7 3.7 1.6 8.9 8.2 5.4 2.5 6.4 13.0 6.7 34.3 45.6 0.5 3.1 6.7 0.3 5.5 6.9 16.8 0.0 0.0 6.5 0.2 0.0 0.5 0.0 8.8 0.0 0.1 0.0 0.0 0.0 0.0 21.1 2.8 1.5 0.0 0.9 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 717.9 0.0 5.7 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 33.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.5 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.2 13.6 10.1 135.8 39.2 47.3 13.8 14.5 16.2 6.4 45.6 16.8 8.6 0.0 0.6 2.9 0.3 3.8 0.5 0.0 0.0 19.9 0.2 1.4 3.4 5.7 1.3 0.0 4.2 0.0 1.0 4.5 0.0 5.4 12.0 8.5 1.8 16.9 16.0 0.0 22.1 12.8 0.2 11.1 1.5 10.5 0.0 93.5 3.9 0.7 0.5 0.0 5.3 1.2 0.0 0.0 5.4 24.2 14.0 1.3 12.4 5.6 0.0 1.6 0.0 1.0 1.8 2.9 1.1 326.1 1.0 5.2 0.5 0.1 0.0 2.8 151.2 57.2 27.1 85.2 94.8 0.1 3.0 0.1 0.8 12.7 2.3 1.2 NPTXR ENSG00000221890 "Neuronal pentraxin receptor" O95502 22 38818452-38844028 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "brain: 280.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 18.0;Excitatory neurons: 41.7;Inhibitory neurons: 50.4;Oligodendrocyte precursor cells: 19.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 280.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 23.3;SCLC-21H: 30.8;SiHa: 23.6;U-87 MG: 87.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001079 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 420000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" Nucleoplasm "HPA001079: AB_1078414" "unprognostic (6.29e-2)" "prognostic favorable (3.93e-4)" "unprognostic (6.82e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.55e-2)" "unprognostic (6.93e-2)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-2)" "unprognostic (1.71e-1)" "unprognostic (1.52e-3)" "unprognostic (1.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.49e-2)" "unprognostic (9.22e-2)" "unprognostic (8.65e-2)" "unprognostic (2.77e-2)" 2.7 5.0 91.6 1.9 75.4 0.3 2.8 0.3 145.7 8.7 0.0 9.5 1.3 10.9 3.8 3.0 7.9 2.0 15.7 280.2 17.0 1.6 1.9 1.9 1.6 4.1 15.2 8.1 5.2 7.0 6.8 0.4 0.7 8.1 1.5 5.3 4.8 7.0 0.6 1.1 3.3 7.6 3.1 2.5 5.0 1.8 58.0 0.7 2.7 2.5 1.5 7.3 4.8 46.0 1.0 6.2 0.2 1.8 12.2 1.2 0.0 4.1 0.9 7.9 2.7 6.2 1.3 0.0 7.2 1.1 23.3 0.8 1.7 0.2 2.6 0.6 2.0 0.0 0.2 9.6 1.2 0.1 0.3 3.9 0.4 7.2 0.1 11.4 0.3 0.1 7.7 0.3 0.3 9.7 0.0 0.5 7.3 3.0 2.2 1.6 0.0 15.3 2.0 17.1 30.8 2.0 23.6 0.1 0.7 1.7 9.9 2.5 0.4 14.1 8.4 0.0 0.7 2.1 0.0 0.0 87.9 18.5 7.4 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 91.6 75.4 0.3 145.7 280.2 17.0 4.1 15.2 0.7 3.1 58.0 46.0 4.7 0.0 0.0 9.4 0.3 1.1 2.7 0.9 0.0 6.6 3.3 1.5 18.0 4.3 3.0 3.7 2.1 0.0 2.3 0.0 0.0 7.3 1.7 1.7 3.2 4.2 1.8 0.0 41.7 3.8 0.0 1.5 0.5 3.0 0.0 1.5 5.0 0.4 0.2 0.0 50.4 0.2 6.1 0.3 0.9 0.8 1.8 0.3 1.8 1.9 0.0 4.8 6.2 19.1 10.5 2.0 0.0 2.2 0.9 3.8 0.1 0.5 2.2 3.3 0.0 2.4 2.8 0.2 1.3 0.1 1.0 0.0 1.7 0.3 0.0 3.4 NPVF "C7orf9, RFRP" ENSG00000105954 "Neuropeptide VF precursor" Q9HCQ7 7 25224570-25228486 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 62 "retina: 220.5" "Cell type enriched" "Detected in some" 40 "Muller glia cells: 526.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "hypothalamus: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 18 "hypothalamus: 6.1" "Region enriched" "Detected in single" 8 "hypothalamus: 3.0" HPA041733 Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 5: Muller glia cells - Visual perception" "HPA041733: AB_10794524" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 220.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 526.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPW PPL8 ENSG00000183971 "Neuropeptide W" Q8N729 16 2009926-2020755 "Predicted intracellular proteins, Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 10.6" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 188.1;Enteroendocrine cells: 158.5" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 6 "NB-4: 43.5;PC-3: 35.6;RPMI-8226: 74.7;SCLC-21H: 118.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 2.2" HPA064874 Approved "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" "HPA064874: AB_2685378" "unprognostic (7.54e-2)" "unprognostic (4.45e-3)" "unprognostic (3.20e-1)" "unprognostic (4.31e-3)" "unprognostic (8.85e-2)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-1)" "unprognostic (3.06e-1)" "unprognostic (2.20e-2)" "unprognostic (6.26e-3)" "unprognostic (2.37e-1)" "unprognostic (1.81e-5)" "unprognostic (6.53e-3)" "unprognostic (1.26e-1)" "unprognostic (4.41e-1)" "unprognostic (3.43e-2)" 0.4 0.1 1.0 0.4 0.7 1.2 0.1 0.6 3.6 1.1 1.1 0.5 0.6 1.1 1.3 0.4 0.6 0.0 0.1 0.7 1.9 0.4 10.6 0.1 0.2 0.7 0.9 0.4 0.4 0.0 2.7 0.1 0.7 0.3 0.1 0.0 0.1 0.2 0.0 1.7 0.2 0.2 0.5 0.7 2.4 1.2 2.5 0.0 0.2 0.0 0.4 0.2 0.6 1.0 0.4 1.7 0.2 2.5 0.4 0.0 0.7 0.9 0.2 0.5 1.0 3.8 1.5 0.4 0.1 0.8 0.6 0.8 1.1 0.3 0.5 1.8 2.9 0.1 3.0 1.7 2.3 0.4 0.1 1.0 1.3 0.9 1.9 0.1 0.0 2.5 10.8 1.7 0.1 0.9 0.4 43.5 1.9 1.5 35.6 10.5 0.0 74.7 0.4 0.0 118.8 9.9 1.3 2.2 0.3 0.6 5.6 4.4 1.7 0.3 0.6 0.5 0.1 3.6 1.1 1.1 0.6 0.9 0.4 1.2 0.7 0.7 0.2 0.4 0.6 0.4 0.1 0.0 0.7 0.4 0.2 0.1 1.5 0.6 0.2 0.4 0.4 0.2 1.0 0.7 0.6 3.6 0.7 1.9 0.7 0.9 0.7 0.5 2.5 1.0 2.5 0.0 0.0 0.0 2.9 2.0 3.2 1.9 4.0 1.5 2.7 7.1 0.3 0.0 2.0 0.0 0.0 1.2 0.1 6.0 0.0 0.5 0.9 9.9 188.1 4.4 158.5 12.2 0.4 0.2 0.9 14.0 15.8 8.5 8.9 0.5 0.7 35.9 2.3 0.0 0.7 35.8 0.0 0.3 0.3 2.1 2.1 1.6 3.6 0.0 0.1 0.0 0.0 0.0 0.1 2.1 12.4 2.2 1.5 11.9 3.2 0.8 0.3 0.3 0.0 0.5 2.7 8.8 35.4 4.1 2.3 1.6 2.3 1.6 3.9 4.6 NPY PYY4 ENSG00000122585 "Neuropeptide Y" P01303 7 24284188-24291862 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Neuropeptide "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "adrenal gland: 122.6;brain: 423.9;prostate: 332.8" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 56.7;Prostatic glandular cells: 100.6" "Cancer enriched" "Detected in many" 187 "prostate cancer: 1214.9" "Region enriched" "Detected in all" 7 "hypothalamus: 423.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 34 "SH-SY5Y: 700.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016733, CAB034368, HPA036636, HPA044572, HPA056798" Supported Supported Enhanced "Golgi apparatus" "Secreted to blood" NA NA 30700000 21000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 35: Glandular cells - Unknown function" "Golgi apparatus" "CAB016733: , CAB034368: AB_2298657, HPA036636: , HPA044572: AB_2678996, HPA056798: AB_2630371" "unprognostic (2.00e-1)" "prognostic unfavorable (5.78e-4)" "unprognostic (4.15e-1)" "unprognostic (3.76e-2)" "unprognostic (1.59e-2)" "unprognostic (1.87e-1)" "unprognostic (6.30e-2)" "unprognostic (1.24e-2)" "unprognostic (1.78e-1)" "unprognostic (2.52e-1)" 1.8 122.6 32.8 12.8 59.0 5.6 2.2 11.0 39.1 1.3 11.3 2.9 9.7 0.3 0.3 2.3 0.5 1.1 0.8 31.7 423.9 0.5 0.2 0.3 0.0 24.2 25.1 0.5 8.8 0.1 4.7 0.0 15.2 332.8 1.9 4.4 0.3 3.9 0.2 0.2 13.1 1.2 18.8 0.0 8.8 1.1 29.2 0.2 0.9 0.2 0.0 1.4 23.8 33.1 0.0 0.0 2.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.5 1.4 2.0 0.0 0.2 20.5 0.0 0.6 0.0 0.0 0.8 700.2 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 59.0 11.0 39.1 31.7 423.9 24.2 25.1 15.2 18.8 29.2 33.1 0.0 0.0 0.0 2.0 0.5 0.1 1.3 0.0 0.0 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.1 13.4 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 56.7 0.0 0.0 0.0 0.0 16.1 0.3 0.7 1.8 1.0 0.0 0.8 0.0 2.0 1.9 0.3 0.0 0.4 0.0 100.6 0.0 0.0 0.0 0.7 0.0 15.6 0.3 2.4 2.8 0.0 0.0 5.1 0.3 0.0 0.0 2.0 NPY1R NPYR ENSG00000164128 "Neuropeptide Y receptor Y1" P25929 4 163323962-163344832 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 119.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 32.8;Excitatory neurons: 39.8;Hepatic stellate cells: 160.6;Sertoli cells: 46.0;Smooth muscle cells: 34.1" "Cancer enriched" "Detected in many" 13 "breast cancer: 65.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "HEL: 128.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "prognostic favorable (7.68e-5)" "unprognostic (9.14e-3)" "unprognostic (1.55e-1)" "unprognostic (5.09e-2)" "unprognostic (2.60e-1)" "unprognostic (9.29e-2)" "unprognostic (5.28e-3)" "unprognostic (2.26e-1)" "unprognostic (4.14e-2)" "unprognostic (2.50e-1)" "unprognostic (1.89e-2)" "unprognostic (5.92e-2)" "unprognostic (7.39e-2)" "unprognostic (1.92e-3)" "unprognostic (5.48e-2)" "unprognostic (1.74e-1)" "unprognostic (2.21e-1)" 30.5 31.0 10.4 2.9 13.1 0.0 32.4 0.0 13.7 7.8 0.0 5.8 1.0 7.3 10.2 1.8 8.4 4.5 4.8 9.1 19.7 32.3 14.7 2.1 17.3 0.3 0.8 2.8 28.7 3.6 3.0 5.2 0.4 2.5 4.5 4.4 21.4 8.3 2.9 9.8 1.5 5.7 5.7 119.6 1.8 4.1 2.2 1.1 7.9 2.6 0.9 1.8 4.9 9.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.0 0.0 7.0 0.0 0.0 0.0 0.0 128.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.9 0.0 0.1 0.4 0.0 0.0 1.2 0.0 4.6 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.1 0.0 0.0 0.4 3.0 0.0 0.0 0.1 1.2 0.0 0.6 0.1 0.0 0.0 1.4 0.0 4.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 10.4 13.1 0.0 13.7 9.1 19.7 0.3 0.8 0.4 5.7 2.2 9.0 2.1 0.0 0.5 1.3 0.7 2.8 0.7 0.0 3.4 11.6 19.2 3.3 0.9 1.5 0.0 0.0 2.1 0.0 0.0 3.4 13.7 12.5 5.0 0.0 0.4 10.8 32.8 0.0 39.8 0.0 0.0 5.1 0.0 0.1 0.0 3.7 160.6 0.9 0.1 0.0 18.8 1.6 0.0 7.2 0.9 2.4 11.5 0.1 5.4 4.7 0.0 1.1 0.0 2.0 1.4 0.1 15.9 0.4 0.0 0.5 0.1 0.1 0.0 2.1 46.0 1.1 34.1 0.5 0.6 0.1 1.7 0.0 0.6 0.5 2.1 0.3 NQO2 "DHQV, DIA6, NMOR2, QR2" ENSG00000124588 "N-ribosyldihydronicotinamide:quinone reductase 2" P16083 6 2987987-3019755 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 202.5;Proximal tubular cells: 730.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 240.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021283, HPA021332" Enhanced Supported Nucleoplasm,Cytosol NA NA 6000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA021283: AB_1854600, HPA021332: AB_1854601" "unprognostic (7.11e-3)" "unprognostic (1.43e-3)" "unprognostic (2.41e-1)" "unprognostic (3.01e-2)" "unprognostic (1.00e-2)" "unprognostic (3.58e-1)" "prognostic unfavorable (8.40e-4)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (4.90e-2)" "unprognostic (6.59e-2)" "unprognostic (3.60e-2)" "unprognostic (8.28e-2)" "unprognostic (2.03e-1)" "unprognostic (3.32e-2)" "unprognostic (3.96e-1)" "unprognostic (2.02e-1)" 60.0 121.5 48.1 27.0 48.8 72.1 45.0 61.1 65.4 32.6 64.3 28.2 35.3 25.8 32.9 32.8 30.0 31.5 76.5 48.5 49.6 190.3 124.2 30.4 19.5 61.8 47.9 29.8 42.6 33.5 21.2 28.6 61.4 28.1 19.6 31.1 61.9 28.9 123.6 50.7 35.6 19.8 42.9 39.3 36.1 18.2 51.5 18.3 26.8 144.9 18.2 31.8 29.0 53.2 45.7 75.7 42.1 95.3 73.0 42.9 45.4 40.5 51.2 37.1 40.9 80.0 16.1 36.9 144.7 71.1 86.4 33.7 45.4 28.5 28.9 95.9 37.1 23.6 83.0 77.3 59.7 24.4 73.9 27.8 34.2 44.9 40.9 53.4 36.8 47.9 142.3 24.1 30.8 95.5 27.0 44.4 54.9 87.6 59.8 49.3 50.1 108.2 56.6 24.0 11.4 15.9 59.5 25.9 128.9 75.0 35.4 16.9 60.7 34.8 14.4 45.9 18.1 45.4 116.7 12.3 43.3 69.5 72.7 25.2 91.8 52.8 33.1 64.2 24.4 12.1 29.6 29.8 61.7 9.1 17.8 19.6 240.2 30.0 60.8 6.5 37.2 43.2 48.1 48.8 61.1 65.4 48.5 49.6 61.8 47.9 61.4 42.9 51.5 53.2 30.3 9.6 16.1 9.8 16.3 35.2 41.5 32.7 12.5 34.8 34.2 32.1 72.8 47.1 21.3 25.8 10.4 42.6 18.2 21.2 162.4 29.1 51.6 15.1 21.4 28.0 4.8 43.8 47.0 63.4 53.9 51.5 33.1 9.0 13.9 11.0 25.7 202.5 76.6 42.1 46.7 23.3 30.5 44.7 105.7 62.8 35.8 75.4 67.6 19.7 148.6 54.0 20.6 10.6 9.1 55.8 18.3 41.0 15.0 38.6 103.7 730.3 28.7 22.5 26.3 35.0 42.9 24.8 11.4 35.4 41.2 31.2 20.8 21.9 25.4 41.8 NR1H3 "LXR-a, LXRa, RLD-1" ENSG00000025434 "Nuclear receptor subfamily 1 group H member 3" Q13133 11 47248300-47269033 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 66.6;Hofbauer cells: 54.4;Kupffer cells: 100.9;Proximal enterocytes: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 13.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 45.3;HSkMC: 61.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036443, CAB037109" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB037109: AB_1840991, HPA036443: AB_10966142" "unprognostic (2.95e-3)" "unprognostic (5.31e-3)" "unprognostic (5.19e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.19e-1)" "unprognostic (2.65e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.51e-1)" "unprognostic (1.76e-1)" "unprognostic (7.73e-2)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (3.56e-1)" "unprognostic (4.42e-2)" "unprognostic (2.84e-1)" "prognostic favorable (3.40e-4)" 60.7 19.9 11.3 19.4 11.8 3.3 51.1 11.2 14.3 25.3 10.2 24.6 48.4 13.6 17.6 7.6 20.3 19.6 18.5 10.3 11.1 23.4 83.8 24.1 46.7 11.0 12.1 15.2 16.7 6.8 7.2 25.4 11.7 19.4 12.0 2.2 14.8 11.5 9.1 11.7 41.0 7.9 10.5 53.2 16.3 21.8 13.8 11.0 20.3 6.3 13.6 22.4 17.5 11.5 3.5 13.8 6.4 6.1 41.0 45.3 31.1 3.5 17.9 5.7 8.8 17.0 43.2 6.1 6.5 2.8 2.1 9.2 7.6 6.1 3.8 5.8 6.1 8.3 18.7 26.1 17.5 2.9 1.0 61.2 3.7 8.7 5.5 9.7 5.0 9.4 10.2 2.5 4.5 14.8 5.8 17.0 7.1 18.7 4.5 8.4 8.3 4.1 5.0 31.9 6.1 2.3 12.2 7.9 10.4 6.1 19.5 8.8 1.3 4.5 6.1 9.1 2.0 11.9 18.3 7.6 8.2 3.9 2.2 7.8 2.7 2.5 1.4 13.3 1.9 1.0 1.5 1.3 4.3 0.7 1.7 1.4 1.6 5.8 4.2 0.7 3.8 1.9 11.3 11.8 11.2 14.3 10.3 11.1 11.0 12.1 11.7 10.5 13.8 11.5 27.2 0.0 11.3 8.1 3.0 3.3 8.6 4.6 2.2 2.4 12.7 12.1 6.6 15.7 4.9 5.5 2.1 11.0 1.5 24.4 11.7 5.8 31.0 2.4 15.3 12.5 1.8 7.0 9.2 8.7 13.3 14.1 17.9 2.8 13.3 7.1 24.7 66.6 54.4 1.7 10.9 14.6 2.0 100.9 3.3 49.0 9.0 24.7 3.6 1.0 5.4 4.4 2.1 3.0 5.6 4.2 10.7 6.0 2.4 4.1 69.5 26.1 2.5 0.8 19.7 7.4 16.3 32.4 16.8 3.0 2.4 6.6 2.1 5.4 19.0 6.3 NR1H4 "FXR, HRR-1, HRR1, RIP14" ENSG00000012504 "Nuclear receptor subfamily 1 group H member 4" Q96RI1 12 100473708-100564414 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Disease variant, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 39.1;liver: 120.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 92.9;Hepatocytes: 105.1;Proximal enterocytes: 331.0;Proximal tubular cells: 153.8" "Group enriched" "Detected in some" 11 "liver cancer: 18.7;renal cancer: 12.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 30 "Hep G2: 28.3;HHSteC: 14.1;RPTEC TERT1: 44.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA047699 Approved Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA047699: AB_10965320" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (6.68e-2)" "unprognostic (2.49e-1)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (2.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.16e-1)" "unprognostic (2.43e-1)" "unprognostic (3.77e-3)" 0.2 22.6 0.1 1.4 0.1 0.4 1.0 0.5 0.4 0.2 1.8 8.3 29.6 0.1 0.1 0.2 0.2 12.6 0.4 0.2 0.1 28.2 120.6 0.4 0.3 0.1 0.1 14.0 3.1 0.0 1.4 0.0 0.1 0.3 1.6 0.3 0.3 0.0 0.3 0.5 39.1 0.8 0.0 0.4 0.5 0.7 0.2 0.1 0.3 0.1 0.2 6.5 0.1 0.5 0.0 0.9 0.1 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 28.3 14.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.6 0.1 0.0 0.0 44.9 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 92.9 0.0 22.0 0.0 0.0 0.0 8.0 43.0 11.5 0.7 0.0 0.0 0.3 0.0 2.7 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.6 8.9 105.1 0.0 0.0 1.6 17.0 0.0 3.5 0.0 2.0 0.9 0.8 0.0 1.0 0.0 0.0 0.0 0.5 0.3 0.4 19.9 0.0 0.0 0.0 331.0 153.8 0.0 0.0 0.0 0.0 0.1 0.4 1.3 0.0 0.0 0.0 0.9 1.1 30.4 3.7 NR2C1 "TR2, TR2-11" ENSG00000120798 "Nuclear receptor subfamily 2 group C member 1" P13056 12 95020229-95073628 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035040, HPA035041, HPA067767" Supported Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Cell Junctions, Cytosol" "HPA035040: AB_2674426, HPA035041: AB_2674427, HPA067767: AB_2685898" "unprognostic (2.44e-1)" "unprognostic (8.04e-3)" "unprognostic (3.17e-2)" "unprognostic (2.51e-1)" "unprognostic (3.56e-3)" "unprognostic (3.01e-2)" "prognostic unfavorable (5.18e-5)" "unprognostic (1.30e-2)" "unprognostic (1.29e-2)" "unprognostic (1.86e-1)" "unprognostic (3.83e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (2.31e-1)" "unprognostic (1.42e-1)" "unprognostic (2.16e-1)" "prognostic favorable (5.62e-5)" 8.3 10.4 4.9 5.0 5.6 9.3 7.7 14.0 9.3 9.3 8.2 8.6 5.6 10.3 9.9 5.4 10.2 4.4 10.0 5.1 5.1 6.6 10.0 8.6 5.5 4.7 4.9 9.9 8.2 6.1 7.2 5.8 5.6 6.7 6.2 15.6 5.2 7.5 14.3 6.1 7.6 7.8 4.6 9.2 6.1 11.9 5.6 5.7 11.9 5.5 5.3 8.1 7.4 6.9 11.4 13.9 23.0 10.2 5.8 10.0 30.5 10.9 7.9 10.6 9.9 12.2 6.2 13.8 3.8 7.3 6.8 11.8 10.7 8.6 8.1 6.0 23.1 16.7 11.5 15.4 11.1 11.3 7.0 10.2 7.0 7.9 9.5 13.3 11.6 16.8 12.9 5.2 12.9 8.3 12.4 26.0 14.5 9.1 24.0 11.7 15.0 8.1 12.3 13.9 11.1 8.8 17.6 7.4 8.4 11.8 12.9 7.5 10.9 8.6 8.4 10.7 6.2 7.7 13.1 13.0 2.1 13.0 4.2 0.3 2.4 2.1 3.9 2.6 5.0 2.0 3.1 3.3 3.7 2.3 4.0 2.8 1.5 2.1 2.3 3.6 2.3 2.3 4.9 5.6 14.0 9.3 5.1 5.1 4.7 4.9 5.6 4.6 5.6 6.9 18.7 35.3 15.4 28.4 14.4 8.3 14.4 7.8 15.4 44.8 7.6 7.5 18.5 8.6 5.6 11.0 18.8 15.3 19.9 10.3 3.9 11.6 25.2 14.8 23.3 15.5 7.2 15.6 55.4 9.4 12.7 17.4 16.3 18.8 10.1 28.0 13.2 12.7 9.5 25.2 73.4 11.4 12.2 11.1 9.5 6.4 43.8 10.9 14.2 34.7 10.7 14.9 12.3 26.2 51.1 18.7 9.9 30.1 13.7 9.4 5.8 8.1 19.6 49.6 6.6 17.3 14.6 67.0 25.9 12.1 7.4 7.8 15.0 18.0 13.3 20.2 NR3C1 "GR, GRL" ENSG00000113580 "Nuclear receptor subfamily 3 group C member 1" P04150 5 143277931-143435512 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Receptor, RNA-binding" "Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 411.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004248, CAB010435" Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" Mitochondria "CAB010435: AB_2155784, HPA004248: AB_1078976" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.43e-2)" "unprognostic (2.74e-1)" "unprognostic (4.19e-1)" "unprognostic (1.39e-1)" "unprognostic (2.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.15e-1)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.72e-6)" "unprognostic (9.06e-3)" "unprognostic (1.02e-1)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" 35.3 11.8 15.2 22.6 18.1 49.4 25.5 34.0 24.7 19.7 18.2 13.7 19.2 18.8 13.6 25.7 18.8 21.1 24.2 14.9 25.0 19.2 39.8 31.9 25.6 18.1 14.9 21.1 14.7 33.8 16.2 46.9 16.1 19.7 14.5 9.5 16.1 20.0 45.0 20.4 18.0 23.8 15.0 24.5 16.0 11.1 21.6 40.0 25.6 40.1 27.3 18.2 16.0 28.5 30.4 60.6 4.4 0.1 38.2 42.3 5.2 46.5 55.3 39.3 45.1 4.5 39.7 26.8 20.8 68.6 46.0 28.1 0.3 36.6 48.3 15.2 21.0 6.9 77.0 13.5 35.7 28.1 20.6 30.8 46.3 64.7 62.5 49.0 15.0 12.1 10.3 98.8 35.1 10.9 16.7 20.0 11.9 5.1 13.0 6.0 41.4 58.0 11.5 2.1 8.0 6.1 81.3 11.7 19.4 4.9 5.3 39.8 35.8 94.7 18.7 45.7 35.9 20.1 19.7 41.5 49.7 28.5 33.6 67.4 21.3 38.9 18.3 24.2 15.1 15.9 18.6 17.9 28.5 22.3 17.8 17.2 68.4 23.1 23.6 25.9 12.8 17.3 15.2 18.1 34.0 24.7 14.9 25.0 18.1 14.9 16.1 15.0 21.6 28.5 152.3 67.3 69.1 71.2 134.1 58.8 35.9 37.9 79.6 13.1 39.0 55.8 43.4 57.2 41.2 25.8 16.7 48.9 158.3 22.9 17.6 30.8 165.6 8.1 30.1 82.3 28.1 55.9 411.4 33.3 39.5 112.2 23.9 10.4 89.3 7.5 63.5 193.9 53.2 37.0 169.5 4.1 10.2 66.3 99.2 144.1 63.0 97.4 53.4 241.7 87.6 34.6 83.4 240.3 237.5 35.9 17.9 71.5 115.1 46.2 25.3 67.9 37.9 65.0 151.2 181.9 105.0 24.5 40.1 57.4 56.3 36.5 204.5 12.6 12.9 14.3 NRBP1 "BCON3, MADM, MUDPNP, NRBP" ENSG00000115216 "Nuclear receptor binding protein 1" Q9UHY1 2 27427790-27442259 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 234.3;Extravillous trophoblasts: 231.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029527, CAB033078" Supported Supported Cytosol NA NA 39000 "Cluster 2: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "CAB033078: AB_2154375, HPA029527: AB_10601379" "unprognostic (4.95e-3)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" "unprognostic (1.38e-1)" "unprognostic (3.62e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.22e-5)" "unprognostic (7.36e-2)" "unprognostic (1.44e-1)" "unprognostic (6.11e-2)" "unprognostic (3.13e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.84e-5)" "unprognostic (1.26e-1)" "unprognostic (2.69e-1)" "unprognostic (2.75e-2)" "unprognostic (3.48e-3)" 59.7 49.6 38.1 49.4 38.9 109.1 55.2 39.3 42.1 76.1 44.3 72.0 52.2 69.7 43.1 99.9 55.1 53.5 57.6 37.7 44.5 44.7 55.2 50.3 54.0 43.1 44.2 63.7 51.0 44.5 46.9 83.0 45.6 51.6 46.5 47.6 57.2 60.7 126.2 70.7 52.4 75.6 36.8 51.2 51.8 71.1 42.1 51.9 42.4 90.3 67.2 67.3 70.8 37.5 123.7 121.0 98.1 130.9 148.2 146.6 119.0 114.8 143.1 159.8 123.5 123.5 49.1 35.5 83.7 182.9 158.6 82.9 98.4 102.9 102.3 70.0 61.4 70.8 47.0 163.5 124.1 40.0 91.1 120.8 127.3 163.7 108.6 103.9 178.5 38.8 40.5 54.8 142.3 185.6 53.0 96.1 124.0 108.5 75.7 40.5 209.5 40.0 113.8 84.1 26.3 74.1 135.6 96.5 72.4 108.8 53.3 43.9 143.0 140.6 138.5 85.1 94.2 114.3 122.7 42.4 109.8 68.6 71.9 203.6 88.6 187.0 96.7 118.0 85.6 59.3 82.3 87.9 90.2 55.1 73.9 77.1 117.9 91.0 111.5 57.4 107.8 117.4 38.1 38.9 39.3 42.1 37.7 44.5 43.1 44.2 45.6 36.8 42.1 37.5 47.3 6.4 21.4 15.7 46.4 57.2 57.8 73.9 56.9 37.8 34.3 31.5 25.9 28.6 47.2 35.0 35.5 155.7 72.6 67.4 31.3 88.7 234.3 47.5 66.8 54.9 28.1 42.7 14.8 95.9 231.5 61.8 30.1 64.1 20.8 39.3 47.2 38.8 77.3 28.6 15.9 42.7 38.7 35.2 44.7 38.6 46.0 46.6 30.2 8.4 67.2 46.8 51.5 13.0 17.0 100.0 45.6 60.5 72.2 49.7 67.4 52.6 36.5 56.3 32.9 37.4 77.6 92.8 106.8 50.3 52.4 203.2 67.2 36.9 30.8 58.8 NRCAM "Bravo, KIAA0343" ENSG00000091129 "Neuronal cell adhesion molecule" Q92823 7 108147623-108456717 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 37.3;brain: 38.3;epididymis: 34.4;retina: 38.0" "Group enriched" "Detected in many" 7 "Astrocytes: 612.5;Excitatory neurons: 764.5;Inhibitory neurons: 392.4;Oligodendrocyte precursor cells: 1259.2" "Cancer enriched" "Detected in all" 7 "glioma: 57.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive CD8 T-cell: 2.0" "Lineage enriched" "Detected in single" 15 "T-cells: 2.0" "Cell line enhanced" "Detected in many" "A549: 99.6;AF22: 94.8;EFO-21: 175.4;HMC-1: 187.9;SH-SY5Y: 115.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012606 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in brain" NA NA 110000000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Plasma membrane" "HPA012606: AB_1854636" "unprognostic (2.66e-1)" "unprognostic (2.65e-1)" "unprognostic (2.52e-3)" "unprognostic (2.18e-2)" "unprognostic (4.08e-3)" "unprognostic (1.01e-2)" "unprognostic (4.47e-3)" "unprognostic (1.66e-1)" "unprognostic (1.73e-1)" "unprognostic (4.81e-2)" "unprognostic (9.10e-3)" "unprognostic (4.33e-2)" "unprognostic (2.22e-2)" "unprognostic (9.70e-3)" "unprognostic (6.42e-2)" "unprognostic (6.51e-3)" "unprognostic (3.28e-2)" 3.1 37.3 19.8 1.8 31.9 0.3 1.5 2.4 34.6 5.0 0.0 0.8 0.7 2.1 34.4 0.7 3.6 7.3 0.4 33.1 9.4 6.2 0.4 2.3 0.8 2.3 22.7 1.5 29.4 7.3 11.4 7.8 2.0 0.8 0.7 38.0 1.9 14.2 0.2 0.8 0.6 0.7 1.5 4.8 1.8 1.7 38.3 2.8 4.1 0.4 2.7 0.5 0.4 2.6 0.1 99.6 94.8 0.0 11.4 2.2 1.8 0.7 0.4 1.0 1.7 40.7 0.0 0.0 175.4 0.7 1.5 0.4 2.2 1.6 1.0 0.1 12.7 0.0 0.7 1.0 0.2 0.9 187.9 15.5 0.0 0.2 0.6 0.2 61.7 0.2 0.2 0.8 1.5 38.2 0.4 0.3 13.1 60.1 0.0 0.0 27.8 33.3 21.4 0.1 18.6 115.9 1.3 0.0 1.9 3.3 0.2 0.1 66.2 4.2 1.0 0.1 16.4 0.2 0.5 0.9 0.7 0.1 55.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.2 19.8 31.9 2.4 34.6 33.1 9.4 2.3 22.7 2.0 1.5 38.3 2.6 0.2 0.0 0.0 612.5 0.8 0.4 0.1 0.8 1.2 66.2 1.5 0.9 0.7 7.2 0.1 5.5 102.2 3.6 0.0 0.2 3.9 1.6 37.3 10.4 2.4 1.3 0.0 0.0 764.5 12.1 0.2 2.0 3.6 25.0 23.4 4.4 1.4 0.4 0.8 13.5 392.4 0.3 0.0 0.8 0.4 8.3 0.9 0.2 3.6 51.5 0.6 45.1 0.0 1259.2 21.9 3.7 0.0 0.4 2.6 1.2 0.0 3.3 0.1 8.8 0.0 1.0 2.6 1.1 2.7 0.2 0.1 4.4 1.1 34.2 0.0 0.0 NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Group enriched" "Detected in many" 17 "Excitatory neurons: 1466.4;Inhibitory neurons: 411.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 55.3" "Lineage enriched" "Detected in many" 5 "monocytes: 55.3" "Cell line enhanced" "Detected in many" "A549: 132.5;BJ: 91.3;fHDF/TERT166: 98.1;GAMG: 95.4;U-2197: 84.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA010964: AB_1854641" "unprognostic (5.76e-3)" "unprognostic (8.60e-2)" "unprognostic (1.96e-4)" "unprognostic (2.67e-1)" "unprognostic (1.94e-4)" "unprognostic (4.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" "unprognostic (5.65e-2)" "unprognostic (7.99e-2)" "unprognostic (8.49e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (5.40e-2)" "unprognostic (7.83e-2)" 0.5 1.2 3.5 6.1 3.2 1.4 5.7 8.7 13.2 8.0 3.2 3.2 2.9 1.2 0.6 2.8 1.1 2.3 1.9 0.4 12.7 8.6 17.0 3.7 0.4 35.4 8.0 1.9 0.7 0.6 3.8 0.2 35.3 2.6 3.2 11.6 2.6 1.0 0.1 4.9 2.5 1.0 2.7 1.6 2.5 5.3 2.6 0.8 9.9 0.0 2.1 9.4 3.4 8.2 0.4 132.5 1.8 0.0 0.9 2.5 0.2 91.3 60.0 65.3 55.8 0.0 2.9 0.0 16.4 98.1 95.4 76.7 0.3 34.5 69.4 0.2 0.7 1.3 1.8 2.0 0.4 0.1 0.2 1.3 3.4 81.1 74.6 5.7 41.2 0.1 0.0 0.7 24.4 0.1 0.0 0.1 2.5 0.0 0.0 0.1 0.9 0.0 52.9 3.6 3.4 4.0 7.5 0.0 0.1 5.0 0.0 0.3 34.7 50.7 15.8 84.4 53.6 0.1 0.0 0.9 28.2 0.1 6.6 0.2 55.3 0.9 0.2 4.7 0.2 0.1 0.1 0.0 12.1 0.1 0.0 0.0 2.0 0.2 0.2 0.2 0.0 14.2 3.5 3.2 8.7 13.2 0.4 12.7 35.4 8.0 35.3 2.7 2.6 8.2 0.1 38.5 2.7 29.7 0.8 26.0 48.0 5.1 21.1 11.0 4.3 18.2 2.0 8.6 7.9 3.7 8.4 0.0 1.3 0.0 9.8 1.8 41.5 0.1 1.9 5.7 0.0 0.0 1466.4 0.2 0.0 10.5 0.0 0.2 1.3 3.2 7.1 5.3 0.5 28.6 411.8 0.0 2.0 10.2 1.9 23.5 0.3 22.1 1.8 36.5 49.2 5.0 0.0 54.3 19.2 0.9 0.0 0.4 0.0 42.9 0.0 18.7 2.4 3.1 0.0 0.1 9.3 11.3 5.0 3.2 6.1 0.0 0.6 0.0 0.0 6.5 NRN1L "MRCC2446, UNQ2446" ENSG00000188038 "Neuritin 1 like" Q496H8 16 67884885-67888855 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 12.0;Astrocytes: 2.9;Bipolar cells: 2.0;Oligodendrocytes: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 5 "BEWO: 38.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041761 Uncertain "Secreted - unknown location" NA NA "Cluster 37: B-cells - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "HPA041761: AB_10961155" "unprognostic (2.79e-2)" "unprognostic (3.32e-1)" "unprognostic (1.19e-1)" "unprognostic (3.99e-2)" "unprognostic (4.85e-1)" 1.8 1.4 5.0 0.9 6.6 3.7 1.7 7.2 8.2 2.6 9.6 1.3 1.0 1.3 0.4 1.1 2.9 0.7 2.5 4.8 6.0 1.8 2.4 1.9 2.1 5.6 4.9 4.7 1.3 0.7 6.2 0.6 5.6 2.7 0.5 5.5 1.7 0.8 2.1 3.2 1.7 0.5 4.4 2.5 1.2 1.8 5.4 1.1 2.5 0.7 0.6 2.0 2.1 6.6 0.1 0.5 0.7 0.9 0.3 1.1 38.1 0.4 0.1 0.4 0.3 0.0 0.6 0.5 0.7 0.1 0.0 0.4 0.1 0.3 0.3 0.3 0.9 0.4 1.5 2.0 0.6 0.2 1.4 0.5 1.2 0.1 0.0 0.4 0.1 1.4 0.9 0.7 0.1 1.6 0.5 4.3 7.1 0.0 0.5 1.5 0.0 0.7 0.3 0.4 1.1 0.4 0.5 0.5 0.5 6.8 1.0 1.4 0.6 0.3 0.3 0.0 0.1 0.1 0.4 0.9 0.1 0.4 0.2 0.0 0.5 0.0 1.0 0.3 0.6 0.5 0.6 0.3 0.1 0.2 0.5 0.3 0.6 0.3 0.4 0.1 0.4 0.3 5.0 6.6 7.2 8.2 4.8 6.0 5.6 4.9 5.6 4.4 5.4 6.6 0.1 3.2 12.0 2.9 0.1 0.3 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.9 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.1 NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 366.0;Endothelial cells: 174.4;Hepatic stellate cells: 184.6;Sertoli cells: 282.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 48.6" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.3" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 444.6;hTERT-RPE1: 371.6;TIME: 369.5;U-87 MG: 425.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved "Secreted in other tissues" NA NA 780000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004511: AB_2282634, HPA030278: AB_10601976" "unprognostic (3.19e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (1.50e-2)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (6.17e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.87e-4)" "prognostic unfavorable (1.22e-5)" "unprognostic (3.83e-2)" "unprognostic (5.48e-2)" "unprognostic (7.79e-2)" 125.2 42.3 9.3 43.3 9.4 3.7 62.2 0.0 26.0 36.9 13.3 26.6 21.3 51.6 35.7 19.7 34.5 54.1 80.8 48.6 9.1 52.7 53.1 63.7 23.7 4.0 3.9 43.0 33.0 24.4 9.0 133.7 2.1 21.3 23.6 11.6 19.3 38.4 55.9 22.1 21.0 55.9 5.7 66.7 18.6 12.9 13.4 18.2 49.7 46.6 12.4 35.3 20.0 10.7 57.4 217.8 11.1 1.1 204.8 224.7 1.3 224.4 216.2 109.6 118.2 28.9 132.4 1.1 26.6 444.6 116.8 15.8 13.8 65.2 89.3 0.7 11.2 0.6 24.5 48.7 74.3 20.8 1.6 277.3 11.2 261.7 116.8 371.6 304.0 1.4 0.7 1.4 221.3 96.8 1.4 3.9 5.5 11.9 204.2 9.6 24.8 1.2 109.7 1.3 5.1 2.7 23.0 17.5 0.9 9.2 1.0 3.3 369.5 156.4 36.9 193.0 153.8 0.7 1.1 0.7 425.2 26.4 143.5 0.4 2.5 0.5 0.6 0.4 1.0 0.7 0.7 0.6 2.3 0.6 0.6 0.6 0.4 1.2 0.3 39.3 0.6 0.9 9.3 9.4 0.0 26.0 48.6 9.1 4.0 3.9 2.1 5.7 13.4 10.7 366.0 0.0 20.2 80.3 4.3 15.7 10.6 5.5 7.4 10.5 4.2 5.5 67.6 28.6 13.0 18.4 4.2 61.5 29.4 0.6 1.9 57.9 1.3 11.3 116.9 174.4 4.2 3.2 105.4 18.9 13.4 58.5 6.6 11.0 7.6 62.3 184.6 12.5 135.4 0.0 14.4 1.8 16.2 62.7 33.3 5.5 42.3 46.0 12.4 78.7 5.8 3.4 0.0 11.6 2.3 15.4 0.0 21.1 1.6 4.1 3.0 59.8 5.4 0.9 282.7 13.1 117.9 0.2 1.3 2.7 10.5 67.2 3.8 61.1 1.5 3.3 NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 78.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 134.4;Hepatic stellate cells: 137.8;Hofbauer cells: 141.3;Langerhans cells: 129.8;monocytes: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 123.6;HUVEC TERT2: 105.7;TIME: 106.3;U-251 MG: 217.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" NA NA 29000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" 18.8 22.2 18.0 17.8 13.8 4.6 12.6 9.3 11.7 18.8 7.0 78.7 5.3 51.8 3.7 13.3 21.1 31.1 6.3 21.7 42.5 4.9 9.6 24.3 8.2 30.4 23.9 46.8 1.9 2.5 9.6 47.0 19.6 13.0 10.5 3.6 3.3 30.9 2.3 4.8 14.9 54.8 13.2 7.5 25.9 1.4 33.9 6.1 10.8 3.4 4.5 38.3 15.9 12.4 2.5 50.4 32.2 0.2 30.1 9.6 9.3 8.5 14.8 10.0 9.5 48.0 123.6 0.0 11.9 25.3 20.5 19.2 1.5 15.9 16.8 0.1 6.8 0.5 2.4 0.4 80.7 0.0 2.1 68.5 12.2 14.4 12.3 64.5 105.7 0.2 0.2 0.1 6.8 0.2 0.0 0.0 41.5 0.1 9.2 0.2 2.0 12.0 21.7 0.0 29.0 1.0 1.1 0.3 75.4 84.9 0.1 0.8 106.3 43.1 0.4 11.3 217.0 0.0 0.2 3.2 96.9 0.3 88.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.0 13.8 9.3 11.7 21.7 42.5 30.4 23.9 19.6 13.2 33.9 12.4 88.7 89.8 57.5 2.0 3.8 19.4 19.5 30.8 97.9 36.5 1.3 11.3 4.5 5.7 53.2 1.8 0.0 89.7 0.1 0.6 0.0 6.4 6.3 8.8 8.1 134.4 1.2 2.7 4.1 3.8 8.7 47.0 1.5 13.2 3.8 2.7 137.8 1.8 141.3 0.0 9.4 1.1 4.1 28.0 129.8 18.9 2.8 53.7 19.6 53.4 224.8 4.8 0.0 4.0 8.1 53.2 0.0 4.9 0.2 9.1 0.0 0.6 48.1 2.7 0.0 4.6 32.2 1.4 1.4 17.8 12.6 25.7 2.4 48.1 0.4 51.5 NRTN NTN ENSG00000171119 Neurturin Q99748 19 5823802-5828324 "Disease related genes, Predicted secreted proteins" "Growth factor" "Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 25.6;pancreas: 16.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.2;Cone photoreceptor cells: 12.5;Endometrial ciliated cells: 14.9;Hepatocytes: 12.3;Rod photoreceptor cells: 50.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 8.2;K-562: 8.1;REH: 21.0;SH-SY5Y: 10.8;U-266/70: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA065260 Approved "Golgi apparatus" "Secreted to blood" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 14: REH - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA065260: AB_2685448" "unprognostic (4.85e-2)" "unprognostic (1.66e-2)" "unprognostic (2.96e-2)" "prognostic favorable (3.86e-4)" "unprognostic (1.60e-2)" "prognostic favorable (7.23e-4)" "unprognostic (8.21e-3)" "unprognostic (5.60e-3)" "prognostic favorable (9.92e-4)" "unprognostic (1.38e-1)" "unprognostic (2.08e-2)" "unprognostic (1.28e-2)" "unprognostic (6.78e-3)" "unprognostic (3.39e-1)" "unprognostic (1.65e-1)" "unprognostic (1.22e-1)" "unprognostic (4.32e-2)" 0.3 8.2 0.1 0.4 0.2 0.0 0.8 0.4 0.5 1.5 0.4 9.6 1.2 0.4 0.6 4.4 1.1 0.5 25.6 0.2 0.2 2.8 14.4 0.8 0.0 0.5 0.5 0.1 16.9 1.5 1.1 0.2 0.6 2.8 0.2 9.7 5.3 0.9 0.0 6.1 3.1 0.9 0.1 0.2 9.4 1.3 0.4 0.4 0.4 0.0 0.2 4.6 3.0 0.4 0.6 0.8 0.9 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.9 0.0 0.5 0.1 3.2 0.0 0.0 8.2 5.7 0.0 0.0 2.6 0.9 0.1 2.1 0.1 0.8 0.0 0.0 0.0 0.0 2.7 8.1 0.0 0.0 1.7 0.7 0.9 2.6 1.2 2.0 21.0 2.6 4.9 0.3 0.0 0.5 10.8 0.2 1.0 1.2 0.3 0.4 0.7 0.0 0.0 1.6 0.0 0.0 11.5 2.6 0.7 0.0 1.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.2 0.4 0.5 0.2 0.2 0.5 0.5 0.6 0.1 0.4 0.4 0.3 0.0 1.8 0.3 0.4 1.9 1.4 0.4 1.8 4.6 3.0 6.9 17.2 1.5 0.1 3.7 12.5 0.1 0.4 1.0 3.9 0.3 0.1 14.9 4.3 0.6 1.2 0.0 0.5 0.7 0.0 1.3 2.0 2.6 0.0 1.1 3.6 12.3 0.3 0.0 0.7 1.8 0.0 0.3 0.2 0.6 0.9 0.3 5.4 0.0 0.1 6.0 1.0 0.5 1.0 0.7 0.1 0.0 2.5 1.0 0.2 0.7 0.2 50.0 0.0 0.0 0.9 0.4 3.4 1.4 4.5 0.1 0.6 0.5 1.4 1.1 NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Mental retardation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 145.0" "Group enriched" "Detected in many" 5 "Astrocytes: 4025.1;Excitatory neurons: 3206.3;Inhibitory neurons: 2116.2;Oligodendrocyte precursor cells: 4897.8" "Cancer enriched" "Detected in single" 8 "glioma: 3.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Supported "Plasma membrane" "Intracellular and membrane" NA NA 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA071400: AB_2732180" "unprognostic (7.01e-2)" "unprognostic (9.96e-2)" "unprognostic (7.68e-2)" "unprognostic (1.74e-4)" "unprognostic (2.46e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (6.37e-4)" "unprognostic (2.85e-2)" "unprognostic (6.68e-7)" "unprognostic (3.40e-2)" "unprognostic (1.75e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-3)" 1.1 2.0 40.9 1.1 60.9 0.3 0.8 145.0 74.4 2.2 0.0 11.3 0.9 1.1 3.0 2.0 0.8 1.2 5.2 62.7 16.8 0.4 0.5 0.4 0.3 0.0 2.2 0.9 1.4 0.0 6.0 0.0 7.2 2.8 2.6 7.2 2.4 8.4 0.2 0.9 2.6 1.0 4.7 0.2 2.3 5.6 15.7 1.2 0.6 0.8 0.2 2.3 3.1 22.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 31.3 1.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 3.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 40.9 60.9 145.0 74.4 62.7 16.8 0.0 2.2 7.2 4.7 15.7 22.0 0.1 0.0 0.0 4025.1 0.0 0.0 0.3 0.0 3.4 116.0 3.1 3.7 19.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.1 201.6 0.1 2.8 1.0 1.8 0.0 3206.3 0.0 0.0 2.3 0.0 0.1 0.0 0.2 3.3 0.2 0.1 77.4 2116.2 0.0 0.0 0.0 0.6 103.4 2.5 0.6 1.8 174.3 0.0 22.7 0.0 4897.8 678.0 0.2 0.0 0.7 1.4 0.5 0.0 0.2 0.0 9.7 0.0 2.5 1.3 13.3 5.8 0.6 0.1 0.3 0.1 0.1 0.0 0.1 NRXN2 ENSG00000110076 "Neurexin 2" "P58401, Q9P2S2" 11 64606174-64723197 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.4;Horizontal cells: 149.7;Inhibitory neurons: 47.8;Late spermatids: 49.7;Muller glia cells: 60.7;Oligodendrocyte precursor cells: 47.3;Peritubular cells: 59.0" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 47.8;SCLC-21H: 22.8;SH-SY5Y: 10.5;U-2 OS: 26.1;U-87 MG: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 1000000 "Cluster 7: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 14: REH - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (3.87e-2)" "unprognostic (1.54e-4)" "unprognostic (2.60e-2)" "unprognostic (1.96e-1)" "unprognostic (8.07e-2)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (5.08e-2)" "unprognostic (3.23e-1)" "unprognostic (5.93e-3)" "unprognostic (3.40e-1)" "unprognostic (9.97e-3)" "unprognostic (2.39e-2)" "unprognostic (6.99e-2)" "unprognostic (4.27e-4)" "unprognostic (5.46e-3)" 3.8 4.7 61.0 2.0 51.6 0.5 2.6 73.6 65.9 27.0 0.0 17.1 1.0 19.0 1.1 0.4 14.6 2.2 3.7 61.9 21.8 5.8 1.0 1.5 1.0 16.0 18.2 15.5 3.0 0.1 4.3 0.7 11.6 4.9 0.6 13.0 1.6 2.9 1.1 0.9 2.7 2.4 4.6 1.5 2.4 15.3 24.8 0.8 4.0 0.3 0.4 5.9 7.4 18.3 0.0 0.0 2.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 2.1 0.0 0.3 0.3 2.5 2.0 0.1 3.3 0.0 0.0 0.3 0.4 6.5 0.0 0.0 0.0 0.0 0.5 1.2 0.0 4.5 0.0 0.0 0.0 0.1 0.0 9.0 3.1 0.0 0.7 0.3 7.6 0.0 0.0 47.8 1.4 1.9 0.0 0.0 22.8 10.5 0.1 0.0 0.0 0.1 0.0 0.0 0.3 1.1 26.1 0.5 0.0 0.0 0.0 0.0 18.6 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 61.0 51.6 73.6 65.9 61.9 21.8 16.0 18.2 11.6 4.6 24.8 18.3 0.5 0.0 0.0 13.1 0.0 0.5 0.1 0.0 0.0 72.4 0.2 0.6 3.2 0.0 0.0 1.8 6.2 0.1 0.6 6.3 3.9 0.0 23.6 0.9 23.5 2.5 6.7 2.1 36.0 2.7 0.2 7.3 0.0 0.6 0.0 0.7 2.9 8.6 0.2 149.7 47.8 1.1 0.0 1.2 0.7 49.7 42.6 1.2 0.0 7.5 0.7 60.7 6.2 47.3 26.0 0.4 2.5 59.0 0.0 0.1 5.1 40.9 0.0 21.7 0.0 27.3 4.0 37.5 15.2 0.0 0.1 0.3 0.7 4.9 0.9 0.0 NRXN3 "C14orf60, KIAA0743" ENSG00000021645 "Neurexin 3" "Q9HDB5, Q9Y4C0" 14 78170373-79868291 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.8;retina: 42.9" "Group enriched" "Detected in many" 10 "Excitatory neurons: 3526.5;Inhibitory neurons: 5083.8;Oligodendrocytes: 2145.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 106.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 9.7;RT4: 24.7;SK-BR-3: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002727 Approved NA NA 710000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA002727: AB_1079468" "unprognostic (7.96e-2)" "unprognostic (5.70e-4)" "unprognostic (8.18e-3)" "unprognostic (2.19e-2)" "unprognostic (2.31e-4)" "unprognostic (9.56e-2)" "unprognostic (2.80e-1)" "unprognostic (2.99e-3)" "unprognostic (1.12e-2)" "unprognostic (7.91e-2)" "unprognostic (2.40e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.83e-7)" "unprognostic (4.81e-2)" "unprognostic (2.61e-1)" "unprognostic (3.61e-2)" "unprognostic (2.91e-1)" 0.8 5.9 13.4 2.8 17.0 0.1 1.6 106.8 48.3 3.9 0.0 23.0 2.3 5.4 1.7 4.7 5.0 2.5 3.0 23.6 21.3 1.7 0.4 2.6 0.4 8.6 24.2 0.7 3.1 8.8 4.9 1.3 7.2 6.7 4.1 42.9 2.8 11.3 0.3 1.8 8.4 21.1 0.0 5.8 9.3 7.5 4.2 1.0 0.5 0.5 0.4 4.4 2.7 21.5 0.0 0.0 7.6 0.0 0.2 0.3 0.0 3.0 2.2 9.7 7.3 2.6 0.0 0.1 0.0 0.3 0.0 2.8 0.1 0.3 6.8 3.0 6.0 0.0 0.2 0.0 0.7 0.0 0.0 1.8 0.3 4.3 1.4 4.6 2.5 0.0 0.0 0.2 0.1 0.1 0.2 0.2 1.6 0.0 0.0 0.2 0.0 0.0 5.2 24.7 1.3 0.0 0.0 9.3 0.5 3.1 0.0 0.0 0.0 0.1 6.2 0.0 3.2 0.0 0.0 0.0 1.8 0.3 5.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.4 17.0 106.8 48.3 23.6 21.3 8.6 24.2 7.2 0.0 4.2 21.5 0.2 12.8 5.5 100.2 0.0 4.6 7.0 0.4 0.6 180.7 3.2 3.0 3.9 1.5 3.4 3.7 12.5 9.2 0.0 1.1 0.0 2.2 15.9 36.3 2.2 0.8 6.0 0.0 3526.5 3.1 0.5 1.8 0.0 31.5 0.0 0.8 1.4 0.1 0.7 116.1 5083.8 0.6 4.1 0.0 0.3 18.9 7.5 0.3 17.8 88.1 0.0 54.3 0.0 328.2 2145.0 0.7 0.2 6.4 1.2 7.5 0.0 0.1 9.3 10.7 0.0 0.4 2.2 2.1 0.8 0.1 0.9 37.9 0.6 0.0 1.0 3.0 NT5C3A "cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1" ENSG00000122643 "5'-nucleotidase, cytosolic IIIA" Q9H0P0 7 33014114-33062797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 87.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 191.0;Paneth cells: 186.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010520, HPA010630, HPA029058" Uncertain Supported "Nucleoplasm,Nuclear bodies,Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 10000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Endoplasmic reticulum, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA010520: , HPA010630: AB_2668319, HPA029058: AB_10601380" "unprognostic (7.50e-2)" "unprognostic (3.10e-1)" "unprognostic (1.14e-1)" "unprognostic (2.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (3.25e-2)" "unprognostic (3.12e-2)" "unprognostic (2.82e-3)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (9.37e-2)" "unprognostic (2.05e-1)" "unprognostic (2.12e-3)" "unprognostic (3.43e-3)" 12.4 14.3 11.4 26.1 11.4 32.6 21.3 15.2 15.6 12.6 10.8 51.9 40.0 16.9 14.3 18.6 15.9 23.4 16.6 11.5 11.5 22.4 11.8 17.6 30.8 11.1 11.8 13.4 21.4 9.7 7.5 16.3 11.5 12.3 51.0 20.4 9.7 10.0 87.4 28.7 37.3 13.2 12.7 22.9 27.0 9.5 12.0 22.5 17.1 51.0 45.8 23.8 14.4 13.1 42.2 27.6 25.2 29.6 21.2 16.1 20.3 44.8 30.5 29.2 38.9 19.9 115.1 100.4 27.7 29.6 48.3 63.8 28.3 30.8 40.4 16.2 36.2 54.7 36.5 28.7 23.3 55.6 36.9 21.7 23.8 35.9 63.0 16.4 22.2 33.2 43.3 24.8 37.3 29.9 25.0 87.8 27.8 47.1 31.2 25.9 22.9 60.0 87.8 39.8 28.1 37.0 31.1 52.4 66.6 24.5 35.2 33.5 19.8 25.1 20.9 42.6 55.7 50.6 69.0 54.8 20.6 34.9 42.5 112.5 25.9 82.5 26.6 32.7 30.6 64.0 34.2 30.8 22.1 63.6 34.5 29.1 103.8 28.2 39.2 20.6 56.2 37.9 11.4 11.4 15.2 15.6 11.5 11.5 11.1 11.8 11.5 12.7 12.0 13.1 39.1 22.4 13.7 30.7 85.1 46.8 40.9 85.3 47.8 23.9 22.6 18.9 16.9 32.9 40.4 16.5 41.7 36.9 42.5 191.0 29.4 34.4 5.7 40.9 21.0 40.8 119.6 127.1 45.3 79.0 31.6 35.2 42.8 21.4 17.7 38.3 30.0 18.9 25.0 1.7 49.4 98.9 40.7 31.2 23.5 5.0 33.8 111.4 26.6 29.0 37.0 23.4 55.6 48.2 52.4 48.3 186.6 22.2 43.8 45.7 91.8 84.8 53.7 27.1 13.1 30.7 24.9 46.4 24.0 35.5 38.9 28.3 53.7 23.3 71.0 65.9 NT5DC3 "FLJ11266, TU12B1-TY" ENSG00000111696 "5'-nucleotidase domain containing 3" Q86UY8 12 103770453-103841234 "Metabolic proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 80.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 41.2;Excitatory neurons: 36.6;Oligodendrocyte precursor cells: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-HME1: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041634 Approved Mitochondria,Cytosol "Secreted - unknown location" NA NA "Cluster 30: Non-specific - Translation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Mitochondria Cytosol "HPA041634: AB_10795597" "unprognostic (2.61e-2)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (2.72e-1)" "unprognostic (8.45e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.57e-1)" "unprognostic (2.19e-1)" "unprognostic (2.45e-2)" "unprognostic (5.43e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.60e-3)" "unprognostic (7.42e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (8.11e-4)" 2.9 4.0 14.2 1.9 12.0 17.5 3.3 0.0 13.3 9.3 0.0 80.5 1.0 23.1 5.0 5.2 3.7 1.4 1.9 23.3 7.8 2.0 5.0 2.8 1.3 1.5 1.8 2.9 3.5 0.8 4.5 1.5 1.4 7.5 7.7 2.3 4.1 5.4 7.8 2.5 4.7 6.8 1.2 1.6 6.6 3.1 8.9 0.6 1.9 3.3 1.2 21.7 5.7 4.8 3.6 6.5 3.6 4.2 5.1 4.0 6.8 5.9 3.5 4.1 2.6 4.4 0.9 6.1 1.1 7.0 4.5 4.1 5.2 11.7 5.9 4.5 4.2 7.6 2.5 5.2 2.8 4.1 1.9 3.5 2.5 5.3 22.7 8.3 2.4 3.0 12.2 3.0 9.2 3.3 3.6 6.6 4.5 5.2 6.9 4.9 6.3 2.3 6.5 2.4 4.9 2.0 4.9 5.4 7.1 3.3 3.1 3.8 3.2 4.0 4.8 5.5 11.9 2.7 3.5 4.4 3.8 6.2 6.0 0.4 0.5 0.0 0.6 0.6 1.2 1.3 0.9 0.5 1.5 1.4 0.7 0.6 0.9 0.6 0.4 1.9 0.2 0.3 14.2 12.0 0.0 13.3 23.3 7.8 1.5 1.8 1.4 1.2 8.9 4.8 1.4 0.0 2.3 3.9 2.7 4.5 21.9 3.0 21.6 2.0 5.6 7.4 3.8 2.8 2.1 1.8 0.0 5.2 2.7 5.8 0.0 2.1 12.1 14.0 11.9 1.7 41.2 1.3 36.6 2.0 4.7 3.8 7.7 19.4 0.0 3.7 0.7 5.3 1.8 10.1 24.4 11.4 10.2 4.1 6.5 10.5 5.0 2.8 0.0 6.5 2.9 0.8 1.0 29.1 2.7 2.7 2.2 8.2 2.7 13.0 1.1 2.1 6.9 5.0 0.0 5.6 5.7 0.4 3.1 9.0 4.4 4.1 2.5 4.1 9.2 9.8 NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 112.6;retina: 94.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 58.0;Oligodendrocyte precursor cells: 61.3;Pancreatic endocrine cells: 124.8;Rod photoreceptor cells: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.0;naive CD8 T-cell: 30.7" "Group enriched" "Detected in many" 41 "B-cells: 33.0;T-cells: 30.7" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 807.8;LHCN-M2: 934.3;TIME: 546.2;U-87 MG: 821.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 3000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" 20.7 6.0 9.8 11.9 11.9 0.6 14.1 11.2 10.7 112.6 14.9 29.4 40.1 49.4 6.3 8.6 20.7 17.2 8.7 8.5 11.3 17.2 54.8 6.8 9.6 11.7 14.1 39.3 1.8 1.8 11.8 25.3 13.0 13.3 31.9 94.4 6.6 34.2 2.1 6.4 20.9 73.9 14.7 13.0 8.1 10.4 12.7 5.2 23.7 9.8 11.3 15.8 28.5 12.1 48.9 26.0 42.9 0.8 95.1 302.4 0.4 306.1 332.7 147.5 275.2 0.4 469.6 0.0 107.3 270.2 379.0 24.5 0.1 308.0 348.8 0.8 0.1 0.1 7.3 6.0 47.5 0.2 0.7 77.4 3.7 302.0 191.3 807.8 124.9 0.3 0.3 1.4 934.3 8.3 0.0 0.2 0.8 8.2 34.6 1.5 9.5 1.3 323.1 21.8 0.3 5.5 3.8 18.8 104.9 2.2 0.4 8.3 546.2 120.6 0.9 152.9 506.8 22.7 15.3 0.5 821.7 0.4 385.3 0.0 0.0 0.5 3.7 0.0 6.4 23.7 4.2 11.7 0.0 33.0 4.1 30.7 0.5 0.7 0.0 0.1 1.7 6.4 9.8 11.9 11.2 10.7 8.5 11.3 11.7 14.1 13.0 14.7 12.7 12.1 6.4 0.0 5.8 36.9 21.6 5.2 1.7 6.1 2.8 4.4 1.2 0.3 1.7 27.1 4.8 1.8 10.4 0.6 2.2 49.2 3.9 3.8 0.6 19.3 20.8 20.5 0.0 0.0 1.6 4.1 2.5 39.4 11.2 58.0 0.0 0.1 49.6 33.7 1.3 0.0 2.1 27.7 0.0 3.5 8.2 1.3 13.1 2.1 7.2 11.2 0.5 9.1 0.0 61.3 0.7 124.8 46.0 25.6 3.6 1.5 8.3 27.6 4.8 81.6 0.0 3.3 9.6 0.0 0.3 0.6 4.8 15.2 5.0 0.1 18.0 9.6 NTF3 NGF2 ENSG00000185652 "Neurotrophin 3" P20783 12 5432108-5521536 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 18.5;Basal prostatic cells: 36.6;Basal squamous epithelial cells: 89.4;Prostatic glandular cells: 20.5;Sertoli cells: 32.9;Smooth muscle cells: 24.0" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.2" "Group enriched" "Detected in some" 5 "cerebellum: 3.4;cerebral cortex: 1.3;hippocampal formation: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.4;BJ hTERT+ SV40 Large T+: 14.8;BJ hTERT+ SV40 Large T+ RasG12V: 19.7;HBF TERT88: 18.0;RT4: 8.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebellum: 4.7;cerebral cortex: 2.0;hippocampal formation: 2.2" HPA032001 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA032001: AB_2674106" "unprognostic (3.04e-2)" "unprognostic (7.46e-2)" "unprognostic (7.33e-3)" "unprognostic (4.66e-3)" "unprognostic (8.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.36e-3)" "unprognostic (7.68e-2)" "unprognostic (1.35e-1)" "unprognostic (2.14e-1)" "unprognostic (1.86e-1)" "unprognostic (2.20e-1)" "unprognostic (7.77e-4)" "unprognostic (4.02e-3)" "unprognostic (1.92e-1)" "unprognostic (8.06e-3)" "unprognostic (4.51e-3)" 4.2 1.8 0.2 0.7 0.4 0.0 2.7 3.4 1.3 6.6 0.2 1.8 1.9 1.9 2.0 3.4 2.9 1.8 3.1 1.2 0.3 2.6 7.7 1.6 0.3 0.4 0.2 11.1 0.2 0.1 1.0 1.9 0.3 3.6 1.0 0.1 3.1 2.4 1.8 3.2 2.5 0.9 0.3 4.5 2.5 0.8 0.1 0.4 0.9 1.0 0.4 4.6 7.0 0.2 1.9 0.0 6.7 0.0 0.0 0.0 0.0 4.5 11.4 14.8 19.7 0.1 0.2 0.0 6.7 7.3 0.0 2.4 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 4.5 4.7 8.5 0.3 0.0 0.0 0.1 0.0 3.9 0.0 0.0 0.0 0.0 3.1 0.2 0.0 0.2 0.1 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 3.4 1.3 1.2 0.3 0.4 0.2 0.3 0.3 0.1 0.2 1.0 0.0 0.0 0.0 0.0 18.5 36.6 0.7 89.4 0.0 0.2 10.3 0.9 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.2 0.2 1.4 0.0 0.0 0.1 0.0 0.1 6.1 0.0 0.1 0.0 0.0 5.0 2.1 0.0 0.0 1.2 0.1 0.0 0.0 2.1 0.1 8.4 0.3 7.2 3.7 0.0 0.0 0.0 0.0 0.0 0.0 1.1 10.9 0.0 20.5 0.2 0.0 0.8 0.0 32.9 6.8 24.0 0.5 0.8 5.0 3.3 0.1 0.5 0.5 0.2 6.9 NTF4 "GLC1O, NT-4/5, NTF5" ENSG00000225950 "Neurotrophin 4" P34130 19 49061066-49065054 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 20.1;skeletal muscle: 17.1;skin 1: 31.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 35.6;Basal respiratory cells: 24.0;Basal squamous epithelial cells: 15.4;Breast myoepithelial cells: 24.3;Club cells: 9.5;Cytotrophoblasts: 13.6;Urothelial cells: 11.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 31.1;HBEC3-KT: 11.7;hTCEpi: 50.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049376 Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA049376: AB_2680735" "unprognostic (4.15e-2)" "unprognostic (1.07e-1)" "unprognostic (9.27e-4)" "unprognostic (1.76e-4)" "unprognostic (2.36e-1)" "unprognostic (1.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.73e-2)" "unprognostic (4.87e-3)" "unprognostic (3.90e-4)" "unprognostic (2.97e-1)" "unprognostic (1.40e-3)" "unprognostic (3.71e-2)" "unprognostic (2.49e-1)" "unprognostic (1.89e-2)" "unprognostic (2.46e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 4.3 0.7 0.0 0.0 0.1 3.7 10.8 2.5 0.0 1.0 0.1 0.0 0.1 0.0 3.5 0.0 0.1 0.2 0.2 0.0 0.0 1.6 3.2 0.1 20.1 0.0 0.0 8.2 7.1 17.1 31.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.9 1.5 2.5 1.1 6.5 9.6 0.1 3.9 0.2 0.3 2.1 0.0 0.0 9.3 0.0 0.0 0.1 0.0 3.4 13.8 0.0 3.5 0.0 0.5 31.1 0.1 11.7 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.1 0.0 50.4 0.0 1.6 3.1 0.0 0.1 0.0 0.2 0.4 1.2 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 8.8 0.0 0.1 0.7 0.1 0.0 4.3 8.0 0.1 0.2 1.8 3.5 0.2 9.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 3.2 0.0 0.0 0.0 7.0 35.6 24.0 15.4 0.0 3.4 24.3 0.4 0.0 9.5 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 5.7 0.0 0.0 0.0 0.9 0.0 1.3 1.7 3.1 2.7 0.3 0.1 0.0 11.9 NTM "CEPU-1, HNT, IGLON2, NTRI" ENSG00000182667 Neurotrimin Q9P121 11 131370478-132336822 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 321.8;choroid plexus: 89.2;retina: 74.8" "Group enriched" "Detected in many" 5 "Alveolar cells type 1: 608.9;Astrocytes: 2164.2;Cone photoreceptor cells: 950.8;Excitatory neurons: 651.0;Inhibitory neurons: 1056.6;Oligodendrocyte precursor cells: 1930.7;Oligodendrocytes: 1257.6;Rod photoreceptor cells: 1415.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 175 "plasmacytoid DC: 17.4" "Lineage enriched" "Detected in single" 175 "dendritic cells: 17.4" "Cell line enhanced" "Detected in many" "LHCN-M2: 122.4;U-138 MG: 47.7;U-2 OS: 81.8;WM-115: 166.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB024875 Enhanced "Intracellular and membrane" NA NA 58000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB024875: " "unprognostic (1.52e-2)" "unprognostic (4.38e-3)" "unprognostic (1.61e-2)" "unprognostic (1.89e-1)" "unprognostic (4.25e-1)" "unprognostic (1.07e-1)" "unprognostic (9.99e-3)" "unprognostic (9.61e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-2)" "unprognostic (4.29e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.10e-8)" "unprognostic (4.60e-3)" "unprognostic (1.37e-1)" "unprognostic (2.94e-1)" "unprognostic (9.31e-3)" 17.9 4.7 137.2 2.3 138.8 0.0 2.9 165.1 321.8 1.6 89.2 12.0 2.5 1.3 0.6 9.4 0.9 9.6 30.5 136.9 131.5 2.3 0.3 25.8 0.4 144.0 135.4 0.3 0.9 22.1 0.9 0.7 143.6 1.9 3.8 74.8 2.7 2.8 0.9 6.1 4.6 4.5 135.0 0.5 2.0 0.6 154.2 0.5 1.1 5.0 0.4 3.5 1.8 158.4 0.1 0.0 7.5 0.1 0.9 22.2 0.0 36.7 19.5 11.7 6.8 0.1 0.0 0.0 0.0 20.3 0.0 0.3 0.0 43.6 12.6 0.1 0.4 0.0 0.0 0.4 0.4 0.0 0.2 2.0 0.0 38.0 45.0 29.0 7.5 0.0 0.0 0.3 122.4 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 3.9 20.8 0.0 2.4 3.8 0.0 0.0 0.2 1.3 0.0 0.1 8.1 47.7 81.8 2.2 31.6 0.0 0.0 0.2 0.1 0.0 166.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 137.2 138.8 165.1 321.8 136.9 131.5 144.0 135.4 143.6 135.0 154.2 158.4 1.2 608.9 27.6 2164.2 0.0 1.8 0.0 1.5 2.2 225.3 0.9 4.4 13.7 0.0 29.7 20.2 950.8 0.0 5.4 0.4 0.0 0.6 10.9 0.0 0.5 2.9 0.0 2.7 651.0 0.0 0.0 22.2 0.5 0.0 53.0 0.1 0.7 0.0 0.1 40.4 1056.6 0.1 0.0 0.0 3.8 2.2 0.3 0.7 3.6 139.6 0.0 30.5 0.0 1930.7 1257.6 0.1 0.2 0.4 0.1 0.1 0.0 0.1 1.5 1415.0 0.0 20.6 7.5 0.4 0.9 0.5 4.8 0.0 0.8 0.0 0.8 0.1 NTN1 NTN1L ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;heart muscle: 59.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 137.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 27.5;T-47d: 16.6;U-2 OS: 14.4;U-251 MG: 22.1;WM-115: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" NA NA 110000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" 6.4 0.5 4.5 3.6 6.4 0.1 5.3 10.1 4.9 9.3 2.8 14.7 6.7 9.6 3.5 18.9 10.3 7.3 59.4 3.8 7.0 2.0 6.9 4.3 0.2 12.7 37.1 0.9 2.3 4.3 3.0 0.9 14.4 3.9 3.9 0.4 10.9 2.0 2.1 8.1 10.5 6.0 13.8 0.1 17.5 3.1 10.1 2.9 2.0 2.6 2.1 10.2 5.4 8.8 0.1 0.0 1.3 4.6 4.2 0.1 27.5 0.3 0.4 0.3 0.5 0.1 5.7 0.0 6.2 0.0 9.0 0.1 1.2 0.9 0.0 6.4 10.4 1.4 0.0 0.0 0.1 0.5 0.1 0.1 2.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 5.6 0.1 0.6 1.8 0.0 0.0 3.4 4.8 0.0 0.0 0.3 0.0 0.0 0.1 4.7 1.1 4.5 16.6 0.3 0.0 6.7 14.4 0.0 22.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 6.4 10.1 4.9 3.8 7.0 12.7 37.1 14.4 13.8 10.1 8.8 0.7 0.0 0.0 10.7 0.3 3.3 6.6 21.8 9.6 2.9 4.7 4.4 28.1 0.0 23.9 1.8 0.0 0.3 0.2 0.5 0.0 3.1 9.3 5.8 2.0 3.1 0.0 0.0 4.8 1.7 1.2 9.7 1.1 7.9 0.0 0.0 2.2 12.4 0.1 0.0 7.1 1.4 24.4 0.6 5.9 4.6 0.3 0.1 1.8 9.4 0.6 0.3 0.0 137.2 1.0 1.4 0.1 0.0 0.0 4.0 0.7 0.2 11.1 0.2 0.0 3.9 6.8 1.6 2.0 12.7 2.8 0.5 0.5 0.0 0.6 3.5 NTN3 NTN2L ENSG00000162068 "Netrin 3" O00634 16 2471297-2474145 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "brain: 2.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HeLa: 1.7;REH: 5.0;SCLC-21H: 5.8;SH-SY5Y: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050817 Uncertain "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA050817: AB_2681247" "unprognostic (2.60e-2)" "unprognostic (1.95e-2)" "unprognostic (1.79e-1)" "unprognostic (9.17e-2)" "unprognostic (6.44e-2)" "unprognostic (2.23e-2)" "unprognostic (9.62e-3)" "unprognostic (2.11e-1)" "unprognostic (4.55e-2)" "unprognostic (6.95e-2)" "unprognostic (5.58e-2)" "unprognostic (2.34e-1)" "unprognostic (1.35e-2)" "unprognostic (3.26e-2)" "unprognostic (6.68e-2)" "unprognostic (2.39e-2)" "unprognostic (6.61e-2)" 0.1 0.0 2.2 0.0 1.2 0.0 0.0 0.5 1.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.1 2.3 0.0 0.2 0.0 0.0 2.1 2.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.7 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.7 0.1 0.0 0.0 5.0 0.1 0.1 0.0 0.0 5.8 3.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.3 0.2 0.4 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.2 0.5 1.6 1.1 2.3 2.1 2.0 0.8 1.5 2.7 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NTN4 ENSG00000074527 "Netrin 4" Q9HB63 12 95657807-95791189 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 181.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 198.6;Hepatic stellate cells: 369.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "MAIT T-cell: 1.6" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 513.8;hTERT-HME1: 205.8;PC-3: 189.6;TIME: 289.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA049832 Approved "Secreted to extracellular matrix" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA049832: AB_2680905" "unprognostic (3.08e-1)" "unprognostic (2.17e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (2.11e-2)" "unprognostic (1.42e-1)" "unprognostic (1.67e-1)" "unprognostic (3.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (2.85e-1)" "prognostic favorable (8.12e-9)" "unprognostic (3.52e-2)" "unprognostic (7.08e-2)" "unprognostic (1.93e-1)" "prognostic favorable (6.67e-5)" 24.4 17.3 6.4 5.7 7.5 0.1 72.9 4.4 10.5 26.5 12.0 16.5 12.0 12.7 15.3 15.6 34.4 22.4 66.8 8.9 5.7 107.6 26.7 70.2 2.9 5.9 8.7 86.1 62.5 13.3 7.6 11.9 5.7 42.4 18.1 0.6 32.6 59.1 12.6 8.8 17.5 15.0 6.1 181.5 48.7 12.1 6.2 6.2 14.4 19.9 6.5 49.5 14.4 8.7 26.7 71.3 2.0 0.1 28.5 45.0 3.0 49.7 513.8 67.1 78.2 56.1 48.8 0.0 3.5 105.3 88.1 42.2 0.6 15.3 34.0 0.0 4.3 2.3 12.7 11.1 1.7 0.0 0.1 1.1 43.5 75.0 205.8 72.9 133.3 0.4 0.0 0.1 25.4 20.0 0.2 0.3 1.1 7.9 189.6 0.2 0.6 0.1 64.8 133.4 0.3 0.6 60.5 77.1 1.3 2.3 22.2 0.1 289.3 25.9 9.5 101.3 5.2 0.1 0.1 0.0 5.9 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 7.5 4.4 10.5 8.9 5.7 5.9 8.7 5.7 6.1 6.2 8.7 31.9 41.7 123.2 6.2 3.8 4.7 120.5 15.2 39.3 1.8 77.6 55.4 44.8 44.3 30.8 198.6 0.0 6.2 1.3 4.4 5.9 36.7 10.3 36.4 3.2 35.5 0.0 2.7 28.1 28.0 3.6 33.7 23.0 28.1 1.3 25.9 369.5 10.2 0.4 0.0 70.6 37.2 4.1 26.3 3.7 3.8 2.1 2.6 7.2 20.6 0.6 0.3 0.0 112.6 1.8 36.7 4.0 3.4 0.9 108.9 1.5 84.3 38.0 0.2 26.3 119.0 73.9 1.9 0.6 5.9 2.3 1.6 3.3 1.4 6.4 127.0 NTN5 ENSG00000142233 "Netrin 5" Q8WTR8 19 48661407-48673081 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pituitary gland: 5.1" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Bipolar cells: 5.4;Early spermatids: 9.2;Horizontal cells: 8.4;Late spermatids: 11.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.2" "Region enhanced" "Detected in some" "cerebral cortex: 3.5" "Region enriched" "Detected in single" 5 "cerebellum: 4.8" "Secreted in brain" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (8.20e-3)" "unprognostic (5.54e-2)" "unprognostic (5.26e-6)" "unprognostic (4.48e-2)" "unprognostic (2.23e-1)" "unprognostic (4.33e-2)" "unprognostic (3.18e-2)" "unprognostic (1.73e-2)" "unprognostic (2.89e-3)" "unprognostic (9.40e-3)" "unprognostic (1.74e-3)" "unprognostic (4.60e-1)" "unprognostic (5.11e-2)" "unprognostic (1.60e-3)" "unprognostic (3.51e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-3)" 0.3 0.4 2.0 0.2 2.2 0.3 1.2 1.6 2.8 1.4 0.6 0.6 0.2 1.0 0.5 0.5 3.2 0.7 0.3 1.9 1.4 0.8 0.4 0.4 0.8 1.9 1.8 2.3 0.4 0.5 5.1 0.0 1.5 2.8 0.0 1.2 1.0 0.8 0.2 1.2 0.6 0.1 1.7 0.9 0.3 0.6 1.8 0.6 1.9 0.1 0.3 0.4 0.8 2.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.3 0.5 0.2 0.0 0.0 0.6 0.0 0.2 0.9 0.1 0.0 0.0 0.3 0.2 0.4 0.0 1.2 0.0 0.3 0.3 0.2 0.0 0.0 0.6 0.1 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.2 1.6 2.8 1.9 1.4 1.9 1.8 1.5 1.7 1.8 2.2 1.1 0.0 0.0 4.6 0.1 0.5 0.4 0.1 0.0 5.4 0.8 1.9 0.3 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.1 9.2 0.5 1.3 0.6 0.0 0.0 1.1 0.0 0.0 0.4 0.0 1.0 0.0 2.3 0.4 0.1 0.1 8.4 0.6 0.1 0.0 0.0 0.4 11.8 0.6 0.1 1.8 1.0 0.0 1.6 1.0 0.0 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 2.8 0.0 0.7 0.4 3.1 0.2 0.1 0.1 0.1 0.2 3.1 0.0 0.2 NTNG1 "KIAA0976, Lmnt1" ENSG00000162631 "Netrin G1" Q9Y2I2 1 107140007-107484923 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 75.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.7;Excitatory neurons: 122.1;Inhibitory neurons: 162.5;Oligodendrocyte precursor cells: 425.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "thalamus: 75.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 48.7;fHDF/TERT166: 25.0;RPTEC TERT1: 27.4;U-138 MG: 21.8;U-251 MG: 16.9;U-87 MG: 24.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "hippocampal formation: 19.7;midbrain: 61.3;pons: 56.0;thalamus: 76.4" HPA065954 Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA065954: AB_2685585" "unprognostic (1.79e-1)" "unprognostic (4.63e-2)" "unprognostic (1.67e-2)" "unprognostic (9.38e-5)" "unprognostic (1.93e-3)" "unprognostic (9.87e-3)" "unprognostic (3.34e-1)" "unprognostic (8.38e-3)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "unprognostic (2.05e-2)" "unprognostic (3.10e-4)" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (1.93e-5)" 3.1 4.4 17.2 0.2 3.8 0.0 0.2 6.3 6.7 3.2 0.0 2.2 0.0 0.6 0.0 0.1 0.4 0.6 0.1 7.8 15.2 8.8 0.0 3.8 0.4 5.8 28.3 0.4 0.1 0.1 2.5 1.1 4.6 3.4 0.4 10.3 0.2 4.7 0.0 1.3 0.4 0.1 3.2 0.3 0.2 0.4 75.1 0.5 0.1 0.2 0.6 4.0 1.8 2.7 0.0 0.0 2.8 0.0 5.0 48.7 0.0 13.9 2.1 1.2 1.1 0.0 0.0 0.0 0.6 25.0 0.0 0.0 0.0 1.5 2.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 13.9 0.3 3.5 1.8 14.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.0 0.0 6.1 0.0 3.1 0.0 27.4 0.0 0.3 0.4 0.0 0.0 0.0 0.8 0.0 0.1 0.2 21.8 4.3 8.1 16.9 0.1 0.0 0.0 24.8 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.0 17.2 3.8 6.3 6.7 7.8 15.2 5.8 28.3 4.6 3.2 75.1 2.7 0.2 0.0 0.0 46.4 3.1 0.5 6.5 0.4 0.0 59.7 0.1 0.0 0.9 0.0 0.2 7.3 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.1 0.8 0.9 0.0 0.0 122.1 0.0 0.0 2.8 0.0 0.4 0.0 6.1 0.4 0.0 0.0 0.0 162.5 0.0 6.1 0.0 1.3 1.8 8.1 0.0 1.8 18.7 0.0 1.0 0.0 425.3 2.5 0.3 0.0 0.0 1.0 1.1 0.0 0.0 0.0 2.9 6.6 0.2 2.7 0.2 1.1 0.1 0.6 0.0 0.1 7.2 0.0 4.3 NTNG2 "KIAA1857, Lmnt2, NTNG1" ENSG00000196358 "Netrin G2" Q96CW9 9 132161676-132244526 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Autism spectrum disorder, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 40.4;brain: 74.6;retina: 26.7" "Cell type enhanced" "Detected in many" "Astrocytes: 34.9;Bipolar cells: 69.6;Cone photoreceptor cells: 171.0;Rod photoreceptor cells: 108.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "basal ganglia: 74.6" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "HL-60: 6.8;HMC-1: 16.2;NB-4: 39.0;U-937: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071290 Approved "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA071290: AB_2686381" "unprognostic (5.01e-2)" "unprognostic (2.95e-2)" "unprognostic (4.12e-2)" "unprognostic (1.01e-1)" "unprognostic (3.59e-1)" "unprognostic (7.67e-2)" "unprognostic (2.73e-2)" "unprognostic (2.87e-1)" "unprognostic (4.86e-2)" "unprognostic (1.47e-1)" "unprognostic (2.62e-2)" "prognostic favorable (6.06e-4)" "unprognostic (9.30e-12)" "unprognostic (1.66e-1)" "unprognostic (3.23e-1)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" 0.6 1.9 18.6 1.1 74.6 40.4 0.2 13.3 25.6 0.8 0.0 0.5 1.2 0.5 0.3 0.3 0.5 0.8 5.5 17.6 6.5 0.7 0.3 2.9 1.4 11.5 5.4 0.2 1.0 4.4 1.7 0.5 14.7 6.2 0.2 26.7 0.8 1.1 0.4 0.4 0.8 0.3 5.0 3.9 0.6 2.1 11.4 0.5 0.4 1.4 0.4 0.8 0.6 11.5 0.0 0.5 0.2 0.6 0.6 0.1 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 2.9 0.0 0.2 0.0 0.0 1.1 0.2 0.1 0.1 0.0 0.9 6.8 16.2 0.1 0.0 0.2 0.1 1.4 0.0 1.3 0.0 0.0 0.5 0.2 0.3 39.0 1.4 0.0 0.2 0.4 0.4 0.2 0.0 0.0 4.6 4.2 0.2 0.0 0.1 0.0 0.0 0.6 0.1 0.9 2.8 3.6 0.1 0.1 0.0 0.0 1.3 10.0 1.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 18.6 74.6 13.3 25.6 17.6 6.5 11.5 5.4 14.7 5.0 11.4 11.5 0.8 0.0 0.6 34.9 0.5 0.3 0.6 0.0 0.6 69.6 0.1 1.0 3.0 0.0 0.6 0.0 171.0 0.1 5.0 0.0 0.0 0.3 1.4 0.6 2.4 1.3 0.0 0.4 8.1 0.0 0.0 1.9 0.0 1.1 1.3 0.9 0.7 0.1 0.7 1.7 3.6 0.2 0.0 0.3 0.3 1.3 0.6 1.2 1.8 8.4 0.9 20.3 3.1 11.1 21.5 0.1 0.0 1.2 2.0 2.3 0.0 0.1 0.0 108.3 6.6 2.4 1.8 0.5 0.2 0.2 0.3 0.1 1.2 4.3 0.1 0.3 NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815640-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 7.0;brain: 21.7" "Group enriched" "Detected in some" 10 "Bipolar cells: 22.8;granulocytes: 55.9;Horizontal cells: 57.2" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Group enriched" "Detected in many" 6 "cerebral cortex: 7.6;medulla oblongata: 19.8;pons: 21.7" "Immune cell enriched" "Detected in single" 116 "basophil: 94.5" "Lineage enriched" "Detected in single" 768 "granulocytes: 94.5" "Cell line enriched" "Detected in some" 4 "HMC-1: 82.1" "Region enhanced" "Detected in many" "basal ganglia: 8.4" "Region enriched" "Detected in single" 6 "basal ganglia: 4.1" "CAB004606, HPA035799, HPA076570" Approved Approved Vesicles,Cytosol NA NA 79000 "Cluster 38: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Cytosol" "CAB004606: AB_628397, HPA035799: AB_2674788, HPA076570: " "unprognostic (5.89e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-2)" "unprognostic (5.99e-3)" "unprognostic (7.26e-2)" "unprognostic (1.43e-3)" "unprognostic (1.56e-1)" "unprognostic (7.42e-3)" "unprognostic (7.63e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-11)" "unprognostic (2.18e-3)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" 0.8 7.0 0.7 0.4 1.8 0.7 0.2 1.8 7.6 0.7 0.7 0.8 0.5 1.0 0.0 0.1 0.5 0.4 1.0 0.3 2.8 3.0 0.0 0.5 0.1 19.8 1.5 0.1 0.2 0.0 0.7 0.2 21.7 1.4 0.0 1.9 0.5 0.3 0.4 0.1 0.3 0.6 0.2 0.1 0.5 1.6 0.4 0.3 0.2 0.2 0.0 0.3 0.5 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 11.9 0.0 14.0 0.0 0.0 0.0 0.0 82.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.4 1.6 0.0 0.2 0.0 2.4 0.2 0.0 1.5 2.5 0.0 0.2 0.0 0.5 1.5 18.2 0.0 0.1 0.0 0.3 0.0 0.1 0.3 0.0 1.1 0.0 0.0 3.5 0.6 0.0 0.0 0.0 0.1 94.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.7 1.8 1.8 7.6 0.3 2.8 19.8 1.5 21.7 0.2 0.4 0.6 0.1 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 4.2 0.7 0.0 0.0 4.3 0.0 0.1 55.9 0.0 0.0 0.0 0.1 57.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.9 3.2 2.7 0.0 0.1 0.0 1.0 0.1 0.0 0.0 NTS ENSG00000133636 Neurotensin P30990 12 85874295-85882992 "Predicted secreted proteins" Vasoactive "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 165.8" "Cell type enriched" "Detected in some" 13 "Intestinal goblet cells: 1683.2" "Cancer enhanced" "Detected in many" "lung cancer: 155.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 205.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 154.3" "HPA026664, HPA071012" Enhanced Supported Vesicles "Secreted to digestive system" NA NA 1600000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "HPA026664: AB_2671936, HPA071012: " "unprognostic (3.63e-1)" "prognostic favorable (9.94e-5)" "unprognostic (8.18e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (7.62e-2)" "unprognostic (2.43e-1)" "unprognostic (1.53e-3)" "unprognostic (8.83e-2)" "unprognostic (1.74e-2)" "unprognostic (3.76e-2)" "unprognostic (1.30e-6)" "unprognostic (2.94e-2)" "unprognostic (2.25e-1)" "unprognostic (2.17e-1)" "unprognostic (7.48e-2)" 6.2 1.2 3.3 3.6 0.6 0.0 5.2 0.9 8.4 0.7 0.5 1.8 6.6 0.3 0.7 5.6 0.9 1.3 0.9 2.5 18.1 1.7 1.4 1.2 11.7 11.7 10.2 0.6 0.4 0.1 32.3 0.5 6.2 0.3 1.5 0.0 0.1 0.6 0.0 0.2 165.8 1.1 3.2 0.1 36.4 0.3 26.8 0.5 0.8 0.2 1.0 3.1 0.3 3.6 0.0 5.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 0.0 0.0 0.0 0.0 1.0 50.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 10.7 0.0 4.1 0.0 1.7 0.0 0.0 0.0 5.4 1.6 0.0 0.0 0.0 205.5 0.4 0.0 0.0 0.1 0.0 0.4 0.0 2.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.6 0.9 8.4 2.5 18.1 11.7 10.2 6.2 3.2 26.8 3.6 3.6 0.0 0.5 0.0 0.0 1.3 0.7 22.6 0.0 0.0 10.1 0.0 0.3 0.0 27.0 9.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.4 2.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 44.3 0.0 0.2 0.0 1.2 1683.2 2.0 0.3 2.6 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.5 15.0 0.0 0.0 2.5 120.8 0.0 3.5 0.0 0.0 0.0 0.9 0.8 0.1 1.2 2.3 0.1 1.3 0.0 8.1 60.4 NUBP2 "CFD1, CIAO6" ENSG00000095906 "Nucleotide binding protein 2" Q9Y5Y2 16 1782932-1789186 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041704 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "HPA041704: AB_10804006" "unprognostic (1.94e-1)" "unprognostic (5.73e-3)" "unprognostic (2.83e-1)" "unprognostic (1.17e-1)" "unprognostic (2.16e-1)" "unprognostic (6.02e-2)" "unprognostic (8.44e-2)" "unprognostic (1.21e-1)" "unprognostic (3.42e-1)" "unprognostic (1.53e-1)" "unprognostic (8.64e-2)" "unprognostic (1.20e-1)" "prognostic favorable (9.63e-5)" "unprognostic (2.92e-2)" "unprognostic (1.82e-1)" "unprognostic (2.21e-1)" "unprognostic (5.83e-2)" 19.4 34.3 18.2 10.6 19.7 16.6 17.6 19.5 25.5 21.6 26.5 21.9 14.5 18.7 3.8 30.8 17.1 5.9 20.8 17.6 17.1 26.4 53.2 18.0 16.0 21.3 18.4 17.7 34.2 8.3 18.7 10.9 18.9 25.6 4.2 3.4 22.4 10.4 27.9 25.8 20.5 6.7 18.9 26.8 27.2 10.1 19.7 14.0 18.9 8.2 6.4 20.8 20.1 19.8 28.6 91.4 16.2 49.6 12.1 9.2 50.9 32.2 14.8 20.7 23.3 56.1 41.5 45.0 38.1 7.4 15.2 32.6 10.8 31.6 3.8 39.6 85.7 19.6 67.2 83.0 23.6 30.2 38.2 13.1 26.6 16.9 12.1 13.0 26.2 54.9 49.4 29.6 8.7 109.1 58.8 53.7 44.2 26.4 52.6 80.0 33.4 106.1 16.7 21.1 58.4 70.4 31.9 50.4 38.1 4.2 75.5 35.9 29.8 33.8 42.6 31.9 34.1 65.1 44.9 54.4 20.4 36.0 44.2 72.3 58.1 59.8 64.9 61.6 59.2 48.5 56.5 57.7 62.3 47.6 47.1 45.0 29.7 57.9 60.7 87.5 84.2 67.9 18.2 19.7 19.5 25.5 17.6 17.1 21.3 18.4 18.9 18.9 19.7 19.8 41.0 16.0 30.9 9.4 38.4 35.8 39.4 75.8 24.5 36.0 52.2 65.9 24.9 42.9 43.7 31.3 20.9 103.9 55.5 40.2 66.5 64.7 33.1 23.1 32.7 35.1 38.2 36.4 6.2 74.3 83.0 38.0 32.6 24.5 20.3 48.6 31.8 65.0 62.2 23.5 7.4 51.7 54.9 39.3 28.8 90.9 36.7 27.9 58.7 7.5 55.1 54.4 68.0 6.0 11.0 63.7 30.4 30.9 38.0 45.0 65.4 67.1 22.2 42.5 46.0 28.2 43.3 34.0 30.6 44.7 41.5 41.3 42.0 49.6 58.2 32.2 NUBPL "C14orf127, FLJ12660, huInd1, IND1" ENSG00000151413 "Nucleotide binding protein like" Q8TB37 14 31489956-31861224 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 68.2;Inhibitory neurons: 74.8;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029203 Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA029203: AB_10602810" "unprognostic (1.49e-1)" "unprognostic (1.71e-2)" "unprognostic (5.21e-3)" "unprognostic (8.28e-2)" "unprognostic (8.25e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "unprognostic (1.93e-2)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "prognostic favorable (3.64e-8)" "unprognostic (2.82e-2)" "unprognostic (6.60e-2)" "unprognostic (3.67e-3)" "unprognostic (1.56e-2)" 9.7 6.4 4.2 3.9 4.6 1.8 8.9 4.5 4.8 4.9 4.2 7.6 4.9 5.8 7.6 4.6 6.4 5.3 17.0 4.0 5.0 12.2 12.3 4.1 5.7 4.9 4.7 6.8 5.5 7.9 3.8 5.5 4.5 6.3 7.8 5.2 11.9 6.1 11.9 4.7 5.8 5.4 4.3 6.6 4.7 3.5 5.0 5.5 8.0 17.4 5.4 4.2 3.2 5.8 13.6 8.5 6.4 3.3 8.9 16.4 11.5 7.3 8.2 8.9 10.2 5.9 15.3 9.8 9.2 9.1 7.5 11.7 8.6 15.5 15.3 7.1 11.1 3.5 6.3 30.4 8.8 10.4 3.0 10.7 17.0 6.0 12.8 7.3 5.0 7.0 6.4 4.9 9.8 7.4 7.7 7.1 5.4 10.8 13.1 8.6 13.4 5.3 10.2 10.0 6.0 6.2 12.2 10.8 14.5 7.2 21.1 5.4 4.9 8.6 5.9 5.6 6.8 8.1 9.7 9.3 5.5 7.3 7.9 0.0 1.1 0.4 2.1 1.2 1.7 2.6 2.7 2.3 4.4 1.7 3.0 2.4 0.4 2.5 0.7 2.2 1.8 0.9 4.2 4.6 4.5 4.8 4.0 5.0 4.9 4.7 4.5 4.3 5.0 5.8 6.9 12.8 9.8 68.2 10.1 9.6 8.6 5.4 9.1 15.3 10.2 7.1 36.9 15.7 10.6 9.2 20.9 11.2 7.5 6.3 7.9 6.8 24.1 12.6 10.8 6.3 7.2 6.7 48.2 5.7 10.2 12.0 7.1 5.4 14.5 16.4 4.6 15.3 4.9 10.1 74.8 12.0 2.0 4.1 16.1 7.4 6.5 6.1 12.4 54.4 2.8 16.2 5.2 87.9 99.6 5.2 5.8 11.7 8.0 4.4 5.1 19.1 18.7 28.4 13.1 11.8 9.8 15.7 5.2 7.3 11.6 5.7 6.4 23.1 18.2 5.9 NUCB1 "Calnuc, NUC" ENSG00000104805 "Nucleobindin 1" Q02818 19 48900312-48923372 "Plasma proteins, Predicted secreted proteins" "DNA-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 453.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008176 Supported Supported "Golgi apparatus,Microtubules" "Secreted to blood" NA NA 27000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" Microtubules "HPA008176: AB_1845923" "unprognostic (2.13e-1)" "unprognostic (2.83e-1)" "unprognostic (4.36e-3)" "unprognostic (6.28e-2)" "unprognostic (1.06e-2)" "unprognostic (2.95e-1)" "unprognostic (6.86e-2)" "unprognostic (1.98e-1)" "unprognostic (9.51e-2)" "unprognostic (8.14e-3)" "unprognostic (2.34e-3)" "unprognostic (9.89e-2)" "unprognostic (5.04e-3)" "unprognostic (1.19e-1)" "unprognostic (1.39e-1)" "unprognostic (8.90e-3)" "unprognostic (3.41e-1)" 181.3 103.5 55.8 106.8 60.4 82.3 141.6 65.5 68.1 115.0 79.4 122.1 179.9 127.6 61.3 111.2 116.9 108.3 204.0 58.2 63.0 154.6 264.5 157.1 82.1 65.9 62.9 125.6 130.1 173.5 69.5 114.8 67.5 109.2 54.8 30.2 117.8 103.0 180.1 96.6 163.6 106.0 57.7 111.1 118.8 34.7 73.1 49.5 122.2 110.7 53.1 130.1 108.9 61.6 54.8 182.1 84.2 188.5 304.6 249.2 97.6 208.1 189.9 103.3 144.2 92.9 203.1 54.7 151.8 250.6 98.9 132.0 48.6 107.0 43.3 194.6 90.3 141.6 119.0 131.6 156.6 85.1 183.6 288.0 52.1 96.8 62.9 275.2 167.2 60.7 173.1 278.8 107.0 71.6 42.3 68.6 42.2 132.1 93.5 78.7 125.3 114.9 90.2 134.6 61.2 123.2 247.1 152.2 88.1 79.7 78.8 112.1 234.6 172.3 114.3 107.0 99.3 210.8 501.1 37.1 132.5 54.3 207.3 102.9 108.5 105.7 100.6 128.5 75.3 46.8 67.5 77.2 79.0 37.3 55.3 56.7 104.7 69.2 114.2 113.9 74.6 129.5 55.8 60.4 65.5 68.1 58.2 63.0 65.9 62.9 67.5 57.7 73.1 61.6 154.5 41.7 72.1 17.6 51.0 48.3 67.2 81.3 66.0 21.7 57.6 57.5 58.0 78.6 51.5 69.9 14.6 101.5 69.6 153.0 41.1 148.0 10.8 27.4 65.5 116.0 74.4 54.5 14.5 118.3 150.9 126.7 76.0 50.2 95.2 64.1 122.0 149.2 213.7 20.2 18.9 109.9 69.2 138.3 74.6 9.3 110.3 101.9 101.4 17.8 120.3 52.6 74.2 8.5 11.8 100.0 149.2 124.1 126.3 63.8 453.3 135.4 24.4 20.5 92.1 51.0 79.0 21.9 37.6 65.6 49.9 102.1 73.0 103.9 123.3 68.1 NUCB2 NEFA ENSG00000070081 "Nucleobindin 2" P80303 11 17208153-17349980 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "DNA-binding, Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 758.3;salivary gland: 771.4" "Cell type enhanced" "Detected in all" "Early spermatids: 690.6;Late spermatids: 508.5;Respiratory ciliated cells: 618.8;Syncytiotrophoblasts: 1158.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 1867.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008395, CAB015931, CAB079781" Enhanced Supported Enhanced "Golgi apparatus" "Secreted to blood" NA NA 1250000 690000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Golgi apparatus" "CAB015931: , CAB079781: AB_2313672, HPA008395: AB_1854683" "unprognostic (2.49e-1)" "unprognostic (1.75e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.27e-6)" "unprognostic (5.24e-3)" "unprognostic (2.51e-1)" "unprognostic (3.96e-3)" "unprognostic (3.66e-3)" "unprognostic (1.81e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.46e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (2.39e-1)" "unprognostic (1.61e-1)" "unprognostic (4.78e-2)" "unprognostic (8.02e-3)" 56.2 75.7 23.9 62.1 27.8 619.9 141.1 28.8 32.1 137.2 58.0 68.3 57.3 60.8 458.2 146.3 107.2 60.8 95.7 22.8 34.7 43.2 102.2 49.8 60.2 25.7 28.2 56.0 758.3 479.1 113.0 90.9 26.8 70.9 68.4 64.5 771.4 190.9 38.5 21.1 40.7 78.5 26.2 42.2 92.9 119.2 28.4 334.2 153.9 30.4 78.5 61.8 44.9 26.6 119.9 49.0 53.7 163.4 118.9 162.3 65.0 260.5 381.0 115.1 203.0 48.7 26.8 182.9 63.5 250.7 107.1 50.1 34.4 66.8 178.7 126.7 76.3 135.8 57.8 85.2 340.5 1867.0 238.6 71.1 86.8 82.9 200.9 284.9 143.3 672.1 120.1 361.1 114.9 105.9 656.2 670.3 12.9 194.0 50.5 239.8 130.4 15.1 51.9 37.5 63.5 35.4 114.6 114.2 61.4 78.0 93.5 498.1 128.1 120.9 110.9 369.1 112.1 70.3 41.3 101.1 140.5 646.1 106.4 210.5 43.5 168.2 94.1 30.5 122.9 22.7 88.5 173.7 40.6 14.5 246.7 271.2 39.3 277.9 25.6 426.0 42.7 119.8 23.9 27.8 28.8 32.1 22.8 34.7 25.7 28.2 26.8 26.2 28.4 26.6 118.7 44.8 70.4 16.3 54.8 27.5 60.2 156.3 14.8 71.0 152.8 87.0 193.8 55.8 176.5 42.3 54.2 127.1 136.5 17.6 27.4 91.1 690.6 112.4 92.9 94.7 42.4 137.8 21.9 132.6 319.1 148.8 40.2 97.0 67.6 80.0 108.5 141.8 70.7 35.3 23.5 189.0 189.2 29.4 40.0 508.5 149.8 37.6 69.4 18.7 24.1 111.2 95.8 13.6 10.8 75.2 13.2 114.3 256.5 108.7 3.9 28.5 618.8 99.3 46.0 50.8 75.4 174.9 61.3 87.7 30.1 1158.2 92.3 88.3 45.3 61.2 NUDT19 RP2 ENSG00000213965 "Nudix hydrolase 19" A8MXV4 19 32691961-32713796 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042761 Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 49: Eosinophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: U-937 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "HPA042761: " "unprognostic (1.20e-1)" "unprognostic (2.90e-1)" "unprognostic (2.35e-3)" "unprognostic (6.61e-3)" "unprognostic (2.62e-2)" "unprognostic (2.44e-1)" "unprognostic (6.18e-3)" "unprognostic (1.97e-1)" "unprognostic (3.14e-2)" "unprognostic (2.19e-1)" "unprognostic (2.99e-1)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (2.64e-2)" "unprognostic (2.81e-1)" "unprognostic (1.23e-1)" "prognostic favorable (1.35e-4)" 5.1 11.7 4.0 4.1 4.1 8.4 4.6 3.9 4.5 3.9 9.4 6.9 7.1 3.6 5.4 11.1 3.6 2.9 10.6 4.1 5.1 6.3 6.9 6.4 5.8 4.6 4.3 3.7 8.4 7.1 4.0 4.5 4.8 7.5 7.3 8.3 6.9 3.5 23.9 8.9 6.2 4.3 4.3 5.2 8.1 2.8 4.6 3.1 3.6 13.0 5.1 6.3 5.6 4.6 21.5 24.7 2.7 24.0 8.1 10.5 0.2 11.9 4.4 8.7 8.2 14.0 11.6 0.1 14.0 13.8 6.7 13.7 16.7 13.9 11.4 24.8 10.0 27.7 9.3 5.0 11.2 20.9 8.2 8.5 18.1 7.4 17.8 10.1 13.0 4.2 21.6 15.3 15.9 14.3 0.1 19.3 2.9 5.9 11.5 0.1 5.2 12.1 14.4 15.7 10.7 15.4 21.2 17.7 15.9 4.7 9.8 25.4 10.4 11.9 7.7 12.0 21.5 17.8 16.3 6.9 14.4 20.0 11.2 11.1 26.5 15.4 18.2 36.7 20.0 13.0 18.9 22.6 19.5 9.4 14.9 20.4 5.1 32.2 42.4 15.9 23.6 11.9 4.0 4.1 3.9 4.5 4.1 5.1 4.6 4.3 4.8 4.3 4.6 4.6 5.9 12.8 14.5 7.5 6.4 21.9 9.4 4.6 8.0 14.5 12.0 6.6 22.8 2.8 6.2 7.3 12.5 11.0 9.1 10.6 27.4 2.9 7.7 8.5 9.3 7.3 12.1 10.3 5.9 11.5 11.5 6.6 3.1 10.7 1.3 11.3 13.2 12.5 14.3 3.3 6.7 12.7 8.2 17.6 11.6 3.7 4.1 10.2 12.4 4.7 10.7 4.6 4.1 6.6 7.4 12.0 13.1 9.4 4.1 12.0 15.7 18.8 6.5 30.4 0.0 6.9 7.4 1.6 2.2 9.9 31.5 7.8 9.1 22.3 18.4 10.6 NUDT9 MGC3037 ENSG00000170502 "Nudix hydrolase 9" Q9BW91 4 87422573-87459455 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 160.7" "Low region specificity" "Detected in all" "HPA036917, HPA044866, HPA078535" Approved Approved "Nuclear membrane,Nuclear bodies,Cell Junctions,Mitochondria" "Intracellular and membrane" NA NA 9900 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear bodies, Mitochondria" "Nuclear membrane, Cell Junctions" "HPA036917: AB_10696790, HPA044866: AB_2679120, HPA078535: AB_2686885" "unprognostic (7.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.45e-2)" "prognostic favorable (7.43e-5)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (3.47e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.09e-2)" "unprognostic (4.23e-1)" "prognostic favorable (8.00e-11)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (1.19e-1)" "unprognostic (5.77e-3)" 23.6 36.1 20.8 16.2 21.4 6.7 19.7 25.5 38.5 27.6 39.1 27.0 42.6 24.8 32.2 19.6 24.9 16.2 28.8 21.9 24.7 40.4 46.6 23.0 13.7 21.0 20.5 26.7 67.6 55.3 29.1 19.9 21.9 30.4 27.1 20.1 28.1 23.8 42.1 16.6 40.3 23.8 19.6 14.7 22.3 22.5 22.1 13.4 28.8 45.0 14.8 22.4 24.3 26.0 30.8 25.6 34.0 19.8 67.6 39.6 26.0 59.8 35.6 21.3 21.1 17.1 53.1 47.6 58.9 47.6 41.0 21.1 32.1 38.1 33.2 34.5 24.0 13.4 34.5 31.8 42.4 25.6 21.2 41.5 52.4 25.6 22.6 45.5 41.6 13.7 40.3 30.0 38.7 33.4 39.1 23.2 29.1 68.5 12.0 45.0 31.8 27.0 160.7 24.2 41.3 28.7 37.6 63.0 30.8 44.5 36.8 38.2 43.7 34.7 34.3 25.8 27.8 21.5 18.7 37.9 51.3 21.9 48.2 1.6 17.9 5.9 19.1 21.2 18.2 22.2 18.5 19.5 21.4 18.8 22.5 26.0 1.8 15.6 24.0 20.6 19.0 16.0 20.8 21.4 25.5 38.5 21.9 24.7 21.0 20.5 21.9 19.6 22.1 26.0 32.6 67.3 44.8 20.2 14.9 9.9 40.4 45.0 9.6 15.3 11.3 13.1 40.9 30.0 55.0 23.9 27.1 33.2 13.1 21.0 41.1 44.7 28.6 26.0 26.2 25.8 16.8 6.7 21.7 36.5 32.5 29.4 8.6 27.0 20.8 23.3 18.2 47.5 33.2 6.7 24.0 18.0 40.7 12.7 11.0 11.5 25.4 14.7 10.6 20.6 16.4 26.8 8.2 18.6 24.8 29.4 37.0 26.7 15.8 32.9 55.7 56.2 41.0 18.6 26.3 36.9 23.7 44.5 23.6 15.7 9.5 37.6 12.1 29.8 24.9 27.3 NUMA1 ENSG00000137497 "Nuclear mitotic apparatus protein 1" Q14980 11 72002864-72080693 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019841, HPA019859, HPA029912" Enhanced Supported Nucleoplasm,Cytosol NA Yes 62000 "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA019841: AB_1854708, HPA019859: AB_1854709, HPA029912: AB_10602811" "unprognostic (1.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.06e-2)" "unprognostic (2.84e-1)" "unprognostic (1.14e-1)" "unprognostic (6.47e-2)" "unprognostic (5.75e-2)" "unprognostic (8.74e-3)" "unprognostic (5.91e-2)" "unprognostic (9.45e-2)" "unprognostic (1.60e-2)" "unprognostic (2.51e-2)" "prognostic favorable (7.92e-4)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (1.49e-1)" "unprognostic (1.39e-1)" 55.2 59.9 27.8 51.1 45.6 69.6 67.1 37.4 40.5 75.4 36.2 77.7 59.6 111.2 43.3 67.9 82.7 62.7 47.6 24.0 33.0 49.9 29.8 65.4 57.9 40.4 34.3 112.3 68.8 98.6 42.1 60.8 41.9 111.4 54.5 46.2 78.1 85.6 82.5 93.8 61.9 86.7 28.4 56.8 59.0 42.4 36.0 79.3 73.9 54.8 53.2 75.2 65.9 83.4 64.4 80.0 97.2 66.4 85.1 88.2 48.8 85.0 97.2 86.4 74.6 83.9 115.5 86.7 72.0 104.0 61.6 134.2 89.7 85.8 78.0 89.9 43.1 105.8 130.4 64.1 69.1 81.1 74.0 94.0 55.7 84.1 84.3 133.0 74.0 76.7 63.4 101.1 59.4 124.2 105.6 45.2 61.2 122.3 57.6 127.9 170.0 67.6 64.2 98.6 117.3 166.6 134.9 123.5 123.6 42.3 166.4 47.1 103.0 90.6 69.9 130.1 56.9 64.8 69.7 120.0 61.1 38.0 53.0 3.7 4.1 1.9 6.4 2.3 4.7 3.4 4.0 5.0 3.5 5.8 4.9 3.6 2.8 5.0 4.4 8.2 5.2 6.0 27.8 45.6 37.4 40.5 24.0 33.0 40.4 34.3 41.9 28.4 36.0 83.4 52.4 41.7 41.3 42.7 36.6 25.9 30.1 25.3 74.0 60.7 62.3 63.4 5.7 34.3 32.2 53.3 73.0 25.5 42.6 56.3 17.6 27.9 31.9 55.5 48.5 44.9 47.4 43.3 27.5 32.1 13.4 41.9 57.6 92.8 31.0 84.7 37.9 23.6 28.7 52.2 34.0 68.3 32.6 32.1 24.9 17.8 69.0 36.3 19.6 33.7 26.8 51.8 53.5 27.6 58.9 30.9 31.2 50.8 40.8 29.6 57.0 26.9 35.4 59.8 39.5 64.3 36.9 14.8 21.4 51.9 28.1 45.0 44.8 44.2 52.2 26.0 NUP155 "KIAA0791, N155" ENSG00000113569 "Nucleoporin 155" O75694 5 37288137-37371106 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Atrial fibrillation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 70.8" "Cell type enhanced" "Detected in many" "Early spermatids: 64.6;Late spermatids: 104.5;Spermatocytes: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037775 Enhanced Enhanced "Nuclear membrane" "Intracellular and membrane" NA NA 28000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" "HPA037775: AB_10671885" "unprognostic (1.10e-2)" "unprognostic (7.94e-2)" "unprognostic (1.28e-2)" "unprognostic (8.58e-3)" "unprognostic (7.14e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (1.35e-6)" "unprognostic (2.18e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (2.51e-2)" "unprognostic (9.49e-2)" "unprognostic (1.49e-2)" "unprognostic (6.80e-2)" "unprognostic (2.27e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" 5.3 3.4 1.9 6.7 2.7 15.2 7.4 5.1 2.5 5.2 3.3 5.6 4.9 6.0 2.7 6.5 5.2 4.0 4.0 2.1 2.5 4.6 5.7 4.2 8.3 2.5 2.4 6.3 4.8 8.1 2.1 8.1 2.9 5.2 6.9 6.6 4.4 4.2 4.3 5.1 4.5 6.6 2.5 5.7 5.0 70.8 2.8 12.6 6.1 5.9 9.8 5.7 3.5 4.0 40.6 31.7 33.7 50.0 10.3 15.1 120.8 32.2 16.9 43.1 31.4 46.9 32.5 46.0 14.4 20.9 46.7 32.2 57.5 31.7 67.0 30.4 32.3 35.8 109.6 21.9 13.0 60.0 24.0 11.1 13.0 66.5 33.5 11.8 23.2 20.4 65.8 23.8 29.0 19.9 32.4 16.3 32.0 24.8 28.4 38.3 106.1 36.5 9.7 38.5 40.6 27.8 74.0 31.4 18.1 23.8 38.8 23.5 20.2 51.5 42.9 39.3 49.5 26.8 47.9 60.0 24.1 53.0 39.9 4.3 2.0 3.5 3.3 4.2 5.6 3.9 3.1 2.9 2.9 2.9 3.0 3.5 0.6 4.5 3.1 2.0 2.4 2.7 1.9 2.7 5.1 2.5 2.1 2.5 2.5 2.4 2.9 2.5 2.8 4.0 11.1 3.2 6.8 11.8 15.5 10.5 6.5 6.5 10.8 8.0 8.0 5.0 11.0 2.8 9.6 3.7 6.2 14.3 9.8 5.2 0.0 6.0 64.6 6.9 11.0 9.6 1.2 10.7 12.4 6.1 20.4 9.0 9.2 7.1 5.1 15.1 13.9 9.7 7.9 5.0 12.6 8.7 12.2 8.9 8.0 104.5 11.1 7.0 0.0 7.5 5.7 3.9 8.2 15.1 16.7 8.2 3.8 10.1 12.7 7.6 3.9 4.1 11.4 14.5 0.0 11.5 10.5 48.2 21.1 10.8 11.6 7.5 9.9 10.6 11.3 4.9 NUP214 "CAIN, CAN, D9S46E, N214" ENSG00000126883 "Nucleoporin 214" P35658 9 131125586-131234663 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 124.2" "Cell type enhanced" "Detected in all" "Early spermatids: 281.4;Granulosa cells: 169.2;Kupffer cells: 274.8;Late spermatids: 404.3;monocytes: 224.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 425.3;neutrophil: 1259.6" "Group enriched" "Detected in all" 5 "granulocytes: 1259.6;monocytes: 425.3" "Cell line enhanced" "Detected in all" "K-562: 260.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 46000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.30e-1)" "unprognostic (9.51e-3)" "unprognostic (9.92e-3)" "unprognostic (1.15e-1)" "unprognostic (7.42e-2)" "unprognostic (8.31e-2)" "unprognostic (1.07e-3)" "unprognostic (2.10e-2)" "unprognostic (3.35e-1)" "unprognostic (4.95e-1)" "unprognostic (6.60e-3)" "unprognostic (1.08e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.49e-2)" "unprognostic (6.84e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" 29.0 21.2 17.0 18.5 20.9 42.0 26.0 19.1 23.2 21.1 17.7 23.1 11.8 21.1 17.5 33.0 22.6 12.3 26.1 18.0 18.2 43.8 32.0 22.7 15.1 20.9 19.6 22.1 32.8 16.0 21.5 14.4 20.1 21.9 13.4 15.2 21.3 12.2 24.0 28.9 23.8 13.0 17.0 68.8 25.6 124.2 20.4 41.8 22.0 13.1 15.4 21.2 22.1 26.3 23.1 31.3 28.1 15.4 20.2 25.1 26.9 20.9 20.4 24.7 20.2 25.2 17.0 36.7 16.8 29.6 26.5 50.1 35.2 24.0 32.6 26.4 16.0 25.7 45.7 45.5 18.3 37.4 23.3 20.7 21.9 31.0 27.5 16.9 25.1 23.2 260.6 20.5 28.0 39.4 52.8 41.8 27.7 30.2 27.1 17.8 35.2 36.4 25.0 24.8 21.4 24.8 35.5 30.0 17.3 18.4 41.0 90.3 23.5 44.9 25.2 30.1 31.6 18.8 49.7 39.0 22.3 20.7 28.2 53.2 425.3 174.5 6.7 181.7 8.1 13.5 8.4 6.4 162.2 11.8 6.5 7.5 1259.6 10.2 154.8 16.9 5.2 211.2 17.0 20.9 19.1 23.2 18.0 18.2 20.9 19.6 20.1 17.0 20.4 26.3 24.3 19.2 17.9 46.7 27.8 8.7 11.3 11.4 20.5 31.0 14.7 14.6 21.3 10.0 15.6 23.9 45.9 13.2 31.2 18.6 9.8 10.4 281.4 17.3 20.1 18.6 20.4 20.4 39.7 15.2 11.8 17.8 20.4 18.8 8.8 169.2 21.4 14.5 81.2 16.8 41.1 16.6 22.4 274.8 35.3 404.3 23.3 120.6 10.6 50.6 224.1 14.9 33.0 41.2 75.8 13.8 7.7 20.3 23.4 14.3 15.0 9.1 19.8 32.3 6.6 24.4 36.3 90.8 49.8 16.5 10.9 10.9 22.4 23.0 17.6 11.3 NUP54 ENSG00000138750 "Nucleoporin 54" Q7Z3B4 4 76114659-76148444 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035929, HPA058122" Approved Approved Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA035929: AB_10671236, HPA058122: AB_2683613" "unprognostic (6.70e-2)" "unprognostic (3.51e-2)" "prognostic favorable (8.80e-4)" "unprognostic (3.02e-1)" "unprognostic (3.58e-2)" "unprognostic (4.24e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.51e-3)" "unprognostic (3.05e-2)" "unprognostic (1.62e-1)" "unprognostic (2.49e-3)" "unprognostic (3.36e-2)" "unprognostic (2.10e-2)" "unprognostic (1.22e-1)" "unprognostic (2.01e-1)" "unprognostic (1.83e-1)" "unprognostic (3.65e-3)" 17.5 13.1 6.4 15.8 7.1 35.0 23.4 11.9 9.3 22.4 6.2 19.2 16.5 23.5 18.8 18.1 20.0 15.8 12.2 6.6 7.7 15.2 22.2 16.1 22.1 6.4 6.4 24.3 16.6 15.7 7.5 24.4 6.6 18.5 20.6 12.4 14.7 18.4 12.7 19.3 16.0 20.4 7.1 16.6 16.3 21.8 6.3 28.7 20.6 14.2 24.5 21.7 15.0 9.2 42.6 14.2 52.3 37.1 44.2 40.8 45.0 42.1 61.1 62.1 63.1 36.9 58.4 64.4 34.5 42.3 33.4 27.5 57.0 47.6 76.5 42.5 31.1 38.5 19.1 36.7 41.1 75.8 44.1 37.4 33.6 48.8 50.7 27.1 52.8 41.4 67.1 38.9 44.4 35.9 81.0 39.9 81.3 51.2 14.2 61.6 81.0 25.0 37.3 39.1 31.7 26.6 38.6 45.2 35.4 39.5 18.7 47.2 35.5 48.2 43.0 58.8 52.8 25.1 10.0 60.8 35.1 44.5 44.0 10.1 8.8 9.3 13.3 10.7 18.4 9.7 14.0 13.1 12.9 10.9 14.7 14.1 4.1 26.6 12.6 9.5 14.9 8.5 6.4 7.1 11.9 9.3 6.6 7.7 6.4 6.4 6.6 7.1 6.3 9.2 26.1 22.4 16.7 25.5 31.3 35.2 42.8 29.4 32.5 13.8 18.8 19.3 11.8 14.3 17.8 11.0 20.9 41.3 30.5 13.5 29.4 25.1 12.5 24.9 31.6 23.7 14.4 35.7 42.8 27.7 47.5 26.8 17.3 34.4 24.1 23.0 19.2 13.6 21.7 8.4 42.0 20.8 16.2 16.4 24.2 7.4 27.4 20.2 17.8 18.7 28.6 12.8 35.0 34.2 54.2 19.2 17.1 25.9 30.5 34.1 14.4 20.4 19.2 22.2 32.9 24.8 26.5 46.8 39.9 30.2 29.1 39.1 31.8 21.6 24.4 36.1 NUP58 "KIAA0410, NUP45, NUPL1" ENSG00000139496 "Nucleoporin 58" Q9BVL2 13 25301556-25349800 "Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 122.5;Late spermatids: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039360 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "HPA039360: AB_2676463" "unprognostic (1.13e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (1.13e-2)" "unprognostic (1.94e-2)" "unprognostic (3.35e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (3.56e-4)" "unprognostic (4.85e-2)" "unprognostic (3.79e-2)" "unprognostic (2.40e-1)" "unprognostic (6.14e-2)" "unprognostic (2.04e-2)" "unprognostic (7.19e-3)" "unprognostic (3.02e-3)" "unprognostic (3.03e-1)" "unprognostic (2.47e-2)" "unprognostic (1.06e-1)" 13.2 14.1 11.9 17.2 12.1 34.7 16.1 14.1 14.3 13.6 11.0 12.3 11.8 15.0 12.0 13.7 13.2 13.8 14.1 12.9 13.4 15.5 16.0 19.5 21.5 11.8 13.3 18.4 12.3 10.7 20.9 20.6 11.1 15.4 14.6 27.3 10.7 11.2 20.4 14.2 11.5 14.6 11.1 12.2 13.2 47.6 12.4 26.9 19.5 24.3 18.9 18.7 12.8 14.9 38.5 22.6 53.8 40.6 17.9 25.4 40.9 55.8 41.6 57.9 47.3 37.8 40.5 65.0 26.4 31.6 49.7 41.8 61.6 45.6 92.4 60.5 30.0 90.8 20.8 26.7 33.0 66.5 103.9 17.4 61.8 47.8 106.4 28.6 36.3 55.5 49.4 27.6 66.4 15.2 86.1 47.0 32.4 61.4 19.5 59.1 70.5 29.8 32.1 29.4 63.5 32.0 36.0 27.2 44.6 43.3 18.4 60.6 29.6 37.4 37.2 36.3 66.5 33.9 29.9 87.4 27.6 38.9 65.2 1.4 6.3 1.8 2.4 5.3 3.2 2.4 3.1 2.9 3.8 1.9 3.5 3.1 8.9 2.3 6.3 1.9 4.3 3.4 11.9 12.1 14.1 14.3 12.9 13.4 11.8 13.3 11.1 11.1 12.4 14.9 25.9 41.7 105.2 0.0 53.6 0.0 24.1 0.0 52.3 34.6 27.4 20.7 0.0 20.0 13.6 25.8 54.2 27.2 30.2 8.5 11.7 13.4 122.5 30.6 51.4 23.9 9.7 41.2 0.0 10.9 39.8 27.4 26.0 47.7 24.0 32.9 19.2 27.1 23.0 25.2 0.0 13.7 0.0 40.5 0.0 238.7 19.3 56.6 0.0 0.0 31.7 22.7 19.6 0.0 0.0 19.3 6.8 24.8 41.6 39.7 11.7 37.0 5.8 49.5 19.7 35.8 22.3 86.7 78.8 33.8 0.0 39.5 38.1 21.6 14.0 28.7 NUP62 "DKFZp547L134, FLJ20822, FLJ43869, IBSN, MGC841, p62, SNDI" ENSG00000213024 "Nucleoporin 62" P37198 19 49906825-49929763 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 119.2;Late spermatids: 315.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005435, CAB020724" Supported Supported "Nucleoplasm,Nuclear membrane" NA Yes 31000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" Nucleoplasm "CAB020724: , HPA005435: AB_1079510" "unprognostic (2.26e-1)" "unprognostic (4.06e-2)" "unprognostic (9.92e-2)" "unprognostic (9.68e-2)" "unprognostic (7.83e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.50e-7)" "unprognostic (2.76e-2)" "unprognostic (3.61e-3)" "unprognostic (3.97e-2)" "unprognostic (4.06e-2)" "unprognostic (2.03e-2)" "prognostic unfavorable (5.71e-12)" "unprognostic (3.89e-3)" "unprognostic (3.62e-1)" "unprognostic (3.96e-1)" "unprognostic (3.27e-3)" 19.9 29.4 14.2 37.3 13.2 27.1 18.9 18.4 15.9 22.5 14.0 22.5 23.7 27.6 11.0 25.0 24.8 18.4 20.4 13.9 15.7 18.5 31.7 19.4 38.3 15.5 14.2 29.8 21.0 18.0 22.8 22.4 15.8 19.9 21.1 11.1 21.8 17.5 33.7 23.4 24.3 27.7 13.6 29.8 19.4 50.4 14.7 41.9 16.3 24.5 37.7 24.6 20.1 16.9 126.7 115.5 88.8 74.0 26.0 30.0 79.7 92.8 65.8 99.3 98.8 79.8 71.9 141.2 51.7 60.8 65.9 73.6 108.3 62.1 96.1 211.6 112.0 109.8 59.4 72.6 30.9 108.8 106.8 28.6 44.8 62.0 54.8 44.1 71.5 82.7 138.6 135.5 69.2 59.7 196.7 83.6 82.0 117.4 102.8 170.3 99.9 120.3 46.9 93.7 96.2 68.8 88.2 103.8 46.3 63.8 78.8 51.5 53.0 150.2 85.3 49.1 155.4 96.3 295.9 132.5 62.2 90.1 113.9 12.3 33.4 6.7 17.7 34.7 24.1 15.1 17.6 19.6 33.1 14.9 11.9 15.4 5.2 22.0 20.1 29.0 17.2 22.1 14.2 13.2 18.4 15.9 13.9 15.7 15.5 14.2 15.8 13.6 14.7 16.9 16.8 25.6 22.4 0.0 28.4 34.2 16.5 16.0 21.1 11.4 23.7 26.0 15.4 21.5 18.3 9.2 6.2 37.0 24.4 24.9 9.8 23.7 113.5 19.2 23.9 27.7 21.6 39.1 0.0 16.3 48.4 19.5 20.4 25.6 23.4 30.4 30.4 13.3 49.5 63.9 0.0 27.0 16.2 36.1 119.2 315.1 24.8 41.5 21.4 0.0 77.1 19.1 22.6 0.0 0.0 22.9 22.8 23.0 23.3 24.1 20.6 16.1 19.2 16.3 19.7 18.0 16.0 71.0 39.3 20.0 32.0 21.8 24.4 17.2 33.4 16.6 NUP62CL FLJ20130 ENSG00000198088 "Nucleoporin 62 C-terminal like" Q9H1M0 X 107123427-107206433 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 17.3;fallopian tube: 17.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 21.5;Endometrial ciliated cells: 26.6;Respiratory ciliated cells: 21.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A549: 21.9;CAPAN-2: 23.5;HeLa: 30.7;K-562: 23.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001884 Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA001884: AB_1079512" "unprognostic (1.62e-2)" "prognostic favorable (5.66e-5)" "unprognostic (8.80e-2)" "unprognostic (4.23e-2)" "unprognostic (1.44e-1)" "unprognostic (8.19e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.56e-1)" "unprognostic (5.68e-2)" "unprognostic (1.13e-1)" "unprognostic (2.58e-2)" "unprognostic (6.47e-2)" "unprognostic (1.41e-1)" "unprognostic (1.40e-1)" "unprognostic (2.82e-3)" "unprognostic (4.52e-3)" 0.2 13.9 0.9 1.6 1.0 2.2 3.1 0.7 0.6 1.3 7.6 2.7 3.0 1.8 17.3 1.3 17.2 1.5 1.8 0.8 1.2 6.0 1.9 1.6 1.3 3.6 3.8 1.4 4.3 4.2 2.5 0.4 2.1 0.9 3.3 1.0 2.1 2.9 0.1 1.5 3.0 0.3 2.5 0.2 1.7 12.0 1.2 2.0 10.0 0.5 2.3 0.9 0.9 1.3 13.5 21.9 1.9 0.0 0.0 0.1 9.4 0.0 0.8 0.5 0.5 2.1 23.5 7.7 2.5 0.0 11.9 11.9 13.9 4.8 0.1 0.0 17.8 0.8 30.7 3.9 0.0 0.0 0.0 0.2 6.3 0.1 3.3 0.0 0.0 11.8 23.0 1.9 0.0 6.6 3.0 0.0 2.8 19.1 7.9 0.0 0.0 0.7 7.1 3.6 5.5 6.4 7.8 2.4 0.0 7.8 0.0 0.4 0.0 0.0 7.0 0.1 0.0 2.5 9.4 4.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.2 2.0 0.9 0.0 0.0 1.0 0.4 0.5 0.0 0.7 0.2 0.0 0.4 0.2 0.9 1.0 0.7 0.6 0.8 1.2 3.6 3.8 2.1 2.5 1.2 1.3 0.3 3.2 0.0 0.3 1.7 1.9 3.9 6.3 1.8 0.5 2.8 1.7 1.0 2.8 3.5 9.2 0.0 2.0 0.8 1.7 21.5 2.1 8.8 26.6 0.3 0.4 0.0 3.8 0.4 3.4 1.0 0.2 1.5 4.2 0.0 1.7 0.0 2.2 0.9 1.7 0.5 3.5 6.1 0.0 1.1 3.3 0.3 0.3 5.4 2.8 0.2 1.2 0.0 0.0 0.3 1.4 0.7 0.7 2.4 1.1 1.1 5.7 21.6 0.2 6.6 0.4 0.9 9.6 9.7 1.6 2.8 1.0 1.1 0.0 2.4 2.6 NUP85 "FLJ12549, NUP75" ENSG00000125450 "Nucleoporin 85" Q9BW27 17 75205659-75235758 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061910, HPA062595" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA061910: AB_2684634, HPA062595: AB_2684801" "unprognostic (2.30e-1)" "unprognostic (5.10e-2)" "unprognostic (5.12e-3)" "unprognostic (2.52e-3)" "unprognostic (2.25e-1)" "unprognostic (1.01e-2)" "prognostic unfavorable (1.73e-7)" "unprognostic (3.46e-1)" "unprognostic (1.09e-2)" "unprognostic (9.93e-2)" "unprognostic (2.94e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (1.03e-3)" "unprognostic (2.16e-1)" "unprognostic (9.10e-3)" "unprognostic (2.11e-1)" 20.9 12.9 15.2 18.6 15.7 20.8 20.0 21.8 17.0 21.5 15.4 18.7 15.8 20.8 16.1 20.5 20.9 11.6 16.4 15.6 14.7 18.9 22.1 18.7 26.5 15.8 15.1 20.8 18.7 12.1 12.7 19.0 16.0 18.9 21.0 11.2 16.7 14.3 16.7 23.9 20.5 19.6 14.9 25.3 16.9 22.2 15.3 33.2 18.0 14.1 27.0 17.9 19.5 17.0 66.5 74.0 53.4 37.3 20.3 31.5 74.0 47.3 37.4 108.5 101.7 63.2 61.4 61.1 26.6 41.1 70.5 55.9 88.8 50.6 96.1 19.3 70.1 51.0 83.3 56.3 16.6 52.8 40.7 30.3 30.5 76.1 32.8 24.9 84.7 49.0 63.3 38.1 53.8 73.0 100.2 64.8 40.0 82.2 67.4 68.9 115.1 55.5 42.1 47.5 40.6 38.5 58.2 73.7 42.5 59.4 83.3 59.1 30.8 80.2 74.4 52.5 76.3 23.6 21.0 79.2 41.4 47.3 50.6 8.1 24.9 21.5 16.1 22.6 22.9 16.1 17.5 15.9 20.5 21.5 17.0 12.8 8.2 16.7 16.5 22.5 16.6 17.3 15.2 15.7 21.8 17.0 15.6 14.7 15.8 15.1 16.0 14.9 15.3 17.0 13.2 6.4 12.5 7.2 13.9 6.1 8.9 19.1 6.2 7.8 10.3 7.5 9.0 8.6 15.0 7.3 10.4 23.0 11.7 9.1 7.9 16.0 3.7 11.1 13.6 15.0 7.7 16.2 13.5 19.4 22.1 13.8 9.7 10.3 11.4 13.0 21.0 23.1 23.0 6.7 9.9 11.0 16.2 13.3 7.2 3.9 14.3 13.7 8.8 10.3 15.8 4.8 22.6 3.5 10.6 18.3 7.5 9.8 8.6 7.9 8.8 11.7 11.8 8.8 32.9 7.9 19.2 24.9 29.3 7.3 7.1 12.7 10.9 7.4 13.3 8.0 NUTM2F "DKFZp434I1117, FAM22F" ENSG00000130950 "NUT family member 2F" A1L443 9 94318196-94328644 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 1.9" "Cell type enhanced" "Detected in some" "Astrocytes: 10.4;Excitatory neurons: 42.9;Inhibitory neurons: 29.0;Microglial cells: 11.2;Oligodendrocyte precursor cells: 27.2;Oligodendrocytes: 31.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "NTERA-2: 1.3" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear bodies" "HPA064635: " "unprognostic (1.40e-1)" "unprognostic (4.93e-3)" "unprognostic (4.16e-2)" "unprognostic (1.47e-1)" "unprognostic (9.26e-3)" "unprognostic (1.03e-1)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (6.72e-3)" "unprognostic (8.48e-2)" "unprognostic (1.11e-2)" "unprognostic (5.14e-1)" "unprognostic (1.83e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 27.2 31.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NUTM2G FAM22G ENSG00000188152 "NUT family member 2G" Q5VZR2 9 96928310-96940253 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.2;Oligodendrocyte precursor cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.8;HeLa: 1.7;SiHa: 1.7" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear bodies" "HPA064635: " "unprognostic (2.80e-1)" "unprognostic (2.22e-1)" "unprognostic (9.49e-3)" "unprognostic (7.78e-2)" "unprognostic (1.35e-1)" "unprognostic (2.31e-2)" "unprognostic (2.44e-1)" "unprognostic (1.31e-1)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (2.50e-2)" "unprognostic (1.92e-2)" "unprognostic (3.50e-3)" "unprognostic (2.31e-1)" "unprognostic (3.22e-2)" "unprognostic (2.13e-1)" "unprognostic (4.52e-2)" 0.1 0.2 0.7 0.1 1.0 0.6 0.1 1.3 0.9 0.3 0.2 0.2 0.1 0.2 0.0 0.4 0.1 0.2 0.2 0.8 0.5 0.3 0.1 0.3 0.3 0.8 0.4 0.4 0.3 0.0 0.2 0.1 0.5 0.3 0.0 0.2 0.4 0.0 0.7 0.8 0.2 0.0 0.1 0.3 0.2 2.9 0.8 0.0 0.3 0.0 0.0 0.2 0.3 1.3 0.6 0.5 0.4 0.8 0.0 0.0 0.6 0.2 0.0 0.0 0.0 1.8 0.2 0.6 0.1 0.0 0.5 0.8 0.0 0.0 0.0 0.4 0.7 0.6 1.7 0.8 0.0 0.9 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.9 0.4 0.0 1.0 0.3 0.7 0.9 0.6 0.4 0.4 0.6 0.0 0.0 0.6 0.7 0.2 1.7 0.2 0.1 0.2 0.1 0.0 0.4 0.9 0.3 0.3 0.3 0.2 0.0 0.3 0.1 0.2 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 1.0 1.3 0.9 0.8 0.5 0.8 0.4 0.5 0.1 0.8 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 NXPE1 "FAM55A, MGC34290" ENSG00000095110 "Neurexophilin and PC-esterase domain family member 1" Q8N323 11 114521645-114559895 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "intestine: 79.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 27.0;Early spermatids: 73.6;Intestinal goblet cells: 35.1;Late spermatids: 53.5;Paneth cells: 18.1;Undifferentiated cells: 36.2" "Cancer enriched" "Detected in single" 23 "colorectal cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049133 Enhanced "Intracellular and membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA049133: AB_2680647" "unprognostic (2.81e-1)" "unprognostic (2.19e-3)" "unprognostic (3.40e-3)" "unprognostic (4.10e-1)" "unprognostic (1.05e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (3.40e-2)" "unprognostic (1.76e-1)" 0.0 0.0 0.0 4.9 0.1 0.0 0.1 0.0 0.2 0.0 0.0 64.9 1.2 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.4 0.3 79.7 0.0 1.2 0.0 0.0 0.0 3.5 2.3 0.1 0.0 0.1 4.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.3 0.3 0.1 0.4 0.1 0.2 0.3 0.0 0.0 0.0 2.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 73.6 0.0 0.0 0.0 3.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 35.1 0.0 0.0 0.0 53.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.0 18.1 0.0 0.0 0.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.0 36.2 0.1 NXPE3 "FAM55C, MGC15606" ENSG00000144815 "Neurexophilin and PC-esterase domain family member 3" Q969Y0 3 101779202-101828231 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.2;tongue: 50.5" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 177.7;Plasma cells: 59.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 92.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036259 Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 12000 "Cluster 20: T-cells - T-cell receptor" "Cluster 80: Striated muscle - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "HPA036259: AB_10671838" "unprognostic (3.30e-1)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" "unprognostic (4.42e-5)" "unprognostic (4.98e-2)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (7.42e-2)" "unprognostic (1.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.57e-3)" "unprognostic (3.43e-1)" "prognostic unfavorable (7.76e-6)" "unprognostic (2.89e-1)" "unprognostic (5.23e-2)" "unprognostic (1.77e-1)" "unprognostic (8.75e-3)" 7.8 6.4 13.6 11.7 23.2 12.5 6.0 20.1 18.7 7.6 1.3 5.3 3.5 8.1 3.3 6.1 7.4 6.5 18.4 12.4 21.0 3.3 3.5 9.4 16.7 21.6 21.3 7.1 2.5 20.7 6.8 6.7 24.2 8.3 4.6 11.3 3.5 9.8 73.2 2.0 5.0 10.6 16.5 12.5 5.0 7.4 23.7 13.1 5.9 50.5 14.2 7.2 4.5 34.8 19.8 29.9 25.1 9.2 26.6 26.9 5.7 21.7 27.2 25.4 36.6 7.0 2.0 29.3 62.6 24.4 30.4 4.1 28.3 23.2 31.2 36.7 8.9 22.7 19.0 19.3 35.0 19.4 19.9 15.6 3.9 21.1 7.8 33.1 27.8 27.3 4.7 92.0 42.5 10.6 26.2 4.6 14.6 1.0 18.6 11.5 30.7 12.7 18.8 5.1 19.6 23.4 9.3 2.2 16.7 14.9 4.3 27.2 24.5 28.0 33.7 3.3 23.0 43.0 47.5 34.0 23.9 83.7 5.4 8.0 16.5 20.1 14.6 13.0 10.0 10.8 16.0 15.2 14.2 6.4 21.6 17.6 8.6 8.9 12.7 8.8 20.8 14.1 13.6 23.2 20.1 18.7 12.4 21.0 21.6 21.3 24.2 16.5 23.7 34.8 24.1 25.6 5.1 11.4 19.2 3.7 2.2 2.3 6.2 26.1 9.8 9.0 49.4 4.3 2.3 0.0 8.4 0.7 12.8 1.0 0.0 2.6 1.4 2.9 11.8 17.2 7.2 0.0 34.1 2.6 1.6 10.0 1.5 1.9 13.3 46.0 40.4 1.8 6.8 48.8 35.2 0.6 4.1 19.1 10.0 1.8 9.3 11.0 7.2 9.4 26.3 22.7 23.7 44.2 177.7 2.9 0.1 7.5 59.6 1.0 0.8 0.8 3.1 17.1 19.7 14.9 8.3 11.8 15.1 3.8 3.0 0.7 16.2 20.0 0.9 1.1 NXPE4 "C11orf33, FAM55D, FLJ20127" ENSG00000137634 "Neurexophilin and PC-esterase domain family member 4" Q6UWF7 11 114570591-114595786 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 119.6;salivary gland: 77.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 95.5;Intestinal goblet cells: 88.1;Paneth cells: 41.8;Undifferentiated cells: 115.8" "Cancer enriched" "Detected in some" 15 "colorectal cancer: 13.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042801 Approved "Secreted to digestive system" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA042801: AB_10793986" "unprognostic (1.35e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-3)" "unprognostic (1.27e-1)" "unprognostic (3.51e-3)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (7.47e-3)" "unprognostic (4.36e-2)" "unprognostic (2.05e-1)" 0.1 0.0 0.1 7.8 0.1 0.0 0.4 0.0 0.2 0.0 0.0 114.2 0.6 0.2 6.8 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 5.3 119.6 0.0 77.2 0.2 0.0 0.0 0.7 5.2 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.5 0.0 0.0 0.5 0.0 0.0 0.0 17.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 88.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 41.8 0.0 0.1 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 115.8 0.2 NXPH1 ENSG00000122584 "Neurexophilin 1" P58417 7 8433609-8752961 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "adrenal gland: 42.0;brain: 25.5" "Group enriched" "Detected in some" 40 "Inhibitory neurons: 1486.5;Oligodendrocyte precursor cells: 1500.4" "Group enriched" "Detected in some" 62 "breast cancer: 2.3;glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Karpas-707: 10.9;WM-115: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.84e-2)" "unprognostic (1.30e-1)" "unprognostic (3.74e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-2)" "unprognostic (1.46e-4)" "unprognostic (1.47e-1)" "unprognostic (3.01e-2)" "unprognostic (5.32e-1)" "unprognostic (9.46e-2)" 0.1 42.0 9.6 0.0 11.0 0.0 0.4 4.0 8.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 13.9 0.0 0.0 0.0 0.0 13.4 25.5 0.0 0.0 0.0 1.5 0.0 12.1 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 24.9 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 11.0 4.0 8.7 8.6 13.9 13.4 25.5 12.1 6.3 24.9 5.5 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1486.5 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 36.5 0.0 0.6 0.0 1500.4 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.1 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NXPH2 NPH2 ENSG00000144227 "Neurexophilin 2" O95156 2 138669157-138780390 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.1;kidney: 4.1;ovary: 8.1" "Cell type enriched" "Detected in some" 6 "Inhibitory neurons: 156.1" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 6 "medulla oblongata: 11.7;midbrain: 7.6;pons: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.4;SiHa: 3.0;SuSa: 2.1;U-2 OS: 4.7;U-251 MG: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034759 Approved "Secreted in brain" NA Yes "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034759: AB_10669732" "unprognostic (5.83e-2)" "unprognostic (8.83e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-1)" "unprognostic (1.80e-1)" 0.2 0.0 1.8 0.1 1.7 0.0 0.1 1.0 1.8 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.0 0.4 4.1 0.0 0.0 0.0 11.7 7.6 8.1 0.0 0.0 0.1 0.1 13.1 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.6 3.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 4.7 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.7 1.0 1.8 1.0 0.4 11.7 7.6 13.1 1.9 1.1 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 156.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NXPH3 NPH3 ENSG00000182575 "Neurexophilin 3" O95157 17 49575871-49583827 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.4" "Cell type enhanced" "Detected in some" "Astrocytes: 14.0;Bipolar cells: 23.3;Fibroblasts: 7.6;Muller glia cells: 8.5;Peritubular cells: 14.3;Smooth muscle cells: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 11.4;BJ: 3.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 41.1" HPA073819 Approved "Vesicles,Mitotic spindle" "Secreted in brain" Yes NA "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Mitotic spindle" "HPA073819: " "unprognostic (2.39e-2)" "unprognostic (4.75e-2)" "unprognostic (2.33e-2)" "unprognostic (3.34e-1)" "unprognostic (1.92e-1)" "unprognostic (3.30e-1)" "unprognostic (1.97e-1)" "unprognostic (8.01e-2)" "unprognostic (4.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-2)" "unprognostic (6.33e-2)" "unprognostic (4.62e-4)" "unprognostic (2.59e-2)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (5.05e-3)" 3.9 0.9 1.8 1.0 1.8 0.0 2.9 16.4 3.5 9.0 0.7 11.0 0.4 12.0 0.6 1.5 7.0 1.7 2.9 3.5 0.5 0.4 0.1 2.7 0.5 6.3 3.8 5.2 0.6 1.3 7.5 1.3 6.4 5.9 0.3 0.6 3.1 4.7 1.2 2.3 1.7 2.5 0.1 1.0 3.4 1.6 3.9 0.3 1.4 2.0 0.3 8.9 6.9 3.0 0.0 0.0 0.1 0.0 0.0 0.2 11.4 3.2 0.4 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.6 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 16.4 3.5 3.5 0.5 6.3 3.8 6.4 0.1 3.9 3.0 0.5 0.0 1.3 14.0 0.0 0.4 0.3 0.2 0.6 23.3 0.9 0.5 1.7 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.8 1.6 0.0 0.0 2.5 0.2 3.2 7.6 0.0 0.5 0.0 0.0 6.4 0.0 0.2 0.0 1.5 0.0 0.0 0.3 1.4 0.0 4.4 0.3 1.8 0.0 4.2 8.5 0.0 2.5 0.5 0.0 0.0 14.3 0.7 0.3 0.0 0.0 0.0 1.2 0.0 0.8 8.9 0.1 1.3 0.0 1.1 0.1 0.2 0.1 0.0 0.1 NXPH4 NPH4 ENSG00000182379 "Neurexophilin 4" O95158 12 57216794-57226449 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4;skin 1: 19.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 14.5;Cytotrophoblasts: 29.0;Muller glia cells: 18.5;Suprabasal keratinocytes: 10.4;Syncytiotrophoblasts: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 76.8;RH-30: 62.3;RPMI-8226: 43.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted in brain" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.08e-2)" "unprognostic (4.84e-2)" "unprognostic (2.70e-3)" "prognostic unfavorable (6.21e-4)" "prognostic unfavorable (5.42e-4)" "unprognostic (1.16e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (3.07e-1)" "unprognostic (1.51e-2)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (6.77e-2)" "prognostic unfavorable (7.68e-6)" "unprognostic (7.83e-2)" "unprognostic (2.73e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-3)" 2.5 0.6 6.3 0.3 4.1 0.4 0.7 8.3 3.6 2.3 0.6 0.1 0.0 0.0 0.2 3.0 0.1 0.0 2.7 8.3 13.8 0.7 0.8 0.3 0.5 13.3 7.1 0.0 1.5 1.7 0.3 2.7 18.4 4.4 0.0 5.0 4.0 0.0 0.2 19.4 0.2 0.1 7.5 0.4 0.1 1.2 7.1 0.1 0.4 0.0 0.3 0.1 2.8 5.0 18.1 1.4 0.4 76.8 8.6 2.2 7.1 4.9 11.5 2.1 2.7 5.0 0.9 19.4 7.6 5.1 3.2 16.2 10.3 2.4 0.6 3.4 20.6 0.1 0.6 0.3 7.4 0.7 2.5 2.0 4.0 2.0 3.2 2.5 0.0 1.2 0.8 20.0 1.5 18.6 0.0 0.0 0.7 0.4 13.5 1.0 62.3 43.1 0.0 3.2 12.3 0.7 11.0 22.5 23.2 0.2 22.4 0.6 0.0 5.4 17.8 2.3 5.8 10.8 2.3 6.9 3.5 9.6 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 4.1 8.3 3.6 8.3 13.8 13.3 7.1 18.4 7.5 7.1 5.0 0.8 0.0 0.0 0.7 8.0 14.5 0.4 1.1 3.4 4.7 0.7 0.9 0.8 0.0 0.7 0.0 8.4 29.0 0.3 0.1 0.0 0.8 0.0 0.1 0.4 0.5 7.2 0.0 0.7 0.0 1.9 1.1 0.5 0.1 0.0 1.1 0.0 0.1 2.0 1.7 1.4 0.0 2.0 0.0 0.8 0.0 0.0 0.4 3.6 0.0 0.0 18.5 0.0 0.0 0.1 0.6 0.0 0.4 0.3 3.3 0.0 0.0 1.0 0.5 0.0 2.4 3.6 0.7 4.5 1.8 10.4 29.3 0.4 0.0 0.0 0.4 NYX "CLRP, CSNB1, CSNB1A, CSNB4" ENSG00000188937 Nyctalopin Q9GZU5 X 41447343-41475710 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 7 "Bipolar cells: 13.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "HDLM-2: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (3.27e-2)" "unprognostic (6.72e-2)" "unprognostic (4.21e-2)" "unprognostic (4.10e-4)" "unprognostic (1.83e-1)" "unprognostic (3.96e-2)" "unprognostic (1.80e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 0.5 1.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 396.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.9;Fibroblasts: 135.9;Hepatocytes: 218.8;Muller glia cells: 279.4;Theca cells: 149.0;Urothelial cells: 192.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 115.5;Hep G2: 190.1;NB-4: 139.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA047412: AB_10960631" "unprognostic (1.59e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.11e-1)" "unprognostic (3.98e-3)" "unprognostic (5.09e-2)" "unprognostic (3.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.12e-2)" "unprognostic (7.15e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" 66.0 91.5 47.7 18.0 56.8 10.8 42.6 35.8 57.1 66.7 40.5 61.9 47.7 54.2 16.0 22.8 54.6 34.5 55.1 48.1 36.5 51.4 396.6 19.2 5.8 39.0 37.8 61.0 74.1 6.7 27.4 8.1 37.1 33.5 36.5 30.7 53.9 13.7 13.2 12.0 57.3 29.1 35.9 54.4 33.5 3.7 45.0 4.6 25.9 12.2 3.7 42.6 40.4 44.6 24.9 7.5 30.9 14.4 47.8 53.4 1.7 47.7 53.8 20.5 30.0 7.5 37.3 0.0 115.5 35.6 33.7 25.7 8.9 13.2 8.2 18.7 21.1 21.1 4.7 190.1 42.4 46.7 7.9 66.8 7.9 19.8 54.8 39.9 59.7 12.7 14.0 22.7 5.0 9.4 0.3 139.9 11.6 7.3 40.8 11.8 0.9 23.7 31.8 13.4 1.5 10.0 14.0 15.2 40.2 8.6 4.8 74.7 32.7 39.3 14.7 40.8 4.6 0.8 0.7 0.4 30.3 76.2 14.1 0.0 3.3 0.0 0.1 1.6 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.2 0.1 0.0 0.3 0.5 0.1 0.8 47.7 56.8 35.8 57.1 48.1 36.5 39.0 37.8 37.1 35.9 45.0 44.6 19.4 0.0 0.6 102.2 3.7 9.4 33.6 7.3 12.5 3.2 6.0 7.0 5.5 34.3 3.5 71.7 2.1 2.1 1.1 135.9 27.4 14.8 0.2 4.7 70.9 40.0 22.8 12.8 0.6 28.7 5.5 135.9 11.7 12.2 1.3 2.6 12.5 218.8 6.0 0.0 2.3 56.5 4.1 11.5 20.9 1.1 16.8 11.0 16.0 23.4 10.2 279.4 0.0 5.5 11.0 28.2 56.5 4.5 14.5 31.3 111.1 79.3 0.4 10.6 52.6 8.6 40.8 0.7 6.9 11.3 10.2 6.2 3.1 149.0 45.8 192.5 OBP2A "hOBPIIa, LCN13, OBP" ENSG00000122136 "Odorant binding protein 2A" Q9NY56 9 135546126-135549969 "Predicted secreted proteins" "Olfaction, Sensory transduction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "fallopian tube: 24.9" "Cell type enhanced" "Detected in some" "Breast glandular cells: 2.4;Breast myoepithelial cells: 3.4;Late spermatids: 1.8;Leydig cells: 1.5;Melanocytes: 1.8" "Cancer enriched" "Detected in some" 6 "ovarian cancer: 18.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "U-266/70: 1.6;U-266/84: 6.4" HPA055955 Uncertain "Secreted in other tissues" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 16: U-266 - Nucleosome" "Cluster 44: Endometrium - Transcription" "HPA055955: AB_2682985" "unprognostic (2.30e-1)" "unprognostic (3.68e-1)" "unprognostic (4.63e-1)" "unprognostic (1.66e-2)" "unprognostic (2.17e-1)" "unprognostic (3.20e-1)" "unprognostic (2.75e-1)" "unprognostic (7.65e-2)" "unprognostic (2.23e-2)" "unprognostic (8.27e-2)" "unprognostic (1.91e-1)" "unprognostic (6.83e-11)" "unprognostic (5.17e-2)" "unprognostic (3.61e-1)" "unprognostic (1.26e-1)" "unprognostic (3.84e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.9 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.5 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 OBP2B "hOBPIIb, LCN14" ENSG00000171102 "Odorant binding protein 2B" Q9NPH6 9 133205277-133209250 "Predicted secreted proteins" "Olfaction, Sensory transduction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 2.7;testis: 10.0" "Group enriched" "Detected in some" 9 "Breast glandular cells: 17.7;Breast myoepithelial cells: 29.1" "Group enriched" "Detected in many" 8 "breast cancer: 7.8;endometrial cancer: 16.2;ovarian cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.40e-1)" "unprognostic (5.70e-2)" "unprognostic (9.45e-3)" "unprognostic (6.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.30e-1)" "unprognostic (7.03e-2)" "unprognostic (6.82e-6)" "unprognostic (2.00e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.4 0.3 0.0 0.0 0.0 17.7 29.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 2.5 1.2 0.1 1.8 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.2 1.2 0.1 0.1 OC90 PLA2L ENSG00000253117 "Otoconin 90" Q02509 8 132024216-132059382 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.92e-1)" "unprognostic (2.93e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OCEL1 FLJ22709 ENSG00000099330 "Occludin/ELL domain containing 1" Q9H607 19 17226213-17229219 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "liver: 75.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 137.0;Proximal tubular cells: 150.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 34.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042070, HPA043223" Uncertain Approved "Golgi apparatus" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA042070: AB_2677830, HPA043223: " "unprognostic (6.34e-2)" "unprognostic (6.28e-2)" "unprognostic (3.13e-1)" "unprognostic (3.00e-3)" "unprognostic (6.40e-2)" "unprognostic (2.06e-2)" "unprognostic (4.33e-3)" "unprognostic (2.02e-1)" "unprognostic (1.16e-1)" "unprognostic (1.67e-1)" "unprognostic (7.73e-2)" "unprognostic (4.64e-1)" "unprognostic (1.34e-1)" "unprognostic (2.52e-1)" "unprognostic (2.88e-1)" "unprognostic (9.19e-2)" "unprognostic (1.18e-3)" 18.3 21.6 14.9 4.7 15.8 5.6 16.4 15.9 24.9 14.8 15.5 20.9 19.0 13.5 18.9 9.4 18.1 5.8 17.4 14.6 15.6 37.4 75.5 14.6 7.3 17.4 16.0 11.2 22.7 7.2 9.2 6.7 17.0 21.1 12.3 8.9 14.9 9.0 14.0 8.8 20.0 7.2 16.4 17.3 22.1 6.7 16.5 6.7 20.5 13.5 9.5 13.9 12.3 15.8 8.2 6.4 3.3 2.9 34.9 13.8 8.5 5.3 14.5 4.1 7.2 4.6 9.8 7.2 19.5 7.8 3.6 3.9 4.5 5.4 3.8 6.0 5.3 6.7 6.8 22.6 11.7 1.4 10.5 11.1 5.6 4.8 8.1 14.2 5.9 8.9 5.8 6.8 7.5 6.7 3.7 4.0 5.6 12.3 11.3 2.7 2.8 18.2 17.7 11.2 1.1 5.6 3.3 10.8 9.4 6.9 16.4 6.8 3.9 2.6 3.0 5.1 2.6 18.5 15.3 5.8 7.7 6.3 1.2 27.7 30.8 15.2 9.9 20.9 9.5 15.7 15.1 11.4 23.3 17.0 16.5 10.8 9.7 16.0 17.1 10.0 19.1 13.4 14.9 15.8 15.9 24.9 14.6 15.6 17.4 16.0 17.0 16.4 16.5 15.8 14.6 12.8 8.2 3.9 16.4 6.4 26.7 18.8 17.1 11.4 21.4 23.7 7.3 27.1 21.9 20.2 2.1 38.6 23.9 66.8 60.7 21.4 6.3 59.3 12.5 15.6 17.4 9.7 4.7 27.1 46.0 17.2 25.5 20.4 15.9 8.0 25.0 93.5 25.8 25.2 5.2 40.5 10.2 26.1 7.5 14.6 28.3 22.3 16.0 3.7 19.2 29.6 24.7 1.0 4.6 21.0 67.4 23.3 23.2 20.7 137.0 150.5 71.8 9.7 32.9 12.5 25.8 7.8 13.8 8.8 6.7 103.2 16.4 19.9 28.1 21.9 OCIAD1 "Asrij, FLJ20455, OCIA, TPA018" ENSG00000109180 "OCIA domain containing 1" Q9NX40 4 48805212-48861817 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044803 Approved Approved Mitochondria NA NA 21000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA044803: AB_10961287" "unprognostic (8.18e-2)" "unprognostic (1.60e-2)" "unprognostic (4.82e-2)" "unprognostic (7.39e-2)" "unprognostic (1.69e-1)" "unprognostic (4.17e-2)" "unprognostic (2.53e-1)" "unprognostic (1.60e-1)" "unprognostic (4.10e-1)" "unprognostic (2.83e-3)" "unprognostic (1.34e-1)" "unprognostic (5.42e-2)" "unprognostic (1.47e-3)" "unprognostic (9.23e-2)" "unprognostic (2.86e-1)" "unprognostic (1.56e-1)" "unprognostic (1.16e-2)" 129.5 184.0 161.1 99.4 170.6 107.7 153.9 154.6 212.9 150.3 173.5 161.1 155.8 138.0 192.2 118.1 167.2 124.6 219.3 177.3 177.0 238.1 326.5 124.1 127.3 161.1 153.1 159.1 156.1 248.7 109.9 118.4 157.6 145.9 159.9 143.7 161.9 148.1 255.0 107.1 134.6 133.3 163.1 105.1 141.3 91.0 165.8 133.6 239.4 255.9 133.9 136.3 72.3 172.6 165.2 118.2 231.7 162.8 230.8 283.0 178.6 253.1 393.8 261.1 311.3 110.6 473.2 190.4 241.5 238.0 311.4 141.7 229.4 250.4 296.2 149.4 152.7 293.4 105.7 88.1 336.5 309.1 300.9 292.0 353.5 208.3 258.4 315.4 270.0 173.9 339.8 104.1 300.0 107.7 261.4 287.6 195.2 211.7 110.4 169.6 216.9 203.1 502.9 154.5 139.8 261.0 120.4 101.1 306.5 179.8 212.8 271.5 196.9 176.1 200.7 120.7 333.1 256.3 380.4 283.1 223.2 251.0 220.2 47.8 60.2 76.5 62.6 68.0 90.8 74.1 73.1 79.2 75.4 64.9 90.2 80.5 48.3 95.4 86.5 85.2 68.5 73.5 161.1 170.6 154.6 212.9 177.3 177.0 161.1 153.1 157.6 163.1 165.8 172.6 176.7 160.3 124.5 85.8 107.1 79.7 111.3 243.3 102.4 126.6 96.7 119.6 152.3 102.9 169.4 121.4 66.7 170.5 103.1 140.0 137.0 140.0 34.3 147.3 120.5 120.2 130.1 89.8 125.1 128.3 168.8 124.4 84.1 110.5 141.8 102.6 118.9 167.3 152.7 89.2 137.2 131.3 124.1 94.0 77.2 35.5 132.3 106.1 87.2 76.8 107.2 206.1 121.5 106.1 158.1 130.7 122.5 139.2 115.3 104.2 164.1 178.9 151.2 111.6 124.9 121.3 112.7 188.3 88.3 94.1 75.9 164.7 109.8 197.2 142.7 100.4 ODAM "APin, FLJ20513" ENSG00000109205 "Odontogenic, ameloblast associated" A1E959 4 70196496-70204576 "Cancer-related genes, Predicted intracellular proteins" Biomineralization "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "salivary gland: 371.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 4.2;Breast glandular cells: 10.3;Ductal cells: 6.5;Exocrine glandular cells: 8.2;Gastric mucus-secreting cells: 6.6;Glandular and luminal cells: 10.5;Theca cells: 4.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "Hep G2: 31.7;OE19: 21.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA036279, HPA036543, HPA070297" Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm Cytosol "HPA036279: , HPA036543: AB_10669797, HPA070297: " "unprognostic (2.34e-2)" "unprognostic (2.43e-1)" "unprognostic (1.26e-1)" "unprognostic (1.75e-1)" "unprognostic (3.34e-3)" "unprognostic (1.06e-1)" "unprognostic (1.88e-2)" "unprognostic (3.47e-1)" "unprognostic (3.08e-1)" "unprognostic (3.03e-1)" "unprognostic (2.72e-1)" "unprognostic (1.86e-2)" "unprognostic (2.50e-2)" 0.0 0.8 0.0 2.9 0.0 0.0 0.7 0.0 0.0 0.3 0.1 3.6 1.0 0.1 0.6 0.2 0.1 0.5 0.0 0.0 0.8 1.2 0.0 2.4 0.3 1.2 0.7 0.0 0.5 3.6 0.5 0.3 0.0 1.8 0.8 0.0 371.5 1.4 0.0 0.0 0.7 7.3 0.0 0.0 9.8 0.0 0.2 0.0 4.1 0.0 1.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.7 0.0 0.0 0.2 0.0 0.1 3.2 4.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 10.3 0.4 0.0 1.5 1.3 1.8 0.0 0.4 0.0 0.0 0.0 6.5 0.0 2.3 0.9 0.1 0.0 0.0 0.0 8.2 0.0 0.0 6.6 10.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 4.2 0.5 0.4 ODAPH "AI2A4, C4orf26, FLJ23657" ENSG00000174792 "Odontogenesis associated phosphoprotein" Q17RF5 4 75556048-75565871 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 1.7;placenta: 5.8" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 9.2;Syncytiotrophoblasts: 27.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.1;urothelial cancer: 0.7" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 33 "basophil: 10.7" "Lineage enriched" "Detected in single" 33 "granulocytes: 10.7" "Cell line enriched" "Detected in some" 6 "HDLM-2: 61.3" "Secreted in other tissues" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.13e-1)" "unprognostic (4.45e-3)" "unprognostic (3.78e-1)" "unprognostic (1.66e-1)" "unprognostic (6.12e-2)" "unprognostic (2.12e-2)" "unprognostic (1.75e-2)" "unprognostic (2.44e-1)" "unprognostic (3.87e-2)" "unprognostic (5.30e-2)" "unprognostic (3.43e-1)" "unprognostic (1.17e-7)" "unprognostic (8.31e-2)" "unprognostic (2.70e-2)" "unprognostic (8.40e-4)" "unprognostic (6.53e-3)" 0.1 0.1 0.7 0.2 0.7 0.3 0.1 0.9 1.7 0.1 0.5 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.6 0.1 0.1 0.1 0.2 0.8 0.8 0.1 0.0 0.0 0.4 5.8 0.9 0.1 0.2 0.5 0.1 0.1 0.9 0.3 0.2 0.0 0.6 0.1 0.1 0.4 0.7 0.1 0.0 0.0 0.3 0.1 0.1 1.5 0.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 1.3 0.5 0.1 0.2 0.0 0.1 0.1 0.0 0.2 0.3 61.3 0.0 0.2 0.2 0.3 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.7 0.1 0.0 0.1 0.0 2.8 0.0 2.1 0.3 0.1 0.0 0.1 2.6 0.1 0.9 9.6 0.1 0.1 0.6 0.2 0.0 10.7 0.1 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 0.7 0.7 0.9 1.7 0.6 0.6 0.8 0.8 0.9 0.6 0.7 1.5 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 1.8 0.0 1.9 0.1 0.0 0.0 3.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 9.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 27.0 0.1 0.1 0.0 0.0 OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.0" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 104.1;Fibroblasts: 326.2;Leydig cells: 166.2;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Group enriched" "Detected in some" 4 "ASC TERT1: 22.2;HSkMC: 9.7;JURKAT: 15.7;MOLT-4: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 170000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" 100.1 22.5 1.4 6.0 3.0 0.2 53.8 4.7 6.8 216.0 11.0 43.0 10.6 130.5 44.9 30.8 67.1 164.7 79.8 1.7 2.3 6.4 4.1 18.6 2.1 1.8 1.8 91.8 11.1 117.3 19.1 22.7 2.0 57.9 32.2 0.0 3.2 19.3 2.6 3.8 23.6 118.0 2.3 2.4 22.0 13.3 2.2 4.5 14.7 22.0 5.6 54.0 23.3 2.1 0.0 0.0 0.0 0.0 4.4 22.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 9.7 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.1 32.2 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 1.4 3.0 4.7 6.8 1.7 2.3 1.8 1.8 2.0 2.3 2.2 2.1 10.3 6.4 1.5 1.0 0.4 4.2 0.1 0.0 1.2 0.6 0.7 0.4 2.6 10.0 7.4 3.7 0.0 2.0 0.6 0.1 0.0 0.0 1.2 2.9 104.1 5.2 0.0 0.0 1.9 0.0 1.7 326.2 7.7 1.7 1.3 0.0 20.0 0.1 4.6 0.0 1.8 0.0 0.0 0.3 11.1 4.2 166.2 2.3 1.8 16.9 0.2 0.1 0.0 2.0 1.6 0.0 0.0 212.1 0.7 0.4 0.0 0.0 2.9 0.2 6.6 4.7 22.7 0.6 0.6 0.7 4.5 5.7 2.1 1.6 0.0 0.2 OIT3 "FLJ39116, LZP" ENSG00000138315 "Oncoprotein induced transcript 3" Q8WWZ8 10 72893584-72933036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 110.8" "Cell type enriched" "Detected in some" 11 "Hepatic stellate cells: 372.3" "Cancer enriched" "Detected in many" 4 "liver cancer: 4.6" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 2.3;Hep G2: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 52000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.42e-2)" "unprognostic (6.76e-2)" "unprognostic (7.98e-4)" "unprognostic (9.26e-2)" "unprognostic (9.47e-4)" "unprognostic (3.05e-1)" "unprognostic (4.33e-2)" "unprognostic (1.99e-2)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (8.50e-3)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" "unprognostic (1.35e-1)" "unprognostic (2.44e-1)" "unprognostic (3.68e-3)" "unprognostic (1.19e-1)" 0.0 0.0 0.1 0.3 0.1 0.0 0.0 1.3 0.5 0.0 0.1 0.3 5.3 0.0 0.0 0.0 0.0 0.3 2.8 0.1 0.0 1.5 110.8 0.3 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 6.1 0.0 0.0 7.8 0.1 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.3 0.5 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 10.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.0 14.6 0.0 10.7 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 372.3 10.6 0.0 0.0 0.9 0.0 0.0 31.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.4 0.5 0.0 0.0 OLFM1 "AMY, NOE1, NOELIN, OlfA" ENSG00000130558 "Olfactomedin 1" Q99784 9 135075422-135121180 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 555.7;choroid plexus: 246.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 193.1;Hepatic stellate cells: 78.1;Inhibitory neurons: 70.0" "Cancer enhanced" "Detected in all" "glioma: 18.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;intermediate monocyte: 2.8;myeloid DC: 2.6" "Group enriched" "Detected in many" 27 "dendritic cells: 2.6;monocytes: 2.8" "Cell line enhanced" "Detected in many" "HeLa: 96.0;MCF7: 84.1;NTERA-2: 104.9;OE19: 78.9;SCLC-21H: 155.6;SiHa: 131.8;T-47d: 200.2;U-2197: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057444 Approved Nucleoplasm,Nucleoli,Cytosol "Secreted in brain" NA NA 200000000 "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Nucleoplasm, Cytosol" "HPA057444: AB_2683443" "unprognostic (6.77e-2)" "prognostic favorable (7.14e-4)" "unprognostic (1.01e-1)" "unprognostic (3.76e-2)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.08e-1)" "unprognostic (1.30e-1)" "unprognostic (3.69e-3)" "unprognostic (2.67e-1)" "unprognostic (6.04e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (9.46e-3)" "unprognostic (4.60e-2)" "unprognostic (1.51e-1)" "unprognostic (6.20e-2)" "unprognostic (7.53e-4)" 36.7 25.4 410.4 13.0 427.0 0.2 36.8 309.6 555.7 29.9 246.9 24.0 5.0 29.0 70.4 12.1 30.3 8.6 20.7 474.7 309.0 20.3 4.8 15.0 14.5 296.6 301.7 19.4 12.3 4.9 82.8 1.0 293.9 19.3 13.8 47.3 14.0 18.1 17.5 15.3 16.5 17.9 279.9 35.1 15.4 6.8 317.0 11.5 17.5 23.0 19.1 25.0 26.7 372.3 0.0 6.1 12.1 0.2 1.7 1.4 0.5 3.6 0.0 0.0 0.0 0.1 2.7 0.1 0.8 5.2 49.2 2.3 2.6 0.0 0.0 14.4 0.9 0.2 96.0 0.0 0.5 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.3 84.1 0.5 0.3 104.9 78.9 0.0 0.1 0.3 48.3 0.0 0.1 155.6 20.5 131.8 0.4 8.6 7.9 200.2 0.0 0.1 7.7 16.6 87.1 0.2 0.2 0.1 0.3 0.7 0.1 4.3 0.0 1.8 0.0 0.0 2.8 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 410.4 427.0 309.6 555.7 474.7 309.0 296.6 301.7 293.9 279.9 317.0 372.3 44.2 0.0 7.9 43.8 0.1 9.7 3.3 0.0 3.4 21.6 3.1 3.0 5.9 11.5 1.8 0.0 43.8 0.0 0.1 2.4 0.0 9.7 5.8 0.5 20.4 50.0 2.4 0.0 193.1 2.7 0.0 17.3 0.0 0.7 2.5 14.4 78.1 1.1 0.4 38.7 70.0 2.5 0.0 3.2 7.3 11.9 44.4 2.8 21.4 32.8 2.7 38.6 0.0 48.7 17.3 2.5 2.5 29.3 0.4 5.1 0.0 0.1 0.0 15.7 0.0 13.3 8.8 0.6 3.7 1.3 6.3 0.0 0.7 12.9 4.2 1.4 OLFM2 "NOE2, OlfC" ENSG00000105088 "Olfactomedin 2" O95897 19 9853718-9936552 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 202.6;skin 1: 94.8" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Basal keratinocytes: 125.0;Muller glia cells: 91.1;Oligodendrocyte precursor cells: 124.7;Suprabasal keratinocytes: 118.1" "Cancer enhanced" "Detected in all" "glioma: 96.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.7" "Group enriched" "Detected in many" 26 "granulocytes: 49.7;T-cells: 17.0" "Cell line enhanced" "Detected in many" "AN3-CA: 25.6;ASC diff: 23.4;BJ hTERT+: 18.5;SH-SY5Y: 24.3;U-2 OS: 28.7;WM-115: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049961, HPA057771" Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA 2700000 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA049961: AB_2680972, HPA057771: AB_2683524" "unprognostic (1.42e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.99e-2)" "unprognostic (5.91e-2)" "unprognostic (3.39e-2)" "unprognostic (8.78e-2)" "unprognostic (4.47e-2)" "unprognostic (8.04e-2)" "unprognostic (4.03e-2)" "unprognostic (1.41e-3)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.23e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" 36.8 30.7 130.8 3.4 134.5 0.2 25.0 118.5 202.6 17.2 80.7 4.8 2.1 16.7 4.5 5.6 11.1 6.7 10.1 134.0 127.3 9.2 41.9 10.1 7.9 152.5 168.8 9.7 11.2 9.6 19.1 7.1 162.0 10.1 1.1 24.6 10.0 13.4 1.8 94.8 3.8 6.7 130.0 2.5 2.2 10.7 123.2 16.5 13.2 1.0 4.8 3.0 14.1 120.7 0.0 3.7 3.0 25.6 23.4 14.3 1.7 5.6 18.5 1.2 1.5 0.3 2.4 0.1 2.3 4.2 2.1 1.5 9.8 1.7 0.1 0.1 2.1 0.0 0.2 0.3 0.1 0.0 4.3 7.5 1.5 0.1 0.2 0.7 0.1 4.8 0.3 0.3 0.0 8.2 0.3 0.2 15.8 2.5 0.0 0.1 0.0 0.0 0.0 0.9 0.1 24.3 0.9 0.1 5.2 9.7 0.9 0.0 0.3 10.5 28.7 0.1 0.1 0.0 0.0 0.0 0.3 0.0 25.6 21.2 0.0 49.7 6.2 0.0 6.6 0.0 7.0 5.5 0.0 0.0 13.5 8.9 0.5 1.2 0.0 0.1 17.0 2.9 130.8 134.5 118.5 202.6 134.0 127.3 152.5 168.8 162.0 130.0 123.2 120.7 12.9 0.0 0.0 108.4 0.3 125.0 4.7 5.9 8.6 4.9 6.9 13.8 0.8 7.2 0.4 7.3 0.0 0.1 1.0 0.1 1.9 0.9 8.6 0.9 2.2 4.3 1.2 0.4 27.3 2.4 0.0 17.2 0.0 1.0 4.5 6.5 1.4 24.7 0.3 1.7 51.0 0.2 2.0 0.3 32.6 52.8 13.7 0.6 17.8 15.0 0.4 91.1 7.2 124.7 3.5 4.1 0.0 9.8 0.5 7.9 0.0 0.2 0.2 3.7 0.0 7.4 24.3 3.0 10.4 1.4 118.1 0.1 7.7 0.6 0.1 2.9 OLFM3 NOE3 ENSG00000118733 "Olfactomedin 3" Q96PB7 1 101802560-101996926 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 12.0;retina: 7.4" "Group enriched" "Detected in some" 17 "Excitatory neurons: 653.3;Inhibitory neurons: 174.6" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "AF22: 5.7;HAP1: 3.9;HEL: 3.6;SCLC-21H: 2.2;SH-SY5Y: 2.2" "Region enhanced" "Detected in all" "cerebellum: 177.3" "Low region specificity" "Detected in all" HPA050297 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA050297: " "unprognostic (4.19e-1)" "unprognostic (4.19e-4)" "unprognostic (1.26e-1)" "unprognostic (4.61e-2)" "unprognostic (2.93e-1)" "unprognostic (1.47e-2)" "unprognostic (3.58e-4)" "unprognostic (2.48e-1)" "unprognostic (5.68e-2)" 0.0 1.3 2.9 0.3 5.0 0.0 0.0 6.9 12.0 0.0 0.0 0.6 0.2 0.1 0.2 0.0 0.0 0.0 0.0 6.4 3.9 0.4 0.0 0.0 0.0 1.2 1.9 0.0 0.0 0.0 1.2 0.0 1.2 0.0 0.5 7.4 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.2 0.1 3.7 0.0 0.3 0.0 0.0 0.0 0.0 4.6 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 2.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 5.0 6.9 12.0 6.4 3.9 1.2 1.9 1.2 0.0 3.7 4.6 0.1 0.0 0.0 10.7 0.0 0.0 0.1 0.0 0.0 23.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 653.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 174.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 0.7 0.0 8.5 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 6.5 0.0 0.0 OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1296.1;pancreas: 671.4" "Cell type enhanced" "Detected in many" "Ductal cells: 497.1;Exocrine glandular cells: 900.9;Intestinal goblet cells: 791.9;Pancreatic endocrine cells: 933.7;Paneth cells: 556.9;Undifferentiated cells: 2419.9;Urothelial cells: 1989.0" "Group enriched" "Detected in many" 14 "colorectal cancer: 711.4;pancreatic cancer: 594.7;stomach cancer: 724.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 5.4;BJ hTERT+: 18.8;HaCaT: 26.4;OE19: 10.4;RPMI-8226: 6.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" Yes NA 9300 "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: AB_2732358" "prognostic favorable (8.77e-4)" "unprognostic (4.84e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" "unprognostic (7.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-1)" "unprognostic (4.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-2)" "unprognostic (4.84e-3)" 1.9 0.1 0.2 195.4 0.5 126.0 6.8 0.1 0.5 7.9 0.2 451.6 1211.9 5.5 3.5 0.8 8.3 10.4 0.8 0.2 0.4 26.9 0.9 3.8 1.4 0.1 0.2 0.2 671.4 0.0 0.5 0.6 0.2 92.4 568.7 0.4 16.2 0.9 0.6 0.4 1296.1 52.6 0.2 18.0 16.1 0.3 0.2 4.2 0.4 2.1 0.2 127.0 285.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.4 2.4 18.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 26.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 10.4 0.0 0.0 0.8 6.2 0.2 0.0 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.6 0.9 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.5 0.2 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.3 3.8 0.1 168.5 0.3 0.0 0.0 9.8 2.5 0.5 0.0 11.9 139.8 0.0 0.0 0.0 98.7 1.9 497.1 0.2 13.5 0.5 1.4 92.3 0.8 1.0 900.9 0.0 1.5 0.0 17.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 791.9 2.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 10.3 4.0 0.0 0.0 0.2 933.7 556.9 0.0 0.4 209.4 300.6 0.0 0.5 0.2 0.0 2.1 9.2 0.0 0.1 0.0 0.0 0.0 3.1 0.2 2419.9 1989.0 OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 52.3;Leydig cells: 39.7;Peritubular cells: 39.5;Sertoli cells: 26.3;Smooth muscle cells: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 31.2;U-2197: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" 21.6 6.2 1.4 5.2 1.8 0.3 12.5 2.2 1.9 27.2 7.5 8.4 5.0 19.0 21.3 8.2 17.5 23.8 14.8 1.8 1.9 6.4 10.8 18.9 9.3 2.0 1.5 48.6 2.8 2.3 3.1 7.3 1.7 14.1 10.2 0.2 5.6 18.3 5.2 8.3 7.2 18.0 1.2 14.7 5.4 4.1 2.1 3.2 8.2 12.1 5.6 14.9 17.7 2.0 0.0 0.0 0.4 0.0 1.9 1.9 31.2 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.2 0.1 0.1 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 6.4 0.0 0.0 0.1 0.2 0.1 20.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.8 0.1 0.0 0.0 1.4 1.8 2.2 1.9 1.8 1.9 2.0 1.5 1.7 1.2 2.1 2.0 6.1 0.0 0.0 1.0 0.4 5.2 0.0 0.0 1.2 0.1 0.2 0.3 1.0 0.0 0.6 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 13.3 2.9 0.0 0.0 0.1 0.0 2.0 52.3 0.0 0.4 0.0 0.0 5.0 0.9 0.6 0.0 0.1 0.0 0.0 0.0 6.1 0.7 39.7 0.4 7.2 2.8 0.0 0.0 0.0 0.5 1.4 0.1 0.0 39.5 0.2 0.1 0.0 0.3 0.0 0.0 26.3 9.4 16.3 0.3 0.1 0.2 3.7 0.3 0.7 5.0 0.0 0.1 OLFML2A FLJ00237 ENSG00000185585 "Olfactomedin like 2A" Q68BL7 9 124777133-124814885 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 40.1;Endothelial cells: 21.2;Fibroblasts: 29.0;Skeletal myocytes: 63.0;Smooth muscle cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 160.0;GAMG: 34.0;HeLa: 39.8;hTERT-RPE1: 38.0;WM-115: 64.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021180, HPA022254" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 240000 "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA021180: AB_1854790, HPA022254: AB_1854791" "unprognostic (1.12e-1)" "unprognostic (3.07e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-1)" "unprognostic (4.01e-2)" "unprognostic (1.27e-1)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (1.26e-3)" "unprognostic (7.53e-2)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (3.73e-5)" "unprognostic (5.72e-3)" "unprognostic (3.30e-2)" "unprognostic (7.91e-2)" "unprognostic (1.05e-2)" 15.4 2.9 2.6 2.7 3.1 0.3 11.1 2.2 4.6 25.0 3.3 29.9 3.3 25.3 2.8 8.2 6.4 4.8 16.4 2.2 2.4 4.3 0.7 10.5 2.4 2.8 2.1 12.0 4.8 4.6 2.8 7.0 2.8 7.4 6.2 2.2 7.0 12.2 10.8 16.0 6.9 16.0 2.1 32.8 5.5 1.1 2.6 3.1 19.1 10.0 3.7 17.6 14.6 2.1 0.8 14.6 1.2 0.4 16.8 160.0 0.1 1.8 8.2 3.5 3.5 0.2 2.2 0.0 3.4 0.1 34.0 25.5 0.4 0.8 4.0 0.0 0.1 0.0 39.8 0.1 0.9 0.0 0.1 11.3 2.7 10.2 1.4 38.0 0.0 0.0 0.0 0.2 1.8 0.4 0.0 0.3 3.4 0.0 0.9 0.0 9.5 0.0 0.0 1.2 0.0 0.1 2.9 0.2 4.3 28.6 3.9 0.5 0.1 5.2 4.6 5.5 0.7 1.9 0.0 0.1 15.2 0.8 64.1 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.1 2.6 3.1 2.2 4.6 2.2 2.4 2.8 2.1 2.8 2.1 2.6 2.1 40.1 0.0 1.3 0.7 0.4 12.0 5.9 17.5 6.2 0.6 2.9 8.3 13.8 1.5 5.5 0.0 2.1 0.3 0.5 0.0 0.0 0.1 0.7 0.2 1.5 21.2 0.0 0.0 0.4 0.6 0.3 29.0 0.5 0.2 0.0 0.9 3.6 0.1 0.1 0.0 0.6 0.0 4.1 1.5 7.9 1.4 2.8 0.9 10.6 8.4 0.1 0.3 0.0 0.0 0.1 0.0 0.0 1.5 0.1 4.0 0.0 0.1 11.5 4.0 13.1 63.0 36.4 0.4 0.7 4.5 8.4 0.0 0.6 4.2 0.0 3.5 OLFML2B DKFZP586L151 ENSG00000162745 "Olfactomedin like 2B" Q68BL8 1 161983192-162023869 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 48.3" "Cell type enhanced" "Detected in many" "Early spermatids: 122.5;Hofbauer cells: 38.4;Skeletal myocytes: 175.5;Smooth muscle cells: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 6.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 11 "monocytes: 6.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.7;HSkMC: 113.3;RH-30: 88.5" "Group enriched" "Detected in all" 4 "hippocampal formation: 41.0;white matter: 11.9" "Low region specificity" "Detected in all" "HPA054136, HPA062739" Approved Approved Cytosol "Secreted - unknown location" NA NA 12000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA054136: AB_2682397, HPA062739: AB_2684858" "unprognostic (2.97e-2)" "unprognostic (1.79e-1)" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (6.01e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (5.97e-3)" "unprognostic (7.32e-2)" "unprognostic (7.68e-3)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.01e-12)" "unprognostic (1.64e-3)" "unprognostic (2.11e-2)" "unprognostic (4.53e-3)" "unprognostic (1.97e-2)" 23.4 6.9 4.2 19.2 7.5 0.4 14.7 2.4 5.6 16.8 6.0 18.3 2.1 16.2 5.0 3.9 11.4 48.3 6.6 5.7 3.4 3.1 0.8 15.3 14.0 3.7 4.0 4.2 1.4 3.5 2.8 40.6 4.7 5.3 2.9 0.2 10.4 6.9 10.2 10.1 5.5 22.0 3.0 10.2 3.3 15.9 9.8 3.7 20.8 6.5 11.2 16.8 7.3 4.2 0.1 0.4 6.6 2.2 21.0 39.7 0.0 2.3 10.6 4.3 11.8 0.0 0.2 0.0 0.3 25.7 4.3 0.0 0.6 0.1 2.5 0.0 0.8 0.5 0.2 0.0 0.3 0.1 0.8 113.3 0.0 5.3 0.0 2.1 0.7 0.0 0.0 1.0 19.3 0.1 0.1 0.2 2.1 0.0 1.0 0.2 88.5 8.9 1.6 0.1 0.8 0.3 9.1 0.0 0.6 19.6 0.0 0.1 0.1 2.7 0.7 4.0 3.6 0.0 0.1 0.0 25.1 2.7 1.3 0.0 0.4 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 5.5 0.0 0.0 0.2 4.2 7.5 2.4 5.6 5.7 3.4 3.7 4.0 4.7 3.0 9.8 4.2 4.1 0.0 0.6 0.0 0.2 3.3 0.1 0.1 0.0 0.1 0.4 1.0 3.0 1.5 0.7 1.8 0.0 0.3 0.1 0.0 0.0 0.0 122.5 1.2 24.9 1.7 0.0 0.4 2.8 0.0 0.3 21.9 0.0 0.7 1.3 1.1 1.1 0.2 38.4 0.0 0.9 0.1 0.0 31.1 9.0 12.9 20.8 16.6 1.8 8.4 0.9 0.8 0.0 0.0 2.9 0.0 0.0 29.3 0.1 0.1 0.0 0.1 0.1 0.1 6.6 175.5 57.2 8.8 1.7 0.1 2.3 0.3 0.6 16.4 0.0 0.0 OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 136.6;Fibroblasts: 246.9;Leydig cells: 73.3;Theca cells: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 577.3;ASC TERT1: 312.6;BJ hTERT+: 374.8;HSkMC: 581.6;LHCN-M2: 602.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" 85.6 42.6 5.7 24.9 7.4 0.9 89.7 7.2 12.4 170.6 8.2 71.9 15.1 124.7 42.6 26.6 96.3 95.0 56.6 5.4 6.7 34.1 36.3 55.4 12.0 9.8 7.7 177.4 35.2 9.9 17.9 111.8 8.6 42.9 34.5 0.2 16.7 73.8 10.3 37.6 32.3 94.6 9.2 9.9 48.4 9.3 9.7 8.9 21.8 38.2 14.9 71.1 98.8 11.2 0.0 19.7 9.7 0.1 577.3 312.6 0.6 77.1 374.8 26.5 85.3 25.2 0.2 0.0 4.1 222.4 0.2 0.0 3.2 0.3 4.0 0.0 0.0 0.0 0.1 19.3 149.6 0.2 0.0 581.6 0.0 37.2 0.5 10.7 2.1 0.0 0.0 0.1 602.3 0.3 0.2 0.4 45.8 0.0 0.7 0.1 142.6 0.3 0.0 0.0 0.3 5.4 0.1 0.2 10.5 143.3 224.6 0.9 1.8 14.9 27.6 5.9 0.0 0.2 0.1 0.0 7.3 0.0 94.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 7.4 7.2 12.4 5.4 6.7 9.8 7.7 8.6 9.2 9.7 11.2 13.6 0.0 3.7 0.0 0.4 13.0 0.2 0.0 0.6 0.0 2.1 2.9 1.4 4.3 0.8 1.8 0.0 6.8 1.1 0.2 0.0 0.8 2.9 6.2 136.6 9.5 6.0 0.0 0.0 0.0 4.9 246.9 5.6 3.5 1.3 0.3 45.7 0.5 33.3 0.0 0.0 0.6 0.0 5.9 22.7 1.7 73.3 15.5 12.4 16.9 0.6 0.0 0.0 0.0 0.1 0.3 0.1 33.1 0.2 0.7 0.0 0.5 0.0 0.1 0.0 44.8 28.0 0.3 0.4 1.2 11.5 12.4 2.6 126.1 0.2 0.2 OLIG1 "BHLHB6, bHLHe21" ENSG00000184221 "Oligodendrocyte transcription factor 1" Q8TAK6 21 33070141-33072413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 178.0" "Cell type enhanced" "Detected in some" "Distal tubular cells: 64.6;Oligodendrocyte precursor cells: 371.5;Oligodendrocytes: 134.7" "Cancer enriched" "Detected in some" 18 "glioma: 116.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 12.1;eosinophil: 37.6" "Lineage enriched" "Detected in many" 15 "granulocytes: 37.6" "Group enriched" "Detected in some" 6 "NB-4: 39.2;RPMI-8226: 20.8;THP-1: 25.5;U-937: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 24: NB-4 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (4.13e-2)" "unprognostic (6.46e-2)" "unprognostic (4.06e-1)" "unprognostic (3.58e-1)" "unprognostic (9.01e-3)" "unprognostic (2.40e-1)" "unprognostic (7.93e-2)" "unprognostic (1.50e-1)" "unprognostic (3.82e-3)" "unprognostic (5.19e-2)" "unprognostic (8.17e-2)" "unprognostic (2.51e-1)" "unprognostic (4.05e-2)" "unprognostic (5.96e-3)" "unprognostic (3.20e-2)" "unprognostic (1.17e-1)" 0.0 0.0 126.5 0.1 168.1 0.8 0.0 132.7 127.3 0.0 34.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 103.6 121.3 2.8 0.1 0.7 0.0 154.2 156.5 0.0 0.1 0.0 0.5 0.0 128.1 0.0 0.0 0.0 0.2 0.0 1.3 0.8 0.1 0.0 118.4 0.6 0.2 2.0 144.5 0.0 0.0 0.6 0.0 0.1 0.0 178.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 2.6 0.7 0.0 0.0 0.0 0.0 1.8 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 39.2 0.2 0.0 0.0 0.0 0.1 20.8 0.0 0.0 1.3 0.0 0.0 0.0 4.7 0.0 0.2 25.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 29.1 1.6 12.1 2.4 37.6 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 2.5 0.1 0.0 0.6 126.5 168.1 132.7 127.3 103.6 121.3 154.2 156.5 128.1 118.4 144.5 178.0 0.0 0.0 0.0 13.7 0.3 0.0 0.1 0.0 0.0 0.0 0.9 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.6 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 1.8 0.0 0.0 3.2 0.0 0.5 0.0 2.4 5.4 1.0 24.1 0.0 1.0 371.5 134.7 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.4 0.0 2.7 3.3 0.0 0.1 0.1 0.1 0.0 0.0 0.1 OMG OMGP ENSG00000126861 "Oligodendrocyte myelin glycoprotein" P23515 17 31272013-31297539 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 116.5;choroid plexus: 44.1" "Group enriched" "Detected in many" 5 "Endometrial ciliated cells: 458.9;Respiratory ciliated cells: 708.8" "Group enriched" "Detected in some" 7 "endometrial cancer: 3.5;glioma: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008206, HPA012693" Enhanced "Intracellular and membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 49: Ciliated cells - Cilium organization" "HPA008206: AB_1854240, HPA012693: AB_1854239" "unprognostic (8.05e-4)" "unprognostic (2.11e-2)" "unprognostic (1.27e-1)" "unprognostic (3.03e-3)" "unprognostic (1.85e-1)" "unprognostic (4.16e-2)" "unprognostic (1.63e-1)" "unprognostic (3.81e-2)" "unprognostic (9.54e-2)" "unprognostic (8.60e-2)" "unprognostic (7.03e-2)" "unprognostic (1.52e-1)" "unprognostic (3.96e-13)" "unprognostic (7.80e-3)" "unprognostic (6.00e-2)" "unprognostic (3.24e-1)" "unprognostic (2.42e-2)" 0.0 0.1 69.7 0.0 78.1 0.7 0.0 70.7 116.5 0.0 44.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 71.9 71.6 0.0 0.0 0.1 0.0 68.6 66.5 0.0 0.0 0.0 0.3 0.0 71.5 0.0 0.1 19.5 0.0 0.0 0.0 0.0 0.1 0.0 69.6 0.3 0.1 0.0 70.5 0.0 0.0 0.0 0.0 0.0 0.0 88.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.7 78.1 70.7 116.5 71.9 71.6 68.6 66.5 71.5 69.6 70.5 88.4 0.5 0.0 3.7 18.3 0.3 0.4 0.0 72.8 0.0 4.2 0.1 0.1 0.7 0.0 44.2 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.1 458.9 3.8 1.6 0.0 0.0 28.0 0.0 0.6 1.5 0.0 7.0 0.0 0.0 0.7 0.1 0.5 0.0 18.7 0.0 61.1 20.1 0.7 0.0 0.0 1.1 0.0 3.7 0.2 78.2 1.0 78.4 101.8 0.0 0.0 0.0 0.9 0.0 0.0 0.1 708.8 2.4 0.0 0.7 19.1 0.0 0.0 0.2 0.1 11.8 1.4 0.0 0.0 0.0 OOSP1 ENSG00000284873 "Oocyte secreted protein 1" 11 59938432-59957480 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.2;Inhibitory neurons: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "THP-1: 1.2" "Not detected" "Not detected" NA NA "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OOSP2 "FLJ36198, OOSP2A, PLAC1L, TMEM122" ENSG00000149507 "Oocyte secreted protein 2" Q86WS3 11 60040409-60048044 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 180 "testis: 18.0" "Cell type enriched" "Detected in some" 5 "Late spermatids: 7.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA050914 Enhanced "Secreted in male reproductive system" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA050914: AB_2681271" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OOSP3 ENSG00000285231 "Oocyte secreted protein family member 3" A0A2R8YFM6 11 59878809-59896481 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "basophil: 5.5" "Lineage enriched" "Detected in single" 55 "granulocytes: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA "Cluster 41: Basophils - Cellular respiration" 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OOSP4A ENSG00000285010 "Oocyte secreted protein family member 4A" A0A2R8YFL7 11 59964033-59970146 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "basophil: 4.1" "Lineage enriched" "Detected in single" 12 "granulocytes: 4.1" "Group enriched" "Detected in some" 5 "HEL: 1.0;K-562: 2.6" "Secreted - unknown location" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 1: K-562 - Erythropoiesis" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.2 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OPA1 "FLJ12460, KIAA0567, MGM1, NPG, NTG" ENSG00000198836 "OPA1 mitochondrial dynamin like GTPase" O60313 3 193593144-193697811 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Sensory transduction, Vision" Hydrolase "Cardiomyopathy, Deafness, Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 135.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036926, HPA036927" Supported Supported Nucleoplasm,Mitochondria NA NA 10000 "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Mitochondria" "HPA036926: AB_10671247, HPA036927: AB_2675388" "unprognostic (2.10e-2)" "unprognostic (9.23e-3)" "unprognostic (7.98e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (1.62e-2)" "unprognostic (4.59e-2)" "unprognostic (2.24e-1)" "unprognostic (1.86e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (3.48e-2)" "prognostic favorable (1.84e-4)" "unprognostic (2.92e-1)" "unprognostic (4.75e-1)" "unprognostic (4.50e-3)" "unprognostic (3.21e-1)" 15.0 12.0 14.3 7.6 17.4 25.6 12.8 15.2 19.5 10.4 9.4 18.9 16.8 10.9 9.1 14.6 8.1 10.2 39.3 18.6 17.4 18.3 20.9 8.5 11.8 16.4 15.4 8.4 10.1 23.1 3.8 11.7 16.8 12.3 16.6 9.6 11.7 13.3 24.2 11.9 13.8 13.5 12.4 9.3 14.6 6.3 15.2 12.7 13.9 44.5 12.4 13.0 5.1 13.7 58.9 18.8 18.2 20.2 15.8 25.0 19.3 27.5 26.2 30.0 29.0 45.2 19.3 38.6 58.1 27.0 27.3 37.3 32.7 31.7 53.5 46.5 25.7 67.9 16.7 23.1 24.9 55.8 29.8 28.4 27.6 30.0 40.9 18.5 26.2 15.7 28.4 37.0 30.2 46.5 21.9 30.9 25.8 33.9 59.9 27.8 40.1 41.6 22.7 36.1 39.8 24.2 41.8 46.3 29.5 14.1 60.3 43.5 26.3 27.7 20.8 29.3 58.7 33.1 41.3 74.0 30.5 43.7 28.4 9.7 7.3 7.1 5.8 8.2 5.5 6.8 5.5 5.6 7.8 5.1 5.6 6.0 2.7 4.7 17.3 4.0 6.6 5.2 14.3 17.4 15.2 19.5 18.6 17.4 16.4 15.4 16.8 12.4 15.2 13.7 24.8 16.0 24.0 72.1 27.5 15.9 16.4 17.4 24.5 19.5 20.9 13.5 135.2 22.8 20.1 18.4 31.3 19.0 24.6 31.4 17.6 19.3 7.7 20.3 25.2 23.8 23.4 86.3 106.8 24.0 14.9 24.6 31.1 26.1 19.6 25.6 14.3 39.1 17.9 21.9 106.7 20.6 10.2 25.6 14.7 13.5 15.8 28.1 21.4 58.1 22.9 14.6 11.3 87.4 98.1 28.9 12.1 14.7 29.3 18.7 24.6 34.1 19.6 23.4 6.6 21.3 26.2 15.1 16.6 34.3 22.4 17.9 22.3 28.2 26.7 22.1 OPALIN "HTMP10, TMEM10, TMP10" ENSG00000197430 "Oligodendrocytic myelin paranodal and inner loop protein" Q96PE5 10 96343221-96359365 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 654 "brain: 166.5;choroid plexus: 47.8" "Cell type enriched" "Detected in some" 304 "Oligodendrocytes: 304.5" "Cancer enriched" "Detected in single" 36 "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "REH: 1.0" "Region enhanced" "Detected in all" "white matter: 240.1" "Low region specificity" "Detected in all" HPA014372 Supported NA NA "Cluster 65: Brain - Ion transport" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA014372: AB_2158172" "unprognostic (1.18e-1)" 0.0 0.0 112.6 0.0 135.3 0.0 0.0 58.9 166.5 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.9 86.6 0.0 0.0 0.0 0.0 101.3 106.0 0.0 0.0 0.0 0.1 0.0 83.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.4 0.0 0.0 0.0 94.9 0.0 0.0 0.0 0.0 0.0 0.0 149.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.6 135.3 58.9 166.5 104.9 86.6 101.3 106.0 83.4 72.4 94.9 149.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 304.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OPCML "IGLON1, OBCAM, OPCM" ENSG00000183715 "Opioid binding protein/cell adhesion molecule like" Q14982 11 132414977-133532519 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 39.2;parathyroid gland: 10.3;retina: 11.6" "Group enriched" "Detected in some" 34 "Excitatory neurons: 2120.9;Inhibitory neurons: 1900.4;Oligodendrocyte precursor cells: 3173.2" "Cancer enriched" "Detected in some" 4 "glioma: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "BJ: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 7100000 "Cluster 6: Brain - Smell perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.59e-1)" "unprognostic (2.26e-2)" "unprognostic (3.70e-2)" "unprognostic (3.31e-4)" "unprognostic (8.23e-2)" "unprognostic (3.53e-2)" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (8.46e-3)" "unprognostic (2.59e-2)" "unprognostic (2.80e-1)" "unprognostic (4.73e-2)" "unprognostic (1.11e-2)" "unprognostic (1.13e-2)" "unprognostic (1.76e-1)" "unprognostic (9.71e-2)" "unprognostic (2.19e-1)" 0.2 0.4 13.2 0.1 16.6 0.0 0.1 22.3 39.2 0.4 0.0 0.1 0.1 0.6 0.1 0.4 0.5 0.2 0.3 18.4 3.1 1.4 0.0 0.0 0.0 0.0 5.1 0.3 0.0 10.3 1.3 0.0 0.0 0.1 0.1 11.6 0.2 0.6 0.1 0.1 0.1 0.5 0.2 0.7 0.2 0.4 9.6 0.0 0.1 0.3 0.0 0.1 0.1 13.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 9.4 0.0 1.4 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 16.6 22.3 39.2 18.4 3.1 0.0 5.1 0.0 0.2 9.6 13.4 0.0 0.0 0.0 25.5 0.0 0.1 0.0 0.0 0.0 40.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 6.7 0.0 0.0 0.4 0.0 0.0 2120.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 1.7 1900.4 0.0 0.0 0.3 0.4 14.9 0.0 0.1 0.0 69.3 0.0 1.3 0.0 3173.2 30.3 0.0 0.0 1.2 0.0 0.0 0.0 0.6 0.0 4.2 6.6 0.0 1.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 OPRPN "BPLP, PRL1, PROL1" ENSG00000171199 "Opiorphin prepropeptide" Q99935 4 70397931-70410195 "Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 146.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 12.5;Breast myoepithelial cells: 3.3;Glandular and luminal cells: 2.1" "Group enriched" "Detected in some" 5 "breast cancer: 7.4;liver cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA065711 Approved "Secreted in other tissues" NA NA 63000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: Glandular cells - Unknown function" "HPA065711: AB_2685541" "unprognostic (3.11e-3)" "unprognostic (2.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 146.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 OPTC ENSG00000188770 Opticin Q9UBM4 1 203494153-203508949 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 1.5;Spermatocytes: 1.5" "Cancer enriched" "Detected in single" 6 "testis cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA034951, HPA034952" Enhanced "Secreted in other tissues" NA NA "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA034951: AB_10669852, HPA034952: AB_2674379" "unprognostic (3.29e-1)" "unprognostic (1.56e-1)" "unprognostic (7.69e-2)" "unprognostic (3.19e-2)" "unprognostic (1.70e-3)" "unprognostic (8.24e-2)" "unprognostic (3.65e-2)" 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.4 0.3 0.1 0.1 0.2 0.0 0.2 0.3 0.1 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.5 0.6 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.4 0.3 0.2 0.5 0.8 0.7 0.8 0.3 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ORM1 ENSG00000229314 "Orosomucoid 1" P02763 9 114323056-114326475 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 193 "liver: 42973.6" "Cell type enriched" "Detected in some" 46 "Hepatocytes: 58657.7" "Cancer enriched" "Detected in many" 16 "liver cancer: 2506.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 47 "neutrophil: 193.9" "Lineage enriched" "Detected in many" 47 "granulocytes: 193.9" "Cell line enriched" "Detected in some" 12 "Hep G2: 1182.7" "CAB006265, HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 945000000000 61000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "Golgi apparatus" "CAB006265: AB_425575, HPA046438: AB_2679666, HPA047725: AB_2680133, HPA057726: AB_2683512" "unprognostic (3.85e-1)" "unprognostic (2.12e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (1.16e-1)" "unprognostic (4.85e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (2.35e-4)" "unprognostic (2.10e-1)" "unprognostic (4.38e-2)" "unprognostic (9.32e-3)" "unprognostic (4.51e-2)" 13.4 10.3 0.1 12.7 0.3 223.1 6.6 0.0 0.4 2.7 0.2 1.5 0.1 2.7 0.3 1.9 1.9 1.0 3.4 0.2 0.2 4.9 42973.6 24.4 0.7 0.4 0.2 1.6 8.1 0.0 1.4 1.3 0.1 57.6 0.0 1.1 1.4 0.0 2.0 1.7 2.3 0.3 0.2 51.3 19.2 2.7 0.1 1.2 2.8 0.3 0.1 1.6 2.2 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 2.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 3.4 0.6 1182.7 0.1 5.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 0.0 0.2 0.0 0.2 1.0 0.1 0.0 0.7 7.1 0.0 0.0 0.4 0.0 0.0 5.7 5.5 0.0 0.0 0.4 102.0 1.2 0.0 0.5 0.0 0.0 1.2 0.6 3.5 0.0 4.3 0.1 0.0 4.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 193.9 0.0 1.0 0.0 0.0 1.8 0.1 0.3 0.0 0.4 0.2 0.2 0.4 0.2 0.1 0.2 0.1 0.2 0.0 3.2 18.1 0.0 81.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1166.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.0 1.3 0.2 34.4 0.0 890.4 0.0 4.9 0.3 0.2 0.0 2.5 0.0 0.0 930.9 58657.7 0.1 0.0 0.0 0.0 0.0 1260.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 29.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.0 0.3 ORM2 "AGP-B, AGP-B', AGP2" ENSG00000228278 "Orosomucoid 2" P19652 9 114329869-114333251 "Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 327 "liver: 8873.2" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 10792.5" "Cancer enriched" "Detected in many" 34 "liver cancer: 873.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 40 "neutrophil: 12.0" "Lineage enriched" "Detected in single" 40 "granulocytes: 12.0" "Cell line enriched" "Detected in some" 232 "Hep G2: 831.1" "HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 422000000 41000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus" "HPA046438: AB_2679666, HPA047725: AB_2680133, HPA057726: AB_2683512" "unprognostic (6.77e-2)" "unprognostic (8.00e-2)" "unprognostic (1.19e-1)" "unprognostic (4.44e-3)" "unprognostic (1.18e-1)" "unprognostic (5.61e-2)" "unprognostic (5.66e-2)" "unprognostic (9.70e-2)" "unprognostic (3.05e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (5.76e-2)" "prognostic unfavorable (1.23e-9)" "unprognostic (3.23e-1)" "unprognostic (6.80e-2)" "unprognostic (7.62e-2)" "unprognostic (9.15e-4)" 4.0 4.0 0.2 3.2 0.4 27.1 3.0 0.0 0.2 1.3 0.2 0.3 0.2 2.1 0.1 0.4 0.4 0.6 0.8 0.1 0.1 1.7 8873.2 5.8 1.1 0.2 0.3 0.3 2.1 0.0 0.2 0.2 0.1 23.6 0.1 3.6 0.3 0.0 0.4 0.4 0.4 0.1 0.2 7.3 21.9 1.4 0.1 0.5 0.3 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.0 831.1 0.0 3.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.2 0.0 0.0 0.1 1.1 0.4 2.5 0.0 0.3 1.9 0.1 0.0 0.3 0.1 0.0 2.6 2.0 0.2 0.1 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.7 0.6 2.2 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.1 0.0 0.0 0.1 0.2 0.4 0.0 0.2 0.1 0.1 0.2 0.3 0.1 0.2 0.1 0.2 0.0 0.0 10.5 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 263.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 6.6 1.1 0.1 7.0 0.0 141.7 0.0 6.0 0.0 0.0 15.8 1.3 0.0 0.0 162.8 10792.5 0.0 0.0 0.0 0.0 0.0 236.1 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.2 ORMDL2 "adoplin-2, HSPC160, MST095, MSTP095" ENSG00000123353 "ORMDL sphingolipid biosynthesis regulator 2" Q53FV1 12 55818041-55821879 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (1.12e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" "prognostic favorable (3.30e-5)" "unprognostic (6.92e-2)" "unprognostic (1.52e-3)" "prognostic unfavorable (9.75e-4)" "unprognostic (1.45e-2)" "unprognostic (1.11e-1)" "unprognostic (2.88e-2)" "unprognostic (1.84e-3)" "unprognostic (1.49e-1)" "unprognostic (2.75e-3)" "unprognostic (1.25e-1)" "unprognostic (2.20e-1)" "unprognostic (3.04e-2)" "unprognostic (5.68e-2)" 37.5 38.1 14.6 24.2 17.0 20.4 31.3 18.3 20.5 30.0 24.7 44.5 27.2 28.4 51.3 75.9 26.3 20.6 30.1 14.8 18.4 40.7 47.5 35.5 23.0 19.0 18.0 16.8 32.9 44.5 29.7 22.3 18.5 30.8 48.4 14.8 40.2 23.2 19.7 36.4 30.2 26.4 17.2 33.2 32.9 42.7 18.3 27.6 27.4 11.1 38.5 41.7 36.8 20.2 55.9 103.5 43.1 22.4 81.2 40.4 47.7 66.5 66.0 57.0 49.9 116.6 133.8 34.5 69.3 80.7 58.5 100.3 34.6 138.7 56.6 35.9 51.4 46.7 89.7 65.9 85.8 56.7 47.4 50.9 125.2 99.9 103.3 73.3 81.0 38.2 25.0 91.1 73.7 89.3 34.8 25.3 20.9 87.8 82.0 22.8 34.5 88.4 149.8 159.1 37.4 23.8 84.9 99.9 38.4 64.8 120.0 40.1 59.4 30.5 42.6 36.4 42.7 43.6 39.1 28.1 48.9 22.4 43.1 50.4 73.0 107.1 86.5 92.8 76.8 93.2 82.1 92.1 73.4 76.1 67.8 81.5 91.8 74.1 108.7 119.9 107.8 72.1 14.6 17.0 18.3 20.5 14.8 18.4 19.0 18.0 18.5 17.2 18.3 20.2 43.1 73.7 38.3 1.3 39.8 23.3 71.9 132.9 15.4 9.9 43.1 30.0 3.9 45.8 99.4 53.3 12.5 74.7 49.6 125.7 29.4 133.7 171.0 77.9 25.7 42.0 46.1 26.5 0.7 168.1 117.5 22.0 28.1 86.0 51.9 14.0 35.3 82.2 125.3 8.4 0.8 66.7 69.2 42.5 49.1 68.0 25.4 57.4 56.9 2.8 111.4 24.8 77.2 1.0 4.0 197.4 133.5 23.3 50.8 95.7 89.7 76.0 149.2 18.4 19.7 13.5 32.9 107.0 61.7 50.6 33.4 151.6 44.6 30.5 56.2 91.3 OS9 "ERLEC2, OS-9" ENSG00000135506 "OS9 endoplasmic reticulum lectin" Q13438 12 57693955-57721557 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 7 "RH-30: 3551.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011518, HPA013694" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 10000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB011518: AB_776918, HPA013694: AB_1854812" "unprognostic (1.67e-2)" "unprognostic (4.20e-1)" "unprognostic (3.93e-2)" "unprognostic (1.50e-1)" "unprognostic (9.79e-3)" "unprognostic (1.32e-3)" "unprognostic (4.78e-2)" "unprognostic (8.54e-2)" "unprognostic (2.67e-1)" "unprognostic (1.64e-1)" "unprognostic (5.67e-3)" "unprognostic (2.23e-1)" "unprognostic (1.83e-2)" "unprognostic (2.78e-1)" "unprognostic (1.67e-2)" "unprognostic (4.81e-2)" "unprognostic (2.21e-2)" 151.0 93.0 61.1 118.6 59.3 149.0 113.4 60.7 60.8 135.6 94.3 158.1 149.9 101.2 141.4 105.2 109.6 106.2 111.0 58.4 71.5 114.8 264.5 130.0 89.7 64.5 62.8 124.6 270.0 171.6 71.5 141.3 63.5 116.4 132.6 75.5 189.0 102.1 59.6 119.8 143.2 110.2 60.8 106.0 137.2 38.9 66.7 72.6 129.4 65.5 94.2 119.7 103.5 63.7 86.8 170.8 86.2 214.4 440.4 295.6 190.5 211.9 268.4 153.4 154.6 180.2 274.5 110.0 345.3 255.2 118.5 152.9 81.3 137.5 121.2 142.0 97.6 124.0 115.3 164.8 287.1 196.9 307.3 273.7 217.6 150.7 152.6 529.4 258.6 71.7 96.0 427.9 162.2 149.5 53.7 239.7 97.7 172.0 121.2 69.8 3551.9 281.5 116.5 210.6 88.4 116.4 300.3 205.5 176.6 158.1 245.4 381.0 238.9 206.0 122.3 140.4 136.4 253.4 234.6 112.9 173.8 141.6 290.4 175.7 241.2 274.6 72.9 213.0 68.5 50.5 61.1 65.0 172.6 54.3 46.8 54.1 246.4 58.8 182.4 149.0 74.4 218.9 61.1 59.3 60.7 60.8 58.4 71.5 64.5 62.8 63.5 60.8 66.7 63.7 83.3 86.6 116.7 22.2 65.8 57.7 85.4 103.3 43.9 44.1 61.2 46.6 14.1 80.1 111.8 73.5 77.2 142.4 64.5 153.0 9.8 144.8 6.7 34.0 73.3 90.2 103.6 53.4 19.5 110.1 124.6 113.6 65.7 60.0 91.1 61.6 81.4 161.1 144.8 50.5 27.0 167.3 107.8 121.1 99.1 10.7 113.4 106.1 119.2 29.0 125.0 87.2 53.5 23.6 24.4 94.7 155.4 79.0 141.1 56.5 154.0 53.9 74.0 50.9 92.1 68.3 66.9 38.1 46.4 51.3 51.6 197.7 59.5 64.9 102.4 65.0 OSBP2 "KIAA1664, ORP-4, ORP4, OSBPL1" ENSG00000184792 "Oxysterol binding protein 2" Q969R2 22 30693782-30907824 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.7;retina: 160.8" "Cell type enhanced" "Detected in many" "Early spermatids: 135.4;Excitatory neurons: 132.8;Inhibitory neurons: 156.3;Late spermatids: 304.4;Oligodendrocytes: 182.8;Rod photoreceptor cells: 619.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 41.9;HeLa: 146.4;hTERT-HME1: 38.2;SiHa: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021514 Uncertain Approved Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA021514: AB_1854813" "unprognostic (2.89e-1)" "unprognostic (2.04e-1)" "unprognostic (2.83e-1)" "unprognostic (6.94e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (1.38e-5)" "unprognostic (3.01e-1)" "unprognostic (2.57e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-1)" "unprognostic (2.31e-1)" "prognostic favorable (3.79e-6)" "unprognostic (9.00e-2)" "unprognostic (2.68e-1)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" 1.4 11.8 6.2 2.8 14.4 52.7 1.5 17.0 20.5 1.6 2.1 1.7 7.5 2.0 14.6 3.7 2.0 3.0 12.2 8.5 4.4 2.6 1.0 1.6 2.3 9.6 9.8 1.6 5.0 9.3 20.9 4.6 10.0 2.3 1.7 160.8 2.9 2.4 2.8 5.4 5.6 1.2 1.8 4.8 3.5 28.7 21.3 0.6 3.2 3.2 1.3 4.4 2.1 15.1 7.1 15.4 1.5 6.7 1.0 5.8 1.6 1.3 3.1 4.8 4.8 14.0 3.9 12.5 5.7 1.9 1.5 4.1 6.2 0.6 3.5 6.7 1.8 41.9 146.4 2.7 0.9 0.2 2.5 0.3 16.8 11.8 38.2 1.6 12.1 4.8 26.7 0.5 11.0 7.8 1.3 4.5 3.8 3.3 13.8 3.5 0.5 0.7 0.6 2.7 16.7 6.8 39.2 4.1 0.4 2.9 4.9 2.2 8.8 3.4 18.1 3.2 6.8 3.2 4.8 2.3 13.3 0.0 2.7 0.0 0.7 0.4 0.5 1.1 1.0 0.5 1.0 0.4 0.6 0.6 1.0 1.1 0.7 1.0 0.9 0.2 0.7 2.0 6.2 14.4 17.0 20.5 8.5 4.4 9.6 9.8 10.0 1.8 21.3 15.1 1.2 0.0 3.1 37.9 0.2 5.2 0.9 0.4 0.6 93.2 1.3 0.8 11.2 2.8 1.0 1.8 81.3 0.2 0.3 1.3 1.9 1.8 135.4 1.6 0.5 2.8 7.2 91.3 132.8 1.5 0.2 1.6 2.0 1.6 0.0 3.2 0.4 0.1 0.2 18.5 156.3 2.8 0.0 0.3 1.8 304.4 2.5 1.7 1.8 8.4 0.4 31.4 0.0 35.7 182.8 0.8 5.2 1.9 1.4 1.2 0.7 0.8 1.3 619.5 0.0 1.1 2.3 48.6 4.4 1.4 9.5 0.3 0.5 1.2 1.2 1.3 OSCAR ENSG00000170909 "Osteoclast associated Ig-like receptor" Q8IYS5 19 54094668-54102692 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 13.6;lung: 28.4;lymphoid tissue: 29.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 35.6;Kupffer cells: 27.8;Macrophages: 42.9;monocytes: 66.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 36 "classical monocyte: 43.0;eosinophil: 26.6;intermediate monocyte: 28.8;myeloid DC: 20.3;neutrophil: 40.0;non-classical monocyte: 27.0" "Group enriched" "Detected in many" 79 "dendritic cells: 20.3;granulocytes: 40.0;monocytes: 43.0" "Cell line enhanced" "Detected in some" "EFO-21: 13.9;HHSteC: 9.4;hTERT-HME1: 5.0;NB-4: 5.9;U-937: 17.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073996 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 84000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA073996: " "unprognostic (9.09e-2)" "unprognostic (6.79e-3)" "unprognostic (8.47e-3)" "unprognostic (2.14e-1)" "unprognostic (2.12e-2)" "unprognostic (9.04e-2)" "unprognostic (1.39e-1)" "unprognostic (3.86e-1)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.05e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.71e-5)" "unprognostic (1.84e-1)" "unprognostic (2.88e-2)" "unprognostic (9.69e-2)" "unprognostic (4.28e-2)" 3.7 1.8 0.9 2.3 0.7 13.6 1.8 0.1 1.6 2.2 0.0 1.5 0.0 1.3 0.0 1.5 3.2 1.3 1.9 0.1 0.7 1.5 2.4 28.4 0.3 1.3 0.7 1.1 1.3 0.1 1.0 0.6 0.9 1.7 0.3 0.0 2.2 0.3 0.5 2.1 1.6 1.7 0.7 29.8 1.2 0.9 0.8 0.2 1.1 0.6 0.6 2.2 2.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.3 0.0 13.9 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 9.4 0.6 0.0 0.0 0.2 0.6 5.0 0.8 0.0 0.0 0.0 0.4 0.1 0.1 0.0 5.9 0.3 0.1 1.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.8 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.6 0.5 17.9 0.0 0.0 43.0 26.6 0.3 28.8 0.1 0.0 0.2 0.4 20.3 0.0 0.1 0.0 40.0 0.0 27.0 0.8 0.2 16.8 0.9 0.7 0.1 1.6 0.1 0.7 1.3 0.7 0.9 0.7 0.8 1.7 0.2 3.2 5.9 0.3 0.3 0.8 0.6 0.7 0.6 0.0 0.7 0.4 0.3 1.5 2.1 0.0 0.0 0.3 0.6 0.1 0.0 0.3 0.0 0.1 0.3 0.9 0.0 1.7 1.9 0.0 0.4 0.6 0.0 0.1 1.3 0.3 0.0 0.0 35.6 0.0 1.0 0.3 0.0 27.8 11.6 0.2 0.0 42.9 0.0 1.0 66.4 0.0 1.0 0.0 0.3 0.4 0.0 0.0 0.4 0.3 0.1 0.2 3.7 0.4 0.0 0.2 0.1 0.6 0.5 0.4 0.1 0.3 0.7 0.4 0.1 0.3 OSM MGC20461 ENSG00000099985 "Oncostatin M" P13725 22 30262829-30266851 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Cytokine, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 118.2" "Group enriched" "Detected in some" 4 "Hofbauer cells: 74.4;Macrophages: 51.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 65.2;neutrophil: 34.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 65.2" "Cell line enhanced" "Detected in some" "HDLM-2: 15.7;HL-60: 3.8;HMC-1: 11.1;Karpas-707: 3.5;NB-4: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 39700 "Cluster 38: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.15e-2)" "unprognostic (8.80e-3)" "unprognostic (1.01e-1)" "unprognostic (6.02e-2)" "unprognostic (7.37e-2)" "unprognostic (2.61e-2)" "unprognostic (6.78e-2)" "unprognostic (3.77e-2)" "unprognostic (2.81e-2)" "unprognostic (4.60e-2)" "unprognostic (1.58e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.00e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-1)" "unprognostic (1.82e-1)" 7.2 3.6 0.8 14.3 1.0 118.2 0.8 0.8 4.2 1.2 2.0 1.0 0.5 1.1 0.1 0.8 2.3 6.2 1.4 0.6 1.5 2.0 1.9 7.8 1.6 1.8 0.9 0.5 1.2 0.9 1.5 5.5 1.7 1.0 0.5 0.1 1.1 0.2 0.2 0.2 0.7 3.1 1.6 5.0 0.9 0.4 4.7 2.6 0.8 2.9 0.8 12.7 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.7 0.0 0.3 0.0 0.0 0.0 3.8 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 3.5 0.0 0.0 0.5 6.6 0.0 0.0 0.0 0.6 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.3 0.0 65.2 0.5 2.0 2.0 0.3 6.5 0.0 4.8 2.6 0.8 0.2 0.9 2.4 34.9 4.3 0.1 0.2 1.4 1.6 0.8 1.0 0.8 4.2 0.6 1.5 1.8 0.9 1.7 1.6 4.7 2.9 0.9 9.6 10.6 0.0 3.2 0.8 0.2 0.0 0.0 0.0 0.7 1.8 0.6 0.0 3.7 0.0 0.0 0.8 13.2 0.0 0.0 0.1 0.1 0.6 0.2 1.9 0.0 1.3 0.1 0.0 0.9 1.4 0.0 1.1 15.2 0.0 0.4 0.0 74.4 0.0 0.1 0.1 0.0 6.1 12.4 0.0 0.0 51.6 0.0 0.0 1.8 0.1 1.0 0.0 0.1 0.1 0.1 0.0 2.5 0.1 0.0 0.1 0.7 0.2 0.0 0.7 0.4 0.0 0.0 0.3 0.3 0.8 14.2 0.1 0.0 0.0 OSMR "OSMRB, OSMRbeta" ENSG00000145623 "Oncostatin M receptor" Q99650 5 38845858-38945596 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 74.9;Pancreatic endocrine cells: 72.4;Prostatic glandular cells: 73.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 154.3;GAMG: 162.7;HSkMC: 192.7;U-2197: 158.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017278 Approved Approved Nucleoli "Intracellular and membrane" NA NA 51000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoli "HPA017278: AB_1854818" "unprognostic (6.34e-3)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.58e-1)" "unprognostic (2.11e-1)" "unprognostic (2.18e-3)" "unprognostic (1.13e-1)" "unprognostic (8.00e-3)" "unprognostic (5.70e-2)" "unprognostic (1.79e-3)" "unprognostic (1.72e-3)" "unprognostic (1.60e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.96e-6)" "unprognostic (1.88e-2)" "unprognostic (1.49e-2)" "unprognostic (4.43e-1)" "unprognostic (1.75e-2)" 59.3 29.8 7.8 25.3 7.6 0.1 37.3 7.4 8.4 26.0 9.7 25.2 5.5 22.9 7.6 17.1 27.8 28.8 27.6 6.5 10.5 29.9 19.2 46.2 16.0 13.4 10.8 24.6 16.4 6.5 10.4 35.3 10.2 24.6 10.5 4.3 27.4 13.5 11.8 21.9 15.1 39.0 9.3 17.9 18.4 5.6 11.5 13.9 23.9 8.5 15.1 40.9 22.3 8.1 32.6 41.2 6.9 17.7 72.6 154.3 23.4 51.7 81.7 49.8 66.4 0.1 85.9 0.0 23.9 55.3 162.7 43.9 8.9 63.6 79.8 0.1 5.1 2.2 31.2 31.6 82.4 0.0 0.6 192.7 37.3 111.9 94.9 92.3 7.7 0.0 0.0 0.2 31.8 8.8 0.1 0.1 1.1 6.8 13.3 0.0 2.3 0.0 99.8 9.5 0.1 0.3 116.8 0.2 0.2 9.5 35.4 0.3 12.2 120.6 45.1 158.1 28.0 0.0 0.1 0.1 96.8 0.1 26.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 7.6 7.4 8.4 6.5 10.5 13.4 10.8 10.2 9.3 11.5 8.1 41.5 44.8 56.8 13.4 0.6 30.3 74.9 55.0 27.3 0.2 21.7 10.8 5.0 15.7 51.4 12.9 0.0 6.9 0.2 0.2 0.0 48.7 0.6 6.6 38.9 47.0 0.0 0.4 2.0 48.6 6.8 37.2 6.6 9.2 1.3 2.6 55.0 16.6 1.6 0.0 1.8 0.0 8.2 6.1 7.6 1.4 41.7 1.1 7.2 46.9 1.6 0.7 0.0 13.6 3.6 72.4 0.0 7.5 0.6 73.8 0.0 5.9 19.3 0.6 19.7 32.4 33.6 0.3 1.6 10.5 24.0 17.1 1.7 4.7 0.0 57.7 OSTN ENSG00000188729 Osteocrin P61366 3 191199241-191265615 "Predicted secreted proteins" Differentiation "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Early spermatids: 4.2;Excitatory neurons: 1.0;Inhibitory neurons: 5.9;Late spermatids: 1.4;Oligodendrocyte precursor cells: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 6 "memory B-cell: 4.0;naive B-cell: 1.3" "Lineage enriched" "Detected in single" 9 "B-cells: 4.0" "Cell line enriched" "Detected in some" 24 "U-2197: 39.1" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in single" "CAB024997, CAB025649, HPA030878" Uncertain "Secreted in other tissues" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB024997: , CAB025649: , HPA030878: AB_2673642" "unprognostic (2.35e-2)" "unprognostic (9.12e-2)" "unprognostic (6.30e-2)" "unprognostic (2.34e-1)" "unprognostic (2.51e-1)" "unprognostic (3.01e-2)" "unprognostic (2.52e-1)" "unprognostic (8.11e-3)" "unprognostic (2.90e-1)" "unprognostic (1.45e-1)" 0.3 0.1 0.6 0.7 0.9 0.0 0.1 0.1 1.2 1.2 0.2 0.1 0.0 0.1 1.6 0.0 0.7 0.8 0.4 0.8 0.8 0.1 0.6 0.2 0.6 0.5 0.2 0.2 0.0 0.0 0.0 0.4 0.5 0.6 0.0 0.1 0.2 0.1 0.8 1.2 0.1 0.0 0.4 0.2 0.3 0.4 0.3 0.1 0.1 1.0 0.0 1.3 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.1 0.0 1.6 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.9 0.1 1.2 0.8 0.8 0.5 0.2 0.5 0.4 0.3 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 5.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OTOA "CT108, DFNB22" ENSG00000155719 Otoancorin Q7RTW8 16 21663968-21761935 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "lymphoid tissue: 1.8;testis: 4.0" "Cell type enhanced" "Detected in some" "Hofbauer cells: 111.8;Kupffer cells: 60.5;Late spermatids: 18.7;Macrophages: 34.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041405 Enhanced "Secreted in other tissues" NA NA 51000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 4: Macrophages - Innate immune response" "HPA041405: AB_10796344" "unprognostic (7.96e-2)" "unprognostic (2.44e-4)" "unprognostic (1.66e-2)" "unprognostic (9.69e-2)" "unprognostic (2.15e-1)" "unprognostic (1.35e-1)" "unprognostic (5.11e-1)" "unprognostic (4.71e-2)" "unprognostic (7.92e-2)" "unprognostic (3.58e-1)" "unprognostic (1.08e-2)" "unprognostic (2.15e-1)" "unprognostic (1.08e-4)" "unprognostic (1.83e-1)" "unprognostic (1.20e-1)" "unprognostic (2.24e-1)" "unprognostic (2.18e-2)" 0.1 0.2 0.2 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 4.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.3 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.3 8.4 0.0 0.5 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.9 0.0 0.0 1.8 0.0 0.4 0.1 0.3 0.0 0.2 11.6 0.3 0.2 1.0 1.2 0.0 2.6 0.4 0.8 0.3 0.0 0.5 5.7 0.1 0.7 0.4 111.8 0.0 1.8 0.1 0.0 60.5 3.7 18.7 0.3 34.4 1.8 0.0 1.9 0.0 0.0 0.5 0.2 0.1 1.4 0.0 0.1 0.2 0.0 0.7 0.0 0.0 6.6 0.2 0.7 9.4 7.4 0.0 0.1 0.5 0.2 0.1 0.2 0.2 OTOG "FLJ46346, mlemp, OTGN" ENSG00000188162 Otogelin Q6ZRI0 11 17547259-17647150 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "pituitary gland: 1.4" "Group enriched" "Detected in some" 5 "Early spermatids: 11.9;Late spermatids: 28.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "CACO-2: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.25e-2)" "unprognostic (1.19e-1)" "unprognostic (6.95e-3)" "unprognostic (1.85e-6)" "unprognostic (1.89e-1)" "unprognostic (3.60e-1)" "unprognostic (5.14e-5)" "unprognostic (1.78e-1)" "unprognostic (8.97e-2)" "unprognostic (1.57e-2)" "unprognostic (4.72e-5)" "unprognostic (5.55e-2)" "unprognostic (1.48e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 OTOGL "C12orf64, FLJ90579" ENSG00000165899 "Otogelin like" Q3ZCN5 12 80099537-80380880 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 1.9;kidney: 5.1" "Group enriched" "Detected in some" 5 "Excitatory neurons: 51.2;Oligodendrocyte precursor cells: 42.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.3;U-87 MG: 2.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "basal ganglia: 4.2" "HPA040364, HPA053392" Uncertain Approved Cytosol "Secreted in other tissues" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA040364: AB_10795365, HPA053392: AB_2682135" "unprognostic (2.43e-1)" "unprognostic (2.78e-2)" "unprognostic (2.55e-2)" "unprognostic (1.50e-1)" "unprognostic (5.99e-2)" "unprognostic (3.10e-1)" "unprognostic (3.34e-3)" "unprognostic (4.76e-2)" "unprognostic (2.72e-2)" "unprognostic (4.52e-2)" "unprognostic (2.79e-2)" "unprognostic (1.57e-1)" "unprognostic (1.95e-5)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (2.79e-2)" "unprognostic (2.04e-2)" 0.1 0.0 0.5 0.0 0.7 0.0 0.1 0.0 1.0 0.1 0.0 0.4 0.0 0.1 0.1 0.1 0.1 0.1 1.9 0.3 0.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.5 0.1 0.1 0.1 0.5 0.0 0.1 0.4 0.0 0.1 0.2 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.3 0.0 0.0 2.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 1.4 0.1 0.1 0.2 0.0 0.0 51.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.9 0.0 0.0 0.0 42.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 OTOL1 "C1QTNF15, C1QTNF16" ENSG00000182447 "Otolin 1" A6NHN0 3 161496808-161503942 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041030 Uncertain "Secreted in other tissues" NA NA "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA041030: AB_10795000" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 OTOR "FDP, MIAL, MIAL1" ENSG00000125879 Otoraplin Q9NRC9 20 16748358-16770062 "Predicted secreted proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 12.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA024335 Uncertain "Secreted in other tissues" NA NA "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA024335: AB_1854838" "unprognostic (8.50e-3)" "unprognostic (9.56e-2)" "unprognostic (2.34e-1)" "unprognostic (1.81e-1)" "unprognostic (1.72e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 12.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OTOS OTOSP ENSG00000178602 Otospiralin Q8NHW6 2 240139026-240144562 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 103.1;thyroid gland: 43.8" "Cell type enhanced" "Detected in single" "Astrocytes: 1.3" "Cancer enriched" "Detected in some" 4 "thyroid cancer: 28.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (8.52e-2)" "unprognostic (1.73e-1)" "unprognostic (9.01e-3)" "unprognostic (1.35e-1)" "unprognostic (2.72e-1)" "unprognostic (3.27e-3)" 0.0 0.0 10.9 0.0 11.0 0.0 0.1 11.3 11.5 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 14.2 0.3 0.2 0.0 0.0 10.5 11.7 0.0 0.0 0.0 103.1 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 12.7 0.0 43.8 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 11.0 11.3 11.5 11.7 14.2 10.5 11.7 11.2 9.7 12.7 12.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OVCH1 OVCH ENSG00000187950 "Ovochymase 1" Q7RTY7 12 29412474-29497686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 4.5;testis: 2.4" "Group enriched" "Detected in some" 5 "Excitatory neurons: 14.3;Inhibitory neurons: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Daudi: 5.5" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.32e-1)" "unprognostic (2.20e-1)" "unprognostic (2.03e-1)" "unprognostic (1.56e-5)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (4.41e-2)" "unprognostic (1.83e-1)" "unprognostic (2.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.36e-1)" "unprognostic (5.48e-2)" "unprognostic (5.59e-3)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" 0.2 0.2 0.7 0.3 1.2 0.1 0.2 0.0 1.2 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.2 0.9 0.5 0.1 0.2 4.5 0.1 0.0 0.6 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.6 0.1 2.4 0.7 0.0 1.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.0 1.2 0.9 0.5 0.0 0.6 0.1 0.1 0.7 0.5 0.7 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.1 0.7 0.0 0.0 14.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 OVCH2 OVTN ENSG00000183378 "Ovochymase 2" 11 7689437-7706421 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 15 "epididymis: 189.0;retina: 92.2" "Group enriched" "Detected in some" 7 "Collecting duct cells: 7.3;Rod photoreceptor cells: 16.6" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "REH: 25.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.59e-2)" "unprognostic (3.74e-1)" "unprognostic (8.03e-2)" "unprognostic (9.77e-2)" "unprognostic (1.85e-1)" "unprognostic (1.70e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (2.84e-2)" "unprognostic (3.06e-1)" "unprognostic (9.27e-2)" "unprognostic (7.65e-2)" "unprognostic (1.22e-2)" 0.0 0.0 0.1 0.0 0.3 0.4 3.4 0.8 0.2 0.1 0.1 0.0 0.0 0.2 189.0 0.1 0.3 0.0 0.0 0.0 0.1 5.3 0.0 2.4 0.0 0.7 0.4 0.0 0.0 0.0 0.0 1.4 1.0 1.1 0.0 92.2 0.8 5.8 0.4 9.1 0.1 0.0 0.1 0.0 0.5 0.5 0.8 0.0 0.0 0.0 0.1 0.9 0.2 0.7 3.4 0.0 0.3 0.0 0.0 0.0 0.5 0.8 0.6 0.1 0.3 0.2 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 25.2 0.0 0.2 0.2 2.7 0.0 0.2 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.2 0.0 0.1 0.7 0.4 1.0 0.1 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.4 0.1 1.3 0.1 0.0 0.0 7.3 0.0 1.4 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.7 0.0 0.1 0.0 0.7 0.0 16.6 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 OVGP1 "CHIT5, MUC9" ENSG00000085465 "Oviductal glycoprotein 1" Q12889 1 111414319-111427735 "Plasma proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 134 "fallopian tube: 2071.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 9.7;Excitatory neurons: 10.4;Glandular and luminal cells: 12.0;Inhibitory neurons: 8.5;Syncytiotrophoblasts: 17.4" "Group enriched" "Detected in many" 13 "endometrial cancer: 58.7;ovarian cancer: 27.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 4.9;OE19: 6.4;SK-BR-3: 5.0" "Region enhanced" "Detected in many" "cerebellum: 5.9" "Not detected" "Not detected" "HPA031666, HPA062205" Enhanced Supported Vesicles,Microtubules "Secreted in female reproductive system" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles Microtubules "HPA031666: , HPA062205: AB_2684710" "unprognostic (1.52e-1)" "unprognostic (2.06e-2)" "unprognostic (3.35e-2)" "prognostic favorable (1.36e-4)" "unprognostic (8.39e-2)" "unprognostic (3.58e-2)" "unprognostic (2.33e-2)" "unprognostic (3.34e-2)" "unprognostic (5.44e-2)" "unprognostic (3.82e-2)" "unprognostic (7.68e-3)" "unprognostic (2.58e-1)" "unprognostic (5.35e-3)" "unprognostic (2.39e-1)" "unprognostic (1.38e-1)" "unprognostic (3.86e-3)" "prognostic favorable (3.93e-5)" 4.1 1.6 7.6 1.1 7.8 1.9 3.5 8.0 10.6 3.8 5.8 3.4 1.1 15.4 5.1 3.0 2071.7 1.1 2.3 7.7 7.0 5.0 8.0 3.9 2.2 7.3 6.9 6.7 1.5 6.8 2.4 2.0 7.2 5.5 2.2 4.3 4.2 1.5 2.6 7.6 5.2 1.4 6.5 4.6 2.8 9.2 6.9 1.2 2.4 1.0 2.0 4.6 3.8 8.2 0.4 0.4 0.9 0.5 1.8 2.0 1.7 0.2 1.4 0.3 0.7 0.6 0.0 0.8 1.7 0.6 0.0 0.5 0.3 0.3 0.5 2.0 4.9 0.3 0.8 2.4 0.6 0.9 2.2 1.8 2.9 0.0 1.0 1.4 0.4 3.2 0.3 1.5 0.1 0.5 0.6 1.2 0.2 6.4 1.7 0.6 0.2 0.7 1.4 3.7 0.6 0.6 0.1 5.0 0.7 2.4 0.3 0.8 0.8 0.1 0.2 2.5 0.7 1.8 0.5 0.4 0.2 1.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 7.8 8.0 10.6 7.7 7.0 7.3 6.9 7.2 6.5 6.9 8.2 1.2 0.0 1.1 3.3 0.6 3.1 1.1 0.3 0.0 2.1 1.7 1.9 0.6 0.0 0.5 0.0 0.0 5.6 0.2 1.1 1.9 0.2 4.0 9.7 0.7 1.6 0.0 0.0 10.4 0.0 2.6 0.6 0.0 12.0 0.0 1.0 1.4 2.9 0.6 0.0 8.5 1.5 2.0 0.6 1.4 6.1 1.5 0.5 0.0 3.7 0.0 0.4 0.0 1.5 2.4 0.2 0.5 1.9 0.1 1.6 0.6 2.8 1.3 0.6 0.0 0.7 1.1 3.8 0.7 1.0 3.1 17.4 0.8 0.2 1.6 1.6 OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 245.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 243.7;Distal tubular cells: 187.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 238.7;SiHa: 319.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA 440000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" 52.7 15.8 30.4 16.6 34.9 13.3 18.5 23.9 32.7 13.5 15.9 19.2 8.3 14.9 17.6 26.8 12.4 15.2 245.9 36.2 27.1 53.1 1.3 8.0 21.7 19.5 21.4 13.8 5.3 48.6 14.7 5.0 20.0 25.5 21.1 23.6 18.9 29.8 28.5 23.1 12.8 36.6 19.3 11.0 34.2 13.2 25.7 76.8 27.3 42.6 25.9 15.1 13.8 24.5 35.3 1.6 27.9 33.6 84.7 45.0 0.1 62.1 38.9 50.3 30.4 5.7 23.5 91.2 15.0 47.5 25.8 20.5 77.5 55.9 58.5 78.5 9.1 63.9 238.7 11.9 36.8 125.8 20.9 42.7 15.3 49.3 82.2 24.6 46.4 81.6 13.3 114.0 58.1 4.5 105.5 6.1 6.4 0.0 24.5 82.8 78.9 68.7 41.7 2.9 27.9 28.8 319.5 0.3 38.3 2.5 0.4 27.4 28.3 39.7 51.9 68.6 50.6 18.6 16.5 3.6 59.9 90.9 30.9 1.4 1.4 4.7 11.6 1.5 13.8 10.0 11.5 12.7 6.3 7.5 13.6 10.9 0.4 11.3 2.5 2.4 21.5 6.6 30.4 34.9 23.9 32.7 36.2 27.1 19.5 21.4 20.0 19.3 25.7 24.5 8.4 6.4 9.2 37.5 19.2 14.8 11.7 12.4 17.6 14.1 18.8 14.2 243.7 7.2 14.3 11.0 2.1 7.0 18.3 5.0 187.9 5.4 19.1 11.7 18.8 9.8 13.2 23.1 71.5 0.7 11.9 21.3 20.4 31.2 9.5 8.7 6.8 0.3 38.2 13.5 84.2 18.6 12.2 1.3 7.0 8.6 6.2 5.2 16.0 26.2 4.4 11.8 10.3 66.4 46.8 4.8 5.3 7.5 31.3 12.1 2.9 27.4 5.6 21.6 13.1 9.7 24.6 35.6 19.7 27.6 21.6 6.8 26.6 8.6 18.1 9.0 OXCT2 "FKSG25, FLJ00030, SCOT-T" ENSG00000198754 "3-oxoacid CoA-transferase 2" Q9BYC2 1 39769523-39771348 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "testis: 73.0" "Group enriched" "Detected in some" 80 "Early spermatids: 420.5;Late spermatids: 1019.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 7.6;THP-1: 8.4;U-266/70: 6.2" "Not detected" "Not detected" HPA075423 Enhanced NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA075423: AB_2732292" "unprognostic (2.42e-3)" "unprognostic (2.11e-1)" "unprognostic (6.50e-2)" "unprognostic (7.16e-2)" "unprognostic (9.68e-2)" "unprognostic (1.13e-1)" "unprognostic (1.32e-1)" "unprognostic (1.93e-3)" "unprognostic (2.74e-1)" "unprognostic (3.16e-1)" "unprognostic (2.57e-3)" "unprognostic (4.18e-2)" "unprognostic (5.39e-5)" "unprognostic (3.24e-1)" "unprognostic (4.59e-1)" "unprognostic (1.70e-1)" "unprognostic (1.85e-1)" 0.3 0.8 1.1 0.4 1.3 0.5 0.3 1.5 2.0 0.5 0.0 1.0 0.7 1.1 0.9 0.7 0.8 0.7 6.6 1.0 0.5 0.4 0.6 0.5 0.6 1.8 1.1 2.3 1.2 0.1 1.1 0.2 1.8 1.3 0.4 0.0 0.3 1.3 0.4 3.2 1.1 0.6 1.3 1.1 0.7 73.0 1.0 3.9 1.8 0.0 0.2 0.4 0.5 4.5 0.4 0.2 0.0 0.9 0.3 1.1 0.0 1.1 0.0 1.0 0.5 3.9 0.4 0.0 0.7 1.6 0.1 0.4 1.2 0.1 0.5 0.0 2.5 0.7 3.0 0.2 1.8 0.0 0.4 0.5 0.3 0.1 0.1 0.0 0.8 0.3 0.2 7.6 0.1 1.1 0.0 1.2 0.1 0.0 1.0 1.1 1.2 1.2 0.3 0.8 1.3 0.6 3.3 0.2 1.1 0.0 0.4 8.4 0.9 0.0 0.2 3.7 0.0 6.2 3.6 0.4 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 1.3 1.5 2.0 1.0 0.5 1.8 1.1 1.8 1.3 1.0 4.5 0.3 0.0 0.6 0.0 2.3 0.3 0.3 0.1 0.0 0.2 0.3 0.5 3.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.7 420.5 0.2 2.1 0.8 0.0 0.0 0.0 0.7 0.1 1.5 0.0 0.4 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.8 0.0 0.3 8.3 1019.0 4.1 3.0 1.8 0.0 0.7 0.2 0.0 0.0 0.0 0.4 0.1 6.4 8.9 0.5 0.6 0.0 0.1 0.1 0.0 1.1 2.7 3.4 2.7 0.1 0.4 0.0 0.8 0.6 0.5 0.2 OXNAD1 MGC15763 ENSG00000154814 "Oxidoreductase NAD binding domain containing 1" Q96HP4 3 16265160-16350299 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 67.0;Inhibitory neurons: 62.8;T-cells: 90.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 81.0" "Lineage enriched" "Detected in all" 4 "T-cells: 81.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036830, HPA059160" Approved Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "HPA036830: AB_2675338, HPA059160: AB_2683936" "unprognostic (4.49e-2)" "unprognostic (7.41e-3)" "unprognostic (2.71e-3)" "unprognostic (2.38e-3)" "unprognostic (4.65e-2)" "unprognostic (3.23e-2)" "unprognostic (1.46e-1)" "unprognostic (2.31e-2)" "unprognostic (1.23e-2)" "unprognostic (8.05e-2)" "unprognostic (1.46e-1)" "unprognostic (8.08e-2)" "prognostic favorable (1.00e-7)" "unprognostic (2.22e-2)" "unprognostic (1.03e-1)" "unprognostic (6.95e-3)" "prognostic favorable (7.63e-4)" 5.8 4.0 2.0 11.4 3.3 8.9 4.8 2.4 3.7 2.7 3.7 8.5 12.2 3.0 2.5 5.4 3.4 5.0 9.0 1.8 2.4 8.7 16.9 4.2 17.0 2.3 2.4 3.0 3.7 7.3 2.4 3.6 2.5 2.9 7.2 4.6 4.4 2.6 14.9 4.1 14.1 2.8 1.3 7.1 7.3 4.4 2.8 18.1 5.6 10.1 12.1 5.4 3.3 3.4 8.3 12.0 7.6 12.0 8.8 7.8 29.7 8.8 6.5 11.8 9.5 17.2 8.2 11.8 5.4 5.5 6.5 5.9 15.9 14.3 11.2 21.6 10.5 17.4 9.6 9.3 9.1 28.3 10.2 5.8 10.5 19.2 9.2 3.7 9.3 12.0 24.1 27.3 5.2 14.7 16.6 14.8 16.3 12.4 13.8 14.6 9.3 20.7 8.0 9.9 5.4 7.5 9.8 16.3 14.0 8.2 10.4 16.1 4.2 7.7 9.8 8.5 14.4 9.9 19.0 19.0 9.1 24.3 10.5 0.1 3.8 3.1 22.6 5.4 30.3 5.5 34.6 24.5 6.0 4.3 81.0 61.8 3.4 19.3 5.4 4.6 20.4 19.3 2.0 3.3 2.4 3.7 1.8 2.4 2.3 2.4 2.5 1.3 2.8 3.4 4.9 0.0 8.6 35.6 8.9 2.4 5.4 7.9 6.2 5.8 5.7 3.4 12.8 7.2 4.7 7.3 6.2 10.2 29.4 8.9 31.3 9.8 40.2 3.9 5.5 4.4 3.0 16.2 67.0 6.2 8.1 5.1 11.2 3.9 20.8 5.8 3.9 23.3 8.5 3.3 62.8 7.6 6.1 5.2 3.6 31.7 3.1 6.3 5.4 17.8 10.2 5.8 41.2 36.2 42.1 7.5 2.9 1.9 20.8 5.0 21.2 15.7 7.2 11.7 6.6 6.1 6.8 9.0 11.7 7.5 3.4 5.1 90.0 7.8 11.5 6.5 OXT "OT, OT-NPI, OXT-NPI" ENSG00000101405 "Oxytocin/neurophysin I prepropeptide" P01178 20 3071620-3072517 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 60 "brain: 1167.9" "Cell type enhanced" "Detected in many" "Early spermatids: 30.0;Hepatocytes: 41.2;Late spermatids: 66.3;Proximal enterocytes: 15.7;Proximal tubular cells: 36.5" "Cancer enriched" "Detected in some" 5 "testis cancer: 12.1" "Region enriched" "Detected in many" 141 "hypothalamus: 1167.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;HMC-1: 1.1" "Region enriched" "Detected in many" 6 "hypothalamus: 179.3" "Group enriched" "Detected in some" 903 "basal ganglia: 794.6;hypothalamus: 1854.1" HPA071892 Supported Supported "Secreted to blood" NA NA 1500000 "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA071892: AB_2732190" "unprognostic (7.45e-3)" "unprognostic (1.99e-2)" "unprognostic (2.66e-2)" "unprognostic (2.28e-1)" "unprognostic (2.62e-1)" "unprognostic (3.82e-2)" "unprognostic (8.22e-2)" "unprognostic (8.36e-2)" "unprognostic (6.02e-2)" "unprognostic (3.05e-2)" "unprognostic (6.65e-2)" "unprognostic (6.18e-1)" "unprognostic (3.81e-1)" "unprognostic (3.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" 3.2 1.7 8.3 0.0 0.8 0.1 1.7 0.5 0.9 0.9 0.7 0.4 1.0 0.4 0.0 0.2 0.3 0.0 0.5 0.2 1167.9 4.1 19.3 0.2 0.1 0.2 0.7 0.3 0.1 0.0 15.9 0.0 0.2 0.7 0.0 0.0 0.5 0.1 0.2 2.3 1.0 0.0 1.3 0.2 0.2 2.6 7.8 0.0 0.6 0.0 0.0 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.4 0.4 0.2 0.5 2.1 0.8 0.5 0.4 1.6 1.4 1.7 0.5 0.2 0.0 0.7 1.3 0.3 8.3 0.8 0.5 0.9 0.2 1167.9 0.2 0.7 0.2 1.3 7.8 0.2 0.6 0.0 1.8 0.3 3.5 0.8 0.7 0.1 1.2 0.0 1.2 1.7 0.2 0.0 1.3 5.5 0.0 0.0 2.3 0.1 1.9 0.1 30.0 0.2 2.4 0.3 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.5 0.0 0.3 0.0 41.2 0.2 0.0 0.1 1.8 0.0 0.3 1.6 66.3 0.9 0.6 3.6 0.0 0.0 0.0 1.0 0.5 0.0 0.2 1.7 1.2 1.2 0.4 15.7 36.5 0.9 0.0 0.0 1.8 0.7 1.1 7.8 0.3 1.0 0.0 1.1 0.0 2.0 0.3 P2RY8 P2Y8 ENSG00000182162 "P2Y receptor family member 8" Q86VZ1 X 1462581-1537185 "Cancer-related genes, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 31.2;lymphoid tissue: 40.1" "Group enriched" "Detected in some" 4 "B-cells: 42.0;dendritic cells: 56.2;monocytes: 26.1;NK-cells: 56.7;Plasma cells: 49.3;T-cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 119.2;MOLT-4: 60.6;NB-4: 59.6;RPMI-8226: 74.3;THP-1: 73.7;U-266/70: 96.8;U-698: 192.8;U-937: 60.6" "Low region specificity" "Detected in single" HPA003631 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA003631: AB_1079543" "unprognostic (4.32e-2)" "unprognostic (3.22e-5)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.80e-5)" "prognostic favorable (1.73e-4)" "unprognostic (5.27e-3)" "unprognostic (5.76e-3)" "unprognostic (5.52e-3)" "prognostic favorable (6.54e-4)" "unprognostic (4.29e-2)" "unprognostic (8.45e-3)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.80e-1)" 3.5 4.6 0.4 19.2 0.5 31.2 2.4 0.8 1.1 0.7 0.8 3.4 3.4 0.8 0.9 1.3 0.7 3.8 4.9 0.2 0.7 3.6 1.9 3.0 40.1 1.5 0.5 1.1 2.1 2.1 2.1 1.2 0.9 1.5 3.2 0.7 3.4 1.1 2.6 1.8 7.5 1.4 0.5 20.0 5.1 0.4 1.4 16.4 7.9 1.4 33.4 4.4 0.5 1.8 0.6 0.5 0.5 1.5 0.0 0.0 1.3 0.2 0.1 0.0 0.1 0.4 0.7 119.2 0.6 0.0 0.5 0.5 0.0 0.1 0.0 4.7 0.4 1.0 1.3 6.1 0.1 53.2 12.3 0.1 0.1 0.1 0.0 1.1 0.0 35.1 1.1 48.9 0.1 0.1 60.6 59.6 0.7 0.1 1.3 54.1 0.6 74.3 0.1 0.9 0.2 0.8 0.4 1.1 0.3 1.1 0.6 73.7 0.3 1.0 1.1 0.5 0.3 96.8 19.6 192.8 0.2 60.6 0.2 49.9 18.9 31.1 58.6 12.7 53.6 34.2 44.5 55.8 13.6 38.3 34.7 36.4 11.3 37.5 5.2 3.6 37.6 53.3 0.4 0.5 0.8 1.1 0.2 0.7 1.5 0.5 0.9 0.5 1.4 1.8 5.9 0.0 1.8 0.3 42.0 0.4 0.0 0.0 0.0 0.7 0.3 0.0 1.2 0.0 0.6 1.8 0.0 0.0 56.2 0.1 0.0 0.0 0.0 0.1 0.1 5.2 0.0 9.9 0.7 0.2 0.0 0.4 2.6 0.1 1.3 0.3 3.9 0.3 1.9 0.0 0.7 0.0 0.0 11.2 1.8 0.0 0.0 8.7 1.8 1.9 26.1 0.0 56.7 1.0 0.4 0.0 0.0 0.0 49.3 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.0 0.4 0.0 40.7 0.9 0.2 0.0 P3H1 "GROS1, LEPRE1, LEPRECAN, MGC117314" ENSG00000117385 "Prolyl 3-hydroxylase 1" Q32P28 1 42746335-42767084 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Extravillous trophoblasts: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 193.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012113, HPA016980" Approved Approved Nucleoli,Vesicles "Intracellular and membrane" NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles Nucleoli "HPA012113: AB_2668626, HPA016980: AB_2669498" "unprognostic (3.24e-1)" "unprognostic (1.04e-1)" "unprognostic (9.37e-2)" "unprognostic (4.57e-1)" "unprognostic (2.03e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.95e-7)" "unprognostic (5.41e-2)" "unprognostic (2.70e-3)" "unprognostic (9.16e-2)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" "unprognostic (2.67e-2)" "unprognostic (1.60e-3)" 12.4 11.1 3.6 8.7 3.5 6.1 10.2 3.6 4.4 13.4 7.3 8.3 2.4 13.8 6.1 4.4 9.8 12.0 9.1 3.8 3.8 7.2 13.3 11.6 5.1 5.2 3.5 12.8 6.8 5.9 15.5 37.4 3.8 7.5 5.4 1.3 6.7 5.9 3.0 7.6 7.4 20.3 3.4 11.5 6.7 15.2 3.8 7.6 7.6 3.9 5.1 12.3 8.5 3.6 8.7 22.3 48.7 115.0 112.8 85.4 20.1 101.8 131.9 71.9 121.7 11.3 18.8 13.0 79.7 193.0 29.2 7.8 20.9 25.9 49.2 19.5 26.3 30.5 32.2 32.6 65.2 30.9 34.0 73.8 17.4 72.6 30.9 102.4 102.9 18.3 17.5 16.1 49.0 4.7 20.6 17.8 53.1 4.7 16.0 19.9 71.9 17.7 38.2 4.9 10.2 17.3 62.5 1.7 45.8 85.2 3.7 127.0 85.1 53.8 47.2 43.4 41.2 14.5 17.5 11.9 61.5 41.5 77.0 5.0 18.9 16.8 8.3 20.4 8.8 4.1 6.3 7.0 23.6 3.3 5.1 5.3 1.8 17.8 26.3 10.9 12.4 9.3 3.6 3.5 3.6 4.4 3.8 3.8 5.2 3.5 3.8 3.4 3.8 3.6 13.7 3.2 2.3 5.9 10.5 0.0 6.4 0.0 6.2 10.2 4.5 6.5 5.0 7.2 0.6 11.0 25.0 47.9 11.1 0.4 0.0 11.5 17.1 3.2 30.1 16.4 6.1 11.3 12.9 7.6 56.6 34.4 3.6 4.4 1.3 28.8 16.8 11.3 17.6 15.2 10.8 2.5 0.0 8.7 0.0 10.8 19.3 11.7 0.0 9.4 10.5 3.5 6.2 9.5 6.9 7.4 2.0 16.1 11.2 3.4 1.7 1.9 0.7 22.1 0.0 17.2 22.3 30.6 18.8 3.5 0.0 17.5 9.6 27.0 1.9 4.5 P3H2 "FLJ10718, LEPREL1, MLAT4" ENSG00000090530 "Prolyl 3-hydroxylase 2" Q8IVL5 3 189956728-190122437 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 80.3;Granulosa cells: 124.1;Microglial cells: 91.8;Theca cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "plasmacytoid DC: 28.9" "Lineage enriched" "Detected in single" 90 "dendritic cells: 28.9" "Cell line enhanced" "Detected in many" "GAMG: 120.2;HaCaT: 109.9;RPTEC TERT1: 109.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007890, HPA013355, HPA013611" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "Nucleoplasm, Vesicles, Cytosol" "HPA007890: AB_1852796, HPA013355: AB_1852798, HPA013611: " "unprognostic (4.90e-2)" "unprognostic (1.57e-1)" "unprognostic (3.76e-1)" "unprognostic (4.32e-3)" "unprognostic (1.97e-2)" "unprognostic (7.75e-2)" "unprognostic (9.68e-2)" "unprognostic (2.17e-1)" "unprognostic (3.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.03e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-2)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.10e-1)" "unprognostic (4.01e-2)" 4.9 41.6 2.8 4.9 3.1 1.0 6.5 3.0 3.1 17.0 1.8 24.0 2.7 17.6 18.5 11.0 8.0 4.8 8.8 3.3 4.8 51.3 7.0 28.7 2.4 7.6 4.7 16.1 3.6 2.3 8.2 9.2 6.7 37.6 10.4 19.3 4.9 26.5 1.2 17.8 6.7 32.4 5.2 54.8 23.9 4.2 4.9 5.2 3.0 1.7 2.0 11.9 19.9 8.3 46.9 18.2 35.1 0.2 0.6 1.4 42.1 48.7 19.3 7.8 12.6 15.0 18.0 0.1 27.1 8.6 120.2 109.9 0.1 65.3 16.3 0.4 6.2 0.1 12.1 0.3 35.4 0.2 0.3 16.9 21.4 15.2 5.4 73.5 1.4 0.1 0.1 0.4 12.3 1.1 0.1 0.4 11.0 31.3 3.7 0.1 7.1 2.8 109.8 77.5 2.5 0.3 66.1 3.7 29.3 51.1 0.1 0.7 24.4 45.9 16.8 0.4 8.9 3.4 0.2 0.5 10.6 0.2 60.2 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.1 0.0 28.9 0.0 0.2 2.8 3.1 3.0 3.1 3.3 4.8 7.6 4.7 6.7 5.2 4.9 8.3 5.7 48.1 80.3 19.2 1.0 0.0 7.7 0.0 13.6 2.3 1.6 9.9 1.0 2.8 3.1 44.1 4.2 42.0 9.5 19.8 5.9 4.7 19.6 2.0 27.3 10.5 0.0 2.7 55.6 0.8 14.7 10.3 8.6 1.5 1.3 124.1 32.5 0.8 11.4 10.1 60.4 0.5 0.0 3.2 0.0 14.9 4.7 5.6 0.0 91.8 0.8 44.5 0.0 43.7 4.4 30.6 1.9 0.0 0.2 15.1 0.0 26.2 0.0 1.2 0.0 10.9 45.2 0.5 0.9 13.5 0.0 38.6 0.7 74.3 2.1 3.9 P3H3 "GRCB, HSU47926, LEPREL2" ENSG00000110811 "Prolyl 3-hydroxylase 3" Q8IVL6 12 6828407-6839847 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 19.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 47.2;Cone photoreceptor cells: 100.1;Horizontal cells: 43.7;Leydig cells: 49.7;Peritubular cells: 38.4;Rod photoreceptor cells: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 39.6;hTERT-RPE1: 27.3;NTERA-2: 27.5;U-251 MG: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043695 Approved Approved "Nucleoli,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 740000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Nucleoli "HPA043695: AB_10797146" "unprognostic (2.54e-1)" "unprognostic (6.66e-2)" "unprognostic (1.14e-1)" "unprognostic (3.34e-2)" "unprognostic (5.76e-2)" "unprognostic (6.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.92e-1)" "unprognostic (6.90e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.64e-4)" "unprognostic (2.58e-2)" "unprognostic (9.67e-2)" "unprognostic (2.27e-1)" "unprognostic (7.77e-3)" 3.5 2.6 1.2 1.5 0.7 0.3 3.9 3.7 2.7 11.9 5.6 5.4 0.8 19.2 0.5 1.6 9.9 1.7 4.5 1.1 1.2 2.0 0.6 3.7 0.3 1.3 0.2 12.4 2.9 4.5 15.4 1.3 0.3 6.0 0.3 4.1 6.5 3.7 0.8 3.0 2.8 3.8 0.2 1.3 3.8 1.2 0.9 0.1 4.3 0.3 0.3 7.8 6.4 0.5 0.0 1.6 7.1 14.0 8.4 10.2 0.3 39.6 22.4 12.2 13.5 0.6 0.0 0.0 0.5 14.9 0.5 0.0 4.4 0.4 2.7 0.1 18.8 1.0 4.2 1.9 5.9 1.0 0.0 11.1 0.4 6.0 3.3 27.3 13.1 1.2 3.7 0.0 5.7 0.0 0.1 0.4 27.5 0.0 1.1 0.0 6.9 0.2 0.6 0.0 2.8 10.5 0.1 0.0 4.8 3.4 0.2 0.2 23.2 12.0 17.5 18.6 27.7 0.1 0.3 0.3 10.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 3.7 2.7 1.1 1.2 1.3 0.2 0.3 0.2 0.9 0.5 2.3 0.0 0.0 3.3 0.5 0.0 4.9 0.0 2.2 47.2 5.3 5.5 11.1 1.5 1.8 5.5 100.1 0.5 0.1 0.1 1.9 1.4 0.9 0.9 19.6 3.9 1.2 0.0 13.1 2.7 0.5 24.1 2.0 0.4 0.0 0.8 7.9 0.0 1.4 43.7 13.7 2.7 0.0 0.0 0.0 2.2 49.7 0.5 0.0 2.8 1.1 5.3 0.0 5.5 1.3 1.3 0.1 38.4 3.1 5.1 0.4 0.4 1.5 28.8 6.6 7.8 11.9 0.7 0.8 0.8 0.0 1.0 0.9 3.2 0.6 1.5 P3H4 "LEPREL4, NO55, SC65" ENSG00000141696 "Prolyl 3-hydroxylase family member 4 (inactive)" Q92791 17 41801947-41812604 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 3.9;MAIT T-cell: 5.0;memory CD4 T-cell: 2.5;memory CD8 T-cell: 2.7;naive CD4 T-cell: 3.0;naive CD8 T-cell: 3.9;NK-cell: 8.5" "Group enriched" "Detected in many" 10 "NK-cells: 8.5;T-cells: 5.0" "Cell line enriched" "Detected in many" 13 "OE19: 1032.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022520 Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum, Vesicles" "HPA022520: " "unprognostic (9.11e-2)" "unprognostic (3.72e-3)" "unprognostic (3.66e-2)" "unprognostic (3.72e-2)" "unprognostic (8.69e-3)" "unprognostic (4.32e-2)" "unprognostic (2.16e-3)" "unprognostic (1.94e-1)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (4.03e-2)" "prognostic unfavorable (4.48e-6)" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (8.96e-2)" "unprognostic (1.96e-3)" 5.1 11.6 5.4 5.5 5.6 0.5 4.9 7.3 6.6 10.0 7.5 6.2 7.6 10.7 4.9 2.8 7.7 6.8 8.8 4.6 6.8 7.8 2.3 6.0 2.7 5.2 4.9 7.9 12.9 11.5 10.5 12.1 4.9 7.3 4.2 1.3 10.4 7.2 4.8 7.4 6.5 10.1 4.5 3.3 5.2 2.3 6.6 1.3 12.2 2.0 1.6 7.2 6.4 4.5 9.2 45.0 27.4 70.8 29.1 28.1 26.9 75.5 33.6 25.6 35.0 22.3 12.4 1.4 30.6 58.7 19.5 16.4 23.6 32.3 10.1 21.0 35.5 11.4 44.1 30.3 35.4 2.3 3.6 29.5 9.5 22.3 20.3 61.0 32.6 3.2 2.2 11.6 16.7 31.6 0.6 6.8 17.1 1032.2 25.2 25.3 30.1 31.4 16.5 2.7 13.2 29.0 13.3 81.2 28.9 18.1 46.8 7.4 34.3 24.5 35.7 46.2 34.1 10.7 2.6 0.2 37.7 11.1 38.5 0.0 0.2 0.0 3.9 0.0 5.0 0.6 2.5 2.7 0.2 0.6 3.0 3.9 0.0 8.5 0.0 0.0 0.7 1.5 5.4 5.6 7.3 6.6 4.6 6.8 5.2 4.9 4.9 4.5 6.6 4.5 7.3 0.0 7.8 12.1 1.5 0.0 5.4 0.0 6.2 3.6 11.6 10.8 10.7 11.5 1.8 5.5 8.4 10.8 3.6 7.2 7.9 21.6 0.5 2.7 25.3 11.0 2.4 7.0 6.4 6.5 27.3 26.6 16.8 7.7 1.3 17.7 11.0 1.9 2.8 26.9 4.4 13.0 0.0 1.2 0.0 0.8 21.1 1.0 0.0 4.7 1.2 9.6 13.4 6.0 1.5 7.1 9.5 20.7 2.8 9.6 26.8 5.9 0.7 2.7 19.7 13.1 16.7 2.7 10.0 1.9 0.0 5.3 3.2 19.1 9.8 2.0 P4HA2 C-P4Halpha(II) ENSG00000072682 "Prolyl 4-hydroxylase subunit alpha 2" O15460 5 132190147-132295315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 115.6;Endometrial stromal cells: 96.9;Skeletal myocytes: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HHSteC: 324.2;U-87 MG: 323.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA016997, HPA027824, CAB062557" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" No No 13000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum, Vesicles" "CAB062557: AB_2665641, HPA016997: AB_2669501, HPA027824: AB_2672402" "unprognostic (1.30e-3)" "prognostic unfavorable (1.24e-5)" "unprognostic (2.56e-3)" "unprognostic (1.28e-3)" "unprognostic (2.08e-3)" "unprognostic (1.62e-3)" "unprognostic (1.16e-3)" "unprognostic (1.93e-3)" "unprognostic (2.83e-2)" "unprognostic (1.92e-1)" "unprognostic (8.98e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (2.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.12e-4)" 17.4 11.7 11.9 16.1 12.1 2.4 12.3 11.4 28.4 29.5 42.2 28.7 22.6 31.1 76.7 19.6 29.6 19.9 40.6 14.4 17.2 80.0 10.5 31.5 2.5 11.4 14.3 8.6 70.7 10.9 19.9 35.1 19.1 10.8 32.7 7.8 32.5 17.1 13.0 16.7 26.8 52.6 10.0 8.7 20.5 9.7 16.8 11.3 20.7 22.9 8.3 22.9 22.3 12.2 57.0 34.9 11.2 57.2 149.2 173.7 61.1 261.9 223.7 108.9 265.0 78.9 50.3 1.5 71.8 283.3 120.5 70.2 33.2 136.5 172.7 41.5 11.9 0.6 48.1 49.0 324.2 0.0 33.9 104.6 193.1 128.8 117.4 162.7 59.1 0.1 21.2 3.6 134.0 23.2 0.2 0.5 3.0 53.7 27.2 0.9 3.6 9.8 31.1 11.0 5.4 15.8 67.7 22.3 47.9 84.1 28.4 3.7 88.9 171.7 63.5 51.0 57.1 24.4 28.1 11.8 323.4 0.4 48.3 0.0 0.4 0.0 0.8 0.3 0.7 0.0 0.4 0.1 0.2 0.0 0.0 0.1 1.0 0.9 0.0 0.3 0.0 0.2 11.9 12.1 11.4 28.4 14.4 17.2 11.4 14.3 19.1 10.0 16.8 12.2 13.0 35.3 10.3 7.5 1.1 16.8 43.6 115.6 23.9 11.6 9.5 9.5 13.3 8.6 36.9 11.0 22.9 2.6 0.3 43.2 5.9 68.3 1.4 26.7 96.9 12.2 15.0 0.0 7.7 71.8 70.2 61.6 12.8 28.0 5.7 11.1 9.3 7.8 7.6 0.0 7.7 18.6 32.6 1.3 5.5 2.0 8.1 4.4 30.2 2.8 2.6 6.8 0.0 1.5 1.2 81.9 41.0 5.3 3.0 19.6 41.4 44.6 71.9 5.2 26.3 109.4 47.6 23.0 29.1 6.8 9.8 7.5 4.8 10.4 13.8 15.3 P4HA3 C-P4Halpha(III) ENSG00000149380 "Prolyl 4-hydroxylase subunit alpha 3" Q7Z4N8 11 74235801-74311640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 10.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Early spermatids: 25.6;Erythroid cells: 13.5;Horizontal cells: 18.5;Rod photoreceptor cells: 12.8;Spermatocytes: 13.1;Spermatogonia: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 19.5;fHDF/TERT166: 9.5;HSkMC: 9.1;HUVEC TERT2: 38.2;TIME: 27.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA007897 Approved "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA007897: AB_2156427" "unprognostic (2.74e-2)" "unprognostic (1.37e-4)" "unprognostic (1.31e-3)" "unprognostic (3.19e-2)" "unprognostic (2.54e-4)" "unprognostic (9.65e-3)" "unprognostic (4.34e-2)" "unprognostic (3.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.21e-3)" "unprognostic (1.38e-2)" "unprognostic (8.31e-2)" "prognostic unfavorable (3.34e-9)" "unprognostic (1.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (7.83e-4)" 1.6 0.7 0.1 3.9 0.0 0.0 0.9 0.1 0.3 1.3 0.3 1.6 0.3 4.5 0.5 0.3 1.2 5.6 0.3 0.0 0.1 1.0 1.3 1.4 0.9 0.1 0.1 1.0 0.2 0.0 3.7 3.9 0.1 6.3 0.7 0.0 0.5 4.3 0.1 0.3 0.4 10.5 0.0 0.1 0.4 1.5 0.1 0.1 2.6 0.1 0.3 5.4 1.7 0.1 0.0 1.4 1.7 0.0 6.2 0.7 0.0 19.5 1.4 1.0 2.1 0.0 0.0 0.0 1.8 9.5 0.7 0.0 0.0 0.3 0.2 0.0 0.1 0.0 1.2 0.0 8.0 0.0 0.0 9.1 0.0 6.5 0.7 1.1 38.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 27.4 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.2 0.4 0.7 0.9 0.0 9.1 0.5 0.1 0.4 0.0 0.2 0.0 14.6 0.2 3.1 0.2 0.0 0.2 25.6 3.8 2.5 3.2 0.0 13.5 2.4 0.0 0.4 5.2 0.0 1.0 0.0 4.3 6.1 0.0 0.4 18.5 3.3 0.2 0.0 0.9 1.1 3.2 0.0 0.3 0.0 6.5 1.6 1.9 3.1 1.5 0.9 0.8 0.2 0.4 0.0 1.1 0.2 0.0 0.7 12.8 0.0 2.1 5.4 13.1 12.2 0.1 0.3 0.1 0.4 1.3 0.2 0.6 P4HB "DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB" ENSG00000185624 "Prolyl 4-hydroxylase subunit beta" P07237 17 81843159-81860856 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chaperone, Isomerase" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1856.8;pancreas: 2446.9" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 1077.9;Extravillous trophoblasts: 1349.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012463, HPA018884" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No No 110000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB012463: , HPA018884: AB_1854896" "unprognostic (9.47e-3)" "unprognostic (1.09e-2)" "unprognostic (2.99e-2)" "unprognostic (7.14e-3)" "unprognostic (7.75e-3)" "unprognostic (1.05e-2)" "unprognostic (1.30e-1)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (4.73e-3)" "unprognostic (1.43e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (2.30e-11)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (4.99e-3)" "unprognostic (3.19e-3)" 266.5 507.8 34.6 209.8 35.7 517.1 225.5 39.1 35.7 272.0 59.6 258.4 640.2 206.5 133.0 618.7 183.4 202.0 318.4 31.7 50.2 270.7 1856.8 301.3 104.0 48.9 37.1 187.8 2446.9 144.3 330.0 334.3 40.8 335.8 173.6 23.3 948.1 184.2 328.5 370.4 554.7 179.8 39.8 428.6 539.2 68.8 58.7 89.3 244.8 150.8 137.9 233.7 322.9 43.7 690.3 580.7 236.8 687.5 813.4 726.7 593.6 1038.5 1081.1 741.9 934.5 550.4 576.9 264.4 501.8 1120.2 407.5 464.1 248.8 647.4 254.1 145.8 320.5 355.2 362.9 953.6 1010.8 1146.4 613.4 618.8 494.8 478.2 596.7 843.0 1250.1 182.1 273.6 978.2 559.5 566.4 260.5 723.2 157.7 791.0 463.8 261.8 342.5 614.0 453.2 492.8 248.7 301.1 586.1 1693.1 808.1 289.6 855.3 1601.2 644.1 980.5 503.1 574.3 586.6 743.5 407.9 204.8 1372.0 591.3 825.4 198.3 268.1 163.0 202.6 154.4 209.8 83.9 138.9 165.7 174.7 68.1 74.9 114.6 72.9 157.0 115.3 311.5 105.6 372.4 34.6 35.7 39.1 35.7 31.7 50.2 48.9 37.1 40.8 39.8 58.7 43.7 122.3 102.5 162.1 23.2 151.4 120.1 163.6 371.0 140.6 59.2 283.0 170.8 24.1 247.4 211.7 112.2 33.3 790.2 208.9 420.7 41.1 671.9 43.5 78.4 196.8 153.9 199.9 140.9 15.3 1077.9 1349.1 272.5 388.9 209.1 99.1 210.4 190.2 840.7 435.9 62.2 16.2 610.9 189.2 186.9 125.5 64.9 141.4 180.3 136.9 20.6 263.3 122.7 230.7 13.6 19.6 575.2 465.6 112.1 664.3 310.6 914.2 105.0 91.3 54.3 157.8 103.4 226.7 83.4 94.1 302.3 144.6 1001.2 138.8 378.4 475.4 220.8 P4HTM "EGLN4, FLJ20262, HIFPH4, P4H-TM, PH-4, PH4, PHD4" ENSG00000178467 "Prolyl 4-hydroxylase, transmembrane" Q9NXG6 3 48989889-49007153 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 155.3;Respiratory ciliated cells: 169.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007199 Supported Uncertain Vesicles,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Cytosol" "HPA007199: AB_1855272" "unprognostic (1.95e-2)" "unprognostic (3.12e-2)" "unprognostic (9.47e-2)" "prognostic favorable (8.18e-4)" "unprognostic (7.78e-2)" "unprognostic (1.05e-1)" "unprognostic (6.47e-2)" "unprognostic (2.02e-2)" "unprognostic (1.89e-2)" "unprognostic (3.78e-2)" "unprognostic (2.51e-3)" "unprognostic (1.54e-2)" "prognostic favorable (3.28e-5)" "unprognostic (1.10e-2)" "unprognostic (3.51e-1)" "unprognostic (2.60e-2)" "unprognostic (9.65e-3)" 13.3 37.1 50.6 4.9 53.3 5.9 12.4 44.3 67.9 18.4 89.7 14.7 12.1 17.6 18.7 8.2 39.8 11.2 26.2 53.5 57.3 29.8 11.9 15.7 6.5 52.2 49.6 20.0 38.5 39.4 75.9 11.0 51.5 18.5 7.4 16.4 19.6 16.8 15.2 10.1 13.0 7.4 45.8 10.7 25.1 23.6 53.3 5.5 26.5 11.3 3.8 12.8 13.1 49.6 8.6 27.9 4.8 0.1 15.5 17.6 0.4 16.8 24.6 13.2 14.8 6.3 55.6 8.1 15.8 21.6 10.5 4.8 12.5 6.6 4.1 30.4 19.5 0.0 42.1 0.0 38.6 8.3 0.2 11.0 6.3 13.4 1.1 51.4 15.0 0.1 0.0 37.9 6.5 48.1 1.2 1.0 6.8 52.6 31.2 0.0 0.0 53.5 24.4 15.9 20.9 0.2 17.7 25.0 0.1 1.1 20.1 13.1 9.9 8.0 6.1 19.9 14.5 50.0 28.6 0.1 54.9 0.7 7.1 8.0 9.0 5.9 6.7 3.5 9.6 8.4 12.3 11.7 9.4 15.9 13.0 8.3 0.8 5.9 4.5 1.6 17.0 6.0 50.6 53.3 44.3 67.9 53.5 57.3 52.2 49.6 51.5 45.8 53.3 49.6 15.1 22.4 17.3 36.2 16.1 9.2 34.6 41.1 12.5 72.9 28.7 23.0 12.0 41.5 44.0 46.0 87.6 31.4 13.4 27.4 19.6 38.3 138.4 106.4 23.7 12.6 80.9 12.4 55.7 39.1 9.9 28.1 48.9 31.2 22.9 31.6 15.4 8.5 16.8 117.8 48.6 40.4 65.1 6.3 12.8 155.3 30.4 13.0 12.4 20.6 11.3 58.4 14.4 17.1 32.3 23.6 51.8 25.9 28.9 24.4 56.2 30.4 169.4 72.5 19.7 32.9 24.7 32.5 7.0 12.9 10.4 26.1 25.0 23.9 40.9 31.2 PABPC1L "C20orf119, dJ1069P2.3, ePAB, PABPC1L1" ENSG00000101104 "Poly(A) binding protein cytoplasmic 1 like" Q4VXU2 20 44910060-44959035 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 24.6;Collecting duct cells: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA066650 Approved "Nuclear bodies,Cytosol" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" Cytosol "Nuclear bodies" "HPA066650: AB_2685698" "unprognostic (4.98e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (3.80e-4)" "unprognostic (1.73e-2)" "unprognostic (2.26e-1)" "unprognostic (2.24e-2)" "unprognostic (1.77e-3)" "unprognostic (4.92e-3)" "unprognostic (3.69e-2)" "unprognostic (2.44e-1)" "unprognostic (2.28e-3)" "unprognostic (7.96e-2)" "prognostic unfavorable (4.00e-15)" "unprognostic (1.01e-1)" "unprognostic (1.88e-1)" "unprognostic (8.63e-2)" "prognostic favorable (8.84e-4)" 2.1 2.3 1.7 2.0 1.8 4.1 2.9 1.1 2.1 4.0 2.5 1.7 0.8 1.5 3.4 2.1 3.4 1.4 1.3 1.7 1.8 6.1 5.9 2.9 3.3 1.4 1.8 6.6 6.1 0.5 6.1 0.6 1.4 5.2 0.6 0.4 2.5 0.9 0.5 2.1 2.9 0.6 1.3 4.4 2.8 1.9 2.5 3.0 7.9 0.1 1.9 1.9 1.9 1.7 2.0 3.4 1.9 4.1 0.4 2.6 8.9 3.7 0.3 1.4 0.4 8.4 3.4 2.2 7.3 0.2 1.2 4.7 0.5 1.3 0.9 1.9 4.0 1.9 8.1 7.2 2.1 1.6 0.5 0.5 6.4 1.2 1.5 1.1 0.0 3.1 3.0 2.2 0.3 8.0 2.8 4.9 1.2 3.0 7.6 3.7 0.6 2.2 0.7 2.6 2.0 3.0 1.6 5.7 6.7 1.8 9.7 1.8 0.2 5.2 5.7 3.4 1.6 5.4 8.8 1.8 1.7 0.8 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.7 1.8 1.1 2.1 1.7 1.8 1.4 1.8 1.4 1.3 2.5 1.7 1.3 6.4 24.6 11.8 7.0 1.9 3.3 3.3 6.2 0.5 7.6 9.9 1.5 7.2 15.6 20.2 0.0 6.7 4.7 2.8 0.0 3.3 0.6 9.5 6.8 1.5 4.2 1.7 5.3 0.5 4.4 4.2 12.8 11.1 3.8 10.3 0.4 5.7 3.0 0.0 2.3 3.0 2.0 0.8 1.6 0.6 1.8 3.3 0.0 1.9 2.3 1.4 3.1 11.1 3.2 1.8 2.4 1.9 5.1 3.5 1.5 1.5 10.1 1.3 0.0 2.1 2.6 0.9 2.1 4.9 1.7 3.8 7.0 2.1 4.4 2.9 PABPC4 "APP-1, iPABP" ENSG00000090621 "Poly(A) binding protein cytoplasmic 4" Q13310 1 39560709-39576790 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 469.7;skeletal muscle: 557.5" "Cell type enhanced" "Detected in all" "Kupffer cells: 460.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027301, HPA056496" Supported Enhanced Cytosol NA NA 850000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Cytosol "HPA027301: AB_2672208, HPA056496: AB_2683153" "unprognostic (6.81e-2)" "unprognostic (7.01e-3)" "unprognostic (2.93e-2)" "unprognostic (5.45e-2)" "unprognostic (3.63e-1)" "unprognostic (1.29e-2)" "prognostic unfavorable (1.14e-7)" "unprognostic (2.22e-1)" "unprognostic (2.62e-1)" "unprognostic (1.12e-1)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (3.00e-10)" "unprognostic (1.87e-1)" "unprognostic (3.18e-1)" "unprognostic (2.91e-1)" "unprognostic (5.08e-1)" 98.4 95.9 26.1 51.2 27.5 76.8 76.1 24.7 28.6 68.8 31.5 83.6 36.8 87.2 41.1 72.1 67.8 39.8 151.9 25.8 24.4 57.0 82.0 72.9 65.1 33.6 25.6 124.8 469.7 27.9 37.4 49.6 30.4 59.3 32.7 22.7 75.5 36.9 557.5 65.0 66.7 46.2 30.4 71.2 153.1 99.4 32.7 32.7 55.0 244.6 65.1 91.9 69.2 36.1 280.8 90.3 75.7 143.3 223.0 441.9 250.7 161.6 135.2 143.5 103.6 175.0 142.2 239.7 150.3 238.5 58.0 131.5 161.2 197.8 175.8 120.6 128.7 200.2 94.1 194.7 234.5 146.5 122.5 392.7 234.3 164.0 252.6 180.0 179.4 174.9 211.3 126.6 231.5 131.5 135.3 132.8 268.9 95.4 98.0 105.4 274.6 194.9 138.4 343.0 63.9 106.9 118.3 106.1 266.1 137.3 115.8 388.9 146.2 118.6 161.8 308.1 201.3 315.1 423.3 202.5 181.7 130.8 78.6 9.8 18.2 4.8 14.2 22.9 13.3 16.0 20.6 13.0 19.0 19.9 25.3 17.6 1.9 11.8 33.0 18.2 14.9 7.9 26.1 27.5 24.7 28.6 25.8 24.4 33.6 25.6 30.4 30.4 32.7 36.1 55.0 19.2 48.9 8.8 120.6 55.8 80.7 36.5 45.5 25.9 104.4 77.5 145.3 90.1 47.7 47.8 81.3 85.2 82.0 115.5 41.1 44.4 70.7 49.0 95.7 50.5 59.3 75.3 9.4 92.3 154.1 69.1 88.7 78.9 53.2 83.0 69.9 152.7 100.5 33.7 10.3 87.5 26.4 460.9 104.6 25.6 69.0 162.4 56.9 13.1 78.6 29.1 30.9 6.0 13.7 57.0 83.2 46.3 212.5 103.5 96.4 46.5 17.5 110.5 6.6 85.3 75.2 37.4 186.3 77.5 41.8 107.1 66.7 86.2 81.7 114.9 PAEP "GD, GdA, GdF, GdS, MGC138509, MGC142288, PAEG, PEP, PP14" ENSG00000122133 "Progestagen associated endometrial protein" P09466 9 135561756-135566955 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 94.1;endometrium 1: 256.0" "Cell type enriched" "Detected in some" 10 "Glandular and luminal cells: 10785.5" "Cancer enriched" "Detected in many" 8 "melanoma: 275.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.1;neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.1" "Cell line enriched" "Detected in some" 7 "SK-MEL-30: 21.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016762, HPA020108, HPA029473" Enhanced "Secreted in female reproductive system" NA NA 120000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "CAB016762: , HPA020108: AB_1855595, HPA029473: AB_10610147" "unprognostic (3.39e-2)" "unprognostic (8.47e-3)" "unprognostic (6.84e-2)" "unprognostic (3.46e-2)" "unprognostic (3.20e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (1.27e-2)" "unprognostic (1.72e-1)" "unprognostic (3.95e-3)" "unprognostic (1.93e-3)" "prognostic unfavorable (0.00e+0)" "prognostic unfavorable (5.46e-4)" "unprognostic (4.24e-1)" "unprognostic (4.98e-2)" 0.1 0.2 0.2 1.1 0.4 1.6 0.5 0.7 0.7 94.1 2.0 0.1 1.0 256.0 0.9 0.2 4.8 0.3 0.1 0.4 0.4 0.1 0.1 0.5 0.6 0.3 0.2 0.7 0.0 0.0 0.0 27.2 0.2 2.7 0.1 0.4 0.4 44.8 0.6 2.1 0.8 0.1 0.1 0.3 6.0 0.7 0.4 0.0 0.3 0.0 0.1 0.3 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.0 0.9 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.6 1.6 2.2 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.2 2.9 0.2 0.0 0.3 0.0 0.7 0.5 0.0 0.0 0.2 0.2 0.3 0.0 0.2 0.4 0.2 0.1 0.2 21.0 0.6 0.3 0.2 0.0 0.0 1.0 0.2 0.1 0.8 2.2 0.1 0.2 0.2 0.2 3.1 0.3 0.2 0.2 0.2 0.1 0.2 0.3 0.2 0.1 0.4 0.3 0.3 1.4 0.3 0.3 0.5 0.1 0.1 0.2 0.4 0.7 0.7 0.4 0.4 0.3 0.2 0.2 0.1 0.4 1.0 0.0 0.0 0.5 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.9 0.6 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 613.5 1008.8 67.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 10785.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 144.0 0.0 0.0 0.0 0.0 0.0 86.5 0.0 0.0 0.0 PAG1 "CBP, PAG" ENSG00000076641 "Phosphoprotein membrane anchor with glycosphingolipid microdomains 1" Q9NWQ8 8 80967810-81112068 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 169.6;granulocytes: 124.5;Melanocytes: 140.5;Microglial cells: 166.8;Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 35.4;HMC-1: 45.5;SK-MEL-30: 36.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001632, HPA066527" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Plasma membrane" "HPA001632: AB_1079557, HPA066527: AB_2685685" "unprognostic (8.30e-2)" "unprognostic (3.84e-2)" "unprognostic (5.89e-2)" "unprognostic (4.79e-2)" "unprognostic (1.55e-1)" "unprognostic (6.91e-2)" "unprognostic (3.71e-3)" "unprognostic (3.84e-2)" "unprognostic (3.73e-2)" "unprognostic (4.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.24e-6)" "unprognostic (2.12e-1)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.80e-1)" "unprognostic (1.94e-3)" 3.9 3.1 3.4 9.0 3.5 12.3 2.0 14.8 4.0 1.8 4.3 9.2 7.6 1.9 2.2 1.6 1.8 7.1 4.7 2.8 3.7 1.7 4.7 14.9 14.5 4.5 4.5 1.2 14.9 0.9 2.0 16.0 4.9 2.6 8.7 5.0 3.7 2.1 1.3 4.3 9.0 3.0 4.9 9.1 4.4 0.7 5.2 10.4 1.8 2.1 14.0 4.8 2.6 5.6 0.1 0.1 4.8 0.2 8.9 8.5 0.1 2.0 15.5 1.0 1.9 0.3 0.1 35.4 0.2 0.5 7.6 1.5 0.1 1.8 0.9 0.9 4.5 20.8 0.3 0.0 9.1 3.4 45.5 4.1 1.2 8.9 8.2 0.9 0.0 6.2 0.2 0.1 14.8 0.3 12.6 0.3 0.4 8.1 1.4 9.5 2.4 0.1 1.6 7.6 1.0 1.7 0.0 0.3 36.1 0.8 1.2 3.5 0.3 1.1 0.6 0.0 1.2 5.7 1.6 12.3 9.7 11.7 8.5 13.1 1.4 2.0 2.5 6.4 6.1 2.0 6.2 4.4 1.9 1.6 4.9 3.8 2.3 1.7 14.6 4.1 7.2 2.7 3.4 3.5 14.8 4.0 2.8 3.7 4.5 4.5 4.9 4.9 5.2 5.6 6.2 0.0 12.4 40.8 37.0 31.5 3.9 5.2 0.6 39.7 2.2 2.2 15.4 10.0 14.0 3.7 0.0 0.8 39.0 169.6 0.0 4.0 3.5 0.6 4.4 10.9 3.6 3.8 57.5 6.5 26.2 24.3 8.2 1.1 124.5 97.0 12.5 10.3 27.1 63.9 60.0 23.2 6.1 73.6 26.2 2.1 2.5 79.1 140.5 166.8 40.8 34.9 19.6 82.4 75.3 2.0 62.1 7.9 38.4 7.7 109.3 0.4 0.8 3.2 124.9 32.3 37.1 0.2 3.0 3.8 22.6 2.3 78.1 11.8 27.4 13.7 PAIP1 ENSG00000172239 "Poly(A) binding protein interacting protein 1" Q9H074 5 43526267-43557758 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073653, HPA076187" Approved Enhanced "Plasma membrane,Cytosol" No No 60000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "HPA073653: AB_2732234, HPA076187: AB_2686784" "unprognostic (4.70e-2)" "unprognostic (4.30e-2)" "unprognostic (5.37e-2)" "unprognostic (2.65e-2)" "unprognostic (1.62e-2)" "unprognostic (4.74e-2)" "unprognostic (1.13e-3)" "unprognostic (2.98e-1)" "unprognostic (3.17e-2)" "unprognostic (1.62e-2)" "prognostic unfavorable (4.79e-4)" "unprognostic (3.54e-1)" "unprognostic (1.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.20e-1)" "unprognostic (1.52e-1)" "unprognostic (1.30e-1)" 69.5 54.3 47.8 36.6 50.8 56.6 67.4 52.0 64.2 65.1 52.0 57.1 43.3 61.6 57.3 52.0 51.2 53.3 92.5 51.2 52.0 78.0 90.9 50.3 39.4 49.5 49.5 53.7 54.8 74.3 29.3 68.1 50.8 69.1 54.8 95.2 51.3 68.5 155.3 31.1 40.2 65.3 54.3 34.2 46.9 83.6 49.0 47.6 73.6 122.9 45.3 70.1 39.9 56.5 94.5 82.2 158.0 153.7 161.8 127.1 129.1 81.2 180.0 151.5 130.9 77.2 112.8 62.5 136.9 115.5 227.3 60.4 249.3 98.0 153.5 52.2 96.7 49.2 157.1 122.6 142.3 74.2 74.3 135.8 186.1 102.5 191.7 153.1 146.8 45.9 115.9 82.1 153.0 101.7 82.4 101.8 78.5 89.4 104.8 63.8 119.2 88.1 188.8 114.3 89.4 135.3 260.3 99.2 190.0 144.0 141.4 106.3 82.4 136.6 112.5 68.8 103.7 61.7 112.6 94.3 79.7 113.1 120.4 40.4 24.1 46.2 18.9 20.7 25.2 26.4 23.2 26.2 23.7 26.7 28.9 23.2 8.6 24.9 22.5 66.8 23.0 22.1 47.8 50.8 52.0 64.2 51.2 52.0 49.5 49.5 50.8 54.3 49.0 56.5 66.4 32.1 52.2 15.0 39.4 73.3 74.0 78.5 52.3 48.8 78.8 53.1 122.4 78.6 52.7 44.1 20.9 76.3 66.0 33.1 158.5 120.3 182.6 73.8 56.4 71.2 44.9 54.9 30.0 91.6 89.2 64.2 39.3 55.9 24.6 47.4 50.0 49.2 59.4 35.3 25.3 52.1 103.7 40.9 39.7 58.0 76.4 42.0 83.6 20.6 53.8 86.6 24.7 26.7 35.1 116.4 43.8 66.5 43.3 106.4 45.1 148.8 40.9 67.7 26.3 70.2 71.4 171.2 76.6 56.0 66.3 68.1 35.1 49.7 47.7 84.3 PALLD "CGI-151, KIAA0992, SIH002" ENSG00000129116 "Palladin, cytoskeletal associated protein" Q8WX93 4 168497052-168928457 "Disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 527.9;Cardiomyocytes: 591.7;Peritubular cells: 399.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 304.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035905, CAB070159" Enhanced Supported "Plasma membrane,Actin filaments,Mitochondria,Cytosol" No No 27000 "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "Plasma membrane, Mitochondria, Cytosol" "CAB070159: AB_1726016, HPA035905: AB_2674854" "unprognostic (3.59e-2)" "unprognostic (3.99e-1)" "unprognostic (2.55e-2)" "unprognostic (5.03e-3)" "unprognostic (2.51e-1)" "unprognostic (7.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.40e-2)" "unprognostic (3.57e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (3.86e-1)" "unprognostic (8.54e-2)" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.28e-4)" 65.0 35.5 31.7 49.7 27.3 0.9 43.6 11.1 19.9 146.1 0.0 303.3 29.0 301.5 21.9 122.6 118.4 71.0 180.4 27.9 36.2 42.1 12.4 71.7 16.9 29.8 25.9 62.1 13.2 55.6 11.3 62.1 25.1 137.0 74.9 12.8 40.8 205.7 127.7 34.7 64.1 303.1 21.4 60.5 94.8 35.1 24.7 23.3 38.7 47.3 16.6 280.2 85.3 22.7 82.1 39.6 87.9 53.4 77.2 83.9 123.6 53.7 137.6 47.2 66.7 1.1 4.6 36.6 14.4 23.7 29.0 17.0 54.1 138.8 60.5 73.9 16.6 0.8 112.5 10.4 135.5 0.4 1.0 132.8 84.4 85.5 125.4 115.0 20.8 19.7 0.1 0.5 304.5 3.8 23.8 1.4 24.9 20.8 24.1 8.3 81.4 0.8 5.3 16.4 9.0 46.4 102.8 8.1 7.3 151.2 48.6 0.5 64.4 50.3 192.1 20.7 90.1 47.8 0.7 1.7 41.6 1.0 14.2 13.7 3.1 0.0 4.6 1.8 0.2 0.1 0.5 2.4 2.1 0.1 0.6 1.6 0.7 0.6 1.2 0.2 0.8 1.8 31.7 27.3 11.1 19.9 27.9 36.2 29.8 25.9 25.1 21.4 24.7 22.7 22.7 32.1 9.4 167.8 1.5 93.6 527.9 56.8 76.8 6.0 46.0 107.9 591.7 20.0 58.7 44.1 18.8 52.1 8.1 20.9 1.9 27.6 133.1 52.8 181.2 27.7 44.8 0.8 27.8 51.3 115.6 130.5 59.7 51.0 52.6 21.0 47.8 11.2 24.5 26.9 108.4 30.7 18.3 28.9 23.8 146.4 130.1 36.7 23.2 16.9 52.9 55.1 17.5 182.4 6.5 83.0 18.6 399.4 2.6 167.6 9.8 23.4 85.2 4.0 177.5 115.4 227.8 81.0 7.6 34.1 49.3 22.3 9.2 13.4 29.3 113.0 PALM2AKAP2 PALM2-AKAP2 ENSG00000157654 "PALM2 and AKAP2 fusion" "Q8IXS6, Q9Y2D5" 9 109498325-110172512 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.6;naive B-cell: 10.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA058905, HPA074153, HPA076866" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Nuclear bodies" "HPA058905: AB_2683851, HPA074153: AB_2686669, HPA076866: " "unprognostic (7.12e-2)" "unprognostic (1.64e-6)" "unprognostic (7.90e-2)" "unprognostic (3.67e-2)" "unprognostic (2.45e-1)" "unprognostic (3.19e-1)" "unprognostic (9.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.75e-1)" "unprognostic (8.37e-3)" "unprognostic (2.40e-2)" "unprognostic (2.77e-1)" "unprognostic (1.19e-1)" "unprognostic (2.05e-3)" "unprognostic (7.77e-2)" "unprognostic (1.98e-4)" "unprognostic (3.36e-5)" 97.0 13.5 21.8 37.3 21.1 9.9 17.5 6.9 22.7 28.5 0.0 17.4 14.8 28.8 8.5 26.5 14.7 37.4 93.8 15.7 18.5 30.8 38.2 69.1 32.2 18.1 26.6 9.3 13.1 14.0 0.1 97.9 20.3 14.9 18.1 3.3 38.0 25.1 17.0 10.1 13.3 48.5 10.5 38.4 18.5 4.6 38.8 45.4 25.6 24.3 31.7 43.0 0.4 26.3 20.6 7.7 112.5 0.1 110.8 93.0 33.4 116.0 141.3 101.6 93.4 134.6 17.9 92.1 30.6 129.6 146.2 28.9 9.5 98.8 185.4 68.9 12.5 9.2 30.4 11.0 75.9 12.4 256.2 109.8 24.7 183.3 280.4 62.5 150.9 14.5 0.3 76.2 204.7 1.2 61.9 31.1 47.2 9.1 62.6 5.5 98.2 25.3 72.4 2.8 25.2 1.5 10.3 9.5 26.4 87.8 4.1 22.2 240.0 94.0 77.9 137.5 108.8 52.5 89.1 52.5 81.4 51.3 73.9 2.9 0.1 1.3 1.0 0.2 0.2 10.6 1.2 1.4 1.2 10.3 0.7 0.8 0.5 2.2 0.0 2.4 3.9 1.4 21.8 21.1 6.9 22.7 15.7 18.5 18.1 26.6 20.3 10.5 38.8 26.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PAM "PAL, PHM" ENSG00000145730 "Peptidylglycine alpha-amidating monooxygenase" P19021 5 102753981-103031105 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1560.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1406.5;Enteroendocrine cells: 321.4;Inhibitory neurons: 487.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 529.9;fHDF/TERT166: 714.5;hTERT-RPE1: 562.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026119, HPA042260" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA 98000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus, Cytosol" "CAB026119: , HPA042260: AB_2677919" "unprognostic (4.30e-3)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.63e-4)" "unprognostic (4.23e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (7.58e-2)" "unprognostic (6.62e-2)" "unprognostic (2.71e-1)" "unprognostic (9.91e-2)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.08e-1)" "unprognostic (9.79e-2)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" 119.3 202.5 71.6 34.6 81.4 10.1 99.0 50.7 82.5 595.0 96.2 125.1 52.6 140.9 678.2 69.4 87.6 97.3 1560.4 75.2 179.9 116.0 20.1 88.3 27.7 86.5 99.8 136.4 104.4 257.8 137.0 60.0 170.9 91.6 80.4 37.6 205.4 236.5 155.3 66.9 52.1 157.9 55.7 52.5 131.6 22.4 106.0 17.9 95.1 159.4 30.5 103.3 116.1 50.0 111.3 16.3 195.9 87.2 529.9 314.8 78.0 307.6 457.0 89.1 268.9 53.5 143.2 0.1 65.0 714.5 125.7 36.8 11.0 135.3 244.0 13.5 44.7 22.9 60.0 17.7 80.3 7.4 23.9 173.4 57.3 65.6 49.2 562.6 186.8 8.9 0.9 15.0 255.6 22.9 0.1 3.2 35.3 19.7 59.3 8.5 108.9 62.4 346.1 13.0 92.3 63.9 131.2 8.3 83.3 114.0 34.0 7.3 144.9 280.8 72.4 133.3 93.4 33.1 8.6 0.4 322.3 30.8 247.6 4.2 8.0 0.2 20.7 1.5 14.9 0.8 12.3 15.6 3.1 0.4 4.1 6.8 16.6 26.3 3.4 1.6 19.9 10.8 71.6 81.4 50.7 82.5 75.2 179.9 86.5 99.8 170.9 55.7 106.0 50.0 45.7 54.5 39.3 47.0 3.9 28.2 12.0 26.1 12.0 19.1 27.5 12.1 1406.5 0.0 30.4 60.7 2.1 1.6 12.6 13.7 7.9 12.6 8.8 47.6 48.6 63.5 321.4 3.4 229.2 21.5 40.6 220.4 26.0 83.0 9.5 68.3 74.6 3.5 5.9 8.4 487.7 13.8 18.3 10.3 48.3 8.1 60.3 9.3 37.4 192.0 9.5 11.6 22.6 154.8 9.3 30.6 6.3 58.6 12.1 26.4 4.8 43.8 19.2 3.8 19.7 36.4 44.9 2.6 5.6 8.0 23.7 6.7 16.6 19.3 6.3 18.2 PAMR1 "DKFZP586H2123, RAMP" ENSG00000149090 "Peptidase domain containing associated with muscle regeneration 1" Q6UXH9 11 35431823-35530300 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Astrocytes: 380.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 86.9;ASC TERT1: 354.7;BJ hTERT+: 357.7;fHDF/TERT166: 86.7;HSkMC: 123.1;U-87 MG: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA 5600000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (3.38e-1)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.07e-2)" "unprognostic (6.92e-2)" "unprognostic (3.32e-2)" "unprognostic (4.07e-2)" "unprognostic (1.91e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.08e-5)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.08e-1)" "unprognostic (9.98e-2)" "unprognostic (8.25e-2)" 32.8 14.9 25.1 0.6 27.4 0.0 15.4 22.0 23.2 59.9 13.9 14.9 4.5 58.2 18.3 10.0 22.6 20.3 23.2 22.5 26.2 7.1 12.6 5.9 1.3 37.9 35.9 3.4 5.3 1.7 6.4 55.9 32.4 21.2 6.6 0.9 5.7 17.9 2.7 19.8 9.9 14.9 46.1 5.7 5.4 0.2 34.1 2.8 7.0 9.0 1.7 28.0 41.3 38.8 0.0 0.0 0.1 0.0 86.9 354.7 0.1 42.8 357.7 4.9 8.3 32.7 0.0 0.0 0.0 86.7 0.1 0.1 0.0 0.0 3.3 0.0 0.8 0.0 0.0 0.0 50.1 0.0 0.0 123.1 1.8 9.7 1.3 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.7 0.0 0.2 0.0 0.2 0.2 0.0 8.4 0.1 0.0 0.0 0.0 0.0 14.3 2.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 82.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 27.4 22.0 23.2 22.5 26.2 37.9 35.9 32.4 46.1 34.1 38.8 2.5 0.0 0.0 380.3 0.0 19.1 1.4 14.8 1.2 0.1 0.7 19.7 1.3 0.0 2.4 1.8 0.0 2.2 0.0 0.0 0.0 1.4 0.1 4.5 26.2 1.1 0.0 0.0 13.1 0.0 1.4 50.2 1.1 0.8 0.0 0.6 0.0 0.0 2.0 0.0 8.2 0.2 0.0 0.0 5.5 0.1 0.3 0.5 1.8 28.1 0.6 0.0 0.0 9.5 1.4 0.1 0.0 0.0 0.0 0.4 0.2 0.0 1.8 0.2 0.0 1.6 5.8 0.0 0.2 0.1 9.2 3.4 0.6 0.2 0.0 0.2 PAN3 ENSG00000152520 "Poly(A) specific ribonuclease subunit PAN3" Q58A45 13 28138506-28295335 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 154.6;Microglial cells: 209.9;Oligodendrocyte precursor cells: 171.4;Oligodendrocytes: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028817 Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" "HPA028817: AB_10602016" "unprognostic (3.25e-2)" "unprognostic (2.10e-1)" "unprognostic (3.55e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (7.39e-2)" "unprognostic (8.17e-2)" "unprognostic (1.52e-1)" "unprognostic (4.26e-3)" "unprognostic (5.78e-2)" "unprognostic (6.56e-2)" "unprognostic (2.29e-2)" "unprognostic (4.22e-2)" "unprognostic (2.76e-2)" "unprognostic (1.21e-1)" "unprognostic (8.54e-2)" "unprognostic (2.42e-2)" 17.1 9.8 7.8 14.2 8.9 31.3 18.1 16.4 10.8 16.1 12.2 13.9 9.6 15.3 20.6 12.5 16.1 11.0 8.5 7.9 8.1 13.4 11.0 14.6 21.5 8.5 8.4 16.3 17.0 10.1 12.5 11.8 8.9 14.1 12.6 15.8 14.8 12.1 6.8 20.1 18.7 10.8 8.6 25.8 13.0 14.2 7.9 21.5 17.4 5.7 19.4 13.1 15.3 11.8 9.9 6.2 16.8 17.9 8.2 11.6 13.9 10.1 16.1 10.5 10.0 10.3 21.2 34.9 7.1 14.9 11.8 14.4 15.1 11.9 17.8 19.8 7.9 28.3 8.7 8.9 10.9 21.6 17.0 11.5 11.9 8.9 18.1 13.5 14.2 16.2 14.1 10.4 11.6 13.6 23.6 52.2 18.0 13.6 5.9 54.5 17.9 12.8 16.7 13.2 15.8 12.5 11.9 17.3 13.9 10.3 9.2 40.6 13.8 10.5 8.9 10.3 9.8 7.9 6.1 35.6 6.2 16.2 13.1 22.8 10.1 13.4 9.0 9.6 9.6 12.3 10.2 9.2 9.8 11.4 11.5 11.1 22.5 11.9 14.4 15.6 8.7 11.2 7.8 8.9 16.4 10.8 7.9 8.1 8.5 8.4 8.9 8.6 7.9 11.8 32.3 16.0 19.5 97.9 42.9 66.3 16.2 10.2 18.8 27.3 36.1 16.9 7.8 17.2 14.8 16.5 29.2 18.1 51.1 13.6 1.9 13.6 21.3 33.2 25.7 26.8 27.1 61.0 131.4 12.5 15.9 23.7 19.4 38.5 16.5 26.3 28.9 10.7 13.7 26.9 154.6 18.0 16.2 41.4 88.0 12.4 26.4 34.7 56.9 209.9 35.4 13.7 35.0 171.4 222.3 13.6 21.5 21.8 28.9 35.0 13.2 14.3 16.6 37.8 13.1 31.6 26.2 26.5 23.0 22.5 80.7 24.1 36.1 17.1 17.0 31.2 PANK2 "C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN" ENSG00000125779 "Pantothenate kinase 2" Q9BZ23 20 3888839-3929887 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Coenzyme A biosynthesis" "Kinase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008440 Approved Supported Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA008440: AB_1079559" "unprognostic (4.50e-2)" "unprognostic (7.96e-3)" "unprognostic (2.26e-1)" "unprognostic (1.39e-2)" "unprognostic (1.68e-1)" "unprognostic (6.00e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (2.75e-1)" "unprognostic (3.39e-1)" "unprognostic (2.52e-1)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" "unprognostic (6.01e-3)" "unprognostic (1.73e-2)" "unprognostic (2.18e-3)" "unprognostic (2.63e-1)" "unprognostic (1.81e-1)" 13.0 12.3 14.5 16.8 13.7 20.9 12.2 15.3 15.9 11.9 14.1 11.4 8.4 11.0 11.3 20.0 16.3 12.1 8.7 15.5 13.5 15.7 18.3 14.1 18.5 12.7 14.1 12.9 10.3 10.9 8.9 15.3 13.3 12.0 14.2 10.3 11.9 10.7 9.6 11.7 11.6 13.7 12.7 14.9 9.1 25.9 13.9 16.8 15.4 11.2 22.0 15.6 9.9 12.4 39.3 29.4 33.7 18.6 39.3 32.6 15.0 25.6 34.2 38.3 48.3 40.8 25.4 34.6 10.6 34.9 70.2 34.9 34.7 57.3 49.3 8.8 9.8 47.4 22.7 80.2 33.3 33.6 15.9 28.7 26.4 39.7 28.7 17.0 36.0 23.3 34.7 30.5 42.5 11.7 30.0 30.3 28.8 22.9 19.5 20.3 46.0 22.4 26.2 45.7 36.2 16.7 30.0 44.3 78.1 32.6 23.6 28.1 24.6 47.7 17.8 60.7 43.3 14.0 50.8 23.3 15.0 30.7 34.2 3.0 10.5 3.4 3.6 11.1 3.5 3.8 3.7 3.4 8.5 4.5 4.1 3.4 5.9 6.8 9.4 3.0 5.9 4.0 14.5 13.7 15.3 15.9 15.5 13.5 12.7 14.1 13.3 12.7 13.9 12.4 23.8 19.2 11.7 23.8 29.2 25.5 17.5 12.0 41.5 22.0 15.8 17.3 9.8 7.2 13.4 14.7 25.0 29.4 38.6 14.4 23.5 19.4 83.1 24.1 20.6 26.7 20.3 42.7 28.6 17.8 36.0 21.1 24.5 24.1 7.6 20.1 26.0 14.0 33.8 35.3 25.3 12.7 10.2 52.8 37.9 17.3 21.1 34.3 19.6 29.0 55.0 14.1 35.0 23.1 17.7 15.9 12.8 22.6 33.2 20.9 15.1 20.6 20.2 21.1 6.6 14.1 23.1 54.6 25.9 37.7 24.3 18.6 31.6 21.2 15.0 20.0 PAPLN MGC50452 ENSG00000100767 "Papilin, proteoglycan like sulfated glycoprotein" O95428 14 73237497-73274640 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 119.8;Endometrial stromal cells: 37.9;Leydig cells: 34.5;Peritubular cells: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "neutrophil: 2.5;plasmacytoid DC: 5.4" "Group enriched" "Detected in many" 7 "dendritic cells: 5.4;granulocytes: 2.5" "Cell line enhanced" "Detected in many" "HHSteC: 16.1;HSkMC: 30.6;hTCEpi: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA048682, HPA053453" Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 76000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA048682: AB_2680492, HPA053453: AB_2682155" "unprognostic (1.97e-3)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (3.56e-3)" "unprognostic (7.42e-2)" "unprognostic (7.91e-3)" "unprognostic (2.01e-2)" "unprognostic (2.46e-3)" "unprognostic (9.13e-3)" "unprognostic (3.69e-2)" "unprognostic (1.41e-1)" "unprognostic (4.87e-2)" "unprognostic (1.89e-2)" "unprognostic (2.14e-2)" "unprognostic (3.05e-3)" "unprognostic (2.69e-2)" "unprognostic (5.58e-2)" 16.1 6.6 15.7 8.4 17.0 2.3 10.7 12.1 23.5 30.3 15.7 13.4 3.0 20.4 14.9 7.1 23.0 5.6 8.0 14.4 13.3 42.6 3.2 13.4 15.2 14.1 14.6 16.8 4.0 0.4 16.4 4.0 13.1 13.6 4.5 9.5 7.5 7.5 2.1 15.7 17.8 6.3 12.3 29.1 11.3 6.4 14.4 5.1 24.8 1.8 13.6 5.1 9.1 12.3 2.7 2.6 1.0 0.4 1.9 2.3 5.8 0.5 0.0 0.1 0.2 3.4 0.8 0.5 2.7 0.0 0.1 4.3 2.7 2.0 0.3 3.0 3.9 1.2 4.7 0.3 16.1 0.4 2.1 30.6 11.4 0.5 1.7 0.2 0.6 2.5 0.8 0.3 0.0 1.4 0.3 3.0 0.6 0.3 0.8 0.4 0.3 2.8 2.3 0.6 0.3 0.5 6.2 7.0 1.3 7.9 0.2 4.8 0.5 0.7 2.3 0.2 0.3 1.3 0.1 0.3 1.4 1.4 0.6 0.8 0.5 0.3 0.2 0.3 0.1 0.4 0.1 0.2 0.1 0.5 0.2 0.2 2.5 0.3 0.2 5.4 0.3 0.1 15.7 17.0 12.1 23.5 14.4 13.3 14.1 14.6 13.1 12.3 14.4 12.3 0.4 0.0 2.6 119.8 0.3 2.0 0.7 5.1 0.6 1.2 1.8 1.4 1.9 7.2 4.8 5.5 8.4 0.5 5.7 0.4 0.0 4.0 0.3 11.8 37.9 3.4 0.0 0.0 0.3 0.0 1.1 8.3 0.5 16.1 0.0 0.2 3.3 0.1 1.2 0.0 0.9 0.4 2.0 0.3 1.6 1.7 34.5 1.8 1.8 10.3 1.6 15.7 0.0 3.0 0.3 0.4 0.0 44.0 0.2 1.4 0.2 10.2 3.7 3.0 6.6 1.4 1.8 0.6 0.1 0.8 3.0 0.4 0.7 0.1 1.0 0.4 PAPPA "ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1" ENSG00000182752 "Pappalysin 1" Q13219 9 116153791-116402321 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "placenta: 72.3" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 92.2;Collecting duct cells: 165.5;Endometrial stromal cells: 101.3;Proximal tubular cells: 51.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 50.0;ASC TERT1: 37.8;HSkMC: 137.4;U-138 MG: 36.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA001667, CAB016724" Enhanced "Secreted in female reproductive system" NA NA 78000000 "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "CAB016724: , HPA001667: AB_1854960" "unprognostic (3.25e-1)" "unprognostic (6.18e-6)" "unprognostic (2.47e-1)" "unprognostic (6.49e-2)" "unprognostic (2.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (5.42e-3)" "unprognostic (5.44e-2)" "unprognostic (3.87e-2)" "unprognostic (6.87e-3)" "unprognostic (8.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.37e-3)" "unprognostic (2.48e-1)" "unprognostic (4.01e-1)" "unprognostic (1.02e-3)" 4.1 1.5 0.7 1.8 0.2 0.0 0.8 0.5 0.9 4.2 2.2 2.0 0.3 3.9 0.6 2.5 3.1 2.0 2.6 0.3 1.6 3.8 0.3 1.9 1.2 2.5 2.5 2.5 0.8 9.1 0.4 72.3 2.0 1.1 1.5 1.0 0.4 2.1 0.3 0.9 0.9 4.2 0.4 0.3 1.1 0.8 1.6 0.8 1.0 1.4 1.0 4.5 2.4 1.3 0.0 14.9 22.3 0.0 50.0 37.8 0.0 12.2 21.4 3.3 5.6 0.0 0.0 0.0 0.0 8.6 1.1 1.7 0.0 0.0 15.6 0.0 0.0 2.6 12.8 0.1 24.3 0.0 0.0 137.4 0.0 16.4 1.9 26.9 0.1 0.0 0.5 0.0 3.8 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.6 0.0 0.6 0.1 0.1 1.2 1.8 0.0 0.0 6.8 0.0 0.0 28.9 36.3 1.8 1.0 1.4 0.0 0.0 0.0 25.8 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.5 0.9 0.3 1.6 2.5 2.5 2.0 0.4 1.6 1.3 0.2 0.0 1.5 3.9 1.0 2.9 0.2 4.0 92.2 17.6 0.8 0.4 3.4 0.0 1.6 165.5 12.5 0.5 0.1 0.1 9.8 5.9 20.1 4.7 101.3 1.4 0.0 0.0 10.0 0.9 19.5 31.8 0.5 2.6 1.3 10.4 4.6 0.1 0.4 0.0 19.6 0.0 0.0 0.0 5.8 17.9 14.3 1.0 1.8 7.5 0.0 2.5 1.0 15.1 2.9 0.3 0.0 8.6 1.2 1.2 0.2 51.5 1.6 2.9 0.0 3.3 10.9 2.2 0.6 19.7 1.1 14.0 1.3 0.2 0.1 0.3 PAPPA2 "PAPP-A2, PAPPE, PLAC3" ENSG00000116183 "Pappalysin 2" Q9BXP8 1 176463171-176845601 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 56.8" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 140.7;Extravillous trophoblasts: 71.9;Muller glia cells: 41.4;Oligodendrocytes: 37.6;Syncytiotrophoblasts: 74.0" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-87 MG: 19.8" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 5.6" "HPA018412, HPA018430" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted in female reproductive system" NA NA 2000000 "Cluster 28: Placenta - Pregnancy" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Endoplasmic reticulum, Vesicles" "HPA018412: AB_1854962, HPA018430: AB_1854961" "unprognostic (2.90e-1)" "unprognostic (1.58e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-2)" "unprognostic (9.04e-2)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (3.54e-2)" "unprognostic (1.29e-2)" "unprognostic (4.39e-2)" "unprognostic (2.85e-2)" "unprognostic (1.52e-4)" "unprognostic (1.85e-1)" "unprognostic (8.18e-4)" "unprognostic (4.35e-2)" 0.6 0.0 0.5 0.3 0.3 0.0 2.5 0.3 0.4 6.6 0.0 0.6 0.0 0.6 0.3 0.0 0.2 1.8 0.3 0.5 0.2 6.3 0.6 0.1 0.0 0.5 0.5 0.0 2.5 0.0 1.1 56.8 0.6 0.2 0.5 3.7 0.1 0.6 0.0 0.1 0.2 0.5 0.4 0.0 1.6 0.4 0.3 0.0 0.5 0.0 0.0 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.2 4.3 2.1 3.5 0.9 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.7 0.5 0.5 0.2 0.0 0.0 0.1 0.7 0.0 0.0 0.3 1.6 1.3 0.1 0.6 0.3 0.4 0.0 19.8 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.4 0.5 0.2 0.5 0.5 0.6 0.4 0.3 0.4 0.0 0.0 0.0 26.1 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.1 0.8 0.0 0.0 5.5 0.0 1.5 0.0 0.1 11.7 0.0 2.6 0.2 0.1 0.3 140.7 0.0 16.3 0.2 71.9 0.8 0.0 0.0 0.0 0.0 0.0 0.6 1.3 0.0 10.8 0.2 0.0 0.0 0.0 1.9 11.5 0.0 0.0 2.8 0.0 41.4 0.0 5.0 37.6 0.8 0.0 10.9 0.0 0.0 0.0 0.5 0.0 2.4 6.6 0.0 1.2 1.3 2.2 0.0 0.0 74.0 0.0 0.0 0.2 0.1 PAQR6 "FLJ22672, PRdelta" ENSG00000160781 "Progestin and adipoQ receptor family member 6" Q6TCH4 1 156243320-156248117 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 37 "brain: 674.6;choroid plexus: 196.2" "Group enriched" "Detected in many" 5 "Astrocytes: 44.1;Muller glia cells: 70.9;Oligodendrocytes: 65.1" "Cancer enriched" "Detected in all" 6 "glioma: 34.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 5.7" "Lineage enriched" "Detected in single" 7 "NK-cells: 5.7" "Cell line enhanced" "Detected in many" "RT4: 14.8;T-47d: 17.8;U-266/70: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA No "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (1.64e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (7.42e-2)" "unprognostic (5.52e-2)" "unprognostic (4.50e-3)" "unprognostic (4.75e-1)" "unprognostic (2.25e-1)" "unprognostic (2.57e-1)" "unprognostic (3.13e-1)" "unprognostic (4.25e-3)" "prognostic unfavorable (1.99e-4)" "prognostic unfavorable (1.58e-8)" "unprognostic (1.26e-2)" "unprognostic (1.34e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.86e-4)" 1.9 1.8 275.4 0.8 321.1 6.1 2.7 319.1 674.6 3.2 196.2 7.9 1.3 0.9 0.4 4.8 3.4 1.3 2.3 240.1 271.1 6.3 7.2 2.6 0.4 413.7 327.9 1.8 1.9 0.4 11.8 0.7 397.2 7.0 0.8 6.7 3.1 1.0 1.5 11.2 3.7 0.5 369.6 4.7 3.3 4.2 320.9 0.6 3.7 0.3 0.7 1.9 4.2 380.4 1.7 1.5 3.8 3.1 0.8 0.5 9.9 0.3 0.6 0.2 0.2 1.3 6.7 3.7 2.0 0.7 0.4 7.5 0.0 1.6 0.5 2.2 2.6 2.4 2.6 1.5 0.5 1.2 7.5 1.6 4.3 2.8 3.0 3.7 0.2 8.6 2.4 9.4 0.5 7.4 0.5 1.1 5.3 1.1 1.3 1.8 0.9 2.4 3.0 14.8 3.3 6.8 0.5 1.3 5.0 6.9 17.8 1.7 0.6 1.2 6.2 2.0 0.8 27.4 7.7 2.4 0.5 10.5 1.2 0.0 0.0 0.0 0.2 0.0 0.8 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.6 0.0 0.1 275.4 321.1 319.1 674.6 240.1 271.1 413.7 327.9 397.2 369.6 320.9 380.4 0.6 0.0 0.5 44.1 1.7 1.3 0.5 1.8 0.0 3.9 1.8 2.0 3.5 1.5 1.3 0.0 0.0 0.1 1.0 0.9 0.0 0.7 0.4 1.3 0.6 0.7 4.2 3.2 1.5 3.4 0.2 1.3 4.6 1.7 1.3 1.1 0.7 0.9 0.6 6.7 1.4 0.5 2.0 1.3 0.4 0.8 0.3 0.9 0.0 3.7 0.6 70.9 0.0 6.0 65.1 1.8 0.0 2.2 3.5 0.7 0.8 0.4 2.3 11.2 0.0 0.6 0.5 1.3 0.5 0.6 1.4 0.3 2.3 0.5 1.1 0.5 PARL "PRO2207, PSARL, PSARL1, RHBDS1" ENSG00000175193 "Presenilin associated rhomboid like" Q9H300 3 183829271-183884933 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA019545 Approved Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA019545: AB_1855796" "unprognostic (2.10e-1)" "unprognostic (1.53e-3)" "unprognostic (5.88e-2)" "unprognostic (1.17e-2)" "unprognostic (5.76e-2)" "unprognostic (9.55e-2)" "unprognostic (3.17e-3)" "unprognostic (8.97e-2)" "unprognostic (1.81e-1)" "unprognostic (3.62e-3)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (4.28e-2)" "unprognostic (5.49e-2)" "unprognostic (2.58e-1)" "unprognostic (1.73e-1)" "prognostic favorable (9.11e-5)" 38.4 35.8 46.5 26.6 48.2 33.8 40.3 47.4 66.2 33.8 50.7 47.7 29.2 31.9 57.7 36.7 30.2 19.7 54.1 46.6 48.2 39.6 45.0 28.4 32.0 47.7 48.7 31.7 49.9 39.7 32.0 25.5 47.4 37.1 41.9 32.7 40.5 30.3 54.9 37.1 34.7 29.7 47.2 36.2 42.6 26.7 47.6 34.5 31.4 51.6 33.8 38.9 31.5 48.4 115.1 55.6 39.7 33.0 38.8 42.1 80.2 39.2 59.4 80.5 65.0 172.0 59.0 47.8 90.0 56.7 73.5 49.2 64.1 68.0 90.0 71.6 76.1 73.9 35.5 96.9 57.3 73.9 61.6 60.0 85.4 58.0 70.7 38.5 59.0 82.4 42.6 45.0 69.2 131.0 148.3 194.3 105.5 100.6 53.3 64.7 72.8 92.0 79.0 97.6 37.9 52.0 47.6 162.9 107.8 48.1 159.2 143.5 31.8 29.3 63.0 60.9 108.2 89.2 65.7 116.0 56.6 75.1 35.5 97.5 143.1 133.4 51.3 107.8 60.9 62.4 57.3 59.9 132.4 59.1 68.7 54.2 41.3 67.1 83.3 79.7 73.7 116.1 46.5 48.2 47.4 66.2 46.6 48.2 47.7 48.7 47.4 47.2 47.6 48.4 30.3 22.4 19.7 17.9 37.6 30.3 54.9 93.5 26.7 35.9 31.8 31.5 41.2 35.8 44.5 31.3 31.3 58.9 38.4 24.4 117.4 63.9 24.0 15.2 18.3 30.2 33.7 23.3 23.4 84.7 49.0 35.1 28.1 13.7 69.8 33.1 33.2 30.4 77.7 33.7 24.1 42.0 77.3 56.2 55.7 9.7 28.9 57.5 42.7 33.7 79.3 55.9 50.4 17.1 28.0 60.3 35.1 27.1 42.3 55.4 47.3 86.0 30.5 51.1 6.6 44.8 96.6 47.8 47.4 40.2 30.0 42.1 40.9 49.0 49.2 58.8 PARP15 "ARTD7, FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577628-122639047 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 23.1;intestine: 42.1;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 19.2;B-cells: 88.4;dendritic cells: 38.6;granulocytes: 19.6;NK-cells: 21.6;Plasma cells: 18.6;T-cells: 31.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 7.6;JURKAT: 5.1;REH: 3.5;THP-1: 3.7;TIME: 8.9" "Low region specificity" "Detected in single" HPA035757 Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" Mitochondria "HPA035757: AB_10669656" "unprognostic (8.19e-3)" "unprognostic (2.88e-3)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (9.01e-5)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (3.91e-2)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (9.24e-7)" "unprognostic (9.03e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (1.22e-2)" 3.7 1.2 3.1 25.7 2.7 23.1 1.8 4.2 3.8 1.7 1.2 3.8 2.6 1.9 1.3 2.0 2.0 4.4 1.7 2.1 1.2 1.7 3.2 9.0 44.4 1.8 2.3 0.7 0.8 0.2 0.7 2.5 1.7 1.8 4.8 2.2 2.2 1.1 6.0 1.2 42.1 1.9 0.7 67.2 4.1 2.5 2.0 8.3 3.0 1.9 50.3 4.5 1.6 3.6 0.3 0.2 0.3 0.3 0.1 0.2 0.3 0.2 0.1 0.0 0.0 0.2 0.7 0.3 0.4 0.1 0.2 0.3 0.0 0.0 0.0 0.7 0.1 7.6 0.5 0.3 0.1 0.5 0.3 1.5 0.1 0.3 0.1 0.2 1.7 5.1 0.2 1.3 0.0 0.3 2.3 0.4 0.4 0.1 0.1 3.5 0.2 0.3 0.0 0.6 0.5 0.3 0.1 0.1 0.1 0.3 0.5 3.7 8.9 0.2 0.6 0.3 0.2 0.6 0.4 1.6 0.4 0.2 0.1 1.8 0.2 0.1 7.2 0.3 5.8 9.4 4.4 5.4 0.8 9.3 3.8 4.8 0.5 3.9 0.7 1.0 4.2 2.2 3.1 2.7 4.2 3.8 2.1 1.2 1.8 2.3 1.7 0.7 2.0 3.6 0.8 19.2 15.9 0.0 88.4 0.5 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 2.1 0.0 0.0 0.1 38.6 0.1 0.0 0.0 0.2 0.3 0.1 1.2 0.0 7.4 0.1 0.0 0.1 2.7 2.6 0.3 19.6 0.0 2.2 0.6 8.3 0.0 0.2 0.0 0.0 5.1 1.4 0.2 0.0 6.4 1.8 6.5 4.7 0.0 21.6 0.0 0.1 0.1 0.0 0.0 18.6 0.0 0.0 0.1 10.5 0.0 0.0 0.7 0.4 0.1 1.6 0.4 0.0 0.3 31.1 0.0 0.0 0.0 PARVB CGI-56 ENSG00000188677 "Parvin beta" Q9HBI1 22 43999211-44172939 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.9;tongue: 170.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 113.2;Hofbauer cells: 90.6;Macrophages: 78.7" "Cancer enhanced" "Detected in all" "melanoma: 20.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 158.0;RPMI-8226: 159.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062601, HPA072217" Enhanced Approved Cytosol NA NA 24000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA062601: AB_2684803, HPA072217: " "unprognostic (2.41e-1)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.83e-2)" "unprognostic (2.10e-3)" "unprognostic (7.65e-3)" "unprognostic (1.28e-1)" "unprognostic (1.73e-2)" "unprognostic (2.28e-1)" "unprognostic (6.46e-2)" "unprognostic (1.03e-2)" "unprognostic (6.45e-2)" "unprognostic (1.28e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-2)" "unprognostic (4.19e-2)" "unprognostic (7.05e-3)" 42.6 30.7 26.7 21.3 19.4 43.4 33.0 18.7 24.3 21.8 22.6 21.8 7.4 22.2 13.5 11.9 19.2 10.7 86.9 34.1 24.7 23.0 14.4 29.7 19.2 23.3 25.7 27.1 11.9 18.5 24.3 21.4 26.9 17.0 8.6 10.5 11.4 13.7 195.9 14.2 18.6 22.9 20.8 35.3 15.0 6.6 28.3 9.4 12.8 170.6 16.1 23.9 16.7 19.7 23.5 27.7 0.4 19.1 28.1 35.5 0.1 32.4 20.1 20.9 15.6 28.9 13.8 0.2 17.5 87.2 16.4 0.9 45.9 2.1 11.5 33.1 28.5 100.4 45.8 0.2 46.5 76.5 86.7 55.4 24.0 15.2 0.2 15.0 158.0 0.4 36.6 67.0 22.9 15.9 0.4 50.4 9.8 20.4 18.7 0.2 0.8 159.5 0.5 0.6 24.6 17.1 8.6 1.6 84.9 3.3 15.9 30.7 99.2 19.0 20.0 29.4 3.4 16.2 15.3 0.7 82.8 22.1 106.0 6.9 6.8 1.6 1.0 7.1 1.6 6.2 1.7 1.5 7.2 6.4 0.4 0.9 4.7 0.8 2.9 14.9 2.4 9.5 26.7 19.4 18.7 24.3 34.1 24.7 23.3 25.7 26.9 20.8 28.3 19.7 70.3 0.0 10.6 5.2 48.2 5.2 3.4 1.3 4.0 11.2 8.3 9.4 55.0 4.3 0.9 1.8 16.7 1.0 29.0 0.3 27.4 1.5 6.6 8.0 12.6 63.7 1.2 113.2 15.1 3.1 10.8 18.4 4.1 11.7 64.7 20.2 53.2 12.5 90.6 6.7 12.5 0.7 6.1 49.7 39.5 21.6 19.9 78.7 19.6 28.1 44.7 8.9 9.2 2.5 5.9 4.7 0.0 10.9 58.1 5.1 0.0 30.0 3.8 15.2 6.6 18.2 14.2 1.9 5.8 0.7 4.4 1.8 16.7 2.3 0.6 1.5 PATE1 PATE ENSG00000171053 "Prostate and testis expressed 1" Q8WXA2 11 125746279-125749867 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "epididymis: 1868.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.3;NB-4: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA076587 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "HPA076587: AB_2732316" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1868.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 209.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PATE2 "C11orf38, LVLF3112, PATE-M, UNQ3112" ENSG00000196844 "Prostate and testis expressed 2" Q6UY27 11 125776113-125778828 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "epididymis: 450.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 8.4;Early spermatids: 4.4;Excitatory neurons: 2.7;Inhibitory neurons: 3.1;Late spermatids: 13.7;Oligodendrocyte precursor cells: 3.0;Spermatocytes: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.28e-1)" "unprognostic (7.26e-2)" "unprognostic (2.95e-1)" "unprognostic (1.18e-2)" "unprognostic (2.63e-1)" "unprognostic (6.84e-3)" "unprognostic (1.55e-2)" "unprognostic (5.08e-1)" "unprognostic (2.55e-1)" 0.0 0.1 0.5 0.0 0.6 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 450.6 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.4 0.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.0 0.7 0.4 0.0 0.4 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.2 0.9 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.8 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PATE3 "HEL-127, PATE-DJ" ENSG00000236027 "Prostate and testis expressed 3" B3GLJ2 11 125788127-125791600 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "epididymis: 158.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 25: Spermatids - Spermatogenesis" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 158.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PATE4 "FLJ41047, PATE-B" ENSG00000237353 "Prostate and testis expressed 4" P0C8F1 11 125833316-125840072 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "seminal vesicle: 106.8" "Group enriched" "Detected in some" 70 "Early spermatids: 22.9;Late spermatids: 19.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045632 Approved "Secreted in male reproductive system" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Spermatids - Unknown function" "HPA045632: AB_10960489" "unprognostic (4.90e-1)" "unprognostic (2.93e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" 0.1 0.2 0.7 0.1 0.6 0.4 0.1 1.8 1.3 0.1 0.0 0.0 0.1 0.1 14.9 0.1 0.1 0.1 0.1 0.5 0.2 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 2.9 0.1 0.7 0.1 106.8 0.2 0.4 0.1 0.0 0.0 0.1 0.1 0.4 0.4 0.0 0.4 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.4 0.2 0.3 0.5 0.2 0.3 0.1 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.6 1.8 1.3 0.5 0.2 0.0 0.0 0.1 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PATL2 Pat1a ENSG00000229474 "PAT1 homolog 2" C9JE40 15 44665732-44711316 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.7;lymphoid tissue: 17.2" "Cell type enhanced" "Detected in many" "B-cells: 29.2;dendritic cells: 19.1;NK-cells: 51.5;Plasma cells: 15.7;T-cells: 29.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 21.6;memory CD4 T-cell: 6.0;memory CD8 T-cell: 17.7;naive CD8 T-cell: 12.8" "Lineage enriched" "Detected in many" 6 "T-cells: 21.6" "Cell line enriched" "Detected in some" 28 "U-266/70: 124.9" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.28e-2)" "unprognostic (8.59e-3)" "unprognostic (3.30e-3)" "unprognostic (5.55e-2)" "unprognostic (7.28e-2)" "unprognostic (1.11e-2)" "unprognostic (3.00e-3)" "unprognostic (7.82e-2)" "unprognostic (3.69e-1)" "unprognostic (1.75e-2)" "unprognostic (1.44e-2)" "unprognostic (9.48e-2)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (9.69e-4)" 0.9 1.1 0.8 7.7 1.1 7.7 1.3 0.6 0.8 0.3 1.5 2.1 2.4 1.1 1.7 0.6 1.4 2.3 0.7 0.7 0.8 0.5 1.7 3.9 17.2 1.8 1.1 0.9 0.6 0.4 0.2 1.0 1.1 0.8 2.5 0.1 2.5 0.6 0.3 2.7 3.2 0.8 0.9 13.9 3.2 0.5 1.2 3.6 0.7 0.0 10.8 2.1 0.2 1.4 0.2 0.0 0.0 0.1 0.0 1.1 2.8 0.1 0.4 0.9 0.9 0.6 1.2 0.9 0.1 0.3 1.8 1.3 0.1 0.2 0.5 2.1 0.0 1.2 0.0 0.1 0.5 0.5 0.7 1.2 0.1 0.5 0.3 0.2 0.0 1.4 0.2 4.5 0.3 0.3 0.1 1.4 0.4 0.1 0.1 1.8 0.0 0.5 0.1 0.4 0.1 0.0 0.0 1.3 0.1 0.2 0.1 0.9 0.6 0.3 0.0 0.8 0.0 124.9 4.3 0.4 1.2 3.1 0.4 1.5 0.3 2.6 21.6 0.7 3.2 3.3 6.0 17.7 0.7 3.5 3.6 12.8 1.6 2.7 0.5 0.6 0.9 3.7 0.8 1.1 0.6 0.8 0.7 0.8 1.8 1.1 1.1 0.9 1.2 1.4 1.4 3.2 1.7 1.6 29.2 0.9 0.6 0.5 0.6 0.0 0.6 0.6 11.7 0.0 0.4 0.0 0.0 0.2 19.1 2.0 0.0 0.4 0.3 2.4 1.0 1.8 0.0 3.0 0.3 0.6 0.5 1.9 8.2 0.8 0.0 1.2 1.4 1.0 2.0 0.0 0.4 1.4 0.0 4.8 2.3 0.0 0.3 5.6 0.0 3.7 5.2 0.0 51.5 0.5 1.3 0.4 0.3 0.0 15.7 0.6 2.2 0.4 8.5 0.0 0.0 1.0 2.6 0.1 0.4 1.4 0.9 0.3 29.8 1.8 0.9 1.3 PAX1 ENSG00000125813 "Paired box 1" P15863 20 21705659-21718486 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "parathyroid gland: 162.1" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 7.7" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "SCLC-21H: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (9.74e-2)" "unprognostic (3.45e-2)" "unprognostic (3.01e-1)" "unprognostic (2.64e-2)" "unprognostic (1.04e-2)" "unprognostic (2.33e-2)" "unprognostic (4.04e-2)" "unprognostic (2.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.36e-1)" "unprognostic (8.08e-2)" 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 162.1 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.1 0.9 0.0 19.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.5 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 PAX2 ENSG00000075891 "Paired box 2" Q02962 10 100735396-100829944 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 29.6;kidney: 85.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 145.3;Distal tubular cells: 49.0;Endometrial ciliated cells: 129.5;Glandular and luminal cells: 246.0" "Group enriched" "Detected in some" 19 "endometrial cancer: 6.7;ovarian cancer: 7.0;renal cancer: 14.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "AN3-CA: 14.4;EFO-21: 22.6;RPTEC TERT1: 16.0" "Group enriched" "Detected in some" 9 "cerebellum: 1.3;pons and medulla: 3.4" "Group enriched" "Detected in some" 7 "cerebellum: 3.6;medulla oblongata: 5.6;spinal cord: 4.9" "CAB013024, HPA047704, HPA070751" Enhanced Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB013024: AB_2533990, HPA047704: AB_2636861, HPA070751: AB_2686305" "unprognostic (3.98e-2)" "unprognostic (9.55e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (4.85e-2)" "unprognostic (5.54e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-1)" "unprognostic (1.24e-2)" "unprognostic (6.59e-2)" "unprognostic (9.18e-2)" "unprognostic (3.30e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-1)" "unprognostic (6.34e-2)" "unprognostic (8.26e-2)" 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.2 0.4 5.4 0.2 0.0 0.0 1.8 29.6 0.0 8.4 0.0 0.0 0.5 0.4 85.3 0.1 0.0 0.0 6.8 1.6 0.2 0.4 5.9 0.8 0.0 3.3 0.2 0.0 1.2 0.0 11.5 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 14.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 22.6 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 16.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 2.2 0.4 0.5 0.4 6.8 1.6 3.3 6.3 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.4 5.9 0.0 0.0 145.3 0.0 0.0 0.0 0.0 49.0 0.0 9.4 129.5 14.8 0.6 0.0 0.0 0.5 0.2 0.0 0.2 0.0 246.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.5 0.0 1.1 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 27.6 0.0 0.5 0.0 0.0 0.6 1.1 1.2 0.0 0.0 0.0 1.2 0.0 0.1 0.0 PAX4 MODY9 ENSG00000106331 "Paired box 4" O43316 7 127610292-127618142 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "intestine: 1.0" "Cell type enriched" "Detected in some" 7 "Enteroendocrine cells: 85.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 49 "SCLC-21H: 10.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "unprognostic (1.52e-1)" "unprognostic (9.71e-2)" "unprognostic (4.86e-3)" "unprognostic (1.21e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 2.9 0.0 0.0 0.0 85.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 PBX1 ENSG00000185630 "PBX homeobox 1" P40424 1 164555584-164899296 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Steroidogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 382.3;Excitatory neurons: 475.9;Inhibitory neurons: 405.0;Oligodendrocyte precursor cells: 327.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 93.0;NTERA-2: 111.5;SK-BR-3: 186.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003505, HPA003881, CAB018768" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB018768: AB_675783, HPA003505: AB_1855019, HPA003881: AB_1855020" "unprognostic (2.26e-2)" "unprognostic (1.95e-1)" "unprognostic (9.09e-2)" "unprognostic (2.14e-2)" "unprognostic (5.21e-3)" "unprognostic (6.94e-3)" "unprognostic (5.95e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "unprognostic (2.24e-3)" "unprognostic (2.30e-1)" "unprognostic (8.81e-2)" "unprognostic (1.34e-2)" "unprognostic (2.13e-1)" "unprognostic (5.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.25e-1)" 24.3 32.1 16.5 11.8 22.3 3.1 36.1 10.7 18.0 88.3 1.9 52.3 22.4 136.8 21.6 30.1 74.6 37.6 24.0 15.3 14.1 29.4 7.7 20.7 4.5 8.8 32.7 52.1 48.1 29.5 14.3 19.5 6.7 38.0 19.8 17.1 43.8 53.8 36.3 10.2 19.9 125.2 13.7 10.2 21.9 6.8 12.6 10.9 35.1 26.5 8.1 40.2 41.5 12.1 2.9 74.4 82.4 19.1 50.8 23.3 3.4 25.2 20.9 8.4 6.1 14.2 11.8 0.0 5.5 47.8 4.3 22.8 31.7 8.1 3.6 3.1 31.3 93.0 56.5 0.3 34.7 0.0 22.2 24.4 0.0 5.4 2.1 19.2 0.3 0.0 0.2 0.0 2.2 47.1 0.2 0.6 111.5 3.8 4.5 0.0 21.6 27.0 6.3 44.1 2.5 39.6 27.8 186.1 0.1 71.4 73.2 0.0 0.5 3.7 8.6 24.2 8.1 8.5 61.2 0.1 0.4 0.2 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 16.5 22.3 10.7 18.0 15.3 14.1 8.8 32.7 6.7 13.7 12.6 12.1 28.6 22.4 18.6 382.3 2.8 22.8 115.0 39.8 70.6 39.9 129.9 87.8 50.0 98.7 25.3 33.1 110.5 101.3 1.5 29.2 33.2 47.9 91.3 47.7 144.3 47.0 90.9 30.3 475.9 68.7 7.3 126.7 32.1 38.5 71.7 57.6 68.9 18.7 9.7 5.0 405.0 38.2 50.8 1.9 17.5 124.4 63.6 12.1 16.0 125.5 1.6 33.5 1.0 327.2 227.4 31.7 72.5 103.8 2.8 41.5 40.4 57.9 37.3 30.6 39.5 142.0 70.9 2.3 17.5 83.6 28.1 104.7 7.6 168.0 43.7 75.9 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 201.9;Late spermatids: 53.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 60.9 23.7 35.7 2.9 35.5 3.5 28.4 36.6 35.8 3.7 17.5 4.7 6.5 3.8 1.8 9.3 3.2 2.8 4.3 32.4 41.0 23.3 148.0 2.6 1.3 43.4 40.1 5.1 4.9 18.2 8.6 4.4 37.6 7.2 2.8 2.4 35.3 9.3 12.1 4.7 7.7 1.4 37.8 1.5 9.1 10.7 49.0 2.0 4.6 6.6 2.0 2.9 4.4 37.0 6.1 19.3 6.5 17.2 25.4 8.9 6.6 3.4 15.5 6.9 7.5 8.8 6.0 0.0 7.4 6.0 9.6 6.8 7.7 39.5 1.5 2.8 11.0 10.3 57.4 41.2 21.0 0.1 10.8 40.2 10.1 5.8 12.4 4.4 5.7 14.3 17.4 0.0 2.1 44.6 9.2 4.6 12.0 15.1 16.2 8.3 13.0 3.2 5.7 1.9 15.2 21.0 33.6 18.0 15.5 4.8 14.6 2.7 6.3 7.8 6.6 8.8 4.7 3.5 4.8 0.1 7.7 5.7 6.7 0.0 1.3 0.0 0.5 0.3 0.5 0.0 0.1 0.5 0.9 0.2 0.9 0.5 0.1 0.1 0.1 0.3 0.5 0.7 35.7 35.5 36.6 35.8 32.4 41.0 43.4 40.1 37.6 37.8 49.0 37.0 0.9 0.0 3.0 26.4 1.4 1.3 1.6 9.1 2.8 5.6 4.8 5.8 4.4 11.5 3.0 3.7 2.1 17.4 0.6 27.6 1.9 3.1 18.4 2.3 7.1 1.5 9.0 28.0 18.5 1.8 4.2 3.2 5.6 3.0 8.9 16.0 4.6 201.9 12.3 0.0 18.6 5.0 0.0 7.0 1.8 53.2 0.6 1.8 5.4 7.5 18.9 9.4 2.1 10.1 16.7 2.3 8.5 4.1 0.1 3.1 23.6 39.0 1.5 4.8 0.0 2.2 2.2 11.2 4.7 4.1 0.6 25.4 1.2 6.0 6.4 1.3 PCDH1 pc42 ENSG00000156453 "Protocadherin 1" Q08174 5 141853090-141879246 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 61.5;Distal enterocytes: 66.4;Exocrine glandular cells: 46.3;Pancreatic endocrine cells: 65.2;Urothelial cells: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 86.1;HaCaT: 108.0;HUVEC TERT2: 56.2;OE19: 77.8;RT4: 74.2;TIME: 74.5;WM-115: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047720, HPA050538" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA 2500000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cell Junctions" Nucleoli "HPA047720: AB_2680130, HPA050538: AB_2681162" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (5.30e-2)" "unprognostic (4.61e-3)" "unprognostic (5.03e-2)" "unprognostic (4.16e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (1.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.43e-1)" "prognostic favorable (7.55e-5)" "unprognostic (2.05e-1)" "unprognostic (4.16e-2)" "unprognostic (3.13e-2)" "unprognostic (1.91e-1)" 24.0 4.0 11.7 7.7 15.9 1.2 22.8 3.3 15.1 11.6 0.0 23.1 21.4 9.2 6.4 41.7 9.1 6.6 19.3 17.0 2.3 21.3 19.3 27.7 2.0 0.0 0.8 2.5 13.8 3.8 6.5 19.2 0.0 10.8 14.3 3.4 28.8 11.2 8.2 27.4 17.1 7.2 1.1 1.8 23.6 1.1 2.7 1.0 12.6 11.1 9.1 9.8 19.2 5.7 18.9 1.0 7.7 8.5 0.3 0.0 5.5 0.2 0.2 0.1 0.0 4.5 86.1 0.1 43.7 0.6 1.0 108.0 9.9 7.9 0.0 0.1 0.3 0.0 0.4 0.1 6.9 0.0 0.3 0.0 17.8 0.1 1.2 18.1 56.2 0.0 0.1 9.2 0.0 15.1 0.3 0.0 32.5 77.8 14.6 0.3 0.1 13.2 6.3 74.2 0.9 1.8 0.5 23.3 20.0 21.6 18.8 0.4 74.5 0.1 0.7 0.1 6.9 0.0 0.1 0.2 0.5 0.0 52.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 11.7 15.9 3.3 15.1 17.0 2.3 0.0 0.8 0.0 1.1 2.7 5.7 61.5 0.0 5.3 3.6 0.2 1.0 12.0 4.6 0.0 9.6 9.5 4.7 4.4 20.0 8.6 12.9 0.0 0.7 2.0 66.4 3.9 15.3 1.3 10.1 2.1 34.2 7.7 2.7 12.3 46.3 0.3 2.6 21.9 21.3 0.0 0.0 7.5 30.1 0.2 26.9 6.1 21.3 12.2 1.4 2.3 2.5 0.6 0.5 0.0 6.5 0.0 4.8 7.2 5.5 7.2 65.2 30.3 0.4 1.4 25.8 36.4 5.2 7.1 0.5 13.1 0.9 18.5 0.3 0.2 7.4 2.6 20.1 0.9 0.5 18.9 54.5 PCDH11Y "PCDH22, PCDHY" ENSG00000099715 "Protocadherin 11 Y-linked" Q9BZA8 Y 5000226-5742224 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 4.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 29.1;Excitatory neurons: 52.9;Horizontal cells: 47.1;Inhibitory neurons: 88.1;Oligodendrocyte precursor cells: 54.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (9.26e-2)" "unprognostic (1.84e-1)" "unprognostic (7.64e-3)" "unprognostic (2.36e-2)" "unprognostic (3.55e-2)" 0.0 0.0 3.8 0.1 4.7 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 3.4 0.1 0.0 0.0 0.0 2.1 2.3 0.0 0.0 0.0 0.0 0.5 1.7 0.1 0.2 0.8 0.0 0.5 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.8 4.7 0.0 4.6 2.3 3.4 2.1 2.3 1.7 0.7 0.4 0.9 0.3 6.4 29.1 1.6 0.5 1.8 1.0 0.0 0.6 3.0 0.3 0.0 0.6 0.0 13.6 14.7 0.0 5.2 0.0 0.1 0.0 0.0 0.3 0.5 0.2 3.9 0.0 0.0 52.9 0.0 0.3 2.7 0.0 0.5 18.9 0.1 3.6 0.0 0.3 47.1 88.1 0.2 2.0 0.0 4.8 0.1 0.3 2.7 0.0 21.5 0.0 0.3 0.0 54.8 4.4 0.1 0.0 0.0 0.4 0.9 0.0 0.7 9.5 3.6 0.0 1.2 0.4 0.3 2.0 0.2 1.6 2.2 2.5 0.0 0.0 1.5 PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 4 "Adipocytes: 38.5;Endothelial cells: 40.0;Hepatic stellate cells: 41.0;Hofbauer cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 25.9;Karpas-707: 66.5;U-937: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" 13.4 5.0 0.8 2.5 0.9 0.5 4.9 2.5 1.7 2.7 1.2 2.0 2.0 2.8 0.4 2.1 2.1 4.0 10.8 0.6 0.8 6.0 4.0 15.5 2.6 0.5 0.3 1.7 1.4 2.9 3.6 30.2 0.6 1.9 1.3 1.6 1.4 2.3 4.0 1.7 2.1 5.2 0.3 18.6 2.0 1.1 1.4 0.8 6.5 5.1 1.0 3.2 1.9 0.3 0.1 0.1 1.9 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 5.0 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.6 1.4 0.2 0.1 0.2 0.5 0.2 0.0 0.0 0.4 0.0 0.4 25.9 0.3 0.0 66.5 0.0 0.4 0.1 0.3 0.5 0.0 0.3 0.5 0.2 3.0 0.0 0.1 0.3 0.7 0.1 0.1 0.3 0.2 0.0 1.8 1.8 0.6 0.1 0.9 0.1 0.4 0.4 0.1 0.4 11.7 2.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.8 0.9 2.5 1.7 0.6 0.8 0.5 0.3 0.6 0.3 1.4 0.3 38.5 0.0 1.1 0.0 0.5 0.6 0.0 0.0 1.2 1.3 0.1 0.1 4.0 0.0 0.0 0.0 2.1 0.3 0.3 0.0 3.9 0.1 1.7 0.1 0.1 40.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.1 1.3 0.0 41.0 0.5 34.6 0.0 0.2 0.0 0.0 8.5 0.3 2.5 0.0 1.5 1.8 6.5 0.3 0.5 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.2 0.3 0.5 0.2 1.4 0.0 0.2 PCDH15 "CDHR15, DFNB23, USH1F" ENSG00000150275 "Protocadherin related 15" Q96QU1 10 53802771-55627942 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 19.0;brain: 21.2;retina: 61.7" "Cell type enriched" "Detected in some" 13 "Oligodendrocyte precursor cells: 2965.2" "Cancer enriched" "Detected in single" 9 "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-2 OS: 1.1;U-266/70: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074437 Supported "Intracellular and membrane" NA NA 22000 "Cluster 77: Retina - Visual perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" "HPA074437: " "unprognostic (1.38e-1)" "unprognostic (3.39e-1)" "unprognostic (8.15e-5)" "unprognostic (3.07e-3)" "unprognostic (2.79e-1)" "unprognostic (9.15e-4)" "unprognostic (2.02e-1)" "unprognostic (3.89e-2)" "unprognostic (1.12e-3)" "unprognostic (1.31e-3)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (7.66e-3)" 0.2 19.0 13.4 0.3 9.5 0.1 0.0 3.1 10.3 0.2 0.0 0.1 0.2 0.1 0.5 0.1 0.1 0.1 0.5 16.6 19.6 8.0 0.0 2.5 0.4 13.8 13.7 0.0 0.0 0.5 4.7 0.2 12.6 0.2 0.0 61.7 0.1 0.0 0.0 0.1 0.2 0.0 9.7 0.7 0.3 3.3 21.2 0.1 0.0 0.0 0.5 0.5 0.0 6.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 1.1 0.0 0.0 3.3 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 9.5 3.1 10.3 16.6 19.6 13.8 13.7 12.6 9.7 21.2 6.2 0.0 0.0 0.0 14.4 0.0 0.3 0.0 0.0 0.0 5.1 0.6 0.0 4.8 0.0 0.0 0.0 87.6 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.1 0.3 0.0 0.0 27.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 216.2 0.1 0.0 0.0 0.0 7.5 0.0 0.1 0.0 3.7 0.0 4.4 0.0 2965.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 92.8 0.0 0.0 0.2 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 PCDHA1 ENSG00000204970 "Protocadherin alpha 1" Q9Y5I3 5 140786136-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9;pituitary gland: 1.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 2.2;Hepatic stellate cells: 1.4;Sertoli cells: 6.6;Spermatogonia: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "T-47d: 9.1" "Low region specificity" "Detected in many" HPA035969 Enhanced Approved "Plasma membrane" "Secreted - unknown location" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA035969: AB_10673492" "unprognostic (2.76e-5)" "unprognostic (1.19e-1)" "unprognostic (3.74e-2)" "unprognostic (1.09e-4)" "unprognostic (7.38e-2)" "unprognostic (2.86e-2)" "unprognostic (2.26e-3)" "unprognostic (1.25e-2)" "unprognostic (1.91e-2)" "unprognostic (1.81e-1)" "unprognostic (9.01e-5)" "unprognostic (2.46e-2)" "unprognostic (1.91e-1)" "unprognostic (7.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (1.29e-1)" 0.0 0.2 0.2 0.0 0.5 0.0 0.1 1.5 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.1 0.0 0.0 0.0 1.5 0.7 0.0 0.1 0.0 1.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.1 1.1 0.1 9.1 0.3 0.0 1.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.5 1.0 0.7 0.4 1.5 0.7 1.1 0.9 0.5 1.9 0.0 3.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHA10 "CNR8, CNRN8, CNRS8, CRNR8, PCDH-ALPHA10" ENSG00000250120 "Protocadherin alpha 10" Q9Y5I2 5 140855883-141012347 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.3;pancreas: 4.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.3;Cone photoreceptor cells: 8.4;Horizontal cells: 8.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 16.2" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (4.24e-2)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (4.70e-2)" "unprognostic (4.19e-1)" "unprognostic (2.36e-1)" "unprognostic (6.46e-2)" "unprognostic (8.24e-2)" "unprognostic (8.10e-2)" "unprognostic (5.28e-2)" "unprognostic (2.65e-1)" "unprognostic (6.14e-3)" "unprognostic (1.93e-2)" "unprognostic (3.57e-3)" "unprognostic (5.21e-2)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" 0.8 0.5 1.3 0.3 1.8 0.1 0.7 6.3 2.4 0.9 0.0 0.2 0.3 1.8 2.0 0.0 1.0 1.2 0.1 1.6 0.7 1.5 0.0 0.8 0.2 2.1 1.0 1.1 4.1 0.7 1.5 0.0 2.0 0.4 0.1 2.4 0.5 0.2 0.1 0.1 0.7 1.6 1.5 0.1 0.3 1.3 1.1 0.0 2.1 0.1 0.0 0.2 0.1 2.7 0.0 0.2 0.5 3.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 16.2 0.2 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.3 1.2 0.8 0.0 0.1 0.0 2.4 0.3 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.8 6.3 2.4 1.6 0.7 2.1 1.0 2.0 1.5 1.1 2.7 0.9 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 7.3 1.2 1.4 0.6 1.5 0.1 0.0 8.4 0.0 0.0 0.2 0.0 0.2 3.2 0.6 2.7 0.6 1.8 0.0 0.0 0.9 0.0 0.6 0.0 0.5 0.0 0.3 0.4 0.0 0.0 8.4 0.0 0.0 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.9 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 3.2 0.0 2.5 2.3 2.2 0.3 0.0 0.0 0.0 0.2 0.3 0.1 0.3 PCDHA11 "CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11" ENSG00000249158 "Protocadherin alpha 11" Q9Y5I1 5 140868183-141012347 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;parathyroid gland: 2.7;retina: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.0;AN3-CA: 10.7;EFO-21: 7.6;MCF7: 4.4;T-47d: 6.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077160 Approved "Vesicles,Cell Junctions,Cytoplasmic bodies" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cell Junctions" "Cytoplasmic bodies" "HPA077160: AB_2686827" "unprognostic (1.54e-2)" "unprognostic (1.83e-3)" "unprognostic (2.75e-1)" "unprognostic (2.59e-1)" "unprognostic (6.98e-3)" "unprognostic (1.36e-1)" "unprognostic (9.28e-3)" "unprognostic (2.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.53e-2)" "unprognostic (2.27e-2)" "unprognostic (3.13e-4)" "unprognostic (9.91e-5)" "unprognostic (1.05e-1)" "unprognostic (3.85e-3)" "unprognostic (3.26e-2)" 0.2 0.3 1.5 0.1 1.3 0.0 0.2 4.2 2.2 0.8 0.0 0.1 0.0 0.5 0.1 0.0 0.2 0.8 0.0 1.1 0.3 0.7 0.1 0.4 0.1 0.0 1.5 0.0 1.8 2.7 1.0 0.0 0.3 0.1 0.0 2.4 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.0 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.7 0.0 2.1 4.0 10.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.6 0.0 0.8 0.0 0.1 1.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.4 0.3 0.0 1.0 0.0 0.1 0.0 4.4 0.0 0.0 3.5 0.8 2.8 0.0 0.0 0.0 0.4 1.6 0.2 1.9 0.0 1.9 0.4 1.9 6.5 0.0 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 4.2 2.2 1.1 0.3 0.0 1.5 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHA6 "CNR2, CNRS2, CRNR2, PCDH-ALPHA6" ENSG00000081842 "Protocadherin alpha 6" Q9UN73 5 140827958-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.0;EFO-21: 8.4;hTERT-RPE1: 2.2;U-2 OS: 3.4;WM-115: 5.2" "Low region specificity" "Detected in many" "HPA059326, HPA078110" Enhanced Approved Vesicles "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 38: EFO-21 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA059326: AB_2683980, HPA078110: AB_2732371" "unprognostic (1.15e-1)" "unprognostic (7.00e-2)" "unprognostic (5.07e-1)" "unprognostic (2.79e-1)" "unprognostic (4.39e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-4)" "unprognostic (4.23e-3)" "unprognostic (8.38e-2)" "unprognostic (2.55e-1)" "unprognostic (1.23e-3)" "unprognostic (3.44e-1)" "unprognostic (1.03e-2)" "unprognostic (2.66e-3)" "unprognostic (2.56e-1)" "unprognostic (5.66e-3)" "unprognostic (3.55e-2)" 0.2 0.3 0.8 0.1 0.9 0.0 0.3 4.1 1.1 0.4 0.0 0.1 0.2 0.6 0.3 0.0 0.3 0.3 0.1 1.0 0.7 0.4 0.0 0.2 0.1 0.4 0.3 0.4 1.0 1.5 1.5 0.0 0.5 0.2 0.0 1.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.1 2.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.5 1.0 0.1 0.4 0.0 1.3 0.0 3.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 4.1 1.1 1.0 0.7 0.4 0.3 0.5 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHB12 PCDH-BETA12 ENSG00000120328 "Protocadherin beta 12" Q9Y5F1 5 141208697-141212571 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.0;Endometrial stromal cells: 2.8;Fibroblasts: 2.8;Melanocytes: 3.6;Peritubular cells: 2.6;Skeletal myocytes: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.7;ASC diff: 2.5;EFO-21: 3.0;RH-30: 3.2;U-2 OS: 2.3;U-2197: 2.4" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.43e-2)" "unprognostic (3.22e-3)" "unprognostic (4.18e-3)" "unprognostic (8.43e-2)" "unprognostic (3.95e-3)" "unprognostic (7.87e-3)" "unprognostic (1.46e-1)" "unprognostic (2.95e-2)" "unprognostic (3.63e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (2.94e-2)" "unprognostic (4.37e-3)" "unprognostic (3.22e-3)" "unprognostic (4.97e-3)" "unprognostic (3.83e-2)" "unprognostic (6.41e-3)" 1.3 0.6 0.1 0.4 0.7 0.0 1.2 0.9 1.1 1.9 0.0 1.3 0.2 2.7 0.8 0.4 1.9 1.0 1.4 0.8 0.1 0.6 0.3 1.4 0.1 0.3 0.3 2.2 1.3 1.0 2.0 0.4 0.0 0.9 0.4 0.8 0.6 0.9 0.7 0.5 0.6 1.8 0.1 0.7 0.6 1.1 0.1 0.1 0.6 0.9 0.1 1.2 1.1 0.7 0.0 0.0 0.7 2.7 2.5 1.4 0.4 0.0 1.9 0.1 0.2 0.0 0.0 0.0 3.0 0.3 1.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.7 0.2 0.0 0.0 0.6 0.7 0.1 0.0 0.0 0.1 0.0 0.5 0.5 3.2 0.0 0.0 0.0 1.5 0.9 0.0 0.0 0.6 0.2 2.1 0.4 0.2 0.4 2.3 2.4 0.0 0.0 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.9 1.1 0.8 0.1 0.3 0.3 0.0 0.1 0.1 0.7 1.9 0.0 1.1 0.0 0.0 0.4 0.0 0.2 0.0 4.0 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.8 0.1 2.8 1.3 1.8 0.0 0.0 0.9 0.0 2.8 0.5 0.1 0.0 0.1 1.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.0 3.6 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.1 0.0 0.2 0.0 0.3 0.0 2.2 1.6 1.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 "Protocadherin gamma subfamily A, 11" Q9Y5H2 5 141421047-141512975 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Bipolar cells: 2.5;Hepatic stellate cells: 1.1;Horizontal cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.3;ASC TERT1: 25.9;GAMG: 47.4;hTERT-RPE1: 69.8;WM-115: 43.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.13e-2)" "unprognostic (1.78e-3)" "unprognostic (9.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.68e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.16e-3)" "unprognostic (1.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.97e-1)" "unprognostic (2.22e-1)" "unprognostic (3.03e-2)" "unprognostic (3.74e-2)" "unprognostic (3.54e-1)" "unprognostic (4.34e-3)" "unprognostic (1.89e-1)" 0.8 0.7 1.4 0.7 1.8 0.0 0.6 5.1 1.3 0.8 0.7 1.0 0.2 0.7 0.3 0.7 0.9 0.5 1.6 2.1 2.3 0.5 0.4 0.6 0.4 1.8 1.2 1.1 0.5 0.3 0.6 2.2 2.1 0.5 0.3 3.1 0.7 0.7 1.1 1.7 0.4 0.8 2.4 0.3 0.4 0.8 1.9 0.3 0.8 0.5 0.3 0.6 0.8 2.9 0.0 0.0 0.7 2.4 24.3 25.9 0.9 5.5 10.6 4.2 6.6 0.1 0.2 0.6 9.1 5.6 47.4 3.7 0.1 0.6 6.6 0.2 2.4 0.1 0.1 0.0 4.0 0.4 0.0 19.0 0.3 7.4 0.1 69.8 6.5 1.2 0.0 0.1 0.1 0.0 0.0 0.3 2.9 0.0 0.1 17.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 21.3 9.9 0.5 3.2 7.9 0.8 0.1 0.6 0.1 0.0 0.4 0.0 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 1.8 5.1 1.3 2.1 2.3 1.8 1.2 2.1 2.4 1.9 2.9 0.5 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 2.5 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.1 0.5 0.8 0.0 0.0 0.0 0.2 0.3 0.5 0.0 0.1 0.0 0.2 1.1 0.0 0.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.6 0.3 0.1 0.1 0.7 0.0 0.1 0.0 0.2 0.1 0.1 PCF11 KIAA0824 ENSG00000165494 "PCF11 cleavage and polyadenylation factor subunit" O94913 11 83156988-83187451 "Plasma proteins, Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 227.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 124.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040779 Supported Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Mitochondria "HPA040779: AB_2677133" "unprognostic (1.53e-1)" "unprognostic (7.24e-2)" "unprognostic (3.99e-2)" "unprognostic (1.18e-1)" "unprognostic (3.24e-3)" "prognostic favorable (1.34e-4)" "unprognostic (3.74e-2)" "unprognostic (4.89e-3)" "unprognostic (1.12e-3)" "unprognostic (9.53e-2)" "unprognostic (6.07e-2)" "unprognostic (5.63e-2)" "unprognostic (1.55e-1)" "unprognostic (3.91e-3)" "unprognostic (1.15e-1)" "unprognostic (1.07e-1)" "prognostic favorable (2.03e-5)" 20.1 13.9 9.8 23.5 15.0 42.5 23.7 29.1 13.6 19.2 6.0 19.6 16.3 22.4 15.2 19.5 17.7 17.2 13.5 9.3 10.9 14.9 16.9 22.8 32.4 13.1 12.7 28.3 17.0 16.6 10.4 16.7 14.0 18.7 19.9 26.6 15.4 16.2 26.3 27.8 20.8 23.8 10.9 28.7 16.4 24.7 12.1 33.4 24.3 19.5 29.6 17.0 13.5 17.9 26.3 18.4 29.4 25.3 34.4 33.4 23.5 24.7 18.2 23.2 17.7 31.5 25.7 58.9 18.1 18.0 21.9 25.8 43.2 17.0 22.3 42.1 14.8 34.5 26.3 22.4 19.4 40.9 36.8 23.9 32.1 17.7 25.6 31.2 23.8 38.8 40.9 27.9 21.9 27.9 38.7 45.2 30.7 44.6 20.5 36.4 37.1 35.2 20.2 38.4 24.4 27.0 30.1 23.7 24.3 26.9 23.7 28.0 24.6 33.0 16.9 24.5 16.6 25.0 45.2 124.6 14.5 26.8 26.0 14.8 7.2 14.9 10.1 6.8 8.5 10.9 6.9 7.3 6.9 9.9 7.8 8.2 17.1 13.5 5.5 7.1 5.5 5.8 9.8 15.0 29.1 13.6 9.3 10.9 13.1 12.7 14.0 10.9 12.1 17.9 96.4 41.7 63.5 58.1 90.6 53.7 79.8 30.7 101.9 48.4 84.4 81.0 42.7 35.8 43.4 46.0 33.3 30.2 90.1 49.8 25.4 22.9 203.3 55.5 70.8 66.8 31.8 62.5 32.0 18.1 26.9 58.8 40.2 83.6 37.2 48.0 56.7 21.7 37.6 55.5 37.9 51.0 26.4 57.8 41.0 40.3 60.3 87.4 28.4 45.0 52.5 34.5 58.7 40.7 72.0 19.2 46.2 45.1 69.0 71.6 83.4 14.2 29.0 55.3 39.5 227.3 66.8 46.7 17.9 100.4 62.7 39.4 81.7 42.7 50.3 71.1 PCGF2 "MEL-18, RNF110, ZNF144" ENSG00000277258 "Polycomb group ring finger 2" P35227 17 38733898-38749817 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047732, HPA063531" Uncertain Supported Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA047732: AB_2680138, HPA063531: AB_2685031" "unprognostic (1.56e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (4.55e-4)" "unprognostic (2.45e-1)" "unprognostic (1.37e-1)" "unprognostic (1.31e-3)" "unprognostic (2.47e-2)" "unprognostic (7.78e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (5.10e-3)" "unprognostic (8.18e-2)" "unprognostic (6.12e-2)" "unprognostic (7.66e-2)" "unprognostic (2.42e-1)" "unprognostic (1.00e-2)" "unprognostic (1.79e-1)" 33.6 38.3 3.3 4.6 3.2 0.0 33.0 7.7 5.5 44.7 4.3 24.4 3.7 40.6 2.4 21.4 35.9 6.1 37.3 3.2 5.2 56.5 12.9 33.4 2.1 2.6 3.0 40.5 22.9 2.9 55.6 6.8 2.9 37.5 1.6 7.2 22.6 2.7 9.3 21.6 22.7 2.1 1.2 28.3 25.3 13.3 4.1 0.2 41.7 0.9 0.8 27.3 30.8 3.1 16.9 38.2 9.2 34.5 7.2 2.3 11.7 13.1 6.2 6.2 7.4 21.1 17.6 1.3 14.3 4.2 16.3 26.2 3.4 6.1 2.5 10.4 20.1 7.9 20.7 52.4 2.3 1.2 9.4 2.5 2.8 9.0 6.1 9.6 7.5 7.9 14.9 21.2 3.9 37.8 1.5 0.2 11.7 7.4 15.3 12.6 14.7 3.3 3.2 22.5 16.4 26.8 12.6 9.0 20.8 9.0 35.4 1.6 22.0 24.8 27.1 24.8 23.2 12.5 4.1 4.3 13.3 2.0 22.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.2 7.7 5.5 3.2 5.2 2.6 3.0 2.9 1.2 4.1 3.1 49.6 3.2 16.0 2.0 1.1 14.1 11.2 19.7 23.9 59.9 20.6 17.0 2.1 15.7 10.1 20.2 10.4 13.3 0.8 23.7 52.8 24.9 15.1 8.0 22.1 46.4 13.2 0.0 6.5 13.7 26.7 21.9 12.8 12.8 1.3 14.0 51.0 2.9 4.8 35.3 7.0 12.5 22.4 2.9 5.5 5.0 37.0 2.9 14.2 6.5 3.2 26.4 2.1 9.5 2.4 18.9 10.3 29.3 3.8 15.4 22.3 59.6 5.0 16.5 0.0 16.8 16.7 6.1 15.7 9.6 16.9 22.2 0.9 13.3 13.2 11.1 PCGF3 "DONG1, FLJ36550, MGC40413, RNF3, RNF3A" ENSG00000185619 "Polycomb group ring finger 3" Q3KNV8 4 705748-770640 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061879 Approved Supported Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA061879: AB_2684631" "unprognostic (1.24e-1)" "unprognostic (2.77e-1)" "unprognostic (2.62e-1)" "unprognostic (1.06e-2)" "unprognostic (1.66e-1)" "prognostic favorable (3.73e-4)" "unprognostic (2.76e-2)" "unprognostic (4.21e-2)" "unprognostic (9.52e-2)" "unprognostic (1.47e-2)" "prognostic favorable (1.44e-4)" "unprognostic (2.36e-2)" "unprognostic (6.84e-3)" "unprognostic (2.53e-1)" "unprognostic (2.20e-1)" "unprognostic (1.96e-1)" "prognostic favorable (5.25e-4)" 32.7 45.1 17.9 15.5 18.5 30.1 34.7 30.6 19.5 41.9 16.7 31.7 22.6 35.3 8.7 35.5 33.6 14.0 27.2 18.9 17.0 31.7 29.7 34.7 18.3 18.1 17.2 50.4 27.8 7.8 31.4 19.8 17.5 38.3 10.3 13.3 37.4 9.7 18.4 53.3 36.2 10.7 16.2 51.0 32.1 23.3 17.9 18.6 34.6 11.4 11.8 27.2 39.4 24.1 22.1 19.6 35.3 40.4 15.8 16.2 43.3 29.2 15.9 23.5 23.7 21.5 23.8 15.7 19.1 28.3 23.8 14.9 16.5 23.7 17.8 20.8 17.9 22.6 24.2 38.4 19.3 15.5 28.9 20.5 31.0 20.5 9.3 15.4 30.5 28.2 31.5 12.6 23.3 24.6 41.8 54.6 23.4 14.9 35.0 41.0 22.4 10.1 14.1 35.6 50.2 37.9 15.2 16.1 16.1 22.7 31.5 21.8 36.9 22.8 18.4 19.2 38.1 30.1 27.6 24.6 18.0 24.5 43.0 3.4 7.1 3.1 3.3 5.1 2.8 4.2 2.0 2.1 3.2 5.0 2.5 1.7 4.5 4.7 2.2 4.6 3.3 2.3 17.9 18.5 30.6 19.5 18.9 17.0 18.1 17.2 17.5 16.2 17.9 24.1 29.5 12.8 28.8 19.6 12.5 25.4 17.3 17.2 25.0 12.3 28.3 21.3 21.7 17.2 21.8 9.2 12.5 13.4 13.5 21.4 3.9 20.6 52.0 17.7 28.7 27.8 19.2 9.1 18.1 19.8 30.0 17.8 35.2 21.2 16.5 22.4 25.4 15.3 12.2 6.7 18.6 21.7 20.3 15.1 21.0 54.4 16.4 20.1 23.2 23.4 14.3 9.1 16.5 27.2 22.8 32.7 19.3 15.4 22.9 24.0 19.1 9.4 14.0 8.5 6.6 18.8 18.8 19.0 25.6 22.5 28.7 23.7 13.3 20.8 20.2 38.2 PCNX1 "KIAA0805, KIAA0995, PCNX, PCNXL1, pecanex" ENSG00000100731 "Pecanex 1" Q96RV3 14 70907405-71115382 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 31.5;Alveolar cells type 2: 27.9;dendritic cells: 31.6;Endometrial stromal cells: 35.3;Granulosa cells: 57.2;Theca cells: 50.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048970, HPA053532" Approved Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA048970: , HPA053532: AB_2682180" "unprognostic (1.96e-1)" "unprognostic (2.46e-1)" "unprognostic (2.01e-1)" "unprognostic (2.62e-1)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (1.77e-1)" "unprognostic (7.41e-2)" "unprognostic (1.04e-2)" "unprognostic (4.16e-2)" "unprognostic (5.56e-2)" "prognostic favorable (4.05e-5)" "unprognostic (9.01e-3)" "unprognostic (2.90e-1)" "unprognostic (8.11e-2)" "unprognostic (7.37e-2)" 14.1 20.0 8.1 15.3 10.4 17.5 10.7 8.2 9.9 9.6 11.1 11.5 7.9 11.0 5.1 7.8 10.5 10.0 11.5 9.5 8.3 11.8 11.5 12.8 14.4 5.7 6.3 20.0 7.0 15.8 8.2 9.0 7.1 9.1 7.6 16.6 6.7 8.8 15.2 7.3 11.8 13.2 6.2 13.4 8.2 20.7 9.0 16.9 12.3 21.8 12.5 15.5 7.4 8.8 22.3 15.5 17.4 10.9 28.7 19.3 9.6 23.3 23.2 17.9 24.9 15.4 9.8 15.8 7.8 24.0 14.0 21.9 18.8 18.8 26.8 49.0 7.3 3.0 9.7 17.0 17.4 24.5 8.0 20.0 16.4 17.8 31.9 22.0 18.0 16.1 1.3 22.5 20.9 18.0 11.6 22.0 8.8 9.9 8.4 10.5 20.0 4.7 12.2 16.3 7.2 11.3 17.6 10.5 13.0 17.7 9.5 22.7 21.5 32.7 36.5 10.7 17.1 13.5 7.4 13.4 20.2 19.7 11.6 3.3 1.8 1.7 3.4 1.0 4.6 1.3 5.9 3.6 0.4 2.8 2.5 4.0 9.8 1.9 0.7 3.7 10.3 1.7 8.1 10.4 8.2 9.9 9.5 8.3 5.7 6.3 7.1 6.2 9.0 8.8 31.5 16.0 27.9 0.0 8.3 0.0 0.0 0.0 0.0 0.0 11.4 19.7 0.0 0.0 6.2 9.2 0.0 5.9 31.6 0.0 1.9 8.2 0.0 14.1 35.3 9.2 0.0 0.0 0.0 5.3 6.9 9.6 0.0 14.1 15.2 57.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 8.4 0.0 0.0 24.3 0.0 0.0 7.5 9.5 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 5.1 24.0 50.0 0.0 0.0 PCNX4 "C14orf135, PCNXL4" ENSG00000126773 "Pecanex 4" Q63HM2 14 60091911-60169133 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 42.8;Endometrial ciliated cells: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002076, HPA003390" Uncertain Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA002076: AB_1078322, HPA003390: AB_2066703" "unprognostic (2.00e-1)" "unprognostic (1.45e-1)" "unprognostic (1.89e-1)" "unprognostic (9.87e-2)" "unprognostic (2.18e-1)" "unprognostic (2.94e-1)" "unprognostic (3.83e-3)" "unprognostic (2.01e-1)" "unprognostic (1.54e-1)" "unprognostic (3.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.81e-1)" "prognostic favorable (6.84e-5)" "unprognostic (2.13e-1)" "unprognostic (2.08e-1)" "unprognostic (4.14e-2)" "unprognostic (8.59e-2)" 7.8 9.2 4.1 6.3 4.8 7.4 8.1 7.0 4.4 10.1 12.1 6.3 5.0 12.5 7.1 5.6 13.1 8.3 11.1 3.9 6.1 12.3 6.7 7.2 7.1 5.0 6.0 16.3 6.5 11.4 11.9 8.5 4.7 11.7 6.7 18.2 7.1 8.5 12.3 7.4 6.1 10.2 4.9 7.4 6.2 11.0 5.7 11.6 9.7 5.7 7.0 6.6 7.8 6.2 85.2 14.3 25.2 17.3 19.2 22.2 11.1 28.5 44.1 31.2 38.3 15.0 26.1 14.8 11.6 23.7 26.0 11.1 16.6 16.2 51.7 20.8 7.9 25.0 10.1 9.7 39.7 25.0 17.7 18.5 10.2 23.0 38.3 24.3 14.9 34.8 12.5 21.2 48.2 11.5 35.9 8.0 12.7 9.7 17.4 20.9 31.8 6.4 15.8 11.7 17.9 21.8 25.5 9.2 18.2 13.4 22.7 11.1 30.7 66.4 52.8 16.7 20.5 7.1 7.4 19.6 26.1 8.5 33.2 3.4 4.1 3.3 4.8 4.3 6.5 4.1 3.4 4.2 4.4 2.8 3.7 4.4 2.1 8.4 5.2 4.4 3.8 3.4 4.1 4.8 7.0 4.4 3.9 6.1 5.0 6.0 4.7 4.9 5.7 6.2 22.3 16.0 29.9 0.0 18.2 0.0 0.0 0.0 0.0 0.0 19.9 17.5 0.0 0.0 19.2 25.8 0.0 18.3 42.8 0.0 17.6 18.4 0.0 82.0 37.4 14.0 0.0 0.0 0.0 13.1 8.3 13.6 0.0 27.0 15.2 33.9 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 10.3 0.0 0.0 0.0 0.0 20.4 0.0 0.0 18.5 0.0 0.0 14.4 34.2 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 19.4 14.5 33.8 0.0 0.0 PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 491.6;Fibroblasts: 439.9;Leydig cells: 140.5;Smooth muscle cells: 442.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 879.0;BJ hTERT+: 663.0;fHDF/TERT166: 404.5;HSkMC: 973.2;SH-SY5Y: 689.9;U-2197: 1213.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" 101.5 45.5 2.4 51.5 3.8 0.6 72.6 3.5 10.2 162.8 4.6 30.5 7.8 81.7 11.0 26.9 80.6 112.5 110.8 2.3 2.5 21.9 59.7 72.4 41.3 3.0 2.4 47.7 20.6 10.3 31.2 59.5 2.9 45.5 16.7 0.2 24.9 33.5 16.9 45.0 21.6 59.9 3.1 13.8 22.9 13.7 3.6 10.5 49.1 32.7 17.4 86.4 86.7 2.5 0.2 0.5 2.2 3.0 321.5 879.0 2.4 355.5 663.0 161.1 142.7 14.5 0.8 1.1 1.2 404.5 0.5 0.2 0.0 1.2 15.9 2.5 2.5 0.3 6.1 19.8 82.1 0.1 3.5 973.2 0.3 86.3 0.6 0.4 0.1 1.7 8.3 2.0 0.7 2.1 0.6 3.3 72.2 0.0 4.2 1.0 1.5 0.8 0.4 0.6 1.1 689.9 0.2 2.4 1.6 8.2 2.0 0.0 3.5 391.8 107.6 1213.4 0.2 0.4 0.5 0.1 136.6 1.2 68.2 0.0 0.0 0.4 0.1 0.3 0.3 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.1 0.0 2.4 3.8 3.5 10.2 2.3 2.5 3.0 2.4 2.9 3.1 3.6 2.5 33.6 9.6 2.8 2.3 2.5 40.0 3.3 4.2 6.8 4.3 6.6 11.3 16.3 4.3 5.5 5.5 0.0 13.3 4.5 0.8 27.4 6.4 14.8 15.1 491.6 17.2 1.8 5.7 0.5 5.1 11.2 439.9 7.1 11.0 1.3 0.7 33.9 44.8 20.8 16.8 2.5 0.9 6.1 1.9 53.6 27.6 140.5 5.5 32.0 9.4 0.8 12.1 6.2 1.5 0.2 4.1 1.3 50.4 2.1 2.2 0.1 2.5 6.8 2.0 32.9 14.2 442.2 32.8 21.0 3.6 33.1 25.2 9.4 22.6 0.7 3.0 PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.6;heart muscle: 123.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 138.0;Extravillous trophoblasts: 63.1;Fibroblasts: 225.8;Syncytiotrophoblasts: 241.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 65.5;RPMI-8226: 36.8;U-2197: 77.9;U-266/70: 68.6;U-266/84: 34.3" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 580000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.31e-1)" "unprognostic (3.75e-2)" "unprognostic (5.71e-6)" "unprognostic (8.36e-6)" "unprognostic (3.03e-2)" "unprognostic (1.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.39e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.74e-4)" "prognostic unfavorable (1.08e-4)" 87.6 2.8 0.8 4.0 0.9 14.9 29.1 0.4 1.0 21.5 0.8 6.9 0.1 4.2 2.2 7.8 3.9 1.5 123.2 1.3 1.9 17.9 18.3 16.4 2.3 0.7 1.1 3.9 1.4 0.7 23.7 48.1 0.6 21.5 5.1 0.7 3.1 8.9 2.4 5.3 2.8 8.7 0.5 3.0 3.4 2.4 1.5 0.7 6.4 22.1 1.9 25.7 26.0 0.8 1.4 11.0 3.4 0.0 65.5 18.1 0.0 1.0 0.2 2.9 3.6 0.7 1.2 0.0 3.3 4.9 14.8 0.1 13.7 0.0 3.4 0.0 21.0 2.5 6.8 0.0 0.0 1.5 0.0 6.9 0.0 6.9 1.7 14.5 0.2 2.2 0.5 0.0 1.4 2.0 4.5 1.2 5.5 0.2 21.9 0.0 8.1 36.8 3.2 0.1 7.6 4.6 17.8 0.0 6.5 4.7 0.0 4.5 0.0 5.8 12.8 77.9 6.0 68.6 34.3 0.0 16.6 1.9 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.4 1.0 1.3 1.9 0.7 1.1 0.6 0.5 1.5 0.8 17.3 0.0 3.2 0.7 0.2 7.4 0.7 0.9 0.6 18.0 0.5 0.6 37.3 0.0 0.9 12.9 25.0 138.0 0.2 0.2 0.0 0.0 0.6 2.1 2.2 4.5 0.0 0.0 1.6 0.0 63.1 225.8 0.5 3.7 1.3 29.0 0.4 11.8 15.3 6.7 2.2 0.2 0.0 0.6 12.4 1.0 0.6 6.7 3.6 1.9 0.0 13.8 0.0 29.7 1.6 0.5 0.4 0.0 0.0 2.1 0.0 0.0 0.0 12.6 0.0 6.1 16.9 25.8 47.7 1.0 7.4 241.6 1.1 19.1 0.0 0.4 PCSK1 "NEC1, PC1, PC3, SPC3" ENSG00000175426 "Proprotein convertase subtilisin/kexin type 1" P29120 5 96390333-96434143 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 68.3" "Cell type enriched" "Detected in some" 4 "Enteroendocrine cells: 224.6" "Cancer enhanced" "Detected in many" "breast cancer: 12.1" "Group enriched" "Detected in all" 5 "cerebral cortex: 19.1;hypothalamus: 68.3;pons: 30.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 22.6;U-138 MG: 19.0;U-87 MG: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048564, HPA079656" Approved "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA048564: AB_2680444, HPA079656: " "unprognostic (1.86e-2)" "unprognostic (2.13e-2)" "unprognostic (4.66e-3)" "unprognostic (8.20e-5)" "prognostic unfavorable (9.13e-5)" "unprognostic (8.47e-4)" "unprognostic (1.46e-1)" "unprognostic (5.84e-3)" "unprognostic (4.71e-1)" "unprognostic (3.07e-3)" "unprognostic (1.89e-3)" "unprognostic (1.01e-1)" "unprognostic (7.90e-6)" "unprognostic (5.25e-2)" "unprognostic (9.96e-2)" "unprognostic (1.33e-3)" "unprognostic (9.37e-3)" 1.7 6.3 5.5 4.7 3.7 0.1 1.4 1.0 19.1 0.9 0.0 2.4 5.2 0.1 0.0 0.1 0.2 0.2 0.8 3.0 68.3 0.4 0.0 0.3 0.1 6.6 7.7 0.4 7.6 0.0 12.1 0.0 30.0 0.4 2.3 8.7 2.7 0.1 0.3 1.1 3.6 0.6 4.0 0.1 5.7 0.1 6.6 0.2 1.9 0.0 0.0 2.0 0.5 5.3 0.0 0.0 0.3 0.0 2.3 0.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.1 1.0 3.8 0.0 0.0 0.1 0.0 0.1 0.1 0.8 2.4 0.0 0.0 0.0 0.0 2.0 1.0 0.4 0.1 0.2 0.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 3.3 0.0 0.0 0.4 0.0 0.0 1.2 19.0 0.6 0.3 0.2 0.0 0.0 0.1 15.8 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 3.7 1.0 19.1 3.0 68.3 6.6 7.7 30.0 4.0 6.6 5.3 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 1.8 13.2 0.0 0.0 0.7 0.0 0.0 0.0 2.1 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.2 0.2 224.6 0.0 54.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 4.0 10.7 2.0 0.0 0.4 1.6 0.0 0.0 0.0 4.7 0.0 0.5 0.0 3.5 4.9 1.5 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.9 0.0 1.7 1.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.7 0.0 PCSK1N "BigLEN, PEN, proSAAS, SAAS, SCG8, SgVIII" ENSG00000102109 "Proprotein convertase subtilisin/kexin type 1 inhibitor" Q9UHG2 X 48831096-48835610 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 642.6;pituitary gland: 1243.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 3045.7;Horizontal cells: 437.4;Paneth cells: 628.8;Proximal tubular cells: 1601.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 2.4;memory CD4 T-cell: 5.0;memory CD8 T-cell: 4.9;naive CD4 T-cell: 2.0;naive CD8 T-cell: 6.4;T-reg: 1.8" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cell line enhanced" "Detected in many" "HEK 293: 58.9;PC-3: 148.5;SCLC-21H: 58.2;SH-SY5Y: 53.8;SiHa: 52.1;U-266/84: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003925, HPA064734" Enhanced Supported Approved Vesicles "Secreted to blood" NA NA 3300000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA003925: AB_1079582, HPA064734: AB_2685339" "unprognostic (2.44e-3)" "unprognostic (5.86e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (3.36e-1)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (1.50e-3)" "unprognostic (2.79e-3)" "prognostic favorable (1.36e-4)" "unprognostic (3.34e-2)" "unprognostic (2.91e-2)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" 2.2 29.5 177.1 0.5 135.6 0.0 2.0 21.6 212.8 18.2 118.8 19.2 9.6 34.1 2.9 0.9 6.9 0.2 16.0 105.6 642.6 152.1 1.3 2.9 0.1 290.3 257.1 2.3 54.0 11.1 1243.7 0.2 193.0 14.4 0.5 2.5 6.7 0.8 0.8 8.8 13.7 0.6 95.5 1.1 21.9 19.7 264.9 0.0 3.3 0.0 0.0 1.2 6.5 51.8 0.1 5.4 0.2 14.9 0.6 0.0 0.4 0.0 0.0 0.0 0.0 5.3 0.1 0.0 10.4 0.0 4.2 0.8 0.0 1.1 0.0 0.0 58.9 0.0 0.0 9.3 0.0 0.0 3.7 0.0 0.8 0.0 0.0 2.2 0.0 0.0 0.0 0.2 0.0 7.6 0.0 0.5 7.9 0.0 148.5 0.0 0.0 0.4 1.4 0.2 58.2 53.8 52.1 0.2 4.9 0.7 0.2 0.1 0.1 0.1 22.7 0.2 5.0 13.3 73.6 0.3 0.4 0.0 1.5 0.0 0.0 0.0 0.8 0.0 2.4 0.0 5.0 4.9 0.0 0.0 2.0 6.4 0.0 0.0 0.0 0.0 1.8 0.7 177.1 135.6 21.6 212.8 105.6 642.6 290.3 257.1 193.0 95.5 264.9 51.8 0.8 0.0 0.0 29.0 12.5 15.8 1.3 4.3 0.6 139.6 11.4 14.9 1.4 2.8 4.3 389.9 52.1 1.0 1.0 18.2 277.8 8.6 12.8 44.3 8.7 3.6 3045.7 2.7 64.8 0.7 69.0 17.2 112.1 35.2 0.0 2.5 0.0 0.5 1.7 437.4 118.8 218.9 54.9 0.3 17.2 52.9 3.4 10.5 56.9 22.5 0.4 96.2 1.0 72.9 26.0 23.1 628.8 7.2 4.5 30.4 21.6 1601.1 24.8 148.2 0.0 0.3 12.6 32.5 82.2 0.2 11.5 1.9 20.1 0.2 15.6 3.7 PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 28.5;brain: 30.2;retina: 35.8;thyroid gland: 56.9" "Cell type enhanced" "Detected in many" "Early spermatids: 87.3;Excitatory neurons: 322.8;Horizontal cells: 132.9;Inhibitory neurons: 148.8;Melanocytes: 209.9;Muller glia cells: 452.7" "Cancer enriched" "Detected in many" 4 "thyroid cancer: 65.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 60.0;SCLC-21H: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" NA NA 18000 "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA049627: AB_2680835" "unprognostic (2.03e-3)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.07e-3)" "unprognostic (4.31e-1)" "unprognostic (5.88e-2)" "unprognostic (2.50e-3)" "unprognostic (2.14e-1)" "unprognostic (7.26e-5)" "unprognostic (2.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" 0.7 28.5 8.6 0.8 14.9 0.5 0.4 0.1 30.2 1.6 0.0 6.9 4.8 0.2 0.3 1.1 1.0 0.5 4.7 15.8 11.1 0.2 0.2 2.5 0.0 2.2 1.3 9.0 19.8 0.8 2.0 0.6 2.6 1.4 1.7 35.8 1.7 1.2 0.1 14.1 2.1 0.4 1.4 0.1 8.1 4.8 13.2 0.0 56.9 0.1 0.1 3.0 2.4 11.9 0.0 0.0 60.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 14.9 0.1 30.2 15.8 11.1 2.2 1.3 2.6 1.4 13.2 11.9 0.1 0.0 7.3 7.8 0.0 8.2 0.0 0.0 1.2 28.1 0.0 0.0 1.2 0.0 0.6 0.0 6.2 0.0 0.0 0.0 0.0 0.0 87.3 0.0 0.0 1.3 0.0 0.0 322.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 132.9 148.8 0.6 0.0 0.0 1.3 6.3 2.8 0.2 209.9 8.4 0.0 452.7 0.0 44.7 6.4 2.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.5 1.2 1.0 0.3 0.2 1.4 0.0 0.1 0.6 0.0 0.1 PCSK4 "DKFZp434B217, MGC34749, PC4, SPC5" ENSG00000115257 "Proprotein convertase subtilisin/kexin type 4" Q6UW60 19 1481428-1490752 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 66.0" "Group enriched" "Detected in many" 4 "Early spermatids: 277.1;Late spermatids: 679.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.7;HMC-1: 3.7;JURKAT: 5.3;U-266/70: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA005572 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA005572: AB_1855087" "unprognostic (1.00e-2)" "unprognostic (9.12e-2)" "unprognostic (2.36e-3)" "prognostic favorable (9.45e-5)" "unprognostic (5.23e-2)" "unprognostic (6.14e-2)" "unprognostic (1.78e-1)" "unprognostic (6.34e-3)" "unprognostic (2.94e-1)" "unprognostic (8.29e-3)" "unprognostic (1.93e-2)" "unprognostic (7.44e-2)" "unprognostic (6.56e-2)" "unprognostic (3.82e-2)" "unprognostic (1.71e-2)" "unprognostic (3.57e-2)" "unprognostic (7.03e-2)" 0.8 1.4 1.1 0.3 1.1 0.6 1.2 0.9 2.5 1.7 1.3 1.3 1.7 1.1 0.1 1.1 3.2 0.6 0.5 1.4 1.6 3.7 4.0 1.1 0.3 1.9 2.8 1.1 2.8 0.9 7.1 0.2 1.5 1.8 0.1 0.6 1.1 1.2 0.3 0.6 1.1 0.1 1.8 0.7 1.4 66.0 1.6 0.4 3.4 0.0 0.1 1.0 1.2 0.9 0.6 0.3 1.2 6.7 0.1 0.2 1.8 0.5 0.1 0.0 0.2 0.6 1.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.1 0.3 1.1 1.0 0.4 0.0 3.7 0.6 0.0 0.0 0.1 0.3 0.2 5.3 1.2 1.8 0.0 0.0 0.1 0.3 0.1 0.3 0.4 1.2 0.1 0.1 0.4 0.0 0.0 1.4 0.1 0.3 0.1 0.4 2.5 0.4 0.0 0.5 0.0 0.1 0.0 7.7 1.5 0.3 0.3 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 1.1 0.9 2.5 1.4 1.6 1.9 2.8 1.5 1.8 1.6 0.9 0.2 0.0 1.1 12.1 0.1 0.6 0.9 1.8 0.6 1.5 3.1 2.2 2.3 1.5 3.6 0.0 8.4 0.5 1.7 1.6 5.9 1.8 277.1 5.2 1.0 0.5 0.0 1.7 3.2 1.0 0.5 0.8 3.1 1.1 0.0 3.3 0.0 3.2 0.8 3.3 3.7 1.4 0.0 0.3 0.0 679.2 6.2 1.1 3.6 3.7 0.0 2.4 0.0 1.0 1.6 0.9 1.1 5.3 1.4 0.5 2.8 1.9 8.3 9.1 0.0 0.2 0.5 98.0 9.6 1.2 0.0 0.3 0.7 2.4 2.1 0.7 PCSK5 "PC5, PC6, SPC6" ENSG00000099139 "Proprotein convertase subtilisin/kexin type 5" Q92824 9 75890644-76362975 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Pregnancy "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 189.7;Inhibitory neurons: 81.9;NK-cells: 82.4;Oligodendrocyte precursor cells: 149.3;Proximal enterocytes: 99.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 2447.1;neutrophil: 626.3" "Lineage enriched" "Detected in all" 18 "granulocytes: 2447.1" "Cell line enhanced" "Detected in many" "BEWO: 32.6;HaCaT: 46.9;RH-30: 30.4;RPTEC TERT1: 42.5;U-2 OS: 66.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031072 Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 290000 "Cluster 41: Basophils - Cellular respiration" "Cluster 45: Intestine - Brush border" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA031072: AB_10602190" "unprognostic (3.28e-2)" "unprognostic (1.44e-1)" "unprognostic (4.13e-4)" "unprognostic (4.08e-2)" "unprognostic (7.43e-3)" "unprognostic (3.17e-1)" "unprognostic (2.07e-3)" "unprognostic (9.39e-2)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (2.81e-2)" "unprognostic (6.80e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (2.99e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-2)" "unprognostic (1.77e-5)" 17.6 4.2 6.6 5.9 6.6 2.3 6.9 22.2 23.8 9.0 0.0 10.2 25.0 7.1 9.6 8.5 6.9 8.6 5.3 7.4 7.8 3.8 1.7 6.1 2.7 21.7 17.3 13.5 3.0 5.9 2.3 9.4 20.0 3.3 8.4 6.0 3.5 3.0 3.0 3.6 26.4 6.6 23.0 3.3 3.3 6.3 5.3 9.1 4.8 5.4 2.5 5.3 8.8 2.4 2.5 1.8 5.1 3.4 3.2 1.0 32.6 4.7 0.4 0.3 0.0 18.7 2.0 0.8 1.3 0.6 0.1 46.9 2.4 1.4 0.3 0.6 4.1 6.3 4.5 1.6 0.8 1.9 2.8 6.0 0.4 1.0 0.5 0.3 9.6 3.1 7.5 2.4 3.3 11.5 7.4 11.1 22.8 4.3 1.9 1.3 30.4 1.9 42.5 2.9 0.7 0.5 7.1 1.5 0.5 9.5 2.6 8.0 7.6 1.5 66.5 3.8 2.0 0.7 0.3 1.0 5.1 2.7 25.7 2447.1 43.1 192.4 100.0 25.9 85.2 92.3 100.8 93.7 21.8 116.5 98.2 125.2 626.3 135.5 51.6 135.0 96.9 10.1 6.6 6.6 22.2 23.8 7.4 7.8 21.7 17.3 20.0 23.0 5.3 2.4 41.1 6.4 7.2 189.7 0.1 6.5 3.5 8.6 13.6 4.8 0.7 2.0 5.8 11.5 14.3 5.5 0.0 2.1 9.6 47.3 0.0 8.2 19.0 6.0 35.1 19.5 1.2 0.0 33.5 6.1 34.3 26.6 9.7 10.6 0.0 32.1 15.0 0.9 2.9 55.5 81.9 10.2 6.1 4.1 3.9 39.4 20.5 7.5 1.8 70.3 11.4 30.3 82.4 149.3 5.8 10.1 18.5 25.2 0.4 2.9 99.2 4.2 23.4 1.4 19.7 9.1 11.4 1.0 1.9 6.2 3.0 2.5 6.2 5.6 23.9 0.9 PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101289784-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 153.6;liver: 160.0;lymphoid tissue: 81.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 231.6;Horizontal cells: 196.9;Oligodendrocytes: 561.9;Theca cells: 106.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 47.2;CACO-2: 35.7;HEK 293: 60.3;Hep G2: 53.8;OE19: 65.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" NA NA 480000 "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA004774: AB_1079583" "prognostic favorable (9.99e-4)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (2.46e-2)" "unprognostic (9.83e-2)" "unprognostic (8.14e-2)" "unprognostic (2.20e-3)" "unprognostic (8.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.39e-2)" "unprognostic (3.85e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.06e-7)" "unprognostic (2.02e-1)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" 5.3 2.2 17.5 3.0 67.3 1.1 11.2 57.8 37.0 2.2 4.2 16.5 6.8 2.0 3.3 9.0 2.8 3.1 20.0 19.3 34.1 3.2 160.0 3.6 2.5 113.0 64.5 6.1 2.6 0.6 5.1 32.0 95.6 3.1 14.8 7.6 2.8 0.6 11.4 10.1 10.1 3.6 42.9 81.4 9.8 13.0 54.0 20.9 2.2 16.3 1.8 3.7 2.6 153.6 19.7 14.6 2.6 0.9 0.2 0.4 47.2 0.7 2.5 0.0 0.1 35.7 8.3 0.4 2.4 0.6 1.1 11.4 12.5 1.5 0.0 2.8 60.3 33.5 8.4 53.8 1.6 4.5 0.4 0.3 7.5 0.2 0.2 0.2 0.1 4.3 24.5 0.2 0.0 8.8 0.1 4.7 9.3 65.9 6.5 0.2 0.4 4.4 4.4 25.4 7.3 8.6 26.2 1.5 9.1 6.6 2.2 21.9 0.2 0.3 1.2 0.3 0.2 0.5 0.6 0.7 0.2 0.6 7.3 0.8 0.2 0.9 0.2 0.4 0.3 0.5 0.4 0.2 0.1 1.0 0.6 0.5 0.4 3.3 1.3 0.4 0.1 1.2 17.5 67.3 57.8 37.0 19.3 34.1 113.0 64.5 95.6 42.9 54.0 153.6 1.7 3.2 0.6 2.9 1.3 0.4 0.3 0.9 0.6 1.7 15.4 6.6 2.0 8.6 1.4 1.8 20.9 6.7 0.6 22.6 0.0 0.6 1.6 4.7 21.6 4.9 0.0 3.2 19.4 0.8 24.3 15.5 1.5 6.9 0.0 4.2 12.5 231.6 1.4 196.9 30.8 3.7 0.0 5.2 1.1 2.4 10.5 1.7 0.0 5.6 1.0 1.7 3.1 25.6 561.9 7.3 8.2 0.0 0.0 1.7 2.3 0.1 1.2 1.6 0.0 2.0 1.0 4.7 2.4 0.9 0.1 3.3 1.0 106.5 8.5 0.2 PCSK9 "FH3, HCHOLA3, NARC-1" ENSG00000169174 "Proprotein convertase subtilisin/kexin type 9" Q8NBP7 1 55039447-55064852 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 48.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Alveolar cells type 2: 22.4;Gastric mucus-secreting cells: 8.2;Hepatocytes: 32.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 3.4;medulla oblongata: 2.1;pons: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 82.5;CACO-2: 37.0;HaCaT: 108.8;HeLa: 90.7;RPTEC TERT1: 56.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 143000000 420000000 "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.28e-3)" "unprognostic (6.93e-2)" "unprognostic (4.02e-1)" "unprognostic (2.19e-2)" "unprognostic (7.30e-2)" "unprognostic (1.82e-1)" "unprognostic (1.20e-3)" "unprognostic (1.14e-2)" "unprognostic (5.44e-3)" "unprognostic (1.22e-2)" "unprognostic (2.09e-3)" "unprognostic (3.70e-2)" "unprognostic (2.45e-4)" "unprognostic (1.49e-1)" "unprognostic (1.86e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (2.40e-4)" 0.3 0.2 0.0 0.7 0.1 0.4 0.1 3.4 0.3 1.0 0.0 4.5 3.1 0.3 0.3 5.5 0.4 0.1 0.0 0.1 0.1 0.1 48.7 7.9 0.0 2.1 0.3 0.1 5.4 0.2 0.1 0.0 2.0 0.0 1.6 0.0 0.5 0.2 0.0 1.4 3.4 0.7 0.0 0.3 1.3 0.4 0.1 0.0 0.0 0.0 0.3 0.4 1.5 0.2 82.5 17.6 2.8 0.0 6.4 4.4 0.2 0.0 0.0 0.2 0.2 37.0 13.2 0.0 13.9 7.8 0.3 108.8 3.5 35.2 0.0 0.0 0.0 0.0 90.7 26.5 2.2 0.0 0.0 6.4 25.5 25.2 18.4 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 15.1 1.5 1.9 0.0 0.0 0.9 56.4 0.1 1.3 0.0 10.5 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.3 0.1 0.1 2.1 0.3 2.0 0.0 0.1 0.2 0.0 16.0 22.4 0.0 0.2 0.5 0.0 2.1 1.2 0.0 0.0 0.0 0.6 0.0 1.8 0.0 0.0 0.0 0.0 2.0 0.0 0.5 0.2 0.8 0.1 0.1 4.2 2.7 0.1 1.5 0.0 0.6 8.2 0.8 0.0 0.1 1.1 32.9 0.1 0.0 0.1 4.3 2.0 1.6 0.5 0.6 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.1 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.6 1.3 1.4 0.6 0.0 0.1 0.0 5.4 0.4 PCYOX1 "KIAA0908, PCL1" ENSG00000116005 "Prenylcysteine oxidase 1" Q9UHG3 2 70257386-70281185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 599.4;Hepatocytes: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 313.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035193 Approved "Intracellular and membrane" NA NA 510000000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA035193: AB_10602017" "unprognostic (1.09e-1)" "unprognostic (1.72e-2)" "unprognostic (7.91e-2)" "unprognostic (1.15e-2)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (6.87e-2)" "unprognostic (6.28e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (1.61e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.26e-2)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" 78.5 33.5 15.4 12.7 15.7 3.7 34.4 12.1 18.4 56.5 29.3 26.9 24.9 39.9 33.6 38.8 35.6 31.7 37.7 14.7 27.8 92.6 103.5 56.2 14.6 16.5 22.0 39.6 20.6 66.0 17.9 29.0 24.9 44.3 23.6 30.7 70.1 46.6 92.1 33.0 24.5 40.8 14.6 15.6 22.1 14.2 28.4 11.1 60.0 50.4 14.2 25.7 25.2 13.2 38.8 54.9 43.2 48.6 313.2 160.0 37.9 64.8 59.4 35.4 26.5 86.5 33.6 4.0 27.3 89.2 58.2 62.2 31.7 50.2 40.5 22.1 26.9 14.9 41.0 75.7 31.4 14.1 12.7 154.9 54.1 47.4 13.3 93.9 42.6 14.2 27.0 27.8 50.7 23.6 10.7 22.8 26.1 55.9 23.1 19.6 90.2 34.5 50.1 42.8 11.3 24.1 97.8 47.7 45.5 61.0 39.1 18.2 53.4 59.2 32.7 52.9 34.2 22.9 55.1 5.1 71.3 19.3 22.1 16.3 6.5 6.8 8.3 5.4 10.4 3.7 8.0 6.7 5.9 2.8 10.8 9.2 4.1 6.1 6.0 7.4 7.8 6.5 15.4 15.7 12.1 18.4 14.7 27.8 16.5 22.0 24.9 14.6 28.4 13.2 37.3 599.4 77.5 16.0 12.2 21.3 23.1 43.9 29.6 48.7 46.0 31.8 81.1 40.0 49.9 53.3 43.8 43.4 12.1 30.7 7.9 26.7 1.7 18.4 65.9 33.4 8.5 12.0 24.7 10.2 36.0 81.9 22.4 36.2 10.1 20.9 39.7 187.8 22.1 57.2 36.8 21.0 36.7 17.4 9.2 3.9 89.2 14.3 24.9 23.4 8.6 90.3 11.3 21.6 18.0 13.9 21.0 120.7 26.2 27.0 47.7 69.0 25.0 36.9 72.3 65.5 63.7 14.7 32.2 40.8 28.3 22.0 14.5 56.2 26.5 18.4 PCYOX1L MGC3265 ENSG00000145882 "Prenylcysteine oxidase 1 like" Q8NBM8 5 149358037-149369653 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 17.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 50.2;RPMI-8226: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037463, HPA038402" Approved Approved Nucleoplasm,Mitochondria "Secreted to blood" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Mitochondria" "HPA037463: AB_10673632, HPA038402: AB_2675997" "unprognostic (1.34e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (1.22e-1)" "unprognostic (7.83e-2)" "unprognostic (5.73e-2)" "unprognostic (4.18e-3)" "unprognostic (7.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.25e-1)" "unprognostic (3.05e-3)" "unprognostic (8.77e-2)" "unprognostic (4.90e-2)" "unprognostic (2.86e-1)" "unprognostic (2.49e-1)" "unprognostic (2.26e-3)" "unprognostic (3.28e-1)" 3.2 4.6 2.3 5.3 2.4 3.9 3.3 2.4 4.5 5.1 0.2 3.2 1.8 4.9 0.6 3.5 5.3 4.7 3.9 2.9 4.4 2.0 0.5 3.4 6.6 3.7 2.5 5.7 3.1 17.5 4.9 4.2 5.0 3.9 0.7 7.6 2.9 4.5 0.8 5.4 4.8 5.2 1.0 4.0 3.7 6.4 2.3 4.6 2.7 1.8 3.2 3.8 3.8 2.3 4.3 2.7 9.2 20.3 7.8 7.9 4.9 9.0 4.0 7.8 13.2 0.8 7.6 17.9 27.1 6.7 36.1 7.7 8.8 20.3 0.7 8.4 8.2 8.4 0.0 0.7 17.3 7.3 9.1 14.9 3.0 10.7 12.6 9.4 17.3 16.6 4.9 50.2 0.4 17.9 8.1 11.2 4.7 15.8 16.3 10.7 6.7 50.8 4.9 2.0 13.3 13.6 17.9 11.9 14.6 10.0 20.0 12.4 8.2 6.8 5.5 14.7 4.2 20.1 29.2 10.6 11.2 38.3 14.6 3.0 7.1 4.0 2.8 9.6 3.7 1.6 5.3 2.1 13.2 1.0 6.3 4.4 1.2 4.8 9.6 0.9 7.3 4.7 2.3 2.4 2.4 4.5 2.9 4.4 3.7 2.5 5.0 1.0 2.3 2.3 4.5 9.6 1.7 2.9 2.3 1.0 1.0 3.2 2.8 5.2 2.4 1.8 5.3 4.3 3.6 1.8 0.0 6.0 1.9 0.6 0.0 3.0 3.3 3.2 2.4 4.6 0.0 2.5 10.5 2.3 6.6 5.0 2.0 2.3 2.5 9.6 2.5 0.4 7.6 11.8 12.4 1.8 6.1 8.2 1.4 1.5 3.4 6.9 1.8 4.7 7.0 7.8 1.0 5.5 4.9 2.1 1.7 2.6 1.3 0.8 2.6 0.6 2.8 14.2 0.0 2.5 2.7 1.2 3.5 1.9 1.6 1.2 5.6 9.7 2.3 0.9 PDE10A ENSG00000112541 "Phosphodiesterase 10A" Q9Y233 6 165327287-165988078 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 67.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 204.7;Inhibitory neurons: 209.6;Microglial cells: 89.0;Oligodendrocyte precursor cells: 48.7;Oligodendrocytes: 51.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "basal ganglia: 67.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 9.0;LHCN-M2: 12.5;RT4: 6.9;SH-SY5Y: 8.1;TIME: 11.3;U-2 OS: 7.0" "Region enriched" "Detected in all" 11 "basal ganglia: 350.1" "Region enriched" "Detected in all" 5 "basal ganglia: 194.1" "CAB045998, HPA047200" Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB045998: AB_2162589, HPA047200: AB_2679981" "unprognostic (1.02e-1)" "unprognostic (3.63e-2)" "unprognostic (3.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.20e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (9.36e-2)" "unprognostic (6.03e-2)" "unprognostic (3.79e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (4.44e-7)" "unprognostic (3.59e-3)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (5.90e-3)" 2.6 1.3 3.1 0.8 67.2 0.0 2.3 5.5 10.7 1.3 0.0 1.0 0.2 2.0 2.4 0.4 2.4 1.5 3.6 2.1 2.5 3.8 0.3 1.0 0.5 1.6 2.3 2.3 0.5 0.5 2.7 2.5 0.9 1.7 0.2 1.9 0.4 1.7 0.4 0.3 0.7 2.1 0.5 1.4 1.1 3.4 9.6 0.3 6.0 0.5 0.4 3.2 0.9 0.1 0.0 2.4 5.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.3 0.8 0.0 0.0 0.0 3.8 0.1 2.2 0.0 0.0 0.1 3.9 0.0 9.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.5 0.0 0.0 0.0 12.5 0.3 0.9 0.0 1.1 0.0 4.7 1.5 5.8 0.0 5.9 6.9 1.8 8.1 0.0 0.0 0.4 0.7 0.0 0.0 11.3 0.1 7.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 67.2 5.5 10.7 2.1 2.5 1.6 2.3 0.9 0.5 9.6 0.1 13.8 0.0 0.0 10.4 0.1 0.4 3.3 0.4 0.0 7.2 0.3 0.3 7.3 0.0 1.2 5.5 2.1 7.8 0.0 0.0 3.9 2.0 14.3 0.2 1.7 13.4 0.0 0.0 204.7 0.0 6.1 6.6 1.1 0.4 1.3 0.1 7.9 0.0 0.8 16.8 209.6 0.0 0.0 0.0 0.0 14.9 0.0 0.2 1.8 89.0 0.0 12.6 0.0 48.7 51.8 0.1 0.0 0.4 0.0 17.9 0.0 7.2 0.9 1.1 0.0 12.4 5.0 8.8 2.1 0.1 0.3 2.9 0.1 1.6 0.1 6.9 PDE11A ENSG00000128655 "Phosphodiesterase 11A" Q9HCR9 2 177623244-178072777 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Cushing syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 6.3;parathyroid gland: 9.8" "Cell type enhanced" "Detected in many" "Early spermatids: 37.0;Hepatocytes: 11.1;Late spermatids: 46.4;Oligodendrocytes: 14.9" "Cancer enhanced" "Detected in some" "prostate cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.6;fHDF/TERT166: 2.4;HAP1: 1.4;Hep G2: 2.8" HPA034560 Approved "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA034560: AB_10602140" "unprognostic (1.02e-1)" "unprognostic (4.73e-2)" "unprognostic (1.02e-1)" "unprognostic (9.61e-3)" "unprognostic (2.34e-2)" "unprognostic (1.43e-2)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "unprognostic (3.91e-1)" "unprognostic (9.95e-2)" "unprognostic (2.80e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-4)" "unprognostic (1.64e-3)" 2.3 0.3 0.8 0.1 2.0 0.2 1.7 1.9 1.2 0.6 0.6 0.5 0.8 1.2 0.4 0.0 0.3 0.4 0.3 0.6 2.1 0.5 6.3 0.0 0.0 2.5 2.1 0.4 1.1 9.8 0.9 0.0 2.7 5.2 0.4 1.4 1.4 0.8 4.4 0.1 0.5 1.1 3.7 0.1 0.4 2.8 1.9 0.1 1.3 1.3 0.0 0.0 0.1 3.2 0.0 0.4 0.2 0.1 0.0 0.0 0.0 1.1 0.2 0.0 0.3 0.2 1.6 0.0 0.6 2.4 0.3 0.1 1.4 0.0 0.0 0.0 0.9 1.1 0.1 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.2 0.2 0.4 0.1 0.6 0.0 0.3 0.2 0.0 0.2 0.0 0.5 0.0 0.3 0.7 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.8 2.0 1.9 1.2 0.6 2.1 2.5 2.1 2.7 3.7 1.9 3.2 0.1 0.0 0.0 2.3 0.2 0.6 1.4 0.1 0.0 1.7 4.2 0.8 0.0 1.5 0.1 0.0 0.0 0.1 0.3 0.8 0.0 0.8 37.0 0.3 0.2 0.6 6.7 2.7 1.6 6.7 0.0 0.6 0.0 0.2 0.0 0.0 1.4 11.1 0.1 0.0 8.2 0.9 6.1 1.2 2.1 46.4 1.5 0.3 0.0 0.0 0.0 4.7 0.0 6.0 14.9 2.3 0.0 0.7 0.0 5.4 0.6 1.3 0.1 1.0 0.0 2.0 0.6 6.8 6.9 0.0 1.3 0.3 0.3 0.3 1.3 1.0 PDF ENSG00000258429 "Peptide deformylase, mitochondrial" Q9HBH1 16 69326913-69330588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 27.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 8.0;Erythroid cells: 4.6;Gastric mucus-secreting cells: 8.6;Plasma cells: 14.7;Squamous epithelial cells: 17.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063409 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" No No "Cluster 24: B-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA063409: AB_2685007" "unprognostic (4.28e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.98e-3)" "prognostic unfavorable (7.35e-4)" "unprognostic (5.84e-2)" "unprognostic (4.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.00e-1)" "prognostic favorable (6.11e-4)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (5.98e-2)" "unprognostic (1.22e-2)" 5.9 8.7 1.0 0.9 1.3 1.4 5.5 1.9 1.8 4.4 1.5 5.6 2.1 5.8 0.4 10.2 4.7 0.5 5.3 2.2 0.8 19.0 27.8 4.4 1.1 1.4 0.8 3.1 8.8 1.6 4.3 0.6 1.0 5.0 0.8 0.3 7.2 0.6 12.4 7.7 5.2 0.4 0.8 5.1 5.6 4.8 0.9 0.6 5.9 0.8 0.7 4.8 4.8 1.5 6.3 4.8 1.3 4.1 1.1 0.8 7.7 6.0 1.0 2.9 2.4 8.6 5.7 13.1 6.2 1.6 2.2 11.5 1.8 2.1 1.3 3.5 23.3 6.6 5.3 12.6 1.8 10.8 5.7 1.7 4.3 2.5 1.2 0.8 1.5 7.2 16.1 2.4 1.9 7.6 9.2 8.3 6.4 2.6 7.1 20.8 2.1 11.0 2.2 5.4 9.3 7.1 10.8 2.9 5.2 0.3 11.0 3.3 4.6 3.9 6.4 5.8 6.8 12.1 9.4 15.2 3.1 6.9 5.9 1.4 0.7 1.0 0.4 0.3 0.9 1.2 1.0 1.2 0.6 4.1 1.5 0.7 0.0 0.4 0.4 1.3 0.9 0.3 1.0 1.3 1.9 1.8 2.2 0.8 1.4 0.8 1.0 0.8 0.9 1.5 0.2 3.2 0.0 0.0 3.0 0.0 0.1 0.0 8.0 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.5 0.3 0.6 0.0 4.6 0.0 0.2 0.3 1.2 8.6 0.5 0.0 0.2 0.4 0.8 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 14.7 0.1 0.4 1.1 0.0 0.0 0.0 0.1 0.8 0.2 0.1 17.7 0.4 0.3 1.4 0.1 0.0 0.1 PDGFA "PDGF-A, PDGF1" ENSG00000197461 "Platelet derived growth factor subunit A" P04085 7 497258-520296 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 95.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 89.8;Breast myoepithelial cells: 154.9;Paneth cells: 97.0;Smooth muscle cells: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 11.3" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 4 "WM-115: 311.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005579, HPA065024" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 580000 "Cluster 42: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "CAB005579: AB_2161916, HPA065024: " "unprognostic (2.22e-1)" "unprognostic (2.83e-1)" "unprognostic (1.17e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.75e-4)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.63e-3)" "unprognostic (4.37e-2)" "unprognostic (3.02e-1)" "unprognostic (1.96e-1)" "unprognostic (1.85e-1)" "unprognostic (8.26e-2)" "unprognostic (1.07e-2)" "unprognostic (5.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (8.67e-4)" 15.4 8.5 29.3 7.9 36.8 1.7 17.0 36.6 32.4 18.1 20.5 29.2 20.2 26.1 11.2 9.6 21.2 11.4 21.1 27.0 27.5 22.2 8.5 24.9 3.5 46.4 37.5 7.7 71.6 6.6 10.2 26.8 40.7 23.3 14.8 5.2 20.3 11.2 95.2 12.5 25.9 10.2 35.8 16.3 32.1 4.5 36.5 6.6 10.0 15.1 2.4 17.8 15.9 58.8 22.9 15.3 1.5 21.6 4.1 0.7 50.7 5.0 2.9 6.4 4.4 23.8 25.3 0.6 8.7 4.3 2.9 56.6 1.5 69.0 3.4 12.9 2.3 0.3 13.3 8.7 26.9 2.4 2.2 3.0 26.8 3.3 21.3 8.5 12.5 1.3 2.3 3.1 15.8 28.7 3.5 5.0 40.1 8.9 3.3 11.6 1.5 2.5 9.0 5.3 2.1 1.8 76.5 4.2 13.3 47.5 10.7 2.6 37.3 13.6 37.8 8.0 31.0 0.9 1.4 0.8 12.3 7.1 311.4 11.3 1.6 2.4 1.6 1.9 2.2 1.9 1.6 1.5 1.5 1.8 1.9 2.0 4.9 3.4 3.3 2.1 1.8 2.1 29.3 36.8 36.6 32.4 27.0 27.5 46.4 37.5 40.7 35.8 36.5 58.8 15.2 89.8 11.9 11.1 1.5 28.0 20.2 12.1 59.7 15.7 12.7 154.9 29.9 15.7 11.0 14.7 8.4 8.8 1.7 76.9 5.9 15.8 0.3 49.0 4.2 19.4 13.1 0.0 7.7 53.3 5.4 12.3 41.8 35.7 10.8 18.1 21.0 1.0 2.0 32.0 5.9 40.5 2.0 1.3 10.4 0.1 2.1 14.8 14.2 6.5 1.5 0.7 1.0 5.0 27.5 72.6 97.0 6.4 4.4 29.4 47.2 8.5 4.5 2.1 39.5 48.9 110.3 0.5 1.8 9.4 9.8 2.9 3.9 0.2 32.1 18.2 PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Endothelial cells: 60.6;Langerhans cells: 44.3;Macrophages: 25.5;Pancreatic endocrine cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Cell line enhanced" "Detected in many" "A-431: 33.8;EFO-21: 69.2;HUVEC TERT2: 52.6;SK-BR-3: 53.5;TIME: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" 32.6 6.4 14.7 7.1 10.7 0.4 24.0 10.3 22.2 7.5 4.8 20.6 4.9 8.9 5.2 6.2 7.2 11.7 31.2 12.0 9.8 17.0 3.7 28.1 7.4 13.6 12.4 3.8 8.8 8.9 4.0 40.2 12.0 7.6 3.5 0.8 10.6 5.2 18.7 10.3 9.1 9.2 10.6 6.6 7.9 3.4 16.0 2.1 16.1 11.0 1.6 8.5 6.6 9.4 33.8 2.6 8.4 0.0 0.0 0.0 9.9 0.1 0.4 0.2 0.0 13.0 10.3 0.0 69.2 0.0 3.1 12.4 0.5 2.8 0.0 0.1 0.2 0.7 1.1 4.8 4.3 0.0 18.1 0.0 0.3 0.0 0.4 0.9 52.6 0.0 1.3 6.1 1.9 13.7 0.1 0.1 3.2 8.1 3.4 0.0 0.3 22.8 27.7 0.1 0.2 0.0 0.6 53.5 0.2 6.0 24.3 0.1 68.1 0.1 6.4 0.1 7.5 0.1 0.4 0.3 0.1 1.5 31.3 0.0 0.0 0.0 7.3 0.1 10.0 0.0 4.3 5.6 0.0 0.0 3.6 1.9 0.1 0.0 0.4 1.3 2.3 2.1 14.7 10.7 10.3 22.2 12.0 9.8 13.6 12.4 12.0 10.6 16.0 9.4 75.0 0.0 1.1 0.0 0.6 2.8 1.2 3.8 1.2 0.7 5.1 7.1 3.1 0.0 1.3 7.3 0.0 7.3 4.0 0.1 0.0 20.0 1.3 4.0 0.7 60.6 1.8 0.0 2.8 3.6 6.5 1.6 0.0 5.6 0.0 13.1 16.8 1.4 7.7 0.0 0.9 0.7 4.1 2.6 44.3 0.1 0.6 25.5 1.8 14.0 1.1 0.3 0.0 0.0 0.2 54.7 0.0 0.0 0.0 2.7 0.1 1.9 0.9 0.1 6.6 4.7 9.6 0.3 1.6 1.1 1.4 4.5 2.0 1.2 0.1 0.6 PDGFC "fallotein, SCDGF" ENSG00000145431 "Platelet derived growth factor C" Q9NRA1 4 156760454-156971799 "Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 98.6;Granulosa cells: 124.1;Microglial cells: 85.3;Oligodendrocyte precursor cells: 233.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 60.0;hTERT-RPE1: 56.8;U-138 MG: 41.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009134 Approved Supported "Plasma membrane,Cytosol" "Secreted to blood" NA NA 37000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "HPA009134: AB_10601981" "unprognostic (3.12e-1)" "unprognostic (1.91e-2)" "unprognostic (5.79e-2)" "unprognostic (3.67e-2)" "unprognostic (3.97e-1)" "unprognostic (3.41e-2)" "unprognostic (8.78e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (8.12e-2)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" "prognostic favorable (1.35e-5)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.25e-1)" "unprognostic (1.19e-2)" "prognostic unfavorable (3.17e-4)" 4.8 4.0 0.9 1.3 1.0 0.6 7.5 0.4 1.0 9.2 0.7 2.3 2.0 9.9 2.1 3.3 6.7 4.8 2.6 1.0 0.8 5.5 5.1 3.1 1.1 0.8 0.7 7.7 4.3 20.3 0.4 4.5 0.7 8.7 2.0 0.7 8.4 7.0 1.2 1.6 2.8 9.4 0.9 1.3 2.8 0.9 1.1 2.0 6.5 1.2 1.0 3.2 1.2 1.0 2.5 3.7 38.6 25.4 7.0 13.4 1.0 21.5 21.5 12.0 16.1 2.2 9.4 0.0 3.8 60.0 9.2 2.6 10.8 13.4 16.5 0.0 5.0 25.5 3.2 2.4 18.3 3.9 0.3 14.2 6.6 30.6 21.7 56.8 6.0 0.1 0.1 0.1 30.2 0.1 0.0 0.0 0.4 0.0 1.7 0.0 8.1 0.0 22.5 0.9 0.0 0.0 0.0 0.2 0.4 6.0 3.1 1.3 28.3 41.7 0.4 10.9 17.3 0.0 0.0 0.0 16.1 0.0 1.6 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.9 1.0 0.4 1.0 1.0 0.8 0.8 0.7 0.7 0.9 1.1 1.0 2.4 6.4 14.2 98.6 0.7 49.6 22.7 12.4 25.0 2.0 14.7 13.6 16.8 58.6 7.8 12.9 0.0 0.6 3.4 0.5 0.0 15.4 30.5 6.9 15.0 7.3 0.0 5.5 64.4 7.1 0.3 18.6 8.2 11.4 1.3 124.1 10.0 15.9 13.0 0.0 32.1 2.1 4.1 34.4 21.6 23.8 5.3 32.1 10.6 85.3 14.2 6.3 0.0 233.2 3.0 18.0 0.5 23.0 1.4 8.7 2.4 18.6 3.5 0.5 6.6 34.8 18.2 0.7 2.9 3.4 13.5 0.5 0.9 13.8 2.1 4.8 PDGFD "IEGF, MSTP036, SCDGF-B" ENSG00000170962 "Platelet derived growth factor D" Q9GZP0 11 103907189-104164379 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 106.5;ovary: 78.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;dendritic cells: 30.0;Ductal cells: 30.6;Fibroblasts: 44.3;Inhibitory neurons: 95.0;Microglial cells: 28.1;NK-cells: 46.4" "Cancer enhanced" "Detected in all" "renal cancer: 17.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "eosinophil: 9.5;gdT-cell: 16.4;memory CD8 T-cell: 7.2;naive CD8 T-cell: 6.0;NK-cell: 17.1" "Group enriched" "Detected in many" 29 "granulocytes: 9.5;NK-cells: 17.1;T-cells: 16.4" "Group enriched" "Detected in many" 6 "ASC diff: 139.8;HHSteC: 42.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 39.4" "HPA046183, HPA066271" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 95000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA046183: AB_2679573, HPA066271: AB_2685645" "unprognostic (2.21e-1)" "unprognostic (9.35e-2)" "unprognostic (5.60e-2)" "unprognostic (1.72e-1)" "unprognostic (5.81e-2)" "unprognostic (8.83e-2)" "unprognostic (2.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (2.26e-1)" "unprognostic (7.01e-3)" "prognostic unfavorable (9.60e-4)" "unprognostic (1.19e-1)" "unprognostic (6.72e-2)" "unprognostic (3.57e-3)" 20.4 106.5 0.5 3.4 0.8 0.9 21.7 0.7 1.3 25.1 9.0 8.8 4.1 11.8 7.1 1.9 9.3 34.0 23.2 0.8 2.2 7.7 2.3 3.1 7.4 5.1 6.6 78.0 25.7 17.1 13.4 7.0 9.4 10.0 9.8 1.5 8.6 37.4 2.2 7.9 4.8 9.7 1.8 2.8 23.4 3.3 2.0 3.7 18.3 8.8 5.4 15.8 15.4 2.3 0.0 7.8 4.0 0.0 139.8 4.2 0.1 0.9 0.8 0.7 0.8 0.0 1.3 7.4 1.4 7.3 5.2 0.4 0.0 0.2 0.3 0.0 3.2 0.2 1.6 0.3 42.6 0.0 0.1 14.7 0.0 0.1 0.0 0.2 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 1.4 0.0 2.1 0.0 6.7 0.0 0.1 9.6 0.0 13.8 3.2 1.8 0.0 2.0 1.0 0.1 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.8 0.6 0.0 9.5 16.4 0.0 1.4 0.4 1.7 7.2 0.0 0.0 0.2 6.0 0.2 17.1 0.1 0.0 0.1 4.2 0.5 0.8 0.7 1.3 0.8 2.2 5.1 6.6 9.4 1.8 2.0 2.3 15.6 0.0 0.0 1.0 1.6 3.1 7.7 0.2 1.8 2.3 1.7 9.4 4.5 32.9 0.6 5.5 0.0 0.2 30.0 0.2 0.0 30.6 8.2 0.8 1.8 10.3 1.8 1.3 13.9 4.4 0.2 44.3 0.0 1.4 0.0 8.1 2.9 0.0 0.3 26.9 95.0 1.0 0.0 1.3 3.7 13.3 0.3 0.8 0.0 28.1 0.9 1.5 46.4 2.0 2.8 3.0 0.5 2.2 8.4 1.6 0.0 0.3 0.0 0.5 6.6 1.9 3.7 0.4 4.3 0.3 2.0 0.0 10.2 5.2 0.6 3.2 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 46.0 28.9 13.9 40.4 13.7 1.6 40.1 8.1 12.8 50.8 18.1 37.7 22.4 44.3 21.8 22.5 50.9 38.5 32.1 11.9 11.0 26.5 16.0 37.9 8.5 16.7 11.9 190.2 13.4 3.0 3.7 62.7 15.1 15.0 35.2 5.3 16.6 18.9 9.6 14.8 31.3 48.1 12.1 46.2 29.4 13.6 8.9 7.6 16.5 41.9 7.2 63.9 38.0 20.0 0.1 0.0 1.0 0.8 468.1 216.1 0.5 25.4 279.4 0.1 0.7 67.6 0.5 0.5 0.5 195.9 0.8 0.6 19.6 0.2 0.1 2.6 1.0 0.7 0.7 1.2 156.3 0.3 0.4 392.0 0.0 31.4 0.0 5.4 0.0 0.7 0.6 0.9 1.1 0.1 0.4 1.2 3.5 0.3 1.1 0.5 0.1 0.1 0.0 0.4 0.6 37.9 0.0 0.5 0.2 2.0 0.7 0.1 0.8 84.9 3.2 93.9 0.2 0.4 0.1 0.8 2.6 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 13.7 8.1 12.8 11.9 11.0 16.7 11.9 15.1 12.1 8.9 20.0 11.1 0.0 0.5 0.3 0.6 17.1 0.6 2.4 1.2 5.5 4.3 3.2 4.8 0.0 0.8 0.0 0.0 1.4 0.9 0.1 1.9 4.2 2.2 11.7 423.9 5.7 0.0 0.0 1.1 6.7 2.0 256.4 5.1 9.0 0.0 2.6 26.0 1.0 3.1 0.0 19.5 0.2 10.2 0.6 27.3 17.2 449.8 5.4 23.2 39.4 4.7 17.5 0.0 499.6 0.4 20.0 0.0 408.9 0.2 0.9 0.0 0.1 0.5 0.6 0.0 25.7 13.9 1.0 3.4 8.1 15.8 1.4 2.5 49.6 0.0 1.0 PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 1288.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC diff: 1350.1;ASC TERT1: 462.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" 171.2 25.1 25.4 27.5 27.2 0.7 106.3 20.5 33.3 155.9 43.5 41.6 11.9 101.1 24.2 24.1 89.6 124.5 75.7 22.1 23.2 49.7 13.4 98.3 27.5 22.1 24.6 105.5 20.8 21.9 23.0 113.3 22.8 56.2 14.1 6.3 34.5 43.3 38.1 65.0 37.9 68.9 19.4 41.4 27.9 18.4 27.7 8.7 66.5 44.1 13.8 58.3 98.6 21.6 0.1 0.3 8.3 0.4 1350.1 462.7 3.0 48.9 202.3 33.5 56.4 5.4 0.0 0.0 6.4 142.0 19.0 0.1 0.1 0.4 15.8 0.0 0.0 0.1 3.3 3.5 190.7 0.0 0.4 210.0 0.0 46.3 0.6 106.6 0.1 0.1 0.1 5.5 5.5 0.0 0.1 0.6 9.0 0.2 0.2 3.7 2.5 0.2 0.0 0.0 0.1 24.8 0.5 0.1 0.0 38.2 0.1 0.6 0.4 53.7 17.2 23.1 2.8 0.4 0.0 0.3 33.4 0.1 1.5 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.0 0.2 25.4 27.2 20.5 33.3 22.1 23.2 22.1 24.6 22.8 19.4 27.7 21.6 50.8 0.0 1.1 81.9 0.5 24.0 0.5 0.0 2.2 6.6 1.4 3.3 17.3 1.5 0.0 1.8 4.2 0.6 6.0 0.3 0.0 0.8 1.6 2.8 99.5 32.2 0.0 0.0 7.9 0.0 1.1 123.5 2.0 2.3 0.0 2.5 6.4 1.9 1.5 0.0 1.3 0.7 0.0 0.0 35.6 10.9 165.3 3.1 24.9 45.0 0.7 50.7 23.7 10.1 3.3 0.1 0.1 203.8 2.3 0.7 0.3 0.1 0.7 2.9 1288.5 6.6 288.3 1.9 1.6 0.8 15.3 0.8 4.8 4.0 0.4 1.1 PDGFRL PRLTS ENSG00000104213 "Platelet derived growth factor receptor like" Q15198 8 17576433-17644071 "Disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Fibroblasts: 186.2;Leydig cells: 74.6;Peritubular cells: 70.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 189.4;BJ hTERT+: 159.1;HSkMC: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052801 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA052801: AB_2681956" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (5.10e-2)" "unprognostic (1.59e-2)" "unprognostic (7.39e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "unprognostic (3.86e-1)" "unprognostic (7.46e-2)" "unprognostic (1.63e-1)" "unprognostic (6.72e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (4.47e-3)" "unprognostic (6.00e-3)" 34.1 4.2 2.5 3.9 3.5 0.2 51.9 2.8 3.0 27.8 1.9 9.0 0.9 15.8 10.3 3.0 23.3 13.4 11.1 2.3 2.3 1.3 0.7 4.7 1.2 2.7 2.6 42.9 6.9 9.0 7.4 9.0 2.5 5.4 3.1 0.6 13.1 6.7 18.4 11.0 2.6 26.0 2.4 0.8 6.2 6.5 2.9 3.8 33.0 38.0 2.0 6.5 12.0 3.3 0.0 17.7 1.0 189.4 5.6 2.5 13.8 4.6 159.1 7.5 31.3 1.0 0.2 0.0 0.9 2.5 24.7 0.0 11.6 0.9 3.7 0.2 14.5 0.0 5.3 4.1 14.6 0.0 0.0 86.9 0.1 9.2 0.1 0.0 13.0 1.6 0.0 2.4 1.1 12.5 0.2 0.4 9.9 0.7 3.6 0.0 0.2 0.4 1.0 11.4 0.6 1.2 1.4 1.7 3.3 11.4 0.6 0.0 2.6 0.2 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.5 2.8 3.0 2.3 2.3 2.7 2.6 2.5 2.4 2.9 3.3 15.5 0.0 3.6 2.3 0.3 13.3 0.5 4.3 0.6 0.6 2.9 3.3 4.5 1.5 2.8 0.0 0.0 14.9 0.7 0.4 0.0 4.1 36.0 2.4 5.4 4.1 1.2 0.0 1.1 7.1 19.9 186.2 0.5 4.7 0.0 0.3 1.4 0.2 3.5 0.0 3.5 1.3 2.0 0.0 14.6 6.7 74.6 1.6 10.6 1.9 1.6 1.4 0.0 3.0 1.3 3.1 0.1 70.7 0.2 1.9 0.4 0.1 0.2 0.4 0.0 8.0 10.7 0.8 1.9 0.6 9.9 9.7 1.7 1.5 0.4 0.5 PDHA1 PDHA ENSG00000131828 "Pyruvate dehydrogenase E1 subunit alpha 1" P08559 X 19343893-19361718 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 508.8;tongue: 770.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 479.9;Distal tubular cells: 354.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria "Intracellular and membrane" NA NA 100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047487: AB_2680066, HPA047864: AB_2680190, HPA063053: AB_2684931" "unprognostic (5.71e-3)" "unprognostic (2.46e-3)" "unprognostic (5.71e-2)" "unprognostic (3.36e-3)" "unprognostic (3.12e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-2)" "unprognostic (4.28e-1)" "unprognostic (1.01e-1)" "unprognostic (7.01e-3)" "unprognostic (6.90e-2)" "unprognostic (8.68e-2)" "prognostic favorable (1.13e-7)" "unprognostic (3.72e-2)" "unprognostic (3.03e-1)" "unprognostic (1.92e-2)" "unprognostic (9.06e-2)" 93.0 69.0 62.1 37.9 66.9 88.1 63.1 66.2 91.5 55.9 84.4 112.6 87.0 53.1 78.9 76.8 49.1 29.3 508.8 68.2 67.0 174.1 118.3 47.2 36.6 64.5 62.7 50.6 83.4 161.0 48.7 43.1 65.0 48.4 104.4 90.1 109.7 63.4 459.0 60.9 82.1 51.8 59.6 49.3 121.8 24.0 67.4 52.3 64.5 770.2 59.1 61.7 56.1 71.1 124.9 151.4 107.9 114.2 102.3 77.7 131.6 83.8 74.6 170.2 130.7 216.6 78.2 212.2 60.6 102.0 226.7 159.0 334.2 145.8 178.1 70.1 186.1 104.8 264.0 194.2 107.8 170.3 82.8 100.9 132.8 157.3 154.4 85.6 105.3 129.8 94.2 87.2 120.7 164.5 142.7 173.5 110.0 227.4 261.7 145.2 180.9 260.3 298.0 125.1 59.7 62.6 134.1 167.8 158.1 229.8 177.1 118.1 65.4 87.6 78.6 240.9 108.6 73.3 82.0 140.5 82.4 117.2 77.4 99.9 87.4 65.3 72.3 119.9 88.9 103.4 69.4 79.5 115.7 82.1 67.7 72.0 15.5 98.1 109.1 76.9 84.4 89.6 62.1 66.9 66.2 91.5 68.2 67.0 64.5 62.7 65.0 59.6 67.4 71.1 34.1 44.8 44.4 18.6 30.7 29.8 59.7 135.4 25.0 59.0 37.0 29.3 479.9 87.2 74.8 152.6 33.3 105.0 32.5 73.0 354.1 88.8 2.5 41.2 33.7 36.8 41.9 55.8 21.2 59.8 120.7 49.2 49.5 36.9 42.6 39.7 18.2 76.3 73.2 25.2 24.6 64.4 71.2 26.8 30.5 4.1 35.4 32.5 56.9 9.4 40.8 49.0 26.8 13.0 11.5 47.4 52.5 40.6 43.3 47.1 88.6 213.7 33.1 69.1 32.9 37.5 51.7 51.1 25.3 45.2 33.4 133.4 31.6 25.4 130.3 55.8 PDIA2 "PDA2, PDI, PDIP, PDIR" ENSG00000185615 "Protein disulfide isomerase family A member 2" Q13087 16 283164-287215 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "pancreas: 2509.7" "Cell type enriched" "Detected in some" 4 "Exocrine glandular cells: 294.9" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.9;HEK 293: 7.9;Hep G2: 6.7;Karpas-707: 2.9;MCF7: 4.6;SH-SY5Y: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051692, HPA053492" Enhanced "Intracellular and membrane" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" "HPA051692: AB_2681575, HPA053492: AB_2682169" "unprognostic (3.46e-2)" "unprognostic (7.98e-3)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" "unprognostic (2.17e-2)" "unprognostic (6.27e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-1)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (2.90e-2)" "unprognostic (1.58e-14)" "unprognostic (3.06e-2)" "unprognostic (1.66e-1)" "unprognostic (8.75e-2)" "unprognostic (2.87e-2)" 2.8 0.6 64.4 0.4 70.1 0.6 0.8 80.5 96.0 0.6 61.2 2.7 23.9 0.3 0.9 0.9 0.7 0.1 4.4 64.2 66.7 0.6 0.6 0.7 0.2 76.6 67.1 1.5 2509.7 0.0 7.6 2.5 73.2 1.0 0.3 2.4 1.0 0.1 0.6 0.4 7.1 0.0 69.9 0.3 191.7 1.0 68.7 0.0 0.4 0.0 0.5 0.5 0.6 88.5 0.0 1.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.1 0.1 3.9 0.1 0.5 0.0 7.9 0.0 0.3 6.7 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.1 0.0 0.3 2.9 0.1 4.6 0.1 0.4 0.2 1.6 0.0 0.1 0.0 0.9 0.0 0.0 1.6 3.7 0.0 0.1 0.0 0.5 1.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.4 70.1 80.5 96.0 64.2 66.7 76.6 67.1 73.2 69.9 68.7 88.5 0.0 0.0 0.5 1.6 1.9 0.5 0.0 0.0 0.0 4.2 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.1 0.3 0.1 0.0 0.0 12.4 294.9 1.3 5.5 65.7 0.1 0.0 0.1 0.0 0.0 0.4 0.0 14.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.9 1.6 0.6 0.0 2.0 22.2 25.5 1.4 0.4 0.2 0.0 3.9 1.1 0.0 0.5 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.5 0.0 0.0 1.4 0.0 PDIA3 "ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC" ENSG00000167004 "Protein disulfide isomerase family A member 3" P30101 15 43746410-43773278 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1048.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002645, HPA003230, CAB011199, CAB015181, CAB075744" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 200000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB011199: AB_609902, CAB015181: AB_2160857, CAB075744: AB_2665750, HPA002645: AB_1079031, HPA003230: AB_1079030" "unprognostic (9.20e-2)" "unprognostic (1.21e-3)" "unprognostic (1.34e-1)" "prognostic favorable (2.05e-4)" "unprognostic (2.40e-2)" "prognostic unfavorable (8.95e-5)" "unprognostic (1.67e-1)" "unprognostic (8.60e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.11e-8)" "unprognostic (1.82e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (6.63e-2)" 17.0 16.6 7.5 16.5 8.0 27.1 15.6 9.2 7.6 24.7 13.9 20.6 23.6 16.4 44.7 18.9 15.4 13.5 17.3 7.7 9.8 15.3 34.5 16.8 18.7 9.3 8.2 16.5 36.0 22.6 16.2 23.8 9.1 25.2 22.5 8.4 21.6 19.1 7.6 17.3 21.4 17.0 9.0 12.5 20.4 10.8 9.3 9.6 56.0 4.1 12.3 15.6 15.2 9.8 29.4 11.9 24.6 55.1 48.9 51.9 70.8 58.6 62.1 46.0 56.7 33.6 32.1 33.8 37.4 72.9 30.8 47.8 31.8 61.5 39.7 24.3 44.7 47.2 17.6 30.9 80.1 26.0 33.8 33.6 49.8 35.0 58.5 54.0 81.3 11.1 27.7 17.4 45.5 11.1 9.1 30.4 24.4 48.5 44.0 17.9 36.7 26.2 39.3 26.0 22.9 25.4 48.7 49.0 19.4 25.0 33.1 28.1 50.9 37.7 18.9 29.7 29.1 7.1 8.6 33.9 48.1 41.2 28.8 11.6 8.8 13.3 12.1 9.2 12.8 5.4 6.8 9.5 8.3 6.1 6.0 7.1 2.4 12.7 9.9 17.6 5.8 15.8 7.5 8.0 9.2 7.6 7.7 9.8 9.3 8.2 9.1 9.0 9.3 9.8 224.9 192.3 183.9 31.6 177.8 192.2 313.7 665.2 114.4 56.5 137.9 95.5 58.3 124.4 427.7 167.3 41.7 655.2 319.6 228.7 70.5 401.2 24.3 178.8 300.3 223.7 186.1 95.3 29.2 390.4 807.8 350.7 261.0 328.5 261.6 255.1 233.1 342.2 426.0 70.7 38.3 523.1 231.9 157.3 292.2 26.7 253.5 246.5 243.7 36.5 258.0 128.3 279.1 29.7 38.8 279.9 196.8 276.8 341.1 286.5 234.3 129.1 245.6 61.9 124.9 138.4 389.7 186.4 147.6 138.9 148.5 1048.8 237.8 390.8 335.4 291.7 PDIA4 "ERP70, ERP72" ENSG00000155660 "Protein disulfide isomerase family A member 4" P13667 7 149003062-149028662 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 386.7;Hepatocytes: 595.4;Plasma cells: 556.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006139, HPA006140, CAB017368" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 15000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB017368: AB_10621725, HPA006139: AB_1848256, HPA006140: AB_1848257" "unprognostic (1.98e-1)" "unprognostic (1.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (9.69e-4)" "unprognostic (1.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.11e-2)" "unprognostic (5.11e-2)" "unprognostic (3.24e-3)" "unprognostic (6.08e-3)" "unprognostic (3.20e-2)" "prognostic unfavorable (5.20e-9)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" 50.3 30.0 22.8 91.5 27.5 35.7 38.2 31.1 24.1 92.8 33.6 84.8 74.1 58.6 163.5 38.9 81.6 53.5 40.4 22.1 31.2 49.5 241.7 48.5 59.0 35.3 29.3 47.3 112.6 26.4 44.6 92.0 34.2 69.3 85.5 8.4 56.1 47.4 9.3 30.0 66.3 71.9 29.6 63.6 95.6 30.8 33.8 46.7 234.1 10.1 72.4 65.6 33.3 49.8 251.3 236.0 249.8 703.3 223.2 158.2 358.2 343.5 230.5 194.8 314.5 196.6 661.5 179.4 748.2 287.0 532.2 160.1 170.6 329.1 168.9 129.0 99.0 86.6 62.7 436.6 298.4 198.5 233.9 156.4 145.1 213.6 169.8 251.7 401.0 90.6 143.6 476.1 173.4 276.4 190.9 226.0 371.1 510.9 134.0 123.6 192.5 440.5 228.2 194.9 79.1 207.6 313.0 223.7 124.1 295.7 127.4 151.9 220.6 152.1 84.5 372.0 247.5 357.5 173.7 125.5 354.2 231.1 528.9 74.4 80.5 51.0 130.4 85.6 135.4 99.1 83.7 100.8 77.6 58.2 77.4 82.7 11.0 91.9 91.4 251.8 68.7 160.6 22.8 27.5 31.1 24.1 22.1 31.2 35.3 29.3 34.2 29.6 33.8 49.8 43.3 28.9 36.2 6.8 87.9 34.7 88.0 142.5 29.0 4.2 50.8 31.5 31.0 95.8 92.4 42.3 4.2 177.8 86.9 135.4 15.6 129.0 3.1 91.1 93.1 57.0 61.6 41.2 3.2 91.0 386.7 102.8 119.8 107.1 57.8 72.0 81.4 595.4 147.9 0.0 5.7 282.9 61.1 84.7 49.6 5.5 59.0 55.3 87.2 9.4 51.8 15.6 68.0 4.5 11.9 94.5 88.6 42.9 556.7 108.1 71.3 66.3 114.8 6.7 32.9 35.2 66.0 47.6 86.1 29.2 28.6 230.4 46.7 52.4 155.6 72.4 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 4700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 17.9 23.6 0.3 15.2 0.3 17.9 13.8 0.2 1.4 14.5 2.7 20.1 13.9 12.4 30.2 6.1 14.0 19.6 9.9 0.6 0.8 14.5 80.2 17.7 11.1 0.5 0.6 11.5 26.6 10.7 12.7 47.4 0.4 32.3 25.0 4.2 13.7 7.9 4.2 8.8 12.8 17.0 0.3 10.1 33.4 15.3 0.9 4.5 30.8 4.3 12.0 17.9 9.5 0.7 24.0 14.6 17.7 21.5 80.3 71.9 95.0 44.9 74.5 24.5 66.9 47.8 21.6 0.0 57.6 69.9 15.7 12.5 7.8 27.4 25.7 1.1 8.8 10.4 3.9 56.7 33.2 26.5 1.4 62.3 40.2 16.6 34.5 26.1 84.0 10.1 13.6 60.4 16.9 29.6 7.2 31.3 13.1 54.5 15.6 6.7 13.0 67.5 20.7 13.9 19.3 11.4 22.0 24.0 40.4 28.7 21.4 32.3 47.2 6.2 19.5 29.4 12.3 18.1 5.0 10.8 20.2 21.0 21.5 0.0 9.3 0.3 1.4 2.4 2.3 3.5 1.0 0.8 5.5 1.1 0.6 0.6 0.2 0.5 0.5 12.8 0.0 2.3 0.3 0.3 0.2 1.4 0.6 0.8 0.5 0.6 0.4 0.3 0.9 0.7 17.2 19.2 30.7 2.6 5.6 5.0 6.0 6.4 3.4 13.1 6.9 4.7 2.7 35.8 11.3 5.5 39.6 41.8 3.1 5.4 0.0 32.2 1.6 5.4 13.1 24.3 8.4 5.5 9.6 28.6 133.6 20.7 30.5 21.1 3.8 7.3 37.5 50.1 12.1 0.0 7.1 36.9 0.0 7.8 5.5 2.0 24.2 4.4 8.8 5.6 5.0 2.3 0.0 1.0 2.5 11.9 7.6 22.2 40.1 18.1 3.5 5.3 6.4 28.4 13.1 3.6 17.6 1.3 1.5 3.4 4.1 50.2 3.1 23.3 15.1 4.5 PDIA6 "ERp5, P5, TXNDC7" ENSG00000143870 "Protein disulfide isomerase family A member 6" Q15084 2 10783391-10837977 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1202.1;Plasma cells: 883.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034347, HPA034652, HPA034653" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 15000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Cytosol" "CAB034347: AB_2299360, HPA034652: AB_2674263, HPA034653: AB_10601982" "unprognostic (8.16e-2)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.20e-4)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" "unprognostic (5.25e-3)" "unprognostic (6.03e-3)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (6.59e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-2)" "unprognostic (3.69e-3)" 118.3 112.3 54.5 155.8 64.6 140.8 124.9 57.1 66.7 178.8 71.2 156.0 122.4 131.6 418.5 98.2 133.5 96.7 113.4 55.9 60.8 130.3 260.5 103.8 118.1 61.1 55.4 99.8 252.1 149.7 74.0 171.3 60.7 127.4 171.6 48.0 184.1 135.5 59.3 64.3 121.5 155.5 60.9 107.4 155.4 55.1 62.6 86.6 363.3 59.4 153.7 130.9 75.7 66.4 287.0 304.6 425.7 672.6 535.6 459.4 753.4 677.8 625.9 348.3 465.1 435.1 548.5 460.9 464.7 668.9 674.1 228.0 324.1 568.3 371.1 363.2 253.4 374.2 228.4 713.2 577.5 387.9 268.9 334.2 428.4 338.1 603.3 642.1 798.0 171.8 328.0 963.6 348.7 338.8 150.5 400.8 356.6 923.4 236.4 355.7 433.0 846.4 498.3 339.9 272.0 543.2 267.6 387.0 396.2 547.8 136.8 648.5 395.0 324.4 409.8 296.3 399.1 900.0 596.6 297.1 438.5 479.6 464.8 276.1 200.0 95.5 198.4 210.9 219.0 197.6 154.2 187.6 215.0 161.0 74.3 125.1 35.0 241.6 161.4 268.9 174.4 319.2 54.5 64.6 57.1 66.7 55.9 60.8 61.1 55.4 60.7 60.9 62.6 66.4 217.1 57.7 124.2 17.6 193.9 103.0 294.2 552.8 61.5 69.1 121.1 91.7 35.9 148.7 264.6 196.8 29.2 456.3 164.6 125.8 43.0 338.6 8.2 146.5 382.9 176.2 157.7 89.2 47.4 240.6 1202.1 228.2 138.1 255.0 131.3 210.6 211.3 355.6 413.1 42.1 30.5 276.3 170.9 155.7 149.8 16.2 121.2 145.9 199.3 15.0 132.1 106.5 142.2 32.6 25.3 175.4 131.2 135.1 883.2 385.4 99.9 149.6 145.8 60.1 85.5 96.9 225.3 98.5 117.9 95.4 102.6 554.1 125.7 254.3 248.3 265.3 PDILT PDIA7 ENSG00000169340 "Protein disulfide isomerase like, testis expressed" Q8N807 16 20359175-20404737 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Chaperone, Developmental protein, Isomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "stomach 1: 122.7" "Cell type enriched" "Detected in some" 5 "Early spermatids: 136.9" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 1.0;HBEC3-KT: 3.0;hTCEpi: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA041913 Approved "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 4: Stomach - Digestion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" "HPA041913: AB_10795644" "unprognostic (1.99e-1)" "unprognostic (6.09e-2)" "unprognostic (2.05e-3)" "unprognostic (2.63e-1)" 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.1 122.7 18.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 3.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.2 0.2 3.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.1 0.1 0.1 0.0 0.5 0.2 0.2 0.0 0.3 0.1 0.2 0.5 0.7 0.1 2.8 0.0 0.2 0.1 0.2 0.1 0.3 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136.9 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 23.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PDPR PDP3 ENSG00000090857 "Pyruvate dehydrogenase phosphatase regulatory subunit" Q8NCN5 16 70114332-70162537 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048092, HPA070386" Uncertain Approved Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria "HPA048092: AB_2680261, HPA070386: AB_2686263" "unprognostic (8.30e-2)" "unprognostic (1.32e-1)" "unprognostic (7.91e-2)" "unprognostic (1.52e-1)" "unprognostic (2.57e-1)" "unprognostic (9.04e-3)" "unprognostic (6.81e-2)" "unprognostic (2.67e-1)" "unprognostic (1.41e-1)" "unprognostic (1.18e-2)" "unprognostic (2.55e-1)" "unprognostic (2.90e-1)" "prognostic favorable (8.36e-4)" "unprognostic (8.85e-2)" "unprognostic (1.96e-2)" "unprognostic (2.17e-1)" "unprognostic (6.24e-2)" 11.5 12.6 10.7 8.1 13.3 15.9 11.3 14.7 11.4 13.1 9.8 14.5 9.1 14.1 11.9 8.1 12.8 6.7 14.7 10.7 11.4 16.3 8.6 9.6 11.1 11.8 12.4 13.5 12.3 10.2 10.4 9.0 11.8 10.9 11.8 12.1 10.3 9.6 23.2 12.2 13.7 15.1 10.6 15.4 12.0 19.1 12.5 15.8 13.0 13.6 12.5 13.8 9.8 13.9 6.9 19.4 17.9 33.0 32.6 20.9 12.1 11.1 19.4 17.4 13.1 25.1 13.4 14.4 19.1 35.8 16.1 26.7 26.4 24.1 20.3 3.5 9.1 35.8 12.7 17.6 9.3 39.9 27.9 28.0 22.6 25.1 23.0 25.2 18.7 26.6 24.6 6.6 15.3 20.8 25.3 23.3 27.8 4.9 10.0 49.0 18.5 14.9 13.8 16.3 8.3 12.3 30.2 6.2 8.2 24.2 24.4 12.4 10.9 20.4 27.3 17.6 17.9 15.4 17.9 50.9 9.1 13.8 13.5 1.6 1.5 1.4 1.4 1.5 2.0 0.9 1.1 1.3 1.6 1.5 1.3 1.5 1.1 0.9 1.5 1.5 1.3 1.0 10.7 13.3 14.7 11.4 10.7 11.4 11.8 12.4 11.8 10.6 12.5 13.9 12.6 22.4 18.2 18.6 13.0 2.8 4.9 3.5 18.2 21.6 14.2 12.1 19.2 17.2 9.1 1.8 31.3 7.7 16.0 12.1 5.9 5.3 54.4 13.7 16.0 17.4 4.9 17.4 18.0 6.7 7.8 16.1 11.7 17.1 18.3 23.9 17.2 11.2 16.4 32.0 20.3 10.0 4.1 17.8 3.5 20.8 10.8 15.7 7.2 10.3 12.2 11.2 15.5 9.5 13.9 6.8 6.1 16.6 11.7 10.3 11.6 4.4 12.7 20.8 19.7 22.7 11.5 10.8 15.4 11.1 1.8 4.9 11.9 12.7 14.5 4.6 PDXP "CIN, dJ37E16.5, FLJ32703" ENSG00000241360 "Pyridoxal phosphatase" Q96GD0 22 37658723-37666932 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 209.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 19.4;Inhibitory neurons: 25.0;Microglial cells: 7.5;Oligodendrocyte precursor cells: 8.0;Oligodendrocytes: 5.8;Plasma cells: 9.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "plasmacytoid DC: 11.6" "Lineage enriched" "Detected in many" 8 "dendritic cells: 11.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000531 Approved NA NA 94000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA000531: AB_2666018" "unprognostic (6.29e-2)" "unprognostic (7.89e-3)" "unprognostic (1.00e-1)" "unprognostic (2.89e-1)" "unprognostic (2.15e-2)" "unprognostic (3.25e-2)" "unprognostic (2.81e-1)" "unprognostic (4.44e-2)" "unprognostic (2.54e-1)" "unprognostic (1.46e-1)" "unprognostic (1.57e-3)" "unprognostic (2.76e-2)" "unprognostic (1.77e-1)" "unprognostic (3.03e-3)" "unprognostic (2.04e-1)" "unprognostic (4.66e-2)" "unprognostic (2.38e-1)" 5.8 23.7 144.7 0.8 158.7 5.8 5.3 106.1 209.2 6.7 83.0 20.6 26.5 8.5 5.6 3.8 8.0 3.9 26.3 165.0 129.2 15.9 74.5 5.7 7.5 117.5 130.0 8.5 13.5 9.5 39.6 1.1 119.8 7.3 11.6 29.6 12.0 6.0 15.8 3.4 32.2 7.2 109.2 14.3 11.9 27.0 137.8 13.5 5.9 14.1 9.5 7.8 3.8 148.0 8.6 19.6 39.4 34.4 12.0 3.7 5.3 18.9 9.7 34.0 26.7 9.9 1.2 54.0 18.8 9.8 28.5 4.4 52.8 0.6 28.5 16.9 105.2 11.0 26.6 41.2 8.3 39.2 47.0 1.8 4.7 17.6 23.7 14.0 15.6 61.1 33.3 31.1 29.9 12.3 74.3 61.3 20.6 15.2 46.4 58.5 28.5 39.7 14.6 1.1 89.5 57.8 17.8 15.4 36.1 17.2 5.0 31.8 9.8 28.7 36.6 30.2 37.6 33.0 44.1 57.4 27.2 14.3 38.5 0.0 0.3 0.5 0.9 0.5 0.1 1.3 0.4 0.5 0.6 1.2 0.3 0.1 0.3 0.9 0.4 11.6 0.5 0.2 144.7 158.7 106.1 209.2 165.0 129.2 117.5 130.0 119.8 109.2 137.8 148.0 0.1 0.0 0.6 3.3 2.8 0.0 0.0 0.0 2.8 1.0 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.2 0.4 0.1 0.0 2.1 19.4 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 25.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 7.5 0.1 0.2 0.0 8.0 5.8 0.1 0.1 0.0 9.7 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.9 0.2 0.4 0.1 PDYN "ADCA, PENKB, SCA23" ENSG00000101327 Prodynorphin P01213 20 1978757-1994285 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Neurotransmitter, Opioid peptide" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 47.0" "Group enriched" "Detected in some" 83 "Early spermatids: 47.8;Late spermatids: 119.0" "Group enriched" "Detected in some" 29 "glioma: 2.6;ovarian cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "THP-1: 1.0" "Group enriched" "Detected in many" 4 "basal ganglia: 152.2;hypothalamus: 60.7" "Region enhanced" "Detected in many" "basal ganglia: 132.2" "HPA053342, CAB079777" Enhanced Supported "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "CAB079777: , HPA053342: AB_2682121" "unprognostic (7.00e-2)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" "unprognostic (3.73e-2)" 0.0 0.0 43.2 0.1 31.1 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.0 17.6 0.0 0.0 0.0 0.0 1.8 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 21.0 0.0 0.0 8.3 9.2 0.2 0.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.2 31.1 0.0 43.1 47.0 17.6 1.8 4.1 0.2 21.0 9.2 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 119.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PDZD8 "bA129M16.2, FLJ34427, PDZK8" ENSG00000165650 "PDZ domain containing 8" Q8NEN9 10 117277274-117375440 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.0" "Cell type enhanced" "Detected in all" "Early spermatids: 208.7;Late spermatids: 477.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 124.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015716, HPA051610" Uncertain Approved "Nucleoli fibrillar center,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Plasma membrane" "HPA015716: AB_1855162, HPA051610: AB_2681549" "unprognostic (1.12e-1)" "unprognostic (2.87e-1)" "unprognostic (9.65e-3)" "unprognostic (2.75e-2)" "unprognostic (6.29e-2)" "unprognostic (3.36e-2)" "unprognostic (2.42e-1)" "unprognostic (1.43e-1)" "unprognostic (2.53e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.90e-2)" "unprognostic (5.37e-3)" "unprognostic (7.60e-3)" "unprognostic (1.44e-2)" "unprognostic (3.18e-2)" "unprognostic (2.01e-2)" 7.1 7.0 8.9 4.7 12.1 73.0 4.7 15.7 8.6 7.9 17.9 9.3 14.0 9.1 14.1 10.8 6.8 9.7 5.1 8.1 11.8 13.1 15.8 6.0 3.2 11.9 13.8 8.9 14.1 28.3 4.2 5.4 12.2 6.4 11.2 14.1 12.9 10.6 4.9 5.5 10.6 6.9 11.3 3.7 10.4 13.2 12.5 5.8 6.8 5.8 3.6 6.6 5.8 13.2 12.6 21.1 7.6 14.7 12.8 11.4 4.3 11.9 10.2 5.2 4.2 10.7 16.4 14.7 10.5 18.1 6.0 18.4 13.4 12.6 10.3 9.4 11.8 124.3 8.6 10.6 9.4 52.4 11.2 11.2 14.7 9.5 27.9 19.3 9.3 12.1 11.5 15.0 13.0 5.1 10.2 6.7 6.0 6.6 18.8 8.2 29.2 6.4 15.5 9.0 6.0 9.6 12.6 5.4 9.7 6.9 3.7 7.6 15.1 8.6 9.4 15.8 20.5 8.0 7.2 10.5 10.8 23.6 7.7 1.4 0.5 2.6 0.9 0.5 0.9 0.3 0.7 0.7 0.7 0.4 0.5 0.7 2.3 1.2 0.9 0.5 0.3 0.2 8.9 12.1 15.7 8.6 8.1 11.8 11.9 13.8 12.2 11.3 12.5 13.2 22.1 12.8 30.7 32.3 13.7 29.7 24.4 10.3 24.5 31.9 16.4 17.0 19.8 40.0 21.0 18.4 22.9 9.8 36.1 26.9 9.8 31.9 208.7 78.3 46.7 24.0 33.7 82.0 49.2 81.9 7.2 27.3 48.4 111.2 44.2 14.6 18.9 58.6 7.5 32.0 61.0 38.8 10.2 16.0 31.8 477.6 23.6 25.2 23.2 30.0 15.5 29.0 23.7 51.8 56.4 57.6 23.1 28.6 28.1 41.1 27.0 26.5 28.5 45.0 26.3 46.3 24.5 25.8 29.1 36.3 32.4 6.7 28.4 90.8 50.2 44.6 PDZRN4 "DKFZp434B0417, FLJ33777, IMAGE5767589, LNX4" ENSG00000165966 "PDZ domain containing ring finger 4" Q6ZMN7 12 41188320-41574745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.9;seminal vesicle: 17.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 371.6;Inhibitory neurons: 125.6;Oligodendrocyte precursor cells: 561.9" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "U-266/70: 4.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042101 Enhanced Approved Mitochondria NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA042101: AB_2732496" "unprognostic (6.74e-2)" "unprognostic (6.86e-2)" "unprognostic (3.82e-2)" "unprognostic (2.88e-2)" "unprognostic (1.49e-1)" "unprognostic (5.34e-2)" "unprognostic (2.48e-2)" "unprognostic (1.38e-2)" "unprognostic (8.19e-2)" "unprognostic (7.85e-3)" "unprognostic (1.69e-1)" "unprognostic (2.42e-1)" "unprognostic (7.44e-2)" "unprognostic (1.90e-3)" "unprognostic (1.80e-1)" "unprognostic (7.33e-2)" "unprognostic (1.41e-3)" 1.2 0.9 1.5 1.1 2.5 0.0 1.9 0.1 2.3 2.2 0.0 10.9 0.8 0.9 2.2 3.8 2.2 1.7 0.4 1.5 0.9 0.5 0.6 0.3 0.0 1.3 3.3 1.9 0.4 0.1 0.4 4.0 2.2 6.6 3.1 1.0 0.3 17.8 0.3 0.5 2.9 2.5 1.3 0.2 3.3 2.4 1.4 0.0 0.3 1.9 0.3 3.9 2.6 1.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.5 0.1 2.3 1.5 0.9 1.3 3.3 2.2 1.3 1.4 1.9 0.1 0.0 0.0 37.5 0.3 0.8 0.0 0.0 2.8 9.8 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.4 0.3 0.0 0.0 371.6 0.0 0.2 17.3 1.1 0.0 0.0 19.8 1.4 0.0 0.4 0.0 125.6 0.0 0.0 0.0 0.3 1.6 28.0 0.2 0.0 5.6 0.0 0.4 0.0 561.9 13.7 0.0 0.0 56.4 1.2 0.1 0.0 0.0 0.7 1.1 0.0 0.1 5.7 0.1 0.2 0.8 0.6 0.4 0.0 34.1 0.0 0.1 PEAR1 "FLJ00193, JEDI, MEGF12" ENSG00000187800 "Platelet endothelial aggregation receptor 1" Q5VY43 1 156893698-156916434 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.6;Endothelial cells: 30.6;Hepatic stellate cells: 40.0;Leydig cells: 44.4;Peritubular cells: 35.7;Sertoli cells: 26.3;Smooth muscle cells: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 19.5;HBEC3-KT: 29.9;HHSteC: 21.6;HUVEC TERT2: 52.2;TIME: 85.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035217 Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA 62000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cell Junctions" Centrosome "HPA035217: AB_10669902" "unprognostic (1.02e-1)" "unprognostic (1.84e-5)" "unprognostic (4.77e-2)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.48e-1)" "unprognostic (5.62e-2)" "unprognostic (5.93e-2)" "unprognostic (1.04e-2)" "unprognostic (3.99e-1)" "unprognostic (2.17e-1)" "unprognostic (5.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.20e-2)" "unprognostic (3.37e-3)" "unprognostic (8.51e-2)" "unprognostic (2.64e-2)" 19.0 5.0 2.5 2.3 3.0 2.3 12.9 1.2 4.1 12.3 2.0 4.5 1.6 10.0 1.1 2.6 9.1 7.4 8.7 1.2 1.7 4.8 2.1 11.8 3.8 2.0 2.3 9.1 2.3 1.7 3.4 11.7 2.3 4.7 0.9 0.4 2.9 3.7 5.7 4.2 4.1 4.6 1.1 7.0 3.7 3.0 2.9 1.4 9.7 7.6 1.1 6.0 7.3 1.4 0.5 2.9 0.8 0.0 0.0 3.7 0.1 11.7 19.5 4.8 2.8 0.3 0.5 0.0 0.6 8.7 0.4 0.2 0.0 29.9 1.3 0.2 0.0 14.8 0.7 0.8 21.6 0.1 0.0 11.3 0.1 6.5 1.5 1.0 52.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 6.9 0.0 0.0 85.2 0.1 6.4 2.6 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.5 3.0 1.2 4.1 1.2 1.7 2.0 2.3 2.3 1.1 2.9 1.4 44.6 0.0 3.2 0.0 0.4 0.9 0.1 0.7 1.2 2.4 0.6 1.3 7.5 1.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 1.2 0.2 2.5 30.6 1.8 5.7 0.0 0.4 0.1 10.1 1.5 0.4 1.3 0.1 40.0 0.4 0.5 0.0 0.0 2.3 0.0 1.6 1.5 3.5 44.4 3.0 5.4 12.2 0.4 0.2 0.0 0.0 0.0 1.2 0.0 35.7 0.0 0.2 0.0 0.1 0.2 0.2 26.3 1.7 34.2 1.5 1.5 0.2 1.1 0.3 0.3 1.1 0.3 0.2 PEBP4 "CORK1, hPEBP4, MGC22776" ENSG00000134020 "Phosphatidylethanolamine binding protein 4" Q96S96 8 22713251-23000000 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 382.5;skeletal muscle: 670.8;tongue: 581.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 109.0;Alveolar cells type 2: 177.3;Cardiomyocytes: 144.7;Muller glia cells: 198.7" "Group enriched" "Detected in many" 13 "lung cancer: 11.4;prostate cancer: 23.7;thyroid cancer: 35.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "U-266/70: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA025064 Uncertain "Secreted in other tissues" NA NA 190000000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "HPA025064: AB_1855174" "unprognostic (1.34e-2)" "unprognostic (2.97e-2)" "unprognostic (4.11e-2)" "unprognostic (3.66e-1)" "unprognostic (3.35e-1)" "unprognostic (4.78e-2)" "unprognostic (1.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.60e-1)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "unprognostic (8.76e-3)" "unprognostic (9.70e-8)" "unprognostic (1.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.48e-1)" "unprognostic (4.59e-1)" 1.1 3.4 12.3 0.3 16.7 0.0 3.3 21.2 9.2 0.6 19.2 0.6 0.0 0.5 382.5 6.8 2.2 1.1 200.7 8.5 15.8 2.6 0.9 115.1 0.7 15.6 20.3 1.7 34.5 82.6 13.2 0.3 20.2 45.8 0.2 12.9 21.1 2.8 670.8 1.4 0.6 0.4 8.7 0.8 9.2 6.6 28.7 1.2 56.7 581.4 1.6 0.3 0.5 15.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 12.3 16.7 21.2 9.2 8.5 15.8 15.6 20.3 20.2 8.7 28.7 15.5 1.5 109.0 177.3 15.3 2.2 1.9 1.0 0.1 0.0 10.2 5.7 4.7 144.7 0.0 7.4 1.8 2.1 0.8 1.4 0.3 3.9 0.0 34.8 1.7 2.0 2.4 0.0 0.0 10.0 9.3 0.2 10.1 2.0 7.0 7.6 0.4 3.9 0.7 1.2 10.1 9.6 0.3 2.0 0.0 0.8 28.4 3.4 1.4 1.8 6.5 0.1 198.7 5.2 6.6 0.9 0.3 0.1 10.9 1.5 23.8 0.5 5.9 2.9 8.6 0.0 25.2 2.1 14.8 1.2 0.0 0.9 0.0 1.6 1.1 0.3 1.0 PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Cell type enhanced" "Detected in many" "Adipocytes: 672.9;Endothelial cells: 468.2;Hepatic stellate cells: 275.3;Macrophages: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 773.0;TIME: 537.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" 195.6 21.4 20.3 78.9 21.4 35.5 128.5 21.9 25.3 54.9 21.7 37.9 29.7 51.1 9.2 54.3 45.1 88.6 70.3 18.0 22.2 43.6 22.4 204.9 68.0 24.7 23.1 10.7 21.3 29.9 9.7 455.1 24.1 23.5 37.7 4.0 33.4 24.5 35.7 36.2 39.4 83.5 26.3 94.9 30.9 5.0 28.1 62.4 69.8 97.0 60.4 84.0 35.7 22.2 0.1 0.3 1.3 0.1 1.1 1.5 0.4 0.2 0.3 0.0 0.1 4.7 0.1 4.2 121.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 95.0 1.8 2.2 3.7 0.5 0.3 0.3 0.0 0.8 0.2 1.6 773.0 34.1 2.3 57.8 0.1 0.4 33.3 8.1 0.1 0.0 9.1 1.4 15.3 3.8 0.0 0.1 0.4 0.3 1.8 0.0 0.1 0.2 0.0 48.5 537.8 0.8 0.5 0.9 0.2 3.4 6.3 6.8 1.6 6.7 0.1 54.8 263.9 219.2 19.8 419.6 18.9 26.7 2.2 46.6 154.0 32.7 36.3 68.6 392.0 40.3 702.3 88.6 2.1 224.2 20.3 21.4 21.9 25.3 18.0 22.2 24.7 23.1 24.1 26.3 28.1 22.2 672.9 16.0 37.9 0.7 24.4 0.0 0.5 0.0 4.0 0.0 4.8 4.6 23.3 1.5 3.1 9.2 0.0 0.5 50.1 0.0 0.0 0.8 0.9 1.1 1.1 468.2 0.0 17.9 1.2 0.2 4.0 22.0 0.0 1.6 8.8 0.0 275.3 3.0 45.8 0.0 1.2 0.0 0.0 110.4 0.0 1.1 2.5 143.9 0.0 47.8 93.8 0.3 26.8 0.5 1.3 0.1 0.0 1.9 109.1 1.3 0.0 0.5 7.3 1.2 0.0 6.9 15.8 0.1 0.5 1.6 0.0 0.8 21.2 4.3 0.1 1.0 PELP1 MNAR ENSG00000141456 "Proline, glutamate and leucine rich protein 1" Q8IZL8 17 4669774-4704337 "Predicted intracellular proteins" Transcription "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053966, HPA056028, HPA060760" Supported Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nucleoli" "HPA053966: AB_2682325, HPA056028: AB_2683013, HPA060760: AB_2684355" "unprognostic (8.81e-2)" "unprognostic (1.22e-2)" "unprognostic (2.81e-3)" "unprognostic (2.24e-1)" "unprognostic (1.39e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (6.44e-4)" "unprognostic (2.72e-1)" "unprognostic (2.76e-1)" "unprognostic (4.31e-2)" "prognostic favorable (4.07e-5)" "unprognostic (2.20e-2)" "unprognostic (4.05e-2)" "unprognostic (1.31e-2)" "unprognostic (3.31e-1)" "unprognostic (8.32e-2)" "unprognostic (5.15e-2)" 14.2 17.8 34.9 13.4 34.1 10.9 14.9 29.9 33.1 19.9 21.2 18.3 11.8 21.5 6.2 19.5 19.8 8.8 23.1 33.4 30.7 16.8 17.7 13.1 16.3 34.2 33.3 21.9 17.5 15.5 23.5 11.4 33.8 20.5 7.5 8.7 15.3 12.2 46.8 18.7 17.4 10.8 31.8 20.5 17.5 32.8 33.6 12.5 17.2 18.1 12.0 19.5 17.0 33.9 41.8 89.8 34.8 55.3 26.5 19.5 77.9 29.6 20.5 40.1 42.7 88.1 30.0 100.0 44.4 23.4 28.5 62.6 65.1 46.3 22.6 52.1 93.2 44.6 45.1 72.0 34.2 36.4 57.5 23.9 28.2 49.5 41.3 20.7 30.2 52.9 54.7 42.6 22.4 57.2 68.9 42.7 57.3 40.2 29.7 71.7 30.8 49.3 28.2 31.2 34.8 46.5 50.8 36.9 39.4 33.1 44.6 24.3 30.7 30.9 43.5 47.3 57.9 22.7 42.5 41.6 34.9 37.1 40.6 0.2 0.7 2.0 0.9 1.0 0.9 0.8 0.9 0.7 0.8 1.3 0.9 1.3 0.2 1.3 1.2 1.1 0.6 0.7 34.9 34.1 29.9 33.1 33.4 30.7 34.2 33.3 33.8 31.8 33.6 33.9 10.4 22.4 30.1 11.1 18.5 14.8 14.8 15.7 21.1 24.0 13.5 12.4 22.6 8.6 20.9 9.2 16.7 30.9 15.3 11.8 1.9 15.9 64.7 16.6 17.3 13.7 12.6 14.1 10.6 14.6 28.3 16.6 16.8 17.6 30.9 21.1 5.0 10.6 16.9 35.3 13.0 18.6 12.2 6.0 20.4 27.0 9.3 10.4 10.6 5.6 65.1 10.7 5.2 5.0 11.5 11.4 11.7 19.2 23.6 19.3 8.3 4.7 22.3 17.8 6.6 16.8 14.8 31.3 67.5 20.0 16.3 21.2 17.4 16.6 21.9 13.0 PENK ENSG00000181195 Proenkephalin P01210 8 56436674-56446671 "Plasma proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 376.2;brain: 164.1;testis: 129.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 758.4;Leydig cells: 1137.9;Peritubular cells: 225.7;Spermatocytes: 274.1" "Cancer enhanced" "Detected in many" "lung cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 14.3;ASC TERT1: 8.6;BJ: 7.7;THP-1: 7.7" "Region enriched" "Detected in all" 7 "basal ganglia: 3626.9" "Region enriched" "Detected in all" 7 "basal ganglia: 923.2" "HPA013138, CAB016390" Enhanced "Secreted in other tissues" NA NA 220000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB016390: AB_2161515, HPA013138: AB_1855191" "unprognostic (6.89e-2)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" "unprognostic (1.17e-3)" "unprognostic (1.56e-2)" "unprognostic (3.58e-3)" "unprognostic (1.31e-2)" "unprognostic (3.60e-1)" "unprognostic (6.34e-2)" "unprognostic (5.73e-2)" "unprognostic (3.47e-2)" "unprognostic (4.24e-2)" "unprognostic (1.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (3.98e-3)" 8.6 376.2 29.9 4.4 164.1 0.0 4.9 45.2 45.6 9.2 0.5 23.1 1.1 8.1 0.0 1.4 7.6 12.5 25.6 2.7 74.0 0.2 0.2 3.7 0.1 81.4 15.9 29.7 1.1 0.0 17.1 2.9 51.3 22.4 2.0 0.6 2.7 23.4 3.0 0.8 4.2 4.6 54.0 0.1 10.0 129.0 38.0 0.2 1.0 5.3 0.1 0.6 6.2 10.1 0.0 0.0 0.1 0.0 14.3 8.6 0.0 7.7 2.5 1.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 29.9 164.1 45.2 45.6 2.7 74.0 81.4 15.9 51.3 54.0 38.0 10.1 0.2 0.0 1.5 0.3 0.5 0.1 0.2 758.4 0.0 0.3 0.1 0.6 0.8 0.0 8.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 85.7 0.1 3.1 0.9 0.0 0.0 0.4 0.0 0.1 16.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.4 0.0 2.0 0.0 0.7 60.8 1137.9 1.2 0.0 1.9 0.0 0.0 0.0 0.5 0.4 0.0 0.0 225.7 0.0 0.2 0.0 0.0 3.6 0.0 6.6 1.7 1.2 274.1 19.1 0.1 0.4 0.0 0.2 3.1 0.0 0.0 PET100 C19orf79 ENSG00000229833 "PET100 cytochrome c oxidase chaperone" P0DJ07 19 7629793-7631956 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067288 Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA067288: AB_2732762" "unprognostic (7.02e-2)" "prognostic favorable (6.81e-4)" "unprognostic (1.57e-1)" "unprognostic (9.87e-3)" "unprognostic (2.14e-1)" "unprognostic (4.18e-2)" "unprognostic (1.70e-1)" "prognostic favorable (7.97e-4)" "unprognostic (4.89e-1)" "unprognostic (2.88e-3)" "unprognostic (2.49e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (2.66e-2)" "prognostic favorable (2.44e-4)" 35.0 45.6 77.8 38.3 76.8 85.2 38.8 77.3 125.7 28.0 81.7 39.5 38.1 25.1 46.1 40.3 23.4 6.6 70.0 77.0 77.2 49.7 65.5 28.4 26.6 76.8 78.1 23.0 33.1 75.9 41.5 23.0 77.3 29.9 28.1 64.8 43.3 22.8 79.3 31.3 33.0 17.0 75.5 36.5 45.8 31.1 76.7 75.9 34.7 65.1 31.9 27.3 29.5 79.0 72.2 63.5 112.2 67.9 54.9 39.3 40.7 60.0 34.6 40.9 39.7 60.6 47.3 48.3 102.8 46.3 49.8 61.9 52.3 55.4 34.1 110.5 108.0 69.1 136.8 96.5 27.4 118.8 62.2 44.4 35.4 27.6 28.6 64.5 59.2 113.5 50.5 179.4 43.2 80.7 128.1 182.0 73.0 83.2 141.0 77.0 64.4 113.6 85.8 86.8 63.3 74.3 79.4 71.5 68.3 69.6 51.9 153.2 63.6 31.8 39.1 64.4 90.1 157.5 134.0 86.0 58.1 89.3 38.7 806.4 481.1 576.6 241.3 408.1 227.5 338.5 276.8 256.6 309.2 332.5 256.1 268.1 468.2 227.4 370.5 538.5 390.0 501.2 77.8 76.8 77.3 125.7 77.0 77.2 76.8 78.1 77.3 75.5 76.7 79.0 109.5 150.6 189.0 6.2 137.2 50.2 39.8 194.1 87.6 52.7 136.8 109.6 54.1 197.3 150.6 259.3 22.9 126.7 159.3 275.4 215.2 215.7 51.1 156.7 101.9 93.3 191.5 238.4 4.5 318.3 128.9 82.6 144.3 160.7 106.9 69.0 171.0 542.3 171.7 18.5 4.5 255.4 158.7 236.4 103.8 47.3 101.5 161.2 113.8 10.3 228.8 123.0 130.7 4.5 8.4 351.4 302.4 83.1 198.9 57.0 341.9 295.9 160.2 96.5 85.5 52.0 80.4 126.5 84.0 127.0 59.1 178.8 131.0 30.1 213.1 53.0 PET117 CSRP2BP ENSG00000232838 "PET117 cytochrome c oxidase chaperone" Q6UWS5 20 18137863-18143169 "Disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" HPA047716 Approved "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA047716: AB_2680128" "unprognostic (1.34e-2)" "unprognostic (2.83e-1)" "unprognostic (3.94e-1)" "unprognostic (2.02e-1)" "unprognostic (2.39e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (4.76e-6)" "unprognostic (7.74e-2)" "unprognostic (1.25e-1)" "unprognostic (3.13e-2)" "unprognostic (4.90e-1)" "unprognostic (2.78e-1)" "prognostic favorable (4.15e-4)" "unprognostic (3.73e-1)" "unprognostic (4.63e-1)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" 8.7 16.8 12.5 5.5 13.0 8.0 8.5 12.8 17.8 8.4 13.5 12.2 15.6 9.9 10.4 8.0 8.5 5.1 12.9 12.6 12.9 14.1 12.5 8.0 6.0 12.7 12.4 10.0 11.4 9.7 11.8 7.4 13.0 9.3 9.4 9.7 10.4 6.5 22.9 10.8 10.9 5.8 12.8 8.6 16.5 7.2 12.8 4.5 8.9 9.6 5.3 9.5 7.6 13.8 33.0 28.7 10.4 10.6 14.9 11.3 29.8 16.8 16.5 19.6 18.2 26.5 26.7 19.5 27.0 16.1 34.9 17.6 19.0 31.5 20.5 4.4 20.9 21.9 19.2 63.8 24.6 29.2 23.2 17.8 17.1 19.3 20.1 15.7 15.7 23.3 18.6 17.1 14.3 26.8 17.1 33.5 15.4 35.2 31.8 15.3 33.4 35.0 21.2 19.4 18.9 18.6 23.1 43.0 46.9 27.1 26.2 21.3 15.0 17.7 13.7 19.0 29.4 24.4 41.8 31.5 8.8 9.5 16.3 3.4 24.9 11.4 18.3 23.3 20.7 26.2 22.7 23.0 22.0 23.2 31.6 24.2 1.5 21.0 29.7 41.0 20.4 15.8 12.5 13.0 12.8 17.8 12.6 12.9 12.7 12.4 13.0 12.8 12.8 13.8 10.3 19.2 10.6 0.3 11.4 3.8 16.7 17.2 8.0 16.9 13.5 14.6 13.7 35.8 16.3 16.5 4.2 29.8 12.4 15.4 33.2 21.8 1.0 12.3 8.8 9.1 15.7 16.8 2.6 26.7 34.5 10.1 24.5 11.9 8.8 6.9 8.9 25.8 14.9 23.5 2.5 18.4 16.2 13.9 4.0 3.2 16.1 7.7 7.2 1.9 15.1 19.7 16.5 3.5 1.4 34.0 12.3 6.8 9.4 26.8 44.0 53.1 9.4 13.7 6.6 9.6 10.8 16.3 31.3 13.4 6.3 13.0 11.9 9.7 23.6 14.5 PEX6 "PAF-2, PXAAA1" ENSG00000124587 "Peroxisomal biogenesis factor 6" Q13608 6 42963865-42979181 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis" "Amelogenesis imperfecta, Deafness, Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 76.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 78.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025924, HPA074179" Supported Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA025924: AB_1855230, HPA074179: " "unprognostic (7.32e-3)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (9.16e-2)" "unprognostic (9.18e-2)" "unprognostic (3.27e-1)" "unprognostic (8.88e-2)" "unprognostic (5.92e-2)" "unprognostic (3.36e-1)" "unprognostic (7.12e-2)" "unprognostic (7.24e-3)" "unprognostic (5.31e-2)" "unprognostic (3.79e-3)" "unprognostic (1.86e-1)" "unprognostic (1.13e-1)" "unprognostic (1.81e-1)" "unprognostic (1.55e-1)" 11.6 20.5 24.9 9.2 25.2 9.5 12.1 23.9 27.7 19.1 25.5 16.3 9.3 15.5 7.7 16.4 22.7 9.6 18.7 25.1 25.5 16.5 27.7 10.0 14.5 27.2 25.5 26.1 76.2 15.2 24.3 9.6 24.2 21.6 7.8 9.9 14.8 11.4 23.4 14.0 16.3 9.6 23.9 17.5 16.3 16.2 25.1 14.7 19.8 15.0 10.4 17.3 15.7 25.2 35.0 16.4 8.1 30.6 29.6 28.3 8.4 6.0 9.4 4.8 10.0 10.5 10.1 14.1 8.2 14.3 20.5 32.2 28.7 31.1 5.0 27.6 15.2 4.7 24.4 6.2 20.0 4.8 9.4 35.5 35.5 19.9 5.5 39.1 24.7 18.9 25.2 14.1 10.7 3.9 12.7 15.8 10.0 78.8 14.3 26.8 14.3 5.8 12.3 10.0 25.4 11.1 5.6 21.9 32.7 13.1 43.2 21.2 14.0 15.2 2.9 7.5 14.0 21.0 19.8 19.7 5.2 24.6 12.4 1.3 1.3 2.1 1.2 1.1 2.1 1.0 1.8 2.5 1.9 1.9 2.2 2.1 0.8 2.0 0.7 1.0 0.9 1.1 24.9 25.2 23.9 27.7 25.1 25.5 27.2 25.5 24.2 23.9 25.1 25.2 5.6 6.4 2.6 19.9 5.6 5.0 10.2 6.2 10.8 15.2 11.8 12.7 4.1 10.0 5.6 7.3 2.1 11.4 5.4 10.2 13.7 2.8 2.5 17.6 10.6 5.8 5.4 1.7 24.6 1.5 6.7 9.2 11.2 9.1 0.0 19.8 8.6 14.1 5.8 21.9 22.4 8.5 6.1 9.7 3.2 3.6 14.6 5.4 8.8 9.4 4.5 11.8 9.2 13.0 16.6 1.9 10.4 9.4 3.1 6.3 15.1 13.9 14.3 7.0 0.0 13.0 6.6 7.3 2.6 6.3 5.5 7.4 7.8 26.1 10.5 6.6 PF4 "CXCL4, SCYB4" ENSG00000163737 "Platelet factor 4" P02776 4 73980811-73982027 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 66.5;lymphoid tissue: 31.5" "Cell type enriched" "Detected in some" 23 "Macrophages: 1360.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.4" "Region enriched" "Detected in single" 5 "cerebral cortex: 2.2" "Group enriched" "Detected in many" 12 "basophil: 85.2;neutrophil: 43.0" "Lineage enriched" "Detected in many" 16 "granulocytes: 85.2" "Cell line enriched" "Detected in some" 10 "HEL: 29.8" "CAB026008, HPA052485" Enhanced "Secreted to blood" NA NA 7700000 "Cluster 34: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "CAB026008: , HPA052485: AB_2681847" "unprognostic (4.14e-4)" "unprognostic (1.00e-2)" "unprognostic (2.49e-1)" "unprognostic (1.96e-4)" "unprognostic (7.58e-2)" "unprognostic (1.42e-1)" "unprognostic (7.55e-2)" "unprognostic (2.04e-1)" "unprognostic (9.02e-3)" "unprognostic (1.84e-2)" "unprognostic (3.03e-2)" "unprognostic (9.54e-5)" "unprognostic (2.55e-1)" "unprognostic (8.77e-2)" "unprognostic (9.69e-2)" "unprognostic (4.81e-2)" 0.8 0.2 0.1 0.7 0.3 66.5 0.3 0.1 2.2 0.1 0.7 1.0 0.0 0.1 0.0 0.1 0.3 0.7 0.9 0.1 0.1 0.6 2.2 10.5 0.3 0.3 0.2 0.1 0.3 0.0 0.3 3.0 0.3 0.1 0.8 0.0 0.4 0.1 1.0 0.0 0.2 0.1 0.4 31.5 0.9 0.1 0.2 0.0 0.6 2.5 0.0 0.1 0.1 0.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 29.8 0.0 0.0 1.5 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.2 3.8 1.4 0.8 1.2 0.8 0.0 0.2 0.0 1.5 0.7 0.7 0.3 43.0 0.1 3.9 5.4 0.6 148.4 0.1 0.3 0.1 2.2 0.1 0.1 0.3 0.2 0.3 0.4 0.2 0.3 0.7 0.0 0.0 0.0 10.8 0.0 0.2 0.4 0.0 0.0 0.1 0.3 0.0 2.8 1.5 1.8 0.0 0.0 4.1 5.3 0.0 6.0 0.0 0.0 0.0 7.1 13.3 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.0 0.0 24.7 0.2 0.3 0.0 0.0 1.8 0.0 9.5 0.0 0.1 0.0 1360.7 0.0 0.0 59.0 0.0 57.7 0.0 0.0 7.6 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 0.4 0.0 0.0 0.3 5.8 0.0 7.4 0.2 PF4V1 "CXCL4L1, CXCL4V1, SCYB4V1" ENSG00000109272 "Platelet factor 4 variant 1" P10720 4 73853296-73854483 "Plasma proteins, Predicted secreted proteins" "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.7;lymphoid tissue: 2.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 10.0;Club cells: 2.6;Enteroendocrine cells: 5.3;Macrophages: 6.4;Theca cells: 2.2" "Cancer enhanced" "Detected in some" "renal cancer: 3.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 38 "basophil: 14.2;neutrophil: 9.9" "Lineage enriched" "Detected in single" 45 "granulocytes: 14.2" "Cell line enhanced" "Detected in single" "EFO-21: 1.7" HPA052485 Supported "Secreted to blood" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA052485: AB_2681847" "unprognostic (4.95e-1)" "unprognostic (5.68e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-3)" "unprognostic (9.88e-2)" "unprognostic (1.72e-2)" "unprognostic (1.68e-3)" "unprognostic (2.66e-1)" "unprognostic (6.02e-2)" "unprognostic (2.65e-1)" "unprognostic (1.95e-3)" "unprognostic (1.39e-2)" "unprognostic (2.11e-1)" 0.2 0.0 0.0 0.1 0.2 1.2 0.2 0.0 0.3 0.2 0.1 0.1 1.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.7 0.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.4 1.1 0.0 0.0 0.9 0.0 0.0 2.4 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 9.9 0.0 0.1 0.3 0.0 11.2 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.2 0.1 0.0 10.0 2.6 1.8 0.0 0.0 0.0 0.1 1.9 0.3 0.0 0.2 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.7 2.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 6.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 1.4 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.5 PFAS "FGARAT, GATD8, KIAA0361, PURL" ENSG00000178921 "Phosphoribosylformylglycinamidine synthase" O15067 17 8247618-8270491 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 49.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022140, HPA022886" Enhanced Approved Vesicles NA NA 670000 "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA022140: AB_1855232, HPA022886: AB_1855233" "unprognostic (1.90e-1)" "unprognostic (9.21e-2)" "unprognostic (2.12e-1)" "unprognostic (5.19e-3)" "unprognostic (2.59e-1)" "unprognostic (6.40e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (3.19e-1)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (5.47e-3)" "unprognostic (1.08e-3)" "unprognostic (9.51e-3)" "unprognostic (3.63e-2)" "unprognostic (6.57e-2)" "unprognostic (2.88e-3)" "unprognostic (3.85e-1)" 8.4 9.9 4.7 7.8 5.1 9.8 8.2 6.2 5.8 7.8 2.8 6.7 4.8 9.0 2.6 8.4 8.0 2.8 6.3 5.1 3.3 11.0 10.1 5.8 9.8 3.9 3.9 9.7 10.3 5.6 5.5 5.2 4.6 6.9 5.6 5.8 6.4 4.7 6.4 6.8 7.7 6.8 3.3 11.0 7.8 7.8 3.9 7.5 7.8 3.2 8.2 7.6 6.2 6.0 15.6 67.0 33.8 50.2 12.1 10.0 38.7 19.4 7.4 35.1 26.4 32.9 13.7 69.8 30.8 11.4 12.4 35.1 78.5 25.6 25.8 30.6 64.0 40.0 63.2 41.9 10.4 32.9 28.3 9.5 6.2 40.5 25.5 9.9 29.5 36.6 54.8 10.1 13.7 23.0 58.1 28.4 55.7 8.5 29.9 86.0 35.2 32.6 16.1 25.5 20.4 31.7 24.1 15.3 22.2 17.9 15.3 14.9 20.9 19.2 25.0 35.7 49.0 11.8 23.5 33.7 21.0 45.4 32.9 20.2 5.1 12.7 6.8 4.5 8.7 14.8 8.8 7.9 4.4 16.7 10.9 8.6 49.1 5.2 3.7 12.9 5.0 2.3 4.7 5.1 6.2 5.8 5.1 3.3 3.9 3.9 4.6 3.3 3.9 6.0 2.9 0.0 7.9 3.9 6.0 2.4 1.7 1.9 1.8 8.1 4.5 3.7 4.3 1.5 4.1 3.7 6.2 5.2 3.2 2.1 0.0 3.7 2.1 2.4 5.9 3.6 0.0 9.2 5.8 3.0 4.3 4.0 5.6 3.7 1.3 9.7 2.5 4.2 4.6 1.7 5.4 3.5 2.0 2.5 1.4 1.1 5.3 3.4 3.6 4.7 4.5 1.6 4.1 6.6 3.9 1.9 4.9 1.5 5.3 2.9 0.8 2.7 5.1 7.3 0.0 5.1 3.2 5.6 8.8 3.9 2.0 3.1 3.3 7.7 6.2 1.4 PFDN5 "MM-1, PFD5" ENSG00000123349 "Prefoldin subunit 5" Q99471 12 53295291-53299452 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 3559.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA008587 Approved Supported "Intermediate filaments,Cytosol" NA NA 110000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 32: Non-specific - Translation" "Intermediate filaments, Cytosol" "HPA008587: AB_1079597" "unprognostic (3.56e-3)" "unprognostic (2.31e-2)" "unprognostic (2.87e-2)" "unprognostic (4.02e-3)" "unprognostic (1.59e-1)" "unprognostic (3.44e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-2)" "unprognostic (2.65e-2)" "unprognostic (2.12e-1)" "prognostic favorable (5.45e-4)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.34e-2)" "unprognostic (9.48e-2)" "unprognostic (2.30e-2)" "unprognostic (2.01e-3)" 719.5 656.4 903.9 307.4 919.3 863.9 819.2 894.2 1279.0 907.5 890.8 684.3 238.6 555.3 867.4 520.1 654.0 366.1 633.1 880.3 907.3 677.4 505.6 539.2 610.5 907.4 899.1 1007.6 724.5 606.1 688.1 399.6 910.7 671.6 371.8 371.8 557.5 394.2 723.2 684.8 514.0 357.2 935.9 712.7 591.9 388.0 927.2 547.7 634.5 615.5 625.9 614.7 651.4 928.1 333.3 492.3 472.8 426.6 889.1 1220.7 347.2 814.5 1081.9 730.8 489.3 456.0 496.9 449.2 479.3 871.1 285.7 299.0 416.7 575.0 702.6 425.4 575.7 410.6 639.1 634.6 574.3 676.8 425.6 1174.9 823.4 522.7 398.6 1269.3 658.4 539.4 485.7 589.1 735.3 1150.9 478.1 993.0 447.7 359.1 757.4 381.1 514.6 530.8 842.9 477.8 396.5 454.1 525.6 450.1 612.1 481.8 588.1 843.6 585.6 408.2 319.1 198.7 372.6 444.5 500.8 670.7 450.3 528.5 386.0 1641.6 2761.6 989.6 1636.2 2095.6 2283.3 3705.2 2468.1 2003.4 2060.9 3368.6 3147.1 2533.0 740.8 1645.0 2221.2 1921.0 2149.1 8653.7 903.9 919.3 894.2 1279.0 880.3 907.3 907.4 899.1 910.7 935.9 927.2 928.1 711.6 262.8 501.5 27.7 1274.1 1505.2 1217.7 1648.8 900.3 184.0 1219.6 1850.4 598.0 684.9 778.6 566.4 102.2 899.8 862.2 593.0 1412.6 561.2 902.9 629.9 703.6 734.7 659.9 587.9 25.3 961.0 973.4 708.4 362.9 440.2 655.9 647.4 782.8 584.8 1830.1 72.3 25.0 892.0 734.5 1977.7 2549.4 3559.9 948.7 1235.9 1538.5 15.9 1663.4 619.2 905.3 21.6 27.6 705.6 990.6 655.2 582.9 971.9 1053.0 2024.3 862.7 321.5 552.2 713.6 902.4 469.7 234.3 762.4 1526.5 876.0 1147.0 658.2 849.4 1114.8 PFN1 ENSG00000108518 "Profilin 1" P07737 17 4945652-4949061 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 5241.0;monocytes: 4824.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037134, CAB037140" Enhanced Approved Cytosol NA NA 660000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB037134: AB_1079599, CAB037140: AB_1079598" "unprognostic (1.07e-1)" "unprognostic (3.57e-1)" "unprognostic (1.60e-1)" "unprognostic (5.45e-3)" "unprognostic (1.65e-1)" "unprognostic (7.54e-2)" "unprognostic (4.01e-3)" "unprognostic (7.83e-3)" "unprognostic (3.38e-1)" "unprognostic (1.09e-3)" "unprognostic (2.17e-1)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (3.62e-1)" "unprognostic (8.17e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" 573.1 365.8 278.0 1133.4 302.0 1613.0 397.0 323.2 333.0 393.7 289.2 970.2 764.0 734.4 346.4 582.7 500.9 372.7 343.8 281.8 301.5 460.9 661.6 559.2 1357.9 347.3 325.4 247.7 246.4 311.3 198.9 581.1 348.6 419.4 808.4 71.8 346.9 601.4 337.9 449.8 772.9 1034.7 315.2 910.8 675.1 116.2 366.2 1197.6 269.2 238.7 1440.0 842.6 425.0 355.2 3019.5 4276.8 1461.5 1205.2 778.8 977.1 1972.7 2416.8 1970.4 2568.6 1923.7 1684.1 1181.1 2476.9 1892.0 2542.0 1453.6 1825.4 1383.6 3040.5 2049.6 3560.1 2355.1 2516.6 2034.3 2225.8 2144.0 1630.4 5006.0 1152.4 1331.9 1957.6 1939.8 1477.6 2361.3 1646.4 1488.6 1736.7 3150.5 1815.0 2469.9 3448.0 2095.2 1474.7 2297.3 2451.9 2035.1 1494.6 2491.7 1909.8 564.0 1586.2 1910.5 1180.9 1679.7 1226.8 1121.0 1359.7 2731.7 2136.6 1675.1 1512.3 3969.3 931.3 1070.7 1799.3 1834.4 1949.7 3316.4 8100.1 8206.3 13914.4 9850.0 10858.8 6780.3 5722.0 8185.7 9586.6 9920.0 4970.0 5238.0 7604.7 9387.0 9112.1 13547.4 7809.7 11245.6 23570.1 278.0 302.0 323.2 333.0 281.8 301.5 347.3 325.4 348.6 315.2 366.2 355.2 561.8 112.2 176.1 12.1 1070.6 1806.0 873.2 3658.3 1003.3 25.0 767.4 914.1 147.6 457.5 1020.0 741.2 0.0 1911.0 1725.6 1733.8 992.0 1866.6 19.7 313.4 546.1 806.6 603.7 713.5 7.1 1625.2 5241.0 599.9 733.4 422.7 486.5 291.2 637.5 754.3 4094.2 38.7 6.4 1399.7 1452.6 1434.3 2934.8 31.0 263.8 1854.7 873.4 21.5 4824.7 99.8 3216.3 9.0 37.2 2933.5 1585.7 375.0 927.8 1238.2 1472.2 1671.2 559.4 17.8 506.2 282.3 1838.4 97.4 355.4 1170.1 1513.5 1682.8 1804.7 410.7 1355.5 1177.9 PGA3 ENSG00000229859 "Pepsinogen A3" P0DJD8 11 61203307-61213098 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 613 "stomach 1: 89073.4" "Cell type enriched" "Detected in some" 526 "Gastric mucus-secreting cells: 3263.5" "Cancer enriched" "Detected in single" 498 "stomach cancer: 24.8" "Region enhanced" "Detected in single" "hippocampal formation: 2.9" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HMC-1: 2.8;THP-1: 1.1" "CAB026358, HPA046875" Enhanced "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB026358: , HPA046875: AB_2679851" "unprognostic (6.39e-2)" "unprognostic (1.11e-1)" 80.5 10.0 0.5 0.2 0.2 0.2 18.2 0.7 0.9 11.1 0.0 145.3 1.3 3.8 0.0 96.4 4.5 0.1 11.4 2.9 0.0 5.4 16.2 6.2 0.0 0.0 0.0 5.4 13.0 0.0 13.4 0.5 0.1 5.5 0.1 0.9 6.8 0.7 4.4 6.0 5.7 0.4 0.0 6.3 89073.4 7.3 0.0 0.1 5.0 0.5 0.1 6.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.1 0.7 1.3 0.4 0.1 0.2 0.7 0.1 0.1 0.1 0.6 0.4 0.2 0.3 0.0 0.0 1.3 0.5 0.2 0.7 0.9 2.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 6.2 0.0 0.3 3263.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.1 0.0 3.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.1 PGA4 ENSG00000229183 "Pepsinogen A4" P0DJD7 11 61222349-61231694 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1281 "stomach 1: 66596.4" "Cell type enriched" "Detected in some" 8 "Exocrine glandular cells: 109.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "classical monocyte: 9.9;intermediate monocyte: 10.9;non-classical monocyte: 3.4" "Lineage enriched" "Detected in single" 26 "monocytes: 10.9" "Group enriched" "Detected in some" 6 "BJ hTERT+: 26.1;HMC-1: 9.5;THP-1: 15.7" HPA046875 Supported "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 1: Pancreatic cells - Digestion" "HPA046875: AB_2679851" "unprognostic (2.22e-1)" 9.6 8.3 0.1 2.1 0.1 0.0 9.0 0.1 0.2 7.5 0.1 52.0 2.5 4.6 0.0 9.1 19.1 0.3 6.2 0.1 0.1 30.3 11.7 37.9 0.0 0.1 0.1 4.1 18.8 0.0 3.5 3.8 0.1 16.2 0.4 0.3 4.5 0.7 2.5 4.1 2.9 0.8 0.1 5.2 66596.4 4.3 0.1 0.1 3.1 0.0 0.2 5.0 5.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.0 0.0 1.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 1.1 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.3 0.0 3.4 0.0 0.0 1.8 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 109.1 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGA5 ENSG00000256713 "Pepsinogen A5" P0DJD9 11 61241175-61251444 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2014 "stomach 1: 39870.8" "Cell type enriched" "Detected in some" 77 "Exocrine glandular cells: 4383.1" "Cancer enriched" "Detected in some" 12 "stomach cancer: 15.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 29 "classical monocyte: 1.8;intermediate monocyte: 4.3;non-classical monocyte: 2.4" "Lineage enriched" "Detected in single" 44 "monocytes: 4.3" "Cell line enriched" "Detected in some" 19 "BJ hTERT+: 28.8" HPA046875 Supported "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "HPA046875: AB_2679851" "unprognostic (1.36e-3)" "unprognostic (2.98e-2)" "unprognostic (5.83e-3)" "unprognostic (2.11e-1)" "unprognostic (4.22e-1)" "unprognostic (4.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "unprognostic (7.10e-2)" 19.7 4.4 0.3 1.1 0.3 0.0 4.5 0.1 0.6 4.0 0.0 6.2 0.6 1.9 0.0 7.0 5.1 0.1 3.5 0.7 0.0 2.4 7.0 5.4 0.0 0.1 0.0 2.6 8.2 0.0 3.8 0.5 0.1 1.8 0.1 1.5 2.5 0.5 1.9 2.1 2.1 0.9 0.0 3.9 39870.8 2.3 0.0 0.2 3.1 0.2 0.1 2.3 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.3 0.3 0.3 0.1 0.6 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 4383.1 0.0 0.1 56.6 0.0 0.0 0.2 0.0 0.0 6.7 0.0 0.0 0.0 0.0 5.1 0.0 1.6 0.9 1.3 0.0 0.0 1.0 25.1 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PGAM5 "BXLBv68, MGC5352" ENSG00000247077 "PGAM family member 5, mitochondrial serine/threonine protein phosphatase" Q96HS1 12 132710819-132722734 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Necrosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036978, HPA036979, CAB068215" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB068215: AB_2665674, HPA036978: AB_10964347, HPA036979: AB_10960559" "unprognostic (9.57e-2)" "unprognostic (2.00e-2)" "unprognostic (3.83e-2)" "unprognostic (3.11e-2)" "unprognostic (3.46e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.13e-6)" "unprognostic (3.32e-2)" "unprognostic (1.47e-1)" "unprognostic (5.67e-2)" "unprognostic (1.23e-1)" "unprognostic (6.92e-2)" "unprognostic (6.42e-3)" "unprognostic (1.63e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (5.53e-2)" 10.5 17.7 13.0 17.0 12.7 16.3 9.7 12.7 17.0 9.8 10.1 16.1 15.2 10.9 6.6 23.9 12.4 8.7 20.0 19.0 12.5 14.3 28.9 9.3 21.2 9.3 9.7 7.2 25.8 10.7 9.9 10.7 10.1 9.4 11.3 6.0 15.5 11.5 33.2 17.1 13.2 11.3 7.9 12.8 13.3 16.5 10.8 14.8 11.6 19.0 16.1 15.6 11.8 11.3 72.2 134.3 28.2 79.5 19.4 15.6 66.1 37.4 22.0 59.1 33.0 168.6 40.2 92.3 67.2 31.2 30.4 61.2 132.9 67.5 24.1 47.3 106.7 110.7 61.6 89.2 44.0 105.8 61.8 19.4 48.8 69.0 73.6 19.3 43.6 73.4 143.3 36.9 23.5 128.5 144.5 105.7 108.0 61.8 94.4 109.4 31.2 73.3 38.4 97.4 102.8 58.0 62.2 86.1 38.9 22.2 108.9 57.5 38.2 29.9 65.5 60.6 89.9 77.2 124.8 133.5 38.8 85.3 51.1 4.9 1.1 0.3 1.1 1.2 1.8 1.7 1.3 1.3 1.0 1.7 1.3 1.7 0.9 1.6 1.7 3.3 1.1 0.8 13.0 12.7 12.7 17.0 19.0 12.5 9.3 9.7 10.1 7.9 10.8 11.3 6.6 3.2 6.1 3.9 8.9 11.5 16.7 2.6 2.2 9.5 7.8 5.5 15.1 15.7 1.5 5.5 14.6 7.6 11.9 11.7 5.9 5.8 14.5 6.3 6.3 7.0 13.1 5.0 5.1 7.9 14.4 4.9 4.1 9.3 0.0 7.1 5.7 22.4 7.3 6.7 3.9 8.9 2.0 6.9 5.8 20.6 5.9 4.7 3.6 1.9 5.3 4.4 3.1 2.0 2.3 7.5 6.9 6.8 9.7 19.5 5.2 11.5 4.5 12.9 6.6 8.0 6.4 15.1 10.1 10.8 17.3 6.2 7.4 9.2 15.7 16.1 PGAP3 "CAB2, MGC9753, PER1, PERLD1, PP1498" ENSG00000161395 "Post-GPI attachment to proteins phospholipase 3" Q96FM1 17 39671122-39696797 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "OE19: 800.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016591 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA016591: AB_1855203" "unprognostic (1.29e-1)" "unprognostic (8.64e-2)" "unprognostic (1.65e-1)" "unprognostic (6.53e-3)" "unprognostic (9.19e-2)" "unprognostic (1.68e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.61e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.57e-2)" "unprognostic (7.79e-2)" "prognostic favorable (3.89e-4)" "unprognostic (5.16e-2)" "unprognostic (1.31e-1)" "unprognostic (9.05e-2)" "unprognostic (1.94e-2)" 10.5 11.9 17.0 5.6 17.2 5.0 12.9 14.0 19.6 14.6 16.2 18.6 14.9 11.3 18.3 25.8 15.9 13.4 14.8 17.5 16.7 20.6 35.6 12.1 7.4 14.9 15.4 13.5 27.1 22.7 14.9 11.8 14.6 18.5 13.7 7.1 25.1 11.7 8.3 21.0 17.1 6.1 14.7 12.3 16.6 9.1 16.5 4.8 27.1 4.5 7.5 12.2 13.7 15.5 3.7 9.6 7.7 7.0 7.9 8.1 7.9 4.3 10.1 6.7 6.1 5.4 23.8 4.2 19.7 8.3 2.2 12.6 2.4 2.9 3.1 8.6 7.7 5.2 6.0 9.3 10.6 12.9 12.8 14.9 15.0 3.1 6.8 7.6 2.2 1.9 4.9 9.6 6.1 8.7 2.9 11.7 7.6 800.4 2.1 3.2 4.7 12.1 10.7 12.0 7.1 4.7 11.9 134.0 6.9 0.8 11.4 12.4 3.4 7.2 7.6 3.5 3.3 8.5 2.0 1.4 8.1 4.9 8.1 2.6 7.2 4.6 15.2 11.6 8.3 8.1 10.6 12.5 5.7 7.7 10.1 10.1 2.0 10.4 4.3 3.9 5.4 7.3 17.0 17.2 14.0 19.6 17.5 16.7 14.9 15.4 14.6 14.7 16.5 15.5 6.5 3.2 14.9 7.8 3.7 3.8 3.3 5.6 3.4 12.6 9.1 7.0 7.7 14.3 10.1 14.7 8.4 8.1 5.3 20.3 1.9 7.6 0.1 3.5 4.5 5.0 8.4 3.0 9.0 11.1 6.5 5.1 9.2 5.7 8.9 6.8 4.6 9.0 4.4 13.5 6.3 15.3 8.2 5.1 2.8 0.1 3.1 3.7 1.8 2.8 1.9 7.5 4.1 9.0 6.1 6.3 13.9 1.5 2.8 3.7 22.9 3.4 4.9 22.1 0.0 5.0 3.3 0.7 2.4 8.1 2.8 10.4 4.9 5.8 13.3 3.1 PGC ENSG00000096088 Progastricsin P20142 6 41736711-41754109 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Digestion "Aspartyl protease, Hydrolase, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "stomach 1: 59821.1" "Group enriched" "Detected in some" 10 "Gastric mucus-secreting cells: 5737.5;Pancreatic endocrine cells: 1449.1" "Cancer enhanced" "Detected in many" "stomach cancer: 1050.3" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Hep G2: 253.1;OE19: 152.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031717, HPA031718" Enhanced Approved Nucleoplasm "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "HPA031717: AB_10670130, HPA031718: AB_10610148" "unprognostic (9.18e-2)" "unprognostic (1.87e-1)" "unprognostic (9.83e-2)" "unprognostic (2.27e-1)" "unprognostic (7.18e-2)" "unprognostic (2.74e-1)" "unprognostic (1.47e-1)" "unprognostic (8.50e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.33e-2)" "unprognostic (2.92e-1)" "unprognostic (1.65e-1)" "unprognostic (8.74e-2)" 19.4 7.0 0.0 0.3 0.1 0.2 6.6 1.2 0.5 6.7 0.0 26.4 1327.3 2.8 0.9 85.5 9.2 2.3 6.2 0.1 0.0 4.9 11.0 378.8 0.3 0.0 0.0 3.9 136.3 0.0 7.4 2.8 0.0 83.9 0.3 0.1 4.6 437.7 2.5 3.4 3.2 0.0 0.0 7.7 59821.1 4.2 0.0 0.1 2.2 0.0 0.3 3.8 4.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.1 0.0 0.0 18.4 0.0 0.0 0.6 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 253.1 0.0 0.3 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.9 5.7 152.2 0.0 2.9 0.0 6.2 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.3 0.0 2.8 0.0 0.0 3.7 0.1 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 25.6 335.2 0.0 4.4 0.4 2.8 0.0 0.0 0.0 0.3 0.8 0.3 87.2 5.0 0.0 0.0 1.2 0.0 0.3 0.0 4.6 0.0 0.4 0.0 1.1 0.0 0.0 0.3 131.2 1.5 0.9 5737.5 0.1 10.1 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 1.7 0.0 0.0 2.0 0.0 0.0 0.0 0.1 1449.1 2.1 0.0 2.4 85.2 0.1 0.2 3.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 4.1 2.6 0.0 0.2 4.2 PGF "D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760" ENSG00000119630 "Placental growth factor" P49763 14 74941834-74955626 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 50.5;thyroid gland: 52.5" "Group enriched" "Detected in many" 11 "Extravillous trophoblasts: 1604.4;Syncytiotrophoblasts: 2122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "BEWO: 422.4;HUVEC TERT2: 199.1" "Low region specificity" "Detected in all" HPA041624 Approved Nucleoplasm,Mitochondria,Cytosol "Secreted to blood" No No 20800 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Mitochondria, Cytosol" "HPA041624: AB_10794522" "unprognostic (1.67e-2)" "unprognostic (4.62e-2)" "unprognostic (9.25e-3)" "unprognostic (1.34e-3)" "unprognostic (8.67e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (7.26e-2)" "unprognostic (1.48e-1)" "unprognostic (4.45e-1)" "unprognostic (1.45e-2)" "unprognostic (3.51e-3)" "prognostic unfavorable (1.33e-6)" "unprognostic (2.52e-3)" "unprognostic (1.20e-1)" "unprognostic (3.49e-2)" "unprognostic (1.14e-1)" 11.8 4.9 7.4 7.8 7.6 0.1 11.3 7.3 11.7 22.4 20.2 7.0 2.4 7.6 1.4 10.0 21.8 5.9 18.8 8.7 20.6 8.1 6.0 7.2 6.4 9.5 15.7 6.4 4.9 8.4 5.5 50.5 9.3 19.3 2.0 1.2 10.5 10.3 9.9 15.7 12.5 7.8 7.0 3.3 4.8 3.2 8.6 3.9 52.5 5.9 3.3 13.6 14.8 7.8 1.4 1.5 1.3 1.3 2.0 0.2 422.4 4.0 3.6 1.8 2.2 10.9 0.6 0.3 9.1 2.8 0.2 0.5 1.8 19.2 1.6 0.2 2.4 0.0 0.1 11.3 1.5 0.2 11.0 4.7 4.5 7.5 1.8 0.5 199.1 0.0 0.0 0.1 55.6 0.9 0.0 0.5 2.1 0.1 3.4 0.2 51.3 0.0 0.5 1.0 31.0 17.0 0.0 0.8 7.7 25.0 0.1 0.5 40.6 0.3 10.2 0.1 17.0 0.4 0.2 0.7 6.3 0.5 0.5 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 7.4 7.6 7.3 11.7 8.7 20.6 9.5 15.7 9.3 7.0 8.6 7.8 32.4 9.6 4.6 1.0 1.0 24.6 10.3 111.4 34.7 1.3 8.9 16.0 3.6 0.0 26.0 0.0 14.6 83.8 2.4 2.0 0.0 2.7 0.1 1.1 3.3 169.4 7.1 2.7 0.1 0.5 1604.4 30.8 1.1 0.8 6.3 0.2 5.3 0.3 37.4 0.0 0.2 2.1 18.3 0.6 8.9 0.8 13.1 2.1 21.4 0.0 0.0 1.9 0.0 0.0 0.2 0.5 1.2 19.5 0.2 3.2 0.6 1.1 12.1 7.8 105.2 7.1 86.4 0.2 6.8 8.1 19.6 2122.6 3.0 3.0 2.3 5.8 PGLYRP1 "PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L" ENSG00000008438 "Peptidoglycan recognition protein 1" O75594 19 46019153-46023053 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 629.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Excitatory neurons: 1.7;Inhibitory neurons: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.4" "Group enriched" "Detected in some" 202 "eosinophil: 443.7;neutrophil: 494.6" "Lineage enriched" "Detected in many" 213 "granulocytes: 494.6" "Cell line enhanced" "Detected in some" "A549: 3.1;HEK 293: 1.8;HeLa: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045702, HPA070227" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 35000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "Nucleoplasm, Cytosol" "HPA045702: AB_10960204, HPA070227: " "unprognostic (2.87e-2)" "unprognostic (4.26e-1)" "unprognostic (1.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.58e-1)" "unprognostic (4.93e-3)" "unprognostic (2.20e-1)" "unprognostic (6.46e-2)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (8.51e-3)" "unprognostic (7.18e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-1)" "unprognostic (4.37e-3)" 1.5 0.3 0.3 1.8 1.1 629.4 0.3 3.4 1.5 0.1 0.0 0.3 0.6 0.2 0.0 0.5 0.6 0.2 1.7 0.6 0.0 0.8 2.5 8.7 0.5 0.0 0.1 0.1 0.5 0.0 0.7 0.9 0.0 0.2 0.0 0.0 0.5 0.0 0.3 1.0 0.7 0.1 0.0 42.5 0.4 1.0 0.0 3.3 0.5 2.3 0.0 0.4 0.2 0.0 0.3 3.1 0.5 0.3 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.5 0.2 0.8 0.1 0.0 0.2 1.2 0.0 0.0 0.0 0.8 1.8 0.3 1.7 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.3 0.3 0.0 0.2 0.2 0.9 0.2 0.0 1.2 0.7 0.1 0.0 0.0 1.2 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.7 0.6 0.3 0.4 0.7 0.0 0.2 0.4 443.7 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 494.6 0.0 2.3 0.0 0.1 3.9 0.3 1.1 3.4 1.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.2 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "liver: 258.8" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 168.7" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;monocytes: 5.1;T-cells: 2.3" "Group enriched" "Detected in some" 5 "MCF7: 8.1;T-47d: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" NA NA 87000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 6: T47d - Mammary gland" "Cluster 2: Hepatocytes - Metabolism" "Cell Junctions" "CAB033468: AB_1127187, HPA046311: AB_2679621, HPA075237: AB_2686739" "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 258.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 5.7 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 3.4 0.4 0.2 1.6 1.7 1.6 0.2 0.9 0.8 0.1 0.0 2.2 2.3 1.6 0.5 5.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.3 0.0 0.2 0.5 0.0 0.0 4.1 1.5 0.2 4.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.9 168.7 0.3 0.0 0.4 0.0 0.0 2.2 0.0 3.1 0.3 1.9 8.8 0.0 1.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 14.1 0.8 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.1 0.1 0.0 7.6 0.0 0.0 0.1 PGLYRP3 "PGLYRPIalpha, PGRP-Ialpha, PGRPIA" ENSG00000159527 "Peptidoglycan recognition protein 3" Q96LB9 1 153297862-153310718 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 38.9;skin 1: 73.7;vagina: 21.4" "Cell type enriched" "Detected in single" 12 "Squamous epithelial cells: 4.9" "Cancer enhanced" "Detected in many" "cervical cancer: 8.9;head and neck cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "HaCaT: 3.8;HDLM-2: 1.6;hTCEpi: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA030369 Uncertain "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA030369: AB_10603984" "unprognostic (6.34e-2)" "unprognostic (1.60e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-2)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (3.88e-3)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.1 73.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 7.6 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 PGLYRP4 "PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67" ENSG00000163218 "Peptidoglycan recognition protein 4" Q96LB8 1 153330120-153348841 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 8.5;esophagus: 8.2;skin 1: 15.1;vagina: 10.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 30.1;Club cells: 9.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.7;HDLM-2: 2.2;Karpas-707: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" CAB025879 Approved "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB025879: " "unprognostic (2.76e-2)" "unprognostic (1.19e-1)" "unprognostic (6.10e-2)" "unprognostic (1.34e-2)" "unprognostic (3.61e-3)" "unprognostic (1.46e-1)" "unprognostic (3.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "unprognostic (1.88e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 15.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 2.3 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 30.1 0.6 0.0 0.0 0.1 0.3 0.0 9.7 0.0 0.0 0.0 0.0 0.1 0.0 1.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 2.0 0.0 0.3 0.3 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.4 0.0 2.4 0.0 0.0 0.0 0.3 0.0 0.0 4.0 3.4 0.3 0.0 0.0 0.2 0.2 PHACTR3 "C20orf101, PPP1R123" ENSG00000087495 "Phosphatase and actin regulator 3" Q96KR7 20 59577509-59847711 "Predicted intracellular proteins" "Actin-binding, Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 104.4;choroid plexus: 36.5" "Cell type enhanced" "Detected in many" "Astrocytes: 205.7;Excitatory neurons: 100.4;Inhibitory neurons: 88.7;Oligodendrocyte precursor cells: 218.1;Oligodendrocytes: 241.1" "Group enriched" "Detected in some" 5 "glioma: 3.8;lung cancer: 1.6;pancreatic cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 85.4;HBEC3-KT: 64.6;PC-3: 113.2;THP-1: 131.3;U-937: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051834, HPA054847" Enhanced Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA051834: AB_2681629, HPA054847: " "unprognostic (7.14e-2)" "unprognostic (1.22e-1)" "unprognostic (3.72e-2)" "unprognostic (1.43e-7)" "unprognostic (1.99e-1)" "unprognostic (2.87e-2)" "unprognostic (5.83e-3)" "unprognostic (8.92e-2)" "unprognostic (5.02e-2)" "unprognostic (2.30e-2)" "unprognostic (7.71e-2)" "unprognostic (7.22e-2)" "unprognostic (1.74e-2)" "unprognostic (1.66e-1)" "unprognostic (5.43e-2)" "unprognostic (2.53e-3)" "unprognostic (1.32e-1)" 0.9 1.2 90.4 0.5 92.4 0.5 0.4 82.0 93.4 0.3 36.5 0.8 0.7 1.0 0.7 1.1 8.6 1.9 4.0 82.3 75.4 2.2 0.6 5.9 0.1 78.5 82.4 6.2 0.2 0.0 1.7 0.6 76.1 0.1 0.8 3.3 0.1 0.0 0.2 1.1 1.0 0.3 74.7 5.5 0.5 0.5 93.7 1.9 0.1 1.0 0.1 0.5 0.1 104.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 85.4 0.0 6.2 1.3 0.0 0.2 0.3 64.6 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 1.4 0.1 10.5 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 17.9 0.3 0.4 113.2 0.0 0.0 0.7 25.1 1.4 2.1 6.5 0.5 0.0 0.1 0.0 0.5 131.3 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 90.4 92.4 82.0 93.4 82.3 75.4 78.5 82.4 76.1 74.7 93.7 104.4 0.3 12.8 0.5 205.7 0.3 0.6 1.3 2.1 0.0 13.8 0.2 0.0 8.9 10.0 8.4 3.7 0.0 0.0 0.0 0.0 1.9 1.1 1.0 7.1 3.7 0.3 1.2 0.0 100.4 0.0 0.0 4.2 0.0 2.1 0.0 0.5 3.3 0.0 0.2 5.0 88.7 0.9 44.7 0.3 1.1 0.9 0.0 3.7 0.0 7.5 0.0 0.8 0.0 218.1 241.1 2.9 0.1 0.0 0.9 2.9 4.3 0.1 1.3 1.9 0.0 2.9 0.9 0.3 1.0 0.1 0.4 0.0 0.1 0.9 4.5 3.2 PHB PHB1 ENSG00000167085 Prohibitin P35232 17 49404052-49414901 "Plasma proteins, Predicted intracellular proteins" "DNA synthesis, Host-virus interaction" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 473.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 749.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003280 Supported Supported Mitochondria "Intracellular and membrane" NA NA 360000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA003280: AB_1855732" "unprognostic (2.31e-2)" "unprognostic (5.70e-2)" "unprognostic (1.19e-2)" "unprognostic (7.88e-3)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.58e-4)" "prognostic unfavorable (9.91e-4)" "unprognostic (5.81e-2)" "unprognostic (4.40e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (7.36e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.10e-2)" "unprognostic (1.77e-1)" "unprognostic (2.71e-2)" "unprognostic (3.09e-3)" 81.6 88.4 39.2 23.3 42.2 19.8 77.4 44.2 49.8 55.3 54.0 104.5 52.6 68.0 34.1 88.6 55.7 26.9 147.0 40.6 44.4 143.4 120.4 59.0 27.0 43.9 42.5 59.7 62.5 70.1 51.1 33.1 44.1 67.2 60.0 12.1 135.9 44.7 138.1 67.5 68.0 35.7 40.9 61.1 79.7 33.5 41.9 26.2 61.5 98.5 26.8 75.2 59.4 46.0 86.0 339.1 46.4 96.9 81.9 48.3 111.8 69.8 72.3 175.1 122.4 749.5 80.2 119.2 88.1 60.0 67.3 63.4 151.7 135.3 128.4 72.9 327.1 77.7 122.8 361.8 53.0 109.6 58.1 54.9 125.9 130.9 41.6 45.7 87.6 68.6 112.7 27.6 77.5 224.0 106.0 118.5 99.9 135.9 311.1 74.9 144.0 103.8 144.0 116.1 122.1 75.9 35.4 59.1 113.7 71.7 112.2 33.4 58.9 96.3 124.7 78.4 98.4 35.3 65.7 59.1 58.0 125.6 110.7 11.7 45.9 13.4 61.6 53.4 80.5 61.2 56.6 56.3 62.3 46.7 59.4 59.7 8.9 69.0 59.5 155.1 61.4 79.8 39.2 42.2 44.2 49.8 40.6 44.4 43.9 42.5 44.1 40.9 41.9 46.0 88.5 48.1 46.8 8.8 78.3 117.5 147.5 182.6 70.0 44.8 135.7 180.0 8.4 100.1 101.9 84.6 37.5 230.2 144.4 220.8 406.9 233.1 14.0 93.4 85.5 92.6 131.9 77.2 7.8 158.6 278.7 87.8 74.9 131.0 73.0 124.6 61.4 101.8 228.1 21.9 10.0 281.7 223.8 51.9 87.9 24.7 89.5 70.9 158.3 1.9 120.3 83.1 88.6 11.1 15.3 162.8 139.8 115.1 93.0 242.8 151.4 473.6 68.0 42.1 52.6 72.8 306.5 18.0 47.3 107.6 124.0 152.4 75.9 159.9 337.2 161.9 PHB2 "Bap37, BCAP37, p22, REA" ENSG00000215021 "Prohibitin 2" Q99623 12 6965327-6970780 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014889, CAB026335, HPA039874" Supported Enhanced Mitochondria NA NA 77000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 5: NTERA-2 - Transcription" "Cluster 32: Non-specific - Translation" Mitochondria "CAB014889: , CAB026335: AB_2283865, HPA039874: AB_2616448" "unprognostic (4.64e-3)" "unprognostic (4.32e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (3.80e-4)" "unprognostic (3.07e-3)" "unprognostic (1.67e-1)" "unprognostic (2.53e-1)" "unprognostic (1.62e-1)" "unprognostic (1.98e-1)" "unprognostic (7.18e-2)" "unprognostic (1.46e-1)" "unprognostic (2.85e-1)" "unprognostic (1.04e-1)" "unprognostic (5.65e-2)" "unprognostic (1.07e-1)" "unprognostic (8.17e-2)" "unprognostic (5.61e-2)" 134.3 166.6 75.6 95.2 75.6 149.4 138.7 76.7 81.3 152.2 78.8 162.3 149.8 134.0 122.6 168.7 137.0 80.3 157.0 72.9 75.1 112.7 233.4 88.0 141.9 74.8 75.2 244.3 199.5 130.9 76.3 84.9 75.8 114.0 145.4 48.2 138.1 97.8 303.5 150.6 127.4 102.3 75.5 113.6 141.8 36.1 77.5 144.5 103.4 231.1 162.8 135.8 125.4 75.9 270.5 261.1 214.1 295.8 170.6 295.0 469.2 183.6 245.6 329.7 259.8 420.5 283.0 567.8 78.8 187.4 200.6 225.0 395.9 337.5 267.2 306.9 316.1 296.4 146.3 409.2 284.1 488.8 212.4 307.2 229.2 208.0 452.5 331.8 331.4 157.0 270.1 127.1 238.5 277.2 449.0 452.9 813.3 236.8 224.7 307.4 338.3 356.7 270.0 312.8 111.7 372.9 152.2 434.9 503.8 440.1 67.6 379.3 191.8 141.5 227.4 115.2 402.2 128.1 166.3 586.7 186.7 251.0 207.6 78.5 88.3 43.8 84.2 107.2 103.8 102.8 96.2 98.1 138.5 98.1 85.0 85.1 35.4 117.8 94.8 129.0 123.6 114.2 75.6 75.6 76.7 81.3 72.9 75.1 74.8 75.2 75.8 75.5 77.5 75.9 114.1 48.1 54.8 14.7 155.0 74.4 106.8 110.1 191.8 42.9 155.1 230.8 45.1 91.5 62.1 35.0 39.6 212.9 99.8 104.6 115.4 134.1 2.8 68.2 124.8 86.0 100.6 143.7 10.0 162.3 282.2 97.7 100.4 88.0 63.5 177.2 92.1 172.5 163.0 18.5 11.4 142.7 77.3 125.0 70.4 7.2 97.3 105.0 72.9 8.4 131.0 87.3 102.0 12.5 12.9 119.8 90.3 68.8 145.9 99.4 197.3 142.4 40.1 46.8 72.3 109.1 128.7 33.3 57.0 245.3 76.3 170.1 102.9 218.5 268.5 113.4 PHF10 "BAF45a, FLJ10975, XAP135" ENSG00000130024 "PHD finger protein 10" Q8WUB8 6 169703902-169725566 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055649 Supported Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA055649: AB_2682875" "unprognostic (1.74e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-2)" "unprognostic (4.25e-2)" "unprognostic (4.45e-2)" "unprognostic (6.76e-3)" "prognostic unfavorable (3.42e-4)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" "prognostic favorable (1.12e-5)" "unprognostic (5.92e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.63e-1)" "unprognostic (6.82e-2)" "unprognostic (2.43e-1)" "unprognostic (2.76e-2)" 41.9 78.5 49.1 39.0 55.4 53.4 40.9 52.2 53.9 43.1 46.3 49.2 32.3 40.0 39.2 46.7 39.7 34.6 46.5 43.0 54.2 38.4 52.4 40.4 61.7 52.5 56.2 80.7 41.0 47.7 36.3 43.7 54.8 48.4 34.6 59.1 44.5 44.7 81.3 50.9 40.7 33.4 56.6 49.8 42.7 41.7 55.0 53.2 48.6 63.7 61.3 42.3 41.9 57.4 31.2 30.7 119.2 125.5 40.7 24.5 49.0 41.2 37.3 49.8 54.3 88.9 31.4 91.1 24.4 29.2 31.7 38.4 92.5 45.3 72.0 73.3 82.1 91.1 54.8 116.9 41.5 134.2 5.4 18.5 46.7 32.1 29.4 82.3 80.2 64.4 102.7 57.5 36.0 53.4 25.6 115.0 37.6 68.3 18.9 121.0 84.4 73.7 62.1 32.5 56.7 75.9 56.4 18.4 41.5 49.7 36.3 158.6 54.0 28.1 46.6 36.3 53.2 50.7 46.1 112.3 36.7 88.6 45.6 1.6 1.4 3.2 1.5 1.5 1.4 2.6 2.7 2.1 1.4 1.7 2.6 2.8 0.2 1.2 1.6 1.2 1.8 0.8 49.1 55.4 52.2 53.9 43.0 54.2 52.5 56.2 54.8 56.6 55.0 57.4 42.5 25.6 30.1 17.9 24.5 29.8 22.7 13.3 13.1 12.1 38.1 31.8 59.3 35.8 23.7 11.0 41.7 14.8 25.9 11.0 13.7 12.5 15.3 32.1 27.4 28.2 25.9 7.4 14.9 12.6 8.9 27.6 12.8 42.1 6.3 38.1 29.3 27.5 11.6 11.8 19.0 22.8 18.3 13.9 28.7 9.7 22.4 21.5 19.6 28.1 11.8 33.4 10.3 17.6 33.6 17.1 19.4 21.1 16.4 27.6 18.6 12.4 22.7 26.8 19.7 27.9 53.1 18.9 22.0 21.2 23.4 17.4 21.2 33.2 20.0 27.4 PHLDB3 FLJ40193 ENSG00000176531 "Pleckstrin homology like domain family B member 3" Q6NSJ2 19 43474954-43504935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.0;skin 1: 43.5" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 58.0;Urothelial cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA043425 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Plasma membrane, Cytosol" "HPA043425: AB_10797142" "unprognostic (2.50e-2)" "unprognostic (4.22e-3)" "unprognostic (3.06e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (5.22e-3)" "unprognostic (4.43e-1)" "unprognostic (1.93e-1)" "unprognostic (2.15e-1)" "unprognostic (3.60e-2)" "prognostic favorable (6.36e-6)" "unprognostic (4.62e-2)" "prognostic unfavorable (4.11e-5)" "prognostic unfavorable (5.77e-4)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (2.37e-1)" 3.7 9.2 6.3 5.6 5.5 3.5 6.4 3.9 6.4 14.4 8.9 6.1 5.0 5.3 1.1 42.0 8.0 6.1 5.7 5.1 7.8 8.1 13.9 5.6 7.7 4.5 3.8 12.7 8.0 4.2 10.5 3.1 5.8 14.8 1.7 0.8 15.6 3.7 3.7 43.5 6.6 1.9 2.8 6.6 6.3 30.1 4.5 6.2 5.0 1.0 6.8 8.2 22.4 11.3 6.9 7.2 3.0 7.4 2.6 5.3 19.1 4.9 4.3 4.8 3.3 7.3 7.2 4.1 15.2 3.0 3.8 8.0 2.1 8.6 0.9 9.9 6.8 4.6 7.4 8.8 6.5 1.8 8.5 4.5 10.7 5.1 3.1 3.7 4.3 10.2 8.3 6.1 2.4 11.0 7.2 0.4 1.8 16.6 5.8 8.3 3.9 2.8 2.3 23.3 0.1 6.4 6.3 13.5 6.2 1.8 9.7 5.8 5.4 3.1 8.2 3.8 4.7 15.8 18.8 4.7 2.9 3.4 5.3 0.2 2.3 0.3 2.4 1.4 1.8 2.2 2.2 1.8 4.4 2.4 3.2 3.0 0.5 1.8 0.1 5.1 2.3 1.7 6.3 5.5 3.9 6.4 5.1 7.8 4.5 3.8 5.8 2.8 4.5 11.3 2.7 0.0 1.7 2.6 17.1 29.1 27.2 11.6 31.9 1.0 10.0 8.0 1.9 8.6 7.6 9.2 0.0 18.5 7.6 7.1 1.9 5.5 11.3 12.9 9.6 4.6 3.0 1.7 5.1 2.4 4.5 7.3 4.6 9.8 5.7 3.2 4.6 12.6 3.6 0.0 7.0 4.3 8.2 2.8 34.7 8.9 3.7 11.2 5.4 11.2 6.7 4.1 7.2 4.0 2.0 2.1 4.7 3.4 11.6 22.0 10.5 8.5 12.7 1.9 6.6 8.6 10.9 28.2 4.8 37.7 38.4 58.0 14.3 4.6 3.7 45.1 PHLPP1 "KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP" ENSG00000081913 "PH domain and leucine rich repeat protein phosphatase 1" O60346 18 62715541-62980433 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 107.2" "Group enriched" "Detected in many" 10 "Astrocytes: 423.7;Oligodendrocyte precursor cells: 538.3;Oligodendrocytes: 1663.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "neutrophil: 4.0;T-reg: 1.3" "Group enriched" "Detected in many" 7 "granulocytes: 4.0;T-cells: 1.3" "Cell line enhanced" "Detected in all" "REH: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020200 Approved "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA020200: AB_2670383" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" "unprognostic (2.26e-1)" "unprognostic (1.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.07e-2)" "unprognostic (5.57e-2)" "unprognostic (5.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.10e-1)" "unprognostic (2.95e-1)" "unprognostic (6.03e-2)" "prognostic favorable (5.35e-8)" "unprognostic (1.52e-1)" "unprognostic (3.49e-2)" "unprognostic (8.13e-2)" "unprognostic (8.25e-2)" 5.5 14.6 46.4 1.9 74.3 7.3 6.4 49.5 59.8 4.4 17.1 5.2 5.4 4.6 1.9 7.6 3.4 4.1 3.4 45.6 46.4 3.2 16.6 3.4 2.7 61.8 58.4 4.4 7.0 5.7 7.5 5.5 53.8 4.0 5.6 16.1 10.8 3.5 4.2 12.5 4.9 3.3 47.0 1.8 4.9 10.8 58.7 4.4 4.6 3.7 3.6 5.5 4.8 107.2 13.7 5.0 20.2 6.8 3.4 2.9 15.8 4.0 3.6 7.8 8.0 11.1 8.0 9.1 2.4 6.1 3.1 16.3 10.5 6.4 10.0 28.4 8.8 3.1 5.4 20.6 4.8 4.7 1.5 3.0 4.1 8.4 7.6 6.4 5.6 4.9 8.0 17.9 7.6 3.0 3.5 4.1 8.2 2.7 4.9 32.7 11.5 11.1 4.5 17.5 9.3 3.7 4.4 9.9 8.2 11.8 4.4 13.3 7.2 6.4 3.0 3.9 9.4 2.0 1.1 10.6 3.8 5.4 5.0 0.0 0.1 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.2 0.0 4.0 0.3 0.1 0.2 1.3 0.1 46.4 74.3 49.5 59.8 45.6 46.4 61.8 58.4 53.8 47.0 58.7 107.2 10.1 3.2 1.5 423.7 1.9 16.8 5.0 2.9 8.0 21.2 12.1 11.3 4.1 11.5 6.3 0.0 29.2 12.9 3.3 8.4 1.9 3.8 33.5 13.7 6.0 8.1 12.1 3.8 80.1 4.1 5.8 7.0 10.2 26.6 2.5 9.6 5.3 21.5 2.4 26.9 64.7 8.5 2.0 2.5 9.8 36.4 5.9 5.8 24.9 79.6 2.6 83.6 2.1 538.3 1663.2 4.5 8.0 3.8 1.0 7.5 7.4 1.9 10.0 17.4 0.0 13.5 5.3 8.0 15.4 13.2 18.6 26.1 2.7 8.3 11.1 11.0 PHOSPHO1 ENSG00000173868 "Phosphoethanolamine/phosphocholine phosphatase 1" Q8TCT1 17 49223366-49230787 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Mineral balance" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 103.0" "Cell type enriched" "Detected in some" 6 "Late spermatids: 1499.6" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 160 "eosinophil: 171.1;neutrophil: 426.7" "Lineage enriched" "Detected in many" 228 "granulocytes: 426.7" "Cell line enhanced" "Detected in some" "Daudi: 5.7;EFO-21: 3.2;HDLM-2: 4.1;SuSa: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065025 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Actin filaments" "Plasma membrane" "HPA065025: AB_2732727" "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (7.53e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-1)" "unprognostic (4.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-2)" "unprognostic (2.04e-1)" "unprognostic (6.88e-2)" "unprognostic (1.02e-2)" "unprognostic (2.88e-1)" "unprognostic (2.03e-1)" "unprognostic (1.45e-1)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (1.87e-1)" 2.5 1.3 1.5 3.4 3.4 19.0 0.5 6.3 3.9 0.4 0.6 0.7 2.9 0.7 0.2 1.0 1.3 2.2 1.8 1.8 7.3 1.3 1.0 2.3 1.6 8.8 6.2 0.3 1.2 0.2 0.6 6.4 7.4 0.8 0.0 0.7 1.2 0.3 3.4 1.3 3.0 0.4 6.9 14.2 0.9 103.0 5.5 0.3 0.7 3.2 0.2 0.9 0.5 6.1 0.0 1.0 0.0 0.8 0.1 0.1 0.0 0.2 0.2 0.0 0.1 1.5 0.0 5.7 3.2 0.0 2.1 0.0 0.9 0.3 0.1 4.1 0.1 0.7 0.7 0.2 0.0 0.0 0.6 0.2 0.0 0.3 0.0 0.4 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.7 1.2 2.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 5.4 0.1 0.1 2.2 0.3 1.7 1.1 0.0 0.1 0.2 0.3 1.5 2.0 0.1 0.2 0.6 171.1 0.4 1.5 0.3 0.1 0.1 0.2 0.4 0.0 0.0 0.2 426.7 0.5 1.8 0.0 0.1 1.1 1.5 3.4 6.3 3.9 1.8 7.3 8.8 6.2 7.4 6.9 5.5 6.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.2 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.1 0.3 0.0 0.0 0.0 205.8 0.0 0.0 1.4 0.0 8.6 0.7 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.4 0.0 2.6 0.0 1.4 0.0 0.0 0.3 0.0 1499.6 7.8 0.6 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 11.2 4.5 0.0 0.0 237.6 0.1 0.0 0.1 0.1 PI15 P25TI ENSG00000137558 "Peptidase inhibitor 15" O43692 8 74824534-74855029 "Predicted secreted proteins" "Developmental protein, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.4;prostate: 31.0;smooth muscle: 49.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 36.8;Breast glandular cells: 73.2;Breast myoepithelial cells: 13.6;Prostatic glandular cells: 19.3;Smooth muscle cells: 36.2;Urothelial cells: 15.7" "Group enriched" "Detected in many" 7 "breast cancer: 11.1;melanoma: 8.6;prostate cancer: 18.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 23.3;SH-SY5Y: 21.3;SK-MEL-30: 30.0;U-266/70: 7.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 6.3" "HPA006593, HPA030057" Uncertain Approved Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" Vesicles Cytosol "HPA006593: AB_1078568, HPA030057: AB_10602143" "unprognostic (2.77e-1)" "unprognostic (1.57e-2)" "unprognostic (3.41e-1)" "unprognostic (1.88e-2)" "unprognostic (3.22e-1)" "unprognostic (3.24e-1)" "unprognostic (2.94e-2)" "unprognostic (2.33e-3)" "unprognostic (1.87e-1)" "unprognostic (2.25e-1)" "unprognostic (3.65e-2)" "unprognostic (1.85e-2)" "unprognostic (8.63e-14)" "unprognostic (2.54e-3)" "unprognostic (1.34e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" 5.8 1.1 0.6 54.4 0.8 0.0 22.1 0.1 1.6 11.0 0.0 7.8 0.2 19.8 2.1 2.5 20.9 1.5 1.8 0.9 0.9 0.9 0.2 2.2 0.6 0.7 0.8 6.3 0.3 0.0 0.5 0.3 0.4 31.0 4.6 0.6 2.0 6.8 0.4 0.4 4.6 49.9 1.1 1.3 0.7 0.5 2.4 0.4 0.6 0.2 0.2 8.3 6.5 0.6 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.1 21.3 0.0 0.1 30.0 0.4 0.5 0.5 0.0 0.0 0.5 0.0 0.1 7.9 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.1 1.6 0.9 0.9 0.7 0.8 0.4 1.1 2.4 0.6 0.2 0.0 0.0 2.3 0.1 0.1 36.8 0.0 0.6 0.2 73.2 13.6 0.5 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 1.6 0.2 9.1 2.5 0.0 0.0 4.3 0.0 0.4 3.9 0.5 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.6 1.9 0.9 0.2 3.6 1.0 0.0 0.0 0.0 0.5 2.0 0.0 0.0 0.0 0.1 19.3 0.0 0.1 0.0 0.5 0.0 1.7 36.2 0.0 0.0 0.4 0.0 0.1 0.4 0.0 0.0 15.7 PI3 "cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14" ENSG00000124102 "Peptidase inhibitor 3" P19957 20 45174902-45176544 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2267.8;lymphoid tissue: 2103.1;vagina: 1595.8" "Group enriched" "Detected in many" 10 "Basal respiratory cells: 5354.5;Club cells: 2170.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 2666.5" "Group enriched" "Detected in some" 22 "cerebral cortex: 12.0;pons: 7.3;thalamus: 19.0" "Immune cell enriched" "Detected in some" 1021 "neutrophil: 1763.3" "Lineage enriched" "Detected in single" 4377 "granulocytes: 1763.3" "Group enriched" "Detected in many" 5 "EFO-21: 89.3;HaCaT: 109.8;OE19: 103.7;PC-3: 189.9" "CAB009449, HPA017737" Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 1400000 "Cluster 1: Neutrophils - Mixed function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB009449: AB_2252354, HPA017737: AB_1848107" "prognostic favorable (6.94e-4)" "unprognostic (3.61e-2)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (7.34e-2)" "unprognostic (1.85e-1)" "unprognostic (3.20e-3)" "unprognostic (5.53e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.84e-6)" "prognostic unfavorable (6.89e-4)" "unprognostic (8.54e-3)" "prognostic unfavorable (1.94e-8)" "unprognostic (1.23e-1)" "unprognostic (7.38e-2)" "unprognostic (1.04e-2)" "unprognostic (5.91e-3)" 6.1 0.7 0.2 101.9 0.5 1.8 8.8 0.2 12.0 180.1 1.2 124.3 1.9 2.3 1.1 2267.8 4.8 56.6 1.7 0.2 0.4 1.5 3.3 32.5 0.4 0.3 0.3 0.7 1.6 0.2 2.8 1.1 7.3 11.7 43.3 0.0 460.8 3.5 0.6 78.6 42.3 7.5 0.3 20.0 9.0 0.5 19.0 90.6 0.8 1.9 2103.1 44.7 1595.8 0.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 7.7 0.4 0.0 3.1 2.1 1.4 89.3 0.0 1.1 109.8 0.0 23.2 0.1 1.2 0.0 0.5 6.3 0.9 0.0 0.7 0.0 0.0 21.7 17.8 1.9 0.0 0.1 0.0 1.3 0.2 0.0 0.0 0.1 0.1 0.2 103.7 189.9 0.0 1.0 0.0 21.9 0.4 0.0 0.0 15.7 2.1 0.1 0.0 0.0 0.0 0.8 1.0 10.9 0.3 0.9 0.3 1.8 0.4 14.3 0.7 0.1 0.3 0.4 1.7 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 1763.3 0.0 0.1 0.1 0.1 0.6 0.2 0.5 0.2 12.0 0.2 0.4 0.3 0.3 7.3 0.3 19.0 0.3 0.1 0.0 8.6 0.0 7.4 0.1 4.7 5354.5 0.0 0.0 39.4 8.4 0.2 8.6 2170.2 18.4 0.0 0.2 0.5 375.4 0.0 46.6 0.1 3.7 0.7 3.0 16.6 0.0 0.0 317.3 0.0 0.8 2.6 6.9 4.5 0.0 0.0 0.0 0.1 0.0 0.0 31.8 197.4 0.0 0.4 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 231.8 219.6 0.0 0.2 29.1 33.9 0.2 152.9 0.0 0.0 0.0 50.5 0.0 0.0 36.2 3.8 0.0 2.5 0.1 154.1 150.4 PIANP "C12orf53, DKFZp547D2210, PANP" ENSG00000139200 "PILR alpha associated neural protein" Q8IYJ0 12 6693791-6700815 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 90.4" "Group enriched" "Detected in some" 4 "Bipolar cells: 16.1;Excitatory neurons: 24.4;Horizontal cells: 18.5;Inhibitory neurons: 23.9;Oligodendrocyte precursor cells: 16.1;Peritubular cells: 13.9;Spermatogonia: 6.7" "Group enriched" "Detected in many" 4 "glioma: 14.7;testis cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 9.9;HAP1: 9.8;hTERT-RPE1: 16.2;NTERA-2: 20.8;SH-SY5Y: 19.4;U-2 OS: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010631 Enhanced Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA010631: AB_10603680" "unprognostic (1.82e-1)" "unprognostic (9.21e-3)" "unprognostic (1.62e-2)" "unprognostic (7.65e-2)" "unprognostic (1.34e-1)" "unprognostic (3.03e-2)" "unprognostic (6.58e-2)" "unprognostic (1.07e-1)" "unprognostic (1.70e-1)" "unprognostic (6.41e-3)" "unprognostic (1.92e-2)" "unprognostic (3.89e-1)" "unprognostic (3.30e-3)" "unprognostic (3.26e-3)" "unprognostic (1.16e-1)" "unprognostic (2.30e-1)" "unprognostic (2.34e-2)" 0.4 5.4 66.0 0.9 54.9 0.0 0.8 14.6 90.4 17.8 0.0 4.8 0.6 21.1 2.2 0.8 7.5 1.7 1.0 59.8 56.9 0.9 0.2 1.0 1.1 12.1 36.1 3.3 0.7 5.4 15.6 0.3 23.1 5.5 0.6 7.9 0.8 5.5 0.2 0.5 3.0 5.1 7.3 0.6 2.3 4.0 40.6 0.0 0.9 0.4 0.4 3.7 10.1 52.9 0.0 0.5 7.4 1.4 0.2 0.4 0.2 2.0 9.9 5.1 4.6 0.1 0.2 0.2 0.0 3.5 0.8 0.2 9.8 0.3 2.4 0.3 1.3 0.4 0.3 0.0 0.3 0.4 0.3 1.2 0.0 2.0 0.0 16.2 0.0 3.0 0.0 0.3 0.5 0.2 0.3 0.3 20.8 0.0 0.1 1.4 0.1 0.2 0.1 0.1 2.6 19.4 0.1 0.1 0.0 1.3 0.1 0.0 0.0 5.2 10.5 5.5 1.4 0.2 0.0 0.3 7.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.0 54.9 14.6 90.4 59.8 56.9 12.1 36.1 23.1 7.3 40.6 52.9 0.2 0.0 0.0 3.6 0.1 0.3 0.0 0.0 0.0 16.1 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.8 0.3 3.5 0.2 0.0 0.0 24.4 0.0 0.0 1.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 18.5 23.9 0.0 0.0 0.0 0.2 1.1 2.1 0.0 0.0 3.7 0.0 3.9 0.0 16.1 3.1 0.0 0.0 13.9 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 1.6 0.1 6.7 0.0 0.1 0.1 0.3 0.0 0.0 0.1 PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.0;Inhibitory neurons: 142.2;Langerhans cells: 210.4;Microglial cells: 179.9;Oligodendrocyte precursor cells: 543.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Cell line enhanced" "Detected in many" "ASC diff: 54.5;hTEC/SVTERT24-B: 86.1;LHCN-M2: 57.3;REH: 62.3;RH-30: 90.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" 31.2 29.5 18.8 13.9 20.8 2.9 25.8 9.0 21.2 30.2 9.0 37.6 5.5 22.9 8.9 12.0 33.9 12.7 17.0 20.6 15.5 5.6 62.2 24.4 4.4 14.8 30.5 31.0 13.8 1.5 8.8 26.1 13.6 19.2 21.5 3.8 10.2 14.8 13.1 20.0 25.1 16.7 11.8 20.3 25.5 5.5 21.4 3.4 16.6 20.8 3.6 30.9 27.0 13.8 0.0 1.9 0.0 0.0 54.5 10.5 0.1 9.2 34.7 5.8 7.1 0.7 0.0 0.0 0.2 13.0 18.0 1.7 0.0 1.7 7.8 0.0 0.0 0.0 4.0 0.1 22.3 0.0 0.1 19.8 15.5 86.1 14.0 16.1 0.0 0.0 0.0 0.1 57.3 0.1 0.1 0.0 0.9 7.6 5.2 62.3 90.7 0.1 1.1 0.0 1.8 2.3 19.4 1.8 0.1 0.7 0.2 0.0 0.0 22.3 8.3 21.1 8.8 0.1 0.0 0.0 29.3 0.1 3.7 0.0 71.1 0.0 0.0 79.4 0.4 0.2 0.0 0.2 83.6 0.0 0.0 0.0 1.5 0.0 16.7 0.4 0.3 28.4 18.8 20.8 9.0 21.2 20.6 15.5 14.8 30.5 13.6 11.8 21.4 13.8 4.0 6.4 70.9 53.8 1.6 15.6 6.1 13.5 6.8 5.7 0.9 1.7 2.6 8.6 11.1 0.0 0.0 1.9 0.2 75.7 0.0 2.5 0.1 1.4 37.8 4.1 4.9 0.4 121.0 4.0 31.5 107.3 1.1 4.4 6.3 7.8 4.2 135.0 3.3 0.0 142.2 11.9 4.1 42.5 210.4 1.9 88.0 50.1 21.4 179.9 35.2 14.0 1.0 543.4 3.5 1.6 24.2 75.2 0.5 21.9 39.5 0.3 2.5 1.3 0.0 4.8 8.7 0.4 2.1 1.4 14.5 4.8 2.4 41.0 36.0 1.4 PIGK "GPI8, hGPI8" ENSG00000142892 "Phosphatidylinositol glycan anchor biosynthesis class K" Q92643 1 77088989-77219430 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Hydrolase, Protease, Thiol protease" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056383, HPA057040" Uncertain "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA056383: AB_2683109, HPA057040: AB_2683319" "unprognostic (2.43e-2)" "unprognostic (2.60e-1)" "unprognostic (4.07e-2)" "unprognostic (2.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (4.68e-4)" "unprognostic (1.07e-1)" "unprognostic (5.19e-1)" "unprognostic (1.12e-1)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (1.76e-2)" "unprognostic (3.37e-1)" "unprognostic (1.38e-1)" "unprognostic (1.21e-1)" "unprognostic (8.12e-3)" 9.8 12.4 5.2 6.3 6.6 8.8 12.4 6.1 9.4 9.7 5.7 8.5 6.9 9.5 9.7 6.5 9.3 10.0 14.1 6.0 6.4 17.7 13.2 9.2 8.8 5.9 5.5 9.6 9.6 16.3 6.5 6.4 6.2 11.2 9.3 9.8 9.5 8.8 7.0 4.8 7.3 10.7 6.8 9.8 8.9 6.0 5.5 8.5 16.3 9.8 7.5 9.3 4.2 9.8 12.3 14.2 11.5 14.7 64.1 48.1 18.6 24.4 33.1 25.0 35.6 11.8 12.2 10.7 24.4 43.1 29.7 10.8 14.8 20.8 45.2 22.1 15.1 14.6 13.8 11.1 14.4 32.5 12.4 29.2 11.1 26.7 22.9 29.9 37.4 13.2 18.0 35.6 39.0 8.3 10.3 13.2 10.4 13.7 23.4 12.0 33.7 13.3 31.9 8.9 9.7 9.1 23.2 20.8 27.1 18.9 10.0 18.5 21.5 40.1 15.6 21.9 25.0 16.1 23.7 10.7 29.8 40.5 16.2 7.2 3.0 5.8 5.8 3.4 6.0 3.7 6.0 5.0 5.7 3.2 7.5 6.8 1.5 7.4 3.5 3.9 9.8 4.7 5.2 6.6 6.1 9.4 6.0 6.4 5.9 5.5 6.2 6.8 5.5 9.8 17.7 9.6 9.1 16.3 14.4 9.6 15.2 23.7 5.2 14.2 21.0 14.2 23.0 18.6 18.3 40.5 2.1 16.0 14.1 9.7 3.9 20.8 2.1 15.6 15.5 18.1 10.8 16.4 51.4 21.1 35.7 29.3 6.6 14.1 17.7 14.7 20.3 29.3 20.3 8.4 40.2 12.4 24.4 14.5 13.9 3.7 19.6 11.9 19.6 26.2 9.2 17.6 18.6 40.7 78.2 11.9 8.5 27.4 41.7 10.1 9.3 23.3 25.3 12.4 52.6 16.3 24.1 75.8 30.2 9.4 11.9 15.2 15.5 12.7 12.7 11.5 PIGL ENSG00000108474 "Phosphatidylinositol glycan anchor biosynthesis class L" Q9Y2B2 17 16217191-16351797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "GPI-anchor biosynthesis" Hydrolase "Deafness, Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 46.7;Inhibitory neurons: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012739 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" No No "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA012739: AB_1855367" "unprognostic (3.07e-2)" "unprognostic (2.65e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" "unprognostic (7.70e-2)" "unprognostic (6.14e-2)" "unprognostic (9.39e-5)" "unprognostic (1.11e-2)" "unprognostic (1.15e-2)" "unprognostic (1.63e-2)" "unprognostic (6.37e-3)" "prognostic unfavorable (2.57e-4)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.19e-2)" "unprognostic (2.13e-1)" "unprognostic (3.38e-1)" "unprognostic (2.75e-3)" 9.6 8.6 8.0 6.3 8.4 5.6 10.1 9.7 10.4 8.6 8.5 8.8 10.6 8.3 11.8 8.1 8.9 6.1 5.6 7.8 8.5 9.0 14.3 7.7 7.8 7.8 7.8 10.4 10.2 6.1 10.4 6.3 8.2 9.8 8.4 6.3 8.2 6.1 5.3 11.4 10.1 5.9 7.6 7.8 10.5 8.7 8.2 6.4 10.1 3.3 8.3 7.8 8.1 9.4 12.5 16.3 11.4 9.3 16.0 15.2 4.6 6.3 8.0 10.8 19.5 17.2 15.4 6.6 13.7 6.7 6.9 17.4 14.7 8.2 15.0 13.1 38.3 12.3 13.6 21.9 17.3 5.0 7.4 12.5 20.3 19.1 22.0 10.9 13.0 20.1 14.6 7.3 8.6 11.1 9.3 11.6 4.5 25.2 8.3 9.0 9.7 15.6 12.3 6.6 6.0 8.5 6.7 4.9 14.6 29.9 5.4 4.5 7.6 9.1 6.0 6.6 19.8 5.5 0.2 10.3 12.2 12.5 6.2 0.0 2.7 4.7 4.6 2.6 4.1 3.7 6.3 3.7 2.0 2.8 6.4 5.5 0.0 4.8 1.8 5.3 5.4 2.5 8.0 8.4 9.7 10.4 7.8 8.5 7.8 7.8 8.2 7.6 8.2 9.4 8.5 9.6 21.0 19.2 10.0 4.5 9.2 9.1 11.4 11.5 9.8 9.8 2.4 7.2 13.0 12.9 10.4 15.6 9.3 7.3 5.9 6.3 3.0 7.7 11.4 6.6 7.8 11.6 46.7 7.5 8.0 8.8 11.7 6.9 5.1 14.0 5.0 10.5 5.2 6.7 45.3 11.2 10.2 3.5 4.3 2.9 7.8 5.9 3.6 26.2 3.6 5.2 9.2 24.6 34.9 9.4 9.7 11.3 12.2 8.3 9.8 5.9 10.6 12.2 0.0 9.1 7.3 16.1 8.3 7.5 6.0 9.6 11.8 9.4 12.6 10.4 PIGT ENSG00000124155 "Phosphatidylinositol glycan anchor biosynthesis class T" Q969N2 20 45416084-45456934 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.06e-2)" "unprognostic (4.60e-3)" "unprognostic (7.63e-2)" "unprognostic (6.00e-2)" "unprognostic (6.18e-3)" "unprognostic (6.68e-2)" "unprognostic (7.34e-3)" "unprognostic (1.17e-1)" "unprognostic (2.70e-2)" "unprognostic (3.32e-1)" "prognostic favorable (2.51e-4)" "unprognostic (5.48e-2)" "unprognostic (7.60e-2)" "unprognostic (9.21e-2)" "unprognostic (5.66e-2)" "unprognostic (1.06e-1)" "unprognostic (3.43e-2)" 57.4 51.9 30.7 39.4 38.9 70.8 52.7 41.2 37.5 65.5 44.6 75.8 49.9 69.6 89.5 37.7 61.2 48.3 113.5 29.9 37.2 47.1 48.9 45.3 26.6 41.0 38.1 46.1 65.0 105.4 48.9 48.5 38.9 39.5 77.2 13.0 48.2 55.6 61.2 46.0 54.3 69.7 37.6 36.5 62.1 38.1 38.8 25.8 57.0 51.8 27.4 57.0 42.8 47.6 79.0 95.3 35.8 138.7 218.0 152.9 68.5 90.4 172.8 126.8 99.7 179.9 123.6 47.1 122.0 142.9 108.4 152.4 43.6 124.8 67.8 25.2 53.5 49.0 80.8 100.9 99.9 93.5 203.1 117.3 117.0 99.9 108.6 179.4 109.3 39.2 65.0 163.8 107.4 165.3 44.8 74.7 29.4 227.5 162.1 38.0 107.6 168.0 102.5 51.1 60.2 77.0 177.7 173.2 88.7 61.4 150.6 169.8 96.5 301.4 138.1 57.1 128.8 93.9 144.0 30.0 190.7 74.7 140.9 58.9 77.9 66.3 57.4 83.2 43.6 27.2 41.0 53.8 92.2 28.1 35.7 41.8 30.7 57.6 79.2 71.4 61.6 83.1 30.7 38.9 41.2 37.5 29.9 37.2 41.0 38.1 38.9 37.6 38.8 47.6 41.9 41.7 29.5 9.1 43.9 30.0 46.4 86.8 13.6 21.0 43.7 31.4 169.2 41.5 63.7 44.1 14.6 62.1 58.9 106.1 13.7 107.5 31.8 45.2 32.3 46.0 65.5 24.2 7.6 114.5 73.9 94.2 44.9 59.2 33.6 58.5 39.7 41.5 76.8 38.7 9.8 145.3 85.5 49.6 42.6 81.4 60.6 44.3 88.9 4.7 39.8 25.8 37.0 6.0 27.1 79.5 61.8 56.1 69.2 40.7 103.8 26.1 46.2 15.6 65.7 39.4 47.2 88.4 96.9 23.5 27.8 52.1 43.4 47.9 111.6 57.7 PIGZ "FLJ12768, MGC52163, SMP3" ENSG00000119227 "Phosphatidylinositol glycan anchor biosynthesis class Z" Q86VD9 3 196946356-196969060 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 39.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 205.1;Intestinal goblet cells: 61.3;Paneth cells: 129.7;Proximal enterocytes: 50.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA058599, HPA059920" Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA058599: AB_2683771, HPA059920: AB_2684162" "unprognostic (1.46e-1)" "unprognostic (3.18e-3)" "unprognostic (1.06e-2)" "unprognostic (3.31e-2)" "unprognostic (3.90e-2)" "unprognostic (8.16e-2)" "unprognostic (4.25e-3)" "unprognostic (4.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.31e-1)" "unprognostic (5.44e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (1.02e-1)" "unprognostic (3.93e-2)" "unprognostic (8.38e-5)" "unprognostic (5.02e-3)" 6.7 1.6 8.2 2.0 8.5 1.0 5.4 8.6 9.6 4.3 4.4 39.1 1.6 3.4 0.7 4.2 3.4 2.0 6.9 8.1 9.2 2.1 2.6 3.7 1.1 7.6 8.6 0.8 2.7 3.0 4.1 1.0 10.0 6.1 16.7 3.1 4.7 2.6 7.4 4.7 11.7 2.7 5.3 1.9 4.6 1.6 8.6 1.2 1.9 3.2 0.5 10.4 4.6 7.7 1.8 1.2 0.7 2.8 7.7 3.7 0.7 2.6 7.3 2.0 1.6 1.7 1.5 0.3 5.1 5.9 1.3 3.0 0.1 0.4 0.5 0.5 0.3 0.8 0.6 6.5 3.6 0.0 2.9 3.7 5.6 0.3 0.9 2.2 2.4 4.7 0.2 2.2 1.9 3.2 0.3 1.5 0.1 2.2 0.9 0.4 0.1 0.6 3.0 3.3 1.1 1.2 3.7 0.3 1.5 0.3 7.2 2.6 6.0 1.6 0.4 4.7 0.9 1.0 0.1 0.1 0.4 1.1 0.6 0.0 0.3 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 8.2 8.5 8.6 9.6 8.1 9.2 7.6 8.6 10.0 5.3 8.6 7.7 8.9 0.0 1.1 20.5 1.7 7.8 9.1 3.8 6.8 7.1 22.6 33.9 8.0 1.5 2.8 9.2 2.1 0.0 2.8 205.1 5.9 2.3 2.1 5.1 3.0 5.5 13.8 3.0 31.3 3.6 0.0 5.0 1.5 6.5 5.7 0.3 12.1 10.3 1.8 15.2 21.9 61.3 10.2 4.4 3.4 5.0 4.1 2.2 8.8 5.6 4.1 4.6 2.1 12.5 2.7 3.2 129.7 6.4 1.9 7.4 50.0 5.4 2.7 7.0 0.0 7.7 6.5 1.2 0.2 11.5 5.1 0.1 1.7 0.0 44.4 14.7 PIK3AP1 "BCAP, FLJ35564" ENSG00000155629 "Phosphoinositide-3-kinase adaptor protein 1" Q6ZUJ8 10 96593315-96720514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 83.2;lymphoid tissue: 62.3;salivary gland: 73.6" "Cell type enhanced" "Detected in many" "B-cells: 53.7;Hepatocytes: 70.7;Kupffer cells: 127.0;Macrophages: 89.8;Microglial cells: 60.9;monocytes: 57.4;NK-cells: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 44.7;memory B-cell: 48.3;naive B-cell: 44.5;non-classical monocyte: 123.0" "Group enriched" "Detected in all" 6 "B-cells: 48.3;monocytes: 123.0" "Cell line enhanced" "Detected in many" "Daudi: 85.3;NB-4: 62.1;REH: 183.5;THP-1: 92.9;U-698: 114.7;U-937: 95.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026136, HPA038452" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" Cytosol "Nucleoplasm, Plasma membrane" "CAB026136: , HPA038452: AB_2676019" "unprognostic (2.83e-2)" "unprognostic (4.61e-3)" "unprognostic (7.32e-2)" "unprognostic (1.70e-1)" "unprognostic (1.79e-1)" "unprognostic (1.49e-1)" "unprognostic (4.60e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" "unprognostic (2.10e-1)" "unprognostic (5.11e-2)" "unprognostic (1.28e-1)" "unprognostic (4.69e-2)" "unprognostic (5.45e-1)" "unprognostic (1.13e-1)" 8.1 4.5 2.1 51.1 2.0 47.5 4.7 2.4 3.2 2.8 2.7 7.3 6.8 2.1 1.7 2.4 2.2 24.8 2.5 1.9 2.9 11.8 83.2 16.7 61.2 6.5 4.6 6.0 22.8 2.0 1.4 14.1 5.3 2.8 8.6 3.1 73.6 2.4 0.7 1.0 7.7 8.3 4.7 62.3 6.9 3.0 5.7 8.7 4.1 3.1 57.8 15.2 0.6 7.6 0.2 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.9 1.2 2.8 1.5 85.3 8.5 0.0 1.3 0.1 17.7 0.0 0.6 48.0 3.0 13.0 0.0 1.7 0.1 36.1 6.7 0.0 0.0 0.1 0.0 0.1 0.0 3.1 0.9 0.1 0.1 0.4 1.1 62.1 0.8 24.3 1.0 183.5 4.3 20.0 0.2 0.1 3.6 2.0 0.2 0.2 1.1 0.3 0.2 92.9 0.0 0.0 2.8 0.1 0.7 0.7 0.2 114.7 0.0 95.2 0.0 6.1 16.0 10.5 13.3 44.7 4.7 48.3 0.3 4.1 12.9 44.5 0.1 3.3 13.5 14.0 123.0 11.3 0.5 14.4 2.1 2.0 2.4 3.2 1.9 2.9 6.5 4.6 5.3 4.7 5.7 7.6 0.5 3.2 3.9 1.3 53.7 1.5 0.1 0.1 0.6 0.6 2.2 2.3 2.6 32.9 2.2 1.8 2.1 0.5 41.5 8.1 1.9 40.0 4.3 0.3 0.1 1.8 1.8 10.3 0.8 29.1 0.9 0.7 0.0 0.2 14.0 0.2 5.7 70.7 47.7 0.0 0.8 2.8 4.1 127.0 32.5 1.0 1.2 89.8 5.4 60.9 57.4 0.2 58.7 1.0 0.3 16.4 21.2 2.2 9.4 0.4 1.6 18.3 1.1 3.4 0.0 0.6 0.8 0.8 0.2 0.3 1.1 2.3 18.3 0.4 3.8 0.3 PIK3CG ENSG00000105851 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma" P48736 7 106865278-106908980 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Endocytosis, Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 43.6;lymphoid tissue: 19.7" "Cell type enhanced" "Detected in some" "B-cells: 24.9;dendritic cells: 26.5;Early spermatids: 28.9;granulocytes: 20.8;monocytes: 23.8;NK-cells: 25.7;Plasma cells: 88.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 29.4;HL-60: 28.8;HMC-1: 34.9;Karpas-707: 29.1;MOLT-4: 56.0;U-266/70: 71.4;U-937: 52.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069976 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" Cytosol "HPA069976: AB_2686224" "unprognostic (8.34e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (3.20e-2)" "unprognostic (3.82e-3)" "unprognostic (3.02e-1)" "unprognostic (6.77e-2)" "unprognostic (1.16e-1)" "unprognostic (7.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (9.08e-2)" "unprognostic (1.23e-1)" "unprognostic (5.38e-1)" "unprognostic (5.24e-2)" 3.1 1.8 0.5 11.5 0.6 43.6 1.9 0.8 1.3 1.9 1.3 4.2 4.1 1.3 0.5 1.7 1.4 3.2 1.6 0.5 1.0 1.0 2.0 4.9 19.0 2.5 1.3 1.6 0.3 0.7 0.2 2.9 2.7 1.0 3.8 0.1 1.3 0.9 0.3 0.8 4.3 2.7 1.8 11.0 4.0 5.2 2.0 16.4 1.1 1.0 19.7 4.3 0.2 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 2.7 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 17.9 0.0 0.0 0.0 28.8 34.9 0.0 0.0 0.0 0.0 0.0 11.0 16.9 20.6 29.1 0.0 0.0 56.0 17.6 0.0 0.0 0.0 14.6 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.6 2.9 0.1 0.2 0.1 0.0 71.4 0.0 27.3 0.1 52.1 6.7 10.8 6.0 24.3 8.8 17.8 8.1 7.3 4.1 6.7 9.4 10.2 4.2 5.9 22.7 9.8 43.7 8.6 4.4 6.8 0.5 0.6 0.8 1.3 0.5 1.0 2.5 1.3 2.7 1.8 2.0 3.9 1.5 0.0 1.8 0.3 24.9 0.8 0.0 0.0 0.6 0.0 0.1 0.1 0.5 0.0 0.6 0.0 0.0 0.0 26.5 0.2 0.0 0.0 28.9 0.1 0.2 1.7 0.0 7.8 5.5 0.0 0.0 0.1 3.6 0.1 20.8 0.4 2.5 0.5 6.8 0.0 0.3 0.0 0.0 11.9 8.3 18.8 0.6 18.9 7.2 15.0 23.8 0.0 25.7 0.0 0.2 0.0 0.0 0.0 88.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 6.6 3.7 0.2 0.3 0.1 18.1 0.6 0.6 0.1 PIK3IP1 "HGFL, MGC17330, TrIP" ENSG00000100100 "Phosphoinositide-3-kinase interacting protein 1" Q96FE7 22 31281594-31292534 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 143.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 499.2" "Lineage enriched" "Detected in all" 6 "T-cells: 499.2" "Cell line enhanced" "Detected in many" "RT4: 24.1;SK-BR-3: 26.1;U-698: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes 6800000 "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.02e-1)" "unprognostic (1.97e-3)" "unprognostic (1.58e-1)" "unprognostic (4.84e-2)" "unprognostic (8.19e-2)" "unprognostic (1.61e-3)" "unprognostic (5.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.99e-1)" "unprognostic (9.95e-3)" "unprognostic (1.28e-2)" "unprognostic (2.65e-3)" "unprognostic (4.42e-2)" "unprognostic (8.68e-2)" "prognostic favorable (3.80e-4)" 51.2 41.7 35.4 59.3 42.5 41.7 39.5 38.3 40.2 21.4 23.7 35.5 17.5 34.9 13.2 21.7 24.1 27.0 34.8 33.4 39.3 27.6 9.3 45.7 109.8 53.5 40.4 22.8 11.3 16.9 15.1 25.3 48.5 27.1 15.5 11.4 52.4 31.7 20.9 58.2 61.6 22.9 43.8 71.3 24.7 20.3 42.4 68.2 37.6 16.1 79.7 34.8 27.1 52.7 0.5 0.2 0.8 0.1 11.8 20.4 0.9 3.1 9.7 0.2 1.1 0.3 20.4 15.9 11.4 4.9 1.3 13.4 0.1 5.8 0.2 2.6 1.9 0.5 2.3 2.2 4.0 1.1 0.7 20.0 8.3 0.2 0.1 18.9 6.4 2.3 0.9 19.6 1.5 1.3 0.1 2.5 0.9 1.8 0.4 1.2 0.8 11.9 5.1 24.1 1.2 2.6 1.0 26.1 1.2 10.7 2.1 2.3 20.0 0.0 4.5 0.2 0.0 8.9 4.1 34.7 0.5 2.8 0.4 46.0 18.4 16.5 79.7 22.8 95.5 38.2 207.1 113.7 5.9 79.3 499.2 318.3 7.6 59.2 34.2 2.6 257.0 214.7 35.4 42.5 38.3 40.2 33.4 39.3 53.5 40.4 48.5 43.8 42.4 52.7 26.1 44.8 12.3 17.6 63.7 10.3 19.0 44.6 5.7 29.9 15.5 11.3 11.3 10.0 36.9 31.3 10.4 30.7 89.8 8.3 1.9 50.2 1.6 10.6 10.3 20.9 8.4 12.0 6.5 10.5 3.7 23.8 10.7 24.4 30.4 10.1 32.9 2.0 45.1 6.7 8.6 13.1 32.6 42.5 11.4 3.8 24.5 40.3 12.4 9.4 19.2 82.0 74.2 9.5 25.1 51.7 8.6 30.9 33.1 23.4 19.8 7.9 25.1 9.2 6.6 10.2 14.6 16.5 32.3 4.9 11.5 12.3 143.6 27.4 10.1 60.0 PILRA FDF03 ENSG00000085514 "Paired immunoglobin like type 2 receptor alpha" Q9UKJ1 7 100367530-100400096 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 80.8;Kupffer cells: 100.7;Langerhans cells: 65.9;Leydig cells: 52.5;Macrophages: 144.7;monocytes: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1659.8;non-classical monocyte: 1146.1" "Group enriched" "Detected in all" 5 "granulocytes: 1659.8;monocytes: 1146.1" "Cell line enhanced" "Detected in some" "ASC diff: 27.9;HMC-1: 25.5;NB-4: 20.4" HPA056132 Approved "Secreted to blood" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA056132: AB_2683048" "unprognostic (5.53e-2)" "prognostic favorable (2.99e-4)" "unprognostic (7.61e-2)" "unprognostic (2.88e-1)" "unprognostic (2.20e-1)" "unprognostic (5.88e-2)" "unprognostic (1.44e-1)" "unprognostic (2.85e-1)" "unprognostic (3.01e-3)" "unprognostic (9.95e-2)" "unprognostic (8.57e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (3.47e-2)" "unprognostic (3.17e-2)" "unprognostic (1.99e-1)" "unprognostic (4.80e-2)" 14.6 9.3 7.2 38.5 7.5 26.0 8.9 13.7 9.6 10.7 7.7 7.6 4.1 8.2 4.7 3.7 14.2 9.3 5.7 6.9 9.3 12.6 9.7 30.4 9.2 12.1 9.4 9.5 5.3 3.6 15.5 11.3 11.7 11.3 5.3 3.8 5.7 4.0 5.3 5.3 8.0 9.8 9.0 31.1 5.9 10.8 9.3 5.0 9.4 2.9 3.5 17.7 6.7 15.5 0.3 0.4 0.6 0.7 27.9 1.8 0.2 0.2 1.4 0.1 0.5 0.0 0.5 0.6 1.7 0.4 0.3 0.8 0.2 0.1 0.0 1.4 1.0 0.6 1.3 0.1 0.3 1.1 25.5 2.0 0.4 0.2 0.6 0.1 0.3 2.5 0.2 1.8 0.2 0.9 2.0 20.4 0.6 0.4 0.3 0.5 0.0 0.4 1.1 0.6 0.8 0.3 0.0 6.9 0.7 0.1 0.1 6.0 0.6 1.2 1.2 0.8 0.2 2.5 2.0 0.6 0.3 2.3 0.4 316.9 584.3 18.5 2.5 863.0 2.1 2.3 0.9 1.0 288.0 1.1 1.0 1.8 1659.8 6.4 1146.1 5.4 2.2 354.1 7.2 7.5 13.7 9.6 6.9 9.3 12.1 9.4 11.7 9.0 9.3 15.5 1.0 3.2 12.4 8.8 2.7 1.8 0.3 0.9 0.0 3.6 2.1 3.0 0.6 2.8 3.9 1.8 4.2 0.6 2.1 0.6 27.4 0.2 0.7 3.9 13.1 4.1 0.0 2.7 15.9 0.4 0.6 2.8 0.5 5.8 10.1 0.8 1.8 1.8 80.8 1.7 14.8 1.3 0.0 100.7 65.9 1.9 52.5 144.7 1.8 28.1 72.3 1.4 3.1 2.0 10.3 0.3 0.1 21.4 0.4 0.5 0.1 0.7 3.1 2.4 0.0 1.0 0.7 1.6 2.6 0.2 0.9 0.8 2.0 0.4 0.9 0.3 PILRB "FDFACT1, FDFACT2" ENSG00000121716 "Paired immunoglobin like type 2 receptor beta" Q9UKJ0 7 100352176-100367733 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 221.1;neutrophil: 141.8" "Group enriched" "Detected in all" 8 "granulocytes: 221.1;monocytes: 75.5" "Cell line enhanced" "Detected in all" "SK-BR-3: 344.6" HPA026750 Approved Approved Mitochondria "Intracellular and membrane" NA Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA026750: AB_10670828" "unprognostic (8.33e-3)" "unprognostic (9.31e-2)" "unprognostic (1.32e-2)" "unprognostic (9.15e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (3.17e-1)" "unprognostic (1.20e-1)" "unprognostic (8.76e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (4.85e-3)" "unprognostic (1.66e-1)" "unprognostic (4.40e-2)" "unprognostic (3.35e-3)" 63.2 89.0 72.9 71.0 75.0 71.7 77.6 104.3 86.3 87.0 90.9 65.8 66.1 62.9 67.6 47.2 83.8 52.2 47.7 75.5 70.8 118.8 125.0 43.9 83.7 71.8 70.8 82.1 91.7 58.3 182.0 32.9 71.5 102.7 57.4 66.8 66.4 58.0 78.7 90.1 75.9 42.3 64.2 113.5 68.7 157.5 74.3 59.0 122.9 34.3 65.7 61.9 56.2 78.1 62.5 51.4 57.9 100.7 63.0 14.4 56.2 37.0 16.5 25.7 24.9 36.5 70.3 50.3 68.0 19.0 45.7 65.1 32.3 38.9 17.5 41.6 47.3 46.5 204.8 32.2 14.0 47.4 116.0 18.1 44.8 34.8 70.2 31.9 21.8 73.6 50.7 118.9 18.3 83.9 74.8 243.3 25.2 51.7 26.9 43.3 16.9 51.6 116.4 100.3 53.8 38.5 31.2 344.6 45.7 61.7 60.5 72.3 52.4 90.8 57.9 58.8 48.7 71.2 98.6 61.8 25.5 69.4 54.6 21.2 35.6 221.1 10.7 59.2 6.7 0.6 1.3 7.1 17.8 1.6 1.2 2.6 141.8 17.9 75.5 0.5 0.6 25.7 72.9 75.0 104.3 86.3 75.5 70.8 71.8 70.8 71.5 64.2 74.3 78.1 22.8 38.5 45.9 0.0 25.3 15.7 18.1 17.1 11.4 44.7 32.9 33.7 1.1 44.3 32.2 14.7 68.8 12.9 49.5 12.3 1.9 7.6 18.4 43.1 17.5 19.8 29.4 7.4 0.0 5.6 12.1 13.4 36.2 57.2 25.2 26.0 24.3 77.7 10.0 75.7 0.0 21.2 22.4 16.0 16.6 13.6 74.0 11.7 19.6 0.0 10.0 19.0 134.9 0.0 0.0 7.4 16.2 51.1 14.5 17.9 20.3 4.9 40.3 64.9 26.3 18.2 14.3 49.4 10.2 10.5 13.5 15.7 37.0 23.5 22.4 16.7 PINLYP ENSG00000234465 "Phospholipase A2 inhibitor and LY6/PLAUR domain containing" A6NC86 19 43575801-43583964 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 23.5;Proximal tubular cells: 19.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 21.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 73.1;HMC-1: 46.6;JURKAT: 37.1;REH: 29.8;THP-1: 36.6" "Not detected" "Not detected" HPA061218 Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA061218: AB_2684453" "unprognostic (6.72e-2)" "unprognostic (6.21e-2)" "unprognostic (4.72e-1)" "unprognostic (3.13e-2)" "unprognostic (2.46e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-2)" "unprognostic (5.07e-2)" "unprognostic (2.00e-1)" "unprognostic (2.85e-2)" "unprognostic (1.14e-1)" "unprognostic (4.36e-3)" "unprognostic (1.95e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "unprognostic (3.60e-2)" 9.9 3.5 16.3 3.3 16.7 2.7 8.5 18.1 22.1 17.3 16.1 13.3 1.4 14.7 9.4 10.5 17.1 9.3 9.8 16.1 16.8 22.9 2.1 7.7 5.0 17.2 17.0 19.6 2.4 0.7 14.9 2.8 16.0 13.5 3.0 2.6 5.8 10.4 1.7 7.6 6.4 11.1 16.4 8.4 7.3 5.4 17.4 10.6 11.8 3.3 5.2 10.3 13.0 15.7 0.7 0.3 1.9 0.3 3.4 4.5 0.4 0.8 1.2 1.6 4.3 0.0 0.1 0.0 0.2 19.0 1.8 4.0 0.0 0.2 1.5 0.1 0.2 73.1 0.8 0.1 10.3 0.0 46.6 10.2 0.4 10.3 0.2 4.3 2.7 37.1 0.9 1.0 0.7 0.4 8.9 1.1 1.8 0.1 0.7 29.8 0.2 0.0 0.8 0.4 0.3 0.0 0.0 0.4 0.1 0.3 0.1 36.6 1.2 4.7 0.9 0.1 3.1 0.0 0.0 4.4 16.0 0.0 0.4 10.4 1.5 0.7 3.0 1.2 3.6 1.7 0.9 2.5 2.3 4.7 0.3 3.6 0.5 1.4 0.2 21.0 2.0 1.7 16.3 16.7 18.1 22.1 16.1 16.8 17.2 17.0 16.0 16.4 17.4 15.7 1.8 12.8 3.2 2.3 1.1 3.6 10.0 5.6 8.6 6.1 2.4 5.6 2.8 8.6 5.7 9.2 6.2 0.4 1.8 0.1 23.5 1.3 6.4 2.1 9.9 4.3 0.0 4.4 0.5 0.4 0.4 9.1 2.0 2.0 0.0 7.6 5.7 0.0 5.1 6.7 1.1 0.8 2.0 1.0 3.9 7.3 11.5 2.7 5.4 1.9 3.3 5.6 0.0 5.0 0.5 0.4 0.1 9.8 1.7 5.2 0.7 19.0 15.0 3.3 0.0 2.1 5.9 2.3 1.2 6.7 3.1 0.1 1.2 13.6 1.7 6.6 PIP "GCDFP-15, GCDFP15, GPIP4" ENSG00000159763 "Prolactin induced protein" P12273 7 143132077-143139739 "Plasma proteins, Predicted secreted proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 16791.8" "Group enriched" "Detected in many" 4 "Breast glandular cells: 1117.6;Breast myoepithelial cells: 324.2;Melanocytes: 403.8" "Cancer enriched" "Detected in many" 70 "breast cancer: 672.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 333 "T-47d: 703.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB002661, HPA009177" Enhanced "Secreted in other tissues" NA NA 66000000 "Cluster 37: B-cells - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "CAB002661: , HPA009177: AB_1845459" "unprognostic (2.80e-1)" "unprognostic (2.15e-1)" "unprognostic (1.08e-3)" "unprognostic (3.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.14e-1)" "unprognostic (3.49e-2)" "unprognostic (5.55e-1)" 9.1 3.6 0.7 0.2 4.8 0.1 3458.7 2.7 2.7 5.6 0.0 0.5 0.0 0.1 2.7 1.3 4.2 0.1 4.8 0.9 4.6 0.5 2.0 6.4 0.8 8.5 4.4 3.8 21.1 0.4 1.9 2.3 6.8 33.3 0.0 0.0 16791.8 3140.5 1.7 189.7 0.6 0.0 3.5 0.6 0.6 0.7 4.6 0.3 0.7 0.0 1.8 0.6 1.5 11.5 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 1.3 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 703.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 4.8 2.7 2.7 0.9 4.6 8.5 4.4 6.8 3.5 4.6 11.5 6.9 0.0 2.0 0.0 3.6 10.8 6.6 18.8 0.0 0.0 1117.6 324.2 0.1 0.0 48.2 1.8 0.0 0.0 7.0 0.0 0.0 9.3 0.0 0.0 0.0 3.9 0.0 0.0 0.0 2.5 0.0 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.4 0.0 1.6 0.0 0.0 1.5 403.8 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 0.0 0.0 13.1 0.0 0.1 147.1 0.0 0.0 0.0 9.2 0.0 0.0 0.0 1.7 0.0 2.5 0.0 0.0 13.7 PKD1 "PBP, Pc-1, TRPP1" ENSG00000008710 "Polycystin 1, transient receptor potential channel interacting" P98161 16 2088708-2135898 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 72.4" "Cell type enhanced" "Detected in all" "Excitatory neurons: 138.1;Horizontal cells: 119.5;Inhibitory neurons: 101.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 65.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046448 Approved NA NA 840000 "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" "CAB046448: AB_2163360" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (7.43e-4)" "unprognostic (1.35e-1)" "unprognostic (1.79e-1)" "prognostic favorable (3.35e-4)" "unprognostic (1.98e-2)" "unprognostic (1.02e-2)" "unprognostic (1.81e-1)" "unprognostic (1.22e-2)" "prognostic favorable (3.38e-5)" "unprognostic (7.86e-2)" "unprognostic (4.07e-1)" "unprognostic (3.44e-2)" "unprognostic (1.19e-1)" "unprognostic (1.78e-2)" "unprognostic (2.81e-1)" 14.8 9.5 7.9 4.9 10.4 3.9 13.7 65.4 32.1 22.1 0.0 40.3 3.8 30.6 2.0 11.3 25.9 3.7 23.9 9.6 1.6 7.5 8.9 13.4 3.4 16.2 1.7 23.8 10.4 2.3 72.4 3.7 12.6 19.9 1.5 7.4 10.4 8.7 47.7 16.8 15.3 6.1 0.1 9.9 19.1 10.3 4.7 2.8 10.3 8.3 1.5 24.5 15.5 4.9 4.2 8.9 4.8 10.9 8.2 8.8 9.3 14.2 5.9 4.0 4.0 8.0 3.1 6.3 8.9 7.3 4.3 10.4 1.4 2.1 1.5 7.4 7.1 3.9 25.8 3.2 16.1 5.4 7.8 8.2 7.0 7.5 4.6 5.6 3.1 6.6 5.7 6.2 2.6 6.9 7.7 16.5 4.3 1.7 6.6 21.6 7.7 9.6 2.1 2.8 19.9 22.2 12.9 8.5 8.9 1.7 7.0 18.3 7.4 12.7 10.3 9.6 10.5 9.0 4.3 7.0 7.1 5.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 10.4 65.4 32.1 9.6 1.6 16.2 1.7 12.6 0.1 4.7 4.9 21.3 12.8 12.2 61.7 6.9 24.3 10.3 14.7 30.7 79.8 15.4 18.9 26.4 4.3 10.9 9.2 41.7 6.0 11.2 13.6 9.8 5.2 51.9 16.0 32.1 17.1 30.5 4.8 138.1 3.1 4.0 30.4 8.2 16.9 8.2 21.3 15.7 24.2 5.2 119.5 101.0 17.6 4.1 7.2 12.6 10.6 27.7 7.8 23.2 18.7 6.2 36.4 11.3 38.2 29.5 4.5 5.9 45.9 9.0 10.3 8.9 7.7 32.9 35.2 32.9 41.4 25.2 10.1 15.8 26.0 20.0 3.1 10.9 10.1 14.2 6.9 PKDCC "SgK493, Vlk" ENSG00000162878 "Protein kinase domain containing, cytoplasmic" Q504Y2 2 42048021-42058517 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Differentiation, Osteogenesis, Protein transport, Transport" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 85.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 71.9;Fibroblasts: 55.4;Leydig cells: 137.6;Peritubular cells: 112.1;Rod photoreceptor cells: 95.9;Theca cells: 135.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 85.9;ASC diff: 61.7;CACO-2: 101.0;HHSteC: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026427, HPA026442, HPA026526" Approved "Secreted to blood" NA NA 80000 "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA026427: AB_10600773, HPA026442: AB_10601237, HPA026526: AB_10602416" "unprognostic (6.77e-2)" "unprognostic (3.35e-1)" "unprognostic (1.04e-2)" "unprognostic (3.59e-3)" "unprognostic (8.31e-2)" "unprognostic (1.11e-1)" "unprognostic (2.18e-2)" "unprognostic (5.79e-3)" "unprognostic (1.04e-2)" "unprognostic (1.32e-1)" "unprognostic (3.20e-1)" "unprognostic (6.09e-2)" "unprognostic (2.14e-2)" "unprognostic (9.08e-2)" "unprognostic (2.62e-1)" "unprognostic (4.73e-3)" "unprognostic (2.58e-3)" 25.7 11.3 3.1 4.9 3.8 0.8 16.1 0.8 6.2 31.8 6.4 20.3 10.7 25.7 2.1 2.2 24.2 3.3 37.6 4.8 1.0 10.7 6.9 16.5 2.1 1.5 1.6 50.1 7.0 1.1 6.8 3.6 1.3 12.2 5.7 5.3 20.7 5.8 85.5 3.8 13.7 9.8 1.4 9.6 9.6 14.8 2.1 6.4 5.1 27.7 1.4 32.5 17.4 4.7 0.0 5.5 14.0 85.9 61.7 0.7 5.3 0.2 0.0 1.2 1.5 101.0 0.2 0.0 0.3 1.7 1.8 0.0 1.3 0.0 0.0 8.1 3.5 0.2 3.3 27.0 53.7 0.0 1.2 5.7 0.3 0.2 0.0 0.6 0.7 0.0 1.2 0.0 0.3 0.3 0.0 0.3 23.8 6.8 1.7 0.0 27.3 0.0 0.0 0.0 2.8 5.1 1.3 0.0 0.2 16.3 0.1 0.7 0.0 0.6 2.8 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 3.8 0.8 6.2 4.8 1.0 1.5 1.6 1.3 1.4 2.1 4.7 28.8 19.2 0.5 4.2 0.3 3.2 0.2 0.0 0.0 4.7 1.3 2.0 9.2 1.5 0.0 1.8 16.7 0.5 0.6 22.8 0.0 2.1 1.1 6.0 31.4 3.1 71.9 0.0 22.8 1.3 1.3 55.4 2.6 26.3 0.0 4.5 2.9 2.7 0.6 0.0 3.3 18.6 0.0 0.6 3.1 5.4 137.6 0.6 1.8 3.7 0.0 21.3 0.0 10.1 1.8 1.9 16.0 112.1 0.0 0.8 15.2 3.9 0.0 95.9 13.1 14.2 15.1 0.7 1.7 0.0 1.8 0.3 0.8 135.4 35.9 0.1 PKHD1 "ARPKD, FCYT, FPC, TIGM1" ENSG00000170927 "PKHD1 ciliary IPT domain containing fibrocystin/polyductin" P08F94 6 51615299-52087613 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 4.7;kidney: 13.6;pancreas: 9.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 60.1;Collecting duct cells: 46.0;Early spermatids: 293.6;Late spermatids: 83.1" "Group enriched" "Detected in some" 5 "pancreatic cancer: 1.4;renal cancer: 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "RPTEC TERT1: 10.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA031227 Enhanced "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" "HPA031227: AB_10602068" "unprognostic (6.34e-3)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" "unprognostic (1.35e-1)" "unprognostic (3.80e-2)" "unprognostic (1.29e-2)" "unprognostic (4.03e-2)" "unprognostic (6.42e-2)" "unprognostic (7.08e-2)" "unprognostic (2.44e-2)" "unprognostic (1.02e-2)" "unprognostic (2.62e-2)" "prognostic favorable (9.74e-8)" "unprognostic (2.33e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.48e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.1 1.1 0.0 0.0 0.0 13.6 1.5 0.0 0.0 0.1 0.1 0.0 9.4 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.3 10.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.3 1.4 60.1 0.0 46.0 0.0 0.1 0.0 0.1 1.9 18.2 293.6 0.2 0.0 0.3 0.0 0.0 3.2 0.9 0.1 0.1 2.6 0.4 0.0 0.0 0.0 3.7 0.1 0.0 2.8 0.0 0.0 0.0 0.0 83.1 2.1 0.5 5.4 0.0 0.0 3.1 0.0 0.5 0.7 2.6 0.0 0.4 0.0 0.4 0.0 23.3 0.0 0.1 0.0 0.0 0.1 15.0 1.7 0.0 0.0 0.0 0.3 0.0 0.1 0.8 PLA1A ps-PLA1 ENSG00000144837 "Phospholipase A1 member A" Q53H76 3 119597875-119629811 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 138.4;parathyroid gland: 65.8;seminal vesicle: 67.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 14.7;Endothelial cells: 14.3;Hepatocytes: 26.0;Langerhans cells: 15.6;Peritubular cells: 14.3" "Group enriched" "Detected in many" 5 "liver cancer: 14.8;melanoma: 55.4;prostate cancer: 24.2;renal cancer: 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "SK-MEL-30: 25.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059740 Approved "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" "Secreted in other tissues" NA NA 420000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytoplasmic bodies" Nucleoplasm "HPA059740: AB_2684118" "unprognostic (1.35e-1)" "prognostic favorable (2.81e-7)" "unprognostic (2.24e-2)" "unprognostic (3.46e-2)" "unprognostic (3.18e-2)" "unprognostic (1.94e-2)" "unprognostic (1.11e-2)" "unprognostic (2.43e-1)" "unprognostic (3.87e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" "unprognostic (9.09e-2)" "unprognostic (1.55e-3)" "unprognostic (9.53e-3)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" "unprognostic (2.67e-1)" 4.9 0.7 12.1 3.5 11.3 0.3 3.4 11.6 16.3 4.7 26.8 2.7 1.1 4.7 138.4 1.5 5.7 2.8 4.9 12.5 12.0 7.7 39.6 21.2 15.6 13.2 12.3 1.1 3.7 65.8 1.7 9.8 13.2 9.1 2.5 1.0 3.5 67.2 16.2 0.8 3.5 8.8 13.4 1.0 4.4 3.7 14.7 1.6 6.9 3.1 8.7 3.9 1.9 12.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.8 0.3 0.5 0.1 0.0 0.2 0.0 0.0 25.0 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 12.1 11.3 11.6 16.3 12.5 12.0 13.2 12.3 13.2 13.4 14.7 12.4 6.5 0.0 1.7 0.0 0.0 0.6 0.5 0.4 0.6 0.0 0.1 0.1 2.8 2.8 1.0 14.7 0.0 0.2 0.1 0.0 1.9 4.7 6.6 0.1 0.1 14.3 1.8 0.0 0.2 2.2 0.0 1.6 0.0 0.9 1.3 0.7 7.9 26.0 1.6 0.0 0.1 0.1 0.0 1.0 15.6 3.2 0.3 5.4 1.8 4.7 4.2 0.0 0.0 0.0 0.0 1.3 0.6 14.3 0.0 0.5 0.0 5.1 7.5 0.1 0.0 0.9 5.9 0.0 0.2 0.0 0.6 1.9 0.1 0.0 0.1 0.2 PLA2G10 GXPLA2 ENSG00000069764 "Phospholipase A2 group X" O15496 16 14672548-14694308 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 27.3;pancreas: 10.5;stomach 1: 41.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 280.1;Exocrine glandular cells: 116.3;Gastric mucus-secreting cells: 116.2;Intestinal goblet cells: 137.7;Paneth cells: 225.3" "Cancer enhanced" "Detected in many" "stomach cancer: 6.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.6;CAPAN-2: 6.4;HaCaT: 2.2;MCF7: 2.3;OE19: 5.9;SK-BR-3: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA041893 Uncertain "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041893: AB_10794495" "unprognostic (8.44e-3)" "unprognostic (2.37e-1)" "unprognostic (6.72e-2)" "prognostic favorable (5.74e-5)" "unprognostic (1.62e-2)" "unprognostic (3.16e-2)" "unprognostic (5.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.77e-2)" "unprognostic (2.72e-1)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (2.12e-1)" "unprognostic (4.08e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-2)" "unprognostic (9.97e-3)" 0.0 0.2 0.1 2.4 0.1 0.1 0.1 0.1 0.2 1.3 0.1 27.3 7.6 0.1 0.0 0.2 4.5 3.4 0.0 0.1 0.1 0.1 0.0 4.7 0.2 0.1 0.1 0.0 10.5 0.0 0.0 0.3 0.1 0.4 23.6 0.0 0.1 0.0 0.0 0.0 7.0 0.6 0.1 0.0 41.9 2.2 0.1 0.0 0.0 0.0 0.3 4.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.5 6.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.0 5.9 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.0 3.4 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 35.3 23.1 0.7 0.3 0.0 0.9 3.7 0.6 0.0 0.7 0.5 0.1 5.7 17.9 1.8 0.0 0.6 0.1 280.1 0.0 2.6 0.3 25.1 3.5 0.2 12.7 0.0 0.5 116.3 56.7 0.1 116.2 45.7 0.0 0.4 0.0 0.0 0.9 0.0 0.3 137.7 24.4 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 20.5 225.3 0.0 0.7 1.3 16.1 0.0 60.1 0.0 0.0 0.0 2.0 1.1 1.2 1.7 0.0 0.5 0.5 0.0 57.3 14.6 PLA2G12A PLA2G12 ENSG00000123739 "Phospholipase A2 group XIIA" Q9BZM1 4 109709989-109730070 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035908, HPA035909" Approved "Secreted to blood" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 51: Myeloid cells - Hemostasis" "HPA035908: AB_2674856, HPA035909: AB_10672074" "unprognostic (8.40e-2)" "unprognostic (3.87e-1)" "unprognostic (3.81e-3)" "unprognostic (3.09e-2)" "unprognostic (2.10e-1)" "unprognostic (1.35e-1)" "unprognostic (4.26e-2)" "unprognostic (1.77e-1)" "unprognostic (1.90e-1)" "unprognostic (2.71e-3)" "unprognostic (1.02e-1)" "unprognostic (8.42e-2)" "prognostic favorable (2.54e-9)" "unprognostic (3.10e-1)" "unprognostic (1.39e-1)" "unprognostic (9.16e-3)" "unprognostic (3.64e-2)" 10.0 9.0 11.4 3.4 12.7 6.2 12.0 12.6 13.8 8.4 11.9 11.5 10.5 8.1 7.3 11.4 8.4 7.3 16.0 10.4 12.2 14.7 21.2 7.4 4.0 13.9 14.4 10.5 34.5 23.0 12.5 3.7 13.1 15.1 10.8 15.5 11.8 7.1 22.1 9.3 10.6 7.0 14.2 5.2 9.8 5.0 12.7 4.9 17.8 19.3 4.6 7.0 7.6 15.1 17.2 6.2 4.8 7.4 15.0 14.9 9.4 14.9 11.0 8.5 8.9 15.6 29.1 24.5 11.6 11.1 14.0 9.3 14.9 20.1 13.0 8.3 22.8 8.7 17.5 11.5 14.2 19.2 5.9 15.1 22.9 8.6 21.3 14.3 7.7 22.5 48.8 10.7 14.7 30.3 15.7 8.6 8.6 39.0 24.1 9.3 14.3 19.5 16.2 25.0 30.8 10.1 13.7 35.5 11.9 12.3 21.3 4.0 10.4 12.4 10.1 12.9 10.8 18.5 36.0 17.8 13.5 11.0 15.5 5.4 4.1 2.7 6.2 2.7 5.7 3.7 7.8 6.0 8.2 4.3 8.7 8.0 1.8 5.0 4.5 7.0 8.3 12.1 11.4 12.7 12.6 13.8 10.4 12.2 13.9 14.4 13.1 14.2 12.7 15.1 11.7 25.6 21.8 14.4 11.7 36.7 36.3 39.7 25.0 52.5 27.5 18.3 56.8 30.0 24.9 22.0 50.1 42.7 8.3 31.5 27.4 15.0 26.7 15.1 9.5 17.1 107.7 48.4 24.1 25.9 53.4 29.3 32.6 14.0 14.0 147.4 23.9 103.1 19.4 26.9 28.6 52.8 34.6 22.4 17.1 8.7 33.2 64.6 30.2 18.7 6.1 47.7 13.4 16.6 20.1 13.9 38.9 34.6 20.6 67.8 78.9 19.2 16.4 42.3 19.7 38.2 21.1 62.7 47.5 39.0 42.6 34.5 14.3 28.6 58.9 44.9 PLA2G12B PLA2G13 ENSG00000138308 "Phospholipase A2 group XIIB" Q9BX93 10 72934762-72954806 "Metabolic proteins, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 33.1;kidney: 14.4;liver: 71.0" "Group enriched" "Detected in some" 4 "Hepatocytes: 52.2;Proximal enterocytes: 70.0" "Cancer enriched" "Detected in many" 8 "liver cancer: 35.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "CACO-2: 9.1;Hep G2: 15.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA057745, HPA059562" Approved "Secreted to blood" NA NA 2300000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "HPA057745: AB_2683514, HPA059562: AB_2684064" "unprognostic (1.11e-2)" "unprognostic (2.66e-2)" "unprognostic (2.02e-3)" "unprognostic (3.41e-1)" "unprognostic (1.68e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-1)" "unprognostic (3.14e-2)" 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.0 0.0 2.2 27.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 14.4 71.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.0 0.0 0.0 33.1 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.3 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 3.1 1.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.8 52.2 0.0 0.0 0.3 2.4 0.0 0.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.0 70.0 13.4 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 6.3 0.0 PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 58.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 116.0;Horizontal cells: 38.7;Kupffer cells: 37.1;Syncytiotrophoblasts: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (3.47e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-3)" "unprognostic (6.84e-3)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.12e-3)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.84e-2)" "unprognostic (2.56e-1)" "unprognostic (9.29e-2)" "unprognostic (2.45e-3)" "unprognostic (2.98e-2)" "unprognostic (5.40e-3)" "unprognostic (6.28e-2)" "unprognostic (3.47e-2)" 15.1 11.5 12.9 7.6 12.5 7.0 9.8 12.8 18.1 6.6 9.2 8.0 6.9 6.2 8.7 6.2 7.4 9.3 35.5 13.1 14.2 33.4 17.3 17.5 13.6 13.1 14.1 7.7 7.4 11.4 11.4 27.3 14.6 8.1 5.9 4.4 9.1 5.7 58.3 13.9 6.5 8.8 12.4 20.3 8.4 10.8 15.9 11.7 13.2 22.4 5.1 8.8 6.4 16.1 10.0 10.0 7.9 25.5 36.7 26.8 19.0 24.6 31.6 35.7 30.2 26.1 18.6 17.4 31.2 34.1 28.5 15.2 8.5 10.4 15.9 6.0 16.4 5.0 10.4 19.0 19.6 4.6 25.0 19.0 11.2 35.2 5.5 44.6 22.5 8.9 7.9 9.8 23.0 21.3 7.2 14.5 5.1 9.4 12.1 9.9 11.3 55.3 17.7 8.7 3.0 5.1 31.2 9.6 19.2 6.6 25.2 23.7 18.8 31.5 15.0 41.1 16.5 34.6 33.5 22.1 28.6 13.8 12.0 19.6 24.1 16.0 4.7 27.5 4.8 5.0 5.2 7.0 14.1 5.3 6.5 5.5 1.0 2.3 32.4 12.2 5.1 14.6 12.9 12.5 12.8 18.1 13.1 14.2 13.1 14.1 14.6 12.4 15.9 16.1 4.4 6.4 3.3 3.6 3.0 4.8 2.4 6.8 2.8 12.1 7.0 6.0 22.5 1.5 5.1 9.2 8.4 20.9 4.9 8.1 5.9 10.1 1.9 4.3 4.8 5.9 0.0 1.7 7.0 7.2 7.6 8.2 8.6 9.0 15.2 6.6 9.3 13.7 116.0 38.7 6.7 8.5 2.0 37.1 6.8 6.1 2.1 21.4 12.4 10.3 7.7 4.4 3.1 5.5 3.9 6.3 5.0 1.5 2.6 2.6 3.0 19.5 2.7 6.1 0.0 5.5 6.7 3.4 2.8 4.1 3.4 50.8 3.9 3.1 4.1 2.0 PLA2G1B "PLA2, PLA2A, PPLA2" ENSG00000170890 "Phospholipase A2 group IB" P04054 12 120322115-120327779 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1519 "pancreas: 117705.6" "Cell type enriched" "Detected in many" 17 "Exocrine glandular cells: 20351.4" "Cancer enriched" "Detected in many" 185 "pancreatic cancer: 763.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;U-2 OS: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047822, HPA060803" Enhanced "Secreted to digestive system" NA NA 3900000 "Cluster 48: NK-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" "HPA047822: AB_2680169, HPA060803: AB_2684369" "unprognostic (1.28e-4)" "unprognostic (6.02e-2)" "unprognostic (1.84e-2)" "unprognostic (2.86e-2)" "unprognostic (2.74e-2)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (3.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (2.80e-4)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (3.60e-1)" "unprognostic (8.61e-4)" 10.0 6.5 0.2 1.7 0.1 2.9 5.8 0.2 0.6 5.8 0.0 2.3 15.8 2.3 0.0 3.3 1.8 0.9 21.5 0.2 0.2 2.7 7.2 32.1 4.0 0.1 0.1 77.5 117705.6 0.0 4.4 6.0 0.2 4.4 0.3 0.7 21.3 0.0 1.9 3.4 7.7 0.1 0.1 3.0 8.7 4.3 0.1 0.3 1.5 0.0 0.0 1.3 1.9 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 1.9 0.2 0.2 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.6 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.0 12.8 91.5 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.8 1.3 0.4 0.0 0.8 0.0 0.0 0.0 0.2 0.2 1.9 24.3 10.6 0.4 0.1 1.1 1.2 0.0 0.1 20351.4 0.0 0.3 0.0 0.0 0.0 8.6 0.0 1.9 0.0 0.0 0.1 1.2 0.0 0.0 0.0 41.0 3.1 1.5 0.0 1.0 43.9 0.0 2.1 0.0 0.0 1142.1 1.7 3.4 0.1 0.2 4.1 7.6 1.0 0.0 0.0 0.0 3.4 0.5 0.2 0.0 0.1 0.0 0.3 12.5 1.2 0.1 PLA2G2C UBXN10-AS1 ENSG00000187980 "Phospholipase A2 group IIC" Q5R387 1 20161253-20186518 "Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "intestine: 1.2" "Group enriched" "Detected in some" 4 "Early spermatids: 2.9;Late spermatids: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 1.6;U-698: 2.0;U-937: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.02e-3)" "unprognostic (2.75e-2)" "unprognostic (5.76e-2)" "unprognostic (3.00e-4)" "unprognostic (9.44e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (1.32e-1)" "unprognostic (3.92e-1)" "unprognostic (1.80e-1)" "unprognostic (1.46e-1)" "unprognostic (1.22e-2)" "unprognostic (4.84e-2)" "unprognostic (1.67e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (8.16e-2)" 0.1 0.0 0.4 0.1 0.2 0.4 0.0 0.7 0.5 0.1 0.3 1.2 0.2 0.4 0.2 0.7 0.1 0.1 0.1 0.5 0.3 0.0 0.0 0.1 0.2 0.3 0.3 0.2 0.0 0.1 0.0 0.1 0.2 0.4 0.3 0.2 0.1 0.2 0.2 0.3 0.2 0.2 0.2 0.1 0.2 0.4 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.2 0.9 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.0 0.1 1.7 0.0 0.5 0.3 0.0 0.4 0.1 0.8 0.1 0.3 0.4 0.5 0.1 0.2 0.1 0.6 0.3 0.0 0.2 0.0 0.1 0.4 0.2 0.7 0.5 0.5 0.3 0.3 0.3 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 1.3 0.1 0.0 0.0 1.1 0.0 0.1 0.2 0.0 0.6 0.0 9.8 0.3 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 PLA2G2D sPLA2S ENSG00000117215 "Phospholipase A2 group IID" Q9UNK4 1 20111939-20119566 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 106.4" "Cell type enhanced" "Detected in some" "B-cells: 1.6;dendritic cells: 1.3;Kupffer cells: 2.4;Melanocytes: 5.4;Plasma cells: 8.1" "Cancer enriched" "Detected in many" 6 "testis cancer: 25.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory B-cell: 3.7;naive B-cell: 3.6;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 6 "B-cells: 3.7;dendritic cells: 2.0" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (4.35e-4)" "prognostic favorable (8.15e-5)" "unprognostic (3.88e-3)" "prognostic favorable (9.74e-4)" "unprognostic (1.78e-1)" "unprognostic (2.56e-3)" "unprognostic (1.98e-1)" "unprognostic (1.60e-2)" "unprognostic (1.82e-5)" "unprognostic (7.51e-4)" "unprognostic (2.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.85e-1)" "unprognostic (8.08e-2)" "unprognostic (2.60e-1)" 0.7 0.1 0.1 15.8 0.1 0.8 0.9 0.3 0.2 0.3 0.0 2.3 1.4 0.4 0.1 0.4 0.4 1.7 0.2 0.1 0.0 0.1 0.7 2.4 106.4 0.1 0.0 1.0 0.3 0.0 0.0 0.1 0.1 0.4 3.3 0.1 1.2 0.4 0.0 0.2 4.5 0.2 0.0 11.0 2.3 0.4 0.1 3.1 0.3 0.0 59.1 4.5 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.2 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.4 0.4 0.0 0.0 0.6 5.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 PLA2G3 GIII-SPLA2 ENSG00000100078 "Phospholipase A2 group III" Q9NZ20 22 31134807-31140508 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Cilium biogenesis/degradation, Lipid metabolism, Mast cell degranulation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 5.9;esophagus: 13.8;skin 1: 15.4;vagina: 7.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.6;Breast glandular cells: 7.5;Suprabasal keratinocytes: 17.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 15.1;AN3-CA: 15.3;NTERA-2: 7.8;SCLC-21H: 11.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA021016 Uncertain Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Endoplasmic reticulum" "HPA021016: AB_1855443" "unprognostic (1.80e-1)" "unprognostic (4.63e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "prognostic favorable (4.47e-4)" "unprognostic (1.74e-2)" "unprognostic (2.30e-1)" "unprognostic (4.25e-2)" "unprognostic (9.55e-3)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.29e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 1.2 0.8 0.2 5.9 0.7 0.1 0.3 0.0 0.0 13.8 0.0 0.0 0.0 0.4 0.1 0.5 0.0 2.5 0.0 1.6 0.1 0.0 0.0 1.0 0.1 0.0 1.7 0.3 0.0 0.0 1.8 0.3 0.2 15.4 0.2 0.0 0.1 0.0 0.6 0.5 0.1 0.1 0.6 0.0 1.7 0.0 7.1 0.2 0.0 0.0 15.1 15.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.4 0.1 1.6 0.1 1.7 0.1 0.1 0.2 0.0 0.0 3.6 1.6 0.0 1.3 0.2 0.2 0.0 0.0 7.5 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 17.8 0.0 0.0 0.0 0.0 0.4 PLA2G7 "LDL-PLA2, PAFAH" ENSG00000146070 "Phospholipase A2 group VII" Q13093 6 46704201-46735693 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Asthma, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.2;placenta: 23.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 372.2;Macrophages: 140.9" "Cancer enhanced" "Detected in all" "prostate cancer: 37.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 43.4" "Group enriched" "Detected in many" 49 "dendritic cells: 14.1;monocytes: 43.4" "Cell line enhanced" "Detected in some" "NTERA-2: 1.7;PC-3: 3.4;RT4: 1.6;U-2 OS: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 7380000 290000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.63e-3)" "unprognostic (2.82e-3)" "unprognostic (8.69e-2)" "unprognostic (3.00e-1)" "unprognostic (1.47e-1)" "unprognostic (6.26e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-2)" "unprognostic (5.33e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "unprognostic (9.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" 4.5 3.1 1.6 22.9 3.6 2.8 2.6 2.7 4.5 2.5 0.4 7.5 4.1 4.8 1.1 0.6 1.9 6.0 0.6 2.6 1.4 0.3 6.9 7.2 26.8 3.9 2.6 1.1 0.8 21.0 2.1 23.3 4.2 13.1 10.3 0.6 1.4 2.6 0.4 3.6 3.3 2.8 2.6 27.2 2.9 0.9 8.9 4.9 20.2 0.0 10.0 11.1 0.3 7.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.9 0.7 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 3.4 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.4 0.4 0.4 0.0 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.3 43.4 0.3 0.1 9.2 0.3 0.3 0.0 0.0 14.1 0.0 0.0 0.1 0.5 0.0 0.5 0.3 0.0 11.9 1.6 3.6 2.7 4.5 2.6 1.4 3.9 2.6 4.2 2.6 8.9 7.4 0.5 0.0 1.3 0.3 3.6 0.8 4.4 0.0 0.0 0.2 0.3 4.3 0.3 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.6 0.1 1.6 50.3 0.6 3.5 0.0 7.1 0.0 5.1 1.8 0.0 1.5 0.0 0.0 0.0 0.0 372.2 1.7 4.8 0.3 0.0 24.6 4.9 0.1 0.0 140.9 10.6 11.2 29.3 0.3 0.0 6.0 0.3 0.3 0.0 0.0 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.9 0.6 0.1 0.0 0.1 0.1 3.1 0.8 8.9 0.2 3.8 PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 39.1;thyroid gland: 41.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Excitatory neurons: 34.6;Inhibitory neurons: 43.5;Muller glia cells: 33.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 14.5;ASC TERT1: 19.5;BJ hTERT+: 16.2;hTERT-RPE1: 26.3;TIME: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" NA NA 960000 "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "CAB068217: AB_2665660, CAB068218: AB_2665661" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (4.91e-3)" "unprognostic (6.01e-2)" "unprognostic (9.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (9.38e-3)" "unprognostic (4.30e-3)" "unprognostic (2.82e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.62e-1)" "unprognostic (6.58e-2)" "unprognostic (2.02e-1)" 4.7 2.9 0.7 1.4 0.8 0.0 14.9 9.7 2.2 6.9 1.7 3.1 3.9 8.8 2.9 4.7 5.4 9.3 2.5 0.5 1.5 20.8 1.4 2.6 1.9 2.0 2.7 10.8 0.6 19.7 2.2 3.8 2.1 3.1 3.2 5.6 39.1 2.9 0.5 10.9 6.1 6.9 1.4 5.1 1.6 1.0 2.5 0.6 41.9 1.3 2.7 3.9 6.0 1.0 0.2 1.6 0.6 0.0 14.5 19.5 0.1 6.8 16.2 1.3 1.8 0.0 3.4 0.0 0.4 7.2 1.4 3.3 0.1 5.0 1.4 0.0 0.0 0.0 11.8 0.0 1.2 0.0 0.0 7.9 5.4 1.9 2.1 26.3 9.3 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.2 0.1 2.6 0.0 0.0 0.0 1.4 0.7 0.0 0.0 11.8 2.2 0.0 1.7 2.6 0.2 47.3 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.8 9.7 2.2 0.5 1.5 2.0 2.7 2.1 1.4 2.5 1.0 11.1 6.4 2.8 20.9 0.1 9.4 2.7 18.1 21.6 2.7 22.1 14.5 4.1 5.7 11.3 33.1 0.0 7.3 0.5 1.7 0.0 0.6 0.1 5.6 22.0 4.0 1.2 0.0 34.6 2.0 1.3 14.8 0.0 9.4 1.3 9.6 8.6 0.0 0.6 16.8 43.5 7.2 4.1 0.0 2.1 1.4 16.1 0.5 7.2 25.3 0.0 33.5 0.0 5.5 1.8 5.1 11.3 16.6 0.1 2.6 15.6 2.3 8.1 1.4 6.6 3.4 4.8 0.1 1.0 9.3 5.4 1.5 0.6 6.3 7.5 3.0 PLAC1 "CT92, OOSP2B, OOSP2L" ENSG00000170965 "Placenta enriched 1" Q9HBJ0 X 134565838-134764322 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 29 "placenta: 27.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 24.5;Leydig cells: 5.6;Peritubular cells: 7.9;Spermatocytes: 6.5;Spermatogonia: 11.0;Syncytiotrophoblasts: 10.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 20.1;hTCEpi: 15.6;hTERT-HME1: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000163, HPA063425" Enhanced Approved Vesicles,Cytosol "Secreted in female reproductive system" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Vesicles Cytosol "HPA000163: , HPA063425: AB_2685012" "unprognostic (2.93e-1)" "unprognostic (2.50e-3)" "unprognostic (2.89e-4)" "unprognostic (1.35e-7)" "unprognostic (3.83e-3)" "unprognostic (2.07e-2)" "unprognostic (1.63e-2)" "unprognostic (1.26e-1)" "unprognostic (2.01e-1)" "unprognostic (4.28e-2)" "unprognostic (1.48e-2)" "unprognostic (2.87e-2)" "unprognostic (3.33e-16)" "unprognostic (7.64e-3)" "unprognostic (4.03e-2)" "unprognostic (1.61e-1)" "unprognostic (1.91e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.9 0.0 1.2 0.0 0.2 1.2 0.3 0.4 1.1 0.0 2.0 0.3 0.1 1.8 0.3 0.5 20.1 0.0 0.1 0.3 2.3 0.0 0.0 0.9 15.6 0.1 6.3 0.1 2.4 0.2 0.1 1.7 0.1 1.0 0.0 0.3 0.0 1.3 2.6 0.0 0.3 3.7 0.0 0.0 3.0 0.0 0.0 3.7 0.7 2.2 0.1 0.0 0.0 0.5 0.8 0.2 0.0 0.4 0.1 0.3 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 1.3 0.0 2.8 24.5 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.9 0.0 0.0 0.0 0.0 0.7 5.6 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.5 0.1 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 11.0 0.0 0.0 10.7 0.0 2.1 0.0 0.0 PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 124.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 926.5;Leydig cells: 873.5;Peritubular cells: 659.7;Sertoli cells: 295.9;Smooth muscle cells: 446.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 98.5;ASC TERT1: 85.3;BEWO: 32.1;HSkMC: 28.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 37.9" HPA043469 Uncertain "Secreted - unknown location" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043469: AB_10795770" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (1.78e-2)" "unprognostic (2.76e-1)" "unprognostic (3.93e-1)" "unprognostic (5.57e-3)" "unprognostic (5.88e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-3)" 112.3 18.4 10.2 6.6 9.2 1.2 85.7 10.3 15.5 77.3 53.3 22.1 4.0 26.9 5.0 21.4 30.4 9.0 124.3 14.3 5.9 17.9 6.4 56.1 2.7 5.9 5.8 11.5 5.7 4.1 4.9 12.5 6.4 35.9 4.6 0.6 20.1 7.6 16.9 47.8 19.7 6.5 6.5 5.0 21.4 14.9 6.9 2.2 44.6 19.2 1.9 54.0 75.7 8.5 0.2 0.0 0.8 0.0 98.5 85.3 32.1 10.3 8.7 0.9 1.2 0.0 0.7 0.0 0.2 6.0 0.1 0.8 0.1 0.0 0.0 0.8 0.3 0.0 0.5 0.0 16.4 0.0 2.3 28.7 0.0 2.1 1.2 10.6 3.4 0.4 0.0 0.4 0.0 0.3 0.1 0.6 1.9 0.4 1.5 0.0 0.1 1.5 0.0 0.6 0.0 1.8 0.0 1.2 0.7 0.2 0.1 0.2 3.6 6.6 3.6 21.0 0.2 0.7 0.9 0.1 1.9 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 10.2 9.2 10.3 15.5 14.3 5.9 5.9 5.8 6.4 6.5 6.9 8.5 246.2 3.2 1.8 0.0 1.6 126.4 0.7 1.1 8.0 0.4 7.4 14.0 24.4 0.0 0.3 0.0 0.0 7.0 3.6 0.1 0.0 0.3 4.6 3.1 75.7 102.5 1.8 0.0 0.5 0.2 17.7 926.5 5.6 4.4 1.3 0.1 115.6 0.3 14.1 0.0 0.5 0.0 0.0 0.0 191.3 26.7 873.5 7.9 136.9 7.5 0.0 50.2 0.0 0.0 0.2 0.7 0.0 659.7 2.1 1.0 0.0 0.2 0.9 1.7 295.9 89.7 446.6 2.6 2.9 4.6 126.3 11.5 14.1 1.1 0.0 1.8 PLAGL1 "LOT1, ZAC" ENSG00000118495 "PLAG1 like zinc finger 1" Q9UM63 6 143940300-144064599 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 252.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 143.6;Leydig cells: 138.5;Theca cells: 205.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 99.0;RH-30: 94.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055706 Supported "Nuclear bodies,Golgi apparatus,Vesicles" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" "Nuclear bodies" "Golgi apparatus, Vesicles" "HPA055706: AB_2682893" "unprognostic (4.74e-3)" "unprognostic (8.35e-3)" "unprognostic (5.43e-2)" "unprognostic (1.74e-3)" "unprognostic (5.09e-2)" "unprognostic (1.95e-1)" "unprognostic (9.32e-2)" "unprognostic (6.17e-2)" "unprognostic (3.49e-2)" "unprognostic (5.02e-2)" "unprognostic (1.78e-3)" "unprognostic (2.07e-1)" "prognostic unfavorable (4.94e-6)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.69e-2)" "unprognostic (5.17e-3)" "unprognostic (4.93e-3)" 37.7 74.8 4.1 18.5 5.2 21.7 29.6 1.9 7.0 31.4 5.8 28.8 9.6 29.5 9.0 32.9 20.8 26.9 26.4 3.8 2.9 17.0 3.6 26.7 12.1 3.6 4.1 36.5 27.7 9.5 81.6 252.3 3.9 26.0 21.3 1.6 30.1 12.1 12.2 61.9 20.6 19.7 3.2 15.6 26.9 8.7 6.0 6.6 13.8 22.3 12.1 39.6 34.4 4.0 0.2 5.0 99.0 0.1 39.4 78.0 0.3 32.9 21.6 16.1 33.5 0.3 6.0 2.7 16.0 30.4 4.0 0.0 0.8 12.0 32.2 3.1 4.4 45.2 58.7 0.9 13.9 40.9 8.9 60.5 4.6 15.8 13.8 23.4 33.5 16.1 4.4 0.8 18.0 6.2 16.9 19.8 17.2 0.0 3.7 20.7 94.1 0.1 33.1 1.1 8.7 10.3 51.0 0.1 0.1 29.6 0.1 50.1 19.8 0.2 35.2 77.7 36.4 9.1 9.0 0.6 25.3 16.6 2.0 4.9 12.0 25.1 1.4 9.1 1.4 3.7 1.3 1.9 14.9 5.8 0.9 1.5 21.7 2.2 2.9 6.7 2.0 3.8 4.1 5.2 1.9 7.0 3.8 2.9 3.6 4.1 3.9 3.2 6.0 4.0 19.5 51.3 51.0 28.4 15.2 21.7 14.6 5.3 34.1 2.1 16.8 14.0 8.4 5.7 12.6 5.5 0.0 4.6 19.0 16.1 7.9 11.8 1.8 8.6 91.9 23.8 16.7 19.3 60.3 11.3 15.0 143.6 11.7 13.0 18.4 38.7 8.6 0.2 20.3 8.4 76.6 33.6 18.3 26.8 27.8 5.5 138.5 26.8 8.8 49.6 37.6 0.9 2.1 10.6 5.5 13.0 22.5 97.0 5.7 52.0 4.3 15.3 4.4 0.4 13.1 61.7 31.1 0.9 1.0 24.1 43.3 9.9 10.0 205.8 28.5 19.7 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42174718-42207709 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 246.0;urinary bladder: 181.4" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 763.3;Urothelial cells: 992.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 604.7;HMC-1: 425.2;hTERT-RPE1: 344.9;LHCN-M2: 298.2;U-2197: 441.2;WM-115: 806.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" NA NA 9900000 110000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favorable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 58.9 44.0 14.0 35.6 13.7 0.1 35.1 14.6 17.4 21.8 10.3 55.3 29.9 49.6 16.8 33.7 49.8 40.4 19.3 12.5 16.6 91.9 5.3 41.3 2.3 15.4 15.4 21.5 16.0 246.0 13.3 44.4 16.6 54.0 25.0 2.1 15.6 29.1 8.8 6.2 34.6 32.9 16.0 2.0 41.8 11.9 18.8 4.4 30.9 9.8 2.7 181.4 33.1 14.0 4.2 1.4 29.0 9.1 43.1 61.9 0.9 125.8 216.4 54.2 43.4 1.4 604.7 0.0 4.4 17.1 28.4 14.5 0.3 23.9 78.5 64.6 8.4 0.7 1.0 0.6 253.9 0.2 425.2 65.6 0.4 140.3 6.0 344.9 103.9 0.2 4.6 0.8 298.2 0.0 0.6 0.5 42.3 0.3 48.2 0.2 103.5 0.3 12.6 0.4 0.3 7.4 0.2 0.4 158.7 39.7 1.0 0.3 189.3 11.6 43.1 441.2 15.6 0.2 1.1 0.2 9.7 0.2 806.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.0 13.7 14.6 17.4 12.5 16.6 15.4 15.4 16.6 16.0 18.8 14.0 63.5 0.0 13.7 0.0 2.9 10.8 763.3 155.9 7.4 4.7 103.9 66.3 7.4 1.5 19.1 0.0 4.2 0.6 0.9 0.1 0.0 9.3 0.9 4.8 104.2 98.2 0.0 0.0 1.6 0.6 1.3 136.5 2.0 5.1 164.0 89.7 36.4 0.8 1.9 1.7 4.0 0.0 4.1 1.0 17.7 1.5 3.7 4.7 23.2 25.3 1.6 2.1 1.0 42.7 0.3 52.0 0.0 2.6 2.8 193.3 0.2 0.3 4.0 3.8 13.1 10.8 48.3 1.1 0.6 13.6 13.5 0.7 6.0 0.5 0.5 992.1 PLAU "UPA, URK" ENSG00000122861 "Plasminogen activator, urokinase" P00749 10 73909177-73917496 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 103.8;urinary bladder: 128.5" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 635.9;Basal respiratory cells: 237.3;Pancreatic endocrine cells: 613.9;Prostatic glandular cells: 695.0;Urothelial cells: 869.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "myeloid DC: 1.1;neutrophil: 2.1;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 11 "dendritic cells: 2.0;granulocytes: 2.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 856.0;LHCN-M2: 822.4;RPTEC TERT1: 3100.7;U-251 MG: 869.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA070796 Supported Uncertain "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 647000 88000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus, Vesicles" "HPA070796: " "unprognostic (1.96e-2)" "unprognostic (2.99e-2)" "unprognostic (7.40e-2)" "prognostic favorable (3.38e-4)" "unprognostic (4.73e-2)" "prognostic unfavorable (2.70e-4)" "unprognostic (1.39e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.26e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.83e-1)" "unprognostic (3.37e-2)" "unprognostic (1.51e-2)" "unprognostic (1.77e-2)" 57.6 4.8 2.5 41.7 2.7 36.2 17.6 2.7 8.9 9.3 4.4 13.1 11.9 22.0 16.7 14.4 10.3 28.5 23.1 2.4 2.9 103.8 5.0 22.0 14.3 3.8 2.9 2.3 10.1 8.3 2.9 36.5 5.4 9.1 18.2 0.3 17.3 13.7 10.8 25.5 13.7 23.4 3.3 40.6 15.7 3.7 4.7 5.9 17.9 18.9 7.2 128.5 16.2 4.7 171.1 88.9 36.8 1.7 3.1 59.5 2.0 101.9 461.6 40.0 62.2 2.3 856.0 0.1 184.0 14.5 416.9 114.1 0.9 165.8 44.8 9.9 0.0 0.1 4.4 1.7 72.6 15.6 32.3 158.7 20.2 271.4 103.7 447.0 114.7 1.0 1.1 0.9 822.4 0.2 0.2 22.7 10.8 0.3 244.5 0.4 112.6 0.9 3100.7 130.6 0.1 0.2 0.3 4.0 2.4 25.4 1.2 22.9 300.6 3.5 20.3 21.6 869.8 0.2 1.3 1.6 216.0 25.5 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.1 0.0 0.0 2.0 0.0 0.1 2.5 2.7 2.7 8.9 2.4 2.9 3.8 2.9 5.4 3.3 4.7 4.7 29.0 3.2 4.6 0.3 1.4 37.3 635.9 237.3 19.9 0.0 3.0 24.4 2.5 0.0 103.6 29.5 0.0 28.0 1.6 0.6 68.4 62.7 0.5 50.7 22.2 46.4 3.5 0.0 0.2 21.3 21.7 69.7 0.0 68.9 31.1 0.1 3.9 0.0 39.8 0.0 0.3 0.1 140.4 4.0 33.1 1.3 2.5 53.4 7.2 4.7 23.8 0.0 0.0 0.5 0.2 613.9 0.3 0.0 0.5 695.0 0.0 1.4 35.4 0.0 6.6 27.6 65.2 0.0 0.2 60.6 29.5 17.5 4.7 0.6 1.7 869.6 PLAUR "CD87, UPAR, URKR" ENSG00000011422 "Plasminogen activator, urokinase receptor" Q03405 19 43646095-43670547 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "bone marrow: 688.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 820.7;Langerhans cells: 1833.9;Macrophages: 864.3;Urothelial cells: 2274.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1172.3" "Group enriched" "Detected in all" 4 "granulocytes: 1172.3;monocytes: 550.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 311.7;U-251 MG: 413.1;U-87 MG: 346.9;WM-115: 346.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050843, CAB073533" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA 4100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB073533: , HPA050843: AB_2681255" "unprognostic (9.28e-2)" "unprognostic (9.65e-3)" "unprognostic (1.39e-1)" "unprognostic (1.29e-3)" "unprognostic (3.59e-3)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "prognostic unfavorable (2.33e-5)" "unprognostic (8.08e-3)" "unprognostic (4.30e-2)" "unprognostic (2.29e-3)" "unprognostic (5.30e-2)" "prognostic unfavorable (7.83e-9)" "unprognostic (4.99e-2)" "unprognostic (1.66e-1)" "unprognostic (5.45e-2)" "unprognostic (9.33e-2)" 52.1 10.4 7.5 81.7 9.8 688.4 14.5 11.2 32.4 30.9 10.3 26.7 10.0 30.2 4.8 11.6 22.8 78.1 23.0 8.1 10.4 18.2 19.8 69.5 10.6 12.2 9.8 14.9 13.6 5.4 9.1 35.9 13.3 11.5 20.1 2.8 21.7 5.8 3.6 7.8 10.6 26.2 9.7 20.4 28.4 3.1 24.8 10.2 9.5 4.7 8.6 109.7 15.8 13.8 83.9 31.0 26.1 1.9 23.4 83.3 16.2 180.7 189.6 114.6 141.4 2.4 95.1 2.4 43.0 116.9 66.8 35.2 7.0 46.4 127.9 5.3 5.3 15.8 44.7 3.9 30.6 18.8 195.2 87.4 9.0 311.7 46.5 160.6 129.0 19.1 16.4 2.2 107.7 6.1 21.0 55.3 8.7 156.1 64.7 24.0 17.4 5.6 35.9 3.8 1.3 22.2 82.0 17.4 25.0 12.6 3.2 59.4 129.7 230.0 121.1 109.8 413.1 3.0 9.0 0.6 346.9 36.0 346.5 87.7 476.5 745.5 6.8 427.9 8.3 2.7 8.9 5.7 213.6 1.4 3.2 4.0 1172.3 6.7 550.7 69.3 3.6 253.9 7.5 9.8 11.2 32.4 8.1 10.4 12.2 9.8 13.3 9.7 24.8 13.8 23.1 73.7 76.6 2.3 15.5 105.2 820.7 274.2 72.3 0.7 45.8 22.5 4.5 24.3 151.9 20.2 0.0 6.5 17.4 314.5 1.9 219.3 0.9 188.1 68.0 64.9 14.8 5.2 2.5 106.5 58.8 145.4 156.0 519.1 305.2 4.2 19.2 1.7 428.9 10.1 3.3 85.3 22.4 155.4 1833.9 2.0 6.8 864.3 72.9 5.6 52.1 1.2 4.1 1.5 0.9 558.8 435.5 4.1 14.5 479.4 12.7 2.7 52.7 0.7 6.6 38.5 90.0 1.2 4.7 202.6 63.1 13.1 33.2 3.1 29.3 2274.4 PLBD1 FLJ22662 ENSG00000121316 "Phospholipase B domain containing 1" Q6P4A8 12 14503661-14567883 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 187.7;Hofbauer cells: 105.6;Kupffer cells: 109.4;Macrophages: 116.3;monocytes: 192.8;Paneth cells: 105.9" "Cancer enhanced" "Detected in all" "testis cancer: 113.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 662.9;intermediate monocyte: 204.4;myeloid DC: 357.3;neutrophil: 443.8" "Group enriched" "Detected in all" 135 "dendritic cells: 357.3;granulocytes: 443.8;monocytes: 662.9" "Cell line enhanced" "Detected in many" "AN3-CA: 48.6;BEWO: 98.4;CAPAN-2: 245.6;MCF7: 46.3" "Not detected" "Not detected" HPA040303 Enhanced "Intracellular and membrane" NA NA 3400000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA040303: AB_2676922" "unprognostic (9.13e-3)" "unprognostic (5.77e-2)" "unprognostic (2.29e-1)" "unprognostic (7.87e-2)" "unprognostic (1.71e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (4.80e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.12e-1)" "unprognostic (3.03e-3)" "unprognostic (3.47e-1)" "unprognostic (1.97e-1)" "unprognostic (4.99e-2)" "unprognostic (5.44e-2)" 29.4 5.6 2.1 33.7 2.5 285.9 27.8 2.4 3.7 22.4 25.9 58.8 28.2 13.5 10.6 56.3 16.6 33.1 32.6 2.1 2.4 26.3 10.6 64.0 9.2 3.5 3.2 4.4 30.0 3.2 3.4 35.9 3.2 10.2 79.2 0.8 11.9 15.3 9.9 24.8 42.6 28.1 3.1 25.2 36.6 10.0 2.8 7.8 6.1 17.2 32.7 58.5 29.6 4.8 7.1 5.0 0.5 48.6 0.3 0.0 98.4 0.2 0.0 3.0 2.4 14.1 245.6 0.0 1.4 1.0 0.4 9.4 0.0 0.0 0.5 0.0 0.1 0.0 6.4 0.0 3.8 0.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 21.2 0.0 1.1 46.3 0.1 0.2 16.5 0.7 0.3 0.1 0.1 0.5 0.7 28.9 0.0 0.4 30.2 14.8 1.9 26.5 9.0 9.6 0.0 0.5 0.4 0.0 0.6 8.7 23.7 0.2 0.0 0.1 0.4 0.4 662.9 5.8 1.0 204.4 0.6 3.6 0.5 0.4 357.3 0.8 0.7 0.7 443.8 1.7 73.5 4.1 0.9 423.2 2.1 2.5 2.4 3.7 2.1 2.4 3.5 3.2 3.2 3.1 2.8 4.8 15.5 9.6 8.6 0.3 2.9 6.8 8.8 4.9 6.8 0.0 11.9 6.6 16.5 30.0 20.4 33.1 0.0 94.5 1.5 67.8 11.7 13.1 51.8 2.5 9.1 7.2 9.1 1.7 1.6 46.5 187.7 59.6 13.3 0.9 5.1 5.9 4.6 2.9 105.6 0.0 0.9 31.3 6.1 109.4 68.6 5.8 26.1 116.3 5.4 7.5 192.8 1.6 1.0 1.5 0.2 28.6 105.9 27.8 3.6 3.8 52.8 15.7 19.0 0.2 0.0 12.0 10.4 17.4 12.0 17.8 19.9 70.3 1.6 6.1 75.2 30.1 PLBD2 p76 ENSG00000151176 "Phospholipase B domain containing 2" Q8NHP8 12 113358566-113391629 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 139.0" "Group enriched" "Detected in many" 5 "Early spermatids: 139.8;Late spermatids: 398.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 246.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017163 Approved "Intracellular and membrane" NA NA 820000 "Cluster 39: Non-specific - mRNA processing" "Cluster 43: Testis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA017163: AB_1853029" "unprognostic (8.28e-2)" "unprognostic (1.97e-1)" "unprognostic (1.50e-2)" "unprognostic (4.13e-1)" "unprognostic (2.36e-3)" "unprognostic (7.59e-3)" "unprognostic (5.92e-3)" "unprognostic (2.39e-2)" "unprognostic (2.35e-1)" "unprognostic (3.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.58e-11)" "unprognostic (7.55e-3)" "unprognostic (5.88e-2)" "unprognostic (1.09e-1)" "unprognostic (5.48e-2)" 26.7 139.0 23.6 16.7 21.3 9.0 16.4 31.0 30.3 20.5 5.7 12.9 8.1 19.7 25.9 12.6 13.9 20.2 31.7 23.2 33.4 11.8 23.3 20.9 10.8 47.4 35.2 48.6 26.1 17.5 27.2 12.8 44.7 17.9 12.8 13.0 17.9 15.9 23.8 19.1 11.4 27.1 26.9 13.5 13.2 50.7 40.9 5.8 18.0 14.3 10.8 20.5 15.4 24.5 20.1 36.2 15.4 58.6 246.3 136.9 20.9 41.6 82.0 28.8 35.7 30.9 11.8 9.3 34.0 113.1 46.9 21.3 14.9 24.6 32.0 19.0 10.9 16.4 21.5 37.3 76.9 19.8 49.3 115.8 32.0 34.6 20.5 87.4 45.4 8.3 49.9 22.1 44.9 34.1 3.7 21.2 17.1 16.2 16.6 15.8 16.2 25.0 33.8 27.7 15.5 15.3 57.3 44.6 25.5 26.5 29.4 18.8 73.5 67.9 26.3 68.9 24.4 11.8 21.9 11.4 112.3 16.5 40.6 0.0 3.5 0.2 1.2 2.1 1.0 0.4 1.4 1.5 3.5 0.4 1.0 1.4 0.3 0.9 1.5 1.3 0.9 2.0 23.6 21.3 31.0 30.3 23.2 33.4 47.4 35.2 44.7 26.9 40.9 24.5 6.5 9.6 6.4 11.8 5.3 5.4 4.6 2.1 5.7 9.8 5.4 4.3 10.0 5.7 1.4 1.8 6.2 4.6 6.4 3.6 0.0 20.5 139.8 2.6 13.5 7.0 5.3 13.9 12.4 13.8 11.1 29.5 6.6 5.8 10.2 13.3 8.2 16.1 32.5 20.2 14.2 2.9 0.0 25.8 8.4 398.5 40.4 27.0 21.4 3.7 39.4 3.1 4.1 9.0 11.8 11.5 3.4 48.2 5.9 6.4 6.4 5.0 2.2 5.2 6.6 10.7 11.3 11.1 8.1 6.2 1.8 4.4 5.3 33.6 4.0 3.7 PLCE1 "KIAA1516, NPHS3, PLCE" ENSG00000138193 "Phospholipase C epsilon 1" Q9P212 10 93993931-94332823 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;Astrocytes: 69.5;Distal enterocytes: 79.6;Inhibitory neurons: 83.9;Muller glia cells: 82.7;Oligodendrocyte precursor cells: 123.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015597, HPA015598" Enhanced Supported Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA015597: AB_1855321, HPA015598: AB_1855322" "unprognostic (4.73e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.59e-3)" "unprognostic (3.01e-1)" "unprognostic (2.96e-1)" "unprognostic (1.73e-2)" "unprognostic (4.76e-3)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-3)" "unprognostic (3.56e-1)" "unprognostic (3.92e-2)" "unprognostic (3.54e-2)" "unprognostic (4.30e-2)" 3.8 2.6 4.5 2.8 4.1 0.2 2.7 3.1 5.6 8.0 7.0 12.6 4.0 9.0 5.3 1.7 4.4 2.5 12.4 3.9 4.7 8.4 0.7 7.3 0.7 3.9 4.8 3.9 14.7 0.8 4.4 2.9 4.0 3.8 7.5 7.3 2.3 5.4 4.1 1.1 5.2 4.2 3.2 6.2 8.3 2.0 5.4 0.5 9.8 6.3 0.6 5.6 5.6 4.2 4.0 6.7 1.8 1.1 0.7 3.2 1.9 2.8 0.6 0.3 0.4 5.3 1.3 0.8 1.3 2.3 1.3 2.6 2.2 0.4 0.6 0.4 2.3 0.5 4.0 0.5 0.0 0.9 0.3 1.8 0.0 1.1 0.0 6.8 0.0 0.4 0.5 0.3 4.2 0.3 0.8 0.9 0.7 7.9 5.0 0.1 3.9 0.2 0.2 10.3 0.9 1.5 3.3 3.6 0.7 4.1 3.5 0.6 0.6 3.0 5.9 2.0 4.4 0.6 0.3 0.4 3.5 1.1 2.2 0.1 0.1 0.0 0.3 0.2 0.2 0.5 0.3 0.2 0.1 0.7 0.5 0.4 0.1 0.2 0.2 0.2 0.1 0.1 4.5 4.1 3.1 5.6 3.9 4.7 3.9 4.8 4.0 3.2 5.4 4.2 8.2 70.5 5.4 69.5 7.0 8.2 9.7 6.8 2.2 12.2 3.6 3.6 34.7 4.3 12.3 0.0 0.0 3.7 2.9 79.6 1.9 1.1 20.7 26.7 18.4 9.7 1.8 0.0 3.1 6.4 2.5 15.3 29.6 10.6 0.0 7.2 4.2 1.6 0.7 6.7 83.9 9.7 4.1 2.4 5.2 5.3 12.2 1.3 7.2 5.6 1.2 82.7 4.1 123.1 2.4 4.2 54.8 23.3 0.9 7.5 11.0 2.5 10.6 18.7 6.6 30.8 37.7 3.7 8.0 1.7 7.4 1.9 4.3 3.7 41.1 10.5 PLCH2 "KIAA0450, PLC-eta2, PLCeta2, PLCL4, RP3-395M20.1" ENSG00000149527 "Phospholipase C eta 2" O75038 1 2425980-2505532 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 44.8;skin 1: 59.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 102.5;Cone photoreceptor cells: 75.0;Oligodendrocytes: 37.4;Rod photoreceptor cells: 169.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HBEC3-KT: 130.9;hTCEpi: 58.9;hTERT-HME1: 32.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072705 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA072705: AB_2732211" "unprognostic (2.06e-3)" "unprognostic (1.30e-2)" "unprognostic (1.09e-3)" "unprognostic (3.84e-3)" "unprognostic (1.99e-1)" "unprognostic (1.59e-2)" "unprognostic (7.39e-2)" "unprognostic (7.70e-2)" "unprognostic (7.58e-2)" "unprognostic (9.28e-2)" "unprognostic (2.26e-1)" "unprognostic (5.95e-2)" "unprognostic (6.61e-3)" "unprognostic (8.43e-2)" "unprognostic (1.07e-1)" "unprognostic (8.64e-2)" "unprognostic (5.80e-2)" 0.6 1.4 1.0 3.9 1.7 2.2 6.2 7.9 4.8 6.3 0.0 1.1 2.2 0.3 1.7 19.3 3.2 2.9 0.2 2.4 1.0 0.8 2.1 1.8 5.3 3.3 3.1 0.1 5.1 0.0 7.9 0.4 3.6 14.6 0.8 44.8 16.4 5.8 0.2 59.6 3.3 0.1 1.2 5.5 2.0 0.6 6.9 4.4 1.7 0.0 6.5 9.1 18.3 7.2 0.3 0.5 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.2 0.2 0.0 17.1 0.0 130.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 58.9 0.0 32.8 0.0 0.0 0.0 0.0 3.1 0.3 0.6 0.0 0.0 0.1 1.9 1.4 0.1 0.1 0.0 0.2 6.1 14.7 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.4 0.3 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.0 0.6 0.2 1.0 1.7 7.9 4.8 2.4 1.0 3.3 3.1 3.6 1.2 6.9 7.2 0.2 0.0 1.7 2.9 6.1 15.4 14.5 22.8 10.8 102.5 1.7 5.5 3.3 2.8 10.8 0.0 75.0 0.0 7.3 0.7 1.9 0.1 0.1 0.7 0.2 0.7 1.2 0.0 9.3 0.0 0.0 0.4 1.5 1.4 0.0 0.1 0.0 4.9 0.1 26.9 19.8 1.9 2.0 0.3 1.1 0.2 0.0 0.5 3.6 1.9 0.4 14.9 7.2 2.5 37.4 0.5 0.6 0.0 1.9 4.9 3.8 33.5 5.8 169.0 0.0 0.0 1.0 0.2 0.3 13.0 14.6 0.0 7.0 0.1 0.5 9.2 PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600404-171810950 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 519.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 57.5;SK-MEL-30: 31.1;TIME: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004527, HPA042396, HPA066938" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "CAB004527: AB_677324, HPA042396: AB_2677977, HPA066938: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.76e-6)" 7.8 26.4 9.2 6.6 24.7 7.8 7.5 18.4 13.6 10.4 4.5 14.6 46.9 6.2 2.8 33.0 6.4 86.8 24.4 10.5 14.3 12.0 33.7 4.7 9.1 24.8 22.0 24.2 21.2 1.6 2.3 10.7 23.5 3.4 14.7 0.5 13.8 6.0 2.5 29.2 43.9 4.8 14.7 15.7 8.2 5.0 19.0 4.1 3.7 6.8 10.8 5.1 12.4 41.4 4.5 7.2 3.7 1.4 11.2 12.6 7.7 2.3 9.9 3.5 4.3 1.1 6.4 0.0 17.0 0.9 24.0 15.2 0.6 2.0 5.7 3.6 3.2 4.2 11.5 26.1 4.9 7.3 18.9 4.9 10.9 4.2 2.0 10.0 57.5 1.2 2.8 0.0 0.9 1.3 0.0 6.4 0.8 11.9 5.1 0.2 1.5 0.1 8.9 1.8 0.1 0.1 7.9 4.7 31.1 5.1 9.0 9.7 50.7 1.5 5.7 4.0 2.5 9.6 8.2 0.1 6.7 8.6 1.9 8.3 1.8 2.3 0.3 1.1 2.6 0.0 0.2 0.6 0.6 0.0 0.0 0.1 1.0 2.2 0.4 0.0 0.8 0.6 9.2 24.7 18.4 13.6 10.5 14.3 24.8 22.0 23.5 14.7 19.0 41.4 7.7 0.0 4.7 2.0 0.9 7.1 3.4 11.0 10.8 0.4 4.9 5.6 33.6 57.2 11.1 1.8 0.0 3.0 1.9 37.5 3.9 8.4 13.1 1.0 4.8 7.4 4.2 6.3 8.9 3.4 3.7 15.7 27.0 1.3 27.9 10.4 6.4 15.9 20.0 0.0 12.1 23.6 6.1 13.2 2.4 9.5 10.5 10.2 12.4 98.4 5.4 0.0 1.0 12.5 519.6 2.4 18.3 4.5 3.4 0.7 38.3 48.0 9.9 0.1 19.7 3.8 8.4 6.1 5.3 93.5 34.9 2.3 2.3 12.1 17.8 4.7 PLD4 C14orf175 ENSG00000166428 "Phospholipase D family member 4" Q96BZ4 14 104924713-104937761 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.4;brain: 16.7;lymphoid tissue: 11.3" "Cell type enriched" "Detected in many" 7 "dendritic cells: 284.8" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 3621.6" "Lineage enriched" "Detected in all" 5 "dendritic cells: 3621.6" "Group enriched" "Detected in some" 4 "HMC-1: 127.3;RPMI-8226: 85.5;THP-1: 191.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051512 Uncertain NA NA 2900000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA051512: AB_2681515" "unprognostic (4.50e-3)" "unprognostic (1.78e-4)" "unprognostic (7.12e-2)" "unprognostic (5.30e-3)" "unprognostic (5.54e-2)" "unprognostic (2.91e-3)" "unprognostic (2.56e-1)" "unprognostic (4.76e-3)" "unprognostic (1.45e-3)" "unprognostic (1.19e-3)" "unprognostic (3.45e-3)" "unprognostic (3.89e-1)" "unprognostic (6.90e-3)" "unprognostic (8.94e-2)" "unprognostic (2.83e-1)" "unprognostic (1.28e-2)" "unprognostic (2.41e-1)" 0.4 1.0 5.1 5.7 4.7 13.4 1.5 7.0 7.1 1.0 0.4 0.8 3.8 1.0 0.2 0.6 1.8 2.4 0.5 4.5 7.3 0.8 0.5 1.8 11.3 15.7 6.8 0.5 1.1 1.2 2.1 0.8 10.3 1.7 0.5 0.5 3.5 1.8 0.3 0.6 5.1 0.5 13.9 10.4 2.8 0.6 9.4 2.8 0.6 0.0 9.4 1.9 0.4 16.7 0.1 0.2 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 9.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 127.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.1 10.7 0.1 0.0 0.1 30.0 0.1 85.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 191.5 0.0 0.1 0.3 0.1 0.2 0.4 0.0 0.1 0.2 1.6 0.3 4.6 43.0 699.5 1.0 188.4 1.9 222.7 0.8 1.2 545.8 198.4 1.7 0.4 9.8 25.4 297.9 3621.6 1.0 72.9 5.1 4.7 7.0 7.1 4.5 7.3 15.7 6.8 10.3 13.9 9.4 16.7 0.8 0.0 0.0 0.3 34.7 0.4 0.1 0.0 0.0 2.7 0.6 2.8 1.4 0.0 0.0 0.0 0.0 0.2 284.8 0.0 0.0 0.0 0.7 0.1 0.3 2.7 0.0 5.5 0.1 0.0 0.4 1.1 1.1 0.4 3.8 0.0 0.0 0.0 30.6 1.7 0.1 0.0 0.0 1.3 32.0 4.7 0.0 38.0 5.4 22.5 11.3 0.1 2.1 0.5 0.1 0.0 0.0 0.0 2.3 0.1 0.0 0.1 0.0 1.1 6.6 1.6 0.3 1.6 1.6 0.0 0.4 0.3 2.2 0.0 0.1 0.0 PLEC "EBS1, PCN, PLEC1, PLTN" ENSG00000178209 Plectin Q15149 8 143915153-143976734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant, Epidermolysis bullosa, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 256.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "PC-3: 384.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003847, HPA025967, HPA029906" Enhanced Supported "Intermediate filaments,Focal adhesion sites,Cytosol" NA NA 7400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Intermediate filaments, Cytosol" "Focal adhesion sites" "CAB003847: AB_562198, HPA025967: AB_10601671, HPA029906: AB_10602279" "unprognostic (1.02e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.72e-3)" "unprognostic (1.13e-2)" "unprognostic (2.85e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (7.98e-6)" "unprognostic (2.30e-1)" "unprognostic (4.04e-2)" "unprognostic (6.58e-2)" "unprognostic (5.58e-3)" 41.8 30.9 44.2 22.6 25.4 43.2 37.9 20.4 39.7 57.4 6.7 58.0 21.1 55.2 8.5 59.7 47.9 22.8 78.9 42.2 31.0 30.0 31.3 49.2 22.1 48.5 28.6 47.1 27.6 8.1 33.0 18.3 30.8 49.5 13.0 3.9 42.9 19.8 256.5 83.1 53.8 27.7 28.8 46.1 49.1 15.3 43.2 14.4 25.7 74.7 15.8 56.5 55.7 25.9 92.6 247.3 15.1 20.3 31.6 66.9 62.8 125.9 49.3 32.3 18.7 39.2 88.5 8.9 82.9 179.7 54.6 98.9 10.3 162.6 13.3 58.7 10.0 24.9 268.0 34.0 54.0 9.6 26.1 71.8 40.7 84.6 164.2 28.3 43.0 7.6 16.2 25.9 39.7 175.3 5.1 19.8 12.2 29.4 384.8 1.8 46.2 24.6 67.7 147.7 16.6 16.8 217.4 50.0 21.1 21.7 55.7 12.4 125.7 117.8 217.3 110.6 155.1 4.7 3.7 6.3 106.9 15.2 176.2 0.0 2.0 0.1 0.6 1.7 1.3 0.6 1.2 0.9 1.6 0.6 0.8 0.5 0.4 0.3 1.2 1.3 1.4 2.0 44.2 25.4 20.4 39.7 42.2 31.0 48.5 28.6 30.8 28.8 43.2 25.9 83.8 28.9 15.6 78.0 27.0 108.0 53.1 62.9 50.7 15.8 29.4 27.9 39.3 31.5 42.9 40.5 25.0 34.4 27.1 257.8 0.0 39.3 1.4 39.4 52.6 68.2 32.2 11.8 47.3 20.2 32.1 45.7 170.2 57.3 8.2 14.4 63.1 69.0 35.2 30.3 36.5 79.9 10.2 67.5 100.4 5.0 44.4 61.2 33.8 27.2 54.9 11.2 15.5 14.6 3.4 157.8 194.1 74.9 39.3 144.9 124.9 4.6 50.3 10.8 6.6 42.1 61.5 1.2 7.1 72.2 76.7 69.0 35.0 18.8 61.6 121.0 PLEKHA4 PEPP1 ENSG00000105559 "Pleckstrin homology domain containing A4" Q9H4M7 19 48837097-48868617 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 53.4;Smooth muscle cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 63.4;BJ hTERT+ SV40 Large T+ RasG12V: 49.5;SK-MEL-30: 77.0" "Low region specificity" "Detected in some" "Region enriched" "Detected in many" 6 "spinal cord: 45.0" "HPA042978, HPA048473" Uncertain Approved "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "Cytokinetic bridge, Centriolar satellite" "HPA042978: AB_2678249, HPA048473: AB_2680409" "prognostic favorable (1.97e-4)" "unprognostic (4.39e-1)" "unprognostic (8.16e-2)" "unprognostic (2.85e-2)" "unprognostic (3.98e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (8.68e-4)" "unprognostic (5.09e-2)" "unprognostic (1.01e-2)" "unprognostic (1.17e-1)" "unprognostic (1.18e-2)" "unprognostic (2.95e-1)" "unprognostic (3.84e-2)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-3)" "unprognostic (6.38e-2)" 34.0 24.6 8.8 12.1 8.8 0.7 31.7 8.0 9.5 28.7 10.9 43.0 5.6 34.6 5.0 14.3 30.5 11.1 41.4 8.7 10.6 32.4 32.8 25.7 5.8 16.9 14.7 47.5 13.2 9.5 29.9 5.6 10.4 28.3 3.9 2.5 15.1 8.4 19.3 17.2 16.0 10.7 10.8 16.2 21.1 11.0 12.4 5.5 31.0 13.1 3.3 34.4 21.7 10.3 9.0 0.5 9.9 63.4 14.2 41.7 8.0 7.0 24.7 26.8 49.5 5.9 2.5 0.4 11.8 9.8 10.4 2.7 3.5 3.6 4.2 0.0 3.4 2.3 1.7 6.6 11.0 0.0 14.2 21.5 2.2 15.6 1.0 11.1 8.0 11.2 9.5 5.3 7.4 5.4 3.2 0.5 1.5 6.0 0.8 0.3 31.5 0.6 8.3 0.1 0.0 11.0 3.0 2.6 77.0 2.5 3.9 3.0 1.3 8.5 6.8 11.2 1.8 28.3 25.4 5.3 10.2 0.7 23.0 0.0 0.3 0.9 1.8 0.3 1.3 1.7 1.7 1.1 0.1 3.9 2.8 2.6 0.1 0.8 0.3 1.2 0.6 0.9 8.8 8.8 8.0 9.5 8.7 10.6 16.9 14.7 10.4 10.8 12.4 10.3 6.4 0.0 18.7 2.3 1.4 9.6 31.3 17.6 12.0 0.7 11.4 18.3 37.1 17.2 27.2 7.3 0.0 3.3 2.9 3.2 1.9 23.3 0.8 11.6 34.1 7.0 1.2 3.2 0.4 5.1 6.8 41.7 7.7 11.6 0.0 18.8 6.4 13.3 2.9 0.0 0.5 2.5 4.1 0.8 9.2 2.0 41.3 1.9 12.4 1.9 1.3 9.9 2.1 0.5 0.2 6.9 0.5 53.4 0.7 29.8 0.7 14.6 20.5 1.0 6.6 33.0 48.4 4.0 3.7 5.7 9.8 2.9 2.4 16.0 3.3 21.4 PLG ENSG00000122194 Plasminogen P00747 6 160702238-160754097 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 2666.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 1772.7" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000668, CAB016678, HPA021602, HPA048823" Supported "Secreted to blood" NA NA 140000000000 45000000000 "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: AB_2680532" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favorable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" 0.4 0.4 0.3 0.2 0.4 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.3 0.2 0.0 0.1 2.4 0.5 0.1 0.2 0.3 240.9 2666.4 0.4 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.1 0.9 0.0 0.1 0.2 0.1 0.0 0.0 0.5 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.6 30.0 0.0 1.8 0.0 0.0 0.3 0.0 19.6 0.0 0.2 3.0 0.1 1.2 0.0 24.0 0.6 0.0 0.0 0.0 0.0 0.1 1.3 0.0 28.5 1772.7 0.1 0.0 0.5 0.0 0.0 35.4 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 235.7 1.5 0.1 0.0 0.4 0.2 0.4 0.4 0.0 0.0 0.0 2.3 0.1 0.0 0.0 PLGLB1 "PLGL, PRP-B" ENSG00000183281 "Plasminogen like B1" Q02325 2 87002559-87021852 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enriched" "Detected in all" 6 "liver: 234.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 95.9" "Cancer enriched" "Detected in single" 7 "liver cancer: 0.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (7.25e-2)" "unprognostic (7.25e-2)" "unprognostic (2.35e-1)" "unprognostic (1.15e-1)" "unprognostic (1.75e-2)" "unprognostic (1.39e-5)" "unprognostic (7.04e-3)" "unprognostic (1.15e-1)" "unprognostic (8.53e-4)" "unprognostic (1.60e-1)" "unprognostic (4.56e-4)" "unprognostic (9.90e-3)" "unprognostic (2.96e-5)" "unprognostic (1.02e-1)" "unprognostic (1.16e-1)" "unprognostic (4.32e-2)" "unprognostic (3.98e-5)" 3.6 5.5 19.9 4.5 19.9 8.5 3.6 33.4 26.5 6.9 21.3 4.9 3.9 5.9 8.2 4.0 4.3 4.7 5.9 20.0 20.3 8.5 234.9 3.3 7.9 16.7 17.4 6.7 4.1 2.2 9.5 2.3 16.0 6.6 2.7 42.5 4.8 3.2 8.8 14.2 5.3 2.4 15.0 9.5 4.0 4.3 20.0 7.2 5.6 4.4 4.3 4.9 4.9 19.6 2.7 3.7 4.6 2.6 3.6 5.2 4.5 3.2 2.3 1.7 2.6 2.9 6.9 7.3 3.3 1.3 1.3 2.4 1.2 0.5 1.8 8.2 3.1 5.8 6.6 3.1 2.5 3.5 1.5 4.0 4.2 4.7 4.8 7.9 0.8 8.0 3.0 5.9 2.2 3.9 13.3 11.5 5.9 2.4 2.4 3.1 1.7 3.9 4.5 2.9 3.6 4.0 2.9 2.5 2.7 4.6 1.3 7.6 5.0 3.3 2.3 2.3 2.0 6.7 5.1 2.9 1.9 4.7 1.9 1.9 0.3 0.4 0.7 0.1 0.6 1.2 0.7 0.5 0.1 0.8 0.9 0.5 1.0 0.4 0.3 0.6 1.1 0.1 19.9 19.9 33.4 26.5 20.0 20.3 16.7 17.4 16.0 15.0 20.0 19.6 1.3 0.0 3.4 0.7 1.0 1.1 0.3 0.4 1.2 10.3 1.1 1.0 2.6 1.5 1.5 0.0 6.2 0.2 1.5 0.7 0.0 1.1 0.8 1.0 1.0 1.6 1.2 4.0 0.9 0.2 0.2 1.6 0.5 0.9 0.0 1.0 1.8 95.9 0.2 5.0 1.1 2.5 0.0 1.3 0.4 0.3 1.2 1.1 3.6 0.0 1.6 2.7 1.0 0.0 0.8 0.3 0.3 1.9 0.9 0.5 0.7 1.8 2.3 18.2 0.0 2.5 1.0 0.7 0.5 1.5 1.3 0.0 1.4 0.9 0.9 0.3 PLGLB2 PLGP1 ENSG00000125551 "Plasminogen like B2" Q02325 2 87748087-87759476 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enriched" "Detected in some" 163 "liver: 454.4" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 76.3" "Cancer enriched" "Detected in single" 25 "liver cancer: 1.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 12: NES - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.10e-2)" "unprognostic (8.78e-2)" "unprognostic (3.42e-2)" "unprognostic (7.03e-4)" "unprognostic (1.68e-2)" "unprognostic (3.77e-1)" "unprognostic (1.82e-2)" "unprognostic (5.74e-2)" "unprognostic (2.94e-1)" "unprognostic (5.04e-4)" "unprognostic (6.39e-2)" "unprognostic (4.06e-2)" "unprognostic (3.22e-2)" "unprognostic (7.11e-2)" 0.4 0.8 1.0 0.5 0.7 0.5 0.3 2.0 1.0 0.8 0.2 0.3 0.2 0.6 0.6 0.6 0.7 0.2 0.8 0.9 0.1 0.9 454.4 0.3 0.9 0.2 0.3 0.5 1.3 0.4 0.9 0.4 0.2 0.7 0.3 2.7 0.4 0.4 0.6 1.0 0.5 0.2 0.1 0.9 0.5 1.0 0.2 0.8 0.5 0.5 0.7 0.3 0.2 0.6 0.0 0.1 1.2 0.3 0.4 0.5 0.4 0.6 0.4 0.1 0.2 0.1 0.3 0.7 0.4 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.5 1.2 0.0 0.1 0.5 0.2 0.5 0.3 0.1 0.2 1.0 0.4 0.7 0.0 0.1 0.4 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.0 0.4 0.0 0.0 0.7 0.2 0.2 0.0 0.3 0.0 0.3 0.2 0.1 0.5 0.4 0.3 0.5 1.2 0.3 0.4 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.1 0.1 0.0 0.1 0.0 1.0 0.7 2.0 1.0 0.9 0.1 0.2 0.3 0.2 0.1 0.2 0.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 4.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 76.3 0.1 0.0 0.3 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 PLIN3 "M6PRBP1, PP17, TIP47" ENSG00000105355 "Perilipin 3" O60664 19 4838341-4867694 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 268.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006427, HPA066538" Uncertain Supported "Lipid droplets" NA Yes 11000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" "HPA006427: AB_1079289, HPA066538: AB_2685687" "unprognostic (1.18e-1)" "unprognostic (4.86e-2)" "unprognostic (1.55e-2)" "prognostic favorable (2.62e-4)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.27e-5)" "prognostic unfavorable (7.67e-6)" "unprognostic (2.27e-1)" "unprognostic (1.28e-1)" "unprognostic (4.34e-2)" "unprognostic (8.24e-2)" "prognostic unfavorable (9.15e-7)" "unprognostic (2.62e-1)" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (2.39e-2)" 30.8 69.9 23.3 41.4 39.6 70.8 29.5 44.2 27.5 50.4 25.9 37.6 70.8 22.6 14.4 124.7 22.9 34.5 25.3 22.1 28.6 38.0 26.5 25.7 29.1 51.1 36.1 40.0 20.3 9.8 9.3 33.3 48.9 28.0 20.9 1.7 45.9 21.0 112.0 87.5 73.9 23.9 36.2 32.3 28.5 34.3 39.1 28.0 24.8 36.4 33.0 37.5 55.4 66.0 138.2 79.1 53.6 50.5 59.8 189.8 24.1 196.8 178.9 152.0 142.9 52.6 124.9 72.5 43.3 242.2 82.1 61.3 25.1 108.2 88.2 82.7 35.4 79.1 43.0 97.8 41.4 56.7 112.9 147.1 46.2 107.4 23.6 90.5 81.2 23.5 122.4 31.3 192.1 57.1 78.3 72.9 42.5 63.3 127.7 136.2 74.9 40.2 133.8 31.7 2.3 26.3 62.5 55.5 49.5 43.2 70.4 125.9 125.1 83.3 80.5 333.8 102.9 44.1 58.9 50.8 250.7 79.6 97.3 128.3 141.7 64.8 13.8 100.4 14.6 46.3 24.7 15.9 109.1 36.3 19.4 12.4 173.9 39.5 76.7 82.8 34.1 86.4 23.3 39.6 44.2 27.5 22.1 28.6 51.1 36.1 48.9 36.2 39.1 66.0 19.2 19.2 25.6 5.5 28.5 142.2 62.9 58.8 90.0 0.4 108.0 43.1 2.3 14.3 51.3 11.0 2.1 152.2 34.4 169.7 37.2 114.7 9.7 65.2 50.9 27.7 40.7 18.5 0.8 86.8 77.3 62.9 33.1 78.4 55.8 112.9 26.0 18.2 101.2 0.0 1.1 67.0 28.5 57.8 103.4 14.0 35.8 74.7 55.2 2.8 62.3 23.9 15.5 5.0 17.1 243.4 223.0 53.0 37.1 39.3 268.8 38.8 65.2 0.7 52.6 37.8 66.2 75.1 14.6 109.0 229.3 194.8 20.3 193.4 54.8 69.2 PLOD1 "LH1, LLH, PLOD" ENSG00000083444 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" Q02809 1 11934205-11975538 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 236.8;Sertoli cells: 105.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049137, HPA055799" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles Nucleoplasm "HPA049137: AB_2680649, HPA055799: AB_2682924" "unprognostic (1.00e-1)" "unprognostic (2.69e-3)" "unprognostic (9.21e-3)" "unprognostic (5.43e-2)" "unprognostic (7.53e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (4.15e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.91e-12)" "unprognostic (2.79e-1)" "unprognostic (7.12e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.43e-4)" 58.1 34.6 46.3 35.2 51.2 16.1 41.2 48.6 56.6 65.4 46.4 47.3 37.7 65.0 30.5 21.3 51.1 42.0 71.2 44.5 47.4 45.5 78.1 44.4 15.4 49.6 50.8 54.4 39.0 36.9 29.6 83.8 52.4 34.7 23.2 10.6 75.9 40.6 40.5 27.2 35.6 78.4 44.8 31.5 35.5 11.6 52.2 7.9 34.9 41.6 12.9 42.4 36.0 53.1 112.5 91.4 51.3 239.7 343.4 190.6 39.0 330.4 436.1 170.4 287.1 105.2 71.5 63.1 339.5 367.3 125.9 93.4 75.6 115.6 115.6 66.2 78.3 34.0 136.6 137.3 212.5 21.9 162.7 234.0 59.7 206.2 81.9 573.3 305.0 14.8 97.6 30.9 180.2 71.1 5.7 58.6 22.9 115.4 131.6 25.8 100.0 141.0 98.7 24.3 19.2 77.7 137.3 97.4 164.8 80.4 48.3 55.9 298.7 190.1 141.6 236.3 161.9 71.4 123.7 38.7 425.1 75.5 316.8 0.0 40.3 2.0 17.3 34.4 3.1 1.7 3.0 8.4 32.7 3.4 1.2 6.4 35.5 5.4 32.3 4.9 2.0 22.6 46.3 51.2 48.6 56.6 44.5 47.4 49.6 50.8 52.4 44.8 52.2 53.1 19.4 0.0 7.9 9.4 3.7 7.0 8.0 22.8 8.0 5.7 17.9 17.5 18.3 8.6 8.6 11.0 2.1 39.7 8.7 14.8 3.9 30.3 1.0 11.0 62.2 33.9 8.4 3.0 4.2 9.8 236.8 47.5 17.3 24.8 0.0 20.4 36.8 37.1 46.3 6.7 5.8 12.5 4.1 26.5 8.3 2.4 44.4 16.3 10.6 15.9 17.9 7.9 15.5 3.0 9.8 22.4 15.4 24.5 19.4 8.0 41.5 16.7 4.5 3.1 105.2 77.2 47.3 0.5 3.3 7.4 5.1 33.7 5.5 37.1 16.6 3.9 PLOD2 LH2 ENSG00000152952 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" O00469 3 146069440-146163653 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 130.9;Basal respiratory cells: 115.1;Distal enterocytes: 143.7;Extravillous trophoblasts: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBF TERT88: 636.0;hTERT-RPE1: 723.8;U-87 MG: 566.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025898, HPA069126" Approved Uncertain Nucleoli,Cytosol "Intracellular and membrane" NA NA 21000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "CAB025898: , HPA069126: " "unprognostic (8.68e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (2.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (1.29e-3)" "prognostic unfavorable (7.64e-10)" "prognostic unfavorable (1.42e-4)" "unprognostic (2.97e-2)" "unprognostic (3.36e-2)" "unprognostic (6.27e-3)" "unprognostic (2.24e-1)" "prognostic unfavorable (4.99e-11)" "prognostic unfavorable (2.83e-4)" "unprognostic (6.07e-2)" "unprognostic (4.06e-2)" "unprognostic (4.41e-3)" 63.1 20.1 13.4 35.6 14.5 1.1 18.6 15.1 17.2 10.2 19.4 36.2 42.2 23.5 13.4 18.2 11.4 41.5 22.1 13.3 15.1 26.1 57.3 12.9 3.8 23.1 18.1 20.5 18.7 16.5 7.9 80.6 16.3 13.2 29.9 56.6 9.5 16.2 3.0 3.9 35.0 46.8 17.8 5.4 20.1 8.5 20.6 10.5 90.0 3.9 5.5 25.7 10.0 17.6 134.5 94.3 29.0 9.5 102.5 109.6 73.2 465.5 141.6 247.7 463.0 7.2 13.4 0.0 88.8 79.5 113.1 27.8 34.0 400.5 636.0 0.6 53.5 33.3 84.3 66.9 262.5 0.1 0.6 192.9 56.5 215.2 104.1 723.8 347.7 0.1 45.1 1.8 441.6 48.8 0.3 0.6 18.5 0.3 40.0 0.2 19.2 0.6 105.0 6.5 14.5 0.5 370.3 39.4 39.9 135.1 107.5 4.2 440.4 304.2 92.2 97.8 280.7 138.9 20.9 0.5 566.5 0.4 55.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 13.4 14.5 15.1 17.2 13.3 15.1 23.1 18.1 16.3 17.8 20.6 17.6 29.1 16.0 11.4 130.9 0.4 7.0 6.4 115.1 30.1 17.1 23.7 10.2 14.3 44.3 47.0 27.6 35.5 9.2 0.3 143.7 9.8 64.5 0.5 35.4 13.8 24.3 19.8 4.6 22.8 53.1 130.6 68.1 19.9 38.7 0.0 42.7 21.0 65.2 5.1 0.0 46.4 19.5 22.4 1.0 2.5 1.2 13.1 3.0 14.2 21.5 0.7 53.8 0.0 64.3 6.0 82.4 48.8 4.9 1.3 8.9 50.5 8.2 33.0 24.7 19.7 36.9 47.2 11.0 18.0 27.5 5.5 18.7 1.0 24.5 25.1 5.6 PLOD3 LH3 ENSG00000106397 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" O60568 7 101205977-101218420 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "melanoma: 115.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 20.3;monocytes: 22.5;T-cells: 12.6" "Cell line enhanced" "Detected in all" "Karpas-707: 695.6;WM-115: 680.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001236 Uncertain "Secreted to extracellular matrix" NA NA 1600000 "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA001236: AB_1855474" "unprognostic (1.15e-1)" "prognostic unfavorable (1.91e-5)" "prognostic unfavorable (3.26e-4)" "unprognostic (1.39e-1)" "unprognostic (2.76e-3)" "unprognostic (1.04e-2)" "unprognostic (6.26e-3)" "unprognostic (1.11e-3)" "unprognostic (8.00e-3)" "unprognostic (1.18e-2)" "unprognostic (4.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.21e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (8.52e-3)" "unprognostic (9.87e-2)" 41.9 27.3 43.6 22.9 53.2 19.6 32.8 54.9 58.5 33.3 46.8 37.8 25.7 38.9 11.7 12.2 32.5 18.8 42.6 43.6 46.3 36.3 54.1 37.5 14.6 61.1 52.3 26.3 41.8 21.5 27.1 35.0 58.9 24.2 15.3 3.9 19.4 18.6 15.3 19.1 35.9 26.0 49.4 35.3 30.0 12.9 51.7 8.0 25.3 11.8 7.5 35.2 25.2 71.9 71.7 62.4 27.1 168.2 116.2 83.9 51.4 125.5 135.9 122.7 88.6 98.0 89.0 5.6 140.2 211.4 100.7 83.0 50.0 72.0 31.2 37.8 23.8 7.2 70.7 97.3 157.6 31.5 57.4 90.8 67.6 71.6 55.4 120.2 110.9 4.6 68.4 695.6 84.2 194.5 3.4 72.1 53.5 120.5 94.9 21.8 35.1 108.3 42.0 19.1 21.2 116.0 81.1 116.2 288.1 66.8 21.9 105.2 100.5 188.1 94.9 228.1 155.0 38.5 75.9 5.2 112.4 74.2 680.2 0.0 18.1 4.4 12.6 21.8 10.9 3.7 9.3 8.3 16.5 2.2 4.1 4.5 1.8 3.6 22.5 20.3 6.7 9.5 43.6 53.2 54.9 58.5 43.6 46.3 61.1 52.3 58.9 49.4 51.7 71.9 34.1 22.4 8.7 11.1 9.7 8.9 10.8 18.9 8.0 5.7 8.1 9.1 16.1 21.5 8.7 25.8 14.6 20.4 22.0 37.6 1.9 40.2 0.6 10.8 29.9 28.5 16.2 19.1 11.9 31.6 71.6 34.2 17.9 20.5 19.7 25.9 26.7 18.3 50.1 8.4 10.8 18.0 4.1 23.3 18.3 2.1 26.1 23.2 62.2 4.7 18.9 7.7 12.3 10.1 33.4 36.1 37.8 14.7 19.7 8.0 45.8 8.8 9.3 7.3 19.7 14.3 29.8 8.9 12.4 1.9 4.8 18.9 12.5 18.4 27.3 5.2 PLTP BPIFE ENSG00000100979 "Phospholipid transfer protein" P55058 20 45898621-45912155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Hofbauer cells: 1640.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 33.1;eosinophil: 29.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 220.8;BEWO: 186.8;HHSteC: 233.2;HSkMC: 302.2;U-87 MG: 326.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032873 Approved "Secreted to blood" NA NA 9720000000 210000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032873: AB_2283977" "unprognostic (1.27e-1)" "unprognostic (3.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (4.19e-2)" "unprognostic (8.30e-2)" "unprognostic (3.19e-2)" "unprognostic (2.65e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (9.52e-8)" "unprognostic (3.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (9.68e-2)" 437.9 188.9 107.9 80.5 109.8 20.7 122.6 100.8 142.0 155.4 197.6 76.9 41.6 114.9 72.6 62.0 173.5 182.3 123.4 100.4 119.0 198.9 29.5 97.1 61.3 119.5 152.2 159.5 296.9 22.1 38.5 428.8 126.0 50.7 42.4 4.8 132.1 71.5 24.0 68.0 71.6 181.9 124.7 57.6 89.7 32.3 114.5 229.9 44.4 20.8 21.1 339.7 113.1 118.1 13.8 1.9 94.9 0.1 220.8 66.8 186.8 5.3 16.3 18.5 11.0 78.7 15.9 3.5 151.6 23.6 0.4 154.7 29.2 0.6 8.4 1.8 0.2 28.8 3.3 37.7 233.2 0.0 35.5 302.2 7.7 49.1 0.9 74.1 41.3 3.2 9.5 44.9 6.2 3.9 3.2 123.1 16.9 12.5 74.5 1.3 0.1 1.7 0.5 0.0 10.1 35.4 3.7 110.3 160.9 15.7 1.5 117.2 9.0 46.2 1.1 24.2 0.8 19.7 5.3 5.4 326.4 34.3 7.8 33.1 2.7 29.7 1.6 7.1 1.2 8.7 0.4 1.6 2.5 3.2 0.0 1.0 1.4 4.9 12.6 17.5 0.8 2.7 107.9 109.8 100.8 142.0 100.4 119.0 119.5 152.2 126.0 124.7 114.5 118.1 21.9 0.0 2.3 30.3 3.8 40.7 34.9 53.0 33.0 0.4 9.5 22.6 1.5 5.7 9.6 27.6 0.0 14.8 3.5 0.5 1.9 3.4 16.3 54.6 36.9 27.9 0.0 9.0 0.8 103.2 97.7 256.8 3.6 5.7 0.0 23.4 121.1 2.8 1640.3 3.3 1.4 1.2 12.2 254.0 40.9 24.9 307.9 71.8 35.6 4.7 3.8 13.8 7.2 0.5 0.2 9.9 0.0 199.0 11.8 15.7 0.0 18.2 70.8 1.1 32.9 16.1 35.6 5.7 7.3 24.0 35.8 31.7 3.3 99.5 0.7 18.4 PLXNA4 "DKFZp434G0625PRO34003, FAYV2820, KIAA1550, PLXNA4A, PLXNA4B" ENSG00000221866 "Plexin A4" Q9HCM2 7 132123332-132648688 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.8;brain: 29.1" "Group enriched" "Detected in many" 4 "Excitatory neurons: 235.3;Inhibitory neurons: 261.3" "Cancer enhanced" "Detected in many" "glioma: 3.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 29.1;hippocampal formation: 26.0" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.6" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.6" "Cell line enhanced" "Detected in some" "ASC diff: 25.2;HMC-1: 17.1;hTERT-RPE1: 22.1;RH-30: 18.5;TIME: 57.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029919, HPA052141, HPA075592" Approved Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA029919: AB_10671093, HPA052141: AB_2681745, HPA075592: AB_2732297" "unprognostic (2.05e-2)" "unprognostic (3.59e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.61e-6)" "unprognostic (5.76e-2)" "unprognostic (1.21e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-2)" "unprognostic (2.19e-1)" "unprognostic (7.99e-2)" "unprognostic (7.64e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-5)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (5.90e-2)" "unprognostic (1.42e-3)" 13.8 2.4 4.2 1.6 5.6 0.3 7.6 0.1 29.1 8.4 0.0 1.5 0.4 1.5 0.2 3.8 2.0 1.9 3.9 26.0 1.3 0.7 0.3 1.2 1.0 2.3 0.1 3.6 0.4 0.1 1.0 3.5 1.8 0.5 0.7 4.8 0.4 0.9 0.7 2.2 0.8 2.6 0.9 1.5 1.6 1.1 1.6 0.2 1.5 3.1 0.3 1.0 0.7 4.4 0.0 0.1 0.2 0.0 25.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 17.1 0.2 0.0 0.1 0.0 22.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.0 18.5 2.0 0.0 0.0 0.4 9.6 0.0 0.0 0.0 0.2 0.0 0.0 57.6 5.7 0.2 1.3 0.5 0.0 0.0 0.0 5.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.6 0.0 0.0 4.2 5.6 0.1 29.1 26.0 1.3 2.3 0.1 1.8 0.9 1.6 4.4 2.5 0.0 0.0 5.2 0.6 0.6 0.2 0.0 0.0 22.4 2.2 0.1 10.9 0.0 0.0 12.9 16.7 0.1 17.4 0.0 0.0 0.0 14.0 2.1 3.0 2.7 1.2 0.0 235.3 0.0 0.1 7.4 1.1 5.0 1.3 1.6 5.0 0.2 0.1 0.0 261.3 0.1 0.0 0.0 1.1 9.8 14.0 0.7 7.2 10.3 0.0 11.3 2.1 51.8 3.7 0.8 0.0 7.2 0.7 0.1 0.0 0.5 0.0 1.5 0.0 0.7 1.1 0.2 0.3 0.1 1.3 0.0 1.7 0.4 0.1 0.4 PLXNB2 "KIAA0315, MM1, PLEXB2" ENSG00000196576 "Plexin B2" O15031 22 50274979-50307646 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gastric mucus-secreting cells: 296.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "classical monocyte: 11.1;intermediate monocyte: 16.4;myeloid DC: 8.3;non-classical monocyte: 21.2;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 25 "dendritic cells: 8.3;monocytes: 21.2" "Cell line enhanced" "Detected in many" "SK-BR-3: 306.0" "Low region specificity" "Detected in all" HPA003100 Uncertain NA NA 78000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "HPA003100: AB_1079638" "unprognostic (4.43e-3)" "unprognostic (1.34e-1)" "unprognostic (2.16e-1)" "unprognostic (1.35e-3)" "unprognostic (6.28e-2)" "unprognostic (4.96e-2)" "unprognostic (2.69e-2)" "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (8.47e-3)" "unprognostic (9.84e-2)" "unprognostic (3.05e-2)" "prognostic favorable (4.75e-4)" "unprognostic (1.61e-2)" "unprognostic (9.41e-3)" "unprognostic (6.05e-2)" 28.1 42.9 12.5 31.2 11.5 14.6 25.0 43.2 14.7 38.8 61.2 45.8 45.0 44.0 7.7 48.6 50.6 51.5 20.1 9.8 12.3 42.5 33.2 40.2 22.8 21.1 22.9 49.6 47.5 22.5 33.8 35.7 16.9 40.0 16.4 9.3 53.0 45.6 7.0 50.2 50.3 20.2 13.2 74.2 87.4 18.6 16.7 7.8 53.8 3.1 15.3 33.3 41.3 15.5 77.0 125.0 58.2 78.7 35.2 43.2 98.9 104.8 55.8 36.8 36.1 87.0 102.0 59.9 114.1 86.8 22.6 145.9 10.2 77.5 9.1 10.8 50.3 11.2 233.2 64.3 79.2 2.0 54.6 67.8 117.5 39.1 29.9 64.8 30.0 0.1 15.9 14.3 38.7 132.4 1.1 21.0 15.5 45.9 31.3 64.2 97.8 18.8 39.4 237.5 29.6 53.6 103.0 306.0 22.6 16.9 119.9 72.0 64.9 76.1 112.6 39.7 37.9 8.1 1.5 11.0 60.4 3.5 101.5 0.0 11.1 0.0 0.0 16.4 0.2 0.0 0.0 0.0 8.3 0.0 0.0 0.1 0.4 0.1 21.2 6.6 0.5 7.7 12.5 11.5 43.2 14.7 9.8 12.3 21.1 22.9 16.9 13.2 16.7 15.5 15.2 64.1 54.5 33.0 6.2 22.9 22.7 70.6 23.9 15.5 48.2 40.8 15.5 62.9 94.4 136.1 16.7 3.1 11.8 172.0 3.9 93.1 9.0 87.8 33.4 24.8 49.7 2.1 13.5 57.5 29.3 28.7 296.2 72.6 5.1 43.2 21.4 58.8 36.3 13.5 9.3 77.9 40.7 46.8 38.2 4.3 24.2 49.9 14.2 24.4 45.1 54.1 2.1 4.5 1.6 117.5 111.4 19.2 4.9 54.3 110.5 36.4 154.6 10.4 26.3 18.9 35.8 2.2 2.4 34.5 25.1 6.4 4.1 48.5 56.5 45.1 PM20D1 "Cps1, FLJ32569" ENSG00000162877 "Peptidase M20 domain containing 1" Q6GTS8 1 205828025-205850132 "Enzymes, Predicted secreted proteins" "Hydrolase, Lyase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pancreas: 78.0;skin 1: 33.8" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 20.9;Gastric mucus-secreting cells: 7.1;Proximal tubular cells: 7.1" "Cancer enriched" "Detected in some" 32 "urothelial cancer: 30.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 2.2" "Lineage enriched" "Detected in single" 6 "T-cells: 2.2" "Cell line enriched" "Detected in single" 9 "Karpas-707: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to digestive system" NA NA 3300000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.30e-1)" "unprognostic (4.07e-2)" "unprognostic (4.83e-1)" "unprognostic (4.08e-3)" "unprognostic (1.17e-3)" "unprognostic (3.11e-1)" "unprognostic (1.20e-1)" "unprognostic (5.50e-2)" "unprognostic (5.81e-2)" "unprognostic (4.57e-2)" "unprognostic (7.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (1.68e-2)" 0.8 0.0 0.2 0.1 0.2 0.0 1.2 0.0 0.3 0.1 1.2 0.1 0.1 0.1 0.5 0.0 0.4 0.0 0.3 0.2 0.3 6.3 0.2 0.2 1.1 0.3 0.3 0.3 78.0 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.0 0.0 33.8 0.1 0.0 0.2 1.0 2.9 0.0 0.3 0.1 0.1 0.0 0.4 2.2 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.3 0.0 0.5 0.1 0.4 1.3 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 2.2 0.3 0.2 0.2 0.0 0.3 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.3 0.8 0.0 0.0 1.6 1.1 0.0 0.0 0.0 0.6 0.5 0.0 0.0 1.5 0.0 0.0 0.0 2.1 0.0 0.9 0.1 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.4 3.2 20.9 0.3 0.5 7.1 0.0 0.0 0.0 0.7 0.3 0.1 0.0 3.5 0.2 0.0 1.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.0 1.5 1.5 0.6 0.0 0.0 1.8 0.2 0.0 7.1 0.0 0.8 0.0 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.9 2.4 0.0 0.1 PMCH MCH ENSG00000183395 "Pro-melanin concentrating hormone" P20382 12 102196459-102197833 "Predicted secreted proteins" "Differentiation, Spermatogenesis" "Developmental protein, Hormone, Neuropeptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "brain: 92.8" "Group enriched" "Detected in some" 4 "B-cells: 2.7;Exocrine glandular cells: 2.0;monocytes: 1.0;T-cells: 1.7" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.8" "Region enhanced" "Detected in many" "hypothalamus: 92.8;thalamus: 60.2" "Immune cell enriched" "Detected in some" 10 "T-reg: 9.5" "Lineage enriched" "Detected in single" 85 "T-cells: 9.5" "Cell line enriched" "Detected in some" 8 "HDLM-2: 44.9" "Group enriched" "Detected in many" 129 "hypothalamus: 624.3;thalamus: 339.8" "Region enriched" "Detected in some" 34 "hypothalamus: 83.0" "HPA046055, HPA061884" Enhanced Supported "Secreted to blood" NA NA 274000 "Cluster 35: T-regs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA046055: AB_2679517, HPA061884: AB_2684632" "unprognostic (3.23e-3)" "unprognostic (8.04e-2)" "unprognostic (3.96e-4)" "unprognostic (2.09e-2)" "unprognostic (1.75e-1)" "unprognostic (7.73e-2)" "unprognostic (4.31e-3)" "unprognostic (1.43e-2)" "unprognostic (3.18e-3)" "unprognostic (4.51e-2)" "unprognostic (1.21e-1)" "unprognostic (2.16e-6)" "unprognostic (1.17e-2)" "unprognostic (1.93e-1)" "unprognostic (5.10e-2)" "unprognostic (3.53e-2)" 0.0 0.0 0.2 0.5 2.7 0.6 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 92.8 0.0 0.0 0.1 1.0 0.3 22.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.0 0.0 0.4 0.5 0.0 60.2 1.0 0.0 0.1 0.4 0.1 0.0 0.0 0.4 0.2 0.5 0.4 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.2 0.2 0.0 0.0 0.0 44.9 0.0 0.7 0.8 0.4 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.2 5.3 0.5 0.9 0.0 0.0 0.0 0.8 1.5 0.6 0.7 1.3 0.4 0.6 1.8 0.0 0.3 0.5 0.5 0.6 0.8 0.1 0.3 0.3 0.1 0.6 0.6 0.5 0.2 0.7 0.1 0.8 0.6 0.5 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.2 2.7 0.1 0.3 0.0 92.8 0.3 22.2 0.3 0.0 60.2 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 PMEL "D12S53E, gp100, Pmel17, SI, SIL, SILV" ENSG00000185664 "Premelanosome protein" P40967 12 55954105-55973317 "Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "cervix: 80.5;endometrium 1: 32.2;skin 1: 115.2" "Cell type enriched" "Detected in many" 32 "Melanocytes: 1472.7" "Cancer enriched" "Detected in many" 500 "melanoma: 2481.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 68 "SK-MEL-30: 8590.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031649 Enhanced Supported "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA 11000000 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "Golgi apparatus" "HPA031649: AB_2673976" "unprognostic (4.63e-1)" "unprognostic (8.93e-2)" "unprognostic (1.53e-1)" "unprognostic (1.60e-1)" "unprognostic (5.90e-2)" "unprognostic (6.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.46e-3)" "unprognostic (6.44e-2)" "unprognostic (1.21e-1)" "unprognostic (5.12e-2)" "unprognostic (3.98e-1)" "prognostic favorable (3.70e-4)" "unprognostic (2.86e-2)" "unprognostic (1.54e-1)" "unprognostic (7.60e-2)" "unprognostic (1.04e-1)" 3.3 0.8 0.2 0.8 0.2 1.8 8.3 0.7 0.5 80.5 0.3 1.3 1.6 32.2 1.5 0.7 1.2 1.6 0.6 0.3 0.0 2.1 5.0 0.9 5.6 0.0 0.4 4.3 2.3 1.7 0.7 2.8 0.1 0.9 1.2 0.4 3.5 0.8 0.3 115.2 2.1 3.5 0.0 0.5 1.1 4.8 0.0 0.7 1.1 0.2 2.2 1.3 4.0 0.3 14.8 1.1 5.6 0.2 83.6 0.6 126.2 0.9 0.8 1.9 2.0 12.8 6.0 2.6 6.1 0.8 0.3 2.5 0.6 1.0 1.6 3.0 2.1 2.4 2.5 0.7 0.3 1.0 1.4 0.5 1.0 1.2 0.6 1.3 1.0 1.1 0.5 1.8 0.5 2.7 0.4 1.0 17.1 2.8 0.3 1.6 3.5 1.5 1.4 2.7 0.5 2.6 0.3 2.5 8590.9 4.6 4.4 8.8 1.4 0.9 6.5 0.7 7.9 2.1 10.4 3.2 1.0 2.7 0.3 0.0 0.3 0.1 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.4 0.0 0.1 0.2 0.2 0.7 0.5 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.8 0.0 0.5 0.0 0.1 45.9 0.8 1.1 2.8 0.0 1.0 0.9 0.4 1.5 2.2 0.0 0.0 12.1 0.0 1.5 0.0 2.1 8.0 0.7 0.2 1.2 0.0 0.8 0.1 2.3 12.4 1.6 1.1 0.5 0.0 11.1 0.0 2.9 1.7 0.0 0.1 1.6 0.0 0.3 14.6 5.3 12.2 0.6 1472.7 1.0 0.6 0.2 0.0 0.0 0.1 1.0 0.6 0.7 1.2 0.5 2.4 2.8 1.0 0.0 0.0 0.2 1.7 3.9 2.6 1.0 10.2 24.9 0.4 1.3 1.6 0.4 PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 110.8" "Cell type enhanced" "Detected in many" "Ductal cells: 339.6;Muller glia cells: 325.9;Pancreatic endocrine cells: 827.5" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "SiHa: 206.1;U-2 OS: 129.9;U-251 MG: 481.8;WM-115: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" 50.5 14.5 24.2 14.2 75.5 1.3 25.1 38.8 29.9 94.8 1.8 30.7 6.5 48.4 7.1 7.6 19.9 26.0 29.2 24.0 28.3 16.2 3.8 21.8 7.4 32.9 34.1 14.9 31.3 5.0 13.5 3.9 38.8 110.8 8.4 23.6 30.5 20.6 33.2 18.1 12.6 28.8 27.0 6.6 12.2 5.3 36.1 2.4 13.6 13.6 8.9 13.1 29.6 26.2 32.2 75.4 2.3 3.9 2.4 0.0 0.8 4.9 0.2 1.7 0.8 1.5 97.4 0.2 17.7 7.4 51.8 121.1 1.6 100.8 1.3 1.0 4.1 0.0 23.2 0.1 1.5 0.3 0.8 1.2 55.8 4.4 12.1 16.5 13.0 67.8 0.8 1.2 6.2 66.1 3.8 0.7 9.4 15.0 9.6 0.3 36.0 11.3 24.2 0.0 17.7 13.7 206.1 120.3 15.1 5.6 18.8 4.1 33.1 17.9 129.9 1.9 481.8 5.9 0.8 0.5 8.1 1.1 237.1 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.8 0.2 0.1 6.3 1.8 1.2 0.1 0.0 0.1 23.9 0.5 0.6 24.2 75.5 38.8 29.9 24.0 28.3 32.9 34.1 38.8 27.0 36.1 26.2 59.4 57.7 32.3 4.9 32.7 167.0 143.1 120.6 30.7 59.0 38.0 23.0 23.2 125.8 31.7 11.0 2.1 0.2 27.8 57.3 3.9 339.6 1.2 33.4 88.8 55.6 10.1 0.0 19.1 62.5 4.1 40.5 5.1 80.2 59.8 17.5 24.7 0.5 6.1 1.7 32.7 16.9 14.2 3.5 68.0 2.7 3.1 13.4 32.0 31.9 5.8 325.9 0.0 17.6 9.0 827.5 54.2 21.8 25.3 203.1 6.2 2.7 10.1 11.5 72.3 43.8 155.2 0.2 8.8 10.0 178.4 0.1 17.8 9.1 19.3 87.5 PMP22 "CMT1A, GAS3, HMSNIA, HNPP, Sp110" ENSG00000109099 "Peripheral myelin protein 22" Q01453 17 15229773-15272292 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes, Charcot-Marie-Tooth disease, Deafness, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 404.1;Hofbauer cells: 558.3;Leydig cells: 324.3;Melanocytes: 343.3;Proximal enterocytes: 580.6;Skeletal myocytes: 288.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 32.2;eosinophil: 43.0;plasmacytoid DC: 23.8" "Group enriched" "Detected in many" 22 "dendritic cells: 23.8;granulocytes: 43.0" "Cell line enhanced" "Detected in many" "ASC diff: 383.5;HMC-1: 263.7;SuSa: 333.9;WM-115: 448.8" "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (3.00e-1)" "unprognostic (1.65e-1)" "unprognostic (2.21e-1)" "unprognostic (4.63e-1)" "unprognostic (5.57e-3)" "unprognostic (2.28e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-1)" "unprognostic (4.33e-2)" "unprognostic (7.70e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.83e-2)" "unprognostic (5.45e-2)" "unprognostic (2.88e-1)" "unprognostic (1.08e-2)" 275.6 45.4 113.6 55.1 161.0 4.9 184.5 153.2 140.7 192.2 77.9 212.2 41.7 142.1 36.5 68.2 163.4 106.5 167.6 113.5 129.0 53.5 11.7 208.4 27.8 163.3 144.2 102.9 22.8 10.8 26.3 201.9 159.9 81.2 74.7 6.5 77.5 80.6 252.4 112.7 239.1 122.0 135.0 27.9 96.2 20.7 141.1 17.3 95.3 127.0 21.8 208.9 157.4 216.7 7.0 44.1 61.9 62.2 383.5 167.1 12.6 60.5 68.8 58.7 38.0 48.7 1.1 0.1 7.0 172.3 22.7 0.7 74.0 1.1 15.4 0.2 13.9 4.3 76.7 17.2 201.8 0.1 263.7 126.9 1.1 32.6 1.8 72.1 66.1 2.8 24.5 0.8 33.2 6.1 0.2 2.0 3.5 4.0 74.7 22.0 39.3 0.0 44.6 4.8 0.1 40.6 16.6 0.6 134.2 333.9 0.2 0.5 81.4 12.7 45.7 216.9 62.0 0.5 0.1 0.3 84.7 0.1 448.8 32.2 1.4 43.0 0.0 0.9 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.1 0.2 0.1 0.2 23.8 0.0 0.9 113.6 161.0 153.2 140.7 113.5 129.0 163.3 144.2 159.9 135.0 141.1 216.7 86.6 28.9 11.5 50.9 2.8 90.1 6.7 6.1 9.6 1.4 43.0 82.7 68.4 4.3 7.4 0.0 0.0 8.8 2.5 9.1 3.9 4.5 17.7 20.1 118.6 148.0 4.8 10.1 3.7 3.3 23.1 404.1 2.6 11.0 119.7 25.0 88.5 0.9 558.3 0.0 1.8 23.8 0.0 23.4 116.8 11.0 324.3 93.0 343.3 29.0 11.8 61.6 0.0 46.8 217.1 1.7 25.2 246.4 1.9 4.9 580.6 0.7 3.0 2.2 230.1 288.8 141.1 3.0 4.8 3.0 103.0 19.0 8.7 49.2 17.9 5.2 PNLIP PL ENSG00000175535 "Pancreatic lipase" P16233 10 116545931-116567855 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2058 "pancreas: 444687.5" "Cell type enriched" "Detected in some" 8 "Exocrine glandular cells: 4086.8" "Cancer enriched" "Detected in some" 4854 "pancreatic cancer: 2731.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.3" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA062430, HPA062494" Enhanced "Secreted to digestive system" NA NA 14000000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "HPA062430: AB_2684761, HPA062494: AB_2684782" "unprognostic (2.05e-2)" "unprognostic (4.46e-2)" 13.8 3.1 0.0 10.5 0.0 1.1 8.9 0.0 0.0 7.2 0.0 3.8 64.8 9.1 0.4 4.8 1.5 0.0 78.2 0.0 0.0 3.0 10.2 2.1 16.9 0.0 0.0 216.0 444687.5 0.0 2.5 24.4 0.0 4.5 0.0 0.0 71.7 0.0 2.9 4.6 34.0 0.0 0.0 3.8 28.2 2.3 0.0 0.0 2.0 0.0 0.0 1.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.5 0.0 0.0 0.3 0.0 0.0 0.1 4086.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 14.5 0.0 0.0 0.5 0.1 507.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PNLIPRP1 PLRP1 ENSG00000187021 "Pancreatic lipase related protein 1" P54315 10 116590385-116609175 "Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2343 "pancreas: 10825.1" "Cell type enriched" "Detected in some" 10 "Exocrine glandular cells: 688.3" "Cancer enriched" "Detected in single" 476 "pancreatic cancer: 32.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/84: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA 340000 "Cluster 25: Pancreas - Digestion" "Cluster 16: U-266 - Nucleosome" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (1.21e-1)" "unprognostic (4.08e-3)" "unprognostic (1.40e-1)" "unprognostic (1.80e-1)" "unprognostic (2.76e-2)" "unprognostic (1.41e-1)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" 1.7 0.2 0.0 0.2 0.0 0.3 0.6 0.0 0.0 0.9 0.0 0.2 2.1 0.3 0.0 0.4 0.1 0.0 2.0 0.0 0.0 0.2 0.8 0.2 0.4 0.0 0.0 4.6 10825.1 0.0 0.5 0.8 0.0 0.4 0.1 0.0 2.7 0.0 0.2 0.4 1.1 0.0 0.0 0.4 1.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 688.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 3.4 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.1 66.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.3 PNLIPRP3 ENSG00000203837 "Pancreatic lipase related protein 3" Q17RR3 10 116427847-116477957 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 9.0;skin 1: 14.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.1;Early spermatids: 1.5;Late spermatids: 1.9;Melanocytes: 1.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "hTCEpi: 320.3" "Not detected" "Not detected" "HPA046202, HPA052009" Uncertain "Secreted - unknown location" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA046202: AB_10959739, HPA052009: AB_2681692" "unprognostic (2.62e-4)" "unprognostic (1.60e-1)" "unprognostic (6.97e-2)" 2.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 320.3 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 PNOC "N/OFQ, NOP, PPNOC" ENSG00000168081 Prepronociceptin Q13519 8 28316986-28343355 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Neuropeptide, Neurotransmitter, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.3;fallopian tube: 18.2;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in some" "B-cells: 61.5;dendritic cells: 12.6;Inhibitory neurons: 23.3;Melanocytes: 14.2;Plasma cells: 80.4" "Cancer enriched" "Detected in many" 8 "ovarian cancer: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "memory B-cell: 231.2;naive B-cell: 260.3;plasmacytoid DC: 194.0" "Group enriched" "Detected in many" 20 "B-cells: 260.3;dendritic cells: 194.0" "Group enriched" "Detected in some" 6 "Daudi: 38.3;Karpas-707: 29.2;RPMI-8226: 11.2;U-698: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044507, HPA056724" Enhanced "Secreted to blood" NA NA 12300 "Cluster 19: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA044507: AB_10795043, HPA056724: AB_2683216" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.94e-6)" "unprognostic (3.71e-2)" "unprognostic (5.16e-5)" "unprognostic (1.03e-1)" "unprognostic (1.50e-1)" "unprognostic (7.81e-4)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" "unprognostic (7.57e-9)" "unprognostic (2.19e-2)" "unprognostic (5.45e-1)" "unprognostic (3.44e-1)" "unprognostic (1.40e-1)" 0.2 0.8 5.4 9.9 5.1 2.7 0.6 1.3 10.8 0.2 1.3 2.9 4.3 0.1 0.0 0.6 18.2 1.1 0.1 2.9 9.9 0.7 0.2 1.0 25.1 10.4 6.3 0.4 0.0 0.0 0.0 0.0 9.9 0.2 1.5 0.0 1.6 0.1 0.0 0.1 5.8 0.5 14.3 14.4 3.2 0.6 4.3 2.7 0.4 0.0 23.6 3.7 0.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 4.0 4.4 23.0 0.1 0.1 0.0 0.2 11.5 2.3 0.2 7.7 0.1 231.2 0.2 0.1 1.1 260.3 0.1 0.1 1.3 1.2 3.2 194.0 0.5 11.1 5.4 5.1 1.3 10.8 2.9 9.9 10.4 6.3 9.9 14.3 4.3 3.0 0.1 0.0 1.9 1.3 61.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.4 0.4 0.2 0.0 23.3 0.1 0.0 0.0 0.3 2.8 0.3 1.7 14.2 1.0 3.0 0.0 1.0 0.0 0.9 0.1 0.0 0.0 80.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 0.0 0.0 1.1 0.0 0.3 0.5 PNP "NP, PUNP" ENSG00000198805 "Purine nucleoside phosphorylase" P00491 14 20468954-20477089 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 333.9;epididymis: 594.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 360.6;Erythroid cells: 227.3;Syncytiotrophoblasts: 646.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 531.3;U-937: 593.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001625 Enhanced Supported Cytosol NA NA 58000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA001625: AB_1854577" "unprognostic (1.20e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-2)" "unprognostic (1.70e-1)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (4.94e-3)" "unprognostic (3.87e-2)" "unprognostic (7.45e-2)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "prognostic favorable (2.24e-4)" "unprognostic (1.69e-1)" "unprognostic (7.54e-2)" "unprognostic (2.46e-1)" "unprognostic (1.64e-3)" 78.6 24.8 16.1 46.8 16.6 333.9 34.6 22.6 22.7 25.3 18.9 52.2 120.3 14.2 594.8 87.4 18.2 56.8 29.0 17.7 19.6 206.8 98.0 48.6 46.7 20.3 18.1 5.0 23.2 32.0 19.8 132.6 20.1 15.0 61.8 27.1 22.6 27.4 7.3 29.6 60.3 38.7 23.1 44.5 50.6 7.4 21.1 33.5 17.8 10.0 64.4 100.4 41.5 20.1 86.1 113.4 24.0 53.9 26.0 21.0 71.8 85.2 40.3 68.2 67.0 66.1 76.5 227.1 96.8 45.5 81.5 89.9 125.2 159.8 89.5 75.0 109.6 189.1 89.9 109.3 24.2 531.3 94.7 14.4 57.4 206.0 91.0 37.8 295.9 141.0 95.4 137.4 86.7 79.1 157.6 311.3 67.5 215.7 186.1 130.2 35.9 88.3 243.7 79.6 101.9 22.6 163.4 205.0 13.2 32.6 75.5 92.5 240.0 46.1 62.6 105.1 148.4 63.1 113.3 258.9 39.3 593.0 4.6 12.0 30.6 10.3 39.8 27.3 73.6 25.7 44.2 45.0 48.1 28.8 27.6 35.9 3.7 38.5 26.6 27.3 16.7 31.1 16.1 16.6 22.6 22.7 17.7 19.6 20.3 18.1 20.1 23.1 21.1 20.1 149.6 0.0 23.5 5.9 50.3 84.6 67.4 12.6 112.7 4.7 56.3 62.6 3.5 27.1 13.4 82.8 14.6 360.6 45.2 61.1 39.2 43.2 1.3 36.0 12.7 139.4 46.4 227.3 0.6 51.5 41.8 32.4 106.5 65.3 57.7 5.0 24.3 30.6 70.9 16.8 1.1 51.3 18.3 18.1 58.4 0.8 0.3 83.3 30.2 3.7 13.2 78.8 29.9 3.0 0.9 130.8 83.9 0.7 88.6 27.5 41.2 118.9 10.5 18.1 0.0 23.9 41.3 0.4 0.7 114.7 63.9 646.2 62.3 3.1 51.4 77.1 PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Fibroblasts: 123.5;Leydig cells: 268.7;Peritubular cells: 261.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "ASC diff: 23.0;BJ: 39.2;fHDF/TERT166: 23.9;HHSteC: 94.1;U-2197: 46.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 910000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.69e-2)" "unprognostic (4.73e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.65e-1)" "unprognostic (1.90e-3)" "unprognostic (1.71e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.02e-5)" "unprognostic (5.91e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.02e-2)" 191.0 14.3 9.1 13.3 8.2 0.2 116.3 6.4 8.7 106.1 7.1 76.1 11.6 105.1 19.7 36.1 127.5 103.8 87.1 6.8 8.1 5.2 12.5 66.3 3.8 7.3 10.3 178.0 20.8 2.9 19.5 18.1 8.2 69.8 8.2 0.6 48.8 34.4 20.2 45.4 26.1 44.7 6.7 3.3 75.5 26.9 10.3 10.8 71.5 30.5 2.7 101.3 87.9 6.7 0.0 0.0 0.0 0.0 23.0 3.1 0.1 39.2 5.3 0.4 0.3 0.0 0.0 0.0 0.6 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.1 0.0 0.0 14.9 0.0 0.9 0.0 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.8 9.1 8.2 6.4 8.7 6.8 8.1 7.3 10.3 8.2 6.7 10.3 6.7 8.5 0.0 3.3 0.0 0.0 6.4 0.4 0.0 0.6 0.5 0.8 0.9 1.7 1.5 0.6 0.0 0.0 0.4 1.3 0.0 0.0 0.0 1.6 0.3 11.2 3.8 0.0 0.0 0.0 0.0 0.4 123.5 2.6 0.3 0.0 0.7 4.2 0.1 0.6 0.0 1.9 0.0 0.0 0.3 8.8 9.2 268.7 1.3 5.4 6.5 0.0 0.3 3.1 5.5 0.2 0.0 0.0 261.1 1.6 0.5 0.1 0.0 0.0 0.5 0.0 4.4 16.0 0.7 0.6 0.7 6.0 0.5 1.6 0.0 0.0 0.2 PODNL1 "FLJ23447, SLRR5B" ENSG00000132000 "Podocan like 1" Q6PEZ8 19 13931187-13953392 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 13.4;Bipolar cells: 38.7;Leydig cells: 18.3;Peritubular cells: 38.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 6.6;HSkMC: 11.6;hTERT-RPE1: 18.8;SiHa: 9.7;U-2 OS: 6.7" "Not detected" "Not detected" "Region enriched" "Detected in some" 11 "spinal cord: 18.9" HPA042807 Approved "Secreted - unknown location" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "HPA042807: AB_10795514" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (8.08e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.61e-8)" "unprognostic (1.78e-1)" "unprognostic (1.86e-2)" "unprognostic (3.68e-1)" "unprognostic (2.02e-1)" "unprognostic (3.08e-3)" "unprognostic (4.37e-2)" "unprognostic (1.01e-1)" "unprognostic (0.00e+0)" "unprognostic (3.94e-3)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (4.49e-4)" 1.8 0.7 1.9 0.9 1.7 0.5 4.9 2.3 1.8 5.6 0.8 2.8 0.4 1.5 0.2 8.2 2.1 1.3 4.7 1.2 3.6 1.7 0.5 5.1 0.2 4.3 4.4 3.3 1.5 0.1 5.1 3.7 3.0 7.9 0.3 2.0 5.3 0.9 1.6 11.4 2.3 0.5 3.1 1.0 1.7 7.2 3.7 0.0 3.1 1.3 0.2 2.7 12.0 2.0 0.3 0.4 0.4 0.2 0.6 1.5 0.1 4.1 2.4 0.8 1.6 0.3 0.4 0.2 0.3 6.6 0.2 1.6 0.1 0.1 0.4 1.5 0.6 0.8 0.4 0.0 5.1 0.2 0.5 11.6 0.7 1.1 0.1 18.8 0.0 0.1 0.4 0.3 1.6 2.7 0.2 0.2 0.1 0.3 0.4 0.1 0.1 0.0 0.3 0.0 0.7 0.4 9.7 0.1 0.3 0.4 0.1 0.5 0.7 2.0 6.7 0.5 0.2 0.3 0.0 0.1 0.8 0.9 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.9 1.7 2.3 1.8 1.2 3.6 4.3 4.4 3.0 3.1 3.7 2.0 1.4 0.0 0.5 2.3 0.0 1.3 0.9 13.4 0.0 38.7 2.1 8.0 1.6 0.0 1.4 0.0 2.1 0.4 0.2 1.8 0.0 0.2 1.7 0.5 6.1 0.9 0.0 2.7 0.5 0.0 0.2 4.7 0.0 0.4 0.0 0.5 0.7 0.1 9.8 1.7 0.7 1.1 0.0 1.2 1.7 2.1 18.3 0.9 1.8 1.9 0.0 1.8 0.0 1.5 0.3 0.6 9.0 38.0 0.0 0.5 0.6 0.1 1.4 4.6 0.0 0.6 1.0 1.0 0.7 2.6 4.3 0.8 0.2 0.1 1.4 1.6 POFUT1 "FUT12, KIAA0180, O-Fuc-T, O-FUT" ENSG00000101346 "Protein O-fucosyltransferase 1" Q9H488 20 32207880-32238658 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism, Notch signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 20.9" "Lineage enriched" "Detected in all" 5 "monocytes: 20.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054519, HPA059935" Approved Approved Centrosome "Intracellular and membrane" NA NA 60000 "Cluster 51: Monocytes - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Centrosome "HPA054519: AB_2682515, HPA059935: AB_2684171" "unprognostic (6.61e-2)" "unprognostic (4.10e-3)" "unprognostic (8.83e-2)" "unprognostic (5.51e-3)" "unprognostic (6.90e-2)" "unprognostic (1.62e-1)" "unprognostic (4.65e-1)" "unprognostic (8.51e-2)" "unprognostic (1.84e-1)" "unprognostic (5.57e-2)" "unprognostic (3.01e-1)" "unprognostic (2.19e-1)" "unprognostic (6.76e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.03e-2)" "unprognostic (5.86e-3)" 17.6 10.8 7.9 11.7 8.4 10.5 16.5 7.2 7.7 15.2 9.1 20.0 20.4 14.9 14.4 12.4 20.4 11.4 17.5 7.7 7.3 16.1 30.9 12.2 9.1 9.3 8.3 20.0 13.8 23.8 9.1 16.4 8.0 14.5 19.1 5.9 13.0 18.1 12.8 13.7 24.0 18.1 8.0 9.4 11.1 9.5 8.1 10.5 18.9 14.0 10.0 14.0 10.9 8.2 47.1 37.2 31.5 34.7 52.9 51.4 58.8 47.8 56.2 78.8 51.3 111.9 62.1 31.7 69.8 53.5 87.2 51.2 30.5 59.0 68.0 16.5 19.2 47.1 32.1 51.2 41.2 41.0 28.9 45.4 45.7 59.7 38.8 33.5 44.6 30.0 36.3 17.6 55.6 23.1 28.4 31.4 16.2 45.2 59.4 23.3 83.6 29.5 24.2 30.7 20.6 26.5 109.5 30.0 41.0 24.0 44.7 48.5 38.8 113.4 42.2 71.8 82.4 21.4 29.3 28.7 68.5 139.9 73.0 4.3 5.4 2.6 3.2 15.1 3.6 3.2 2.8 3.0 4.6 2.6 3.6 2.5 1.0 2.0 20.9 3.4 3.3 4.2 7.9 8.4 7.2 7.7 7.7 7.3 9.3 8.3 8.0 8.0 8.1 8.2 7.8 9.6 9.5 11.1 5.2 2.9 4.7 8.6 5.2 3.1 7.2 7.1 13.4 8.6 7.9 7.3 2.1 15.2 5.7 17.5 1.9 10.0 0.9 7.1 10.8 9.3 12.0 9.2 9.0 10.4 28.2 12.0 9.2 13.6 5.1 13.1 13.9 39.8 10.7 8.4 9.0 13.4 2.0 8.1 3.8 1.7 10.5 6.5 5.4 6.5 9.3 5.2 3.1 11.1 9.6 9.6 11.9 14.3 8.2 6.7 31.7 5.3 7.2 4.3 13.1 11.1 9.4 2.9 7.3 9.7 1.7 7.7 5.0 26.0 19.0 4.1 POFUT2 "C21orf80, FUT13, KIAA0958" ENSG00000186866 "Protein O-fucosyltransferase 2" Q9Y2G5 21 45263928-45287898 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 95.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044297 Uncertain "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA044297: AB_10965176" "unprognostic (1.32e-2)" "unprognostic (1.65e-3)" "prognostic unfavorable (4.55e-7)" "unprognostic (1.49e-2)" "unprognostic (4.09e-3)" "unprognostic (5.03e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (2.62e-1)" "unprognostic (2.15e-1)" "unprognostic (4.16e-2)" "unprognostic (4.20e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.66e-12)" "unprognostic (1.56e-2)" "unprognostic (2.53e-1)" "unprognostic (3.91e-3)" "unprognostic (5.25e-2)" 15.7 20.7 9.4 8.5 9.6 14.0 14.1 9.5 10.9 20.2 21.2 17.3 9.7 16.1 8.9 8.6 20.4 10.3 16.6 9.6 13.8 19.6 20.5 16.1 7.7 11.9 12.1 27.7 19.0 8.2 31.4 16.8 11.8 19.1 6.3 8.6 14.5 10.3 7.8 8.6 15.0 12.0 9.6 16.9 15.3 17.6 13.7 5.3 22.2 5.1 6.5 15.9 13.9 9.6 10.4 11.2 22.1 24.5 39.3 36.1 10.3 57.1 45.4 25.9 38.7 24.0 17.2 7.2 41.9 95.1 58.5 10.4 13.1 22.9 27.9 12.1 15.2 14.4 17.4 18.8 45.4 10.7 18.4 25.6 14.7 32.4 17.7 84.5 25.6 9.5 13.5 11.6 27.4 10.7 5.3 17.7 27.6 17.3 15.7 10.8 6.6 9.1 14.4 9.4 9.6 14.0 33.6 20.3 21.1 24.6 14.8 15.4 28.5 19.5 19.0 30.2 25.8 27.7 15.4 5.5 39.9 13.2 30.8 0.3 0.3 0.8 0.3 0.3 0.5 0.2 0.3 0.2 0.1 0.2 0.4 0.4 0.5 0.3 0.3 0.4 0.3 0.3 9.4 9.6 9.5 10.9 9.6 13.8 11.9 12.1 11.8 9.6 13.7 9.6 12.4 6.4 9.6 19.6 10.7 6.6 7.0 6.8 6.2 6.9 11.8 9.5 8.7 11.5 7.0 12.9 10.4 9.0 14.7 7.4 3.9 7.6 34.9 29.4 17.5 8.7 10.1 7.4 6.8 6.2 13.5 19.8 13.3 15.9 7.0 20.4 10.0 8.6 6.9 5.0 9.9 14.7 4.1 4.8 8.8 51.2 14.6 8.1 8.8 7.5 8.0 10.2 3.1 11.1 7.6 8.0 7.5 13.9 12.4 7.3 6.6 3.9 30.6 14.5 0.0 14.5 17.5 20.1 5.2 4.5 4.0 13.5 12.3 12.2 7.8 7.9 POGLUT1 "9630046K23Rik, C3orf9, hCLP46, KDELCL1, KTELC1, MDS010, MDSRP, MGC32995, Rumi" ENSG00000163389 "Protein O-glucosyltransferase 1" Q8NBL1 3 119468963-119494708 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Gastrulation "Developmental protein, Glycosyltransferase, Transferase" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 81.2;monocytes: 151.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037855, HPA037856" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Endoplasmic reticulum" "HPA037855: AB_10672728, HPA037856: AB_2732477" "unprognostic (2.43e-1)" "unprognostic (5.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.83e-2)" "unprognostic (5.62e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-1)" "unprognostic (2.81e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-1)" "unprognostic (6.52e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (7.02e-7)" "unprognostic (3.08e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-3)" "prognostic favorable (2.23e-4)" 6.8 7.2 5.9 7.8 6.1 3.1 7.7 6.0 8.2 7.1 6.9 6.8 4.2 9.0 7.8 5.6 6.0 4.7 5.9 5.9 7.2 5.7 6.6 5.6 10.8 6.6 6.5 5.5 7.9 9.5 4.9 8.2 6.6 5.4 7.2 4.2 4.6 11.6 3.2 10.0 7.8 10.4 6.1 9.0 5.4 2.5 7.2 9.7 5.6 3.4 10.8 8.5 6.3 6.7 10.8 7.1 11.7 13.1 29.5 16.8 8.6 16.7 16.7 12.3 18.4 11.5 6.9 16.5 22.2 21.4 10.6 11.9 15.9 16.8 20.4 14.4 10.6 19.3 11.1 12.9 19.1 21.3 21.7 17.5 9.6 13.3 18.0 15.7 15.5 11.2 10.5 19.7 13.9 10.9 12.5 20.7 12.4 18.6 13.8 12.2 12.2 24.0 11.6 13.9 12.7 20.0 8.1 4.9 13.4 11.7 13.2 17.8 19.7 13.1 8.0 3.8 8.9 27.1 25.2 21.7 11.1 20.6 18.8 2.9 16.4 13.9 16.2 15.7 18.7 13.9 18.2 17.0 20.7 10.1 21.1 20.0 1.2 29.5 10.8 11.5 22.3 15.0 5.9 6.1 6.0 8.2 5.9 7.2 6.6 6.5 6.6 6.1 7.2 6.7 19.1 0.0 6.2 11.4 15.7 16.8 7.3 17.4 16.5 13.6 9.7 8.5 5.2 14.3 10.1 20.2 6.2 10.6 17.1 5.2 0.0 6.9 0.7 5.5 19.3 16.1 9.5 8.4 32.7 5.3 14.7 14.5 9.2 7.0 17.7 11.3 13.6 12.5 8.4 5.0 31.6 11.7 22.4 11.9 81.2 0.2 8.7 16.6 12.4 6.5 151.4 10.3 21.6 23.6 25.8 5.0 8.3 17.0 14.1 8.0 8.5 6.0 6.5 13.0 13.1 16.7 13.4 1.5 1.5 13.9 14.9 6.6 15.5 17.4 13.9 5.9 POGLUT2 "EP58, KDELC1, MGC5302" ENSG00000134901 "Protein O-glucosyltransferase 2" Q6UW63 13 102784281-102798976 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.0;Extravillous trophoblasts: 23.3;Fibroblasts: 3.8;Hofbauer cells: 3.3;Syncytiotrophoblasts: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.9" "Group enriched" "Detected in many" 5 "NK-cells: 3.9;T-cells: 2.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020780, HPA043946, HPA064398" Approved Supported Nucleoplasm "Intracellular and membrane" NA NA 44000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB020780: , HPA043946: AB_2678743, HPA064398: AB_2685256" "unprognostic (1.97e-2)" "unprognostic (2.34e-1)" "unprognostic (3.21e-1)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (6.68e-3)" "prognostic unfavorable (4.81e-4)" "unprognostic (4.34e-3)" "unprognostic (2.75e-2)" "unprognostic (7.26e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.11e-2)" "unprognostic (1.17e-1)" "unprognostic (2.46e-1)" "unprognostic (2.60e-3)" 4.6 2.3 1.5 3.1 2.2 1.6 3.3 2.2 2.4 5.6 1.6 3.5 1.3 11.1 4.3 2.6 4.3 8.1 4.8 1.5 1.5 4.6 7.7 3.4 2.4 1.8 1.7 6.5 1.6 2.8 2.1 12.2 1.9 2.7 2.7 3.4 1.8 4.2 0.8 2.3 2.1 12.5 1.7 3.6 2.4 1.5 1.9 1.9 2.9 2.5 1.9 6.0 3.2 2.7 8.1 6.0 36.8 35.5 37.0 28.5 9.0 21.4 16.4 19.5 33.5 17.1 11.5 0.0 16.7 17.6 10.0 13.3 26.6 10.9 19.5 3.4 22.1 9.8 16.3 18.8 32.1 25.4 34.5 27.0 12.3 14.8 14.2 29.1 43.0 12.3 16.3 0.0 10.5 9.0 11.4 20.8 23.5 11.5 17.9 0.0 26.3 9.5 53.7 0.7 5.5 33.7 21.0 5.6 12.3 30.5 16.1 10.9 13.3 12.8 9.3 14.7 21.6 7.4 14.4 0.0 25.2 0.0 22.6 0.0 0.0 0.0 1.4 0.0 2.4 0.2 0.7 1.1 0.6 0.0 0.2 0.7 0.0 3.9 0.0 0.0 0.9 0.2 1.5 2.2 2.2 2.4 1.5 1.5 1.8 1.7 1.9 1.7 1.9 2.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 6.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 23.3 3.8 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498384 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 6.8;Cardiomyocytes: 13.1;Cytotrophoblasts: 27.6;Extravillous trophoblasts: 14.5;Fibroblasts: 14.7;Hofbauer cells: 18.0;Syncytiotrophoblasts: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" 24.6 13.2 5.0 17.3 5.0 7.6 16.2 4.6 5.4 33.6 7.0 16.8 9.4 35.0 27.3 21.0 23.0 21.7 15.2 4.2 5.9 15.6 13.2 16.0 10.4 5.5 6.1 36.5 8.3 25.2 5.4 32.7 5.4 28.4 16.9 5.8 13.9 28.4 5.5 13.7 11.2 37.1 5.3 12.4 11.3 5.8 5.5 16.4 12.1 13.9 9.5 22.5 18.8 6.0 10.9 12.4 46.5 47.8 76.5 88.5 44.8 47.0 43.7 66.0 71.1 58.9 78.1 0.1 28.6 61.6 73.1 7.9 35.6 1.2 69.3 19.4 27.4 18.1 12.1 27.2 30.8 47.7 0.2 51.1 14.6 35.0 1.0 40.1 56.6 0.3 41.5 0.3 101.0 7.9 30.9 27.2 20.3 11.5 34.8 1.5 72.5 0.2 12.3 30.3 9.7 29.5 89.1 6.2 13.3 21.4 42.3 18.0 56.8 127.0 24.9 10.8 49.7 0.4 0.1 0.3 32.6 48.9 103.1 0.1 0.1 0.0 2.0 0.7 1.7 0.2 1.0 1.7 0.5 0.3 1.0 1.5 0.1 1.9 0.4 1.0 0.9 0.5 5.0 5.0 4.6 5.4 4.2 5.9 5.5 6.1 5.4 5.3 5.5 6.0 6.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 27.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 14.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 21.2 0.5 0.0 0.0 0.0 POM121 "DKFZP586G1822, DKFZP586P2220, KIAA0618, POM121A" ENSG00000196313 "POM121 transmembrane nucleoporin" Q96HA1 7 72879365-72951440 "Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 98.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB003710, HPA043809, HPA049817" Approved Enhanced "Nucleoplasm,Nuclear membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear membrane" "CAB003710: , HPA043809: AB_2678680, HPA049817: AB_2680896" "unprognostic (2.33e-1)" "unprognostic (3.05e-2)" "unprognostic (9.71e-2)" "unprognostic (5.86e-3)" "unprognostic (1.70e-1)" "unprognostic (2.06e-1)" "unprognostic (1.40e-1)" "unprognostic (6.38e-2)" "unprognostic (7.07e-3)" "unprognostic (3.08e-2)" "unprognostic (3.84e-2)" "unprognostic (1.71e-1)" "unprognostic (1.85e-1)" "unprognostic (3.66e-2)" "unprognostic (2.39e-1)" "unprognostic (7.43e-3)" "unprognostic (2.40e-1)" 25.4 20.4 10.3 18.8 10.1 44.7 21.0 7.2 14.3 18.3 3.4 19.5 21.6 19.6 9.4 20.1 18.7 13.6 16.0 11.9 9.7 16.6 23.5 17.4 21.3 6.8 8.5 23.8 25.5 16.1 21.4 17.0 6.4 19.2 12.1 17.5 19.3 11.2 25.7 21.6 22.8 13.0 2.3 22.9 21.8 18.7 8.8 17.8 20.0 16.0 17.1 18.8 18.1 9.1 49.6 35.4 43.5 98.0 23.0 18.8 36.0 34.6 29.2 33.8 29.3 63.0 30.6 67.7 11.0 30.1 37.5 37.0 43.5 33.6 37.6 59.2 86.5 50.6 36.6 42.4 23.5 106.1 61.8 24.8 23.3 44.9 41.0 21.9 25.5 38.5 141.2 49.3 33.7 37.8 63.7 67.0 45.5 27.4 42.3 57.4 33.8 57.1 17.2 42.8 61.7 54.3 30.3 57.3 31.1 28.8 48.1 55.0 36.2 60.2 36.8 48.0 70.5 58.8 58.8 96.0 35.2 66.6 61.0 0.0 0.8 1.4 1.7 0.5 1.0 1.0 1.1 1.3 0.9 1.1 0.9 1.4 0.9 1.6 1.4 1.5 0.6 1.1 10.3 10.1 7.2 14.3 11.9 9.7 6.8 8.5 6.4 2.3 8.8 9.1 31.8 38.5 28.9 33.0 28.6 25.2 10.1 17.5 29.0 34.6 19.5 19.7 4.4 20.0 19.9 18.4 98.0 17.1 30.6 19.7 5.9 12.3 13.2 14.6 24.7 18.3 18.0 30.7 55.6 17.1 13.2 19.2 32.1 21.3 16.5 31.1 17.2 24.9 16.2 40.4 58.9 21.7 16.2 18.9 21.7 6.3 14.9 23.3 19.6 23.4 13.8 18.2 32.0 30.2 38.6 21.8 14.1 17.7 37.6 22.2 19.1 8.4 17.6 26.6 13.1 27.0 17.6 19.2 13.1 29.6 31.0 19.4 27.9 24.7 23.2 21.9 POM121C ENSG00000272391 "POM121 transmembrane nucleoporin C" A8CG34 7 75416786-75486299 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA043809, HPA049817" Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear membrane" "HPA043809: AB_2678680, HPA049817: AB_2680896" "unprognostic (9.11e-2)" "unprognostic (1.27e-1)" "unprognostic (2.85e-1)" "unprognostic (1.44e-1)" "unprognostic (3.51e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (4.27e-2)" "unprognostic (4.97e-2)" "unprognostic (1.08e-1)" "unprognostic (5.84e-3)" "unprognostic (2.03e-1)" "unprognostic (5.06e-2)" "unprognostic (2.40e-1)" "unprognostic (2.35e-1)" "unprognostic (1.44e-2)" "unprognostic (4.00e-2)" 14.9 14.0 3.5 15.5 3.8 28.9 14.2 8.0 9.3 13.8 2.4 14.2 12.0 16.6 9.0 15.9 14.1 12.0 13.9 7.0 4.9 13.1 13.2 12.9 18.2 2.2 3.1 18.7 18.1 16.8 13.4 16.4 2.0 13.0 12.9 26.3 14.3 11.5 19.6 17.7 14.0 15.1 0.3 15.5 14.0 12.5 5.2 17.6 16.7 10.7 19.9 14.3 14.3 5.5 41.8 34.1 46.3 89.0 17.1 19.0 30.4 29.7 27.3 23.7 22.8 41.2 26.5 73.4 12.0 32.6 37.2 36.7 39.6 36.7 38.9 49.9 55.1 36.4 39.6 27.8 22.5 97.0 49.5 16.2 22.8 36.3 26.8 34.5 24.6 29.9 103.8 39.8 38.9 41.8 59.5 49.3 36.9 32.0 38.4 53.0 30.7 37.6 13.1 56.0 51.4 67.4 34.3 54.0 23.8 41.5 47.1 34.2 27.4 57.4 30.6 42.2 62.3 42.4 54.4 88.2 37.3 49.1 53.9 0.2 0.4 0.5 1.1 0.5 1.0 0.8 0.9 0.3 0.3 1.0 0.5 0.6 1.2 0.9 0.3 1.1 0.2 0.6 3.5 3.8 8.0 9.3 7.0 4.9 2.2 3.1 2.0 0.3 5.2 5.5 23.1 35.3 26.2 29.4 27.8 18.0 11.8 13.4 33.6 30.7 21.3 23.4 12.6 21.5 21.4 12.9 68.8 13.4 27.2 12.3 5.9 11.8 2.1 14.2 21.3 20.7 28.7 33.9 59.2 17.1 10.2 21.0 31.6 18.3 7.6 28.6 16.8 15.1 12.0 25.2 60.2 17.4 14.2 16.4 15.8 3.8 18.0 21.7 7.2 35.6 17.1 21.3 37.0 28.1 45.6 18.8 8.0 15.4 37.8 24.6 10.0 9.6 18.7 29.4 13.1 26.1 17.4 19.2 12.4 32.9 18.5 17.0 34.0 22.0 17.0 19.7 POMC "ACTH, CLIP, LPH, MSH, NPP, POC" ENSG00000115138 Proopiomelanocortin P01189 2 25160853-25168903 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Endorphin, Hormone" "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 903 "pituitary gland: 34360.0" "Cell type enhanced" "Detected in many" "Early spermatids: 119.8;Late spermatids: 352.6;Spermatocytes: 83.0" "Cancer enriched" "Detected in many" 6 "testis cancer: 18.5" "Group enriched" "Detected in all" 6 "hypothalamus: 38.0;thalamus: 13.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;THP-1: 2.1" "Region enriched" "Detected in all" 7 "hypothalamus: 44.0" "Region enriched" "Detected in all" 5 "hypothalamus: 88.1" "CAB002762, HPA046135, HPA063644, CAB079881" Enhanced "Secreted to blood" NA NA 380000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "CAB002762: , CAB079881: , HPA046135: AB_2679552, HPA063644: AB_2685071" "unprognostic (8.02e-2)" "unprognostic (1.47e-2)" "unprognostic (4.78e-2)" "unprognostic (1.96e-3)" "unprognostic (3.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (4.30e-2)" "unprognostic (8.74e-3)" "unprognostic (1.38e-1)" "prognostic favorable (5.70e-4)" "unprognostic (8.02e-2)" "unprognostic (4.29e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (1.37e-3)" "unprognostic (3.84e-2)" 6.1 19.1 2.7 1.2 2.8 1.1 3.5 3.2 4.4 3.0 2.2 6.9 0.4 3.1 0.3 13.7 2.2 0.2 12.1 2.3 38.0 4.9 12.9 3.5 1.1 4.5 3.3 5.0 22.6 0.1 34360.0 1.2 3.7 5.0 0.0 0.2 5.8 0.3 5.7 35.7 4.8 0.1 4.0 11.1 15.5 25.7 13.1 1.2 8.4 5.2 0.4 2.5 3.7 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 12.6 8.6 11.5 13.2 9.1 16.8 8.8 11.3 15.9 17.4 11.6 12.6 3.8 18.2 8.0 27.9 10.5 9.7 2.7 2.8 3.2 4.4 2.3 38.0 4.5 3.3 3.7 4.0 13.1 3.5 22.3 0.0 2.2 1.0 16.1 4.5 2.2 6.9 2.2 2.6 6.1 6.7 2.5 2.8 2.5 0.0 0.0 0.5 24.4 0.2 15.6 7.8 119.8 0.6 4.9 11.6 0.0 28.8 0.3 17.3 6.0 5.2 4.6 0.6 7.0 9.7 15.4 2.0 34.5 6.7 0.6 0.0 6.1 10.9 7.9 352.6 4.7 17.2 17.8 1.9 8.5 11.5 15.5 0.0 0.3 10.1 1.1 13.2 17.8 4.1 0.1 3.9 0.7 7.5 13.1 4.6 3.8 83.0 27.3 1.6 5.5 0.4 14.9 12.9 0.6 3.8 POMT1 LGMD2K ENSG00000130714 "Protein O-mannosyltransferase 1" Q9Y6A1 9 131502789-131523806 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 64.5;Spermatocytes: 71.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065252 Uncertain "Golgi apparatus" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" "HPA065252: AB_2685445" "unprognostic (2.00e-3)" "unprognostic (2.02e-1)" "unprognostic (1.60e-1)" "unprognostic (5.09e-3)" "unprognostic (1.67e-1)" "unprognostic (7.97e-2)" "unprognostic (5.35e-3)" "unprognostic (1.14e-1)" "unprognostic (9.76e-3)" "unprognostic (2.84e-1)" "prognostic favorable (3.90e-5)" "unprognostic (8.36e-2)" "prognostic favorable (4.68e-5)" "unprognostic (2.41e-2)" "unprognostic (1.61e-1)" "unprognostic (4.72e-2)" "unprognostic (2.12e-1)" 15.7 20.9 16.6 7.6 16.7 6.6 16.2 18.4 21.0 21.1 15.0 24.8 9.0 17.1 7.2 15.2 18.4 9.3 24.5 25.5 16.0 25.5 24.4 15.6 8.3 16.0 16.2 25.6 25.9 15.5 31.3 9.7 16.5 28.4 6.5 8.1 20.1 8.7 32.9 17.5 19.9 7.1 14.2 22.2 20.4 63.7 16.9 7.1 19.0 13.4 5.4 16.5 17.1 15.5 9.8 17.4 10.5 26.4 19.3 13.5 24.5 12.1 17.0 21.3 14.1 15.8 14.7 2.5 16.9 26.4 8.6 24.1 17.3 16.6 5.9 16.2 21.6 4.2 28.5 7.8 23.1 13.1 10.5 10.8 10.0 12.3 5.0 17.6 15.1 16.4 13.4 15.6 23.2 27.6 15.8 25.2 6.7 9.6 21.1 15.7 13.8 24.6 18.1 1.5 15.0 14.1 25.1 26.8 13.0 5.8 31.4 17.7 20.9 13.8 2.2 28.6 10.3 7.3 7.0 5.2 8.7 29.1 13.0 0.0 2.8 3.4 5.2 3.0 7.7 1.9 5.0 5.3 4.0 2.6 4.8 3.6 0.6 3.2 2.9 2.4 5.2 4.0 16.6 16.7 18.4 21.0 25.5 16.0 16.0 16.2 16.5 14.2 16.9 15.5 5.9 9.6 16.0 18.6 7.1 4.5 4.9 7.2 5.7 13.2 7.8 8.6 9.7 10.0 8.7 12.9 8.4 20.8 6.5 12.9 1.9 10.7 64.5 9.6 7.3 8.0 7.8 1.3 21.5 6.7 12.9 9.0 9.2 9.9 2.5 15.1 11.0 10.1 10.8 21.9 25.9 8.4 10.2 5.4 5.9 33.0 8.7 5.6 5.4 15.9 7.5 12.3 5.2 18.6 11.1 8.1 6.0 10.1 6.8 4.9 14.2 7.5 6.8 16.6 6.6 7.5 7.2 71.6 9.6 5.7 3.0 17.5 9.0 6.2 9.1 2.6 PON1 "ESA, PON" ENSG00000005421 "Paraoxonase 1" P27169 7 95297676-95324532 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 103 "liver: 531.8" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 440.0" "Cancer enriched" "Detected in some" 78 "liver cancer: 97.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001610 Approved "Secreted to blood" NA NA 96000000000 17000000000 "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" "HPA001610: AB_1079656" "unprognostic (2.02e-2)" "unprognostic (2.41e-2)" "unprognostic (3.04e-1)" "unprognostic (3.54e-2)" "unprognostic (2.70e-1)" "prognostic favorable (7.24e-7)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (9.02e-3)" "unprognostic (1.76e-3)" "unprognostic (3.97e-2)" "unprognostic (6.74e-9)" "unprognostic (1.09e-3)" "unprognostic (2.29e-2)" "unprognostic (2.07e-1)" "unprognostic (5.54e-3)" 0.0 4.1 0.6 0.0 0.5 0.0 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.5 0.6 0.2 531.8 0.1 0.0 0.5 0.5 0.6 0.1 0.0 0.8 0.0 0.5 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.3 0.6 5.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.6 0.6 0.5 0.6 0.5 0.5 0.5 0.3 0.6 0.6 0.0 0.0 1.5 7.2 1.1 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.6 18.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.4 3.0 13.5 0.2 0.2 0.0 0.2 0.0 0.3 0.0 0.1 8.9 440.0 0.0 0.0 0.2 0.2 0.0 13.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 1.6 0.5 0.4 0.2 0.0 0.1 0.0 0.6 0.5 0.3 0.1 PON2 ENSG00000105854 "Paraoxonase 2" Q15165 7 95404862-95435329 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 258.9" "Cell type enhanced" "Detected in many" "Astrocytes: 341.5;Extravillous trophoblasts: 300.9;Skeletal myocytes: 284.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 33.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025430, HPA029193" Enhanced "Secreted to blood" NA NA 160000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025430: , HPA029193: AB_10602148" "unprognostic (1.43e-1)" "prognostic unfavorable (1.43e-5)" "unprognostic (3.80e-1)" "unprognostic (4.14e-1)" "unprognostic (3.89e-2)" "unprognostic (3.77e-3)" "unprognostic (1.19e-3)" "unprognostic (9.87e-3)" "unprognostic (9.54e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.80e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (1.40e-1)" "unprognostic (6.43e-2)" "unprognostic (7.99e-3)" "unprognostic (2.56e-1)" 50.6 129.9 196.0 22.7 206.2 10.9 62.6 184.9 258.9 43.3 150.1 69.0 81.6 45.9 61.2 28.6 41.3 53.3 45.5 192.1 209.8 56.5 183.7 105.4 14.3 183.6 197.1 31.6 26.8 28.4 49.8 98.3 186.0 39.5 86.0 30.2 29.9 45.6 15.4 56.6 51.0 51.5 182.0 22.3 27.6 28.3 197.9 13.9 37.7 17.5 33.0 37.6 30.3 205.7 51.1 313.4 250.6 137.2 34.2 74.5 69.6 101.5 118.7 77.3 83.7 72.1 113.8 0.0 138.4 100.9 148.2 33.3 46.2 78.3 87.4 0.8 59.8 25.9 186.3 238.1 53.9 0.1 34.1 108.6 88.7 41.7 56.5 157.8 162.7 0.0 16.9 1.0 231.1 46.6 0.1 29.2 49.2 135.4 71.4 0.0 117.5 12.5 239.4 39.4 17.2 53.5 144.7 159.8 102.9 142.7 47.3 17.0 178.3 115.7 83.7 39.6 100.2 26.2 32.5 0.4 108.1 23.9 154.3 0.0 7.8 0.8 5.0 4.3 4.5 1.6 1.9 4.5 33.8 0.5 2.5 3.5 0.0 8.9 2.3 8.1 1.1 4.4 196.0 206.2 184.9 258.9 192.1 209.8 183.6 197.1 186.0 182.0 197.9 205.7 65.7 128.2 104.3 341.5 4.6 16.8 42.8 201.4 25.6 5.6 51.0 37.6 39.4 67.2 178.5 84.6 0.0 75.6 13.9 121.4 9.8 149.9 5.5 29.9 32.0 86.5 12.6 26.1 0.7 50.6 300.9 36.3 20.4 57.0 14.5 55.2 44.3 151.7 40.5 38.7 1.8 36.3 173.0 20.8 63.7 2.6 16.1 27.4 112.1 72.1 17.4 185.0 10.3 126.2 149.2 75.7 102.2 21.8 4.9 25.7 85.7 55.8 64.6 8.2 19.7 284.5 49.2 2.6 7.5 25.4 16.1 50.3 8.1 44.5 81.0 23.4 PON3 ENSG00000105852 "Paraoxonase 3" Q15166 7 95359872-95396375 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 616.7" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 509.6" "Group enriched" "Detected in many" 9 "liver cancer: 30.8;lung cancer: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 28.9;CACO-2: 8.6;CAPAN-2: 6.5;Hep G2: 32.6;T-47d: 17.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA014848, CAB025250" Enhanced "Secreted to blood" NA NA 1760000000 380000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB025250: , HPA014848: AB_1855540" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.28e-3)" "unprognostic (5.52e-3)" "unprognostic (1.36e-1)" "unprognostic (4.87e-1)" "unprognostic (1.44e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (6.44e-3)" "unprognostic (9.14e-2)" "unprognostic (7.18e-3)" "unprognostic (8.30e-9)" "unprognostic (1.66e-1)" "unprognostic (1.04e-2)" "unprognostic (8.29e-2)" "unprognostic (5.12e-2)" 1.4 3.8 2.1 0.5 2.0 0.0 31.2 1.7 1.9 5.3 1.4 2.0 7.9 0.9 3.6 0.5 1.3 4.4 1.0 1.8 2.1 2.7 616.7 14.2 0.1 2.3 2.2 12.4 14.3 0.2 24.9 0.8 2.9 0.9 2.8 0.1 26.3 3.9 0.3 7.4 3.1 0.2 2.1 0.3 2.3 9.0 2.1 1.6 7.1 0.3 5.9 1.4 0.9 1.9 3.1 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 6.5 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.1 17.4 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.0 1.7 1.9 1.8 2.1 2.3 2.2 2.9 2.1 2.1 1.9 2.5 6.4 45.9 24.5 0.6 0.9 0.9 9.3 1.8 0.0 5.4 4.3 0.5 31.5 23.9 3.7 0.0 1.7 0.3 3.2 1.9 0.3 14.5 0.0 0.4 1.9 0.0 8.0 0.1 2.0 2.2 5.2 0.5 0.0 0.0 0.4 10.0 509.6 0.2 0.0 0.2 1.8 12.2 8.1 0.3 4.8 8.1 0.2 14.2 4.7 0.0 3.2 0.0 17.6 0.1 1.2 1.2 3.0 0.0 2.1 6.0 6.7 6.5 0.1 0.0 0.8 2.1 21.4 16.9 0.3 1.3 1.4 0.8 6.6 2.3 0.4 POSTN "OSF-2, periostin, PN" ENSG00000133110 Periostin Q15063 13 37562583-37598844 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 207.2;stomach 1: 174.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 295.7;Breast myoepithelial cells: 158.1;Endothelial cells: 134.6;Fibroblasts: 191.5;Smooth muscle cells: 151.5" "Cancer enhanced" "Detected in all" "breast cancer: 231.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "hTEC/SVTERT24-B: 490.2;SuSa: 440.5;U-138 MG: 619.3;U-2197: 427.2" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 6 "spinal cord: 87.9" HPA012306 Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to extracellular matrix" NA NA 660000000 "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" Nucleoplasm "HPA012306: AB_1854827" "unprognostic (7.73e-2)" "unprognostic (1.44e-3)" "unprognostic (2.19e-2)" "unprognostic (2.57e-2)" "unprognostic (4.73e-2)" "unprognostic (2.22e-2)" "unprognostic (4.19e-3)" "prognostic unfavorable (2.93e-4)" "unprognostic (3.05e-3)" "unprognostic (7.10e-2)" "unprognostic (1.32e-2)" "unprognostic (5.93e-2)" "prognostic unfavorable (1.83e-7)" "prognostic unfavorable (4.86e-4)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" "unprognostic (8.32e-3)" 71.4 5.2 4.5 23.8 0.1 0.3 84.0 0.0 4.4 20.3 2.9 61.3 5.1 53.2 13.0 20.5 83.5 64.3 83.2 3.0 0.0 28.1 13.0 45.1 12.8 0.9 0.0 3.6 2.2 21.6 2.4 60.9 2.0 16.1 84.9 0.0 17.7 44.8 10.6 207.2 15.0 66.6 0.0 1.1 174.6 3.4 0.1 5.8 19.1 29.9 3.9 91.4 10.7 0.4 0.0 0.0 71.0 1.6 85.0 51.0 0.2 23.1 0.0 5.5 0.7 0.0 1.4 0.1 0.0 18.7 0.1 0.0 0.7 0.0 2.6 0.0 0.0 0.0 0.0 0.0 14.2 0.2 0.1 90.8 0.0 490.2 1.9 15.9 0.7 0.0 0.0 0.0 11.8 0.0 0.3 0.4 4.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.4 0.2 0.1 0.6 0.0 440.5 0.9 0.0 0.0 619.3 0.3 427.2 3.4 0.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.0 4.4 3.0 0.0 0.9 0.0 2.0 0.0 0.1 0.4 46.7 6.4 10.6 0.7 0.3 295.7 1.3 51.5 0.0 0.0 2.9 158.1 22.8 0.0 18.7 0.0 0.0 2.5 1.0 0.0 0.0 0.0 0.5 0.5 9.8 134.6 0.0 0.0 1.5 0.0 0.2 191.5 0.0 0.3 3.8 0.0 22.5 0.6 3.7 0.0 36.8 0.0 24.4 0.0 27.0 1.1 6.5 0.8 30.2 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.7 0.4 0.4 0.0 0.0 5.6 0.0 0.0 0.7 151.5 1.3 0.9 0.2 48.4 3.4 2.3 49.3 0.0 0.3 PPA2 FLJ20459 ENSG00000138777 "Inorganic pyrophosphatase 2" Q9H2U2 4 105369077-105474067 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030888, HPA031671, HPA031672" Supported Approved Mitochondria NA NA 150000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA030888: AB_2673646, HPA031671: AB_10603986, HPA031672: AB_2673988" "prognostic unfavorable (2.98e-4)" "unprognostic (5.64e-2)" "prognostic favorable (6.60e-4)" "unprognostic (9.26e-3)" "unprognostic (2.93e-2)" "unprognostic (5.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.44e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "unprognostic (9.54e-2)" "prognostic favorable (1.27e-11)" "unprognostic (3.69e-1)" "unprognostic (1.94e-1)" "unprognostic (2.00e-1)" "unprognostic (1.10e-1)" 7.4 12.8 23.8 9.0 24.6 22.0 12.0 24.3 53.7 7.4 29.5 17.4 14.2 7.4 12.5 10.8 8.4 8.0 27.5 23.7 26.3 20.7 14.8 7.5 8.3 24.4 24.3 5.8 11.8 11.7 7.7 7.4 24.5 13.3 14.0 13.6 13.8 5.7 27.6 12.2 13.8 6.8 24.0 9.9 12.6 6.3 25.4 7.0 11.5 35.5 8.7 8.1 6.7 26.6 20.6 8.5 18.5 32.3 11.3 9.1 12.9 10.2 15.7 14.6 9.9 22.2 30.4 15.6 14.5 9.7 11.3 9.5 39.2 18.7 17.0 23.6 11.8 13.5 13.7 19.9 9.3 36.7 13.6 9.7 19.6 9.9 7.9 15.4 14.6 28.4 22.3 22.0 12.5 26.2 32.5 26.6 13.9 42.4 28.3 28.2 10.9 17.9 49.7 14.7 17.8 10.7 7.8 48.9 19.0 10.7 24.8 32.1 6.9 9.2 19.2 8.9 20.0 19.0 27.3 18.4 17.5 18.6 14.1 27.0 20.9 15.4 21.0 30.1 18.6 28.5 21.7 23.7 49.9 22.6 21.1 23.9 9.5 36.4 26.4 25.9 23.4 23.5 23.8 24.6 24.3 53.7 23.7 26.3 24.4 24.3 24.5 24.0 25.4 26.6 26.7 9.6 67.3 86.2 37.6 50.0 82.4 205.0 38.1 29.7 64.8 40.9 63.3 45.8 126.2 33.1 16.7 119.0 25.9 73.3 264.1 114.0 113.7 42.3 35.3 36.3 65.7 70.2 138.2 120.1 98.5 31.1 37.2 42.3 45.6 26.4 24.3 64.2 83.5 21.9 134.6 104.6 142.4 42.9 86.1 126.4 27.7 47.1 76.5 74.9 50.5 39.2 30.9 169.9 145.7 65.0 90.4 32.4 41.9 68.1 112.2 285.4 90.7 22.6 39.5 46.3 43.6 50.8 10.8 59.1 57.7 84.7 34.3 72.1 138.0 94.6 PPAN "BXDC3, SSF, SSF1, SSF2" ENSG00000130810 "Peter pan homolog" Q9NQ55 19 10106362-10112012 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 243.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043265 Approved NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA043265: AB_10793943" "unprognostic (1.91e-2)" "unprognostic (1.27e-1)" "unprognostic (7.97e-2)" "unprognostic (1.30e-1)" "unprognostic (4.93e-2)" "unprognostic (4.23e-2)" "unprognostic (9.47e-3)" "unprognostic (2.13e-1)" "unprognostic (3.80e-1)" "unprognostic (5.51e-2)" "unprognostic (3.10e-2)" "unprognostic (1.94e-2)" "unprognostic (2.01e-3)" "unprognostic (8.75e-3)" "unprognostic (7.52e-2)" "unprognostic (4.27e-2)" "unprognostic (2.92e-3)" 23.3 20.5 4.9 15.8 5.3 12.3 20.2 6.6 7.7 18.3 2.5 18.8 12.3 19.3 4.0 27.8 18.9 6.9 17.6 5.1 4.0 18.9 24.5 14.8 18.1 4.1 4.2 19.6 23.2 8.4 13.8 7.5 4.3 19.5 5.8 4.8 16.6 6.8 32.8 28.2 20.0 6.9 1.9 26.5 18.4 18.9 5.5 10.0 16.0 11.1 12.0 20.4 20.5 8.8 51.0 42.0 16.0 35.9 10.8 11.4 34.2 26.7 12.8 33.7 26.3 56.0 19.5 59.0 48.0 17.2 24.4 42.6 42.0 47.7 14.5 31.8 104.6 104.1 47.6 55.2 27.5 66.4 62.5 17.9 36.0 37.0 46.0 22.0 17.2 45.6 76.1 54.9 17.7 72.2 82.5 243.5 75.1 26.8 103.2 60.2 20.5 80.4 19.0 44.8 33.7 41.7 23.9 42.9 40.8 10.6 23.8 37.2 21.1 45.8 24.3 50.6 70.9 111.0 59.3 61.2 31.8 60.2 41.4 2.4 7.1 4.0 6.7 5.0 8.6 17.0 9.2 10.7 6.6 20.6 12.9 5.9 4.7 5.6 3.7 5.0 9.7 3.2 4.9 5.3 6.6 7.7 5.1 4.0 4.1 4.2 4.3 1.9 5.5 8.8 12.2 3.2 6.4 0.0 20.2 57.4 50.3 15.4 4.0 11.3 12.8 14.1 3.9 10.0 12.1 5.5 6.2 26.4 24.0 20.0 3.9 33.2 9.0 4.6 10.5 13.0 6.7 10.3 0.0 30.6 32.0 14.1 6.1 5.1 7.0 13.8 10.4 11.4 32.4 18.5 0.0 17.7 16.2 7.6 17.0 9.1 18.6 10.5 12.4 0.0 15.7 5.0 18.6 0.0 0.0 31.7 12.6 10.5 9.9 33.2 10.3 18.9 5.8 9.9 0.0 18.8 16.7 22.7 42.1 6.8 52.8 17.8 18.9 19.9 24.9 27.9 PPBP "b-TG1, Beta-TG, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, NAP-2-L1, PBP, SCYB7, TGB, TGB1, THBGB1" ENSG00000163736 "Pro-platelet basic protein" P02775 4 73986439-73988190 "Plasma proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 98.7;lymphoid tissue: 53.6" "Cell type enriched" "Detected in some" 18 "Macrophages: 1497.3" "Cancer enriched" "Detected in many" 7 "colorectal cancer: 86.8" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 13 "basophil: 394.2;neutrophil: 132.3" "Lineage enriched" "Detected in all" 20 "granulocytes: 394.2" "Cell line enhanced" "Detected in some" "HBEC3-KT: 1.0;HEL: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008354, CAB017624" Supported "Secreted to blood" NA NA 24500000 2900000000 "Cluster 34: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "CAB017624: AB_1127132, HPA008354: AB_1847353" "unprognostic (2.13e-1)" "prognostic unfavorable (6.17e-4)" "unprognostic (7.69e-2)" "unprognostic (1.67e-1)" "unprognostic (4.37e-2)" "unprognostic (3.13e-1)" "unprognostic (2.79e-1)" "unprognostic (6.98e-3)" "unprognostic (2.58e-1)" "unprognostic (4.21e-2)" "unprognostic (1.81e-1)" "unprognostic (2.88e-1)" "unprognostic (2.38e-3)" "unprognostic (1.49e-1)" "unprognostic (2.90e-1)" "unprognostic (2.15e-3)" "unprognostic (2.59e-2)" 1.3 0.5 0.3 0.5 0.4 98.7 0.6 0.3 2.2 0.1 1.0 0.1 0.0 0.1 0.0 0.2 0.8 0.8 1.3 0.2 0.3 0.9 2.9 19.4 0.0 0.5 0.4 0.1 0.1 0.0 0.4 5.2 0.8 0.1 0.0 0.0 0.6 0.0 1.4 0.1 0.0 0.1 0.8 53.6 0.2 0.0 0.7 0.1 1.0 4.2 0.0 8.4 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 394.2 13.0 9.3 2.0 5.3 2.9 1.5 1.2 0.6 8.0 2.3 4.1 1.0 132.3 1.9 5.0 20.1 2.1 1791.5 0.3 0.4 0.3 2.2 0.2 0.3 0.5 0.4 0.8 0.8 0.7 0.4 0.3 3.2 1.1 0.0 10.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.5 4.0 1.8 0.0 0.0 9.3 0.1 0.0 4.7 0.0 0.0 0.0 12.3 0.0 2.7 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 36.8 1.1 0.1 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 1497.3 0.0 0.0 80.8 0.0 75.2 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.0 0.3 1.7 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.1 7.8 0.0 0.0 0.0 PPCDC "FLJ14585, MDS018" ENSG00000138621 "Phosphopantothenoylcysteine decarboxylase" Q96CD2 15 75023586-75117462 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 71.4;granulocytes: 153.5;monocytes: 71.6" "Cell line enhanced" "Detected in all" "Karpas-707: 133.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045667 Approved Approved Cytosol NA NA 25000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA045667: AB_2679412" "unprognostic (8.66e-2)" "unprognostic (1.07e-3)" "unprognostic (6.03e-2)" "unprognostic (2.57e-2)" "unprognostic (2.95e-2)" "unprognostic (6.53e-2)" "unprognostic (1.76e-2)" "unprognostic (8.40e-2)" "unprognostic (1.72e-1)" "unprognostic (1.53e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (1.60e-2)" "unprognostic (7.67e-2)" "unprognostic (1.73e-1)" "unprognostic (3.43e-1)" "unprognostic (2.13e-3)" 11.1 19.1 7.4 10.8 8.8 19.7 10.9 8.3 8.4 9.7 8.7 11.5 9.7 8.3 9.8 19.0 10.8 8.4 8.5 6.9 8.0 17.2 13.1 10.8 16.4 9.2 8.8 9.0 16.5 21.3 9.3 9.2 8.5 13.0 9.4 7.6 13.9 7.6 11.9 9.0 9.9 5.4 8.0 18.8 11.3 9.7 8.6 12.1 11.2 5.9 12.3 11.2 10.0 10.3 15.6 28.8 11.8 9.2 7.0 6.4 10.1 15.5 7.0 20.3 15.9 16.9 41.2 17.7 26.8 7.8 12.5 15.9 19.2 25.6 10.4 62.6 23.4 31.1 18.8 18.3 19.9 18.3 38.7 8.6 16.7 21.0 32.3 8.2 16.6 25.8 21.3 133.2 14.8 30.0 10.9 28.1 18.9 32.9 13.4 18.2 23.0 38.3 15.3 22.2 28.3 8.3 22.9 31.3 34.6 13.4 38.7 23.4 9.4 20.6 14.4 10.5 27.6 40.5 29.3 30.1 12.7 45.9 23.7 47.2 23.1 153.5 11.6 65.6 19.4 15.7 10.6 13.0 17.6 8.6 11.7 14.5 139.7 18.5 71.6 71.4 12.7 15.8 7.4 8.8 8.3 8.4 6.9 8.0 9.2 8.8 8.5 8.0 8.6 10.3 10.2 16.0 5.2 2.9 10.5 3.8 6.1 8.5 8.6 2.8 9.6 8.8 4.2 4.3 9.7 9.2 0.0 17.5 16.0 19.7 25.4 17.3 1.0 8.2 4.3 10.7 4.2 11.6 1.4 15.3 13.6 7.4 14.8 8.3 12.0 9.9 10.4 5.3 20.0 8.4 1.7 10.9 12.2 15.7 6.7 2.5 4.4 15.5 14.2 2.8 20.0 4.7 8.2 2.5 4.6 18.0 38.1 5.3 33.9 6.5 10.5 19.0 12.2 10.7 6.6 6.3 8.7 6.9 15.7 10.8 4.0 10.9 9.7 11.3 11.7 13.6 PPIB "B, CYP-S1, CYPB, OI9, PPIase, SCYLP" ENSG00000166794 "Peptidylprolyl isomerase B" P23284 15 64155740-64163134 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Isomerase, Rotamase" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1473.7;Plasma cells: 2242.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011487, HPA012720" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" "Secreted to blood" No No 33000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" Nucleoplasm "CAB011487: AB_443295, HPA012720: AB_1847399" "unprognostic (3.00e-3)" "unprognostic (5.65e-3)" "unprognostic (2.81e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.65e-1)" "unprognostic (1.07e-3)" "unprognostic (3.69e-2)" "unprognostic (1.27e-2)" "unprognostic (7.19e-2)" "unprognostic (8.80e-3)" "unprognostic (2.87e-1)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.02e-11)" "unprognostic (7.05e-2)" "unprognostic (3.77e-2)" "unprognostic (1.82e-1)" "unprognostic (3.90e-2)" 375.5 377.5 230.7 449.5 240.3 571.9 361.9 247.9 259.2 611.5 257.2 401.0 365.0 383.9 899.0 298.8 401.5 379.2 262.0 229.7 256.9 312.3 737.4 351.1 344.5 258.1 241.4 386.2 644.2 345.4 416.8 515.2 255.1 375.7 411.3 72.3 513.1 488.6 62.2 205.5 334.3 482.4 247.0 360.5 375.0 110.0 254.9 315.6 672.8 91.1 346.4 510.9 295.6 262.6 675.6 847.9 736.7 1666.7 2577.0 1492.3 641.9 1570.3 2108.3 1248.7 1472.3 1242.6 1223.1 653.6 1227.4 2513.0 1235.3 1067.7 1384.6 1080.4 641.1 406.2 491.0 914.5 915.3 1643.7 2682.9 915.0 778.1 1374.2 1149.4 725.9 1751.3 1516.7 1539.2 301.1 645.9 2174.7 966.0 1102.6 280.6 1404.9 625.1 1879.0 529.5 520.6 784.1 3347.9 1312.7 1062.6 410.5 647.7 726.0 1224.5 1194.2 1086.0 727.6 2767.0 927.6 1213.7 975.8 679.2 1079.4 1152.5 1269.5 693.4 1129.0 1478.0 1238.2 716.7 712.5 491.7 929.6 547.3 931.8 827.8 645.0 762.4 930.9 541.4 411.3 558.0 347.5 668.1 369.3 2643.5 569.3 1512.3 230.7 240.3 247.9 259.2 229.7 256.9 258.1 241.4 255.1 247.0 254.9 262.6 389.3 125.0 209.0 16.6 375.3 160.2 426.2 614.6 234.5 34.5 264.3 303.8 0.8 270.2 328.7 272.2 31.3 625.9 560.0 271.0 90.1 665.1 19.0 295.8 910.1 285.0 297.0 172.6 10.2 566.4 1473.7 627.8 441.4 494.2 181.2 540.4 322.7 473.2 630.1 45.4 15.8 603.9 205.4 216.9 333.4 29.5 456.3 316.6 281.1 19.7 299.1 149.1 368.7 35.2 37.0 435.1 338.9 393.1 2242.6 569.3 338.6 287.4 168.2 43.7 230.1 204.3 445.6 38.4 76.6 337.0 144.8 1118.9 352.3 674.0 477.2 422.3 PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036725 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 251.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 229.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" NA NA 3700000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA039163: AB_2676374" "unprognostic (7.81e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.49e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (3.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" "unprognostic (4.27e-2)" "unprognostic (2.43e-2)" 37.0 20.6 5.3 16.4 5.6 0.2 30.4 6.8 7.0 42.3 12.2 41.4 37.3 31.0 36.5 46.8 14.8 33.5 44.4 5.2 5.8 24.9 28.9 27.0 7.6 6.4 6.3 16.2 30.3 20.9 6.2 48.3 6.2 23.4 49.9 4.9 31.7 24.0 41.2 20.2 32.3 45.2 6.1 7.7 22.4 9.0 6.7 5.8 47.2 33.3 14.2 45.8 28.8 5.8 19.6 16.8 6.4 136.2 229.7 104.6 26.9 54.4 42.3 27.8 56.7 28.1 128.6 0.0 94.2 147.1 83.3 21.9 18.9 68.6 22.1 0.1 33.1 27.8 60.7 32.8 58.9 0.0 14.7 65.8 51.5 32.5 34.0 49.9 58.1 0.0 7.9 0.0 20.1 116.5 0.1 0.3 11.6 120.9 29.0 0.0 14.5 0.0 87.7 67.0 8.5 14.9 106.7 51.1 12.1 77.8 72.0 61.8 64.8 52.9 32.7 18.5 23.9 0.2 0.1 0.4 45.9 0.2 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.6 6.8 7.0 5.2 5.8 6.4 6.3 6.2 6.1 6.7 5.8 214.1 32.1 16.5 6.2 1.6 47.4 52.3 251.7 30.7 16.9 63.9 47.5 46.4 61.5 149.0 73.5 4.2 60.1 0.6 134.0 29.4 201.5 1.7 52.4 94.8 106.5 12.7 0.0 0.8 126.4 65.2 198.2 55.0 50.8 1.3 54.2 80.7 57.8 43.2 0.0 2.2 177.1 207.5 4.2 40.3 4.2 112.5 6.9 32.0 5.6 3.2 2.8 0.0 1.0 0.3 90.3 181.0 100.1 0.6 48.2 189.0 81.7 110.5 4.4 39.5 22.7 87.5 41.6 37.8 118.6 49.3 25.0 3.4 61.2 117.0 81.5 PPIF "Cyp-D, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355334 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Necrosis" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 370.9;Macrophages: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 75.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria NA NA 320000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA077416: AB_2686840" "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" 62.7 227.7 42.7 42.8 48.4 168.8 42.4 57.9 69.6 27.6 63.7 50.0 36.3 14.0 7.2 66.0 22.9 19.5 119.1 38.1 45.2 63.3 174.9 29.1 32.3 49.0 56.2 19.3 86.9 77.6 18.3 27.1 48.8 18.8 52.4 8.9 39.5 45.5 99.5 71.9 31.3 21.0 50.6 58.7 98.2 35.0 57.1 28.3 26.0 133.6 55.5 60.0 35.1 60.8 220.4 90.6 62.3 123.5 57.0 73.6 79.8 124.2 161.2 265.7 249.6 213.5 102.7 224.8 68.0 87.4 188.6 127.8 195.3 115.4 410.5 72.2 186.4 352.8 87.5 380.7 96.4 245.7 80.4 173.2 81.3 264.5 262.3 86.5 47.5 86.4 351.6 268.3 91.6 111.7 64.1 204.2 53.0 99.6 500.6 109.8 96.4 114.7 103.9 200.0 124.1 92.0 63.6 253.8 97.9 40.5 111.4 187.2 43.5 116.1 106.3 137.9 242.0 124.7 137.7 181.9 114.5 313.9 32.0 15.2 34.3 18.0 10.4 27.5 10.9 19.1 9.1 9.6 43.3 7.7 8.1 7.9 75.0 9.0 10.4 5.4 10.0 16.6 42.7 48.4 57.9 69.6 38.1 45.2 49.0 56.2 48.8 50.6 57.1 60.8 8.4 6.4 6.8 7.2 32.7 42.6 30.2 23.8 31.3 4.0 41.8 40.8 124.6 14.3 14.4 12.9 6.2 99.4 26.4 39.9 92.0 42.1 14.5 12.4 24.0 10.1 21.6 37.0 4.1 28.0 127.1 25.1 78.0 15.5 13.4 73.4 6.1 98.5 91.1 8.4 5.7 69.5 18.3 40.3 370.9 14.1 6.2 160.8 35.6 4.7 32.0 13.0 5.2 5.5 15.0 39.8 26.6 6.0 48.7 41.4 21.3 41.2 12.6 5.2 19.7 18.2 28.6 14.8 22.5 52.9 37.6 142.3 23.9 60.2 81.1 34.2 PPIL6 "bA425D10.6, dJ919F19.1, MGC41939, RSPH12" ENSG00000185250 "Peptidylprolyl isomerase like 6" Q8IXY8 6 109390215-109441171 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 35.6;testis: 18.9" "Cell type enhanced" "Detected in many" "Early spermatids: 374.4;Endometrial ciliated cells: 226.5;Late spermatids: 75.1;Respiratory ciliated cells: 228.6;Spermatocytes: 101.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AN3-CA: 6.0;ASC diff: 9.2;ASC TERT1: 11.5;hTERT-RPE1: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036717, HPA058165" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA036717: AB_10671969, HPA058165: " "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (5.68e-2)" "unprognostic (2.68e-2)" "unprognostic (3.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-1)" "unprognostic (5.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.03e-2)" "unprognostic (1.42e-3)" "unprognostic (2.51e-2)" "unprognostic (4.71e-2)" "unprognostic (1.95e-1)" "unprognostic (3.29e-2)" "unprognostic (5.86e-2)" "unprognostic (2.32e-1)" 1.1 0.9 4.7 0.6 5.2 0.2 3.0 5.7 5.3 3.8 12.2 1.3 1.4 3.0 9.0 1.4 35.6 1.1 2.1 4.8 5.2 4.3 0.6 4.7 0.6 7.5 8.2 5.3 2.3 5.2 2.7 1.1 5.5 1.2 1.0 7.4 2.3 2.7 4.3 1.3 0.7 2.0 7.2 0.8 1.7 18.9 5.1 0.8 11.1 1.7 0.6 1.5 1.2 7.6 1.4 1.2 1.1 6.0 9.2 11.5 0.6 0.0 2.2 0.5 0.1 0.1 1.6 0.0 0.4 0.6 0.8 0.9 1.0 0.0 0.3 0.4 0.4 0.5 0.1 0.0 4.6 0.5 0.2 2.4 5.6 0.2 3.5 8.6 0.7 1.3 0.6 0.4 0.4 0.6 0.1 0.7 0.2 4.0 0.8 0.6 0.0 0.5 4.7 0.1 1.3 2.1 0.1 0.3 3.9 0.3 0.4 0.9 0.3 0.1 0.2 1.0 0.2 0.2 0.1 0.1 1.9 0.1 0.4 0.8 0.1 0.2 0.1 0.1 0.1 1.5 0.2 0.1 0.3 0.5 0.1 0.1 0.4 0.4 0.1 0.4 0.1 0.2 4.7 5.2 5.7 5.3 4.8 5.2 7.5 8.2 5.5 7.2 5.1 7.6 2.6 6.4 6.9 11.8 1.8 2.2 3.7 18.2 2.8 2.4 5.7 7.0 3.7 2.8 22.1 3.7 2.1 0.8 0.4 0.9 25.4 1.9 374.4 226.5 7.3 1.8 3.0 0.4 15.0 1.2 0.8 3.9 2.6 5.8 0.0 4.1 1.1 0.2 0.4 1.7 6.1 2.0 22.4 0.0 0.3 75.1 5.3 1.1 3.6 3.7 0.6 7.8 0.0 8.5 6.2 0.7 0.8 5.3 0.8 3.8 1.5 13.0 228.6 13.4 0.0 5.2 5.6 101.4 21.5 1.9 3.0 0.7 1.2 3.0 2.0 1.5 PPM1H "ARHCL1, FLJ13253, KIAA1157, NERPP-2C" ENSG00000111110 "Protein phosphatase, Mg2+/Mn2+ dependent 1H" Q9ULR3 12 62643994-62935150 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.0;parathyroid gland: 42.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 123.5;Glandular and luminal cells: 81.6;Inhibitory neurons: 162.1;Microglial cells: 89.9;Oligodendrocytes: 341.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 80.6;HMC-1: 62.7;SK-BR-3: 35.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020694, HPA044244, HPA058777" Approved Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB020694: , HPA044244: AB_2678871, HPA058777: AB_2683816" "unprognostic (3.41e-2)" "unprognostic (1.94e-1)" "unprognostic (9.51e-2)" "unprognostic (8.61e-3)" "unprognostic (1.44e-1)" "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (5.85e-2)" "unprognostic (3.17e-1)" "unprognostic (1.78e-2)" "unprognostic (5.53e-3)" "unprognostic (2.19e-1)" "prognostic favorable (2.72e-5)" "unprognostic (3.90e-2)" "unprognostic (1.73e-1)" "unprognostic (8.04e-3)" "unprognostic (1.14e-1)" 2.2 1.5 12.0 1.2 12.7 3.1 4.9 30.0 16.0 7.5 5.7 2.4 3.1 6.2 6.7 0.6 6.5 6.7 2.4 13.3 15.7 10.6 3.4 2.7 1.2 11.1 11.3 9.6 3.9 42.4 8.2 6.5 14.9 13.4 3.0 26.7 11.4 6.0 1.1 0.8 1.7 1.5 7.8 0.9 5.7 0.9 16.5 4.3 3.2 1.3 1.7 2.1 0.3 16.2 1.2 12.4 2.2 0.2 0.5 0.0 26.5 2.9 2.9 1.8 0.6 80.6 5.7 0.0 2.7 1.4 1.8 1.6 8.7 0.2 1.1 0.2 4.3 15.2 2.4 18.4 0.1 4.6 62.7 0.1 0.3 0.0 0.7 1.9 0.3 2.7 4.0 0.0 1.3 9.5 1.5 2.2 15.9 4.1 5.9 2.1 5.6 23.0 18.1 28.3 6.9 0.0 5.0 35.6 12.1 8.5 19.6 2.7 0.2 0.5 1.5 0.2 0.9 3.3 21.4 4.1 0.2 0.1 1.2 2.9 0.7 1.4 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.1 0.6 0.0 0.0 0.1 12.0 12.7 30.0 16.0 13.3 15.7 11.1 11.3 14.9 7.8 16.5 16.2 4.6 6.4 4.7 25.5 1.0 0.1 0.3 3.0 0.0 9.4 9.5 3.4 2.4 12.8 5.9 16.5 27.1 22.2 0.0 0.7 3.9 4.2 8.5 27.6 25.3 6.5 9.0 3.8 123.5 6.3 2.1 1.3 7.7 81.6 14.5 0.3 9.7 6.1 6.1 11.8 162.1 2.0 6.1 1.6 2.1 10.1 0.9 2.1 3.6 89.9 2.1 6.4 0.0 41.7 341.4 4.5 2.1 1.5 0.5 4.3 0.1 8.5 14.0 10.9 0.0 0.6 1.7 0.0 0.5 0.5 0.1 6.8 1.3 2.8 2.4 0.5 PPM1M "FLJ32332, PP2Ceta" ENSG00000164088 "Protein phosphatase, Mg2+/Mn2+ dependent 1M" Q96MI6 3 52245759-52250599 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 42.2;Kupffer cells: 39.0;Macrophages: 31.1;NK-cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 54.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036905, HPA062291" Uncertain Approved "Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear bodies" "HPA036905: AB_10602818, HPA062291: AB_2684740" "unprognostic (4.26e-3)" "prognostic favorable (7.73e-4)" "unprognostic (2.55e-2)" "unprognostic (4.85e-3)" "unprognostic (5.64e-2)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "prognostic favorable (6.69e-4)" "unprognostic (4.63e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.49e-1)" "unprognostic (4.14e-2)" "unprognostic (9.27e-2)" "unprognostic (4.37e-2)" 19.5 9.4 12.7 20.3 13.7 24.6 15.5 9.9 13.6 25.9 12.2 18.7 6.0 18.3 9.9 12.3 18.1 14.1 11.4 13.6 14.2 10.9 5.6 23.5 29.6 12.8 11.4 18.6 8.0 11.2 9.1 11.6 12.2 16.7 8.7 2.2 11.6 15.2 3.7 10.7 13.1 18.0 12.0 30.1 11.4 8.8 15.5 27.6 13.8 7.8 28.2 17.5 18.2 12.9 0.9 5.4 3.2 7.6 46.1 45.7 5.2 12.2 26.2 17.0 13.1 3.2 4.2 9.0 3.6 32.0 9.5 1.5 10.9 2.3 6.9 11.0 2.7 20.5 14.6 3.3 33.6 3.1 18.7 37.8 5.2 18.9 11.9 27.3 22.2 40.5 3.6 14.5 20.2 2.2 13.7 0.9 4.1 4.0 14.7 3.0 1.6 20.0 7.3 2.6 2.3 9.3 9.0 2.2 11.1 6.8 7.6 7.9 15.5 6.5 10.7 3.8 1.6 54.3 11.2 9.9 12.7 5.4 8.0 1.8 24.1 13.3 20.6 19.3 15.9 6.8 16.1 19.2 14.4 7.4 15.2 19.0 28.9 11.7 29.6 8.5 20.5 17.5 12.7 13.7 9.9 13.6 13.6 14.2 12.8 11.4 12.2 12.0 15.5 12.9 6.8 0.0 5.4 1.3 15.4 5.1 6.5 0.7 8.0 1.6 5.9 7.2 1.8 5.7 2.0 1.8 0.0 3.3 25.9 0.7 3.9 1.8 9.7 4.7 8.9 7.0 1.2 3.0 1.5 1.1 5.8 11.9 3.1 11.0 5.7 7.3 12.5 3.7 42.2 1.7 0.6 0.4 2.0 39.0 17.0 18.0 12.8 31.1 5.4 4.7 29.1 5.1 30.9 1.5 0.7 1.3 3.2 9.8 11.4 2.3 0.9 3.0 0.9 0.7 19.7 5.2 7.3 0.7 4.2 11.9 3.8 1.9 25.1 3.1 1.0 3.5 PPOX "PPO, VP" ENSG00000143224 "Protoporphyrinogen oxidase" P50336 1 161166056-161178013 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 65.9;Respiratory ciliated cells: 84.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030123 Uncertain Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Vesicles, Cytosol" "HPA030123: AB_10603987" "unprognostic (1.17e-1)" "unprognostic (4.73e-2)" "unprognostic (9.88e-2)" "unprognostic (2.13e-2)" "unprognostic (3.24e-1)" "unprognostic (1.64e-2)" "unprognostic (9.58e-3)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.18e-3)" "unprognostic (7.12e-3)" "prognostic unfavorable (9.89e-4)" "unprognostic (6.12e-2)" "unprognostic (2.23e-1)" "unprognostic (3.27e-1)" "unprognostic (1.80e-2)" 9.3 17.1 24.2 3.5 24.5 25.2 10.3 25.2 38.2 14.5 24.7 12.7 3.9 10.9 8.3 8.9 22.0 4.7 13.1 24.4 24.7 15.5 11.5 8.6 5.7 25.0 25.0 13.8 10.8 7.2 13.7 6.5 24.6 13.4 3.9 12.6 8.7 7.7 7.6 11.2 8.5 6.6 25.0 13.6 10.9 6.9 24.0 5.0 11.9 5.6 5.2 11.6 9.6 25.4 10.0 8.0 12.7 8.5 10.4 9.3 3.5 5.9 5.7 7.5 10.3 10.4 9.3 7.4 14.3 5.3 4.1 6.3 9.8 8.8 7.1 4.6 20.3 9.0 18.9 23.9 8.6 3.0 4.6 7.6 11.0 6.3 9.4 9.4 14.7 7.0 22.8 11.2 5.6 9.2 12.0 8.6 8.2 11.2 18.8 13.6 8.2 16.7 15.1 4.2 9.8 14.7 6.6 10.3 12.0 14.6 19.9 9.5 5.7 6.5 7.1 6.5 7.5 19.4 15.3 10.5 6.8 6.0 4.9 6.3 7.2 5.3 10.4 7.6 7.2 9.0 7.8 7.6 10.4 8.2 6.8 6.9 2.9 12.0 5.2 6.6 16.1 7.8 24.2 24.5 25.2 38.2 24.4 24.7 25.0 25.0 24.6 25.0 24.0 25.4 10.9 3.2 13.7 10.4 9.8 12.0 8.3 16.6 9.1 18.0 12.1 14.1 10.1 4.3 15.6 7.3 22.9 21.4 10.6 3.6 21.5 9.5 9.8 39.1 5.9 8.3 6.0 65.9 5.9 5.6 9.4 9.1 5.1 4.6 6.3 12.3 8.9 6.1 9.3 15.2 7.5 7.3 26.4 4.7 8.4 12.1 10.2 8.0 1.8 5.6 8.1 10.4 8.2 9.0 8.9 6.3 3.8 6.8 16.9 3.2 6.6 17.2 84.4 20.9 6.6 9.6 15.6 12.8 9.3 7.2 14.9 10.4 10.6 11.1 7.5 6.2 PPP1R15A GADD34 ENSG00000087074 "Protein phosphatase 1 regulatory subunit 15A" O75807 19 48872421-48876058 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Stress response, Translation regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 575.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 340.1" "Group enriched" "Detected in all" 5 "dendritic cells: 114.6;granulocytes: 340.1" "Cell line enhanced" "Detected in all" "HHSteC: 282.8;hTERT-HME1: 493.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018395, HPA020240" Approved Uncertain Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Vesicles "CAB018395: AB_2237473, HPA020240: AB_1849404" "unprognostic (2.43e-3)" "unprognostic (3.21e-1)" "unprognostic (7.75e-2)" "unprognostic (1.17e-3)" "unprognostic (2.22e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (5.46e-2)" "unprognostic (2.66e-2)" "unprognostic (7.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.22e-1)" "unprognostic (6.43e-3)" "unprognostic (1.49e-1)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" 199.1 84.7 33.3 49.5 37.4 575.6 97.7 45.9 54.1 99.5 66.9 78.9 36.0 70.1 11.3 98.3 147.4 82.0 185.6 34.8 36.2 95.0 85.1 226.7 33.1 44.8 32.7 101.2 33.4 23.1 65.0 74.8 42.9 60.5 45.5 10.9 41.6 38.6 88.5 191.5 58.8 101.8 29.4 69.0 90.7 23.3 38.7 52.0 69.4 60.6 20.2 110.6 108.4 46.9 55.8 23.7 24.9 20.5 71.2 40.4 39.3 95.1 148.0 106.5 95.9 36.5 27.6 19.1 25.0 69.0 145.5 39.4 9.3 49.7 79.8 10.7 14.4 86.4 14.4 18.1 282.8 20.2 119.2 55.1 135.5 147.0 493.7 48.0 56.3 21.5 118.2 155.6 69.5 6.1 11.1 27.9 6.2 100.3 42.3 12.6 23.1 6.5 22.3 63.8 14.2 24.3 49.2 33.2 230.2 26.0 11.9 36.1 60.6 126.3 31.8 89.3 58.5 82.8 72.1 17.9 46.2 13.7 154.8 161.8 49.4 91.3 22.5 31.1 19.6 36.7 22.2 18.7 35.9 29.7 12.3 11.0 340.1 13.8 37.6 114.6 31.5 36.9 33.3 37.4 45.9 54.1 34.8 36.2 44.8 32.7 42.9 29.4 38.7 46.9 499.1 288.4 225.1 2.3 387.2 482.2 989.5 232.0 730.1 25.0 294.3 220.7 173.3 127.2 204.3 12.9 35.5 104.8 290.3 435.6 3.9 224.0 4.6 619.6 427.4 370.4 170.9 213.5 4.1 94.5 219.0 466.3 430.7 1063.2 708.1 53.3 150.0 14.4 195.0 35.3 4.1 354.1 140.4 146.7 904.4 5.1 58.7 615.3 396.6 9.4 105.1 50.5 20.6 1.0 2.0 233.4 421.8 23.0 477.1 731.5 348.7 9.0 246.2 27.7 85.5 483.5 612.1 7.0 9.5 573.1 431.0 288.4 427.9 102.8 321.8 733.9 PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52190048-52229518 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromosome partition" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB018599: AB_628178" "unprognostic (1.78e-1)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (2.87e-1)" "unprognostic (6.67e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.76e-4)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.48e-3)" "unprognostic (8.28e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.97e-1)" "unprognostic (3.57e-2)" "unprognostic (1.70e-2)" "unprognostic (9.19e-2)" 98.5 300.7 305.0 60.5 311.1 58.1 98.7 292.0 394.2 126.9 261.4 115.7 91.5 126.8 101.0 164.4 126.8 63.2 322.8 342.6 299.4 156.9 106.0 87.5 72.7 308.9 301.1 163.7 100.7 129.9 123.9 69.1 312.8 123.3 82.2 89.8 99.8 92.2 239.7 119.3 98.5 96.0 280.1 87.6 106.0 67.2 331.7 76.9 107.9 170.7 90.0 123.5 121.9 299.2 153.6 248.4 210.9 182.0 166.9 173.4 105.3 130.3 173.2 174.1 151.1 129.3 122.1 132.5 91.0 213.9 95.7 108.8 228.0 197.9 100.6 101.3 562.8 99.6 126.9 148.2 152.6 105.6 93.1 234.3 163.8 163.5 149.2 162.9 167.9 92.1 114.3 96.8 196.3 178.6 159.6 215.4 204.6 162.2 218.4 148.6 118.3 152.5 285.0 251.7 153.3 161.3 149.0 160.1 100.3 136.3 141.9 197.3 153.1 133.2 120.5 65.7 154.2 96.9 151.5 160.0 143.1 109.7 170.5 172.6 172.0 169.4 143.9 212.2 131.0 143.1 126.3 134.3 192.8 157.1 101.6 119.6 103.7 228.6 199.0 119.7 177.5 255.6 305.0 311.1 292.0 394.2 342.6 299.4 308.9 301.1 312.8 280.1 331.7 299.2 55.3 44.8 35.4 21.5 76.0 70.4 99.0 178.0 56.9 114.0 64.5 71.1 100.2 74.4 99.5 119.5 25.0 203.7 47.3 157.0 117.4 213.5 4.4 77.5 79.7 72.4 107.0 39.7 27.4 155.7 259.9 85.7 77.5 100.7 68.5 96.7 65.0 52.8 146.2 144.7 39.5 128.8 144.5 68.1 39.3 10.4 72.4 58.0 53.4 17.8 103.7 118.0 62.8 25.6 29.9 168.2 189.0 85.4 60.3 88.3 147.5 135.3 80.6 61.5 78.9 49.2 90.3 16.5 68.8 74.4 63.2 182.0 64.2 99.7 185.2 104.2 PPP6R2 "dJ579N16.1, KIAA0685, SAP190, SAPS2" ENSG00000100239 "Protein phosphatase 6 regulatory subunit 2" O75170 22 50343304-50445090 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030656, CAB034919" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Vesicles, Cytosol" "CAB034919: AB_2183817, HPA030656: AB_10602926" "unprognostic (1.24e-1)" "unprognostic (1.82e-3)" "unprognostic (1.03e-1)" "prognostic favorable (1.70e-5)" "unprognostic (2.17e-1)" "unprognostic (3.79e-3)" "unprognostic (2.32e-1)" "unprognostic (1.30e-2)" "unprognostic (2.82e-1)" "unprognostic (1.82e-2)" "prognostic favorable (7.51e-4)" "unprognostic (6.89e-2)" "unprognostic (1.42e-2)" "unprognostic (1.20e-2)" "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (7.77e-3)" 21.9 35.6 23.5 20.9 27.3 21.4 23.2 24.3 32.2 23.7 19.2 28.5 24.5 25.4 11.5 28.3 23.8 18.0 36.7 25.4 19.7 29.6 72.4 25.2 27.3 26.9 22.2 24.8 29.0 21.4 41.0 14.8 21.8 31.4 11.8 12.6 27.9 17.1 65.8 27.6 28.7 14.0 18.2 32.4 30.1 62.7 26.0 25.8 30.8 31.7 16.5 23.9 22.3 25.8 30.9 17.8 27.3 34.8 19.7 21.0 24.4 30.1 31.9 31.5 31.7 15.0 18.7 36.9 14.5 30.0 17.4 24.6 16.9 22.4 11.8 19.3 30.9 19.8 37.7 37.7 25.6 46.9 52.1 31.2 23.8 19.0 10.1 24.8 27.8 30.8 20.5 31.5 23.2 50.0 32.3 33.9 11.3 19.5 21.9 44.8 20.9 24.3 23.1 36.1 17.0 23.1 31.0 47.6 25.0 10.1 17.2 35.2 32.5 29.3 26.4 24.6 20.3 33.6 8.7 32.7 30.6 22.6 41.2 4.0 8.6 5.8 9.0 9.4 10.4 7.9 6.2 9.6 8.8 8.4 5.9 7.9 13.7 5.9 6.8 11.0 13.3 8.5 23.5 27.3 24.3 32.2 25.4 19.7 26.9 22.2 21.8 18.2 26.0 25.8 28.5 22.4 20.6 79.0 32.0 8.8 14.4 12.9 22.8 43.7 25.5 21.8 19.2 37.1 17.1 27.6 56.3 17.3 39.9 39.8 31.3 19.3 84.0 30.8 39.0 18.1 26.9 19.8 83.0 32.5 11.8 15.3 35.2 34.8 31.8 23.9 18.9 65.1 16.0 65.6 80.8 23.0 16.2 25.3 8.8 48.6 19.6 23.4 10.6 61.8 32.1 25.0 50.4 52.8 59.9 33.3 29.0 19.9 42.0 19.4 27.0 23.6 17.9 43.2 26.3 16.9 18.7 78.5 47.1 17.9 8.5 28.5 28.4 17.8 25.2 17.5 PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40072710-40097260 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 251.9;Kupffer cells: 315.8;Langerhans cells: 328.8;Macrophages: 271.3;monocytes: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 1254.3;eosinophil: 624.2;intermediate monocyte: 1006.3;myeloid DC: 1091.1;neutrophil: 683.9;non-classical monocyte: 815.7" "Group enriched" "Detected in all" 4 "dendritic cells: 1091.1;granulocytes: 683.9;monocytes: 1254.3" "Cell line enhanced" "Detected in all" "SK-BR-3: 1082.7;THP-1: 1449.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 240000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" 69.8 59.4 92.9 92.7 95.6 117.5 95.7 100.4 135.9 70.1 106.1 50.5 32.1 72.7 60.1 45.1 55.4 57.1 45.3 93.6 101.2 75.8 54.1 128.5 93.9 97.0 96.7 68.6 42.6 79.2 39.0 74.8 99.6 73.4 58.8 89.4 56.8 63.2 21.3 40.3 39.2 95.3 101.6 177.0 45.1 37.6 99.1 78.0 60.0 37.1 75.1 79.1 34.7 113.5 115.6 62.5 93.7 81.0 106.5 92.1 209.8 68.4 127.9 153.0 183.3 350.1 270.5 140.1 118.1 65.2 112.2 209.5 154.9 112.7 163.6 186.4 151.4 100.3 127.2 155.5 137.5 233.7 158.9 103.1 107.5 108.7 126.4 79.7 190.9 108.8 167.7 247.0 80.6 168.1 109.8 88.3 258.3 163.9 93.8 116.0 263.7 226.1 89.2 152.0 114.1 96.9 247.9 1082.7 298.6 111.7 199.3 1449.6 85.2 100.7 147.1 70.7 174.9 161.2 383.8 133.9 109.4 408.7 155.5 85.7 1254.3 624.2 122.2 1006.3 137.9 118.8 171.5 131.3 1091.1 118.6 227.0 168.3 683.9 100.3 815.7 101.8 204.1 1586.9 92.9 95.6 100.4 135.9 93.6 101.2 97.0 96.7 99.6 101.6 99.1 113.5 45.2 28.9 47.7 19.9 33.3 39.6 77.1 30.8 34.7 46.6 55.3 37.5 15.7 41.5 40.0 38.6 16.7 51.7 28.9 4.7 5.9 59.0 64.8 13.8 46.4 49.6 19.9 40.1 28.4 42.1 66.5 56.6 14.8 18.2 84.9 34.6 47.5 9.3 251.9 25.2 39.2 8.1 20.3 315.8 328.8 87.6 31.4 271.3 67.6 31.9 227.2 120.3 28.8 27.6 22.7 22.2 6.0 39.5 34.2 42.4 3.2 18.5 32.3 37.0 19.7 30.5 49.3 17.5 33.0 19.1 27.3 41.2 43.5 39.4 11.4 35.6 PPT2 ENSG00000221988 "Palmitoyl-protein thioesterase 2" Q9UMR5 6 32153441-32163678 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 33.6;Smooth muscle cells: 27.8;Syncytiotrophoblasts: 23.3" "Cancer enhanced" "Detected in all" "melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 21.3;HEK 293: 27.9;SK-MEL-30: 29.4" HPA000414 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA000414: " "unprognostic (1.90e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.03e-5)" "unprognostic (1.62e-1)" "unprognostic (6.75e-3)" "unprognostic (2.92e-3)" "unprognostic (6.41e-3)" "unprognostic (7.12e-2)" "unprognostic (2.56e-3)" "unprognostic (5.28e-3)" "unprognostic (1.12e-2)" "unprognostic (2.75e-3)" "unprognostic (5.09e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.24e-3)" 19.0 18.0 1.1 2.1 1.1 0.1 18.7 1.1 4.8 26.5 1.0 23.7 1.6 22.0 2.6 28.2 21.7 0.0 24.5 1.1 1.1 22.1 13.9 14.3 1.7 1.1 1.2 46.2 14.3 0.0 13.7 3.9 1.1 17.2 1.5 6.2 14.9 0.0 19.0 29.4 14.9 1.3 1.1 13.3 21.0 8.3 1.1 1.9 14.6 0.2 1.0 18.1 24.2 1.3 0.0 0.0 0.0 0.4 21.3 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.2 1.6 0.7 5.3 2.6 5.0 0.0 0.0 27.9 4.0 0.0 0.0 0.0 3.5 1.8 4.0 1.6 0.0 7.3 3.8 0.0 14.9 0.0 1.8 1.7 13.0 4.6 0.0 0.0 0.9 0.0 6.3 5.8 0.0 14.3 0.0 1.6 5.4 8.7 5.2 29.4 15.2 0.0 3.7 0.8 0.0 11.4 0.0 0.0 0.8 12.6 3.0 5.8 2.2 3.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.7 0.0 0.1 1.1 1.1 1.1 4.8 1.1 1.1 1.1 1.2 1.1 1.1 1.1 1.3 9.4 0.0 0.5 0.0 0.7 3.3 2.9 2.6 5.7 12.4 4.2 2.9 6.8 2.8 2.8 3.7 16.7 14.5 4.4 2.4 1.9 1.8 0.3 4.5 4.3 7.6 4.9 17.4 0.0 3.0 9.2 6.3 1.5 5.0 0.0 33.6 6.4 4.4 3.0 3.3 0.0 2.6 2.0 1.3 1.3 1.1 4.1 1.1 7.2 0.0 0.2 9.5 3.1 0.0 0.0 1.8 3.8 3.0 1.7 1.4 1.4 3.1 0.6 6.1 0.0 3.6 27.8 4.0 6.7 4.4 2.3 23.3 1.4 5.0 3.0 1.5 PPY PNP ENSG00000108849 "Pancreatic polypeptide" P01298 17 43940804-43942476 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "pancreas: 174.4" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 40.5;Langerhans cells: 10.0;Pancreatic endocrine cells: 33.3" "Cancer enriched" "Detected in some" 132 "pancreatic cancer: 630.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 1.2" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.2" "Cell line enhanced" "Detected in some" "BEWO: 3.7;EFO-21: 3.2;U-2 OS: 3.9" "CAB016735, HPA032122" Enhanced "Secreted to blood" NA NA 70300 44000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB016735: , HPA032122: AB_2674164" "unprognostic (5.12e-3)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.65e-2)" "unprognostic (7.56e-3)" "unprognostic (8.13e-2)" "unprognostic (1.33e-1)" "unprognostic (7.78e-3)" "unprognostic (1.42e-1)" 0.1 0.3 0.0 0.2 0.0 2.1 0.0 0.0 0.1 0.0 0.0 2.5 1.1 0.3 4.2 0.0 0.1 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 0.0 174.4 6.9 0.0 0.1 0.0 0.0 7.3 0.0 0.0 0.0 0.0 6.7 0.6 0.0 0.0 0.1 0.9 0.3 0.0 0.5 1.3 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.7 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.5 0.0 3.9 0.4 0.5 0.0 0.3 0.9 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.1 0.0 0.0 40.5 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 10.0 2.8 0.0 0.6 1.8 0.0 0.2 0.0 0.0 0.0 0.0 33.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.5 0.0 0.0 0.3 0.0 PRAC2 "C17orf93, HOXB-AS5, HOXB13-AS1, NCRNA00253" ENSG00000229637 "PRAC2 small nuclear protein" D3DTV9 17 48723185-48724758 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 9.7;prostate: 13.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 36.2;Distal enterocytes: 17.5;Early spermatids: 32.9;Enteroendocrine cells: 31.9;Intestinal goblet cells: 15.5;Late spermatids: 60.5;Prostatic glandular cells: 20.2;Undifferentiated cells: 22.7;Urothelial cells: 30.1" "Cancer enriched" "Detected in many" 8 "prostate cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "PC-3: 49.3;REH: 20.0" "Intracellular and membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.26e-2)" "unprognostic (2.04e-1)" "unprognostic (1.63e-2)" "unprognostic (9.98e-2)" "unprognostic (3.27e-2)" "unprognostic (9.77e-2)" "unprognostic (8.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 13.3 9.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.4 2.5 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.5 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.2 49.3 20.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.2 0.0 2.8 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 32.9 0.0 0.0 0.1 31.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.3 60.5 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.4 0.0 20.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 22.7 30.1 PRADC1 "C2orf7, hPAP21, MGC13004, PAP21" ENSG00000135617 "Protease associated domain containing 1" Q9BSG0 2 73228010-73233239 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 126.6" "Cell type enhanced" "Detected in all" "Late spermatids: 144.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051066 Approved "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA051066: AB_2681333" "unprognostic (2.94e-1)" "unprognostic (1.93e-2)" "unprognostic (1.22e-1)" "unprognostic (1.12e-1)" "unprognostic (9.23e-2)" "unprognostic (3.93e-2)" "unprognostic (8.54e-2)" "unprognostic (9.08e-3)" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (1.09e-3)" "unprognostic (9.99e-3)" "unprognostic (3.56e-2)" "unprognostic (2.96e-1)" "unprognostic (4.89e-1)" "unprognostic (1.93e-1)" "unprognostic (9.23e-2)" 22.8 35.9 46.0 9.8 48.1 8.7 19.3 48.6 50.6 15.1 54.1 29.0 25.2 12.6 16.3 25.8 11.3 9.8 101.4 45.8 46.9 27.0 71.5 12.7 9.2 47.6 47.3 11.0 41.6 21.2 23.1 8.2 47.4 19.3 21.4 15.5 29.1 14.7 126.6 20.6 22.1 14.8 46.7 23.6 27.1 31.3 49.0 11.0 17.9 107.1 9.9 23.1 16.3 46.4 21.7 16.6 16.2 31.3 49.3 19.2 22.6 37.8 15.1 32.5 18.7 46.6 20.6 23.3 20.2 38.0 29.3 19.5 25.8 22.7 23.0 36.2 28.2 36.7 21.4 35.2 15.3 20.3 33.7 25.0 13.5 29.2 15.4 9.4 30.5 39.0 32.4 46.1 37.8 41.9 51.7 34.0 5.2 93.7 74.2 31.0 68.6 71.8 18.6 19.0 34.5 12.3 18.1 42.5 15.7 17.3 22.5 15.7 18.9 37.6 16.6 32.9 31.8 52.2 43.9 22.3 24.0 39.6 15.7 15.6 35.0 35.4 24.8 84.3 20.1 17.5 23.8 23.6 36.3 21.8 22.3 19.5 5.0 39.2 105.3 73.3 31.1 48.2 46.0 48.1 48.6 50.6 45.8 46.9 47.6 47.3 47.4 46.7 49.0 46.4 21.7 9.6 4.6 10.1 11.0 15.6 11.3 34.5 4.6 15.2 23.3 23.9 62.6 15.7 20.0 14.7 8.4 25.7 25.4 44.7 72.4 23.3 57.3 12.1 9.3 17.7 32.3 4.2 6.9 46.9 47.2 20.4 13.7 6.0 28.6 4.8 30.7 63.0 49.1 11.8 6.9 47.7 44.7 25.5 14.0 144.3 16.8 19.3 16.0 1.9 7.2 31.4 21.6 6.0 7.0 23.2 31.2 16.1 29.2 10.7 101.4 65.2 15.8 28.3 32.9 19.1 19.1 61.5 21.1 30.1 24.0 13.5 9.7 27.2 50.2 15.4 PRAP1 UPA ENSG00000165828 "Proline rich acidic protein 1" Q96NZ9 10 133347368-133352683 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 1135.4;liver: 675.2" "Cell type enriched" "Detected in some" 9 "Proximal enterocytes: 17736.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 348.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 34.2;Hep G2: 128.3" "HPA038713, HPA052451" Supported "Secreted to digestive system" NA NA 210000000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA038713: AB_10673117, HPA052451: AB_2681839" "unprognostic (1.63e-3)" "unprognostic (1.79e-2)" "unprognostic (1.09e-1)" "unprognostic (1.89e-3)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "unprognostic (8.90e-2)" "unprognostic (3.60e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" "unprognostic (4.35e-3)" "unprognostic (4.91e-2)" "unprognostic (8.23e-3)" "unprognostic (2.25e-1)" "unprognostic (3.15e-1)" "unprognostic (2.92e-2)" "unprognostic (2.22e-3)" 0.6 0.5 0.7 4.2 0.7 0.5 0.3 0.4 0.7 0.2 6.5 74.6 1053.8 0.8 0.1 0.4 0.7 2.6 0.3 0.6 0.4 145.4 675.2 0.2 1.5 1.2 0.7 0.4 0.1 0.1 0.8 0.1 1.1 0.3 35.7 0.0 1.7 0.3 0.2 1.3 1135.4 1.7 0.4 0.8 2.7 12.2 0.6 0.3 0.2 0.3 0.1 0.3 0.2 0.8 0.2 0.5 0.1 1.2 0.1 0.0 14.6 0.0 0.0 0.0 0.0 34.2 0.6 0.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.5 128.3 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 1.6 0.0 3.5 0.4 5.0 0.0 0.2 0.9 2.9 0.0 0.0 0.9 4.6 0.4 0.0 0.0 0.8 0.0 0.2 0.0 0.0 1.4 1.3 0.0 1.4 0.1 0.4 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.7 0.4 0.7 0.6 0.4 1.2 0.7 1.1 0.4 0.6 0.8 0.0 0.0 0.0 0.0 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 8.6 0.0 9.2 0.0 0.2 0.0 773.7 33.2 0.1 1.9 0.6 0.0 0.6 18.4 13.5 0.1 0.2 0.2 0.2 1.5 0.1 8.9 0.0 12.5 1021.3 0.2 0.0 0.0 676.2 0.0 20.9 0.0 7.3 1.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1815.7 1.5 0.0 0.1 17736.9 412.0 0.1 0.0 0.0 0.0 0.1 140.2 38.2 0.0 0.0 0.3 3.5 0.0 607.1 0.1 PRB1 "PM, PMF, PMS, PRB1L, PRB1M" ENSG00000251655 "Proline rich protein BstNI subfamily 1" 12 11351823-11395566 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 2529 "salivary gland: 16328.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" 0.0 0.0 0.1 0.0 0.3 2.4 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 6.4 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 16328.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRB2 "cP7, PRPPRB1, Ps" ENSG00000121335 "Proline rich protein BstNI subfamily 2" P02812 12 11391540-11501041 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 952 "salivary gland: 12081.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA 25000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.36e-1)" "unprognostic (1.01e-2)" "unprognostic (2.61e-1)" "unprognostic (2.07e-2)" "unprognostic (9.21e-2)" "unprognostic (5.51e-3)" "unprognostic (1.97e-4)" "unprognostic (1.51e-1)" 0.0 0.0 1.9 0.0 5.8 1.6 0.0 0.3 7.4 0.1 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.4 0.0 0.0 0.3 0.0 1.4 1.4 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 12081.4 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.6 1.9 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 5.8 0.3 7.4 6.1 0.4 1.4 1.4 1.2 0.1 1.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRB3 PRG ENSG00000197870 "Proline rich protein BstNI subfamily 3" Q04118 12 11265924-11269805 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1919 "salivary gland: 14225.0" "Cell type enhanced" "Detected in some" "Early spermatids: 8.8;Endometrial ciliated cells: 1.7;Glandular and luminal cells: 1.7;Late spermatids: 3.4" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0;lung cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 2.2" "Secreted to digestive system" NA NA 27000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 5: NTERA-2 - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.12e-2)" "unprognostic (1.34e-1)" "unprognostic (1.05e-3)" "unprognostic (1.51e-1)" "unprognostic (7.46e-3)" "unprognostic (4.12e-2)" "unprognostic (9.65e-2)" "unprognostic (1.94e-2)" "unprognostic (8.27e-2)" "unprognostic (9.98e-2)" "unprognostic (2.35e-1)" "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 14225.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.8 1.7 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 PRB4 ENSG00000230657 "Proline rich protein BstNI subfamily 4" 12 11307077-11310436 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 206 "salivary gland: 3664.2" "Cell type enhanced" "Detected in single" "Early spermatids: 1.9" "Group enriched" "Detected in some" 10 "lung cancer: 2.0;melanoma: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.05e-1)" "unprognostic (8.25e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3664.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRCD RP36 ENSG00000214140 "Photoreceptor disc component" Q00LT1 17 76527586-76553578 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "retina: 48.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 134.3;Cone photoreceptor cells: 152.2;Muller glia cells: 100.4;Rod photoreceptor cells: 551.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.6;Hep G2: 2.1;HSkMC: 1.1;SH-SY5Y: 2.4" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" "unprognostic (3.50e-2)" "unprognostic (1.83e-3)" "unprognostic (3.74e-1)" "unprognostic (1.31e-4)" "unprognostic (6.56e-2)" "unprognostic (4.07e-3)" "unprognostic (1.76e-1)" "unprognostic (2.07e-1)" "unprognostic (4.04e-2)" "unprognostic (2.45e-1)" "unprognostic (1.19e-6)" "unprognostic (1.03e-1)" "unprognostic (1.10e-1)" "unprognostic (8.94e-3)" "unprognostic (1.39e-2)" 1.0 0.6 0.2 0.4 0.1 0.0 1.1 2.8 0.7 1.5 1.5 0.5 0.4 0.9 0.0 0.3 1.0 0.2 1.5 0.1 0.3 0.6 0.2 0.7 0.7 1.3 0.6 0.6 0.3 0.2 0.2 0.5 1.4 0.9 0.1 48.0 0.5 0.3 0.4 0.5 0.5 0.1 0.2 1.1 0.3 0.4 0.4 0.0 0.7 0.0 0.2 1.3 1.3 0.3 0.0 0.0 0.0 0.0 0.7 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.1 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.8 0.7 0.1 0.3 1.3 0.6 1.4 0.2 0.4 0.3 8.5 0.0 0.0 0.7 13.5 0.5 0.2 0.6 0.0 134.3 0.1 0.5 5.4 0.0 0.7 0.0 152.2 0.1 1.3 0.0 0.0 0.2 4.3 0.3 0.4 7.8 0.0 0.0 2.1 0.0 0.0 5.3 0.0 0.0 0.0 0.2 1.1 0.0 0.1 37.0 4.9 0.0 0.0 0.0 1.1 11.0 6.2 0.5 7.2 2.8 0.1 100.4 0.0 0.5 26.0 0.2 0.0 1.9 1.8 0.2 0.0 0.2 0.3 551.3 6.6 10.5 3.4 3.3 0.9 0.1 0.3 0.3 1.2 1.1 0.0 0.1 PRCP "HUMPCP, PCP" ENSG00000137509 Prolylcarboxypeptidase P42785 11 82822936-82970584 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 348.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 463.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017065, HPA071115" Approved Supported Vesicles "Intracellular and membrane" NA NA 42000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA017065: AB_1855676, HPA071115: " "unprognostic (3.24e-1)" "unprognostic (2.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" "unprognostic (1.33e-2)" "unprognostic (9.22e-2)" "unprognostic (1.42e-1)" "unprognostic (7.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.70e-1)" "unprognostic (1.88e-2)" "prognostic favorable (2.65e-6)" "unprognostic (7.16e-2)" "unprognostic (1.73e-2)" "unprognostic (3.49e-1)" "unprognostic (4.07e-1)" 74.8 87.3 81.1 57.8 82.1 37.7 70.0 84.3 109.1 91.9 95.0 49.3 28.6 62.9 81.4 62.1 57.0 64.3 70.0 76.6 85.6 144.7 151.9 58.1 92.1 84.4 82.1 53.5 37.9 78.4 34.5 152.8 80.9 52.5 46.6 21.9 85.6 55.5 15.9 54.1 31.8 80.8 89.0 54.0 32.0 41.8 86.0 33.7 63.7 28.5 85.0 100.2 57.5 86.7 34.9 41.8 49.6 121.0 463.5 146.7 67.1 67.5 131.9 70.9 97.0 103.5 70.7 55.9 100.7 117.9 72.6 53.2 53.7 45.2 72.0 43.9 38.3 37.7 56.5 76.7 86.2 31.0 124.7 122.0 39.3 72.7 68.6 166.5 224.0 26.3 39.1 69.8 72.7 19.5 4.9 171.7 33.9 90.3 31.1 27.1 97.0 65.1 118.0 71.2 24.0 51.9 101.9 60.2 41.5 80.6 66.6 49.6 65.0 78.8 77.4 71.1 33.5 64.2 113.6 46.3 32.9 41.7 44.5 53.5 76.9 50.9 13.7 79.0 16.1 31.7 14.0 15.9 140.2 34.2 12.0 17.4 89.0 34.7 64.8 27.9 14.8 49.6 81.1 82.1 84.3 109.1 76.6 85.6 84.4 82.1 80.9 89.0 86.0 86.7 86.9 19.2 12.9 58.8 45.5 31.4 41.5 53.4 25.0 11.7 26.2 25.1 26.6 37.1 25.2 62.5 2.1 65.1 29.0 9.8 29.4 32.9 44.9 17.4 37.7 180.4 19.7 13.7 42.2 12.0 120.1 73.6 23.9 29.9 12.7 18.2 348.7 65.4 80.7 16.8 38.5 19.1 14.2 152.9 118.9 47.6 44.1 88.0 71.2 33.7 79.5 53.5 28.8 34.7 10.5 8.2 10.2 46.3 62.2 23.3 3.9 83.8 9.1 5.3 65.7 25.5 25.6 60.8 6.3 54.3 34.9 52.9 22.3 27.7 20.9 39.2 PRDM12 PFM9 ENSG00000130711 "PR/SET domain 12" Q9H4Q4 9 130664594-130682986 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "brain: 2.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Excitatory neurons: 1.1" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 23 "RH-30: 19.1" "Region enriched" "Detected in some" 7 "basal ganglia: 10.9" "Group enriched" "Detected in some" 26 "basal ganglia: 3.8;hypothalamus: 1.3" HPA043143 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA043143: AB_10806379" "unprognostic (3.25e-2)" "unprognostic (2.32e-1)" "unprognostic (3.40e-1)" "unprognostic (1.81e-4)" "unprognostic (7.90e-2)" "unprognostic (4.75e-3)" "unprognostic (2.48e-3)" "unprognostic (4.18e-2)" "unprognostic (4.61e-1)" "unprognostic (2.70e-1)" "unprognostic (6.43e-2)" "unprognostic (7.58e-2)" "unprognostic (4.03e-3)" "unprognostic (3.01e-2)" "unprognostic (4.79e-2)" "unprognostic (6.30e-4)" "unprognostic (1.40e-1)" 0.0 0.0 0.3 0.0 2.5 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.2 0.2 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.8 0.0 0.7 0.0 0.1 0.1 0.0 19.1 0.4 0.0 0.0 0.8 0.2 0.3 0.1 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.2 0.4 0.2 1.9 0.2 0.2 0.2 0.1 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.6 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 PRDM4 PFM1 ENSG00000110851 "PR/SET domain 4" Q9UKN5 12 107732871-107761272 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024322, HPA067437" Approved Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA024322: AB_1855691, HPA067437: AB_2685839" "unprognostic (4.64e-2)" "unprognostic (3.16e-3)" "unprognostic (1.73e-3)" "unprognostic (2.35e-1)" "unprognostic (1.94e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.86e-4)" "unprognostic (1.11e-3)" "prognostic unfavorable (7.66e-4)" "unprognostic (9.64e-2)" "unprognostic (9.06e-3)" "unprognostic (5.31e-2)" "prognostic favorable (3.15e-7)" "unprognostic (9.24e-2)" "unprognostic (1.09e-1)" "unprognostic (1.59e-1)" "unprognostic (2.62e-3)" 12.8 8.6 12.8 11.9 13.3 16.9 11.7 14.5 13.5 12.0 13.1 15.0 13.2 15.2 13.4 15.6 11.8 11.2 8.9 12.3 12.8 21.0 7.0 12.9 12.4 13.2 12.8 15.0 10.2 44.5 8.1 12.5 13.5 11.5 16.4 20.9 11.5 12.1 12.5 12.3 13.8 13.9 11.1 12.3 12.7 11.6 14.7 11.4 12.6 12.8 14.0 11.5 13.2 14.3 19.2 20.9 22.4 23.4 23.7 24.3 17.1 25.6 33.2 25.4 19.2 14.7 8.1 24.6 10.6 27.2 23.7 13.4 23.5 18.7 27.4 18.1 24.1 19.5 15.5 15.8 30.5 28.1 19.3 29.8 35.3 28.7 49.1 27.6 33.5 22.7 24.0 29.0 30.6 20.1 15.9 24.9 11.7 12.4 28.2 12.8 22.4 24.2 26.2 29.0 27.6 25.8 19.3 13.5 23.5 15.2 16.5 14.1 34.1 19.4 14.0 26.1 21.7 20.3 21.5 17.2 14.2 13.1 14.7 1.1 0.8 1.4 1.9 3.0 1.3 2.6 1.0 1.7 2.3 2.1 1.6 2.0 0.3 1.2 4.2 1.2 2.2 0.8 12.8 13.3 14.5 13.5 12.3 12.8 13.2 12.8 13.5 11.1 14.7 14.3 10.6 9.6 6.4 4.9 38.3 14.5 9.0 4.2 8.0 13.6 7.6 6.7 7.3 4.3 6.3 12.9 14.6 6.3 9.8 13.3 9.8 14.8 23.4 12.3 19.8 11.2 12.6 6.9 12.0 11.4 7.5 9.7 10.2 21.8 3.8 11.0 11.0 4.6 11.4 33.7 12.2 10.3 2.0 10.3 7.2 28.4 6.2 9.0 8.8 15.0 12.1 7.5 12.3 9.5 12.9 16.6 8.1 4.9 8.2 12.4 14.6 9.7 7.2 11.7 6.6 12.4 10.6 6.3 12.5 12.5 16.9 4.8 11.1 6.4 12.0 10.2 PRDM6 "KMT8C, PRISM" ENSG00000061455 "PR/SET domain 6" Q9NQX0 5 123089241-123194266 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.9;urinary bladder: 9.0" "Cell type enhanced" "Detected in some" "Astrocytes: 15.0;Endometrial stromal cells: 6.5;Excitatory neurons: 7.9;Fibroblasts: 10.7;Late spermatids: 7.1;Oligodendrocytes: 11.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.6;HEK 293: 5.2;HEL: 1.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.3" HPA030324 Uncertain Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA030324: AB_10670032" "unprognostic (2.33e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-3)" "unprognostic (3.12e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-2)" "unprognostic (4.66e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-7)" "unprognostic (9.30e-4)" "unprognostic (1.10e-1)" "unprognostic (3.43e-4)" "unprognostic (1.27e-1)" 0.7 0.1 0.2 0.3 0.2 0.0 0.6 0.2 0.3 0.9 0.6 4.9 0.2 0.7 0.1 0.6 0.4 3.3 0.5 0.1 0.2 0.3 0.1 2.9 0.0 0.3 0.4 1.9 0.3 0.1 0.3 4.2 0.4 1.3 1.0 0.2 0.1 0.1 0.1 0.2 0.6 0.7 0.3 0.0 0.6 0.3 0.2 0.0 0.8 0.2 0.2 9.0 0.6 0.3 0.0 0.0 0.0 0.3 0.3 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.1 5.2 1.1 0.5 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.2 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.1 0.2 0.3 0.4 0.4 0.3 0.2 0.3 0.5 0.0 0.0 15.0 0.0 1.9 0.1 0.0 0.0 1.0 0.6 0.3 1.4 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.1 3.3 0.6 6.5 0.5 0.0 0.0 7.9 0.2 0.3 10.7 0.0 0.5 0.0 2.4 0.0 0.5 0.8 0.0 6.4 0.1 0.0 0.8 3.5 7.1 2.1 0.4 3.6 4.7 0.8 0.2 0.0 3.0 11.0 0.1 0.0 1.2 0.1 0.2 0.0 0.8 0.2 1.0 0.0 0.7 2.2 2.3 4.4 0.2 1.3 0.4 0.4 6.1 0.0 0.1 PRDX4 AOE37-2 ENSG00000123131 "Peroxiredoxin 4" Q13162 X 23664262-23686397 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "pancreas: 1212.0" "Cell type enhanced" "Detected in all" "Late spermatids: 1007.4;Plasma cells: 810.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008659, CAB027389, CAB047362, HPA067039" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 4400000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" Cytosol "CAB008659: AB_1620984, CAB027389: , CAB047362: , HPA067039: " "unprognostic (3.82e-2)" "unprognostic (6.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.06e-3)" "unprognostic (1.64e-1)" "unprognostic (1.65e-2)" "unprognostic (1.29e-3)" "unprognostic (1.08e-1)" "unprognostic (8.32e-2)" "unprognostic (3.75e-2)" "unprognostic (2.97e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (7.44e-2)" "unprognostic (1.29e-1)" "unprognostic (3.56e-1)" "unprognostic (4.10e-2)" 85.7 84.6 25.2 53.9 27.4 34.3 74.9 28.7 36.6 82.3 40.2 72.7 64.0 68.1 19.5 62.5 66.1 64.7 108.6 24.7 28.7 41.8 277.2 47.1 58.7 30.6 26.8 81.2 1212.0 69.2 93.8 96.2 29.6 59.9 78.8 30.2 124.9 63.2 43.7 47.8 51.3 62.9 29.7 71.9 93.5 121.4 27.5 26.5 49.5 25.4 67.1 68.9 55.7 36.8 176.4 238.2 94.5 191.1 523.9 266.6 138.0 229.6 249.2 204.9 297.5 251.4 214.3 150.0 106.1 299.0 233.6 206.5 279.8 142.6 193.8 92.5 551.5 105.8 187.8 322.1 215.9 138.4 96.9 283.6 182.6 197.7 193.5 213.8 262.0 48.4 209.7 535.4 192.8 262.3 70.3 214.5 339.8 329.5 344.9 97.2 244.3 861.2 181.0 60.5 143.8 121.7 212.6 248.6 174.9 504.1 263.1 174.4 172.7 145.1 95.1 378.4 176.1 173.8 228.6 161.5 259.9 177.0 211.9 5.9 65.6 6.9 53.8 107.8 67.4 89.9 68.1 57.1 101.6 56.0 48.4 49.7 4.8 83.8 137.8 71.3 74.6 69.8 25.2 27.4 28.7 36.6 24.7 28.7 30.6 26.8 29.6 29.7 27.5 36.8 143.8 57.7 68.2 5.5 132.8 59.8 88.6 277.2 62.0 16.7 98.8 119.0 50.7 107.2 124.0 49.7 8.4 328.7 17.9 34.0 9.8 270.4 402.0 66.5 117.4 96.2 58.7 60.6 2.4 358.8 531.6 162.1 65.2 117.6 43.1 206.7 92.1 539.5 173.4 11.8 3.3 151.6 187.2 54.2 55.1 1007.4 252.5 47.1 199.3 1.9 75.2 55.0 27.8 8.5 7.3 241.4 44.1 144.0 810.1 174.6 61.2 54.2 89.9 21.7 144.7 79.2 185.3 258.2 251.7 83.3 52.1 258.6 42.0 311.8 115.7 73.1 PRDX5 "ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10" ENSG00000126432 "Peroxiredoxin 5" P30044 11 64318121-64321811 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 2430.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008661, HPA037915, HPA037916" Enhanced Supported Mitochondria NA NA 6900000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "CAB008661: AB_1620988, HPA037915: AB_2675735, HPA037916: AB_2675736" "unprognostic (2.75e-1)" "unprognostic (4.08e-1)" "unprognostic (1.33e-1)" "unprognostic (1.46e-1)" "unprognostic (9.43e-2)" "unprognostic (6.71e-3)" "unprognostic (1.08e-3)" "unprognostic (3.11e-1)" "unprognostic (9.30e-2)" "unprognostic (1.07e-3)" "unprognostic (1.57e-2)" "unprognostic (2.20e-1)" "prognostic favorable (1.24e-5)" "unprognostic (8.19e-2)" "unprognostic (2.30e-1)" "unprognostic (9.63e-2)" "unprognostic (5.03e-2)" 181.8 400.3 346.0 112.7 342.6 285.7 170.1 375.9 429.4 227.2 480.2 346.6 213.3 153.7 176.6 448.5 400.3 120.7 467.4 340.4 384.6 377.1 280.3 217.2 110.1 382.8 373.3 246.0 224.9 254.5 313.3 164.1 387.0 165.5 299.6 109.0 286.2 164.4 504.0 181.1 226.1 97.1 365.2 162.9 313.9 150.1 377.8 167.7 354.5 439.6 137.8 192.5 244.8 346.4 225.3 453.4 267.9 444.5 284.3 424.4 308.5 274.9 442.3 199.8 247.4 332.9 451.8 329.2 467.0 447.4 712.6 503.5 253.3 589.4 125.8 456.6 200.8 333.3 728.8 386.3 581.0 127.8 271.3 432.4 757.2 334.9 337.8 387.6 308.4 380.6 191.5 755.6 285.5 572.0 220.9 547.8 402.6 356.5 573.9 210.9 274.5 1178.8 760.1 442.9 224.7 424.9 230.8 506.8 818.8 254.3 370.5 283.3 298.3 281.8 258.6 326.7 123.1 383.1 490.8 392.4 340.7 253.7 223.6 703.9 465.4 630.7 251.0 432.9 218.3 393.5 229.0 205.1 369.8 409.0 224.5 225.9 802.3 368.5 399.0 487.9 297.1 639.6 346.0 342.6 375.9 429.4 340.4 384.6 382.8 373.3 387.0 365.2 377.8 346.4 213.7 266.0 463.4 17.6 182.1 326.5 760.2 1591.9 405.2 159.0 266.2 435.9 617.6 371.8 931.2 450.6 70.9 1122.2 185.8 846.1 1612.1 788.4 79.6 865.2 221.3 204.7 801.9 200.6 12.4 1039.2 1144.0 296.1 365.4 285.9 104.7 299.8 205.6 405.2 476.9 92.5 14.0 1041.6 1072.1 206.5 261.0 294.9 279.0 210.8 435.8 8.4 339.7 309.6 278.1 14.1 15.3 1487.3 641.3 226.8 288.9 401.3 922.4 1468.5 2430.7 150.3 197.2 176.2 433.1 150.2 333.9 482.8 257.7 978.9 165.2 713.3 1231.7 1077.1 PRELP "prolargin, SLRR2A" ENSG00000188783 "Proline and arginine rich end leucine rich repeat protein" P51888 1 203475806-203491352 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 206.6;Leydig cells: 100.6;Melanocytes: 192.1;Muller glia cells: 152.4;Peritubular cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.1" "Group enriched" "Detected in some" 5 "ASC diff: 18.0;BJ: 7.7;fHDF/TERT166: 11.7;SuSa: 5.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 82.4" HPA059225 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA059225: " "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.83e-2)" "unprognostic (6.56e-2)" "unprognostic (2.75e-2)" "unprognostic (1.61e-1)" "unprognostic (2.84e-2)" "unprognostic (3.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (5.62e-6)" "unprognostic (2.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.02e-4)" 114.8 23.4 12.6 4.2 14.2 0.5 77.5 7.7 20.2 126.7 20.0 136.4 6.6 147.7 7.6 41.3 108.6 40.4 212.0 11.6 10.0 25.3 15.6 124.7 8.0 10.2 8.2 128.2 13.1 2.5 22.6 12.0 9.4 73.6 8.9 21.5 32.7 77.1 35.6 56.4 61.0 51.4 8.3 44.2 41.3 7.2 10.3 3.2 60.4 36.9 15.9 147.8 92.9 9.4 0.2 0.2 0.5 0.1 18.0 0.5 0.4 7.7 1.0 0.2 0.2 0.0 0.1 1.2 0.6 11.7 0.1 0.6 0.2 0.3 0.3 0.0 0.1 0.2 0.5 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.2 2.1 0.0 0.4 0.2 0.4 1.3 0.1 0.1 0.5 0.4 0.3 0.1 0.4 0.2 0.4 0.0 0.3 1.0 0.2 0.2 0.2 0.8 5.2 0.2 0.1 0.6 0.5 0.2 0.3 0.1 0.2 0.3 1.2 0.1 0.2 0.5 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 12.6 14.2 7.7 20.2 11.6 10.0 10.2 8.2 9.4 8.3 10.3 9.4 8.8 0.0 5.8 5.2 0.9 18.2 1.0 0.0 2.2 3.6 4.2 5.1 7.4 1.5 0.6 0.0 2.1 0.1 0.3 0.1 0.0 0.0 1.1 0.6 1.7 15.6 0.0 2.7 1.6 0.0 0.1 206.6 4.6 1.6 5.1 0.2 22.9 0.3 0.3 1.7 0.2 0.0 0.0 0.3 19.2 5.3 100.6 0.9 192.1 22.5 0.0 152.4 0.0 7.5 0.5 0.0 0.0 199.7 0.4 0.6 0.0 0.1 1.5 8.9 26.3 9.6 38.3 3.1 2.4 1.6 9.9 0.3 1.6 0.1 0.0 1.3 PRF1 "HPLH2, P1, PFP" ENSG00000180644 "Perforin 1" P14222 10 70597348-70602759 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Cytolysis "Cancer-related genes, Disease variant, Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.6;lung: 16.5;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in some" "dendritic cells: 542.1;NK-cells: 1231.7;T-cells: 265.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 900.4;MAIT T-cell: 628.8;memory CD8 T-cell: 499.1;naive CD8 T-cell: 313.0;NK-cell: 656.8" "Group enriched" "Detected in all" 50 "NK-cells: 656.8;T-cells: 900.4" "Cell line enriched" "Detected in some" 11 "HDLM-2: 240.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002436, HPA037940" Approved Approved Cytosol "Intracellular and membrane" NA NA 2100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB002436: AB_563955, HPA037940: AB_2675747" "unprognostic (6.11e-3)" "unprognostic (1.26e-2)" "unprognostic (1.71e-1)" "prognostic favorable (2.09e-4)" "unprognostic (1.87e-2)" "prognostic favorable (3.54e-4)" "unprognostic (6.98e-3)" "unprognostic (2.62e-1)" "unprognostic (1.44e-3)" "unprognostic (1.69e-2)" "unprognostic (5.22e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.08e-5)" "unprognostic (7.38e-2)" "unprognostic (2.70e-1)" "unprognostic (7.97e-3)" "unprognostic (5.22e-3)" 5.0 2.0 0.7 7.6 0.7 28.6 2.7 0.7 1.3 1.3 1.3 2.2 2.3 3.5 1.1 1.9 1.9 4.2 2.2 0.6 0.6 1.7 6.3 16.5 20.3 1.4 0.7 1.0 1.0 0.5 0.9 2.7 1.0 1.5 1.4 0.0 2.3 1.2 2.6 0.9 5.2 2.0 1.3 49.4 4.7 0.6 1.0 5.8 2.6 1.5 4.9 3.8 1.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 240.1 0.0 1.4 0.0 7.4 0.0 0.3 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 22.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 5.2 1.9 0.9 900.4 1.7 628.8 4.0 125.8 499.1 2.0 3.5 52.1 313.0 15.4 656.8 2.6 2.9 108.8 587.5 0.7 0.7 0.7 1.3 0.6 0.6 1.4 0.7 1.0 1.3 1.0 1.0 3.1 3.2 13.6 0.0 4.4 0.4 0.1 0.0 0.6 0.0 0.5 0.5 0.8 1.5 2.5 0.0 0.0 0.2 542.1 0.1 0.0 0.3 0.0 0.2 0.3 1.9 0.0 19.0 0.0 0.0 0.1 2.1 7.7 0.4 8.8 0.0 10.8 2.7 0.1 0.0 0.0 0.0 0.0 7.8 2.3 0.0 0.0 5.7 0.0 1.9 7.4 0.0 1231.7 0.0 0.1 0.0 0.0 0.0 88.5 0.1 0.1 1.6 1.5 0.0 0.0 1.1 0.8 0.0 0.0 0.5 0.9 0.7 265.4 0.0 0.1 0.0 PRG2 "BMPG, MBP, proMBP" ENSG00000186652 "Proteoglycan 2, pro eosinophil major basic protein" P13727 11 57386780-57390650 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Immunity "Antibiotic, Antimicrobial, Heparin-binding" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "placenta: 2616.3" "Group enriched" "Detected in some" 10 "Erythroid cells: 44.3;Extravillous trophoblasts: 107.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 36 "basophil: 7.2" "Lineage enriched" "Detected in single" 73 "granulocytes: 7.2" "Group enriched" "Detected in some" 62 "HL-60: 3328.5;HMC-1: 5009.7;NB-4: 10560.9" "Not detected" "Not detected" HPA038515 Supported "Secreted in female reproductive system" NA NA 100000000 "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 24: NB-4 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA038515: AB_10675800" "unprognostic (7.32e-2)" "unprognostic (1.68e-1)" "unprognostic (3.39e-2)" "unprognostic (3.49e-1)" "unprognostic (8.62e-4)" "unprognostic (4.77e-3)" "unprognostic (3.20e-2)" "unprognostic (4.17e-2)" "unprognostic (2.26e-2)" "unprognostic (5.19e-3)" "unprognostic (2.17e-1)" "unprognostic (1.40e-11)" "unprognostic (4.26e-2)" "unprognostic (4.52e-3)" "unprognostic (6.47e-2)" "unprognostic (2.32e-1)" 0.7 0.0 0.0 0.1 0.0 215.8 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 2.5 1.1 1.4 0.0 0.0 0.3 3.8 0.0 0.2 2616.3 0.0 0.0 0.4 0.0 0.9 0.0 0.2 2.1 0.4 0.5 0.0 3.0 0.3 0.0 0.0 8.7 0.2 0.0 0.2 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.0 101.3 0.0 0.0 0.2 3328.5 5009.7 0.2 0.0 0.0 0.0 0.0 0.0 0.2 9.0 0.6 0.0 0.0 0.8 10560.9 0.0 0.0 0.0 0.3 0.8 1.0 0.0 0.0 1.6 4.2 0.4 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.3 0.8 0.0 0.5 0.0 0.4 0.2 0.4 0.3 7.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 44.3 0.0 0.0 107.2 0.5 0.0 0.0 6.3 0.0 0.0 0.1 7.2 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.7 0.0 0.0 0.0 0.0 PRG3 "MBP2, MBPH" ENSG00000156575 "Proteoglycan 3, pro eosinophil major basic protein 2" Q9Y2Y8 11 57376769-57381150 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "bone marrow: 48.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 46 "HMC-1: 198.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 3.5" HPA064183 Enhanced "Secreted in other tissues" NA NA 680000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "HPA064183: AB_2685205" 0.0 0.0 0.0 0.0 0.0 48.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 198.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRG4 "bG174L6.2, CACP, FLJ32635, HAPO, JCAP, MSF, SZP" ENSG00000116690 "Proteoglycan 4" Q92954 1 186296279-186314567 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 93.2;liver: 185.7" "Group enriched" "Detected in some" 15 "Fibroblasts: 320.6;Hepatocytes: 364.7" "Cancer enriched" "Detected in many" 10 "liver cancer: 28.4" "Region enriched" "Detected in single" 33 "hypothalamus: 30.8" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.2" "Lineage enriched" "Detected in single" 12 "T-cells: 1.2" "Cell line enriched" "Detected in some" 6 "ASC diff: 284.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" CAB054258 Supported "Secreted to extracellular matrix" NA NA 4300000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB054258: " "unprognostic (8.67e-2)" "unprognostic (2.28e-1)" "unprognostic (1.82e-3)" "unprognostic (1.98e-1)" "unprognostic (1.77e-1)" "unprognostic (7.87e-2)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (1.28e-1)" "unprognostic (1.53e-1)" "unprognostic (5.03e-2)" "unprognostic (4.11e-1)" "unprognostic (1.91e-13)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (1.60e-3)" "unprognostic (7.05e-3)" 93.2 2.3 0.0 2.3 0.0 0.3 15.1 0.4 0.9 0.6 3.9 1.2 0.0 0.6 0.9 0.3 20.0 0.4 31.7 0.0 30.8 0.2 185.7 26.4 0.4 0.0 0.0 2.1 1.5 0.0 2.1 0.0 0.1 0.6 0.1 0.1 3.9 0.1 9.5 7.7 0.4 0.3 0.2 0.7 1.4 0.2 0.2 0.3 1.7 8.1 0.3 2.6 0.5 0.0 0.0 0.1 0.0 0.0 284.6 11.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 1.1 0.1 0.2 0.2 0.0 26.2 0.0 44.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.7 1.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.9 0.0 30.8 0.0 0.0 0.1 0.2 0.2 0.0 5.1 22.4 16.2 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 2.7 10.0 21.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.2 3.7 4.1 0.0 2.7 0.0 0.0 0.0 320.6 0.0 0.8 16.4 0.0 6.4 364.7 0.1 0.0 0.1 0.0 0.0 9.4 1.9 0.8 0.0 2.8 1.8 0.0 0.1 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.1 0.1 0.0 0.0 10.9 0.0 0.0 3.5 1.5 0.0 0.3 0.0 1.1 0.0 2.3 0.1 0.0 0.1 PRH1 Pa ENSG00000231887 "Proline rich protein HaeIII subfamily 1" 12 10824960-11171608 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 204 "salivary gland: 12076.2" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2472.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.8;OE19: 1.3" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.39e-1)" "unprognostic (1.38e-1)" "unprognostic (3.83e-3)" "unprognostic (3.61e-1)" "unprognostic (1.66e-1)" "unprognostic (3.70e-1)" "unprognostic (6.81e-2)" "unprognostic (6.85e-2)" "unprognostic (7.35e-3)" "unprognostic (2.14e-1)" "unprognostic (5.00e-3)" "unprognostic (1.16e-1)" "unprognostic (1.61e-2)" "unprognostic (1.50e-1)" "unprognostic (1.13e-1)" "unprognostic (1.73e-2)" "unprognostic (2.68e-1)" 0.9 1.8 0.4 0.1 0.4 0.9 1.2 0.2 0.7 1.5 0.1 0.9 0.0 1.2 0.0 11.2 0.9 0.0 1.6 0.4 0.3 1.5 2.2 1.4 0.0 0.5 0.4 1.8 6.2 0.3 4.4 1.2 0.7 1.5 0.0 0.2 12076.2 0.1 0.4 0.8 1.0 0.0 0.2 1.3 0.9 59.2 0.4 0.4 1.6 0.0 0.0 0.9 1.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.6 0.0 0.2 1.8 0.2 0.0 0.0 0.7 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.2 0.0 1.3 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.4 0.4 0.2 0.7 0.4 0.3 0.5 0.4 0.7 0.2 0.4 1.1 16.7 9.6 2.0 0.0 7.0 0.0 0.5 0.0 0.6 1.9 13.8 11.4 0.9 0.0 4.3 23.9 4.2 1.0 15.2 1.2 1.9 11.4 586.1 5.9 12.7 5.4 1.8 2.7 0.0 6.9 0.4 7.0 0.5 4.9 0.0 45.8 4.6 0.7 0.9 3.3 0.0 0.4 0.0 1.0 0.0 2472.1 7.8 6.7 0.0 0.0 10.7 2.6 1.0 0.0 0.0 15.3 0.3 6.4 3.2 0.6 0.6 3.9 0.7 1.3 0.0 0.8 8.7 7.9 4.6 0.2 0.0 0.8 8.8 46.8 1.2 0.3 PRH2 Pr ENSG00000134551 "Proline rich protein HaeIII subfamily 2" P02810 12 10929236-10934845 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 909 "salivary gland: 23048.6" "Group enriched" "Detected in some" 107 "Early spermatids: 35.5;Late spermatids: 136.2" "Cancer enriched" "Detected in some" 11 "head and neck cancer: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA 21000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (3.65e-2)" "unprognostic (3.59e-1)" "unprognostic (1.25e-1)" "unprognostic (5.52e-2)" "unprognostic (3.83e-2)" "unprognostic (9.49e-2)" "unprognostic (1.01e-2)" "unprognostic (7.37e-2)" "unprognostic (1.63e-5)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (4.26e-1)" "unprognostic (3.43e-2)" 0.0 0.1 0.5 0.0 0.9 1.7 0.1 1.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 19.2 0.0 0.0 4.6 0.6 0.8 0.0 0.4 4.9 0.0 1.2 0.7 4.4 25.3 0.0 0.3 2.6 1.2 0.1 0.0 0.6 23048.6 0.0 0.0 0.9 0.0 0.0 0.5 0.1 0.0 3.9 0.8 0.0 0.1 0.0 0.1 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 1.0 1.0 0.6 0.8 1.2 0.7 1.2 0.5 0.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 35.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 136.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRIMPOL "CCDC111, FLJ33167" ENSG00000164306 "Primase and DNA directed polymerase" Q96LW4 4 184649667-184694963 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 24.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 24.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054372 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol Nucleoplasm "HPA054372: AB_2682466" "unprognostic (1.68e-1)" "unprognostic (1.27e-3)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (2.67e-2)" "unprognostic (4.75e-2)" "unprognostic (2.02e-2)" "unprognostic (3.34e-2)" "unprognostic (3.32e-3)" "unprognostic (5.86e-2)" "unprognostic (2.52e-2)" "unprognostic (5.02e-1)" "unprognostic (3.04e-1)" "unprognostic (3.04e-2)" "unprognostic (3.81e-1)" "unprognostic (1.49e-1)" "unprognostic (1.05e-1)" 7.2 8.0 4.0 6.0 4.9 5.5 8.9 7.6 4.2 8.5 4.4 7.9 4.7 10.7 8.2 7.0 8.9 6.9 7.0 3.6 4.1 5.7 6.8 7.5 7.9 4.3 4.1 12.1 4.8 6.8 4.6 6.6 4.3 7.1 8.6 7.2 4.7 8.2 4.7 6.6 6.7 9.2 4.2 8.6 5.9 5.5 4.3 8.6 7.6 5.3 6.4 6.4 5.3 5.6 13.1 5.7 13.2 15.0 17.5 23.2 8.9 13.8 21.8 22.9 19.9 4.4 13.3 7.5 5.0 10.6 12.6 7.9 11.3 14.6 24.0 15.9 5.3 7.8 7.8 5.3 11.4 6.4 11.5 14.5 11.4 21.2 13.7 13.4 12.6 20.7 16.5 24.0 16.5 4.4 13.3 5.4 4.3 5.8 4.6 12.3 9.4 9.0 11.8 7.8 9.4 11.9 8.3 2.1 15.2 10.4 6.6 12.3 6.8 7.5 9.7 5.9 8.9 13.4 10.2 3.8 11.1 8.5 18.6 11.2 2.5 24.0 3.8 2.4 5.6 3.6 3.6 3.9 3.2 3.7 3.0 3.0 1.2 4.7 5.6 2.7 4.6 3.1 4.0 4.9 7.6 4.2 3.6 4.1 4.3 4.1 4.3 4.2 4.3 5.6 7.7 6.4 8.6 23.5 6.7 9.6 9.5 10.0 9.1 6.2 10.1 6.3 2.6 7.2 10.4 5.5 0.0 14.3 8.1 5.9 5.9 7.7 5.5 9.0 11.1 7.3 6.7 17.5 13.9 5.2 10.0 9.7 8.2 6.3 15.2 12.0 8.9 7.5 9.7 8.4 26.9 58.8 6.1 14.8 6.4 5.7 12.5 9.5 8.8 19.7 6.5 11.1 6.2 27.2 28.1 3.7 10.4 9.1 8.6 4.0 7.2 5.7 15.4 8.2 13.1 11.1 9.0 18.8 13.1 6.9 9.8 4.9 8.9 5.7 8.0 5.4 PRKAG1 ENSG00000181929 "Protein kinase AMP-activated non-catalytic subunit gamma 1" P54619 12 49002274-49018807 "FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 339.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077805 Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA077805: AB_2686855" "unprognostic (3.24e-2)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (1.63e-2)" "unprognostic (3.44e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (2.84e-7)" "unprognostic (1.45e-1)" "unprognostic (4.68e-2)" "unprognostic (1.93e-2)" "unprognostic (5.35e-2)" "unprognostic (8.49e-2)" "prognostic favorable (1.83e-4)" "unprognostic (3.40e-1)" "unprognostic (2.57e-1)" "unprognostic (1.97e-2)" "unprognostic (5.57e-2)" 42.8 54.5 36.4 29.8 40.5 47.4 50.5 39.9 46.3 37.6 41.9 40.7 32.6 32.9 59.1 44.2 33.4 31.3 80.9 38.2 38.6 50.5 49.4 30.8 38.7 34.5 35.5 25.6 37.4 59.1 33.9 35.1 36.5 37.7 47.8 42.3 36.1 39.9 122.7 43.0 29.9 44.8 33.5 28.6 33.5 33.5 34.9 41.8 37.7 112.4 50.8 40.1 30.8 41.5 79.8 45.8 50.5 76.3 157.8 141.6 33.2 85.5 117.4 84.4 55.7 50.9 66.1 50.4 72.9 98.9 53.9 65.4 42.5 115.6 80.4 69.6 57.1 70.4 66.5 34.2 120.2 97.7 54.6 110.0 94.6 65.9 141.4 123.6 90.3 67.6 60.1 70.0 108.6 52.8 45.8 31.5 29.1 339.6 96.8 24.1 53.3 59.7 114.0 67.6 42.1 57.7 61.0 99.1 142.5 39.7 134.1 49.5 72.5 44.4 52.3 87.7 63.5 109.1 113.3 36.0 89.3 69.9 34.5 87.3 59.8 59.9 53.0 58.7 50.0 51.9 46.1 47.6 68.7 51.3 41.3 43.0 70.9 71.8 56.0 45.2 66.8 73.0 36.4 40.5 39.9 46.3 38.2 38.6 34.5 35.5 36.5 33.5 34.9 41.5 20.2 9.6 22.7 16.6 31.2 20.0 30.3 64.5 11.4 29.2 24.3 20.8 49.8 18.6 29.9 36.8 37.5 65.6 30.5 24.5 76.3 48.3 11.3 11.4 21.3 21.9 21.0 30.3 18.1 46.4 57.7 26.7 15.8 12.9 21.5 31.4 30.4 23.2 52.2 15.2 24.1 31.6 63.1 36.2 26.5 15.7 36.7 26.7 37.4 9.4 55.5 41.6 55.6 23.1 21.1 47.8 16.5 27.1 25.0 24.2 38.6 69.3 19.2 30.1 19.7 18.5 27.5 49.3 43.9 19.1 26.0 67.0 26.3 33.6 32.2 23.6 PRKAR1B ENSG00000188191 "Protein kinase cAMP-dependent type I regulatory subunit beta" P31321 7 549197-727650 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 175.7" "Cell type enhanced" "Detected in many" "Early spermatids: 62.3;Excitatory neurons: 78.7;Inhibitory neurons: 61.1;Late spermatids: 130.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NTERA-2: 128.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026719 Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 25: Spermatids - Spermatogenesis" "HPA026719: AB_1855419" "unprognostic (4.90e-2)" "unprognostic (4.92e-2)" "unprognostic (2.69e-1)" "unprognostic (4.34e-2)" "unprognostic (1.74e-3)" "unprognostic (1.02e-3)" "unprognostic (3.28e-2)" "unprognostic (4.24e-2)" "unprognostic (1.73e-1)" "unprognostic (1.41e-2)" "unprognostic (2.01e-3)" "unprognostic (1.95e-1)" "unprognostic (3.38e-3)" "unprognostic (5.18e-2)" "unprognostic (2.64e-1)" "unprognostic (9.23e-2)" "unprognostic (2.00e-1)" 12.0 11.0 79.6 7.5 99.4 8.8 12.4 0.0 175.7 17.6 0.0 19.4 12.3 23.5 3.7 12.0 15.8 7.6 17.1 105.2 76.3 15.9 12.9 12.4 9.7 62.9 15.9 28.1 6.5 8.9 35.7 5.5 53.3 12.6 6.5 19.3 7.3 8.3 7.3 8.0 13.4 8.7 4.2 22.8 11.3 15.4 52.5 10.2 8.2 3.8 5.3 10.2 13.5 88.9 83.0 54.2 8.0 19.7 5.1 4.6 22.8 15.9 7.3 10.0 5.7 97.9 17.5 63.2 11.3 7.2 33.1 60.3 27.0 30.6 4.2 12.8 20.1 4.3 33.3 65.4 9.7 39.7 9.5 12.8 9.2 6.8 18.7 11.1 10.8 15.7 61.6 11.8 9.2 77.8 47.5 26.5 128.0 22.1 23.0 30.9 1.6 27.4 25.0 20.8 106.0 81.5 41.2 39.2 32.0 3.2 20.1 14.6 13.0 4.4 9.9 6.0 32.3 7.7 23.4 41.0 8.2 29.8 59.5 1.8 2.4 0.0 5.0 3.0 7.7 7.4 8.9 7.7 2.8 10.0 13.8 13.3 0.9 4.6 1.2 6.6 6.6 10.5 79.6 99.4 0.0 175.7 105.2 76.3 62.9 15.9 53.3 4.2 52.5 88.9 18.3 3.2 4.4 12.4 7.3 3.8 7.4 6.0 6.2 11.1 9.0 12.8 13.1 4.3 5.0 5.5 4.2 4.0 7.0 10.1 25.4 4.1 62.3 4.5 6.5 15.2 4.2 13.5 78.7 3.4 5.8 8.2 10.7 4.4 7.0 55.0 16.4 8.5 8.9 53.8 61.1 10.9 2.0 6.2 8.6 130.0 11.8 8.7 7.2 15.0 1.6 7.3 5.2 24.1 7.5 7.7 14.1 15.4 8.2 5.6 20.7 24.5 1.4 6.3 0.0 12.8 9.0 15.6 11.1 10.7 4.7 3.4 9.1 12.0 15.5 5.0 PRKCSH "G19P1, GIIB, PCLD, PLD1, VASAP-60" ENSG00000130175 "Protein kinase C substrate 80K-H" P14314 19 11435284-11450968 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004465, HPA041940, HPA043560" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 55000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 50: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum" "CAB004465: AB_626622, HPA041940: AB_2677758, HPA043560: AB_2678553" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (2.45e-2)" "unprognostic (2.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.63e-2)" "unprognostic (2.52e-2)" "unprognostic (5.52e-2)" "unprognostic (1.16e-1)" "unprognostic (2.07e-3)" "unprognostic (1.28e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (7.69e-4)" "unprognostic (1.63e-3)" "unprognostic (2.10e-1)" "unprognostic (3.44e-1)" "unprognostic (1.18e-1)" 115.3 107.6 76.4 81.2 86.7 169.6 117.6 85.1 97.6 144.0 91.4 119.7 120.0 123.0 113.0 106.5 126.2 92.0 90.4 76.4 82.0 108.8 159.9 105.5 93.3 89.9 83.9 196.9 186.2 116.3 118.3 108.8 85.9 108.5 98.9 46.6 145.9 97.8 74.8 129.3 121.7 78.5 79.6 111.2 124.9 88.5 83.3 83.9 135.5 44.9 86.2 109.9 122.6 88.8 274.8 216.7 211.6 391.5 351.2 426.4 241.5 305.5 387.6 331.5 302.7 328.3 327.5 204.4 478.1 409.2 165.4 283.4 226.3 309.6 292.1 193.3 173.5 178.0 269.4 268.8 258.0 263.0 236.4 404.5 228.6 312.5 261.4 425.6 232.8 210.1 204.8 422.4 289.0 470.1 187.9 322.1 485.0 129.7 283.3 201.8 215.3 505.6 223.2 260.1 146.9 291.5 282.3 280.4 280.5 200.8 292.5 296.7 263.6 437.1 198.2 416.0 361.0 471.9 575.3 132.3 330.1 276.8 306.5 38.8 47.2 45.1 37.9 36.2 42.6 35.9 31.8 36.4 36.1 38.7 30.2 33.1 56.3 32.8 41.2 75.7 37.5 39.5 76.4 86.7 85.1 97.6 76.4 82.0 89.9 83.9 85.9 79.6 83.3 88.8 45.2 12.8 16.9 15.3 65.1 41.8 72.2 90.0 39.9 18.2 56.9 47.5 10.5 71.4 44.9 64.4 33.3 174.9 54.6 152.0 33.2 88.7 18.1 47.4 65.0 52.0 58.8 40.6 12.3 127.5 189.1 62.6 70.3 67.2 41.9 104.5 60.3 86.4 93.4 10.1 12.5 123.2 65.1 80.0 43.4 55.9 78.6 59.3 53.4 14.0 81.4 59.8 61.8 6.0 39.0 89.0 132.8 72.6 91.4 45.9 187.8 62.7 32.7 30.2 39.5 39.8 52.0 36.8 55.2 49.5 37.8 143.5 55.5 84.2 128.2 66.6 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 362.1;Excitatory neurons: 147.4;Inhibitory neurons: 171.1;Microglial cells: 89.0;Oligodendrocyte precursor cells: 390.6" "Cancer enhanced" "Detected in all" "prostate cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 21.6;fHDF/TERT166: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favorable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.89e-1)" 8.0 9.6 5.6 2.2 8.0 0.0 7.7 6.5 6.7 6.4 3.7 9.5 1.0 7.9 3.5 2.1 6.5 4.4 6.1 7.5 7.5 17.5 1.6 7.5 0.3 8.6 8.6 11.2 5.4 10.6 5.6 1.9 8.7 14.7 1.3 4.7 2.9 9.3 1.6 2.8 3.6 6.3 8.9 2.3 4.6 11.7 8.1 2.4 5.9 2.6 0.5 13.1 4.6 10.3 0.0 4.4 4.8 3.1 21.6 16.5 0.1 14.1 10.4 16.7 7.3 0.0 0.3 0.0 1.9 19.4 4.0 0.1 7.9 2.1 6.8 0.0 6.2 0.0 0.0 0.5 8.8 0.0 0.1 18.4 0.3 1.4 1.5 6.1 2.6 0.0 1.4 0.4 17.4 1.8 0.0 0.0 2.6 0.0 9.6 0.0 6.3 5.2 9.7 6.6 4.3 13.0 2.6 0.0 4.5 4.6 0.0 0.1 5.6 13.6 6.7 1.0 3.7 0.0 0.0 0.0 3.5 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.0 6.5 6.7 7.5 7.5 8.6 8.6 8.7 8.9 8.1 10.3 4.6 0.0 7.4 362.1 0.2 0.5 4.8 0.4 0.6 1.4 1.4 1.5 1.2 10.0 0.0 12.9 6.2 0.0 0.0 0.1 29.4 2.4 39.5 2.8 9.2 6.1 3.0 2.7 147.4 4.2 0.1 6.4 0.5 8.4 0.0 18.7 10.8 2.5 0.2 1.7 171.1 0.2 0.0 1.6 0.9 16.9 7.5 0.7 7.2 89.0 0.0 16.7 0.0 390.6 76.6 2.0 0.1 12.8 0.4 12.4 0.2 4.5 0.1 2.9 0.0 13.3 4.5 3.2 7.8 0.0 0.9 0.3 0.6 29.6 0.1 1.3 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/84: 149.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favorable (9.15e-4)" 29.0 11.5 7.2 23.6 7.3 29.4 29.3 5.4 7.7 26.6 12.5 20.3 17.1 21.8 4.7 27.5 24.1 11.2 13.8 6.1 6.0 19.2 13.8 34.3 31.1 10.0 6.3 21.8 19.1 8.3 24.0 11.1 6.8 23.9 7.1 4.4 24.7 10.0 8.0 46.8 29.9 6.0 6.0 54.3 20.3 6.6 7.7 25.6 28.9 4.8 21.2 19.5 26.9 6.6 19.6 34.5 12.8 16.6 7.3 6.4 15.1 11.5 13.2 19.6 19.7 19.7 21.0 22.3 16.3 13.2 13.2 27.5 9.5 26.0 5.9 19.8 17.5 25.9 11.5 10.2 12.8 21.2 34.7 11.0 15.8 12.7 9.8 12.8 30.1 21.5 14.6 35.4 7.0 23.8 32.7 53.1 9.7 27.4 17.4 25.8 5.8 37.5 11.4 32.7 7.7 22.4 18.8 18.8 4.6 10.6 11.6 7.5 17.6 8.7 18.8 7.1 10.0 31.8 149.1 13.5 8.5 17.7 11.0 0.6 0.7 2.6 3.9 0.7 3.3 4.3 3.9 4.3 0.3 4.1 3.3 3.3 5.3 2.2 0.5 0.0 2.9 1.5 7.2 7.3 5.4 7.7 6.1 6.0 10.0 6.3 6.8 6.0 7.7 6.6 37.8 9.6 9.9 5.9 46.5 22.0 32.0 13.2 22.8 6.4 13.9 11.3 17.2 12.8 13.0 9.2 0.0 13.8 17.5 43.6 7.9 18.6 1.2 15.3 6.7 37.2 21.6 4.0 6.5 28.2 13.8 9.6 23.4 15.0 14.5 14.1 37.1 8.5 9.0 1.7 2.8 21.7 4.1 12.3 11.4 3.1 11.8 8.3 12.4 11.2 9.3 6.5 42.2 4.0 3.1 29.5 35.1 6.8 47.0 22.9 34.1 9.3 15.6 4.4 13.1 6.1 7.6 2.9 17.9 21.2 26.7 29.7 31.9 6.6 15.3 30.2 PRKD3 "EPK2, PRKCN" ENSG00000115825 "Protein kinase D3" O94806 2 37250502-37324833 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 152.1;U-266/84: 159.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029529 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA029529: AB_10602082" "unprognostic (1.39e-1)" "unprognostic (7.34e-2)" "prognostic favorable (4.84e-4)" "unprognostic (1.23e-2)" "unprognostic (5.61e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (2.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.81e-1)" "unprognostic (7.62e-3)" "unprognostic (2.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.35e-1)" 15.1 19.9 6.1 18.1 6.8 8.7 14.4 7.8 7.3 19.3 3.9 16.4 8.2 18.9 13.8 10.7 9.9 13.3 9.8 6.0 7.5 12.0 10.1 14.7 29.1 7.2 7.1 18.0 9.1 11.7 6.5 14.9 7.8 11.7 11.0 41.6 10.5 12.5 14.9 12.2 10.3 16.2 7.6 23.4 12.4 23.3 8.1 20.7 13.4 12.1 28.9 15.5 9.5 7.1 38.8 14.3 44.4 36.1 33.2 55.1 31.5 25.0 48.8 29.1 28.7 23.4 14.0 58.5 20.1 39.6 43.2 15.0 31.1 31.9 39.0 72.3 38.7 39.2 24.4 17.8 13.8 26.2 21.5 26.0 16.2 46.2 29.7 26.6 52.6 19.9 32.3 70.9 33.8 6.1 11.6 21.6 45.4 0.4 14.2 40.8 67.9 51.8 18.9 42.1 32.5 81.0 24.6 13.9 152.1 22.8 15.1 25.1 47.7 80.0 40.5 31.5 28.5 78.1 159.7 68.2 27.8 11.2 48.7 6.9 7.7 6.1 9.5 6.7 8.1 10.6 8.5 8.1 7.7 14.6 9.6 10.8 1.4 6.9 3.6 8.1 4.4 3.6 6.1 6.8 7.8 7.3 6.0 7.5 7.2 7.1 7.8 7.6 8.1 7.1 41.4 41.7 17.8 21.9 60.2 37.9 32.1 24.1 14.8 47.6 14.7 15.5 9.1 27.1 16.6 18.4 68.8 11.2 37.7 7.3 3.9 13.1 57.1 8.3 38.5 48.0 18.8 12.0 24.8 10.6 37.0 33.0 20.4 14.1 76.9 26.8 44.3 12.2 12.8 43.7 18.7 6.9 22.4 31.2 91.2 100.6 33.5 24.4 49.8 68.4 32.7 15.9 27.8 37.7 12.6 16.1 4.3 30.9 60.2 34.3 6.6 8.6 10.3 118.8 26.3 27.5 24.0 54.7 39.9 10.6 23.9 9.7 33.5 29.1 12.3 34.1 PRKDC "DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, p350, p460, XRCC7" ENSG00000253729 "Protein kinase, DNA-activated, catalytic subunit" P78527 8 47773111-47960178 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, Ribosome biogenesis" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005167, HPA035174" Supported Enhanced Nucleoplasm NA NA 250000 "Cluster 6: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "CAB005167: AB_2172845, HPA035174: AB_2674504" "unprognostic (3.14e-2)" "unprognostic (3.02e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (8.95e-2)" "unprognostic (1.34e-1)" "unprognostic (7.70e-3)" "unprognostic (5.74e-2)" "unprognostic (1.12e-2)" "unprognostic (1.60e-2)" "unprognostic (7.76e-3)" "unprognostic (7.77e-2)" "unprognostic (2.84e-2)" "unprognostic (2.32e-1)" "unprognostic (2.20e-1)" "unprognostic (6.76e-3)" "unprognostic (2.15e-2)" 17.3 16.8 8.6 14.1 10.7 19.2 16.1 9.8 11.9 18.2 10.8 16.2 7.0 20.1 8.0 24.0 18.3 7.4 16.7 10.6 9.3 14.8 14.0 14.8 17.9 10.4 10.0 19.8 18.0 14.0 16.3 10.9 9.8 13.5 11.6 23.8 16.0 9.2 26.4 19.8 17.2 12.1 10.6 18.8 16.6 18.3 9.6 27.8 13.4 15.0 17.1 18.7 17.5 14.3 123.5 103.4 98.4 93.9 59.9 63.0 41.6 51.2 49.9 70.3 68.9 68.0 39.6 117.1 43.1 63.3 52.3 68.5 131.3 70.2 109.3 26.3 81.8 230.2 92.1 83.7 25.8 88.6 46.0 45.9 22.5 111.3 115.3 27.1 73.4 79.5 156.6 48.0 78.8 57.7 125.8 72.3 108.6 85.6 31.2 60.8 77.3 41.2 35.5 104.4 49.2 62.5 158.1 50.6 51.1 60.2 72.6 60.1 86.2 91.5 78.0 73.0 104.2 41.3 56.7 162.8 51.7 97.9 75.6 11.4 8.1 4.1 8.7 6.8 11.0 13.1 10.8 9.2 6.5 16.7 11.2 10.3 7.7 12.8 13.7 15.3 8.3 2.9 8.6 10.7 9.8 11.9 10.6 9.3 10.4 10.0 9.8 10.6 9.6 14.3 73.4 38.5 36.1 56.8 67.9 38.4 48.3 59.7 77.4 103.4 63.1 64.0 82.1 22.8 44.1 42.3 125.1 61.1 81.9 17.5 17.6 41.9 29.0 66.0 166.5 59.7 25.8 147.6 85.5 36.0 60.6 73.2 55.0 72.6 45.6 105.1 32.5 41.2 35.9 104.3 77.1 31.2 38.7 45.5 20.1 15.5 56.8 54.6 19.6 61.8 63.6 73.1 57.7 82.0 76.0 34.9 16.6 69.6 69.3 57.1 13.2 23.5 50.1 111.6 52.6 91.2 69.3 100.7 106.3 85.3 40.6 33.0 71.0 143.2 55.2 36.4 PRL ENSG00000172179 Prolactin P01236 6 22287244-22302826 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Lactation Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1022 "pituitary gland: 37505.3" "Group enriched" "Detected in some" 5 "Early spermatids: 13.8;Late spermatids: 28.4;Rod photoreceptor cells: 14.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 31.0;SCLC-21H: 8.9;U-937: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB023353, HPA042416, HPA062017" Enhanced "Secreted to blood" NA NA 53900000 7200000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "CAB023353: AB_617369, HPA042416: AB_2677987, HPA062017: AB_2684660" "unprognostic (1.66e-1)" "unprognostic (4.08e-3)" "unprognostic (5.89e-3)" "unprognostic (4.83e-3)" "unprognostic (2.87e-1)" "unprognostic (1.11e-4)" "unprognostic (4.54e-1)" "unprognostic (1.57e-1)" "unprognostic (3.79e-2)" "unprognostic (4.29e-5)" "unprognostic (2.20e-1)" 3.2 11.2 0.3 1.4 0.0 0.0 1.2 0.6 0.1 0.8 0.1 2.7 0.1 11.5 0.0 11.7 1.6 0.1 4.6 0.0 0.2 2.4 9.6 2.1 0.0 0.9 0.7 4.0 5.5 0.0 37505.3 36.6 1.1 2.3 0.0 33.7 3.6 0.0 2.4 7.7 2.5 2.2 0.0 4.0 19.3 4.0 1.0 4.0 14.2 0.0 0.0 0.4 1.6 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.1 0.4 0.0 0.2 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.6 0.1 0.0 0.2 0.9 0.7 1.1 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.0 0.0 13.8 0.1 3.5 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.3 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 2.5 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRLH PRH ENSG00000071677 "Prolactin releasing hormone" P81277 2 237566574-237567175 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "brain: 22.8" "Cell type enhanced" "Detected in single" "Endometrial ciliated cells: 1.0" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.7" "Region enhanced" "Detected in many" "medulla oblongata: 22.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.3;MCF7: 1.8;RPMI-8226: 1.4" "Group enriched" "Detected in some" 58 "hypothalamus: 11.3;pons and medulla: 21.5" "Region enriched" "Detected in single" 14 "medulla oblongata: 5.5" HPA014976 Uncertain "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA014976: AB_2732413" "unprognostic (8.28e-4)" "unprognostic (3.22e-2)" "unprognostic (5.42e-2)" 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 1.2 0.0 0.0 0.1 0.0 22.8 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 8.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.2 22.8 0.1 0.5 5.0 0.9 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRLR ENSG00000113494 "Prolactin receptor" P16471 5 35048756-35230487 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "choroid plexus: 781.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 78.3;Endometrial stromal cells: 113.8;Granulosa cells: 96.4;Proximal tubular cells: 53.0;Syncytiotrophoblasts: 48.3" "Cancer enriched" "Detected in many" 9 "breast cancer: 20.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "T-47d: 382.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (3.81e-2)" "unprognostic (2.41e-1)" "unprognostic (2.37e-2)" "unprognostic (6.04e-2)" "unprognostic (5.05e-2)" "unprognostic (8.21e-2)" "unprognostic (3.99e-2)" "unprognostic (7.94e-2)" "unprognostic (4.89e-2)" "unprognostic (1.67e-3)" "unprognostic (4.84e-4)" "unprognostic (2.50e-3)" "unprognostic (4.15e-3)" "unprognostic (1.89e-1)" "unprognostic (1.12e-1)" "unprognostic (9.84e-5)" "unprognostic (1.24e-1)" 0.6 12.2 9.0 0.5 12.1 1.1 23.1 5.4 3.7 20.8 781.5 5.4 6.6 20.0 9.4 0.7 2.2 0.8 0.2 27.7 24.0 30.7 10.9 0.6 0.1 3.3 5.3 2.3 5.4 82.6 4.3 50.2 2.3 1.1 5.7 0.1 1.7 8.1 0.1 3.1 8.1 10.8 4.2 0.2 6.2 0.6 40.7 0.2 0.1 0.7 0.1 0.8 4.8 0.5 0.0 0.0 0.7 3.1 0.0 2.7 0.6 1.7 1.5 3.2 1.2 0.4 0.2 0.0 0.0 1.9 1.2 0.0 4.3 0.0 3.3 0.7 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 4.5 0.2 0.0 0.0 0.0 0.0 0.2 0.7 10.4 0.3 0.0 0.7 0.8 0.0 0.1 0.0 0.1 0.3 0.7 0.1 0.2 0.0 21.1 0.0 0.7 382.8 3.0 0.0 1.9 2.2 0.6 1.4 0.0 0.0 0.0 3.7 0.2 1.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.0 12.1 5.4 3.7 27.7 24.0 3.3 5.3 2.3 4.2 40.7 0.5 0.2 0.0 2.0 0.7 0.2 2.9 0.3 0.0 3.4 0.0 78.3 31.8 0.8 4.3 0.0 3.7 0.0 32.9 0.5 13.1 7.9 1.3 0.0 7.1 113.8 1.1 8.5 0.0 2.0 5.3 2.4 13.8 11.2 10.5 0.0 96.4 0.7 11.4 8.9 0.0 1.9 16.1 0.0 1.9 0.7 0.2 8.7 3.4 0.0 1.0 7.6 0.0 0.0 0.0 0.6 1.8 15.2 12.8 0.0 1.4 26.4 53.0 0.0 0.0 0.0 0.5 4.6 0.1 0.5 2.2 5.1 48.3 0.7 6.0 23.8 0.1 PRMT3 HRMT1L3 ENSG00000185238 "Protein arginine methyltransferase 3" O60678 11 20387558-20509338 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 54.2;Excitatory neurons: 55.5;Inhibitory neurons: 66.9;Oligodendrocytes: 63.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007832, CAB022083" Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022083: , HPA007832: AB_1855721" "unprognostic (2.08e-2)" "unprognostic (4.43e-2)" "unprognostic (1.08e-2)" "unprognostic (5.98e-2)" "unprognostic (2.57e-2)" "unprognostic (8.97e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (2.01e-1)" "unprognostic (9.92e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (3.17e-5)" "unprognostic (9.15e-2)" "unprognostic (7.22e-2)" "unprognostic (8.86e-2)" "unprognostic (2.09e-1)" "unprognostic (1.40e-2)" "unprognostic (4.11e-2)" 5.0 7.4 4.5 8.1 5.4 8.6 9.6 5.0 8.3 5.1 3.7 6.5 7.6 7.7 3.8 8.2 8.5 5.4 9.7 5.2 5.3 6.9 5.4 4.7 7.8 5.4 5.0 8.1 6.7 11.1 2.6 6.9 5.5 6.1 7.7 7.7 6.5 5.7 10.2 6.2 5.9 7.3 5.0 5.5 6.6 4.3 4.8 9.9 19.8 7.7 8.8 8.0 4.6 7.9 26.5 31.4 18.9 17.4 11.8 19.5 36.1 17.9 15.5 24.5 18.5 25.9 7.2 55.8 12.8 14.1 22.4 34.0 27.2 25.6 37.7 26.1 26.4 26.9 25.5 23.3 24.0 48.8 11.4 16.3 26.3 16.1 54.6 10.3 19.7 19.8 61.1 15.3 15.6 26.7 38.6 16.6 26.7 45.1 27.8 27.9 42.3 46.3 23.8 20.2 18.9 24.8 31.0 28.5 23.2 20.3 30.1 14.1 13.3 19.8 17.3 32.7 34.2 9.1 9.7 58.3 15.7 34.1 39.0 3.8 5.1 4.4 4.4 6.1 7.7 5.3 5.5 4.9 9.8 4.9 6.0 5.2 1.3 10.7 5.2 2.0 3.6 3.9 4.5 5.4 5.0 8.3 5.2 5.3 5.4 5.0 5.5 5.0 4.8 7.9 5.5 9.6 5.1 54.2 11.8 6.0 7.7 6.7 15.9 3.8 6.5 4.2 11.8 4.3 5.7 0.0 2.1 11.4 5.0 3.2 9.8 6.9 3.1 6.0 8.2 5.5 7.8 29.2 55.5 5.1 11.0 8.9 11.2 5.5 5.7 8.0 2.9 4.3 6.5 6.7 66.9 7.3 14.2 5.3 3.6 1.0 6.5 10.9 3.6 35.6 6.7 5.6 2.1 41.7 63.2 5.1 2.2 6.4 8.9 9.5 3.5 5.9 5.8 6.6 0.0 7.8 6.7 13.7 9.6 18.7 5.8 7.3 7.0 12.5 7.6 5.7 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429242 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "liver: 598.5" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 432.9" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 59.7" "Lineage enriched" "Detected in many" 9 "dendritic cells: 59.7" "Cell line enriched" "Detected in some" 16 "Hep G2: 156.1" "Low region specificity" "Detected in all" "HPA005550, CAB016721, CAB016792" Approved "Secreted to blood" NA NA 5200000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.2 0.0 0.6 0.1 1.1 1.1 0.1 0.6 1.0 0.4 0.0 1.0 0.8 0.1 0.1 0.1 0.2 0.6 0.1 0.6 1.0 14.8 598.5 0.2 0.6 1.6 0.8 0.2 0.3 0.0 0.3 0.1 1.5 0.2 0.6 0.2 0.2 0.1 0.2 0.6 0.8 0.0 0.4 0.4 2.6 0.1 0.8 0.6 0.2 0.0 0.3 0.4 0.2 1.1 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.1 0.0 0.9 0.1 0.4 9.5 0.0 0.3 0.0 0.0 0.2 0.1 7.8 156.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.6 0.4 2.3 0.7 0.0 0.1 0.0 0.0 0.9 0.4 0.0 1.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 6.3 0.0 0.0 59.7 0.0 0.3 0.6 1.1 0.6 1.0 0.6 1.0 1.6 0.8 1.5 0.4 0.8 1.1 0.0 0.0 0.0 0.3 4.1 0.8 0.4 11.2 0.0 0.0 0.1 0.0 0.4 47.1 1.2 0.0 0.0 0.0 24.0 3.9 5.9 0.5 0.1 3.4 0.1 0.6 10.3 18.7 0.1 0.2 0.0 0.7 2.0 0.2 0.0 0.0 12.1 432.9 3.7 0.0 0.5 9.3 0.0 9.3 4.0 0.1 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 8.1 0.0 0.0 0.0 3.8 84.8 3.4 0.0 0.0 0.2 0.3 0.1 0.2 0.0 0.1 0.1 1.1 0.0 1.8 0.3 PROK1 "EGVEGF, PK1, PRK1" ENSG00000143125 "Prokineticin 1" P58294 1 110451149-110457358 "Predicted secreted proteins" Angiogenesis "Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "ovary: 197.1;placenta: 50.2;testis: 59.1" "Group enriched" "Detected in some" 8 "Leydig cells: 173.1;Peritubular cells: 668.0" "Cancer enhanced" "Detected in many" "testis cancer: 4.7" "Region enhanced" "Detected in many" "medulla oblongata: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "ASC diff: 22.6" "Region enriched" "Detected in single" 11 "pons and medulla: 1.4" "Low region specificity" "Detected in many" "Secreted to blood" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "unprognostic (2.66e-1)" "unprognostic (2.71e-2)" "unprognostic (1.30e-1)" "unprognostic (1.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.26e-1)" "unprognostic (1.86e-1)" "unprognostic (3.86e-1)" "unprognostic (6.80e-2)" "unprognostic (1.24e-2)" "unprognostic (3.74e-2)" "unprognostic (7.39e-3)" "unprognostic (1.90e-1)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" 4.0 9.8 0.4 0.4 0.3 0.0 5.1 0.4 0.7 14.1 0.2 0.3 0.1 0.3 0.1 1.2 3.5 0.4 2.7 1.1 0.4 0.1 0.2 0.3 0.0 5.5 1.3 197.1 0.3 0.0 0.7 50.2 1.2 12.8 0.0 0.1 0.5 9.9 1.3 2.4 0.2 0.0 1.8 1.5 0.4 59.1 0.9 0.1 0.2 0.0 0.0 4.5 25.1 1.5 0.0 0.0 0.0 0.1 22.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.7 1.1 0.4 5.5 1.3 1.2 1.8 0.9 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.7 0.6 16.4 0.1 0.0 0.0 0.0 0.0 0.1 5.9 0.0 0.3 0.0 1.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 23.4 173.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 668.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.7 1.1 0.0 0.0 1.0 0.1 52.3 0.0 0.1 PROK2 "BV8, KAL4, MIT1, PK2" ENSG00000163421 "Prokineticin 2" Q9HC23 3 71771655-71785206 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biological rhythms" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 64.5;lymphoid tissue: 22.5" "Cell type enhanced" "Detected in some" "Erythroid cells: 5.9;Kupffer cells: 8.0;Macrophages: 11.3;monocytes: 6.9;Spermatocytes: 23.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.1" "Region enriched" "Detected in many" 7 "cerebral cortex: 13.3" "Immune cell enriched" "Detected in many" 50 "neutrophil: 414.4" "Lineage enriched" "Detected in many" 50 "granulocytes: 414.4" "Cell line enhanced" "Detected in some" "HL-60: 9.2;NB-4: 8.9;NTERA-2: 5.5;U-266/70: 12.0;U-266/84: 20.8;U-937: 8.3" "Group enriched" "Detected in some" 6 "basal ganglia: 2.7;hypothalamus: 1.1;olfactory bulb: 3.5" "Low region specificity" "Detected in all" HPA041408 Approved "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA041408: AB_10964057" "unprognostic (5.24e-2)" "unprognostic (3.13e-3)" "unprognostic (3.51e-3)" "unprognostic (3.59e-2)" "unprognostic (1.89e-1)" "unprognostic (2.94e-1)" "unprognostic (2.97e-2)" "unprognostic (9.52e-2)" "unprognostic (4.29e-2)" "unprognostic (9.91e-3)" "unprognostic (6.89e-2)" "unprognostic (5.73e-1)" "unprognostic (1.59e-4)" "unprognostic (2.02e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" 7.2 0.3 0.7 17.7 0.5 64.5 0.3 0.1 13.3 0.4 0.7 0.4 0.3 0.2 0.0 0.4 2.7 1.2 1.0 0.2 0.5 0.6 2.5 13.1 0.2 0.5 1.0 0.2 1.1 0.0 0.4 3.1 1.2 0.2 0.2 0.1 0.3 0.0 0.5 0.1 0.5 1.5 0.2 22.5 0.6 11.4 1.9 1.1 0.5 4.2 0.5 6.0 0.4 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.3 1.6 0.0 0.0 0.0 0.3 8.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 20.8 0.0 0.0 8.3 0.0 0.0 8.2 3.5 3.4 0.7 0.0 0.0 2.7 2.9 0.7 0.0 0.9 5.0 414.4 0.0 0.2 0.3 1.7 3.1 0.7 0.5 0.1 13.3 0.2 0.5 0.5 1.0 1.2 0.2 1.9 0.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 1.8 0.0 0.0 2.5 0.0 0.0 0.0 1.6 0.1 0.1 0.1 0.0 5.9 0.0 0.0 0.0 0.9 0.0 0.0 1.3 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 8.0 0.3 2.8 0.3 11.3 1.8 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 23.8 2.9 0.0 0.0 0.0 3.5 0.1 0.0 0.0 PROM1 "AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4" ENSG00000007062 "Prominin 1" O43490 4 15963076-16084378 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 272.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 581.7;Respiratory ciliated cells: 144.8;Rod photoreceptor cells: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 37.2;CACO-2: 70.6;CAPAN-2: 28.9;EFO-21: 62.2;NTERA-2: 97.4;RPTEC TERT1: 91.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA004922, CAB011525, HPA031053" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB011525: AB_470302, HPA004922: AB_1846238, HPA031053: AB_2673713" "unprognostic (6.33e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-1)" "unprognostic (3.39e-1)" "unprognostic (2.81e-1)" "unprognostic (2.16e-1)" "unprognostic (2.39e-1)" "unprognostic (6.64e-2)" "unprognostic (2.18e-2)" "unprognostic (2.17e-1)" "unprognostic (1.21e-2)" "unprognostic (9.06e-2)" "prognostic favorable (2.56e-5)" "unprognostic (2.16e-2)" "unprognostic (1.02e-1)" "unprognostic (9.38e-2)" "unprognostic (1.17e-1)" 0.3 0.3 4.1 6.2 3.0 4.0 27.7 2.7 3.5 44.9 2.0 30.7 12.4 6.0 4.3 5.1 5.4 30.9 6.7 3.3 2.8 20.9 1.8 3.1 0.0 3.8 4.3 0.1 14.4 0.0 0.1 30.1 3.6 2.8 16.7 272.9 57.9 7.1 1.0 0.9 22.9 3.5 2.8 0.2 24.8 8.0 5.0 0.1 4.8 0.0 0.1 4.2 0.2 3.1 0.0 0.0 37.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 70.6 28.9 0.6 62.2 0.0 0.0 0.1 7.3 0.0 0.1 0.3 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 97.4 0.0 0.0 1.4 0.1 0.0 91.1 0.1 12.0 3.6 0.0 2.4 1.9 3.5 0.6 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 3.0 2.7 3.5 3.3 2.8 3.8 4.3 3.6 2.8 5.0 3.1 0.2 3.2 4.8 1.3 0.3 0.0 0.1 7.2 0.0 14.8 38.2 30.0 8.6 31.5 29.9 82.8 581.7 0.6 1.0 39.3 0.0 64.1 31.4 71.1 1.7 5.1 44.4 2.1 0.9 15.5 0.1 4.4 31.6 14.8 0.0 3.8 0.7 0.1 0.1 10.1 5.4 15.0 34.6 0.0 0.0 44.3 3.1 0.7 0.0 27.2 0.6 47.5 0.0 45.8 1.2 38.2 28.3 6.4 0.4 1.5 18.8 3.6 144.8 311.3 0.0 0.8 3.1 2.1 1.0 0.7 0.0 0.1 0.7 0.3 26.0 4.1 PROS1 PROS ENSG00000184500 "Protein S" P07225 3 93873051-93980003 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 107.5;heart muscle: 116.6;liver: 283.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 83.1;Hepatocytes: 307.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 64.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 112.3;ASC TERT1: 100.1;HSkMC: 78.2;SK-MEL-30: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007724, HPA023974, CAB032610" Approved "Secreted to blood" NA NA 22500000000 5000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "CAB032610: AB_2237647, HPA007724: AB_1079688, HPA023974: AB_1855738" "unprognostic (2.00e-2)" "unprognostic (2.81e-2)" "unprognostic (9.21e-2)" "unprognostic (8.03e-3)" "unprognostic (3.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.48e-2)" "unprognostic (3.07e-1)" "unprognostic (5.18e-2)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.35e-4)" "unprognostic (4.90e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.42e-5)" 33.6 8.7 1.7 8.1 1.3 0.3 24.7 1.6 2.7 14.9 107.5 17.3 13.5 16.4 2.0 16.6 19.4 33.7 116.6 3.2 2.2 37.7 283.1 39.2 4.7 2.1 2.4 32.6 5.6 13.5 8.5 32.0 2.2 8.4 21.6 4.6 12.3 10.3 4.9 20.5 20.6 19.2 1.6 11.2 10.5 5.0 2.3 1.5 17.0 16.9 3.7 18.5 15.1 1.7 0.4 2.7 3.0 27.1 112.3 100.1 1.6 4.6 9.4 1.0 6.6 12.7 1.4 0.0 30.0 3.0 18.8 0.0 1.4 0.9 1.8 0.1 7.3 51.4 1.4 29.8 8.7 1.5 1.2 78.2 0.4 4.0 0.6 63.0 7.2 3.7 32.8 0.1 49.2 0.0 0.1 0.0 3.1 2.7 6.5 0.3 1.2 0.0 27.7 0.0 7.6 19.8 5.0 0.0 157.0 0.6 0.0 19.9 9.4 14.8 2.8 8.2 1.7 0.0 0.0 0.0 60.4 30.4 27.8 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 3.2 1.7 1.3 1.6 2.7 3.2 2.2 2.1 2.4 2.2 1.6 2.3 1.7 55.9 64.1 33.8 17.9 1.9 14.8 3.6 2.1 4.0 0.5 1.7 14.0 44.6 14.3 7.5 1.8 10.4 0.6 0.5 7.5 3.9 9.8 3.2 2.1 30.7 47.1 15.7 16.4 28.4 4.4 0.7 83.1 2.0 1.1 30.9 5.0 65.7 307.1 12.8 1.7 19.7 11.6 0.0 31.5 20.6 6.3 28.6 14.6 19.6 27.2 1.3 22.8 0.0 10.6 4.6 5.6 19.3 36.9 0.3 4.5 1.9 42.2 56.6 8.1 13.1 32.4 28.4 0.4 0.7 11.8 33.2 1.6 2.1 10.8 12.6 2.3 PROZ PZ ENSG00000126231 "Protein Z, vitamin K dependent plasma glycoprotein" P22891 13 113158648-113172386 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 109.2" "Group enriched" "Detected in some" 52 "Hepatocytes: 63.5;Proximal tubular cells: 20.5" "Cancer enriched" "Detected in single" 27 "liver cancer: 12.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.2;Hep G2: 3.6" "Not detected" "Not detected" HPA052006 Supported "Secreted to blood" NA NA 1720000000 650000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA052006: AB_2681691" "unprognostic (5.03e-2)" "unprognostic (4.05e-2)" "unprognostic (1.11e-1)" "unprognostic (2.36e-1)" "unprognostic (6.48e-2)" "unprognostic (1.39e-1)" "prognostic favorable (3.46e-4)" "unprognostic (4.10e-1)" "unprognostic (2.21e-1)" "unprognostic (2.50e-1)" "unprognostic (5.20e-2)" "unprognostic (2.87e-1)" "unprognostic (9.83e-2)" "unprognostic (5.63e-2)" "unprognostic (1.41e-1)" "unprognostic (9.99e-2)" "unprognostic (2.51e-4)" 0.1 0.3 0.1 0.3 0.0 0.1 0.0 0.7 0.2 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 14.4 109.2 0.1 0.3 0.0 0.0 0.1 0.7 0.0 1.2 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.5 0.3 0.0 0.0 0.4 0.5 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.4 0.6 0.3 0.4 0.0 0.0 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.4 1.1 0.4 1.6 3.6 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.3 0.0 0.5 0.3 0.4 0.8 1.4 0.1 0.6 0.1 0.1 0.0 0.5 1.3 0.0 0.0 0.1 0.6 0.7 0.0 0.4 0.3 0.3 0.0 0.3 0.1 0.7 0.4 0.3 0.7 0.4 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 63.5 0.0 0.0 0.1 0.6 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 20.5 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 PRPF8 "hPrp8, Prp8, PRPC8, RP13, SNRNP220" ENSG00000174231 "Pre-mRNA processing factor 8" Q6P2Q9 17 1650629-1684867 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 252.3;Rod photoreceptor cells: 293.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009941, CAB015457" Supported Enhanced Nucleoplasm NA NA 120000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB009941: AB_2171185, CAB015457: AB_831685" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-2)" "unprognostic (3.13e-2)" "unprognostic (1.56e-1)" "unprognostic (4.94e-2)" "unprognostic (6.58e-2)" "unprognostic (1.56e-1)" "unprognostic (4.19e-2)" "unprognostic (1.77e-1)" "unprognostic (2.69e-2)" "unprognostic (1.04e-1)" "unprognostic (2.45e-3)" "unprognostic (2.00e-1)" "unprognostic (2.66e-1)" "unprognostic (1.16e-1)" "unprognostic (1.23e-1)" 78.5 128.7 82.6 45.7 85.0 70.5 78.6 93.2 121.3 98.5 98.7 93.5 33.0 94.5 44.1 85.3 94.2 30.8 100.9 84.4 84.0 78.2 91.2 84.2 52.8 83.6 82.1 131.6 78.3 82.7 130.4 44.7 86.2 89.7 44.5 115.6 78.1 49.1 146.7 92.6 84.2 51.7 80.9 98.2 80.5 100.1 81.5 83.9 89.0 80.1 61.6 96.9 84.3 88.0 104.0 240.7 149.0 116.1 120.8 90.4 107.9 78.2 109.5 160.3 122.4 208.2 50.0 150.0 73.2 150.5 113.4 152.9 356.3 139.5 181.6 99.4 170.0 124.3 187.1 161.0 73.5 145.4 138.9 86.0 91.2 194.8 146.7 84.5 146.1 106.2 121.1 126.6 117.9 112.7 114.4 117.4 97.0 97.7 74.4 218.4 82.3 80.7 63.1 121.1 71.0 103.8 145.0 61.5 69.3 121.6 87.4 91.3 122.1 91.7 78.3 130.2 176.1 46.6 46.7 101.9 81.6 108.1 121.6 23.1 8.9 10.1 19.1 14.4 23.6 17.5 17.7 20.9 15.7 18.3 16.7 20.0 9.0 14.2 21.7 25.2 23.2 11.2 82.6 85.0 93.2 121.3 84.4 84.0 83.6 82.1 86.2 80.9 81.5 88.0 45.7 60.9 84.3 24.5 72.8 30.1 30.0 42.5 56.9 128.0 31.8 34.4 39.4 42.9 53.9 47.8 252.3 43.3 66.6 42.9 7.9 35.5 11.8 45.4 38.8 46.3 36.5 73.0 23.6 40.9 26.7 48.3 56.1 40.3 52.6 55.9 37.9 38.7 39.8 72.3 29.3 40.2 32.6 40.1 26.5 11.2 73.3 42.6 19.6 19.7 48.3 55.9 46.4 21.6 19.0 42.7 36.5 52.3 70.0 31.4 48.7 18.3 51.3 293.2 72.3 65.4 44.8 100.4 99.1 57.3 27.8 39.5 62.8 50.2 50.3 31.5 PRR13 "DKFZP564J157, FLJ23818" ENSG00000205352 "Proline rich 13" Q9NZ81 12 53441678-53446645 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 884.9;Distal tubular cells: 1365.6;Paneth cells: 858.1;Proximal enterocytes: 1642.7;Proximal tubular cells: 1097.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039396, HPA046219" Uncertain Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA039396: AB_2676484, HPA046219: AB_10963936" "unprognostic (1.09e-1)" "prognostic favorable (9.08e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-1)" "unprognostic (8.97e-3)" "unprognostic (4.88e-3)" "unprognostic (1.86e-3)" "unprognostic (7.23e-2)" "unprognostic (1.23e-1)" "unprognostic (3.49e-1)" "unprognostic (1.41e-2)" "unprognostic (5.41e-2)" "unprognostic (6.81e-3)" "unprognostic (1.81e-1)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "prognostic favorable (7.55e-4)" 143.8 207.8 110.8 159.2 110.1 279.1 139.2 112.6 147.7 118.9 109.7 316.1 451.6 104.6 110.8 143.4 139.2 147.1 110.6 105.8 147.8 457.9 192.8 164.3 185.3 126.6 132.1 118.8 133.3 76.0 114.6 95.2 126.3 139.6 265.7 44.0 115.5 86.6 131.6 108.7 432.6 91.4 114.3 230.2 247.8 46.4 118.4 139.0 131.8 59.6 190.4 143.7 111.7 117.1 171.7 339.6 82.6 89.4 135.3 185.3 178.4 142.5 213.0 185.6 179.4 623.1 373.6 265.1 453.5 206.8 225.4 146.6 167.8 225.0 217.9 263.1 124.6 382.4 166.4 294.6 340.7 573.2 489.5 232.6 221.2 326.5 223.6 192.6 195.3 166.1 340.1 254.6 285.1 472.5 325.8 563.8 127.5 229.2 230.7 287.6 67.8 273.9 406.2 283.8 72.3 56.5 202.5 276.7 237.2 169.5 394.0 436.2 196.3 117.2 114.0 201.3 138.0 190.7 241.6 386.4 153.3 345.1 220.2 851.3 824.0 1620.1 511.1 941.9 503.0 888.2 563.7 545.8 649.3 855.6 520.6 557.7 2095.7 584.5 1014.6 539.0 824.8 1573.1 110.8 110.1 112.6 147.7 105.8 147.8 126.6 132.1 126.3 114.3 118.4 117.1 66.8 83.3 110.4 6.8 219.1 47.5 147.8 204.8 82.6 11.1 114.3 95.2 26.4 198.8 145.1 187.6 29.2 225.3 159.1 884.9 1365.6 228.0 12.6 182.7 67.1 80.3 169.8 99.2 6.3 253.9 337.7 76.6 263.0 127.4 186.7 53.4 78.1 152.8 355.2 18.5 7.1 346.9 193.3 345.0 174.4 8.7 58.1 266.8 108.5 9.4 384.7 85.3 297.6 4.5 12.9 332.3 858.1 45.9 120.9 174.7 1642.7 1097.6 215.9 20.9 78.9 33.6 67.1 29.7 22.8 107.1 56.0 291.0 212.7 88.4 340.0 193.1 PRR27 C4orf40 ENSG00000187533 "Proline rich 27" Q6MZM9 4 70133616-70176799 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 959 "salivary gland: 1106.3" "Group enriched" "Detected in some" 25 "Early spermatids: 25.5;Late spermatids: 9.8" "Cancer enriched" "Detected in single" 10 "breast cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036150, HPA036151" Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA036150: AB_10673001, HPA036151: AB_2674971" "unprognostic (9.52e-2)" 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.3 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1106.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PRR29 "C17orf72, DKFZp761M2312, FLJ11724" ENSG00000224383 "Proline rich 29" P0C7W0 17 63998351-64004305 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 58.2" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 57.4;Respiratory ciliated cells: 89.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.5;REH: 3.7;TIME: 2.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051264 Uncertain Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoli "HPA051264: " "unprognostic (2.05e-2)" "unprognostic (6.46e-2)" "unprognostic (2.87e-2)" "unprognostic (2.92e-3)" "unprognostic (4.71e-3)" "unprognostic (3.22e-2)" "unprognostic (3.84e-1)" "unprognostic (3.95e-2)" "unprognostic (1.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.63e-3)" "unprognostic (5.76e-2)" "unprognostic (1.30e-3)" "unprognostic (6.48e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (9.98e-3)" 2.0 0.3 3.2 0.5 2.5 0.3 2.2 1.8 1.2 6.1 12.7 0.4 0.2 0.6 0.3 0.2 58.2 0.7 1.5 4.1 4.2 1.9 0.2 10.4 0.4 12.7 16.0 0.6 0.3 0.9 10.7 0.3 7.3 0.7 0.0 0.0 0.5 0.6 0.6 0.4 0.7 0.2 9.0 5.7 0.3 13.9 4.0 0.2 4.7 0.0 0.3 0.8 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.2 0.0 3.5 0.0 0.3 0.0 0.7 0.0 0.0 0.2 0.1 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 1.0 0.5 0.0 0.0 0.0 1.3 0.0 0.1 0.7 0.1 3.7 0.0 1.5 0.3 0.0 0.2 1.0 0.0 0.1 0.2 0.5 0.5 0.0 2.8 0.1 1.1 0.4 0.1 0.4 0.1 0.2 0.4 0.1 0.0 0.9 0.2 0.0 0.4 0.5 0.1 0.1 0.4 0.2 0.1 0.2 0.7 0.4 0.2 0.2 0.4 0.0 0.2 0.3 3.2 2.5 1.8 1.2 4.1 4.2 12.7 16.0 7.3 9.0 4.0 3.9 3.3 0.0 2.8 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.2 1.5 9.9 3.7 0.0 0.0 0.7 0.0 0.0 0.1 12.4 57.4 0.5 2.1 0.0 0.0 0.5 0.0 0.1 0.6 0.0 1.1 0.0 1.6 1.8 0.5 0.3 0.0 0.4 0.0 0.0 0.0 0.0 10.5 0.0 0.9 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 2.0 0.0 0.0 0.1 89.6 0.0 0.0 0.3 0.3 18.1 1.4 0.0 0.0 0.3 0.7 3.5 0.0 0.1 PRR4 "LPRP, PROL4" ENSG00000111215 "Proline rich 4" Q16378 12 10845849-10849475 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "salivary gland: 6616.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 92.8;Cone photoreceptor cells: 139.7;Horizontal cells: 85.8;Rod photoreceptor cells: 119.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "OE19: 2.8" HPA042133 Supported "Secreted to digestive system" NA NA 14000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA042133: AB_10793979" "unprognostic (1.34e-1)" "unprognostic (2.13e-1)" "unprognostic (1.35e-2)" "unprognostic (1.74e-2)" "unprognostic (1.99e-1)" "unprognostic (5.03e-2)" "unprognostic (3.01e-3)" "unprognostic (3.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.23e-1)" "unprognostic (3.19e-2)" "unprognostic (1.09e-2)" "unprognostic (3.57e-6)" "unprognostic (2.81e-2)" "unprognostic (9.15e-2)" "unprognostic (1.21e-1)" "unprognostic (2.15e-2)" 1.9 2.0 0.6 0.0 0.6 0.1 9.7 0.6 1.8 0.1 0.6 0.2 7.6 0.0 0.0 148.1 0.0 0.0 0.4 0.6 0.6 0.2 0.2 74.4 0.0 0.8 0.6 0.1 2.7 0.0 2.0 0.1 0.6 4.0 0.0 0.0 6616.8 0.1 0.8 73.4 0.2 0.0 0.6 0.1 66.0 0.5 0.6 0.0 0.1 0.0 0.5 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 2.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 1.8 0.6 0.6 0.8 0.6 0.6 0.6 0.6 0.6 0.3 3.2 0.0 0.0 22.0 3.1 6.8 19.9 9.6 92.8 7.5 2.8 1.8 7.2 8.2 1.8 139.7 16.4 20.1 6.3 1.9 0.1 10.2 0.1 0.2 9.6 16.2 14.1 0.0 0.4 2.5 9.3 10.7 0.1 8.9 0.4 14.6 5.9 7.7 85.8 0.0 6.4 24.4 8.7 6.0 13.9 21.8 6.1 28.4 0.0 7.9 18.2 56.7 0.0 0.0 3.4 14.4 24.5 17.1 9.3 7.9 0.2 6.8 119.2 13.1 23.0 7.1 13.5 5.7 8.1 2.3 4.0 20.1 0.5 9.6 4.0 PRR7 MGC10772 ENSG00000131188 "Proline rich 7, synaptic" Q8TB68 5 177446445-177456286 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.7" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 66.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 24.7;SK-MEL-30: 26.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046636 Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA046636: AB_2679730" "unprognostic (3.69e-1)" "unprognostic (9.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (4.08e-2)" "unprognostic (7.94e-3)" "prognostic unfavorable (1.50e-4)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (4.75e-2)" "unprognostic (5.86e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (1.98e-4)" "unprognostic (8.84e-3)" "unprognostic (2.22e-1)" "unprognostic (3.76e-2)" "unprognostic (1.69e-1)" 1.3 4.0 10.7 0.8 11.9 5.8 1.6 1.2 18.7 1.8 6.3 1.3 0.7 2.5 0.0 3.7 4.8 0.1 1.8 17.9 6.7 2.3 2.3 2.0 1.0 2.7 2.1 0.7 2.9 0.4 10.4 0.1 0.7 1.8 0.1 0.3 2.7 0.2 1.2 6.0 1.8 0.1 1.9 3.1 1.3 4.4 7.4 0.5 1.2 0.0 0.5 1.0 2.0 2.8 10.7 4.1 1.1 8.1 0.0 0.6 3.5 4.9 0.9 1.3 1.8 0.9 5.6 10.2 12.6 0.7 4.1 8.8 0.7 4.5 0.5 9.0 12.8 3.1 4.3 3.1 0.9 6.2 7.2 0.9 1.8 0.6 0.3 1.2 0.6 3.9 1.6 7.1 1.3 14.3 5.2 15.8 1.9 1.6 24.7 14.5 3.6 10.5 1.7 0.8 19.8 14.1 1.9 4.8 26.2 0.0 4.3 1.0 3.8 8.0 13.5 7.1 12.0 3.9 2.3 5.1 7.7 9.8 5.9 1.9 0.1 9.7 2.3 0.4 5.5 1.5 2.5 3.9 0.1 2.8 2.4 3.1 3.7 1.7 0.5 2.4 2.0 1.2 10.7 11.9 1.2 18.7 17.9 6.7 2.7 2.1 0.7 1.9 7.4 2.8 11.8 3.2 0.0 4.9 27.9 43.3 28.0 6.8 46.7 13.6 17.2 20.3 1.6 17.2 3.7 7.3 0.0 0.8 55.9 7.4 9.8 10.6 10.6 50.2 12.3 9.2 43.0 3.4 8.6 10.8 0.9 4.8 14.3 22.3 26.7 1.0 4.6 3.1 1.5 6.7 7.0 12.3 16.2 1.9 36.5 13.8 0.9 16.7 28.4 1.0 2.3 19.7 22.6 4.0 5.7 8.6 9.8 2.2 27.3 26.7 11.6 14.2 7.0 16.6 0.0 7.8 8.1 3.3 10.7 33.2 66.9 1.4 37.0 1.5 12.3 17.3 PRRG2 PRGP2 ENSG00000126460 "Proline rich and Gla domain 2" O14669 19 49580646-49591004 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 28.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 47.2;Proximal enterocytes: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 14.9;OE19: 18.0;RT4: 11.7;SK-BR-3: 13.3;T-47d: 14.4;U-266/84: 18.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010702 Approved Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" Cytosol "HPA010702: AB_1079693" "unprognostic (2.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.46e-2)" "unprognostic (1.04e-2)" "unprognostic (1.04e-1)" "unprognostic (7.55e-2)" "unprognostic (5.60e-1)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.67e-1)" "prognostic favorable (3.82e-9)" "unprognostic (4.89e-2)" "unprognostic (1.46e-1)" "unprognostic (6.58e-3)" "unprognostic (3.68e-2)" 1.2 0.4 0.9 1.2 0.9 0.1 7.0 1.3 2.6 4.9 0.6 8.4 12.0 1.5 12.9 13.5 4.9 4.3 1.2 0.9 1.0 11.8 6.4 3.9 0.9 1.2 0.9 0.3 13.1 28.4 15.6 2.1 1.1 6.2 7.7 0.1 11.3 9.0 0.9 12.9 11.0 1.1 0.9 1.0 9.8 0.9 1.1 2.3 13.4 0.1 3.9 6.7 5.5 1.0 11.1 0.4 0.3 0.9 1.3 0.0 4.6 0.2 0.0 0.4 0.4 2.2 14.9 0.7 1.6 0.1 0.3 8.5 0.3 8.5 0.4 1.1 1.2 0.5 0.8 0.7 0.9 0.4 1.1 0.9 7.4 0.3 0.3 0.7 3.4 0.9 0.2 0.8 0.0 2.4 0.2 0.7 0.6 18.0 1.4 0.2 0.3 8.7 6.5 11.7 2.4 0.3 1.3 13.3 0.1 1.0 14.4 0.2 0.6 0.8 0.7 0.4 0.1 5.1 18.7 0.5 0.2 0.3 0.4 0.0 0.2 0.1 0.4 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.2 0.2 0.5 0.0 0.2 1.2 0.2 0.1 0.9 0.9 1.3 2.6 0.9 1.0 1.2 0.9 1.1 0.9 1.1 1.0 6.4 6.4 13.4 0.7 3.4 4.1 11.6 20.2 29.6 2.2 21.5 22.6 0.9 8.6 14.2 12.9 2.1 13.0 4.1 47.2 3.9 31.9 0.7 10.8 4.1 6.4 16.2 1.3 0.5 33.2 6.5 1.6 16.8 16.1 2.5 2.3 1.1 6.8 2.3 5.0 0.4 18.0 8.2 1.9 1.2 0.4 0.3 3.3 1.8 1.9 8.2 0.9 2.1 2.0 0.4 27.4 29.4 0.0 4.4 14.5 46.3 15.5 8.8 4.1 0.0 0.8 3.9 1.9 2.1 23.3 4.7 12.7 4.1 4.6 20.7 14.6 PRRT3 FLJ33674 ENSG00000163704 "Proline rich transmembrane protein 3" Q5FWE3 3 9945542-9952408 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 11.6;fallopian tube: 7.6;parathyroid gland: 15.3;pituitary gland: 11.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 17.2;MCF7: 23.1;SK-BR-3: 33.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035127, HPA035128, HPA069859" Enhanced Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 83000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "HPA035127: AB_10602822, HPA035128: AB_2674482, HPA069859: " "unprognostic (1.55e-1)" "unprognostic (8.41e-2)" "unprognostic (3.42e-1)" "unprognostic (2.38e-3)" "unprognostic (1.27e-1)" "unprognostic (3.41e-2)" "unprognostic (1.15e-4)" "unprognostic (2.27e-3)" "unprognostic (1.37e-2)" "unprognostic (2.76e-2)" "unprognostic (2.20e-3)" "unprognostic (3.60e-1)" "unprognostic (1.01e-4)" "unprognostic (2.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.64e-2)" "unprognostic (2.09e-1)" 0.9 1.8 3.9 1.1 5.0 1.5 1.2 10.1 11.6 1.3 0.3 1.3 0.4 1.2 1.2 1.2 7.6 1.1 1.1 4.4 1.1 1.3 0.4 0.9 1.2 5.1 1.9 1.3 1.8 15.3 11.0 0.3 5.3 2.5 0.3 2.2 2.3 1.7 1.4 2.3 0.9 0.9 0.0 0.9 1.1 2.1 3.6 1.3 2.2 0.2 1.3 1.8 1.1 4.8 0.4 1.0 3.6 4.7 17.2 2.3 1.2 1.8 3.4 2.0 4.5 0.3 3.4 2.0 0.4 4.2 2.1 0.3 1.3 4.5 0.9 9.8 2.0 0.7 1.9 0.2 1.7 0.4 1.7 4.4 0.3 1.7 0.7 9.7 0.8 6.0 1.0 4.7 2.5 23.1 4.4 0.4 8.5 0.1 2.1 2.8 0.4 1.9 1.0 0.4 6.6 4.4 1.8 33.6 0.7 1.4 9.1 0.4 0.7 0.4 4.6 0.9 1.3 6.1 6.6 0.6 10.9 0.3 1.3 0.5 0.2 0.2 1.2 0.1 1.4 0.5 1.3 1.2 0.0 0.6 1.4 1.3 0.3 0.7 0.1 0.6 0.2 0.4 3.9 5.0 10.1 11.6 4.4 1.1 5.1 1.9 5.3 0.0 3.6 4.8 3.3 0.0 2.0 3.9 2.9 2.7 3.8 3.7 3.4 22.8 7.4 6.2 3.0 7.2 3.4 11.0 14.6 0.7 4.4 4.5 3.9 2.9 4.3 5.0 5.4 3.3 11.3 2.1 14.7 5.0 0.5 5.2 5.6 4.9 1.3 7.9 2.2 2.9 3.8 15.2 10.8 5.4 2.0 2.5 2.6 3.5 5.6 2.2 1.8 2.8 11.3 8.6 11.3 5.5 3.7 3.1 1.0 2.6 2.2 4.2 6.4 8.0 12.4 21.6 0.0 7.2 5.3 10.4 6.4 3.4 2.3 0.4 5.6 7.8 4.7 3.0 PRRT4 ENSG00000224940 "Proline rich transmembrane protein 4" C9JH25 7 128350325-128361685 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 16.3;bone marrow: 57.7" "Group enriched" "Detected in some" 7 "Bipolar cells: 4.8;Horizontal cells: 10.1;Inhibitory neurons: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 225.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046373, HPA052681" Uncertain Approved "Nucleoplasm,Peroxisomes,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Peroxisomes, Plasma membrane" "HPA046373: AB_2679642, HPA052681: AB_2681912" "unprognostic (1.72e-1)" "unprognostic (4.55e-2)" "unprognostic (5.36e-3)" "unprognostic (1.20e-4)" "unprognostic (2.60e-1)" "unprognostic (7.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.56e-1)" "unprognostic (5.62e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-4)" "unprognostic (9.11e-2)" "unprognostic (3.73e-4)" "unprognostic (5.28e-3)" "unprognostic (9.09e-2)" "unprognostic (1.22e-2)" "unprognostic (1.27e-2)" 16.3 1.3 3.2 0.4 2.7 57.7 8.5 3.2 2.9 2.5 0.7 1.3 0.1 0.5 0.0 2.7 1.1 0.7 1.5 2.0 6.3 0.1 0.4 0.9 0.1 4.7 4.8 1.1 0.3 0.3 0.2 0.0 4.0 0.4 0.2 1.0 1.1 0.8 4.5 2.3 1.2 0.4 3.6 2.1 2.1 0.4 5.1 0.6 0.5 4.5 0.0 0.5 3.0 2.1 0.0 0.1 0.3 0.5 1.3 0.1 3.8 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.4 0.4 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.2 8.8 0.1 1.3 0.0 0.0 0.1 0.0 0.0 12.8 0.0 0.0 0.0 1.0 2.6 46.6 1.2 0.0 0.1 12.9 0.6 1.0 0.0 0.1 0.5 225.3 0.4 0.2 0.3 1.5 0.1 6.1 0.0 0.0 1.0 0.5 0.1 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.7 3.2 2.9 2.0 6.3 4.7 4.8 4.0 3.6 5.1 2.1 0.4 0.0 0.0 1.0 0.0 0.6 0.1 0.2 0.6 4.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.1 0.2 10.1 12.6 0.0 0.0 0.0 0.7 0.0 0.9 0.1 0.0 0.0 0.1 1.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.3 0.0 0.8 1.2 0.3 0.3 0.1 0.0 0.0 0.1 PRSS1 TRY1 ENSG00000204983 "Serine protease 1" P07477 7 142749468-142753076 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1923 "pancreas: 341429.7" "Cell type enriched" "Detected in some" 28 "Exocrine glandular cells: 57138.3" "Cancer enriched" "Detected in many" 224 "pancreatic cancer: 1920.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "OE19: 10.6;RPMI-8226: 4.5;U-2 OS: 2.8" "CAB025487, CAB025538, HPA062452, HPA063471" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 100000000000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Endoplasmic reticulum" "CAB025487: , CAB025538: , HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.55e-5)" "unprognostic (5.28e-1)" "unprognostic (7.58e-2)" "prognostic unfavorable (6.41e-6)" "unprognostic (8.26e-2)" "prognostic favorable (7.05e-4)" "unprognostic (1.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-1)" "prognostic favorable (4.91e-4)" "unprognostic (3.12e-1)" 45.2 9.9 0.0 4.7 0.0 0.0 25.7 0.0 0.0 19.9 0.0 11.2 54.5 8.9 0.8 15.2 5.6 0.0 51.0 0.0 0.0 9.6 29.7 6.4 6.5 0.0 0.0 177.5 341429.7 0.1 10.3 13.9 0.0 15.2 0.0 0.0 44.2 4.2 8.9 12.1 12.7 0.0 0.0 13.4 77.1 6.9 0.0 0.0 6.4 0.0 0.0 4.7 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 100.7 0.0 0.1 0.0 3.6 0.0 0.0 0.0 57138.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 119.4 0.6 0.0 0.0 0.0 1985.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.2 0.2 PRSS12 "BSSP-3, MRT1" ENSG00000164099 "Serine protease 12" P56730 4 118280038-118353003 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Club cells: 34.3;Cytotrophoblasts: 48.0;Respiratory ciliated cells: 76.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 70.2;SH-SY5Y: 215.4;THP-1: 100.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035054 Uncertain Approved "Nucleoplasm,Actin filaments" "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Actin filaments" Nucleoplasm "HPA035054: AB_10603990" "unprognostic (4.30e-2)" "unprognostic (1.04e-2)" "unprognostic (2.55e-1)" "unprognostic (4.41e-2)" "prognostic favorable (2.66e-4)" "prognostic favorable (1.03e-4)" "unprognostic (4.21e-1)" "unprognostic (3.48e-2)" "unprognostic (7.83e-2)" "unprognostic (6.38e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.29e-1)" "unprognostic (1.85e-1)" "unprognostic (9.55e-2)" "unprognostic (1.09e-1)" 0.6 0.5 1.4 1.6 0.9 0.1 2.2 0.6 1.3 14.5 14.4 6.7 2.7 1.9 0.6 3.2 10.5 9.8 0.0 2.7 0.5 0.8 0.6 7.6 0.1 0.5 1.9 1.6 7.7 0.1 0.6 10.6 0.7 1.4 6.4 0.3 2.5 2.0 0.2 5.9 4.8 1.3 0.5 0.0 9.2 10.0 1.2 1.0 0.2 1.2 5.7 3.8 12.6 0.5 5.2 0.2 1.8 0.0 0.2 13.3 0.1 46.0 41.5 9.7 16.1 0.1 18.7 0.0 0.2 70.2 4.9 0.8 31.1 9.5 12.7 0.2 7.2 0.0 3.6 0.0 1.4 0.0 0.2 4.1 17.5 3.4 9.9 31.2 0.1 0.6 0.0 0.0 8.0 0.3 0.5 9.6 2.2 36.4 2.9 0.0 38.7 0.0 0.0 7.0 5.1 215.4 0.0 0.2 3.0 30.9 0.0 100.6 0.0 19.2 2.8 12.2 9.1 1.0 0.1 0.0 1.0 3.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.6 1.3 2.7 0.5 0.5 1.9 0.7 0.5 1.2 0.5 0.3 6.4 4.6 0.7 0.2 8.4 0.8 16.4 2.2 0.6 0.8 0.8 1.4 10.0 34.3 1.8 0.0 48.0 0.0 26.8 0.0 0.4 9.9 19.7 16.8 0.9 5.3 0.0 10.5 10.2 4.5 7.1 17.9 2.6 7.0 3.3 0.0 0.4 3.8 0.0 14.3 2.7 10.2 0.0 4.2 18.3 0.0 0.4 5.4 7.5 0.0 0.0 0.0 0.5 0.2 8.1 12.8 0.0 0.2 0.4 9.4 0.6 76.1 0.2 0.0 0.6 4.9 10.1 13.3 3.6 4.3 11.9 0.7 21.8 5.3 4.7 PRSS16 TSSP ENSG00000112812 "Serine protease 16" Q9NQE7 6 27247701-27256624 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 58 "lymphoid tissue: 826.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 42.1;Extravillous trophoblasts: 25.4;Syncytiotrophoblasts: 31.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.1" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Cell line enhanced" "Detected in many" "hTCEpi: 20.4;RPMI-8226: 11.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.50e-1)" "unprognostic (6.95e-2)" "unprognostic (1.91e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.74e-2)" "unprognostic (9.21e-3)" "unprognostic (1.57e-1)" "unprognostic (7.89e-2)" "prognostic favorable (6.46e-5)" "unprognostic (1.57e-1)" "unprognostic (3.49e-2)" "unprognostic (5.42e-2)" "unprognostic (1.95e-1)" "unprognostic (5.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.62e-2)" 0.2 0.4 0.0 0.3 0.0 0.0 6.0 0.1 0.3 3.6 0.0 5.7 4.4 0.7 13.5 2.9 5.6 4.0 0.0 0.1 0.0 1.8 0.0 3.8 0.1 0.0 0.0 2.5 14.1 7.8 1.4 4.1 0.1 3.2 6.7 0.1 7.5 4.2 0.0 5.1 3.3 0.2 0.0 0.3 4.8 1.0 0.0 826.7 13.1 0.0 1.4 2.5 1.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.1 3.8 4.7 0.0 0.7 0.0 0.0 1.5 2.7 3.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 2.1 0.5 0.0 20.4 0.0 4.1 0.5 0.0 1.7 2.5 1.9 0.0 1.2 0.5 0.0 0.7 2.1 0.5 0.0 0.0 11.5 2.4 3.6 0.0 0.0 1.4 3.2 0.0 4.5 2.0 0.9 0.0 0.0 0.7 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.7 2.1 0.9 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 9.6 7.7 0.0 2.6 6.4 10.8 4.6 8.6 0.0 16.6 9.5 0.4 15.7 4.6 14.7 0.0 42.1 0.2 22.9 1.9 10.0 0.6 2.5 0.8 0.4 4.2 0.0 0.7 17.6 25.4 0.7 12.8 8.0 5.7 0.1 0.0 0.0 4.0 0.0 0.2 20.0 14.2 0.3 0.4 0.5 0.6 0.3 5.4 0.0 0.2 1.2 0.0 0.0 0.1 9.4 18.7 0.0 13.7 6.9 16.5 0.7 3.4 0.0 0.0 0.0 1.2 2.0 6.1 8.6 6.5 31.7 1.1 0.0 14.9 8.5 PRSS2 TRY2 ENSG00000275896 "Serine protease 2" P07478 7 142760398-142774564 "Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 452 "pancreas: 239420.0" "Cell type enriched" "Detected in some" 11 "Exocrine glandular cells: 108258.7" "Cancer enriched" "Detected in many" 72 "pancreatic cancer: 3463.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "basophil: 4.1;T-reg: 2.9" "Group enriched" "Detected in many" 8 "granulocytes: 4.1;T-cells: 2.9" "Cell line enhanced" "Detected in some" "OE19: 21.0;RPMI-8226: 67.5;U-2 OS: 15.2" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 890000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "prognostic favorable (2.32e-4)" "unprognostic (3.80e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-3)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-3)" "unprognostic (1.48e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-2)" "unprognostic (3.50e-1)" "unprognostic (5.36e-3)" "unprognostic (1.18e-1)" 65.1 12.5 0.1 0.2 0.1 3.2 25.4 0.0 0.1 27.6 0.0 12.6 358.5 11.4 0.0 18.2 9.6 0.1 25.0 0.0 0.0 9.4 32.2 8.2 1.3 0.0 0.0 64.9 239420.0 0.0 13.4 8.1 0.0 17.2 0.0 0.0 25.4 0.9 10.1 11.3 529.2 0.1 0.0 16.9 54.7 8.6 0.0 0.9 8.3 0.0 0.0 7.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.4 4.4 0.5 0.0 0.0 0.0 1.9 0.0 21.0 0.0 0.0 0.0 67.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.9 3.8 0.0 2.9 0.6 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.9 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 378.7 0.0 0.4 0.1 11.4 0.0 0.0 0.0 108258.7 0.0 0.3 4.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 348.9 0.0 0.0 0.0 0.0 9565.7 8.9 0.0 0.1 0.0 60.0 0.1 0.0 0.0 0.0 0.0 36.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 85.4 0.2 PRSS21 "ESP-1, TEST1" ENSG00000007038 "Serine protease 21" Q9Y6M0 16 2817180-2826304 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 84.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 84.1;Early spermatids: 111.0;Late spermatids: 349.7;Spermatocytes: 453.2;Spermatogonia: 270.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 23.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 16.1;eosinophil: 33.0" "Lineage enriched" "Detected in all" 7 "granulocytes: 33.0" "Cell line enhanced" "Detected in some" "CAPAN-2: 25.0;HEL: 28.5;HeLa: 71.0;K-562: 34.3;U-698: 104.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 38 "basal ganglia: 8.9" HPA008477 Enhanced Approved Cytosol "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "HPA008477: AB_1079697" "unprognostic (4.35e-2)" "unprognostic (3.46e-2)" "unprognostic (7.06e-2)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (7.02e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (2.33e-1)" "unprognostic (5.21e-2)" "unprognostic (8.83e-3)" "unprognostic (1.52e-3)" "unprognostic (2.97e-2)" "unprognostic (1.14e-2)" "unprognostic (5.07e-2)" "unprognostic (7.79e-2)" "unprognostic (2.99e-1)" 0.1 0.0 0.1 0.5 0.1 7.8 1.3 0.0 0.1 1.6 0.0 0.7 0.5 0.2 0.0 1.5 2.7 1.8 0.0 0.0 0.1 0.1 0.1 2.5 1.2 0.1 0.0 0.1 2.0 1.5 0.1 0.0 0.1 3.8 0.5 0.0 20.5 0.3 0.0 0.9 0.8 0.1 0.0 1.7 0.8 84.6 0.1 1.1 0.0 0.0 1.2 0.4 1.4 0.1 11.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 25.0 0.0 0.1 0.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 28.5 71.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 13.8 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 104.8 0.0 0.0 0.0 16.1 3.5 33.0 3.1 2.6 4.8 1.2 1.5 2.6 0.9 0.8 2.2 3.2 0.3 1.8 0.5 2.2 1.0 2.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 4.6 1.1 37.9 9.4 13.1 0.0 6.1 8.4 84.1 0.0 2.7 0.0 0.0 0.3 2.1 1.4 0.0 1.1 111.0 0.3 2.6 1.6 0.0 9.7 0.0 0.4 9.0 0.7 0.0 0.4 0.0 0.4 0.0 0.0 11.1 0.0 0.0 1.5 4.1 0.6 0.7 349.7 6.5 5.7 0.0 0.0 1.1 0.0 4.1 0.0 0.1 0.7 0.6 3.8 20.4 32.7 0.1 0.1 0.5 0.0 46.0 0.0 1.0 453.2 270.2 2.8 0.6 0.1 3.4 0.0 2.4 14.5 PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852730-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 79.6;salivary gland: 26.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 221.0;Club cells: 343.9;Ionocytes: 207.5;Pancreatic endocrine cells: 380.6;Urothelial cells: 479.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CAPAN-2: 17.3;MCF7: 14.6;RT4: 10.4;SK-BR-3: 22.9" "Region enhanced" "Detected in some" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA049161: AB_2680660" "unprognostic (1.45e-1)" "unprognostic (9.80e-2)" "unprognostic (3.50e-2)" "unprognostic (4.48e-1)" "unprognostic (2.29e-4)" "unprognostic (2.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (5.06e-1)" "unprognostic (7.52e-2)" "unprognostic (3.74e-3)" "unprognostic (4.12e-1)" "unprognostic (2.32e-4)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 23.4 0.0 0.5 0.3 0.7 0.4 79.6 1.3 0.8 0.0 0.0 0.0 16.7 0.5 2.9 0.0 0.0 0.0 0.0 5.8 1.5 2.4 1.1 0.0 6.0 0.5 0.0 26.9 0.3 0.0 3.2 0.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.3 0.0 2.2 2.5 23.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.3 17.3 0.0 0.0 0.0 0.0 1.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 22.9 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 4.2 0.0 0.2 23.2 221.0 128.8 28.5 0.0 42.8 23.7 0.3 38.6 343.9 16.5 0.0 36.7 1.9 18.5 1.9 113.1 0.0 28.4 4.6 1.8 3.6 0.0 0.0 98.3 37.1 1.3 52.5 56.6 0.0 0.0 0.0 0.1 2.3 0.0 0.0 7.5 207.5 0.0 1.4 0.0 0.0 0.9 7.2 0.0 1.0 0.0 0.0 0.0 0.0 380.6 32.3 0.0 0.3 75.4 0.6 0.2 108.0 0.0 0.0 0.0 13.7 0.1 0.2 22.7 27.6 10.5 2.7 0.0 6.9 479.5 PRSS23 "SIG13, SPUVE" ENSG00000150687 "Serine protease 23" O95084 11 86791059-86952910 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 249.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.1;Endothelial cells: 502.1;Granulosa cells: 347.3;Hepatic stellate cells: 591.8;Theca cells: 445.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 104.6" "Group enriched" "Detected in many" 25 "NK-cells: 34.2;T-cells: 104.6" "Cell line enhanced" "Detected in many" "GAMG: 1093.7;hTERT-RPE1: 1296.9;TIME: 1138.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030591 Uncertain "Secreted to blood" NA NA 440000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA030591: AB_10602067" "unprognostic (2.68e-2)" "unprognostic (1.20e-2)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (2.40e-3)" "prognostic unfavorable (2.12e-4)" "unprognostic (1.89e-2)" "unprognostic (4.30e-2)" "unprognostic (2.08e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (5.56e-4)" "unprognostic (5.35e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.13e-3)" "unprognostic (9.44e-2)" "unprognostic (1.99e-3)" "unprognostic (8.01e-2)" 55.0 21.4 7.8 35.3 7.8 2.1 43.2 7.1 8.7 249.1 12.9 103.6 19.2 103.4 13.4 22.1 24.9 83.8 28.3 7.9 8.0 42.4 15.0 63.3 21.8 14.0 13.9 26.8 29.8 36.0 16.4 61.7 8.8 61.3 50.3 2.7 52.4 128.2 79.6 19.4 29.0 115.5 7.1 18.0 54.2 31.8 14.1 17.5 40.9 18.7 10.2 99.6 79.1 7.4 62.7 153.3 161.1 1.0 70.4 172.3 0.7 269.0 244.4 293.2 232.6 368.1 484.7 0.2 208.2 414.7 1093.7 126.2 2.6 205.0 70.9 0.7 13.0 21.1 74.7 1.4 36.3 0.1 0.9 137.4 26.8 143.2 162.1 1296.9 604.8 0.9 1.3 0.3 223.4 87.7 0.2 0.3 9.8 211.7 16.8 0.0 0.0 0.7 111.5 82.3 1.5 1.0 59.9 4.5 18.7 397.6 6.0 0.6 1138.2 174.0 2.3 351.7 154.5 1.3 1.3 0.8 124.2 0.5 176.3 0.2 0.2 0.1 104.6 0.1 0.2 0.2 17.8 60.0 0.2 0.0 4.7 50.4 1.6 34.2 2.7 0.2 0.0 39.9 7.8 7.8 7.1 8.7 7.9 8.0 14.0 13.9 8.8 7.1 14.1 7.4 95.8 28.9 14.5 14.0 3.2 15.4 96.2 367.1 2.8 1.6 44.7 78.0 4.3 37.1 231.3 53.3 2.1 18.4 53.4 154.8 7.9 162.6 3.1 10.3 130.3 502.1 13.8 20.4 26.3 83.5 15.7 117.1 22.4 7.0 2.5 347.3 591.8 5.2 5.0 0.0 16.5 30.6 85.5 36.6 18.2 6.6 14.3 5.4 72.9 39.4 1.5 0.8 180.2 11.6 2.3 257.7 80.1 7.5 5.8 100.1 5.2 5.7 90.1 0.9 39.5 14.4 105.9 3.0 7.3 1.7 9.8 4.5 24.0 445.1 11.1 60.2 PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712419-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.5;esophagus: 388.6;vagina: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Horizontal cells: 11.8;Squamous epithelial cells: 9.6;Urothelial cells: 11.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.1;SK-BR-3: 24.4;T-47d: 14.6;U-266/70: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" NA NA 8700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB024920: , HPA028848: " "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (3.46e-3)" "unprognostic (5.35e-2)" "unprognostic (5.25e-2)" "unprognostic (2.48e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (4.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.79e-2)" "unprognostic (4.40e-3)" "unprognostic (4.03e-3)" "unprognostic (2.40e-1)" "unprognostic (2.26e-1)" "unprognostic (2.04e-2)" "unprognostic (1.28e-2)" 1.0 0.4 0.9 0.2 0.9 0.3 1.3 1.0 2.0 83.5 0.6 1.0 0.0 1.0 0.0 388.6 0.7 0.2 0.4 0.8 1.4 1.1 0.6 0.6 0.3 1.2 1.5 0.5 0.8 0.7 1.5 0.1 1.0 1.0 0.0 0.2 52.5 0.4 0.3 3.3 0.6 0.0 1.0 0.6 0.8 2.6 1.2 0.6 0.8 0.0 29.9 0.8 134.2 0.9 0.1 0.3 0.4 2.1 0.3 0.7 6.1 0.0 0.2 0.2 0.2 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.5 0.1 0.1 0.0 1.0 0.0 0.3 1.2 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.6 0.0 2.0 0.0 1.1 1.4 0.2 0.0 1.0 0.2 0.1 0.2 0.3 0.7 2.8 0.0 24.4 0.6 0.1 14.6 1.8 0.0 0.4 0.0 0.1 0.0 5.2 3.7 0.5 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.9 1.0 2.0 0.8 1.4 1.2 1.5 1.0 1.0 1.2 0.9 1.5 9.6 5.8 0.0 0.5 1.8 2.5 1.3 0.6 5.2 5.1 6.2 1.2 1.5 5.6 1.8 4.2 0.7 0.5 1.2 0.0 1.5 3.3 0.6 1.4 1.8 0.0 0.0 0.4 1.4 0.6 1.4 1.1 1.6 3.8 1.1 0.4 0.7 0.3 11.8 0.8 0.5 0.0 0.3 3.1 1.0 0.3 0.8 1.8 1.9 0.9 2.6 0.0 0.0 0.3 1.1 1.2 0.0 0.2 1.7 0.1 0.7 3.4 6.6 0.0 2.7 1.5 3.0 3.9 9.6 2.4 3.3 1.3 0.6 1.4 11.1 PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750679-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 268 "pancreas: 31113.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1022.9;Exocrine glandular cells: 2040.4;Pancreatic endocrine cells: 478.8;Paneth cells: 969.9;Proximal enterocytes: 1127.1" "Group enriched" "Detected in many" 7 "colorectal cancer: 72.8;pancreatic cancer: 104.4;stomach cancer: 43.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 104 "basophil: 158.7" "Lineage enriched" "Detected in many" 104 "granulocytes: 158.7" "Group enriched" "Detected in many" 5 "OE19: 316.6;PC-3: 852.5" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 700000000 "Cluster 38: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (3.29e-2)" "unprognostic (5.89e-3)" "unprognostic (1.38e-1)" "unprognostic (2.06e-3)" "unprognostic (1.10e-2)" "unprognostic (8.94e-2)" "unprognostic (7.75e-4)" "unprognostic (5.46e-3)" "unprognostic (2.13e-1)" "unprognostic (8.79e-2)" "unprognostic (4.96e-1)" 3.8 4.6 23.5 7.2 29.3 0.6 1.7 25.8 35.4 30.8 16.9 87.0 92.6 0.4 0.0 116.2 0.3 22.8 6.3 28.2 25.6 3.7 12.4 0.6 0.7 25.0 24.5 12.9 31113.6 0.0 0.7 1.7 25.7 1.1 77.8 0.3 20.9 0.3 0.5 79.7 105.4 3.1 19.4 0.7 22.8 5.1 25.6 0.8 0.4 0.0 15.2 4.2 56.9 24.7 12.0 13.7 0.7 0.0 0.2 5.9 0.1 33.6 7.7 4.1 1.6 34.3 3.0 0.0 0.2 14.9 0.2 15.0 0.0 31.7 10.1 0.4 0.2 0.0 1.1 0.0 2.7 0.0 0.0 0.2 0.0 10.8 110.2 0.3 68.8 0.2 0.0 0.0 0.0 0.2 0.7 0.4 0.2 316.6 852.5 0.0 0.0 0.0 0.0 1.7 0.3 81.2 0.2 0.0 0.0 0.5 0.0 0.0 78.3 0.0 0.0 12.8 0.0 0.0 0.0 0.1 18.1 0.0 0.1 158.7 0.0 0.0 0.2 1.5 1.2 0.0 0.2 0.4 0.5 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.3 23.5 29.3 25.8 35.4 28.2 25.6 25.0 24.5 25.7 19.4 25.6 24.7 0.1 0.0 0.0 0.7 1.9 57.1 0.6 1.3 0.0 0.2 0.1 2.8 1.0 47.1 1.2 1.8 0.0 0.0 0.1 1022.9 3.9 43.2 31.4 0.0 0.0 3.2 192.6 0.0 32.8 2040.4 0.0 0.8 39.3 0.0 8.9 0.0 0.7 4.2 0.0 0.0 4.7 146.4 0.0 0.3 12.1 79.7 1.5 1.2 7.2 3.7 5.7 0.0 0.0 3.5 1.2 478.8 969.9 0.7 0.3 12.1 1127.1 14.7 0.1 0.2 0.0 0.0 1.7 0.5 0.9 1.1 134.1 0.1 2.1 0.0 329.0 56.2 PRSS33 EOS ENSG00000103355 "Serine protease 33" Q8NF86 16 2783953-2787948 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "fallopian tube: 4.7" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Melanocytes: 1.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 8.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 65 "eosinophil: 1296.1" "Lineage enriched" "Detected in many" 391 "granulocytes: 1296.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.7;hTERT-RPE1: 5.0;SK-MEL-30: 5.9;U-2 OS: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (4.78e-1)" "unprognostic (1.22e-1)" "unprognostic (8.99e-2)" "unprognostic (3.38e-2)" "unprognostic (3.10e-1)" "unprognostic (2.86e-2)" "unprognostic (1.16e-1)" "unprognostic (4.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.42e-2)" "unprognostic (2.28e-1)" "unprognostic (1.91e-1)" "unprognostic (2.70e-2)" 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 4.7 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.9 0.4 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.4 1296.1 0.2 0.4 0.2 0.1 0.1 0.0 0.2 0.2 0.1 0.3 2.1 3.3 0.3 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512534-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 50.5" "Cell type enriched" "Detected in some" 36 "Muller glia cells: 410.9" "Group enriched" "Detected in some" 4 "glioma: 2.8;testis cancer: 4.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in single" 195 "T-cells: 19.5" "Cell line enhanced" "Detected in some" "BJ hTERT+: 10.4;CACO-2: 86.3;HAP1: 12.8;RPTEC TERT1: 24.6;SuSa: 17.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.9;cerebellum: 3.6;cerebral cortex: 5.8;hippocampal formation: 5.3;olfactory bulb: 2.7" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "HPA038787: AB_10675951, HPA038788: AB_2676208" "unprognostic (6.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.70e-4)" "unprognostic (6.08e-2)" "unprognostic (1.18e-3)" "unprognostic (2.33e-2)" "unprognostic (7.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.88e-6)" "unprognostic (7.15e-3)" "unprognostic (5.81e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-4)" 1.3 2.4 2.9 0.1 3.8 0.0 0.3 1.7 6.8 2.9 1.5 0.1 0.3 1.3 1.1 0.3 1.4 4.2 4.4 3.2 2.1 3.1 0.4 1.3 0.7 1.8 1.9 10.2 0.3 0.3 1.1 3.6 1.8 1.1 0.3 50.5 0.3 0.4 0.1 0.2 0.1 1.5 1.8 0.7 0.3 3.1 2.6 0.1 0.4 0.1 0.1 1.3 0.5 2.2 0.0 0.5 1.9 0.0 0.1 0.0 0.0 0.3 10.4 1.0 2.0 86.3 0.0 0.0 0.1 0.4 0.0 0.0 12.8 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 3.1 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.6 0.4 8.2 0.0 0.0 0.0 24.6 0.0 0.0 1.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 19.5 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 3.8 1.7 6.8 3.2 2.1 1.8 1.9 1.8 1.8 2.6 2.2 0.3 3.2 0.5 8.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.1 1.5 0.0 0.0 1.8 0.0 0.3 0.0 0.1 9.8 0.1 0.1 0.0 0.3 0.8 1.8 0.0 0.2 0.0 0.0 4.4 0.0 0.0 0.0 0.9 0.0 0.3 0.4 6.7 0.2 0.0 0.0 0.0 0.0 0.2 1.2 0.1 0.0 1.0 0.0 410.9 0.0 1.0 0.1 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 11.4 6.6 0.1 3.7 0.1 0.5 0.0 0.0 0.1 0.7 5.1 0.0 0.0 PRSS36 FLJ90661 ENSG00000178226 "Serine protease 36" Q5K4E3 16 31138926-31150083 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 2.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 11.7;Distal enterocytes: 13.2;Hofbauer cells: 18.7;Paneth cells: 15.4;Proximal enterocytes: 46.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "HeLa: 2.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA036079 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA036079: AB_10602290" "unprognostic (3.74e-2)" "prognostic favorable (2.97e-7)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (4.26e-3)" "unprognostic (1.31e-5)" "unprognostic (4.18e-2)" "unprognostic (5.05e-2)" "unprognostic (2.65e-2)" "unprognostic (8.03e-2)" "unprognostic (2.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (9.86e-2)" "unprognostic (1.23e-1)" "unprognostic (3.13e-1)" 1.4 0.8 0.4 0.3 0.6 0.4 0.5 0.4 0.8 0.2 0.3 0.7 1.0 0.1 0.0 0.3 0.3 0.1 0.3 0.5 0.5 0.2 0.3 0.7 0.1 0.5 0.4 0.1 0.2 0.1 2.6 0.7 0.5 0.1 0.2 0.0 0.5 0.1 0.2 1.0 0.7 0.3 0.4 0.1 0.3 0.4 0.6 0.8 0.3 0.0 0.2 0.4 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.8 2.6 0.4 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 1.0 0.1 0.0 0.2 0.0 0.0 0.4 0.6 0.4 0.8 0.5 0.5 0.5 0.4 0.5 0.4 0.6 0.5 0.3 0.0 1.1 0.7 0.2 1.9 2.6 8.9 1.8 0.5 5.9 11.7 1.1 2.8 3.5 0.0 0.0 0.8 1.2 13.2 0.0 1.7 1.7 0.9 0.6 0.6 0.0 0.4 0.6 2.8 1.2 1.3 1.1 0.9 0.0 0.5 3.3 3.3 18.7 0.0 0.8 4.1 2.0 3.2 3.8 0.9 2.8 4.2 0.0 0.0 5.4 0.6 4.1 0.0 0.1 1.8 15.4 2.6 0.0 1.7 46.9 1.9 1.2 0.0 0.0 0.4 0.4 0.6 4.4 1.5 2.6 0.5 0.5 1.1 3.9 1.9 PRSS37 ENSG00000165076 "Serine protease 37" A4D1T9 7 141836300-141841487 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "testis: 41.3" "Group enriched" "Detected in some" 138 "Early spermatids: 612.8;Late spermatids: 325.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA020541 Enhanced "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA020541: AB_1853004" "unprognostic (4.70e-2)" "unprognostic (5.56e-2)" "unprognostic (2.69e-1)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (1.30e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-2)" "unprognostic (8.30e-7)" "unprognostic (1.42e-1)" "unprognostic (2.06e-1)" "unprognostic (2.72e-2)" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 41.3 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.7 0.2 0.2 0.1 0.3 0.2 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 612.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 325.7 2.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS38 MPN2 ENSG00000185888 "Serine protease 38" A1L453 1 227815693-227846470 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 4.2" "Group enriched" "Detected in some" 17 "Spermatocytes: 28.8;Spermatogonia: 18.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "U-266/84: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (9.54e-3)" "unprognostic (3.61e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS41 TESSP1 ENSG00000215148 "Serine protease 41" Q7RTY9 16 2798470-2805304 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 105 "eosinophil: 10.5" "Lineage enriched" "Detected in single" 105 "granulocytes: 10.5" "Cell line enriched" "Detected in single" 10 "BEWO: 1.8" "Not detected" "Not detected" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "unprognostic (1.58e-1)" "unprognostic (3.65e-1)" "unprognostic (3.04e-3)" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (1.69e-1)" "unprognostic (1.98e-1)" "unprognostic (1.24e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 PRSS48 ESSPL ENSG00000189099 "Serine protease 48" Q7RTY5 4 151277171-151291453 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 18.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 2.2;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 3.7;Sertoli cells: 6.6;Spermatocytes: 3.1;Spermatogonia: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053801 Uncertain "Secreted - unknown location" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA053801: AB_2682267" "unprognostic (9.68e-2)" "unprognostic (1.35e-2)" "unprognostic (2.15e-1)" "unprognostic (2.18e-2)" "unprognostic (3.76e-2)" "unprognostic (4.10e-2)" 0.0 0.0 1.6 0.0 2.2 0.0 0.0 2.8 1.6 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.8 0.0 0.0 0.0 0.0 2.9 1.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.7 1.9 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.2 2.8 1.6 1.0 2.8 2.9 1.0 3.4 0.8 1.9 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.5 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.6 0.1 0.0 3.1 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS50 "CT20, TSP50" ENSG00000283706 "Serine protease 50" Q9UI38 3 46712117-46717869 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pituitary gland: 17.2;testis: 52.0;thyroid gland: 16.5" "Group enriched" "Detected in some" 8 "Spermatocytes: 359.2;Spermatogonia: 303.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HMC-1: 1.4" HPA040768 Supported "Intracellular and membrane" NA NA "Cluster 43: Testis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA040768: AB_2677126" 0.5 1.2 0.9 0.0 0.9 0.1 1.9 2.3 1.5 4.5 0.7 1.6 0.0 1.5 2.9 0.4 2.3 0.1 4.1 1.1 1.2 5.4 2.7 0.7 0.0 1.2 0.9 2.2 4.6 1.4 17.2 0.1 1.0 4.5 0.0 0.2 1.9 2.1 1.2 0.4 0.5 0.2 1.2 0.3 1.0 52.0 1.1 0.2 16.5 0.0 0.0 1.7 2.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 2.3 1.5 1.1 1.2 1.2 0.9 1.0 1.2 1.1 0.9 0.0 0.0 0.0 1.6 0.0 0.1 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 3.1 0.2 0.0 1.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.1 39.5 0.2 0.0 359.2 303.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 PRSS51 ENSG00000253649 "Serine protease 51" A0A1B0GVH4 8 10482878-10547585 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 17 "brain: 22.6" "Group enriched" "Detected in some" 10 "Early spermatids: 3.2;Late spermatids: 3.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 12 "cerebellum: 22.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "unprognostic (2.52e-1)" "unprognostic (3.00e-1)" "unprognostic (3.10e-1)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "unprognostic (2.22e-2)" "unprognostic (2.72e-1)" "unprognostic (7.48e-2)" "unprognostic (1.64e-1)" "unprognostic (7.94e-2)" "unprognostic (1.02e-1)" "unprognostic (6.33e-3)" "unprognostic (2.71e-3)" "unprognostic (7.47e-2)" "unprognostic (3.42e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" 0.0 0.1 0.3 0.1 0.5 0.2 1.1 22.6 1.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.5 0.1 0.0 0.7 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.1 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 22.6 1.9 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS53 POL3S ENSG00000151006 "Serine protease 53" Q2L4Q9 16 31083425-31089628 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.2;liver: 9.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.3;Inhibitory neurons: 4.3;Oligodendrocytes: 4.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 4.8;U-87 MG: 2.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA034955, HPA034956" Uncertain "Secreted in other tissues" NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA034955: AB_2674380, HPA034956: AB_10696365" "unprognostic (3.13e-1)" "unprognostic (4.15e-1)" "unprognostic (3.88e-3)" "unprognostic (1.62e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.63e-2)" "unprognostic (1.04e-2)" "unprognostic (2.87e-2)" "unprognostic (2.72e-2)" "unprognostic (1.63e-4)" "unprognostic (2.53e-12)" "unprognostic (1.02e-1)" "unprognostic (2.01e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" 0.2 0.1 1.7 0.4 1.9 0.0 0.2 1.9 3.2 0.5 1.5 0.4 0.3 0.3 0.1 0.3 0.1 0.3 0.2 1.8 1.9 0.6 9.9 0.4 0.4 1.8 1.8 0.3 0.6 0.0 0.8 0.1 1.8 0.9 0.1 0.1 0.4 0.2 0.1 2.8 0.4 0.4 1.7 0.5 0.5 0.0 1.8 0.1 0.4 0.0 0.0 0.4 0.5 2.2 0.3 0.4 0.1 0.3 0.0 0.5 0.8 0.4 0.8 0.5 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.7 0.8 0.0 0.4 0.3 1.0 0.0 0.4 0.1 0.9 0.2 1.1 0.4 0.0 1.0 1.0 0.0 0.0 0.0 0.0 4.8 0.3 0.4 0.0 0.4 0.0 0.5 0.2 0.3 0.8 0.5 1.6 0.1 0.7 0.2 0.1 2.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.9 1.9 3.2 1.8 1.9 1.8 1.8 1.8 1.7 1.8 2.2 0.2 0.0 0.0 1.6 0.2 0.4 0.2 0.2 0.0 0.4 0.1 0.1 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.3 0.3 0.0 0.4 6.3 0.2 0.2 0.2 1.1 0.3 0.0 0.3 0.4 0.7 0.1 0.0 4.3 0.1 0.0 0.0 0.4 0.2 1.8 0.4 0.0 0.0 0.0 0.1 0.0 0.5 4.4 0.4 0.0 1.2 0.2 0.0 0.7 0.0 0.0 0.4 0.0 0.3 0.2 0.1 0.1 0.5 1.4 0.0 1.0 0.1 0.1 0.3 PRSS54 "CT67, FLJ25339, KLKBL4" ENSG00000103023 "Serine protease 54" Q6PEW0 16 58279997-58295047 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 110 "testis: 41.4" "Group enriched" "Detected in some" 34 "Early spermatids: 526.0;Late spermatids: 208.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA041549 Enhanced "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA041549: AB_10795640" "unprognostic (1.13e-1)" "unprognostic (3.24e-2)" "unprognostic (3.09e-2)" "unprognostic (3.08e-1)" "unprognostic (4.88e-2)" "unprognostic (1.23e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 526.0 0.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 208.3 5.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS55 "CT153, T-SP1, UNQ9391" ENSG00000184647 "Serine protease 55" Q6UWB4 8 10525532-10554166 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 58 "testis: 27.7" "Group enriched" "Detected in some" 46 "Early spermatids: 260.4;Late spermatids: 85.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.64e-1)" "unprognostic (8.44e-3)" "unprognostic (6.10e-2)" "unprognostic (7.40e-2)" "unprognostic (6.23e-5)" "unprognostic (6.62e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 260.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 85.4 1.5 0.3 0.0 0.0 0.0 0.0 0.0 3.0 0.6 0.1 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS56 ENSG00000237412 "Serine protease 56" P0CW18 2 232520388-232525716 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 3.0;retina: 5.3;skeletal muscle: 9.7" "Group enriched" "Detected in some" 10 "Early spermatids: 29.0;Muller glia cells: 45.8" "Group enriched" "Detected in many" 4 "cervical cancer: 1.2;colorectal cancer: 2.5;endometrial cancer: 1.4;melanoma: 2.1;urothelial cancer: 4.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Daudi: 1.0" "Group enriched" "Detected in some" 10 "basal ganglia: 1.8;olfactory bulb: 4.2" "Region enhanced" "Detected in many" "olfactory bulb: 14.9" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (3.26e-1)" "unprognostic (1.98e-2)" "unprognostic (1.31e-1)" "unprognostic (3.73e-3)" "unprognostic (2.28e-1)" "unprognostic (7.15e-2)" "unprognostic (4.64e-2)" "unprognostic (1.20e-1)" 0.0 0.0 0.4 0.0 1.2 0.0 0.0 1.6 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 2.9 1.3 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 5.3 0.0 0.0 9.7 0.0 0.0 0.0 1.1 0.0 0.0 0.8 1.4 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 1.6 3.0 0.1 3.0 2.9 1.3 3.0 1.1 1.4 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 3.6 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS57 "PRSSL1, UNQ782" ENSG00000185198 "Serine protease 57" Q6UWY2 19 685546-695498 "Enzymes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "bone marrow: 165.3" "Cell type enriched" "Detected in some" 9 "Erythroid cells: 77.8" "Cancer enriched" "Detected in single" 10 "pancreatic cancer: 2.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 13 "NB-4: 377.2;THP-1: 184.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (2.89e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" "unprognostic (3.99e-4)" "unprognostic (3.07e-1)" "unprognostic (1.33e-2)" "unprognostic (3.50e-2)" "unprognostic (4.04e-2)" "unprognostic (7.70e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-1)" "unprognostic (3.46e-2)" "unprognostic (8.16e-2)" "unprognostic (2.56e-2)" 0.1 0.0 0.0 0.0 0.0 165.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.1 7.9 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 377.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 184.4 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.0 3.2 0.0 5.9 1.1 0.0 0.4 0.2 0.0 0.0 0.0 3.1 1.5 0.0 0.0 0.5 0.7 2.5 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 77.8 0.1 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.0 0.0 2.5 1.0 8.2 0.0 0.1 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 PRSS58 TRYX3 ENSG00000258223 "Serine protease 58" Q8IYP2 7 142252143-142258058 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 180 "testis: 25.8" "Group enriched" "Detected in some" 129 "Early spermatids: 640.5;Late spermatids: 243.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 640.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 243.0 3.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS8 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 245.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 403.5;Extravillous trophoblasts: 648.4;Paneth cells: 262.6;Proximal enterocytes: 358.0;Syncytiotrophoblasts: 450.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 243.7;CACO-2: 165.9;CAPAN-2: 111.9;hTCEpi: 157.8;OE19: 79.6;SK-BR-3: 186.3" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in single" HPA030436 Uncertain "Secreted - unknown location" NA NA 4400000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favorable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" 0.8 0.4 0.3 15.0 0.4 0.2 25.5 2.1 0.6 31.1 6.7 129.4 155.7 9.9 113.0 136.2 15.4 47.7 0.4 0.6 0.2 90.6 28.0 54.1 0.3 0.3 0.2 0.6 139.4 56.0 8.4 51.0 0.4 49.0 72.6 0.0 245.4 8.5 0.3 115.3 151.8 3.5 0.1 0.2 156.2 0.5 0.2 15.4 50.8 0.0 11.8 4.9 56.0 0.2 63.4 0.2 0.1 0.2 0.0 0.0 243.7 0.0 0.0 0.0 0.0 165.9 111.9 0.0 1.3 0.0 0.0 73.5 0.1 69.7 0.0 0.3 0.4 0.1 0.3 6.5 0.0 0.0 0.3 0.0 157.8 0.0 2.4 0.0 0.0 0.1 1.9 0.1 0.0 68.1 0.6 1.4 20.5 79.6 0.1 0.5 0.0 1.2 7.5 13.1 0.9 0.7 0.0 186.3 0.1 18.8 42.8 0.8 0.0 0.1 1.9 0.6 0.4 0.3 0.5 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.1 0.6 0.6 0.2 0.3 0.2 0.4 0.1 0.2 0.2 0.4 99.3 60.1 0.0 1.0 37.9 82.7 108.9 76.2 0.5 74.4 39.2 0.3 62.9 107.4 42.3 0.0 168.8 0.8 403.5 29.4 192.4 0.0 35.2 11.4 2.6 9.6 2.7 0.1 224.4 648.4 3.5 82.6 109.5 7.0 0.0 0.0 18.2 22.8 0.0 0.2 132.1 87.5 0.3 2.7 0.0 0.6 1.9 3.6 0.0 4.2 0.3 0.0 0.0 0.0 240.7 262.6 0.0 0.1 66.0 358.0 28.6 21.2 0.1 0.0 0.1 4.7 0.0 0.2 81.9 54.0 450.7 2.2 0.0 150.8 91.0 PRTG "FLJ25756, IGDCC5" ENSG00000166450 Protogenin Q2VWP7 15 55611544-55743152 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 10.4;thyroid gland: 10.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 191.8;Oligodendrocyte precursor cells: 51.8;Rod photoreceptor cells: 62.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "AF22: 148.6;SuSa: 172.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA032138 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Vesicles, Plasma membrane" "HPA032138: AB_10669675" "unprognostic (2.80e-1)" "unprognostic (2.42e-2)" "unprognostic (1.32e-1)" "unprognostic (4.64e-2)" "unprognostic (2.07e-2)" "unprognostic (4.96e-4)" "unprognostic (1.82e-4)" "unprognostic (1.31e-1)" "unprognostic (3.19e-1)" "unprognostic (4.76e-3)" "unprognostic (1.37e-1)" "unprognostic (5.32e-2)" "unprognostic (5.67e-2)" "unprognostic (2.42e-6)" "unprognostic (8.81e-2)" "unprognostic (3.17e-2)" "unprognostic (2.70e-1)" 0.5 1.0 1.7 0.4 2.2 0.1 1.1 2.2 1.1 1.2 1.4 0.5 0.1 3.6 0.5 0.1 1.1 0.3 0.6 1.3 2.8 1.5 0.1 1.7 0.1 3.2 2.4 1.9 0.1 1.9 0.9 2.7 3.7 0.4 0.2 10.4 0.2 0.5 0.6 0.1 0.3 1.3 2.9 0.1 0.5 3.6 2.9 0.0 10.7 0.4 0.1 0.4 0.5 5.0 1.2 3.4 148.6 3.2 0.0 0.1 13.2 1.2 4.5 3.9 5.4 25.8 0.8 0.0 5.4 0.2 5.8 0.0 0.6 0.3 5.2 0.0 6.4 1.0 1.1 9.8 1.1 1.0 0.0 0.5 0.2 1.7 2.7 3.0 2.8 0.3 2.7 0.0 2.3 2.2 0.0 0.0 5.9 0.0 3.0 0.0 22.3 0.0 3.1 0.4 1.8 7.6 1.2 1.9 8.3 172.9 0.7 0.5 0.2 2.1 1.6 0.0 4.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 2.2 2.2 1.1 1.3 2.8 3.2 2.4 3.7 2.9 2.9 5.0 3.2 9.6 20.2 17.6 0.0 0.3 0.0 0.0 0.0 12.4 5.0 4.4 6.0 0.0 2.5 16.5 191.8 19.9 0.1 0.1 0.0 0.0 21.8 2.8 25.5 9.7 0.0 0.0 0.7 0.2 4.1 4.0 3.6 3.1 0.0 2.9 3.6 0.0 1.7 0.0 11.1 0.0 0.0 0.0 0.0 25.3 5.3 0.2 0.0 28.1 0.0 4.4 0.0 51.8 13.6 0.4 0.0 2.6 0.1 0.1 0.0 1.4 0.0 62.3 0.0 5.8 2.4 8.9 12.1 0.0 0.0 6.0 0.1 9.5 0.5 0.1 PRTN3 "ACPA, AGP7, C-ANCA, MBT, P29, PR-3" ENSG00000196415 "Proteinase 3" P24158 19 840999-848175 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "bone marrow: 2098.1" "Cell type enriched" "Detected in some" 17 "Erythroid cells: 26.5" "Cancer enhanced" "Detected in single" "stomach cancer: 1.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 8 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.0" "Cell line enriched" "Detected in some" 6 "THP-1: 2054.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005938, CAB017558" Enhanced Approved Vesicles,Cytosol "Secreted to blood" NA NA 390000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Vesicles "CAB017558: AB_2172317, HPA005938: AB_1855764" "unprognostic (2.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.83e-3)" "unprognostic (4.20e-1)" "unprognostic (3.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.98e-3)" "unprognostic (3.67e-2)" "unprognostic (8.62e-6)" "unprognostic (5.31e-2)" "unprognostic (2.00e-1)" "unprognostic (5.14e-2)" 0.8 0.2 0.6 0.0 0.7 2098.1 0.4 0.2 1.3 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.0 1.6 0.6 0.4 0.3 2.8 11.7 0.4 0.3 0.4 0.1 0.1 0.2 1.3 0.6 0.4 0.3 0.0 0.0 1.6 0.0 0.3 1.3 0.0 0.0 0.2 38.2 0.1 0.2 0.6 7.1 0.4 0.0 0.0 0.0 0.1 0.4 1.2 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 343.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 2054.4 0.0 0.0 0.0 0.2 0.9 0.0 0.2 0.3 0.0 14.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 9.9 0.6 0.7 0.2 1.3 0.6 0.4 0.3 0.4 0.4 0.2 0.6 0.4 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.8 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 26.5 0.4 0.0 0.9 0.9 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 1.5 0.0 0.1 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.1 PRX KIAA1620 ENSG00000105227 Periaxin Q9BXM0 19 40393766-40414793 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 34.6" "Cell type enhanced" "Detected in many" "Adipocytes: 17.8;Breast myoepithelial cells: 23.2;Cardiomyocytes: 15.4;Skeletal myocytes: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in some" 8 "spinal cord: 114.2" HPA001868 Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles, Plasma membrane" "HPA001868: AB_2172440" "unprognostic (1.29e-2)" "unprognostic (3.04e-1)" "unprognostic (2.72e-2)" "unprognostic (9.72e-3)" "unprognostic (2.92e-1)" "unprognostic (1.74e-1)" "unprognostic (1.39e-1)" "unprognostic (3.54e-2)" "unprognostic (5.82e-2)" "unprognostic (3.23e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-2)" "unprognostic (2.03e-3)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (9.97e-2)" 4.5 4.7 6.2 1.3 6.8 1.6 3.9 5.2 6.5 4.8 2.9 3.6 1.1 4.4 1.0 2.0 4.2 1.8 3.1 4.7 4.4 6.7 1.0 34.6 1.3 5.4 4.9 6.2 3.8 5.9 1.5 5.1 6.7 4.6 0.7 0.8 3.8 3.5 4.9 3.2 2.2 2.0 4.9 2.0 3.7 1.6 5.7 0.7 9.6 5.5 0.8 4.3 3.1 4.1 1.6 2.6 2.1 2.7 1.3 4.4 2.6 1.4 1.5 1.9 1.4 1.0 1.7 0.5 1.6 1.3 1.2 0.9 1.0 0.6 0.7 0.8 0.9 0.3 0.3 0.5 2.1 0.1 2.3 3.3 3.2 1.2 1.1 1.7 1.6 2.9 2.0 0.5 1.0 2.2 1.0 0.6 0.6 3.8 1.7 3.2 1.8 1.5 0.4 1.8 0.2 1.0 2.7 2.3 2.0 0.9 3.2 1.2 1.4 3.8 2.9 1.6 0.8 5.3 5.0 0.7 1.1 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 6.2 6.8 5.2 6.5 4.7 4.4 5.4 4.9 6.7 4.9 5.7 4.1 17.8 3.2 5.9 0.7 1.4 6.2 2.3 0.3 5.7 0.1 8.1 23.2 15.4 2.8 0.9 1.8 0.0 1.1 1.7 1.0 0.0 0.3 0.1 1.3 1.7 9.2 0.0 0.4 0.6 0.6 0.7 7.0 0.0 3.0 0.0 2.0 6.8 1.3 1.1 0.0 0.5 0.7 2.0 1.6 2.5 0.1 3.4 2.5 3.6 7.5 0.3 3.3 0.0 0.0 0.5 0.5 1.4 4.5 0.9 1.7 1.2 1.9 0.2 0.1 0.0 30.3 6.1 0.3 0.7 5.0 4.1 2.7 1.1 1.3 1.5 1.0 PRY "PRY1, PTPN13LY" ENSG00000169789 "PTPN13 like Y-linked" O14603 Y 22490397-22514637 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059887 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nucleoli" Cytosol "HPA059887: " 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRY2 PTPN13LY2 ENSG00000169807 "PTPN13 like Y-linked 2" O14603 Y 22071756-22096007 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059887 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Nucleoplasm, Nucleoli" Cytosol "HPA059887: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRYP3 ENSG00000169763 "PTPN13 like Y-linked pseudogene 3" O14603 Y 23681440-23694579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 1.7;epididymis: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "A549: 4.5;HDLM-2: 7.7" HPA059887 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 44: HDLM-2 - Immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA059887: " 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.5 0.9 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.7 1.5 0.9 1.2 1.7 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2792.8;Kupffer cells: 2427.0;Macrophages: 1916.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 5104.0;hTERT-RPE1: 6978.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" 1068.6 1192.2 831.4 874.2 946.7 834.2 683.8 873.7 831.7 1073.9 1023.0 667.1 475.6 879.3 951.2 605.5 724.7 1115.6 1413.3 830.5 1081.8 860.4 906.4 1118.6 956.1 957.6 894.0 1106.9 544.7 1167.5 563.5 869.3 885.3 773.9 625.5 665.2 580.9 936.8 1409.5 544.4 487.7 1138.6 1025.9 1045.9 664.0 489.1 1048.8 672.3 875.9 987.5 560.4 941.2 578.3 1325.1 455.9 847.4 540.4 1121.0 5104.0 2910.1 1900.2 799.9 2368.3 620.8 735.9 795.4 1131.9 245.6 1608.1 1321.6 1038.9 964.1 207.5 659.1 434.8 481.4 381.8 288.9 352.3 459.6 1970.7 188.8 1596.0 1871.8 1479.1 625.7 1177.6 6978.9 1128.1 345.8 420.5 1158.1 777.0 294.9 843.8 290.1 249.5 575.4 404.0 172.9 301.3 696.7 730.3 764.4 584.4 515.8 751.1 2248.3 3122.2 700.4 454.4 431.1 1467.0 861.8 610.0 587.1 670.5 1289.0 1038.7 435.4 1375.5 374.4 650.0 863.2 10095.9 1127.5 424.2 11615.6 349.8 466.7 342.9 368.8 3481.1 425.5 370.1 350.6 2890.4 365.8 10148.2 1758.2 422.8 15009.0 831.4 946.7 873.7 831.7 830.5 1081.8 957.6 894.0 885.3 1025.9 1048.8 1325.1 263.2 253.2 339.0 136.8 173.9 228.3 253.4 487.0 108.1 193.8 254.6 158.7 664.1 253.1 318.9 476.3 127.2 891.6 260.2 434.8 70.5 1043.6 19.3 147.0 246.6 311.4 261.9 160.5 86.1 456.1 872.6 623.8 187.6 195.2 398.1 210.8 426.9 509.2 2792.8 333.1 93.7 242.2 343.8 2427.0 779.7 54.1 458.6 1916.9 663.5 105.9 1528.9 495.6 182.3 92.5 117.6 357.7 298.3 551.8 503.0 244.8 370.6 311.6 297.2 164.3 276.1 273.6 263.8 55.2 126.3 137.2 198.0 1073.2 138.9 624.1 228.3 223.9 PSAPL1 ENSG00000178597 "Prosaposin like 1" Q6NUJ1 4 7430285-7434930 "Predicted secreted proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 98.5;stomach 1: 38.6" "Cell type enriched" "Detected in some" 13 "Gastric mucus-secreting cells: 41.8" "Group enriched" "Detected in some" 5 "head and neck cancer: 0.7;melanoma: 2.5;pancreatic cancer: 2.0;stomach cancer: 3.0;urothelial cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CACO-2: 16.6;OE19: 32.2;RPMI-8226: 24.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038013, HPA038482" Approved Enhanced Cytosol "Secreted - unknown location" NA NA 31000 "Cluster 61: Skin - Cornification" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA038013: AB_10673652, HPA038482: AB_2676037" "unprognostic (2.64e-2)" "unprognostic (2.40e-1)" "unprognostic (9.33e-2)" "unprognostic (2.40e-1)" "unprognostic (2.61e-1)" "unprognostic (7.90e-3)" "unprognostic (2.52e-1)" "unprognostic (2.08e-2)" "unprognostic (2.75e-1)" "unprognostic (2.63e-3)" 0.3 0.0 0.0 0.0 0.3 0.0 4.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 98.5 0.0 0.0 0.0 0.0 38.6 3.4 0.1 0.2 0.0 0.0 3.1 0.0 0.2 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.3 0.2 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 PSG1 "CD66f, PBG1, PSBG1, PSGGA" ENSG00000231924 "Pregnancy specific beta-1-glycoprotein 1" P11464 19 42866464-42879822 "CD markers, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 161 "placenta: 259.7" "Cell type enriched" "Detected in some" 98 "Syncytiotrophoblasts: 207.0" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "U-2197: 412.3" HPA046327 Supported "Secreted in female reproductive system" NA NA 75000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (2.02e-1)" "unprognostic (3.54e-1)" "unprognostic (2.44e-7)" "unprognostic (2.28e-2)" 0.0 0.0 0.5 0.0 0.2 0.0 0.0 1.6 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.0 259.7 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.5 0.1 0.6 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 18.1 6.0 1.5 2.3 0.0 0.4 0.0 0.0 21.1 4.3 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.6 0.5 0.0 21.9 0.2 0.0 0.7 0.0 0.0 412.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 1.6 0.9 0.5 0.0 0.2 0.0 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 207.0 0.0 0.0 0.0 0.0 PSG11 "MGC22484, PSG13, PSG14" ENSG00000243130 "Pregnancy specific beta-1-glycoprotein 11" Q9UQ72 19 43007656-43026474 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 87 "placenta: 52.9" "Cell type enriched" "Detected in some" 57 "Syncytiotrophoblasts: 161.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "U-2197: 16.4" "HPA042240, HPA046327" Enhanced "Secreted in female reproductive system" NA NA 40000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA042240: AB_10797384, HPA046327: AB_2679624" "unprognostic (2.58e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.9 0.0 0.1 0.0 0.0 PSG2 "CEA, PSBG2, PSG1, PSGGB" ENSG00000242221 "Pregnancy specific beta-1-glycoprotein 2" P11465 19 43064209-43083045 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 204 "placenta: 238.5" "Cell type enriched" "Detected in some" 30 "Syncytiotrophoblasts: 802.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 10.8;fHDF/TERT166: 23.9;HBF TERT88: 34.8;SuSa: 9.4;U-2197: 45.7" "Secreted in female reproductive system" NA NA 41000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.02e-2)" 0.0 0.0 0.3 0.0 0.2 0.8 0.0 1.1 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 238.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.9 0.3 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 1.8 1.0 4.7 0.0 0.0 0.0 0.0 23.9 1.3 0.5 0.0 0.0 34.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.1 45.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 1.1 0.7 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 2.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 26.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 1.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 802.3 0.0 0.0 0.0 0.8 PSG3 ENSG00000221826 "Pregnancy specific beta-1-glycoprotein 3" Q16557 19 42721638-42740481 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 199 "placenta: 141.5" "Cell type enriched" "Detected in some" 88 "Syncytiotrophoblasts: 1579.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2197: 1.4" HPA046327 Supported "Secreted in female reproductive system" NA NA 67000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 141.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 7.9 0.0 0.0 0.0 3.9 11.2 0.0 0.1 0.3 0.0 0.0 0.4 0.0 17.9 0.9 0.0 0.8 0.0 0.1 0.0 0.0 3.8 0.0 0.4 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1579.6 0.0 0.0 0.0 0.0 PSG4 ENSG00000243137 "Pregnancy specific beta-1-glycoprotein 4" Q00888 19 43192702-43207299 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "parathyroid gland: 55.6;placenta: 143.4" "Cell type enriched" "Detected in some" 38 "Syncytiotrophoblasts: 553.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "fHDF/TERT166: 552.6;U-2197: 147.3" HPA046327 Supported "Secreted in female reproductive system" NA NA 58000000 "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (4.29e-2)" "unprognostic (5.18e-2)" "unprognostic (9.49e-2)" "unprognostic (2.52e-2)" "unprognostic (3.63e-2)" "unprognostic (1.94e-1)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (7.75e-2)" "unprognostic (8.82e-3)" "unprognostic (1.03e-3)" "unprognostic (1.68e-2)" "unprognostic (2.85e-1)" "unprognostic (2.57e-1)" 0.1 0.1 0.1 0.0 0.1 0.0 1.1 0.9 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.5 55.6 0.1 143.4 0.0 0.2 0.0 0.0 1.2 0.2 0.0 3.3 0.0 1.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.8 0.0 1.8 0.1 0.7 0.3 0.0 2.7 0.0 1.9 552.6 4.6 0.0 0.2 0.4 5.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 8.2 53.6 3.6 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.4 0.0 0.0 0.0 7.1 0.9 14.5 0.0 0.0 4.4 2.1 5.5 147.3 0.1 0.2 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.3 0.0 1.5 0.4 0.5 0.3 0.0 0.3 0.0 0.0 4.7 0.0 0.0 0.0 14.3 0.1 0.1 0.2 0.1 0.0 0.0 1.0 0.0 11.9 0.4 0.0 2.7 0.0 0.1 0.0 0.0 2.0 0.0 1.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.5 0.3 0.7 0.0 0.0 0.0 2.7 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 553.7 0.0 0.0 0.0 0.3 PSG5 "FL-NCA-3, PSG" ENSG00000204941 "Pregnancy specific beta-1-glycoprotein 5" Q15238 19 43166256-43186536 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 63 "placenta: 111.8" "Cell type enriched" "Detected in some" 44 "Syncytiotrophoblasts: 724.4" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.5" "Region enhanced" "Detected in single" "cerebellum: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BJ: 427.9;fHDF/TERT166: 1485.4" HPA046327 Supported "Secreted in female reproductive system" NA NA 22000000 "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (1.59e-1)" "unprognostic (3.38e-2)" "unprognostic (4.69e-2)" "unprognostic (1.62e-2)" "unprognostic (2.18e-1)" "unprognostic (2.04e-1)" "unprognostic (1.75e-2)" "unprognostic (1.12e-2)" "unprognostic (2.62e-2)" "unprognostic (1.03e-1)" "unprognostic (7.92e-2)" 0.1 0.0 0.2 0.0 0.2 0.0 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.0 111.8 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.0 0.9 0.1 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.3 0.0 0.0 0.2 0.6 0.1 427.9 122.3 7.0 57.8 0.0 0.3 0.0 0.0 1485.4 1.8 16.4 0.1 0.0 65.8 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.1 0.8 0.0 1.1 7.8 2.3 0.0 0.0 0.0 0.0 0.6 1.6 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 10.2 0.0 0.0 0.1 0.5 1.6 54.9 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.7 0.4 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.3 0.0 1.2 0.0 0.1 0.1 0.0 0.5 1.8 0.0 14.2 0.0 0.1 0.0 6.0 0.8 0.0 0.0 0.2 0.0 0.0 3.3 0.0 16.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 3.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.5 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 724.4 0.0 0.1 0.0 0.1 PSG6 ENSG00000170848 "Pregnancy specific beta-1-glycoprotein 6" Q00889 19 42902086-42919563 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "placenta: 49.4" "Cell type enriched" "Detected in some" 125 "Syncytiotrophoblasts: 363.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "U-2197: 144.6" HPA046327 Supported "Secreted in female reproductive system" NA NA 65000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (4.23e-1)" 0.0 0.0 0.4 0.1 0.2 1.4 0.0 1.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.9 0.5 0.6 1.1 0.0 0.3 0.0 0.0 1.9 0.1 0.2 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.9 0.0 0.0 0.0 0.1 0.3 144.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.2 1.4 0.5 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 363.5 0.0 0.0 0.0 0.0 PSG7 ENSG00000221878 "Pregnancy specific beta-1-glycoprotein 7" Q13046 19 42924132-42937207 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "placenta: 4.1;skin 1: 1.2" "Cell type enriched" "Detected in some" 95 "Syncytiotrophoblasts: 162.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.6;fHDF/TERT166: 1.1;HBF TERT88: 2.3;U-2197: 1.8" HPA046327 Supported "Secreted in female reproductive system" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.1 0.5 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 162.0 0.0 0.0 0.0 0.0 PSG8 ENSG00000124467 "Pregnancy specific beta-1-glycoprotein 8" Q9UQ74 19 42752686-42855691 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "placenta: 6.5" "Cell type enriched" "Detected in some" 11 "Syncytiotrophoblasts: 34.3" "Cancer enriched" "Detected in single" 17 "thyroid cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046327 Supported "Secreted in female reproductive system" NA NA 55000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (1.85e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 3.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.3 0.0 0.0 0.0 0.0 PSG9 "PSG11, PSGII" ENSG00000183668 "Pregnancy specific beta-1-glycoprotein 9" Q00887 19 43211791-43269530 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 135 "placenta: 106.3" "Cell type enriched" "Detected in some" 60 "Syncytiotrophoblasts: 277.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 5.2;GAMG: 16.3;HBF TERT88: 9.3;SuSa: 10.7;U-2197: 9.7" HPA046327 Supported "Secreted in female reproductive system" NA NA 43000000 "Cluster 28: Placenta - Pregnancy" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (9.32e-2)" "unprognostic (3.28e-1)" "unprognostic (2.15e-1)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.5 0.2 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 106.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.7 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 5.2 2.9 4.5 2.3 0.1 0.1 0.0 0.2 1.4 16.3 0.3 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.6 10.7 4.3 0.0 0.2 0.1 2.1 9.7 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 4.3 1.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 4.6 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 277.3 0.0 0.0 0.0 0.0 PSMB6 "DELTA, Y" ENSG00000142507 "Proteasome 20S subunit beta 6" P28072 17 4796144-4798502 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023312, HPA063656" Supported Supported Nucleoplasm,Cytosol NA NA 1400000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA023312: AB_1855828, HPA063656: AB_2685078" "unprognostic (2.71e-1)" "unprognostic (1.86e-2)" "unprognostic (2.75e-1)" "unprognostic (3.32e-3)" "unprognostic (8.80e-2)" "unprognostic (1.44e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (2.37e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-2)" "unprognostic (7.47e-2)" "prognostic unfavorable (5.93e-4)" "unprognostic (1.81e-1)" "unprognostic (2.34e-1)" "unprognostic (5.27e-2)" "unprognostic (5.66e-2)" 92.7 107.8 130.1 82.2 133.7 126.9 107.0 138.1 141.2 92.6 137.4 116.3 76.9 101.9 150.9 140.6 99.2 68.3 201.6 132.8 138.1 134.8 184.6 86.2 90.1 135.7 134.1 63.7 99.3 173.3 82.5 119.8 138.7 84.8 118.3 62.6 100.0 114.2 358.6 114.9 77.0 135.3 136.0 90.4 103.8 76.6 133.5 147.4 88.7 339.5 140.5 110.6 89.2 140.3 279.8 478.2 251.6 216.4 209.9 188.1 289.7 144.1 300.1 431.3 336.0 358.7 220.5 215.0 277.9 348.1 246.5 273.8 388.0 404.4 418.0 281.9 409.7 128.0 315.3 422.7 242.0 133.5 194.4 178.3 305.1 377.4 355.7 241.5 426.5 335.8 199.4 316.6 336.1 331.8 237.4 221.8 214.1 356.2 328.2 261.9 178.7 284.6 326.6 185.3 146.9 179.9 206.6 158.9 148.6 261.4 194.5 147.2 205.1 210.8 158.9 286.4 355.2 130.8 191.8 132.9 301.3 242.1 259.3 410.6 603.3 343.2 347.5 589.9 355.9 668.6 373.1 384.0 624.9 640.8 319.8 329.3 210.5 424.4 549.4 585.5 556.2 817.2 130.1 133.7 138.1 141.2 132.8 138.1 135.7 134.1 138.7 136.0 133.5 140.3 156.3 134.6 113.3 8.5 118.3 229.2 184.1 410.8 112.1 65.5 124.6 153.4 454.8 141.5 253.9 134.3 16.7 587.3 142.8 178.0 358.1 321.6 245.2 110.9 108.1 164.7 148.4 183.7 7.6 349.9 418.2 171.5 105.5 116.0 105.2 156.1 99.6 235.4 346.3 32.0 7.2 173.0 311.3 111.7 272.1 52.9 109.6 159.8 236.5 4.7 298.9 183.4 109.2 9.0 16.9 351.3 163.4 123.0 244.7 191.7 188.6 564.6 193.3 81.3 111.7 119.8 486.8 175.1 84.7 178.6 277.2 664.5 125.9 172.6 177.7 217.3 PSMD8 "HIP6, HYPF, Nin1p, p31, Rpn12, S14" ENSG00000099341 "Proteasome 26S subunit, non-ATPase 8" P48556 19 38374550-38383824 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 708.9" "Cell type enhanced" "Detected in all" "Late spermatids: 1164.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006702, CAB021101" Supported Approved "Nuclear speckles,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Nuclear speckles" "CAB021101: AB_10061018, HPA006702: AB_1079710" "unprognostic (9.50e-2)" "unprognostic (7.02e-2)" "unprognostic (1.70e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.59e-1)" "unprognostic (5.54e-3)" "unprognostic (1.94e-3)" "unprognostic (5.03e-2)" "unprognostic (2.85e-2)" "unprognostic (1.73e-2)" "unprognostic (4.61e-1)" "unprognostic (8.79e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.28e-1)" "unprognostic (2.08e-2)" "unprognostic (2.58e-3)" "unprognostic (4.84e-2)" 224.8 130.8 102.3 78.0 109.6 118.8 184.9 104.1 114.8 109.6 97.6 111.8 98.1 115.8 119.4 156.6 104.0 69.2 361.8 114.4 117.5 122.4 143.0 114.9 90.8 109.2 104.3 82.1 117.3 150.2 111.1 101.1 121.9 107.1 98.9 60.6 118.8 84.5 708.9 178.4 106.4 105.2 105.4 99.4 117.6 145.8 112.6 120.3 91.2 361.1 109.9 106.3 111.0 112.6 337.3 522.7 202.2 231.9 322.0 256.9 105.9 238.7 322.9 358.9 372.3 362.0 196.3 234.7 242.8 320.0 220.1 114.1 341.7 296.8 321.6 389.8 225.6 256.1 159.6 226.4 415.1 260.8 217.9 261.2 290.8 309.7 408.8 197.3 286.5 279.9 324.9 255.7 400.6 332.8 247.6 146.1 157.8 492.8 282.7 254.7 324.6 187.4 255.7 275.1 210.8 214.3 247.3 315.7 233.8 187.1 165.3 242.0 212.7 272.1 251.5 289.0 355.8 257.2 322.4 318.0 410.1 264.8 310.1 169.0 239.5 132.6 188.2 265.1 160.0 172.8 162.0 181.0 263.1 173.6 133.0 129.5 89.0 182.7 319.8 183.2 295.2 352.3 102.3 109.6 104.1 114.8 114.4 117.5 109.2 104.3 121.9 105.4 112.6 112.6 137.4 67.3 67.9 8.1 122.9 206.0 224.5 293.5 80.2 102.6 116.3 141.0 263.8 81.5 158.8 80.9 54.2 367.2 128.2 194.6 348.3 276.0 422.3 137.2 158.2 127.0 146.0 129.2 14.7 267.4 327.5 146.8 71.4 122.5 93.8 146.9 81.4 123.1 296.9 77.4 15.4 183.9 219.7 93.1 169.5 1164.7 118.4 126.9 199.3 10.3 224.0 179.8 143.2 8.0 19.8 296.8 181.2 117.8 178.9 255.0 305.7 332.4 128.5 120.4 151.2 106.6 221.1 305.1 135.4 120.3 212.3 570.3 133.0 201.0 182.5 218.7 PSMF1 PI31 ENSG00000125818 "Proteasome inhibitor subunit 1" Q92530 20 1113240-1189415 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 15 "Early spermatids: 1242.7;Late spermatids: 4603.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041122, HPA041300" Approved Enhanced Cytosol NA NA 160000 "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA041122: AB_10805838, HPA041300: AB_10794370" "unprognostic (1.79e-2)" "unprognostic (8.96e-2)" "unprognostic (7.22e-2)" "unprognostic (3.88e-2)" "unprognostic (1.68e-3)" "unprognostic (1.43e-2)" "unprognostic (9.14e-3)" "unprognostic (1.56e-1)" "unprognostic (7.03e-2)" "unprognostic (4.71e-1)" "unprognostic (2.45e-1)" "unprognostic (7.41e-2)" "unprognostic (3.72e-3)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-2)" "unprognostic (8.32e-2)" 49.7 37.8 32.8 41.8 33.8 53.7 43.4 33.5 35.7 44.3 33.2 46.0 44.2 42.5 27.8 47.7 37.8 26.8 52.0 31.5 33.0 42.4 72.6 43.4 40.9 35.7 33.2 43.8 56.8 43.1 35.2 26.3 34.2 33.3 31.7 32.9 38.8 32.5 128.3 47.2 42.9 36.9 32.8 38.3 44.0 107.6 36.7 41.2 37.7 83.6 39.9 42.3 39.1 35.5 141.5 126.4 29.7 70.3 63.8 66.5 50.8 83.8 64.9 76.1 67.2 118.2 96.4 71.2 56.1 90.3 79.3 123.8 78.9 143.3 95.1 42.3 47.0 99.1 20.8 217.0 83.7 120.6 33.2 67.9 82.3 85.3 132.7 45.9 83.2 55.3 101.5 138.8 62.9 75.4 156.3 107.9 42.6 81.4 79.2 74.5 62.2 118.6 67.7 117.9 75.4 52.4 92.3 159.1 77.3 28.5 108.8 43.3 96.8 95.3 63.8 111.3 115.6 85.9 185.5 77.5 41.8 81.3 74.7 123.8 65.2 123.3 49.8 80.2 57.8 73.2 66.2 54.4 66.3 69.0 59.7 52.8 71.7 58.5 83.0 37.8 81.6 69.4 32.8 33.8 33.5 35.7 31.5 33.0 35.7 33.2 34.2 32.8 36.7 35.5 48.7 35.3 44.2 34.0 58.3 41.2 59.1 81.0 33.0 32.7 40.5 41.5 55.4 31.5 44.8 40.5 4.2 68.0 48.8 51.9 82.2 102.5 1242.7 27.3 38.4 47.4 67.4 190.1 25.2 103.8 88.9 50.2 48.4 28.1 49.5 46.5 50.0 70.0 100.3 21.9 25.4 57.9 34.6 56.3 56.7 4603.4 77.3 58.2 51.6 34.7 76.1 64.3 55.6 22.1 38.1 99.4 75.3 88.8 66.8 69.0 103.3 80.7 32.4 33.1 118.3 36.7 65.0 97.4 90.7 52.1 48.6 74.0 55.0 73.0 62.6 68.8 PSMG4 "C6orf86, PAC4" ENSG00000180822 "Proteasome assembly chaperone 4" Q5JS54 6 3231403-3303373 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067652, HPA074376, HPA075846" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Mitochondria" "HPA067652: AB_2685880, HPA074376: , HPA075846: " "unprognostic (3.13e-3)" "unprognostic (6.00e-2)" "unprognostic (3.60e-1)" "unprognostic (4.11e-2)" "unprognostic (4.11e-1)" "unprognostic (2.20e-1)" "unprognostic (6.52e-3)" "unprognostic (1.57e-2)" "unprognostic (6.96e-2)" "unprognostic (6.74e-3)" "unprognostic (7.40e-3)" "unprognostic (3.02e-2)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.59e-1)" "unprognostic (8.18e-2)" "unprognostic (2.54e-1)" "unprognostic (3.48e-2)" 20.3 18.3 12.8 8.2 15.7 13.8 20.0 19.8 13.7 16.9 5.0 24.1 14.1 18.9 18.6 19.9 18.4 6.9 15.1 11.5 14.6 20.1 26.9 13.7 10.2 17.6 16.0 16.6 33.4 12.0 22.2 7.0 18.1 19.3 6.9 9.9 20.2 13.4 37.1 20.8 16.8 9.5 13.5 14.4 21.4 16.2 15.9 9.3 21.1 11.1 7.7 19.8 16.8 23.8 61.8 29.0 17.5 42.8 15.3 23.1 29.5 27.2 20.0 25.9 41.4 25.1 20.6 21.0 73.1 16.4 20.2 28.9 15.0 18.9 16.9 34.7 65.2 16.9 33.4 66.6 19.2 48.7 16.9 19.8 20.1 18.8 27.8 14.8 32.4 39.9 65.0 15.1 14.0 58.2 27.6 88.9 21.4 31.3 57.7 36.5 9.5 116.2 21.1 24.0 74.3 21.3 12.9 16.7 61.4 16.5 22.0 21.0 31.7 21.4 20.4 24.6 26.6 48.7 76.4 39.4 15.2 34.1 29.3 16.2 35.5 24.4 25.3 36.9 29.4 50.2 42.1 30.8 28.4 52.1 40.9 35.7 8.9 32.3 36.3 33.9 39.4 23.9 12.8 15.7 19.8 13.7 11.5 14.6 17.6 16.0 18.1 13.5 15.9 23.8 45.2 22.4 21.2 18.6 25.3 27.9 29.1 44.2 38.7 32.0 53.1 88.4 21.9 37.1 26.9 44.1 8.4 39.3 15.2 23.6 84.1 43.9 31.4 23.6 25.9 35.2 22.8 18.5 9.6 87.5 37.8 30.4 15.8 17.1 22.2 38.8 28.2 64.5 35.1 25.2 17.8 31.1 28.5 19.2 21.1 13.3 37.0 18.4 30.2 5.6 35.7 22.0 32.0 21.6 15.7 57.8 25.8 23.0 18.9 47.0 47.3 67.2 22.6 29.4 46.0 45.5 54.0 29.6 78.2 39.6 38.2 12.0 23.7 30.0 35.4 27.1 PSORS1C2 "C6orf17, SPR1" ENSG00000204538 "Psoriasis susceptibility 1 candidate 2" Q9UIG4 6 31137534-31139066 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "skin 1: 188.2" "Group enriched" "Detected in some" 8 "Endometrial ciliated cells: 3.3;Glandular and luminal cells: 9.0;Melanocytes: 8.8;Suprabasal keratinocytes: 7.0" "Cancer enhanced" "Detected in many" "testis cancer: 14.6;urothelial cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA061228 Enhanced "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 44: Endometrium - Transcription" "HPA061228: AB_2684455" "unprognostic (8.86e-2)" "unprognostic (7.73e-2)" "unprognostic (1.52e-1)" "unprognostic (5.67e-2)" "unprognostic (5.20e-3)" "unprognostic (1.67e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-2)" "unprognostic (3.78e-1)" "unprognostic (1.64e-2)" "unprognostic (1.06e-1)" "unprognostic (9.40e-5)" "unprognostic (2.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (2.66e-1)" 1.7 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.3 0.0 0.2 0.0 3.5 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 188.2 0.4 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.3 0.0 0.2 0.2 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.8 0.4 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.5 PSPN PSP ENSG00000125650 Persephin O60542 19 6375148-6379058 "Predicted secreted proteins" "Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 4.9" "Cell type enhanced" "Detected in many" "Early spermatids: 8.0;Late spermatids: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" CAB025366 Uncertain "Secreted in other tissues" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" "CAB025366: " "unprognostic (3.21e-1)" "unprognostic (3.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" "unprognostic (3.67e-1)" "unprognostic (2.05e-2)" "unprognostic (5.80e-3)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (6.27e-2)" "unprognostic (1.54e-6)" "unprognostic (5.39e-3)" "unprognostic (1.01e-3)" "unprognostic (4.25e-2)" "unprognostic (2.26e-1)" "unprognostic (2.44e-1)" "unprognostic (1.60e-1)" 0.6 0.8 2.4 0.4 2.6 0.6 0.5 4.9 2.8 1.1 2.0 1.0 0.5 0.9 1.1 1.0 1.1 0.5 0.8 2.6 2.2 1.7 1.5 0.8 0.5 2.2 2.2 1.2 1.1 0.8 1.5 0.4 2.0 1.2 0.5 1.1 0.7 0.5 0.6 0.7 1.1 0.5 1.9 1.2 1.2 1.2 2.3 0.7 1.5 0.4 0.6 0.8 0.8 2.5 0.7 1.6 0.9 2.3 2.1 1.4 0.5 0.8 0.8 0.9 0.9 1.6 0.5 0.8 1.2 1.0 0.8 1.0 1.5 0.6 1.0 1.2 1.2 0.8 0.9 1.2 1.5 0.7 1.2 1.6 1.8 0.7 1.1 2.4 0.6 1.3 1.0 1.0 1.0 1.2 1.6 1.4 0.9 1.6 1.8 1.3 1.1 0.5 1.5 0.9 1.2 1.9 1.3 1.2 1.1 1.1 1.4 0.8 0.7 1.1 1.0 2.0 0.5 1.8 3.1 0.4 2.0 1.4 1.1 1.3 0.5 0.4 0.4 0.4 0.6 0.4 0.3 0.6 0.2 0.5 0.5 0.5 0.8 0.4 0.7 0.6 0.4 0.4 2.4 2.6 4.9 2.8 2.6 2.2 2.2 2.2 2.0 1.9 2.3 2.5 0.8 0.0 1.7 0.0 0.3 0.6 1.0 1.4 0.0 2.5 2.3 1.5 1.8 0.0 0.5 1.8 0.0 1.1 1.0 4.5 0.0 1.2 8.0 2.4 1.7 1.4 3.0 0.8 0.1 0.2 0.7 1.3 0.0 1.9 1.3 2.2 2.2 2.6 2.2 1.7 0.1 2.0 0.0 1.3 0.6 28.7 0.9 0.7 1.8 1.0 1.5 1.8 1.0 0.0 0.0 0.9 4.2 2.2 1.9 1.5 6.2 3.3 2.2 2.2 0.0 1.2 1.3 1.3 0.9 0.9 1.0 1.4 0.7 1.3 2.9 1.1 PSTK "C10orf89, MGC35392" ENSG00000179988 "Phosphoseryl-tRNA kinase" Q8IV42 10 122954381-122997513 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 31.3;Spermatocytes: 37.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037780, HPA037781" Approved Approved "Nucleoli,Nuclear bodies,Actin filaments" No No "Cluster 24: B-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Actin filaments" "Nucleoli, Nuclear bodies" "HPA037780: AB_2675662, HPA037781: AB_10670530" "unprognostic (8.95e-3)" "unprognostic (5.51e-3)" "unprognostic (1.37e-1)" "unprognostic (7.39e-4)" "unprognostic (5.21e-2)" "unprognostic (4.08e-3)" "unprognostic (1.60e-2)" "unprognostic (5.92e-4)" "unprognostic (3.55e-2)" "unprognostic (1.16e-1)" "unprognostic (6.22e-3)" "unprognostic (7.10e-3)" "unprognostic (2.39e-1)" "unprognostic (4.50e-2)" "unprognostic (4.92e-2)" "unprognostic (3.02e-2)" "unprognostic (5.55e-4)" 0.9 2.2 1.3 0.6 1.5 6.1 2.9 1.5 2.2 1.9 0.3 1.6 1.9 1.9 3.5 1.5 1.9 0.7 1.7 1.5 1.6 2.0 4.1 1.0 0.9 1.6 1.5 1.3 2.1 1.1 2.6 1.3 2.5 2.0 1.5 0.5 1.9 1.1 3.5 1.6 1.0 1.9 1.3 1.1 1.3 3.2 1.4 1.8 2.4 0.9 1.2 1.3 1.3 2.8 4.1 3.4 1.7 0.8 1.6 3.2 2.1 2.0 3.5 3.0 3.7 4.6 3.4 4.4 3.9 2.5 2.0 2.3 0.7 3.1 3.4 2.4 8.7 2.7 1.2 4.0 4.3 6.7 3.6 3.3 5.2 2.9 5.2 2.7 2.3 3.9 4.3 6.0 4.3 6.6 2.0 3.9 3.3 1.6 4.3 4.5 3.0 4.4 4.3 2.6 1.6 2.1 3.9 3.8 5.3 1.4 1.8 0.4 3.1 2.8 2.6 1.2 4.5 2.6 1.6 5.8 2.4 4.3 0.9 0.0 5.0 6.0 7.4 3.1 8.8 6.2 5.7 7.0 6.7 5.9 7.5 7.7 0.6 6.8 3.6 6.7 3.8 5.3 1.3 1.5 1.5 2.2 1.5 1.6 1.6 1.5 2.5 1.3 1.4 2.8 3.0 9.6 7.3 14.4 4.6 4.5 5.0 11.0 5.2 8.3 7.1 11.7 5.9 10.0 7.5 5.5 8.4 7.7 8.0 1.6 9.8 4.6 31.3 5.7 5.2 3.2 4.2 3.4 18.8 6.3 3.1 6.0 1.5 11.6 2.5 8.1 3.6 6.3 4.8 5.0 20.3 2.6 14.2 2.1 4.3 5.4 5.3 3.0 5.4 4.7 6.1 8.8 5.2 12.5 29.4 3.7 3.8 5.7 3.3 3.5 3.0 7.7 8.3 11.4 0.0 5.6 8.6 37.5 20.6 5.5 4.7 9.6 6.9 10.8 4.3 3.5 PTCH2 ENSG00000117425 "Patched 2" Q9Y6C5 1 44819844-44843253 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "ovary: 24.6;parathyroid gland: 59.1;salivary gland: 75.2;testis: 25.6" "Cell type enhanced" "Detected in many" "Leydig cells: 107.8;Peritubular cells: 68.1;Plasma cells: 67.1;Theca cells: 138.7" "Cancer enhanced" "Detected in many" "testis cancer: 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/84: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046839 Supported "Nucleoli,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Plasma membrane" Nucleoli "HPA046839: " "unprognostic (6.54e-5)" "unprognostic (1.05e-1)" "unprognostic (7.29e-3)" "unprognostic (3.65e-3)" "unprognostic (3.89e-1)" "unprognostic (7.42e-3)" "unprognostic (3.01e-1)" "unprognostic (2.94e-2)" "unprognostic (1.51e-1)" "unprognostic (8.67e-2)" "prognostic favorable (5.74e-5)" "unprognostic (2.92e-1)" "unprognostic (5.74e-6)" "unprognostic (1.55e-2)" "unprognostic (4.86e-2)" "unprognostic (6.31e-2)" "unprognostic (6.81e-2)" 4.2 3.1 6.1 0.8 3.5 9.4 3.4 6.8 6.8 5.1 3.6 3.6 1.0 6.4 1.6 0.9 4.3 2.5 1.3 3.1 4.4 1.3 1.3 1.0 2.3 2.9 4.8 24.6 1.0 59.1 9.9 0.3 2.0 3.0 0.9 3.6 75.2 1.3 2.0 3.6 1.8 1.2 1.6 2.4 2.0 25.6 6.5 0.8 4.6 0.8 0.7 3.1 3.4 4.8 0.2 0.3 1.0 2.5 0.8 0.9 1.0 0.8 1.6 0.5 0.4 0.2 0.4 1.1 0.4 0.4 0.5 0.0 1.1 0.0 0.2 2.1 1.9 0.6 1.0 0.8 0.3 0.7 1.1 0.3 0.4 1.0 0.1 1.7 0.1 1.0 0.7 1.1 0.0 0.5 1.4 2.1 0.3 0.1 0.4 1.0 0.2 0.5 0.2 0.0 1.5 0.6 0.3 0.4 0.8 0.5 0.2 1.2 0.1 0.2 0.5 1.3 0.5 1.9 11.6 3.2 0.6 3.0 0.4 2.5 1.9 0.1 0.5 0.9 1.0 1.0 0.6 0.6 1.2 1.4 0.7 0.6 0.6 0.9 0.9 3.6 0.3 0.2 6.1 3.5 6.8 6.8 3.1 4.4 2.9 4.8 2.0 1.6 6.5 4.8 2.8 0.0 1.1 14.0 13.4 0.5 0.7 1.0 0.6 0.8 4.8 8.0 1.0 7.2 1.0 1.8 2.1 2.4 6.8 7.8 0.0 5.5 2.3 9.3 13.5 2.7 11.5 1.3 23.7 1.8 1.6 14.3 28.1 8.5 0.0 4.4 0.7 7.9 6.7 8.4 27.3 4.9 2.0 24.5 2.2 8.0 107.8 17.3 0.0 5.6 3.9 2.4 2.1 9.5 2.6 2.1 2.5 68.1 67.1 0.8 13.6 0.2 1.7 1.2 13.1 5.4 5.6 5.0 3.6 0.6 1.6 2.3 7.5 138.7 5.5 0.2 PTGDS "L-PGDS, PGDS" ENSG00000107317 "Prostaglandin D2 synthase" P41222 9 136975092-136981742 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Mast cell degranulation, Prostaglandin biosynthesis, Prostaglandin metabolism, Transport" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 4898.3;testis: 3242.2" "Group enriched" "Detected in many" 11 "Leydig cells: 38051.3;Peritubular cells: 65156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 27 "plasmacytoid DC: 1386.8" "Lineage enriched" "Detected in many" 27 "dendritic cells: 1386.8" "Group enriched" "Detected in some" 6 "HHSteC: 518.7;HSkMC: 252.0" "HPA004938, CAB009916, HPA067456" Uncertain "Secreted to blood" NA NA 2500000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "CAB009916: AB_2174617, HPA004938: AB_1855745, HPA067456: " "unprognostic (2.79e-2)" "unprognostic (3.96e-3)" "unprognostic (9.70e-2)" "unprognostic (5.71e-3)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (2.85e-1)" "unprognostic (2.01e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.19e-7)" "unprognostic (8.49e-3)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (3.21e-2)" 391.1 297.1 1849.2 247.1 2423.8 9.9 121.1 2440.1 2559.6 1675.5 1508.4 84.8 31.5 320.4 735.9 172.5 492.1 396.7 4898.3 1760.9 2034.8 466.5 80.2 607.8 824.1 2339.4 2228.2 66.8 113.2 9.1 398.4 227.8 2318.0 727.0 17.7 146.1 97.8 813.1 108.3 164.9 205.9 99.7 1999.6 317.5 93.0 3242.2 2264.9 127.4 55.1 60.0 306.0 230.3 1181.0 2580.3 0.1 0.0 0.1 0.0 5.4 16.7 8.8 0.3 0.0 0.0 0.0 0.0 0.2 0.6 4.0 24.0 0.0 0.8 0.6 0.2 0.0 0.0 0.0 0.0 1.4 0.3 518.7 0.3 1.3 252.0 0.1 0.0 0.0 1.8 0.0 0.0 0.6 1.0 0.2 0.0 0.0 6.6 0.9 8.2 0.0 0.1 0.2 1.6 0.0 0.0 1.6 2.0 0.0 0.6 0.0 0.1 0.6 68.3 0.7 0.2 0.2 2.1 0.1 0.3 0.0 0.1 3.9 0.0 0.9 0.0 0.3 0.4 50.5 1.0 3.4 0.3 4.3 6.3 1.8 0.2 0.9 9.9 2.3 3.8 0.2 1386.8 1.4 11.2 1849.2 2423.8 2440.1 2559.6 1760.9 2034.8 2339.4 2228.2 2318.0 1999.6 2264.9 2580.3 29.3 0.0 0.6 665.0 1.5 70.4 3.2 0.1 5.7 46.8 6.6 14.7 333.6 8.6 0.1 138.0 52.1 14.4 1863.6 0.2 68.4 0.3 215.9 29.7 1156.5 167.8 0.0 13.5 4.0 0.0 55.0 1584.0 1.1 20.1 1.3 0.3 46.1 1.6 57.3 21.9 12.8 0.0 0.0 3.4 161.8 1230.9 38051.3 57.0 209.9 176.1 4.6 4625.8 583.9 63.3 850.4 1.7 0.0 65156.8 6.0 20.7 0.0 1.1 0.0 130.3 164.3 787.4 124.8 130.7 111.1 12.0 80.1 35.4 61.3 0.1 0.0 14.5 PTGIR IP ENSG00000160013 "Prostaglandin I2 receptor" P43119 19 46620468-46625089 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 55.5" "Group enriched" "Detected in some" 5 "Langerhans cells: 177.2;monocytes: 160.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "classical monocyte: 28.2;intermediate monocyte: 65.3;myeloid DC: 20.9;non-classical monocyte: 38.7" "Group enriched" "Detected in many" 11 "dendritic cells: 20.9;monocytes: 65.3" "Cell line enhanced" "Detected in some" "BJ: 10.8;BJ hTERT+: 12.2;fHDF/TERT166: 15.4;HDLM-2: 7.6;HEL: 28.3;HHSteC: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 3: Monocytes - Immune response regulation" "unprognostic (3.79e-1)" "unprognostic (1.95e-1)" "unprognostic (2.94e-2)" "unprognostic (2.39e-1)" "unprognostic (1.03e-1)" "unprognostic (3.49e-3)" "unprognostic (4.22e-2)" "unprognostic (6.09e-2)" "unprognostic (2.12e-1)" "unprognostic (7.45e-2)" "unprognostic (4.47e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.09e-8)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.74e-4)" "unprognostic (1.16e-1)" "unprognostic (5.66e-2)" 13.7 6.8 0.5 6.0 0.4 3.4 5.2 0.4 0.9 6.0 0.4 4.8 2.0 4.6 0.3 2.1 4.5 2.9 27.3 0.6 0.4 26.1 9.2 55.5 3.5 0.6 0.5 2.4 5.7 0.6 1.9 4.4 0.5 2.6 1.0 0.0 4.1 0.9 2.8 4.3 5.8 2.9 0.6 10.8 6.7 0.3 0.5 1.5 16.6 0.8 2.6 6.0 5.2 0.5 0.0 0.0 0.0 0.0 0.2 5.5 0.0 10.8 12.2 1.5 4.3 0.0 0.0 0.0 0.9 15.4 0.1 0.0 0.0 0.0 0.9 7.6 0.0 28.3 0.0 0.0 7.2 0.0 0.0 1.7 0.0 3.9 0.2 0.0 3.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.5 1.4 1.7 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.7 0.7 0.0 28.2 0.0 0.0 65.3 0.4 1.5 0.3 0.0 20.9 0.7 3.3 0.1 1.1 0.0 38.7 2.0 3.9 17.6 0.5 0.4 0.4 0.9 0.6 0.4 0.6 0.5 0.5 0.6 0.5 0.5 1.5 0.0 0.6 0.3 3.7 4.2 0.8 0.4 0.0 0.4 0.2 0.5 0.9 0.0 0.1 1.8 0.0 0.1 2.7 0.2 0.0 0.3 0.2 0.1 1.5 2.3 0.0 0.4 0.7 0.4 0.1 10.3 0.5 0.1 3.8 0.1 4.2 0.2 2.6 0.0 0.6 0.0 0.0 7.9 177.2 0.0 2.1 23.7 7.2 0.0 160.9 0.1 1.0 0.5 0.3 0.4 0.0 0.0 0.1 0.8 0.0 0.2 0.7 0.8 6.6 1.1 30.9 0.1 0.4 0.0 4.4 0.3 2.0 0.1 0.0 0.7 PTGS1 "COX1, PGHS-1, PTGHS" ENSG00000095303 "Prostaglandin-endoperoxide synthase 1" P23219 9 122370530-122395703 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 108.3;skin 1: 152.5;urinary bladder: 175.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.9;Glandular and luminal cells: 191.9;granulocytes: 208.0;Hepatic stellate cells: 61.8;Macrophages: 55.3;Suprabasal keratinocytes: 58.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 28.9" "Group enriched" "Detected in many" 6 "dendritic cells: 20.0;granulocytes: 28.9;monocytes: 13.1" "Cell line enhanced" "Detected in many" "ASC diff: 113.7;ASC TERT1: 89.5;BJ: 115.2;BJ hTERT+: 156.0;HEL: 73.6;HMC-1: 298.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002834, CAB020315" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "CAB020315: , HPA002834: AB_1079711" "unprognostic (4.20e-1)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.27e-2)" "unprognostic (5.88e-2)" "unprognostic (2.00e-2)" "unprognostic (1.22e-3)" "unprognostic (3.32e-1)" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (4.03e-2)" "unprognostic (1.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.35e-4)" 12.8 2.9 3.1 10.5 3.2 9.0 6.7 4.2 4.8 5.8 5.5 108.3 10.8 6.1 2.2 67.3 43.2 9.6 12.6 7.4 5.5 9.3 3.0 11.3 4.6 6.5 5.2 2.0 1.8 2.0 4.8 2.2 6.3 21.1 24.2 0.7 4.3 6.1 2.1 152.5 17.7 16.1 6.7 8.0 20.5 0.9 7.0 2.2 3.2 4.0 11.6 175.0 15.9 11.9 0.3 0.5 0.4 0.0 113.7 89.5 0.0 115.2 156.0 1.0 1.1 0.0 0.2 4.2 5.4 19.7 0.3 7.1 0.4 10.5 0.9 0.0 0.2 73.6 0.6 0.0 32.9 5.2 298.4 46.1 1.2 5.7 0.3 0.0 42.3 0.1 0.1 0.3 2.3 0.0 0.2 6.6 1.6 0.0 0.5 0.3 1.4 8.6 14.7 0.0 0.5 0.6 0.6 9.5 0.2 0.5 0.3 8.4 1.0 0.7 0.6 1.7 0.1 0.3 0.2 0.0 0.4 31.6 0.3 28.9 12.1 23.3 0.0 13.1 0.0 2.4 0.0 0.0 20.0 3.5 0.1 0.0 5.2 2.8 10.2 1.4 0.2 21.9 3.1 3.2 4.2 4.8 7.4 5.5 6.5 5.2 6.3 6.7 7.0 11.9 0.9 0.0 6.6 0.0 5.9 9.9 2.6 7.7 0.0 0.1 1.1 1.4 1.6 4.3 2.2 42.3 0.0 0.1 0.2 0.1 0.0 0.6 0.1 109.9 10.4 24.7 1.8 18.7 0.8 0.5 0.3 10.7 2.0 191.9 208.0 0.1 61.8 0.8 26.1 0.0 0.5 0.6 4.1 15.5 20.7 0.3 1.5 55.3 3.6 16.9 11.7 0.0 7.2 1.0 0.1 0.6 0.6 0.0 0.3 2.8 0.0 0.0 0.8 0.1 0.0 1.4 3.6 0.0 0.2 18.2 58.7 0.4 3.4 0.1 1.0 0.8 PTGS2 COX2 ENSG00000073756 "Prostaglandin-endoperoxide synthase 2" P35354 1 186671791-186680922 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 116.7;seminal vesicle: 127.4;urinary bladder: 162.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 342.9;Fibroblasts: 270.7;granulocytes: 347.6;Langerhans cells: 305.6;Macrophages: 173.1;Urothelial cells: 151.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "neutrophil: 11.7" "Lineage enriched" "Detected in single" 16 "granulocytes: 11.7" "Cell line enriched" "Detected in many" 4 "BJ hTERT+: 405.5" "Region enhanced" "Detected in many" "hippocampal formation: 15.1" "Low region specificity" "Detected in many" "CAB000113, HPA001335" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "CAB000113: , HPA001335: AB_1079712" "unprognostic (1.36e-3)" "unprognostic (9.97e-3)" "unprognostic (3.97e-2)" "unprognostic (3.31e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (5.96e-2)" "unprognostic (9.50e-2)" "unprognostic (9.03e-3)" "unprognostic (2.81e-1)" "unprognostic (3.24e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (8.04e-3)" "unprognostic (4.38e-2)" "unprognostic (8.89e-2)" "unprognostic (3.74e-2)" 17.0 7.9 1.4 13.9 2.5 116.7 3.0 1.1 4.1 62.2 2.7 14.9 2.6 8.9 0.7 6.9 5.1 31.6 11.7 1.9 1.4 10.2 8.0 34.3 8.9 2.0 1.6 2.6 2.2 5.6 3.1 8.4 1.5 25.0 9.9 0.3 1.2 127.4 0.4 1.6 3.6 12.2 1.9 2.8 14.8 0.2 1.8 5.2 3.2 6.5 0.6 162.5 2.2 2.6 0.0 21.8 0.1 0.0 2.5 2.1 0.0 93.4 405.5 0.6 3.6 15.0 17.2 0.0 0.0 0.1 2.5 12.2 0.0 7.6 1.3 0.0 0.0 0.8 2.2 0.0 13.2 0.0 0.2 0.8 2.7 11.3 28.7 1.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 5.5 1.5 0.0 1.0 0.0 0.9 2.7 0.0 0.1 1.5 19.3 0.6 13.5 0.6 0.2 0.0 0.0 27.7 0.4 2.3 0.0 0.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 11.7 0.0 0.4 0.0 0.0 0.0 1.4 2.5 1.1 4.1 1.9 1.4 2.0 1.6 1.5 1.9 1.8 2.6 5.2 342.9 77.7 0.0 7.4 118.8 59.1 72.8 12.5 0.0 2.6 12.8 2.5 0.0 79.7 0.0 0.0 0.2 4.2 0.3 0.0 0.8 0.2 50.0 9.9 31.1 1.2 3.6 3.8 0.2 0.3 270.7 2.0 98.9 347.6 3.8 13.6 0.2 12.1 0.0 1.0 1.0 8.2 21.0 305.6 0.0 0.0 173.1 35.6 3.7 3.4 0.1 0.0 0.0 0.1 4.9 0.1 0.0 2.0 122.6 0.2 0.3 13.1 0.3 0.0 1.8 12.8 0.1 0.4 3.3 28.4 0.5 10.8 3.7 1.2 151.6 PTH PTH1 ENSG00000152266 "Parathyroid hormone" P01270 11 13492054-13496181 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 245 "parathyroid gland: 50184.7" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 1.0;Oligodendrocyte precursor cells: 1.0;Oligodendrocytes: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000072, CAB023409, CAB026363, HPA048540" Enhanced "Secreted to blood" NA NA 28000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB000072: , CAB023409: AB_619175, CAB026363: , HPA048540: AB_2680435" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 50184.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.2 205.2 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTH2 TIP39 ENSG00000142538 "Parathyroid hormone 2" Q96A98 19 49422419-49423441 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "brain: 4.3" "Cell type enhanced" "Detected in some" "Early spermatids: 2.4;Late spermatids: 3.1;Muller glia cells: 2.4;Spermatocytes: 2.0;Spermatogonia: 2.0" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "olfactory bulb: 2.9" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (3.41e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.7 0.3 0.0 0.1 4.3 0.7 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 2.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 254.0;Basal squamous epithelial cells: 93.9;Breast glandular cells: 105.4;Breast myoepithelial cells: 56.3;Club cells: 77.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HaCaT: 291.3;HBEC3-KT: 359.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (1.67e-1)" "unprognostic (5.26e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.16e-2)" "unprognostic (4.09e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-9)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" "unprognostic (5.23e-3)" "unprognostic (7.87e-3)" 3.1 0.8 1.8 1.2 2.3 0.0 20.1 0.6 3.2 13.6 10.2 3.3 2.3 10.7 1.1 16.2 1.5 7.5 4.2 4.1 3.2 0.4 0.2 1.2 1.1 4.0 8.1 1.8 1.7 22.8 2.9 3.0 0.4 5.2 1.6 0.2 8.5 2.4 0.7 2.0 1.6 3.0 0.2 3.6 1.8 1.3 8.6 0.4 1.8 1.7 1.0 9.2 15.2 0.8 1.7 9.9 0.0 0.0 2.9 2.8 0.1 0.3 1.0 0.5 1.3 0.3 7.9 0.0 0.5 2.6 9.1 291.3 1.3 359.8 0.1 7.4 1.7 0.5 1.8 0.1 0.8 0.1 0.4 0.2 19.7 9.1 34.4 0.9 11.2 0.1 0.0 0.4 0.2 0.1 0.1 0.0 1.4 0.4 16.7 0.1 1.5 0.6 34.3 0.3 0.2 0.1 16.4 0.1 2.1 11.5 0.5 0.1 5.6 1.6 8.9 5.1 77.8 4.7 0.1 12.1 7.5 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.8 2.3 0.6 3.2 4.1 3.2 4.0 8.1 0.4 0.2 8.6 0.8 1.4 0.0 0.0 0.7 0.4 4.6 1.9 254.0 93.9 0.3 105.4 56.3 0.4 0.0 77.5 0.0 0.0 0.0 0.5 0.0 0.0 3.5 5.9 0.9 4.7 4.5 0.0 0.0 0.6 8.9 0.0 13.6 0.0 0.8 0.0 2.6 0.4 0.2 0.0 0.0 11.2 0.0 4.1 0.3 1.3 2.7 0.9 0.6 23.2 1.0 0.6 1.8 0.0 0.0 0.2 8.6 0.0 0.0 6.2 0.5 0.0 0.3 14.8 0.5 6.6 8.0 6.7 3.6 0.2 7.9 1.4 0.0 0.5 0.2 0.0 0.2 PTK7 CCK4 ENSG00000112655 "Protein tyrosine kinase 7 (inactive)" Q13308 6 43076307-43161719 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 317.3;Endometrial stromal cells: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 13.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 13.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003222 Approved "Secreted to blood" NA NA 12000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "HPA003222: AB_1079713" "unprognostic (1.80e-1)" "unprognostic (7.49e-3)" "unprognostic (6.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.65e-1)" "unprognostic (1.15e-2)" "unprognostic (5.85e-3)" "unprognostic (9.81e-3)" "unprognostic (1.47e-3)" "unprognostic (7.15e-2)" "unprognostic (5.11e-3)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.73e-1)" "unprognostic (3.61e-1)" "unprognostic (9.12e-2)" "unprognostic (5.70e-3)" 15.0 5.0 9.6 6.7 8.4 2.8 17.5 8.5 8.9 69.5 36.0 9.4 6.5 87.4 87.1 30.1 38.2 24.7 8.8 8.7 10.8 29.3 1.6 33.9 3.9 10.2 11.4 85.3 16.4 13.0 21.1 48.8 8.7 37.9 8.5 6.0 36.7 25.4 0.6 34.6 9.5 38.7 9.0 27.8 12.2 41.7 11.2 30.4 23.0 1.5 6.4 22.3 43.6 8.2 9.1 2.5 83.6 141.6 88.0 89.9 119.4 94.2 145.5 77.0 99.4 77.0 31.0 0.2 74.0 107.3 56.4 99.5 38.0 87.5 49.3 0.7 52.0 8.5 17.1 105.2 132.5 0.3 0.4 129.1 77.4 103.2 32.6 135.8 10.1 35.0 6.2 0.2 36.4 7.0 32.5 12.6 39.1 0.8 7.0 33.3 119.0 0.3 61.0 42.4 48.3 91.6 14.8 1.5 50.0 87.8 51.9 19.5 6.8 84.1 53.1 0.4 51.0 0.5 0.9 3.2 19.1 0.3 14.1 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.4 0.2 0.7 0.0 13.5 0.0 0.8 9.6 8.4 8.5 8.9 8.7 10.8 10.2 11.4 8.7 9.0 11.2 8.2 3.0 16.0 13.1 10.7 0.8 17.3 19.9 40.4 27.9 4.3 23.5 32.5 1.6 5.7 14.6 12.9 56.3 19.1 6.3 1.7 1.9 21.0 317.3 23.5 84.7 8.7 21.6 4.0 8.7 6.9 2.2 30.0 8.6 25.2 1.3 25.3 2.2 0.0 3.5 0.0 5.3 3.9 42.7 0.0 9.8 48.9 18.3 4.1 16.0 1.0 1.0 20.1 0.0 3.5 1.4 10.5 4.1 18.4 1.4 11.8 0.6 0.6 15.4 2.2 13.1 8.7 27.9 2.8 21.2 13.7 10.4 8.2 3.0 17.7 6.3 11.8 PTN "HBGF8, HBNF, NEGF1" ENSG00000105894 Pleiotrophin P21246 7 137227341-137343774 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 280.4;parathyroid gland: 383.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 672.0;Extravillous trophoblasts: 416.0;Horizontal cells: 526.6;Muller glia cells: 548.5;Oligodendrocyte precursor cells: 322.7;Squamous epithelial cells: 439.9" "Cancer enriched" "Detected in all" 11 "glioma: 514.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 12 "AF22: 1717.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017685, HPA073913" Enhanced Supported "Endoplasmic reticulum" "Secreted to blood" NA NA 167000 1400000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "Endoplasmic reticulum" "CAB017685: AB_1128556, HPA073913: " "unprognostic (1.51e-2)" "unprognostic (7.87e-2)" "unprognostic (5.44e-2)" "unprognostic (4.23e-2)" "unprognostic (1.92e-1)" "unprognostic (7.19e-2)" "unprognostic (2.81e-2)" "unprognostic (7.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.09e-2)" "unprognostic (3.86e-1)" "unprognostic (1.22e-2)" "prognostic favorable (1.35e-4)" "unprognostic (2.34e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" 26.2 18.2 212.9 4.1 206.4 0.1 82.3 217.0 280.4 100.0 182.0 31.4 5.4 76.8 55.3 78.2 19.2 55.9 87.7 209.6 205.2 38.4 8.5 18.4 7.4 220.3 200.5 19.0 8.4 383.5 126.1 36.2 196.3 116.1 21.6 63.4 37.4 52.5 2.2 9.1 10.1 54.0 204.2 40.4 15.7 53.8 207.6 21.4 18.9 18.8 11.4 24.8 65.1 209.1 1.2 0.0 1717.6 21.2 0.4 0.9 140.6 45.3 134.3 25.1 34.3 0.4 0.2 0.0 0.2 60.0 15.6 1.0 0.0 0.0 18.9 0.0 1.4 0.0 0.0 0.0 7.7 0.0 0.5 1.9 0.0 16.6 0.2 24.6 0.0 0.0 0.0 8.2 7.0 0.0 0.0 0.6 133.5 0.0 1.1 0.1 2.8 0.4 0.7 0.0 8.0 116.5 0.0 0.0 0.2 24.1 0.2 0.2 0.0 37.4 32.9 1.8 99.4 0.7 0.0 0.0 119.7 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 212.9 206.4 217.0 280.4 209.6 205.2 220.3 200.5 196.3 204.2 207.6 209.1 10.1 0.0 0.0 303.3 1.3 23.2 1.7 85.0 209.5 27.7 244.6 117.3 14.6 2.8 20.9 1.8 6.2 220.0 2.2 0.0 9.8 1.1 24.5 53.4 672.0 32.0 0.0 0.0 4.9 0.0 416.0 248.8 0.5 24.6 0.0 1.1 7.1 0.3 20.4 526.6 18.1 0.0 0.0 0.3 20.6 14.0 172.7 4.0 44.4 102.1 0.0 548.5 0.0 322.7 218.4 0.3 0.0 185.5 2.5 18.6 0.0 7.5 7.2 32.3 59.2 3.0 91.4 4.0 2.4 439.9 13.9 193.3 4.4 144.7 0.0 2.2 PTPRA "HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA" ENSG00000132670 "Protein tyrosine phosphatase receptor type A" P18433 20 2864184-3039076 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029412, CAB034366, HPA069480" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB034366: AB_2269058, HPA029412: AB_10602293, HPA069480: AB_2686141" "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" "unprognostic (4.58e-2)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (5.43e-3)" "unprognostic (5.34e-2)" "unprognostic (1.55e-1)" "unprognostic (3.24e-1)" "unprognostic (7.33e-2)" "unprognostic (1.16e-1)" "prognostic favorable (3.29e-6)" "unprognostic (1.25e-1)" "unprognostic (4.02e-1)" "unprognostic (1.60e-2)" "unprognostic (4.19e-1)" 48.8 36.6 83.9 31.9 89.3 39.6 47.4 84.2 96.1 56.4 59.5 41.6 31.0 53.0 36.7 46.1 52.7 43.7 29.5 87.7 83.5 44.2 28.6 45.4 38.9 74.7 81.9 55.8 31.2 81.9 44.8 60.8 78.3 46.3 40.6 61.5 36.3 41.9 16.9 45.8 32.7 52.4 76.3 39.4 34.5 43.4 92.6 59.6 65.5 30.7 44.3 46.6 38.9 81.1 74.0 44.2 124.7 38.4 134.4 243.3 26.5 54.1 105.1 65.5 79.6 53.1 99.5 48.1 41.6 73.1 66.1 77.2 51.0 77.4 73.4 74.7 32.7 68.5 18.3 68.0 48.1 69.5 31.1 109.8 78.2 54.4 56.8 80.3 92.0 67.7 69.9 59.7 65.8 30.4 80.8 78.3 48.3 66.0 35.0 61.0 60.5 60.3 55.1 56.2 68.7 65.7 52.3 87.8 81.4 54.0 55.2 58.7 66.5 58.1 28.6 65.6 48.5 43.4 64.7 62.7 26.9 64.5 55.7 5.7 2.8 4.8 6.1 2.9 4.9 5.3 4.0 4.4 2.1 2.6 4.0 4.8 3.3 4.0 4.3 3.2 4.9 2.3 83.9 89.3 84.2 96.1 87.7 83.5 74.7 81.9 78.3 76.3 92.6 81.1 87.0 22.4 19.2 128.6 46.7 15.8 34.0 15.0 34.7 88.9 49.0 43.9 10.1 54.3 24.5 46.0 31.3 35.3 111.7 39.8 27.4 14.8 17.0 62.0 109.0 39.7 44.3 42.3 138.2 15.8 40.5 67.5 25.0 55.3 22.9 60.3 43.5 33.6 39.4 70.7 136.4 27.9 24.4 37.6 20.4 17.2 60.3 40.1 37.4 52.5 29.9 88.3 110.2 102.5 147.5 16.6 30.2 48.9 58.6 32.9 27.1 23.6 26.6 60.5 39.5 53.3 61.8 68.7 84.1 32.9 17.2 32.7 59.7 41.4 30.4 31.5 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase receptor type C" P08575 1 198638457-198757476 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 208.6;lymphoid tissue: 329.9" "Cell type enhanced" "Detected in many" "B-cells: 525.2;dendritic cells: 1026.4;Macrophages: 534.1;monocytes: 554.9;NK-cells: 769.3;Plasma cells: 474.2;T-cells: 1049.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 209.9;HEL: 118.0;HL-60: 108.1;JURKAT: 266.4;MOLT-4: 161.1;THP-1: 87.0;U-266/70: 93.7;U-266/84: 91.2;U-698: 123.4;U-937: 94.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 24000000 "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, HPA000440: AB_611377" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (5.10e-3)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (3.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.08e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (6.41e-2)" "unprognostic (7.06e-2)" 32.8 11.6 3.8 248.5 3.3 208.6 13.9 4.4 4.3 14.9 6.9 26.4 27.4 11.3 5.6 15.1 8.4 45.7 7.3 3.5 5.6 7.0 29.6 68.6 329.9 12.9 8.6 5.7 5.6 4.0 2.9 23.5 11.5 11.6 30.5 2.0 13.8 6.6 4.6 5.7 42.9 25.3 7.9 202.5 37.9 5.5 6.9 306.9 7.0 7.6 251.2 62.1 5.2 14.7 0.4 0.0 0.2 0.2 0.0 0.0 0.8 0.3 0.3 0.1 0.0 0.0 0.1 209.9 0.3 0.7 0.2 0.3 0.0 0.2 0.4 0.6 0.0 118.0 0.2 0.1 0.0 108.1 0.7 0.0 0.0 0.3 0.0 0.4 0.5 266.4 2.4 3.3 0.3 0.1 161.1 65.0 0.5 0.2 0.2 4.6 0.4 0.3 0.1 0.1 1.2 1.8 0.1 0.4 0.5 0.2 0.3 87.0 1.3 0.0 0.8 0.8 0.4 93.7 91.2 123.4 0.1 94.5 0.4 226.1 480.0 521.4 634.4 885.8 541.8 249.0 437.0 618.1 385.8 245.8 489.8 494.1 844.3 506.9 1015.8 57.4 508.6 1340.6 3.8 3.3 4.4 4.3 3.5 5.6 12.9 8.6 11.5 7.9 6.9 14.7 12.6 44.8 62.3 0.7 525.2 15.8 0.9 0.0 4.0 0.3 6.0 9.3 4.6 5.7 14.2 1.8 0.0 0.6 1026.4 1.0 0.0 0.7 2.4 2.3 2.3 15.1 1.2 58.8 0.7 0.0 0.9 17.2 46.9 2.7 246.5 0.1 14.6 6.9 96.0 0.0 1.7 0.4 0.0 334.9 214.5 3.5 1.2 534.1 21.4 201.4 554.9 0.1 769.3 2.5 0.7 0.1 0.8 0.0 474.2 1.1 0.1 2.5 11.7 0.2 6.6 7.4 6.7 0.3 0.6 1.8 15.2 0.8 1049.1 5.4 0.9 0.8 PTPRCAP "CD45-AP, LPAP" ENSG00000213402 "Protein tyrosine phosphatase receptor type C associated protein" Q14761 11 67435510-67437682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 79.7;lymphoid tissue: 174.1" "Group enriched" "Detected in some" 6 "B-cells: 203.3;Plasma cells: 283.5;T-cells: 233.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 351.1;HDLM-2: 242.3;HL-60: 140.6;MOLT-4: 206.8;NB-4: 996.9;U-698: 248.9" "Region enhanced" "Detected in single" "basal ganglia: 1.0" "Low region specificity" "Detected in many" HPA043734 Enhanced Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA043734: AB_10962214" 7.1 2.9 3.0 73.0 2.9 27.0 5.3 2.6 4.9 7.0 3.1 14.3 14.0 4.6 0.0 7.9 7.9 3.0 3.5 2.5 2.5 9.9 8.9 14.4 126.5 3.9 2.8 5.0 3.8 0.3 4.2 0.6 3.4 10.6 2.4 0.0 10.2 0.6 2.2 4.2 79.7 0.9 3.4 174.1 24.7 1.5 3.0 109.2 13.0 0.2 51.3 7.5 7.0 3.5 0.4 1.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.2 351.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 242.3 0.5 0.2 0.9 0.0 0.0 140.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 95.5 1.1 33.3 0.1 3.7 206.8 996.9 0.0 0.0 0.3 65.8 0.2 0.6 0.0 1.1 0.2 0.4 0.2 0.0 1.1 0.0 0.6 0.3 1.4 0.0 1.5 0.0 0.3 0.3 0.3 248.9 0.0 0.3 0.1 23.6 6.7 75.0 1559.9 5.6 1322.2 1334.4 955.3 1380.5 12.7 1714.2 688.5 1083.9 33.4 826.7 8.0 848.7 1374.2 1237.9 3.0 2.9 2.6 4.9 2.5 2.5 3.9 2.8 3.4 3.4 3.0 3.5 0.0 0.0 0.0 7.2 203.3 12.7 0.0 0.9 1.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 15.1 0.2 0.0 0.0 4.4 17.9 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.3 20.6 0.0 0.0 5.0 39.2 7.5 0.5 0.0 1.0 0.5 3.1 0.0 0.0 0.0 283.5 0.0 0.0 0.1 1.4 0.0 0.0 0.0 3.5 0.0 0.0 1.6 9.7 0.0 233.3 0.0 0.0 0.0 PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase receptor type D" P23468 9 8314246-10612723 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.8" "Group enriched" "Detected in many" 12 "Excitatory neurons: 4579.7;Inhibitory neurons: 1152.9;Oligodendrocyte precursor cells: 1170.2;Oligodendrocytes: 3151.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 21.1;HAP1: 4.3;HSkMC: 6.3;RH-30: 8.1;SCLC-21H: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 20000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA054829: AB_2682618" "unprognostic (4.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.44e-2)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (9.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.13e-2)" "unprognostic (7.52e-3)" "unprognostic (2.62e-1)" "prognostic favorable (7.45e-6)" "unprognostic (3.56e-4)" "unprognostic (7.59e-2)" "unprognostic (4.84e-2)" "unprognostic (3.08e-3)" 2.1 0.6 10.8 0.3 24.7 0.1 0.9 12.2 26.2 5.6 0.0 3.3 1.8 2.4 0.2 0.6 2.2 1.0 2.5 14.4 7.2 6.6 3.6 4.6 0.0 14.6 10.1 12.1 1.3 18.7 4.3 5.3 19.1 1.9 2.5 6.4 0.5 0.6 0.9 0.7 5.0 1.0 10.4 0.4 0.9 1.6 17.6 0.7 3.4 0.8 0.0 2.2 3.4 70.8 0.0 0.1 21.1 0.0 0.3 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 2.7 3.6 0.5 0.0 0.0 0.0 0.1 6.3 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.6 0.0 3.4 0.0 3.2 2.3 8.1 0.0 1.8 0.0 4.8 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 24.7 12.2 26.2 14.4 7.2 14.6 10.1 19.1 10.4 17.6 70.8 0.5 0.0 3.2 199.2 0.1 0.5 0.4 3.2 6.2 134.2 0.3 0.1 6.5 27.1 1.8 5.5 16.7 0.3 0.0 16.4 0.0 3.6 15.8 0.8 15.0 1.2 35.4 0.0 4579.7 0.0 0.3 15.5 0.5 1.0 0.0 9.2 1.4 13.5 1.3 5.0 1152.9 13.2 0.0 0.8 0.0 6.5 15.8 1.6 0.0 85.3 0.1 36.1 0.0 1170.2 3151.1 0.2 9.2 0.0 2.7 2.1 18.3 26.3 0.2 7.8 0.0 4.0 5.8 2.4 3.2 0.4 0.9 0.3 0.8 6.0 8.7 0.1 PTPRE PTPE ENSG00000132334 "Protein tyrosine phosphatase receptor type E" P23469 10 127907103-128085855 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 46.9" "Cell type enhanced" "Detected in many" "dendritic cells: 256.6;Inhibitory neurons: 191.6;Langerhans cells: 307.9;Macrophages: 276.3;Oligodendrocyte precursor cells: 247.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 634.6;plasmacytoid DC: 475.9" "Group enriched" "Detected in all" 12 "dendritic cells: 475.9;granulocytes: 634.6;monocytes: 175.4" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 38.6;HUVEC TERT2: 41.6;NB-4: 32.5;TIME: 79.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015870, HPA021872" Supported Approved "Intermediate filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Intermediate filaments" "HPA015870: AB_1855759, HPA021872: AB_1855760" "unprognostic (5.23e-2)" "unprognostic (1.37e-1)" "unprognostic (1.99e-1)" "unprognostic (7.11e-2)" "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (6.50e-2)" "unprognostic (4.49e-2)" "unprognostic (2.11e-1)" "unprognostic (2.56e-2)" "unprognostic (8.71e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (4.08e-5)" "unprognostic (1.52e-1)" "unprognostic (6.71e-3)" "unprognostic (2.49e-2)" "unprognostic (5.59e-2)" 13.6 16.7 13.9 25.3 8.9 46.9 6.7 5.7 13.9 3.9 7.7 9.2 9.5 3.5 2.6 7.9 4.9 10.3 10.6 14.2 11.1 4.3 4.4 16.0 16.4 11.6 9.0 1.6 2.7 2.7 5.0 7.8 10.7 3.4 9.3 1.0 5.8 2.4 1.3 4.7 12.9 7.4 10.8 20.6 7.4 2.6 10.7 8.6 5.5 3.1 9.8 12.7 4.4 14.2 4.3 0.9 0.5 0.0 2.5 0.4 7.5 0.1 0.0 1.6 3.6 1.7 25.1 3.3 2.6 2.1 5.2 2.3 2.1 12.2 0.7 4.0 1.9 0.4 1.4 0.0 4.1 16.2 11.6 0.8 6.9 6.1 12.1 38.6 41.6 10.3 0.0 1.9 2.6 4.0 4.9 32.5 0.2 4.6 1.5 19.1 2.6 6.4 6.8 18.0 0.0 2.5 7.4 1.3 0.3 1.8 0.6 20.1 79.5 1.7 1.8 7.8 8.9 0.9 1.3 4.6 11.3 12.5 0.0 174.3 175.4 147.2 36.6 64.5 22.3 7.7 16.5 25.1 97.9 8.3 11.5 19.6 634.6 31.6 54.9 475.9 26.7 43.3 13.9 8.9 5.7 13.9 14.2 11.1 11.6 9.0 10.7 10.8 10.7 14.2 25.0 83.3 57.2 22.5 26.2 59.5 54.3 42.4 15.9 5.2 14.2 23.6 20.3 8.6 23.7 3.7 0.0 43.2 256.6 15.7 0.0 3.7 2.1 3.6 10.6 78.0 6.7 10.3 112.7 4.4 67.4 17.5 10.7 7.7 31.6 3.7 47.5 2.3 57.5 0.0 191.6 15.8 18.3 166.7 307.9 2.5 0.6 276.3 24.9 165.8 139.5 0.0 150.4 247.3 93.4 49.2 13.3 0.4 38.5 21.3 13.9 2.2 7.8 0.9 0.0 86.0 12.8 0.5 1.9 20.4 64.6 17.0 59.3 9.2 11.7 40.3 PTPRF LAR ENSG00000142949 "Protein tyrosine phosphatase receptor type F" P10586 1 43525187-43623666 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 259.9;Extravillous trophoblasts: 290.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 314.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012710 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" NA NA 160000000 "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA012710: AB_1855933" "unprognostic (8.20e-2)" "unprognostic (2.41e-2)" "unprognostic (3.01e-2)" "unprognostic (9.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.59e-1)" "unprognostic (1.51e-1)" "unprognostic (4.97e-2)" "unprognostic (4.68e-2)" "unprognostic (7.07e-2)" "unprognostic (1.99e-2)" "prognostic favorable (7.03e-4)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.58e-1)" 91.7 11.9 47.1 14.0 48.4 1.8 57.4 22.3 45.6 36.3 4.7 79.5 70.5 28.0 71.9 101.7 70.5 30.4 7.6 45.3 39.9 27.7 107.2 35.4 4.7 33.1 43.6 22.1 56.8 31.1 23.5 55.7 33.1 67.3 51.4 24.7 101.7 43.1 2.7 107.9 78.5 35.0 30.4 4.0 49.7 9.4 45.6 29.6 23.8 3.4 26.2 40.0 51.2 37.4 165.6 76.5 49.0 58.0 11.2 0.6 274.3 92.1 36.1 73.9 62.6 82.0 214.9 0.4 25.6 40.2 59.2 124.7 57.5 200.7 89.1 2.0 72.1 1.0 48.7 75.3 33.8 1.2 1.3 11.3 113.2 106.4 174.9 92.6 111.5 7.7 25.4 7.1 27.5 94.0 1.2 1.3 75.9 89.8 21.0 57.2 86.9 3.7 28.3 241.5 73.3 28.0 90.8 314.0 11.8 128.8 91.5 17.3 88.2 1.6 116.5 7.5 126.1 3.1 2.7 0.4 7.4 3.9 233.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.1 48.4 22.3 45.6 45.3 39.9 33.1 43.6 33.1 30.4 45.6 37.4 2.3 157.0 101.1 39.2 2.3 62.8 51.3 67.4 52.9 33.5 146.3 102.9 7.6 130.1 74.9 86.5 43.8 64.3 1.4 259.9 0.0 147.4 4.9 80.6 17.2 7.7 100.9 8.0 40.6 120.8 290.1 19.8 93.8 70.6 5.1 72.8 10.4 159.6 14.1 185.1 16.1 171.7 50.8 4.9 5.8 8.5 6.8 3.4 12.4 7.5 2.9 27.2 2.1 16.6 68.1 165.0 124.7 7.2 1.8 68.0 208.1 13.9 128.3 31.0 0.0 15.8 18.5 9.0 37.5 107.5 91.4 66.2 3.9 9.6 142.5 78.7 PTPRJ "CD148, DEP1, HPTPeta" ENSG00000149177 "Protein tyrosine phosphatase receptor type J" Q12913 11 47980558-48170841 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 167.5;Microglial cells: 189.3;Oligodendrocyte precursor cells: 239.8;Oligodendrocytes: 167.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.5" "Group enriched" "Detected in many" 4 "granulocytes: 9.5;monocytes: 4.7" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 52.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006026 Approved "Intracellular and membrane" NA NA 670000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "HPA006026: AB_1078446" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-2)" "unprognostic (3.20e-2)" "unprognostic (2.99e-2)" "unprognostic (6.58e-2)" "unprognostic (2.15e-1)" "unprognostic (9.64e-3)" "unprognostic (3.79e-3)" "unprognostic (5.16e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.13e-5)" "unprognostic (1.09e-2)" "unprognostic (7.98e-2)" "unprognostic (9.18e-2)" "unprognostic (2.00e-1)" 6.0 3.2 10.2 20.5 13.8 29.5 6.1 6.9 14.9 6.2 18.5 10.2 9.4 2.4 7.8 1.9 4.1 7.1 2.7 10.0 12.7 13.9 11.9 10.0 15.5 9.7 11.7 1.6 6.1 15.8 10.1 7.6 12.4 7.9 8.7 8.1 10.1 7.0 2.4 4.2 14.5 5.9 6.0 23.3 14.6 2.3 18.5 7.0 19.6 2.7 11.0 6.9 2.1 14.7 7.6 28.3 12.1 7.0 1.9 4.1 4.2 7.5 5.5 12.9 9.2 2.0 40.8 6.9 51.8 19.1 19.6 6.0 19.0 2.0 14.9 46.6 5.4 1.9 34.9 2.8 12.1 2.7 41.5 3.2 0.6 3.8 1.0 31.7 7.8 0.5 2.6 4.4 4.7 17.0 0.1 17.3 9.7 25.7 4.4 1.6 1.6 4.0 52.6 11.1 7.9 2.5 20.2 12.0 19.4 8.9 13.0 20.3 25.7 9.9 10.8 20.5 23.4 1.1 1.7 11.4 11.7 8.0 37.3 0.7 1.1 2.8 1.6 2.0 1.0 0.8 0.9 1.2 0.8 0.5 0.7 0.9 9.5 1.0 4.7 1.5 1.0 0.8 10.2 13.8 6.9 14.9 10.0 12.7 9.7 11.7 12.4 6.0 18.5 14.7 1.5 9.6 16.7 43.1 11.3 0.3 9.8 0.8 0.6 13.6 8.3 4.1 3.7 17.2 13.0 38.6 6.2 1.9 32.7 35.5 0.0 7.4 5.5 13.5 2.2 4.5 12.6 3.2 81.0 5.0 0.6 4.0 22.4 22.9 13.9 2.5 5.0 15.6 30.0 10.1 167.5 10.1 2.0 74.2 5.7 8.2 0.3 40.2 1.8 189.3 36.0 10.3 21.6 239.8 167.7 11.8 28.0 0.4 12.9 25.3 37.6 13.5 4.9 1.3 0.0 3.3 4.9 0.2 4.8 0.5 0.3 1.9 22.0 2.3 7.6 8.2 PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase receptor type O" Q16827 12 15322257-15602175 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.8;kidney: 36.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 193.6;Inhibitory neurons: 231.1;Oligodendrocyte precursor cells: 126.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 9.9;NTERA-2: 5.8;SH-SY5Y: 6.1;THP-1: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 175.9" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 1.8 0.8 8.7 3.0 9.4 0.2 0.8 0.0 10.3 1.3 0.1 10.4 1.7 4.8 1.4 0.4 1.0 1.2 0.5 9.8 8.9 36.3 1.3 6.8 3.1 2.2 3.3 0.4 0.4 0.3 2.4 4.4 5.3 0.5 26.8 7.5 0.5 0.8 0.3 0.4 2.0 6.6 0.9 3.4 0.8 0.5 9.5 1.2 0.3 0.5 3.2 1.5 0.4 2.9 0.0 0.1 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.5 1.3 0.0 0.0 0.1 0.1 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 5.8 1.2 0.0 0.0 0.0 0.0 0.1 0.2 1.5 6.1 0.9 0.0 0.1 0.1 0.1 2.7 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.0 0.1 1.2 0.0 6.0 0.0 0.0 12.3 0.0 8.9 1.7 0.4 8.5 8.6 2.8 1.2 0.1 0.1 12.7 10.9 1.4 3.2 8.7 9.4 0.0 10.3 9.8 8.9 2.2 3.3 5.3 0.9 9.5 2.9 0.2 0.0 0.5 7.5 7.0 0.3 1.3 0.5 0.0 25.2 0.0 0.1 0.7 0.0 1.8 16.5 0.0 0.2 4.0 3.9 0.0 0.4 0.0 0.8 0.2 1.1 3.6 0.0 193.6 0.0 0.2 0.9 0.0 0.6 0.0 0.0 1.1 0.2 26.1 25.2 231.1 8.3 0.0 21.1 10.6 0.6 0.6 10.5 0.0 17.8 13.8 0.6 1.0 126.7 6.3 0.1 9.8 0.4 1.0 0.1 0.1 0.2 0.0 4.8 0.0 2.1 0.7 0.6 1.1 0.1 0.4 0.3 1.0 0.1 22.4 0.8 PTPRS ENSG00000105426 "Protein tyrosine phosphatase receptor type S" Q13332 19 5158495-5340803 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 76.8;Inhibitory neurons: 104.2;Melanocytes: 80.0;Oligodendrocytes: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 89 "plasmacytoid DC: 12.5" "Lineage enriched" "Detected in single" 89 "dendritic cells: 12.5" "Cell line enhanced" "Detected in many" "AN3-CA: 121.8;HaCaT: 124.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" NA NA 150000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA054747: AB_2682591" "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" 54.7 21.2 34.4 5.0 25.5 1.5 36.2 3.2 30.9 40.2 0.0 25.2 2.6 30.5 2.2 16.5 41.1 13.7 37.0 34.3 10.0 11.2 6.0 26.9 5.5 16.4 16.4 35.8 32.4 9.7 29.1 2.3 17.6 30.5 1.6 5.7 18.6 14.6 14.4 20.6 13.6 8.6 1.6 9.0 23.2 9.9 27.3 4.2 29.4 7.4 4.4 32.0 31.8 34.9 11.3 64.0 56.2 121.8 25.3 20.5 7.4 19.4 22.5 22.8 18.5 0.7 6.2 0.2 44.5 32.2 18.0 124.6 15.1 0.2 10.0 1.5 24.3 0.0 27.2 40.5 11.7 0.0 14.1 21.8 5.4 4.8 0.9 29.4 0.6 7.9 18.5 0.2 9.1 48.0 5.2 12.3 31.7 0.4 27.0 0.0 12.4 0.0 4.7 22.5 43.1 58.9 18.3 3.4 34.6 10.7 22.0 4.8 2.8 20.2 34.3 46.9 23.6 6.2 0.1 36.9 10.5 0.0 44.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 34.4 25.5 3.2 30.9 34.3 10.0 16.4 16.4 17.6 1.6 27.3 34.9 1.1 6.4 1.1 53.8 3.2 60.9 42.4 16.1 22.2 49.6 3.3 5.5 14.1 27.1 4.9 12.9 2.1 0.7 56.4 0.1 9.8 1.4 3.4 5.4 11.4 9.7 3.0 0.0 76.8 0.9 32.2 51.2 5.1 5.3 0.0 4.0 25.4 20.2 1.7 11.8 104.2 0.0 10.2 0.3 20.0 5.4 46.6 3.4 80.0 15.9 0.8 46.6 0.0 71.9 90.2 0.5 0.0 36.1 6.3 35.0 0.0 2.9 1.7 10.1 13.1 46.4 22.6 7.4 14.8 16.8 36.7 1.0 2.0 2.7 0.4 30.0 PTTG1IP "C21orf1, C21orf3, PBF" ENSG00000183255 "PTTG1 interacting protein" P53801 21 44849585-44873903 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034146, HPA061827" Uncertain Supported Nucleoplasm NA Yes 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB034146: AB_1568894, HPA061827: AB_2684620" "unprognostic (1.78e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (5.24e-3)" "unprognostic (3.18e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-2)" "unprognostic (3.59e-2)" "unprognostic (1.22e-2)" "unprognostic (1.98e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (9.30e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (5.40e-4)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.90e-1)" 127.8 131.8 147.6 98.4 158.9 92.0 114.0 150.8 146.8 131.1 131.1 132.7 123.2 132.4 118.5 89.1 109.4 141.8 164.3 138.1 168.7 157.6 130.5 160.5 75.3 178.8 152.9 110.7 85.6 84.1 68.8 180.1 169.9 108.5 111.5 29.7 118.3 151.4 70.7 88.9 127.3 145.0 152.0 97.7 169.9 66.9 175.3 57.9 127.4 63.2 62.0 139.6 93.3 157.5 245.3 134.6 155.3 148.2 300.6 174.8 127.0 212.9 309.8 174.1 166.6 290.0 323.9 32.9 789.8 344.4 417.0 109.8 73.0 140.2 161.1 56.3 81.0 254.3 80.0 260.1 293.8 97.6 83.5 269.9 225.1 189.1 130.8 346.3 376.6 88.6 131.7 83.1 539.5 106.0 71.0 99.5 166.8 352.9 169.8 70.4 158.4 162.0 735.6 82.7 117.2 182.0 240.0 262.5 482.0 188.7 203.7 163.7 511.8 216.9 126.5 170.6 340.0 78.5 79.4 42.2 146.7 220.6 199.8 336.2 181.2 109.1 48.4 146.7 79.5 25.5 62.7 51.3 203.3 23.6 59.7 41.0 248.8 67.3 167.0 92.5 87.3 223.7 147.6 158.9 150.8 146.8 138.1 168.7 178.8 152.9 169.9 152.0 175.3 157.5 140.9 394.2 169.6 39.8 28.0 50.7 84.1 181.3 61.5 14.6 102.0 96.8 173.0 75.8 248.9 145.3 6.2 218.6 56.8 321.4 49.0 323.0 51.5 115.0 115.0 191.6 79.3 37.8 8.5 120.6 72.7 117.1 140.6 187.7 81.5 181.3 124.2 102.2 109.3 11.8 10.7 89.1 130.2 88.0 69.6 98.7 72.1 136.3 87.2 22.5 91.1 78.8 51.5 20.1 31.9 294.3 255.2 98.9 36.4 112.8 268.1 71.2 192.3 15.2 65.7 61.1 127.9 73.7 43.4 92.4 42.9 366.7 45.6 54.6 100.3 169.9 PTX3 "TNFAIP5, TSG-14" ENSG00000163661 "Pentraxin 3" P26022 3 157436850-157443633 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 231.5;urinary bladder: 191.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 16.2;Fibroblasts: 44.7;Glandular and luminal cells: 24.0;Langerhans cells: 23.6;Macrophages: 27.0;Melanocytes: 14.2" "Cancer enhanced" "Detected in many" "glioma: 22.5" "Group enriched" "Detected in some" 4 "cerebral cortex: 1.9;thalamus: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1219.3;ASC TERT1: 1751.7;BJ hTERT+: 1201.8;HHSteC: 2261.1;HSkMC: 2364.2;hTEC/SVTERT24-B: 1276.5;TIME: 1761.1;U-2197: 1605.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069320 Approved Approved "Plasma membrane" "Secreted to blood" NA NA 1090000 970000 "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA069320: AB_2686118" "unprognostic (1.93e-2)" "unprognostic (4.96e-3)" "unprognostic (1.35e-1)" "prognostic unfavorable (8.35e-9)" "unprognostic (5.79e-3)" "prognostic unfavorable (6.36e-4)" "unprognostic (6.03e-3)" "prognostic unfavorable (8.75e-6)" "unprognostic (2.45e-1)" "unprognostic (6.69e-2)" "unprognostic (7.60e-2)" "unprognostic (2.63e-1)" "unprognostic (2.76e-9)" "unprognostic (6.03e-3)" "unprognostic (5.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.92e-3)" 231.5 11.1 0.4 38.8 0.4 89.0 57.9 0.6 1.9 2.8 1.1 13.0 0.8 2.5 0.5 2.9 21.4 7.7 46.8 0.6 0.5 6.8 2.6 83.2 0.9 0.7 0.6 1.4 41.6 1.1 4.4 11.4 0.6 6.9 2.3 0.4 5.4 0.5 5.2 25.4 9.7 5.7 0.3 23.6 24.8 0.7 4.0 1.6 5.8 0.5 0.3 191.7 3.1 0.4 1.2 0.0 752.4 0.2 1219.3 1751.7 0.3 132.3 1201.8 56.2 60.9 0.7 7.9 0.2 460.6 157.4 87.6 0.0 0.3 1.1 110.5 0.8 0.3 2.0 0.1 0.0 2261.1 2.5 0.0 2364.2 0.8 1276.5 429.8 110.2 266.4 0.1 0.3 0.0 380.1 0.0 0.3 2.9 11.2 0.0 4.6 0.2 0.0 0.2 5.3 53.1 6.0 0.8 7.6 1.0 0.9 0.1 0.6 2.4 1761.1 252.2 12.2 1605.1 23.0 0.2 0.5 0.9 52.8 6.4 74.2 0.0 0.3 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.6 1.9 0.6 0.5 0.7 0.6 0.6 0.3 4.0 0.4 2.3 0.0 1.7 0.0 0.1 1.7 1.7 0.3 0.0 1.8 3.6 0.6 0.6 0.0 1.3 0.0 0.0 0.1 0.1 0.0 0.0 7.2 2.4 16.2 10.3 5.1 0.0 0.0 0.5 0.0 0.1 44.7 0.0 24.0 0.0 0.7 3.3 0.0 2.6 0.0 1.0 0.0 0.0 10.0 23.6 1.2 0.3 27.0 14.2 0.0 2.3 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 1.0 0.0 0.2 0.0 0.8 0.0 4.0 7.2 0.0 0.4 0.4 1.0 0.3 0.4 0.0 0.0 0.4 PTX4 C16orf38 ENSG00000251692 "Pentraxin 4" Q96A99 16 1485886-1488981 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "brain: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HL-60: 21.2;NB-4: 15.7" "Region enhanced" "Detected in single" "hypothalamus: 1.0" "Low region specificity" "Detected in all" HPA073694 Supported "Secreted - unknown location" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 24: NB-4 - Immune response" "HPA073694: AB_2732237" "unprognostic (1.04e-1)" "unprognostic (2.66e-1)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (1.12e-1)" "unprognostic (1.84e-4)" "unprognostic (3.98e-2)" "unprognostic (5.66e-2)" "unprognostic (1.10e-1)" "unprognostic (3.09e-1)" "unprognostic (1.39e-2)" "unprognostic (3.54e-1)" "unprognostic (1.52e-4)" "unprognostic (2.23e-3)" "unprognostic (4.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.03e-1)" 0.1 0.2 0.6 0.0 0.2 0.7 0.0 0.2 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.5 3.1 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 21.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 15.7 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.2 0.2 0.3 0.4 0.8 1.5 3.1 2.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PUF60 "FIR, RoBPI, SIAHBP1" ENSG00000179950 "Poly(U) binding splicing factor 60" Q9UHX1 8 143816344-143829352 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Repressor, Ribonucleoprotein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 332.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045733, HPA052096, HPA059714" Enhanced Enhanced Nucleoplasm NA NA 70000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA045733: AB_10960503, HPA052096: AB_2681722, HPA059714: AB_2684110" "unprognostic (3.49e-2)" "unprognostic (8.78e-2)" "unprognostic (2.66e-1)" "unprognostic (4.05e-2)" "unprognostic (1.81e-2)" "unprognostic (3.47e-2)" "unprognostic (1.51e-2)" "unprognostic (4.34e-3)" "unprognostic (2.64e-2)" "unprognostic (1.07e-2)" "unprognostic (1.75e-1)" "unprognostic (5.45e-2)" "unprognostic (2.36e-2)" "unprognostic (2.64e-2)" "unprognostic (7.00e-2)" "unprognostic (2.28e-2)" "unprognostic (3.42e-2)" 71.6 73.5 7.9 11.0 7.6 39.6 75.5 8.1 22.9 71.4 5.3 84.8 22.3 84.9 5.9 84.9 76.3 7.3 88.5 7.8 15.4 82.8 124.3 64.0 17.7 12.2 11.6 57.2 62.9 11.7 71.0 19.2 14.1 67.2 5.8 1.3 63.3 17.8 125.5 108.7 69.5 10.5 7.3 72.3 73.2 70.8 14.5 15.9 59.8 9.0 9.7 74.5 68.6 12.4 95.7 211.5 36.7 31.3 16.6 15.6 62.7 74.4 27.4 70.3 75.1 95.4 103.9 89.4 71.2 58.9 52.8 83.0 86.5 91.4 3.6 91.4 147.7 110.2 117.0 106.3 60.4 38.5 70.0 45.4 61.8 89.8 26.9 21.1 69.0 92.1 88.7 37.4 20.5 332.5 156.1 26.4 77.8 63.3 191.6 84.2 42.9 91.8 19.5 91.8 71.5 80.3 101.6 40.4 77.7 9.1 116.7 21.4 79.0 72.9 176.2 85.7 98.6 66.7 103.9 109.7 70.7 73.3 71.9 90.8 112.6 99.8 129.0 133.7 139.3 116.8 103.1 128.6 127.1 135.9 98.6 113.1 58.8 132.6 137.6 76.8 139.0 193.9 7.9 7.6 8.1 22.9 7.8 15.4 12.2 11.6 14.1 7.3 14.5 12.4 70.2 38.5 46.4 21.5 64.7 107.7 102.1 197.4 65.4 62.8 51.3 67.9 63.7 51.5 103.0 29.5 29.2 146.6 56.4 98.0 92.0 110.7 20.5 65.6 55.3 67.3 66.9 65.0 8.2 89.8 134.3 68.4 74.9 60.3 55.8 75.0 41.7 76.8 101.1 43.7 8.3 75.9 118.0 44.0 62.3 47.8 64.0 52.3 90.7 6.5 105.2 182.6 81.4 9.5 23.7 98.2 91.4 59.0 52.7 83.0 91.9 118.1 85.4 64.8 65.7 57.1 122.9 104.2 128.5 63.1 107.1 173.3 74.2 99.3 97.7 81.2 PVR "CD155, HVED, Necl-5, NECL5, PVS, Tage4" ENSG00000073008 "PVR cell adhesion molecule" P15151 19 44643798-44666162 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 4.5;intermediate monocyte: 4.5;myeloid DC: 3.8;non-classical monocyte: 5.5" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;monocytes: 5.5" "Cell line enhanced" "Detected in many" "TIME: 175.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012568, HPA064739" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Secreted - unknown location" NA NA 720000000 "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles, Plasma membrane" "HPA012568: AB_1846248, HPA064739: " "unprognostic (2.90e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.36e-1)" "unprognostic (2.34e-1)" "unprognostic (7.89e-2)" "unprognostic (2.45e-3)" "unprognostic (3.06e-2)" "prognostic unfavorable (9.30e-4)" "unprognostic (9.05e-3)" "unprognostic (1.69e-1)" "unprognostic (2.09e-3)" "unprognostic (2.64e-3)" "unprognostic (1.69e-1)" "unprognostic (4.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-3)" "prognostic unfavorable (2.75e-4)" 13.9 17.5 10.2 7.1 9.1 5.1 9.6 9.0 10.0 8.7 9.3 10.3 12.5 13.9 5.2 8.4 11.8 6.2 28.5 9.0 16.6 13.6 30.7 19.4 2.7 9.7 11.0 12.5 14.0 10.3 17.3 12.5 12.4 9.7 8.8 5.4 9.9 6.4 19.0 7.1 11.1 10.5 7.4 4.6 12.3 5.8 14.9 2.5 10.6 6.2 2.8 9.1 8.5 7.9 58.8 52.1 5.6 25.0 8.6 9.7 7.4 96.7 38.8 40.7 45.8 31.9 28.2 0.1 50.6 43.7 60.2 44.4 24.3 51.1 31.7 7.8 27.1 8.8 40.3 23.3 43.7 4.1 22.2 10.6 28.0 40.9 82.5 49.7 50.7 6.6 4.3 0.5 23.4 7.8 4.2 5.8 12.5 30.1 31.7 0.1 23.2 5.0 111.8 25.5 21.2 22.9 66.3 54.3 14.7 7.2 22.8 12.5 175.3 39.0 52.8 33.7 78.2 0.3 6.3 0.2 35.3 23.4 24.6 0.2 4.5 0.0 0.1 4.5 0.0 0.0 0.0 0.2 3.8 0.0 0.2 0.1 1.1 0.7 5.5 0.5 0.0 1.7 10.2 9.1 9.0 10.0 9.0 16.6 9.7 11.0 12.4 7.4 14.9 7.9 11.1 16.0 25.2 2.3 1.6 3.6 16.0 6.9 4.0 5.7 4.7 3.4 14.4 14.3 12.2 1.8 2.1 2.9 0.2 18.5 3.9 37.9 10.5 5.4 6.3 20.4 13.1 2.1 11.4 35.3 34.8 7.7 13.7 11.6 1.3 6.5 7.9 41.1 8.4 1.7 13.7 11.3 2.0 8.9 7.5 14.3 5.6 6.8 1.8 5.6 17.2 1.8 2.1 6.0 4.6 69.6 18.0 15.8 0.2 14.4 10.8 5.7 2.8 3.4 0.0 23.8 10.4 10.4 1.5 5.8 5.5 1.0 0.9 10.8 12.7 7.4 PWWP2A KIAA1935 ENSG00000170234 "PWWP domain containing 2A" Q96N64 5 160061801-160119450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046733, HPA058233" Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Focal adhesion sites" "HPA046733: AB_2679777, HPA058233: AB_2683647" "unprognostic (1.03e-1)" "unprognostic (2.67e-1)" "unprognostic (5.13e-2)" "unprognostic (1.85e-1)" "unprognostic (1.18e-2)" "unprognostic (7.86e-3)" "unprognostic (1.40e-3)" "unprognostic (6.24e-2)" "unprognostic (2.42e-2)" "unprognostic (7.08e-2)" "unprognostic (7.25e-2)" "unprognostic (8.24e-3)" "prognostic unfavorable (3.70e-4)" "unprognostic (2.23e-1)" "unprognostic (3.88e-2)" "unprognostic (1.08e-1)" "prognostic favorable (3.51e-4)" 6.7 7.0 9.6 7.4 14.8 10.3 6.8 22.8 10.9 10.3 8.2 10.5 7.5 7.9 5.3 6.6 7.6 6.2 5.9 7.8 8.6 8.5 7.1 7.6 10.1 12.2 12.2 7.6 8.0 5.9 8.1 8.7 11.9 8.6 10.8 14.2 7.1 6.0 6.1 11.3 8.5 7.0 9.5 9.4 9.3 5.1 11.6 12.4 7.2 6.0 9.0 8.2 7.9 24.2 13.4 6.3 16.1 13.7 17.5 13.6 22.5 10.4 8.4 9.1 9.1 20.5 25.3 21.4 15.6 8.0 14.9 9.4 14.1 16.2 14.8 22.3 15.6 15.4 11.9 10.6 13.3 15.6 11.2 9.7 7.9 18.3 13.8 20.4 14.8 11.9 12.0 13.5 15.5 11.1 13.5 15.1 19.0 11.3 8.1 20.9 14.3 13.7 11.2 9.4 18.8 13.1 17.6 17.3 19.4 12.9 13.4 17.1 19.9 15.7 10.9 11.9 20.6 15.4 14.7 18.9 10.4 15.6 15.9 3.2 2.0 1.1 1.1 0.9 0.9 3.3 1.2 1.4 1.3 1.6 2.0 1.1 2.1 0.4 1.2 1.2 1.2 0.4 9.6 14.8 22.8 10.9 7.8 8.6 12.2 12.2 11.9 9.5 11.6 24.2 16.8 9.6 22.7 42.7 25.0 31.9 13.0 10.8 27.3 102.0 15.8 13.2 13.9 11.5 15.6 20.2 73.0 12.3 22.0 30.2 17.6 13.7 2.1 18.2 33.8 18.7 32.9 30.3 47.2 11.0 12.4 20.4 20.9 17.3 23.5 29.0 18.2 8.8 9.2 94.2 61.8 25.9 20.3 13.7 17.6 3.8 55.9 16.9 10.6 52.5 25.7 28.8 22.6 92.0 228.5 16.5 17.8 38.4 19.5 19.4 11.2 7.2 14.4 57.6 26.3 23.5 25.1 20.4 22.0 18.3 25.9 9.3 23.8 34.0 25.2 11.2 PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.1;Endometrial stromal cells: 99.4;Endothelial cells: 95.1;Hepatic stellate cells: 71.4;Skeletal myocytes: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 323.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA012375 Approved "Secreted to extracellular matrix" NA NA 9100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA012375: AB_1855965" "unprognostic (4.37e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (8.16e-3)" "unprognostic (1.91e-1)" "unprognostic (1.92e-2)" "unprognostic (3.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.34e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.18e-1)" "unprognostic (7.33e-3)" "unprognostic (5.54e-3)" 59.5 5.5 4.1 24.3 3.5 0.9 33.7 1.9 4.1 18.2 27.5 36.1 7.9 32.8 4.0 4.9 18.0 22.7 22.7 3.1 7.7 9.0 12.4 27.6 5.0 4.2 6.2 32.7 3.8 3.0 11.7 33.4 4.7 17.5 8.7 5.2 13.6 11.1 7.7 6.9 16.3 61.8 2.6 10.0 13.2 6.4 5.2 2.1 8.4 11.5 2.1 33.8 13.5 3.4 39.9 13.9 72.0 0.1 198.3 180.9 54.6 231.4 182.3 99.0 107.9 0.1 0.5 0.0 323.8 230.3 4.5 8.3 0.3 142.3 125.5 0.6 2.4 0.0 139.3 0.0 196.4 0.6 0.0 200.7 41.0 112.2 83.8 299.5 247.0 35.9 0.1 0.0 142.6 23.6 6.8 8.0 58.3 0.0 52.3 13.2 250.8 0.6 115.9 0.1 0.2 131.9 0.2 73.6 0.4 142.9 27.0 0.9 242.4 162.8 79.7 6.2 180.7 0.2 205.4 1.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.1 3.5 1.9 4.1 3.1 7.7 4.2 6.2 4.7 2.6 5.2 3.4 79.1 6.4 2.3 2.6 0.4 2.9 2.8 12.8 0.6 2.5 17.5 14.1 5.8 17.2 7.0 1.8 0.0 0.6 0.2 0.3 0.0 10.4 33.4 4.2 99.4 95.1 1.8 0.0 6.6 0.0 11.3 45.2 0.0 3.4 1.3 43.7 71.4 1.8 1.9 0.0 7.3 1.3 20.3 5.7 4.4 40.7 26.8 0.7 7.2 8.4 0.6 10.0 1.0 55.8 0.7 0.5 0.1 15.1 0.0 14.0 0.0 0.2 6.7 0.8 46.0 120.1 51.1 22.0 16.0 0.5 2.8 1.4 1.0 33.3 0.5 1.4 PXDNL "FLJ25471, PMR1" ENSG00000147485 "Peroxidasin like" A1KZ92 8 51319577-51809445 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrogen peroxide" "Endonuclease, Hydrolase, Nuclease, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 45.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 42.2;Early spermatids: 43.8;Excitatory neurons: 25.2;Inhibitory neurons: 68.8;Microglial cells: 16.9;Muller glia cells: 18.6;Spermatocytes: 24.2" "Group enriched" "Detected in some" 4 "breast cancer: 1.7;glioma: 0.7;renal cancer: 0.8;testis cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 7.7;Daudi: 5.9;SH-SY5Y: 6.1" HPA007919 Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA007919: AB_1855966" "prognostic unfavorable (3.27e-5)" "unprognostic (4.59e-4)" "unprognostic (5.57e-3)" "unprognostic (2.83e-3)" "unprognostic (2.71e-1)" "unprognostic (5.14e-2)" "unprognostic (1.18e-1)" "unprognostic (7.18e-3)" "unprognostic (1.85e-1)" "unprognostic (1.15e-1)" "unprognostic (7.07e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-4)" "unprognostic (2.28e-2)" "unprognostic (3.35e-2)" "unprognostic (2.42e-2)" "unprognostic (2.97e-4)" 1.6 0.1 0.2 0.2 0.1 0.0 0.2 0.2 0.6 0.1 0.0 0.1 0.0 0.1 9.4 0.2 0.0 0.1 45.3 0.2 0.3 1.6 0.0 0.2 0.3 0.5 0.6 0.1 0.0 0.2 0.0 0.0 0.8 0.2 0.1 2.9 0.3 0.0 1.4 0.2 0.2 0.0 0.1 0.4 0.0 5.0 0.2 0.5 0.3 2.1 0.5 0.0 0.0 0.4 0.5 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.6 0.2 0.3 0.5 0.6 0.8 0.1 0.2 0.4 0.3 0.0 0.0 10.7 0.0 0.1 0.1 0.0 0.0 1.2 3.7 0.1 42.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.9 0.0 43.8 0.0 0.0 0.3 0.0 0.0 25.2 0.0 0.0 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 68.8 0.0 0.0 0.0 0.0 6.3 0.0 0.1 0.0 16.9 0.0 18.6 0.0 14.1 14.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.2 0.8 24.2 1.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 PXYLP1 "ACPL2, FLJ23751" ENSG00000155893 "2-phosphoxylose phosphatase 1" Q8TE99 3 141228726-141367753 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 148.2" "Cell type enhanced" "Detected in many" "Early spermatids: 196.8;Late spermatids: 131.1;Spermatocytes: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017243 Uncertain "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA017243: AB_1844509" "unprognostic (9.55e-2)" "unprognostic (3.48e-3)" "unprognostic (1.81e-1)" "unprognostic (2.06e-1)" "unprognostic (8.45e-2)" "unprognostic (8.04e-3)" "unprognostic (4.05e-3)" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (6.95e-2)" "unprognostic (5.07e-3)" "unprognostic (4.67e-2)" "unprognostic (1.29e-2)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (8.56e-2)" "unprognostic (8.17e-3)" 4.2 6.3 5.6 4.3 6.4 5.0 8.3 1.7 13.5 7.3 0.3 5.4 5.5 8.8 148.2 2.6 6.4 8.2 13.8 6.3 6.5 7.5 5.1 4.9 9.1 1.0 3.0 8.6 9.2 16.2 7.4 18.2 1.1 10.1 5.6 18.3 6.6 28.9 2.9 4.6 6.4 7.2 3.4 5.3 5.0 8.9 3.4 53.3 5.9 2.0 9.9 7.0 4.7 6.6 5.3 5.5 23.3 18.5 9.0 7.7 5.6 3.6 9.0 9.1 12.5 9.2 1.8 0.3 4.9 8.2 1.9 1.2 24.7 2.3 8.7 17.4 16.3 1.9 7.5 7.4 19.2 4.8 1.0 7.3 10.4 2.8 1.0 11.3 0.6 17.8 0.9 2.1 4.1 4.5 25.8 6.0 9.7 13.2 3.1 3.5 13.6 3.2 6.5 22.8 10.1 17.8 9.3 2.9 7.6 4.2 9.7 2.8 1.1 11.6 6.9 8.0 3.5 4.9 0.4 0.7 10.7 6.5 10.4 15.2 6.0 9.4 13.4 4.0 8.6 0.7 7.5 8.9 5.3 0.5 21.6 17.6 3.8 19.3 2.0 1.9 4.3 8.9 5.6 6.4 1.7 13.5 6.3 6.5 1.0 3.0 1.1 3.4 3.4 6.6 1.1 9.6 8.7 14.0 2.2 0.0 4.6 0.0 6.2 3.3 9.5 6.7 7.6 2.8 1.8 46.0 6.2 2.1 3.4 2.1 0.0 3.2 196.8 1.0 9.3 1.4 4.2 4.4 41.3 3.7 8.2 7.9 1.1 1.8 2.5 5.4 1.4 3.8 0.7 6.7 31.8 3.9 0.0 1.8 0.0 131.1 20.2 2.0 0.0 1.0 3.5 8.0 3.1 32.6 6.5 3.0 8.6 15.1 2.7 7.6 4.2 11.7 2.9 5.2 13.1 6.6 4.2 95.9 13.8 2.2 0.0 1.1 4.9 0.9 4.7 6.6 PYROXD1 "DKFZp762G094, FLJ22028" ENSG00000121350 "Pyridine nucleotide-disulphide oxidoreductase domain 1" Q8WU10 12 21437615-21471250 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Oxidoreductase "Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038319, HPA038320" Uncertain Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA038319: AB_10669522, HPA038320: AB_2675956" "unprognostic (1.48e-1)" "unprognostic (1.68e-1)" "unprognostic (1.15e-2)" "unprognostic (9.89e-2)" "unprognostic (1.51e-1)" "unprognostic (2.64e-3)" "unprognostic (1.50e-1)" "unprognostic (9.31e-2)" "unprognostic (8.94e-3)" "unprognostic (1.17e-2)" "unprognostic (1.57e-1)" "unprognostic (3.32e-2)" "unprognostic (1.06e-2)" "unprognostic (3.78e-2)" "unprognostic (2.30e-2)" "unprognostic (2.00e-1)" "prognostic favorable (1.70e-4)" 7.9 10.0 3.8 9.2 4.3 9.3 10.4 5.1 5.4 7.1 5.3 11.9 13.9 7.1 8.6 8.3 7.1 8.7 10.7 3.7 5.2 16.8 12.3 8.6 10.6 5.4 5.2 6.6 13.4 10.4 5.2 5.9 5.3 9.9 11.2 14.0 11.9 5.9 12.4 10.0 16.0 6.4 4.7 7.9 12.8 5.8 4.2 7.5 15.6 9.6 8.5 7.6 6.1 5.4 9.3 3.5 5.2 5.8 3.7 6.8 11.8 14.5 6.7 5.2 4.0 4.5 8.6 10.2 6.0 11.0 4.4 11.3 5.8 11.4 5.8 12.1 5.1 11.8 9.2 5.7 17.2 17.7 12.0 11.3 13.5 3.3 14.3 6.7 7.8 11.0 5.8 4.2 10.7 5.9 8.3 24.3 8.6 8.2 6.5 1.4 11.2 11.2 16.3 9.2 1.7 13.1 6.7 12.2 27.0 7.1 14.5 20.8 11.2 6.2 5.9 13.5 13.4 6.4 4.8 12.7 25.4 13.1 7.5 1.2 0.8 0.6 1.7 1.5 1.9 1.2 2.0 2.1 0.8 0.9 1.6 1.7 0.3 1.6 2.7 1.1 1.6 0.9 3.8 4.3 5.1 5.4 3.7 5.2 5.4 5.2 5.3 4.7 4.2 5.4 12.5 12.8 28.4 12.7 18.3 6.6 10.2 10.7 8.0 21.8 15.1 10.8 11.7 27.1 13.6 27.6 25.0 15.4 22.9 40.0 23.5 24.7 179.8 26.0 13.0 9.4 20.4 13.3 14.0 33.4 14.2 10.4 19.9 21.1 25.3 8.6 8.9 21.2 16.2 8.4 17.0 21.3 12.2 21.8 5.8 32.6 10.5 18.1 5.4 17.8 15.6 14.5 17.5 13.0 34.2 41.2 25.1 6.4 19.5 12.0 39.4 43.8 28.6 28.2 13.1 15.0 13.8 49.7 18.8 14.5 7.7 19.4 20.1 10.6 20.6 14.1 PYY PYY1 ENSG00000131096 "Peptide YY" P10082 17 43952738-44004469 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "intestine: 52.5" "Cell type enriched" "Detected in some" 96 "Enteroendocrine cells: 19377.2" "Group enriched" "Detected in many" 8 "endometrial cancer: 7.9;ovarian cancer: 15.2;testis cancer: 18.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 2.9" "Region enriched" "Detected in single" 14 "pons and medulla: 1.4" "Low region specificity" "Detected in single" "HPA010973, CAB016734" Enhanced "Secreted to blood" NA NA 87100 "Cluster 9: Intestine - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB016734: AB_876471, HPA010973: AB_1855194" "unprognostic (8.17e-3)" "unprognostic (5.41e-2)" "unprognostic (9.93e-2)" "unprognostic (1.81e-3)" "unprognostic (2.48e-4)" "unprognostic (5.26e-2)" "unprognostic (4.14e-2)" "unprognostic (1.80e-2)" "unprognostic (1.75e-2)" "unprognostic (1.54e-2)" "unprognostic (2.91e-1)" "unprognostic (1.29e-1)" "unprognostic (5.69e-3)" "unprognostic (3.77e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-1)" "unprognostic (1.20e-1)" 0.1 1.7 0.2 1.4 0.3 0.1 0.4 0.2 0.7 0.3 0.1 52.5 2.5 0.4 0.4 0.0 0.4 0.0 0.0 0.3 0.3 1.4 0.2 0.2 0.3 0.3 0.3 0.0 0.6 0.2 0.0 0.0 0.4 0.3 36.6 0.8 0.1 0.8 0.1 0.1 41.6 0.1 0.1 0.1 0.5 1.1 0.4 0.3 0.5 0.1 0.1 0.0 0.0 0.5 0.1 0.2 0.2 0.4 0.3 0.6 0.0 0.4 0.1 0.5 0.3 0.5 0.3 0.2 0.6 0.5 0.4 0.2 0.4 0.1 0.3 1.2 0.2 0.7 0.2 0.0 0.4 0.2 2.9 0.8 0.1 0.5 0.2 0.6 0.1 0.3 0.2 0.5 0.4 0.6 0.2 0.4 0.6 0.4 0.2 0.1 0.1 0.0 0.8 0.0 0.4 0.1 0.3 0.0 0.7 0.3 0.5 0.0 0.5 0.6 0.5 0.1 0.4 0.0 0.5 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.7 0.3 0.3 0.3 0.3 0.4 0.1 0.4 0.5 0.1 0.0 0.0 0.3 1.4 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 65.0 1.9 0.0 1.0 7.9 1.3 0.1 19377.2 0.0 3.5 0.0 0.1 0.0 0.0 18.9 8.9 0.1 0.0 0.0 0.0 0.0 3.3 199.9 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 35.5 0.0 0.0 0.0 20.7 0.1 0.0 0.0 0.0 0.0 0.1 2.3 4.3 0.0 0.1 0.0 1.0 0.0 36.8 0.0 PZP CPAMD6 ENSG00000126838 "PZP alpha-2-macroglobulin like" P20742 12 9148840-9208395 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 81.6" "Group enriched" "Detected in some" 4 "Early spermatids: 26.2;Hepatocytes: 26.4;Late spermatids: 11.0;Oligodendrocyte precursor cells: 8.5;Respiratory ciliated cells: 24.7" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.0;liver cancer: 0.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.1;MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Group enriched" "Detected in some" 9 "HeLa: 5.7;SiHa: 2.5" "HPA041403, HPA041471" Supported "Secreted to blood" NA NA 15000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA041403: AB_10804003, HPA041471: AB_10795636" "unprognostic (8.48e-3)" "unprognostic (1.12e-2)" "unprognostic (2.28e-1)" "unprognostic (8.54e-4)" "unprognostic (4.79e-1)" "unprognostic (3.50e-2)" "unprognostic (2.04e-4)" "unprognostic (4.57e-2)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (9.71e-2)" "unprognostic (4.95e-2)" "unprognostic (1.08e-5)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-2)" "unprognostic (9.81e-3)" 0.2 0.0 0.4 0.0 1.3 0.1 0.2 0.9 0.6 0.2 0.6 0.0 0.0 1.3 0.1 0.0 1.2 0.0 0.7 0.9 0.6 0.2 81.6 0.8 0.0 2.3 6.7 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 0.6 0.0 2.3 1.0 0.0 0.1 0.1 0.0 0.1 0.1 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 1.1 0.0 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.9 0.6 0.9 0.6 2.3 6.7 3.9 0.9 1.0 1.3 1.9 3.2 0.0 3.3 0.1 0.0 0.0 0.6 0.0 0.8 0.0 0.0 1.6 0.0 2.7 0.0 2.1 0.0 1.4 0.0 0.0 0.0 26.2 4.7 0.2 2.1 0.0 0.0 3.7 0.0 0.0 0.1 0.0 1.7 0.0 0.0 1.8 26.4 0.0 0.0 2.9 0.0 0.0 0.3 0.0 11.0 0.0 0.2 0.0 2.8 0.0 0.0 2.1 8.5 4.6 0.0 0.0 0.4 0.7 0.0 0.0 0.0 24.7 0.6 0.0 0.3 0.4 0.5 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37342827-37373322 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 170.3;epididymis: 104.0" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 217.0;Ionocytes: 138.4;Langerhans cells: 163.4;Melanocytes: 528.3" "Cancer enhanced" "Detected in all" "melanoma: 97.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 1527.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 1527.7" "Cell line enhanced" "Detected in many" "SCLC-21H: 117.1;SK-MEL-30: 426.8;U-266/84: 341.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" NA NA 390000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA008406: AB_1855981" "unprognostic (6.25e-3)" "unprognostic (6.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-3)" "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.78e-2)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (9.48e-3)" "unprognostic (3.62e-3)" 5.6 170.3 8.4 14.2 7.5 47.3 15.8 5.1 11.5 21.2 4.2 25.3 5.6 9.8 104.0 3.4 2.2 10.8 5.1 8.9 27.4 6.1 2.6 5.6 8.1 9.7 11.6 1.0 13.7 14.8 27.0 9.2 14.7 7.2 10.2 11.9 25.5 6.7 4.1 36.3 4.5 8.3 7.8 13.9 7.6 2.0 20.3 5.1 3.8 2.8 12.5 15.2 4.6 6.7 1.0 40.7 0.1 0.0 6.0 13.3 0.1 6.6 86.5 6.4 10.1 2.9 7.1 0.2 3.0 32.6 72.9 0.1 2.7 0.6 10.3 0.6 76.0 18.7 0.3 7.7 0.6 3.0 0.1 8.5 0.0 47.3 0.2 0.4 26.2 0.0 0.0 0.0 0.2 4.5 0.0 1.7 0.6 0.3 0.0 0.0 0.0 0.8 42.6 10.9 117.1 0.2 6.4 1.4 426.8 8.0 0.7 2.9 19.4 0.0 0.2 0.1 0.6 15.3 341.7 0.3 25.8 0.3 0.0 9.8 344.8 3.2 0.4 38.7 1.0 2.6 0.6 0.5 124.7 1.2 0.5 0.3 1527.7 0.2 3.3 2.4 0.1 169.8 8.4 7.5 5.1 11.5 8.9 27.4 9.7 11.6 14.7 7.8 20.3 6.7 1.8 3.2 2.3 0.3 12.5 39.0 13.6 40.0 2.2 21.8 7.9 8.5 1.1 1.5 17.7 22.0 2.1 0.7 0.8 6.1 1.9 45.4 0.6 2.6 24.7 17.5 217.0 1.7 8.5 2.4 6.1 26.7 3.1 4.0 55.3 1.6 22.5 0.3 20.5 43.7 7.3 6.6 138.4 21.2 163.4 2.9 3.1 26.8 528.3 6.5 64.3 0.8 3.1 3.0 1.3 31.8 1.8 23.7 26.0 9.1 0.2 11.7 4.3 3.2 13.1 0.6 6.6 1.7 0.7 0.6 14.5 4.7 5.6 5.0 7.3 5.8 QPCTL FLJ20084 ENSG00000011478 "Glutaminyl-peptide cyclotransferase like" Q9NXS2 19 45692403-45703989 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 5.5;granulocytes: 5.7;Inhibitory neurons: 6.5;Plasma cells: 9.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040797 Approved Supported "Golgi apparatus" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA040797: AB_10794148" "unprognostic (6.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.09e-1)" "unprognostic (7.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.26e-1)" "unprognostic (8.41e-3)" "unprognostic (2.30e-2)" "unprognostic (9.46e-2)" "unprognostic (1.69e-1)" "unprognostic (3.14e-2)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.15e-8)" "unprognostic (1.07e-1)" "unprognostic (1.75e-1)" "unprognostic (4.02e-2)" "unprognostic (5.71e-2)" 4.1 7.8 3.9 3.1 3.9 4.1 4.9 3.6 4.8 4.9 4.1 5.9 4.7 4.8 3.7 4.7 4.8 2.5 3.4 4.2 4.0 5.3 9.2 6.2 4.7 4.5 3.8 6.6 7.5 4.4 7.0 3.7 4.5 6.5 3.9 2.1 6.7 3.4 1.5 5.2 5.5 2.5 3.2 8.5 6.1 4.4 4.2 2.4 6.7 0.8 3.5 4.6 4.4 3.9 16.7 10.8 8.5 36.9 8.6 4.1 6.4 10.3 15.7 15.0 24.7 11.2 12.3 19.7 11.1 11.5 15.4 9.5 10.0 11.9 8.9 5.0 12.7 6.7 10.9 24.6 14.6 7.5 12.0 7.6 14.9 12.6 17.3 10.7 13.6 10.8 9.7 32.1 9.5 13.0 7.0 7.7 5.5 14.2 5.4 7.8 6.4 16.5 16.2 8.0 7.6 4.7 10.6 8.8 18.2 3.7 6.4 10.6 8.4 7.4 12.4 7.3 10.4 28.6 20.2 18.2 26.0 17.2 5.8 1.4 0.3 0.2 1.4 0.5 0.9 0.9 0.6 0.3 0.8 0.6 0.5 0.7 1.3 1.4 0.3 1.0 0.3 0.2 3.9 3.9 3.6 4.8 4.2 4.0 4.5 3.8 4.5 3.2 4.2 3.9 0.5 0.0 1.5 2.3 3.3 1.3 1.2 1.1 0.6 1.1 0.7 0.6 0.8 1.5 1.2 0.0 0.0 0.8 2.1 1.2 0.0 0.6 5.4 0.9 1.4 0.7 0.0 1.3 5.5 0.4 1.4 0.7 1.5 1.4 5.7 0.7 0.0 1.3 0.9 1.7 6.5 0.4 0.0 0.6 1.8 1.3 0.0 1.6 1.8 0.0 0.7 0.3 1.0 3.5 1.6 0.6 0.1 0.0 9.8 1.2 0.7 0.1 2.2 2.4 0.0 0.6 1.1 1.0 0.3 1.4 1.1 0.8 2.4 1.5 1.0 0.5 QPRT QPRTase ENSG00000103485 "Quinolinate phosphoribosyltransferase" Q15274 16 29663279-29698699 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 119.4;liver: 183.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 404.7;Extravillous trophoblasts: 315.1;Hepatocytes: 367.4;Proximal tubular cells: 598.8;Syncytiotrophoblasts: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 4.2;intermediate monocyte: 5.3;myeloid DC: 5.8;non-classical monocyte: 9.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 8 "dendritic cells: 5.8;monocytes: 9.0" "Cell line enhanced" "Detected in many" "EFO-21: 597.1;Hep G2: 258.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011887, HPA076010" Enhanced Approved Vesicles "Intracellular and membrane" NA NA 780000 "Cluster 7: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA011887: AB_2668555, HPA076010: " "prognostic unfavorable (5.10e-5)" "unprognostic (2.00e-1)" "unprognostic (9.48e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (9.31e-4)" "unprognostic (1.44e-2)" "unprognostic (8.75e-2)" "unprognostic (1.22e-1)" "unprognostic (8.16e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (6.81e-2)" "unprognostic (3.37e-2)" "unprognostic (1.33e-2)" "unprognostic (2.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.58e-2)" 8.4 89.4 20.6 4.3 20.2 4.8 6.7 25.8 19.8 50.6 19.4 19.2 61.6 26.1 95.2 4.0 43.6 10.2 26.8 18.5 22.2 119.4 183.5 9.2 6.8 28.6 26.6 31.0 34.5 16.2 5.8 27.3 32.4 7.0 15.2 7.5 13.4 26.1 5.1 5.1 30.3 13.7 23.6 17.2 7.1 4.1 22.8 8.2 6.5 1.2 5.2 10.5 11.5 23.3 0.6 1.4 51.8 56.4 8.8 21.6 167.8 6.0 5.2 8.6 11.0 145.9 91.9 2.3 597.1 10.8 10.0 1.0 18.5 0.6 4.5 0.8 16.7 27.1 2.2 258.0 52.5 4.1 10.4 69.8 1.4 4.8 0.2 12.8 0.2 28.2 75.1 2.9 0.4 154.6 17.6 100.3 162.1 1.9 0.2 89.3 16.3 58.5 47.9 4.2 48.6 103.5 0.0 142.1 118.8 85.1 106.5 112.8 0.6 2.5 24.9 0.9 0.5 1.8 4.9 18.8 4.4 10.4 8.1 0.0 4.2 0.3 0.8 5.3 0.9 0.1 0.6 0.7 5.8 0.0 0.1 0.4 0.8 0.4 9.0 3.1 0.9 1.9 20.6 20.2 25.8 19.8 18.5 22.2 28.6 26.6 32.4 23.6 22.8 23.3 3.1 9.6 24.8 5.2 10.1 3.6 11.7 0.5 1.8 3.3 5.0 2.0 43.2 8.6 3.0 64.4 0.0 404.7 5.8 84.5 50.9 1.2 0.0 93.8 49.5 5.5 28.3 10.5 1.3 55.2 315.1 35.8 0.5 81.0 5.1 6.7 9.7 367.4 147.5 6.7 5.6 47.3 0.0 21.2 18.3 0.5 29.2 19.8 42.7 12.2 4.4 20.8 3.1 11.1 0.5 11.5 78.5 27.1 8.7 4.2 161.0 598.8 1.5 5.0 6.6 3.3 16.2 0.5 3.0 0.2 2.0 215.6 5.7 36.5 104.7 8.3 QRFP "26RFa, P518" ENSG00000188710 "Pyroglutamylated RFamide peptide" P83859 9 130892707-130896812 "Predicted secreted proteins" Neuropeptide "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 1.1;Bipolar cells: 1.0;Rod photoreceptor cells: 1.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.0" "Lineage enriched" "Detected in single" 11 "monocytes: 1.0" "Cell line enhanced" "Detected in some" "U-138 MG: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043377 Uncertain "Secreted in other tissues" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "HPA043377: AB_10959754" "unprognostic (1.79e-3)" "unprognostic (1.01e-1)" "unprognostic (2.28e-3)" "unprognostic (4.14e-3)" "unprognostic (7.78e-2)" "unprognostic (1.52e-1)" "unprognostic (5.67e-3)" "unprognostic (5.11e-3)" "unprognostic (1.77e-1)" "unprognostic (2.28e-1)" "unprognostic (5.43e-3)" "unprognostic (1.02e-1)" "unprognostic (2.52e-2)" "unprognostic (2.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.65e-1)" "unprognostic (7.04e-3)" 0.8 0.2 0.2 0.2 0.4 0.2 0.4 0.3 0.3 0.8 0.2 2.2 0.2 0.7 0.0 1.1 0.5 0.3 0.6 0.2 0.1 0.6 0.2 0.5 0.1 0.2 0.2 0.6 1.3 0.0 1.0 0.1 0.3 1.2 0.0 0.1 0.3 0.0 0.2 0.4 0.9 0.0 0.0 0.3 1.0 1.2 0.4 0.0 0.7 0.0 0.0 1.9 0.7 0.3 0.6 0.3 0.2 1.6 0.0 0.0 0.8 0.6 0.0 0.0 0.0 1.0 0.4 0.2 0.2 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.5 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.3 0.0 0.0 2.2 0.2 1.5 1.4 0.2 0.2 1.5 0.9 0.6 0.0 0.5 0.5 0.7 0.5 0.2 0.7 0.4 0.8 0.5 0.2 3.5 0.9 1.4 1.7 0.1 0.6 0.7 0.6 0.4 1.8 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.4 0.3 0.3 0.2 0.1 0.2 0.2 0.3 0.0 0.4 0.3 0.0 3.2 1.1 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 1616.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1918.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 2600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA056243: AB_2683077" "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" 84.8 84.9 35.8 52.1 39.4 115.5 53.2 42.7 47.3 81.7 41.1 100.1 67.5 75.2 70.2 178.4 82.3 150.3 244.9 41.5 43.4 73.8 81.7 200.0 16.3 50.0 40.7 196.1 136.3 21.0 60.2 158.9 43.2 92.3 80.9 15.2 105.6 57.5 91.2 58.6 85.7 60.0 44.0 61.9 178.3 172.9 42.6 12.1 31.9 46.0 19.6 174.1 108.7 57.7 441.4 62.0 14.8 181.0 179.1 367.8 712.5 456.5 456.6 381.6 267.1 7.3 137.7 6.8 276.7 367.8 52.6 93.7 17.6 123.5 185.0 26.4 28.0 14.1 33.6 19.4 1918.6 48.6 129.2 197.9 55.5 408.0 484.3 499.9 569.4 32.1 20.2 66.3 255.3 76.4 10.4 89.7 49.4 302.6 174.6 19.7 33.0 11.8 63.1 123.6 51.9 52.6 133.8 179.8 91.9 32.2 33.0 226.3 678.3 473.8 187.5 322.0 392.9 48.3 84.4 12.2 180.9 153.9 146.0 16.2 53.1 20.6 14.0 29.9 10.2 5.4 9.1 9.6 39.2 3.2 8.1 8.0 40.2 16.9 28.6 8.0 11.5 28.6 35.8 39.4 42.7 47.3 41.5 43.4 50.0 40.7 43.2 44.0 42.6 57.7 36.6 57.7 101.6 8.5 7.7 13.8 27.4 81.2 7.4 11.5 86.2 47.9 48.3 51.5 112.5 71.7 25.0 19.5 10.7 138.1 0.0 230.4 49.2 49.2 19.4 41.7 46.2 6.9 17.2 130.1 1616.7 78.0 136.6 80.4 25.4 27.1 89.3 4.3 68.6 6.7 17.0 185.7 132.2 45.2 35.3 20.1 177.7 48.9 44.4 8.4 49.7 53.5 10.3 24.6 23.9 249.8 165.6 71.1 12.8 35.7 9.0 9.1 47.8 6.7 32.9 13.6 31.3 30.2 32.7 10.2 9.9 154.3 13.9 13.9 89.9 68.0 R3HCC1 DKFZp564N123 ENSG00000104679 "R3H domain and coiled-coil containing 1" Q9Y3T6 8 23270120-23296279 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 113.2;Rod photoreceptor cells: 115.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023073, HPA023153" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 54: Non-specific - Microtubule organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Nucleoplasm "HPA023073: AB_1855987, HPA023153: AB_2237834" "unprognostic (5.80e-2)" "unprognostic (4.70e-3)" "prognostic favorable (4.08e-4)" "unprognostic (7.46e-3)" "unprognostic (1.97e-1)" "unprognostic (7.26e-2)" "unprognostic (8.49e-3)" "unprognostic (1.02e-2)" "unprognostic (7.73e-2)" "unprognostic (2.92e-1)" "prognostic favorable (8.66e-4)" "unprognostic (7.65e-2)" "prognostic favorable (6.80e-5)" "unprognostic (1.22e-2)" "unprognostic (1.17e-1)" "unprognostic (4.18e-1)" "unprognostic (3.43e-1)" 20.5 21.9 41.2 15.2 52.7 29.0 19.6 53.7 43.8 23.4 36.4 33.6 19.7 23.9 14.8 16.1 22.5 16.2 33.1 39.9 42.3 20.1 28.2 16.7 22.5 60.9 49.8 27.2 42.8 29.0 22.6 13.7 63.6 22.7 15.3 62.7 35.7 19.9 54.5 22.5 20.4 22.2 49.3 20.2 28.4 30.8 48.6 20.3 17.6 31.5 18.8 22.2 17.8 73.7 38.2 48.7 36.7 35.9 15.2 20.6 25.2 24.7 23.4 41.0 29.7 35.0 17.6 38.1 25.6 30.2 28.0 28.3 38.9 45.8 27.5 24.7 41.6 35.7 33.4 29.2 36.0 24.7 25.6 24.8 35.5 35.0 16.4 30.1 31.7 42.9 41.8 31.0 24.3 33.1 55.6 43.8 29.8 40.4 35.8 37.9 44.8 22.8 20.3 41.9 47.2 41.1 28.1 32.8 41.8 25.0 30.3 29.2 27.4 37.9 31.8 32.2 51.1 23.8 22.2 39.3 29.5 34.3 48.5 38.4 50.5 82.5 64.8 44.1 56.5 56.5 52.7 55.0 56.7 42.1 40.5 47.0 31.3 59.5 50.3 52.9 61.5 51.4 41.2 52.7 53.7 43.8 39.9 42.3 60.9 49.8 63.6 49.3 48.6 73.7 25.2 25.6 14.7 4.9 15.5 14.9 16.5 35.9 10.2 28.0 22.8 32.9 24.1 24.3 20.5 5.5 27.1 18.8 19.8 17.9 56.7 32.3 36.4 15.2 17.0 21.1 19.2 17.9 5.1 50.9 21.3 25.4 20.9 10.2 22.8 24.7 20.0 21.6 30.2 18.5 5.0 21.5 22.4 18.2 12.3 113.2 17.7 16.2 21.4 5.6 18.8 59.3 42.2 4.5 9.5 37.0 22.1 21.8 34.7 11.4 41.7 38.5 22.0 115.7 13.1 19.9 31.1 49.8 32.4 13.6 16.2 7.7 18.3 30.7 22.8 13.6 R3HDM4 "C19orf22, MGC16353" ENSG00000198858 "R3H domain containing 4" Q96D70 19 896503-913245 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 586.7" "Lineage enriched" "Detected in all" 12 "granulocytes: 586.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043025, HPA048638" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "HPA043025: AB_2678275, HPA048638: AB_2680472" "unprognostic (9.22e-2)" "unprognostic (2.32e-2)" "unprognostic (1.28e-2)" "prognostic favorable (7.33e-6)" "unprognostic (4.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.94e-3)" "unprognostic (1.06e-1)" "unprognostic (3.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" "unprognostic (4.28e-1)" "unprognostic (1.46e-3)" "unprognostic (7.44e-2)" "unprognostic (4.52e-1)" "unprognostic (2.08e-1)" "unprognostic (6.74e-2)" 37.7 26.3 34.5 50.1 31.2 98.0 37.0 33.7 38.5 42.0 29.3 39.4 23.9 34.1 13.4 81.8 36.9 28.4 32.4 32.1 28.0 58.8 47.8 55.7 54.3 31.3 29.4 23.7 50.8 19.2 33.1 25.1 28.9 42.2 17.5 22.0 48.1 15.8 55.8 58.8 45.5 18.7 25.6 93.9 39.1 9.1 29.7 39.6 32.4 23.8 36.5 43.2 49.4 37.0 44.2 25.4 26.1 36.5 16.6 28.9 43.7 29.3 23.2 28.8 25.4 27.6 36.7 31.5 23.9 33.4 6.1 39.6 15.4 34.7 12.9 49.2 33.0 43.7 19.7 48.3 49.3 24.6 73.0 38.7 65.9 18.7 39.1 26.3 33.4 35.7 82.2 62.8 27.1 79.0 34.7 46.5 34.5 53.3 41.2 33.9 12.5 60.8 48.2 45.7 46.6 45.4 25.8 56.2 48.9 20.0 49.1 57.8 34.3 52.3 29.1 62.0 30.0 69.1 39.1 47.6 33.5 34.9 45.9 117.4 13.1 111.0 14.9 10.1 23.1 38.5 30.3 20.5 14.3 21.5 28.1 20.1 586.7 8.6 14.0 6.0 49.3 26.5 34.5 31.2 33.7 38.5 32.1 28.0 31.3 29.4 28.9 25.6 29.7 37.0 23.2 19.2 21.5 0.7 59.6 35.1 49.0 24.9 25.0 17.5 30.7 20.6 6.8 20.0 26.3 18.4 8.4 38.1 29.0 34.7 7.9 57.7 1.3 20.1 20.1 22.8 32.8 106.5 4.0 55.4 46.7 20.0 30.5 33.5 23.5 10.3 12.1 13.3 26.2 28.6 3.0 31.3 34.6 27.5 37.0 2.6 11.1 59.0 24.9 1.9 51.4 8.0 29.9 1.5 3.1 68.4 31.9 11.7 37.3 48.9 13.1 16.0 19.9 12.4 26.3 13.6 20.6 0.8 4.0 34.3 31.7 69.0 48.1 15.2 22.6 70.9 R3HDML dJ881L22.3 ENSG00000101074 "R3H domain containing like" Q9H3Y0 20 44337043-44351238 "Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "intestine: 2.4" "Cell type enriched" "Detected in single" 5 "Microglial cells: 1.0" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.0;OE19: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA070264 Enhanced "Secreted - unknown location" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "HPA070264: AB_2686244" "unprognostic (1.89e-1)" "unprognostic (2.23e-1)" "unprognostic (9.86e-2)" "unprognostic (9.12e-2)" "unprognostic (6.06e-3)" "unprognostic (2.64e-1)" "unprognostic (6.32e-2)" "unprognostic (4.95e-3)" 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.7 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.4 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RAB12 ENSG00000206418 "RAB12, member RAS oncogene family" Q6IQ22 18 8609437-8639382 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 193.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 96.4;Inhibitory neurons: 46.3;Microglial cells: 45.9;Oligodendrocytes: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040727 Approved Approved Vesicles NA NA "Cluster 42: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA040727: AB_10794858" "unprognostic (7.92e-2)" "unprognostic (4.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-2)" "unprognostic (1.53e-2)" "unprognostic (1.47e-2)" "unprognostic (1.25e-2)" "unprognostic (2.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.29e-3)" "unprognostic (2.67e-1)" "unprognostic (5.72e-2)" "unprognostic (2.02e-1)" "unprognostic (1.63e-1)" "unprognostic (1.46e-1)" "unprognostic (1.61e-1)" "unprognostic (9.11e-2)" 36.8 26.2 27.0 17.8 29.8 13.6 27.9 31.6 33.9 28.3 21.6 34.9 11.8 29.7 19.6 28.8 26.7 18.5 85.4 30.0 31.3 31.4 36.5 30.3 20.9 25.3 27.3 31.0 13.4 21.7 21.3 30.0 25.8 22.7 16.9 22.6 18.0 29.7 193.8 31.5 20.2 34.3 28.3 28.0 19.2 12.0 32.7 15.2 19.8 106.6 20.8 29.0 25.3 27.2 33.1 19.4 22.1 23.2 64.3 54.2 12.2 44.0 60.2 49.1 57.4 26.3 29.7 11.3 41.7 53.1 36.8 20.6 25.7 47.1 59.3 4.5 20.8 9.7 20.7 27.7 59.5 12.8 9.8 53.9 65.2 36.3 45.9 50.6 60.2 10.0 15.0 15.8 48.2 35.9 14.8 12.9 14.3 113.8 18.0 10.2 53.6 10.9 48.5 43.8 36.5 25.8 33.6 45.1 57.6 31.0 13.2 19.5 50.6 56.6 33.0 57.2 67.7 10.6 6.6 9.8 42.4 11.8 37.0 4.5 0.9 1.0 0.8 1.5 1.1 1.3 0.9 0.9 0.7 1.1 1.1 1.1 1.6 1.5 2.4 1.7 1.0 0.5 27.0 29.8 31.6 33.9 30.0 31.3 25.3 27.3 25.8 28.3 32.7 27.2 34.1 12.8 19.3 31.6 3.8 6.5 1.7 1.9 2.8 15.1 11.6 12.2 96.4 1.5 8.3 3.7 6.2 1.8 7.1 1.6 3.9 2.3 0.0 8.1 14.1 16.1 5.4 3.2 41.6 1.3 1.4 14.5 4.6 7.6 6.3 9.4 16.4 16.0 1.7 11.8 46.3 2.5 2.0 16.6 12.3 0.4 3.4 9.3 3.6 45.9 4.5 14.1 2.1 23.6 43.3 3.2 1.7 4.5 2.4 6.3 2.2 5.9 7.0 7.7 0.0 13.2 13.6 1.0 1.5 4.5 8.4 1.1 4.5 12.3 3.1 4.5 RAB26 ENSG00000167964 "RAB26, member RAS oncogene family" Q9ULW5 16 2140803-2154165 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.9;choroid plexus: 43.0;liver: 45.9;pancreas: 42.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 36.1;Enteroendocrine cells: 99.4;Excitatory neurons: 52.0;Inhibitory neurons: 28.3;Intestinal goblet cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 20.1;HeLa: 23.2;MCF7: 13.5;SCLC-21H: 27.2;SK-BR-3: 24.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075624 Uncertain "Vesicles,Plasma membrane,Centrosome" "Intracellular and membrane" No No "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Vesicles, Plasma membrane" Centrosome "HPA075624: " "unprognostic (1.01e-2)" "prognostic favorable (8.20e-5)" "unprognostic (7.25e-2)" "unprognostic (1.52e-1)" "unprognostic (7.34e-2)" "unprognostic (9.41e-3)" "unprognostic (2.81e-2)" "unprognostic (5.10e-2)" "unprognostic (1.82e-2)" "unprognostic (3.55e-2)" "unprognostic (3.75e-2)" "unprognostic (2.14e-1)" "unprognostic (6.48e-2)" "unprognostic (5.68e-2)" "unprognostic (1.23e-1)" "unprognostic (7.16e-2)" "unprognostic (2.92e-3)" 0.3 1.1 53.5 0.1 55.8 0.2 0.9 57.7 84.9 1.7 43.0 5.7 5.6 0.2 1.8 1.6 0.6 0.8 1.8 60.7 46.2 1.4 45.9 0.3 0.3 48.0 45.4 0.2 42.7 3.4 34.0 0.0 49.1 4.9 5.1 6.8 18.4 0.8 1.1 1.5 6.4 0.1 44.0 0.7 13.7 1.0 47.6 0.3 1.7 2.1 0.8 0.8 0.7 51.9 1.7 20.1 0.1 5.1 0.3 0.1 0.1 0.9 1.6 0.7 1.3 0.6 4.0 0.3 1.4 1.3 0.6 3.2 1.1 0.4 0.1 2.2 2.1 0.8 23.2 1.8 0.8 0.0 0.6 0.8 0.2 0.2 0.3 4.6 0.4 3.2 0.4 0.0 2.3 13.5 0.1 1.0 1.2 6.5 1.8 1.7 1.6 3.5 7.7 1.4 27.2 5.4 0.6 24.9 1.0 0.3 8.2 0.3 0.9 0.0 3.5 0.4 0.4 2.9 0.1 0.3 0.5 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 53.5 55.8 57.7 84.9 60.7 46.2 48.0 45.4 49.1 44.0 47.6 51.9 0.2 0.0 1.1 6.5 1.3 1.3 1.6 1.4 8.0 36.1 1.4 1.4 1.6 1.5 3.4 0.0 4.2 0.0 0.0 2.6 0.0 0.4 0.1 1.0 0.3 0.4 99.4 0.0 52.0 1.0 0.0 0.4 12.8 0.4 0.0 0.5 1.1 8.1 0.2 1.7 28.3 41.9 4.1 0.3 0.0 0.1 0.0 0.1 3.6 8.4 0.0 10.7 0.0 20.1 3.6 0.5 1.8 0.0 3.8 1.5 10.5 0.6 2.3 9.1 0.0 0.3 0.3 0.0 2.4 1.5 0.1 0.1 0.2 0.3 3.2 2.6 RAB37 ENSG00000172794 "RAB37, member RAS oncogene family" Q96AX2 17 74670578-74747335 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.5;brain: 20.8;lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "dendritic cells: 33.4;Excitatory neurons: 33.2;granulocytes: 50.7;Inhibitory neurons: 29.6;NK-cells: 87.6;T-cells: 31.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 269.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 269.7" "Cell line enhanced" "Detected in some" "HEL: 50.6;HMC-1: 58.7;OE19: 25.4;U-266/70: 84.9;U-937: 34.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (2.10e-2)" "unprognostic (7.04e-4)" "unprognostic (5.95e-2)" "unprognostic (9.80e-4)" "unprognostic (3.49e-1)" "unprognostic (7.04e-5)" "unprognostic (1.74e-1)" "unprognostic (1.48e-2)" "unprognostic (7.62e-3)" "unprognostic (9.47e-3)" "unprognostic (3.05e-2)" "unprognostic (2.02e-2)" "prognostic unfavorable (8.80e-6)" "unprognostic (7.30e-2)" "prognostic unfavorable (9.27e-4)" "unprognostic (7.80e-2)" "unprognostic (4.01e-2)" 1.4 1.9 1.5 10.5 2.7 24.5 1.0 20.8 10.5 1.8 0.0 5.4 5.2 1.3 1.8 1.9 1.6 4.8 1.3 1.2 2.8 1.0 12.2 6.8 19.2 11.8 4.6 0.5 0.7 1.7 0.6 1.8 11.3 3.9 5.1 3.3 2.3 0.9 0.6 0.8 8.3 1.9 0.6 17.0 6.7 0.8 11.1 21.3 0.6 2.7 14.9 4.2 1.9 3.7 0.0 7.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 50.6 0.2 0.3 0.1 3.9 58.7 0.5 0.0 0.0 0.0 0.0 0.0 7.3 0.0 18.3 0.0 0.2 15.3 13.0 0.0 25.4 0.0 2.8 0.0 0.0 0.1 0.0 0.8 0.0 0.0 3.6 0.0 2.9 0.2 11.4 0.0 0.0 0.3 0.0 0.0 84.9 3.6 1.1 0.1 34.3 0.0 269.7 13.6 201.5 51.1 28.9 12.9 12.3 22.4 37.8 7.3 12.2 12.5 28.3 63.2 54.0 50.3 1.4 42.8 48.9 1.5 2.7 20.8 10.5 1.2 2.8 11.8 4.6 11.3 0.6 11.1 3.7 0.9 3.2 3.2 1.6 23.1 0.1 0.2 0.3 0.0 7.6 0.8 0.4 1.8 5.7 1.8 0.0 6.2 0.1 33.4 1.3 0.0 1.3 0.0 0.1 0.1 0.9 5.4 16.0 33.2 0.9 0.1 2.0 8.2 0.5 50.7 0.0 2.2 12.6 0.6 3.3 29.6 7.7 14.2 2.2 0.0 0.4 0.6 18.5 0.0 1.9 11.8 1.3 87.6 2.0 1.6 0.4 2.8 1.2 6.3 0.1 0.2 1.5 2.3 1.0 6.6 3.0 1.1 0.0 1.5 0.3 0.1 0.0 31.0 0.5 0.5 0.3 RAB3IP "FLJ22548, RABIN3, RABIN8" ENSG00000127328 "RAB3A interacting protein" Q96QF0 12 69738860-69823204 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 210.4;Early spermatids: 287.3;Late spermatids: 453.9;Oligodendrocyte precursor cells: 261.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 156.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039794 Uncertain Approved "Intermediate filaments" No No "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Intermediate filaments" "HPA039794: AB_10960557" "unprognostic (4.38e-3)" "unprognostic (1.48e-1)" "unprognostic (6.66e-2)" "unprognostic (8.57e-2)" "unprognostic (3.30e-3)" "unprognostic (1.95e-1)" "unprognostic (1.75e-2)" "unprognostic (7.10e-2)" "unprognostic (2.12e-1)" "unprognostic (1.31e-1)" "unprognostic (1.16e-2)" "unprognostic (1.24e-1)" "prognostic favorable (5.68e-13)" "unprognostic (6.17e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "unprognostic (3.37e-1)" 3.7 15.9 17.7 6.4 22.0 25.6 19.9 79.7 16.9 8.4 51.6 21.7 19.2 5.5 44.3 8.6 15.2 15.1 18.3 18.7 18.9 48.5 16.6 14.9 13.6 25.7 21.7 3.1 22.8 26.9 20.2 12.0 26.2 20.8 22.6 88.6 12.8 9.7 9.7 11.8 22.4 4.9 12.1 6.8 18.4 74.7 19.7 12.7 16.2 14.3 15.3 11.8 4.8 25.6 44.1 23.5 14.3 22.9 6.9 3.1 41.0 4.3 9.9 16.9 22.6 67.3 19.1 34.1 13.9 2.3 21.9 33.0 14.7 22.9 29.0 51.7 25.6 25.3 8.4 32.9 6.4 29.9 15.4 7.4 23.3 15.6 52.4 17.5 24.8 44.4 12.1 30.3 9.6 46.8 30.3 12.8 35.7 46.1 25.7 35.3 22.2 35.9 55.1 53.5 56.7 10.2 16.7 28.0 6.4 57.0 47.6 11.1 7.4 7.2 18.3 3.0 20.3 14.2 63.4 156.9 17.5 18.3 11.2 1.8 5.2 7.2 4.2 1.9 8.5 9.2 7.5 6.8 5.6 8.6 9.3 9.1 6.9 7.8 2.3 5.1 12.6 4.4 17.7 22.0 79.7 16.9 18.7 18.9 25.7 21.7 26.2 12.1 19.7 25.6 4.0 60.9 51.1 19.6 17.7 23.6 55.6 28.8 19.4 210.4 44.6 13.0 50.2 85.8 48.8 51.5 110.5 21.7 6.4 33.1 37.2 64.6 287.3 79.7 5.2 8.7 40.8 14.1 22.6 31.8 8.2 6.4 39.3 119.7 2.5 19.3 7.1 16.5 3.5 28.6 186.1 39.3 46.8 1.9 7.5 453.9 4.4 8.0 5.4 9.4 16.6 96.6 4.1 261.9 104.1 51.1 38.6 3.8 25.9 77.9 46.1 82.1 54.4 95.8 6.6 31.8 12.3 48.9 37.7 24.2 29.8 8.5 15.1 3.5 45.8 76.7 RAB9A RAB9 ENSG00000123595 "RAB9A, member RAS oncogene family" P51151 X 13689128-13710504 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 345.3;Syncytiotrophoblasts: 370.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003094, CAB016411" Supported Uncertain Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "CAB016411: AB_630176, HPA003094: AB_1079736" "unprognostic (3.40e-2)" "unprognostic (1.36e-2)" "unprognostic (3.56e-3)" "unprognostic (3.08e-2)" "unprognostic (1.62e-1)" "unprognostic (2.56e-2)" "unprognostic (1.79e-2)" "unprognostic (1.45e-1)" "unprognostic (8.77e-2)" "unprognostic (8.23e-2)" "unprognostic (1.27e-2)" "unprognostic (4.88e-2)" "prognostic favorable (3.35e-5)" "unprognostic (3.93e-2)" "unprognostic (3.19e-1)" "unprognostic (1.46e-1)" "unprognostic (2.68e-2)" 28.9 51.7 24.2 18.4 27.2 56.0 32.8 28.3 28.2 31.4 21.8 28.4 14.9 29.4 21.3 29.7 21.5 22.8 20.7 23.4 26.0 30.3 24.9 24.9 25.1 28.0 25.3 28.2 33.2 38.1 15.5 28.7 28.7 20.2 25.0 21.7 37.0 18.9 19.7 37.0 19.1 22.1 28.5 22.0 21.4 7.6 25.0 16.5 21.1 16.5 31.7 27.4 27.9 32.1 34.8 18.1 22.9 54.5 75.1 59.7 20.4 19.0 66.4 28.5 41.2 19.6 37.7 31.3 45.7 29.9 68.1 34.8 34.4 40.4 27.8 69.6 53.4 9.9 36.6 22.9 45.0 17.7 25.8 64.6 69.5 35.8 38.2 45.7 26.8 17.3 19.5 44.8 30.9 23.9 16.8 28.8 24.7 24.0 34.1 22.7 24.2 94.7 78.8 31.7 18.8 13.2 40.3 56.3 69.3 56.8 31.4 18.5 21.1 21.5 11.2 76.9 11.6 35.4 66.4 12.8 21.5 15.1 21.5 34.1 37.7 17.5 38.1 25.3 29.9 20.0 20.7 31.9 26.5 14.2 15.3 26.3 22.5 31.0 24.1 29.1 18.0 22.0 24.2 27.2 28.3 28.2 23.4 26.0 28.0 25.3 28.7 28.5 25.0 32.1 25.4 48.1 27.3 19.9 35.0 64.7 69.0 73.4 29.6 8.7 35.9 39.0 16.6 42.9 64.1 33.1 0.0 83.6 121.0 85.3 80.3 135.0 0.6 78.8 46.2 23.7 24.5 27.8 11.1 64.0 60.5 39.2 23.4 105.8 45.1 13.5 14.3 19.2 54.9 15.2 13.7 32.2 52.9 45.0 104.9 2.2 37.6 46.7 56.9 6.5 345.3 50.9 68.0 33.7 36.6 81.1 103.1 40.3 53.8 93.1 30.7 68.9 42.8 9.4 13.1 28.1 37.2 9.7 17.7 44.5 83.4 370.4 75.6 51.4 26.6 111.8 RAB9B RAB9L ENSG00000123570 "RAB9B, member RAS oncogene family" Q9NP90 X 103822327-103832257 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 21.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 21.3;Cardiomyocytes: 79.0;Excitatory neurons: 28.4;Inhibitory neurons: 18.7;Muller glia cells: 32.2;Oligodendrocyte precursor cells: 37.7;Peritubular cells: 30.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 4.5;MOLT-4: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061932 Approved "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA061932: AB_2684640" "unprognostic (1.69e-2)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (7.28e-5)" "unprognostic (5.81e-2)" "unprognostic (3.89e-2)" "unprognostic (8.40e-2)" "unprognostic (1.42e-2)" "unprognostic (8.34e-2)" "unprognostic (8.29e-2)" "unprognostic (3.52e-4)" "unprognostic (1.10e-1)" "unprognostic (9.21e-4)" "unprognostic (1.37e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" 1.8 2.8 6.4 0.9 6.6 0.1 1.3 8.1 7.2 3.0 0.0 6.5 1.0 5.0 2.4 8.3 6.8 2.4 21.5 6.2 8.8 0.4 0.1 0.7 0.6 4.0 3.6 7.2 1.0 3.9 5.1 0.2 6.8 7.1 2.2 5.2 1.1 9.5 9.4 0.5 1.7 9.8 3.7 0.5 2.2 1.8 8.8 1.5 1.4 5.6 0.4 7.0 1.6 4.7 0.0 0.0 2.9 1.5 0.8 0.1 0.1 0.7 1.8 1.8 1.7 0.2 0.0 0.1 1.7 1.5 1.1 0.0 0.5 0.1 1.6 0.1 1.9 0.1 0.0 0.0 0.2 0.2 0.1 0.4 0.0 0.8 0.0 1.8 0.1 4.5 0.0 1.1 0.1 1.3 3.7 0.0 0.5 0.0 0.5 3.2 3.3 0.1 1.0 0.3 3.0 2.1 0.2 0.1 0.6 0.5 0.3 0.2 0.1 0.1 0.5 1.0 0.6 0.1 0.0 0.2 1.6 0.2 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.8 0.0 0.1 0.1 0.0 6.4 6.6 8.1 7.2 6.2 8.8 4.0 3.6 6.8 3.7 8.8 4.7 1.0 0.0 2.4 8.5 0.7 0.4 0.7 0.1 0.6 21.3 1.6 1.9 79.0 0.0 0.7 0.0 0.0 0.4 0.2 0.5 0.0 0.5 0.0 0.3 0.7 2.4 7.7 1.3 28.4 1.0 0.3 4.1 0.0 0.2 4.5 2.8 0.7 0.0 0.3 0.0 18.7 0.7 0.0 0.0 0.4 0.9 6.5 0.2 0.0 1.9 0.0 32.2 2.1 37.7 6.2 1.0 2.5 30.1 0.1 0.2 0.1 0.2 0.8 3.6 6.6 2.3 5.0 0.8 0.9 0.5 0.3 0.0 0.2 4.7 0.6 0.2 RAD21L1 "dJ545L17.2, RAD21L" ENSG00000244588 "RAD21 cohesin complex component like 1" Q9H4I0 20 1226056-1296421 "Predicted intracellular proteins" "Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "testis: 11.5" "Group enriched" "Detected in some" 14 "Early spermatids: 110.9;Late spermatids: 109.4;Spermatocytes: 29.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.5;TIME: 1.5" "Low region specificity" "Detected in some" HPA053282 Approved NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "HPA053282: AB_2682099" "unprognostic (2.90e-1)" "unprognostic (3.35e-1)" "unprognostic (1.62e-4)" "unprognostic (2.04e-1)" "unprognostic (8.87e-4)" "unprognostic (1.15e-1)" "unprognostic (1.25e-1)" "unprognostic (1.84e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 1.5 0.8 0.3 0.0 0.0 0.0 0.1 0.2 0.6 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 110.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 109.4 0.6 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.4 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RAD23B "HHR23B, HR23B, P58" ENSG00000119318 "RAD23 homolog B, nucleotide excision repair protein" P54727 9 107283137-107332192 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 420.5;Late spermatids: 1201.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029718, HPA029720, CAB033868" Enhanced Supported Nucleoplasm,Cytosol No No 5900000 "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "CAB033868: AB_1128418, HPA029718: AB_10600116, HPA029720: AB_10601008" "unprognostic (3.95e-3)" "unprognostic (1.01e-2)" "unprognostic (2.28e-2)" "unprognostic (8.14e-2)" "unprognostic (4.71e-2)" "prognostic unfavorable (2.58e-4)" "unprognostic (2.94e-1)" "prognostic unfavorable (6.71e-4)" "unprognostic (1.34e-1)" "unprognostic (3.72e-1)" "unprognostic (3.31e-2)" "unprognostic (1.20e-1)" "unprognostic (2.94e-3)" "unprognostic (2.69e-2)" "unprognostic (2.43e-1)" "unprognostic (7.49e-3)" "unprognostic (1.04e-1)" 73.8 47.8 26.6 44.4 27.0 82.8 48.5 40.4 37.4 42.8 22.0 47.7 41.9 41.9 68.8 63.6 40.9 34.1 48.7 29.0 29.2 44.4 140.8 39.3 39.4 26.9 27.0 37.8 64.5 50.4 30.5 77.7 26.3 48.2 47.7 42.1 38.4 43.5 153.0 64.7 40.6 55.0 22.5 36.2 41.5 59.4 27.7 58.4 42.6 123.5 49.9 67.5 42.8 30.7 132.9 114.9 158.6 102.9 107.5 166.6 179.9 200.6 162.3 172.8 116.9 190.1 140.5 184.8 79.3 218.6 156.4 181.2 221.0 175.9 172.9 126.4 73.0 96.2 112.0 147.6 140.3 174.2 79.3 141.1 161.3 165.3 248.0 136.0 124.3 79.6 158.3 133.6 159.5 215.0 169.6 88.3 170.5 231.2 133.0 125.3 209.6 87.8 149.8 122.1 144.9 98.2 138.8 193.1 125.8 237.5 197.7 70.5 114.3 129.0 127.0 161.6 152.5 91.9 181.2 98.5 138.0 101.7 138.0 0.9 1.1 1.1 1.9 1.2 2.1 1.8 1.1 1.6 1.0 2.1 1.7 1.5 2.9 2.3 0.8 1.1 2.2 0.6 26.6 27.0 40.4 37.4 29.0 29.2 26.9 27.0 26.3 22.5 27.7 30.7 49.7 44.8 40.4 32.3 54.7 195.5 148.1 40.5 79.1 40.5 65.3 36.6 117.4 68.6 42.2 35.0 27.1 269.7 37.1 82.9 50.9 89.2 420.5 69.8 80.8 68.7 101.0 76.1 54.9 77.4 259.7 79.3 60.6 90.8 36.2 83.0 55.6 209.9 99.5 50.5 47.2 83.8 38.7 65.6 131.1 1201.4 75.5 70.7 74.7 38.4 83.7 40.4 39.1 50.3 54.1 81.0 50.5 87.3 89.3 146.0 51.2 95.9 47.6 43.9 78.9 71.6 88.5 45.3 74.7 126.9 240.9 291.8 50.5 91.1 74.9 141.2 RAD54L "hHR54, hRAD54, RAD54A" ENSG00000085999 "RAD54 like" Q92698 1 46246461-46278480 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.4;testis: 15.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 7.2;Extravillous trophoblasts: 9.4;Glandular and luminal cells: 8.0;Spermatocytes: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.1" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028954, HPA051537" Approved Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA028954: AB_2672840, HPA051537: AB_2681525" "unprognostic (2.12e-2)" "prognostic favorable (6.67e-4)" "unprognostic (5.12e-2)" "unprognostic (5.36e-3)" "unprognostic (3.24e-1)" "unprognostic (1.08e-2)" "unprognostic (9.75e-6)" "unprognostic (3.91e-2)" "unprognostic (2.17e-3)" "unprognostic (2.95e-2)" "unprognostic (1.77e-4)" "unprognostic (5.58e-2)" "unprognostic (1.11e-16)" "unprognostic (6.76e-3)" "unprognostic (1.66e-1)" "unprognostic (2.67e-1)" "unprognostic (1.74e-1)" 0.5 0.7 3.0 4.1 3.8 8.7 1.0 4.3 3.9 1.3 2.1 3.2 2.0 0.7 0.1 5.4 0.4 0.5 0.7 2.9 2.5 1.4 0.5 1.2 5.5 3.2 3.0 0.5 0.5 0.3 0.4 3.4 3.8 1.0 4.6 0.4 0.9 0.4 1.2 2.3 2.8 1.7 2.8 2.8 1.5 15.6 3.1 15.4 1.8 0.0 8.3 0.8 1.8 3.7 22.2 16.1 46.8 29.1 3.3 2.4 43.9 25.8 11.3 42.8 43.3 33.3 14.2 42.5 19.1 11.0 38.5 22.2 44.6 14.5 36.8 23.7 43.0 53.0 49.7 32.1 0.1 54.0 29.3 1.6 1.2 42.1 12.5 6.9 13.5 49.7 38.2 41.7 23.1 20.4 68.9 60.0 42.5 19.4 25.2 52.8 26.8 19.0 9.4 17.5 22.4 16.3 18.4 25.2 5.7 38.0 9.1 37.7 5.7 43.9 26.1 23.6 43.7 17.6 10.6 46.9 11.5 35.1 18.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.2 3.0 3.8 4.3 3.9 2.9 2.5 3.2 3.0 3.8 2.8 3.1 3.7 0.0 0.0 0.0 1.0 0.7 0.3 0.7 0.5 1.8 0.0 0.5 0.5 0.8 0.0 0.1 0.0 0.0 4.3 0.4 1.8 0.0 0.3 2.7 2.3 0.8 0.5 0.0 7.2 2.8 0.0 9.4 1.1 0.5 8.0 4.5 5.6 0.4 0.0 2.6 0.0 1.1 1.3 0.0 0.3 0.3 0.7 0.0 0.4 0.0 0.0 0.0 0.0 1.0 1.0 2.9 0.3 0.1 0.0 4.7 0.4 0.4 0.0 0.1 0.0 0.0 0.4 4.0 12.4 5.6 3.1 0.3 1.6 1.1 0.2 2.9 1.0 RAET1E "bA350J20.7, LETAL, ULBP4" ENSG00000164520 "Retinoic acid early transcript 1E" Q8TD07 6 149883375-149898102 "Predicted intracellular proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 21.9;esophagus: 62.8;skin 1: 21.6;vagina: 27.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 12.4;Early spermatids: 10.0;Late spermatids: 5.6;Respiratory ciliated cells: 14.6;Squamous epithelial cells: 17.2;Suprabasal keratinocytes: 6.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 19.6;HeLa: 24.4;hTCEpi: 19.1;SiHa: 9.9;U-87 MG: 7.7" HPA054022 Supported "Focal adhesion sites,Cytosol" "Intracellular and membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Focal adhesion sites" Cytosol "HPA054022: AB_2797250" "unprognostic (1.67e-2)" "unprognostic (2.10e-1)" "unprognostic (3.49e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (1.36e-3)" "unprognostic (4.80e-4)" "unprognostic (1.11e-1)" "unprognostic (3.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (7.47e-5)" "unprognostic (2.41e-2)" "unprognostic (3.18e-2)" "unprognostic (3.17e-2)" "unprognostic (1.06e-1)" 3.7 0.8 0.6 0.1 0.4 0.1 1.9 1.0 0.7 21.9 0.8 0.2 0.1 0.3 0.0 62.8 0.8 0.1 0.5 0.5 0.5 2.2 0.1 0.3 0.1 0.4 0.3 0.1 0.1 0.0 0.2 0.5 0.5 0.3 0.3 0.1 12.9 0.3 1.6 21.6 0.1 0.5 0.1 0.9 0.3 0.4 0.4 0.1 0.3 0.2 11.6 1.9 27.5 0.5 1.8 1.0 0.0 0.0 0.2 1.3 0.0 0.1 0.9 0.1 0.3 0.0 4.3 0.0 2.6 4.4 1.4 1.7 0.0 19.6 0.2 0.3 0.0 0.1 24.4 0.0 0.0 0.0 0.0 0.4 19.1 1.0 3.9 0.4 0.1 0.1 0.0 1.3 0.8 0.0 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.3 0.4 0.9 0.2 0.0 9.9 1.5 0.0 0.0 1.2 0.0 1.8 0.8 0.3 0.2 0.9 0.0 0.0 0.0 7.7 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 1.0 0.7 0.5 0.5 0.4 0.3 0.5 0.1 0.4 0.5 1.0 0.0 0.0 0.3 0.0 2.2 1.1 12.4 1.8 0.6 0.3 0.6 0.3 1.5 3.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 2.5 0.1 1.0 0.0 0.0 0.9 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 1.1 0.1 0.0 0.0 0.3 5.6 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.5 1.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 14.6 0.4 0.0 0.3 0.4 0.0 0.2 17.2 6.5 0.0 0.2 0.1 0.2 1.6 RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.4;esophagus: 15.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 42.9;Club cells: 14.8;Ionocytes: 12.2;Respiratory ciliated cells: 23.3;Squamous epithelial cells: 8.9;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.5;head and neck cancer: 4.7;lung cancer: 1.2;thyroid cancer: 1.5;urothelial cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 29.5;hTCEpi: 22.6;SiHa: 11.9;U-87 MG: 9.3" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (4.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-3)" "unprognostic (1.49e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (5.35e-4)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" "unprognostic (8.85e-2)" "unprognostic (9.11e-2)" 2.8 8.4 0.4 0.4 0.3 0.0 0.6 0.0 0.4 4.1 0.0 0.2 0.1 0.3 0.7 15.1 0.6 0.7 0.6 0.4 0.3 0.9 0.1 0.5 0.1 0.3 0.6 0.7 0.1 0.2 0.3 0.1 0.1 0.7 0.1 0.1 3.7 1.0 0.2 2.7 0.2 0.6 0.0 0.1 0.4 0.3 0.7 0.0 0.4 0.1 1.1 1.8 6.0 0.0 1.0 1.4 0.0 1.7 2.3 1.7 0.0 0.8 3.0 1.3 1.9 0.0 1.5 0.0 0.6 1.7 1.4 2.7 0.9 5.3 1.1 0.3 1.6 0.5 29.5 0.0 0.7 0.0 0.0 3.3 22.6 3.5 1.7 1.5 0.3 0.7 0.3 0.2 0.6 1.3 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 1.0 3.2 0.3 0.3 11.9 0.5 0.0 0.1 0.4 0.4 1.6 0.6 0.5 1.6 0.8 0.0 0.0 0.0 9.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.4 0.4 0.3 0.3 0.6 0.1 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 3.1 5.1 42.9 2.8 0.0 0.4 0.4 0.1 1.5 14.8 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.4 0.1 1.3 0.0 0.0 0.0 1.3 0.0 1.9 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.7 0.1 0.9 0.0 3.6 0.0 0.0 0.8 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.0 0.0 23.3 0.0 0.0 0.2 1.1 0.0 0.3 8.9 1.7 0.1 0.3 0.5 0.0 8.1 RAMP2 ENSG00000131477 "Receptor activity modifying protein 2" O60895 17 42758447-42763041 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 1066.8;Endothelial cells: 562.9;Hepatic stellate cells: 344.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 21 "dendritic cells: 2.9" "Cell line enhanced" "Detected in many" "ASC diff: 120.4;EFO-21: 80.5;HUVEC TERT2: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052020 Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA052020: AB_2681697" "unprognostic (8.64e-2)" "unprognostic (2.12e-2)" "unprognostic (8.03e-2)" "unprognostic (1.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (6.79e-2)" "unprognostic (1.28e-2)" "unprognostic (6.96e-3)" "unprognostic (4.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.25e-1)" 190.0 29.0 60.4 19.2 61.8 0.1 168.9 61.7 72.3 100.7 67.7 35.7 12.5 63.1 27.8 25.1 51.7 39.6 123.2 59.3 65.8 70.5 16.7 163.3 26.2 65.7 68.1 33.0 17.1 23.8 20.8 97.0 72.7 42.1 21.1 4.1 45.9 27.5 43.3 55.9 44.1 72.6 62.7 40.2 33.9 11.9 66.6 11.4 71.7 98.7 24.5 45.9 49.6 62.4 0.1 1.1 4.9 0.1 120.4 6.2 4.0 0.9 2.1 10.2 4.9 11.5 0.1 0.0 80.5 3.0 0.5 0.0 4.6 0.1 8.9 0.0 0.2 0.0 0.7 3.7 3.0 0.0 0.0 4.2 0.1 1.8 0.4 3.5 37.6 1.5 0.1 0.2 0.6 0.0 0.6 0.8 23.3 0.0 0.0 0.1 0.1 0.0 0.6 0.6 4.8 9.8 2.9 0.0 17.3 4.8 1.2 3.2 6.7 19.3 7.1 0.4 2.4 0.0 0.1 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 60.4 61.8 61.7 72.3 59.3 65.8 65.7 68.1 72.7 62.7 66.6 62.4 1066.8 0.0 5.7 1.6 6.2 34.4 5.4 0.9 9.6 0.6 24.0 24.8 2.2 0.0 1.0 3.7 0.0 1.1 3.7 0.1 3.9 0.6 1.6 22.2 52.8 562.9 4.2 0.0 0.2 0.7 1.7 126.9 3.1 38.5 0.0 1.4 344.8 1.3 3.4 0.0 1.0 0.2 20.3 8.4 40.5 3.6 38.8 4.1 23.2 45.0 2.6 15.5 0.0 1.5 0.3 0.0 0.0 21.8 5.2 4.8 0.0 1.0 0.1 1.8 6.6 10.5 26.3 26.6 59.1 2.6 27.6 1.5 4.0 14.0 0.1 4.3 RAPGEF5 "GFR, KIAA0277, MR-GEF" ENSG00000136237 "Rap guanine nucleotide exchange factor 5" Q92565 7 22118236-22357154 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 152.1;parathyroid gland: 387.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 504.6;Inhibitory neurons: 193.4;Microglial cells: 138.7;Oligodendrocytes: 640.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 21.1;HUVEC TERT2: 45.0;SCLC-21H: 34.1;TIME: 25.8;U-698: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057821, HPA076772" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA057821: AB_2683538, HPA076772: AB_2686814" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (5.22e-2)" "prognostic favorable (3.52e-5)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (1.31e-1)" "unprognostic (3.76e-2)" "unprognostic (6.36e-3)" "unprognostic (6.57e-2)" "unprognostic (2.55e-1)" "unprognostic (8.26e-3)" 21.0 12.7 30.7 7.0 82.9 0.9 16.4 76.1 58.5 8.9 2.9 9.5 7.5 8.8 4.8 13.9 8.3 16.8 16.8 45.7 46.9 16.7 21.8 37.5 14.3 115.3 71.8 6.5 20.1 387.8 7.4 67.2 107.1 5.1 11.0 4.2 7.6 5.7 5.1 9.2 8.3 12.1 82.0 50.9 7.0 6.4 59.8 15.7 11.7 11.1 10.7 9.3 11.9 152.1 2.8 0.0 4.6 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 5.5 1.4 21.1 1.1 0.3 0.7 13.0 2.8 1.9 0.0 0.0 4.2 0.3 0.0 5.4 0.1 0.0 0.1 0.5 2.4 1.3 0.7 0.7 45.0 5.9 4.8 0.1 0.0 1.2 3.0 0.1 3.6 5.4 4.0 5.2 0.0 7.4 4.2 1.9 34.1 9.0 0.5 6.0 0.1 0.7 3.0 0.1 25.8 0.0 1.0 0.4 1.1 10.9 2.5 37.4 0.5 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 82.9 76.1 58.5 45.7 46.9 115.3 71.8 107.1 82.0 59.8 152.1 125.5 9.6 16.5 13.4 3.1 11.0 4.2 2.4 86.0 30.6 8.8 5.5 10.0 15.7 3.8 0.0 0.0 0.3 0.6 16.0 1.9 6.5 61.5 3.3 1.2 70.1 7.2 0.4 504.6 7.0 0.1 5.3 16.3 10.8 8.2 0.1 86.0 6.3 0.2 23.5 193.4 18.3 2.0 3.1 2.0 65.2 1.8 0.9 7.2 138.7 0.0 0.6 0.0 28.1 640.8 5.0 20.3 4.9 12.9 3.0 18.1 0.3 0.5 1.6 85.5 1.4 21.5 1.2 1.6 19.8 11.2 0.3 2.4 1.9 10.1 4.4 RARA "NR1B1, RAR" ENSG00000131759 "Retinoic acid receptor alpha" P10276 17 40309180-40357643 "Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 52.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 221.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058282, HPA071548" Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli, Actin filaments, Cytosol" "HPA058282: AB_2683666, HPA071548: " "unprognostic (8.05e-3)" "unprognostic (1.89e-1)" "unprognostic (9.48e-3)" "prognostic favorable (2.60e-4)" "unprognostic (8.67e-3)" "unprognostic (4.87e-3)" "unprognostic (2.77e-1)" "unprognostic (5.73e-2)" "unprognostic (1.45e-1)" "unprognostic (3.54e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (2.29e-3)" "unprognostic (1.59e-2)" "unprognostic (5.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" 47.6 21.1 3.2 28.3 4.4 59.6 37.2 7.2 16.5 43.7 5.1 31.0 28.4 32.2 10.7 14.9 40.7 41.3 40.8 7.0 5.7 24.1 42.3 58.4 16.4 5.3 2.7 40.8 14.7 11.3 30.6 25.7 2.8 29.8 13.2 18.3 20.6 21.3 62.6 24.8 32.2 28.6 1.8 41.7 22.9 28.8 4.9 10.0 26.9 17.4 11.8 30.3 30.2 4.3 18.0 41.9 11.8 20.5 23.4 35.9 12.5 14.9 21.8 21.5 13.6 28.6 15.1 9.6 22.7 33.2 18.9 51.1 14.2 33.9 12.0 77.5 21.4 26.6 21.2 29.8 37.0 9.4 81.3 48.2 10.0 22.7 29.2 75.8 30.9 8.4 17.6 20.2 23.7 221.5 6.4 34.2 10.7 16.2 13.3 12.9 71.3 37.0 12.2 14.4 5.4 40.5 31.0 124.8 42.1 11.7 119.1 36.6 35.8 25.3 45.3 44.2 15.4 48.7 16.9 8.3 38.4 18.7 77.1 26.3 8.9 34.6 3.2 14.6 5.1 2.0 3.6 3.8 12.4 1.7 1.5 2.8 52.6 5.9 19.5 3.8 3.1 5.0 3.2 4.4 7.2 16.5 7.0 5.7 5.3 2.7 2.8 1.8 4.9 4.3 35.6 3.2 7.0 2.3 43.4 19.5 25.6 8.4 18.8 23.2 35.4 17.5 3.8 10.0 5.5 7.3 6.2 2.2 36.9 41.2 13.7 16.7 60.5 20.7 22.0 28.4 9.6 5.7 5.4 19.2 5.8 28.5 10.7 18.4 35.5 13.9 26.0 28.8 12.3 3.3 2.6 13.1 6.1 45.4 65.5 66.2 41.7 56.9 28.4 2.8 26.1 11.8 6.2 4.0 0.3 22.0 33.1 23.0 21.0 13.4 70.9 17.7 4.9 10.2 32.9 42.1 26.7 3.6 7.6 7.1 18.9 5.2 31.7 6.5 16.5 19.3 RARG "NR1B3, RARC" ENSG00000172819 "Retinoic acid receptor gamma" P13631 12 53210567-53232980 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 141.6;skin 1: 121.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 42.7;Squamous epithelial cells: 69.9;Suprabasal keratinocytes: 55.8;Urothelial cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.8" "Group enriched" "Detected in all" 4 "dendritic cells: 6.7;T-cells: 18.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 101.0;MCF7: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053883 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA053883: AB_2682292" "unprognostic (7.29e-2)" "unprognostic (1.95e-2)" "unprognostic (6.11e-2)" "prognostic unfavorable (3.68e-6)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" "unprognostic (2.28e-1)" "unprognostic (1.08e-2)" "unprognostic (3.54e-3)" "unprognostic (7.21e-3)" "unprognostic (3.78e-3)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (5.41e-3)" "unprognostic (1.98e-2)" "unprognostic (5.94e-3)" "unprognostic (7.41e-2)" 17.4 16.2 10.2 5.7 9.7 3.7 19.4 13.0 10.9 55.0 10.8 22.7 2.5 23.3 6.0 141.6 27.2 15.7 17.3 9.7 9.5 12.5 3.2 15.2 5.9 10.3 10.0 20.5 8.5 7.2 8.7 9.5 9.3 26.9 7.8 3.9 30.6 16.2 6.9 121.4 10.4 13.0 10.0 10.2 14.5 4.8 9.5 5.1 22.6 10.6 22.5 26.2 69.3 10.0 22.8 24.7 5.5 50.9 55.0 46.8 1.7 23.2 50.0 29.7 23.3 8.3 101.0 0.5 12.5 93.6 16.2 74.3 18.4 44.6 7.4 5.7 9.4 3.3 18.6 7.4 23.2 0.0 9.1 34.8 63.9 28.5 6.4 74.7 12.7 4.6 0.8 9.8 11.9 110.3 1.3 1.1 16.3 30.4 42.7 7.3 1.9 18.1 8.9 37.1 4.4 22.9 47.0 50.6 32.1 6.8 43.9 1.4 13.8 35.4 16.5 23.6 1.5 4.2 2.6 1.8 43.4 3.8 51.3 1.8 3.1 0.9 7.4 0.9 18.8 2.0 6.5 5.4 6.7 0.6 5.2 4.7 0.0 2.3 0.0 0.6 1.8 4.0 10.2 9.7 13.0 10.9 9.7 9.5 10.3 10.0 9.3 10.0 9.5 10.0 10.7 3.2 7.0 21.2 2.5 34.2 24.1 21.6 42.7 0.5 18.0 15.6 3.7 11.5 11.1 3.7 2.1 7.5 6.2 3.2 0.0 10.5 0.1 3.6 14.4 11.0 1.8 0.8 2.5 5.1 1.2 19.6 13.7 3.4 1.3 0.3 20.3 0.1 2.7 0.0 3.0 2.1 12.2 4.1 13.3 0.5 5.3 4.9 8.8 6.5 1.8 3.6 5.2 7.1 0.7 14.3 4.4 5.3 3.0 19.2 0.2 0.5 3.9 5.2 6.6 9.5 22.0 0.8 5.6 69.9 55.8 1.8 7.2 0.4 5.5 45.7 RARRES1 "LXNL, TIG1" ENSG00000118849 "Retinoic acid receptor responder 1" P49788 3 158696892-158732489 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 221.9;fallopian tube: 206.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 217.1;Club cells: 621.4;Prostatic glandular cells: 312.9;Urothelial cells: 737.7" "Cancer enhanced" "Detected in all" "urothelial cancer: 93.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 10 "CAPAN-2: 1319.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003892 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "Endoplasmic reticulum" "HPA003892: AB_1856079" "unprognostic (5.76e-3)" "unprognostic (2.13e-1)" "unprognostic (8.85e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (9.29e-4)" "unprognostic (7.09e-2)" "unprognostic (8.93e-2)" "unprognostic (3.86e-1)" "unprognostic (7.16e-3)" "unprognostic (1.47e-2)" "unprognostic (6.42e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.88e-6)" "unprognostic (3.49e-1)" "unprognostic (1.33e-1)" "unprognostic (7.73e-2)" "unprognostic (1.15e-1)" 221.9 21.3 1.0 65.1 1.5 0.6 44.6 1.5 1.7 74.6 11.3 31.7 5.1 25.9 27.0 11.3 206.4 19.7 81.5 1.5 0.8 25.1 4.2 52.7 18.9 0.6 0.4 60.5 10.0 0.2 27.7 3.5 0.4 78.6 36.2 0.9 165.3 37.2 5.6 8.3 38.5 51.2 0.4 2.7 23.7 4.5 1.0 1.8 20.4 2.8 6.2 92.1 32.2 1.4 19.2 6.9 0.2 1.0 4.0 12.6 0.3 1.8 5.7 1.0 1.4 1.4 1319.3 0.0 1.2 0.9 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.0 0.1 12.0 0.0 0.0 131.3 0.0 0.5 0.0 8.9 2.8 0.0 0.0 0.0 0.4 0.0 0.0 0.2 1.7 5.8 0.0 0.0 0.0 0.1 0.3 22.9 0.5 1.7 16.7 1.3 0.3 0.0 1.9 2.3 1.3 1.1 0.0 4.6 0.0 0.0 0.0 0.0 1.5 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.0 1.5 1.5 1.7 1.5 0.8 0.6 0.4 0.4 0.4 1.0 1.4 5.2 0.0 0.6 2.3 0.9 0.5 217.1 92.7 11.4 0.4 99.7 35.6 0.9 11.5 621.4 14.7 0.0 2.9 1.6 59.0 0.0 10.5 29.5 14.4 98.4 18.1 37.5 3.6 14.2 4.7 0.8 101.3 1.1 16.9 29.9 0.3 31.8 6.0 10.8 0.0 10.6 102.3 40.7 1.6 1.7 33.1 10.8 11.0 5.4 1.9 0.0 4.2 0.0 4.5 7.6 2.3 106.1 1.2 1.2 312.9 140.7 19.7 149.3 0.7 0.0 7.7 46.7 3.8 0.7 7.8 0.4 11.4 3.3 0.1 88.3 737.7 RARRES2 "HP10433, TIG2" ENSG00000106538 "Retinoic acid receptor responder 2" Q99969 7 150338317-150341662 "Plasma proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 2400.4;liver: 1994.6;pancreas: 1482.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 659.2;Hepatocytes: 2819.0;Muller glia cells: 785.1" "Cancer enhanced" "Detected in all" "liver cancer: 420.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 5.4" "Group enriched" "Detected in many" 6 "AF22: 132.9;Hep G2: 213.8;HHSteC: 172.9;NTERA-2: 411.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 75000000 460000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (2.31e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (2.72e-2)" "unprognostic (2.82e-3)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (5.29e-2)" "unprognostic (2.50e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.83e-4)" "unprognostic (2.94e-2)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (5.17e-2)" 525.6 2400.4 61.0 87.4 62.1 0.4 295.6 56.2 70.2 522.4 321.7 386.8 53.2 359.2 55.9 78.7 408.5 116.5 212.7 62.0 63.3 271.9 1994.6 466.8 109.8 65.9 73.6 626.3 1482.0 627.1 104.1 59.0 63.3 262.5 78.3 33.9 56.2 114.7 18.3 60.4 185.9 103.0 64.8 149.5 180.0 26.9 64.5 9.8 85.0 34.6 63.1 265.3 380.7 66.7 0.0 0.1 132.9 0.3 0.0 0.0 2.1 11.9 25.2 4.2 17.2 1.2 8.2 1.1 15.0 2.9 1.3 0.5 0.0 0.0 0.0 2.4 0.5 0.6 23.6 213.8 172.9 2.2 0.4 36.4 0.0 0.0 0.0 2.8 0.0 0.4 0.4 0.4 4.2 0.9 2.1 2.4 411.9 1.2 0.0 0.1 17.1 0.4 2.8 1.1 0.6 1.2 2.3 0.1 0.4 1.9 0.6 0.0 0.0 0.4 1.8 0.8 0.6 1.4 0.9 1.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 5.4 0.0 0.0 61.0 62.1 56.2 70.2 62.0 63.3 65.9 73.6 63.3 64.8 64.5 66.7 47.1 67.3 32.0 9.4 7.0 35.1 80.7 16.8 15.9 7.0 26.2 39.0 75.0 381.8 45.0 82.8 2.1 10.1 1.9 172.6 103.7 19.8 3.7 39.9 128.7 27.1 97.4 32.0 0.4 659.2 4.3 469.6 8.2 16.4 12.0 207.5 84.6 2819.0 11.6 10.1 0.4 233.9 541.2 53.8 42.4 19.3 454.2 8.9 44.4 7.5 1.0 785.1 0.0 9.0 0.3 209.1 107.4 194.9 1.2 82.0 1.2 269.1 29.8 25.4 13.1 302.5 181.1 4.9 5.2 4.4 28.8 14.6 12.3 307.5 418.7 31.9 RASA2 GAP1M ENSG00000155903 "RAS p21 protein activator 2" Q15283 3 141487027-141615344 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 196.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035374, HPA035375" Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Vesicles "HPA035374: AB_10602122, HPA035375: AB_2674596" "unprognostic (1.85e-1)" "unprognostic (8.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.38e-2)" "unprognostic (1.18e-1)" "unprognostic (3.36e-3)" "unprognostic (9.62e-3)" "unprognostic (2.57e-1)" "unprognostic (1.38e-1)" "unprognostic (9.21e-2)" "unprognostic (4.23e-2)" "unprognostic (8.93e-2)" "prognostic unfavorable (7.62e-7)" "unprognostic (1.17e-1)" "unprognostic (2.56e-1)" "unprognostic (1.61e-1)" "prognostic favorable (4.34e-5)" 7.3 4.7 5.1 15.4 6.0 21.9 10.0 7.1 6.4 9.8 3.2 6.6 5.3 8.4 7.3 7.3 7.8 6.7 4.6 5.3 4.9 5.8 5.1 9.7 21.3 4.0 3.6 9.7 5.2 4.4 6.2 8.3 3.5 6.5 7.2 14.6 8.1 5.0 3.8 11.2 8.5 6.0 3.1 12.4 5.4 4.7 4.7 13.3 6.0 3.3 17.2 8.8 8.8 5.6 24.6 4.5 9.5 7.2 10.2 12.6 13.5 17.4 34.0 11.0 13.5 10.5 7.9 15.6 11.7 15.2 10.6 10.0 6.8 7.5 20.0 8.5 6.7 8.4 3.8 3.8 5.4 16.1 21.0 7.3 6.6 10.0 11.8 13.3 14.1 13.1 7.7 19.7 11.0 3.6 21.2 13.0 11.1 8.1 3.2 7.9 16.0 19.5 10.9 8.7 3.3 6.9 13.8 12.1 13.0 9.8 6.0 12.0 11.9 12.9 5.9 18.1 7.8 31.9 10.0 20.9 11.3 10.8 6.4 12.8 4.9 5.3 14.8 5.0 14.8 8.9 13.2 15.3 4.6 13.5 21.6 17.2 19.2 15.7 8.9 3.6 13.2 8.0 5.1 6.0 7.1 6.4 5.3 4.9 4.0 3.6 3.5 3.1 4.7 5.6 24.2 44.8 23.6 59.4 55.1 21.5 52.0 15.8 21.1 16.2 22.0 17.5 7.4 8.6 21.4 12.9 37.5 20.0 104.9 21.7 1.9 16.8 120.3 26.3 19.7 22.7 15.7 17.5 196.9 16.5 6.6 20.4 11.2 60.7 31.6 29.6 20.3 9.6 12.5 30.3 123.1 15.2 8.2 32.5 24.6 12.7 13.7 34.3 12.4 94.6 19.8 15.3 68.0 112.1 94.4 31.8 21.7 14.3 94.9 53.4 10.4 9.1 15.5 50.7 6.6 26.4 27.2 28.2 15.3 17.5 27.4 13.1 88.3 4.6 18.7 62.5 RASGEF1B "FLJ31695, GPIG4" ENSG00000138670 "RasGEF domain family member 1B" Q0VAM2 4 81426393-82044244 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 118.7;granulocytes: 107.0;Langerhans cells: 282.6;Macrophages: 141.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 11.9;memory B-cell: 9.7;naive B-cell: 12.4;non-classical monocyte: 20.6;plasmacytoid DC: 28.0" "Group enriched" "Detected in all" 5 "B-cells: 12.4;dendritic cells: 28.0;monocytes: 20.6" "Cell line enhanced" "Detected in some" "CACO-2: 13.4;Daudi: 16.1;Karpas-707: 11.1;NTERA-2: 7.9;OE19: 9.2;SCLC-21H: 7.3;SuSa: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044574 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA044574: AB_10794292" "unprognostic (3.24e-1)" "prognostic favorable (6.40e-4)" "unprognostic (1.32e-1)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "prognostic favorable (1.49e-5)" "unprognostic (4.42e-2)" "unprognostic (6.31e-2)" "unprognostic (4.43e-1)" "unprognostic (4.85e-2)" "unprognostic (1.13e-2)" "unprognostic (3.88e-2)" "prognostic favorable (4.21e-6)" "unprognostic (4.19e-3)" "unprognostic (1.44e-2)" "unprognostic (3.19e-2)" "unprognostic (6.04e-2)" 13.8 6.4 8.9 11.0 20.1 32.5 8.3 12.8 9.4 8.8 17.0 6.5 13.6 3.5 12.3 11.3 8.0 12.0 4.3 8.0 9.3 9.4 41.8 19.8 10.7 37.6 12.5 2.5 2.8 5.4 7.5 13.0 39.0 4.2 7.1 12.5 9.9 2.1 2.9 24.3 13.9 5.9 10.0 11.2 14.7 2.4 18.4 14.2 3.4 2.3 9.8 6.0 5.3 20.2 0.0 0.0 0.1 0.0 0.2 0.0 1.1 0.1 0.0 0.0 0.0 13.4 0.3 16.1 0.0 0.0 0.1 0.3 1.1 0.1 0.0 0.1 2.5 1.4 1.0 0.6 0.5 0.3 0.7 0.2 0.6 0.0 0.5 0.1 0.0 2.8 0.2 11.1 0.0 0.6 5.5 0.5 7.9 9.2 3.6 1.6 0.1 6.4 0.5 0.2 7.3 0.1 0.0 2.3 0.1 7.3 1.1 0.0 0.0 0.0 0.5 0.5 0.1 0.1 0.0 5.1 1.2 0.2 0.2 0.8 3.0 0.4 1.9 11.9 2.1 9.7 1.6 1.6 2.7 12.4 2.8 2.7 1.1 3.8 20.6 28.0 0.5 1.2 8.9 20.1 12.8 9.4 8.0 9.3 37.6 12.5 39.0 10.0 18.4 20.2 9.6 28.9 15.9 1.3 118.7 58.9 7.9 4.4 23.9 11.7 22.7 13.2 9.1 15.7 11.1 14.7 37.5 33.2 71.2 13.2 13.7 3.1 0.5 44.5 4.8 10.8 26.8 0.0 3.6 4.0 2.4 9.1 30.1 38.0 107.0 0.6 102.1 45.9 39.5 3.3 2.8 12.8 16.2 64.2 282.6 1.5 0.9 141.4 62.2 10.3 2.9 1.0 2.1 26.7 25.5 3.0 9.6 1.9 33.5 10.2 9.2 12.9 34.0 4.9 0.0 5.9 17.7 0.8 3.2 10.4 56.7 11.2 56.3 0.5 8.1 11.5 RASSF3 ENSG00000153179 "Ras association domain family member 3" Q86WH2 12 64507001-64697564 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 149.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 124.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 124.1" "Cell line enhanced" "Detected in all" "SK-MEL-30: 145.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022664, CAB034035, HPA038469" Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB022664: , CAB034035: AB_2176848, HPA038469: AB_10671743" "unprognostic (1.63e-1)" "unprognostic (1.33e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (2.37e-2)" "unprognostic (2.55e-3)" "unprognostic (3.73e-1)" "unprognostic (2.37e-1)" "unprognostic (6.21e-2)" "unprognostic (3.66e-2)" "unprognostic (1.49e-1)" "unprognostic (1.45e-3)" "unprognostic (7.16e-2)" "unprognostic (2.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.59e-2)" 33.1 22.9 13.8 43.3 9.3 17.3 14.9 7.1 9.5 19.4 33.0 106.6 21.1 23.9 15.1 36.8 13.2 29.3 44.3 7.6 9.2 6.9 10.9 32.5 37.0 11.4 20.5 19.6 13.1 3.3 4.6 39.6 13.6 33.0 42.0 1.5 35.6 48.7 45.0 6.8 26.3 60.1 11.4 47.6 34.5 13.5 22.1 15.4 6.5 13.1 33.2 50.3 14.1 13.4 28.1 30.9 9.6 18.6 10.2 14.7 58.3 11.9 61.8 15.8 18.6 22.3 28.9 43.6 24.8 8.6 19.0 12.1 29.6 12.5 19.0 35.5 11.3 28.6 13.0 25.5 27.9 30.5 19.3 10.0 10.7 36.2 26.7 46.1 68.0 20.7 15.4 21.0 18.7 26.5 20.2 19.9 21.4 65.8 18.8 32.5 30.9 18.4 20.8 33.6 21.7 22.7 20.0 3.8 145.5 23.0 17.3 19.0 98.7 12.8 15.6 13.5 13.1 19.5 22.0 28.0 15.4 26.2 37.8 19.6 16.6 12.5 13.2 17.7 11.1 14.1 19.4 14.9 9.1 10.1 19.1 20.3 124.1 12.0 17.7 8.4 22.1 2.8 13.8 9.3 7.1 9.5 7.6 9.2 11.4 20.5 13.6 11.4 22.1 13.4 30.7 3.2 15.4 4.2 32.7 16.3 15.0 5.5 2.8 0.0 12.4 13.7 56.5 30.0 8.9 5.5 0.0 35.5 39.0 67.4 0.0 12.4 0.3 14.4 4.1 31.2 26.4 16.4 8.7 21.2 19.1 14.5 20.9 28.3 6.3 4.7 20.7 4.6 24.1 0.0 16.2 15.8 2.0 69.9 149.3 0.8 2.5 55.7 48.0 49.6 72.7 2.8 32.0 3.5 4.8 24.0 14.5 14.3 9.8 25.5 13.3 1.7 3.9 0.2 13.1 9.2 27.0 0.6 19.3 5.9 11.9 19.7 30.7 1.6 20.7 21.1 RB1 "OSRC, PPP1R130, RB" ENSG00000139687 "RB transcriptional corepressor 1" P06400 13 48303744-48599436 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 187.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000095, CAB016687, HPA050082" Supported Supported Nucleoplasm NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB000095: , CAB016687: AB_1622010, HPA050082: AB_2681008" "unprognostic (4.24e-3)" "unprognostic (1.00e-1)" "unprognostic (3.62e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-2)" "unprognostic (3.86e-1)" "unprognostic (4.69e-2)" "unprognostic (7.08e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (6.92e-4)" "unprognostic (4.06e-2)" "unprognostic (9.40e-2)" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (9.99e-2)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" 20.7 18.7 8.9 22.8 9.7 19.3 17.8 12.0 13.0 18.8 10.9 15.1 14.6 15.7 21.2 21.9 13.1 17.3 17.8 8.5 10.9 18.4 14.5 18.1 30.7 13.9 10.3 11.5 9.2 20.5 6.5 24.9 13.4 15.1 17.1 12.5 16.9 15.9 19.0 23.6 15.6 18.3 11.6 24.8 16.3 12.9 9.3 34.2 22.4 21.2 30.1 19.8 10.6 15.1 29.1 15.8 40.9 44.2 19.8 22.8 18.5 56.6 45.9 57.4 48.3 13.4 49.8 37.3 12.8 37.4 31.7 39.6 53.7 44.8 86.6 53.0 20.8 68.5 29.4 22.7 21.1 59.5 62.0 12.9 27.0 37.3 47.1 47.8 40.1 90.1 23.4 29.6 66.4 13.7 187.2 29.8 20.0 65.6 17.3 79.8 41.1 43.0 59.6 27.6 2.0 41.8 55.1 27.3 46.2 36.2 29.8 76.3 32.1 35.3 23.3 43.7 51.2 13.1 3.9 0.4 18.8 36.7 48.9 23.8 14.9 8.8 6.9 19.9 5.6 30.2 5.7 6.9 15.2 29.4 4.8 5.6 20.6 5.9 20.9 16.9 7.4 7.1 8.9 9.7 12.0 13.0 8.5 10.9 13.9 10.3 13.4 11.6 9.3 15.1 59.2 3.2 19.6 75.4 97.3 28.4 23.3 27.6 63.2 17.3 26.9 21.0 18.3 14.3 19.2 31.3 29.2 7.1 50.1 17.8 15.6 19.3 28.1 40.1 36.2 46.4 17.5 50.7 99.5 11.9 9.6 22.2 29.0 40.4 12.0 25.9 35.7 17.3 77.4 18.5 98.9 20.0 8.2 105.3 198.9 13.9 26.1 104.2 26.6 152.7 93.7 20.4 22.6 101.0 98.3 17.4 10.7 28.6 69.9 24.0 15.7 23.6 25.3 19.6 19.7 28.5 32.3 33.0 21.3 72.1 38.2 4.4 38.3 21.2 16.6 18.0 RBM23 "CAPERbeta, FLJ10482, RNPC4" ENSG00000100461 "RNA binding motif protein 23" Q86U06 14 22893204-22919182 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" HPA004144 Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Intermediate filaments" Nucleoplasm "HPA004144: AB_1079747" "unprognostic (5.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.48e-1)" "unprognostic (7.11e-2)" "unprognostic (1.11e-1)" "unprognostic (1.41e-2)" "unprognostic (2.14e-2)" "unprognostic (1.06e-1)" "unprognostic (4.27e-2)" "unprognostic (4.70e-2)" "unprognostic (3.73e-3)" "unprognostic (2.29e-1)" "prognostic favorable (8.06e-9)" "unprognostic (4.41e-2)" "unprognostic (3.06e-1)" "unprognostic (5.05e-2)" "unprognostic (1.81e-1)" 31.8 37.9 35.8 34.1 38.5 53.2 40.7 55.0 42.0 46.0 48.4 38.3 30.7 53.4 39.3 39.6 59.4 39.1 33.6 35.8 42.9 44.2 40.7 42.0 44.8 38.6 38.5 57.9 39.2 83.2 40.6 46.7 37.0 39.0 41.7 52.2 38.0 40.1 29.1 36.3 37.3 45.9 37.7 45.4 39.2 31.3 43.4 57.9 54.5 40.7 50.6 43.5 37.7 45.0 55.9 86.3 86.6 45.4 46.5 39.6 36.1 59.9 81.3 114.0 88.8 39.6 66.6 93.0 45.8 55.8 54.8 77.3 98.3 50.3 92.2 73.1 81.2 43.7 65.8 2.8 72.9 84.6 68.9 51.0 68.3 65.8 43.4 63.4 64.4 45.5 56.5 58.3 56.6 71.1 93.8 38.0 38.7 84.8 80.3 80.1 71.8 56.6 44.0 78.0 59.5 66.3 89.8 68.8 38.6 56.6 50.8 49.6 59.8 19.3 33.3 47.5 56.1 55.1 77.0 87.6 32.4 48.2 71.7 40.1 47.7 50.7 37.1 37.0 25.1 29.3 26.3 32.2 49.5 34.7 31.5 28.2 136.6 59.7 49.7 24.6 30.0 32.0 35.8 38.5 55.0 42.0 35.8 42.9 38.6 38.5 37.0 37.7 43.4 45.0 36.8 44.8 48.3 12.1 82.3 18.4 44.7 28.4 27.9 66.4 38.7 35.9 24.3 68.6 42.7 33.1 116.7 53.0 53.8 48.8 45.0 36.3 9.5 55.1 36.8 39.5 65.4 54.1 13.5 33.5 48.0 32.0 36.7 41.4 70.9 27.2 53.2 37.2 31.5 50.5 16.1 39.3 20.3 54.9 33.6 11.9 35.4 40.4 16.0 19.7 70.8 52.4 102.0 18.6 15.3 39.7 55.1 28.2 42.2 29.1 57.3 33.1 64.0 164.2 32.9 47.8 32.1 52.0 64.3 22.0 21.0 101.4 64.0 28.1 42.3 27.8 RBM3 IS1-RNPL ENSG00000102317 "RNA binding motif protein 3" P98179 X 48574449-48581162 "Predicted intracellular proteins" "Stress response" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 1442.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "HPA003624, CAB062559" Enhanced Enhanced Nucleoplasm NA NA 130000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "CAB062559: AB_2665621, HPA003624: AB_10602123" "unprognostic (1.07e-2)" "unprognostic (1.14e-3)" "prognostic favorable (3.07e-7)" "unprognostic (1.65e-3)" "unprognostic (2.87e-1)" "unprognostic (4.05e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (9.37e-2)" "unprognostic (1.63e-2)" "unprognostic (2.65e-2)" "unprognostic (2.02e-2)" "unprognostic (6.18e-2)" "unprognostic (1.10e-1)" "unprognostic (5.05e-2)" "unprognostic (3.92e-2)" "unprognostic (1.59e-1)" 246.8 129.7 21.7 143.2 23.7 301.8 200.9 23.0 33.2 82.3 27.5 122.4 102.1 118.2 89.4 147.1 101.7 71.9 100.7 22.3 27.9 89.2 71.1 130.5 158.5 27.9 24.0 99.3 167.2 94.2 80.1 104.0 26.5 75.7 146.0 51.4 126.0 81.8 112.3 195.3 102.6 114.9 28.7 128.5 114.2 55.9 23.4 156.9 90.1 38.3 206.1 135.0 101.7 29.3 128.2 168.7 172.5 187.3 42.4 226.3 117.2 156.0 272.3 381.6 273.6 173.7 322.5 241.4 50.0 302.3 75.9 107.1 153.2 209.1 304.1 236.5 206.7 126.2 270.5 164.0 153.0 360.8 248.0 168.1 143.8 129.7 124.3 46.2 320.4 131.7 69.8 194.6 268.6 215.9 304.9 209.3 100.5 33.3 230.1 280.7 181.4 196.5 177.7 201.8 70.1 179.1 152.2 206.9 187.5 83.7 272.2 363.6 440.7 127.0 213.0 425.8 278.2 93.7 114.0 279.1 176.5 208.0 263.0 33.0 187.0 30.7 118.4 211.9 141.7 147.5 120.6 119.7 264.1 101.5 120.6 119.5 28.7 150.9 187.0 185.0 137.5 256.3 21.7 23.7 23.0 33.2 22.3 27.9 27.9 24.0 26.5 28.7 23.4 29.3 336.2 166.7 172.1 18.6 391.7 519.4 182.9 379.4 157.6 58.9 326.1 260.5 76.8 154.4 196.7 53.3 47.9 459.9 392.1 165.8 176.1 482.2 6.0 114.6 193.8 292.9 247.4 287.0 18.4 1442.0 726.9 274.2 164.1 234.3 265.2 144.9 195.9 74.6 433.2 42.1 17.7 360.2 136.3 439.5 783.6 17.1 245.7 339.3 522.9 18.7 571.7 181.8 358.4 15.1 18.0 915.3 235.9 147.4 317.7 119.0 143.3 164.3 84.6 87.0 131.5 378.4 299.4 43.6 200.8 285.2 507.8 489.3 352.5 178.2 368.0 202.6 RBM33 "DKFZp434D1319, DKFZp686F102, MGC20460, PRR8" ENSG00000184863 "RNA binding motif protein 33" Q96EV2 7 155644451-155781485 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019232, HPA021497, HPA021768" Approved Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA019232: AB_1856121, HPA021497: AB_2176261, HPA021768: AB_1856123" "unprognostic (1.35e-2)" "unprognostic (1.99e-1)" "unprognostic (1.11e-1)" "unprognostic (3.04e-2)" "unprognostic (2.06e-1)" "prognostic favorable (9.63e-5)" "unprognostic (3.48e-2)" "unprognostic (2.07e-2)" "unprognostic (6.85e-2)" "unprognostic (3.89e-2)" "unprognostic (8.90e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.98e-1)" "unprognostic (2.42e-1)" "unprognostic (4.46e-2)" "prognostic favorable (4.29e-4)" 25.4 19.3 14.4 15.2 14.4 62.2 23.3 39.8 18.9 26.8 6.7 24.8 14.0 22.3 17.1 24.3 20.5 8.8 20.1 11.9 20.3 22.7 32.1 30.1 18.8 16.6 11.6 26.1 30.1 8.1 28.3 10.6 14.7 23.0 12.7 33.7 23.0 9.4 30.9 30.5 31.1 9.5 3.7 30.2 26.9 16.9 16.7 31.5 24.5 10.1 15.6 19.4 28.2 23.8 31.9 37.0 22.7 21.1 12.0 15.6 22.9 19.8 14.0 12.0 17.3 34.2 30.0 35.1 25.9 14.7 32.5 22.5 20.8 16.7 15.9 33.3 29.0 33.5 41.7 22.7 13.2 47.7 32.5 15.3 19.3 19.2 27.3 17.4 21.4 38.8 43.6 28.3 17.2 31.1 49.4 40.8 24.4 21.4 23.3 39.2 25.4 29.4 17.4 34.1 23.0 23.5 33.2 21.7 18.0 17.0 16.6 24.8 24.8 20.2 11.9 36.6 26.6 48.8 40.7 52.4 32.7 30.5 26.4 33.5 10.4 23.1 6.6 10.5 5.4 9.5 6.6 8.2 9.1 7.7 6.1 7.8 37.2 9.1 8.3 9.0 9.3 4.2 14.4 14.4 39.8 18.9 11.9 20.3 16.6 11.6 14.7 3.7 16.7 23.8 36.3 32.1 36.4 68.2 52.3 19.6 20.4 19.7 33.6 57.6 22.2 19.8 30.2 14.3 17.0 3.7 83.4 18.1 60.3 32.4 7.9 20.1 25.6 25.9 43.7 27.6 26.3 37.2 86.8 18.0 17.4 26.0 45.3 43.0 39.2 38.9 17.5 30.0 15.9 132.9 85.5 28.1 16.2 28.3 24.4 42.0 26.1 39.3 12.4 87.1 42.9 23.0 42.2 97.0 115.0 23.5 28.5 17.7 93.1 33.3 37.1 18.2 19.2 91.5 13.1 37.5 31.5 29.5 24.4 26.3 23.4 26.1 53.0 33.9 24.0 36.5 RBP3 "D10S64, D10S65, D10S66, RP66" ENSG00000265203 "Retinol binding protein 3" P10745 10 47348363-47357881 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transport "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 335 "retina: 542.3" "Group enriched" "Detected in some" 11 "Cone photoreceptor cells: 2070.4;Rod photoreceptor cells: 1610.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Low region specificity" "Detected in many" "HPA041301, HPA044239" Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA041301: AB_2677398, HPA044239: AB_2678868" "unprognostic (3.48e-2)" "unprognostic (4.78e-3)" "unprognostic (1.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.40e-1)" "unprognostic (1.58e-2)" "unprognostic (5.09e-2)" "unprognostic (5.14e-3)" "unprognostic (7.44e-2)" "unprognostic (1.23e-1)" "unprognostic (4.68e-3)" 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.1 0.3 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 542.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.3 1.2 1.6 0.5 0.3 0.6 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.7 0.0 0.0 0.5 0.0 0.0 0.0 2070.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 43.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1610.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 11920.3" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 12711.6" "Cancer enriched" "Detected in all" 27 "liver cancer: 3135.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 1117.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001641, CAB004555" Supported "Secreted to blood" NA NA 46100000000 210000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB004555: AB_670938, HPA001641: AB_1079795" "unprognostic (9.42e-3)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.60e-2)" "unprognostic (6.69e-4)" "prognostic favorable (1.74e-8)" "unprognostic (2.39e-1)" "unprognostic (5.76e-2)" "unprognostic (3.26e-2)" "unprognostic (3.26e-1)" "unprognostic (3.44e-1)" "unprognostic (7.14e-3)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" 730.7 32.4 30.2 6.2 34.4 1.1 394.2 12.4 48.1 5.8 12.4 11.2 4.8 2.3 0.9 1.1 2.1 7.5 16.7 32.2 113.0 142.8 11920.3 24.5 0.6 21.5 19.3 4.1 82.4 0.1 519.9 12.4 21.3 8.6 6.7 3.0 13.7 4.6 6.2 16.4 19.2 0.8 14.9 5.5 11.9 4.7 46.2 1.5 7.9 5.3 0.1 19.0 8.8 18.0 0.0 14.7 0.0 0.0 2.9 0.0 0.1 0.3 0.1 2.5 0.4 264.9 0.5 1.5 2.7 0.3 0.2 0.8 0.0 0.0 0.3 0.2 0.2 2.2 1.1 1117.2 0.2 9.2 0.2 18.7 0.5 0.7 0.0 0.0 0.0 0.0 1.4 0.2 1.2 0.0 0.1 7.3 1.3 2.4 121.7 0.4 7.0 0.0 0.0 0.6 0.9 0.2 9.6 0.0 0.0 0.6 0.5 0.8 0.4 0.0 7.8 0.2 0.3 0.9 0.3 3.7 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 34.4 12.4 48.1 32.2 113.0 21.5 19.3 21.3 14.9 46.2 18.0 9.1 0.0 4.2 0.3 17.2 0.8 0.5 0.0 0.0 0.0 2.1 6.7 0.7 999.4 0.6 23.9 6.2 0.3 0.2 21.9 97.8 7.8 2.8 1.6 3.1 10.8 62.5 152.4 5.8 0.2 22.6 10.5 0.0 22.1 0.0 0.0 158.1 12711.6 17.8 0.0 7.2 40.7 0.0 210.4 3.0 2.4 3.1 7.8 1.8 1.0 0.0 0.8 0.0 1.0 1.1 29.2 28.0 5.7 0.3 2.1 0.8 785.3 0.7 0.5 0.0 7.3 3.8 3.1 13.9 0.0 0.9 1.4 12.3 0.0 1.7 1.4 RCN1 "FLJ37041, PIG20, Rcal, RCN" ENSG00000049449 "Reticulocalbin 1" Q15293 11 32091074-32105722 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "epididymis: 660.2" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 288.2;Muller glia cells: 327.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA038474, HPA062104" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 9400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA038474: AB_10672595, HPA062104: AB_2684683" "unprognostic (1.65e-1)" "unprognostic (7.69e-3)" "unprognostic (1.24e-1)" "unprognostic (2.03e-2)" "unprognostic (7.20e-3)" "unprognostic (1.70e-2)" "unprognostic (6.92e-3)" "prognostic unfavorable (7.13e-6)" "unprognostic (8.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.12e-1)" "unprognostic (9.32e-2)" "prognostic unfavorable (2.70e-13)" "unprognostic (1.78e-2)" "unprognostic (2.04e-1)" "unprognostic (1.14e-1)" "unprognostic (6.93e-3)" 81.8 54.4 26.7 58.3 39.6 8.1 64.6 24.0 28.2 73.9 37.2 54.7 43.4 79.7 660.2 25.7 69.5 50.1 46.0 26.4 37.2 39.2 100.7 50.6 29.2 29.9 27.6 83.6 21.9 62.2 67.3 129.0 29.0 85.6 53.7 48.7 89.9 82.5 32.7 26.8 41.5 79.5 31.8 35.9 40.7 22.5 36.7 19.0 63.4 28.8 23.1 113.1 41.1 31.3 130.0 143.7 335.9 217.4 720.2 548.1 340.4 425.5 501.5 286.6 515.6 123.6 157.2 0.4 293.3 718.4 380.4 157.6 118.0 135.2 450.2 63.9 231.9 28.2 104.7 58.4 519.7 21.7 42.0 780.1 154.8 197.1 215.4 333.7 647.7 60.6 17.4 25.8 342.1 116.0 61.4 50.2 137.2 2.7 143.9 45.1 393.5 39.2 270.1 355.8 82.1 42.6 117.1 26.2 333.1 227.2 171.0 77.5 350.8 417.0 215.8 338.5 364.6 1.0 0.9 1.7 514.2 28.3 224.9 0.3 13.6 0.5 14.9 16.2 11.8 6.2 6.9 12.3 15.2 4.8 5.1 9.5 0.6 10.9 10.3 8.2 2.7 9.3 26.7 39.6 24.0 28.2 26.4 37.2 29.9 27.6 29.0 31.8 36.7 31.3 131.3 54.5 34.8 9.8 11.8 41.6 80.8 78.2 34.1 40.4 47.9 37.5 9.0 42.9 55.1 47.8 12.5 172.6 10.5 14.3 7.9 143.4 210.4 60.7 154.9 112.1 53.2 16.4 8.0 45.7 288.2 152.1 23.0 110.2 12.7 100.3 85.3 61.7 44.2 15.2 5.9 80.9 38.7 17.8 33.9 173.8 80.5 19.9 32.0 8.4 50.3 327.4 19.6 16.6 1.3 39.7 30.8 73.0 38.6 184.9 6.7 14.1 30.4 17.0 26.3 80.8 91.7 17.0 7.2 33.2 28.3 217.0 13.6 55.8 75.3 99.8 RCN2 "E6BP, ERC-55, ERC55, TCBP49" ENSG00000117906 "Reticulocalbin 2" Q14257 15 76931738-76954393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 321.5" "Cell type enhanced" "Detected in all" "Spermatocytes: 528.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030694, HPA030695" Enhanced Supported Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 92000 "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Endoplasmic reticulum" "HPA030694: AB_2673573, HPA030695: AB_2673574" "unprognostic (1.69e-2)" "unprognostic (1.79e-1)" "unprognostic (1.92e-2)" "unprognostic (3.45e-2)" "unprognostic (2.42e-1)" "unprognostic (8.71e-2)" "prognostic unfavorable (7.36e-5)" "unprognostic (1.74e-1)" "unprognostic (2.20e-2)" "unprognostic (4.61e-3)" "unprognostic (1.39e-1)" "unprognostic (1.98e-1)" "unprognostic (1.70e-2)" "unprognostic (2.11e-2)" "unprognostic (2.99e-1)" "unprognostic (1.15e-1)" "unprognostic (3.67e-2)" 31.3 30.8 42.5 24.9 43.9 24.6 35.8 35.8 57.8 34.1 41.4 33.1 22.2 44.0 321.5 28.5 54.3 32.6 38.8 44.0 55.0 49.3 19.8 28.8 30.0 38.0 45.1 34.2 21.5 80.6 30.8 49.2 46.9 41.2 36.5 43.9 22.7 41.1 56.9 22.6 23.3 39.6 40.0 25.4 26.9 93.4 51.4 40.3 48.0 60.4 32.4 39.0 25.2 40.8 93.9 65.3 284.1 134.9 120.1 135.6 177.3 109.1 147.5 138.7 115.1 81.2 78.2 58.3 154.3 119.3 149.5 139.9 217.4 94.0 176.0 45.3 170.8 28.9 91.4 135.0 143.0 105.4 42.9 123.6 126.8 68.2 87.5 146.1 148.9 98.3 74.2 56.3 146.6 60.3 104.9 71.9 216.6 98.0 72.1 109.4 187.0 37.3 91.6 123.8 161.8 161.1 178.8 98.6 220.5 251.1 96.0 115.0 80.5 162.8 131.2 104.8 228.0 80.4 266.6 69.6 92.8 87.6 151.1 7.5 7.6 16.2 21.7 7.4 24.9 23.4 23.0 28.1 16.1 22.9 25.5 25.1 3.9 23.5 12.3 19.1 18.1 20.0 42.5 43.9 35.8 57.8 44.0 55.0 38.0 45.1 46.9 40.0 51.4 40.8 87.3 25.6 36.8 56.8 111.2 82.1 125.0 85.5 96.2 87.1 75.9 74.8 94.9 62.9 52.5 99.3 37.5 183.1 76.3 23.3 49.0 116.0 44.8 87.0 101.6 64.8 73.5 91.5 48.4 45.1 296.8 106.0 54.6 85.6 28.6 120.9 60.0 32.8 57.3 127.9 72.0 55.0 101.7 30.5 38.3 81.7 61.8 30.0 92.5 19.7 34.1 99.7 89.6 149.8 63.3 56.9 43.2 93.6 85.6 127.5 25.8 56.2 48.7 58.9 59.2 78.9 126.3 528.6 140.8 109.3 70.8 163.6 76.7 131.8 84.4 117.0 RCN3 RLP49 ENSG00000142552 "Reticulocalbin 3" Q96D15 19 49528003-49546962 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 54.7;Fibroblasts: 105.1;Leydig cells: 38.2;Peritubular cells: 44.8;Smooth muscle cells: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 6.8" "Group enriched" "Detected in many" 9 "granulocytes: 2.5;NK-cells: 1.8;T-cells: 6.8" "Cell line enhanced" "Detected in many" "AN3-CA: 166.6;ASC diff: 283.3;ASC TERT1: 175.4;BJ: 353.8;BJ hTERT+ SV40 Large T+ RasG12V: 179.6;fHDF/TERT166: 304.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043134, HPA050402" Uncertain Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" No No 1600000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA043134: AB_2678332, HPA050402: AB_2681114" "unprognostic (7.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.77e-3)" "unprognostic (8.87e-2)" "unprognostic (3.36e-3)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (1.16e-1)" "unprognostic (7.47e-2)" "unprognostic (9.75e-2)" "unprognostic (2.85e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (5.80e-12)" "unprognostic (5.26e-2)" "unprognostic (3.90e-2)" "unprognostic (1.56e-2)" "unprognostic (4.20e-3)" 67.9 35.3 15.8 33.6 17.2 6.8 48.2 15.5 24.1 78.8 23.5 43.5 39.9 47.4 4.4 11.4 41.4 25.2 56.7 16.0 19.1 41.2 62.3 40.8 8.7 17.4 17.0 50.0 16.4 3.9 20.7 31.1 19.0 32.4 11.4 1.4 19.1 12.1 11.7 25.3 43.2 25.7 16.8 65.9 23.4 17.2 24.5 4.0 26.4 7.5 4.1 43.2 46.3 18.8 3.2 4.3 2.7 166.6 283.3 175.4 1.9 353.8 86.5 122.0 179.6 4.2 1.3 1.3 19.5 304.0 1.3 0.3 6.8 0.5 49.2 0.1 2.5 19.5 1.5 9.1 105.7 0.1 43.0 119.5 0.2 93.2 0.4 3.2 43.8 2.3 8.7 1.0 87.8 2.9 0.1 2.0 1.4 8.8 24.5 0.5 3.9 4.0 1.4 0.0 1.7 10.5 0.3 1.1 0.3 2.8 1.3 11.5 121.4 1.7 52.4 135.3 0.1 14.9 44.5 2.6 7.9 9.6 13.4 0.0 0.2 1.6 0.7 0.0 0.7 0.4 1.7 0.6 0.4 0.2 6.8 2.3 2.5 1.8 0.3 0.2 1.6 1.1 15.8 17.2 15.5 24.1 16.0 19.1 17.4 17.0 19.0 16.8 24.5 18.8 12.0 0.0 6.1 4.6 2.8 18.6 0.6 2.9 3.4 0.8 1.7 3.3 2.1 1.5 0.8 1.8 0.0 2.5 1.4 10.5 1.9 1.6 2.2 1.5 54.7 10.6 1.2 0.0 1.0 0.5 5.0 105.1 6.6 1.6 1.3 7.0 27.1 3.7 22.6 1.7 1.1 7.6 0.0 11.4 23.2 3.0 38.2 11.9 10.6 10.3 3.1 0.6 0.0 1.5 0.8 1.5 7.9 44.8 4.8 0.9 13.1 0.6 0.9 0.8 13.1 37.5 66.5 6.5 6.8 2.8 13.9 6.2 2.2 17.2 8.0 0.4 RCOR1 "COREST, KIAA0071, RCOR" ENSG00000089902 "REST corepressor 1" Q9UKL0 14 102592649-102730561 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 117.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001956, HPA049327, HPA054241" Supported Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB001956: , HPA049327: AB_2680715, HPA054241: AB_2682426" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.17e-1)" "unprognostic (4.01e-3)" "unprognostic (1.25e-1)" "unprognostic (2.18e-1)" "unprognostic (9.96e-3)" "unprognostic (1.72e-2)" "unprognostic (1.87e-2)" "unprognostic (4.98e-2)" "unprognostic (1.46e-2)" "unprognostic (6.05e-3)" "unprognostic (7.23e-2)" "unprognostic (1.39e-1)" "unprognostic (2.02e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (3.72e-4)" 11.2 5.8 3.3 11.2 3.1 46.1 9.0 4.6 4.1 14.2 3.3 11.0 12.0 9.5 13.3 33.2 9.5 8.7 6.7 5.0 3.6 6.7 9.4 12.9 11.9 3.4 3.5 9.0 7.9 10.4 5.2 20.8 3.6 8.8 11.1 6.3 10.2 5.8 11.8 16.6 12.6 8.8 3.5 8.6 13.4 13.7 4.3 14.5 6.3 10.6 14.7 10.2 19.1 4.2 21.3 19.5 17.2 19.0 13.5 18.6 36.1 21.5 15.2 19.7 18.7 18.0 25.2 23.8 17.1 18.7 9.9 32.6 26.2 15.4 29.4 10.1 9.6 44.2 17.4 17.6 18.4 44.3 38.2 13.1 23.6 17.4 26.5 21.1 21.8 22.1 35.7 17.5 20.1 34.6 27.8 29.9 8.5 23.2 33.1 70.4 17.4 10.6 24.1 25.9 22.2 13.8 48.1 21.9 13.9 21.5 30.0 34.6 23.8 13.6 10.2 43.8 14.2 12.9 16.6 25.0 16.3 32.0 14.6 3.1 1.4 2.2 0.2 1.5 0.3 0.3 0.3 0.6 1.5 0.3 0.3 0.3 3.7 0.7 1.8 0.6 0.5 0.5 3.3 3.1 4.6 4.1 5.0 3.6 3.4 3.5 3.6 3.5 4.3 4.2 15.8 48.1 40.0 32.3 27.3 57.6 27.7 12.0 30.7 8.4 25.6 20.7 16.7 10.0 19.7 3.7 2.1 31.1 39.1 31.5 5.9 6.7 5.1 55.7 36.1 15.9 21.0 32.2 39.3 7.4 20.4 20.2 32.6 58.3 24.1 18.0 11.0 11.7 15.1 10.1 33.8 16.8 10.2 38.8 65.6 4.9 24.2 43.6 24.9 52.5 33.1 9.5 12.3 22.1 23.5 16.7 15.2 21.1 14.8 25.4 18.2 8.0 16.3 5.4 0.0 18.9 19.6 22.5 18.6 46.9 117.6 43.1 26.2 20.3 22.8 72.3 RDH10 SDR16C4 ENSG00000121039 "Retinol dehydrogenase 10" Q8IZV5 8 73294602-73325281 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Club cells: 131.7;Collecting duct cells: 204.1;Muller glia cells: 342.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 143.6;BJ: 107.4;CACO-2: 97.0;HDLM-2: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049199 Supported "Lipid droplets" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" "Lipid droplets" "HPA049199: AB_2680673" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (2.52e-1)" "unprognostic (2.45e-2)" "unprognostic (1.13e-2)" "unprognostic (1.14e-1)" "unprognostic (2.80e-2)" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.18e-3)" "unprognostic (8.88e-3)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (1.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.23e-2)" 43.3 6.2 4.2 23.4 5.3 3.3 10.5 4.1 4.1 18.2 16.0 16.6 32.4 14.1 3.9 19.8 7.8 30.2 11.6 4.9 5.9 43.8 41.0 13.6 11.0 11.5 6.8 5.0 34.5 8.4 26.8 36.3 6.4 21.5 15.2 86.3 39.2 13.1 6.9 8.3 30.7 14.9 5.8 7.2 24.8 16.6 20.4 6.1 6.5 8.2 8.8 69.2 11.3 6.7 13.8 39.2 4.3 17.9 143.6 10.5 39.0 107.4 17.4 4.1 6.8 97.0 38.6 9.6 13.9 60.4 6.3 35.6 19.6 15.5 8.4 110.7 49.0 17.0 37.6 30.1 5.6 8.2 18.0 6.3 19.6 16.5 15.3 18.3 15.6 9.4 20.0 13.7 7.0 6.1 8.5 3.4 5.2 84.0 19.0 7.4 4.4 5.8 28.2 19.4 2.6 3.4 9.1 66.3 5.5 5.4 13.1 4.2 24.0 6.3 10.6 28.9 8.3 8.8 10.0 7.8 5.0 7.3 14.7 1.2 0.1 0.2 0.3 0.1 0.2 0.1 0.3 0.4 0.2 0.0 0.6 0.3 0.1 0.0 0.1 0.0 0.2 0.1 4.2 5.3 4.1 4.1 4.9 5.9 11.5 6.8 6.4 5.8 20.4 6.7 14.5 12.8 29.8 3.6 2.5 13.5 9.7 75.6 16.5 3.2 29.1 25.5 9.1 25.8 131.7 204.1 22.9 19.1 11.2 25.5 3.9 16.3 80.6 38.3 50.0 9.7 4.2 1.3 1.4 17.6 23.8 44.6 49.5 71.5 2.5 1.2 3.3 49.2 20.9 3.3 1.0 16.8 40.7 5.4 7.8 9.9 2.8 10.0 17.8 6.5 1.9 342.1 3.1 4.5 2.0 56.9 31.5 3.8 6.4 41.2 47.7 22.6 44.2 16.2 0.0 11.4 20.5 11.0 8.0 24.7 13.9 42.0 7.1 1.6 24.2 17.7 RDH11 "ARSDR1, MDT1, SDR7C1" ENSG00000072042 "Retinol dehydrogenase 11" Q8TC12 14 67676800-67695793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cataract, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 582.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 241.8;Muller glia cells: 299.7;Prostatic glandular cells: 285.7" "Cancer enriched" "Detected in all" 13 "prostate cancer: 286.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046011 Enhanced "Intracellular and membrane" NA NA 340000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "CAB046011: AB_11129613" "unprognostic (1.38e-1)" "unprognostic (6.86e-3)" "unprognostic (1.77e-1)" "prognostic favorable (2.62e-4)" "unprognostic (6.06e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (9.29e-2)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.58e-2)" "unprognostic (2.91e-2)" "unprognostic (1.27e-1)" "prognostic favorable (1.30e-7)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (4.74e-2)" 23.6 59.5 39.3 24.5 43.2 13.9 28.7 50.2 54.4 32.6 35.9 29.2 34.1 33.2 86.0 34.6 23.5 42.7 17.6 40.4 47.2 106.0 153.1 34.9 20.4 49.2 47.7 28.9 42.6 79.8 23.4 21.9 49.3 582.0 31.4 73.9 44.2 34.4 8.3 31.4 23.9 43.6 49.8 22.2 31.9 28.4 46.1 30.7 61.7 13.5 26.2 34.3 30.3 58.4 183.7 81.9 71.3 82.0 111.5 100.4 59.3 68.0 134.2 83.7 150.9 68.6 216.7 31.7 51.2 64.6 104.8 142.5 104.0 150.8 113.7 63.0 42.6 65.1 40.7 69.0 106.9 24.3 46.0 94.4 98.0 109.3 92.0 63.9 97.4 87.0 52.1 101.1 77.2 97.5 72.2 38.8 40.4 49.7 92.8 53.6 87.4 45.8 194.1 93.0 73.8 62.0 71.2 89.7 99.1 58.2 100.7 38.3 74.2 89.5 101.1 38.9 49.5 47.5 40.0 40.7 115.8 66.0 74.3 282.4 71.1 104.0 62.3 57.7 68.2 39.0 67.7 61.5 51.3 45.5 67.3 64.8 11.0 56.3 65.4 59.1 65.1 115.8 39.3 43.2 50.2 54.4 40.4 47.2 49.2 47.7 49.3 49.8 46.1 58.4 27.0 25.6 66.0 38.2 29.2 11.5 40.0 77.9 16.5 53.5 45.4 24.5 20.4 68.6 59.9 47.8 50.1 24.9 32.4 26.8 7.9 92.5 2.5 21.9 50.9 39.3 43.3 29.2 33.3 84.0 38.1 37.5 19.9 38.2 29.2 46.3 47.8 241.8 35.8 79.1 37.6 28.9 89.5 42.4 15.4 6.1 43.2 35.9 35.6 17.8 39.8 299.7 37.0 70.4 43.4 61.2 36.7 56.1 27.3 285.7 17.5 56.0 23.9 97.0 46.0 29.7 38.7 25.8 24.0 20.2 19.2 63.5 29.8 66.7 25.3 46.1 RDH13 SDR7C3 ENSG00000160439 "Retinol dehydrogenase 13" Q8NBN7 19 55039108-55071291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 209.7;Urothelial cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 60.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042006 Approved Supported Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Mitochondria, Cytosol" "HPA042006: AB_10960270" "unprognostic (9.26e-2)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.15e-2)" "unprognostic (8.74e-2)" "unprognostic (1.08e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-2)" "unprognostic (1.82e-1)" "unprognostic (9.42e-3)" "unprognostic (1.61e-1)" "unprognostic (2.45e-3)" "prognostic favorable (2.09e-4)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (1.66e-3)" 4.5 4.8 2.5 3.4 2.6 2.2 4.5 3.9 3.6 9.4 3.9 8.6 6.7 4.2 0.7 19.8 4.8 3.0 13.0 2.4 3.5 9.2 8.2 4.4 3.5 3.5 4.2 3.7 8.6 12.4 6.4 10.1 3.7 6.3 3.8 2.1 9.6 3.7 9.7 21.0 6.1 2.0 1.6 6.2 10.5 5.3 3.8 2.2 7.5 4.8 2.7 5.1 12.2 2.3 10.9 12.3 2.9 10.3 1.5 3.0 17.9 3.4 2.1 3.7 6.4 23.3 15.7 9.4 5.3 1.2 2.7 14.1 7.8 7.2 1.7 7.3 60.0 12.2 9.8 14.6 2.9 12.4 8.0 2.6 6.3 3.0 2.9 3.7 3.0 5.2 27.2 2.9 2.3 13.4 6.1 9.6 2.5 17.7 25.7 15.7 6.7 27.6 8.2 37.3 8.8 6.2 8.9 31.3 7.0 2.7 12.0 9.3 3.0 0.3 3.7 0.1 8.2 7.8 11.0 9.6 9.1 10.6 6.6 3.8 4.1 4.1 8.2 6.3 7.7 5.4 6.3 7.6 4.2 5.8 8.4 6.1 1.9 7.8 5.0 6.4 5.5 3.0 2.5 2.6 3.9 3.6 2.4 3.5 3.5 4.2 3.7 1.6 3.8 2.3 8.9 16.0 13.1 3.9 6.6 10.7 31.7 11.1 7.4 21.0 12.2 9.9 27.5 20.0 19.3 14.7 41.7 41.3 9.4 47.2 11.7 13.5 24.3 18.3 8.8 9.1 12.0 4.2 9.4 6.5 29.0 7.1 46.4 31.8 8.2 24.4 18.5 7.3 11.5 25.2 10.0 27.5 12.2 4.9 5.0 13.2 3.7 4.2 7.2 4.7 5.0 9.0 6.2 5.0 2.9 14.5 35.7 3.4 8.7 30.6 20.3 4.8 12.8 25.3 6.6 5.1 6.5 3.2 8.9 11.1 17.5 209.7 9.2 11.1 28.1 110.1 RDH8 "PRRDH, SDR28C2" ENSG00000080511 "Retinol dehydrogenase 8" Q9NYR8 19 10013249-10022279 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "retina: 114.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 39.3;Cone photoreceptor cells: 54.2;Early spermatids: 72.6;Muller glia cells: 22.1;Rod photoreceptor cells: 203.4" "Cancer enriched" "Detected in some" 4 "melanoma: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA064473 Approved "Nucleoplasm,Midbody ring,Cytosol" Yes NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Midbody ring, Cytosol" "HPA064473: " "unprognostic (4.12e-1)" "unprognostic (2.22e-2)" "unprognostic (1.08e-1)" "unprognostic (9.98e-3)" "unprognostic (4.58e-3)" "unprognostic (2.66e-1)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "unprognostic (3.86e-1)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 114.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.3 0.0 0.0 0.2 0.0 0.0 0.0 54.2 0.0 0.0 0.0 0.0 0.0 72.6 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 203.4 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 REG1A "PSP, PSPS, PSPS1, PTP, REG" ENSG00000115386 "Regenerating family member 1 alpha" P05451 2 79120362-79123409 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 103906.5" "Cell type enriched" "Detected in some" 5 "Exocrine glandular cells: 115721.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 1268.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 12.3;EFO-21: 18.3;HDLM-2: 15.2;NB-4: 11.0;OE19: 10.7;RPMI-8226: 32.5;SH-SY5Y: 12.5;U-2 OS: 31.1;U-251 MG: 10.8;U-266/84: 13.3" "CAB025138, HPA045549, HPA045579" Enhanced "Secreted to digestive system" NA NA 68000000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "CAB025138: , HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (1.89e-1)" "unprognostic (2.91e-2)" "unprognostic (3.39e-1)" "unprognostic (1.45e-1)" "unprognostic (2.10e-1)" "unprognostic (1.63e-1)" "unprognostic (5.52e-2)" "unprognostic (3.54e-3)" "unprognostic (5.53e-2)" "unprognostic (5.54e-2)" 26.8 5.8 0.0 198.7 0.0 20.7 9.9 0.0 0.0 10.9 0.0 96.5 7597.3 5.3 0.0 9.3 6.4 96.6 10.2 0.0 0.0 93.0 15.9 4.5 7.5 0.0 0.0 25.6 103906.5 0.0 8.5 3.4 0.0 6.1 283.0 0.0 9.4 0.1 4.3 28.1 5638.4 178.1 0.0 8.5 945.9 3.9 0.0 0.0 4.0 0.0 0.4 3.2 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.5 10.7 0.0 0.0 0.0 32.5 0.0 0.0 1.4 12.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 31.1 2.0 10.8 0.0 13.3 5.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.2 0.0 0.0 0.0 0.0 0.0 25.5 1.9 1549.8 0.1 0.1 0.0 12.7 5.3 0.0 0.0 115721.8 0.0 0.9 692.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1813.1 0.0 0.0 0.0 0.1 0.0 17.0 0.0 0.0 507.5 0.0 0.0 0.0 0.0 22774.8 732.4 0.0 0.2 0.0 5100.1 20.8 0.0 0.0 0.0 0.0 51.7 0.0 0.4 0.0 0.0 0.0 0.6 0.0 5419.7 0.0 REG1B "PSPS2, REGH, REGI-BETA, REGL" ENSG00000172023 "Regenerating family member 1 beta" P48304 2 79085023-79088019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 39745.3" "Cell type enriched" "Detected in some" 4 "Exocrine glandular cells: 36125.0" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 201.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;HDLM-2: 4.1;RPMI-8226: 3.0;U-2 OS: 15.7;U-251 MG: 3.9;U-266/84: 3.8" "HPA045549, HPA045579" Supported "Secreted to digestive system" NA NA 32000000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (4.08e-1)" "unprognostic (1.09e-1)" "unprognostic (3.51e-3)" "unprognostic (9.20e-2)" 14.6 2.1 0.0 35.8 0.0 9.8 3.3 0.0 0.1 3.9 0.0 17.3 738.0 2.0 0.0 3.5 2.1 0.4 3.3 0.0 0.0 2.6 5.5 1.7 1.7 0.0 0.0 2.1 39745.3 0.0 3.1 0.1 0.0 2.0 108.1 0.0 3.1 0.0 1.6 16.1 2754.3 112.1 0.0 3.2 5.0 1.5 0.0 0.0 1.7 0.0 0.0 1.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.1 3.9 0.0 3.8 1.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 86.7 0.0 0.0 0.0 3.3 1.8 0.0 0.0 36125.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.6 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 178.3 0.0 0.0 0.0 0.0 7978.5 174.7 0.0 0.0 0.0 3101.3 0.1 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 178.8 0.0 REG3A "HIP, PAP, PAP1, PBCGF, REG-III, REG3" ENSG00000172016 "Regenerating family member 3 alpha" Q06141 2 79157003-79159753 "Plasma proteins, Predicted secreted proteins, Transporters" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 61 "intestine: 6743.6;pancreas: 12212.2" "Group enriched" "Detected in some" 11 "Exocrine glandular cells: 1988.6;Pancreatic endocrine cells: 5382.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 710.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 17.6;EFO-21: 15.8;HDLM-2: 15.4;NB-4: 17.7;RPMI-8226: 24.6;SH-SY5Y: 14.6;U-2 OS: 28.5;U-251 MG: 11.0;U-266/84: 15.1" "HPA047894, HPA048334, HPA060705" Supported Approved Cytosol "Secreted to digestive system" NA NA 23000000 "Cluster 25: Pancreas - Digestion" "Cluster 24: NB-4 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA047894: AB_2680202, HPA048334: AB_2680363, HPA060705: AB_2684346" "unprognostic (2.43e-2)" "unprognostic (2.12e-1)" "unprognostic (3.62e-2)" "unprognostic (1.42e-1)" 18.5 10.0 0.0 13.3 0.0 0.2 0.6 0.0 0.0 0.3 0.0 19.2 5180.0 2.9 0.0 1.4 0.2 24.9 1.0 0.0 0.0 2.6 2.0 0.5 4.9 0.0 0.0 0.9 12212.2 0.0 2.1 0.1 0.0 0.5 0.0 0.0 2.1 0.0 0.6 0.4 6743.6 0.2 0.0 1.3 156.5 0.9 0.0 0.0 0.6 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.1 0.4 0.0 0.0 0.0 24.6 0.0 0.0 1.8 14.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 28.5 5.4 11.0 0.0 15.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 152.8 7.7 0.0 0.0 3.0 0.0 0.0 0.0 1988.6 0.0 0.0 189.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.2 0.0 0.0 0.0 6.8 0.0 1.4 0.0 0.0 55.8 0.0 0.0 0.0 0.0 5382.1 32.5 0.0 0.2 0.0 215.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 315.9 0.0 REG3G "LPPM429, PAP1B, UNQ429" ENSG00000143954 "Regenerating family member 3 gamma" Q6UW15 2 79025686-79028505 "Predicted secreted proteins" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "pancreas: 3517.1" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 184.9;Pancreatic endocrine cells: 53.5;Proximal enterocytes: 39.4" "Cancer enriched" "Detected in many" 13 "pancreatic cancer: 71.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047894, HPA048334, HPA060705" Uncertain Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA047894: AB_2680202, HPA048334: AB_2680363, HPA060705: AB_2684346" "unprognostic (3.29e-1)" "unprognostic (2.20e-1)" "unprognostic (1.29e-1)" "unprognostic (8.82e-2)" "unprognostic (7.20e-3)" "unprognostic (5.64e-2)" 1.0 46.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.3 2.4 0.1 165.7 0.3 0.3 0.0 0.2 0.0 0.0 6.0 0.4 0.1 0.0 0.0 0.0 0.2 3517.1 0.0 0.3 1.1 0.0 0.1 0.0 0.0 0.3 1.3 0.2 0.1 37.0 1.5 0.0 0.2 0.4 57.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.7 0.0 0.0 0.1 0.0 0.0 0.0 184.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 6.2 0.6 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 53.5 0.0 0.7 0.0 0.4 39.4 2.2 0.0 0.0 0.0 0.0 0.2 1.3 1.2 0.0 0.0 0.0 0.0 0.9 5.4 0.0 REG4 "GISP, REG-IV, RELP" ENSG00000134193 "Regenerating family member 4" Q9BYZ8 1 119794017-119811580 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 662.5" "Cell type enriched" "Detected in some" 7 "Intestinal goblet cells: 3458.1" "Group enriched" "Detected in many" 21 "colorectal cancer: 180.6;pancreatic cancer: 215.1;stomach cancer: 162.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive CD8 T-cell: 24.6" "Lineage enriched" "Detected in single" 101 "T-cells: 24.6" "Cell line enriched" "Detected in some" 60 "OE19: 6164.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025867, HPA046555" Enhanced "Secreted to digestive system" NA NA 460000 "Cluster 32: T-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB025867: , HPA046555: AB_2679696" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (2.86e-3)" "unprognostic (2.57e-1)" "unprognostic (6.52e-2)" "unprognostic (6.20e-3)" "unprognostic (1.11e-1)" "unprognostic (1.64e-2)" "unprognostic (7.10e-2)" "unprognostic (7.85e-2)" "unprognostic (2.99e-1)" "unprognostic (5.12e-3)" "unprognostic (8.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-3)" 0.7 0.0 0.0 34.4 0.1 0.3 0.0 0.1 0.2 0.4 0.1 236.2 264.5 0.5 0.0 1.5 0.0 0.5 0.0 0.1 0.1 0.7 0.3 0.0 1.6 0.1 0.1 0.0 133.7 0.0 0.0 0.0 0.2 2.6 314.0 0.0 2.3 0.2 0.0 0.0 662.5 8.5 0.0 0.2 19.0 2.4 0.1 0.4 0.0 0.0 0.8 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.3 2.3 0.1 6164.0 102.7 0.0 0.0 0.8 0.0 29.2 0.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 3.8 24.6 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 10.8 0.0 0.0 0.0 441.8 0.0 0.0 1.0 0.0 0.0 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3458.1 0.0 0.0 0.0 25.9 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 140.0 0.0 0.1 3.8 178.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 2.9 0.1 52.0 0.2 RELN "PRO1598, RL" ENSG00000189056 Reelin P78509 7 103471381-103989658 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein, Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 64.4" "Group enriched" "Detected in some" 8 "Hepatic stellate cells: 128.5;Inhibitory neurons: 372.4" "Cancer enhanced" "Detected in many" "liver cancer: 5.7" "Region enriched" "Detected in many" 10 "cerebellum: 64.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 16.2;PC-3: 8.6;SCLC-21H: 11.1;SH-SY5Y: 13.7;TIME: 33.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 110.0" HPA077891 Approved "Golgi apparatus,Vesicles" "Secreted in brain" NA NA 30000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Vesicles "HPA077891: " "unprognostic (1.42e-1)" "unprognostic (2.93e-3)" "unprognostic (4.31e-2)" "unprognostic (1.29e-4)" "unprognostic (1.30e-1)" "unprognostic (6.95e-2)" "unprognostic (1.85e-1)" "unprognostic (8.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.48e-2)" "unprognostic (3.31e-3)" "unprognostic (3.86e-1)" "unprognostic (2.02e-2)" "unprognostic (1.43e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.06e-2)" 1.3 1.8 2.0 0.6 1.8 0.0 2.7 64.4 3.8 1.5 0.6 0.8 0.2 0.4 0.1 0.8 2.8 0.7 1.7 3.3 6.4 0.4 13.4 0.5 0.4 2.6 4.2 0.4 0.1 0.0 0.5 0.0 6.3 0.6 0.9 2.9 0.8 0.9 0.2 0.6 0.9 0.7 3.9 0.3 0.5 0.7 0.5 0.0 1.7 1.1 0.2 0.7 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 4.3 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 1.9 0.0 0.0 0.0 11.1 13.7 0.0 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.8 64.4 3.8 3.3 6.4 2.6 4.2 6.3 3.9 0.5 0.5 1.0 0.0 0.0 9.1 0.5 0.6 0.0 0.0 0.6 30.2 0.5 0.4 5.1 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 13.6 0.1 0.0 8.3 0.0 7.0 2.6 1.2 0.1 7.5 0.0 0.1 0.0 0.0 128.5 3.3 0.2 0.0 372.4 0.0 0.0 5.3 2.2 6.1 0.0 0.1 0.0 2.8 0.0 0.2 0.0 3.0 10.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.8 0.7 0.1 0.8 0.0 0.6 0.3 0.4 0.0 0.0 0.0 RELT "FLJ14993, TNFRSF19L" ENSG00000054967 "RELT TNF receptor" Q969Z4 11 73376399-73397474 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Receptor "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 154.7" "Cell type enhanced" "Detected in many" "Langerhans cells: 43.9;Macrophages: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062824, HPA071518" Supported Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA062824: AB_2684875, HPA071518: AB_2686408" "unprognostic (3.49e-1)" "unprognostic (2.43e-1)" "unprognostic (2.25e-1)" "unprognostic (1.67e-2)" "unprognostic (1.80e-3)" "unprognostic (9.92e-3)" "unprognostic (1.67e-3)" "unprognostic (1.17e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-1)" "unprognostic (8.42e-2)" "unprognostic (4.13e-2)" "prognostic unfavorable (4.07e-11)" "unprognostic (1.64e-1)" "unprognostic (3.07e-3)" "unprognostic (2.01e-2)" "unprognostic (1.69e-1)" 4.9 2.2 3.4 12.9 6.5 154.7 2.5 6.7 7.7 1.4 0.4 2.3 2.3 1.4 0.5 3.9 1.9 4.5 6.2 3.6 7.0 3.7 2.1 10.9 11.9 8.9 6.8 1.8 0.8 1.1 3.5 4.6 8.1 2.1 1.4 2.2 1.9 0.4 24.3 3.2 7.1 2.6 7.0 20.8 2.2 3.2 6.9 4.6 2.2 6.4 6.9 4.8 2.3 12.6 9.1 8.9 7.0 6.8 0.8 1.0 7.5 9.6 6.2 11.1 6.7 8.5 3.9 16.4 30.9 6.4 8.8 13.1 4.4 4.7 4.3 9.9 8.3 15.4 12.4 3.1 1.8 15.6 26.3 1.1 2.0 11.9 3.5 2.6 4.1 8.4 11.8 21.0 3.1 8.5 11.5 16.5 6.1 6.9 11.0 21.9 11.7 14.2 2.3 3.9 8.9 8.5 8.3 7.5 10.0 1.7 4.1 13.9 5.4 13.8 9.7 23.1 17.6 7.5 6.1 18.2 8.5 15.5 14.8 0.7 12.5 22.2 0.9 25.4 2.0 7.6 1.0 1.7 11.8 5.8 1.3 0.6 19.9 0.4 35.3 11.7 0.5 6.3 3.4 6.5 6.7 7.7 3.6 7.0 8.9 6.8 8.1 7.0 6.9 12.6 5.7 6.4 2.2 3.6 24.2 26.5 15.4 2.8 2.8 3.5 6.1 5.5 2.7 1.5 3.4 0.0 12.5 1.6 33.0 4.7 0.0 3.6 0.9 5.4 5.2 7.2 3.5 5.7 3.1 0.9 10.7 10.1 11.2 10.8 24.8 6.8 1.8 0.2 23.0 30.3 4.5 2.8 6.1 24.2 43.9 1.2 0.0 43.9 5.4 2.8 32.8 8.9 3.1 1.5 4.8 6.7 2.4 0.0 19.2 9.9 1.0 0.5 1.4 2.8 6.6 7.2 14.5 11.7 10.5 4.6 18.3 21.1 16.1 0.6 3.1 17.8 REN ENSG00000143839 Renin P00797 1 204154819-204190324 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "kidney: 162.2" "Cell type enhanced" "Detected in some" "Early spermatids: 6.8;Late spermatids: 28.4;Paneth cells: 5.6;Smooth muscle cells: 10.7;Urothelial cells: 7.0" "Cancer enriched" "Detected in many" 8 "renal cancer: 39.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.0;BJ: 2.0;HMC-1: 2.6;SK-BR-3: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA005131 Approved "Secreted to blood" NA NA 692000 10000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 33: Fibroblasts - ECM organization" "HPA005131: AB_1079174" "unprognostic (4.45e-2)" "unprognostic (3.35e-1)" "unprognostic (1.62e-1)" "unprognostic (8.58e-2)" "unprognostic (2.89e-1)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (6.49e-2)" 1.0 1.4 0.3 0.2 0.9 0.0 0.1 0.0 0.2 4.3 3.2 0.4 0.3 9.6 0.3 0.2 2.3 0.1 1.8 0.2 0.0 162.2 0.7 0.7 0.0 0.3 0.4 16.3 0.0 0.0 0.6 15.2 0.1 0.3 0.2 0.1 0.8 0.8 0.0 0.1 0.1 1.5 0.0 0.1 0.0 0.9 0.2 0.5 0.0 0.0 0.5 5.2 0.3 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.2 0.2 0.0 0.3 0.4 0.1 0.0 0.2 0.0 0.0 0.0 1.5 1.0 0.0 0.0 0.8 0.7 0.0 0.7 0.1 0.0 0.2 0.0 0.3 1.8 0.0 0.3 0.0 0.0 0.0 1.2 6.8 0.2 0.5 0.4 0.0 0.0 0.3 1.1 0.2 2.8 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 28.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 5.6 0.4 0.0 1.8 0.0 0.0 0.0 0.3 0.0 0.0 10.7 0.3 0.2 0.0 0.0 1.1 0.1 1.3 0.0 7.0 REPIN1 "AP4, H_DJ0584D14.12, RIP60, Zfp464, ZNF464" ENSG00000214022 "Replication initiator 1" Q9BWE0 7 150368189-150374044 "Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 7.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 246.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036022 Approved Supported Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA036022: AB_10610417" "unprognostic (2.73e-1)" "unprognostic (2.21e-2)" "unprognostic (1.54e-1)" "unprognostic (7.50e-3)" "unprognostic (5.42e-2)" "unprognostic (7.00e-3)" "unprognostic (1.52e-2)" "unprognostic (6.88e-3)" "unprognostic (6.68e-2)" "unprognostic (6.59e-2)" "prognostic favorable (1.12e-4)" "unprognostic (3.40e-2)" "prognostic favorable (5.56e-4)" "prognostic favorable (1.61e-4)" "unprognostic (1.79e-1)" "unprognostic (2.02e-3)" "prognostic favorable (6.41e-4)" 28.7 77.2 45.1 25.2 43.6 44.1 35.1 43.1 46.4 31.7 54.6 68.4 42.2 37.5 31.8 37.4 40.9 14.6 65.3 37.9 40.0 51.5 86.6 31.7 35.7 52.3 46.7 37.3 67.7 35.5 69.7 12.1 45.5 49.2 28.3 23.7 41.7 23.9 134.5 31.8 56.5 15.4 41.1 56.2 53.1 18.2 49.5 41.0 45.0 66.2 24.8 42.5 25.0 42.1 59.4 71.3 66.1 81.5 15.8 11.3 40.2 28.7 35.2 27.6 23.8 55.5 37.6 65.5 70.9 20.6 48.0 43.4 36.4 11.4 13.9 72.0 54.8 38.4 40.3 70.4 52.3 68.4 60.1 14.7 34.1 15.2 3.5 26.1 39.4 39.1 93.5 39.9 23.1 76.7 95.1 77.4 69.5 39.7 69.9 51.8 76.4 246.3 29.4 103.7 96.9 123.7 43.3 107.5 75.8 27.2 52.8 54.2 42.1 21.2 17.4 23.6 58.7 115.4 46.1 59.8 37.1 59.9 53.3 0.0 1.4 2.7 0.8 0.7 1.3 2.5 1.8 1.5 2.2 2.4 2.3 1.1 1.4 1.8 0.3 7.8 0.8 0.9 45.1 43.6 43.1 46.4 37.9 40.0 52.3 46.7 45.5 41.1 49.5 42.1 21.1 35.3 18.6 17.9 26.9 9.4 18.3 11.5 14.8 57.9 39.3 33.1 46.5 45.8 15.0 14.7 41.7 28.0 49.5 53.7 62.6 37.3 7.8 53.4 14.3 24.3 68.1 14.5 13.0 50.3 12.9 16.1 23.4 35.8 24.7 56.3 26.0 69.7 32.0 80.8 15.8 68.6 32.6 14.8 23.9 9.8 22.1 21.8 16.0 9.4 88.4 101.3 40.2 17.6 16.6 34.3 37.1 19.9 26.4 31.6 47.0 32.8 36.2 55.8 6.6 28.0 20.1 10.2 3.1 17.6 17.8 25.6 16.0 33.5 109.7 19.9 REPS2 POB1 ENSG00000169891 "RALBP1 associated Eps domain containing 2" Q8NFH8 X 16946658-17153272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 117.9;Inhibitory neurons: 142.7;Oligodendrocyte precursor cells: 84.9;Oligodendrocytes: 204.0" "Cancer enhanced" "Detected in all" "prostate cancer: 13.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "basophil: 5.8;eosinophil: 4.5;neutrophil: 14.3" "Lineage enriched" "Detected in single" 28 "granulocytes: 14.3" "Cell line enhanced" "Detected in some" "HDLM-2: 30.2;Karpas-707: 11.7;RH-30: 8.4;RPMI-8226: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000565, HPA026073" Uncertain "Intracellular and membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 68: Epididymis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA000565: AB_1079800, HPA026073: AB_1856176" "unprognostic (6.58e-2)" "unprognostic (2.14e-1)" "unprognostic (3.35e-2)" "unprognostic (7.83e-2)" "unprognostic (4.23e-2)" "unprognostic (3.70e-3)" "prognostic favorable (5.36e-4)" "unprognostic (4.85e-2)" "unprognostic (2.87e-2)" "unprognostic (5.53e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (1.83e-1)" "prognostic favorable (4.08e-4)" "unprognostic (5.89e-2)" "unprognostic (1.03e-1)" "unprognostic (2.43e-2)" "prognostic favorable (4.56e-4)" 2.4 11.1 7.6 1.2 9.4 3.0 3.3 2.4 29.1 15.9 1.6 4.3 2.1 4.2 12.6 1.3 2.1 2.1 1.6 11.2 9.2 11.0 7.6 4.6 0.5 2.4 4.4 4.0 10.3 9.4 6.0 2.6 3.4 8.2 4.6 9.3 5.1 7.8 0.9 0.9 2.0 4.2 0.9 1.2 6.3 2.1 9.3 0.7 2.0 1.3 0.6 1.8 0.9 12.5 1.4 0.6 0.0 0.1 0.8 0.5 0.1 0.0 0.0 0.1 0.2 0.1 5.2 0.0 0.6 0.0 3.9 0.2 1.1 2.8 0.5 30.2 0.6 0.0 0.7 0.0 0.7 0.0 0.1 5.3 0.9 0.0 4.7 4.9 1.6 0.0 0.0 11.7 0.3 1.4 0.0 0.4 0.2 4.3 0.9 0.0 8.4 9.4 0.3 2.8 4.2 0.3 2.2 2.1 1.7 1.7 3.9 0.2 0.2 0.0 0.2 0.1 0.4 0.5 0.0 0.4 0.0 0.4 0.2 5.8 0.3 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 14.3 0.0 0.2 0.3 0.0 0.1 7.6 9.4 2.4 29.1 11.2 9.2 2.4 4.4 3.4 0.9 9.3 12.5 11.7 32.1 13.5 6.5 0.9 0.6 9.6 4.4 1.2 49.5 7.9 5.5 6.6 4.3 8.8 14.7 0.0 0.2 1.5 10.4 1.9 3.0 0.2 7.1 4.0 2.3 9.5 4.4 117.9 14.6 9.1 4.1 9.7 9.6 0.0 7.9 4.2 15.1 4.2 38.7 142.7 7.8 0.0 5.7 6.4 0.9 9.3 6.6 1.8 21.5 4.9 0.9 0.0 84.9 204.0 7.9 5.1 12.8 1.3 10.6 2.3 11.6 2.7 2.6 0.0 0.8 2.0 0.7 2.6 0.9 1.3 0.7 0.5 16.3 10.2 6.5 RESP18 ENSG00000182698 "Regulated endocrine specific protein 18" Q5W5W9 2 219327407-219333177 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "brain: 14.8" "Group enriched" "Detected in some" 6 "Early spermatids: 9.4;Late spermatids: 32.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 65: Brain - Ion transport" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.57e-2)" "unprognostic (2.12e-1)" 0.0 0.0 2.9 0.0 14.8 0.0 0.0 1.5 7.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 5.4 0.0 0.0 0.0 0.0 3.8 5.2 0.0 0.0 0.0 0.2 0.0 4.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.4 5.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 14.8 1.5 7.4 5.0 5.4 3.8 5.2 4.1 1.9 5.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8" "Group enriched" "Detected in some" 4 "Horizontal cells: 79.1;Ionocytes: 26.4;Skeletal myocytes: 23.1" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 74.6;NB-4: 42.2;SH-SY5Y: 329.3;THP-1: 95.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 53.3;spinal cord: 19.4" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 20.8 1.0 1.3 0.9 0.4 1.1 5.1 5.6 1.0 0.2 3.4 1.4 0.6 0.3 0.4 0.5 0.6 2.2 0.3 5.5 0.9 3.0 0.4 0.6 14.4 27.3 0.4 1.3 31.8 5.3 0.5 12.0 1.8 1.4 4.7 5.1 2.0 5.9 0.9 1.4 1.0 4.8 0.2 2.2 2.7 7.6 1.6 0.8 3.1 0.2 0.6 1.4 5.8 0.1 0.4 0.1 1.7 0.0 0.0 0.1 0.7 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 42.2 7.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.7 329.3 0.1 0.0 0.1 0.5 4.1 95.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.1 0.0 1.0 0.9 5.1 5.6 0.3 5.5 14.4 27.3 12.0 4.8 7.6 5.8 0.4 0.0 0.5 1.6 0.0 0.3 0.8 0.0 0.0 1.7 6.0 0.5 2.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 1.5 0.0 0.3 1.1 0.0 0.0 4.2 0.2 2.3 6.8 0.0 0.0 1.3 0.5 0.0 1.2 0.1 79.1 8.6 1.9 26.4 0.0 0.6 1.5 0.3 0.5 0.0 1.0 0.0 0.8 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.8 1.7 0.0 23.1 1.2 1.1 4.7 0.0 0.6 0.0 0.2 0.3 0.2 0.1 RETN "ADSF, FIZZ3, RETN1" ENSG00000104918 Resistin Q9HD89 19 7669049-7670455 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Hormone "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 247.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 118.2;Kupffer cells: 47.0;Macrophages: 90.4;monocytes: 58.2" "Group enriched" "Detected in many" 4 "lung cancer: 2.6;pancreatic cancer: 4.8;thyroid cancer: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "classical monocyte: 170.4;intermediate monocyte: 91.7;myeloid DC: 118.7;non-classical monocyte: 47.4" "Group enriched" "Detected in many" 11 "dendritic cells: 118.7;monocytes: 170.4" "Group enriched" "Detected in some" 11 "NB-4: 524.3;U-937: 243.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 5120000 1200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.61e-2)" "unprognostic (6.20e-3)" "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (5.19e-4)" "unprognostic (1.53e-4)" "unprognostic (7.34e-2)" "unprognostic (3.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (4.02e-1)" "unprognostic (7.16e-5)" "unprognostic (4.23e-2)" "unprognostic (2.26e-1)" "unprognostic (8.91e-2)" "unprognostic (1.20e-1)" 3.4 1.0 0.1 5.2 0.1 247.2 1.4 0.0 0.9 0.6 0.0 0.8 6.1 0.7 0.0 0.5 2.4 0.3 2.3 0.4 0.1 1.7 3.3 34.0 0.1 0.1 0.1 0.4 0.9 0.1 0.5 1.1 0.1 1.0 0.2 0.0 1.1 0.0 0.6 0.7 0.7 4.3 0.0 53.3 1.0 0.2 0.0 4.0 0.8 0.0 0.0 0.6 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.7 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.9 524.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 243.2 0.0 0.1 170.4 0.1 0.4 91.7 1.2 0.0 1.9 1.5 118.7 0.1 4.4 9.0 13.6 0.3 47.4 4.5 0.0 64.3 0.1 0.1 0.0 0.9 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 12.8 9.9 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 1.1 0.6 0.0 0.0 3.8 0.0 0.4 0.1 118.2 0.0 0.0 0.0 0.0 47.0 8.7 0.2 0.0 90.4 0.0 0.0 58.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 2.2 0.0 0.0 0.1 RETNLB "FIZZ2, HXCP2, RELMb" ENSG00000163515 "Resistin like beta" Q9BQ08 3 108743424-108757384 "Predicted secreted proteins, Transporters" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "intestine: 245.5" "Cell type enriched" "Detected in some" 38 "Intestinal goblet cells: 210.1" "Cancer enriched" "Detected in some" 10 "colorectal cancer: 16.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "OE19: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA049152 Enhanced "Secreted to blood" NA NA 123000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA049152: AB_2680655" "prognostic favorable (6.86e-5)" "unprognostic (1.19e-3)" "unprognostic (3.37e-2)" "unprognostic (4.69e-2)" "unprognostic (2.67e-2)" "unprognostic (5.78e-2)" "unprognostic (4.26e-1)" 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 75.7 16.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 245.5 0.0 0.0 0.1 0.0 0.0 34.5 0.8 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 2.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 210.1 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 5.5 0.0 RETSAT FLJ20296 ENSG00000042445 "Retinol saturase" Q6NUM9 2 85341955-85354531 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 247.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 264.9;Proximal enterocytes: 249.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 197.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007961, HPA046513" Uncertain Uncertain Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Nucleoli "HPA007961: AB_1079802, HPA046513: AB_2679680" "unprognostic (6.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.29e-1)" "unprognostic (5.84e-3)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "prognostic favorable (4.23e-4)" "unprognostic (1.89e-1)" "unprognostic (2.16e-1)" "unprognostic (3.59e-2)" "unprognostic (1.77e-2)" "unprognostic (1.59e-1)" "prognostic favorable (1.95e-10)" "unprognostic (2.73e-2)" "unprognostic (5.34e-1)" "unprognostic (8.24e-3)" "unprognostic (9.90e-2)" 247.0 52.3 16.5 17.6 20.9 3.8 63.9 19.8 15.8 18.9 27.3 89.6 167.0 16.0 38.4 36.9 15.7 32.0 20.3 14.9 20.0 54.9 115.9 24.6 11.7 21.0 20.0 17.0 37.5 36.9 7.2 11.6 20.0 32.5 73.5 9.5 27.8 23.6 68.3 48.8 142.4 22.0 19.2 11.7 60.9 14.6 19.9 12.2 47.4 55.1 19.9 19.0 23.7 23.7 52.7 30.1 16.8 40.0 197.8 37.0 22.1 37.8 46.5 22.5 31.5 20.9 36.2 18.5 30.3 29.6 17.9 42.6 22.9 65.6 21.6 22.8 15.9 9.0 23.5 50.6 47.6 17.9 19.3 48.6 87.2 28.7 38.1 51.4 37.6 15.4 9.7 43.1 42.0 11.0 12.5 9.0 5.6 52.6 36.2 8.1 33.7 23.9 39.1 30.1 8.3 13.8 31.4 59.9 101.8 11.2 28.2 2.9 30.0 25.3 13.8 23.5 19.9 23.0 22.9 7.2 30.9 20.5 17.6 0.0 3.8 1.8 4.8 4.0 6.2 2.6 3.5 6.0 4.0 1.5 2.5 2.5 3.7 5.1 8.7 2.7 4.2 3.4 16.5 20.9 19.8 15.8 14.9 20.0 21.0 20.0 20.0 19.2 19.9 23.7 7.3 28.9 29.6 5.9 4.5 11.3 10.8 18.6 12.5 3.7 13.0 7.9 21.7 21.5 15.5 12.9 18.8 10.9 4.3 264.9 0.0 23.7 27.6 9.7 6.8 9.7 10.8 2.5 5.7 36.1 6.5 9.0 56.1 16.6 10.8 5.5 7.5 54.7 9.9 11.8 4.5 45.0 8.2 10.4 8.6 60.0 14.6 7.4 30.2 7.5 8.3 8.3 10.3 6.6 12.1 32.7 79.2 12.4 10.3 11.8 249.9 17.8 11.9 4.9 0.0 7.7 8.8 2.9 3.1 24.9 14.9 8.5 7.7 9.9 56.6 9.8 RFNG ENSG00000169733 "RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q9Y644 17 82047902-82051831 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HHSteC: 69.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011564, HPA031673" Uncertain Approved Nucleoplasm No No 1100000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA011564: AB_1079803, HPA031673: AB_2673989" "unprognostic (4.17e-3)" "unprognostic (7.60e-3)" "unprognostic (2.87e-3)" "unprognostic (2.49e-1)" "unprognostic (2.05e-1)" "unprognostic (2.65e-2)" "unprognostic (1.62e-1)" "unprognostic (9.86e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "prognostic favorable (4.81e-4)" "unprognostic (1.20e-1)" "unprognostic (6.96e-3)" "unprognostic (1.77e-1)" "unprognostic (2.16e-1)" "unprognostic (6.93e-2)" "unprognostic (4.14e-2)" 28.3 24.3 9.9 3.8 9.7 10.2 24.6 8.5 11.8 25.5 7.8 26.5 11.1 25.3 1.6 24.1 23.0 10.9 19.5 8.7 9.0 22.9 78.5 18.7 5.4 10.4 9.3 29.7 42.6 11.1 20.0 5.9 9.5 23.5 3.2 1.4 22.0 6.9 45.4 27.1 16.7 7.7 9.0 14.9 27.7 23.2 9.6 4.6 19.8 10.5 2.7 24.0 18.6 9.7 20.3 19.2 5.6 19.1 13.9 11.8 24.4 18.5 10.1 8.2 6.2 11.6 13.7 4.5 13.0 29.1 17.4 10.8 3.9 15.8 1.5 6.0 19.7 6.7 4.4 48.5 69.3 2.4 14.2 22.5 9.9 14.7 24.9 16.5 15.8 15.2 8.5 16.9 6.6 24.1 15.1 6.5 5.5 13.5 20.1 10.2 7.0 10.6 9.5 11.8 9.7 24.9 7.1 10.7 54.7 6.2 32.1 13.7 6.1 13.1 17.9 12.7 10.2 22.9 4.5 5.0 16.8 4.4 11.7 1.0 1.9 2.0 1.7 0.5 0.6 1.0 1.1 1.6 1.4 1.2 1.1 0.6 0.7 0.2 0.7 1.1 2.5 0.6 9.9 9.7 8.5 11.8 8.7 9.0 10.4 9.3 9.5 9.0 9.6 9.7 24.3 6.4 12.4 30.7 7.6 9.7 11.9 8.3 6.8 26.9 33.3 35.4 12.8 18.6 5.6 23.9 25.0 5.5 14.2 20.9 7.9 7.8 3.7 14.9 24.4 12.1 11.4 5.7 20.7 15.1 3.3 27.2 18.8 19.0 1.3 52.5 21.8 47.1 9.6 11.8 20.3 14.0 12.2 15.2 6.3 13.3 21.8 14.7 10.6 16.9 6.2 29.8 3.1 20.6 13.5 12.4 16.3 19.9 4.9 15.9 14.0 31.3 6.8 27.8 0.0 28.0 19.4 14.4 6.2 9.0 10.2 3.7 10.4 32.8 13.5 8.7 RFXAP ENSG00000133111 "Regulatory factor X associated protein" O00287 13 36819222-36829104 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding SCID "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032035 Approved "Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA032035: AB_2674120" "unprognostic (2.03e-1)" "unprognostic (9.69e-2)" "unprognostic (7.40e-2)" "unprognostic (3.13e-1)" "unprognostic (5.14e-3)" "unprognostic (4.45e-3)" "unprognostic (1.15e-2)" "prognostic favorable (2.26e-5)" "unprognostic (1.45e-1)" "unprognostic (2.94e-1)" "prognostic favorable (4.18e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "prognostic favorable (4.91e-4)" "unprognostic (2.81e-2)" "unprognostic (4.09e-1)" "unprognostic (5.99e-3)" 4.3 3.4 3.8 5.0 4.2 6.0 4.7 6.8 5.2 6.3 2.5 5.1 3.1 6.8 5.1 3.0 5.8 4.1 3.5 3.9 3.5 3.3 2.6 4.3 6.7 3.3 3.7 7.0 4.6 6.2 4.6 3.7 3.5 5.2 4.1 5.5 4.8 3.8 4.3 3.5 4.4 5.8 4.0 5.1 4.2 6.5 3.4 8.3 5.8 3.0 5.4 4.0 3.8 4.3 7.4 1.8 10.4 14.7 3.8 5.2 6.7 5.9 6.2 10.9 6.7 5.2 5.9 32.3 4.8 5.4 9.6 6.7 10.8 3.6 12.2 24.4 17.9 15.5 8.6 10.2 6.9 28.7 10.9 4.8 6.3 5.3 4.0 3.1 8.3 24.4 9.0 6.4 3.3 3.6 28.8 20.5 11.1 6.4 3.2 24.9 19.3 9.8 4.6 4.5 8.5 10.6 5.7 3.8 4.7 6.3 3.9 16.9 6.5 2.8 6.1 9.8 5.5 6.0 5.3 24.2 7.9 19.6 4.5 0.0 0.0 0.5 0.2 0.0 0.1 0.3 0.1 0.2 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.3 0.2 0.0 3.8 4.2 6.8 5.2 3.9 3.5 3.3 3.7 3.5 4.0 3.4 4.3 6.6 3.2 3.9 11.1 10.4 3.6 3.3 2.5 7.4 14.5 4.9 4.4 3.6 1.5 2.7 3.7 2.1 6.4 11.1 2.0 15.6 4.2 5.3 4.3 7.5 7.0 7.2 16.0 26.4 5.5 2.8 9.8 4.6 3.0 10.2 10.9 7.9 2.2 3.1 23.5 27.5 2.8 2.0 1.9 7.4 4.1 11.1 4.1 7.2 7.5 5.5 20.8 17.5 11.1 23.9 2.8 2.5 10.9 6.4 1.5 3.3 1.4 2.2 18.0 6.6 13.1 10.0 20.1 25.8 2.8 2.0 1.2 11.7 8.2 3.6 0.8 RGCC "bA157L14.2, C13orf15, RGC-32, RGC32" ENSG00000102760 "Regulator of cell cycle" Q9H4X1 13 41457550-41470871 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 415.4;lung: 694.9" "Cell type enhanced" "Detected in many" "Adipocytes: 1286.2;Basal prostatic cells: 676.2;Langerhans cells: 590.1;Prostatic glandular cells: 1415.5;T-cells: 532.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 159.9;T-reg: 90.9" "Lineage enriched" "Detected in many" 15 "T-cells: 159.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 57.5;BJ hTERT+: 316.0;Daudi: 105.1;U-698: 111.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035638, HPA063701" Enhanced Supported Nucleoplasm,Nucleoli "Intracellular and membrane" No No 910000 "Cluster 20: T-cells - T-cell receptor" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Nucleoli "HPA035638: AB_10670152, HPA063701: AB_2685096" "unprognostic (1.39e-3)" "unprognostic (4.61e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (2.28e-1)" "unprognostic (4.27e-2)" "unprognostic (2.85e-1)" "unprognostic (1.49e-3)" "unprognostic (1.49e-2)" "unprognostic (3.99e-2)" "unprognostic (1.57e-3)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.81e-2)" "unprognostic (3.04e-3)" "unprognostic (1.48e-1)" "unprognostic (2.30e-1)" "unprognostic (1.42e-3)" 197.6 21.5 186.3 27.7 226.9 415.4 132.6 218.8 236.7 36.1 148.2 34.7 16.9 43.6 7.6 18.6 31.1 42.2 145.9 195.8 196.6 56.9 25.0 694.9 38.1 209.1 204.8 9.1 41.3 48.1 35.3 150.7 205.3 61.5 9.2 5.7 111.5 19.0 47.3 58.0 29.1 33.5 186.7 37.0 37.8 24.8 198.2 70.5 144.0 61.8 21.0 47.5 39.6 241.0 1.1 0.5 34.9 0.0 6.7 57.5 1.4 0.8 316.0 0.2 1.2 44.8 0.7 105.1 0.9 4.0 0.1 1.0 1.2 2.1 0.4 11.1 5.1 0.0 7.9 3.5 3.3 3.7 1.2 4.5 6.7 1.2 43.1 0.6 36.1 24.0 8.3 0.1 1.0 0.3 24.0 2.3 0.5 4.7 0.8 0.1 0.0 0.1 0.3 0.0 1.3 0.4 0.3 0.0 0.7 3.0 0.9 20.1 24.6 0.2 3.8 2.2 0.4 0.2 0.1 111.9 0.3 2.4 0.8 0.0 0.8 0.1 5.6 0.5 5.6 5.3 46.5 14.7 6.1 10.7 159.9 35.0 0.6 0.4 0.1 1.8 90.9 10.2 186.3 226.9 218.8 236.7 195.8 196.6 209.1 204.8 205.3 186.7 198.2 241.0 1286.2 246.8 39.8 57.5 131.8 86.5 676.2 15.2 14.2 1.0 269.9 314.7 25.8 1.5 37.5 3.7 2.1 6.4 249.2 3.0 35.2 0.6 42.3 103.0 47.2 474.6 84.8 322.7 2.5 0.0 9.3 205.1 65.2 69.0 48.9 0.3 31.8 2.5 349.1 0.0 1.2 22.1 14.2 32.0 590.1 13.2 8.1 315.9 193.9 36.5 6.4 1.5 4.1 51.8 115.3 0.3 4.5 2.2 371.2 1415.5 0.1 0.8 33.7 3.1 124.9 45.4 116.0 155.3 5.0 11.2 65.1 11.1 532.4 43.8 7.8 159.7 RGL4 Rgr ENSG00000159496 "Ral guanine nucleotide dissociation stimulator like 4" Q8IZJ4 22 23688136-23699176 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "bone marrow: 164.4" "Group enriched" "Detected in some" 4 "dendritic cells: 23.8;Early spermatids: 18.1;NK-cells: 52.5;T-cells: 51.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 393.6;neutrophil: 516.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 516.3" "Group enriched" "Detected in many" 5 "MOLT-4: 26.3;U-937: 61.0" HPA035979 Uncertain Approved Centrosome "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA035979: AB_10673227" "unprognostic (1.48e-4)" "unprognostic (2.75e-4)" "unprognostic (4.44e-2)" "unprognostic (1.11e-4)" "unprognostic (3.10e-1)" "unprognostic (2.93e-4)" "unprognostic (4.92e-2)" "unprognostic (2.06e-2)" "unprognostic (2.78e-1)" "unprognostic (3.11e-1)" "unprognostic (4.25e-2)" "unprognostic (3.80e-2)" "unprognostic (2.37e-1)" "unprognostic (1.66e-1)" "unprognostic (5.13e-2)" "unprognostic (1.26e-1)" "unprognostic (1.07e-3)" 3.8 3.1 0.1 7.6 0.2 164.4 0.5 2.0 0.8 0.3 0.3 1.2 4.1 3.1 0.0 1.9 0.9 4.6 2.8 0.2 0.0 1.5 1.3 4.8 11.5 0.6 0.1 3.9 3.4 0.1 0.5 1.7 1.0 1.4 1.1 10.6 4.6 0.2 3.0 5.6 4.1 0.6 0.1 19.8 2.4 3.8 0.1 8.4 3.1 0.9 8.1 3.8 0.5 1.1 1.6 0.5 5.8 2.5 0.0 0.0 2.5 1.8 0.0 0.0 0.0 1.3 1.1 1.9 0.4 0.0 1.0 2.8 0.0 0.0 0.0 2.0 3.6 0.9 2.5 0.3 0.0 3.4 3.8 0.0 0.0 0.0 0.0 2.9 0.0 2.0 2.1 3.0 0.0 1.0 26.3 3.6 0.4 0.6 0.8 9.3 2.0 1.4 0.0 1.7 1.8 2.7 1.7 3.7 0.6 3.1 1.2 2.0 2.5 3.2 1.9 2.2 1.1 5.3 0.8 1.3 1.9 61.0 1.6 98.0 2.9 393.6 57.4 20.8 59.6 6.5 74.1 66.2 5.4 5.2 104.6 93.8 516.3 35.2 84.6 0.7 114.2 37.4 0.1 0.2 2.0 0.8 0.2 0.0 0.6 0.1 1.0 0.1 0.1 1.1 0.7 0.0 4.4 0.3 5.9 0.9 0.0 0.0 0.0 0.5 0.4 0.5 0.5 1.5 1.3 0.0 2.1 0.0 23.8 0.0 0.0 2.4 18.1 0.1 0.3 0.3 0.0 8.8 0.4 1.7 0.1 0.6 2.6 0.2 1.3 0.1 0.4 0.3 0.1 1.7 0.5 0.0 0.0 1.6 0.7 2.0 0.0 3.5 1.8 0.0 2.5 0.0 52.5 0.5 0.4 2.2 0.0 0.0 3.4 0.0 0.0 0.3 0.0 2.8 0.0 0.3 0.5 5.9 0.0 0.0 0.3 0.0 51.8 0.1 0.1 0.1 RGMA RGM ENSG00000182175 "Repulsive guidance molecule BMP co-receptor a" Q96B86 15 93035273-93089204 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.3;skeletal muscle: 199.1" "Cell type enhanced" "Detected in many" "Astrocytes: 143.3;Leydig cells: 119.0;Peritubular cells: 116.9;Prostatic glandular cells: 61.3;Skeletal myocytes: 69.3;Squamous epithelial cells: 58.3" "Cancer enriched" "Detected in many" 6 "glioma: 26.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 50.0;BEWO: 14.6;MOLT-4: 15.5;NTERA-2: 22.2;REH: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012343, HPA039880, HPA044222" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 2000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "CAB012343: AB_777667, HPA039880: AB_2676723, HPA044222: AB_2678861" "unprognostic (3.21e-2)" "unprognostic (1.59e-1)" "unprognostic (8.85e-2)" "unprognostic (3.96e-3)" "unprognostic (5.73e-2)" "unprognostic (4.72e-3)" "unprognostic (2.53e-2)" "prognostic favorable (2.78e-4)" "unprognostic (2.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (6.25e-2)" "unprognostic (3.59e-4)" "unprognostic (8.11e-2)" "unprognostic (2.92e-2)" "unprognostic (1.73e-1)" "unprognostic (7.98e-5)" 30.2 3.2 62.1 22.5 73.8 0.4 30.3 72.5 59.1 55.9 7.7 79.4 9.9 50.9 2.9 57.4 39.9 7.7 29.4 60.4 68.0 3.6 0.6 4.6 2.4 126.3 113.9 38.5 11.4 0.8 6.9 1.3 70.4 12.8 6.2 1.0 24.2 6.4 199.1 17.1 42.9 60.6 91.5 1.3 73.6 33.5 120.6 2.6 10.0 45.0 3.4 10.0 29.2 62.8 2.1 0.3 50.0 0.8 10.3 5.7 14.6 0.3 0.0 0.0 0.0 0.6 0.6 0.1 0.2 0.4 0.0 3.4 8.4 0.2 0.0 0.0 9.2 0.1 0.3 0.0 0.0 0.1 0.2 6.1 0.2 0.0 0.0 0.3 0.0 0.9 0.0 0.1 0.0 1.0 15.5 0.2 22.2 0.1 0.0 13.1 11.4 0.1 0.0 0.5 5.1 3.0 0.5 0.2 0.0 2.6 4.0 2.7 0.0 0.1 10.4 0.3 0.1 0.1 0.0 0.2 0.2 0.2 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 62.1 73.8 72.5 59.1 60.4 68.0 126.3 113.9 70.4 91.5 120.6 62.8 4.2 0.0 1.5 143.3 0.5 5.5 20.4 10.2 40.5 1.9 7.5 4.4 4.4 0.0 3.9 0.0 2.1 4.4 0.5 0.3 0.0 6.5 1.2 0.6 10.9 2.7 0.0 0.4 16.8 0.7 1.2 40.5 1.5 2.3 0.0 0.6 1.8 0.3 2.1 0.0 2.8 0.0 12.2 2.5 2.3 6.4 119.0 1.6 3.6 9.4 0.6 4.5 0.0 11.1 1.6 0.4 0.0 116.9 0.1 61.3 0.0 0.1 1.3 1.2 13.1 69.3 20.3 0.9 43.8 58.3 2.8 2.5 1.4 0.1 0.1 29.2 RGMB "DRAGON, FLJ90406" ENSG00000174136 "Repulsive guidance molecule BMP co-receptor b" Q6NW40 5 98768650-98798643 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 63.9;Undifferentiated cells: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 3.3" "Group enriched" "Detected in many" 12 "B-cells: 1.6;T-cells: 3.3" "Cell line enhanced" "Detected in many" "BJ: 285.8;BJ hTERT+: 142.9;fHDF/TERT166: 178.0;HBF TERT88: 222.5;LHCN-M2: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016993 Approved Nucleoplasm NA NA 560000 "Cluster 32: T-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA016993: AB_1856216" "unprognostic (1.50e-2)" "unprognostic (3.77e-2)" "unprognostic (9.03e-2)" "unprognostic (8.92e-2)" "unprognostic (2.88e-1)" "unprognostic (5.27e-2)" "unprognostic (7.44e-2)" "unprognostic (1.60e-2)" "unprognostic (8.24e-2)" "unprognostic (2.19e-1)" "unprognostic (3.60e-3)" "unprognostic (9.00e-2)" "unprognostic (3.88e-2)" "unprognostic (3.90e-2)" "unprognostic (6.40e-2)" "unprognostic (4.20e-2)" "unprognostic (3.78e-3)" 8.8 7.7 14.8 7.2 18.4 0.3 9.1 11.4 17.4 9.3 5.7 20.5 21.4 9.2 6.0 11.8 11.1 7.5 10.2 17.4 15.1 4.7 6.0 8.1 3.7 12.9 16.0 21.8 11.2 9.3 11.4 5.5 27.1 20.7 33.3 3.8 21.8 13.9 24.8 33.8 26.2 10.9 12.2 6.0 41.7 10.5 22.3 2.6 11.5 16.1 4.5 10.8 9.5 14.9 7.3 5.2 87.8 8.1 26.2 44.5 9.1 285.8 142.9 138.5 97.6 4.4 3.5 4.2 10.2 178.0 9.7 7.5 10.4 26.0 222.5 12.5 10.2 0.0 7.1 4.9 12.6 0.9 0.1 37.1 9.4 71.1 28.2 37.6 26.3 13.6 0.0 3.5 167.1 8.1 0.1 0.1 6.0 3.3 14.0 11.4 50.7 7.9 5.4 8.4 35.6 18.0 3.9 9.4 14.1 4.4 7.5 0.4 57.4 86.7 14.2 54.1 133.5 6.0 9.1 5.8 31.9 0.1 19.1 0.0 0.0 0.2 0.1 0.0 0.7 1.1 1.5 0.6 0.0 1.6 3.3 1.5 0.1 0.1 0.0 0.0 2.4 0.8 14.8 18.4 11.4 17.4 17.4 15.1 12.9 16.0 27.1 12.2 22.3 14.9 8.6 16.0 4.1 7.5 12.7 31.0 15.3 6.0 44.3 5.7 17.8 12.4 14.3 7.2 5.3 9.2 16.7 4.5 0.4 12.8 1.9 5.0 63.9 10.2 12.7 10.3 21.8 0.0 20.8 5.3 6.2 19.1 18.8 18.0 0.0 4.0 9.3 8.2 2.1 0.0 23.6 44.6 4.1 1.0 7.2 16.9 9.0 2.4 12.4 5.6 0.7 1.7 0.0 35.2 6.6 8.4 16.3 7.2 1.7 16.1 11.9 1.6 6.1 4.0 0.0 20.3 13.1 7.4 17.5 27.0 24.4 1.8 2.9 5.4 88.9 17.4 RGS3 "C2PA, FLJ20370, PDZ-RGS3" ENSG00000138835 "Regulator of G protein signaling 3" P49796 9 113444731-113597743 "Plasma proteins, Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 111.6;Horizontal cells: 158.2;Proximal tubular cells: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 248.4;HDLM-2: 413.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044234 Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA044234: " "prognostic unfavorable (9.93e-4)" "unprognostic (4.04e-2)" "unprognostic (5.33e-3)" "unprognostic (6.71e-3)" "unprognostic (1.49e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (6.62e-4)" "unprognostic (6.79e-2)" "unprognostic (9.17e-2)" "unprognostic (2.24e-1)" "unprognostic (8.59e-3)" "unprognostic (3.04e-1)" "unprognostic (2.51e-3)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.53e-2)" "unprognostic (2.90e-1)" 60.5 31.5 32.0 18.1 37.3 9.3 43.7 33.7 29.7 17.9 49.7 30.4 16.9 20.8 11.4 10.8 15.2 42.4 95.0 24.0 31.5 70.9 54.5 64.2 23.9 32.2 44.3 10.3 23.9 12.3 16.6 32.3 32.5 26.3 15.8 10.3 10.8 10.2 48.2 15.2 20.0 18.0 28.2 31.9 27.6 31.2 58.0 7.9 24.5 19.2 11.4 26.5 15.4 34.0 4.5 16.6 40.1 37.0 12.2 18.1 2.9 41.2 248.4 32.9 27.9 40.8 14.7 17.9 29.7 33.6 32.8 10.6 0.6 16.0 19.2 413.2 0.1 1.7 13.0 24.8 24.8 0.4 5.5 32.4 16.6 91.4 13.2 72.6 125.4 1.0 0.3 17.1 60.5 18.7 1.2 1.9 10.6 28.6 13.7 1.3 19.8 2.9 67.7 8.1 31.3 4.2 3.9 31.3 24.7 19.6 21.5 3.8 61.2 109.7 11.8 5.1 79.1 8.6 1.5 2.7 126.2 3.8 51.6 10.2 6.8 3.7 24.7 7.1 16.7 2.4 5.7 20.3 6.6 2.4 2.4 10.8 18.5 42.3 6.0 0.3 3.8 15.6 32.0 37.3 33.7 29.7 24.0 31.5 32.2 44.3 32.5 28.2 58.0 34.0 49.5 16.0 13.9 14.4 5.6 12.0 9.9 7.4 4.6 1.4 9.1 10.7 55.8 72.9 8.4 22.0 6.2 4.6 23.5 28.0 82.2 65.1 38.8 9.9 14.9 111.6 0.0 6.1 2.4 30.4 3.7 29.3 27.0 4.0 47.7 12.8 66.0 35.2 15.6 158.2 3.4 7.4 4.1 14.3 13.8 17.4 4.7 14.6 55.2 21.5 10.3 3.5 50.4 3.5 24.4 31.0 23.4 13.9 4.5 5.0 20.5 195.7 7.5 6.4 6.6 8.4 35.4 9.9 1.8 4.1 11.4 3.0 18.4 55.5 11.5 12.9 RHCE "CD240CE, RH" ENSG00000188672 "Rh blood group CcEe antigens" P18577 1 25362249-25430192 "Blood group antigen proteins, CD markers, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "bone marrow: 48.5" "Cell type enriched" "Detected in some" 67 "Erythroid cells: 511.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HEL: 81.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA060951, HPA077385" Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Plasma membrane" "HPA060951: , HPA077385: " "unprognostic (1.37e-1)" "unprognostic (3.53e-1)" "unprognostic (2.38e-1)" "unprognostic (6.75e-2)" "unprognostic (1.41e-2)" "unprognostic (4.91e-2)" "unprognostic (7.01e-2)" "unprognostic (3.12e-2)" "unprognostic (3.81e-2)" "unprognostic (1.35e-1)" "unprognostic (6.08e-2)" "unprognostic (4.61e-2)" "unprognostic (5.77e-5)" "unprognostic (1.38e-1)" "unprognostic (3.94e-2)" "unprognostic (7.15e-3)" "unprognostic (1.63e-1)" 0.3 0.6 1.5 0.1 1.9 48.5 0.3 1.6 3.3 0.3 1.2 0.2 0.2 0.2 4.2 0.6 1.0 0.3 1.2 1.5 1.4 0.4 1.7 0.4 0.5 1.9 1.6 0.5 1.2 0.1 3.4 1.1 1.9 1.0 0.3 2.2 5.5 0.2 1.5 0.6 0.1 0.0 1.5 1.1 0.4 2.2 1.6 0.8 0.6 0.9 0.3 0.1 0.5 2.2 0.2 0.1 0.2 0.5 0.9 0.6 0.1 0.3 0.3 0.4 0.1 0.1 1.5 0.7 1.1 1.0 0.1 0.3 0.0 0.2 0.2 0.4 0.1 81.3 0.0 0.0 1.1 0.0 0.6 1.9 1.5 0.6 0.5 0.0 0.0 0.6 17.5 0.4 0.5 0.8 0.0 0.6 1.7 0.7 0.5 0.2 0.2 2.6 0.0 0.0 0.7 0.8 0.3 0.3 1.0 0.8 0.5 0.0 0.1 0.2 0.0 0.9 0.0 5.1 1.4 1.0 2.9 0.9 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.5 1.9 1.6 3.3 1.5 1.4 1.9 1.6 1.9 1.5 1.6 2.2 0.8 0.0 0.0 5.5 0.8 0.5 0.5 0.3 0.6 4.2 1.1 2.5 0.7 1.5 0.2 0.0 0.0 0.8 1.2 0.5 0.0 0.3 1.1 1.2 0.7 0.4 0.0 511.8 2.9 0.2 0.7 0.4 3.6 0.8 4.5 0.6 0.0 0.7 0.2 6.7 2.3 0.0 0.0 0.6 0.4 0.5 0.6 1.7 0.0 0.0 0.0 4.7 1.0 2.0 2.7 0.5 0.0 0.7 3.0 0.3 0.1 0.0 0.9 2.4 6.6 0.5 0.5 3.0 7.6 0.6 1.4 0.8 0.8 0.7 0.3 0.7 RHOQ "ARHQ, RASL7A, TC10" ENSG00000119729 "Ras homolog family member Q" P17081 2 46541806-46584688 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 189.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.5;classical monocyte: 2.5;eosinophil: 4.2;intermediate monocyte: 2.7;memory B-cell: 1.7;myeloid DC: 1.6;naive B-cell: 2.4;neutrophil: 4.8;non-classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 164.0;ASC TERT1: 132.0;SK-MEL-30: 150.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044938 Approved Vesicles,Cytosol No No "Cluster 24: B-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "HPA044938: AB_2679149" "unprognostic (1.24e-1)" "unprognostic (1.30e-2)" "unprognostic (5.82e-2)" "unprognostic (2.07e-2)" "unprognostic (3.61e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.60e-5)" "unprognostic (2.01e-2)" "unprognostic (9.24e-2)" "unprognostic (2.11e-2)" "unprognostic (1.97e-1)" "unprognostic (5.43e-2)" "unprognostic (3.88e-3)" "unprognostic (1.39e-2)" "unprognostic (1.87e-1)" "unprognostic (7.68e-2)" "unprognostic (3.52e-2)" 96.9 35.7 34.8 30.1 40.1 12.4 64.8 38.9 41.4 59.6 43.9 67.0 11.0 53.2 67.7 18.9 59.3 26.7 196.8 34.3 44.7 44.3 22.6 56.0 23.8 40.9 44.2 40.8 28.6 50.4 29.5 28.6 38.9 50.6 13.5 27.7 32.7 36.5 162.4 28.1 35.3 38.4 39.2 42.7 32.8 10.1 36.8 9.9 39.1 181.3 19.1 62.8 44.7 43.5 12.3 12.4 21.0 28.6 164.0 132.0 3.7 32.8 84.1 16.2 24.4 6.2 4.1 28.7 34.0 58.5 52.4 5.8 20.6 9.8 29.3 10.2 15.3 8.2 9.8 20.9 81.8 8.8 10.7 118.1 17.3 20.1 22.5 39.0 19.3 3.1 12.1 44.0 35.2 8.1 6.9 17.9 20.8 8.9 14.4 5.3 34.5 10.1 23.1 22.4 15.3 50.3 11.6 16.4 150.8 32.9 9.0 20.7 13.2 50.1 44.8 49.3 14.1 48.5 17.7 28.4 73.6 22.1 18.4 1.5 2.5 4.2 0.4 2.7 0.3 1.7 0.2 0.4 1.6 2.4 0.0 0.3 4.8 0.3 1.9 0.6 0.3 0.7 34.8 40.1 38.9 41.4 34.3 44.7 40.9 44.2 38.9 39.2 36.8 43.5 27.9 57.7 22.4 65.3 38.1 22.4 31.0 18.1 11.4 21.1 30.4 22.4 189.2 14.3 22.1 20.2 10.4 14.6 32.2 1.0 17.6 21.4 30.8 22.1 90.2 23.4 6.0 2.1 12.8 32.0 3.6 82.8 4.1 24.6 12.0 12.1 17.5 12.2 44.5 121.1 27.7 5.5 8.2 90.9 77.8 11.4 35.4 90.7 42.7 68.4 55.1 52.9 15.5 52.3 41.5 22.4 0.3 42.5 42.0 41.2 0.2 30.1 18.8 24.2 46.0 54.2 82.3 2.3 4.5 6.8 19.7 25.9 17.0 10.9 1.9 31.9 RIC3 "AYST720, FLJ11608, PRO1385" ENSG00000166405 "RIC3 acetylcholine receptor chaperone" Q7Z5B4 11 8106056-8169055 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 175.2;Cone photoreceptor cells: 143.9;Rod photoreceptor cells: 204.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 12.8;granulocytes: 4.5;T-cells: 6.7" "Cell line enhanced" "Detected in some" "GAMG: 2.3;HMC-1: 2.6;NTERA-2: 5.0;SCLC-21H: 8.3;SH-SY5Y: 5.8;SuSa: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065016 Approved "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 52: Non-specific - Transcription" "HPA065016: AB_2685404" "unprognostic (2.51e-3)" "unprognostic (2.32e-1)" "unprognostic (1.21e-1)" "unprognostic (6.98e-4)" "unprognostic (3.22e-2)" "unprognostic (1.04e-2)" "unprognostic (1.29e-1)" "unprognostic (2.43e-2)" "unprognostic (1.59e-2)" "unprognostic (1.48e-2)" "unprognostic (4.45e-4)" "unprognostic (1.28e-1)" "unprognostic (2.23e-9)" "unprognostic (4.37e-2)" "unprognostic (5.53e-2)" "unprognostic (1.35e-1)" "unprognostic (2.52e-2)" 3.1 13.5 17.9 5.2 17.8 1.9 6.4 24.6 21.7 8.9 14.8 11.3 1.9 10.9 21.5 5.7 10.1 3.5 9.8 17.0 20.3 10.5 3.5 3.7 7.7 15.5 15.5 19.7 18.0 11.7 31.3 0.3 16.0 16.9 2.1 42.2 16.0 10.3 5.9 14.2 8.2 6.1 14.1 7.3 8.5 7.4 16.2 2.1 22.9 2.4 7.1 10.5 5.9 17.3 0.0 0.9 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 2.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.1 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 8.3 5.8 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.9 0.1 1.2 0.5 0.0 0.0 0.1 0.0 0.1 4.5 0.6 1.3 2.2 0.8 1.4 11.9 4.6 2.4 0.6 12.8 6.7 5.9 1.9 1.8 1.7 1.6 2.6 0.8 17.9 17.8 24.6 21.7 17.0 20.3 15.5 15.5 16.0 14.1 16.2 17.3 1.5 6.4 15.5 56.2 79.1 36.3 55.9 8.2 58.6 175.2 34.8 47.0 14.0 42.9 20.7 23.9 143.9 0.5 7.2 0.1 0.0 33.5 2.9 0.2 1.6 4.2 7.7 4.4 95.3 28.5 0.3 10.8 2.0 0.2 24.6 9.5 6.4 4.9 0.2 95.9 90.1 4.4 8.2 1.0 2.2 4.5 33.5 2.2 12.4 17.8 3.3 52.3 4.1 101.0 50.4 14.6 1.4 46.6 18.6 38.6 3.1 6.6 19.4 204.9 0.0 9.0 7.0 51.0 39.5 15.9 39.6 0.5 19.8 1.1 1.5 38.2 RIDA "HRSP12, P14.5, PSP, UK114" ENSG00000132541 "Reactive intermediate imine deaminase A homolog" P52758 8 98102344-98117171 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "kidney: 496.2;liver: 1536.9" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 1579.1" "Group enriched" "Detected in all" 5 "liver cancer: 162.2;renal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 191.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022856, HPA023489" Enhanced NA NA 5000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA022856: AB_1858253, HPA023489: AB_1858252" "unprognostic (1.67e-2)" "unprognostic (3.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (4.16e-1)" "unprognostic (2.20e-2)" "prognostic favorable (9.61e-6)" "unprognostic (6.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (4.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-2)" "unprognostic (1.51e-2)" 50.1 48.4 93.1 11.4 96.4 7.5 19.1 95.5 131.7 11.2 83.8 24.5 30.5 8.4 22.7 14.3 9.4 22.7 32.3 89.2 95.0 496.2 1536.9 9.5 10.1 91.6 97.8 23.4 27.0 24.6 10.0 10.8 95.5 19.3 24.6 26.6 16.4 11.6 40.0 10.6 21.8 10.8 92.6 7.4 24.8 17.2 100.0 11.2 15.9 41.0 12.3 15.5 7.9 91.0 44.0 37.5 29.3 36.6 65.5 50.4 33.0 39.7 28.0 26.4 31.0 51.4 28.4 62.5 49.6 29.4 34.5 30.8 65.4 56.9 52.5 22.3 28.6 45.0 25.6 55.6 29.9 17.6 7.0 44.4 19.5 36.6 39.9 32.4 34.2 65.3 82.7 12.9 35.5 57.8 35.6 50.1 47.0 191.4 67.8 41.0 21.7 18.4 64.6 31.6 32.2 15.7 25.5 17.4 29.2 37.4 44.5 23.5 20.9 20.6 12.5 33.7 16.3 31.2 46.1 30.9 35.0 39.0 13.2 0.2 9.0 5.6 6.6 7.8 8.7 13.8 9.4 10.1 11.1 11.5 12.0 13.0 1.9 10.3 8.3 8.5 13.9 8.1 93.1 96.4 95.5 131.7 89.2 95.0 91.6 97.8 95.5 92.6 100.0 91.0 7.8 25.6 22.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 13.8 15.1 0.0 0.0 1.8 47.8 0.0 31.1 3.2 0.0 285.7 19.7 0.0 25.1 12.3 5.0 0.0 0.0 0.0 8.5 29.9 7.9 0.0 9.4 2.5 17.7 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 5.7 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.8 0.0 0.0 1579.1 5.8 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 14.4 6.3 22.3 0.0 0.0 RIMS1 "CORD7, KIAA0340, RAB3IP2, RIM, RIM1" ENSG00000079841 "Regulating synaptic membrane exocytosis 1" Q86UR5 6 71886703-72403143 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "brain: 365.0" "Group enriched" "Detected in many" 4 "Excitatory neurons: 653.2;Inhibitory neurons: 572.7;Oligodendrocyte precursor cells: 323.2" "Cancer enhanced" "Detected in single" "prostate cancer: 0.7" "Region enriched" "Detected in many" 16 "cerebellum: 365.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 5.2;EFO-21: 8.8;LHCN-M2: 10.0;RPTEC TERT1: 15.0;SH-SY5Y: 10.7;TIME: 5.4;U-138 MG: 5.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 352.9" HPA076565 Enhanced NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA076565: " "unprognostic (1.34e-3)" "unprognostic (3.47e-1)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (6.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.73e-2)" "unprognostic (8.57e-2)" "unprognostic (2.85e-1)" "unprognostic (7.76e-4)" "unprognostic (2.42e-2)" "unprognostic (2.29e-1)" "unprognostic (7.91e-2)" "unprognostic (2.76e-1)" "unprognostic (5.74e-2)" "unprognostic (1.07e-2)" 0.2 1.2 5.5 0.8 14.1 0.0 0.5 365.0 22.5 0.3 0.0 0.3 0.7 0.2 0.0 2.1 0.0 3.9 0.1 16.3 8.4 0.0 0.0 0.2 0.0 0.3 9.0 0.0 0.4 1.6 2.4 0.0 20.8 3.0 0.1 7.4 1.1 0.3 0.2 0.2 0.4 0.7 0.0 0.0 1.4 4.1 5.4 0.0 0.0 0.9 0.0 0.1 0.0 13.2 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.2 1.4 0.0 0.2 0.0 0.0 5.2 8.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.4 1.6 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.5 15.0 0.0 0.4 10.7 0.0 0.0 0.0 0.3 0.7 0.0 5.4 5.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 14.1 365.0 22.5 16.3 8.4 0.3 9.0 20.8 0.0 5.4 13.2 0.2 0.0 0.5 120.2 0.0 0.0 0.2 2.1 0.0 69.1 3.0 3.2 1.4 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 15.2 0.0 0.9 2.5 0.0 0.0 653.2 0.8 0.0 1.8 0.0 0.0 1.3 0.3 3.6 0.0 0.0 62.2 572.7 0.0 2.0 0.0 0.0 10.2 0.3 0.3 3.6 16.9 0.0 109.7 0.0 323.2 76.5 0.5 0.0 1.5 0.0 1.0 0.0 0.4 3.6 9.9 0.0 1.3 2.7 21.3 13.6 0.0 0.1 0.0 0.1 0.3 0.0 0.5 RIPPLY1 ENSG00000147223 "Ripply transcriptional repressor 1" Q0D2K3 X 106900063-106903341 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 3.4;liver: 5.8" "Group enriched" "Detected in some" 9 "Hepatocytes: 4.3;Proximal tubular cells: 1.2" "Cancer enhanced" "Detected in some" "liver cancer: 2.2;renal cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "RH-30: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA052284 Uncertain "Intracellular and membrane" NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "HPA052284: AB_2681785" "unprognostic (1.48e-1)" "unprognostic (4.35e-2)" "unprognostic (1.67e-1)" "unprognostic (9.52e-3)" "unprognostic (7.00e-3)" "unprognostic (1.13e-2)" "unprognostic (1.66e-3)" "unprognostic (1.50e-1)" "unprognostic (2.42e-1)" "unprognostic (5.37e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-1)" "unprognostic (2.49e-3)" "unprognostic (1.97e-1)" "unprognostic (1.97e-1)" "unprognostic (1.97e-3)" "unprognostic (1.31e-1)" 0.1 0.4 0.1 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.9 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.1 3.4 5.8 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.8 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 RLN1 H1 ENSG00000107018 "Relaxin 1" P04808 9 5334930-5339876 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "prostate: 23.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.8;Enteroendocrine cells: 4.8;Prostatic glandular cells: 10.6;Spermatocytes: 2.4;Spermatogonia: 3.1" "Cancer enriched" "Detected in some" 106 "prostate cancer: 67.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HEL: 1.2" "Secreted to blood" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 35: Glandular cells - Unknown function" "unprognostic (7.12e-6)" "unprognostic (2.32e-1)" "unprognostic (7.29e-2)" "unprognostic (1.98e-1)" "unprognostic (2.22e-2)" "unprognostic (1.04e-1)" "unprognostic (4.32e-2)" "unprognostic (3.44e-1)" "unprognostic (5.14e-2)" "unprognostic (4.08e-4)" "unprognostic (8.15e-2)" "unprognostic (2.89e-4)" "unprognostic (8.82e-3)" "unprognostic (3.23e-2)" "unprognostic (3.23e-2)" "unprognostic (1.53e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.9 0.2 0.0 0.5 1.0 0.8 0.2 2.8 0.1 0.0 0.0 0.7 0.3 0.0 0.0 0.6 1.6 0.7 0.2 0.1 4.8 1.7 0.0 0.5 0.4 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.4 10.6 0.0 0.4 1.0 0.8 0.0 0.2 0.1 2.4 3.1 0.0 0.1 1.1 1.6 0.1 0.2 0.3 RLN2 "bA12D24.1.1, bA12D24.1.2, H2, RLXH2" ENSG00000107014 "Relaxin 2" P04090 9 5299864-5304716 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 5.2" "Cell type enhanced" "Detected in many" "Early spermatids: 13.0;Muller glia cells: 9.6;Spermatocytes: 17.3;Syncytiotrophoblasts: 13.5" "Group enriched" "Detected in some" 5 "breast cancer: 2.0;prostate cancer: 6.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 26 "gdT-cell: 1.4;MAIT T-cell: 4.2;memory B-cell: 1.9;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.3;naive B-cell: 1.4;naive CD4 T-cell: 4.0;naive CD8 T-cell: 3.0;NK-cell: 3.5;T-reg: 1.3" "Group enriched" "Detected in many" 33 "B-cells: 1.9;NK-cells: 3.5;T-cells: 4.2" "Cell line enhanced" "Detected in some" "Daudi: 5.6;HEL: 21.9;T-47d: 6.1;U-266/84: 10.2" "Secreted to blood" NA NA 24400 10000 "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.63e-3)" "unprognostic (1.26e-1)" "unprognostic (2.09e-3)" "unprognostic (2.84e-1)" "unprognostic (2.03e-2)" "unprognostic (9.99e-2)" "unprognostic (1.48e-1)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (2.50e-3)" "unprognostic (9.18e-2)" "unprognostic (1.74e-6)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (1.88e-2)" "unprognostic (8.41e-4)" 0.4 0.0 0.4 1.4 0.5 0.3 2.3 0.6 0.7 0.4 0.5 0.5 0.0 0.5 0.3 0.3 5.2 0.2 0.5 0.4 0.5 1.9 0.0 0.7 2.8 0.6 0.5 0.1 0.5 4.2 2.9 0.6 0.6 3.9 0.4 2.9 0.3 0.6 0.0 0.4 0.5 0.2 0.5 0.9 0.5 2.8 0.5 2.7 0.8 0.2 2.3 0.2 0.1 0.5 3.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.5 1.0 0.3 1.6 5.6 0.4 0.0 0.0 0.9 0.0 2.8 0.7 4.4 2.0 21.9 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.5 0.0 0.0 0.2 0.1 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.0 0.6 2.7 3.0 0.0 0.6 0.1 0.2 6.1 0.1 0.2 0.0 0.5 0.0 0.1 1.3 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.2 1.9 2.8 2.3 0.0 1.4 4.0 3.0 0.0 3.5 0.0 0.0 1.3 0.8 0.4 0.5 0.6 0.7 0.4 0.5 0.6 0.5 0.6 0.5 0.5 0.5 0.8 3.2 0.6 0.3 2.6 0.5 2.3 1.5 1.2 1.5 3.8 3.0 1.9 1.5 1.2 1.8 0.0 6.3 1.3 0.1 7.9 2.8 13.0 3.3 0.3 0.8 3.6 1.7 0.4 1.5 2.3 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.6 3.3 0.9 1.7 2.0 0.0 0.0 5.3 0.6 0.1 0.0 1.0 0.8 9.6 4.1 0.0 0.9 0.8 0.2 0.4 0.5 1.0 0.1 1.4 5.0 1.7 0.0 0.6 0.4 17.3 5.1 1.4 1.3 13.5 3.4 0.0 1.5 0.5 RLN3 "H3, RXN3, ZINS4" ENSG00000171136 "Relaxin 3" Q8WXF3 19 14028148-14031551 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "parathyroid gland: 1.6;testis: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "midbrain: 11.7;pons and medulla: 27.2" "Region enriched" "Detected in many" 9 "pons: 23.6" "Secreted to blood" NA NA 60000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (1.96e-2)" "unprognostic (2.54e-2)" "unprognostic (3.94e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RMDN1 "CGI-90, FAM82B, FLJ20665, RMD1" ENSG00000176623 "Regulator of microtubule dynamics 1" Q96DB5 8 86468257-86514357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026495 Approved Supported "Actin filaments,Centrosome" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Centrosome "Actin filaments" "HPA026495: AB_1848414" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" "unprognostic (1.46e-1)" "unprognostic (3.13e-3)" "unprognostic (1.76e-1)" "unprognostic (1.50e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-2)" "unprognostic (1.68e-1)" "unprognostic (3.02e-1)" "unprognostic (2.09e-1)" "unprognostic (1.60e-1)" "prognostic favorable (8.51e-4)" "unprognostic (2.08e-1)" "unprognostic (7.15e-2)" "unprognostic (4.71e-3)" "unprognostic (3.47e-1)" 35.6 26.1 25.8 20.9 30.1 24.7 24.3 30.4 27.8 15.5 25.3 26.7 28.7 17.6 19.8 29.4 21.1 22.5 63.0 23.0 29.5 51.7 56.8 23.4 30.3 29.8 29.7 17.0 17.5 26.3 12.9 18.9 30.0 21.2 29.0 30.9 16.4 20.7 71.7 32.8 29.2 20.2 28.3 25.2 30.6 26.4 29.6 23.0 50.4 70.5 31.5 20.1 16.3 30.5 64.0 27.1 31.3 17.8 60.3 97.8 38.5 45.9 41.1 35.8 34.6 32.2 39.9 76.2 38.1 38.2 33.2 61.0 39.8 46.0 42.1 64.6 31.9 40.2 32.8 82.1 32.1 18.4 1.0 53.3 42.6 47.6 72.9 63.9 81.6 44.3 42.4 40.7 57.5 57.3 65.1 8.6 15.9 111.3 67.5 36.6 43.6 78.9 42.5 39.3 14.8 32.8 38.2 149.2 67.6 32.5 83.9 33.6 44.6 39.5 64.0 50.8 28.2 52.4 46.5 59.7 51.2 28.7 54.4 16.4 38.5 94.2 26.6 50.7 31.1 42.2 27.1 31.3 45.2 30.8 22.3 29.0 15.5 39.0 70.3 51.3 43.2 30.7 25.8 30.1 30.4 27.8 23.0 29.5 29.8 29.7 30.0 28.3 29.6 30.5 24.0 41.7 39.0 38.8 23.8 13.5 13.2 40.1 22.2 14.5 16.8 15.0 117.3 20.0 42.4 20.2 16.7 42.5 29.9 22.2 49.0 42.9 97.8 28.3 26.6 24.3 10.2 27.3 22.5 53.0 57.1 24.0 32.1 24.8 1.3 18.9 21.8 57.7 53.7 20.2 29.9 20.6 18.3 40.1 14.8 77.1 13.1 28.3 16.0 33.7 48.5 27.4 21.6 42.3 51.9 45.8 17.2 9.1 21.8 9.2 45.7 73.0 34.4 21.5 0.0 19.9 32.9 65.7 33.5 31.0 15.5 28.5 21.6 53.1 26.9 15.2 RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 9121.6" "Cell type enhanced" "Detected in many" "Adipocytes: 826.6;Alveolar cells type 1: 929.5;Alveolar cells type 2: 818.4;Gastric mucus-secreting cells: 821.1;Hepatic stellate cells: 650.3;Hofbauer cells: 1583.4;Intestinal goblet cells: 663.8;Macrophages: 632.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 286.8;OE19: 67.4;RT4: 114.2;TIME: 179.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 1100000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" 694.2 501.3 336.6 131.3 466.1 6.2 353.3 404.4 556.1 203.9 294.9 378.4 176.7 139.4 112.0 194.0 232.0 406.4 377.7 351.3 380.9 253.0 54.5 775.9 187.8 438.9 408.3 190.6 9121.6 60.6 43.9 897.4 403.7 83.9 425.2 3.1 168.0 149.7 127.6 118.1 201.8 285.6 357.3 353.1 1003.5 977.5 465.4 177.6 119.7 280.6 68.8 374.7 107.9 533.7 0.0 1.4 0.5 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 6.7 0.0 0.3 1.7 0.0 2.2 0.6 0.0 1.4 0.0 0.1 0.1 5.3 0.1 0.8 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 286.8 0.0 31.4 0.4 0.0 0.0 0.3 2.0 1.2 67.4 0.0 0.2 0.1 1.5 0.2 114.2 1.2 1.4 0.0 0.8 0.3 2.0 0.3 0.1 179.3 0.0 2.7 1.8 0.3 0.6 0.1 0.1 4.6 0.1 3.8 1.6 9.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.0 5.0 0.0 2.4 336.6 466.1 404.4 556.1 351.3 380.9 438.9 408.3 403.7 357.3 465.4 533.7 826.6 929.5 818.4 1.6 11.1 35.6 1.0 1.9 15.9 0.1 6.2 11.7 59.8 27.1 174.0 16.5 0.0 12.9 5.7 261.8 0.0 8.8 20.0 3.8 1.9 581.7 48.7 28.0 0.5 315.2 14.6 58.4 821.1 3.4 25.2 103.8 650.3 7.9 1583.4 1.7 0.8 663.8 8.2 267.9 197.5 57.1 32.0 632.8 40.9 36.5 3.4 0.8 0.0 1.0 232.3 286.8 246.7 10.9 7.5 1.4 81.7 0.9 34.9 2.7 98.6 20.7 31.4 16.4 6.6 16.6 28.1 25.9 10.6 392.8 162.9 3.8 RNASE10 "RAH1, RNASE9" ENSG00000182545 "Ribonuclease A family member 10 (inactive)" Q5GAN6 14 20505537-20511169 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Fertilization" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "head and neck cancer: 2.0;testis cancer: 1.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SiHa: 7.2;U-2 OS: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052593 Uncertain "Secreted - unknown location" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA052593: AB_2681878" "unprognostic (2.48e-3)" "unprognostic (2.22e-1)" "unprognostic (2.46e-2)" "unprognostic (1.17e-1)" "unprognostic (1.74e-1)" "unprognostic (5.91e-3)" "unprognostic (5.03e-3)" "unprognostic (5.58e-3)" "unprognostic (4.20e-2)" "unprognostic (3.04e-1)" "unprognostic (1.98e-3)" "unprognostic (1.11e-1)" "unprognostic (7.88e-4)" "unprognostic (1.58e-1)" "unprognostic (3.62e-1)" "unprognostic (8.76e-2)" "unprognostic (2.58e-1)" 2.1 1.8 3.2 1.6 3.0 1.1 0.4 2.8 4.3 0.5 2.8 0.7 1.6 2.0 1.1 1.1 1.1 0.6 0.4 3.2 2.4 0.9 0.8 1.6 0.8 3.8 3.0 1.1 0.4 0.4 0.5 0.8 3.2 1.2 0.4 0.5 0.9 0.7 2.0 2.5 1.7 0.5 1.8 1.3 1.1 1.9 3.1 0.5 0.7 0.2 0.4 0.7 0.5 5.2 4.4 2.0 0.9 1.9 0.2 0.4 2.8 0.2 0.4 0.1 0.3 0.9 1.2 0.5 1.3 0.5 0.6 2.3 0.0 0.3 0.1 1.7 0.7 0.0 1.5 0.6 0.5 0.1 2.0 0.7 1.5 0.1 2.3 0.4 1.0 0.7 1.0 2.3 0.0 1.2 0.7 1.1 0.5 0.6 0.2 3.3 0.3 2.6 0.7 1.8 1.1 1.4 7.2 1.7 0.9 0.9 1.6 0.7 0.4 0.7 10.8 0.9 0.8 2.2 0.9 0.2 0.8 0.6 0.9 1.1 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.3 0.3 0.0 0.0 3.2 3.0 2.8 4.3 3.2 2.4 3.8 3.0 3.2 1.8 3.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 RNASE11 "C14orf6, RAJ1" ENSG00000173464 "Ribonuclease A family member 11 (inactive)" Q8TAA1 14 20583559-20609884 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "epididymis: 444.4" "Group enriched" "Detected in some" 63 "Early spermatids: 32.1;Late spermatids: 57.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA003724 Uncertain "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA003724: AB_1079817" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 444.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 61.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 57.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNASE12 RAI1 ENSG00000258436 "Ribonuclease A family member 12 (inactive)" Q5GAN4 14 20590193-20590823 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 300 "epididymis: 862.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044175, HPA059465" Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA044175: AB_10960390, HPA059465: AB_2732638" 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 862.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNASE13 RAL1 ENSG00000206150 "Ribonuclease A family member 13 (inactive)" Q5GAN3 14 21032818-21034807 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "epididymis: 306.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (2.54e-1)" "unprognostic (2.52e-1)" "unprognostic (2.86e-1)" "unprognostic (8.40e-2)" "unprognostic (1.93e-1)" "unprognostic (7.15e-2)" "unprognostic (1.63e-3)" "unprognostic (5.20e-4)" "unprognostic (1.47e-2)" 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 306.9 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.9 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.1 0.3 0.3 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "bone marrow: 1713.7" "Cell type enhanced" "Detected in some" "Erythroid cells: 30.7;Kupffer cells: 174.3;Macrophages: 82.2;monocytes: 54.6" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 457.5;eosinophil: 1352.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 1352.6" "Group enriched" "Detected in some" 303 "HL-60: 539.0;NB-4: 539.8;THP-1: 1405.4;U-937: 1295.9" HPA044983 Enhanced "Secreted to blood" NA NA 200000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 7.1 6.0 3.0 9.1 2.8 1713.7 1.7 2.9 5.5 2.3 4.4 2.2 0.2 2.1 0.3 0.9 5.7 2.6 4.0 2.8 4.2 1.7 4.6 12.2 1.9 5.4 4.1 1.5 1.7 0.5 1.7 1.8 4.4 1.7 0.7 1.7 1.9 0.2 0.7 2.9 1.4 9.7 4.5 35.1 2.1 0.7 4.2 14.8 0.9 0.6 0.6 5.2 1.4 6.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 0.0 539.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 539.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 1405.4 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.7 0.0 1295.9 0.0 457.5 109.0 1352.6 0.4 19.3 0.8 0.3 0.4 0.0 191.8 0.4 0.4 0.4 9.8 0.1 2.8 2.6 0.1 39.9 3.0 2.8 2.9 5.5 2.8 4.2 5.4 4.1 4.4 4.5 4.2 6.3 0.2 3.2 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.4 0.0 1.9 0.0 0.5 0.0 0.0 1.3 0.0 30.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.4 2.2 13.0 0.0 0.0 0.0 0.0 174.3 0.7 1.7 0.3 82.2 0.0 0.0 54.6 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 19.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 RNASE3 "ECP, RAF1, RNS3" ENSG00000169397 "Ribonuclease A family member 3" P12724 14 20891399-20892348 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 95 "bone marrow: 934.3" "Cell type enhanced" "Detected in some" "Early spermatids: 22.9;Erythroid cells: 5.9;Kupffer cells: 4.5;Late spermatids: 10.9;Macrophages: 3.0;Rod photoreceptor cells: 3.5" "Cancer enriched" "Detected in single" 8 "glioma: 2.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 22 "eosinophil: 304.6" "Lineage enriched" "Detected in many" 22 "granulocytes: 304.6" "Cell line enhanced" "Detected in some" "HL-60: 150.4;NB-4: 51.1;THP-1: 63.6;U-937: 301.8" HPA056183 Enhanced "Secreted to blood" NA NA 4200000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA056183: AB_2683059" "unprognostic (2.54e-2)" "unprognostic (6.61e-2)" "unprognostic (1.84e-1)" "unprognostic (2.50e-1)" "unprognostic (1.37e-2)" "unprognostic (8.21e-2)" "unprognostic (6.45e-2)" "unprognostic (9.20e-3)" "unprognostic (1.20e-1)" "unprognostic (9.21e-2)" "unprognostic (8.62e-7)" "unprognostic (6.29e-2)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (2.37e-1)" 0.4 0.4 0.5 0.5 0.5 934.3 0.1 0.5 1.2 0.1 0.3 0.2 0.0 0.1 0.3 0.1 0.3 0.3 0.2 0.5 1.0 0.2 2.0 2.7 0.7 1.1 0.7 0.2 0.1 0.0 0.3 0.6 0.9 0.2 0.1 3.8 1.2 0.1 0.1 1.7 0.1 1.0 1.0 9.8 0.1 1.8 0.5 9.4 0.1 0.0 0.0 0.3 0.1 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 150.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 63.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 301.8 0.0 11.3 8.8 304.6 0.0 1.2 0.1 0.0 0.0 0.0 14.1 0.0 0.0 0.0 4.3 0.0 0.5 1.6 0.0 4.4 0.5 0.5 0.5 1.2 0.5 1.0 1.1 0.7 0.9 1.0 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.1 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.5 0.0 10.9 0.3 3.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 RNASE4 RAB1 ENSG00000258818 "Ribonuclease A family member 4" P34096 14 20684560-20701216 "Plasma proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 478.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 67.3;Gastric mucus-secreting cells: 47.4;Hepatocytes: 55.8;Intestinal goblet cells: 110.0" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 92.6;ASC TERT1: 107.2;Hep G2: 136.9;HSkMC: 63.1;OE19: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 61000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 27: Mucus-secreting cells - Mucin production" "unprognostic (1.07e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-2)" "unprognostic (3.18e-4)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "prognostic favorable (9.62e-5)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (6.88e-2)" "unprognostic (3.71e-2)" "unprognostic (1.29e-1)" "unprognostic (3.46e-1)" "unprognostic (2.54e-2)" "unprognostic (1.57e-1)" "unprognostic (9.16e-2)" "unprognostic (4.27e-2)" 106.4 7.8 5.5 8.9 5.7 1.2 96.6 5.4 8.3 95.6 8.5 56.5 22.0 59.2 37.0 20.1 77.3 55.6 44.1 5.5 8.1 40.3 478.8 40.3 12.2 6.9 6.6 111.7 41.0 14.7 12.5 5.7 6.9 76.7 65.2 4.7 74.8 45.8 14.1 47.4 41.9 25.9 6.7 11.8 84.7 10.6 5.3 5.8 26.5 31.5 10.6 65.3 75.9 7.8 2.7 12.1 2.6 0.1 92.6 107.2 0.5 10.5 23.8 1.4 4.5 3.4 4.1 0.1 2.9 24.6 6.2 2.5 1.4 2.6 1.7 17.2 1.8 0.3 2.9 136.9 10.2 1.3 0.6 63.1 5.8 1.6 10.3 34.6 12.6 4.2 0.1 12.2 6.9 1.5 1.0 0.2 0.5 92.3 10.3 0.6 2.1 3.6 2.9 2.4 0.1 0.5 5.0 2.3 2.6 4.2 3.4 0.2 13.3 3.0 1.7 4.1 0.3 2.6 3.5 0.4 4.7 1.3 2.7 0.2 24.1 0.1 0.8 1.2 1.0 5.3 1.5 0.6 13.8 4.9 0.3 0.6 0.6 0.6 0.1 3.3 3.3 8.4 5.5 5.7 5.4 8.3 5.5 8.1 6.9 6.6 6.9 6.7 5.3 7.8 1.8 38.5 19.1 2.0 3.4 2.8 1.7 2.5 11.4 0.0 9.9 2.5 0.2 28.6 4.7 3.7 0.0 0.2 0.3 30.4 0.0 34.4 0.2 0.1 0.8 4.0 67.3 8.4 0.1 22.2 0.4 39.2 47.4 0.8 1.3 0.3 5.0 55.8 1.6 0.0 0.2 110.0 2.0 6.2 4.0 0.3 12.5 3.6 3.6 1.9 2.7 1.3 1.0 0.0 0.9 12.8 33.2 4.1 5.9 1.7 41.7 10.2 11.6 0.3 0.0 2.6 8.1 0.2 0.1 10.2 4.1 0.4 0.8 0.1 39.6 1.5 RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 108.0;dendritic cells: 221.7;Hofbauer cells: 207.9;Kupffer cells: 551.2;Langerhans cells: 198.4;Macrophages: 270.3;monocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 65.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" 25.2 29.5 8.0 59.6 7.5 27.5 24.0 7.8 13.6 31.6 10.0 27.7 17.3 10.6 78.4 16.0 11.3 47.7 11.7 7.3 10.9 12.2 21.1 29.6 110.5 13.6 10.1 9.9 8.4 9.0 4.3 44.8 11.9 7.9 34.0 1.8 11.2 17.2 2.0 8.6 33.4 23.6 10.8 62.1 14.9 4.5 12.6 43.8 5.5 6.0 84.5 43.3 5.1 19.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 2.1 2.1 0.0 0.0 0.0 0.0 0.0 1.7 4.7 0.6 0.2 0.0 0.0 1.9 4.6 0.0 0.0 0.0 0.2 0.0 65.6 1.1 0.7 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 441.1 537.3 12.8 5.3 124.8 12.0 324.7 13.6 5.6 513.3 410.3 6.4 1.0 199.0 36.7 2.0 1238.8 1.1 329.8 8.0 7.5 7.8 13.6 7.3 10.9 13.6 10.1 11.9 10.8 12.6 19.5 1.6 6.4 7.5 0.0 108.0 4.5 0.2 0.0 1.8 0.0 1.4 2.8 0.6 14.3 1.2 0.0 0.0 1.1 221.7 2.6 0.0 0.0 0.8 0.1 0.0 3.8 0.0 12.0 0.0 0.0 1.6 1.4 1.1 0.2 0.0 0.0 8.6 3.3 207.9 0.0 0.0 0.5 2.0 551.2 198.4 4.8 2.8 270.3 21.4 1.9 115.8 0.0 9.2 0.0 0.0 0.0 12.6 0.7 52.4 0.2 0.4 0.5 0.2 0.4 13.1 0.6 0.6 0.1 0.7 0.6 3.8 2.2 7.8 0.0 3.4 1.2 RNASE7 RAE1 ENSG00000165799 "Ribonuclease A family member 7" Q9H1E1 14 21042316-21044234 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 74.9;lymphoid tissue: 24.1;skin 1: 27.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.2;Cholangiocytes: 8.6;Prostatic glandular cells: 7.3;Urothelial cells: 27.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 24.7;hTCEpi: 10.3;hTERT-HME1: 53.3" "HPA005690, CAB062560, CAB068225" Enhanced "Secreted in other tissues" NA NA 280000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "CAB062560: AB_2665595, CAB068225: AB_2665594, HPA005690: AB_1079819" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" "unprognostic (5.84e-2)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (8.27e-2)" "unprognostic (7.80e-2)" "unprognostic (8.73e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.17e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "unprognostic (3.24e-1)" "unprognostic (3.42e-1)" 0.1 0.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 74.9 0.0 6.6 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.5 0.0 4.7 0.5 0.3 27.9 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.0 0.0 0.0 24.1 0.2 9.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 24.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.1 53.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 30.2 1.5 0.0 0.0 0.1 2.4 0.5 8.6 0.4 0.0 0.0 1.5 0.0 0.1 0.0 4.5 0.9 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.0 0.0 0.3 5.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 7.3 0.0 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 5.3 0.3 0.0 0.2 27.2 RNASE8 RAE2 ENSG00000173431 "Ribonuclease A family member 8" Q8TDE3 14 21057822-21058455 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 229 "salivary gland: 54.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 54.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNASE9 "h461, RAK1" ENSG00000188655 "Ribonuclease A family member 9 (inactive)" P60153 14 20556093-20560931 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 985 "epididymis: 98.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNASEH1 ENSG00000171865 "Ribonuclease H1" O60930 2 3541430-3558333 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA034817, HPA043037" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA034817: , HPA043037: AB_2678280" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "unprognostic (8.81e-3)" "unprognostic (4.32e-3)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.83e-6)" "unprognostic (9.43e-2)" "unprognostic (8.46e-3)" "unprognostic (6.38e-2)" "unprognostic (2.29e-3)" "unprognostic (2.67e-1)" "unprognostic (4.06e-2)" "unprognostic (2.34e-2)" "unprognostic (2.11e-1)" "unprognostic (3.06e-2)" "unprognostic (2.23e-3)" 10.6 8.7 9.7 9.5 10.6 11.4 9.7 8.2 12.3 8.5 6.8 7.8 7.2 11.7 11.3 9.6 7.8 7.5 13.0 11.1 11.2 7.1 8.1 7.9 10.2 10.1 9.1 8.2 8.7 9.1 3.3 7.9 10.1 9.3 9.5 8.7 7.7 11.8 15.3 9.9 7.8 13.3 9.2 9.0 6.9 7.0 11.7 10.3 9.5 15.0 10.9 8.5 4.7 10.5 11.9 21.4 22.1 22.5 24.9 23.2 17.2 29.0 30.6 24.8 16.5 19.4 13.0 33.6 13.7 31.5 18.8 14.7 32.6 23.2 30.9 12.4 17.5 33.1 18.9 27.5 35.5 42.0 23.3 23.5 24.9 24.2 29.3 18.5 21.5 54.8 33.0 19.4 31.1 9.3 32.7 27.3 34.7 20.6 17.0 26.9 32.0 34.3 21.0 19.7 33.3 48.9 17.8 15.9 27.5 16.7 10.3 22.9 24.8 24.1 11.5 24.7 40.7 36.1 37.5 43.9 43.2 35.1 37.5 0.1 0.6 1.3 1.3 1.2 2.2 1.1 1.0 1.7 0.7 0.6 1.0 2.1 0.5 0.4 1.2 1.5 0.4 0.7 9.7 10.6 8.2 12.3 11.1 11.2 10.1 9.1 10.1 9.2 11.7 10.5 15.6 22.4 6.9 9.1 30.7 7.5 26.1 21.0 13.6 25.7 14.9 12.6 25.9 11.5 14.7 3.7 20.9 32.7 25.4 14.4 37.2 44.3 5.1 9.6 20.8 20.1 15.0 13.5 11.8 48.7 44.3 20.2 17.9 11.0 27.3 17.9 16.8 18.0 30.8 35.3 10.7 16.4 14.2 18.8 8.9 3.4 13.7 16.2 10.6 10.3 32.3 17.5 30.9 7.5 9.8 48.3 9.9 26.4 41.7 50.2 16.6 28.6 14.1 18.8 19.7 23.6 23.4 21.0 27.5 17.8 12.1 36.5 18.9 27.7 15.9 37.9 RNASET2 "bA514O12.3, FLJ10907, RNASE6PL" ENSG00000026297 "Ribonuclease T2" O00584 6 166922113-166957191 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Endonuclease, Hydrolase, Lyase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 490.2;Glandular and luminal cells: 761.3;Hofbauer cells: 382.2;Kupffer cells: 484.7;Macrophages: 418.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "THP-1: 497.9" "HPA029013, HPA066509" Approved "Secreted to blood" NA NA 15000000 "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA029013: AB_10602922, HPA066509: AB_2685682" "unprognostic (4.18e-2)" "unprognostic (2.57e-1)" "unprognostic (1.44e-1)" "unprognostic (1.06e-1)" "unprognostic (4.13e-2)" "unprognostic (9.33e-2)" "unprognostic (1.76e-2)" "unprognostic (1.30e-1)" "unprognostic (1.15e-2)" "unprognostic (8.11e-2)" "unprognostic (1.79e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (1.70e-14)" "unprognostic (5.03e-2)" "unprognostic (7.34e-2)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" 34.9 35.0 50.1 68.6 50.4 124.3 50.2 52.2 65.9 161.5 52.3 74.0 57.6 49.1 140.7 24.8 134.6 69.6 19.8 49.5 53.5 31.2 52.4 47.2 117.4 68.2 54.3 36.2 144.7 40.7 26.3 43.5 66.2 51.9 89.9 8.3 112.8 94.1 7.3 25.4 65.4 27.8 61.9 195.1 72.9 13.3 59.1 43.8 76.7 12.1 86.9 54.9 32.2 79.8 12.8 14.2 12.6 37.8 57.0 40.6 8.4 15.8 21.2 7.3 7.4 33.7 19.9 11.1 149.8 41.3 16.7 41.0 20.8 18.6 4.3 15.9 35.1 10.2 20.6 84.6 19.1 152.7 37.3 23.9 33.6 4.3 2.7 30.4 10.1 21.7 20.9 94.5 10.9 44.9 12.6 109.5 6.4 140.0 13.0 25.0 16.6 131.7 136.3 9.9 4.4 28.7 32.0 100.4 8.3 22.3 13.1 497.9 19.3 14.9 9.8 43.7 13.5 15.0 19.5 1.4 32.3 149.2 10.3 116.9 185.6 674.8 29.1 277.0 53.4 136.7 159.9 72.3 226.4 119.6 128.4 41.4 438.9 30.7 368.8 369.3 90.8 179.8 50.1 50.4 52.2 65.9 49.5 53.5 68.2 54.3 66.2 61.9 59.1 79.8 21.8 19.2 29.3 10.1 270.1 43.3 116.4 45.1 72.3 10.5 97.0 95.1 9.5 47.1 28.0 38.6 0.0 63.4 286.8 133.7 23.5 59.2 10.3 490.2 78.9 44.9 75.4 27.6 13.6 27.4 58.8 45.8 80.0 761.3 71.7 38.6 19.2 20.0 382.2 13.5 37.1 204.0 24.4 484.7 187.7 11.3 35.4 418.2 58.7 113.4 146.1 24.4 64.9 14.6 1.7 74.1 324.8 29.3 158.6 61.2 178.5 19.6 19.0 7.1 26.3 31.9 18.6 10.0 23.1 58.3 34.5 27.8 149.2 15.3 193.0 103.9 RNF10 "KIAA0262, RIE2" ENSG00000022840 "Ring finger protein 10" Q8N5U6 12 120533480-120577588 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 286.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052643 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm Mitochondria "HPA052643: AB_2681897" "unprognostic (1.54e-1)" "unprognostic (3.04e-1)" "unprognostic (5.40e-2)" "unprognostic (2.83e-3)" "unprognostic (1.09e-2)" "unprognostic (3.58e-2)" "prognostic unfavorable (5.30e-5)" "unprognostic (5.02e-2)" "unprognostic (3.06e-1)" "unprognostic (1.68e-1)" "unprognostic (1.93e-1)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-1)" "unprognostic (4.10e-2)" "unprognostic (2.40e-1)" 79.5 104.3 99.0 52.7 101.2 184.8 68.1 97.2 135.0 63.9 108.8 90.1 58.8 61.6 96.1 103.0 58.5 50.1 191.2 101.7 98.4 108.3 81.7 74.4 53.6 99.0 102.9 65.6 75.2 75.8 71.3 65.9 97.8 69.0 65.8 76.6 68.1 61.7 307.2 77.8 61.2 77.8 99.3 78.7 81.0 96.8 100.9 57.9 60.7 208.8 69.5 73.2 69.3 107.2 109.7 141.6 68.3 109.3 130.9 103.0 80.6 100.7 113.9 81.8 86.4 117.1 49.3 129.5 89.4 167.3 64.0 73.9 126.6 136.5 116.0 127.5 71.0 132.1 77.5 123.0 175.3 120.0 89.5 105.5 155.0 115.1 156.8 141.8 168.5 95.7 134.2 86.7 124.3 125.3 79.4 131.1 104.0 101.7 139.9 69.8 87.5 185.4 164.4 221.1 66.9 72.7 140.0 89.5 78.9 94.2 144.2 68.6 134.8 59.3 65.7 95.5 65.9 74.7 146.8 90.8 97.5 80.2 65.0 154.2 53.8 173.8 45.5 45.8 48.9 35.7 44.7 52.4 60.0 31.2 39.5 40.6 118.0 46.1 54.3 30.7 60.7 52.9 99.0 101.2 97.2 135.0 101.7 98.4 99.0 102.9 97.8 99.3 100.9 107.2 56.2 25.6 32.6 30.3 54.0 61.9 51.1 27.1 52.3 39.9 63.8 42.9 99.3 32.9 28.4 47.8 22.9 62.1 58.9 93.5 164.4 49.7 72.7 54.1 53.2 45.9 49.2 286.5 43.1 58.7 69.4 47.8 64.7 78.9 36.8 42.0 42.8 48.8 36.9 55.5 42.9 50.3 34.6 52.5 63.1 41.7 56.8 54.7 56.9 16.9 48.7 43.3 56.7 32.2 52.4 59.8 49.1 54.9 71.2 63.1 73.8 70.0 21.6 54.5 52.6 52.3 55.0 118.0 55.2 74.5 65.8 111.8 59.1 74.1 47.3 77.8 RNF135 MGC13061 ENSG00000181481 "Ring finger protein 135" Q8IUD6 17 30970984-30999911 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 73.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 63.3" "Low region specificity" "Detected in all" "HPA021576, HPA052404" Approved Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA021576: AB_1856331, HPA052404: AB_2681817" "unprognostic (1.13e-1)" "unprognostic (1.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.33e-2)" "unprognostic (2.68e-2)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "unprognostic (4.60e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (6.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-1)" "unprognostic (4.47e-1)" 20.9 12.9 11.1 13.5 12.5 11.6 18.6 11.2 14.2 16.0 15.1 17.5 13.6 13.3 16.5 22.4 15.7 9.6 8.5 10.4 11.3 21.6 8.6 15.5 13.9 13.9 13.2 12.6 13.5 16.8 5.6 18.1 12.4 14.0 18.0 2.3 15.2 15.2 7.4 26.2 13.9 13.7 12.8 25.8 11.9 5.1 16.4 7.9 15.8 10.1 12.6 14.8 17.3 13.8 12.7 25.6 1.5 25.4 34.0 28.5 22.7 9.7 14.9 9.4 8.4 0.0 9.4 11.5 14.8 19.0 17.0 17.0 13.2 12.1 7.8 10.0 5.6 4.8 8.1 0.0 24.3 12.8 10.7 27.7 63.3 10.1 33.5 16.1 15.8 0.0 0.0 34.9 15.6 17.0 0.1 13.5 10.5 25.7 14.4 27.9 0.0 39.2 13.6 18.2 9.8 0.5 14.9 5.9 14.9 16.6 39.4 20.2 13.3 0.0 3.5 15.6 11.5 0.4 1.3 7.3 16.5 22.1 13.3 25.3 61.6 31.3 12.8 57.3 7.2 28.4 6.8 6.8 46.4 28.4 3.7 6.2 54.0 13.9 70.2 17.1 10.1 29.2 11.1 12.5 11.2 14.2 10.4 11.3 13.9 13.2 12.4 12.8 16.4 13.8 14.1 3.2 5.9 7.8 14.1 9.3 13.4 16.8 22.2 0.1 13.1 15.0 4.0 7.2 7.8 11.0 0.0 47.5 10.5 23.4 29.4 9.9 0.4 14.5 12.8 13.2 4.9 11.2 0.8 18.6 37.1 13.2 5.6 12.4 1.3 14.1 25.4 2.7 51.1 0.0 1.0 12.0 8.2 73.9 8.4 1.6 16.8 35.5 16.0 26.2 45.3 3.9 19.6 9.0 0.7 11.9 13.1 15.4 9.0 22.2 27.5 49.3 10.4 0.6 26.3 8.2 14.2 0.7 4.0 24.1 14.6 43.6 7.5 10.6 14.6 11.2 RNF146 "dactylidin, dJ351K20.1, DKFZp434O1427" ENSG00000118518 "Ring finger protein 146" Q9NTX7 6 127266682-127288567 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027158, HPA027209" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA027158: AB_10600772, HPA027209: AB_10602312" "unprognostic (8.22e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-2)" "unprognostic (1.37e-1)" "unprognostic (5.47e-3)" "unprognostic (1.87e-1)" "unprognostic (6.74e-2)" "prognostic favorable (5.26e-5)" "unprognostic (2.65e-2)" "prognostic favorable (7.32e-4)" "unprognostic (4.04e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "unprognostic (2.15e-2)" 52.9 37.0 49.5 32.4 56.0 10.6 42.7 79.4 61.2 48.1 36.2 40.5 21.9 57.4 60.8 25.3 42.4 38.6 46.9 50.7 51.6 37.1 31.8 38.7 35.1 53.2 52.1 49.5 23.3 40.0 33.3 51.8 56.8 31.7 30.9 48.1 31.2 34.5 114.9 29.5 31.1 45.9 55.2 47.1 29.9 31.3 52.5 24.3 47.1 91.5 33.3 36.9 34.3 61.5 13.2 16.2 60.3 53.6 54.7 54.3 22.2 43.5 69.0 22.8 32.4 21.3 19.3 23.6 30.3 35.7 36.2 16.4 18.1 20.4 32.9 27.6 16.0 30.3 21.8 30.0 54.0 18.0 20.6 47.6 42.1 26.1 51.1 52.5 40.6 23.2 33.0 22.5 50.7 25.2 17.9 32.0 22.1 8.1 17.1 22.6 15.7 12.1 32.4 14.3 36.0 36.6 17.1 23.6 27.7 35.5 16.1 60.8 48.3 39.7 13.1 41.8 31.7 32.3 22.0 15.6 30.5 31.0 38.5 27.5 30.0 26.6 14.3 32.4 14.7 17.4 12.2 16.3 22.8 17.9 11.0 15.5 37.0 19.8 40.1 11.7 15.0 16.1 49.5 56.0 79.4 61.2 50.7 51.6 53.2 52.1 56.8 55.2 52.5 61.5 24.6 35.3 29.3 35.6 23.7 17.7 14.3 15.1 18.8 34.7 16.9 14.7 38.9 31.5 16.7 9.2 4.2 29.0 14.7 13.5 41.1 28.0 52.5 15.7 29.5 30.5 20.4 12.8 53.5 15.8 27.2 50.6 7.1 11.5 22.2 28.1 31.4 30.5 26.3 30.3 54.5 12.1 38.7 68.4 24.6 45.4 69.6 29.9 46.2 42.2 31.1 41.1 28.8 56.3 76.5 18.0 17.0 66.5 9.3 26.3 15.7 51.7 23.9 20.9 32.9 36.2 31.9 41.7 24.9 15.0 20.0 38.4 20.8 36.0 10.9 25.9 RNF150 KIAA1214 ENSG00000170153 "Ring finger protein 150" Q9ULK6 4 140859807-141212877 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Excitatory neurons: 184.5;Inhibitory neurons: 174.3;Microglial cells: 114.3;Oligodendrocyte precursor cells: 285.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 19.7;fHDF/TERT166: 27.1;SH-SY5Y: 37.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037987 Uncertain "Intracellular and membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA037987: AB_10669512" "prognostic favorable (1.41e-4)" "unprognostic (1.95e-2)" "unprognostic (8.26e-3)" "unprognostic (2.41e-2)" "unprognostic (3.31e-1)" "unprognostic (5.38e-2)" "unprognostic (2.38e-2)" "unprognostic (5.88e-2)" "unprognostic (1.09e-1)" "unprognostic (9.32e-2)" "unprognostic (3.10e-3)" "unprognostic (3.07e-1)" "unprognostic (4.02e-2)" "unprognostic (3.88e-3)" "unprognostic (9.68e-2)" "unprognostic (1.32e-3)" "unprognostic (2.41e-2)" 11.3 12.4 6.8 1.7 12.5 0.3 3.1 7.5 7.7 8.0 0.0 16.5 1.0 11.9 10.8 6.8 12.4 3.4 14.9 7.7 8.1 8.3 0.9 1.3 3.3 1.3 1.3 10.8 2.0 0.5 7.8 1.9 6.1 8.3 3.8 31.8 31.7 11.1 18.7 0.9 3.7 12.2 1.9 5.4 4.0 1.4 5.6 2.0 6.2 12.5 3.1 6.5 3.9 2.0 0.3 0.5 4.8 4.2 19.7 1.4 0.2 6.8 3.5 2.5 1.2 0.0 0.1 0.0 0.9 27.1 0.1 0.1 9.8 0.1 1.3 0.1 4.6 0.0 8.9 0.0 0.1 0.0 0.0 1.6 0.1 0.0 0.2 1.6 0.0 4.8 0.0 0.1 0.9 0.1 4.7 0.2 2.2 0.0 1.8 2.6 12.4 0.1 2.8 0.0 2.0 37.0 0.7 0.3 1.9 2.5 0.1 0.1 0.1 12.6 5.2 8.7 3.1 0.3 0.1 0.0 0.2 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 12.5 7.5 7.7 7.7 8.1 1.3 1.3 6.1 1.9 5.6 2.0 0.8 0.0 0.5 65.6 0.0 1.1 0.7 0.3 3.4 53.9 3.1 7.4 72.5 1.5 2.2 11.0 112.6 1.3 0.0 0.1 1.9 0.4 4.6 17.8 43.9 2.7 1.8 0.0 184.5 0.5 0.1 10.0 0.0 22.8 0.0 11.4 2.2 0.2 0.7 26.9 174.3 0.0 0.0 0.6 2.9 2.7 28.6 2.0 0.0 114.3 0.0 13.4 0.0 285.5 5.7 0.1 0.0 18.0 0.0 1.1 0.0 1.0 0.2 69.1 13.1 34.5 17.4 0.0 2.0 0.5 0.6 0.4 0.4 47.6 0.0 0.1 RNF165 "Ark2C, ARKL2, RNF111L2" ENSG00000141622 "Ring finger protein 165" Q6ZSG1 18 46326809-46463140 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.6;retina: 18.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 44.0;Cone photoreceptor cells: 100.1;Excitatory neurons: 47.4;Horizontal cells: 80.8;Inhibitory neurons: 34.4;NK-cells: 41.2;Oligodendrocyte precursor cells: 35.7;Rod photoreceptor cells: 49.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 10.1;HaCaT: 7.3;HeLa: 7.5;RPMI-8226: 6.4;SCLC-21H: 13.9;SH-SY5Y: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041615, HPA047798" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Plasma membrane" "HPA041615: AB_2677582, HPA047798: AB_2680158" "unprognostic (6.46e-3)" "unprognostic (7.25e-2)" "unprognostic (4.55e-2)" "unprognostic (1.24e-5)" "unprognostic (3.43e-1)" "unprognostic (4.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.04e-3)" "unprognostic (1.95e-1)" "unprognostic (1.23e-1)" "unprognostic (2.07e-1)" "unprognostic (1.87e-5)" "unprognostic (3.53e-3)" "unprognostic (1.90e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" 0.6 0.5 3.1 0.3 3.7 0.3 0.7 7.6 6.4 0.6 0.0 0.4 0.0 0.2 1.9 1.2 1.2 0.3 1.0 4.7 0.2 1.6 5.2 0.3 0.2 0.0 0.3 0.0 0.3 2.4 4.1 0.2 0.0 2.2 0.1 18.2 0.8 1.3 1.5 1.2 0.3 0.1 0.1 2.0 0.2 0.5 1.3 0.9 4.0 0.8 0.4 0.3 0.5 1.9 1.6 0.1 10.1 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 7.3 0.5 1.0 0.0 0.0 1.1 0.1 7.5 0.0 0.0 3.4 0.0 0.0 0.8 0.0 0.0 0.4 0.0 2.3 0.0 0.2 0.0 0.0 2.6 0.9 1.7 0.4 1.3 2.7 0.6 6.4 0.7 2.2 13.9 13.2 2.0 0.0 0.0 0.9 0.3 0.5 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 3.8 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 3.1 3.7 7.6 6.4 4.7 0.2 0.0 0.3 0.0 0.1 1.3 1.9 9.1 3.2 1.7 1.6 0.3 2.7 9.5 12.9 28.5 44.0 2.9 7.2 8.4 1.5 2.8 0.0 100.1 0.2 10.0 0.2 3.9 0.0 3.8 1.5 9.3 5.0 0.0 0.0 47.4 0.0 0.3 2.4 0.0 0.6 0.0 0.0 1.8 8.9 0.1 80.8 34.4 0.0 2.0 1.9 1.3 5.1 2.5 0.4 1.8 1.9 0.3 5.0 41.2 35.7 1.8 0.1 0.0 4.1 0.4 5.0 0.1 0.1 0.6 49.1 0.0 4.5 0.7 0.4 0.9 3.7 2.0 0.3 3.2 3.2 0.0 2.4 RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved Approved "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "Mitotic spindle, Centriolar satellite" "HPA049810: AB_2680894" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favorable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favorable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" 75.0 110.6 141.9 53.0 146.7 69.0 73.1 146.4 179.9 93.2 138.6 111.5 66.6 94.9 76.4 122.1 84.3 45.3 131.8 141.5 146.4 106.7 184.2 77.5 64.5 146.3 145.4 87.4 115.1 105.8 96.8 50.7 146.3 95.0 65.7 98.1 92.5 70.5 152.9 127.8 100.5 52.8 142.4 113.8 111.8 110.6 150.3 98.1 93.4 94.2 71.6 106.7 90.4 153.3 102.6 143.1 61.1 73.7 132.8 68.7 92.7 63.4 76.1 119.7 93.4 96.2 43.3 71.5 120.3 93.5 63.9 147.5 103.2 114.8 86.1 74.5 166.1 121.9 164.4 94.9 100.6 59.0 245.0 79.6 176.5 129.8 116.2 74.6 77.2 101.0 49.9 237.5 96.2 66.3 92.8 70.6 75.4 102.0 86.8 62.8 61.9 91.5 137.3 77.4 49.2 61.1 56.0 92.9 81.9 83.1 87.3 55.9 49.5 76.6 48.3 66.8 119.3 79.5 88.0 23.7 98.4 80.6 77.9 108.4 88.8 236.9 195.3 94.0 153.4 100.4 148.0 195.7 73.9 98.7 103.2 152.2 219.8 118.8 117.7 75.9 153.0 177.0 141.9 146.7 146.4 179.9 141.5 146.4 146.3 145.4 146.3 142.4 150.3 153.3 36.9 0.0 3.9 12.4 54.3 68.6 44.4 65.8 51.8 43.2 56.6 44.7 15.8 77.2 38.9 49.7 20.9 120.1 64.7 65.2 56.7 78.5 59.6 29.8 25.1 36.4 31.8 60.6 11.3 66.7 139.7 36.3 36.2 32.2 14.0 26.3 45.7 95.1 58.4 18.5 11.2 45.7 65.1 41.3 43.6 86.5 48.7 36.1 39.2 6.5 53.1 46.9 114.4 10.1 17.9 60.7 44.9 53.8 59.1 32.6 108.2 64.0 31.1 32.3 39.5 28.4 35.1 127.1 106.7 61.4 83.3 125.2 82.5 37.2 59.6 48.0 RNF220 "C1orf164, FLJ10597" ENSG00000187147 "Ring finger protein 220" Q5VTB9 1 44405194-44651724 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 121.3" "Cell type enriched" "Detected in all" 7 "Oligodendrocytes: 2136.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-937: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027577, HPA027578" Approved Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 32: U-937 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA027577: AB_2672339, HPA027578: AB_10601482" "unprognostic (3.12e-2)" "unprognostic (1.24e-1)" "unprognostic (3.49e-2)" "unprognostic (2.56e-1)" "unprognostic (2.94e-2)" "unprognostic (6.96e-3)" "prognostic unfavorable (2.35e-6)" "unprognostic (1.55e-1)" "unprognostic (8.47e-2)" "unprognostic (2.13e-1)" "unprognostic (2.14e-3)" "unprognostic (2.96e-2)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.51e-2)" "unprognostic (1.98e-1)" "unprognostic (1.37e-3)" "unprognostic (6.46e-2)" 7.5 5.9 37.9 7.3 67.0 10.8 6.8 49.1 49.3 7.4 0.4 9.1 7.8 8.9 5.9 6.6 8.1 2.9 8.7 36.2 45.1 6.6 5.2 5.7 5.9 64.1 53.3 7.6 7.0 5.7 7.1 6.2 63.0 5.9 3.9 7.5 7.4 4.5 24.3 8.6 7.7 5.5 38.1 6.9 6.6 8.2 68.3 7.1 6.3 10.1 5.8 7.0 7.0 121.3 11.6 5.4 22.9 7.8 8.7 7.9 17.1 13.4 12.3 10.1 14.9 9.3 11.2 22.3 11.6 10.8 14.4 7.5 25.8 11.0 13.7 28.0 22.9 30.9 17.9 16.3 14.1 22.0 15.2 8.7 24.7 11.3 17.9 8.4 5.9 11.6 23.1 10.7 6.3 8.1 21.8 16.7 24.9 12.6 12.2 18.3 13.5 15.9 6.5 7.1 10.3 12.7 11.4 7.8 17.4 7.9 5.8 38.1 9.1 10.7 11.4 10.2 25.1 24.4 25.2 16.0 8.7 69.5 6.5 0.9 0.8 1.2 1.2 0.7 0.9 0.8 0.3 1.6 1.3 1.2 0.7 0.6 0.6 0.8 0.5 2.5 1.3 0.6 37.9 67.0 49.1 49.3 36.2 45.1 64.1 53.3 63.0 38.1 68.3 121.3 16.2 9.6 13.4 66.3 26.9 15.2 13.4 13.2 30.1 25.1 24.7 20.8 22.0 25.8 10.4 23.9 25.0 17.3 33.7 29.0 17.6 17.9 13.1 23.4 20.7 17.2 18.0 41.9 21.9 28.7 24.5 16.7 19.4 20.5 10.8 18.8 17.9 31.4 25.7 23.5 12.9 24.3 22.4 29.3 9.8 16.2 19.3 21.3 12.4 298.9 23.9 19.2 15.5 7.1 2136.9 25.3 20.9 13.9 26.1 22.5 26.5 35.6 8.2 18.3 6.6 23.5 14.8 30.6 31.3 25.1 17.5 10.1 26.1 17.6 26.7 20.5 RNF34 "FLJ21786, RIF, RIFF" ENSG00000170633 "Ring finger protein 34" Q969K3 12 121400041-121430623 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 134.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074151 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA074151: AB_2686668" "unprognostic (3.54e-1)" "unprognostic (4.83e-2)" "unprognostic (1.90e-1)" "unprognostic (6.10e-2)" "unprognostic (9.92e-2)" "unprognostic (2.55e-2)" "prognostic unfavorable (6.72e-8)" "unprognostic (3.39e-1)" "unprognostic (9.99e-2)" "unprognostic (1.60e-2)" "unprognostic (5.87e-3)" "unprognostic (2.80e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.09e-1)" "unprognostic (3.55e-1)" "unprognostic (5.55e-3)" "prognostic favorable (3.02e-4)" 13.7 10.8 25.5 23.6 29.7 13.4 13.4 31.6 32.2 11.6 21.8 19.2 19.5 13.7 13.5 14.9 12.5 17.3 18.4 26.8 28.6 11.3 13.0 12.9 34.3 26.0 26.6 14.7 13.8 13.3 13.7 11.5 26.7 10.5 15.6 19.0 13.9 13.5 59.5 15.7 18.3 16.7 24.7 23.3 18.4 24.6 26.6 26.8 13.9 36.8 26.4 19.0 11.9 32.7 45.4 53.8 34.7 36.3 26.8 24.5 43.2 47.5 42.2 46.3 35.3 67.3 16.9 64.9 35.3 51.3 24.6 31.8 52.6 29.8 41.0 95.3 30.8 75.4 37.7 62.5 32.1 65.7 50.4 21.9 39.6 40.2 34.7 26.4 49.3 37.9 58.0 29.3 46.0 35.7 57.5 95.7 44.5 26.6 48.4 54.0 45.1 38.1 32.0 53.2 50.7 33.0 59.4 21.8 36.6 31.6 38.0 49.1 39.5 39.5 28.4 34.6 37.8 51.2 92.8 70.5 28.2 45.4 40.6 83.7 42.1 91.2 72.4 48.4 74.1 77.1 83.2 76.8 40.4 65.0 71.1 71.1 65.2 76.2 53.3 34.3 106.3 68.3 25.5 29.7 31.6 32.2 26.8 28.6 26.0 26.6 26.7 24.7 26.6 32.7 14.5 16.0 16.2 15.3 22.9 17.5 18.7 23.4 13.6 13.9 16.5 13.2 22.0 27.1 18.9 9.2 4.2 26.1 30.9 19.0 37.2 32.7 23.5 13.7 15.3 17.3 40.8 24.8 34.3 27.3 38.8 16.1 15.8 13.9 17.7 19.0 17.2 11.2 21.2 13.5 32.7 15.8 30.5 18.0 14.9 10.7 17.1 14.0 17.8 13.1 35.0 23.6 46.4 9.5 45.5 26.2 17.2 18.0 27.9 17.0 20.5 19.9 18.7 21.4 19.7 11.1 25.0 134.0 73.9 15.3 16.1 24.2 34.3 18.5 21.2 25.7 RNFT2 "FLJ14627, TMEM118" ENSG00000135119 "Ring finger protein, transmembrane 2" Q96EX2 12 116738178-116853631 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.8;pituitary gland: 5.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.9;Early spermatids: 49.3;Excitatory neurons: 22.7;Inhibitory neurons: 28.7;Late spermatids: 56.4;Oligodendrocyte precursor cells: 18.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/84: 14.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064161 Enhanced Approved Nucleoplasm,Cytosol No No "Cluster 11: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA064161: AB_2685202" "unprognostic (1.56e-1)" "unprognostic (1.79e-2)" "unprognostic (1.54e-1)" "unprognostic (3.59e-1)" "unprognostic (3.98e-1)" "unprognostic (3.10e-2)" "unprognostic (8.14e-5)" "unprognostic (8.62e-2)" "unprognostic (6.28e-3)" "unprognostic (2.58e-1)" "unprognostic (9.25e-3)" "unprognostic (2.75e-1)" "unprognostic (7.61e-3)" "unprognostic (2.86e-2)" "unprognostic (1.35e-1)" "unprognostic (8.36e-3)" "unprognostic (4.01e-4)" 0.4 1.0 9.8 0.5 9.8 1.0 0.2 5.7 13.8 0.2 2.9 0.3 0.5 0.2 0.8 0.4 0.3 0.4 0.4 10.6 8.4 0.7 0.1 0.3 1.1 11.8 7.6 0.4 0.2 0.4 5.1 1.0 11.9 0.2 0.3 4.9 0.6 0.2 0.6 0.6 0.5 0.2 4.2 0.8 0.3 3.7 7.9 1.4 0.5 0.1 1.2 0.2 0.1 9.3 1.3 7.3 2.9 9.8 0.1 0.1 6.8 0.5 0.5 1.6 1.2 3.3 1.2 6.5 1.9 0.1 2.2 1.3 7.8 0.6 0.9 7.0 4.6 1.1 5.5 2.4 1.1 0.5 4.9 0.2 0.1 3.6 0.8 0.9 0.3 4.4 8.0 2.1 0.1 4.0 7.6 1.1 4.5 1.9 1.3 4.1 1.5 3.4 2.0 1.2 5.0 4.8 1.8 0.8 1.9 2.6 5.0 1.7 0.4 1.0 4.5 2.2 2.5 3.6 14.9 8.5 4.0 0.5 0.6 1.1 0.2 0.2 0.3 0.1 0.1 0.7 0.3 0.3 0.1 0.8 0.6 0.7 0.7 0.5 0.3 0.7 0.2 0.2 9.8 9.8 5.7 13.8 10.6 8.4 11.8 7.6 11.9 4.2 7.9 9.3 0.9 0.0 0.5 11.8 2.2 0.0 0.3 0.2 0.0 17.9 0.7 0.3 1.2 1.5 0.2 7.3 16.7 3.1 0.3 0.5 0.0 0.9 49.3 0.7 0.3 1.9 4.2 0.4 22.7 0.2 3.0 0.6 1.1 0.6 0.0 3.8 0.4 0.2 2.2 10.1 28.7 0.8 2.0 1.9 0.8 56.4 0.6 0.7 1.8 3.7 1.0 5.5 0.0 18.6 7.0 0.6 0.1 1.5 2.0 0.2 0.6 1.0 1.4 10.3 0.0 0.7 0.9 3.8 5.2 0.2 0.0 1.6 0.5 1.1 0.8 0.2 RNLS "C10orf59, FLJ11218, renalase" ENSG00000184719 "Renalase, FAD dependent amine oxidase" Q5VYX0 10 88273864-88584530 "Enzymes, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 103.0;Inhibitory neurons: 101.1;Oligodendrocyte precursor cells: 51.8;Oligodendrocytes: 61.8;Proximal tubular cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 18.3;fHDF/TERT166: 17.1;HSkMC: 19.5" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 10500000000 "Cluster 7: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.27e-2)" "unprognostic (9.16e-2)" "unprognostic (1.27e-1)" "unprognostic (2.58e-1)" "unprognostic (1.46e-3)" "unprognostic (1.99e-1)" "unprognostic (2.01e-1)" "unprognostic (2.29e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (3.98e-1)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "unprognostic (7.74e-3)" "unprognostic (1.37e-2)" "unprognostic (9.80e-2)" "unprognostic (1.71e-1)" 7.1 13.4 2.0 2.8 2.4 2.2 6.7 6.1 3.5 7.4 7.2 7.6 5.5 5.0 5.3 4.9 6.1 5.5 11.8 2.0 2.9 16.6 8.7 3.0 3.8 5.0 6.6 5.8 8.2 9.0 5.3 2.0 5.2 7.0 8.3 4.8 6.0 3.9 11.8 4.3 5.6 3.5 3.4 2.8 6.7 5.3 2.7 2.5 9.1 9.8 4.0 4.7 4.4 3.2 18.3 8.2 0.3 0.1 2.4 2.8 0.0 5.1 0.5 2.7 2.3 1.0 5.2 0.0 8.0 17.1 0.0 2.4 0.0 0.9 2.2 3.8 0.1 2.9 5.1 0.2 11.2 0.0 0.5 19.5 1.4 10.2 0.1 0.3 5.7 0.1 1.4 9.2 0.1 6.3 0.0 3.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 4.3 0.1 0.1 4.0 12.4 4.9 2.2 8.9 1.3 2.5 4.1 6.3 3.9 5.3 8.4 0.2 0.0 9.8 0.0 0.0 2.1 1.2 2.3 3.6 1.7 2.4 1.7 1.6 3.1 2.2 1.8 1.4 0.1 2.7 2.3 2.7 0.9 1.8 2.0 2.4 6.1 3.5 2.0 2.9 5.0 6.6 5.2 3.4 2.7 3.2 1.2 3.2 1.5 32.0 5.5 3.2 6.8 5.7 4.0 6.5 5.5 3.9 16.7 4.3 5.8 1.8 2.1 2.0 3.2 6.2 23.5 6.4 8.9 3.8 3.1 1.3 5.4 4.6 103.0 9.6 0.5 6.2 7.1 3.2 1.3 2.2 2.5 10.1 6.5 5.0 101.1 5.5 2.0 4.7 3.8 4.3 1.5 3.8 3.6 40.3 3.7 6.8 3.1 51.8 61.8 4.2 8.9 6.4 3.9 4.4 8.5 43.1 1.6 5.7 0.0 4.6 4.6 4.7 8.2 10.4 5.5 1.6 3.0 2.9 7.2 6.9 ROMO1 "bA353C18.2, C20orf52, MTGMP" ENSG00000125995 "Reactive oxygen species modulator 1" P60602 20 35699272-35700984 "Predicted intracellular proteins, Transporters" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 1349.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012782 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA012782: AB_1845685" "unprognostic (1.55e-1)" "unprognostic (3.86e-2)" "unprognostic (3.00e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-2)" "unprognostic (1.27e-3)" "unprognostic (5.84e-2)" "unprognostic (6.15e-2)" "unprognostic (1.21e-1)" "unprognostic (3.65e-2)" "unprognostic (7.35e-2)" "unprognostic (6.55e-2)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (2.70e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-2)" 126.3 185.8 164.8 71.6 170.7 112.3 125.8 174.7 216.3 112.3 182.8 131.7 99.8 113.0 81.6 185.6 102.9 50.8 246.2 165.5 169.8 188.4 206.2 99.8 79.2 171.0 170.0 111.3 134.7 122.3 163.6 63.0 170.5 126.4 66.3 33.0 133.9 79.6 259.2 122.0 105.1 51.7 170.2 104.6 126.0 121.6 175.1 102.3 122.5 168.9 59.3 108.6 119.7 176.4 304.5 493.7 164.5 202.1 125.3 169.2 269.2 165.7 196.2 256.6 251.0 1196.7 263.5 154.6 370.6 125.5 380.3 320.6 88.5 438.3 64.9 84.6 615.1 267.2 547.2 1349.5 259.4 166.6 134.7 216.2 204.3 182.1 133.1 118.5 209.7 285.9 224.6 309.7 124.7 966.0 373.0 456.6 251.8 327.6 867.8 246.5 319.0 342.3 246.9 516.1 229.3 236.0 288.6 546.5 306.6 150.0 502.6 353.8 172.5 425.0 240.1 281.1 279.8 504.6 481.5 409.3 371.0 130.9 249.7 602.8 590.1 459.5 398.5 511.9 378.4 587.2 408.8 393.7 573.0 523.1 346.7 384.9 330.0 391.8 486.2 1054.9 538.0 726.4 164.8 170.7 174.7 216.3 165.5 169.8 171.0 170.0 170.5 170.2 175.1 176.4 168.1 102.5 187.2 2.3 147.5 118.3 87.5 339.7 124.7 28.7 235.9 237.9 662.8 264.5 256.3 257.5 8.4 284.8 101.0 691.8 403.0 364.1 23.8 334.5 192.2 150.9 328.1 152.3 2.2 571.6 256.0 194.8 253.8 268.5 193.2 125.9 166.7 641.1 219.9 20.2 2.1 412.9 203.4 157.9 164.3 50.9 130.5 165.0 236.5 3.7 266.4 176.1 108.1 1.0 4.8 567.4 574.0 128.2 323.2 124.8 573.0 753.7 355.8 39.5 118.3 109.7 262.4 283.9 225.4 270.7 153.2 326.9 141.5 64.4 387.0 115.6 ROR1 NTRKR1 ENSG00000185483 "Receptor tyrosine kinase like orphan receptor 1" Q01973 1 63774017-64181498 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Receptor, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 26.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Astrocytes: 81.0;Inhibitory neurons: 69.7;Microglial cells: 36.5;Oligodendrocytes: 109.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 40.5;ASC TERT1: 50.3;CACO-2: 36.8;HHSteC: 38.3;HSkMC: 41.6;NTERA-2: 43.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 7700000 "Cluster 40: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (5.15e-2)" "unprognostic (1.19e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-2)" "unprognostic (6.24e-2)" "unprognostic (1.61e-1)" "unprognostic (7.11e-3)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "unprognostic (3.84e-1)" "unprognostic (3.20e-2)" "unprognostic (2.02e-2)" "unprognostic (3.64e-3)" "unprognostic (1.48e-2)" "unprognostic (1.52e-1)" "unprognostic (5.87e-2)" "unprognostic (5.15e-2)" 4.4 1.1 0.6 2.2 1.4 0.4 3.7 3.0 0.8 7.5 4.6 4.5 2.2 7.1 1.4 5.2 2.5 5.2 7.5 0.7 0.6 2.3 0.5 7.0 1.2 0.7 0.9 8.3 5.5 26.9 0.5 3.1 0.5 5.4 4.0 1.5 1.2 6.4 2.3 2.3 1.7 7.7 0.3 3.2 6.4 1.5 1.2 2.5 1.4 1.6 1.1 4.2 2.3 1.1 15.5 12.2 5.9 0.8 40.5 50.3 4.0 2.9 8.3 1.6 4.3 36.8 4.9 0.3 6.6 7.2 2.9 3.2 0.1 2.9 1.1 0.0 3.7 0.0 1.6 0.5 38.3 0.0 0.0 41.6 10.9 21.7 25.2 8.4 0.7 0.5 0.0 0.3 11.0 0.2 0.2 0.1 43.0 11.3 6.1 0.2 0.2 9.8 8.7 0.3 3.4 13.6 0.8 0.2 6.4 19.9 0.1 0.0 8.4 3.3 5.7 23.0 6.2 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.6 1.4 3.0 0.8 0.7 0.6 0.7 0.9 0.5 0.3 1.2 1.1 1.1 51.3 10.5 81.0 1.8 3.8 2.2 0.5 29.0 4.7 3.0 2.0 11.4 1.5 1.3 1.8 0.0 0.2 0.1 1.3 0.0 5.6 9.6 1.2 9.2 1.8 21.5 0.0 11.6 15.2 1.0 14.5 16.8 1.9 0.0 1.1 0.7 0.0 7.6 0.0 69.7 2.2 2.0 0.6 4.9 8.1 27.7 0.5 3.6 36.5 0.0 5.3 0.0 3.5 109.9 15.3 0.8 14.7 0.1 1.4 0.0 3.4 0.8 0.3 6.6 6.8 8.5 1.4 1.8 11.5 4.5 0.3 0.2 0.3 3.3 0.8 RPIA ENSG00000153574 "Ribose 5-phosphate isomerase A" P49247 2 88691673-88750929 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.6" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 234.3;Erythroid cells: 167.9;Syncytiotrophoblasts: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042620, HPA057954" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 2500000 "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles, Plasma membrane" "HPA042620: AB_10793980, HPA057954: AB_2683563" "unprognostic (3.35e-2)" "unprognostic (1.35e-2)" "unprognostic (6.96e-2)" "unprognostic (9.24e-2)" "unprognostic (4.31e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (8.70e-2)" "unprognostic (8.82e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.53e-6)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-2)" "unprognostic (8.79e-3)" 17.2 11.0 7.4 19.6 7.6 89.6 16.0 8.3 8.9 13.4 8.0 22.7 22.1 13.2 9.5 24.1 14.6 11.7 16.0 7.3 8.2 10.6 7.8 12.2 28.0 7.8 7.5 13.7 17.9 7.4 8.2 33.8 7.5 8.9 23.0 4.1 15.9 8.1 29.9 11.9 18.9 12.5 7.8 19.2 18.9 9.6 8.0 40.4 9.7 17.1 32.4 16.5 12.5 7.9 29.7 17.0 33.7 26.9 23.4 23.9 73.8 16.1 15.1 26.1 17.8 61.1 38.2 150.1 34.3 18.7 35.8 17.7 42.4 13.5 40.9 71.9 55.3 60.2 11.0 60.7 23.7 111.5 42.4 22.1 11.2 23.3 35.9 13.0 37.4 78.7 65.7 25.3 24.8 46.5 123.4 97.2 30.7 97.6 27.7 63.5 40.1 36.8 21.7 47.1 24.0 27.4 19.4 24.8 39.3 18.3 13.5 45.3 21.4 15.5 40.7 51.2 46.7 19.7 17.2 149.3 15.9 99.4 22.5 10.6 16.0 36.4 16.9 16.7 21.4 31.4 23.5 25.1 22.7 23.5 33.4 27.8 3.9 21.9 21.9 10.9 22.0 20.6 7.4 7.6 8.3 8.9 7.3 8.2 7.8 7.5 7.5 7.8 8.0 7.9 38.9 12.8 13.2 4.6 43.2 37.3 21.3 31.2 21.6 8.7 22.2 18.2 13.7 14.3 22.7 20.2 2.1 234.3 37.1 20.6 9.8 21.7 8.1 28.0 23.3 35.0 19.2 167.9 13.3 34.2 98.9 23.5 31.1 43.2 21.6 30.7 24.3 7.1 43.8 13.5 15.7 26.9 26.4 23.1 33.9 4.0 19.9 23.7 40.9 11.2 32.4 5.2 60.8 13.6 13.3 22.8 28.1 18.8 35.8 41.7 20.6 18.7 10.1 4.8 19.7 19.8 18.0 28.4 33.4 37.6 40.9 225.6 38.8 37.8 58.5 43.7 RPL23A L23A ENSG00000198242 "Ribosomal protein L23a" P62750 17 28719985-28724359 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA051754, HPA077474" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 86000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli fibrillar center, Endoplasmic reticulum, Cytosol" "HPA051754: AB_2681593, HPA077474: AB_2686841" "unprognostic (1.33e-2)" "unprognostic (1.96e-1)" "unprognostic (1.61e-1)" "unprognostic (2.97e-1)" "unprognostic (9.79e-2)" "unprognostic (7.76e-2)" "unprognostic (1.91e-3)" "unprognostic (1.23e-1)" "unprognostic (9.64e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (5.16e-6)" "unprognostic (3.91e-2)" "unprognostic (1.54e-1)" "unprognostic (3.98e-3)" "unprognostic (2.68e-1)" 1584.8 1113.1 654.3 671.5 688.0 1394.2 1570.3 652.4 1022.2 2187.2 625.1 1445.1 612.6 1394.1 718.6 1571.9 1634.3 535.3 1187.3 618.4 650.0 1099.0 883.0 1093.0 1433.2 673.2 651.5 3435.1 1784.0 525.5 1098.5 674.5 679.4 1319.5 821.4 343.6 1355.9 639.7 2007.1 2167.8 1341.4 670.2 718.7 1621.7 1365.0 394.3 691.1 970.1 1098.0 887.1 1529.3 1516.5 1724.7 701.9 1011.7 2016.2 1187.9 1478.2 1541.3 2460.3 1167.5 919.9 1609.3 1530.9 1285.0 2069.6 945.7 2272.0 842.9 1288.6 794.8 1336.2 1604.1 2059.1 1570.9 1207.4 4393.8 1090.0 1875.4 2228.4 1393.9 2286.0 1078.5 2415.4 2592.8 1218.4 1907.0 2198.5 1679.1 1024.9 1440.9 1494.0 1555.3 1668.7 2566.5 3014.5 1145.8 2554.4 1212.9 1485.1 2158.1 2703.9 1672.0 2029.6 1233.6 1432.9 656.5 4676.5 2224.2 1655.3 2336.4 2637.5 1009.1 833.0 1177.1 985.4 1663.8 1819.6 1831.8 1323.2 1314.2 1241.1 939.6 1095.3 1931.7 552.4 4031.6 2107.3 5926.1 6793.2 5786.8 5255.4 2964.7 5683.7 6315.4 5951.4 244.7 4162.0 1738.1 3784.3 4293.0 7336.1 654.3 688.0 652.4 1022.2 618.4 650.0 673.2 651.5 679.4 718.7 691.1 701.9 987.8 862.2 1387.4 42.1 4276.8 5192.7 5364.3 4497.6 1889.4 237.4 3483.7 2581.2 292.2 2254.7 2254.3 864.4 70.9 4486.2 3010.4 1253.0 3083.4 2444.1 968.0 1089.8 2060.3 2031.0 1846.3 1943.9 13.5 4593.6 6595.0 1928.4 821.6 1503.9 1512.6 1814.9 2939.2 2626.6 2651.7 163.2 17.2 3659.6 1310.2 3406.8 5015.0 360.5 4557.4 1983.9 3066.4 14.0 3997.3 1072.1 4293.5 16.1 23.3 2801.3 3326.6 2366.6 1803.5 5056.3 2925.9 3669.2 886.9 363.6 1709.2 3461.4 2748.7 674.8 779.0 2554.1 6196.5 4927.6 3651.6 2266.4 3979.8 5957.0 RPL3 L3 ENSG00000100316 "Ribosomal protein L3" P39023 22 39312882-39320389 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003365, HPA055361" Uncertain Supported Nucleoli,Cytosol NA NA 470000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli, Cytosol" "HPA003365: AB_1079841, HPA055361: AB_2732594" "unprognostic (9.79e-3)" "unprognostic (2.06e-1)" "unprognostic (2.31e-1)" "unprognostic (1.68e-3)" "unprognostic (5.44e-3)" "unprognostic (1.72e-1)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (3.63e-1)" "unprognostic (5.81e-2)" "unprognostic (5.87e-2)" "unprognostic (7.09e-2)" "unprognostic (2.54e-2)" "unprognostic (1.85e-1)" "unprognostic (6.09e-2)" "unprognostic (2.72e-1)" "unprognostic (4.32e-2)" 2058.6 1934.3 965.6 1484.2 985.8 2965.1 2704.2 936.9 1071.1 2705.4 1023.2 2078.1 1515.1 2007.3 1653.7 2522.3 2423.9 1128.4 1326.4 894.6 951.2 1745.2 1894.1 1421.2 2460.9 984.1 951.1 4838.0 4514.8 1462.2 1861.5 1099.8 977.1 2180.0 1361.7 809.1 2210.1 1551.8 558.4 3337.9 1722.9 1388.1 1050.0 1824.1 1982.0 752.6 1002.9 2006.1 1709.0 417.1 2320.5 2012.9 2317.5 996.1 2010.5 1836.9 2035.9 2149.6 2535.3 5394.1 2745.1 1497.8 2703.5 1400.5 1249.7 2327.8 1425.1 8262.2 2062.9 1734.1 873.2 1246.8 2275.3 3060.5 923.2 1448.3 2207.4 2039.5 2153.8 3438.2 3887.7 2932.6 1619.9 5321.2 4063.7 1265.0 4504.5 3956.7 2765.5 2217.6 2407.8 2657.6 2135.0 2597.5 2974.5 4241.1 2054.6 2172.9 1273.8 2369.5 1924.0 4017.5 2609.2 2927.6 1823.4 2180.2 936.2 2925.4 5031.9 1242.2 2226.2 4761.3 2864.1 951.4 1534.4 1027.8 1788.2 2074.0 1741.6 3606.5 2111.3 2564.4 1093.9 638.7 1690.8 351.4 3488.7 1481.6 5383.7 5629.1 4993.5 4037.9 2821.8 5113.1 6376.7 5111.7 215.7 4472.3 1339.8 3182.6 3668.7 11623.3 965.6 985.8 936.9 1071.1 894.6 951.2 984.1 951.1 977.1 1050.0 1002.9 996.1 2118.4 984.0 2299.9 16.3 4551.5 10412.0 9836.0 9475.4 2792.1 1065.7 9967.6 10172.3 182.6 4213.6 3849.3 1441.9 425.4 5623.9 4123.0 1288.7 5893.0 2943.4 2097.6 1061.7 2644.4 3666.1 2726.6 2263.9 17.0 6539.7 7508.2 2678.8 1207.4 1390.0 1784.7 4203.6 3429.3 2085.8 3282.5 358.4 18.3 3696.8 2925.6 3062.8 6215.2 4622.8 5581.1 2203.8 5104.8 17.8 3733.3 2455.8 4243.1 9.5 25.1 3814.3 2946.3 3499.2 2308.1 8261.9 3481.6 5422.4 1350.6 1305.5 1577.7 4469.5 4329.1 1074.6 1014.8 3712.4 12290.3 5489.4 4201.1 4673.7 4830.3 9407.7 RPLP0 "L10E, LP0, P0, PRLP0, RPP0" ENSG00000089157 "Ribosomal protein lateral stalk subunit P0" P05388 12 120196699-120201235 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003512, HPA073501" Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA 770000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA003512: AB_1079844, HPA073501: " "unprognostic (2.39e-3)" "unprognostic (2.46e-1)" "unprognostic (1.78e-1)" "unprognostic (8.49e-3)" "unprognostic (2.99e-2)" "unprognostic (2.44e-1)" "unprognostic (2.54e-3)" "unprognostic (5.99e-2)" "unprognostic (1.67e-1)" "unprognostic (4.82e-2)" "unprognostic (2.34e-1)" "unprognostic (3.35e-1)" "prognostic unfavorable (7.66e-12)" "unprognostic (2.74e-1)" "unprognostic (2.39e-1)" "unprognostic (3.06e-1)" "unprognostic (1.47e-1)" 1626.2 1344.7 561.3 1155.2 565.6 3283.8 2720.3 554.1 640.3 1534.6 616.4 1752.1 1554.5 1257.0 987.6 2694.1 2220.6 979.7 1047.9 552.7 585.8 878.9 1433.5 1081.9 1835.1 618.4 571.6 2860.3 3265.5 696.8 753.7 1202.7 602.2 1195.7 1776.6 523.0 1791.6 848.6 2407.5 2585.8 1260.0 1337.9 603.4 1135.2 1608.7 396.8 599.5 1835.9 1154.9 1590.0 2433.7 1778.7 1703.7 603.6 3354.4 3355.3 2339.0 4061.4 4653.6 7635.7 3627.8 2397.9 4274.8 3734.5 2395.4 4364.8 1919.1 7137.6 2541.5 4307.9 945.2 2583.2 4120.3 5060.1 2324.4 2764.8 3209.4 3343.3 2263.6 4630.2 5153.3 4498.4 2490.2 6817.1 8686.1 2619.4 8018.0 6670.0 4528.8 4037.2 4292.7 2014.6 3645.7 5140.3 4443.4 5661.6 4494.0 3290.9 3704.7 3321.6 3175.0 5868.8 3881.1 5170.2 2606.2 3183.0 1722.7 2593.0 5541.7 2631.2 4773.6 6518.2 3016.5 1807.3 2718.5 2322.7 3249.7 4551.6 5143.0 3549.4 3136.7 3560.7 1492.7 337.6 1714.3 136.4 1750.8 1555.9 3999.6 3712.1 3171.7 2361.5 3455.6 3456.2 3255.0 2728.7 123.0 2340.3 927.0 3805.3 2342.6 7075.7 561.3 565.6 554.1 640.3 552.7 585.8 618.4 571.6 602.2 603.4 599.5 603.6 594.8 586.5 1363.0 12.7 2571.7 3876.3 4947.2 3409.7 5507.4 208.7 3351.1 3986.1 277.8 1312.6 1946.7 562.8 154.3 4464.2 1352.3 967.9 1886.1 2150.7 448.8 811.6 1878.9 1354.0 1217.3 2826.9 12.8 4812.2 7058.4 1577.5 1782.3 1217.8 796.8 1334.4 963.1 1249.9 2014.1 94.2 19.7 2395.8 950.1 1281.9 2122.5 944.5 1740.7 1327.5 1700.4 17.8 1794.6 366.3 1030.9 19.6 28.6 2966.5 1712.5 795.1 4088.9 4142.9 1870.9 2089.5 859.3 486.4 420.7 1701.5 3223.9 309.4 759.2 7221.2 4751.9 4413.0 1892.0 2405.0 3317.6 5180.7 RPLP1 LP1 ENSG00000137818 "Ribosomal protein lateral stalk subunit P1" P05386 15 69452814-69456205 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 28402.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003368 Supported "Endoplasmic reticulum,Cytosol" NA NA 2000000 "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA003368: AB_1079845" "unprognostic (5.04e-3)" "unprognostic (2.26e-2)" "unprognostic (2.02e-2)" "unprognostic (4.29e-2)" "unprognostic (6.32e-2)" "unprognostic (1.35e-1)" "unprognostic (4.36e-2)" "unprognostic (2.92e-1)" "unprognostic (1.30e-1)" "unprognostic (2.36e-1)" "unprognostic (2.79e-1)" "unprognostic (9.55e-2)" "prognostic unfavorable (2.30e-9)" "unprognostic (7.75e-2)" "unprognostic (1.57e-1)" "unprognostic (2.59e-1)" "unprognostic (5.83e-2)" 1779.5 1664.6 852.0 893.4 872.7 2781.2 1895.2 821.7 1109.7 2465.3 920.5 2035.4 1200.3 1805.3 349.4 2773.4 1670.9 579.0 2121.7 813.6 844.4 1703.1 1566.2 1439.7 1583.3 871.6 857.5 3354.5 2003.6 264.6 924.6 565.5 866.0 1991.6 449.1 157.6 1705.8 417.0 4746.4 4498.6 1693.4 529.7 892.5 1992.0 2147.0 492.5 873.6 643.5 1140.9 761.4 1017.9 2099.9 2372.6 891.4 1890.5 1882.4 827.9 1919.4 1172.4 1394.2 1770.4 1615.7 960.9 892.0 711.8 1918.7 1861.9 2622.2 2346.4 869.5 811.2 2521.6 1296.6 1287.5 193.1 2639.9 3956.6 2208.5 2153.1 1914.5 2045.2 1976.4 1931.2 1782.1 2199.9 653.6 1219.6 1438.9 1092.7 2265.9 2127.7 2160.7 642.2 1757.0 2163.4 5781.3 3098.7 1172.2 1802.9 2192.5 2696.6 3893.7 876.0 2002.9 1319.3 2558.5 1620.5 1978.2 6979.8 742.8 1633.9 4449.5 1915.7 1273.2 2851.6 1535.0 2672.3 4382.2 7690.0 2245.6 1524.1 4968.6 1076.9 2903.3 5350.5 1819.3 3182.4 3677.4 5811.2 9096.0 6532.4 4349.4 6100.6 7551.7 6871.8 6057.1 733.9 5147.0 2138.6 6392.6 5921.8 13416.9 852.0 872.7 821.7 1109.7 813.6 844.4 871.6 857.5 866.0 892.5 873.6 891.4 3508.0 1891.0 3795.4 16.0 11229.3 24186.3 18565.6 9896.5 18630.1 626.6 14197.1 19613.8 1854.3 3877.6 5293.4 2265.9 350.3 9217.3 6668.2 2484.5 5141.7 5608.7 475.1 2702.4 5765.4 5131.7 2926.5 6423.8 19.7 7158.4 12076.7 5235.1 3541.4 4232.4 2605.7 4287.7 5261.2 6536.1 8166.9 373.5 22.5 7238.9 2396.6 8309.7 12226.0 1764.3 8447.2 6779.7 9051.8 28.1 11829.2 4015.4 6451.2 15.6 42.8 7495.3 5127.5 4732.9 10308.0 16198.4 5565.3 8039.9 2204.8 1167.3 2530.9 5356.8 5872.6 690.3 1864.1 18779.3 28402.5 9502.3 9179.6 6940.6 8549.1 17342.5 RPLP2 "D11S2243E, LP2, MGC71408, P2, RPP2" ENSG00000177600 "Ribosomal protein lateral stalk subunit P2" P05387 11 809965-812880 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053635, HPA075365" Approved Approved "Nuclear speckles,Mitotic spindle,Cytosol" "Intracellular and membrane" Yes NA 2900000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" "Nuclear speckles, Cytosol" "Mitotic spindle" "HPA053635: AB_2682212, HPA075365: " "unprognostic (6.98e-3)" "unprognostic (2.21e-1)" "unprognostic (4.57e-2)" "unprognostic (8.63e-2)" "unprognostic (2.30e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (1.63e-1)" "unprognostic (2.98e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (2.19e-6)" "unprognostic (6.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.16e-1)" "unprognostic (3.31e-2)" 2013.7 831.3 1119.2 993.1 1162.5 2166.9 1656.6 1099.7 1368.9 1256.2 1084.1 1277.1 1016.8 930.2 701.6 1241.3 1240.4 564.0 869.3 1057.5 1116.3 885.0 657.0 851.0 1924.7 1138.0 1095.8 2092.8 2087.8 545.7 595.5 830.9 1154.3 925.8 887.8 180.9 1908.3 775.7 1802.7 1760.4 1191.7 624.4 1204.8 1543.8 1006.0 377.6 1167.5 1545.7 785.0 936.1 1715.4 1075.5 1137.9 1217.7 2773.5 2229.6 1070.4 1864.1 2343.2 2458.2 2389.5 1728.2 1285.0 2090.8 1638.4 3307.6 2218.5 3851.6 1225.0 1629.9 1107.9 2546.7 1786.2 2778.3 836.3 1713.6 8117.9 1901.7 1416.9 3996.4 2837.3 3540.8 1905.4 3393.9 4684.6 764.1 2182.7 1860.8 2111.9 2798.2 3432.2 2040.5 1317.9 2656.6 2969.5 6002.3 3188.8 3394.5 6045.3 3345.1 1465.6 4369.9 1759.0 1281.0 2222.2 3142.1 1118.5 2825.8 3582.4 885.1 1198.9 3577.2 1881.2 1142.3 1393.9 964.1 1981.6 3838.4 3778.8 3419.3 1790.5 2952.3 1340.6 1565.3 3908.1 1299.1 4402.2 3129.1 6208.3 10718.3 8296.0 6323.4 4273.6 9867.1 10158.6 8083.9 529.9 4310.4 2525.7 5882.9 5140.5 13330.7 1119.2 1162.5 1099.7 1368.9 1057.5 1116.3 1138.0 1095.8 1154.3 1204.8 1167.5 1217.7 1311.8 1067.3 1685.0 16.3 5889.9 6113.3 6658.4 2808.0 2619.1 206.2 5955.7 4736.9 638.4 2505.0 1972.2 1601.9 79.2 5046.4 3469.2 2296.4 2592.4 3688.3 1403.0 1105.9 2434.1 2724.8 2370.2 3482.2 18.6 7413.9 8045.8 2074.3 1401.2 1787.6 1721.9 1543.2 4028.6 3068.9 4514.0 146.4 17.8 5925.5 870.8 5458.4 6404.8 3133.4 6393.4 3169.4 2986.4 27.2 5854.8 1052.2 5787.9 6.0 19.0 5201.1 4547.7 2821.7 2403.4 6640.3 4473.8 4234.1 900.4 235.5 1991.9 3688.9 2346.3 1123.1 2093.1 4264.4 7887.4 5841.1 4889.3 1629.7 6189.1 7014.0 RPN2 "RIBIIR, RPN-II, RPNII, SWP1" ENSG00000118705 "Ribophorin II" P04844 20 37178410-37241619 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 599.6;Syncytiotrophoblasts: 621.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008297, CAB019277, HPA025922" Enhanced Supported "Endoplasmic reticulum" NA NA 1300000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB019277: , HPA008297: AB_1856457, HPA025922: AB_1856458" "unprognostic (9.59e-3)" "unprognostic (5.22e-2)" "unprognostic (1.66e-2)" "unprognostic (1.06e-1)" "unprognostic (1.99e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.82e-2)" "unprognostic (1.09e-1)" "unprognostic (2.58e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "prognostic unfavorable (1.44e-10)" "unprognostic (2.83e-1)" "unprognostic (6.99e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (2.44e-4)" 112.6 132.5 48.2 131.9 50.4 180.8 146.1 49.9 55.9 161.8 98.0 156.9 125.5 108.7 344.1 106.8 122.9 119.8 107.3 49.5 56.5 145.1 212.1 129.7 109.2 54.0 50.6 94.8 159.6 180.9 79.1 257.9 53.9 164.4 175.2 117.0 158.2 157.5 110.4 91.5 110.9 156.6 53.8 118.1 145.1 144.2 55.4 108.5 232.5 75.1 143.3 165.4 87.9 61.9 328.2 290.6 302.7 401.2 413.1 308.2 586.7 426.7 516.8 544.8 459.2 939.2 564.8 255.3 501.6 572.3 506.4 468.4 318.8 516.4 492.0 121.2 196.5 295.3 308.4 634.1 398.9 468.4 467.0 294.6 505.1 432.3 447.5 519.8 530.4 239.2 458.7 805.1 389.1 300.9 270.6 451.0 240.4 839.3 415.7 242.3 549.1 852.7 371.6 304.3 246.4 261.0 517.9 1231.1 489.4 353.6 606.1 765.6 338.0 600.8 358.2 317.1 371.9 474.7 608.4 259.9 583.4 314.9 493.2 424.2 427.5 285.5 365.5 410.5 417.0 291.0 336.1 363.8 481.2 232.4 298.8 308.7 78.3 398.8 357.6 591.0 338.2 676.5 48.2 50.4 49.9 55.9 49.5 56.5 54.0 50.6 53.9 53.8 55.4 61.9 85.7 118.6 158.0 22.2 107.8 61.8 134.1 264.6 62.0 72.6 90.0 74.2 81.4 133.0 197.7 80.9 45.9 461.6 109.6 113.9 23.5 278.0 37.3 73.2 103.5 98.6 63.0 91.7 18.8 241.1 599.6 127.4 84.1 151.2 105.2 109.3 100.6 206.3 233.2 63.9 18.6 168.5 162.8 150.4 75.3 24.4 105.0 117.0 90.7 20.6 122.2 136.8 65.9 24.1 20.5 160.1 109.5 110.9 392.3 121.3 64.6 82.3 98.5 100.8 85.5 65.3 122.0 335.2 288.9 67.7 57.8 621.0 81.5 213.7 138.7 117.6 RPRD2 "FLJ32145, HSPC099, KIAA0460" ENSG00000163125 "Regulation of nuclear pre-mRNA domain containing 2" Q5VT52 1 150363091-150476566 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 132.9;Inhibitory neurons: 133.8;Oligodendrocyte precursor cells: 136.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061693 Approved Approved Nucleoplasm,Vesicles NA NA 66000 "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "HPA061693: AB_2684587" "unprognostic (1.68e-1)" "unprognostic (1.52e-1)" "unprognostic (2.00e-1)" "unprognostic (7.25e-2)" "unprognostic (5.67e-3)" "unprognostic (3.79e-2)" "unprognostic (1.75e-2)" "unprognostic (9.03e-2)" "unprognostic (1.50e-1)" "unprognostic (3.93e-2)" "unprognostic (2.52e-1)" "unprognostic (1.27e-1)" "unprognostic (1.10e-3)" "unprognostic (1.11e-1)" "unprognostic (1.71e-1)" "unprognostic (7.92e-2)" "unprognostic (1.38e-1)" 10.8 11.4 6.1 10.8 7.4 13.7 12.0 17.4 11.0 16.0 3.2 13.2 10.6 18.9 14.2 14.0 21.1 10.7 13.2 7.3 8.1 16.0 11.4 12.9 13.6 4.2 5.3 29.8 14.5 19.2 10.7 9.8 4.3 14.3 14.5 17.4 14.0 16.2 24.5 12.8 12.1 17.8 3.8 14.0 11.9 14.1 7.7 19.5 23.0 22.8 15.7 12.7 11.3 7.9 24.6 18.4 23.9 24.3 24.3 20.5 22.6 17.4 20.7 18.8 18.4 16.1 29.4 38.8 19.5 21.4 10.4 26.6 34.0 25.9 20.4 17.9 14.2 22.3 21.2 19.5 17.4 33.8 26.3 21.8 19.3 26.2 34.4 20.9 23.5 23.2 22.1 40.9 19.3 35.4 29.8 10.9 30.0 30.9 20.6 27.0 17.7 39.4 27.7 22.4 25.4 25.6 35.6 30.0 22.6 21.2 23.7 29.5 21.7 17.3 17.8 14.6 24.9 24.9 29.5 28.7 17.2 24.8 17.4 5.8 2.9 3.5 5.6 1.8 5.1 5.4 5.3 4.5 2.6 5.2 6.1 6.2 1.4 3.9 7.3 3.1 7.0 2.4 6.1 7.4 17.4 11.0 7.3 8.1 4.2 5.3 4.3 3.8 7.7 7.9 18.7 19.2 25.9 97.3 30.8 15.4 10.5 17.1 25.0 35.0 22.0 19.8 27.6 17.2 24.5 33.1 16.7 14.0 27.2 20.6 7.9 14.6 11.0 31.8 30.1 21.6 25.8 16.8 132.9 12.9 9.1 23.4 16.8 33.5 17.7 28.5 26.0 27.1 14.7 11.8 133.8 22.1 18.3 22.6 10.5 6.6 37.9 16.6 10.6 56.2 18.6 22.9 27.8 136.2 112.2 14.1 17.7 39.9 29.6 16.4 21.6 30.8 29.9 29.8 32.9 37.1 20.6 21.1 21.3 26.4 14.6 10.0 27.6 27.3 22.3 16.9 RPS27L ENSG00000185088 "Ribosomal protein S27 like" Q71UM5 15 63125872-63158021 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 2535.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA066851 Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA066851: AB_2685737" "unprognostic (4.62e-2)" "unprognostic (5.81e-2)" "unprognostic (1.38e-1)" "prognostic favorable (9.08e-6)" "unprognostic (1.75e-1)" "unprognostic (7.24e-2)" "unprognostic (1.42e-3)" "unprognostic (2.98e-1)" "unprognostic (6.38e-2)" "unprognostic (1.80e-1)" "unprognostic (2.19e-3)" "unprognostic (2.51e-1)" "unprognostic (1.97e-2)" "unprognostic (5.31e-2)" "unprognostic (1.36e-1)" "unprognostic (1.97e-3)" "unprognostic (5.10e-3)" 142.2 242.4 78.6 71.3 80.6 73.2 127.1 81.5 113.1 124.7 102.5 190.8 157.4 108.4 157.9 70.8 117.9 94.8 181.0 78.1 84.2 194.5 266.0 109.4 83.5 82.9 81.7 95.9 247.4 94.0 88.6 69.3 84.5 156.2 178.0 31.8 164.7 106.7 190.1 75.9 161.4 80.7 86.0 103.2 174.7 38.1 81.4 86.3 106.5 97.7 68.2 149.2 94.1 90.0 140.4 383.0 340.4 92.9 486.4 571.3 341.3 432.1 306.0 93.8 225.3 71.1 190.0 130.8 150.9 415.9 166.0 52.9 116.5 212.9 155.7 97.8 157.5 108.3 329.1 512.7 558.7 86.8 287.0 452.1 279.0 211.2 158.4 701.2 535.2 81.2 101.6 127.7 785.1 194.1 112.4 134.9 101.0 178.0 112.6 86.9 163.1 149.5 266.7 278.8 49.2 74.7 157.6 65.8 326.2 677.8 145.4 199.1 571.1 490.6 463.8 106.7 195.3 142.3 132.3 117.5 518.5 235.6 453.8 263.8 132.5 164.6 99.4 145.2 125.2 132.0 149.9 118.1 122.0 105.2 116.9 119.4 44.3 110.9 198.2 121.3 305.2 166.0 78.6 80.6 81.5 113.1 78.1 84.2 82.9 81.7 84.5 86.0 81.4 90.0 210.9 96.1 198.6 9.4 255.9 255.4 262.6 424.8 230.5 33.4 361.3 429.1 349.0 511.9 424.6 410.1 47.9 300.1 144.9 694.7 903.9 802.7 60.9 202.3 185.3 245.8 285.4 184.5 12.6 782.4 1269.2 269.2 327.8 155.5 302.6 250.8 302.0 994.8 542.1 13.5 15.6 742.3 520.8 372.1 358.1 34.4 314.7 270.3 466.0 17.8 1049.6 184.8 221.4 16.1 18.5 1019.3 745.5 297.5 495.5 324.6 1513.1 2535.3 330.9 75.2 263.0 180.5 742.6 144.7 82.1 183.6 247.6 235.2 224.7 214.3 732.5 215.2 RPS6KC1 "humS6PKh1, RSKL1" ENSG00000136643 "Ribosomal protein S6 kinase C1" Q96S38 1 213051233-213274774 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 86.2;Excitatory neurons: 273.2;Inhibitory neurons: 151.2;Microglial cells: 101.2;Oligodendrocyte precursor cells: 116.6;Oligodendrocytes: 137.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 16.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026531, HPA031565" Approved Supported Endosomes,Lysosomes NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 78: Testis - Spermatogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endosomes, Lysosomes" "HPA026531: AB_10601497, HPA031565: AB_2673935" "unprognostic (3.90e-2)" "unprognostic (5.90e-2)" "unprognostic (3.22e-1)" "unprognostic (4.88e-2)" "unprognostic (2.42e-1)" "unprognostic (9.81e-2)" "unprognostic (1.32e-2)" "unprognostic (1.64e-1)" "unprognostic (4.10e-2)" "unprognostic (3.34e-1)" "unprognostic (4.18e-1)" "unprognostic (5.11e-2)" "prognostic unfavorable (2.70e-4)" "unprognostic (8.10e-2)" "unprognostic (5.48e-2)" "unprognostic (2.98e-2)" "unprognostic (4.44e-2)" 8.3 8.8 9.7 7.1 11.5 4.9 7.2 8.2 13.9 8.8 4.3 7.8 6.2 9.4 5.2 6.7 7.6 7.7 6.4 12.9 8.8 6.4 7.4 7.1 5.2 8.6 8.8 9.2 9.2 10.2 4.5 8.4 8.6 11.5 6.5 9.3 6.8 11.3 10.0 4.3 6.0 12.6 8.6 7.9 8.6 19.3 9.9 5.4 6.9 11.6 5.4 8.1 4.6 13.2 11.0 9.3 15.0 16.3 15.0 21.6 13.2 14.1 20.7 21.5 24.6 7.7 11.9 6.9 9.3 21.4 14.1 8.9 18.3 11.6 16.2 14.7 6.7 18.7 10.9 10.5 13.6 11.9 21.4 14.3 9.8 18.8 10.2 17.9 18.2 6.7 24.6 10.5 22.3 6.3 5.0 3.9 21.8 9.8 10.4 5.9 14.1 6.8 9.7 10.9 8.7 22.6 15.3 11.9 20.6 25.5 17.1 4.9 17.0 14.6 13.3 16.9 9.3 6.1 12.6 5.2 6.2 4.5 15.2 16.8 4.5 3.5 2.5 6.4 2.1 2.4 2.0 2.2 8.5 1.6 1.3 3.0 0.5 3.8 6.7 1.0 1.6 2.2 9.7 11.5 8.2 13.9 12.9 8.8 8.6 8.8 8.6 8.6 9.9 13.2 10.1 9.6 5.8 86.2 8.8 2.9 2.7 4.5 7.4 17.4 6.6 5.6 9.6 7.2 4.3 0.0 14.6 3.5 7.7 4.8 0.0 5.2 33.6 7.4 12.1 9.9 3.6 12.4 273.2 8.0 4.0 10.1 15.3 9.9 7.6 16.6 7.9 9.3 7.1 20.2 151.2 3.3 6.1 11.4 7.7 45.2 11.1 15.1 7.2 101.2 13.1 5.6 10.3 116.6 137.6 6.6 2.1 7.5 8.1 5.4 4.4 5.7 4.7 20.0 13.1 13.7 9.1 19.6 19.6 9.1 4.4 3.8 10.4 6.1 4.3 3.2 RPUSD4 FLJ14494 ENSG00000165526 "RNA pseudouridine synthase D4" Q96CM3 11 126202096-126211692 "Metabolic proteins, Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 135.5;tongue: 75.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039689 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Nucleoplasm "HPA039689: AB_10673537" "unprognostic (2.02e-2)" "unprognostic (3.65e-1)" "prognostic favorable (6.14e-4)" "unprognostic (3.16e-3)" "unprognostic (2.90e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.32e-1)" "unprognostic (7.64e-3)" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (1.20e-2)" "unprognostic (1.56e-1)" "unprognostic (7.11e-2)" "unprognostic (5.44e-2)" "unprognostic (7.33e-2)" "unprognostic (5.47e-2)" 14.8 12.7 10.2 9.8 10.4 10.6 14.0 10.5 11.2 13.8 10.7 12.1 10.4 12.6 7.7 15.1 12.9 8.1 27.2 10.5 10.4 11.8 20.5 9.4 13.8 10.2 10.2 18.3 26.8 7.8 8.8 6.8 10.5 11.5 10.1 6.1 14.4 7.0 135.5 17.1 12.1 9.2 10.6 14.4 20.0 8.8 10.5 13.2 10.1 75.2 15.5 12.4 13.4 10.5 15.6 14.0 17.0 19.7 24.5 34.3 12.5 16.2 22.7 16.6 15.1 46.4 27.3 35.7 16.8 14.1 23.7 25.1 40.3 25.8 17.3 32.4 23.9 84.1 15.0 40.5 18.3 42.5 17.1 29.8 35.0 18.4 22.9 24.8 33.4 28.8 51.8 25.1 20.2 13.5 26.6 46.3 18.4 49.3 29.1 31.0 25.2 33.3 25.7 19.8 29.3 20.5 21.5 29.7 16.7 17.0 46.2 21.9 20.9 18.6 13.3 15.4 19.9 10.1 12.4 30.7 8.8 47.2 19.7 1.6 12.7 1.4 15.9 11.7 19.6 14.4 18.0 14.3 16.3 14.5 20.4 16.8 0.9 14.3 14.0 7.0 18.1 13.3 10.2 10.4 10.5 11.2 10.5 10.4 10.2 10.2 10.5 10.6 10.5 10.5 10.0 3.2 8.4 6.8 15.3 27.5 20.4 13.2 17.1 9.9 13.1 9.1 35.4 12.8 7.4 7.3 8.4 14.0 12.3 7.2 9.8 12.3 1.8 6.7 7.1 11.9 15.5 6.7 7.0 19.6 17.1 10.2 10.7 7.4 5.7 15.2 13.6 11.3 13.3 11.8 8.4 10.7 2.0 15.9 8.7 2.3 9.6 8.6 10.6 8.4 21.0 5.3 14.4 6.6 7.8 13.5 7.4 8.6 12.4 17.4 15.6 14.5 7.0 8.2 6.6 15.6 9.9 10.3 16.7 13.2 24.0 13.3 13.1 18.3 18.8 14.7 RRBP1 "ES/130, hES" ENSG00000125844 "Ribosome binding protein 1" Q9P2E9 20 17613678-17682295 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 497.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 588.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.8;plasmacytoid DC: 44.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009026, HPA011924" Enhanced Enhanced "Endoplasmic reticulum" NA NA 320000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "HPA009026: AB_1079852, HPA011924: AB_1856476" "unprognostic (1.56e-3)" "unprognostic (2.26e-3)" "unprognostic (8.46e-2)" "prognostic favorable (1.41e-4)" "unprognostic (1.04e-1)" "unprognostic (1.05e-1)" "unprognostic (2.92e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (6.89e-2)" "unprognostic (3.03e-1)" "unprognostic (5.09e-2)" "unprognostic (6.63e-2)" "unprognostic (9.21e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.38e-4)" 64.2 72.3 27.0 62.8 41.9 28.1 54.6 41.1 32.2 69.1 52.3 98.3 76.1 59.5 55.0 67.8 45.1 71.5 59.1 27.5 35.3 77.4 219.0 80.2 28.2 49.3 42.2 48.3 497.7 72.4 63.4 107.9 45.5 66.5 65.9 17.7 228.2 63.4 21.9 43.6 82.7 46.0 37.7 57.7 123.1 48.4 40.9 14.4 130.4 14.7 27.0 57.6 55.2 49.2 173.5 121.0 35.7 80.4 160.3 172.2 186.2 264.3 221.3 110.0 148.2 271.2 159.3 66.5 87.3 252.2 113.4 170.4 38.7 215.4 89.1 30.9 29.7 76.2 34.9 283.6 229.4 29.0 93.0 228.9 63.8 178.7 104.3 161.7 109.7 23.4 32.6 62.9 167.6 78.8 11.4 65.5 41.6 383.3 115.8 20.1 94.2 231.3 93.0 58.4 18.2 13.7 151.1 353.2 108.4 75.0 62.0 43.5 198.7 232.7 85.9 122.1 88.5 114.6 93.6 21.6 88.1 30.7 121.1 11.7 8.4 37.8 4.3 5.5 3.2 1.0 1.4 2.6 4.6 1.4 1.4 1.6 7.8 10.7 8.4 44.4 1.5 3.1 27.0 41.9 41.1 32.2 27.5 35.3 49.3 42.2 45.5 37.7 40.9 49.2 146.8 96.1 197.1 15.0 72.5 59.1 92.3 90.3 55.2 21.9 127.0 76.3 46.4 144.4 158.2 95.6 31.3 262.0 180.6 588.9 45.0 199.7 47.2 117.5 228.4 155.8 97.0 31.6 3.0 414.6 235.8 219.7 294.6 322.8 118.9 78.1 118.9 279.9 117.4 25.2 4.9 507.9 50.8 62.0 85.7 44.3 127.1 91.6 71.2 17.8 75.1 144.3 79.3 23.1 27.6 357.7 452.3 83.1 570.6 145.6 221.6 57.2 121.8 35.5 32.9 165.1 169.8 77.5 139.9 73.2 55.8 532.9 56.9 114.6 329.3 218.5 RS1 "RS, XLRS1" ENSG00000102104 "Retinoschisin 1" O15537 X 18639688-18672108 "Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 207 "retina: 213.7" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 160.6;Rod photoreceptor cells: 162.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059546 Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA059546: AB_2684058" "unprognostic (8.31e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (2.39e-2)" "unprognostic (1.86e-1)" "unprognostic (4.80e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-2)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "unprognostic (4.77e-3)" "unprognostic (4.14e-1)" "unprognostic (7.03e-2)" "unprognostic (1.06e-1)" "unprognostic (3.06e-2)" "unprognostic (5.12e-2)" "unprognostic (2.04e-4)" 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 213.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 6.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 15.3 0.0 0.0 1.9 0.0 0.0 0.0 160.6 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 162.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 RSBN1 "FLJ11220, ROSBIN" ENSG00000081019 "Round spermatid basic protein 1" Q5VWQ0 1 113761832-113812476 "Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042124, HPA049484" Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies, Vesicles" "HPA042124: AB_10794644, HPA049484: AB_2680787" "unprognostic (3.26e-2)" "unprognostic (1.32e-1)" "unprognostic (1.15e-3)" "unprognostic (2.13e-1)" "unprognostic (3.66e-2)" "unprognostic (2.30e-2)" "unprognostic (5.06e-2)" "unprognostic (6.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-2)" "unprognostic (1.56e-1)" "unprognostic (3.96e-1)" "unprognostic (1.51e-2)" "unprognostic (4.67e-2)" "unprognostic (1.43e-1)" "unprognostic (1.24e-1)" "unprognostic (1.15e-3)" 6.4 6.0 4.6 7.7 4.7 34.4 8.2 12.7 6.1 7.9 2.8 8.4 6.2 10.3 6.5 7.3 7.9 6.4 5.2 4.2 5.3 8.0 6.4 7.5 10.6 3.1 3.7 14.2 11.0 11.0 5.1 6.6 3.2 7.9 8.6 13.7 6.8 6.9 8.0 7.5 7.5 7.0 3.9 9.2 6.8 10.7 4.3 12.3 9.0 7.9 10.5 6.4 5.5 5.2 14.6 4.1 13.7 8.2 8.0 9.2 6.6 5.1 10.9 10.1 10.5 4.9 4.3 12.7 7.9 6.3 4.6 6.2 9.8 6.2 16.4 12.3 7.1 9.6 4.4 5.6 6.0 18.1 9.9 7.0 6.7 8.6 8.2 8.6 8.1 14.0 14.7 7.7 7.5 14.9 14.7 10.8 11.6 4.6 6.9 26.3 13.4 6.6 6.0 6.2 13.8 11.0 9.7 9.4 8.7 6.8 4.5 12.1 9.7 9.0 9.7 13.5 8.3 10.3 8.2 15.9 9.3 10.9 15.4 53.3 14.5 25.6 29.1 11.7 29.3 32.2 31.2 27.2 12.8 33.1 31.9 26.2 29.0 25.4 13.4 27.3 30.6 12.6 4.6 4.7 12.7 6.1 4.2 5.3 3.1 3.7 3.2 3.9 4.3 5.2 37.4 35.3 20.1 16.0 52.7 74.7 39.2 26.9 45.5 90.0 35.0 46.7 21.5 24.3 29.6 25.8 66.7 26.3 68.0 55.5 19.6 22.3 25.6 26.2 39.4 38.9 49.4 37.5 34.3 26.0 24.1 41.5 17.9 28.8 36.1 23.4 32.5 18.7 19.2 97.6 34.2 58.5 28.5 26.3 37.7 9.0 50.4 25.7 40.9 30.9 35.0 56.7 62.8 33.7 34.6 21.2 54.0 49.7 34.7 44.3 40.2 17.2 27.8 106.5 39.5 43.8 54.9 96.8 37.0 34.3 65.1 31.5 84.8 24.2 52.7 37.8 RSF1 "HBXAP, p325, RSF-1, XAP8" ENSG00000048649 "Remodeling and spacing factor 1" Q96T23 11 77659996-77821017 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022626, HPA046129, HPA057547, HPA064567" Supported Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "CAB022626: , HPA046129: AB_2679550, HPA057547: AB_2683462, HPA064567: AB_2685289" "unprognostic (2.67e-1)" "unprognostic (2.02e-1)" "unprognostic (2.39e-1)" "unprognostic (4.35e-3)" "unprognostic (5.00e-3)" "unprognostic (5.57e-2)" "unprognostic (1.23e-2)" "unprognostic (2.46e-1)" "unprognostic (7.33e-3)" "unprognostic (2.35e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (6.19e-2)" "prognostic favorable (5.94e-4)" "unprognostic (1.71e-1)" "unprognostic (2.22e-1)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" 12.5 17.9 10.8 16.5 12.9 25.7 15.4 43.9 13.7 17.1 1.5 12.8 9.4 20.0 8.9 14.1 14.5 16.6 14.0 8.7 15.4 14.3 11.7 13.2 15.3 8.3 8.5 26.3 16.9 17.3 6.5 18.5 8.5 15.4 12.6 25.9 10.2 13.4 11.7 9.3 10.8 17.5 8.0 16.3 13.5 23.8 12.0 22.6 22.3 13.4 13.5 17.0 8.4 15.5 27.7 18.2 62.0 33.3 20.6 25.9 23.3 31.7 31.0 25.5 31.4 48.0 37.5 46.7 33.2 22.3 39.4 28.1 36.8 23.8 47.7 33.4 16.3 43.9 25.1 13.0 19.6 42.2 30.0 21.8 17.5 35.0 55.8 29.7 32.7 15.2 72.8 43.0 29.7 18.7 29.7 23.4 36.1 32.9 24.8 49.1 107.5 30.6 13.5 35.5 37.3 37.6 48.8 19.1 18.5 32.2 34.3 20.6 41.2 45.0 38.8 71.0 23.1 25.7 35.7 106.3 11.9 28.1 34.5 49.3 17.8 32.8 27.4 16.9 18.8 34.3 16.6 17.6 14.2 35.0 22.7 22.9 46.4 23.7 30.1 32.0 17.0 7.5 10.8 12.9 43.9 13.7 8.7 15.4 8.3 8.5 8.5 8.0 12.0 15.5 100.3 118.6 113.5 99.6 98.0 90.5 69.3 89.7 93.9 123.0 68.8 85.1 97.1 54.3 84.3 73.5 75.0 57.8 85.1 53.0 46.9 79.2 112.4 72.9 95.2 96.5 85.6 71.8 129.4 55.3 50.6 90.5 51.0 86.0 95.5 132.5 79.9 46.2 45.6 146.4 129.3 64.7 71.2 62.9 68.5 40.3 126.8 66.5 56.9 98.4 93.9 124.6 120.5 157.8 144.7 73.1 63.4 118.1 74.8 97.6 44.1 38.2 69.7 97.6 105.2 99.3 100.4 114.8 109.4 57.2 84.0 67.5 99.9 141.7 58.1 91.6 RSPO1 "FLJ40906, RSPONDIN" ENSG00000169218 "R-spondin 1" Q2MKA7 1 37611350-37634892 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 28.9;endometrium 1: 41.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 7.7;Breast myoepithelial cells: 15.6;Fibroblasts: 5.4;Langerhans cells: 2.9" "Cancer enriched" "Detected in some" 13 "ovarian cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.2;THP-1: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046154, HPA062923" Uncertain Approved Vesicles "Secreted in female reproductive system" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA046154: AB_10964912, HPA062923: " "unprognostic (1.50e-2)" "unprognostic (1.97e-3)" "unprognostic (5.99e-3)" "unprognostic (2.22e-1)" "unprognostic (1.76e-1)" "unprognostic (3.75e-6)" "unprognostic (1.84e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (2.08e-1)" "unprognostic (1.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.76e-2)" "unprognostic (3.21e-1)" "unprognostic (1.53e-2)" 11.3 0.1 0.0 0.8 0.1 0.1 7.9 0.1 0.1 28.9 0.0 1.8 1.1 41.4 2.2 3.1 20.0 2.7 0.7 0.1 0.0 0.8 0.1 4.0 1.9 0.1 0.1 2.1 0.5 0.1 0.1 0.4 0.1 6.7 0.5 0.1 1.3 1.8 0.0 6.6 3.3 13.1 0.0 0.8 4.0 0.2 0.1 0.0 0.0 0.5 3.0 1.5 19.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 7.7 15.6 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.9 0.1 0.9 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.4 0.1 0.3 0.0 0.0 0.1 RSPO2 MGC35555 ENSG00000147655 "R-spondin 2" Q6UXX9 8 107899316-108083642 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" "Developmental protein, Heparin-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.0;intestine: 13.9;placenta: 17.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 75.3;Inhibitory neurons: 86.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.2;U-266/70: 4.2" "Group enriched" "Detected in many" 7 "amygdala: 7.9;cerebral cortex: 17.9;hippocampal formation: 21.3;white matter: 13.2" "Group enriched" "Detected in many" 4 "amygdala: 8.3;cerebral cortex: 7.7;hippocampal formation: 8.5;midbrain: 12.9;spinal cord: 7.7" "HPA024764, CAB025900, HPA053068" Uncertain "Secreted in other tissues" NA NA "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB025900: , HPA024764: AB_10603236, HPA053068: AB_2682031" "unprognostic (1.10e-2)" "unprognostic (2.18e-1)" "unprognostic (3.97e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.19e-1)" "unprognostic (8.33e-3)" "unprognostic (1.82e-1)" "unprognostic (9.48e-2)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (8.45e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" 0.2 0.0 2.8 0.7 4.4 0.1 0.0 1.3 16.2 3.4 2.6 13.9 3.4 0.0 1.7 5.9 0.0 3.2 0.2 6.6 13.2 0.0 0.4 7.1 0.0 2.6 23.0 0.3 0.0 0.0 2.9 17.3 2.0 8.7 7.8 0.3 0.0 2.3 0.0 0.0 4.6 0.3 2.1 0.0 7.6 0.7 3.5 0.0 0.0 0.0 0.0 1.7 0.8 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.4 1.3 16.2 6.6 13.2 2.6 23.0 2.0 2.1 3.5 6.6 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 75.3 0.0 0.3 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 86.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 4.7 0.0 0.0 0.0 4.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.6 0.0 1.7 0.0 0.0 1.0 0.0 0.2 0.0 0.0 RSPO3 "FLJ14440, THSD2" ENSG00000146374 "R-spondin 3" Q9BXY4 6 127118671-127199481 "Cancer-related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 51.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 18.5;Endothelial cells: 42.4;Fibroblasts: 73.0;Hepatic stellate cells: 26.4;Inhibitory neurons: 17.8;Leydig cells: 27.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 21.9;BJ hTERT+: 3.6;hTERT-RPE1: 6.3;U-138 MG: 4.6;U-87 MG: 4.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 21.2" HPA029957 Uncertain "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 33: Fibroblasts - ECM organization" "HPA029957: AB_10602087" "unprognostic (4.77e-2)" "unprognostic (3.95e-2)" "unprognostic (1.27e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-1)" "unprognostic (2.99e-1)" "unprognostic (9.71e-2)" "unprognostic (1.49e-2)" "unprognostic (3.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-1)" "unprognostic (1.07e-3)" "unprognostic (7.94e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-2)" "unprognostic (7.89e-3)" 30.9 15.1 2.1 16.1 2.4 0.0 12.4 3.3 4.9 13.8 0.0 7.4 2.2 51.4 28.4 5.4 25.3 11.1 0.9 8.5 1.5 4.0 6.5 5.1 3.7 1.6 1.4 3.6 1.6 0.1 3.1 35.4 0.3 6.3 6.6 0.1 5.4 20.0 39.8 2.8 10.3 48.1 0.0 1.8 13.3 1.0 1.0 2.4 3.6 5.0 1.4 8.6 7.1 0.9 0.0 21.9 0.0 0.0 1.0 0.0 0.0 0.0 3.6 0.3 0.4 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 6.3 2.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 4.6 1.8 0.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 3.3 4.9 8.5 1.5 1.6 1.4 0.3 0.0 1.0 0.9 3.6 0.0 0.0 0.7 0.1 0.9 0.1 0.0 0.6 1.5 0.2 0.9 0.5 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.4 12.3 0.3 18.5 42.4 0.0 0.0 5.9 0.0 1.1 73.0 5.1 0.3 0.0 0.0 26.4 0.4 1.6 0.0 17.8 0.0 0.0 1.0 0.8 2.2 27.4 0.4 1.8 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.2 6.6 2.1 3.5 0.1 0.4 0.4 0.1 1.6 0.1 0.1 0.0 0.2 RSPO4 "C20orf182, dJ824F16.3" ENSG00000101282 "R-spondin 4" Q2I0M5 20 958452-1002311 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.0;lung: 12.6" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Early spermatids: 6.6;Late spermatids: 7.3;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.0;EFO-21: 2.0;fHDF/TERT166: 2.4;NTERA-2: 6.3;SK-BR-3: 4.3;U-2 OS: 6.9" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" HPA048887 Uncertain "Secreted in other tissues" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "HPA048887: AB_2680545" "unprognostic (2.36e-1)" "unprognostic (3.60e-3)" "unprognostic (2.88e-2)" "prognostic unfavorable (2.98e-6)" "unprognostic (8.93e-2)" "unprognostic (1.14e-3)" "unprognostic (1.05e-2)" "unprognostic (1.47e-1)" "unprognostic (6.50e-2)" "unprognostic (2.02e-2)" "unprognostic (5.26e-3)" "unprognostic (2.96e-1)" "unprognostic (5.68e-9)" "unprognostic (6.65e-3)" "unprognostic (4.41e-2)" "unprognostic (6.18e-3)" "unprognostic (2.22e-2)" 0.3 0.2 4.3 0.6 4.6 0.0 1.3 2.1 6.7 0.6 1.1 0.3 0.1 0.3 1.4 0.8 1.6 0.4 0.5 3.4 7.6 0.6 0.3 12.6 0.0 13.0 8.4 0.4 0.3 0.3 2.1 0.2 12.6 0.4 0.0 1.2 0.4 0.2 0.1 3.0 0.3 0.0 3.8 0.2 0.2 3.2 9.6 0.0 3.0 0.0 0.4 0.2 0.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.2 0.0 0.1 0.0 0.0 0.0 0.8 2.0 2.4 0.3 0.0 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 4.3 0.0 0.0 0.1 0.0 0.0 0.0 6.9 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 4.6 2.1 6.7 3.4 7.6 13.0 8.4 12.6 3.8 9.6 2.2 0.0 0.0 0.0 10.7 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 6.6 0.1 0.0 0.3 0.0 0.0 2.9 0.0 0.6 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.8 7.3 0.0 0.0 1.8 1.9 0.0 0.1 0.0 8.5 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 2.1 0.9 0.0 0.4 0.3 0.0 0.0 0.0 0.0 RTBDN FLJ36353 ENSG00000132026 Retbindin Q9BSG5 19 12825478-12835428 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 288.0" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 350.3;Rod photoreceptor cells: 524.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 8.3;SH-SY5Y: 5.4;U-266/84: 23.1;U-87 MG: 4.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA052511 Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA052511: AB_2797243" "unprognostic (4.55e-4)" "unprognostic (3.94e-3)" "unprognostic (2.18e-1)" "unprognostic (1.54e-4)" "unprognostic (3.33e-2)" "unprognostic (2.18e-1)" "unprognostic (1.08e-2)" "unprognostic (2.45e-2)" "unprognostic (2.02e-2)" "unprognostic (3.55e-1)" "unprognostic (6.48e-2)" "unprognostic (7.04e-3)" "unprognostic (7.66e-9)" "unprognostic (3.55e-2)" "unprognostic (1.00e-1)" "unprognostic (7.05e-2)" "unprognostic (2.24e-2)" 0.0 3.5 5.1 0.1 5.9 0.2 0.0 1.9 10.0 0.0 0.9 1.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 6.7 2.7 0.0 0.0 0.1 0.0 2.7 1.9 0.0 1.2 0.3 34.3 0.0 5.8 0.0 0.3 288.0 0.0 0.0 0.0 0.1 0.5 0.1 0.9 0.0 1.1 3.3 2.9 8.7 0.0 0.0 0.0 0.0 0.1 3.2 0.9 0.1 0.1 0.6 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.3 0.0 0.9 0.9 0.0 0.6 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.9 0.0 0.1 2.4 0.0 0.0 0.4 0.2 0.0 0.0 0.1 1.3 2.7 0.0 0.1 0.1 0.0 0.9 0.7 1.1 0.7 0.1 1.1 0.1 0.0 8.3 5.4 0.1 0.0 0.4 0.4 2.8 0.7 0.0 0.8 1.0 0.7 0.1 1.2 23.1 4.3 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.1 5.9 1.9 10.0 6.7 2.7 2.7 1.9 5.8 0.9 2.9 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 50.5 0.0 0.0 1.4 0.0 0.1 0.0 350.3 0.0 0.0 0.5 0.0 0.0 0.5 0.1 0.0 1.8 0.0 0.0 2.8 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.6 2.5 0.6 4.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 84.4 0.0 1.0 0.7 0.1 0.1 0.0 0.5 0.0 0.7 0.1 0.0 524.0 0.0 0.1 0.0 16.2 5.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 RTF1 KIAA0252 ENSG00000137815 "RTF1 homolog, Paf1/RNA polymerase II complex component" Q92541 15 41408408-41483563 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006714, CAB079946, CAB079947" Supported Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "CAB079946: , CAB079947: , HPA006714: AB_1079855" "unprognostic (1.10e-1)" "unprognostic (5.03e-2)" "unprognostic (1.40e-1)" "unprognostic (1.86e-2)" "unprognostic (1.21e-2)" "unprognostic (1.88e-1)" "unprognostic (8.87e-2)" "unprognostic (5.36e-2)" "unprognostic (4.21e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.19e-1)" "unprognostic (1.69e-2)" "unprognostic (8.22e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (9.50e-2)" 17.8 23.2 24.7 18.8 26.3 45.1 22.4 26.8 42.7 24.3 19.2 21.6 19.2 25.1 19.5 21.4 17.1 20.3 24.6 27.1 24.0 19.0 19.9 19.4 28.2 21.0 21.3 29.4 16.6 36.9 11.4 24.5 20.9 23.4 22.4 26.4 16.7 22.8 49.4 25.9 19.8 26.3 20.0 23.8 20.8 29.8 23.9 28.8 29.5 34.8 25.0 23.1 17.5 24.6 32.0 20.6 66.5 54.2 37.0 43.4 31.2 41.8 46.8 56.0 46.5 40.4 19.8 30.2 33.0 43.9 24.9 55.3 38.9 34.8 47.6 46.2 36.1 63.5 45.2 30.4 25.8 57.2 35.5 31.4 34.3 30.0 30.1 41.6 45.8 54.0 49.2 34.0 46.5 24.2 55.1 35.1 35.9 39.6 28.0 59.0 51.8 28.9 36.5 67.5 34.0 44.9 37.6 47.4 19.0 35.9 38.9 54.5 37.9 54.6 34.4 54.8 46.5 38.9 65.0 49.6 39.4 53.5 34.1 5.4 3.1 6.9 3.4 2.1 3.1 6.9 3.3 2.9 2.2 5.3 4.0 3.2 8.5 6.2 2.7 5.5 4.3 1.1 24.7 26.3 26.8 42.7 27.1 24.0 21.0 21.3 20.9 20.0 23.9 24.6 118.0 128.2 80.1 23.8 109.0 145.0 98.7 120.4 102.4 213.5 152.6 129.7 94.3 111.5 89.7 123.2 93.8 168.3 117.1 129.6 164.4 103.0 333.7 103.9 162.6 116.4 87.8 85.0 40.3 110.5 119.1 103.5 71.9 126.2 91.2 127.9 129.5 193.2 95.5 148.0 43.6 145.4 109.9 86.7 94.4 348.5 145.1 83.0 108.5 15.9 116.1 106.2 128.8 16.6 23.5 127.0 105.1 159.9 104.1 141.9 112.6 186.4 70.7 188.2 85.5 115.4 146.9 198.3 59.9 83.4 163.0 219.3 113.0 126.1 133.2 99.2 RTN4 "ASY, KIAA0886, NOGO, NSP-CL" ENSG00000115310 "Reticulon 4" Q9NQC3 2 54972187-55112621 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 3547.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 95.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1801.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005388, HPA023977" Supported Enhanced "Endoplasmic reticulum" NA NA 3400000 "Cluster 38: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "CAB005388: AB_2285559, HPA023977: AB_2671391" "unprognostic (1.31e-2)" "unprognostic (1.71e-3)" "unprognostic (6.76e-2)" "unprognostic (1.28e-3)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.00e-4)" "unprognostic (5.79e-2)" "unprognostic (1.84e-3)" "unprognostic (2.47e-1)" "unprognostic (1.97e-1)" "unprognostic (3.91e-3)" "unprognostic (4.38e-1)" "unprognostic (4.41e-2)" "unprognostic (1.29e-2)" "unprognostic (4.99e-2)" "unprognostic (1.27e-1)" "unprognostic (4.91e-2)" 586.2 302.7 376.3 150.9 461.9 115.4 253.1 465.9 534.3 118.0 297.1 186.9 236.2 153.9 176.5 217.9 130.0 196.8 166.0 411.8 431.6 442.5 551.9 211.8 83.6 498.6 456.5 132.0 122.7 236.7 84.0 177.3 524.8 223.9 179.2 640.6 127.1 183.4 996.0 252.9 292.5 246.4 440.8 110.3 124.0 78.6 453.2 87.1 130.7 777.9 88.2 291.2 147.9 591.2 402.9 285.3 273.3 71.7 908.4 845.0 153.2 1301.6 1097.4 393.5 365.7 235.5 371.7 87.1 673.8 889.9 657.7 355.6 181.5 524.4 596.2 248.3 139.4 120.3 159.6 376.6 1801.9 218.1 59.7 638.5 490.8 540.3 1041.9 792.3 751.3 215.6 249.8 195.0 1724.1 117.8 268.3 222.0 245.9 86.8 252.0 118.5 360.3 180.0 924.0 475.9 179.2 211.3 297.7 173.3 378.1 465.1 147.2 165.1 1074.9 764.8 326.1 304.8 756.5 118.0 103.4 56.1 778.7 247.9 630.1 95.8 9.5 27.5 9.2 11.6 7.6 6.8 14.7 8.2 9.2 3.8 24.1 10.2 15.6 41.1 19.0 13.7 37.6 9.9 376.3 461.9 465.9 534.3 411.8 431.6 498.6 456.5 524.8 440.8 453.2 591.2 451.4 176.3 203.4 201.4 102.3 1062.1 1456.6 367.0 225.9 644.6 297.6 260.6 182.0 243.1 251.0 676.8 379.5 529.6 173.6 408.6 291.6 559.7 459.7 316.6 264.6 308.0 222.1 98.2 454.5 323.4 611.9 421.9 98.4 324.7 150.4 161.5 181.3 633.4 669.1 425.7 370.4 280.5 231.9 339.0 578.4 266.6 167.4 371.7 341.5 215.5 396.4 3547.4 137.0 249.3 1334.3 571.2 309.7 226.1 81.6 921.4 897.1 678.3 233.6 540.0 216.9 420.5 324.6 382.7 90.1 247.1 1059.3 362.0 145.5 100.1 238.1 1226.5 RTN4RL1 "DKFZp547J144, NgR3, NGRH2" ENSG00000185924 "Reticulon 4 receptor like 1" Q86UN2 17 1934677-2025334 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 20.6;Cone photoreceptor cells: 37.5;Excitatory neurons: 43.5;Horizontal cells: 33.7;Inhibitory neurons: 18.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 12.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.9;HaCaT: 10.8;hTCEpi: 10.1;T-47d: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044428 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Midbody" "Intracellular and membrane" Yes NA 35000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "Nucleoplasm, Plasma membrane, Midbody" "HPA044428: AB_10963229" "unprognostic (5.23e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.93e-2)" "unprognostic (7.25e-2)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (8.97e-3)" "unprognostic (6.21e-2)" "unprognostic (2.55e-3)" "unprognostic (6.32e-3)" "prognostic unfavorable (7.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (3.15e-2)" 4.0 3.1 4.6 0.3 4.0 0.0 6.4 0.0 9.2 2.1 0.0 0.4 0.1 0.8 0.2 1.3 1.5 0.6 2.3 12.3 0.3 1.6 2.6 1.6 0.1 0.0 0.5 0.9 1.8 1.3 5.9 0.3 0.0 3.4 0.1 8.5 4.4 2.0 1.8 9.6 0.5 0.3 0.0 1.1 0.7 0.8 1.9 0.2 1.4 0.4 0.1 1.5 2.2 0.0 1.4 1.6 1.8 2.5 2.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.0 0.0 0.1 10.9 0.2 10.8 4.6 0.1 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 10.1 0.0 3.6 0.0 0.0 2.5 0.1 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.3 0.8 0.3 1.2 0.0 0.0 2.2 0.0 0.3 0.8 1.7 0.2 13.3 0.1 0.0 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.0 0.0 9.2 12.3 0.3 0.0 0.5 0.0 0.0 1.9 0.0 1.0 0.0 2.2 1.6 0.1 2.7 0.2 0.0 1.8 20.6 5.4 4.3 3.0 1.5 1.3 3.7 37.5 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.0 0.7 0.0 0.0 43.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.1 3.3 1.8 33.7 18.6 0.0 0.0 0.3 0.4 1.1 0.0 0.1 3.6 7.5 0.0 1.8 0.0 8.5 1.7 0.1 0.0 0.0 0.1 0.9 0.0 0.1 1.5 10.0 0.0 0.0 0.6 0.0 0.2 0.5 2.8 0.0 0.2 0.0 0.0 0.3 RTN4RL2 "NgR2, NGRH1" ENSG00000186907 "Reticulon 4 receptor like 2" Q86UN3 11 57460528-57477534 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 39.1;liver: 40.7;thyroid gland: 30.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 19.9;Cholangiocytes: 12.8;Excitatory neurons: 16.7;Hepatocytes: 14.0;Oligodendrocyte precursor cells: 9.5;Spermatocytes: 10.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HMC-1: 44.1;Karpas-707: 67.5;REH: 42.3;RPMI-8226: 134.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "amygdala: 13.5;cerebral cortex: 23.8;hippocampal formation: 21.0" "Intracellular and membrane" NA NA 27000000 "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (6.27e-3)" "unprognostic (2.02e-2)" "unprognostic (4.57e-2)" "unprognostic (8.40e-2)" "unprognostic (8.51e-2)" "unprognostic (7.64e-2)" "unprognostic (6.83e-2)" "unprognostic (3.72e-2)" "unprognostic (7.27e-2)" "unprognostic (2.41e-1)" "unprognostic (1.09e-2)" "unprognostic (3.28e-1)" "prognostic unfavorable (3.05e-7)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" "unprognostic (5.16e-3)" "unprognostic (2.18e-2)" 4.1 0.7 19.0 0.3 39.1 0.8 3.5 0.0 27.3 2.1 0.0 1.0 1.1 2.0 0.2 1.6 1.7 3.0 3.3 25.2 0.0 2.8 40.7 2.6 0.4 0.0 0.0 1.1 2.4 3.7 3.6 1.9 0.0 1.6 0.1 1.0 3.4 0.3 1.7 4.3 1.1 0.7 0.0 1.0 1.5 1.8 0.0 1.9 30.5 0.4 0.3 1.2 1.6 8.2 7.4 10.1 7.6 13.1 3.1 4.4 1.0 0.1 2.9 0.3 2.7 1.3 1.4 0.2 0.2 0.4 4.3 0.2 11.9 0.2 0.1 1.7 4.7 2.3 1.1 7.2 4.4 1.7 44.1 11.9 1.3 1.1 1.1 1.3 0.1 12.9 1.6 67.5 0.1 1.4 0.2 5.3 13.3 0.5 7.6 42.3 5.4 134.0 0.1 0.2 14.0 1.2 1.1 0.6 7.7 0.6 8.5 2.0 0.1 0.5 22.7 3.1 2.4 4.1 9.2 1.4 16.7 7.3 5.8 0.0 0.3 0.0 0.0 0.6 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 19.0 39.1 0.0 27.3 25.2 0.0 0.0 0.0 0.0 0.0 0.0 8.2 1.7 0.0 0.0 2.0 0.4 5.7 0.4 0.3 2.8 19.9 2.1 1.5 0.4 12.8 0.1 0.0 0.0 0.0 0.9 0.2 3.9 1.3 2.6 0.6 0.9 2.1 1.8 0.8 16.7 0.6 5.5 1.6 0.5 2.1 0.0 0.0 1.1 14.0 0.4 0.0 1.1 0.6 0.0 0.0 2.1 1.3 0.3 0.6 1.8 3.7 0.5 0.8 2.1 9.5 1.2 0.8 0.1 1.2 0.0 1.0 0.0 1.1 0.0 1.4 6.6 1.0 5.4 10.2 1.7 1.1 2.8 0.0 0.9 0.1 0.2 0.2 RTTN DKFZP434G145 ENSG00000176225 Rotatin Q86VV8 18 70003031-70205726 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 69.3;Oligodendrocyte precursor cells: 48.7;Oligodendrocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTERT-HME1: 21.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041343, HPA041967, HPA075089" Uncertain Approved Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Centrosome "HPA041343: AB_10794409, HPA041967: AB_10796790, HPA075089: " "unprognostic (1.76e-1)" "unprognostic (2.13e-1)" "unprognostic (1.36e-1)" "unprognostic (4.11e-2)" "unprognostic (3.44e-2)" "unprognostic (6.16e-3)" "unprognostic (4.63e-3)" "unprognostic (2.36e-1)" "unprognostic (1.40e-1)" "unprognostic (4.66e-2)" "unprognostic (1.90e-1)" "unprognostic (8.25e-2)" "unprognostic (6.94e-3)" "unprognostic (1.07e-1)" "unprognostic (3.81e-1)" "unprognostic (1.32e-1)" "unprognostic (1.96e-2)" 1.4 1.2 3.5 1.6 5.0 3.1 2.1 3.6 3.4 1.5 2.1 1.3 1.1 1.8 1.5 1.1 1.6 1.2 2.8 2.6 3.0 2.3 2.7 1.6 2.2 4.5 4.0 2.7 1.8 1.7 0.8 1.6 5.1 1.1 1.5 4.1 1.3 0.6 1.8 1.3 1.3 1.0 4.2 2.0 1.3 3.3 6.0 3.6 0.9 1.1 1.9 0.9 1.1 7.1 4.4 6.6 9.4 2.7 1.8 2.0 3.9 7.5 3.4 6.8 7.0 2.5 2.5 3.8 1.0 4.7 6.0 5.4 6.9 11.0 11.1 13.1 3.0 4.1 5.9 3.1 1.3 7.7 4.0 1.6 10.9 7.2 21.2 3.1 4.2 5.8 4.3 8.4 6.1 2.0 7.4 2.1 1.8 1.0 5.8 6.0 8.6 3.9 1.1 3.2 4.0 4.3 4.6 2.6 2.8 6.2 2.8 4.4 3.4 8.8 2.3 3.1 5.7 4.1 3.8 7.8 5.1 4.9 6.0 0.2 0.2 0.1 0.2 0.0 0.4 0.6 0.4 0.3 0.0 0.2 0.6 0.3 0.1 0.3 0.0 0.2 0.3 0.1 3.5 5.0 3.6 3.4 2.6 3.0 4.5 4.0 5.1 4.2 6.0 7.1 6.1 0.0 8.6 19.6 7.1 1.5 1.7 10.1 1.8 8.2 3.9 3.9 5.0 1.5 5.7 0.0 0.0 4.0 4.9 2.9 0.0 1.1 10.6 6.0 5.2 3.4 0.0 4.2 25.4 1.6 1.9 4.0 6.1 6.0 5.1 10.9 1.8 3.7 2.3 16.8 25.8 1.5 2.0 1.3 1.4 3.2 2.1 3.3 0.0 69.3 1.3 1.9 3.1 48.7 110.8 2.0 2.4 1.9 14.7 1.1 2.2 4.1 1.7 9.7 13.1 5.1 4.0 10.6 6.7 3.5 1.7 3.0 5.8 2.5 2.6 2.3 RUSF1 "C16orf58, FLJ13868" ENSG00000140688 "RUS family member 1" Q96GQ5 16 31489471-31509309 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.8;Cytotrophoblasts: 22.3;Extravillous trophoblasts: 21.0;Hofbauer cells: 14.8;Syncytiotrophoblasts: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024406 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA024406: AB_1845580" "unprognostic (1.46e-2)" "unprognostic (2.52e-2)" "unprognostic (2.25e-2)" "unprognostic (4.22e-1)" "unprognostic (6.21e-2)" "unprognostic (3.05e-2)" "unprognostic (2.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (9.89e-2)" "unprognostic (3.20e-1)" "unprognostic (1.58e-1)" "unprognostic (6.34e-3)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "unprognostic (5.69e-2)" "unprognostic (2.24e-2)" 27.1 31.8 19.6 20.0 18.9 21.5 28.8 12.0 21.3 45.4 14.2 29.6 31.3 43.2 20.7 26.5 38.2 23.0 28.5 19.9 19.7 29.5 57.9 25.0 19.8 17.0 16.0 49.6 56.8 46.2 48.4 25.7 18.5 39.1 19.1 22.4 64.8 34.2 9.4 26.9 30.3 25.6 13.8 22.3 39.5 21.4 17.0 18.0 42.0 9.8 15.6 31.8 31.4 17.0 28.6 37.2 22.7 39.7 51.7 34.3 42.3 33.4 56.6 25.5 30.2 11.3 49.1 24.5 69.4 49.8 32.9 39.0 22.9 31.0 11.8 35.8 23.0 24.8 20.6 28.8 74.8 29.4 28.6 41.7 33.1 33.7 68.5 50.2 24.9 38.4 37.3 40.9 25.3 53.9 13.7 19.8 17.8 41.8 24.1 31.1 34.2 74.8 29.3 17.6 24.8 38.2 25.2 65.3 52.8 21.5 56.6 42.9 22.0 44.3 24.7 28.7 22.1 59.0 37.0 18.8 56.7 44.7 62.5 3.1 5.7 7.6 7.8 8.4 7.2 6.7 8.2 7.8 9.7 6.3 7.9 7.0 0.9 9.4 8.1 8.9 9.4 7.2 19.6 18.9 12.0 21.3 19.9 19.7 17.0 16.0 18.5 13.8 17.0 17.0 5.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 22.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 21.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 22.3 0.4 0.0 0.0 0.0 RUVBL2 "ECP51, INO80J, Reptin52, RVB2, TIH2, TIP48, TIP49b" ENSG00000183207 "RuvB like AAA ATPase 2" Q9Y230 19 48993562-49015970 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 614.5;Late spermatids: 945.1;Respiratory ciliated cells: 253.6;Spermatocytes: 394.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012432, HPA042880, HPA067966" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA NA 53000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" Centrosome "CAB012432: , HPA042880: AB_2678210, HPA067966: AB_2685933" "unprognostic (1.71e-1)" "unprognostic (9.06e-3)" "unprognostic (3.51e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (9.28e-4)" "unprognostic (7.06e-3)" "unprognostic (6.25e-2)" "unprognostic (3.28e-1)" "unprognostic (8.13e-2)" "unprognostic (7.58e-2)" "unprognostic (2.81e-2)" "unprognostic (2.21e-2)" "unprognostic (7.61e-3)" "unprognostic (1.61e-1)" "unprognostic (2.58e-1)" 23.4 21.7 41.4 26.7 42.9 51.4 22.6 44.6 54.6 23.5 48.9 29.8 27.9 19.3 15.3 36.7 72.2 15.8 37.0 44.7 42.6 19.4 24.0 19.6 30.8 42.4 45.8 25.8 34.5 28.2 6.5 24.0 44.2 20.2 17.4 14.9 32.5 25.4 60.3 30.7 24.7 19.0 41.4 20.6 22.6 110.7 43.8 38.9 23.8 39.1 21.3 22.6 7.2 52.3 236.5 346.0 63.3 250.2 45.0 50.9 88.8 105.4 86.3 214.9 162.5 267.4 148.7 219.9 78.5 106.8 93.7 134.6 99.9 210.3 68.5 99.2 323.7 158.8 196.7 241.0 119.1 318.8 96.8 78.0 68.0 145.0 113.5 59.2 114.1 232.8 266.6 121.3 90.5 195.2 234.1 218.5 122.6 162.4 152.4 227.4 156.9 155.8 110.5 182.7 155.7 169.9 132.2 164.2 66.2 30.4 125.9 179.4 104.8 100.8 135.1 63.8 318.1 171.4 177.1 223.6 76.2 174.6 156.4 51.1 54.9 18.9 42.6 52.4 46.8 54.5 45.2 42.3 65.9 52.6 42.9 40.0 3.7 47.4 48.5 48.9 49.2 55.4 41.4 42.9 44.6 54.6 44.7 42.6 42.4 45.8 44.2 41.4 43.8 52.3 16.5 12.8 20.7 4.2 25.3 27.8 52.0 89.8 37.5 17.5 30.4 33.7 48.5 24.3 55.7 33.1 33.3 104.6 15.0 33.8 46.9 78.3 614.5 131.7 29.6 27.3 17.5 58.1 6.1 71.8 81.8 36.6 28.5 25.4 13.3 32.8 23.2 34.2 51.1 18.5 5.2 38.5 52.9 22.9 25.5 945.1 36.1 18.9 26.6 1.9 35.5 31.2 27.8 4.5 5.6 56.0 30.6 42.9 41.3 43.5 33.1 70.4 253.6 31.4 19.7 28.9 65.4 394.2 43.9 49.2 27.6 115.9 20.8 37.1 61.0 38.8 RXRA NR2B1 ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 218.9;Kupffer cells: 134.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 19.5" "Group enriched" "Detected in many" 5 "granulocytes: 19.5;monocytes: 12.9" "Cell line enhanced" "Detected in many" "HaCaT: 105.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Golgi apparatus" "CAB004565: AB_2184877, CAB005352: AB_2184874" "unprognostic (2.68e-1)" "unprognostic (7.94e-2)" "unprognostic (3.67e-2)" "unprognostic (7.22e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-3)" "prognostic favorable (7.02e-4)" "unprognostic (7.72e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" 40.5 22.7 33.5 14.5 36.4 18.9 11.2 25.5 29.4 12.2 16.9 16.6 25.8 13.5 8.7 28.5 16.5 13.6 19.4 27.1 30.2 16.0 32.9 18.8 8.2 32.9 31.3 21.7 25.4 45.1 3.5 14.5 30.8 15.6 10.0 5.4 21.7 17.1 106.5 88.1 28.0 11.1 30.4 25.1 14.7 7.9 42.7 6.0 17.6 51.9 7.6 16.2 8.2 22.6 19.6 36.4 14.7 21.9 42.8 19.1 66.7 14.1 16.1 9.6 6.5 20.7 28.0 0.0 25.8 22.5 15.1 105.5 7.7 32.8 2.9 26.3 7.2 0.1 47.5 30.0 20.4 18.8 4.8 29.0 52.1 11.5 10.6 12.9 12.8 1.6 26.0 1.1 8.7 61.8 1.1 59.5 17.5 63.4 16.9 7.4 30.3 36.7 12.2 64.3 17.2 10.5 37.3 46.9 10.6 7.1 44.9 78.8 16.5 16.2 23.4 17.4 9.7 1.7 0.2 0.4 11.6 33.9 12.7 1.3 8.1 6.6 1.4 12.9 0.2 0.3 0.9 1.0 3.2 0.1 0.2 1.2 19.5 2.2 11.2 0.7 1.2 3.2 33.5 36.4 25.5 29.4 27.1 30.2 32.9 31.3 30.8 30.4 42.7 22.6 32.1 32.1 22.9 36.2 4.6 34.5 16.5 21.1 12.5 6.0 16.7 14.4 38.8 72.9 26.2 9.2 25.0 30.1 11.0 72.3 1.9 13.9 4.3 19.8 16.6 28.9 9.6 30.9 9.1 14.1 29.5 23.7 17.9 17.4 1.3 21.3 71.0 218.9 31.9 33.7 17.6 21.2 10.2 134.2 30.0 18.8 32.3 50.4 12.4 10.3 80.4 36.5 14.4 29.1 6.0 15.9 32.4 21.1 7.4 17.7 55.6 19.9 34.4 19.9 19.7 34.6 30.6 0.9 9.4 34.4 46.9 23.9 12.6 15.5 27.5 32.8 RYR3 ENSG00000198838 "Ryanodine receptor 3" Q15413 15 33310962-33866121 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.7;choroid plexus: 33.3;skeletal muscle: 24.2;tongue: 44.2" "Cell type enriched" "Detected in many" 4 "Astrocytes: 788.8" "Cancer enriched" "Detected in single" 4 "glioma: 1.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 1.9" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in some" "A549: 4.4;RH-30: 6.5;RPTEC TERT1: 3.1;SuSa: 2.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 23.4" HPA062004 Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 70: Brain - Nervous system development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA062004: AB_2797267" "unprognostic (5.85e-2)" "unprognostic (1.57e-1)" "unprognostic (5.30e-2)" "unprognostic (1.35e-1)" "unprognostic (1.26e-2)" "unprognostic (8.03e-4)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.85e-2)" "unprognostic (7.10e-2)" "unprognostic (8.25e-3)" "unprognostic (2.36e-1)" "unprognostic (2.48e-2)" "unprognostic (1.86e-2)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (1.91e-1)" 1.7 0.7 35.2 0.2 43.7 1.4 2.0 33.5 39.7 4.2 33.3 10.1 0.4 7.2 0.1 1.2 5.4 0.5 0.2 35.6 29.3 2.0 0.0 0.3 0.1 35.5 30.2 0.9 0.1 6.1 1.3 0.1 33.5 1.4 1.3 2.2 0.5 2.0 24.2 1.0 1.8 4.4 24.3 0.5 2.1 0.5 37.1 0.6 0.3 44.2 0.4 4.0 2.8 28.8 0.2 4.4 0.9 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 1.1 0.1 0.2 0.4 0.0 1.4 0.1 0.0 0.0 0.0 0.2 0.1 0.9 0.1 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 1.6 0.0 0.2 0.1 0.1 0.7 0.2 0.1 0.3 6.5 0.1 3.1 0.3 0.1 0.3 0.4 0.0 0.1 2.8 0.0 0.2 0.5 0.1 0.1 0.0 0.4 0.2 0.9 0.4 0.3 1.4 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.2 43.7 33.5 39.7 35.6 29.3 35.5 30.2 33.5 24.3 37.1 28.8 2.9 0.0 1.1 788.8 0.2 0.4 0.0 0.0 0.0 8.0 0.2 2.5 2.2 0.0 0.6 0.0 0.0 0.6 0.5 0.0 0.0 0.0 15.5 7.7 1.4 1.8 0.0 8.4 162.5 0.0 0.7 0.6 0.0 8.0 14.0 0.2 0.0 0.0 1.0 69.0 115.2 0.0 0.0 0.0 1.0 41.9 0.3 0.3 0.0 36.5 0.6 0.3 0.0 22.1 5.9 0.0 0.0 0.0 0.1 0.0 0.0 0.3 5.9 0.8 0.0 51.3 0.4 0.1 1.5 0.0 0.6 0.1 0.4 2.5 0.0 0.0 S1PR3 "EDG-3, EDG3" ENSG00000213694 "Sphingosine-1-phosphate receptor 3" "Q99500, Q6ZRZ4" 9 88990863-89005155 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 55.5;Sertoli cells: 65.7;Smooth muscle cells: 35.0;Theca cells: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "classical monocyte: 7.0" "Lineage enriched" "Detected in single" 18 "monocytes: 7.0" "Cell line enhanced" "Detected in many" "AF22: 116.0;ASC diff: 157.9;ASC TERT1: 158.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "prognostic favorable (5.91e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.91e-3)" "unprognostic (2.02e-1)" "unprognostic (4.41e-2)" "unprognostic (2.77e-2)" "unprognostic (5.22e-2)" "unprognostic (1.94e-2)" "unprognostic (3.15e-1)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.91e-6)" "unprognostic (4.43e-2)" "unprognostic (1.48e-2)" "unprognostic (3.93e-2)" "unprognostic (1.37e-1)" 18.3 25.0 5.8 10.6 6.4 3.2 11.2 6.9 6.7 32.2 10.7 14.8 4.5 17.2 6.2 17.6 26.0 14.2 17.5 6.3 11.2 36.9 6.1 8.9 11.4 16.1 9.8 5.1 11.7 1.7 17.0 15.1 7.7 20.1 3.4 4.2 3.9 11.9 4.4 3.1 10.7 36.0 8.4 13.2 12.5 2.2 12.4 4.7 4.8 8.2 9.4 20.4 20.9 13.2 0.5 17.7 116.0 6.0 157.9 158.7 0.1 24.8 61.4 17.0 17.0 0.2 0.0 0.0 0.3 37.2 16.6 0.2 0.3 18.0 11.5 0.0 1.2 0.0 23.3 0.1 13.7 8.1 0.1 28.6 1.0 22.2 4.0 13.2 29.9 17.0 2.1 0.1 4.7 17.1 14.3 8.7 11.2 0.8 6.2 1.5 0.0 0.1 0.3 7.1 1.5 8.1 23.4 5.7 0.0 22.8 2.7 7.4 60.3 25.4 10.3 27.8 4.1 0.0 0.1 0.0 36.8 7.1 9.1 0.3 7.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 2.1 5.8 6.4 6.9 6.7 6.3 11.2 16.1 9.8 7.7 8.4 12.4 13.2 3.0 0.0 1.7 3.6 0.0 10.1 9.5 1.8 2.8 1.0 9.9 3.7 9.2 1.5 1.7 1.8 2.1 17.9 0.1 0.0 0.0 0.3 0.0 2.1 55.5 10.6 0.0 0.0 0.5 0.5 1.3 21.5 0.5 2.4 0.0 3.8 1.8 1.6 2.4 3.3 1.7 0.0 0.0 1.8 4.0 0.5 3.7 4.4 0.0 7.5 6.9 7.1 0.0 0.0 0.2 0.9 0.0 6.8 0.2 7.0 0.0 1.4 2.9 1.6 65.7 16.1 35.0 0.0 1.2 1.5 3.3 5.5 2.2 65.8 0.0 6.4 SAA1 "PIG4, SAA, TP53I4" ENSG00000173432 "Serum amyloid A1" P0DJI8 11 18266260-18269977 "Disease related genes, Predicted secreted proteins" "Acute phase" Heparin-binding Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 48144.3" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 99298.7" "Cancer enriched" "Detected in many" 16 "liver cancer: 1249.6" "Group enriched" "Detected in some" 5 "midbrain: 3.8;pons: 2.6;thalamus: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HBEC3-KT: 716.4" "Secreted to blood" NA NA 300000000 11000000000 "Cluster 7: Monocytes - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.86e-3)" "unprognostic (1.41e-1)" "unprognostic (2.82e-1)" "unprognostic (1.50e-1)" "unprognostic (4.54e-3)" "unprognostic (1.79e-2)" "unprognostic (1.63e-2)" "unprognostic (7.04e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-2)" "unprognostic (8.95e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.57e-12)" "unprognostic (5.15e-2)" "unprognostic (9.78e-2)" "unprognostic (9.23e-3)" "unprognostic (1.64e-1)" 2040.4 54.4 0.1 161.7 0.2 0.0 1382.7 0.1 0.6 258.0 1.8 40.3 1.4 2.2 0.2 51.1 56.6 33.6 23.2 0.3 0.3 29.5 48144.3 98.5 1.1 0.8 3.8 3.3 46.7 0.5 66.6 7.2 2.6 66.5 6.4 0.0 2368.1 4.4 511.6 88.6 75.0 18.8 0.1 38.8 42.0 1.7 6.0 52.1 18.1 0.2 15.7 63.9 29.0 0.1 49.2 0.3 0.0 0.3 34.4 0.2 18.9 1.3 1.1 0.2 0.3 0.1 17.2 0.0 38.3 0.0 11.7 45.5 0.0 716.4 0.3 0.6 0.0 0.8 0.0 0.1 148.4 1.1 0.0 60.9 66.7 0.2 76.7 0.1 0.0 0.0 0.1 0.0 9.3 0.1 0.0 0.1 0.0 0.0 0.0 0.2 1.7 0.0 28.5 0.9 0.0 0.1 4.2 5.5 0.2 0.0 0.5 0.0 0.0 0.2 5.5 0.0 1.3 0.0 1.3 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.3 0.3 0.8 3.8 2.6 0.1 6.0 0.1 107.2 6.4 2.8 0.0 259.8 9.3 64.9 10039.5 10.2 0.0 210.6 1010.4 0.1 1701.5 7604.7 55.2 0.0 1.3 3.0 44.5 0.0 250.4 0.0 12.6 1.6 114.9 1.8 3543.7 0.1 81.1 34.4 8.3 0.0 14.3 2.5 0.0 2568.6 99298.7 1.0 0.0 0.1 5.2 2012.1 2454.9 0.3 0.0 0.0 2.6 51.6 0.0 2.6 0.0 1.0 0.0 0.1 68.8 5.5 0.0 0.1 185.5 3.1 0.2 15716.2 0.0 0.0 31.5 736.1 0.0 0.0 34.1 0.1 2.1 214.7 0.0 36.7 178.8 SAA2 ENSG00000134339 "Serum amyloid A2" P0DJI9 11 18239223-18248668 "Disease related genes, Predicted secreted proteins" "Acute phase" Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 36265.6" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 55342.6" "Cancer enriched" "Detected in many" 22 "liver cancer: 150.5" "Group enriched" "Detected in some" 9 "midbrain: 6.3;pons: 4.8;thalamus: 7.7" "Immune cell enhanced" "Detected in some" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 27.8;EFO-21: 20.2;GAMG: 19.6;HaCaT: 25.0;HBEC3-KT: 55.4;HSkMC: 17.6" "Secreted to blood" NA NA 9200000000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.73e-3)" "unprognostic (4.42e-2)" "unprognostic (2.63e-1)" "unprognostic (5.03e-2)" "unprognostic (1.40e-3)" "unprognostic (7.12e-2)" "unprognostic (7.45e-2)" "unprognostic (2.15e-2)" "unprognostic (1.57e-1)" "unprognostic (2.86e-2)" "unprognostic (2.78e-2)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.30e-8)" "unprognostic (1.53e-1)" "unprognostic (9.72e-2)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" 562.3 16.9 0.0 137.9 0.1 0.4 321.5 0.5 0.7 277.0 0.6 11.5 0.9 1.0 0.2 22.1 21.1 14.0 8.3 0.1 0.1 12.8 36265.6 35.7 0.6 0.2 6.3 1.7 13.9 0.2 31.1 1.7 4.8 38.5 1.3 0.6 1796.2 1.6 221.2 25.7 21.0 6.5 0.0 20.1 18.1 2.1 7.7 16.3 6.6 0.2 6.8 22.4 7.8 0.7 27.8 0.1 0.2 0.2 1.0 0.0 3.6 0.1 0.8 0.1 0.3 0.0 12.1 0.1 20.2 0.2 19.6 25.0 0.0 55.4 0.1 1.2 0.0 1.0 0.5 0.0 7.8 0.8 0.1 17.6 7.4 0.0 8.9 0.6 0.2 0.0 0.0 0.9 1.5 0.0 0.2 0.0 0.5 0.4 0.0 0.2 0.7 0.0 12.4 1.3 0.3 0.0 1.7 8.5 0.1 0.5 0.4 0.5 0.2 0.2 1.2 0.5 1.2 0.5 0.3 1.7 0.1 1.1 0.3 1.0 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.4 0.1 0.1 1.1 0.1 0.2 0.2 0.2 0.1 0.0 0.1 0.5 0.7 0.1 0.1 0.2 6.3 4.8 0.0 7.7 0.7 7.6 0.0 1.5 0.0 184.4 1.0 5.6 4629.9 0.6 0.0 56.8 68.5 0.2 1052.3 4596.4 3.7 0.0 0.4 0.8 21.9 0.0 70.3 1.6 12.3 0.9 68.2 0.0 2356.0 0.0 34.4 2.3 2.0 0.0 13.5 0.0 0.0 1442.8 55342.6 0.4 0.0 0.0 1.1 1204.4 1502.7 0.0 0.5 0.0 0.6 8.8 0.0 1.0 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.1 34.5 2.9 0.1 11449.8 0.0 0.0 3.1 400.9 0.3 0.0 5.6 0.1 0.5 144.2 0.0 5.3 65.4 SAA4 "C-SAA, CSAA" ENSG00000148965 "Serum amyloid A4, constitutive" P35542 11 18231355-18236802 "Plasma proteins, Predicted secreted proteins" "Acute phase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 124 "liver: 1943.5" "Group enriched" "Detected in some" 7 "Hepatocytes: 2132.8;Respiratory ciliated cells: 706.8" "Cancer enriched" "Detected in many" 141 "liver cancer: 118.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "Hep G2: 28.8" "Not detected" "Not detected" "CAB026061, HPA060139" Supported "Secreted to blood" NA NA 65000000000 33000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB026061: , HPA060139: AB_2684210" "unprognostic (4.70e-4)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (4.83e-1)" "unprognostic (4.15e-2)" "unprognostic (6.05e-2)" "unprognostic (3.63e-3)" "unprognostic (5.94e-2)" "unprognostic (2.40e-2)" "unprognostic (1.41e-1)" "unprognostic (7.35e-2)" "unprognostic (2.54e-8)" "unprognostic (2.49e-1)" "unprognostic (6.46e-2)" 7.4 0.5 0.3 0.4 0.3 0.0 6.7 0.3 0.6 15.6 0.3 0.2 0.0 0.0 0.2 0.5 0.5 1.0 0.1 0.3 0.3 0.4 1943.5 0.7 0.0 0.4 0.4 0.0 0.1 0.0 0.8 0.0 0.3 1.2 0.0 0.1 11.4 0.1 3.4 0.5 0.1 0.1 0.3 1.2 0.1 1.3 0.4 0.9 0.0 0.0 0.2 0.1 0.1 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.5 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.3 0.1 28.8 0.3 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.6 0.3 0.3 0.4 0.4 0.3 0.3 0.4 0.5 0.1 0.0 0.0 0.0 2.5 0.0 0.0 184.7 0.0 0.0 2.1 1.4 0.0 18.6 172.6 0.0 0.0 0.0 0.0 3.5 0.0 4.0 0.6 0.4 0.0 1.6 0.0 21.5 0.0 1.2 0.1 0.0 0.0 0.3 0.0 0.0 27.5 2132.8 0.1 0.0 0.0 0.0 71.2 38.0 0.0 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.3 0.0 0.0 706.8 0.0 0.0 0.0 23.6 0.1 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.5 SAAL1 FLJ41463 ENSG00000166788 "Serum amyloid A like 1" Q96ER3 11 18069935-18106087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039003, HPA039004" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA039003: AB_2676303, HPA039004: AB_10673602" "unprognostic (1.13e-1)" "unprognostic (3.00e-1)" "unprognostic (4.35e-1)" "unprognostic (2.37e-2)" "unprognostic (1.88e-1)" "unprognostic (5.76e-2)" "unprognostic (4.10e-3)" "unprognostic (1.53e-2)" "unprognostic (4.75e-2)" "unprognostic (7.26e-2)" "unprognostic (3.36e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.78e-5)" "unprognostic (2.86e-1)" "unprognostic (1.39e-1)" "unprognostic (3.72e-1)" "unprognostic (1.87e-1)" 6.0 5.3 4.9 8.2 4.8 19.1 10.0 5.6 6.1 6.2 4.3 9.6 8.0 7.5 7.7 6.6 5.6 4.8 6.5 4.6 5.0 5.4 8.3 4.9 14.6 4.8 5.3 8.2 8.1 5.4 5.2 7.0 4.9 6.0 11.9 8.2 5.6 5.8 5.8 5.7 6.7 9.6 4.8 7.5 6.7 12.8 5.1 13.7 6.1 7.2 15.6 7.8 6.1 5.7 27.1 41.5 29.5 40.5 19.5 21.8 24.6 29.9 20.4 44.8 52.8 57.8 10.1 73.0 15.5 16.9 62.3 34.9 56.9 48.5 62.6 32.5 57.4 33.6 24.9 35.0 15.9 57.1 28.6 15.2 22.2 28.7 42.9 16.8 38.5 62.8 50.5 23.9 37.2 36.2 66.7 54.2 38.5 41.7 39.0 65.7 51.8 25.4 25.7 31.4 36.4 34.3 26.9 28.4 36.4 37.1 18.2 25.9 15.8 51.0 35.0 29.4 43.2 11.6 37.7 80.6 21.2 45.2 47.5 11.1 12.9 4.3 14.0 15.4 13.5 16.5 16.2 12.3 22.3 11.7 12.3 13.3 0.6 10.4 14.6 11.4 20.9 10.8 4.9 4.8 5.6 6.1 4.6 5.0 4.8 5.3 4.9 4.8 5.1 5.7 7.6 0.0 10.8 7.5 15.9 4.6 7.8 16.0 9.6 9.0 7.2 6.9 8.5 2.8 7.4 1.8 2.1 22.0 13.6 6.3 5.9 9.6 21.9 4.4 8.0 8.7 28.1 11.1 8.5 10.2 23.1 8.0 4.6 4.2 14.0 15.3 5.7 4.6 16.1 0.0 9.5 10.7 8.2 10.9 7.3 3.5 8.1 7.7 5.4 6.5 10.7 6.5 4.1 15.1 11.7 6.6 7.5 7.9 17.3 3.8 6.9 7.7 6.0 8.5 6.6 6.1 10.5 41.5 24.9 8.3 5.4 10.4 9.9 10.1 15.1 6.1 SAMD1 ENSG00000141858 "Sterile alpha motif domain containing 1" 19 14087851-14091036 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041662, HPA049059" Uncertain Approved Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Cytosol Mitochondria "HPA041662: AB_2677605, HPA049059: AB_2680616" "unprognostic (2.93e-2)" "prognostic favorable (7.41e-4)" "unprognostic (8.43e-2)" "unprognostic (3.30e-1)" "unprognostic (1.56e-2)" "unprognostic (1.72e-2)" "prognostic unfavorable (1.96e-5)" "unprognostic (2.66e-1)" "unprognostic (9.92e-2)" "unprognostic (3.86e-3)" "unprognostic (9.26e-3)" "unprognostic (4.00e-1)" "prognostic unfavorable (7.98e-5)" "prognostic favorable (8.31e-4)" "unprognostic (1.68e-2)" "unprognostic (3.29e-2)" "unprognostic (2.45e-1)" 24.7 18.1 53.2 18.3 51.9 22.3 21.2 49.0 50.5 29.9 33.9 32.3 20.1 30.0 8.7 37.0 24.7 8.2 37.6 48.6 49.6 25.8 24.2 24.5 21.4 57.0 51.6 27.5 24.8 8.0 14.9 10.8 54.4 21.8 14.2 7.1 20.2 14.0 50.9 39.7 29.4 11.7 51.7 38.2 28.6 26.3 52.6 44.5 20.6 22.6 17.7 29.4 30.4 54.0 73.2 54.8 47.3 67.3 28.7 29.7 71.8 39.3 9.4 39.5 31.7 41.5 35.3 125.1 51.2 25.6 18.9 57.9 51.5 29.5 19.5 84.3 42.8 55.5 73.7 76.0 25.9 33.1 33.1 20.7 47.5 27.4 9.2 37.6 23.5 79.6 67.9 33.8 22.9 110.2 69.0 129.2 96.7 53.0 47.9 92.1 41.9 91.8 33.5 35.2 86.5 86.1 34.8 46.6 26.6 25.0 29.6 70.0 26.1 68.7 62.1 69.5 50.7 62.0 58.1 105.2 41.0 89.0 28.4 0.2 1.3 2.5 0.8 0.5 1.0 2.1 0.9 1.0 1.2 1.4 1.2 0.9 0.2 3.7 0.5 0.9 1.1 0.8 53.2 51.9 49.0 50.5 48.6 49.6 57.0 51.6 54.4 51.7 52.6 54.0 42.0 3.2 6.7 0.7 10.9 11.5 4.6 14.4 18.8 31.4 25.2 31.4 11.9 21.5 5.5 11.0 6.2 3.9 22.4 48.6 1.9 11.2 0.3 24.4 21.6 19.4 24.7 43.6 0.3 11.1 9.3 14.3 9.7 24.5 8.2 15.2 13.6 13.8 15.5 52.2 0.4 24.0 6.1 25.7 16.1 2.2 19.3 19.6 10.6 0.0 11.3 19.4 2.1 1.0 0.9 13.0 18.9 18.8 13.3 6.6 23.6 6.6 10.6 8.5 13.1 7.5 18.8 0.8 20.4 29.2 17.2 1.8 14.1 8.2 30.5 4.8 SAMD11 MGC45873 ENSG00000187634 "Sterile alpha motif domain containing 11" Q96NU1 1 923923-944575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Rod photoreceptor cells: 266.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 11 "NK-cells: 1.3" "Cell line enhanced" "Detected in many" "HEK 293: 87.6;HeLa: 142.1;SCLC-21H: 71.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030110 Approved Nucleoplasm,Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles" "HPA030110: " "unprognostic (9.96e-2)" "unprognostic (1.75e-1)" "unprognostic (4.11e-2)" "unprognostic (1.11e-2)" "unprognostic (1.20e-2)" "unprognostic (2.42e-1)" "unprognostic (9.28e-2)" "unprognostic (6.90e-2)" "unprognostic (3.11e-2)" "unprognostic (1.45e-1)" "unprognostic (1.62e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.35e-5)" "unprognostic (3.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.26e-2)" "unprognostic (1.18e-1)" 3.8 9.0 3.6 3.3 4.5 1.0 1.8 6.0 8.8 7.4 7.2 4.9 5.1 9.6 9.4 1.9 17.6 3.2 13.2 5.6 9.0 19.7 4.3 3.9 2.1 23.4 10.5 3.3 1.4 1.6 27.6 0.3 10.9 16.9 1.1 24.5 2.0 19.5 0.8 0.8 5.4 4.1 8.8 17.1 4.9 4.7 8.3 0.1 4.7 0.3 0.4 14.0 7.9 10.1 0.3 8.0 0.1 7.4 0.4 0.1 2.0 9.2 0.5 0.6 0.3 0.4 2.4 0.0 19.0 26.0 5.1 15.3 8.8 0.0 0.0 0.8 87.6 0.0 142.1 0.4 1.9 0.0 0.9 5.3 0.0 0.1 0.0 12.1 0.0 0.2 3.5 0.0 0.2 8.4 0.0 0.1 3.8 0.5 0.8 0.7 1.4 5.6 1.2 0.0 71.1 20.9 23.8 12.3 0.2 6.1 12.8 0.5 1.4 3.8 14.4 0.2 2.6 1.3 0.0 0.3 5.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 3.6 4.5 6.0 8.8 5.6 9.0 23.4 10.5 10.9 8.8 8.3 10.1 0.1 0.0 1.8 12.1 0.3 0.4 0.1 0.3 0.6 25.5 0.7 0.4 0.9 2.8 1.9 3.7 29.2 0.2 0.1 0.2 0.0 1.0 3.9 20.1 43.9 6.1 26.5 0.0 0.1 0.4 0.9 17.0 2.0 6.4 0.0 3.8 4.6 0.2 0.3 35.3 0.2 1.0 0.0 0.6 0.0 12.1 0.9 0.7 0.0 1.0 0.0 25.8 0.0 0.0 0.1 1.6 2.6 4.1 0.4 2.1 0.0 0.3 0.1 266.9 0.0 0.2 4.1 1.5 26.0 0.1 0.6 0.1 0.6 0.0 0.2 0.3 SAP30 ENSG00000164105 "Sin3A associated protein 30" O75446 4 173369969-173377532 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 77.2;Macrophages: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022627, HPA059012" Enhanced Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB022627: , HPA059012: AB_2683880" "unprognostic (1.53e-1)" "unprognostic (3.67e-2)" "unprognostic (3.26e-1)" "unprognostic (1.39e-1)" "unprognostic (5.83e-2)" "unprognostic (8.71e-2)" "prognostic unfavorable (1.24e-6)" "unprognostic (4.95e-2)" "unprognostic (7.23e-2)" "unprognostic (3.93e-2)" "unprognostic (4.48e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (3.97e-1)" "unprognostic (5.70e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" 17.4 12.9 17.4 13.3 19.7 23.4 12.8 18.4 21.6 13.9 16.1 25.6 9.5 13.2 9.6 9.9 16.9 8.6 20.4 17.0 18.2 6.2 9.0 12.8 8.0 19.3 18.2 14.6 7.3 4.5 8.1 7.1 19.2 11.4 7.0 16.3 11.6 9.7 10.5 8.5 12.5 12.4 18.7 15.7 18.4 24.7 17.6 10.3 10.6 7.4 6.6 19.5 12.6 25.3 49.0 16.3 46.3 45.2 29.0 17.9 10.1 22.5 19.3 24.7 30.4 7.0 19.4 43.9 10.3 26.3 31.1 12.0 37.8 19.1 18.9 49.6 35.9 58.7 39.6 20.0 27.5 34.0 35.9 29.8 9.2 21.1 21.2 34.7 29.3 31.5 30.8 181.4 32.2 20.9 48.4 38.0 20.5 21.7 31.3 38.9 16.5 31.6 15.1 7.8 37.5 79.1 31.8 31.9 14.9 11.8 13.5 20.0 29.1 17.6 23.9 41.4 52.8 101.5 39.1 41.8 56.8 81.6 51.2 0.4 1.3 0.0 0.6 0.7 0.2 0.1 0.3 0.4 1.0 0.2 0.0 0.2 0.5 0.0 0.4 0.0 0.4 0.2 17.4 19.7 18.4 21.6 17.0 18.2 19.3 18.2 19.2 18.7 17.6 25.3 42.1 0.0 2.3 11.1 7.2 51.7 6.6 3.9 16.5 26.2 25.5 29.3 28.9 4.3 3.7 7.3 22.9 2.1 22.5 4.8 0.0 2.2 23.1 23.6 34.3 27.3 19.7 20.2 12.5 3.5 9.3 19.9 19.4 7.4 7.0 13.5 14.6 9.0 9.3 25.2 14.6 10.5 0.0 77.2 13.8 6.2 10.2 77.0 33.8 3.7 15.2 57.7 2.1 7.1 15.4 2.4 2.7 6.4 17.6 8.6 6.4 6.2 9.9 46.3 52.6 12.5 31.7 63.7 15.2 16.1 53.0 1.2 27.0 12.3 11.1 4.1 SAPCD1 "C6orf26, NG23" ENSG00000228727 "Suppressor APC domain containing 1" Q5SSQ6 6 31762996-31764851 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.3" "Cell type enriched" "Detected in single" 15 "Respiratory ciliated cells: 1.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.4;U-2 OS: 1.1;U-937: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071699 Approved "Vesicles,Cell Junctions" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "Cell Junctions" "HPA071699: AB_2686433" "unprognostic (9.25e-4)" "unprognostic (1.32e-1)" "unprognostic (3.41e-2)" "unprognostic (3.28e-1)" "unprognostic (9.34e-2)" "unprognostic (8.02e-4)" "unprognostic (1.63e-2)" "unprognostic (3.80e-2)" "unprognostic (2.01e-1)" "unprognostic (8.16e-3)" "unprognostic (1.56e-2)" "unprognostic (2.25e-1)" "unprognostic (8.15e-10)" "unprognostic (2.65e-2)" "unprognostic (4.45e-1)" "unprognostic (3.57e-1)" "unprognostic (7.98e-5)" 2.7 1.1 0.4 0.0 0.4 0.2 2.5 0.5 0.9 2.4 0.4 3.7 0.0 2.5 0.1 2.5 3.9 0.0 1.2 0.4 0.3 7.4 3.1 2.0 0.6 0.4 0.5 3.8 2.1 0.0 6.1 0.1 0.4 6.0 0.2 1.2 2.3 0.1 1.0 28.3 3.9 0.1 0.4 4.8 2.6 3.6 0.4 0.2 2.2 0.0 0.1 2.5 2.2 0.4 0.4 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.0 0.5 0.0 0.3 0.2 0.0 0.1 0.5 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.7 0.4 0.2 0.2 0.2 0.5 0.0 0.1 0.7 1.4 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.2 0.2 0.1 0.0 0.3 0.4 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.7 0.1 0.4 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.4 0.3 0.4 0.5 0.4 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SAR1A "SAR1, Sara, SARA1" ENSG00000079332 "Secretion associated Ras related GTPase 1A" Q9NR31 10 70147289-70170523 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006923, CAB022545, HPA048368" Supported Supported "Endoplasmic reticulum" NA NA 660000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "CAB022545: , HPA006923: AB_1856577, HPA048368: AB_2680373" "unprognostic (3.77e-2)" "unprognostic (7.13e-2)" "unprognostic (3.08e-3)" "unprognostic (3.13e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (7.00e-5)" "prognostic unfavorable (4.04e-4)" "unprognostic (1.60e-2)" "unprognostic (1.00e-1)" "unprognostic (1.02e-2)" "unprognostic (4.06e-2)" "unprognostic (2.06e-1)" "unprognostic (2.38e-3)" "unprognostic (1.76e-1)" "unprognostic (4.80e-2)" "unprognostic (1.10e-2)" "unprognostic (7.13e-2)" 77.1 52.8 41.8 38.4 43.5 163.2 48.1 45.1 45.7 43.1 53.3 39.1 26.6 41.0 47.0 41.4 37.3 35.0 44.8 43.8 48.3 43.3 70.2 51.4 36.7 42.8 44.9 41.0 33.9 44.2 37.9 76.0 44.0 38.9 35.5 42.0 39.9 38.9 51.1 38.5 34.5 49.7 47.3 40.7 37.9 23.5 48.4 33.2 39.8 56.3 38.4 45.8 36.2 52.1 85.8 56.3 75.7 131.9 246.1 143.1 61.1 128.3 154.4 115.6 140.0 169.7 78.2 74.4 67.1 153.7 52.8 96.6 94.5 75.9 111.6 103.9 44.3 54.1 65.8 82.5 112.4 86.7 56.6 155.9 68.4 76.4 133.2 119.0 63.8 55.9 68.7 105.9 110.0 60.0 73.8 72.6 65.2 55.6 141.3 70.8 84.4 42.5 88.7 69.7 42.6 73.8 98.0 134.6 72.2 66.8 65.8 59.7 88.6 63.7 94.3 92.2 91.3 72.3 141.3 114.0 84.9 111.7 48.7 75.5 63.5 74.0 88.0 80.9 94.8 47.7 68.5 85.9 58.5 38.6 65.7 88.7 67.9 103.3 72.9 44.8 53.2 95.9 41.8 43.5 45.1 45.7 43.8 48.3 42.8 44.9 44.0 47.3 48.4 52.1 88.4 128.2 110.2 6.8 53.5 235.7 138.0 120.2 25.0 38.6 99.2 62.4 74.7 57.2 105.3 49.7 33.3 120.6 109.8 51.6 54.8 78.4 3.0 52.3 85.8 85.2 42.7 46.1 21.2 77.3 199.0 127.8 23.9 89.7 53.2 46.3 69.7 114.1 101.0 26.9 22.2 72.1 65.1 51.2 208.9 5.6 54.7 68.1 113.8 21.5 58.4 61.9 75.2 16.1 26.4 78.8 56.2 58.6 97.7 141.4 59.1 95.9 67.1 33.4 78.9 73.7 158.8 64.1 51.8 37.2 248.8 238.9 86.3 45.2 53.2 175.2 SARAF "MGC8721, TMEM66" ENSG00000133872 "Store-operated calcium entry associated regulatory factor" Q96BY9 8 30063003-30083208 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040400 Supported "Endoplasmic reticulum,Rods & Rings" NA NA 41000 "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum" "Rods & Rings" "HPA040400: AB_2676962" "unprognostic (1.11e-1)" "unprognostic (4.78e-2)" "unprognostic (4.27e-3)" "unprognostic (1.38e-3)" "unprognostic (7.86e-3)" "unprognostic (1.91e-1)" "unprognostic (2.32e-1)" "prognostic favorable (5.28e-4)" "unprognostic (1.98e-1)" "unprognostic (1.74e-2)" "unprognostic (8.03e-2)" "unprognostic (6.70e-3)" "unprognostic (1.06e-2)" "unprognostic (5.09e-2)" "unprognostic (3.88e-2)" "unprognostic (3.87e-2)" "unprognostic (2.18e-1)" 139.9 294.5 208.6 169.1 228.0 253.0 169.9 187.2 246.6 153.8 196.2 143.0 123.9 152.1 408.6 91.0 205.9 182.1 151.8 234.6 308.8 205.2 302.3 167.5 218.9 214.0 258.8 255.7 231.4 236.5 138.9 309.2 247.6 228.2 143.5 219.1 212.9 172.7 111.1 70.8 140.5 139.1 219.5 159.0 161.1 104.3 290.5 243.4 245.4 129.0 186.5 141.0 64.0 218.5 119.9 112.4 147.9 79.9 209.3 149.8 69.7 139.2 247.0 128.5 173.7 72.2 139.9 80.9 183.5 156.0 134.7 97.7 100.8 112.4 146.9 33.6 49.5 112.2 87.3 119.2 189.6 48.8 130.6 175.2 260.0 121.6 125.5 257.4 192.0 150.7 128.4 191.2 142.9 74.2 128.4 88.8 96.0 253.6 61.3 98.7 88.4 107.4 220.3 100.4 48.6 162.5 140.6 160.5 208.2 115.7 112.2 93.3 144.0 89.6 230.5 35.0 56.5 103.4 110.6 81.0 215.8 118.4 146.5 964.6 252.9 443.1 321.2 253.2 364.8 233.1 473.0 377.9 247.0 302.4 776.2 543.6 478.1 258.8 335.3 212.0 483.8 920.3 208.6 228.0 187.2 246.6 234.6 308.8 214.0 258.8 247.6 219.5 290.5 218.5 179.8 169.9 147.6 79.0 458.5 0.0 331.6 0.0 154.8 291.5 247.8 166.2 135.4 261.7 82.3 211.5 123.0 235.9 566.8 142.2 127.2 387.5 629.8 235.9 114.8 170.8 115.3 145.4 128.0 358.9 254.5 181.7 170.7 133.6 223.3 325.7 240.2 273.4 292.0 139.7 157.8 122.0 0.0 448.6 0.0 908.1 218.7 387.9 0.0 60.9 298.5 317.2 358.4 82.9 111.7 250.1 137.0 294.2 505.1 280.7 252.6 289.7 212.1 252.5 177.5 203.7 177.1 194.7 133.9 133.4 0.0 276.9 794.4 167.8 115.9 310.6 SATB1 ENSG00000182568 "SATB homeobox 1" Q01826 3 18345377-18445588 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 374.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 180.2;Inhibitory neurons: 283.4;Oligodendrocyte precursor cells: 168.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 113.7" "Group enriched" "Detected in all" 4 "NK-cells: 63.4;T-cells: 113.7" "Cell line enhanced" "Detected in many" "HDLM-2: 455.3;JURKAT: 213.3;MOLT-4: 107.7;REH: 126.5;THP-1: 192.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051769, CAB056144, HPA070534" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies" "CAB056144: AB_10584780, HPA051769: AB_2681600, HPA070534: " "unprognostic (2.16e-1)" "unprognostic (3.99e-1)" "unprognostic (7.13e-2)" "unprognostic (3.58e-1)" "unprognostic (9.15e-2)" "unprognostic (4.22e-3)" "unprognostic (2.16e-1)" "unprognostic (1.62e-3)" "unprognostic (2.90e-2)" "unprognostic (6.14e-2)" "prognostic favorable (8.97e-4)" "unprognostic (1.66e-1)" "prognostic favorable (1.96e-7)" "unprognostic (1.92e-2)" "unprognostic (2.18e-1)" "unprognostic (2.79e-2)" "unprognostic (1.47e-3)" 16.1 10.3 13.4 28.8 19.1 42.8 13.2 0.8 32.2 11.4 2.6 29.9 16.0 13.6 24.0 12.2 17.9 17.6 26.0 23.4 0.4 10.8 15.4 15.7 38.1 0.3 6.1 13.8 28.8 32.4 22.5 4.9 0.0 22.5 18.5 29.8 44.0 25.9 89.5 21.4 21.0 11.8 1.4 27.4 18.5 6.7 0.9 374.2 24.5 49.0 27.8 24.6 12.3 11.0 2.1 0.0 12.7 0.0 17.2 16.6 1.4 3.4 12.3 2.9 9.8 0.5 22.9 4.7 0.4 4.1 1.0 0.2 46.4 5.4 5.9 455.3 28.0 0.1 1.1 0.0 2.5 26.7 3.8 7.4 4.0 0.1 0.6 35.1 3.3 213.3 0.6 24.3 2.2 0.4 107.7 33.9 18.5 1.5 1.5 126.5 6.2 4.9 4.8 15.7 5.9 34.5 0.0 3.9 0.3 10.0 98.5 192.7 1.7 12.6 7.9 5.9 3.7 1.3 0.4 10.0 10.3 101.3 5.7 21.1 1.9 4.6 44.2 2.0 78.6 1.6 29.9 23.0 3.5 13.0 113.7 69.5 4.1 63.4 1.1 4.0 6.0 26.6 13.4 19.1 0.8 32.2 23.4 0.4 0.3 6.1 0.0 1.4 0.9 11.0 19.3 25.6 29.6 48.3 44.6 14.3 12.3 10.9 12.0 12.1 33.2 18.0 70.0 22.8 15.0 31.3 87.6 0.5 71.1 11.0 1.9 16.9 8.2 31.6 15.3 17.0 32.4 22.5 180.2 12.5 0.2 16.4 8.6 11.6 23.4 20.6 35.0 20.9 9.3 0.0 283.4 30.8 4.1 41.5 36.4 4.3 8.4 45.5 10.6 41.2 23.0 15.5 56.7 168.9 28.8 10.5 23.6 8.2 20.6 21.7 24.6 9.1 50.9 63.1 6.6 8.3 10.2 3.2 9.3 20.5 22.0 0.3 84.0 16.8 25.7 19.7 SAXO2 "DKFZp666G057, FAM154B" ENSG00000188659 "Stabilizer of axonemal microtubules 2" Q658L1 15 82262810-82284930 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 59.9;testis: 21.6" "Group enriched" "Detected in many" 4 "Early spermatids: 90.9;Endometrial ciliated cells: 71.5;Late spermatids: 175.4;Respiratory ciliated cells: 201.9;Spermatocytes: 57.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 10.5;K-562: 10.0;SCLC-21H: 7.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040487, HPA040833" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Golgi apparatus" "HPA040487: AB_10796457, HPA040833: AB_10796561" "unprognostic (3.03e-2)" "unprognostic (3.59e-1)" "unprognostic (1.91e-2)" "unprognostic (1.19e-2)" "unprognostic (1.98e-1)" "unprognostic (2.28e-1)" "unprognostic (4.13e-1)" "unprognostic (4.69e-2)" "unprognostic (6.26e-2)" "unprognostic (3.11e-2)" "unprognostic (1.04e-3)" "unprognostic (1.97e-1)" "unprognostic (2.91e-1)" "unprognostic (2.90e-2)" "unprognostic (4.71e-2)" "unprognostic (6.20e-2)" "unprognostic (3.87e-2)" 0.9 1.1 2.1 0.3 2.2 0.6 3.2 2.3 2.7 2.3 8.3 1.3 0.7 2.2 17.9 0.6 59.9 1.0 1.3 2.5 2.3 2.7 0.9 8.0 1.2 3.2 5.0 1.7 1.6 4.7 4.9 0.4 2.4 2.6 2.0 6.9 2.8 1.2 1.3 2.1 1.6 0.6 3.1 1.2 2.5 21.6 2.5 2.6 3.5 0.8 1.6 1.3 1.0 3.7 1.4 1.9 1.1 4.1 0.9 1.8 0.5 0.5 0.3 0.8 1.5 0.2 2.3 1.4 1.0 0.0 2.2 10.5 1.8 1.6 1.8 1.0 6.8 0.5 3.4 0.0 0.1 0.3 0.4 1.2 2.2 1.4 1.2 2.3 1.7 2.9 10.0 0.7 1.0 1.0 0.5 0.0 2.7 0.5 0.8 1.4 0.5 0.9 0.8 0.9 7.8 1.2 1.1 0.0 1.5 0.6 4.0 0.4 0.2 2.0 1.1 4.2 0.8 2.1 2.6 0.9 1.9 0.5 1.3 0.0 0.0 3.0 0.5 0.0 0.8 1.3 0.2 1.5 0.1 3.3 0.9 0.4 0.0 2.0 0.1 0.8 0.0 0.3 2.1 2.2 2.3 2.7 2.5 2.3 3.2 5.0 2.4 3.1 2.5 3.7 1.8 0.0 2.7 9.1 1.5 0.0 2.0 0.0 2.8 2.7 4.5 4.1 2.7 1.5 24.1 3.7 4.2 0.5 0.9 0.1 1.9 0.7 90.9 71.5 1.5 0.9 2.4 0.8 21.1 0.5 0.4 1.5 10.2 2.0 1.3 3.7 0.4 0.3 0.1 0.0 16.4 1.9 0.0 0.6 0.0 175.4 2.5 0.5 0.0 3.7 0.0 3.7 0.0 9.0 8.0 0.3 0.1 2.2 1.9 1.5 0.3 4.6 201.9 5.0 6.6 1.0 1.0 57.7 12.7 0.9 0.0 0.3 0.7 3.0 0.5 1.6 SBSN "HLAR698, UNQ698" ENSG00000189001 Suprabasin Q6UWP8 19 35523367-35528351 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1056.2;skin 1: 2444.7;vagina: 756.5" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 1017.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 355.2;melanoma: 153.1" "Group enriched" "Detected in some" 5 "basal ganglia: 3.9;cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.2;ASC TERT1: 107.5;HSkMC: 146.1;U-2197: 51.6;U-87 MG: 119.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062568, HPA067734" Enhanced Approved Vesicles "Secreted - unknown location" NA NA 89000000 "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA062568: AB_2684794, HPA067734: AB_2685894" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-2)" "unprognostic (1.23e-3)" "unprognostic (3.45e-3)" "unprognostic (2.56e-1)" "unprognostic (4.83e-4)" "unprognostic (4.31e-4)" "unprognostic (6.97e-2)" "unprognostic (9.08e-14)" "unprognostic (6.37e-2)" "unprognostic (6.51e-3)" "unprognostic (2.09e-1)" "unprognostic (1.36e-3)" 2.9 0.6 0.5 0.1 3.9 0.7 94.3 0.4 1.3 465.7 0.3 1.0 0.0 0.5 0.0 1056.2 0.2 0.3 1.4 0.5 0.4 0.4 1.7 0.9 0.0 0.5 0.4 0.7 1.5 0.0 0.9 0.3 0.5 0.5 0.0 0.0 351.8 0.0 13.1 2444.7 0.7 0.2 0.4 0.5 1.1 1.0 0.5 6.5 0.7 0.0 168.9 1.1 756.5 0.4 0.1 0.1 0.0 0.1 62.2 107.5 0.1 5.1 7.2 2.4 0.9 0.0 0.1 0.1 1.2 4.8 1.7 0.3 0.0 1.8 1.0 0.1 0.2 0.0 0.1 0.0 0.6 0.0 0.1 146.1 8.2 30.0 7.1 2.1 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 1.4 0.3 0.2 0.0 0.4 18.4 3.8 51.6 1.4 0.5 0.3 0.0 119.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.9 0.4 1.3 0.5 0.4 0.5 0.4 0.5 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 89.3 0.1 0.6 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1.4 0.8 1.8 0.0 0.0 0.2 0.6 0.2 3.1 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 25.2 4.0 0.0 0.2 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 1.0 0.2 0.2 13.4 1017.6 0.3 0.7 0.0 0.0 0.4 SBSPON "C8orf84, RPESP" ENSG00000164764 "Somatomedin B and thrombospondin type 1 domain containing" Q8IVN8 8 73064543-73124088 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 36.5;Collecting duct cells: 42.3;Muller glia cells: 48.5;Peritubular cells: 26.7;Smooth muscle cells: 28.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "medulla oblongata: 7.5;pons: 6.3;spinal cord: 7.7;white matter: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ: 9.5;RPTEC TERT1: 16.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA029595 Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 40000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA029595: AB_10600763" "prognostic favorable (7.18e-4)" "unprognostic (5.08e-3)" "unprognostic (3.24e-1)" "unprognostic (4.41e-2)" "unprognostic (1.75e-1)" "unprognostic (2.31e-1)" "unprognostic (2.78e-2)" "unprognostic (8.65e-2)" "unprognostic (2.92e-1)" "unprognostic (1.46e-1)" "unprognostic (9.54e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (6.14e-2)" "unprognostic (3.54e-1)" "unprognostic (2.12e-2)" "unprognostic (6.25e-2)" 6.4 3.0 0.4 1.4 0.5 0.3 3.4 1.2 0.6 5.2 0.6 4.7 0.9 4.4 4.5 9.5 8.2 1.3 2.3 0.8 0.8 8.3 0.6 3.9 1.5 7.5 0.9 3.3 1.2 0.1 1.6 9.4 6.3 15.1 1.1 9.0 4.6 10.8 0.6 1.9 2.5 8.9 7.7 1.1 9.6 2.6 0.4 0.2 2.5 1.4 0.2 17.9 4.7 16.7 0.2 0.2 0.4 0.5 0.0 0.0 1.3 9.5 0.0 0.0 0.0 0.1 0.2 0.4 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.4 0.3 0.4 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.3 0.0 0.0 0.4 0.3 0.9 0.5 0.2 0.2 0.1 0.0 16.9 0.1 0.5 0.5 1.0 0.4 0.1 3.1 0.2 0.1 0.5 0.1 1.5 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.5 1.2 0.6 0.8 0.8 7.5 0.9 6.3 7.7 0.4 16.7 0.6 9.6 0.0 1.0 0.2 1.3 6.9 0.0 36.5 2.4 5.8 11.6 3.8 4.3 0.0 42.3 2.1 0.2 1.0 0.5 1.9 1.3 10.3 7.2 1.4 1.7 0.0 0.0 0.5 0.0 0.4 13.2 10.7 14.9 0.0 0.2 1.4 0.2 0.4 0.0 0.4 0.2 0.0 0.0 0.4 3.2 12.2 0.4 3.6 0.0 0.0 48.5 0.0 1.0 0.2 0.6 0.0 26.7 0.0 1.8 0.0 3.6 0.0 2.2 6.6 0.9 28.7 11.4 4.4 0.6 1.3 0.4 0.5 0.2 0.1 0.5 SCAF8 "KIAA1116, RBM16" ENSG00000213079 "SR-related CTD associated factor 8" Q9UPN6 6 154733378-154834244 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 105.4;Inhibitory neurons: 114.2;Microglial cells: 119.9;Oligodendrocyte precursor cells: 121.2;Oligodendrocytes: 145.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035601, HPA035602" Enhanced Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA035601: AB_2674698, HPA035602: AB_10673220" "unprognostic (4.60e-3)" "unprognostic (3.67e-2)" "unprognostic (7.90e-3)" "unprognostic (2.50e-2)" "unprognostic (6.18e-2)" "unprognostic (1.13e-1)" "unprognostic (1.01e-2)" "unprognostic (3.41e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (6.61e-4)" "unprognostic (3.65e-1)" "unprognostic (2.08e-1)" "unprognostic (9.08e-2)" "unprognostic (2.66e-1)" "unprognostic (1.52e-1)" "unprognostic (2.42e-1)" "unprognostic (1.11e-1)" 19.2 11.8 7.9 15.6 10.3 37.2 18.9 17.8 9.9 18.2 2.7 14.9 12.7 22.1 16.4 13.2 17.4 13.6 14.8 6.9 8.5 16.6 15.4 16.2 22.6 7.3 8.5 27.0 14.9 21.3 10.2 18.9 6.2 16.9 17.6 23.2 15.6 15.6 18.7 18.3 14.3 20.3 6.8 19.1 15.2 23.5 8.7 26.8 21.3 19.1 20.8 15.3 14.7 10.4 16.2 15.3 44.6 27.1 29.3 29.8 27.2 25.7 35.8 33.1 33.4 24.2 16.0 49.7 20.4 29.6 29.4 21.1 39.5 33.8 44.2 21.7 19.7 44.6 16.0 29.8 33.8 41.7 28.8 32.3 35.0 29.0 45.0 25.7 28.6 21.6 52.6 29.4 30.8 29.1 44.6 28.2 31.0 24.4 11.3 42.3 24.4 27.1 28.1 29.0 27.4 32.3 26.7 34.7 19.9 32.1 22.8 47.8 26.3 18.8 23.0 24.6 26.2 27.2 21.7 54.0 23.4 25.6 30.0 0.6 1.5 1.8 2.8 2.0 2.8 2.4 3.0 2.9 1.7 2.6 3.0 2.7 1.9 3.1 3.8 1.6 4.0 1.4 7.9 10.3 17.8 9.9 6.9 8.5 7.3 8.5 6.2 6.8 8.7 10.4 23.1 25.6 18.1 89.8 22.6 12.6 12.2 11.9 17.6 19.5 14.6 12.4 33.9 7.2 11.7 12.9 25.0 11.1 23.2 15.8 1.9 11.3 3.6 18.8 25.4 16.6 13.1 18.7 105.4 11.8 8.8 17.5 23.0 25.0 34.2 29.3 18.5 11.6 13.3 13.5 114.2 14.1 6.1 20.8 9.7 5.4 16.4 16.6 10.6 119.9 13.5 16.1 8.2 121.2 145.8 13.6 11.8 12.4 13.7 13.7 11.7 6.5 15.8 21.4 26.3 24.5 16.3 21.4 21.2 14.8 10.7 10.7 19.2 19.5 16.1 15.4 SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted intracellular proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.6" "Cell type enhanced" "Detected in many" "Adipocytes: 65.9;Endothelial cells: 51.3;Hepatic stellate cells: 62.4;Langerhans cells: 37.7;Microglial cells: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 12.1;REH: 11.5;TIME: 37.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 2000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA035108: AB_10670289, HPA072936: AB_2686559" "unprognostic (1.94e-1)" "unprognostic (2.84e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (6.39e-2)" 15.2 5.0 1.5 3.1 1.8 0.4 12.7 1.4 3.4 5.6 1.4 5.2 0.0 6.0 0.9 2.7 6.5 2.2 11.8 1.6 1.8 7.5 7.5 16.3 2.1 2.7 1.7 2.6 3.1 0.1 3.8 4.3 2.2 4.6 1.2 0.2 4.2 0.0 5.3 3.1 5.4 1.2 1.7 25.6 4.2 1.6 1.7 0.5 18.8 1.9 1.0 5.6 4.6 2.8 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.3 12.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 11.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 37.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 1.8 1.4 3.4 1.6 1.8 2.7 1.7 2.2 1.7 1.7 2.8 65.9 22.4 17.6 6.5 0.6 3.4 0.4 0.7 1.2 1.2 0.8 0.9 3.5 0.0 2.9 3.7 4.2 0.4 2.0 4.9 1.9 0.4 0.3 0.5 0.9 51.3 0.0 3.4 5.4 0.2 0.2 2.5 4.1 1.1 3.8 0.3 62.4 2.3 9.0 0.0 3.5 4.4 0.0 15.7 37.7 0.4 1.2 10.1 3.6 26.2 4.8 0.7 0.0 0.5 1.1 0.3 1.2 1.2 0.0 0.7 3.0 0.2 3.0 2.0 0.0 2.1 3.0 0.5 0.6 0.3 2.7 1.2 1.0 1.3 2.2 0.8 SCFD1 "C14orf163, KIAA0917, RA410, SLY1, STXBP1L2" ENSG00000092108 "Sec1 family domain containing 1" Q8WVM8 14 30622291-30737694 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003579 Approved NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" "HPA003579: AB_1079872" "unprognostic (2.33e-1)" "unprognostic (1.04e-1)" "unprognostic (1.07e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (1.24e-2)" "unprognostic (1.21e-1)" "unprognostic (3.21e-2)" "unprognostic (3.07e-2)" "unprognostic (8.35e-2)" "unprognostic (2.65e-1)" "unprognostic (7.52e-3)" "unprognostic (1.05e-1)" "unprognostic (3.08e-1)" "unprognostic (3.05e-1)" "unprognostic (6.32e-2)" 23.2 29.3 11.8 22.3 12.4 9.9 29.2 12.3 12.6 34.0 13.0 27.6 22.2 21.8 40.8 29.7 21.7 19.6 29.6 11.9 12.4 32.5 35.1 22.5 26.2 11.8 12.1 23.6 46.4 41.8 29.3 27.8 11.8 27.7 29.8 14.9 52.3 24.0 24.6 19.5 23.8 22.9 11.5 19.0 28.0 26.6 11.6 25.6 44.3 29.3 29.1 30.0 20.8 12.0 71.7 26.0 37.8 22.9 64.1 67.0 53.4 57.0 68.4 69.5 83.5 42.2 58.9 36.9 24.2 79.7 38.8 44.5 41.3 46.5 80.0 53.2 22.2 30.7 28.6 149.5 77.9 50.2 32.4 49.1 39.1 48.9 78.1 58.5 45.5 26.5 42.6 68.0 74.7 66.8 30.7 27.8 40.7 83.9 45.1 30.2 42.1 42.2 70.7 45.6 35.9 33.0 58.7 54.4 53.6 42.9 70.5 35.3 48.1 41.9 44.0 43.0 45.3 45.3 40.8 49.4 26.9 36.7 52.9 26.8 17.2 20.2 14.0 23.2 17.8 20.1 16.2 17.3 23.7 14.7 15.2 14.1 3.0 23.1 27.8 16.9 24.4 16.1 11.8 12.4 12.3 12.6 11.9 12.4 11.8 12.1 11.8 11.5 11.6 12.0 33.0 51.3 31.3 67.9 47.7 25.0 55.2 55.1 18.2 35.0 26.9 27.1 35.3 18.6 50.8 25.8 43.8 61.9 51.3 31.8 64.6 49.2 29.3 34.9 51.6 32.3 47.2 24.2 123.0 50.6 61.0 47.9 20.9 34.2 53.7 32.1 24.3 20.6 44.9 30.3 112.8 44.9 36.7 27.7 33.4 16.6 38.5 35.5 37.4 90.9 66.9 31.1 62.8 112.6 106.6 41.2 23.5 40.3 70.9 42.3 28.8 40.9 52.1 39.9 13.1 53.7 49.0 71.8 53.5 20.5 24.4 83.0 41.4 47.8 30.0 43.5 SCG2 "CHGC, SgII, SN" ENSG00000171951 "Secretogranin II" P13521 2 223596940-223602361 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 360.1;brain: 426.2;pituitary gland: 269.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 212.4;Enteroendocrine cells: 283.4;Inhibitory neurons: 109.9;Ionocytes: 138.4" "Group enriched" "Detected in many" 8 "glioma: 70.0;pancreatic cancer: 52.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 53.3;HSkMC: 45.9;hTERT-RPE1: 46.5;SCLC-21H: 47.6;SH-SY5Y: 20.7;WM-115: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011893, HPA075062" Enhanced Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 330000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" Vesicles "HPA011893: AB_1856656, HPA075062: AB_2732277" "unprognostic (2.93e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-3)" "unprognostic (6.82e-4)" "unprognostic (2.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.77e-3)" "unprognostic (6.73e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "prognostic favorable (5.58e-4)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.01e-10)" "unprognostic (2.47e-3)" "unprognostic (4.02e-1)" "unprognostic (1.57e-2)" "unprognostic (1.90e-3)" 9.2 360.1 49.2 30.2 78.4 0.4 0.5 17.1 54.7 1.5 2.2 10.6 47.7 3.5 0.4 0.6 0.2 4.0 1.7 21.7 426.2 0.6 0.2 3.3 0.4 118.3 195.4 6.1 28.3 0.5 269.0 1.1 250.9 3.5 13.0 40.6 0.3 1.2 0.3 1.0 21.3 12.8 77.4 0.2 17.9 0.2 130.7 0.1 6.4 0.8 0.1 0.8 1.3 30.3 0.0 3.1 10.3 8.5 2.3 53.3 0.2 0.5 2.0 4.0 10.1 0.4 1.0 0.0 0.9 0.7 6.2 0.2 0.2 0.0 5.0 0.1 0.5 0.0 0.6 0.0 0.5 0.7 4.6 45.9 0.2 5.8 2.0 46.5 0.0 0.0 0.2 0.4 5.1 0.3 0.0 0.2 7.3 0.1 0.2 0.0 0.3 0.3 0.9 0.1 47.6 20.7 0.0 0.5 2.5 1.6 0.0 0.1 0.1 5.4 2.2 0.2 3.6 0.1 0.0 0.3 1.6 0.1 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.2 78.4 17.1 54.7 21.7 426.2 118.3 195.4 250.9 77.4 130.7 30.3 0.0 6.4 0.0 12.7 0.0 0.0 0.4 2.8 0.0 212.4 0.0 0.0 0.1 0.0 1.3 0.0 2.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.2 6.7 283.4 0.0 27.7 0.2 0.0 2.3 0.0 0.1 0.0 0.0 0.7 0.0 0.1 8.4 109.9 14.7 138.4 0.3 0.3 0.0 0.6 0.0 1.8 3.7 0.0 11.6 0.0 34.2 8.2 14.8 6.2 0.4 0.0 2.1 0.1 0.1 0.7 14.6 0.0 1.8 1.7 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.5 0.8 SCG3 "FLJ90833, SgIII" ENSG00000104112 "Secretogranin III" Q8WXD2 15 51681492-51721026 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 133.5;choroid plexus: 40.1;pituitary gland: 39.4;retina: 56.8" "Group enriched" "Detected in many" 4 "Astrocytes: 79.3;Bipolar cells: 120.4;Cone photoreceptor cells: 102.2;Enteroendocrine cells: 148.4;Excitatory neurons: 46.2;Horizontal cells: 148.0;Inhibitory neurons: 64.0;Ionocytes: 38.7;Oligodendrocyte precursor cells: 63.3;Rod photoreceptor cells: 93.3" "Group enriched" "Detected in many" 7 "glioma: 41.0;pancreatic cancer: 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "NTERA-2: 50.5;SCLC-21H: 121.2;SH-SY5Y: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006880, CAB033274, HPA053715" Enhanced Supported Supported Vesicles "Secreted in brain" NA NA 3100000 "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" Vesicles "CAB033274: AB_2302033, HPA006880: AB_1079898, HPA053715: AB_2682239" "unprognostic (1.38e-2)" "unprognostic (2.42e-1)" "unprognostic (1.40e-1)" "unprognostic (5.24e-5)" "unprognostic (1.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.74e-1)" "unprognostic (9.93e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.71e-2)" "unprognostic (8.17e-2)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (2.78e-1)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" 0.5 16.7 71.0 1.1 87.0 0.6 0.5 85.8 133.5 0.1 40.1 1.8 2.3 0.2 0.3 0.3 0.3 0.2 0.2 88.2 112.7 0.2 0.2 0.6 0.4 68.7 75.8 0.1 15.6 0.2 39.4 0.1 68.9 0.3 2.0 56.8 0.2 0.0 0.1 0.6 2.0 0.5 71.9 0.2 9.9 2.6 79.8 0.5 1.0 0.0 0.2 0.2 0.2 71.6 0.2 0.1 4.8 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.2 0.3 0.5 0.0 0.6 0.4 0.1 0.0 0.1 0.1 0.5 0.1 0.3 0.1 0.0 0.3 3.0 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.8 0.0 0.3 0.1 0.1 50.5 0.1 0.2 0.3 0.1 0.4 0.0 0.5 121.2 57.5 0.2 0.4 0.2 15.5 0.1 3.8 0.1 0.3 0.7 0.2 0.2 0.4 0.2 0.4 0.7 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 71.0 87.0 85.8 133.5 88.2 112.7 68.7 75.8 68.9 71.9 79.8 71.6 0.2 0.0 0.0 79.3 0.0 0.3 0.0 0.3 0.0 120.4 0.0 0.1 0.2 0.0 0.1 0.0 102.2 0.0 0.0 0.2 1.9 0.4 20.0 0.0 0.0 4.3 148.4 0.0 46.2 1.0 0.1 4.1 0.0 0.0 0.0 0.0 1.8 0.0 0.4 148.0 64.0 3.4 38.7 0.0 0.3 11.3 0.0 0.1 1.8 7.5 6.7 19.2 0.0 63.3 8.9 5.3 0.0 0.4 0.0 0.4 0.1 0.0 0.8 93.3 0.0 0.4 0.2 13.8 5.8 0.0 0.0 0.0 0.0 0.2 0.3 0.3 SCG5 "7B2, SGNE1, SgV" ENSG00000166922 "Secretogranin V" P05408 15 32641676-32697098 "Predicted secreted proteins" Transport "Chaperone, Neuropeptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 133.0;pituitary gland: 402.7" "Cell type enriched" "Detected in many" 4 "Enteroendocrine cells: 470.8" "Group enriched" "Detected in many" 5 "glioma: 38.2;pancreatic cancer: 82.9;thyroid cancer: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 26.9;HSkMC: 33.5;NTERA-2: 15.3;SCLC-21H: 31.5;SH-SY5Y: 36.4;U-87 MG: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013136, HPA074618" Enhanced "Secreted to blood" NA NA 100000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA013136: AB_1856657, HPA074618: AB_2732262" "unprognostic (1.71e-1)" "unprognostic (9.87e-2)" "unprognostic (7.94e-2)" "unprognostic (1.30e-2)" "unprognostic (3.59e-3)" "prognostic unfavorable (9.64e-4)" "unprognostic (2.69e-1)" "unprognostic (1.27e-3)" "unprognostic (4.69e-2)" "unprognostic (1.97e-1)" "unprognostic (5.62e-3)" "unprognostic (3.92e-1)" "prognostic unfavorable (4.51e-9)" "unprognostic (3.57e-2)" "unprognostic (8.13e-2)" "unprognostic (3.08e-3)" "unprognostic (8.88e-2)" 1.7 61.1 54.0 3.3 62.0 0.3 3.7 52.2 100.4 1.0 77.3 7.9 17.9 5.3 42.5 0.5 3.4 5.5 1.3 58.9 75.1 0.9 3.6 3.8 1.3 56.5 48.3 3.2 133.0 73.7 402.7 0.3 58.7 5.0 9.8 26.7 0.2 0.9 0.2 1.3 5.6 6.7 57.7 0.5 37.8 5.3 56.3 0.3 5.8 0.1 0.3 2.6 2.7 58.9 0.5 0.2 0.1 0.2 0.6 4.5 0.1 4.2 0.4 0.4 0.4 0.1 0.0 0.5 1.9 0.4 1.7 1.2 0.5 0.2 1.2 0.7 0.3 0.6 0.0 0.1 26.9 0.2 0.7 33.5 0.1 0.8 0.4 0.9 0.7 1.0 0.3 0.6 0.8 0.0 0.3 0.3 15.3 0.1 0.8 0.1 0.4 0.6 0.4 0.0 31.5 36.4 0.2 0.0 0.2 0.4 0.1 0.4 0.0 5.2 3.8 0.3 0.5 0.6 2.3 0.4 47.2 1.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.0 62.0 52.2 100.4 58.9 75.1 56.5 48.3 58.7 57.7 56.3 58.9 0.2 0.0 0.5 20.2 0.3 0.6 0.2 6.2 0.0 51.0 0.5 16.5 0.4 0.0 3.9 0.0 2.1 0.2 0.1 1.1 0.0 0.6 52.1 3.7 19.3 1.1 470.8 0.0 82.8 78.3 0.3 17.9 23.0 0.6 2.5 51.4 0.4 11.9 6.0 50.5 97.8 14.5 97.6 0.6 0.8 80.0 2.1 1.6 3.6 20.6 0.6 15.6 0.0 52.3 79.7 22.9 1.1 7.9 0.3 1.4 0.5 0.0 0.5 32.6 0.0 0.3 34.2 39.2 2.9 0.1 0.3 0.3 0.3 51.8 2.4 1.0 SCGB1A1 "CC10, CC16, CCSP, UGB" ENSG00000149021 "Secretoglobin family 1A member 1" P11684 11 62405103-62423195 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Phospholipase A2 inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lung: 3079.0" "Cell type enriched" "Detected in some" 4 "Club cells: 43564.7" "Cancer enriched" "Detected in many" 8 "lung cancer: 215.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 71 "HaCaT: 1977.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025686, HPA031828" Enhanced "Secreted in other tissues" NA NA 13000000 "Cluster 19: Lung - Lung function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025686: , HPA031828: AB_2674061" "unprognostic (2.40e-3)" "unprognostic (1.55e-2)" "unprognostic (5.46e-2)" "unprognostic (2.70e-2)" "unprognostic (4.69e-3)" "unprognostic (2.12e-2)" "unprognostic (1.23e-2)" "unprognostic (2.31e-2)" "unprognostic (2.63e-2)" "unprognostic (1.63e-1)" "unprognostic (2.40e-2)" 1.1 2.0 0.6 0.9 0.7 0.1 0.3 1.3 1.1 0.6 0.3 0.2 0.4 0.2 0.7 11.0 334.2 0.2 0.6 0.5 0.6 0.2 0.4 3079.0 0.2 0.6 0.9 2.0 1.9 0.0 2.4 1.7 0.5 85.1 0.0 0.2 0.5 0.9 0.3 0.3 1.6 0.0 0.5 7.2 4.3 0.2 1.0 2.8 0.4 0.0 5.9 0.2 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.3 1977.1 0.0 0.3 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.3 27.9 0.0 0.0 0.0 0.0 0.1 0.2 0.8 0.0 1.1 0.0 0.0 0.6 1.4 0.4 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.1 0.4 0.0 0.0 1.0 2.0 0.0 1.0 0.0 0.0 1.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 1.3 1.1 0.5 0.6 0.6 0.9 0.5 0.5 1.0 0.5 0.0 1125.0 2573.3 0.0 0.0 0.0 71.4 3938.5 0.0 0.0 0.0 0.0 0.0 0.0 43564.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 113.5 0.0 0.0 0.1 0.0 0.0 304.5 0.0 0.5 691.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4534.8 0.0 0.0 0.7 0.0 128.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.8 0.0 0.0 0.0 134.7 0.0 0.0 9997.0 0.0 0.0 0.0 850.3 0.0 0.0 3.9 0.0 0.0 83.7 0.0 0.0 800.2 SCGB1C1 RYD5 ENSG00000188076 "Secretoglobin family 1C member 1" Q8TD33 11 193078-194575 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.3;pancreas: 1.4;retina: 3.4;salivary gland: 1.0" "Cell type enriched" "Detected in single" 5 "Macrophages: 2.7" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Region enhanced" "Detected in single" "pons: 1.3" "Group enriched" "Detected in some" 32 "basophil: 5.0;neutrophil: 1.3" "Lineage enriched" "Detected in single" 50 "granulocytes: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (5.09e-3)" 0.0 0.1 0.1 0.1 0.1 0.7 0.1 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 1.3 0.0 0.0 3.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.3 0.1 0.1 0.7 0.3 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCGB1C2 ENSG00000268320 "Secretoglobin family 1C member 2" P0DMR2 17 137569-139067 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 1.5;retina: 1.0" "Cell type enriched" "Detected in some" 4 "Muller glia cells: 5.0" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (4.65e-2)" 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.9 0.0 0.0 0.1 5.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCGB1D1 "LIPA, LPHA, MGC71958" ENSG00000168515 "Secretoglobin family 1D member 1" O95968 11 62190216-62193539 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "cervix: 1.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "endometrial cancer: 23.3;ovarian cancer: 16.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "SCLC-21H: 6.0" "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "unprognostic (6.95e-3)" "unprognostic (9.01e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 SCGB1D2 "LIPB, LPHB" ENSG00000124935 "Secretoglobin family 1D member 2" O95969 11 62242239-62244812 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 1227.2;cervix: 4002.8" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 3242.1;Glandular and luminal cells: 3417.9" "Group enriched" "Detected in many" 6 "breast cancer: 625.1;endometrial cancer: 226.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 10.4" HPA035318 Approved "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" "HPA035318: AB_10610421" "unprognostic (8.76e-2)" "unprognostic (2.14e-1)" "prognostic favorable (3.46e-6)" "unprognostic (2.39e-2)" "unprognostic (5.89e-2)" "unprognostic (4.72e-2)" "unprognostic (1.99e-1)" "unprognostic (6.43e-2)" "prognostic favorable (8.03e-6)" "unprognostic (1.55e-1)" "unprognostic (1.15e-2)" 12.9 4.9 4.1 0.0 4.0 0.0 1227.2 3.2 5.4 4002.8 13.8 0.3 0.1 89.0 355.8 10.1 110.3 0.1 3.1 3.5 4.4 10.1 0.2 0.1 0.1 4.7 5.7 1.1 4.5 0.5 5.2 0.2 4.2 8.6 0.2 1.8 69.2 2.9 7.2 342.4 0.4 0.0 3.5 0.0 0.3 0.2 4.3 0.4 0.6 6.0 0.0 0.2 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.4 0.1 0.0 1.8 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.0 3.2 5.4 3.5 4.4 4.7 5.7 4.2 3.5 4.3 4.6 2.1 0.0 0.0 0.0 1.6 27.4 4.8 0.0 0.0 0.5 647.8 251.6 10.9 0.0 0.0 7.3 0.0 0.0 5.3 0.0 23.5 0.3 0.0 3242.1 409.9 12.0 0.0 0.0 0.0 0.2 0.0 3.6 0.0 3417.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 15.0 823.6 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.7 0.0 46.1 0.0 0.9 0.0 0.2 8.6 0.0 0.0 0.0 7.0 0.1 20.0 0.0 0.0 1.1 SCGB1D4 IIS ENSG00000197745 "Secretoglobin family 1D member 4" Q6XE38 11 62296281-62299075 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "cervix: 52.3;endometrium 1: 15.6;epididymis: 43.7;fallopian tube: 53.7" "Cell type enriched" "Detected in some" 6 "Endometrial ciliated cells: 3089.4" "Cancer enriched" "Detected in some" 57 "endometrial cancer: 100.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in female reproductive system" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (2.26e-3)" "unprognostic (3.20e-1)" 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 52.3 0.0 0.0 0.0 15.6 43.7 0.0 53.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 3089.4 111.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 457.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.2 0.0 0.0 0.0 3.9 0.0 0.0 0.0 SCGB2A1 "LPHC, MGB2, MGC71973, UGB3" ENSG00000124939 "Secretoglobin family 2A member 1" O75556 11 62208673-62213943 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 2021.0;epididymis: 1372.0" "Group enriched" "Detected in many" 6 "Endometrial ciliated cells: 2506.4;Glandular and luminal cells: 2597.0" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 971.9" "Region enhanced" "Detected in some" "medulla oblongata: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 8.6" HPA034584 Enhanced Approved Vesicles "Secreted in other tissues" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Vesicles "HPA034584: AB_10602221" "unprognostic (7.73e-2)" "unprognostic (3.77e-1)" "prognostic favorable (1.22e-4)" "prognostic favorable (1.54e-8)" "unprognostic (2.98e-2)" "unprognostic (1.86e-2)" "unprognostic (3.39e-1)" "unprognostic (1.95e-1)" "unprognostic (2.69e-1)" "unprognostic (6.87e-3)" "prognostic favorable (6.36e-4)" "unprognostic (5.67e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" "unprognostic (3.35e-1)" 0.2 0.0 0.0 0.2 0.0 0.0 57.8 0.0 0.0 2021.0 0.1 12.7 1.3 118.8 1372.0 4.2 238.4 13.4 0.2 0.1 0.4 1.9 0.1 2.4 0.0 3.5 1.4 0.7 17.2 1.1 5.1 0.1 0.8 6.8 16.3 0.0 29.6 15.6 0.0 8.6 1.0 2.2 0.5 0.0 45.9 0.0 1.1 2.7 5.8 0.0 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.1 0.0 0.7 0.1 0.0 1.6 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.5 1.4 0.8 0.5 1.1 0.2 0.6 0.0 4.8 0.0 0.4 0.1 3.8 4.8 0.0 0.0 123.6 71.0 0.0 48.6 10.1 16.5 0.0 0.2 1.6 9.7 3.9 6.6 0.0 2506.4 397.7 7.6 37.1 0.0 0.0 5.3 0.0 3.8 26.5 2597.0 0.0 0.3 0.0 0.1 4.9 0.0 0.0 59.9 10.2 0.3 0.0 0.0 0.0 14.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 15.3 10.8 0.0 0.0 27.0 0.7 0.1 109.3 0.0 0.0 0.0 8.5 0.0 0.0 1.7 0.4 0.0 13.7 0.1 7.0 16.6 SCGB2A2 "MGB1, MGC71974, PSBP1, UGB2" ENSG00000110484 "Secretoglobin family 2A member 2" Q13296 11 62270158-62273160 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "breast: 2805.9;skin 1: 708.1" "Group enriched" "Detected in some" 11 "Breast glandular cells: 2119.6;Breast myoepithelial cells: 1028.8;Melanocytes: 1762.7" "Cancer enriched" "Detected in many" 23 "breast cancer: 823.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 124 "SK-BR-3: 18.0" CAB026270 Enhanced "Secreted in female reproductive system" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "CAB026270: AB_912980" "unprognostic (2.38e-1)" "unprognostic (7.28e-2)" "prognostic favorable (9.57e-8)" "unprognostic (4.17e-1)" "unprognostic (3.75e-1)" 34.4 0.2 0.0 0.0 0.0 0.0 2805.9 0.0 0.0 309.2 0.0 0.4 0.0 4.1 0.0 76.6 0.1 0.0 4.0 0.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 1.6 1.3 0.0 0.2 0.0 0.0 159.3 0.1 1.8 708.1 0.2 0.0 0.0 0.2 0.3 1.1 0.0 2.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 6.6 49.6 0.3 0.0 0.0 0.0 2119.6 1028.8 0.1 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 1.4 41.9 21.6 11.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 141.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 3.2 1762.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 10.9 0.0 9.2 0.0 0.0 0.0 SCGB2B2 "SCGB4A2, SCGBL" ENSG00000205209 "Secretoglobin family 2B member 2" Q4G0G5 19 34593329-34675699 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 8.6" "Cell type enhanced" "Detected in some" "Astrocytes: 63.6;Excitatory neurons: 32.8;Inhibitory neurons: 45.3;Late spermatids: 31.0;Oligodendrocyte precursor cells: 52.8;Oligodendrocytes: 104.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.2;U-266/70: 1.0" HPA046806 Uncertain "Secreted in other tissues" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA046806: AB_10962373" "unprognostic (9.99e-2)" "unprognostic (3.62e-1)" "unprognostic (9.51e-2)" "unprognostic (1.38e-5)" "unprognostic (4.80e-3)" "unprognostic (1.66e-1)" "unprognostic (2.03e-2)" "unprognostic (2.73e-2)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-3)" "unprognostic (3.67e-1)" "unprognostic (3.52e-2)" "unprognostic (2.90e-1)" "unprognostic (2.49e-1)" "unprognostic (3.40e-2)" "unprognostic (1.52e-1)" 0.3 0.4 0.7 0.0 1.0 0.1 0.9 0.4 0.9 0.1 0.1 0.2 0.1 0.3 2.6 0.9 0.3 0.2 0.3 0.6 0.7 0.3 0.5 0.5 0.3 1.0 1.0 0.2 8.6 0.3 0.3 0.2 0.9 0.3 0.2 0.6 0.3 0.5 0.7 2.9 0.2 0.1 0.5 0.4 0.3 2.0 1.0 0.1 0.5 1.1 0.3 0.4 0.1 0.9 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.2 0.4 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.4 0.2 0.4 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.4 0.3 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.0 1.0 0.4 0.4 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.4 0.9 0.6 0.7 1.0 1.0 0.9 0.5 1.0 0.9 0.0 0.0 0.0 63.6 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.1 0.0 0.2 0.0 0.0 32.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.3 0.0 0.0 0.0 0.0 31.0 0.0 0.0 3.6 17.8 0.0 0.0 0.0 52.8 104.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 SCGB3A1 "HIN-1, HIN1, LU105, PnSP-2, UGRP2" ENSG00000161055 "Secretoglobin family 3A member 1" Q96QR1 5 180590105-180591499 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 270.0;lung: 508.1;salivary gland: 746.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2883.9;Breast myoepithelial cells: 4199.8;Club cells: 13674.8;Respiratory ciliated cells: 3325.6;Urothelial cells: 3139.7" "Group enriched" "Detected in many" 7 "endometrial cancer: 114.2;lung cancer: 288.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 51.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "NB-4: 2.3;T-47d: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 10000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (7.70e-3)" "unprognostic (4.90e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-2)" "unprognostic (3.03e-1)" "unprognostic (1.36e-2)" "unprognostic (7.87e-3)" "unprognostic (2.00e-2)" "unprognostic (3.20e-1)" "unprognostic (4.88e-2)" "unprognostic (3.55e-2)" "unprognostic (7.19e-2)" "unprognostic (8.74e-3)" "unprognostic (5.43e-2)" "unprognostic (4.62e-1)" "unprognostic (4.50e-1)" "unprognostic (1.50e-2)" 1.8 1.5 1.1 0.2 1.2 0.5 122.4 0.7 1.2 270.0 11.7 0.5 0.6 1.5 1.2 74.8 29.9 2.9 0.7 1.1 5.9 1.5 7.0 508.1 0.4 1.4 1.6 2.0 18.2 0.0 12.6 0.1 1.0 37.9 0.0 0.0 746.5 2.4 0.3 4.9 1.0 0.0 1.2 9.4 50.7 3.0 3.0 0.8 3.1 0.0 0.8 14.5 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 20.3 2.4 17.2 13.3 1.8 3.3 4.5 10.1 0.0 5.9 5.0 0.0 0.0 51.8 0.2 4.3 2.6 1.1 1.2 0.7 1.2 1.1 5.9 1.4 1.6 1.0 1.2 3.0 1.5 36.4 173.1 1441.5 0.0 5.9 0.5 51.2 2883.9 0.6 0.0 1831.7 4199.8 0.4 1554.2 13674.8 0.0 0.0 0.0 30.4 0.1 0.0 20.5 0.1 1.6 0.1 40.5 0.0 10.7 0.2 1.6 0.3 15.2 3.6 1.7 35.3 1.0 68.9 1.1 0.4 0.0 0.0 0.1 1566.5 1.2 0.6 0.2 0.6 14.8 5.4 0.0 0.6 0.0 0.0 0.0 0.1 146.1 0.5 0.0 0.0 214.9 0.0 0.0 3325.6 0.0 0.0 1.6 305.2 0.3 4.4 140.8 0.4 0.0 20.2 0.1 0.2 3139.7 SCGB3A2 "LU103, PNSP1, UGRP1" ENSG00000164265 "Secretoglobin family 3A member 2" Q96PL1 5 147870682-147882191 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 124 "lung: 1271.2" "Group enriched" "Detected in some" 8 "Alveolar cells type 2: 4396.4;Club cells: 6565.6" "Cancer enriched" "Detected in some" 10 "lung cancer: 211.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 50 "basophil: 71.6" "Lineage enriched" "Detected in many" 50 "granulocytes: 71.6" "Cell line enhanced" "Detected in many" "A-431: 89.1;EFO-21: 52.3;NTERA-2: 61.0;PC-3: 302.9;SuSa: 120.6" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 800000 "Cluster 46: Basophils - DNA binding" "Cluster 19: Lung - Lung function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (3.85e-1)" "unprognostic (1.77e-1)" "unprognostic (2.99e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-2)" "unprognostic (3.17e-2)" "unprognostic (1.05e-2)" "unprognostic (1.90e-8)" "unprognostic (9.31e-3)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (9.11e-2)" 0.6 0.6 3.3 1.5 2.4 2.4 4.0 5.3 6.0 0.7 0.6 0.6 1.0 1.7 5.0 2.1 1.4 1.2 1.7 3.3 6.2 1.2 1.3 1271.2 2.8 3.4 1.2 2.1 0.6 0.7 1.1 2.0 3.1 1.1 1.8 10.2 6.2 1.4 2.1 5.0 1.4 0.9 0.3 4.2 4.1 1.9 2.0 1.3 7.2 0.8 2.2 0.7 0.1 2.6 89.1 1.3 1.1 2.0 1.1 0.6 2.3 1.4 0.3 0.2 0.2 0.5 1.1 0.4 52.3 0.3 0.8 0.8 2.5 1.3 0.5 0.3 1.6 3.4 10.5 0.3 0.0 0.7 3.3 1.4 0.8 0.7 0.0 2.0 0.2 0.3 2.4 1.1 0.2 1.7 0.9 0.8 61.0 0.0 302.9 0.2 0.9 0.3 1.2 0.7 4.3 1.1 12.3 1.1 0.2 120.6 1.3 0.6 1.7 1.2 35.5 1.6 1.3 1.7 1.4 0.4 0.4 1.5 4.1 71.6 1.0 0.2 0.4 0.7 0.1 0.2 0.2 0.2 0.6 0.4 0.0 0.2 0.4 1.4 0.9 0.3 0.2 0.1 3.3 2.4 5.3 6.0 3.3 6.2 3.4 1.2 3.1 0.3 2.0 2.6 0.0 618.6 4396.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 6565.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 14.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.2 106.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 16.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 623.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.2 SCMH1 Scml3 ENSG00000010803 "Scm polycomb group protein homolog 1" Q96GD3 1 41027200-41242154 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 125.4;Excitatory neurons: 161.3;Inhibitory neurons: 213.0;Microglial cells: 102.1;Oligodendrocyte precursor cells: 154.3;Oligodendrocytes: 77.9;Spermatocytes: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048898, HPA053292" Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA048898: , HPA053292: AB_2797246" "unprognostic (6.02e-2)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (3.82e-4)" "unprognostic (1.98e-2)" "unprognostic (8.77e-2)" "unprognostic (8.93e-3)" "unprognostic (2.77e-2)" "unprognostic (1.40e-1)" "unprognostic (7.38e-2)" "unprognostic (9.47e-2)" "unprognostic (1.63e-1)" "unprognostic (8.08e-2)" "prognostic favorable (5.80e-4)" 22.0 24.0 15.2 11.3 15.9 17.8 23.2 16.5 18.1 32.0 18.6 54.6 12.7 35.4 20.5 14.0 33.1 15.8 39.3 16.1 16.9 29.8 19.7 20.6 10.4 13.6 14.7 36.3 40.1 34.7 27.6 11.0 13.1 40.4 17.0 21.0 27.5 30.7 44.9 13.3 23.4 24.6 12.2 15.5 32.5 32.8 16.7 16.6 24.1 34.2 10.5 38.9 21.3 14.1 19.5 12.8 29.9 27.5 13.4 25.4 0.1 15.4 26.7 25.2 26.0 12.3 24.6 35.4 11.4 28.1 21.1 4.8 23.3 20.6 21.6 24.7 17.8 16.6 17.7 31.2 58.2 35.7 26.2 27.7 20.5 16.7 40.2 30.5 25.7 43.3 15.7 26.8 25.0 10.6 36.0 30.8 27.7 16.4 13.5 39.3 31.3 21.0 20.4 24.1 21.0 22.5 26.7 21.1 22.1 20.2 18.8 90.7 19.0 26.3 20.4 16.4 28.5 27.1 16.2 38.6 16.5 31.5 24.4 0.6 0.6 1.2 1.6 1.1 2.0 2.4 1.9 1.5 1.9 1.1 1.3 1.1 0.0 1.6 0.2 3.9 1.4 0.9 15.2 15.9 16.5 18.1 16.1 16.9 13.6 14.7 13.1 12.2 16.7 14.1 7.1 9.6 10.8 125.4 9.4 6.6 25.8 11.5 26.7 17.0 16.4 17.0 14.9 18.6 7.4 12.9 16.7 7.3 10.8 7.2 1.9 11.4 9.4 7.2 13.8 9.6 8.4 16.0 161.3 21.3 3.3 11.4 15.3 13.1 5.1 11.9 8.9 7.3 6.2 8.4 213.0 7.4 8.2 3.3 6.5 12.4 16.4 3.2 8.8 102.1 2.7 6.9 2.1 154.3 77.9 12.4 6.2 18.0 20.2 23.3 10.4 18.1 5.8 14.2 19.7 11.9 10.3 54.3 26.1 6.1 3.7 4.8 7.4 3.5 12.4 14.5 SCN1B ENSG00000105711 "Sodium voltage-gated channel beta subunit 1" Q07699 19 35030470-35040449 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 256.5;skeletal muscle: 572.0;tongue: 227.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 67.9;Excitatory neurons: 50.4;Hofbauer cells: 31.3;Inhibitory neurons: 48.3;Kupffer cells: 35.1;Macrophages: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 17.5;EFO-21: 12.7;TIME: 26.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 349.1" "Secreted in other tissues" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (8.18e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-2)" "unprognostic (6.40e-2)" "unprognostic (1.17e-2)" "unprognostic (2.69e-2)" "unprognostic (4.40e-2)" "unprognostic (1.20e-1)" "unprognostic (3.34e-2)" "unprognostic (4.72e-3)" "prognostic favorable (1.38e-4)" "unprognostic (2.25e-1)" "unprognostic (2.05e-2)" "unprognostic (9.68e-3)" "unprognostic (5.81e-2)" "unprognostic (4.12e-2)" "unprognostic (4.78e-2)" 20.2 13.6 48.2 3.3 53.0 2.3 16.3 95.8 256.5 15.5 7.7 9.7 1.9 9.4 2.2 8.6 21.7 4.8 95.4 45.0 97.2 8.3 8.5 11.1 3.0 120.4 67.0 7.8 12.3 18.2 17.4 5.3 115.7 8.7 2.7 10.7 15.4 3.6 572.0 6.3 8.0 4.5 52.2 19.8 8.4 2.8 153.5 1.3 11.1 227.8 0.8 13.4 10.5 113.6 0.4 17.5 0.2 1.0 5.2 7.8 0.1 7.1 6.1 3.4 0.9 0.7 0.2 0.2 12.7 7.1 3.0 0.3 1.1 0.7 1.6 0.2 0.8 0.2 2.5 4.5 6.9 0.1 0.1 2.5 0.1 0.4 0.2 6.8 11.6 0.2 0.4 0.1 2.2 1.7 0.2 0.2 0.8 1.6 5.1 0.9 1.8 0.2 0.5 0.1 8.1 4.3 0.9 0.1 1.4 0.6 1.6 0.4 26.1 6.7 6.6 0.3 4.6 0.3 0.5 1.0 4.0 0.8 4.8 0.7 0.2 0.1 0.3 0.1 0.6 0.1 0.1 0.1 0.6 0.2 0.1 0.1 0.7 0.2 0.1 0.1 0.3 0.7 48.2 53.0 95.8 256.5 45.0 97.2 120.4 67.0 115.7 52.2 153.5 113.6 12.8 0.0 3.3 11.8 1.1 1.8 0.8 1.6 0.0 67.9 1.6 7.7 20.3 0.0 0.6 0.0 2.1 0.4 2.9 0.0 9.8 0.3 0.3 2.0 2.0 9.7 0.0 0.4 50.4 2.6 0.6 9.9 2.0 1.8 2.5 0.1 20.7 1.2 31.3 8.4 48.3 1.6 0.0 35.1 3.7 0.0 7.5 29.5 3.6 15.9 3.0 13.3 0.0 6.0 18.5 0.7 0.1 2.2 2.7 1.1 0.1 2.5 1.0 22.8 0.0 25.3 3.6 0.2 0.7 0.1 1.1 1.0 2.0 0.1 0.8 0.3 SCPEP1 RISC ENSG00000121064 "Serine carboxypeptidase 1" Q9HB40 17 56978129-57006768 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 300.9" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 456.2;Club cells: 304.9;Respiratory ciliated cells: 397.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 319.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 389.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039102, HPA057200" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA039102: AB_10673605, HPA057200: AB_2683365" "unprognostic (5.83e-3)" "unprognostic (7.43e-3)" "unprognostic (4.47e-2)" "unprognostic (2.96e-1)" "unprognostic (9.26e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.00e-3)" "unprognostic (1.68e-1)" "unprognostic (1.70e-1)" "unprognostic (3.56e-3)" "unprognostic (1.40e-1)" "unprognostic (3.25e-1)" "unprognostic (7.28e-2)" "unprognostic (8.89e-2)" "unprognostic (8.33e-2)" "unprognostic (1.68e-1)" 64.1 121.5 25.7 32.6 26.4 75.8 91.0 27.3 42.9 69.8 34.5 46.9 31.4 37.5 73.1 54.8 48.5 71.2 60.1 27.2 30.9 88.6 32.0 95.1 48.7 30.1 29.5 53.6 17.0 300.9 28.7 20.8 30.6 61.6 33.7 8.1 90.0 102.9 15.8 46.3 40.3 60.9 28.7 44.8 54.2 14.3 28.4 14.6 135.1 32.5 60.6 71.1 51.1 33.6 48.3 20.9 49.4 41.4 389.3 85.6 26.0 23.3 119.6 41.9 77.8 13.7 33.3 63.3 126.4 55.9 65.8 44.0 22.0 105.4 46.8 82.0 36.1 19.8 28.2 8.7 89.1 39.1 190.1 103.7 45.0 52.0 43.0 37.5 72.3 24.3 5.1 257.9 59.1 20.3 19.9 100.4 20.4 15.2 39.3 24.2 53.8 41.4 9.3 143.7 13.8 33.8 56.3 45.6 33.3 57.1 19.1 104.1 34.1 118.3 29.9 68.8 26.5 250.5 187.2 35.9 88.1 28.5 34.4 2.1 228.5 319.0 11.8 137.1 8.0 56.0 8.2 8.3 105.7 55.1 11.3 12.3 34.8 23.7 141.0 18.0 10.2 118.7 25.7 26.4 27.3 42.9 27.2 30.9 30.1 29.5 30.6 28.7 28.4 33.6 48.8 44.8 61.8 25.1 52.7 23.7 208.6 456.2 37.5 12.7 52.4 110.7 32.5 10.0 304.9 95.6 16.7 9.9 20.5 2.0 19.6 22.2 1.0 51.5 24.5 27.1 24.4 21.2 37.2 6.8 19.4 115.4 4.6 13.6 8.2 4.3 62.8 15.7 160.5 10.1 24.9 5.0 126.1 135.0 33.7 3.4 64.3 110.2 24.9 20.6 142.2 18.9 25.7 21.1 20.7 4.8 1.6 68.1 39.0 74.1 62.4 29.7 397.8 17.0 52.6 28.1 63.2 4.4 12.3 38.1 19.9 11.1 18.8 67.1 8.0 122.6 SCRG1 SCRG-1 ENSG00000164106 "Stimulator of chondrogenesis 1" O75711 4 173384701-173406380 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7;choroid plexus: 15.2" "Cell type enhanced" "Detected in many" "Astrocytes: 46.4;Muller glia cells: 148.3;Oligodendrocyte precursor cells: 102.1" "Cancer enriched" "Detected in many" 6 "glioma: 35.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 5 "WM-115: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012882 Approved "Secreted in brain" NA NA 240000 "Cluster 17: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "HPA012882: AB_1856635" "unprognostic (1.09e-1)" "unprognostic (1.83e-2)" "unprognostic (2.60e-5)" "unprognostic (2.58e-1)" "unprognostic (3.22e-2)" "unprognostic (7.51e-2)" "unprognostic (3.58e-2)" "unprognostic (1.14e-3)" "unprognostic (2.08e-1)" "unprognostic (2.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (3.95e-10)" "unprognostic (4.86e-2)" "unprognostic (2.21e-1)" "unprognostic (4.34e-3)" "unprognostic (8.74e-4)" 1.3 0.8 19.0 0.6 20.5 0.7 0.5 20.6 30.7 1.6 15.2 4.4 0.5 1.8 0.9 0.4 2.5 1.5 2.9 19.4 20.3 0.2 0.1 0.4 0.2 22.8 19.9 0.8 0.3 0.0 1.0 0.2 22.5 2.3 0.5 2.3 1.1 3.2 0.5 0.5 0.9 4.7 21.6 0.5 2.8 10.8 19.4 0.0 0.3 0.0 0.1 2.0 0.8 24.7 0.1 0.0 0.6 0.2 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.5 0.2 0.1 3.5 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.1 17.1 1.8 0.5 0.3 0.2 0.4 0.1 0.2 0.1 0.2 0.2 0.3 0.2 0.3 1.2 0.5 0.5 0.3 0.1 0.1 19.0 20.5 20.6 30.7 19.4 20.3 22.8 19.9 22.5 21.6 19.4 24.7 1.3 0.0 3.0 46.4 1.0 3.6 1.1 0.0 0.0 14.5 2.4 3.9 1.3 0.0 0.7 0.0 37.5 0.2 3.3 0.3 0.0 0.3 18.3 0.7 1.7 2.1 1.2 0.0 19.0 0.0 0.4 17.3 1.1 0.4 8.9 0.9 4.2 0.3 0.6 16.8 20.9 0.5 0.0 3.3 2.6 32.3 26.1 3.8 23.2 2.8 1.9 148.3 2.1 102.1 26.4 0.2 0.1 20.7 1.0 1.9 0.4 0.3 0.8 28.3 13.1 2.4 20.3 3.1 2.4 0.1 2.6 0.7 3.1 0.5 0.3 1.0 SCT ENSG00000070031 Secretin P09683 11 626309-627181 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 44.2" "Cell type enhanced" "Detected in some" "dendritic cells: 92.8;Enteroendocrine cells: 267.8;Intestinal goblet cells: 46.4;Proximal enterocytes: 39.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 138 "plasmacytoid DC: 126.7" "Lineage enriched" "Detected in single" 138 "dendritic cells: 126.7" "Cell line enhanced" "Detected in single" "HSkMC: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050961 Enhanced "Secreted to blood" NA NA 571000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 56: Intestine - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA050961: AB_2681291" "unprognostic (5.28e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (3.70e-4)" "unprognostic (2.72e-1)" "unprognostic (7.91e-2)" "unprognostic (1.73e-1)" "unprognostic (2.43e-3)" "unprognostic (4.19e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-2)" "unprognostic (1.88e-1)" "unprognostic (1.33e-1)" "unprognostic (4.01e-2)" "unprognostic (8.37e-2)" "unprognostic (5.45e-1)" "unprognostic (6.09e-2)" "unprognostic (1.13e-1)" 0.1 0.2 0.7 0.1 1.8 0.6 0.0 1.9 1.9 0.3 0.0 0.9 44.2 0.1 0.3 0.3 0.2 0.0 1.8 0.7 0.3 0.4 0.4 2.2 1.3 1.3 0.7 0.4 0.2 0.0 2.0 0.7 1.5 0.6 0.1 0.2 0.2 0.0 10.3 0.1 8.6 0.0 0.1 3.3 0.7 3.0 1.4 0.4 0.5 1.3 0.7 0.3 0.1 4.1 0.1 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.9 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.9 0.0 126.7 0.0 0.4 0.7 1.8 1.9 1.9 0.7 0.3 1.3 0.7 1.5 0.1 1.4 4.1 0.1 0.0 0.0 0.7 4.1 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.4 1.5 0.0 0.0 0.0 0.1 92.8 1.6 1.9 0.0 1.7 0.3 0.3 0.1 267.8 0.0 0.0 0.0 0.0 1.9 1.1 0.4 0.0 3.5 0.4 0.0 0.2 0.0 0.1 46.4 0.0 0.0 1.2 1.1 1.5 3.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 13.6 0.0 0.0 0.2 39.2 0.2 0.0 0.0 0.0 1.6 0.2 0.8 10.2 0.0 0.1 0.0 0.1 0.1 3.2 0.2 SCUBE1 ENSG00000159307 "Signal peptide, CUB domain and EGF like domain containing 1" Q8IWY4 22 43197280-43343372 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 26.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 13.3;Granulosa cells: 37.2;Peritubular cells: 45.5;Theca cells: 14.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HMC-1: 49.8;THP-1: 20.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003190 Approved "Secreted to blood" NA NA 2170000 190000 "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA003190: AB_1079882" "unprognostic (5.29e-2)" "unprognostic (7.15e-6)" "unprognostic (6.03e-3)" "unprognostic (8.33e-2)" "unprognostic (3.65e-1)" "unprognostic (4.55e-2)" "unprognostic (1.34e-1)" "unprognostic (5.76e-2)" "unprognostic (1.10e-1)" "unprognostic (1.99e-1)" "unprognostic (3.74e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-2)" "unprognostic (1.02e-2)" "unprognostic (2.70e-1)" "unprognostic (2.30e-1)" "unprognostic (6.87e-3)" 1.8 6.1 0.8 0.8 1.1 0.1 1.2 0.1 1.4 0.9 4.1 3.8 5.9 1.1 0.1 3.6 1.2 0.8 0.2 0.6 3.8 3.5 5.1 6.8 0.0 1.7 10.2 26.4 0.1 9.1 3.8 2.6 7.0 1.9 2.0 0.4 3.6 0.5 9.6 0.6 7.7 0.5 0.3 5.7 7.0 7.1 1.2 0.1 3.1 1.9 0.0 3.3 0.7 0.4 0.0 0.0 2.2 7.8 0.0 0.0 4.9 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.1 0.1 0.3 0.1 0.7 0.0 0.0 0.1 0.7 0.0 0.1 0.7 0.2 0.2 49.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 0.0 0.1 0.1 0.2 0.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 1.2 0.0 0.1 0.0 0.3 0.1 20.4 0.0 0.3 0.2 0.6 0.0 2.1 4.3 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.1 1.4 0.6 3.8 1.7 10.2 7.0 0.3 1.2 0.4 0.2 9.6 1.7 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.9 0.1 1.4 0.0 0.6 0.0 0.0 0.2 0.2 0.0 1.9 0.1 3.0 1.3 1.2 1.3 0.0 0.0 0.4 0.0 13.3 2.6 0.5 3.4 1.3 37.2 0.4 1.9 0.8 0.0 0.3 0.2 0.0 0.0 0.4 4.6 7.8 0.2 0.0 0.0 0.1 4.1 0.0 0.0 0.3 0.1 0.0 45.5 0.4 0.0 0.0 0.4 0.7 0.2 0.0 0.4 1.2 3.8 2.0 0.0 0.1 0.4 2.8 14.3 0.0 0.1 SCUBE2 "Cegb1, Cegf1, FLJ16792" ENSG00000175356 "Signal peptide, CUB domain and EGF like domain containing 2" Q9NQ36 11 9019476-9138114 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 48.8" "Cell type enhanced" "Detected in many" "Adipocytes: 30.3;Basal prostatic cells: 51.4;Breast glandular cells: 45.0;Breast myoepithelial cells: 31.5;Prostatic glandular cells: 39.8" "Cancer enhanced" "Detected in all" "breast cancer: 54.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.0" "Lineage enriched" "Detected in single" 6 "monocytes: 1.0" "Cell line enhanced" "Detected in some" "HAP1: 5.7;SK-MEL-30: 8.1;T-47d: 28.4" "Group enriched" "Detected in some" 4 "olfactory bulb: 4.6;thalamus: 2.7" "Low region specificity" "Detected in all" "HPA006353, HPA029871" Uncertain "Secreted to blood" NA NA 1100000 "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "HPA006353: AB_1856642, HPA029871: AB_10602299" "prognostic favorable (2.41e-4)" "unprognostic (5.72e-3)" "unprognostic (2.91e-1)" "unprognostic (1.76e-2)" "unprognostic (2.73e-1)" "unprognostic (6.12e-4)" "unprognostic (3.11e-1)" "unprognostic (6.39e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (1.54e-2)" "unprognostic (3.04e-1)" "unprognostic (1.94e-2)" "unprognostic (9.12e-4)" "unprognostic (4.35e-1)" "unprognostic (5.94e-2)" "unprognostic (2.88e-1)" 14.8 2.0 3.5 3.7 3.5 0.0 32.2 13.7 3.1 17.6 0.2 11.1 3.6 13.4 48.8 4.5 18.2 7.9 4.3 4.0 4.9 1.3 0.9 4.6 3.9 3.0 3.6 0.9 22.0 19.5 9.6 22.5 3.7 33.3 4.5 1.9 2.3 8.7 9.0 12.3 16.3 13.0 5.4 5.0 21.4 2.2 4.7 2.4 5.2 6.2 7.6 28.6 6.9 5.1 0.0 0.1 1.5 0.9 0.5 0.6 0.2 1.6 0.8 0.9 0.6 0.3 0.0 0.0 0.6 3.9 0.1 0.0 5.7 0.0 1.4 0.1 0.3 0.0 0.0 0.0 0.6 0.0 0.1 1.3 0.0 0.4 0.0 0.3 0.6 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.9 0.0 0.0 0.1 0.0 0.2 0.4 3.1 0.7 1.0 1.1 0.1 8.1 1.3 28.4 0.0 0.0 0.6 0.4 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.5 3.5 13.7 3.1 4.0 4.9 3.0 3.6 3.7 5.4 4.7 5.1 30.3 16.0 9.2 1.6 0.0 7.4 51.4 0.3 1.2 0.4 45.0 31.5 0.6 0.0 5.6 1.8 0.0 0.2 0.1 1.0 0.0 0.1 3.4 2.2 8.8 3.3 1.2 0.0 3.1 1.8 0.2 9.4 0.0 6.4 0.0 0.3 1.1 0.1 0.8 13.5 14.9 5.2 6.1 0.3 1.5 2.5 0.3 0.7 19.6 5.6 0.1 0.0 0.0 13.6 4.6 0.1 4.3 0.7 0.0 39.8 0.6 0.0 1.5 0.3 0.0 5.2 1.5 0.6 0.7 0.1 1.8 0.4 0.3 6.6 9.6 15.6 SCUBE3 "CEGF3, FLJ34743" ENSG00000146197 "Signal peptide, CUB domain and EGF like domain containing 3" Q8IX30 6 35213956-35253079 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "thyroid gland: 28.9" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 10.8;Horizontal cells: 10.1;Rod photoreceptor cells: 7.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 26.0;ASC diff: 76.7;ASC TERT1: 102.2;HSkMC: 48.1;hTEC/SVTERT24-B: 30.1;U-138 MG: 29.1;WM-115: 25.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040606 Uncertain Approved "Plasma membrane" "Secreted to blood" NA NA 1890000 490000 "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA040606: AB_10795383" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (2.22e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (2.00e-2)" "unprognostic (7.41e-2)" "unprognostic (1.57e-1)" "unprognostic (2.64e-2)" "unprognostic (4.83e-8)" "unprognostic (1.54e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.06e-3)" 1.7 2.4 0.7 0.9 1.1 0.1 0.4 2.0 1.0 0.5 2.9 4.2 0.1 0.6 0.9 0.7 0.8 0.5 3.4 0.5 0.6 2.9 0.1 0.7 0.1 0.8 1.0 0.5 0.1 0.1 1.7 0.7 0.3 2.2 0.9 1.4 0.2 4.5 0.3 0.8 0.7 0.9 0.1 0.2 1.4 1.1 0.7 0.1 28.9 0.0 0.2 5.1 0.9 0.8 0.0 0.1 26.0 0.2 76.7 102.2 0.3 6.7 3.3 0.1 0.1 0.5 0.1 0.0 0.9 15.5 0.0 0.0 5.3 0.0 0.4 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.0 48.1 0.0 30.1 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.3 0.0 0.0 1.2 0.0 0.4 0.1 0.0 0.0 0.1 2.9 0.5 0.0 0.1 0.7 1.9 10.2 0.7 0.1 1.5 29.1 1.3 0.0 0.2 0.1 0.0 0.0 4.6 0.0 25.2 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.0 0.7 1.1 2.0 1.0 0.5 0.6 0.8 1.0 0.3 0.1 0.7 0.8 0.2 0.0 0.6 0.7 0.5 0.0 0.2 0.4 0.0 2.6 0.3 0.0 3.5 0.0 2.0 1.8 2.1 1.2 0.5 0.0 0.0 0.0 2.1 1.2 0.4 0.6 10.8 0.0 2.2 0.0 2.1 1.3 0.0 0.4 1.3 0.5 0.0 0.1 0.3 10.1 3.2 0.1 0.0 0.6 0.4 3.3 0.9 0.2 1.8 0.0 0.1 3.0 0.0 4.0 3.5 0.1 0.0 3.8 0.4 0.1 0.0 0.1 0.9 7.1 0.0 0.6 3.2 0.5 2.1 0.0 0.0 0.7 0.2 0.1 0.0 0.2 SDC1 "CD138, SDC, SYND1, syndecan" ENSG00000115884 "Syndecan 1" P18827 2 20200797-20225433 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 491.6;liver: 484.7;skin 1: 447.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 267.4;Hepatocytes: 603.1;Squamous epithelial cells: 246.6;Syncytiotrophoblasts: 250.8;Urothelial cells: 492.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 7 "midbrain: 17.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 482.2;hTCEpi: 436.6;U-251 MG: 470.0;U-266/70: 467.4;U-266/84: 1069.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB002424, HPA006185, HPA067477" Enhanced Approved "Focal adhesion sites" "Secreted to blood" NA NA 63100000 3100000 "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 22: Epithelial cell types - Mixed function" "Focal adhesion sites" "CAB002424: AB_442050, HPA006185: AB_1857705, HPA067477: " "prognostic unfavorable (2.22e-4)" "unprognostic (6.80e-3)" "unprognostic (6.80e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (4.02e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (3.66e-1)" "unprognostic (2.27e-3)" "unprognostic (1.79e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (4.27e-1)" "unprognostic (1.62e-2)" "unprognostic (1.52e-1)" 2.4 17.4 0.7 17.2 0.2 1.2 23.8 2.3 0.8 127.2 0.7 61.8 75.8 2.2 19.9 491.6 10.5 77.1 0.6 0.3 2.0 99.5 484.7 59.6 7.3 0.6 17.3 1.6 16.6 5.4 2.0 32.6 0.8 56.3 33.3 0.7 85.8 25.9 1.6 447.4 53.6 2.2 0.2 20.1 87.3 3.3 2.5 5.1 18.3 0.0 43.2 104.8 242.1 0.1 252.6 137.6 42.7 108.1 11.6 1.6 134.9 68.7 65.4 62.7 52.8 29.5 148.9 0.3 24.8 48.8 34.8 241.4 19.0 482.2 41.8 1.3 12.5 0.0 12.2 150.2 10.3 11.0 1.0 6.4 436.6 56.5 132.9 87.2 6.9 0.0 6.4 94.7 34.0 149.6 0.6 2.6 38.7 189.6 263.1 5.3 15.7 189.9 80.5 370.0 12.4 99.7 51.9 342.4 15.2 17.1 34.5 2.8 10.7 246.9 78.6 9.2 470.0 467.4 1069.8 1.0 74.5 0.6 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.2 2.3 0.8 0.3 2.0 0.6 17.3 0.8 0.2 2.5 0.1 0.4 93.0 99.0 0.0 33.0 113.9 189.1 162.8 81.4 0.6 29.9 26.7 0.9 267.4 161.8 42.3 0.0 3.8 0.7 147.2 31.3 61.3 0.1 16.6 5.0 3.5 10.8 13.5 0.3 21.8 46.3 5.0 55.0 22.9 6.3 7.5 7.5 603.1 2.3 21.9 0.2 73.1 50.8 10.6 11.9 0.3 0.6 2.5 21.4 0.0 0.6 0.3 0.0 1.0 0.0 111.4 78.0 1.2 165.1 78.0 106.5 88.5 43.4 0.4 0.0 0.1 15.0 1.0 14.0 246.6 229.0 250.8 4.0 0.1 85.1 492.8 SDF2 ENSG00000132581 "Stromal cell derived factor 2" Q99470 17 28648346-28662189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042799 Approved Vesicles "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA042799: AB_10794533" "unprognostic (3.91e-1)" "unprognostic (2.79e-1)" "unprognostic (2.03e-1)" "unprognostic (5.77e-3)" "unprognostic (3.90e-2)" "unprognostic (1.88e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.28e-3)" "unprognostic (3.20e-3)" "unprognostic (3.02e-1)" "unprognostic (1.04e-2)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.39e-3)" "unprognostic (2.21e-1)" "unprognostic (7.75e-3)" "unprognostic (6.61e-2)" 16.2 32.2 14.6 8.7 14.6 8.8 14.2 14.9 15.2 17.5 18.5 15.7 8.0 14.4 27.2 13.8 17.3 13.0 17.5 14.9 16.3 18.5 23.2 15.4 9.4 15.4 15.3 19.7 19.9 20.1 19.1 20.5 16.0 18.2 11.1 6.6 21.8 15.7 14.7 11.5 13.0 14.4 15.3 16.1 15.3 9.4 15.9 12.7 16.2 12.9 8.1 20.2 14.3 14.9 18.8 54.3 25.2 18.7 107.1 29.6 18.0 53.6 48.4 39.6 49.8 34.6 23.5 8.0 47.8 57.6 36.6 30.5 24.7 22.6 27.8 62.3 29.8 13.7 26.6 28.6 30.9 8.1 17.2 53.7 28.5 38.3 8.8 34.4 39.9 11.0 14.9 19.4 45.1 35.9 20.7 22.2 12.9 48.8 19.2 12.5 37.1 24.8 45.3 29.6 15.6 18.1 42.3 32.4 30.3 37.5 43.7 10.4 45.0 21.0 23.3 24.2 31.2 25.2 35.2 11.9 32.0 12.9 23.9 189.1 45.1 129.1 64.4 39.6 62.6 50.8 52.2 62.8 30.0 44.4 47.1 55.9 203.1 71.1 42.1 62.5 74.2 59.7 14.6 14.6 14.9 15.2 14.9 16.3 15.4 15.3 16.0 15.3 15.9 14.9 61.1 25.6 21.7 10.4 45.5 34.0 59.1 125.6 41.5 26.4 49.4 44.6 13.1 38.6 71.1 42.3 25.0 130.3 74.0 82.8 29.4 74.8 7.4 36.2 43.6 52.2 57.1 37.5 11.1 47.2 109.0 52.6 27.5 44.9 21.0 47.2 53.2 46.2 56.7 13.5 12.2 57.5 71.2 44.9 49.7 3.9 76.1 38.1 37.4 8.4 50.2 49.9 56.7 11.1 17.8 80.4 90.4 66.5 46.2 54.1 88.0 50.7 47.8 31.1 72.3 36.7 48.1 30.5 32.1 40.6 37.6 211.0 53.2 86.0 46.2 86.9 SDF2L1 "AP000553.C22.4, OTTHUMT00000075032" ENSG00000128228 "Stromal cell derived factor 2 like 1" Q9HCN8 22 21642302-21644299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 170.0" "Cell type enhanced" "Detected in all" "Plasma cells: 646.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 330.5" "Low region specificity" "Detected in all" HPA005638 Approved "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" "HPA005638: AB_1079888" "unprognostic (1.09e-1)" "unprognostic (2.76e-2)" "unprognostic (6.17e-2)" "prognostic favorable (4.98e-5)" "unprognostic (8.81e-3)" "unprognostic (2.29e-1)" "unprognostic (9.20e-2)" "unprognostic (2.30e-1)" "unprognostic (4.92e-2)" "unprognostic (6.88e-3)" "unprognostic (1.69e-2)" "unprognostic (1.48e-1)" "unprognostic (1.63e-2)" "unprognostic (3.44e-1)" "unprognostic (1.55e-1)" "unprognostic (1.70e-1)" "unprognostic (2.79e-2)" 28.5 40.4 14.0 31.1 15.1 25.8 23.6 15.9 18.8 25.0 22.2 36.3 24.9 33.0 21.7 30.9 29.8 5.7 41.0 14.3 20.7 43.8 170.0 35.9 16.9 19.0 16.2 16.0 94.6 10.0 77.3 11.7 16.0 32.7 9.8 1.4 48.0 11.5 17.3 19.5 35.7 7.1 16.2 68.2 40.9 35.0 17.0 9.6 89.9 1.7 11.9 33.2 21.5 17.2 77.3 64.6 15.9 53.4 9.2 11.9 99.6 66.5 16.6 31.4 34.5 66.8 44.9 70.1 59.4 16.0 50.7 62.2 29.8 45.9 8.5 51.4 179.7 53.3 70.1 147.5 52.8 53.7 89.6 8.9 19.6 29.4 30.6 10.9 31.1 37.1 330.5 175.8 13.4 146.4 52.8 76.4 17.6 82.8 110.3 48.6 36.4 58.9 22.2 57.0 33.8 52.2 33.6 56.8 36.5 12.5 54.5 62.9 35.9 16.6 92.1 55.7 41.4 160.6 70.7 52.0 32.7 62.1 49.8 114.0 98.9 44.6 173.3 106.8 130.2 131.8 109.2 156.8 72.6 124.9 86.5 102.7 29.8 101.0 102.2 218.5 126.9 106.3 14.0 15.1 15.9 18.8 14.3 20.7 19.0 16.2 16.0 16.2 17.0 17.2 52.3 25.6 28.5 2.6 164.7 114.2 125.1 89.0 16.5 5.6 80.2 57.8 35.8 62.9 50.3 49.7 35.5 94.7 98.0 194.2 25.4 121.2 52.3 59.3 47.7 58.0 186.1 51.1 1.5 177.5 342.9 64.6 53.0 65.0 111.3 19.0 61.4 286.2 224.1 5.0 2.2 344.8 48.8 68.7 205.4 31.4 32.3 85.9 211.7 6.5 69.4 62.0 145.2 4.0 4.6 175.5 169.6 16.6 646.4 203.8 129.8 96.5 40.9 13.0 39.5 26.2 53.0 276.5 218.9 23.9 112.5 168.1 85.1 37.5 188.1 129.4 SDF4 Cab45 ENSG00000078808 "Stromal cell derived factor 4" Q9BRK5 1 1216909-1232067 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 406.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011249, HPA011895, CAB015227" Supported Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA 2600000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "CAB015227: , HPA011249: AB_2668468, HPA011895: " "unprognostic (1.98e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (3.63e-1)" "unprognostic (2.38e-3)" "unprognostic (5.88e-2)" "unprognostic (7.95e-3)" "unprognostic (3.73e-3)" "unprognostic (1.06e-1)" "unprognostic (2.01e-1)" "unprognostic (8.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.04e-2)" 86.5 91.8 44.2 78.8 47.8 56.2 80.2 47.2 65.3 84.4 72.5 95.9 117.1 91.8 43.9 66.3 74.6 66.2 134.6 45.5 44.8 89.6 160.7 82.0 53.4 53.2 46.1 85.4 104.6 61.5 78.5 73.3 47.0 76.9 60.4 25.7 83.5 52.2 78.9 72.9 116.8 58.2 43.5 78.0 93.6 71.7 50.5 34.6 81.8 47.7 39.6 82.2 71.6 45.9 139.7 123.7 67.1 214.0 320.0 160.4 80.5 266.1 241.4 191.2 159.4 147.0 236.2 87.8 201.8 258.0 137.4 140.4 77.5 117.1 58.2 147.9 133.0 153.6 185.7 207.8 147.4 156.7 199.2 199.0 59.5 144.6 81.2 186.5 155.9 57.3 129.2 225.0 95.7 101.1 77.8 158.9 61.7 158.0 167.1 85.8 86.5 234.4 127.2 66.4 243.3 86.7 177.2 208.2 182.8 59.0 108.0 176.7 198.8 196.2 107.0 149.5 154.2 138.9 141.2 144.6 222.9 289.7 87.1 14.4 21.5 30.8 19.3 14.6 14.6 13.5 27.6 28.4 21.9 16.8 16.0 14.1 16.9 26.8 23.2 14.0 25.1 11.8 44.2 47.8 47.2 65.3 45.5 44.8 53.2 46.1 47.0 43.5 50.5 45.9 92.9 22.4 19.2 18.6 62.5 119.8 74.0 24.6 46.7 34.5 51.2 47.6 35.7 68.6 28.9 49.7 18.8 124.1 68.4 240.0 11.7 79.0 39.1 49.0 76.2 77.8 65.5 32.8 21.1 71.4 284.4 117.1 81.1 60.8 36.2 61.4 76.4 117.1 122.4 38.7 23.5 174.9 30.5 73.7 154.8 36.8 95.4 62.8 167.2 13.1 50.8 64.9 111.2 13.6 17.5 73.0 213.5 76.0 202.5 101.5 406.2 57.7 18.4 40.0 59.2 69.8 75.1 101.7 63.5 53.2 114.2 168.0 73.4 88.7 181.0 71.1 SDHAF4 "C6orf57, Sdh8" ENSG00000154079 "Succinate dehydrogenase complex assembly factor 4" Q5VUM1 6 70566917-70589569 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031824 Supported Approved Nucleoplasm,Mitochondria "Intracellular and membrane" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" Mitochondria Nucleoplasm "HPA031824: AB_10602113" "unprognostic (8.72e-2)" "unprognostic (1.64e-1)" "unprognostic (4.95e-2)" "unprognostic (9.96e-2)" "unprognostic (4.58e-1)" "unprognostic (2.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (1.42e-3)" "unprognostic (3.18e-2)" "unprognostic (3.17e-1)" "prognostic favorable (1.95e-5)" "unprognostic (2.45e-2)" "unprognostic (9.37e-2)" "unprognostic (3.05e-1)" "unprognostic (9.94e-2)" 11.2 12.3 7.1 4.2 7.5 4.3 10.5 6.8 10.5 6.6 7.3 6.8 5.0 5.8 9.3 7.5 10.3 4.2 14.5 7.6 9.4 12.5 8.5 5.4 6.0 6.9 6.3 6.4 6.6 14.4 12.7 6.8 7.3 7.6 6.7 10.0 8.7 5.4 23.6 8.6 5.4 4.2 5.8 5.6 7.0 5.3 7.8 6.4 7.3 10.6 5.2 6.8 6.7 7.6 13.3 4.2 18.8 11.6 9.0 13.6 3.5 7.1 5.1 3.4 5.0 3.8 11.3 9.1 12.7 3.8 8.0 2.3 6.2 5.9 5.2 18.3 4.3 6.6 1.8 3.9 15.3 6.3 5.1 9.6 19.3 2.6 14.8 11.6 8.0 14.8 4.2 13.9 11.0 9.0 5.9 15.7 8.8 6.5 4.5 6.4 12.6 10.8 14.9 4.4 16.8 12.1 4.3 2.1 9.6 8.0 9.6 16.5 6.3 3.5 2.7 2.8 7.7 6.2 4.5 3.1 3.9 15.1 8.5 4.0 4.6 4.4 3.4 4.3 3.3 3.7 3.7 4.1 5.1 4.7 3.9 3.8 3.3 4.7 4.6 6.2 4.2 3.0 7.1 7.5 6.8 10.5 7.6 9.4 6.9 6.3 7.3 5.8 7.8 7.6 5.4 12.8 13.9 4.9 3.3 0.0 7.9 0.0 3.4 7.4 6.5 7.5 21.3 10.0 5.6 7.3 8.4 10.5 5.0 2.9 23.5 9.1 5.5 20.2 8.2 5.0 3.6 2.5 7.7 11.6 8.5 6.6 2.6 6.0 5.1 6.1 4.2 11.8 10.0 18.5 7.5 5.8 0.0 5.3 0.0 2.5 12.5 6.2 0.0 2.8 10.1 10.1 3.1 12.1 7.7 13.2 5.3 6.8 2.2 9.5 6.2 16.8 13.8 6.4 13.1 5.1 4.9 10.0 6.1 5.7 0.0 5.1 3.9 6.1 5.3 8.0 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 491.5;tongue: 580.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.5;Proximal tubular cells: 449.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" NA NA 7900 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 85.8 95.7 68.0 59.0 72.2 94.6 68.7 80.6 84.3 56.8 81.1 134.3 163.0 56.0 71.0 77.4 59.8 48.0 302.8 69.9 76.9 228.0 336.1 56.1 75.3 74.8 71.4 44.4 80.3 144.3 42.8 57.6 73.8 55.7 132.4 62.9 74.0 60.5 491.5 55.6 121.9 70.4 73.9 60.5 92.8 64.4 74.9 62.7 64.3 580.6 84.2 71.3 52.0 78.9 157.3 152.7 72.2 107.8 141.6 135.2 95.9 122.4 145.2 254.3 227.7 216.8 183.1 206.8 159.3 156.4 176.1 180.1 290.7 226.8 284.8 128.7 280.6 183.4 149.2 168.2 172.8 276.0 135.6 140.4 154.9 224.5 370.1 138.7 183.6 176.5 165.2 236.9 179.6 129.5 182.4 175.1 70.4 224.6 302.6 146.1 142.5 265.4 252.4 88.7 157.5 86.0 172.3 216.3 392.3 76.4 131.1 169.1 94.9 115.8 131.0 206.4 176.0 98.9 133.3 198.6 170.4 438.5 128.3 68.7 149.8 149.5 71.4 206.5 70.7 89.9 81.0 77.5 186.8 81.1 73.5 74.8 174.3 85.3 185.7 89.3 113.8 116.1 68.0 72.2 80.6 84.3 69.9 76.9 74.8 71.4 73.8 73.9 74.9 78.9 48.2 64.1 47.4 20.9 57.4 52.1 93.3 199.8 40.5 31.5 45.2 49.4 405.5 101.5 97.0 47.8 14.6 107.1 48.3 176.1 354.1 134.3 220.3 48.7 38.2 54.7 48.6 77.3 27.7 149.2 142.2 62.0 46.9 45.5 66.6 39.9 46.8 226.0 177.4 37.0 32.1 103.1 116.0 88.7 67.9 30.5 57.8 78.4 64.0 29.0 123.1 78.3 48.4 15.6 24.6 111.5 218.3 67.7 62.2 74.4 300.5 449.0 79.8 53.8 39.5 57.1 191.6 148.9 71.5 72.9 54.6 121.8 46.8 69.3 162.0 110.9 SDHD "cybS, PGL, PGL1" ENSG00000204370 "Succinate dehydrogenase complex subunit D" O14521 11 112086824-112120016 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 530.2;Proximal tubular cells: 449.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045727 Approved "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "HPA045727: AB_10963114" "unprognostic (9.13e-2)" "unprognostic (3.51e-2)" "unprognostic (4.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.93e-1)" "unprognostic (4.98e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-3)" "unprognostic (7.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.99e-10)" "unprognostic (5.14e-2)" "unprognostic (1.58e-2)" "unprognostic (1.56e-2)" "unprognostic (7.51e-2)" 117.5 95.7 60.0 84.5 63.1 72.9 102.6 68.6 76.3 92.5 65.1 185.2 208.1 88.2 96.7 126.7 92.6 85.6 254.7 60.1 65.4 319.9 391.8 79.3 131.7 63.4 62.5 91.6 77.8 152.4 37.0 95.0 63.2 87.9 190.8 37.4 112.6 100.9 354.7 64.3 175.6 98.1 64.7 85.1 101.1 34.1 63.7 102.5 136.8 449.6 124.8 117.9 76.4 68.2 84.0 67.3 58.1 89.4 212.0 170.7 97.3 97.5 147.6 106.8 132.2 244.8 222.1 155.5 288.4 131.0 156.1 203.5 175.4 139.8 129.8 129.9 92.4 142.8 51.9 140.1 165.6 222.4 107.5 189.6 160.2 110.5 189.1 124.6 153.0 109.6 156.0 208.7 135.0 95.2 143.9 215.0 77.4 333.8 211.6 126.2 145.8 294.4 221.6 175.2 83.5 55.8 135.3 194.8 107.0 81.8 198.9 164.2 108.0 103.8 132.3 114.7 95.0 59.1 73.2 270.7 58.8 297.0 100.5 233.7 293.3 208.8 158.4 390.1 173.1 235.2 170.8 168.8 308.7 198.1 204.3 191.8 257.5 207.9 322.9 151.7 189.9 348.9 60.0 63.1 68.6 76.3 60.1 65.4 63.4 62.5 63.2 64.7 63.7 68.2 104.3 80.1 51.1 12.4 78.0 81.6 102.2 262.2 83.6 12.2 61.0 78.4 216.5 120.1 108.1 90.1 8.4 154.3 55.2 203.8 530.2 82.9 9.9 41.6 67.6 76.4 50.4 70.2 9.6 58.9 124.1 104.6 75.4 41.2 65.9 32.3 76.8 169.7 162.9 11.8 11.2 129.1 154.6 97.1 74.4 37.0 104.1 94.2 76.5 9.4 118.6 52.9 75.2 8.0 9.7 54.1 134.2 99.6 80.9 61.6 253.1 449.9 60.5 18.9 92.1 78.3 110.7 70.4 55.8 127.1 74.4 179.0 71.4 86.2 176.0 98.6 SEC13 "D3S1231E, npp-20, SEC13L1, SEC13R" ENSG00000157020 "SEC13 homolog, nuclear pore and COPII coat complex component" P55735 3 10293131-10321112 "Metabolic proteins, Predicted intracellular proteins, Transporters" "ER-Golgi transport, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035292, HPA057943" Approved Supported Nucleoplasm,Vesicles NA NA 35000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA035292: AB_10959451, HPA057943: AB_2683560" "unprognostic (3.33e-3)" "unprognostic (6.16e-2)" "unprognostic (2.28e-2)" "unprognostic (4.95e-2)" "unprognostic (4.22e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (2.43e-1)" "unprognostic (2.67e-1)" "unprognostic (1.69e-1)" "unprognostic (4.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.40e-1)" "unprognostic (4.60e-1)" "unprognostic (2.43e-1)" "unprognostic (2.03e-1)" "unprognostic (8.33e-2)" 62.1 71.5 51.0 61.8 55.6 58.4 58.9 55.9 57.6 83.7 59.2 68.8 114.7 66.4 59.4 72.6 57.4 47.5 71.1 52.2 57.2 67.4 92.1 64.3 54.6 54.6 54.6 52.6 85.2 64.6 109.2 68.5 55.2 53.8 65.7 21.2 96.2 64.9 111.5 62.7 96.6 76.6 54.3 59.4 67.3 39.4 54.2 70.3 57.6 87.3 65.4 69.9 59.2 58.2 122.6 182.1 142.9 55.2 228.0 251.6 474.4 243.8 296.1 279.3 319.8 150.3 97.6 110.7 109.6 390.1 156.8 49.0 186.4 218.3 142.4 97.8 194.5 136.2 137.3 363.7 311.8 156.7 115.5 224.7 173.1 292.6 181.5 205.6 337.0 146.2 148.4 159.8 219.5 250.2 153.8 169.9 160.9 158.0 218.7 148.1 102.4 198.2 172.4 90.2 80.3 99.4 107.3 98.7 101.3 119.3 127.5 150.8 253.6 114.2 130.2 172.6 213.3 131.7 198.4 258.6 215.5 217.5 193.0 127.3 163.2 106.6 84.4 144.9 94.6 96.5 83.6 82.1 222.5 82.6 68.0 71.2 105.8 93.9 116.4 198.3 106.1 176.5 51.0 55.6 55.9 57.6 52.2 57.2 54.6 54.6 55.2 54.3 54.2 58.2 23.9 48.1 61.9 14.0 45.8 39.4 50.4 73.6 31.3 16.2 29.5 26.4 40.2 30.0 68.3 27.6 10.4 119.9 36.5 60.1 66.5 79.3 25.6 31.8 44.0 51.0 41.4 33.0 17.3 109.2 166.6 74.1 73.9 47.1 43.1 35.5 33.9 57.3 104.9 11.8 13.7 108.2 50.8 33.0 46.7 10.2 53.4 45.0 26.6 12.2 64.2 37.4 35.0 11.6 12.6 81.8 56.1 52.6 203.2 52.4 187.5 112.0 64.5 21.1 13.1 37.7 63.6 54.9 38.9 43.7 40.2 168.6 36.5 35.8 74.2 62.3 SEC14L3 TAP2 ENSG00000100012 "SEC14 like lipid binding 3" Q9UDX4 22 30447959-30472017 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.8;liver: 2.9;retina: 9.0" "Group enriched" "Detected in some" 8 "Muller glia cells: 27.6;Respiratory ciliated cells: 22.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA059450 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: Muller glia cells - Visual perception" "HPA059450: AB_2684024" "unprognostic (2.42e-1)" "unprognostic (2.56e-1)" "unprognostic (1.42e-1)" "unprognostic (5.35e-2)" "unprognostic (2.00e-4)" "unprognostic (3.62e-3)" "unprognostic (6.68e-2)" "unprognostic (3.19e-1)" "unprognostic (2.41e-10)" "unprognostic (1.27e-1)" "unprognostic (2.09e-1)" "unprognostic (4.10e-1)" 0.0 0.1 0.2 0.1 0.1 3.8 0.0 0.3 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 2.9 1.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 1.7 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.3 0.2 0.0 0.2 0.0 0.2 0.0 0.1 0.4 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.7 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SEC16A "KIAA0310, p250, Sec16L" ENSG00000148396 "SEC16 homolog A, endoplasmic reticulum export factor" O15027 9 136440096-136483759 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005684 Supported Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 48000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "Endoplasmic reticulum" "HPA005684: AB_1079189" "unprognostic (1.24e-3)" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "prognostic favorable (1.30e-6)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.84e-2)" "unprognostic (3.48e-1)" "unprognostic (5.30e-2)" "unprognostic (1.38e-3)" "unprognostic (4.75e-1)" "prognostic favorable (4.47e-4)" "unprognostic (5.57e-3)" "unprognostic (2.64e-1)" "unprognostic (2.47e-2)" "unprognostic (1.41e-1)" 16.8 18.2 6.4 16.6 6.7 35.3 17.1 8.0 9.4 16.6 19.3 17.3 14.9 17.9 9.0 17.9 16.4 12.4 14.5 7.0 5.2 14.3 37.9 19.4 16.9 4.4 4.9 16.2 29.2 14.0 24.3 10.8 3.5 18.7 10.5 9.2 25.8 13.1 23.5 19.7 19.1 10.7 2.4 20.7 27.2 17.6 5.2 17.4 15.3 11.9 12.3 15.9 14.5 5.0 26.5 57.7 28.5 47.2 29.6 30.3 33.6 32.1 27.9 23.4 17.8 41.9 22.1 26.4 22.1 39.2 28.8 71.3 31.8 46.2 12.7 56.2 20.7 26.9 55.1 33.7 28.6 46.2 45.8 32.8 32.5 32.7 38.1 18.9 32.2 34.5 34.1 35.6 25.0 114.3 31.2 24.9 25.1 79.0 40.4 44.3 35.2 45.0 23.8 35.0 40.0 26.6 41.6 62.2 19.8 13.8 63.6 35.9 47.0 37.6 28.1 30.8 25.2 16.9 27.7 33.4 29.2 20.6 38.3 1.7 2.8 1.2 2.5 3.1 2.7 2.3 2.6 3.0 1.6 1.4 1.6 2.8 2.0 1.5 3.4 2.6 1.9 2.4 6.4 6.7 8.0 9.4 7.0 5.2 4.4 4.9 3.5 2.4 5.2 5.0 20.0 25.6 41.7 16.6 16.4 24.9 15.3 18.4 10.8 20.2 38.7 30.6 11.5 12.8 23.6 12.9 25.0 8.1 17.5 30.1 7.9 14.2 5.1 26.9 19.5 18.2 40.7 12.0 27.4 16.4 11.8 16.0 46.9 38.2 23.5 25.4 17.9 62.2 16.5 33.7 19.2 65.5 20.3 23.4 19.5 6.0 13.1 22.3 14.2 17.8 19.5 13.0 11.3 9.5 14.7 22.8 14.7 16.6 25.1 26.3 22.3 10.1 34.7 17.1 13.1 20.5 16.6 24.4 16.1 17.2 26.9 15.1 17.8 15.8 22.8 22.1 SEC22A SEC22L2 ENSG00000121542 "SEC22 homolog A, vesicle trafficking protein" Q96IW7 3 123201927-123274136 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 67.5;Inhibitory neurons: 67.5;Oligodendrocytes: 75.0;Spermatocytes: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (2.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.96e-1)" "unprognostic (8.25e-3)" "unprognostic (2.16e-1)" "unprognostic (9.04e-2)" "unprognostic (1.13e-2)" "unprognostic (4.91e-2)" "unprognostic (6.59e-2)" "unprognostic (2.16e-1)" "unprognostic (2.05e-1)" "unprognostic (2.66e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.46e-1)" "unprognostic (1.61e-1)" "unprognostic (3.03e-2)" "unprognostic (5.25e-1)" 10.4 11.2 6.6 8.1 6.9 4.6 10.9 8.6 6.9 10.5 6.8 8.9 6.8 9.6 8.8 12.3 9.6 9.0 8.0 7.5 6.8 10.5 12.9 9.2 10.3 6.2 6.8 10.6 10.1 9.5 11.3 10.1 7.2 8.9 9.5 9.9 9.6 7.3 6.1 13.7 8.5 11.6 6.1 9.8 8.4 21.5 7.0 10.2 9.9 5.5 13.1 8.9 10.0 8.0 40.4 12.5 20.2 15.6 27.1 25.4 20.2 35.3 22.2 20.4 28.8 10.3 22.0 20.9 25.8 19.9 23.8 30.5 16.0 20.8 34.0 9.1 13.6 14.1 11.7 9.0 24.7 18.3 11.6 18.2 27.2 19.4 18.7 20.5 27.6 18.3 9.4 17.4 20.6 17.6 17.0 13.5 7.1 29.2 25.0 12.9 21.5 21.2 18.6 11.0 14.6 11.3 20.8 14.5 21.0 14.6 30.2 22.5 12.6 17.8 19.5 29.4 21.5 11.4 11.4 34.6 26.5 20.5 27.3 19.3 19.9 16.7 24.1 19.3 29.8 18.7 24.7 26.4 19.9 15.7 26.3 22.0 2.9 28.9 19.5 19.2 27.6 16.9 6.6 6.9 8.6 6.9 7.5 6.8 6.2 6.8 7.2 6.1 7.0 8.0 10.5 3.2 12.1 39.8 13.9 8.4 17.9 29.7 10.8 7.5 7.9 7.4 5.6 17.2 20.4 7.3 4.2 27.5 7.3 6.1 9.8 17.8 30.5 4.7 9.0 9.8 7.8 8.6 67.5 10.4 19.5 12.5 12.2 6.4 7.0 11.6 12.1 9.0 13.6 1.7 67.5 9.4 10.2 5.0 8.0 16.5 12.2 7.8 5.4 56.2 11.7 6.7 9.2 59.3 75.0 11.3 4.6 6.8 18.4 9.9 5.7 9.5 11.1 7.6 19.7 8.8 12.3 75.6 17.0 12.1 9.5 44.1 12.9 11.2 6.8 10.9 SEC22C "MGC13261, MGC5373, SEC22L3" ENSG00000093183 "SEC22 homolog C, vesicle trafficking protein" Q9BRL7 3 42547969-42601080 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031242 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" Nucleoplasm "HPA031242: " "unprognostic (1.68e-1)" "unprognostic (4.86e-2)" "unprognostic (1.01e-1)" "unprognostic (2.67e-1)" "unprognostic (9.37e-3)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.04e-5)" "unprognostic (1.15e-1)" "unprognostic (3.27e-1)" "unprognostic (1.44e-1)" "unprognostic (3.58e-2)" "unprognostic (2.57e-1)" "prognostic favorable (1.35e-7)" "unprognostic (2.59e-1)" "unprognostic (3.30e-1)" "unprognostic (7.51e-2)" "unprognostic (1.41e-3)" 35.7 23.4 37.3 14.1 40.8 36.5 33.2 39.1 46.8 28.2 33.8 31.1 31.9 29.8 27.4 17.2 27.2 18.9 24.3 34.1 38.0 26.2 16.4 33.1 19.0 41.4 40.3 29.3 29.6 26.4 26.6 19.3 42.0 37.3 15.6 25.6 23.3 25.9 22.2 19.4 32.6 26.3 37.5 20.4 28.3 27.5 39.2 18.2 24.2 26.1 16.4 25.7 23.1 48.1 24.0 22.2 35.9 30.5 72.4 68.1 7.6 43.8 46.7 46.1 47.9 15.5 37.9 24.5 17.6 50.1 28.2 12.6 24.1 39.8 40.7 32.8 28.5 41.7 40.0 21.0 55.4 19.2 39.5 38.3 53.1 51.4 62.5 46.5 51.1 38.7 37.0 46.5 45.8 16.6 27.1 22.3 19.8 16.0 31.9 11.7 21.4 22.9 40.6 21.1 18.5 27.8 30.9 28.0 34.5 26.5 48.4 20.9 42.9 35.1 27.8 63.8 43.1 36.8 55.6 23.5 41.7 26.6 34.0 11.7 11.5 22.0 13.2 9.0 19.6 11.5 17.6 16.3 10.8 9.4 14.9 13.2 7.1 10.2 9.3 11.3 16.3 10.1 37.3 40.8 39.1 46.8 34.1 38.0 41.4 40.3 42.0 37.5 39.2 48.1 31.4 25.6 27.6 27.1 23.2 15.0 18.3 25.3 25.0 16.6 31.6 29.6 18.8 24.3 17.2 11.0 29.2 20.5 28.1 1.9 41.1 29.7 61.2 17.5 19.5 30.5 9.0 48.2 18.9 32.9 20.3 31.8 21.9 12.7 49.4 25.1 32.2 14.5 31.3 26.9 18.4 4.9 32.6 19.0 14.4 15.0 32.6 17.6 40.9 21.5 35.5 39.2 24.7 12.5 44.1 28.8 1.0 42.9 23.0 24.0 36.9 29.6 19.4 39.9 39.5 26.6 31.1 96.9 49.8 11.3 10.2 10.5 34.6 20.3 6.6 9.4 SEC23A ENSG00000100934 "Sec23 homolog A, COPII coat complex component" Q15436 14 39031919-39109646 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 347.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043806, HPA069974" Uncertain Approved Nucleoplasm,Vesicles NA NA 83000 "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA043806: , HPA069974: AB_2686223" "unprognostic (2.40e-1)" "prognostic unfavorable (5.75e-4)" "prognostic favorable (3.56e-4)" "unprognostic (3.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (1.15e-2)" "unprognostic (5.85e-2)" "unprognostic (1.71e-1)" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (1.69e-4)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.16e-1)" "unprognostic (2.73e-1)" "unprognostic (1.41e-3)" 45.9 32.0 11.4 31.8 14.2 13.1 20.9 18.3 16.8 36.2 31.4 40.0 57.7 42.7 19.9 34.1 21.5 32.1 46.9 13.3 18.9 23.1 80.8 20.2 21.0 13.8 14.0 33.9 12.0 8.1 10.5 27.1 15.3 34.0 34.2 38.5 10.5 52.6 54.2 12.8 52.6 90.5 7.6 20.5 16.8 23.5 12.7 18.9 17.9 58.5 22.0 40.7 17.9 15.4 52.1 90.8 76.9 74.7 161.3 173.0 25.9 195.1 176.4 135.2 166.8 93.2 44.2 12.6 46.9 279.6 54.9 41.2 99.6 86.3 208.6 39.6 36.9 21.8 67.7 347.3 122.4 35.9 31.3 134.0 48.8 91.6 73.7 114.6 130.8 26.9 15.6 30.1 125.8 47.5 32.9 16.9 18.4 81.7 91.3 44.0 111.8 19.1 84.7 75.6 8.5 20.5 132.8 43.0 51.8 68.6 51.5 12.4 138.4 75.0 57.8 110.8 52.0 27.0 36.6 56.0 50.3 31.4 70.2 70.5 34.3 38.6 26.6 29.3 38.4 23.6 33.1 34.9 31.1 21.1 34.9 28.0 29.5 42.1 27.3 26.7 38.1 31.4 11.4 14.2 18.3 16.8 13.3 18.9 13.8 14.0 15.3 7.6 12.7 15.4 35.4 16.0 26.9 34.9 30.5 25.9 33.5 15.5 15.4 39.7 11.8 10.3 54.6 15.7 18.8 31.3 68.8 16.0 36.0 87.0 7.9 9.8 13.4 11.3 42.8 41.1 24.5 6.1 48.3 5.6 43.7 55.0 26.5 18.8 27.9 56.9 118.9 133.6 25.6 30.3 51.1 31.6 12.2 36.4 32.3 18.6 74.9 24.3 24.9 48.7 25.6 19.4 32.0 34.2 44.3 17.8 34.1 71.5 38.5 37.5 88.6 32.8 10.1 58.7 39.5 27.6 51.4 18.0 15.5 15.7 24.0 24.8 32.3 31.0 30.2 56.5 SEC24B ENSG00000138802 "SEC24 homolog B, COPII coat complex component" O95487 4 109433772-109540896 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 88.1;Oligodendrocytes: 91.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038181 Approved Approved Nucleoplasm,Vesicles NA NA 14000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Vesicles" "HPA038181: AB_10672472" "unprognostic (1.19e-1)" "unprognostic (4.31e-3)" "unprognostic (8.58e-3)" "unprognostic (9.95e-2)" "unprognostic (1.22e-1)" "unprognostic (1.46e-1)" "unprognostic (6.67e-2)" "unprognostic (3.18e-2)" "unprognostic (1.06e-1)" "unprognostic (1.85e-3)" "unprognostic (2.51e-3)" "unprognostic (7.47e-2)" "prognostic favorable (2.33e-6)" "unprognostic (2.67e-1)" "unprognostic (2.40e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" 19.3 13.7 7.2 13.2 7.5 28.0 17.4 14.7 9.9 16.3 15.0 15.7 14.1 16.9 12.9 17.2 15.0 13.8 15.6 6.8 7.6 16.7 46.2 14.8 13.9 7.5 6.9 21.4 18.6 21.9 11.2 20.6 7.8 15.6 16.1 32.6 14.3 16.1 28.1 19.8 12.7 17.9 7.3 14.7 13.3 11.3 7.4 27.2 18.5 22.9 16.7 17.5 16.0 9.6 21.1 18.9 29.3 22.1 34.9 34.7 16.8 27.0 32.8 22.5 19.8 17.4 23.8 19.4 13.8 41.1 19.3 17.4 33.2 26.9 33.0 24.0 16.6 20.3 16.6 19.2 23.4 27.0 22.9 34.4 33.7 25.8 30.8 31.8 33.7 19.7 31.5 17.3 33.6 17.1 39.2 12.5 11.2 26.1 15.0 25.1 25.9 11.3 27.1 25.8 20.6 16.5 20.8 43.8 16.0 30.0 12.9 10.3 31.3 26.2 17.6 23.1 19.5 16.6 22.3 18.1 23.3 10.7 21.5 6.1 9.5 11.5 8.6 10.4 9.5 10.3 9.5 9.0 11.8 8.9 10.8 9.3 9.2 11.5 10.5 4.6 9.1 9.0 7.2 7.5 14.7 9.9 6.8 7.6 7.5 6.9 7.8 7.3 7.4 9.6 25.1 25.6 15.4 63.0 23.0 35.4 20.1 11.8 28.5 27.0 12.9 10.8 30.5 14.3 17.4 5.5 6.2 13.3 13.2 22.7 5.9 10.4 4.4 18.7 14.6 22.5 15.6 11.6 71.1 13.1 9.2 16.4 19.9 21.9 11.4 15.9 16.8 29.9 12.3 16.8 84.1 15.6 4.1 17.6 16.8 7.9 20.5 18.7 17.8 88.1 14.5 20.3 13.4 76.9 91.6 12.6 18.7 21.8 21.3 22.5 16.5 9.6 19.6 22.0 13.1 16.3 16.8 14.7 13.6 22.2 36.7 16.1 17.0 9.9 14.4 30.3 SEC31A "ABP125, ABP130, KIAA0905, SEC31L1" ENSG00000138674 "SEC31 homolog A, COPII coat complex component" O94979 4 82818509-82901166 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005457 Approved Supported Vesicles,Cytosol NA NA 40000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cytosol" "HPA005457: AB_1079896" "unprognostic (3.50e-2)" "unprognostic (2.28e-3)" "unprognostic (2.55e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavorable (3.32e-4)" "unprognostic (6.14e-3)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "unprognostic (4.21e-3)" "unprognostic (3.62e-1)" "unprognostic (1.64e-1)" "unprognostic (5.53e-3)" "unprognostic (2.92e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.69e-4)" 98.7 103.3 52.2 78.4 54.3 119.4 111.4 62.4 70.1 145.5 94.9 107.1 124.2 119.7 162.1 92.6 90.9 122.1 110.7 54.0 61.4 133.6 174.8 96.2 88.2 58.4 58.7 152.8 192.6 116.4 108.4 143.2 58.7 113.4 127.2 87.9 134.0 111.3 96.8 107.8 111.0 131.5 50.9 76.5 110.1 77.8 54.4 93.8 168.0 85.6 102.1 113.1 94.1 63.9 146.2 65.2 183.6 130.4 318.9 394.5 133.3 264.8 295.4 146.0 179.2 113.2 182.3 188.3 113.7 532.2 84.6 68.1 183.3 176.2 200.4 193.4 72.7 115.3 110.5 302.1 316.4 124.4 140.7 380.5 217.7 223.5 254.3 251.2 240.5 83.8 178.4 181.1 264.2 128.6 164.9 99.6 126.1 154.0 58.3 121.2 100.1 140.3 237.2 83.0 118.6 131.2 105.7 180.7 174.9 184.8 142.1 137.8 248.2 190.7 98.9 169.0 168.8 135.1 62.4 256.7 190.6 147.8 224.2 84.3 66.9 51.2 65.1 74.0 80.5 60.0 57.6 64.3 73.3 50.0 56.9 54.6 19.2 89.9 83.1 61.1 52.7 71.8 52.2 54.3 62.4 70.1 54.0 61.4 58.4 58.7 58.7 50.9 54.4 63.9 62.6 105.8 85.3 50.9 58.1 60.5 60.5 64.1 56.9 52.3 54.5 43.7 85.5 51.5 109.8 47.8 54.2 57.3 61.0 62.8 27.4 65.8 30.6 90.1 164.6 65.0 38.3 41.2 61.0 71.2 85.3 125.2 100.9 119.7 75.2 241.0 65.0 94.0 45.9 42.1 60.0 99.4 50.8 51.2 55.3 19.3 139.1 63.8 51.6 67.5 60.4 36.5 38.1 74.9 72.6 67.5 46.3 126.0 152.2 76.3 121.0 65.9 100.5 66.9 52.6 86.5 98.9 30.3 34.6 62.2 74.2 81.5 55.4 78.9 54.9 101.1 SECISBP2 SBP2 ENSG00000187742 "SECIS binding protein 2" Q96T21 9 89318500-89359663 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 332.4;Late spermatids: 440.3;Spermatocytes: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044314, HPA054905" Approved Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA044314: AB_10964885, HPA054905: " "unprognostic (1.07e-1)" "unprognostic (4.24e-1)" "unprognostic (1.64e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (1.21e-1)" "unprognostic (4.00e-1)" "unprognostic (8.80e-2)" "unprognostic (1.35e-2)" "unprognostic (7.18e-2)" "unprognostic (1.92e-2)" "unprognostic (1.16e-1)" "prognostic favorable (8.98e-9)" "unprognostic (5.44e-2)" "unprognostic (1.48e-1)" "unprognostic (1.98e-1)" "unprognostic (4.55e-3)" 22.9 27.2 17.7 22.6 21.0 35.1 28.2 22.2 19.9 29.2 25.1 26.0 23.5 27.4 28.0 19.7 28.1 18.6 18.2 18.5 21.3 31.6 29.2 25.9 31.9 19.4 18.7 40.8 40.8 25.3 28.1 27.1 19.6 25.2 27.5 49.0 27.1 16.3 41.6 29.7 29.3 15.3 17.8 34.8 27.0 68.9 19.9 33.8 35.3 21.3 27.5 24.7 23.6 28.0 29.9 19.9 53.5 31.1 24.7 26.5 38.8 16.9 20.9 19.8 19.4 11.2 24.4 44.4 14.6 15.9 31.5 37.1 36.4 17.0 18.3 29.4 21.6 21.8 16.5 28.7 21.3 44.2 31.5 16.7 31.5 16.8 19.9 21.8 25.0 58.5 28.4 51.1 19.1 27.7 60.9 22.6 55.7 74.5 19.5 29.1 26.2 29.3 22.2 22.7 39.0 38.3 15.3 33.7 45.9 35.4 29.9 37.8 23.2 19.2 22.3 26.0 26.4 61.7 42.3 18.2 33.3 28.3 28.1 17.0 8.2 14.7 10.8 8.9 10.5 14.2 10.9 10.7 7.4 14.8 16.2 13.9 23.0 10.2 11.5 13.0 14.3 6.5 17.7 21.0 22.2 19.9 18.5 21.3 19.4 18.7 19.6 17.8 19.9 28.0 72.5 44.8 58.0 43.8 81.2 19.5 72.0 29.9 38.1 113.8 49.0 59.8 18.3 31.5 40.2 40.5 91.8 70.6 67.7 41.0 43.0 39.4 332.4 44.8 34.6 46.2 37.3 60.4 55.2 31.4 47.2 36.1 42.8 47.7 36.1 51.8 36.0 36.9 26.9 57.2 55.4 56.7 30.5 32.6 19.4 440.3 40.0 69.6 21.4 51.5 47.2 44.8 69.0 46.8 77.5 35.9 49.6 25.6 81.5 64.1 49.2 54.5 41.8 112.9 32.9 63.2 36.3 338.9 223.2 44.2 25.4 91.8 54.3 43.9 50.0 65.4 SECTM1 K12 ENSG00000141574 "Secreted and transmembrane 1" Q8WVN6 17 82321024-82334074 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 90.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.4;Kupffer cells: 52.7;Macrophages: 36.8;Paneth cells: 48.2;Proximal enterocytes: 62.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 154.2" "Group enriched" "Detected in many" 13 "granulocytes: 154.2;monocytes: 58.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 83.3;BJ hTERT+: 86.7;BJ hTERT+ SV40 Large T+: 66.1;BJ hTERT+ SV40 Large T+ RasG12V: 64.4;PC-3: 70.2;SiHa: 122.5;SK-BR-3: 66.9;U-2197: 92.8" "Low region specificity" "Detected in some" HPA051214 Approved "Secreted to blood" NA NA 16000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA051214: AB_2732565" "unprognostic (2.42e-1)" "unprognostic (2.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.69e-2)" "unprognostic (4.29e-2)" "unprognostic (1.15e-2)" "unprognostic (4.55e-2)" "unprognostic (9.39e-2)" "unprognostic (3.17e-3)" "unprognostic (7.75e-3)" "unprognostic (2.10e-2)" "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.43e-1)" "unprognostic (4.31e-3)" "unprognostic (2.84e-1)" "unprognostic (1.01e-1)" 20.7 4.0 1.4 40.5 1.3 11.7 13.0 1.1 2.9 15.0 2.4 36.7 66.8 11.0 1.7 12.8 14.3 12.4 5.9 1.3 2.0 35.9 5.9 28.7 17.4 3.4 1.9 5.8 4.1 1.9 2.4 13.1 2.7 13.9 23.6 0.1 34.6 5.7 2.4 15.9 90.4 14.6 1.8 42.4 24.4 1.6 2.1 5.8 3.8 2.5 8.5 17.8 13.4 1.9 20.4 4.5 0.0 1.4 33.3 83.3 1.7 9.9 86.7 66.1 64.4 2.1 40.9 0.0 0.4 29.1 1.0 60.4 0.0 4.0 2.5 6.5 0.2 8.3 28.2 5.5 25.4 0.0 0.0 35.8 8.6 3.6 1.5 4.9 1.9 0.2 0.3 0.1 42.7 0.8 0.1 0.1 0.2 5.3 70.2 0.0 0.5 1.0 19.0 0.1 4.5 0.5 122.5 66.9 1.5 0.2 5.6 1.8 0.7 7.5 0.6 92.8 0.1 0.3 0.0 0.1 1.7 0.0 0.4 0.1 30.9 0.0 0.4 58.2 0.3 0.0 0.6 0.2 8.3 0.0 0.1 0.1 154.2 0.0 56.3 3.5 0.0 4.5 1.4 1.3 1.1 2.9 1.3 2.0 3.4 1.9 2.7 1.8 2.1 1.9 8.2 12.8 2.4 0.0 1.0 9.4 4.6 0.8 5.2 0.0 4.4 1.5 0.9 0.0 3.0 1.8 0.0 0.3 1.8 63.4 0.0 9.5 0.1 3.0 4.4 6.0 0.0 0.0 0.0 9.9 0.9 6.1 8.6 7.3 1.3 0.0 3.6 1.3 7.1 0.0 0.0 8.7 2.0 52.7 10.7 0.4 5.3 36.8 1.8 0.0 19.5 0.0 1.0 0.0 0.0 5.4 48.2 0.0 1.1 19.5 62.5 3.2 3.6 0.0 0.0 0.6 1.8 0.1 0.2 0.9 3.4 0.3 1.1 0.0 1.3 21.3 SEL1L "Hrd3, IBD2, SEL1L1" ENSG00000071537 "SEL1L adaptor subunit of ERAD E3 ubiquitin ligase" Q9UBV2 14 81471547-81533853 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "pancreas: 403.4" "Cell type enhanced" "Detected in all" "Plasma cells: 238.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 339.5;U-266/84: 313.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024267 Enhanced "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA024267: AB_1856659" "unprognostic (4.94e-1)" "unprognostic (8.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.91e-1)" "unprognostic (5.93e-2)" "unprognostic (1.16e-1)" "unprognostic (3.29e-1)" "unprognostic (2.78e-1)" "unprognostic (9.97e-2)" "unprognostic (2.58e-2)" "unprognostic (2.76e-3)" "unprognostic (4.86e-1)" "unprognostic (3.31e-2)" "unprognostic (1.30e-1)" "unprognostic (4.96e-2)" "unprognostic (1.83e-2)" "unprognostic (1.25e-2)" 30.6 19.1 13.9 31.1 17.8 17.7 25.2 17.0 17.0 21.4 11.5 35.7 36.7 24.2 18.1 16.8 17.1 22.0 22.8 14.5 17.4 28.8 66.6 27.6 21.6 18.9 16.7 17.1 403.4 29.9 8.7 38.4 19.3 31.6 31.8 15.7 19.6 22.8 22.2 15.5 32.5 28.1 18.4 30.6 35.0 11.2 17.6 17.8 54.3 21.1 29.3 29.0 12.1 25.9 35.3 69.3 27.4 35.5 60.2 58.6 48.5 54.6 52.3 31.2 33.0 26.6 53.7 36.0 58.8 63.2 38.1 32.8 19.2 30.6 56.1 56.0 13.6 26.3 21.7 33.2 86.0 53.6 60.3 47.8 72.0 31.4 68.0 45.9 51.7 29.5 16.2 195.2 38.6 42.7 30.6 15.1 8.7 58.7 29.6 21.2 38.9 28.4 24.0 54.1 15.5 25.7 42.7 39.4 44.9 23.5 68.5 35.5 86.8 87.7 49.0 49.2 34.1 339.5 313.1 35.4 96.5 24.1 34.4 31.5 19.7 24.8 16.8 25.6 13.7 14.2 12.9 13.4 18.9 13.1 12.0 12.9 45.7 16.7 22.5 13.7 14.0 14.5 13.9 17.8 17.0 17.0 14.5 17.4 18.9 16.7 19.3 18.4 17.6 25.9 51.6 12.8 35.2 27.1 44.8 26.8 19.0 27.1 15.9 23.5 31.5 18.9 67.0 32.9 24.9 27.6 31.3 23.5 44.1 48.8 5.9 24.1 3.5 21.1 48.9 40.0 21.6 15.4 35.9 45.6 21.9 44.7 37.8 28.0 34.2 32.0 38.9 125.7 31.9 30.3 35.2 38.9 50.8 58.1 40.4 5.4 23.6 47.6 53.4 29.0 39.7 18.3 30.9 42.3 70.7 40.1 33.1 28.2 238.9 40.0 34.8 20.2 27.8 18.3 46.0 28.5 51.8 14.0 18.8 16.0 26.1 41.9 32.9 38.9 32.0 33.9 SELENOF SEP15 ENSG00000183291 "Selenoprotein F" O60613 1 86862445-86914424 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 248.6;Ductal cells: 235.9;Extravillous trophoblasts: 338.3;Hofbauer cells: 241.2;Syncytiotrophoblasts: 315.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054937 Approved Nucleoli,Cytosol "Intracellular and membrane" No No 420000 "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoli Cytosol "HPA054937: AB_2682642" "unprognostic (6.15e-2)" "unprognostic (6.98e-3)" "prognostic favorable (6.53e-4)" "unprognostic (6.20e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (8.17e-4)" "prognostic unfavorable (1.98e-5)" "unprognostic (1.65e-1)" "unprognostic (6.51e-3)" "unprognostic (3.38e-2)" "unprognostic (3.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.79e-3)" "unprognostic (2.39e-2)" "unprognostic (1.09e-1)" "unprognostic (8.24e-3)" "unprognostic (1.34e-2)" 118.1 137.9 77.6 118.8 80.0 107.9 147.4 80.9 106.1 156.6 97.9 127.8 113.5 117.4 211.4 83.6 130.1 123.3 84.6 75.2 84.3 160.3 173.9 114.9 140.6 82.6 79.8 124.6 93.4 115.7 88.4 155.8 84.0 121.1 134.2 90.7 104.1 116.4 45.6 66.3 111.3 107.1 86.4 107.2 116.8 66.7 79.0 135.5 234.0 64.7 126.9 146.6 72.6 92.5 203.1 133.3 118.0 129.1 383.0 396.4 178.3 249.1 317.3 251.4 254.8 176.8 261.8 245.2 309.7 248.9 195.7 131.8 135.2 150.7 296.0 222.1 180.2 252.4 108.5 178.2 245.2 336.8 166.1 272.3 233.0 152.8 253.0 180.2 220.2 207.8 241.4 262.3 253.3 90.2 254.4 227.3 170.7 211.2 197.9 207.7 205.1 251.9 355.5 198.5 149.5 122.6 241.6 235.6 349.2 104.7 104.0 298.5 205.3 180.0 122.9 347.6 277.0 155.1 158.7 251.9 107.7 268.4 216.7 170.9 111.3 113.4 89.7 115.9 116.1 161.4 98.7 97.2 107.1 194.2 98.8 102.3 109.3 82.3 132.4 166.3 115.2 171.3 77.6 80.0 80.9 106.1 75.2 84.3 82.6 79.8 84.0 86.4 79.0 92.5 131.6 118.6 155.2 0.0 52.4 0.0 0.0 0.0 0.0 0.0 142.1 107.7 0.0 0.0 74.9 108.5 0.0 248.6 89.3 0.0 74.3 235.9 0.0 102.2 119.1 73.2 0.0 0.0 0.0 193.5 338.3 85.2 0.0 98.1 64.3 68.8 0.0 0.0 241.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 78.1 0.0 0.0 64.1 0.0 0.0 0.0 0.0 197.8 0.0 0.0 19.1 0.0 0.0 151.5 70.0 0.0 0.0 0.0 61.5 0.0 0.0 0.0 0.0 315.2 53.9 122.2 0.0 0.0 SELENOM "SELM, SEPM" ENSG00000198832 "Selenoprotein M" Q8WWX9 22 31104772-31120069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 373.6;Breast myoepithelial cells: 436.2;Collecting duct cells: 309.0;Distal tubular cells: 309.1;Endometrial stromal cells: 349.5;Exocrine glandular cells: 586.6;Smooth muscle cells: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 154.8;T-cells: 233.0" "Cell line enhanced" "Detected in many" "BJ: 152.2;BJ hTERT+: 143.8;HHSteC: 183.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008667, HPA019601" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 170000 "Cluster 20: T-cells - T-cell receptor" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "CAB008667: AB_1622762, HPA019601: AB_1856666" "unprognostic (5.29e-3)" "unprognostic (1.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.59e-3)" "unprognostic (1.45e-1)" "unprognostic (1.60e-2)" "unprognostic (1.60e-1)" "unprognostic (3.51e-3)" "unprognostic (8.31e-2)" "prognostic unfavorable (2.55e-6)" "unprognostic (1.32e-2)" "unprognostic (3.80e-1)" "unprognostic (5.20e-2)" "unprognostic (3.19e-2)" 241.8 95.4 126.7 55.7 126.7 2.9 239.8 127.3 170.7 458.8 189.9 575.4 37.2 600.2 14.8 86.1 437.8 28.6 227.2 130.0 149.3 162.5 36.7 157.5 25.9 137.1 138.6 262.4 154.3 94.7 241.1 32.2 131.0 339.6 16.4 8.1 198.8 140.1 109.9 114.8 193.9 85.3 139.6 97.6 285.6 42.1 142.1 10.2 225.8 18.6 15.3 462.3 290.7 132.3 12.8 25.7 7.4 42.7 68.8 80.5 82.2 152.2 143.8 69.2 50.0 0.8 2.0 1.6 30.9 89.9 31.2 1.2 6.9 9.2 4.7 7.0 25.6 2.7 7.8 13.3 183.7 0.0 13.1 78.5 27.1 33.1 12.6 33.1 9.0 2.2 2.4 14.7 17.9 6.6 0.5 1.4 9.6 11.8 27.3 0.1 0.1 18.1 11.1 0.1 16.2 35.7 47.3 41.6 0.7 2.5 57.5 0.9 30.9 20.8 59.0 77.8 0.1 13.2 6.5 1.0 83.1 0.2 13.8 18.3 10.5 5.1 105.3 19.9 137.9 154.8 174.5 127.0 6.4 129.5 233.0 137.8 8.2 39.1 40.1 2.5 179.0 102.6 126.7 126.7 127.3 170.7 130.0 149.3 137.1 138.6 131.0 139.6 142.1 132.3 168.6 54.5 126.5 0.0 38.8 0.0 0.0 0.0 0.0 0.0 373.6 436.2 0.0 0.0 32.2 309.0 0.0 11.7 23.2 0.0 309.1 101.2 0.0 22.8 349.5 61.8 0.0 0.0 0.0 586.6 149.5 161.3 0.0 18.1 30.3 30.8 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 42.9 0.0 0.0 0.0 0.0 166.2 0.0 0.0 22.3 0.0 0.0 152.5 20.4 0.0 0.0 0.0 225.6 0.0 0.0 0.0 0.0 23.4 24.8 30.5 0.0 0.0 SELENON "MDRS1, RSMD1, RSS, SELN, SEPN1" ENSG00000162430 "Selenoprotein N" Q9NZV5 1 25800176-25818221 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Desmin-related myopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 99.2;Exocrine glandular cells: 42.3;Granulosa cells: 31.2;Hofbauer cells: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058076 Approved Uncertain Cytosol "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA058076: AB_2683598" "unprognostic (2.65e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-1)" "prognostic favorable (2.23e-4)" "unprognostic (1.93e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (3.40e-5)" "unprognostic (1.94e-1)" "unprognostic (4.72e-1)" "unprognostic (3.32e-3)" "unprognostic (6.01e-2)" "unprognostic (3.07e-1)" "unprognostic (1.64e-1)" "unprognostic (1.53e-1)" "unprognostic (1.10e-1)" "unprognostic (5.56e-3)" "unprognostic (5.89e-2)" 65.7 48.0 51.6 34.0 51.2 17.0 60.8 45.5 53.3 43.8 74.2 42.5 17.4 48.8 19.5 36.5 40.2 30.1 60.7 49.6 48.5 52.5 20.3 51.8 20.5 72.8 55.2 51.7 60.1 37.0 40.2 38.9 52.1 58.2 20.8 11.7 45.7 39.6 56.3 30.2 31.0 56.2 54.1 43.4 43.4 12.0 62.6 13.6 53.8 39.7 16.3 46.9 35.6 50.2 52.6 49.5 160.9 138.4 102.5 178.8 54.4 62.2 93.4 67.7 53.9 12.9 54.2 0.1 40.4 94.6 74.8 49.9 42.4 66.2 51.1 55.8 32.6 51.4 18.2 16.0 73.8 11.0 116.6 191.7 43.8 71.0 35.5 79.9 214.4 17.4 18.5 7.2 64.7 26.8 2.3 15.7 61.0 40.9 33.7 45.4 70.3 6.4 27.7 14.8 33.5 56.9 39.4 35.3 52.7 43.0 35.6 36.1 180.5 68.4 46.2 126.6 37.1 5.8 0.2 1.4 94.8 15.9 84.4 2.7 1.2 1.6 0.7 1.0 0.4 0.7 0.6 0.5 0.8 0.4 0.9 0.6 0.2 0.3 1.1 0.1 0.7 0.4 51.6 51.2 45.5 53.3 49.6 48.5 72.8 55.2 52.1 54.1 62.6 50.2 99.2 9.6 10.3 0.0 2.0 0.0 0.0 0.0 0.0 0.0 23.0 19.3 0.0 0.0 3.7 20.2 0.0 16.4 3.8 0.0 0.0 18.6 0.0 6.5 22.4 21.5 0.0 0.0 0.0 42.3 11.4 12.5 0.0 13.5 2.5 31.2 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 3.1 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.9 0.0 0.0 14.9 3.6 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 13.0 2.2 8.6 0.0 0.0 SELENOO SELO ENSG00000073169 "Selenoprotein O" Q9BVL4 22 50200979-50217616 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 27.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 21.1;Granulosa cells: 34.7;Proximal tubular cells: 41.7;Theca cells: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071795, HPA079100" Approved Supported "Mitotic chromosome,Mitochondria" "Intracellular and membrane" Yes NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "Mitotic chromosome" "HPA071795: , HPA079100: " "unprognostic (1.79e-1)" "unprognostic (2.07e-3)" "unprognostic (1.60e-1)" "unprognostic (2.50e-3)" "unprognostic (3.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.85e-2)" "unprognostic (5.91e-2)" "unprognostic (1.51e-1)" "unprognostic (5.62e-2)" "unprognostic (8.20e-3)" "unprognostic (8.91e-2)" "unprognostic (1.81e-2)" "unprognostic (7.31e-2)" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "prognostic favorable (8.32e-4)" 6.7 6.7 2.3 4.5 3.4 13.9 4.8 11.7 6.8 5.6 2.5 5.3 8.0 5.9 2.8 8.2 5.7 4.1 5.3 3.0 1.1 6.6 27.9 4.7 6.4 4.6 2.7 5.0 13.1 3.0 4.1 3.0 3.7 5.6 2.0 2.9 7.7 4.1 12.3 8.2 6.5 2.4 2.3 6.5 7.0 3.7 3.1 4.4 5.1 4.1 3.9 5.1 6.1 6.0 12.0 7.7 4.2 4.7 5.6 4.1 8.6 11.8 5.6 7.0 5.5 10.6 7.5 7.9 9.2 4.7 3.9 26.2 6.5 10.7 1.4 2.3 29.9 5.7 17.4 6.4 2.8 10.6 6.9 5.4 7.2 4.5 3.5 4.5 5.8 5.3 7.8 5.6 2.9 18.6 5.7 16.4 3.7 2.8 15.6 17.6 5.9 11.8 4.3 15.3 8.4 9.3 12.8 11.3 7.5 2.1 8.7 7.5 9.5 6.0 8.3 6.5 7.1 13.8 3.6 4.7 6.8 6.9 3.5 0.0 1.1 1.3 0.2 0.4 0.5 0.0 0.2 0.5 1.1 0.2 0.1 0.4 0.5 0.0 0.4 0.4 0.2 0.3 2.3 3.4 11.7 6.8 3.0 1.1 4.6 2.7 3.7 2.3 3.1 6.0 11.8 0.0 21.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 13.3 13.2 0.0 0.0 5.6 9.2 0.0 3.1 12.2 0.0 15.6 3.6 0.0 11.8 10.9 3.0 0.0 0.0 0.0 4.6 2.4 6.0 0.0 15.2 3.8 34.7 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 2.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 4.5 0.0 0.0 41.7 3.6 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 1.9 5.5 29.6 0.0 0.0 SELENOP "SELP, SeP, SEPP, SEPP1" ENSG00000250722 "Selenoprotein P" P49908 5 42799880-42887392 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 2087.6;liver: 6268.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 448.7;Alveolar cells type 2: 529.3;Granulosa cells: 458.1;Hofbauer cells: 858.5;Macrophages: 373.3;Proximal tubular cells: 1044.7" "Cancer enriched" "Detected in all" 4 "liver cancer: 116.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Hep G2: 567.4;HSkMC: 451.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036287 Approved Uncertain "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA 2220000000 1800000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA036287: AB_10794618" "unprognostic (7.96e-2)" "unprognostic (2.10e-1)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (6.67e-2)" "unprognostic (6.37e-2)" "unprognostic (9.22e-2)" "unprognostic (2.19e-2)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "prognostic favorable (6.97e-6)" "unprognostic (1.35e-2)" "unprognostic (4.19e-2)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" 719.1 424.3 164.8 179.9 345.6 40.1 617.5 386.0 290.0 460.0 145.5 644.0 620.0 335.8 459.7 240.7 376.5 670.5 237.2 156.3 231.3 853.7 6268.1 512.0 552.4 519.4 316.4 701.2 229.0 246.0 108.3 973.0 490.3 214.2 714.2 59.2 170.8 374.1 156.4 171.8 2087.6 233.2 310.3 948.8 257.0 87.8 284.7 170.4 147.0 265.6 177.4 414.3 213.1 524.3 0.7 1.7 7.7 1.0 43.6 12.2 7.3 4.1 10.9 0.0 0.0 12.5 65.3 2.0 36.3 1.5 1.4 1.7 0.2 0.1 0.0 2.4 52.7 3.1 0.2 567.4 25.9 3.2 0.4 451.1 0.7 0.0 0.1 1.9 0.1 1.5 6.4 12.9 23.5 1.3 1.1 6.4 30.6 17.0 0.9 1.3 2.0 100.8 12.5 8.0 2.2 2.7 2.7 16.7 1.6 54.6 125.4 0.7 0.7 3.2 1.7 5.2 1.0 8.4 1.5 2.0 1.7 5.9 1.5 0.1 0.1 0.5 0.5 0.1 0.6 0.4 0.3 0.3 0.3 0.5 0.4 0.4 0.5 0.6 0.2 0.9 0.3 0.3 164.8 345.6 386.0 290.0 156.3 231.3 519.4 316.4 490.3 310.3 284.7 524.3 312.7 448.7 529.3 0.0 15.2 0.0 0.0 0.0 0.0 0.0 312.0 271.1 0.0 0.0 102.1 125.0 0.0 223.4 9.4 0.0 197.6 73.4 0.0 83.8 231.0 75.8 0.0 0.0 0.0 52.8 17.5 358.7 0.0 116.1 26.5 458.1 0.0 0.0 858.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 373.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 33.2 0.0 0.0 4.9 0.0 0.0 1044.7 52.5 0.0 0.0 0.0 133.1 0.0 0.0 0.0 0.0 112.9 10.0 361.8 0.0 0.0 SEMA3A "coll-1, Hsema-I, SEMA1, SEMAD, SemD" ENSG00000075213 "Semaphorin 3A" Q14563 7 83955777-84492724 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.6" "Cell type enhanced" "Detected in many" "Astrocytes: 58.4;Cone photoreceptor cells: 45.9;Excitatory neurons: 89.7;Rod photoreceptor cells: 66.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.5" "Lineage enriched" "Detected in single" 16 "monocytes: 1.5" "Cell line enhanced" "Detected in many" "AF22: 129.3;BJ: 102.9;fHDF/TERT166: 112.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029447, HPA052235" Approved Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA 1600000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA029447: AB_10602302, HPA052235: AB_2681770" "unprognostic (1.20e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (1.51e-1)" "unprognostic (5.82e-2)" "unprognostic (1.37e-2)" "unprognostic (5.98e-3)" "unprognostic (2.92e-3)" "unprognostic (6.05e-3)" "unprognostic (1.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.46e-1)" "unprognostic (4.44e-2)" "unprognostic (6.18e-12)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.61e-2)" "unprognostic (1.47e-4)" 6.8 0.2 3.8 3.8 5.8 0.1 1.5 0.6 3.0 4.4 0.0 9.8 1.4 1.0 2.2 5.8 1.6 5.6 2.5 2.0 0.7 0.4 0.4 2.3 3.3 3.8 0.2 0.4 0.4 0.5 2.1 10.4 4.6 2.9 5.7 22.6 0.4 0.4 0.1 1.1 2.4 4.7 0.6 3.8 2.0 1.2 0.3 0.5 1.7 0.5 1.6 5.4 0.6 4.4 11.8 32.8 129.3 0.1 3.8 3.1 8.4 102.9 60.0 8.5 5.3 11.4 30.7 0.0 4.8 112.0 1.1 57.0 0.3 24.6 11.8 0.0 4.2 0.0 6.0 0.0 3.3 2.6 0.0 3.9 0.0 18.1 4.4 26.2 32.1 0.1 0.1 0.2 3.4 0.6 0.0 0.0 48.6 0.5 11.6 2.3 55.3 3.4 18.5 0.8 9.8 5.2 0.8 0.2 1.1 20.7 0.6 1.1 18.3 11.2 11.6 32.6 15.1 7.6 5.5 0.0 11.5 4.5 22.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 3.8 5.8 0.6 3.0 2.0 0.7 3.8 0.2 4.6 0.6 0.3 4.4 1.0 3.2 1.7 58.4 0.0 0.9 0.0 15.4 0.0 15.1 0.2 0.3 6.0 0.0 22.4 0.0 45.9 0.4 0.3 0.1 0.0 0.1 0.2 2.0 0.7 7.3 0.0 0.0 89.7 2.0 0.2 9.3 0.0 9.0 1.3 3.5 1.8 0.1 1.0 3.3 10.0 0.0 2.0 0.3 2.7 0.2 2.5 0.5 1.8 7.5 0.0 19.6 0.0 9.5 5.8 5.5 0.0 0.0 0.0 0.3 0.0 0.0 15.6 66.3 0.0 1.5 2.1 1.7 1.9 0.4 1.3 0.3 1.1 18.6 0.0 0.2 SEMA3B "LUCA-1, SemA, sema5, SEMAA, semaV" ENSG00000012171 "Semaphorin 3B" Q13214 3 50267558-50277546 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 174.5;brain: 184.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 163.5;Distal enterocytes: 129.1;Gastric mucus-secreting cells: 208.0;Oligodendrocytes: 157.8;Proximal enterocytes: 336.4;Syncytiotrophoblasts: 111.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 73.7;Hep G2: 105.7;SK-BR-3: 54.5;WM-115: 173.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 27.9" HPA030651 Uncertain "Secreted in other tissues" NA NA 790000 "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 45: Enterocytes - Digestion" "HPA030651: AB_10602224" "prognostic favorable (1.27e-4)" "unprognostic (6.48e-2)" "unprognostic (5.40e-2)" "unprognostic (1.07e-1)" "unprognostic (1.68e-1)" "unprognostic (4.15e-1)" "unprognostic (1.89e-1)" "unprognostic (2.83e-2)" "unprognostic (2.21e-2)" "unprognostic (2.28e-1)" "unprognostic (1.85e-2)" "unprognostic (4.27e-1)" "unprognostic (7.99e-2)" "unprognostic (7.78e-2)" "unprognostic (3.89e-1)" "unprognostic (8.87e-3)" "unprognostic (1.69e-2)" 33.6 174.5 50.2 9.0 124.4 0.2 17.3 87.7 78.2 46.2 35.2 53.6 41.3 45.7 2.2 9.1 37.0 10.0 40.3 53.1 66.4 70.9 6.1 49.2 0.3 125.7 101.9 24.5 41.4 10.6 10.4 35.3 98.6 34.0 10.5 2.0 12.7 20.6 7.4 7.9 62.8 14.2 76.2 5.1 56.8 14.8 110.4 0.6 24.2 8.7 0.3 19.6 32.3 184.2 12.7 8.2 0.8 8.0 0.6 1.0 2.0 16.3 22.3 4.7 7.9 5.5 29.7 0.0 14.3 15.3 0.0 1.8 0.4 26.2 1.8 0.2 0.7 0.0 73.7 105.7 16.8 0.0 0.8 5.1 0.5 5.4 4.1 19.9 0.0 0.1 0.2 2.2 0.8 22.4 0.0 0.7 1.1 23.4 4.5 0.3 1.2 0.6 7.4 1.4 1.0 3.8 4.2 54.5 9.2 2.4 3.6 0.1 0.5 1.3 15.4 4.3 5.3 4.4 0.2 0.2 7.9 0.2 173.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.2 124.4 87.7 78.2 53.1 66.4 125.7 101.9 98.6 76.2 110.4 184.2 6.5 163.5 18.6 45.1 1.8 0.0 8.3 0.0 6.2 3.7 19.3 8.5 14.5 44.3 18.6 64.4 0.0 3.6 1.2 129.1 1.9 38.3 11.2 29.8 11.6 6.1 10.3 0.0 0.6 23.1 1.0 35.3 208.0 73.1 11.4 11.4 5.7 1.2 1.9 0.0 0.8 45.7 0.0 1.6 0.0 21.4 4.1 2.8 0.0 12.2 0.7 17.3 0.0 3.0 157.8 32.5 79.9 3.0 0.6 14.1 336.4 40.4 5.1 1.6 6.6 19.0 7.5 6.6 11.4 2.0 0.0 111.6 2.4 0.2 31.5 32.7 SEMA3C "SEMAE, SemE" ENSG00000075223 "Semaphorin 3C" Q99985 7 80742538-80922359 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 92.2;Breast myoepithelial cells: 93.5;Fibroblasts: 109.6;Ionocytes: 91.6;Oligodendrocytes: 223.7;Respiratory ciliated cells: 103.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 49.6" "Lineage enriched" "Detected in many" 9 "granulocytes: 49.6" "Cell line enhanced" "Detected in many" "GAMG: 252.7;RT4: 238.3;T-47d: 267.0;U-2197: 349.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042418 Approved "Golgi apparatus,Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 13000 "Cluster 46: Basophils - DNA binding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "HPA042418: AB_10797389" "unprognostic (1.93e-2)" "unprognostic (2.54e-3)" "unprognostic (4.94e-1)" "unprognostic (9.86e-2)" "unprognostic (6.74e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (9.28e-3)" "unprognostic (1.91e-3)" "unprognostic (1.39e-2)" "unprognostic (9.01e-2)" "prognostic unfavorable (4.08e-5)" "unprognostic (2.07e-2)" "unprognostic (1.55e-3)" "unprognostic (1.78e-2)" "unprognostic (1.57e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-2)" 53.8 9.5 4.9 12.7 8.1 0.8 57.3 9.1 5.5 53.0 2.6 38.4 10.6 42.7 23.1 20.5 15.4 30.0 22.1 11.0 12.7 10.0 1.3 18.4 1.0 15.0 8.0 48.5 2.6 0.8 3.7 6.0 17.5 66.6 31.3 1.0 27.3 42.3 19.3 17.9 14.1 44.4 10.0 22.2 20.6 12.9 8.4 1.4 1.8 34.3 1.1 69.8 14.4 12.8 6.6 77.0 156.4 0.6 35.2 82.5 0.3 51.8 59.7 25.9 32.5 12.4 144.7 0.0 2.1 17.7 252.7 31.2 0.7 47.0 42.4 0.1 15.8 9.9 63.6 0.7 41.3 0.7 0.2 36.1 32.3 63.6 62.0 220.2 0.5 0.0 0.5 0.1 46.4 113.7 0.2 0.3 1.4 22.2 12.2 0.1 75.5 1.2 142.9 238.3 0.8 82.4 145.7 38.9 9.5 66.3 267.0 0.2 125.2 140.1 64.2 349.2 93.9 1.2 0.0 0.1 52.8 0.0 142.3 49.6 5.7 0.9 0.0 2.4 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 2.6 0.0 1.9 3.3 0.0 1.7 4.9 8.1 9.1 5.5 11.0 12.7 15.0 8.0 17.5 10.0 8.4 12.8 7.4 9.6 8.9 3.3 0.3 26.4 41.8 92.2 10.8 0.3 15.8 93.5 38.2 1.5 39.8 7.3 6.2 0.5 1.7 56.1 1.9 3.8 0.5 20.3 11.9 7.7 6.0 4.6 41.7 6.6 1.3 109.6 17.9 34.4 5.1 13.2 1.1 0.0 8.8 0.0 16.7 15.7 91.6 3.1 14.9 2.3 7.8 9.0 55.2 20.6 8.3 1.5 1.0 3.0 223.7 68.2 12.4 52.3 0.0 53.7 12.5 0.4 103.0 0.6 0.0 38.8 17.3 0.7 2.7 3.0 18.9 0.3 1.5 9.9 30.4 70.0 SEMA3D "coll-2, Sema-Z2" ENSG00000153993 "Semaphorin 3D" O95025 7 84995553-85186855 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 47.8;thyroid gland: 45.4" "Cell type enhanced" "Detected in many" "Early spermatids: 157.4;Leydig cells: 52.5;Peritubular cells: 62.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 28.4;HaCaT: 28.7;TIME: 44.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037522 Uncertain Approved "Golgi apparatus,Plasma membrane" "Secreted in other tissues" NA NA 120000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus" "Plasma membrane" "HPA037522: AB_10672494" "unprognostic (7.05e-2)" "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (7.58e-3)" "unprognostic (4.02e-3)" "unprognostic (9.94e-2)" "unprognostic (5.62e-2)" "unprognostic (1.63e-1)" "unprognostic (9.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.26e-3)" "unprognostic (1.63e-1)" "unprognostic (2.75e-3)" "unprognostic (5.25e-3)" 3.2 2.9 5.9 1.0 1.9 0.0 5.9 0.8 4.6 5.6 0.0 2.8 1.8 2.4 2.6 1.7 5.1 1.7 2.2 6.2 4.7 3.8 1.0 3.6 3.3 2.3 8.9 1.9 0.7 0.2 0.5 0.7 2.2 8.3 3.4 2.2 4.3 1.9 0.0 2.4 3.3 1.4 3.0 47.8 3.3 3.8 3.2 0.3 45.4 0.9 1.4 3.1 0.7 3.2 0.0 0.0 12.1 0.0 0.0 0.0 0.5 7.6 8.2 8.8 4.2 0.0 0.0 0.0 2.2 28.4 0.2 28.7 3.1 0.0 5.8 0.0 5.8 0.0 3.1 0.0 0.1 0.0 0.0 0.1 0.0 1.5 7.2 10.1 13.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.6 7.5 2.1 8.9 6.8 2.8 0.0 0.1 1.1 0.0 0.0 0.4 13.8 0.4 0.0 44.2 0.0 2.7 0.4 0.0 5.4 3.4 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 1.9 0.8 4.6 6.2 4.7 2.3 8.9 2.2 3.0 3.2 3.2 2.8 0.0 3.3 18.3 1.8 3.6 2.4 0.1 0.0 2.6 0.8 8.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 157.4 1.6 0.3 14.8 26.5 0.0 12.3 0.2 0.0 15.3 0.0 4.3 2.5 0.2 2.9 0.0 1.3 1.7 5.1 0.7 2.0 0.0 5.7 23.3 52.5 0.5 12.4 19.7 0.0 1.9 0.0 3.0 0.9 0.0 0.0 62.4 0.0 5.8 1.9 4.7 0.8 4.1 0.0 0.7 2.0 0.7 0.8 0.1 2.4 0.0 0.5 11.2 1.0 0.4 SEMA3E "coll-5, KIAA0331, M-SemaK, SEMAH" ENSG00000170381 "Semaphorin 3E" O15041 7 83363238-83649139 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 110.2;Bipolar cells: 75.7;Excitatory neurons: 84.9;Oligodendrocyte precursor cells: 250.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 3.9;SK-BR-3: 19.9;U-2 OS: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029419, HPA063804" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA029419: AB_10602090, HPA063804: AB_2685127" "unprognostic (4.42e-2)" "unprognostic (1.48e-2)" "unprognostic (7.82e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-1)" "unprognostic (4.27e-2)" "unprognostic (9.36e-2)" "unprognostic (4.09e-2)" "unprognostic (3.25e-1)" "unprognostic (1.42e-1)" "unprognostic (9.09e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-6)" "unprognostic (1.32e-2)" "unprognostic (1.14e-1)" "unprognostic (7.17e-3)" "unprognostic (2.62e-1)" 1.2 0.1 3.1 0.2 2.8 0.0 2.8 0.6 2.3 1.8 0.1 2.1 0.6 1.9 0.3 1.2 0.6 2.3 0.1 5.0 5.3 0.1 0.1 2.2 0.0 1.6 4.3 0.1 0.4 0.0 0.2 0.2 1.3 4.3 1.7 3.9 2.2 3.3 0.2 0.5 1.2 1.1 3.2 0.0 1.3 0.0 4.3 1.7 0.6 1.0 0.1 3.2 0.7 3.7 0.2 1.1 0.2 0.0 0.5 3.1 0.0 0.0 0.2 0.2 0.3 0.0 0.3 0.0 0.0 0.0 0.5 0.0 3.4 0.0 1.3 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.9 0.0 0.0 0.5 0.4 1.1 0.0 2.0 0.0 0.0 0.8 0.1 0.0 0.0 19.9 0.0 3.2 1.6 0.0 0.0 0.7 6.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 2.8 0.6 2.3 5.0 5.3 1.6 4.3 1.3 3.2 4.3 3.7 10.5 176.3 110.2 2.9 0.2 1.1 1.3 1.6 0.0 75.7 19.0 7.5 1.7 18.6 43.2 1.8 0.0 0.8 0.2 0.1 0.0 3.9 1.1 3.8 1.2 10.7 0.0 0.0 84.9 1.1 0.4 21.3 3.1 9.3 24.0 0.2 0.0 0.3 0.1 0.0 12.3 0.0 4.1 1.0 2.1 0.0 0.9 3.6 1.8 1.0 1.0 29.6 0.0 250.3 6.0 6.2 0.0 0.0 0.3 2.6 0.1 0.5 35.7 3.6 0.0 0.8 1.0 0.3 0.6 0.3 0.4 0.3 2.8 0.0 0.0 2.5 SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 100.8" "Cell type enhanced" "Detected in many" "Adipocytes: 40.2;Bipolar cells: 23.4;Endothelial cells: 24.4;Hepatic stellate cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 108.1;HUVEC TERT2: 187.0;RT4: 112.3;SK-BR-3: 170.2;TIME: 338.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" NA NA 1700000 7900000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA035008: AB_10604091" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (1.87e-2)" "unprognostic (5.52e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.71e-1)" "unprognostic (9.05e-2)" "unprognostic (4.20e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.23e-2)" "unprognostic (6.19e-2)" "unprognostic (8.56e-2)" "unprognostic (3.88e-3)" "unprognostic (6.87e-3)" 33.8 9.0 8.8 8.6 5.7 2.7 31.9 5.1 8.1 28.3 12.0 10.5 13.4 14.5 5.4 100.8 15.6 10.8 22.6 5.0 9.2 49.2 4.8 46.2 3.7 10.2 12.7 3.6 6.7 5.5 11.1 30.4 8.7 32.7 6.3 22.0 24.6 32.5 10.4 75.1 12.5 9.1 6.3 50.7 17.3 2.4 21.8 6.1 27.1 6.1 12.6 27.0 55.4 4.7 13.9 3.1 0.7 14.2 0.2 1.3 3.0 8.0 24.2 6.5 10.2 5.4 6.1 0.5 77.9 1.1 0.7 47.5 6.9 100.7 2.4 0.1 1.8 0.8 108.1 18.5 5.7 1.7 3.2 6.2 55.3 15.1 45.4 90.7 187.0 1.2 2.9 0.1 1.3 12.4 1.5 7.5 8.6 6.2 10.1 11.8 0.0 0.5 7.2 112.3 1.1 2.6 12.8 170.2 0.3 10.4 67.2 7.3 338.6 4.2 31.9 29.7 5.5 0.2 0.0 0.9 0.3 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 5.7 5.1 8.1 5.0 9.2 10.2 12.7 8.7 6.3 21.8 4.7 40.2 0.0 1.1 0.0 0.2 6.8 3.0 9.2 5.7 23.4 10.7 6.0 9.2 1.5 6.6 18.4 10.4 11.2 0.6 5.5 0.0 0.3 0.0 6.5 2.4 24.4 0.0 0.0 0.7 0.8 0.5 1.1 16.3 6.9 0.0 0.2 25.4 0.6 1.4 6.7 1.1 10.7 0.0 0.3 0.8 0.3 0.3 0.2 0.0 3.7 0.0 8.7 0.0 0.0 0.1 6.8 3.8 0.0 0.0 2.5 5.7 0.7 5.4 19.8 0.0 0.5 2.5 0.0 0.4 17.7 8.9 6.3 0.4 0.2 5.2 8.6 SEMA3G "FLJ00014, sem2" ENSG00000010319 "Semaphorin 3G" Q9NS98 3 52433035-52445103 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 80.1;breast: 64.2" "Cell type enriched" "Detected in many" 6 "Adipocytes: 151.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "T-reg: 1.4" "Lineage enriched" "Detected in single" 15 "T-cells: 1.4" "Cell line enhanced" "Detected in some" "ASC diff: 26.1;Hep G2: 7.1;HUVEC TERT2: 7.4;THP-1: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001761 Uncertain "Secreted to blood" NA NA 5600000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA001761: AB_1079902" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "unprognostic (7.08e-2)" "unprognostic (1.47e-2)" "unprognostic (2.85e-1)" "unprognostic (5.79e-4)" "unprognostic (5.20e-3)" "unprognostic (9.14e-2)" "unprognostic (5.54e-2)" "unprognostic (5.64e-2)" "unprognostic (1.34e-3)" "unprognostic (4.14e-1)" "prognostic favorable (8.86e-5)" "unprognostic (5.63e-2)" "unprognostic (2.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.14e-1)" 80.1 1.9 9.9 3.4 9.4 0.1 64.2 18.9 11.4 5.1 6.2 6.8 3.0 5.9 1.3 4.5 5.2 5.9 18.6 8.4 9.0 19.8 1.3 23.9 1.6 10.8 10.0 3.2 3.1 1.8 2.4 26.7 11.3 4.6 3.7 0.4 10.6 2.5 12.8 12.7 9.6 3.9 9.9 8.0 5.7 1.3 12.1 1.7 7.7 18.6 1.8 8.3 7.8 9.1 0.0 0.1 0.1 0.2 26.1 0.2 2.5 0.0 0.0 0.0 0.0 0.7 0.3 3.3 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.2 3.9 0.2 7.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 7.4 2.6 0.0 0.4 0.0 0.3 0.2 4.3 1.2 0.7 0.1 0.0 0.0 4.1 0.0 0.3 0.5 0.5 0.0 0.4 0.5 0.1 1.9 6.5 2.9 0.1 2.4 0.0 0.0 0.5 2.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 9.9 9.4 18.9 11.4 8.4 9.0 10.8 10.0 11.3 9.9 12.1 9.1 151.5 3.2 1.3 0.0 0.3 0.4 0.1 0.1 0.0 1.7 5.1 5.5 10.7 0.0 0.0 3.7 0.0 1.7 0.9 0.3 0.0 0.0 3.0 2.8 1.6 20.4 9.6 0.0 0.0 0.0 0.2 3.6 1.1 5.8 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.3 5.0 0.3 0.5 0.0 24.4 0.0 0.5 0.0 0.0 0.0 0.0 0.1 1.2 0.2 0.0 9.4 0.0 0.1 0.2 0.0 4.1 3.0 0.1 0.1 0.5 0.1 7.5 0.4 0.1 0.2 0.0 SEMA4A "CORD10, FLJ12287, SEMAB, SemB" ENSG00000196189 "Semaphorin 4A" Q9H3S1 1 156147366-156177752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Angiogenesis, Differentiation, Immunity, Neurogenesis" "Developmental protein" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 51.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 63.7;Plasma cells: 61.2;Skeletal myocytes: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 123.9;eosinophil: 120.2;intermediate monocyte: 132.7;myeloid DC: 183.0;neutrophil: 210.7;non-classical monocyte: 76.1" "Group enriched" "Detected in all" 13 "dendritic cells: 183.0;granulocytes: 210.7;monocytes: 132.7" "Cell line enhanced" "Detected in many" "Karpas-707: 151.8;U-698: 67.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069136 Supported NA NA 3300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA069136: AB_2686093" "unprognostic (1.90e-1)" "unprognostic (2.39e-2)" "unprognostic (4.24e-1)" "unprognostic (5.20e-2)" "unprognostic (8.04e-2)" "prognostic favorable (1.09e-4)" "unprognostic (1.97e-1)" "unprognostic (2.50e-2)" "unprognostic (3.51e-1)" "unprognostic (1.60e-2)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (8.20e-4)" "unprognostic (8.77e-2)" "unprognostic (4.63e-2)" "unprognostic (6.06e-2)" "unprognostic (1.28e-2)" 6.1 1.0 22.7 24.8 21.5 37.5 9.1 6.1 23.2 10.8 4.7 6.9 3.6 3.0 51.3 32.5 7.9 8.8 3.0 25.3 23.0 18.1 2.1 15.2 31.5 12.2 15.5 5.2 4.0 1.5 3.6 1.8 15.3 16.3 6.1 2.0 19.2 12.5 3.1 32.3 4.8 3.6 11.4 26.9 10.6 4.1 29.0 8.1 23.1 2.2 33.1 10.8 17.4 13.1 12.6 0.0 0.5 0.0 0.0 0.9 0.3 0.2 0.4 0.1 0.2 0.1 0.3 8.1 0.3 0.6 0.1 11.7 0.9 10.0 0.4 3.5 0.0 0.4 0.2 0.4 0.4 18.5 1.1 0.6 9.2 0.2 0.4 2.3 0.9 2.8 1.3 151.8 0.5 15.2 0.1 6.5 3.6 12.4 0.0 0.6 0.3 5.4 17.9 24.1 0.1 0.3 0.0 19.2 1.0 1.7 22.3 23.3 0.9 0.0 0.1 0.0 0.0 29.3 3.0 67.6 0.5 17.5 0.4 16.0 123.9 120.2 4.0 132.7 8.5 13.2 1.3 8.0 183.0 10.9 0.2 1.3 210.7 4.3 76.1 25.7 1.4 66.4 22.7 21.5 6.1 23.2 25.3 23.0 12.2 15.5 15.3 11.4 29.0 13.1 13.6 19.2 63.7 25.8 13.9 23.5 22.5 25.8 24.5 1.9 28.3 27.6 5.9 14.3 13.8 40.5 0.0 0.9 9.8 6.5 1.9 6.1 6.4 12.9 21.6 9.5 3.6 1.3 7.5 0.7 0.4 20.9 22.4 33.5 17.7 0.6 9.3 0.6 15.4 0.0 5.2 24.1 8.2 22.8 42.1 4.3 1.8 37.8 16.0 1.0 32.6 6.3 2.1 1.0 1.0 1.1 7.2 1.2 61.2 14.2 0.8 0.7 9.6 0.4 0.0 100.1 11.3 3.1 0.7 39.0 27.6 1.8 10.0 1.4 17.6 15.6 SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 16.9;naive B-cell: 14.9;neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CAPAN-2: 182.4;RPTEC TERT1: 111.1;RT4: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" 11.9 37.6 20.3 18.0 21.9 9.8 22.5 18.8 21.6 35.1 12.8 50.2 30.2 17.1 8.2 124.4 22.6 17.1 24.9 17.3 21.0 47.7 43.2 20.5 12.0 23.5 24.0 21.6 38.5 18.1 18.6 18.3 21.4 31.4 12.1 27.1 41.2 17.6 7.8 50.9 34.7 13.3 21.0 30.3 32.2 10.7 22.9 13.2 34.2 7.9 13.0 42.2 59.8 26.8 21.2 56.3 4.2 13.2 3.8 2.6 30.4 6.4 13.9 7.8 8.3 7.0 182.4 14.9 69.2 4.7 45.0 97.8 3.7 91.2 6.4 85.4 11.7 19.7 13.5 9.4 15.1 2.6 8.7 10.8 39.1 8.5 17.5 32.5 8.8 4.4 9.6 23.0 4.3 15.6 5.4 8.4 18.7 46.8 51.1 6.4 3.1 33.1 111.1 124.0 13.3 13.5 22.3 35.4 8.5 9.3 24.7 6.0 20.0 6.3 11.4 13.1 14.5 33.0 43.2 7.5 58.8 16.1 6.3 0.0 2.4 0.3 0.9 1.4 0.6 16.9 0.5 0.5 1.2 14.9 0.5 0.6 5.1 0.4 2.8 0.2 0.2 1.5 20.3 21.9 18.8 21.6 17.3 21.0 23.5 24.0 21.4 21.0 22.9 26.8 1.8 16.0 22.5 67.3 29.2 65.0 40.0 51.4 23.9 5.7 29.1 18.9 7.8 8.6 44.6 16.5 25.0 13.9 2.4 47.8 3.9 27.3 0.9 15.6 19.6 4.4 4.2 4.0 23.5 35.5 74.5 6.4 34.1 28.3 0.0 8.6 4.6 16.8 13.3 16.8 28.2 17.5 18.3 6.9 7.5 1.2 13.1 5.5 5.4 2.8 5.3 25.1 1.0 8.0 8.3 44.7 26.1 12.0 8.0 46.9 19.6 4.5 22.6 48.3 19.7 5.7 15.3 0.7 3.2 65.3 57.1 12.4 4.3 5.2 20.2 52.0 SEMA4C "Semacl1, Semaf, SEMAI" ENSG00000168758 "Semaphorin 4C" Q9C0C4 2 96859718-96870757 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 137.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "BEWO: 298.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011090 Approved NA NA 700000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA011090: AB_2185705" "unprognostic (1.25e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (3.53e-5)" "unprognostic (7.10e-2)" "unprognostic (4.46e-2)" "unprognostic (1.57e-2)" "unprognostic (4.20e-3)" "unprognostic (3.08e-1)" "unprognostic (2.16e-1)" "unprognostic (3.56e-2)" "unprognostic (1.82e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (9.50e-7)" "unprognostic (4.78e-3)" "unprognostic (3.09e-1)" "unprognostic (7.31e-2)" "unprognostic (4.08e-1)" 21.3 8.9 11.5 11.3 24.2 3.0 17.7 16.8 19.9 29.0 0.5 42.1 7.4 37.2 6.0 14.0 33.3 15.3 20.2 11.8 15.6 14.9 13.3 14.4 9.8 24.9 21.1 23.1 9.4 7.1 10.2 41.8 21.0 20.8 5.7 7.0 16.5 20.6 7.5 15.9 14.6 19.3 18.7 28.5 15.1 2.7 19.0 6.5 12.3 13.4 5.3 32.3 22.3 39.1 8.0 11.7 35.6 39.7 8.4 10.5 298.5 13.9 17.4 13.4 13.5 11.8 13.3 0.0 22.3 8.5 13.3 8.1 10.2 6.9 6.5 15.2 11.8 5.4 10.5 22.2 19.2 2.2 13.7 16.1 5.4 12.3 10.4 14.9 9.9 2.6 36.5 11.6 12.7 41.0 0.1 17.4 49.1 0.4 10.6 12.5 20.0 13.8 4.8 17.1 22.4 32.4 11.2 24.6 60.8 27.6 8.7 21.4 3.1 21.9 27.3 30.9 14.6 0.2 1.0 0.1 10.6 17.2 37.1 0.5 0.0 0.0 0.6 0.2 0.8 0.0 0.2 0.4 0.0 0.0 0.4 0.1 0.0 1.4 1.5 0.8 0.3 0.4 11.5 24.2 16.8 19.9 11.8 15.6 24.9 21.1 21.0 18.7 19.0 39.1 28.1 0.0 10.3 15.3 1.1 11.5 7.9 7.6 18.2 32.2 9.9 8.3 6.9 12.8 8.6 5.5 10.4 46.8 9.7 1.8 1.9 9.7 0.5 7.4 15.8 26.6 5.4 2.1 7.2 5.0 137.3 17.3 3.1 11.6 1.3 10.2 23.9 9.8 7.9 15.2 4.1 5.7 6.1 4.4 6.1 1.5 13.4 9.2 21.4 18.7 3.2 23.6 12.3 4.5 35.5 10.5 1.2 9.1 3.6 9.4 0.1 0.8 7.4 38.8 19.7 11.4 24.1 0.6 4.2 13.0 10.2 45.0 9.5 4.9 3.9 4.8 SEMA4D "C9orf164, CD100, coll-4, FLJ39737, SEMAJ" ENSG00000187764 "Semaphorin 4D" Q92854 9 89360787-89498130 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 260.2" "Cell type enhanced" "Detected in many" "dendritic cells: 76.5;NK-cells: 92.7;Oligodendrocytes: 310.5;T-cells: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 133.2;HMC-1: 97.2;JURKAT: 89.1;MOLT-4: 120.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015662, HPA023277" Approved NA NA 7500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA015662: AB_1856671, HPA023277: AB_1856672" "unprognostic (2.94e-2)" "prognostic favorable (4.17e-4)" "unprognostic (1.12e-2)" "unprognostic (8.22e-2)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (1.27e-1)" "unprognostic (1.58e-1)" "unprognostic (7.79e-2)" "unprognostic (2.74e-1)" "unprognostic (3.18e-3)" "unprognostic (1.50e-2)" "unprognostic (2.29e-3)" "unprognostic (3.05e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-1)" "prognostic favorable (4.06e-5)" 7.2 12.8 73.5 35.1 149.7 28.7 6.1 129.0 122.7 9.1 34.2 10.4 10.6 6.5 12.2 27.3 11.0 12.3 12.1 72.0 88.4 32.0 4.1 14.2 62.4 165.2 145.6 6.5 8.0 6.0 13.8 5.5 147.8 11.9 9.7 5.0 12.0 6.6 88.0 17.4 28.9 5.5 119.1 51.3 16.7 10.6 127.0 43.4 11.8 27.5 49.8 11.4 16.2 260.2 12.7 9.2 8.4 12.4 0.4 0.8 19.0 1.1 0.5 2.6 1.7 6.1 13.8 47.3 5.1 0.2 9.7 6.4 7.5 3.6 1.1 133.2 7.5 20.1 3.3 0.7 1.5 26.4 97.2 0.3 2.8 0.6 0.3 0.3 4.9 89.1 4.8 31.5 0.0 20.9 120.9 33.9 20.6 25.0 0.5 38.2 2.8 13.4 16.5 13.0 19.7 13.1 3.4 8.9 0.3 11.7 10.1 14.4 3.2 0.1 7.6 1.0 6.1 34.9 16.3 6.6 6.0 32.1 7.6 17.2 7.5 38.2 22.0 7.0 13.3 4.3 17.5 18.6 2.6 2.5 19.9 23.2 37.0 9.4 8.1 8.0 17.7 14.5 73.5 149.7 129.0 122.7 72.0 88.4 165.2 145.6 147.8 119.1 127.0 260.2 3.4 6.4 15.7 33.6 35.4 4.6 3.3 2.1 3.4 12.4 9.5 5.5 18.7 5.7 6.9 11.0 2.1 9.0 76.5 1.5 3.9 5.4 2.2 10.9 6.4 5.2 1.8 23.1 44.5 3.3 2.1 6.7 7.7 15.4 42.5 8.0 5.3 1.6 21.6 33.7 17.2 6.3 4.1 28.2 6.1 3.8 7.5 37.4 1.8 49.6 43.7 8.9 92.7 12.1 310.5 3.7 0.7 15.1 53.7 6.5 0.5 14.2 5.7 5.1 0.0 11.4 2.6 0.9 26.1 7.1 5.4 3.7 89.7 2.3 3.3 7.7 SEMA4F "SEMAM, SEMAW" ENSG00000135622 "Ssemaphorin 4F" O95754 2 74654228-74683853 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 44.5;Inhibitory neurons: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064095, HPA065969" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Plasma membrane, Centrosome" "HPA064095: AB_2732710, HPA065969: AB_2685590" "unprognostic (9.69e-2)" "unprognostic (8.88e-3)" "unprognostic (1.58e-2)" "prognostic unfavorable (5.94e-5)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.23e-2)" "unprognostic (1.61e-3)" "unprognostic (6.95e-2)" "unprognostic (9.01e-3)" "unprognostic (6.53e-2)" "unprognostic (2.21e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.74e-6)" "unprognostic (2.60e-2)" "unprognostic (8.08e-2)" "prognostic favorable (6.94e-4)" "unprognostic (4.69e-2)" 3.2 2.3 5.4 0.9 7.0 0.4 3.2 3.2 8.2 4.1 0.1 2.5 0.5 3.6 1.7 1.3 3.3 0.8 2.7 8.0 6.3 3.5 1.0 2.5 1.5 4.2 2.1 5.3 2.6 3.0 7.2 0.9 3.9 3.1 1.0 4.7 2.7 1.4 1.4 1.9 2.1 1.6 1.5 2.6 2.2 4.1 8.1 1.2 3.1 1.3 1.4 2.6 3.2 3.8 6.1 3.4 3.7 5.5 5.8 3.3 2.6 3.9 8.9 7.4 6.5 1.4 3.3 2.3 5.0 6.2 14.4 1.9 6.7 5.7 7.5 5.3 7.0 4.4 1.4 3.8 2.3 1.0 5.4 2.6 6.0 4.9 2.4 14.1 2.9 4.4 0.2 0.2 4.8 2.1 3.3 0.8 2.6 2.7 4.0 0.0 5.4 0.0 6.0 2.6 2.9 5.8 7.0 1.8 6.5 5.0 2.6 0.7 4.9 11.5 5.8 2.9 7.1 5.2 5.6 0.3 13.4 0.3 5.6 0.3 0.1 0.7 1.9 0.0 1.2 1.1 1.1 1.7 0.0 0.8 1.1 1.3 0.3 1.0 0.2 0.0 0.9 0.8 5.4 7.0 3.2 8.2 8.0 6.3 4.2 2.1 3.9 1.5 8.1 3.8 2.2 0.0 6.5 4.9 2.7 0.4 1.8 1.8 2.2 8.8 1.8 2.5 2.4 5.7 4.8 5.5 12.5 0.8 1.4 0.7 1.9 2.1 3.2 0.6 0.6 2.2 7.2 0.8 44.5 1.6 2.4 3.3 1.5 1.0 2.5 3.0 3.3 0.6 0.8 11.8 22.7 0.6 2.0 0.0 0.7 3.7 0.9 0.7 0.0 4.7 1.5 3.3 4.1 4.5 5.8 2.7 1.4 1.5 0.7 1.3 0.4 0.3 1.3 6.7 6.6 3.1 1.4 5.6 11.2 0.5 0.4 0.4 3.5 0.5 1.0 1.6 SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969518-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 84.6;liver: 102.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 66.4;Gastric mucus-secreting cells: 27.0;Hepatocytes: 60.5;Intestinal goblet cells: 34.6;Paneth cells: 38.5;Proximal enterocytes: 47.6;Undifferentiated cells: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 31.7;CACO-2: 30.5;Hep G2: 113.8;OE19: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" NA NA 1300000 "Cluster 37: B-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (3.90e-3)" "unprognostic (9.43e-3)" "unprognostic (2.84e-1)" "unprognostic (1.13e-2)" "unprognostic (5.55e-2)" "unprognostic (8.11e-2)" "unprognostic (3.28e-1)" "unprognostic (3.71e-2)" "unprognostic (3.63e-1)" "unprognostic (1.41e-2)" "unprognostic (3.09e-2)" "unprognostic (3.14e-1)" "unprognostic (3.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.05e-2)" 2.4 12.7 13.1 5.9 10.9 0.4 3.6 18.9 12.3 6.9 12.8 53.6 53.4 3.5 32.1 3.6 5.9 9.0 3.0 10.0 11.6 19.1 102.4 5.8 2.5 11.2 14.4 18.9 31.3 7.3 9.9 3.9 11.5 20.2 84.6 7.3 8.5 3.0 2.6 18.3 41.2 4.6 9.6 3.1 20.9 3.7 17.0 0.8 15.3 0.8 0.9 4.0 5.0 9.9 0.2 31.7 8.0 3.4 5.0 1.6 6.8 1.2 3.4 1.7 1.7 30.5 5.2 0.5 4.2 1.5 0.6 2.1 8.0 1.4 1.4 0.7 4.9 1.7 3.0 113.8 12.5 1.2 1.0 8.3 1.8 1.6 0.9 22.2 4.4 3.5 3.3 0.4 2.5 2.0 0.5 1.2 1.3 69.1 1.8 3.1 0.7 1.5 7.4 1.0 2.5 12.5 1.1 2.1 3.2 8.7 8.7 1.5 3.0 1.0 3.7 0.8 0.3 1.1 0.6 0.5 0.9 1.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 10.9 18.9 12.3 10.0 11.6 11.2 14.4 11.5 9.6 17.0 9.9 0.3 3.2 1.1 3.9 1.2 0.0 0.6 0.7 0.6 3.5 2.5 2.0 1.2 20.0 0.2 0.0 0.0 8.8 0.0 66.4 0.0 2.7 0.2 1.6 0.7 0.6 8.5 0.8 3.0 2.6 1.9 2.0 27.0 0.3 0.0 3.4 2.2 60.5 0.9 11.8 14.1 34.6 2.0 3.3 0.0 0.2 2.1 0.2 1.8 0.0 0.0 0.9 0.0 3.5 5.5 2.4 38.5 1.2 0.2 3.0 47.6 6.4 2.4 1.6 0.0 0.1 0.4 1.1 1.9 0.5 0.1 2.9 0.2 12.7 45.9 0.9 SEMA5A "SEMAF, semF" ENSG00000112902 "Semaphorin 5A" Q13591 5 9035033-9546075 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 1189.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 64.2;fHDF/TERT166: 37.1;RT4: 66.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004632 Approved NA NA 13000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 68: Oligodendrocytes - Mixed function" "HPA004632: AB_1079905" "unprognostic (1.48e-1)" "unprognostic (1.68e-2)" "unprognostic (1.40e-2)" "unprognostic (6.67e-2)" "unprognostic (3.65e-1)" "prognostic favorable (2.45e-4)" "unprognostic (7.02e-2)" "unprognostic (1.75e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.10e-2)" "unprognostic (8.15e-2)" "prognostic favorable (3.66e-8)" "unprognostic (8.51e-3)" "unprognostic (1.27e-2)" "unprognostic (3.57e-1)" "unprognostic (3.01e-2)" 4.6 1.2 7.8 2.7 9.1 0.0 6.8 5.6 23.6 13.0 3.6 9.5 2.9 8.9 2.2 3.1 2.9 5.4 9.5 35.4 17.0 11.6 4.9 11.1 4.7 10.9 11.1 1.7 4.4 1.9 2.3 7.0 17.1 2.9 7.5 7.0 2.1 4.9 1.3 4.4 5.3 2.4 8.3 6.3 1.9 1.6 16.4 1.7 1.9 3.1 3.7 5.8 3.8 13.4 0.0 0.0 15.0 0.0 10.1 14.1 0.0 24.2 64.2 4.7 2.5 0.0 0.1 0.0 0.0 37.1 0.3 21.6 0.0 1.4 2.4 0.0 0.2 0.0 0.1 0.0 1.4 0.0 0.1 3.6 0.7 5.3 21.6 10.5 0.0 0.0 0.0 0.0 5.7 0.7 0.0 0.0 1.5 13.2 1.1 0.0 0.0 0.9 1.8 66.7 3.1 0.3 0.2 0.0 19.9 5.1 0.0 0.0 0.0 23.0 0.5 0.0 0.5 0.0 0.0 0.0 21.4 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 7.8 9.1 5.6 23.6 35.4 17.0 10.9 11.1 17.1 8.3 16.4 13.4 8.0 150.6 5.6 63.6 0.3 9.2 6.4 30.8 8.0 2.8 1.6 49.0 37.0 22.8 14.3 1.8 0.0 1.8 9.6 23.9 0.0 3.4 32.6 6.3 151.5 6.4 5.4 0.0 60.6 2.3 1.2 27.8 0.5 9.3 1.3 1.8 5.3 4.3 1.3 247.3 53.1 10.9 0.0 0.0 5.2 50.5 10.2 0.8 33.8 134.9 0.1 44.8 0.0 1189.7 152.3 1.2 8.0 14.7 0.0 8.2 16.9 14.4 2.0 3.6 39.5 4.3 40.5 0.6 0.5 11.4 4.8 1.9 1.4 29.0 20.5 14.1 SEMA5B "FLJ10372, KIAA1445, SEMAG, SemG" ENSG00000082684 "Semaphorin 5B" Q9P283 3 122909082-123028605 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.2" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Excitatory neurons: 30.8;Muller glia cells: 7.3;Oligodendrocyte precursor cells: 45.2;Smooth muscle cells: 14.3" "Cancer enhanced" "Detected in many" "renal cancer: 18.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 79.7;NTERA-2: 15.7;SH-SY5Y: 21.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066548 Enhanced Supported Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA066548: AB_2685689" "unprognostic (7.34e-2)" "unprognostic (1.84e-3)" "unprognostic (1.92e-4)" "unprognostic (3.01e-2)" "unprognostic (1.04e-1)" "unprognostic (2.28e-1)" "unprognostic (4.72e-2)" "unprognostic (1.58e-2)" "unprognostic (7.66e-3)" "unprognostic (2.87e-2)" "unprognostic (4.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (1.31e-3)" "unprognostic (5.96e-2)" "unprognostic (6.12e-2)" "unprognostic (2.12e-1)" 1.7 1.5 12.1 0.4 11.8 0.0 1.3 7.3 15.9 1.8 6.7 1.3 0.9 1.4 2.8 0.7 3.5 2.5 9.5 16.2 8.0 9.1 0.9 1.2 0.6 8.4 8.5 1.4 1.7 0.6 2.7 2.6 9.7 1.4 0.8 7.1 0.4 1.4 0.9 1.5 1.5 1.9 7.7 0.2 0.6 0.7 7.8 0.2 2.6 0.5 0.6 1.6 1.6 10.9 0.0 0.0 79.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 21.3 0.0 0.2 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 11.8 7.3 15.9 16.2 8.0 8.4 8.5 9.7 7.7 7.8 10.9 1.2 0.0 1.1 9.4 0.0 0.0 0.0 0.1 0.0 7.2 0.1 0.0 3.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.8 0.0 0.0 30.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 1.8 0.0 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.9 0.6 7.3 0.0 45.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 14.3 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SEMA6A "HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ" ENSG00000092421 "Semaphorin 6A" Q9H2E6 5 116443555-116574823 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 60.1;brain: 75.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 128.9;Hepatic stellate cells: 145.6;Horizontal cells: 138.0;Oligodendrocyte precursor cells: 138.7;Oligodendrocytes: 311.3;Syncytiotrophoblasts: 348.1" "Cancer enhanced" "Detected in all" "testis cancer: 20.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 44.3;HAP1: 52.0;NTERA-2: 115.2;SuSa: 221.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031264, HPA031265, HPA031267" Approved Approved "Nucleoplasm,Nuclear bodies,Intermediate filaments" NA NA 620000 "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Nuclear bodies, Intermediate filaments" "HPA031264: , HPA031265: AB_10610423, HPA031267: " "unprognostic (3.79e-2)" "unprognostic (3.91e-1)" "unprognostic (1.82e-2)" "unprognostic (6.81e-2)" "unprognostic (2.69e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.39e-4)" "unprognostic (1.64e-1)" "unprognostic (4.71e-2)" "unprognostic (5.82e-2)" "unprognostic (1.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.62e-3)" "unprognostic (1.92e-1)" "unprognostic (6.21e-3)" "unprognostic (7.32e-3)" 13.4 60.1 24.1 4.9 48.6 3.5 13.1 39.9 31.9 10.0 0.3 20.6 19.9 6.0 2.8 4.4 8.2 12.9 7.1 24.5 40.3 8.6 5.6 17.9 4.5 51.9 41.0 18.1 11.2 2.0 5.8 31.9 50.0 6.0 17.5 10.4 16.6 2.5 8.2 6.9 25.5 5.8 32.9 11.2 7.0 7.5 44.1 3.6 9.1 6.5 2.2 5.6 8.1 75.2 0.3 0.1 36.9 44.3 0.2 0.0 38.2 0.7 0.4 0.2 0.2 2.2 1.5 1.6 1.7 0.6 0.7 0.4 52.0 0.0 0.1 1.6 7.7 0.7 0.7 13.1 0.5 0.5 2.6 0.7 0.0 0.0 0.0 0.5 0.2 0.3 0.3 0.4 0.2 0.8 0.7 3.9 115.2 0.2 0.3 6.9 24.2 1.8 19.0 33.7 10.3 3.7 0.2 0.7 19.7 221.1 14.4 2.6 0.9 3.6 3.1 0.4 1.5 0.6 0.7 0.8 0.6 1.8 13.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.1 48.6 39.9 31.9 24.5 40.3 51.9 41.0 50.0 32.9 44.1 75.2 64.7 0.0 0.6 71.8 1.1 6.5 0.7 13.1 34.7 17.9 17.0 8.3 8.6 61.5 3.1 14.7 2.1 128.9 0.3 73.3 0.0 42.9 13.6 12.2 4.8 60.9 28.1 2.7 26.9 1.3 8.1 15.4 1.1 10.6 0.0 9.7 145.6 0.9 12.5 138.0 62.2 30.7 0.0 14.8 4.6 2.4 6.5 1.1 24.9 54.4 0.1 5.8 0.0 138.7 311.3 2.0 46.7 1.9 2.6 1.5 40.7 4.4 0.6 3.5 0.0 36.1 8.1 0.9 1.5 11.3 4.1 348.1 0.8 3.5 40.3 2.2 SEMA6C KIAA1869 ENSG00000143434 "Semaphorin 6C" Q9H3T2 1 151131685-151146664 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 322.9;tongue: 96.9" "Cell type enhanced" "Detected in many" "Adipocytes: 12.9;Cardiomyocytes: 19.1;Cone photoreceptor cells: 20.9;Inhibitory neurons: 13.7;Skeletal myocytes: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.1;HUVEC TERT2: 24.8;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA076150, HPA077625" Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1500000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "Nucleoli fibrillar center, Cytosol" "HPA076150: , HPA077625: " "unprognostic (6.97e-2)" "unprognostic (8.40e-2)" "unprognostic (1.56e-3)" "prognostic unfavorable (3.27e-4)" "unprognostic (2.79e-1)" "unprognostic (2.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" "unprognostic (4.25e-2)" "prognostic favorable (3.06e-5)" "unprognostic (3.72e-2)" "unprognostic (1.67e-2)" "unprognostic (6.12e-2)" "unprognostic (9.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" 8.8 2.8 7.7 1.8 6.7 1.2 7.9 21.9 9.4 12.0 1.0 7.6 13.7 10.5 1.4 5.5 10.7 3.7 38.8 7.9 5.4 12.1 12.4 5.1 1.7 5.0 5.0 14.8 3.6 2.1 13.4 1.9 4.9 8.3 1.8 5.2 8.5 2.3 322.9 8.9 10.8 6.2 2.2 3.0 5.4 32.2 7.3 2.2 4.7 96.9 0.9 8.4 8.8 5.3 0.9 1.0 14.1 5.4 5.8 1.9 1.3 1.0 0.5 0.9 1.3 0.3 0.6 0.7 4.0 3.3 2.0 1.4 1.3 0.5 0.8 1.3 4.2 7.7 0.7 1.2 0.8 0.1 2.7 3.3 1.7 1.2 0.6 2.8 24.8 4.1 0.7 0.7 2.3 0.5 1.3 1.0 6.3 0.2 1.7 9.0 3.1 0.3 0.5 0.4 7.1 9.3 1.3 0.6 1.2 3.5 1.6 1.3 11.8 2.3 3.3 3.5 0.6 5.9 1.2 6.1 0.6 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 6.7 21.9 9.4 7.9 5.4 5.0 5.0 4.9 2.2 7.3 5.3 12.9 0.0 2.8 3.9 1.0 1.7 0.8 0.3 0.6 5.7 1.9 3.0 19.1 1.5 0.8 0.0 20.9 0.2 0.6 0.1 0.0 0.3 0.6 0.4 2.8 10.2 0.0 0.8 6.7 0.4 0.6 4.4 0.5 0.4 0.0 9.9 6.8 5.3 0.4 6.7 13.7 0.3 0.0 2.5 0.7 3.1 5.6 0.5 1.8 4.7 0.4 1.9 1.0 5.5 1.5 0.4 0.0 2.6 1.9 0.5 3.3 2.9 0.3 7.5 0.0 12.0 2.9 3.3 1.2 0.5 1.0 0.1 0.8 0.5 0.8 0.5 SEMA6D "FLJ11598, KIAA1479" ENSG00000137872 "Semaphorin 6D" Q8NFY4 15 47184101-47774228 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.5;placenta: 43.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Horizontal cells: 79.1;Inhibitory neurons: 319.5;Oligodendrocytes: 140.1" "Cancer enriched" "Detected in many" 4 "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 14.9;SCLC-21H: 13.3;SH-SY5Y: 12.1;SuSa: 14.2;U-266/70: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043109 Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1100000 "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Golgi apparatus" "HPA043109: AB_10793941" "unprognostic (2.00e-1)" "unprognostic (4.62e-2)" "unprognostic (3.10e-2)" "unprognostic (3.83e-3)" "unprognostic (1.38e-1)" "unprognostic (3.85e-2)" "unprognostic (1.98e-1)" "unprognostic (2.17e-3)" "unprognostic (1.24e-1)" "unprognostic (5.36e-2)" "unprognostic (7.96e-4)" "unprognostic (1.42e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.74e-2)" "unprognostic (8.56e-2)" "unprognostic (3.30e-3)" "unprognostic (2.39e-4)" 5.5 1.5 11.3 3.9 27.9 0.4 5.0 11.1 21.3 5.8 0.0 10.6 21.8 1.6 2.5 1.7 4.9 4.0 9.4 9.8 16.3 15.1 3.1 8.9 2.1 17.2 31.1 26.7 16.1 10.6 5.5 43.1 23.1 4.5 12.7 15.8 4.5 8.4 20.9 3.0 38.5 3.3 12.0 2.5 3.0 2.6 20.5 2.7 5.8 6.0 0.6 3.1 10.0 28.8 0.0 0.0 2.5 0.0 1.5 1.2 0.2 0.6 14.9 0.4 0.0 0.3 0.1 2.2 0.0 4.0 0.0 7.6 3.4 1.1 0.1 1.1 1.7 0.0 5.0 0.0 4.0 0.0 0.2 1.1 8.3 0.0 0.5 0.0 1.0 5.7 0.1 3.4 0.4 0.8 2.8 0.7 4.6 0.0 0.0 1.6 0.1 2.4 1.1 1.1 13.3 12.1 0.1 1.0 4.3 14.2 0.5 0.0 0.0 6.9 0.3 0.2 0.0 10.0 0.0 2.3 1.8 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.3 27.9 11.1 21.3 9.8 16.3 17.2 31.1 23.1 12.0 20.5 28.8 13.9 51.3 1.5 72.8 0.2 2.0 4.0 1.4 1.2 6.2 0.5 10.7 10.0 4.3 2.1 11.0 114.7 19.7 0.1 40.6 5.9 1.0 0.2 0.5 2.3 10.1 17.4 0.0 120.7 0.2 1.8 10.8 0.0 0.3 3.8 71.0 5.0 0.9 2.6 79.1 319.5 5.4 0.0 0.0 1.9 1.2 23.3 1.0 8.8 15.9 0.0 9.3 0.0 43.2 140.1 0.3 8.5 13.5 0.0 1.2 53.5 0.2 0.1 2.3 0.0 9.3 13.9 0.8 6.3 0.3 1.1 4.7 0.2 3.4 15.1 1.6 SEMG1 "CT103, SEMG" ENSG00000124233 "Semenogelin 1" P04279 20 45207033-45209768 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 147 "seminal vesicle: 30405.5" "Group enriched" "Detected in some" 18 "Basal prostatic cells: 7.5;Prostatic glandular cells: 3.4" "Cancer enriched" "Detected in some" 14 "prostate cancer: 20.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 239 "eosinophil: 26.8" "Lineage enriched" "Detected in single" 269 "granulocytes: 26.8" "Cell line enhanced" "Detected in some" "NTERA-2: 1.3;THP-1: 3.1" "HPA042476, HPA064892" Enhanced "Secreted in male reproductive system" NA NA 7000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 43: THP-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" "HPA042476: AB_10794799, HPA064892: AB_2732724" "unprognostic (3.71e-1)" "unprognostic (2.92e-2)" "unprognostic (1.44e-1)" "unprognostic (3.32e-1)" "unprognostic (1.11e-2)" 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 207.1 0.0 0.0 0.0 30405.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 SEMG2 SGII ENSG00000124157 "Semenogelin 2" Q02383 20 45221373-45224458 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 149 "seminal vesicle: 10407.9" "Group enriched" "Detected in some" 9 "Basal prostatic cells: 1.2;Collecting duct cells: 3.7;Early spermatids: 1.2;Late spermatids: 1.8;Prostatic glandular cells: 1.9" "Cancer enriched" "Detected in single" 25 "prostate cancer: 9.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042767, HPA042835" Enhanced "Secreted in male reproductive system" NA NA 5000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 22: Epithelial cell types - Mixed function" "HPA042767: AB_10959312, HPA042835: AB_10964060" "unprognostic (1.39e-1)" "unprognostic (2.17e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.8 0.0 0.0 0.0 10407.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SENP7 ENSG00000138468 "SUMO specific peptidase 7" Q9BQF6 3 101324205-101513241 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 109.6;Oligodendrocyte precursor cells: 157.3;Oligodendrocytes: 134.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 44.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 44.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027259, HPA071998" Approved Supported "Nucleoplasm,Nuclear bodies,Centrosome,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Nuclear bodies, Centrosome, Cytosol" "HPA027259: AB_1856679, HPA071998: " "unprognostic (1.50e-1)" "unprognostic (6.12e-2)" "unprognostic (2.78e-2)" "unprognostic (7.31e-2)" "unprognostic (2.44e-2)" "prognostic favorable (4.23e-4)" "unprognostic (1.38e-3)" "unprognostic (9.25e-3)" "unprognostic (8.80e-2)" "unprognostic (2.24e-1)" "unprognostic (7.77e-3)" "unprognostic (1.94e-1)" "unprognostic (9.85e-2)" "unprognostic (8.08e-3)" "unprognostic (3.27e-1)" "unprognostic (9.03e-2)" "unprognostic (2.23e-2)" 15.1 9.7 9.7 13.7 12.7 24.7 16.9 21.8 11.8 15.8 9.7 12.5 7.3 26.8 14.7 7.8 16.1 14.2 9.5 9.3 12.3 11.4 8.7 12.8 23.1 13.9 11.7 26.3 12.8 16.9 10.2 19.4 14.0 12.7 10.8 26.0 8.9 11.5 11.2 20.8 12.4 14.7 10.1 16.9 14.1 9.1 11.5 20.5 17.5 11.2 17.7 11.8 11.4 20.3 9.2 6.1 29.4 16.4 5.6 8.2 5.3 5.2 3.8 8.5 10.4 4.0 8.3 7.0 7.9 5.1 7.8 9.1 9.4 4.8 17.0 13.0 2.7 12.7 5.1 5.5 4.5 7.4 12.2 6.4 8.5 4.3 9.6 7.6 12.2 13.4 10.5 17.6 8.1 6.1 13.7 8.6 6.0 4.8 6.3 15.2 8.0 6.4 10.1 5.2 11.3 8.8 4.8 4.8 6.5 15.0 8.0 9.8 10.2 11.8 7.1 3.9 5.2 12.2 7.8 16.4 4.1 9.7 9.8 44.1 5.9 5.9 5.8 5.4 7.3 6.4 7.8 5.8 4.8 9.0 10.3 7.1 17.3 9.3 6.3 4.1 6.9 6.1 9.7 12.7 21.8 11.8 9.3 12.3 13.9 11.7 14.0 10.1 11.5 20.3 44.5 16.0 24.9 78.4 33.0 9.1 8.4 7.4 21.1 48.3 14.4 12.2 21.6 2.8 18.4 16.5 20.9 5.8 30.8 5.4 5.9 8.1 4.1 33.1 48.5 28.4 13.1 18.7 62.4 5.2 2.7 23.4 21.4 34.1 37.2 28.6 32.9 10.3 8.2 52.2 109.6 6.5 12.2 20.5 9.5 4.0 18.3 19.1 10.6 80.6 13.6 16.7 35.0 157.3 134.4 6.9 4.1 19.5 23.5 4.8 7.0 8.5 27.5 33.8 46.0 29.7 23.3 22.8 19.9 13.4 9.9 2.5 41.0 21.1 5.9 6.1 SEPTIN9 "AF17q25, KIAA0991, MSF, MSF1, PNUTL4, SEPT9, SeptD1" ENSG00000184640 "Septin 9" Q9UHD8 17 77280569-77500596 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 29.9;Cytotrophoblasts: 78.2;dendritic cells: 34.8;Extravillous trophoblasts: 152.8;Hofbauer cells: 67.5;Syncytiotrophoblasts: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042564, HPA050627" Approved Enhanced "Actin filaments" No No 770000 "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA042564: AB_2678054, HPA050627: AB_2681193" "unprognostic (7.65e-2)" "unprognostic (5.44e-2)" "unprognostic (5.46e-3)" "unprognostic (2.34e-1)" "unprognostic (2.65e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (4.23e-3)" "unprognostic (1.56e-1)" "unprognostic (8.48e-2)" "unprognostic (1.99e-1)" "unprognostic (2.45e-1)" "unprognostic (1.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (1.33e-1)" "unprognostic (2.80e-1)" 68.7 87.9 58.8 148.8 61.7 89.2 72.8 81.6 85.3 99.3 59.9 137.8 94.9 127.5 27.0 81.9 89.0 88.3 70.5 68.1 68.6 75.2 99.5 77.8 223.8 111.5 62.0 76.4 38.7 67.2 63.3 80.7 76.6 96.0 51.9 15.6 76.8 75.6 73.1 80.3 145.1 84.5 68.2 152.8 103.1 60.0 65.7 260.2 52.9 43.1 151.5 122.9 82.4 71.8 246.1 342.0 221.3 186.4 257.0 417.1 121.7 188.9 214.1 122.4 89.0 278.4 243.4 338.7 153.4 388.5 161.2 149.1 96.6 354.8 90.4 6.2 65.0 128.8 147.3 483.2 212.0 84.6 218.3 215.6 128.8 159.6 136.0 180.3 167.5 196.4 144.6 44.1 110.7 258.1 628.1 72.0 207.5 281.4 281.1 290.7 192.6 117.1 197.5 337.9 171.0 324.3 214.2 349.6 207.2 248.6 260.2 60.7 243.6 165.8 147.6 197.4 130.2 10.5 19.5 562.6 245.6 73.7 348.7 4.2 18.4 31.1 22.3 46.3 19.0 16.3 28.7 26.4 17.0 17.4 29.6 25.8 6.1 16.9 55.3 38.7 31.8 24.9 58.8 61.7 81.6 85.3 68.1 68.6 111.5 62.0 76.6 68.2 65.7 71.8 29.9 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 78.2 34.8 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 152.8 9.4 0.0 0.0 0.0 0.0 0.0 0.0 67.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 70.6 6.8 0.0 0.0 0.0 SERPINA1 "A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1" ENSG00000197249 "Serpin family A member 1" P01009 14 94376747-94390693 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 45 "liver: 34022.4" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 42919.3" "Cancer enriched" "Detected in all" 10 "liver cancer: 3850.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 2482.1;intermediate monocyte: 3411.9;neutrophil: 2823.2;non-classical monocyte: 4518.8" "Group enriched" "Detected in all" 5 "granulocytes: 2823.2;monocytes: 4518.8" "Cell line enriched" "Detected in many" 10 "Hep G2: 4769.1" "Not detected" "Not detected" "Region enriched" "Detected in many" 6 "cerebellum: 130.6" "HPA000927, HPA001292, CAB013211, CAB016648, CAB073396" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 2070000000000 140000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB013211: , CAB016648: AB_1611888, CAB073396: , HPA000927: AB_1844761, HPA001292: AB_1844762" "prognostic favorable (1.61e-5)" "unprognostic (3.37e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.38e-2)" "unprognostic (1.98e-2)" "unprognostic (5.50e-3)" "unprognostic (3.81e-2)" "unprognostic (6.78e-2)" "unprognostic (2.54e-2)" "unprognostic (7.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.54e-1)" "unprognostic (1.23e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-2)" "unprognostic (1.17e-2)" "unprognostic (1.96e-1)" 49.1 9.7 7.3 225.0 7.1 157.1 100.6 9.1 21.3 105.7 11.1 151.0 278.6 42.3 5.3 10.1 22.4 352.3 12.5 7.3 11.1 621.2 34022.4 570.7 37.0 20.9 14.4 5.4 201.0 5.2 9.1 26.6 15.8 12.6 178.8 2.6 33.6 140.5 3.7 8.2 760.9 75.7 12.2 313.6 282.5 3.0 16.2 15.0 23.0 11.9 25.2 55.8 9.1 16.9 25.9 0.3 0.0 0.5 1.0 0.0 1.5 0.6 1.7 0.6 1.1 187.8 500.8 2.6 15.6 0.0 1.4 1.9 0.0 10.9 1.2 70.1 0.0 4.3 2.0 4769.1 0.3 16.8 2.3 4.1 5.4 0.3 18.5 1.9 0.0 0.0 3.2 0.4 0.0 0.8 1.1 12.1 2.0 5.5 8.0 1.9 16.7 2.4 300.8 3.0 0.6 1.3 6.4 1.6 1.4 0.4 262.1 2.7 1.6 2.1 59.4 1.9 7.1 3.3 1.8 7.0 4.4 41.8 0.6 10.6 2482.1 634.3 5.5 3411.9 6.8 7.7 3.6 4.1 683.6 3.6 4.3 3.6 2823.2 5.3 4518.8 14.9 4.5 2770.7 7.3 7.1 9.1 21.3 7.3 11.1 20.9 14.4 15.8 12.2 16.2 16.9 2.2 35.3 285.9 0.0 137.4 2.3 1.0 36.3 0.0 0.2 100.8 31.5 5.3 4520.9 165.5 150.8 0.0 1.6 3.9 52.0 68.4 3787.9 0.2 70.0 2.8 57.0 12.1 1227.4 0.0 225.8 4.5 3.6 36.2 51.3 1.3 0.1 938.8 42919.3 167.6 0.0 0.0 742.4 30.5 1454.0 74.1 1.1 0.0 413.3 1.8 1.0 291.7 0.3 9.2 0.0 0.0 2161.6 137.0 0.0 1.5 6.8 5270.0 745.9 108.3 0.2 0.0 0.6 17.4 0.0 0.2 0.6 1.7 6.4 75.5 0.0 83.2 6.7 SERPINA10 "PZI, ZPI" ENSG00000140093 "Serpin family A member 10" Q9UK55 14 94280460-94293268 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "liver: 346.9" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 259.1" "Cancer enriched" "Detected in some" 51 "liver cancer: 40.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 21.2" "Not detected" "Not detected" HPA048739 Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 3960000000 4700000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm Cytosol "HPA048739: AB_2797237" "unprognostic (7.14e-2)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.45e-1)" "prognostic favorable (9.00e-4)" "unprognostic (6.11e-2)" "unprognostic (2.81e-4)" "unprognostic (2.31e-4)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (7.93e-3)" 0.4 0.4 0.4 0.6 0.7 3.3 0.6 3.2 1.4 0.6 0.4 0.7 0.7 0.7 0.5 0.4 0.3 0.5 0.6 0.4 0.4 0.5 346.9 0.4 0.8 1.5 0.5 0.9 0.5 0.2 0.2 0.5 0.8 0.4 0.7 3.1 0.4 0.4 0.5 1.7 0.7 0.6 0.4 0.7 0.7 0.6 0.7 1.3 0.7 0.4 0.4 0.2 0.1 2.5 0.6 0.2 1.8 0.7 0.7 0.6 0.4 0.5 0.5 0.9 0.8 2.7 0.6 2.1 0.3 0.4 0.2 0.4 2.2 0.5 1.3 0.8 1.4 2.0 0.8 21.2 0.4 1.6 1.1 0.6 0.5 0.3 0.7 1.1 1.0 1.1 0.5 1.3 1.0 0.3 1.4 0.8 0.8 0.2 0.6 0.9 1.2 0.9 0.5 0.7 0.9 0.8 0.4 0.4 0.2 1.0 0.9 0.9 0.6 0.7 0.4 0.7 0.6 1.1 0.5 0.9 0.9 1.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 3.2 1.4 0.4 0.4 1.5 0.5 0.8 0.4 0.7 2.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.8 2.8 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 6.6 8.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 3.3 259.1 0.0 0.0 0.0 0.4 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SERPINA11 ENSG00000186910 "Serpin family A member 11" Q86U17 14 94442464-94452800 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 92 "liver: 490.6" "Cell type enriched" "Detected in some" 46 "Hepatocytes: 278.7" "Cancer enriched" "Detected in some" 9 "liver cancer: 94.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 17.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 230000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.50e-2)" "unprognostic (3.26e-1)" "unprognostic (9.00e-2)" "prognostic favorable (6.30e-4)" "unprognostic (7.44e-2)" "unprognostic (2.02e-2)" "unprognostic (1.70e-1)" "unprognostic (3.44e-1)" "unprognostic (5.14e-2)" "unprognostic (1.53e-1)" "unprognostic (1.64e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.1 5.3 0.0 0.0 0.0 0.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 490.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 3.9 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.3 0.0 0.0 4.3 1.8 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 278.7 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.2 SERPINA12 "OL-64, Vaspin" ENSG00000165953 "Serpin family A member 12" Q8IW75 14 94487274-94517844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 396.4" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 20.9" "Group enriched" "Detected in some" 5 "liver cancer: 1.8;melanoma: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "Hep G2: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 6500000 "Cluster 61: Skin - Cornification" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.82e-3)" "unprognostic (6.44e-2)" "unprognostic (3.25e-1)" "unprognostic (1.00e-2)" "unprognostic (5.98e-2)" "unprognostic (2.97e-2)" "unprognostic (7.64e-3)" "unprognostic (6.67e-2)" 0.3 0.0 0.0 0.0 0.0 0.1 27.7 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 396.4 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 SERPINA3 "AACT, ACT" ENSG00000196136 "Serpin family A member 3" P01011 14 94612384-94624055 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 9176.5;pancreas: 4910.2" "Cell type enhanced" "Detected in some" "Ductal cells: 20.9;Exocrine glandular cells: 33.0;Fibroblasts: 68.6;Late spermatids: 12.2;Pancreatic endocrine cells: 18.7" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "Hep G2: 449.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000893, HPA002560, CAB016647" Enhanced "Secreted to blood" NA NA 697000000000 94000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB016647: AB_1611882, HPA000893: AB_10794315, HPA002560: AB_1856717" "prognostic favorable (8.92e-4)" "unprognostic (3.33e-3)" "unprognostic (9.21e-2)" "unprognostic (1.53e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (2.00e-2)" "unprognostic (1.00e-2)" "unprognostic (2.23e-1)" "unprognostic (9.60e-2)" "unprognostic (1.20e-2)" "unprognostic (9.92e-2)" "unprognostic (3.74e-12)" "unprognostic (6.47e-2)" "unprognostic (1.33e-2)" "unprognostic (2.02e-2)" 91.8 58.0 100.4 43.4 116.5 2.1 371.0 117.7 293.8 368.8 110.3 79.5 11.7 44.9 11.5 42.5 116.6 146.0 311.7 103.6 320.0 215.5 9176.5 169.9 5.0 196.3 183.1 181.5 4910.2 1.0 271.2 14.6 138.3 580.5 13.3 131.5 1505.8 54.9 177.8 55.7 91.6 83.1 141.4 31.7 290.5 66.9 176.3 2.6 72.6 38.9 6.4 207.4 70.4 173.0 0.2 0.5 0.0 0.3 0.2 0.8 0.3 0.1 0.1 0.0 0.0 1.2 4.9 0.6 4.5 0.0 3.3 0.9 0.0 4.4 0.0 2.7 0.0 1.0 0.2 449.9 56.9 1.9 0.7 52.0 63.9 0.0 2.5 5.4 0.0 0.0 0.3 0.2 0.0 17.1 0.5 0.5 0.8 1.6 0.0 0.6 2.2 0.2 3.8 0.2 0.1 0.0 1.8 2.5 65.6 0.4 2.4 0.0 0.6 0.0 8.5 0.1 19.4 1.1 2.0 2.1 0.4 0.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 116.5 117.7 293.8 103.6 320.0 196.3 183.1 138.3 141.4 176.3 173.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.5 1.8 0.0 5.6 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 20.9 3.7 0.2 0.1 0.3 0.0 0.0 0.0 33.0 0.0 68.6 9.7 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.3 0.0 0.0 1.0 0.2 0.0 0.0 0.0 18.7 0.0 0.4 0.3 0.5 0.0 0.1 1.5 0.0 0.0 1.7 0.8 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 SERPINA4 "KAL, kallistatin, KLST, KST, PI4" ENSG00000100665 "Serpin family A member 4" P29622 14 94561442-94569913 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 550.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 245.9;Exocrine glandular cells: 93.8;Hepatocytes: 478.5;Pancreatic endocrine cells: 62.1" "Cancer enriched" "Detected in many" 4 "liver cancer: 94.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 28.4" "Not detected" "Not detected" "HPA003607, HPA068939" Approved Uncertain Vesicles "Secreted to blood" NA NA 14500000000 14000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA003607: AB_1079914, HPA068939: " "unprognostic (1.65e-3)" "unprognostic (4.13e-2)" "prognostic favorable (2.95e-4)" "unprognostic (2.09e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (4.03e-3)" "unprognostic (1.02e-2)" "unprognostic (2.24e-4)" "unprognostic (1.08e-1)" "unprognostic (5.45e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 2.8 0.4 41.0 0.0 1.5 53.4 0.0 0.0 0.0 7.3 550.0 0.0 0.0 0.0 0.0 0.0 116.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.5 0.0 0.0 0.3 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 245.9 0.0 3.7 0.0 0.0 0.0 0.0 11.7 30.0 0.0 3.3 0.3 0.3 0.0 2.7 0.0 93.8 0.0 0.0 5.1 4.5 0.0 0.2 5.3 478.5 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 62.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 SERPINA5 "PAI3, PCI, PLANH3, PROCI" ENSG00000188488 "Serpin family A member 5" P05154 14 94561442-94593118 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Fertilization, Lipid transport, Transport" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 484.5;liver: 785.6;testis: 432.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 400.4;Endometrial ciliated cells: 175.2;Glandular and luminal cells: 345.3;Hepatocytes: 198.2;Late spermatids: 277.8;Peritubular cells: 144.4" "Cancer enhanced" "Detected in many" "liver cancer: 121.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 261.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA078846 Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA078846: " "unprognostic (5.94e-3)" "unprognostic (2.64e-4)" "unprognostic (1.13e-1)" "prognostic favorable (7.72e-4)" "unprognostic (3.34e-3)" "unprognostic (6.10e-3)" "unprognostic (3.94e-2)" "unprognostic (1.39e-3)" "unprognostic (5.36e-1)" "unprognostic (1.50e-1)" "unprognostic (6.16e-2)" "unprognostic (1.87e-2)" "unprognostic (8.39e-3)" "unprognostic (3.38e-3)" "unprognostic (9.92e-2)" "unprognostic (8.08e-2)" "unprognostic (3.23e-1)" 5.1 484.5 1.8 3.3 2.4 0.0 19.6 2.2 1.7 29.6 3.0 5.3 5.5 31.8 1.2 0.8 26.3 160.5 19.0 1.6 7.2 151.4 785.6 1.0 3.6 3.5 3.8 30.1 173.9 0.2 3.2 0.1 5.3 6.8 1.9 14.0 9.4 153.3 46.4 3.3 3.6 2.1 1.7 112.2 12.1 432.4 2.8 0.9 4.1 152.6 4.7 2.3 4.0 3.7 0.8 0.1 2.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 12.0 12.2 0.0 8.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 261.3 0.3 0.4 0.0 1.7 0.3 0.1 0.0 2.3 4.9 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.0 0.1 0.5 0.2 3.9 0.1 0.4 17.4 0.2 0.1 7.9 0.9 0.1 0.0 0.5 0.0 0.6 0.4 1.5 0.2 0.1 0.2 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.4 2.2 1.7 1.6 7.2 3.5 3.8 5.3 1.7 2.8 3.7 0.9 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.2 18.9 14.1 0.8 400.4 0.1 33.1 2.1 0.0 0.1 0.0 64.6 103.2 78.7 175.2 19.7 40.3 0.0 2.7 0.0 122.2 0.0 18.2 0.5 345.3 0.0 78.2 2.5 198.2 0.0 8.4 0.0 0.0 0.0 3.2 0.7 277.8 57.2 1.9 0.0 0.0 0.6 5.4 0.0 0.0 0.2 18.3 0.0 144.4 0.0 0.1 0.0 7.5 0.0 1.4 6.6 11.6 1.5 11.1 2.9 0.0 0.6 0.3 1.8 58.7 0.0 0.1 SERPINA6 CBG ENSG00000170099 "Serpin family A member 6" P08185 14 94304248-94323389 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "liver: 776.6" "Group enriched" "Detected in some" 4 "Cholangiocytes: 204.5;Hepatocytes: 390.8" "Cancer enriched" "Detected in many" 9 "liver cancer: 244.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "T-47d: 961.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA017864 Approved "Secreted to blood" NA NA 60800000000 37000000000 "Cluster 62: Liver - Hemostasis" "Cluster 6: T47d - Mammary gland" "Cluster 15: Hepatocytes - Hemostasis" "HPA017864: AB_1856721" "unprognostic (2.82e-2)" "unprognostic (1.67e-1)" "unprognostic (1.02e-3)" "prognostic favorable (6.96e-5)" "unprognostic (2.93e-3)" "unprognostic (9.98e-3)" "unprognostic (4.43e-2)" "unprognostic (3.11e-1)" "unprognostic (4.80e-3)" "unprognostic (2.94e-1)" "unprognostic (2.47e-2)" "unprognostic (4.54e-2)" "unprognostic (1.43e-1)" "unprognostic (2.14e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 1.9 0.0 3.5 0.1 0.5 0.0 0.0 12.6 35.1 0.0 0.0 0.0 43.5 776.6 0.1 0.0 0.0 0.0 0.3 17.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 114.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.4 0.4 4.5 0.1 0.4 0.0 0.1 0.7 0.0 0.0 961.9 0.0 0.0 0.5 0.0 0.6 0.0 0.3 0.0 0.5 1.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.1 0.1 0.1 0.7 0.0 0.0 4.4 0.0 0.4 204.5 0.3 0.0 0.0 0.3 0.0 0.4 1.9 33.1 0.0 62.6 0.3 0.4 9.0 16.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.2 9.7 390.8 0.0 0.0 0.0 0.8 2.0 8.7 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.1 1.0 1.2 0.0 0.0 0.0 0.1 43.0 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.8 0.1 SERPINA7 TBG ENSG00000123561 "Serpin family A member 7" P05543 X 106032435-106038727 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 612 "liver: 282.2" "Cell type enriched" "Detected in some" 27 "Hepatocytes: 182.8" "Cancer enriched" "Detected in single" 203 "liver cancer: 82.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 475 "Hep G2: 69.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA002803 Approved "Secreted to blood" NA NA 39800000000 25000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA002803: AB_1079915" "unprognostic (6.22e-2)" "unprognostic (1.63e-3)" "unprognostic (3.34e-1)" "unprognostic (2.62e-1)" "unprognostic (2.15e-3)" "unprognostic (2.95e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 282.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 182.8 0.0 0.0 0.0 0.7 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 SERPINA9 "CENTERIN, GCET1, SERPINA11b" ENSG00000170054 "Serpin family A member 9" Q86WD7 14 94462717-94479689 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "lymphoid tissue: 72.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "stomach cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 66 "Daudi: 69.5" "Region enriched" "Detected in many" 16 "basal ganglia: 71.8" "Secreted to blood" NA NA "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (1.32e-2)" "unprognostic (1.05e-1)" "unprognostic (1.94e-2)" "unprognostic (3.89e-3)" "unprognostic (6.10e-2)" "unprognostic (6.67e-2)" "unprognostic (1.38e-2)" "unprognostic (1.16e-1)" 0.0 0.0 0.0 13.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 1.7 0.8 0.1 0.0 0.3 0.2 0.0 0.0 1.4 0.0 0.0 72.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 69.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SERPINB1 "anti-elastase, EI, ELANH2, PI2" ENSG00000021355 "Serpin family B member 1" P30740 6 2832332-2841959 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 466.8;esophagus: 478.3" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 1424.3;Pancreatic endocrine cells: 1067.8;Urothelial cells: 984.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.3;OE19: 162.5;U-937: 144.9" "Low region specificity" "Detected in all" "HPA018871, HPA018882, HPA052642" Enhanced Supported "Cytoplasmic bodies" "Secreted to blood" NA NA 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cytoplasmic bodies" "HPA018871: AB_1856724, HPA018882: , HPA052642: AB_2681896" "unprognostic (1.13e-2)" "unprognostic (1.93e-1)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (5.14e-3)" "unprognostic (9.67e-2)" "unprognostic (3.59e-3)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (1.88e-2)" "unprognostic (1.08e-3)" "unprognostic (9.07e-2)" "unprognostic (1.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" 36.6 54.4 10.7 69.7 14.4 466.8 25.0 11.1 14.0 55.6 17.3 77.7 140.4 15.6 22.2 478.3 35.8 57.4 26.8 10.7 12.7 33.2 32.1 81.7 51.3 15.1 13.0 18.1 232.1 29.8 32.9 27.0 14.6 15.9 87.5 13.4 99.6 16.9 54.2 15.8 107.3 24.9 13.6 67.4 97.9 7.1 13.7 31.9 30.7 22.9 122.8 88.6 112.4 14.8 42.9 49.7 2.7 0.3 10.6 21.8 41.2 11.8 36.1 14.5 26.1 47.1 125.3 0.3 86.6 26.6 15.6 26.8 4.8 11.4 11.1 59.4 7.5 76.6 16.0 37.0 37.2 13.5 46.2 26.8 18.4 7.3 3.3 7.2 48.7 0.0 27.1 9.9 13.4 19.9 1.7 35.4 4.5 162.5 22.1 3.9 0.5 44.4 51.0 9.3 8.8 4.8 28.8 11.2 64.2 5.9 5.6 43.2 29.1 4.6 10.4 10.2 3.6 0.1 2.2 0.5 17.4 144.9 2.4 118.0 207.1 109.4 53.3 103.7 45.8 43.5 48.1 48.4 150.4 32.3 47.4 50.6 182.3 85.1 82.8 48.6 58.5 175.8 10.7 14.4 11.1 14.0 10.7 12.7 15.1 13.0 14.6 13.6 13.7 14.8 79.9 240.4 269.9 0.7 90.7 35.1 165.1 699.1 38.1 4.2 55.0 51.2 17.6 72.9 420.9 46.0 2.1 124.5 120.8 264.1 56.7 490.3 1.7 210.6 28.7 118.9 96.3 176.3 0.9 1424.3 149.1 89.1 345.1 104.5 452.2 32.1 124.9 20.2 183.0 10.1 0.9 263.1 109.9 332.7 308.2 3.5 34.8 387.3 71.2 15.9 589.7 48.3 139.0 4.5 6.6 1067.8 308.4 27.8 65.2 147.5 333.7 81.3 343.8 17.2 13.1 109.7 67.2 2.0 11.2 461.5 38.1 99.7 112.9 59.2 242.6 984.3 SERPINB10 "bomapin, PI10" ENSG00000242550 "Serpin family B member 10" P48595 18 63897174-63936111 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 60 "bone marrow: 74.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.4;Club cells: 2.7;Erythroid cells: 1.3;Kupffer cells: 1.2;monocytes: 4.7;Respiratory ciliated cells: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;eosinophil: 1.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "U-937: 104.1" "Not detected" "Not detected" "HPA015480, HPA059582" Uncertain Supported Nucleoplasm,Cytosol NA NA 59000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA015480: AB_1855456, HPA059582: AB_2684072" "unprognostic (4.66e-1)" "unprognostic (5.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (9.56e-2)" "unprognostic (2.56e-1)" "unprognostic (4.59e-1)" "unprognostic (1.10e-1)" "unprognostic (3.64e-1)" "unprognostic (1.25e-4)" 0.3 0.1 0.1 0.1 0.2 74.7 0.0 0.5 0.4 0.3 0.1 0.0 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.1 1.2 0.1 0.1 0.1 0.7 0.1 0.0 0.3 0.9 0.0 0.0 0.6 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.1 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.0 14.5 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.7 0.1 1.5 0.1 0.0 0.0 0.1 0.1 104.1 0.1 0.1 1.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.3 0.1 0.2 0.5 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.4 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.7 0.0 0.0 4.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.2 SERPINB11 EPIPIN ENSG00000206072 "Serpin family B member 11" Q96P15 18 63647579-63726432 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 27.4;prostate: 32.5" "Cell type enhanced" "Detected in some" "Club cells: 6.8;Prostatic glandular cells: 3.3;Respiratory ciliated cells: 4.4;Squamous epithelial cells: 13.7;Urothelial cells: 21.9" "Cancer enriched" "Detected in some" 5 "prostate cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (5.04e-3)" "unprognostic (4.76e-2)" "unprognostic (4.05e-2)" "unprognostic (3.44e-1)" "unprognostic (2.62e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 32.5 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 9.0 2.9 6.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.2 0.0 0.0 21.9 SERPINB12 YUKOPIN ENSG00000166634 "Serpin family B member 12" Q96P63 18 63542369-63569329 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 13.9;skin 1: 59.1;vagina: 25.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "cervical cancer: 7.3;head and neck cancer: 2.1;lung cancer: 1.9;melanoma: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 8200000 "Cluster 31: Skin - Epidermis development" "unprognostic (7.35e-2)" "prognostic favorable (1.76e-4)" "unprognostic (1.57e-1)" "unprognostic (2.00e-1)" "unprognostic (8.10e-2)" 0.0 0.0 0.1 0.0 0.2 0.1 3.3 0.4 0.2 13.9 0.2 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.2 59.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 3.4 0.0 0.1 2.1 0.0 25.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 SERPINB13 "headpin, HUR7, hurpin, PI13" ENSG00000197641 "Serpin family B member 13" Q9UIV8 18 63586989-63604639 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 56.6;esophagus: 180.4;vagina: 135.0" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 58.8;Club cells: 54.8;Squamous epithelial cells: 148.6" "Group enriched" "Detected in many" 5 "cervical cancer: 45.9;head and neck cancer: 27.6;lung cancer: 12.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 129 "HaCaT: 198.9;hTCEpi: 74.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052630, HPA057129" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 210000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles, Cytosol" "HPA052630: AB_2681891, HPA057129: AB_2683347" "unprognostic (3.49e-2)" "unprognostic (3.73e-1)" "unprognostic (1.11e-1)" "unprognostic (7.27e-2)" "unprognostic (2.28e-1)" "unprognostic (4.29e-2)" "unprognostic (2.81e-1)" "unprognostic (6.04e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 56.6 0.0 0.0 0.0 0.0 0.0 180.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 35.7 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.0 22.9 3.3 135.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 1.7 1.9 58.8 13.1 0.0 0.0 0.1 0.1 0.0 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 0.0 8.5 0.0 0.0 0.0 1.0 0.0 0.0 148.6 1.3 0.5 0.0 0.0 0.0 19.9 SERPINB2 "HsT1201, PAI2, PLANH2" ENSG00000197632 "Serpin family B member 2" P05120 18 63871692-63903888 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Plasminogen activation" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 239.1;lymphoid tissue: 81.2;skin 1: 89.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2243.9;Suprabasal keratinocytes: 1053.6;Syncytiotrophoblasts: 439.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.5" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.3;thalamus: 1.1" "Immune cell enhanced" "Detected in some" "basophil: 22.0;eosinophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 22.0" "Cell line enhanced" "Detected in many" "GAMG: 282.7;HaCaT: 699.1;U-138 MG: 807.0;U-2197: 1243.9" "Region enriched" "Detected in single" 15 "cerebellum: 2.6" "Not detected" "Not detected" "HPA015480, HPA076596, HPA076608" Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "HPA015480: AB_1855456, HPA076596: , HPA076608: " "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.46e-2)" "unprognostic (1.36e-4)" "unprognostic (1.17e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (9.69e-2)" "unprognostic (3.76e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-6)" "unprognostic (3.89e-2)" "unprognostic (3.94e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.55e-5)" 21.0 0.3 0.0 8.6 0.0 36.5 8.7 0.0 1.3 21.0 0.0 0.5 0.1 0.7 0.0 239.1 8.4 0.7 1.0 0.0 0.2 0.2 0.3 2.8 0.0 0.0 0.1 0.3 1.1 0.2 0.1 50.1 0.0 0.2 0.0 0.0 31.2 0.0 0.3 89.2 0.1 1.7 0.0 0.3 0.8 0.0 1.1 2.6 0.1 0.2 81.2 6.6 45.4 0.0 1.4 0.0 0.0 0.8 1.3 0.6 0.2 169.2 179.2 6.0 13.1 0.9 0.4 0.2 0.0 6.1 282.7 699.1 0.0 143.7 118.6 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.5 1.5 13.9 81.7 37.0 1.8 0.6 0.0 0.6 0.4 2.8 0.0 0.2 0.4 0.3 0.2 1.8 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.6 1.1 0.0 0.6 0.7 15.7 13.9 807.0 0.4 1243.9 0.0 0.2 0.1 0.0 21.6 1.8 96.7 22.0 4.9 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.5 0.0 0.2 2243.9 4.1 82.1 0.0 0.0 0.6 0.1 0.7 0.0 153.4 0.0 0.0 6.2 0.1 0.0 0.0 92.6 0.0 0.1 0.1 5.5 0.0 0.0 0.0 7.1 1.7 11.0 0.0 0.3 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 26.4 2.9 86.4 0.0 0.0 73.1 94.3 0.0 3.9 0.0 0.0 0.0 0.0 167.2 0.0 0.0 1.0 18.9 0.0 0.0 94.5 0.0 0.0 0.3 14.8 0.0 0.0 94.7 1053.6 439.3 2.5 0.0 0.0 52.0 SERPINB3 "HsT1196, SCC, SCCA1, T4-A" ENSG00000057149 "Serpin family B member 3" P29508 18 63655197-63661893 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "cervix: 418.5;esophagus: 809.7;vagina: 669.6" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 6903.4;Club cells: 6726.1" "Group enriched" "Detected in many" 4 "cervical cancer: 186.5;head and neck cancer: 69.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.9;HaCaT: 6.5;HBEC3-KT: 1.6;SiHa: 4.1;U-2197: 8.2" "CAB018772, CAB036006, CAB036007, HPA048341, HPA049988, HPA055992" Enhanced Approved "Plasma membrane,Cytosol" NA NA 9100000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB018772: AB_2285759, CAB036006: , CAB036007: , HPA048341: AB_2680364, HPA049988: AB_2680985, HPA055992: AB_2682998" "unprognostic (2.95e-3)" "unprognostic (1.66e-1)" "unprognostic (2.03e-1)" "unprognostic (2.91e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (4.19e-3)" 0.1 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 418.5 0.0 0.1 0.0 3.2 0.0 809.7 0.2 0.2 0.4 0.0 0.0 0.1 0.2 3.1 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.0 0.0 7.6 0.0 0.0 100.0 0.0 0.1 42.9 0.1 0.0 0.0 0.1 0.5 1.9 0.0 4.8 0.1 0.0 19.6 73.8 669.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.1 6.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 35.2 6903.4 2.2 0.0 0.0 0.0 0.0 0.0 6726.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 31.4 0.1 0.2 0.5 0.0 0.0 0.0 8.9 0.0 3.0 0.0 0.9 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 986.7 0.0 0.0 55.4 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.4 0.0 60.2 0.0 0.2 447.6 0.0 0.0 0.0 178.1 1.0 0.3 413.5 0.0 0.3 0.8 0.0 0.0 265.9 SERPINB4 "LEUPIN, PI11, SCCA-2, SCCA1, SCCA2" ENSG00000206073 "Serpin family B member 4" P48594 18 63637259-63644256 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 78.6;esophagus: 93.3;vagina: 150.9" "Cell type enriched" "Detected in some" 4 "Basal respiratory cells: 3577.0" "Group enriched" "Detected in many" 5 "cervical cancer: 104.1;head and neck cancer: 29.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.2;HSkMC: 1.1;SiHa: 1.7;U-2197: 6.1" "HPA048341, HPA049988, HPA055992" Supported NA NA 10000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA048341: AB_2680364, HPA049988: AB_2680985, HPA055992: AB_2682998" "unprognostic (8.81e-3)" "unprognostic (9.43e-2)" "unprognostic (8.96e-3)" "unprognostic (4.38e-1)" "unprognostic (1.63e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (2.46e-1)" "unprognostic (4.37e-2)" "unprognostic (1.27e-2)" 0.1 0.0 0.0 2.7 0.0 0.0 0.1 0.0 0.0 78.6 0.0 0.0 0.0 0.6 0.0 93.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.3 0.0 0.0 23.3 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.4 0.0 0.0 4.5 21.0 150.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 3577.0 0.0 0.0 0.0 0.0 0.0 0.0 825.8 0.0 0.0 0.0 0.0 0.0 0.0 23.9 1.4 0.1 0.1 0.2 0.0 0.0 0.0 21.7 0.2 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 97.6 0.0 0.0 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 0.0 0.0 0.0 32.4 0.0 0.3 53.0 0.0 0.0 0.0 10.7 0.1 0.0 14.8 0.0 0.8 0.0 0.0 0.0 60.5 SERPINB5 "maspin, PI5" ENSG00000206075 "Serpin family B member 5" P36952 18 63476958-63505085 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 216.6;skin 1: 239.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 964.1;Basal prostatic cells: 358.7;Basal respiratory cells: 272.9;Squamous epithelial cells: 535.4;Suprabasal keratinocytes: 1215.3;Urothelial cells: 564.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 124.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1279.3;HBEC3-KT: 425.6;hTCEpi: 875.0;hTERT-HME1: 217.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB009570, HPA019025, HPA019132, HPA020136" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 770000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB009570: AB_2186315, HPA019025: AB_1856726, HPA019132: AB_1856727, HPA020136: AB_1856728" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (9.24e-2)" "unprognostic (1.04e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.36e-1)" "unprognostic (3.47e-3)" "prognostic unfavorable (5.71e-6)" "unprognostic (1.28e-1)" "unprognostic (1.84e-6)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (3.14e-1)" "unprognostic (8.38e-2)" 0.6 0.0 0.0 4.3 0.0 0.2 37.1 0.1 0.1 38.5 0.1 4.8 16.7 0.1 0.1 216.6 1.4 2.7 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 9.9 4.5 0.0 37.6 1.7 1.4 239.7 22.1 0.2 0.0 0.0 9.7 2.8 0.0 13.9 0.1 0.0 39.9 90.9 78.7 0.1 80.8 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 73.4 0.1 3.8 0.0 0.1 1279.3 0.0 425.6 0.0 0.0 0.0 0.0 95.8 0.2 0.0 0.0 0.6 0.1 875.0 0.0 217.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 179.9 93.4 0.1 0.0 0.2 0.0 95.1 1.4 0.0 60.2 0.3 0.0 0.3 0.2 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.2 0.9 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 964.1 358.7 272.9 224.3 0.0 5.1 27.3 0.2 0.0 90.0 3.7 0.0 0.3 0.1 14.2 0.0 0.1 9.0 6.2 0.1 5.4 3.5 0.0 0.3 0.0 0.2 5.8 12.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.3 34.6 0.0 57.6 18.6 0.6 1.8 62.2 0.0 0.0 0.0 0.0 0.0 0.1 16.3 51.7 0.0 2.5 85.4 13.5 0.1 85.4 0.0 0.0 0.0 7.1 6.6 2.2 535.4 1215.3 0.1 4.0 0.1 30.6 564.9 SERPINB6 "CAP, DFNB91, PI6, PTI" ENSG00000124570 "Serpin family B member 6" P35237 6 2948159-2972165 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 563.0;Late spermatids: 1154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA009668, HPA012736" Enhanced Approved Centrosome NA NA 4800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Centrosome "HPA009668: AB_1079919, HPA012736: AB_1856729" "unprognostic (3.44e-1)" "unprognostic (1.03e-1)" "unprognostic (8.72e-2)" "unprognostic (1.96e-3)" "unprognostic (2.72e-2)" "unprognostic (1.56e-2)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (7.63e-2)" "prognostic favorable (4.81e-4)" "unprognostic (3.51e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.59e-1)" "unprognostic (5.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.10e-2)" 122.7 170.7 101.1 66.9 108.4 66.6 107.9 103.6 134.3 135.9 103.8 133.7 191.2 95.9 82.2 131.5 118.9 77.7 243.9 98.6 104.2 136.7 63.3 151.7 52.7 111.7 107.1 169.7 282.5 94.4 92.0 133.5 110.6 160.4 103.3 56.4 92.5 95.6 232.0 50.9 210.3 89.4 105.8 164.5 115.0 203.8 106.7 26.7 101.3 266.8 47.2 107.7 95.5 115.4 156.2 99.6 32.2 134.3 85.6 189.2 99.2 142.1 170.7 109.9 127.3 35.0 108.5 0.8 161.6 161.7 124.8 228.8 90.3 144.1 102.2 204.9 41.2 90.7 111.8 60.0 148.5 1.1 53.0 109.4 98.5 104.8 26.9 191.1 263.7 0.5 118.7 2.0 198.0 110.7 0.5 1.5 19.1 175.5 188.8 10.1 59.3 130.7 138.7 37.1 1.5 82.5 116.9 17.3 162.4 118.6 75.3 73.8 188.7 111.1 41.4 252.0 97.1 3.0 0.6 2.7 85.4 90.8 117.8 60.6 104.9 121.2 51.5 107.6 25.7 27.3 28.9 35.5 103.6 22.9 33.7 56.1 8.6 86.0 90.7 10.3 5.0 91.1 101.1 108.4 103.6 134.3 98.6 104.2 111.7 107.1 110.6 105.8 106.7 115.4 127.8 51.3 69.6 34.3 33.0 20.5 68.4 141.8 23.9 28.4 62.4 63.0 142.6 42.9 141.6 75.4 20.9 146.4 56.8 237.9 99.7 194.6 563.0 89.4 91.4 137.5 73.0 29.9 14.2 338.3 346.6 84.9 108.6 47.8 104.5 83.5 232.7 31.9 182.3 30.3 21.5 169.7 114.0 181.9 70.2 1154.3 83.3 124.2 64.0 92.8 151.8 172.4 46.4 31.7 56.2 318.5 237.0 85.0 17.4 99.3 418.3 216.4 174.2 50.4 78.9 119.7 104.6 233.2 33.1 34.0 26.3 161.4 42.2 65.0 206.5 94.9 SERPINB7 MEGSIN ENSG00000166396 "Serpin family B member 7" O75635 18 63752935-63805376 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lymphoid tissue: 38.4;skin 1: 129.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 79.5;Basal respiratory cells: 353.3;Club cells: 120.7;Ductal cells: 157.8;Extravillous trophoblasts: 82.2;Pancreatic endocrine cells: 276.5" "Cancer enhanced" "Detected in many" "cervical cancer: 8.0;head and neck cancer: 8.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 240.4;fHDF/TERT166: 170.8;HaCaT: 412.8;HBEC3-KT: 131.9;HBF TERT88: 223.0;hTERT-HME1: 130.9;U-138 MG: 219.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "cerebral cortex: 12.9;hippocampal formation: 11.4" HPA024200 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 160000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" Mitochondria "HPA024200: AB_1856730" "unprognostic (8.66e-3)" "unprognostic (6.31e-3)" "unprognostic (6.55e-2)" "unprognostic (4.03e-4)" "unprognostic (9.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (9.99e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (2.02e-1)" "unprognostic (6.81e-2)" "unprognostic (1.62e-1)" "unprognostic (3.37e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-3)" 0.5 0.0 0.0 0.4 0.0 0.0 13.0 0.0 0.0 3.0 0.0 0.7 0.0 0.7 0.0 1.8 0.0 0.3 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.7 0.0 0.5 129.5 0.0 0.1 0.0 0.0 0.7 0.4 0.1 4.5 0.0 0.0 38.4 0.0 4.8 0.0 28.2 0.1 0.0 0.1 0.0 3.7 0.0 240.4 48.2 36.0 26.6 0.0 1.0 0.1 0.1 170.8 62.5 412.8 0.1 131.9 223.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 8.6 22.9 5.5 130.9 1.8 0.0 0.0 0.0 0.8 21.7 0.0 0.0 0.0 0.6 0.0 11.9 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.8 0.1 0.2 0.0 219.4 8.1 4.7 22.8 0.1 0.0 0.0 22.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 79.5 0.9 353.3 0.0 0.0 0.1 0.0 0.0 0.0 120.7 0.0 0.0 1.9 0.0 0.5 0.0 157.8 0.1 0.0 0.0 0.5 0.0 0.0 0.2 8.8 82.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 2.0 0.0 3.0 0.0 0.0 0.2 3.6 0.0 1.6 0.0 0.0 0.5 0.3 276.5 1.1 0.0 0.0 4.5 0.0 0.3 13.0 0.0 0.0 0.0 5.4 0.0 0.2 0.0 21.9 6.2 0.1 0.0 0.0 8.2 SERPINB8 "CAP2, PI8" ENSG00000166401 "Serpin family B member 8" P50452 18 63970029-64019779 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 58.8" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 120.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB034300 Enhanced Approved Nucleoplasm,Cytosol NA NA 920000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB034300: AB_2186486" "unprognostic (8.49e-2)" "unprognostic (4.87e-2)" "unprognostic (4.10e-3)" "unprognostic (2.86e-2)" "unprognostic (1.52e-2)" "unprognostic (7.71e-2)" "unprognostic (4.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.58e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (8.73e-2)" "unprognostic (3.48e-2)" "unprognostic (1.25e-1)" "unprognostic (1.90e-1)" 10.8 9.5 2.6 15.8 3.2 30.3 9.5 3.4 3.6 9.3 3.5 8.6 6.3 4.7 1.5 30.1 4.4 18.1 5.7 2.8 3.9 9.0 37.8 12.1 13.4 5.2 4.0 4.2 7.1 2.7 3.7 7.2 4.8 4.6 9.7 2.3 10.8 3.3 3.0 58.8 8.8 7.3 4.3 7.8 7.1 2.7 4.6 6.5 5.3 2.3 18.3 23.7 17.1 4.5 24.2 4.8 4.0 28.8 13.9 19.7 2.0 75.6 72.9 46.8 46.4 1.0 10.8 0.4 27.2 45.6 23.3 38.3 0.8 48.2 66.3 33.4 0.9 0.0 8.7 2.5 32.1 120.0 10.0 19.1 41.3 63.6 20.9 30.3 51.4 5.1 0.7 13.4 32.9 2.1 2.1 13.5 1.7 3.8 23.6 1.7 10.5 2.1 21.4 27.1 2.3 2.4 15.0 2.3 28.8 3.3 0.8 45.4 79.2 71.0 15.4 8.8 31.1 5.9 1.0 0.1 72.5 69.2 63.0 2.7 44.2 2.0 7.6 34.2 6.8 7.1 6.3 4.7 53.8 9.9 3.3 5.2 12.4 4.6 18.1 28.8 8.9 11.2 2.6 3.2 3.4 3.6 2.8 3.9 5.2 4.0 4.8 4.3 4.6 4.5 6.0 3.2 8.3 0.3 9.1 41.0 25.9 38.9 5.7 0.4 5.5 3.8 1.2 8.6 25.5 0.0 0.0 4.9 13.4 12.3 0.0 30.0 1.3 7.6 3.3 8.7 1.8 3.0 1.8 19.2 5.6 8.6 8.2 16.3 4.5 0.9 7.5 9.6 15.3 0.0 1.3 3.5 12.2 24.8 35.1 1.1 0.9 35.9 16.0 1.0 29.0 1.6 5.2 1.5 2.9 42.2 10.7 0.0 3.5 13.0 8.5 2.9 12.9 0.3 0.0 12.3 9.8 1.7 2.3 18.2 48.4 31.3 8.2 1.4 5.0 33.3 SERPINB9 "CAP3, PI9" ENSG00000170542 "Serpin family B member 9" P50453 6 2887270-2903309 "Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 41.1;placenta: 52.3" "Cell type enriched" "Detected in many" 5 "Langerhans cells: 1527.7" "Cancer enriched" "Detected in all" 5 "testis cancer: 46.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 225.3;SuSa: 227.6;U-698: 98.8" "Low region specificity" "Detected in all" HPA030067 Uncertain Approved Nucleoplasm,Cytosol NA NA 3400000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA030067: AB_2673295" "unprognostic (6.82e-3)" "unprognostic (8.59e-2)" "unprognostic (1.39e-1)" "unprognostic (1.25e-1)" "unprognostic (4.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.12e-2)" "unprognostic (9.48e-2)" "unprognostic (2.12e-2)" "unprognostic (3.83e-3)" "unprognostic (1.06e-1)" "unprognostic (9.85e-2)" "prognostic unfavorable (1.66e-6)" "unprognostic (9.90e-2)" "unprognostic (8.56e-2)" "unprognostic (1.27e-1)" "unprognostic (3.76e-2)" 11.6 11.0 6.4 35.4 6.7 18.9 5.3 7.5 7.9 7.8 5.9 5.3 4.4 4.4 3.1 9.2 8.3 11.3 9.1 6.3 8.0 5.2 16.3 26.4 40.9 8.8 7.8 3.0 2.4 6.7 8.8 52.3 8.7 5.2 6.5 4.7 4.3 2.8 2.4 2.7 10.8 5.9 8.4 28.2 5.0 8.7 7.2 13.8 7.6 1.8 41.1 17.0 7.4 8.2 0.2 9.8 0.3 0.1 0.7 0.3 225.3 1.9 0.5 2.3 3.4 2.9 18.8 38.2 22.8 2.1 0.1 0.1 27.6 0.0 2.0 12.4 2.7 3.8 3.3 5.5 12.9 0.0 0.1 10.1 0.1 4.1 0.0 0.2 50.2 3.4 17.8 0.3 1.9 0.9 0.0 0.3 31.7 0.1 0.1 3.7 0.1 0.4 1.6 0.1 1.5 0.5 22.7 0.1 0.0 227.6 0.1 0.6 52.5 0.0 0.4 0.1 0.1 0.2 49.5 98.8 0.0 0.1 0.1 4.7 48.6 0.3 43.6 100.8 36.3 22.4 31.3 41.7 16.1 24.9 28.7 41.4 7.6 51.3 62.7 17.0 35.7 37.9 6.4 6.7 7.5 7.9 6.3 8.0 8.8 7.8 8.7 8.4 7.2 8.2 26.2 19.2 17.6 12.1 105.1 35.3 2.2 4.2 1.8 1.5 13.8 6.7 5.3 1.5 12.1 5.5 0.0 83.1 100.8 4.7 0.0 15.8 1.0 68.0 10.8 44.1 15.5 11.6 21.4 0.2 143.7 35.6 3.6 82.2 46.3 2.2 66.4 7.1 17.9 8.4 23.1 2.7 2.0 59.6 1527.7 4.9 4.4 232.6 88.9 92.8 99.8 5.3 43.3 1.0 3.2 9.3 6.0 17.7 115.7 2.5 0.1 2.4 10.4 3.0 13.1 55.3 14.6 0.4 2.2 3.8 36.9 270.2 100.6 8.1 3.4 6.9 SERPINC1 "AT3, ATIII, MGC22579" ENSG00000117601 "Serpin family C member 1" P01008 1 173903800-173917327 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1341 "liver: 5056.6" "Cell type enriched" "Detected in some" 49 "Hepatocytes: 2707.9" "Cancer enriched" "Detected in some" 871 "liver cancer: 1504.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 37 "Hep G2: 84.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001816, CAB016790, HPA024007" Supported "Secreted to blood" NA NA 120000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB016790: , HPA001816: AB_1079926, HPA024007: AB_1856732" "unprognostic (1.28e-2)" "unprognostic (2.22e-1)" "unprognostic (3.83e-2)" "unprognostic (5.98e-2)" "unprognostic (6.91e-2)" "unprognostic (1.93e-2)" "prognostic favorable (3.40e-5)" "unprognostic (1.75e-2)" "unprognostic (8.67e-2)" "unprognostic (3.48e-2)" "unprognostic (4.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.36e-2)" "unprognostic (5.28e-3)" "unprognostic (5.80e-2)" "unprognostic (6.35e-2)" "unprognostic (8.21e-2)" 0.3 0.1 0.2 0.0 0.3 0.0 0.1 0.3 0.3 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.3 0.2 3.7 5056.6 0.3 0.1 0.3 0.2 0.1 0.2 0.0 0.2 0.1 0.3 0.1 0.0 0.7 0.1 0.0 0.3 0.1 0.2 0.0 0.2 1.5 0.2 0.4 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 84.2 0.0 1.6 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.2 1.8 0.1 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.0 1.0 0.1 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.2 0.3 0.1 3.2 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 37.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.0 1.6 0.0 34.7 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.1 42.1 2707.9 0.2 0.0 0.1 0.0 0.0 55.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 4.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.3 3.7 0.0 0.0 0.2 SERPIND1 "D22S673, HC-II, HC2, HCF2, HLS2" ENSG00000099937 "Serpin family D member 1" P05546 22 20774113-20787720 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Chemotaxis, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 1253.1" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 283.7" "Cancer enriched" "Detected in many" 80 "liver cancer: 334.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "Hep G2: 208.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB008639, HPA055767" Supported Approved Vesicles "Secreted to blood" NA NA 50000000000 "Cluster 24: B-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB008639: AB_1618010, HPA055767: AB_2682912" "unprognostic (1.68e-1)" "unprognostic (8.27e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.09e-4)" "unprognostic (5.42e-2)" "unprognostic (1.23e-1)" "unprognostic (1.12e-3)" "unprognostic (1.56e-1)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (2.88e-1)" "unprognostic (3.94e-9)" "unprognostic (2.01e-1)" "unprognostic (4.66e-2)" "unprognostic (8.36e-3)" "unprognostic (1.46e-1)" 0.3 0.2 0.1 0.0 0.8 0.2 0.4 1.7 0.8 1.0 87.7 0.0 0.0 2.0 0.0 0.1 0.9 0.4 1.1 1.7 0.0 0.3 1253.1 2.5 0.0 0.0 0.0 1.8 0.5 10.1 0.8 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.2 0.0 0.2 0.4 0.1 0.2 0.0 0.7 0.0 0.0 0.8 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 208.2 0.1 0.8 0.5 0.1 0.0 1.6 0.0 0.0 20.4 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 2.4 16.5 0.0 0.7 0.0 0.0 3.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.1 0.0 0.1 0.1 0.0 0.2 7.2 0.2 13.9 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.1 0.3 0.0 0.5 0.1 0.0 0.1 0.8 1.7 0.8 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 11.3 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 2.7 1.6 0.0 0.1 2.3 0.0 0.0 1.3 0.0 3.9 283.7 0.1 0.0 0.9 0.0 0.0 6.3 0.0 0.0 1.2 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.5 3.4 0.0 0.0 SERPINE1 "PAI, PAI1, PLANH1" ENSG00000106366 "Serpin family E member 1" P05121 7 101127104-101139247 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 418.0" "Cell type enhanced" "Detected in many" "Endothelial cells: 165.1;Fibroblasts: 162.1;Pancreatic endocrine cells: 231.8;Smooth muscle cells: 239.3;Syncytiotrophoblasts: 651.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "NK-cell: 9.5" "Lineage enriched" "Detected in single" 20 "NK-cells: 9.5" "Cell line enhanced" "Detected in many" "BJ: 3483.8;HUVEC TERT2: 4014.7;LHCN-M2: 3874.5;TIME: 10032.6;U-138 MG: 4609.6;U-251 MG: 4256.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA050039, CAB068501" Uncertain Approved Cytosol "Secreted to blood" No No 142000000 13000000 "Cluster 22: NK-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB068501: AB_1642775, HPA050039: AB_2680997" "unprognostic (5.02e-2)" "prognostic unfavorable (5.01e-4)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.10e-2)" "unprognostic (9.04e-3)" "prognostic unfavorable (2.84e-5)" "unprognostic (6.80e-3)" "prognostic unfavorable (4.41e-6)" "unprognostic (2.33e-1)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.88e-8)" "prognostic unfavorable (3.27e-6)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (5.51e-4)" 215.5 75.3 3.1 91.6 3.4 1.7 56.2 5.2 12.8 62.1 5.0 31.7 7.4 31.1 1.0 16.4 41.3 360.3 136.0 3.9 6.6 166.2 345.8 260.2 21.3 6.4 3.7 105.6 135.1 11.8 12.3 418.0 4.5 37.8 5.4 4.9 10.6 8.0 17.8 21.2 13.1 74.3 4.8 13.8 30.3 5.5 12.7 6.7 59.5 4.3 3.5 359.9 19.2 6.0 77.3 64.4 1.2 5.1 766.6 1511.0 89.3 3483.8 654.6 1717.6 1487.4 9.4 5.5 2.7 812.6 1117.9 2367.3 18.1 0.4 269.4 1756.2 4.3 0.7 1.1 5.2 61.4 1532.6 0.2 3.8 596.1 106.9 2641.4 1374.8 928.5 4014.7 0.2 6.4 2.5 3874.5 0.4 0.6 2.2 18.2 1.3 41.7 0.6 6.1 4.8 5.1 30.3 1.0 0.8 286.3 77.2 8.3 410.9 3.3 9.9 10032.6 4609.6 204.0 1593.8 4256.0 0.6 2.9 4.2 1150.5 2.4 45.9 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 9.5 0.0 0.3 0.0 0.8 3.1 3.4 5.2 12.8 3.9 6.6 6.4 3.7 4.5 4.8 12.7 6.0 35.8 0.0 7.7 0.0 1.1 40.0 43.7 97.4 14.2 0.3 0.3 2.3 2.5 4.3 11.0 5.5 0.0 56.0 1.0 0.4 0.0 65.1 0.0 4.7 53.8 165.1 5.3 0.0 0.5 4.5 75.1 162.1 0.5 3.2 10.2 12.4 40.4 112.3 15.9 0.0 0.3 0.2 8.2 4.6 9.6 1.1 17.7 11.1 7.2 5.6 1.1 0.7 0.0 0.0 0.0 231.8 0.0 12.0 3.6 9.7 0.1 0.0 8.2 0.3 39.5 55.4 239.3 0.0 0.1 9.0 24.7 651.7 2.3 2.1 0.5 8.1 SERPINE2 "GDN, nexin, PI7, PN1, PNI" ENSG00000135919 "Serpin family E member 2" P07093 2 223975045-224039318 "Plasma proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein, Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 1091.9" "Cell type enriched" "Detected in many" 8 "Granulosa cells: 4466.0" "Cancer enriched" "Detected in all" 9 "melanoma: 271.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 12.9;naive CD8 T-cell: 6.8;NK-cell: 23.2" "Group enriched" "Detected in many" 15 "NK-cells: 23.2;T-cells: 12.9" "Cell line enhanced" "Detected in many" "BJ: 1492.9;fHDF/TERT166: 6425.1;SK-MEL-30: 2966.9;WM-115: 2183.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000277 Approved "Golgi apparatus" "Secreted in female reproductive system" NA NA 910000 "Cluster 48: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "HPA000277: " "unprognostic (1.73e-1)" "unprognostic (7.08e-3)" "unprognostic (8.49e-2)" "unprognostic (7.78e-3)" "unprognostic (2.57e-3)" "unprognostic (5.57e-2)" "unprognostic (1.49e-2)" "unprognostic (7.43e-3)" "unprognostic (4.41e-1)" "unprognostic (7.12e-2)" "unprognostic (7.56e-3)" "unprognostic (2.40e-1)" "unprognostic (1.97e-3)" "unprognostic (1.23e-2)" "unprognostic (1.31e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.48e-5)" 28.0 19.8 120.3 75.7 125.9 6.5 14.3 128.6 158.7 28.1 71.1 22.7 28.2 17.4 5.6 36.2 20.8 46.0 100.0 115.9 145.9 39.3 10.8 14.5 30.9 158.1 152.6 145.6 8.5 3.4 8.7 1091.9 134.4 26.4 21.8 5.4 12.6 7.5 6.6 11.2 27.0 119.6 141.1 30.9 8.9 57.6 146.4 17.0 26.1 10.8 44.0 146.9 27.6 132.0 3.1 83.8 29.4 32.6 1172.5 438.7 4.4 1492.9 851.5 118.1 112.7 4.8 7.0 0.4 32.5 6425.1 188.0 5.0 3.5 102.5 101.0 0.6 26.8 16.6 49.9 22.7 57.7 12.8 1.5 128.3 68.5 342.0 505.6 304.6 9.0 5.4 0.5 1.9 412.1 4.5 2.3 3.9 56.2 31.8 92.3 10.3 25.2 64.5 1100.2 97.5 43.0 7.1 284.4 0.5 2966.9 385.2 1.2 6.4 1056.5 692.5 96.6 214.4 72.7 6.3 13.3 0.8 443.5 11.1 2183.6 0.0 0.0 0.0 0.7 0.0 0.5 0.8 0.6 0.6 0.0 1.2 12.9 6.8 0.5 23.2 0.0 0.2 0.7 2.7 120.3 125.9 128.6 158.7 115.9 145.9 158.1 152.6 134.4 141.1 146.4 132.0 13.5 0.0 1.1 233.1 3.1 23.3 16.0 132.2 351.7 5.3 7.9 8.5 5.3 0.0 4.6 7.3 0.0 106.1 11.3 19.5 11.7 13.0 2.6 5.3 17.7 20.9 24.0 23.1 86.1 33.2 524.3 556.7 5.6 5.9 2.5 4466.0 23.2 0.0 45.5 0.0 11.4 4.7 0.0 0.8 26.9 9.9 401.4 9.7 142.3 23.4 3.5 2.5 2.1 199.6 13.5 22.1 14.9 98.9 5.6 27.2 2.0 146.2 1.7 3.5 13.1 5.2 146.6 4.2 70.9 34.8 14.5 133.9 10.7 18.9 3.1 7.2 SERPINE3 ENSG00000253309 "Serpin family E member 3" A8MV23 13 51335773-51364735 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;pancreas: 1.3;retina: 1.8" "Cell type enhanced" "Detected in some" "Astrocytes: 1.6;Early spermatids: 2.6;Excitatory neurons: 2.3;Inhibitory neurons: 1.9;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 2.5;Spermatocytes: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HeLa: 1.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 1.3" "HPA051904, HPA055804" Uncertain "Secreted in other tissues" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA051904: AB_2681659, HPA055804: AB_2682928" "unprognostic (1.60e-1)" "unprognostic (6.17e-2)" "unprognostic (9.66e-2)" "unprognostic (3.89e-2)" "unprognostic (5.52e-2)" "unprognostic (8.54e-3)" "unprognostic (2.67e-3)" "unprognostic (2.73e-1)" "unprognostic (1.87e-2)" "unprognostic (1.99e-3)" "unprognostic (1.70e-2)" "unprognostic (1.07e-1)" "unprognostic (3.94e-6)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (1.24e-1)" "unprognostic (3.31e-2)" 0.7 0.1 0.3 0.2 0.6 0.0 0.1 1.7 0.9 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.3 0.7 0.2 0.1 0.2 0.0 0.3 0.5 0.3 0.1 1.3 0.0 0.1 0.0 0.6 0.1 0.0 1.8 0.1 0.0 0.0 0.8 0.7 0.0 0.2 0.1 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 1.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.5 0.0 0.0 0.0 0.3 0.6 0.8 0.2 0.5 0.0 0.3 0.1 0.2 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 1.7 0.9 0.7 0.2 0.5 0.3 0.6 0.2 0.3 0.8 0.2 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.6 0.2 0.2 0.1 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.1 2.9 0.0 0.9 0.0 0.0 0.5 0.7 0.0 0.0 SERPINF1 "EPC-1, PEDF, PIG35" ENSG00000132386 "Serpin family F member 1" P36955 17 1762029-1777565 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1875.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 697.8;Cytotrophoblasts: 795.6;Fibroblasts: 951.9;Hepatocytes: 765.0;Leydig cells: 1818.0;Peritubular cells: 1045.7" "Cancer enhanced" "Detected in all" "liver cancer: 245.2" "Region enhanced" "Detected in many" "hippocampal formation: 85.4" "Immune cell enriched" "Detected in many" 18 "plasmacytoid DC: 1454.4" "Lineage enriched" "Detected in all" 121 "dendritic cells: 1454.4" "Group enriched" "Detected in many" 4 "ASC diff: 1232.0;ASC TERT1: 956.3;Hep G2: 606.0;HHSteC: 410.6;HSkMC: 1313.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005825 Uncertain "Secreted to blood" NA NA 9290000000 44000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA005825: AB_1079921" "unprognostic (3.85e-1)" "prognostic favorable (5.49e-4)" "unprognostic (9.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.32e-3)" "unprognostic (2.33e-1)" "unprognostic (7.88e-2)" "unprognostic (5.92e-2)" "unprognostic (1.69e-1)" "unprognostic (4.18e-2)" "prognostic unfavorable (1.40e-8)" "unprognostic (2.11e-3)" "unprognostic (2.82e-1)" "unprognostic (4.53e-3)" "unprognostic (1.25e-3)" 535.5 57.5 5.7 124.2 9.6 11.9 490.2 17.9 28.0 558.7 1875.2 131.3 41.9 358.2 90.2 109.3 557.4 559.7 376.5 85.4 1.1 35.1 974.8 158.9 133.5 0.1 5.1 408.3 207.6 11.2 62.4 311.6 1.3 202.8 52.0 61.4 124.6 105.8 434.8 162.9 131.7 221.7 2.8 133.2 124.7 277.7 25.4 106.2 193.1 465.5 117.7 323.4 273.5 7.0 0.5 3.7 2.8 2.0 1232.0 956.3 20.4 56.8 49.8 0.6 0.0 9.7 0.5 2.3 1.9 71.8 0.3 3.2 86.0 4.4 0.0 0.6 46.0 1.0 1.2 606.0 410.6 1.1 1.1 1313.4 6.9 0.9 1.1 11.4 0.6 4.2 117.5 0.4 63.2 0.2 7.0 7.2 30.7 0.3 1.0 2.9 219.9 1.6 0.1 6.0 1.9 42.2 0.7 0.7 57.0 3.4 6.7 184.2 2.0 0.5 17.6 14.1 1.2 0.7 2.4 28.1 1.7 0.6 0.8 0.1 12.0 1.1 0.6 4.4 0.4 9.0 0.7 0.9 79.8 5.2 2.0 5.5 1.7 1.3 0.2 1454.4 0.8 14.2 5.7 9.6 17.9 28.0 85.4 1.1 0.1 5.1 1.3 2.8 25.4 7.0 59.0 3.2 10.4 0.3 10.8 95.0 238.0 697.8 27.9 59.3 6.7 71.2 12.1 11.5 167.7 1.8 223.1 795.6 226.1 0.0 0.0 0.3 11.2 12.5 372.4 26.2 0.0 19.2 5.3 24.5 98.7 951.9 11.2 6.7 22.9 1.7 28.2 765.0 151.6 3.3 2.6 0.0 366.2 60.4 262.6 53.0 1818.0 79.0 108.5 9.4 79.0 11.6 1.0 0.5 2.0 6.8 0.1 1045.7 7.0 155.5 0.2 27.3 105.5 39.1 19.7 193.3 202.8 12.7 8.7 4.5 78.6 534.8 14.3 10.2 0.3 47.7 SERPINF2 "A2AP, AAP, ALPHA-2-PI, API, PLI" ENSG00000167711 "Serpin family F member 2" P08697 17 1742836-1755265 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 1578.5" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1007.7" "Cancer enriched" "Detected in all" 6 "liver cancer: 450.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 44.7" "Lineage enriched" "Detected in many" 23 "dendritic cells: 44.7" "Cell line enriched" "Detected in some" 24 "Hep G2: 145.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001885, CAB024863" Approved "Secreted to blood" NA NA 11900 61000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB024863: , HPA001885: AB_1079922" "unprognostic (2.17e-3)" "unprognostic (2.56e-3)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (3.69e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.18e-1)" "unprognostic (1.09e-3)" "unprognostic (7.05e-2)" "unprognostic (2.81e-1)" "unprognostic (7.68e-3)" "unprognostic (2.93e-1)" 11.6 2.0 1.4 4.3 1.5 0.4 18.3 1.2 2.2 7.1 11.1 4.2 0.7 8.7 101.4 3.0 19.6 0.7 2.5 2.0 1.4 74.1 1578.5 12.9 3.0 1.6 1.6 7.7 9.2 0.1 1.9 0.8 1.7 21.4 0.5 0.5 6.1 32.6 4.3 5.5 11.6 1.8 1.3 7.1 3.7 12.5 1.8 2.6 7.9 0.4 3.5 7.3 5.8 2.2 1.8 6.1 0.0 0.0 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 3.8 0.3 0.9 0.0 0.3 0.9 0.0 3.3 0.0 0.0 0.0 0.1 0.9 145.9 1.1 0.8 0.1 1.6 1.2 0.0 0.7 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.7 0.1 0.3 0.3 0.1 0.9 1.3 0.0 0.3 0.0 0.2 0.6 0.0 1.1 0.0 0.2 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.9 1.4 0.0 0.8 0.0 0.5 0.0 0.0 10.7 0.5 0.0 0.0 0.0 1.2 0.0 44.7 0.0 1.2 1.4 1.5 1.2 2.2 2.0 1.4 1.6 1.6 1.7 1.3 1.8 2.2 1.6 3.2 19.6 0.3 5.3 1.5 4.9 10.3 8.0 0.2 20.5 8.8 0.7 27.1 7.0 1.8 6.2 0.2 32.1 0.7 9.8 0.0 0.6 0.1 2.7 3.4 4.2 23.6 1.6 4.9 0.3 2.7 0.0 0.3 1.3 0.3 14.6 1007.7 7.7 0.0 1.9 2.1 12.2 32.2 20.1 0.8 33.8 8.2 1.8 1.0 10.9 0.1 0.0 1.0 0.7 3.8 2.7 26.7 3.2 2.8 2.2 87.5 4.4 0.4 0.0 1.3 1.2 0.4 0.5 1.3 1.6 0.3 2.6 0.0 3.3 1.8 SERPING1 "C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2" ENSG00000149131 "Serpin family G member 1" P05155 11 57597387-57619171 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Complement pathway, Fibrinolysis, Hemostasis, Immunity, Innate immunity" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2622.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 726.4;Ductal cells: 604.0;Fibroblasts: 793.6;Hepatocytes: 2530.0;Leydig cells: 735.3" "Cancer enhanced" "Detected in all" "liver cancer: 609.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 65.2;plasmacytoid DC: 60.6" "Group enriched" "Detected in many" 243 "dendritic cells: 60.6;granulocytes: 65.2;monocytes: 25.7" "Group enriched" "Detected in many" 6 "ASC diff: 1372.2;ASC TERT1: 694.9;HSkMC: 1159.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 194.1" "CAB026161, HPA048738" Supported "Secreted to blood" NA NA 28000000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "CAB026161: , HPA048738: AB_2680505" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (4.26e-2)" "unprognostic (4.38e-2)" "unprognostic (2.32e-1)" "unprognostic (4.12e-3)" "unprognostic (2.13e-1)" "unprognostic (8.95e-2)" "prognostic favorable (8.03e-4)" "unprognostic (5.92e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.60e-2)" "unprognostic (4.14e-2)" "unprognostic (2.56e-1)" "unprognostic (1.17e-1)" 971.5 144.2 27.4 90.0 27.5 10.9 733.0 27.1 36.0 629.4 53.4 358.7 52.0 616.7 163.3 162.0 793.2 533.0 547.1 26.2 34.8 337.3 2622.4 785.0 147.6 67.4 34.7 918.3 267.5 55.2 138.2 198.9 34.2 329.3 97.0 34.5 250.5 258.1 151.8 293.5 283.5 226.8 42.3 240.7 344.8 50.6 37.2 36.1 338.2 173.4 64.4 555.9 519.8 35.1 0.0 0.0 48.2 0.0 1372.2 694.9 7.3 74.2 57.0 16.8 30.7 2.5 0.0 0.0 96.7 42.1 0.0 0.0 0.4 4.7 9.4 0.0 0.1 33.7 0.0 1.7 170.3 0.9 5.4 1159.0 15.5 5.7 0.2 6.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 1.3 46.6 0.0 0.0 4.3 4.0 0.7 7.4 0.0 0.2 14.4 0.3 0.0 0.9 41.8 0.2 3.3 0.0 0.8 21.2 0.7 0.0 0.2 0.4 0.6 0.2 0.5 0.0 0.0 18.3 0.3 0.0 25.7 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 65.2 0.2 11.5 60.6 0.0 5.7 27.4 27.5 27.1 36.0 26.2 34.8 67.4 34.7 34.2 42.3 37.2 35.1 162.1 118.6 110.8 5.5 8.0 75.8 61.2 7.1 24.5 0.8 24.2 57.7 28.7 726.4 57.5 158.2 0.0 37.1 15.3 0.0 43.0 604.0 4.8 76.0 297.4 150.5 0.0 69.2 3.6 44.0 93.4 793.6 8.6 69.6 7.6 8.3 260.5 2530.0 43.6 0.0 6.2 0.1 2.0 118.9 94.2 25.6 735.3 46.9 90.7 15.9 10.4 57.2 0.0 3.5 0.5 41.4 0.0 228.7 4.5 32.4 0.0 53.5 23.1 4.5 269.5 143.6 259.6 2.5 10.4 9.0 59.5 25.2 16.8 3.4 0.0 37.4 SERPINH1 "CBP1, CBP2, colligen, HSP47, SERPINH2" ENSG00000149257 "Serpin family H member 1" P50454 11 75562056-75572783 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 473.6;Endometrial stromal cells: 273.3;Extravillous trophoblasts: 342.1;Fibroblasts: 287.6;Smooth muscle cells: 295.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 291.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 1018.3;fHDF/TERT166: 1215.2;HHSteC: 1029.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004441, HPA029198" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA Yes 920000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004441: AB_627757, HPA029198: AB_10601712" "unprognostic (3.80e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (5.93e-2)" "unprognostic (2.81e-3)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.39e-2)" "unprognostic (1.72e-3)" "unprognostic (2.35e-2)" "unprognostic (7.40e-2)" "unprognostic (1.57e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.22e-15)" "unprognostic (2.75e-2)" "unprognostic (1.27e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" 214.1 101.9 46.2 106.5 50.4 3.7 107.1 51.1 291.0 137.7 66.7 95.2 23.2 160.7 27.6 41.7 119.4 72.1 159.3 46.1 50.5 116.9 52.5 199.3 21.1 59.9 47.3 157.4 40.1 18.1 50.8 251.3 58.3 66.1 36.7 2.0 40.7 53.2 22.2 47.6 51.3 207.3 51.6 53.9 76.9 27.7 54.0 21.6 91.2 33.2 18.2 156.8 85.9 60.1 57.7 192.9 349.5 722.0 528.8 484.2 162.2 514.3 349.6 380.4 483.5 1018.3 294.1 0.4 470.2 1215.2 3.1 337.2 242.2 163.2 182.5 27.5 47.0 42.7 174.0 216.5 1029.5 0.9 7.2 580.9 165.2 365.0 121.3 475.5 530.8 22.1 90.5 16.1 182.5 457.6 1.2 74.8 315.6 215.8 50.7 29.3 200.3 48.8 95.6 107.8 9.1 119.1 326.9 59.7 102.0 539.6 144.4 72.7 284.6 388.6 324.6 270.6 128.3 23.1 25.5 6.1 168.0 0.2 535.6 4.1 1.1 0.1 6.0 1.1 5.2 0.9 3.9 4.0 4.4 0.7 4.0 3.3 0.2 5.9 0.1 3.7 3.5 2.1 46.2 50.4 51.1 291.0 46.1 50.5 59.9 47.3 58.3 51.6 54.0 60.1 142.3 38.5 32.0 4.9 2.9 81.8 473.6 56.5 74.0 5.3 28.3 39.5 36.6 14.3 21.0 25.8 58.4 217.0 3.2 33.0 0.0 64.5 2.9 21.8 273.3 194.9 61.1 11.4 0.4 11.9 342.1 287.6 15.3 33.0 9.5 144.1 124.9 9.9 94.2 6.7 0.2 55.7 22.4 5.7 110.0 6.0 164.4 43.6 44.4 18.7 9.8 14.3 8.2 1.0 0.5 22.5 24.3 120.7 6.5 139.8 12.4 22.8 11.9 1.2 92.1 31.4 295.1 29.3 23.0 14.1 44.5 165.8 68.8 79.8 62.8 73.4 SERPINI1 PI12 ENSG00000163536 "Serpin family I member 1" Q99574 3 167735243-167825569 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 301.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 219.4;Excitatory neurons: 176.9;Inhibitory neurons: 228.8;Oligodendrocytes: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 29.2;Karpas-707: 29.1;U-266/84: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001565, HPA056092" Enhanced Uncertain Cytosol "Secreted in brain" NA NA 750000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA001565: AB_1079924, HPA056092: AB_2683036" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (4.09e-3)" "unprognostic (1.35e-1)" "unprognostic (6.97e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.25e-4)" "unprognostic (2.48e-1)" "unprognostic (2.61e-1)" "unprognostic (6.07e-3)" "unprognostic (2.18e-2)" "unprognostic (1.01e-1)" "unprognostic (1.58e-3)" "unprognostic (1.41e-1)" "unprognostic (2.89e-1)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" 13.1 15.8 138.8 4.1 157.7 2.3 11.7 115.9 301.4 8.4 82.1 5.1 2.2 8.6 8.2 5.5 7.9 6.3 14.0 162.0 129.1 32.1 4.1 6.4 4.6 122.8 153.6 6.9 39.5 6.9 42.8 6.7 123.9 11.8 4.4 84.4 23.0 7.4 3.2 3.1 4.4 6.1 134.6 8.7 10.8 15.8 134.5 4.4 11.2 8.1 8.2 4.9 6.0 164.8 0.8 3.5 5.5 0.4 10.3 2.2 0.3 1.9 2.7 1.3 2.2 1.5 5.9 29.2 9.5 1.3 4.5 1.3 3.9 3.8 1.5 7.7 6.5 8.9 22.5 10.7 0.7 1.4 1.1 3.8 1.4 0.8 1.3 2.9 0.4 10.5 18.9 29.1 1.2 2.7 0.8 1.9 3.3 4.2 4.5 2.7 0.4 3.2 11.2 1.0 2.2 13.4 3.6 6.8 8.3 12.4 10.6 4.4 1.0 5.5 0.5 0.5 10.3 23.0 28.4 18.8 4.2 7.7 3.2 1.5 0.3 0.8 9.3 0.7 6.9 22.1 9.7 10.2 0.5 25.2 6.9 8.1 0.9 9.5 0.5 7.2 27.2 5.2 138.8 157.7 115.9 301.4 162.0 129.1 122.8 153.6 123.9 134.6 134.5 164.8 49.8 6.4 1.5 43.1 10.7 3.7 13.2 6.4 14.2 219.4 3.6 14.1 8.2 1.5 6.7 5.5 14.6 6.1 6.2 0.7 7.9 1.8 0.4 2.0 1.0 16.0 4.8 7.4 176.9 18.0 6.0 8.9 2.6 1.7 2.5 2.3 3.9 0.6 2.3 5.0 228.8 0.3 73.2 0.6 3.2 2.4 4.1 0.9 7.2 25.3 1.2 78.0 2.1 31.2 174.7 3.0 0.0 2.6 14.6 6.7 0.0 39.9 13.6 35.4 26.3 5.2 54.7 3.0 27.4 0.5 1.7 5.1 6.2 1.1 0.3 2.3 SERPINI2 "MEPI, PANCPIN, PI14, TSA2004" ENSG00000114204 "Serpin family I member 2" O75830 3 167441789-167479004 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 133 "pancreas: 1370.0" "Cell type enhanced" "Detected in some" "Astrocytes: 37.5;Exocrine glandular cells: 93.4;Respiratory ciliated cells: 22.9" "Cancer enriched" "Detected in some" 6 "pancreatic cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "THP-1: 9.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 8.7" "Secreted to digestive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 43: THP-1 - Innate immune response" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (1.88e-2)" "unprognostic (2.23e-3)" "unprognostic (1.14e-1)" "unprognostic (5.27e-2)" "unprognostic (1.17e-2)" "unprognostic (1.29e-2)" "unprognostic (1.11e-2)" "unprognostic (2.04e-1)" "unprognostic (3.13e-1)" "unprognostic (1.76e-5)" "unprognostic (5.35e-2)" "unprognostic (4.16e-2)" 0.1 0.1 3.7 0.0 2.9 0.4 0.1 4.4 1.5 0.2 10.2 0.1 1.0 0.2 0.2 0.2 3.9 0.0 0.5 2.5 3.7 0.2 0.0 1.0 0.1 9.6 7.7 0.5 1370.0 0.0 0.4 0.0 7.1 0.2 0.0 0.0 0.4 0.0 0.0 0.1 1.9 0.1 9.4 0.2 0.3 0.1 4.3 0.0 0.0 0.2 0.1 0.1 0.1 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 9.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.7 2.9 4.4 1.5 2.5 3.7 9.6 7.7 7.1 9.4 4.3 5.8 0.0 0.0 1.1 37.5 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 5.9 0.1 0.1 0.0 0.0 3.6 93.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 1.2 0.0 0.0 2.0 0.9 4.8 0.0 0.0 0.0 0.0 0.7 0.0 22.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 SETDB1 "ESET, KG1T, KIAA0067, KMT1E, TDRD21" ENSG00000143379 "SET domain bifurcated histone lysine methyltransferase 1" Q15047 1 150926263-150964744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 6 "U-698: 341.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018142, HPA058484" Uncertain Supported Nucleoplasm,Vesicles Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm Vesicles "HPA018142: AB_1856757, HPA058484: AB_2683731" "unprognostic (1.07e-1)" "unprognostic (4.08e-1)" "unprognostic (8.02e-2)" "unprognostic (2.24e-3)" "unprognostic (1.65e-2)" "unprognostic (9.57e-2)" "prognostic unfavorable (8.88e-4)" "unprognostic (6.03e-2)" "unprognostic (9.94e-3)" "unprognostic (7.13e-2)" "unprognostic (1.21e-1)" "unprognostic (6.65e-2)" "prognostic unfavorable (4.25e-4)" "unprognostic (1.59e-1)" "unprognostic (3.93e-2)" "unprognostic (3.14e-2)" "unprognostic (1.14e-1)" 13.5 11.3 7.1 15.2 8.2 18.1 16.7 12.8 8.9 14.4 8.7 13.4 12.5 18.1 13.1 11.8 15.3 11.5 8.2 6.7 7.9 11.7 11.5 13.4 19.6 8.2 7.6 19.4 13.3 15.7 8.6 17.7 7.6 11.4 15.5 14.2 12.3 12.2 16.4 14.4 13.7 16.5 6.0 19.9 13.4 25.1 8.4 21.6 15.5 11.7 20.3 13.1 12.7 10.3 22.9 26.3 37.1 24.6 17.5 23.2 61.7 18.6 21.2 26.2 22.2 17.9 31.1 44.9 24.9 20.7 10.4 28.1 35.0 20.0 20.7 21.8 43.3 25.5 27.3 20.8 24.7 45.3 23.2 30.5 22.0 21.8 34.8 26.6 31.2 28.3 43.4 35.6 18.9 44.1 31.6 26.4 51.1 32.1 20.6 36.3 24.3 33.4 20.1 25.9 27.1 49.1 28.4 32.9 22.5 44.5 35.7 60.4 21.2 15.3 15.7 17.0 26.3 36.6 42.3 341.6 15.7 15.7 15.1 6.9 8.3 5.7 5.8 11.6 6.1 6.1 5.3 6.6 9.7 8.3 5.7 5.9 4.8 6.3 8.5 6.5 3.5 4.3 7.1 8.2 12.8 8.9 6.7 7.9 8.2 7.6 7.6 6.0 8.4 10.3 8.5 6.4 14.0 15.3 15.3 5.5 9.3 6.6 10.2 11.0 9.8 10.7 5.5 10.0 7.8 7.3 18.8 13.9 8.8 6.6 3.9 7.6 26.1 10.8 13.3 8.3 3.6 9.2 19.6 5.7 8.5 9.1 10.2 10.7 7.6 17.9 11.4 8.1 9.9 6.7 19.4 9.7 12.2 17.2 5.1 31.0 10.2 13.9 1.8 23.4 14.4 6.2 14.4 15.6 23.5 8.1 9.5 9.8 8.9 8.2 7.6 6.4 11.0 10.4 6.6 10.2 10.3 24.4 15.9 10.9 5.1 10.0 10.2 14.6 10.7 7.8 SEZ6L2 "FLJ90517, PSK-1" ENSG00000174938 "Seizure related 6 homolog like 2" Q6UXD5 16 29871159-29899547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 101.6;pituitary gland: 91.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 236.6;Cone photoreceptor cells: 185.6;Enteroendocrine cells: 132.5;Horizontal cells: 188.4;Rod photoreceptor cells: 230.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064471 Enhanced NA NA 5600000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA064471: AB_2685271" "unprognostic (2.56e-2)" "prognostic unfavorable (7.46e-4)" "prognostic unfavorable (1.31e-4)" "unprognostic (2.11e-1)" "prognostic unfavorable (5.24e-4)" "unprognostic (1.27e-1)" "unprognostic (1.67e-2)" "unprognostic (2.71e-2)" "unprognostic (8.22e-2)" "unprognostic (1.85e-1)" "unprognostic (1.43e-3)" "unprognostic (8.31e-2)" "unprognostic (1.04e-1)" "unprognostic (8.22e-2)" "unprognostic (2.30e-1)" "unprognostic (2.12e-1)" "unprognostic (1.08e-1)" 4.6 23.2 47.3 1.4 43.6 0.1 4.5 37.0 101.6 11.8 0.0 4.5 10.3 9.0 0.7 1.1 4.0 9.6 2.3 43.7 93.1 7.8 0.6 4.5 0.9 69.2 29.2 5.4 41.2 21.3 91.9 3.0 62.5 14.4 3.4 25.8 22.1 4.3 1.0 2.4 5.8 4.1 21.1 1.9 16.6 11.2 46.4 0.4 1.0 0.0 1.4 3.1 1.8 57.3 1.4 11.6 0.9 11.0 0.1 0.5 7.7 14.4 6.7 13.3 7.3 17.2 53.8 5.8 76.7 17.5 11.1 4.9 4.4 3.4 4.0 0.1 9.6 0.9 9.2 35.7 28.7 0.0 33.9 32.3 6.5 15.8 4.3 48.1 1.0 5.1 1.8 34.5 6.7 59.4 0.2 0.1 17.2 19.6 19.8 0.0 0.0 1.6 12.1 5.1 51.3 41.2 4.9 36.5 2.3 9.1 34.3 51.3 0.6 44.3 21.6 0.3 0.9 3.9 3.6 0.3 53.8 9.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 43.6 37.0 101.6 43.7 93.1 69.2 29.2 62.5 21.1 46.4 57.3 3.2 3.2 16.4 4.2 0.8 2.9 9.4 6.2 2.8 236.6 49.6 30.6 8.6 77.2 5.5 3.7 185.6 0.3 0.5 19.9 0.0 61.7 2.8 25.1 48.2 4.9 132.5 0.0 28.6 39.4 2.7 12.2 34.7 33.4 1.3 3.5 2.5 0.2 1.3 188.4 46.3 32.9 10.2 0.3 0.0 5.4 1.2 1.0 12.4 3.7 0.6 20.8 0.0 5.5 13.1 45.2 22.1 1.9 1.4 23.5 15.3 5.0 3.4 230.3 13.1 0.9 15.2 8.2 4.7 1.0 1.4 1.4 0.7 26.8 29.0 9.1 SFRP1 "FRP, FRP-1, SARP2" ENSG00000104332 "Secreted frizzled related protein 1" Q8N474 8 41261962-41309473 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 299.3;choroid plexus: 509.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 710.9;Breast myoepithelial cells: 1158.6;Cardiomyocytes: 266.3;Leydig cells: 578.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 3203.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008116, HPA064870" Approved Approved Nucleoli,Cytosol "Secreted in other tissues" Yes No 1300000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 35: Glandular cells - Unknown function" Nucleoli Cytosol "CAB008116: AB_2187070, HPA064870: AB_2685376" "unprognostic (1.23e-3)" "unprognostic (7.01e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-1)" "unprognostic (7.13e-2)" "prognostic favorable (1.55e-4)" "unprognostic (1.79e-1)" "unprognostic (2.69e-3)" "unprognostic (2.15e-2)" "unprognostic (4.67e-3)" "unprognostic (3.52e-3)" "unprognostic (4.74e-2)" "unprognostic (1.72e-2)" "unprognostic (1.75e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (3.12e-4)" 88.4 12.9 9.2 10.5 12.7 1.4 299.3 18.2 15.0 203.7 509.2 24.5 12.2 132.5 1.8 26.1 98.5 61.3 124.8 29.4 8.5 115.3 6.1 4.7 4.0 29.9 10.5 46.8 6.2 1.4 1.2 19.5 29.7 42.6 30.1 2.2 236.9 102.3 2.6 55.4 18.9 82.9 7.7 21.4 24.4 28.4 10.8 3.1 12.7 32.8 3.2 44.9 95.6 24.7 0.1 29.0 75.9 1.9 67.5 3.9 14.5 132.9 694.5 197.9 187.2 0.0 17.8 0.0 0.6 0.7 15.8 0.9 10.8 53.7 277.6 0.0 2.3 0.0 0.0 0.0 6.4 0.0 0.7 11.8 255.9 19.9 19.3 3203.5 6.2 0.2 0.0 0.0 3.7 0.0 0.0 0.2 205.8 0.1 0.3 0.0 15.7 0.0 422.6 0.0 4.1 18.5 5.5 0.0 41.5 264.7 0.1 2.1 1.9 0.1 19.6 0.2 18.3 0.0 0.0 0.0 0.2 0.0 279.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.7 18.2 15.0 29.4 8.5 29.9 10.5 29.7 7.7 10.8 24.7 8.4 0.0 0.0 2.0 1.2 11.2 134.0 1.4 147.4 1.8 710.9 1158.6 266.3 0.0 0.7 62.5 2.1 2.2 9.1 0.0 80.3 4.4 5.0 3.0 131.6 21.0 0.0 0.0 0.2 0.0 82.0 229.5 16.8 3.4 0.0 19.3 53.6 0.3 2.0 1.7 12.1 0.0 0.0 0.3 4.0 25.7 578.4 4.0 99.6 0.0 0.0 76.2 0.0 7.5 20.6 0.1 0.0 130.1 2.1 29.7 0.0 3.2 0.0 1.8 0.0 34.9 18.0 2.3 16.8 53.7 5.5 0.8 7.3 72.6 0.0 9.3 SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 4 "Fibroblasts: 806.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "AF22: 229.1;ASC diff: 85.2;HSkMC: 140.2;NTERA-2: 318.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" 188.2 16.0 4.9 84.6 4.0 0.3 154.9 3.6 6.3 23.2 11.2 72.2 18.4 12.0 22.2 212.7 62.1 318.8 6.2 12.3 13.8 4.5 0.3 62.5 11.8 4.5 3.7 8.3 45.1 7.0 72.5 0.4 4.6 56.5 44.3 2.3 83.4 70.5 6.5 80.5 57.3 89.5 3.8 0.7 34.4 1.5 2.2 9.6 92.3 38.7 3.6 306.7 63.0 12.3 0.0 0.0 229.1 0.2 85.2 15.1 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 140.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 318.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.1 0.1 0.0 8.1 0.2 0.0 0.0 0.4 0.1 0.0 12.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.0 3.6 6.3 12.3 13.8 4.5 3.7 4.6 3.8 2.2 12.3 15.5 3.2 0.6 9.4 0.5 115.5 0.8 0.0 5.7 0.0 3.7 7.9 0.3 0.0 1.9 0.0 0.0 0.1 2.0 0.0 0.0 0.2 0.0 0.1 0.1 11.8 0.0 0.0 0.7 0.0 0.2 806.1 38.7 0.3 1.3 0.0 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.0 175.0 0.5 4.1 5.0 119.2 0.0 0.6 0.0 0.0 0.5 0.1 0.1 0.0 7.2 4.1 0.7 0.0 0.1 2.9 0.0 0.0 6.7 59.4 0.0 0.1 6.9 106.0 0.1 8.6 0.0 0.0 0.9 SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" 29.1 15.6 2.3 1.4 3.0 0.8 60.0 2.7 4.5 619.9 2.1 4.4 1.2 467.1 18.7 2.3 214.0 17.3 22.4 2.5 4.6 4.3 0.6 14.7 7.3 4.0 4.8 79.2 5.0 2.8 20.5 0.2 3.2 16.1 2.6 2.3 6.5 43.9 4.1 1.5 1.4 87.9 4.0 13.9 2.3 16.8 2.7 1.6 14.9 7.0 2.0 37.4 61.0 3.9 0.0 1.8 2.1 0.0 10.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 2.2 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 1.5 0.1 0.3 0.0 3.9 0.5 0.4 0.0 0.7 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.7 0.0 0.8 1.2 0.1 0.4 0.1 0.1 0.2 3.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 2.7 4.5 2.5 4.6 4.0 4.8 3.2 4.0 2.7 3.9 5.5 0.0 1.8 0.3 0.7 1.0 1.5 0.1 0.6 0.0 0.5 2.3 1.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 1.0 22.5 472.1 4.6 0.0 0.0 0.0 0.5 0.3 196.4 0.0 14.1 0.0 102.8 3.3 0.1 0.2 0.0 0.5 0.0 0.0 0.0 4.4 2.8 41.7 7.1 0.0 2.8 0.0 2.7 0.0 17.6 0.2 0.1 0.0 188.4 0.0 2.4 0.0 1.8 0.0 0.3 0.0 30.5 25.3 0.2 0.4 0.1 1.6 0.3 9.2 1.2 0.1 0.5 SFRP5 SARP3 ENSG00000120057 "Secreted frizzled related protein 5" Q5T4F7 10 97766751-97771999 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 98.7;heart muscle: 78.7;intestine: 36.4;pancreas: 143.2" "Cell type enriched" "Detected in some" 7 "Cholangiocytes: 273.1" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 30.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "naive CD8 T-cell: 3.6" "Lineage enriched" "Detected in single" 4 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "A549: 2.5;CACO-2: 12.4;RPMI-8226: 4.5;SCLC-21H: 2.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 120.7" "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 39: CACO-2 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (2.63e-4)" "unprognostic (3.03e-3)" "unprognostic (6.74e-2)" "unprognostic (3.43e-2)" "unprognostic (9.85e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" "unprognostic (3.19e-1)" "unprognostic (2.85e-1)" "unprognostic (8.83e-2)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (4.51e-9)" "unprognostic (1.67e-2)" "unprognostic (1.57e-1)" "unprognostic (9.17e-2)" "unprognostic (1.62e-1)" 2.9 9.6 2.8 0.3 3.9 0.3 2.4 1.6 0.6 3.5 98.7 36.4 29.8 1.8 2.2 2.0 2.2 4.1 78.7 5.6 7.5 0.4 8.8 3.4 0.3 3.6 8.3 0.6 143.2 0.0 0.9 0.0 3.6 6.8 0.5 0.2 2.8 4.0 1.3 3.1 26.3 0.4 1.6 0.1 10.5 0.8 14.7 0.1 1.0 2.9 0.1 3.2 4.9 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 4.5 0.0 0.0 2.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.8 0.0 0.2 2.8 3.9 1.6 0.6 5.6 7.5 3.6 8.3 3.6 1.6 14.7 0.2 0.0 3.2 3.6 0.3 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.0 7.8 273.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.1 0.6 0.0 0.0 0.2 16.8 0.0 3.2 0.0 0.0 0.0 0.0 2.2 0.7 0.0 0.0 0.3 1.3 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.2 3.3 2.5 0.0 0.0 0.0 37.8 0.0 0.0 0.2 0.0 1.2 0.4 0.1 5.9 0.0 0.0 0.0 0.1 0.0 0.5 0.0 SFTA2 SFTPG ENSG00000196260 "Surfactant associated 2" Q6UW10 6 30931353-30955636 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 49.1;lung: 179.1" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 535.2;Alveolar cells type 2: 806.4" "Cancer enhanced" "Detected in many" "lung cancer: 121.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "CACO-2: 12.0;CAPAN-2: 5.5" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 39: CACO-2 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (5.82e-2)" "unprognostic (1.16e-1)" "unprognostic (7.20e-3)" "unprognostic (6.64e-2)" "unprognostic (3.12e-1)" "unprognostic (1.34e-1)" "unprognostic (6.37e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (1.16e-1)" "unprognostic (3.96e-4)" "unprognostic (8.84e-2)" "unprognostic (2.36e-2)" "unprognostic (5.39e-3)" "unprognostic (7.95e-2)" 0.2 0.2 0.5 0.1 0.6 0.0 0.3 0.5 0.9 4.7 0.5 0.1 0.0 0.4 0.0 49.1 0.6 0.8 0.2 0.5 0.5 6.1 0.4 179.1 0.2 0.6 0.6 0.4 4.4 0.3 0.1 0.2 0.6 0.2 0.0 0.1 4.1 0.1 0.6 0.1 0.2 0.1 0.6 0.3 7.9 1.7 0.5 0.1 2.0 0.1 0.2 0.2 21.6 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.5 0.9 0.5 0.5 0.6 0.6 0.6 0.6 0.5 0.6 0.2 535.2 806.4 0.0 1.0 0.1 0.1 0.0 0.0 0.5 0.9 0.3 0.0 140.2 111.8 53.3 0.0 0.1 0.0 0.0 3.9 22.7 3.8 76.1 2.5 2.1 0.0 0.0 0.0 35.6 0.0 0.8 13.7 23.0 12.6 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 13.7 0.3 1.3 0.0 0.0 0.1 2.8 0.0 0.0 0.1 94.2 0.0 0.4 0.5 0.3 0.0 0.8 8.1 0.1 0.0 1.1 0.4 7.5 1.7 2.8 0.0 0.0 1.7 0.1 0.1 1.1 SFTPA1 "COLEC4, SFTP1, SP-A, SP-A1" ENSG00000122852 "Surfactant protein A1" Q8IWL2 10 79610939-79615455 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Gaseous exchange" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1048 "lung: 7084.8" "Cell type enriched" "Detected in some" 11 "Alveolar cells type 2: 13480.7" "Cancer enriched" "Detected in some" 25 "lung cancer: 706.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 27 "plasmacytoid DC: 2.7" "Lineage enriched" "Detected in single" 27 "dendritic cells: 2.7" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 43.2" "CAB016793, HPA042638, HPA045752, HPA049368" Supported "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB016793: , HPA042638: AB_2678095, HPA045752: AB_2679442, HPA049368: AB_2680731" "unprognostic (5.83e-4)" "unprognostic (1.17e-1)" "unprognostic (3.38e-2)" "unprognostic (4.24e-1)" "unprognostic (3.47e-2)" "unprognostic (9.09e-2)" 0.5 6.7 0.1 2.6 0.1 0.0 0.5 0.3 0.3 0.9 0.0 0.3 0.0 0.1 0.0 0.2 0.2 0.0 0.8 0.2 0.0 0.2 0.9 7084.8 0.0 0.0 0.0 6.3 0.7 0.0 0.3 1.4 0.0 1.0 0.0 0.0 0.2 4.8 0.8 0.8 0.4 0.0 0.0 4.9 3.8 0.3 0.0 1.5 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.7 0.1 0.0 0.0 0.0 0.0 43.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 7.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.1 0.1 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1160.3 13480.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 183.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 454.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.2 0.0 0.0 0.0 SFTPA2 "COLEC5, SP-A2" ENSG00000185303 "Surfactant protein A2" Q8IWL1 10 79555852-79560407 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 404 "lung: 10798.8" "Cell type enriched" "Detected in some" 10 "Alveolar cells type 2: 16905.3" "Cancer enriched" "Detected in many" 21 "lung cancer: 863.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "BEWO: 7.3;NB-4: 8.3;RPMI-8226: 26.1;U-2197: 14.7" "CAB002439, HPA042638, HPA045752, HPA049368" Enhanced "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 19: Lung - Lung function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB002439: AB_564143, HPA042638: AB_2678095, HPA045752: AB_2679442, HPA049368: AB_2680731" "unprognostic (2.51e-1)" "unprognostic (4.87e-2)" "unprognostic (4.99e-2)" "unprognostic (4.38e-2)" "unprognostic (4.29e-2)" "unprognostic (1.05e-1)" "unprognostic (5.78e-2)" "unprognostic (5.08e-1)" "unprognostic (4.94e-2)" "unprognostic (1.68e-3)" "unprognostic (3.10e-1)" "unprognostic (3.56e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" "unprognostic (4.69e-3)" 0.7 12.1 0.4 4.6 0.6 0.0 1.0 3.1 0.9 1.4 0.0 1.4 0.0 0.2 0.1 0.4 0.2 0.0 1.1 0.5 0.4 0.4 1.1 10798.8 0.0 1.2 0.0 6.5 1.3 0.0 0.4 2.3 1.3 26.7 2.6 0.2 0.4 8.3 1.0 1.1 0.5 0.1 0.0 6.7 10.5 0.5 0.3 2.7 0.8 0.0 0.1 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 8.3 0.4 0.0 0.0 0.2 0.0 26.1 0.0 0.3 0.3 0.3 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.2 14.7 0.1 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.6 3.1 0.9 0.5 0.4 1.2 0.0 1.3 0.0 0.3 0.6 0.0 1593.0 16905.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 329.9 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.2 0.0 0.0 22.3 1.8 0.0 0.3 3.1 0.0 22.0 0.0 0.2 431.4 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 1.2 2.0 0.0 0.0 1.0 0.0 0.1 135.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.7 0.0 2.4 0.1 SFTPB "SFTP3, SP-B" ENSG00000168878 "Surfactant protein B" P07988 2 85657314-85668741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 32 "lung: 3566.0" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 2: 15343.4" "Cancer enriched" "Detected in many" 5 "lung cancer: 1306.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 2.8;NB-4: 3.5;U-2197: 6.7;U-266/70: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002440, HPA034820, HPA062148" Enhanced "Secreted in other tissues" NA NA 80000000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "CAB002440: AB_564142, HPA034820: AB_2674347, HPA062148: AB_2684697" "unprognostic (6.46e-3)" "unprognostic (4.94e-2)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.71e-6)" "unprognostic (2.25e-3)" "unprognostic (4.57e-3)" "unprognostic (8.57e-3)" "unprognostic (6.45e-3)" "unprognostic (1.13e-1)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (2.99e-6)" "unprognostic (2.37e-1)" "unprognostic (1.09e-1)" "unprognostic (7.90e-2)" "unprognostic (4.38e-2)" 0.8 4.4 1.5 2.2 1.4 0.4 0.5 1.7 3.0 0.5 1.1 0.5 0.3 0.2 0.7 0.4 0.3 0.2 1.4 1.3 2.1 2.1 1.2 3566.0 0.3 1.4 1.1 11.0 0.9 0.2 5.4 1.5 1.5 1.2 0.4 2.9 0.5 2.0 1.2 0.8 0.7 0.1 0.8 4.1 5.1 0.4 1.4 0.3 113.1 0.3 0.2 0.2 0.4 1.5 0.1 0.2 0.2 0.5 0.3 0.5 2.8 0.2 0.2 0.1 0.0 0.3 0.6 0.0 0.2 0.0 0.3 2.0 0.2 0.0 0.0 0.3 0.2 0.3 0.7 0.3 0.1 0.1 1.4 0.0 0.3 0.2 0.1 0.5 0.0 0.4 0.3 0.4 0.1 0.3 1.1 3.5 1.6 0.5 0.4 1.3 0.2 0.3 0.2 0.3 0.4 0.3 0.0 0.4 0.2 0.3 0.3 0.3 0.0 0.2 0.6 6.7 0.1 2.4 0.6 0.2 0.6 0.5 0.1 0.3 0.6 0.2 0.2 1.1 0.1 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.6 0.2 0.7 0.2 0.4 0.4 1.5 1.4 1.7 3.0 1.3 2.1 1.4 1.1 1.5 0.8 1.4 1.5 0.0 3650.6 15343.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.5 0.0 1930.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 14.4 0.0 0.0 0.2 0.2 0.0 26.9 0.0 0.0 262.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 16.2 0.0 0.3 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 185.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 36.5 0.0 0.0 0.2 SFTPC "BRICD6, PSP-C, SFTP2, SMDP2, SP-C" ENSG00000168484 "Surfactant protein C" P11686 8 22156913-22164479 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 795 "lung: 18462.2" "Cell type enriched" "Detected in some" 12 "Alveolar cells type 2: 107013.9" "Cancer enriched" "Detected in some" 218 "lung cancer: 226.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 9.5;NB-4: 12.4;SCLC-21H: 5.1;U-2197: 24.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010928 Enhanced "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA010928: AB_1857425" "unprognostic (1.84e-1)" "unprognostic (1.96e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (2.97e-1)" "unprognostic (4.97e-2)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (1.32e-2)" 2.6 23.2 10.3 10.3 12.1 0.0 0.9 10.8 15.8 1.6 8.3 1.3 0.0 0.4 0.3 0.9 0.4 0.0 2.8 10.2 10.6 1.0 2.8 18462.2 0.0 11.9 11.2 21.5 1.7 0.0 1.1 4.7 10.8 3.0 0.0 0.0 0.8 8.9 2.0 3.1 2.3 0.0 10.3 14.0 6.4 2.8 11.4 0.0 4.3 0.1 0.2 0.1 0.9 15.3 0.0 0.1 0.0 0.0 0.5 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 12.4 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 5.1 0.4 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.1 0.1 24.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 12.1 10.8 15.8 10.2 10.6 11.9 11.2 10.8 10.3 11.4 15.3 0.0 8535.2 107013.9 0.7 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 1416.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 67.8 0.0 0.0 0.9 0.0 0.0 174.6 0.0 0.0 986.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.3 30.4 0.0 106.6 23.2 0.0 0.0 0.0 0.0 0.5 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 339.6 0.0 6.6 0.0 0.3 0.1 0.1 0.0 0.6 0.0 163.4 0.4 0.0 0.1 SFTPD "COLEC7, SFTP4, SP-D" ENSG00000133661 "Surfactant protein D" P35247 10 79937467-79982614 "Predicted secreted proteins" "Gaseous exchange, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "lung: 507.9" "Cell type enriched" "Detected in many" 4 "Alveolar cells type 2: 1863.1" "Cancer enriched" "Detected in many" 16 "lung cancer: 106.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 10.0;non-classical monocyte: 36.3" "Lineage enriched" "Detected in many" 18 "monocytes: 36.3" "Cell line enhanced" "Detected in some" "BEWO: 1.1;HaCaT: 1.0;hTCEpi: 3.2;MCF7: 1.3;U-2197: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB004578, HPA044582, HPA056768" Enhanced "Secreted in other tissues" NA NA 8200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "CAB004578: AB_628276, HPA044582: AB_2679004, HPA056768: AB_2683232" "unprognostic (3.81e-5)" "unprognostic (7.00e-2)" "unprognostic (1.19e-2)" "unprognostic (1.41e-2)" "unprognostic (4.78e-2)" "unprognostic (1.29e-1)" "unprognostic (1.66e-3)" "unprognostic (6.83e-2)" "unprognostic (3.85e-1)" "unprognostic (2.23e-1)" "unprognostic (5.29e-2)" "unprognostic (2.57e-1)" "unprognostic (4.70e-2)" "unprognostic (2.57e-2)" "unprognostic (2.38e-1)" "unprognostic (1.45e-1)" "unprognostic (8.86e-2)" 1.1 1.8 2.2 0.4 2.4 19.7 0.9 1.7 2.5 1.3 2.3 1.0 0.1 0.5 1.3 1.8 1.8 0.9 1.1 2.2 2.4 1.6 1.0 507.9 0.0 1.7 2.0 1.1 4.2 2.0 3.4 0.7 1.8 1.4 0.1 0.3 1.0 1.2 0.2 5.0 0.4 0.4 1.4 0.6 1.1 1.3 2.6 0.5 5.8 0.2 0.2 0.3 2.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.8 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.1 0.3 0.3 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 10.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 36.3 0.0 0.0 0.9 2.2 2.4 1.7 2.5 2.2 2.4 1.7 2.0 1.8 1.4 2.6 1.7 0.3 439.1 1863.1 1.0 0.2 0.9 1.3 7.8 1.2 1.7 1.4 1.8 0.7 0.0 38.0 5.5 0.0 0.1 0.0 0.0 1.9 1.4 7.4 0.6 0.1 1.5 0.0 0.0 4.9 5.8 3.0 4.4 0.0 0.9 20.2 1.6 0.4 0.7 0.1 0.0 3.5 0.0 0.0 0.0 2.7 12.2 1.2 2.9 0.0 1.9 0.6 2.8 0.0 0.0 0.6 2.0 0.1 0.4 0.0 0.8 0.0 0.2 9.6 0.5 0.0 1.8 0.4 0.4 0.3 0.6 1.8 0.1 4.3 0.1 0.1 0.6 SFXN4 SLC56A4 ENSG00000183605 "Sideroflexin 4" Q6P4A7 10 119140767-119165714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018028, HPA020872" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" Vesicles "HPA018028: AB_1856792, HPA020872: AB_1856793" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (3.61e-1)" "unprognostic (1.12e-1)" "unprognostic (1.27e-2)" "unprognostic (9.49e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (6.84e-2)" "unprognostic (4.56e-2)" "unprognostic (8.58e-2)" "unprognostic (2.94e-2)" "unprognostic (1.70e-3)" "unprognostic (4.22e-3)" "unprognostic (1.43e-1)" "unprognostic (6.21e-3)" "unprognostic (3.07e-3)" 13.3 35.9 9.9 10.1 12.5 16.4 14.1 12.8 13.6 14.2 17.0 21.9 20.4 11.1 13.5 19.1 14.3 8.6 33.1 10.2 12.4 24.5 36.4 8.5 14.4 11.3 12.5 16.0 33.7 23.1 21.5 8.8 11.6 18.8 22.7 5.7 27.8 13.2 51.4 11.5 17.3 12.2 10.6 20.9 17.3 11.9 11.3 11.0 24.7 59.3 17.8 16.4 13.8 12.5 26.2 27.6 8.7 41.8 10.4 19.7 33.0 16.3 19.8 21.0 21.8 45.9 43.2 62.6 15.6 14.9 22.4 48.2 57.5 36.3 24.3 33.1 65.7 28.7 18.4 47.3 37.1 49.7 28.8 21.1 34.4 22.0 63.8 19.5 25.0 46.5 45.2 17.5 13.6 29.6 53.8 60.4 11.8 50.2 32.5 51.7 27.1 49.0 24.3 17.3 25.2 13.9 10.8 42.2 61.9 11.1 26.0 28.4 11.5 10.6 21.9 19.8 37.6 42.6 53.0 56.3 16.2 72.6 7.2 2.5 18.1 1.9 6.5 19.5 10.8 12.5 7.9 7.1 21.2 7.0 12.1 9.8 2.2 7.3 15.9 10.6 6.0 11.1 9.9 12.5 12.8 13.6 10.2 12.4 11.3 12.5 11.6 10.6 11.3 12.5 8.0 6.4 5.6 29.0 16.9 12.0 25.8 39.9 23.3 7.9 17.8 18.2 36.2 12.8 19.1 14.7 2.1 37.6 6.2 13.2 58.7 28.4 27.4 7.6 8.9 8.4 18.0 33.6 22.3 23.8 25.8 12.4 14.3 7.9 5.7 28.5 7.1 31.5 29.2 6.7 29.1 24.7 30.5 17.6 5.0 69.3 8.7 13.1 12.4 8.4 11.3 7.7 10.3 22.1 19.5 17.6 12.1 13.5 31.9 28.0 29.8 65.6 13.5 11.3 6.6 22.3 10.6 27.7 15.2 26.9 9.1 21.9 9.2 44.5 45.8 20.5 SFXN5 "BBG-TCC, SLC56A5" ENSG00000144040 "Sideroflexin 5" Q8TD22 2 72942036-73075619 "Predicted intracellular proteins, Predicted membrane proteins" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 63.6" "Cell type enhanced" "Detected in many" "Astrocytes: 405.2;Early spermatids: 96.4;Late spermatids: 168.4" "Cancer enhanced" "Detected in all" "glioma: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015473, HPA056866" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 11: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Mitochondria" "HPA015473: AB_1856794, HPA056866: AB_2683261" "unprognostic (7.75e-2)" "unprognostic (1.64e-2)" "unprognostic (1.40e-1)" "unprognostic (2.71e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-3)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "prognostic favorable (2.26e-6)" "unprognostic (1.57e-1)" "unprognostic (8.51e-2)" "unprognostic (3.50e-1)" "unprognostic (3.23e-1)" "unprognostic (3.97e-1)" "unprognostic (1.43e-2)" 3.2 11.7 52.1 4.6 45.5 13.7 2.5 40.0 63.6 3.2 21.9 6.1 6.9 3.1 16.6 3.1 4.2 4.0 3.5 48.0 45.2 11.4 29.4 3.6 3.9 51.5 49.2 2.6 2.4 2.0 3.5 3.7 41.4 4.2 5.7 6.2 2.2 4.5 7.7 4.5 6.5 3.9 42.6 5.6 4.6 2.4 57.0 4.9 3.7 4.6 3.0 3.8 2.3 37.4 4.2 9.1 13.7 11.5 3.0 5.0 5.4 8.4 5.4 13.3 6.9 13.7 10.7 2.3 8.8 8.9 9.2 3.7 10.8 11.1 6.0 10.2 6.7 10.7 11.0 18.7 4.4 5.9 11.1 5.8 3.5 9.0 1.1 4.9 7.4 3.2 9.5 2.9 4.3 8.7 1.5 9.5 17.1 8.1 6.6 10.6 12.2 3.1 8.1 10.5 9.0 2.7 8.6 4.3 3.5 7.7 2.2 5.3 6.8 4.1 13.5 6.1 10.2 4.0 4.1 3.1 15.0 10.3 5.3 4.7 6.0 3.5 0.6 2.6 0.9 1.6 0.3 0.7 2.7 2.4 0.4 0.5 4.6 4.3 3.2 1.9 0.7 1.7 52.1 45.5 40.0 63.6 48.0 45.2 51.5 49.2 41.4 42.6 57.0 37.4 7.1 0.0 4.4 405.2 4.8 4.7 4.3 7.6 4.6 26.8 6.9 5.5 5.8 7.2 4.8 36.8 33.3 12.4 6.8 18.4 3.9 5.1 96.4 5.1 13.1 7.6 13.8 13.7 84.4 9.1 2.4 8.9 9.2 11.2 0.0 42.8 9.3 61.3 12.4 20.2 57.4 8.6 2.0 8.7 9.6 168.4 10.5 9.6 8.8 43.1 19.7 65.8 10.3 40.2 29.9 8.0 6.5 11.3 7.1 3.6 17.5 22.2 3.2 42.3 13.1 12.2 8.8 11.2 15.7 7.3 9.2 4.2 6.3 15.9 8.8 2.3 SGCA "A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1" ENSG00000108823 "Sarcoglycan alpha" Q16586 17 50164214-50175928 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 155.6;skeletal muscle: 522.4;tongue: 237.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 128.4;Early spermatids: 162.6;Late spermatids: 705.4;Skeletal myocytes: 195.2" "Cancer enhanced" "Detected in many" "prostate cancer: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 1.4;memory B-cell: 3.3;myeloid DC: 2.2;naive B-cell: 3.3;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 15 "B-cells: 3.3;dendritic cells: 2.2;monocytes: 1.8" "Cell line enriched" "Detected in some" 16 "LHCN-M2: 78.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007537 Uncertain "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA007537: AB_1079944" "unprognostic (1.34e-1)" "unprognostic (2.30e-2)" "unprognostic (1.89e-3)" "unprognostic (1.25e-1)" "unprognostic (9.87e-2)" "unprognostic (2.43e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-2)" "unprognostic (1.15e-1)" "unprognostic (1.91e-1)" "unprognostic (7.01e-2)" "unprognostic (2.57e-1)" "unprognostic (2.07e-3)" "unprognostic (4.96e-2)" "unprognostic (2.16e-1)" "unprognostic (2.95e-1)" "unprognostic (1.15e-2)" 12.2 1.5 1.8 7.3 2.9 0.0 4.3 3.5 2.2 10.1 1.0 53.7 5.3 36.9 1.6 22.8 18.1 11.9 155.6 1.4 1.5 2.7 4.8 29.7 0.5 1.6 1.5 5.1 1.3 0.8 0.9 6.7 1.8 26.0 3.2 0.1 8.7 27.1 522.4 12.4 14.8 23.0 1.1 3.4 24.1 1.7 1.7 2.3 3.4 237.0 0.4 46.5 11.6 4.7 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.1 0.0 1.4 0.0 3.3 0.0 0.0 2.2 3.3 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.4 1.8 2.9 3.5 2.2 1.4 1.5 1.6 1.5 1.8 1.1 1.7 4.7 1.1 0.0 0.0 0.0 1.3 8.7 0.5 0.4 0.0 0.6 0.1 0.5 128.4 0.0 0.3 0.0 0.0 0.5 1.4 0.0 0.0 0.6 162.6 0.0 0.2 4.6 0.0 0.0 0.0 5.8 0.1 30.4 0.5 0.0 0.0 0.0 2.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 16.5 705.4 3.1 0.8 8.8 1.9 1.9 0.0 0.0 0.0 0.1 4.1 0.0 3.8 0.1 0.6 0.0 2.1 0.0 0.0 13.1 195.2 48.2 2.3 1.9 0.1 9.9 0.3 0.9 0.0 0.0 0.2 SGIP1 DKFZp761D221 ENSG00000118473 "SH3GL interacting endocytic adaptor 1" Q9BQI5 1 66533383-66751139 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 131.4" "Group enriched" "Detected in many" 4 "Astrocytes: 390.1;Cone photoreceptor cells: 350.3;Excitatory neurons: 323.3;Inhibitory neurons: 401.5;Oligodendrocyte precursor cells: 482.0;Oligodendrocytes: 363.6;Rod photoreceptor cells: 344.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 29.9;BJ hTERT+: 38.0;fHDF/TERT166: 24.5;hTERT-RPE1: 15.8;RPTEC TERT1: 27.5;SH-SY5Y: 15.3;U-138 MG: 27.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017963 Approved Approved Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA017963: AB_10964882" "unprognostic (1.74e-2)" "unprognostic (2.77e-1)" "unprognostic (2.86e-1)" "unprognostic (1.07e-1)" "unprognostic (1.74e-1)" "unprognostic (9.04e-2)" "unprognostic (9.51e-2)" "unprognostic (7.64e-2)" "unprognostic (1.86e-1)" "unprognostic (1.61e-1)" "unprognostic (1.83e-1)" "unprognostic (1.95e-1)" "unprognostic (3.48e-7)" "unprognostic (1.77e-2)" "unprognostic (1.29e-1)" "unprognostic (4.25e-2)" "unprognostic (9.63e-2)" 7.4 4.3 12.2 1.9 15.5 0.2 2.7 6.3 17.4 10.4 0.0 3.1 1.6 10.6 4.6 2.7 3.8 4.6 5.0 15.3 5.8 18.0 0.7 8.3 0.7 5.1 5.7 1.6 0.5 0.2 7.7 1.9 5.3 5.8 1.5 131.4 1.7 5.0 2.5 1.6 2.0 3.8 1.6 0.3 3.3 4.4 5.5 0.7 8.9 1.2 0.4 2.7 5.4 10.1 0.0 0.0 0.0 0.0 0.9 5.5 0.0 29.9 38.0 2.3 3.4 0.0 0.0 0.0 0.1 24.5 0.2 0.0 0.0 0.1 4.3 0.0 0.0 1.1 0.4 0.0 6.5 0.0 0.0 4.1 0.0 2.3 0.0 15.8 11.3 0.2 0.0 0.0 13.8 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 27.5 0.0 0.7 15.3 0.0 0.0 0.0 0.6 0.0 1.1 1.9 27.3 0.0 0.7 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 15.5 6.3 17.4 15.3 5.8 5.1 5.7 5.3 1.6 5.5 10.1 5.0 0.0 0.0 390.1 0.1 1.0 0.3 0.4 0.0 89.8 0.2 4.7 2.5 2.8 0.0 9.2 350.3 0.1 0.0 0.1 7.9 0.5 0.6 2.9 7.8 13.8 0.0 0.0 323.3 0.0 0.0 15.8 0.5 5.7 10.1 0.0 0.4 0.2 0.2 74.0 401.5 0.0 0.0 0.0 1.1 1.2 2.1 0.4 10.6 48.7 0.0 49.4 0.0 482.0 363.6 0.0 0.0 11.3 0.8 0.8 0.0 0.2 0.0 344.1 13.1 3.2 32.2 0.2 0.4 0.1 1.0 0.3 0.5 0.0 0.1 0.3 SGSH "HSS, MPS3A, SFMD" ENSG00000181523 "N-sulfoglucosamine sulfohydrolase" P51688 17 80206716-80220923 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 62.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023436, HPA023451" Enhanced "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA023436: AB_1856806, HPA023451: AB_1856807" "unprognostic (4.33e-2)" "unprognostic (4.03e-2)" "unprognostic (1.06e-2)" "unprognostic (4.01e-2)" "unprognostic (4.26e-3)" "unprognostic (1.39e-3)" "prognostic unfavorable (7.71e-4)" "prognostic favorable (2.72e-4)" "unprognostic (6.08e-2)" "unprognostic (3.65e-1)" "prognostic favorable (3.10e-4)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.42e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (7.50e-2)" "unprognostic (3.68e-2)" 16.6 45.9 1.7 12.2 2.3 3.6 17.2 0.7 5.2 13.5 8.8 14.8 12.7 17.2 4.6 11.0 16.0 10.6 9.9 2.0 5.4 15.7 9.5 18.1 13.4 4.4 7.6 12.3 20.4 16.0 17.0 12.4 4.2 19.7 6.5 2.8 21.8 11.1 7.0 18.9 16.7 10.6 2.5 28.4 17.8 3.9 5.3 4.2 21.2 4.6 6.9 15.5 11.5 1.8 2.6 7.9 9.8 15.6 22.5 20.2 10.4 16.0 40.4 27.7 24.2 9.0 9.5 0.1 25.7 24.9 13.2 9.9 6.2 11.7 4.7 5.3 9.6 0.0 22.3 25.0 62.2 0.0 5.9 33.9 12.0 9.9 10.5 5.8 50.7 4.7 7.1 26.2 17.9 16.2 0.3 0.2 3.3 10.0 13.2 1.4 3.7 21.1 20.2 18.5 2.0 11.7 18.4 44.1 10.6 4.9 32.8 0.5 32.5 31.9 7.0 11.4 7.4 26.1 3.6 3.9 13.6 0.0 16.3 0.0 20.6 0.0 12.1 8.0 16.0 3.5 10.5 11.3 20.4 3.8 8.2 6.7 2.1 9.3 8.0 1.5 13.5 12.7 1.7 2.3 0.7 5.2 2.0 5.4 4.4 7.6 4.2 2.5 5.3 1.8 7.5 3.2 10.8 4.2 5.5 5.1 3.7 5.9 5.7 3.7 9.3 9.3 1.7 5.7 7.3 7.3 8.4 18.2 5.2 12.0 0.0 8.9 0.2 5.3 9.2 10.1 3.0 2.7 2.6 15.9 8.7 10.1 17.9 10.0 0.0 13.6 9.7 4.5 17.7 0.0 3.4 9.3 4.1 18.2 7.6 0.5 11.5 13.0 1.8 2.8 8.4 4.1 6.2 4.5 1.7 6.8 6.0 14.3 5.5 5.5 8.1 4.9 3.8 3.9 13.1 4.0 5.3 0.3 0.5 6.4 5.5 27.0 7.2 32.0 8.0 2.9 SH3RF3 "FLJ00204, POSH2, SH3MD4" ENSG00000172985 "SH3 domain containing ring finger 3" Q8TEJ3 2 109129205-109504634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Astrocytes: 47.0;Excitatory neurons: 108.3;Inhibitory neurons: 160.9;Microglial cells: 164.9;Oligodendrocyte precursor cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 19.8;RPMI-8226: 20.5;TIME: 23.2;U-266/84: 28.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044822, HPA048444" Approved Supported Nucleoplasm Yes No "Cluster 47: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA044822: AB_2679103, HPA048444: AB_2680396" "unprognostic (1.97e-1)" "unprognostic (8.84e-3)" "unprognostic (8.04e-2)" "unprognostic (1.91e-1)" "unprognostic (2.55e-1)" "unprognostic (1.78e-1)" "unprognostic (8.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.57e-2)" "unprognostic (1.95e-1)" "unprognostic (3.54e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-2)" 6.1 6.7 4.7 3.0 6.1 0.8 4.3 1.3 6.5 5.5 1.6 5.6 1.1 3.7 0.7 2.8 4.8 4.4 6.0 6.3 3.2 6.8 1.1 7.2 2.1 3.0 4.5 3.2 2.0 0.5 1.9 5.2 2.8 4.7 1.4 0.6 1.6 4.4 5.7 3.1 3.3 3.8 3.1 2.1 2.9 4.2 3.9 3.2 2.5 7.3 1.2 5.5 4.2 3.5 0.0 0.1 0.1 2.2 9.0 6.9 0.0 4.2 12.2 3.1 1.1 1.1 0.0 0.0 3.1 3.1 0.7 0.0 0.2 1.8 1.3 0.0 4.2 0.0 0.2 0.0 19.8 0.1 0.0 12.0 2.9 14.1 6.3 1.8 11.4 2.2 0.0 11.7 7.3 0.0 0.0 6.5 1.1 0.0 12.0 2.6 0.0 20.5 0.0 0.0 0.7 2.5 0.0 0.0 0.4 0.1 0.2 0.0 23.2 4.0 12.0 11.5 5.5 4.0 28.6 0.0 0.0 6.3 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.7 6.1 1.3 6.5 6.3 3.2 3.0 4.5 2.8 3.1 3.9 3.5 5.3 0.0 0.0 47.0 0.2 1.9 0.4 0.2 1.8 0.5 0.6 0.5 10.7 0.0 0.7 0.0 0.0 0.0 1.5 0.1 0.0 1.1 2.6 9.4 9.6 6.7 1.8 0.0 108.3 0.2 0.2 4.8 0.0 1.1 0.0 0.2 7.5 0.0 4.7 10.1 160.9 0.8 0.0 2.5 1.5 5.2 2.1 1.2 5.4 164.9 0.0 1.7 0.0 42.3 1.9 0.1 0.0 3.0 1.6 0.2 0.0 0.6 2.1 0.0 13.1 3.2 6.8 0.7 9.6 0.8 0.9 0.1 0.5 2.3 0.1 0.0 SHBG "ABP, MGC126834, MGC138391, TEBG" ENSG00000129214 "Sex hormone binding globulin" P04278 17 7613946-7633382 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 63.4" "Cell type enhanced" "Detected in some" "Early spermatids: 51.6;Late spermatids: 124.5;Proximal enterocytes: 31.1" "Cancer enriched" "Detected in some" 28 "liver cancer: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.4;Hep G2: 3.0;HSkMC: 4.3" "Not detected" "Not detected" "Secreted to blood" NA NA 9100000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.35e-3)" "unprognostic (6.47e-2)" "unprognostic (5.65e-2)" "unprognostic (2.35e-1)" "unprognostic (8.84e-2)" "unprognostic (3.08e-1)" "unprognostic (3.50e-1)" "unprognostic (2.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.32e-3)" "unprognostic (3.58e-3)" "unprognostic (2.21e-1)" "unprognostic (4.49e-2)" "unprognostic (7.83e-3)" "unprognostic (4.35e-1)" "unprognostic (5.50e-3)" "unprognostic (1.06e-1)" 0.7 1.3 1.8 0.0 1.8 0.1 0.4 1.7 2.0 0.7 1.9 0.3 5.3 0.5 0.9 0.2 0.6 0.3 0.6 1.9 1.8 3.5 63.4 0.3 0.1 1.8 1.8 0.7 0.4 0.5 0.7 0.3 1.9 0.5 0.2 0.9 0.2 0.4 0.8 0.1 7.1 0.2 1.7 0.4 0.3 12.4 1.7 0.2 0.8 0.7 0.1 0.3 0.2 1.8 0.1 2.4 2.4 0.3 4.4 2.0 0.1 0.6 0.9 0.9 0.5 0.9 0.3 0.0 0.5 0.8 1.2 0.3 0.1 0.1 0.5 0.1 0.3 0.0 0.6 3.0 1.4 0.0 0.1 4.3 0.3 1.6 0.8 0.8 0.1 0.0 0.2 0.1 0.2 0.5 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.3 0.3 0.1 0.3 1.8 0.0 0.2 0.8 0.4 0.0 0.8 0.4 0.0 0.0 0.2 0.3 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 1.7 2.0 1.9 1.8 1.8 1.8 1.9 1.7 1.7 1.8 0.2 0.0 0.0 0.7 0.5 0.0 0.3 0.1 0.0 0.4 0.5 0.6 0.5 0.0 0.2 0.0 0.0 0.4 0.0 0.2 5.9 0.5 51.6 0.4 0.6 0.1 0.0 0.0 1.0 0.2 0.1 0.4 0.0 0.2 0.0 0.6 1.1 13.8 0.3 0.0 0.9 1.3 2.0 0.8 0.0 124.5 0.9 0.5 0.0 0.0 0.0 2.4 0.0 0.5 0.6 0.1 1.3 0.7 0.0 0.3 31.1 12.8 0.4 1.3 6.6 0.2 0.3 7.2 0.8 0.0 0.0 0.3 0.1 1.1 0.5 0.3 SHC1 "p66, SHC, ShcA" ENSG00000160691 "SHC adaptor protein 1" P29353 1 154962298-154974395 "Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001844, CAB005374, CAB016305" Supported Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB005374: AB_632395, CAB016305: AB_628249, HPA001844: AB_1856826" "unprognostic (4.12e-2)" "prognostic unfavorable (6.74e-4)" "unprognostic (1.10e-2)" "unprognostic (3.77e-2)" "unprognostic (6.40e-2)" "unprognostic (4.08e-3)" "unprognostic (2.94e-3)" "prognostic unfavorable (1.92e-4)" "unprognostic (9.13e-2)" "unprognostic (1.66e-1)" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.22e-16)" "unprognostic (7.19e-2)" "unprognostic (1.40e-1)" "unprognostic (9.21e-2)" "unprognostic (1.31e-1)" 147.4 103.8 30.9 90.3 29.8 72.8 126.7 28.9 32.0 91.3 32.2 71.8 72.1 86.0 53.7 73.5 87.5 88.8 67.0 28.0 33.2 71.4 94.5 106.3 50.6 36.2 32.6 70.7 57.7 61.8 120.5 77.0 36.4 85.0 70.9 16.5 58.7 70.2 63.3 59.2 73.0 107.6 32.7 72.8 69.7 23.3 39.5 47.4 86.4 56.2 52.8 96.6 83.2 30.4 110.8 223.7 168.9 272.3 180.6 359.3 88.6 393.5 355.3 223.6 168.7 80.2 258.5 59.3 314.0 476.4 64.1 92.9 45.5 389.6 200.2 72.7 25.0 152.0 185.7 143.9 471.1 49.3 164.8 538.3 452.4 279.4 344.0 605.8 497.7 25.0 68.2 461.3 473.8 90.0 56.8 29.8 147.9 89.7 94.2 51.1 56.1 122.6 107.1 82.5 21.6 582.1 234.8 130.2 126.3 293.3 189.8 102.9 595.6 349.6 217.5 75.1 209.0 206.6 146.2 101.7 341.4 65.9 463.5 32.4 36.7 58.0 39.0 47.7 38.7 22.4 30.7 34.6 38.0 20.8 24.6 22.4 29.2 23.2 48.2 17.5 24.6 39.1 30.9 29.8 28.9 32.0 28.0 33.2 36.2 32.6 36.4 32.7 39.5 30.4 86.0 28.9 23.6 7.5 14.1 35.7 54.5 76.5 40.9 5.1 24.0 30.6 2.2 20.0 19.1 5.5 6.2 25.7 13.1 44.1 7.9 29.0 0.7 14.7 58.8 88.0 12.6 16.0 5.4 28.0 58.0 36.3 26.0 26.9 17.7 16.8 77.8 44.5 23.3 25.2 3.7 24.5 34.6 22.3 25.1 2.7 23.0 19.5 17.8 2.8 14.5 8.7 11.3 4.5 2.1 34.0 27.6 34.6 29.1 53.5 34.4 9.6 13.0 7.4 19.7 22.7 35.7 3.8 4.9 26.9 36.4 60.9 16.2 24.5 22.4 50.0 SHE ENSG00000169291 "Src homology 2 domain containing E" Q5VZ18 1 154469772-154502412 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.9;Alveolar cells type 2: 23.4;Endothelial cells: 64.4;Hepatic stellate cells: 85.3;Kupffer cells: 26.7;Late spermatids: 23.0;Microglial cells: 26.2;Spermatocytes: 30.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 49.1;TIME: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037417 Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA037417: AB_10672384" "unprognostic (3.24e-1)" "unprognostic (4.95e-2)" "unprognostic (7.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (6.80e-3)" "unprognostic (7.24e-2)" "unprognostic (3.07e-3)" "unprognostic (3.10e-2)" "unprognostic (8.22e-2)" "unprognostic (4.04e-2)" "unprognostic (8.29e-2)" "unprognostic (2.40e-2)" "unprognostic (7.31e-2)" "unprognostic (1.62e-1)" "unprognostic (3.33e-3)" "unprognostic (1.33e-2)" 23.4 9.8 9.4 3.3 8.8 1.2 20.9 7.7 10.6 13.2 7.4 7.4 3.4 12.1 4.3 5.0 12.5 6.9 22.7 8.3 8.3 10.5 5.8 20.6 3.9 8.4 9.1 7.6 3.0 4.9 3.7 16.5 8.8 8.1 4.2 0.6 5.4 4.2 7.1 6.4 8.9 8.0 8.1 21.4 5.5 22.2 10.2 2.6 22.1 11.3 2.3 9.7 9.9 8.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 4.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 49.1 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.5 0.0 1.0 13.6 0.0 0.3 1.4 0.0 0.1 0.2 0.1 0.0 1.0 0.0 0.5 0.3 0.2 1.5 1.5 1.1 0.9 0.6 0.6 0.1 0.9 0.8 0.9 2.4 1.7 1.1 4.0 0.0 0.5 9.4 8.8 7.7 10.6 8.3 8.3 8.4 9.1 8.8 8.1 10.2 8.0 56.9 0.0 23.4 3.9 0.3 3.3 0.4 0.3 1.2 0.1 0.4 1.3 4.4 1.5 1.3 1.8 0.0 0.0 0.2 0.0 0.0 0.1 13.0 0.4 0.3 64.4 0.0 2.7 0.3 0.0 0.0 6.7 0.0 0.5 3.8 2.1 85.3 3.4 1.4 0.0 0.3 0.0 0.0 26.7 6.6 23.0 1.5 2.0 0.0 26.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 3.7 0.7 0.0 0.1 0.0 0.4 0.0 3.3 2.2 30.6 13.0 0.3 1.6 0.1 0.7 0.3 0.0 0.3 SHFL "C19orf66, FLJ11286, IRAV, RyDEN, SFL" ENSG00000130813 "Shiftless antiviral inhibitor of ribosomal frameshifting" Q9NUL5 19 10086122-10093252 "Predicted intracellular proteins" "Antiviral defense" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 75.7" "Cell type enhanced" "Detected in some" "Adipocytes: 23.3;dendritic cells: 21.7;Fibroblasts: 6.8;Hofbauer cells: 32.6;Plasma cells: 9.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 71.8;BJ hTERT+ SV40 Large T+ RasG12V: 81.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042001 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA042001: AB_10794167" "prognostic favorable (4.04e-4)" "unprognostic (1.21e-2)" "unprognostic (2.39e-3)" "unprognostic (2.03e-1)" "unprognostic (2.19e-2)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (6.57e-2)" "unprognostic (4.22e-3)" "unprognostic (2.34e-1)" "unprognostic (1.88e-1)" "prognostic unfavorable (8.96e-11)" "unprognostic (5.92e-2)" "unprognostic (1.81e-1)" "unprognostic (4.41e-3)" "prognostic favorable (1.35e-4)" 12.8 18.5 27.1 14.2 27.4 15.7 12.2 26.3 30.1 17.0 24.4 12.8 14.8 15.8 16.5 8.6 17.6 18.1 8.2 27.2 28.5 14.0 75.7 16.8 22.8 27.3 27.0 18.9 9.9 16.7 14.1 12.7 27.2 11.9 9.9 15.0 16.3 19.1 4.4 9.5 18.4 15.4 28.8 19.9 11.0 4.3 29.5 20.4 12.2 6.9 16.6 14.7 12.3 28.1 9.4 3.8 5.0 3.9 20.3 23.6 1.4 7.6 46.3 71.8 81.2 0.4 7.4 4.8 2.1 24.0 25.7 3.9 3.9 20.7 12.0 30.4 0.4 15.5 3.0 10.6 32.6 4.7 9.7 34.3 11.7 11.5 4.1 27.1 22.9 20.6 1.8 20.2 15.0 6.5 20.1 13.3 1.1 7.0 5.5 16.2 0.0 8.0 14.8 13.0 0.7 3.5 12.9 1.3 42.2 0.9 1.2 12.9 14.8 6.0 3.0 9.6 1.6 24.1 7.2 1.2 16.8 6.0 12.1 16.4 12.8 18.2 23.3 11.7 31.1 13.0 19.5 25.4 10.2 10.1 16.3 17.7 16.4 32.7 20.3 2.0 21.7 15.5 27.1 27.4 26.3 30.1 27.2 28.5 27.3 27.0 27.2 28.8 29.5 28.1 23.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 5.4 21.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 6.7 6.8 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 2.6 3.3 0.0 0.0 0.0 SHH "HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS" ENSG00000164690 "Sonic hedgehog signaling molecule" Q15465 7 155799980-155812463 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, Hydrolase, Protease" "Disease variant, Holoprosencephaly, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 13.6;stomach 1: 10.5;urinary bladder: 16.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 8.3;Cholangiocytes: 18.6;Collecting duct cells: 9.2;Gastric mucus-secreting cells: 9.7;Hepatocytes: 20.1;Intestinal goblet cells: 8.6;Pancreatic endocrine cells: 11.7;Urothelial cells: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 8.9;GAMG: 39.8;OE19: 10.2;RT4: 25.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 5500000 "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (7.17e-2)" "unprognostic (7.68e-3)" "unprognostic (6.70e-2)" "prognostic favorable (8.62e-5)" "unprognostic (1.59e-1)" "unprognostic (2.50e-2)" "unprognostic (2.39e-3)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.16e-2)" "unprognostic (3.47e-1)" "unprognostic (1.56e-1)" "unprognostic (1.77e-3)" "unprognostic (2.86e-1)" "unprognostic (2.85e-1)" "unprognostic (3.43e-2)" "unprognostic (2.66e-2)" 0.0 8.7 1.3 0.3 1.2 0.0 0.0 1.6 1.2 4.4 0.3 1.3 1.4 0.4 3.0 0.0 0.1 3.8 0.0 0.8 6.2 3.3 13.6 1.7 0.0 3.3 1.6 0.0 0.2 0.0 0.1 0.0 4.6 1.2 1.0 0.3 0.0 1.2 0.0 0.1 1.4 0.0 1.0 0.0 10.5 0.1 2.6 0.0 0.0 0.0 0.0 16.2 0.3 1.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.2 0.0 8.9 0.0 39.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 10.2 4.0 0.0 0.0 0.0 2.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.3 1.2 1.6 1.2 0.8 6.2 3.3 1.6 4.6 1.0 2.6 1.6 0.0 3.2 7.8 0.0 0.0 0.0 8.3 0.0 0.0 1.5 0.0 0.0 0.7 18.6 1.3 9.2 0.0 0.0 0.0 3.7 0.0 1.2 4.7 5.4 0.5 0.2 0.0 0.0 0.1 0.8 0.2 0.1 9.7 7.6 0.0 0.0 0.4 20.1 0.0 0.0 0.4 8.6 0.0 0.6 0.0 1.7 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.7 0.5 0.4 0.1 1.3 2.5 6.6 0.0 0.1 0.0 0.0 0.1 2.7 0.2 0.0 0.0 0.0 0.0 0.0 3.0 8.3 SHISA5 "hShisa5, SCOTIN" ENSG00000164054 "Shisa family member 5" Q8N114 3 48467798-48504826 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 279.7;Extravillous trophoblasts: 229.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042295 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA042295: AB_10794794" "unprognostic (3.52e-3)" "unprognostic (4.79e-2)" "unprognostic (1.71e-1)" "unprognostic (3.98e-2)" "unprognostic (8.58e-3)" "unprognostic (2.48e-1)" "prognostic unfavorable (3.72e-6)" "unprognostic (3.82e-3)" "unprognostic (8.76e-3)" "unprognostic (1.21e-3)" "unprognostic (1.39e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (8.64e-5)" "unprognostic (1.11e-1)" "unprognostic (6.08e-3)" "unprognostic (3.81e-3)" "unprognostic (1.74e-2)" 97.5 71.8 74.2 68.3 71.9 65.0 82.2 58.8 92.2 99.6 113.0 82.1 60.6 91.4 45.3 140.6 94.9 70.6 75.0 72.3 88.9 94.3 115.0 101.7 80.1 76.8 73.6 86.3 58.3 48.0 70.2 138.4 72.0 107.9 39.5 13.7 69.1 69.8 22.8 60.1 74.5 67.1 70.8 114.3 73.5 35.5 87.6 84.4 76.8 31.7 66.9 116.8 98.3 65.2 71.0 141.9 82.4 132.0 153.1 194.7 417.7 115.3 209.0 254.3 187.9 157.4 175.6 97.7 123.2 200.9 240.9 91.7 91.5 148.3 70.7 116.4 63.6 89.2 91.2 128.2 256.7 61.9 164.0 200.9 169.3 205.7 141.7 141.7 193.2 129.0 56.6 115.6 138.2 154.1 70.4 111.1 150.4 101.2 113.0 48.2 36.7 133.4 130.5 446.6 24.6 13.8 74.9 79.1 155.6 136.8 91.5 91.2 153.6 90.5 100.8 155.2 112.0 87.0 76.3 85.8 128.2 118.3 90.2 205.9 301.6 252.5 320.7 267.5 283.4 165.0 264.1 293.8 167.3 222.6 210.9 219.4 910.2 138.7 306.9 126.7 345.7 500.0 74.2 71.9 58.8 92.2 72.3 88.9 76.8 73.6 72.0 70.8 87.6 65.2 69.8 41.7 39.4 12.1 55.8 27.8 73.0 52.2 114.4 22.7 29.6 29.8 17.3 51.5 37.6 64.4 16.7 279.7 56.3 43.0 11.7 79.4 4.2 29.2 49.8 79.4 37.8 22.9 10.8 104.3 229.9 57.4 36.2 31.2 34.8 41.5 66.0 88.0 103.0 6.7 11.0 48.3 14.2 57.5 27.3 5.7 49.0 47.7 46.2 18.7 46.5 30.1 101.0 10.6 10.4 80.2 31.2 39.1 54.5 50.2 64.9 43.3 38.0 5.0 32.9 22.1 43.9 5.1 8.8 85.9 32.1 120.5 74.0 49.9 40.3 50.5 SHKBP1 "PP203, Sb1" ENSG00000160410 "SH3KBP1 binding protein 1" Q8TBC3 19 40576853-40591399 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041887 Uncertain Approved "Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Cell Junctions" "HPA041887: AB_10794639" "unprognostic (1.26e-1)" "unprognostic (7.55e-2)" "unprognostic (1.38e-1)" "unprognostic (4.52e-2)" "unprognostic (8.24e-2)" "unprognostic (9.14e-2)" "unprognostic (1.66e-3)" "unprognostic (3.53e-2)" "unprognostic (6.98e-2)" "unprognostic (6.69e-3)" "unprognostic (1.42e-1)" "unprognostic (6.87e-2)" "unprognostic (5.29e-2)" "unprognostic (6.15e-2)" "unprognostic (2.67e-1)" "unprognostic (1.65e-1)" "unprognostic (8.64e-2)" 33.7 32.1 14.6 39.4 16.5 66.8 29.1 15.3 19.4 35.3 15.4 34.9 18.4 34.4 7.7 47.0 33.3 14.4 29.6 14.8 16.1 42.3 30.0 52.3 40.9 19.7 16.6 25.2 37.6 15.8 21.8 14.3 17.2 35.1 10.4 1.3 31.7 13.5 15.8 32.6 45.5 15.8 15.6 127.1 41.2 17.2 19.4 29.5 35.0 6.8 25.0 36.5 35.6 20.0 70.9 107.1 21.1 30.2 18.0 20.0 39.7 26.8 39.9 41.1 56.2 46.9 47.5 73.9 52.1 42.3 35.0 30.2 27.3 50.8 19.4 114.6 65.1 53.9 29.4 32.1 38.8 50.6 147.9 32.4 36.2 37.4 23.3 30.0 60.8 81.7 30.7 60.2 32.0 61.6 52.1 70.5 15.3 63.5 39.2 92.9 27.4 55.7 34.0 57.0 17.4 40.2 41.4 22.3 25.1 20.2 35.5 82.7 46.4 41.2 54.0 65.1 54.1 56.4 28.4 50.6 66.2 59.5 37.4 223.9 217.9 216.7 74.2 202.2 60.1 77.5 71.4 76.5 157.3 69.0 41.1 48.2 453.9 72.3 246.4 46.4 109.8 213.1 14.6 16.5 15.3 19.4 14.8 16.1 19.7 16.6 17.2 15.6 19.4 20.0 28.8 12.8 19.9 1.3 53.1 8.5 20.5 41.7 10.2 2.1 9.5 7.2 4.3 17.2 30.8 29.5 6.2 24.5 40.8 35.2 29.4 42.5 8.6 5.4 9.3 25.0 22.8 25.0 2.1 38.6 53.1 13.5 37.2 13.3 51.5 18.2 26.7 13.2 76.5 3.3 1.8 17.9 48.8 82.0 36.3 18.4 14.6 66.8 23.2 3.7 93.3 6.3 56.7 1.5 6.4 39.0 35.9 12.4 33.9 11.5 28.1 31.7 14.2 1.8 0.0 7.0 15.2 3.5 26.8 19.3 9.8 29.6 45.0 14.4 22.0 20.7 SHROOM3 "APXL3, KIAA1481, SHRM, ShrmL" ENSG00000138771 "Shroom family member 3" Q8TF72 4 76435229-76783253 "Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 313.1;Distal enterocytes: 154.5;Endometrial ciliated cells: 182.9;Glandular and luminal cells: 350.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 40.8;AF22: 38.2;BJ hTERT+: 36.9;EFO-21: 39.9;OE19: 40.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047784 Enhanced NA NA "Cluster 37: Intestine - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA047784: AB_2680155" "unprognostic (1.96e-1)" "unprognostic (2.50e-1)" "unprognostic (1.57e-2)" "unprognostic (5.33e-2)" "unprognostic (1.61e-2)" "unprognostic (3.33e-2)" "unprognostic (7.96e-3)" "unprognostic (2.70e-2)" "unprognostic (1.92e-1)" "unprognostic (2.90e-1)" "unprognostic (1.45e-3)" "unprognostic (1.03e-1)" "prognostic favorable (1.64e-13)" "unprognostic (2.87e-2)" "unprognostic (2.25e-1)" "unprognostic (9.06e-2)" "unprognostic (1.87e-2)" 1.0 2.0 0.4 6.1 1.8 0.1 15.4 12.4 3.4 5.9 18.5 20.0 15.2 3.0 13.9 17.5 15.7 17.8 3.9 0.9 0.0 7.0 6.2 8.5 0.4 6.1 2.1 0.5 6.5 12.9 3.3 4.4 5.9 9.0 17.2 9.7 25.7 6.3 0.1 3.0 14.7 9.7 5.6 6.1 21.9 0.7 0.2 0.9 3.5 0.1 2.4 4.9 2.3 3.0 40.8 7.9 38.2 25.2 0.0 0.6 1.4 12.4 36.9 0.8 1.6 6.8 26.3 0.6 39.9 34.6 3.0 20.4 5.1 17.8 0.7 0.1 6.7 0.0 7.5 0.0 0.2 0.0 0.0 0.3 4.3 1.3 6.7 9.7 0.7 0.3 0.0 9.7 0.8 3.6 0.7 0.1 16.0 40.5 4.7 3.5 6.3 6.3 6.0 0.9 15.0 19.9 5.2 28.2 2.1 23.2 6.8 0.2 0.0 6.5 5.5 0.2 5.4 12.0 13.3 0.1 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.8 12.4 3.4 0.9 0.0 6.1 2.1 5.9 5.6 0.2 3.0 0.6 89.8 53.4 313.1 1.0 0.9 5.8 14.0 2.8 35.8 69.9 46.1 11.0 81.5 40.0 35.0 75.0 0.4 0.6 154.5 0.0 33.6 7.1 182.9 27.1 2.1 86.9 2.7 54.5 36.4 0.7 4.7 103.0 350.1 0.0 11.9 0.7 42.2 0.2 1.7 19.1 104.0 30.5 1.6 0.3 3.2 0.3 1.8 3.6 29.0 1.6 7.2 0.0 6.0 2.1 73.8 92.3 0.0 0.3 35.8 102.7 6.8 65.7 31.1 0.0 0.3 7.4 3.4 2.4 3.5 0.3 0.1 1.7 0.3 70.5 11.9 SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 104.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 58.0;Cardiomyocytes: 59.5;Distal enterocytes: 102.4;Paneth cells: 53.0;Proximal enterocytes: 51.6;Undifferentiated cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 88.6;ASC TERT1: 91.3;HSkMC: 98.9;OE19: 97.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" NA NA 2200000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favorable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favorable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" 18.7 17.3 16.8 11.8 21.6 3.7 15.9 26.9 19.8 13.0 38.9 97.8 34.3 7.1 34.3 13.6 19.3 16.7 43.8 16.1 27.1 62.1 43.4 20.6 5.8 25.3 23.7 5.7 17.3 45.3 14.4 11.8 24.7 20.4 104.4 6.2 18.4 15.3 26.7 13.0 35.8 10.4 23.0 9.1 19.0 10.3 24.9 3.7 54.0 33.3 6.7 16.8 7.8 26.3 8.9 14.0 8.0 34.6 88.6 91.3 20.9 16.8 24.0 4.3 2.6 10.9 61.4 5.5 24.2 21.5 9.4 17.3 12.8 18.7 4.2 26.0 3.9 8.6 3.7 11.1 41.8 0.7 7.2 98.9 24.9 11.4 17.3 58.5 30.6 11.0 7.1 37.5 14.8 16.5 0.2 0.6 5.0 97.7 28.5 3.2 0.2 8.4 51.4 12.1 2.4 5.1 46.5 18.6 8.0 24.0 36.8 3.2 34.1 23.6 4.3 26.5 4.0 9.4 7.5 0.7 8.3 4.6 9.8 7.6 2.9 0.1 0.4 2.1 0.3 0.5 1.3 0.6 1.9 0.7 1.7 1.1 0.5 0.2 3.7 0.5 0.6 1.8 16.8 21.6 26.9 19.8 16.1 27.1 25.3 23.7 24.7 23.0 24.9 26.3 4.2 19.2 58.0 11.8 2.4 3.2 6.3 6.7 7.4 6.5 10.1 4.3 59.5 12.8 9.4 36.8 0.0 7.6 0.6 102.4 9.8 15.2 14.0 9.1 9.3 6.9 14.5 5.2 15.0 3.8 8.8 7.5 12.8 14.0 1.3 3.9 8.9 30.0 4.5 5.0 9.1 31.0 4.1 3.5 1.6 12.0 3.1 4.3 3.6 6.5 4.5 1.9 1.0 8.0 6.7 5.2 53.0 1.2 3.9 7.4 51.6 26.2 11.9 1.8 0.0 4.9 7.9 14.8 9.6 12.2 5.3 6.7 2.0 8.9 63.6 7.1 SIDT2 CGI-40 ENSG00000149577 "SID1 transmembrane family member 2" Q8NBJ9 11 117178736-117197445 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 83.5;non-classical monocyte: 151.0" "Lineage enriched" "Detected in all" 7 "monocytes: 151.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052352 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "HPA052352: AB_2681797" "unprognostic (3.83e-1)" "unprognostic (4.30e-2)" "unprognostic (9.92e-2)" "unprognostic (1.03e-1)" "unprognostic (3.01e-2)" "unprognostic (1.69e-1)" "unprognostic (3.34e-1)" "unprognostic (1.84e-1)" "unprognostic (1.39e-1)" "unprognostic (3.12e-1)" "unprognostic (2.67e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (4.18e-5)" "unprognostic (2.74e-2)" "unprognostic (2.20e-1)" "unprognostic (4.36e-2)" "unprognostic (5.22e-3)" 40.2 25.1 23.5 21.2 28.4 12.4 36.3 27.4 27.1 32.8 19.4 28.8 44.2 30.5 16.0 15.1 31.3 18.5 31.8 24.1 23.2 20.6 40.8 36.4 23.4 37.0 29.2 60.2 113.4 13.6 35.7 22.4 33.9 48.6 23.1 14.4 31.5 21.2 25.2 32.7 42.3 20.8 29.7 34.6 75.9 28.5 29.2 10.0 31.7 12.3 20.4 26.2 20.4 48.9 8.7 8.8 10.5 15.4 34.4 30.7 34.8 14.8 19.5 9.3 8.6 25.1 32.8 8.9 23.1 39.1 11.7 9.0 10.2 11.5 7.6 13.2 12.4 6.3 15.8 17.3 17.8 5.3 15.5 38.1 12.8 12.0 12.9 28.6 19.1 11.4 12.0 19.2 22.1 18.2 7.5 6.2 4.9 45.6 6.5 5.6 7.2 25.5 12.2 9.1 3.2 7.9 15.8 38.1 2.6 11.7 30.8 6.3 11.9 12.3 7.9 8.2 3.4 13.6 5.3 9.4 7.1 10.8 9.2 0.3 14.2 0.5 1.9 83.5 1.5 18.3 1.1 1.3 11.5 21.2 1.7 1.3 1.7 1.5 151.0 6.2 1.4 9.6 23.5 28.4 27.4 27.1 24.1 23.2 37.0 29.2 33.9 29.7 29.2 48.9 12.2 6.4 12.3 11.8 24.1 67.7 25.4 4.1 4.0 13.0 11.1 13.0 7.9 4.3 4.5 11.0 6.2 9.2 6.7 16.7 0.0 4.4 7.4 11.6 22.2 12.7 11.4 8.2 7.7 9.6 33.4 19.7 61.2 11.2 2.5 43.5 16.4 25.6 16.9 18.5 8.8 32.9 2.0 54.2 29.3 11.5 13.4 30.6 19.6 7.5 13.6 6.1 7.2 12.1 16.8 8.0 9.4 13.5 6.6 20.5 40.7 1.8 6.0 12.1 19.7 46.1 18.7 5.8 4.8 4.2 42.9 32.3 9.5 38.2 13.5 15.5 SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in some" "B-cells: 33.0;granulocytes: 39.3;Kupffer cells: 93.9;Macrophages: 51.5" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 765.3;intermediate monocyte: 252.0;non-classical monocyte: 539.2" "Group enriched" "Detected in many" 16 "granulocytes: 765.3;monocytes: 539.2" "Cell line enhanced" "Detected in some" "Daudi: 28.8;HDLM-2: 9.0;HEL: 14.9;HMC-1: 10.7;NB-4: 10.4;U-698: 21.3;U-937: 12.0" "Not detected" "Not detected" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" 3.5 6.4 3.9 33.9 4.8 14.9 2.1 4.3 6.0 2.1 3.5 5.4 7.0 2.1 1.0 2.0 2.4 3.7 1.4 3.9 6.2 1.7 3.2 8.5 19.9 11.4 6.9 1.6 3.5 1.0 1.4 1.8 8.8 3.0 4.6 1.1 2.2 1.1 0.7 1.2 12.2 4.5 6.3 38.5 4.7 1.3 6.3 4.0 1.0 1.1 19.5 5.5 1.2 9.4 0.2 0.0 0.5 0.5 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 1.3 28.8 0.9 0.1 0.3 0.5 0.0 0.2 0.0 9.0 2.5 14.9 0.3 0.1 0.0 6.4 10.7 0.1 0.0 0.1 0.0 0.1 0.0 1.7 0.7 1.4 0.0 0.6 0.2 10.4 0.8 0.7 0.4 1.9 0.1 0.5 0.0 0.3 0.4 0.4 0.3 0.1 0.2 0.5 0.1 5.2 0.7 0.7 1.3 0.6 0.2 1.3 0.3 21.3 0.5 12.0 0.5 14.0 41.9 765.3 0.8 252.0 0.4 41.4 0.5 0.5 38.0 27.4 0.3 0.5 87.2 0.4 539.2 2.2 1.1 40.7 3.9 4.8 4.3 6.0 3.9 6.2 11.4 6.9 8.8 6.3 6.3 9.4 0.7 3.2 1.3 0.3 33.0 0.1 1.2 0.0 0.0 1.4 0.4 0.9 0.3 0.0 0.0 1.8 2.1 0.1 0.6 0.1 0.0 0.0 0.9 0.0 0.0 4.2 0.0 5.2 0.6 0.0 0.1 0.8 0.0 0.1 39.3 0.1 0.4 1.0 8.1 0.0 0.2 0.1 0.0 93.9 6.3 0.4 0.0 51.5 0.0 15.0 14.8 0.2 6.2 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.7 0.0 2.0 0.4 0.5 0.7 0.0 1.3 0.1 2.7 0.1 0.0 0.9 SIGLEC6 "CD327, CD33L, CD33L1, OB-BP1, SIGLEC-6" ENSG00000105492 "Sialic acid binding Ig like lectin 6" O43699 19 51517819-51531856 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "placenta: 106.7" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 76.0;granulocytes: 55.0;Syncytiotrophoblasts: 188.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 4.9;memory B-cell: 7.2;naive B-cell: 4.5;plasmacytoid DC: 11.0" "Group enriched" "Detected in many" 13 "B-cells: 7.2;dendritic cells: 11.0;granulocytes: 4.9" "Cell line enriched" "Detected in some" 7 "HMC-1: 500.7" "HPA008945, HPA009084, HPA018198" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA008945: , HPA009084: AB_1079967, HPA018198: AB_1856868" "unprognostic (1.97e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (9.31e-3)" "unprognostic (8.46e-4)" "unprognostic (2.91e-1)" "unprognostic (2.02e-2)" "unprognostic (2.64e-1)" "unprognostic (8.96e-2)" "unprognostic (2.03e-1)" "unprognostic (6.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.15e-2)" "unprognostic (4.42e-2)" "unprognostic (3.28e-2)" "unprognostic (5.57e-3)" 0.6 0.1 0.2 3.0 0.3 0.5 0.7 0.4 0.3 1.6 0.1 2.2 2.2 1.5 1.0 2.5 0.3 2.5 0.4 0.2 0.0 0.1 0.1 4.3 3.8 0.1 0.1 0.1 0.3 0.1 0.0 106.7 0.2 1.0 3.1 0.4 0.5 0.7 0.5 0.5 3.3 1.3 0.0 1.7 2.6 0.3 0.2 0.7 0.0 0.6 4.2 1.8 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 15.8 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 73.1 0.0 0.0 0.0 1.2 500.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.3 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 19.1 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.9 0.2 4.9 0.1 0.0 0.0 0.0 0.0 7.2 0.0 0.0 1.6 4.5 0.0 0.0 0.2 0.6 0.0 11.0 0.0 0.4 0.2 0.3 0.4 0.3 0.2 0.0 0.1 0.1 0.2 0.0 0.2 0.5 0.0 0.0 1.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 5.2 0.7 0.0 0.0 55.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 188.7 0.5 0.0 0.0 0.0 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIGLECL1 "C19orf75, FLJ40235, SIGLEC23P, SIGLECP7" ENSG00000179213 "SIGLEC family like 1" Q8N7X8 19 51246348-51269330 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 73 "testis: 22.5" "Group enriched" "Detected in some" 8 "Early spermatids: 46.6;Late spermatids: 65.9;Spermatocytes: 73.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA079471 Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA079471: " "unprognostic (5.41e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 65.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.5 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SIGMAR1 "OPRS1, SR-BP1" ENSG00000147955 "Sigma non-opioid intracellular receptor 1" Q99720 9 34634722-34637844 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Receptor "Amyotrophic lateral sclerosis, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 187.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 98.7;Hepatocytes: 97.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013470, HPA018002, HPA024071" Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 33: Fibroblasts - ECM organization" "CAB013470: AB_2533521, HPA018002: AB_1854802, HPA024071: AB_1854803" "unprognostic (1.39e-1)" "unprognostic (2.64e-1)" "unprognostic (1.56e-1)" "unprognostic (1.95e-1)" "unprognostic (8.06e-2)" "unprognostic (3.71e-2)" "unprognostic (4.89e-2)" "unprognostic (2.50e-2)" "unprognostic (2.58e-2)" "unprognostic (2.01e-3)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (2.78e-2)" "unprognostic (2.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.44e-3)" "prognostic unfavorable (3.42e-4)" 42.0 52.4 25.2 19.4 25.3 20.5 38.1 26.2 27.1 53.0 27.4 42.0 46.0 50.7 45.0 54.1 46.9 22.1 34.0 25.8 30.2 25.5 187.6 27.5 16.9 28.3 28.7 46.1 45.7 39.0 22.0 27.6 29.4 35.5 31.2 7.2 35.0 38.5 17.6 53.9 40.0 34.8 26.2 24.2 42.1 20.2 33.3 19.1 29.7 13.5 22.2 46.3 43.5 27.1 184.3 162.6 59.8 175.3 205.7 138.7 66.5 127.1 91.2 115.8 105.9 97.6 76.8 87.8 71.9 151.7 69.8 108.8 94.5 151.3 57.8 144.7 175.6 78.0 225.0 112.7 131.7 145.0 67.6 142.9 163.0 131.2 197.7 59.4 90.2 114.5 30.1 156.2 139.7 1.8 88.2 215.2 68.8 101.5 184.4 101.4 59.6 258.3 111.0 36.5 57.6 65.5 123.3 89.5 70.0 32.0 106.9 98.7 68.5 90.0 69.9 96.4 19.2 43.2 71.6 2.5 97.2 123.9 191.8 24.3 39.5 24.2 43.0 39.3 46.2 26.5 62.5 51.3 48.9 21.1 51.7 43.6 10.7 28.7 42.5 35.1 65.5 43.5 25.2 25.3 26.2 27.1 25.8 30.2 28.3 28.7 29.4 26.2 33.3 27.1 11.0 3.2 13.6 6.8 12.3 18.4 16.8 24.6 14.2 10.1 26.8 18.9 9.2 15.7 12.1 7.3 0.0 44.8 10.7 33.0 0.0 33.0 0.9 7.0 23.7 14.4 10.3 23.5 5.6 33.5 98.7 29.2 18.3 10.1 7.0 19.4 13.9 97.5 38.8 5.0 6.4 28.2 12.2 10.5 7.8 1.8 27.4 10.8 19.6 5.6 9.5 13.8 14.4 5.0 4.4 32.1 31.5 25.6 22.4 25.9 58.4 13.7 6.8 7.7 19.7 12.1 23.9 6.0 10.3 40.0 21.5 36.5 13.6 26.2 47.3 16.1 SIL1 "BAP, MSS, ULG5" ENSG00000120725 "SIL1 nucleotide exchange factor" Q9H173 5 138946724-139293557 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011949 Enhanced "Intracellular and membrane" NA NA 710000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "HPA011949: AB_1856875" "unprognostic (1.06e-1)" "unprognostic (9.01e-2)" "unprognostic (2.04e-1)" "prognostic favorable (4.34e-4)" "prognostic unfavorable (4.27e-4)" "unprognostic (9.12e-3)" "unprognostic (3.60e-1)" "unprognostic (2.45e-1)" "unprognostic (1.33e-1)" "unprognostic (6.91e-2)" "unprognostic (2.31e-2)" "unprognostic (9.46e-2)" "unprognostic (3.21e-3)" "unprognostic (1.59e-1)" "unprognostic (1.65e-1)" "unprognostic (6.79e-2)" "unprognostic (1.22e-2)" 26.4 46.4 9.0 19.7 10.6 24.1 21.6 8.5 11.8 21.7 17.9 20.0 24.6 21.7 32.5 16.5 19.2 23.2 29.5 9.2 9.3 20.9 54.9 22.6 14.1 10.6 9.9 19.1 67.7 33.7 28.5 28.7 10.5 23.9 12.8 5.7 36.7 25.8 41.4 23.2 16.4 17.2 8.2 17.3 29.5 49.8 11.3 9.0 36.2 18.0 10.0 20.6 16.2 10.3 33.7 34.9 11.3 56.2 84.0 48.3 65.0 54.0 58.2 26.6 57.3 36.9 78.9 12.4 89.7 74.2 32.2 29.8 12.0 76.0 15.8 33.7 20.7 16.4 23.9 40.9 67.2 4.9 72.6 60.7 73.1 46.4 79.0 42.7 40.5 15.4 8.7 131.3 32.2 52.1 12.4 15.1 2.4 38.6 4.2 8.9 7.8 92.7 38.9 17.7 19.5 13.0 46.3 44.3 74.5 24.8 38.4 30.6 30.6 46.8 10.9 17.9 23.6 56.3 31.6 8.2 34.3 38.1 39.9 18.1 47.7 19.4 17.4 52.4 10.9 20.1 12.1 16.8 51.3 14.7 12.1 15.1 5.7 22.1 42.3 37.3 11.7 27.1 9.0 10.6 8.5 11.8 9.2 9.3 10.6 9.9 10.5 8.2 11.3 10.3 22.5 19.2 47.0 51.6 32.5 22.0 33.4 61.6 15.4 9.0 33.8 21.6 30.3 38.6 48.1 42.3 37.5 121.2 19.0 41.5 11.7 61.8 109.1 25.5 37.0 21.9 33.5 7.6 75.7 81.7 104.2 46.3 38.7 32.1 60.3 29.2 29.3 143.8 70.3 25.2 73.7 64.3 52.9 33.9 21.0 195.7 28.6 36.7 48.0 49.6 113.8 15.2 17.5 66.4 57.6 46.2 34.9 22.2 114.5 32.1 51.1 46.5 51.6 26.6 19.7 21.4 27.7 96.9 61.8 13.0 23.9 153.6 16.9 60.3 43.0 30.1 SIRPB1 "CD172b, SIRP-BETA-1" ENSG00000101307 "Signal regulatory protein beta 1" "O00241, Q5TFQ8" 20 1561385-1620061 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.2;lung: 19.4;lymphoid tissue: 28.6" "Cell type enhanced" "Detected in some" "dendritic cells: 10.9;Hofbauer cells: 14.7;Kupffer cells: 29.4;Macrophages: 30.9;monocytes: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 1594.8" "Group enriched" "Detected in all" 6 "granulocytes: 1594.8;monocytes: 502.2" "Group enriched" "Detected in some" 4 "HMC-1: 54.0;NB-4: 76.2;THP-1: 58.9" HPA047463 Uncertain Uncertain Vesicles,Centrosome NA NA 44000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles Centrosome "HPA047463: AB_2680057" "unprognostic (1.88e-2)" "unprognostic (6.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (5.38e-2)" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (7.18e-2)" "unprognostic (4.11e-3)" "unprognostic (9.12e-2)" "unprognostic (6.31e-2)" "unprognostic (4.57e-2)" "unprognostic (2.65e-3)" "unprognostic (5.76e-2)" "unprognostic (2.39e-3)" "unprognostic (5.00e-3)" "unprognostic (1.19e-2)" 5.4 1.6 1.3 28.6 1.3 52.2 1.9 1.2 4.2 1.2 0.1 2.1 1.5 0.8 0.8 1.3 2.2 11.2 1.6 1.4 0.8 1.2 3.1 19.4 11.0 0.7 0.8 0.7 1.3 0.3 0.6 2.8 1.3 0.8 1.8 1.2 1.7 0.9 0.8 0.8 2.8 3.2 0.9 24.5 1.5 0.6 2.1 4.5 0.9 1.5 4.3 8.1 0.8 1.9 0.2 0.0 0.2 0.1 0.3 0.5 0.2 0.4 0.1 0.2 0.0 0.2 0.1 0.1 0.8 0.4 7.1 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.2 14.9 54.0 0.1 0.2 0.3 0.0 8.0 0.5 1.1 0.0 0.2 0.4 0.1 0.0 76.2 0.2 0.0 3.3 0.2 0.0 0.1 10.8 0.3 0.1 0.2 0.2 0.0 0.5 0.0 0.0 58.9 1.6 0.7 0.1 0.4 0.3 0.1 0.1 0.1 1.1 13.4 0.2 6.1 502.2 868.9 7.3 419.7 10.3 2.8 6.5 5.7 175.2 3.4 8.8 5.5 1594.8 8.2 357.6 165.7 11.8 287.0 1.3 1.3 1.2 4.2 1.4 0.8 0.7 0.8 1.3 0.9 2.1 1.9 0.6 3.2 5.2 0.3 1.2 0.0 0.1 0.2 0.6 0.2 0.1 0.0 0.5 0.0 1.6 0.0 0.0 0.2 10.9 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 1.3 0.3 0.0 0.1 0.7 0.0 0.2 7.0 0.0 1.8 0.2 14.7 0.0 0.1 0.0 0.0 29.4 0.0 0.0 0.0 30.9 0.0 0.0 26.7 0.1 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 SIRPD "dJ576H24.4, PTPNS1L2" ENSG00000125900 "Signal regulatory protein delta" Q9H106 20 1534251-1557705 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 57.8" "Group enriched" "Detected in some" 118 "Early spermatids: 427.6;Late spermatids: 522.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "neutrophil: 37.2" "Group enriched" "Detected in many" 4 "granulocytes: 37.2;monocytes: 21.0" "Cell line enhanced" "Detected in some" "HL-60: 1.5;HMC-1: 1.9;NB-4: 2.6;THP-1: 5.6;U-937: 1.2" "Not detected" "Not detected" HPA042663 Enhanced "Secreted in male reproductive system" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 36: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "HPA042663: AB_2678102" "unprognostic (4.91e-2)" "unprognostic (1.51e-2)" "unprognostic (3.01e-2)" "unprognostic (4.47e-1)" "unprognostic (2.49e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-2)" "unprognostic (2.79e-1)" "unprognostic (3.66e-8)" "unprognostic (2.14e-1)" "unprognostic (3.32e-2)" "unprognostic (9.57e-3)" "unprognostic (2.44e-2)" 0.2 0.1 0.2 2.8 0.1 2.7 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.4 0.1 0.1 0.1 0.1 0.2 1.9 1.1 0.3 0.2 0.3 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.4 0.1 1.5 0.1 57.8 0.1 0.0 0.0 0.0 0.5 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.9 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 21.0 21.5 0.1 13.5 0.2 0.1 0.1 0.2 6.8 0.0 0.1 0.0 37.2 0.0 6.1 4.3 0.3 6.6 0.2 0.1 0.0 0.3 0.1 0.1 0.3 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 427.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 4.0 0.0 522.7 3.4 2.2 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SIRT1 SIR2L1 ENSG00000096717 "Sirtuin 1" Q96EB6 10 67884656-67918390 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Differentiation, Host-virus interaction, Myogenesis, Transcription, Transcription regulation" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Early spermatids: 292.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003855, HPA006295, HPA052351" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Mitochondria,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli fibrillar center, Mitochondria, Cytosol" "CAB003855: AB_365497, HPA006295: AB_1079975, HPA052351: AB_2681796" "unprognostic (1.55e-1)" "unprognostic (2.78e-1)" "unprognostic (9.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-2)" "unprognostic (2.48e-1)" "unprognostic (4.95e-2)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (2.18e-2)" "unprognostic (2.83e-2)" "unprognostic (9.67e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" 16.4 30.2 8.9 11.0 10.4 19.8 17.5 15.6 11.9 17.1 7.8 12.5 9.2 18.5 11.9 10.9 11.9 14.0 10.6 8.5 9.9 13.4 17.3 12.6 17.7 9.3 9.2 25.1 12.1 14.0 6.9 12.7 10.0 14.0 12.0 13.5 9.9 11.2 14.6 9.6 9.7 13.7 8.8 14.3 10.3 26.8 9.4 19.2 14.7 18.5 15.1 15.5 9.5 12.9 15.1 16.8 26.2 29.4 24.4 18.7 16.3 20.4 21.0 27.4 24.3 18.7 12.6 31.4 10.8 13.7 17.1 11.7 32.8 6.9 29.3 16.9 19.0 16.7 12.1 14.7 22.3 18.1 12.3 17.3 16.2 16.6 28.3 29.4 11.2 17.6 21.6 16.7 20.3 12.1 17.0 25.0 32.5 9.6 26.6 30.3 20.6 12.4 13.1 9.1 16.8 23.0 37.4 24.4 26.8 22.5 17.7 16.6 9.4 21.2 19.8 19.0 20.1 13.9 17.7 61.8 10.9 27.2 8.9 1.3 0.8 1.1 1.1 1.0 1.6 1.8 1.2 1.5 1.3 1.0 2.2 1.3 1.0 1.2 1.3 1.2 1.0 0.6 8.9 10.4 15.6 11.9 8.5 9.9 9.3 9.2 10.0 8.8 9.4 12.9 35.7 19.2 7.4 17.0 27.6 39.1 20.9 7.2 22.8 12.5 48.3 33.4 34.8 11.5 8.7 5.5 27.1 7.1 42.5 31.2 5.9 4.3 292.2 38.4 26.2 20.6 42.9 10.3 16.0 5.6 5.4 28.0 23.4 57.1 12.0 14.8 15.4 15.8 9.1 11.8 18.4 21.0 10.2 23.4 28.7 45.6 17.7 34.1 16.0 30.9 14.8 7.1 9.2 18.6 30.7 6.2 20.6 19.5 15.8 26.0 11.2 8.4 4.1 14.0 0.0 43.4 28.8 24.2 16.3 21.1 47.5 12.4 29.1 8.9 18.7 17.2 SIRT5 ENSG00000124523 "Sirtuin 5" Q9NXA8 6 13574227-13615158 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 52.5;Distal tubular cells: 52.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021798, HPA022002, HPA022992" Approved Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA021798: AB_1856911, HPA022002: AB_1856913, HPA022992: AB_1856915" "unprognostic (8.53e-2)" "unprognostic (7.79e-2)" "unprognostic (4.71e-2)" "unprognostic (5.26e-3)" "unprognostic (6.19e-2)" "unprognostic (1.63e-1)" "unprognostic (8.72e-2)" "unprognostic (1.38e-1)" "unprognostic (8.54e-3)" "unprognostic (2.77e-3)" "unprognostic (1.02e-1)" "unprognostic (1.65e-1)" "prognostic favorable (8.76e-10)" "unprognostic (2.39e-1)" "unprognostic (6.88e-2)" "unprognostic (6.86e-2)" "unprognostic (2.36e-3)" 7.2 6.0 9.4 5.2 10.6 5.8 6.6 10.4 12.2 5.4 13.5 8.1 7.7 6.1 5.6 5.6 9.2 5.2 28.6 10.5 10.6 11.5 33.5 5.4 8.3 9.2 9.6 10.1 6.7 16.2 7.3 5.6 9.9 6.4 8.7 6.1 10.6 6.8 33.4 7.9 9.8 5.9 8.4 9.6 8.2 6.8 10.9 8.2 9.0 38.0 7.2 6.0 5.4 11.1 10.5 8.9 8.1 10.4 5.7 8.9 7.6 5.1 5.3 6.1 8.0 12.9 11.1 14.1 35.7 4.3 10.9 16.9 7.4 11.1 7.6 5.9 10.3 8.5 5.6 20.5 11.0 6.7 6.7 7.8 19.9 4.5 19.9 12.7 10.3 20.3 13.8 4.6 6.5 12.3 8.2 13.2 7.7 16.9 13.7 15.4 4.4 24.4 10.3 11.0 13.7 4.5 4.3 7.9 25.9 25.0 11.6 4.9 8.6 6.6 3.4 4.2 5.8 11.6 15.4 10.7 4.5 7.3 8.4 0.7 6.0 16.7 9.9 9.2 10.7 14.0 13.0 9.5 6.3 12.7 11.8 10.8 2.6 11.8 17.3 5.9 10.7 7.9 9.4 10.6 10.4 12.2 10.5 10.6 9.2 9.6 9.9 8.4 10.9 11.1 16.6 28.9 3.2 30.0 8.2 4.1 11.4 14.9 10.8 7.3 9.7 9.9 52.5 15.7 16.8 11.0 0.0 20.5 6.6 9.4 52.8 13.0 2.9 13.1 5.4 12.3 6.1 15.8 36.6 6.7 10.5 6.7 6.6 8.1 0.0 23.5 9.7 25.7 9.4 1.7 39.2 13.2 8.2 13.9 3.8 2.0 8.1 8.4 5.4 14.0 6.3 11.6 10.3 15.1 25.8 7.2 13.4 5.7 4.7 6.2 18.1 34.1 22.5 7.2 0.0 9.8 6.6 8.5 12.0 9.8 4.5 10.7 7.9 13.2 15.0 9.0 SIX5 DMAHP ENSG00000177045 "SIX homeobox 5" Q8N196 19 45764785-45769252 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA042068 Approved NA NA "Cluster 72: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "HPA042068: AB_10795390" "unprognostic (3.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.39e-3)" "unprognostic (9.60e-3)" "unprognostic (2.11e-1)" "unprognostic (2.96e-3)" "unprognostic (1.00e-3)" "unprognostic (1.02e-3)" "unprognostic (3.90e-2)" "unprognostic (8.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.30e-1)" "unprognostic (1.69e-3)" "unprognostic (5.59e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-2)" "unprognostic (8.99e-2)" 19.1 23.5 8.8 5.8 8.4 0.6 20.5 8.5 10.0 37.5 13.5 35.8 6.7 34.6 8.7 14.7 37.8 8.1 25.2 7.6 8.5 20.9 24.6 12.6 4.2 11.2 10.5 45.8 41.0 9.3 15.9 8.4 8.5 34.0 4.3 0.6 28.0 15.9 16.0 12.7 14.2 12.6 9.9 12.1 25.4 8.0 9.1 2.3 29.4 5.7 2.9 30.8 22.5 7.9 3.3 19.3 25.6 39.2 16.0 15.9 13.2 7.3 15.5 11.1 9.7 4.8 12.4 1.8 7.0 11.9 13.6 7.5 7.7 8.4 3.7 9.3 11.6 2.1 18.7 13.8 14.1 0.5 11.9 15.6 13.1 7.2 9.2 16.8 9.4 7.6 9.0 3.9 3.2 10.6 2.6 18.2 17.4 10.4 10.9 9.7 2.3 7.9 12.1 4.1 1.6 10.5 21.7 10.7 16.8 10.1 10.0 18.8 5.7 11.0 10.3 10.0 8.1 4.7 5.1 1.9 15.9 0.9 12.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 8.4 8.5 10.0 7.6 8.5 11.2 10.5 8.5 9.9 9.1 7.9 5.2 0.0 7.2 7.5 1.0 3.2 5.4 7.9 4.6 0.1 11.6 14.7 0.3 11.5 3.4 5.5 0.0 6.1 0.3 2.1 3.9 6.2 0.4 7.3 14.9 5.2 3.0 0.0 0.0 6.0 13.1 9.1 4.1 8.3 0.0 11.0 6.8 7.0 1.1 5.0 0.0 8.6 2.0 0.8 1.4 1.2 15.8 0.9 0.0 3.7 0.0 3.1 0.0 0.0 0.1 5.0 2.1 12.8 5.5 6.1 0.7 1.9 4.0 0.5 0.0 8.2 8.8 0.5 3.5 4.2 2.6 4.0 0.8 4.5 5.0 1.4 SKOR1 "CORL1, FUSSEL15, LBXCOR1" ENSG00000188779 "SKI family transcriptional corepressor 1" P84550 15 67819704-67834582 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 5.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.6;Early spermatids: 20.5;Late spermatids: 36.2;Spermatocytes: 8.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 1.0;U-266/70: 2.4;U-266/84: 2.0;U-698: 2.1" "Group enriched" "Detected in some" 11 "cerebellum: 3.7;pons and medulla: 1.2" "Region enriched" "Detected in single" 5 "cerebellum: 5.0" HPA071150 Enhanced NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA071150: " "unprognostic (8.98e-2)" "unprognostic (4.15e-2)" "unprognostic (5.44e-7)" "unprognostic (1.76e-1)" "unprognostic (2.90e-2)" "unprognostic (2.45e-3)" "unprognostic (8.40e-5)" "unprognostic (5.51e-3)" "unprognostic (1.00e-1)" "unprognostic (8.13e-2)" "unprognostic (9.31e-2)" "unprognostic (1.93e-1)" "unprognostic (4.28e-5)" "unprognostic (1.96e-1)" "unprognostic (1.18e-1)" "unprognostic (1.59e-1)" "unprognostic (1.35e-1)" 0.5 0.4 0.4 0.0 0.3 0.3 0.5 5.5 1.2 0.7 0.0 0.7 0.2 0.7 0.1 0.2 0.6 0.1 0.3 0.4 0.8 0.3 0.2 0.4 0.0 2.5 0.5 0.9 0.4 0.0 1.1 0.1 1.6 0.5 0.0 0.5 0.3 0.1 0.4 0.8 0.5 0.1 2.1 0.4 0.4 1.1 0.3 0.2 0.4 0.0 0.0 0.5 0.5 0.9 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.4 0.1 0.0 0.0 1.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.1 0.2 0.4 0.0 0.0 0.1 0.3 0.1 0.5 0.0 0.0 0.1 0.8 0.0 0.0 0.2 0.1 0.1 0.5 0.1 0.0 0.2 0.1 0.1 2.4 2.0 2.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 5.5 1.2 0.4 0.8 2.5 0.5 1.6 2.1 0.3 0.9 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.6 0.7 0.2 0.1 5.6 0.0 0.0 0.0 0.0 0.1 0.1 0.1 1.9 0.0 20.5 0.0 0.1 0.4 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 36.2 0.9 0.2 0.0 0.0 0.0 0.2 0.0 1.0 0.6 0.0 0.0 0.7 0.1 0.0 0.0 3.0 0.0 0.1 0.0 0.5 0.3 8.0 0.3 0.1 0.4 0.0 0.0 0.2 0.1 0.1 SLAMF1 "CD150, SLAM" ENSG00000117090 "Signaling lymphocytic activation molecule family member 1" Q13291 1 160608106-160647295 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Host-virus interaction, Immunity, Innate immunity, Phagocytosis" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 76.6" "Cell type enhanced" "Detected in some" "B-cells: 29.8;Melanocytes: 14.2;monocytes: 22.9;Plasma cells: 49.2;T-cells: 35.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 66.3" "Group enriched" "Detected in many" 10 "B-cells: 22.7;T-cells: 66.3" "Cell line enriched" "Detected in some" 104 "HDLM-2: 195.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002438, HPA069319" Enhanced "Secreted to blood" NA NA 350000 "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB002438: AB_564011, HPA069319: AB_2732129" "unprognostic (2.99e-3)" "unprognostic (3.33e-4)" "unprognostic (2.93e-4)" "unprognostic (1.38e-4)" "unprognostic (5.87e-2)" "unprognostic (6.06e-5)" "unprognostic (1.64e-2)" "unprognostic (1.70e-3)" "unprognostic (1.69e-2)" "unprognostic (2.74e-4)" "unprognostic (6.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.24e-7)" "unprognostic (2.46e-1)" "unprognostic (8.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.18e-2)" 1.1 0.5 0.0 13.6 0.0 6.6 1.6 0.0 0.1 1.1 0.3 2.6 3.7 0.4 0.1 1.4 0.4 2.3 1.1 0.0 0.0 0.9 0.9 2.1 21.6 0.3 0.0 0.4 0.3 0.1 0.1 3.0 0.1 0.6 3.0 0.0 1.7 0.3 0.3 0.7 3.9 0.9 0.1 6.7 3.9 0.2 0.1 76.6 0.6 0.0 19.1 8.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 195.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.4 0.0 1.8 0.0 0.1 0.2 0.0 10.7 0.0 66.3 16.5 46.3 33.0 0.3 22.7 17.5 4.4 0.6 0.0 0.1 4.4 61.7 9.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 1.4 0.0 5.2 0.0 29.8 2.0 0.1 0.0 0.0 0.0 0.7 0.3 0.3 0.0 0.6 1.8 0.0 0.0 4.8 0.0 0.0 0.0 4.1 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 1.2 0.5 0.0 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.8 10.7 8.5 0.0 5.2 14.2 1.0 22.9 0.0 0.0 0.5 0.1 0.0 0.0 0.0 49.2 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.8 0.1 0.1 0.0 1.7 0.1 35.6 0.0 0.1 0.1 SLAMF7 "19A, CD319, CRACC, CS1" ENSG00000026751 "SLAM family member 7" Q9NQ25 1 160739057-160754821 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.6;lymphoid tissue: 62.0;stomach 1: 34.2" "Cell type enhanced" "Detected in many" "dendritic cells: 58.3;monocytes: 120.2;NK-cells: 76.2;Plasma cells: 240.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "U-266/70: 283.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015445, HPA055945, HPA061654" Enhanced Approved Vesicles NA NA 1200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB015445: AB_1121905, HPA055945: AB_2682980, HPA061654: AB_2684576" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (1.84e-3)" "unprognostic (2.12e-3)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (7.87e-2)" "unprognostic (7.19e-2)" "unprognostic (2.46e-2)" "prognostic favorable (3.93e-4)" "unprognostic (1.08e-1)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.57e-5)" "unprognostic (1.35e-1)" "unprognostic (3.91e-2)" "unprognostic (1.02e-1)" "unprognostic (1.50e-2)" 2.2 3.0 0.2 34.6 0.2 9.7 11.3 0.2 0.6 3.4 0.7 32.6 32.2 2.2 1.7 5.9 2.1 8.7 1.6 0.2 0.2 1.4 7.9 14.5 50.8 0.4 0.2 2.3 1.1 0.4 0.3 1.4 0.6 2.6 28.6 0.0 13.7 2.4 0.5 1.7 25.5 3.7 0.4 42.3 34.2 1.4 0.3 14.7 1.6 0.2 62.0 22.2 2.1 0.5 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 1.0 0.8 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.2 0.0 7.6 0.0 2.5 0.7 0.0 0.2 0.0 7.2 0.0 0.0 0.1 0.0 0.2 1.4 0.0 0.1 0.1 10.0 0.0 0.8 0.0 0.1 0.0 0.0 59.5 0.0 0.0 0.1 0.2 0.0 3.8 0.0 0.2 283.7 26.4 0.2 7.9 0.2 0.0 0.2 5.1 1.4 100.5 34.8 77.3 11.0 10.2 69.0 23.6 2.3 3.0 40.1 3.5 55.5 53.1 89.7 0.0 33.6 0.2 0.2 0.2 0.6 0.2 0.2 0.4 0.2 0.6 0.4 0.3 0.5 0.4 9.6 6.0 0.0 37.4 0.8 1.6 0.3 0.0 0.0 0.2 0.6 1.3 1.5 1.0 0.0 0.0 0.1 58.3 0.2 0.0 0.7 0.0 0.2 0.2 1.4 0.0 3.6 0.0 2.7 0.1 1.7 1.5 0.4 8.8 0.0 0.7 0.6 8.4 0.0 0.0 0.0 0.0 7.3 9.2 0.1 0.0 28.2 19.6 1.0 120.2 0.0 76.2 0.0 0.0 8.6 0.0 0.0 240.9 2.5 0.0 0.2 1.7 0.0 0.0 4.8 1.3 0.0 0.1 0.7 0.4 0.3 37.1 0.0 0.4 3.7 SLC10A3 "DXS253E, P3" ENSG00000126903 "Solute carrier family 10 member 3" P09131 X 154487306-154490690 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 63.6;Syncytiotrophoblasts: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "basophil: 218.6" "Lineage enriched" "Detected in all" 17 "granulocytes: 218.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021656 Approved Approved "Intermediate filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 51: Myeloid cells - Hemostasis" "Intermediate filaments" "HPA021656: AB_1856955" "unprognostic (1.60e-1)" "prognostic favorable (4.53e-4)" "prognostic unfavorable (4.15e-5)" "unprognostic (8.00e-3)" "prognostic unfavorable (9.97e-4)" "unprognostic (5.47e-2)" "unprognostic (2.28e-3)" "unprognostic (9.76e-2)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.42e-1)" "unprognostic (2.52e-3)" "unprognostic (6.23e-2)" "unprognostic (2.99e-1)" "unprognostic (7.29e-2)" "unprognostic (2.99e-2)" 23.3 22.9 6.1 13.1 6.2 34.0 21.0 6.8 7.9 27.1 5.8 22.5 13.9 29.6 18.4 31.2 22.8 21.3 23.2 5.9 6.1 20.6 10.3 22.7 15.1 7.4 6.8 40.8 22.8 9.6 18.8 21.1 7.4 22.9 8.3 2.0 17.4 15.7 18.3 42.9 18.7 13.5 6.9 19.3 18.9 8.9 8.1 9.8 20.6 9.4 11.2 31.8 26.0 7.7 66.4 27.0 7.3 38.3 25.2 27.6 48.9 49.2 29.2 32.5 32.3 25.0 31.8 51.0 91.1 46.8 41.3 55.9 24.4 24.7 8.6 32.7 11.8 15.9 36.0 20.3 47.0 19.0 24.9 34.8 28.1 29.9 15.8 28.5 22.6 8.7 17.6 48.6 21.6 90.0 10.2 17.0 5.9 32.4 54.9 16.8 19.9 38.8 24.7 24.2 6.8 12.0 29.8 55.4 13.0 8.5 17.9 15.0 29.5 38.0 23.9 89.6 63.2 34.3 35.6 52.8 40.9 39.6 20.2 218.6 4.5 21.1 12.9 6.5 9.6 5.3 8.5 9.2 3.9 5.2 6.0 5.9 6.1 8.8 5.6 9.5 6.4 6.3 6.1 6.2 6.8 7.9 5.9 6.1 7.4 6.8 7.4 6.9 8.1 7.7 13.3 3.2 7.0 2.3 21.1 22.6 27.1 15.2 50.7 2.8 13.7 11.8 4.0 15.7 7.3 18.4 6.2 49.5 17.4 22.1 7.9 17.8 3.6 13.0 14.8 15.8 10.2 11.1 1.6 19.4 63.6 21.2 13.7 21.0 12.7 15.8 16.8 2.3 19.4 3.3 1.4 15.5 4.1 8.4 19.6 1.2 27.1 22.7 3.6 1.0 13.2 3.0 23.7 1.5 1.6 20.9 16.0 13.2 19.8 14.1 17.2 10.4 6.9 1.9 6.6 12.1 14.3 1.9 2.9 45.5 27.8 103.0 24.5 5.4 11.7 23.5 SLC12A5 "KCC2, KIAA1176" ENSG00000124140 "Solute carrier family 12 member 5" Q9H2X9 20 46021690-46060150 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 145.8;retina: 117.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 244.0;Cone photoreceptor cells: 383.7;Excitatory neurons: 92.7;Inhibitory neurons: 91.3;Rod photoreceptor cells: 170.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 24.9;NB-4: 50.8;SK-BR-3: 24.8;U-2 OS: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072058 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA072058: AB_2686485" "unprognostic (2.01e-1)" "unprognostic (3.58e-1)" "unprognostic (7.55e-2)" "unprognostic (9.44e-4)" "prognostic unfavorable (5.60e-4)" "unprognostic (2.48e-1)" "unprognostic (5.16e-3)" "unprognostic (3.61e-1)" "unprognostic (2.49e-1)" "unprognostic (6.63e-2)" "unprognostic (3.72e-3)" "unprognostic (5.61e-4)" "unprognostic (8.78e-4)" "unprognostic (3.25e-2)" "unprognostic (9.22e-2)" "unprognostic (1.99e-1)" "unprognostic (2.34e-2)" 1.5 26.7 101.3 0.9 103.5 0.4 1.0 97.6 145.8 0.9 14.9 1.4 1.0 0.7 0.9 0.4 0.5 0.7 5.1 107.0 96.6 1.1 1.2 2.5 2.2 76.3 80.5 2.3 2.2 1.8 41.5 2.0 69.9 1.0 0.9 117.4 0.7 0.5 0.4 0.6 1.6 0.4 69.3 3.0 1.9 7.8 86.7 2.9 0.7 0.2 1.4 0.6 0.7 88.4 0.0 15.2 6.6 4.9 0.6 0.0 1.5 0.6 0.0 0.0 0.5 2.0 0.0 5.8 22.5 0.4 5.9 1.4 4.3 2.3 0.4 3.7 5.7 4.9 3.0 24.9 2.5 0.0 6.5 0.8 0.0 0.0 0.3 10.0 1.4 5.4 9.3 0.0 0.0 23.1 3.5 50.8 2.4 2.1 7.7 5.8 4.2 1.3 2.3 0.0 8.1 11.5 2.9 24.8 7.9 6.0 9.0 14.4 2.3 2.7 28.0 0.2 1.1 0.0 4.2 8.2 5.9 5.9 0.2 0.0 0.6 0.0 1.1 0.4 0.5 0.4 0.1 0.1 0.1 0.5 2.4 1.3 0.0 0.4 0.1 0.0 1.9 0.3 101.3 103.5 97.6 145.8 107.0 96.6 76.3 80.5 69.9 69.3 86.7 88.4 2.2 0.0 0.0 10.4 0.4 0.5 0.0 0.0 0.0 244.0 0.8 2.2 1.2 0.0 0.0 0.0 383.7 1.6 0.9 0.0 1.9 0.1 1.9 0.4 0.1 2.9 19.9 4.4 92.7 0.2 2.5 0.4 1.5 0.6 0.0 14.4 4.6 1.3 19.8 13.5 91.3 0.7 0.0 2.6 5.3 6.1 0.0 3.4 5.4 10.3 0.6 28.2 0.0 3.5 6.3 0.4 0.0 0.0 0.8 0.2 0.0 0.3 0.0 170.9 0.0 0.0 2.2 4.2 7.7 0.1 0.6 1.6 1.0 8.5 0.3 0.1 SLC1A3 "EA6, EAAT1, GLAST" ENSG00000079215 "Solute carrier family 1 member 3" P43003 5 36596588-36688334 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 10 "brain: 776.8;choroid plexus: 400.6;retina: 221.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1735.2;Microglial cells: 332.6;Muller glia cells: 472.6;Oligodendrocyte precursor cells: 237.7;Oligodendrocytes: 249.0" "Cancer enriched" "Detected in all" 21 "glioma: 168.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 1.5;intermediate monocyte: 1.2;myeloid DC: 1.6" "Group enriched" "Detected in many" 16 "dendritic cells: 1.6;monocytes: 1.5" "Cell line enhanced" "Detected in many" "AF22: 50.0;CACO-2: 112.6;HaCaT: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002573, HPA037467, HPA037468" Enhanced Supported Approved Nucleoli,Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Vesicles" "CAB002573: AB_564088, HPA037467: AB_10795027, HPA037468: AB_10671371" "unprognostic (1.23e-1)" "unprognostic (2.15e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (7.70e-2)" "unprognostic (3.89e-3)" "unprognostic (2.36e-1)" "unprognostic (1.24e-1)" "unprognostic (2.84e-2)" "unprognostic (4.17e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.17e-2)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" 30.7 16.4 500.4 7.4 544.2 3.3 17.7 549.4 776.8 8.7 400.6 3.0 0.5 1.6 1.1 10.5 6.0 8.0 45.4 514.6 502.5 2.2 3.8 10.2 17.4 477.6 510.1 12.6 5.0 2.2 18.1 20.3 502.4 3.2 1.1 221.1 4.7 4.7 14.1 6.0 3.2 4.1 495.4 9.3 2.2 1.2 532.8 3.6 3.4 9.2 5.4 7.0 5.3 494.9 1.3 0.2 50.0 5.3 5.9 14.3 37.7 0.3 0.0 2.4 4.9 112.6 5.6 0.0 27.8 2.3 1.0 71.4 16.9 9.1 2.2 1.8 33.0 0.0 0.5 0.0 2.5 1.3 0.6 26.9 34.5 14.4 5.3 1.8 0.0 1.1 0.0 0.2 8.7 0.2 0.1 0.1 6.0 0.1 5.9 0.0 0.5 0.0 0.1 3.1 4.7 0.0 5.1 14.6 2.1 24.4 0.2 3.1 0.0 6.2 10.3 0.1 20.7 0.0 0.0 0.3 21.7 37.7 12.6 0.0 1.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 500.4 544.2 549.4 776.8 514.6 502.5 477.6 510.1 502.4 495.4 532.8 494.9 1.1 3.2 0.5 1735.2 0.7 10.7 14.3 19.0 83.1 7.1 3.7 3.4 36.0 0.0 3.1 0.0 2.1 32.9 0.1 0.0 0.0 0.8 0.7 16.3 1.2 8.9 0.0 0.8 2.6 0.0 15.9 7.8 2.0 11.7 0.0 0.2 1.1 0.5 41.2 3.3 4.7 0.0 0.0 77.6 5.9 4.1 4.4 59.6 7.2 332.6 3.3 472.6 0.0 237.7 249.0 0.3 0.0 0.0 0.7 5.2 0.0 0.0 5.3 19.1 6.6 2.6 3.1 0.3 0.3 32.7 7.1 9.2 1.0 20.7 0.0 3.6 SLC1A6 EAAT4 ENSG00000105143 "Solute carrier family 1 member 6" P48664 19 14950034-15022990 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 88.2;testis: 28.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.1;Early spermatids: 35.3;Horizontal cells: 23.5;Late spermatids: 31.8;Syncytiotrophoblasts: 40.0" "Cancer enriched" "Detected in some" 7 "urothelial cancer: 5.2" "Region enriched" "Detected in all" 6 "cerebellum: 88.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 7.4;NTERA-2: 6.1;U-698: 28.3" "Region enriched" "Detected in all" 6 "cerebellum: 136.3" "Region enhanced" "Detected in all" "cerebellum: 53.8" "HPA041505, HPA044066" Enhanced Supported Supported "Plasma membrane,Intermediate filaments" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Intermediate filaments" "HPA041505: AB_2677520, HPA044066: AB_2678796" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.94e-3)" "unprognostic (8.90e-2)" "unprognostic (6.52e-4)" "unprognostic (1.55e-1)" "unprognostic (5.40e-3)" "unprognostic (1.11e-2)" "unprognostic (9.92e-2)" "unprognostic (1.35e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (6.88e-6)" 0.1 0.2 9.1 0.2 10.8 0.9 0.4 88.2 14.4 0.1 0.5 0.2 0.3 0.4 1.7 0.1 0.2 0.2 0.2 14.5 5.0 0.1 0.2 0.2 0.3 3.7 7.5 0.3 0.6 0.9 0.3 0.7 8.1 0.5 0.3 2.3 0.4 0.5 0.3 8.6 0.3 0.2 3.2 0.4 0.2 28.0 6.6 0.2 0.3 0.1 0.3 0.1 0.1 5.1 0.1 0.1 0.3 0.4 0.2 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 1.4 7.4 0.2 0.1 0.2 0.1 0.2 0.4 0.3 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.6 0.1 0.6 0.0 0.5 6.1 0.0 0.1 0.1 0.1 0.1 0.1 0.3 0.5 0.2 0.2 2.8 0.0 1.1 0.3 0.1 0.0 0.3 1.1 0.3 0.1 0.5 0.1 28.3 0.1 0.3 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 9.1 10.8 88.2 14.4 14.5 5.0 3.7 7.5 8.1 3.2 6.6 5.1 0.0 0.0 0.0 0.7 0.0 3.2 0.7 0.0 0.0 17.1 0.0 0.1 2.1 0.0 0.0 1.8 0.0 1.9 0.0 0.0 0.0 0.0 35.3 0.0 0.1 0.1 0.0 0.0 8.2 0.4 9.9 0.4 0.0 0.0 0.0 5.8 0.0 0.0 0.5 23.5 8.6 0.0 0.0 0.0 0.7 31.8 0.6 0.0 0.0 1.0 0.0 0.7 0.0 4.5 0.9 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.0 0.8 0.0 0.0 0.4 2.2 6.3 0.0 6.8 40.0 0.0 0.0 0.0 0.1 SLC25A15 "D13S327, HHH, ORC1, ORNT1" ENSG00000102743 "Solute carrier family 25 member 15" Q9Y619 13 40789412-40812460 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 37.6;liver: 88.3;pancreas: 52.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 44.5;Hepatocytes: 39.8;Proximal enterocytes: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042146 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA042146: AB_2677874" "unprognostic (4.17e-1)" "unprognostic (4.50e-2)" "unprognostic (2.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.38e-1)" "unprognostic (3.85e-1)" "prognostic favorable (2.16e-4)" "unprognostic (2.34e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (1.12e-1)" "unprognostic (2.37e-2)" "prognostic favorable (1.74e-4)" "unprognostic (4.04e-3)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "prognostic unfavorable (5.46e-4)" 2.3 1.4 2.0 4.1 2.2 5.6 4.6 2.3 2.5 2.1 2.3 5.9 37.6 3.1 1.1 3.2 2.6 5.0 2.8 1.9 2.6 5.6 88.3 2.3 4.8 2.6 2.3 2.9 52.1 3.4 1.3 2.8 2.5 2.8 6.5 2.8 3.4 1.8 5.9 3.7 26.7 3.4 2.1 2.5 5.5 9.4 2.4 5.3 17.3 6.0 5.3 2.6 1.6 2.9 7.4 14.7 16.5 21.3 6.5 8.2 17.3 5.6 2.9 6.8 3.9 17.6 15.2 48.0 6.4 10.3 12.7 12.6 26.6 15.5 7.0 11.9 12.4 37.0 8.6 26.6 12.7 15.0 5.3 9.0 8.6 9.6 21.9 4.6 11.2 23.8 18.1 7.8 11.8 28.2 10.2 9.9 33.2 32.7 7.9 25.5 12.0 10.6 11.7 7.0 7.7 20.1 10.2 18.4 10.1 11.5 13.6 23.2 8.4 8.4 12.1 12.7 17.0 8.9 9.6 27.9 8.4 11.4 16.4 1.3 0.5 0.1 1.6 0.9 1.0 0.6 1.0 1.1 1.1 0.7 1.0 2.0 0.7 1.4 0.5 0.5 0.9 0.5 2.0 2.2 2.3 2.5 1.9 2.6 2.6 2.3 2.5 2.1 2.4 2.9 0.3 3.2 0.5 3.9 1.3 0.3 1.0 0.8 2.2 1.4 2.1 1.4 1.1 1.5 0.2 0.0 0.0 2.2 1.3 0.6 7.9 2.1 4.6 1.2 2.1 0.9 1.2 9.0 2.4 4.3 44.5 1.0 1.5 2.1 0.0 1.5 0.7 39.8 1.7 0.0 4.3 0.6 2.0 1.6 0.3 6.8 0.6 1.0 1.8 1.0 0.0 0.4 2.1 5.0 1.4 1.7 2.7 0.0 6.2 1.6 19.0 4.3 0.1 1.9 0.0 1.0 1.1 5.4 9.3 2.1 0.1 1.5 3.2 4.3 3.5 0.8 SLC25A23 "APC2, FLJ30339, MGC2615" ENSG00000125648 "Solute carrier family 25 member 23" Q9BV35 19 6436079-6465203 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 238.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.2;Proximal enterocytes: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009675, HPA050883" Approved Supported Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA009675: AB_2668252, HPA050883: AB_2681260" "unprognostic (3.51e-1)" "unprognostic (1.53e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.05e-2)" "unprognostic (3.65e-3)" "unprognostic (3.43e-2)" "unprognostic (1.31e-3)" "unprognostic (1.27e-1)" "unprognostic (3.82e-1)" "unprognostic (1.30e-1)" "unprognostic (3.25e-1)" "prognostic favorable (1.10e-12)" "unprognostic (8.95e-2)" "unprognostic (3.20e-1)" "unprognostic (5.44e-2)" "unprognostic (4.22e-1)" 28.8 38.0 144.8 12.0 238.7 0.8 18.0 77.5 200.1 32.1 72.0 94.4 39.3 41.8 24.0 64.7 36.6 21.4 79.0 206.5 95.1 45.0 38.5 24.0 9.2 108.8 98.2 33.6 24.2 58.8 22.2 4.7 109.5 35.0 49.1 41.2 68.9 40.0 90.8 33.5 40.5 65.5 82.7 11.9 41.3 9.5 101.4 7.2 60.7 78.2 31.2 55.8 31.1 115.8 58.2 22.9 32.2 101.9 42.3 18.6 14.9 17.0 26.4 31.0 37.2 58.2 37.1 32.2 40.0 41.3 34.1 48.0 66.3 39.0 24.3 0.1 58.6 23.2 46.7 46.2 39.2 1.6 52.5 53.3 33.4 27.6 12.0 62.9 32.8 34.7 68.8 39.4 6.2 41.6 20.7 32.8 23.6 61.0 71.1 10.0 8.8 49.4 83.3 10.2 2.4 31.9 11.7 70.8 30.0 34.8 37.1 50.1 11.7 9.8 41.8 2.6 11.2 7.3 10.7 28.3 4.5 54.2 15.6 0.5 0.0 0.0 2.0 0.0 0.4 1.0 1.1 0.9 0.2 0.4 1.5 1.4 0.0 0.3 0.0 0.4 1.3 0.4 144.8 238.7 77.5 200.1 206.5 95.1 108.8 98.2 109.5 82.7 101.4 115.8 6.2 9.6 20.9 11.8 7.0 10.5 8.8 11.5 12.0 13.1 18.9 15.6 39.5 47.1 10.0 46.0 8.4 1.4 4.5 164.2 19.6 54.7 15.9 8.2 6.4 8.0 13.8 1.3 24.7 28.5 1.8 10.2 12.8 17.5 7.0 17.9 16.1 38.0 2.7 8.4 17.9 34.5 10.2 3.0 2.6 71.2 19.0 1.4 17.8 12.2 1.0 28.7 4.1 17.1 12.6 55.5 57.9 29.3 17.6 13.6 106.8 28.7 6.4 22.0 13.1 12.1 12.7 0.5 4.6 34.1 23.3 0.8 5.2 39.5 34.2 30.3 SLC25A25 "KIAA1896, MCSC, PCSCL" ENSG00000148339 "Solute carrier family 25 member 25" Q6KCM7 9 128068201-128109245 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 136.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020381 Uncertain Supported Vesicles,Mitochondria "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 16: U-266 - Nucleosome" "Cluster 44: Endometrium - Transcription" "Vesicles, Mitochondria" "HPA020381: AB_1857037" "unprognostic (4.62e-2)" "unprognostic (2.66e-2)" "unprognostic (2.56e-2)" "unprognostic (1.59e-1)" "unprognostic (2.89e-1)" "unprognostic (1.40e-1)" "prognostic favorable (1.01e-4)" "unprognostic (1.20e-1)" "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (4.96e-2)" "unprognostic (3.70e-2)" "prognostic favorable (4.65e-6)" "unprognostic (1.21e-1)" "unprognostic (1.05e-2)" "unprognostic (1.66e-3)" "unprognostic (1.42e-2)" 55.3 22.9 16.0 12.5 16.5 9.5 22.9 14.7 19.7 33.2 10.6 17.2 11.9 26.8 3.3 35.0 40.7 39.9 12.8 18.1 17.4 28.6 136.5 27.9 11.2 19.9 18.1 25.3 82.6 19.6 45.7 11.5 17.9 15.2 7.8 31.2 16.5 14.2 82.0 24.4 18.3 26.3 15.4 15.6 23.7 7.6 19.6 15.3 18.9 21.1 6.2 19.0 21.4 14.9 9.5 9.8 13.6 19.8 10.1 8.6 9.0 19.3 17.8 15.9 10.5 17.7 9.7 12.2 5.8 9.0 8.8 16.6 10.8 6.3 6.0 14.3 8.9 7.1 21.6 10.7 16.0 8.3 15.7 11.0 6.0 15.5 11.3 5.2 10.9 20.1 26.1 25.7 10.1 22.9 14.7 8.4 13.8 30.5 15.1 14.3 11.6 26.1 6.1 9.8 33.6 14.5 20.2 12.9 27.8 5.3 14.2 4.7 7.0 17.9 10.6 13.6 19.3 22.3 42.2 13.2 12.1 4.4 15.0 2.6 1.7 0.9 3.0 5.1 1.6 1.2 3.4 3.1 3.1 1.8 2.7 4.9 0.3 1.0 6.1 1.0 2.7 3.2 16.0 16.5 14.7 19.7 18.1 17.4 19.9 18.1 17.9 15.4 19.6 14.9 59.3 22.4 34.2 17.6 9.3 26.1 46.2 24.3 56.3 18.8 71.7 73.5 3.2 58.6 22.8 20.2 127.2 10.1 7.6 45.6 11.7 11.2 0.3 72.0 34.5 44.7 51.7 11.0 19.7 11.5 12.9 21.0 43.8 110.3 8.2 18.7 26.0 84.5 9.1 18.5 20.5 26.5 28.5 20.1 42.9 1.5 9.3 16.8 21.4 13.1 12.6 15.2 12.3 11.1 2.4 12.1 42.7 8.2 14.5 28.6 47.7 10.2 30.8 70.4 19.7 48.1 40.3 5.6 7.9 89.5 43.0 23.0 14.2 11.9 22.3 58.3 SLC25A41 "APC4, FLJ40442, MGC34725" ENSG00000181240 "Solute carrier family 25 member 41" Q8N5S1 19 6426037-6433779 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 6.3;choroid plexus: 4.3;testis: 2.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 92.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 3.0;U-937: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043591 Uncertain NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA043591: AB_10964585" "unprognostic (1.87e-3)" "unprognostic (2.52e-3)" "unprognostic (6.81e-2)" "unprognostic (8.75e-2)" "unprognostic (2.67e-1)" "unprognostic (8.29e-4)" "unprognostic (4.43e-3)" "unprognostic (2.81e-2)" "unprognostic (9.26e-2)" "unprognostic (6.85e-2)" "unprognostic (2.19e-3)" "unprognostic (3.11e-2)" "unprognostic (2.03e-1)" "unprognostic (1.56e-1)" "unprognostic (3.63e-2)" "unprognostic (2.11e-1)" "unprognostic (1.24e-1)" 0.1 0.1 4.7 0.0 5.3 0.0 0.0 4.6 6.3 0.2 4.3 0.6 0.0 0.1 0.0 0.3 0.2 0.0 0.3 4.8 4.7 0.2 0.3 0.0 0.0 4.6 4.6 0.3 0.1 0.0 0.2 0.0 4.9 0.4 0.0 0.3 0.1 0.1 0.3 0.2 0.2 0.1 4.4 0.1 0.2 2.1 4.5 0.0 0.2 0.0 0.0 0.3 0.2 4.4 0.1 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.0 0.2 0.6 0.0 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 5.3 4.6 6.3 4.8 4.7 4.6 4.6 4.9 4.4 4.5 4.4 0.0 0.0 0.0 2.0 0.1 0.0 0.1 0.3 0.0 1.0 0.2 0.3 0.5 0.0 0.0 0.0 2.1 0.4 0.1 0.4 0.0 0.3 92.2 0.1 0.1 0.0 0.0 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.1 3.3 4.5 0.4 0.0 0.0 0.0 20.6 0.9 0.1 0.0 0.0 0.0 1.1 0.0 1.0 1.6 0.6 0.2 0.0 0.0 0.2 0.2 0.2 0.1 1.2 0.0 0.1 0.1 0.3 0.6 0.0 0.3 0.5 0.0 0.0 0.4 0.1 SLC26A11 ENSG00000181045 "Solute carrier family 26 member 11" Q86WA9 17 80219699-80253500 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 58.4;Rod photoreceptor cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029893 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" Nucleoplasm "HPA029893: AB_10600809" "unprognostic (5.86e-2)" "unprognostic (6.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (3.80e-2)" "unprognostic (2.63e-3)" "prognostic unfavorable (1.82e-6)" "unprognostic (2.05e-2)" "unprognostic (3.54e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.43e-5)" "unprognostic (2.86e-1)" "unprognostic (3.50e-1)" "unprognostic (9.54e-3)" "unprognostic (8.40e-2)" "unprognostic (8.69e-2)" "unprognostic (7.32e-2)" 12.2 36.5 27.4 8.9 24.8 16.4 11.8 14.1 23.2 16.3 21.9 12.1 7.2 11.6 8.9 7.5 13.5 7.6 7.1 21.1 45.5 19.1 10.2 18.8 14.1 27.8 33.3 22.5 10.6 11.8 35.1 9.0 30.1 16.8 4.1 11.6 11.3 9.2 5.9 13.0 11.2 6.0 17.7 22.6 10.0 4.8 42.2 3.4 24.8 3.6 5.6 11.6 12.1 17.4 0.7 12.4 14.3 11.1 7.1 5.2 16.1 6.7 8.4 15.6 9.4 13.6 2.5 0.1 13.1 7.4 11.3 4.4 8.0 5.2 6.1 15.7 14.4 0.0 17.5 13.5 18.6 0.0 2.2 9.5 8.4 7.5 3.4 1.4 13.3 2.7 6.4 16.8 9.3 11.6 0.6 0.3 6.5 3.5 11.7 0.5 1.6 5.7 14.2 13.6 5.4 16.9 6.8 17.0 18.3 22.0 20.4 0.3 9.9 11.8 6.9 10.4 0.9 17.8 7.4 1.8 6.2 0.0 10.1 0.0 1.0 0.0 0.7 0.4 1.1 0.2 1.2 1.0 0.6 0.1 1.9 0.8 0.0 0.0 0.1 0.0 1.7 0.9 27.4 24.8 14.1 23.2 21.1 45.5 27.8 33.3 30.1 17.7 42.2 17.4 8.8 6.4 13.4 22.2 3.9 4.6 8.9 5.0 5.2 27.2 9.6 9.9 2.5 5.7 5.6 12.9 58.4 14.5 5.6 3.2 1.9 7.5 0.6 7.1 7.0 12.4 10.2 2.7 13.4 6.0 8.8 8.1 3.6 11.6 1.3 15.4 8.2 2.2 15.2 3.3 17.2 3.2 8.2 11.4 10.5 0.7 17.1 15.1 3.6 12.2 4.2 22.8 5.2 12.1 13.3 3.4 3.9 12.4 2.2 9.0 7.0 6.0 4.4 40.8 32.9 6.4 7.7 0.2 5.3 2.4 4.7 26.0 8.2 16.4 2.6 5.3 SLC2A14 "GLUT14, SLC2A3P3" ENSG00000173262 "Solute carrier family 2 member 14" Q8TDB8 12 7812512-7891148 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis, Sugar transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 81.3" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 65.7" "Cancer enriched" "Detected in single" 35 "testis cancer: 7.1" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Immune cell enhanced" "Detected in some" "basophil: 3.7;neutrophil: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 18.4;CACO-2: 31.0;SuSa: 35.5" HPA006539 Supported Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" "HPA006539: AB_1078984" "unprognostic (2.52e-1)" "unprognostic (4.74e-3)" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (1.82e-3)" "unprognostic (8.62e-2)" "unprognostic (7.15e-2)" "unprognostic (1.89e-1)" "unprognostic (9.91e-3)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "unprognostic (8.46e-4)" "unprognostic (3.92e-2)" "unprognostic (3.41e-1)" "unprognostic (3.26e-2)" "unprognostic (1.22e-2)" 0.8 5.7 0.7 0.3 0.9 6.2 0.9 4.7 1.0 0.2 1.8 0.9 0.2 0.2 0.2 1.5 0.4 0.9 0.7 1.5 0.9 0.6 3.0 0.5 0.5 0.2 0.1 2.7 6.6 0.0 0.4 1.1 0.5 1.2 0.5 1.4 0.1 0.1 0.5 0.7 0.5 0.5 0.0 0.3 0.2 81.3 1.3 0.2 0.2 0.1 0.2 1.0 0.3 0.5 0.4 1.5 0.7 0.4 0.3 0.8 18.4 0.2 0.0 0.0 0.5 31.0 0.2 0.1 0.8 0.0 0.3 0.2 0.1 0.0 0.0 0.7 0.2 3.3 1.2 8.1 0.1 2.0 4.5 0.0 0.2 0.2 0.0 0.1 0.0 1.1 3.6 0.8 0.0 0.7 0.4 1.6 3.6 0.1 0.0 0.2 0.1 1.1 0.0 0.5 0.6 0.2 0.5 0.7 0.1 35.5 0.1 2.7 0.5 0.1 3.0 0.5 0.5 3.0 1.3 0.6 0.9 0.1 0.6 3.7 0.4 1.0 0.6 0.1 0.6 0.3 0.5 0.4 0.2 0.3 0.3 0.4 3.4 0.6 0.1 0.2 1.0 0.2 0.7 0.9 4.7 1.0 1.5 0.9 0.2 0.1 0.5 0.0 1.3 0.5 2.1 0.0 1.1 0.0 0.9 0.6 0.0 0.0 0.0 0.1 0.1 0.3 2.4 0.0 0.0 0.0 4.2 0.4 0.5 0.1 0.0 0.0 8.9 0.1 1.3 3.2 0.0 6.9 1.9 1.5 1.5 1.9 0.0 0.2 9.5 6.4 5.3 0.5 0.2 0.0 2.2 0.0 0.0 2.5 12.2 5.4 0.3 1.4 1.8 1.9 0.0 0.1 0.0 0.5 0.4 0.3 5.7 2.6 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.2 2.7 65.7 3.1 0.0 0.1 0.4 3.6 4.2 0.1 0.0 SLC2A5 GLUT5 ENSG00000142583 "Solute carrier family 2 member 5" P22732 1 9035106-9088478 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 97.3;intestine: 109.1;skeletal muscle: 78.8;testis: 76.4" "Cell type enhanced" "Detected in many" "Early spermatids: 64.3;Paneth cells: 55.6;Plasma cells: 35.3;Proximal enterocytes: 189.4;Spermatocytes: 83.2" "Group enriched" "Detected in many" 6 "glioma: 11.0;renal cancer: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 23.3" "Lineage enriched" "Detected in many" 5 "B-cells: 23.3" "Group enriched" "Detected in some" 5 "Daudi: 190.3;THP-1: 47.8;U-266/70: 154.0;U-698: 178.2;U-937: 68.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005449, HPA075145" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA005449: AB_1078985, HPA075145: " "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (8.00e-3)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.47e-2)" "unprognostic (5.35e-2)" "unprognostic (4.18e-1)" "unprognostic (6.85e-2)" "unprognostic (3.77e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.44e-5)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (8.19e-3)" "unprognostic (8.61e-2)" 7.7 3.4 9.2 5.4 9.2 97.3 5.1 10.5 11.8 2.6 10.1 4.8 109.1 1.3 10.5 3.9 2.6 1.1 2.3 10.3 12.0 38.4 0.6 1.2 20.4 24.1 14.5 2.8 0.6 1.5 2.9 4.9 20.4 15.1 3.6 2.7 2.4 5.1 78.8 6.9 85.3 4.4 14.3 5.6 0.9 76.4 16.1 1.7 0.8 65.9 18.3 3.0 4.2 19.6 0.3 0.1 0.0 0.2 0.2 1.2 0.5 0.2 0.7 0.0 0.6 1.3 0.0 190.3 0.2 0.4 0.1 0.4 1.7 0.1 0.4 25.1 0.2 0.2 3.4 0.0 0.3 3.0 1.6 2.7 2.6 0.6 0.0 2.9 0.0 0.1 0.3 2.0 0.0 0.0 0.1 10.0 0.2 0.0 0.2 4.9 0.0 5.9 0.2 2.0 0.6 0.3 0.3 0.5 0.7 0.1 0.3 47.8 0.2 3.0 0.9 0.5 0.2 154.0 0.2 178.2 0.2 68.2 0.2 4.8 2.5 0.2 0.2 0.5 0.2 4.3 0.2 0.2 0.9 23.3 0.2 0.2 1.4 0.3 0.1 0.2 0.1 1.2 9.2 9.2 10.5 11.8 10.3 12.0 24.1 14.5 20.4 14.3 16.1 19.6 0.3 0.0 0.0 2.0 5.2 2.0 2.0 0.2 10.2 0.0 0.1 0.4 1.9 0.0 0.0 1.8 0.0 0.1 0.0 1.4 7.9 0.3 64.3 0.1 0.3 4.9 1.2 0.0 1.0 0.0 1.1 0.8 0.0 0.4 1.3 0.1 0.4 0.1 4.3 0.0 1.2 7.6 0.0 0.8 1.2 19.3 2.8 2.7 0.0 31.9 0.6 0.6 0.0 2.5 0.9 0.6 55.6 0.4 35.3 2.1 189.4 24.2 0.0 0.1 6.6 2.1 0.4 83.2 8.2 2.7 0.6 0.5 0.3 0.3 8.0 0.2 SLC35A2 "UGALT, UGAT, UGT, UGT1, UGT2, UGTL" ENSG00000102100 "Solute carrier family 35 member A2" P78381 X 48903180-48911958 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036087 Approved Supported "Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "HPA036087: AB_10604093" "prognostic unfavorable (3.16e-4)" "unprognostic (3.34e-1)" "unprognostic (4.88e-3)" "unprognostic (1.11e-1)" "unprognostic (8.15e-3)" "unprognostic (4.25e-3)" "prognostic unfavorable (9.64e-5)" "unprognostic (3.47e-1)" "unprognostic (2.50e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-3)" "unprognostic (9.58e-2)" "unprognostic (3.16e-2)" "prognostic favorable (8.23e-4)" "unprognostic (1.38e-1)" "unprognostic (1.61e-1)" "unprognostic (5.13e-2)" 15.8 20.5 13.7 12.7 14.3 15.9 14.9 14.3 14.8 18.7 19.4 29.3 17.3 13.1 28.4 24.7 32.6 15.2 15.0 14.5 15.8 19.8 31.8 18.2 11.4 14.6 15.0 9.3 30.0 24.7 21.3 19.9 15.4 17.1 28.2 3.1 23.8 14.8 14.0 21.9 18.0 11.7 14.4 14.7 25.0 7.1 15.9 11.8 15.4 7.2 14.7 19.8 15.4 15.9 48.8 55.2 18.8 27.3 36.5 31.6 29.7 49.7 54.1 51.3 59.9 64.0 84.5 18.8 22.2 54.2 64.4 67.0 51.7 40.0 39.7 27.9 34.0 20.5 33.1 49.6 47.8 38.7 40.9 35.7 69.9 48.6 39.8 28.9 30.6 25.9 38.7 29.8 37.6 47.1 20.5 35.0 39.7 55.3 67.7 22.3 35.5 61.1 44.4 39.1 21.8 36.1 52.9 54.5 28.7 35.1 80.8 30.7 28.2 30.3 30.6 55.4 27.5 45.1 32.8 19.6 38.4 34.1 40.3 18.1 22.3 40.0 15.3 23.4 15.8 10.7 12.6 13.9 27.7 9.9 8.3 14.6 24.2 13.8 17.5 27.7 13.1 11.9 13.7 14.3 14.3 14.8 14.5 15.8 14.6 15.0 15.4 14.4 15.9 15.9 16.2 9.6 17.0 3.3 13.1 14.1 11.7 29.0 2.8 4.5 26.5 10.9 5.2 10.0 23.5 16.5 0.0 31.0 15.6 24.1 3.9 27.4 3.3 24.2 12.0 13.5 12.7 19.0 2.6 32.3 30.6 14.0 18.8 16.8 2.5 8.0 11.0 15.6 23.4 6.7 2.5 31.5 28.5 10.1 14.5 1.3 9.9 12.3 10.6 4.7 21.9 9.4 8.2 4.5 4.4 27.1 19.7 10.9 19.3 18.7 17.8 10.5 50.5 5.7 6.6 9.7 19.4 10.3 6.8 10.9 17.5 48.0 13.8 12.2 21.7 23.4 SLC37A3 DKFZp761N0624 ENSG00000157800 "Solute carrier family 37 member 3" Q8NCC5 7 140293693-140404433 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (2.39e-1)" "prognostic unfavorable (9.54e-4)" "unprognostic (1.44e-1)" "unprognostic (5.59e-2)" "unprognostic (2.69e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (4.78e-5)" "unprognostic (1.97e-1)" "unprognostic (2.94e-1)" "unprognostic (3.78e-2)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" "unprognostic (2.16e-2)" "unprognostic (3.31e-1)" "unprognostic (3.82e-1)" "unprognostic (1.49e-1)" "unprognostic (5.50e-2)" 19.2 10.2 10.6 10.6 11.5 12.3 21.5 10.9 14.0 30.2 7.4 26.4 14.1 44.0 23.9 11.4 23.4 19.1 12.8 10.8 11.3 15.8 12.8 16.5 9.1 10.3 9.3 20.7 25.7 35.0 17.1 21.8 10.6 14.7 24.5 11.3 23.3 12.7 7.8 13.5 16.4 31.9 8.9 15.7 18.4 7.4 11.7 11.7 21.3 9.9 10.6 22.1 18.3 11.0 18.0 29.9 30.3 53.3 42.7 46.6 36.2 26.3 30.8 17.9 26.6 23.9 38.1 2.7 32.6 24.0 45.8 14.5 18.5 32.0 27.3 40.6 27.1 3.5 7.8 24.1 35.9 0.2 9.7 36.8 32.3 19.0 22.0 31.2 27.9 15.5 18.2 7.3 27.8 34.3 17.5 1.6 44.9 43.2 18.4 9.5 8.1 8.2 34.5 37.0 29.8 36.7 7.3 29.5 29.7 32.3 15.9 1.7 32.0 20.4 14.8 51.8 27.3 14.0 28.4 6.9 21.6 0.2 47.7 7.6 3.6 3.7 6.5 2.0 3.5 2.3 6.9 5.1 3.0 1.7 7.3 5.5 12.3 5.9 1.3 0.9 8.6 3.6 10.6 11.5 10.9 14.0 10.8 11.3 10.3 9.3 10.6 8.9 11.7 11.0 8.5 9.6 12.4 14.4 6.0 15.2 39.8 11.8 8.6 11.4 12.1 8.6 5.1 10.0 16.1 12.9 10.4 17.5 5.8 21.0 1.9 22.3 1.6 24.9 43.8 11.6 21.6 6.1 37.1 26.9 26.4 30.6 19.9 21.3 8.2 15.0 13.2 7.3 4.0 13.5 29.0 22.2 14.2 5.1 9.7 2.3 20.2 3.3 19.6 13.1 7.4 3.6 11.3 26.7 22.4 28.6 14.7 13.5 4.2 31.4 11.2 5.7 18.4 9.0 6.6 15.1 16.9 4.6 5.9 8.5 12.4 13.1 10.6 5.1 18.1 37.4 SLC38A1 "ATA1, NAT2, SAT1" ENSG00000111371 "Solute carrier family 38 member 1" Q9H2H9 12 46183063-46270017 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 443.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-698: 386.1" "Low region specificity" "Detected in all" "HPA039460, HPA052272" Uncertain Supported NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA039460: , HPA052272: AB_2681781" "unprognostic (8.92e-3)" "unprognostic (3.23e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (4.76e-6)" "unprognostic (1.00e-1)" "unprognostic (3.74e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (2.01e-3)" "unprognostic (1.38e-1)" "unprognostic (4.19e-3)" "unprognostic (2.44e-2)" "unprognostic (3.99e-2)" "unprognostic (1.19e-2)" "unprognostic (1.17e-1)" "unprognostic (2.56e-1)" "unprognostic (3.00e-1)" "unprognostic (5.55e-2)" 8.2 5.3 20.0 38.5 18.6 26.0 81.8 48.2 18.9 13.6 0.6 39.3 16.7 16.4 8.7 26.6 15.5 16.6 44.6 15.3 42.3 20.3 6.4 13.2 64.4 44.1 25.4 9.9 23.8 78.7 19.3 22.5 34.6 29.5 38.5 79.0 20.5 35.6 90.7 30.5 22.9 27.8 48.4 31.9 21.3 1.1 26.8 59.5 42.5 82.4 54.4 23.4 11.2 59.7 77.6 79.2 28.2 104.9 12.4 4.5 142.8 60.6 98.2 27.3 42.7 136.6 74.9 176.3 113.0 74.7 83.6 116.5 94.8 124.5 50.4 109.6 49.8 12.3 127.4 51.2 108.3 126.1 4.5 21.7 186.7 8.2 325.1 67.5 61.6 112.0 65.2 144.2 86.5 96.5 112.7 22.0 104.1 0.1 122.7 99.8 6.9 124.6 105.4 109.8 111.6 77.2 126.2 152.9 71.7 108.0 88.9 91.1 129.8 21.2 19.7 0.6 62.7 136.2 126.5 386.1 67.9 242.2 18.6 1.0 0.8 26.3 51.8 0.2 71.0 50.4 54.1 61.0 34.9 57.8 62.6 57.1 2.4 68.3 0.4 44.3 63.5 46.4 20.0 18.6 48.2 18.9 15.3 42.3 44.1 25.4 34.6 48.4 26.8 59.7 10.3 35.3 44.7 75.4 150.0 97.8 73.8 103.8 30.1 443.5 136.5 64.8 207.5 38.6 61.8 213.3 141.8 106.9 216.3 99.3 3.9 56.3 0.2 78.1 9.8 26.7 40.6 25.6 104.7 46.4 79.3 14.6 19.4 123.7 3.8 30.9 5.7 6.1 12.2 8.4 157.8 73.6 79.3 12.9 76.1 0.3 2.1 23.3 26.6 30.9 13.6 51.4 107.1 94.5 59.7 53.5 52.8 0.7 138.8 66.5 23.6 1.1 29.7 54.2 0.0 62.9 34.5 0.1 0.4 70.3 122.7 185.7 167.9 1.6 93.6 75.4 SLC38A10 "MGC15523, PP1744" ENSG00000157637 "Solute carrier family 38 member 10" Q9HBR0 17 81244811-81295547 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021374, HPA023161, HPA024631" Enhanced Enhanced "Golgi apparatus" NA NA 70000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA021374: AB_1853858, HPA023161: AB_2190402, HPA024631: AB_1853860" "unprognostic (2.18e-2)" "unprognostic (1.54e-1)" "unprognostic (7.40e-2)" "unprognostic (3.00e-3)" "unprognostic (2.06e-2)" "unprognostic (1.69e-1)" "unprognostic (2.12e-1)" "unprognostic (2.63e-1)" "unprognostic (1.84e-1)" "unprognostic (1.92e-2)" "prognostic favorable (2.92e-4)" "unprognostic (8.39e-2)" "prognostic unfavorable (5.34e-7)" "unprognostic (6.55e-2)" "unprognostic (3.15e-1)" "unprognostic (1.31e-1)" "unprognostic (2.45e-1)" 37.6 37.0 12.7 23.4 14.0 30.8 31.2 12.7 16.1 33.0 14.7 31.7 31.8 35.3 17.3 24.0 31.7 25.8 36.8 10.5 13.8 31.6 75.2 31.4 21.4 21.5 14.9 37.7 91.4 15.6 62.1 24.6 15.7 34.2 9.5 4.4 51.1 20.8 20.0 25.2 34.7 15.4 13.3 43.8 38.8 30.5 16.6 12.9 41.3 6.3 10.6 37.6 26.8 19.4 45.2 77.5 13.3 70.2 49.8 23.3 77.6 53.7 48.2 32.5 38.2 36.1 73.0 34.4 59.2 37.3 36.0 53.0 13.5 27.1 12.0 34.7 40.0 34.6 28.5 61.2 44.4 34.1 78.4 40.7 19.7 29.2 18.9 26.2 62.2 24.5 26.3 51.3 24.6 56.5 21.0 59.4 12.9 41.3 37.6 33.8 27.8 34.8 22.2 42.3 25.7 65.7 43.2 26.9 59.2 18.3 38.1 70.0 61.9 52.2 29.9 38.9 29.4 44.6 21.4 20.0 30.9 51.8 54.5 12.7 10.6 18.6 7.4 11.9 8.7 6.2 7.1 9.1 6.2 7.0 4.8 5.4 8.0 4.6 15.9 9.8 5.6 9.5 12.7 14.0 12.7 16.1 10.5 13.8 21.5 14.9 15.7 13.3 16.6 19.4 24.4 25.6 35.6 25.8 28.6 8.3 12.3 21.9 13.6 10.9 25.3 18.0 19.3 31.5 24.6 11.0 18.8 61.0 29.8 66.4 5.9 31.9 25.4 17.3 13.7 22.4 45.0 22.3 12.3 26.9 62.4 35.9 44.9 32.8 15.2 64.6 27.5 79.2 49.3 25.2 14.3 58.8 12.2 40.6 15.1 75.6 32.9 35.7 14.2 28.1 29.1 27.7 23.7 9.0 20.5 25.1 53.1 27.4 96.5 16.0 59.1 23.9 21.4 9.1 32.9 17.0 21.2 19.7 22.8 11.8 7.2 62.5 25.0 39.9 48.2 11.4 SLC39A1 "ZIP1, ZIRTL" ENSG00000143570 "Solute carrier family 39 member 1" Q9NY26 1 153959099-153968184 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 342.4;Ductal cells: 219.3;Extravillous trophoblasts: 297.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (6.27e-2)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.13e-1)" "unprognostic (2.63e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (5.26e-5)" "prognostic unfavorable (4.12e-7)" "unprognostic (2.36e-2)" "unprognostic (2.62e-2)" "unprognostic (4.41e-1)" "unprognostic (4.83e-3)" "unprognostic (1.93e-1)" "unprognostic (5.10e-3)" "unprognostic (2.54e-2)" "unprognostic (1.23e-1)" "unprognostic (5.51e-2)" "unprognostic (6.68e-2)" 67.1 73.2 39.0 48.6 42.7 10.6 62.5 41.9 41.6 56.7 45.1 53.8 36.2 59.9 33.8 50.1 53.8 55.2 62.1 37.4 42.1 77.0 76.7 87.4 35.3 51.7 43.8 54.7 48.9 65.5 30.5 94.9 44.5 56.8 38.2 10.2 51.9 46.4 45.4 65.3 48.4 49.9 44.8 56.0 59.0 20.6 45.3 26.1 56.6 38.7 36.2 60.5 48.3 43.7 122.5 138.3 111.5 93.7 103.4 105.2 244.2 76.8 188.7 128.1 140.2 203.6 303.0 47.2 240.0 108.5 106.8 266.8 114.8 118.9 72.6 146.5 92.5 64.3 138.9 92.9 118.3 49.4 71.1 128.6 108.9 101.1 99.8 119.2 92.7 54.2 62.6 53.5 104.5 251.5 51.0 64.1 158.6 253.4 107.2 56.3 96.3 57.2 202.7 88.1 49.3 116.0 143.6 363.4 136.4 142.9 195.7 104.8 81.6 114.7 105.6 84.3 113.6 64.8 87.1 61.8 82.0 38.8 157.0 16.6 68.1 20.3 33.9 78.9 21.1 34.8 25.1 25.6 56.0 39.8 27.2 24.7 67.3 30.6 95.5 51.3 26.9 58.1 39.0 42.7 41.9 41.6 37.4 42.1 51.7 43.8 44.5 44.8 45.3 43.7 71.0 9.6 3.3 7.5 21.9 56.5 97.7 105.8 59.2 7.7 56.7 50.2 13.5 61.5 39.0 53.3 2.1 342.4 35.6 33.9 13.7 219.3 1.0 21.4 38.9 70.1 19.2 17.4 1.8 113.8 297.2 60.6 17.3 35.7 36.8 22.2 49.6 25.6 116.5 18.5 3.1 28.4 40.7 63.6 43.4 3.4 48.4 57.8 48.0 8.4 78.6 36.5 28.8 6.0 6.6 127.8 33.9 62.1 19.8 127.4 49.8 39.6 19.2 6.9 46.0 41.3 55.2 31.3 35.7 26.1 53.4 153.1 21.3 42.5 32.3 74.0 SLC39A10 "DKFZp564L2123, FLJ90515, KIAA1265" ENSG00000196950 "Solute carrier family 39 member 10" Q9ULF5 2 195575977-195737702 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 48.4" "Cell type enhanced" "Detected in all" "Excitatory neurons: 170.8;Microglial cells: 362.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036512, HPA036513, HPA066087" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 250000 "Cluster 6: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036512: AB_2675165, HPA036513: AB_10670801, HPA066087: AB_2685613" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (5.33e-2)" "unprognostic (1.33e-3)" "prognostic favorable (1.46e-5)" "unprognostic (7.40e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (2.10e-2)" "unprognostic (8.73e-2)" "unprognostic (2.84e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (8.46e-2)" "unprognostic (9.71e-2)" "unprognostic (1.34e-2)" "unprognostic (3.68e-1)" "unprognostic (2.47e-2)" "unprognostic (6.89e-2)" 8.2 9.7 7.9 6.3 7.4 4.6 7.1 0.0 21.0 10.8 0.0 4.3 3.9 11.0 3.7 3.6 9.5 8.8 4.3 15.8 0.0 8.7 2.0 7.4 8.3 0.1 0.4 7.9 4.8 5.2 1.1 12.8 1.7 19.1 4.2 5.1 3.7 6.7 1.3 7.0 4.0 7.7 1.4 18.3 5.0 9.3 9.9 10.6 48.4 3.1 7.6 6.3 2.1 5.8 7.3 27.1 46.8 13.0 9.5 21.1 24.3 34.8 16.4 16.1 8.1 38.4 26.4 10.4 51.3 19.6 12.4 10.4 28.6 31.6 19.9 5.4 21.8 11.7 37.1 34.0 10.8 45.4 4.9 12.9 5.1 17.7 20.2 56.9 37.3 10.5 34.9 14.3 26.7 7.3 12.7 14.0 53.8 44.1 18.8 28.9 16.6 27.0 74.8 12.7 17.5 24.7 34.4 65.1 18.7 81.2 11.2 26.5 36.1 28.7 33.6 19.0 18.7 4.6 3.7 6.3 24.5 19.9 29.9 41.5 4.7 3.7 7.5 4.4 6.1 12.3 6.8 6.7 6.4 15.8 6.0 7.8 0.8 21.7 3.3 32.8 7.6 2.6 7.9 7.4 0.0 21.0 15.8 0.0 0.1 0.4 1.7 1.4 9.9 5.8 72.1 3.2 12.8 40.8 42.0 25.6 12.1 51.3 13.1 23.0 16.9 23.1 7.6 5.7 33.2 36.8 8.4 49.3 60.2 4.3 1.9 17.7 28.5 13.2 48.7 75.4 15.6 26.9 170.8 11.3 66.0 35.3 11.2 16.5 13.3 25.7 26.4 2.8 24.5 8.4 78.3 5.9 26.4 20.7 27.1 16.0 19.0 31.8 7.2 362.6 16.2 17.0 20.6 49.3 49.5 24.3 2.8 18.8 21.3 20.1 4.5 14.7 9.5 20.0 13.1 41.9 29.1 61.3 33.6 7.5 20.5 23.4 35.4 30.8 6.2 7.8 SLC39A11 C17orf26 ENSG00000133195 "Solute carrier family 39 member 11" Q8N1S5 17 72645949-73092712 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 205.3;Excitatory neurons: 107.7;Oligodendrocytes: 360.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 217.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021455 Approved Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA021455: AB_2670710" "unprognostic (2.29e-2)" "unprognostic (2.75e-1)" "unprognostic (1.25e-1)" "unprognostic (2.19e-1)" "unprognostic (1.61e-1)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.44e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-1)" "unprognostic (3.45e-3)" "unprognostic (2.30e-1)" "unprognostic (1.57e-3)" "unprognostic (5.26e-2)" "unprognostic (1.17e-1)" "unprognostic (4.96e-3)" "unprognostic (3.85e-2)" 12.6 7.8 14.0 10.8 27.8 21.2 17.4 22.5 17.2 14.9 9.5 24.0 20.3 5.5 15.7 15.5 9.1 11.0 4.9 14.1 17.9 13.4 39.4 10.9 8.8 25.7 23.7 3.4 29.3 4.7 2.9 8.7 24.0 7.7 24.1 2.3 30.3 8.0 4.5 14.2 22.8 7.3 16.9 7.9 48.2 6.8 23.9 5.5 36.1 3.5 12.4 12.5 9.3 35.3 20.5 36.8 4.3 17.2 30.7 24.8 24.4 21.6 19.0 9.7 13.0 13.7 90.7 25.4 21.5 22.1 15.4 17.2 6.2 10.9 14.8 27.6 12.8 23.8 9.9 16.3 18.3 25.4 217.5 21.2 20.3 20.1 11.6 10.6 10.1 13.1 12.6 31.0 12.4 28.9 16.3 55.1 3.5 62.4 15.6 10.9 16.3 21.5 16.0 20.9 10.2 13.8 11.6 84.7 12.7 16.8 58.4 34.9 8.5 19.0 17.7 16.3 13.4 24.9 12.2 17.9 30.8 50.6 11.1 19.3 39.9 26.0 16.7 40.4 10.9 16.7 12.5 12.5 37.9 9.8 8.8 12.1 6.6 22.6 33.1 26.8 17.1 18.1 14.0 27.8 22.5 17.2 14.1 17.9 25.7 23.7 24.0 16.9 23.9 35.3 4.9 0.0 6.3 205.3 7.6 4.5 5.3 5.6 10.2 2.6 13.7 5.5 2.3 4.3 8.6 3.7 0.0 5.6 6.9 15.8 0.0 9.4 18.5 5.6 3.6 4.0 8.4 9.9 107.7 14.1 17.4 4.7 29.0 9.5 29.9 7.9 3.6 30.1 26.3 5.0 32.1 79.0 10.2 21.0 5.6 66.7 4.1 14.4 10.6 64.6 19.6 4.1 8.2 22.6 360.3 9.1 20.5 3.4 15.1 6.0 24.8 11.5 7.8 1.6 13.1 2.6 7.1 2.0 2.9 10.3 4.4 4.9 5.4 4.4 18.3 7.5 SLC39A14 "KIAA0062, NET34, ZIP14" ENSG00000104635 "Solute carrier family 39 member 14" Q15043 8 22367278-22434129 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 551.3;pancreas: 252.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 266.7;Hepatocytes: 611.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ hTERT+: 321.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016508, HPA056732" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA 1100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Golgi apparatus, Plasma membrane" "HPA016508: AB_1857148, HPA056732: " "unprognostic (1.67e-1)" "unprognostic (6.67e-3)" "prognostic favorable (5.00e-5)" "unprognostic (9.83e-3)" "unprognostic (9.21e-3)" "unprognostic (8.99e-3)" "unprognostic (1.99e-1)" "unprognostic (2.91e-2)" "unprognostic (4.95e-2)" "unprognostic (5.66e-2)" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.79e-7)" "unprognostic (4.88e-2)" "unprognostic (8.73e-2)" "unprognostic (1.63e-2)" "unprognostic (1.11e-3)" 63.5 72.4 13.0 35.5 11.0 1.4 39.8 11.9 13.1 17.3 39.7 48.2 142.2 30.2 6.2 11.6 25.9 32.0 76.7 14.5 22.9 30.8 551.3 23.9 7.6 43.0 30.4 27.7 252.7 12.9 21.5 19.0 25.7 22.3 50.3 18.6 21.8 18.7 43.0 20.0 84.9 33.0 13.3 8.1 80.5 26.5 25.3 6.0 87.7 17.4 6.9 56.0 14.5 14.8 51.8 68.3 18.4 37.6 65.1 54.7 40.1 72.8 321.0 111.3 173.5 226.9 47.9 51.1 39.9 86.1 288.9 55.6 92.8 91.1 181.9 53.1 49.2 40.8 51.0 230.7 154.3 28.5 43.2 58.4 72.6 198.0 136.9 56.3 50.5 36.5 36.2 51.2 57.3 24.0 43.4 18.2 113.4 81.9 49.8 60.1 34.9 110.8 40.8 22.3 31.3 48.7 74.3 31.3 151.4 39.7 25.1 39.4 28.0 137.3 69.2 87.4 75.7 29.2 28.7 66.9 194.3 37.7 81.9 0.0 0.4 2.1 6.7 0.1 7.2 4.0 3.8 5.0 1.5 1.9 4.3 5.9 0.1 2.7 0.1 0.7 3.4 3.4 13.0 11.0 11.9 13.1 14.5 22.9 43.0 30.4 25.7 13.3 25.3 14.8 12.4 3.2 7.7 11.4 9.1 33.3 11.5 10.8 18.8 7.8 20.3 16.6 66.6 41.5 3.8 7.3 2.1 0.4 3.6 91.6 1.9 47.6 0.5 136.1 58.3 32.2 33.4 10.5 26.2 74.7 2.7 58.8 47.9 266.7 0.0 20.8 29.6 611.4 1.8 48.8 24.6 60.6 6.1 15.4 25.8 3.2 23.9 2.9 44.4 6.5 2.7 5.2 2.1 9.0 3.9 47.3 39.1 41.8 13.5 26.5 75.6 24.6 1.1 8.2 0.0 47.1 32.2 0.7 3.0 4.1 21.0 0.5 7.4 14.7 43.5 9.4 SLC39A4 "AEZ, AWMS2, ZIP4" ENSG00000147804 "Solute carrier family 39 member 4" Q6P5W5 8 144409742-144416844 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 88.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 406.4;Proximal tubular cells: 230.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "CAPAN-2: 36.4;Hep G2: 97.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.59e-1)" "unprognostic (2.35e-3)" "unprognostic (9.16e-2)" "unprognostic (3.84e-2)" "unprognostic (5.63e-3)" "unprognostic (1.46e-1)" "unprognostic (5.40e-2)" "unprognostic (1.54e-1)" "unprognostic (1.61e-1)" "unprognostic (3.28e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "prognostic favorable (9.04e-4)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (9.04e-3)" "unprognostic (1.87e-1)" 0.1 0.2 0.1 1.4 0.2 0.5 0.3 0.0 0.7 0.7 0.0 33.1 88.1 0.4 0.1 0.2 0.9 0.5 0.0 0.2 0.0 18.4 1.3 3.1 0.1 0.0 0.0 3.3 1.4 0.0 0.2 1.0 0.0 1.3 0.5 0.0 1.2 0.3 0.0 0.5 74.9 0.1 0.0 0.7 2.9 1.3 0.0 0.0 3.9 0.0 0.0 0.6 0.6 0.0 2.3 0.2 0.0 0.1 0.0 0.0 2.5 0.1 0.0 0.0 0.0 2.1 36.4 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 6.4 0.8 1.6 0.6 97.4 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.5 2.2 0.0 1.7 0.0 0.4 0.1 0.5 0.1 0.4 0.0 1.1 0.0 0.4 0.9 1.9 0.2 0.4 0.1 0.4 1.7 0.1 0.0 0.1 0.2 0.0 0.0 0.9 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 19.2 24.8 0.3 21.3 18.7 36.6 46.9 38.7 0.2 45.0 50.3 7.4 20.0 24.1 42.3 0.0 17.0 15.4 112.8 50.9 40.0 1.4 41.8 12.9 10.9 42.6 26.3 1.0 42.9 69.7 16.8 29.6 51.9 37.4 8.5 8.9 27.4 32.1 3.3 0.2 95.0 30.5 18.2 21.0 2.0 8.1 23.5 21.4 0.0 25.9 11.3 23.7 0.0 0.1 75.6 135.0 6.4 31.9 60.8 406.4 230.3 26.9 1.0 6.6 7.5 11.1 2.9 33.1 46.4 30.0 11.2 15.4 23.2 98.2 46.3 SLC39A5 ENSG00000139540 "Solute carrier family 39 member 5" Q6ZMH5 12 56230049-56237846 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "intestine: 237.4;kidney: 110.0;liver: 171.1;pancreas: 306.8" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 798.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 30.6;liver cancer: 36.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 53 "CACO-2: 39.9;Hep G2: 58.5" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" HPA018423 Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Vesicles Nucleoplasm "HPA018423: AB_1857154" "unprognostic (5.94e-3)" "unprognostic (8.29e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-7)" "unprognostic (1.73e-1)" "unprognostic (7.79e-2)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.93e-3)" "prognostic favorable (5.05e-4)" "unprognostic (2.75e-1)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.96e-4)" 0.3 0.1 0.2 5.5 0.2 0.1 0.3 0.5 0.4 0.3 0.2 73.7 237.4 0.4 0.0 0.1 0.3 6.5 0.2 0.1 0.1 110.0 171.1 0.2 0.4 0.2 0.1 0.4 306.8 0.0 0.2 0.1 0.1 0.3 45.9 6.4 0.1 0.3 0.1 0.3 219.0 2.6 0.1 0.3 1.4 0.2 0.1 0.0 0.3 0.2 0.0 0.2 0.2 0.1 0.0 0.3 0.1 0.2 0.2 0.3 0.5 0.0 0.0 0.1 0.0 39.9 0.4 0.1 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.6 0.1 0.2 0.2 58.5 0.2 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.2 0.0 0.8 0.0 0.9 0.1 0.2 0.2 0.3 0.5 0.1 0.3 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.4 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.4 0.6 0.1 0.0 0.0 0.9 0.1 0.3 0.2 15.7 0.0 3.7 116.7 0.0 0.0 171.9 19.6 0.3 0.6 0.0 0.1 0.2 25.3 2.7 0.2 20.6 0.0 0.1 0.0 0.0 0.0 0.0 2.2 138.9 0.1 0.0 0.2 112.7 0.0 1.6 1.2 1.4 0.0 1.3 0.0 0.0 0.6 0.6 0.0 0.0 0.1 7.4 192.8 0.0 0.0 0.1 798.4 169.9 0.0 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.8 0.0 168.7 0.0 SLC3A1 "ATR1, CSNU1, D2H, NBAT, RBAT" ENSG00000138079 "Solute carrier family 3 member 1" Q07837 2 44275458-44321494 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cystinuria, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 136.2;kidney: 649.3;pancreas: 217.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Glandular and luminal cells: 128.9;Proximal enterocytes: 258.9;Proximal tubular cells: 363.0" "Cancer enriched" "Detected in many" 7 "renal cancer: 61.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 22 "RPTEC TERT1: 106.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038360, HPA071102" Enhanced Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Nuclear bodies" "HPA038360: AB_2675975, HPA071102: AB_2732171" "unprognostic (1.67e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-2)" "unprognostic (6.14e-2)" "unprognostic (9.45e-2)" "unprognostic (2.76e-2)" "unprognostic (1.34e-1)" "unprognostic (3.90e-1)" "unprognostic (8.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.17e-1)" "prognostic favorable (3.67e-7)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (3.77e-1)" "unprognostic (1.58e-4)" 0.5 0.3 1.2 1.1 1.7 0.6 0.4 6.8 3.4 1.0 0.1 22.4 113.9 1.4 1.9 0.2 0.6 51.5 0.4 1.6 1.3 649.3 36.6 0.4 0.4 0.6 0.6 0.5 217.5 0.0 0.5 0.1 0.7 1.0 22.7 3.5 0.3 0.3 1.0 0.6 136.2 0.5 0.0 0.5 0.9 1.7 1.0 0.0 0.4 0.1 0.1 0.3 0.3 1.7 0.0 1.0 0.0 0.2 0.2 0.1 0.3 0.1 0.0 0.0 0.1 4.9 0.0 0.1 4.3 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.4 0.2 0.0 0.0 0.4 0.1 1.2 0.5 0.1 0.1 0.2 106.1 0.0 0.2 0.2 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.2 0.3 0.2 0.1 0.4 0.2 0.3 0.1 0.3 0.2 0.4 0.3 0.3 0.7 0.3 0.4 0.5 0.6 0.3 0.1 1.0 0.6 0.7 0.4 0.4 0.1 0.3 0.2 0.1 1.2 1.7 6.8 3.4 1.6 1.3 0.6 0.6 0.7 0.0 1.0 1.7 0.2 3.2 1.5 0.3 6.1 0.0 0.3 0.0 0.0 12.1 0.2 0.0 0.4 74.4 0.0 42.3 10.4 0.1 0.8 18.2 62.6 37.0 12.4 62.2 14.4 0.6 0.0 0.0 9.1 13.8 0.0 0.9 1.1 128.9 0.0 0.1 0.4 4.6 0.1 21.9 9.0 8.4 0.0 0.0 0.0 8.5 1.2 3.2 0.0 1.0 1.6 1.0 1.0 3.0 3.7 4.8 18.6 0.4 1.5 1.1 258.9 363.0 0.0 11.2 0.0 2.6 1.2 0.8 0.4 0.7 0.1 0.1 2.8 0.2 15.7 1.2 SLC43A3 "DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1" ENSG00000134802 "Solute carrier family 43 member 3" Q8NBI5 11 57406954-57427580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 146.9" "Cell type enhanced" "Detected in many" "Ductal cells: 75.5;granulocytes: 67.0;Hofbauer cells: 73.7;Langerhans cells: 74.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 105.7;intermediate monocyte: 127.0;myeloid DC: 85.8;non-classical monocyte: 146.3;plasmacytoid DC: 85.7" "Group enriched" "Detected in all" 4 "dendritic cells: 85.8;monocytes: 146.3" "Cell line enhanced" "Detected in many" "HL-60: 513.8;HMC-1: 428.4;RPMI-8226: 570.9;WM-115: 532.1" "Region enhanced" "Detected in many" "olfactory bulb: 10.3" "Low region specificity" "Detected in all" "HPA030551, HPA077244" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Plasma membrane" "HPA030551: AB_10604094, HPA077244: AB_2732335" "unprognostic (2.64e-1)" "unprognostic (7.63e-2)" "unprognostic (9.67e-3)" "unprognostic (7.41e-3)" "unprognostic (6.59e-3)" "unprognostic (5.30e-3)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (5.73e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (3.97e-13)" "unprognostic (8.16e-2)" "unprognostic (1.77e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-1)" 61.4 16.8 5.2 34.8 5.9 58.0 50.3 5.9 7.3 40.2 6.8 23.7 8.3 28.1 4.5 34.8 30.0 28.5 34.8 5.5 7.1 15.9 146.9 46.9 26.5 6.7 6.4 24.3 13.7 3.9 4.9 14.3 7.3 14.4 11.8 0.9 35.2 7.5 15.6 34.6 20.6 25.5 6.3 20.8 20.1 4.7 11.1 23.2 76.3 13.3 28.9 30.7 28.2 8.5 289.2 0.0 16.0 0.4 52.9 76.9 0.7 22.0 93.0 31.6 54.1 0.0 61.4 165.0 9.8 52.0 16.3 161.8 47.0 28.8 63.3 1.0 0.2 257.3 93.0 0.0 106.6 513.8 428.4 231.7 0.9 306.5 3.5 22.9 89.7 75.0 299.8 154.4 123.7 0.6 108.6 328.2 24.3 0.0 5.3 221.8 3.3 570.9 76.1 0.0 38.0 0.0 62.2 1.4 263.5 1.5 24.1 77.3 48.1 1.5 81.4 209.2 62.5 0.3 0.9 41.3 187.3 183.2 532.1 15.2 105.7 23.4 19.6 127.0 22.2 9.6 13.5 26.8 85.8 7.1 10.4 10.5 9.0 3.9 146.3 85.7 26.5 60.7 5.2 5.9 5.9 7.3 5.5 7.1 6.7 6.4 7.3 6.3 11.1 8.5 19.8 16.0 49.1 1.6 6.1 46.8 7.4 30.8 48.3 0.5 8.0 14.2 3.7 28.6 26.1 1.8 0.0 0.6 11.9 0.3 0.0 75.5 1.0 1.0 3.1 33.0 0.0 38.3 0.1 6.4 5.0 33.4 2.0 3.0 67.0 2.9 14.3 61.7 73.7 0.0 0.2 0.6 16.2 21.0 74.6 1.7 9.9 47.0 30.2 8.4 10.2 0.6 3.1 8.5 0.8 9.4 0.5 12.4 22.5 14.5 0.0 0.1 4.9 0.1 65.7 15.5 22.0 0.7 1.1 13.6 17.6 0.8 11.8 12.3 1.2 3.0 SLC51A OSTalpha ENSG00000163959 "Solute carrier family 51 subunit alpha" Q86UW1 3 196211487-196243178 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "intestine: 64.5;liver: 71.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 49.1;Leydig cells: 61.5;Peritubular cells: 101.5;Proximal enterocytes: 271.8;Sertoli cells: 144.7" "Cancer enriched" "Detected in many" 7 "liver cancer: 15.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 3.9;U-266/84: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045488 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA045488: " "unprognostic (1.63e-2)" "unprognostic (1.27e-3)" "unprognostic (2.80e-1)" "unprognostic (7.66e-2)" "unprognostic (5.16e-2)" "unprognostic (2.40e-2)" "prognostic favorable (7.54e-4)" "unprognostic (5.02e-2)" "unprognostic (1.07e-1)" "unprognostic (5.98e-3)" "unprognostic (5.41e-2)" "unprognostic (2.90e-2)" "unprognostic (2.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-5)" 1.3 5.2 0.2 1.3 0.2 5.9 1.2 0.1 0.7 2.0 0.0 11.3 30.5 0.8 0.8 1.4 1.6 0.6 1.3 0.2 0.4 5.5 71.3 2.0 0.6 0.2 0.1 1.4 0.9 2.7 1.2 0.2 0.3 1.1 0.7 0.7 1.2 0.0 1.6 2.5 64.5 0.2 0.0 1.8 0.9 4.1 0.7 0.1 1.5 0.0 0.5 1.0 1.8 0.5 0.5 0.7 0.6 0.7 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.3 0.2 0.0 0.8 0.5 0.0 0.4 0.0 0.0 0.0 0.3 1.3 0.5 0.4 0.8 0.1 0.6 0.6 0.1 0.0 0.0 0.0 0.6 0.1 0.1 0.1 1.5 0.0 0.3 0.0 0.6 0.0 0.1 0.9 3.9 0.0 0.2 0.0 0.4 0.1 0.2 0.2 1.4 0.1 0.1 1.1 0.2 0.2 0.7 0.3 0.6 0.4 1.5 2.0 0.2 0.5 0.2 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.7 0.2 0.4 0.2 0.1 0.3 0.0 0.7 0.5 1.1 0.0 0.5 0.3 1.0 3.3 2.5 10.9 0.0 0.5 0.6 0.3 4.1 1.5 18.2 0.0 4.2 0.7 3.0 43.5 3.9 0.2 20.7 2.7 1.6 1.6 0.0 2.7 1.0 0.2 0.4 2.4 0.0 1.6 0.0 2.3 3.9 49.1 0.6 1.7 0.7 8.4 22.4 4.4 7.3 12.9 61.5 1.3 3.6 1.0 0.8 0.4 1.0 0.5 0.2 0.1 12.1 101.5 0.8 1.5 271.8 11.5 18.0 1.1 144.7 2.3 2.6 2.4 1.3 0.0 2.6 1.0 3.0 13.6 11.8 2.8 SLC5A6 SMVT ENSG00000138074 "Solute carrier family 5 member 6" Q9Y289 2 27199587-27212958 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 119.1;Extravillous trophoblasts: 111.7;Hepatocytes: 67.7;Syncytiotrophoblasts: 227.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 310.9;SK-BR-3: 337.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036958 Approved Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA036958: AB_10672343" "unprognostic (5.85e-2)" "unprognostic (8.32e-3)" "unprognostic (1.38e-1)" "unprognostic (2.61e-3)" "unprognostic (9.38e-2)" "unprognostic (7.14e-2)" "unprognostic (3.20e-3)" "unprognostic (7.92e-2)" "unprognostic (6.96e-2)" "unprognostic (9.80e-2)" "unprognostic (2.05e-2)" "unprognostic (7.46e-2)" "prognostic unfavorable (3.60e-7)" "unprognostic (2.40e-3)" "unprognostic (1.20e-2)" "unprognostic (4.56e-3)" "unprognostic (4.18e-2)" 42.4 8.6 27.5 14.2 25.2 18.1 31.5 24.0 30.6 9.4 46.2 13.0 20.9 14.3 67.4 10.9 11.5 7.5 7.7 23.4 23.9 8.5 104.0 7.9 13.8 24.0 24.4 10.2 11.6 9.8 8.0 39.1 25.9 9.3 12.7 6.4 12.5 11.1 17.0 10.0 15.3 9.7 23.9 9.1 10.1 23.4 30.6 11.6 8.0 8.8 26.5 11.3 8.8 21.9 78.9 79.6 49.9 66.1 45.4 16.5 310.9 28.1 19.1 41.8 28.7 118.8 27.0 54.2 41.3 15.4 44.7 42.8 108.3 32.4 29.1 42.2 63.5 96.6 34.9 184.4 53.8 125.1 47.8 57.1 27.1 51.4 39.7 11.1 38.2 43.3 143.6 21.1 27.0 161.0 42.7 60.4 144.8 90.1 29.0 70.7 58.7 78.2 24.0 74.5 42.0 61.7 30.3 337.1 40.1 48.6 74.9 26.0 17.5 45.3 62.5 27.9 76.1 35.7 88.6 84.7 24.5 86.1 65.2 0.1 5.9 1.8 7.4 6.6 8.9 5.8 7.0 7.0 8.7 5.3 7.1 8.6 0.3 6.3 8.9 8.9 7.6 5.8 27.5 25.2 24.0 30.6 23.4 23.9 24.0 24.4 25.9 23.9 30.6 21.9 2.5 0.0 4.4 7.8 13.4 8.0 8.6 3.8 7.4 5.3 41.9 31.9 6.8 8.6 3.1 7.3 4.2 119.1 12.5 6.7 1.9 9.8 15.1 3.9 7.4 6.2 5.4 12.6 7.2 8.2 111.7 6.0 5.6 6.9 0.0 18.1 7.1 67.7 21.8 11.8 9.0 9.2 4.1 9.1 6.0 32.0 7.2 6.6 0.0 29.0 47.9 2.5 6.2 6.6 5.0 7.0 4.3 13.9 10.0 14.1 11.7 3.9 2.9 3.1 13.1 5.5 5.2 35.1 21.5 7.6 6.3 227.9 8.6 9.4 15.2 7.8 SLC6A9 GLYT1 ENSG00000196517 "Solute carrier family 6 member 9" P48067 1 43991500-44031467 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.4;skin 1: 46.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.7;Distal enterocytes: 17.8;Erythroid cells: 33.1;Ionocytes: 20.3" "Cancer enhanced" "Detected in all" "glioma: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 62.3;hTCEpi: 106.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013977 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA013977: AB_1849835" "unprognostic (2.73e-2)" "unprognostic (1.92e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (5.98e-2)" "unprognostic (6.83e-3)" "unprognostic (3.06e-2)" "unprognostic (9.72e-2)" "unprognostic (1.85e-2)" "unprognostic (3.52e-2)" "unprognostic (1.41e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (5.93e-4)" "unprognostic (5.36e-3)" "unprognostic (1.59e-1)" "unprognostic (2.53e-1)" "unprognostic (1.20e-2)" 3.9 31.0 21.7 4.9 45.5 10.8 4.6 53.2 24.2 12.1 6.3 11.0 2.3 7.4 1.1 23.1 9.5 4.8 2.1 16.1 31.3 4.3 2.3 11.6 1.1 66.3 43.5 2.9 8.2 2.8 1.7 1.4 63.6 3.9 6.3 17.2 11.5 5.5 1.1 46.6 6.0 9.1 45.6 1.9 7.4 1.1 45.9 1.4 5.3 0.6 4.3 12.3 25.1 72.4 19.7 13.7 7.1 18.0 11.2 3.7 15.6 14.7 41.0 24.3 30.1 4.8 7.5 0.3 1.6 42.9 0.0 62.3 11.0 12.5 5.0 0.1 1.8 17.1 33.9 5.8 50.3 3.8 0.7 11.3 106.6 11.9 28.5 15.3 0.6 12.3 13.0 48.5 1.0 10.4 2.9 0.1 5.4 7.4 19.1 2.2 0.0 22.9 2.3 2.2 4.4 4.2 7.4 35.3 7.0 1.7 9.1 10.3 0.2 2.8 11.0 2.4 8.0 53.1 39.2 4.4 9.2 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 45.5 53.2 24.2 16.1 31.3 66.3 43.5 63.6 45.6 45.9 72.4 1.5 0.0 2.0 5.9 1.1 7.5 0.9 3.2 8.0 30.7 2.2 0.9 0.7 4.3 2.2 1.8 16.7 0.5 0.5 17.8 0.0 3.7 5.9 4.8 0.4 0.7 0.0 33.1 2.2 8.9 1.0 0.9 1.5 2.7 0.0 0.0 0.0 0.3 0.3 1.7 1.5 2.7 20.3 0.0 1.0 0.8 1.5 0.1 3.6 0.0 1.0 1.2 0.0 3.0 16.4 4.2 3.0 1.5 1.3 2.0 9.1 1.1 12.5 11.1 6.6 0.1 10.0 0.1 0.4 8.9 12.9 0.5 0.3 1.2 2.6 3.2 SLC8A1 NCX1 ENSG00000183023 "Solute carrier family 8 member A1" P32418 2 40097270-40611053 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 117.5" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 743.1;Excitatory neurons: 1267.5;Inhibitory neurons: 631.3;Microglial cells: 574.3;Oligodendrocyte precursor cells: 753.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.2" "Group enriched" "Detected in many" 6 "granulocytes: 44.2;monocytes: 11.5" "Cell line enhanced" "Detected in many" "BJ: 28.9;fHDF/TERT166: 70.4;hTERT-HME1: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022694, HPA070007" Uncertain Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane" "CAB022694: , HPA070007: AB_2686227" "unprognostic (2.46e-1)" "unprognostic (1.33e-2)" "unprognostic (1.42e-2)" "unprognostic (7.57e-6)" "unprognostic (1.56e-1)" "unprognostic (3.94e-1)" "unprognostic (2.28e-2)" "unprognostic (4.60e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.66e-2)" "unprognostic (7.04e-3)" "unprognostic (3.93e-2)" "unprognostic (5.46e-2)" "unprognostic (6.77e-2)" 6.1 4.0 25.7 7.2 25.8 2.0 1.6 0.0 28.0 4.7 0.0 9.6 5.0 19.7 5.6 5.9 5.6 6.5 117.5 30.6 11.0 17.5 3.1 5.8 3.3 1.5 19.8 2.5 1.8 0.7 0.8 11.2 0.7 18.8 4.8 5.9 1.0 27.1 0.3 1.5 5.5 23.4 2.7 7.3 3.5 0.7 19.5 2.0 0.8 0.9 1.5 8.9 2.5 24.1 3.0 2.2 2.1 0.2 3.1 6.4 0.0 28.9 11.1 9.4 6.1 0.0 4.7 0.1 2.2 70.4 10.1 1.1 0.5 4.8 9.5 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.5 3.7 0.0 10.8 19.8 4.3 0.7 0.0 0.0 0.4 12.1 0.0 0.9 0.1 1.4 0.3 4.0 7.8 14.8 0.0 3.3 0.4 3.2 0.6 0.0 0.0 0.0 9.7 0.1 0.6 9.8 8.8 0.3 0.0 3.1 1.6 0.0 0.0 1.4 1.7 1.4 0.0 8.3 0.0 0.0 9.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 44.2 0.0 11.5 0.3 0.0 1.1 25.7 25.8 0.0 28.0 30.6 11.0 1.5 19.8 0.7 2.7 19.5 24.1 10.3 3.2 2.8 39.5 3.6 1.3 0.0 0.2 1.2 79.1 0.5 5.8 743.1 2.8 0.6 35.0 4.2 0.5 0.3 0.0 0.0 0.0 1.1 2.3 52.8 15.1 0.0 3.0 1267.5 0.0 1.6 26.6 1.5 3.0 0.0 0.2 12.1 0.3 29.3 0.0 631.3 2.5 0.0 78.0 26.7 1.4 0.0 88.8 1.8 574.3 42.7 32.0 1.0 753.0 20.5 0.1 3.8 8.2 0.7 0.2 24.7 0.5 0.0 7.2 13.1 1.4 46.6 0.2 1.2 0.5 3.1 1.1 1.2 0.7 2.5 0.1 SLC8B1 "FLJ22233, NCKX6, NCLX, SLC24A6" ENSG00000089060 "Solute carrier family 8 member B1" Q6J4K2 12 113298759-113359493 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sensory transduction, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 75.4" "Cell type enhanced" "Detected in many" "Theca cells: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 54.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040668 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "HPA040668: AB_10793861" "prognostic favorable (9.52e-4)" "unprognostic (1.58e-1)" "unprognostic (1.27e-1)" "unprognostic (4.30e-1)" "unprognostic (1.93e-2)" "unprognostic (2.80e-3)" "unprognostic (1.90e-1)" "unprognostic (6.52e-2)" "unprognostic (1.84e-1)" "unprognostic (2.68e-2)" "unprognostic (2.60e-1)" "unprognostic (5.14e-1)" "unprognostic (1.75e-1)" "unprognostic (1.54e-3)" "unprognostic (9.39e-2)" "unprognostic (1.14e-1)" "prognostic favorable (5.02e-4)" 18.5 75.4 7.6 14.8 10.3 17.7 15.1 8.6 8.6 19.3 4.4 15.6 10.6 11.9 7.9 15.8 13.1 11.3 11.0 7.5 8.0 17.2 17.6 20.6 13.8 14.2 9.5 55.5 18.1 7.5 15.3 8.1 10.6 16.9 9.3 1.4 16.9 9.1 10.0 19.4 16.9 6.9 9.3 29.4 12.1 13.6 11.6 18.0 13.1 5.6 9.9 12.7 15.2 11.2 25.3 5.5 3.2 7.0 15.5 10.9 10.6 8.3 23.8 10.6 10.3 5.4 21.1 6.6 18.5 10.8 9.2 20.1 9.8 5.7 5.1 16.3 3.1 13.3 13.1 6.2 25.8 33.9 28.7 11.1 16.9 12.2 5.2 9.1 24.5 24.0 27.7 3.3 6.0 5.9 10.6 27.5 5.7 8.2 14.2 3.9 4.2 8.3 11.4 34.7 0.2 5.4 22.5 45.1 5.4 4.2 8.0 13.1 54.3 7.5 8.8 22.4 5.0 4.5 10.3 5.0 9.6 19.2 6.0 4.1 16.5 32.8 8.0 24.1 10.2 3.3 14.5 7.9 19.1 4.4 28.8 13.5 10.3 6.1 24.8 14.3 19.4 15.8 7.6 10.3 8.6 8.6 7.5 8.0 14.2 9.5 10.6 9.3 11.6 11.2 9.3 12.8 12.6 13.7 5.8 4.5 13.2 8.0 4.6 2.4 8.4 6.5 4.3 8.6 10.9 12.9 10.4 7.8 9.2 30.6 5.9 13.0 1.5 6.0 9.4 9.6 4.9 1.7 7.7 17.4 8.6 13.6 14.3 15.5 21.5 32.4 6.4 12.0 21.6 0.0 3.9 13.3 4.1 21.8 22.6 1.5 24.5 32.4 1.8 22.5 17.8 2.8 5.2 4.0 6.2 22.5 20.7 28.2 3.3 19.1 23.6 3.3 4.5 0.8 32.9 9.9 13.3 1.0 3.9 12.2 7.1 10.7 9.8 96.7 13.3 21.3 SLC9A5 NHE5 ENSG00000135740 "Solute carrier family 9 member A5" Q14940 16 67237683-67272191 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6;lymphoid tissue: 17.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 11.1;Horizontal cells: 16.8;Inhibitory neurons: 12.2;Oligodendrocyte precursor cells: 7.1;Spermatocytes: 17.2;Theca cells: 6.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041004, HPA041329" Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Plasma membrane" "HPA041004: AB_10794433, HPA041329: AB_10794373" "unprognostic (8.90e-2)" "unprognostic (9.70e-2)" "unprognostic (3.39e-3)" "unprognostic (1.37e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-2)" "unprognostic (5.17e-2)" "unprognostic (1.50e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-3)" "unprognostic (4.84e-2)" "unprognostic (9.85e-11)" "unprognostic (9.21e-2)" "unprognostic (1.95e-1)" "unprognostic (8.12e-3)" "unprognostic (9.07e-2)" 0.9 0.6 4.2 0.3 6.6 0.1 1.0 5.4 6.5 0.8 2.5 0.5 0.4 0.4 1.0 0.2 0.5 0.6 1.6 4.6 3.9 0.8 0.2 1.4 0.8 4.8 4.1 1.2 0.6 0.1 0.8 0.6 5.3 0.9 0.3 1.2 0.8 0.3 1.8 1.5 0.5 0.1 3.4 17.4 0.5 3.2 4.2 0.1 0.8 0.7 0.4 0.4 0.5 4.0 0.3 2.9 2.6 0.9 4.7 3.2 0.3 1.1 4.1 2.4 2.2 0.1 2.0 0.0 0.6 1.2 1.2 0.1 0.6 0.4 1.0 0.8 0.8 2.1 0.5 0.7 0.5 1.0 4.7 3.8 1.0 1.5 0.2 4.5 1.0 0.9 0.5 1.3 1.6 1.7 0.0 0.2 1.5 0.2 0.2 0.0 0.5 0.7 0.4 0.5 1.6 0.9 2.4 0.1 1.2 0.6 1.1 0.2 0.8 6.4 0.9 1.1 0.4 2.4 0.5 1.3 4.5 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.2 6.6 5.4 6.5 4.6 3.9 4.8 4.1 5.3 3.4 4.2 4.0 0.6 3.2 2.8 4.2 0.4 0.6 0.2 0.1 1.2 3.4 1.8 1.3 1.5 1.5 0.2 0.0 0.0 0.3 0.1 0.5 0.0 0.3 1.8 0.2 0.8 0.8 1.2 0.0 11.1 0.2 0.1 0.7 0.0 0.9 0.0 0.9 1.4 0.0 0.1 16.8 12.2 0.3 0.0 0.0 0.4 0.7 0.3 0.5 0.0 1.9 0.6 0.3 0.0 7.1 2.6 0.5 0.1 2.2 0.0 0.5 0.2 0.0 0.7 0.9 0.0 0.6 1.4 17.2 4.6 0.3 0.9 0.0 0.3 6.8 0.3 0.2 SLCO1A2 "OATP, OATP-A, OATP1A2, SLC21A3" ENSG00000084453 "Solute carrier organic anion transporter family member 1A2" P46721 12 21264600-21419594 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 82.0;choroid plexus: 28.6" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 487.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 16.7;RPMI-8226: 12.0;SuSa: 16.1;U-266/70: 23.1;U-266/84: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071152 Supported "Plasma membrane" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA071152: AB_2686350" "unprognostic (5.43e-3)" "unprognostic (2.33e-1)" "unprognostic (1.28e-1)" "unprognostic (8.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.36e-2)" "unprognostic (7.63e-2)" "unprognostic (1.53e-1)" "unprognostic (3.82e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (8.82e-2)" "unprognostic (1.66e-4)" "unprognostic (2.52e-2)" "unprognostic (3.20e-1)" "unprognostic (1.24e-1)" 0.0 0.1 48.9 0.1 65.9 0.1 4.0 43.5 80.2 0.0 28.6 0.1 0.0 0.1 0.2 0.1 0.3 0.2 0.9 41.3 46.4 1.2 11.5 2.8 0.7 54.0 51.9 0.2 2.4 0.2 0.4 1.2 52.6 0.7 0.0 0.6 15.8 0.0 0.4 0.5 0.1 0.0 45.2 0.5 0.3 1.9 48.3 0.6 0.2 0.0 0.4 0.2 0.0 82.0 2.1 0.6 0.8 0.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 3.8 1.4 0.1 2.1 0.2 0.0 0.3 0.3 0.2 0.5 0.7 0.9 0.0 0.5 1.5 0.0 0.4 0.3 0.0 1.7 0.2 0.2 1.5 0.1 0.4 4.0 1.2 0.0 2.6 0.4 0.1 16.7 2.0 0.2 0.2 0.2 12.0 0.0 2.2 1.9 2.9 0.0 0.2 0.2 16.1 3.2 0.9 0.0 0.1 1.7 0.8 0.4 23.1 9.8 0.2 0.1 0.3 0.0 0.2 0.1 0.1 0.4 0.1 0.6 0.4 0.6 0.4 0.0 0.2 0.6 0.4 1.3 0.3 0.0 0.2 0.5 0.1 48.9 65.9 43.5 80.2 41.3 46.4 54.0 51.9 52.6 45.2 48.3 82.0 0.0 35.3 3.1 5.9 0.0 0.0 0.0 0.0 0.0 0.2 3.5 2.8 0.5 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.8 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 102.1 0.0 0.1 0.0 2.5 487.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 204.5;Hofbauer cells: 122.2;Kupffer cells: 155.8;Macrophages: 92.4;Microglial cells: 232.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 90.3;GAMG: 21.2;Hep G2: 20.4;HMC-1: 25.8;OE19: 111.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA020659: AB_1857219" "unprognostic (8.25e-2)" "unprognostic (5.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.57e-1)" "unprognostic (3.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-3)" "unprognostic (1.99e-1)" "unprognostic (2.09e-1)" "unprognostic (9.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.57e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" 39.9 31.5 40.1 34.0 35.9 2.9 12.1 34.0 37.4 18.1 21.3 30.9 42.1 9.5 3.6 19.7 13.2 28.4 15.6 31.9 47.2 21.0 229.6 60.7 60.1 75.7 53.4 9.4 22.1 7.9 5.1 43.9 63.0 6.1 23.6 1.5 8.4 9.6 5.6 4.3 51.3 26.3 49.7 46.4 15.0 6.0 80.4 16.7 10.1 8.0 28.5 26.3 6.2 55.1 0.0 0.7 2.8 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 90.3 0.0 0.1 0.1 0.0 21.2 0.2 0.0 0.0 0.0 1.1 0.0 15.0 1.0 20.4 0.0 1.1 25.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.3 8.7 0.0 0.1 0.0 0.1 0.1 111.1 0.0 0.0 2.4 9.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.3 0.0 1.5 1.8 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.1 35.9 34.0 37.4 31.9 47.2 75.7 53.4 63.0 49.7 80.4 55.1 4.7 0.0 8.9 1.3 0.7 1.9 0.0 0.0 1.8 3.4 0.9 1.4 2.8 11.5 1.8 0.0 0.0 0.9 0.1 14.7 1.9 0.0 2.8 0.0 0.1 28.8 0.0 2.7 0.5 0.2 2.3 3.6 0.5 0.0 22.9 6.1 3.6 204.5 122.2 0.0 0.5 6.6 0.0 155.8 8.9 1.7 10.8 92.4 0.0 232.3 2.0 0.2 0.0 1.5 0.6 0.1 14.6 10.5 1.4 0.0 46.7 8.2 0.7 0.7 0.0 3.0 1.1 0.4 0.2 4.5 0.4 2.5 0.7 0.4 13.3 0.1 SLIT1 "MEGF4, SLIL1, Slit-1, SLIT3" ENSG00000187122 "Slit guidance ligand 1" O75093 10 96998038-97185959 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 32.5;pituitary gland: 13.5" "Group enriched" "Detected in some" 6 "Early spermatids: 27.0;Excitatory neurons: 96.2;Inhibitory neurons: 34.6;Late spermatids: 25.5;Oligodendrocyte precursor cells: 25.1" "Group enriched" "Detected in many" 4 "glioma: 9.2;thyroid cancer: 10.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "JURKAT: 23.2;MOLT-4: 81.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006879 Approved "Plasma membrane" "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA006879: AB_1078197" "unprognostic (2.72e-1)" "unprognostic (2.25e-2)" "unprognostic (5.67e-3)" "unprognostic (1.43e-5)" "unprognostic (8.40e-2)" "unprognostic (2.60e-3)" "unprognostic (4.57e-2)" "unprognostic (1.81e-2)" "unprognostic (3.53e-1)" "unprognostic (6.06e-2)" "unprognostic (2.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.08e-5)" "unprognostic (1.66e-1)" "unprognostic (2.18e-1)" "unprognostic (1.21e-1)" "unprognostic (4.39e-3)" 0.4 0.1 28.6 0.2 32.5 0.2 0.1 0.0 29.8 0.1 0.0 0.5 0.1 0.1 0.0 0.0 0.2 0.0 0.1 28.7 5.2 0.1 0.1 0.2 0.1 0.0 2.1 0.1 0.6 0.1 13.5 0.0 0.0 0.3 0.1 0.8 0.1 0.0 0.1 0.0 0.2 0.1 1.6 0.3 0.3 1.8 14.1 2.4 2.5 0.0 0.1 0.1 0.1 7.4 0.0 0.1 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.1 0.3 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 23.2 0.0 0.6 0.0 0.2 81.0 0.3 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 4.9 2.1 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.1 1.7 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 28.6 32.5 0.0 29.8 28.7 5.2 0.0 2.1 0.0 1.6 14.1 7.4 0.2 0.0 0.0 6.5 0.5 0.0 0.1 0.0 0.0 3.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 27.0 0.5 0.1 0.1 1.8 0.0 96.2 0.0 0.0 0.2 0.0 1.1 0.0 0.2 0.0 0.0 0.5 0.0 34.6 0.0 0.0 0.3 0.0 25.5 0.0 0.3 0.0 2.8 0.2 0.1 0.0 25.1 3.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.5 0.2 0.0 0.1 0.2 3.4 2.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 256.7;Inhibitory neurons: 544.9;Oligodendrocytes: 157.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.0;BJ hTERT+: 200.8;BJ hTERT+ SV40 Large T+: 97.8;fHDF/TERT166: 117.8;HBF TERT88: 112.0;HEK 293: 88.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" 8.0 24.9 3.2 3.3 6.4 0.0 9.4 0.0 14.0 24.0 11.7 11.5 2.4 16.4 9.9 5.8 13.1 9.4 7.8 6.6 20.5 12.3 2.0 34.9 1.8 7.9 3.1 4.3 2.8 1.5 8.8 25.2 4.5 12.6 5.4 13.2 6.1 15.7 2.9 3.8 4.8 24.9 0.4 14.2 9.0 1.3 17.6 2.4 9.2 5.1 1.2 13.1 13.9 2.4 0.1 0.0 54.6 0.0 37.8 34.8 1.7 98.0 200.8 97.8 36.9 0.4 0.1 0.0 3.4 117.8 0.2 1.2 15.7 7.9 112.0 0.2 88.3 0.0 0.4 0.0 7.2 0.9 0.0 8.5 0.0 63.6 18.6 2.1 35.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 1.7 0.0 6.3 61.2 0.5 0.0 1.0 0.1 3.5 0.8 0.0 0.2 0.4 1.9 0.2 0.2 2.0 34.9 5.0 35.0 54.2 0.0 0.1 0.0 0.9 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 6.4 0.0 14.0 6.6 20.5 7.9 3.1 4.5 0.4 17.6 2.4 1.6 0.0 9.0 10.1 0.0 8.0 2.0 0.1 0.6 47.6 1.0 0.6 5.2 1.5 1.3 0.0 0.0 1.1 0.0 0.6 1.9 1.7 0.6 6.4 1.9 2.0 1.2 0.0 256.7 0.5 1.2 58.8 0.0 7.1 2.5 1.3 4.2 0.2 1.9 0.0 544.9 0.0 0.0 1.0 9.7 1.7 26.4 0.7 8.8 31.9 0.0 1.3 0.0 43.7 157.9 0.2 0.0 26.7 0.1 3.7 0.0 11.5 7.4 2.1 6.6 3.2 6.4 0.2 1.7 1.2 6.7 2.1 1.1 20.3 0.1 1.9 SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.3;Fibroblasts: 112.7;Sertoli cells: 85.5;Smooth muscle cells: 99.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 310.3;fHDF/TERT166: 116.0;RT4: 101.1;SH-SY5Y: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" 61.9 20.7 10.0 11.9 10.6 0.1 32.7 11.9 7.5 36.4 0.3 20.0 5.4 23.9 8.8 21.4 22.2 43.5 39.7 12.3 4.3 16.7 1.5 38.1 6.2 12.9 0.7 17.0 7.8 44.9 4.4 21.7 11.6 10.3 9.7 3.1 16.8 15.4 4.4 25.8 10.4 27.1 0.3 14.3 10.1 2.7 6.9 20.0 23.3 6.5 4.2 55.5 24.3 2.2 0.0 11.0 0.1 0.0 310.3 5.7 0.0 18.1 3.1 4.0 8.4 0.1 0.0 0.0 4.2 116.0 13.1 0.0 2.9 1.2 0.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 4.2 0.5 3.9 44.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 101.1 1.1 73.3 0.0 0.0 0.0 12.5 0.0 0.0 0.0 3.0 1.9 25.5 0.1 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 10.0 10.6 11.9 7.5 12.3 4.3 12.9 0.7 11.6 0.3 6.9 2.2 11.7 0.0 2.3 4.2 0.5 26.6 1.8 5.5 3.4 8.6 1.1 3.8 25.9 0.0 0.4 0.0 0.0 2.3 0.5 0.0 0.0 0.2 11.9 1.3 35.7 5.4 0.0 0.0 202.3 0.0 0.5 112.7 4.6 3.6 1.3 0.5 1.8 0.0 1.2 0.0 20.2 0.0 0.0 0.0 32.5 8.2 0.9 1.1 35.6 14.0 0.0 13.7 0.0 8.0 2.9 0.0 0.0 0.4 0.8 1.1 0.1 1.9 0.2 0.9 85.5 1.8 99.3 1.2 2.2 1.1 17.6 1.1 1.8 0.3 0.0 0.8 SLITRK3 KIAA0848 ENSG00000121871 "SLIT and NTRK like family member 3" O94933 3 165186720-165197109 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.0;fallopian tube: 9.6;liver: 7.9" "Group enriched" "Detected in some" 6 "Bipolar cells: 8.4;Excitatory neurons: 11.0;Inhibitory neurons: 15.9;Oligodendrocyte precursor cells: 21.1" "Cancer enriched" "Detected in single" 22 "glioma: 7.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.6;HAP1: 2.2;SCLC-21H: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017636, HPA048042" Enhanced Approved Mitochondria No NA 2600000 "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA017636: AB_1857232, HPA048042: AB_2732542" "unprognostic (8.91e-2)" "unprognostic (1.44e-1)" "unprognostic (4.08e-2)" "unprognostic (1.96e-1)" "unprognostic (5.16e-2)" "unprognostic (1.76e-1)" "unprognostic (9.59e-2)" "unprognostic (2.95e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-1)" "unprognostic (6.74e-3)" "unprognostic (5.03e-1)" "unprognostic (2.38e-1)" "unprognostic (8.03e-4)" 0.1 0.1 3.4 1.0 3.1 0.0 0.1 4.1 8.4 5.4 0.0 2.6 0.4 7.3 0.9 4.4 9.6 0.2 0.4 9.0 2.8 0.1 7.9 0.3 0.0 0.2 0.1 0.9 0.0 0.0 0.1 0.0 0.5 1.7 1.6 3.1 0.2 5.4 0.3 0.0 1.1 3.7 0.9 0.0 0.4 0.4 0.7 0.0 0.1 0.0 0.0 0.5 0.9 1.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.1 4.1 8.4 9.0 2.8 0.2 0.1 0.5 0.9 0.7 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 2.2 0.0 0.0 15.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 21.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLPI "ALK1, ALP, BLPI, HUSI, HUSI-I, WAP4, WFDC4" ENSG00000124107 "Secretory leukocyte peptidase inhibitor" P03973 20 45252239-45254564 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 27919.2;salivary gland: 14140.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 4134.5;Basal respiratory cells: 18759.4;Club cells: 20435.8;Respiratory ciliated cells: 8096.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 79 "neutrophil: 321.8" "Lineage enriched" "Detected in many" 79 "granulocytes: 321.8" "Cell line enhanced" "Detected in many" "EFO-21: 1719.5;hTCEpi: 2037.1;OE19: 767.9;SiHa: 622.1;THP-1: 531.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002303, HPA027774" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 26400000 9600000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "CAB002303: AB_564008, HPA027774: AB_10602405" "unprognostic (2.31e-2)" "unprognostic (3.07e-1)" "unprognostic (3.10e-2)" "unprognostic (2.06e-1)" "unprognostic (1.63e-1)" "unprognostic (3.16e-2)" "unprognostic (9.98e-2)" "unprognostic (2.90e-1)" "unprognostic (3.23e-1)" "unprognostic (1.83e-3)" "unprognostic (4.01e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (6.91e-5)" "unprognostic (1.53e-1)" "unprognostic (2.15e-1)" "unprognostic (8.81e-2)" "unprognostic (8.31e-2)" 259.4 13.8 4.1 70.8 4.3 353.5 306.7 5.0 22.5 27919.2 28.9 97.8 4.5 107.1 16.5 1372.7 714.2 294.7 68.4 4.5 4.8 382.6 268.0 1181.7 2.0 5.6 5.5 11.5 36.1 5.5 470.2 8.3 5.5 112.6 106.7 0.6 14140.1 2946.3 599.9 272.4 19.9 14.0 4.8 22.5 154.7 28.1 10.4 47.7 30.4 51.5 215.8 226.6 685.3 4.8 4.9 19.4 0.0 0.3 0.2 0.0 1.1 0.1 0.0 0.1 0.0 1.5 318.7 0.9 1719.5 0.2 23.9 132.8 0.0 64.1 0.0 8.6 0.3 0.3 227.1 0.2 326.4 0.5 1.0 8.8 2037.1 0.1 134.0 0.0 0.2 0.0 0.2 0.3 0.0 0.4 0.4 24.4 0.4 767.9 120.1 0.6 0.7 0.1 355.5 14.6 0.3 0.0 622.1 131.4 1.8 0.4 2.8 531.8 0.3 0.4 8.5 1.2 1.1 1.2 9.7 6.1 0.0 33.0 0.5 3.6 0.9 0.4 0.1 3.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 321.8 0.0 4.0 0.0 0.0 7.9 4.1 4.3 5.0 22.5 4.5 4.8 5.6 5.5 5.5 4.8 10.4 4.8 6.3 1807.7 4134.5 0.3 5.4 100.7 1330.7 18759.4 2.2 0.0 594.2 607.6 3.9 1609.9 20435.8 3428.2 0.0 2.3 10.1 225.8 0.0 407.5 381.6 632.0 170.7 43.3 200.2 18.7 0.0 258.9 1.2 326.0 193.7 1398.8 77.0 0.0 15.7 508.5 6.8 0.0 0.0 74.7 2616.3 8.5 73.3 69.8 25.4 27.1 39.2 0.0 5.3 0.0 0.0 1.0 0.1 901.6 370.3 0.0 1.3 1289.4 2.7 3.4 8096.4 0.0 0.0 8.6 971.2 1.8 1.8 347.3 138.9 2.1 29.5 0.0 224.5 3338.5 SLTM "FLJ13213, Met" ENSG00000137776 "SAFB like transcription modulator" Q9NWH9 15 58879050-58933679 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040256, HPA040381" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA040256: AB_10674990, HPA040381: AB_2676953" "unprognostic (2.36e-1)" "unprognostic (6.56e-2)" "unprognostic (2.23e-1)" "unprognostic (1.81e-1)" "unprognostic (2.52e-3)" "unprognostic (9.65e-2)" "unprognostic (1.00e-1)" "unprognostic (2.48e-1)" "unprognostic (2.82e-3)" "unprognostic (3.44e-1)" "unprognostic (2.09e-1)" "unprognostic (6.10e-3)" "unprognostic (8.03e-2)" "unprognostic (7.09e-2)" "unprognostic (3.69e-1)" "unprognostic (5.71e-2)" "unprognostic (3.24e-3)" 31.2 21.5 27.3 31.5 30.6 57.7 29.5 35.6 34.6 29.9 26.3 30.0 30.0 27.6 20.8 38.5 27.8 23.8 28.4 25.6 28.6 33.6 34.9 28.2 42.7 28.3 29.1 29.6 24.9 36.1 28.4 21.0 28.6 29.2 32.1 44.9 30.6 24.2 46.1 35.1 33.4 25.8 27.5 38.1 38.9 27.8 28.7 57.3 34.1 43.6 44.1 33.8 31.3 31.3 77.8 84.1 72.0 36.6 48.1 36.2 60.6 55.1 64.3 49.9 48.2 58.4 45.7 144.6 50.5 50.8 54.4 67.9 72.3 62.9 68.7 93.7 46.4 105.4 91.8 44.7 42.0 83.8 78.1 34.1 61.0 52.8 44.1 30.4 46.9 66.0 95.5 81.7 58.2 56.1 84.1 64.6 80.9 46.3 40.5 63.6 65.4 70.1 60.2 99.8 58.9 50.8 57.0 55.1 57.8 79.3 44.0 90.1 48.6 60.2 88.5 66.3 74.6 57.3 123.1 105.5 47.6 101.7 61.5 67.9 30.3 44.4 45.2 29.5 46.1 53.5 36.0 39.3 31.2 47.3 39.2 35.6 42.8 47.0 37.7 53.6 36.5 22.7 27.3 30.6 35.6 34.6 25.6 28.6 28.3 29.1 28.6 27.5 28.7 31.3 92.5 153.8 161.2 61.4 125.8 96.9 100.2 85.6 107.0 116.3 77.3 66.0 107.8 64.3 122.8 106.7 98.0 73.5 155.9 88.4 78.2 98.4 100.8 110.5 99.0 94.7 73.4 115.7 67.7 115.7 160.1 94.3 99.4 119.1 118.9 75.3 63.9 104.1 63.9 119.5 67.3 94.4 59.0 88.6 73.0 120.8 86.3 108.8 78.2 72.1 121.0 84.9 126.7 74.4 141.8 131.1 76.5 88.4 140.0 92.4 57.4 90.6 103.9 145.3 72.3 106.6 95.6 215.1 85.2 100.0 104.6 112.5 134.9 78.0 94.0 125.6 SLURP1 "ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM" ENSG00000126233 "Secreted LY6/PLAUR domain containing 1" P55000 8 142740949-142742406 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Cytokine "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 1039.2;skin 1: 858.5" "Group enriched" "Detected in some" 16 "Squamous epithelial cells: 20.8;Suprabasal keratinocytes: 65.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 66.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.3;MCF7: 1.5;RT4: 1.1;T-47d: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050967 Approved "Secreted in other tissues" NA NA 7700000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA050967: AB_2681293" "unprognostic (1.22e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.42e-2)" "unprognostic (1.84e-1)" "unprognostic (7.32e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-4)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (1.43e-1)" 0.9 0.6 0.1 0.0 0.0 0.0 11.3 0.7 0.5 105.0 0.0 0.3 0.0 0.2 0.0 1039.2 0.2 0.2 0.4 0.1 0.0 0.2 0.5 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 70.1 0.0 1.4 858.5 0.3 0.0 0.0 0.2 0.8 0.3 0.1 0.9 0.2 0.0 17.4 0.3 206.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.6 0.0 0.0 1.8 1.5 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 20.8 65.8 0.0 0.0 0.0 0.0 0.8 SLURP2 ENSG00000283992 "Secreted LY6/PLAUR domain containing 2" P0DP57 8 142764338-142769828 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 870.8;skin 1: 334.1;vagina: 219.7" "Cell type enhanced" "Detected in single" "Pancreatic endocrine cells: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HaCaT: 28.5" "Secreted in other tissues" NA NA 3100000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" 1.1 0.1 0.4 0.0 0.7 0.0 2.0 2.9 2.4 187.1 0.0 19.4 0.3 5.0 0.2 870.8 4.0 0.2 1.2 1.0 0.1 0.2 0.3 0.5 0.0 1.8 0.2 1.0 0.4 0.0 0.2 0.1 1.7 6.5 0.2 0.3 75.2 2.1 0.4 334.1 2.8 0.8 0.2 0.3 5.8 0.3 0.4 1.2 0.6 0.0 22.9 9.9 219.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.1 6.2 0.0 0.0 28.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 2.9 2.4 1.0 0.1 1.8 0.2 1.7 0.2 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMARCA2 "BAF190, BRM, hBRM, hSNF2a, SNF2, SNF2L2, SNF2LA, Sth1p, SWI2" ENSG00000080503 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2" P51531 9 1980290-2193624 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase" "Disease variant, Hypotrichosis, Mental retardation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 246.5;Inhibitory neurons: 263.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "HDLM-2: 1486.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029981, CAB037276" Enhanced Approved "Nucleoplasm,Vesicles,Intermediate filaments" NA NA 19000 "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB037276: AB_477083, HPA029981: AB_10602406" "unprognostic (5.34e-2)" "unprognostic (1.99e-2)" "unprognostic (6.27e-2)" "unprognostic (6.53e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (4.91e-2)" "unprognostic (2.80e-2)" "unprognostic (2.62e-1)" "unprognostic (3.97e-1)" "unprognostic (3.60e-3)" "unprognostic (9.64e-2)" "prognostic favorable (1.26e-6)" "unprognostic (3.09e-1)" "unprognostic (2.81e-1)" "unprognostic (8.32e-3)" "unprognostic (8.50e-2)" 51.9 55.9 68.9 36.1 73.9 95.7 62.0 87.4 81.7 42.1 40.2 31.0 20.2 53.2 57.3 41.7 57.4 46.0 43.8 60.3 53.7 45.9 58.3 40.3 50.9 43.2 54.4 166.0 36.8 170.3 32.7 48.2 50.6 42.5 31.7 63.6 50.7 53.2 97.7 48.2 27.7 44.2 40.3 52.3 32.0 56.3 55.7 42.2 55.7 60.1 47.8 31.8 28.8 52.9 45.7 32.9 23.7 33.8 47.2 56.6 71.7 59.4 44.6 24.9 19.5 0.5 17.7 76.2 22.0 50.7 13.5 18.8 12.9 46.5 17.6 1486.7 20.2 208.3 88.2 16.2 18.7 88.3 118.1 37.6 17.5 24.9 46.4 44.9 40.3 35.4 7.3 255.1 43.0 19.1 22.2 72.3 23.4 26.4 12.6 97.6 30.5 69.4 57.6 40.9 15.3 14.0 36.2 8.3 14.9 34.1 16.3 55.8 49.1 40.6 19.8 25.8 27.3 22.9 31.8 33.6 43.5 32.5 11.4 26.1 5.2 15.8 10.8 7.2 10.4 12.3 10.5 11.2 6.4 9.4 13.1 10.3 14.6 9.9 10.3 12.5 12.6 5.0 68.9 73.9 87.4 81.7 60.3 53.7 43.2 54.4 50.6 40.3 55.7 52.9 83.9 73.7 70.6 246.5 57.2 58.6 18.3 55.0 82.6 57.6 103.7 74.3 95.2 31.5 54.1 106.7 37.5 99.3 102.8 32.0 31.3 30.6 38.0 44.1 61.6 69.0 37.2 41.2 216.2 22.4 24.5 65.7 19.4 45.2 48.0 27.9 36.8 62.0 31.5 35.3 263.2 31.2 48.8 54.9 34.7 22.6 76.7 57.5 49.8 142.4 45.2 53.4 43.3 120.6 100.8 18.7 15.1 86.9 71.4 13.9 26.9 18.5 88.3 37.4 13.1 58.7 40.3 42.9 14.6 66.2 52.7 88.7 74.8 56.1 28.2 12.7 SMARCD1 "BAF60A, CRACD1, Rsc6p" ENSG00000066117 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1" Q96GM5 12 50085200-50100707 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Chromatin regulator" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004101 Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Vesicles "HPA004101: AB_1080026" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-2)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "prognostic unfavorable (2.53e-8)" "unprognostic (3.62e-2)" "unprognostic (1.44e-1)" "unprognostic (4.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.10e-2)" "unprognostic (1.20e-3)" "unprognostic (2.18e-1)" "unprognostic (3.45e-1)" "unprognostic (1.38e-1)" "unprognostic (5.04e-2)" 25.8 28.1 25.2 23.2 27.6 44.0 24.9 24.4 27.0 23.5 20.8 22.0 23.2 27.9 27.1 27.5 23.8 17.9 18.3 26.3 23.8 25.3 19.0 23.9 35.0 25.7 25.7 26.4 22.5 47.3 19.7 28.9 25.3 23.2 27.2 25.1 24.3 21.8 16.9 24.3 27.8 28.8 24.8 31.3 20.5 23.8 25.8 57.2 26.8 16.1 47.6 23.5 21.7 27.6 28.4 47.6 134.8 75.8 41.1 38.9 68.1 35.1 62.0 100.3 58.2 130.0 42.1 109.4 51.0 67.2 44.4 35.4 112.9 91.5 87.3 84.4 87.0 107.2 49.4 75.8 49.3 95.0 41.1 40.2 60.2 59.8 107.4 66.1 119.5 114.0 93.1 64.8 50.6 67.7 137.6 54.0 166.0 43.2 76.6 165.5 34.9 96.0 57.3 66.1 71.4 121.3 73.1 35.2 139.3 100.4 79.4 78.7 70.4 50.1 56.0 31.7 69.9 91.6 88.2 95.4 40.6 37.7 56.9 3.4 1.2 2.2 2.9 1.2 2.9 3.6 1.6 2.0 1.8 2.7 1.0 3.3 0.5 1.7 1.9 3.5 2.7 1.2 25.2 27.6 24.4 27.0 26.3 23.8 25.7 25.7 25.3 24.8 25.8 27.6 29.7 0.0 9.6 11.1 42.9 16.6 22.3 17.7 42.7 33.7 33.2 30.2 6.5 15.7 20.5 27.6 20.9 21.1 39.6 21.6 52.8 32.8 4.3 20.0 36.9 30.1 31.1 25.7 9.3 29.0 19.4 17.8 14.8 30.5 16.5 40.0 17.5 15.1 17.3 26.9 10.5 18.2 10.2 14.4 13.1 9.1 16.4 16.8 17.8 7.5 27.1 26.5 29.9 11.1 17.1 36.8 14.8 16.1 28.9 28.8 19.5 47.9 9.4 28.8 32.9 31.6 28.2 28.4 36.5 31.3 19.6 11.1 30.0 26.8 19.1 15.9 SMARCD2 "BAF60B, CRACD2, PRO2451, Rsc6p" ENSG00000108604 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2" Q92925 17 63832081-63843065 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 101.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059934, HPA061348" Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA059934: AB_2684170, HPA061348: AB_2684486" "unprognostic (1.70e-1)" "unprognostic (2.17e-2)" "unprognostic (8.04e-2)" "unprognostic (3.84e-2)" "unprognostic (1.59e-1)" "unprognostic (2.00e-2)" "unprognostic (7.84e-2)" "unprognostic (4.79e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (4.75e-1)" "unprognostic (1.26e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (1.81e-2)" "unprognostic (1.26e-1)" "unprognostic (1.79e-3)" "unprognostic (6.80e-2)" 53.8 55.2 23.3 44.6 28.1 71.6 65.9 35.5 28.5 48.0 29.1 49.9 51.1 37.4 58.5 71.3 52.9 33.1 31.2 22.9 23.2 26.4 54.9 46.7 66.0 27.7 26.7 38.3 89.5 42.8 36.7 47.8 27.0 52.7 46.6 17.6 78.0 49.0 25.3 97.0 49.8 32.4 25.5 60.6 68.2 42.7 25.6 70.2 33.8 34.2 70.1 52.3 55.9 31.7 142.9 87.9 21.3 93.0 133.6 196.1 139.7 52.5 64.1 97.5 61.7 101.7 76.8 163.0 32.5 79.0 43.9 99.4 65.7 99.1 57.3 61.1 169.5 109.3 40.3 141.7 102.3 159.5 128.9 154.3 122.0 55.3 42.1 56.4 78.3 110.8 89.5 101.7 57.2 279.1 203.8 132.3 51.3 202.0 96.9 195.0 77.8 185.0 66.9 96.0 80.2 145.9 79.2 228.4 97.1 69.3 212.2 121.7 58.4 67.7 52.5 61.4 90.7 119.8 113.2 113.5 54.1 129.6 50.4 4.2 9.1 8.8 9.4 8.4 5.6 7.2 9.9 9.8 12.1 9.5 6.3 8.5 10.8 8.0 10.0 10.1 11.5 6.0 23.3 28.1 35.5 28.5 22.9 23.2 27.7 26.7 27.0 25.5 25.6 31.7 14.8 28.9 42.4 19.9 18.2 22.9 23.6 14.3 26.2 9.7 47.1 41.0 5.9 30.0 25.2 16.5 6.2 54.9 21.1 36.0 3.9 16.9 1.0 17.6 25.3 17.4 33.0 12.6 7.2 19.6 38.2 25.8 18.8 20.7 14.0 88.1 25.7 83.3 22.0 11.8 5.8 42.0 12.2 36.9 19.6 5.4 49.4 23.1 14.2 8.4 31.9 16.9 15.5 6.6 10.7 21.0 26.2 30.9 12.6 19.0 30.0 11.6 23.8 12.4 32.9 21.9 14.6 12.3 22.4 29.7 31.1 52.9 16.7 101.7 40.8 24.1 SMG6 "C17orf31, EST1A, KIAA0732, SMG-6" ENSG00000070366 "SMG6 nonsense mediated mRNA decay factor" Q86US8 17 2059839-2303785 "Plasma proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042932 Approved Supported Nucleoli,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoli Cytosol "HPA042932: AB_10964261" "unprognostic (5.22e-2)" "unprognostic (1.20e-1)" "unprognostic (5.30e-1)" "unprognostic (4.41e-2)" "unprognostic (1.33e-1)" "unprognostic (9.33e-3)" "unprognostic (1.62e-1)" "unprognostic (2.08e-1)" "unprognostic (4.75e-2)" "unprognostic (7.63e-2)" "unprognostic (4.78e-2)" "unprognostic (1.31e-1)" "prognostic favorable (1.30e-6)" "unprognostic (1.90e-2)" "unprognostic (2.67e-1)" "unprognostic (2.61e-1)" "unprognostic (3.08e-2)" 12.2 13.0 15.5 12.3 14.6 13.6 10.5 17.6 15.0 16.4 13.2 11.4 9.3 26.6 11.1 16.4 21.7 17.2 14.0 13.8 17.8 12.3 7.4 11.9 12.3 19.9 17.3 37.5 7.4 14.4 13.3 10.5 14.3 13.9 9.4 19.2 10.4 12.8 12.9 16.0 10.9 18.9 12.5 9.8 9.6 19.5 16.0 23.1 11.7 9.1 10.9 13.1 12.0 14.8 14.9 22.5 31.7 20.6 33.6 27.0 16.3 23.6 25.9 26.3 22.2 27.6 7.3 15.7 8.3 34.8 12.0 21.3 23.5 20.1 27.4 15.7 14.7 15.3 11.8 13.5 19.2 8.2 10.5 38.5 14.5 21.2 18.6 42.6 24.3 15.3 12.8 18.5 19.9 11.7 20.8 6.6 10.2 8.9 11.7 21.4 20.2 6.2 15.2 13.5 5.3 16.1 24.6 7.1 10.2 22.2 11.1 6.0 32.2 24.0 13.1 25.6 25.1 16.0 10.5 7.2 19.1 9.1 14.0 3.0 0.7 0.8 1.3 0.3 1.3 0.5 1.1 1.3 0.4 0.7 1.5 1.1 0.5 2.0 1.6 1.3 0.6 0.6 15.5 14.6 17.6 15.0 13.8 17.8 19.9 17.3 14.3 12.5 16.0 14.8 17.2 22.4 18.4 41.4 13.2 7.9 13.8 13.1 10.2 35.6 13.8 14.5 8.0 7.2 11.8 14.7 75.0 16.5 17.7 17.9 5.9 13.8 22.5 19.4 37.1 20.3 4.2 12.8 57.1 12.4 10.7 21.0 18.3 21.3 10.8 20.3 17.9 9.1 10.3 47.1 61.7 14.4 16.2 8.7 6.8 36.9 16.8 10.6 8.8 81.5 15.9 24.8 21.6 44.7 64.3 17.2 15.2 19.9 14.6 14.7 10.1 7.6 17.9 50.5 26.3 27.1 20.4 63.7 59.0 15.1 8.7 17.4 24.9 22.4 13.5 14.2 SMIM10L1 ENSG00000256537 "Small integral membrane protein 10 like 1" P0DMW3 12 11171194-11176016 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" "unprognostic (2.27e-1)" "unprognostic (5.11e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-2)" "unprognostic (3.49e-2)" "unprognostic (1.36e-1)" "unprognostic (2.97e-3)" "unprognostic (3.14e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.71e-4)" "unprognostic (2.80e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (3.56e-4)" "unprognostic (8.37e-2)" "unprognostic (1.38e-1)" "unprognostic (1.45e-1)" "prognostic favorable (9.70e-4)" 5.9 16.1 12.0 4.8 12.1 5.8 4.9 11.3 15.5 4.4 11.8 9.8 5.2 6.7 7.9 4.2 4.6 3.5 14.4 12.4 12.5 7.5 10.6 4.7 4.7 12.3 12.5 3.8 4.8 5.6 8.8 4.8 12.3 6.6 4.5 7.3 11.5 6.2 21.7 2.7 5.9 5.5 13.0 6.1 6.4 3.2 12.4 6.2 6.0 10.2 4.0 6.9 3.9 12.6 10.5 6.3 16.6 7.3 13.2 9.6 14.5 15.4 9.2 9.9 7.7 13.3 9.2 8.7 6.7 8.7 12.6 6.8 9.9 7.7 12.6 30.3 11.7 15.9 9.2 12.9 9.1 22.4 5.1 8.5 6.7 10.1 10.1 11.8 8.1 14.5 11.6 7.7 11.4 10.1 15.7 18.6 26.9 5.7 8.1 13.0 19.8 9.3 12.5 11.9 8.8 9.7 12.5 7.6 23.0 27.0 4.1 15.1 9.9 17.7 25.1 7.7 15.5 6.6 14.5 21.3 12.9 13.0 16.3 22.1 9.7 11.4 8.9 8.3 9.6 6.1 9.3 9.4 7.9 7.4 10.3 8.5 1.2 12.8 7.9 9.6 10.4 9.0 12.0 12.1 11.3 15.5 12.4 12.5 12.3 12.5 12.3 13.0 12.4 12.6 33.8 16.0 27.4 0.0 25.6 0.0 15.3 0.0 23.3 26.7 33.6 38.2 88.4 35.8 18.0 7.3 25.0 56.7 47.3 9.3 52.8 48.7 5.2 33.1 26.0 36.1 12.2 40.0 0.0 50.7 23.9 28.0 17.3 21.0 16.4 24.9 29.3 34.9 43.8 26.9 0.0 18.5 0.0 25.8 0.0 9.9 26.4 26.8 0.0 0.0 38.5 29.5 56.7 0.0 0.0 52.7 13.3 32.4 41.8 23.4 38.0 68.1 16.8 34.4 32.9 22.9 33.6 11.5 22.0 19.8 0.0 17.9 30.7 46.8 17.3 11.1 SMIM11A "C21orf51, FAM165B, SMIM11" ENSG00000205670 "Small integral membrane protein 11A" P58511 21 34375480-34416961 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "Gastric mucus-secreting cells: 12.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA051321 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Focal adhesion sites" "HPA051321: AB_2681440" "unprognostic (2.62e-2)" "unprognostic (4.28e-2)" "unprognostic (1.27e-1)" "unprognostic (5.86e-3)" "unprognostic (1.90e-1)" "unprognostic (1.66e-1)" "unprognostic (3.04e-1)" "unprognostic (4.48e-2)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" "unprognostic (8.84e-2)" "unprognostic (4.83e-3)" 10.2 8.9 19.8 12.1 20.6 13.0 6.6 20.4 32.6 10.3 24.4 7.5 14.9 9.7 14.5 9.3 9.2 13.6 21.9 19.9 20.8 17.8 14.5 8.1 15.8 21.4 20.2 16.7 11.6 11.2 3.6 5.8 21.0 10.5 6.5 13.2 14.3 4.8 35.9 6.3 11.7 11.3 21.5 11.4 30.5 6.3 20.0 6.7 20.6 11.4 6.5 12.7 2.7 23.5 24.7 9.8 11.1 33.0 21.0 6.5 22.6 9.0 4.3 12.5 25.1 12.7 22.7 57.4 11.8 11.6 16.5 15.1 18.8 0.7 11.9 32.0 8.9 33.1 23.0 12.7 19.0 55.6 7.8 15.5 10.8 13.6 31.1 24.5 14.2 12.1 51.4 65.7 13.2 13.2 2.2 43.5 52.2 15.5 34.5 31.1 25.2 82.5 10.8 6.2 28.3 20.4 14.8 18.5 39.0 20.3 18.2 25.1 18.1 18.1 13.4 8.0 16.9 25.1 28.3 54.0 33.6 70.0 33.0 5.6 6.3 14.9 6.9 10.1 11.4 6.5 11.7 16.8 8.5 17.1 8.5 11.4 3.6 14.4 9.2 7.6 14.1 9.5 19.8 20.6 20.4 32.6 19.9 20.8 21.4 20.2 21.0 21.5 20.0 23.5 0.1 3.2 2.6 0.0 0.4 0.0 0.4 0.0 0.0 0.8 0.8 0.3 0.0 0.0 0.6 0.0 0.0 0.3 0.1 0.3 1.9 1.5 0.4 0.1 0.4 0.7 1.2 0.0 0.0 0.7 0.3 0.7 12.8 0.2 0.0 0.2 0.7 1.4 0.7 0.0 0.0 0.8 0.0 0.6 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.9 0.3 0.4 0.6 0.3 1.4 2.2 2.2 0.4 0.0 0.3 0.3 0.6 0.5 0.0 0.0 0.1 0.4 0.1 0.6 0.1 SMIM11B ENSG00000273590 "Small integral membrane protein 11B" Q8TCY0 21 7744962-7777853 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Alveolar cells type 2: 5.6;Club cells: 4.3;Distal tubular cells: 3.9;granulocytes: 5.1;Respiratory ciliated cells: 10.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA051321 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Focal adhesion sites" "HPA051321: AB_2681440" "unprognostic (1.99e-1)" "unprognostic (1.78e-1)" "unprognostic (1.35e-1)" 14.6 17.0 22.5 1.1 22.6 0.5 15.6 21.7 24.1 17.6 21.7 23.3 2.1 16.8 15.0 9.3 19.2 3.1 30.7 22.3 22.5 24.3 20.6 11.3 4.8 24.7 23.1 20.6 18.6 9.1 21.3 4.2 22.2 17.4 5.7 10.0 15.4 11.2 37.3 9.8 13.9 3.4 19.7 14.0 58.2 6.5 22.4 12.2 19.5 16.3 8.5 18.4 14.3 23.4 23.6 9.6 7.7 17.3 19.0 37.9 0.2 8.8 30.0 11.2 0.8 1.0 1.4 1.1 7.0 14.3 23.8 1.1 17.0 27.7 10.0 34.3 45.9 19.2 1.2 13.8 19.5 3.1 25.9 18.8 26.6 0.4 1.4 7.9 14.5 29.3 31.2 3.6 10.6 11.9 26.6 2.1 0.6 36.3 0.6 1.1 0.4 1.2 34.7 6.2 16.2 1.9 21.6 15.3 17.7 0.6 28.2 0.8 3.1 10.9 4.5 9.2 9.8 19.2 20.6 1.5 0.1 9.9 1.5 1.5 11.0 4.6 11.6 5.8 11.3 19.6 9.1 6.0 11.4 12.2 16.1 9.7 0.9 1.4 5.0 8.4 14.7 6.4 22.5 22.6 21.7 24.1 22.3 22.5 24.7 23.1 22.2 19.7 22.4 23.4 0.1 16.0 5.6 0.0 0.2 0.0 0.6 0.0 0.0 0.8 0.8 0.3 0.0 1.5 4.3 0.0 0.0 0.3 0.3 0.3 3.9 0.5 0.2 0.2 0.1 0.4 0.0 2.7 0.0 0.4 0.3 2.1 0.0 0.1 5.1 0.1 0.4 0.6 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.3 0.3 0.3 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.3 0.1 0.4 0.1 0.3 0.3 1.9 10.9 0.3 0.0 0.9 0.1 0.3 0.4 0.0 0.0 0.3 0.6 0.1 0.5 0.3 SMIM15 "C5orf43, DKFZP686E2158" ENSG00000188725 "Small integral membrane protein 15" Q7Z3B0 5 61157704-61162468 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (1.18e-1)" "unprognostic (2.56e-1)" "unprognostic (2.33e-2)" "unprognostic (3.82e-1)" "unprognostic (3.32e-2)" "unprognostic (6.03e-2)" "unprognostic (9.83e-3)" "unprognostic (4.43e-2)" "unprognostic (2.44e-2)" "unprognostic (4.09e-1)" "unprognostic (5.08e-2)" "unprognostic (1.72e-1)" "unprognostic (5.34e-3)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (1.89e-1)" "prognostic favorable (9.23e-4)" 19.0 23.6 13.5 24.6 14.7 22.5 29.1 14.4 17.2 26.9 12.0 49.1 42.6 22.3 23.4 32.5 30.9 25.1 15.8 12.8 15.2 31.8 43.3 24.3 26.8 14.1 13.7 33.1 27.5 36.4 16.1 30.3 14.6 30.7 41.4 21.4 27.1 27.7 11.2 18.5 40.8 23.7 15.6 19.5 46.6 15.3 13.6 27.7 35.6 15.6 28.9 40.3 21.5 17.7 95.3 79.6 51.4 84.1 48.8 58.0 52.9 78.5 86.0 77.1 103.2 69.4 141.4 46.2 133.4 82.6 101.3 54.5 0.0 94.3 90.3 97.4 42.1 72.9 60.7 67.9 95.4 54.2 65.9 69.0 85.9 95.7 108.6 58.9 62.9 57.1 87.0 61.7 87.4 99.5 27.9 0.7 63.4 38.7 92.7 9.8 63.8 106.2 83.3 112.6 71.0 67.9 90.4 48.2 99.4 35.9 90.9 58.3 72.4 46.1 73.9 58.9 100.9 62.6 117.3 85.9 63.2 29.6 96.7 33.2 56.4 20.2 34.7 70.5 38.7 41.6 38.3 39.9 51.4 33.9 46.0 32.1 11.3 58.8 57.8 41.2 55.9 39.4 13.5 14.7 14.4 17.2 12.8 15.2 14.1 13.7 14.6 15.6 13.6 17.7 26.8 57.7 37.1 4.9 39.4 86.8 122.1 58.1 60.3 25.7 45.2 33.4 21.2 35.8 53.2 42.3 8.4 71.9 34.6 79.9 135.0 70.8 23.3 35.6 40.3 25.7 55.2 29.2 3.9 61.3 62.9 50.0 57.1 40.9 23.5 35.4 25.7 40.4 73.4 40.4 4.3 74.0 42.7 40.8 30.5 24.5 46.3 40.5 40.9 2.8 33.8 59.3 44.3 4.5 8.7 75.2 116.1 42.2 41.9 108.6 73.2 93.0 37.0 20.8 26.3 28.2 37.6 18.7 12.3 78.6 82.7 47.5 34.9 45.7 82.8 152.6 SMIM31 LINC01207 ENSG00000248771 "Small integral membrane protein 31" A0A1B0GVY4 4 164754064-164803795 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "gallbladder: 7.8;intestine: 24.6;prostate: 11.0" "Group enriched" "Detected in some" 5 "Exocrine glandular cells: 93.3;Pancreatic endocrine cells: 139.7" "Cancer enhanced" "Detected in many" "prostate cancer: 8.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted - unknown location" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (2.84e-1)" "unprognostic (1.18e-1)" "unprognostic (2.47e-2)" "unprognostic (1.87e-4)" "unprognostic (2.95e-2)" "unprognostic (1.78e-1)" "unprognostic (4.17e-2)" "unprognostic (4.82e-1)" "unprognostic (9.47e-2)" "unprognostic (5.63e-3)" 0.1 0.1 0.3 1.4 0.3 1.0 1.0 0.6 0.5 5.0 0.3 15.4 22.0 0.3 0.9 0.1 0.1 7.8 0.1 0.3 0.1 0.1 0.1 0.4 0.3 0.4 0.2 0.1 0.4 0.1 0.0 0.1 0.4 11.0 15.5 0.2 1.2 0.1 0.2 0.2 24.6 0.7 0.1 0.1 0.6 0.1 0.4 0.0 0.1 0.0 0.1 1.7 0.0 0.9 0.1 0.8 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.1 0.3 0.1 0.4 0.0 0.1 0.0 0.3 1.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.1 0.4 0.1 0.1 0.1 0.2 0.3 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.6 0.3 0.1 0.3 0.0 0.0 0.3 0.3 0.6 0.5 0.3 0.1 0.4 0.2 0.4 0.1 0.4 0.9 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 1.1 0.0 0.0 9.3 3.7 0.0 0.1 0.0 0.0 0.0 3.8 0.0 2.5 2.2 0.3 0.0 0.0 0.0 93.3 0.0 0.2 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.7 0.0 0.0 0.0 0.0 0.0 0.8 10.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 SMIM36 ENSG00000261873 "Small integral membrane protein 36" A0A1B0GVT2 17 55448433-55511444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "retina: 6.6" "Cell type enhanced" "Detected in single" "Club cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (2.07e-1)" 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SMIM43 ENSG00000164112 "Small integral membrane protein 43" Q4W5P6 4 121758881-121765427 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "brain: 8.3" "Group enriched" "Detected in some" 9 "Cytotrophoblasts: 16.7;Syncytiotrophoblasts: 4.5" "Low cancer specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basal ganglia: 8.3;cerebral cortex: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "MOLT-4: 3.2" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" NA NA "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (9.67e-3)" "unprognostic (3.25e-3)" "unprognostic (3.13e-2)" "unprognostic (1.09e-1)" "unprognostic (1.61e-1)" "unprognostic (5.73e-3)" "unprognostic (3.63e-2)" "unprognostic (1.49e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-3)" "unprognostic (4.40e-3)" "unprognostic (1.38e-1)" "unprognostic (3.82e-7)" "unprognostic (1.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.02e-2)" "unprognostic (2.04e-1)" 0.0 0.0 0.4 0.0 8.3 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 8.3 0.0 2.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 SMOC1 ENSG00000198732 "SPARC related modular calcium binding 1" Q9H4F8 14 69854131-70032366 "Disease related genes, Human disease related genes, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.2;liver: 67.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 104.4;Oligodendrocyte precursor cells: 372.4;Oligodendrocytes: 81.1;Peritubular cells: 133.2" "Cancer enhanced" "Detected in many" "glioma: 27.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cell line enhanced" "Detected in some" "AF22: 50.3;HeLa: 122.6;HSkMC: 38.3;SiHa: 72.1;SK-BR-3: 30.6;U-266/70: 42.3;U-87 MG: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004153, CAB034427" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 140000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "CAB034427: AB_2193382, HPA004153: AB_1080035" "unprognostic (3.31e-1)" "unprognostic (2.17e-3)" "unprognostic (8.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.89e-2)" "unprognostic (4.04e-1)" "unprognostic (6.75e-3)" "unprognostic (2.09e-3)" "unprognostic (4.76e-2)" "unprognostic (2.80e-2)" "unprognostic (5.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.09e-2)" "unprognostic (3.92e-1)" "unprognostic (2.57e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" 15.9 10.3 29.2 0.5 30.3 0.1 6.2 53.2 29.1 9.4 17.5 1.3 1.9 2.2 7.7 0.3 6.6 0.5 8.3 27.9 31.6 3.0 67.9 0.6 0.9 38.4 38.8 1.4 10.3 0.3 4.4 8.0 36.8 33.4 1.0 2.4 5.8 38.8 12.7 2.4 1.4 1.0 41.2 27.2 3.8 35.7 29.6 0.4 4.2 2.7 0.5 1.3 6.3 52.8 0.0 3.3 50.3 0.0 9.8 6.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 2.9 0.0 0.0 20.4 0.0 122.6 17.4 0.1 0.0 0.0 38.3 11.9 1.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.0 0.2 72.1 30.6 0.0 0.3 0.0 0.0 0.4 0.3 2.9 0.0 0.0 42.3 0.0 0.0 51.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 29.2 30.3 53.2 29.1 27.9 31.6 38.4 38.8 36.8 41.2 29.6 52.8 0.3 0.0 0.0 12.1 2.5 0.3 0.0 0.7 0.0 2.1 1.3 3.8 2.0 7.2 0.1 0.0 16.7 24.2 4.0 0.0 0.0 0.3 4.7 11.9 0.6 2.9 15.6 0.0 1.0 2.3 0.8 6.0 3.6 1.5 0.0 1.4 3.3 104.4 2.8 0.0 13.5 0.1 14.2 2.5 0.4 19.0 7.8 0.3 0.0 1.0 0.1 0.3 0.0 372.4 81.1 3.7 0.1 133.2 12.4 0.0 0.0 0.0 1.1 0.3 0.0 0.7 2.3 2.1 3.9 0.0 0.4 40.2 0.4 0.4 0.0 0.1 SMOC2 SMAP2 ENSG00000112562 "SPARC related modular calcium binding 2" Q9H3U7 6 168441151-168673445 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 149.8;Leydig cells: 321.8;Peritubular cells: 769.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.1;EFO-21: 2.8;RPMI-8226: 11.3;RPTEC TERT1: 3.8;SuSa: 9.1" "Region enhanced" "Detected in many" "hippocampal formation: 25.7" "Region enhanced" "Detected in single" "spinal cord: 1.4" "Secreted to extracellular matrix" NA NA 120000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.23e-1)" "unprognostic (5.29e-2)" "unprognostic (3.70e-2)" "unprognostic (1.53e-2)" "unprognostic (2.43e-2)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (4.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.16e-6)" "unprognostic (3.50e-2)" "unprognostic (2.68e-1)" "unprognostic (6.35e-2)" "unprognostic (6.20e-3)" 67.8 14.0 10.6 13.0 12.7 0.0 61.0 10.8 16.2 82.1 42.3 44.1 21.4 164.0 147.2 53.1 119.6 100.8 57.2 10.6 11.3 13.0 4.0 14.7 14.7 11.8 11.8 124.1 25.2 12.2 4.5 18.8 11.9 31.0 24.9 2.8 17.1 54.6 42.1 28.9 27.8 76.5 10.2 4.4 144.7 44.2 12.2 10.9 43.5 54.8 11.1 68.7 21.8 10.0 2.4 0.0 8.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.4 1.0 0.0 0.0 0.0 0.0 11.3 3.8 0.0 1.7 0.3 0.0 0.3 0.1 9.1 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 12.7 10.8 16.2 10.6 11.3 11.8 11.8 11.9 10.2 12.2 10.0 8.1 0.0 1.7 0.7 0.0 11.1 8.0 0.0 1.2 7.1 12.5 12.1 7.7 0.0 1.8 11.0 0.0 2.5 0.0 3.6 0.0 0.0 2.6 40.3 42.3 11.0 19.7 0.0 0.5 0.0 1.7 149.8 1.1 58.4 0.0 17.2 3.3 0.0 1.2 0.0 9.7 4.5 0.0 0.0 3.9 17.2 321.8 2.9 3.6 6.5 0.0 0.4 0.0 2.0 0.1 0.1 0.4 769.2 0.1 6.7 2.0 0.0 2.2 0.8 46.0 14.7 63.3 3.9 5.1 0.8 2.7 2.6 1.7 17.3 47.4 1.1 SMPD1 ASM ENSG00000166311 "Sphingomyelin phosphodiesterase 1" P17405 11 6390440-6394998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Neurodegeneration, Niemann-Pick disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 131.3;Late spermatids: 200.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 139.1;fHDF/TERT166: 144.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2700000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (8.76e-2)" "unprognostic (2.66e-1)" "unprognostic (6.99e-2)" "unprognostic (2.28e-3)" "prognostic unfavorable (7.72e-5)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (4.90e-2)" "unprognostic (8.06e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.47e-4)" "unprognostic (4.35e-2)" "prognostic favorable (4.57e-6)" "unprognostic (4.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" "unprognostic (1.71e-1)" 21.8 36.5 38.8 13.9 44.7 7.3 20.1 45.1 43.0 21.2 33.9 25.3 16.8 20.9 14.4 20.6 14.6 21.5 55.8 39.1 43.0 73.7 95.3 31.3 14.6 42.7 42.6 17.9 32.8 34.2 41.9 21.6 43.3 29.4 14.9 8.5 29.0 20.0 37.9 37.9 23.8 17.6 40.9 21.1 25.4 14.0 47.5 17.8 34.0 29.4 11.0 23.6 21.0 46.8 16.4 13.1 10.1 26.5 139.1 72.2 17.1 60.4 95.0 27.7 33.0 22.0 11.9 4.7 27.4 144.0 59.3 7.4 8.4 12.7 13.0 21.0 9.6 5.1 19.5 6.0 62.3 3.7 37.4 96.0 23.4 25.9 17.7 100.9 61.6 1.7 9.1 30.5 58.9 17.0 0.1 6.5 3.9 23.2 22.3 1.2 5.5 7.0 23.9 6.2 17.0 9.7 27.6 19.5 38.5 12.9 7.3 7.0 53.9 103.0 10.9 59.1 15.4 37.6 44.0 3.5 93.7 10.8 47.1 1.9 2.5 3.4 6.4 2.1 5.0 1.5 5.5 5.0 1.3 3.1 10.0 10.1 2.5 6.6 0.6 1.7 4.7 3.2 38.8 44.7 45.1 43.0 39.1 43.0 42.7 42.6 43.3 40.9 47.5 46.8 14.1 25.6 14.4 10.7 12.2 7.9 22.8 15.3 6.8 12.6 13.7 9.0 37.7 24.3 12.8 25.8 25.0 38.8 11.5 131.3 11.7 53.4 50.0 6.2 13.0 18.6 23.8 9.9 5.8 38.2 14.4 31.4 15.8 21.0 10.8 9.4 26.7 88.5 34.1 20.2 5.5 20.3 24.4 15.5 6.2 200.7 11.5 15.8 55.2 4.7 7.8 16.4 36.0 6.6 15.5 24.7 83.1 13.5 23.1 26.0 51.7 75.1 2.4 5.2 0.0 8.9 17.1 1.4 3.1 7.5 8.0 34.3 23.3 10.2 18.0 15.4 SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358327-68448508 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 61.5;lymphoid tissue: 52.0" "Cell type enhanced" "Detected in many" "dendritic cells: 77.1;Gastric mucus-secreting cells: 70.8;Horizontal cells: 301.2;Proximal enterocytes: 115.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 29.7;cerebral cortex: 24.9;hippocampal formation: 25.4" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 138.9" "Lineage enriched" "Detected in many" 7 "dendritic cells: 138.9" "Cell line enhanced" "Detected in some" "HMC-1: 9.7;MOLT-4: 14.7;RPMI-8226: 12.4;SCLC-21H: 13.4" "Region enhanced" "Detected in all" "basal ganglia: 115.2" "Region enhanced" "Detected in all" "basal ganglia: 67.7" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favorable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" 6.8 2.1 8.0 3.6 29.7 1.8 2.8 1.8 24.9 2.7 0.1 13.8 61.5 1.4 0.1 2.1 3.8 9.0 1.5 25.4 0.5 4.0 7.4 2.5 4.2 0.0 0.2 4.8 2.6 0.1 16.5 0.2 0.6 4.6 6.9 6.5 3.0 0.3 2.4 13.6 57.7 0.7 0.5 3.4 23.2 8.6 5.1 52.0 2.7 0.0 1.9 1.7 2.5 2.3 0.3 0.8 0.4 0.1 0.0 0.0 5.5 0.4 0.0 0.4 0.1 3.1 1.0 0.4 0.6 0.3 0.2 1.2 0.0 0.0 0.1 0.3 0.7 0.1 2.7 0.3 0.0 0.0 9.7 0.0 0.0 0.0 0.2 0.5 0.0 0.9 0.9 0.3 0.3 0.2 14.7 2.8 0.6 4.9 0.1 0.7 0.2 12.4 0.0 0.1 13.4 2.7 0.4 1.6 0.7 0.2 1.1 0.9 0.0 0.4 0.8 1.4 0.1 2.3 1.2 0.3 0.2 0.9 0.2 4.4 0.0 20.7 2.3 0.1 0.3 1.7 0.2 0.6 0.1 0.9 0.6 0.3 0.1 0.1 0.0 138.9 1.9 1.2 8.0 29.7 1.8 24.9 25.4 0.5 0.0 0.2 0.6 0.5 5.1 2.3 0.3 3.2 1.1 1.0 2.6 0.1 1.5 0.6 0.0 50.8 1.8 0.6 2.9 15.7 1.5 0.0 0.0 0.0 77.1 44.7 0.0 1.3 8.5 3.0 0.3 0.6 25.8 0.4 33.8 0.9 0.1 5.2 70.8 0.5 0.0 0.2 0.7 9.4 0.3 301.2 20.4 34.7 2.0 1.0 0.5 18.6 15.2 2.9 0.0 1.9 0.6 0.9 1.0 10.6 1.7 1.6 39.9 45.9 2.5 3.6 115.1 0.0 14.6 3.9 0.0 0.2 0.3 10.0 2.1 0.1 1.0 0.0 6.2 0.2 21.6 5.4 SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 156.3;Distal enterocytes: 291.5;Paneth cells: 157.5;Proximal enterocytes: 383.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 80.9" "Lineage enriched" "Detected in many" 11 "granulocytes: 80.9" "Cell line enhanced" "Detected in many" "ASC diff: 44.2;hTCEpi: 36.9;OE19: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" No No 26000000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 15.0 23.3 4.6 18.7 5.1 22.9 23.7 8.2 9.4 72.8 8.9 60.7 45.5 13.3 6.5 13.6 7.9 17.2 5.6 5.3 5.7 47.4 80.0 14.1 21.4 5.9 5.4 9.1 20.8 32.4 7.5 44.0 5.9 21.8 65.7 6.0 13.7 16.6 39.8 64.5 77.3 8.5 5.7 27.0 30.5 2.9 5.4 5.1 9.1 55.8 16.2 35.5 30.9 7.7 0.3 2.6 6.1 2.8 44.2 19.9 19.5 10.4 27.8 3.1 6.6 3.3 2.7 0.0 1.4 6.6 8.2 4.9 1.7 5.3 2.6 0.0 5.4 2.5 9.8 9.0 28.3 0.0 0.1 24.4 36.9 3.0 5.3 12.0 5.5 0.0 3.8 0.0 12.7 9.3 0.0 0.2 1.1 58.8 8.0 0.0 10.8 0.4 15.1 4.2 4.4 0.1 1.5 18.5 27.9 3.9 3.1 1.4 11.0 5.9 3.5 0.6 6.8 0.0 0.0 0.0 8.7 4.9 13.7 80.9 4.0 1.1 0.0 4.3 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 1.3 0.0 7.5 0.0 0.0 1.4 4.6 5.1 8.2 9.4 5.3 5.7 5.9 5.4 5.9 5.7 5.4 7.7 11.8 3.2 17.8 5.2 2.4 53.7 24.5 13.7 15.9 3.0 12.2 6.6 4.0 25.8 9.7 5.5 4.2 156.3 0.4 291.5 56.7 24.6 0.2 4.2 12.6 7.1 48.7 5.7 7.4 25.7 40.4 46.3 34.7 5.2 10.1 0.8 18.9 77.8 62.7 3.3 10.5 61.7 59.0 126.3 10.0 1.2 15.5 33.4 35.6 11.2 9.9 11.5 2.1 11.1 11.0 19.5 157.5 14.3 0.9 16.7 383.1 129.3 7.5 6.2 13.1 12.8 9.9 1.1 3.7 15.5 76.0 115.1 2.0 11.4 38.9 16.6 SMPDL3B ASML3B ENSG00000130768 "Sphingomyelin phosphodiesterase acid like 3B" Q92485 1 27935000-27959157 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.1;pancreas: 49.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.1;Ductal cells: 31.5;Paneth cells: 47.5;Proximal enterocytes: 37.4;Undifferentiated cells: 31.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 6 "eosinophil: 3.3;myeloid DC: 1.3;neutrophil: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.3;granulocytes: 3.3" "Cell line enhanced" "Detected in many" "BEWO: 46.0;CAPAN-2: 35.3;NTERA-2: 27.6;RPMI-8226: 30.1;SK-BR-3: 45.9;T-47d: 33.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA030561 Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 400000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Golgi apparatus" "HPA030561: AB_10604095" "unprognostic (1.22e-2)" "unprognostic (4.45e-1)" "unprognostic (4.58e-3)" "unprognostic (3.83e-2)" "unprognostic (3.35e-3)" "unprognostic (2.96e-2)" "unprognostic (1.50e-1)" "unprognostic (2.68e-1)" "unprognostic (3.95e-1)" "unprognostic (6.02e-2)" "unprognostic (1.64e-1)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (2.40e-1)" "unprognostic (1.48e-1)" "unprognostic (4.40e-2)" "unprognostic (3.09e-3)" 1.5 0.3 0.5 2.2 0.6 2.0 5.7 2.5 0.6 2.8 2.0 22.2 24.1 1.9 15.8 1.1 7.0 2.2 0.3 1.1 0.7 5.2 0.4 6.6 1.2 0.4 0.4 0.2 49.4 7.9 1.0 0.3 0.5 3.6 23.6 0.1 12.5 0.5 0.0 0.9 14.2 1.0 0.6 1.7 16.5 0.7 0.8 0.5 13.9 0.0 3.1 2.2 0.4 0.6 5.4 2.5 0.0 0.3 0.0 0.0 46.0 0.0 1.1 0.6 3.4 12.1 35.3 1.7 8.3 0.0 0.7 5.9 3.8 3.2 0.5 0.0 23.6 7.9 0.5 3.0 0.0 2.6 0.0 0.2 2.9 7.0 0.4 1.0 1.0 0.3 1.0 0.4 0.0 19.5 0.1 0.8 27.6 4.1 4.3 0.5 0.2 30.1 24.6 9.5 23.4 0.5 0.0 45.9 1.3 4.7 33.3 1.4 0.0 0.0 7.6 0.1 0.0 0.3 12.9 0.6 0.8 0.0 0.1 0.1 0.1 3.3 0.0 0.1 0.0 0.2 0.0 0.0 1.3 0.2 0.1 0.0 1.8 0.3 0.0 0.0 0.0 0.1 0.5 0.6 2.5 0.6 1.1 0.7 0.4 0.4 0.5 0.6 0.8 0.6 0.1 9.6 17.9 0.0 2.3 0.1 2.7 4.0 0.0 0.0 15.0 6.5 0.4 1.5 13.8 9.2 0.0 2.5 0.5 38.1 0.0 31.5 0.4 2.2 0.3 1.1 20.4 1.3 0.8 23.3 0.2 0.2 18.3 5.6 0.0 2.0 0.4 0.0 0.3 0.0 0.1 21.6 10.2 0.0 0.4 0.2 0.0 0.9 0.0 1.0 0.0 0.0 0.0 1.0 0.0 21.7 47.5 0.0 16.6 3.7 37.4 8.7 2.7 0.0 0.0 0.0 0.8 0.0 0.2 0.6 0.1 7.7 0.8 0.1 31.2 3.0 SMR3A "PBI, PRL5, PROL5" ENSG00000109208 "Submaxillary gland androgen regulated protein 3A" Q99954 4 70360760-70367158 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 59 "salivary gland: 59.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 0.7;liver cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044567 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Mammary glandular cells - Lactation" "HPA044567: AB_10796114" "unprognostic (2.06e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 59.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMR3B "P-B, PRL3, PROL3" ENSG00000171201 "Submaxillary gland androgen regulated protein 3B" P02814 4 70370093-70390244 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 946 "salivary gland: 217144.9" "Group enriched" "Detected in some" 55 "Breast glandular cells: 2.3;Early spermatids: 8.4;Late spermatids: 6.0" "Cancer enriched" "Detected in some" 22 "breast cancer: 32.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 39 "EFO-21: 4.5" "Secreted to digestive system" NA NA 1900000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 38: EFO-21 - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (3.72e-1)" 0.0 9.1 0.0 0.0 0.0 7.6 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.1 8.9 0.0 0.0 44.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 47.3 229.5 0.0 1.6 23.2 0.0 1.6 0.0 0.0 217144.9 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 2.1 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SNAPIN "BLOC1S7, BORCS3, SNAPAP" ENSG00000143553 "SNAP associated protein" O95295 1 153658703-153661852 "Predicted intracellular proteins, Transporters" "Exocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046974 Approved Approved "Nucleoli,Golgi apparatus" NA NA 20000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" Nucleoli "HPA046974: AB_10962506" "unprognostic (3.65e-1)" "unprognostic (1.67e-1)" "unprognostic (1.47e-1)" "unprognostic (5.66e-2)" "unprognostic (1.75e-1)" "unprognostic (2.06e-1)" "unprognostic (1.64e-3)" "unprognostic (1.54e-1)" "unprognostic (4.86e-2)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (5.42e-4)" "unprognostic (2.31e-1)" "unprognostic (4.73e-1)" "unprognostic (1.31e-3)" "unprognostic (4.89e-2)" 34.6 50.8 41.5 18.5 42.9 13.1 30.3 44.3 43.0 23.9 38.7 35.7 12.8 30.7 34.1 35.1 27.5 21.7 63.7 39.9 43.5 37.8 32.1 21.0 27.4 43.1 42.3 24.0 17.5 41.2 16.4 19.0 42.9 24.4 20.2 25.1 22.1 29.4 91.5 27.9 23.2 30.4 44.5 30.9 26.3 19.2 43.0 30.6 25.5 77.0 31.9 31.1 23.5 45.1 50.8 60.6 51.5 31.0 63.2 42.7 32.4 41.7 46.1 57.8 43.9 43.9 39.3 35.8 82.6 42.9 29.0 65.6 42.5 54.4 40.9 49.3 57.4 39.6 41.3 21.1 65.4 39.3 24.4 50.5 41.1 43.6 49.0 61.0 54.8 41.7 34.7 27.8 59.5 82.7 46.0 23.9 27.5 78.6 64.7 42.9 44.1 96.8 65.0 47.6 38.9 67.8 48.0 55.0 57.8 50.3 84.0 43.5 48.4 27.2 40.5 54.4 40.0 65.6 77.4 56.0 51.4 24.9 36.1 106.2 146.9 139.7 86.8 154.1 100.6 130.1 88.2 88.9 153.5 119.6 96.9 87.9 30.4 118.1 126.8 115.6 136.3 146.6 41.5 42.9 44.3 43.0 39.9 43.5 43.1 42.3 42.9 44.5 43.0 45.1 41.7 19.2 16.6 7.2 31.6 20.6 35.1 88.7 35.9 14.2 39.1 44.4 39.8 40.0 45.3 29.5 8.4 64.4 35.9 18.0 74.3 71.4 9.6 31.5 24.2 34.9 13.8 33.6 5.9 65.2 49.5 31.2 16.3 25.6 30.4 31.9 40.7 35.1 90.2 21.9 6.5 20.0 40.7 48.3 21.8 26.6 30.7 34.7 26.6 4.7 76.5 84.8 59.8 8.0 14.4 53.5 25.5 49.7 23.8 34.7 26.6 76.7 40.9 21.7 46.0 25.3 39.7 29.3 42.6 45.5 23.4 73.7 26.9 44.2 24.6 36.2 SNED1 "FLJ00133, Snep, SST3" ENSG00000162804 "Sushi, nidogen and EGF like domains 1" Q8TER0 2 240998618-241095568 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 95.0;Excitatory neurons: 86.0;Leydig cells: 95.1;Microglial cells: 77.8;Peritubular cells: 71.1;Skeletal myocytes: 53.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "ASC TERT1: 410.4;HSkMC: 211.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036414, HPA036415" Uncertain "Secreted to blood" NA NA 27000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA036414: AB_10960852, HPA036415: AB_10964128" "unprognostic (1.41e-1)" "unprognostic (3.92e-2)" "unprognostic (1.52e-2)" "unprognostic (9.37e-3)" "unprognostic (1.57e-3)" "unprognostic (4.62e-2)" "unprognostic (7.77e-4)" "unprognostic (3.49e-2)" "unprognostic (4.96e-1)" "unprognostic (7.85e-3)" "unprognostic (3.42e-2)" "unprognostic (2.06e-2)" "unprognostic (2.80e-2)" "unprognostic (1.16e-1)" "unprognostic (3.72e-1)" "unprognostic (5.51e-3)" "unprognostic (4.95e-3)" 23.8 9.3 4.2 6.4 8.5 1.2 15.8 14.1 6.9 34.1 32.4 7.3 4.5 18.0 11.8 6.1 21.6 18.7 11.1 10.7 11.7 7.1 8.0 13.3 4.7 8.3 6.4 21.9 7.3 3.1 7.2 1.9 4.8 12.5 3.4 2.5 14.6 7.5 19.8 12.1 10.4 6.3 0.6 14.1 5.7 9.3 2.2 3.3 30.2 9.1 2.9 11.5 10.7 5.9 0.1 0.6 0.4 4.8 61.1 410.4 0.3 2.4 1.5 0.5 0.2 0.2 0.2 0.1 1.0 4.4 0.5 0.2 0.4 0.0 0.3 2.7 1.0 0.2 4.5 0.4 2.6 0.2 0.5 211.6 0.1 0.5 0.3 28.4 9.5 0.2 0.1 2.7 11.5 2.4 1.6 0.2 0.7 0.1 0.3 0.2 8.1 0.1 5.6 0.5 0.8 0.3 1.9 8.3 4.2 0.6 1.8 0.8 23.7 8.7 0.6 50.9 1.5 0.8 0.4 1.5 11.7 0.1 2.6 0.0 0.0 0.0 0.0 0.3 0.3 1.9 0.4 0.2 0.0 0.6 0.2 0.2 0.0 0.0 0.7 0.0 0.4 0.0 4.2 8.5 14.1 6.9 10.7 11.7 8.3 6.4 4.8 0.6 2.2 5.9 8.0 6.4 11.0 95.0 8.4 3.6 0.9 0.4 2.8 2.8 1.1 1.8 2.4 1.5 8.5 5.5 0.0 0.1 0.3 0.3 0.0 1.2 1.3 10.6 16.8 10.9 2.4 3.2 86.0 1.2 0.1 22.1 2.6 10.7 0.0 5.0 22.9 5.8 0.2 1.7 32.5 0.2 0.0 2.9 5.9 5.9 95.1 2.7 1.8 77.8 0.6 7.4 0.0 11.6 7.0 0.7 0.1 71.1 0.9 3.0 0.0 0.5 4.2 1.2 26.3 53.7 4.9 0.6 1.5 0.7 2.6 0.4 1.8 36.4 0.5 0.6 SNORC "ASCL830, C2orf82, UNQ830" ENSG00000182600 "Secondary ossification center associated regulator of chondrocyte maturation" Q6UX34 2 232857270-232878708 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 55.0;breast: 14.2;skin 1: 32.2" "Group enriched" "Detected in some" 22 "Breast glandular cells: 367.0;Breast myoepithelial cells: 324.9" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "basophil: 2.8" "Lineage enriched" "Detected in single" 20 "granulocytes: 2.8" "Cell line enriched" "Detected in some" 13 "Hep G2: 59.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052824 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA052824: AB_2681964" "unprognostic (4.58e-3)" "unprognostic (1.31e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "unprognostic (3.06e-1)" "unprognostic (4.71e-1)" "unprognostic (1.23e-3)" "unprognostic (3.52e-1)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (4.30e-7)" "unprognostic (1.83e-3)" "unprognostic (8.15e-2)" "unprognostic (1.58e-2)" "unprognostic (1.33e-2)" 1.3 0.9 6.7 0.2 14.1 0.5 14.2 21.2 8.5 0.7 0.2 3.3 0.9 0.7 0.5 1.0 1.2 0.0 0.8 11.9 23.5 1.3 7.4 0.8 0.6 37.8 14.8 0.7 1.7 0.3 1.6 0.2 28.3 1.5 0.3 0.6 4.7 0.1 1.0 32.2 1.7 0.1 38.2 1.1 0.8 8.1 14.2 0.1 0.6 0.0 0.0 0.9 0.8 55.0 0.9 0.0 0.3 1.4 1.0 1.6 2.4 0.3 0.0 0.3 0.7 0.0 0.2 0.0 0.7 0.1 0.5 0.5 0.0 0.0 0.0 0.6 2.1 0.5 0.4 59.6 0.8 0.1 1.7 0.0 1.3 0.4 0.8 0.7 1.6 0.6 0.1 0.2 0.2 0.2 0.2 0.5 0.0 0.0 2.2 0.4 0.6 0.4 0.1 0.9 0.2 0.8 0.4 0.0 2.2 1.0 0.1 2.6 0.9 0.2 0.8 0.8 0.8 3.8 4.7 0.2 0.1 1.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 14.1 21.2 8.5 11.9 23.5 37.8 14.8 28.3 38.2 14.2 55.0 3.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 367.0 324.9 0.0 0.0 0.0 1.8 0.0 0.1 10.1 0.0 5.9 0.5 0.0 3.8 0.4 6.3 0.0 0.0 0.0 0.8 0.1 2.9 0.0 2.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 2.3 0.9 0.0 0.0 SNTB1 "59-DAP, A1B, BSYN2, SNT2, SNT2B1, TIP-43" ENSG00000172164 "Syntrophin beta 1" Q13884 8 120535745-120813273 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.3" "Cell type enhanced" "Detected in many" "Astrocytes: 70.2;Hepatocytes: 66.8;Microglial cells: 45.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 84.9;OE19: 78.5;U-266/70: 77.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024659 Uncertain "Intracellular and membrane" NA NA 25000 "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA024659: AB_1857713" "unprognostic (1.32e-1)" "unprognostic (2.77e-2)" "unprognostic (6.12e-2)" "unprognostic (1.42e-1)" "unprognostic (6.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (6.41e-3)" "unprognostic (2.07e-1)" "unprognostic (3.88e-1)" "unprognostic (1.31e-1)" "unprognostic (4.72e-1)" "unprognostic (2.00e-2)" "unprognostic (5.08e-2)" "unprognostic (5.88e-2)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" 7.9 66.4 7.5 5.5 6.5 18.9 8.0 5.8 5.9 5.6 42.9 6.2 5.7 4.4 2.7 8.4 6.0 4.3 4.9 6.1 11.8 12.6 89.3 15.4 7.3 7.2 11.4 2.5 45.0 1.4 2.6 8.6 7.8 4.8 6.4 4.8 34.8 3.4 28.2 9.8 6.3 3.1 6.0 11.9 24.1 9.8 9.1 3.4 61.4 32.4 3.5 3.9 3.6 6.5 0.1 1.8 0.7 0.0 11.3 22.9 0.1 6.0 36.7 1.8 2.7 12.0 1.6 0.0 10.7 6.8 0.0 0.1 2.0 0.0 1.3 5.6 6.5 0.0 0.3 84.9 1.2 16.9 0.0 11.4 0.0 10.1 0.0 14.9 0.4 10.4 0.0 32.3 5.9 3.3 0.0 13.7 2.1 78.5 8.7 0.0 43.8 0.1 34.4 2.0 0.1 0.4 2.4 12.5 30.2 0.7 1.5 30.5 0.0 23.7 1.4 0.0 2.0 77.2 33.0 34.8 18.4 49.0 26.7 1.8 0.8 2.7 2.2 0.4 0.5 0.5 0.4 1.1 0.6 0.2 1.1 1.1 0.1 1.6 0.3 0.0 0.0 0.6 7.5 6.5 5.8 5.9 6.1 11.8 7.2 11.4 7.8 6.0 9.1 6.5 1.9 12.8 27.2 70.2 4.7 0.4 0.7 0.9 1.8 2.4 8.5 6.0 2.0 2.8 9.0 5.5 2.1 0.8 8.4 1.3 9.8 1.5 9.3 2.4 5.8 4.2 0.0 14.1 2.4 10.9 2.2 9.8 11.2 6.2 1.3 8.8 13.2 66.8 11.3 0.0 3.1 3.9 16.2 29.9 4.3 4.2 4.7 18.1 1.8 45.9 12.1 16.0 18.6 2.5 12.2 4.3 1.9 13.2 2.8 1.1 0.1 3.3 13.8 0.7 13.1 3.9 14.3 1.1 0.2 10.1 1.0 0.3 12.0 11.0 4.1 0.6 SNTB2 "D16S2531E, EST25263, SNT2B2, SNT3, SNTL" ENSG00000168807 "Syntrophin beta 2" Q13425 16 69187129-69309052 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.4;Muller glia cells: 214.1;Rod photoreceptor cells: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SiHa: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001394 Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA001394: AB_1080170" "unprognostic (4.86e-1)" "unprognostic (3.26e-2)" "unprognostic (2.77e-2)" "unprognostic (8.07e-3)" "unprognostic (6.46e-2)" "unprognostic (9.68e-2)" "unprognostic (1.89e-2)" "unprognostic (5.50e-2)" "unprognostic (1.22e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-2)" "unprognostic (3.64e-2)" "unprognostic (5.77e-3)" "unprognostic (1.71e-2)" "unprognostic (7.43e-2)" "unprognostic (1.73e-2)" "unprognostic (1.88e-1)" 11.0 5.0 3.3 5.2 3.9 2.7 8.8 1.0 6.7 11.0 10.1 6.7 3.7 10.4 5.1 7.0 8.7 7.1 5.3 4.6 0.8 6.7 3.8 8.6 5.6 2.5 0.9 6.2 4.1 12.4 4.0 5.2 0.9 8.2 5.3 21.6 5.2 5.5 5.7 8.5 6.0 8.7 0.6 5.7 6.1 7.1 1.5 5.8 10.5 3.8 4.9 8.7 8.7 3.7 7.2 10.9 7.4 5.8 26.6 35.6 9.1 13.9 19.3 10.7 11.8 10.7 6.5 9.0 8.3 16.2 5.6 12.9 10.0 6.8 13.9 4.0 5.5 4.0 11.1 9.2 8.8 0.3 5.9 25.6 4.9 17.6 7.1 11.1 32.4 2.5 2.3 13.8 13.1 8.2 3.0 1.4 5.0 4.2 8.6 18.1 6.5 16.8 5.7 10.9 2.8 6.1 42.6 6.0 4.4 5.5 7.1 0.5 25.4 20.0 9.6 14.2 13.0 3.1 5.2 10.0 12.8 1.4 9.3 0.4 0.2 0.3 0.9 0.3 0.9 0.2 0.4 0.5 0.2 0.2 0.2 1.1 0.9 0.7 0.3 0.1 0.5 0.3 3.3 3.9 1.0 6.7 4.6 0.8 2.5 0.9 0.9 0.6 1.5 3.7 55.9 19.2 11.7 36.6 9.0 38.0 28.0 17.1 70.0 33.2 19.0 25.0 9.2 10.0 10.4 27.6 41.7 9.5 33.7 29.0 3.9 9.7 25.9 20.6 61.3 81.4 10.3 4.8 151.4 24.1 7.9 53.1 20.9 28.7 1.3 15.8 126.7 11.1 6.9 5.0 62.6 16.6 8.2 33.1 29.3 27.5 59.0 12.9 30.2 33.7 8.6 214.1 47.4 30.7 27.9 16.3 32.8 65.1 20.7 40.9 12.7 34.5 10.0 136.7 6.6 26.0 35.6 27.9 15.4 30.7 38.8 3.7 32.8 20.2 19.6 28.7 SNX31 MGC39715 ENSG00000174226 "Sorting nexin 31" Q8N9S9 8 100572889-100663415 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 6.5;urinary bladder: 16.4" "Cell type enriched" "Detected in some" 4 "Early spermatids: 81.8" "Cancer enriched" "Detected in many" 22 "urothelial cancer: 24.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 49 "RT4: 80.7" "Region enriched" "Detected in single" 5 "thalamus: 2.6" "Not detected" "Not detected" "HPA024284, HPA053466" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" Cytosol "HPA024284: AB_1853894, HPA053466: AB_2682161" "unprognostic (1.39e-1)" "unprognostic (3.83e-2)" "unprognostic (7.99e-2)" "unprognostic (1.52e-1)" "unprognostic (7.20e-5)" "unprognostic (1.04e-1)" "unprognostic (1.01e-2)" "unprognostic (2.44e-2)" "unprognostic (1.02e-1)" "unprognostic (2.21e-1)" "unprognostic (2.09e-2)" "unprognostic (1.69e-1)" "unprognostic (7.79e-3)" "unprognostic (1.66e-1)" "prognostic favorable (1.47e-4)" "unprognostic (2.54e-1)" "unprognostic (4.05e-2)" 0.6 0.1 1.0 0.0 1.2 0.2 0.4 0.8 3.1 0.4 0.6 0.3 0.0 0.3 0.2 6.5 0.3 1.1 1.7 1.0 1.1 0.2 0.5 0.1 0.4 0.0 0.0 0.4 0.3 0.3 0.2 0.0 0.0 1.4 0.1 0.2 1.2 0.2 0.6 0.6 0.1 0.5 0.4 0.1 0.7 4.0 0.7 0.3 0.5 0.5 3.6 16.4 1.7 1.5 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.0 0.0 0.0 80.7 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.0 1.2 0.8 3.1 1.0 1.1 0.0 0.0 0.0 0.4 0.7 1.5 0.5 0.0 0.0 6.2 0.1 0.4 3.3 0.2 9.6 0.0 0.2 0.6 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 1.9 0.0 81.8 0.2 0.1 0.4 0.0 0.0 12.8 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 19.7 0.6 0.2 0.0 1.0 0.0 0.0 0.0 1.0 0.9 0.0 0.0 1.2 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.3 3.7 0.3 0.5 9.7 0.4 0.0 0.1 0.0 0.0 6.0 SNX8 Mvp1 ENSG00000106266 "Sorting nexin 8" Q9Y5X2 7 2251770-2354318 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 108.9;Late spermatids: 358.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 100.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057296, HPA060194" Approved Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA057296: AB_2683401, HPA060194: AB_2684219" "unprognostic (2.22e-2)" "unprognostic (3.38e-1)" "unprognostic (9.85e-3)" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (9.32e-2)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.23e-2)" "unprognostic (1.91e-3)" "unprognostic (1.54e-2)" "unprognostic (3.06e-1)" "unprognostic (6.01e-2)" "unprognostic (1.54e-1)" "unprognostic (5.10e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-2)" "unprognostic (1.35e-1)" 15.4 6.8 13.7 11.3 14.1 10.9 12.4 11.8 11.4 7.0 10.9 7.7 10.6 6.9 3.1 10.2 7.0 9.8 12.8 12.9 11.3 7.3 7.2 9.7 21.5 15.1 13.0 7.5 7.5 5.9 5.4 9.3 13.3 4.3 6.8 5.7 7.8 3.0 11.0 10.2 9.5 5.6 12.9 32.7 6.9 23.2 15.1 7.9 8.3 7.5 17.7 8.5 5.7 14.9 40.3 38.7 15.6 21.8 21.3 20.5 36.7 19.2 28.4 31.8 39.2 27.3 30.6 23.4 7.7 22.8 100.9 10.6 13.6 10.5 16.1 5.9 12.8 13.0 15.5 22.9 53.9 12.7 20.8 41.4 12.1 39.0 15.0 8.5 12.1 18.3 26.0 26.9 26.4 26.4 4.3 13.5 28.4 22.4 19.0 20.6 32.2 10.7 7.5 18.8 7.5 19.7 17.4 47.8 27.3 17.0 35.5 27.4 18.5 26.6 69.7 44.0 25.4 17.5 22.9 21.9 26.4 16.9 73.6 11.8 15.4 5.1 2.9 17.2 2.1 26.1 2.1 2.9 21.8 30.6 2.0 2.4 2.6 2.2 17.8 5.4 3.4 8.7 13.7 14.1 11.8 11.4 12.9 11.3 15.1 13.0 13.3 12.9 15.1 14.9 7.4 6.4 9.4 3.9 35.7 5.2 7.8 6.1 2.8 10.0 12.3 10.4 12.4 10.0 4.8 3.7 8.4 16.7 7.7 10.5 13.7 21.0 108.9 3.3 12.8 13.0 6.0 26.3 5.0 30.0 15.4 10.3 10.7 4.5 12.6 8.2 45.3 8.8 78.1 21.9 7.8 10.9 6.1 35.2 75.2 358.9 12.2 36.7 14.2 6.5 41.9 7.8 7.2 2.5 9.1 26.9 7.9 13.2 12.9 8.8 12.5 14.9 5.5 12.5 0.0 5.3 9.6 10.6 22.9 5.7 6.1 43.4 6.3 29.6 9.7 9.2 SOD3 EC-SOD ENSG00000109610 "Superoxide dismutase 3" P08294 4 24789912-24800842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Antioxidant, Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 436.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 498.5;Leydig cells: 424.1;Peritubular cells: 365.6;Smooth muscle cells: 428.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 66.2;BJ: 38.1;PC-3: 55.1;RPTEC TERT1: 231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042110 Supported "Secreted to blood" NA NA 50400000 510000000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "HPA042110: AB_2677850" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (8.80e-2)" "unprognostic (3.32e-2)" "unprognostic (9.66e-2)" "unprognostic (1.73e-1)" "unprognostic (4.98e-2)" "unprognostic (3.68e-1)" "unprognostic (2.39e-1)" "unprognostic (3.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.80e-2)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.45e-2)" 221.4 20.4 14.3 26.1 20.9 0.0 134.2 15.8 23.8 226.5 436.1 122.7 18.2 151.6 10.4 62.1 177.6 22.4 150.1 47.1 14.1 124.1 16.5 155.0 10.6 22.9 23.4 59.7 86.7 2.6 19.8 39.8 17.5 131.3 13.4 1.9 70.9 23.4 22.0 91.9 65.2 37.1 16.4 24.8 102.1 74.1 19.0 5.8 176.6 22.9 7.0 178.3 170.4 13.6 0.0 0.0 0.0 0.0 66.2 17.3 2.0 38.1 16.7 2.3 1.4 0.5 0.0 0.0 11.8 8.0 0.1 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.9 0.2 0.0 0.0 16.8 0.0 15.8 0.0 17.9 0.1 0.0 1.1 0.0 0.0 0.1 0.3 1.1 8.0 0.0 55.1 0.0 0.0 0.6 231.3 0.8 0.2 0.2 0.0 1.2 0.0 2.1 32.8 0.0 0.0 8.7 1.0 1.6 0.4 0.1 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 20.9 15.8 23.8 47.1 14.1 22.9 23.4 17.5 16.4 19.0 13.6 46.1 12.8 18.1 7.2 1.0 90.8 65.5 0.6 10.2 0.4 21.7 22.1 23.0 144.4 7.6 90.1 0.0 211.4 1.8 25.6 15.6 63.6 18.7 81.9 45.8 21.0 34.6 0.0 0.1 1.8 17.0 498.5 5.1 80.3 0.0 0.1 15.4 0.2 17.3 0.0 0.1 51.9 0.0 0.3 115.5 33.9 424.1 3.2 80.0 3.7 0.0 20.7 0.0 0.5 0.7 3.5 89.3 365.6 1.1 80.4 0.0 142.7 0.1 1.4 197.2 6.5 428.9 73.2 4.4 6.1 70.3 190.0 7.6 6.1 51.8 9.6 SOST "DAND6, VBCH" ENSG00000167941 Sclerostin Q9BQB4 17 43753738-43758791 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" Heparin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "kidney: 13.3" "Cell type enhanced" "Detected in some" "B-cells: 1.4;Collecting duct cells: 1.8" "Cancer enhanced" "Detected in some" "lung cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HaCaT: 5.2;SuSa: 3.0" "Group enriched" "Detected in some" 11 "basal ganglia: 1.7;cerebellum: 1.0" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA 16000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.26e-1)" "unprognostic (4.06e-2)" "unprognostic (6.57e-2)" "unprognostic (2.55e-3)" "unprognostic (3.37e-1)" "unprognostic (4.67e-2)" "unprognostic (1.16e-1)" "unprognostic (8.35e-2)" "unprognostic (1.38e-2)" "unprognostic (1.20e-1)" "unprognostic (8.92e-2)" "unprognostic (1.56e-1)" "unprognostic (7.90e-2)" 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 13.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 111.3;stomach 1: 60.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 68.5;Distal tubular cells: 29.4;Gastric mucus-secreting cells: 76.5;Horizontal cells: 30.3;Ionocytes: 128.1;Melanocytes: 32.0" "Cancer enhanced" "Detected in many" "renal cancer: 25.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;EFO-21: 12.7;HEL: 4.8;NTERA-2: 4.9;RPTEC TERT1: 23.5" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (2.08e-2)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.17e-3)" "unprognostic (5.59e-3)" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (1.41e-2)" "prognostic favorable (8.69e-4)" "unprognostic (2.59e-1)" "unprognostic (2.62e-1)" "prognostic favorable (3.22e-5)" "unprognostic (7.01e-2)" "unprognostic (1.23e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (8.72e-4)" 0.2 0.5 1.3 0.9 2.7 0.1 17.9 1.7 3.4 2.6 111.3 10.9 11.6 4.7 0.3 3.7 5.0 0.3 3.1 3.7 0.3 22.3 0.0 39.2 0.1 0.7 0.9 1.1 0.6 0.6 2.4 0.0 0.1 1.8 15.0 3.0 15.6 3.5 0.1 16.8 8.6 1.1 0.2 0.1 60.4 1.9 2.2 0.1 8.6 0.9 3.9 1.4 3.5 1.8 0.0 0.0 7.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 12.7 0.0 0.0 0.3 0.4 0.0 0.0 0.1 2.6 4.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.3 0.1 0.0 0.1 0.7 0.9 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.7 1.7 3.4 3.7 0.3 0.7 0.9 0.1 0.2 2.2 1.8 0.4 0.0 0.0 0.0 0.2 5.6 4.3 2.1 9.1 0.6 68.5 17.8 3.8 0.0 2.0 14.7 0.0 0.0 0.4 1.2 29.4 0.0 19.7 1.0 0.1 2.9 2.4 0.0 0.0 0.0 0.0 3.9 76.5 1.5 0.0 0.0 0.4 0.1 0.0 30.3 0.0 0.2 128.1 0.0 1.2 13.0 7.2 0.4 32.0 0.0 0.0 14.2 0.0 0.0 0.0 0.4 2.2 2.6 0.4 1.1 0.0 21.8 0.0 0.7 0.0 0.1 0.3 3.4 1.2 14.1 7.2 0.0 0.9 0.0 2.3 1.5 SOWAHA ANKRD43 ENSG00000198944 "Sosondowah ankyrin repeat domain family member A" Q2M3V2 5 132813302-132816786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 100.9;intestine: 39.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 39.5;Horizontal cells: 132.9;Muller glia cells: 26.8;Proximal enterocytes: 108.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "SCLC-21H: 13.4;T-47d: 32.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 61.0" HPA064621 Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "HPA064621: AB_2685302" "unprognostic (1.59e-1)" "unprognostic (5.58e-2)" "unprognostic (3.75e-3)" "unprognostic (5.34e-3)" "unprognostic (8.28e-2)" "unprognostic (3.05e-3)" "unprognostic (1.18e-1)" "unprognostic (5.99e-2)" "unprognostic (1.27e-1)" "unprognostic (2.65e-2)" "prognostic favorable (4.03e-4)" "unprognostic (3.92e-2)" "prognostic favorable (9.38e-5)" "unprognostic (4.36e-1)" "unprognostic (3.00e-1)" "unprognostic (2.53e-3)" "unprognostic (1.42e-1)" 0.4 0.8 62.6 0.6 100.9 0.0 0.5 13.2 59.2 0.3 5.3 8.3 36.4 0.0 6.1 0.1 1.4 1.6 0.1 49.7 13.3 4.8 1.8 0.1 0.0 12.9 13.0 0.2 2.4 1.2 2.6 0.1 15.3 2.6 6.7 4.3 3.2 2.8 0.0 0.2 39.3 0.0 15.0 0.0 5.6 0.5 24.3 2.0 1.1 0.0 0.1 1.1 0.1 23.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.9 1.5 0.0 0.7 0.0 0.1 0.0 2.6 0.4 0.1 0.0 2.9 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 1.0 1.7 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.7 13.4 0.5 0.1 0.0 0.0 1.6 32.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.6 100.9 13.2 59.2 49.7 13.3 12.9 13.0 15.3 15.0 24.3 23.5 0.0 0.0 0.0 1.6 0.2 0.0 0.4 0.1 0.0 0.7 1.0 0.1 0.3 14.3 0.2 5.5 0.0 0.4 0.0 39.5 0.0 0.3 0.0 0.5 0.1 0.1 11.5 0.0 4.8 1.1 0.0 0.1 2.6 0.5 0.0 0.0 0.0 2.1 0.1 132.9 0.6 19.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 26.8 0.0 5.5 15.2 0.4 21.0 0.4 0.0 2.2 108.7 5.5 0.8 3.1 0.0 0.0 0.0 0.9 0.9 0.0 0.0 0.1 0.2 0.0 19.1 0.6 SP2 KIAA0048 ENSG00000167182 "Sp2 transcription factor" Q02086 17 47896150-47928957 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003357, CAB010245" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm Vesicles "CAB010245: AB_2121523, HPA003357: AB_1080070" "unprognostic (1.23e-1)" "unprognostic (1.66e-2)" "unprognostic (6.30e-3)" "unprognostic (5.85e-2)" "unprognostic (1.18e-1)" "unprognostic (6.91e-2)" "unprognostic (5.66e-2)" "unprognostic (2.46e-1)" "unprognostic (6.46e-2)" "unprognostic (2.52e-1)" "unprognostic (1.44e-1)" "unprognostic (5.39e-2)" "prognostic favorable (1.82e-5)" "unprognostic (5.34e-3)" "unprognostic (4.28e-2)" "unprognostic (3.37e-2)" "unprognostic (8.66e-2)" 14.8 10.7 9.4 16.6 11.6 19.4 15.4 16.1 11.5 12.9 6.9 14.3 14.9 14.7 12.0 17.2 15.1 11.5 18.3 9.6 10.1 12.5 8.7 14.9 20.6 12.4 10.4 15.1 16.0 23.5 9.8 13.6 11.1 13.5 13.3 10.5 16.2 12.5 32.2 14.8 15.6 12.8 8.3 17.7 13.0 17.8 11.8 25.3 18.1 26.6 15.0 13.6 13.4 13.3 33.5 37.3 25.1 21.6 12.1 11.2 26.1 19.3 13.6 19.0 17.1 41.3 16.2 28.6 17.4 24.7 20.1 25.6 17.5 16.4 19.9 41.7 26.6 28.5 25.6 22.3 11.2 26.4 34.2 16.4 19.1 22.4 21.1 13.5 18.5 26.3 31.8 47.5 18.8 45.0 64.6 16.8 11.8 29.6 24.9 30.8 34.4 18.6 13.4 52.1 26.8 31.4 16.9 17.9 20.0 15.0 26.7 25.6 30.3 34.8 18.1 24.2 30.1 42.3 50.6 26.0 19.0 18.5 29.2 13.6 6.1 9.9 8.3 7.0 7.3 4.9 6.3 7.9 4.9 5.6 7.1 7.4 11.3 9.7 6.6 4.5 7.2 6.6 9.4 11.6 16.1 11.5 9.6 10.1 12.4 10.4 11.1 8.3 11.8 13.3 14.6 9.6 19.5 5.2 17.7 6.2 15.8 7.8 12.0 9.0 9.8 9.9 9.7 12.8 8.3 11.0 0.0 10.7 11.3 16.4 15.6 7.0 9.8 8.1 6.2 11.6 15.6 25.2 5.2 7.6 9.2 9.4 8.6 10.7 13.3 5.5 8.2 7.5 8.9 11.8 4.8 9.0 14.2 10.9 8.2 10.5 10.5 14.2 8.8 6.5 11.7 12.1 17.5 9.0 9.9 7.3 13.2 3.4 12.7 11.0 8.6 8.1 10.2 6.5 6.6 12.6 12.5 9.8 6.3 9.6 7.5 20.5 14.8 5.3 7.9 17.0 SP4 "HF1B, MGC130008, MGC130009, SPR-1" ENSG00000105866 "Sp4 transcription factor" Q02446 7 21428043-21514822 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 50.3;Oligodendrocytes: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010246, HPA040395" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "CAB010246: AB_2194481, HPA040395: AB_2676959" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" "unprognostic (6.04e-2)" "unprognostic (8.28e-2)" "unprognostic (9.14e-2)" "unprognostic (8.51e-2)" "unprognostic (1.09e-2)" "unprognostic (7.85e-2)" "unprognostic (1.15e-1)" "unprognostic (4.06e-1)" "unprognostic (3.15e-3)" "unprognostic (1.89e-1)" "unprognostic (6.04e-3)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "unprognostic (6.18e-2)" "unprognostic (7.80e-3)" 1.9 2.5 2.1 4.5 3.2 6.8 3.6 10.0 2.5 3.7 1.4 2.0 1.7 5.5 3.0 2.2 4.3 2.5 3.8 1.7 2.8 2.9 2.1 3.5 6.5 2.4 1.8 11.3 2.3 7.2 2.5 2.0 1.9 4.0 2.4 8.9 2.2 2.7 3.6 1.9 2.4 2.9 2.1 5.9 2.9 3.8 2.7 13.5 7.8 7.6 6.8 2.9 1.7 4.4 3.6 2.2 6.7 10.6 2.1 1.4 2.0 3.4 2.2 3.6 4.7 5.5 3.5 14.1 2.3 2.0 9.6 4.2 10.0 2.9 6.9 4.6 4.5 6.5 4.6 2.1 1.5 5.4 7.7 1.4 2.4 3.8 4.3 1.8 7.1 9.6 9.5 9.2 2.9 1.3 13.8 3.7 17.5 6.4 2.7 33.1 11.6 4.6 1.2 2.2 8.8 11.0 7.1 3.0 2.5 6.6 3.6 4.0 3.2 5.7 8.3 3.5 6.5 14.0 15.0 21.0 3.4 8.7 8.1 5.7 0.8 8.9 6.9 1.0 8.2 3.7 6.4 6.6 1.0 5.9 8.2 6.9 2.1 3.9 2.1 1.8 8.4 3.8 2.1 3.2 10.0 2.5 1.7 2.8 2.4 1.8 1.9 2.1 2.7 4.4 11.0 3.2 9.0 19.6 21.8 12.6 11.6 2.5 14.2 17.5 10.0 7.5 9.7 8.6 5.7 0.0 8.4 0.9 13.1 1.6 0.0 2.2 7.0 5.4 7.0 7.8 10.7 21.9 31.0 2.2 1.3 6.3 5.6 7.9 5.1 10.8 10.8 4.6 1.8 18.5 31.3 2.2 2.0 6.0 6.4 4.8 5.6 6.0 7.2 27.2 4.5 10.3 18.6 50.3 60.2 1.7 12.3 6.8 7.1 7.7 1.2 2.0 1.6 21.0 0.0 17.3 6.9 7.3 8.4 4.8 11.1 1.5 22.2 2.8 3.1 5.3 SPAAR "LINC00961, SPAR" ENSG00000235387 "Small regulatory polypeptide of amino acid response" A0A1B0GVQ0 9 35909490-35937153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.4;breast: 10.8" "Cell type enriched" "Detected in some" 7 "Adipocytes: 42.3" "Cancer enhanced" "Detected in many" "renal cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HUVEC TERT2: 34.0;TIME: 40.1" "Not detected" "Not detected" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.17e-1)" "unprognostic (2.19e-2)" "unprognostic (1.91e-2)" "unprognostic (7.00e-3)" "unprognostic (4.23e-2)" "unprognostic (2.61e-3)" "unprognostic (6.95e-2)" "unprognostic (1.00e-1)" "unprognostic (3.40e-3)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (7.72e-2)" "unprognostic (7.12e-3)" "unprognostic (1.67e-2)" "unprognostic (3.04e-1)" "unprognostic (1.27e-1)" "unprognostic (3.22e-1)" 12.4 1.2 2.9 0.6 2.5 0.0 10.8 2.2 3.3 0.7 1.1 1.2 0.3 1.2 0.1 0.5 1.2 0.6 8.9 2.3 2.2 4.2 0.8 3.2 0.4 3.0 2.6 0.7 0.5 0.5 0.6 4.7 3.1 1.0 0.4 1.4 0.7 0.5 3.1 0.9 0.9 0.6 2.3 0.7 0.9 7.5 3.3 0.2 1.9 1.8 0.0 1.5 0.8 2.4 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.6 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.4 0.1 0.2 0.0 0.0 34.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 40.1 0.0 0.8 2.7 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.5 2.2 3.3 2.3 2.2 3.0 2.6 3.1 2.3 3.3 2.4 42.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 5.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 SPACA3 "ALLP17, CT54, LYC3, LYZL3, SLLP1" ENSG00000141316 "Sperm acrosome associated 3" Q8IXA5 17 32970376-32997877 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 125.3" "Group enriched" "Detected in some" 75 "Early spermatids: 1298.4;Late spermatids: 933.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 5 "B-cells: 1.2" "Cell line enriched" "Detected in some" 16 "U-266/70: 91.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA023633 Enhanced "Secreted in male reproductive system" NA NA "Cluster 37: B-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA023633: AB_1857407" "unprognostic (6.48e-2)" "unprognostic (2.83e-1)" "unprognostic (1.30e-1)" "unprognostic (7.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.31e-2)" "unprognostic (3.37e-1)" "unprognostic (5.91e-2)" "unprognostic (1.68e-1)" "unprognostic (5.70e-4)" "unprognostic (3.86e-2)" "unprognostic (1.79e-1)" "unprognostic (4.63e-1)" 0.1 0.0 0.2 0.1 0.0 0.3 0.1 0.7 0.3 0.0 0.1 0.1 0.0 0.1 0.2 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 20.9 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.2 125.3 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 91.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.7 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1298.4 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 1.6 0.0 0.0 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 933.6 13.1 1.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 4.9 0.4 0.0 3.8 0.0 0.7 0.0 6.6 0.0 0.0 14.7 6.9 0.0 0.0 0.0 0.0 0.1 0.9 0.0 SPACA4 SAMP14 ENSG00000177202 "Sperm acrosome associated 4" Q8TDM5 19 48606742-48607714 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 117.8" "Cell type enriched" "Detected in some" 5 "Early spermatids: 1014.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041927, HPA061302" Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA041927: AB_10794162, HPA061302: AB_2684475" "unprognostic (2.48e-2)" "unprognostic (6.37e-4)" "unprognostic (6.59e-2)" "unprognostic (4.52e-2)" "unprognostic (2.09e-3)" "unprognostic (9.43e-6)" "unprognostic (6.67e-3)" "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (2.78e-1)" "unprognostic (3.43e-1)" "unprognostic (2.88e-1)" "unprognostic (4.47e-1)" "unprognostic (2.01e-2)" 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.3 0.6 0.0 3.6 3.0 0.0 0.0 2.0 0.2 1.1 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.9 0.0 0.1 1.4 3.1 0.0 0.0 0.0 3.4 117.8 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.2 0.6 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1014.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 185.9 4.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 9.8 3.3 0.0 1.6 0.0 0.0 0.0 0.0 0.2 SPACA5 "dJ54B20.3, LYC5, LYZL5, PNPK6288, SLLP2, UNQ6288" ENSG00000171489 "Sperm acrosome associated 5" Q96QH8 X 48004336-48009729 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 14.0" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Early spermatids: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA044747: AB_2679071, HPA047149: AB_2679955" 0.0 0.0 0.6 0.0 0.7 0.1 0.1 1.2 0.9 0.1 0.2 0.1 0.0 0.2 0.5 0.0 0.2 0.1 0.0 0.3 0.6 0.1 0.0 0.1 0.4 0.7 0.7 0.2 0.9 0.0 0.0 0.0 0.7 0.2 0.1 0.3 0.1 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.1 14.0 0.8 0.0 0.8 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.6 0.7 1.2 0.9 0.3 0.6 0.7 0.7 0.7 0.2 0.8 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPACA5B LYZL5B ENSG00000171478 "Sperm acrosome associated 5B" Q96QH8 X 48130657-48132613 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 54 "testis: 23.9" "Cell type enriched" "Detected in single" 16 "Early spermatids: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA044747: AB_2679071, HPA047149: AB_2679955" 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.2 0.4 0.2 0.4 0.2 0.3 0.3 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPACA7 C13orf28 ENSG00000153498 "Sperm acrosome associated 7" Q96KW9 13 112376355-112434689 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 109 "testis: 84.1" "Group enriched" "Detected in some" 22 "Early spermatids: 1259.3;Late spermatids: 829.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA048349 Enhanced "Secreted in male reproductive system" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA048349: AB_2732548" "unprognostic (3.97e-2)" 0.0 0.1 0.1 0.1 0.4 0.5 0.0 0.7 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.2 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 84.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.7 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.7 0.4 0.2 0.2 0.3 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1259.3 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 829.7 6.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.7 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPAG11A "EDDM2A, HE2" ENSG00000178287 "Sperm associated antigen 11A" Q6PDA7 8 7847876-7868867 "Predicted intracellular proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11461 "epididymis: 4564.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.3;NB-4: 5.7;RPMI-8226: 1.7" "HPA023842, HPA057479" Supported Approved "Golgi apparatus" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA023842: AB_2732429, HPA057479: " 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4564.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPAG11B "EDDM2B, EP2, EP2C, EP2D, HE2" ENSG00000164871 "Sperm associated antigen 11B" Q08648 8 7442684-7463674 "Predicted intracellular proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1636 "epididymis: 864.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023842, HPA057479" Supported Approved "Golgi apparatus" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA023842: AB_2732429, HPA057479: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 864.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 SPAG9 "CT89, FLJ13450, FLJ14006, FLJ26141, FLJ34602, HLC4, HSS, JIP-4, JIP4, JLP, KIAA0516, MGC117291, MGC14967, MGC74461, PHET, PIG6, SYD1" ENSG00000008294 "Sperm associated antigen 9" O60271 17 50962174-51120868 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 9.2;neutrophil: 12.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 12.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040446, HPA061458" Enhanced Enhanced "Centriolar satellite,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 44: Endometrium - Transcription" "Centriolar satellite, Cytosol" "HPA040446: AB_10671691, HPA061458: AB_2684528" "unprognostic (1.36e-1)" "unprognostic (6.61e-2)" "unprognostic (6.04e-3)" "unprognostic (4.65e-2)" "unprognostic (3.52e-2)" "unprognostic (9.73e-2)" "unprognostic (8.13e-2)" "unprognostic (3.72e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (2.83e-2)" "unprognostic (9.71e-2)" "unprognostic (2.23e-3)" "unprognostic (2.27e-2)" "unprognostic (9.53e-2)" "unprognostic (7.67e-2)" "prognostic unfavorable (8.10e-4)" 32.2 22.6 50.9 19.0 64.6 26.7 22.4 60.7 58.4 21.5 38.2 23.1 20.4 27.6 12.3 29.1 18.7 26.7 22.6 44.2 55.1 33.0 32.9 30.4 13.6 64.0 56.0 30.1 30.6 27.4 17.5 32.0 65.1 17.9 19.7 36.6 14.3 19.3 66.3 22.6 21.0 27.0 58.7 18.4 15.9 51.0 60.1 19.3 40.1 40.6 15.7 29.6 20.0 99.1 53.3 58.5 73.3 36.0 68.0 59.9 64.7 42.6 41.5 46.8 57.9 53.0 35.7 28.6 29.1 70.3 94.1 44.7 48.5 35.8 86.4 43.5 57.7 23.9 46.4 39.5 51.1 34.9 26.8 43.4 40.7 63.3 112.4 44.9 38.9 14.2 53.6 30.9 66.9 26.6 22.0 14.5 19.5 35.5 74.8 24.7 81.8 25.3 42.8 99.4 56.6 78.8 37.6 34.5 38.8 44.0 28.5 40.9 54.6 129.6 30.3 101.0 63.4 43.5 67.4 46.2 44.3 20.4 46.0 9.2 1.2 0.7 1.2 0.8 0.9 1.0 1.0 1.2 1.3 0.9 0.6 0.8 12.1 0.4 0.5 1.0 1.7 0.5 50.9 64.6 60.7 58.4 44.2 55.1 64.0 56.0 65.1 58.7 60.1 99.1 162.5 131.4 121.3 190.3 53.1 165.1 149.7 37.5 107.6 96.0 45.7 38.7 62.6 41.5 41.1 25.8 125.1 43.2 60.2 189.0 27.4 56.7 243.0 151.6 142.1 122.9 69.8 20.4 110.2 57.6 28.4 106.5 81.6 337.1 43.1 52.8 74.3 48.7 36.7 67.3 130.5 56.0 24.4 43.3 246.6 137.8 76.1 123.1 71.2 104.9 49.8 32.7 25.7 192.5 304.7 89.6 123.5 67.0 59.7 156.9 69.6 86.9 39.0 85.5 65.7 109.0 86.4 215.1 54.8 93.8 172.3 138.9 59.4 56.3 56.3 182.5 SPAM1 "HYAL5, PH-20, SPAG15" ENSG00000106304 "Sperm adhesion molecule 1" P38567 7 123925237-123971414 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 17.3" "Group enriched" "Detected in some" 73 "Early spermatids: 270.3;Late spermatids: 111.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA017984 Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA017984: AB_1857413" "unprognostic (2.44e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 270.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 111.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 737.1;Endometrial stromal cells: 1209.0;Endothelial cells: 781.9;Fibroblasts: 1032.1;Peritubular cells: 1111.1;Sertoli cells: 2353.5;Smooth muscle cells: 1527.3;Theca cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cell line enhanced" "Detected in many" "ASC diff: 4911.5;BJ: 4101.8;fHDF/TERT166: 6492.5;WM-115: 4789.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" 1661.2 406.4 578.0 436.4 922.0 32.4 528.6 733.1 339.2 837.2 297.8 355.6 110.5 538.9 112.7 307.7 271.4 1526.8 563.5 362.9 1554.2 176.1 158.5 498.0 232.1 1370.4 1251.5 348.2 119.2 273.1 111.4 2184.6 1224.8 227.1 185.2 36.4 113.1 378.0 258.2 286.1 157.4 1251.5 995.9 260.8 143.3 406.7 1135.4 70.9 294.1 473.5 131.6 829.5 249.0 1088.4 5.9 5.0 1196.5 57.5 4911.5 1596.0 112.6 4101.8 1336.6 1649.3 1693.8 5.5 4.2 2.0 953.7 6492.5 272.0 56.7 153.4 316.2 555.0 4.8 57.1 56.7 0.4 116.8 1441.6 2.9 5.4 2567.2 436.9 1233.8 170.8 1903.1 2315.1 13.5 53.7 44.6 944.1 0.4 4.7 35.5 556.2 0.4 4.4 2.9 1192.9 4.3 0.5 0.5 45.5 88.4 2.8 1.4 534.9 1922.1 4.7 138.2 2759.9 771.0 1195.2 350.2 1304.4 3.7 6.0 7.6 648.4 3.7 4789.0 10.4 8.7 2.7 1.0 0.3 0.0 0.1 0.0 0.1 2.3 0.2 0.3 0.0 24.3 0.0 0.1 1.9 0.0 123.9 578.0 922.0 733.1 339.2 362.9 1554.2 1370.4 1251.5 1224.8 995.9 1135.4 1088.4 737.1 83.3 27.5 7.2 6.8 164.8 25.7 23.8 28.5 85.7 11.2 100.5 43.6 5.7 18.8 16.5 2.1 115.4 2.8 0.1 0.0 4.6 14.2 41.6 1209.0 781.9 0.0 15.1 4.3 0.4 354.3 1032.1 9.7 31.5 12.0 146.5 668.6 9.9 108.2 1.7 2.9 0.0 0.0 50.0 175.7 46.8 319.3 92.0 234.7 38.4 10.7 13.6 3.1 21.6 37.3 5.5 0.0 1111.1 4.1 7.7 0.0 42.0 7.8 72.7 2353.5 510.4 1527.3 14.2 10.9 4.8 108.3 147.4 21.1 987.4 0.0 5.3 SPARCL1 MAST9 ENSG00000152583 "SPARC like 1" Q14515 4 87473335-87531061 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 4430.9;Endothelial cells: 2372.1;Peritubular cells: 2523.5;Sertoli cells: 4674.1;Skeletal myocytes: 2379.0;Smooth muscle cells: 2781.9" "Cancer enhanced" "Detected in all" "glioma: 528.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 24.9;SuSa: 31.4;U-266/70: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026225 Enhanced "Secreted in other tissues" NA NA 630000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB026225: " "unprognostic (1.02e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.63e-3)" "unprognostic (1.73e-2)" "unprognostic (3.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (2.45e-3)" "unprognostic (1.76e-2)" "unprognostic (5.72e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (3.33e-4)" 755.6 129.5 664.6 124.5 810.9 0.5 532.1 612.4 1058.4 732.7 580.4 624.3 125.1 1244.5 443.8 308.1 754.5 487.9 600.2 744.6 723.5 72.5 25.0 481.1 99.1 655.7 730.9 286.8 91.8 128.0 197.8 315.4 663.4 584.2 187.5 95.2 228.3 999.2 244.8 130.2 280.1 1191.2 774.7 157.9 347.7 97.5 694.8 103.2 369.9 594.7 100.0 488.0 466.4 681.2 0.7 0.0 24.9 0.3 0.2 0.1 2.6 0.1 0.1 0.0 0.0 0.0 0.1 0.4 1.8 0.0 0.0 1.4 2.4 0.0 0.0 1.7 0.0 0.3 1.1 0.4 1.1 0.3 1.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.3 0.0 0.5 0.2 3.5 0.6 0.0 0.0 0.3 0.4 1.2 0.0 0.1 0.8 1.6 0.1 0.2 0.1 31.4 0.4 0.5 0.0 0.2 0.3 1.5 0.2 9.1 1.4 0.6 3.4 0.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 664.6 810.9 612.4 1058.4 744.6 723.5 655.7 730.9 663.4 774.7 694.8 681.2 4430.9 12.8 56.4 1155.7 6.2 46.3 187.2 0.6 59.7 10.7 24.4 251.6 334.2 4.3 43.3 7.3 2.1 2.2 8.6 0.0 13.7 0.8 11.8 34.9 935.8 2372.1 0.0 32.0 382.3 0.4 3.2 1413.1 6.1 46.7 7.6 1.4 899.5 9.1 9.2 3.3 450.1 0.0 0.0 5.3 55.2 47.0 659.5 31.6 56.9 261.4 0.0 179.4 0.0 210.6 53.8 0.1 0.0 2523.5 25.2 50.4 0.0 24.6 7.4 34.4 4674.1 2379.0 2781.9 5.7 7.9 56.8 39.9 2.5 26.9 38.8 0.0 124.2 SPATA20 "FLJ21347, SSP411, Tisp78" ENSG00000006282 "Spermatogenesis associated 20" Q8TB22 17 50543058-50555852 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 117.5" "Group enriched" "Detected in all" 15 "Early spermatids: 594.1;Late spermatids: 1543.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 60.1;MCF7: 59.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA022023, HPA027144, HPA031442" Enhanced Approved Nucleoplasm "Secreted in male reproductive system" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA022023: AB_1857417, HPA027144: AB_1857418, HPA031442: AB_10610557" "unprognostic (9.27e-3)" "unprognostic (1.90e-1)" "unprognostic (9.60e-2)" "unprognostic (9.74e-3)" "unprognostic (2.63e-3)" "unprognostic (7.23e-2)" "unprognostic (1.56e-1)" "unprognostic (3.07e-1)" "unprognostic (7.09e-2)" "unprognostic (8.71e-2)" "unprognostic (6.12e-3)" "unprognostic (4.93e-2)" "unprognostic (6.74e-2)" "unprognostic (1.75e-1)" "unprognostic (2.29e-1)" "unprognostic (2.66e-1)" "prognostic favorable (9.69e-5)" 10.3 36.8 25.7 7.2 24.6 4.4 10.5 25.5 33.2 16.9 30.0 14.8 10.0 18.0 9.7 10.1 13.7 12.9 33.3 24.2 27.6 18.6 17.6 8.9 6.4 26.9 28.0 21.1 22.0 17.0 11.7 6.4 27.5 17.1 6.4 3.2 17.7 11.2 18.5 8.6 10.8 8.3 26.0 14.1 22.0 117.5 33.1 2.3 22.5 18.4 3.8 14.6 10.3 24.8 8.8 39.4 4.8 25.7 7.9 22.7 6.0 14.9 24.2 9.2 7.3 29.1 12.9 9.2 38.4 13.9 8.9 7.0 1.4 6.3 4.2 14.4 5.3 7.4 9.5 60.1 27.8 2.4 17.1 33.3 8.8 4.7 13.0 17.9 11.6 2.4 0.7 16.8 5.5 59.3 0.0 2.1 3.1 19.0 18.0 4.4 6.9 2.9 35.4 39.5 4.5 11.3 13.0 12.1 17.0 5.6 21.0 1.1 19.7 9.8 22.2 5.6 3.7 31.8 14.0 0.2 14.9 1.4 6.9 0.0 5.0 1.0 1.6 4.5 1.9 2.8 1.2 1.1 8.3 1.7 1.5 1.7 0.2 7.3 3.4 1.6 0.8 3.7 25.7 24.6 25.5 33.2 24.2 27.6 26.9 28.0 27.5 26.0 33.1 24.8 12.6 6.4 5.0 17.3 14.0 10.7 15.1 13.4 25.6 5.3 13.3 17.4 32.5 20.0 13.1 23.9 4.2 17.3 9.8 32.6 27.4 35.6 594.1 13.0 13.2 11.7 37.9 6.1 10.3 39.0 10.3 23.5 66.8 23.2 17.7 38.5 10.8 26.7 34.6 11.8 9.5 28.4 16.2 23.6 14.8 1543.1 38.2 20.0 21.4 6.5 19.3 26.9 12.3 8.5 2.3 23.7 31.1 38.0 17.9 12.2 18.4 38.8 5.9 2.4 6.6 18.1 19.1 10.0 13.8 11.9 8.8 9.9 11.2 39.9 23.8 17.1 SPATA25 "C20orf165, dJ337O18.8, TSG23" ENSG00000149634 "Spermatogenesis associated 25" Q9BR10 20 45886489-45887635 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 24.0" "Cell type enriched" "Detected in some" 5 "Early spermatids: 304.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 6.7;HeLa: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA041386 Approved "Golgi apparatus" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus" "HPA041386: AB_2677446" "unprognostic (1.88e-1)" "unprognostic (2.66e-1)" "unprognostic (1.60e-1)" "unprognostic (4.92e-3)" "unprognostic (2.36e-1)" "unprognostic (1.84e-2)" "unprognostic (2.75e-3)" "unprognostic (1.57e-2)" "unprognostic (2.57e-2)" "unprognostic (3.45e-1)" "unprognostic (1.92e-3)" "unprognostic (1.67e-2)" "unprognostic (3.14e-1)" "unprognostic (5.07e-2)" "unprognostic (2.62e-1)" "unprognostic (5.93e-5)" "unprognostic (1.12e-1)" 3.0 1.8 1.9 1.8 3.2 0.6 1.6 4.2 2.4 2.4 3.3 2.6 4.5 3.2 2.3 2.2 2.8 2.1 3.2 1.7 1.7 5.5 5.2 1.1 1.5 2.3 2.2 6.5 2.3 2.5 1.6 1.7 1.9 2.1 2.2 4.3 2.5 3.1 9.9 2.6 3.3 3.6 1.5 1.8 1.6 24.0 2.5 6.8 2.9 3.4 1.1 3.1 2.1 2.8 0.6 2.1 1.5 1.7 2.3 1.4 1.7 0.4 1.8 0.9 0.3 6.7 3.7 1.2 0.5 0.8 1.9 2.8 0.8 0.5 0.3 0.4 1.4 0.6 6.2 4.4 1.7 0.1 1.0 3.2 1.0 0.4 0.5 2.4 0.6 2.0 0.9 1.6 0.7 1.4 0.8 0.0 0.9 0.6 1.1 1.6 1.0 0.8 0.1 0.9 2.9 1.6 1.9 1.3 1.9 0.6 2.2 1.6 0.5 1.1 1.2 0.8 0.6 1.4 0.9 0.3 1.5 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 3.2 4.2 2.4 1.7 1.7 2.3 2.2 1.9 1.5 2.5 2.8 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 304.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 58.3 2.1 0.1 0.0 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 1.1 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.0 SPCS3 "FLJ22649, PRO3567, SPC22/23, SPC3, YLR066W" ENSG00000129128 "Signal peptidase complex subunit 3" P61009 4 176319966-176332245 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 670.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 374.4" "Low region specificity" "Detected in all" HPA053180 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA053180: AB_2682071" "unprognostic (4.30e-2)" "unprognostic (1.38e-1)" "unprognostic (5.20e-3)" "prognostic favorable (8.89e-6)" "unprognostic (1.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.50e-3)" "unprognostic (1.79e-2)" "unprognostic (4.78e-3)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.87e-4)" "unprognostic (2.58e-2)" "unprognostic (2.85e-1)" "unprognostic (2.26e-1)" "unprognostic (4.92e-2)" "unprognostic (2.16e-2)" "unprognostic (1.44e-1)" 33.0 24.6 13.9 50.6 16.0 68.1 36.0 15.5 18.0 46.6 15.1 37.0 34.5 38.5 47.5 25.0 25.5 32.0 37.6 17.3 17.1 34.1 43.6 36.1 50.3 15.9 25.6 21.6 72.8 31.3 30.1 45.5 16.1 32.9 37.5 13.5 99.1 30.0 24.1 26.9 36.9 34.8 18.1 46.5 48.9 10.7 16.3 34.8 62.2 26.4 48.2 41.1 25.6 21.2 64.9 21.5 57.8 47.8 80.9 142.5 61.0 125.2 119.1 71.4 61.4 23.5 139.1 124.2 25.1 72.7 37.6 43.6 55.3 92.1 108.0 84.2 24.3 107.6 32.2 53.5 82.5 162.3 90.9 86.9 99.4 63.4 60.9 79.8 107.1 59.4 70.2 374.4 99.4 39.7 100.1 61.4 39.5 45.6 21.0 48.7 89.8 109.3 87.7 46.5 46.1 42.2 130.6 96.4 58.8 49.8 31.1 75.1 100.2 52.5 52.8 47.4 58.2 172.3 54.7 153.8 112.0 80.6 74.1 43.0 16.1 14.2 15.2 19.3 20.2 10.0 14.0 13.9 12.2 6.8 11.6 14.5 16.2 16.6 16.1 22.6 11.9 19.2 13.9 16.0 15.5 18.0 17.3 17.1 15.9 25.6 16.1 18.1 16.3 21.2 121.4 54.5 86.3 19.2 150.0 57.2 67.4 111.8 25.0 31.3 62.9 52.1 79.5 32.9 84.1 29.5 27.1 64.1 170.0 55.2 21.5 76.4 66.8 49.3 130.6 109.3 44.9 61.4 40.9 136.1 205.1 66.2 70.3 102.2 91.2 36.3 88.9 123.8 153.2 23.5 37.3 102.1 89.5 100.8 98.4 14.4 22.4 127.9 110.3 29.0 105.8 31.2 74.2 41.2 59.1 157.0 36.0 17.0 670.6 173.8 48.1 71.6 54.5 31.0 13.1 46.4 64.8 95.4 56.4 58.7 65.1 184.4 107.0 51.8 53.3 147.1 SPESP1 SP-ESP ENSG00000258484 "Sperm equatorial segment protein 1" Q6UW49 15 68818221-68946811 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 73.2" "Group enriched" "Detected in many" 4 "Early spermatids: 400.4;Spermatocytes: 455.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 17.8;BJ hTERT+ SV40 Large T+ RasG12V: 18.6;HBF TERT88: 21.7;HMC-1: 13.4;OE19: 15.9;RPTEC TERT1: 26.8;SCLC-21H: 19.9;WM-115: 31.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045936, HPA051040" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted in male reproductive system" NA NA 52000 "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA045936: AB_2679504, HPA051040: AB_2681322" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (9.82e-2)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (1.06e-1)" "unprognostic (5.96e-2)" "unprognostic (2.79e-1)" "unprognostic (2.40e-1)" "unprognostic (8.99e-2)" "unprognostic (1.10e-2)" "unprognostic (1.16e-2)" "unprognostic (2.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (9.67e-2)" 2.3 3.4 1.1 0.8 1.1 0.4 2.2 1.2 1.6 1.2 1.0 1.6 1.2 1.5 6.3 2.6 1.8 3.5 3.1 1.1 1.2 2.0 1.2 1.1 0.8 1.3 1.2 3.4 1.9 4.7 1.2 12.9 1.3 3.5 1.1 2.8 1.8 2.9 1.6 1.0 0.9 1.2 1.3 1.3 1.5 73.2 1.1 0.9 1.9 1.9 0.7 2.4 0.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 17.8 18.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 21.7 5.0 0.0 0.0 0.0 0.0 6.3 0.0 13.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 2.9 0.0 0.0 3.3 15.9 0.0 0.0 1.4 0.0 26.8 0.2 19.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 31.6 1.1 1.3 0.4 0.2 1.1 0.5 0.5 0.4 0.3 0.8 0.3 0.3 0.5 0.5 0.2 0.8 0.4 0.4 0.5 1.1 1.1 1.2 1.6 1.1 1.2 1.3 1.2 1.3 1.3 1.1 1.6 5.1 0.0 0.0 0.0 0.2 1.9 3.0 23.7 1.8 1.0 2.7 4.1 4.1 1.5 4.0 7.3 4.2 92.3 0.3 0.2 1.9 2.1 400.4 3.9 3.4 3.6 1.8 0.8 0.0 2.7 7.2 5.5 0.0 2.0 0.0 1.7 2.2 1.8 7.8 0.0 0.0 0.9 6.1 2.1 3.3 90.3 21.1 1.2 5.4 0.0 1.0 5.3 0.0 0.0 0.0 0.9 0.0 8.6 0.0 3.3 0.0 3.9 6.3 5.6 46.0 3.4 4.2 455.0 88.7 1.1 2.3 62.1 0.5 11.1 0.2 1.5 SPG7 "CAR, CMAR, SPG5C" ENSG00000197912 "SPG7 matrix AAA peptidase subunit, paraplegin" Q9UQ90 16 89490719-89557766 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "unprognostic (1.42e-1)" "unprognostic (1.72e-1)" "unprognostic (4.12e-2)" "prognostic favorable (2.22e-4)" "unprognostic (4.10e-1)" "unprognostic (1.11e-2)" "unprognostic (1.14e-1)" "unprognostic (1.50e-1)" "unprognostic (1.54e-1)" "unprognostic (2.33e-1)" "prognostic favorable (4.91e-4)" "unprognostic (3.56e-2)" "unprognostic (7.01e-2)" "unprognostic (1.44e-2)" "unprognostic (2.58e-1)" "unprognostic (1.71e-1)" "prognostic favorable (4.25e-4)" 29.8 44.8 19.3 7.0 18.8 8.2 27.9 21.3 28.6 31.5 18.5 33.3 9.9 31.8 4.0 28.2 26.4 6.8 52.3 19.4 18.3 32.4 47.0 24.9 8.9 19.7 18.6 39.0 31.9 13.8 38.7 5.9 20.3 31.2 8.1 9.9 29.0 9.7 56.7 31.3 35.5 9.0 16.9 34.1 31.1 31.9 18.7 10.5 53.1 31.0 8.0 30.1 26.9 20.0 11.5 28.3 17.3 26.6 33.2 24.2 10.9 27.3 24.6 21.0 10.4 23.0 22.3 16.5 32.5 20.1 16.2 30.5 21.5 24.4 14.7 11.7 25.3 11.4 12.0 43.4 16.2 5.5 10.3 15.2 20.1 12.8 14.1 27.9 25.6 22.0 23.1 5.5 21.7 21.0 14.4 22.5 21.9 23.8 21.4 31.8 26.2 10.8 15.9 17.3 16.4 10.5 44.9 8.3 9.5 15.2 22.6 17.0 33.7 13.9 17.2 12.0 12.2 13.7 19.8 12.8 17.7 19.8 17.7 4.5 2.5 3.9 2.7 2.4 2.6 1.6 1.7 1.3 2.8 3.4 3.1 2.0 2.9 3.7 1.7 2.3 1.8 1.0 19.3 18.8 21.3 28.6 19.4 18.3 19.7 18.6 20.3 16.9 18.7 20.0 53.9 48.1 49.4 39.2 45.6 15.9 27.9 30.1 44.9 57.8 31.2 37.2 45.8 22.8 41.5 35.0 95.9 39.9 47.6 42.3 19.6 40.0 66.0 50.5 41.7 49.9 37.2 27.3 58.5 25.8 28.8 35.9 67.2 54.1 21.5 95.3 51.0 38.1 32.2 40.4 53.1 43.8 30.5 34.8 21.8 22.1 42.9 35.2 21.4 35.6 42.6 30.5 51.5 87.0 46.2 39.5 39.5 33.4 43.5 29.5 68.2 23.8 37.7 73.7 6.6 36.9 36.2 57.5 36.5 36.7 18.0 25.9 45.5 68.3 51.0 28.7 SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 105.4;Muller glia cells: 165.1;Pancreatic endocrine cells: 101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 127.6;TIME: 108.9;U-251 MG: 142.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "olfactory bulb: 5.7" "HPA022829, HPA028761" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA022829: AB_1857438, HPA028761: AB_10600814" "unprognostic (1.04e-1)" "unprognostic (6.30e-2)" "unprognostic (1.09e-2)" "unprognostic (8.66e-2)" "unprognostic (2.25e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (9.32e-3)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (8.99e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.14e-6)" "unprognostic (1.39e-1)" "unprognostic (4.82e-2)" "unprognostic (8.29e-2)" "unprognostic (1.10e-3)" 18.9 4.1 4.0 10.5 3.0 17.3 18.0 2.1 3.9 11.0 2.3 7.0 1.9 6.7 3.9 23.8 9.4 11.9 17.5 2.9 3.9 21.4 3.8 24.3 8.1 4.0 4.1 4.3 14.4 4.8 4.9 2.5 4.5 7.3 1.1 8.4 19.9 1.5 3.2 15.6 7.0 3.2 2.3 5.0 6.7 5.8 8.5 3.5 10.6 0.8 4.1 11.3 13.1 3.9 36.9 3.7 15.2 0.8 7.6 7.0 15.8 82.6 54.0 67.8 40.8 19.4 3.9 1.8 7.4 61.0 28.9 7.7 11.7 105.4 16.4 1.6 6.2 0.5 28.3 127.6 16.6 1.3 2.9 13.6 2.1 105.9 41.3 28.8 66.0 3.7 17.3 0.2 13.5 46.6 3.5 0.6 0.9 8.2 29.7 2.5 4.1 2.8 3.7 0.5 2.0 3.6 8.3 0.9 74.4 9.1 3.0 5.1 108.9 105.8 20.8 82.3 142.1 1.7 0.4 1.6 80.5 6.5 16.1 1.5 1.9 0.0 0.7 0.9 0.2 0.0 0.1 0.2 0.5 0.1 0.0 0.1 0.2 0.0 0.2 4.8 0.0 0.8 4.0 3.0 2.1 3.9 2.9 3.9 4.0 4.1 4.5 2.3 8.5 3.9 22.0 0.0 0.0 1.0 2.8 12.6 57.0 18.6 2.8 1.5 31.1 29.1 5.3 47.1 6.6 1.8 0.0 1.2 9.1 1.0 0.0 105.4 0.2 15.3 13.5 51.2 0.0 22.3 0.5 12.7 16.9 27.5 3.1 60.7 7.0 0.4 4.2 0.2 30.1 33.7 1.6 2.4 6.1 8.9 45.4 1.4 3.7 39.9 12.4 1.0 61.5 165.1 3.1 0.0 0.1 101.8 1.2 19.9 3.5 68.9 0.8 2.5 2.0 3.9 0.0 17.3 54.3 0.0 9.5 6.7 10.7 1.4 4.2 0.8 0.4 27.0 SPIB SPI-B ENSG00000269404 "Spi-B transcription factor" Q01892 19 50418938-50431314 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 27.9;lymphoid tissue: 99.4" "Cell type enriched" "Detected in many" 4 "Paneth cells: 787.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 54 "memory B-cell: 307.8;naive B-cell: 260.6;plasmacytoid DC: 572.6" "Group enriched" "Detected in many" 106 "B-cells: 307.8;dendritic cells: 572.6" "Cell line enhanced" "Detected in some" "Daudi: 166.3;HDLM-2: 107.3;Karpas-707: 52.8;U-698: 238.2" HPA018523 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA018523: AB_1857443" "prognostic favorable (4.76e-5)" "unprognostic (1.06e-5)" "unprognostic (9.15e-3)" "unprognostic (3.70e-2)" "unprognostic (9.72e-3)" "prognostic favorable (2.14e-5)" "unprognostic (2.33e-1)" "unprognostic (4.79e-3)" "unprognostic (1.18e-2)" "unprognostic (7.85e-2)" "unprognostic (1.12e-1)" "unprognostic (1.50e-1)" "unprognostic (3.96e-8)" "unprognostic (1.43e-1)" "unprognostic (2.65e-2)" "unprognostic (1.75e-1)" "unprognostic (7.33e-2)" 1.2 0.1 0.4 41.7 0.5 6.1 0.2 1.3 0.6 0.1 0.5 22.2 13.1 0.4 0.2 0.7 0.8 1.6 0.2 0.4 0.6 0.6 0.5 1.0 87.0 1.4 0.2 0.1 1.5 0.0 0.1 0.2 0.5 1.2 18.2 0.2 2.7 0.2 1.3 0.5 27.9 0.8 0.1 29.3 8.2 0.4 0.4 7.6 0.8 0.2 99.4 4.1 0.3 1.4 0.4 1.1 0.1 0.1 0.0 0.0 0.7 0.1 0.0 0.1 0.2 3.1 0.2 166.3 0.2 0.1 0.0 0.2 1.4 0.0 0.0 107.3 0.3 0.7 0.3 0.1 0.0 0.5 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.8 4.6 52.8 0.1 0.5 0.1 0.6 1.5 0.1 0.0 11.6 0.9 2.0 0.0 0.2 0.1 0.1 0.1 0.2 0.2 0.2 0.3 5.4 0.8 0.1 3.0 0.1 0.3 5.0 3.5 238.2 0.1 2.6 0.2 4.1 0.5 0.8 0.5 0.2 0.4 307.8 0.3 0.3 6.9 260.6 0.4 0.3 2.6 3.9 0.3 572.6 0.6 14.8 0.4 0.5 1.3 0.6 0.4 0.6 1.4 0.2 0.5 0.1 0.4 1.4 0.5 0.0 1.8 0.3 162.7 1.8 2.1 0.0 0.0 0.7 0.6 0.9 0.4 0.0 0.0 0.0 0.0 0.3 192.8 28.3 0.0 0.7 0.0 1.1 0.3 0.8 19.8 0.4 0.3 1.1 0.2 1.1 2.6 0.5 4.5 0.2 0.0 0.5 1.4 0.0 0.3 18.4 0.0 0.6 38.0 0.0 0.0 13.0 7.2 0.0 1.6 0.6 1.0 0.0 0.2 0.0 787.8 0.4 2.0 1.4 5.0 0.3 0.7 1.0 0.0 1.3 0.8 0.2 1.1 0.0 1.3 0.3 2.7 0.1 37.6 1.3 SPINK1 "PCTT, PSTI, Spink3, TATI" ENSG00000164266 "Serine peptidase inhibitor Kazal type 1" P00995 5 147824572-147831671 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "pancreas: 53063.4" "Group enriched" "Detected in many" 9 "Exocrine glandular cells: 50621.7;Pancreatic endocrine cells: 16750.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 513.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "CACO-2: 417.2;RT4: 1139.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026366, HPA027498" Enhanced "Secreted to digestive system" NA NA 8000000 "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "CAB026366: , HPA027498: AB_10603115" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (9.96e-3)" "unprognostic (3.55e-1)" "unprognostic (6.12e-3)" "unprognostic (1.79e-4)" "unprognostic (8.34e-3)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "unprognostic (1.88e-1)" "unprognostic (3.82e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (5.44e-7)" "unprognostic (7.98e-2)" "unprognostic (2.07e-1)" "prognostic favorable (2.15e-5)" 8.8 1.5 0.1 36.4 0.1 6.8 4.1 0.3 1.2 3.1 0.3 428.2 394.4 5.5 0.8 2.9 1.3 111.9 12.0 0.2 0.2 142.5 491.8 2.7 2.7 0.1 0.1 25.6 53063.4 0.0 1.9 3.2 0.2 4.4 441.3 0.6 12.8 1.4 1.2 21.1 403.9 14.1 0.0 2.5 1475.2 0.9 0.3 0.4 1.0 0.0 0.3 995.6 10.8 0.6 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 417.2 0.3 0.1 6.8 0.0 0.8 0.9 2.2 0.0 0.0 3.9 0.0 0.0 0.0 107.0 0.3 0.0 3.9 0.0 2.1 0.0 3.0 5.8 0.0 0.0 0.0 0.3 0.0 0.3 0.8 1.3 2.1 138.9 0.8 0.8 0.0 2.5 0.0 1139.0 0.5 1.7 0.0 0.2 0.1 5.4 0.1 0.0 0.0 0.1 13.7 1.1 3.8 2.2 5.9 3.0 16.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 1.2 0.2 0.2 0.1 0.1 0.2 0.0 0.3 0.6 0.0 0.0 3.6 0.0 9.7 0.0 15.1 0.3 0.0 0.0 5.5 0.8 0.1 1451.2 11.1 377.0 0.0 0.0 0.0 280.8 86.1 1286.7 0.1 0.3 0.4 9.4 517.2 18.7 1.0 50621.7 0.1 1.9 1580.5 5.0 4.5 2.0 39.3 3385.8 0.1 0.0 0.2 2087.4 0.0 30.9 0.0 0.2 0.0 13.7 0.0 0.0 269.8 0.0 0.0 0.0 0.1 16750.7 563.8 0.0 1.3 173.5 1457.1 1.6 0.7 0.0 0.0 0.0 43.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 1365.3 649.1 SPINK13 "HESPINTOR, LiESP6, MGC149260, SPINK5L3" ENSG00000214510 "Serine peptidase inhibitor Kazal type 13" Q1W4C9 5 148268180-148286255 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "epididymis: 328.8" "Group enriched" "Detected in some" 6 "Leydig cells: 39.7;Peritubular cells: 26.7" "Cancer enhanced" "Detected in some" "renal cancer: 3.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "HeLa: 574.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036456 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA036456: AB_10673496" "unprognostic (5.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.22e-1)" "unprognostic (1.41e-2)" "unprognostic (6.43e-3)" "unprognostic (1.25e-3)" "unprognostic (5.01e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (4.03e-10)" "unprognostic (4.31e-2)" "unprognostic (1.72e-1)" "unprognostic (2.43e-1)" "unprognostic (2.95e-2)" 0.3 1.9 0.7 0.1 1.2 0.0 0.0 0.9 1.0 0.2 0.0 1.1 0.0 0.2 328.8 0.1 0.4 0.2 0.5 0.4 0.8 0.6 0.0 0.3 0.1 1.3 0.8 0.5 0.2 0.0 0.5 0.0 1.4 1.7 0.0 1.5 0.2 31.3 0.4 0.5 0.0 0.1 0.7 0.0 1.6 1.3 1.1 0.1 0.3 0.0 0.0 1.5 0.1 2.8 0.0 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 574.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.1 0.0 1.5 0.0 0.0 0.3 30.0 0.2 0.3 0.0 22.5 0.0 0.0 0.2 1.9 0.0 0.6 1.1 0.1 0.4 0.1 0.6 0.0 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.9 1.0 0.4 0.8 1.3 0.8 1.4 0.7 1.1 2.8 0.1 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 2.0 0.0 0.0 0.0 0.0 0.0 5.0 0.6 0.0 0.0 0.0 0.0 0.1 39.7 0.1 0.0 0.0 0.0 0.0 0.0 1.0 1.4 2.8 0.0 26.7 0.1 0.5 0.0 0.1 0.0 0.6 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPINK14 SPINK5L2 ENSG00000196800 "Serine peptidase inhibitor Kazal type 14 (putative)" Q6IE38 5 148169733-148175398 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.8;intestine: 1.0;liver: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "OE19: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 65: Brain - Ion transport" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" "unprognostic (4.98e-2)" "unprognostic (3.44e-1)" "unprognostic (1.94e-2)" "unprognostic (2.96e-2)" "unprognostic (5.69e-1)" "unprognostic (1.48e-3)" 0.0 0.0 2.3 0.0 1.3 0.0 0.8 0.5 3.3 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.6 0.0 1.1 0.1 0.0 1.6 1.0 0.0 0.0 0.0 0.0 0.2 2.5 0.1 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.3 0.5 3.3 0.9 0.6 1.6 1.0 2.5 1.0 1.4 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 SPINK2 HUSI-II ENSG00000128040 "Serine peptidase inhibitor Kazal type 2" P20155 4 56809860-56821742 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "epididymis: 5310.4" "Group enriched" "Detected in many" 10 "Early spermatids: 1217.2;Late spermatids: 1399.4;Spermatocytes: 1989.6" "Group enriched" "Detected in some" 5 "lung cancer: 1.3;testis cancer: 4.6;thyroid cancer: 2.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "NK-cell: 146.4" "Lineage enriched" "Detected in many" 7 "NK-cells: 146.4" "Cell line enriched" "Detected in some" 4 "U-266/70: 90.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB020824, HPA026813" Enhanced "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB020824: , HPA026813: AB_1857446" "unprognostic (5.56e-3)" "unprognostic (3.60e-1)" "unprognostic (7.54e-2)" "unprognostic (2.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.60e-1)" "prognostic favorable (2.82e-4)" "unprognostic (9.83e-2)" "unprognostic (6.62e-2)" "unprognostic (9.40e-3)" "unprognostic (2.06e-1)" "unprognostic (2.49e-1)" "unprognostic (4.10e-3)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.87e-2)" 0.5 0.1 0.1 1.1 0.2 13.5 1.3 0.1 0.6 1.3 1.8 2.8 1.9 0.3 5310.4 0.2 0.3 0.1 7.4 0.2 0.2 0.3 0.2 0.2 4.7 0.3 0.3 0.4 0.1 0.0 4.2 0.0 0.2 3.5 2.1 0.0 2.0 240.7 1.8 0.5 3.1 0.3 0.2 1.7 3.0 346.1 0.3 3.9 0.6 2.3 4.8 0.5 4.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.7 2.9 18.0 0.5 0.0 0.0 0.0 0.0 4.5 0.0 6.0 0.3 3.0 0.0 0.0 0.2 0.7 0.0 0.4 0.0 0.0 0.0 0.2 0.0 90.5 0.4 0.0 0.0 0.0 0.0 4.4 0.0 1.1 0.5 0.1 0.6 9.1 5.1 5.4 1.4 10.5 11.1 21.6 0.9 146.4 0.0 0.8 0.3 5.4 0.1 0.2 0.1 0.6 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.1 0.2 0.0 0.0 0.0 7.2 2.0 14.2 1.8 1.8 0.0 0.2 0.6 3.4 0.0 0.2 0.0 0.0 0.0 2.5 1.4 0.0 0.0 1217.2 0.2 0.1 1.6 1.8 32.4 0.3 0.0 0.3 0.8 0.5 0.2 1.3 0.3 0.0 0.0 0.1 0.0 0.2 10.4 0.0 0.0 3.6 1399.4 37.9 2.5 12.4 0.0 1.6 1.5 1.0 0.0 0.1 0.0 13.1 24.5 35.2 9.5 0.4 0.3 0.3 0.0 13.1 0.4 1.9 1989.6 149.9 0.1 0.3 0.0 16.8 0.0 2.6 2.6 SPINK4 "MGC133107, PEC-60" ENSG00000122711 "Serine peptidase inhibitor Kazal type 4" O60575 9 33218365-33248567 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 980.5" "Cell type enriched" "Detected in some" 14 "Intestinal goblet cells: 8017.1" "Group enriched" "Detected in many" 20 "colorectal cancer: 237.5;pancreatic cancer: 269.7;stomach cancer: 111.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 1.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.8" "Group enriched" "Detected in some" 12 "HMC-1: 175.7;OE19: 480.7" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Low region specificity" "Detected in single" HPA007286 Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Secreted to digestive system" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Vesicles" Nucleoplasm "HPA007286: AB_1080083" "unprognostic (3.49e-2)" "unprognostic (2.32e-1)" "prognostic favorable (8.85e-5)" "unprognostic (3.09e-4)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (9.66e-2)" "unprognostic (2.43e-1)" "unprognostic (1.24e-1)" "unprognostic (3.25e-1)" "unprognostic (2.42e-3)" 1.4 0.6 0.0 84.2 0.0 0.6 0.1 0.7 0.3 0.0 0.1 639.5 263.4 1.8 0.0 0.1 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.0 0.7 0.1 0.1 0.0 0.9 2.1 0.9 0.0 0.1 0.0 980.5 92.1 0.1 0.5 0.2 0.1 638.1 42.2 0.0 0.2 1.4 0.3 0.0 0.1 0.0 0.0 0.0 17.4 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.0 0.0 0.0 3.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 11.7 27.8 1.1 0.0 0.0 175.7 0.0 0.0 0.0 0.4 0.5 0.0 0.1 4.1 0.3 0.0 3.9 0.4 2.3 0.0 480.7 0.4 0.0 0.0 0.2 0.0 0.5 0.4 1.4 15.2 3.1 0.0 0.1 14.2 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.3 0.1 1.4 0.3 0.0 1.8 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.3 0.0 0.0 0.0 21.7 0.1 0.0 0.0 0.0 0.0 5.5 12.5 0.1 0.0 56.5 0.0 0.2 1.0 0.1 0.0 0.6 88.2 0.0 0.0 0.0 0.0 0.0 43.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8017.1 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.9 0.0 0.5 0.1 0.1 106.8 0.0 0.1 0.2 541.4 0.0 0.0 129.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.1 191.5 0.2 SPINK5 "DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI" ENSG00000133710 "Serine peptidase inhibitor Kazal type 5" Q9NQ38 5 148025683-148137382 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 338.5;esophagus: 1015.0;skin 1: 318.2;vagina: 582.6" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 1622.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 45.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 14.7;HeLa: 22.7;Karpas-707: 19.3;SuSa: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009067, HPA011351, CAB015347" Enhanced Enhanced Vesicles "Secreted in other tissues" NA NA 43000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB015347: AB_2196138, HPA009067: AB_1080084, HPA011351: AB_1857447" "unprognostic (9.66e-3)" "unprognostic (1.42e-2)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.42e-3)" "unprognostic (2.45e-2)" "unprognostic (6.85e-2)" "unprognostic (1.16e-1)" "unprognostic (2.28e-2)" "unprognostic (4.92e-3)" "unprognostic (4.56e-1)" "unprognostic (2.44e-1)" "unprognostic (7.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.87e-2)" "unprognostic (2.59e-1)" 1.1 0.3 0.0 0.5 0.1 0.0 17.5 0.0 0.2 338.5 0.0 4.8 0.3 0.6 0.3 1015.0 0.4 1.8 1.7 0.1 0.0 0.8 0.4 2.0 0.1 0.1 0.1 0.3 0.8 1.0 2.0 2.4 0.2 1.3 10.6 0.0 145.0 0.5 1.8 318.2 0.6 0.4 0.0 0.3 5.0 1.6 0.1 9.1 2.2 1.1 292.9 0.7 582.6 0.3 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.2 1.8 0.0 0.0 14.7 0.0 1.3 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.3 0.0 0.0 3.9 0.0 0.0 0.0 0.2 0.0 0.9 19.3 0.0 2.1 0.0 0.0 2.6 2.0 0.3 0.0 0.0 0.0 0.0 5.7 2.8 0.0 0.6 0.0 0.0 6.6 4.6 0.0 0.0 0.0 0.1 0.0 0.0 5.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 5.7 9.6 45.4 0.3 0.2 53.7 1.5 331.1 102.4 0.0 4.2 3.4 1.2 34.3 115.6 0.0 0.0 1.9 0.0 177.9 0.0 0.2 11.0 2.5 0.7 12.9 4.2 0.0 0.7 1.3 2.1 2.6 17.9 4.8 1.3 0.0 7.9 0.2 0.1 0.0 0.8 33.8 16.2 0.8 2.1 3.8 0.6 0.7 3.6 2.8 0.0 0.0 0.0 2.0 1.2 7.6 60.3 0.0 3.7 0.7 0.0 0.0 9.4 0.0 0.0 0.2 2.4 1.3 4.6 1622.6 64.4 1.5 1.1 1.0 97.9 2.7 SPINK6 "BUSI2, MGC21394, UNQ844" ENSG00000178172 "Serine peptidase inhibitor Kazal type 6" Q6UWN8 5 148202794-148215137 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 5.7;lymphoid tissue: 4.9;salivary gland: 6.9;vagina: 10.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.5;Hofbauer cells: 2.8;Oligodendrocyte precursor cells: 1.0;Prostatic glandular cells: 5.2" "Group enriched" "Detected in many" 6 "cervical cancer: 21.4;head and neck cancer: 21.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 74 "HeLa: 3708.0;SiHa: 2339.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA011039 Uncertain "Secreted - unknown location" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "HPA011039: AB_2668412" "unprognostic (2.92e-2)" "unprognostic (2.97e-2)" "unprognostic (2.65e-1)" "unprognostic (4.87e-2)" "prognostic favorable (7.16e-4)" "unprognostic (2.49e-2)" "unprognostic (4.04e-1)" "unprognostic (1.80e-2)" "unprognostic (2.09e-2)" "unprognostic (2.22e-2)" "unprognostic (1.29e-2)" "unprognostic (7.29e-2)" 0.6 0.2 0.1 0.0 0.7 0.0 0.2 3.0 1.1 5.7 0.1 1.7 0.0 0.0 1.2 2.4 0.0 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.5 0.3 6.9 0.0 0.0 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.4 4.9 0.0 0.1 0.0 0.6 10.1 2.1 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.5 3708.0 4.0 0.0 0.6 0.0 0.0 28.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.3 0.0 0.0 1.0 0.0 0.0 2339.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.3 40.8 0.2 0.1 0.0 0.7 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 3.0 1.1 0.4 0.1 0.6 0.4 0.9 0.1 0.4 2.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 2.8 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.4 0.0 5.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 SPINK7 "ECG2, ECRG2" ENSG00000145879 "Serine peptidase inhibitor Kazal type 7" P58062 5 148312419-148315922 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 256.8;esophagus: 620.4;vagina: 614.0" "Cell type enriched" "Detected in some" 7 "Squamous epithelial cells: 49.2" "Group enriched" "Detected in many" 6 "cervical cancer: 4.5;head and neck cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036294 Enhanced "Secreted in other tissues" NA NA 230000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA036294: AB_10671243" "unprognostic (2.82e-1)" "unprognostic (8.99e-3)" "unprognostic (8.52e-3)" "unprognostic (1.81e-1)" "unprognostic (1.12e-2)" "unprognostic (3.37e-2)" "unprognostic (9.10e-2)" "unprognostic (1.49e-1)" "unprognostic (6.86e-2)" "unprognostic (7.24e-2)" "unprognostic (4.22e-2)" 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.3 256.8 0.1 0.1 0.0 0.1 0.1 620.4 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.7 0.0 0.3 0.1 0.0 0.0 140.1 0.0 0.2 9.3 0.1 0.1 0.1 0.1 4.2 0.1 0.2 4.7 0.1 0.1 115.9 0.6 614.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.3 0.1 0.2 0.1 0.2 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.2 0.0 0.0 0.0 0.0 0.0 4.5 SPINK9 ENSG00000204909 "Serine peptidase inhibitor Kazal type 9" Q5DT21 5 148321203-148339852 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 16.0;Alveolar cells type 2: 27.9;Club cells: 14.9;granulocytes: 10.1;Respiratory ciliated cells: 14.6" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 12.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 24.4;U-266/84: 26.9" "Low region specificity" "Detected in single" HPA038288 Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA 24000 "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Vesicles" "HPA038288: AB_10795400" "unprognostic (1.84e-1)" "unprognostic (4.87e-3)" "unprognostic (2.88e-1)" "unprognostic (9.02e-2)" "unprognostic (5.49e-3)" "unprognostic (3.04e-2)" "unprognostic (3.04e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (2.82e-2)" "unprognostic (1.91e-2)" "unprognostic (3.93e-1)" "unprognostic (2.01e-1)" "unprognostic (3.99e-2)" "unprognostic (1.90e-1)" 1.5 3.2 17.1 3.0 13.7 6.5 0.5 19.2 26.6 0.6 5.0 2.0 2.2 2.6 1.9 2.2 1.0 1.4 2.0 14.6 10.6 1.8 1.6 1.1 2.6 10.0 6.1 1.8 1.1 0.5 0.1 3.2 10.8 2.5 1.7 10.3 1.5 0.5 3.8 3.4 2.4 0.5 2.6 1.9 2.4 4.2 11.5 3.2 1.5 0.1 1.6 0.9 0.0 28.0 15.4 2.6 2.9 3.4 0.7 1.2 2.8 3.5 0.2 0.3 0.5 5.3 10.8 3.4 24.4 0.1 2.0 3.5 0.9 0.7 1.0 6.1 1.4 7.7 8.3 2.7 0.3 2.9 2.6 0.2 0.7 0.5 0.1 2.0 0.0 2.5 4.9 18.3 0.4 9.6 2.5 4.7 13.7 5.5 5.0 3.9 3.4 4.0 1.0 10.0 6.3 7.9 3.0 8.6 2.8 8.6 14.0 3.0 5.9 4.4 14.1 3.9 4.5 11.1 26.9 4.0 2.6 2.1 6.2 12.4 1.8 1.0 1.1 1.0 1.4 0.8 1.3 1.4 0.4 1.9 1.8 1.8 6.6 3.9 2.2 1.9 0.9 0.1 17.1 13.7 19.2 26.6 14.6 10.6 10.0 6.1 10.8 2.6 11.5 28.0 0.1 16.0 27.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.4 0.0 14.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 1.9 0.0 0.0 0.3 0.0 0.0 2.6 0.0 0.1 10.1 0.1 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 2.2 0.4 0.0 0.1 0.0 0.3 14.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.7 0.0 0.0 0.2 SPINT1 "HAI, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 255.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1254.0;Distal enterocytes: 477.6;Proximal enterocytes: 514.5;Syncytiotrophoblasts: 1673.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 323.2;HaCaT: 377.6;hTCEpi: 264.0;RT4: 308.2;SK-BR-3: 558.8;T-47d: 267.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 7400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" 2.8 0.7 0.9 16.4 1.5 1.4 34.7 5.0 1.3 42.8 6.4 108.7 159.9 13.2 78.9 255.5 33.6 38.0 1.3 0.9 2.0 79.9 3.5 47.6 6.4 2.8 3.2 2.4 69.2 132.9 31.4 144.9 2.2 52.3 89.2 0.4 162.7 31.4 0.6 148.9 138.2 4.3 1.7 6.9 88.3 1.8 3.2 9.9 34.7 0.4 45.5 57.1 90.1 2.3 124.8 1.0 0.0 0.9 0.1 0.0 323.2 2.3 3.0 4.0 2.4 195.3 202.4 0.3 141.2 0.4 3.6 377.6 30.8 181.9 2.4 1.0 10.6 5.6 3.3 10.8 2.2 21.9 93.9 0.3 264.0 3.9 16.5 3.4 14.7 12.1 2.7 1.1 0.2 96.5 0.9 16.6 37.4 207.6 17.7 12.6 0.0 24.9 179.3 308.2 79.8 3.9 9.3 558.8 15.7 56.9 267.7 16.1 0.0 0.2 2.0 1.2 0.5 1.2 24.5 0.8 0.8 16.3 1.1 0.0 19.7 14.3 0.4 15.9 0.8 8.4 3.0 1.4 32.4 6.0 1.1 0.3 25.9 5.5 18.1 4.0 0.5 7.6 0.9 1.5 5.0 1.3 0.9 2.0 2.8 3.2 2.2 1.7 3.2 2.3 0.8 57.7 14.7 0.0 7.6 76.0 96.7 220.0 55.8 0.1 96.2 63.5 0.5 105.8 207.3 134.3 0.0 1254.0 1.4 477.6 25.4 429.4 0.8 63.3 14.2 6.9 147.3 4.8 0.5 255.1 105.1 10.4 106.5 155.6 10.2 1.9 0.4 0.5 135.4 0.0 0.5 169.4 221.8 10.0 23.8 1.1 3.7 19.8 14.2 0.0 68.6 0.0 0.0 0.0 0.0 309.8 375.2 0.0 2.1 135.7 514.5 44.2 46.6 0.3 0.0 0.1 12.6 0.6 5.9 93.2 87.9 1673.8 6.6 0.1 182.7 222.3 SPINT2 "HAI-2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1371.3;Syncytiotrophoblasts: 1413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 852.5;CAPAN-2: 1219.1;OE19: 1500.4;RPTEC TERT1: 896.7;SK-BR-3: 789.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011101, CAB018969" Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Intermediate filaments, Cytosol" "CAB018969: , HPA011101: AB_1079039" "unprognostic (5.13e-2)" "unprognostic (1.06e-3)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.04e-1)" "prognostic favorable (3.41e-4)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" 10.5 44.6 56.9 65.3 57.3 81.1 178.5 47.2 66.3 145.6 80.0 297.0 247.4 44.6 269.6 351.9 189.7 105.1 13.6 58.9 92.9 216.1 14.3 138.3 37.4 52.0 54.8 83.3 234.2 252.9 435.9 156.4 56.2 181.8 251.7 23.6 503.9 111.3 1.8 257.0 267.0 19.0 47.6 50.2 219.4 215.7 70.3 82.6 321.3 0.9 101.3 140.1 157.6 51.0 852.5 603.0 3.0 3.4 0.4 0.0 387.4 16.2 1.7 1.2 2.6 426.8 1219.1 6.7 65.8 4.6 1.2 274.6 42.7 587.0 1.4 7.9 51.7 159.4 15.3 0.9 0.9 1.5 0.8 0.1 662.5 0.7 278.6 71.5 2.0 144.2 4.0 0.4 1.0 652.8 25.6 2.8 60.4 1500.4 172.1 87.9 0.6 386.2 896.7 707.4 222.2 3.4 246.5 789.2 2.1 231.0 353.7 104.5 0.7 1.2 4.7 3.4 3.2 56.1 76.4 47.6 1.0 11.2 1.0 515.9 127.4 531.9 3.8 91.1 7.9 143.2 44.2 21.5 297.7 160.4 86.1 80.4 56.4 19.0 64.4 523.5 19.1 142.8 56.9 57.3 47.2 66.3 58.9 92.9 52.0 54.8 56.2 47.6 70.3 51.0 8.0 368.6 233.9 10.4 90.9 376.9 563.9 954.0 278.9 14.3 487.2 518.2 2.8 316.0 655.6 559.1 6.2 1371.3 79.5 1028.3 101.8 866.9 61.8 401.4 47.3 24.3 360.5 83.9 20.7 659.8 502.0 34.6 234.5 490.4 115.5 371.8 32.5 2.0 230.3 3.3 39.8 672.8 734.5 55.5 139.0 55.6 19.0 133.6 88.9 24.4 364.3 129.6 1.0 4.5 9.0 910.4 889.4 17.0 61.3 684.9 918.6 208.8 495.1 17.2 52.6 1.2 76.7 545.2 264.1 507.7 428.3 1413.2 42.6 3.4 582.2 989.6 SPINT3 HKIB9 ENSG00000101446 "Serine peptidase inhibitor, Kunitz type 3" P49223 20 45512461-45515622 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 4.8;seminal vesicle: 10.7" "Group enriched" "Detected in some" 4 "Basal prostatic cells: 1.5;Endometrial ciliated cells: 1.4;Glandular and luminal cells: 4.0;Suprabasal keratinocytes: 2.3;Urothelial cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA026852 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 44: Endometrium - Transcription" "HPA026852: AB_2732434" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.7 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.4 SPINT4 "C20orf137, dJ601O1.1" ENSG00000149651 "Serine peptidase inhibitor, Kunitz type 4" Q6UDR6 20 45722347-45725830 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 255 "epididymis: 278.8" "Cell type enriched" "Detected in single" 9 "Rod photoreceptor cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.0" "Not detected" "Not detected" HPA046703 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA046703: AB_2732530" "unprognostic (3.61e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 278.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.4 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPOCK1 "SPOCK, testican-1, TIC1" ENSG00000152377 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1" Q08629 5 136975298-137598379 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 172.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 252.8;Inhibitory neurons: 349.9;Muller glia cells: 243.8;Oligodendrocyte precursor cells: 273.4;Oligodendrocytes: 913.1;Peritubular cells: 150.1" "Cancer enriched" "Detected in all" 7 "prostate cancer: 83.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 573.1;hTERT-RPE1: 1112.8;HUVEC TERT2: 594.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007450, HPA026770" Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA007450: AB_10603116, HPA026770: " "unprognostic (1.05e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (1.58e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.83e-3)" "prognostic unfavorable (9.08e-4)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.72e-4)" "unprognostic (9.09e-3)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.77e-5)" "prognostic unfavorable (9.40e-4)" "unprognostic (1.26e-1)" "unprognostic (2.21e-1)" "unprognostic (1.90e-2)" 29.7 41.4 67.9 4.1 116.3 0.3 19.0 129.2 99.5 25.6 9.9 24.9 1.2 44.2 34.3 6.1 18.6 18.6 54.2 100.5 50.9 24.3 0.2 2.9 0.6 80.7 84.5 4.8 5.5 13.7 9.9 9.3 89.8 65.6 3.2 48.7 7.6 25.5 17.5 9.3 4.6 30.7 78.4 8.5 9.1 21.7 102.6 7.5 9.4 7.1 0.4 11.4 21.7 172.9 4.6 0.9 299.4 0.4 573.1 116.0 0.4 100.6 90.0 207.7 115.9 0.0 0.6 0.4 0.2 206.7 53.3 4.4 1.4 70.3 65.3 17.8 0.6 0.2 16.7 0.0 4.0 0.0 0.4 203.8 28.5 128.6 23.2 1112.8 594.4 0.2 0.0 0.4 60.5 0.5 0.0 0.2 19.1 0.0 28.4 0.0 0.2 0.0 140.3 9.4 3.7 14.4 49.9 0.8 0.1 35.6 0.4 1.2 98.9 294.0 10.6 102.1 28.5 0.1 0.1 0.1 159.4 4.4 136.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 67.9 116.3 129.2 99.5 100.5 50.9 80.7 84.5 89.8 78.4 102.6 172.9 2.0 0.0 0.0 91.7 0.0 1.8 1.6 5.8 0.0 9.7 0.4 0.4 58.8 1.5 0.4 22.0 2.1 0.4 0.0 0.2 1.9 0.6 12.0 4.2 37.9 8.4 35.0 0.0 252.8 1.4 0.3 58.8 0.0 2.9 0.0 0.1 1.1 0.0 0.9 8.4 349.9 0.1 16.2 1.2 3.0 9.5 17.4 1.6 7.2 17.8 2.3 243.8 0.0 273.4 913.1 2.0 0.1 150.1 0.1 40.9 0.0 3.1 0.9 7.3 13.1 11.6 16.4 7.4 7.1 0.7 1.4 0.1 0.4 0.0 0.3 3.2 SPOCK2 "KIAA0275, testican-2" ENSG00000107742 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2" Q92563 10 72059034-72089032 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 220.1;lymphoid tissue: 114.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 288.4;Bipolar cells: 116.5;dendritic cells: 86.4;Inhibitory neurons: 81.1;Microglial cells: 75.9;NK-cells: 90.6;T-cells: 195.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 117.5;MAIT T-cell: 198.8;memory CD4 T-cell: 115.9;memory CD8 T-cell: 93.5;naive CD4 T-cell: 87.8;naive CD8 T-cell: 89.4;T-reg: 174.3" "Lineage enriched" "Detected in all" 8 "T-cells: 198.8" "Group enriched" "Detected in some" 7 "Hep G2: 50.2;SCLC-21H: 68.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044605 Enhanced "Secreted to blood" NA NA 34000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "HPA044605: AB_10965991" "prognostic favorable (4.05e-4)" "unprognostic (3.11e-3)" "unprognostic (2.92e-2)" "unprognostic (2.29e-1)" "unprognostic (2.77e-2)" "prognostic favorable (1.95e-5)" "unprognostic (4.18e-2)" "unprognostic (9.04e-2)" "prognostic favorable (4.72e-4)" "prognostic unfavorable (7.19e-4)" "unprognostic (4.53e-3)" "unprognostic (2.29e-1)" "unprognostic (1.46e-3)" "unprognostic (5.59e-2)" "unprognostic (5.49e-2)" "unprognostic (3.19e-3)" "unprognostic (2.24e-2)" 9.4 46.6 152.6 44.5 108.0 58.1 3.8 160.4 143.2 4.2 2.8 7.6 9.2 4.0 3.1 3.3 6.2 15.3 10.0 117.4 150.1 68.0 2.7 86.5 67.3 212.1 157.7 7.1 1.6 2.0 44.0 3.4 220.1 4.7 5.4 33.4 3.3 5.6 5.1 1.8 32.3 4.4 127.9 29.1 13.6 25.1 207.3 114.4 10.4 6.7 45.3 9.9 3.8 95.6 0.2 0.4 0.3 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 8.2 0.3 1.4 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.8 0.2 1.4 50.2 1.6 0.4 1.2 0.1 0.4 0.0 0.0 0.2 0.1 2.7 0.1 0.8 0.0 0.3 0.9 0.3 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.3 68.2 4.1 0.1 1.5 0.4 0.3 0.0 1.9 0.2 0.0 0.3 0.3 0.1 0.7 1.7 7.3 0.3 0.1 0.2 0.6 0.4 0.2 117.5 1.2 198.8 23.6 115.9 93.5 0.3 18.3 87.8 89.4 13.5 14.4 0.4 3.5 174.3 48.4 152.6 108.0 160.4 143.2 117.4 150.1 212.1 157.7 220.1 127.9 207.3 95.6 17.3 288.4 10.0 51.9 54.6 3.8 0.4 2.1 0.0 116.5 1.9 2.0 3.1 1.5 4.1 14.7 6.2 0.1 86.4 2.4 0.0 3.6 8.1 2.5 1.0 29.9 4.9 3.6 39.6 0.8 0.1 8.4 3.6 1.0 3.8 0.2 7.9 0.4 0.2 3.3 81.1 1.3 2.0 1.6 7.9 10.5 5.3 5.5 5.4 75.9 4.1 5.0 90.6 28.6 8.3 0.0 4.4 6.0 34.2 0.5 0.1 0.5 2.4 17.6 0.0 17.9 2.4 6.3 1.1 0.5 4.4 0.4 195.1 0.8 0.7 0.3 SPOCK3 testican-3 ENSG00000196104 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3" Q9BQ16 4 166733384-167234796 "Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 143.9;parathyroid gland: 175.0;prostate: 73.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 1010.6;Oligodendrocyte precursor cells: 399.1;Oligodendrocytes: 1851.1" "Cancer enhanced" "Detected in many" "prostate cancer: 7.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.2;myeloid DC: 1.8" "Group enriched" "Detected in many" 12 "dendritic cells: 1.8;monocytes: 1.2" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.2;hTERT-RPE1: 6.5;PC-3: 2.7;RH-30: 7.1;SCLC-21H: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.54e-2)" "unprognostic (8.69e-2)" "unprognostic (2.90e-3)" "unprognostic (1.20e-1)" "unprognostic (4.09e-4)" "unprognostic (3.75e-1)" "unprognostic (1.97e-2)" "unprognostic (1.44e-1)" "unprognostic (1.88e-1)" "unprognostic (3.94e-4)" "unprognostic (8.92e-2)" "unprognostic (4.18e-3)" "unprognostic (2.62e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-3)" "unprognostic (1.64e-1)" 0.3 24.7 51.4 0.6 87.2 0.1 0.3 73.0 97.3 0.9 18.7 0.9 0.8 2.9 18.8 0.2 1.1 0.3 0.3 48.4 63.8 0.2 0.4 0.4 0.5 83.2 64.9 17.4 0.7 175.0 0.3 0.0 79.4 73.9 0.5 14.3 0.3 34.9 0.2 0.0 1.3 2.8 72.8 0.4 0.7 0.5 68.4 0.3 0.2 24.0 0.3 1.7 0.2 143.9 0.0 1.6 0.2 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.4 0.1 0.2 0.0 1.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 6.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 2.7 0.0 7.1 0.4 0.0 1.1 2.8 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.5 51.4 87.2 73.0 97.3 48.4 63.8 83.2 64.9 79.4 72.8 68.4 143.9 0.0 0.0 0.0 12.7 0.1 0.0 1.5 8.1 0.0 43.7 0.0 0.0 1.6 0.0 10.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 15.0 0.0 0.2 1.6 0.0 1.3 106.7 0.0 0.1 15.7 2.0 0.0 1.3 3.2 0.0 0.0 0.1 15.2 1010.6 0.0 6.1 0.0 0.0 2.9 0.9 0.5 0.0 98.4 0.2 1.3 0.0 399.1 1851.1 0.1 0.0 0.4 0.0 3.3 0.0 0.1 6.7 6.3 0.0 0.0 2.5 0.5 0.7 0.0 0.0 0.1 0.0 55.4 0.0 0.8 SPON1 "f-spondin, KIAA0762" ENSG00000262655 "Spondin 1" Q9HCB6 11 13962723-14268133 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 101.4" "Cell type enhanced" "Detected in many" "Astrocytes: 399.9;Endometrial stromal cells: 78.9;Muller glia cells: 141.9" "Cancer enriched" "Detected in all" 5 "ovarian cancer: 199.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 3.3" "Lineage enriched" "Detected in single" 33 "T-cells: 3.3" "Group enriched" "Detected in some" 36 "EFO-21: 213.7;RPTEC TERT1: 604.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038584, HPA077546" Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments,Microtubule ends,Cytokinetic bridge" "Secreted to blood" Yes No 11500000 28000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Microtubule ends" "Nucleoplasm, Actin filaments, Cytokinetic bridge" "HPA038584: AB_10697394, HPA077546: AB_2732351" "unprognostic (1.66e-1)" "unprognostic (1.03e-2)" "unprognostic (8.36e-2)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (3.76e-2)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (1.05e-1)" "unprognostic (5.93e-2)" "unprognostic (6.45e-2)" "unprognostic (1.07e-1)" "prognostic favorable (3.12e-4)" "unprognostic (7.22e-3)" "unprognostic (7.89e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (1.88e-4)" 54.2 16.9 25.8 18.6 33.7 0.1 19.5 26.3 22.3 43.8 7.8 31.8 31.6 36.5 15.2 17.3 63.1 101.4 30.6 28.2 28.3 12.2 2.0 49.2 1.6 25.6 33.6 23.9 4.6 0.8 10.0 41.3 26.4 16.9 46.6 63.8 7.0 8.8 0.8 8.8 28.4 46.9 14.9 8.3 28.8 2.5 34.0 1.7 5.2 1.6 1.2 51.5 12.5 21.8 0.1 0.1 0.4 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 9.8 0.2 0.2 213.7 0.0 0.2 0.4 0.0 0.0 0.0 0.3 1.9 0.0 0.1 0.1 0.0 0.0 0.1 11.4 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.0 0.1 1.7 0.0 0.1 604.1 0.1 0.1 0.2 0.0 0.0 0.0 4.1 0.0 0.1 2.6 0.2 0.7 0.5 0.3 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.6 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.8 33.7 26.3 22.3 28.2 28.3 25.6 33.6 26.4 14.9 34.0 21.8 0.2 0.0 2.3 399.9 13.5 0.0 17.3 0.0 1.2 13.5 2.0 5.5 1.9 5.7 0.0 0.0 2.1 3.4 4.8 38.9 3.9 4.3 1.5 36.1 78.9 2.5 16.7 0.0 17.0 2.0 4.2 41.2 0.5 61.5 2.5 1.8 2.5 0.2 1.9 1.7 16.8 24.0 0.0 0.3 0.0 1.3 4.4 1.0 0.0 11.2 0.5 141.9 20.6 62.4 1.6 6.8 20.6 30.1 0.9 9.0 18.4 2.1 0.7 26.8 6.6 5.8 7.0 0.4 0.8 0.6 0.0 4.9 7.8 1.1 40.9 9.4 SPON2 DIL1 ENSG00000159674 "Spondin 2" Q9BUD6 4 1166932-1208962 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 187.1" "Cell type enhanced" "Detected in many" "dendritic cells: 427.0;Endometrial stromal cells: 256.6;Extravillous trophoblasts: 355.8;Fibroblasts: 257.7;NK-cells: 1096.8" "Cancer enriched" "Detected in all" 7 "prostate cancer: 243.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 255.9" "Lineage enriched" "Detected in all" 5 "T-cells: 255.9" "Group enriched" "Detected in many" 5 "HHSteC: 303.8;HSkMC: 546.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040170, HPA066095" Approved Approved Vesicles "Secreted to blood" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040170: AB_2676868, HPA066095: AB_2685615" "unprognostic (1.22e-1)" "unprognostic (3.56e-1)" "unprognostic (3.07e-2)" "prognostic favorable (2.03e-4)" "unprognostic (7.64e-2)" "unprognostic (6.28e-2)" "unprognostic (2.70e-3)" "unprognostic (2.28e-3)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-2)" "unprognostic (2.74e-3)" "unprognostic (1.22e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (9.22e-4)" 66.2 40.4 4.0 18.8 7.7 19.5 50.6 15.6 3.9 161.4 3.5 51.5 18.5 187.1 4.4 40.6 49.7 32.2 35.5 3.5 0.8 37.1 79.1 63.0 3.9 2.9 1.7 34.4 18.7 0.9 15.1 19.2 3.5 111.8 7.2 0.7 28.8 8.4 19.1 38.3 63.5 42.7 0.2 26.9 43.8 4.7 1.8 1.8 16.3 6.6 1.0 68.4 94.0 1.5 0.4 0.6 0.0 0.0 10.2 79.0 3.0 6.2 5.0 0.8 1.0 0.0 0.1 1.8 9.7 26.9 0.9 45.0 0.0 0.2 0.0 0.3 0.1 0.2 3.0 12.7 303.8 0.2 1.5 546.6 0.0 0.6 0.0 0.0 0.0 4.1 0.3 9.2 0.0 0.3 5.3 12.2 3.5 9.7 0.7 1.0 3.3 7.9 0.0 0.0 1.7 1.1 1.1 0.0 2.9 1.7 0.4 1.5 0.1 0.2 0.9 20.5 0.0 1.3 2.7 0.6 0.1 6.5 0.0 3.7 0.9 1.0 255.9 1.1 5.5 0.7 33.1 105.8 0.4 1.0 14.4 96.8 9.8 50.4 2.2 42.9 0.1 123.2 4.0 7.7 15.6 3.9 3.5 0.8 2.9 1.7 3.5 0.2 1.8 1.5 9.8 0.0 5.6 1.3 6.6 36.8 2.0 82.5 2.2 3.7 5.1 3.8 4.0 24.3 43.0 1.8 0.0 3.4 427.0 9.7 1.9 3.8 0.2 12.7 256.6 5.7 13.8 4.0 8.4 1.3 355.8 257.7 10.7 6.6 6.3 0.2 15.4 40.4 12.8 0.0 0.6 9.7 73.2 5.8 15.4 0.5 29.8 9.5 26.6 6.5 9.2 0.9 1096.8 0.5 0.7 1.5 6.7 9.4 64.0 15.8 16.3 28.3 32.6 0.4 6.6 22.5 89.9 0.2 0.5 21.3 21.5 38.9 100.8 8.1 7.9 13.2 SPOUT1 "C9orf114, CENP-32, HSPC109" ENSG00000198917 "SPOUT domain containing methyltransferase 1" Q5T280 9 128819651-128829794 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.0;Extravillous trophoblasts: 25.2;Granulosa cells: 32.5;Hofbauer cells: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076946 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "HPA076946: " "unprognostic (1.85e-1)" "unprognostic (3.51e-3)" "unprognostic (1.76e-2)" "unprognostic (3.32e-3)" "unprognostic (8.01e-2)" "unprognostic (1.66e-1)" "unprognostic (6.41e-3)" "unprognostic (5.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.27e-1)" "prognostic favorable (4.09e-4)" "unprognostic (1.44e-2)" "unprognostic (1.42e-2)" "unprognostic (1.98e-2)" "unprognostic (2.88e-1)" "unprognostic (1.09e-2)" "unprognostic (3.70e-2)" 17.0 19.0 20.8 14.3 21.4 13.5 18.3 20.2 25.6 20.0 19.1 18.3 11.2 17.6 5.7 25.7 19.9 9.1 21.2 20.0 20.8 26.0 45.1 16.8 18.9 20.6 20.9 20.0 22.9 9.1 20.6 9.5 19.9 32.7 5.5 6.5 18.7 8.6 20.6 23.7 20.6 8.1 19.4 30.8 22.9 13.2 21.4 13.4 22.8 6.0 10.3 22.8 19.8 21.6 13.7 31.2 25.2 37.2 14.1 14.2 44.5 14.5 8.7 26.3 14.2 44.1 24.1 27.5 15.6 14.9 26.8 56.3 23.3 22.6 8.7 26.3 24.2 21.8 51.6 36.6 15.4 32.6 39.2 14.8 18.9 18.2 18.9 11.2 19.6 40.3 44.7 24.0 14.9 88.1 40.8 66.5 33.2 63.5 39.5 44.0 24.1 48.7 17.5 25.4 29.6 28.7 27.7 40.7 19.0 14.0 40.3 36.5 20.0 37.3 16.6 25.6 38.2 26.1 47.0 28.9 23.7 28.3 30.8 5.5 11.7 6.1 24.7 12.6 25.5 19.1 19.9 22.8 13.9 19.3 19.5 19.7 2.9 25.2 10.3 15.7 19.8 17.4 20.8 21.4 20.2 25.6 20.0 20.8 20.6 20.9 19.9 19.4 21.4 21.6 9.3 3.2 10.2 0.0 4.8 0.0 0.0 0.0 0.0 0.0 19.2 12.2 0.0 0.0 8.1 9.2 0.0 34.0 10.8 0.0 11.7 15.7 0.0 6.4 10.2 6.1 0.0 0.0 0.0 17.6 25.2 4.3 0.0 7.7 13.9 32.5 0.0 0.0 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 15.5 0.0 0.0 0.0 0.0 15.7 0.0 0.0 1.8 0.0 0.0 19.3 4.4 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 10.4 5.4 12.1 0.0 0.0 SPP1 "BNSP, BSPI, ETA-1, OPN" ENSG00000118785 "Secreted phosphoprotein 1" P10451 4 87975650-87983426 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Biomineralization, Cell adhesion" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 2424.4;kidney: 3587.6;placenta: 2791.9" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 60702.5" "Group enriched" "Detected in all" 4 "glioma: 1690.9;renal cancer: 1385.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "neutrophil: 24.8" "Lineage enriched" "Detected in single" 249 "granulocytes: 24.8" "Cell line enhanced" "Detected in many" "EFO-21: 4825.8;Hep G2: 2469.7;RPTEC TERT1: 10348.3" "Region enhanced" "Detected in all" "pons and medulla: 316.8" "Low region specificity" "Detected in all" "HPA027540, HPA027541" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 114000000 73000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "HPA027540: AB_10600222, HPA027541: AB_10601446" "unprognostic (4.74e-2)" "prognostic unfavorable (9.52e-4)" "unprognostic (1.13e-3)" "unprognostic (2.04e-1)" "unprognostic (2.31e-2)" "unprognostic (6.96e-3)" "prognostic unfavorable (2.84e-6)" "unprognostic (2.46e-3)" "unprognostic (7.86e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.89e-4)" "unprognostic (4.31e-2)" "unprognostic (2.55e-1)" "unprognostic (7.19e-2)" "unprognostic (1.57e-1)" "unprognostic (3.48e-1)" "unprognostic (2.63e-2)" 113.1 24.4 276.0 59.5 490.3 1.0 70.2 652.0 736.4 27.5 265.0 44.9 9.5 131.2 9.8 4.8 52.8 2424.4 37.0 301.6 417.1 3587.6 35.6 18.8 9.1 813.2 645.3 9.9 292.0 19.2 20.6 2791.9 781.8 15.7 7.6 745.5 88.7 22.1 16.0 2.7 14.4 38.3 472.6 9.2 11.0 11.7 633.1 8.4 8.3 0.4 5.7 25.0 6.0 855.0 2.2 144.0 19.1 1.1 0.0 0.2 0.3 5.6 4.4 1.4 9.1 0.6 0.2 0.2 4825.8 2.3 371.5 1.4 0.0 0.0 3.1 11.2 0.0 0.0 1.8 2469.7 0.3 6.8 5.1 0.5 0.3 34.9 0.1 118.8 4.2 0.2 0.1 10.8 1.3 0.2 1.2 21.3 227.5 0.3 0.0 2.4 0.5 1189.8 10348.3 1.8 1.1 0.9 0.3 0.8 339.1 441.9 0.5 5.2 0.3 11.5 27.1 0.4 25.8 0.9 7.9 13.9 436.3 1.1 457.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 276.0 490.3 652.0 736.4 301.6 417.1 813.2 645.3 781.8 472.6 633.1 855.0 35.7 3.2 4.7 5.2 34.0 1.5 5.2 0.1 1.2 46.6 1767.7 22.4 17.9 1584.2 0.3 2183.1 27.1 335.6 6.9 0.0 1003.7 7273.8 0.1 61.2 25.2 367.9 0.0 2.7 1.4 71.7 294.5 48.9 0.0 154.2 0.0 1.7 5.7 5.0 60702.5 785.7 9.9 0.0 0.0 57.4 7.7 1.0 0.9 247.7 1.8 99.3 69.2 3862.9 0.0 4.5 532.1 215.4 0.0 0.0 0.1 0.4 0.0 5594.0 1.6 169.7 0.0 0.9 21.6 0.5 0.2 1.1 1.0 667.8 30.0 0.4 0.0 9.9 SPP2 SPP24 ENSG00000072080 "Secreted phosphoprotein 2" Q13103 2 234050679-234077134 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4373 "liver: 519.1" "Cell type enriched" "Detected in some" 20 "Hepatocytes: 258.7" "Cancer enriched" "Detected in some" 112 "liver cancer: 65.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 480000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "prognostic favorable (2.33e-6)" "unprognostic (7.02e-3)" "unprognostic (9.62e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 519.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 5.3 0.3 0.6 0.0 0.7 0.0 0.1 5.1 0.0 5.0 258.7 0.1 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 SPRING1 "C12orf49, FLJ21415, LUR1, POST1, SPRING" ENSG00000111412 "SREBF pathway regulator in golgi 1" Q9H741 12 116710171-116738070 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 37.4" "Cell type enhanced" "Detected in some" "Adipocytes: 10.5;Cytotrophoblasts: 11.5;dendritic cells: 9.8;Extravillous trophoblasts: 37.5;Hofbauer cells: 40.9;Syncytiotrophoblasts: 17.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 35.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026905 Uncertain "Intracellular and membrane" NA NA 330000 "Cluster 49: Eosinophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "HPA026905: AB_10603446" "unprognostic (2.74e-3)" "unprognostic (1.41e-1)" "unprognostic (3.66e-2)" "unprognostic (9.19e-2)" "unprognostic (1.30e-1)" "unprognostic (5.76e-2)" "prognostic unfavorable (8.44e-4)" "unprognostic (2.56e-1)" "unprognostic (4.78e-2)" "unprognostic (2.62e-2)" "unprognostic (3.72e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.91e-11)" "unprognostic (3.28e-2)" "unprognostic (2.25e-1)" "unprognostic (8.46e-2)" "unprognostic (1.73e-1)" 5.4 8.2 13.0 7.9 14.8 6.2 5.9 14.3 13.0 3.5 8.5 11.1 6.6 4.3 8.5 7.8 3.4 5.7 7.0 11.5 15.5 15.2 8.7 18.5 8.5 18.2 16.3 3.5 6.8 7.1 6.8 4.4 16.4 4.6 8.4 5.7 13.7 4.2 3.1 6.3 6.4 3.9 13.7 7.2 11.4 9.2 18.4 9.8 37.4 2.4 8.8 5.4 4.1 12.1 12.6 16.7 15.2 15.2 17.4 13.8 19.0 8.6 11.5 9.5 8.2 32.9 9.3 32.3 16.6 11.9 14.1 16.0 21.3 13.2 10.6 26.0 17.1 9.2 8.5 31.6 12.2 17.8 27.3 16.8 16.3 12.4 14.0 16.1 14.5 21.3 10.0 7.3 15.3 18.9 16.2 16.5 24.4 19.2 19.4 24.0 10.3 14.0 24.1 33.7 14.0 17.4 14.0 14.0 25.9 17.1 16.9 18.3 18.9 14.1 19.4 20.0 17.1 15.0 48.7 45.6 22.9 18.2 16.9 3.1 2.4 4.1 4.5 3.3 4.6 5.6 3.5 3.7 2.2 4.9 3.0 4.1 1.7 2.9 2.3 4.3 3.9 1.7 13.0 14.8 14.3 13.0 11.5 15.5 18.2 16.3 16.4 13.7 18.4 12.1 10.5 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 11.5 9.8 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 37.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 17.9 1.6 0.0 0.0 0.0 SPRN "bA108K14.1, FLJ41197, Shadoo" ENSG00000203772 "Shadow of prion protein" Q5BIV9 10 133420666-133424572 "Predicted intracellular proteins, Transporters" Prion "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 13.4;liver: 17.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.5;Hepatocytes: 22.5;Horizontal cells: 3.3;Inhibitory neurons: 5.1;Oligodendrocyte precursor cells: 5.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.66e-1)" "unprognostic (1.64e-3)" "unprognostic (3.38e-3)" "unprognostic (1.95e-1)" "unprognostic (1.35e-1)" "unprognostic (3.31e-2)" "unprognostic (1.07e-1)" "unprognostic (3.90e-3)" "unprognostic (1.68e-1)" "unprognostic (2.07e-1)" "prognostic favorable (1.54e-6)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (1.76e-2)" "unprognostic (1.13e-1)" "unprognostic (7.17e-2)" "prognostic favorable (1.58e-7)" 1.5 4.1 6.2 0.3 8.4 0.0 1.6 5.9 13.4 2.2 0.0 2.4 0.5 1.6 0.0 2.9 1.8 0.2 1.7 7.7 1.4 5.4 17.7 1.7 0.1 0.9 1.9 2.1 3.0 0.2 5.1 0.2 0.2 3.7 0.0 0.6 2.1 0.0 1.9 1.9 3.3 0.3 0.2 4.7 3.6 3.1 2.6 0.0 3.5 0.0 0.0 1.7 2.0 4.3 0.6 0.2 0.4 0.9 0.0 0.0 1.2 1.6 0.0 0.7 0.1 1.2 0.5 1.2 0.3 1.6 0.0 0.9 0.5 0.0 0.0 0.6 1.3 0.3 2.3 0.8 0.2 1.6 0.5 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.6 0.4 0.4 0.8 0.6 1.2 0.5 0.0 0.3 2.2 0.4 0.4 0.0 0.4 0.2 0.8 0.0 0.1 0.8 0.2 0.4 0.3 0.6 0.6 1.1 0.8 0.9 0.8 0.7 1.1 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 8.4 5.9 13.4 7.7 1.4 0.9 1.9 0.2 0.2 2.6 4.3 0.1 0.0 0.0 1.3 0.7 0.0 0.0 0.0 0.0 2.4 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.2 0.7 0.0 0.0 7.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.4 22.5 0.0 3.3 5.1 0.0 0.0 2.1 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.5 0.0 5.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SPRYD3 FLJ14800 ENSG00000167778 "SPRY domain containing 3" Q8NCJ5 12 53064316-53079404 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039426, HPA039685" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane, Actin filaments" "HPA039426: AB_10673358, HPA039685: AB_2676623" "unprognostic (7.73e-3)" "unprognostic (6.55e-2)" "unprognostic (1.37e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (1.27e-3)" "unprognostic (2.58e-1)" "unprognostic (1.83e-2)" "unprognostic (1.43e-2)" "unprognostic (2.64e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.78e-15)" "unprognostic (9.82e-2)" "unprognostic (5.27e-2)" "unprognostic (7.44e-3)" "unprognostic (1.41e-1)" 32.2 29.2 70.6 18.4 77.9 6.4 30.2 35.6 84.2 33.6 38.1 32.8 18.9 38.1 36.2 31.7 45.1 20.4 42.4 79.9 60.4 29.5 22.1 23.6 17.4 61.7 55.1 43.5 50.0 43.3 60.7 14.0 61.5 34.5 17.0 39.3 43.9 40.6 21.2 27.0 23.4 31.6 43.8 24.3 35.8 11.5 58.0 13.7 34.6 23.1 20.6 36.5 30.7 67.9 28.4 43.0 5.6 11.5 45.4 22.4 7.3 42.6 22.2 16.1 10.1 7.4 23.8 18.6 34.2 53.5 19.2 26.0 7.6 32.9 10.5 19.4 11.3 11.5 25.5 16.9 34.0 22.3 20.1 20.2 51.6 23.1 34.9 31.6 33.5 9.3 10.4 45.3 28.5 62.3 16.3 11.7 3.2 23.1 30.8 7.1 9.5 38.4 20.6 22.3 9.4 8.9 37.3 34.6 18.1 3.0 31.8 16.7 46.4 18.1 17.9 40.9 29.0 24.7 24.1 5.4 53.8 19.5 22.4 29.9 16.7 47.5 32.7 28.9 30.9 14.6 22.4 26.9 15.5 11.3 18.8 22.7 25.8 17.0 32.8 7.4 13.5 28.9 70.6 77.9 35.6 84.2 79.9 60.4 61.7 55.1 61.5 43.8 58.0 67.9 13.4 3.2 10.1 4.9 13.3 5.7 19.5 12.0 13.1 46.4 11.3 8.8 20.4 17.2 10.4 18.4 8.4 6.2 8.8 9.1 11.7 30.4 0.9 21.2 10.9 17.1 11.5 2.1 14.4 36.5 14.6 22.9 15.8 16.1 10.1 5.1 18.9 9.1 11.8 43.7 13.5 13.8 10.2 11.7 5.7 2.7 16.1 10.3 10.6 3.7 15.0 38.5 16.5 4.5 5.6 28.6 9.3 33.1 19.1 20.8 10.7 15.6 18.2 23.8 19.7 11.1 20.0 4.5 3.9 12.0 9.5 4.2 14.9 5.1 7.9 16.4 SPX "C12orf39, MGC10946, NPQ, spexin" ENSG00000134548 "Spexin hormone" Q9BT56 12 21526296-21541249 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 111.4" "Group enriched" "Detected in some" 4 "Distal tubular cells: 86.1;Proximal tubular cells: 202.2" "Cancer enriched" "Detected in many" 5 "renal cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 17.5;HBEC3-KT: 8.9;hTERT-HME1: 12.4;SuSa: 14.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebral cortex: 17.1;hippocampal formation: 17.9;olfactory bulb: 7.5;pons: 8.0" "Secreted to blood" NA NA 2650000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.78e-2)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (1.81e-2)" "unprognostic (2.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (5.89e-2)" "unprognostic (1.21e-2)" "unprognostic (1.95e-1)" "prognostic favorable (1.31e-6)" "unprognostic (2.37e-3)" "unprognostic (9.78e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" 111.4 0.1 8.7 0.1 9.2 0.4 4.1 8.6 24.2 0.0 7.2 0.1 0.0 1.3 0.6 0.2 0.2 0.1 2.8 8.1 11.5 26.4 2.3 0.6 0.2 8.6 13.9 0.0 20.7 0.4 0.0 17.7 26.6 0.0 0.0 1.7 6.9 0.5 2.0 0.0 0.3 0.1 8.0 0.4 0.5 0.2 9.6 3.0 20.2 8.8 0.1 0.0 0.0 9.9 0.0 0.5 0.8 0.0 3.0 1.2 0.0 0.0 0.1 0.1 1.2 17.5 0.0 0.7 0.3 0.0 0.3 0.0 0.0 8.9 1.6 0.0 0.0 4.7 0.0 0.1 1.8 0.0 0.0 5.7 0.9 0.3 12.4 0.2 0.0 0.1 0.1 0.0 2.4 0.0 0.0 0.0 1.1 0.0 0.7 0.0 2.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 1.7 14.6 0.0 0.2 0.3 0.0 5.3 0.0 0.4 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.7 9.2 8.6 24.2 8.1 11.5 8.6 13.9 26.6 8.0 9.6 9.9 1.4 0.0 0.0 1.3 1.3 0.0 0.1 0.0 0.0 3.0 0.7 0.9 28.9 0.0 0.0 25.8 0.0 0.0 0.1 0.0 86.1 0.4 0.0 0.5 0.3 0.6 0.0 0.0 0.0 19.1 0.0 1.7 0.0 2.5 0.0 0.0 0.7 0.7 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 13.7 0.0 0.0 1.2 4.9 4.1 0.0 0.1 2.5 0.0 0.0 0.0 0.1 0.0 202.2 0.0 0.5 0.0 2.4 0.9 0.0 1.8 0.0 0.0 0.4 1.0 0.1 0.0 0.1 SQOR "CGI-44, SQR, SQRDL" ENSG00000137767 "Sulfide quinone oxidoreductase" Q9Y6N5 15 45631148-45691281 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 210.0" "Cell type enhanced" "Detected in many" "Ductal cells: 118.1;Exocrine glandular cells: 176.2;Hofbauer cells: 134.3;monocytes: 154.5;Pancreatic endocrine cells: 156.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 304.0" "HPA017079, HPA041589" Enhanced Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA017079: AB_1857467, HPA041589: AB_2677565" "unprognostic (6.15e-2)" "unprognostic (3.28e-2)" "unprognostic (2.15e-1)" "prognostic favorable (2.57e-4)" "unprognostic (2.75e-2)" "unprognostic (5.51e-2)" "unprognostic (6.68e-3)" "prognostic unfavorable (8.80e-4)" "unprognostic (1.81e-1)" "unprognostic (3.77e-1)" "unprognostic (6.65e-3)" "unprognostic (2.37e-1)" "unprognostic (3.14e-3)" "unprognostic (2.29e-1)" "unprognostic (4.92e-2)" "unprognostic (7.44e-2)" "unprognostic (4.38e-1)" 46.4 22.6 14.5 59.5 14.6 55.6 41.2 14.6 19.7 36.3 17.2 210.0 57.7 18.8 19.3 112.9 26.6 31.4 22.0 13.6 14.7 36.6 82.6 61.5 38.2 16.7 15.1 8.8 39.8 24.1 12.5 17.6 15.6 41.2 178.8 4.9 56.3 27.8 132.8 41.7 55.9 43.2 15.9 47.3 54.4 5.1 15.8 23.7 32.5 43.7 57.7 48.8 50.3 17.2 38.3 68.0 0.1 3.9 125.5 151.4 0.4 40.8 132.3 23.6 35.7 2.7 59.0 33.7 38.7 29.9 72.6 33.3 2.0 304.0 13.9 121.7 1.1 3.0 14.5 48.2 38.8 20.2 5.1 45.2 88.2 54.9 119.8 59.4 66.1 32.0 0.4 40.6 24.6 31.3 12.2 44.9 0.0 147.7 41.8 1.4 6.7 47.1 184.9 55.2 1.2 1.2 10.1 25.8 13.1 0.8 56.9 61.7 76.8 9.7 2.2 131.6 9.0 53.5 61.0 2.0 96.9 104.6 10.9 112.5 212.1 84.6 76.6 161.0 104.6 54.3 97.9 83.6 135.2 48.6 51.8 55.2 302.5 53.4 152.4 40.5 149.0 169.6 14.5 14.6 14.6 19.7 13.6 14.7 16.7 15.1 15.6 15.9 15.8 17.2 24.4 32.1 64.1 0.0 5.8 0.0 0.0 0.0 0.0 0.0 31.4 14.7 0.0 0.0 14.9 14.7 0.0 0.7 19.8 0.0 11.7 118.1 0.0 15.9 7.0 13.9 0.0 0.0 0.0 176.2 0.9 11.3 0.0 37.6 11.4 1.3 0.0 0.0 134.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.3 0.0 0.0 154.5 0.0 0.0 0.0 0.0 156.2 0.0 0.0 3.3 0.0 0.0 45.8 24.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.8 13.5 1.6 0.0 0.0 SRCAP "DOMO1, EAF1, KIAA0309, SWR1" ENSG00000080603 "Snf2 related CREBBP activator protein" Q6ZRS2 16 30698209-30741409 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 186.4;Club cells: 145.6;Ionocytes: 179.0;Respiratory ciliated cells: 118.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" HPA028929 Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA028929: AB_10601265" "unprognostic (1.26e-1)" "unprognostic (1.35e-1)" "unprognostic (5.07e-1)" "unprognostic (6.57e-2)" "unprognostic (1.78e-1)" "unprognostic (6.95e-2)" "unprognostic (8.59e-2)" "unprognostic (2.34e-2)" "unprognostic (3.77e-1)" "unprognostic (6.45e-2)" "unprognostic (4.36e-2)" "unprognostic (8.57e-2)" "unprognostic (1.16e-2)" "unprognostic (2.09e-1)" "unprognostic (4.11e-2)" "unprognostic (7.71e-2)" "unprognostic (1.07e-1)" 15.4 11.9 3.6 18.9 4.8 30.1 10.1 7.1 4.2 12.8 1.7 13.2 15.7 15.5 6.4 13.5 14.2 10.9 12.1 2.9 3.4 9.6 7.1 11.6 15.3 5.9 4.3 16.9 19.4 20.2 9.5 12.6 3.5 12.6 11.2 12.5 18.0 13.1 24.5 16.2 16.1 15.0 0.8 18.7 16.0 20.6 7.7 20.2 14.0 19.4 13.6 11.3 9.9 6.8 29.5 60.1 36.9 35.9 28.3 19.5 37.7 24.0 21.1 26.2 20.7 27.8 21.9 65.9 29.7 30.5 16.9 27.8 37.7 27.5 21.9 42.2 88.1 42.5 56.2 24.3 11.4 49.8 48.0 20.8 13.2 40.3 29.0 12.8 27.8 21.7 65.4 36.5 19.7 34.5 42.2 17.4 37.6 10.8 27.7 57.7 28.7 36.4 7.5 34.2 34.5 36.5 26.6 31.0 8.4 12.2 35.4 26.0 44.1 37.0 26.5 21.0 31.6 39.8 36.7 45.9 29.7 23.2 28.9 0.3 0.7 2.9 0.8 1.2 0.6 0.7 0.4 0.9 0.5 1.0 0.5 0.4 2.2 0.6 0.3 0.9 0.9 0.7 3.6 4.8 7.1 4.2 2.9 3.4 5.9 4.3 3.5 0.8 7.7 6.8 3.0 3.2 3.7 8.8 9.8 24.6 1.9 186.4 13.1 7.5 3.3 1.8 2.4 4.3 145.6 1.8 8.4 2.3 5.3 54.3 0.0 1.4 1.2 4.6 3.0 3.4 11.3 7.6 8.6 3.1 1.4 4.2 19.9 4.7 2.5 3.0 2.2 3.0 2.3 8.4 8.6 17.7 179.0 1.9 14.3 0.9 2.8 3.4 10.6 8.4 3.0 1.7 6.2 4.5 10.6 1.9 39.1 1.2 11.1 3.1 3.1 0.6 118.3 5.8 0.0 5.0 14.3 5.6 6.0 7.8 58.2 2.5 8.9 2.0 25.6 3.1 SREK1 "DKFZp564B176, SFRS12, SRrp508, SRrp86" ENSG00000153914 "Splicing regulatory glutamic acid and lysine rich protein 1" Q8WXA9 5 66139971-66183615 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037673, HPA037674, HPA059332" Enhanced Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "HPA037673: AB_2675598, HPA037674: AB_10671376, HPA059332: AB_2683983" "unprognostic (1.38e-1)" "unprognostic (2.51e-1)" "unprognostic (6.16e-2)" "unprognostic (1.52e-1)" "unprognostic (9.40e-2)" "prognostic favorable (2.54e-4)" "unprognostic (1.29e-2)" "unprognostic (7.67e-2)" "unprognostic (5.66e-3)" "unprognostic (2.19e-1)" "unprognostic (2.66e-2)" "unprognostic (5.48e-2)" "prognostic unfavorable (5.77e-4)" "unprognostic (1.63e-1)" "unprognostic (3.08e-1)" "unprognostic (6.76e-2)" "unprognostic (6.69e-2)" 5.6 6.5 6.7 4.4 6.8 20.2 5.9 8.0 8.4 7.4 9.9 6.7 4.5 8.0 5.2 5.4 7.0 4.2 4.9 6.3 7.2 4.8 6.1 6.2 5.9 6.1 6.4 6.4 8.5 6.6 8.1 5.2 6.1 5.4 4.3 9.5 7.0 3.8 4.7 9.0 7.4 3.2 6.0 7.4 6.5 4.8 7.0 5.8 8.0 3.3 4.1 5.5 5.7 7.4 5.5 6.7 8.5 5.5 3.9 7.5 9.5 6.1 3.3 3.1 3.4 9.5 6.3 8.3 7.4 4.5 4.1 7.4 4.3 5.7 5.3 6.0 10.3 7.9 18.0 7.2 3.4 7.0 8.9 4.5 5.6 3.7 4.2 6.4 5.2 4.6 7.4 5.5 3.4 5.6 7.2 16.2 4.8 2.1 3.3 10.2 4.1 6.3 5.6 9.2 10.3 7.3 5.8 2.7 5.1 6.1 7.2 8.7 5.9 5.2 3.3 7.3 6.4 6.0 4.5 8.9 5.1 11.2 5.5 4.9 2.7 2.8 2.4 2.1 2.6 3.2 2.2 2.8 2.3 3.8 2.6 2.6 2.1 3.8 1.9 3.1 2.4 1.5 6.7 6.8 8.0 8.4 6.3 7.2 6.1 6.4 6.1 6.0 7.0 7.4 72.6 93.0 143.5 70.2 67.6 66.0 84.8 69.3 58.6 64.3 64.1 51.4 80.8 60.1 98.8 46.0 116.7 84.6 72.1 59.5 37.2 59.3 46.5 91.2 124.1 83.3 77.8 65.6 71.4 55.4 86.7 80.1 72.4 107.5 97.0 80.5 55.0 68.3 50.2 67.3 73.3 64.2 79.3 54.4 50.2 62.3 83.6 55.4 42.7 40.3 62.3 63.4 53.5 98.0 85.2 54.7 41.8 76.8 70.7 83.7 49.8 32.8 112.2 89.8 46.0 92.3 87.2 78.9 62.0 49.1 69.3 120.7 63.7 85.2 62.5 91.2 SRF MCM1 ENSG00000112658 "Serum response factor" P11831 6 43171269-43181506 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 89.6;Enteroendocrine cells: 102.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001819, CAB005416" Supported Supported Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: OE19 - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Nucleoplasm "CAB005416: AB_2255249, HPA001819: AB_1079928" "unprognostic (1.44e-3)" "unprognostic (1.09e-1)" "unprognostic (5.39e-3)" "unprognostic (2.66e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-2)" "unprognostic (4.60e-2)" "unprognostic (9.84e-2)" "unprognostic (4.28e-2)" "unprognostic (2.21e-2)" "unprognostic (6.72e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.01e-5)" "unprognostic (5.31e-2)" "unprognostic (1.59e-1)" "unprognostic (5.10e-2)" "unprognostic (1.97e-2)" 29.7 16.7 16.0 27.0 15.3 27.3 24.7 12.4 18.7 31.2 12.4 82.6 13.4 69.3 12.4 33.3 49.2 26.5 61.2 17.6 11.6 17.0 20.2 28.6 21.4 14.1 12.7 27.6 21.8 18.5 18.8 17.4 11.8 38.7 14.9 8.8 16.8 45.5 55.4 21.2 29.3 48.2 12.1 22.3 37.0 12.6 13.4 21.4 23.9 32.7 16.5 54.5 25.7 16.7 38.4 15.0 34.2 22.6 19.8 16.2 50.2 34.2 28.0 29.0 17.9 40.4 11.1 48.1 30.5 36.7 36.7 30.4 35.0 30.2 25.5 53.5 34.4 43.6 30.7 40.2 37.7 41.2 50.9 27.8 32.3 44.8 32.7 27.4 24.5 41.0 31.6 36.8 22.2 41.1 51.2 35.9 23.8 85.7 18.3 38.7 34.9 17.3 21.3 24.5 20.0 18.1 28.0 21.1 34.2 26.2 21.7 75.6 29.9 34.2 26.4 33.4 59.5 25.4 22.6 80.6 21.4 29.2 23.5 0.4 0.4 0.8 0.8 0.8 0.6 0.5 0.4 0.6 0.5 0.5 0.3 0.6 1.2 0.3 0.6 1.0 0.6 0.3 16.0 15.3 12.4 18.7 17.6 11.6 14.1 12.7 11.8 12.1 13.4 16.7 17.1 38.5 22.5 3.9 8.8 78.0 64.3 22.6 38.1 5.7 64.0 52.1 89.6 18.6 21.7 11.0 20.9 9.7 9.4 29.8 0.0 13.6 4.7 23.8 24.6 17.5 102.2 20.2 4.9 20.0 22.6 17.0 18.3 29.5 7.6 20.6 17.2 50.6 12.7 10.1 3.5 39.1 8.2 11.3 18.8 1.1 12.5 11.6 24.9 0.0 8.0 12.5 5.2 1.5 2.8 21.5 19.6 29.0 6.5 17.8 11.1 3.8 20.3 7.5 13.1 23.6 21.8 5.2 3.3 28.7 66.9 12.2 10.5 8.9 25.6 30.2 SRGN "PPG, PRG, PRG1" ENSG00000122862 Serglycin P10124 10 69088103-69104805 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Biomineralization" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "bone marrow: 8096.7" "Cell type enhanced" "Detected in many" "dendritic cells: 2922.2;granulocytes: 2343.1;Kupffer cells: 1789.9;Langerhans cells: 6618.2;Macrophages: 3639.1;monocytes: 3188.2;Plasma cells: 1740.9;T-cells: 2235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 5714.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 5714.1" "Cell line enhanced" "Detected in many" "HL-60: 4442.1;NB-4: 2549.7;THP-1: 4346.8;TIME: 2609.1;U-937: 3546.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000759 Enhanced Supported "Golgi apparatus" "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA000759: AB_1079675" "unprognostic (3.61e-2)" "unprognostic (1.62e-2)" "unprognostic (2.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (4.50e-2)" "unprognostic (1.30e-1)" "unprognostic (1.70e-2)" "unprognostic (1.63e-1)" "unprognostic (8.22e-2)" "unprognostic (5.80e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.65e-1)" "unprognostic (2.32e-2)" "unprognostic (4.07e-2)" "unprognostic (4.08e-2)" 404.6 114.9 48.8 799.8 50.5 8096.7 136.4 55.5 99.6 93.2 70.1 101.8 77.9 63.5 25.9 91.0 96.8 316.4 111.9 48.2 67.8 98.3 239.4 347.3 437.2 82.4 59.3 30.7 68.4 131.6 62.1 355.6 67.8 58.9 118.9 15.5 40.1 57.4 37.5 18.9 111.4 219.4 65.5 362.8 95.0 18.3 64.7 228.9 72.7 117.1 314.6 508.3 46.1 71.0 5.3 43.0 0.2 0.4 768.1 749.7 1.2 94.9 63.9 235.1 283.5 0.1 18.2 9.1 117.4 4.1 134.4 1.1 0.0 20.6 799.9 535.7 0.4 87.1 29.8 0.3 312.7 4442.1 914.9 306.8 1.1 641.5 39.2 223.8 1227.8 13.3 82.5 419.9 1239.9 0.2 18.7 2549.7 0.7 0.1 84.6 2.4 2.3 446.7 0.6 6.0 0.3 0.8 2.3 0.6 16.0 0.0 2.2 4346.8 2609.1 187.9 12.9 3.8 20.1 486.4 508.4 57.3 112.2 3546.9 1.2 2349.8 1105.3 2730.6 474.9 774.6 313.4 73.5 228.5 362.8 583.0 39.0 125.5 268.4 5714.1 962.8 693.6 631.9 392.6 1590.5 48.8 50.5 55.5 99.6 48.2 67.8 82.4 59.3 67.8 65.5 64.7 71.0 1081.4 112.2 198.1 0.7 592.0 175.9 12.5 38.3 8.6 1.1 16.0 28.2 21.2 21.5 57.5 33.1 0.0 10.2 2922.2 2.9 0.0 4.2 4.1 4.6 15.0 566.8 1.8 277.8 0.2 9.8 10.2 87.9 70.3 6.6 2343.1 0.4 636.1 22.1 847.1 0.0 0.5 1.7 0.0 1789.9 6618.2 8.4 7.5 3639.1 556.7 80.6 3188.2 1.4 1292.5 0.0 0.2 1.3 1.2 18.0 1740.9 12.2 0.3 4.7 45.6 5.0 72.3 22.8 97.5 0.9 2.2 8.7 141.8 14.2 2235.9 1.2 5.5 18.1 SRL SAR ENSG00000185739 Sarcalumenin Q86TD4 16 4189374-4242080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 41 "heart muscle: 280.1;skeletal muscle: 510.3;tongue: 382.3" "Cell type enriched" "Detected in some" 16 "Cardiomyocytes: 247.3" "Group enriched" "Detected in some" 5 "head and neck cancer: 1.5;thyroid cancer: 5.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "HSkMC: 4.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in some" "basal ganglia: 5.3" "HPA041535, HPA045520" Enhanced "Intracellular and membrane" NA NA 230000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA041535: AB_2677538, HPA045520: AB_2679358" "unprognostic (1.24e-2)" "unprognostic (1.36e-2)" "unprognostic (1.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.21e-1)" "unprognostic (8.11e-2)" "unprognostic (2.04e-7)" "unprognostic (1.41e-1)" "unprognostic (8.28e-2)" "unprognostic (7.40e-4)" "unprognostic (4.91e-2)" "unprognostic (8.70e-2)" "unprognostic (7.78e-4)" "unprognostic (3.33e-2)" "unprognostic (2.15e-1)" "unprognostic (1.51e-3)" "unprognostic (1.68e-4)" 3.0 0.4 1.0 1.2 1.0 0.2 1.7 1.0 1.5 3.2 0.8 1.3 0.4 3.0 2.3 9.6 3.1 1.8 280.1 0.8 1.2 1.4 0.4 1.2 0.7 1.2 1.3 1.3 0.6 0.2 0.5 1.3 1.1 5.6 1.1 8.5 6.4 2.6 510.3 1.1 1.7 3.4 1.0 2.2 1.1 1.0 1.1 1.7 2.3 382.3 1.1 1.4 1.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 1.0 1.0 1.0 1.5 0.8 1.2 1.2 1.3 1.1 1.0 1.1 1.0 0.5 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 1.0 0.0 0.0 247.3 0.0 0.0 1.8 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 0.0 0.0 0.4 0.0 0.0 8.5 0.0 0.1 0.0 0.2 2.9 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.3 0.0 1.8 0.1 0.0 1.0 0.0 1.2 0.0 1.0 0.3 0.1 0.0 3.8 0.0 0.3 0.0 0.2 0.0 12.1 6.6 5.5 15.4 0.1 0.2 0.0 0.4 0.0 0.1 0.4 0.0 0.1 SRP14 "ALURBP, MGC14326" ENSG00000140319 "Signal recognition particle 14" P37108 15 40035690-40039181 "Plasma proteins, Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053738, HPA065118" Approved Nucleoplasm,Nucleoli NA NA 440000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "HPA053738: , HPA065118: " "unprognostic (2.52e-1)" "unprognostic (1.65e-1)" "unprognostic (8.20e-3)" "unprognostic (1.01e-2)" "unprognostic (1.04e-1)" "unprognostic (5.39e-3)" "unprognostic (2.97e-1)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (7.99e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.31e-4)" "unprognostic (2.20e-1)" "unprognostic (8.03e-3)" "unprognostic (1.41e-3)" "unprognostic (4.94e-2)" 309.1 307.5 330.1 118.1 327.1 252.7 300.4 323.8 426.0 301.7 320.4 272.5 121.5 311.2 282.1 257.7 270.7 155.8 390.1 317.9 349.3 391.5 229.5 220.8 168.0 357.0 402.7 323.5 192.4 324.3 306.8 143.8 339.7 264.4 158.9 212.8 237.8 158.9 354.7 201.2 215.7 163.4 321.1 219.7 247.6 165.6 326.2 276.9 275.6 338.5 172.9 266.7 253.9 355.1 131.8 163.7 399.5 301.4 300.0 275.5 189.4 232.4 265.0 213.4 223.3 297.8 113.7 107.9 245.0 305.1 319.5 216.6 322.8 260.9 207.0 257.5 230.3 258.3 530.2 364.0 231.4 238.2 211.8 276.0 298.3 177.8 213.3 391.0 360.6 297.7 280.2 204.2 356.3 204.5 370.2 291.4 217.6 520.1 301.3 247.6 176.8 192.6 477.5 401.7 287.2 255.0 231.2 243.2 171.2 243.7 332.8 448.6 290.9 240.4 160.3 229.4 171.1 161.8 494.7 291.0 234.7 255.4 229.7 729.8 525.0 875.7 484.5 485.8 473.9 600.9 547.9 549.0 562.5 509.0 522.0 510.2 452.7 525.9 459.5 1148.0 755.1 1262.6 330.1 327.1 323.8 426.0 317.9 349.3 357.0 402.7 339.7 321.1 326.2 355.1 1378.8 461.6 415.0 83.2 577.0 667.1 861.7 1395.7 427.4 432.9 617.7 914.5 880.3 649.1 906.9 995.0 125.1 867.3 812.5 742.7 2551.3 1366.9 353.1 1215.7 729.8 957.7 554.0 619.4 39.4 1087.2 1100.4 699.1 324.7 1513.6 564.0 669.5 654.7 819.4 1022.1 348.3 56.1 676.9 1226.8 631.1 882.8 377.3 1039.8 645.8 789.8 36.5 1174.3 1262.8 619.0 39.2 76.0 1240.7 894.4 986.9 610.9 826.3 874.5 2276.2 935.5 477.3 624.5 651.9 749.3 779.9 643.1 631.5 710.3 758.8 644.1 831.9 673.2 975.0 SRPK3 "MSSK1, STK23" ENSG00000184343 "SRSF protein kinase 3" Q9UPE1 X 153776412-153785732 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Myogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 211.4;tongue: 76.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 25.0;Cone photoreceptor cells: 8.4;Oligodendrocytes: 7.4;Skeletal myocytes: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 47.0;U-266/70: 19.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (1.79e-3)" "unprognostic (6.21e-2)" "unprognostic (1.79e-2)" "unprognostic (7.24e-2)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-1)" "unprognostic (4.47e-4)" "unprognostic (2.83e-1)" "unprognostic (1.71e-1)" "unprognostic (4.10e-4)" "unprognostic (8.70e-2)" "unprognostic (5.38e-7)" "unprognostic (1.97e-2)" "unprognostic (1.97e-1)" "unprognostic (3.83e-2)" "unprognostic (1.07e-4)" 1.6 4.3 12.5 2.2 15.8 2.1 1.4 20.2 19.2 3.2 8.7 17.0 3.3 8.4 1.6 6.5 2.9 1.5 47.3 12.2 12.8 1.6 0.7 1.1 2.2 14.6 14.3 2.3 1.6 1.4 18.7 0.5 14.5 7.8 1.7 1.7 7.6 1.1 211.4 5.7 3.9 3.1 11.4 1.9 5.0 1.1 16.0 0.3 0.6 76.8 0.1 6.7 2.7 23.4 5.1 6.7 1.2 3.3 0.0 0.2 1.5 0.6 0.0 0.3 0.1 5.7 0.9 5.1 0.6 0.6 0.5 1.4 0.0 0.1 0.0 4.4 4.6 2.7 5.1 0.9 0.1 1.3 7.6 4.1 0.0 0.0 0.0 0.3 0.0 7.1 3.5 5.8 1.3 10.8 1.0 7.5 1.2 0.3 1.8 2.3 47.0 1.5 0.1 2.3 8.0 3.8 0.0 3.5 1.6 0.5 4.4 5.8 0.1 1.8 4.2 3.5 0.7 19.4 3.5 3.3 1.0 9.5 2.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 12.5 15.8 20.2 19.2 12.2 12.8 14.6 14.3 14.5 11.4 16.0 23.4 0.1 0.0 0.0 3.3 0.0 0.6 1.0 0.1 0.0 4.3 2.5 1.0 25.0 0.0 0.1 0.0 8.4 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.2 0.5 1.2 0.0 0.7 0.0 0.1 1.1 1.5 0.2 0.0 0.2 0.0 0.0 0.0 1.7 1.8 4.0 0.0 0.0 0.2 0.2 0.3 0.1 0.0 0.0 0.1 0.5 0.0 0.5 7.4 0.0 0.0 3.0 0.2 0.7 0.0 0.0 0.1 0.5 0.0 18.9 2.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.6 0.4 SRPRA "SR-alpha, Sralpha, SRP-alpha, SRPR" ENSG00000182934 "SRP receptor subunit alpha" P08240 11 126262938-126269144 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 232.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 19000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.23e-3)" "unprognostic (6.87e-2)" "unprognostic (6.11e-2)" "prognostic favorable (8.56e-4)" "unprognostic (1.44e-2)" "unprognostic (5.21e-2)" "unprognostic (2.87e-1)" "unprognostic (3.64e-1)" "unprognostic (4.78e-1)" "unprognostic (3.96e-2)" "unprognostic (2.22e-2)" "unprognostic (2.73e-1)" "unprognostic (3.72e-1)" "unprognostic (1.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.93e-1)" "unprognostic (2.74e-2)" 64.4 78.9 24.9 71.4 25.9 82.5 58.0 27.2 32.5 85.6 51.7 54.7 53.1 64.8 144.2 55.7 57.4 64.7 62.9 26.7 29.2 54.1 164.0 65.5 67.4 28.9 26.9 55.8 254.8 71.5 88.9 49.9 28.9 81.8 61.9 36.3 236.8 87.7 91.1 53.8 52.2 68.8 25.6 66.7 96.3 32.7 30.6 61.8 90.2 69.3 86.4 82.0 48.6 27.6 65.5 63.5 59.5 90.9 160.1 124.0 79.5 183.8 168.5 87.4 102.9 117.5 163.4 122.2 186.4 182.3 109.2 126.4 91.1 105.8 87.2 134.9 71.9 223.8 49.1 117.9 223.7 198.7 139.9 106.4 132.5 134.6 245.0 105.5 120.9 47.7 76.2 284.3 124.1 87.6 95.9 78.5 39.7 193.1 135.5 62.8 82.3 128.4 86.8 132.2 85.5 80.3 125.6 150.9 95.7 48.0 198.7 117.5 115.5 153.2 68.2 88.0 132.8 123.3 85.0 73.9 85.3 177.5 202.5 72.1 61.8 95.9 91.3 67.4 79.7 48.7 62.6 74.0 59.4 41.1 56.3 65.2 64.3 62.3 82.8 78.1 53.5 94.7 24.9 25.9 27.2 32.5 26.7 29.2 28.9 26.9 28.9 25.6 30.6 27.6 52.9 44.8 69.3 0.0 69.1 0.0 53.5 0.0 44.9 30.4 37.6 24.9 0.0 32.9 46.4 22.0 8.4 38.0 81.7 12.1 1.9 64.3 9.8 33.5 53.2 36.5 12.2 24.6 0.0 90.9 42.4 42.9 35.2 67.9 49.2 25.9 32.9 77.9 25.7 60.6 0.0 14.2 0.0 27.0 0.0 8.4 36.4 43.4 0.0 0.0 56.6 28.0 52.5 0.0 0.0 67.6 9.5 46.6 232.5 60.6 25.1 19.2 21.1 28.8 46.0 42.3 30.7 18.5 34.3 36.3 0.0 81.0 64.3 38.4 9.5 66.3 SRPX ETX1 ENSG00000101955 "Sushi repeat containing protein X-linked" P78539 X 38149336-38220924 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 215.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 256.9;Granulosa cells: 138.9;Hepatic stellate cells: 418.7;Leydig cells: 110.3;Peritubular cells: 95.2" "Group enriched" "Detected in all" 5 "glioma: 64.2;melanoma: 70.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 49 "plasmacytoid DC: 7.8" "Lineage enriched" "Detected in single" 49 "dendritic cells: 7.8" "Cell line enhanced" "Detected in many" "ASC diff: 3742.4;ASC TERT1: 827.3;HSkMC: 1258.3;HUVEC TERT2: 803.2" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "spinal cord: 12.4" "Secreted - unknown location" NA NA 140000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.35e-1)" "unprognostic (1.09e-3)" "unprognostic (1.08e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (6.48e-2)" "unprognostic (3.83e-3)" "unprognostic (3.50e-2)" "unprognostic (2.31e-1)" "unprognostic (4.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.30e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (7.80e-13)" "unprognostic (6.94e-3)" "unprognostic (3.90e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.36e-4)" 215.2 37.2 8.2 22.4 12.8 0.1 148.0 17.8 5.9 48.6 5.2 83.0 7.9 56.1 39.6 36.6 113.4 58.1 93.3 7.0 16.7 7.4 17.7 46.6 5.0 13.2 14.2 21.4 23.9 2.7 4.6 88.9 15.4 18.3 24.8 1.6 22.9 15.3 15.6 29.2 52.6 52.9 15.1 1.7 42.5 6.7 13.8 19.2 59.1 13.6 5.3 103.8 42.9 15.4 0.3 5.0 12.1 0.2 3742.4 827.3 0.9 35.3 67.8 11.9 20.2 0.5 3.6 0.1 0.3 74.3 119.9 1.9 2.0 30.8 9.8 0.2 13.8 0.1 1.0 0.4 167.8 3.0 0.4 1258.3 2.6 114.9 58.3 132.8 803.2 1.4 0.1 0.2 130.1 1.7 0.5 0.1 10.2 1.8 26.2 0.0 43.5 6.4 0.8 2.3 2.3 2.3 1.7 0.1 170.1 31.2 0.0 0.4 349.1 82.2 42.3 108.8 103.7 0.0 0.1 0.1 239.0 3.1 106.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 0.0 0.1 8.2 12.8 17.8 5.9 7.0 16.7 13.2 14.2 15.4 15.1 13.8 15.4 28.7 3.2 1.3 17.0 0.6 15.3 2.2 2.8 7.4 0.4 2.9 8.6 14.2 0.0 0.2 1.8 0.0 3.6 2.1 2.5 0.0 0.3 0.7 1.1 35.1 67.2 0.0 2.7 1.9 0.4 5.4 256.9 1.5 0.8 0.0 138.9 418.7 2.5 6.1 0.0 2.7 5.8 0.0 11.4 15.2 4.9 110.3 1.6 74.7 1.0 0.0 0.2 0.0 2.5 0.3 0.8 1.8 95.2 0.2 1.6 0.4 0.2 0.0 0.4 26.3 4.8 54.6 0.7 2.3 1.7 7.2 7.1 1.9 21.4 0.5 0.8 SRPX2 SRPUL ENSG00000102359 "Sushi repeat containing protein X-linked 2" O60687 X 100644195-100675788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.8" "Cell type enhanced" "Detected in many" "Adipocytes: 20.9;Fibroblasts: 34.3;Granulosa cells: 21.6;Microglial cells: 37.5;Skeletal myocytes: 17.5;Urothelial cells: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 282.3;ASC TERT1: 116.9;HSkMC: 103.3;HUVEC TERT2: 72.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 2.8" HPA038786 Approved "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA038786: AB_10672724" "unprognostic (4.10e-2)" "unprognostic (4.55e-2)" "unprognostic (2.08e-1)" "unprognostic (3.72e-2)" "unprognostic (1.96e-1)" "unprognostic (4.21e-3)" "unprognostic (3.59e-3)" "unprognostic (5.41e-2)" "unprognostic (3.22e-2)" "unprognostic (1.26e-1)" "unprognostic (2.86e-2)" "unprognostic (2.29e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.84e-3)" "unprognostic (1.69e-1)" "unprognostic (8.67e-2)" "unprognostic (3.85e-1)" 31.8 7.5 3.6 6.3 4.5 0.2 20.7 1.3 2.6 11.3 8.5 7.1 1.2 6.0 0.9 17.7 7.1 3.1 12.7 2.8 5.8 13.9 5.4 13.8 0.4 4.3 5.6 8.3 2.9 0.7 2.5 9.3 3.1 6.3 1.8 0.1 4.6 3.8 3.4 3.7 5.1 4.4 2.0 12.9 4.5 1.1 7.4 0.3 4.3 4.8 1.2 16.8 10.9 2.5 11.7 1.2 2.9 0.1 282.3 116.9 0.0 26.3 19.8 8.0 25.1 1.4 17.6 0.0 1.1 15.9 7.5 0.7 0.2 13.1 8.6 0.1 0.1 0.2 0.9 2.8 29.3 0.2 0.6 103.3 0.3 27.8 0.9 24.6 72.7 0.0 0.0 0.1 27.1 0.0 0.0 0.0 3.4 0.2 0.3 0.0 2.5 0.0 11.4 37.6 0.4 0.0 0.0 0.8 0.2 6.1 0.3 0.1 36.7 13.8 12.3 10.3 0.9 0.1 0.0 0.1 18.3 0.0 8.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.5 1.3 2.6 2.8 5.8 4.3 5.6 3.1 2.0 7.4 2.5 20.9 0.0 0.6 10.1 0.3 0.4 5.0 6.5 0.6 0.0 4.8 1.8 0.9 0.0 13.7 0.0 0.0 0.2 0.0 1.9 0.0 1.6 3.6 0.6 11.2 1.6 0.0 0.0 0.4 0.0 0.4 34.3 1.1 0.4 0.0 21.6 4.6 0.2 0.9 0.0 0.2 0.1 4.1 0.3 1.6 2.7 15.8 0.3 0.0 37.5 0.0 0.0 0.0 2.0 0.1 0.8 0.0 6.0 0.2 1.6 0.0 0.1 15.5 0.0 0.0 17.5 14.6 0.2 0.1 0.6 0.4 0.5 0.3 2.6 0.4 49.1 SSBP4 ENSG00000130511 "Single stranded DNA binding protein 4" Q9BWG4 19 18418864-18434562 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071780 Approved Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA071780: " "unprognostic (2.81e-2)" "unprognostic (8.47e-3)" "unprognostic (4.94e-1)" "unprognostic (1.14e-1)" "unprognostic (1.52e-1)" "unprognostic (2.44e-2)" "unprognostic (3.38e-2)" "unprognostic (1.56e-2)" "unprognostic (3.67e-1)" "unprognostic (7.85e-2)" "prognostic favorable (1.01e-4)" "unprognostic (3.32e-2)" "prognostic unfavorable (2.04e-10)" "unprognostic (4.50e-2)" "unprognostic (1.97e-1)" "unprognostic (4.26e-2)" "unprognostic (1.05e-2)" 52.2 42.7 74.2 18.0 87.1 14.0 44.3 32.9 97.5 87.0 88.3 51.1 17.0 72.7 5.5 28.8 101.2 6.9 51.5 78.6 56.4 75.9 31.8 50.7 12.6 44.4 46.0 69.0 38.0 6.7 129.6 12.2 31.5 57.7 4.3 5.3 27.4 21.8 41.2 24.1 43.7 6.8 38.0 79.7 38.3 41.2 68.1 6.9 45.7 8.1 4.3 48.0 48.6 40.9 37.4 32.3 27.4 53.5 5.1 20.0 38.0 51.7 11.4 11.7 12.9 12.4 41.9 33.5 45.7 11.6 13.0 42.8 7.1 9.8 4.8 35.9 80.4 59.2 37.9 28.4 20.6 27.9 106.7 16.2 7.9 7.5 2.8 16.0 38.2 66.0 120.0 16.5 3.8 60.0 74.2 91.5 22.2 19.1 84.8 49.8 22.2 35.6 17.5 12.6 49.2 82.3 8.2 26.7 75.4 5.3 27.0 64.5 45.0 19.7 51.7 121.5 31.4 23.0 7.0 23.1 53.3 85.9 42.9 0.0 5.6 0.3 12.0 14.9 7.9 14.5 9.8 10.4 7.4 11.1 5.8 10.0 0.7 5.1 26.2 4.4 5.6 4.5 74.2 87.1 32.9 97.5 78.6 56.4 44.4 46.0 31.5 38.0 68.1 40.9 54.1 6.4 18.6 21.2 43.5 17.2 35.3 23.5 26.7 11.8 39.4 36.8 6.1 18.6 21.2 53.3 25.0 20.6 83.6 13.7 25.4 13.8 10.5 99.0 69.0 53.4 59.9 24.4 43.4 21.1 44.8 51.7 27.5 31.2 37.4 49.4 37.1 12.1 34.8 42.1 29.0 17.3 34.6 41.5 38.4 29.6 58.4 39.0 19.6 16.9 23.4 41.3 70.0 10.1 6.3 12.8 12.9 51.6 19.5 36.4 6.6 19.8 96.7 16.2 39.5 23.6 48.7 20.0 58.9 17.2 14.6 18.9 79.0 80.4 21.6 34.3 SSC4D "S4D-SRCRB, SRCRB-S4D, SRCRB4D" ENSG00000146700 "Scavenger receptor cysteine rich family member with 4 domains" Q8WTU2 7 76389334-76409697 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.6;parathyroid gland: 7.0" "Cell type enhanced" "Detected in some" "Collecting duct cells: 11.0;Distal tubular cells: 3.9;Hepatocytes: 3.7;Spermatogonia: 3.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "EFO-21: 6.7;Hep G2: 9.6;SuSa: 10.7;U-2 OS: 25.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA062611 Uncertain "Secreted - unknown location" NA NA 980000 "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 9: U-2 OS - Unknown function" "Cluster 7: Non-specific - Mitochondria" "HPA062611: AB_2684807" "unprognostic (3.39e-2)" "unprognostic (1.78e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (2.83e-6)" "prognostic unfavorable (7.08e-4)" "unprognostic (3.52e-2)" "unprognostic (3.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.49e-2)" "unprognostic (8.49e-3)" "unprognostic (3.18e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (4.71e-4)" "unprognostic (2.59e-1)" "unprognostic (3.90e-1)" "unprognostic (2.56e-2)" "unprognostic (1.73e-2)" 0.7 0.3 0.2 0.0 0.4 0.0 0.3 0.0 0.2 0.3 0.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 2.6 0.4 0.1 0.0 0.2 0.2 0.7 2.2 7.0 2.6 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.1 0.0 0.5 0.0 0.0 1.0 0.0 0.3 0.0 0.8 0.2 0.0 0.0 0.1 1.0 0.5 0.0 0.0 10.7 0.2 0.0 0.0 0.0 25.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.2 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.5 1.6 0.1 0.0 0.5 0.0 0.6 0.4 1.4 1.4 2.1 0.0 0.0 11.0 0.0 0.3 0.0 0.2 3.9 1.9 0.1 0.5 0.1 0.3 0.0 0.0 1.6 1.7 1.4 0.4 0.0 0.4 0.0 0.7 1.1 3.7 2.8 1.7 1.4 0.1 0.0 0.6 0.0 0.4 0.9 0.9 0.0 0.0 0.0 2.4 0.0 0.0 0.8 0.4 0.1 0.4 0.0 0.4 0.4 1.3 0.0 0.2 0.0 0.8 0.6 0.6 3.5 1.0 0.0 0.3 0.1 0.6 0.2 0.4 SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 19.3;Fibroblasts: 27.0;Leydig cells: 18.0;Peritubular cells: 15.8;Skeletal myocytes: 32.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 26.9;BJ: 22.7;fHDF/TERT166: 27.5;hTERT-RPE1: 23.2;U-87 MG: 27.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Yes NA 88000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA042008: AB_10804124, HPA053316: " "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.28e-2)" "unprognostic (4.55e-2)" "unprognostic (6.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (4.26e-8)" "unprognostic (7.73e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-2)" "unprognostic (2.21e-3)" 13.1 2.2 2.6 3.6 4.6 0.1 8.8 3.0 2.1 23.0 1.8 33.6 1.9 39.7 3.9 5.7 17.0 12.9 17.6 1.8 2.1 3.6 1.7 9.1 1.3 3.9 2.6 14.5 1.8 0.3 17.6 1.9 4.0 8.8 2.8 1.1 3.4 12.8 3.6 5.6 8.7 20.1 2.2 11.1 9.8 2.6 3.6 2.0 3.8 2.8 0.5 10.6 15.9 2.1 0.1 1.4 0.5 0.0 3.3 26.9 0.0 22.7 5.5 3.7 4.6 0.4 0.0 1.2 0.3 27.5 1.1 0.0 0.0 0.0 1.9 0.1 0.3 5.6 1.5 0.0 5.2 0.1 9.6 12.3 0.0 5.4 0.0 23.2 0.0 0.7 0.2 0.3 0.6 0.1 0.1 0.5 0.9 0.0 0.2 0.7 1.2 0.3 2.5 0.0 2.9 0.4 0.4 0.0 0.5 0.5 0.4 1.2 7.9 1.0 1.3 1.1 3.8 0.4 0.0 0.1 27.8 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.6 3.0 2.1 1.8 2.1 3.9 2.6 4.0 2.2 3.6 2.1 3.5 3.2 0.6 4.2 0.3 1.9 0.3 0.3 0.0 5.3 0.8 1.1 2.8 0.0 0.1 0.0 2.1 0.1 0.4 0.8 1.9 0.1 0.6 1.5 19.3 3.3 0.0 0.0 1.5 0.0 0.1 27.0 2.0 0.9 0.0 0.5 2.2 0.0 1.2 3.3 1.1 0.4 0.0 1.0 3.8 1.3 18.0 2.0 1.8 2.8 0.7 2.1 0.0 0.0 0.3 0.1 0.3 15.8 0.3 0.3 4.6 0.2 0.7 1.9 0.0 32.1 6.8 0.9 1.1 0.4 1.8 0.0 0.5 0.9 1.4 0.2 SSH1 "KIAA1298, SSH1L" ENSG00000084112 "Slingshot protein phosphatase 1" Q8WYL5 12 108778191-108857590 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "WM-115: 63.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019845 Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA019845: AB_1857497" "unprognostic (1.18e-3)" "unprognostic (3.00e-1)" "unprognostic (2.49e-1)" "unprognostic (2.70e-2)" "unprognostic (9.40e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (5.80e-5)" "unprognostic (3.28e-2)" "unprognostic (3.69e-2)" "unprognostic (1.72e-3)" "unprognostic (7.12e-2)" "unprognostic (3.42e-1)" "unprognostic (1.71e-2)" "unprognostic (1.41e-1)" "unprognostic (8.66e-2)" "unprognostic (9.55e-2)" "unprognostic (6.22e-2)" 6.6 5.1 5.6 5.1 5.1 7.9 5.0 9.2 5.5 5.8 7.2 7.2 2.9 5.9 4.0 5.5 5.3 5.3 7.8 5.7 5.3 6.7 5.5 11.8 4.1 5.8 5.7 5.0 4.3 5.4 5.2 5.2 5.2 5.2 4.1 5.7 3.9 4.8 11.9 4.6 5.1 5.5 5.0 7.5 4.9 3.5 5.1 3.6 5.3 6.5 4.2 6.0 5.2 5.1 9.9 12.7 8.2 6.4 15.1 12.8 7.2 12.8 26.1 11.0 9.7 6.4 4.6 4.9 8.7 29.0 18.8 9.8 4.9 20.7 8.9 9.9 4.8 11.3 6.0 4.0 8.1 5.8 28.4 17.7 7.0 10.0 22.0 27.1 10.3 5.6 2.5 3.6 29.1 5.4 6.6 8.0 5.8 3.8 10.3 4.6 9.8 6.1 4.5 17.1 6.1 8.1 11.0 2.8 24.2 11.2 3.9 4.8 8.1 19.6 8.4 11.9 7.1 7.3 7.0 5.6 10.3 4.5 63.1 1.8 0.9 2.0 1.0 1.5 0.9 0.6 0.5 0.9 0.6 0.6 0.4 0.5 2.1 0.7 1.2 0.7 0.6 0.5 5.6 5.1 9.2 5.5 5.7 5.3 5.8 5.7 5.2 5.0 5.1 5.1 34.5 9.6 16.1 26.1 6.3 9.4 20.8 23.6 19.4 12.9 6.9 6.6 25.1 11.5 12.7 14.7 16.7 6.0 18.5 8.2 5.9 8.4 2.2 10.8 17.1 52.2 5.4 7.8 27.3 8.2 4.4 14.0 13.7 16.9 20.8 12.0 29.3 15.2 12.3 11.8 35.4 5.4 0.0 23.0 20.3 5.0 6.5 21.1 12.4 55.3 33.7 7.8 14.4 14.1 14.8 12.3 2.4 12.8 13.1 21.8 4.0 6.7 9.0 19.1 6.6 17.8 18.1 1.4 7.7 13.2 8.9 2.3 17.9 7.6 7.8 13.9 SSH2 KIAA1725 ENSG00000141298 "Slingshot protein phosphatase 2" Q76I76 17 29625938-29930276 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.5" "Cell type enhanced" "Detected in all" "Excitatory neurons: 269.0;Inhibitory neurons: 255.2;Microglial cells: 254.8;Oligodendrocytes: 547.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 134.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017189, HPA057099" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "CAB017189: , HPA057099: AB_2683336" "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (3.00e-3)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "unprognostic (9.80e-3)" "unprognostic (7.52e-2)" "unprognostic (1.48e-2)" "unprognostic (8.28e-2)" "unprognostic (7.70e-2)" "unprognostic (2.74e-1)" "unprognostic (1.86e-1)" 15.6 9.5 11.7 22.5 13.1 62.8 10.7 12.8 16.3 7.1 3.6 13.0 8.3 7.3 8.9 12.7 8.2 8.9 19.4 13.1 23.2 15.1 13.6 21.4 29.0 19.0 14.4 3.9 14.6 6.2 7.1 10.4 18.5 6.3 10.9 8.1 10.7 4.5 91.5 14.4 20.7 7.9 11.4 28.3 15.5 28.2 16.3 28.9 13.9 35.6 24.8 9.0 8.7 24.5 25.8 19.0 12.6 10.8 36.1 24.7 8.8 12.3 12.9 19.6 19.2 12.9 9.0 22.1 18.8 14.1 12.6 31.0 14.8 17.1 22.4 7.1 28.1 14.9 21.2 17.4 16.6 16.7 30.7 30.4 12.3 20.6 13.4 9.7 47.3 36.2 9.9 16.8 13.7 7.3 74.9 15.5 9.4 9.3 11.5 37.9 31.9 37.0 35.7 20.3 20.6 32.3 18.0 18.6 36.6 16.3 12.6 19.4 25.6 12.6 26.3 23.5 16.1 26.9 20.0 53.8 16.4 13.1 12.3 47.2 15.2 134.8 10.4 20.2 8.5 21.3 11.6 11.1 12.7 22.4 11.5 8.7 91.6 4.6 36.7 7.7 16.4 6.5 11.7 13.1 12.8 16.3 13.1 23.2 19.0 14.4 18.5 11.4 16.3 24.5 19.6 9.6 38.5 81.6 137.0 39.6 12.3 20.6 27.9 12.4 22.2 19.2 28.2 12.8 23.2 16.5 27.1 20.4 68.7 54.3 25.4 14.9 108.4 27.9 10.1 26.9 35.4 27.8 269.0 35.5 26.4 22.2 33.1 32.5 12.6 6.0 19.6 26.9 22.3 20.2 255.2 34.8 14.2 120.2 31.3 174.4 12.2 75.9 35.6 254.8 83.6 9.2 82.4 184.0 547.9 40.3 38.6 8.2 49.4 12.9 64.5 63.1 18.4 22.9 6.6 34.4 17.0 80.9 16.7 37.6 36.2 18.2 65.8 14.2 21.6 30.2 SSH3 "FLJ10928, FLJ20515" ENSG00000172830 "Slingshot protein phosphatase 3" Q8TE77 11 67303478-67312607 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.6;eosinophil: 11.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.6" "Cell line enhanced" "Detected in many" "HaCaT: 64.9;MCF7: 64.1;RT4: 111.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019949, HPA019957" Approved Approved "Nuclear speckles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear speckles, Cytosol" "Plasma membrane, Actin filaments" "HPA019949: AB_1857498, HPA019957: AB_1857499" "unprognostic (4.38e-2)" "unprognostic (1.37e-1)" "unprognostic (3.50e-3)" "unprognostic (3.73e-2)" "unprognostic (2.61e-3)" "unprognostic (9.30e-2)" "unprognostic (2.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.89e-4)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (6.78e-3)" 14.4 7.8 8.9 4.0 12.0 9.3 16.2 14.1 11.6 25.9 9.5 19.3 13.3 16.0 7.5 41.9 18.3 11.5 12.5 9.1 10.1 13.1 10.9 12.7 3.1 14.6 10.8 23.5 15.3 9.8 9.7 6.5 13.2 29.9 9.3 1.2 26.2 28.8 6.8 25.2 15.0 6.1 12.3 9.4 20.1 2.3 11.5 1.9 16.3 3.8 4.8 37.4 32.5 14.9 17.3 18.7 0.4 0.6 11.4 11.8 18.8 10.3 13.7 5.6 5.1 21.2 46.8 1.0 32.5 10.5 11.9 64.9 6.0 46.4 2.8 3.6 6.3 4.3 32.2 9.9 8.2 0.9 16.0 12.2 40.5 8.3 8.3 12.9 6.3 0.4 0.1 1.5 6.2 64.1 0.8 7.3 4.2 48.9 13.8 20.6 0.6 3.1 18.2 111.2 3.7 5.8 24.8 41.0 12.8 6.3 57.1 15.3 10.4 4.5 9.8 12.7 2.7 1.5 0.9 0.5 12.7 6.9 4.9 11.6 1.5 11.1 2.0 2.3 1.7 0.2 1.9 1.7 1.7 0.1 0.8 0.8 4.4 1.5 1.1 1.1 1.8 1.1 8.9 12.0 14.1 11.6 9.1 10.1 14.6 10.8 13.2 12.3 11.5 14.9 7.6 3.2 8.7 8.5 0.9 7.0 20.8 25.2 11.4 0.8 21.3 17.3 3.8 20.0 23.4 16.5 0.0 15.1 3.3 28.3 3.9 19.4 0.1 8.3 5.6 4.7 3.6 5.2 4.2 21.6 24.9 8.0 20.9 17.8 3.8 8.1 3.9 5.0 7.7 1.7 5.3 14.4 24.4 6.2 3.1 0.6 13.1 4.8 8.8 2.8 9.2 4.8 7.2 0.0 15.9 20.0 21.0 12.0 0.7 15.4 20.2 7.4 11.6 0.5 0.0 4.9 9.2 0.5 0.4 27.0 10.4 15.7 4.4 5.3 21.4 26.8 SSR2 "TLAP, TRAPB" ENSG00000163479 "Signal sequence receptor subunit 2" P43308 1 156009048-156020951 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 62000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.93e-1)" "unprognostic (3.86e-2)" "unprognostic (9.85e-2)" "unprognostic (2.77e-1)" "unprognostic (2.05e-1)" "unprognostic (4.84e-2)" "prognostic unfavorable (2.86e-4)" "unprognostic (7.35e-2)" "unprognostic (4.55e-2)" "unprognostic (2.04e-3)" "unprognostic (1.05e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (1.00e-7)" "unprognostic (1.28e-1)" "unprognostic (4.64e-1)" "unprognostic (4.55e-2)" "unprognostic (1.30e-1)" 190.4 290.6 104.4 157.0 108.5 245.8 276.7 105.1 119.2 281.4 111.8 187.6 140.8 201.4 457.4 134.6 184.3 180.0 128.7 102.2 108.1 165.4 233.1 192.5 220.1 104.4 104.6 325.7 513.1 168.0 136.6 194.1 104.6 158.2 246.3 55.7 293.5 155.4 92.3 163.8 158.7 208.2 105.0 206.5 217.3 108.1 107.5 230.1 152.8 105.5 277.4 222.1 153.9 107.1 249.4 197.1 330.9 576.6 531.9 593.1 239.0 384.6 664.6 514.5 526.3 231.8 418.9 219.7 348.8 733.2 195.9 274.0 230.8 302.2 494.9 206.0 234.7 150.0 207.0 296.4 409.3 394.5 275.2 474.1 372.4 369.6 514.0 468.2 670.1 245.6 145.8 611.3 525.8 368.9 200.7 303.7 462.0 590.8 298.0 170.2 204.7 751.5 344.0 189.5 256.3 640.6 275.8 630.1 432.5 373.1 391.0 732.4 324.4 219.8 216.5 210.2 377.2 753.1 390.4 267.4 304.9 317.5 374.0 674.9 403.3 326.5 408.0 301.4 471.0 385.6 436.2 422.1 344.8 327.5 442.1 390.1 336.4 412.8 282.5 404.0 393.8 1070.9 104.4 108.5 105.1 119.2 102.2 108.1 104.4 104.6 104.6 105.0 107.5 107.1 187.3 169.9 151.3 10.1 324.0 241.9 222.9 453.4 140.0 43.2 296.0 368.4 41.1 235.9 243.5 119.5 33.3 435.5 340.7 178.6 140.8 497.9 56.4 95.7 298.6 189.1 229.4 117.1 10.8 571.6 761.6 272.3 154.9 186.5 187.1 292.1 192.4 132.2 349.8 18.5 13.6 392.7 233.9 258.1 348.4 79.6 284.3 223.0 298.8 15.0 315.8 125.2 385.2 10.1 14.7 410.7 273.0 212.1 520.7 221.9 292.9 255.7 76.7 46.0 164.3 167.6 244.3 268.6 81.7 140.1 238.0 570.3 333.2 268.1 292.9 259.5 SST SMST ENSG00000157005 Somatostatin P61278 3 187668912-187670394 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 449.5;intestine: 386.6;pancreas: 479.4;stomach 1: 418.0" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 1404.1;Intestinal goblet cells: 460.2" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 1039.3" "Region enhanced" "Detected in all" "hypothalamus: 449.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 22.4;U-2 OS: 44.7;U-251 MG: 7.6;U-698: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000075, HPA019472, CAB034105" Enhanced Supported "Secreted to blood" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB000075: AB_2688022, CAB034105: AB_2271061, HPA019472: AB_1857360" "unprognostic (2.44e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.12e-3)" "unprognostic (1.54e-2)" "unprognostic (4.69e-1)" "unprognostic (3.31e-2)" "unprognostic (8.16e-3)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (8.47e-2)" "unprognostic (4.19e-1)" "unprognostic (3.27e-1)" "unprognostic (1.45e-1)" 5.5 43.0 59.9 4.6 52.1 4.2 0.5 1.3 67.8 0.6 2.5 31.8 386.6 0.7 0.1 1.6 0.4 1.1 1.3 30.6 449.5 6.2 0.3 0.3 1.5 96.9 48.1 2.4 479.4 0.0 9.3 0.1 50.3 1.3 23.8 6.3 0.1 21.6 0.1 8.9 133.3 2.8 137.8 0.2 418.0 0.2 117.2 1.1 1.0 0.0 0.0 7.3 1.8 18.7 0.0 0.0 0.8 0.1 0.0 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.5 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 44.7 0.4 7.6 0.0 2.9 11.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.9 52.1 1.3 67.8 30.6 449.5 96.9 48.1 50.3 137.8 117.2 18.7 0.0 0.0 0.0 9.1 0.5 0.0 0.0 3.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 5.5 0.0 0.1 0.0 4.3 0.0 0.0 0.3 0.3 0.5 0.1 1404.1 0.0 1.7 0.0 0.2 0.7 0.0 4.2 0.0 0.0 0.0 0.0 0.3 0.0 146.2 460.2 215.7 0.0 0.0 0.1 0.0 0.0 0.0 9.4 3.6 0.0 0.0 3.0 9.1 0.0 0.6 0.0 0.0 0.0 11.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.9 13.8 0.2 SSUH2 "C3orf32, fls485, ssu-2" ENSG00000125046 "Ssu-2 homolog" Q9Y2M2 3 8619400-8745040 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 2.5;intestine: 3.7;testis: 3.9" "Group enriched" "Detected in some" 4 "Early spermatids: 61.7;Late spermatids: 43.6;Proximal enterocytes: 16.1" "Cancer enhanced" "Detected in some" "testis cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 27 "Hep G2: 26.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA049777 Approved NA NA "Cluster 45: Intestine - Brush border" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 29: Early spermatids - Spermatogenesis" "HPA049777: AB_2680876" "unprognostic (2.49e-1)" "unprognostic (7.62e-2)" "unprognostic (9.65e-2)" "unprognostic (1.68e-1)" "unprognostic (2.46e-1)" "unprognostic (8.86e-2)" "unprognostic (1.46e-3)" "unprognostic (9.79e-2)" "unprognostic (1.53e-1)" "unprognostic (4.09e-1)" "unprognostic (7.97e-3)" "unprognostic (1.52e-1)" "unprognostic (3.15e-3)" "unprognostic (1.31e-1)" "unprognostic (3.65e-2)" "unprognostic (4.96e-2)" "unprognostic (7.50e-2)" 0.5 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.2 0.0 0.5 3.7 0.2 0.0 0.2 0.2 0.4 2.5 0.0 0.0 0.9 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.1 0.1 3.3 0.1 0.0 1.6 0.3 3.9 0.0 0.0 0.8 0.1 0.1 0.2 0.2 0.1 0.0 0.5 0.6 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 9.9 0.0 0.0 1.3 0.0 0.3 0.1 0.1 0.0 0.0 0.3 0.8 1.8 0.0 0.1 0.0 0.0 0.0 0.1 3.1 0.0 0.0 61.7 1.7 0.1 3.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.2 0.0 0.7 2.2 0.0 0.0 0.0 1.9 1.8 0.0 0.0 0.4 43.6 1.2 0.2 1.8 1.0 0.0 0.0 0.0 2.0 1.4 0.1 1.2 0.4 0.0 0.1 16.1 0.9 4.0 0.0 0.0 0.4 0.7 0.5 1.1 0.3 0.1 0.0 0.1 0.5 0.8 0.2 ST3GAL1 "SIAT4A, SIATFL, ST3GalA.1, ST3O" ENSG00000008513 "ST3 beta-galactoside alpha-2,3-sialyltransferase 1" Q11201 8 133454848-133571940 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 75.9;PC-3: 131.8;RT4: 102.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040466 Approved "Intracellular and membrane" NA NA 860000 "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "HPA040466: AB_10805712" "unprognostic (1.36e-2)" "unprognostic (1.11e-2)" "unprognostic (6.66e-2)" "unprognostic (1.83e-3)" "unprognostic (5.53e-3)" "unprognostic (4.43e-2)" "unprognostic (4.79e-2)" "unprognostic (2.66e-1)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (3.55e-3)" "unprognostic (1.10e-1)" "unprognostic (1.83e-3)" "unprognostic (1.67e-2)" "unprognostic (3.29e-2)" "unprognostic (8.64e-3)" "unprognostic (2.95e-2)" 25.7 22.5 8.8 22.8 8.6 22.6 12.2 5.3 9.4 11.4 12.3 6.5 3.6 11.6 12.7 14.0 15.5 19.0 53.1 9.6 6.3 44.5 67.7 19.2 23.1 7.9 11.2 13.3 15.4 10.9 9.9 13.8 6.9 8.0 5.5 10.0 24.9 10.2 43.8 5.9 9.9 10.6 7.2 21.2 16.1 4.3 7.4 17.4 66.1 49.3 21.6 34.4 10.9 7.2 14.0 6.6 3.0 8.3 28.6 15.0 14.4 15.4 35.5 5.7 4.4 13.3 15.1 3.3 10.3 28.2 2.7 4.2 9.4 11.3 4.9 37.6 1.7 28.4 22.5 25.4 22.0 5.9 22.1 17.8 5.7 19.5 11.7 27.2 26.4 7.5 0.5 42.5 4.4 14.9 8.4 8.0 2.1 75.9 131.8 9.9 3.7 24.3 2.7 102.2 0.7 2.0 6.8 23.3 6.9 15.4 4.3 8.1 26.3 18.3 28.5 15.7 6.9 53.0 39.3 3.6 41.7 19.8 18.5 47.8 8.8 41.7 24.1 8.1 22.9 22.7 25.2 28.3 5.3 38.6 34.4 32.4 16.1 43.2 20.4 12.6 17.2 18.9 8.8 8.6 5.3 9.4 9.6 6.3 7.9 11.2 6.9 7.2 7.4 7.2 29.4 6.4 56.8 38.2 68.4 5.7 14.4 14.8 21.1 13.4 13.7 8.4 63.2 12.8 22.2 1.8 2.1 9.7 65.5 4.6 5.9 41.3 3.4 8.9 29.2 44.3 0.0 38.5 36.7 25.4 53.5 47.8 10.7 28.1 8.8 12.1 37.9 159.8 37.8 60.6 34.6 0.6 16.2 52.5 29.0 2.1 36.7 48.8 14.2 49.6 59.8 11.5 47.4 5.0 2.4 39.4 0.0 71.8 29.1 10.9 0.0 48.5 6.5 23.3 13.1 28.1 23.6 0.2 2.8 30.0 3.4 26.4 79.9 6.5 0.3 43.6 ST3GAL4 "CGS23, FLJ11867, NANTA3, SAT3, SIAT4, SIAT4C, STZ" ENSG00000110080 "ST3 beta-galactoside alpha-2,3-sialyltransferase 4" Q11206 11 126355640-126440344 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 270.0;Paneth cells: 214.3;Syncytiotrophoblasts: 962.5" "Cancer enhanced" "Detected in all" "melanoma: 57.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 111.9;neutrophil: 71.8;plasmacytoid DC: 93.7" "Group enriched" "Detected in many" 12 "dendritic cells: 93.7;granulocytes: 111.9" "Cell line enhanced" "Detected in all" "SK-MEL-30: 234.7;WM-115: 515.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049827 Approved "Intracellular and membrane" NA NA 15000 "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA049827: AB_2680900" "unprognostic (8.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.92e-2)" "unprognostic (6.93e-2)" "unprognostic (8.33e-2)" "unprognostic (3.80e-2)" "unprognostic (2.71e-3)" "unprognostic (1.90e-3)" "unprognostic (2.62e-1)" "unprognostic (1.80e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (3.16e-3)" "unprognostic (2.79e-2)" "unprognostic (1.28e-1)" "unprognostic (8.36e-3)" "unprognostic (8.78e-3)" 23.4 117.1 25.2 14.4 41.2 19.0 19.5 43.5 28.9 29.2 36.5 58.1 4.2 16.3 87.6 70.7 19.2 23.9 60.0 24.3 28.7 41.0 28.4 38.2 10.0 42.3 41.3 111.3 13.7 1.7 15.7 35.3 39.5 22.6 66.4 10.8 44.2 16.0 6.1 16.7 12.3 19.0 31.9 41.5 13.3 42.2 37.6 6.3 14.7 7.7 22.7 49.3 33.8 57.2 26.4 21.4 17.0 13.6 46.8 39.4 38.5 30.2 56.6 26.5 18.2 11.4 44.5 7.0 21.9 47.0 88.0 37.1 34.0 19.2 20.0 27.7 9.7 62.8 52.7 13.4 29.9 78.8 126.1 31.5 30.7 39.9 60.9 47.7 34.6 27.5 41.4 18.8 32.2 107.3 25.7 76.5 10.2 166.2 136.6 25.8 50.3 3.3 6.0 74.1 29.5 18.4 32.8 193.5 234.7 10.6 66.3 52.2 13.2 61.7 14.2 44.1 56.2 2.0 4.3 4.0 28.5 118.7 515.8 111.9 5.3 0.7 5.2 8.7 4.8 0.4 1.7 3.3 20.6 0.1 0.6 2.6 71.8 4.7 3.8 93.7 0.3 6.4 25.2 41.2 43.5 28.9 24.3 28.7 42.3 41.3 39.5 31.9 37.6 57.2 10.3 9.6 0.6 17.0 1.9 10.6 6.6 23.0 0.6 4.0 12.8 6.7 25.9 5.7 23.1 31.3 10.4 115.9 37.5 149.2 49.0 6.1 1.5 3.2 9.8 15.0 5.3 3.4 16.3 6.6 72.3 43.2 2.0 10.2 41.9 270.0 31.8 11.9 17.8 5.0 17.5 115.7 16.2 5.9 14.9 7.2 76.1 11.2 78.2 3.7 9.5 5.4 18.6 5.0 83.3 5.3 214.3 93.6 6.7 16.5 0.0 3.9 5.5 10.0 13.1 4.3 43.1 1.5 17.4 0.7 6.7 962.5 8.4 36.8 23.2 41.1 ST6GAL1 SIAT1 ENSG00000073849 "ST6 beta-galactoside alpha-2,6-sialyltransferase 1" P15907 3 186930325-187078553 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 495.9;lymphoid tissue: 148.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 237.3;Hepatic stellate cells: 258.5;Hepatocytes: 608.7;Microglial cells: 602.4" "Cancer enhanced" "Detected in all" "liver cancer: 70.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 250.6;U-266/70: 628.0;U-266/84: 887.9;U-698: 334.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015018, CAB016122" Supported "Secreted to blood" NA NA 15000000 3300000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB015018: AB_629203, CAB016122: AB_627178" "unprognostic (5.85e-3)" "unprognostic (4.19e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (2.64e-1)" "unprognostic (2.44e-2)" "unprognostic (1.38e-3)" "unprognostic (3.43e-2)" "unprognostic (3.17e-1)" "unprognostic (2.20e-1)" "unprognostic (3.99e-1)" "unprognostic (1.43e-1)" "unprognostic (1.91e-2)" "unprognostic (7.30e-3)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "unprognostic (1.93e-2)" 24.5 12.5 27.0 50.2 26.2 15.2 32.5 29.8 24.8 61.4 33.3 38.1 13.9 16.1 5.9 13.5 27.0 17.8 36.0 25.8 33.9 60.0 495.9 30.1 101.7 44.0 37.5 10.1 8.1 45.5 9.8 18.5 50.3 48.8 45.4 2.6 39.3 14.6 12.8 8.3 29.1 18.9 44.1 67.5 28.8 3.5 39.2 66.6 64.8 20.2 148.1 28.0 8.9 48.3 4.3 5.0 20.6 17.1 1.1 0.0 36.3 1.6 3.0 1.4 2.0 1.9 2.0 250.6 19.5 0.1 8.8 10.1 132.7 15.4 1.6 11.3 7.4 10.1 0.8 119.0 1.3 22.8 75.0 1.7 28.3 0.0 11.5 19.9 77.5 24.2 52.2 20.3 5.2 8.7 17.0 14.7 49.9 11.3 7.6 38.2 0.4 8.1 9.9 0.5 36.4 4.1 1.5 26.6 64.6 29.1 38.9 16.8 32.6 0.2 3.3 0.6 2.1 628.0 887.9 334.0 0.5 45.4 84.7 22.6 8.9 3.6 46.9 16.2 42.9 87.9 51.3 39.7 14.2 83.3 80.4 58.4 4.2 26.9 29.3 11.9 43.8 58.7 27.0 26.2 29.8 24.8 25.8 33.9 44.0 37.5 50.3 44.1 39.2 48.3 34.6 44.8 27.4 13.4 110.0 4.0 13.8 68.0 4.6 0.3 5.1 4.1 26.2 75.8 55.9 237.3 0.0 0.3 26.3 20.7 0.0 17.1 0.5 8.9 5.0 56.0 94.1 24.8 47.2 0.9 3.5 3.7 7.7 16.1 10.8 7.3 258.5 608.7 20.3 0.0 31.5 10.9 34.6 61.3 16.4 1.1 0.3 18.2 7.2 602.4 17.2 0.1 26.8 145.3 2.8 6.0 17.8 0.7 124.3 103.6 0.6 0.5 39.8 1.1 0.0 2.2 6.8 0.0 0.5 0.8 1.6 0.7 28.4 0.3 37.3 39.0 ST6GAL2 "KIAA1877, SIAT2, St6GalII" ENSG00000144057 "ST6 beta-galactoside alpha-2,6-sialyltransferase 2" Q96JF0 2 106801600-106887108 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.0;thyroid gland: 28.7" "Group enriched" "Detected in some" 4 "Astrocytes: 58.8;Excitatory neurons: 78.7;Granulosa cells: 111.5;Inhibitory neurons: 44.8;Oligodendrocyte precursor cells: 94.0" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 16.0" "Group enriched" "Detected in many" 77 "amygdala: 6.9;basal ganglia: 7.4;cerebral cortex: 11.0;hippocampal formation: 10.8;thalamus: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.3;hTERT-RPE1: 6.4;NTERA-2: 4.4;PC-3: 5.9;RPMI-8226: 9.6;SCLC-21H: 6.1;U-138 MG: 7.5;U-266/70: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014459 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli fibrillar center" Nucleoplasm "HPA014459: AB_1857528" "unprognostic (2.08e-1)" "unprognostic (5.80e-2)" "unprognostic (1.55e-1)" "unprognostic (4.63e-2)" "unprognostic (6.44e-3)" "unprognostic (1.62e-1)" "unprognostic (2.35e-2)" "unprognostic (1.10e-2)" "unprognostic (1.29e-4)" "unprognostic (4.56e-3)" "unprognostic (7.04e-2)" "unprognostic (1.84e-2)" "unprognostic (7.01e-4)" "unprognostic (4.70e-4)" "unprognostic (4.06e-2)" "unprognostic (2.83e-1)" "unprognostic (2.07e-2)" 0.5 0.1 6.9 0.2 7.4 1.0 0.7 0.0 11.0 1.7 0.0 1.1 0.2 2.6 0.3 1.8 0.7 5.1 0.5 10.8 0.0 0.4 2.6 0.6 0.3 0.0 0.0 0.6 0.1 0.1 0.1 1.5 0.0 0.8 2.3 1.9 0.8 0.8 0.1 0.7 0.4 2.0 0.0 0.1 0.6 5.3 4.6 0.1 28.7 0.0 0.3 0.6 1.0 0.1 0.0 5.3 2.8 0.0 0.0 0.0 0.1 0.2 0.0 1.2 0.3 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.9 0.0 6.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 4.4 0.0 5.9 0.0 0.0 9.6 0.2 0.0 6.1 3.9 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.5 0.1 0.2 0.0 9.9 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 6.9 7.4 0.0 11.0 10.8 0.0 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 58.8 0.0 0.9 0.2 0.0 18.8 6.6 0.2 3.4 1.4 0.0 0.6 1.8 0.0 0.0 0.0 4.7 0.0 0.1 0.4 0.8 12.2 0.3 1.2 6.3 78.7 0.0 0.0 1.7 0.0 0.5 0.0 111.5 2.2 0.0 0.2 0.0 44.8 3.3 0.0 0.0 0.0 1.2 0.3 0.1 0.0 2.8 0.0 0.9 0.0 94.0 1.9 0.0 1.0 0.7 0.0 0.3 0.0 0.6 0.0 0.5 0.0 0.2 2.9 0.1 1.1 4.3 0.0 0.3 0.1 0.1 3.2 0.0 ST6GALNAC2 "SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM" ENSG00000070731 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2" Q9UJ37 17 76565377-76586956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 10 "Early spermatids: 501.1;Late spermatids: 1763.3" "Cancer enhanced" "Detected in all" "melanoma: 22.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "neutrophil: 47.0" "Lineage enriched" "Detected in many" 16 "granulocytes: 47.0" "Cell line enhanced" "Detected in some" "BEWO: 25.4;HaCaT: 33.8;HBEC3-KT: 28.5;hTCEpi: 73.1;MCF7: 36.4;SK-MEL-30: 112.5;T-47d: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (8.93e-3)" "unprognostic (5.86e-3)" "unprognostic (1.67e-2)" "unprognostic (5.18e-3)" "unprognostic (3.37e-2)" "unprognostic (3.79e-2)" "unprognostic (8.79e-2)" "unprognostic (1.95e-1)" "unprognostic (5.37e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (6.48e-4)" "unprognostic (1.57e-1)" "unprognostic (5.17e-3)" "unprognostic (3.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" 5.6 2.9 1.0 1.9 1.1 1.0 12.2 1.2 1.4 14.9 33.0 13.8 1.0 4.8 10.3 16.4 50.5 1.9 4.5 2.0 1.6 9.6 1.2 17.5 0.6 5.4 6.7 1.2 6.3 7.5 2.1 6.0 4.1 11.1 6.0 52.8 11.3 10.2 18.3 51.6 4.8 2.3 4.2 3.7 7.1 33.9 2.6 1.5 25.2 18.5 4.8 9.5 14.5 2.7 2.6 0.0 0.0 0.0 0.5 0.0 25.4 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.5 1.7 0.1 33.8 0.3 28.5 0.0 0.0 0.0 0.0 1.2 0.0 1.2 0.0 0.0 0.0 73.1 0.1 9.0 3.8 0.1 0.0 0.0 0.0 0.4 36.4 0.0 0.0 0.0 0.9 1.0 0.0 0.0 0.0 0.0 9.8 0.5 0.0 4.1 0.1 112.5 1.3 23.4 0.7 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 2.9 5.2 0.0 1.8 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 47.0 0.2 0.4 0.0 0.0 0.4 1.0 1.1 1.2 1.4 2.0 1.6 5.4 6.7 4.1 4.2 2.6 2.7 0.2 0.0 1.5 2.6 0.8 32.9 44.0 104.2 23.9 7.9 0.4 1.5 5.1 7.2 21.0 0.0 27.1 12.5 0.0 2.4 0.0 0.3 501.1 4.5 1.1 3.9 0.0 0.0 0.5 0.0 21.1 2.0 4.6 0.6 1.3 0.0 7.9 1.5 3.0 0.0 1.3 4.8 8.2 5.0 6.9 1763.3 7.5 3.8 65.8 1.0 2.7 84.9 0.0 0.0 0.2 0.1 0.5 7.2 0.2 15.2 0.7 0.5 39.3 79.7 19.7 7.3 3.4 7.6 4.6 28.8 30.3 10.5 2.2 0.0 1.6 37.6 ST6GALNAC5 "MGC3184, SIAT7E, ST6GalNAcV" ENSG00000117069 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5" Q9BVH7 1 76867480-77067546 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 480.3;Inhibitory neurons: 417.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.9" "Region enhanced" "Detected in many" "cerebral cortex: 5.9;hippocampal formation: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.7;fHDF/TERT166: 5.4;HaCaT: 2.7;SH-SY5Y: 4.1;U-2 OS: 4.4;U-251 MG: 2.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 51.3" "HPA065593, HPA070354" Uncertain Approved Vesicles "Intracellular and membrane" NA Yes 180000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA065593: AB_2685515, HPA070354: AB_2686260" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (1.72e-1)" "unprognostic (1.49e-2)" "unprognostic (2.82e-2)" "unprognostic (2.04e-2)" "unprognostic (4.67e-2)" "unprognostic (2.72e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-1)" "unprognostic (1.61e-2)" "unprognostic (1.58e-1)" "unprognostic (2.10e-2)" "unprognostic (5.90e-3)" "unprognostic (9.66e-2)" "unprognostic (6.88e-2)" "unprognostic (1.69e-2)" 0.1 3.0 1.5 1.5 1.1 0.0 1.2 0.0 5.9 0.7 0.0 1.8 0.2 0.1 0.0 1.0 1.9 2.2 0.5 5.5 0.0 0.1 0.0 3.6 0.4 0.0 0.0 1.6 0.1 0.0 1.9 0.1 0.0 1.0 0.6 3.2 0.5 0.3 0.0 0.2 0.9 3.0 0.0 0.2 1.5 0.3 0.0 0.0 0.0 0.0 0.3 1.6 0.6 0.0 1.2 0.0 4.7 0.0 0.0 0.0 0.0 0.4 1.5 1.1 0.4 0.0 0.1 0.0 0.0 5.4 0.0 2.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.3 0.4 0.0 0.0 1.1 4.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 4.4 0.0 2.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 5.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.5 0.5 35.6 0.1 0.0 0.0 0.1 0.0 20.7 2.8 1.7 1.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.2 1.9 0.4 0.0 0.0 480.3 0.0 0.1 0.8 0.0 0.2 1.3 0.9 0.0 0.0 0.1 0.0 417.3 0.2 0.0 0.0 0.0 2.3 0.6 0.1 0.0 8.4 0.0 0.7 0.0 10.6 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 1.3 0.0 0.2 0.4 0.1 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.1 ST6GALNAC6 "SIAT7F, ST6GALNACVI" ENSG00000160408 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6" Q969X2 9 127885321-127905408 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 258.8;Intestinal goblet cells: 100.6;Paneth cells: 178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "NK-cells: 23.7;T-cells: 25.6" "Cell line enhanced" "Detected in all" "ASC diff: 157.1" "Low region specificity" "Detected in all" HPA018890 Approved "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA018890: AB_1857531" "unprognostic (2.27e-1)" "unprognostic (5.23e-2)" "unprognostic (2.81e-1)" "unprognostic (4.54e-2)" "unprognostic (1.81e-2)" "unprognostic (5.71e-2)" "unprognostic (1.36e-1)" "unprognostic (4.84e-2)" "unprognostic (6.05e-2)" "unprognostic (1.40e-3)" "unprognostic (3.24e-3)" "unprognostic (3.31e-2)" "unprognostic (3.29e-1)" "unprognostic (1.10e-2)" "unprognostic (9.85e-2)" "unprognostic (3.46e-2)" "unprognostic (2.67e-2)" 95.8 37.4 155.5 21.4 156.0 17.7 68.7 129.5 177.8 48.7 120.2 75.5 9.5 48.6 50.0 35.0 67.2 28.4 61.3 165.6 130.9 50.1 63.5 66.7 27.5 133.4 137.2 83.0 52.8 32.4 26.0 22.0 128.3 40.2 126.4 16.0 28.3 41.5 46.0 37.4 35.2 38.0 128.3 64.1 43.9 17.6 140.6 14.9 32.5 40.2 23.1 56.6 42.6 134.6 12.0 9.2 18.9 36.9 157.1 91.9 7.4 29.7 69.6 43.7 35.9 16.3 10.0 13.8 13.4 68.1 28.4 21.9 25.6 23.7 19.0 50.9 14.0 13.4 19.0 16.7 48.1 3.3 18.9 94.9 27.5 34.0 15.1 61.6 40.9 11.9 12.2 14.6 54.9 9.9 8.4 19.3 9.1 12.3 17.5 24.6 27.0 14.3 32.2 2.4 13.1 21.3 21.4 8.8 7.6 12.3 9.3 29.0 26.7 27.6 16.3 30.5 15.8 18.4 9.8 21.5 24.5 4.1 8.7 3.3 1.2 0.1 25.3 1.9 18.5 5.3 16.5 18.8 1.8 3.9 10.0 13.7 0.6 23.7 5.0 2.1 25.6 12.4 155.5 156.0 129.5 177.8 165.6 130.9 133.4 137.2 128.3 128.3 140.6 134.6 1.3 3.2 4.3 13.1 10.5 23.2 17.2 15.7 9.1 22.0 0.9 0.6 8.7 8.6 9.5 0.0 6.2 4.3 11.7 258.8 0.0 0.3 2.5 0.8 1.7 20.6 38.5 26.1 11.5 0.4 7.7 26.6 3.6 1.4 7.0 0.2 46.8 28.5 11.6 25.2 10.7 100.6 18.3 10.0 35.6 9.4 66.5 4.1 24.9 8.4 3.2 58.7 46.4 5.5 3.8 0.3 178.3 60.9 8.9 20.5 0.3 0.0 16.1 8.5 85.5 41.2 31.9 1.4 4.8 10.3 26.9 3.6 17.7 0.5 84.7 18.6 ST7 "ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7" ENSG00000004866 "Suppression of tumorigenicity 7" Q9NRC1 7 116953238-117230176 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 184.1;Early spermatids: 131.4;Excitatory neurons: 191.5;Inhibitory neurons: 176.0;Oligodendrocyte precursor cells: 111.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 115.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038325, HPA038326" Approved Supported Nucleoplasm,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm Cytosol "HPA038325: AB_10671740, HPA038326: AB_10672644" "unprognostic (3.40e-2)" "unprognostic (1.04e-1)" "unprognostic (1.33e-1)" "unprognostic (4.70e-2)" "unprognostic (1.09e-1)" "unprognostic (8.18e-2)" "unprognostic (3.32e-2)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (4.45e-3)" "unprognostic (1.46e-1)" "unprognostic (2.48e-2)" "prognostic favorable (3.39e-5)" "unprognostic (1.80e-1)" "unprognostic (1.96e-1)" "unprognostic (8.41e-2)" "unprognostic (3.40e-2)" 13.5 21.7 22.6 6.7 22.0 17.8 15.2 50.6 24.7 19.9 11.1 13.6 12.1 14.5 35.8 9.7 18.6 12.3 22.4 21.8 22.6 29.4 41.3 26.1 7.6 15.0 17.4 17.4 32.9 19.0 24.5 20.9 15.9 13.8 12.4 12.6 21.7 21.2 12.5 11.5 11.0 12.6 14.6 10.4 17.3 8.7 22.5 8.6 28.4 11.2 8.6 12.6 11.1 19.7 29.4 17.2 28.2 24.4 31.0 20.5 12.3 23.0 30.2 24.4 35.2 24.0 32.8 7.7 25.5 21.4 34.7 24.6 24.2 24.5 31.3 11.1 33.9 23.4 26.5 20.2 21.8 27.4 39.4 16.1 24.3 30.7 21.8 21.6 24.9 5.2 36.0 54.6 22.3 18.1 0.2 21.0 26.9 40.1 19.3 6.7 18.8 33.6 25.5 16.2 42.2 33.8 27.8 115.5 32.0 20.6 10.1 23.3 19.1 27.6 11.0 30.5 23.3 34.7 28.2 29.6 22.9 24.0 28.6 1.5 3.1 0.4 7.3 1.2 5.1 2.2 4.4 6.2 5.7 1.0 2.9 3.0 0.0 7.0 1.1 5.6 10.3 3.0 22.6 22.0 50.6 24.7 21.8 22.6 15.0 17.4 15.9 14.6 22.5 19.7 6.3 22.4 38.1 184.1 5.0 7.5 8.6 8.8 10.8 12.2 9.0 7.4 13.5 12.8 12.9 5.5 0.0 21.1 6.4 3.1 5.9 6.0 131.4 7.1 5.9 9.5 3.6 15.8 191.5 13.4 22.8 10.6 12.8 14.2 19.6 3.5 8.6 24.5 8.7 3.3 176.0 6.8 8.2 14.4 6.0 53.5 11.1 7.9 7.2 44.0 7.5 12.8 4.1 111.1 46.9 8.8 3.6 6.0 10.3 6.7 3.6 17.3 6.3 1.3 0.0 9.9 12.1 12.8 5.8 7.4 5.5 21.2 4.6 4.6 5.3 8.8 ST8SIA4 "PST, PST1, SIAT8D" ENSG00000113532 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4" Q92187 5 100806933-100903282 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.0" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 73.3;Kupffer cells: 92.4;Langerhans cells: 149.3;Microglial cells: 101.2;monocytes: 97.5;Plasma cells: 73.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 91.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 41.1;HDLM-2: 69.3;Karpas-707: 57.2;NB-4: 27.9;RPMI-8226: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA051126, HPA053995" Approved Approved "Golgi apparatus" "Intracellular and membrane" NA NA 980000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA051126: AB_2681352, HPA053995: AB_2682336" "unprognostic (2.25e-1)" "unprognostic (2.04e-2)" "unprognostic (1.04e-1)" "unprognostic (1.98e-2)" "unprognostic (1.14e-1)" "unprognostic (6.45e-3)" "unprognostic (1.91e-1)" "unprognostic (5.46e-2)" "unprognostic (2.87e-1)" "unprognostic (1.49e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.80e-7)" "unprognostic (6.07e-2)" "unprognostic (4.38e-2)" "unprognostic (1.30e-1)" "unprognostic (1.23e-2)" 5.8 1.9 2.2 14.0 2.4 7.6 2.2 1.6 2.4 1.9 2.5 3.3 3.2 1.6 0.5 1.1 1.8 5.0 2.3 1.8 4.5 0.7 2.6 5.7 12.3 4.8 3.6 0.5 0.8 1.0 0.6 11.1 5.2 1.3 4.2 0.6 1.2 0.8 0.8 0.8 4.5 2.8 2.7 11.8 3.0 0.4 4.3 9.5 2.0 1.7 10.3 5.5 1.1 4.5 0.0 6.1 41.1 0.0 2.6 3.9 1.0 0.0 0.0 0.0 0.3 0.0 0.0 3.3 0.1 0.0 1.0 0.1 1.0 0.1 0.1 69.3 0.0 2.5 0.4 0.0 0.0 13.0 5.0 3.2 0.0 0.1 0.1 5.3 7.7 10.1 0.0 57.2 2.4 0.6 18.6 27.9 0.3 0.0 0.3 10.3 0.7 44.8 0.2 0.0 0.9 0.0 0.0 0.0 0.1 0.2 0.0 11.6 2.7 0.4 0.2 0.0 0.6 18.6 20.3 3.9 1.0 15.8 5.1 58.0 18.5 22.9 13.1 21.7 9.9 11.1 8.7 11.1 12.2 9.9 5.4 10.1 91.7 10.6 24.0 3.7 17.4 12.2 2.2 2.4 1.6 2.4 1.8 4.5 4.8 3.6 5.2 2.7 4.3 4.5 35.8 6.4 14.1 1.6 49.7 8.3 0.4 2.1 2.2 0.6 0.9 0.9 2.3 1.5 10.1 0.0 0.0 9.4 44.0 0.0 1.9 0.2 0.2 0.9 1.6 28.4 0.0 8.2 6.8 0.0 42.4 5.0 1.1 0.3 24.1 0.1 7.1 0.1 22.6 0.0 73.3 0.2 4.1 92.4 149.3 0.7 0.0 57.5 14.2 101.2 97.5 3.2 34.0 4.5 1.6 0.0 0.0 0.4 73.8 0.2 0.0 0.3 16.6 0.9 13.1 1.2 3.7 0.5 0.8 0.4 5.5 19.2 37.7 0.7 0.0 0.5 ST8SIA6 SIAT8F ENSG00000148488 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6" P61647 10 17315421-17454595 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.5;lung: 5.9" "Cell type enriched" "Detected in some" 5 "Microglial cells: 137.7" "Cancer enhanced" "Detected in some" "breast cancer: 5.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "HMC-1: 208.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011635, HPA072708" Uncertain Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA011635: AB_2194921, HPA072708: " "unprognostic (4.86e-3)" "unprognostic (7.01e-2)" "unprognostic (5.85e-3)" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.11e-2)" "unprognostic (6.81e-2)" "unprognostic (2.32e-1)" "unprognostic (3.23e-2)" "unprognostic (7.53e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-2)" "unprognostic (3.26e-4)" "unprognostic (2.43e-1)" "unprognostic (2.22e-1)" "unprognostic (1.07e-3)" 0.7 0.3 5.8 0.4 4.1 1.8 5.2 3.2 3.6 0.3 2.4 0.6 0.3 0.4 4.6 0.5 0.3 0.5 3.4 2.9 3.3 0.8 1.0 5.9 0.2 5.4 10.5 0.4 0.2 0.0 0.3 1.1 4.6 1.5 0.4 0.4 0.6 0.2 0.2 1.0 0.4 0.3 3.6 0.6 0.3 0.3 8.0 0.3 0.4 0.8 0.4 0.2 0.4 4.3 0.2 0.2 0.1 1.7 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.6 0.6 0.0 0.1 0.3 0.3 0.5 0.1 0.0 0.0 0.4 0.2 25.9 0.4 0.5 0.0 0.0 208.0 0.1 0.0 0.2 0.1 1.8 0.0 0.3 4.6 0.4 2.5 1.9 1.1 0.4 2.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 9.3 0.2 1.1 0.0 3.6 0.1 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.4 0.1 1.7 0.5 0.5 0.5 0.1 0.2 0.1 0.3 0.3 0.2 0.3 0.3 0.4 1.0 0.7 0.3 0.2 0.8 0.2 5.8 4.1 3.2 3.6 2.9 3.3 5.4 10.5 4.6 3.6 8.0 4.3 0.6 0.0 0.0 2.6 0.1 0.6 0.1 0.2 0.0 0.0 10.0 3.9 0.8 0.0 0.2 0.0 0.0 0.0 5.5 1.2 0.0 0.0 0.5 0.1 0.0 10.9 0.0 25.5 3.0 0.0 0.0 0.3 0.0 0.8 10.2 2.8 26.7 0.0 0.1 0.0 4.4 0.0 0.0 0.9 0.0 0.6 0.0 0.2 8.8 137.7 0.2 0.0 8.2 1.5 1.1 0.1 0.1 0.0 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.8 0.3 0.0 0.0 0.0 2.4 0.1 0.0 0.1 STAG1 "SA-1, SA1, SCC3A" ENSG00000118007 "Stromal antigen 1" Q8WVM7 3 136336236-136752403 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 166.8;Microglial cells: 231.4;Oligodendrocyte precursor cells: 223.2;Oligodendrocytes: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035015, HPA058653" Supported Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA035015: AB_10603117, HPA058653: AB_2683787" "unprognostic (1.82e-1)" "unprognostic (1.11e-2)" "unprognostic (1.41e-1)" "unprognostic (5.37e-2)" "unprognostic (4.05e-2)" "unprognostic (1.92e-1)" "unprognostic (4.62e-2)" "unprognostic (5.26e-2)" "unprognostic (1.74e-1)" "unprognostic (7.22e-3)" "unprognostic (1.29e-2)" "unprognostic (1.71e-1)" "unprognostic (5.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.58e-1)" "unprognostic (5.97e-2)" "unprognostic (2.83e-2)" 13.7 9.1 7.6 12.3 8.8 15.7 15.6 17.0 8.3 16.9 9.9 13.5 9.6 19.3 10.6 10.8 13.5 10.3 10.5 6.5 8.7 12.0 10.8 11.2 14.7 9.3 7.8 21.9 12.4 13.7 5.0 17.6 9.0 10.8 14.4 13.2 11.6 12.1 15.0 13.7 11.0 16.1 8.8 11.8 10.0 8.9 7.8 22.5 15.8 15.8 15.9 12.0 11.5 11.2 34.6 17.6 29.1 25.1 21.5 36.8 15.7 37.9 48.4 35.0 33.0 30.2 14.9 26.9 23.3 39.7 28.1 23.4 31.6 17.3 47.4 33.2 14.9 28.8 25.1 16.7 16.3 50.6 27.7 23.4 19.3 25.6 28.6 20.3 27.5 28.8 18.7 52.7 22.3 29.5 33.6 16.4 19.0 23.7 13.9 29.6 31.6 35.7 19.1 24.5 14.2 22.8 40.8 16.0 17.5 15.0 22.9 21.2 23.3 40.1 29.0 36.0 33.9 39.1 28.9 59.5 24.6 17.0 26.2 4.0 3.0 4.6 4.4 3.0 4.6 6.4 3.7 4.0 2.8 4.4 4.1 3.3 8.7 5.5 3.5 4.5 4.8 2.1 7.6 8.8 17.0 8.3 6.5 8.7 9.3 7.8 9.0 8.8 7.8 11.2 44.5 25.6 24.2 95.6 42.4 40.0 31.4 18.7 38.7 43.8 24.8 26.7 10.8 22.8 23.5 16.5 39.6 29.3 39.5 42.1 11.7 20.7 2.8 23.7 59.5 34.1 18.7 29.7 161.8 22.2 26.7 33.8 23.9 39.6 22.2 30.3 31.4 21.5 18.6 28.6 166.8 27.9 8.2 16.9 22.0 4.8 49.4 25.1 16.0 231.4 27.2 25.6 42.2 223.2 188.4 27.4 17.5 32.4 53.1 27.2 24.2 13.2 14.5 68.1 26.3 67.1 36.2 54.8 50.5 27.5 36.7 31.7 39.2 16.0 23.4 24.3 STARD7 GTT1 ENSG00000084090 "StAR related lipid transfer domain containing 7" Q9NQZ5 2 96184859-96208827 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033965, HPA064958, HPA064978" Supported Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB033965: AB_2302780, HPA064958: AB_2685391, HPA064978: AB_2685397" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.56e-5)" "prognostic favorable (3.89e-6)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (2.72e-3)" "unprognostic (2.38e-1)" "unprognostic (2.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.78e-1)" "prognostic favorable (4.38e-6)" "unprognostic (1.02e-1)" "unprognostic (2.04e-1)" "unprognostic (2.64e-2)" "unprognostic (2.42e-2)" 44.7 54.3 57.8 46.7 62.4 34.3 43.9 61.9 53.2 33.9 60.6 57.6 55.7 29.8 30.5 36.8 44.0 29.1 98.5 49.8 61.4 80.3 62.8 61.1 70.6 56.4 55.5 29.4 42.2 69.7 23.6 29.3 54.9 39.0 56.2 54.4 65.2 45.7 202.5 35.2 45.4 37.6 60.5 53.1 44.6 21.1 66.9 56.2 56.6 174.0 86.9 42.1 27.0 74.4 128.8 79.1 102.3 106.2 134.9 66.9 150.1 122.6 107.0 121.2 129.6 188.8 117.7 228.7 129.0 98.6 95.8 102.3 183.3 106.4 157.3 147.2 131.9 204.1 74.3 218.3 62.2 158.1 106.9 65.4 77.9 101.0 99.1 77.2 123.2 92.6 211.1 89.2 108.8 113.0 175.9 161.0 173.3 110.3 115.2 171.6 156.4 227.1 73.2 162.2 191.6 90.5 62.5 201.8 115.8 126.0 60.5 171.6 103.8 100.1 100.4 112.0 125.8 113.9 114.0 201.7 92.8 174.9 112.6 35.6 25.4 22.7 25.6 30.2 26.1 42.6 21.5 26.6 36.2 37.8 23.6 23.4 3.0 30.8 19.9 42.2 41.5 26.0 57.8 62.4 61.9 53.2 49.8 61.4 56.4 55.5 54.9 60.5 66.9 74.4 32.0 134.6 44.2 21.5 71.2 63.7 43.2 34.3 101.9 39.5 58.1 50.2 176.9 55.8 47.1 46.0 108.4 35.8 83.8 63.3 74.3 32.4 2.5 34.5 43.2 49.9 44.4 48.6 25.6 38.0 40.3 31.3 37.8 48.6 15.8 45.4 41.7 114.7 71.0 40.4 23.8 58.4 24.4 122.4 102.3 6.9 23.3 54.4 42.7 20.6 95.8 38.4 30.9 19.1 42.6 35.8 26.6 25.2 120.6 68.4 50.1 65.7 31.8 58.1 26.3 43.5 43.0 22.7 35.1 75.4 57.4 35.4 62.9 36.8 81.9 38.8 STATH STR ENSG00000126549 Statherin P02808 4 69995966-70002570 "Plasma proteins, Predicted secreted proteins, Transporters" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 925 "salivary gland: 9143.2" "Group enriched" "Detected in some" 9 "Breast glandular cells: 9.8;Early spermatids: 2.8" "Group enriched" "Detected in some" 14 "head and neck cancer: 3.5;lung cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044569 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Mammary glandular cells - Lactation" "HPA044569: AB_10966146" "unprognostic (2.00e-2)" 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 2.1 9.8 0.0 5.6 0.8 0.0 0.1 0.0 0.0 9143.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 3.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 9.8 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STC1 STC ENSG00000159167 "Stanniocalcin 1" P52823 8 23841929-23854806 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 64.3" "Cell type enhanced" "Detected in many" "Adipocytes: 162.2;Collecting duct cells: 97.5;Endometrial ciliated cells: 84.0;Endothelial cells: 242.0;Glandular and luminal cells: 301.5;Theca cells: 214.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 348.4;hTEC/SVTERT24-B: 201.7;U-251 MG: 145.4;U-87 MG: 623.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB018625, HPA023918" Approved "Secreted in other tissues" NA NA 240000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "CAB018625: AB_2197536, HPA023918: AB_1857566" "unprognostic (1.18e-1)" "prognostic unfavorable (8.45e-4)" "unprognostic (3.58e-2)" "unprognostic (2.13e-1)" "prognostic unfavorable (6.44e-5)" "prognostic unfavorable (6.32e-4)" "unprognostic (2.84e-2)" "prognostic unfavorable (1.53e-4)" "unprognostic (4.82e-2)" "unprognostic (1.44e-2)" "unprognostic (7.61e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.23e-6)" "prognostic unfavorable (5.55e-4)" "unprognostic (2.79e-1)" "unprognostic (1.19e-3)" "unprognostic (8.95e-3)" 44.7 3.1 2.1 2.6 1.4 0.1 26.2 2.0 5.8 49.4 13.8 7.4 1.7 32.4 0.6 7.0 5.9 14.8 25.7 4.1 3.9 17.9 4.0 10.5 0.7 4.5 4.3 2.8 13.7 10.5 28.9 29.1 4.5 9.3 1.9 8.3 10.3 7.3 2.6 3.0 2.9 7.5 3.4 0.2 10.4 0.2 4.7 1.5 64.3 6.4 1.3 44.4 10.2 2.9 1.5 1.3 1.9 0.0 13.0 14.3 0.3 20.6 348.4 6.7 31.5 0.1 0.0 0.1 30.0 6.8 116.6 1.1 0.8 5.1 58.0 2.2 0.4 0.1 0.0 0.0 0.9 0.0 0.5 65.1 0.0 201.7 0.5 96.4 2.8 0.0 0.6 0.5 28.8 0.0 0.0 0.1 8.4 0.0 1.0 0.0 0.3 0.0 11.7 0.0 0.8 0.0 31.4 2.1 2.1 2.3 21.3 0.4 27.0 82.3 3.1 1.6 145.4 0.0 0.1 0.1 623.7 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.4 2.0 5.8 4.1 3.9 4.5 4.3 4.5 3.4 4.7 2.9 162.2 3.2 13.6 0.0 0.2 22.7 2.4 15.7 0.0 3.1 75.3 8.0 3.3 32.9 3.7 97.5 0.0 0.9 0.0 0.8 0.0 37.0 0.1 84.0 42.7 242.0 0.0 0.0 0.2 0.2 6.1 67.9 2.6 301.5 1.3 0.2 23.2 0.0 2.5 8.4 0.3 0.0 0.0 0.3 25.8 0.2 5.0 1.5 17.8 0.0 0.0 0.9 0.0 0.0 0.1 6.7 0.0 0.0 1.2 7.6 0.0 0.1 0.5 2.1 0.0 0.5 7.4 0.0 0.0 0.3 20.6 1.9 2.6 214.5 1.0 9.6 STC2 STC-2 ENSG00000113739 "Stanniocalcin 2" O76061 5 173314723-173328447 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 143.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 278.3;Breast myoepithelial cells: 119.6;Extravillous trophoblasts: 59.5" "Cancer enriched" "Detected in all" 6 "breast cancer: 91.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 1019.9;T-47d: 940.0;U-138 MG: 382.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA045372 Approved Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA 19000000 "Cluster 5: Breast - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "Endoplasmic reticulum" "HPA045372: AB_10961040" "prognostic favorable (7.40e-5)" "unprognostic (2.40e-2)" "unprognostic (9.03e-3)" "unprognostic (1.21e-1)" "unprognostic (1.89e-3)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (3.07e-5)" "unprognostic (5.28e-3)" "unprognostic (6.12e-3)" "unprognostic (1.53e-1)" "unprognostic (2.13e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.17e-8)" "prognostic unfavorable (7.57e-4)" "unprognostic (8.56e-2)" "unprognostic (5.06e-2)" "unprognostic (7.93e-3)" 7.4 1.7 0.7 2.4 0.9 0.0 143.6 2.2 3.1 13.2 1.9 4.8 0.6 3.0 0.3 2.0 2.0 6.4 9.9 3.0 1.8 3.6 0.8 11.3 1.1 5.0 6.4 0.7 32.6 3.3 1.7 28.0 3.7 4.8 0.6 7.7 1.0 6.7 4.4 12.8 2.7 21.2 1.3 11.5 3.4 0.7 2.9 0.2 9.1 4.9 0.3 4.7 3.0 3.0 52.5 15.3 2.7 13.0 47.9 20.5 133.8 234.5 239.4 59.1 115.0 74.4 36.7 0.0 33.4 139.8 298.2 21.5 33.8 72.0 102.5 0.1 18.9 0.0 26.7 50.2 311.3 15.8 4.3 43.6 117.9 133.3 7.9 274.4 16.7 42.4 2.4 0.1 1019.9 41.6 0.7 0.7 7.9 23.4 73.2 0.3 36.5 27.4 0.0 3.9 35.6 9.6 10.3 1.1 42.5 10.4 940.0 15.9 151.5 382.8 1.3 229.1 49.2 42.0 24.3 10.5 74.6 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 2.2 3.1 3.0 1.8 5.0 6.4 3.7 1.3 2.9 3.0 6.9 0.0 0.0 0.0 0.4 5.0 0.2 4.9 0.6 11.1 278.3 119.6 27.1 0.0 0.6 0.0 0.0 37.0 2.4 0.4 0.0 31.6 0.6 9.5 1.0 25.3 7.2 0.0 0.2 13.1 59.5 16.7 0.0 16.1 0.0 0.0 3.6 0.0 5.2 0.0 0.2 0.2 0.0 0.0 4.8 1.0 23.0 0.5 10.6 1.0 0.0 0.9 0.0 0.0 0.1 7.8 0.0 0.4 0.0 0.8 0.0 4.5 0.2 2.4 0.0 2.3 24.6 0.7 0.8 0.5 6.3 21.9 1.0 0.9 0.4 0.5 STING1 "ERIS, FLJ38577, MITA, MPYS, NET23, STING, TMEM173" ENSG00000184584 "Stimulator of interferon response cGAMP interactor 1" Q86WV6 5 139475533-139482935 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Host-virus interaction, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 25.3;Cardiomyocytes: 27.7;dendritic cells: 17.0;Hofbauer cells: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 64.4;EFO-21: 83.8;HDLM-2: 200.5;THP-1: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038116, HPA038534" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA038116: AB_2675841, HPA038534: AB_2676067" "unprognostic (1.45e-1)" "unprognostic (4.10e-3)" "unprognostic (1.29e-1)" "unprognostic (2.23e-2)" "unprognostic (2.70e-2)" "unprognostic (1.71e-2)" "unprognostic (7.66e-2)" "unprognostic (2.77e-2)" "unprognostic (6.30e-2)" "unprognostic (1.01e-1)" "unprognostic (5.69e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.59e-8)" "unprognostic (9.18e-3)" "unprognostic (4.14e-2)" "unprognostic (4.45e-2)" "unprognostic (1.34e-1)" 38.9 9.3 4.6 18.4 5.0 16.9 26.2 4.4 5.4 32.6 12.8 16.6 6.7 25.0 6.8 21.5 36.2 11.9 35.7 4.3 4.9 17.3 5.5 48.1 15.0 5.5 4.9 21.9 5.4 3.3 11.8 12.9 5.1 20.7 11.6 0.3 24.5 15.5 7.5 15.5 19.0 18.7 5.3 37.8 11.6 3.1 6.0 12.4 20.2 8.5 27.1 21.7 28.4 4.8 2.9 0.7 0.2 0.0 4.0 12.0 0.2 15.3 64.4 7.6 24.4 0.0 18.8 0.0 83.8 49.0 1.9 10.8 0.4 22.9 4.8 200.5 3.3 13.5 6.6 0.8 7.5 4.1 0.8 16.2 1.2 4.6 5.7 12.8 27.8 1.4 3.9 58.3 33.6 0.0 2.2 24.1 0.1 0.8 4.7 0.7 6.1 18.0 9.4 7.0 5.8 0.0 6.5 5.3 16.0 0.6 0.7 73.3 17.2 1.9 1.3 6.8 5.6 0.0 20.0 0.1 0.3 56.2 11.3 16.6 60.9 0.1 56.9 40.0 29.3 0.6 57.4 47.8 55.6 0.3 40.3 35.0 5.0 90.6 17.5 19.2 65.3 60.6 4.6 5.0 4.4 5.4 4.3 4.9 5.5 4.9 5.1 5.3 6.0 4.8 25.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 0.0 0.0 0.0 0.0 0.8 17.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.6 8.4 0.0 0.0 0.0 0.0 0.0 0.0 67.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.8 5.8 0.0 0.0 0.0 STK32C "MGC23665, PKE, YANK3" ENSG00000165752 "Serine/threonine kinase 32C" Q86UX6 10 132207492-132331847 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 54.1" "Group enriched" "Detected in many" 4 "Early spermatids: 278.9;Late spermatids: 83.3;Spermatocytes: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 55.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017894 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "HPA017894: AB_1857591" "unprognostic (2.11e-1)" "unprognostic (8.40e-2)" "unprognostic (4.80e-3)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.65e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (1.68e-6)" "unprognostic (2.03e-1)" "unprognostic (7.79e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (5.31e-6)" "unprognostic (8.65e-2)" "unprognostic (3.20e-1)" "unprognostic (5.05e-2)" "unprognostic (1.36e-1)" 11.0 12.5 31.4 7.1 39.6 7.6 8.9 17.8 37.5 8.1 13.5 9.1 5.2 6.9 14.8 5.4 9.4 6.5 7.4 31.3 23.2 15.6 5.0 8.8 10.0 24.6 26.1 6.7 7.4 6.0 12.3 4.9 20.5 6.6 4.7 7.9 5.7 5.2 13.7 7.6 6.8 5.0 23.4 15.1 6.2 54.1 30.9 10.8 6.4 9.1 6.4 8.3 6.5 25.9 69.4 43.5 13.3 33.5 18.4 23.3 2.7 14.1 10.7 17.4 22.2 10.0 46.0 14.8 10.3 16.4 22.0 14.9 18.6 5.5 16.9 8.9 31.1 8.9 46.1 47.1 22.9 7.9 31.1 17.6 20.8 15.7 17.3 22.0 15.6 25.1 15.4 10.2 19.0 21.1 10.4 30.4 8.8 12.6 31.4 12.2 8.2 4.9 23.3 11.7 34.6 27.3 10.2 9.3 20.9 7.9 10.5 19.2 10.6 13.6 14.2 18.2 11.3 19.1 3.8 38.7 31.4 7.4 7.1 55.3 17.9 16.5 5.8 19.6 7.3 6.2 4.7 6.6 25.1 10.2 5.8 4.5 2.4 6.1 17.3 14.5 9.2 7.0 31.4 39.6 17.8 37.5 31.3 23.2 24.6 26.1 20.5 23.4 30.9 25.9 6.6 0.0 7.2 13.4 7.3 5.2 6.8 5.7 4.6 8.4 10.3 11.0 3.7 2.8 6.1 12.9 12.5 3.4 9.3 3.2 19.6 5.4 278.9 25.9 8.2 8.2 19.2 15.8 22.9 8.7 2.3 7.2 6.6 11.8 15.8 6.0 13.6 5.5 14.6 37.0 13.9 7.4 12.2 24.3 28.5 83.3 9.0 14.8 12.4 7.5 14.0 11.0 6.2 9.5 10.0 6.0 5.1 6.8 4.8 11.4 3.8 13.2 13.7 14.6 6.6 10.5 5.6 89.8 20.0 5.9 5.1 1.5 9.3 10.1 7.6 7.3 STMND1 FLJ23152 ENSG00000230873 "Stathmin domain containing 1" H3BQB6 6 17102050-17131378 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 17.8;gallbladder: 5.3;testis: 5.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 93.8;Respiratory ciliated cells: 72.8;Spermatocytes: 18.7;Spermatogonia: 23.8" "Group enriched" "Detected in some" 6 "breast cancer: 4.1;endometrial cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HEK 293: 2.4;SCLC-21H: 6.0;T-47d: 7.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA067970 Enhanced Approved "Actin filaments" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "HPA067970: AB_2685934" "unprognostic (7.70e-2)" "unprognostic (1.03e-1)" "unprognostic (2.70e-2)" "unprognostic (2.09e-3)" "unprognostic (6.88e-2)" "unprognostic (6.64e-2)" "unprognostic (4.29e-2)" "unprognostic (4.22e-2)" "unprognostic (3.13e-2)" "unprognostic (1.22e-1)" "unprognostic (9.72e-2)" "unprognostic (5.29e-4)" "unprognostic (7.14e-2)" "unprognostic (1.10e-2)" "unprognostic (2.19e-2)" 0.0 0.0 0.2 0.1 0.2 0.0 3.0 0.3 0.4 0.8 2.2 0.9 0.1 0.5 0.3 0.0 17.8 5.3 0.0 0.3 0.2 0.0 0.1 2.4 0.0 0.5 0.5 0.0 3.5 0.0 0.5 0.1 0.3 0.0 0.8 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.5 0.0 0.0 5.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.2 0.5 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.5 7.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.0 0.0 0.2 0.2 0.3 0.4 0.3 0.2 0.5 0.5 0.3 0.5 0.2 0.6 0.0 0.0 1.3 0.0 0.0 0.0 1.7 2.9 0.0 0.1 5.0 1.4 0.7 2.8 8.3 0.0 0.0 0.0 0.0 1.2 0.0 0.6 1.3 93.8 0.9 0.5 1.8 0.0 0.5 0.2 0.0 0.4 0.0 2.3 0.0 0.7 0.0 0.3 0.0 0.0 0.2 0.7 2.0 0.0 0.4 2.8 0.0 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.6 0.3 0.4 0.0 0.7 0.0 0.0 72.8 0.0 6.6 1.3 2.7 18.7 23.8 0.0 0.9 0.0 0.3 0.0 1.8 0.6 STMP1 "C7orf73, Mm47, PL-5283" ENSG00000243317 "Short transmembrane mitochondrial protein 1" E0CX11 7 135662496-135693418 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 249.0;Distal tubular cells: 197.6;Extravillous trophoblasts: 261.3;Hofbauer cells: 185.2;Proximal tubular cells: 209.5;Syncytiotrophoblasts: 275.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 431.7;eosinophil: 127.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 431.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065565 Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA065565: AB_2685512" "unprognostic (3.94e-2)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (3.11e-2)" "unprognostic (3.64e-2)" "unprognostic (1.81e-1)" "unprognostic (2.99e-3)" "unprognostic (1.12e-1)" "unprognostic (4.43e-3)" "prognostic favorable (2.95e-4)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (7.21e-3)" "unprognostic (4.90e-2)" "unprognostic (9.99e-2)" "unprognostic (9.62e-3)" "unprognostic (6.81e-2)" 15.7 28.5 15.5 17.7 17.3 41.3 22.9 15.8 20.5 21.1 17.9 19.8 18.2 16.1 25.7 46.7 15.9 16.6 25.4 15.2 17.2 27.9 32.0 15.2 21.2 17.6 16.4 12.9 15.1 18.5 19.0 19.8 18.1 20.3 22.5 19.2 21.0 15.0 48.4 21.5 19.2 16.4 16.9 14.7 20.4 23.8 16.6 28.8 32.2 32.8 26.2 20.0 27.4 17.6 41.5 19.4 44.9 42.4 52.6 73.2 27.3 44.8 43.5 36.3 37.8 12.0 45.2 38.3 39.3 68.7 35.6 17.0 43.9 57.0 48.9 48.2 36.1 59.4 20.4 28.8 51.7 61.3 36.8 46.0 63.6 43.6 40.4 54.9 30.5 48.5 65.3 33.0 80.9 54.0 87.6 69.5 88.6 57.4 48.5 43.6 48.0 63.0 102.2 21.5 56.6 54.7 60.8 41.3 43.9 43.1 16.9 66.0 51.1 35.3 29.0 63.5 63.2 38.1 58.5 72.9 109.1 63.1 65.9 431.7 57.3 127.7 23.8 61.2 22.8 24.9 22.5 24.3 61.0 21.0 21.0 24.1 44.6 38.9 68.1 34.5 33.1 50.9 15.5 17.3 15.8 20.5 15.2 17.2 17.6 16.4 18.1 16.9 16.6 17.6 67.4 41.7 47.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 128.9 145.3 0.0 0.0 27.9 97.5 0.0 249.0 57.2 0.0 197.6 164.3 0.0 102.2 97.3 39.4 0.0 0.0 0.0 97.4 261.3 43.9 0.0 90.8 56.8 80.1 0.0 0.0 185.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.7 0.0 0.0 146.8 0.0 0.0 0.0 0.0 131.8 0.0 0.0 6.4 0.0 0.0 209.5 34.2 0.0 0.0 0.0 53.0 0.0 0.0 0.0 0.0 275.4 29.8 65.8 0.0 0.0 STOML2 "HSPC108, SLP-2" ENSG00000165283 "Stomatin like 2" Q9UJZ1 9 35099776-35103195 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015944, HPA062016" Supported Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 44000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "CAB015944: , HPA062016: AB_2684659" "unprognostic (2.49e-1)" "unprognostic (2.69e-1)" "unprognostic (1.20e-2)" "unprognostic (9.43e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (5.14e-2)" "unprognostic (4.25e-2)" "unprognostic (1.04e-2)" "unprognostic (9.06e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.00e-5)" "unprognostic (2.74e-2)" "unprognostic (5.26e-1)" "unprognostic (2.67e-1)" "unprognostic (5.47e-2)" 63.6 93.3 45.4 39.1 46.2 66.7 62.0 47.5 49.0 58.4 61.3 75.3 55.6 64.2 49.4 84.7 57.3 33.2 123.4 46.2 46.6 75.4 99.2 43.7 46.6 44.7 45.9 59.4 69.5 71.9 42.3 46.2 45.3 49.0 67.2 23.5 59.3 48.4 171.2 71.0 61.2 54.0 45.9 53.1 75.8 42.8 48.2 55.1 48.6 111.7 59.5 64.5 56.5 45.4 219.6 248.1 130.3 195.7 93.3 111.1 139.5 105.9 153.5 292.6 212.5 283.2 99.6 183.2 72.9 135.2 210.6 91.4 201.3 235.8 193.7 158.1 185.0 112.7 202.6 269.7 272.1 215.8 124.0 141.9 181.1 238.6 283.2 92.2 193.8 183.6 186.5 109.1 144.8 176.0 193.5 377.6 205.3 162.4 155.2 166.6 110.3 197.0 159.5 128.9 120.4 146.3 60.0 158.0 141.7 92.5 109.7 139.1 106.2 99.7 141.1 84.4 190.4 76.1 140.3 173.8 132.7 134.3 137.1 67.8 73.0 42.5 64.7 65.8 77.8 91.4 73.1 74.1 98.0 87.0 69.2 63.8 12.9 98.1 49.3 121.8 115.5 114.4 45.4 46.2 47.5 49.0 46.2 46.6 44.7 45.9 45.3 45.9 48.2 45.4 63.9 41.7 33.1 6.5 66.8 96.4 123.8 172.9 83.6 36.6 104.5 118.7 83.4 108.7 92.5 49.7 8.4 233.6 48.3 116.1 250.5 144.3 77.2 72.7 76.3 66.4 98.8 106.2 7.8 153.4 245.2 74.9 66.3 47.3 84.3 111.3 61.4 111.3 132.7 18.5 8.1 145.9 73.2 41.0 68.3 22.9 75.2 47.9 99.6 5.6 84.5 83.9 56.7 2.5 8.8 137.2 117.5 69.6 126.1 177.6 197.7 290.1 85.8 37.1 52.6 66.5 95.6 73.1 110.0 119.2 114.5 166.4 51.2 153.2 222.2 148.7 STOX1 "C10orf24, FLJ25162" ENSG00000165730 "Storkhead box 1" Q6ZVD7 10 68827531-68895432 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.2;choroid plexus: 30.8" "Group enriched" "Detected in many" 5 "Astrocytes: 85.2;Endometrial ciliated cells: 67.4;Respiratory ciliated cells: 42.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 8.6;HAP1: 8.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA037844, HPA037845" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Intracellular and membrane" No NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA037844: AB_2675700, HPA037845: AB_10671369" "prognostic favorable (3.37e-5)" "unprognostic (5.53e-3)" "unprognostic (6.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.63e-3)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "prognostic favorable (2.08e-4)" "unprognostic (1.52e-1)" "unprognostic (2.45e-3)" "unprognostic (5.33e-3)" "unprognostic (5.29e-2)" "unprognostic (3.87e-2)" "unprognostic (8.77e-2)" "unprognostic (3.06e-2)" "unprognostic (2.33e-1)" "unprognostic (3.46e-2)" 6.3 5.1 26.4 0.5 23.6 0.2 4.2 14.9 33.2 1.9 30.8 1.6 1.1 1.6 7.4 1.4 12.5 0.9 0.4 23.9 22.4 2.8 0.3 1.3 1.2 16.5 24.9 1.1 1.4 6.5 7.2 0.8 17.4 1.2 1.6 0.7 1.6 1.1 1.3 0.9 2.1 0.8 16.3 0.4 3.4 2.5 26.2 6.7 3.1 0.8 1.0 2.5 0.7 20.5 1.8 2.0 4.2 8.6 1.8 0.0 2.5 0.2 0.1 1.2 1.3 1.8 2.6 1.7 2.4 0.0 3.3 0.5 8.1 0.0 0.6 2.0 3.4 0.1 0.4 2.6 0.2 2.3 3.1 0.2 0.1 0.2 0.0 0.2 0.1 4.5 0.4 0.2 0.1 1.8 3.9 2.8 1.4 0.4 1.2 2.8 0.1 0.0 2.6 4.6 1.3 3.9 3.1 0.8 0.6 2.7 1.9 1.8 0.0 0.0 0.2 0.0 1.3 0.7 1.6 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.8 0.4 0.0 0.0 0.0 1.0 0.0 0.0 26.4 23.6 14.9 33.2 23.9 22.4 16.5 24.9 17.4 16.3 26.2 20.5 0.3 0.0 0.5 85.2 0.3 1.5 4.5 0.9 1.2 0.7 5.1 4.1 0.5 0.0 5.6 1.8 0.0 1.6 3.1 0.4 3.9 0.1 0.3 67.4 1.7 0.4 0.0 1.7 11.4 0.4 0.5 0.6 0.5 4.2 2.5 0.8 0.0 0.2 0.1 0.0 9.9 2.5 2.0 0.3 0.7 0.7 1.2 0.2 0.0 1.9 0.1 1.9 2.1 6.0 2.1 0.1 0.3 0.0 0.6 1.7 0.8 1.8 42.8 0.4 6.6 1.5 5.0 1.4 8.8 0.4 0.4 1.2 0.7 6.9 5.3 1.8 STOX2 DKFZp762K222 ENSG00000173320 "Storkhead box 2" Q9P2F5 4 183797692-184023526 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 181.7;Inhibitory neurons: 192.3;Microglial cells: 72.1;Oligodendrocyte precursor cells: 91.0;Oligodendrocytes: 153.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;HeLa: 12.7;NTERA-2: 16.8;SH-SY5Y: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049776, HPA065002" Uncertain Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Actin filaments" "HPA049776: AB_2680875, HPA065002: " "unprognostic (9.79e-3)" "unprognostic (3.46e-1)" "unprognostic (2.10e-1)" "unprognostic (6.57e-3)" "unprognostic (3.33e-1)" "unprognostic (6.41e-2)" "unprognostic (4.57e-4)" "unprognostic (8.97e-3)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (3.75e-2)" "unprognostic (1.86e-1)" "unprognostic (7.06e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "unprognostic (2.52e-3)" "unprognostic (2.49e-1)" 1.8 1.6 8.3 0.7 8.2 6.0 1.8 4.2 13.3 2.1 2.3 1.7 0.9 1.9 3.4 5.0 2.7 1.3 3.6 11.1 3.1 2.7 2.0 2.1 0.6 2.7 3.9 3.3 4.9 4.0 7.0 1.4 3.9 2.3 0.9 3.8 7.3 2.3 2.1 3.9 1.3 1.8 2.0 4.1 2.3 0.9 6.6 4.1 5.8 2.1 1.1 2.5 3.3 11.5 2.1 4.3 13.2 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.3 1.7 0.0 2.6 0.0 2.7 0.2 7.4 1.2 0.0 0.0 5.9 0.0 12.7 0.1 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.5 0.0 1.8 0.0 0.6 0.0 0.1 16.8 0.0 0.6 0.1 4.8 0.0 3.1 4.1 6.8 15.8 3.2 0.0 0.0 4.7 0.2 0.4 0.0 0.0 2.8 0.0 0.1 0.1 3.8 2.1 0.6 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 8.2 4.2 13.3 11.1 3.1 2.7 3.9 3.9 2.0 6.6 11.5 12.7 12.8 22.1 39.2 0.4 4.2 6.0 3.7 8.6 28.2 3.8 4.6 20.7 5.7 8.7 7.3 0.0 2.7 0.0 0.2 3.9 5.4 1.2 7.2 0.7 18.5 1.8 0.0 181.7 3.1 2.1 5.8 3.1 3.7 0.0 0.3 21.4 5.6 1.1 33.7 192.3 0.4 2.0 2.2 1.5 2.6 0.6 0.8 1.8 72.1 0.0 12.4 0.0 91.0 153.5 2.1 0.0 4.5 1.3 5.2 0.0 4.0 16.8 3.4 0.0 4.8 4.5 0.6 2.0 17.8 3.3 0.7 0.7 3.6 0.4 3.4 STRC DFNB16 ENSG00000242866 Stereocilin Q7RTU9 15 43599563-43618800 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 9.0;pituitary gland: 4.4;retina: 3.6;testis: 5.0" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Excitatory neurons: 55.7;Inhibitory neurons: 35.4;Oligodendrocyte precursor cells: 13.0;Oligodendrocytes: 15.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048083 Enhanced NA NA "Cluster 6: Brain - Smell perception" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA048083: AB_2732545" "unprognostic (8.60e-3)" "unprognostic (5.77e-3)" "unprognostic (6.14e-2)" "unprognostic (1.60e-2)" "unprognostic (1.47e-1)" "unprognostic (1.15e-3)" "unprognostic (1.65e-1)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.84e-2)" "unprognostic (5.92e-3)" "unprognostic (1.99e-4)" "unprognostic (1.58e-1)" "unprognostic (6.56e-2)" "unprognostic (1.78e-1)" "unprognostic (1.59e-4)" 0.1 0.6 3.5 0.0 3.8 0.0 0.3 9.0 8.0 0.3 0.3 0.3 0.1 0.1 1.0 0.2 0.4 0.0 0.1 3.8 2.4 0.5 0.6 0.1 0.0 3.8 2.2 0.6 0.2 0.0 4.4 0.0 3.7 1.0 0.0 3.6 0.7 0.0 0.4 0.7 0.4 0.0 1.5 0.3 0.3 5.0 3.2 0.6 1.0 0.0 0.0 0.1 0.3 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.8 9.0 8.0 3.8 2.4 3.8 2.2 3.7 1.5 3.2 4.8 0.2 0.0 0.0 10.1 0.0 0.6 0.1 0.2 0.0 2.6 0.6 0.9 0.3 0.0 0.2 0.0 6.2 0.3 0.0 0.1 0.0 0.1 0.5 0.3 0.1 0.2 0.0 0.0 55.7 0.2 0.1 0.1 0.0 0.3 0.0 2.0 0.4 0.3 0.1 3.3 35.4 0.2 0.0 0.3 0.2 0.5 0.0 0.1 1.8 6.5 0.0 2.3 0.0 13.0 15.4 0.2 1.3 0.4 0.1 0.2 0.7 0.1 0.3 8.7 0.0 0.2 0.1 4.5 0.9 0.0 0.4 0.7 0.2 0.0 0.1 0.0 STX5 "SED5, STX5A" ENSG00000162236 "Syntaxin 5" Q13190 11 62806860-62832051 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001358 Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" Nucleoplasm "HPA001358: AB_1080119" "unprognostic (3.51e-2)" "unprognostic (4.23e-2)" "unprognostic (1.79e-1)" "unprognostic (1.91e-3)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.71e-2)" "unprognostic (3.30e-1)" "unprognostic (1.13e-1)" "unprognostic (3.34e-2)" "unprognostic (1.01e-1)" "unprognostic (2.19e-1)" "unprognostic (1.67e-2)" "unprognostic (3.42e-2)" "unprognostic (2.79e-1)" "unprognostic (2.86e-2)" "unprognostic (8.22e-3)" 34.2 31.8 31.2 22.2 32.1 41.9 34.4 35.3 39.0 42.0 34.6 27.5 22.7 30.6 42.6 34.9 33.1 25.0 27.2 31.3 32.1 38.3 51.0 32.7 25.1 34.2 31.8 42.2 51.1 27.0 29.6 27.4 31.7 43.6 22.4 18.8 51.8 26.9 27.7 41.4 28.4 23.9 31.3 35.5 36.0 29.0 32.9 30.4 37.9 20.2 31.6 28.4 34.2 33.5 40.9 25.4 34.5 29.9 44.6 50.2 31.0 39.2 54.9 64.7 52.0 18.8 39.0 26.0 35.9 55.9 37.8 41.7 29.7 37.2 47.8 60.4 28.3 23.0 33.0 39.2 55.3 26.9 33.5 40.7 41.6 58.6 70.3 50.5 31.9 37.0 21.0 71.7 34.5 48.4 36.5 43.8 11.3 36.2 36.8 37.1 32.3 70.2 28.8 20.7 26.3 21.6 31.4 49.4 63.6 25.7 54.4 35.9 36.8 46.8 24.6 54.6 25.1 64.2 38.1 27.4 38.0 18.7 29.6 11.7 11.4 36.2 10.4 14.1 9.3 11.0 8.1 10.1 10.4 11.3 7.5 7.6 17.8 13.1 12.7 12.9 13.0 6.6 31.2 32.1 35.3 39.0 31.3 32.1 34.2 31.8 31.7 31.3 32.9 33.5 30.3 22.4 29.3 12.7 64.1 67.2 79.5 37.9 13.6 21.0 38.0 27.9 5.6 20.0 27.6 11.0 27.1 55.3 57.6 29.8 29.4 45.7 113.1 28.2 28.6 33.1 32.9 23.5 16.0 59.6 75.1 39.5 23.9 34.0 52.7 25.2 30.0 24.4 46.5 18.5 15.4 54.8 22.4 39.5 53.5 143.7 39.1 33.2 46.2 12.2 51.6 30.3 44.3 10.1 16.6 44.1 36.0 25.2 47.2 61.2 44.8 32.6 20.7 18.6 32.9 34.1 33.6 32.2 30.1 19.8 64.2 177.6 40.4 28.0 26.2 75.5 STXBP5 "LLGL3, tomosyn" ENSG00000164506 "Syntaxin binding protein 5" Q5T5C0 6 147204425-147390476 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 115.8" "Cell type enhanced" "Detected in many" "Astrocytes: 325.8;Excitatory neurons: 441.9;Inhibitory neurons: 300.1;Oligodendrocyte precursor cells: 206.1;Oligodendrocytes: 150.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basophil: 3.8;eosinophil: 9.2;neutrophil: 3.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "HEL: 210.2;HMC-1: 219.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039991, HPA049727, CAB079016" Enhanced Supported Enhanced Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB079016: , HPA039991: AB_10673368, HPA049727: AB_2680863" "prognostic unfavorable (4.48e-4)" "unprognostic (4.60e-3)" "unprognostic (2.28e-3)" "unprognostic (1.14e-1)" "unprognostic (2.21e-1)" "unprognostic (1.52e-1)" "unprognostic (9.56e-4)" "unprognostic (6.01e-2)" "unprognostic (3.60e-1)" "unprognostic (2.74e-2)" "unprognostic (1.70e-2)" "unprognostic (6.37e-3)" "prognostic unfavorable (2.74e-7)" "unprognostic (8.01e-2)" "unprognostic (1.74e-1)" "unprognostic (2.55e-1)" "unprognostic (1.35e-3)" 7.0 9.1 7.2 9.5 12.7 34.3 7.8 24.2 13.2 9.5 0.0 14.2 8.0 8.3 7.7 13.7 5.9 9.5 5.9 9.5 6.5 3.6 3.9 6.6 7.8 0.6 0.5 5.5 15.5 115.8 7.7 6.3 0.5 11.4 16.3 20.1 5.5 14.5 7.7 15.4 11.2 10.9 0.0 8.3 8.0 22.2 0.6 9.4 6.3 8.1 9.6 8.5 9.9 8.5 10.8 9.4 4.9 16.5 23.4 48.8 5.4 24.5 36.1 17.8 19.9 8.0 7.0 7.8 5.6 48.8 30.5 12.7 14.1 21.5 21.6 17.1 11.0 210.2 27.2 9.0 26.8 72.7 219.6 35.6 15.0 35.6 72.0 42.1 23.2 12.2 57.8 9.6 35.4 15.7 11.6 18.8 4.0 8.9 21.4 1.7 25.4 3.0 9.7 18.4 10.6 7.6 18.9 13.3 8.2 8.7 3.9 28.0 26.9 25.4 9.2 12.6 22.5 7.9 0.1 9.1 14.0 26.2 18.5 3.8 0.3 9.2 0.9 0.4 0.9 0.3 0.5 1.1 0.4 0.9 0.8 1.3 3.1 0.4 0.5 0.3 0.2 0.3 7.2 12.7 24.2 13.2 9.5 6.5 0.6 0.5 0.5 0.0 0.6 8.5 12.1 16.0 8.8 325.8 5.7 3.6 2.6 1.9 3.4 38.8 6.7 7.7 14.1 11.5 6.7 16.5 31.3 5.2 9.5 18.7 0.0 4.8 39.0 10.1 10.5 10.8 41.1 10.1 441.9 12.9 4.6 10.1 14.3 20.5 44.2 5.1 8.9 4.5 4.7 33.7 300.1 30.3 0.0 7.8 3.1 42.8 7.8 7.8 10.6 97.4 8.5 5.4 6.2 206.1 150.4 11.7 21.4 7.2 5.8 10.4 29.3 1.9 2.2 29.0 13.1 12.7 5.6 13.1 11.5 11.0 6.7 3.8 9.3 5.4 19.3 3.6 SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 554.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 935.2;Proximal enterocytes: 647.5;Proximal tubular cells: 2949.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 350000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" 118.7 73.3 70.6 43.1 73.2 48.2 80.0 76.2 92.5 49.9 91.1 156.9 231.1 42.4 78.8 86.9 54.6 41.9 258.1 71.1 74.5 554.0 193.0 41.6 47.8 71.7 70.2 45.7 93.6 244.2 46.8 48.8 72.9 54.3 165.9 38.4 120.6 66.6 274.1 55.4 195.4 63.5 73.8 39.6 81.1 36.9 73.3 61.7 97.6 368.1 63.1 66.4 58.5 76.9 90.2 94.9 73.8 91.1 137.8 91.2 127.7 98.4 85.2 126.0 91.2 224.5 72.0 122.4 67.0 119.8 100.2 126.8 156.7 118.4 149.8 119.3 141.4 105.9 75.4 129.2 116.0 110.6 82.7 109.1 95.6 106.3 143.7 76.7 115.1 97.9 110.1 98.1 117.5 137.4 158.2 101.1 39.4 334.1 170.0 98.3 172.6 134.5 172.2 106.4 89.8 49.3 78.9 163.7 162.3 69.0 99.8 85.4 93.1 96.6 94.6 119.9 124.9 84.2 131.0 107.8 113.9 150.4 88.0 101.6 91.0 80.8 79.0 110.2 88.5 70.2 72.0 88.4 115.4 55.4 79.1 84.3 49.7 102.3 114.3 63.2 107.7 142.7 70.6 73.2 76.2 92.5 71.1 74.5 71.7 70.2 72.9 73.8 73.3 76.9 52.7 64.1 96.5 32.7 61.0 35.4 108.9 129.6 44.3 33.3 105.0 109.1 408.6 131.5 115.2 141.6 22.9 232.3 49.9 218.1 935.2 131.8 49.2 67.1 56.9 57.0 106.3 68.4 45.8 113.2 129.3 69.8 79.5 80.8 91.3 46.0 57.5 210.0 131.7 45.4 43.5 202.1 105.8 71.3 46.0 35.9 54.7 82.2 119.2 16.9 89.8 68.2 58.7 28.1 46.2 67.1 215.4 74.1 57.1 64.2 647.5 2949.2 83.7 36.1 52.6 61.1 98.3 138.9 54.4 111.3 41.3 188.4 64.4 90.7 388.7 111.0 SUDS3 "FLJ00052, SAP45, SDS3" ENSG00000111707 "SDS3 homolog, SIN3A corepressor complex component" Q9H7L9 12 118376555-118418033 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 271.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040402, HPA041972" Approved Supported "Nuclear bodies,Cytosol" "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies, Cytosol" "HPA040402: , HPA041972: AB_2677776" "unprognostic (1.49e-1)" "unprognostic (4.08e-3)" "unprognostic (1.09e-1)" "unprognostic (6.60e-2)" "unprognostic (7.39e-2)" "unprognostic (1.45e-1)" "unprognostic (3.05e-3)" "unprognostic (1.22e-1)" "unprognostic (2.74e-2)" "unprognostic (2.70e-1)" "unprognostic (8.71e-2)" "unprognostic (3.03e-1)" "unprognostic (2.36e-2)" "unprognostic (1.83e-2)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "unprognostic (2.37e-1)" 10.8 12.3 13.3 12.0 14.2 16.9 18.7 9.6 15.2 16.6 12.1 16.5 14.3 14.9 16.0 19.9 18.1 11.7 12.8 15.8 12.9 16.1 14.0 11.9 14.7 12.7 14.6 15.0 17.3 25.3 11.6 11.5 14.1 16.2 18.3 16.3 19.2 15.7 11.3 20.1 14.1 13.7 10.6 13.7 16.2 16.4 12.2 17.9 21.7 11.9 19.5 14.4 15.2 13.2 29.4 21.9 29.4 29.4 16.1 21.1 31.5 22.5 23.2 25.8 20.4 24.1 18.6 39.8 23.5 21.8 16.0 34.3 35.3 23.8 30.3 35.3 20.9 27.7 18.4 21.6 18.4 30.9 20.5 14.6 25.0 12.8 22.7 33.5 22.2 36.9 30.8 14.1 23.9 20.2 36.7 40.2 30.5 38.8 17.0 32.9 26.4 28.3 23.7 42.7 22.9 22.7 31.9 18.7 19.9 36.7 61.1 24.9 18.7 17.5 16.6 19.7 15.5 26.2 31.4 29.2 19.4 19.4 21.4 1.8 4.3 5.9 5.0 2.8 6.1 8.8 5.4 5.7 4.7 8.4 6.4 4.4 12.6 4.3 2.8 6.8 5.5 3.9 13.3 14.2 9.6 15.2 15.8 12.9 12.7 14.6 14.1 10.6 12.2 13.2 25.5 28.9 15.9 19.6 37.8 64.7 44.7 55.0 46.1 75.4 85.6 63.0 37.5 41.5 37.1 47.8 77.2 34.6 26.9 75.1 80.3 41.5 271.9 87.6 54.4 24.6 37.3 30.3 22.4 19.3 54.5 31.5 36.7 73.2 8.2 37.5 21.0 34.1 25.0 107.7 29.1 60.2 59.0 18.2 36.1 59.4 38.5 20.8 28.4 13.1 30.5 30.0 29.9 30.2 21.6 26.4 52.6 41.0 49.1 60.5 38.3 45.7 61.9 57.3 26.3 42.8 48.5 62.6 53.4 74.1 78.7 49.1 32.9 41.6 56.8 61.9 SULF1 "hSulf-1, KIAA1077, SULF-1" ENSG00000137573 "Sulfatase 1" Q8IWU6 8 69466624-69660915 "Predicted intracellular proteins" Apoptosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 180.3" "Cell type enhanced" "Detected in many" "Early spermatids: 214.2;Fibroblasts: 52.8;Inhibitory neurons: 63.0;Late spermatids: 101.4;Muller glia cells: 162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 315.4;BJ hTERT+: 420.2;fHDF/TERT166: 520.0;U-2197: 126.1;WM-115: 175.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054728 Supported "Intracellular and membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "HPA054728: AB_2682586" "unprognostic (2.89e-2)" "unprognostic (5.07e-2)" "unprognostic (3.87e-2)" "unprognostic (5.30e-2)" "unprognostic (3.60e-2)" "unprognostic (7.62e-2)" "unprognostic (3.77e-2)" "unprognostic (2.93e-2)" "unprognostic (3.58e-1)" "unprognostic (1.45e-1)" "unprognostic (3.69e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (8.91e-3)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (2.69e-2)" 24.1 2.6 8.1 24.4 6.4 0.0 8.0 2.2 2.7 14.5 180.3 36.4 10.0 28.7 14.2 18.3 11.3 30.6 14.2 6.4 7.4 9.9 1.8 9.7 6.3 1.9 18.2 14.2 3.5 1.4 9.7 4.2 5.8 50.8 20.6 60.0 4.3 41.9 2.2 2.6 14.1 72.6 3.4 2.2 4.0 2.2 18.6 2.2 19.9 11.2 4.8 32.1 9.5 3.0 0.0 0.0 57.3 0.0 6.2 27.3 0.4 315.4 420.2 10.9 1.7 0.0 1.2 0.5 0.2 520.0 0.0 0.4 0.8 0.5 2.1 0.0 1.1 0.0 1.0 0.0 1.5 0.1 0.5 35.6 3.7 18.2 6.7 15.2 1.4 0.0 0.0 0.6 8.5 1.3 0.0 0.0 6.5 0.0 0.4 0.0 23.2 0.9 0.0 0.0 1.1 0.0 0.0 0.5 0.0 22.6 76.7 0.0 0.0 29.0 0.8 126.1 0.0 0.1 0.0 0.1 0.1 0.1 175.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 6.4 2.2 2.7 6.4 7.4 1.9 18.2 5.8 3.4 18.6 3.0 10.6 9.6 6.2 3.9 0.1 0.9 2.7 7.8 26.2 1.8 1.3 13.7 4.3 2.8 13.5 5.5 0.0 0.3 0.0 0.0 0.0 0.3 214.2 1.0 30.5 13.5 1.2 2.7 9.6 0.0 0.0 52.8 0.0 1.0 0.0 0.1 15.4 0.5 0.3 0.0 63.0 0.3 0.0 0.6 1.3 101.4 6.5 0.8 0.0 1.0 0.0 162.8 0.0 3.5 0.6 0.7 0.1 1.9 0.0 1.4 0.0 0.1 5.5 6.5 0.0 5.2 42.4 1.6 1.4 2.5 0.3 0.3 0.3 0.1 0.0 0.4 SULF2 "HSULF-2, KIAA1247, SULF-2" ENSG00000196562 "Sulfatase 2" Q8IWU5 20 47656348-47786616 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 205.8;Oligodendrocyte precursor cells: 247.8;Theca cells: 265.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "basophil: 27.2;classical monocyte: 19.6;intermediate monocyte: 17.2;myeloid DC: 21.3;neutrophil: 31.5;non-classical monocyte: 9.0;plasmacytoid DC: 27.1" "Group enriched" "Detected in many" 84 "dendritic cells: 27.1;granulocytes: 31.5;monocytes: 19.6" "Cell line enhanced" "Detected in many" "EFO-21: 338.0;HaCaT: 230.1;HBEC3-KT: 259.4;hTCEpi: 815.1;MCF7: 695.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002325 Approved "Intracellular and membrane" NA NA 340000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "HPA002325: AB_1080126" "unprognostic (4.06e-2)" "prognostic unfavorable (6.43e-5)" "unprognostic (4.39e-1)" "unprognostic (8.99e-2)" "unprognostic (2.65e-1)" "unprognostic (9.08e-2)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" "unprognostic (1.81e-2)" "unprognostic (3.04e-2)" "unprognostic (1.53e-3)" "unprognostic (1.85e-1)" "prognostic unfavorable (4.02e-4)" "unprognostic (7.83e-2)" "unprognostic (1.14e-1)" "unprognostic (1.09e-1)" "unprognostic (7.14e-3)" 57.5 12.4 25.8 42.7 30.3 11.5 43.5 21.0 30.7 113.3 20.5 48.0 29.4 152.6 9.8 77.5 73.5 64.3 35.6 45.8 41.4 57.2 38.7 16.5 27.8 56.8 51.1 139.3 9.8 7.1 40.4 26.3 57.1 23.3 43.9 13.6 34.0 22.4 14.7 32.7 26.9 86.5 22.3 15.1 20.6 21.3 30.1 18.2 42.7 22.5 25.1 36.6 62.6 22.6 0.5 20.6 93.4 0.1 19.2 2.3 8.5 16.3 0.0 1.7 2.9 36.7 48.7 3.7 338.0 17.0 5.5 230.1 27.2 259.4 0.7 0.4 20.0 0.0 24.2 82.7 17.4 0.1 4.9 104.1 815.1 1.7 11.2 0.2 18.4 0.0 0.0 151.5 1.9 695.2 0.0 1.4 18.8 0.0 209.0 0.2 0.2 39.8 198.6 1.1 8.2 2.1 32.9 0.3 0.1 122.1 1.3 2.6 17.8 0.0 2.1 0.2 22.5 5.4 1.7 1.6 0.4 0.1 2.8 27.2 19.6 2.2 0.0 17.2 0.2 0.3 0.0 0.1 21.3 0.2 0.0 0.0 31.5 0.1 9.0 27.1 0.0 6.2 25.8 30.3 21.0 30.7 45.8 41.4 56.8 51.1 57.1 22.3 30.1 22.6 62.7 9.6 7.2 2.0 21.9 10.5 7.6 25.4 18.8 8.5 14.0 8.3 8.6 20.0 9.0 16.5 0.0 12.0 34.9 38.4 0.0 5.3 2.7 19.7 205.8 59.2 27.4 7.8 10.3 2.2 10.1 37.0 10.2 30.6 1.3 28.1 62.2 19.0 5.2 35.3 10.8 7.6 16.2 20.6 46.2 6.7 28.9 44.4 10.6 12.2 85.8 8.8 6.2 247.8 1.1 4.9 62.0 76.3 6.2 9.9 3.5 14.1 2.7 6.2 0.0 4.1 13.7 1.2 3.5 24.7 8.4 16.4 11.2 265.0 25.8 12.3 SUMF1 "FGE, UNQ3037" ENSG00000144455 "Sulfatase modifying factor 1" Q8NBK3 3 3700814-4467273 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 116.4;hTERT-RPE1: 117.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038025 Uncertain "Intracellular and membrane" NA NA 2800000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA038025: AB_10675624" "unprognostic (5.02e-2)" "unprognostic (2.30e-1)" "unprognostic (1.08e-1)" "unprognostic (8.99e-3)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (8.34e-3)" "unprognostic (3.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (2.65e-2)" "unprognostic (2.28e-1)" "prognostic favorable (4.79e-7)" "unprognostic (5.12e-2)" "unprognostic (2.58e-1)" "unprognostic (1.45e-1)" "unprognostic (7.86e-2)" 20.7 19.5 10.4 13.1 12.0 10.2 29.2 10.9 12.2 21.3 15.6 23.9 13.3 15.8 26.8 28.7 25.6 19.7 12.5 10.2 12.2 39.3 27.4 23.0 12.6 12.2 11.7 17.4 18.9 46.8 14.5 18.8 11.4 22.1 29.6 3.4 22.8 17.7 4.3 20.3 14.1 20.5 11.4 16.8 23.8 5.1 13.1 10.6 28.4 7.6 13.4 20.0 18.5 13.1 25.0 20.6 11.4 6.3 116.4 61.3 21.9 34.4 53.9 16.2 18.2 9.6 78.9 3.7 20.3 63.0 24.3 13.3 5.0 39.0 25.2 12.0 10.1 5.4 18.9 26.2 30.0 6.1 14.4 56.6 43.2 18.2 5.3 117.9 44.8 8.9 9.1 8.4 45.8 40.2 3.4 9.1 12.0 22.8 23.4 6.3 17.0 16.0 86.6 28.0 2.2 12.6 24.6 56.8 20.4 19.5 75.7 15.6 41.4 32.5 4.2 25.3 21.0 10.4 22.8 1.7 63.2 13.5 24.7 66.1 100.5 35.6 38.9 81.8 35.2 26.6 31.2 32.9 86.6 30.7 39.4 32.0 36.2 42.0 78.2 45.9 16.9 90.2 10.4 12.0 10.9 12.2 10.2 12.2 12.2 11.7 11.4 11.4 13.1 13.1 12.8 19.2 20.1 36.9 13.8 12.7 18.8 32.9 21.1 5.6 29.5 23.2 5.5 18.6 16.7 38.6 6.2 29.8 9.7 16.5 11.7 39.3 26.1 14.2 14.1 13.7 8.4 11.1 53.2 19.1 23.3 25.8 21.4 21.9 17.1 10.4 17.5 18.7 28.2 3.3 57.0 19.7 4.1 37.1 12.0 10.7 16.4 24.3 19.6 62.8 43.9 6.8 11.3 56.8 85.5 14.0 16.4 17.3 11.5 13.7 10.5 23.8 19.4 6.2 6.6 21.2 16.5 4.8 5.1 25.9 11.8 24.4 11.6 11.1 25.6 18.3 SUMF2 DKFZp566I1024 ENSG00000129103 "Sulfatase modifying factor 2" Q8NBJ7 7 56064002-56080670 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA024040, CAB025743, HPA074892" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Yes No 750000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "CAB025743: , HPA024040: AB_1857651, HPA074892: " "unprognostic (2.93e-1)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.42e-2)" "prognostic favorable (3.96e-4)" "unprognostic (3.87e-2)" "unprognostic (9.11e-3)" "unprognostic (1.69e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (7.20e-2)" "unprognostic (1.92e-1)" "unprognostic (7.26e-2)" "unprognostic (1.74e-1)" "unprognostic (1.74e-2)" "unprognostic (2.64e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.71e-4)" 64.1 64.6 26.1 43.0 29.7 51.5 57.5 29.3 27.1 91.3 45.0 67.4 89.2 57.5 64.8 46.8 102.6 70.6 30.8 25.1 27.8 93.4 94.8 71.6 50.2 35.2 29.6 59.7 91.8 115.8 31.8 45.5 33.4 79.3 69.1 11.0 69.5 77.1 22.4 47.5 74.4 57.7 29.9 57.0 92.7 23.7 30.8 57.6 91.2 21.4 51.3 57.2 43.6 35.9 352.3 102.9 46.0 211.8 214.4 147.5 68.9 114.5 156.1 92.6 114.5 57.2 278.0 57.1 96.5 162.4 90.4 172.3 27.4 131.3 61.1 90.6 42.9 36.4 63.5 54.2 138.4 89.7 108.7 116.8 124.5 83.7 143.3 186.9 137.7 101.4 116.4 236.6 151.3 76.8 77.2 115.7 63.5 272.0 52.2 61.5 45.4 359.0 127.7 39.1 54.0 65.6 142.4 294.2 140.9 98.9 294.5 144.5 115.2 85.6 121.1 211.1 98.6 160.8 130.8 84.0 139.7 165.7 283.2 58.1 60.3 22.0 71.1 80.5 90.9 59.8 70.9 71.8 72.3 49.1 75.3 75.2 4.4 49.0 90.3 132.6 82.7 90.2 26.1 29.7 29.3 27.1 25.1 27.8 35.2 29.6 33.4 29.9 30.8 35.9 44.0 57.7 30.5 20.5 47.3 33.8 44.1 46.1 39.9 25.7 57.9 25.4 10.4 87.2 31.0 90.1 14.6 44.5 85.3 45.1 19.6 95.3 3.8 93.1 70.2 43.7 59.3 41.7 21.2 55.7 96.7 54.7 55.5 78.9 54.5 47.0 51.0 91.3 68.1 43.7 24.4 61.8 22.4 79.8 38.7 8.0 69.6 50.4 53.4 14.0 73.0 23.8 70.0 10.6 24.2 48.4 64.6 47.4 65.0 50.7 91.8 45.6 34.5 13.5 52.6 41.6 44.1 31.6 28.6 52.8 41.9 46.7 52.7 58.7 85.8 42.7 SUPV3L1 SUV3 ENSG00000156502 "Suv3 like RNA helicase" Q8IYB8 10 69180234-69209099 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038380, HPA038405" Supported Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA038380: AB_2675983, HPA038405: AB_10675797" "unprognostic (4.70e-2)" "unprognostic (1.85e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-2)" "unprognostic (3.74e-2)" "unprognostic (3.32e-2)" "unprognostic (1.44e-2)" "unprognostic (1.78e-1)" "unprognostic (1.57e-1)" "unprognostic (9.47e-3)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (5.48e-3)" "unprognostic (5.03e-2)" "unprognostic (1.61e-1)" "unprognostic (5.27e-2)" "unprognostic (1.33e-1)" 10.1 10.9 7.9 8.7 8.2 24.2 11.5 10.2 10.3 7.7 7.6 11.6 8.9 9.3 7.9 8.8 8.3 6.0 15.8 8.5 8.2 12.9 17.9 6.1 12.0 7.9 7.4 10.6 9.3 16.5 7.5 8.7 7.9 8.0 12.7 11.1 8.9 8.6 25.9 10.6 8.6 9.3 7.2 9.9 8.9 15.8 7.8 11.0 10.9 29.1 12.2 9.5 7.7 8.5 28.9 19.9 17.4 53.5 19.1 16.1 22.7 17.5 27.1 34.7 32.6 51.4 23.8 51.5 14.0 17.6 24.8 32.3 42.2 27.4 33.1 21.5 33.1 22.6 14.9 27.2 48.1 54.3 16.5 20.5 33.7 31.9 72.6 23.6 20.3 32.2 59.6 26.1 19.2 18.7 33.1 33.5 20.8 27.2 106.7 30.1 24.7 22.6 15.6 13.9 24.7 18.7 24.2 49.7 46.7 19.1 15.5 23.5 12.7 13.7 24.7 21.1 34.3 20.5 25.4 47.5 22.6 56.4 8.9 8.9 5.1 4.7 11.1 7.3 12.5 9.0 7.9 9.5 7.1 7.3 8.7 9.6 0.9 7.7 5.4 3.9 8.8 6.2 7.9 8.2 10.2 10.3 8.5 8.2 7.9 7.4 7.9 7.2 7.8 8.5 11.2 6.4 7.4 15.3 21.7 23.8 11.6 16.6 21.6 21.6 10.8 9.5 22.5 5.7 15.1 7.3 4.2 17.8 49.3 11.7 11.7 11.6 13.4 17.2 17.6 10.1 9.0 10.3 29.6 8.6 11.4 12.6 14.8 28.8 7.6 15.1 5.7 12.0 9.6 11.8 28.2 9.0 16.2 6.0 10.0 4.5 6.8 9.4 5.4 15.0 7.2 11.3 19.6 14.1 17.6 8.5 8.1 9.1 37.0 10.8 8.5 14.3 12.6 12.5 6.6 17.2 14.6 38.6 26.6 23.6 22.3 22.4 28.8 16.1 14.1 10.7 SUSD1 DKFZP761E1824 ENSG00000106868 "Sushi domain containing 1" Q6UWL2 9 112040783-112175297 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 25.2;Kupffer cells: 31.2;NK-cells: 25.7;Oligodendrocyte precursor cells: 38.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "eosinophil: 11.0;plasmacytoid DC: 44.2" "Group enriched" "Detected in many" 5 "dendritic cells: 44.2;granulocytes: 11.0" "Cell line enhanced" "Detected in many" "HDLM-2: 50.7;HEL: 56.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048554 Approved Approved Nucleoplasm "Intracellular and membrane" NA NA 2300000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA048554: AB_2680439" "unprognostic (2.25e-1)" "unprognostic (4.02e-2)" "unprognostic (1.42e-2)" "unprognostic (1.62e-1)" "unprognostic (9.29e-3)" "unprognostic (5.27e-2)" "unprognostic (1.69e-2)" "unprognostic (3.73e-2)" "unprognostic (1.23e-2)" "unprognostic (1.29e-3)" "unprognostic (2.67e-1)" "unprognostic (3.31e-1)" "prognostic favorable (3.63e-6)" "unprognostic (2.14e-3)" "unprognostic (8.38e-2)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" 7.9 8.9 3.2 8.7 3.8 14.1 4.5 0.1 4.8 5.8 2.2 8.9 7.3 3.3 3.6 2.6 4.1 6.5 5.8 3.3 9.1 12.1 3.4 9.6 8.6 3.0 7.5 1.2 4.0 9.0 4.0 15.3 8.0 4.7 9.4 3.2 5.3 5.3 1.4 1.8 8.6 8.0 3.1 8.2 10.5 4.7 7.3 5.9 4.1 2.1 5.9 12.0 2.2 2.8 2.8 18.7 12.9 0.0 9.4 6.2 41.1 11.8 15.8 16.3 20.8 37.3 24.5 0.3 13.0 20.7 1.1 8.4 4.7 2.1 12.1 50.7 3.9 56.3 13.0 25.7 11.4 14.9 17.4 7.8 1.7 9.0 0.3 11.1 38.9 8.1 31.5 2.3 10.4 3.5 2.1 9.2 4.2 46.1 3.0 12.6 3.0 0.0 3.9 9.7 4.5 10.8 6.5 1.4 0.1 7.1 2.2 16.2 29.7 0.3 6.0 1.8 0.1 0.7 0.7 1.0 11.1 5.8 3.6 6.1 2.4 11.0 2.7 2.9 0.8 0.1 0.7 1.9 1.7 0.3 0.3 1.9 0.9 3.1 5.3 44.2 0.2 2.0 3.2 3.8 0.1 4.8 3.3 9.1 3.0 7.5 8.0 3.1 7.3 2.8 3.1 0.0 4.8 1.6 3.4 0.5 1.7 1.6 0.0 0.3 2.4 1.0 2.0 1.5 4.5 12.9 0.0 9.0 24.3 7.0 0.0 7.0 1.8 6.0 5.4 2.9 4.2 3.0 25.2 7.1 10.5 5.0 8.6 7.8 5.7 4.5 7.1 0.4 16.3 0.0 21.9 4.3 2.0 31.2 6.0 1.8 0.0 21.5 0.0 13.1 19.8 0.3 25.7 38.2 1.2 11.1 3.4 1.9 1.4 2.6 2.7 2.9 5.3 1.4 0.0 4.0 3.9 0.5 0.4 1.8 0.9 8.6 6.1 1.2 6.4 9.5 SUSD5 KIAA0527 ENSG00000173705 "Sushi domain containing 5" O60279 3 33150043-33218810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Excitatory neurons: 15.4;Inhibitory neurons: 10.5;Oligodendrocyte precursor cells: 61.3;Sertoli cells: 32.9;Smooth muscle cells: 29.0" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 31.1;HUVEC TERT2: 78.5;LHCN-M2: 30.4;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052788 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA 17000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "HPA052788: AB_2681948" "unprognostic (1.81e-1)" "unprognostic (1.52e-2)" "unprognostic (5.84e-3)" "unprognostic (5.52e-3)" "unprognostic (1.39e-3)" "unprognostic (4.05e-2)" "unprognostic (3.72e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" "unprognostic (2.24e-2)" "unprognostic (1.69e-1)" "unprognostic (2.15e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-3)" "unprognostic (6.45e-2)" "unprognostic (8.46e-2)" "unprognostic (1.89e-2)" 4.6 1.4 2.9 0.9 3.0 0.1 1.9 2.2 4.6 6.3 4.4 1.7 0.8 4.6 2.2 1.3 5.2 5.5 1.5 3.1 4.4 1.5 0.5 1.7 2.3 3.4 3.4 3.8 0.6 1.0 0.8 0.2 3.4 1.3 1.2 0.6 0.7 6.3 1.6 1.9 1.9 4.8 3.8 2.5 1.8 2.1 4.7 0.1 3.2 3.3 5.3 1.5 2.4 3.5 0.0 1.1 1.2 0.7 1.7 0.2 0.1 9.6 3.4 31.1 10.5 0.1 0.0 0.0 8.8 2.5 9.5 0.1 13.7 4.5 12.9 0.3 15.3 0.0 2.0 0.0 0.2 0.1 0.1 1.3 2.4 19.9 3.9 15.2 78.5 0.0 0.0 0.1 30.4 0.0 0.0 0.1 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.0 1.0 0.1 0.1 2.5 0.7 1.8 1.9 31.3 0.0 14.4 1.2 4.7 0.0 0.7 0.0 0.3 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.9 3.0 2.2 4.6 3.1 4.4 3.4 3.4 3.4 3.8 4.7 3.5 0.1 0.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 2.2 0.5 0.0 0.0 15.4 0.0 0.1 1.4 0.0 0.9 0.0 0.2 0.4 0.0 0.0 3.3 10.5 0.0 0.0 2.1 2.0 0.3 0.0 0.1 1.8 0.0 0.0 0.5 0.0 61.3 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 32.9 3.6 29.0 0.1 2.6 0.1 1.0 0.0 0.2 0.1 0.0 0.1 SVEP1 "bA427L11.3, C9orf13, FLJ13529, POLYDOM" ENSG00000165124 "Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1" Q4LDE5 9 110365248-110579880 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 38.6;placenta: 61.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 92.8;Inhibitory neurons: 50.3;Leydig cells: 42.0;Oligodendrocytes: 140.5;Syncytiotrophoblasts: 67.3;Theca cells: 34.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "ASC diff: 147.1;ASC TERT1: 84.7;BJ hTERT+: 62.3;HHSteC: 53.8;HSkMC: 66.7" "Region enhanced" "Detected in some" "cerebellum: 2.8" "Region enriched" "Detected in all" 5 "cerebellum: 20.8" "HPA020610, HPA021520" Enhanced "Intracellular and membrane" NA NA 160000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA020610: AB_2197021, HPA021520: AB_1855533" "unprognostic (4.47e-2)" "unprognostic (6.01e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.62e-2)" "unprognostic (9.13e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (3.31e-3)" "unprognostic (2.25e-1)" "unprognostic (1.51e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (9.84e-2)" "unprognostic (2.21e-1)" "unprognostic (1.55e-3)" 38.6 4.2 1.5 2.5 8.6 0.0 23.2 8.9 2.8 10.6 0.9 9.7 1.2 8.6 5.6 3.5 12.4 6.2 6.5 1.1 3.4 3.9 2.9 19.7 3.8 2.7 5.3 3.9 4.7 5.3 0.8 61.7 3.3 1.7 5.1 0.0 4.1 2.1 4.4 11.3 8.7 9.5 1.0 5.2 7.7 1.0 4.3 1.8 7.4 5.5 2.4 9.7 12.1 6.1 0.0 0.1 1.2 0.0 147.1 84.7 0.0 16.3 62.3 1.2 1.9 1.5 0.0 0.0 0.0 3.9 0.1 0.0 0.0 12.2 1.0 0.0 0.3 0.1 1.4 0.0 53.8 0.0 2.9 66.7 0.0 12.1 3.2 1.4 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.2 7.5 2.0 0.0 10.6 0.0 0.0 0.0 2.3 0.0 1.0 0.0 1.3 2.5 0.0 7.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 8.6 8.9 2.8 1.1 3.4 2.7 5.3 3.3 1.0 4.3 6.1 7.4 0.0 0.5 2.9 0.1 5.7 0.6 0.5 1.2 0.5 0.4 0.9 1.8 5.7 0.1 0.0 0.0 12.2 0.3 0.0 0.0 0.9 0.3 0.5 13.8 2.0 0.0 0.0 16.9 0.2 1.6 92.8 4.1 0.3 0.0 0.0 2.2 0.0 3.0 0.0 50.3 0.0 0.0 0.0 8.2 0.6 42.0 0.6 7.2 13.1 0.0 0.0 0.0 3.0 140.5 0.0 1.2 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 3.5 7.8 0.4 1.5 0.4 3.3 67.3 1.2 34.1 0.2 0.2 SWI5 "bA395P17.9, C9orf119, SAE3" ENSG00000175854 "SWI5 homologous recombination repair protein" 9 128275379-128316123 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 142.5" "Group enriched" "Detected in all" 9 "Early spermatids: 1180.8;Late spermatids: 1131.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052032 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA052032: AB_2681702" "unprognostic (1.27e-2)" "unprognostic (1.74e-2)" "unprognostic (3.56e-3)" "unprognostic (3.21e-2)" "unprognostic (1.42e-3)" "unprognostic (3.28e-2)" "prognostic unfavorable (6.78e-4)" "unprognostic (2.11e-1)" "unprognostic (1.19e-1)" "unprognostic (1.81e-1)" "unprognostic (4.58e-3)" "unprognostic (1.15e-1)" "prognostic favorable (9.39e-4)" "unprognostic (1.43e-1)" "unprognostic (6.73e-2)" "unprognostic (2.40e-1)" "unprognostic (7.38e-2)" 27.5 26.5 29.0 11.2 31.3 11.0 28.2 31.3 40.8 39.2 32.7 23.5 15.9 27.5 68.8 33.3 31.7 17.8 34.9 28.7 31.9 36.4 42.3 20.6 12.5 30.4 30.8 40.8 21.2 71.4 54.5 17.6 30.4 32.8 12.7 21.1 25.6 37.1 25.2 26.0 18.6 20.3 29.7 18.0 23.0 142.5 30.4 17.1 44.0 25.6 17.7 26.4 31.5 31.6 29.2 51.4 29.7 34.8 79.2 71.8 33.7 50.6 66.7 64.2 42.6 66.6 33.5 27.7 65.7 82.6 39.5 47.8 48.1 67.5 42.6 41.4 35.7 21.0 97.5 52.9 101.9 13.6 18.6 60.8 31.7 107.4 57.8 55.9 62.5 96.8 50.5 42.8 66.5 119.9 29.6 19.6 20.3 67.8 105.3 27.1 41.0 44.4 43.6 15.2 34.0 18.9 63.0 39.8 63.0 32.9 66.2 14.5 39.0 46.4 38.0 90.9 43.3 45.6 75.0 37.0 61.8 20.9 50.7 54.3 14.2 25.8 14.5 8.7 17.0 17.6 14.1 14.4 14.7 20.2 16.7 21.6 9.0 22.2 9.1 21.4 15.6 15.3 29.0 31.3 31.3 40.8 28.7 31.9 30.4 30.8 30.4 29.7 30.4 31.6 33.8 6.4 17.4 5.2 18.0 24.5 35.1 54.0 31.3 13.7 33.6 38.9 36.2 31.5 33.5 36.8 12.5 65.7 13.7 15.7 66.5 25.5 1180.8 30.7 29.1 31.3 25.6 17.2 2.9 38.5 41.1 40.7 19.9 30.7 9.5 27.9 35.7 82.4 33.2 1.7 3.3 27.5 28.5 20.8 13.0 1131.1 43.2 31.5 37.4 2.8 23.8 50.7 20.6 4.5 7.8 29.8 27.1 31.6 17.9 34.9 68.4 84.1 29.5 21.1 32.9 25.7 31.3 93.7 44.3 33.5 21.9 117.0 18.6 32.8 23.4 36.6 SWSAP1 "C19orf39, FLJ35119, SWS1AP1, ZSWIM7AP1" ENSG00000173928 "SWIM-type zinc finger 7 associated protein 1" Q6NVH7 19 11374666-11376951 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052712 Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 64: Macrophages - Immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA052712: AB_2681925" "unprognostic (6.45e-2)" "unprognostic (3.99e-2)" "unprognostic (1.48e-1)" "unprognostic (2.75e-1)" "unprognostic (1.92e-1)" "unprognostic (1.79e-2)" "unprognostic (5.03e-1)" "unprognostic (1.34e-2)" "unprognostic (4.65e-2)" "unprognostic (8.62e-3)" "unprognostic (1.40e-3)" "unprognostic (2.53e-1)" "unprognostic (1.34e-2)" "prognostic favorable (4.07e-4)" "unprognostic (1.61e-1)" "unprognostic (1.78e-1)" "unprognostic (4.18e-3)" 2.4 3.6 1.6 3.9 1.5 5.1 4.0 3.9 2.0 3.7 2.5 4.4 4.5 2.9 3.6 3.6 4.8 3.9 3.1 1.6 1.2 3.7 5.3 3.6 7.1 1.6 1.4 5.3 4.5 2.6 2.0 4.1 1.8 4.0 3.2 0.7 5.1 4.4 3.6 5.0 3.7 2.2 1.3 6.5 4.6 3.6 1.5 4.2 5.0 3.0 4.2 3.4 1.6 2.4 8.1 6.8 3.6 2.2 3.6 3.0 5.3 2.0 2.2 4.6 4.2 7.1 5.5 14.9 10.0 1.9 3.2 5.7 3.4 8.6 0.5 4.8 8.5 6.9 3.0 10.3 3.3 11.3 12.0 4.7 7.4 2.6 1.7 2.7 5.5 6.9 8.4 6.4 2.5 17.6 6.6 15.0 9.0 6.0 9.0 5.5 1.7 16.2 8.6 5.5 7.4 5.5 2.6 8.7 5.5 1.9 11.9 12.9 5.7 3.8 2.7 5.4 4.0 9.5 14.8 10.6 2.1 13.2 3.0 3.2 31.4 7.9 12.5 30.5 12.1 20.9 13.1 13.6 24.3 19.4 16.1 13.9 20.2 16.7 29.5 15.3 13.8 12.3 1.6 1.5 3.9 2.0 1.6 1.2 1.6 1.4 1.8 1.3 1.5 2.4 4.9 3.2 2.0 2.3 10.3 2.7 8.5 16.7 4.0 7.2 9.8 9.3 3.2 2.8 10.6 16.5 8.4 17.8 11.3 10.5 41.1 7.1 10.8 4.5 3.7 6.7 2.4 7.0 1.1 10.7 10.5 4.0 3.1 4.1 1.3 3.7 6.8 13.5 12.1 10.1 1.0 14.2 22.4 9.8 5.4 1.9 11.8 6.5 7.2 0.0 9.6 8.8 19.6 0.0 2.7 6.1 12.2 7.9 3.4 5.6 11.2 17.2 14.6 10.2 6.6 3.2 6.3 10.7 15.0 4.1 3.1 31.7 8.8 13.7 8.9 5.5 SYAP1 "FLJ14495, PRO3113" ENSG00000169895 "Synapse associated protein 1" Q96A49 X 16719612-16765340 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000175, HPA000882, HPA048047" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 13000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA000175: AB_1080142, HPA000882: AB_2666128, HPA048047: AB_2680240" "unprognostic (4.66e-2)" "unprognostic (2.99e-2)" "unprognostic (1.25e-2)" "unprognostic (5.44e-2)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (9.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.82e-1)" "unprognostic (1.62e-2)" "unprognostic (1.95e-1)" "unprognostic (3.95e-3)" "unprognostic (1.14e-2)" "unprognostic (8.10e-2)" "unprognostic (5.28e-3)" 15.3 25.1 5.8 11.2 6.5 25.5 12.4 7.1 7.8 13.1 11.8 14.6 17.4 9.2 8.7 11.3 11.1 13.2 9.5 6.8 7.4 16.0 29.4 9.1 10.3 7.1 6.7 10.9 11.8 15.5 7.6 8.7 7.0 12.8 13.0 7.8 10.7 8.0 12.6 10.3 15.6 9.9 6.6 7.1 13.2 6.4 7.7 7.9 11.5 7.6 10.7 10.8 8.3 8.8 29.2 24.1 17.0 32.0 22.6 25.6 7.8 22.7 16.2 18.6 18.4 22.8 23.5 22.6 32.4 22.3 37.9 16.9 21.0 29.7 24.7 14.8 41.9 9.0 25.4 21.9 16.2 15.5 13.4 17.6 13.7 32.2 27.1 21.5 26.0 6.9 19.8 12.2 25.4 34.2 8.4 16.6 19.9 16.1 26.3 9.1 21.5 22.8 27.8 18.9 17.3 21.3 42.2 29.7 23.1 22.0 39.5 13.8 20.6 23.7 12.5 48.7 18.6 13.4 12.2 26.1 23.3 7.7 19.8 7.4 7.2 9.3 9.9 7.9 8.1 9.0 8.4 9.2 7.8 7.0 8.3 8.7 12.0 10.1 11.4 6.5 10.5 6.5 5.8 6.5 7.1 7.8 6.8 7.4 7.1 6.7 7.0 6.6 7.7 8.8 60.4 64.1 75.6 14.4 96.0 64.1 107.0 69.5 37.0 20.2 116.0 78.2 74.3 88.6 92.2 79.1 22.9 66.5 273.8 164.3 111.6 119.6 214.8 219.3 84.7 53.3 106.1 45.9 13.9 132.1 83.3 65.5 72.4 176.3 210.0 38.3 71.4 216.0 49.5 23.5 16.0 107.4 63.1 70.8 241.0 296.2 42.3 171.5 67.6 8.4 55.7 49.4 64.9 11.6 26.9 183.6 159.2 54.5 185.5 80.3 148.3 164.3 169.7 21.5 59.2 56.9 68.1 15.3 21.5 42.0 52.6 150.5 156.6 48.5 118.6 104.4 SYCN "FLJ27441, INSSA1, SYL" ENSG00000179751 Syncollin Q0VAF6 19 39202825-39204263 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1004 "pancreas: 28361.5" "Cell type enriched" "Detected in some" 7 "Exocrine glandular cells: 4000.5" "Cancer enriched" "Detected in single" 842 "pancreatic cancer: 369.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047654 Enhanced "Intracellular and membrane" NA NA 920000 "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" "HPA047654: AB_2680112" "unprognostic (8.02e-2)" 4.5 0.8 0.0 0.4 0.0 0.0 2.5 0.0 0.1 2.6 0.0 0.9 4.0 0.9 0.2 1.5 0.6 0.0 4.5 0.0 0.0 1.0 3.0 0.5 0.6 0.0 0.0 11.2 28361.5 0.0 0.9 1.6 0.0 1.6 0.0 0.0 4.0 0.0 0.8 1.6 1.8 0.0 0.0 1.2 2.2 28.2 0.0 0.0 0.5 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 4.4 0.0 0.0 0.3 0.0 0.0 0.0 4000.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 1.2 0.5 0.0 0.0 9.8 0.0 0.0 0.0 0.0 506.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.6 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 SYNE1 "8B, ARCA1, C6orf98, CPG2, dJ45H2.2, enaptin, KIAA0796, MYNE1, Nesp1, Nesprin-1, SCAR8, SYNE-1B" ENSG00000131018 "Spectrin repeat containing nuclear envelope protein 1" Q8NF91 6 152121684-152637801 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" Actin-binding "Cancer-related genes, Disease variant, Emery-Dreifuss muscular dystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.5;choroid plexus: 182.9" "Cell type enhanced" "Detected in many" "Astrocytes: 550.1;Bipolar cells: 332.1;Excitatory neurons: 494.6;Inhibitory neurons: 482.6;Microglial cells: 315.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "eosinophil: 56.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 56.8" "Cell line enhanced" "Detected in many" "U-2 OS: 29.8;U-266/70: 29.1" "Low region specificity" "Detected in all" HPA019113 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA 72000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Nuclear membrane" "HPA019113: AB_1857707" "unprognostic (9.99e-2)" "unprognostic (1.91e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-1)" "unprognostic (2.28e-1)" "unprognostic (9.58e-3)" "unprognostic (1.11e-1)" "unprognostic (3.55e-3)" "unprognostic (1.58e-1)" "unprognostic (9.85e-2)" "unprognostic (8.87e-3)" "unprognostic (2.70e-1)" "unprognostic (4.14e-3)" "unprognostic (5.83e-2)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" 15.4 17.8 60.2 7.5 68.8 53.6 14.4 152.5 70.2 18.9 182.9 17.2 2.3 19.1 23.7 5.6 26.4 7.9 32.3 92.4 58.1 34.7 14.6 31.3 17.1 55.0 58.8 44.5 20.6 23.6 56.8 4.4 55.6 17.0 6.2 66.3 5.0 12.6 28.0 19.6 11.4 13.1 38.3 32.9 21.6 17.6 55.4 23.9 44.7 16.5 13.4 16.3 12.9 51.5 0.2 5.8 3.7 4.4 5.7 12.1 1.5 14.7 6.9 3.4 6.0 1.3 0.2 13.5 0.7 7.5 11.2 0.3 1.6 3.8 3.5 11.6 4.0 5.2 4.1 4.0 12.8 1.1 2.7 7.9 0.8 7.5 14.9 9.2 6.8 6.9 0.0 14.2 9.2 0.7 2.4 0.2 0.9 1.3 2.2 2.9 8.1 3.5 15.7 0.2 2.6 3.9 2.7 0.8 9.8 3.7 0.8 0.5 9.0 16.3 29.8 5.9 7.6 29.1 12.5 23.3 8.8 2.9 4.6 10.2 2.3 56.8 11.8 1.8 7.9 6.9 10.3 13.4 1.8 8.2 9.7 10.9 1.6 9.9 3.9 1.5 13.2 3.5 60.2 68.8 152.5 70.2 92.4 58.1 55.0 58.8 55.6 38.3 55.4 51.5 139.7 166.7 215.2 550.1 29.1 12.7 5.4 3.0 3.4 332.1 4.9 9.7 117.2 7.2 53.1 44.1 200.1 0.9 132.9 0.4 3.9 24.0 11.5 132.0 118.2 127.5 3.0 11.6 494.6 7.7 14.2 79.6 7.7 17.8 15.2 13.1 90.0 21.8 8.0 138.0 482.6 11.5 2.0 10.1 15.0 12.6 33.2 16.0 16.0 315.7 12.8 27.3 210.1 256.4 108.6 4.2 0.1 39.9 79.6 5.1 0.0 17.8 146.7 145.5 26.3 145.8 85.6 3.9 5.7 2.2 9.7 1.2 74.7 62.2 0.4 2.2 SYNGR2 ENSG00000108639 "Synaptogyrin 2" O43760 17 78168581-78173527 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 434.8;monocytes: 836.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 672.3;OE19: 547.9;SK-BR-3: 630.6;T-47d: 502.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014742 Approved Approved "Golgi apparatus" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus" "HPA014742: AB_2669079" "unprognostic (2.19e-2)" "unprognostic (1.05e-3)" "unprognostic (2.84e-1)" "unprognostic (6.77e-3)" "unprognostic (9.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-3)" "unprognostic (4.98e-2)" "unprognostic (1.26e-2)" "unprognostic (1.20e-2)" "unprognostic (9.44e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (4.74e-2)" "unprognostic (5.21e-2)" "unprognostic (3.51e-2)" "unprognostic (1.78e-2)" 92.9 59.7 50.9 99.4 74.0 112.9 105.5 75.1 63.5 59.2 53.5 118.0 86.4 56.7 22.6 133.8 75.5 70.7 150.1 51.5 61.2 113.0 101.0 158.1 143.9 88.1 70.7 45.3 188.9 52.9 91.2 61.7 86.0 130.7 71.1 2.8 184.8 45.6 369.9 161.4 125.4 33.2 67.3 148.1 141.7 31.8 68.0 68.2 68.7 122.6 112.6 92.0 87.9 92.5 172.5 334.5 9.0 73.9 3.2 1.1 52.5 58.6 60.2 55.0 31.4 200.9 173.6 136.9 123.2 33.5 47.8 245.5 39.9 95.0 16.2 97.2 177.2 47.0 46.9 140.8 76.1 77.3 356.5 3.4 105.1 17.5 47.2 77.9 118.7 50.4 193.9 672.3 5.3 337.4 77.3 79.6 24.4 547.9 140.1 44.3 19.2 391.4 166.7 155.5 53.8 60.2 48.6 630.6 60.3 31.7 502.8 122.2 31.7 1.1 54.2 28.1 77.8 280.7 109.7 79.8 39.7 52.8 9.5 694.4 656.1 237.9 173.6 944.7 202.1 970.0 231.0 200.2 907.6 972.1 204.6 168.6 282.5 219.8 1139.9 530.1 314.6 837.0 50.9 74.0 75.1 63.5 51.5 61.2 88.1 70.7 86.0 67.3 68.0 92.5 56.1 128.2 113.4 3.3 226.6 124.1 136.1 170.9 79.1 3.3 126.5 84.1 63.0 68.6 153.2 171.0 6.2 169.7 63.1 125.2 9.8 313.6 3.6 41.2 9.6 83.5 72.6 70.2 2.4 434.8 59.1 27.9 104.5 89.7 103.0 25.3 56.4 46.9 255.5 5.0 1.2 327.6 193.3 137.9 330.6 4.9 22.1 150.3 74.7 16.9 836.7 5.1 24.7 2.5 31.3 286.5 160.9 17.0 159.2 282.4 77.5 36.2 63.4 3.9 39.5 26.0 46.2 13.4 12.3 120.1 163.4 179.5 58.8 11.4 212.8 216.8 SYNGR4 ENSG00000105467 "Synaptogyrin 4" O95473 19 48364367-48376377 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 54.4" "Cell type enriched" "Detected in some" 4 "Spermatocytes: 159.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A549: 9.8;SCLC-21H: 24.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030075, HPA059286" Enhanced Approved "Golgi apparatus" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Golgi apparatus" "HPA030075: AB_10610559, HPA059286: AB_2683965" "unprognostic (1.58e-2)" "unprognostic (3.44e-2)" "unprognostic (3.18e-2)" "unprognostic (9.49e-4)" "unprognostic (2.51e-2)" "unprognostic (7.10e-2)" "unprognostic (2.52e-3)" "unprognostic (3.72e-3)" "unprognostic (2.87e-2)" "unprognostic (6.19e-2)" "unprognostic (6.69e-2)" "unprognostic (2.41e-2)" "unprognostic (2.02e-7)" "unprognostic (1.06e-2)" "unprognostic (1.74e-4)" "unprognostic (1.58e-1)" "unprognostic (9.77e-2)" 0.0 0.0 0.4 0.0 0.4 0.1 0.0 3.0 1.0 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.6 0.0 0.1 0.0 0.0 0.4 0.5 0.0 1.0 3.9 0.3 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.0 0.0 54.4 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 9.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.6 0.2 0.4 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.5 3.2 0.5 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 1.2 0.1 3.6 0.1 0.3 0.5 0.2 0.0 0.7 1.8 0.7 0.0 2.8 0.0 0.0 24.1 0.6 0.1 0.4 0.0 0.0 0.4 0.1 0.1 0.0 0.8 0.0 0.0 3.2 1.1 0.8 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 3.0 1.0 0.8 0.6 0.4 0.5 0.4 0.4 0.4 0.6 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 32.6 0.0 0.1 0.1 9.1 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.0 0.0 24.6 0.9 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.3 0.4 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.0 6.6 0.0 0.0 159.5 33.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 SYNJ2 INPP5H ENSG00000078269 "Synaptojanin 2" O15056 6 157981863-158099176 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 116.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 102.1;Glandular and luminal cells: 114.2;Oligodendrocytes: 502.1;Pancreatic endocrine cells: 140.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 133.4;TIME: 109.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031575 Approved Approved Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Microtubules Cytosol "HPA031575: AB_10604101" "prognostic unfavorable (2.63e-4)" "unprognostic (1.94e-2)" "unprognostic (7.61e-2)" "unprognostic (1.25e-2)" "unprognostic (1.48e-2)" "unprognostic (7.68e-2)" "unprognostic (1.24e-1)" "unprognostic (7.06e-2)" "unprognostic (2.91e-1)" "unprognostic (7.29e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.02e-6)" "unprognostic (1.66e-2)" "unprognostic (3.75e-2)" "unprognostic (1.75e-1)" "unprognostic (9.45e-2)" 4.2 5.8 26.1 6.2 69.9 20.0 8.0 58.6 42.0 4.5 1.9 10.6 7.1 7.6 10.5 7.7 5.5 9.4 10.7 22.5 32.4 8.4 4.9 4.5 5.9 98.1 74.7 3.6 8.1 1.5 4.1 3.5 78.9 6.9 10.4 2.3 16.5 5.8 7.2 4.3 6.8 7.7 57.8 4.2 8.5 9.4 58.2 6.5 5.2 9.5 6.5 11.0 4.6 116.2 16.4 56.6 4.5 7.3 3.4 11.2 24.2 29.8 60.4 35.0 41.1 28.7 13.5 0.5 19.8 57.9 133.4 15.4 10.1 18.5 40.1 22.9 9.3 31.8 29.8 30.9 6.5 10.9 32.6 5.9 9.9 53.3 12.4 47.1 61.7 16.4 24.7 6.5 16.1 7.6 14.0 12.2 5.1 51.4 31.2 6.0 19.1 13.4 11.8 18.8 34.8 2.0 22.7 14.2 5.9 17.2 10.9 7.1 109.7 25.8 26.8 61.4 36.5 2.5 7.8 0.4 49.2 17.5 18.4 3.0 0.6 0.5 0.9 0.3 1.9 1.0 1.3 0.8 0.6 2.0 1.1 0.8 4.3 1.0 0.4 0.5 1.2 0.5 26.1 69.9 58.6 42.0 22.5 32.4 98.1 74.7 78.9 57.8 58.2 116.2 17.2 3.2 3.3 5.2 15.4 21.7 19.9 7.5 14.2 2.4 25.4 18.4 13.9 21.5 8.6 18.4 0.0 7.7 12.8 20.0 3.9 59.0 35.5 48.5 13.7 26.4 17.4 5.5 102.1 35.2 5.0 16.6 34.1 114.2 5.1 37.7 7.9 5.2 2.0 0.0 10.1 14.8 10.2 2.2 17.6 56.5 1.2 12.5 10.6 7.5 6.9 1.6 16.5 8.5 502.1 140.2 7.1 6.4 13.5 50.6 13.1 1.7 14.4 0.6 0.0 7.3 18.9 0.9 1.1 11.5 17.2 15.9 17.1 2.2 15.7 36.2 SYNRG "AP1GBP1, MGC104959, SYNG" ENSG00000275066 "Synergin gamma" Q9UMZ2 17 37514807-37609472 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023554, HPA023555" Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA023554: AB_1844892, HPA023555: AB_2058337" "unprognostic (1.22e-1)" "unprognostic (1.24e-1)" "unprognostic (9.25e-2)" "unprognostic (1.11e-1)" "unprognostic (4.99e-2)" "unprognostic (3.44e-2)" "unprognostic (3.71e-2)" "unprognostic (1.90e-1)" "unprognostic (1.40e-1)" "unprognostic (1.15e-2)" "unprognostic (2.98e-2)" "unprognostic (2.21e-2)" "unprognostic (4.68e-3)" "unprognostic (8.76e-2)" "unprognostic (2.56e-1)" "unprognostic (2.91e-2)" "prognostic favorable (3.96e-4)" 8.3 9.1 4.5 12.9 6.6 6.7 7.7 5.6 7.0 8.4 7.1 8.7 6.8 7.6 10.8 9.6 7.5 8.1 5.7 4.1 7.4 9.9 8.5 8.8 21.4 6.7 7.5 8.3 8.8 11.9 11.7 7.7 7.4 8.0 9.5 9.2 9.1 6.7 7.1 8.5 12.1 6.9 6.2 16.6 10.4 13.0 6.8 24.2 9.8 6.0 19.3 8.5 8.4 7.5 7.9 13.1 18.0 12.0 12.0 11.5 7.6 12.3 12.4 13.2 15.1 12.5 11.8 15.5 11.4 11.3 13.5 8.0 15.8 6.5 19.7 14.0 9.1 8.9 8.2 6.0 14.0 14.0 19.2 13.1 14.9 15.5 8.8 12.4 18.3 26.3 18.0 13.3 14.3 6.4 29.4 7.3 7.9 7.3 4.8 19.1 15.3 10.5 12.3 15.4 14.2 13.4 11.5 3.7 10.8 20.5 10.5 11.0 17.4 9.6 12.3 8.0 11.5 14.9 18.5 24.4 10.9 7.1 10.7 12.4 4.0 8.8 12.5 2.9 16.4 10.9 10.9 12.5 3.4 10.9 10.7 10.6 8.3 17.5 3.2 13.2 11.8 4.4 4.5 6.6 5.6 7.0 4.1 7.4 6.7 7.5 7.4 6.2 6.8 7.5 26.9 54.5 38.7 37.5 64.8 8.5 14.6 17.2 19.9 49.8 22.6 21.2 26.3 20.0 25.1 33.1 54.2 18.5 77.0 24.1 17.6 24.7 43.7 26.4 29.7 28.1 42.6 17.9 36.5 21.8 10.6 20.4 26.0 31.8 25.9 23.5 22.9 23.2 21.8 37.0 42.5 22.4 18.3 40.9 24.7 50.1 22.7 27.2 16.0 40.3 30.4 31.2 108.1 55.3 71.3 26.4 19.6 24.0 67.6 17.5 23.5 29.7 23.4 49.5 13.1 29.3 20.2 65.8 23.9 19.0 9.2 26.5 81.8 21.7 17.1 20.8 SYT11 "DKFZp781D015, KIAA0080, MGC10881, MGC17226" ENSG00000132718 "Synaptotagmin 11" Q9BT88 1 155859567-155885199 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 148.8;retina: 68.6" "Group enriched" "Detected in many" 4 "Astrocytes: 91.1;Bipolar cells: 78.4;Excitatory neurons: 83.5;Horizontal cells: 89.2;Inhibitory neurons: 104.5;Muller glia cells: 135.6;Oligodendrocyte precursor cells: 113.1;Oligodendrocytes: 133.2" "Cancer enriched" "Detected in all" 12 "glioma: 117.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 184.0;SCLC-21H: 72.7;SH-SY5Y: 79.2;U-87 MG: 87.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064091 Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 5: Muller glia cells - Visual perception" "HPA064091: AB_2685189" "unprognostic (1.83e-1)" "unprognostic (5.99e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.93e-5)" "unprognostic (2.14e-1)" "unprognostic (8.02e-3)" "unprognostic (7.90e-2)" "unprognostic (4.43e-3)" "unprognostic (3.93e-1)" "unprognostic (1.16e-1)" "unprognostic (1.42e-2)" "unprognostic (9.65e-2)" "unprognostic (2.28e-2)" "unprognostic (1.66e-1)" "unprognostic (6.38e-2)" "unprognostic (1.10e-1)" "unprognostic (2.22e-3)" 8.0 19.7 94.1 8.8 113.2 3.8 5.0 112.8 126.8 14.0 3.8 13.9 3.4 17.3 11.9 5.4 8.6 11.3 13.4 105.2 106.7 5.1 1.7 7.9 11.1 107.0 108.8 13.4 3.1 1.6 37.1 9.8 107.7 11.8 6.6 68.6 2.4 16.4 2.5 2.4 6.7 19.4 113.2 10.2 6.1 5.7 124.7 3.0 3.5 5.4 9.2 10.6 9.4 148.8 0.1 0.7 47.2 1.1 33.6 17.9 0.2 8.9 24.1 9.3 16.7 0.1 1.3 9.4 3.9 32.2 14.3 0.6 4.0 0.1 13.9 46.0 0.9 9.1 1.3 0.1 9.6 5.1 26.9 11.2 0.0 33.7 0.6 52.5 30.2 0.3 0.1 184.0 12.8 0.1 0.5 2.5 30.8 0.0 0.2 1.9 4.7 0.2 1.5 0.0 72.7 79.2 1.3 0.1 11.1 0.9 0.1 1.3 22.6 17.4 10.8 11.9 11.4 48.7 25.4 18.8 87.2 0.1 13.6 6.1 4.9 0.1 16.9 5.9 4.7 1.9 8.8 11.8 7.0 1.5 0.8 8.8 2.5 7.8 8.5 0.4 17.2 8.3 94.1 113.2 112.8 126.8 105.2 106.7 107.0 108.8 107.7 113.2 124.7 148.8 25.3 0.0 0.0 91.1 3.2 0.5 0.2 0.2 0.6 78.4 0.5 0.9 11.4 0.0 0.1 1.8 22.9 0.1 23.3 0.0 0.0 1.4 0.1 0.9 12.0 20.3 4.8 3.4 83.5 1.0 0.2 9.3 2.0 1.9 12.0 16.0 7.1 0.4 4.7 89.2 104.5 0.1 0.0 9.4 5.2 0.7 2.8 11.2 3.6 23.4 13.6 135.6 19.6 113.1 133.2 1.4 0.0 15.8 5.5 0.4 0.1 1.2 1.0 13.7 19.7 7.7 15.9 2.0 1.0 0.1 1.0 0.0 14.3 2.1 0.0 0.3 SYT12 SRG1 ENSG00000173227 "Synaptotagmin 12" Q8IV01 11 67006778-67050863 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 22.5;liver: 17.6;parathyroid gland: 63.8" "Cell type enhanced" "Detected in many" "Astrocytes: 8.8;Basal respiratory cells: 10.9;Excitatory neurons: 39.3;Inhibitory neurons: 21.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HeLa: 49.8;MCF7: 38.0;SiHa: 44.3;SK-BR-3: 20.9;T-47d: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011006, HPA074255" Enhanced NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA011006: AB_2286996, HPA074255: " "unprognostic (2.72e-2)" "unprognostic (2.77e-2)" "unprognostic (2.23e-2)" "unprognostic (1.12e-3)" "unprognostic (4.47e-3)" "unprognostic (3.88e-2)" "unprognostic (1.20e-1)" "unprognostic (3.73e-2)" "unprognostic (2.04e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (4.13e-4)" "unprognostic (2.75e-1)" "unprognostic (9.86e-4)" "unprognostic (4.21e-2)" "unprognostic (7.38e-2)" "unprognostic (2.42e-2)" "unprognostic (9.85e-2)" 0.6 6.9 9.4 0.2 10.9 0.0 4.6 22.5 19.0 0.2 1.7 0.0 0.7 0.1 5.1 0.4 3.8 0.6 0.7 9.9 7.6 0.3 17.6 0.0 0.1 10.3 9.5 0.1 0.3 63.8 5.6 0.8 10.9 1.6 0.0 0.4 1.6 0.8 0.3 0.8 0.3 0.0 4.8 0.0 0.3 1.4 7.9 0.0 0.4 0.0 0.1 1.2 0.2 10.9 0.0 2.0 0.3 3.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 8.1 1.5 3.4 1.3 0.3 1.5 0.2 4.5 0.0 0.0 0.4 0.0 49.8 0.1 0.0 0.0 0.1 0.5 0.3 0.1 0.0 4.6 0.0 0.0 0.1 0.1 0.0 38.0 0.0 0.1 0.9 0.2 1.7 0.0 0.0 0.0 0.6 0.0 0.3 0.0 44.3 20.9 0.1 0.1 19.3 0.2 0.0 0.0 7.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 10.9 22.5 19.0 9.9 7.6 10.3 9.5 10.9 4.8 7.9 10.9 0.2 0.0 0.0 8.8 0.1 1.3 3.8 10.9 0.0 2.2 6.9 6.6 1.2 1.5 3.1 1.8 0.0 0.4 0.1 0.5 0.0 2.9 0.5 0.8 0.3 0.4 0.0 0.0 39.3 0.0 1.5 1.1 0.0 0.5 0.0 0.3 0.0 5.8 0.1 0.0 21.6 0.0 0.0 0.0 1.2 0.2 0.0 0.1 0.0 4.7 0.0 0.1 0.0 3.0 2.3 0.4 0.0 0.4 0.1 1.2 0.2 0.1 1.6 1.2 0.0 1.2 1.6 0.8 1.2 0.0 1.1 1.9 0.5 0.0 0.4 1.3 SYT4 "HsT1192, KIAA1342" ENSG00000132872 "Synaptotagmin 4" Q9H2B2 18 43267892-43277535 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.7;pituitary gland: 30.7;retina: 25.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 66.8;Cone photoreceptor cells: 22.9;Enteroendocrine cells: 28.7;Excitatory neurons: 50.9;Fibroblasts: 23.0;Inhibitory neurons: 34.1" "Group enriched" "Detected in some" 5 "glioma: 2.0;pancreatic cancer: 4.1;prostate cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 245.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010574 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "HPA010574: AB_2668309" "unprognostic (2.91e-3)" "unprognostic (2.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.87e-1)" "unprognostic (7.67e-3)" "unprognostic (5.30e-3)" "unprognostic (3.95e-2)" "unprognostic (1.23e-3)" "unprognostic (3.61e-1)" "unprognostic (3.80e-2)" 3.7 15.9 21.5 1.4 18.6 0.1 0.0 74.7 42.6 0.0 0.0 1.2 0.8 0.0 0.0 0.1 0.0 0.0 1.3 18.6 50.4 0.1 0.0 0.9 0.0 10.5 15.3 0.5 3.7 0.0 30.7 0.1 39.3 0.6 0.8 25.2 0.1 8.3 0.0 0.0 0.7 0.6 13.5 0.0 3.2 1.6 18.3 0.4 0.3 0.0 0.0 0.0 0.5 10.9 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 245.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 18.6 74.7 42.6 18.6 50.4 10.5 15.3 39.3 13.5 18.3 10.9 0.0 0.0 1.1 8.8 0.0 0.1 0.0 0.0 0.0 66.8 0.0 0.0 3.6 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 28.7 0.0 50.9 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 9.4 0.0 2.5 0.0 7.5 7.6 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.7 10.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.1 SYT7 "IPCA-7, MGC150517, PCANAP7, SYT-VII" ENSG00000011347 "Synaptotagmin 7" O43581 11 61513714-61581148 "Predicted intracellular proteins, Predicted membrane proteins" Exocytosis Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;liver: 86.7;salivary gland: 57.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.2;Enteroendocrine cells: 49.8;Excitatory neurons: 82.1;Hepatocytes: 70.7;Prostatic glandular cells: 36.8;Syncytiotrophoblasts: 66.4" "Cancer enhanced" "Detected in all" "prostate cancer: 54.4" "Region enhanced" "Detected in many" "cerebral cortex: 78.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 35.0;hTERT-HME1: 89.5;RT4: 37.8;SCLC-21H: 28.4;SK-BR-3: 40.7;T-47d: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012869 Enhanced NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA012869: AB_1857698" "unprognostic (7.09e-2)" "unprognostic (8.26e-2)" "unprognostic (2.43e-1)" "unprognostic (2.10e-2)" "unprognostic (5.42e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (4.37e-2)" "unprognostic (5.08e-2)" "unprognostic (2.74e-3)" "unprognostic (1.79e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (2.23e-3)" "unprognostic (2.47e-1)" 3.8 4.3 17.7 1.2 33.8 0.1 9.2 0.0 78.4 3.1 0.0 5.0 2.3 2.6 1.8 3.5 3.4 1.2 19.0 30.7 1.9 24.7 86.7 1.9 0.3 0.0 1.9 1.3 16.7 5.7 51.6 18.4 0.0 50.8 5.3 8.0 57.0 0.9 3.6 4.2 5.2 1.8 0.0 2.1 3.7 4.0 13.9 0.4 8.0 1.8 0.3 1.9 3.3 38.5 13.4 1.9 0.5 0.2 1.0 14.1 10.4 0.2 35.0 0.6 0.5 3.5 6.9 0.0 0.6 0.2 1.3 6.9 0.9 0.2 0.2 0.2 1.7 0.0 1.7 2.1 0.9 0.1 0.1 0.4 7.8 4.2 89.5 0.2 0.2 0.8 0.1 0.2 0.5 21.6 0.1 0.3 2.4 24.8 14.1 0.0 0.7 1.7 0.0 37.8 28.4 5.2 1.9 40.7 0.3 5.6 39.8 0.0 0.0 8.6 3.1 10.1 0.2 0.0 0.0 0.1 0.9 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 33.8 0.0 78.4 30.7 1.9 0.0 1.9 0.0 0.0 13.9 38.5 10.6 0.0 0.5 4.2 0.2 0.3 0.4 5.1 0.0 22.6 23.2 16.3 22.3 1.5 5.0 5.5 0.0 45.2 0.6 1.9 5.9 1.2 8.4 0.3 4.3 4.9 49.8 2.7 82.1 1.6 3.4 3.0 0.0 0.5 0.0 5.9 4.6 70.7 4.0 21.9 17.8 30.2 6.1 1.0 0.0 7.6 3.4 0.1 1.8 7.5 0.0 0.6 0.0 6.0 2.5 1.0 4.6 2.2 0.0 36.8 3.5 0.1 1.3 3.5 0.0 2.8 1.4 0.8 3.9 0.9 0.1 66.4 0.2 0.6 2.4 1.7 TAC1 "NKNA, NPK, TAC2" ENSG00000006128 "Tachykinin precursor 1" P20366 7 97732084-97740472 "Predicted secreted proteins" "Neuropeptide, Neurotransmitter" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 55.6;lymphoid tissue: 46.1" "Cell type enriched" "Detected in some" 7 "Inhibitory neurons: 99.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "U-266/70: 22.8" "Region enhanced" "Detected in all" "basal ganglia: 560.0" "Region enriched" "Detected in all" 10 "basal ganglia: 388.8" HPA014429 Enhanced "Secreted to blood" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA014429: AB_1857722" "unprognostic (9.24e-3)" "unprognostic (2.65e-2)" "unprognostic (1.84e-1)" "unprognostic (1.19e-1)" "unprognostic (1.92e-1)" "unprognostic (2.08e-1)" "unprognostic (7.95e-2)" "unprognostic (3.24e-1)" "unprognostic (1.70e-2)" "unprognostic (3.21e-2)" "unprognostic (1.70e-1)" "unprognostic (1.69e-1)" "unprognostic (3.86e-2)" 2.1 8.6 7.3 10.9 34.2 0.0 2.1 2.0 12.1 0.6 1.9 9.8 8.3 0.8 1.6 0.0 1.0 6.6 1.4 6.1 45.1 7.3 0.3 0.5 0.0 53.2 55.6 0.2 0.6 0.5 1.5 0.0 21.5 1.3 3.6 3.4 6.8 2.1 0.3 1.2 10.3 7.5 16.4 46.1 3.0 0.4 23.9 0.1 7.4 0.0 0.0 1.5 0.8 6.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 34.2 2.0 12.1 6.1 45.1 53.2 55.6 21.5 16.4 23.9 6.4 0.1 0.0 0.0 2.9 0.5 0.4 0.1 0.0 0.0 0.0 0.4 0.6 0.3 7.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 2.0 1.0 0.0 0.0 0.0 1.2 0.0 0.0 13.2 0.0 9.7 0.0 0.0 0.0 0.0 0.1 0.0 99.4 5.4 0.0 0.0 0.4 0.1 0.3 0.1 0.0 1.9 0.0 0.0 0.0 1.5 3.4 0.5 0.0 0.0 0.0 4.2 0.3 9.1 0.0 0.0 0.0 1.1 1.3 0.2 2.1 0.0 0.1 0.0 0.4 0.0 0.5 0.9 TAC3 "LncZBTB39, LncZBTB39-1:2, NK3, NKB, NKNB, ZNEUROK1" ENSG00000166863 "Tachykinin precursor 3" Q9UHF0 12 57010000-57028883 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "placenta: 431.7" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 13.9;Extravillous trophoblasts: 19.6;Inhibitory neurons: 40.0;Syncytiotrophoblasts: 18.3" "Cancer enriched" "Detected in many" 7 "urothelial cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "K-562: 14.4;SuSa: 13.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA045919 Supported Supported Approved Vesicles "Secreted in female reproductive system" NA NA 130000 "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA045919: AB_10960533" "unprognostic (4.53e-2)" "unprognostic (1.97e-2)" "unprognostic (8.41e-2)" "unprognostic (3.00e-2)" "unprognostic (3.61e-2)" "unprognostic (1.76e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "unprognostic (1.34e-1)" "unprognostic (2.03e-1)" "unprognostic (5.28e-2)" "unprognostic (4.71e-14)" "unprognostic (1.58e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" 0.1 0.3 15.2 2.5 11.0 1.0 0.1 5.2 16.5 0.1 5.6 3.8 3.0 0.3 0.0 0.1 0.0 0.3 0.1 11.2 25.1 0.1 0.1 0.1 0.2 16.8 7.7 0.2 0.6 0.0 0.7 431.7 7.7 0.2 1.5 6.1 0.0 0.0 0.2 0.5 6.5 4.8 27.3 0.1 13.1 1.8 6.2 0.5 0.1 0.0 0.4 3.1 0.3 9.8 0.0 0.1 0.0 0.4 0.0 0.0 1.2 0.0 1.1 0.3 0.0 1.6 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 14.4 0.3 0.0 0.0 0.0 0.2 1.6 0.5 0.0 0.0 0.0 0.0 0.0 1.5 2.1 0.6 0.0 0.8 0.0 13.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 11.0 5.2 16.5 11.2 25.1 16.8 7.7 7.7 27.3 6.2 9.8 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.0 13.9 0.0 1.4 0.0 0.0 0.1 0.0 0.4 0.1 1.2 2.7 0.5 0.0 19.6 2.6 0.0 0.1 0.0 4.3 0.7 0.0 2.2 0.0 40.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.5 2.8 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.4 2.6 1.0 0.0 0.0 18.3 0.0 0.0 1.8 0.0 TAC4 "HK-1, PPT-C, Pptc" ENSG00000176358 "Tachykinin precursor 4" Q86UU9 17 49838309-49848017 "Predicted secreted proteins" "Hypotensive agent" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 5.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Excitatory neurons: 2.3;Inhibitory neurons: 1.2;Oligodendrocyte precursor cells: 1.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.5;BEWO: 5.9;CACO-2: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.49e-2)" "unprognostic (8.14e-2)" "unprognostic (8.95e-2)" "unprognostic (1.71e-1)" "unprognostic (6.24e-2)" "unprognostic (8.15e-2)" "unprognostic (5.61e-2)" "unprognostic (6.05e-3)" "unprognostic (3.19e-1)" "unprognostic (2.00e-1)" "unprognostic (4.52e-2)" "unprognostic (4.69e-3)" "unprognostic (8.19e-5)" "unprognostic (8.69e-2)" "unprognostic (2.23e-1)" "unprognostic (7.98e-2)" "unprognostic (1.92e-1)" 0.2 0.3 0.5 0.3 0.4 0.7 0.1 1.7 1.1 0.2 0.8 0.1 0.2 0.2 0.0 0.6 0.0 0.3 1.1 0.4 0.0 0.1 1.7 0.3 0.4 0.3 0.1 0.1 0.1 0.1 5.0 0.2 0.2 0.3 0.0 0.3 0.4 0.0 0.2 1.7 0.2 0.3 0.0 0.7 0.3 0.3 0.0 0.0 0.5 0.0 0.0 0.4 0.1 0.3 0.0 2.5 0.0 0.4 0.0 0.0 5.9 0.0 0.0 0.0 0.0 3.5 0.2 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.4 0.7 0.1 0.4 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.2 0.3 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.3 0.0 0.5 0.2 0.1 0.1 0.2 0.6 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 1.7 1.1 0.4 0.0 0.3 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TAF10 "TAF2A, TAF2H, TAFII30" ENSG00000166337 "TATA-box binding protein associated factor 10" Q12962 11 6606294-6612539 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 361.8;Late spermatids: 1039.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004148, CAB022405" Supported Supported Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB022405: , HPA004148: AB_1857736" "unprognostic (1.69e-3)" "unprognostic (2.32e-1)" "unprognostic (3.19e-2)" "unprognostic (6.21e-3)" "unprognostic (9.10e-2)" "unprognostic (6.99e-2)" "unprognostic (5.24e-3)" "unprognostic (9.03e-3)" "unprognostic (1.12e-1)" "unprognostic (1.24e-2)" "unprognostic (3.46e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.38e-1)" "unprognostic (2.55e-1)" "unprognostic (9.64e-3)" "unprognostic (3.80e-3)" 78.9 140.7 147.5 53.3 150.3 93.0 69.2 149.2 204.1 59.3 142.6 66.2 44.3 63.6 97.5 103.1 61.7 28.3 130.0 147.7 156.2 100.9 151.6 76.7 56.8 157.1 153.2 50.0 152.8 53.2 96.2 31.0 155.9 79.8 54.1 30.8 69.6 42.9 107.5 61.2 68.1 38.7 147.7 125.4 100.1 190.7 149.9 82.0 74.6 50.0 76.3 72.1 58.3 150.9 82.4 138.2 88.7 77.7 140.6 135.1 67.5 61.4 134.6 98.9 98.6 102.0 145.0 45.4 77.2 111.4 137.4 68.6 66.0 99.7 97.3 92.2 95.3 64.2 95.6 122.2 227.7 85.4 98.9 157.8 125.1 77.5 163.0 168.0 110.6 139.5 67.0 80.7 157.4 159.5 122.2 78.5 62.6 130.9 107.6 72.2 46.8 78.5 163.5 108.1 62.2 84.4 82.9 95.0 107.6 129.8 67.1 100.6 64.6 67.2 78.9 97.6 87.9 94.6 70.7 73.4 110.4 44.5 108.2 12.7 9.9 11.8 9.7 15.7 8.8 9.8 9.4 11.1 10.8 11.6 8.8 7.8 27.9 8.7 16.2 23.7 11.4 5.1 147.5 150.3 149.2 204.1 147.7 156.2 157.1 153.2 155.9 147.7 149.9 150.9 106.4 3.2 23.3 6.2 60.1 21.4 56.8 9.4 32.5 23.0 116.3 148.0 51.5 47.1 13.1 36.8 20.9 48.5 130.7 79.7 19.6 18.2 361.8 93.8 90.0 39.3 34.7 45.4 4.4 33.3 55.2 43.0 56.6 86.3 5.1 70.5 26.7 53.8 65.9 23.5 4.4 50.8 2.0 78.4 44.4 1039.1 24.5 91.2 26.6 9.4 36.3 84.7 53.5 2.5 9.9 30.7 68.5 19.2 89.6 85.8 55.5 43.1 14.0 27.1 0.0 36.3 50.0 108.8 33.2 75.0 29.1 53.6 65.0 124.1 44.2 88.7 TAFA1 "FAM19A1, TAFA-1" ENSG00000183662 "TAFA chemokine like family member 1" Q7Z5A9 3 68004247-68545621 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 15.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in many" 6 "T-cells: 20.7" "Cell line enriched" "Detected in single" 10 "REH: 1.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 12.5;cerebral cortex: 35.6;hippocampal formation: 33.0" HPA013407 Approved "Secreted in brain" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "HPA013407: AB_1848386" "unprognostic (5.19e-2)" "unprognostic (4.64e-3)" "unprognostic (1.97e-2)" "unprognostic (1.86e-2)" "unprognostic (7.95e-2)" "unprognostic (6.40e-2)" "unprognostic (3.42e-3)" "unprognostic (1.79e-1)" "unprognostic (1.20e-1)" "unprognostic (2.41e-1)" "unprognostic (1.41e-2)" "unprognostic (7.87e-2)" "unprognostic (1.35e-3)" "unprognostic (2.11e-1)" "unprognostic (1.99e-1)" "unprognostic (3.50e-4)" "unprognostic (5.77e-2)" 0.2 1.1 4.1 0.3 7.3 0.0 0.0 0.0 13.9 0.0 1.6 0.2 1.3 0.2 1.1 0.1 0.0 0.7 0.1 13.9 9.1 0.3 0.3 0.1 0.6 12.4 1.0 0.0 0.0 0.0 0.4 0.0 15.4 1.4 0.1 0.3 0.1 3.8 0.1 0.0 0.2 0.3 0.4 0.4 0.1 0.2 8.6 0.0 0.1 0.2 0.2 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 20.7 0.0 15.9 0.0 16.6 11.1 0.0 0.0 11.9 15.9 0.4 3.7 0.0 0.1 8.4 3.3 4.1 7.3 0.0 13.9 13.9 9.1 12.4 1.0 15.4 0.4 8.6 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TAFA2 "FAM19A2, TAFA-2" ENSG00000198673 "TAFA chemokine like family member 2" Q8N3H0 12 61708259-62279150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 19.9;seminal vesicle: 7.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.7;Cytotrophoblasts: 1.3;Extravillous trophoblasts: 1.4;Hofbauer cells: 1.8;Plasma cells: 1.0;Syncytiotrophoblasts: 2.6" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "Region enhanced" "Detected in many" "cerebral cortex: 19.9" "Group enriched" "Detected in many" 4 "basophil: 31.6;neutrophil: 12.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 31.6" "Cell line enhanced" "Detected in some" "hTCEpi: 5.7;SCLC-21H: 2.1;WM-115: 4.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.89e-3)" "unprognostic (9.33e-2)" "unprognostic (1.02e-1)" "unprognostic (1.37e-2)" "unprognostic (2.78e-1)" "unprognostic (4.83e-1)" "unprognostic (6.62e-2)" "unprognostic (4.16e-3)" "unprognostic (4.08e-1)" "unprognostic (1.80e-1)" "unprognostic (3.22e-5)" "unprognostic (1.05e-1)" "unprognostic (2.22e-2)" "unprognostic (3.31e-2)" "unprognostic (1.01e-1)" "unprognostic (3.49e-2)" "unprognostic (1.28e-1)" 1.0 1.0 4.4 0.7 7.1 3.0 0.8 0.0 19.9 1.7 0.0 1.0 1.0 1.1 0.5 0.4 0.7 0.6 0.4 11.2 0.5 0.4 0.4 0.4 0.5 2.6 0.0 2.7 1.0 0.5 1.5 3.3 3.8 1.4 0.8 0.9 0.7 7.2 0.2 0.7 0.7 0.5 0.0 1.1 0.7 3.0 0.4 0.8 0.5 0.5 0.3 1.1 1.8 1.7 0.1 0.0 1.1 0.2 0.5 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.4 0.1 0.0 0.1 0.2 0.2 0.4 0.2 0.8 1.6 0.0 0.2 0.8 1.3 0.0 5.7 0.0 0.0 0.1 0.0 1.5 1.1 0.6 0.0 0.0 1.5 0.3 0.5 0.1 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.1 0.5 0.0 0.4 0.4 0.2 0.2 0.0 0.2 0.6 0.1 0.3 0.4 0.5 0.3 0.0 0.3 4.7 31.6 2.4 5.2 0.5 0.8 0.2 0.5 1.0 0.5 0.3 0.2 0.8 0.3 12.0 0.6 0.2 0.5 3.9 0.5 4.4 7.1 0.0 19.9 11.2 0.5 2.6 0.0 3.8 0.0 0.4 1.7 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.0 0.0 TAFA4 "FAM19A4, TAFA-4" ENSG00000163377 "TAFA chemokine like family member 4" Q96LR4 3 68731766-68953297 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "adrenal gland: 14.9;brain: 11.6;retina: 11.1;stomach 1: 4.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.8;NTERA-2: 9.2;SCLC-21H: 1.0;SuSa: 2.5" "Region enriched" "Detected in many" 5 "thalamus: 13.5" "Low region specificity" "Detected in many" "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "unprognostic (1.92e-1)" "unprognostic (9.97e-3)" "unprognostic (2.28e-1)" "unprognostic (8.19e-3)" "unprognostic (8.78e-2)" "unprognostic (2.00e-2)" "unprognostic (3.01e-2)" "unprognostic (1.22e-1)" "unprognostic (3.66e-2)" "unprognostic (8.06e-2)" "unprognostic (2.50e-1)" 0.0 14.9 4.8 0.2 5.0 0.0 0.0 3.8 3.0 0.0 0.4 0.4 0.0 0.0 0.0 0.2 0.0 1.2 0.0 1.4 7.9 0.1 0.0 0.1 0.0 4.5 9.4 0.4 0.0 0.0 0.7 0.3 4.3 0.9 0.0 11.1 0.0 0.1 0.0 0.0 0.2 0.2 3.2 0.0 4.9 1.0 11.6 0.0 0.0 0.0 0.0 0.1 0.0 7.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 5.0 3.8 3.0 1.4 7.9 4.5 9.4 4.3 3.2 11.6 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAFA5 "FAM19A5, TAFA-5" ENSG00000219438 "TAFA chemokine like family member 5" Q7Z5A7 22 48489553-48850912 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 85.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Fibroblasts: 1.1" "Cancer enhanced" "Detected in all" "glioma: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 17.3;HEK 293: 13.6;Hep G2: 32.1;NTERA-2: 12.7;U-2 OS: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025629 Approved "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB025629: " "unprognostic (2.86e-1)" "unprognostic (2.98e-1)" "unprognostic (3.42e-2)" "unprognostic (2.19e-1)" "unprognostic (3.57e-1)" "unprognostic (1.80e-1)" "unprognostic (2.82e-3)" "unprognostic (2.41e-2)" "unprognostic (6.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-2)" "unprognostic (1.26e-1)" "unprognostic (9.31e-3)" "unprognostic (2.64e-2)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.94e-2)" 2.7 1.3 50.3 0.8 40.6 0.0 2.0 37.0 51.8 19.7 15.0 8.4 1.0 8.1 4.7 0.9 5.2 2.0 2.5 53.9 43.0 2.4 2.7 2.1 0.4 55.2 85.9 12.1 2.4 4.3 7.0 0.1 51.1 6.8 0.2 3.6 4.9 3.2 1.5 5.4 3.3 0.7 41.5 0.3 2.9 3.3 49.6 1.2 0.8 1.7 0.1 4.0 4.9 28.2 0.0 1.3 2.5 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 17.3 0.1 0.1 1.3 0.0 0.0 0.0 13.6 0.0 0.2 32.1 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.1 0.3 12.7 0.6 0.0 0.6 0.0 7.4 0.0 0.0 7.2 0.2 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 21.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 40.6 37.0 51.8 53.9 43.0 55.2 85.9 51.1 41.5 49.6 28.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAGLN2 "HA1756, KIAA0120" ENSG00000158710 "Transgelin 2" P37802 1 159918107-159925507 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2404.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA001925 Approved Approved "Actin filaments,Cytosol" "Intracellular and membrane" NA NA 270000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Actin filaments" "HPA001925: AB_1857756" "prognostic unfavorable (2.06e-5)" "unprognostic (2.56e-1)" "unprognostic (4.05e-2)" "unprognostic (1.27e-1)" "unprognostic (3.69e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (7.07e-5)" "unprognostic (4.61e-2)" "unprognostic (1.50e-1)" "unprognostic (3.21e-1)" "unprognostic (3.56e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.92e-10)" "unprognostic (1.81e-1)" "unprognostic (9.22e-2)" "unprognostic (3.95e-2)" "unprognostic (2.50e-2)" 401.9 154.7 103.7 356.0 103.2 437.3 355.4 106.3 115.0 266.6 94.9 337.4 314.3 220.5 94.9 494.0 231.9 282.6 351.1 101.1 152.7 307.9 254.4 687.7 321.1 141.7 117.6 170.9 284.7 81.0 100.0 378.2 122.9 208.5 307.9 46.1 388.7 205.2 83.4 418.2 356.3 254.4 125.2 479.7 698.8 127.0 125.9 309.6 210.2 139.6 386.4 436.1 350.0 114.9 1382.3 723.7 22.3 8.3 266.8 646.6 835.4 760.0 872.6 1635.2 799.8 786.6 1049.3 862.0 628.0 954.9 495.0 1054.3 378.1 1039.9 978.8 974.3 355.5 1140.7 651.8 50.0 322.7 808.2 1221.4 667.4 776.9 1030.4 504.3 1134.7 1029.0 260.3 494.8 578.9 586.1 563.0 378.1 601.2 619.3 947.6 1457.7 2.9 391.7 1275.3 376.6 527.7 340.7 325.6 900.7 1435.1 410.3 1190.6 756.5 814.2 1147.3 955.1 1134.4 876.9 2078.0 230.8 110.6 525.0 1238.3 541.3 603.8 1458.4 742.0 3160.6 558.9 449.7 499.9 866.5 620.0 544.6 1177.7 680.2 321.6 360.3 3746.8 817.6 356.9 1966.4 756.1 2257.9 103.7 103.2 106.3 115.0 101.1 152.7 141.7 117.6 122.9 125.2 125.9 114.9 617.1 179.5 130.5 0.3 507.8 549.1 330.6 454.3 307.9 31.6 257.0 201.8 12.8 121.5 221.4 183.9 18.8 497.4 567.6 371.0 74.3 1273.4 54.3 289.4 145.9 509.6 317.8 197.6 0.1 1206.9 2404.5 405.2 545.3 242.7 418.8 32.0 265.2 64.1 443.7 3.3 0.6 445.5 284.8 285.9 952.4 85.9 118.7 651.5 334.4 16.9 911.4 66.3 186.4 0.5 1.6 877.4 263.2 63.9 393.4 337.5 324.2 208.2 275.9 25.6 184.1 358.3 324.3 14.3 20.7 494.1 572.5 230.4 393.6 136.7 271.7 405.9 TAP1 "ABCB2, D6S114E, PSF1, RING4" ENSG00000168394 "Transporter 1, ATP binding cassette subfamily B member" Q03518 6 32845209-32853816 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Peptide transport, Protein transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 126.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009516, HPA072354" Approved Approved "Endoplasmic reticulum,Centriolar satellite" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum, Centriolar satellite" "CAB009516: AB_2303048, HPA072354: AB_2686513" "unprognostic (3.59e-2)" "unprognostic (1.06e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.22e-2)" "unprognostic (4.92e-2)" "unprognostic (6.16e-3)" "unprognostic (2.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (3.02e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (6.58e-5)" "unprognostic (2.07e-2)" "unprognostic (4.69e-2)" "unprognostic (2.42e-2)" "unprognostic (2.21e-2)" 28.4 24.9 16.1 50.1 16.2 13.7 20.7 15.8 20.3 21.6 16.2 30.3 36.0 20.5 2.5 31.6 17.8 12.7 25.4 14.7 16.2 21.8 19.3 52.7 50.0 24.0 16.1 12.1 14.5 7.0 11.6 12.1 21.2 21.9 12.5 1.7 25.9 7.0 16.3 51.2 42.6 11.5 18.6 73.0 33.4 11.5 19.4 25.5 17.0 7.4 21.3 23.9 24.4 17.4 22.9 13.7 0.1 16.1 8.8 11.4 126.2 8.1 34.3 59.3 86.5 2.0 27.3 41.8 25.0 12.6 48.9 45.8 4.5 20.6 5.3 81.0 6.1 26.5 4.1 10.8 42.3 0.1 17.5 15.0 17.9 17.1 10.4 8.6 15.4 8.4 1.9 55.0 10.6 10.5 17.7 27.4 0.8 3.1 11.1 47.6 5.2 32.8 25.0 10.5 0.2 1.2 6.7 38.0 33.4 1.7 30.9 37.4 9.7 21.5 8.1 53.1 11.4 59.9 82.6 12.6 16.6 16.6 16.4 176.8 99.5 270.1 155.8 101.6 133.8 137.3 125.2 153.7 95.0 107.5 120.9 124.6 295.6 132.9 94.6 94.8 213.8 221.2 16.1 16.2 15.8 20.3 14.7 16.2 24.0 16.1 21.2 18.6 19.4 17.4 72.1 25.6 24.0 9.1 62.1 74.7 47.1 54.5 27.3 4.8 21.5 15.9 7.3 24.3 33.1 5.5 0.0 5.6 108.0 78.8 5.9 81.6 0.5 31.3 39.3 63.6 16.8 12.6 1.1 75.3 95.0 26.9 42.8 77.9 26.6 13.8 27.1 11.1 45.9 15.2 1.9 55.9 57.0 31.9 90.6 0.3 13.1 43.9 23.2 16.9 115.9 25.1 149.3 12.1 3.6 91.3 38.8 10.5 84.8 70.2 84.6 6.9 29.4 2.8 6.6 18.1 27.8 1.0 1.3 20.4 76.4 4.8 92.3 18.2 54.5 52.1 TAPBP TAPA ENSG00000231925 "TAP binding protein" O15533 6 33299694-33314387 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 168.7;Karpas-707: 140.8;U-266/70: 140.5" "Low region specificity" "Detected in all" HPA007066 Approved NA NA 20000 "Cluster 49: Eosinophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 1: Pancreatic cells - Digestion" "HPA007066: AB_1857769" "prognostic favorable (2.76e-4)" "unprognostic (1.43e-2)" "unprognostic (7.01e-2)" "unprognostic (1.98e-2)" "unprognostic (1.59e-3)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (8.21e-2)" "prognostic favorable (6.29e-4)" "unprognostic (1.67e-2)" "unprognostic (2.37e-1)" "unprognostic (3.63e-1)" "unprognostic (1.61e-2)" "unprognostic (3.82e-1)" "unprognostic (1.19e-2)" "unprognostic (1.21e-1)" "unprognostic (6.54e-3)" 47.3 73.1 2.4 28.5 4.8 25.0 43.1 1.9 2.8 40.1 1.2 66.7 52.3 38.2 13.3 57.3 43.8 10.5 63.7 2.9 1.8 67.4 107.5 82.1 21.2 2.7 3.2 33.3 48.2 14.9 38.8 18.7 2.0 64.3 19.6 4.1 61.9 17.2 26.7 54.0 81.9 23.1 1.9 129.0 52.1 16.2 2.0 24.4 59.1 6.5 36.7 45.0 43.4 2.4 3.3 1.2 6.3 26.1 20.3 25.6 92.9 18.5 88.1 42.5 57.1 0.1 168.7 48.1 38.1 41.3 92.2 2.9 0.3 30.3 15.8 125.5 4.1 19.1 9.9 24.8 0.2 20.4 63.0 51.7 20.6 0.8 8.2 37.8 0.4 16.0 1.5 140.8 14.7 19.6 51.9 44.1 0.5 0.0 6.3 2.8 0.4 1.3 35.5 1.2 8.6 0.6 0.6 2.4 23.7 3.7 1.4 0.9 45.5 89.4 18.6 1.3 2.0 140.5 117.4 46.2 58.6 38.8 58.8 159.7 87.9 172.1 137.3 121.6 117.0 97.1 99.7 114.3 90.0 86.0 76.2 109.9 151.3 159.6 139.0 102.9 85.9 150.5 2.4 4.8 1.9 2.8 2.9 1.8 2.7 3.2 2.0 1.9 2.0 2.4 116.8 125.0 102.1 22.5 186.6 77.0 93.3 148.2 66.6 34.7 82.0 64.1 73.9 84.4 105.8 71.7 33.3 46.9 223.7 259.6 13.7 256.4 1.9 64.0 52.4 99.1 84.6 58.0 25.9 282.9 85.9 63.9 105.5 78.4 91.9 65.9 75.0 143.7 119.7 20.2 15.0 174.6 83.4 124.3 128.0 9.2 33.2 131.9 119.2 30.9 229.3 34.7 195.7 23.6 8.7 215.5 172.4 32.0 194.9 130.4 283.2 33.1 113.3 30.4 32.9 39.3 57.6 1.2 0.6 53.6 56.3 49.1 163.7 66.4 162.3 141.0 TAPBPL "FLJ10143, TAPBP-R, TAPBPR" ENSG00000139192 "TAP binding protein like" Q9BX59 12 6451690-6466517 "Predicted intracellular proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Plasma cells: 94.2;Proximal enterocytes: 82.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 64.2;HDLM-2: 37.6;Karpas-707: 44.9;RPMI-8226: 36.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039545 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "HPA039545: AB_10673360" "prognostic favorable (1.98e-4)" "unprognostic (3.56e-1)" "unprognostic (4.58e-2)" "unprognostic (2.30e-1)" "unprognostic (1.32e-1)" "unprognostic (4.61e-2)" "unprognostic (1.91e-1)" "unprognostic (7.64e-2)" "unprognostic (4.07e-2)" "unprognostic (3.18e-1)" "unprognostic (5.66e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.04e-5)" "unprognostic (3.53e-2)" "unprognostic (7.61e-2)" "unprognostic (6.28e-2)" "prognostic favorable (7.86e-4)" 11.4 11.7 3.8 12.1 4.9 12.5 12.0 4.3 5.2 12.0 7.2 21.3 32.8 11.7 5.9 9.9 17.4 21.5 15.8 3.6 4.1 14.6 19.6 17.4 17.3 5.8 4.4 10.4 9.3 13.3 10.8 8.2 4.5 11.8 11.2 0.8 34.3 20.0 9.3 8.6 28.1 7.3 4.6 16.8 23.8 2.1 4.0 16.1 22.1 3.7 7.1 13.9 10.1 4.9 6.5 4.7 0.1 2.8 9.5 13.7 13.2 4.3 11.5 5.4 7.9 5.4 64.2 5.6 2.4 5.6 3.1 7.6 0.0 1.1 1.0 37.6 0.0 5.8 3.6 6.0 12.0 5.3 15.0 19.9 3.7 9.9 1.5 3.5 7.6 3.7 0.0 44.9 1.4 13.9 10.5 2.7 0.8 0.4 1.1 10.9 3.4 36.4 4.3 18.0 0.6 0.1 15.8 9.3 1.2 0.1 0.4 11.5 7.2 5.8 2.3 1.6 7.7 7.4 2.0 3.2 10.8 5.3 6.5 126.0 102.3 72.9 89.9 124.9 56.7 40.7 45.7 57.5 76.7 38.5 28.9 52.5 74.6 104.5 102.6 60.6 33.7 124.6 3.8 4.9 4.3 5.2 3.6 4.1 5.8 4.4 4.5 4.6 4.0 4.9 21.4 19.2 13.1 7.8 26.7 8.3 18.6 47.1 14.2 4.0 14.2 11.3 6.1 27.1 35.1 35.0 10.4 19.2 28.4 49.8 0.0 27.7 0.3 7.0 7.7 15.1 9.0 8.2 1.1 53.8 18.7 24.3 18.3 10.9 13.3 5.1 14.3 11.9 31.8 0.0 1.4 32.6 26.4 16.9 17.7 0.4 15.5 22.5 16.0 2.8 21.3 7.6 34.0 4.0 3.1 34.3 63.2 8.6 94.2 16.1 82.3 12.6 16.0 1.9 6.6 8.8 9.6 0.5 0.2 8.8 8.0 13.8 26.3 3.4 33.7 22.5 TAZ "BTHS, CMD3A, EFE, EFE2, G4.5, TAZ1, XAP-2" ENSG00000102125 Tafazzin Q16635 X 154411524-154421726 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039557 Approved Approved "Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA039557: AB_10672899" "unprognostic (1.14e-1)" "prognostic favorable (5.70e-4)" "unprognostic (4.94e-3)" "unprognostic (1.43e-1)" "unprognostic (8.29e-2)" "unprognostic (7.84e-2)" "unprognostic (1.56e-2)" "unprognostic (8.21e-3)" "unprognostic (1.69e-1)" "unprognostic (1.62e-1)" "unprognostic (4.68e-2)" "unprognostic (8.39e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (4.00e-3)" "unprognostic (4.20e-1)" "unprognostic (1.41e-1)" "unprognostic (3.79e-2)" 19.0 13.8 37.2 8.5 38.1 41.4 17.2 38.1 44.4 18.1 37.0 18.3 9.7 15.1 7.6 21.7 16.6 8.7 43.5 37.0 37.0 22.3 21.9 21.4 17.9 39.3 37.6 18.5 21.3 12.1 14.5 6.6 38.5 17.9 11.7 8.4 13.6 10.2 47.0 18.7 22.9 12.3 37.7 39.2 17.4 4.5 37.9 14.1 18.5 65.6 16.0 18.4 18.4 39.4 24.5 28.6 9.3 11.7 18.3 13.4 18.4 6.9 21.0 15.3 17.1 8.5 29.6 28.2 43.6 16.4 36.6 28.4 17.2 16.6 12.3 25.5 19.6 5.5 20.0 16.4 25.8 12.3 11.8 15.4 35.6 11.7 31.7 12.9 25.6 30.9 12.1 34.9 18.1 17.6 29.0 33.2 2.4 24.9 27.9 21.4 16.2 40.1 24.2 9.0 11.8 17.9 5.3 17.9 26.6 11.1 10.5 16.0 15.5 10.4 11.9 25.5 15.2 55.9 30.6 66.2 13.7 36.6 13.3 5.8 11.1 17.5 12.4 10.4 11.5 12.5 16.6 15.5 14.5 18.7 14.1 12.0 9.9 12.7 7.8 7.9 15.4 9.4 37.2 38.1 38.1 44.4 37.0 37.0 39.3 37.6 38.5 37.7 37.9 39.4 36.2 6.4 11.8 37.2 29.3 10.8 7.9 10.5 14.8 21.6 11.1 15.6 21.1 14.3 13.0 9.2 18.8 5.0 29.7 13.6 5.9 14.7 1.1 6.5 9.6 18.5 6.1 9.7 22.4 16.5 10.1 12.4 23.4 9.6 18.4 19.2 15.0 7.9 24.4 10.1 28.4 15.9 12.2 19.9 16.5 2.0 11.5 20.4 14.2 14.0 21.7 14.2 15.5 23.1 39.7 13.4 12.2 9.1 17.2 8.3 19.6 5.9 8.0 25.6 13.1 12.4 11.3 10.4 3.8 16.8 11.2 2.9 25.6 9.2 15.8 6.7 TBC1D16 "FLJ20748, MGC25062" ENSG00000167291 "TBC1 domain family member 16" Q8TBP0 17 79932343-80035872 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Horizontal cells: 307.9" "Cancer enhanced" "Detected in all" "melanoma: 35.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.3" "Lineage enhanced" "Detected in single" "monocytes: 2.3" "Cell line enhanced" "Detected in many" "ASC diff: 179.1;SK-MEL-30: 192.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024482, HPA065839" Approved Approved "Intermediate filaments" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Intermediate filaments" "HPA024482: AB_1857790, HPA065839: AB_2685566" "unprognostic (4.53e-3)" "unprognostic (1.36e-2)" "unprognostic (1.80e-2)" "unprognostic (2.06e-2)" "unprognostic (4.92e-2)" "unprognostic (7.21e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (5.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (9.76e-2)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-3)" "unprognostic (3.99e-3)" 37.3 8.1 17.6 8.7 24.8 0.9 18.4 24.4 14.6 10.4 5.3 8.0 7.9 12.4 11.5 10.1 12.9 9.5 10.7 10.6 15.2 27.7 7.4 9.0 7.8 18.0 22.7 11.7 15.7 12.9 7.0 7.5 16.0 17.7 5.9 7.6 29.4 10.8 5.1 17.3 9.0 10.5 13.0 7.3 8.4 4.1 38.9 4.0 10.1 6.7 3.5 8.6 6.2 17.4 30.3 28.2 43.1 50.8 179.1 93.7 8.2 17.3 17.1 10.7 12.0 53.6 10.3 0.1 11.9 29.2 20.3 9.4 45.8 16.2 8.2 1.5 21.5 0.0 13.3 25.1 30.5 0.6 4.1 106.1 28.1 23.2 16.7 17.1 45.9 19.8 7.2 19.6 20.2 18.4 8.1 2.7 51.8 39.3 15.4 25.4 27.2 17.5 12.6 36.5 43.8 56.8 15.4 42.5 192.4 26.7 27.9 13.6 31.3 37.1 26.1 29.5 15.3 59.9 11.4 3.3 15.9 11.2 47.8 0.0 0.1 0.0 0.0 1.9 0.2 0.0 0.0 0.1 0.1 0.5 0.1 0.1 0.0 0.0 2.3 0.0 0.0 0.2 17.6 24.8 24.4 14.6 10.6 15.2 18.0 22.7 16.0 13.0 38.9 17.4 5.7 0.0 7.9 15.7 1.7 5.5 5.2 4.3 2.8 8.5 12.3 7.5 8.1 17.2 5.5 7.3 10.4 6.1 0.3 3.1 9.8 15.1 0.9 15.3 22.7 10.4 31.8 3.6 7.3 22.1 1.5 17.5 9.7 26.0 7.6 23.8 14.6 17.9 3.2 307.9 8.9 6.3 14.2 58.4 3.1 2.2 5.9 6.4 76.5 37.5 0.9 23.1 2.1 14.6 4.9 17.4 4.8 7.9 0.4 12.5 3.5 13.5 8.2 7.0 6.6 19.3 10.3 0.3 4.3 5.8 4.5 1.9 2.7 7.6 7.0 5.9 TBC1D7 "dJ257A7.3, FLJ32666" ENSG00000145979 "TBC1 domain family member 7" Q9P0N9 6 13266542-13328583 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "melanoma: 13.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 320.4;U-266/84: 174.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034748 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "HPA034748: AB_10671232" "unprognostic (9.53e-2)" "unprognostic (8.39e-2)" "unprognostic (3.18e-1)" "unprognostic (1.81e-2)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (3.95e-3)" "unprognostic (5.54e-2)" "unprognostic (9.30e-2)" "prognostic favorable (4.98e-5)" "unprognostic (4.36e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (2.03e-7)" "unprognostic (1.57e-1)" "unprognostic (3.46e-2)" "unprognostic (3.48e-1)" "unprognostic (2.78e-2)" 9.4 12.0 14.3 9.7 15.9 26.5 11.5 13.0 26.3 10.8 9.9 15.2 14.5 8.4 20.0 17.1 6.6 10.3 31.7 14.3 12.9 21.4 17.5 11.0 13.9 11.8 11.6 7.7 10.2 12.4 10.7 14.4 13.4 12.4 16.5 11.5 12.2 7.0 16.2 13.8 10.8 10.1 10.7 12.3 9.8 14.0 12.7 16.9 8.0 14.5 15.6 10.0 11.4 15.8 26.2 25.5 36.0 36.8 27.5 15.7 24.9 11.5 13.3 24.0 26.8 51.8 23.0 18.1 75.0 19.3 55.8 20.8 24.5 29.0 21.9 28.4 29.1 50.3 16.5 45.8 63.6 32.7 73.6 21.4 40.6 29.7 19.3 24.0 40.5 57.2 57.3 23.7 30.8 42.8 42.2 78.5 24.4 32.4 24.6 61.7 15.7 77.7 54.1 35.1 69.4 30.8 28.4 55.4 320.4 71.3 53.6 19.1 29.4 24.6 30.8 13.6 16.2 55.8 174.2 86.2 23.1 34.1 51.1 28.2 21.6 27.0 11.6 20.0 7.6 15.4 9.9 10.5 43.3 14.5 9.1 11.1 42.2 21.4 13.7 42.2 14.6 10.4 14.3 15.9 13.0 26.3 14.3 12.9 11.8 11.6 13.4 10.7 12.7 15.8 11.0 12.8 13.9 3.9 16.2 7.5 9.9 37.2 11.4 6.5 15.7 20.6 30.6 15.7 28.8 16.5 4.2 41.0 15.0 12.9 33.2 16.4 8.1 15.2 12.7 12.4 9.0 57.4 8.4 14.3 23.3 9.9 15.8 15.7 9.5 14.4 12.1 15.2 24.2 10.1 9.5 18.3 50.8 12.9 23.0 5.8 4.4 31.3 10.6 4.7 13.9 8.9 13.4 6.6 7.3 22.2 18.3 5.3 21.9 11.6 13.1 56.1 16.4 8.0 13.1 5.6 20.2 14.7 34.3 21.7 8.9 46.9 11.3 14.4 16.4 13.4 TBK1 NAK ENSG00000183735 "TANK binding kinase 1" Q9UHD2 12 64452090-64502114 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease variant, Glaucoma, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045797, HPA060211" Uncertain Enhanced Nucleoplasm,Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Vesicles "HPA045797: AB_2679457, HPA060211: AB_2684222" "unprognostic (4.73e-2)" "unprognostic (8.46e-2)" "unprognostic (6.07e-3)" "unprognostic (1.90e-1)" "unprognostic (1.94e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.48e-4)" "unprognostic (1.69e-1)" "unprognostic (2.54e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (4.35e-2)" "unprognostic (1.30e-1)" "unprognostic (1.26e-2)" "unprognostic (9.56e-3)" 11.6 15.3 6.0 10.1 6.1 16.9 11.4 5.6 6.9 10.6 5.3 10.5 15.1 11.0 6.7 11.3 9.5 10.1 9.4 5.8 5.6 11.8 17.4 12.9 14.6 6.5 6.9 9.6 7.5 11.6 9.8 13.7 6.1 10.6 8.5 6.3 10.2 9.0 18.4 8.6 11.4 10.8 5.3 13.4 10.2 23.5 6.7 6.8 8.5 14.9 12.9 16.0 10.2 7.1 23.3 24.2 11.1 10.6 24.7 26.1 29.0 22.9 37.6 22.5 21.1 14.9 12.4 31.5 21.4 26.8 34.4 19.0 19.4 20.0 26.4 29.5 17.1 33.0 15.3 19.1 30.2 35.2 36.4 18.5 19.1 23.1 23.6 42.3 32.4 11.0 27.9 38.7 31.6 27.0 0.9 17.0 29.9 22.9 13.8 14.9 15.3 31.8 25.1 36.9 9.8 14.7 33.3 36.0 23.5 23.5 33.1 24.9 25.9 20.2 18.1 14.9 24.0 25.4 54.3 30.3 28.1 18.6 26.1 41.8 10.1 24.3 13.9 17.7 16.3 12.8 10.1 15.2 12.2 10.1 2.8 8.7 17.8 26.6 15.5 2.1 13.6 10.0 6.0 6.1 5.6 6.9 5.8 5.6 6.5 6.9 6.1 5.3 6.7 7.1 23.7 19.2 20.5 28.4 21.6 11.0 25.7 20.1 15.4 17.0 14.9 9.1 10.9 8.6 23.4 22.0 10.4 28.8 30.0 14.1 11.7 19.3 34.5 19.2 17.9 28.6 17.3 18.3 50.5 23.6 32.6 21.3 15.3 30.2 43.1 17.5 16.8 17.1 20.2 18.5 42.2 10.5 12.2 23.0 30.2 29.2 19.3 31.1 14.2 46.9 31.4 12.7 33.0 39.2 52.3 16.9 10.9 20.7 25.6 43.7 13.6 12.3 20.8 16.3 26.3 22.4 18.7 68.9 12.7 14.0 14.9 92.6 27.1 11.5 10.1 41.6 TBL1XR1 "C21, DC42, FLJ12894, IRA1, TBLR1" ENSG00000177565 "TBL1X receptor 1" Q9BZK7 3 177019340-177228000 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 280.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019182 Supported Approved Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA019182: AB_1857800" "unprognostic (4.11e-2)" "unprognostic (3.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.27e-3)" "prognostic favorable (5.16e-5)" "unprognostic (4.44e-2)" "prognostic unfavorable (1.08e-7)" "unprognostic (3.75e-1)" "unprognostic (4.84e-2)" "unprognostic (3.04e-1)" "unprognostic (3.13e-3)" "unprognostic (2.50e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (5.83e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" 18.8 20.3 7.2 24.4 12.7 30.2 21.7 13.9 11.8 24.9 8.5 31.0 24.6 16.9 9.2 21.2 22.4 23.2 32.6 16.0 3.3 22.3 24.5 19.6 31.3 8.1 8.5 20.9 12.1 27.3 2.9 21.0 4.9 25.6 24.4 42.7 16.1 14.8 12.9 17.1 18.7 19.4 8.6 22.9 22.3 19.1 8.4 45.5 47.1 25.3 36.3 25.3 10.3 15.0 96.8 41.2 61.1 39.7 56.2 65.8 44.2 26.1 52.3 30.3 36.3 48.9 76.2 98.9 132.9 43.6 58.4 61.2 42.9 63.2 58.7 97.5 14.5 56.2 66.8 30.3 49.7 91.0 29.6 95.3 35.9 37.3 90.6 53.8 48.5 68.5 44.8 189.9 42.8 31.0 81.7 14.0 38.1 59.8 32.2 53.9 72.6 124.6 33.1 119.5 24.8 38.7 43.3 35.9 49.8 37.3 113.0 74.3 60.5 48.9 35.3 28.8 65.6 89.8 117.6 280.7 32.9 66.2 56.1 14.3 3.7 3.8 5.6 6.2 5.9 7.5 6.9 7.3 4.6 7.3 5.9 7.4 12.9 7.4 5.5 12.4 8.3 5.3 7.2 12.7 13.9 11.8 16.0 3.3 8.1 8.5 4.9 8.6 8.4 15.0 55.1 73.7 60.7 128.0 56.5 91.5 55.1 90.6 62.0 113.6 69.2 42.2 101.9 47.1 80.3 104.8 125.1 28.9 70.0 84.7 29.4 52.2 7.4 90.9 59.0 65.5 85.3 60.4 228.9 43.8 35.1 81.8 44.4 134.5 25.3 65.9 48.5 66.6 37.8 116.1 167.6 72.6 59.0 91.1 75.0 9.0 64.0 69.4 65.8 184.6 55.8 47.6 41.2 241.8 269.4 66.7 43.7 73.0 75.1 144.9 41.5 67.3 83.9 81.6 46.0 76.3 54.4 12.9 61.4 88.1 111.8 27.5 66.0 41.6 84.6 83.6 TBL2 "DKFZP43N024, WBSCR13, WS-betaTRP" ENSG00000106638 "Transducin beta like 2" Q9Y4P3 7 73567537-73578791 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 44.2" "Group enriched" "Detected in all" 7 "Early spermatids: 398.2;Late spermatids: 515.4;Spermatocytes: 345.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007477, HPA051533" Supported Cytosol "Secreted in male reproductive system" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA007477: AB_1080214, HPA051533: AB_2681523" "unprognostic (9.04e-2)" "unprognostic (6.61e-3)" "unprognostic (4.24e-2)" "unprognostic (1.10e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.24e-3)" "unprognostic (7.50e-2)" "unprognostic (2.87e-1)" "unprognostic (1.90e-1)" "unprognostic (1.74e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.88e-5)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (1.42e-2)" "unprognostic (1.31e-1)" 4.9 9.1 1.7 5.3 1.8 1.6 4.2 2.8 5.4 4.6 2.7 4.7 5.4 4.5 8.3 5.4 4.3 2.7 4.0 1.9 1.7 4.2 5.9 5.5 1.9 1.7 1.6 4.8 16.4 5.6 3.2 4.4 1.8 4.4 5.5 4.0 11.0 4.3 2.9 4.9 4.3 4.6 1.6 3.1 6.4 44.2 1.7 2.3 4.9 1.5 3.2 3.6 4.5 1.8 22.1 27.5 8.7 12.6 19.9 18.2 10.2 26.9 18.4 9.3 17.1 40.9 22.0 18.4 5.4 21.7 19.5 15.9 18.2 9.5 19.4 6.8 10.8 6.6 11.8 26.3 28.5 13.3 22.4 11.4 15.0 28.7 22.1 16.7 10.2 2.4 26.0 12.6 14.7 20.2 13.2 10.7 8.7 23.8 18.1 8.6 14.6 38.8 10.5 16.0 8.4 14.3 25.8 65.8 16.9 10.1 17.2 5.7 18.7 17.1 8.8 17.1 25.7 25.8 18.0 20.0 23.3 15.3 21.3 16.8 11.1 4.9 6.3 7.3 5.9 3.0 5.0 5.2 13.6 4.1 5.9 3.7 1.4 8.8 7.4 10.2 6.5 8.1 1.7 1.8 2.8 5.4 1.9 1.7 1.7 1.6 1.8 1.6 1.7 1.8 8.6 25.6 9.3 3.3 8.1 4.6 14.5 17.3 4.0 10.8 10.8 6.3 4.7 11.5 13.5 5.5 8.4 45.2 6.5 12.7 1.9 26.1 398.2 11.3 14.9 12.6 9.5 6.3 4.1 30.1 54.6 17.3 7.7 11.6 14.0 13.9 10.0 14.7 27.4 3.3 4.5 16.8 6.1 9.4 3.8 515.4 23.6 17.5 7.2 4.7 17.3 8.1 10.3 4.5 4.1 22.6 13.7 26.7 19.9 17.1 14.6 5.1 9.8 13.4 6.6 13.8 15.1 345.8 27.9 7.8 3.7 43.4 5.0 17.0 15.8 9.0 TBX10 "TBX13, TBX7" ENSG00000167800 "T-box transcription factor 10" O75333 11 67631303-67639560 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 14 "intestine: 9.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 14.8;Intestinal goblet cells: 103.8;Paneth cells: 20.4;Proximal enterocytes: 42.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.4;NTERA-2: 5.3;RPMI-8226: 3.6;SK-BR-3: 12.5;U-2 OS: 2.5" "Low region specificity" "Detected in single" "HPA047881, HPA076197" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Cytosol "HPA047881: AB_2680199, HPA076197: " "unprognostic (4.66e-2)" "unprognostic (2.96e-2)" "unprognostic (7.71e-3)" "unprognostic (1.79e-1)" "unprognostic (2.37e-1)" "unprognostic (1.83e-4)" "unprognostic (3.12e-1)" "unprognostic (3.29e-2)" "unprognostic (5.10e-2)" "unprognostic (1.83e-1)" "unprognostic (4.90e-1)" "unprognostic (1.17e-10)" "unprognostic (6.77e-2)" "unprognostic (1.68e-1)" "unprognostic (2.95e-1)" "unprognostic (2.75e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 8.4 5.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 8.0 0.0 0.4 0.0 0.0 0.0 9.7 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 12.5 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.9 0.0 0.0 0.0 103.8 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 20.4 0.0 0.0 0.2 42.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.9 0.1 TCERG1L FLJ38950 ENSG00000176769 "Transcription elongation regulator 1 like" Q5VWI1 10 131092391-131311721 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.0;retina: 6.1;thyroid gland: 14.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 69.9;Horizontal cells: 102.6" "Cancer enriched" "Detected in some" 14 "thyroid cancer: 20.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.3;RPMI-8226: 1.1;SuSa: 1.9;U-2 OS: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA030816 Approved Nucleoplasm,Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "HPA030816: AB_10601721" "unprognostic (6.61e-2)" "unprognostic (1.29e-1)" "unprognostic (8.99e-2)" "unprognostic (1.45e-2)" "unprognostic (3.03e-1)" "unprognostic (6.69e-2)" "unprognostic (1.62e-1)" "unprognostic (4.96e-1)" "unprognostic (9.71e-2)" "unprognostic (2.02e-1)" "unprognostic (5.01e-2)" "unprognostic (1.08e-5)" "unprognostic (1.28e-1)" "unprognostic (2.83e-1)" "unprognostic (2.96e-2)" "unprognostic (2.03e-1)" 0.0 0.9 1.3 0.0 3.5 0.0 0.1 0.3 5.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 2.5 1.6 0.2 0.0 0.0 0.0 2.2 1.5 3.0 0.3 0.5 1.3 0.0 0.9 0.6 0.0 6.1 0.0 0.6 0.0 0.5 0.0 0.0 1.5 0.2 0.0 1.6 2.0 0.6 14.9 0.0 0.1 0.1 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.5 0.3 5.0 2.5 1.6 2.2 1.5 0.9 1.5 2.0 2.1 0.0 0.0 0.0 0.7 0.0 0.6 0.2 0.0 2.2 5.9 0.5 0.1 1.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 69.9 0.0 0.7 0.9 0.5 0.1 0.0 0.1 0.0 0.0 0.0 102.6 14.5 0.0 0.0 0.0 0.0 0.1 4.7 0.2 10.6 1.0 0.0 0.9 0.0 3.0 2.3 0.1 0.0 4.5 0.0 0.7 0.0 0.0 0.0 4.3 0.0 0.3 0.2 0.4 3.7 2.8 0.6 0.1 0.1 2.5 0.0 0.1 TCF4 "bHLHb19, E2-2, ITF2, SEF2-1B" ENSG00000196628 "Transcription factor 4" P15884 18 55222185-55664787 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1" "Cell type enhanced" "Detected in many" "Adipocytes: 820.0;Endothelial cells: 574.5;Inhibitory neurons: 1177.6;Oligodendrocyte precursor cells: 719.8;Oligodendrocytes: 573.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 65.1" "Group enriched" "Detected in many" 14 "memory B-cell: 173.6;naive B-cell: 146.8;plasmacytoid DC: 559.8" "Group enriched" "Detected in many" 33 "B-cells: 173.6;dendritic cells: 559.8" "Cell line enhanced" "Detected in many" "HDLM-2: 140.4;SH-SY5Y: 157.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020722, HPA025958" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "CAB020722: , HPA025958: AB_1857849" "unprognostic (2.11e-1)" "unprognostic (9.10e-2)" "unprognostic (8.69e-2)" "unprognostic (7.89e-3)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (3.03e-2)" "unprognostic (8.64e-2)" "unprognostic (1.79e-2)" "unprognostic (3.29e-2)" "unprognostic (2.77e-1)" "unprognostic (8.44e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (1.99e-3)" "unprognostic (2.68e-2)" "unprognostic (2.76e-3)" "prognostic unfavorable (9.95e-4)" 20.3 9.6 3.7 12.8 12.5 9.5 11.6 65.1 26.5 28.5 0.0 7.4 5.1 23.0 2.1 9.7 13.4 17.4 17.5 29.8 0.0 4.4 4.4 15.5 14.7 5.5 1.0 25.9 5.8 8.0 6.5 28.9 3.9 6.6 7.9 14.0 6.8 10.2 6.1 6.4 5.0 24.1 2.2 13.1 6.0 15.4 2.4 9.8 13.3 16.7 14.7 13.1 7.3 14.4 0.1 4.1 36.8 11.4 8.5 14.4 0.1 18.4 40.6 13.2 17.2 23.1 3.6 28.8 0.1 41.9 2.7 4.5 17.9 17.1 9.2 140.4 13.9 12.1 0.1 0.0 4.0 5.3 2.8 19.6 5.3 18.5 0.7 9.1 45.8 1.6 19.5 22.0 11.0 0.0 7.6 0.0 10.4 0.1 2.4 41.6 14.9 65.4 0.0 0.9 12.6 157.7 0.0 1.5 0.0 11.1 1.6 1.3 49.1 48.5 17.4 2.1 14.6 16.3 32.2 25.7 11.0 5.2 15.5 0.9 7.4 0.8 0.9 8.3 0.7 173.6 0.2 0.5 20.6 146.8 0.5 0.3 1.8 11.2 7.4 559.8 0.7 11.3 3.7 12.5 65.1 26.5 29.8 0.0 5.5 1.0 3.9 2.2 2.4 14.4 820.0 6.4 13.1 501.1 217.4 117.0 37.8 34.0 80.8 293.0 6.5 23.4 35.5 4.3 32.6 22.0 83.4 1.8 446.8 0.1 0.0 1.5 103.2 17.5 201.4 574.5 5.4 34.2 503.8 7.1 1.5 296.7 1.5 12.2 13.9 105.7 316.3 6.6 39.6 25.2 1177.6 0.3 26.4 112.4 129.2 116.3 205.3 80.4 64.0 474.1 32.7 372.8 13.4 719.8 573.6 2.1 0.1 182.1 131.7 20.8 0.0 2.3 25.9 54.7 236.7 304.5 221.0 8.7 14.5 47.5 84.4 2.6 15.1 164.8 0.2 17.8 TCF7L2 "TCF-4, TCF4" ENSG00000148737 "Transcription factor 7 like 2" Q9NQB0 10 112950247-113167678 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "brain: 244.9" "Cell type enhanced" "Detected in many" "Astrocytes: 264.8;Distal enterocytes: 260.0;Extravillous trophoblasts: 231.4;Paneth cells: 211.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 244.9" "Group enriched" "Detected in many" 10 "intermediate monocyte: 28.9;non-classical monocyte: 86.6" "Lineage enriched" "Detected in many" 14 "monocytes: 86.6" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in all" 9 "midbrain: 67.2;thalamus: 86.6" "Group enriched" "Detected in all" 5 "midbrain: 146.8;pons: 97.8;thalamus: 164.3" "CAB013535, HPA038800" Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB013535: AB_2533167, HPA038800: " "unprognostic (1.79e-2)" "unprognostic (3.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (4.59e-3)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-2)" "unprognostic (5.09e-1)" "unprognostic (7.10e-2)" "unprognostic (6.10e-3)" "unprognostic (3.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (3.64e-1)" "unprognostic (7.36e-3)" 28.1 9.4 47.4 8.6 6.3 7.6 25.0 0.2 12.1 18.9 1.0 22.9 20.4 25.1 6.7 9.9 18.1 9.4 11.3 4.3 46.9 9.9 22.4 13.9 5.4 5.1 98.0 22.9 12.4 11.1 9.6 17.7 1.7 12.3 21.3 4.6 14.5 13.1 8.4 17.2 19.3 16.4 1.6 22.2 23.3 7.6 244.9 5.8 12.9 6.9 3.7 13.8 14.3 3.2 15.0 37.8 40.7 39.6 20.8 13.7 48.5 10.3 20.0 7.1 8.5 24.9 45.3 0.1 11.3 19.4 9.6 10.5 14.0 17.6 9.1 1.7 13.1 10.4 25.2 23.6 22.0 4.2 3.7 24.4 6.3 11.0 18.2 29.7 12.0 8.8 11.0 0.7 8.2 28.0 6.7 2.5 29.2 16.6 21.6 19.0 29.8 6.9 15.2 20.4 0.8 12.4 15.7 15.4 17.0 31.5 10.0 2.2 27.9 6.8 18.7 16.9 21.3 2.6 0.3 0.4 6.5 8.7 14.9 0.4 4.5 0.4 1.5 28.9 0.9 0.0 0.4 1.2 4.1 0.0 0.4 0.6 6.0 0.0 86.6 0.2 0.0 3.5 47.4 6.3 0.2 12.1 4.3 46.9 5.1 98.0 1.7 1.6 244.9 3.2 62.0 22.4 26.5 264.8 3.3 42.6 27.3 35.8 64.9 2.8 53.0 54.9 13.6 52.9 35.5 40.5 6.2 44.2 9.1 260.0 11.7 39.3 8.8 40.1 140.6 46.1 19.8 4.8 35.1 43.6 231.4 90.8 90.2 64.2 0.0 37.6 52.8 74.2 17.5 5.0 16.6 87.7 16.2 99.9 20.6 5.0 59.0 54.6 32.0 107.7 22.4 34.4 5.2 192.5 34.9 59.0 211.1 48.5 6.0 38.4 75.3 16.2 26.8 6.1 92.1 37.3 51.3 9.4 28.9 61.1 39.8 28.5 6.7 13.1 73.9 49.0 TCIRG1 "a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7" ENSG00000110719 "T cell immune regulator 1, ATPase H+ transporting V0 subunit a3" Q13488 11 68039025-68050895 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 289.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 135.5;Kupffer cells: 115.2;Macrophages: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 131.9;RPMI-8226: 138.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038742 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria "HPA038742: AB_10795138" "unprognostic (5.35e-2)" "unprognostic (5.01e-2)" "unprognostic (1.81e-2)" "unprognostic (1.50e-2)" "unprognostic (6.98e-3)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (6.43e-2)" "unprognostic (7.03e-2)" "unprognostic (2.47e-2)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.50e-11)" "unprognostic (2.48e-3)" "unprognostic (7.88e-3)" "unprognostic (2.50e-1)" "prognostic favorable (9.45e-6)" 56.8 112.5 7.1 46.1 7.1 97.7 47.2 9.2 14.5 85.1 11.4 66.6 44.2 58.0 18.6 45.3 61.4 11.7 27.9 6.6 7.2 35.5 61.7 113.9 30.9 10.9 9.3 49.1 289.2 4.4 20.3 14.1 12.0 72.2 8.0 0.3 57.9 16.1 10.5 25.9 87.0 12.1 9.1 194.8 59.2 6.7 18.1 12.1 52.5 3.9 13.4 56.1 60.7 10.8 31.8 57.2 0.8 0.2 25.1 19.7 39.0 61.5 29.4 17.2 16.3 1.3 92.0 2.7 32.9 21.9 26.2 39.0 3.7 23.5 3.6 82.1 1.9 22.0 80.6 18.9 23.4 16.3 131.9 22.8 13.5 21.2 1.4 0.0 11.8 1.2 11.6 8.4 5.7 10.7 0.8 97.8 3.5 44.6 14.4 26.8 0.9 138.6 16.2 17.6 3.0 0.7 26.0 33.4 16.8 6.1 36.3 41.1 42.3 33.2 25.9 93.3 11.4 1.3 1.2 4.8 74.0 26.7 16.2 21.7 65.5 72.8 15.7 109.0 12.7 11.3 11.7 16.9 49.0 7.5 6.6 7.2 150.0 32.1 144.3 33.8 12.1 47.8 7.1 7.1 9.2 14.5 6.6 7.2 10.9 9.3 12.0 9.1 18.1 10.8 40.6 28.9 59.8 0.3 37.1 6.2 13.2 36.2 7.4 0.7 14.9 8.9 1.6 18.6 57.1 7.3 0.0 21.7 60.6 74.2 0.0 30.4 0.4 13.3 16.7 22.1 23.9 15.2 0.3 67.0 54.1 24.9 135.5 21.5 50.0 29.5 21.0 17.8 105.1 0.0 0.6 32.4 18.3 115.2 22.8 0.6 5.9 132.3 5.4 8.4 74.9 0.7 45.3 0.5 0.1 51.8 85.4 13.2 59.1 10.6 45.5 2.0 47.9 1.0 39.5 7.7 26.0 0.1 2.9 10.4 5.3 26.5 46.5 9.0 36.2 19.0 TCN1 "TC1, TCI" ENSG00000134827 "Transcobalamin 1" P20061 11 59852800-59866489 "Plasma proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "salivary gland: 776.3" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 52.0;Cholangiocytes: 62.9;Club cells: 94.9;Exocrine glandular cells: 372.3;Glandular and luminal cells: 84.7;Urothelial cells: 61.0" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 124.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 149 "basophil: 2374.2" "Lineage enriched" "Detected in many" 1592 "granulocytes: 2374.2" "Cell line enriched" "Detected in some" 21 "OE19: 159.0" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 4000000 "Cluster 18: Basophils - Vesicular transport" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" "prognostic favorable (1.90e-4)" "unprognostic (1.17e-1)" "unprognostic (5.89e-2)" "unprognostic (3.61e-3)" "unprognostic (2.49e-2)" "unprognostic (5.28e-3)" "unprognostic (4.52e-3)" "unprognostic (3.11e-3)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (9.07e-3)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.56e-8)" "unprognostic (2.50e-1)" "unprognostic (8.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" 0.1 0.2 0.0 0.7 0.0 190.7 5.4 0.0 0.2 31.7 0.0 0.2 9.6 3.1 0.0 23.0 1.4 173.8 0.1 0.0 0.0 0.1 0.4 1.4 0.3 0.0 0.0 0.0 5.3 108.5 0.2 0.5 0.0 1.2 0.8 0.0 776.3 0.0 0.1 0.9 1.0 0.0 0.0 4.5 76.3 0.3 0.0 1.3 0.0 0.0 0.9 15.5 10.7 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 2.2 0.0 0.8 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.6 0.0 159.0 7.5 0.0 0.2 0.0 1.5 0.0 0.0 0.0 7.3 0.0 1.6 0.0 0.0 3.0 0.1 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.2 2374.2 0.0 0.3 0.0 0.1 0.2 0.2 0.3 0.0 0.2 0.1 0.2 0.4 15.9 0.1 1.4 0.1 0.3 4.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 19.2 52.0 0.0 0.0 21.9 4.2 0.2 62.9 94.9 23.9 0.0 0.0 0.5 0.3 0.0 23.7 0.4 2.2 8.0 0.4 0.0 0.0 0.1 372.3 0.0 0.1 3.6 84.7 0.0 0.0 0.0 0.3 0.2 0.0 0.1 1.2 12.2 0.6 0.3 0.0 0.3 0.9 0.0 0.0 0.7 0.0 0.0 0.5 0.0 46.5 0.0 0.0 0.1 5.0 0.0 0.3 11.7 0.0 0.0 0.0 2.5 0.0 0.0 6.0 0.1 0.0 0.5 0.0 0.2 61.0 TCN2 "D22S676, D22S750, TC2" ENSG00000185339 "Transcobalamin 2" P20062 22 30607003-30627271 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Hepatic stellate cells: 137.4;Kupffer cells: 144.1;Proximal enterocytes: 563.6;Proximal tubular cells: 125.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 43.8;intermediate monocyte: 66.5;non-classical monocyte: 24.4" "Lineage enriched" "Detected in many" 8 "monocytes: 66.5" "Cell line enhanced" "Detected in many" "ASC TERT1: 117.6;HUVEC TERT2: 142.6;Karpas-707: 184.0;RPTEC TERT1: 70.7;TIME: 85.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000837 Approved Cytosol "Secreted to blood" NA NA 19000000 "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA000837: AB_1080235" "unprognostic (6.43e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.53e-3)" "unprognostic (3.17e-1)" "unprognostic (1.49e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.64e-4)" "unprognostic (1.52e-2)" "unprognostic (2.90e-1)" "unprognostic (1.07e-1)" "unprognostic (4.03e-2)" "unprognostic (1.59e-1)" "unprognostic (6.95e-3)" "unprognostic (4.94e-3)" "unprognostic (2.09e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" 49.6 30.6 24.6 16.0 24.1 5.5 37.9 25.5 30.6 25.9 27.1 23.4 23.6 28.7 20.3 8.6 21.5 50.1 28.7 22.7 25.3 115.8 17.3 37.7 35.3 27.1 26.1 14.8 12.1 8.6 15.1 18.6 27.7 16.0 27.8 11.1 13.2 45.4 6.0 9.0 59.5 36.8 25.5 46.7 17.4 21.9 29.7 6.4 26.4 13.7 10.0 22.0 14.7 25.3 0.2 9.5 41.8 0.2 24.6 117.6 1.4 3.1 30.9 8.0 13.1 4.6 21.2 0.6 45.7 6.2 0.7 1.5 3.7 2.2 2.5 0.0 2.3 0.2 1.2 2.0 58.5 0.6 33.7 19.8 2.5 6.1 5.1 8.8 142.6 0.0 0.8 184.0 12.7 0.1 0.1 3.3 16.4 11.7 1.0 4.9 6.0 64.2 70.7 1.1 14.4 1.9 0.3 0.6 12.0 2.8 0.4 2.0 85.3 26.4 3.5 3.3 1.3 5.1 1.4 0.2 9.5 1.7 0.6 0.0 43.8 0.0 0.1 66.5 0.7 0.0 0.8 0.4 7.9 0.0 0.3 0.6 1.4 0.0 24.4 1.5 0.2 18.8 24.6 24.1 25.5 30.6 22.7 25.3 27.1 26.1 27.7 25.5 29.7 25.3 105.0 3.2 3.9 3.9 3.7 5.2 2.2 4.7 0.6 8.0 7.1 5.1 6.5 27.1 13.7 12.9 20.9 0.4 0.5 70.9 7.9 7.8 1.1 3.5 5.4 64.6 6.7 0.8 0.2 6.0 0.8 19.5 5.1 6.2 4.5 23.4 137.4 5.6 45.9 1.7 1.9 28.6 4.1 144.1 9.4 1.4 10.5 53.8 23.2 8.4 8.8 7.4 0.0 5.5 1.7 5.1 50.2 9.8 13.5 2.0 563.6 125.8 2.8 29.1 13.1 0.9 5.5 1.0 12.6 0.5 5.3 0.4 2.2 5.6 21.0 2.7 TCTN1 "FLJ21127, JBTS13, TECT1" ENSG00000204852 "Tectonic family member 1" Q2MV58 12 110614027-110663431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 98.9;Respiratory ciliated cells: 203.7;Spermatocytes: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039687, HPA040036" Approved Approved "Nucleoplasm,Vesicles,Actin filaments,Microtubules" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "Nucleoplasm, Vesicles, Microtubules" "HPA039687: AB_10795293, HPA040036: AB_10794759" "unprognostic (2.54e-1)" "unprognostic (7.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (1.13e-5)" "unprognostic (2.89e-2)" "unprognostic (6.53e-2)" "unprognostic (2.11e-1)" "unprognostic (3.05e-2)" "unprognostic (6.02e-2)" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (9.60e-2)" "unprognostic (9.97e-2)" "unprognostic (2.15e-2)" "unprognostic (8.41e-2)" "unprognostic (1.24e-1)" "unprognostic (4.27e-2)" 8.8 14.0 5.6 2.0 5.3 1.0 8.4 9.3 7.5 10.1 18.2 7.1 1.5 9.0 10.7 4.5 15.3 5.6 17.0 5.7 4.5 19.0 9.1 8.3 2.5 4.5 5.0 12.8 10.8 15.2 26.2 4.0 4.4 10.0 0.9 3.0 9.5 6.1 10.3 5.3 4.0 3.6 3.6 4.6 6.9 21.1 5.2 1.3 17.6 1.9 0.8 7.7 7.0 7.0 11.6 11.7 6.7 17.6 24.9 18.0 4.3 6.3 16.2 5.9 4.4 1.2 2.7 2.0 6.9 18.6 7.2 6.1 4.7 4.6 5.0 4.7 8.7 0.3 4.1 3.6 8.6 1.2 1.3 14.8 7.8 7.7 7.9 34.7 3.3 3.0 7.4 2.5 9.7 9.4 0.9 2.2 4.1 3.5 16.7 2.4 2.9 14.6 16.8 1.8 5.5 11.7 13.1 1.6 5.3 5.5 22.7 16.0 4.0 8.2 2.4 3.5 6.0 4.2 2.6 2.6 11.1 1.3 9.3 0.0 2.0 0.0 0.8 3.6 2.2 4.9 1.5 2.5 3.4 9.1 2.2 1.6 6.4 1.0 1.9 4.3 0.5 2.0 5.6 5.3 9.3 7.5 5.7 4.5 4.5 5.0 4.4 3.6 5.2 7.0 6.5 3.2 18.8 25.5 24.0 13.8 28.4 38.4 18.2 10.7 22.8 19.3 13.0 24.3 26.0 16.5 31.3 30.9 5.8 1.0 9.8 24.3 82.7 98.9 29.0 11.5 18.0 1.3 15.0 4.7 8.5 30.5 8.2 9.8 3.8 27.1 9.3 6.9 11.8 3.3 12.1 4.8 32.6 3.8 12.4 18.7 17.1 7.0 23.2 7.5 1.7 30.5 0.0 12.5 9.3 4.2 2.4 28.6 9.6 20.0 0.4 42.5 203.7 34.1 6.6 16.2 18.3 96.9 30.1 8.5 11.2 18.3 4.2 38.1 4.7 16.6 TCTN2 "C12orf38, FLJ12975, JBTS24, MKS8, TECT2" ENSG00000168778 "Tectonic family member 2" Q96GX1 12 123671110-123708399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.6;Respiratory ciliated cells: 32.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039900 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus, Vesicles" "HPA039900: AB_10673366" "unprognostic (3.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-2)" "unprognostic (1.63e-3)" "unprognostic (1.32e-1)" "unprognostic (3.09e-3)" "unprognostic (3.14e-2)" "unprognostic (7.05e-2)" "unprognostic (1.09e-1)" "unprognostic (3.97e-3)" "unprognostic (2.23e-1)" "unprognostic (1.69e-1)" "unprognostic (2.79e-1)" "unprognostic (2.46e-1)" "unprognostic (7.86e-2)" "unprognostic (2.68e-1)" 5.3 4.4 5.5 2.6 6.4 1.9 7.2 5.8 5.3 10.0 30.4 5.7 2.1 11.0 11.0 3.4 28.5 6.4 4.8 4.9 9.5 10.0 1.4 8.3 3.3 8.4 11.5 14.7 6.9 14.1 16.3 4.6 6.5 9.6 4.0 17.6 9.1 8.6 1.7 8.3 3.8 6.0 7.1 4.1 5.4 11.1 8.7 2.5 12.4 2.1 3.0 5.2 6.7 4.1 14.9 15.1 10.7 15.6 15.0 16.5 13.1 5.4 10.9 11.5 8.7 7.9 14.5 0.5 9.2 8.9 10.0 19.6 6.2 4.9 11.2 2.5 7.6 1.2 10.6 7.2 5.0 3.7 4.8 8.0 8.8 16.3 4.8 34.9 15.7 5.1 7.1 0.3 7.1 7.9 4.5 7.4 6.8 5.9 9.1 4.0 10.8 1.5 13.7 11.1 6.5 8.3 18.2 6.0 8.4 11.0 25.5 5.6 9.8 16.0 8.2 14.7 7.1 4.3 8.9 1.4 20.9 0.4 9.7 1.7 0.2 1.2 1.9 0.6 2.7 1.9 2.2 2.0 0.4 2.1 2.4 2.4 0.3 0.8 0.5 2.5 1.4 0.2 5.5 6.4 5.8 5.3 4.9 9.5 8.4 11.5 6.5 7.1 8.7 4.1 2.7 3.2 5.3 6.5 1.8 4.1 2.3 2.6 1.2 4.4 4.8 2.3 3.8 5.7 3.9 7.3 12.5 2.8 2.1 1.2 0.0 2.9 6.1 27.6 5.0 1.7 1.2 2.5 10.4 2.1 3.0 4.6 2.6 4.3 3.8 5.0 2.9 0.4 1.3 0.0 14.4 1.8 2.0 0.3 1.2 2.8 2.5 1.0 5.4 2.8 1.4 4.6 1.0 2.5 1.3 2.0 0.8 4.9 1.1 1.4 0.2 1.9 32.1 14.5 0.0 6.0 2.7 11.5 10.9 0.6 2.3 1.1 2.4 2.3 3.0 1.0 TCTN3 "C10orf61, DKFZP564D116, JBTS18, TECT3" ENSG00000119977 "Tectonic family member 3" Q6NUS6 10 95659823-95694143 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026987 Approved Approved Microtubules "Intracellular and membrane" NA NA 4400000 "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Microtubules "HPA026987: AB_10600911" "unprognostic (1.58e-1)" "unprognostic (1.54e-1)" "unprognostic (9.78e-2)" "prognostic favorable (5.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.50e-2)" "unprognostic (8.88e-3)" "unprognostic (1.08e-1)" "unprognostic (3.03e-2)" "unprognostic (9.25e-3)" "unprognostic (3.78e-3)" "unprognostic (7.29e-2)" "unprognostic (4.60e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (9.30e-3)" "unprognostic (1.59e-1)" 21.3 25.3 8.6 15.7 9.0 5.1 25.2 9.1 11.3 26.3 24.0 22.1 17.6 24.8 65.0 17.0 35.4 22.7 18.4 8.8 9.8 32.5 26.8 19.4 14.3 9.7 9.5 30.6 27.1 69.9 22.8 26.9 9.5 25.6 25.6 22.2 25.4 27.7 9.5 20.5 15.4 26.8 9.2 17.3 19.1 19.4 9.6 14.0 70.6 11.5 18.0 23.9 18.6 9.2 34.0 54.1 44.1 89.3 93.6 74.6 25.7 45.3 94.8 46.9 55.3 35.4 57.3 31.3 40.1 60.4 49.8 46.7 43.9 54.5 56.5 33.6 36.4 10.9 21.6 49.2 46.9 37.4 22.8 65.2 49.2 46.6 72.4 88.0 80.7 27.7 21.0 40.3 63.4 32.5 23.4 27.9 12.1 49.7 38.1 25.3 33.9 38.3 67.8 23.3 11.5 24.5 37.7 18.5 52.6 40.8 71.0 35.1 37.9 35.6 24.9 23.9 49.5 18.9 37.9 20.7 57.5 47.1 19.0 6.8 14.2 4.9 25.8 21.9 32.0 28.3 23.1 25.2 45.2 19.4 24.2 20.0 1.6 26.8 24.3 23.6 22.2 21.3 8.6 9.0 9.1 11.3 8.8 9.8 9.7 9.5 9.5 9.2 9.6 9.2 14.8 19.2 16.2 16.6 29.3 14.4 23.7 33.8 31.3 24.0 18.2 15.0 8.5 27.1 20.3 31.3 37.5 50.3 18.8 20.2 7.9 27.2 18.6 25.5 25.7 20.4 13.8 11.6 17.3 20.3 44.2 27.3 11.7 18.3 8.2 29.8 21.4 16.8 28.5 25.2 17.7 12.5 26.4 14.1 59.1 14.1 20.8 18.7 16.0 16.9 14.8 36.7 15.5 20.6 13.7 14.1 12.7 25.2 35.9 19.8 16.2 16.1 27.5 44.4 13.1 23.9 19.8 39.8 34.1 15.3 11.5 31.5 23.0 34.2 23.7 14.6 TDGF1 "CR, CR-1, CRIPTO, Cripto-1" ENSG00000241186 "Teratocarcinoma-derived growth factor 1" P13385 3 46574534-46582457 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.4;lymphoid tissue: 20.9" "Cell type enriched" "Detected in some" 6 "Distal tubular cells: 121.3" "Cancer enriched" "Detected in many" 4 "testis cancer: 27.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 25.7;NTERA-2: 110.6;SuSa: 66.3" "Group enriched" "Detected in many" 5 "cerebellum: 11.2;pons and medulla: 8.7" "Low region specificity" "Detected in single" HPA051928 Uncertain Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Vesicles Cytosol "HPA051928: " "unprognostic (7.84e-3)" "unprognostic (2.00e-2)" "unprognostic (1.30e-2)" "unprognostic (1.17e-2)" "unprognostic (2.80e-2)" "unprognostic (1.14e-1)" "unprognostic (4.01e-2)" "unprognostic (1.93e-1)" "unprognostic (3.61e-1)" "unprognostic (1.72e-2)" "unprognostic (6.77e-2)" "unprognostic (1.74e-1)" "unprognostic (8.76e-3)" "unprognostic (2.01e-1)" "unprognostic (2.10e-2)" "unprognostic (1.75e-2)" "unprognostic (1.05e-1)" 0.4 3.4 2.4 0.5 1.9 0.3 0.3 2.1 4.8 0.7 1.4 2.6 0.7 1.0 2.0 0.1 0.1 0.6 0.6 1.8 1.7 23.4 1.3 0.4 0.4 2.1 1.8 7.7 0.4 0.1 0.1 0.2 2.2 0.4 4.6 0.4 1.0 0.3 1.5 0.3 0.5 1.2 1.7 20.9 2.7 0.5 3.1 15.1 0.8 1.5 0.1 0.2 0.1 1.9 0.1 0.2 0.1 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 1.8 0.0 0.2 0.0 0.0 25.7 0.2 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.2 110.6 4.0 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 66.3 0.1 0.1 1.8 0.2 0.1 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.7 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.9 0.3 0.1 0.1 0.0 0.0 2.4 1.9 2.1 4.8 1.8 1.7 2.1 1.8 2.2 1.7 3.1 1.9 0.9 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.5 0.0 0.0 0.0 0.9 121.3 0.2 5.0 0.3 0.1 8.2 2.4 0.0 0.0 0.0 0.0 0.3 8.2 0.2 0.0 14.3 0.4 1.4 0.1 0.0 0.0 5.5 0.0 0.0 0.0 1.0 0.3 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.3 0.6 0.0 0.2 0.0 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.1 17.7 6.1 0.0 TDP2 TTRAP ENSG00000111802 "Tyrosyl-DNA phosphodiesterase 2" O95551 6 24649979-24666930 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" "Hydrolase, Nuclease" "Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 183.2" "Cell type enhanced" "Detected in all" "Distal enterocytes: 530.9;Paneth cells: 428.1;Proximal enterocytes: 637.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 75.6;neutrophil: 228.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 228.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB073398, HPA074011" Enhanced Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nuclear bodies" "CAB073398: , HPA074011: AB_2686651" "unprognostic (2.46e-2)" "unprognostic (2.10e-3)" "unprognostic (1.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.58e-1)" "unprognostic (4.66e-3)" "unprognostic (4.13e-3)" "unprognostic (3.24e-1)" "unprognostic (5.78e-3)" "prognostic favorable (2.53e-7)" "unprognostic (1.20e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (1.40e-2)" "unprognostic (1.42e-1)" "unprognostic (9.70e-3)" "unprognostic (1.14e-1)" "prognostic favorable (1.47e-5)" 24.4 23.7 27.4 34.3 28.4 21.8 27.3 30.4 36.4 20.6 30.4 141.6 120.1 19.7 25.3 18.6 22.6 28.6 28.2 28.0 28.9 77.9 51.2 24.5 38.9 28.2 29.5 21.3 29.5 25.7 20.3 20.1 28.7 56.5 127.4 18.9 21.9 21.7 21.9 21.1 183.2 24.6 28.3 27.9 26.2 25.3 32.1 37.5 21.7 26.3 37.7 27.2 16.5 28.3 47.7 37.1 41.5 48.1 63.0 64.0 32.4 41.4 53.1 38.9 51.9 50.8 26.3 57.0 70.1 43.8 90.0 34.2 51.2 47.3 52.9 73.6 53.1 53.4 37.7 84.2 40.1 82.8 49.5 43.1 43.7 40.7 36.5 46.0 63.9 54.1 48.8 23.7 59.2 34.1 64.7 52.8 37.1 54.7 31.8 55.5 43.7 61.6 67.0 66.5 52.2 29.8 33.6 84.5 71.0 42.2 38.9 47.4 48.0 37.6 31.3 28.3 61.4 33.7 107.9 77.1 26.0 107.5 61.3 75.6 13.9 29.4 25.0 14.8 30.8 20.0 28.8 27.9 13.2 14.5 24.0 26.2 228.9 29.0 16.5 12.4 31.9 22.7 27.4 28.4 30.4 36.4 28.0 28.9 28.2 29.5 28.7 28.3 32.1 28.3 24.0 6.4 16.7 23.5 24.1 14.1 25.1 37.0 18.8 12.7 19.8 20.2 23.4 37.1 29.6 22.0 6.2 18.4 23.0 530.9 49.0 35.4 140.6 19.4 16.6 22.5 52.7 20.8 25.9 36.0 23.6 18.3 14.3 19.7 24.1 15.7 27.5 31.4 68.4 6.7 25.8 168.9 30.5 28.9 20.0 80.2 18.0 33.5 12.4 15.0 61.7 19.5 38.1 11.6 21.2 21.4 428.1 23.3 10.7 37.0 637.5 175.8 30.5 15.8 32.9 19.1 20.4 9.0 32.7 10.4 16.6 44.3 28.5 15.7 119.3 31.9 TEAD1 "AA, TCF13, TEF-1" ENSG00000187079 "TEA domain transcription factor 1" P28347 11 12674421-12944737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 230.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057339, HPA062471" Enhanced Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA057339: AB_2683413, HPA062471: AB_2684773" "unprognostic (1.00e-1)" "unprognostic (2.53e-2)" "unprognostic (8.84e-2)" "unprognostic (9.93e-3)" "unprognostic (2.05e-2)" "unprognostic (4.50e-1)" "unprognostic (1.50e-1)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" "unprognostic (4.40e-3)" "unprognostic (8.39e-2)" "unprognostic (4.76e-2)" "unprognostic (1.41e-2)" "unprognostic (7.08e-3)" "unprognostic (2.52e-1)" "unprognostic (3.14e-1)" "unprognostic (2.18e-2)" 29.5 12.1 11.1 8.2 11.6 0.0 17.8 8.6 8.5 23.4 30.6 36.1 7.7 26.4 7.1 29.8 19.2 18.5 31.3 14.5 14.8 17.2 13.6 15.9 4.2 15.1 12.3 21.9 15.2 27.1 14.4 33.3 10.5 18.8 13.0 10.5 10.2 20.1 67.5 13.2 11.9 27.2 13.3 7.3 16.4 8.6 15.6 4.2 17.8 72.6 5.6 33.9 14.7 12.9 62.8 52.1 43.9 58.7 59.9 62.1 65.4 89.2 76.2 71.6 69.7 53.8 54.5 0.4 23.0 120.9 32.3 37.0 53.7 35.9 115.5 0.2 17.6 0.0 107.3 18.1 55.8 0.0 4.7 51.8 18.3 50.4 68.2 58.6 15.2 3.9 26.0 0.2 111.2 13.1 0.1 0.6 17.2 14.5 23.5 0.3 64.8 33.2 48.2 37.2 26.9 31.2 90.9 43.1 59.0 63.8 20.0 4.4 32.0 107.8 76.2 84.9 59.5 8.6 17.3 12.0 41.6 0.2 69.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 11.6 8.6 8.5 14.5 14.8 15.1 12.3 10.5 13.3 15.6 12.9 37.9 89.8 21.7 230.8 0.4 99.3 32.2 19.3 39.9 12.9 16.4 20.2 75.0 31.5 33.1 49.7 12.5 24.1 0.2 11.0 1.9 16.6 6.5 80.8 97.4 33.3 46.7 0.0 101.8 12.8 52.4 46.5 18.8 142.9 0.0 57.7 25.7 39.8 3.7 1.7 108.4 13.5 10.2 1.9 16.0 7.2 23.6 1.9 24.9 91.8 0.0 31.2 0.0 121.2 69.7 34.8 8.1 24.0 1.4 69.4 6.7 29.8 53.8 17.5 6.6 73.5 46.7 3.0 22.3 29.9 54.8 12.3 2.0 45.5 10.4 54.6 TECTB ENSG00000119913 "Tectorin beta" Q96PL2 10 112283400-112305038 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Late spermatids: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted in other tissues" NA NA "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.14e-2)" "unprognostic (2.84e-2)" "unprognostic (9.75e-3)" "unprognostic (1.65e-1)" "unprognostic (1.32e-2)" "unprognostic (5.54e-2)" "unprognostic (2.80e-2)" "unprognostic (8.10e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TEDC1 C14orf80 ENSG00000185347 "Tubulin epsilon and delta complex 1" Q86SX3 14 105489855-105499575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 11.6;Endometrial ciliated cells: 12.0;Exocrine glandular cells: 12.7;Extravillous trophoblasts: 26.6;Hofbauer cells: 14.6;monocytes: 11.9;Pancreatic endocrine cells: 14.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 66.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA039049, HPA039050" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 6: Brain - Smell perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039049: AB_2676320, HPA039050: AB_10670918" "unprognostic (8.06e-2)" "unprognostic (1.06e-2)" "unprognostic (9.17e-2)" "unprognostic (1.65e-1)" "unprognostic (3.06e-1)" "unprognostic (1.57e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (5.19e-2)" "unprognostic (1.49e-1)" "unprognostic (3.12e-1)" "unprognostic (3.81e-2)" "unprognostic (2.91e-2)" "unprognostic (1.12e-3)" "unprognostic (8.73e-3)" "unprognostic (2.88e-1)" "unprognostic (1.17e-1)" "unprognostic (6.18e-3)" 5.1 1.6 5.2 4.9 5.5 6.8 4.7 4.1 7.8 4.3 0.5 5.5 5.1 3.8 1.0 6.8 4.6 1.8 4.3 5.8 3.0 4.0 5.4 4.9 5.4 7.0 3.5 2.5 3.0 1.0 5.3 1.6 4.2 4.2 1.6 0.5 4.3 2.3 2.3 8.2 5.4 1.0 3.1 6.8 5.9 4.9 3.6 4.5 5.7 0.5 3.1 3.9 4.5 5.3 17.2 38.9 9.2 13.5 0.8 1.5 24.5 13.4 5.0 15.9 14.7 14.0 31.2 25.6 27.2 2.2 6.2 43.5 3.2 14.0 3.0 29.0 16.0 6.5 22.8 13.3 0.6 12.9 17.9 0.3 4.6 10.6 3.5 2.0 6.4 23.2 10.5 31.2 2.5 66.7 26.9 29.6 11.9 14.6 41.8 21.9 13.8 17.9 4.5 14.3 25.7 15.5 13.7 15.8 9.8 2.0 26.0 12.6 7.8 10.9 18.4 33.4 22.4 17.8 8.2 15.7 13.9 14.8 18.0 0.0 0.5 0.6 0.5 0.9 0.4 0.1 0.8 1.4 0.7 0.3 0.6 0.1 0.1 0.0 0.8 2.4 0.6 0.2 5.2 5.5 4.1 7.8 5.8 3.0 7.0 3.5 4.2 3.1 3.6 5.3 4.8 3.2 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 5.9 5.3 0.0 0.0 0.6 1.8 0.0 8.0 10.1 0.0 3.9 11.6 0.0 12.0 3.0 4.0 0.0 0.0 0.0 12.7 26.6 3.4 0.0 7.2 0.0 8.1 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 11.9 0.0 0.0 0.0 0.0 14.7 0.0 0.0 4.7 0.0 0.0 2.0 3.6 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 4.0 4.2 2.5 0.0 0.0 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TENT5B "FAM46B, MGC16491" ENSG00000158246 "Terminal nucleotidyltransferase 5B" Q96A09 1 27005020-27012850 "Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 111.8;skin 1: 121.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 26.8;Breast myoepithelial cells: 24.8;Distal tubular cells: 23.5;Endometrial ciliated cells: 11.7;Glandular and luminal cells: 10.8" "Cancer enhanced" "Detected in many" "testis cancer: 87.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 62.0;hTERT-HME1: 31.6;NTERA-2: 32.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.67e-2)" "unprognostic (5.94e-3)" "unprognostic (1.61e-1)" "unprognostic (5.28e-3)" "unprognostic (3.20e-2)" "unprognostic (2.22e-2)" "unprognostic (2.44e-4)" "unprognostic (4.05e-2)" "unprognostic (1.39e-1)" "unprognostic (6.02e-3)" "unprognostic (1.34e-1)" "unprognostic (1.11e-1)" "unprognostic (1.00e-1)" "unprognostic (5.82e-2)" "unprognostic (4.85e-2)" "unprognostic (1.01e-1)" "unprognostic (1.46e-2)" 8.5 0.9 0.5 2.6 0.5 0.0 15.7 1.5 0.8 30.9 0.5 45.9 1.1 24.8 0.8 111.8 16.4 1.8 26.3 0.4 0.7 5.8 0.4 12.8 0.2 2.2 0.5 3.6 1.9 1.9 2.6 3.2 1.3 12.3 1.7 3.0 27.6 15.5 2.1 121.3 10.6 12.2 0.3 0.6 17.4 6.4 0.5 0.6 5.0 1.7 5.5 37.3 47.3 0.5 3.9 0.6 7.6 2.3 0.9 1.2 1.9 5.5 1.8 21.5 8.5 15.3 5.0 0.0 9.1 3.0 4.8 12.4 1.3 20.1 5.8 0.0 1.2 0.2 2.9 2.6 10.6 0.1 0.3 4.8 62.0 6.6 31.6 0.0 0.3 0.0 0.4 0.0 2.8 3.0 0.0 1.2 32.8 2.8 1.5 0.4 0.0 0.2 21.3 0.0 0.9 0.6 10.6 23.4 14.3 15.9 18.6 0.3 0.5 5.2 18.0 0.6 1.1 0.3 0.8 0.0 1.1 0.1 3.3 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 1.5 0.8 0.4 0.7 2.2 0.5 1.3 0.3 0.5 0.5 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 26.8 24.8 0.0 0.0 0.0 0.0 0.0 3.2 0.4 0.0 23.5 1.8 0.0 11.7 1.8 0.5 0.0 0.0 0.0 1.9 3.1 0.5 0.0 10.8 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 5.3 0.1 0.0 0.0 0.0 TEPSIN "C17orf56, ENTHD2, FLJ31528" ENSG00000167302 "TEPSIN adaptor related protein complex 4 accessory protein" Q96N21 17 81228277-81239091 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 9.9;Syncytiotrophoblasts: 10.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063410 Approved "Nuclear membrane,Nuclear speckles,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear membrane, Nuclear speckles, Golgi apparatus" "HPA063410: AB_2685008" "unprognostic (6.90e-3)" "unprognostic (1.03e-2)" "unprognostic (4.26e-2)" "unprognostic (3.64e-2)" "unprognostic (1.00e-1)" "prognostic favorable (9.96e-4)" "unprognostic (1.16e-2)" "unprognostic (4.85e-2)" "unprognostic (8.52e-2)" "unprognostic (2.29e-1)" "prognostic favorable (6.95e-4)" "unprognostic (4.99e-2)" "prognostic unfavorable (7.31e-8)" "unprognostic (1.65e-1)" "unprognostic (3.01e-1)" "unprognostic (3.58e-1)" "unprognostic (3.16e-3)" 11.4 12.1 8.3 7.4 8.5 13.0 11.3 8.4 12.8 12.9 9.1 14.2 10.8 11.2 4.0 13.3 11.5 4.3 10.2 8.3 8.1 16.6 17.7 12.0 11.0 9.4 8.5 9.3 15.8 3.3 11.4 5.3 8.9 15.3 4.0 1.6 12.0 3.0 10.0 14.6 19.7 4.4 8.3 28.6 15.6 13.3 9.1 10.3 16.0 3.2 5.8 13.5 11.8 8.8 9.5 14.2 5.1 8.6 3.5 5.7 10.0 8.2 4.7 8.5 7.6 9.1 6.8 6.9 4.5 5.5 8.0 11.8 5.3 7.3 3.8 4.1 18.7 5.7 8.1 13.0 5.4 6.0 12.8 3.4 9.1 3.8 4.2 5.9 13.4 9.7 6.7 6.7 5.3 8.4 11.2 15.7 5.7 7.5 11.6 6.9 7.1 7.4 3.3 6.1 6.7 8.5 9.7 11.1 11.5 9.9 9.1 11.3 8.0 11.2 6.6 8.5 8.3 9.4 6.5 5.5 8.3 5.3 5.7 2.4 1.2 4.0 0.8 1.6 0.5 1.2 0.5 0.6 1.3 1.8 0.3 0.4 2.1 0.4 1.0 1.4 0.8 0.8 8.3 8.5 8.4 12.8 8.3 8.1 9.4 8.5 8.9 8.3 9.1 8.8 8.6 9.6 5.5 0.0 2.9 0.0 0.0 0.0 0.0 0.0 6.9 7.1 0.0 0.0 1.3 1.8 0.0 9.9 8.8 0.0 0.0 4.7 0.0 3.2 5.8 3.0 0.0 0.0 0.0 5.3 7.2 2.5 0.0 6.2 6.3 8.6 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 6.0 0.0 0.0 3.3 0.0 0.0 2.3 2.2 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 10.5 3.9 5.1 0.0 0.0 TEX101 "CT131, MGC4766, SGRG, SPATA44, TES101RP" ENSG00000131126 "Testis expressed 101" Q9BY14 19 43401496-43418597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 117.7" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 909.7" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 5 "cerebral cortex: 21.5" "Immune cell enriched" "Detected in single" 557 "basophil: 55.7" "Lineage enriched" "Detected in single" 557 "granulocytes: 55.7" "Cell line enhanced" "Detected in single" "THP-1: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA041915, HPA042513" Enhanced "Secreted in male reproductive system" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA041915: AB_10795268, HPA042513: AB_10795507" "unprognostic (2.50e-2)" "unprognostic (5.67e-4)" "unprognostic (2.64e-1)" "unprognostic (6.89e-2)" "unprognostic (1.87e-1)" "unprognostic (5.78e-4)" "unprognostic (1.70e-1)" "unprognostic (2.84e-2)" "unprognostic (6.54e-2)" "unprognostic (4.06e-1)" "unprognostic (2.49e-2)" "unprognostic (1.67e-7)" "unprognostic (8.83e-2)" "unprognostic (2.24e-1)" "unprognostic (7.49e-2)" "unprognostic (7.04e-2)" 0.1 0.4 0.3 0.3 0.3 0.1 0.2 0.3 21.5 0.5 0.2 0.5 0.4 0.4 0.2 1.3 0.3 0.2 0.5 2.6 0.2 0.2 0.5 0.2 0.2 4.3 0.2 0.5 1.6 0.1 0.0 0.2 2.0 0.3 0.5 0.0 1.1 0.2 0.6 1.5 0.5 0.3 1.1 0.1 0.2 117.7 0.3 1.0 0.1 0.0 1.3 0.1 1.0 0.4 0.2 0.0 0.3 0.1 0.2 0.6 0.1 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.4 0.3 0.1 0.1 0.2 0.1 0.3 0.0 0.1 0.4 0.1 0.5 0.1 0.2 0.3 0.4 0.0 0.2 0.2 0.4 0.2 0.1 0.2 0.3 0.0 0.1 0.2 0.1 0.2 0.1 0.7 0.0 0.2 0.5 0.0 0.2 0.0 0.1 0.2 0.6 0.1 0.0 1.3 0.1 0.2 0.1 0.1 0.3 0.2 0.3 0.1 0.2 0.1 0.1 55.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 21.5 2.6 0.2 4.3 0.2 2.0 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.2 0.1 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 10.2 0.0 0.0 31.5 6.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 909.7 151.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TEX264 "FLJ13935, ZSIG11" ENSG00000164081 "Testis expressed 264, ER-phagy receptor" Q9Y6I9 3 51662693-51704323 "Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 374.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005002, HPA017739" Enhanced Approved Nucleoli,Cytosol "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoli, Cytosol" "CAB005002: AB_425976, HPA017739: AB_1857910" "unprognostic (2.80e-3)" "unprognostic (1.05e-2)" "unprognostic (2.69e-1)" "unprognostic (2.79e-3)" "unprognostic (8.11e-2)" "unprognostic (8.26e-3)" "unprognostic (2.05e-1)" "unprognostic (3.06e-3)" "unprognostic (2.30e-1)" "unprognostic (5.19e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.83e-1)" "prognostic favorable (7.95e-9)" "unprognostic (4.99e-2)" "unprognostic (3.65e-1)" "unprognostic (3.17e-1)" "unprognostic (4.67e-2)" 34.7 73.4 43.5 23.1 46.5 22.3 35.6 48.7 51.7 39.0 53.1 41.5 39.0 34.2 41.2 41.1 44.0 39.7 41.4 43.8 47.2 67.6 65.3 29.8 33.5 47.2 45.5 31.3 54.3 88.5 26.2 29.4 46.4 45.1 34.5 20.4 58.7 46.9 34.2 69.3 37.6 26.3 46.3 40.9 46.7 111.5 45.9 29.1 48.7 29.6 26.3 35.9 34.9 48.4 36.5 65.5 11.6 59.3 116.8 56.4 23.5 31.0 72.0 50.1 50.1 35.2 84.2 51.6 21.9 44.1 84.2 34.7 32.7 61.6 23.7 42.0 51.9 49.6 40.2 47.8 104.0 31.5 53.6 74.8 96.9 56.3 57.1 45.3 36.9 39.0 26.6 87.7 51.9 42.1 50.9 73.3 12.6 59.8 72.7 24.3 15.3 98.7 79.7 50.1 16.5 26.8 37.4 101.5 48.0 15.7 49.6 66.0 27.3 49.8 20.8 53.0 41.2 61.0 71.3 26.4 61.5 65.9 50.9 99.2 110.1 69.3 119.7 115.6 120.3 98.6 122.6 113.6 104.6 102.4 100.9 103.1 23.5 76.1 115.6 92.4 159.9 139.9 43.5 46.5 48.7 51.7 43.8 47.2 47.2 45.5 46.4 46.3 45.9 48.4 63.6 35.3 21.9 12.4 36.7 34.8 46.7 123.9 45.5 33.5 69.9 68.2 24.4 65.8 68.2 99.3 58.4 142.9 52.3 70.3 62.6 83.1 57.7 44.9 31.8 54.8 32.9 24.8 6.5 75.7 88.9 41.4 29.0 48.2 16.5 45.3 38.9 63.1 105.4 42.1 9.1 56.5 118.0 48.3 45.5 61.2 51.0 47.8 65.8 8.4 56.1 62.6 89.6 7.5 12.3 59.6 76.4 48.9 36.0 45.6 137.6 126.7 49.7 55.4 26.3 30.8 30.7 374.8 111.7 46.3 35.4 76.3 61.9 110.4 86.0 49.9 TEX46 C1orf234 ENSG00000227868 "Testis expressed 46" H3BTG2 1 23010834-23015852 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "testis: 83.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.11e-1)" "unprognostic (1.86e-1)" "unprognostic (9.04e-2)" "unprognostic (2.13e-1)" "unprognostic (1.24e-2)" "unprognostic (6.33e-2)" "unprognostic (2.84e-1)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (9.76e-2)" "unprognostic (8.12e-2)" "unprognostic (3.82e-3)" "unprognostic (2.29e-5)" "unprognostic (1.06e-1)" "unprognostic (1.15e-1)" "unprognostic (7.60e-2)" 0.1 0.1 0.4 0.0 0.7 0.0 0.3 0.3 1.5 0.2 0.0 0.0 0.1 0.2 0.7 0.4 0.2 0.0 0.1 0.5 0.5 0.1 0.1 0.2 0.0 0.6 0.6 0.1 0.2 0.1 0.2 0.0 0.5 0.2 0.0 0.7 0.0 0.0 0.1 0.7 0.0 0.0 0.3 0.0 0.0 83.2 0.7 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.1 0.0 0.4 0.1 0.9 0.2 0.4 0.0 0.1 0.3 0.2 0.0 0.2 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.1 1.1 0.3 0.1 0.2 0.0 0.2 0.6 0.2 0.1 0.2 0.3 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.4 0.1 0.1 0.1 0.0 0.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 1.5 0.5 0.5 0.6 0.6 0.5 0.3 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TEX51 ENSG00000237524 "Testis expressed 51" A0A1B0GUA7 2 126898864-126902097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 183 "testis: 59.9" "Cell type enriched" "Detected in single" 11 "Proximal tubular cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TF "PRO1557, PRO2086" ENSG00000091513 Transferrin P02787 3 133746040-133796641 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Ion transport, Iron transport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "liver: 7525.8;retina: 2433.0" "Group enriched" "Detected in many" 9 "Hepatocytes: 7205.2;Muller glia cells: 12965.3" "Cancer enriched" "Detected in many" 42 "liver cancer: 783.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 48 "Hep G2: 780.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001527, HPA005692, CAB009538" Enhanced "Secreted to blood" NA NA 19800000000000 98000000000 "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "CAB009538: AB_793365, HPA001527: AB_1080357, HPA005692: AB_1080354" "prognostic favorable (4.05e-4)" "unprognostic (2.45e-2)" "unprognostic (1.78e-1)" "unprognostic (1.50e-1)" "unprognostic (8.99e-2)" "unprognostic (5.18e-2)" "unprognostic (6.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.82e-1)" "unprognostic (3.08e-1)" "unprognostic (1.37e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (2.35e-13)" "unprognostic (2.17e-3)" "unprognostic (5.49e-2)" "unprognostic (3.47e-3)" "unprognostic (9.70e-2)" 80.9 1.2 186.3 1.0 412.5 2.4 13.3 591.8 274.2 2.0 58.9 2.3 0.9 1.7 1.4 11.0 1.4 1.9 12.1 173.7 287.7 3.4 7525.8 1.9 1.3 786.9 385.4 2.1 4.6 2.2 4.4 1.3 628.2 5.4 1.2 2433.0 55.8 1.8 2.1 4.2 1.6 1.5 484.9 2.9 1.9 14.3 398.1 1.2 2.2 2.7 3.0 1.2 2.8 862.1 1.9 1.4 1.8 1.2 5.5 3.4 0.9 1.9 2.0 1.0 0.8 3.4 1.5 1.7 1.6 1.8 1.2 2.1 1.3 1.8 1.5 1.1 0.7 16.3 2.7 780.9 1.3 4.6 2.7 2.4 3.8 1.0 1.7 1.8 2.2 0.9 6.4 2.1 2.6 1.3 1.1 1.2 1.2 1.2 1.8 1.5 2.9 1.2 1.1 3.1 1.9 1.4 2.4 2.6 7.0 1.3 1.9 1.3 2.9 2.4 1.5 1.6 1.1 1.7 3.0 1.4 2.0 1.5 1.6 0.6 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.0 186.3 412.5 591.8 274.2 173.7 287.7 786.9 385.4 628.2 484.9 398.1 862.1 0.7 16.0 32.4 36.2 11.4 1.0 5.6 0.6 0.0 101.3 5.3 4.3 2.7 117.2 22.9 0.0 91.8 0.2 0.2 0.1 1.9 0.7 5.4 0.8 1.0 16.7 0.0 56.2 34.2 1.1 0.3 3.9 0.0 0.6 17.7 1.3 87.4 7205.2 0.1 47.1 34.7 0.0 0.0 124.7 0.3 3.8 0.3 4.7 0.0 9.4 0.6 12965.3 0.0 45.2 1077.2 1.1 0.0 0.4 0.0 18.7 0.0 0.5 22.1 400.4 0.0 11.6 0.4 0.5 0.4 3.6 0.0 0.3 7.8 0.5 0.0 3.0 TFAM "TCF6, TCF6L2" ENSG00000108064 "Transcription factor A, mitochondrial" Q00059 10 58385345-58399220 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 631.4;Late spermatids: 933.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040648, HPA063684" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA040648: AB_10795635, HPA063684: AB_2685089" "unprognostic (5.30e-2)" "unprognostic (1.14e-1)" "unprognostic (6.34e-3)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.10e-2)" "unprognostic (3.40e-2)" "unprognostic (1.54e-2)" "unprognostic (3.23e-2)" "unprognostic (1.24e-2)" "prognostic favorable (2.74e-4)" "unprognostic (1.99e-2)" "unprognostic (5.39e-2)" "prognostic favorable (2.22e-5)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (6.76e-2)" 16.5 20.1 5.7 21.6 6.1 38.1 17.3 10.8 8.4 11.4 6.8 20.0 21.0 13.7 9.5 14.7 12.6 10.7 18.5 5.5 7.3 21.5 22.6 10.9 27.7 5.8 6.1 17.8 13.9 16.2 6.3 20.4 6.5 14.5 17.3 9.8 17.3 11.4 17.7 9.0 17.8 11.6 7.0 17.3 16.1 33.0 6.4 24.9 19.6 16.1 23.0 16.7 7.5 8.8 85.7 47.7 52.8 54.7 15.3 19.4 59.8 37.9 37.3 46.8 51.1 170.0 88.6 170.1 53.9 17.6 34.8 65.2 97.6 53.5 73.4 73.4 85.7 64.1 33.4 64.5 23.3 164.7 49.4 19.2 24.4 57.0 51.6 22.2 41.1 49.9 153.4 74.8 33.2 46.4 130.2 65.1 100.0 39.2 49.9 102.9 113.0 76.0 28.3 57.0 69.8 48.1 75.1 103.7 97.0 42.9 112.8 47.9 32.0 34.4 109.5 39.5 102.5 75.6 125.8 214.2 44.1 125.1 26.4 1.0 9.5 4.0 8.3 9.5 10.8 12.8 10.0 8.8 12.1 12.5 12.4 10.1 7.1 15.0 8.3 14.7 9.0 6.9 5.7 6.1 10.8 8.4 5.5 7.3 5.8 6.1 6.5 7.0 6.4 8.8 46.4 54.5 27.9 6.2 52.5 50.1 44.0 52.4 59.2 25.1 48.6 62.9 35.0 38.6 51.0 20.2 16.7 98.1 56.8 17.1 88.0 41.0 631.4 36.8 44.5 39.5 15.5 46.7 10.1 44.7 77.4 38.8 25.0 41.2 29.7 34.1 26.0 64.1 44.0 38.7 11.5 37.5 18.3 21.9 19.3 933.1 41.3 32.3 23.2 2.8 36.3 38.2 48.4 10.6 11.7 35.2 23.0 30.9 35.8 47.3 14.1 72.0 31.4 21.4 26.3 74.8 40.5 55.3 63.9 48.6 54.7 52.5 38.3 69.1 48.1 31.8 TFF1 "BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2" ENSG00000160182 "Trefoil factor 1" P04155 21 42362282-42366535 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "stomach 1: 7973.0" "Group enriched" "Detected in many" 9 "Gastric mucus-secreting cells: 12908.9;Pancreatic endocrine cells: 14603.3" "Group enriched" "Detected in many" 10 "breast cancer: 402.1;colorectal cancer: 268.3;pancreatic cancer: 805.7;stomach cancer: 744.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "MCF7: 13512.4;OE19: 5337.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002170, HPA003425" Enhanced "Secreted to digestive system" NA NA 950000 "Cluster 4: Stomach - Digestion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB002170: AB_563985, HPA003425: AB_1848260" "prognostic favorable (5.00e-4)" "unprognostic (8.81e-3)" "unprognostic (9.82e-2)" "prognostic favorable (5.67e-4)" "unprognostic (2.42e-1)" "unprognostic (1.72e-3)" "unprognostic (8.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.52e-1)" "unprognostic (6.62e-2)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (7.72e-3)" "unprognostic (1.07e-1)" 2.3 0.3 0.0 20.3 0.0 0.0 26.7 0.0 0.0 9.7 0.0 114.7 34.8 0.2 0.0 18.3 0.9 167.2 0.6 0.0 0.0 0.9 0.8 1.3 0.2 0.0 0.0 0.2 10.7 0.0 0.2 1.1 0.0 25.0 108.4 0.0 32.4 0.7 0.2 0.1 68.4 4.8 0.0 3.1 7973.0 0.1 0.0 0.2 5.3 0.0 0.2 30.6 2.2 0.0 0.0 42.7 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 0.0 16.2 5.7 0.0 1.1 0.0 1.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 13512.4 4.6 0.5 5.5 5337.9 223.4 1.7 0.0 0.2 0.0 1.4 0.3 0.2 0.0 5.0 0.0 1.3 5.0 0.1 0.0 0.0 3.5 0.1 0.0 3.6 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 18.7 0.0 6.1 5.9 0.0 0.0 432.7 197.2 0.0 564.7 12.1 35.0 0.0 0.1 3.1 601.9 0.0 245.7 0.0 1.8 0.2 3.5 430.2 0.0 0.0 821.8 3.1 5.1 12908.9 2.9 13.4 0.0 0.0 1.6 0.2 0.0 0.0 1395.6 111.9 0.0 0.0 0.0 0.0 9.2 0.0 0.0 10.3 0.0 0.0 0.0 0.0 14603.3 500.9 0.0 40.6 432.4 78.0 0.0 2.8 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.3 8.9 0.0 80.0 232.6 TFF2 SML1 ENSG00000160181 "Trefoil factor 2" Q03403 21 42346357-42350997 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 6852.1" "Group enriched" "Detected in some" 5 "Cholangiocytes: 2057.4;Gastric mucus-secreting cells: 7217.7" "Group enriched" "Detected in many" 11 "pancreatic cancer: 320.9;stomach cancer: 244.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.4;Karpas-707: 20.0;OE19: 55.4;PC-3: 145.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025834, HPA036705" Enhanced "Secreted to digestive system" NA NA 890000 "Cluster 4: Stomach - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB025834: , HPA036705: AB_2675263" "unprognostic (3.95e-2)" "unprognostic (9.87e-2)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.89e-2)" "unprognostic (5.55e-2)" "unprognostic (1.27e-9)" "unprognostic (1.99e-1)" "unprognostic (2.07e-1)" "unprognostic (1.28e-1)" "unprognostic (5.26e-3)" 1.4 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.8 0.0 6.5 1424.4 0.1 0.0 3.4 1.2 105.4 0.2 0.0 0.0 0.3 4.0 1.0 0.0 0.0 0.0 0.0 17.2 0.0 0.2 1.0 0.0 0.1 4.2 0.0 2.9 0.0 0.1 0.1 0.5 0.2 0.0 2.7 6852.1 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 35.4 0.0 0.2 0.0 1.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 2.9 0.0 2.6 55.4 145.2 1.1 0.0 8.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.1 0.0 0.0 2.7 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.3 0.0 0.0 0.0 0.0 3.6 0.5 0.2 2057.4 0.0 0.0 0.0 0.0 0.0 3.4 0.0 104.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 93.8 0.2 1.3 7217.7 0.0 0.0 0.5 0.0 6.1 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 2.9 5.4 0.0 0.6 0.0 0.0 0.0 0.0 833.8 5.5 0.0 11.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.0 0.0 0.1 11.8 TFF3 "HITF, ITF" ENSG00000160180 "Trefoil factor 3" Q07654 21 42311667-42315651 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 305.8;intestine: 355.3;salivary gland: 340.2;thyroid gland: 416.7" "Cell type enriched" "Detected in many" 10 "Intestinal goblet cells: 33890.3" "Cancer enhanced" "Detected in all" "colorectal cancer: 765.0" "Region enriched" "Detected in single" 6 "midbrain: 1.9" "Immune cell enriched" "Detected in single" 9 "eosinophil: 1.8" "Lineage enriched" "Detected in single" 18 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "MCF7: 58.7;OE19: 126.6;T-47d: 27.8;TIME: 105.0" "CAB020681, HPA035464" Enhanced Approved Nucleoplasm,Nucleoli "Secreted to blood" No NA 151000000 6500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Nucleoli "CAB020681: , HPA035464: AB_2674636" "unprognostic (2.84e-2)" "unprognostic (3.61e-3)" "unprognostic (1.07e-1)" "prognostic favorable (5.60e-6)" "unprognostic (1.28e-1)" "unprognostic (2.35e-2)" "unprognostic (2.13e-1)" "unprognostic (5.03e-2)" "unprognostic (1.58e-1)" "unprognostic (1.05e-1)" "unprognostic (3.71e-1)" "unprognostic (6.90e-2)" "unprognostic (4.31e-2)" "unprognostic (1.25e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" "unprognostic (3.86e-2)" 11.5 5.9 0.1 27.8 0.1 2.2 26.3 0.3 0.2 305.8 0.1 355.3 208.0 2.8 0.5 22.7 49.8 82.8 3.5 0.1 0.1 5.7 6.6 9.9 3.5 0.1 1.9 3.5 6.1 0.0 1.3 0.1 0.2 9.8 305.8 0.1 340.2 1.6 0.9 6.7 290.6 8.4 0.1 23.1 7.4 0.5 0.2 1.8 416.7 1.7 0.9 3.6 4.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 58.7 0.0 0.7 0.1 126.6 12.1 0.0 9.0 0.3 0.1 0.0 16.1 0.1 0.0 1.7 0.0 0.0 27.8 0.0 105.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.1 1.9 0.2 0.1 0.2 0.1 36.9 16.0 25.3 0.0 15.4 41.6 15.1 196.3 3.4 0.1 804.5 444.7 21.6 919.3 595.9 22.0 0.0 0.6 3.4 2188.7 0.0 9.4 0.5 29.3 1.4 322.8 770.9 0.0 0.0 67.8 0.7 21.5 71.4 11.4 59.2 2.0 170.3 5.8 2.1 5.0 0.0 33890.3 3263.2 3.4 42.4 9.0 2.5 2.8 96.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 1855.5 7.9 6.1 73.0 2788.7 0.1 453.2 0.1 0.0 1.1 28.2 1.0 0.3 4.3 38.6 0.8 14.9 0.6 1376.3 107.7 TFPI "EPI, LACI, TFI, TFPI1" ENSG00000003436 "Tissue factor pathway inhibitor" P10646 2 187464230-187565760 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 272.3;placenta: 191.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2284.2;Hepatic stellate cells: 872.4;Syncytiotrophoblasts: 879.2" "Cancer enhanced" "Detected in all" "liver cancer: 22.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 3.3;neutrophil: 1.3;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 6 "dendritic cells: 2.7;granulocytes: 3.3" "Cell line enhanced" "Detected in many" "HHSteC: 386.2;HUVEC TERT2: 742.5;LHCN-M2: 459.9;TIME: 451.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA005575, CAB020842" Supported "Secreted to blood" NA NA 58100000 87000000 "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB020842: , HPA005575: AB_1080290" "unprognostic (8.75e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (7.95e-2)" "unprognostic (4.99e-2)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (3.05e-1)" "unprognostic (5.63e-2)" "unprognostic (3.86e-3)" "unprognostic (9.22e-2)" "unprognostic (2.43e-2)" "unprognostic (2.72e-2)" "unprognostic (7.05e-2)" "unprognostic (3.39e-3)" "unprognostic (4.05e-2)" "unprognostic (4.49e-2)" "unprognostic (5.81e-2)" 67.5 12.6 2.6 20.5 3.4 8.2 52.3 4.9 5.8 41.5 7.4 23.3 52.5 25.7 18.5 33.3 35.6 57.6 38.5 4.1 2.2 56.3 272.3 126.7 33.3 6.8 2.5 26.5 25.0 7.1 6.1 191.2 3.9 15.7 27.4 4.5 15.0 12.8 26.8 19.8 41.8 30.7 3.7 20.7 19.2 6.9 3.6 11.1 36.2 42.8 17.7 52.9 29.8 3.2 38.9 24.7 29.3 0.8 224.3 267.7 0.7 66.0 156.3 42.7 65.1 22.6 192.6 0.7 27.3 52.7 74.7 2.1 15.9 3.6 110.3 1.9 7.6 12.3 73.8 197.3 386.2 0.9 0.4 123.1 5.1 232.8 61.9 93.4 742.5 0.7 31.2 0.7 459.9 35.4 4.6 0.7 22.9 0.8 68.8 0.3 40.2 0.3 72.9 1.4 0.3 0.5 56.7 2.1 3.5 95.8 0.7 0.2 451.4 30.6 29.0 61.4 13.5 1.1 1.7 0.4 239.4 0.6 35.4 3.3 0.2 0.2 0.2 0.1 0.1 0.4 0.1 0.0 0.2 0.5 0.2 0.2 1.3 0.5 0.1 2.7 0.1 2.3 2.6 3.4 4.9 5.8 4.1 2.2 6.8 2.5 3.9 3.7 3.6 3.2 99.2 35.3 335.5 1.3 4.4 20.8 2.9 33.5 4.6 0.6 16.1 9.1 7.0 173.0 102.5 38.6 0.0 59.5 4.8 0.5 13.7 140.0 41.5 7.3 74.2 287.1 105.0 43.1 0.7 273.1 2284.2 283.0 12.2 5.3 13.9 1.5 872.4 382.1 50.2 1.7 0.2 11.3 158.7 63.7 41.3 15.2 171.8 21.9 26.6 13.1 33.7 33.1 1.0 0.0 0.1 157.6 34.1 70.0 9.5 8.0 36.6 109.4 45.2 1.1 216.9 141.2 127.8 2.7 0.5 10.2 18.5 879.2 8.1 30.6 18.5 16.7 TFPI2 "PP5, REF1, TFPI-2" ENSG00000105825 "Tissue factor pathway inhibitor 2" P48307 7 93885396-93890753 "Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "placenta: 954.6" "Cell type enhanced" "Detected in many" "Ductal cells: 1476.3;Glandular and luminal cells: 575.6;Prostatic glandular cells: 412.6;Syncytiotrophoblasts: 2184.1" "Cancer enhanced" "Detected in all" "renal cancer: 65.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 3001.0;hTEC/SVTERT24-B: 1373.4;U-138 MG: 1245.9;U-2197: 1050.8;U-87 MG: 2051.0" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 29.7" "CAB010142, HPA049158, HPA070525" Enhanced "Secreted to extracellular matrix" NA NA 51000 "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB010142: AB_628166, HPA049158: AB_2680659, HPA070525: " "prognostic favorable (8.33e-7)" "unprognostic (2.20e-2)" "unprognostic (2.10e-2)" "prognostic favorable (5.42e-4)" "unprognostic (5.19e-3)" "unprognostic (3.98e-2)" "unprognostic (1.38e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-2)" "unprognostic (6.86e-2)" "unprognostic (7.54e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (8.53e-4)" "unprognostic (3.38e-3)" "unprognostic (3.65e-2)" "unprognostic (1.97e-1)" "unprognostic (7.91e-2)" 51.3 28.3 0.6 36.5 0.7 0.3 30.0 0.5 1.6 2.7 1.2 3.5 1.3 32.1 5.5 2.2 19.1 15.6 7.8 0.6 4.0 20.5 21.2 11.3 3.0 5.0 0.7 46.7 76.6 0.1 9.7 954.6 0.7 7.1 2.0 51.7 4.0 5.5 2.6 1.0 1.4 9.6 0.6 4.1 5.1 0.7 1.4 6.9 0.8 1.4 1.2 26.6 1.0 0.9 1.4 179.6 42.0 1.9 99.8 15.4 0.5 178.3 33.5 20.6 15.0 0.3 1.6 0.0 3001.0 47.0 43.9 18.6 1.1 216.1 24.6 2.8 1.3 0.1 10.2 0.7 545.7 0.0 0.9 9.1 10.7 1373.4 90.1 200.0 449.0 0.0 0.4 2.2 210.1 0.3 0.4 0.7 10.8 0.0 45.7 0.5 0.0 0.2 52.1 5.4 1.6 110.2 0.0 12.7 1.2 29.9 1.5 2.9 680.3 1245.9 13.2 1050.8 1.8 0.1 4.4 14.6 2051.0 0.3 140.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.7 0.5 1.6 0.6 4.0 5.0 0.7 0.7 0.6 1.4 0.9 141.3 3.2 3.9 0.0 1.2 0.6 311.3 77.9 0.6 17.5 37.2 7.9 0.5 21.5 122.9 318.2 39.6 16.1 0.6 0.0 0.0 1476.3 0.0 280.3 38.3 122.3 0.0 2.7 0.0 41.9 214.2 137.2 0.0 575.6 0.0 0.1 108.1 1.4 16.2 3.3 0.0 0.5 12.2 4.1 4.0 0.1 1.5 5.2 3.6 2.8 17.1 22.4 0.0 0.0 0.0 39.4 0.0 0.0 0.2 412.6 0.0 1.7 27.4 161.3 0.0 7.0 35.5 0.4 3.6 1.1 1.4 2184.1 4.9 0.7 0.0 35.0 TG "AITD3, TGN" ENSG00000042832 Thyroglobulin P01266 8 132866958-133134903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Thyroid hormones biosynthesis" "Hormone, Thyroid hormone" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 685 "thyroid gland: 9329.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 5.5;Cardiomyocytes: 3.0;Early spermatids: 2.3;Late spermatids: 2.2;Microglial cells: 1.9;Proximal tubular cells: 4.0" "Cancer enriched" "Detected in some" 1672 "thyroid cancer: 3072.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 2.1;HSkMC: 2.4;Karpas-707: 5.6;PC-3: 2.8;U-266/70: 2.0;U-266/84: 1.8" "Region enriched" "Detected in single" 5 "cerebellum: 1.1" "Low region specificity" "Detected in some" "CAB000077, HPA002740, CAB056155" Enhanced "Secreted in other tissues" NA NA 1600000 "Cluster 1: Neutrophils - Mixed function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB000077: , CAB056155: AB_2665573, HPA002740: AB_1080277" "unprognostic (1.18e-1)" "unprognostic (6.86e-2)" "unprognostic (7.40e-4)" "unprognostic (1.20e-2)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (7.38e-2)" "unprognostic (4.96e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-2)" "unprognostic (3.68e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (5.11e-2)" "unprognostic (3.64e-2)" 1.6 3.2 3.0 0.5 0.4 7.8 1.4 0.2 1.9 1.2 1.5 1.8 0.0 1.8 1.0 2.0 0.4 8.6 13.6 1.7 0.2 2.9 3.6 4.2 12.0 0.4 0.5 1.2 8.0 2.7 1.2 0.2 0.5 3.6 0.1 0.1 3.9 1.8 2.8 6.3 1.7 0.1 0.2 1.9 2.2 2.9 0.5 0.4 9329.0 0.0 0.6 0.6 1.7 0.5 0.0 0.0 0.0 0.0 0.5 0.7 0.3 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.4 1.7 0.6 0.0 0.5 0.0 0.7 0.0 5.6 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 2.0 1.8 0.0 0.1 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.1 0.1 3.0 0.4 0.2 1.9 1.7 0.2 0.4 0.5 0.5 0.2 0.5 0.5 0.3 0.0 0.6 0.3 0.2 0.0 5.5 0.1 0.0 0.0 0.1 0.1 3.0 0.0 1.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 2.3 0.3 0.1 0.4 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.4 0.4 0.3 0.0 0.7 0.3 0.0 0.0 0.0 2.2 0.0 0.1 0.0 1.9 0.7 0.3 0.0 0.5 0.1 0.1 0.0 0.4 0.1 0.5 0.0 4.0 0.0 0.0 0.0 0.3 0.3 0.8 0.3 0.0 0.6 0.0 0.2 1.1 0.0 1.2 TGFB1 "CED, DPD1, TGFB, TGFbeta" ENSG00000105329 "Transforming growth factor beta 1" 19 41301587-41353922 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 438.3;Extravillous trophoblasts: 452.1;Macrophages: 188.8;NK-cells: 223.5;T-cells: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000361, HPA073356" Approved Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 1290000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" Cytosol "CAB000361: AB_2201910, HPA073356: " "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (3.29e-2)" "unprognostic (4.90e-2)" "unprognostic (3.75e-3)" "prognostic unfavorable (3.38e-4)" "unprognostic (8.51e-3)" "unprognostic (5.63e-3)" "unprognostic (2.47e-2)" "unprognostic (5.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.88e-1)" "prognostic unfavorable (1.19e-8)" "unprognostic (1.65e-3)" "unprognostic (2.79e-2)" "unprognostic (6.39e-2)" "unprognostic (4.86e-3)" 39.8 28.6 10.8 39.7 10.7 82.9 25.4 11.8 9.4 53.2 9.5 31.0 14.4 45.9 7.4 52.2 27.7 18.1 35.8 9.5 15.5 35.8 14.7 63.4 34.0 24.5 14.9 17.4 14.3 11.5 18.0 32.1 17.6 31.6 8.4 0.6 21.2 19.8 8.1 29.3 37.8 21.8 18.4 88.9 20.1 8.1 19.4 16.7 20.2 8.3 25.7 44.1 45.3 17.7 57.7 87.6 3.4 0.3 41.7 35.3 10.0 81.9 64.4 25.2 15.4 40.4 30.1 57.0 88.6 110.5 26.8 30.1 17.8 54.6 11.1 76.6 17.9 199.0 18.0 50.4 47.7 54.9 119.6 45.0 17.5 50.5 32.7 138.7 135.2 21.1 108.0 116.8 27.9 42.1 43.1 79.6 9.4 12.0 52.7 44.4 13.1 85.4 46.8 20.3 0.3 6.5 23.9 0.1 15.1 32.5 1.9 36.3 170.3 96.4 77.2 20.7 91.2 74.4 31.7 36.3 90.3 106.4 16.4 1.1 0.8 3.9 0.7 1.2 0.6 0.2 0.3 0.4 0.5 0.3 0.2 0.3 2.4 0.3 0.8 0.9 0.3 0.9 10.8 10.7 11.8 9.4 9.5 15.5 24.5 14.9 17.6 18.4 19.4 17.7 55.0 0.0 0.0 3.3 120.6 44.4 36.5 64.8 38.7 0.2 14.4 9.7 2.3 4.3 17.2 16.5 0.0 5.4 438.3 1.4 0.0 12.8 1.0 5.7 18.2 63.1 0.0 28.0 1.6 17.1 452.1 34.3 14.3 5.0 64.9 20.0 71.4 2.7 141.2 0.0 2.1 1.4 22.4 136.1 158.6 1.8 12.2 188.8 23.2 30.0 105.8 0.3 223.5 0.0 0.6 45.1 16.4 18.0 156.5 32.9 0.4 9.0 9.7 0.7 39.5 13.9 78.6 3.1 8.0 40.3 18.9 55.7 221.9 4.1 0.8 31.1 TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Astrocytes: 119.1;Muller glia cells: 87.1" "Cancer enhanced" "Detected in all" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 59.6;hTERT-RPE1: 155.6;U-2 OS: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" NA Yes 4890000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA006134: " "unprognostic (7.24e-2)" "unprognostic (7.23e-2)" "unprognostic (6.32e-2)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.86e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (2.64e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (6.04e-2)" 1.5 1.2 8.2 1.1 11.6 0.1 4.0 9.2 14.9 7.1 7.1 2.4 0.6 6.5 4.5 1.8 3.9 2.0 6.4 11.5 11.1 1.4 0.6 7.8 0.6 18.5 12.7 4.6 1.8 1.1 2.1 12.9 10.7 17.0 0.9 10.5 8.5 11.2 4.8 2.1 0.7 5.1 8.4 2.6 1.2 0.9 10.0 0.4 2.6 2.1 0.8 3.0 3.0 11.0 4.0 20.2 1.8 15.1 4.3 2.1 0.0 2.9 0.4 30.1 21.2 5.5 46.7 0.0 59.6 0.2 25.8 11.1 1.2 2.3 32.0 0.1 0.2 0.0 1.7 0.0 46.7 0.0 0.0 1.9 5.3 4.1 15.8 155.6 8.1 0.0 0.0 0.0 29.6 0.3 0.0 0.0 1.6 0.0 1.8 0.0 8.8 0.0 10.1 0.0 0.3 0.1 34.8 3.9 0.7 39.7 2.9 1.1 38.3 21.3 58.4 17.9 30.7 0.0 0.1 0.1 9.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 11.6 9.2 14.9 11.5 11.1 18.5 12.7 10.7 8.4 10.0 11.0 2.2 76.9 6.3 119.1 0.5 8.7 8.7 35.3 4.0 9.9 8.4 5.8 4.1 14.3 29.8 5.5 0.0 0.4 0.2 0.0 0.0 40.2 19.3 2.1 6.7 8.1 0.0 0.0 8.6 16.9 13.9 28.8 0.0 6.8 1.3 0.9 4.2 0.0 1.4 1.7 36.0 0.0 8.2 0.6 13.2 28.0 8.1 3.2 12.4 30.0 1.0 87.1 0.0 3.5 1.0 21.5 0.0 13.9 1.2 15.0 0.0 0.8 12.3 3.0 0.0 27.7 19.7 0.3 0.8 0.6 2.8 0.5 0.5 0.8 0.0 2.1 TGFB3 "ARVD, ARVD1" ENSG00000119699 "Transforming growth factor beta 3" P10600 14 75958097-75983011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 28.8;Late spermatids: 48.9;Leydig cells: 27.1;Sertoli cells: 32.9;Smooth muscle cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "SK-BR-3: 104.6;T-47d: 75.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063582 Approved Vesicles "Secreted to blood" NA NA 44800 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA063582: AB_2685049" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (4.32e-3)" "unprognostic (1.29e-1)" "unprognostic (3.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (9.79e-2)" "unprognostic (2.83e-2)" "unprognostic (1.51e-2)" "unprognostic (5.63e-2)" "unprognostic (4.10e-1)" "prognostic unfavorable (4.01e-7)" "unprognostic (6.38e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-2)" "unprognostic (3.27e-3)" 22.2 13.0 43.4 15.8 45.8 1.0 15.6 33.5 58.4 46.6 18.4 12.8 4.1 25.5 9.6 7.7 14.5 36.6 27.9 31.2 38.4 20.5 17.6 25.7 7.2 40.9 42.3 8.0 27.7 9.9 8.3 55.4 40.0 43.6 4.8 1.8 10.8 17.9 38.6 5.0 6.6 34.3 38.9 5.3 14.1 4.5 42.2 6.5 12.3 11.0 8.8 45.8 16.2 70.1 1.1 1.5 1.1 13.4 2.1 4.3 0.4 1.0 1.5 0.7 0.7 0.8 3.4 0.1 1.0 2.8 0.4 0.9 2.9 0.7 0.3 0.8 1.5 0.1 3.5 1.5 2.7 0.6 0.9 10.2 0.4 1.0 0.4 2.3 3.2 2.7 1.5 6.3 0.8 7.0 0.8 0.8 0.4 0.8 5.3 3.3 4.2 0.7 1.2 0.6 21.9 6.3 4.3 104.6 0.8 1.5 75.2 0.5 0.8 2.0 4.5 2.1 5.8 0.8 1.3 0.4 3.6 1.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.4 45.8 33.5 58.4 31.2 38.4 40.9 42.3 40.0 38.9 42.2 70.1 8.6 0.0 2.8 5.5 0.8 4.5 1.2 2.1 1.2 0.7 15.1 6.1 3.6 0.0 3.3 1.8 4.2 0.5 1.2 1.3 0.0 0.5 16.4 2.6 9.9 10.2 0.0 0.0 1.3 1.3 0.4 28.8 0.0 2.4 0.0 0.5 7.9 0.8 0.9 0.0 3.0 2.6 6.1 0.6 4.4 48.9 27.1 0.9 10.6 1.0 0.7 2.1 3.1 5.5 4.7 0.4 0.1 12.8 0.5 20.6 1.4 0.4 4.2 3.9 32.9 13.9 24.4 0.4 1.4 2.4 3.1 1.4 1.3 1.6 0.4 0.8 TGFBI "BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1" ENSG00000120708 "Transforming growth factor beta induced" Q15582 5 136028988-136063818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Sensory transduction, Vision" "Amyloidosis, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 457.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.8;Kupffer cells: 292.9;Langerhans cells: 251.2;Macrophages: 198.9;Pancreatic endocrine cells: 590.1;Smooth muscle cells: 326.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 77.3" "Group enriched" "Detected in many" 32 "classical monocyte: 252.3;intermediate monocyte: 149.1;myeloid DC: 156.9;non-classical monocyte: 121.4;plasmacytoid DC: 324.5" "Group enriched" "Detected in all" 46 "dendritic cells: 324.5;monocytes: 252.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 2857.3;GAMG: 2417.8;HSkMC: 2675.6;hTCEpi: 1915.6;LHCN-M2: 2269.4;U-2197: 1916.3;U-87 MG: 3667.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA008612, HPA017019" Enhanced "Secreted to blood" NA NA 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "HPA008612: AB_1857970, HPA017019: AB_2669511" "unprognostic (1.05e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.38e-3)" "prognostic favorable (1.17e-4)" "unprognostic (5.21e-3)" "unprognostic (5.53e-3)" "unprognostic (4.60e-2)" "unprognostic (8.71e-3)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.42e-3)" "unprognostic (2.26e-1)" "prognostic unfavorable (7.82e-10)" "unprognostic (8.81e-3)" "unprognostic (1.73e-2)" "unprognostic (3.42e-1)" "unprognostic (1.70e-3)" 133.2 55.3 9.5 164.0 10.4 25.9 112.2 10.0 25.5 51.8 51.9 92.8 48.2 59.7 41.6 28.7 59.7 146.1 95.5 10.4 11.5 124.0 132.1 89.7 66.2 15.8 11.9 25.4 22.4 18.4 77.6 457.6 15.7 69.5 84.4 2.8 68.3 58.9 34.8 314.1 65.3 291.0 12.2 121.1 67.4 7.6 77.3 57.7 40.4 41.7 44.4 138.9 39.0 14.0 102.2 405.6 0.8 3.8 1104.3 354.4 1.5 295.1 42.9 209.9 125.1 186.4 1276.3 0.1 181.6 2857.3 2417.8 498.0 1.0 981.4 208.0 2.3 0.1 0.1 451.6 501.3 718.9 0.7 3.9 2675.6 1915.6 77.9 93.1 827.5 188.1 0.2 0.2 3.8 2269.4 4.8 0.7 0.7 13.1 5.1 0.9 0.4 24.3 3.4 96.7 8.8 1.3 0.7 473.7 15.5 3.9 452.8 3.7 110.9 745.6 1419.3 59.8 1916.3 1139.6 0.3 0.7 1.9 3667.3 0.9 1077.5 1.6 252.3 1.0 0.9 149.1 1.0 1.0 1.0 2.0 156.9 0.4 0.3 1.0 5.3 6.2 121.4 324.5 0.5 108.5 9.5 10.4 10.0 25.5 10.4 11.5 15.8 11.9 15.7 12.2 77.3 14.0 12.4 3.2 21.4 0.0 6.3 119.4 4.8 141.8 4.6 0.4 1.9 5.5 8.9 4.3 21.8 1.8 0.0 9.9 146.5 1.3 0.0 67.5 2.4 2.3 57.9 16.4 3.5 8.8 0.4 112.6 8.5 113.5 0.5 1.7 5.1 0.0 21.0 25.7 251.8 1.7 0.0 7.8 6.1 292.9 251.2 1.9 10.2 198.9 49.8 4.7 151.1 0.3 6.2 0.0 0.0 590.1 0.0 2.2 1.9 1.0 0.1 2.7 8.5 0.2 26.3 156.8 326.1 0.2 0.9 1.9 55.7 19.4 8.5 10.8 0.9 2.5 TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 128.4;Late spermatids: 101.7;Microglial cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 253.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: AB_2683144" "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" 15.9 9.9 9.8 18.2 9.3 33.7 15.4 13.2 8.9 19.4 11.8 18.8 11.7 20.6 8.8 15.0 8.5 21.7 8.2 6.8 11.3 22.6 14.8 16.3 13.8 18.4 14.5 13.0 8.3 8.5 7.6 48.8 20.0 17.1 13.4 4.7 8.3 16.8 8.7 6.2 9.3 33.0 18.0 16.5 18.4 18.3 17.5 11.2 11.2 13.2 13.6 22.5 8.4 27.9 13.7 19.5 115.5 36.1 26.2 19.3 17.4 44.1 47.8 40.7 44.9 19.9 9.3 29.7 13.4 34.6 32.1 30.4 39.6 34.1 54.0 77.1 12.3 43.9 20.7 17.8 43.2 27.2 102.8 40.2 35.4 62.8 29.5 25.2 7.4 10.9 62.4 12.1 55.4 20.3 4.0 31.0 24.7 12.2 11.5 11.0 253.1 12.5 9.9 3.8 31.1 36.2 34.3 150.2 46.4 47.3 28.1 36.6 13.6 29.8 25.5 129.3 27.3 12.1 13.4 20.0 62.5 45.9 26.2 16.2 2.4 9.5 7.8 1.6 6.7 1.6 3.3 5.8 2.0 1.2 3.2 6.2 4.9 4.3 2.0 1.4 2.4 2.2 9.8 9.3 13.2 8.9 6.8 11.3 18.4 14.5 20.0 18.0 17.5 27.9 13.5 6.4 8.8 18.9 18.9 23.6 7.4 19.9 44.3 8.0 18.9 11.7 7.6 4.3 12.8 60.7 0.0 23.0 37.3 5.0 0.0 18.8 128.4 6.4 22.7 17.6 9.6 7.4 14.2 31.2 6.7 36.0 9.2 9.3 29.9 19.5 6.4 12.7 49.4 0.0 8.6 7.3 8.2 32.4 52.5 101.7 9.6 39.7 35.6 116.2 24.3 3.1 35.0 45.8 21.1 33.8 4.2 13.5 11.9 18.4 3.6 13.8 5.0 2.0 32.9 21.8 20.9 11.0 12.7 25.6 16.2 19.4 25.4 7.6 8.3 11.5 TGFBR3 "betaglycan, BGCAN" ENSG00000069702 "Transforming growth factor beta receptor 3" Q03167 1 91680343-91906335 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 143.9;Hepatic stellate cells: 322.7;Leydig cells: 146.3;Skeletal myocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 35.2" "Group enriched" "Detected in many" 18 "NK-cells: 16.6;T-cells: 35.2" "Cell line enhanced" "Detected in many" "ASC diff: 227.2;ASC TERT1: 108.4;RT4: 57.1;U-2197: 78.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008257, CAB018971" Supported Approved Cytosol "Secreted to blood" NA NA 50000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB018971: , HPA008257: AB_1080258" "unprognostic (7.57e-2)" "unprognostic (3.67e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.36e-4)" "unprognostic (9.39e-3)" "prognostic favorable (4.84e-4)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (9.32e-2)" "unprognostic (1.07e-1)" "prognostic favorable (4.99e-4)" "unprognostic (2.46e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.14e-4)" "unprognostic (1.08e-2)" 66.3 35.2 6.9 9.2 6.8 5.0 62.1 7.6 8.0 56.6 20.4 28.8 8.2 33.9 24.2 28.5 36.6 20.0 16.2 7.6 6.7 28.2 16.6 27.3 7.2 6.0 10.1 81.5 12.3 5.9 7.1 58.5 7.8 16.4 12.5 1.5 35.0 32.7 12.8 25.0 19.7 27.4 7.9 40.0 18.1 11.0 8.0 7.7 13.2 29.4 4.2 47.3 28.6 7.8 9.9 9.4 14.1 2.4 227.2 108.4 44.6 7.1 35.3 8.1 9.9 4.4 1.4 0.1 1.7 13.0 6.4 1.4 3.6 1.0 6.2 34.1 7.6 0.0 11.1 41.2 5.0 0.3 0.1 26.3 4.7 17.8 4.0 1.3 4.2 0.0 23.6 0.7 2.4 0.2 0.1 0.1 5.9 4.6 3.2 0.5 4.8 2.1 3.2 57.1 0.7 0.0 3.4 0.2 20.4 5.8 1.2 3.7 12.7 13.5 3.5 78.0 1.7 34.8 3.3 0.0 2.8 1.9 1.7 1.2 0.0 0.0 35.2 0.2 19.4 0.0 8.7 19.2 0.0 0.0 2.7 12.7 0.6 16.6 1.4 1.2 4.5 8.1 6.9 6.8 7.6 8.0 7.6 6.7 6.0 10.1 7.8 7.9 8.0 7.8 77.6 9.6 9.7 58.8 3.1 37.6 10.0 2.3 44.3 0.3 38.2 60.1 20.7 30.0 4.2 31.3 2.1 27.5 66.7 0.5 3.9 2.0 54.3 11.2 32.8 90.5 24.0 10.7 7.7 5.1 12.0 143.9 5.1 8.1 2.5 20.5 322.7 21.0 11.8 0.0 34.0 1.9 8.2 23.2 29.4 29.8 146.3 5.2 35.6 82.4 0.7 1.2 62.8 7.5 0.9 3.3 0.4 74.4 21.3 8.5 1.4 20.9 8.3 0.2 13.1 187.2 36.5 0.8 2.2 17.2 34.1 58.0 36.9 92.2 3.7 8.0 THBS1 "THBS, THBS-1, TSP, TSP-1, TSP1" ENSG00000137801 "Thrombospondin 1" P07996 15 39581079-39599466 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion, Unfolded protein response" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 279.5;Granulosa cells: 228.3;Macrophages: 598.0;Smooth muscle cells: 283.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 15.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 2610.2;HUVEC TERT2: 2494.4;LHCN-M2: 1863.4;TIME: 3552.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 20.6" "CAB033678, HPA059756" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 16000000000 1400000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB033678: AB_793044, HPA059756: AB_2684121" "unprognostic (1.72e-2)" "unprognostic (9.55e-3)" "unprognostic (7.49e-2)" "unprognostic (3.31e-1)" "unprognostic (4.34e-2)" "unprognostic (1.03e-3)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (6.40e-2)" "unprognostic (9.16e-2)" "prognostic unfavorable (8.47e-5)" "prognostic unfavorable (8.50e-4)" "unprognostic (1.00e-1)" "unprognostic (9.25e-3)" "unprognostic (1.48e-3)" 364.3 72.5 1.7 394.0 3.7 114.7 95.1 2.1 11.3 66.7 27.3 166.4 24.8 161.3 3.5 49.1 142.6 275.2 98.3 2.2 2.1 70.9 129.4 309.2 32.3 10.8 4.4 76.3 69.1 7.0 26.8 99.0 10.8 89.8 85.6 0.4 137.3 12.0 16.2 35.4 83.5 243.6 0.9 79.8 150.5 2.2 14.3 12.0 34.0 4.3 7.1 396.3 36.2 2.1 171.9 62.7 49.0 17.8 199.4 233.9 0.7 1025.7 861.6 283.6 185.5 185.0 135.7 1.0 348.4 2610.2 54.4 621.0 2.2 516.1 145.0 43.4 0.5 46.6 35.0 46.9 44.4 0.3 13.2 524.9 37.2 237.2 535.1 1123.6 2494.4 1.6 1.5 1.7 1863.4 14.7 0.8 3.6 8.9 17.7 20.3 0.7 125.7 1.3 430.6 472.6 0.6 0.4 300.7 16.4 18.5 60.8 178.6 3.3 3552.9 972.6 221.0 1141.1 1146.6 2.4 1.8 2.0 33.0 0.8 1064.4 0.3 8.7 15.7 0.7 0.8 2.7 0.0 0.4 0.5 0.5 0.1 0.1 0.1 1.5 7.8 0.1 0.4 0.0 10.5 1.7 3.7 2.1 11.3 2.2 2.1 10.8 4.4 10.8 0.9 14.3 2.1 19.0 25.6 19.6 0.7 4.9 95.7 131.2 37.6 181.6 0.1 66.8 69.8 48.7 18.6 19.9 69.9 6.2 1.9 8.2 144.5 0.0 52.1 0.2 64.9 127.7 79.2 3.6 0.0 0.9 127.5 2.5 279.5 15.8 38.2 162.7 228.3 44.6 7.4 6.3 0.0 1.3 46.4 48.8 105.9 97.9 0.3 1.8 598.0 39.2 13.1 5.9 0.1 3.1 0.0 0.1 183.9 55.1 0.4 5.9 79.2 8.5 48.3 11.9 1.5 6.6 59.0 283.8 0.2 0.3 51.8 51.0 2.1 19.5 10.8 67.8 42.1 THBS2 TSP2 ENSG00000186340 "Thrombospondin 2" P35442 6 169215780-169254050 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 86.8;Endometrial stromal cells: 71.1;Fibroblasts: 127.7;Langerhans cells: 69.8;Melanocytes: 56.9;Oligodendrocyte precursor cells: 40.7;Oligodendrocytes: 55.8;Smooth muscle cells: 33.7;Suprabasal keratinocytes: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 250.2;ASC TERT1: 200.3;BJ hTERT+: 88.6;BJ hTERT+ SV40 Large T+: 96.3;BJ hTERT+ SV40 Large T+ RasG12V: 117.8;HSkMC: 113.2;hTEC/SVTERT24-B: 127.2;U-2197: 107.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017716, HPA044304" Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 21000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB017716: , HPA044304: AB_2678891" "unprognostic (2.85e-2)" "unprognostic (1.41e-1)" "unprognostic (5.87e-2)" "unprognostic (8.90e-2)" "unprognostic (3.64e-2)" "unprognostic (8.73e-2)" "unprognostic (2.93e-1)" "unprognostic (5.10e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-2)" "unprognostic (4.00e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (3.77e-6)" "unprognostic (2.19e-3)" "unprognostic (4.38e-2)" "unprognostic (4.16e-2)" "unprognostic (2.48e-3)" 52.9 7.9 5.5 14.8 15.4 0.0 36.2 10.9 7.7 63.1 0.2 20.4 2.5 50.0 0.7 12.0 34.7 50.4 44.2 6.5 13.1 8.3 8.2 19.8 3.3 17.1 18.2 33.2 5.6 1.7 9.5 2.2 21.4 9.7 2.4 0.1 8.2 2.5 3.4 41.1 9.2 21.3 11.3 3.3 5.4 2.3 15.0 0.6 17.0 1.8 1.2 29.1 30.8 19.3 0.2 0.0 2.5 1.1 250.2 200.3 0.0 76.8 88.6 96.3 117.8 0.4 0.0 0.1 0.1 76.1 0.2 0.1 2.4 3.2 22.5 0.0 0.0 0.0 0.0 0.0 73.1 0.3 0.0 113.2 0.0 127.2 0.0 0.2 0.0 0.0 0.0 0.1 3.7 0.0 0.1 1.7 16.3 0.0 0.6 0.0 0.1 1.1 0.0 0.4 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.7 0.0 46.1 0.4 107.6 9.3 0.1 0.7 0.0 30.6 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 15.4 10.9 7.7 6.5 13.1 17.1 18.2 21.4 11.3 15.0 19.3 3.5 6.4 0.0 6.8 0.0 86.8 1.6 0.1 1.8 0.4 2.2 1.8 5.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.2 3.1 71.1 4.6 0.0 0.0 1.2 0.0 0.0 127.7 1.1 1.4 0.0 0.0 15.4 0.0 0.3 0.0 1.7 0.0 0.0 0.0 69.8 0.3 8.1 1.2 56.9 6.5 0.0 0.2 0.0 40.7 55.8 0.5 0.0 16.1 0.0 1.9 0.0 4.4 0.0 0.2 0.0 1.0 33.7 0.0 0.4 1.2 42.3 0.1 2.1 5.5 0.0 0.9 THBS3 ENSG00000169231 "Thrombospondin 3" P49746 1 155195588-155209051 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 29 "Early spermatids: 297.1;Late spermatids: 1075.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 76.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA006293, HPA073242" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 9400000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA006293: AB_10602898, HPA073242: AB_2732223" "unprognostic (2.57e-1)" "unprognostic (1.63e-2)" "prognostic unfavorable (2.43e-4)" "prognostic unfavorable (1.44e-4)" "unprognostic (2.63e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (4.23e-1)" "unprognostic (4.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.88e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.38e-12)" "unprognostic (2.06e-2)" "unprognostic (9.41e-2)" "unprognostic (8.50e-3)" "unprognostic (2.26e-1)" 16.7 9.3 4.5 8.9 5.1 9.1 16.3 3.0 5.3 24.9 7.9 25.0 5.4 33.6 21.0 14.1 24.4 16.7 23.2 4.9 5.4 16.4 14.5 15.6 5.7 4.8 6.7 24.9 19.1 10.8 15.9 8.8 4.5 20.0 10.7 4.7 13.3 15.5 5.8 18.8 14.1 28.6 3.3 11.0 14.5 14.9 6.4 4.4 23.6 8.0 6.2 18.8 19.4 4.2 3.3 7.8 28.3 28.9 15.1 17.5 1.7 13.3 19.6 6.1 10.9 1.0 24.0 2.2 14.7 29.4 1.8 7.9 0.8 5.0 4.5 5.3 1.9 1.9 9.8 1.1 16.3 1.6 3.9 30.3 17.2 8.9 12.2 76.2 11.0 4.9 1.7 4.6 5.5 12.0 1.3 3.0 6.5 6.9 3.9 26.2 1.2 5.3 12.7 8.2 41.7 23.8 3.4 6.5 6.8 40.7 19.1 4.1 8.5 20.1 4.6 3.8 4.7 11.1 1.4 0.5 18.2 1.7 1.7 0.0 1.6 0.6 0.6 0.8 0.4 0.5 0.9 0.7 1.3 0.2 1.0 0.3 0.7 0.3 0.2 0.2 1.7 0.8 4.5 5.1 3.0 5.3 4.9 5.4 4.8 6.7 4.5 3.3 6.4 4.2 4.0 0.0 14.3 7.2 1.4 7.9 2.6 3.1 4.6 2.5 6.6 6.1 1.7 5.7 2.8 0.0 0.0 1.7 3.5 3.3 1.9 4.9 297.1 5.3 10.3 5.6 4.8 0.8 11.2 2.5 1.8 22.6 5.6 5.0 0.0 7.5 2.9 5.4 9.9 8.4 6.3 4.3 6.1 3.8 8.6 1075.2 23.3 3.7 10.6 0.0 1.9 1.5 1.0 0.0 3.2 3.7 2.9 10.1 1.4 2.3 2.7 3.8 2.6 3.7 0.0 11.8 8.1 20.8 4.8 3.7 5.3 1.4 2.2 2.4 3.4 2.2 THBS4 ENSG00000113296 "Thrombospondin 4" P35443 5 79991311-80083287 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Tissue remodeling, Unfolded protein response" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 216.7;heart muscle: 167.9;smooth muscle: 251.4;tongue: 214.6" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 493.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 46 "eosinophil: 4.5" "Lineage enriched" "Detected in single" 46 "granulocytes: 4.5" "Cell line enhanced" "Detected in some" "AF22: 3.1;THP-1: 7.0;U-2 OS: 2.8;U-266/70: 2.6" "Region enriched" "Detected in many" 8 "white matter: 85.7" "Region enriched" "Detected in many" 27 "spinal cord: 89.3" "CAB004597, HPA042426" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 510000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB004597: AB_628352, HPA042426: AB_2677992" "unprognostic (1.41e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-3)" "unprognostic (3.64e-2)" "unprognostic (9.94e-2)" "unprognostic (8.10e-2)" "unprognostic (5.64e-2)" "unprognostic (7.12e-2)" "unprognostic (1.66e-1)" "unprognostic (2.25e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-3)" "unprognostic (2.74e-2)" "unprognostic (3.98e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (3.33e-4)" 216.7 1.2 15.4 5.2 19.6 10.6 26.8 13.8 13.0 2.1 5.0 58.1 2.2 26.8 1.6 6.0 2.5 10.4 167.9 12.2 24.5 0.7 0.3 1.3 1.1 22.3 25.3 4.1 22.8 35.7 14.3 0.2 19.9 9.0 8.7 7.5 46.5 5.7 77.2 2.9 3.3 251.4 21.7 0.3 8.6 8.7 28.0 3.6 27.0 214.6 4.0 3.5 5.8 20.0 0.1 0.0 3.1 0.2 0.2 1.3 0.3 0.1 0.1 0.9 0.3 0.1 0.4 0.1 0.1 0.2 0.8 0.1 0.1 0.4 0.8 0.1 0.4 0.3 0.0 0.2 1.7 0.0 0.0 0.9 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 2.4 0.0 0.0 0.0 0.9 0.0 0.2 0.0 2.5 0.7 0.0 0.0 0.2 1.3 0.0 7.0 0.0 0.0 2.8 0.2 0.2 2.6 0.1 0.4 1.1 2.2 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 19.6 13.8 13.0 12.2 24.5 22.3 25.3 19.9 21.7 28.0 20.0 57.0 0.0 1.1 37.2 0.7 0.3 0.1 0.2 2.2 1.3 0.8 1.8 9.1 0.0 0.7 3.7 56.3 0.1 0.5 0.0 0.0 0.2 40.8 0.3 0.8 9.4 9.0 0.0 9.7 0.0 0.0 84.2 0.5 0.3 0.0 5.9 0.4 0.2 0.1 1.7 12.7 0.0 0.0 0.0 0.3 7.2 0.9 2.7 1.8 6.5 0.0 2.2 0.0 60.3 24.0 0.0 0.0 43.6 0.3 1.0 0.0 0.8 0.2 1.9 493.0 78.9 116.9 14.5 2.1 0.6 1.0 0.0 2.1 1.2 0.0 0.0 THOC3 "MGC5469, TEX1" ENSG00000051596 "THO complex 3" Q96J01 5 175917873-176034680 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 132.1;Early spermatids: 187.0;Squamous epithelial cells: 226.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042764, HPA044009, HPA045071" Approved Enhanced Nucleoplasm,Vesicles No No "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm Vesicles "HPA042764: AB_10965055, HPA044009: AB_10959603, HPA045071: AB_10959461" "unprognostic (1.13e-1)" "unprognostic (1.44e-1)" "unprognostic (1.85e-3)" "unprognostic (6.48e-3)" "unprognostic (8.60e-2)" "unprognostic (3.57e-2)" "unprognostic (3.06e-3)" "unprognostic (2.02e-2)" "unprognostic (3.41e-2)" "unprognostic (1.11e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-2)" "unprognostic (8.80e-3)" "unprognostic (3.20e-1)" "unprognostic (2.86e-1)" "unprognostic (3.16e-2)" "unprognostic (2.91e-1)" 12.0 14.5 22.0 11.4 15.9 35.1 21.4 23.0 40.6 23.1 19.1 27.0 12.5 13.4 63.2 82.9 15.1 8.0 9.3 40.2 14.9 16.3 22.2 11.9 29.1 15.5 13.3 18.8 15.3 10.0 15.9 17.4 15.9 14.6 21.1 12.1 22.5 14.9 12.6 26.5 16.2 12.2 13.2 17.7 17.5 51.3 15.4 39.2 20.5 17.6 45.5 17.4 33.5 15.9 82.1 44.7 47.0 102.7 44.1 39.3 168.0 48.4 44.6 104.5 120.4 63.5 65.2 105.6 68.3 27.9 112.6 69.2 71.6 206.0 109.7 73.5 103.3 57.3 46.2 70.7 14.6 94.6 49.2 33.3 85.9 90.0 45.2 23.3 58.3 98.0 88.1 46.5 66.9 98.7 64.0 57.9 40.1 82.3 160.3 110.7 59.3 110.4 75.2 60.7 89.5 51.4 100.0 48.5 52.5 67.4 55.3 86.1 45.1 35.9 40.8 55.6 88.2 23.2 44.1 64.4 26.7 90.1 28.5 16.5 26.9 15.1 39.3 33.5 48.4 49.6 81.7 48.9 43.1 70.6 99.7 62.4 3.9 42.3 31.5 39.8 133.6 59.1 22.0 15.9 23.0 40.6 40.2 14.9 15.5 13.3 15.9 13.2 15.4 15.9 14.9 12.8 8.6 2.0 35.8 44.5 34.1 64.5 132.1 12.3 17.7 18.0 4.0 10.0 24.4 25.8 10.4 40.8 25.1 8.1 41.1 25.1 187.0 50.2 18.4 16.1 16.8 63.9 5.2 19.2 84.3 15.2 26.5 44.9 12.0 18.8 13.9 20.3 24.6 6.7 3.7 16.3 26.4 13.2 14.9 122.0 14.6 14.3 8.8 1.9 15.4 8.9 27.8 4.5 2.0 21.9 11.6 19.2 55.9 18.4 10.4 46.8 15.8 12.0 19.7 10.6 22.8 107.9 48.3 226.5 40.9 20.0 33.3 25.0 27.7 31.1 THPO "MGDF, MPLLG, TPO" ENSG00000090534 Thrombopoietin P40225 3 184371935-184381968 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 35.4" "Cell type enhanced" "Detected in some" "Early spermatids: 2.3;Hepatocytes: 12.7;Late spermatids: 4.0;Proximal tubular cells: 9.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 6.0;Hep G2: 15.6;K-562: 2.8;RPMI-8226: 4.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 1070000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (5.57e-2)" "unprognostic (3.15e-2)" "unprognostic (1.75e-1)" "unprognostic (2.21e-2)" "unprognostic (6.20e-2)" "unprognostic (1.97e-1)" "unprognostic (1.37e-2)" "unprognostic (2.75e-1)" "unprognostic (1.00e-1)" "unprognostic (1.81e-1)" "unprognostic (8.40e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (1.40e-3)" "unprognostic (4.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.25e-2)" 1.8 2.5 5.2 0.5 3.9 0.0 1.4 4.7 4.8 3.9 2.4 0.7 0.2 3.8 1.3 0.4 2.0 0.4 1.2 4.5 2.8 4.5 35.4 0.8 0.2 3.3 2.9 2.8 1.7 0.1 0.7 0.5 3.0 1.3 0.3 0.0 0.5 0.5 1.9 0.6 0.7 1.5 3.0 1.3 0.9 3.9 2.8 0.0 0.8 0.9 0.1 0.9 1.9 3.6 0.0 0.0 0.0 0.0 0.5 0.0 2.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 15.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.3 0.6 4.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.1 1.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 3.9 4.7 4.8 4.5 2.8 3.3 2.9 3.0 3.0 2.8 3.6 0.1 0.0 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 1.6 0.1 0.0 0.0 2.2 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 12.7 0.6 0.0 1.3 0.0 0.0 0.8 0.0 4.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 1.1 0.8 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 THSD4 "ADAMTSL6, FLJ13710, FVSY9334, PRO34005" ENSG00000187720 "Thrombospondin type 1 domain containing 4" Q6ZMP0 15 71096952-71783383 "Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 103.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 106.4;Basal squamous epithelial cells: 449.0;Microglial cells: 247.3;Squamous epithelial cells: 141.5" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 45.3;BJ hTERT+: 53.0;T-47d: 43.3;TIME: 66.6;U-2197: 44.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.0" "Secreted - unknown location" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.59e-1)" "unprognostic (4.38e-2)" "unprognostic (3.14e-2)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.14e-1)" "unprognostic (7.80e-2)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (3.01e-3)" 4.8 8.4 9.8 1.6 7.8 0.0 14.7 6.1 8.6 103.7 9.5 7.0 7.9 22.2 7.8 60.3 37.0 10.9 41.6 8.5 7.2 14.2 7.0 10.3 0.9 7.8 9.1 3.1 6.4 0.7 9.7 3.6 7.6 34.0 6.9 1.2 11.4 15.0 3.0 8.5 8.7 10.3 7.0 1.9 12.0 3.1 15.9 1.6 8.8 2.5 2.5 13.3 38.5 5.9 6.0 45.3 0.8 13.0 6.7 40.2 0.2 22.0 53.0 11.2 5.8 0.3 8.7 0.0 17.7 7.8 38.5 17.0 1.8 9.1 6.8 2.0 2.0 0.0 4.4 0.0 4.3 0.0 0.0 3.0 6.7 6.7 26.6 30.5 20.7 0.0 0.0 0.5 9.2 9.1 0.0 0.1 3.9 0.1 7.8 0.0 0.7 0.8 29.5 6.0 0.7 5.5 8.8 10.9 0.0 5.0 43.3 0.1 66.6 0.2 1.0 44.4 11.8 0.0 0.3 0.0 10.4 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 7.8 6.1 8.6 8.5 7.2 7.8 9.1 7.6 7.0 15.9 5.9 1.1 19.2 9.0 6.5 0.0 13.9 106.4 11.3 449.0 3.0 48.7 43.9 60.1 58.6 7.5 5.5 6.2 0.4 0.8 16.2 1.9 18.3 7.5 19.3 13.2 9.8 3.0 0.0 17.1 1.8 0.4 12.5 2.6 31.8 0.0 0.3 6.1 12.3 0.2 0.0 19.1 6.1 0.0 0.0 2.1 16.9 17.4 1.6 8.8 247.3 0.0 0.3 0.0 8.5 6.7 13.6 11.0 74.4 1.2 94.6 29.3 0.5 11.0 0.9 0.0 16.8 6.6 0.9 1.7 141.5 10.9 0.8 3.1 42.2 13.2 29.7 THSD8 ENSG00000284491 "Thrombospondin type 1 domain containing 8" A0A1W2PP97 19 12802031-12813581 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.8" "Cell type enhanced" "Detected in single" "Breast myoepithelial cells: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: Non-specific - Mitochondria" 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 286.8;smooth muscle: 304.7;urinary bladder: 216.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.6;Excitatory neurons: 116.0;Fibroblasts: 201.9;Inhibitory neurons: 104.1;Muller glia cells: 108.1;Proximal tubular cells: 199.9;Smooth muscle cells: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 461.3;BJ: 738.4;BJ hTERT+: 832.5;fHDF/TERT166: 1330.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB068243: AB_2665687, CAB068244: AB_2665688, HPA003733: AB_1846340" "unprognostic (9.98e-2)" "unprognostic (2.71e-1)" "unprognostic (5.13e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.43e-2)" "unprognostic (1.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-3)" "unprognostic (3.38e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (2.40e-6)" "unprognostic (1.75e-2)" "unprognostic (1.90e-2)" "unprognostic (3.03e-2)" "unprognostic (1.14e-2)" 90.6 16.4 97.9 78.6 114.8 0.2 25.6 12.9 286.8 78.9 0.0 35.4 10.2 58.6 27.8 29.4 23.1 101.0 12.9 135.4 73.3 142.2 7.4 21.6 40.4 83.6 37.0 9.2 14.8 39.4 18.1 62.0 60.8 15.5 41.8 25.3 8.5 47.0 3.4 13.9 14.5 304.7 35.4 21.9 17.4 11.4 43.6 73.2 37.9 8.3 35.6 216.7 21.7 108.7 0.7 3.9 108.5 0.1 461.3 331.5 0.3 738.4 832.5 263.6 289.3 0.2 0.2 0.4 0.1 1330.6 121.9 0.9 4.3 1.1 200.7 65.1 0.0 41.5 14.4 0.0 142.7 0.0 0.2 247.5 0.0 335.6 11.6 355.2 0.3 22.6 0.0 0.6 206.5 0.1 0.6 0.1 173.9 0.0 1.4 0.5 50.7 0.3 0.1 0.2 18.1 47.9 0.1 0.4 0.2 32.9 1.0 2.1 0.0 368.6 120.9 107.3 110.1 0.3 19.7 0.4 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.9 114.8 12.9 286.8 135.4 73.3 83.6 37.0 60.8 35.4 43.6 108.7 68.2 0.0 1.8 17.3 2.1 17.7 0.3 1.7 0.0 27.2 1.6 40.0 0.9 0.0 0.0 9.2 0.0 1.9 0.2 0.0 21.5 0.9 1.0 5.1 141.6 69.2 0.0 0.0 116.0 0.0 2.6 201.9 1.5 3.2 1.3 0.0 17.5 0.1 4.0 32.0 104.1 0.0 0.0 0.0 25.0 2.7 96.3 2.7 17.8 21.5 0.0 108.1 0.0 64.3 22.7 0.4 0.0 77.5 0.1 0.3 0.0 199.9 0.0 27.5 32.9 9.3 226.6 0.3 0.6 0.2 17.6 4.0 4.5 6.2 0.0 0.6 TIAM2 STEF ENSG00000146426 "TIAM Rac1 associated GEF 2" Q8IVF5 6 154832697-155257723 "Metabolic proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;testis: 13.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 81.3;Early spermatids: 141.5;Excitatory neurons: 74.2;Late spermatids: 347.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 6.4;non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 65.7;HDLM-2: 27.8;RH-30: 43.3" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 36.9" "HPA011134, HPA013903" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA011134: AB_1858005, HPA013903: AB_1858004" "unprognostic (9.14e-2)" "unprognostic (5.79e-2)" "unprognostic (1.44e-1)" "unprognostic (6.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (4.36e-2)" "unprognostic (1.89e-1)" "unprognostic (5.74e-2)" "unprognostic (1.81e-2)" "unprognostic (1.84e-2)" "unprognostic (1.36e-2)" "unprognostic (1.38e-3)" "unprognostic (1.82e-1)" "unprognostic (8.13e-2)" "unprognostic (6.04e-2)" "unprognostic (1.05e-1)" 0.4 1.2 2.8 0.9 7.1 0.4 1.2 5.4 11.8 1.1 0.0 1.2 8.3 0.8 0.6 0.6 0.8 2.2 2.2 6.1 0.0 0.3 0.3 0.5 1.2 0.4 1.0 0.3 1.3 0.1 1.4 0.5 0.0 2.0 0.8 3.3 1.3 2.7 2.5 0.6 7.9 1.1 0.4 0.7 3.0 13.3 0.8 0.6 5.5 1.7 2.0 2.0 0.7 6.1 8.3 1.5 65.7 6.1 2.9 7.9 0.4 3.2 2.2 3.3 5.5 0.7 4.8 1.1 3.1 6.3 0.9 0.5 2.4 0.0 2.3 27.8 3.3 0.0 1.1 1.9 1.8 0.2 1.7 5.4 0.2 1.1 0.2 2.5 4.7 0.5 0.2 0.1 7.5 0.5 0.7 0.7 4.1 0.1 1.3 8.4 43.3 0.3 0.2 0.2 1.1 14.5 0.1 0.3 0.2 11.9 0.3 0.6 1.5 0.2 15.5 0.4 1.5 0.2 3.6 0.2 0.0 0.3 3.9 0.0 0.0 2.1 0.0 2.0 0.0 2.0 0.1 0.1 0.3 0.7 0.0 0.0 6.4 0.4 9.5 0.0 1.2 0.1 2.8 7.1 5.4 11.8 6.1 0.0 0.4 1.0 0.0 0.4 0.8 6.1 2.9 3.2 2.6 8.8 9.6 3.1 22.5 2.8 1.8 14.3 3.3 5.3 8.3 7.2 2.1 1.8 81.3 1.8 4.3 2.2 0.0 5.3 141.5 8.3 4.9 2.7 0.0 3.6 74.2 3.1 2.6 4.4 6.1 12.1 19.7 6.8 11.0 1.5 1.9 23.5 31.4 3.9 6.1 2.2 2.2 347.4 9.9 5.2 12.4 4.7 9.8 7.6 4.1 28.6 5.1 5.9 5.8 7.9 13.3 9.6 23.9 1.0 3.3 23.9 0.0 7.0 4.3 6.7 7.3 2.1 2.6 0.4 5.0 5.3 3.9 11.6 TIMP1 "CLGI, EPO, TIMP" ENSG00000102265 "TIMP metallopeptidase inhibitor 1" P01033 X 47582408-47586789 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 2277.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 2325.3;Hepatic stellate cells: 2681.5;Langerhans cells: 2307.7;Leydig cells: 1776.0;Macrophages: 1705.0;Peritubular cells: 1561.7;Smooth muscle cells: 2043.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 3225.4;ASC TERT1: 4323.2;fHDF/TERT166: 2762.5;HSkMC: 2960.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022360, HPA053417" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 127000000 520000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "CAB022360: , HPA053417: AB_2682142" "unprognostic (5.86e-3)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.09e-4)" "unprognostic (4.68e-2)" "unprognostic (1.81e-2)" "unprognostic (1.07e-3)" "unprognostic (4.99e-2)" "unprognostic (8.24e-3)" "unprognostic (9.12e-3)" "unprognostic (9.69e-2)" "unprognostic (9.10e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (2.90e-11)" "unprognostic (1.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (2.66e-1)" 1043.9 895.8 110.6 1713.4 110.5 122.2 253.0 114.1 329.6 630.5 160.0 228.0 68.3 342.1 237.4 130.8 570.2 1220.1 995.3 113.5 119.9 469.6 458.6 1221.2 150.4 132.9 125.2 820.8 170.1 224.1 510.7 589.3 130.1 749.1 204.0 25.9 518.6 412.7 61.8 132.4 180.0 741.1 118.9 239.9 208.9 267.7 286.5 80.3 340.0 78.9 119.7 2277.2 303.3 115.6 194.7 295.9 150.4 1850.9 3225.4 4323.2 36.4 2079.0 1728.4 632.5 514.0 118.9 360.1 1.8 269.6 2762.5 355.3 187.2 82.9 896.0 394.8 387.0 193.8 204.1 191.7 174.9 2097.2 136.6 2440.9 2960.8 227.7 1951.9 410.1 743.6 292.1 0.7 315.8 142.9 1088.6 343.1 2.5 518.0 166.8 229.8 647.9 2.5 318.3 173.8 1038.8 120.4 2.5 8.6 1243.6 8.2 276.9 277.6 15.3 257.6 284.8 943.7 1012.1 1108.3 206.3 58.8 135.0 7.4 2688.9 322.6 634.2 331.9 488.4 8.3 139.4 853.2 137.8 21.9 224.6 122.9 511.4 10.1 73.0 65.4 504.5 88.4 817.9 15.0 104.0 431.4 110.6 110.5 114.1 329.6 113.5 119.9 132.9 125.2 130.1 118.9 286.5 115.6 145.9 109.0 170.1 6.2 57.5 231.2 591.5 937.3 132.6 25.4 147.8 133.2 22.5 374.6 355.5 132.4 0.0 25.2 59.3 53.6 0.0 538.6 21.6 34.7 511.9 772.1 277.2 102.7 0.4 411.3 280.1 2325.3 53.5 66.7 491.4 163.7 2681.5 345.1 329.7 0.0 0.4 73.0 297.0 741.4 2307.7 86.9 1776.0 1705.0 512.3 6.5 289.0 141.7 73.2 8.5 0.6 802.1 42.4 1561.7 257.4 741.4 1.1 12.9 109.1 8.4 690.2 304.1 2043.5 52.8 10.6 25.8 174.7 45.0 126.5 231.9 50.5 513.7 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TIMP3 SFD ENSG00000100234 "TIMP metallopeptidase inhibitor 3" P35625 22 32801705-32863041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1663.5;Fibroblasts: 967.5;Leydig cells: 1398.6;Peritubular cells: 1934.1;Sertoli cells: 2327.1;Smooth muscle cells: 1116.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 502.6;BJ: 1173.0;BJ hTERT+: 514.7;fHDF/TERT166: 1073.7;WM-115: 893.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068391 Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "HPA068391: " "unprognostic (4.98e-2)" "unprognostic (1.77e-3)" "unprognostic (1.60e-1)" "unprognostic (8.53e-4)" "unprognostic (1.67e-2)" "unprognostic (1.05e-2)" "unprognostic (7.01e-2)" "unprognostic (3.22e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (1.90e-5)" "unprognostic (3.92e-1)" "unprognostic (1.95e-1)" "prognostic favorable (1.50e-4)" "unprognostic (2.66e-3)" "unprognostic (1.44e-2)" "unprognostic (2.55e-3)" "unprognostic (3.11e-2)" 805.5 288.7 71.7 41.4 74.9 1.1 556.9 68.7 72.6 376.1 221.0 190.4 30.5 393.3 230.4 168.1 373.9 153.5 532.8 64.3 79.2 248.0 92.0 625.1 69.5 83.2 86.7 116.2 81.1 139.5 139.1 999.5 76.0 178.8 81.2 31.7 178.7 341.1 128.1 170.3 122.1 379.6 70.3 187.2 152.1 64.1 106.2 41.1 340.1 325.9 28.8 197.4 261.1 59.5 19.6 0.0 16.9 2.7 502.6 280.6 1.0 1173.0 514.7 94.1 110.8 20.5 0.3 0.1 28.1 1073.7 3.6 18.3 3.2 48.4 135.0 0.1 14.3 147.4 23.5 52.4 197.4 0.1 59.7 47.4 120.4 166.9 9.5 3.4 0.0 0.0 0.1 0.9 44.6 1.2 0.4 5.0 2.5 0.0 0.8 0.1 3.4 0.4 2.1 97.0 12.5 16.8 24.1 0.5 322.9 266.6 0.7 1.3 0.0 7.9 25.2 245.9 19.1 0.2 0.4 0.4 232.3 0.2 893.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.7 74.9 68.7 72.6 64.3 79.2 83.2 86.7 76.0 70.3 106.2 59.5 1663.5 365.4 35.9 101.9 5.3 77.4 766.2 49.5 10.2 4.0 31.2 177.2 279.9 14.3 22.2 51.5 4.2 492.2 4.6 0.3 3.9 2.5 14.9 27.9 747.6 677.3 1.8 35.3 26.1 0.7 433.7 967.5 21.4 23.9 89.2 11.4 743.9 102.0 109.2 3.3 15.7 0.0 24.4 39.3 95.0 57.7 1398.6 28.6 76.5 116.2 0.7 146.6 0.0 52.3 0.8 0.9 0.0 1934.1 9.5 159.5 0.0 15.5 8.5 5.5 2327.1 339.2 1116.6 6.2 7.0 14.3 56.4 809.0 21.5 4.8 0.7 163.4 TIMP4 ENSG00000157150 "TIMP metallopeptidase inhibitor 4" Q99727 3 12153068-12158912 "Plasma proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 177.7;breast: 119.6" "Cell type enriched" "Detected in many" 10 "Adipocytes: 363.9" "Cancer enriched" "Detected in many" 13 "glioma: 66.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 212.9;ASC TERT1: 53.0;HSkMC: 91.9;NTERA-2: 50.7;U-87 MG: 53.6" "Region enhanced" "Detected in all" "cerebellum: 106.1" "Region enriched" "Detected in all" 9 "cerebellum: 47.7" "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.99e-2)" "unprognostic (5.14e-3)" "unprognostic (1.02e-2)" "unprognostic (2.10e-1)" "unprognostic (2.09e-2)" "unprognostic (1.97e-4)" "unprognostic (9.33e-3)" "unprognostic (4.26e-3)" "unprognostic (1.36e-1)" "unprognostic (1.74e-2)" "unprognostic (3.78e-1)" "unprognostic (6.81e-2)" "unprognostic (4.99e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (6.66e-5)" "unprognostic (2.86e-1)" 177.7 8.3 7.7 3.9 8.4 0.6 119.6 49.6 7.2 9.3 3.9 12.1 1.4 8.1 1.0 2.9 6.8 4.4 31.0 6.8 8.8 2.8 1.1 6.6 0.6 13.7 8.6 3.8 4.0 1.4 12.3 9.9 11.7 5.5 4.3 1.0 8.9 2.3 16.7 7.7 11.0 4.4 11.3 3.4 9.2 0.7 7.1 2.0 23.1 30.1 0.1 9.8 8.7 11.6 0.7 24.2 0.7 0.0 212.9 53.0 26.4 0.8 8.9 1.0 1.3 0.5 0.1 0.0 2.2 0.9 0.8 0.9 0.0 0.8 0.4 1.0 0.0 0.0 12.7 0.9 33.2 0.0 0.1 91.9 2.2 5.8 0.2 1.6 0.0 0.0 0.5 17.3 0.2 0.6 0.0 0.0 50.7 0.0 6.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 5.0 0.0 0.0 6.1 0.0 0.0 1.0 0.1 0.0 0.6 0.9 0.0 0.1 0.0 53.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 8.4 49.6 7.2 6.8 8.8 13.7 8.6 11.7 11.3 7.1 11.6 363.9 0.0 0.0 0.0 0.4 0.1 1.3 0.3 0.6 0.4 12.4 2.8 7.0 0.0 0.2 0.0 0.0 0.4 1.4 1.3 0.0 0.6 1.6 0.2 2.1 33.6 6.6 5.3 0.1 2.6 2.7 15.7 0.0 0.0 0.0 0.2 22.5 0.0 3.4 0.0 0.2 2.8 0.0 1.2 0.3 7.5 12.2 0.8 3.6 0.0 0.0 0.7 0.0 9.0 0.1 4.6 4.8 2.6 0.0 4.2 2.7 0.5 5.5 0.0 32.9 3.1 29.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 2.0 2.2 TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1235.1;Sertoli cells: 427.3;Syncytiotrophoblasts: 1946.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 87.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 322.7;CAPAN-2: 178.9;EFO-21: 403.6;HaCaT: 181.4;HBEC3-KT: 211.9;HUVEC TERT2: 173.4;TIME: 376.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048695 Approved "Secreted to extracellular matrix" NA NA 370000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA048695: AB_2680497" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-3)" "unprognostic (8.29e-3)" "unprognostic (6.02e-3)" "unprognostic (4.18e-1)" "unprognostic (6.96e-2)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.65e-6)" "unprognostic (7.42e-2)" "unprognostic (6.64e-2)" "prognostic favorable (9.64e-4)" "unprognostic (3.43e-2)" 173.7 40.8 19.0 18.5 17.7 0.9 150.5 17.9 19.9 86.8 16.4 83.2 26.7 101.8 10.7 31.0 82.4 23.9 230.7 15.2 17.9 177.7 22.7 85.7 8.5 19.6 18.3 38.8 31.0 13.2 25.3 183.6 19.8 71.2 16.5 1.0 63.8 40.6 46.6 37.0 51.6 36.5 16.4 119.6 66.4 6.2 21.2 3.8 115.1 30.6 5.3 88.4 70.2 17.1 96.6 0.2 0.0 0.5 0.8 0.2 322.7 14.9 1.9 0.7 0.4 44.5 178.9 0.2 403.6 13.4 7.0 181.4 0.2 211.9 0.1 0.7 0.1 0.1 7.3 11.5 4.5 0.1 0.5 0.2 37.9 0.0 7.6 0.1 173.4 0.1 2.4 0.4 0.0 0.0 0.7 0.6 0.9 52.6 6.1 0.4 0.1 0.4 57.0 72.6 0.4 0.5 38.0 125.6 4.2 18.8 7.5 0.3 376.6 0.3 91.6 0.7 2.8 0.4 0.5 1.6 0.2 0.2 3.3 2.0 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.8 0.4 0.1 0.1 0.1 0.0 19.0 17.7 17.9 19.9 15.2 17.9 19.6 18.3 19.8 16.4 21.2 17.1 345.4 9.6 5.8 0.7 2.7 11.0 121.5 244.1 8.0 0.0 32.0 73.0 46.7 37.1 28.6 132.4 0.0 1235.1 2.6 158.9 1.9 378.7 1.4 8.4 3.2 161.4 11.4 13.5 0.1 92.2 223.5 35.0 50.0 14.4 14.7 49.7 306.6 4.4 89.3 0.0 1.1 35.5 14.2 8.8 10.3 0.7 7.5 4.2 23.2 13.1 2.0 0.2 0.0 0.5 0.0 344.6 115.3 4.1 0.2 131.4 45.2 80.9 9.1 0.4 427.3 9.5 357.4 0.3 0.8 4.9 6.5 1946.1 3.8 2.7 59.7 219.4 TINF2 TIN2 ENSG00000092330 "TERF1 interacting nuclear factor 2" Q9BSI4 14 24239643-24242674 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 233.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059061, HPA069807" Enhanced "Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear bodies" "HPA059061: AB_2683895, HPA069807: AB_2686203" "prognostic favorable (4.96e-4)" "unprognostic (8.58e-2)" "unprognostic (1.53e-1)" "unprognostic (5.47e-2)" "unprognostic (3.20e-2)" "unprognostic (2.78e-2)" "unprognostic (4.75e-2)" "unprognostic (2.50e-1)" "unprognostic (4.70e-1)" "unprognostic (8.05e-2)" "unprognostic (1.05e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-3)" "unprognostic (2.04e-3)" "unprognostic (2.17e-1)" "unprognostic (4.78e-2)" "unprognostic (7.44e-2)" 47.2 76.4 17.6 17.3 19.1 20.1 44.0 18.9 23.6 42.2 17.7 40.7 11.5 43.7 21.0 63.2 36.1 12.8 39.4 17.6 18.4 48.5 33.5 44.1 22.7 19.5 18.6 32.2 44.6 233.5 31.9 14.2 19.5 37.9 15.7 12.8 37.6 16.2 45.2 40.8 38.4 19.4 18.8 55.8 41.8 16.3 18.7 29.2 40.7 16.1 26.6 40.9 41.4 20.0 18.4 16.4 23.2 12.2 25.1 18.5 11.8 18.3 23.1 26.3 24.5 7.1 20.0 26.7 10.3 26.1 19.0 17.5 13.2 16.5 16.5 34.1 6.7 16.8 15.1 28.5 21.6 17.9 23.1 20.5 26.0 21.1 20.0 24.5 28.9 25.0 6.7 33.1 21.5 20.0 27.0 8.8 5.4 19.3 20.1 21.9 14.8 19.5 23.7 25.8 14.2 13.2 19.1 18.0 17.0 15.3 12.9 11.4 23.3 12.2 14.9 21.0 14.6 25.2 19.5 15.1 14.8 9.9 18.6 124.6 47.8 113.7 59.7 51.1 48.1 58.7 46.5 56.2 41.1 65.1 48.3 48.4 60.2 63.5 49.3 34.9 61.5 75.8 17.6 19.1 18.9 23.6 17.6 18.4 19.5 18.6 19.5 18.8 18.7 20.0 34.6 16.0 23.0 6.2 54.5 16.8 63.8 35.7 26.7 23.0 18.4 17.7 13.5 15.7 29.3 18.4 8.4 31.8 51.1 19.2 35.2 35.1 8.1 12.8 15.7 31.4 13.1 15.8 4.1 47.2 26.5 28.1 16.8 18.7 40.5 10.0 27.8 16.5 35.5 15.2 4.1 16.3 32.6 30.1 19.7 10.7 23.6 29.9 21.4 7.5 43.3 41.8 72.1 3.5 7.5 40.5 23.8 29.7 31.5 38.9 22.0 25.4 9.5 18.8 26.3 25.8 29.9 24.3 26.2 27.4 25.1 42.3 46.5 29.4 15.6 53.0 TLCD3A "CT120, FAM57A, FLJ22282" ENSG00000167695 "TLC domain containing 3A" Q8TBR7 17 732412-742968 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 71.7" "Group enriched" "Detected in some" 5 "Extravillous trophoblasts: 20.1;Hofbauer cells: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.46e-1)" "unprognostic (6.16e-2)" "unprognostic (5.64e-2)" "prognostic favorable (3.53e-6)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "unprognostic (1.32e-3)" "unprognostic (2.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.59e-2)" "unprognostic (9.40e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (4.88e-2)" "unprognostic (1.60e-1)" "unprognostic (8.05e-2)" "unprognostic (1.39e-2)" 7.7 3.5 4.5 6.1 4.9 2.4 8.2 9.7 5.8 10.2 9.5 10.7 12.5 7.3 2.6 23.6 7.1 12.3 4.9 4.7 5.7 5.7 3.7 7.1 3.2 4.2 4.6 7.4 9.7 6.1 8.3 8.2 4.9 9.6 10.0 3.8 11.6 10.9 2.8 71.7 8.6 8.5 4.5 2.9 18.4 12.1 5.5 4.7 8.0 2.9 9.2 18.5 15.9 5.2 63.8 39.4 27.5 36.6 35.5 47.1 27.3 53.9 46.1 53.2 59.4 19.2 9.8 14.4 28.3 51.7 17.1 61.3 57.3 44.3 58.9 38.3 53.1 14.8 26.8 46.6 28.1 12.4 20.7 39.6 38.8 24.2 63.5 24.5 37.3 19.6 13.6 1.7 31.2 22.1 5.3 3.7 12.2 40.7 13.7 25.6 10.8 1.4 38.1 48.9 13.2 25.0 25.7 2.5 16.7 18.0 10.3 13.7 29.1 51.9 23.6 60.8 65.3 4.6 13.3 15.2 47.2 23.9 32.1 0.0 0.0 0.0 1.2 0.0 1.1 0.1 0.2 0.5 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.1 1.5 0.1 4.5 4.9 9.7 5.8 4.7 5.7 4.2 4.6 4.9 4.5 5.5 5.2 2.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 20.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 TLCD3B "DKFZP434I2117, FAM57B" ENSG00000149926 "TLC domain containing 3B" Q71RH2 16 30024427-30052978 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 41.7;retina: 67.9;testis: 104.8" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "glioma: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 16.7;SCLC-21H: 89.2;SH-SY5Y: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (9.31e-2)" "unprognostic (9.72e-4)" "unprognostic (7.78e-3)" "unprognostic (1.13e-1)" "unprognostic (8.06e-2)" "unprognostic (2.45e-1)" "unprognostic (1.54e-2)" "unprognostic (9.72e-2)" "unprognostic (2.60e-2)" "unprognostic (3.56e-2)" "unprognostic (1.12e-2)" "unprognostic (4.51e-2)" "unprognostic (2.40e-11)" "unprognostic (1.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.85e-2)" "unprognostic (1.09e-3)" 0.1 2.0 10.7 0.2 13.1 1.3 0.2 27.9 41.7 0.0 0.0 0.5 0.2 0.0 0.0 0.2 0.1 0.0 0.0 17.0 15.5 0.1 0.1 0.1 0.3 32.8 8.4 0.0 0.3 0.0 21.4 0.0 33.0 0.2 0.1 67.9 1.3 0.0 11.5 0.2 0.2 0.0 12.0 0.1 0.2 104.8 22.3 1.1 0.1 1.7 0.2 0.0 0.1 18.2 1.9 0.6 3.3 1.5 0.0 0.0 0.0 1.5 0.0 1.0 0.1 0.0 2.4 1.2 0.1 0.0 0.4 0.8 0.2 0.1 0.9 2.8 0.4 0.0 0.2 0.0 0.0 0.1 1.1 0.0 0.0 0.1 0.0 1.1 0.0 9.7 0.1 9.6 0.2 0.8 2.9 0.6 16.7 0.2 0.9 7.4 1.2 1.2 0.0 0.0 89.2 33.9 0.2 0.2 0.0 0.2 0.2 0.2 0.0 0.4 2.3 0.4 0.4 8.8 0.3 0.3 1.7 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 13.1 27.9 41.7 17.0 15.5 32.8 8.4 33.0 12.0 22.3 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TLE4 "E(spl), ESG, GRG4" ENSG00000106829 "TLE family member 4, transcriptional corepressor" Q04727 9 79571773-79726882 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 108.0" "Cell type enhanced" "Detected in all" "Early spermatids: 818.9;Late spermatids: 1315.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 99.9;BJ hTERT+: 98.7;BJ hTERT+ SV40 Large T+: 89.4;fHDF/TERT166: 154.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065357 Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA065357: AB_2685479" "unprognostic (6.68e-2)" "unprognostic (8.50e-3)" "unprognostic (2.13e-3)" "unprognostic (2.92e-1)" "unprognostic (1.91e-1)" "unprognostic (9.79e-2)" "unprognostic (1.24e-2)" "unprognostic (4.83e-1)" "unprognostic (2.83e-1)" "unprognostic (1.62e-1)" "unprognostic (9.94e-3)" "unprognostic (1.04e-1)" "prognostic favorable (6.94e-4)" "unprognostic (1.49e-1)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" 9.3 15.7 18.4 16.4 45.2 67.9 8.7 22.3 27.4 9.6 20.2 9.9 8.4 14.3 5.9 17.6 12.9 16.6 8.0 27.5 21.6 6.9 5.6 12.5 15.9 31.7 21.4 32.3 6.4 10.6 24.2 19.7 32.2 5.6 10.5 24.7 10.9 8.4 23.1 18.9 11.3 14.5 26.1 18.5 14.1 108.0 25.4 27.8 10.4 10.3 19.9 18.7 12.8 64.0 0.0 19.0 70.7 0.5 11.4 9.6 21.2 99.9 98.7 89.4 34.4 2.8 10.3 7.4 0.2 154.3 13.7 20.8 5.0 18.3 39.2 38.2 30.8 0.0 9.1 0.4 13.8 21.4 13.0 11.3 12.6 26.1 5.2 25.2 23.9 14.0 1.5 21.3 28.6 0.7 29.4 9.4 22.5 11.9 4.8 25.7 35.9 7.4 5.5 2.7 28.5 41.5 14.7 1.9 0.1 32.8 0.0 25.1 36.4 34.8 0.1 0.8 5.0 14.4 25.0 10.9 12.3 18.0 16.6 24.2 4.4 17.1 4.8 6.3 5.9 1.3 2.5 3.6 2.9 1.7 1.5 2.5 11.7 3.2 4.9 1.0 0.8 2.6 18.4 45.2 22.3 27.4 27.5 21.6 31.7 21.4 32.2 26.1 25.4 64.0 108.9 6.4 19.4 77.4 91.9 121.0 57.2 50.6 167.4 76.8 76.0 92.8 15.9 84.4 45.6 14.7 127.2 77.2 228.1 163.5 3.9 13.4 818.9 262.0 230.0 59.7 25.2 22.3 150.8 22.0 67.1 71.4 137.1 158.7 21.0 34.8 53.2 14.1 51.1 218.7 33.3 117.3 61.1 167.9 70.4 1315.5 105.6 101.7 42.7 77.8 75.3 31.0 88.6 301.6 381.0 31.7 207.6 46.6 152.7 37.8 122.0 18.1 50.4 290.2 72.3 280.7 83.9 38.3 146.0 140.0 90.8 65.0 141.0 86.8 96.0 99.9 TLL2 ENSG00000095587 "Tolloid like 2" Q9Y6L7 10 96364608-96513926 "Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.7;heart muscle: 3.6;tongue: 1.9" "Cell type enriched" "Detected in some" 4 "Granulosa cells: 82.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "RPTEC TERT1: 20.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.28e-2)" "unprognostic (7.54e-4)" "unprognostic (1.50e-1)" "unprognostic (3.31e-3)" "unprognostic (2.67e-1)" "unprognostic (2.14e-3)" "unprognostic (1.31e-2)" "unprognostic (3.52e-4)" "unprognostic (7.08e-2)" "unprognostic (2.50e-1)" "unprognostic (6.71e-2)" "unprognostic (3.37e-2)" "unprognostic (4.98e-4)" "unprognostic (2.90e-1)" "unprognostic (8.41e-2)" "unprognostic (1.95e-4)" "unprognostic (2.30e-1)" 0.0 0.1 1.3 0.1 1.5 0.2 0.0 0.6 1.7 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.0 0.3 3.6 1.2 1.3 0.0 0.0 0.0 0.1 2.6 1.0 0.1 0.2 0.0 0.4 0.1 2.9 0.1 0.1 0.2 0.2 0.0 0.9 0.0 0.3 0.1 2.2 0.1 0.3 0.1 4.7 0.0 0.1 1.9 0.0 0.0 0.0 2.0 0.2 0.1 0.4 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.1 0.2 0.1 0.2 0.1 0.0 2.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.6 0.1 0.1 0.4 0.0 20.1 0.0 0.7 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 0.6 1.7 1.2 1.3 2.6 1.0 2.9 2.2 4.7 2.0 0.4 0.0 1.1 0.3 0.7 0.1 0.5 1.9 0.0 0.0 0.0 0.0 5.5 1.5 1.0 0.0 0.0 2.4 0.1 0.0 0.0 0.2 6.9 0.2 0.1 1.4 0.0 0.0 1.9 0.6 0.1 2.4 1.5 0.5 0.0 82.4 0.0 0.0 0.3 0.0 5.6 1.7 2.0 0.3 1.4 5.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 1.5 18.6 0.7 0.0 0.0 1.4 0.8 1.0 0.2 0.2 0.0 0.0 0.7 0.4 0.2 2.6 0.0 0.4 3.4 0.3 0.1 0.2 0.6 TLR2 "CD282, TIL4" ENSG00000137462 "Toll like receptor 2" O60603 4 153684070-153706260 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 69.9;lymphoid tissue: 51.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 77.3;Kupffer cells: 117.2;Langerhans cells: 35.7;Macrophages: 101.8;Microglial cells: 33.7;monocytes: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 199.6;intermediate monocyte: 178.9;myeloid DC: 121.3;neutrophil: 457.8;non-classical monocyte: 121.5" "Group enriched" "Detected in all" 49 "dendritic cells: 121.3;granulocytes: 457.8;monocytes: 199.6" "Cell line enhanced" "Detected in some" "HL-60: 11.6;HSkMC: 12.5;hTCEpi: 12.7;NB-4: 11.4;RPTEC TERT1: 13.3;RT4: 16.3;THP-1: 62.0;U-937: 11.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060231, HPA071546" Supported Nucleoplasm,Mitochondria No NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Mitochondria" "HPA060231: , HPA071546: " "unprognostic (4.15e-1)" "unprognostic (3.29e-2)" "unprognostic (5.32e-2)" "unprognostic (1.52e-2)" "unprognostic (3.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.39e-2)" "unprognostic (4.24e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-2)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.87e-2)" "unprognostic (3.80e-3)" "unprognostic (1.42e-1)" "unprognostic (5.93e-3)" 26.8 11.8 4.3 51.7 4.4 69.9 12.5 4.6 7.5 7.9 7.6 4.6 3.9 3.3 11.8 5.4 8.2 16.3 6.1 4.0 5.3 5.1 11.3 39.9 8.8 9.5 5.9 2.5 8.8 3.4 4.0 11.4 7.9 4.7 3.3 1.5 17.2 12.3 1.7 3.5 4.9 11.7 7.1 35.9 5.2 1.9 7.4 3.6 3.4 3.7 15.4 23.6 4.0 10.1 7.1 0.1 0.3 0.0 1.0 2.9 0.0 0.0 0.5 0.5 0.8 3.3 0.4 0.0 0.8 0.0 0.0 6.4 0.6 0.4 0.3 0.1 0.1 0.2 0.0 0.8 0.1 11.6 0.9 12.5 12.7 0.0 0.1 0.8 0.0 0.0 0.0 0.1 0.1 0.1 0.0 11.4 0.7 0.0 2.7 0.3 0.0 0.0 13.3 16.3 0.0 0.3 0.7 0.1 3.3 0.4 0.0 62.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 11.3 1.7 48.4 199.6 1.8 0.3 178.9 0.5 0.4 1.1 0.3 121.3 1.2 1.3 0.2 457.8 5.3 121.5 1.1 0.2 76.2 4.3 4.4 4.6 7.5 4.0 5.3 9.5 5.9 7.9 7.1 7.4 10.1 1.7 6.4 77.3 0.7 1.1 1.1 1.2 18.4 1.2 0.0 9.7 2.2 1.3 2.8 19.5 3.7 0.0 0.2 0.6 0.2 0.0 5.0 0.3 1.6 0.5 2.6 0.0 3.6 0.1 3.8 0.2 1.9 2.6 4.9 3.8 0.5 1.4 1.8 17.4 0.0 0.5 0.3 0.0 117.2 35.7 1.3 0.6 101.8 1.8 33.7 68.4 0.4 1.0 1.0 0.1 3.1 0.0 0.4 1.4 3.4 1.5 1.0 7.5 0.3 13.1 0.6 5.1 0.2 1.0 1.9 1.1 0.1 2.3 0.5 0.5 2.0 TLR3 CD283 ENSG00000164342 "Toll like receptor 3" O15455 4 186069155-186088073 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Receptor, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 33.7;Early spermatids: 70.2" "Cancer enriched" "Detected in many" 4 "renal cancer: 10.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 5.5;memory CD8 T-cell: 5.9" "Group enriched" "Detected in many" 7 "dendritic cells: 2.0;T-cells: 5.9" "Cell line enhanced" "Detected in many" "ASC diff: 19.3;ASC TERT1: 20.0;BJ hTERT+ SV40 Large T+ RasG12V: 30.2;CAPAN-2: 48.4;HDLM-2: 19.3;HSkMC: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025658 Enhanced "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "CAB025658: " "unprognostic (2.13e-2)" "unprognostic (2.15e-1)" "unprognostic (7.26e-2)" "unprognostic (7.47e-3)" "unprognostic (1.10e-1)" "unprognostic (1.81e-1)" "unprognostic (6.39e-3)" "unprognostic (1.56e-2)" "unprognostic (9.28e-2)" "unprognostic (2.25e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (1.17e-1)" "unprognostic (4.72e-3)" "unprognostic (1.18e-1)" "unprognostic (4.52e-3)" "unprognostic (3.89e-2)" "unprognostic (1.83e-1)" 7.3 5.5 0.8 3.3 0.8 0.3 6.7 1.3 1.1 5.4 1.7 11.7 18.2 6.1 3.3 9.0 10.1 11.3 3.3 0.9 1.6 11.8 14.7 11.5 0.9 3.0 1.2 8.8 5.8 4.1 0.5 17.3 2.7 7.6 12.5 1.6 10.5 10.9 1.0 3.3 16.8 8.3 2.2 5.2 10.9 5.4 1.1 2.5 7.5 3.3 2.0 8.4 2.7 2.5 3.5 0.9 0.5 0.0 19.3 20.0 1.6 0.1 14.4 8.8 30.2 0.0 48.4 0.1 2.0 2.1 17.2 4.9 0.0 10.3 1.5 19.3 0.2 3.1 0.7 0.0 8.6 3.2 1.2 20.0 3.9 11.8 0.5 5.3 4.2 3.3 0.0 0.0 5.1 0.0 3.7 0.0 1.5 0.0 0.6 4.6 0.0 0.2 8.2 5.0 0.0 0.1 2.6 2.1 4.0 0.2 0.6 0.0 3.0 1.5 1.0 0.0 2.1 0.0 0.0 0.0 4.1 2.0 3.4 0.5 0.0 0.0 5.5 0.0 3.1 0.0 1.2 5.9 2.0 0.0 0.8 2.7 0.2 0.6 0.0 0.0 0.1 0.9 0.8 0.8 1.3 1.1 0.9 1.6 3.0 1.2 2.7 2.2 1.1 2.5 12.9 19.2 7.8 0.3 0.8 3.8 5.2 8.1 9.1 0.1 4.0 3.4 1.4 12.8 13.2 14.7 0.0 20.5 2.0 33.7 0.0 10.3 70.2 8.5 5.4 5.8 1.2 4.4 0.1 10.1 4.2 10.8 8.6 19.7 2.5 5.0 6.1 7.9 2.6 0.0 0.0 6.4 4.1 0.6 5.0 6.4 8.4 3.6 0.0 10.3 0.0 4.8 4.1 0.5 0.0 5.8 8.4 3.8 0.5 2.2 20.7 4.9 7.5 0.6 0.0 6.7 3.3 0.1 0.4 7.3 1.0 19.6 1.3 3.1 4.6 5.2 TLR4 "ARMD10, CD284, hToll, TLR-4" ENSG00000136869 "Toll like receptor 4" O00206 9 117704175-117724735 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Age-related macular degeneration, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 38.6;Astrocytes: 50.9;Hepatic stellate cells: 62.8;Hofbauer cells: 38.2;Kupffer cells: 106.0;Macrophages: 64.5;monocytes: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.8" "Group enriched" "Detected in many" 33 "dendritic cells: 22.4;granulocytes: 86.8;monocytes: 65.6" "Cell line enhanced" "Detected in many" "Karpas-707: 60.0;TIME: 43.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004025, HPA049174" Approved Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Golgi apparatus" "CAB004025: , HPA049174: AB_2680662" "unprognostic (1.60e-1)" "unprognostic (8.34e-2)" "unprognostic (7.22e-2)" "prognostic favorable (6.29e-4)" "unprognostic (3.39e-1)" "unprognostic (7.48e-2)" "unprognostic (8.68e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (5.18e-2)" "unprognostic (8.00e-2)" "unprognostic (9.42e-2)" "unprognostic (4.08e-2)" "unprognostic (8.63e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-2)" 31.1 11.0 12.4 25.7 15.7 22.3 12.0 11.7 8.3 6.5 1.7 6.7 4.3 5.6 1.2 4.8 4.8 10.8 8.4 10.3 17.8 6.8 16.7 16.2 13.1 12.3 14.0 6.0 2.6 2.5 2.1 23.9 12.4 4.6 7.3 2.9 6.0 3.2 3.1 3.5 5.8 10.8 14.9 32.6 4.4 1.5 14.2 3.5 5.5 12.0 7.7 13.3 2.7 10.1 0.0 0.0 25.5 0.0 11.1 23.0 0.1 10.2 17.9 2.5 1.5 0.0 2.6 3.6 0.5 26.7 7.5 0.1 0.0 2.2 3.7 0.0 0.0 5.7 5.1 0.4 8.1 19.1 0.1 14.2 0.0 5.4 0.7 22.5 31.4 0.0 0.0 60.0 29.2 0.0 0.0 2.9 3.1 2.4 1.2 0.0 28.0 19.8 0.9 28.9 0.0 0.1 6.4 0.0 1.0 2.2 0.0 10.4 43.5 1.4 18.4 0.1 4.8 0.0 0.0 0.0 0.9 19.1 15.2 64.0 64.9 21.5 0.1 57.5 0.0 1.7 0.1 0.0 22.4 0.5 0.0 0.0 86.8 0.1 65.6 0.9 0.0 25.5 12.4 15.7 11.7 8.3 10.3 17.8 12.3 14.0 12.4 14.9 14.2 10.1 38.6 0.0 5.0 50.9 2.3 0.8 0.3 0.1 0.6 0.2 3.5 1.0 2.9 2.8 2.9 0.0 0.0 0.3 0.1 1.6 0.0 0.1 0.1 3.5 29.2 31.6 0.0 1.3 0.2 0.2 0.2 11.5 1.5 6.8 15.8 1.2 62.8 1.9 38.2 0.0 0.2 2.0 0.0 106.0 8.6 0.4 0.0 64.5 1.8 26.2 54.0 8.8 2.1 7.5 0.3 0.5 6.1 0.0 0.1 0.1 0.0 0.4 3.7 1.3 6.6 5.5 4.5 0.1 0.3 0.3 0.0 0.8 0.9 3.1 1.2 3.3 TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: AB_2679957, HPA050547: AB_2681168" "prognostic unfavorable (7.49e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.71e-4)" "unprognostic (2.55e-2)" "unprognostic (7.02e-2)" "unprognostic (2.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (2.43e-3)" "unprognostic (4.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (8.61e-2)" 20.2 24.4 15.6 15.9 17.3 13.1 19.8 18.2 22.2 19.7 24.4 15.7 18.0 18.4 26.5 16.5 17.4 23.1 19.5 17.5 18.6 32.9 29.8 20.6 17.7 16.5 17.4 22.0 13.9 23.6 15.9 33.8 17.6 22.2 16.3 17.1 17.8 22.1 15.6 18.5 16.2 17.8 17.2 22.3 19.6 27.6 18.0 11.8 26.4 17.6 15.2 20.0 16.6 19.7 35.7 56.5 25.7 35.7 58.8 39.0 35.4 73.8 44.9 54.6 49.1 43.4 30.0 12.5 56.7 54.9 61.5 37.8 27.5 44.5 59.0 15.0 21.7 28.6 32.3 47.3 51.8 8.6 35.3 47.9 42.8 43.1 20.9 40.0 71.1 21.2 32.2 35.7 73.5 22.1 21.3 28.9 32.6 53.2 22.0 17.8 33.2 21.0 62.2 27.9 8.6 16.9 28.2 19.5 37.8 45.1 48.1 17.9 64.6 44.0 33.0 64.9 37.7 24.9 59.1 21.9 33.6 19.4 31.6 64.5 28.5 27.3 29.7 34.2 33.3 24.9 35.1 33.0 30.4 26.2 33.1 32.0 7.9 33.0 29.8 60.5 41.8 35.3 15.6 17.3 18.2 22.2 17.5 18.6 16.5 17.4 17.6 17.2 18.0 19.7 30.4 12.8 14.7 3.9 13.8 35.1 56.9 64.3 20.5 25.1 22.5 25.1 17.7 32.9 44.5 51.5 20.9 91.3 28.2 12.9 29.4 59.9 62.2 24.1 33.3 36.0 10.3 5.9 7.6 38.4 98.2 38.6 17.3 25.8 22.2 44.3 58.2 38.4 218.5 23.5 9.2 12.6 40.7 33.6 33.9 46.6 36.1 40.6 26.6 7.5 70.8 45.4 15.5 6.0 5.4 74.9 19.4 24.8 14.5 52.5 35.1 61.4 29.4 34.0 0.0 25.4 26.5 60.8 58.1 16.3 15.5 79.9 17.8 39.3 16.7 48.5 TM2D3 "BLP2, FLJ22604" ENSG00000184277 "TM2 domain containing 3" Q9BRN9 15 101621444-101652391 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054064 Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA054064: AB_2682366" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.55e-3)" "unprognostic (1.15e-1)" "unprognostic (8.37e-2)" "unprognostic (2.29e-1)" "unprognostic (8.62e-2)" "unprognostic (2.51e-2)" "unprognostic (5.40e-2)" "unprognostic (4.09e-2)" "unprognostic (1.06e-1)" "unprognostic (3.14e-2)" "unprognostic (2.92e-2)" "unprognostic (2.63e-1)" "unprognostic (3.78e-2)" "unprognostic (2.78e-2)" 32.2 38.3 58.9 23.5 62.8 28.2 33.9 57.0 74.7 36.7 51.4 31.1 24.6 40.8 43.5 23.9 34.2 29.6 47.8 62.0 70.1 32.2 58.1 28.1 30.5 54.9 58.7 55.7 30.3 40.6 35.7 31.7 58.5 32.7 24.2 32.3 34.4 35.3 44.5 27.0 26.2 32.1 55.9 29.2 29.1 28.0 61.1 29.5 45.2 55.7 31.7 32.8 28.5 58.0 20.1 48.9 25.6 46.6 71.9 53.1 31.3 25.9 42.6 30.0 33.4 26.4 55.5 32.5 34.9 35.5 50.7 45.9 40.3 33.3 23.7 31.2 88.4 48.7 39.9 45.4 47.2 38.4 55.8 44.2 66.3 18.1 37.4 42.1 42.1 41.5 40.6 47.8 47.9 40.8 28.3 40.2 39.5 90.4 16.2 33.9 32.3 51.0 61.5 52.0 34.3 31.3 35.8 37.4 54.3 43.7 35.5 49.8 33.7 31.6 32.5 21.2 28.9 45.0 71.2 35.3 26.9 47.5 26.7 36.4 40.6 81.9 41.2 41.9 46.4 30.6 33.6 31.6 29.1 44.8 44.1 41.4 69.6 52.4 32.4 24.6 38.4 41.3 58.9 62.8 57.0 74.7 62.0 70.1 54.9 58.7 58.5 55.9 61.1 58.0 52.4 25.6 28.7 22.2 55.8 66.3 58.5 142.3 32.5 47.1 42.6 45.8 35.7 35.8 67.9 42.3 33.3 73.7 51.9 23.0 19.6 61.0 8.0 28.1 38.2 48.8 27.0 30.3 41.5 42.3 64.7 53.7 23.0 44.8 25.3 37.6 60.3 56.6 32.3 69.0 55.3 23.2 91.6 42.1 36.4 10.8 73.7 39.2 26.6 37.5 44.4 60.6 56.7 29.1 45.8 27.8 20.7 62.8 41.3 66.6 32.6 39.5 47.2 46.8 72.3 40.1 67.0 89.3 84.2 25.0 55.4 91.0 55.1 21.5 27.8 40.0 TM4SF19 ENSG00000145107 "Transmembrane 4 L six family member 19" Q96DZ7 3 196319342-196338503 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 6.0;testis: 4.6" "Cell type enriched" "Detected in some" 8 "Hofbauer cells: 74.6" "Group enriched" "Detected in some" 4 "cervical cancer: 1.4;head and neck cancer: 3.4;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 0.9" "Region enhanced" "Detected in single" "thalamus: 2.5" "Group enriched" "Detected in some" 6 "gdT-cell: 14.8;memory CD8 T-cell: 3.9;naive CD8 T-cell: 4.9" "Lineage enriched" "Detected in single" 16 "T-cells: 14.8" "Cell line enriched" "Detected in many" 12 "GAMG: 427.6" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 71: Testis - DNA repair" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (9.90e-2)" "unprognostic (1.17e-2)" "unprognostic (3.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.67e-1)" "unprognostic (7.19e-2)" "unprognostic (8.90e-5)" "unprognostic (8.86e-3)" "unprognostic (1.30e-1)" "unprognostic (3.21e-2)" "unprognostic (1.85e-1)" "unprognostic (2.86e-1)" "unprognostic (1.06e-3)" "unprognostic (4.23e-2)" "unprognostic (4.20e-3)" "unprognostic (2.60e-1)" "unprognostic (1.18e-3)" 6.0 0.3 0.1 0.5 0.2 0.6 2.9 0.3 0.5 1.5 0.0 0.3 0.2 0.3 0.0 3.4 0.3 0.1 0.1 0.2 0.1 0.2 0.5 3.5 0.5 0.1 0.2 0.7 0.3 0.0 0.1 0.8 0.4 0.5 0.2 0.5 1.5 0.0 1.6 1.8 0.2 0.1 0.2 0.6 0.5 4.6 2.5 0.2 0.7 0.5 0.7 0.3 1.7 0.8 15.6 7.2 0.2 0.4 0.9 4.6 0.3 0.0 4.4 1.6 2.9 0.0 8.2 0.2 2.6 0.0 427.6 2.2 0.0 1.7 1.1 0.6 0.0 0.3 2.1 0.0 1.0 0.5 0.4 0.5 1.4 18.8 31.3 0.0 0.0 0.9 9.8 0.9 4.8 1.2 0.1 0.8 0.0 0.2 36.2 0.2 3.2 0.9 0.0 0.4 0.3 0.0 2.5 0.1 0.7 0.4 0.6 0.2 1.4 18.6 15.6 2.9 9.1 0.5 5.6 0.3 20.2 0.7 0.3 0.9 0.3 0.4 14.8 0.4 0.1 0.1 1.3 3.9 0.1 0.3 0.7 4.9 0.6 0.7 0.1 0.6 0.4 1.6 0.1 0.2 0.3 0.5 0.2 0.1 0.1 0.2 0.4 0.2 2.5 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 2.9 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 74.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 9.3 4.9 4.9 0.0 0.4 0.9 0.1 0.0 0.0 TM7SF3 ENSG00000064115 "Transmembrane 7 superfamily member 3" Q9NS93 12 26971579-27014434 "Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 258.0" "Cell type enhanced" "Detected in all" "Late spermatids: 148.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 553.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057640 Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA057640: " "unprognostic (4.24e-1)" "unprognostic (1.90e-2)" "unprognostic (1.04e-3)" "unprognostic (8.80e-2)" "unprognostic (5.82e-2)" "unprognostic (5.10e-2)" "unprognostic (1.83e-1)" "unprognostic (5.79e-2)" "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (1.01e-2)" "unprognostic (1.16e-1)" "prognostic favorable (1.32e-4)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" 38.0 48.8 23.1 28.2 25.1 66.0 33.2 19.2 27.3 37.8 34.6 60.5 40.4 29.9 48.6 61.2 40.7 58.3 18.3 23.1 25.2 258.0 138.4 53.7 29.1 25.8 22.8 32.9 117.9 42.4 20.1 36.0 24.6 36.1 69.1 38.9 41.6 43.9 13.7 40.5 35.3 45.8 26.1 32.7 48.7 30.6 26.3 101.4 44.0 35.4 39.9 47.5 28.6 30.7 70.0 147.8 82.6 104.7 122.1 74.3 438.7 74.3 132.8 65.1 109.9 73.3 289.2 80.9 92.3 78.1 61.1 71.5 85.9 553.0 77.0 84.1 46.7 126.9 168.2 134.1 76.7 439.5 84.9 48.7 382.6 144.3 111.7 191.8 177.2 242.2 53.8 60.1 97.1 114.9 232.4 189.3 170.5 266.8 75.4 216.9 131.8 164.2 93.7 278.2 14.4 72.9 84.8 56.6 121.0 391.6 151.8 77.2 62.4 53.9 92.1 140.3 93.4 38.5 97.3 152.9 115.5 133.7 78.5 11.2 7.4 19.0 6.0 8.1 5.4 8.7 8.0 7.8 12.4 13.5 11.1 7.1 6.2 13.7 3.8 10.1 13.9 4.7 23.1 25.1 19.2 27.3 23.1 25.2 25.8 22.8 24.6 26.1 26.3 30.7 23.2 12.8 27.6 28.4 20.2 28.8 52.4 78.7 96.8 50.0 17.2 19.8 10.3 127.2 46.0 42.3 43.8 40.0 35.2 22.2 17.6 62.1 82.4 23.0 5.7 19.4 13.2 49.0 83.1 39.6 15.2 23.5 32.1 21.1 14.0 48.5 22.5 42.5 39.5 23.5 50.4 24.0 28.5 25.7 11.1 148.8 15.5 27.1 65.8 26.2 27.4 30.8 27.8 63.8 40.0 25.3 28.1 23.0 38.2 18.1 25.5 143.7 24.9 38.4 6.6 27.4 18.4 10.1 22.3 65.0 27.8 16.3 21.8 21.6 31.3 37.6 TM9SF1 "HMP70, MP70" ENSG00000100926 "Transmembrane 9 superfamily member 1" O15321 14 24189149-24195687 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA059249 Supported Approved "Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA059249: AB_2683959" "unprognostic (3.27e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (9.31e-2)" "unprognostic (1.48e-1)" "unprognostic (3.84e-2)" "unprognostic (1.19e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.62e-3)" "unprognostic (2.44e-1)" "unprognostic (4.24e-1)" "unprognostic (2.20e-1)" "unprognostic (4.18e-3)" 28.0 35.2 7.5 10.5 7.6 3.7 25.6 7.9 7.9 29.2 18.2 23.9 12.7 31.1 31.3 25.4 27.9 17.5 21.7 7.4 7.7 25.1 34.6 26.7 7.7 8.8 9.4 24.8 46.8 36.6 20.0 18.1 8.4 23.4 15.5 5.9 35.6 21.3 19.5 24.2 21.4 18.1 8.5 19.4 29.4 20.2 8.3 8.3 30.7 11.1 12.4 23.8 23.6 8.4 22.0 45.1 17.7 18.0 59.4 40.4 22.4 37.6 55.4 53.7 60.5 19.1 49.0 12.5 25.2 50.3 30.7 50.5 14.9 29.7 39.3 18.4 15.4 9.4 21.3 56.2 41.8 18.5 22.8 41.3 56.1 36.9 50.5 42.3 32.3 7.9 11.2 30.7 43.6 51.2 12.1 15.7 8.4 62.1 39.2 15.6 22.1 24.7 42.5 37.9 16.3 18.6 39.0 44.3 24.5 16.8 28.8 14.1 26.0 47.5 21.2 23.1 28.1 31.0 25.5 7.4 18.1 11.5 39.5 33.4 20.5 25.0 14.1 18.1 15.3 15.0 14.6 12.6 23.4 16.3 13.0 12.9 28.3 23.1 18.5 39.2 17.2 13.5 7.5 7.6 7.9 7.9 7.4 7.7 8.8 9.4 8.4 8.5 8.3 8.4 5.5 16.0 5.3 8.8 11.2 3.3 6.1 7.3 18.8 4.4 6.1 5.0 1.5 7.2 7.6 1.8 14.6 9.8 5.0 4.0 0.0 8.2 13.9 5.2 7.4 8.7 1.8 5.5 6.6 4.9 10.4 14.9 13.7 6.3 2.5 5.3 5.0 4.8 4.1 0.0 7.1 3.5 6.1 2.5 4.5 6.2 5.3 5.6 1.8 4.7 5.3 5.4 4.1 9.0 7.3 5.3 6.1 4.5 54.3 7.7 3.5 3.0 30.0 7.6 6.6 10.1 7.4 7.0 5.4 19.5 4.7 11.9 9.1 5.7 4.1 3.8 TMBIM6 "BAXI1, BI-1, TEGT" ENSG00000139644 "Transmembrane BAX inhibitor motif containing 6" P55061 12 49707725-49764934 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1803.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 2394.6;Late spermatids: 2375.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017378 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "HPA017378: AB_2669604" "prognostic unfavorable (3.54e-4)" "unprognostic (6.25e-2)" "unprognostic (1.90e-2)" "unprognostic (6.52e-2)" "unprognostic (8.46e-3)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (1.22e-2)" "unprognostic (6.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.80e-1)" "prognostic favorable (1.00e-5)" "unprognostic (1.95e-1)" "unprognostic (9.27e-2)" "unprognostic (1.28e-1)" "unprognostic (1.54e-2)" 333.4 364.8 332.1 276.3 361.6 315.4 416.8 347.5 376.4 413.7 528.2 493.6 475.8 252.3 640.9 406.3 431.1 360.3 215.5 301.1 358.3 1144.5 1803.2 423.3 292.3 374.4 346.9 281.2 574.2 577.5 133.7 303.1 378.7 383.2 494.4 305.0 479.8 409.3 232.1 231.4 536.1 294.7 351.9 267.8 549.8 247.9 366.9 313.0 596.4 232.3 332.3 406.2 216.5 395.2 609.6 516.6 413.3 381.1 1169.3 645.1 513.6 450.2 854.0 572.0 519.7 837.6 1703.8 380.3 746.9 882.6 598.6 648.1 363.7 659.4 619.2 551.7 390.3 606.2 367.8 414.0 707.7 701.9 959.4 657.5 1511.3 640.9 925.8 809.3 481.6 461.0 556.2 1526.5 662.5 589.5 362.1 424.2 432.1 730.6 392.2 302.8 413.0 651.0 871.5 909.9 319.0 208.7 603.5 786.1 511.2 530.7 989.4 731.6 456.8 522.6 393.9 355.8 396.9 654.2 717.8 326.8 730.9 324.3 260.8 896.4 749.8 795.5 559.9 721.8 587.8 403.6 501.1 558.5 585.5 356.6 438.9 501.8 1242.0 463.8 769.5 587.0 544.8 1813.1 332.1 361.6 347.5 376.4 301.1 358.3 374.4 346.9 378.7 351.9 366.9 395.2 428.2 477.5 455.5 80.6 314.2 261.0 535.0 836.9 222.5 245.8 526.8 337.6 221.0 571.9 766.5 544.4 114.7 406.9 366.7 995.8 131.0 927.3 1504.8 340.5 240.0 321.9 294.9 232.7 43.9 816.9 913.0 336.0 325.7 501.9 257.7 194.5 358.7 2394.6 618.9 180.0 57.3 612.6 598.1 570.6 292.8 2375.1 288.6 458.2 247.3 58.1 540.3 467.7 285.3 94.5 115.5 846.7 651.3 287.3 589.8 550.0 1585.8 809.6 874.1 154.8 170.9 191.7 361.1 458.1 214.7 272.7 235.0 891.0 315.9 372.8 552.2 654.4 TMCO6 "FLJ39769, PRO1580" ENSG00000113119 "Transmembrane and coiled-coil domains 6" Q96DC7 5 140639435-140645408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037473, HPA037474" Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 14: Monocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA037473: AB_10671049, HPA037474: AB_10671050" "unprognostic (1.03e-1)" "unprognostic (3.40e-1)" "unprognostic (3.95e-2)" "unprognostic (1.38e-2)" "unprognostic (6.10e-3)" "unprognostic (1.31e-2)" "unprognostic (1.65e-1)" "unprognostic (2.11e-1)" "unprognostic (4.89e-2)" "unprognostic (1.69e-1)" "unprognostic (2.75e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (7.21e-2)" "unprognostic (1.77e-1)" "unprognostic (1.96e-2)" "unprognostic (1.20e-2)" 6.6 10.5 5.7 3.9 5.7 2.9 6.6 5.5 5.8 6.1 5.5 4.9 2.9 4.8 3.4 7.2 6.9 2.9 3.1 5.5 5.8 6.7 13.3 3.6 4.6 6.0 5.9 7.1 6.6 4.0 4.9 5.6 5.9 4.8 2.5 0.7 9.8 2.9 3.6 5.2 4.8 3.0 6.3 7.2 5.2 10.4 5.9 7.7 5.3 2.6 4.0 5.4 5.6 7.0 3.9 7.5 5.0 7.4 4.9 5.2 18.1 3.0 3.4 3.8 4.1 11.6 7.2 15.6 7.8 2.3 4.4 7.7 4.2 8.8 2.0 5.5 13.7 11.9 3.7 8.3 6.5 6.7 4.4 8.6 2.3 4.6 7.7 2.9 8.9 12.6 5.1 5.0 4.7 7.5 15.3 15.5 5.7 9.2 11.3 13.1 10.3 15.5 4.6 3.5 8.6 3.7 8.6 16.6 8.0 3.4 13.6 7.9 4.2 0.1 3.7 1.4 1.3 8.4 5.7 7.4 2.4 10.7 4.6 11.6 6.5 5.7 5.2 9.1 5.7 7.8 6.9 5.1 6.9 6.1 9.5 3.9 12.7 4.4 10.3 1.9 8.2 4.1 5.7 5.7 5.5 5.8 5.5 5.8 6.0 5.9 5.9 6.3 5.9 7.0 4.0 6.4 2.0 1.3 7.5 1.9 7.3 3.4 6.8 5.2 4.6 4.3 0.6 5.7 2.4 11.0 6.2 7.7 4.2 3.9 0.0 3.8 4.1 2.2 4.0 6.3 7.3 10.3 3.8 2.4 7.4 4.6 6.6 2.5 0.0 4.6 10.0 9.7 4.8 0.0 3.3 5.0 4.1 5.1 2.7 1.5 4.1 4.1 1.8 9.4 6.6 3.3 16.5 1.0 3.9 4.5 5.2 4.9 7.3 7.4 6.2 2.4 6.2 4.3 6.6 3.9 3.4 19.2 15.8 10.3 2.3 6.3 8.2 7.7 7.7 6.9 TMED1 "Il1rl1l, IL1RL1LG, MGC1270, p24g1, p24gamma1, ST2L" ENSG00000099203 "Transmembrane p24 trafficking protein 1" Q13445 19 10832067-10836318 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 146.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018507 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 38: EFO-21 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "HPA018507: AB_1858063" "unprognostic (6.98e-2)" "unprognostic (3.42e-1)" "unprognostic (3.03e-3)" "unprognostic (1.28e-1)" "unprognostic (8.65e-2)" "unprognostic (2.27e-1)" "unprognostic (1.98e-2)" "unprognostic (4.20e-2)" "unprognostic (9.86e-2)" "unprognostic (7.27e-2)" "unprognostic (9.52e-2)" "unprognostic (4.93e-2)" "prognostic favorable (8.66e-5)" "unprognostic (9.49e-2)" "unprognostic (2.56e-1)" "unprognostic (5.16e-2)" "unprognostic (2.45e-2)" 23.6 31.2 13.4 15.4 15.3 21.6 25.1 15.6 17.3 30.0 24.9 19.5 18.9 25.0 16.3 19.9 24.8 18.8 42.3 13.0 16.9 37.8 51.9 19.6 14.3 16.6 15.1 34.4 34.5 24.4 35.9 21.4 15.5 26.5 8.1 4.4 24.2 14.8 64.4 19.1 17.4 10.6 15.2 22.3 26.2 20.2 14.5 10.2 28.7 34.9 7.0 22.3 21.0 17.4 40.4 63.3 26.7 43.6 26.2 28.5 27.8 63.3 53.0 59.0 82.3 59.2 57.2 29.1 146.5 46.0 30.8 32.2 18.8 33.4 23.6 44.2 38.5 41.5 49.8 48.5 35.4 35.2 91.4 42.2 35.1 34.9 24.9 25.8 37.4 22.3 30.3 80.6 25.3 63.9 25.4 38.0 41.3 23.6 60.5 27.8 22.9 44.6 35.0 33.3 29.5 29.0 37.6 37.0 33.9 11.2 43.8 38.5 41.5 75.1 34.4 80.3 71.6 48.9 56.6 27.8 58.1 63.5 41.6 12.3 94.6 44.3 59.3 94.0 40.9 50.9 39.9 48.6 81.1 42.2 36.6 40.5 35.7 122.8 103.0 59.9 38.9 66.0 13.4 15.3 15.6 17.3 13.0 16.9 16.6 15.1 15.5 15.2 14.5 17.4 20.2 9.6 15.3 4.6 16.5 18.5 24.4 53.9 12.0 10.2 31.8 32.0 0.2 41.5 33.0 53.3 8.4 111.5 24.5 22.7 41.1 54.4 5.5 30.9 26.7 26.4 23.5 30.7 1.0 44.2 94.0 38.1 15.8 21.7 27.3 43.7 24.3 43.9 52.5 5.0 1.2 21.1 46.8 20.2 16.6 6.3 22.4 20.0 42.7 1.0 25.0 40.3 28.8 4.0 3.2 41.7 35.5 20.3 24.4 35.4 37.7 57.4 42.9 18.0 32.9 28.9 27.1 21.7 30.9 14.8 17.5 146.3 15.1 62.3 28.8 23.3 TMED2 "P24A, p24b1, p24beta1, RNP24" ENSG00000086598 "Transmembrane p24 trafficking protein 2" Q15363 12 123584533-123598582 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014060 Approved Supported Vesicles NA NA 82000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA014060: AB_1856389" "unprognostic (6.36e-2)" "unprognostic (3.38e-3)" "unprognostic (5.41e-3)" "unprognostic (1.75e-2)" "unprognostic (2.98e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.57e-3)" "unprognostic (2.20e-2)" "unprognostic (4.31e-2)" "unprognostic (9.76e-3)" "unprognostic (1.03e-2)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.35e-7)" "unprognostic (2.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (9.87e-2)" 106.0 97.1 40.7 92.6 43.5 122.1 136.1 44.2 50.8 155.6 59.5 132.5 123.7 102.5 203.3 111.9 102.3 96.1 116.5 40.5 45.3 102.8 271.1 85.4 72.7 46.6 46.6 101.5 229.1 99.3 65.0 125.4 46.9 140.5 140.7 56.9 227.6 102.2 131.0 74.8 110.5 102.1 46.0 63.2 133.8 58.5 44.2 69.1 197.6 112.1 95.2 118.6 71.4 53.8 237.7 204.9 133.4 232.2 295.7 260.2 317.5 401.2 318.5 246.8 194.2 209.9 198.9 199.3 210.7 398.7 169.4 228.1 181.8 214.5 257.3 155.2 169.3 217.3 114.0 267.6 559.5 296.9 178.1 220.5 349.2 212.6 286.0 352.7 234.7 133.5 223.1 132.9 255.6 175.1 159.8 242.7 192.9 201.0 206.6 164.8 216.8 235.7 303.9 349.1 166.5 143.1 267.3 263.6 273.7 160.0 450.2 237.2 226.2 210.1 132.4 204.9 227.5 292.3 290.7 167.6 248.3 192.9 254.2 249.7 143.2 145.9 157.0 147.5 198.8 111.8 137.0 148.4 158.6 102.5 110.3 129.4 111.1 148.5 141.3 242.5 140.1 142.2 40.7 43.5 44.2 50.8 40.5 45.3 46.6 46.6 46.9 46.0 44.2 53.8 97.1 48.1 71.5 9.1 148.8 417.4 290.3 348.5 207.1 50.1 258.8 98.0 167.2 213.1 233.2 154.5 20.9 281.5 166.9 169.6 117.4 325.1 12.2 89.2 136.5 142.0 170.7 76.3 20.0 249.6 678.6 242.7 156.5 136.8 92.6 88.4 143.5 538.8 215.8 48.8 20.3 352.4 321.4 141.7 414.3 13.9 181.4 128.5 378.8 17.8 129.8 124.1 195.7 19.6 27.5 224.9 158.5 153.4 521.0 486.3 178.1 163.0 142.1 54.7 164.3 112.6 193.5 165.9 150.6 289.8 498.8 451.9 154.3 125.0 263.9 389.2 TMED3 "C15orf22, p24B, p24g4, p24gamma4" ENSG00000166557 "Transmembrane p24 trafficking protein 3" Q9Y3Q3 15 79311112-79427432 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 409.4" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 294.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049314, HPA076949" Enhanced Supported "Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA049314: AB_2680708, HPA076949: AB_2686820" "prognostic unfavorable (7.71e-4)" "unprognostic (1.60e-1)" "unprognostic (3.54e-3)" "unprognostic (8.86e-3)" "unprognostic (1.41e-1)" "unprognostic (2.03e-3)" "unprognostic (2.42e-2)" "unprognostic (2.49e-1)" "unprognostic (4.85e-1)" "unprognostic (9.06e-2)" "unprognostic (8.09e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.16e-1)" "unprognostic (2.88e-1)" "unprognostic (2.50e-1)" "unprognostic (1.52e-1)" 25.9 26.2 19.6 23.1 19.2 37.0 66.4 21.5 20.5 56.6 30.6 49.9 25.4 38.3 138.7 132.3 38.7 37.8 41.9 20.8 31.9 34.7 12.4 30.9 26.0 22.4 22.0 30.9 246.7 54.9 89.6 42.4 26.5 60.0 55.4 11.3 409.4 54.6 4.6 106.8 26.6 37.3 21.6 32.4 73.1 35.0 22.6 23.1 76.3 7.2 37.8 48.7 75.1 25.1 68.1 169.0 31.9 63.6 220.3 167.5 69.0 153.0 206.7 103.3 126.9 141.4 123.3 31.5 117.3 236.0 135.9 124.5 95.7 98.5 53.0 62.7 145.6 104.5 143.0 110.3 131.5 112.2 200.4 126.5 144.4 59.6 86.9 123.5 120.8 105.9 47.1 0.6 101.4 144.3 32.1 106.0 45.7 251.6 92.2 39.1 47.4 158.9 94.2 51.4 99.4 48.8 80.6 162.1 159.3 103.5 141.5 81.7 98.5 85.2 75.7 2.2 111.4 61.7 78.8 44.1 109.8 180.7 103.1 74.9 69.8 95.1 58.1 85.3 62.7 75.5 57.2 63.9 106.7 63.6 71.4 69.1 6.0 61.4 95.7 109.1 73.1 92.2 19.6 19.2 21.5 20.5 20.8 31.9 22.4 22.0 26.5 21.6 22.6 25.1 9.9 28.9 43.6 6.8 41.2 95.8 109.4 125.6 64.9 14.9 153.8 132.8 16.9 55.8 108.5 57.0 8.4 167.8 40.7 67.7 23.5 143.4 48.9 31.6 39.6 31.7 83.9 33.7 10.0 250.5 294.5 68.1 54.6 70.4 47.0 44.0 65.7 6.4 100.5 13.5 10.2 219.3 87.5 52.7 54.4 118.6 49.7 49.2 85.4 9.4 60.0 38.0 44.3 17.1 12.9 173.3 79.9 27.4 71.1 165.2 43.9 28.9 37.7 17.0 19.7 25.6 57.0 51.1 60.3 104.7 121.8 172.4 30.4 64.6 126.4 200.1 TMED4 "HNLF, p24a3, p24alpha3" ENSG00000158604 "Transmembrane p24 trafficking protein 4" Q7Z7H5 7 44577894-44582287 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014650 Approved "Intracellular and membrane" NA NA 24000 "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA014650: AB_1858066" "unprognostic (7.34e-2)" "unprognostic (1.68e-3)" "unprognostic (1.46e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (2.09e-3)" "unprognostic (4.50e-3)" "unprognostic (2.54e-2)" "unprognostic (3.38e-2)" "unprognostic (1.77e-1)" "unprognostic (1.61e-1)" "unprognostic (2.42e-3)" "unprognostic (4.65e-2)" "prognostic favorable (1.37e-4)" "unprognostic (1.21e-1)" "unprognostic (6.12e-2)" "unprognostic (4.11e-1)" "unprognostic (6.61e-2)" 35.2 51.7 40.5 32.2 48.3 49.5 42.9 44.8 43.2 48.9 53.2 46.5 87.9 51.2 78.6 37.3 53.9 37.2 65.0 40.9 48.5 88.3 49.0 42.1 37.1 47.8 45.3 72.0 73.0 139.4 68.3 61.9 47.9 57.5 48.1 92.0 67.3 65.1 61.5 40.5 92.8 44.3 44.1 38.5 51.7 31.4 44.0 38.3 114.0 41.6 38.1 42.3 40.5 56.7 47.2 57.0 80.0 90.8 70.7 41.8 68.6 55.7 68.8 56.4 70.1 62.2 114.1 44.5 90.9 60.0 120.8 74.9 42.5 46.7 67.9 59.3 69.0 39.5 100.4 59.6 63.7 63.8 72.8 54.5 69.7 59.7 48.4 103.8 50.7 68.9 62.8 96.4 67.6 42.4 61.8 86.2 51.5 73.1 57.5 52.6 37.2 87.4 81.7 76.6 64.0 91.3 59.4 132.7 64.4 90.7 103.8 64.1 47.3 41.3 61.0 47.8 88.1 143.9 140.0 53.6 84.6 67.5 148.8 95.3 60.2 87.2 85.3 63.3 103.4 67.4 85.0 82.2 55.1 54.5 69.5 77.8 58.5 82.8 71.3 120.7 79.2 56.6 40.5 48.3 44.8 43.2 40.9 48.5 47.8 45.3 47.9 44.1 44.0 56.7 41.4 118.6 74.0 11.8 70.3 56.2 53.5 61.0 44.9 150.5 83.2 77.2 69.8 62.9 66.0 154.5 75.0 176.0 83.5 79.7 41.1 79.4 54.9 79.3 61.7 36.8 62.9 49.2 25.5 60.6 57.4 75.2 45.9 92.9 41.1 89.9 36.4 55.5 70.7 112.7 30.2 75.0 63.1 45.9 55.0 100.4 78.3 50.4 40.9 12.2 56.9 115.7 41.2 25.1 31.0 79.0 78.6 81.3 142.7 75.6 267.7 140.9 69.4 135.9 59.2 87.1 65.8 51.8 60.8 47.0 56.8 159.9 74.1 60.3 79.6 76.3 TMED5 "CGI-100, p24g2, p24gamma2" ENSG00000117500 "Transmembrane p24 trafficking protein 5" Q9Y3A6 1 93149742-93180516 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050289 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA050289: AB_2681074" "unprognostic (3.35e-1)" "unprognostic (1.44e-2)" "unprognostic (2.02e-3)" "unprognostic (4.38e-1)" "unprognostic (3.16e-1)" "unprognostic (4.86e-2)" "unprognostic (2.83e-3)" "unprognostic (6.37e-2)" "unprognostic (8.60e-2)" "unprognostic (3.72e-2)" "unprognostic (1.64e-2)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "unprognostic (6.01e-2)" "unprognostic (1.86e-1)" "unprognostic (4.46e-2)" "unprognostic (1.38e-1)" 19.1 18.5 5.4 18.8 6.4 31.1 9.2 7.4 6.7 9.6 15.6 15.2 16.7 6.6 12.9 9.2 6.0 15.2 12.5 5.4 8.3 27.7 51.9 18.5 16.0 7.6 6.3 6.8 14.1 11.6 5.4 16.6 7.9 11.1 13.7 4.9 13.5 8.0 19.8 4.8 15.5 8.6 7.5 13.6 14.7 8.1 8.4 10.2 16.2 18.7 13.6 18.3 6.1 9.2 46.5 19.4 21.0 21.4 60.4 36.2 46.5 36.2 35.5 28.4 41.9 33.1 35.5 22.5 36.1 31.2 60.5 24.6 24.3 22.0 32.2 25.7 30.5 21.0 19.9 34.9 36.0 24.8 30.7 43.0 31.9 44.3 40.3 32.5 34.4 18.1 35.6 62.3 28.0 7.5 27.4 19.4 13.9 25.1 26.1 20.6 35.8 36.5 36.2 25.9 12.3 14.1 43.6 39.4 41.0 17.4 18.6 20.9 34.4 30.1 29.6 38.4 37.6 42.5 57.8 27.4 20.1 23.3 13.6 56.7 32.4 45.4 22.0 32.6 26.4 24.2 22.5 25.9 26.6 17.9 16.9 20.0 15.8 16.2 36.0 18.2 27.7 28.9 5.4 6.4 7.4 6.7 5.4 8.3 7.6 6.3 7.9 7.5 8.4 9.2 39.0 73.7 45.9 21.2 66.6 71.8 81.7 39.3 55.2 5.8 33.2 22.9 42.3 34.3 37.7 58.8 20.9 36.1 61.1 52.5 11.7 34.3 97.8 32.5 33.2 33.1 20.4 20.4 16.6 40.8 87.3 59.4 50.4 52.3 40.5 18.9 18.9 116.1 68.1 8.4 19.2 32.9 26.4 74.9 91.7 143.6 23.6 78.6 33.8 22.5 57.9 13.2 46.4 32.2 42.0 37.2 48.8 16.1 163.4 101.9 53.6 66.2 29.2 8.5 59.2 52.1 49.1 32.1 15.0 53.7 64.8 85.4 64.5 19.7 35.5 115.8 TMED7 "CGI-109, FLJ90481, p24g3, p24gamma3" ENSG00000134970 "Transmembrane p24 trafficking protein 7" Q9Y3B3 5 115613210-115632992 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008960, CAB025883" Supported NA NA 13000 "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB025883: , HPA008960: AB_1080280" "unprognostic (1.40e-1)" "unprognostic (8.42e-2)" "unprognostic (1.45e-2)" "unprognostic (1.22e-1)" "unprognostic (2.04e-1)" "unprognostic (4.35e-2)" "unprognostic (1.27e-1)" "unprognostic (2.26e-3)" "unprognostic (2.02e-1)" "unprognostic (2.11e-2)" "unprognostic (6.15e-3)" "unprognostic (4.10e-2)" "unprognostic (6.82e-2)" "unprognostic (4.95e-2)" "unprognostic (3.06e-1)" "unprognostic (4.79e-2)" "unprognostic (1.22e-1)" 35.0 41.2 23.1 29.5 31.9 31.8 37.8 31.2 32.7 50.5 37.8 42.1 36.9 41.2 70.2 32.4 38.6 33.5 43.5 21.9 24.6 54.2 80.2 30.5 23.4 39.8 27.2 31.0 35.2 53.6 28.0 43.8 28.1 48.7 42.3 19.2 43.4 44.3 22.0 18.9 38.3 45.0 33.3 25.9 41.5 18.9 28.5 19.5 79.8 24.9 24.1 37.6 22.6 44.8 63.6 42.4 43.8 54.7 112.3 84.4 68.1 109.8 116.4 79.7 129.8 36.3 110.1 33.1 105.7 115.1 99.5 49.6 41.3 128.0 125.7 76.0 34.4 30.5 39.2 76.8 119.8 31.9 59.0 78.2 60.5 76.1 95.8 100.4 78.5 22.3 29.6 44.5 87.1 30.1 24.0 28.5 30.8 37.7 35.5 25.9 65.1 63.8 98.6 44.6 33.3 39.8 90.0 52.3 68.1 41.7 63.0 41.8 80.1 109.0 46.3 79.2 66.3 29.3 24.0 33.5 88.7 52.2 61.8 25.5 23.8 20.2 14.9 23.1 15.3 10.4 11.5 13.3 19.3 9.1 11.1 12.0 16.3 14.2 18.5 13.3 11.5 20.7 23.1 31.9 31.2 32.7 21.9 24.6 39.8 27.2 28.1 33.3 28.5 44.8 37.8 38.5 29.8 0.0 26.9 45.6 30.1 35.3 15.4 31.5 47.4 21.5 42.4 61.5 29.3 46.0 10.4 44.2 30.6 63.8 13.7 37.4 28.7 34.5 48.9 30.6 87.3 9.1 0.0 28.3 103.6 51.8 34.1 45.6 10.1 20.4 44.3 114.2 50.1 30.3 0.0 85.8 24.4 51.6 55.5 20.1 46.9 38.4 51.6 0.0 36.8 52.6 19.6 0.0 0.0 37.4 39.9 53.4 13.9 60.5 50.0 42.2 36.9 25.8 39.5 42.9 43.1 39.2 18.0 25.3 44.0 82.8 23.6 33.9 46.9 55.6 TMED7-TICAM2 ENSG00000251201 "TMED7-TICAM2 readthrough" 5 115578642-115626161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Astrocytes: 2.9;Excitatory neurons: 4.8;Inhibitory neurons: 5.1;Microglial cells: 4.7;Oligodendrocyte precursor cells: 5.5;Oligodendrocytes: 13.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA008960 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008960: AB_1080280" "unprognostic (7.37e-6)" "unprognostic (5.18e-4)" "unprognostic (2.84e-2)" "unprognostic (8.53e-2)" "unprognostic (5.16e-2)" "unprognostic (5.79e-3)" "unprognostic (1.47e-3)" "unprognostic (6.56e-5)" "unprognostic (1.03e-1)" "unprognostic (8.25e-2)" "unprognostic (3.91e-3)" "unprognostic (1.20e-1)" "unprognostic (8.61e-5)" "unprognostic (1.25e-1)" "unprognostic (5.19e-2)" "unprognostic (2.32e-2)" "unprognostic (6.42e-2)" 1.9 2.6 1.2 2.9 1.3 1.0 1.6 1.5 2.6 3.2 0.7 1.9 1.8 1.7 1.8 1.2 1.6 1.7 0.8 1.0 1.3 2.1 2.5 2.0 1.8 1.7 1.5 1.3 1.5 1.7 0.4 4.1 1.7 2.0 1.9 2.8 1.3 3.0 0.4 0.4 2.0 2.6 1.6 2.6 2.3 0.9 1.5 1.9 2.0 1.0 2.7 2.6 0.4 2.0 4.1 2.9 2.7 10.9 16.2 30.7 10.2 19.0 14.9 11.2 19.9 2.5 9.6 1.1 8.4 21.4 7.7 8.1 1.8 11.4 22.1 9.4 2.1 0.7 1.5 0.3 12.1 2.2 5.5 15.1 9.9 12.5 12.8 19.6 7.0 1.6 1.4 3.3 13.7 4.6 1.7 0.5 0.4 9.6 4.4 1.4 4.6 1.3 9.2 2.2 2.1 3.1 8.8 0.9 15.6 11.1 1.5 3.1 11.8 10.4 11.3 9.8 16.8 5.7 4.5 1.2 11.1 3.1 8.2 1.8 3.4 1.3 0.5 3.9 1.1 0.4 0.4 0.6 3.4 0.3 0.4 0.4 1.1 0.6 3.1 0.5 0.8 1.3 1.2 1.3 1.5 2.6 1.0 1.3 1.7 1.5 1.7 1.6 1.5 2.0 0.0 3.2 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 4.8 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 5.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 4.7 1.1 0.0 0.0 5.5 13.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.2 TMEM101 "FLJ23987, MGC4251" ENSG00000091947 "Transmembrane protein 101" Q96IK0 17 44011188-44023946 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Endometrial ciliated cells: 237.2;Glandular and luminal cells: 507.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039739, HPA075651" Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 1: Thyroid gland - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Plasma membrane" "HPA039739: AB_2676657, HPA075651: " "unprognostic (1.40e-3)" "unprognostic (1.75e-1)" "unprognostic (1.67e-1)" "prognostic favorable (4.29e-4)" "unprognostic (5.91e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.80e-2)" "unprognostic (2.43e-1)" "unprognostic (2.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "prognostic favorable (4.10e-5)" "unprognostic (1.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" 17.2 19.8 22.6 12.9 26.8 11.5 107.0 23.2 24.0 44.4 24.2 20.6 16.9 63.5 27.6 28.0 37.9 15.9 23.1 22.2 22.7 93.9 24.1 18.7 19.4 24.2 24.0 22.7 39.2 26.4 15.4 21.6 23.2 24.0 16.9 12.1 30.1 111.8 33.3 29.0 17.4 16.1 23.5 20.4 28.8 23.6 23.9 16.5 23.0 24.9 17.7 20.4 23.0 23.4 23.5 56.0 19.7 16.2 45.7 43.9 19.6 24.1 36.1 46.5 43.8 42.0 59.5 26.1 6.5 24.9 36.0 35.3 22.9 41.5 35.2 28.5 46.1 19.5 45.7 86.2 39.3 31.7 32.8 39.4 46.5 32.8 46.3 41.8 40.8 45.0 40.7 50.1 29.2 31.7 34.6 36.6 9.1 25.4 62.6 29.8 42.8 47.4 39.1 18.7 25.3 20.2 14.6 0.5 59.6 24.9 27.3 59.9 24.7 42.1 28.5 18.8 46.9 52.1 38.0 12.0 44.3 29.7 38.2 20.1 42.8 15.3 31.2 43.4 35.7 37.3 39.6 36.4 44.9 39.8 43.2 35.7 15.9 44.1 32.9 44.0 44.6 31.1 22.6 26.8 23.2 24.0 22.2 22.7 24.2 24.0 23.2 23.5 23.9 23.4 22.1 19.2 15.4 0.0 22.8 20.6 31.6 72.0 21.6 10.4 64.2 61.2 27.3 24.3 34.5 40.5 6.2 68.5 19.6 18.5 37.2 36.6 13.1 237.2 70.8 28.2 23.4 33.2 0.0 49.8 47.3 21.1 13.7 507.4 22.9 34.4 36.0 20.6 37.6 11.8 0.0 37.3 28.5 32.4 11.8 11.1 13.1 23.8 33.8 0.0 47.7 17.7 29.9 0.0 0.0 41.8 20.7 12.4 29.4 23.4 27.7 30.2 27.1 11.7 6.6 13.2 19.8 45.8 24.7 26.9 22.6 44.6 20.9 25.6 45.7 25.2 TMEM107 "JBTS29, MGC10744, MKS13" ENSG00000179029 "Transmembrane protein 107" Q6UX40 17 8172457-8176399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 110.8;Respiratory ciliated cells: 164.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052555, HPA059653" Approved Approved "Nucleoplasm,Plasma membrane,Midbody ring" Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Plasma membrane" "Midbody ring" "HPA052555: AB_2681870, HPA059653: AB_2684096" "unprognostic (2.87e-2)" "unprognostic (2.67e-1)" "unprognostic (2.85e-2)" "prognostic favorable (9.39e-5)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (5.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (6.02e-3)" "unprognostic (1.83e-2)" "unprognostic (1.87e-1)" "unprognostic (2.66e-3)" "unprognostic (1.26e-1)" "unprognostic (4.99e-1)" "unprognostic (2.66e-1)" "unprognostic (1.49e-1)" 9.6 13.4 11.1 6.6 12.0 15.0 9.8 12.2 13.3 10.6 19.3 9.0 3.5 11.3 20.7 10.5 27.0 7.2 9.2 11.9 12.8 14.7 4.4 11.3 7.4 13.0 12.6 7.8 11.2 16.9 23.5 6.8 12.2 7.3 5.0 29.6 10.7 6.5 1.6 12.0 7.6 6.6 12.1 13.7 8.0 17.1 12.3 8.9 16.1 1.8 7.6 8.4 9.6 12.5 45.0 16.9 21.8 11.3 12.2 17.8 4.8 11.1 8.2 8.2 10.9 2.0 26.6 10.5 14.6 9.7 7.4 30.5 8.3 16.9 13.6 18.1 11.5 7.6 29.0 4.7 4.9 2.6 8.3 7.9 11.2 20.7 9.4 18.4 13.1 17.7 5.9 23.5 18.0 12.2 6.8 7.7 2.2 6.3 7.2 13.1 6.5 19.1 15.8 3.5 7.3 10.7 13.5 2.4 9.1 5.1 8.1 8.8 10.6 4.8 9.6 7.6 6.1 9.5 5.5 4.9 27.3 10.0 8.7 21.0 22.1 51.6 28.2 27.9 24.3 45.4 27.6 30.3 19.7 59.2 30.9 32.2 20.0 26.4 56.8 31.6 24.8 21.0 11.1 12.0 12.2 13.3 11.9 12.8 13.0 12.6 12.2 12.1 12.3 12.5 30.8 9.6 9.8 2.9 38.1 19.2 19.5 35.2 11.4 17.3 31.1 43.3 7.9 35.8 25.1 33.1 45.9 17.3 30.0 12.9 13.7 21.7 12.2 99.9 22.9 25.1 9.1 15.4 5.1 11.1 21.3 18.2 48.9 26.9 36.7 12.7 27.1 24.0 45.5 11.8 3.6 14.1 16.2 45.6 31.6 10.1 12.8 55.9 33.8 3.7 22.0 37.7 28.8 1.5 1.7 11.0 12.7 15.1 110.8 16.3 26.0 21.7 164.3 63.2 0.0 15.3 16.8 69.4 50.3 13.0 28.6 13.3 34.8 13.2 17.6 11.1 TMEM108 "CT124, MGC3040" ENSG00000144868 "Transmembrane protein 108" Q6UXF1 3 133038391-133397775 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.2;skeletal muscle: 23.1" "Cell type enhanced" "Detected in many" "Astrocytes: 209.9;Excitatory neurons: 357.3;Inhibitory neurons: 475.3;Oligodendrocyte precursor cells: 480.0" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 24.2;LHCN-M2: 13.8;SCLC-21H: 21.0;SH-SY5Y: 92.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063350 Enhanced Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 55000 "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoli, Vesicles" "HPA063350: AB_2684993" "unprognostic (4.75e-2)" "unprognostic (1.73e-2)" "unprognostic (9.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.07e-3)" "unprognostic (3.17e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-2)" "unprognostic (2.06e-4)" "unprognostic (2.08e-1)" "unprognostic (7.27e-4)" "unprognostic (1.11e-1)" "unprognostic (3.03e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-2)" "unprognostic (6.12e-2)" "unprognostic (1.36e-2)" 1.4 11.3 6.3 1.5 9.6 0.2 1.5 3.4 10.0 2.0 3.2 1.5 0.4 2.4 0.6 9.6 1.7 0.8 6.8 9.6 2.9 0.4 0.1 11.0 1.7 0.0 4.1 0.3 0.3 3.0 2.2 2.4 4.0 1.0 1.3 35.2 1.3 2.0 23.1 1.4 1.6 5.5 0.0 1.3 1.3 13.9 7.9 1.3 3.1 7.0 2.3 8.3 0.8 0.8 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.1 1.0 0.0 0.0 0.1 0.2 0.0 0.7 1.0 1.8 8.5 0.0 0.0 0.0 0.0 24.2 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 13.8 0.7 0.1 0.3 3.8 0.0 0.0 0.0 4.8 0.1 1.1 0.0 21.0 92.6 0.0 0.1 0.3 5.5 0.2 0.0 0.0 0.1 0.1 0.0 3.4 1.3 0.0 0.7 1.8 0.0 3.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 9.6 3.4 10.0 9.6 2.9 0.0 4.1 4.0 0.0 7.9 0.8 0.6 3.2 4.6 209.9 0.0 2.4 0.5 0.2 0.0 10.4 1.3 2.8 1.7 1.5 5.0 0.0 102.2 1.8 0.0 0.0 0.0 0.0 80.6 1.0 0.6 1.3 0.0 0.0 357.3 0.4 8.6 4.6 4.1 0.2 1.3 5.5 0.4 0.0 0.3 1.7 475.3 0.0 0.0 0.0 0.8 38.2 0.9 0.1 0.0 33.7 0.0 5.7 0.0 480.0 22.2 0.3 0.0 0.7 1.2 0.2 0.0 0.0 0.0 57.6 0.0 6.8 3.3 17.2 11.2 0.0 1.6 1.1 1.0 4.9 0.0 0.4 TMEM116 FLJ90167 ENSG00000198270 "Transmembrane protein 116" Q8NCL8 12 111931282-112013185 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "parathyroid gland: 59.7" "Cell type enhanced" "Detected in many" "Early spermatids: 67.8;Spermatocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in all" 4 "T-cells: 19.3" "Cell line enhanced" "Detected in many" "RT4: 33.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040720 Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Microtubules Nucleoplasm "HPA040720: AB_10795623" "unprognostic (8.91e-2)" "unprognostic (1.95e-3)" "unprognostic (1.18e-2)" "unprognostic (1.71e-1)" "unprognostic (5.48e-2)" "unprognostic (3.25e-1)" "unprognostic (2.93e-2)" "unprognostic (6.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.34e-1)" "unprognostic (3.27e-3)" "unprognostic (9.12e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.41e-1)" "unprognostic (1.33e-1)" "unprognostic (2.85e-2)" "unprognostic (3.19e-3)" 3.8 8.8 7.0 2.2 7.8 1.2 11.4 9.2 8.4 6.0 27.5 4.2 11.1 2.7 7.1 4.2 4.9 6.8 26.3 6.4 6.5 30.8 12.3 8.5 4.5 7.2 7.5 5.2 4.2 59.7 6.5 2.9 7.2 3.9 3.7 7.0 13.3 5.9 6.6 11.1 6.3 2.1 6.9 3.4 10.2 27.1 7.5 5.4 6.3 5.8 6.8 7.4 3.2 8.5 6.2 6.4 8.9 9.7 8.3 6.6 6.0 5.1 7.5 6.1 6.6 4.6 5.1 6.9 2.9 3.5 7.6 5.9 4.8 5.1 5.4 17.1 4.1 4.4 5.4 5.1 13.2 1.6 0.7 7.8 8.5 7.7 13.5 6.7 2.2 13.2 8.7 5.0 6.5 9.4 2.3 14.2 10.6 14.5 3.9 7.0 3.8 12.2 18.9 33.1 8.1 5.6 5.3 4.4 8.3 11.7 16.0 22.9 1.6 5.8 1.8 5.1 2.2 6.5 12.1 6.6 7.9 5.5 8.0 1.1 2.6 4.5 8.1 4.5 6.8 2.9 18.5 15.6 2.9 3.6 9.6 10.8 0.4 2.4 3.5 4.2 19.3 4.0 7.0 7.8 9.2 8.4 6.4 6.5 7.2 7.5 7.2 6.9 7.5 8.5 4.0 3.2 18.5 17.3 6.2 5.5 6.2 8.8 7.4 11.2 14.0 12.8 21.7 7.2 10.1 29.5 16.7 18.6 10.2 5.7 23.5 4.2 67.8 7.0 4.3 3.5 0.0 3.4 28.3 4.0 5.9 5.9 7.7 3.7 5.7 7.0 2.2 5.4 5.1 10.1 25.6 4.6 24.4 4.1 4.5 33.5 9.3 3.9 7.2 7.5 3.6 13.4 11.3 13.0 33.3 2.7 3.2 4.9 5.5 4.2 20.9 10.3 18.6 17.3 6.6 6.5 6.6 123.5 37.4 6.2 5.4 40.1 17.4 7.0 6.0 7.6 TMEM119 OBIF ENSG00000183160 "Transmembrane protein 119" Q4V9L6 12 108589851-108598320 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biomineralization, Differentiation, Osteogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 8.3;Fibroblasts: 30.5;Late spermatids: 9.3;Melanocytes: 8.8;Microglial cells: 15.0;Peritubular cells: 24.0;Smooth muscle cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 559.2;ASC TERT1: 152.6;BJ hTERT+: 168.0;fHDF/TERT166: 81.9;HSkMC: 238.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051870, HPA052650" Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA051870: AB_2681645, HPA052650: AB_2681901" "unprognostic (4.90e-2)" "unprognostic (2.66e-1)" "unprognostic (6.84e-2)" "unprognostic (5.97e-2)" "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (6.67e-2)" "unprognostic (8.40e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.61e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.29e-2)" "unprognostic (8.76e-3)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" 29.6 8.0 7.6 16.2 8.9 3.0 27.1 8.5 9.2 61.0 5.3 12.6 15.1 18.9 14.1 6.9 11.9 35.8 9.4 7.7 9.3 6.0 0.9 37.6 47.8 17.2 12.1 1.4 7.5 5.6 6.1 6.6 14.9 12.7 15.1 0.9 6.8 26.0 1.6 13.9 23.1 11.2 13.4 11.4 10.5 5.9 16.4 5.1 21.7 1.7 27.2 32.2 18.4 21.9 0.1 0.3 1.3 0.7 559.2 152.6 0.8 11.8 168.0 0.4 3.0 0.2 0.6 0.3 0.4 81.9 0.3 0.2 0.1 0.2 0.1 0.5 0.0 0.3 0.6 1.0 7.2 0.3 1.2 238.4 0.3 7.0 0.1 0.7 0.1 0.2 0.5 0.5 0.5 0.7 0.3 1.6 0.1 0.0 0.9 0.6 0.9 0.8 0.1 0.7 0.2 39.5 0.0 0.3 0.3 4.5 0.2 1.8 1.2 13.1 0.4 11.2 0.5 2.6 3.1 0.6 6.8 0.5 0.1 1.4 0.2 0.3 0.2 0.1 0.2 0.2 0.4 0.2 0.1 0.4 0.3 0.3 1.4 0.2 0.4 0.2 0.1 0.1 7.6 8.9 8.5 9.2 7.7 9.3 17.2 12.1 14.9 13.4 16.4 21.9 1.3 0.0 0.0 0.0 0.2 3.8 0.1 0.0 0.6 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 8.3 0.2 5.8 1.3 0.0 0.0 0.0 0.0 0.2 30.5 0.0 0.2 0.0 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 1.9 4.4 9.3 4.1 1.1 8.8 15.0 1.6 0.0 0.0 0.0 0.0 0.1 1.1 24.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 9.7 0.1 0.1 0.0 3.7 0.3 0.7 0.5 0.0 0.1 TMEM143 FLJ10922 ENSG00000161558 "Transmembrane protein 143" Q96AN5 19 48332356-48364059 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 43.6;skeletal muscle: 95.5;tongue: 61.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014476, HPA058645" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli fibrillar center" "HPA014476: AB_1858092, HPA058645: " "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (5.23e-2)" "unprognostic (2.50e-1)" "unprognostic (5.94e-2)" "unprognostic (2.11e-3)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (4.08e-1)" "unprognostic (2.25e-1)" "unprognostic (7.29e-2)" "unprognostic (9.82e-2)" "prognostic favorable (1.53e-7)" "unprognostic (5.46e-2)" "unprognostic (1.24e-1)" "unprognostic (6.75e-2)" "unprognostic (1.04e-1)" 6.5 9.0 5.2 2.6 6.0 2.7 5.2 5.3 6.8 4.9 4.3 7.2 4.5 4.3 2.5 4.6 4.5 3.2 43.6 5.2 5.4 10.4 18.1 4.3 3.7 5.5 5.5 4.7 5.7 3.7 5.1 2.7 5.5 5.3 2.7 3.3 5.6 2.6 95.5 5.8 6.8 2.2 4.7 7.7 6.8 4.2 5.7 6.2 6.4 61.2 2.3 6.2 4.3 5.9 4.6 7.4 2.3 4.2 4.5 6.3 4.7 4.2 2.5 2.9 3.7 6.3 5.9 8.6 7.5 2.8 1.4 5.2 2.3 3.0 1.6 10.6 5.2 5.2 6.3 10.1 3.6 4.1 4.8 5.8 3.7 1.5 3.7 3.3 2.4 12.9 3.8 12.5 3.1 2.6 5.9 14.8 2.9 8.7 2.5 8.6 1.4 14.2 3.9 3.4 8.6 8.5 2.5 3.1 2.1 2.6 4.4 2.9 2.9 3.5 3.9 2.6 1.6 24.3 8.2 6.5 2.9 5.4 2.8 1.9 1.2 1.4 2.2 0.7 2.7 2.1 1.7 2.1 1.5 1.5 2.6 1.5 1.0 3.4 1.2 0.6 1.3 1.3 5.2 6.0 5.3 6.8 5.2 5.4 5.5 5.5 5.5 4.7 5.7 5.9 2.3 3.2 1.1 8.1 3.7 0.3 3.0 3.4 2.8 3.3 3.2 1.8 27.0 0.0 2.0 1.8 8.4 9.5 2.8 3.7 13.7 3.5 0.7 2.0 1.4 2.2 3.0 4.8 9.8 2.4 6.1 3.3 5.6 1.3 1.3 4.6 1.4 7.5 5.5 0.0 8.7 4.4 4.1 2.1 1.0 1.3 2.5 2.6 8.8 6.5 2.5 3.9 2.1 5.5 9.9 1.2 7.1 1.2 7.6 0.9 8.5 14.6 5.3 6.7 0.0 2.5 3.1 8.7 5.5 3.1 1.0 3.7 3.6 3.4 4.3 1.2 TMEM150A "FLJ90024, TM6P1, TMEM150, TTN1" ENSG00000168890 "Transmembrane protein 150A" Q86TG1 2 85598547-85603196 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 133.5;Early spermatids: 137.5;Proximal tubular cells: 85.0;Syncytiotrophoblasts: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 52.9;HHSteC: 49.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019015 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA019015: AB_2204758" "unprognostic (2.80e-1)" "unprognostic (1.62e-2)" "unprognostic (2.29e-2)" "unprognostic (1.42e-3)" "unprognostic (4.09e-3)" "unprognostic (5.65e-2)" "unprognostic (2.38e-2)" "unprognostic (1.42e-2)" "unprognostic (5.80e-2)" "unprognostic (2.64e-2)" "unprognostic (2.54e-3)" "unprognostic (7.16e-2)" "unprognostic (8.27e-3)" "unprognostic (2.09e-2)" "unprognostic (2.89e-1)" "unprognostic (1.37e-2)" "unprognostic (6.87e-3)" 18.7 16.3 10.0 5.2 10.8 1.2 17.0 9.8 11.1 16.3 11.1 21.0 6.5 17.7 6.3 11.0 17.1 10.4 15.5 9.7 10.3 32.8 38.5 19.3 6.0 11.9 10.7 17.1 37.9 8.0 11.7 22.4 10.9 17.4 4.1 1.4 14.9 10.2 53.7 9.3 12.9 11.5 10.6 9.7 20.6 24.4 11.3 2.5 14.9 27.2 4.2 22.2 13.1 10.1 2.7 5.1 6.3 9.3 52.9 23.7 15.3 5.2 9.1 4.3 2.0 23.6 7.1 0.8 19.8 15.3 8.0 2.2 6.8 13.7 2.0 1.2 6.7 1.5 3.0 39.9 49.6 0.4 4.7 28.5 18.4 7.0 9.9 20.6 15.2 1.0 14.0 1.5 17.5 11.9 0.4 6.9 11.5 10.8 5.1 4.1 0.6 15.8 13.4 10.6 1.0 3.9 5.4 35.4 13.5 5.9 8.7 6.2 12.6 5.2 4.4 4.5 1.8 10.6 2.8 5.2 8.5 6.0 2.3 0.0 15.2 7.2 5.5 17.9 6.5 5.3 6.2 5.6 12.8 8.1 6.9 4.2 0.7 8.4 15.1 7.6 1.5 6.0 10.0 10.8 9.8 11.1 9.7 10.3 11.9 10.7 10.9 10.6 11.3 10.1 24.1 9.6 14.9 10.7 9.0 4.5 15.3 16.0 10.2 6.8 15.3 12.7 5.2 12.8 16.2 14.7 0.0 133.5 10.4 3.5 29.4 16.9 137.5 5.0 9.0 14.9 3.0 1.7 3.9 14.4 18.2 14.3 5.6 6.0 10.2 5.2 15.7 19.7 37.9 3.3 5.0 5.2 16.2 10.3 13.1 64.8 19.9 14.6 10.6 9.4 15.2 6.5 7.2 5.5 5.9 12.8 7.0 24.5 5.9 20.3 16.4 85.0 8.3 3.4 13.1 14.6 11.7 2.4 5.6 7.9 3.7 146.0 7.0 9.2 7.0 13.1 TMEM168 DKFZp564C012,FLJ13576 ENSG00000146802 "Transmembrane protein 168" Q9H0V1 7 112762377-112790423 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020389, HPA077143" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Cytosol "HPA020389: AB_1858101, HPA077143: " "unprognostic (1.54e-1)" "unprognostic (2.23e-1)" "unprognostic (2.55e-1)" "unprognostic (4.92e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-2)" "unprognostic (2.30e-3)" "prognostic favorable (4.07e-6)" "unprognostic (1.60e-3)" "unprognostic (8.73e-2)" "unprognostic (3.07e-3)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (2.47e-1)" "unprognostic (1.84e-1)" "unprognostic (4.89e-3)" "unprognostic (3.30e-2)" 12.9 10.6 6.0 12.5 7.6 6.7 15.6 7.5 7.1 11.6 9.5 22.4 13.7 13.2 17.9 14.1 10.7 12.2 13.9 5.8 6.8 12.8 8.4 12.1 11.3 8.1 6.6 12.1 6.7 28.6 8.3 14.4 8.2 16.3 24.6 20.2 20.6 13.4 9.4 26.7 14.8 15.3 7.8 12.3 12.6 10.2 6.7 13.5 17.7 9.4 11.2 10.9 12.9 10.1 16.0 13.2 12.2 10.9 20.4 41.5 17.2 17.3 16.2 6.4 5.6 17.0 16.4 16.9 11.4 17.2 14.6 16.8 12.5 15.1 16.5 26.8 12.9 14.7 16.8 9.7 13.7 16.4 17.9 20.3 38.6 7.3 10.9 6.0 18.9 13.6 19.9 15.0 23.3 25.2 14.2 10.3 9.9 16.7 10.2 9.5 6.1 24.9 16.0 29.9 9.2 18.2 23.3 30.6 14.0 14.9 17.5 14.4 27.0 30.5 15.5 14.5 22.6 25.4 23.1 18.9 19.7 14.7 40.0 21.2 14.9 11.6 12.1 12.6 14.4 10.9 12.9 11.8 16.0 13.2 18.6 13.0 8.4 13.5 13.2 11.1 13.0 9.5 6.0 7.6 7.5 7.1 5.8 6.8 8.1 6.6 8.2 7.8 6.7 10.1 17.4 12.8 22.3 43.1 18.6 31.1 19.1 12.0 27.3 31.5 16.4 14.4 18.1 10.0 18.9 33.1 27.1 35.5 14.3 16.9 0.0 5.9 2.9 9.2 22.1 17.3 20.5 14.1 29.9 9.1 8.9 17.6 18.3 11.8 12.0 19.2 18.5 12.6 8.9 16.8 32.6 34.8 16.2 13.5 9.3 1.9 18.3 10.9 24.9 41.2 10.8 16.3 15.5 70.9 71.5 6.1 17.0 14.7 10.2 21.6 15.5 6.0 7.1 29.6 6.6 19.4 16.7 18.1 13.3 24.8 26.0 14.2 13.8 21.1 30.5 14.5 TMEM178A "MGC33926, TMEM178" ENSG00000152154 "Transmembrane protein 178A" Q8NBL3 2 39664982-39717963 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 135.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 32.4;Excitatory neurons: 109.1;Inhibitory neurons: 109.2;Oligodendrocyte precursor cells: 33.7" "Group enriched" "Detected in many" 4 "endometrial cancer: 10.2;glioma: 13.2;prostate cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 138.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052128 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Intestine - Brush border" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA052128: AB_2681738" "unprognostic (3.35e-2)" "unprognostic (3.18e-1)" "unprognostic (5.94e-2)" "unprognostic (2.86e-1)" "unprognostic (1.04e-1)" "unprognostic (5.85e-2)" "unprognostic (3.24e-3)" "unprognostic (1.82e-3)" "unprognostic (2.22e-1)" "unprognostic (9.74e-2)" "unprognostic (5.11e-4)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.80e-3)" "unprognostic (3.46e-2)" "unprognostic (2.83e-2)" "unprognostic (3.01e-3)" 5.9 7.6 65.4 0.6 71.3 0.2 6.2 135.5 104.1 4.1 38.6 8.9 1.9 3.6 1.5 1.8 6.3 2.7 4.5 71.7 51.3 42.7 9.9 6.7 0.5 64.7 54.9 5.9 4.6 2.3 12.9 3.2 65.5 11.6 1.7 15.7 21.9 1.6 2.8 3.3 3.2 2.4 65.7 2.6 8.6 2.2 51.5 0.5 12.3 1.9 0.5 3.9 3.0 108.0 0.0 0.0 138.7 0.1 0.1 3.3 0.2 0.6 0.1 0.0 0.3 0.0 0.3 0.0 3.7 0.0 0.0 0.3 4.5 0.0 0.5 0.3 0.1 0.0 0.0 0.4 1.1 0.1 0.0 2.6 0.3 0.0 0.4 4.3 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.2 17.7 0.2 0.1 1.7 0.0 0.0 1.0 0.2 25.7 0.6 0.0 0.6 0.3 23.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.4 71.3 135.5 104.1 71.7 51.3 64.7 54.9 65.5 65.7 51.5 108.0 3.2 0.0 2.0 14.7 0.0 0.4 0.5 0.6 1.8 9.1 1.1 32.4 3.9 0.0 1.3 12.9 6.2 0.3 0.1 0.8 0.0 0.2 0.4 3.0 1.2 4.3 16.1 0.0 109.1 0.2 0.0 2.6 0.0 6.5 0.0 1.4 0.7 0.5 0.2 1.7 109.2 0.4 2.0 0.0 0.4 0.1 0.0 0.2 1.8 7.5 0.0 1.1 0.0 33.7 19.3 0.4 0.3 0.0 0.0 3.7 0.5 0.7 4.3 6.1 0.0 0.9 0.6 0.2 0.5 0.1 0.6 0.5 0.1 0.5 0.4 0.3 TMEM179 "C14orf90, FLJ42486, TMEM179A" ENSG00000258986 "Transmembrane protein 179" Q6ZVK1 14 104474678-104605647 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 31.5;pituitary gland: 88.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 58.1;Horizontal cells: 65.6" "Group enriched" "Detected in some" 4 "glioma: 2.7;pancreatic cancer: 3.1;testis cancer: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 8.8;SCLC-21H: 37.3;SH-SY5Y: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002942 Uncertain Mitochondria NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA002942: AB_1078113" "unprognostic (8.65e-2)" "unprognostic (8.24e-2)" "unprognostic (3.10e-2)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (1.08e-2)" "unprognostic (3.46e-2)" "unprognostic (2.69e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (2.82e-3)" "unprognostic (1.09e-1)" "unprognostic (1.89e-4)" "unprognostic (8.68e-3)" "unprognostic (1.56e-1)" "unprognostic (9.71e-6)" "unprognostic (1.70e-2)" 0.2 11.4 18.9 0.3 19.3 0.0 0.1 12.0 29.7 0.1 4.6 3.8 0.2 0.1 0.4 0.1 0.3 0.1 1.0 17.8 24.6 0.5 0.5 0.1 0.0 25.9 24.9 0.1 4.0 0.1 88.1 0.8 31.5 0.8 0.2 6.2 0.1 0.1 0.1 0.0 1.4 0.3 12.5 0.0 1.3 5.2 18.8 0.0 0.1 0.0 0.0 0.1 0.7 20.5 0.0 0.5 0.3 0.8 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 37.3 11.6 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 19.3 12.0 29.7 17.8 24.6 25.9 24.9 31.5 12.5 18.8 20.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.0 1.2 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 12.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 65.6 12.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 1.5 0.0 7.5 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.1 0.7 3.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TMEM182 FLJ30294 ENSG00000170417 "Transmembrane protein 182" Q6ZP80 2 102736905-103019900 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 24 "heart muscle: 97.6;skeletal muscle: 150.7;tongue: 127.7" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 150.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA045861 Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Vesicles" "HPA045861: AB_2679475" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (5.10e-2)" "unprognostic (1.12e-4)" "unprognostic (5.35e-2)" "unprognostic (7.01e-2)" "unprognostic (1.13e-2)" "unprognostic (1.10e-1)" "unprognostic (7.03e-3)" "unprognostic (2.34e-1)" "unprognostic (4.19e-2)" "unprognostic (3.42e-2)" "unprognostic (9.88e-2)" "unprognostic (4.61e-2)" "unprognostic (1.10e-1)" "unprognostic (3.53e-1)" "unprognostic (2.36e-2)" 2.7 1.6 2.2 0.7 2.0 0.6 2.3 2.6 2.9 2.9 2.2 1.8 1.9 1.1 5.3 3.9 2.1 1.8 97.6 2.5 3.1 2.1 2.0 1.3 1.8 2.8 2.7 1.5 2.1 3.6 2.6 1.4 3.0 4.0 2.3 1.5 2.0 2.1 150.7 0.5 1.2 1.1 2.5 1.6 2.2 1.4 2.6 1.8 3.0 127.7 1.4 2.2 0.6 2.7 4.9 3.3 2.4 7.3 2.8 2.4 6.9 2.5 2.2 2.4 4.4 10.7 7.3 4.5 9.0 1.4 6.1 3.3 2.6 3.7 5.4 11.6 3.5 6.6 1.4 6.7 3.0 6.2 4.4 3.2 7.6 4.5 5.2 1.9 0.4 6.4 5.2 1.2 3.5 4.6 3.9 5.7 4.2 5.9 3.6 3.4 6.3 3.7 5.7 6.2 5.2 1.9 4.1 3.3 10.3 3.5 3.0 3.2 0.7 4.2 3.5 2.7 3.1 3.9 13.0 5.5 3.8 8.4 6.3 0.0 0.0 0.2 2.5 0.2 2.8 3.6 1.5 1.3 0.9 1.2 2.4 2.4 0.0 2.4 0.3 2.9 0.5 1.1 2.2 2.0 2.6 2.9 2.5 3.1 2.8 2.7 3.0 2.5 2.6 2.7 0.6 22.4 12.3 1.3 3.6 0.4 1.0 1.8 1.2 0.3 8.1 2.4 150.6 0.0 15.3 3.7 0.0 2.3 4.2 0.5 0.0 1.8 0.6 2.4 1.1 2.0 6.6 3.6 6.1 3.3 2.6 6.9 4.1 1.6 3.8 1.2 0.7 2.3 1.2 0.0 10.8 2.6 2.0 0.8 0.7 0.6 0.6 1.3 7.2 6.5 0.1 2.4 1.0 8.5 3.4 2.4 1.1 0.7 2.7 1.0 1.0 2.4 12.8 0.3 0.0 4.6 2.3 1.0 2.4 2.5 0.6 1.1 2.9 1.1 1.8 2.8 TMEM196 MGC42090 ENSG00000173452 "Transmembrane protein 196" Q5HYL7 7 19719315-19773617 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 10.4;retina: 21.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 116.4;Endometrial stromal cells: 90.9;Excitatory neurons: 45.1;Inhibitory neurons: 23.9;Oligodendrocyte precursor cells: 127.6" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 4.8;ASC TERT1: 4.5" "Low region specificity" "Detected in many" HPA043163 Uncertain Uncertain "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Golgi apparatus" "HPA043163: AB_10794772" "unprognostic (6.08e-3)" "unprognostic (1.88e-2)" "unprognostic (2.14e-2)" "unprognostic (9.30e-2)" "unprognostic (5.63e-2)" 0.3 1.3 2.6 0.0 4.4 0.0 0.0 0.0 4.1 0.4 0.0 0.1 0.0 1.4 0.4 0.0 0.3 0.0 0.0 2.7 10.4 0.0 0.0 0.0 0.0 3.6 6.7 0.0 1.1 0.0 3.7 0.0 3.3 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.7 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.4 0.0 4.8 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.4 0.0 4.1 2.7 10.4 3.6 6.7 3.3 1.9 7.1 1.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 116.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 90.9 0.4 0.0 0.0 45.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 3.3 23.9 0.0 0.0 0.0 0.0 0.0 2.8 0.2 0.0 1.9 0.0 2.6 0.0 127.6 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TMEM199 "C17orf32, MGC45714, VMA12, VPH2" ENSG00000244045 "Transmembrane protein 199" Q8N511 17 28357642-28363683 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027051 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" "HPA027051: AB_10600915" "unprognostic (3.01e-1)" "unprognostic (3.45e-2)" "unprognostic (3.14e-1)" "prognostic unfavorable (5.55e-4)" "unprognostic (9.98e-2)" "unprognostic (4.60e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.67e-2)" "unprognostic (5.26e-2)" "unprognostic (1.78e-1)" "unprognostic (6.38e-3)" "unprognostic (1.09e-1)" "unprognostic (9.25e-2)" "unprognostic (2.75e-1)" "unprognostic (1.99e-1)" "unprognostic (3.51e-3)" "unprognostic (5.95e-2)" 8.3 11.9 9.2 10.3 10.4 13.3 8.6 10.1 13.0 9.1 9.6 9.0 7.4 9.5 9.6 10.6 8.0 6.2 9.3 9.5 10.5 12.9 14.4 8.5 12.7 10.2 10.1 8.0 8.9 15.5 11.7 9.5 10.1 9.8 7.9 13.9 9.5 6.8 7.2 11.6 9.0 6.2 9.5 13.2 8.9 7.8 10.4 12.8 10.8 7.5 11.2 8.8 8.8 12.0 12.2 20.4 19.6 16.7 7.9 6.8 16.5 14.8 9.5 20.6 18.5 48.9 9.6 17.6 14.8 11.0 26.4 20.6 21.8 13.9 18.0 32.8 19.6 13.0 17.7 23.6 15.9 18.7 22.0 9.7 12.6 19.6 13.0 12.2 10.2 16.1 21.6 21.8 15.4 24.1 21.3 25.6 16.2 21.0 13.9 17.2 24.4 16.3 15.5 20.2 24.8 26.0 17.8 45.6 27.1 20.1 28.7 16.9 14.0 17.4 13.5 15.0 25.3 29.3 38.9 16.2 21.6 11.4 22.2 28.5 24.2 20.0 15.1 25.2 16.6 17.1 13.1 13.4 20.0 16.0 16.4 14.5 18.9 15.6 23.0 14.0 14.9 19.1 9.2 10.4 10.1 13.0 9.5 10.5 10.2 10.1 10.1 9.5 10.4 12.0 12.4 32.1 8.6 8.8 21.0 5.7 10.5 34.3 15.4 13.8 14.3 14.4 5.6 12.8 23.5 9.2 8.4 40.2 15.5 21.1 43.0 40.2 3.7 12.0 11.4 14.6 15.6 12.2 11.0 31.4 38.1 10.6 7.7 10.9 7.6 11.9 17.5 26.8 51.3 11.8 10.5 15.7 32.6 22.9 9.5 4.5 11.5 22.4 21.4 6.5 45.0 19.1 25.7 7.5 13.7 35.4 19.4 6.4 15.1 13.1 20.3 54.0 15.1 14.0 13.1 8.6 14.2 26.5 35.4 14.0 8.8 48.4 15.2 14.7 13.0 11.4 TMEM202 FLJ27523 ENSG00000187806 "Transmembrane protein 202" A6NGA9 15 72398302-72408367 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 116 "testis: 12.3" "Group enriched" "Detected in some" 34 "Early spermatids: 67.6;Late spermatids: 58.5;Spermatocytes: 61.2" "Cancer enriched" "Detected in single" 11 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.31e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 67.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 61.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM205 "MBC3205, UNQ501" ENSG00000105518 "Transmembrane protein 205" Q6UW68 19 11342776-11346518 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 405.8;Hepatocytes: 520.1;Late spermatids: 662.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041504 Approved Approved "Nucleoplasm,Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "Nucleoplasm, Nuclear membrane" "HPA041504: AB_10795595" "unprognostic (2.54e-2)" "unprognostic (2.60e-2)" "unprognostic (7.19e-2)" "unprognostic (1.57e-2)" "unprognostic (6.83e-2)" "unprognostic (1.80e-1)" "unprognostic (5.04e-3)" "unprognostic (3.77e-2)" "unprognostic (1.01e-2)" "unprognostic (5.56e-3)" "unprognostic (2.70e-2)" "unprognostic (1.19e-1)" "unprognostic (8.10e-2)" "unprognostic (5.78e-2)" "unprognostic (8.18e-2)" "unprognostic (1.20e-1)" "unprognostic (1.45e-1)" 70.3 177.5 111.5 36.8 113.2 55.2 76.0 110.7 142.9 92.8 135.4 73.8 62.3 69.5 92.6 53.7 85.2 61.1 119.7 117.2 122.4 139.2 276.9 73.9 38.9 112.8 113.1 86.8 155.0 210.0 97.4 53.6 114.0 93.2 36.4 25.9 92.4 78.7 122.2 74.3 57.2 42.2 113.6 62.6 86.3 78.8 113.6 39.3 132.1 66.0 34.1 92.4 64.0 122.7 95.5 229.7 28.5 96.2 54.1 64.5 52.6 35.2 80.9 75.9 59.4 70.0 29.5 84.7 209.3 71.6 74.5 95.6 40.5 106.6 50.5 100.7 39.2 23.0 76.5 117.7 135.9 38.9 69.8 61.3 106.7 48.7 81.0 78.5 92.3 79.9 70.4 349.8 47.0 238.8 58.6 108.9 49.9 123.0 174.5 54.3 43.4 225.9 186.9 169.0 50.2 76.7 37.3 151.1 88.1 33.1 132.2 111.3 54.0 94.3 36.2 104.4 80.2 207.0 225.3 51.5 90.4 172.2 74.0 31.8 336.5 36.7 67.2 150.0 67.9 112.7 54.7 58.5 208.2 95.8 43.9 52.2 52.6 55.8 91.0 150.9 73.7 175.8 111.5 113.2 110.7 142.9 117.2 122.4 112.8 113.1 114.0 113.6 113.6 122.7 80.5 67.3 70.5 40.1 44.1 51.5 135.9 281.3 62.0 32.5 113.3 134.4 68.5 175.8 202.3 152.6 12.5 123.7 27.7 53.7 60.7 159.2 405.8 63.2 65.8 72.4 117.6 14.5 30.8 162.7 83.0 76.4 26.0 97.0 29.2 45.4 69.3 520.1 94.4 26.9 27.3 81.4 136.3 67.5 50.0 662.3 80.8 61.2 96.0 5.6 62.1 91.9 19.6 17.6 22.2 97.7 68.6 68.1 70.7 136.7 104.1 224.6 69.3 33.1 46.0 76.3 70.9 38.1 15.6 46.4 54.0 96.7 29.8 101.6 79.3 130.9 TMEM213 ENSG00000214128 "Transmembrane protein 213" A2RRL7 7 138797952-138838101 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 12 "kidney: 76.0;salivary gland: 52.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 53.3;Distal tubular cells: 144.8;Melanocytes: 26.6" "Cancer enriched" "Detected in some" 22 "renal cancer: 21.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 2.1;neutrophil: 1.1;NK-cell: 2.0" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.0" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA054059 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA054059: AB_2682361" "unprognostic (2.79e-2)" "unprognostic (2.56e-1)" "unprognostic (1.85e-2)" "unprognostic (1.19e-2)" "unprognostic (3.19e-2)" "unprognostic (6.84e-2)" "unprognostic (1.17e-2)" "unprognostic (2.10e-1)" "unprognostic (6.14e-2)" "unprognostic (6.08e-2)" "unprognostic (1.91e-2)" "prognostic favorable (5.54e-7)" "unprognostic (4.33e-1)" "unprognostic (9.99e-2)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" 0.1 0.1 0.5 0.2 0.5 1.1 4.7 0.6 0.7 2.8 0.4 0.1 1.3 0.2 0.6 0.3 0.1 0.2 0.0 0.6 0.1 76.0 0.1 1.1 0.2 0.2 0.1 0.1 0.6 0.0 0.1 0.1 0.4 0.4 0.1 0.3 52.3 1.2 0.1 5.3 0.3 0.1 0.0 0.2 0.4 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.1 2.1 0.2 0.2 0.3 0.2 0.4 0.2 0.1 0.2 0.1 0.3 0.2 0.1 1.1 2.0 0.2 0.2 0.1 0.1 0.5 0.5 0.6 0.7 0.6 0.1 0.2 0.1 0.4 0.0 0.5 1.0 0.1 3.2 9.9 0.0 0.1 0.0 0.9 3.0 0.0 0.4 14.1 7.9 0.4 0.0 4.4 53.3 0.0 0.0 0.2 0.0 144.8 0.0 0.0 0.9 0.4 0.5 0.0 0.0 0.6 0.2 0.1 0.2 0.0 1.3 1.3 0.1 0.0 0.0 0.1 1.7 0.4 0.0 2.0 0.0 0.8 0.0 0.0 0.1 26.6 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.9 3.5 1.3 0.0 0.5 0.2 0.0 0.2 0.0 0.4 0.0 0.6 0.0 0.2 0.6 TMEM214 FLJ20254 ENSG00000119777 "Transmembrane protein 214" Q6NUQ4 2 27032910-27041694 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034551 Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Golgi apparatus, Cytosol" "HPA034551: AB_10602481" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.10e-1)" "unprognostic (4.12e-3)" "unprognostic (1.90e-2)" "unprognostic (2.42e-2)" "prognostic unfavorable (4.96e-4)" "unprognostic (1.96e-1)" "unprognostic (3.70e-1)" "unprognostic (2.40e-1)" "unprognostic (1.96e-1)" "unprognostic (2.74e-2)" "prognostic unfavorable (2.39e-10)" "unprognostic (1.54e-2)" "unprognostic (1.97e-2)" "unprognostic (2.04e-1)" "unprognostic (2.92e-2)" 45.8 39.0 14.7 30.8 15.8 23.1 43.2 15.3 17.3 45.0 28.7 38.3 30.5 43.7 66.2 31.5 37.5 30.7 36.7 14.8 17.0 30.0 46.5 37.7 25.1 19.1 18.7 41.4 79.9 56.0 60.4 45.8 18.3 37.9 41.7 8.8 83.6 44.4 35.7 37.8 33.6 45.1 15.6 37.4 40.8 19.5 17.8 21.7 42.3 21.3 34.4 36.7 33.9 14.9 82.4 53.5 32.2 68.2 102.8 103.7 69.4 105.9 142.4 76.0 85.2 53.0 67.3 37.6 52.4 156.6 59.7 57.6 39.3 74.9 61.0 36.3 44.1 49.9 41.4 109.8 128.1 45.7 82.5 90.4 52.7 66.8 112.0 58.6 83.5 24.3 46.0 75.3 85.9 59.6 23.3 34.1 23.1 110.0 42.8 31.3 58.5 91.0 57.1 57.0 27.8 32.3 49.4 83.3 38.2 31.0 45.9 27.0 72.4 55.2 52.8 57.0 60.4 100.9 73.3 59.2 71.1 56.8 77.9 5.7 3.5 2.8 3.9 3.8 5.0 2.5 3.0 2.8 2.8 2.8 1.5 2.1 0.6 5.6 2.2 5.0 2.6 2.5 14.7 15.8 15.3 17.3 14.8 17.0 19.1 18.7 18.3 15.6 17.8 14.9 15.8 3.2 20.1 3.9 18.5 7.6 9.6 10.4 3.4 9.3 19.8 11.0 8.2 21.5 15.0 14.7 10.4 43.6 15.0 37.5 1.9 24.7 6.4 11.3 25.4 17.5 17.9 18.5 4.8 34.6 62.9 26.9 33.1 23.8 14.5 17.0 32.5 28.9 27.3 6.7 4.4 37.6 10.2 18.9 12.8 7.8 32.6 11.7 5.4 6.5 14.6 6.9 14.4 4.0 3.8 21.7 22.3 20.3 63.0 20.8 25.4 10.4 11.0 8.4 26.3 11.6 19.6 24.4 12.7 8.4 9.2 71.7 12.0 17.6 27.6 15.8 TMEM218 ENSG00000150433 "Transmembrane protein 218" A2RU14 11 125096545-125111763 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038489 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA038489: AB_10672748" "unprognostic (3.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.60e-2)" "unprognostic (2.41e-3)" "unprognostic (8.86e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.63e-2)" "unprognostic (7.09e-3)" "unprognostic (2.18e-1)" "unprognostic (6.45e-2)" "unprognostic (1.09e-1)" "unprognostic (9.95e-2)" "prognostic favorable (5.50e-4)" "unprognostic (6.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.72e-2)" 17.7 18.1 4.8 9.5 5.5 5.3 14.0 5.3 6.5 15.5 5.3 13.5 8.4 16.6 6.9 11.6 14.8 7.4 10.2 4.6 5.4 12.7 12.9 12.0 10.5 6.0 5.5 15.0 14.5 10.3 15.2 5.9 5.8 13.0 6.0 6.5 10.9 6.8 9.2 8.9 11.8 8.3 5.7 16.6 13.2 5.6 5.1 8.4 10.9 5.7 7.0 13.8 13.2 6.3 12.5 24.0 14.9 18.2 13.5 18.6 9.0 12.2 9.2 9.3 12.0 2.5 35.9 15.6 29.9 7.5 14.2 14.2 9.4 11.6 12.2 22.0 13.5 35.1 6.1 10.0 13.3 11.1 12.6 14.7 15.2 16.5 19.6 14.9 13.7 19.1 14.4 19.4 16.2 6.4 2.9 23.3 12.2 34.0 22.6 16.3 18.0 12.0 8.3 12.3 12.9 19.4 16.6 6.6 9.1 8.7 31.3 15.7 17.6 11.4 10.3 13.4 13.5 11.1 10.1 12.9 9.1 22.9 20.3 43.7 40.1 17.4 21.6 31.6 18.7 29.6 20.5 20.5 47.4 23.9 17.2 20.4 15.7 32.5 30.9 41.1 20.5 27.0 4.8 5.5 5.3 6.5 4.6 5.4 6.0 5.5 5.8 5.7 5.1 6.3 21.0 19.2 13.4 7.8 17.8 12.1 19.6 34.6 19.4 7.0 22.1 24.6 8.1 15.7 16.6 14.7 0.0 28.0 18.1 5.7 27.4 20.5 3.4 23.1 22.4 15.8 10.8 14.5 4.4 16.2 18.4 21.1 8.6 10.6 3.8 22.2 18.5 15.1 42.2 23.5 7.4 11.7 20.3 21.0 17.5 1.9 10.2 21.9 17.8 14.0 26.0 26.0 18.6 9.5 11.2 13.1 3.9 16.6 15.8 9.4 8.5 19.7 29.4 12.4 26.3 16.7 18.3 16.6 13.8 18.0 14.2 9.7 14.5 27.0 13.7 16.6 TMEM240 "C1orf70, SCA21" ENSG00000205090 "Transmembrane protein 240" Q5SV17 1 1534778-1540624 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 6.5;Excitatory neurons: 15.5;Inhibitory neurons: 15.1;Oligodendrocyte precursor cells: 8.0;Sertoli cells: 6.6" "Cancer enhanced" "Detected in many" "glioma: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 8.5;SCLC-21H: 9.3;SH-SY5Y: 11.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066721 Supported NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA066721: AB_2732750" "unprognostic (2.24e-1)" "unprognostic (1.87e-1)" "unprognostic (5.52e-5)" "unprognostic (2.31e-1)" "unprognostic (2.47e-1)" "unprognostic (1.01e-1)" "unprognostic (1.37e-1)" "unprognostic (3.85e-2)" "unprognostic (3.48e-2)" "unprognostic (1.21e-1)" "prognostic favorable (2.52e-4)" "unprognostic (9.13e-2)" "unprognostic (7.96e-3)" "unprognostic (9.50e-4)" "unprognostic (2.64e-1)" "unprognostic (8.38e-2)" "unprognostic (1.93e-1)" 4.1 3.5 10.9 0.6 12.2 0.1 3.9 17.1 22.8 14.8 2.5 17.4 0.4 15.1 0.9 2.9 10.6 1.0 8.2 13.1 7.6 3.6 1.2 4.2 0.4 7.1 8.1 16.1 1.3 1.4 15.1 1.6 7.3 9.5 0.5 1.3 2.5 3.3 3.8 2.7 4.9 2.1 5.4 4.0 5.7 3.0 8.5 0.3 5.3 1.2 0.2 10.8 8.6 9.6 0.9 1.0 5.7 0.7 0.8 3.8 1.4 3.8 2.1 3.5 2.0 0.0 0.4 0.7 0.7 1.9 0.2 2.2 0.0 0.2 0.5 3.5 8.5 0.5 3.6 1.3 7.5 0.0 0.8 5.2 1.8 1.4 0.3 4.3 3.5 0.6 1.1 0.3 0.0 0.2 0.6 0.9 3.9 0.1 1.2 3.3 1.1 0.7 0.4 0.0 9.3 11.2 1.4 0.4 4.0 0.1 0.6 0.0 1.9 0.5 1.7 0.7 1.7 1.6 0.4 0.4 1.9 2.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 12.2 17.1 22.8 13.1 7.6 7.1 8.1 7.3 5.4 8.5 9.6 0.7 0.0 0.0 6.5 0.2 0.0 0.3 0.0 1.2 3.1 0.4 0.5 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.2 1.6 0.4 0.0 0.0 15.5 0.0 0.1 0.8 0.0 0.2 0.0 1.6 0.7 0.0 0.1 3.3 15.1 0.6 0.0 0.0 0.0 0.0 1.2 0.2 0.0 1.0 0.0 4.5 1.0 8.0 4.4 0.1 0.2 2.2 0.3 0.2 0.1 0.1 0.0 0.5 6.6 0.2 0.9 0.1 0.5 0.1 0.0 0.0 0.2 1.4 0.3 0.1 TMEM25 FLJ14399 ENSG00000149582 "Transmembrane protein 25" Q86YD3 11 118531041-118547280 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 149.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 35.9;SK-BR-3: 33.7;T-47d: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA012163, HPA051562" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 6900000 "Cluster 48: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus, Vesicles" "HPA012163: AB_1858112, HPA051562: AB_2681535" "unprognostic (1.53e-2)" "unprognostic (7.18e-2)" "unprognostic (2.43e-1)" "unprognostic (6.69e-2)" "unprognostic (3.61e-1)" "unprognostic (6.50e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-3)" "unprognostic (1.58e-1)" "unprognostic (3.42e-1)" "unprognostic (1.66e-2)" "unprognostic (8.19e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.15e-1)" "unprognostic (2.51e-1)" "unprognostic (1.26e-1)" "unprognostic (7.01e-2)" 6.9 25.3 35.0 3.8 36.0 2.2 14.6 33.9 44.3 14.9 32.2 16.0 46.0 15.3 25.7 11.1 13.7 8.9 8.9 37.5 36.7 18.6 23.1 9.9 4.8 32.1 30.3 23.4 17.6 23.3 29.5 6.0 32.0 15.7 3.7 22.3 21.0 18.3 18.5 8.7 35.2 10.8 31.5 5.3 13.3 6.5 35.1 5.1 15.9 9.9 5.3 14.4 11.6 35.1 3.4 0.7 5.8 9.5 6.0 0.9 5.6 5.2 9.9 4.9 9.8 27.1 18.8 0.3 20.1 5.3 10.9 14.8 0.0 18.3 4.4 11.9 11.1 0.5 5.4 6.0 16.0 0.3 0.5 7.3 10.9 5.3 0.9 35.9 7.2 13.7 2.6 11.7 4.9 4.1 6.0 0.5 4.9 0.1 12.8 8.1 4.2 12.3 25.3 0.3 17.0 11.5 5.1 33.7 0.1 8.7 43.8 0.6 2.5 2.1 10.6 0.4 1.6 11.7 8.3 3.1 0.4 0.2 0.2 0.7 0.2 0.2 5.1 0.2 7.1 4.0 7.3 2.9 0.5 2.6 10.0 5.4 0.4 7.4 0.2 3.4 6.0 3.5 35.0 36.0 33.9 44.3 37.5 36.7 32.1 30.3 32.0 31.5 35.1 35.1 5.1 6.4 3.9 11.1 6.2 5.7 10.7 14.7 13.1 27.7 27.7 30.6 6.1 14.3 9.3 16.5 29.2 37.1 4.8 0.9 11.7 16.6 2.8 4.1 5.0 6.4 11.4 5.2 20.1 6.4 16.9 8.7 2.6 5.5 8.9 18.0 3.6 9.6 2.9 11.8 22.0 7.8 10.2 0.0 1.9 5.5 23.3 1.1 7.2 2.8 3.4 28.8 5.2 8.5 6.5 5.0 5.5 23.3 5.5 5.5 149.1 25.6 7.4 41.1 0.0 12.1 7.5 3.9 5.2 4.0 3.7 16.3 4.7 15.3 15.0 5.7 TMEM256 "C17orf61, MGC40107" ENSG00000205544 "Transmembrane protein 256" Q8N2U0 17 7402975-7404097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 573.1;Proximal enterocytes: 972.0;Proximal tubular cells: 801.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062732 Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA062732: AB_2684852" "unprognostic (3.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (2.77e-2)" "unprognostic (1.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.69e-2)" "unprognostic (5.73e-2)" "unprognostic (7.45e-2)" "unprognostic (2.12e-2)" "unprognostic (3.22e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.36e-4)" "unprognostic (1.12e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.19e-2)" 92.2 84.3 63.9 22.2 66.4 36.7 86.7 67.7 73.0 85.6 63.5 72.6 76.3 63.5 48.2 74.7 77.6 24.0 99.8 62.1 65.2 122.4 173.9 51.8 34.5 67.3 64.2 75.4 113.8 42.6 45.9 14.3 67.1 81.5 25.2 15.1 60.3 24.4 67.4 64.3 90.0 17.6 67.6 67.9 91.7 12.4 64.5 30.8 51.5 41.6 28.5 69.7 67.6 72.4 67.0 89.3 47.3 64.3 78.6 99.0 43.0 30.7 43.9 49.4 46.3 36.1 38.0 59.0 54.0 31.2 39.4 56.4 29.9 93.6 35.7 30.5 99.4 37.5 32.0 95.1 54.0 13.0 49.0 87.1 44.2 64.1 53.0 66.4 73.1 63.8 28.9 39.1 64.1 36.5 44.1 42.5 21.4 29.4 58.6 69.9 41.5 68.8 121.2 28.8 5.5 37.9 47.6 36.7 51.2 46.0 66.6 23.4 43.7 22.8 42.7 46.5 39.3 32.6 45.2 31.2 60.2 18.0 44.4 12.9 63.1 14.8 35.7 48.5 44.5 77.4 42.3 41.3 59.7 69.0 48.5 45.2 3.9 39.3 36.3 82.3 46.0 77.8 63.9 66.4 67.7 73.0 62.1 65.2 67.3 64.2 67.1 67.6 64.5 72.4 103.1 44.8 55.8 0.0 134.5 87.4 93.3 100.1 94.4 24.0 212.4 216.9 62.5 131.5 76.9 132.4 8.4 77.2 78.4 162.9 297.4 132.8 6.0 80.2 84.6 85.1 125.3 100.5 0.0 190.8 223.6 83.3 88.7 84.5 68.4 50.3 114.5 573.1 205.5 20.2 0.0 186.6 81.4 164.7 128.2 6.8 137.3 108.4 144.1 0.0 166.7 134.0 88.6 0.0 0.0 171.3 214.0 71.1 173.1 87.3 972.0 801.9 96.3 42.0 59.2 80.2 160.2 10.1 39.1 179.5 134.0 46.7 91.7 64.5 210.0 90.9 TMEM272 "FLJ37307, LINC00282, NCRNA00282" ENSG00000281106 "Transmembrane protein 272" A0A1B0GTI8 13 51813347-51845177 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 15.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "amygdala: 4.2;basal ganglia: 15.9;cerebral cortex: 10.0" "Immune cell enriched" "Detected in single" 89 "neutrophil: 40.1" "Lineage enriched" "Detected in single" 89 "granulocytes: 40.1" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.6" "Low region specificity" "Detected in many" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (2.27e-2)" "unprognostic (2.50e-1)" "unprognostic (5.12e-2)" "unprognostic (8.71e-7)" "unprognostic (4.52e-2)" "unprognostic (1.78e-4)" "unprognostic (6.16e-2)" "unprognostic (5.19e-2)" "unprognostic (8.88e-2)" "unprognostic (2.02e-1)" "unprognostic (3.73e-3)" "unprognostic (1.32e-5)" "unprognostic (2.12e-2)" "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.45e-1)" "unprognostic (1.58e-2)" 0.1 0.0 4.2 1.0 15.9 1.0 0.1 1.1 10.0 0.0 0.0 0.1 0.4 0.3 0.1 0.1 0.0 0.2 1.8 2.1 1.7 0.1 0.3 0.1 1.1 0.5 1.1 0.1 0.4 0.0 0.6 0.2 0.6 0.0 0.1 2.9 0.1 0.0 0.5 0.6 0.5 0.0 0.2 0.6 0.1 0.5 2.0 0.7 0.0 0.4 0.9 0.0 0.0 1.1 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 40.1 0.0 0.0 0.0 0.0 0.0 4.2 15.9 1.1 10.0 2.1 1.7 0.5 1.1 0.6 0.2 2.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM38B "bA219P18.1, C9orf87, D4Ertd89e, FLJ10493, TRIC-B" ENSG00000095209 "Transmembrane protein 38B" Q9NVV0 9 105694541-105776629 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 77.4;tongue: 62.1" "Cell type enhanced" "Detected in many" "Early spermatids: 267.0;Late spermatids: 488.4;Spermatocytes: 157.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018465 Uncertain NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" "HPA018465: AB_1858116" "unprognostic (3.34e-1)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (2.68e-1)" "unprognostic (7.20e-2)" "unprognostic (1.51e-2)" "unprognostic (3.11e-3)" "unprognostic (1.88e-2)" "unprognostic (3.54e-2)" "unprognostic (5.82e-3)" "unprognostic (5.80e-2)" "prognostic favorable (7.96e-4)" "unprognostic (1.09e-1)" "unprognostic (2.09e-1)" "unprognostic (3.89e-3)" "unprognostic (9.98e-2)" 7.6 14.0 6.2 7.1 11.6 19.1 4.7 19.5 9.2 7.6 6.3 12.5 6.4 8.3 17.3 7.2 7.2 6.8 30.7 7.4 12.9 29.2 15.3 5.7 8.1 8.3 8.4 18.3 4.9 9.2 5.8 4.6 10.6 8.0 11.8 10.4 4.0 6.8 77.4 6.0 10.7 8.1 5.9 6.3 6.7 28.6 9.0 4.9 28.8 62.1 5.1 5.0 4.0 19.6 16.7 25.6 19.6 30.9 110.5 24.3 40.8 23.4 15.3 22.6 23.3 40.0 22.5 38.4 11.8 8.5 36.4 11.6 28.4 13.5 24.4 29.0 37.8 15.8 16.2 24.7 15.1 48.1 32.7 23.0 11.8 15.5 21.6 7.1 9.1 26.6 84.3 33.2 14.0 46.4 33.6 14.5 15.1 48.7 27.1 22.3 61.4 18.4 10.3 13.2 34.1 8.3 24.2 39.4 17.9 13.0 49.2 33.5 4.9 20.5 20.2 78.9 24.7 40.7 109.8 19.1 38.2 52.2 41.7 15.6 20.2 53.8 13.2 29.6 17.7 56.6 18.3 15.8 23.3 56.6 38.9 24.9 3.1 28.2 26.8 51.7 18.0 24.2 6.2 11.6 19.5 9.2 7.4 12.9 8.3 8.4 10.6 5.9 9.0 19.6 9.2 0.0 2.7 7.5 27.8 30.3 24.9 6.2 15.9 12.9 8.9 3.9 55.5 15.7 8.4 25.8 29.2 12.0 16.4 19.1 66.5 8.9 267.0 2.2 7.2 9.9 31.8 7.2 12.4 6.9 19.0 24.2 9.2 3.0 15.8 11.3 3.6 24.4 30.9 11.8 28.6 12.9 18.3 7.9 33.2 488.4 85.1 21.4 32.0 6.5 18.3 30.6 3.1 65.4 30.6 6.3 12.2 44.8 20.2 55.1 10.9 47.0 7.6 12.3 118.3 18.2 58.1 157.8 47.6 13.0 32.7 21.2 13.8 39.7 19.0 20.2 TMEM44 DKFZp686O18124 ENSG00000145014 "Transmembrane protein 44" Q2T9K0 3 194587673-194633689 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.2;Hepatic stellate cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 3.7;NK-cell: 8.1" "Group enriched" "Detected in many" 10 "granulocytes: 3.7;NK-cells: 8.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043718 Uncertain Approved Cytosol "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA043718: AB_10794662" "unprognostic (8.94e-2)" "unprognostic (1.01e-1)" "unprognostic (8.31e-3)" "unprognostic (4.53e-2)" "unprognostic (2.78e-3)" "unprognostic (9.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.17e-2)" "unprognostic (1.70e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-2)" "unprognostic (4.75e-3)" "prognostic unfavorable (6.55e-13)" "unprognostic (1.23e-2)" "unprognostic (3.36e-1)" "unprognostic (1.65e-3)" "unprognostic (5.66e-2)" 10.3 2.9 9.8 2.3 11.7 5.2 8.9 7.8 12.4 6.9 7.1 11.0 2.7 5.6 13.7 5.6 5.4 4.5 9.6 10.3 10.1 6.0 3.4 11.3 3.0 9.9 9.7 4.9 3.5 0.9 2.6 7.4 10.0 5.2 7.2 0.6 7.7 2.2 3.2 3.6 6.8 3.2 8.8 9.3 4.9 2.2 10.5 2.0 5.6 2.3 1.6 5.3 5.9 9.2 11.1 9.1 13.4 14.2 4.8 16.2 11.8 8.2 15.3 6.8 10.8 5.0 21.8 2.0 38.9 10.0 20.3 12.6 4.5 6.4 4.6 18.1 6.3 12.4 10.6 3.8 8.7 3.9 18.9 10.0 6.8 15.4 6.8 32.8 28.2 12.1 3.4 0.5 22.9 10.1 5.9 9.9 6.9 11.1 14.8 11.5 8.4 0.3 7.2 6.3 3.7 7.7 6.1 1.9 12.6 5.6 9.0 8.5 33.7 20.8 7.6 6.4 11.2 1.5 1.2 4.0 31.4 15.0 10.4 3.7 0.2 0.2 0.4 0.1 0.0 0.1 0.1 0.6 0.0 0.2 0.0 0.2 0.4 8.1 0.3 0.4 0.0 0.0 9.8 11.7 7.8 12.4 10.3 10.1 9.9 9.7 10.0 8.8 10.5 9.2 22.0 0.0 2.3 3.3 2.1 0.5 3.3 4.9 1.8 0.9 2.8 2.3 1.7 1.5 6.0 5.5 2.1 9.5 1.7 31.2 0.0 5.7 0.6 2.3 3.7 23.8 6.0 4.0 12.7 4.9 4.0 6.0 22.4 2.0 17.7 10.6 53.2 0.6 3.5 0.0 5.4 25.2 6.1 1.3 3.4 0.3 3.1 1.5 1.8 12.2 0.1 0.5 2.1 2.5 1.5 14.9 21.0 1.9 1.3 6.0 3.9 0.4 7.5 0.6 6.6 1.8 3.6 0.5 6.5 2.4 0.6 8.8 1.9 6.0 21.0 6.3 TMEM52 ENSG00000178821 "Transmembrane protein 52" Q8NDY8 1 1917590-1919279 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "pancreas: 216.2;skeletal muscle: 298.9;tongue: 207.8" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 22.3;Hepatocytes: 25.9;Spermatocytes: 34.6;Spermatogonia: 39.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 20.5;OE19: 18.2;RPMI-8226: 37.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA079372 Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" Nucleoplasm "HPA079372: " "unprognostic (4.39e-2)" "unprognostic (2.60e-1)" "unprognostic (3.76e-2)" "unprognostic (7.35e-3)" "unprognostic (1.04e-5)" "unprognostic (1.46e-1)" "unprognostic (6.71e-3)" "unprognostic (3.68e-2)" "unprognostic (9.49e-2)" "unprognostic (1.69e-1)" "unprognostic (3.83e-3)" "unprognostic (5.80e-2)" "unprognostic (8.95e-2)" "unprognostic (1.18e-1)" "unprognostic (2.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.18e-2)" 1.9 52.6 1.9 0.2 2.1 0.5 2.0 2.1 3.7 1.1 3.0 2.5 3.6 0.6 0.4 6.9 3.3 0.4 1.8 1.8 1.9 2.4 13.5 1.9 0.4 1.8 2.1 2.2 216.2 3.1 1.7 0.2 1.7 1.8 1.3 0.2 19.8 0.4 298.9 3.5 2.3 0.3 1.5 2.8 6.9 29.2 1.8 0.4 0.8 207.8 0.3 0.6 2.1 1.7 3.4 0.3 0.9 1.8 0.3 0.1 7.5 0.5 0.2 2.2 1.3 5.6 2.3 0.8 2.2 3.5 0.8 1.1 5.5 1.5 0.4 0.4 4.0 0.0 0.9 20.5 1.1 0.0 1.3 0.1 3.1 0.7 0.3 0.1 0.1 3.9 5.1 1.9 0.0 6.4 0.5 1.5 2.9 18.2 10.6 1.5 0.0 37.1 1.2 0.2 3.7 2.6 0.0 3.1 0.4 1.3 2.1 0.4 0.0 0.0 1.4 1.0 0.0 2.4 0.8 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 2.1 2.1 3.7 1.8 1.9 1.8 2.1 1.7 1.5 1.8 1.7 0.4 0.0 0.0 0.0 1.2 4.5 2.9 1.2 2.8 0.4 3.9 5.2 0.8 8.6 2.4 0.0 0.0 1.9 0.8 6.8 1.9 1.8 3.9 3.8 0.3 0.8 0.0 0.4 0.6 22.3 7.0 1.6 5.1 0.8 0.0 5.1 0.7 25.9 0.6 0.0 0.5 11.1 8.2 0.8 2.2 5.8 14.9 0.7 8.8 0.0 0.6 1.8 0.0 0.0 0.1 6.7 2.5 9.8 4.3 14.2 15.4 11.5 8.7 1.0 0.0 15.4 1.6 34.6 39.4 2.5 2.8 3.7 1.2 15.5 7.1 3.1 TMEM52B "C12orf59, FLJ31166" ENSG00000165685 "Transmembrane protein 52B" Q4KMG9 12 10170542-10191801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "kidney: 175.8" "Cell type enriched" "Detected in some" 15 "Distal tubular cells: 712.1" "Cancer enriched" "Detected in some" 5 "renal cancer: 6.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "CACO-2: 95.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA058096 Enhanced Approved "Focal adhesion sites" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Focal adhesion sites" "HPA058096: AB_2683603" "unprognostic (1.10e-2)" "unprognostic (7.61e-2)" "unprognostic (1.37e-3)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" "unprognostic (5.33e-3)" "unprognostic (1.37e-1)" "unprognostic (8.65e-2)" "unprognostic (7.14e-4)" "unprognostic (2.23e-1)" "unprognostic (6.36e-2)" "unprognostic (7.33e-2)" "unprognostic (3.24e-2)" "unprognostic (5.80e-2)" "unprognostic (5.51e-2)" "unprognostic (1.66e-1)" "unprognostic (3.18e-1)" 0.1 0.1 0.6 0.8 0.9 3.4 0.3 0.8 0.9 0.1 0.9 0.1 0.2 0.0 0.3 0.0 0.1 0.4 0.0 0.7 0.7 175.8 0.2 0.7 0.2 1.3 0.8 0.0 0.3 0.1 0.0 6.0 1.2 0.1 0.1 0.1 1.9 0.0 0.0 0.4 0.2 0.4 1.0 0.1 0.4 0.3 1.2 0.1 0.2 0.0 0.2 0.2 0.0 1.6 2.3 0.1 0.0 0.1 0.0 0.0 1.1 2.2 0.0 0.1 0.0 95.9 0.1 0.0 0.1 0.7 4.9 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 11.7 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.0 0.0 7.0 8.9 0.0 3.0 5.0 1.4 0.0 0.2 0.4 0.0 0.0 0.1 0.1 0.1 0.2 4.7 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.6 0.9 0.8 0.9 0.7 0.7 1.3 0.8 1.2 1.0 1.2 1.6 0.1 0.0 0.5 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.3 0.0 0.0 12.9 0.0 44.7 0.0 0.1 712.1 0.0 0.6 0.0 0.1 0.2 0.0 0.0 0.8 0.0 2.5 3.2 0.0 0.1 0.0 0.0 0.0 0.0 10.8 0.0 0.2 0.0 0.0 0.8 1.1 0.1 0.3 4.2 1.8 2.8 1.7 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 19.4 0.1 0.0 0.0 0.1 TMEM59 "C1orf8, HSPC001" ENSG00000116209 "Transmembrane protein 59" Q9BXS4 1 54026681-54053504 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075447 Approved NA NA 27000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA075447: " "unprognostic (2.63e-1)" "unprognostic (9.88e-2)" "unprognostic (2.63e-2)" "unprognostic (2.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (1.63e-2)" "unprognostic (8.28e-2)" "unprognostic (4.10e-1)" "unprognostic (6.57e-2)" "unprognostic (1.19e-1)" "unprognostic (4.49e-2)" "unprognostic (6.34e-3)" "unprognostic (9.84e-2)" "unprognostic (1.70e-1)" "unprognostic (6.83e-3)" "unprognostic (7.38e-2)" 257.6 359.7 181.9 164.6 220.8 259.7 341.4 240.3 253.8 343.6 379.5 488.3 364.1 208.7 415.5 241.8 403.2 299.3 275.7 178.4 202.0 473.7 505.7 264.0 162.6 240.6 205.0 225.4 586.1 532.5 170.2 325.8 239.1 350.2 485.3 254.2 550.3 279.9 194.5 194.7 369.1 219.8 235.7 188.7 433.0 174.9 204.6 186.9 341.3 247.6 189.2 289.2 202.6 286.8 188.9 122.3 142.8 185.2 844.1 371.1 182.8 347.9 499.1 211.5 276.0 99.1 391.9 96.7 322.6 595.6 257.7 281.1 166.2 237.5 221.9 237.7 177.4 133.5 266.6 166.1 317.8 165.7 268.7 408.3 411.2 207.5 219.2 566.9 246.6 127.8 158.9 326.3 245.1 91.6 97.9 137.3 201.0 528.3 226.3 94.0 251.6 403.2 257.6 248.0 208.2 173.3 381.5 386.0 398.3 266.2 184.9 348.4 259.3 259.8 90.7 193.3 187.8 289.0 338.7 114.5 349.4 275.4 222.3 1183.5 654.6 831.5 439.7 532.9 461.8 449.3 465.9 480.4 520.9 405.2 430.3 426.4 1196.5 430.4 595.9 527.1 576.1 1153.8 181.9 220.8 240.3 253.8 178.4 202.0 240.6 205.0 239.1 235.7 204.6 286.8 355.3 233.9 181.3 49.6 221.3 404.2 637.0 1214.2 237.3 150.2 409.0 325.1 155.1 479.0 991.8 437.7 118.9 477.7 244.5 905.2 160.4 527.8 357.1 348.5 201.9 279.5 408.2 277.0 44.3 352.5 528.7 410.6 226.8 217.2 155.2 89.5 334.4 413.2 320.2 132.9 42.1 672.8 1131.1 302.9 290.3 183.1 432.7 225.4 690.1 27.2 209.3 473.5 190.5 60.3 176.6 329.3 1064.8 354.0 692.8 583.2 1015.8 468.8 977.4 183.6 368.1 198.6 350.4 488.9 210.1 245.5 414.3 687.1 227.2 185.8 534.9 750.4 TMEM67 "JBTS6, MGC26979, MKS3, NPHP11" ENSG00000164953 "Transmembrane protein 67" Q5HYA8 8 93754844-93819234 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Deafness, Disease variant, Joubert syndrome, Meckel syndrome, Mental retardation, Nephronophthisis, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 66.7;Excitatory neurons: 59.8;Respiratory ciliated cells: 95.8;Rod photoreceptor cells: 83.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.57e-3)" "unprognostic (1.22e-1)" "unprognostic (2.45e-2)" "unprognostic (1.73e-1)" "unprognostic (5.07e-2)" "unprognostic (3.08e-1)" "unprognostic (2.25e-5)" "unprognostic (2.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.51e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (7.62e-4)" "unprognostic (8.41e-2)" "unprognostic (2.21e-1)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" 2.4 2.5 1.7 1.3 2.7 1.4 3.5 2.8 2.7 3.6 10.3 2.1 1.4 4.2 6.3 1.8 13.3 2.8 5.0 2.5 3.0 3.1 1.2 3.6 1.4 6.5 6.8 4.2 2.6 4.7 5.8 2.1 3.1 2.8 2.2 6.1 1.9 3.2 1.2 3.7 1.3 2.4 3.5 1.9 2.0 6.8 3.1 1.4 6.0 0.6 1.7 2.5 2.2 3.9 5.8 3.7 5.2 4.1 4.4 9.8 3.1 3.3 5.4 3.8 7.5 2.1 13.0 1.5 6.9 3.6 6.9 5.9 1.9 3.3 5.6 1.1 4.3 3.6 4.8 1.8 4.0 2.7 1.5 4.2 3.0 6.8 3.0 7.1 4.0 6.1 2.5 0.9 4.0 1.4 4.5 2.0 4.3 2.3 3.4 1.6 1.7 0.0 4.7 2.5 3.4 5.7 3.3 0.9 5.6 4.6 6.8 1.4 2.1 4.1 1.7 5.7 3.0 1.8 5.5 1.6 7.4 0.8 3.9 1.7 0.5 0.2 1.5 0.2 1.2 0.7 1.3 1.3 1.0 1.5 1.5 1.5 0.5 1.8 0.2 1.1 0.3 0.5 1.7 2.7 2.8 2.7 2.5 3.0 6.5 6.8 3.1 3.5 3.1 3.9 5.0 12.8 8.7 27.4 6.3 2.8 5.6 12.2 2.2 14.6 6.0 5.6 31.9 5.7 12.5 20.2 66.7 3.4 5.6 1.2 0.0 6.4 24.5 50.9 15.1 6.8 9.0 4.6 59.8 2.7 5.6 9.8 4.1 4.9 5.1 16.1 10.0 1.6 2.2 23.5 34.2 2.4 8.2 2.9 2.6 7.7 16.1 1.8 1.8 13.1 1.5 9.3 3.1 17.6 3.4 2.1 0.5 10.5 2.7 2.1 0.4 3.9 95.8 83.2 6.6 18.9 6.9 47.6 16.5 2.6 1.4 2.3 5.6 13.7 2.8 1.6 TMEM70 FLJ20533 ENSG00000175606 "Transmembrane protein 70" Q9BUB7 8 73972437-73982783 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 100.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 78.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023187, CAB034226" Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria Nucleoplasm "CAB034226: AB_2205189, HPA023187: AB_2671101" "unprognostic (2.26e-3)" "unprognostic (4.87e-1)" "unprognostic (1.38e-2)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (8.22e-3)" "unprognostic (9.17e-2)" "unprognostic (1.01e-1)" "unprognostic (7.37e-2)" "unprognostic (7.04e-2)" "unprognostic (2.88e-2)" "unprognostic (9.14e-2)" "unprognostic (3.65e-3)" "unprognostic (6.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.13e-1)" "unprognostic (2.70e-2)" 18.1 18.2 9.2 9.8 9.7 10.4 11.3 10.5 12.3 8.0 9.5 12.6 5.8 8.9 10.6 9.3 11.3 8.9 19.3 10.3 10.2 12.0 24.4 9.0 10.1 9.6 9.1 10.5 25.0 8.3 7.6 10.3 10.1 7.4 9.7 6.1 9.9 5.9 100.7 7.7 9.5 9.1 9.5 9.6 17.8 9.8 9.5 11.0 6.0 20.5 10.3 11.3 7.4 10.1 21.2 16.4 13.1 13.8 14.9 12.7 13.6 17.6 15.8 19.4 15.3 15.8 11.9 28.4 15.0 12.0 16.4 19.1 24.9 16.8 21.4 18.9 17.5 28.3 10.0 21.2 14.7 15.5 14.5 11.8 15.3 12.2 6.4 7.3 16.4 14.2 22.0 13.5 20.5 15.9 35.8 29.6 12.3 26.6 20.6 25.4 12.8 24.2 20.5 20.0 29.7 13.1 11.0 78.0 23.3 10.2 16.0 14.1 10.6 11.1 13.7 20.7 16.9 19.9 18.7 28.1 16.4 12.1 12.5 6.3 9.1 6.7 8.0 10.2 9.1 17.7 9.0 9.3 9.6 10.9 10.3 9.6 6.7 5.8 7.9 11.0 7.9 12.0 9.2 9.7 10.5 12.3 10.3 10.2 9.6 9.1 10.1 9.5 9.5 10.1 136.2 16.0 30.1 5.5 37.1 67.3 43.7 54.8 24.5 23.9 26.2 22.2 46.3 14.3 35.7 22.0 8.4 71.2 48.1 69.0 66.5 36.6 20.3 40.8 26.2 96.4 13.8 26.5 12.8 63.5 59.6 50.2 17.3 17.1 39.9 17.0 28.5 50.3 132.4 10.1 11.4 31.7 42.7 70.0 74.5 12.1 29.8 73.2 40.9 5.6 38.9 23.1 22.6 3.5 8.1 43.6 37.9 29.0 68.6 42.1 28.8 75.4 58.7 17.5 39.5 61.9 40.8 70.6 29.5 21.5 59.7 70.3 39.8 52.6 34.1 26.2 TMEM79 "FLJ16057, FLJ32254, MATT, MGC13102" ENSG00000163472 "Transmembrane protein 79" Q9BSE2 1 156282935-156293185 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 132.4;skin 1: 89.9;vagina: 59.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 24.1;Squamous epithelial cells: 59.9;Suprabasal keratinocytes: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 30.2;SK-BR-3: 26.7;T-47d: 28.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA055214 Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center" "HPA055214: AB_2682741" "unprognostic (3.12e-1)" "unprognostic (2.96e-1)" "unprognostic (1.26e-1)" "unprognostic (8.17e-2)" "unprognostic (5.51e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (2.61e-5)" "unprognostic (6.37e-2)" "unprognostic (2.44e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (4.31e-7)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (3.98e-2)" "unprognostic (2.37e-1)" 2.1 2.8 5.5 1.5 6.3 2.9 4.5 6.2 7.5 34.5 5.1 2.4 2.6 2.4 2.6 132.4 2.5 1.8 1.8 5.2 5.7 2.4 3.6 1.9 2.9 6.2 6.2 2.4 2.1 6.0 3.7 1.6 6.0 28.4 1.3 1.7 23.5 2.6 2.9 89.9 2.7 1.2 5.8 3.8 2.9 2.0 6.1 3.6 2.2 0.7 10.9 6.9 59.4 7.8 12.5 7.2 2.4 4.7 1.8 1.8 5.9 3.5 1.4 6.2 2.4 8.5 3.4 2.2 7.6 0.9 2.2 10.8 2.8 5.1 2.7 8.3 3.9 2.3 3.3 2.5 3.3 2.6 3.3 1.7 30.2 4.6 4.7 4.4 1.4 8.2 10.5 14.8 2.9 14.1 7.3 4.0 3.6 9.0 5.7 8.5 2.3 5.0 1.3 3.0 4.3 4.7 4.3 26.7 7.0 2.9 28.3 7.4 3.4 11.5 3.8 4.2 9.5 11.3 13.0 5.2 8.0 6.0 8.8 0.0 2.0 3.0 1.7 0.7 1.8 1.7 1.5 1.8 1.6 2.2 2.0 2.4 3.7 1.7 1.3 2.0 2.1 1.7 5.5 6.3 6.2 7.5 5.2 5.7 6.2 6.2 6.0 5.8 6.1 7.8 1.8 3.2 1.5 8.8 3.9 13.3 1.4 24.1 9.1 3.0 10.0 6.5 1.2 2.8 14.3 1.8 2.1 7.7 3.6 2.4 1.9 2.5 0.1 3.7 2.4 2.0 3.0 0.8 1.8 3.3 1.8 2.1 1.5 6.7 0.0 3.1 2.2 2.4 3.4 8.4 2.2 2.9 10.2 2.5 1.8 0.3 1.5 1.4 5.4 3.7 4.4 1.5 1.0 2.5 5.8 4.5 2.1 0.7 1.6 10.7 4.3 1.6 4.2 2.2 0.0 1.0 1.9 1.3 2.1 59.9 33.1 7.4 3.2 2.9 3.1 6.4 TMEM80 FLJ38216 ENSG00000177042 "Transmembrane protein 80" Q96HE8 11 695428-705028 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 82.2;Spermatogonia: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059592, HPA067046" Uncertain Approved "Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Golgi apparatus" "HPA059592: AB_2684076, HPA067046: AB_2685769" "unprognostic (1.48e-1)" "unprognostic (6.55e-3)" "unprognostic (1.70e-2)" "unprognostic (2.64e-2)" "unprognostic (2.71e-3)" "unprognostic (1.68e-3)" "unprognostic (4.36e-2)" "unprognostic (5.39e-3)" "unprognostic (3.85e-2)" "unprognostic (2.04e-1)" "unprognostic (1.41e-3)" "unprognostic (1.03e-1)" "prognostic favorable (2.47e-4)" "unprognostic (1.51e-1)" "unprognostic (2.78e-1)" "unprognostic (3.27e-1)" "unprognostic (4.23e-3)" 21.0 23.0 18.4 14.7 18.2 6.5 23.8 19.5 22.0 30.5 17.3 30.2 23.7 27.8 24.8 42.5 30.1 8.4 15.3 19.3 16.5 36.0 20.2 17.5 21.2 21.2 18.1 29.7 29.7 17.8 34.3 8.7 19.0 29.9 17.5 9.1 31.5 19.4 19.7 31.0 31.1 12.7 18.9 34.3 30.8 24.8 19.0 19.7 47.6 11.8 21.3 27.8 30.6 19.9 37.8 17.5 11.0 14.3 23.6 11.1 19.0 8.5 4.7 8.9 9.6 23.9 42.0 16.0 7.3 13.2 15.8 26.8 16.2 9.7 6.3 11.0 41.7 9.7 19.0 14.5 13.9 12.8 16.8 25.7 19.9 4.0 6.2 17.5 10.5 18.9 12.1 17.7 11.4 12.2 16.8 8.7 10.4 29.9 8.4 12.2 7.6 31.5 12.7 5.7 31.1 9.8 12.8 23.5 12.3 7.3 18.2 11.9 15.0 14.9 7.8 3.4 6.4 8.4 3.2 14.8 15.6 15.9 6.5 8.3 26.5 35.4 21.0 25.9 18.4 26.7 15.7 16.0 21.8 30.1 22.3 20.0 12.8 21.4 32.0 22.0 21.4 20.7 18.4 18.2 19.5 22.0 19.3 16.5 21.2 18.1 19.0 18.9 19.0 19.9 15.1 6.4 20.7 13.7 24.0 15.3 15.9 25.6 17.6 22.7 31.7 36.8 19.3 15.7 20.2 20.2 8.4 33.9 19.4 15.4 11.7 13.0 9.2 17.1 15.8 14.4 12.1 8.6 13.9 17.1 9.8 20.8 9.7 19.9 7.0 15.9 12.8 6.2 17.6 55.5 13.1 22.7 28.5 13.2 13.6 9.5 42.6 12.7 12.4 11.2 19.7 23.2 26.8 16.6 16.7 10.6 10.3 28.6 11.5 12.3 22.1 8.1 19.4 9.1 32.9 23.4 21.2 82.2 87.2 13.7 17.2 15.2 16.7 21.6 19.5 12.3 TMEM87A DKFZP564G2022 ENSG00000103978 "Transmembrane protein 87A" Q8NBN3 15 42210447-42273584 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 264.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018104, HPA018189" Enhanced Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus" "HPA018104: AB_1858135, HPA018189: AB_2205198" "unprognostic (7.07e-2)" "unprognostic (1.62e-2)" "unprognostic (2.19e-1)" "unprognostic (4.05e-2)" "unprognostic (2.49e-1)" "unprognostic (6.39e-3)" "unprognostic (1.19e-2)" "unprognostic (2.44e-1)" "unprognostic (2.95e-1)" "unprognostic (8.13e-3)" "unprognostic (4.31e-3)" "unprognostic (1.38e-1)" "unprognostic (3.41e-2)" "unprognostic (7.90e-2)" "unprognostic (2.19e-1)" "unprognostic (5.49e-3)" "unprognostic (3.63e-1)" 31.8 26.3 23.7 26.1 37.7 88.2 97.7 32.0 29.5 40.2 17.7 56.5 26.6 38.6 49.3 48.2 45.3 32.4 19.7 23.5 26.3 27.1 24.5 72.8 25.4 36.7 29.4 35.4 34.9 47.9 14.2 42.7 38.7 79.8 60.9 26.1 64.7 36.6 24.9 50.2 26.9 38.0 32.5 23.1 38.6 33.0 28.8 24.8 75.9 22.2 30.9 42.0 34.3 59.1 41.0 20.5 30.5 27.0 58.5 50.3 47.7 55.1 82.0 53.5 52.0 29.8 87.5 17.4 52.9 59.9 60.5 104.0 28.3 51.2 42.8 46.8 25.0 35.6 51.5 33.5 63.4 65.6 48.3 52.3 112.1 39.5 65.3 50.6 41.9 30.1 39.4 67.4 51.7 26.3 21.3 38.8 25.7 60.8 29.3 33.5 46.6 36.8 34.5 127.4 33.7 41.2 53.1 70.1 49.9 24.0 27.4 62.4 41.3 104.4 25.5 68.1 82.6 46.8 95.0 36.5 40.1 47.9 66.8 58.3 26.9 31.2 29.0 32.3 33.3 27.6 35.6 34.0 24.4 24.4 33.6 33.5 15.2 42.4 34.7 22.4 42.2 26.0 23.7 37.7 32.0 29.5 23.5 26.3 36.7 29.4 38.7 32.5 28.8 59.1 66.2 125.0 264.0 46.0 48.9 68.6 90.2 78.8 58.1 31.2 148.7 105.9 13.9 45.8 98.0 49.7 50.1 78.1 57.5 77.7 1.9 63.7 5.6 57.0 67.0 54.6 32.2 34.5 41.7 64.2 72.7 64.0 50.0 124.7 59.5 42.9 51.0 34.4 41.6 20.2 48.2 74.1 67.1 39.2 37.0 7.9 41.0 41.3 62.2 45.0 60.1 61.8 52.5 74.4 177.5 56.1 62.4 53.8 47.6 118.5 36.6 15.5 86.4 63.0 85.5 77.0 59.0 59.4 61.4 79.1 65.5 110.4 54.8 53.3 76.9 105.6 TMEM94 KIAA0195 ENSG00000177728 "Transmembrane protein 94" Q12767 17 75441159-75500452 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 43.0;Granulosa cells: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008423, HPA050660" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nuclear bodies" "HPA008423: AB_1852283, HPA050660: AB_2681207" "unprognostic (4.05e-2)" "unprognostic (3.43e-1)" "unprognostic (5.78e-2)" "unprognostic (4.32e-2)" "unprognostic (1.01e-1)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (1.70e-1)" "unprognostic (1.42e-1)" "unprognostic (7.27e-2)" "prognostic favorable (2.26e-4)" "unprognostic (9.71e-2)" "unprognostic (1.14e-1)" "unprognostic (1.21e-2)" "unprognostic (3.33e-1)" "unprognostic (1.44e-2)" "unprognostic (4.96e-2)" 21.3 55.9 50.3 13.9 46.4 18.4 21.7 27.7 54.9 21.9 30.5 25.1 18.8 24.4 5.4 21.1 30.7 15.8 27.8 40.7 31.5 29.7 20.2 25.6 14.1 40.1 36.8 27.7 23.7 20.3 30.1 14.2 30.5 19.9 13.6 27.7 21.1 13.2 63.4 22.9 28.2 10.7 34.8 29.7 25.0 27.1 47.1 18.0 27.4 25.8 8.6 20.5 15.3 35.8 15.3 40.7 33.6 52.6 16.1 18.8 45.6 9.2 20.0 15.4 15.4 13.7 22.6 20.6 30.3 15.9 23.6 19.9 15.8 25.6 8.8 19.4 23.1 22.0 18.4 22.9 21.2 23.7 45.2 30.9 14.5 15.0 13.4 13.9 28.1 18.3 22.6 24.4 20.7 19.1 53.3 18.8 14.4 19.3 16.2 36.2 37.2 19.2 16.0 40.7 28.1 30.5 10.2 47.4 28.7 25.3 29.8 29.3 16.0 16.5 19.0 16.5 13.8 53.2 17.2 12.2 17.2 23.8 20.8 0.1 2.6 3.0 3.5 1.6 2.6 1.0 1.6 2.5 2.5 2.5 1.3 2.2 0.7 2.4 1.4 3.3 2.1 2.9 50.3 46.4 27.7 54.9 40.7 31.5 40.1 36.8 30.5 34.8 47.1 35.8 12.8 12.8 11.1 0.0 5.8 0.0 3.3 0.0 6.2 43.0 10.9 9.1 0.0 12.8 6.2 9.2 31.3 16.1 8.8 18.0 0.0 8.1 4.7 10.1 6.8 8.2 7.3 10.7 0.0 9.5 11.0 4.4 28.1 8.6 6.3 41.5 13.9 8.9 15.4 20.2 0.0 10.5 0.0 12.4 0.0 1.9 6.8 8.9 0.0 0.0 5.6 15.2 4.1 0.0 0.0 6.0 9.1 9.1 8.1 3.3 19.6 3.4 2.9 33.6 6.6 7.5 6.0 14.9 8.8 9.7 0.0 20.1 6.9 19.0 9.3 3.1 TMEM95 "MGC129793, UNQ9390" ENSG00000182896 "Transmembrane protein 95" Q3KNT9 17 7355123-7357219 "Predicted intracellular proteins, Predicted membrane proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "testis: 11.1" "Group enriched" "Detected in some" 30 "Early spermatids: 43.3;Late spermatids: 36.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Intracellular and membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (1.15e-1)" "unprognostic (5.15e-2)" "unprognostic (7.42e-2)" "unprognostic (7.44e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 36.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.7 0.5 1.3 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 TMIE DFNB6 ENSG00000181585 "Transmembrane inner ear" Q8NEW7 3 46694528-46710886 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.6;choroid plexus: 10.5;pituitary gland: 9.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.8;Spermatocytes: 2.6;Spermatogonia: 3.2" "Cancer enriched" "Detected in many" 5 "glioma: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.4" "Lineage enriched" "Detected in single" 15 "T-cells: 2.4" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.1;EFO-21: 2.7;JURKAT: 10.7;SH-SY5Y: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038298 Uncertain Uncertain Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cytosol" "HPA038298: AB_10675792" "unprognostic (6.59e-2)" "unprognostic (1.11e-1)" "unprognostic (7.25e-3)" "unprognostic (2.48e-3)" "unprognostic (1.88e-2)" "unprognostic (5.40e-3)" "unprognostic (3.94e-2)" "unprognostic (8.80e-2)" "unprognostic (3.37e-2)" "unprognostic (6.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.35e-2)" "unprognostic (4.58e-2)" "unprognostic (1.23e-1)" "unprognostic (4.41e-2)" "unprognostic (5.29e-2)" "unprognostic (6.78e-2)" 0.7 6.2 14.2 0.5 14.1 0.0 0.4 14.0 18.0 0.7 10.5 1.0 0.4 0.5 0.7 1.5 0.6 0.2 0.7 14.1 19.3 2.3 0.8 1.0 0.8 19.6 15.7 1.5 0.2 0.1 9.9 0.4 19.2 0.5 0.3 0.7 0.5 1.0 3.6 0.7 0.5 0.4 16.0 0.7 0.3 1.5 18.7 0.5 0.9 1.2 0.8 0.6 0.9 14.9 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.1 0.0 2.7 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.0 0.0 1.8 0.0 1.2 0.0 0.5 10.7 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.7 0.1 1.2 0.0 0.3 0.1 0.1 0.3 2.3 0.3 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.1 0.0 2.4 0.4 0.0 0.0 0.0 0.0 0.4 0.4 14.2 14.1 14.0 18.0 14.1 19.3 19.6 15.7 19.2 16.0 18.7 14.9 1.9 0.0 0.0 0.3 0.0 0.8 0.2 0.5 0.0 3.8 0.2 0.6 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.9 0.4 0.5 0.2 0.0 0.7 0.0 0.0 1.7 0.4 0.1 0.4 0.0 0.1 0.0 0.1 0.4 0.1 0.6 0.0 0.8 0.0 0.0 0.0 0.4 1.5 0.6 0.3 0.0 1.9 0.1 1.4 0.0 0.0 0.3 1.2 0.0 0.4 0.0 0.3 0.0 0.0 0.6 0.5 0.0 1.1 1.0 2.6 3.2 0.0 0.9 0.1 0.2 0.1 0.0 0.2 TMIGD1 "TMIGD, UNQ9372" ENSG00000182271 "Transmembrane and immunoglobulin domain containing 1" Q6UXZ0 17 30316333-30334059 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "intestine: 140.5" "Group enriched" "Detected in some" 28 "Distal enterocytes: 291.9;Paneth cells: 125.5;Proximal enterocytes: 476.6" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021946 Approved Mitochondria NA NA "Cluster 9: Intestine - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA021946: AB_1858140" "unprognostic (1.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.5 0.0 0.0 0.0 0.0 0.0 140.5 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 291.9 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 125.5 0.0 0.0 0.0 476.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.5 0.0 TMIGD2 "CD28H, IGPR-1, MGC23244" ENSG00000167664 "Transmembrane and immunoglobulin domain containing 2" Q96BF3 19 4292232-4302431 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 35.3" "Group enriched" "Detected in some" 4 "dendritic cells: 49.9;NK-cells: 104.0;T-cells: 45.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 114.3" "Group enriched" "Detected in many" 38 "dendritic cells: 109.4;NK-cells: 89.8;T-cells: 114.3" "Group enriched" "Detected in some" 4 "BEWO: 12.4;HEL: 30.0;MOLT-4: 27.2" "Low region specificity" "Detected in single" HPA011081 Approved NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA011081: AB_1079372" "unprognostic (1.08e-3)" "unprognostic (6.55e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-4)" "unprognostic (4.31e-2)" "unprognostic (8.68e-3)" "unprognostic (7.78e-3)" "unprognostic (2.87e-2)" "unprognostic (1.86e-1)" "unprognostic (2.28e-1)" "unprognostic (2.12e-1)" "unprognostic (3.26e-1)" "unprognostic (7.10e-5)" "unprognostic (2.62e-2)" "unprognostic (4.54e-1)" "unprognostic (5.12e-4)" "unprognostic (8.89e-4)" 0.3 0.2 1.5 4.2 1.5 4.8 0.2 1.4 1.7 0.2 0.7 1.4 1.4 0.5 0.0 0.5 0.4 0.7 0.1 1.5 1.8 0.2 0.8 0.9 6.4 1.9 1.7 0.0 0.1 0.0 0.1 0.4 1.7 0.3 0.5 0.1 0.2 0.1 0.1 0.1 4.1 0.1 1.5 6.4 0.7 0.6 1.8 35.3 0.2 0.1 3.4 0.6 0.3 1.7 0.0 0.1 0.3 0.3 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 30.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 27.2 0.0 0.1 0.0 0.0 5.2 1.4 0.0 0.0 0.2 0.1 3.3 0.0 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.2 0.8 9.0 0.1 114.3 0.2 15.0 22.5 0.4 0.3 82.9 43.2 2.7 89.8 0.5 109.4 1.3 23.3 1.5 1.5 1.4 1.7 1.5 1.8 1.9 1.7 1.7 1.5 1.8 1.7 0.3 0.0 0.6 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.2 1.5 0.0 0.0 0.0 1.8 49.9 0.1 0.0 0.1 0.0 0.2 0.3 0.2 0.0 14.9 0.2 0.0 0.5 1.2 7.1 0.2 1.3 0.4 1.4 0.6 0.3 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 1.7 1.8 3.7 1.6 0.0 104.0 0.0 0.1 0.0 0.0 0.4 3.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.0 0.0 0.1 0.8 45.4 0.0 0.0 0.2 TMPPE FLJ45032 ENSG00000188167 "Transmembrane protein with metallophosphoesterase domain" Q6ZT21 3 33090421-33097146 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.5" "Cell type enhanced" "Detected in some" "Rod photoreceptor cells: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "BEWO: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027019 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Mitochondria" "HPA027019: AB_1848942" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (1.00e-1)" "unprognostic (1.37e-1)" "unprognostic (5.03e-2)" "unprognostic (2.96e-2)" "unprognostic (6.34e-3)" "unprognostic (8.14e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "unprognostic (1.25e-3)" "unprognostic (9.58e-2)" "unprognostic (1.60e-7)" "unprognostic (1.61e-1)" "unprognostic (5.40e-2)" "unprognostic (2.13e-1)" "unprognostic (4.33e-2)" 0.6 0.5 0.8 1.4 0.7 5.5 0.6 0.7 1.2 0.6 4.3 1.0 1.2 0.5 0.6 0.6 0.9 0.6 0.4 1.5 0.5 1.0 0.6 1.1 1.1 1.4 1.4 0.6 0.7 1.9 0.3 1.2 1.6 0.5 1.2 2.8 0.7 0.6 0.2 1.1 1.1 0.8 0.2 1.5 1.3 0.3 1.7 0.5 1.0 0.3 1.3 0.8 0.4 0.2 1.4 1.9 1.0 1.7 1.2 1.0 27.2 0.6 1.0 1.6 0.9 2.7 3.8 0.8 1.2 1.7 0.9 1.4 1.7 1.5 2.6 4.2 0.6 3.4 1.9 2.1 0.9 3.0 4.7 1.1 1.2 2.0 1.4 0.8 1.9 1.7 2.6 2.9 1.2 1.3 1.2 1.3 1.0 0.4 1.1 1.5 0.6 1.9 1.5 1.9 0.2 0.6 0.9 2.6 0.6 1.3 1.4 4.2 2.7 2.4 3.0 1.3 2.6 2.3 1.6 0.4 3.0 2.2 1.7 0.0 1.1 0.3 0.1 2.4 0.6 0.3 0.2 0.0 1.0 0.1 0.0 0.0 1.9 0.0 1.1 0.2 0.2 0.4 0.8 0.7 0.7 1.2 1.5 0.5 1.4 1.4 1.6 0.2 1.7 0.2 0.3 0.0 1.3 0.0 0.8 0.8 0.1 0.0 0.0 1.2 0.4 0.4 0.4 0.0 0.2 0.0 0.0 1.1 1.9 1.4 0.0 0.4 0.0 0.8 0.6 0.4 0.0 0.4 0.0 0.8 1.7 0.3 0.0 1.1 0.0 0.4 0.4 0.6 0.9 1.7 0.0 0.2 2.0 1.3 1.2 0.0 0.0 1.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.5 1.4 0.4 1.0 0.2 1.4 0.3 0.4 2.2 0.0 0.2 0.7 0.0 0.0 1.5 0.9 0.4 0.6 0.5 0.6 0.2 TMPRSS12 "CT151, MGC57341" ENSG00000186452 "Transmembrane serine protease 12" Q86WS5 12 50842920-50887884 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 50 "testis: 21.6" "Group enriched" "Detected in some" 8 "Early spermatids: 44.7;Spermatocytes: 121.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.04e-1)" "unprognostic (9.09e-2)" "unprognostic (3.03e-2)" "unprognostic (7.25e-3)" "unprognostic (1.70e-1)" "unprognostic (1.39e-1)" "unprognostic (3.88e-1)" "unprognostic (2.98e-2)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "unprognostic (5.65e-3)" "unprognostic (1.03e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.2 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 21.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.7 0.0 0.3 0.5 0.2 0.0 0.0 0.8 0.5 0.1 0.0 0.1 1.8 0.0 0.9 0.1 0.0 0.0 0.0 44.7 0.1 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 9.7 4.1 0.1 1.8 0.0 0.0 0.0 0.0 2.0 0.6 0.0 0.0 0.7 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 121.7 2.4 0.0 0.3 0.7 0.0 0.0 0.0 0.1 TMPRSS15 "ENTK, MGC133046, PRSS7" ENSG00000154646 "Transmembrane serine protease 15" P98073 21 18269116-18485879 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 512 "intestine: 979.8" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 28.0" "Group enriched" "Detected in some" 12 "liver cancer: 0.7;pancreatic cancer: 1.5;stomach cancer: 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "U-138 MG: 50.8;U-87 MG: 141.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "olfactory bulb: 5.0;spinal cord: 1.8" "HPA015611, HPA034857, HPA072934" Enhanced Approved "Plasma membrane" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA015611: AB_1855791, HPA034857: , HPA072934: AB_2732214" "unprognostic (9.26e-2)" "unprognostic (4.14e-1)" "unprognostic (3.52e-1)" "unprognostic (8.33e-2)" "unprognostic (1.19e-1)" "unprognostic (7.20e-2)" "unprognostic (4.70e-2)" "unprognostic (6.35e-2)" "unprognostic (5.92e-2)" 0.0 0.0 0.9 0.2 0.7 0.0 0.0 1.9 1.7 0.0 0.0 0.2 979.8 0.2 0.0 0.1 0.0 0.1 0.1 0.7 0.6 0.0 0.0 0.0 0.7 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 21.8 0.0 0.0 0.0 0.4 1.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.3 0.0 4.6 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.8 0.0 0.3 0.0 0.9 0.0 0.2 141.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.7 1.9 1.7 0.7 0.6 0.2 0.6 0.1 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 4.0 0.0 TMPRSS5 "MGC141886, MGC148044" ENSG00000166682 "Transmembrane serine protease 5" Q9H3S3 11 113687547-113706373 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.6;choroid plexus: 20.8" "Cell type enhanced" "Detected in some" "Astrocytes: 26.4;Excitatory neurons: 5.4;Horizontal cells: 5.0;Oligodendrocytes: 15.5" "Cancer enhanced" "Detected in some" "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.0;CAPAN-2: 3.2;OE19: 2.0;WM-115: 2.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010992 Approved Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA010992: AB_1858152" "unprognostic (1.53e-2)" "unprognostic (3.81e-2)" "unprognostic (2.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (2.99e-3)" "unprognostic (3.08e-1)" "unprognostic (5.19e-3)" "unprognostic (8.49e-2)" "unprognostic (8.13e-2)" "unprognostic (3.38e-2)" "unprognostic (1.96e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "unprognostic (4.04e-3)" 1.3 0.5 28.1 0.2 34.7 1.4 2.0 24.9 39.0 0.8 20.8 0.7 0.1 0.5 0.2 0.5 0.7 0.7 1.0 28.2 27.0 1.0 1.0 0.7 0.2 34.0 29.8 0.6 0.5 0.0 1.6 0.2 33.1 0.8 0.3 1.1 9.6 0.3 2.6 2.1 0.7 0.3 28.5 0.8 0.8 2.1 32.1 0.3 0.6 0.5 0.3 0.7 1.0 50.6 0.2 0.3 2.0 1.1 0.2 0.1 0.3 0.5 0.2 0.3 0.4 1.1 3.2 0.1 1.4 0.2 0.3 0.4 0.1 0.2 0.1 0.2 0.6 0.4 0.3 0.0 0.1 0.5 0.4 0.2 0.2 0.2 0.5 0.2 0.3 0.7 0.4 0.2 0.4 0.0 0.4 0.6 0.2 2.0 0.1 0.4 0.2 0.0 0.3 0.2 0.3 0.4 0.2 0.0 1.6 0.2 0.2 0.2 0.2 0.4 0.7 0.3 0.3 0.2 0.1 0.0 0.1 0.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 34.7 24.9 39.0 28.2 27.0 34.0 29.8 33.1 28.5 32.1 50.6 0.2 0.0 0.0 26.4 0.2 0.3 0.2 0.0 0.0 0.5 1.0 0.9 0.5 0.0 0.1 1.8 2.1 0.0 0.2 0.2 0.0 0.3 0.1 0.3 0.2 0.3 0.0 1.3 5.4 0.9 0.0 0.3 0.0 0.4 0.0 0.4 0.4 0.2 0.1 5.0 2.8 0.0 0.0 0.0 0.3 0.3 0.3 0.1 0.0 2.8 0.1 3.2 0.0 3.5 15.5 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.1 1.3 0.0 0.5 0.1 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 TMTC4 "FLJ14624, FLJ22153" ENSG00000125247 "Transmembrane O-mannosyltransferase targeting cadherins 4" Q5T4D3 13 100603625-100675093 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 139.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016489, HPA057056" Approved Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA016489: AB_1858157, HPA057056: " "unprognostic (1.49e-1)" "unprognostic (1.87e-1)" "unprognostic (8.34e-2)" "unprognostic (1.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.96e-1)" "unprognostic (1.50e-2)" "unprognostic (1.96e-1)" "unprognostic (1.88e-2)" "unprognostic (1.09e-1)" "unprognostic (3.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.41e-1)" "unprognostic (1.99e-1)" "unprognostic (6.04e-2)" "unprognostic (9.18e-2)" "unprognostic (2.65e-2)" 5.2 4.2 13.4 5.9 22.9 3.1 6.5 18.9 34.0 6.9 11.5 8.4 9.9 9.6 8.0 5.1 14.3 5.7 4.0 14.0 16.0 12.5 11.3 4.3 4.8 21.6 19.4 6.1 10.5 10.7 3.3 5.0 21.9 8.7 8.5 10.0 8.7 6.0 13.6 7.4 8.6 7.0 17.9 4.3 9.2 11.8 19.1 7.1 8.1 8.7 5.7 7.7 4.6 32.2 10.4 7.7 42.2 21.2 5.7 10.5 44.6 5.5 5.0 5.0 4.1 8.1 17.5 29.6 18.4 5.0 12.0 6.8 13.5 7.8 6.6 16.9 9.3 12.6 15.4 13.0 7.1 15.7 0.4 14.7 11.1 2.2 8.8 14.8 23.5 16.1 9.5 3.7 5.7 9.2 12.5 9.0 11.3 27.8 7.8 13.9 7.7 6.8 19.8 7.4 21.1 21.9 11.1 19.7 5.3 26.0 14.6 44.6 36.6 4.8 8.2 4.1 9.7 9.5 9.1 5.8 22.4 9.9 13.5 0.0 1.1 0.1 1.3 1.2 1.1 1.0 1.3 2.1 3.3 1.2 1.5 0.5 0.0 0.7 1.8 2.3 2.1 0.8 13.4 22.9 18.9 34.0 14.0 16.0 21.6 19.4 21.9 17.9 19.1 32.2 4.7 6.4 3.9 18.9 4.5 3.1 7.2 4.2 3.4 19.0 10.7 4.1 11.3 18.6 6.2 5.5 8.4 11.6 5.6 7.7 1.9 11.6 5.8 12.2 9.7 8.4 10.7 5.0 11.1 18.7 19.8 6.2 6.1 14.4 0.0 12.8 39.7 15.3 4.3 26.9 19.4 10.1 2.0 6.9 2.5 6.2 4.1 3.7 3.6 9.4 3.3 8.2 5.2 15.1 139.6 13.0 7.4 6.8 3.6 10.9 10.5 14.2 6.8 8.6 6.6 4.2 5.8 9.7 32.3 7.9 5.8 3.1 4.1 5.3 11.7 5.3 TMUB1 "C7orf21, HOPS, SB144" ENSG00000164897 "Transmembrane and ubiquitin like domain containing 1" Q9BVT8 7 151081085-151083493 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 191.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029429 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA029429: AB_10601825" "unprognostic (8.14e-2)" "unprognostic (2.19e-2)" "unprognostic (2.76e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-3)" "unprognostic (7.04e-2)" "unprognostic (2.12e-3)" "unprognostic (7.73e-2)" "unprognostic (1.25e-1)" "unprognostic (2.93e-2)" "unprognostic (1.74e-2)" "unprognostic (2.24e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-3)" "unprognostic (2.74e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" 33.1 53.3 26.8 25.6 24.7 23.0 34.3 25.6 38.6 34.0 19.4 52.7 47.2 33.6 8.6 54.2 32.8 14.9 50.4 24.9 24.6 56.3 131.3 41.6 26.3 29.6 25.9 37.0 93.5 20.3 68.8 20.4 27.0 51.2 8.3 5.2 44.1 14.9 84.5 47.0 56.7 9.0 24.2 53.6 66.8 25.9 29.4 17.9 51.3 20.0 12.1 40.8 38.9 23.7 88.3 77.5 18.0 93.2 11.6 14.2 67.2 35.3 29.3 30.8 34.3 67.5 104.6 58.6 73.9 17.4 39.9 58.6 20.0 31.2 6.8 108.0 74.4 24.8 74.8 104.7 29.5 31.3 84.8 22.0 25.4 25.8 6.9 23.4 22.9 59.3 159.4 77.4 14.0 141.2 104.5 134.5 77.2 51.7 48.3 64.8 22.7 108.5 32.2 67.4 65.6 73.2 28.6 43.6 47.9 10.6 34.0 42.9 28.3 39.0 28.5 49.3 59.1 121.2 72.5 41.4 89.8 58.2 50.4 4.2 3.1 23.8 5.7 4.3 5.0 5.3 8.7 6.4 3.2 11.2 8.7 4.8 5.3 3.7 2.6 4.8 12.1 2.4 26.8 24.7 25.6 38.6 24.9 24.6 29.6 25.9 27.0 24.2 29.4 23.7 24.0 6.4 3.2 7.5 51.2 26.4 25.9 26.0 31.9 15.2 45.7 34.8 9.9 28.6 15.9 22.0 14.6 93.1 50.2 136.7 35.2 73.1 11.9 15.8 11.7 21.5 41.3 23.2 4.5 109.6 60.2 18.3 52.0 29.3 15.9 23.3 25.4 51.4 44.2 20.2 5.3 85.9 46.8 30.4 61.2 5.1 12.5 32.4 32.0 6.5 44.8 28.9 70.0 2.5 7.2 96.3 109.7 16.6 67.8 39.3 191.0 37.9 6.4 16.0 39.5 9.3 21.8 22.3 15.6 39.5 36.9 94.5 52.8 25.4 84.0 37.9 TMUB2 MGC3123 ENSG00000168591 "Transmembrane and ubiquitin like domain containing 2" Q71RG4 17 44186970-44191929 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043137 Approved Approved Vesicles,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Vesicles, Cytosol" "HPA043137: AB_10794388" "unprognostic (4.57e-2)" "unprognostic (1.58e-2)" "unprognostic (6.06e-2)" "unprognostic (1.26e-2)" "unprognostic (6.37e-2)" "unprognostic (1.85e-2)" "unprognostic (6.43e-3)" "unprognostic (1.07e-1)" "unprognostic (2.05e-1)" "unprognostic (3.35e-2)" "unprognostic (1.80e-1)" "unprognostic (1.58e-1)" "unprognostic (2.12e-1)" "unprognostic (9.75e-3)" "unprognostic (3.67e-2)" "unprognostic (2.12e-1)" "unprognostic (2.78e-3)" 32.2 35.7 34.1 22.9 34.4 43.9 32.5 34.9 38.1 37.3 32.5 39.1 24.5 32.5 21.9 37.3 33.9 25.2 33.1 34.2 32.8 36.9 35.8 31.5 26.3 33.6 33.8 35.2 36.9 27.5 32.9 25.9 32.9 42.0 21.9 16.8 36.1 26.3 32.7 32.4 36.5 21.7 32.2 52.8 36.7 46.8 34.2 23.2 42.7 20.0 20.5 35.3 34.3 34.3 22.8 43.0 27.6 25.1 41.6 32.8 21.6 29.5 31.6 53.7 54.4 22.7 41.5 15.8 31.1 36.1 40.5 42.3 19.3 28.0 33.4 38.7 39.7 16.5 40.9 35.1 43.8 18.7 35.5 40.1 39.8 36.9 22.9 45.1 37.8 25.8 19.2 45.4 35.7 15.9 26.0 23.8 9.1 19.0 35.7 23.2 33.3 25.5 33.8 25.2 21.8 22.2 15.5 14.4 29.4 27.6 42.2 23.0 31.8 44.4 27.0 31.1 26.7 33.5 26.1 15.4 34.0 15.7 30.4 84.1 30.0 57.3 17.1 26.7 14.5 16.6 14.3 16.5 19.1 23.8 13.4 15.3 65.4 13.9 29.0 23.1 18.1 20.4 34.1 34.4 34.9 38.1 34.2 32.8 33.6 33.8 32.9 32.2 34.2 34.3 24.8 35.3 25.9 21.2 40.8 13.0 21.2 27.0 25.6 30.8 29.8 25.3 16.7 22.8 27.2 22.0 31.3 46.3 24.9 42.5 3.9 21.0 51.0 13.9 16.8 20.4 33.5 25.7 15.8 18.8 29.6 22.0 23.0 25.1 22.1 25.6 18.9 13.9 42.6 21.9 16.4 27.1 12.2 37.9 25.9 28.4 21.8 30.9 14.2 16.9 31.5 29.1 25.7 14.6 12.2 25.8 33.2 24.0 18.8 20.5 39.6 10.7 18.9 27.9 26.3 14.6 19.6 81.5 37.1 17.2 14.9 96.7 27.6 30.0 27.0 23.4 TMX2 "PDIA12, TXNDC14" ENSG00000213593 "Thioredoxin related transmembrane protein 2" Q9Y320 11 57712593-57740973 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Lissencephaly, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040282, HPA063763" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "HPA040282: AB_10697715, HPA063763: AB_2685116" "unprognostic (3.66e-3)" "unprognostic (6.96e-2)" "unprognostic (6.69e-3)" "unprognostic (2.73e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.64e-4)" "prognostic unfavorable (4.11e-4)" "unprognostic (4.48e-2)" "unprognostic (2.98e-1)" "unprognostic (7.26e-3)" "unprognostic (1.90e-2)" "unprognostic (2.22e-1)" "prognostic favorable (1.55e-5)" "unprognostic (5.88e-3)" "unprognostic (4.19e-2)" "unprognostic (3.40e-1)" "prognostic unfavorable (3.37e-4)" 52.9 75.1 77.7 37.3 83.0 27.0 50.5 87.4 101.9 43.6 103.3 70.0 56.4 39.4 58.2 62.8 42.7 33.2 71.5 75.0 84.1 78.7 83.4 45.0 31.5 81.7 81.5 40.9 57.7 84.9 43.1 44.0 83.5 50.1 80.8 64.7 49.6 53.8 44.7 45.1 58.3 43.1 84.3 44.9 60.9 30.6 85.5 34.9 57.1 41.3 47.6 48.2 43.8 90.6 122.7 141.4 78.5 143.4 144.8 77.2 86.6 144.2 111.8 140.0 117.9 135.3 205.6 115.1 156.6 116.3 207.1 220.0 203.5 115.4 146.3 83.3 88.9 110.2 105.7 136.8 119.3 156.6 145.5 94.8 166.5 154.8 243.2 76.3 80.6 95.3 194.4 130.9 157.7 62.7 93.0 177.1 153.8 227.7 191.5 124.7 97.9 242.5 174.4 136.4 90.3 129.3 110.2 255.7 168.3 76.7 228.5 102.2 66.7 130.5 84.8 176.1 152.1 127.9 269.5 115.3 146.6 109.3 198.3 37.8 41.5 40.0 34.6 72.4 44.0 36.8 34.4 40.9 40.6 34.9 43.1 43.8 11.2 37.8 86.0 49.7 32.0 45.0 77.7 83.0 87.4 101.9 75.0 84.1 81.7 81.5 83.5 84.3 85.5 90.6 37.9 38.5 34.0 0.0 32.0 32.1 44.9 108.2 19.9 43.4 35.8 28.1 42.6 30.0 60.8 49.7 31.3 108.0 29.9 39.5 43.0 72.4 2.0 19.6 27.4 36.8 28.8 37.6 0.0 43.5 85.6 38.6 23.0 20.7 43.1 29.9 31.8 48.7 62.0 30.3 0.0 49.6 81.4 30.8 21.4 3.6 48.7 31.9 48.0 0.0 37.8 91.1 19.6 0.0 0.0 54.5 32.0 43.6 32.5 49.0 51.4 41.1 37.4 66.7 39.5 36.3 34.5 60.7 62.2 33.6 32.7 99.6 26.6 46.6 75.2 43.6 TMX3 "FLJ20793, KIAA1830, PDIA13, TXNDC10" ENSG00000166479 "Thioredoxin related transmembrane protein 3" Q96JJ7 18 68673688-68715108 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014157 Uncertain "Intracellular and membrane" NA NA 36000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA014157: AB_1858469" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.14e-2)" "unprognostic (9.47e-2)" "unprognostic (6.82e-2)" "unprognostic (7.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (5.20e-2)" "unprognostic (9.83e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.69e-2)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" 22.7 16.2 11.7 24.1 13.0 14.1 19.2 14.2 15.4 15.0 9.9 12.7 18.2 16.6 20.4 14.1 13.8 16.5 20.8 13.5 13.2 14.6 16.2 19.5 27.9 11.1 11.2 13.0 11.9 15.9 9.6 19.8 12.1 17.7 16.3 26.0 10.6 13.0 11.0 16.7 18.8 21.0 11.4 22.6 14.0 11.4 12.1 23.3 17.7 21.0 22.7 20.1 11.2 11.5 11.1 17.4 32.9 25.9 66.6 70.7 24.5 85.7 91.0 61.0 67.7 8.4 31.9 31.4 16.6 125.4 25.9 40.8 21.9 42.9 92.8 30.3 19.6 28.8 27.4 14.7 70.6 62.0 45.7 56.5 27.1 66.2 59.2 61.8 78.4 27.0 18.9 42.5 73.1 6.9 33.3 19.6 13.9 9.1 28.2 30.7 65.5 38.5 51.7 24.2 31.5 24.5 42.0 26.7 31.8 32.4 17.6 52.1 76.4 108.4 30.0 24.7 63.6 28.4 30.4 29.4 65.5 50.1 81.3 2.2 2.9 2.4 3.8 4.7 5.5 3.1 3.9 3.6 4.7 2.1 4.3 4.4 0.7 4.9 3.3 6.4 4.4 2.7 11.7 13.0 14.2 15.4 13.5 13.2 11.1 11.2 12.1 11.4 12.1 11.5 31.4 28.9 27.8 36.2 25.0 20.3 17.2 17.6 12.0 29.1 21.0 15.6 25.1 10.0 18.8 16.5 18.8 15.0 44.3 10.6 1.9 15.2 8.9 18.7 38.5 27.3 18.0 17.0 77.9 10.2 20.8 34.5 13.3 25.6 20.3 24.2 34.2 26.6 18.6 26.9 45.6 13.8 14.2 23.3 26.8 3.3 24.2 23.9 24.9 32.8 18.2 20.5 20.6 49.8 53.1 15.4 15.4 16.6 29.8 19.4 17.5 8.0 28.8 32.5 39.5 23.6 32.0 23.8 28.3 21.7 24.3 12.4 23.3 22.9 9.4 16.6 TNC "DFNA56, HXB, MGC167029, TN" ENSG00000041982 "Tenascin C" P24821 9 115019575-115118257 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 376.2" "Cell type enhanced" "Detected in many" "Astrocytes: 160.3;Basal prostatic cells: 72.1;Basal respiratory cells: 150.6;Basal squamous epithelial cells: 126.3;Prostatic glandular cells: 69.2;Smooth muscle cells: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 798.5;hTEC/SVTERT24-B: 634.4;U-138 MG: 526.0;U-251 MG: 484.5;U-87 MG: 711.8;WM-115: 1253.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004592, HPA004823" Approved "Secreted to extracellular matrix" NA NA 560000000 840000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB004592: AB_628342, HPA004823: AB_1080243" "unprognostic (5.46e-2)" "unprognostic (3.76e-2)" "unprognostic (7.57e-2)" "unprognostic (1.69e-1)" "unprognostic (9.20e-2)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (7.86e-3)" "unprognostic (2.68e-3)" "unprognostic (1.59e-2)" "unprognostic (1.82e-1)" "unprognostic (4.87e-3)" "unprognostic (1.79e-2)" "unprognostic (1.92e-2)" "unprognostic (7.60e-2)" "unprognostic (1.97e-3)" 61.0 4.7 16.4 170.4 28.5 0.9 41.2 14.0 9.8 43.6 3.0 174.3 16.7 106.8 12.2 23.9 25.5 14.1 32.6 15.6 34.3 82.0 7.7 54.2 39.8 20.3 43.8 5.3 4.8 2.3 7.2 4.0 28.0 39.1 28.3 4.8 19.8 33.3 6.2 25.9 56.5 376.2 15.0 40.8 62.4 4.8 65.4 17.1 13.3 3.2 22.6 96.7 15.9 20.5 25.1 6.0 6.9 1.3 37.5 10.1 0.1 205.7 798.5 425.4 203.6 5.3 55.3 0.0 32.8 291.7 6.9 89.9 0.0 12.0 241.3 0.4 2.2 0.0 4.8 0.0 0.7 0.4 3.9 6.2 1.7 634.4 289.9 42.9 0.1 0.0 0.0 5.2 11.4 0.0 0.1 0.3 65.2 0.9 85.3 0.2 451.9 0.1 373.3 0.1 0.6 5.9 91.4 0.2 19.3 140.9 1.0 1.4 0.1 526.0 88.4 94.2 484.5 14.3 0.4 0.4 711.8 0.6 1253.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 16.4 28.5 14.0 9.8 15.6 34.3 20.3 43.8 28.0 15.0 65.4 20.5 0.7 12.8 43.5 160.3 0.4 12.1 72.1 150.6 126.3 0.1 9.3 33.3 1.4 0.0 14.8 1.8 0.0 1.1 0.3 0.0 0.0 25.8 15.4 6.7 47.8 11.1 0.0 0.0 7.0 4.5 0.6 19.0 0.0 24.9 2.5 0.5 6.1 0.0 1.2 0.0 0.9 0.0 0.0 0.6 4.7 18.4 3.4 0.9 5.4 1.9 0.1 1.3 0.0 4.0 0.8 3.9 0.0 0.4 0.3 69.2 0.0 0.3 3.5 0.2 0.0 1.3 58.9 0.4 0.2 4.8 4.5 1.0 2.6 0.1 0.1 5.8 TNF "DIF, TNF-alpha, TNFA, TNFSF2" ENSG00000232810 "Tumor necrosis factor" P01375 6 31575565-31578336 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.7;lymphoid tissue: 6.5" "Cell type enhanced" "Detected in many" "B-cells: 90.7;dendritic cells: 60.8;Langerhans cells: 72.7;Macrophages: 108.3;T-cells: 100.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 68.0" "Group enriched" "Detected in all" 5 "granulocytes: 20.8;monocytes: 68.0;T-cells: 36.6" "Group enriched" "Detected in some" 8 "HDLM-2: 103.7;NB-4: 214.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB078469 Supported "Secreted to blood" NA NA 10100 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "CAB078469: AB_908070" "unprognostic (1.93e-1)" "unprognostic (1.07e-2)" "unprognostic (3.85e-2)" "unprognostic (1.05e-1)" "unprognostic (1.92e-1)" "unprognostic (2.19e-2)" "unprognostic (1.67e-1)" "unprognostic (3.46e-1)" "unprognostic (1.19e-2)" "unprognostic (1.94e-1)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (1.46e-2)" "unprognostic (1.82e-1)" "unprognostic (9.85e-3)" "unprognostic (1.09e-1)" "unprognostic (2.04e-1)" 1.4 0.5 0.0 3.3 0.0 12.7 0.5 0.0 0.1 0.1 0.0 0.9 0.0 1.5 0.0 0.7 0.3 0.6 2.6 0.1 0.0 1.2 0.6 3.6 1.6 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 1.5 2.4 0.2 0.1 6.5 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.8 0.0 0.0 0.0 0.0 103.7 0.0 19.4 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 214.4 0.0 0.0 0.0 9.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 10.1 0.0 23.2 39.5 36.6 7.2 17.2 13.9 7.6 7.0 5.0 5.2 20.8 2.0 68.0 4.3 13.6 14.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.4 0.0 3.0 0.0 90.7 8.4 1.2 12.1 4.6 0.2 17.4 20.4 2.0 2.8 4.0 0.0 2.1 0.9 60.8 0.5 0.0 7.4 0.1 15.5 5.9 10.7 0.0 0.0 0.0 3.3 1.7 2.0 1.5 30.5 12.6 0.0 1.8 0.1 36.5 0.0 0.0 0.4 10.2 14.1 72.7 0.0 0.3 108.3 5.4 1.9 3.4 0.1 2.1 0.0 0.1 14.3 0.0 0.0 10.4 1.7 0.0 0.1 3.0 0.2 0.0 0.6 4.0 0.0 0.0 1.3 4.1 1.1 100.0 0.0 0.4 0.3 TNFRSF11A "CD265, FEO, LOH18CR1, PDB2, RANK" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.5;salivary gland: 25.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.6;Intestinal goblet cells: 24.0;Paneth cells: 42.3;Proximal enterocytes: 25.5;Undifferentiated cells: 42.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 5.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 5.3" "Cell line enriched" "Detected in many" 6 "HDLM-2: 125.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 110000 "Cluster 48: NK-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" 1.8 1.1 0.8 5.7 1.6 0.4 4.1 0.1 1.9 1.4 0.3 17.1 30.5 0.9 0.3 2.8 0.9 7.6 0.6 2.0 1.1 0.4 0.6 1.0 1.2 0.7 1.1 0.4 1.7 0.9 6.8 3.2 0.2 1.3 17.6 0.2 25.4 2.7 0.3 2.7 18.6 1.7 0.7 0.8 5.5 0.9 1.2 1.0 1.2 0.1 1.9 1.6 1.6 2.1 3.2 2.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.6 0.4 0.6 0.0 3.5 0.4 1.4 2.2 8.3 0.9 0.2 125.9 5.4 0.0 1.3 1.7 0.0 0.5 1.3 0.2 0.4 0.8 3.1 4.2 3.1 0.3 0.0 0.0 0.0 1.1 0.0 0.1 5.9 7.0 19.3 0.4 0.0 0.6 1.5 1.5 20.4 0.7 0.6 3.0 0.1 0.8 1.3 0.4 2.0 0.0 0.1 0.1 0.0 1.2 0.0 0.1 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.3 0.6 0.0 0.8 1.6 0.1 1.9 2.0 1.1 0.7 1.1 0.2 0.7 1.2 2.1 0.4 0.0 2.2 0.0 0.4 1.3 3.8 1.1 0.6 0.6 4.5 3.3 1.3 8.6 2.3 0.0 0.0 0.1 3.3 35.6 0.0 8.3 0.3 3.2 0.5 5.3 10.8 0.0 4.0 7.5 0.6 0.7 11.7 6.2 0.0 2.0 7.1 0.3 15.5 3.3 0.2 24.0 0.0 17.0 2.4 0.4 0.6 7.7 1.8 8.4 19.7 0.0 3.1 0.5 0.4 14.7 42.3 0.0 0.5 2.8 25.5 0.0 3.8 0.2 0.0 0.5 0.4 0.8 1.9 1.7 2.3 0.1 0.7 0.0 42.2 4.4 TNFRSF11B "OCIF, OPG, TR1" ENSG00000164761 "TNF receptor superfamily member 11b" O00300 8 118923557-118951885 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 29.9;thyroid gland: 101.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 134.3;Collecting duct cells: 73.5;Ductal cells: 32.7;Proximal tubular cells: 117.3" "Cancer enhanced" "Detected in all" "renal cancer: 22.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 40 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 40 "dendritic cells: 3.9" "Group enriched" "Detected in many" 4 "BJ: 546.7;BJ hTERT+: 2013.0" "Low region specificity" "Detected in all" CAB034939 Approved "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "CAB034939: " "unprognostic (1.39e-2)" "prognostic unfavorable (6.22e-4)" "unprognostic (5.27e-2)" "unprognostic (2.33e-2)" "unprognostic (4.27e-3)" "unprognostic (1.10e-3)" "unprognostic (1.21e-3)" "unprognostic (5.50e-2)" "unprognostic (9.94e-2)" "unprognostic (6.32e-2)" "unprognostic (3.53e-2)" "unprognostic (2.43e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.32e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (3.88e-4)" 3.3 3.3 2.6 5.3 3.1 0.0 2.6 2.6 4.1 1.1 3.5 2.5 1.4 10.2 0.5 0.4 1.4 5.8 9.4 2.5 2.7 29.9 14.2 9.4 7.0 5.0 3.0 0.3 1.8 0.5 1.8 4.9 3.3 1.6 3.5 0.3 1.4 1.0 0.4 0.5 2.2 2.6 3.1 2.6 1.2 0.1 3.0 1.3 101.8 0.8 2.9 10.7 0.3 3.8 0.0 0.9 8.6 0.0 27.5 5.3 0.0 546.7 2013.0 25.9 7.2 6.3 1.1 0.0 143.7 302.4 0.0 5.6 0.0 0.0 13.2 0.1 0.0 0.0 23.1 0.0 3.6 0.0 0.0 2.9 0.0 26.7 0.0 10.9 0.3 0.0 0.0 0.0 73.8 13.6 0.0 0.1 0.9 2.6 3.3 0.0 1.0 0.0 23.6 0.0 1.3 0.0 4.8 0.2 0.0 0.3 0.0 0.1 1.2 16.9 8.6 10.1 1.2 0.6 0.0 0.1 2.3 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 2.6 3.1 2.6 4.1 2.5 2.7 5.0 3.0 3.3 3.1 3.0 3.8 2.1 3.2 0.0 7.2 0.7 2.2 0.6 1.4 0.0 0.2 134.3 4.1 3.8 22.8 1.0 73.5 0.0 0.0 0.2 2.5 9.8 32.7 0.1 0.6 1.4 7.4 9.5 0.0 0.8 1.3 0.2 9.4 0.0 1.7 0.0 0.0 4.6 2.0 0.5 0.0 0.3 9.2 2.0 0.3 3.9 0.3 0.3 1.1 0.0 0.0 8.3 1.2 0.0 3.0 0.3 9.2 0.8 0.0 0.0 6.8 1.1 117.3 0.1 0.1 0.0 0.4 4.3 0.1 0.3 0.0 1.1 0.0 0.4 0.0 2.8 0.3 TNFRSF12A "CD266, FN14, TweakR" ENSG00000006327 "TNF receptor superfamily member 12A" Q9NP84 16 3018445-3022383 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 612.4;Basal prostatic cells: 1315.6;Basal respiratory cells: 622.2;Ductal cells: 938.2;Exocrine glandular cells: 698.4;Pancreatic endocrine cells: 1232.3;Prostatic glandular cells: 757.9;Urothelial cells: 695.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "eosinophil: 139.6;neutrophil: 102.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 139.6" "Cell line enhanced" "Detected in many" "U-251 MG: 699.6" HPA007853 Approved Approved "Plasma membrane,Cytosol" NA Yes 370000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA007853: AB_1858463" "unprognostic (1.44e-1)" "unprognostic (2.46e-3)" "unprognostic (8.90e-2)" "unprognostic (2.60e-1)" "unprognostic (4.06e-3)" "prognostic unfavorable (5.50e-4)" "unprognostic (7.04e-3)" "unprognostic (1.98e-3)" "unprognostic (4.17e-3)" "unprognostic (2.85e-1)" "unprognostic (5.02e-3)" "unprognostic (3.88e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.98e-2)" "unprognostic (6.00e-2)" "unprognostic (2.80e-3)" "unprognostic (2.17e-2)" 42.0 45.9 5.3 27.0 5.2 8.3 24.4 6.1 9.9 12.5 9.4 26.5 37.5 34.8 1.2 17.6 19.0 55.2 108.3 5.6 8.8 133.5 61.0 72.6 2.4 8.2 7.9 8.2 116.3 56.1 59.3 33.0 7.0 33.4 4.5 4.8 48.4 17.1 58.5 18.1 21.6 32.5 7.4 6.7 42.6 5.4 10.4 5.2 37.0 9.3 3.1 73.8 13.9 7.0 217.6 155.6 17.7 31.9 31.0 71.3 109.1 444.3 277.5 316.2 205.5 70.1 336.0 1.5 566.2 270.4 401.3 224.2 4.2 283.4 132.2 8.3 11.2 1.5 52.4 58.4 205.1 3.7 15.2 65.2 196.7 345.1 433.5 298.1 100.9 0.6 24.5 2.4 362.7 394.0 0.6 28.3 85.5 88.7 369.6 1.9 207.1 7.8 355.8 37.6 19.9 7.3 314.7 127.9 255.8 57.7 69.4 5.8 192.2 601.9 303.2 423.8 699.6 6.6 2.9 3.1 190.0 18.9 488.8 12.2 11.4 139.6 6.1 7.3 7.9 0.2 2.8 4.9 14.6 0.2 1.4 2.7 102.9 8.0 4.7 0.6 3.4 4.0 5.3 5.2 6.1 9.9 5.6 8.8 8.2 7.9 7.0 7.4 10.4 7.0 16.9 102.5 37.7 0.3 6.9 612.4 1315.6 622.2 113.3 1.5 139.0 46.7 63.9 195.9 238.7 182.1 2.1 134.6 10.0 74.2 64.6 938.2 1.3 170.5 29.4 47.5 27.3 1.3 0.2 698.4 169.5 155.1 33.1 173.1 59.1 3.0 24.3 20.7 39.7 0.0 0.5 19.9 152.5 5.6 121.4 0.8 6.2 23.0 112.1 1.9 10.8 23.3 4.1 0.0 0.1 1232.3 155.3 6.8 5.3 757.9 52.9 118.0 118.4 5.9 6.6 190.5 228.6 10.9 9.4 35.5 359.7 189.1 25.3 1.3 50.0 695.6 TNFRSF14 "ATAR, CD270, HVEA, HVEM, LIGHTR, TR2" ENSG00000157873 "TNF receptor superfamily member 14" Q92956 1 2555639-2565382 "Cancer-related genes, CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 16.2" "Low region specificity" "Detected in all" "HPA006404, CAB026150, CAB030007" Approved NA NA 110000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "CAB026150: , CAB030007: AB_2303380, HPA006404: AB_1851348" "prognostic favorable (4.39e-5)" "unprognostic (3.48e-2)" "unprognostic (1.53e-2)" "prognostic favorable (8.01e-6)" "unprognostic (1.11e-2)" "unprognostic (6.83e-3)" "unprognostic (9.62e-3)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (1.62e-1)" "unprognostic (2.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.86e-2)" "unprognostic (1.16e-2)" "unprognostic (2.72e-2)" "unprognostic (1.58e-1)" "prognostic favorable (7.79e-6)" 37.0 71.8 2.4 6.2 2.2 5.0 34.8 2.2 6.6 52.5 3.9 57.6 16.9 32.9 1.2 26.4 39.9 4.4 23.8 2.7 2.4 57.1 61.8 58.0 10.0 2.6 2.3 33.0 20.4 3.9 24.4 2.8 2.4 50.4 5.5 0.6 35.3 2.3 6.5 22.2 67.5 1.2 2.1 100.7 45.9 7.5 2.7 2.8 29.4 1.0 4.0 33.6 37.3 2.6 0.6 0.3 0.3 8.7 2.3 9.1 2.7 2.5 8.5 4.9 6.5 0.7 6.3 2.4 0.5 7.7 2.8 4.4 0.0 3.2 0.7 11.4 0.0 6.1 0.8 1.0 9.1 3.3 6.8 4.4 2.6 2.6 0.6 4.3 5.8 0.4 1.9 11.9 4.5 0.0 4.4 0.3 0.1 2.4 4.4 2.8 0.0 0.6 0.4 3.7 0.1 0.2 0.0 0.4 16.2 0.0 1.5 0.7 5.9 0.3 1.8 0.8 0.4 8.1 2.2 1.2 0.5 2.7 1.5 2.2 31.4 5.5 40.2 68.2 23.3 42.4 47.2 27.0 23.2 50.1 51.3 39.4 78.4 12.8 50.9 33.2 62.8 39.3 2.4 2.2 2.2 6.6 2.7 2.4 2.6 2.3 2.4 2.1 2.7 2.6 63.7 19.2 38.0 5.5 97.6 16.4 31.2 50.3 23.3 1.5 36.0 33.8 8.3 47.1 51.5 35.0 0.0 1.2 90.9 94.7 3.9 16.8 0.3 19.9 18.4 52.7 36.1 18.7 8.8 32.9 1.5 27.1 77.5 25.8 53.2 8.3 41.4 20.0 88.8 0.0 0.9 78.4 22.4 80.1 59.3 2.6 20.8 91.3 46.2 17.8 106.1 15.9 131.8 2.5 1.3 24.6 115.8 13.9 70.4 29.8 219.6 35.5 34.7 0.7 19.7 9.0 22.0 0.1 0.4 15.6 13.4 1.2 84.4 16.0 101.4 44.3 TNFRSF18 "AITR, CD357, GITR" ENSG00000186891 "TNF receptor superfamily member 18" Q9Y5U5 1 1203508-1206592 "CD markers, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 189.0;dendritic cells: 72.2;Langerhans cells: 86.4;Melanocytes: 49.8;Plasma cells: 55.3;Suprabasal keratinocytes: 150.6;T-cells: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cell: 184.5;T-reg: 71.8" "Group enriched" "Detected in many" 11 "NK-cells: 184.5;T-cells: 71.8" "Group enriched" "Detected in some" 12 "RPMI-8226: 225.6;SCLC-21H: 152.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008025 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA008025: AB_1849696" "unprognostic (1.20e-3)" "unprognostic (4.61e-2)" "unprognostic (4.59e-2)" "prognostic favorable (7.72e-6)" "unprognostic (2.73e-4)" "prognostic favorable (4.12e-4)" "unprognostic (3.43e-2)" "unprognostic (2.31e-1)" "unprognostic (3.33e-2)" "unprognostic (1.01e-1)" "unprognostic (1.00e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (4.40e-11)" "unprognostic (1.02e-3)" "unprognostic (2.39e-1)" "unprognostic (3.74e-1)" "unprognostic (2.08e-1)" 1.9 0.6 1.1 7.3 1.3 2.9 2.4 2.5 3.1 11.1 0.7 6.0 7.2 1.4 0.0 6.3 1.4 0.9 0.5 1.0 0.6 2.8 0.9 4.6 5.5 1.3 0.6 0.3 0.3 9.4 4.9 0.3 1.3 2.8 1.5 0.0 5.6 0.6 0.8 38.5 7.1 0.3 0.6 9.0 5.2 0.9 0.9 1.9 1.4 0.0 3.8 2.0 3.3 1.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 1.7 0.1 0.0 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.3 1.2 0.1 0.5 16.1 0.1 0.1 225.6 0.3 0.0 152.8 0.2 0.0 0.6 0.0 0.0 8.2 0.1 0.0 0.0 0.3 0.2 0.0 0.9 0.3 0.2 0.6 0.1 0.0 0.2 0.2 0.0 6.8 0.1 12.6 4.6 28.9 4.4 0.1 11.5 0.9 1.5 0.8 184.5 0.1 0.3 71.8 6.7 1.1 1.3 2.5 3.1 1.0 0.6 1.3 0.6 1.3 0.6 0.9 1.2 11.2 0.0 1.3 0.3 23.5 189.0 12.5 15.5 16.5 0.0 5.0 3.0 2.9 0.0 3.2 0.0 0.0 0.0 72.2 0.3 0.0 0.8 0.0 1.2 1.2 4.1 3.5 0.0 2.0 0.6 1.3 4.7 1.1 2.9 45.7 0.0 0.7 0.0 0.8 0.0 0.3 0.2 20.3 0.3 86.4 0.0 0.0 5.4 49.8 0.0 12.7 0.0 21.6 0.5 0.3 0.4 0.0 0.0 55.3 10.1 0.1 0.1 0.8 0.0 0.0 6.2 2.2 0.0 0.0 0.3 150.6 0.0 75.7 0.0 0.8 7.0 TNFRSF1A "CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60" ENSG00000067182 "TNF receptor superfamily member 1A" P19438 12 6328757-6342114 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" Receptor "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 507.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004102, CAB010309" Approved "Secreted to blood" NA NA 17700 570000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB010309: AB_2206639, HPA004102: AB_1846232" "unprognostic (2.19e-2)" "unprognostic (3.76e-2)" "unprognostic (8.14e-2)" "prognostic favorable (8.22e-4)" "unprognostic (3.07e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.50e-1)" "unprognostic (1.41e-3)" "unprognostic (1.00e-1)" "unprognostic (8.05e-2)" "unprognostic (4.78e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (2.70e-7)" "unprognostic (1.43e-2)" "unprognostic (2.92e-2)" "unprognostic (5.14e-3)" "unprognostic (1.74e-1)" 166.5 133.3 33.7 76.7 34.4 42.4 120.0 35.3 38.6 105.0 47.8 114.1 101.5 111.8 23.0 105.6 106.7 88.8 80.6 32.4 40.3 94.5 176.5 130.7 38.1 45.7 40.4 90.6 57.3 53.7 57.3 82.4 39.6 86.9 56.4 3.5 76.0 46.3 91.0 103.7 109.5 97.5 40.4 111.3 84.4 22.6 39.7 39.2 97.4 63.1 36.1 113.2 113.2 37.4 40.2 296.4 40.9 60.2 277.7 282.0 75.7 82.2 143.0 108.2 93.9 34.7 153.6 3.7 28.9 179.3 85.6 107.1 12.9 96.4 74.1 0.8 25.3 20.3 79.2 82.2 245.5 104.4 66.9 291.8 94.4 90.2 131.4 250.4 134.1 42.0 33.7 29.8 126.3 57.1 34.0 100.0 102.1 146.1 87.6 27.9 66.6 32.4 83.7 70.7 0.1 2.1 117.8 60.9 62.5 103.6 16.4 111.4 146.0 84.6 71.7 64.7 78.4 0.1 10.6 12.8 100.5 95.9 107.0 17.1 165.8 93.5 62.2 130.4 60.0 0.5 25.1 51.0 123.7 0.4 22.3 34.0 507.2 9.7 111.5 31.6 26.2 117.3 33.7 34.4 35.3 38.6 32.4 40.3 45.7 40.4 39.6 40.4 39.7 37.4 102.0 51.3 37.1 15.3 4.8 123.0 115.8 127.3 81.4 0.4 50.1 35.9 9.3 67.2 70.8 27.6 0.0 62.0 35.5 204.0 15.6 98.7 1.2 25.5 66.5 111.8 33.6 30.1 4.6 119.4 120.2 109.3 43.8 42.3 7.6 27.6 159.2 145.0 176.4 0.0 1.3 56.8 32.6 146.7 113.4 5.4 102.2 102.4 71.2 32.8 127.1 15.9 104.0 11.1 0.9 116.6 239.4 65.8 4.2 141.2 227.5 96.9 30.8 0.7 124.9 64.1 89.4 1.3 1.1 57.0 134.7 148.6 31.2 21.5 57.4 140.1 TNFRSF1B "CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80" ENSG00000028137 "TNF receptor superfamily member 1B" P20333 1 12166991-12209228 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.4" "Cell type enhanced" "Detected in many" "dendritic cells: 268.7;Kupffer cells: 200.5;Langerhans cells: 288.0;Macrophages: 230.2;monocytes: 175.3;T-cells: 138.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 387.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 34.0;K-562: 45.7;THP-1: 51.8;U-87 MG: 30.8;U-937: 37.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004796 Approved "Secreted to blood" NA NA 3230000 8100000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA004796: AB_1078436" "unprognostic (4.45e-2)" "unprognostic (2.27e-3)" "unprognostic (7.62e-2)" "unprognostic (3.82e-3)" "unprognostic (6.30e-2)" "unprognostic (4.47e-3)" "unprognostic (5.28e-3)" "unprognostic (2.79e-1)" "unprognostic (1.69e-2)" "unprognostic (1.73e-2)" "unprognostic (7.26e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.26e-2)" "unprognostic (1.10e-1)" 45.6 5.4 3.9 68.4 3.8 52.1 34.7 4.8 17.9 14.3 5.6 12.8 16.8 11.6 0.4 5.5 14.6 15.6 10.9 3.7 9.0 7.5 15.7 32.0 32.1 18.3 7.2 6.3 5.9 2.3 4.5 35.8 10.6 6.4 10.8 0.8 6.5 2.6 10.7 7.8 23.9 16.8 9.0 53.3 16.4 2.2 8.9 12.7 7.6 6.3 21.3 28.9 8.8 14.1 0.0 0.3 4.1 0.0 9.6 13.5 8.9 1.1 2.0 4.0 4.3 1.8 34.0 0.2 0.6 3.9 5.6 0.0 0.8 0.0 2.2 14.5 0.0 0.0 0.2 0.0 25.2 0.3 3.8 14.8 0.0 13.0 0.0 7.2 19.6 0.2 45.7 6.4 1.5 0.0 0.0 8.1 0.2 4.9 1.4 1.2 0.4 25.9 0.0 0.8 0.0 0.1 0.6 0.4 1.4 6.4 0.0 51.8 7.8 5.3 0.2 27.0 0.0 1.9 0.0 0.0 30.8 37.0 1.4 0.6 127.1 18.2 48.4 260.5 26.5 13.5 34.4 40.5 71.7 8.4 9.8 15.5 138.0 13.4 387.1 15.1 70.9 150.4 3.9 3.8 4.8 17.9 3.7 9.0 18.3 7.2 10.6 9.0 8.9 14.1 99.4 9.6 15.9 0.7 42.8 16.8 3.9 1.0 1.2 0.2 3.2 4.1 3.6 5.7 6.5 3.7 0.0 0.9 268.7 12.8 0.0 0.5 0.6 1.7 5.1 46.0 0.0 7.4 0.2 0.6 6.3 13.2 12.8 4.9 2.5 1.4 31.1 17.0 72.6 0.0 0.2 3.0 0.0 200.5 288.0 1.2 2.1 230.2 16.0 30.9 175.3 0.3 109.2 0.0 0.1 0.7 4.2 0.4 72.5 8.0 25.8 0.4 1.5 1.2 32.9 6.8 9.8 0.0 0.9 0.7 10.5 30.1 138.4 1.9 4.8 8.8 TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.0;pituitary gland: 29.9;skin 1: 25.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 34.1;Excitatory neurons: 37.5;T-cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Cell line enhanced" "Detected in many" "HDLM-2: 20.5;RPMI-8226: 25.7" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Not detected" "Not detected" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (8.09e-3)" "unprognostic (6.91e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (1.97e-1)" "unprognostic (9.63e-3)" "prognostic favorable (3.09e-4)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (6.01e-2)" "unprognostic (3.98e-2)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (8.68e-3)" 6.4 4.2 4.0 3.2 4.0 0.8 4.0 11.1 6.1 5.2 4.9 6.1 3.0 3.0 0.6 10.3 5.7 2.2 8.7 4.8 4.3 3.3 1.2 2.4 4.3 3.7 3.6 3.1 1.5 0.9 29.9 4.4 4.4 5.2 1.4 1.2 3.3 2.3 1.1 25.3 5.0 0.5 3.3 44.0 2.0 0.9 3.7 2.0 3.2 1.2 2.7 2.5 4.6 3.5 1.8 0.4 1.1 2.0 0.0 0.6 1.3 1.5 0.6 0.3 0.0 1.7 2.8 0.0 2.5 0.0 1.3 4.2 0.6 4.7 0.0 20.5 1.5 0.6 1.7 0.1 0.7 0.0 0.1 0.0 3.2 1.5 4.1 2.7 4.0 1.1 0.0 0.0 0.0 2.2 0.0 8.0 1.4 1.4 3.4 0.6 0.3 25.7 1.3 0.7 3.4 5.3 0.0 2.5 0.1 0.6 2.0 2.9 2.5 1.3 2.1 0.0 2.0 0.0 3.5 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.0 0.2 5.6 0.0 4.4 2.2 0.5 0.0 4.4 0.7 0.0 0.8 1.0 0.0 7.9 0.9 4.0 4.0 11.1 6.1 4.8 4.3 3.7 3.6 4.4 3.3 3.7 3.5 19.0 3.2 5.0 3.9 2.5 24.6 2.3 5.6 11.4 3.1 4.2 5.5 1.1 1.5 3.3 1.8 2.1 0.7 12.8 34.1 0.0 0.2 0.2 4.1 11.2 11.5 6.7 3.0 37.5 0.4 2.0 2.3 5.6 6.9 7.0 4.8 7.9 1.1 4.0 5.0 21.6 20.3 0.0 1.2 6.6 0.3 2.8 4.0 7.2 14.0 3.0 10.2 10.3 7.5 2.1 1.4 16.0 9.4 3.2 3.7 9.8 0.6 4.8 9.1 0.0 2.6 2.6 0.4 1.2 8.6 28.6 0.1 41.4 0.7 25.0 6.8 TNFRSF6B "DcR3, M68, TR6" ENSG00000243509 "TNF receptor superfamily member 6b" O95407 20 63696652-63698684 "Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 51.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 21.6" "Lineage enriched" "Detected in many" 16 "dendritic cells: 21.6" "Group enriched" "Detected in some" 4 "HBEC3-KT: 28.3;RPTEC TERT1: 110.7;TIME: 69.0" HPA047154 Approved "Secreted to blood" NA NA 406000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "HPA047154: AB_2679959" 30.9 5.1 14.4 14.3 11.9 0.2 24.7 11.5 18.2 7.8 7.4 13.7 0.0 8.0 0.0 11.7 9.6 0.5 7.7 11.4 14.7 16.6 5.5 51.2 1.2 17.0 12.9 7.3 8.3 0.0 15.4 0.0 16.8 10.6 0.1 0.0 10.2 0.0 7.1 13.8 16.1 0.9 15.0 39.3 9.8 6.8 18.7 0.0 12.3 0.0 3.4 16.0 9.6 11.4 0.0 0.5 0.0 0.0 0.0 0.2 1.5 1.8 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.5 0.0 0.0 9.4 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.8 0.0 0.0 0.0 110.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.2 69.0 0.0 1.5 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 1.3 21.6 0.1 0.1 14.4 11.9 11.5 18.2 11.4 14.7 17.0 12.9 16.8 15.0 18.7 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TNFRSF9 "4-1BB, CD137, ILA" ENSG00000049249 "TNF receptor superfamily member 9" Q07011 1 7915871-7943165 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 9.9" "Cell type enhanced" "Detected in some" "dendritic cells: 15.0;granulocytes: 63.4;Langerhans cells: 17.5;monocytes: 31.6;T-cells: 29.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "memory CD8 T-cell: 9.4;neutrophil: 7.8;NK-cell: 5.2;T-reg: 18.5" "Group enriched" "Detected in many" 5 "granulocytes: 7.8;NK-cells: 5.2;T-cells: 18.5" "Cell line enriched" "Detected in some" 9 "HDLM-2: 111.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA071425 Approved "Nucleoli,Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Nucleoli "HPA071425: AB_2686394" "unprognostic (7.23e-2)" "unprognostic (1.72e-2)" "unprognostic (8.26e-3)" "unprognostic (1.32e-3)" "unprognostic (1.10e-1)" "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-4)" "unprognostic (9.47e-3)" "unprognostic (2.17e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.69e-8)" "unprognostic (1.64e-2)" "unprognostic (2.25e-2)" "unprognostic (1.19e-1)" "unprognostic (9.55e-2)" 0.5 0.2 0.4 3.9 0.4 2.2 0.2 1.1 0.5 0.2 0.3 0.5 0.5 0.3 0.2 0.6 0.1 1.6 0.2 0.4 0.1 0.2 0.7 0.8 9.0 0.3 0.1 0.2 0.7 0.0 0.0 0.2 0.3 0.3 1.1 0.5 0.3 0.2 0.2 0.5 0.8 0.2 0.0 4.1 0.8 0.2 0.3 3.7 0.2 0.2 9.9 1.9 0.0 1.1 2.5 0.9 0.2 0.2 0.0 0.1 0.1 0.1 0.4 0.5 0.5 3.1 0.5 0.1 1.2 0.1 1.8 0.4 0.0 0.4 1.9 111.5 0.2 0.6 0.5 0.1 1.8 0.0 0.9 0.3 0.7 0.5 0.2 0.4 0.1 0.1 0.4 0.3 0.1 0.2 0.0 0.3 0.1 0.1 0.2 0.1 0.7 0.2 0.3 0.1 0.2 0.2 0.4 0.2 0.0 1.3 0.1 0.3 0.3 0.3 3.2 0.1 0.5 0.2 0.2 0.2 13.0 0.8 0.1 1.5 1.9 0.2 1.7 0.6 0.3 0.3 1.1 9.4 1.4 0.4 0.2 1.7 7.8 5.2 0.1 0.3 18.5 1.4 0.4 0.4 1.1 0.5 0.4 0.1 0.3 0.1 0.3 0.0 0.3 1.1 0.6 0.0 1.7 0.0 1.6 0.3 0.9 0.3 0.6 0.0 0.3 0.5 0.4 0.0 1.9 0.0 0.0 0.0 15.0 0.1 0.0 1.3 0.0 0.6 1.0 0.8 0.0 0.0 0.2 1.1 0.0 1.0 3.6 1.4 63.4 0.0 0.0 0.0 0.8 0.0 0.3 0.2 0.0 0.3 17.5 0.0 0.0 3.6 5.4 0.0 31.6 0.0 1.0 0.0 0.1 2.0 0.1 0.0 9.4 0.5 0.0 0.1 0.0 0.0 0.0 7.7 1.0 0.4 0.1 0.1 0.4 0.0 29.2 0.0 0.5 0.3 TNFSF10 "Apo-2L, CD253, TL2, TRAIL" ENSG00000121858 "TNF superfamily member 10" P50591 3 172505508-172523475 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 732.8;Exocrine glandular cells: 424.6;Proximal tubular cells: 556.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 265.4;classical monocyte: 133.4;intermediate monocyte: 203.5;neutrophil: 257.1;non-classical monocyte: 213.2" "Group enriched" "Detected in all" 5 "granulocytes: 265.4;monocytes: 213.2" "Cell line enhanced" "Detected in many" "BEWO: 73.1;CAPAN-2: 53.7;HaCaT: 51.5;HMC-1: 244.5;RPTEC TERT1: 122.1" "Low region specificity" "Detected in all" HPA054938 Uncertain "Secreted to blood" NA NA 67400 18000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA054938: AB_2682643" "unprognostic (9.16e-2)" "unprognostic (2.79e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-3)" "unprognostic (2.52e-1)" "unprognostic (2.67e-1)" "unprognostic (1.55e-1)" "unprognostic (2.01e-1)" "unprognostic (1.99e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (9.43e-4)" "unprognostic (1.04e-1)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (3.68e-2)" "unprognostic (1.32e-1)" "unprognostic (6.27e-2)" 51.0 49.9 9.5 55.4 9.8 14.8 84.5 9.8 17.0 37.3 17.3 76.8 100.3 47.1 19.6 66.4 39.1 45.3 31.7 9.0 9.9 145.1 209.0 177.2 54.7 12.0 10.2 27.1 22.2 77.7 10.4 167.9 11.0 86.7 91.4 1.4 127.9 42.7 20.7 54.6 95.2 26.3 11.0 70.9 47.3 4.8 10.3 34.2 29.3 61.7 46.8 70.3 62.4 10.6 12.4 0.6 0.1 0.2 8.2 6.6 73.1 0.0 0.5 3.7 5.9 0.3 53.7 7.9 34.7 0.0 3.2 51.5 0.3 6.3 0.7 19.6 0.2 0.2 1.5 1.1 0.4 14.7 244.5 8.2 8.0 1.3 0.2 0.0 25.6 1.6 0.3 8.7 0.0 0.1 1.9 19.4 0.3 0.2 0.5 2.9 0.2 3.5 122.1 4.6 0.3 0.5 27.2 1.0 0.6 0.4 15.3 8.0 1.1 0.1 0.2 0.1 0.7 9.3 1.1 9.5 0.6 8.0 0.2 265.4 133.4 14.7 10.9 203.5 15.0 16.7 30.4 16.8 49.1 18.2 21.6 8.5 257.1 49.3 213.2 2.9 36.8 73.6 9.5 9.8 9.8 17.0 9.0 9.9 12.0 10.2 11.0 11.0 10.3 10.6 326.5 70.5 114.4 0.0 26.2 22.0 169.5 398.4 69.4 0.3 146.5 97.3 7.9 84.4 281.1 66.2 0.0 6.6 20.7 294.2 45.0 732.8 4.5 60.5 18.2 247.5 48.3 9.7 0.1 424.6 189.4 69.2 44.9 121.0 257.0 2.4 186.7 75.2 23.5 1.7 0.1 111.3 175.0 79.8 23.7 3.8 18.3 70.5 7.2 52.5 160.3 18.7 52.5 0.0 0.1 244.0 216.4 4.9 23.2 82.7 317.0 556.7 114.5 1.5 0.0 6.5 22.3 0.1 0.3 103.1 25.6 10.9 51.8 19.7 74.3 170.1 TNFSF11 "CD254, ODF, OPGL, RANKL, TRANCE" ENSG00000120659 "TNF superfamily member 11" O14788 13 42562736-42608013 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Cytokine, Developmental protein, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 4.5;liver: 5.2;lymphoid tissue: 15.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 10.8;Breast myoepithelial cells: 5.1;Ductal cells: 6.2;Early spermatids: 8.0;Late spermatids: 15.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "NK-cell: 13.6" "Lineage enriched" "Detected in many" 7 "NK-cells: 13.6" "Cell line enhanced" "Detected in some" "HSkMC: 2.1;NTERA-2: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB009193, HPA045142" Enhanced "Secreted to blood" NA NA 17200 "Cluster 15: NK-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 35: Glandular cells - Unknown function" "CAB009193: , HPA045142: AB_2679231" "unprognostic (3.97e-4)" "unprognostic (1.40e-1)" "unprognostic (9.01e-3)" "unprognostic (3.81e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (7.09e-2)" "unprognostic (7.70e-2)" "unprognostic (2.29e-1)" "unprognostic (1.25e-3)" "unprognostic (1.00e-1)" "unprognostic (1.50e-1)" "unprognostic (3.94e-5)" "unprognostic (1.87e-1)" "unprognostic (9.67e-2)" "unprognostic (5.46e-2)" "unprognostic (7.74e-2)" 0.2 0.0 0.0 4.8 0.0 0.2 4.5 0.0 0.1 0.8 0.2 0.9 0.4 0.1 0.0 0.1 0.0 1.4 0.1 0.0 0.1 0.1 5.2 0.1 15.2 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.4 1.1 0.0 0.1 1.9 0.0 0.0 0.6 0.5 1.3 0.1 1.5 0.0 0.1 5.0 1.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.4 0.1 0.0 0.3 0.0 0.0 10.8 5.1 0.4 1.5 0.2 0.0 0.0 0.0 2.3 0.0 0.0 6.2 8.0 0.5 0.1 0.1 1.2 0.0 0.2 0.2 0.0 0.2 0.0 0.7 0.0 0.3 0.0 1.0 0.0 0.0 0.7 0.9 0.0 0.0 0.4 15.3 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 3.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 0.0 0.3 0.0 1.8 0.0 0.0 0.0 TNFSF12 "APO3L, DR3LG, TWEAK" ENSG00000239697 "TNF superfamily member 12" O43508 17 7549058-7557890 "Predicted secreted proteins" "Angiogenesis, Apoptosis, Differentiation" "Cytokine, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 17.7;BJ hTERT+: 18.4;HDLM-2: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035984, HPA052967" Uncertain Approved Vesicles "Secreted to blood" NA NA 853000 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA035984: , HPA052967: AB_2682000" "unprognostic (2.96e-3)" "unprognostic (2.96e-1)" "unprognostic (4.71e-2)" "prognostic favorable (5.70e-5)" "unprognostic (5.31e-2)" "unprognostic (7.91e-2)" "unprognostic (6.45e-2)" "unprognostic (2.38e-2)" "unprognostic (4.48e-2)" "unprognostic (6.09e-2)" "unprognostic (6.20e-2)" "unprognostic (8.62e-2)" "unprognostic (3.29e-2)" "unprognostic (4.11e-2)" "unprognostic (3.15e-2)" "unprognostic (8.74e-2)" "unprognostic (2.38e-1)" 41.6 28.5 57.4 9.8 55.3 3.1 36.6 49.4 66.5 37.6 48.9 68.2 9.7 38.2 7.0 13.9 37.7 15.6 39.6 54.8 50.4 32.9 16.5 37.7 15.8 55.7 54.2 42.7 23.2 11.1 18.0 11.2 53.2 39.4 5.7 2.9 26.1 27.2 16.9 15.8 26.7 13.3 52.8 38.4 38.8 5.6 57.0 4.8 22.9 9.3 5.5 47.1 30.1 52.1 0.0 0.5 0.7 0.0 14.9 17.7 4.0 6.9 18.4 7.7 5.7 0.1 2.5 0.0 5.8 16.3 0.8 1.4 1.4 0.6 1.6 20.3 2.0 0.9 0.4 2.3 12.8 0.0 0.0 15.0 2.6 2.8 0.3 3.0 12.1 0.0 0.0 0.0 7.0 0.0 0.0 0.5 0.6 0.1 7.5 0.1 0.0 0.1 11.6 0.0 0.0 7.9 2.5 0.0 12.6 0.1 1.4 0.6 16.1 15.1 1.1 0.1 8.8 0.0 0.0 0.0 2.4 0.0 10.5 2.6 3.5 11.6 5.1 5.9 6.0 2.9 4.3 3.1 2.2 1.8 4.1 4.2 2.0 2.8 1.5 2.5 4.0 1.1 57.4 55.3 49.4 66.5 54.8 50.4 55.7 54.2 53.2 52.8 57.0 52.1 115.9 9.6 12.2 0.0 20.4 6.1 11.1 1.5 6.8 6.7 21.7 41.7 4.3 17.2 3.4 16.5 0.0 1.6 38.3 2.5 7.9 15.2 0.4 4.1 15.2 33.9 1.2 3.2 0.0 12.1 0.8 42.7 4.6 8.5 34.3 6.8 48.5 3.4 44.3 20.2 0.0 3.4 0.0 59.7 26.8 1.2 50.7 62.1 19.6 0.0 28.6 46.6 40.2 0.0 0.0 8.1 1.7 50.4 3.6 6.7 0.4 39.6 0.6 2.6 59.2 34.4 56.7 0.2 1.1 2.1 7.5 0.8 38.7 9.4 4.1 6.0 TNFSF12-TNFSF13 TWE-PRIL ENSG00000248871 "TNFSF12-TNFSF13 readthrough" 17 7549099-7561601 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 9.1;choroid plexus: 5.7" "Group enriched" "Detected in some" 17 "Alveolar cells type 2: 3.7;Club cells: 3.7;granulocytes: 3.8;Macrophages: 4.5;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 7.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.7;fHDF/TERT166: 1.3;HUVEC TERT2: 1.1;U-138 MG: 1.7;U-251 MG: 1.7" "Low region specificity" "Detected in all" "HPA004863, HPA035984, HPA052967" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA004863: AB_1078187, HPA035984: , HPA052967: AB_2682000" "unprognostic (1.59e-1)" "unprognostic (1.48e-1)" "unprognostic (2.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "unprognostic (3.04e-1)" "unprognostic (2.19e-1)" "unprognostic (1.05e-2)" "unprognostic (1.40e-1)" "unprognostic (8.96e-3)" "unprognostic (1.38e-2)" "unprognostic (2.05e-1)" "unprognostic (8.23e-2)" 4.0 1.3 4.7 0.7 4.7 0.7 1.8 4.5 9.1 0.7 5.7 1.4 0.2 0.4 0.0 0.3 0.4 0.1 2.3 4.5 5.0 2.3 0.7 4.6 1.0 5.1 5.1 0.4 0.5 0.1 0.4 0.2 4.7 0.7 0.0 0.1 0.6 0.2 0.7 0.8 0.8 0.3 4.6 3.1 0.7 0.1 5.0 0.2 0.4 0.0 0.5 1.1 0.3 4.8 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.5 1.7 0.6 0.9 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.5 0.0 0.0 0.0 0.5 1.7 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.0 0.2 0.4 2.4 7.2 0.2 4.5 0.3 0.7 0.5 0.3 1.8 1.5 0.3 0.1 0.3 0.2 0.2 0.9 1.0 1.4 4.7 4.7 4.5 9.1 4.5 5.0 5.1 5.1 4.7 4.6 5.0 4.8 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TNFSF13 "APRIL, CD256" ENSG00000161955 "TNF superfamily member 13" O75888 17 7558292-7561608 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 141.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 10.4;Basal squamous epithelial cells: 8.0;Erythroid cells: 5.9;Gastric mucus-secreting cells: 11.2;Macrophages: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 438.1;intermediate monocyte: 420.9" "Group enriched" "Detected in all" 12 "dendritic cells: 283.5;granulocytes: 158.9;monocytes: 438.1" "Cell line enhanced" "Detected in many" "EFO-21: 43.6;RPMI-8226: 39.9;RPTEC TERT1: 110.6;U-937: 44.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004863 Uncertain "Secreted to blood" NA NA 6770000 35000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "HPA004863: AB_1078187" "unprognostic (2.46e-2)" "unprognostic (2.20e-1)" "unprognostic (3.42e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (3.57e-1)" "unprognostic (3.32e-2)" "unprognostic (3.70e-2)" "unprognostic (3.75e-1)" "unprognostic (1.15e-1)" "unprognostic (6.95e-2)" "unprognostic (2.65e-1)" "prognostic favorable (1.30e-9)" "unprognostic (4.69e-2)" "unprognostic (1.42e-2)" "unprognostic (3.46e-1)" "unprognostic (3.38e-2)" 27.7 31.6 39.5 37.7 43.7 48.4 29.5 39.7 47.3 33.5 66.7 45.9 74.7 13.3 19.2 12.5 31.8 54.1 18.0 35.3 37.6 55.6 16.2 100.7 33.1 44.8 43.3 24.8 41.1 18.0 19.7 14.7 41.1 22.6 41.9 13.0 141.9 32.1 5.3 10.5 39.5 24.8 40.0 30.6 54.0 4.6 44.8 14.1 27.0 10.1 24.5 26.0 15.5 38.8 20.8 8.3 2.8 5.5 3.2 1.7 3.4 3.7 2.7 1.5 1.3 4.6 12.8 9.1 43.6 3.8 5.2 13.1 0.1 3.6 1.6 16.2 7.0 5.9 18.2 9.7 6.7 5.1 5.9 3.6 3.6 1.0 5.7 8.8 4.7 6.5 4.6 3.5 1.3 3.1 2.3 16.6 2.7 20.3 6.0 16.5 3.4 39.9 110.6 13.5 5.1 4.9 7.2 18.8 2.5 4.1 25.2 12.4 2.4 4.8 5.8 2.1 8.1 0.8 2.8 2.4 1.9 44.1 9.5 75.2 438.1 158.9 0.9 420.9 0.8 13.7 0.5 0.7 283.5 25.0 2.4 1.5 56.9 7.9 265.4 130.8 0.9 257.1 39.5 43.7 39.7 47.3 35.3 37.6 44.8 43.3 41.1 40.0 44.8 38.8 0.2 6.4 10.4 0.0 2.1 0.0 0.2 0.2 8.0 0.1 0.4 0.1 0.0 0.0 2.0 1.8 0.0 0.0 0.1 1.0 0.0 0.4 0.0 0.2 0.1 0.0 1.2 5.9 0.0 0.2 0.0 2.9 11.2 0.4 2.5 0.1 0.0 0.0 0.4 0.0 0.0 0.6 0.0 1.2 0.0 0.0 0.0 19.5 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.2 0.7 0.3 1.5 0.2 0.0 0.1 0.2 0.0 0.0 2.6 0.0 0.0 0.8 0.1 0.6 0.2 TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.5;Kupffer cells: 141.1;Langerhans cells: 246.7;Macrophages: 170.4;monocytes: 509.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 505.4" "Group enriched" "Detected in all" 11 "dendritic cells: 206.4;granulocytes: 505.4;monocytes: 350.9" "Cell line enriched" "Detected in some" 7 "U-937: 167.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 393000 790000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (6.48e-2)" "unprognostic (3.05e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (2.61e-2)" "unprognostic (7.99e-2)" "unprognostic (8.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.53e-11)" "unprognostic (1.23e-1)" "unprognostic (4.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" 8.2 5.3 2.8 25.9 2.6 20.1 4.7 2.7 4.1 2.2 5.8 5.5 10.7 1.4 1.5 4.8 2.4 12.4 3.8 2.7 3.1 1.5 5.3 10.9 20.9 6.3 3.0 1.1 1.5 0.7 1.0 9.0 4.2 1.7 8.4 0.4 3.3 1.2 1.4 1.9 6.4 5.0 4.6 15.9 5.0 1.2 3.5 5.3 3.0 1.6 17.7 11.1 2.1 5.2 0.1 0.4 0.1 0.1 0.7 0.8 0.2 0.3 0.8 0.6 2.1 0.1 1.7 0.3 0.2 0.2 0.3 0.1 0.0 0.1 0.1 11.6 0.0 0.9 0.4 0.0 0.4 10.2 0.3 2.0 0.4 0.2 0.1 0.4 0.1 0.1 0.1 0.6 1.2 0.0 0.1 5.3 0.1 1.1 0.0 0.0 0.2 0.0 0.6 0.3 1.3 0.3 0.0 0.0 0.4 0.2 0.1 22.3 0.2 0.3 0.0 0.0 0.4 10.0 0.3 0.1 10.3 167.0 1.7 12.6 350.9 100.1 5.4 272.3 31.5 4.4 21.5 4.4 206.4 7.1 9.9 3.4 505.4 5.0 234.1 77.8 19.4 165.8 2.8 2.6 2.7 4.1 2.7 3.1 6.3 3.0 4.2 4.6 3.5 5.2 3.1 16.0 12.9 6.2 7.0 7.1 0.7 1.3 1.2 0.9 2.4 3.2 0.6 10.0 4.2 5.5 0.0 0.5 40.6 0.6 1.9 2.3 1.2 0.4 0.7 3.6 1.2 14.5 18.1 32.5 1.1 29.6 3.1 0.5 5.1 0.9 3.9 2.8 87.5 0.0 11.2 0.9 0.0 141.1 246.7 0.6 5.3 170.4 8.8 15.0 509.4 0.2 5.2 55.3 5.1 1.7 0.5 1.9 1.5 2.7 2.2 1.3 2.0 0.3 6.6 1.4 4.1 0.1 0.7 0.5 4.7 1.1 10.5 1.2 1.8 3.1 TNFSF15 "MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A" ENSG00000181634 "TNF superfamily member 15" O95150 9 114784652-114806039 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 25.6;Basal squamous epithelial cells: 14.8;Endometrial ciliated cells: 15.7;Glandular and luminal cells: 28.9;Squamous epithelial cells: 13.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 13.2;hTEC/SVTERT24-B: 8.6;HUVEC TERT2: 16.7;OE19: 16.0;RT4: 16.5;TIME: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012948, HPA046522" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Secreted to blood" NA NA 1110000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA012948: AB_1858024, HPA046522: AB_2679683" "unprognostic (3.41e-1)" "unprognostic (2.06e-2)" "unprognostic (3.76e-1)" "unprognostic (1.52e-2)" "unprognostic (3.26e-2)" "unprognostic (1.67e-2)" "unprognostic (1.64e-1)" "unprognostic (2.29e-2)" "unprognostic (5.40e-2)" "unprognostic (1.38e-1)" "unprognostic (7.78e-2)" "unprognostic (2.09e-1)" "unprognostic (8.64e-5)" "unprognostic (1.97e-2)" "unprognostic (1.87e-3)" "unprognostic (1.68e-3)" "unprognostic (4.46e-3)" 0.8 0.7 0.1 2.5 0.2 0.1 0.9 0.1 0.5 1.5 0.1 2.3 9.5 1.0 0.9 1.2 0.9 1.9 0.0 0.1 0.2 4.5 0.2 4.1 0.8 0.3 0.1 0.1 0.1 0.8 0.1 4.4 0.2 4.1 2.0 0.0 4.8 1.9 0.1 0.6 3.5 2.0 0.0 0.5 2.9 0.1 0.2 0.6 0.9 0.0 1.0 4.7 0.7 0.4 0.5 4.4 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.1 0.2 3.0 1.6 0.0 0.0 0.5 13.2 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 8.6 0.0 0.0 16.7 0.0 0.0 0.9 0.4 0.6 0.0 0.0 0.3 16.0 0.0 0.0 0.1 0.0 0.1 16.5 0.1 0.0 0.0 0.7 0.0 5.6 1.2 0.0 7.7 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.1 0.5 0.1 0.2 0.3 0.1 0.2 0.0 0.2 0.4 0.2 12.8 12.1 0.0 0.1 0.5 7.7 25.6 14.8 0.3 3.7 3.7 0.6 1.5 4.9 7.3 0.0 0.7 0.4 8.0 0.0 4.9 0.7 15.7 2.9 0.3 0.0 0.0 0.1 2.0 0.2 1.2 8.2 28.9 0.0 0.0 0.0 0.0 2.3 0.0 0.7 2.4 2.0 0.3 5.1 0.1 0.0 5.0 0.0 0.0 5.3 0.1 0.0 0.0 0.1 1.3 0.5 0.4 1.2 4.9 8.9 9.3 1.0 0.3 0.0 0.4 3.0 0.0 0.0 13.7 0.6 0.3 1.0 0.1 7.4 6.5 TNFSF4 "CD252, gp34, OX-40L, TXGP1" ENSG00000117586 "TNF superfamily member 4" P23510 1 173183731-173207331 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins" Cytokine "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Granulosa cells: 37.0;Macrophages: 26.4;monocytes: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 42.0;HHSteC: 17.3;HUVEC TERT2: 81.2;LHCN-M2: 67.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059579 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" "HPA059579: AB_2684071" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (4.58e-2)" "unprognostic (2.74e-1)" "unprognostic (1.73e-2)" "unprognostic (1.74e-1)" "unprognostic (1.13e-3)" "unprognostic (2.13e-1)" "unprognostic (8.65e-2)" "unprognostic (5.17e-2)" "unprognostic (1.26e-2)" "unprognostic (1.18e-1)" "unprognostic (1.11e-7)" "unprognostic (3.73e-3)" "unprognostic (2.66e-1)" "unprognostic (9.49e-2)" "unprognostic (2.98e-2)" 1.2 2.0 1.1 2.3 1.2 0.6 0.6 1.8 1.5 1.0 0.1 1.0 0.3 0.8 0.5 0.6 0.9 1.1 1.0 1.1 0.9 0.8 0.9 1.2 2.2 1.2 1.2 1.1 1.1 0.5 1.5 0.5 1.2 1.4 1.2 1.4 0.4 0.6 0.2 0.3 0.8 0.8 0.8 1.7 0.7 4.0 1.1 3.7 0.4 0.2 1.9 1.5 0.8 1.2 0.1 0.0 0.4 1.2 2.7 14.1 0.2 4.1 0.9 0.2 0.3 0.2 0.1 0.2 0.7 42.0 0.2 0.1 0.1 0.1 0.3 0.7 0.1 0.1 0.4 1.6 17.3 0.3 0.2 6.2 0.3 2.1 0.3 1.3 81.2 1.5 0.1 0.5 67.5 0.0 0.7 0.4 0.3 0.1 0.6 2.0 0.1 0.6 0.6 0.1 0.1 0.6 0.3 0.2 0.9 1.3 0.0 0.7 0.6 0.1 0.1 0.4 0.2 0.9 1.4 0.3 0.2 7.7 4.4 0.0 0.1 0.1 0.5 0.0 0.3 0.5 0.2 0.4 0.3 0.5 0.4 0.4 0.7 1.7 0.0 1.2 0.4 2.8 1.1 1.2 1.8 1.5 1.1 0.9 1.2 1.2 1.2 0.8 1.1 1.2 0.2 0.0 0.5 8.5 0.8 0.8 0.3 0.4 0.6 0.4 0.2 0.0 1.5 1.5 0.1 1.8 0.0 0.2 2.2 0.9 0.0 0.1 5.8 0.2 0.4 1.0 0.0 0.8 3.6 0.0 0.2 3.7 0.0 0.1 0.0 37.0 0.0 1.2 0.5 0.0 5.2 0.0 0.0 0.6 2.3 2.2 0.3 26.4 1.8 0.0 8.2 1.3 2.1 2.5 4.0 0.3 0.1 1.9 0.4 0.4 0.0 0.2 0.8 0.5 0.0 0.6 3.7 0.3 0.2 0.0 0.6 0.0 2.4 0.7 0.1 0.1 TNFSF9 "4-1BB-L, 4-1BBL" ENSG00000125657 "TNF superfamily member 9" P41273 19 6531026-6535924 "Plasma proteins, Predicted intracellular proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 9.8;esophagus: 9.8;vagina: 9.5" "Cell type enhanced" "Detected in many" "B-cells: 57.5;dendritic cells: 51.6;Gastric mucus-secreting cells: 23.0;Macrophages: 22.5;T-cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 85.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA059857 Approved "Golgi apparatus" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus" "HPA059857: AB_2684144" "unprognostic (2.21e-1)" "unprognostic (1.84e-1)" "unprognostic (1.26e-1)" "unprognostic (7.67e-3)" "unprognostic (2.33e-1)" "unprognostic (1.35e-1)" "unprognostic (2.19e-2)" "unprognostic (2.78e-2)" "unprognostic (1.36e-1)" "unprognostic (2.93e-2)" "unprognostic (2.41e-3)" "unprognostic (4.88e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (5.10e-2)" "unprognostic (1.16e-1)" "unprognostic (1.62e-1)" "unprognostic (8.07e-3)" 1.8 0.6 3.5 1.0 3.0 3.7 0.8 3.7 7.6 9.8 2.3 1.2 0.3 0.3 0.3 9.8 1.1 1.0 0.6 3.9 3.3 0.9 0.4 4.9 1.1 3.6 2.9 0.5 0.3 0.5 0.3 0.9 3.4 0.3 1.8 0.3 1.5 0.1 0.7 1.4 1.2 0.4 3.1 2.2 0.6 3.3 3.1 0.5 0.4 0.3 0.7 0.7 9.5 6.3 10.7 13.4 0.2 4.8 2.5 6.0 0.4 1.5 4.8 3.6 17.1 0.3 18.0 11.3 6.8 3.0 0.0 19.2 5.4 2.3 0.9 0.0 2.6 1.8 18.4 4.4 0.4 0.3 85.8 1.0 10.1 20.1 5.5 2.6 0.6 1.6 10.9 0.2 1.3 1.5 0.9 1.8 1.8 0.7 9.5 1.2 0.0 2.8 22.9 0.4 0.0 0.0 29.8 1.7 5.0 0.6 1.2 16.4 6.2 0.0 9.6 26.0 0.0 26.9 10.2 20.9 10.2 5.9 5.9 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 3.5 3.0 3.7 7.6 3.9 3.3 3.6 2.9 3.4 3.1 3.1 6.3 11.3 0.0 4.5 0.0 57.5 2.7 0.3 4.3 6.2 0.2 4.0 3.8 8.1 0.0 1.6 0.0 0.0 0.1 51.6 4.3 0.0 0.3 0.1 5.7 3.9 6.8 14.2 0.0 2.2 0.2 0.0 12.6 23.0 9.2 8.9 0.6 1.8 0.0 4.5 0.0 2.5 3.4 2.0 1.9 15.9 0.0 0.0 22.5 3.6 0.0 1.6 0.8 0.0 1.5 2.9 0.8 4.9 0.0 17.2 0.9 0.2 0.1 0.9 0.2 0.0 2.5 7.5 0.1 0.4 12.7 1.3 0.1 31.5 0.9 5.7 0.3 TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.9" "Cell type enhanced" "Detected in many" "Horizontal cells: 99.3;Oligodendrocyte precursor cells: 245.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041954, HPA069561" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Vesicles "HPA041954: AB_10794164, HPA069561: " "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-3)" "prognostic unfavorable (8.96e-4)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (8.89e-3)" "unprognostic (1.13e-1)" "unprognostic (8.92e-3)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.82e-2)" "unprognostic (9.76e-2)" "unprognostic (1.44e-1)" "prognostic favorable (1.00e-4)" 14.2 10.0 77.1 24.7 64.1 72.2 15.0 40.0 102.9 18.0 11.8 18.5 9.4 13.8 11.1 19.1 17.1 10.5 18.4 75.6 51.4 7.7 10.5 14.1 30.0 77.5 59.8 13.4 12.1 6.1 36.4 12.7 70.1 21.1 6.3 9.3 26.3 11.8 54.8 62.3 16.1 9.2 45.5 27.0 19.7 12.0 57.0 16.0 10.0 16.7 20.1 19.4 19.3 60.6 93.4 16.3 15.4 13.4 15.3 11.5 80.0 17.7 16.7 11.7 9.4 15.6 79.3 25.9 55.1 24.2 17.4 34.1 14.9 22.2 3.5 61.8 15.4 22.0 36.2 10.4 7.9 13.5 10.2 7.8 30.7 11.7 17.9 26.7 13.3 9.2 11.3 30.6 9.4 67.1 5.3 39.7 12.3 24.6 29.1 13.8 15.6 26.0 7.2 51.2 16.2 16.5 9.5 37.6 21.3 11.3 71.4 11.9 18.9 19.1 13.0 11.4 48.6 70.8 9.2 17.0 22.1 38.0 15.4 1.4 1.2 0.3 0.9 1.5 0.4 1.3 0.8 0.4 0.5 2.5 0.5 0.5 2.7 0.4 1.4 1.5 0.1 0.7 77.1 64.1 40.0 102.9 75.6 51.4 77.5 59.8 70.1 45.5 57.0 60.6 9.3 6.4 7.7 44.4 14.6 6.9 8.1 6.0 4.6 30.6 13.0 12.6 16.1 7.2 8.9 0.0 50.1 13.4 11.0 18.0 1.9 4.0 1.0 4.1 5.4 11.1 6.1 12.8 42.7 5.3 3.3 4.6 14.3 4.1 1.3 4.5 11.7 19.2 8.1 99.3 45.3 2.3 6.1 16.0 11.7 1.2 6.5 13.7 5.4 20.6 16.2 5.9 21.6 245.3 25.1 29.5 9.6 6.4 10.7 8.2 0.9 1.6 7.6 20.3 0.0 4.8 5.7 6.4 11.2 11.0 10.5 4.2 12.5 1.7 6.4 19.0 TNN TNW ENSG00000120332 "Tenascin N" Q9UQP3 1 175067833-175148075 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 12.0;breast: 4.9" "Cell type enhanced" "Detected in some" "Adipocytes: 6.1;Fibroblasts: 7.5;Hepatic stellate cells: 2.5;Langerhans cells: 2.5;Smooth muscle cells: 10.4" "Cancer enhanced" "Detected in some" "breast cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.6;NB-4: 3.6;THP-1: 11.1;U-266/70: 2.7;U-937: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB010907, HPA026726, HPA026764" Uncertain "Secreted to extracellular matrix" NA NA 34000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "CAB010907: AB_477565, HPA026726: AB_10601771, HPA026764: AB_10601859" "unprognostic (1.16e-3)" "unprognostic (2.23e-2)" "unprognostic (1.35e-1)" "unprognostic (2.21e-2)" "unprognostic (1.34e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (3.55e-1)" "unprognostic (5.25e-3)" "unprognostic (1.01e-2)" "unprognostic (4.69e-1)" "unprognostic (5.07e-1)" "unprognostic (1.08e-3)" "unprognostic (1.76e-2)" "unprognostic (9.38e-3)" "unprognostic (1.89e-2)" "unprognostic (1.02e-2)" 12.0 0.2 0.0 0.1 0.1 0.0 4.9 0.0 0.1 0.1 0.1 0.3 0.8 0.0 0.0 0.1 0.0 1.7 0.3 0.2 0.0 0.4 1.3 0.4 0.1 0.0 0.1 0.0 0.3 0.8 2.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 3.1 0.4 0.4 0.1 0.4 0.4 0.1 0.1 0.1 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 11.1 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 6.1 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.7 0.0 0.1 7.5 0.0 0.1 0.0 0.0 2.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 10.4 0.4 1.4 0.0 1.8 0.1 0.1 0.0 0.0 0.1 TNR ENSG00000116147 "Tenascin R" Q92752 1 175315194-175743616 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 31.3;retina: 16.2" "Group enriched" "Detected in some" 6 "Horizontal cells: 580.5;Oligodendrocyte precursor cells: 2288.6" "Cancer enriched" "Detected in single" 46 "glioma: 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 1.9;U-937: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022343, HPA027134, HPA027150, HPA029859" Enhanced "Secreted in brain" NA NA 58000 "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "CAB022343: , HPA027134: AB_1851983, HPA027150: AB_1851985, HPA029859: AB_10600916" "unprognostic (1.04e-1)" "unprognostic (7.43e-2)" "unprognostic (3.11e-2)" "unprognostic (1.12e-3)" "unprognostic (2.38e-1)" "unprognostic (1.51e-2)" "unprognostic (9.66e-2)" "unprognostic (2.57e-2)" "unprognostic (5.79e-2)" "unprognostic (5.06e-2)" "unprognostic (3.03e-3)" "unprognostic (7.26e-4)" "unprognostic (4.48e-4)" "unprognostic (3.26e-3)" "unprognostic (3.83e-1)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" 0.0 1.4 30.7 0.2 24.3 0.1 0.0 15.2 26.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 31.3 27.7 0.0 0.4 0.5 0.2 23.3 16.4 0.0 0.4 0.0 2.7 0.0 20.3 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.4 0.0 20.8 0.2 0.3 0.4 18.2 0.1 0.1 0.0 0.3 0.0 0.0 30.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 30.7 24.3 15.2 26.3 31.3 27.7 23.3 16.4 20.3 20.8 18.2 30.5 0.0 0.0 0.0 20.2 2.4 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 226.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 580.5 179.6 0.0 0.0 0.0 0.3 1.6 0.0 0.1 0.0 3.7 0.0 1.8 0.0 2288.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 3.8 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 TNS1 "DKFZp586K0617, MXRA6, PPP1R155, TNS" ENSG00000079308 "Tensin 1" Q9HBL0 2 217799588-218033982 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Cardiomyocytes: 339.0;Leydig cells: 169.6;Peritubular cells: 504.0;Sertoli cells: 368.1;Smooth muscle cells: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 135.1;ASC TERT1: 74.1;fHDF/TERT166: 66.6;REH: 75.4;TIME: 63.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018774, HPA036089, HPA036090" Approved Enhanced "Focal adhesion sites" NA NA 47000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" "CAB018774: AB_2207032, HPA036089: AB_10796111, HPA036090: AB_10794322" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.13e-2)" "unprognostic (5.46e-2)" "unprognostic (2.63e-2)" "unprognostic (1.20e-3)" "unprognostic (7.34e-2)" "unprognostic (2.55e-2)" "unprognostic (1.28e-3)" "unprognostic (5.57e-2)" "unprognostic (9.74e-2)" "unprognostic (4.71e-3)" "unprognostic (5.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.49e-2)" "prognostic unfavorable (5.19e-4)" 248.2 60.3 51.6 42.9 98.0 42.3 100.9 71.7 45.5 99.5 45.1 373.4 23.4 253.7 44.3 117.8 136.2 80.4 170.4 34.0 53.4 74.6 39.6 117.2 11.5 82.3 79.2 110.4 55.2 33.2 15.4 54.5 106.4 126.1 41.7 7.7 52.9 225.0 171.6 47.8 78.9 178.0 72.2 70.1 115.2 23.5 80.9 21.5 65.8 207.2 7.5 228.4 82.6 82.9 0.3 0.4 8.9 0.1 135.1 74.1 0.8 22.9 7.8 1.3 0.9 10.0 0.1 0.0 13.1 66.6 1.5 1.7 1.4 1.3 0.7 9.4 0.8 19.8 5.7 2.6 9.8 0.1 2.3 35.2 0.0 24.4 0.2 43.6 32.2 0.1 0.6 2.6 18.8 4.4 0.1 1.4 0.9 0.2 0.4 75.4 16.8 1.0 4.8 0.2 2.1 10.1 3.9 9.7 2.0 6.1 3.1 8.5 63.2 16.6 29.5 17.5 4.9 1.1 0.1 0.1 9.8 2.7 1.2 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.0 0.8 51.6 98.0 71.7 45.5 34.0 53.4 82.3 79.2 106.4 72.2 80.9 82.9 93.3 173.1 85.9 29.7 1.1 16.2 48.6 29.5 42.1 4.8 7.2 21.2 339.0 38.6 27.5 14.7 0.0 8.7 0.5 0.1 7.9 36.1 2.2 3.0 29.5 76.6 0.0 143.1 3.9 19.1 1.5 52.4 1.1 3.8 30.4 8.8 71.7 38.5 13.0 42.1 5.3 0.0 6.1 15.3 19.3 11.9 169.6 16.7 10.6 32.8 1.3 14.1 0.0 15.6 52.0 17.0 0.0 504.0 0.4 12.1 0.0 26.1 22.3 1.3 368.1 29.7 183.5 1.1 1.9 5.7 11.8 1.9 4.1 20.7 0.2 17.3 TNXB "TNXB1, TNXB2, TNXBS, XB, XBS" ENSG00000168477 "Tenascin XB" P22105 6 32041153-32115334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 274.8" "Cell type enhanced" "Detected in many" "Adipocytes: 54.7;Fibroblasts: 318.4;Granulosa cells: 94.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 12.4;ASC TERT1: 20.1;U-2197: 15.8;U-87 MG: 8.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-3)" "unprognostic (9.57e-2)" "unprognostic (1.16e-1)" "unprognostic (9.51e-4)" "unprognostic (5.71e-2)" "unprognostic (2.30e-1)" "unprognostic (6.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.61e-2)" "unprognostic (2.17e-1)" "unprognostic (9.70e-2)" "unprognostic (3.13e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" 68.0 274.8 2.0 0.9 3.1 3.4 40.0 4.4 1.8 45.1 3.5 35.9 3.0 66.7 3.2 18.1 37.4 4.7 73.8 0.7 0.8 13.0 17.6 51.1 0.8 1.5 1.1 67.0 3.7 0.4 6.8 3.8 1.5 15.6 1.7 0.3 19.5 1.0 14.2 27.4 29.0 3.1 2.2 30.7 18.8 11.4 3.0 0.7 27.7 7.2 0.4 34.5 35.2 0.4 0.1 0.3 0.3 0.2 12.4 20.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.4 1.2 0.0 0.1 0.0 0.0 0.1 1.3 1.1 0.2 0.6 0.0 2.8 0.0 0.3 0.2 0.2 0.5 0.0 0.5 0.0 0.5 0.7 0.4 0.0 0.2 0.0 0.1 0.3 0.0 3.5 0.3 0.1 0.2 0.0 0.1 0.1 0.2 1.3 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.4 15.8 0.0 0.4 0.4 0.2 8.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 3.1 4.4 1.8 0.7 0.8 1.5 1.1 1.5 2.2 3.0 0.4 54.7 3.2 2.4 2.6 0.5 32.9 0.2 0.3 0.6 1.3 1.3 1.8 2.5 4.3 0.2 0.0 0.0 0.5 1.0 0.0 0.0 0.2 3.0 1.3 39.7 38.8 0.0 25.0 7.1 0.0 2.6 318.4 6.1 1.1 0.0 94.8 12.8 0.9 0.7 0.0 4.2 0.1 0.0 0.6 39.1 2.8 27.1 4.7 32.0 17.8 0.0 1.2 0.0 1.0 1.2 0.0 0.1 4.5 2.5 0.5 0.0 0.3 0.9 0.6 0.0 21.7 20.8 4.1 2.1 1.6 26.6 1.0 4.8 5.6 0.2 0.4 TOGARAM1 "crescerin, Crescerin-1, FAM179B, KIAA0423" ENSG00000198718 "TOG array regulator of axonemal microtubules 1" Q9Y4F4 14 44962190-45074431 "Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 65.7;Endometrial stromal cells: 28.6;Granulosa cells: 30.1;Respiratory ciliated cells: 38.6;Theca cells: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 4.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050849, HPA053559" Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA050849: AB_2681257, HPA053559: AB_2682190" "unprognostic (2.91e-1)" "unprognostic (4.07e-2)" "unprognostic (2.04e-2)" "unprognostic (1.05e-2)" "unprognostic (1.40e-1)" "unprognostic (1.17e-1)" "unprognostic (4.88e-2)" "unprognostic (2.67e-2)" "unprognostic (2.69e-1)" "unprognostic (1.21e-1)" "unprognostic (5.63e-2)" "unprognostic (6.49e-2)" "prognostic favorable (8.38e-4)" "unprognostic (1.62e-1)" "unprognostic (2.15e-1)" "unprognostic (3.02e-2)" "unprognostic (1.60e-1)" 4.5 6.6 9.6 2.9 13.4 3.9 5.2 10.1 13.0 6.7 9.6 4.5 2.7 6.0 5.2 4.6 10.4 4.7 8.3 11.2 8.9 7.9 4.6 3.9 3.9 7.2 8.0 7.6 6.3 8.5 7.1 5.8 8.7 5.5 3.7 16.8 4.8 6.4 12.4 4.2 3.8 5.4 7.5 4.3 4.3 6.5 9.3 8.4 9.0 12.1 3.9 5.4 4.3 19.9 3.5 5.7 5.3 1.4 12.2 14.2 3.8 4.9 10.4 9.1 10.8 2.3 3.7 3.3 5.6 7.9 4.9 6.4 9.8 3.3 10.0 3.0 3.6 2.7 2.8 2.7 8.6 4.6 2.7 8.3 5.6 5.2 8.8 10.8 7.4 1.8 1.9 3.7 9.2 5.0 5.9 2.5 1.8 5.2 4.3 2.9 12.9 2.2 8.6 12.0 5.5 2.1 5.8 8.4 9.1 5.5 6.2 3.6 5.5 6.1 4.9 7.8 3.7 3.8 3.0 3.7 3.5 0.9 5.2 4.8 0.4 1.0 0.4 0.4 0.5 0.4 0.6 0.4 0.6 0.6 0.5 0.3 0.0 0.8 0.4 0.7 0.6 0.3 9.6 13.4 10.1 13.0 11.2 8.9 7.2 8.0 8.7 7.5 9.3 19.9 15.8 16.0 14.9 0.0 4.5 0.0 0.0 0.0 0.0 0.0 15.2 10.9 0.0 0.0 20.4 16.5 0.0 11.9 13.2 0.0 1.9 10.2 0.0 65.7 28.6 6.6 0.0 0.0 0.0 5.6 8.1 8.8 0.0 16.0 10.1 30.1 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 6.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 3.8 0.0 0.0 10.4 38.6 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 9.9 6.3 34.4 0.0 0.0 TOMM40 "C19orf1, D19S1177E, PER-EC1, PEREC1, TOM40" ENSG00000130204 "Translocase of outer mitochondrial membrane 40" O96008 19 44890569-44903689 "Predicted intracellular proteins, Transporters" "Ion transport, Protein transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036231, HPA036232" Supported Enhanced Mitochondria,Cytosol NA NA 45000 "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA036231: AB_2675010, HPA036232: AB_2675011" "unprognostic (2.14e-1)" "unprognostic (9.58e-3)" "unprognostic (1.66e-1)" "unprognostic (6.75e-3)" "unprognostic (2.37e-1)" "unprognostic (2.17e-2)" "unprognostic (1.13e-3)" "unprognostic (1.13e-2)" "unprognostic (7.84e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (5.86e-3)" "unprognostic (5.30e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.87e-1)" 34.6 59.7 31.3 25.1 30.1 32.9 29.0 33.6 37.2 25.2 28.0 34.7 28.4 25.0 14.1 51.8 25.3 10.8 46.1 30.7 33.5 33.5 50.8 28.4 23.6 32.6 33.5 24.9 26.6 31.4 25.3 20.0 33.6 24.7 23.0 18.0 24.1 17.4 64.0 34.4 26.1 16.4 30.2 26.4 29.3 22.0 35.0 25.2 22.3 34.4 22.6 29.9 29.5 32.2 147.6 244.6 87.6 121.3 32.2 28.4 110.3 103.3 57.1 192.1 136.6 268.8 99.5 215.3 107.7 68.8 108.7 155.2 228.9 149.1 87.0 84.0 206.1 145.3 93.5 214.7 68.0 187.6 125.1 45.2 83.4 149.3 94.1 36.0 67.3 102.4 232.6 73.3 76.4 184.2 205.4 137.1 153.6 209.6 149.1 206.1 99.2 125.3 89.6 201.8 135.2 86.4 109.9 229.4 75.2 48.4 77.1 188.2 55.9 132.0 133.6 93.1 273.7 78.3 176.0 212.9 98.2 197.0 142.1 0.7 3.6 3.7 2.8 4.6 3.2 5.8 2.8 4.1 4.6 2.4 4.9 5.4 0.7 3.2 4.3 4.6 3.5 1.4 31.3 30.1 33.6 37.2 30.7 33.5 32.6 33.5 33.6 30.2 35.0 32.2 26.2 16.0 7.3 8.8 34.9 87.4 73.7 17.1 35.9 68.2 32.7 30.9 15.7 25.8 14.3 31.3 29.2 104.5 28.9 78.8 39.2 48.1 11.3 22.7 41.0 31.0 29.3 52.4 11.3 38.6 169.9 38.6 40.2 29.5 19.1 57.8 12.5 24.2 100.1 70.7 16.9 59.4 28.5 21.0 44.9 7.2 26.8 35.0 39.2 4.7 31.9 46.6 27.8 5.5 12.8 53.6 32.4 24.5 47.9 139.0 34.5 39.5 4.9 60.2 19.7 49.1 47.8 46.2 64.5 60.5 89.4 72.9 26.7 105.9 132.1 75.5 TOMM7 Tom7 ENSG00000196683 "Translocase of outer mitochondrial membrane 7" Q9P0U1 7 22812628-22822852 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 32: Non-specific - Translation" "unprognostic (6.69e-2)" "unprognostic (1.93e-1)" "unprognostic (4.91e-2)" "unprognostic (2.25e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (6.30e-4)" "unprognostic (2.25e-2)" "unprognostic (7.63e-2)" "unprognostic (1.52e-1)" "unprognostic (6.36e-2)" "unprognostic (2.49e-3)" "unprognostic (1.36e-1)" "unprognostic (1.75e-1)" "unprognostic (3.69e-3)" "unprognostic (2.08e-1)" "unprognostic (3.86e-2)" "unprognostic (1.01e-2)" 573.8 563.3 949.6 275.4 981.1 502.7 881.7 958.2 1282.5 678.2 985.2 739.2 356.5 495.5 537.9 428.7 587.3 242.1 701.6 934.9 962.7 495.7 491.2 443.6 496.2 956.1 949.0 973.9 682.7 523.2 539.2 248.2 953.4 481.8 421.2 419.1 527.3 508.3 1753.2 585.5 466.8 408.5 979.2 484.0 554.7 223.6 972.7 428.0 390.2 1299.3 674.7 524.7 524.5 979.0 712.5 403.3 257.7 530.0 951.1 1090.9 303.8 501.7 813.4 382.9 337.6 295.1 454.1 556.3 592.0 704.4 1148.1 457.9 672.4 540.6 415.7 303.3 695.0 269.6 942.9 386.3 811.1 638.0 289.4 1368.6 1222.6 575.7 862.1 1434.9 637.3 418.4 951.4 470.7 696.7 572.4 335.1 899.0 900.4 1002.6 960.5 282.0 302.0 782.7 353.7 367.6 241.7 416.3 367.6 886.3 1339.5 1009.6 658.7 1079.9 405.1 292.7 469.8 533.7 578.4 969.8 1141.0 783.5 389.4 658.3 1061.3 264.1 588.8 556.9 665.4 489.8 831.8 1233.9 1126.6 806.9 566.8 1053.9 1488.5 1059.0 199.4 567.6 525.1 868.7 919.5 1759.4 949.6 981.1 958.2 1282.5 934.9 962.7 956.1 949.0 953.4 979.2 972.7 979.0 483.9 259.6 350.4 25.1 883.6 886.1 805.5 698.9 570.8 279.7 998.5 1129.9 1223.2 622.0 372.1 349.4 66.7 477.2 670.5 558.3 1328.5 434.1 385.9 473.8 382.6 503.8 531.4 351.7 13.3 935.5 735.0 535.1 270.1 386.9 504.1 461.8 745.0 1228.2 699.6 151.4 12.7 1021.7 280.8 934.6 818.0 344.0 993.2 536.6 788.0 12.2 781.9 1059.7 784.8 8.5 19.5 534.9 823.7 759.8 360.8 828.6 1052.8 1386.2 362.6 311.9 486.4 996.5 557.8 448.0 204.1 691.9 926.6 406.1 811.4 292.2 879.5 820.9 TOR1A "DQ2, DYT1" ENSG00000136827 "Torsin family 1 member A" O14656 9 129812942-129824244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012473, HPA051195" Approved Supported "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 20000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Vesicles" "CAB012473: AB_2240792, HPA051195: AB_2681382" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.95e-1)" "unprognostic (1.86e-3)" "unprognostic (3.67e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.10e-2)" "unprognostic (1.41e-1)" "unprognostic (4.10e-2)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (3.39e-1)" "unprognostic (1.91e-1)" "unprognostic (1.77e-1)" "unprognostic (1.99e-1)" 21.2 24.2 14.3 20.7 14.8 34.5 19.6 14.7 17.7 18.6 14.2 20.7 16.6 20.3 19.9 14.3 17.2 20.6 16.8 15.7 15.9 20.5 35.9 19.4 22.9 13.6 14.0 17.2 19.5 19.4 14.3 23.5 14.0 21.3 22.3 9.8 17.0 23.1 16.4 17.8 18.8 25.4 14.1 18.8 18.1 9.2 15.4 26.3 23.8 14.9 19.0 28.6 15.6 14.8 33.7 49.5 35.9 41.5 53.1 51.3 47.4 76.7 94.5 67.0 57.2 32.3 48.2 41.0 44.0 99.7 46.0 77.2 34.7 50.8 54.7 65.7 32.9 36.9 49.8 32.3 66.9 82.1 65.5 69.8 50.7 63.5 45.6 61.5 73.2 65.3 66.5 32.3 74.6 84.3 58.9 79.3 53.8 39.2 55.6 30.5 56.5 41.9 54.9 42.4 27.0 47.6 79.3 30.7 43.3 40.1 61.6 63.4 65.1 66.1 37.7 49.6 59.6 36.6 87.0 37.7 49.0 46.9 54.3 95.5 72.8 141.3 57.4 68.5 48.1 45.5 48.4 52.1 61.4 33.5 40.9 42.4 72.7 68.6 58.3 56.5 59.1 78.9 14.3 14.8 14.7 17.7 15.7 15.9 13.6 14.0 14.0 14.1 15.4 14.8 25.0 9.6 11.8 5.5 17.5 17.6 16.6 39.5 12.0 11.2 16.5 15.9 9.9 18.6 24.4 14.7 2.1 47.9 39.3 18.7 15.6 42.1 0.7 12.5 18.8 24.2 19.2 30.5 6.3 49.9 65.7 25.0 13.7 15.0 22.2 23.4 16.1 22.7 45.2 21.9 6.4 17.8 26.4 19.1 22.4 1.3 12.8 27.9 14.2 3.7 47.6 18.5 35.0 9.5 6.6 40.1 18.9 15.4 23.7 24.7 21.0 17.0 14.9 9.2 32.9 15.2 24.3 7.3 10.1 9.3 18.5 53.4 25.5 23.4 15.4 19.6 TOR1B "DQ1, MGC4386" ENSG00000136816 "Torsin family 1 member B" O14657 9 129803157-129811281 "Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013403, HPA013697, CAB022709" Approved Uncertain "Nuclear speckles,Cytosol" "Intracellular and membrane" NA NA 140000 "Cluster 5: Granulocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" Cytosol "CAB022709: , HPA013403: AB_1858195, HPA013697: AB_1858196" "unprognostic (2.91e-3)" "unprognostic (1.73e-1)" "unprognostic (1.14e-1)" "unprognostic (8.55e-2)" "unprognostic (3.23e-1)" "unprognostic (3.72e-2)" "unprognostic (1.75e-1)" "unprognostic (5.73e-3)" "unprognostic (1.95e-1)" "unprognostic (7.47e-2)" "unprognostic (1.40e-1)" "unprognostic (2.13e-2)" "unprognostic (2.07e-3)" "unprognostic (4.09e-2)" "unprognostic (1.23e-1)" "unprognostic (5.40e-3)" "unprognostic (1.69e-3)" 11.1 10.0 8.6 13.1 8.4 14.3 8.7 12.0 8.7 8.4 9.5 20.3 11.3 9.1 7.0 10.3 7.7 13.3 8.9 8.2 9.2 8.6 18.5 11.7 11.0 8.8 8.6 7.5 12.6 11.7 7.3 14.2 8.7 11.0 22.6 5.9 10.3 9.2 10.6 11.8 14.1 12.6 8.6 9.3 11.9 10.2 9.5 10.7 10.7 9.9 9.4 15.8 8.5 8.4 11.7 26.5 10.9 29.0 53.2 39.4 25.0 40.8 26.7 27.6 27.2 22.0 26.1 8.3 25.2 40.7 43.0 46.4 11.9 16.9 28.2 30.4 12.3 7.2 21.5 15.8 22.8 13.8 31.1 22.6 29.3 39.6 19.4 20.4 24.9 21.5 25.6 18.8 26.2 32.9 19.2 21.8 22.9 54.8 20.1 7.8 18.9 25.3 21.3 12.1 15.0 17.2 26.0 30.4 16.6 19.5 43.7 13.5 22.7 51.9 24.5 62.4 35.7 13.6 53.9 7.0 28.6 17.9 36.0 8.7 13.3 20.2 12.6 16.0 13.0 4.0 10.0 11.2 6.9 4.7 7.3 7.3 16.4 8.8 10.1 4.2 10.5 9.9 8.6 8.4 12.0 8.7 8.2 9.2 8.8 8.6 8.7 8.6 9.5 8.4 9.5 9.6 2.4 6.5 11.7 6.5 5.9 7.3 12.5 2.7 6.9 5.6 5.5 5.7 6.1 5.5 4.2 10.8 16.1 15.3 0.0 9.7 13.3 5.0 6.7 8.2 19.2 3.4 13.9 13.7 17.7 10.5 17.9 5.7 4.5 4.0 9.7 13.3 12.0 6.7 15.6 16.2 4.1 5.4 5.0 15.1 4.4 12.1 3.6 4.7 12.3 4.7 16.5 14.6 10.5 12.6 6.7 5.7 14.5 10.1 10.7 3.7 9.4 2.7 19.7 6.8 13.0 22.7 5.4 10.4 5.4 15.2 12.2 4.6 10.5 11.2 TOR2A "FLJ14771, TORP1" ENSG00000160404 "Torsin family 2 member A" "Q5JU69, Q8N2E6" 9 127731524-127735313 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 69.1;Theca cells: 114.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071229 Approved Uncertain "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum, Plasma membrane" "HPA071229: AB_2732175" "unprognostic (1.67e-1)" "unprognostic (9.19e-3)" "unprognostic (1.47e-1)" "unprognostic (1.27e-3)" "unprognostic (3.04e-2)" "unprognostic (6.97e-2)" "unprognostic (2.43e-3)" "unprognostic (4.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.33e-1)" "unprognostic (6.51e-3)" "unprognostic (1.05e-2)" "unprognostic (6.98e-2)" "prognostic favorable (7.51e-4)" "unprognostic (1.72e-1)" "unprognostic (3.27e-1)" "unprognostic (2.82e-2)" 6.8 10.7 9.6 6.8 9.3 26.9 6.7 9.4 13.2 7.9 9.5 12.2 11.2 6.7 3.4 11.4 7.0 4.9 5.4 9.2 9.1 10.2 14.0 8.7 7.7 9.4 9.2 8.2 13.6 3.1 10.0 7.9 8.9 8.1 5.4 2.9 8.7 3.6 3.3 9.5 12.8 2.7 8.6 20.8 11.8 20.4 9.7 8.4 8.7 2.2 4.5 7.1 7.1 9.1 7.4 11.5 9.7 12.2 4.7 4.6 13.0 5.1 6.3 8.0 6.3 7.9 12.6 13.6 7.5 4.4 6.0 23.2 3.0 6.4 2.2 21.1 11.0 5.2 10.6 9.7 7.7 11.0 27.0 7.4 11.8 7.4 3.9 4.0 11.5 16.2 16.2 37.3 4.7 43.4 14.3 34.7 8.7 24.0 9.9 23.4 4.5 30.9 8.3 6.9 21.0 8.3 4.7 16.6 5.3 5.3 37.0 21.4 7.2 5.2 6.0 9.1 6.0 23.4 21.8 5.6 6.4 17.8 5.0 26.5 68.5 96.5 32.8 80.2 26.1 12.1 18.9 32.5 71.6 18.0 14.0 25.2 44.0 26.9 78.3 16.2 32.2 41.5 9.6 9.3 9.4 13.2 9.2 9.1 9.4 9.2 8.9 8.6 9.7 9.1 5.3 3.2 5.1 6.2 12.4 1.5 4.4 16.6 1.2 13.7 8.7 5.8 0.6 15.7 9.6 3.7 0.0 37.9 16.0 26.4 1.9 19.1 69.1 7.0 5.7 8.5 22.8 34.1 5.5 27.4 38.9 10.1 8.2 10.8 5.7 11.7 15.0 7.5 56.9 8.4 4.6 20.4 20.3 33.9 8.3 10.7 11.5 26.2 3.6 2.8 25.2 11.7 30.9 6.0 3.7 15.5 28.7 11.3 21.1 6.0 33.9 8.7 7.7 14.6 0.0 2.5 4.2 30.6 10.9 7.5 1.4 51.9 15.0 114.6 18.3 4.9 TOR3A "ADIR, ADIR2, FLJ22345" ENSG00000186283 "Torsin family 3 member A" Q9H497 1 179082070-179098023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 112.6;Plasma cells: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 281.7;U-266/84: 322.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028766 Approved "Intracellular and membrane" NA Yes 24000 "Cluster 19: B-cells - Humoral immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA028766: AB_10602251" "unprognostic (5.55e-2)" "unprognostic (6.52e-2)" "unprognostic (2.80e-1)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (3.90e-1)" "unprognostic (8.82e-3)" "unprognostic (6.47e-2)" "unprognostic (2.02e-2)" "unprognostic (4.87e-2)" "unprognostic (2.27e-1)" "unprognostic (3.99e-1)" "prognostic unfavorable (4.78e-8)" "unprognostic (4.26e-2)" "unprognostic (2.27e-1)" "unprognostic (3.58e-1)" "unprognostic (1.35e-1)" 17.0 15.5 16.9 30.8 17.9 39.7 19.5 16.4 18.6 16.7 19.3 26.1 23.3 16.1 12.8 15.8 17.8 18.1 12.8 17.2 19.4 17.0 27.8 20.4 46.4 18.3 17.2 14.8 23.4 22.5 16.9 15.3 17.2 17.9 26.0 9.5 23.9 17.0 24.4 17.8 23.1 18.8 17.6 37.4 26.5 4.3 19.9 26.7 18.6 13.9 44.8 23.3 13.5 19.3 56.8 65.5 18.6 52.6 38.2 29.9 57.1 41.4 50.0 48.0 34.8 29.8 86.4 90.0 70.2 41.1 28.9 68.5 53.7 34.6 25.3 70.8 49.4 98.3 38.5 45.9 62.9 109.6 80.6 33.1 31.0 35.3 31.9 19.2 35.5 34.8 123.9 164.3 33.8 121.4 66.3 60.5 38.6 68.0 36.4 49.4 33.9 88.4 30.5 76.8 37.8 49.3 61.9 96.9 25.5 32.5 71.5 80.1 22.0 36.2 25.6 59.9 54.3 281.7 322.8 77.4 25.1 77.3 26.5 5.2 71.3 19.3 33.6 56.5 41.4 97.8 29.9 37.7 85.7 73.1 22.7 27.6 14.1 31.5 59.4 93.1 43.3 53.3 16.9 17.9 16.4 18.6 17.2 19.4 18.3 17.2 17.2 17.6 19.9 19.3 24.8 3.2 11.7 4.9 65.2 17.0 14.0 19.2 10.8 3.7 14.8 11.3 11.5 25.8 11.1 11.0 10.4 30.1 32.5 18.6 3.9 34.0 1.1 10.6 16.8 19.3 14.4 18.3 4.4 44.5 57.5 19.8 20.9 11.1 10.8 14.3 13.9 10.7 57.4 0.0 4.6 18.9 32.6 22.0 112.6 1.1 17.1 36.4 16.0 5.6 50.6 17.1 16.5 3.0 4.0 18.9 17.9 18.8 153.7 19.5 15.1 10.3 13.4 9.6 6.6 18.9 17.3 0.8 5.3 12.7 15.8 10.9 24.8 21.2 27.0 12.3 TOX2 "C20orf100, dJ1108D11.2, GCX-1" ENSG00000124191 "TOX high mobility group box family member 2" Q96NM4 20 43914852-44069616 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 50.2" "Cell type enhanced" "Detected in many" "Early spermatids: 22.3;Excitatory neurons: 20.5;Hepatic stellate cells: 34.2;Inhibitory neurons: 76.9;Oligodendrocyte precursor cells: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 92.0;U-266/70: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049900, HPA058396" Approved Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA049900: AB_2680942, HPA058396: AB_2683704" "unprognostic (2.15e-2)" "unprognostic (1.82e-2)" "unprognostic (8.97e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (7.53e-3)" "unprognostic (6.29e-2)" "unprognostic (1.66e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (7.45e-8)" "unprognostic (1.60e-1)" "unprognostic (2.00e-1)" "unprognostic (7.60e-2)" "unprognostic (3.12e-1)" 10.0 4.0 11.2 6.2 8.2 1.8 6.8 4.9 18.4 10.2 2.3 7.6 1.3 6.2 1.1 12.8 3.6 2.9 3.6 8.3 35.7 5.1 5.2 36.4 13.3 12.3 18.8 3.1 2.0 10.1 24.6 2.6 15.9 16.7 2.4 1.9 3.8 2.7 1.5 5.1 10.2 1.6 5.8 5.7 9.7 20.8 25.9 50.2 7.4 6.4 8.1 17.6 8.9 10.6 9.9 12.5 4.9 0.9 4.7 13.3 0.1 11.5 5.3 8.1 8.9 0.0 4.0 0.0 16.8 16.6 35.2 5.1 3.2 0.3 8.4 15.5 2.7 0.0 1.1 0.0 92.0 0.1 19.4 31.0 14.0 27.0 1.6 25.8 9.4 9.5 0.0 14.5 4.6 11.3 3.2 4.5 3.0 0.3 42.2 0.0 10.1 15.4 0.0 1.2 4.3 35.8 2.4 0.0 18.0 0.5 0.0 9.2 11.3 0.0 7.5 0.3 0.1 57.4 13.5 9.0 16.9 0.1 27.0 0.0 0.2 6.5 0.0 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.7 1.1 0.0 2.6 1.2 0.1 11.2 8.2 4.9 18.4 8.3 35.7 12.3 18.8 15.9 5.8 25.9 10.6 8.0 0.0 0.6 3.9 3.4 1.0 1.0 0.7 0.0 0.8 0.2 0.1 0.8 1.5 0.1 0.0 0.0 0.0 7.3 0.3 0.0 0.1 22.3 0.3 8.9 8.9 0.0 0.0 20.5 0.2 0.1 6.7 1.5 0.3 0.0 10.7 34.2 0.5 1.5 3.3 76.9 0.6 0.0 2.9 3.6 17.3 1.8 1.2 1.8 3.7 0.2 4.6 1.0 45.2 0.5 0.1 2.2 0.7 12.1 0.5 0.0 0.1 0.0 0.1 0.0 0.4 8.7 1.3 1.8 0.2 1.3 0.3 10.5 0.1 1.8 0.3 TP53BP1 "53BP1, p202, TDRD30" ENSG00000067369 "Tumor protein p53 binding protein 1" Q12888 15 43403061-43510728 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004083, HPA008788, HPA022133, CAB079980" Supported Supported "Nucleoplasm,Nuclear bodies,Mitotic chromosome,Vesicles" Yes No "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "Nucleoplasm, Mitotic chromosome, Vesicles" "CAB004083: AB_10694558, CAB079980: , HPA008788: AB_1078070, HPA022133: AB_1844382" "unprognostic (2.12e-1)" "unprognostic (7.96e-2)" "unprognostic (1.11e-1)" "unprognostic (1.85e-2)" "unprognostic (4.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.03e-2)" "unprognostic (3.96e-1)" "unprognostic (2.17e-1)" "unprognostic (2.81e-2)" "unprognostic (3.34e-2)" "unprognostic (4.07e-1)" "unprognostic (8.06e-2)" "unprognostic (9.11e-2)" "unprognostic (1.52e-1)" "unprognostic (6.99e-2)" "unprognostic (3.38e-2)" 6.9 11.5 17.4 10.1 16.6 11.5 10.7 19.9 14.5 17.7 21.5 9.7 6.4 16.0 15.9 6.1 14.7 10.7 8.8 15.4 26.3 9.1 4.1 8.3 8.6 13.5 16.7 16.8 7.4 22.3 24.1 12.2 15.7 12.1 10.2 22.0 10.1 12.8 7.2 9.2 6.4 16.3 9.6 8.7 7.6 21.6 23.0 15.3 17.9 11.0 12.6 11.2 8.7 12.1 13.5 22.3 63.8 40.1 25.8 31.9 15.8 22.8 33.8 31.0 39.1 19.4 15.8 14.5 19.2 39.0 66.9 32.4 46.3 27.5 36.8 38.9 15.8 27.1 40.1 11.7 16.8 30.2 37.4 24.9 19.0 41.8 31.2 51.7 37.4 24.2 26.9 12.3 36.5 9.6 23.7 14.1 41.1 24.2 13.9 25.1 23.9 9.3 22.9 31.8 57.3 26.8 33.8 14.3 8.5 48.6 29.9 16.9 27.5 33.7 22.3 27.0 20.5 9.8 22.4 33.0 27.6 14.6 17.5 1.4 0.5 1.0 1.6 0.7 1.3 1.9 1.6 1.6 1.2 1.8 1.8 1.6 0.6 0.9 0.5 1.3 1.4 0.7 17.4 16.6 19.9 14.5 15.4 26.3 13.5 16.7 15.7 9.6 23.0 12.1 11.5 22.4 22.3 53.2 17.8 6.4 10.2 10.0 13.6 32.4 17.4 13.2 14.9 5.7 20.8 29.5 47.9 13.4 11.1 7.4 9.8 14.5 38.8 47.0 44.8 16.8 41.9 8.4 66.2 7.1 11.2 23.9 14.8 26.8 26.6 47.0 15.0 3.3 10.8 47.1 81.9 15.7 12.2 3.8 6.9 17.8 23.6 9.3 1.8 17.8 4.0 11.9 7.2 62.8 50.4 7.5 5.8 17.7 17.1 11.0 2.6 8.8 60.7 51.7 13.1 35.2 20.5 33.1 36.2 14.7 5.3 18.5 17.0 29.9 13.4 8.9 TP53BP2 "53BP2, ASPP2, PPP1R13A" ENSG00000143514 "Tumor protein p53 binding protein 2" Q13625 1 223779893-223845954 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 152.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021603, HPA050429" Supported Enhanced "Cell Junctions,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Cell Junctions, Cytosol" "HPA021603: AB_1844384, HPA050429: AB_2681124" "unprognostic (1.29e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-1)" "unprognostic (1.38e-3)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (7.65e-2)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (1.48e-2)" "unprognostic (7.37e-2)" "unprognostic (2.67e-1)" "unprognostic (7.99e-2)" "unprognostic (5.08e-2)" "unprognostic (1.24e-1)" "unprognostic (2.81e-2)" "unprognostic (1.83e-1)" 11.7 8.5 35.3 12.2 37.2 49.8 9.5 34.7 39.4 11.4 35.6 9.9 8.5 12.6 10.0 16.8 10.1 18.4 12.2 33.0 34.4 9.7 14.9 18.4 12.8 34.9 35.8 13.8 12.0 15.8 7.1 8.9 33.2 8.9 9.9 38.0 12.4 8.1 13.0 13.0 10.0 11.1 33.5 9.3 12.4 11.2 37.4 15.8 20.7 11.2 13.1 16.6 11.7 35.8 32.8 16.2 42.9 27.3 15.0 14.5 27.3 20.6 29.3 29.4 25.1 33.6 19.2 0.0 17.5 17.3 21.3 21.9 33.9 12.3 39.3 62.9 33.2 43.1 15.2 11.5 30.3 36.0 28.9 17.5 13.3 27.2 27.7 22.1 17.7 23.6 55.7 31.7 24.8 9.5 27.5 22.2 37.0 19.7 15.6 36.0 44.7 3.7 26.5 20.4 36.9 47.6 22.8 27.9 29.9 27.9 15.8 48.6 20.7 30.0 21.1 32.7 39.2 15.4 17.3 26.4 18.1 23.9 35.0 4.8 1.2 0.8 0.9 1.3 1.2 0.9 1.1 1.8 1.3 0.8 1.1 0.8 1.4 3.3 1.0 0.8 0.8 1.0 35.3 37.2 34.7 39.4 33.0 34.4 34.9 35.8 33.2 33.5 37.4 35.8 18.2 48.1 22.7 76.4 23.7 17.2 41.6 7.2 21.1 8.1 12.6 8.0 20.3 18.6 28.3 7.3 52.1 10.3 24.2 13.0 1.9 20.4 1.1 45.0 42.2 19.1 14.9 54.3 1.7 10.7 5.9 22.6 21.9 152.0 48.8 14.1 8.6 10.7 9.8 0.0 5.3 8.7 14.2 14.1 44.4 2.4 10.5 41.7 8.8 23.4 9.6 10.0 7.2 27.2 29.0 21.4 7.3 8.6 27.4 30.9 6.7 5.5 15.6 45.5 0.0 41.2 26.3 12.3 20.1 21.1 11.6 4.8 38.8 31.4 10.2 40.6 TP53I13 DSCP1 ENSG00000167543 "Tumor protein p53 inducible protein 13" Q8NBR0 17 29566052-29573157 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 110.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.93e-1)" "unprognostic (4.90e-2)" "unprognostic (2.50e-3)" "unprognostic (9.31e-3)" "unprognostic (4.94e-3)" "unprognostic (1.05e-2)" "unprognostic (2.17e-1)" "unprognostic (2.41e-1)" "unprognostic (1.85e-1)" "unprognostic (5.47e-2)" "prognostic favorable (3.13e-5)" "unprognostic (1.95e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (2.92e-2)" 71.2 34.7 19.5 30.3 20.4 37.4 58.5 18.6 28.3 41.8 26.2 50.0 45.1 36.8 5.6 31.1 35.5 19.5 53.1 17.7 18.7 68.2 111.3 50.2 42.4 23.6 21.3 33.1 47.2 15.7 91.8 13.5 21.8 43.1 8.9 1.5 35.6 14.4 30.1 29.0 79.1 10.3 19.6 78.1 48.1 60.5 21.0 11.7 58.0 11.0 16.2 41.9 38.6 22.4 27.9 73.9 22.2 64.0 37.0 25.4 41.0 45.6 20.5 27.2 29.2 31.3 11.1 19.3 49.1 27.9 38.5 66.8 10.4 13.4 3.9 84.2 41.3 11.8 85.0 29.0 33.0 19.7 34.5 21.9 19.0 23.9 8.4 18.5 16.6 39.6 17.3 34.8 12.1 45.4 48.7 79.1 9.8 32.4 28.1 91.0 53.4 69.0 24.9 17.8 10.0 32.5 56.9 21.0 22.4 8.1 60.7 81.5 19.1 26.9 40.6 28.9 36.2 71.7 33.9 15.8 47.5 11.9 32.4 52.6 11.2 20.8 26.5 14.5 26.4 24.1 25.4 20.1 26.0 23.4 19.8 17.9 0.9 28.8 9.7 110.9 25.0 13.6 19.5 20.4 18.6 28.3 17.7 18.7 23.6 21.3 21.8 19.6 21.0 22.4 19.5 0.0 3.0 16.3 31.2 13.8 42.4 48.1 25.6 0.8 28.2 38.9 28.1 12.8 23.2 40.5 6.2 50.8 47.7 30.2 7.9 33.9 17.9 19.7 32.4 14.1 19.9 9.0 5.6 28.7 40.0 47.5 30.1 28.1 15.9 33.9 13.2 22.1 27.4 6.7 4.0 28.6 24.4 10.7 31.2 8.4 34.5 28.9 30.2 18.7 23.1 20.0 12.3 3.5 5.6 27.4 31.7 18.8 31.8 30.6 51.9 17.7 16.2 9.0 19.7 31.9 26.0 87.8 33.4 13.9 7.4 22.6 30.4 23.9 27.1 37.6 TPCN1 "FLJ20612, KIAA1169, TPC1" ENSG00000186815 "Two pore segment channel 1" Q9ULQ1 12 113221050-113298585 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 174.3;Microglial cells: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 148.6;hTERT-RPE1: 121.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039757 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA039757: AB_10795156" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.10e-2)" "unprognostic (1.22e-1)" "unprognostic (7.34e-2)" "unprognostic (3.07e-2)" "unprognostic (1.32e-3)" "unprognostic (4.53e-1)" "unprognostic (5.34e-2)" "unprognostic (1.48e-2)" "unprognostic (1.74e-3)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" "unprognostic (2.23e-1)" "unprognostic (9.08e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-3)" 27.7 48.8 37.7 18.2 54.3 12.5 29.1 70.2 40.5 36.9 48.5 30.4 19.4 30.6 19.3 38.4 35.5 21.7 68.0 34.7 33.4 50.9 27.8 29.5 17.0 43.5 48.3 41.5 52.0 30.8 37.9 18.8 46.6 28.7 19.5 11.5 36.1 27.3 36.7 22.2 31.4 18.6 35.4 28.6 19.1 14.5 44.0 8.5 55.5 24.8 18.2 25.3 26.4 45.9 15.3 45.0 5.1 6.5 38.5 43.3 14.9 21.2 148.6 10.9 13.1 33.5 50.7 34.5 30.9 21.6 35.7 18.8 11.9 37.6 14.7 4.1 9.2 12.9 23.5 18.7 49.9 4.5 28.1 41.5 18.6 21.3 37.2 121.7 16.9 9.8 15.0 11.9 13.5 18.3 1.3 68.3 8.4 18.6 22.3 2.5 6.2 67.3 34.9 54.4 6.5 9.8 17.0 43.2 17.1 10.3 13.9 41.4 7.1 16.0 7.8 22.3 13.3 20.0 13.1 29.6 47.2 10.9 12.3 6.9 14.6 1.3 1.8 2.4 2.0 3.4 2.4 2.3 9.9 5.2 3.3 2.1 0.5 8.5 0.3 5.0 1.2 4.7 37.7 54.3 70.2 40.5 34.7 33.4 43.5 48.3 46.6 35.4 44.0 45.9 8.3 9.6 19.6 174.3 9.0 4.6 6.0 15.4 2.8 19.6 17.0 11.2 34.4 12.8 24.4 27.6 16.7 7.2 3.1 35.9 1.9 13.2 13.2 15.0 21.8 8.1 28.8 9.0 24.5 18.7 3.2 20.2 23.0 19.1 31.1 7.7 15.7 18.3 21.5 50.5 26.6 26.8 14.2 17.9 4.7 11.3 21.5 23.7 7.2 79.6 13.7 17.2 3.1 25.1 61.7 11.5 20.3 21.4 4.6 15.9 29.0 19.7 27.9 13.7 0.0 49.8 18.5 3.6 3.3 10.6 4.0 6.6 5.9 13.2 20.3 22.2 TPD52 "D52, hD52, N8L" ENSG00000076554 "Tumor protein D52" P55327 8 80034745-80231232 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 187.6" "Cell type enhanced" "Detected in many" "Ionocytes: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 50.5" "Group enriched" "Detected in many" 5 "B-cells: 50.5;NK-cells: 15.1;T-cells: 22.0" "Cell line enhanced" "Detected in many" "Karpas-707: 252.6;SK-BR-3: 572.5" "HPA028427, HPA062167" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 310000 "Cluster 43: B-cells - Humoral immune response" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "Golgi apparatus" "HPA028427: AB_10610561, HPA062167: AB_2684704" "prognostic unfavorable (1.11e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-2)" "unprognostic (3.77e-3)" "unprognostic (8.24e-2)" "unprognostic (3.75e-1)" "unprognostic (7.99e-3)" "unprognostic (6.47e-2)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.77e-6)" "unprognostic (2.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (1.70e-2)" 5.4 9.2 34.9 28.4 40.2 8.9 75.9 34.2 69.4 19.6 36.6 117.7 98.9 9.9 56.2 34.9 15.3 31.1 11.7 42.9 35.4 46.5 30.7 19.8 44.0 33.2 37.1 2.4 41.8 27.4 34.3 22.9 36.3 104.8 129.7 187.6 80.7 18.3 8.6 46.9 100.3 10.4 32.8 16.0 84.1 5.2 53.3 15.5 64.5 9.8 56.2 20.9 20.2 48.1 131.8 34.9 1.6 23.0 0.0 0.0 51.7 8.6 12.9 34.7 17.1 18.0 37.4 189.9 45.2 0.8 25.5 52.5 52.7 36.3 24.6 23.8 44.2 26.8 46.9 29.4 0.2 8.6 0.7 0.0 25.2 0.1 12.2 21.6 2.0 128.9 0.4 252.6 0.1 43.6 42.6 39.4 11.7 148.8 86.0 0.3 0.7 122.0 60.7 31.6 64.9 44.1 40.1 572.5 110.7 51.0 55.9 34.2 2.1 0.0 35.2 0.6 30.8 94.1 87.1 155.2 22.5 0.2 2.6 0.6 0.1 5.5 12.7 0.1 22.0 50.5 12.4 11.1 2.5 44.7 8.1 9.3 0.5 15.1 0.1 5.2 9.1 8.3 34.9 40.2 34.2 69.4 42.9 35.4 33.2 37.1 36.3 32.8 53.3 48.1 17.3 44.8 67.8 10.4 133.6 80.7 89.6 83.4 51.2 171.1 105.6 54.2 22.2 82.9 78.1 66.2 118.9 98.9 28.6 230.9 170.2 112.8 20.6 25.2 8.4 26.2 169.9 11.6 85.4 79.6 116.9 6.7 97.3 72.8 1.3 15.3 25.7 40.6 13.1 32.0 53.9 331.9 476.0 14.6 24.2 13.0 1.2 10.8 104.9 37.5 91.2 50.3 60.8 69.9 181.0 79.7 317.5 1.5 270.5 214.4 132.3 135.3 21.4 232.2 0.0 49.6 8.3 1.6 18.2 91.4 124.6 231.2 51.3 0.3 247.1 135.4 TPO TPX ENSG00000115705 "Thyroid peroxidase" P07202 2 1374066-1543711 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 70 "thyroid gland: 1588.2" "Cell type enhanced" "Detected in some" "Adipocytes: 24.5;Early spermatids: 4.2;Endothelial cells: 12.6;Late spermatids: 7.5;Peritubular cells: 3.8" "Cancer enriched" "Detected in some" 364 "thyroid cancer: 188.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory CD4 T-cell: 2.0;T-reg: 1.2" "Lineage enriched" "Detected in single" 20 "T-cells: 2.0" "Group enriched" "Detected in some" 5 "Karpas-707: 9.9;RPMI-8226: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007987, CAB009587" Enhanced "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB009587: , HPA007987: AB_1080270" "unprognostic (1.55e-1)" "unprognostic (1.04e-1)" "unprognostic (2.88e-1)" "unprognostic (1.77e-2)" "unprognostic (3.56e-2)" "unprognostic (9.11e-2)" "unprognostic (2.24e-2)" "unprognostic (1.85e-1)" "unprognostic (1.32e-1)" "unprognostic (1.19e-4)" "unprognostic (2.61e-2)" "unprognostic (3.29e-1)" "unprognostic (5.44e-4)" "unprognostic (1.21e-1)" "unprognostic (3.73e-2)" "unprognostic (4.98e-3)" "unprognostic (7.10e-3)" 13.1 0.3 0.1 0.4 0.0 0.1 11.0 0.0 0.6 0.1 0.0 4.6 0.6 0.6 0.0 2.0 0.7 3.0 11.5 0.1 0.2 0.2 0.6 0.8 1.4 0.2 0.1 0.3 2.3 0.3 0.6 0.0 0.1 0.6 0.9 0.2 3.4 0.0 6.0 1.8 3.8 0.6 0.1 22.8 2.8 1.2 0.2 0.0 1588.2 5.6 0.4 2.1 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.9 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.2 0.1 0.0 0.0 0.6 0.1 0.2 0.2 0.1 0.1 0.1 0.2 0.4 24.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.2 0.0 0.2 12.6 0.0 0.0 2.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.5 0.6 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 1.1 3.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.8 0.3 0.5 0.1 0.0 0.0 0.2 0.1 0.0 0.1 TPP1 "CLN2, LPIC, SCAR7, TPP-1" ENSG00000166340 "Tripeptidyl peptidase 1" O14773 11 6612768-6619448 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 261.6;Kupffer cells: 376.5;Macrophages: 219.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037709, HPA044868" Enhanced "Intracellular and membrane" NA NA 9500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA037709: AB_10672913, HPA044868: AB_2679122" "unprognostic (8.27e-3)" "unprognostic (5.85e-2)" "unprognostic (7.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (2.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.54e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (4.46e-4)" "unprognostic (3.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-2)" 74.7 145.9 71.0 74.6 81.0 111.7 44.3 80.3 81.4 53.8 120.1 59.1 59.9 74.0 43.1 39.5 47.1 65.1 56.3 70.6 78.4 71.6 92.7 81.5 77.7 85.2 82.6 49.7 36.2 54.2 63.6 94.2 81.0 38.9 59.7 48.5 42.5 57.5 31.4 39.5 73.3 92.0 74.7 135.0 48.4 20.0 83.3 47.4 45.7 39.0 60.9 68.4 42.8 90.4 26.1 48.1 25.9 50.5 309.9 160.1 21.8 50.9 220.7 36.9 62.0 20.1 122.5 37.4 32.6 136.6 220.2 85.8 48.3 68.7 57.9 37.3 27.6 32.2 23.8 54.9 210.9 45.8 182.6 231.8 104.5 45.9 102.6 240.4 158.8 32.9 59.8 124.6 110.4 30.2 16.6 52.4 18.0 61.5 57.1 36.1 21.6 77.0 62.8 38.2 4.5 20.4 52.6 44.6 91.0 76.5 30.8 79.7 188.0 119.7 33.1 101.1 19.8 92.3 95.3 14.0 139.8 101.7 64.5 67.0 167.1 38.2 39.9 171.2 30.0 35.1 31.4 41.0 185.9 37.0 20.1 27.2 27.5 29.1 125.1 93.1 60.3 138.8 71.0 81.0 80.3 81.4 70.6 78.4 85.2 82.6 81.0 74.7 83.3 90.4 32.0 25.6 37.3 31.6 53.0 23.7 28.4 29.8 13.1 24.8 21.1 23.9 41.8 50.1 26.8 16.5 12.5 35.4 71.0 55.2 5.9 42.2 11.8 13.3 30.2 40.7 16.7 37.5 12.5 13.4 45.3 40.3 16.3 24.8 62.2 25.6 75.7 81.0 261.6 15.2 12.4 31.3 26.4 376.5 126.5 11.2 27.1 219.8 90.7 15.9 156.0 37.9 49.4 8.0 21.9 17.4 44.1 26.4 26.4 23.5 99.7 51.6 14.5 23.8 6.6 19.0 20.3 0.8 1.1 27.6 20.0 88.0 42.2 24.6 32.5 26.5 TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240379-1242554 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "granulocytes: 5873.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 893 "basophil: 89.3" "Lineage enriched" "Detected in single" 893 "granulocytes: 89.3" "Cell line enriched" "Detected in some" 166 "HMC-1: 3813.2" "CAB016369, CAB022175, HPA049153, HPA049554" Supported "Secreted to blood" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "CAB016369: AB_628406, CAB022175: , HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (2.06e-2)" "unprognostic (5.14e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-2)" "unprognostic (9.31e-3)" "prognostic favorable (9.62e-6)" "unprognostic (1.02e-1)" "unprognostic (4.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (4.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" 96.6 2.9 0.3 23.6 0.5 2.4 47.2 0.3 0.9 53.7 0.9 83.0 71.6 73.3 6.0 64.3 26.6 129.7 14.7 0.4 0.4 13.9 12.2 128.5 21.3 0.4 0.3 3.2 18.9 2.3 3.5 1.2 0.6 65.9 34.6 0.0 60.2 22.5 10.1 122.7 148.7 17.9 0.4 5.9 104.0 8.9 0.4 14.2 4.7 13.0 13.2 113.5 52.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 1.3 3813.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.3 2.1 6.1 0.5 0.4 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.1 1.1 0.0 0.0 2.8 22.9 2.0 89.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.5 0.3 0.9 0.4 0.4 0.4 0.3 0.6 0.4 0.4 0.3 0.0 25.6 135.5 0.0 2.9 18.6 5.1 0.0 1.2 0.0 0.9 0.1 0.3 0.0 8.1 0.0 0.0 0.0 0.2 0.9 0.0 1.2 0.3 0.0 0.0 4.1 0.0 3.8 0.0 0.0 0.2 7.6 0.5 0.0 5873.9 0.0 0.0 0.3 5.2 0.0 0.0 0.0 0.0 0.3 25.6 0.2 0.0 7.7 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 11.7 4.0 0.4 0.1 5.1 0.0 0.0 0.3 3.2 0.0 0.1 0.1 9.9 0.3 440.9 0.0 0.5 5.6 TPSB2 ENSG00000197253 "Tryptase beta 2" P20231 16 1227272-1230184 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 25 "granulocytes: 8966.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 50 "basophil: 5.0" "Lineage enriched" "Detected in single" 50 "granulocytes: 5.0" "Cell line enriched" "Detected in some" 7 "HMC-1: 297.5" "HPA049153, HPA049554" Supported "Secreted to blood" NA NA 16000000 "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (9.05e-2)" "unprognostic (8.46e-3)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (4.97e-3)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (8.55e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (8.30e-3)" "unprognostic (1.91e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-2)" "unprognostic (4.65e-2)" "unprognostic (3.17e-2)" 95.1 2.5 0.3 20.2 0.6 4.3 47.8 0.3 0.9 53.2 1.0 77.8 35.5 71.8 9.8 64.6 30.4 103.9 15.0 0.5 0.5 15.5 12.2 127.8 26.2 0.5 0.4 3.5 18.9 1.5 3.9 1.3 0.5 67.0 19.8 0.0 64.5 13.3 10.0 122.5 146.1 22.0 0.5 5.2 102.1 9.9 0.5 4.9 4.7 10.4 9.9 118.6 53.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.2 0.4 297.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 4.7 0.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.7 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.3 0.9 0.5 0.5 0.5 0.4 0.5 0.5 0.5 0.3 0.1 38.5 275.3 0.0 2.8 0.0 4.4 0.0 0.0 0.0 1.5 0.0 1.5 0.0 16.7 0.0 0.0 0.1 0.6 0.7 0.0 2.4 0.6 0.0 0.0 3.2 0.0 18.9 0.0 0.0 0.2 6.0 2.0 0.0 8966.1 0.0 0.0 0.0 3.8 0.0 0.1 0.7 0.0 0.0 0.0 1.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 25.8 5.4 0.7 0.1 3.6 0.0 0.0 0.4 1.1 0.0 0.7 0.0 0.0 0.1 345.1 0.0 1.0 6.1 TPSD1 ENSG00000095917 "Tryptase delta 1" Q9BZJ3 16 1256059-1259008 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 21.2" "Cell type enriched" "Detected in some" 19 "granulocytes: 202.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 29 "basophil: 2.9" "Lineage enriched" "Detected in single" 29 "granulocytes: 2.9" "Group enriched" "Detected in some" 49 "HEL: 28.2;HMC-1: 40.4" "CAB002215, CAB032871, HPA040182, HPA049554" Supported "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "CAB002215: AB_563870, CAB032871: AB_2206475, HPA040182: AB_2676875, HPA049554: AB_2680815" "unprognostic (5.99e-2)" "unprognostic (3.00e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "unprognostic (8.97e-3)" "unprognostic (1.15e-4)" "unprognostic (1.70e-1)" "unprognostic (5.45e-2)" "unprognostic (9.00e-2)" "unprognostic (2.88e-1)" "unprognostic (4.30e-1)" "unprognostic (2.94e-2)" "unprognostic (2.50e-3)" "unprognostic (3.74e-2)" "unprognostic (4.14e-1)" "unprognostic (3.89e-1)" "unprognostic (7.46e-3)" 8.0 0.5 1.2 1.9 1.3 1.6 4.5 1.3 2.7 5.1 1.0 7.8 3.8 8.5 1.9 8.1 3.2 13.8 1.1 1.4 1.1 1.2 0.7 17.8 5.4 1.4 1.3 0.3 1.5 0.1 0.4 0.1 1.5 5.5 0.8 0.1 4.8 1.2 1.4 9.5 13.4 5.4 1.1 0.4 21.2 1.3 1.4 1.2 0.3 1.0 2.3 13.3 5.0 1.2 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.2 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 1.3 2.7 1.4 1.1 1.4 1.3 1.5 1.1 1.4 1.2 0.0 3.2 7.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 10.5 0.0 0.0 0.0 0.2 0.0 0.0 202.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205317-66420543 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 76.5;Excitatory neurons: 101.9;Inhibitory neurons: 107.1;Spermatocytes: 97.1" "Cancer enhanced" "Detected in all" "glioma: 36.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 52.2;neutrophil: 35.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: AB_2732672" "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavorable (8.16e-6)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.73e-5)" 16.9 15.8 22.1 10.8 20.5 6.0 13.4 18.4 21.6 35.4 12.3 11.1 3.2 21.8 14.3 10.8 11.2 38.1 8.5 19.4 36.7 23.1 46.0 11.5 5.9 37.2 25.0 13.5 7.8 11.0 19.5 26.4 24.7 15.1 8.0 5.2 6.8 16.4 2.7 8.2 8.7 16.2 22.9 12.0 10.9 23.0 33.8 2.1 11.3 5.6 5.3 36.8 22.1 22.5 12.1 6.5 16.5 22.4 52.7 42.0 5.7 22.3 49.8 25.7 37.1 21.9 6.6 1.4 17.7 45.1 38.9 8.9 16.2 24.8 33.3 3.5 9.3 2.3 15.1 16.5 62.3 1.8 1.9 59.5 19.0 50.2 22.1 27.8 32.7 2.9 1.0 10.2 40.2 6.2 0.1 3.1 15.5 0.4 9.6 7.8 14.6 11.4 27.3 11.5 10.4 44.5 27.8 2.1 62.2 32.4 8.6 4.7 62.3 33.1 21.3 24.2 40.6 9.2 13.3 4.7 29.6 6.8 48.2 52.2 2.3 23.9 0.8 0.1 0.8 6.1 0.5 0.6 0.3 14.0 2.2 4.1 35.2 8.8 0.0 0.0 0.0 1.9 22.1 20.5 18.4 21.6 19.4 36.7 37.2 25.0 24.7 22.9 33.8 22.5 33.8 0.0 8.9 38.8 11.5 10.8 7.7 24.4 33.6 8.5 4.0 13.3 1.6 5.7 9.6 31.3 2.1 1.8 3.8 0.2 9.8 23.0 11.2 13.3 76.5 17.9 7.7 1.3 101.9 47.6 4.3 58.5 12.2 9.7 4.5 12.2 10.0 34.1 16.2 6.7 107.1 0.8 8.2 8.9 8.9 11.6 48.1 6.2 14.2 32.8 15.8 5.0 1.0 61.3 38.8 23.7 0.1 37.2 7.1 5.3 0.0 3.2 19.5 3.6 6.6 16.4 21.6 97.1 41.3 15.1 7.5 3.8 2.8 12.6 0.7 7.7 TPST2 TANGO13B ENSG00000128294 "Tyrosylprotein sulfotransferase 2" O60704 22 26521996-26596717 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 398.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.0;NK-cells: 263.7;Plasma cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021054 Enhanced "Intracellular and membrane" NA NA 88000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA021054: AB_1858221" "unprognostic (2.24e-1)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "prognostic favorable (8.08e-5)" "unprognostic (8.88e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-2)" "unprognostic (3.38e-1)" "unprognostic (2.70e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (2.34e-6)" "unprognostic (9.68e-2)" "unprognostic (9.21e-3)" "unprognostic (5.62e-2)" "unprognostic (2.01e-1)" 24.4 31.0 24.4 15.2 20.8 23.1 21.8 19.1 29.9 17.4 26.9 11.5 13.6 18.0 111.6 18.7 17.0 12.2 27.5 23.4 22.9 24.9 74.9 45.7 19.1 22.0 24.2 9.2 398.8 5.3 9.9 41.8 20.8 16.0 8.8 3.3 10.9 17.8 38.5 18.4 13.4 12.1 23.1 36.4 11.7 20.6 34.2 10.7 38.8 22.6 17.0 17.1 17.3 20.7 12.8 9.1 11.7 6.0 24.4 18.7 16.4 27.9 49.9 22.2 20.3 6.2 6.5 21.4 7.3 50.4 11.6 19.5 8.8 19.2 12.7 8.8 16.9 51.8 5.6 13.1 10.2 6.0 158.7 20.1 30.3 22.5 7.7 22.5 41.6 9.6 52.6 65.2 17.2 14.3 24.3 40.7 15.4 10.0 9.1 22.5 15.8 60.2 6.7 14.3 8.8 6.1 12.9 11.2 16.0 17.0 5.2 24.7 33.2 27.3 61.2 22.5 27.3 20.9 31.5 20.6 20.7 23.1 25.3 490.4 77.0 111.9 249.2 86.3 70.5 23.6 57.0 187.2 48.3 25.6 27.8 163.6 163.0 354.9 94.3 115.3 71.9 240.7 24.4 20.8 19.1 29.9 23.4 22.9 22.0 24.2 20.8 23.1 34.2 20.7 37.3 16.0 12.6 13.7 30.8 38.1 82.5 29.9 14.2 9.0 10.8 13.1 15.5 47.1 14.4 22.0 6.2 171.0 120.8 6.7 27.4 12.9 15.2 31.1 14.8 66.1 0.0 64.6 23.4 65.1 49.8 10.7 5.1 39.5 53.7 13.9 113.6 79.3 123.9 6.7 20.3 9.3 12.2 55.9 48.6 4.5 5.3 70.1 28.4 47.8 32.4 1.9 263.7 5.0 1.9 53.1 8.7 4.1 183.7 36.4 16.5 7.6 18.6 5.3 6.6 9.9 15.3 2.9 13.2 15.1 35.9 143.0 64.4 42.0 11.8 83.7 TRABD2A "C2orf89, TIKI1" ENSG00000186854 "TraB domain containing 2A" Q86V40 2 84821650-84907008 "Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 42.7;lymphoid tissue: 11.4;ovary: 26.7" "Cell type enhanced" "Detected in many" "Early spermatids: 575.5;Granulosa cells: 108.7;Late spermatids: 326.8;Undifferentiated cells: 141.9" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 14.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 71.9" "Lineage enriched" "Detected in many" 18 "T-cells: 71.9" "Cell line enhanced" "Detected in many" "BEWO: 41.7;HDLM-2: 35.1;HSkMC: 22.3;hTEC/SVTERT24-B: 17.8;SiHa: 17.8" HPA045817 Approved "Intracellular and membrane" NA NA 18000 "Cluster 32: T-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "HPA045817: AB_2679460" "unprognostic (7.49e-3)" "unprognostic (3.35e-1)" "unprognostic (3.08e-1)" "unprognostic (3.29e-2)" "unprognostic (3.82e-5)" "unprognostic (2.46e-2)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "unprognostic (6.68e-2)" "unprognostic (1.66e-1)" "unprognostic (1.16e-1)" "unprognostic (4.96e-2)" "unprognostic (1.47e-4)" "unprognostic (4.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.41e-3)" "unprognostic (1.37e-1)" 2.5 0.4 2.1 8.9 2.1 3.7 2.2 0.3 3.4 0.3 0.3 40.0 4.2 0.2 0.7 0.3 0.8 0.5 0.3 1.9 1.5 0.6 1.0 2.8 11.4 0.3 2.7 26.7 0.1 2.1 0.3 0.9 0.3 0.2 42.7 0.0 0.5 0.1 0.1 1.0 10.7 2.8 0.4 3.8 1.1 0.4 3.8 8.1 0.4 0.6 7.8 0.7 0.4 1.6 1.3 1.1 0.4 0.2 12.4 13.4 41.7 2.0 3.3 5.8 10.8 0.5 4.7 0.0 0.5 6.5 10.8 0.0 2.8 0.6 8.6 35.1 0.7 0.0 8.4 0.0 1.5 0.1 0.0 22.3 0.0 17.8 8.1 1.3 0.0 0.3 0.0 0.1 0.8 0.0 0.1 0.1 1.1 2.3 0.9 0.3 0.7 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.2 0.3 0.0 0.2 0.3 5.8 0.8 0.0 2.1 4.0 0.0 0.1 5.3 3.5 0.0 0.0 0.3 0.0 8.5 0.3 10.5 0.7 33.6 12.4 1.8 3.9 71.9 46.1 1.3 3.9 0.2 1.6 23.5 13.2 2.1 2.1 0.3 3.4 1.9 1.5 0.3 2.7 0.3 0.4 3.8 1.6 9.0 3.2 11.0 0.0 7.8 1.0 0.6 0.6 0.0 1.1 1.4 0.4 85.4 0.0 0.9 0.0 0.0 9.4 4.6 51.1 0.0 0.1 575.5 4.3 0.6 7.5 12.7 0.8 10.6 0.9 41.5 6.1 2.6 1.9 2.5 108.7 2.2 0.1 2.6 0.0 0.7 67.9 0.0 1.3 6.6 326.8 5.0 4.6 3.6 3.7 12.6 0.0 3.1 1.0 0.7 0.6 73.8 2.6 5.4 0.5 17.4 1.2 1.7 0.1 6.6 0.9 7.3 3.5 5.6 0.4 0.6 4.4 29.7 0.2 141.9 0.5 TRABD2B TIKI2 ENSG00000269113 "TraB domain containing 2B" A6NFA1 1 47760528-47997385 "Predicted intracellular proteins" "Wnt signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.5;Cholangiocytes: 15.7;Fibroblasts: 6.6;Hepatocytes: 11.3;Microglial cells: 7.5;Proximal tubular cells: 22.8" "Cancer enriched" "Detected in many" 7 "renal cancer: 12.8" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HeLa: 6.7;U-2197: 13.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA045817 Approved "Intracellular and membrane" NA NA 41000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA045817: AB_2679460" "unprognostic (2.38e-2)" "unprognostic (6.77e-2)" "unprognostic (1.19e-2)" "unprognostic (2.26e-2)" "unprognostic (5.65e-2)" "unprognostic (4.49e-2)" "unprognostic (3.16e-2)" "unprognostic (1.24e-1)" "unprognostic (2.74e-1)" "unprognostic (3.29e-3)" "unprognostic (1.84e-1)" "unprognostic (2.95e-1)" "unprognostic (1.41e-2)" "unprognostic (2.41e-2)" "unprognostic (4.77e-1)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" 2.3 0.9 0.1 0.6 0.2 0.0 2.7 1.0 0.3 2.8 0.5 2.9 0.4 1.5 0.8 1.3 1.9 1.6 7.0 0.1 0.0 16.6 4.2 1.7 0.0 0.1 0.2 0.8 2.6 0.0 1.5 0.4 0.2 3.6 0.7 0.0 1.6 3.3 0.6 1.6 1.6 0.9 0.1 1.2 1.6 0.9 0.1 0.4 1.0 0.6 0.1 3.8 2.6 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.2 0.0 6.7 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.4 13.2 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.0 0.3 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.2 1.6 0.0 0.5 0.3 0.3 0.8 1.4 0.6 2.8 0.0 0.6 2.9 7.5 15.7 0.1 1.8 0.0 0.0 0.0 0.0 5.9 3.8 0.1 0.1 0.5 1.9 0.0 0.0 0.3 2.2 0.0 6.6 0.0 0.1 0.0 0.0 1.4 11.3 0.1 0.0 0.3 0.1 0.0 0.0 0.9 0.3 0.0 0.3 0.0 7.5 0.0 0.0 0.0 0.5 0.7 1.3 0.0 2.2 0.1 0.4 0.0 22.8 0.0 0.0 0.0 0.3 4.1 0.0 4.0 0.1 0.3 0.0 0.2 0.1 0.0 0.2 TRAV1-1 "TCRAV1S1, TCRAV7S1, TRAV11" ENSG00000255569 "T cell receptor alpha variable 1-1" A0A0B4J248 14 21621838-21622567 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 17.9" "Cell type enriched" "Detected in single" 10 "T-cells: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 18 "MAIT T-cell: 26.0;memory CD4 T-cell: 11.8;memory CD8 T-cell: 27.1;naive CD4 T-cell: 17.7;naive CD8 T-cell: 25.7;T-reg: 30.6" "Lineage enriched" "Detected in many" 23 "T-cells: 30.6" "Cell line enriched" "Detected in single" 160 "MOLT-4: 30.7" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.56e-1)" "unprognostic (6.87e-2)" "unprognostic (5.07e-1)" "unprognostic (6.72e-4)" "unprognostic (2.62e-3)" "unprognostic (6.08e-3)" "unprognostic (2.29e-1)" "unprognostic (6.56e-2)" "unprognostic (4.69e-2)" "unprognostic (2.96e-1)" "unprognostic (9.40e-5)" "unprognostic (3.51e-2)" "unprognostic (3.14e-1)" "unprognostic (1.40e-1)" 0.2 0.0 0.0 2.7 0.0 0.7 0.1 0.0 0.1 0.6 0.0 0.6 0.6 0.2 0.0 0.2 0.1 1.1 0.0 0.0 0.0 0.1 0.1 0.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.1 1.1 0.0 0.0 1.9 1.3 0.1 0.0 17.9 0.1 0.0 3.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 26.0 0.0 11.8 27.1 0.2 0.0 17.7 25.7 0.0 0.0 0.0 0.0 30.6 6.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 TRAV1-2 ENSG00000256553 "T cell receptor alpha variable 1-2" A0A0B4J238 14 21642889-21643578 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 19.3" "Cell type enriched" "Detected in single" 6 "T-cells: 4.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "MAIT T-cell: 2027.8" "Lineage enriched" "Detected in many" 507 "T-cells: 2027.8" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.19e-3)" "unprognostic (1.29e-3)" "unprognostic (1.59e-2)" "unprognostic (1.84e-3)" "unprognostic (5.87e-3)" "unprognostic (1.55e-3)" "unprognostic (3.56e-2)" "unprognostic (8.90e-2)" "unprognostic (6.50e-4)" "unprognostic (3.16e-1)" "unprognostic (1.68e-1)" "unprognostic (1.13e-2)" "unprognostic (2.15e-1)" "unprognostic (1.43e-1)" "unprognostic (8.99e-2)" "unprognostic (8.30e-2)" 0.3 0.7 0.0 4.5 0.0 1.3 0.4 0.0 0.4 0.6 0.0 1.2 1.6 0.3 0.3 0.5 0.7 3.1 0.1 0.0 0.0 0.2 1.1 2.0 7.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 1.1 0.0 0.3 0.0 0.0 0.4 1.3 0.3 0.1 4.6 1.5 0.1 0.0 19.3 0.5 0.0 7.2 2.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 0.7 1.0 0.6 2027.8 0.4 44.9 311.2 0.8 0.2 40.9 70.0 3.9 0.3 1.3 1.7 79.5 40.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 TRAV10 "TCRAV10S1, TCRAV24S1" ENSG00000211784 "T cell receptor alpha variable 10" A0A0B4J240 14 21825472-21826075 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 16 "lymphoid tissue: 16.2" "Cell type enriched" "Detected in single" 6 "T-cells: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 64 "MAIT T-cell: 24.7;memory CD4 T-cell: 38.3;memory CD8 T-cell: 43.3;naive CD4 T-cell: 42.5;naive CD8 T-cell: 25.0;T-reg: 59.4" "Lineage enriched" "Detected in single" 156 "T-cells: 59.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.58e-3)" "unprognostic (1.27e-3)" "unprognostic (1.74e-2)" "unprognostic (5.74e-4)" "unprognostic (3.80e-4)" "unprognostic (2.97e-3)" "unprognostic (1.91e-1)" "unprognostic (5.63e-2)" "unprognostic (7.70e-2)" "unprognostic (2.78e-1)" "unprognostic (4.67e-5)" "unprognostic (2.49e-1)" "unprognostic (1.91e-2)" "unprognostic (1.66e-1)" 0.2 0.2 0.0 3.5 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.6 0.1 0.2 0.0 0.3 0.1 0.9 0.0 0.0 0.0 0.1 0.2 0.9 5.8 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 0.7 0.0 0.0 16.2 0.1 0.0 5.3 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 24.7 0.1 38.3 43.3 0.0 0.1 42.5 25.0 0.3 0.0 0.2 0.3 59.4 14.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 TRAV12-1 ENSG00000211785 "T cell receptor alpha variable 12-1" A0A0B4J245 14 21841240-21841774 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 21.1" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 4.1;Plasma cells: 1.4;T-cells: 6.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 72 "MAIT T-cell: 128.5;memory CD4 T-cell: 205.2;memory CD8 T-cell: 199.7;naive CD4 T-cell: 138.6;naive CD8 T-cell: 251.7;T-reg: 193.9" "Lineage enriched" "Detected in many" 97 "T-cells: 251.7" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (4.83e-3)" "unprognostic (9.56e-5)" "unprognostic (2.18e-2)" "unprognostic (3.33e-3)" "unprognostic (8.05e-2)" "unprognostic (2.99e-4)" "unprognostic (3.16e-4)" "unprognostic (3.23e-2)" "unprognostic (1.77e-3)" "unprognostic (1.15e-1)" "unprognostic (6.92e-2)" "unprognostic (3.97e-4)" "unprognostic (1.39e-1)" "unprognostic (7.99e-2)" "unprognostic (2.14e-1)" "unprognostic (2.92e-2)" 0.5 0.0 0.0 6.5 0.0 1.2 1.3 0.0 0.2 0.6 0.0 1.3 2.8 0.4 0.8 0.7 0.4 2.5 0.1 0.0 0.0 0.1 0.5 1.3 13.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.0 0.2 0.0 0.4 0.0 2.3 1.2 0.0 4.9 1.9 0.1 0.0 21.1 0.2 0.2 14.3 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.8 0.9 1.9 0.4 128.5 0.2 205.2 199.7 0.3 0.6 138.6 251.7 2.6 0.3 1.0 0.2 193.9 100.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 TRAV12-2 ENSG00000211789 "T cell receptor alpha variable 12-2" A0A075B6T6 14 21887857-21888502 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 22.4" "Cell type enriched" "Detected in some" 6 "T-cells: 6.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 17 "memory CD4 T-cell: 101.9;memory CD8 T-cell: 87.7;naive CD4 T-cell: 90.3;naive CD8 T-cell: 65.2;T-reg: 143.3" "Lineage enriched" "Detected in many" 77 "T-cells: 143.3" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.74e-2)" "unprognostic (4.98e-3)" "unprognostic (4.75e-2)" "unprognostic (2.41e-4)" "unprognostic (2.22e-2)" "unprognostic (7.44e-2)" "unprognostic (5.23e-4)" "unprognostic (1.73e-3)" "unprognostic (1.74e-1)" "unprognostic (1.43e-1)" "unprognostic (1.03e-3)" "unprognostic (3.69e-1)" "unprognostic (3.34e-3)" "unprognostic (9.87e-2)" "unprognostic (3.01e-2)" 0.8 0.8 0.0 7.5 0.0 0.9 1.0 0.0 0.1 1.0 0.0 1.6 4.1 0.8 0.5 0.8 1.2 2.5 0.3 0.0 0.0 0.3 0.6 2.5 15.7 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.2 0.8 2.1 0.0 1.7 0.1 0.2 0.5 2.9 0.5 0.0 5.9 2.3 0.0 0.0 22.4 0.6 0.0 13.5 3.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.5 1.2 0.0 5.7 0.1 101.9 87.7 0.2 0.1 90.3 65.2 1.8 0.1 0.2 0.1 143.3 27.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 TRAV12-3 "TCRAV12S3, TCRAV2S2, TRAV123" ENSG00000211794 "T cell receptor alpha variable 12-3" A0A0B4J271 14 21965451-21966061 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 60.3" "Group enriched" "Detected in some" 4 "Erythroid cells: 1.7;T-cells: 6.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 186.5;T-reg: 256.6" "Lineage enriched" "Detected in many" 23 "T-cells: 256.6" "Cell line enriched" "Detected in single" 43 "JURKAT: 4.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.62e-4)" "unprognostic (7.68e-4)" "unprognostic (5.17e-2)" "unprognostic (1.33e-3)" "unprognostic (2.32e-1)" "unprognostic (1.80e-3)" "unprognostic (2.50e-2)" "unprognostic (1.17e-1)" "unprognostic (7.55e-4)" "unprognostic (9.00e-3)" "unprognostic (1.03e-1)" "unprognostic (1.20e-1)" "unprognostic (4.52e-5)" "unprognostic (3.75e-1)" "unprognostic (4.98e-2)" "unprognostic (5.80e-2)" "unprognostic (1.68e-2)" 0.5 0.1 0.0 9.3 0.0 1.5 1.1 0.0 0.1 1.7 0.0 2.1 2.2 0.6 0.9 0.4 0.6 6.1 0.5 0.0 0.0 0.3 0.4 2.8 18.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 3.2 0.0 0.3 0.2 0.1 0.4 2.7 0.5 0.0 4.6 1.9 0.1 0.0 60.3 0.2 0.0 17.4 3.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.5 0.2 0.4 0.2 12.7 0.4 186.5 57.4 0.4 1.8 119.7 153.3 4.6 0.9 0.7 0.5 256.6 48.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 TRAV13-1 ENSG00000211788 "T cell receptor alpha variable 13-1" A0A0B4J241 14 21868839-21869365 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 62.5" "Cell type enriched" "Detected in single" 26 "T-cells: 15.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 329.3" "Lineage enriched" "Detected in many" 28 "T-cells: 329.3" "Cell line enriched" "Detected in single" 20 "JURKAT: 1.9" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.10e-3)" "unprognostic (9.80e-3)" "unprognostic (1.60e-2)" "unprognostic (3.04e-3)" "unprognostic (5.71e-2)" "unprognostic (3.30e-5)" "unprognostic (7.68e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-2)" "unprognostic (1.15e-1)" "unprognostic (7.16e-5)" "unprognostic (1.03e-1)" "unprognostic (4.95e-2)" "unprognostic (1.20e-2)" "unprognostic (5.59e-2)" 1.1 0.3 0.0 13.7 0.1 2.2 1.1 0.0 0.2 0.2 0.0 3.7 3.6 0.7 0.3 0.8 0.9 3.7 0.5 0.0 0.0 0.4 1.0 4.4 29.2 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.0 1.1 3.0 0.0 1.2 0.4 0.2 0.2 7.5 0.4 0.0 8.4 3.8 0.2 0.0 62.5 0.6 0.7 29.9 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.7 0.4 1.4 0.4 62.6 0.4 203.8 179.6 0.5 0.6 232.3 292.5 6.2 0.5 0.5 0.9 329.3 80.2 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.6 0.0 0.0 0.0 TRAV13-2 ENSG00000211791 "T cell receptor alpha variable 13-2" A0A0B4J235 14 21918188-21918756 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "lymphoid tissue: 51.7" "Group enriched" "Detected in some" 4 "NK-cells: 4.1;T-cells: 5.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 38 "MAIT T-cell: 32.9;memory CD4 T-cell: 94.0;memory CD8 T-cell: 57.3;naive CD4 T-cell: 101.8;naive CD8 T-cell: 114.1;T-reg: 114.8" "Lineage enriched" "Detected in many" 53 "T-cells: 114.8" "Cell line enriched" "Detected in some" 4 "JURKAT: 6.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.15e-3)" "unprognostic (1.47e-2)" "unprognostic (2.07e-2)" "unprognostic (1.26e-3)" "unprognostic (5.58e-1)" "unprognostic (4.38e-4)" "unprognostic (1.08e-1)" "unprognostic (6.47e-2)" "unprognostic (2.85e-2)" "unprognostic (4.16e-2)" "unprognostic (2.12e-1)" "unprognostic (2.99e-1)" "unprognostic (3.66e-4)" "unprognostic (1.52e-1)" "unprognostic (9.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.77e-2)" 0.3 0.0 0.0 6.6 0.0 1.4 0.9 0.0 0.2 0.4 0.0 1.3 2.1 0.2 1.2 0.7 0.3 1.4 0.2 0.0 0.0 0.2 0.4 1.6 14.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 1.0 0.0 0.5 0.1 0.1 0.5 1.6 0.5 0.1 4.6 1.9 0.2 0.0 51.7 0.2 0.0 10.0 1.9 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 6.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.1 2.2 0.2 32.9 0.4 94.0 57.3 0.1 0.2 101.8 114.1 2.1 0.6 0.2 0.3 114.8 40.6 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 5.7 0.0 0.0 0.0 TRAV14DV4 "hADV14S1, TCRAV6S1-hDV104S1, TRAV14/DV4" ENSG00000211792 "T cell receptor alpha variable 14/delta variable 4" A0A0A6YYC5 14 21924063-21924651 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 25.7" "Cell type enriched" "Detected in single" 12 "T-cells: 6.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 38.2;memory CD8 T-cell: 78.1;naive CD4 T-cell: 30.7;naive CD8 T-cell: 122.3;T-reg: 42.6" "Lineage enriched" "Detected in single" 176 "T-cells: 122.3" "Cell line enhanced" "Detected in single" "JURKAT: 1.6" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.82e-3)" "unprognostic (1.00e-2)" "unprognostic (1.43e-1)" "unprognostic (3.06e-3)" "unprognostic (3.00e-5)" "unprognostic (2.52e-1)" "unprognostic (7.61e-4)" "unprognostic (3.77e-1)" "unprognostic (2.82e-2)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (2.62e-5)" "unprognostic (3.01e-1)" "unprognostic (4.17e-2)" "unprognostic (2.90e-1)" "unprognostic (1.60e-2)" 0.6 0.1 0.0 4.2 0.0 1.5 0.6 0.0 0.1 0.5 0.0 0.8 2.0 0.3 0.0 0.6 0.6 1.6 0.2 0.0 0.0 0.2 1.1 2.5 12.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.2 0.1 0.0 0.2 1.7 0.1 0.0 3.4 1.3 0.0 0.0 25.7 0.2 0.0 8.0 1.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.2 9.9 0.1 38.2 78.1 0.0 0.2 30.7 122.3 0.3 0.4 0.3 0.0 42.6 21.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 TRAV16 "TCRAV16S1, TCRAV9S1" ENSG00000211796 "T cell receptor alpha variable 16" A0A0A6YYK6 14 21990496-21990938 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 39.8" "Cell type enhanced" "Detected in some" "Erythroid cells: 1.3;Gastric mucus-secreting cells: 3.1;T-cells: 5.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 48.0;T-reg: 58.0" "Lineage enriched" "Detected in single" 164 "T-cells: 58.0" "Cell line enriched" "Detected in single" 184 "JURKAT: 18.3" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.93e-2)" "unprognostic (1.06e-4)" "unprognostic (6.22e-3)" "unprognostic (3.67e-3)" "unprognostic (1.01e-4)" "unprognostic (1.01e-1)" "unprognostic (4.08e-2)" "unprognostic (2.79e-2)" "unprognostic (6.94e-4)" "unprognostic (5.25e-2)" "unprognostic (2.33e-1)" "unprognostic (5.27e-5)" "unprognostic (1.55e-1)" "unprognostic (3.91e-2)" "unprognostic (4.01e-1)" "unprognostic (2.07e-3)" 0.2 0.0 0.0 5.7 0.0 0.8 0.8 0.0 0.3 0.5 0.0 1.5 1.9 0.2 1.3 0.5 0.2 2.6 0.1 0.0 0.0 0.6 0.2 1.8 16.6 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.4 1.7 0.0 0.6 0.1 0.0 0.6 1.6 0.0 0.0 2.8 1.7 0.1 0.1 39.8 0.3 0.0 10.1 3.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 11.9 0.0 45.6 18.2 0.0 0.1 48.0 22.4 0.3 0.0 0.0 0.0 58.0 10.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 TRAV17 "TCRAV17S1, TCRAV3S1" ENSG00000211797 "T cell receptor alpha variable 17" A0A0B4J275 14 21997539-21998168 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 27.8" "Cell type enriched" "Detected in some" 5 "T-cells: 6.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "memory CD4 T-cell: 81.4;memory CD8 T-cell: 63.7;naive CD4 T-cell: 61.8;naive CD8 T-cell: 53.2;T-reg: 116.3" "Lineage enriched" "Detected in single" 226 "T-cells: 116.3" "Cell line enriched" "Detected in single" 221 "JURKAT: 22.0" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (8.22e-4)" "unprognostic (4.50e-3)" "unprognostic (1.37e-3)" "unprognostic (2.06e-2)" "unprognostic (2.72e-6)" "unprognostic (6.44e-2)" "unprognostic (7.45e-2)" "unprognostic (1.28e-2)" "unprognostic (1.67e-3)" "unprognostic (8.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.58e-5)" "unprognostic (1.73e-1)" "unprognostic (8.43e-3)" "unprognostic (8.53e-2)" "unprognostic (2.21e-1)" 0.2 0.0 0.0 5.9 0.0 0.5 0.2 0.0 0.2 0.5 0.0 1.2 1.8 0.3 0.8 0.6 0.6 1.4 0.1 0.0 0.0 0.2 0.4 1.4 13.2 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.6 1.6 0.0 0.1 0.0 0.0 0.1 1.5 0.3 0.0 3.3 2.2 0.1 0.0 27.8 0.3 0.0 10.2 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.7 0.0 3.9 0.2 81.4 63.7 0.0 0.2 61.8 53.2 0.5 0.1 0.1 0.3 116.3 22.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 TRAV18 TCRAV18S1 ENSG00000211798 "T cell receptor alpha variable 18" A0A075B6X5 14 22003106-22003673 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "lymphoid tissue: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 5.6;memory CD8 T-cell: 6.3;naive CD4 T-cell: 12.4;naive CD8 T-cell: 7.9;T-reg: 5.1" "Lineage enriched" "Detected in single" 124 "T-cells: 12.4" "Cell line enriched" "Detected in some" 7 "JURKAT: 36.2" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.30e-2)" "unprognostic (6.59e-3)" "unprognostic (2.94e-2)" "unprognostic (1.31e-1)" "unprognostic (1.92e-1)" "unprognostic (2.67e-1)" "unprognostic (9.94e-2)" "unprognostic (1.02e-2)" "unprognostic (7.00e-2)" "unprognostic (1.92e-1)" "unprognostic (5.61e-4)" 0.0 0.0 0.0 0.7 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 1.0 0.8 0.4 0.0 9.8 0.2 0.5 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 5.6 6.3 0.0 0.0 12.4 7.9 0.0 0.0 0.0 0.0 5.1 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 TRAV19 "TCRAV12S1, TCRAV19S1" ENSG00000211799 "T cell receptor alpha variable 19" A0A0A6YYK7 14 22007512-22008181 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 36.8" "Cell type enhanced" "Detected in single" "T-cells: 2.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "memory CD4 T-cell: 17.8;memory CD8 T-cell: 45.6;naive CD4 T-cell: 23.2;naive CD8 T-cell: 24.5;T-reg: 23.9" "Lineage enriched" "Detected in single" 173 "T-cells: 45.6" "Cell line enriched" "Detected in some" 19 "JURKAT: 26.2" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (5.04e-3)" "unprognostic (2.11e-2)" "unprognostic (2.19e-2)" "unprognostic (1.04e-3)" "unprognostic (1.52e-1)" "unprognostic (2.95e-4)" "unprognostic (2.15e-3)" "unprognostic (1.50e-1)" "unprognostic (4.92e-2)" "unprognostic (2.99e-3)" "unprognostic (1.15e-1)" "unprognostic (3.41e-1)" "unprognostic (3.79e-2)" "unprognostic (1.22e-1)" "unprognostic (7.40e-2)" "unprognostic (1.18e-1)" "unprognostic (4.33e-3)" 0.4 0.4 0.0 6.1 0.0 1.2 0.9 0.0 0.0 0.7 0.0 1.3 2.7 0.5 0.4 1.0 0.3 2.4 0.7 0.0 0.1 0.5 0.6 3.2 18.2 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.5 3.1 0.0 1.2 0.4 0.0 0.3 2.3 0.6 0.1 6.5 3.7 0.8 0.0 36.8 0.4 0.3 12.7 3.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 2.6 0.0 17.8 45.6 0.0 0.0 23.2 24.5 0.2 0.0 0.0 0.0 23.9 8.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 TRAV2 ENSG00000211776 "T cell receptor alpha variable 2" A0A0B4J234 14 21712321-21712843 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 21 "lymphoid tissue: 56.3" "Cell type enriched" "Detected in single" 5 "T-cells: 2.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 40.9" "Lineage enriched" "Detected in single" 124 "T-cells: 40.9" "Cell line enriched" "Detected in single" 21 "Daudi: 2.1" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.38e-2)" "unprognostic (6.44e-3)" "unprognostic (7.50e-2)" "unprognostic (1.93e-2)" "unprognostic (1.86e-3)" "unprognostic (3.64e-2)" "unprognostic (4.45e-2)" "unprognostic (2.00e-2)" "unprognostic (1.06e-2)" "unprognostic (1.24e-1)" "unprognostic (5.84e-2)" "unprognostic (9.93e-5)" "unprognostic (1.92e-1)" "unprognostic (4.86e-2)" "unprognostic (1.15e-1)" "unprognostic (3.45e-2)" 0.4 0.2 0.0 8.2 0.0 2.5 0.3 0.0 0.5 0.3 0.0 2.0 0.8 0.0 0.0 0.9 0.3 0.9 0.3 0.0 0.0 0.2 0.3 1.6 19.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.8 0.0 0.2 0.0 0.0 0.1 1.7 0.0 0.0 3.3 2.7 0.2 0.0 56.3 0.2 0.0 13.2 2.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 31.3 0.0 31.5 9.9 0.0 0.0 24.5 9.6 0.1 0.0 0.0 0.3 40.9 5.7 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 TRAV20 ENSG00000211800 "T cell receptor alpha variable 20" A0A0B4J274 14 22040594-22041153 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 14.6" "Cell type enriched" "Detected in single" 6 "T-cells: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 124.2;memory CD8 T-cell: 94.6;naive CD4 T-cell: 124.6;naive CD8 T-cell: 98.0;T-reg: 152.3" "Lineage enriched" "Detected in many" 60 "T-cells: 152.3" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.70e-2)" "unprognostic (3.31e-3)" "unprognostic (6.84e-2)" "unprognostic (2.90e-3)" "unprognostic (1.14e-2)" "unprognostic (1.93e-3)" "unprognostic (2.21e-2)" "unprognostic (4.70e-2)" "unprognostic (8.88e-2)" "unprognostic (7.00e-2)" "unprognostic (3.95e-2)" "unprognostic (1.16e-4)" "unprognostic (1.80e-1)" "unprognostic (3.26e-2)" "unprognostic (1.64e-1)" "unprognostic (2.11e-2)" 0.1 0.1 0.0 3.3 0.0 0.2 0.3 0.0 0.1 0.5 0.0 0.7 0.4 0.2 0.0 0.2 0.1 1.7 0.1 0.0 0.0 0.1 0.6 1.4 9.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.7 0.0 0.6 0.2 0.1 0.0 0.8 0.5 0.0 2.4 0.8 0.0 0.0 14.6 0.3 0.0 7.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.5 0.1 15.6 1.6 124.2 94.6 0.0 0.1 124.6 98.0 2.5 0.2 0.4 0.4 152.3 40.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 TRAV21 ENSG00000211801 "T cell receptor alpha variable 21" A0A0B4J279 14 22052514-22053056 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "lymphoid tissue: 63.2" "Group enriched" "Detected in some" 12 "Gastric mucus-secreting cells: 6.1;T-cells: 23.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 220.5;memory CD8 T-cell: 233.5;naive CD4 T-cell: 198.6;naive CD8 T-cell: 204.8;T-reg: 391.9" "Lineage enriched" "Detected in many" 76 "T-cells: 391.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.53e-4)" "unprognostic (1.03e-2)" "unprognostic (3.94e-3)" "unprognostic (3.69e-4)" "unprognostic (1.74e-1)" "unprognostic (1.22e-3)" "unprognostic (4.86e-3)" "unprognostic (2.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.87e-3)" "unprognostic (4.20e-2)" "unprognostic (9.80e-2)" "unprognostic (4.53e-3)" "unprognostic (3.13e-1)" "unprognostic (2.96e-2)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" 0.4 0.1 0.0 5.9 0.0 0.8 1.4 0.0 0.1 1.1 0.0 1.8 2.0 0.1 1.7 0.9 0.7 1.7 0.1 0.0 0.1 0.7 0.5 2.7 14.2 0.2 0.0 0.4 0.0 0.1 0.0 0.3 0.1 0.7 2.7 0.0 1.0 0.1 0.4 0.3 2.6 0.7 0.1 5.4 2.4 0.1 0.0 63.2 3.8 0.0 17.0 2.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.9 1.7 0.2 17.4 0.5 220.5 233.5 0.9 0.8 198.6 204.8 5.1 0.4 0.7 0.6 391.9 73.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.0 0.0 0.0 0.0 TRAV22 "TCRAV13S1, TCRAV22S1" ENSG00000211802 "T cell receptor alpha variable 22" A0A0B4J277 14 22070557-22071208 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "lymphoid tissue: 22.8" "Group enriched" "Detected in some" 4 "NK-cells: 1.0;T-cells: 3.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 59.6" "Lineage enriched" "Detected in many" 6 "T-cells: 59.6" "Cell line enriched" "Detected in single" 5 "U-266/70: 2.7" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.18e-2)" "unprognostic (6.03e-2)" "unprognostic (3.52e-2)" "unprognostic (1.82e-3)" "unprognostic (3.00e-5)" "unprognostic (4.27e-1)" "unprognostic (3.45e-2)" "unprognostic (2.51e-2)" "unprognostic (1.40e-2)" "unprognostic (4.79e-2)" "unprognostic (2.93e-2)" "unprognostic (2.63e-5)" "unprognostic (6.15e-2)" "unprognostic (1.12e-2)" "unprognostic (7.56e-3)" "unprognostic (3.15e-2)" 0.1 0.0 0.0 1.9 0.0 0.4 0.2 0.0 0.0 0.3 0.0 0.6 0.6 0.5 0.0 0.6 0.4 0.6 0.6 0.0 0.0 0.4 0.2 1.0 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.2 1.1 0.0 0.2 0.1 0.1 0.1 0.8 0.1 0.1 2.3 0.6 0.1 0.0 22.8 0.2 0.4 4.5 1.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 6.0 0.0 2.9 0.0 35.2 18.3 0.0 0.1 31.3 18.7 0.1 3.8 0.1 10.3 59.6 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 TRAV23DV6 "TCRAV17S1, TRAV23/DV6" ENSG00000211803 "T cell receptor alpha variable 23/delta variable 6" A0A075B6W5 14 22086407-22086961 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 26.3" "Cell type enriched" "Detected in single" 20 "T-cells: 4.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 79.3;naive CD4 T-cell: 85.6;T-reg: 65.6" "Lineage enriched" "Detected in many" 56 "T-cells: 85.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.79e-3)" "unprognostic (2.91e-2)" "unprognostic (2.01e-1)" "unprognostic (2.69e-1)" "unprognostic (2.66e-2)" "unprognostic (2.20e-2)" "unprognostic (1.19e-3)" "unprognostic (3.91e-2)" "unprognostic (1.04e-2)" "unprognostic (1.79e-1)" "unprognostic (2.24e-2)" "unprognostic (4.56e-3)" "unprognostic (1.34e-1)" "unprognostic (4.47e-2)" "unprognostic (7.44e-2)" "unprognostic (1.33e-1)" 0.5 0.1 0.0 6.4 0.0 1.1 0.5 0.0 0.0 0.5 0.0 1.2 2.1 0.2 0.0 1.0 0.5 1.3 0.3 0.0 0.0 0.1 0.5 1.8 10.3 0.0 0.1 1.3 0.0 0.1 0.0 0.0 0.0 0.6 1.8 0.0 0.5 0.1 0.1 0.1 1.0 0.5 0.0 3.3 2.2 0.0 0.0 26.3 0.6 0.0 10.8 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 2.0 0.0 3.2 0.0 79.3 19.6 0.0 0.1 85.6 21.4 1.5 0.1 0.0 0.0 65.6 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 TRAV24 ENSG00000211805 "T cell receptor alpha variable 24" A0A0B4J272 14 22105343-22105846 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 21.4" "Cell type enriched" "Detected in single" 11 "T-cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 24 "memory CD4 T-cell: 24.4;memory CD8 T-cell: 47.5;naive CD4 T-cell: 22.4;naive CD8 T-cell: 66.5;T-reg: 40.9" "Lineage enriched" "Detected in single" 244 "T-cells: 66.5" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.96e-3)" "unprognostic (2.05e-3)" "unprognostic (3.76e-2)" "unprognostic (1.79e-4)" "unprognostic (5.42e-2)" "unprognostic (1.04e-1)" "unprognostic (7.79e-3)" "unprognostic (3.31e-1)" "unprognostic (1.05e-1)" "unprognostic (2.47e-5)" "unprognostic (3.62e-2)" "unprognostic (3.91e-2)" "unprognostic (1.44e-2)" 0.2 0.0 0.0 3.8 0.3 0.4 0.2 0.0 0.3 0.2 0.0 0.6 1.0 0.2 0.0 0.0 0.6 0.9 0.0 0.0 0.2 0.0 1.0 1.4 7.4 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.0 0.0 0.6 0.0 0.0 0.0 1.2 0.7 0.0 2.3 1.7 0.0 0.6 21.4 0.1 0.5 4.5 1.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.7 0.1 24.4 47.5 0.0 0.0 22.4 66.5 0.2 0.0 0.1 0.2 40.9 10.0 0.0 0.3 0.0 0.3 0.0 0.2 0.2 0.5 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 TRAV25 "TCRAV25S1, TCRAV32S1" ENSG00000211806 "T cell receptor alpha variable 25" A0A0B4J276 14 22112347-22113031 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 15.2" "Cell type enriched" "Detected in single" 6 "T-cells: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 63 "memory CD4 T-cell: 33.5;memory CD8 T-cell: 20.9;naive CD4 T-cell: 32.6;naive CD8 T-cell: 22.5;T-reg: 49.4" "Lineage enriched" "Detected in single" 404 "T-cells: 49.4" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (9.50e-3)" "unprognostic (1.49e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-5)" "unprognostic (6.65e-3)" "unprognostic (7.53e-3)" "unprognostic (7.30e-3)" "unprognostic (1.69e-1)" "unprognostic (2.04e-1)" "unprognostic (3.52e-3)" "unprognostic (9.55e-2)" "unprognostic (4.17e-2)" "unprognostic (1.17e-1)" "unprognostic (3.74e-1)" 0.1 0.0 0.0 2.7 0.1 0.3 0.5 0.0 0.2 0.1 0.0 0.8 0.8 0.3 0.6 0.2 0.2 0.5 0.0 0.0 0.1 0.2 0.1 1.5 8.7 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.0 0.2 0.1 0.7 0.3 0.0 2.3 1.7 0.0 0.1 15.2 0.1 0.0 7.7 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 33.5 20.9 0.0 0.0 32.6 22.5 0.1 0.0 0.0 0.0 49.4 7.4 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 TRAV26-1 ENSG00000211807 "T cell receptor alpha variable 26-1" A0A087WT03 14 22123318-22124285 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 14.0" "Cell type enriched" "Detected in single" 5 "T-cells: 3.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 37.4;naive CD4 T-cell: 39.7;T-reg: 55.8" "Lineage enriched" "Detected in single" 69 "T-cells: 55.8" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.36e-3)" "unprognostic (1.33e-5)" "unprognostic (1.21e-2)" "unprognostic (3.60e-2)" "unprognostic (1.50e-3)" "unprognostic (1.08e-2)" "unprognostic (4.89e-2)" "unprognostic (1.99e-1)" "unprognostic (4.67e-4)" "unprognostic (3.93e-3)" "unprognostic (3.28e-1)" "unprognostic (4.01e-5)" "unprognostic (1.63e-1)" "unprognostic (1.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-2)" 0.1 0.1 0.0 2.9 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.8 0.5 0.1 0.0 0.4 0.1 0.9 0.0 0.0 0.0 0.1 0.2 1.0 8.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.2 0.0 0.0 0.1 1.1 0.0 0.0 2.6 1.6 0.0 0.0 14.0 0.1 0.0 6.2 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 1.2 0.0 37.4 9.6 0.0 0.0 39.7 12.5 0.4 0.0 0.1 0.0 55.8 7.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 TRAV26-2 "TCRAV26S2, TCRAV4S1, TRAV262" ENSG00000211812 "T cell receptor alpha variable 26-2" A0A0B4J265 14 22202583-22203368 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 30 "lymphoid tissue: 41.5" "Cell type enriched" "Detected in single" 11 "T-cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 35 "memory CD4 T-cell: 52.8;memory CD8 T-cell: 80.5;naive CD4 T-cell: 50.9;naive CD8 T-cell: 36.8;T-reg: 66.3" "Lineage enriched" "Detected in single" 121 "T-cells: 80.5" "Cell line enriched" "Detected in single" 122 "HDLM-2: 12.2" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.57e-5)" "unprognostic (1.82e-1)" "unprognostic (2.19e-1)" "unprognostic (6.76e-4)" "unprognostic (8.84e-5)" "unprognostic (4.51e-2)" "unprognostic (2.10e-2)" "unprognostic (8.91e-3)" "unprognostic (9.24e-2)" "unprognostic (2.61e-1)" "unprognostic (1.66e-2)" "unprognostic (1.42e-1)" "unprognostic (7.76e-3)" "unprognostic (3.41e-1)" "unprognostic (5.19e-2)" 0.1 0.0 0.1 4.6 0.0 0.3 0.2 0.0 0.1 0.0 0.0 1.1 0.6 0.0 0.0 0.5 0.1 1.0 0.0 0.1 0.0 0.1 0.9 1.3 9.9 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.3 0.1 0.0 0.0 0.8 0.3 0.0 1.9 1.0 0.1 0.2 41.5 0.1 0.6 7.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.6 0.1 0.9 0.0 52.8 80.5 0.0 0.1 50.9 36.8 0.6 0.0 0.1 0.0 66.3 18.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 TRAV27 ENSG00000211809 "T cell receptor alpha variable 27" A0A087WT01 14 22147995-22148633 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 19.8" "Cell type enriched" "Detected in some" 4 "T-cells: 4.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "memory CD4 T-cell: 51.6;memory CD8 T-cell: 58.9;naive CD4 T-cell: 60.4;naive CD8 T-cell: 59.1;T-reg: 81.9" "Lineage enriched" "Detected in many" 63 "T-cells: 81.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.86e-3)" "unprognostic (1.66e-2)" "unprognostic (4.15e-2)" "unprognostic (2.78e-4)" "unprognostic (1.61e-1)" "unprognostic (2.21e-3)" "unprognostic (3.13e-1)" "unprognostic (8.30e-2)" "unprognostic (1.12e-2)" "unprognostic (2.07e-2)" "unprognostic (6.61e-2)" "unprognostic (2.14e-1)" "unprognostic (1.75e-4)" "unprognostic (3.45e-1)" "unprognostic (3.91e-2)" "unprognostic (1.68e-1)" "unprognostic (3.12e-3)" 0.1 0.0 0.0 2.3 0.0 0.4 0.1 0.0 0.0 0.6 0.0 0.6 0.3 0.2 0.0 0.4 0.3 0.2 0.1 0.0 0.0 0.1 0.1 0.7 5.0 0.1 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.2 1.5 0.0 0.2 0.0 0.2 0.2 0.7 0.0 0.0 1.7 0.9 0.0 0.1 19.8 0.1 0.0 5.6 1.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.5 0.0 3.2 0.2 51.6 58.9 0.0 0.0 60.4 59.1 1.0 1.3 0.1 0.3 81.9 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 TRAV29DV5 TRAV29/DV5 ENSG00000211810 "T cell receptor alpha variable 29/delta variable 5" P04437 14 22163238-22163870 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 26.6" "Cell type enriched" "Detected in some" 5 "T-cells: 13.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 20 "memory CD4 T-cell: 99.2;memory CD8 T-cell: 126.3;naive CD4 T-cell: 105.5;naive CD8 T-cell: 66.4;T-reg: 123.9" "Lineage enriched" "Detected in single" 129 "T-cells: 126.3" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.25e-4)" "unprognostic (3.20e-3)" "unprognostic (4.50e-2)" "unprognostic (8.49e-4)" "unprognostic (3.24e-3)" "unprognostic (9.16e-2)" "unprognostic (2.73e-1)" "unprognostic (4.17e-3)" "unprognostic (4.47e-2)" "unprognostic (3.81e-1)" "unprognostic (1.03e-1)" "unprognostic (5.11e-4)" "unprognostic (7.53e-2)" "unprognostic (4.69e-2)" "unprognostic (9.86e-2)" "unprognostic (7.28e-2)" 0.2 0.0 0.0 4.7 0.0 0.8 0.3 0.0 0.1 0.2 0.0 1.3 1.7 0.1 0.4 0.8 0.5 0.9 0.3 0.0 0.0 0.2 0.5 1.3 11.8 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.3 0.2 0.0 0.0 1.8 0.2 0.0 4.7 2.0 0.1 0.1 26.6 0.1 0.0 11.7 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 5.1 0.2 2.5 0.1 99.2 126.3 0.1 0.2 105.5 66.4 0.9 0.2 0.2 0.2 123.9 35.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 TRAV3 ENSG00000211777 "T cell receptor alpha variable 3" A0A0B4J244 14 21723713-21724321 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 10.1" "Cell type enriched" "Detected in some" 4 "T-cells: 6.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 48.8;memory CD8 T-cell: 33.6;naive CD4 T-cell: 51.2;naive CD8 T-cell: 47.8;T-reg: 112.7" "Lineage enriched" "Detected in single" 144 "T-cells: 112.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.32e-3)" "unprognostic (4.61e-4)" "unprognostic (2.50e-1)" "unprognostic (6.25e-3)" "unprognostic (7.75e-2)" "unprognostic (8.35e-4)" "unprognostic (8.65e-3)" "unprognostic (4.31e-3)" "unprognostic (2.88e-3)" "unprognostic (4.24e-3)" "unprognostic (5.27e-2)" "unprognostic (3.35e-1)" "unprognostic (1.91e-4)" "unprognostic (1.67e-1)" "unprognostic (6.61e-2)" "unprognostic (9.32e-2)" "unprognostic (1.08e-1)" 0.2 0.2 0.0 2.9 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.5 0.1 0.2 0.6 0.5 0.0 0.0 0.1 0.2 0.8 7.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.8 0.0 0.2 0.0 0.0 0.3 1.3 0.0 0.0 2.0 1.0 0.3 0.4 10.1 0.1 0.1 5.7 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 14.3 0.0 48.8 33.6 0.1 0.1 51.2 47.8 0.7 0.1 0.0 0.0 112.7 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.0 0.0 0.0 6.7 0.0 0.0 0.0 TRAV30 ENSG00000259092 "T cell receptor alpha variable 30" A0A087WSZ9 14 22168429-22168988 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 13.7" "Cell type enriched" "Detected in single" 11 "T-cells: 2.2" "Cancer enriched" "Detected in many" 6 "renal cancer: 11.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "memory CD4 T-cell: 23.4;memory CD8 T-cell: 21.4;naive CD4 T-cell: 35.5;naive CD8 T-cell: 22.8;T-reg: 42.3" "Lineage enriched" "Detected in many" 28 "T-cells: 42.3" "Group enriched" "Detected in some" 14 "HDLM-2: 13.7;HHSteC: 11.4" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.98e-2)" "unprognostic (1.18e-1)" "unprognostic (2.34e-2)" "unprognostic (2.37e-2)" "unprognostic (3.75e-3)" "unprognostic (3.51e-1)" "unprognostic (2.35e-2)" "unprognostic (3.56e-2)" "unprognostic (2.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.57e-1)" "unprognostic (4.17e-2)" "unprognostic (3.85e-3)" "unprognostic (8.04e-3)" 0.1 0.0 0.0 1.5 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.8 1.4 0.8 0.0 0.2 1.7 0.4 0.0 0.1 0.0 2.1 2.0 0.9 6.4 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.5 0.0 0.4 0.8 0.0 0.0 1.1 0.0 0.0 1.6 0.5 0.0 0.1 13.7 0.0 0.3 3.7 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.2 0.1 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 1.1 0.0 0.8 0.0 23.4 21.4 0.2 0.0 35.5 22.8 1.4 0.0 0.0 0.2 42.3 11.6 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 TRAV34 "TCRAV26S1, TCRAV34S1" ENSG00000211813 "T cell receptor alpha variable 34" A0A0B4J273 14 22207522-22208129 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 19 "lymphoid tissue: 13.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 71 "memory CD4 T-cell: 9.9;memory CD8 T-cell: 4.5;naive CD4 T-cell: 14.0;naive CD8 T-cell: 5.0;T-reg: 16.9" "Lineage enriched" "Detected in single" 169 "T-cells: 16.9" "Cell line enriched" "Detected in single" 111 "HDLM-2: 59.2" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.61e-2)" "unprognostic (2.36e-4)" "unprognostic (1.24e-3)" "unprognostic (5.78e-2)" "unprognostic (1.18e-1)" "unprognostic (3.68e-2)" 0.0 0.0 0.1 0.9 0.0 0.0 0.2 0.1 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 2.9 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.5 0.0 0.3 13.3 0.0 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.9 4.5 0.0 0.0 14.0 5.0 0.0 0.0 0.0 0.0 16.9 2.6 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.5 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 TRAV36DV7 TRAV36/DV7 ENSG00000211815 "T cell receptor alpha variable 36/delta variable 7" A0A075B6V5 14 22226746-22227254 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 18 "lymphoid tissue: 27.5" "Cell type enriched" "Detected in single" 4 "T-cells: 2.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 29.2;memory CD8 T-cell: 21.9;naive CD4 T-cell: 37.6;naive CD8 T-cell: 23.0;T-reg: 50.1" "Lineage enriched" "Detected in many" 13 "T-cells: 50.1" "Group enriched" "Detected in some" 11 "Daudi: 1.4;HL-60: 3.3" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.67e-3)" "unprognostic (1.25e-2)" "unprognostic (1.81e-2)" "unprognostic (2.74e-2)" "unprognostic (7.69e-2)" "unprognostic (2.39e-6)" "unprognostic (8.10e-2)" "unprognostic (9.54e-2)" "unprognostic (3.13e-1)" "unprognostic (2.44e-2)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (4.62e-5)" "unprognostic (1.52e-1)" "unprognostic (2.91e-2)" "unprognostic (1.11e-1)" "unprognostic (4.17e-4)" 0.2 0.0 0.0 2.1 0.0 1.3 0.0 0.1 0.0 0.2 0.0 0.8 0.3 0.0 0.0 0.3 0.2 1.0 0.4 0.0 0.0 0.0 0.1 1.5 10.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 1.6 0.6 0.1 0.1 27.5 0.1 0.0 5.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.9 1.6 0.0 0.0 1.4 29.2 21.9 0.0 0.1 37.6 23.0 0.3 0.0 0.0 0.0 50.1 9.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 TRAV38-1 "TCRAV14S2, TCRAV38S1, TRAV381" ENSG00000211816 "T cell receptor alpha variable 38-1" A0A0B4J264 14 22271968-22272563 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "lymphoid tissue: 13.9" "Group enriched" "Detected in some" 13 "Gastric mucus-secreting cells: 1.1;T-cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 31 "memory CD4 T-cell: 41.2;memory CD8 T-cell: 21.9;naive CD4 T-cell: 46.4;naive CD8 T-cell: 29.2;T-reg: 71.5" "Lineage enriched" "Detected in single" 218 "T-cells: 71.5" "Cell line enriched" "Detected in single" 15 "HDLM-2: 6.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (5.06e-3)" "unprognostic (1.04e-2)" "unprognostic (1.03e-1)" "unprognostic (2.99e-3)" "unprognostic (7.49e-2)" "unprognostic (1.21e-1)" "unprognostic (1.14e-1)" "unprognostic (5.75e-1)" "unprognostic (1.25e-2)" "unprognostic (2.46e-1)" "unprognostic (2.76e-2)" "unprognostic (2.26e-1)" 0.2 0.0 0.0 3.0 0.0 0.3 0.2 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.7 13.9 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.2 0.0 0.2 0.1 0.7 0.0 0.0 2.1 1.1 0.1 0.1 13.7 0.0 0.0 7.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.8 0.1 41.2 21.9 0.0 0.0 46.4 29.2 0.3 0.0 0.2 0.2 71.5 15.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 TRAV38-2DV8 "hADV38S2, TCRAV14S1, TRAV38-2/DV8, TRAV382DV8" ENSG00000211817 "T cell receptor alpha variable 38-2/delta variable 8" A0JD32 14 22281105-22281748 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 34.2" "Group enriched" "Detected in some" 4 "Gastric mucus-secreting cells: 3.1;T-cells: 3.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.3" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 182.9;memory CD8 T-cell: 113.3;naive CD4 T-cell: 152.6;naive CD8 T-cell: 96.6;T-reg: 227.6" "Lineage enriched" "Detected in many" 9 "T-cells: 227.6" "Cell line enriched" "Detected in single" 16 "HDLM-2: 1.6" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" 0.4 0.4 0.2 4.2 0.2 0.7 0.6 0.1 0.3 0.8 0.0 1.1 1.5 0.5 0.0 0.4 0.5 1.5 0.1 0.2 0.1 0.5 0.8 1.3 12.4 0.2 1.3 0.1 0.0 0.1 0.0 0.2 0.3 1.2 1.9 0.0 0.4 0.3 0.0 0.1 1.2 0.1 0.1 2.9 1.4 0.2 0.3 34.2 0.2 0.6 8.0 3.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.1 33.2 0.1 0.2 0.3 182.9 113.3 0.2 0.3 152.6 96.6 2.4 0.2 0.4 24.5 227.6 57.7 0.2 0.2 0.1 0.3 0.2 0.1 0.2 1.3 0.3 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 TRAV39 "TCRAV27S1, TCRAV39S1" ENSG00000211818 "T cell receptor alpha variable 39" A0A0B4J263 14 22304054-22304553 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 16 "lymphoid tissue: 65.2" "Cell type enhanced" "Detected in single" "T-cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 33.2;memory CD8 T-cell: 27.1;naive CD4 T-cell: 35.8;naive CD8 T-cell: 23.6;T-reg: 36.7" "Lineage enriched" "Detected in many" 7 "T-cells: 36.7" "Cell line enhanced" "Detected in single" "MCF7: 1.1" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 58: T-cells - T-cell receptor" "unprognostic (9.69e-3)" "unprognostic (4.53e-3)" "unprognostic (8.90e-2)" "unprognostic (6.16e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-2)" "unprognostic (5.71e-2)" "unprognostic (8.03e-3)" "unprognostic (3.17e-1)" "unprognostic (8.97e-2)" "unprognostic (8.96e-2)" "unprognostic (2.29e-1)" "unprognostic (6.55e-8)" "unprognostic (7.91e-2)" "unprognostic (5.25e-2)" "unprognostic (4.51e-2)" "unprognostic (3.56e-1)" 0.6 0.3 0.3 2.8 0.2 0.2 0.1 0.2 0.2 0.2 0.1 0.5 1.0 0.7 0.0 0.1 0.2 0.5 0.6 0.6 0.2 1.8 0.0 3.9 7.7 0.2 0.2 0.3 0.0 0.0 0.0 0.2 0.2 0.8 1.2 0.0 0.1 0.6 0.0 0.2 0.4 0.3 0.2 1.9 0.7 1.3 0.3 65.2 0.0 0.6 6.0 1.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 33.2 27.1 0.0 0.0 35.8 23.6 0.0 0.0 0.0 5.3 36.7 8.6 0.3 0.2 0.2 0.2 0.6 0.2 0.2 0.2 0.2 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 TRAV4 "TCRAV20S1, TCRAV4S1" ENSG00000211778 "T cell receptor alpha variable 4" A0A0B4J268 14 21736152-21736982 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 37.9" "Cell type enriched" "Detected in some" 8 "T-cells: 8.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 70 "MAIT T-cell: 66.1;memory CD4 T-cell: 81.9;memory CD8 T-cell: 124.0;naive CD4 T-cell: 77.1;naive CD8 T-cell: 81.0;T-reg: 167.9" "Lineage enriched" "Detected in many" 118 "T-cells: 167.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.13e-2)" "unprognostic (4.08e-3)" "unprognostic (1.02e-1)" "unprognostic (2.39e-4)" "unprognostic (5.20e-3)" "unprognostic (1.18e-4)" "unprognostic (1.34e-2)" "unprognostic (5.48e-2)" "unprognostic (7.19e-3)" "unprognostic (2.48e-3)" "unprognostic (8.68e-2)" "unprognostic (2.82e-1)" "unprognostic (1.37e-4)" "unprognostic (1.65e-1)" "unprognostic (3.23e-1)" "unprognostic (2.89e-1)" "unprognostic (6.49e-2)" 0.4 0.3 0.0 7.7 0.0 1.3 1.1 0.0 0.4 1.1 0.0 1.8 1.7 0.3 0.0 1.1 0.6 2.8 0.5 0.1 0.0 0.2 0.6 2.4 17.4 0.3 0.4 0.2 0.5 0.1 0.0 0.1 0.2 1.2 2.1 0.0 0.8 0.1 0.0 0.4 3.3 0.4 0.1 5.4 2.4 0.3 0.2 37.9 0.3 0.0 14.2 2.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.6 0.1 66.1 0.1 81.9 124.0 0.1 0.1 77.1 81.0 1.4 0.4 0.5 0.4 167.9 25.2 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.4 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 TRAV40 "TCRAV31S1, TCRAV40S1" ENSG00000211819 "T cell receptor alpha variable 40" A0A0B4J280 14 22314490-22314919 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 24 "lymphoid tissue: 9.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory CD4 T-cell: 5.4;memory CD8 T-cell: 3.2;naive CD4 T-cell: 4.8;naive CD8 T-cell: 4.4;T-reg: 6.4" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 9.3 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.4 3.2 0.0 0.0 4.8 4.4 0.0 0.0 0.0 0.0 6.4 1.4 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TRAV41 "TCRAV19S1, TCRAV41S1" ENSG00000211820 "T cell receptor alpha variable 41" A0A0B4J266 14 22320188-22320691 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 39 "lymphoid tissue: 107.8" "Cell type enriched" "Detected in single" 7 "T-cells: 2.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 77.1;naive CD4 T-cell: 74.1;T-reg: 71.1" "Lineage enriched" "Detected in many" 46 "T-cells: 77.1" "Cell line enriched" "Detected in some" 60 "HDLM-2: 136.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.25e-3)" "unprognostic (1.98e-2)" "unprognostic (1.17e-1)" "unprognostic (2.30e-1)" "unprognostic (1.94e-1)" "unprognostic (8.89e-3)" "unprognostic (1.56e-1)" "unprognostic (6.27e-2)" "unprognostic (2.22e-1)" "unprognostic (1.99e-2)" "unprognostic (6.89e-3)" "unprognostic (3.33e-2)" "unprognostic (1.49e-3)" "unprognostic (1.24e-1)" "unprognostic (3.37e-2)" "unprognostic (8.34e-3)" "unprognostic (1.45e-1)" 0.1 0.0 0.7 5.7 1.1 0.4 0.4 0.7 1.8 0.1 0.6 1.0 1.0 0.5 0.0 0.7 0.1 1.3 0.0 0.9 0.8 0.0 0.3 2.7 16.1 1.2 0.9 0.0 0.0 0.1 0.0 0.0 0.9 0.3 1.6 0.0 0.0 0.1 0.3 0.1 0.8 0.7 0.7 4.1 1.2 0.1 0.8 107.8 0.2 0.0 12.6 1.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 3.3 0.8 0.3 0.0 77.1 19.1 0.0 0.0 74.1 31.0 1.6 0.1 0.1 0.0 71.1 18.1 0.7 1.1 0.7 1.8 0.9 0.8 1.2 0.9 0.9 0.7 0.8 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 TRAV5 ENSG00000211779 "T cell receptor alpha variable 5" A0A0B4J249 14 21749178-21749705 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 12.9" "Cell type enriched" "Detected in some" 5 "T-cells: 7.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 52 "MAIT T-cell: 24.7;memory CD4 T-cell: 49.5;memory CD8 T-cell: 77.3;naive CD4 T-cell: 39.9;naive CD8 T-cell: 74.0;T-reg: 81.4" "Lineage enriched" "Detected in many" 73 "T-cells: 81.4" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.04e-3)" "unprognostic (2.62e-3)" "unprognostic (1.33e-1)" "unprognostic (1.69e-2)" "unprognostic (6.26e-5)" "unprognostic (3.58e-1)" "unprognostic (8.15e-2)" "unprognostic (5.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.12e-1)" "unprognostic (3.11e-2)" "unprognostic (8.38e-6)" "unprognostic (2.28e-1)" "unprognostic (1.62e-1)" "unprognostic (1.78e-1)" "unprognostic (1.70e-2)" 0.1 0.4 0.0 3.6 0.0 0.5 0.7 0.0 0.2 0.3 0.5 1.0 0.5 0.7 0.0 0.3 0.1 2.7 0.2 0.1 0.0 0.2 0.8 1.1 12.9 0.3 0.2 0.3 0.6 0.0 0.0 0.0 0.1 2.1 1.6 0.0 2.6 0.3 0.0 0.0 2.7 0.8 0.0 4.6 1.8 0.1 0.1 11.5 0.8 0.8 7.6 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 1.0 0.5 24.7 0.2 49.5 77.3 0.1 0.1 39.9 74.0 1.1 0.0 0.2 0.3 81.4 17.9 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.7 0.0 0.0 0.0 TRAV6 TCRAV5S1 ENSG00000211780 "T cell receptor alpha variable 6" A0A075B6T7 14 21768489-21769080 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 11.2" "Group enriched" "Detected in some" 7 "Gastric mucus-secreting cells: 1.1;T-cells: 3.4" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 70 "MAIT T-cell: 17.1;memory CD4 T-cell: 33.7;memory CD8 T-cell: 19.0;naive CD4 T-cell: 26.3;naive CD8 T-cell: 16.2;T-reg: 59.6" "Lineage enriched" "Detected in single" 146 "T-cells: 59.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.44e-2)" "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (1.78e-1)" "unprognostic (3.49e-4)" "unprognostic (3.25e-1)" "unprognostic (2.49e-2)" "unprognostic (2.79e-1)" "unprognostic (8.90e-3)" "unprognostic (2.05e-1)" "unprognostic (1.81e-1)" "unprognostic (2.87e-5)" "unprognostic (1.32e-1)" "unprognostic (2.95e-2)" "unprognostic (3.59e-1)" "unprognostic (1.24e-2)" 0.1 0.0 0.0 2.4 0.0 0.6 0.5 0.0 0.0 0.1 0.0 1.0 0.3 0.1 0.6 0.6 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.8 5.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.7 0.0 0.2 0.2 0.0 0.0 2.3 0.0 0.0 2.7 0.8 0.1 0.4 11.2 0.1 0.0 4.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 17.1 0.2 33.7 19.0 0.0 0.1 26.3 16.2 0.4 0.0 0.0 0.0 59.6 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 TRAV7 ENSG00000211781 "T cell receptor alpha variable 7" A0A075B6U4 14 21782993-21783503 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRAV8-1 ENSG00000211782 "T cell receptor alpha variable 8-1" A0A0A6YYK1 14 21797287-21797886 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 11.8" "Cell type enriched" "Detected in single" 9 "T-cells: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 43 "MAIT T-cell: 14.2;memory CD4 T-cell: 39.5;memory CD8 T-cell: 20.6;naive CD4 T-cell: 37.6;naive CD8 T-cell: 16.3;T-reg: 54.4" "Lineage enriched" "Detected in single" 77 "T-cells: 54.4" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (8.53e-3)" "unprognostic (1.98e-2)" "unprognostic (5.44e-2)" "unprognostic (1.34e-2)" "unprognostic (4.86e-4)" "unprognostic (2.84e-3)" "unprognostic (8.19e-3)" "unprognostic (1.90e-2)" "unprognostic (6.27e-3)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" "unprognostic (6.54e-5)" "unprognostic (2.60e-1)" "unprognostic (2.31e-1)" "unprognostic (3.86e-1)" "unprognostic (5.72e-2)" 0.1 0.0 0.0 3.7 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.7 0.6 0.2 0.2 0.7 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.8 6.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.6 0.0 0.1 0.2 0.7 0.0 0.0 1.7 0.5 0.2 0.0 11.8 0.0 0.0 4.7 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 14.2 0.0 39.5 20.6 0.1 0.1 37.6 16.3 0.7 0.0 0.0 0.1 54.4 8.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 TRAV8-2 ENSG00000211786 "T cell receptor alpha variable 8-2" A0A0B4J237 14 21846537-21847221 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 24.1" "Cell type enriched" "Detected in some" 9 "T-cells: 10.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 99 "MAIT T-cell: 59.1;memory CD4 T-cell: 143.4;memory CD8 T-cell: 81.1;naive CD4 T-cell: 143.2;naive CD8 T-cell: 80.1;T-reg: 190.6" "Lineage enriched" "Detected in many" 184 "T-cells: 190.6" "Cell line enriched" "Detected in single" 6 "JURKAT: 1.9" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (5.88e-3)" "unprognostic (9.98e-4)" "unprognostic (2.31e-2)" "unprognostic (2.23e-2)" "unprognostic (9.88e-5)" "unprognostic (1.94e-3)" "unprognostic (7.22e-3)" "unprognostic (9.30e-3)" "unprognostic (2.82e-3)" "unprognostic (1.39e-1)" "unprognostic (1.69e-1)" "unprognostic (7.57e-5)" "unprognostic (1.86e-1)" "unprognostic (5.00e-2)" "unprognostic (6.66e-2)" "unprognostic (1.02e-1)" 0.3 0.1 0.0 3.2 0.0 1.9 0.2 0.0 0.0 0.2 0.0 0.7 1.1 0.2 1.6 0.5 0.2 1.4 0.1 0.0 0.0 2.7 0.2 1.2 14.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.1 0.0 0.4 0.0 0.0 0.4 1.3 0.1 0.0 4.1 1.3 0.3 0.0 24.1 0.3 0.0 6.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 1.0 1.1 0.1 59.1 0.2 143.4 81.1 0.3 0.3 143.2 80.1 0.7 0.2 0.2 0.1 190.6 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.7 0.0 0.0 0.0 TRAV8-3 ENSG00000211787 "T cell receptor alpha variable 8-3" A0A0A6YYJ7 14 21852558-21853006 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 71.1" "Cell type enriched" "Detected in single" 7 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 138.2;T-reg: 153.1" "Lineage enriched" "Detected in many" 47 "T-cells: 153.1" "Cell line enriched" "Detected in single" 6 "JURKAT: 2.9" "Low region specificity" "Detected in single" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.74e-4)" "unprognostic (5.25e-5)" "unprognostic (8.88e-4)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (9.64e-5)" "unprognostic (8.20e-2)" "unprognostic (1.25e-2)" "unprognostic (1.38e-2)" "unprognostic (6.44e-2)" "unprognostic (2.13e-2)" "unprognostic (1.46e-1)" "unprognostic (2.66e-5)" "unprognostic (2.99e-1)" "unprognostic (4.17e-2)" "unprognostic (1.04e-1)" "unprognostic (1.26e-2)" 0.6 0.0 0.2 6.5 0.3 3.8 2.9 0.0 1.2 2.3 0.0 3.0 2.4 0.8 16.8 1.6 8.9 5.7 0.4 0.3 0.0 0.7 1.2 3.8 40.2 0.0 0.0 0.5 0.0 0.1 0.0 0.6 0.0 1.9 4.7 0.0 2.0 0.7 0.3 0.8 2.7 1.0 0.0 9.1 2.7 3.1 0.0 71.1 0.9 1.1 30.2 6.8 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.4 1.2 0.1 29.7 0.1 106.6 48.4 0.3 0.6 138.2 77.0 3.2 0.2 0.3 0.9 153.1 34.6 0.2 0.3 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 TRAV8-4 ENSG00000211790 "T cell receptor alpha variable 8-4" P01737 14 21894433-21895030 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 20.8" "Cell type enriched" "Detected in single" 15 "T-cells: 4.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 184.9;memory CD8 T-cell: 101.6;naive CD4 T-cell: 154.6;naive CD8 T-cell: 74.5;T-reg: 235.1" "Lineage enriched" "Detected in many" 49 "T-cells: 235.1" "Cell line enriched" "Detected in single" 1440 "JURKAT: 405.7" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.41e-4)" "unprognostic (1.74e-3)" "unprognostic (2.29e-2)" "unprognostic (1.14e-4)" "unprognostic (3.47e-4)" "unprognostic (5.06e-2)" "unprognostic (1.42e-2)" "unprognostic (5.10e-4)" "unprognostic (4.24e-3)" "unprognostic (1.41e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-3)" "unprognostic (1.42e-1)" "unprognostic (3.80e-2)" "unprognostic (2.60e-1)" "unprognostic (5.58e-2)" 0.3 0.0 0.0 6.5 0.0 0.6 0.5 0.0 0.1 0.3 0.3 1.0 0.8 0.0 0.2 0.1 0.2 0.8 0.2 0.0 0.0 0.2 0.3 0.8 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.5 0.0 0.3 0.1 0.1 0.6 1.7 0.3 0.0 2.9 1.5 0.2 0.0 20.8 0.2 0.1 7.6 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 405.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.1 1.4 0.2 24.1 1.9 184.9 101.6 0.1 0.2 154.6 74.5 4.7 0.3 0.3 0.3 235.1 45.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 TRAV8-6 ENSG00000211795 "T cell receptor alpha variable 8-6" A0A0B4J262 14 21978459-21979120 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 24.7" "Group enriched" "Detected in some" 19 "Spermatocytes: 1.2;Spermatogonia: 1.5;T-cells: 3.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 89.3;memory CD8 T-cell: 64.2;naive CD4 T-cell: 92.6;naive CD8 T-cell: 38.7;T-reg: 125.0" "Lineage enriched" "Detected in many" 45 "T-cells: 125.0" "Cell line enriched" "Detected in single" 97 "JURKAT: 9.6" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.42e-2)" "unprognostic (9.23e-4)" "unprognostic (5.47e-3)" "unprognostic (1.27e-3)" "unprognostic (7.80e-2)" "unprognostic (7.74e-5)" "unprognostic (2.88e-3)" "unprognostic (5.41e-3)" "unprognostic (2.59e-3)" "unprognostic (2.24e-2)" "unprognostic (9.25e-2)" "unprognostic (2.92e-1)" "unprognostic (9.78e-5)" "unprognostic (4.65e-1)" "unprognostic (2.80e-2)" "unprognostic (1.94e-1)" "unprognostic (1.61e-3)" 0.2 0.0 0.0 3.0 0.0 0.8 0.8 0.0 0.0 0.4 0.0 0.9 0.7 0.3 0.7 0.3 0.3 2.0 0.2 0.0 0.0 0.3 0.3 1.4 10.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.2 0.1 0.1 0.2 1.3 0.4 0.1 2.9 1.5 0.4 0.0 24.7 0.1 0.1 8.2 1.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 17.9 0.2 89.3 64.2 0.1 0.1 92.6 38.7 2.8 0.1 0.1 0.2 125.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.5 0.0 0.0 0.0 3.2 0.0 0.0 0.0 TRAV8-7 ENSG00000211808 "T cell receptor alpha variable 8-7 (pseudogene)" 14 22132553-22133034 "Predicted intracellular proteins, T-cell receptor genes" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRAV9-1 ENSG00000211783 "T cell receptor alpha variable 9-1" A0A075B6T8 14 21811502-21811977 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRAV9-2 ENSG00000211793 "T cell receptor alpha variable 9-2" A0A087WT02 14 21941128-21941657 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 27.8" "Cell type enriched" "Detected in single" 6 "T-cells: 5.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 178.3;naive CD4 T-cell: 172.2;T-reg: 350.8" "Lineage enriched" "Detected in many" 78 "T-cells: 350.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.02e-3)" "unprognostic (2.04e-3)" "unprognostic (1.06e-1)" "unprognostic (1.25e-4)" "unprognostic (1.14e-5)" "unprognostic (1.37e-2)" "unprognostic (2.23e-2)" "unprognostic (5.98e-4)" "unprognostic (9.53e-3)" "unprognostic (1.92e-1)" "unprognostic (2.51e-1)" "unprognostic (9.00e-4)" "unprognostic (2.49e-1)" "unprognostic (4.28e-2)" "unprognostic (3.38e-1)" "unprognostic (2.56e-2)" 0.2 0.0 0.0 5.6 0.0 0.1 0.3 0.0 0.2 0.7 0.0 1.8 0.8 0.2 0.0 0.4 0.4 1.7 0.2 0.0 0.0 0.2 1.1 1.8 18.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.4 0.0 0.1 0.4 0.2 0.2 2.0 0.5 0.0 5.0 3.1 0.1 0.0 27.8 0.2 0.2 16.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.2 0.8 0.0 14.3 0.6 178.3 43.4 0.2 0.3 172.2 42.5 4.4 0.3 0.2 1.1 350.8 40.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 TRBV10-1 "TCRBV10S1, TCRBV12S2, TCRBV12S2A1T, TRBV101" ENSG00000211717 "T cell receptor beta variable 10-1" A0A0K0K1A3 7 142399860-142400377 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 13 "lymphoid tissue: 4.4" "Cell type enriched" "Detected in single" 4 "T-cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "MAIT T-cell: 3.2;memory CD4 T-cell: 4.7;memory CD8 T-cell: 3.0;naive CD4 T-cell: 6.2;naive CD8 T-cell: 2.6;T-reg: 9.5" "Lineage enriched" "Detected in single" 18 "T-cells: 9.5" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.41e-2)" "unprognostic (3.88e-1)" "unprognostic (2.85e-3)" 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.1 0.0 4.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 4.7 3.0 0.0 0.0 6.2 2.6 0.5 0.0 0.0 0.0 9.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 TRBV10-2 "TCRBV10S2, TCRBV12S3, TRBV102" ENSG00000229769 "T cell receptor beta variable 10-2" A0A0K0K1G8 7 142424965-142425465 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 2.7" "Cell type enriched" "Detected in single" 20 "T-cells: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 11.8;memory CD8 T-cell: 33.8;naive CD4 T-cell: 10.3;naive CD8 T-cell: 9.1;T-reg: 24.5" "Lineage enriched" "Detected in single" 338 "T-cells: 33.8" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.30e-3)" "unprognostic (5.71e-2)" "unprognostic (3.57e-2)" "unprognostic (5.26e-2)" "unprognostic (2.24e-5)" "unprognostic (2.97e-2)" "unprognostic (5.84e-2)" "unprognostic (2.77e-1)" "unprognostic (5.65e-1)" "unprognostic (2.55e-3)" "unprognostic (5.27e-2)" "unprognostic (3.55e-3)" "unprognostic (3.51e-1)" 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.2 0.7 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.5 0.0 0.0 2.7 0.4 0.2 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 1.4 0.0 11.8 33.8 0.0 0.0 10.3 9.1 0.0 0.0 0.0 0.0 24.5 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 TRBV10-3 "TCRBV10S3, TCRBV12S1A1N2, TRBV103" ENSG00000275791 "T cell receptor beta variable 10-3" A0A0K0K1G6 7 142544212-142544685 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 31 "lymphoid tissue: 88.6" "Group enriched" "Detected in some" 5 "Late spermatids: 1.7;T-cells: 5.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 160.1;T-reg: 203.1" "Lineage enriched" "Detected in single" 375 "T-cells: 203.1" "Cell line enriched" "Detected in single" 53 "MOLT-4: 49.7" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.61e-3)" "unprognostic (4.86e-3)" "unprognostic (2.44e-2)" "unprognostic (8.96e-3)" "unprognostic (3.16e-1)" "unprognostic (4.23e-6)" "unprognostic (9.84e-4)" "unprognostic (7.96e-2)" "unprognostic (4.05e-2)" "unprognostic (7.99e-4)" "unprognostic (1.52e-1)" "unprognostic (1.66e-1)" "unprognostic (9.59e-6)" "unprognostic (5.93e-2)" "unprognostic (1.69e-1)" "unprognostic (1.05e-1)" "unprognostic (1.80e-3)" 0.3 0.2 0.0 8.0 0.0 2.8 0.2 0.0 0.0 0.4 0.0 1.1 0.0 0.1 0.0 0.3 0.2 1.0 0.1 0.0 0.0 0.1 0.4 0.5 16.8 0.0 0.0 0.3 1.1 0.1 0.0 0.0 0.0 0.5 0.8 0.0 0.9 0.1 0.0 0.0 1.4 0.3 0.0 2.1 2.3 0.1 0.1 88.6 0.2 0.0 12.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.9 0.0 49.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.3 0.1 9.3 0.4 77.0 160.1 0.0 0.3 101.7 41.2 0.3 0.1 0.5 0.5 203.1 26.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 TRBV11-1 "TCRBV11S1, TCRBV21S1, TRBV111" ENSG00000211720 "T cell receptor beta variable 11-1" A0A0K0K1C0 7 142407672-142408136 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 28 "lymphoid tissue: 14.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "memory CD4 T-cell: 20.1;memory CD8 T-cell: 30.4;naive CD4 T-cell: 15.6;naive CD8 T-cell: 11.8;T-reg: 25.6" "Lineage enriched" "Detected in single" 99 "T-cells: 30.4" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (4.15e-1)" "unprognostic (1.40e-2)" "unprognostic (3.79e-2)" "unprognostic (6.13e-2)" "unprognostic (1.82e-1)" "unprognostic (7.44e-2)" "unprognostic (1.90e-1)" "unprognostic (5.18e-2)" "unprognostic (8.48e-2)" 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.5 3.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.0 0.9 0.3 0.0 0.0 14.3 0.1 0.0 3.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 20.1 30.4 0.0 0.0 15.6 11.8 0.3 0.0 0.0 0.0 25.6 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TRBV11-3 "TCRBV11S3, TCRBV21S2A2, TRBV113" ENSG00000276597 "T cell receptor beta variable 11-3" A0A5A6 7 142554836-142555318 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 31 "lymphoid tissue: 22.1" "Group enriched" "Detected in some" 20 "Gastric mucus-secreting cells: 1.5;T-cells: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "MAIT T-cell: 3.1;memory CD4 T-cell: 12.0;memory CD8 T-cell: 5.2;naive CD4 T-cell: 11.6;naive CD8 T-cell: 5.9;T-reg: 10.1" "Lineage enriched" "Detected in single" 120 "T-cells: 12.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.62e-3)" "unprognostic (9.92e-4)" "unprognostic (5.54e-2)" "unprognostic (1.05e-1)" "unprognostic (1.60e-3)" "unprognostic (3.30e-1)" "unprognostic (3.85e-2)" 0.0 0.0 0.0 1.5 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.3 0.6 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.7 0.4 0.0 0.0 22.1 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 3.1 0.0 12.0 5.2 0.0 0.0 11.6 5.9 0.0 0.0 0.0 0.0 10.1 2.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 TRBV12-3 "TCRBV12S3, TCRBV8S1, TRBV123" ENSG00000274752 "T cell receptor beta variable 12-3" P01733 7 142560423-142560931 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "lymphoid tissue: 61.0" "Group enriched" "Detected in some" 19 "Gastric mucus-secreting cells: 4.6;T-cells: 10.7" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "memory CD4 T-cell: 29.2;memory CD8 T-cell: 14.9;naive CD4 T-cell: 32.5;naive CD8 T-cell: 23.9;T-reg: 46.0" "Lineage enriched" "Detected in many" 11 "T-cells: 46.0" "Cell line enriched" "Detected in some" 339 "JURKAT: 1248.3" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (5.41e-3)" "unprognostic (9.35e-4)" "unprognostic (5.34e-3)" "unprognostic (1.39e-4)" "unprognostic (5.43e-6)" "unprognostic (1.97e-2)" "unprognostic (5.06e-2)" "unprognostic (7.76e-3)" "unprognostic (2.50e-2)" "unprognostic (7.32e-2)" "unprognostic (1.58e-1)" "unprognostic (9.57e-5)" "unprognostic (2.45e-1)" "unprognostic (1.76e-3)" "unprognostic (3.22e-1)" "unprognostic (2.70e-2)" 0.3 0.0 0.0 4.4 0.0 2.3 0.4 0.0 0.0 1.4 0.0 1.0 1.0 0.2 0.3 0.5 0.1 1.3 0.3 0.0 0.0 0.2 0.6 1.4 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 1.3 0.0 0.8 0.0 0.4 0.1 2.2 0.1 0.0 3.8 2.1 0.2 0.0 61.0 0.3 0.0 12.6 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.2 1.0 0.9 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.7 0.0 1248.3 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 4.0 0.0 0.0 0.5 0.1 1.2 0.0 29.2 14.9 0.0 0.0 32.5 23.9 1.0 0.0 0.0 0.0 46.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 TRBV12-4 "TCRBV12S4, TCRBV8S2A1T, TRBV124" ENSG00000276953 "T cell receptor beta variable 12-4" A0A0B4J2E0 7 142563740-142564245 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 44 "lymphoid tissue: 110.3" "Cell type enriched" "Detected in some" 5 "T-cells: 5.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 32 "memory CD4 T-cell: 28.6;memory CD8 T-cell: 38.8;naive CD4 T-cell: 39.7;naive CD8 T-cell: 33.7;T-reg: 54.4" "Lineage enriched" "Detected in single" 68 "T-cells: 54.4" "Cell line enriched" "Detected in some" 11 "LHCN-M2: 51.6" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.97e-4)" "unprognostic (1.20e-4)" "unprognostic (7.96e-2)" "unprognostic (1.32e-3)" "unprognostic (3.96e-4)" "unprognostic (1.20e-2)" "unprognostic (5.27e-3)" "unprognostic (1.50e-2)" "unprognostic (9.59e-4)" "unprognostic (1.53e-2)" "unprognostic (1.25e-1)" "unprognostic (8.22e-5)" "unprognostic (4.32e-2)" "unprognostic (5.32e-3)" "unprognostic (1.44e-1)" "unprognostic (5.08e-3)" 0.5 0.0 0.0 6.2 0.0 1.3 0.6 0.0 0.2 0.4 0.0 1.2 0.3 0.4 0.0 0.2 0.3 0.5 0.1 0.0 0.0 0.1 1.2 1.1 21.5 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.2 0.2 0.1 0.3 2.4 0.1 0.0 2.7 2.3 0.6 0.0 110.3 0.3 0.2 2.3 1.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.7 0.0 4.2 1.9 0.4 1.9 0.2 0.0 0.2 51.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 28.6 38.8 0.0 0.0 39.7 33.7 0.7 0.0 0.0 0.2 54.4 10.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 TRBV12-5 "TCRBV12S5, TCRBV8S3, TRBV125" ENSG00000275158 "T cell receptor beta variable 12-5" A0A1B0GX78 7 142580917-142581427 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 74 "lymphoid tissue: 48.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "memory CD4 T-cell: 4.8;naive CD4 T-cell: 8.3;naive CD8 T-cell: 8.7;T-reg: 9.8" "Lineage enriched" "Detected in single" 99 "T-cells: 9.8" "Cell line enhanced" "Detected in single" "Karpas-707: 1.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (5.12e-2)" "unprognostic (7.81e-2)" "unprognostic (2.53e-1)" "unprognostic (2.37e-3)" "unprognostic (2.74e-2)" "unprognostic (1.18e-1)" "unprognostic (1.55e-7)" "unprognostic (6.99e-2)" "unprognostic (2.00e-1)" "unprognostic (8.36e-2)" 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 48.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 1.0 0.0 0.0 8.3 8.7 0.0 0.0 0.0 0.0 9.8 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 TRBV13 "TCRBV13S1, TCRBV23S1A2T" ENSG00000276405 "T cell receptor beta variable 13" A0A0A6YYD4 7 142535809-142536292 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 20 "lymphoid tissue: 30.8" "Group enriched" "Detected in some" 4 "Erythroid cells: 2.5;Late spermatids: 2.5;T-cells: 4.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory CD4 T-cell: 7.9;memory CD8 T-cell: 13.3;naive CD4 T-cell: 11.5;naive CD8 T-cell: 21.0;T-reg: 20.9" "Lineage enriched" "Detected in single" 211 "T-cells: 21.0" "Cell line enriched" "Detected in some" 9 "MOLT-4: 40.6" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.74e-5)" "unprognostic (5.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.00e-1)" "unprognostic (5.71e-4)" "unprognostic (8.28e-2)" "unprognostic (7.17e-2)" "unprognostic (2.49e-2)" "unprognostic (1.17e-2)" "unprognostic (3.32e-1)" "unprognostic (1.19e-6)" "unprognostic (1.44e-1)" "unprognostic (3.46e-2)" "unprognostic (6.95e-3)" "unprognostic (7.87e-2)" 0.1 0.3 0.0 1.6 0.0 1.1 0.2 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.1 0.5 0.7 6.8 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 2.0 0.7 0.3 0.1 30.8 0.1 0.0 3.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 3.0 0.5 1.2 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.9 0.0 0.0 4.4 0.0 40.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 7.9 13.3 0.0 0.0 11.5 21.0 0.0 0.0 0.0 0.0 20.9 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 TRBV14 "TCRBV14S1, TCRBV16S1A1N1" ENSG00000275743 "T cell receptor beta variable 14" A0A5B0 7 142587868-142588359 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 46 "lymphoid tissue: 45.4" "Cell type enriched" "Detected in single" 11 "T-cells: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "memory CD4 T-cell: 20.2;memory CD8 T-cell: 24.6;naive CD4 T-cell: 21.6;naive CD8 T-cell: 19.5;T-reg: 27.1" "Lineage enriched" "Detected in single" 60 "T-cells: 27.1" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.70e-4)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (8.53e-4)" "unprognostic (3.16e-4)" "unprognostic (5.12e-2)" "unprognostic (6.14e-5)" "unprognostic (1.77e-1)" "unprognostic (9.00e-3)" "unprognostic (3.05e-1)" "unprognostic (3.30e-1)" "unprognostic (2.09e-3)" "unprognostic (8.25e-2)" "unprognostic (6.65e-3)" "unprognostic (4.82e-2)" "unprognostic (5.44e-2)" 0.3 0.0 0.0 2.1 0.0 0.9 0.1 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.4 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.6 4.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.3 0.0 0.9 0.0 0.0 1.3 0.5 0.1 0.0 45.4 0.1 0.0 5.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.1 0.0 2.2 0.0 20.2 24.6 0.0 0.2 21.6 19.5 0.4 0.0 0.0 0.0 27.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 TRBV15 "TCRBV15S1, TCRBV24S1A3T" ENSG00000276819 "T cell receptor beta variable 15" 7 142592928-142593473 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 67 "lymphoid tissue: 46.9" "Cell type enriched" "Detected in single" 27 "T-cells: 2.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 48 "MAIT T-cell: 21.9;memory CD4 T-cell: 14.6;memory CD8 T-cell: 21.1;naive CD4 T-cell: 18.8;naive CD8 T-cell: 12.3;T-reg: 27.8" "Lineage enriched" "Detected in single" 158 "T-cells: 27.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.07e-2)" "unprognostic (1.03e-3)" "unprognostic (1.89e-3)" "unprognostic (1.39e-3)" "unprognostic (2.09e-4)" "unprognostic (1.08e-2)" "unprognostic (6.75e-2)" "unprognostic (5.47e-3)" "unprognostic (7.77e-2)" "unprognostic (4.14e-2)" "unprognostic (3.86e-1)" "unprognostic (2.52e-3)" "unprognostic (2.38e-1)" "unprognostic (8.34e-2)" "unprognostic (3.23e-1)" "unprognostic (2.55e-2)" 0.1 0.1 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 3.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.4 0.1 0.0 46.9 0.1 0.0 3.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 21.9 0.0 14.6 21.1 0.0 0.0 18.8 12.3 0.1 0.0 0.0 0.0 27.8 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 TRBV16 "TCRBV16S1, TCRBV25S1A2PT" ENSG00000275243 "T cell receptor beta variable 16" A0A087WV62 7 142598016-142598469 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enhanced" "Detected in single" "Early spermatids: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 2.6;memory CD8 T-cell: 4.3;naive CD4 T-cell: 2.3;T-reg: 5.8" "Lineage enriched" "Detected in single" 59 "T-cells: 5.8" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (9.44e-3)" 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 1.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.3 0.0 0.0 2.3 0.8 0.0 0.0 0.0 0.0 5.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 TRBV17 "TCRBV17S1, TCRBV26S1P" ENSG00000277880 "T cell receptor beta variable 17 (non-functional)" 7 142601628-142602360 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRBV18 TCRBV18S1 ENSG00000276557 "T cell receptor beta variable 18" A0A087X0M5 7 142615716-142616415 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 17 "lymphoid tissue: 27.5" "Cell type enriched" "Detected in single" 13 "T-cells: 6.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 102.0" "Lineage enriched" "Detected in single" 316 "T-cells: 102.0" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.55e-2)" "unprognostic (1.14e-3)" "unprognostic (4.53e-3)" "unprognostic (7.74e-4)" "unprognostic (2.60e-2)" "unprognostic (1.08e-4)" "unprognostic (3.11e-1)" "unprognostic (6.76e-3)" "unprognostic (3.67e-2)" "unprognostic (7.81e-4)" "unprognostic (1.41e-1)" "unprognostic (1.72e-1)" "unprognostic (3.28e-6)" "unprognostic (3.80e-1)" "unprognostic (4.42e-2)" "unprognostic (4.02e-2)" "unprognostic (2.47e-2)" 0.2 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.1 0.1 0.8 8.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.0 0.1 0.0 0.0 0.3 1.6 0.2 0.0 1.7 0.5 0.0 0.0 27.5 0.2 0.0 2.2 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 3.0 0.2 46.6 10.8 0.0 0.0 49.3 16.9 0.2 0.1 0.1 0.0 102.0 14.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 TRBV19 "TCRBV17S1A1T, TCRBV19S1" ENSG00000211746 "T cell receptor beta variable 19" A0A075B6N1 7 142618849-142619532 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 53.4" "Cell type enriched" "Detected in some" 5 "T-cells: 11.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 50.8;memory CD8 T-cell: 40.2;naive CD4 T-cell: 71.1;naive CD8 T-cell: 53.5;T-reg: 88.5" "Lineage enriched" "Detected in single" 191 "T-cells: 88.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.62e-3)" "unprognostic (8.91e-4)" "unprognostic (1.14e-2)" "unprognostic (5.81e-3)" "unprognostic (2.38e-2)" "unprognostic (2.29e-4)" "unprognostic (3.96e-3)" "unprognostic (3.62e-3)" "unprognostic (4.51e-3)" "unprognostic (1.14e-2)" "unprognostic (2.07e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (9.78e-2)" "unprognostic (4.14e-2)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" 0.6 0.1 0.0 5.7 0.0 0.7 0.7 0.1 0.3 0.8 0.0 1.2 0.5 0.5 0.0 0.4 0.3 3.7 0.1 0.1 0.0 0.2 0.7 1.1 28.5 0.1 0.0 0.4 0.1 0.3 0.1 0.0 0.1 0.4 2.1 0.0 0.2 0.3 0.1 0.4 3.0 0.2 0.0 3.8 2.9 0.1 0.1 53.4 0.5 0.2 1.9 0.5 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 1.4 0.1 13.5 0.4 50.8 40.2 0.1 0.0 71.1 53.5 0.4 0.1 0.2 0.0 88.5 15.5 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 TRBV2 "TCRBV22S1A2N1T, TCRBV2S1" ENSG00000226660 "T cell receptor beta variable 2" A0A1B0GX68 7 142300924-142301432 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "lymphoid tissue: 89.2" "Cell type enriched" "Detected in single" 80 "T-cells: 8.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 120.3;memory CD8 T-cell: 64.5;naive CD4 T-cell: 71.5;naive CD8 T-cell: 44.5;T-reg: 122.7" "Lineage enriched" "Detected in many" 21 "T-cells: 122.7" "Cell line enriched" "Detected in single" 10 "RPMI-8226: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.62e-4)" "unprognostic (4.94e-4)" "unprognostic (5.79e-2)" "unprognostic (1.29e-3)" "unprognostic (1.09e-1)" "unprognostic (4.71e-5)" "unprognostic (3.60e-2)" "unprognostic (3.74e-2)" "unprognostic (9.43e-2)" "unprognostic (1.16e-2)" "unprognostic (1.94e-2)" "unprognostic (1.77e-1)" "unprognostic (3.70e-5)" "unprognostic (3.83e-1)" "unprognostic (6.31e-2)" "unprognostic (1.89e-1)" "unprognostic (3.41e-2)" 1.1 0.3 0.0 8.3 0.0 3.9 1.2 0.0 0.1 1.1 0.0 2.6 2.5 0.3 1.1 1.7 0.2 2.4 0.1 0.0 0.0 0.4 0.9 1.6 25.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.8 2.1 0.0 0.3 0.5 0.0 0.3 1.7 0.8 0.0 6.8 3.5 0.3 0.0 89.2 0.5 0.3 22.1 3.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.9 0.0 5.5 0.1 120.3 64.5 0.3 0.1 71.5 44.5 1.2 0.1 0.1 5.8 122.7 29.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 TRBV20-1 "TCRBV20S1, TCRBV2S1, TRBV201" ENSG00000211747 "T cell receptor beta variable 20-1" A0A075B6N2 7 142626649-142627399 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 161.4" "Cell type enriched" "Detected in some" 15 "T-cells: 26.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 351.7" "Lineage enriched" "Detected in many" 115 "T-cells: 351.7" "Group enriched" "Detected in some" 8 "Karpas-707: 2.4;MOLT-4: 5.0;REH: 2.5;RH-30: 3.0" "Not detected" "Not detected" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.25e-3)" "prognostic favorable (4.40e-5)" "unprognostic (1.39e-2)" "prognostic favorable (8.49e-4)" "unprognostic (8.83e-2)" "unprognostic (2.69e-3)" "unprognostic (4.34e-2)" "unprognostic (8.75e-3)" "prognostic favorable (1.37e-4)" "unprognostic (1.30e-2)" "unprognostic (8.86e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (1.11e-5)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (1.05e-1)" "unprognostic (3.41e-2)" 1.7 0.2 0.1 13.6 0.1 5.1 0.6 0.1 0.2 0.6 0.0 2.4 0.5 0.3 0.0 0.7 0.7 3.2 0.2 0.1 0.0 0.5 0.6 2.7 53.3 0.2 0.0 0.5 0.2 0.0 0.8 0.0 0.3 0.9 3.1 0.0 0.5 0.2 0.1 1.9 6.0 0.9 0.1 7.3 3.6 0.3 0.1 161.4 1.0 0.0 6.0 2.2 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 5.0 0.2 0.0 0.0 0.0 2.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.6 0.2 4.6 0.3 231.9 1.1 192.7 76.4 0.6 0.6 144.0 58.9 2.3 0.3 0.8 0.4 351.7 50.2 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 TRBV20OR9-2 "TCRBV20S2, TCRBV2O, TCRBV2S2O, TRBV20/OR9-2" ENSG00000205274 "T cell receptor beta variable 20/OR9-2 (non-functional)" 9 33617762-33618506 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 11.4;pituitary gland: 2.8;placenta: 2.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.0" "Region enhanced" "Detected in many" "pons: 11.4" "Immune cell enhanced" "Detected in many" "T-reg: 17.0" "Lineage enriched" "Detected in single" 31 "T-cells: 17.0" "Cell line enhanced" "Detected in some" "BEWO: 1.2;HEL: 1.4;MOLT-4: 1.0;RH-30: 5.0;SuSa: 1.1" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.53e-1)" "unprognostic (3.70e-2)" "unprognostic (3.01e-2)" "unprognostic (1.31e-1)" "unprognostic (1.51e-1)" 0.0 0.0 0.4 0.1 0.7 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 6.7 6.3 0.0 0.8 0.0 2.8 2.1 11.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 1.0 0.3 0.3 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 5.7 0.0 6.9 4.0 0.0 0.0 6.4 5.3 0.0 0.0 0.0 0.0 17.0 1.9 0.4 0.7 1.2 1.1 0.3 0.7 6.7 6.3 11.4 1.2 2.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRBV23-1 "TCRBV19S1P, TCRBV23S1, TRBV231" ENSG00000211749 "T cell receptor beta variable 23-1 (non-functional)" 7 142645961-142646467 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 11.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.02e-5)" "unprognostic (7.32e-4)" "unprognostic (1.71e-4)" "unprognostic (1.34e-3)" "unprognostic (6.71e-3)" "unprognostic (1.28e-3)" "unprognostic (4.64e-2)" "unprognostic (1.17e-6)" "unprognostic (1.14e-1)" "unprognostic (5.86e-3)" "unprognostic (1.37e-1)" 0.3 0.0 0.0 3.4 0.1 2.2 0.1 0.1 0.1 0.2 0.0 0.4 0.3 0.1 0.6 0.1 0.2 1.0 0.3 0.0 0.0 0.2 0.2 0.7 8.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.4 0.0 0.2 0.1 2.0 0.1 0.0 2.2 0.2 0.0 0.0 11.7 0.3 0.1 5.9 0.9 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.9 0.5 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.1 1.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 TRBV24-1 "TCRBV15S1, TCRBV24S1, TRBV241" ENSG00000211750 "T cell receptor beta variable 24-1" A0A075B6N3 7 142656701-142657213 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.7;lymphoid tissue: 6.7" "Cell type enriched" "Detected in single" 23 "T-cells: 2.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "basal ganglia: 2.7" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 26.6" "Lineage enriched" "Detected in single" 129 "T-cells: 26.6" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.42e-2)" "unprognostic (1.64e-5)" "unprognostic (1.59e-1)" "unprognostic (9.71e-3)" "unprognostic (3.82e-1)" "unprognostic (9.30e-2)" "unprognostic (3.08e-2)" "unprognostic (1.81e-1)" "unprognostic (6.73e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-7)" "unprognostic (2.36e-1)" "unprognostic (5.80e-2)" "unprognostic (7.76e-3)" "unprognostic (4.39e-2)" 0.2 0.0 0.1 0.0 2.7 0.2 0.0 0.0 0.5 0.3 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.4 2.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 1.0 0.0 0.9 0.2 0.0 1.3 1.6 0.4 0.5 6.7 0.1 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 9.0 0.0 5.7 0.0 15.4 15.5 0.0 0.0 11.4 26.6 0.2 0.0 0.0 0.0 23.2 4.6 0.1 2.7 0.0 0.5 0.2 0.1 0.1 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 TRBV25-1 "TCRBV11S1A1T, TCRBV25S1, TRBV251" ENSG00000282499 "T cell receptor beta variable 25-1" A0A075B6N4 7 142670740-142671244 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 24.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.5;T-cells: 2.7" "Group enriched" "Detected in some" 9 "basal ganglia: 4.4;cerebral cortex: 2.3" "Group enriched" "Detected in many" 51 "MAIT T-cell: 8.3;memory CD4 T-cell: 8.7;memory CD8 T-cell: 13.3;naive CD4 T-cell: 12.4;naive CD8 T-cell: 12.1;T-reg: 25.8" "Lineage enriched" "Detected in single" 106 "T-cells: 25.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.1 0.8 0.2 1.7 4.4 0.5 0.0 0.0 2.3 0.0 0.0 0.1 0.4 0.1 0.0 0.5 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.3 3.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 3.0 0.0 0.8 0.1 0.0 1.0 0.2 0.7 0.2 24.8 0.1 0.9 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.3 0.0 8.7 13.3 0.2 0.0 12.4 12.1 0.2 0.0 0.0 0.0 25.8 2.9 0.2 4.4 0.0 2.3 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 TRBV27 "TCRBV14S1, TCRBV27S1" ENSG00000211752 "T cell receptor beta variable 27" A0A0K0K1C4 7 142715346-142715861 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 81.6" "Cell type enriched" "Detected in some" 4 "T-cells: 6.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 61.1;memory CD8 T-cell: 112.2;naive CD4 T-cell: 48.2;naive CD8 T-cell: 75.8;T-reg: 94.7" "Lineage enriched" "Detected in single" 137 "T-cells: 112.2" "Group enriched" "Detected in some" 4 "HAP1: 2.9;JURKAT: 3.3;U-937: 3.6" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.08e-2)" "unprognostic (2.10e-2)" "unprognostic (5.66e-2)" "unprognostic (5.85e-4)" "unprognostic (8.84e-2)" "unprognostic (7.89e-2)" "unprognostic (1.91e-2)" "unprognostic (1.28e-4)" "unprognostic (1.49e-1)" "unprognostic (4.36e-2)" "unprognostic (1.91e-7)" "unprognostic (4.03e-1)" "unprognostic (3.91e-2)" "unprognostic (8.10e-2)" "unprognostic (6.43e-2)" 0.6 0.5 0.0 3.5 0.6 1.9 0.8 0.0 0.3 0.7 0.0 1.2 1.0 0.9 0.1 0.8 0.2 1.8 0.2 0.0 0.0 0.4 0.5 1.7 19.7 0.0 0.3 0.5 0.2 0.0 0.1 0.1 0.0 0.5 1.7 0.0 1.7 0.0 0.3 0.2 2.8 0.2 0.0 4.8 1.9 5.7 0.2 81.6 0.6 0.8 10.6 1.6 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.4 0.1 0.6 3.3 0.0 10.4 0.1 61.1 112.2 0.1 0.1 48.2 75.8 0.8 0.1 0.2 0.1 94.7 27.3 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 TRBV28 "TCRBV28S1, TCRBV3S1" ENSG00000211753 "T cell receptor beta variable 28" A0A5B6 7 142720660-142721160 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "lymphoid tissue: 199.4" "Cell type enriched" "Detected in some" 12 "T-cells: 33.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 154.5" "Lineage enriched" "Detected in many" 79 "T-cells: 154.5" "Cell line enriched" "Detected in single" 30 "JURKAT: 23.7" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.34e-3)" "prognostic favorable (1.52e-4)" "unprognostic (1.94e-3)" "prognostic favorable (2.48e-5)" "unprognostic (5.54e-2)" "prognostic favorable (3.62e-4)" "unprognostic (5.76e-2)" "unprognostic (2.33e-3)" "prognostic favorable (1.35e-5)" "unprognostic (2.47e-3)" "unprognostic (3.33e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.48e-8)" "unprognostic (1.27e-1)" "unprognostic (9.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.94e-3)" 0.5 0.9 0.0 9.3 0.2 3.0 2.1 0.2 0.2 1.2 0.0 2.6 3.4 0.6 0.3 1.3 0.3 2.9 0.5 0.0 0.0 0.5 1.9 3.5 24.8 0.0 0.0 0.5 0.2 0.0 0.1 0.1 0.0 0.7 1.7 0.0 1.3 0.3 0.2 0.1 4.0 0.3 0.0 9.5 2.0 0.4 0.0 199.4 0.5 0.6 33.8 5.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 3.8 0.0 26.1 0.5 94.5 80.1 0.1 0.2 98.1 53.3 1.9 1.6 0.1 0.4 154.5 34.1 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 0.0 0.6 0.0 TRBV29-1 "TCRBV29S1, TCRBV4S1A1T, TRBV291" ENSG00000232869 "T cell receptor beta variable 29-1" A0A5B7 7 142740206-142740894 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 98.5" "Cell type enriched" "Detected in single" 11 "T-cells: 4.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "MAIT T-cell: 45.1;memory CD4 T-cell: 128.6;memory CD8 T-cell: 83.2;naive CD4 T-cell: 137.8;naive CD8 T-cell: 110.8;T-reg: 178.2" "Lineage enriched" "Detected in many" 69 "T-cells: 178.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "prognostic favorable (1.23e-4)" "unprognostic (9.31e-4)" "unprognostic (1.29e-1)" "unprognostic (8.13e-3)" "unprognostic (3.28e-2)" "unprognostic (3.47e-4)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (9.15e-2)" "unprognostic (3.93e-2)" "unprognostic (1.94e-1)" "unprognostic (2.03e-1)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.45e-1)" "unprognostic (2.46e-2)" "unprognostic (2.29e-1)" "unprognostic (2.05e-1)" 0.8 0.3 0.0 6.5 0.0 4.4 1.2 0.3 0.1 1.4 0.1 1.9 2.7 0.6 0.0 1.0 0.3 2.6 0.2 0.0 0.0 0.4 1.2 1.5 21.7 0.0 0.0 0.6 21.2 0.0 0.1 0.0 0.0 0.7 2.0 0.0 0.7 0.6 0.1 0.4 3.9 1.2 0.0 5.4 2.3 0.1 0.0 98.5 0.6 0.5 23.4 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.1 0.7 0.1 45.1 2.0 128.6 83.2 0.1 1.8 137.8 110.8 2.5 0.2 0.3 0.7 178.2 51.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 TRBV3-1 "TCRBV3S1, TCRBV9S1A1T, TRBV31" ENSG00000237702 "T cell receptor beta variable 3-1" A0A576 7 142308542-142309048 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 22 "lymphoid tissue: 51.1" "Group enriched" "Detected in some" 22 "Plasma cells: 10.1;T-cells: 12.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 52.4;memory CD8 T-cell: 45.9;naive CD4 T-cell: 71.6;naive CD8 T-cell: 117.4;T-reg: 99.6" "Lineage enriched" "Detected in many" 32 "T-cells: 117.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.98e-5)" "unprognostic (2.38e-3)" "unprognostic (5.19e-3)" "unprognostic (2.46e-2)" "unprognostic (1.19e-2)" "unprognostic (6.19e-4)" "unprognostic (1.46e-2)" "unprognostic (5.42e-2)" "unprognostic (4.10e-3)" "unprognostic (1.85e-2)" "unprognostic (1.56e-1)" "unprognostic (2.20e-1)" "unprognostic (2.01e-4)" "unprognostic (1.75e-1)" "unprognostic (1.13e-3)" "unprognostic (1.53e-2)" "unprognostic (1.26e-2)" 0.4 0.0 0.0 5.3 0.0 1.9 0.4 0.0 0.1 0.3 0.0 0.9 0.5 0.3 0.1 0.3 0.3 1.2 0.2 0.0 0.0 0.1 0.2 0.8 10.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.3 1.0 0.0 0.8 0.2 0.0 0.2 2.2 0.2 0.0 2.7 1.0 0.0 0.0 51.1 0.3 0.1 10.4 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.6 0.1 0.3 1.8 0.1 16.6 0.2 52.4 45.9 0.1 0.1 71.6 117.4 2.0 0.4 0.1 0.4 99.6 29.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 TRBV30 "TCRBV20S1A1N2, TCRBV30S1" ENSG00000237254 "T cell receptor beta variable 30" A0A0K0K1B3 7 142812586-142813399 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 25.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 1.9;Gastric mucus-secreting cells: 1.1;T-cells: 6.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 162.3" "Lineage enriched" "Detected in many" 49 "T-cells: 162.3" "Cell line enriched" "Detected in some" 6 "MOLT-4: 41.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (5.72e-3)" "unprognostic (2.36e-3)" "unprognostic (1.74e-2)" "unprognostic (2.41e-2)" "unprognostic (3.56e-4)" "unprognostic (7.71e-2)" "unprognostic (4.19e-2)" "unprognostic (2.60e-3)" "unprognostic (2.32e-3)" "unprognostic (4.96e-2)" "unprognostic (4.95e-2)" "unprognostic (4.37e-4)" "unprognostic (3.50e-1)" "unprognostic (1.33e-1)" "unprognostic (1.22e-1)" "prognostic favorable (2.88e-4)" 0.2 0.0 0.2 1.1 0.4 2.2 0.1 0.0 0.2 0.4 0.0 0.6 2.1 0.0 0.1 0.9 0.1 1.7 0.0 0.1 0.0 0.0 0.3 1.3 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 2.5 0.2 0.0 1.1 1.2 0.1 0.0 2.6 0.9 0.0 0.1 25.4 0.1 0.0 13.3 1.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.0 0.0 41.3 0.0 0.0 6.7 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 2.1 0.1 30.7 3.3 74.2 42.3 0.2 0.9 89.9 49.6 0.2 0.1 0.0 0.5 162.3 21.6 0.2 0.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.1 TRBV4-1 "BV07S1J2.7, TCRBV4S1, TCRBV7S1A1N2T, TRBV41" ENSG00000211710 "T cell receptor beta variable 4-1" A0A577 7 142313184-142313666 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 115.0" "Cell type enriched" "Detected in some" 7 "T-cells: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 176.7" "Lineage enriched" "Detected in many" 89 "T-cells: 176.7" "Cell line enriched" "Detected in single" 8 "U-266/84: 1.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.58e-4)" "unprognostic (3.14e-3)" "unprognostic (1.49e-2)" "unprognostic (5.74e-4)" "unprognostic (1.88e-1)" "unprognostic (6.43e-3)" "unprognostic (5.89e-2)" "unprognostic (2.96e-2)" "unprognostic (6.43e-3)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (2.79e-2)" "unprognostic (6.71e-5)" "unprognostic (1.76e-1)" "unprognostic (3.56e-2)" "unprognostic (1.67e-2)" "unprognostic (8.99e-2)" 0.5 0.0 0.0 7.1 0.1 2.6 0.7 0.0 0.2 0.8 0.0 0.8 0.1 0.2 0.7 1.1 0.9 0.8 0.1 0.0 0.0 0.4 0.4 0.7 15.3 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.5 0.8 0.0 0.2 0.0 0.1 0.2 4.3 0.4 0.1 4.1 2.3 0.1 0.0 115.0 0.3 0.0 10.0 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.0 0.2 0.1 2.5 0.1 40.2 0.1 69.8 167.3 0.0 0.2 152.1 152.7 1.9 0.8 0.4 0.8 176.7 43.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 TRBV4-2 "TCRBV4S2, TCRBV7S3A2T, TRBV42" ENSG00000211745 "T cell receptor beta variable 4-2" A0A539 7 142345421-142345985 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 21.0" "Cell type enriched" "Detected in some" 8 "T-cells: 23.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 100.2" "Lineage enriched" "Detected in single" 293 "T-cells: 100.2" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.89e-3)" "unprognostic (4.65e-4)" "unprognostic (1.28e-3)" "unprognostic (1.06e-2)" "unprognostic (4.60e-2)" "unprognostic (7.05e-4)" "unprognostic (2.11e-1)" "unprognostic (1.67e-2)" "unprognostic (1.19e-3)" "unprognostic (1.32e-2)" "unprognostic (6.75e-2)" "unprognostic (3.42e-1)" "unprognostic (2.82e-4)" "unprognostic (5.50e-2)" "unprognostic (5.99e-2)" "unprognostic (2.16e-1)" "unprognostic (1.48e-2)" 0.2 0.0 0.0 1.4 0.0 0.6 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.3 0.2 0.4 5.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 1.5 0.1 0.0 2.3 0.3 0.5 0.0 21.0 0.3 0.0 4.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 100.2 0.0 25.6 27.8 0.1 0.0 23.9 14.4 0.1 0.0 0.2 0.3 44.8 8.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 23.9 0.0 0.0 0.0 TRBV5-1 "TCRBV5S1, TCRBV5S1A1T, TRBV51" ENSG00000211734 "T cell receptor beta variable 5-1" A0A578 7 142320677-142321544 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 44.0" "Cell type enriched" "Detected in some" 11 "T-cells: 13.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 211.6;T-reg: 295.5" "Lineage enriched" "Detected in many" 111 "T-cells: 295.5" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.26e-4)" "unprognostic (1.36e-3)" "unprognostic (2.59e-2)" "unprognostic (1.49e-3)" "unprognostic (6.65e-2)" "unprognostic (7.02e-5)" "unprognostic (2.55e-2)" "unprognostic (3.66e-2)" "unprognostic (4.29e-3)" "unprognostic (5.85e-4)" "unprognostic (3.55e-2)" "unprognostic (4.36e-1)" "unprognostic (5.96e-7)" "unprognostic (2.63e-1)" "unprognostic (2.52e-2)" "unprognostic (4.06e-2)" "unprognostic (2.97e-2)" 0.3 0.0 0.0 4.8 0.0 1.1 0.2 0.0 0.0 0.4 0.0 0.7 1.0 0.1 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.1 0.2 0.7 9.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.2 0.0 0.0 0.3 1.9 0.1 0.0 2.6 1.6 0.2 0.0 44.0 0.2 0.0 8.9 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 2.6 0.2 11.0 0.4 166.1 65.4 0.4 0.4 211.6 128.7 2.6 0.5 0.5 0.3 295.5 82.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 TRBV5-3 "TCRBV5S3, TCRBV5S5P, TRBV53" ENSG00000211715 "T cell receptor beta variable 5-3 (non-functional)" 7 142389202-142389668 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 27 "MAIT T-cell: 2.7" "Lineage enriched" "Detected in single" 27 "T-cells: 2.7" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: T-cells - T-cell receptor" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRBV5-4 "TCRBV5S4, TCRBV5S6A3N2T, TRBV54" ENSG00000230099 "T cell receptor beta variable 5-4" A0A0C4DH59 7 142462916-142463581 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "lymphoid tissue: 22.1;pancreas: 11.6" "Group enriched" "Detected in some" 9 "Plasma cells: 6.1;T-cells: 6.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 115.7" "Lineage enriched" "Detected in many" 115 "T-cells: 115.7" "Cell line enriched" "Detected in some" 5 "MOLT-4: 11.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.48e-3)" "unprognostic (6.75e-4)" "unprognostic (1.60e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-1)" "unprognostic (1.76e-3)" "unprognostic (5.82e-2)" "unprognostic (2.79e-2)" "unprognostic (1.59e-2)" "unprognostic (4.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.60e-4)" "unprognostic (2.77e-1)" "unprognostic (4.95e-2)" "unprognostic (4.78e-3)" "unprognostic (1.64e-2)" 0.2 0.1 0.0 2.4 0.2 1.2 0.1 0.0 0.0 0.2 0.0 0.7 0.8 0.0 0.1 0.3 0.1 0.5 0.3 0.0 0.0 0.1 0.2 0.4 8.2 0.2 0.0 0.0 11.6 0.0 0.0 0.0 0.2 0.2 1.0 0.7 0.5 0.0 0.2 0.3 1.1 0.0 0.0 2.2 1.0 0.2 0.0 22.1 0.2 0.0 8.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 2.3 0.0 0.0 0.5 0.0 0.2 0.2 0.0 1.3 0.1 2.1 0.0 49.7 26.7 0.0 0.1 62.8 36.4 1.0 0.1 0.1 0.1 115.7 18.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 TRBV5-5 "TCRBV5S3A2T, TCRBV5S5, TRBV55" ENSG00000211725 "T cell receptor beta variable 5-5" A0A597 7 142482548-142483019 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 23 "lymphoid tissue: 18.6" "Cell type enriched" "Detected in single" 23 "T-cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "memory CD4 T-cell: 36.7;memory CD8 T-cell: 28.0;naive CD4 T-cell: 38.6;naive CD8 T-cell: 29.0;T-reg: 41.9" "Lineage enriched" "Detected in many" 30 "T-cells: 41.9" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (4.96e-5)" "unprognostic (4.74e-3)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "unprognostic (2.19e-1)" "unprognostic (1.98e-4)" "unprognostic (2.84e-3)" "unprognostic (9.58e-2)" "unprognostic (7.35e-2)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (4.27e-4)" "unprognostic (7.42e-2)" "unprognostic (8.32e-3)" "unprognostic (9.06e-2)" 0.1 0.0 0.2 1.8 0.1 0.7 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.1 2.2 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.5 0.0 0.8 18.6 0.1 0.0 4.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.6 0.0 0.8 0.0 36.7 28.0 0.1 0.1 38.6 29.0 0.8 0.0 0.1 0.0 41.9 11.3 0.2 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.2 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 TRBV5-6 "TCRBV5S2, TCRBV5S6, TRBV56" ENSG00000211728 "T cell receptor beta variable 5-6" A0A599 7 142500028-142500534 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "lymphoid tissue: 33.8" "Group enriched" "Detected in some" 21 "Early spermatids: 13.5;Late spermatids: 14.6;T-cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 40.2;memory CD8 T-cell: 22.9;naive CD4 T-cell: 35.9;naive CD8 T-cell: 45.2;T-reg: 66.0" "Lineage enriched" "Detected in many" 56 "T-cells: 66.0" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.27e-3)" "unprognostic (8.46e-3)" "unprognostic (1.20e-1)" "unprognostic (7.21e-2)" "unprognostic (5.25e-1)" "unprognostic (3.45e-4)" "unprognostic (5.72e-2)" "unprognostic (6.24e-2)" "unprognostic (1.57e-2)" "unprognostic (1.46e-3)" "unprognostic (2.64e-2)" "unprognostic (2.39e-1)" "unprognostic (2.26e-7)" "unprognostic (7.62e-2)" "unprognostic (3.14e-2)" "unprognostic (2.41e-1)" "unprognostic (1.34e-1)" 0.2 0.0 0.0 2.1 0.0 0.7 0.3 0.0 0.1 0.5 0.0 0.6 0.3 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.1 0.1 0.8 7.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.3 0.0 0.2 1.1 0.1 0.0 1.9 0.4 1.7 0.0 33.8 0.1 0.1 5.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.9 0.0 3.0 0.1 40.2 22.9 0.1 0.1 35.9 45.2 1.1 0.0 0.1 0.2 66.0 17.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 TRBV5-7 "TCRBV5S7, TCRBV5S7P, TRBV57" ENSG00000211731 "T cell receptor beta variable 5-7 (non-functional)" 7 142520090-142520556 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.1;T-reg: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "unprognostic (1.10e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 0.0 0.0 1.1 0.8 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRBV6-1 "TCRBV13S3, TCRBV6S1, TRBV61" ENSG00000211706 "T cell receptor beta variable 6-1" A0A0K0K1D8 7 142328297-142328786 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 48 "lymphoid tissue: 89.2" "Cell type enriched" "Detected in single" 10 "T-cells: 5.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 118.0;T-reg: 74.1" "Lineage enriched" "Detected in single" 126 "T-cells: 118.0" "Cell line enriched" "Detected in single" 11 "SCLC-21H: 1.5" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.12e-2)" "unprognostic (3.42e-4)" "unprognostic (3.40e-3)" "unprognostic (1.20e-2)" "unprognostic (1.22e-1)" "unprognostic (4.75e-5)" "unprognostic (1.08e-3)" "unprognostic (2.00e-1)" "unprognostic (2.18e-2)" "unprognostic (1.86e-5)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (1.85e-4)" "unprognostic (2.41e-1)" "unprognostic (2.48e-2)" "unprognostic (3.51e-2)" "unprognostic (3.56e-2)" 0.2 0.1 0.0 4.8 0.0 0.9 0.4 0.0 0.0 0.4 0.0 0.9 0.7 0.1 0.1 0.2 0.2 1.7 0.2 0.0 0.0 0.1 0.3 0.8 8.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.4 0.0 0.0 0.3 1.8 0.2 0.0 2.2 0.9 0.0 0.0 89.2 0.4 0.1 10.2 1.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 118.0 0.0 37.7 33.2 0.1 0.1 39.0 18.5 0.9 0.0 0.1 0.1 74.1 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 TRBV6-2 "TCRBV13S2A1T, TCRBV6S2, TRBV62" ENSG00000283063 "T cell receptor beta variable 6-2" "A0A0J9YXY3, P0DPF7" 7 142349152-142349664 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 8.2" "Cell type enriched" "Detected in single" 10 "T-cells: 6.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 92.1" "Lineage enriched" "Detected in single" 175 "T-cells: 92.1" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.2 0.0 0.0 2.4 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.5 8.2 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 1.5 0.1 0.0 2.3 0.2 0.0 0.0 4.6 0.3 0.0 5.8 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 92.1 0.2 24.0 26.4 0.0 0.0 21.7 17.5 0.5 0.0 0.1 0.1 40.3 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 TRBV6-4 "TCRBV13S5, TCRBV6S4, TRBV64" ENSG00000211713 "T cell receptor beta variable 6-4" A0A1B0GX49 7 142380806-142381261 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.2" "Cell type enriched" "Detected in single" 6 "T-cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 13 "MAIT T-cell: 231.6" "Lineage enriched" "Detected in single" 1381 "T-cells: 231.6" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.60e-3)" "unprognostic (4.64e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-2)" "unprognostic (4.79e-1)" "unprognostic (2.98e-1)" "unprognostic (1.54e-1)" "unprognostic (9.07e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.7 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 231.6 0.0 2.4 17.3 0.0 0.0 4.1 3.0 0.0 0.0 0.0 0.0 4.4 2.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 TRBV6-5 "TCRBV13S1, TCRBV6S5, TRBV65" ENSG00000211721 "T cell receptor beta variable 6-5" A0A0K0K1A5 7 142450947-142451448 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 82.3" "Cell type enriched" "Detected in single" 121 "T-cells: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 133.8;T-reg: 137.9" "Lineage enriched" "Detected in many" 54 "T-cells: 137.9" "Cell line enriched" "Detected in some" 8 "HL-60: 61.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.42e-3)" "unprognostic (7.43e-4)" "unprognostic (1.11e-2)" "unprognostic (2.20e-3)" "unprognostic (1.38e-1)" "unprognostic (8.63e-5)" "unprognostic (1.55e-2)" "unprognostic (1.51e-3)" "unprognostic (8.72e-3)" "unprognostic (2.11e-3)" "unprognostic (7.03e-2)" "unprognostic (4.82e-1)" "prognostic unfavorable (5.40e-5)" "unprognostic (3.12e-2)" "unprognostic (4.17e-2)" "unprognostic (7.43e-3)" "unprognostic (3.06e-2)" 0.4 0.2 0.0 4.1 0.0 2.3 0.5 0.0 0.1 0.4 0.0 0.9 1.0 0.2 0.0 0.2 0.3 1.6 0.1 0.0 0.0 0.1 0.3 2.4 16.1 0.0 0.0 0.3 7.3 0.0 0.0 0.1 0.0 0.3 1.2 0.2 0.4 0.1 0.0 0.3 2.0 0.3 0.0 3.4 1.6 0.1 0.0 82.3 0.4 0.7 12.0 1.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 61.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.5 0.2 0.2 1.0 0.1 32.8 0.3 78.7 76.2 0.1 0.4 92.0 133.8 2.5 0.2 0.4 0.4 137.9 59.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.1 TRBV6-6 "TCRBV13S6A2T, TCRBV6S6, TRBV66" ENSG00000211724 "T cell receptor beta variable 6-6" A0A0A6YYG2 7 142469537-142470013 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 14.7" "Cell type enriched" "Detected in single" 37 "T-cells: 3.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 81.4" "Lineage enriched" "Detected in single" 98 "T-cells: 81.4" "Cell line enriched" "Detected in some" 10 "HL-60: 10.4" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.69e-4)" "unprognostic (3.82e-4)" "unprognostic (3.66e-2)" "unprognostic (2.55e-2)" "unprognostic (8.55e-2)" "unprognostic (9.93e-5)" "unprognostic (4.36e-1)" "unprognostic (1.94e-2)" "unprognostic (1.09e-2)" "unprognostic (3.42e-2)" "unprognostic (5.90e-2)" "unprognostic (2.27e-1)" "unprognostic (1.78e-3)" "unprognostic (2.40e-1)" "unprognostic (2.22e-2)" "unprognostic (4.18e-2)" "unprognostic (2.01e-2)" 0.2 0.0 0.0 2.7 0.1 0.8 0.5 0.0 0.1 0.1 0.0 0.8 0.8 0.1 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.2 0.0 0.9 5.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.7 0.1 1.6 0.0 0.0 0.1 1.2 0.1 0.0 2.9 0.8 0.0 0.0 14.7 0.2 0.0 10.6 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.5 0.3 14.7 0.0 34.6 47.9 0.0 0.1 48.9 21.3 0.8 0.1 0.2 0.2 81.4 12.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 TRBV6-7 "TCRBV13S8P, TCRBV6S7, TRBV67" ENSG00000253188 "T cell receptor beta variable 6-7 (non-functional)" 7 142487863-142488295 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 1.6;lymphoid tissue: 1.3;pancreas: 1.6;testis: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.9" "Lineage enriched" "Detected in single" 6 "T-cells: 1.9" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.38e-1)" 0.0 0.0 0.7 0.0 0.5 0.2 0.0 0.5 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.0 0.0 0.0 0.3 0.7 0.5 0.0 1.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.3 1.6 1.3 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.7 0.0 0.0 1.9 0.3 0.3 0.0 0.0 0.0 0.7 0.1 0.7 0.5 0.5 0.9 1.1 0.5 0.7 0.5 0.7 0.4 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRBV6-8 "TCRBV13S7P, TCRBV6S8, TRBV68" ENSG00000253534 "T cell receptor beta variable 6-8" A0A0A6YYG3 7 142507382-142507810 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "Early spermatids: 1.1;Late spermatids: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 12 "T-cells: 1.1" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (2.52e-1)" 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRBV7-1 "TCRBV6S7P, TCRBV7S1, TRBV71" ENSG00000211707 "T cell receptor beta variable 7-1 (non-functional)" 7 142332182-142332701 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 8.1" "Group enriched" "Detected in some" 280 "Early spermatids: 75.2;Late spermatids: 36.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 2.0;naive CD4 T-cell: 1.8;T-reg: 2.8" "Lineage enriched" "Detected in single" 29 "T-cells: 2.8" "Cell line enriched" "Detected in single" 5 "SCLC-21H: 1.8" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (1.38e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 0.6 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 2.8 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRBV7-2 "TCRBV6S5A1N1, TCRBV7S2, TRBV72" ENSG00000282939 "T cell receptor beta variable 7-2" A0A1B0GXF2 7 142352819-142353358 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "epididymis: 35.6;lymphoid tissue: 85.5" "Cell type enriched" "Detected in some" 5 "T-cells: 33.0" "Region enriched" "Detected in single" 5 "hypothalamus: 1.1" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 397.4;T-reg: 570.3" "Lineage enriched" "Detected in many" 79 "T-cells: 570.3" "Group enriched" "Detected in some" 9 "JURKAT: 55.7;MOLT-4: 93.6;U-937: 49.0" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.9 0.1 0.0 15.0 0.1 0.0 2.2 0.0 0.2 2.2 0.0 1.2 1.7 0.0 35.6 0.6 0.5 0.0 0.2 0.0 1.1 0.5 0.3 5.5 49.0 0.0 0.0 0.1 0.2 0.0 1.0 0.1 0.0 0.3 4.6 0.0 0.4 0.4 0.0 0.2 4.7 1.1 0.0 5.8 4.7 0.0 0.2 85.5 0.7 0.0 43.0 2.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.7 0.0 0.0 0.0 0.0 93.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.4 0.3 0.0 0.0 49.0 0.0 1.1 2.3 0.7 11.9 1.2 55.5 0.7 397.4 178.6 2.7 0.7 302.2 110.6 1.2 0.5 1.9 7.2 570.3 104.9 0.0 0.1 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 0.0 0.0 0.0 0.2 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 TRBV7-3 "TCRBV6S1A1N1, TCRBV7S3, TRBV73" ENSG00000211714 "T cell receptor beta variable 7-3" 7 142384329-142384841 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9;testis: 2.7" "Group enriched" "Detected in some" 9 "Early spermatids: 32.5;Late spermatids: 39.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 31.9" "Lineage enriched" "Detected in single" 48 "T-cells: 31.9" "Cell line enhanced" "Detected in some" "ASC diff: 1.4;HBF TERT88: 2.3;HL-60: 1.6;RPTEC TERT1: 7.4;U-937: 3.8" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.78e-3)" "unprognostic (5.75e-4)" "unprognostic (1.76e-2)" "unprognostic (2.64e-3)" "unprognostic (3.07e-1)" "unprognostic (1.28e-4)" "unprognostic (4.17e-3)" "unprognostic (2.34e-2)" "unprognostic (2.06e-1)" "unprognostic (4.49e-3)" "unprognostic (8.36e-2)" "unprognostic (1.07e-1)" "unprognostic (5.57e-3)" "unprognostic (1.67e-1)" "unprognostic (1.21e-1)" "unprognostic (3.72e-1)" "unprognostic (3.10e-1)" 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.4 0.6 0.0 0.0 0.9 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.0 0.0 1.9 0.2 2.7 0.0 6.9 0.2 0.0 0.9 0.3 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.1 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.8 0.0 0.1 0.6 0.0 1.9 0.1 3.6 0.0 31.9 7.8 0.5 0.6 7.3 9.9 0.0 0.0 0.0 0.4 16.4 5.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.8 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 3.7 0.1 0.0 0.0 TRBV7-4 "TCRBV6S8A2T, TCRBV7S4, TRBV74" ENSG00000253409 "T cell receptor beta variable 7-4" A0A1B0GX95 7 142455174-142455635 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 17 "lymphoid tissue: 25.5;pancreas: 9.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 2.9" "Lineage enriched" "Detected in single" 29 "T-cells: 2.9" "Cell line enriched" "Detected in some" 7 "HL-60: 90.9" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (8.71e-5)" "unprognostic (4.23e-3)" "unprognostic (7.05e-5)" "unprognostic (8.94e-4)" "unprognostic (2.75e-1)" "unprognostic (3.50e-3)" "unprognostic (4.40e-1)" "unprognostic (1.95e-3)" "unprognostic (4.97e-3)" "unprognostic (3.73e-2)" "unprognostic (9.93e-3)" 0.0 0.0 0.0 0.6 0.1 1.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 3.5 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.1 0.0 0.0 25.5 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 90.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.7 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 1.0 0.6 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 2.9 0.5 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 TRBV7-6 "TCRBV6S3A1N1T, TCRBV7S6, TRBV76" ENSG00000211727 "T cell receptor beta variable 7-6" A0A1B0GX31 7 142492132-142492673 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 35.3" "Group enriched" "Detected in some" 15 "Gastric mucus-secreting cells: 5.1;T-cells: 7.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 22 "memory CD4 T-cell: 54.7;memory CD8 T-cell: 42.7;naive CD4 T-cell: 62.0;naive CD8 T-cell: 37.2;T-reg: 86.1" "Lineage enriched" "Detected in many" 52 "T-cells: 86.1" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (4.74e-2)" "unprognostic (1.21e-2)" "unprognostic (1.37e-2)" "unprognostic (4.25e-5)" "unprognostic (4.86e-3)" "unprognostic (4.06e-5)" "unprognostic (7.74e-2)" "unprognostic (3.83e-5)" "unprognostic (6.50e-2)" "unprognostic (1.33e-3)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (9.86e-5)" "unprognostic (1.83e-1)" "unprognostic (7.27e-2)" "unprognostic (5.90e-2)" "unprognostic (6.22e-3)" 0.1 0.0 0.5 3.7 0.3 1.3 0.2 0.2 0.4 0.1 0.1 0.6 0.0 0.1 5.3 1.7 0.1 1.4 0.0 0.5 0.2 0.1 0.4 0.8 6.9 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.6 0.0 0.4 0.3 0.0 0.3 1.1 0.0 0.4 3.7 1.1 0.5 1.0 35.3 0.2 0.0 7.6 2.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 2.5 0.1 54.7 42.7 0.1 0.3 62.0 37.2 1.6 0.1 0.1 0.1 86.1 17.1 0.5 0.3 0.2 0.4 0.5 0.2 0.5 0.3 0.3 0.4 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 TRBV7-7 "TCRBV6S6A2T, TCRBV7S7, TRBV77" ENSG00000253291 "T cell receptor beta variable 7-7" A0A0K0K1E9 7 142511626-142512127 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 15 "lymphoid tissue: 8.2" "Cell type enriched" "Detected in single" 11 "T-cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 7.8;memory CD8 T-cell: 2.5;naive CD4 T-cell: 7.6;naive CD8 T-cell: 3.3;T-reg: 10.1" "Lineage enriched" "Detected in single" 101 "T-cells: 10.1" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.82e-4)" "unprognostic (2.74e-1)" "unprognostic (1.93e-3)" "unprognostic (2.30e-2)" "unprognostic (1.89e-3)" "unprognostic (2.87e-1)" "unprognostic (1.04e-2)" "unprognostic (1.74e-2)" 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.1 0.0 8.2 0.0 0.0 1.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 7.8 2.5 0.0 0.0 7.6 3.3 0.0 0.0 0.0 0.0 10.1 2.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 TRBV7-9 "TCRBV6S4A1, TCRBV7S9, TRBV79" ENSG00000278030 "T cell receptor beta variable 7-9" P04435 7 142529290-142529762 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 55.4" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 9.2;Late spermatids: 5.4;T-cells: 22.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 37 "memory CD4 T-cell: 48.4;memory CD8 T-cell: 81.7;naive CD4 T-cell: 67.3;naive CD8 T-cell: 73.5;T-reg: 95.1" "Lineage enriched" "Detected in many" 87 "T-cells: 95.1" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 4.5;HBF TERT88: 1.2;U-2197: 1.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.18e-3)" "unprognostic (5.05e-3)" "unprognostic (6.66e-3)" "unprognostic (6.48e-5)" "unprognostic (1.04e-1)" "prognostic favorable (4.68e-5)" "unprognostic (1.12e-3)" "unprognostic (1.05e-2)" "unprognostic (7.15e-2)" "unprognostic (2.57e-3)" "unprognostic (6.40e-2)" "unprognostic (9.86e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (3.17e-1)" "unprognostic (6.65e-2)" "unprognostic (2.46e-2)" "unprognostic (1.06e-2)" 0.8 0.1 0.0 0.5 0.1 4.2 0.7 0.1 0.1 0.9 0.0 1.7 0.0 0.3 0.0 0.3 0.5 4.0 0.2 0.0 0.0 0.3 1.3 1.5 27.2 0.1 0.0 0.7 0.3 0.0 0.1 0.1 0.0 0.4 1.5 0.0 1.0 0.0 0.2 0.3 3.4 1.1 0.0 5.3 1.3 0.3 0.0 55.4 0.7 0.0 15.5 1.5 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 1.0 0.0 1.9 0.4 48.4 81.7 0.2 0.2 67.3 73.5 1.0 0.0 0.1 0.5 95.1 26.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 TRBV9 "TCRBV1S1A1N1, TCRBV9S1" ENSG00000211716 "T cell receptor beta variable 9" A0A0B4J1U6 7 142391891-142392412 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 9.1;testis: 2.6" "Group enriched" "Detected in some" 11 "Early spermatids: 5.8;Late spermatids: 4.8;T-cells: 7.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 20.0;memory CD8 T-cell: 21.7;naive CD4 T-cell: 14.8;naive CD8 T-cell: 13.2;T-reg: 27.2" "Lineage enriched" "Detected in single" 31 "T-cells: 27.2" "Group enriched" "Detected in some" 16 "HL-60: 3.4;LHCN-M2: 6.0;U-937: 13.3" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.28e-3)" "unprognostic (1.34e-2)" "unprognostic (1.73e-2)" "unprognostic (2.20e-3)" "unprognostic (3.00e-1)" "unprognostic (1.58e-4)" "unprognostic (8.88e-3)" "unprognostic (6.53e-2)" "unprognostic (1.20e-2)" "unprognostic (1.69e-3)" "unprognostic (2.98e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.60e-10)" "unprognostic (1.04e-1)" "unprognostic (7.94e-2)" "unprognostic (7.64e-3)" "unprognostic (1.46e-3)" 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.3 0.0 0.4 0.2 0.4 0.0 0.6 0.3 0.0 0.4 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.2 0.3 0.0 0.1 2.1 0.0 0.0 3.0 0.6 2.6 0.0 9.1 0.4 0.4 2.9 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 6.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 13.3 0.0 0.1 0.8 0.0 0.2 0.2 2.5 0.0 20.0 21.7 0.5 0.0 14.8 13.2 0.1 0.0 0.0 0.4 27.2 5.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 TRDV1 hDV101S1 ENSG00000211804 "T cell receptor delta variable 1" A0A1B0GX56 14 22096032-22096619 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "lymphoid tissue: 75.3" "Group enriched" "Detected in some" 8 "Plasma cells: 2.1;T-cells: 7.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 21 "gdT-cell: 1071.6" "Lineage enriched" "Detected in many" 198 "T-cells: 1071.6" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.59e-4)" "unprognostic (2.31e-3)" "unprognostic (1.49e-1)" "unprognostic (3.09e-3)" "unprognostic (3.18e-3)" "unprognostic (1.51e-2)" "unprognostic (4.21e-5)" "unprognostic (6.57e-2)" "unprognostic (1.83e-4)" "unprognostic (3.39e-1)" "unprognostic (2.21e-1)" "unprognostic (3.20e-3)" "unprognostic (1.04e-1)" "unprognostic (1.69e-1)" "unprognostic (2.01e-2)" "unprognostic (4.69e-2)" 0.3 0.2 0.0 2.1 0.0 1.0 0.3 0.0 0.0 0.5 0.0 4.6 0.5 0.2 0.0 0.1 0.3 2.6 0.0 0.0 0.0 0.3 0.8 3.4 10.3 0.1 0.0 1.3 0.0 0.0 0.0 0.1 0.1 0.2 2.6 0.0 0.3 0.6 0.3 0.1 0.7 0.1 0.0 20.0 1.8 1.3 0.0 75.3 1.1 0.0 5.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.4 1071.6 0.6 3.3 1.4 26.0 27.4 0.0 0.3 23.8 51.7 5.4 0.1 1.1 1.2 43.5 55.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 TRDV2 "hDV102S1, MGC117421" ENSG00000211821 "T cell receptor delta variable 2" A0JD36 14 22422371-22423042 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.2;lymphoid tissue: 3.4" "Cell type enriched" "Detected in some" 7 "T-cells: 24.5" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 218 "gdT-cell: 3222.2" "Lineage enriched" "Detected in all" 575 "T-cells: 3222.2" "Cell line enriched" "Detected in single" 25 "REH: 7.3" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 58: T-cells - T-cell receptor" 0.1 0.0 0.0 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.2 0.0 0.1 0.6 0.1 0.0 0.0 0.1 0.3 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 2.2 0.1 0.0 0.0 3.4 0.0 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 3.9 3222.2 4.4 1.6 2.1 1.9 14.7 5.6 0.4 1.7 4.2 5.1 1.3 0.8 2.3 5.9 384.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.6 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.5 0.0 0.0 0.0 TRDV3 hDV103S1 ENSG00000256590 "T cell receptor delta variable 3" A0JD37 14 22469041-22469698 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "epididymis: 12.5;lymphoid tissue: 9.2" "Cell type enhanced" "Detected in some" "Fibroblasts: 1.8;NK-cells: 1.0;T-cells: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 10 "gdT-cell: 63.4" "Lineage enriched" "Detected in single" 303 "T-cells: 63.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.31e-2)" "unprognostic (6.56e-2)" "unprognostic (1.43e-1)" 0.4 0.0 0.3 0.1 0.5 0.0 0.0 0.3 0.4 0.0 0.1 0.5 0.0 0.0 12.5 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.0 0.1 1.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.2 2.1 0.1 0.0 0.5 9.2 0.0 0.0 0.9 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 63.4 0.0 0.0 0.2 0.7 0.7 0.0 0.1 1.0 6.1 0.0 0.1 0.0 0.0 2.7 1.8 0.3 0.5 0.3 0.4 0.5 0.3 0.4 0.3 0.3 0.2 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 TREH "MGC129621, TRE, TREA" ENSG00000118094 Trehalase O43280 11 118657316-118679690 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 66.3" "Group enriched" "Detected in some" 5 "Late spermatids: 315.7;Proximal enterocytes: 186.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BEWO: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039913, HPA042045" Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" NA NA 12000000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA039913: AB_10674988, HPA042045: AB_2677817" "unprognostic (1.29e-1)" "unprognostic (1.58e-1)" "unprognostic (1.01e-2)" "unprognostic (5.22e-4)" "unprognostic (2.52e-1)" "unprognostic (9.83e-2)" "prognostic favorable (3.76e-4)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (2.42e-1)" "unprognostic (1.04e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.33e-6)" "unprognostic (2.09e-2)" "unprognostic (6.30e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-1)" 0.7 0.2 1.6 0.3 3.7 0.0 0.4 0.6 3.8 0.3 0.0 1.6 60.0 0.4 0.6 1.6 0.3 2.6 1.0 1.1 2.7 13.4 6.1 0.2 0.1 2.1 2.0 0.2 1.8 0.0 0.3 0.1 1.9 0.5 1.3 0.0 0.2 0.0 0.0 0.1 66.3 0.1 0.6 0.1 1.7 1.8 2.5 0.0 0.4 0.0 0.0 0.4 0.3 6.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.7 0.6 3.8 1.1 2.7 2.1 2.0 1.9 0.6 2.5 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.3 0.3 1.5 0.0 1.8 0.0 0.1 0.0 2.3 7.9 0.2 45.6 0.8 1.6 0.1 3.0 0.0 0.1 2.5 0.0 0.3 4.6 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 7.0 0.0 0.0 0.4 315.7 2.1 0.1 0.0 0.0 0.0 0.0 0.0 1.5 5.3 0.9 6.3 1.9 0.1 0.3 186.3 32.8 0.0 0.0 0.0 0.3 0.2 1.7 0.8 2.1 0.0 0.0 0.1 0.0 3.7 0.0 TREM1 "CD354, TREM-1" ENSG00000124731 "Triggering receptor expressed on myeloid cells 1" Q9NP99 6 41267926-41286682 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 96.0;lung: 65.3;lymphoid tissue: 44.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 26.1;Hofbauer cells: 25.1;Kupffer cells: 35.5;Langerhans cells: 21.5;Late spermatids: 20.6;Macrophages: 104.2;monocytes: 19.9" "Cancer enhanced" "Detected in many" "lung cancer: 9.6" "Region enhanced" "Detected in some" "cerebral cortex: 8.5" "Immune cell enriched" "Detected in many" 7 "neutrophil: 615.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 615.1" "Group enriched" "Detected in some" 4 "SuSa: 6.2;U-87 MG: 24.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005563, HPA053612" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA005563: AB_1858259, HPA053612: " "unprognostic (6.41e-2)" "unprognostic (1.47e-3)" "unprognostic (1.22e-1)" "unprognostic (3.39e-2)" "unprognostic (6.07e-3)" "unprognostic (2.97e-2)" "unprognostic (5.73e-5)" "unprognostic (1.29e-1)" "unprognostic (1.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.24e-3)" "unprognostic (7.65e-2)" "unprognostic (3.18e-7)" "unprognostic (6.32e-3)" "unprognostic (4.95e-2)" "unprognostic (1.08e-1)" "unprognostic (7.26e-2)" 20.4 1.4 0.4 44.1 0.4 96.0 1.2 0.4 8.5 0.8 2.3 0.9 0.4 2.2 0.0 1.5 3.9 9.9 3.8 0.4 0.6 1.1 6.9 65.3 0.4 0.9 0.7 0.5 3.9 1.1 2.4 7.7 1.9 0.7 0.3 0.6 1.2 0.5 0.5 0.2 1.0 8.4 0.6 11.1 0.8 0.3 2.6 3.1 0.7 2.6 1.3 12.6 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 6.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 1.6 0.0 0.1 82.7 2.3 0.0 20.7 0.1 0.6 0.1 0.0 32.8 1.5 0.2 0.0 615.1 0.2 10.1 0.7 0.0 32.5 0.4 0.4 0.4 8.5 0.4 0.6 0.9 0.7 1.9 0.6 2.6 0.9 0.0 6.4 26.1 0.0 1.8 0.4 0.4 5.4 0.0 0.0 0.1 0.1 0.3 2.8 12.4 0.0 0.0 0.4 0.3 0.1 0.0 0.3 12.1 0.3 1.8 3.8 0.0 0.0 0.0 0.2 1.1 2.5 1.1 0.1 6.3 0.0 0.7 0.5 25.1 0.0 0.0 0.0 2.0 35.5 21.5 20.6 0.0 104.2 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.2 0.2 0.0 0.3 13.3 0.1 0.0 0.8 2.8 0.0 0.1 0.0 0.1 14.6 2.0 0.0 0.0 0.1 TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 1014.1" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Group enriched" "Detected in some" 4 "hTCEpi: 74.6;THP-1: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" 10.7 13.2 28.1 3.5 31.1 0.2 9.8 33.7 61.5 6.5 29.1 3.5 0.9 1.6 2.3 0.6 7.4 9.7 2.1 27.5 32.3 1.3 2.3 30.1 2.6 44.5 34.4 2.4 3.9 7.4 3.9 10.7 42.7 2.0 4.3 1.9 6.0 3.1 0.4 0.5 1.4 4.5 46.7 0.5 2.5 0.7 43.5 1.8 1.7 0.0 0.4 4.5 0.6 69.8 0.0 0.3 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 1.2 74.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 42.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 28.1 31.1 33.7 61.5 27.5 32.3 44.5 34.4 42.7 46.7 43.5 69.8 1.8 6.4 7.5 0.0 0.7 0.8 0.2 79.8 0.0 0.3 1.8 58.8 0.1 1.5 9.6 0.0 0.0 5.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 10.4 0.0 0.0 0.0 0.0 4.9 1.2 0.0 0.0 2.5 0.0 2.2 0.2 1014.1 0.0 0.0 0.0 2.0 34.7 5.2 1.0 0.6 120.5 0.0 12.2 8.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 3.3 1.0 6.6 0.1 1.0 0.0 0.0 0.0 0.1 7.3 0.8 0.0 0.0 0.1 TRGV1 "TCRGV1, V1S1P" ENSG00000211701 "T cell receptor gamma variable 1 (non-functional)" 7 38367586-38368169 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 1.0;HL-60: 1.6;JURKAT: 1.4;Karpas-707: 2.1;U-937: 2.6" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" 0.1 0.0 0.2 0.6 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 1.4 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 1.5 0.2 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.4 0.5 1.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.7 2.1 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.3 0.1 2.6 0.0 0.0 0.6 0.0 1.8 0.1 1.8 0.1 0.8 1.2 0.2 0.0 0.2 0.8 0.0 1.7 0.0 0.6 0.0 0.4 0.2 0.1 0.1 0.2 0.0 0.1 0.5 0.6 0.2 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 TRGV10 "TCRGV10, V3P" ENSG00000211694 "T cell receptor gamma variable 10 (non-functional)" 7 38299811-38300322 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 13.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.5;Plasma cells: 7.1;T-cells: 29.9" "Cancer enriched" "Detected in many" 8 "prostate cancer: 7.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 196.5" "Lineage enriched" "Detected in many" 8 "T-cells: 196.5" "Group enriched" "Detected in some" 24 "NB-4: 79.7;U-937: 20.5" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.59e-2)" "unprognostic (4.53e-3)" "unprognostic (5.13e-2)" "unprognostic (2.94e-3)" "unprognostic (1.54e-2)" "unprognostic (1.22e-4)" "unprognostic (2.47e-3)" "unprognostic (2.24e-1)" "unprognostic (2.50e-2)" "unprognostic (2.53e-2)" "unprognostic (1.94e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-4)" "unprognostic (2.68e-1)" "unprognostic (9.00e-2)" "unprognostic (5.10e-2)" "unprognostic (2.07e-2)" 1.7 0.6 0.1 2.7 0.3 14.1 1.8 0.1 0.4 1.2 0.6 2.0 2.1 0.8 0.7 1.1 1.3 3.3 0.4 0.0 0.1 0.6 1.8 4.1 11.0 0.4 0.1 0.3 0.2 0.1 0.2 0.4 0.3 6.1 2.7 0.0 1.1 0.7 0.2 0.6 4.1 0.6 0.2 13.9 2.6 0.3 0.2 12.5 1.1 0.0 5.0 3.8 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 79.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 20.5 0.0 0.7 0.4 1.0 196.5 0.1 156.1 0.5 47.2 137.6 0.2 0.1 11.3 159.7 2.9 26.0 0.3 0.8 0.1 33.3 0.1 0.3 0.1 0.4 0.0 0.1 0.4 0.1 0.3 0.2 0.2 0.3 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 29.9 0.0 0.0 0.0 TRGV2 "TCRGV2, VIS2" ENSG00000233306 "T cell receptor gamma variable 2" A0A075B6R0 7 38362864-38363518 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 6.6" "Cell type enriched" "Detected in some" 5 "T-cells: 19.2" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 147.8" "Lineage enriched" "Detected in many" 22 "T-cells: 147.8" "Cell line enriched" "Detected in some" 4 "Karpas-707: 17.4" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.51e-3)" "unprognostic (8.88e-5)" "unprognostic (1.77e-1)" "unprognostic (1.01e-2)" "unprognostic (1.72e-1)" "unprognostic (4.31e-4)" "unprognostic (1.50e-3)" "unprognostic (1.13e-1)" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (7.48e-2)" "unprognostic (3.02e-1)" "unprognostic (4.21e-5)" "unprognostic (1.43e-2)" "unprognostic (1.96e-1)" "unprognostic (1.25e-1)" "unprognostic (4.87e-3)" 0.4 0.6 0.0 1.6 0.0 0.9 0.1 0.0 0.2 0.2 0.2 0.8 0.8 0.3 0.1 0.1 0.3 1.0 0.2 0.0 0.0 0.1 0.3 0.9 5.0 0.7 0.4 0.0 0.1 0.0 0.1 0.0 0.2 1.2 0.6 0.1 0.9 0.1 0.1 0.2 1.4 0.4 0.1 6.6 0.7 0.3 0.4 4.8 0.3 0.0 0.7 0.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 2.4 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 1.0 17.4 0.0 0.0 0.5 0.8 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.7 1.7 0.1 0.0 3.8 0.0 0.2 0.4 0.0 59.4 0.2 58.4 0.1 29.7 147.8 1.4 0.2 7.0 54.9 0.9 6.8 0.1 1.5 0.6 22.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.4 0.2 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 TRGV3 "TCRGV3, V1S3" ENSG00000211699 "T cell receptor gamma variable 3" P03979 7 38358512-38359162 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 12.4" "Cell type enhanced" "Detected in some" "dendritic cells: 1.8;Plasma cells: 2.6;T-cells: 5.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "gdT-cell: 59.0" "Lineage enriched" "Detected in many" 5 "T-cells: 59.0" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;JURKAT: 12.1;Karpas-707: 28.9;U-266/84: 5.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.87e-2)" "unprognostic (1.63e-3)" "unprognostic (4.58e-2)" "unprognostic (6.48e-3)" "unprognostic (4.66e-2)" "unprognostic (1.57e-3)" "unprognostic (2.28e-1)" "unprognostic (1.72e-2)" "unprognostic (1.49e-1)" "unprognostic (4.46e-2)" "unprognostic (4.75e-2)" "unprognostic (1.46e-1)" "unprognostic (5.26e-3)" "unprognostic (2.28e-1)" "unprognostic (3.46e-2)" "unprognostic (3.71e-2)" "unprognostic (3.42e-2)" 0.6 0.3 0.1 1.3 0.1 2.8 0.5 0.1 0.2 0.7 0.1 1.8 1.0 0.6 0.0 0.5 0.6 3.9 0.3 0.1 0.3 0.4 0.7 1.4 12.4 0.7 1.3 0.1 0.2 0.3 0.2 1.0 0.4 1.3 1.9 0.0 1.1 0.4 0.1 0.3 3.1 0.7 0.5 7.6 1.3 0.5 0.5 9.3 0.4 0.0 8.9 2.0 0.3 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 7.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 3.8 12.1 0.7 28.9 0.0 0.2 0.0 1.4 0.2 0.0 0.0 1.5 1.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 3.1 0.8 0.0 0.0 0.0 0.1 3.0 5.9 0.4 0.1 1.6 0.0 0.1 1.6 0.0 59.0 0.7 50.1 3.4 11.0 34.0 5.7 1.8 9.4 27.6 0.1 11.4 2.2 11.1 6.3 8.0 0.1 0.1 0.1 0.2 0.1 0.3 0.7 1.3 0.4 0.5 0.5 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 TRGV4 "TCRGV4, V1S4" ENSG00000211698 "T cell receptor gamma variable 4" A0A0C4DH28 7 38353715-38354517 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 11.1" "Cell type enhanced" "Detected in some" "dendritic cells: 2.7;Plasma cells: 2.1;T-cells: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "gdT-cell: 97.8" "Lineage enriched" "Detected in many" 15 "T-cells: 97.8" "Cell line enriched" "Detected in some" 4 "Karpas-707: 72.0" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (7.44e-3)" "unprognostic (7.26e-3)" "unprognostic (5.77e-2)" "unprognostic (1.90e-2)" "unprognostic (3.58e-1)" "unprognostic (6.75e-3)" "unprognostic (9.66e-2)" "unprognostic (8.83e-3)" "unprognostic (1.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.42e-2)" "unprognostic (1.58e-1)" "unprognostic (2.59e-3)" "unprognostic (2.24e-1)" "unprognostic (1.14e-1)" "unprognostic (2.47e-2)" "unprognostic (3.71e-3)" 0.4 0.4 0.2 0.4 0.2 3.0 0.4 0.3 0.2 0.3 0.8 1.6 0.4 0.4 0.2 0.4 0.5 2.2 0.2 0.2 0.2 0.4 1.4 1.7 11.1 0.8 1.2 0.1 0.1 0.1 0.2 0.4 0.5 1.9 1.4 0.0 0.9 0.3 0.1 0.5 3.5 0.3 0.4 9.0 1.6 0.7 0.9 7.1 0.4 0.0 4.9 0.8 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 13.9 0.1 8.3 0.0 0.0 0.0 4.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 8.3 4.6 72.0 0.1 0.2 0.0 16.8 0.4 0.0 0.1 0.6 0.9 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.2 0.0 0.0 0.0 2.7 1.9 0.0 1.1 14.5 0.0 0.2 1.5 0.1 97.8 0.3 30.1 1.0 4.4 26.8 1.7 0.6 2.0 23.8 0.6 6.5 0.1 5.8 1.4 7.2 0.2 0.2 0.3 0.2 0.2 0.2 0.8 1.2 0.5 0.4 0.9 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 TRGV5 "TCRGV5, V1S5" ENSG00000211697 "T cell receptor gamma variable 5" A0A0B4J1U4 7 38349355-38350022 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.0" "Cell type enhanced" "Detected in some" "dendritic cells: 2.4;Hepatic stellate cells: 1.8;Hofbauer cells: 2.9;Kupffer cells: 7.2;Plasma cells: 2.5;T-cells: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HDLM-2: 6.9;JURKAT: 11.1;Karpas-707: 15.2;NB-4: 4.7;U-266/84: 4.9;U-87 MG: 6.8;U-937: 6.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.17e-2)" "unprognostic (1.21e-2)" "unprognostic (6.61e-2)" "unprognostic (2.62e-4)" "unprognostic (5.91e-3)" "unprognostic (1.66e-2)" "unprognostic (3.18e-2)" "unprognostic (3.00e-1)" "unprognostic (3.42e-2)" "unprognostic (2.88e-1)" "unprognostic (2.39e-2)" "unprognostic (1.06e-1)" "unprognostic (7.73e-6)" "unprognostic (1.62e-1)" "unprognostic (2.35e-1)" "unprognostic (1.69e-1)" "unprognostic (3.77e-2)" 0.4 0.4 0.0 0.9 0.0 2.3 0.4 0.0 0.0 0.5 0.1 1.2 0.0 0.2 0.1 0.3 0.2 1.9 0.3 0.0 0.0 0.4 1.1 1.2 3.7 0.4 0.7 0.2 0.0 0.0 0.1 0.6 0.3 0.8 1.0 0.0 0.6 0.1 0.2 0.3 1.0 0.6 0.1 3.6 0.8 0.2 0.3 6.0 0.3 0.3 4.7 1.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.3 0.4 1.4 0.0 0.0 0.0 0.0 6.9 0.8 1.9 0.0 0.0 0.0 2.1 1.3 0.2 0.0 0.0 0.0 0.0 0.5 11.1 0.2 15.2 0.1 0.3 0.0 4.7 0.0 0.0 0.0 0.4 0.7 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.8 0.0 0.4 0.1 0.1 0.0 0.0 4.9 0.4 6.8 6.9 0.0 0.0 5.1 0.6 24.5 1.7 20.1 0.7 2.9 22.4 5.6 0.7 1.4 9.5 0.3 8.2 0.2 6.9 3.7 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 1.8 0.0 2.9 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.0 0.0 0.1 6.0 0.0 0.0 0.0 TRGV8 "TCRGV8, V1S8" ENSG00000211696 "T cell receptor gamma variable 8" A0A0C4DH27 7 38330343-38330935 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.8;prostate: 4.9" "Cell type enriched" "Detected in some" 4 "T-cells: 12.5" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 3.1" "Group enriched" "Detected in many" 6 "gdT-cell: 34.4;MAIT T-cell: 40.6;memory CD8 T-cell: 31.1;naive CD8 T-cell: 17.2" "Lineage enriched" "Detected in many" 7 "T-cells: 40.6" "Cell line enriched" "Detected in some" 4 "JURKAT: 44.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.3 0.3 0.3 1.5 0.0 0.7 0.3 0.0 0.2 0.4 0.0 0.8 0.8 0.7 0.6 0.6 0.9 1.2 0.3 0.5 0.1 0.2 1.4 2.3 3.5 1.0 3.1 0.3 0.3 0.1 0.0 1.4 1.0 4.9 1.2 0.0 0.3 0.4 0.1 0.0 1.9 0.9 0.2 6.8 0.7 0.4 0.4 4.5 0.2 0.0 2.0 1.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 2.4 0.1 0.5 0.0 0.0 0.9 0.0 0.3 0.2 0.0 0.0 0.0 2.1 3.1 0.0 1.4 0.0 0.0 0.0 3.6 0.5 0.0 0.0 1.2 0.0 0.0 0.0 44.9 1.0 2.5 0.0 0.7 0.0 1.7 0.0 0.0 0.0 3.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.0 2.7 10.6 0.0 0.0 0.7 0.0 34.4 0.1 40.6 0.0 3.7 31.1 0.9 0.0 0.2 17.2 0.2 5.5 0.1 0.2 0.1 4.5 0.3 0.0 0.0 0.2 0.5 0.1 1.0 3.1 1.0 0.2 0.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.3 0.0 0.0 TRGV9 "TCRGV9, V2" ENSG00000211695 "T cell receptor gamma variable 9" Q99603 7 38317017-38318861 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.9;prostate: 5.5" "Group enriched" "Detected in some" 4 "dendritic cells: 14.6;NK-cells: 22.6;T-cells: 37.7" "Cancer enriched" "Detected in single" 126 "prostate cancer: 13.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 13 "gdT-cell: 426.5" "Lineage enriched" "Detected in many" 13 "T-cells: 426.5" "Group enriched" "Detected in some" 6 "MCF7: 7.7;NB-4: 2.4;U-937: 8.6" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 19: Lung - Lung function" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.07e-1)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (3.98e-3)" "unprognostic (4.43e-2)" "unprognostic (4.13e-2)" "unprognostic (1.29e-2)" "unprognostic (2.06e-1)" "unprognostic (1.83e-1)" "unprognostic (1.47e-1)" "unprognostic (1.51e-3)" "unprognostic (2.41e-1)" "unprognostic (6.60e-4)" "unprognostic (1.29e-1)" "unprognostic (4.95e-1)" 0.4 0.0 0.4 0.5 0.7 1.1 0.1 0.4 0.5 0.1 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.5 0.5 0.0 0.2 0.4 0.5 0.7 0.5 0.0 0.1 0.0 0.0 1.9 0.7 5.5 0.2 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.4 1.6 0.3 0.1 0.5 1.5 0.0 0.0 0.4 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 7.7 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.6 0.0 0.0 0.3 0.1 426.5 0.6 29.0 0.1 1.6 19.7 0.4 0.0 0.7 8.4 1.4 33.2 0.1 0.5 0.1 38.8 0.4 0.7 0.4 0.5 0.5 0.5 0.7 0.5 0.7 0.4 0.5 0.8 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 4.6 0.0 0.0 0.1 1.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 0.0 0.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 TRH ENSG00000170893 "Thyrotropin releasing hormone" P20396 3 129974688-129977935 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 68.7;cervix: 26.0;endometrium 1: 18.7;retina: 35.2" "Cell type enriched" "Detected in some" 10 "Muller glia cells: 234.5" "Group enriched" "Detected in some" 5 "breast cancer: 13.3;endometrial cancer: 10.2;glioma: 4.3" "Group enriched" "Detected in many" 6 "hypothalamus: 68.7;medulla oblongata: 59.4;pons: 38.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.0" "Group enriched" "Detected in many" 5 "hypothalamus: 175.6;olfactory bulb: 148.0" "Low region specificity" "Detected in many" HPA035596 Enhanced "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 5: Muller glia cells - Visual perception" "HPA035596: AB_2674695" "unprognostic (1.22e-1)" "unprognostic (8.94e-2)" "unprognostic (5.82e-3)" "unprognostic (5.24e-2)" "unprognostic (2.82e-1)" "unprognostic (1.11e-1)" "unprognostic (1.84e-1)" "unprognostic (4.44e-2)" "unprognostic (3.86e-2)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.95e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" 0.2 0.0 4.9 0.1 0.9 3.7 1.9 2.2 0.8 26.0 0.1 0.0 0.1 18.7 0.0 0.0 2.5 0.0 0.5 2.3 68.7 0.5 0.0 0.6 0.0 59.4 9.1 3.8 0.0 0.0 0.2 0.2 38.2 0.1 0.0 35.2 0.5 0.1 0.1 0.4 0.0 0.3 2.8 0.1 0.0 1.2 3.7 0.4 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.9 0.9 2.2 0.8 2.3 68.7 59.4 9.1 38.2 2.8 3.7 0.7 0.3 0.0 0.0 0.3 0.2 0.8 0.7 0.0 0.0 10.4 1.6 1.4 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 7.1 9.0 0.8 0.7 0.0 0.0 0.2 0.0 0.1 0.2 0.0 22.5 0.0 0.1 0.0 0.0 0.1 5.0 0.3 0.0 0.0 0.0 11.5 2.7 0.0 2.0 0.0 0.0 0.0 234.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 9.2 0.0 0.0 0.2 0.7 1.6 0.0 0.1 0.1 0.2 0.1 0.0 4.3 TRIM24 "hTIF1, RNF82, TIF1, Tif1a" ENSG00000122779 "Tripartite motif containing 24" O15164 7 138460259-138589996 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "AF22: 146.5;HMC-1: 196.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043495, HPA061717" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA043495: AB_10962915, HPA061717: AB_2684592" "unprognostic (2.40e-1)" "unprognostic (9.52e-3)" "unprognostic (2.23e-1)" "unprognostic (3.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.94e-4)" "prognostic favorable (6.57e-4)" "unprognostic (4.01e-2)" "unprognostic (8.93e-2)" "unprognostic (2.53e-1)" "unprognostic (2.02e-1)" "unprognostic (4.62e-2)" "unprognostic (1.62e-1)" "unprognostic (2.25e-2)" "unprognostic (5.54e-2)" "unprognostic (6.34e-2)" 7.5 25.7 6.0 6.9 6.8 10.6 9.1 5.8 7.0 6.4 5.2 8.1 10.0 8.8 8.4 9.0 5.7 5.3 10.4 6.0 7.1 8.0 23.1 11.4 8.0 6.8 6.4 30.0 10.8 14.2 3.8 12.3 6.3 11.7 9.2 12.2 8.3 5.2 13.9 8.6 9.7 7.6 6.2 7.2 11.6 27.3 8.2 17.3 9.1 16.4 7.8 7.5 6.1 9.0 15.0 18.1 146.5 42.7 9.6 8.9 11.4 13.7 14.4 10.5 10.2 28.7 13.6 28.7 13.2 13.2 21.5 7.9 71.9 11.4 15.4 22.1 17.7 63.1 13.1 88.9 13.1 49.8 196.8 7.9 11.8 8.8 13.9 7.3 25.0 15.4 72.6 17.1 12.7 29.2 85.2 44.8 56.3 77.6 16.0 66.5 17.3 24.2 23.6 43.9 30.3 68.8 25.5 22.6 7.5 50.6 15.5 32.3 10.7 12.1 9.9 21.4 19.1 15.6 18.2 47.8 20.1 32.1 18.0 0.3 0.6 1.0 0.5 0.6 0.1 0.2 0.4 0.3 0.5 0.3 0.4 0.5 0.9 0.6 0.3 0.3 0.7 0.2 6.0 6.8 5.8 7.0 6.0 7.1 6.8 6.4 6.3 6.2 8.2 9.0 29.0 51.3 46.9 26.1 9.5 13.9 13.4 13.8 10.8 13.6 14.7 14.4 39.7 20.0 18.8 7.3 16.7 28.4 14.9 12.2 5.9 7.1 70.4 16.7 22.9 18.9 10.1 31.3 27.9 12.4 15.2 16.0 20.4 25.2 40.4 85.2 14.3 31.9 10.3 40.4 46.6 10.9 14.2 9.5 14.9 38.7 14.0 13.8 14.2 21.5 12.2 23.3 9.2 64.3 67.1 9.5 9.5 16.1 13.7 12.2 6.8 10.6 14.5 22.4 13.1 21.5 17.6 72.8 14.7 22.2 11.8 22.2 15.8 34.6 19.4 12.8 TRIM28 "KAP1, PPP1R157, RNF96, TF1B, TIF1B" ENSG00000130726 "Tripartite motif containing 28" Q13263 19 58544064-58550722 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 2817.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010066, HPA064033" Supported Enhanced Nucleoplasm "Intracellular and membrane" NA NA 140000 "Cluster 15: NK-cells - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB010066: AB_2209905, HPA064033: AB_2685179" "unprognostic (2.76e-1)" "unprognostic (1.40e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (1.85e-6)" "unprognostic (1.20e-2)" "unprognostic (2.10e-2)" "unprognostic (2.66e-1)" "unprognostic (4.92e-3)" "unprognostic (9.28e-2)" "unprognostic (2.47e-2)" "unprognostic (4.67e-2)" "unprognostic (7.34e-2)" "unprognostic (4.22e-1)" "unprognostic (3.28e-2)" 103.1 111.0 83.5 103.8 85.9 217.5 104.4 91.1 100.1 152.9 77.5 159.9 90.8 163.3 42.8 132.6 142.8 73.6 114.7 83.1 80.1 122.1 104.6 103.5 142.5 85.5 83.4 228.1 183.7 89.4 98.7 108.9 89.1 128.8 57.8 39.4 108.4 108.8 172.4 143.3 117.7 94.6 86.0 137.4 136.7 215.5 82.8 186.6 117.9 77.0 109.2 147.7 115.1 97.2 481.6 1080.4 491.9 365.1 218.9 186.5 616.5 321.5 291.1 311.4 237.0 732.8 375.0 562.5 196.1 270.7 492.8 317.7 590.5 480.5 163.6 281.3 2817.1 1012.8 407.6 537.7 254.4 640.9 577.5 252.4 248.2 385.9 274.9 220.1 301.3 597.7 507.1 259.4 284.8 705.0 756.5 640.8 372.8 443.6 637.5 761.9 340.9 550.2 260.8 730.6 517.1 403.4 343.9 359.3 170.7 131.9 273.2 493.1 272.4 643.1 273.2 148.6 562.5 397.7 665.7 604.7 293.0 432.9 418.6 1.9 9.7 8.2 12.8 11.1 17.2 15.9 18.0 17.4 13.7 19.1 22.8 20.5 4.3 24.9 7.9 21.2 12.4 10.1 83.5 85.9 91.1 100.1 83.1 80.1 85.5 83.4 89.1 86.0 82.8 97.2 60.8 12.8 18.6 18.3 51.0 64.2 60.2 34.7 47.3 61.8 86.6 87.5 9.5 51.5 29.0 33.1 27.1 61.2 72.4 88.3 23.5 44.8 96.9 70.7 53.3 49.7 64.6 46.7 10.3 56.3 61.6 48.3 65.7 80.2 21.6 136.3 35.7 31.9 46.9 55.5 12.6 79.4 14.2 36.5 70.7 110.6 65.9 48.3 28.4 6.5 32.8 49.8 19.6 10.6 18.2 56.3 50.0 41.3 43.5 52.1 47.3 36.3 28.7 34.1 59.2 69.3 61.6 158.7 83.1 58.0 60.7 56.1 54.5 80.9 94.1 45.6 TRIM39 RNF23 ENSG00000204599 "Tripartite motif containing 39" Q9HCM9 6 30326479-30343729 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051120, HPA059496" Uncertain Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA051120: AB_2681348, HPA059496: AB_2684040" "unprognostic (2.90e-1)" "unprognostic (1.61e-2)" "unprognostic (2.79e-2)" "unprognostic (2.86e-2)" "unprognostic (6.38e-2)" "unprognostic (4.55e-2)" "unprognostic (1.46e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-1)" "unprognostic (9.44e-2)" "prognostic favorable (2.50e-4)" "unprognostic (1.30e-2)" "unprognostic (4.69e-2)" "unprognostic (6.35e-3)" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (2.39e-3)" 10.0 8.7 0.8 1.7 1.0 3.1 10.2 1.3 1.1 11.4 1.5 13.6 1.6 12.1 2.2 13.1 11.7 1.3 8.7 0.9 0.9 9.8 11.6 9.7 1.6 1.3 1.0 11.5 12.2 2.1 14.8 1.6 1.0 10.8 1.5 1.5 10.2 2.0 14.3 9.3 11.9 1.8 0.8 14.3 11.0 20.7 1.1 1.7 11.6 1.4 2.1 12.9 9.5 1.1 3.2 0.1 2.6 4.8 1.2 1.2 2.7 1.4 1.8 2.1 1.9 3.8 0.4 4.1 2.8 2.7 1.3 1.0 3.1 2.2 2.2 3.2 3.4 3.2 0.5 1.4 2.7 4.8 3.5 1.4 1.8 2.7 2.9 3.2 1.3 3.4 4.9 3.2 2.7 2.9 1.0 1.0 3.6 1.3 2.2 2.2 0.5 3.1 2.2 3.0 5.7 2.8 1.1 2.3 2.8 2.5 3.1 1.2 1.2 2.3 1.8 2.8 4.9 5.7 7.6 4.2 1.3 1.7 3.6 1.0 0.9 4.1 2.7 1.3 2.4 1.8 1.9 2.0 0.9 1.6 2.2 2.2 4.5 2.6 1.4 0.7 1.7 1.4 0.8 1.0 1.3 1.1 0.9 0.9 1.3 1.0 1.0 0.8 1.1 1.1 5.9 3.2 7.2 0.7 14.2 3.7 5.6 2.6 6.8 6.0 7.5 5.2 5.6 2.8 3.5 1.8 6.2 4.7 11.9 5.5 7.9 4.6 4.6 11.2 4.1 4.8 5.4 3.6 0.9 6.1 5.7 4.1 15.3 13.1 5.7 4.2 5.7 3.7 3.3 3.3 1.1 7.3 4.1 7.2 5.0 7.8 2.8 7.3 3.6 1.0 4.3 6.9 8.2 0.5 0.9 6.8 10.0 4.5 10.9 3.7 7.5 4.0 7.2 7.6 0.0 3.8 5.8 19.1 10.0 5.3 4.1 10.0 15.3 3.5 4.4 5.3 TRIM65 ENSG00000141569 "Tripartite motif containing 65" Q6PJ69 17 75880335-75896951 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021575, HPA021578, HPA064820" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Cytosol" "HPA021575: AB_1858314, HPA021578: AB_1858315, HPA064820: AB_2685359" "unprognostic (1.82e-1)" "unprognostic (1.47e-1)" "unprognostic (3.47e-2)" "unprognostic (1.36e-1)" "unprognostic (1.96e-1)" "unprognostic (1.36e-2)" "prognostic unfavorable (4.74e-6)" "unprognostic (5.36e-2)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (5.82e-2)" "unprognostic (6.00e-3)" "prognostic unfavorable (1.82e-5)" "unprognostic (2.86e-3)" "unprognostic (7.18e-2)" "unprognostic (4.24e-3)" "unprognostic (7.50e-3)" 13.0 7.8 12.5 8.5 15.2 7.4 10.7 15.3 13.5 15.5 11.0 14.1 8.8 14.7 6.8 14.2 13.1 7.1 10.3 11.5 13.2 11.2 8.4 12.9 10.5 15.0 14.6 14.1 15.7 7.4 11.8 5.4 14.8 11.7 7.9 7.2 12.6 8.1 13.2 14.6 13.5 8.3 13.8 16.6 11.3 3.9 14.5 6.5 12.2 6.9 8.2 14.6 14.0 17.0 19.8 20.2 7.8 22.2 13.5 19.2 4.0 8.3 8.9 11.1 9.4 9.1 17.0 21.4 6.5 7.2 15.6 13.7 16.8 18.6 6.8 11.1 28.9 16.9 20.4 12.5 13.4 17.2 18.9 12.0 14.4 8.9 16.0 9.3 29.2 27.2 29.3 19.5 8.7 20.6 38.0 33.7 17.7 20.0 19.5 31.3 11.2 30.9 11.2 8.2 16.1 14.9 11.4 21.3 22.7 9.7 21.2 24.2 14.5 26.6 13.5 13.3 16.9 17.9 7.4 6.2 16.2 32.2 11.8 1.4 1.1 1.8 1.9 1.0 2.2 1.4 1.4 1.9 0.9 2.0 1.5 1.5 1.1 1.9 0.6 1.3 1.3 0.6 12.5 15.2 15.3 13.5 11.5 13.2 15.0 14.6 14.8 13.8 14.5 17.0 8.4 6.4 4.8 13.1 7.5 2.9 5.7 2.4 3.4 19.0 3.7 3.0 4.3 5.7 3.4 9.2 12.5 0.9 9.0 3.6 1.9 3.2 0.4 2.8 9.2 8.2 0.0 9.5 4.5 3.4 3.6 6.6 7.1 4.0 7.0 8.6 5.7 3.8 8.9 5.0 5.9 6.6 6.1 5.4 9.3 0.5 13.7 6.9 8.8 3.7 4.9 6.3 3.1 6.6 9.3 5.3 2.9 9.4 5.8 5.1 4.8 5.9 1.8 12.9 0.0 9.3 5.2 0.8 2.9 6.7 3.7 0.5 8.5 6.4 5.9 2.8 TRIM66 "C11orf29, KIAA0298, TIF1D" ENSG00000166436 "Tripartite motif containing 66" O15016 11 8612037-8682694 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Early spermatids: 46.0;Late spermatids: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027420 Approved Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA027420: AB_1858316" "unprognostic (1.26e-1)" "unprognostic (1.97e-1)" "unprognostic (2.43e-1)" "unprognostic (7.54e-2)" "unprognostic (3.99e-2)" "unprognostic (1.37e-3)" "unprognostic (8.01e-2)" "unprognostic (1.18e-1)" "unprognostic (8.49e-2)" "unprognostic (6.79e-2)" "prognostic favorable (8.89e-4)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.96e-4)" "unprognostic (1.67e-1)" "unprognostic (4.26e-1)" "unprognostic (4.67e-2)" "unprognostic (4.31e-1)" 4.4 5.9 4.5 4.0 5.6 2.8 4.6 2.8 4.6 3.9 5.2 4.4 3.5 3.8 8.2 5.2 4.2 3.0 2.4 3.0 5.1 4.9 10.9 3.6 5.3 4.1 5.4 3.6 8.9 3.1 9.5 1.5 4.0 4.2 4.6 3.6 4.3 3.3 3.6 11.9 5.5 3.5 3.3 5.7 5.4 17.3 5.4 4.5 6.2 3.1 5.2 4.2 4.2 3.6 5.3 4.9 2.9 10.2 6.0 4.5 3.6 3.2 3.7 2.2 2.9 6.5 9.9 5.2 2.2 2.9 2.1 7.2 3.1 2.8 2.7 6.1 2.4 5.0 9.2 3.6 2.5 4.5 3.9 7.1 2.8 1.9 6.6 2.4 2.9 13.1 2.7 5.5 2.9 5.8 2.1 3.4 1.8 2.7 4.6 3.0 2.2 2.1 3.1 6.7 2.1 2.0 4.6 3.2 2.2 2.8 4.2 1.0 2.3 4.2 3.8 2.5 2.8 2.3 3.7 6.4 2.8 4.6 2.4 0.0 0.5 0.6 0.7 0.1 0.4 0.6 0.7 0.9 0.7 0.8 0.7 1.1 0.3 0.8 1.3 1.3 0.6 0.3 4.5 5.6 2.8 4.6 3.0 5.1 4.1 5.4 4.0 3.3 5.4 3.6 3.0 3.2 5.6 47.7 4.0 1.8 2.3 3.6 2.2 8.0 5.1 5.6 1.9 4.3 5.1 5.5 12.5 3.6 3.1 4.5 0.0 3.4 46.0 5.0 4.0 3.2 6.0 5.7 14.2 3.2 1.8 2.6 5.1 3.7 1.3 6.7 5.0 9.8 2.6 11.8 17.1 4.2 0.0 5.2 2.2 27.3 1.8 3.8 0.0 13.1 5.9 4.3 3.1 9.5 22.6 3.9 3.9 2.2 3.1 1.6 8.3 2.4 5.4 9.0 13.1 6.5 2.5 14.6 7.2 3.8 1.1 1.4 3.3 8.0 4.4 1.0 TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32817997-32897824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 4.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 15.6;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 4.5;Spermatogonia: 13.7" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 31.4;BEWO: 94.5;Hep G2: 63.8;NTERA-2: 84.3;SuSa: 76.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: AB_2675857, HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" 0.0 0.0 1.0 0.0 1.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 31.4 0.0 0.0 0.0 94.5 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.6 0.0 63.8 0.0 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.4 0.0 0.0 0.6 6.9 84.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 76.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.8 0.9 0.8 0.1 0.1 0.1 0.0 0.8 0.2 0.0 9.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 2.7 0.0 1.8 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 3.1 0.0 15.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.0 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.6 0.7 0.5 0.0 0.0 0.1 0.3 13.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143342-14532128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 205.7;Excitatory neurons: 400.9;Inhibitory neurons: 443.4;Microglial cells: 308.2;Oligodendrocyte precursor cells: 476.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 215.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: AB_2685315" "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" 35.3 20.5 31.7 11.6 33.3 5.5 31.8 32.2 38.6 23.4 34.5 36.6 6.8 38.9 15.5 14.5 21.2 18.8 31.9 37.2 33.6 24.9 22.1 25.7 10.2 28.1 28.1 52.8 20.6 9.1 28.9 11.6 26.6 28.2 13.6 10.2 17.4 11.1 20.9 18.7 27.8 19.2 26.4 38.9 22.9 17.2 31.4 13.3 17.0 17.4 10.6 27.1 20.5 27.2 43.7 15.9 37.2 18.0 78.6 101.0 41.3 40.4 49.2 32.6 36.9 10.3 17.4 10.4 28.0 56.6 79.6 13.0 6.5 19.4 66.6 25.8 8.0 5.5 46.1 13.2 40.0 13.9 14.8 47.6 19.9 114.4 36.4 30.3 28.8 6.8 1.4 6.8 78.7 8.3 0.1 9.5 9.3 4.8 13.7 9.9 22.9 34.2 31.6 20.5 17.1 67.5 34.3 9.0 18.9 47.1 5.3 2.0 66.4 61.4 38.3 44.7 48.4 0.3 2.2 12.9 215.1 8.8 14.8 0.1 0.5 0.0 0.0 0.7 0.1 0.7 0.0 0.0 0.5 1.8 0.0 0.0 0.0 1.6 0.6 1.1 0.3 0.1 31.7 33.3 32.2 38.6 37.2 33.6 28.1 28.1 26.6 26.4 31.4 27.2 33.0 19.2 25.9 205.7 16.6 16.4 13.0 15.6 17.1 30.5 21.9 15.0 19.3 10.0 21.0 11.0 14.6 9.7 5.6 24.8 0.0 21.2 2.9 11.7 24.8 28.7 18.0 6.5 400.9 14.2 22.0 38.9 7.7 34.2 17.7 17.2 14.6 17.1 14.2 28.6 443.4 20.6 14.2 15.4 22.1 6.6 78.6 20.2 5.4 308.2 12.1 7.3 2.1 476.5 80.4 38.5 14.9 42.9 29.2 52.8 9.2 5.4 18.3 2.7 6.6 27.5 20.0 3.5 6.2 7.2 13.8 8.2 3.8 11.7 19.4 20.3 TRMU "FLJ10140, MTO2, MTU1, TRMT" ENSG00000100416 "TRNA mitochondrial 2-thiouridylase" O75648 22 46330875-46357340 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "RNA-binding, Transferase, tRNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000824, HPA035273, HPA043300" Uncertain Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA000824: AB_2732393, HPA035273: AB_10602901, HPA043300: AB_2678415" "unprognostic (2.96e-1)" "unprognostic (1.09e-2)" "unprognostic (8.07e-2)" "unprognostic (4.27e-2)" "unprognostic (2.64e-1)" "unprognostic (3.52e-3)" "prognostic unfavorable (3.04e-5)" "unprognostic (4.72e-2)" "unprognostic (7.14e-2)" "unprognostic (7.89e-2)" "prognostic favorable (6.86e-4)" "unprognostic (4.74e-3)" "prognostic unfavorable (5.63e-6)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (3.56e-1)" "unprognostic (7.44e-3)" 4.2 7.5 7.7 2.3 7.8 2.9 4.0 8.3 9.6 4.3 8.3 4.5 4.7 3.6 7.5 5.6 3.4 2.6 11.2 7.6 8.5 9.1 8.8 3.5 5.0 8.5 8.6 4.0 10.2 8.0 5.3 4.1 8.5 4.4 4.1 2.8 5.5 4.7 6.9 4.8 4.0 3.9 7.9 4.2 4.3 2.3 8.5 3.0 4.6 8.4 4.3 4.2 4.1 7.8 17.8 16.0 6.6 15.1 12.2 8.6 16.6 18.1 12.6 24.9 19.2 22.7 4.5 11.5 12.5 16.2 10.9 15.3 28.5 16.0 21.1 7.5 38.4 13.6 25.0 27.1 10.4 26.5 9.0 8.2 17.6 25.8 8.1 10.3 16.2 5.8 19.3 2.7 15.3 19.1 10.4 21.5 25.5 10.6 27.5 12.2 14.4 21.2 12.5 12.1 15.9 19.0 16.0 18.5 31.7 8.2 10.7 10.9 11.9 11.1 19.8 15.8 20.7 6.5 7.8 12.6 15.7 19.1 22.8 0.0 6.2 3.8 9.4 9.0 8.3 5.4 8.2 8.9 7.1 5.5 7.3 6.9 1.3 8.0 9.8 5.8 11.0 5.9 7.7 7.8 8.3 9.6 7.6 8.5 8.5 8.6 8.5 7.9 8.5 7.8 12.7 9.6 6.1 22.9 13.2 6.2 10.8 16.8 7.4 26.4 10.6 11.8 14.7 10.0 10.7 11.0 16.7 24.9 16.1 14.1 27.4 20.1 1.6 6.3 10.2 14.5 12.5 14.3 19.4 19.6 21.0 11.9 21.9 6.6 9.5 26.8 13.9 16.8 15.9 13.5 18.0 12.3 10.2 9.9 4.0 3.3 15.2 8.8 8.8 5.6 14.9 11.9 20.6 10.1 14.6 19.5 9.9 17.0 13.8 14.2 15.3 27.9 10.2 26.4 6.6 7.6 14.4 18.5 12.9 9.6 9.7 15.3 13.1 21.0 19.3 9.9 TRNP1 "C1orf225, TRNP" ENSG00000253368 "TMF1 regulated nuclear protein 1" Q6NT89 1 26993692-27000886 "Predicted intracellular proteins" "Cell cycle, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 85.3;retina: 84.3;stomach 1: 124.6" "Group enriched" "Detected in many" 6 "Bipolar cells: 448.0;Gastric mucus-secreting cells: 116.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 208.3;BJ hTERT+: 206.4;EFO-21: 171.4;RPTEC TERT1: 174.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.41e-1)" "unprognostic (7.15e-2)" "unprognostic (7.70e-2)" "unprognostic (1.15e-1)" "unprognostic (2.88e-3)" "unprognostic (6.23e-2)" "prognostic unfavorable (1.90e-6)" "unprognostic (3.53e-1)" "unprognostic (8.39e-3)" "unprognostic (1.64e-1)" "unprognostic (1.90e-1)" "unprognostic (9.71e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.55e-1)" "unprognostic (5.56e-2)" "unprognostic (1.88e-1)" "unprognostic (2.55e-2)" 11.7 5.0 18.7 1.9 20.6 0.0 9.3 19.4 41.8 17.0 2.9 15.8 4.4 17.6 4.1 85.3 16.8 17.5 30.6 23.3 22.9 22.9 4.5 9.6 0.8 30.5 18.6 4.4 21.3 21.6 13.6 7.5 30.3 10.1 2.5 84.3 7.8 10.2 2.4 9.7 6.6 10.4 10.7 5.4 124.6 2.1 29.7 2.1 4.2 1.1 9.7 20.0 18.1 19.2 30.8 88.0 21.1 13.6 162.3 208.3 0.2 153.1 206.4 13.7 6.5 12.1 14.5 0.0 171.4 143.5 5.6 31.0 11.5 62.0 17.0 0.5 8.9 0.1 2.1 63.0 117.3 0.1 0.4 120.3 128.8 7.2 131.0 13.4 13.6 1.0 2.3 0.1 33.7 4.6 0.3 2.3 27.9 136.7 143.7 8.6 0.4 2.4 174.2 9.1 35.5 2.6 29.5 6.3 73.5 13.1 3.0 0.8 71.9 4.6 34.7 73.6 6.7 0.4 0.5 0.6 4.8 0.8 8.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 18.7 20.6 19.4 41.8 23.3 22.9 30.5 18.6 30.3 10.7 29.7 19.2 3.4 19.2 0.6 1.3 0.8 7.4 13.9 1.2 4.6 448.0 6.4 28.4 27.9 32.9 2.4 9.2 8.4 0.2 1.5 0.4 31.3 7.0 0.8 22.2 8.1 2.7 12.0 0.0 7.9 30.9 0.1 3.0 116.7 17.3 0.0 0.4 1.4 1.1 0.2 8.4 11.6 3.5 0.0 3.7 1.1 0.9 9.6 1.7 3.6 1.9 1.3 43.2 0.0 3.0 1.4 25.3 0.1 3.0 0.2 6.6 0.3 0.3 5.6 35.7 26.3 0.8 19.7 1.6 0.8 22.5 8.8 0.0 0.9 0.0 0.3 10.8 TRO "KIAA1114, MAGE-D3, MAGED3" ENSG00000067445 Trophinin Q12816 X 54920462-54931431 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.1" "Cell type enhanced" "Detected in many" "Astrocytes: 9.4;Excitatory neurons: 14.6;Granulosa cells: 12.3;Inhibitory neurons: 20.0;Oligodendrocyte precursor cells: 17.1;Oligodendrocytes: 9.4" "Cancer enhanced" "Detected in many" "testis cancer: 11.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 37.1;SH-SY5Y: 33.8;SuSa: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071449 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "Plasma membrane, Cytosol" "HPA071449: " "unprognostic (6.18e-2)" "unprognostic (1.01e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (9.09e-3)" "unprognostic (2.72e-1)" "unprognostic (5.66e-2)" "unprognostic (1.46e-1)" "unprognostic (4.67e-2)" "unprognostic (3.18e-1)" "prognostic favorable (1.93e-4)" "unprognostic (1.17e-1)" "unprognostic (3.19e-2)" "unprognostic (1.67e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (6.86e-2)" 3.9 3.0 13.9 1.3 10.6 1.0 3.7 0.8 23.7 9.5 0.9 3.2 0.9 13.4 6.6 1.6 5.3 4.2 2.4 9.3 17.2 3.9 16.8 2.1 1.6 6.2 5.1 17.5 7.1 5.3 24.4 4.3 6.9 5.5 2.1 6.2 1.5 5.2 31.1 1.2 1.6 8.6 3.4 1.0 2.0 2.6 12.6 4.7 10.1 1.0 1.6 2.5 5.5 13.3 0.0 0.3 37.1 0.1 7.1 9.8 0.0 2.1 13.1 2.0 0.7 0.0 0.0 0.0 5.3 13.8 3.1 0.2 0.3 0.6 1.0 0.1 23.3 18.0 0.0 1.5 2.7 0.0 0.1 22.8 0.0 12.0 0.0 11.8 0.9 9.1 0.0 0.2 14.0 0.0 0.3 0.1 19.6 0.1 0.0 11.3 16.4 0.1 3.5 0.3 25.3 33.8 0.0 0.5 3.1 74.2 0.0 2.2 0.0 15.7 15.9 0.2 2.2 5.8 0.9 0.0 2.3 0.0 13.8 0.0 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 2.2 0.1 0.9 0.0 0.1 13.9 10.6 0.8 23.7 9.3 17.2 6.2 5.1 6.9 3.4 12.6 13.3 0.4 0.0 0.0 9.4 0.3 0.4 1.4 0.8 5.2 4.2 0.5 1.9 1.8 0.0 1.9 3.7 0.0 0.8 0.2 0.0 0.0 1.7 0.4 0.3 7.9 1.9 0.0 0.0 14.6 0.2 0.6 7.0 0.5 0.5 1.3 12.3 0.4 0.0 0.5 8.4 20.0 0.0 0.0 0.0 0.4 0.6 5.9 0.2 0.0 1.0 0.1 2.2 0.0 17.1 9.4 0.2 0.0 3.8 0.1 0.4 0.0 0.4 0.0 0.9 0.0 1.5 3.3 1.2 1.9 0.1 0.1 0.7 0.7 2.9 0.0 0.3 TRUB1 PUS4 ENSG00000165832 "TruB pseudouridine synthase family member 1" Q8WWH5 10 114938195-114977676 "Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 62.2;Theca cells: 74.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037914, HPA057552" Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA037914: AB_10672399, HPA057552: AB_2683465" "unprognostic (1.98e-1)" "unprognostic (1.91e-2)" "unprognostic (1.27e-2)" "unprognostic (2.93e-2)" "unprognostic (3.20e-3)" "unprognostic (9.79e-2)" "unprognostic (9.26e-2)" "unprognostic (4.89e-2)" "unprognostic (6.87e-2)" "unprognostic (2.51e-2)" "unprognostic (2.26e-2)" "unprognostic (1.56e-1)" "unprognostic (1.50e-3)" "unprognostic (7.54e-2)" "unprognostic (2.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.09e-1)" 7.4 29.3 6.3 7.5 7.4 4.2 11.3 5.1 9.0 9.8 7.3 9.5 8.9 12.8 9.3 8.3 9.7 7.7 21.5 7.6 7.1 16.0 12.9 6.6 10.0 5.8 6.0 16.8 6.8 15.8 4.9 7.5 6.1 11.7 10.4 6.7 9.3 9.9 7.5 6.5 8.2 11.1 5.6 9.3 8.7 17.9 7.0 11.5 12.3 9.7 10.1 7.8 4.8 6.4 25.5 19.6 18.8 47.0 13.3 17.7 25.3 21.4 24.1 28.4 32.0 16.1 25.5 31.4 24.2 16.9 12.4 21.3 25.6 26.5 41.8 23.9 27.5 14.4 9.2 28.8 22.8 27.2 20.7 18.2 35.8 20.2 39.6 30.1 16.2 24.9 15.1 12.5 34.1 12.3 25.7 21.6 17.8 17.0 19.1 25.4 47.5 19.2 37.4 12.7 17.5 19.3 18.0 26.4 47.7 20.0 21.1 16.6 14.5 13.0 13.0 20.8 26.5 23.6 20.4 26.3 18.3 34.2 11.9 4.0 2.6 0.9 4.4 4.0 6.5 7.3 4.7 4.7 4.8 5.9 6.2 5.8 0.2 8.1 7.3 4.3 6.2 4.6 6.3 7.4 5.1 9.0 7.6 7.1 5.8 6.0 6.1 5.6 7.0 6.4 6.9 12.8 8.4 8.8 11.2 5.6 4.7 15.3 6.2 13.9 11.9 8.1 13.6 4.3 12.0 9.2 2.1 9.1 10.5 7.1 21.5 7.6 62.2 11.1 12.8 6.6 7.7 9.0 23.0 4.9 6.6 11.2 6.6 12.0 10.2 26.7 12.1 20.2 7.6 25.2 22.0 8.2 6.1 7.3 4.2 9.6 8.4 5.0 3.6 8.4 5.4 10.4 9.2 31.2 16.7 7.0 3.6 10.1 12.7 4.2 6.2 27.9 9.8 5.6 6.6 8.4 9.3 14.5 23.3 15.9 7.0 6.2 8.0 74.1 12.9 5.8 TSC2 "LAM, PPP1R160, TSC4, tuberin" ENSG00000103197 "TSC complex subunit 2" P49815 16 2047967-2089491 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002225, HPA030409, HPA049679" Approved Enhanced Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Cytosol "CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848" "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (2.04e-2)" "unprognostic (6.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.94e-2)" "prognostic favorable (5.06e-4)" "unprognostic (4.32e-2)" "unprognostic (3.91e-2)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-2)" "unprognostic (8.96e-2)" 12.6 10.0 3.8 10.2 4.6 10.9 12.6 4.5 6.1 16.7 0.9 15.3 12.4 17.4 7.3 12.0 16.0 10.9 12.6 5.9 1.3 9.6 9.0 12.0 7.7 3.1 1.5 18.4 14.8 14.7 16.5 9.2 2.7 12.4 9.1 17.7 21.3 15.6 31.1 14.4 12.8 11.4 0.1 11.4 15.7 16.2 2.6 11.7 18.6 14.5 7.8 14.0 12.8 12.5 13.5 21.4 28.9 32.5 33.7 28.1 24.3 31.7 21.7 23.4 19.7 25.7 25.4 20.5 27.6 26.2 11.0 22.0 17.5 23.1 17.3 15.5 28.5 19.2 39.6 10.7 23.0 24.0 22.4 33.5 14.3 18.9 13.9 27.9 22.3 14.4 19.0 17.7 21.0 27.0 28.9 7.1 29.8 10.1 21.2 45.3 31.6 25.7 9.4 12.1 22.1 41.3 45.2 29.4 15.3 28.2 26.8 17.5 35.5 24.5 16.5 22.0 16.5 39.0 42.7 40.8 10.2 9.7 29.6 3.2 2.7 2.8 3.1 2.1 2.8 1.8 1.9 1.7 2.5 1.8 1.3 2.1 3.5 1.6 1.7 0.6 1.4 2.2 3.8 4.6 4.5 6.1 5.9 1.3 3.1 1.5 2.7 0.1 2.6 12.5 23.8 25.6 18.9 43.8 16.8 9.2 8.1 10.1 14.8 53.8 23.7 20.2 41.8 21.5 15.3 20.2 93.8 13.0 17.3 34.5 3.9 15.2 13.1 47.8 26.3 25.6 32.5 17.4 22.8 14.1 8.0 19.7 44.9 62.1 8.8 49.0 32.2 38.7 11.4 45.4 22.4 26.6 8.2 17.6 9.9 29.3 28.3 13.8 8.8 15.9 12.1 19.0 36.0 18.6 25.7 21.4 17.5 25.9 14.4 9.4 25.4 8.9 17.8 64.7 13.1 17.2 20.4 18.3 37.7 12.9 9.8 9.3 18.8 31.6 28.9 10.6 TSC22D1 "MGC17597, TGFB1I4, TSC22" ENSG00000102804 "TSC22 domain family member 1" Q15714 13 44432143-44577147 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1231.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 44.7" "Group enriched" "Detected in all" 5 "dendritic cells: 17.9;granulocytes: 44.7;NK-cells: 16.7" "Cell line enhanced" "Detected in many" "HEL: 247.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077414 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Nuclear bodies" "HPA077414: AB_2686839" "unprognostic (6.61e-2)" "unprognostic (1.66e-1)" "unprognostic (4.00e-1)" "unprognostic (6.40e-2)" "unprognostic (5.22e-2)" "unprognostic (4.78e-3)" "unprognostic (6.30e-2)" "unprognostic (2.04e-1)" "unprognostic (2.56e-1)" "prognostic unfavorable (7.97e-4)" "unprognostic (4.24e-2)" "unprognostic (9.08e-2)" "prognostic favorable (4.54e-4)" "unprognostic (8.14e-2)" "unprognostic (6.52e-2)" "unprognostic (1.83e-2)" "unprognostic (4.48e-2)" 125.9 88.8 261.8 58.9 276.9 16.5 143.1 223.1 295.7 162.3 283.4 133.0 64.9 159.4 138.5 107.6 152.0 115.6 128.2 272.4 252.1 172.1 86.9 120.3 38.6 248.0 270.8 180.1 35.4 114.1 110.3 88.0 253.9 181.5 109.1 73.7 76.1 84.7 190.8 67.6 118.2 147.6 237.8 26.7 115.0 61.8 268.6 168.6 88.3 125.7 41.4 138.1 87.3 245.4 21.7 67.7 62.1 24.6 36.3 45.7 75.5 22.4 93.9 23.1 25.8 77.1 74.9 35.4 48.6 47.9 52.6 53.8 25.1 191.2 33.4 6.5 22.2 247.3 116.9 23.4 36.1 12.8 30.1 65.0 80.2 65.6 162.0 184.8 55.6 18.6 6.9 0.2 45.5 21.0 44.9 10.3 45.3 148.8 61.6 31.1 11.6 10.6 47.7 35.5 33.5 45.3 64.3 61.8 18.6 65.1 30.8 19.5 49.6 26.4 25.8 59.1 34.9 0.6 6.6 10.2 70.0 10.6 65.7 44.7 1.9 5.8 4.6 1.9 4.4 1.3 1.4 2.1 1.8 2.0 1.5 2.2 8.6 16.7 5.1 17.9 3.4 50.0 261.8 276.9 223.1 295.7 272.4 252.1 248.0 270.8 253.9 237.8 268.6 245.4 739.9 118.6 368.2 77.7 21.4 441.9 415.0 905.0 870.2 147.8 464.9 296.5 279.9 97.2 425.3 435.9 114.7 584.7 34.9 660.8 369.8 190.8 851.5 186.0 105.0 643.0 225.0 118.9 302.4 157.0 177.2 234.3 211.0 313.8 314.2 108.2 88.9 74.5 106.5 127.9 261.0 254.0 526.9 21.1 153.3 1231.0 91.6 218.4 402.0 148.0 16.2 246.2 26.8 207.1 103.8 229.5 339.6 136.5 17.2 550.9 212.0 155.1 265.8 149.9 447.0 268.2 500.9 80.9 34.6 178.2 610.0 1170.1 65.0 80.6 273.6 445.8 TSC22D2 "KIAA0669, TILZ4a, TILZ4b, TILZ4c" ENSG00000196428 "TSC22 domain family member 2" O75157 3 150408335-150466431 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004926 Approved Approved Cytosol NA NA 100000 "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA004926: AB_1080401" "unprognostic (4.65e-2)" "unprognostic (1.54e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (2.49e-1)" "unprognostic (2.65e-2)" "unprognostic (1.89e-1)" "unprognostic (1.09e-2)" "unprognostic (7.63e-2)" "unprognostic (2.59e-1)" "unprognostic (2.28e-3)" "unprognostic (8.32e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (1.10e-2)" "unprognostic (4.86e-1)" "unprognostic (1.10e-2)" "unprognostic (3.49e-1)" 20.9 11.8 8.1 10.7 8.9 34.9 13.2 9.9 15.2 18.9 3.3 14.9 6.0 23.4 14.4 23.8 15.4 22.6 21.5 9.1 9.0 15.9 29.6 15.0 10.3 8.5 8.8 15.2 11.4 10.8 9.8 16.9 9.0 11.4 12.4 16.7 10.6 7.3 17.0 11.1 11.9 26.3 6.1 13.8 16.3 17.8 6.6 11.8 12.9 14.4 9.9 20.6 23.3 11.1 45.7 6.2 19.6 18.8 25.1 12.2 56.4 44.6 16.9 32.1 39.5 25.0 22.4 14.9 25.1 33.7 65.7 18.9 19.8 16.2 63.7 11.8 11.1 16.0 11.6 12.7 28.5 9.8 10.6 22.6 12.4 20.9 31.4 19.4 20.4 7.1 27.7 23.9 22.6 16.1 10.5 12.1 25.1 13.6 12.3 11.0 35.8 17.7 20.7 26.6 11.3 10.1 20.5 10.8 45.8 23.5 10.3 13.0 33.0 21.1 21.9 25.3 41.6 31.9 6.6 20.6 14.3 29.2 12.7 0.5 1.7 2.0 1.1 1.6 1.8 1.1 1.4 1.2 1.1 1.4 1.1 1.1 2.2 2.0 2.9 1.2 0.6 1.5 8.1 8.9 9.9 15.2 9.1 9.0 8.5 8.8 9.0 6.1 6.6 11.1 97.4 64.1 30.8 160.3 52.5 148.9 81.5 12.6 111.0 18.6 65.1 28.4 46.9 20.0 18.2 12.9 29.2 28.6 53.7 77.6 17.6 13.8 23.2 85.5 107.6 48.3 31.6 10.3 78.7 13.8 33.0 59.6 50.0 166.6 65.4 10.9 29.3 40.1 18.4 16.8 70.9 45.4 22.4 24.1 94.9 29.6 18.6 58.9 42.7 86.2 20.2 31.8 16.5 59.3 86.5 26.0 82.2 15.1 37.3 42.6 16.0 10.6 10.8 21.3 13.1 79.0 48.9 51.6 29.3 77.0 108.3 54.9 48.7 17.9 34.8 83.5 TSC22D3 "DIP, DSIPI, GILZ, hDIP, TSC-22R" ENSG00000157514 "TSC22 domain family member 3" Q99576 X 107713221-107777342 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 1234.8;dendritic cells: 1146.4;Plasma cells: 2348.5;T-cells: 1479.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 380.5;ASC TERT1: 259.7;HHSteC: 628.0;hTCEpi: 572.7;Karpas-707: 364.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001916, CAB034364" Approved Approved "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Nuclear speckles, Golgi apparatus" "CAB034364: AB_2272198, HPA001916: AB_2666504" "unprognostic (3.67e-2)" "unprognostic (3.90e-3)" "unprognostic (5.99e-2)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.49e-2)" "unprognostic (3.21e-2)" "unprognostic (3.73e-3)" "unprognostic (4.40e-2)" "unprognostic (9.42e-2)" "unprognostic (5.32e-2)" "unprognostic (3.25e-1)" "unprognostic (7.47e-2)" "unprognostic (6.38e-2)" "unprognostic (1.37e-3)" "unprognostic (6.41e-2)" "unprognostic (4.14e-1)" "unprognostic (9.64e-2)" 536.4 240.5 90.3 394.8 93.5 433.3 447.3 101.0 105.0 396.4 104.1 290.2 87.2 269.3 72.0 300.4 369.8 167.1 331.9 81.3 102.9 194.9 177.4 522.6 281.0 99.6 97.2 371.1 113.8 55.7 136.2 163.8 98.9 404.4 183.6 22.5 333.4 160.5 729.3 493.6 426.3 178.7 92.8 408.2 390.4 43.8 99.3 203.2 313.0 187.8 338.2 508.2 486.9 91.3 10.9 18.2 9.3 25.7 380.5 259.7 3.7 16.9 14.1 7.8 8.6 0.1 35.8 23.4 40.1 13.7 5.5 53.5 19.1 54.2 3.3 7.0 9.0 11.5 76.9 1.0 628.0 2.5 37.7 238.8 572.7 6.1 158.7 78.8 29.3 2.5 3.6 364.1 67.2 37.8 0.7 40.5 16.3 11.5 11.7 1.2 23.5 51.3 26.1 7.3 2.4 20.3 16.6 89.2 128.8 16.9 17.0 52.4 44.1 23.6 7.1 4.8 3.4 79.6 37.8 11.2 12.0 46.7 6.7 668.9 417.2 1653.1 649.7 524.1 484.2 584.0 740.6 641.5 399.5 559.6 686.3 643.0 2396.6 968.4 851.8 81.4 1080.9 1624.1 90.3 93.5 101.0 105.0 81.3 102.9 99.6 97.2 98.9 92.8 99.3 91.3 423.5 64.1 164.7 10.4 1234.8 110.0 82.8 129.7 435.4 52.0 97.0 47.5 31.8 70.1 106.9 47.8 0.0 3.2 1146.4 26.2 232.8 28.3 28.8 24.2 40.9 171.7 64.2 481.5 13.1 22.2 140.5 454.2 200.3 29.7 353.2 15.3 247.0 95.6 121.3 62.2 12.9 32.9 83.4 396.3 191.8 41.2 230.5 539.1 437.6 16.9 126.0 8.9 234.8 37.7 23.7 22.7 19.6 319.7 2348.5 106.5 58.6 48.6 61.0 19.1 433.9 245.4 248.3 24.1 15.3 182.6 79.1 9.9 1479.6 89.6 33.0 42.2 TSC22D4 "THG-1, TILZ2" ENSG00000166925 "TSC22 domain family member 4" Q9Y3Q8 7 100463359-100479232 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 601.0;choroid plexus: 224.0" "Cell type enriched" "Detected in all" 4 "Muller glia cells: 778.8" "Cancer enhanced" "Detected in all" "glioma: 118.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 198.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006757 Uncertain Approved Cytosol NA NA 160000 "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 24: NB-4 - Immune response" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA006757: AB_1080403" "unprognostic (2.34e-2)" "unprognostic (3.06e-2)" "prognostic unfavorable (2.66e-4)" "unprognostic (5.77e-2)" "unprognostic (1.69e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (9.45e-4)" "unprognostic (9.96e-2)" "unprognostic (1.27e-1)" "unprognostic (1.62e-2)" "unprognostic (2.31e-2)" "unprognostic (3.36e-1)" "unprognostic (1.09e-1)" "unprognostic (1.54e-2)" "unprognostic (3.84e-2)" "unprognostic (7.36e-2)" "unprognostic (3.81e-3)" 37.1 52.7 437.1 33.6 601.0 72.0 36.1 524.6 456.9 43.4 224.0 47.5 23.5 40.5 10.1 73.0 36.8 14.4 59.7 384.9 457.3 64.1 30.0 42.6 40.6 527.5 563.9 44.1 37.3 18.5 52.1 22.7 484.3 55.7 10.7 21.9 97.6 22.2 26.2 58.8 44.4 14.0 485.2 95.2 38.6 36.7 538.9 31.2 34.5 28.7 23.2 37.8 46.8 565.4 42.0 30.8 10.3 33.7 34.2 40.5 19.9 30.5 49.6 28.3 25.8 16.9 25.0 36.8 36.1 24.4 66.0 31.2 12.2 26.7 9.9 65.6 25.2 34.2 34.5 14.6 54.4 44.1 86.3 45.7 24.0 32.4 32.2 33.0 58.3 29.0 75.2 64.2 22.9 74.3 55.6 198.4 14.0 35.7 42.6 89.7 8.1 51.6 23.2 22.3 8.8 25.1 41.4 78.8 65.5 16.7 22.5 63.1 50.2 38.4 39.1 95.0 22.8 40.9 42.6 27.1 35.7 66.4 47.8 9.7 18.7 30.0 19.0 20.2 14.9 11.9 16.3 17.9 12.7 11.8 15.2 16.2 56.1 18.8 20.5 13.3 25.0 18.2 437.1 601.0 524.6 456.9 384.9 457.3 527.5 563.9 484.3 485.2 538.9 565.4 16.7 12.8 8.9 123.4 50.8 32.8 35.9 50.7 37.5 15.4 47.3 61.3 17.7 44.3 32.5 40.5 6.2 30.7 69.3 60.3 137.0 63.5 1.7 14.0 25.5 26.1 33.6 60.6 3.8 33.9 35.3 29.8 21.4 19.9 15.9 36.1 42.1 11.1 79.9 18.5 4.6 32.1 38.7 57.7 67.1 5.2 45.7 56.7 55.2 14.0 77.2 778.8 116.4 50.8 162.6 60.6 52.7 39.9 31.8 59.2 62.8 21.0 13.7 18.2 46.0 16.1 34.5 1.7 5.4 32.8 33.8 79.1 78.2 28.9 31.7 80.3 TSFM "EF-TS, EF-Tsmt" ENSG00000123297 "Ts translation elongation factor, mitochondrial" P43897 12 57782761-57808071 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 6 "RH-30: 962.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006204 Supported Nucleoplasm,Mitochondria NA NA 9200 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA006204: AB_1080405" "unprognostic (1.17e-1)" "unprognostic (6.84e-3)" "unprognostic (1.93e-2)" "unprognostic (6.87e-2)" "unprognostic (1.87e-1)" "unprognostic (2.56e-3)" "unprognostic (2.49e-2)" "unprognostic (1.53e-1)" "unprognostic (8.52e-2)" "unprognostic (1.80e-1)" "unprognostic (1.49e-1)" "unprognostic (1.49e-3)" "prognostic favorable (8.82e-4)" "unprognostic (3.05e-1)" "unprognostic (6.97e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" 23.1 57.6 17.7 23.5 18.5 26.1 26.3 18.8 20.9 16.7 21.1 28.9 27.4 15.0 17.4 22.3 18.0 13.9 43.6 18.8 19.0 39.2 45.2 15.1 24.2 18.4 18.3 13.5 17.1 35.0 16.5 16.5 19.7 16.6 26.8 16.7 20.0 16.4 58.6 21.6 21.0 17.5 19.0 17.4 19.7 25.2 18.9 22.5 16.2 64.3 20.7 24.4 15.7 18.7 56.3 63.1 35.5 52.5 33.7 33.9 53.2 46.4 39.8 71.6 50.2 74.1 71.6 142.6 85.8 38.9 39.1 64.9 60.1 66.2 51.3 57.7 78.0 82.6 51.9 64.7 50.5 112.7 47.2 39.6 65.3 55.6 25.4 52.2 44.7 75.7 110.3 70.0 56.3 64.8 64.8 113.0 57.5 81.7 83.7 78.3 962.0 125.5 70.5 64.1 80.0 49.1 47.7 84.8 83.6 31.5 148.9 71.7 33.1 39.6 54.6 58.9 49.1 52.0 120.2 108.7 53.6 63.7 48.1 8.5 24.6 15.3 28.0 23.7 36.0 28.5 30.9 28.3 30.3 26.9 31.1 31.7 6.5 33.6 30.5 23.4 30.9 26.9 17.7 18.5 18.8 20.9 18.8 19.0 18.4 18.3 19.7 19.0 18.9 18.7 16.5 19.2 10.8 6.2 18.5 25.9 14.5 57.4 10.8 19.4 24.6 21.1 31.8 27.1 28.7 46.0 14.6 68.5 23.5 13.2 95.9 66.0 73.3 19.5 19.7 18.7 13.8 20.0 8.4 87.6 52.3 18.8 13.3 16.3 22.2 31.0 16.4 38.3 35.4 15.2 8.5 20.9 36.7 11.4 13.9 42.5 22.7 18.1 26.6 10.3 66.6 23.1 12.3 9.5 8.4 47.2 15.7 24.0 17.5 21.3 19.9 146.2 26.0 20.1 59.2 19.7 31.6 46.1 65.8 21.1 36.2 47.6 18.6 71.1 35.3 13.9 TSGA10IP "FAM161C, FLJ32880" ENSG00000175513 "Testis specific 10 interacting protein" Q3SY00 11 65945445-65959963 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "testis: 10.0" "Group enriched" "Detected in some" 5 "Early spermatids: 54.6;Late spermatids: 59.8" "Group enriched" "Detected in some" 7 "testis cancer: 1.5;thyroid cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.69e-1)" "unprognostic (8.39e-3)" "unprognostic (3.84e-1)" "unprognostic (6.76e-2)" "unprognostic (2.31e-1)" "unprognostic (3.57e-4)" "unprognostic (8.66e-2)" "unprognostic (8.53e-3)" "unprognostic (1.69e-1)" "unprognostic (1.11e-1)" "unprognostic (5.47e-2)" "unprognostic (5.61e-1)" "unprognostic (1.62e-4)" "unprognostic (8.96e-2)" "unprognostic (2.31e-1)" "unprognostic (7.35e-2)" "unprognostic (6.66e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 10.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.6 0.0 59.8 0.9 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TSHB ENSG00000134200 "Thyroid stimulating hormone subunit beta" P01222 1 115029826-115034302 "Human disease related genes, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2634 "pituitary gland: 1757.6" "Cell type enhanced" "Detected in single" "Late spermatids: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Not detected" "Not detected" "CAB022202, HPA042681" Enhanced "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 25: Spermatids - Spermatogenesis" "CAB022202: , HPA042681: AB_2732500" "unprognostic (2.14e-4)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" 0.1 0.6 0.3 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.3 0.1 0.0 0.2 0.1 0.4 0.2 0.0 0.4 0.3 0.0 0.3 0.0 1757.6 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.2 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.2 0.4 0.3 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSHR LGR3 ENSG00000165409 "Thyroid stimulating hormone receptor" P16473 14 80954989-81146306 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "thyroid gland: 273.9" "Group enriched" "Detected in some" 4 "Astrocytes: 5.5;Excitatory neurons: 7.0;Inhibitory neurons: 12.3;Microglial cells: 6.5;Oligodendrocyte precursor cells: 6.6;Oligodendrocytes: 9.5;Plasma cells: 11.7;Skeletal myocytes: 4.1" "Cancer enriched" "Detected in some" 116 "thyroid cancer: 100.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "naive B-cell: 1.7;T-reg: 6.9" "Group enriched" "Detected in many" 5 "B-cells: 1.7;T-cells: 6.9" "Cell line enhanced" "Detected in some" "JURKAT: 58.4;MOLT-4: 23.8;SCLC-21H: 23.0;U-266/70: 11.3" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "hypothalamus: 1.3" CAB000473 Approved "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 1: Thyroid gland - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB000473: AB_2303782" "unprognostic (3.36e-3)" "unprognostic (1.31e-3)" "unprognostic (1.02e-2)" "unprognostic (4.17e-6)" "unprognostic (3.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.83e-1)" "unprognostic (2.66e-2)" "unprognostic (3.39e-2)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" "unprognostic (7.11e-3)" "unprognostic (5.08e-7)" "unprognostic (1.32e-1)" "unprognostic (7.40e-2)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" 0.5 0.6 1.6 0.8 1.8 1.2 0.8 4.0 2.3 0.2 0.2 0.5 0.3 0.6 0.5 0.2 0.8 0.5 0.3 1.3 0.5 0.3 0.4 0.2 1.9 0.8 0.3 0.3 0.4 0.3 0.2 0.4 0.5 0.5 0.3 2.3 0.6 0.2 0.8 1.1 0.4 0.2 0.1 0.8 0.5 0.7 1.2 20.8 273.9 0.2 0.8 0.3 0.1 1.8 0.4 0.2 0.7 0.4 0.1 0.1 0.3 0.2 0.0 0.0 0.1 0.4 0.5 0.7 0.2 0.1 0.5 0.3 0.3 0.0 0.1 0.3 0.1 0.3 0.8 0.4 0.0 0.2 0.4 0.3 0.1 0.1 0.3 0.1 0.0 58.4 0.3 0.7 0.1 0.4 23.8 0.5 0.4 0.1 0.2 0.8 0.2 0.9 0.0 0.5 23.0 0.4 0.2 0.2 0.3 0.5 0.3 0.1 0.2 0.7 0.5 0.6 0.3 11.3 6.3 0.6 0.3 0.3 0.5 0.5 0.1 0.1 0.1 0.1 0.1 0.6 0.5 0.3 0.1 1.7 0.2 0.1 0.9 0.1 0.2 0.5 6.9 0.1 1.6 1.8 4.0 2.3 1.3 0.5 0.8 0.3 0.5 0.1 1.2 1.8 0.2 0.0 0.5 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.8 0.0 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.1 0.2 0.3 1.8 0.0 7.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.3 0.2 0.0 0.0 0.0 1.1 0.0 0.1 0.0 6.5 0.0 0.1 0.0 6.6 9.5 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.6 0.0 4.1 1.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 TSKU "E2IG4, LRRC54, TSK" ENSG00000182704 "Tsukushi, small leucine rich proteoglycan" Q8WUA8 11 76782251-76798153 "Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 237.3" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 506.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 168.0;ASC diff: 282.5;OE19: 188.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008164 Approved Approved "Nucleoplasm,Nuclear bodies" "Secreted to blood" NA NA 6200000 "Cluster 6: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "Nuclear bodies" "HPA008164: AB_1853327" "unprognostic (1.07e-2)" "unprognostic (2.29e-3)" "unprognostic (6.15e-2)" "prognostic favorable (3.66e-4)" "unprognostic (7.05e-2)" "unprognostic (2.39e-1)" "unprognostic (3.08e-1)" "unprognostic (2.17e-3)" "unprognostic (4.81e-2)" "unprognostic (4.62e-2)" "prognostic unfavorable (2.87e-4)" "prognostic favorable (1.66e-4)" "prognostic unfavorable (2.80e-8)" "unprognostic (1.47e-1)" "unprognostic (4.93e-2)" "unprognostic (6.71e-2)" "unprognostic (3.88e-2)" 96.5 12.1 4.2 8.3 4.5 2.1 80.4 6.5 5.8 147.1 27.8 23.5 37.1 46.4 20.6 62.8 67.7 14.9 34.8 6.5 2.7 41.5 237.3 15.0 2.4 4.4 3.1 47.0 16.8 6.4 14.8 30.3 5.0 44.0 14.4 4.1 33.9 24.6 9.5 60.0 32.3 41.1 1.9 6.9 28.2 9.1 3.9 4.7 37.6 5.7 5.6 41.6 99.6 4.4 3.7 168.0 19.1 18.4 282.5 36.1 34.6 5.9 32.2 12.6 12.0 22.2 48.0 0.3 32.7 21.1 53.7 68.6 10.9 42.7 3.9 35.7 5.9 8.3 43.5 63.1 53.6 3.0 11.9 37.3 46.0 22.5 18.2 24.0 15.7 6.4 19.9 1.4 11.7 81.9 0.5 6.5 24.5 188.9 7.4 5.9 18.3 28.7 29.7 29.7 16.8 28.5 32.7 25.7 15.4 15.8 34.5 2.7 4.9 35.4 28.2 86.8 14.2 1.1 0.6 1.4 16.6 8.9 6.4 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.0 4.2 4.5 6.5 5.8 6.5 2.7 4.4 3.1 5.0 1.9 3.9 4.4 6.2 0.0 0.5 1.0 0.5 17.3 12.1 25.8 27.9 3.5 13.6 13.2 3.2 11.5 12.1 1.8 0.0 50.0 0.1 33.2 0.0 6.7 0.2 8.1 35.6 5.8 7.8 13.5 0.5 21.7 71.8 33.0 14.8 10.6 1.3 38.7 9.7 506.3 9.9 0.0 0.1 12.4 26.4 9.1 6.4 2.0 37.3 0.8 5.4 1.9 1.6 9.2 0.0 0.0 0.0 21.3 21.2 45.1 0.1 14.6 28.6 21.9 3.0 0.6 0.0 1.0 11.3 0.4 2.0 22.3 22.6 43.8 1.6 8.6 13.8 20.1 TSLP ENSG00000145777 "Thymic stromal lymphopoietin" Q969D9 5 111070062-111078026 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 11.5;urinary bladder: 12.0" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 108.1;Basal squamous epithelial cells: 338.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 15.0;HHSteC: 17.1;hTCEpi: 10.3;hTEC/SVTERT24-B: 18.9;hTERT-HME1: 12.5;hTERT-RPE1: 38.6;U-87 MG: 14.1" "Not detected" "Not detected" HPA056350 Uncertain "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 38400 "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "HPA056350: " "unprognostic (6.47e-4)" "unprognostic (3.26e-1)" "unprognostic (6.57e-2)" "unprognostic (1.93e-1)" "unprognostic (5.03e-2)" "unprognostic (7.72e-2)" "unprognostic (1.21e-1)" "unprognostic (2.53e-2)" "unprognostic (5.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-1)" "unprognostic (1.88e-1)" "unprognostic (5.04e-2)" "unprognostic (1.95e-1)" "unprognostic (2.76e-1)" "unprognostic (1.74e-3)" 1.6 0.7 0.3 1.3 0.3 0.0 1.5 0.3 0.5 1.4 0.2 1.1 0.7 0.8 0.3 3.8 0.6 8.8 4.3 0.3 0.3 1.2 11.5 1.9 0.4 0.4 0.3 0.3 0.3 0.4 0.4 0.1 0.4 6.2 0.9 0.0 1.2 4.0 1.4 0.8 1.0 0.6 0.3 0.4 1.2 4.8 1.1 0.2 2.7 1.4 0.5 12.0 1.9 0.4 0.0 0.0 0.0 1.8 2.3 15.0 0.0 0.0 2.3 0.4 2.6 0.0 0.0 0.0 0.1 0.0 0.5 0.0 1.5 0.5 0.8 0.0 2.4 2.8 0.1 0.0 17.1 0.5 0.0 0.3 10.3 18.9 12.5 38.6 0.0 6.6 0.3 0.0 3.2 0.0 2.5 0.0 0.4 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.1 2.2 0.0 0.0 0.0 1.2 0.0 1.1 0.0 0.0 0.9 0.0 0.0 4.1 0.0 0.0 14.1 0.3 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.3 0.3 0.4 0.3 0.4 0.3 1.1 0.4 6.2 0.0 3.1 0.3 0.1 55.8 26.6 108.1 338.6 0.0 6.5 8.0 7.4 0.0 35.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 38.5 0.1 0.9 10.5 0.0 0.0 0.0 0.0 0.1 10.0 0.0 0.1 0.0 0.9 7.9 9.4 0.2 0.0 0.0 0.0 24.4 1.2 5.0 26.3 0.6 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 24.7 0.2 1.6 3.5 0.0 0.0 6.9 3.8 0.4 0.9 38.0 25.1 0.0 0.8 1.9 0.1 3.1 TSPAN3 "TM4-A, TM4SF8, TSPAN-3" ENSG00000140391 "Tetraspanin 3" O60637 15 77041404-77083984 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 705.9;Muller glia cells: 508.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "memory B-cell: 481.0;naive B-cell: 488.1;plasmacytoid DC: 313.2" "Group enriched" "Detected in all" 5 "B-cells: 488.1;dendritic cells: 313.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015996 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA015996: AB_1858406" "unprognostic (5.94e-2)" "unprognostic (3.05e-1)" "unprognostic (7.32e-2)" "unprognostic (2.15e-2)" "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (1.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (5.41e-3)" "unprognostic (3.51e-3)" "unprognostic (2.90e-2)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-1)" "unprognostic (3.79e-3)" "unprognostic (1.35e-1)" 333.8 143.9 257.2 87.3 248.9 33.3 143.3 253.4 292.4 138.2 288.7 364.2 342.1 130.9 432.8 78.4 249.8 186.2 108.8 247.8 296.3 211.3 87.4 202.1 88.0 250.0 267.7 148.1 140.2 283.4 189.7 111.6 260.2 96.2 386.3 418.6 152.2 187.3 429.1 78.3 349.2 128.3 266.7 84.8 221.2 84.8 282.5 71.6 200.3 374.4 106.9 170.1 67.4 281.3 130.6 347.6 282.8 179.3 484.7 295.8 93.3 203.7 220.2 245.1 265.7 213.5 264.7 126.9 294.8 211.6 234.0 289.0 271.2 139.5 182.9 143.4 410.4 91.0 252.5 204.4 234.5 118.4 64.3 280.9 165.5 135.8 120.1 372.6 304.8 83.1 98.0 109.2 243.3 49.5 105.7 112.1 200.5 414.7 152.4 130.8 351.0 135.3 408.0 73.0 255.0 282.1 139.8 116.9 393.7 269.3 125.0 220.8 292.1 225.7 88.4 138.0 290.7 237.4 346.6 67.1 200.1 173.5 131.9 8.8 51.3 10.4 32.6 69.6 34.1 481.0 16.5 23.9 99.2 488.1 42.6 39.3 4.8 60.3 77.1 313.2 4.6 95.2 257.2 248.9 253.4 292.4 247.8 296.3 250.0 267.7 260.2 266.7 282.5 281.3 76.1 112.2 213.4 69.5 83.8 34.7 77.5 114.6 36.5 247.7 43.6 32.3 98.2 108.7 169.0 68.0 183.5 89.9 41.3 705.9 25.4 250.2 28.5 86.1 63.4 57.6 91.3 19.4 47.8 354.0 35.6 90.8 85.1 41.7 23.4 88.6 53.6 29.5 65.4 127.9 54.3 290.4 97.6 58.0 27.5 57.9 64.3 38.2 72.9 29.0 35.1 508.9 36.0 116.6 32.7 245.1 410.7 51.6 81.2 220.1 364.3 65.5 201.7 185.1 26.3 44.8 189.0 108.0 64.6 34.2 34.2 75.9 19.4 149.5 205.2 381.4 TSPAN31 SAS ENSG00000135452 "Tetraspanin 31" Q12999 12 57738013-57750219 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "glioma: 54.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030758, HPA057489" Approved Approved "Nucleoplasm,Golgi apparatus,Cytokinetic bridge,Cytosol" Yes No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA030758: , HPA057489: AB_2683447" "unprognostic (2.66e-2)" "unprognostic (1.50e-1)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (8.96e-3)" "prognostic unfavorable (1.09e-4)" "unprognostic (4.31e-3)" "unprognostic (1.19e-1)" "unprognostic (6.51e-3)" "unprognostic (5.31e-2)" "unprognostic (2.68e-1)" "unprognostic (2.79e-1)" "prognostic favorable (9.91e-5)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" "unprognostic (6.32e-2)" "unprognostic (1.58e-1)" 24.5 29.7 9.0 11.2 10.8 5.5 23.1 10.8 15.6 26.2 11.8 20.5 16.4 26.2 13.2 20.4 25.8 20.9 26.7 9.5 10.3 26.7 20.9 22.8 11.8 11.2 10.2 25.6 25.2 32.7 24.4 12.5 11.0 22.1 10.7 29.7 25.6 13.5 21.0 18.6 18.5 8.4 11.1 20.8 23.0 8.0 9.9 9.8 30.2 21.2 8.7 21.0 20.1 13.0 9.5 23.4 21.1 5.4 44.3 24.0 13.5 15.8 11.7 4.6 5.1 16.7 46.4 7.6 32.7 29.0 9.4 17.5 5.7 26.7 10.7 23.1 15.4 10.7 18.7 6.6 45.2 10.6 17.9 29.6 30.2 13.7 30.3 22.1 14.6 4.6 7.5 19.9 19.6 19.4 9.2 5.9 4.3 18.3 7.0 10.5 139.8 20.0 15.7 19.0 6.6 16.7 15.6 21.3 10.5 4.5 41.1 15.8 27.6 11.3 9.5 5.6 7.4 28.9 8.1 4.1 32.7 6.3 19.2 25.4 26.3 16.4 35.8 28.6 34.8 31.1 28.5 30.7 27.6 31.0 28.3 26.2 5.8 35.4 42.0 58.3 22.1 33.0 9.0 10.8 10.8 15.6 9.5 10.3 11.2 10.2 11.0 11.1 9.9 13.0 37.1 48.1 32.4 8.1 23.8 11.2 46.4 37.4 22.2 43.2 32.0 27.4 5.1 20.0 31.4 31.3 41.7 20.9 29.8 19.9 9.8 37.6 1.2 18.5 32.5 26.7 26.5 8.2 9.1 39.0 15.2 31.7 11.7 20.4 45.0 28.9 22.1 21.6 22.4 21.9 9.1 21.6 32.6 18.0 16.4 1.8 25.7 24.2 32.0 8.4 21.6 62.7 35.0 11.1 13.3 37.6 20.3 17.3 18.4 30.5 30.6 18.1 27.9 60.4 19.7 22.3 31.9 9.2 7.7 16.1 12.6 24.5 20.4 35.3 19.4 31.8 TSPEAR "C21orf29, DFNB98, MGC11251, TSP-EAR" ENSG00000175894 "Thrombospondin type laminin G domain and EAR repeats" Q8WU66 21 44497893-44711572 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 1.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Astrocytes: 1.3;Early spermatids: 3.3;Excitatory neurons: 1.1;Oligodendrocytes: 1.0" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 1.7;U-2 OS: 1.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "CAB034203, CAB034204, HPA052995" Uncertain "Secreted in other tissues" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "CAB034203: AB_1567654, CAB034204: AB_1567655, HPA052995: AB_2682008" "unprognostic (8.61e-3)" "unprognostic (2.45e-1)" "unprognostic (1.86e-4)" "unprognostic (7.87e-3)" "unprognostic (4.08e-2)" "unprognostic (1.00e-3)" "unprognostic (7.92e-3)" "unprognostic (1.56e-1)" "unprognostic (1.34e-1)" "unprognostic (1.15e-2)" "unprognostic (3.86e-4)" "unprognostic (2.13e-2)" "unprognostic (4.80e-7)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.0 1.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 1.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 TSTD3 ENSG00000279170 "Thiosulfate sulfurtransferase like domain containing 3" H0UI37 6 99520976-99589899 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 81.9;Excitatory neurons: 41.7;Inhibitory neurons: 49.4;Oligodendrocyte precursor cells: 62.8;Oligodendrocytes: 93.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 6.1" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.43e-1)" "unprognostic (2.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.70e-2)" "unprognostic (6.01e-2)" "unprognostic (9.22e-2)" "unprognostic (5.74e-2)" "unprognostic (6.38e-2)" "unprognostic (9.44e-3)" "unprognostic (4.70e-2)" "unprognostic (3.56e-2)" "unprognostic (7.83e-3)" "unprognostic (3.13e-1)" "unprognostic (2.00e-1)" "unprognostic (3.62e-2)" "unprognostic (2.88e-3)" 3.9 1.0 0.6 0.8 1.2 1.3 1.2 3.5 2.2 0.5 0.8 1.0 1.2 0.5 1.0 0.4 1.2 1.6 1.5 0.7 0.9 1.4 0.7 1.0 0.6 1.3 0.8 0.6 1.1 3.2 0.7 1.1 2.6 0.9 1.2 1.1 0.8 2.0 1.1 0.7 0.5 0.7 0.6 1.4 0.4 1.1 0.7 2.0 1.1 0.4 0.7 2.5 0.8 1.5 0.8 2.5 4.7 2.2 1.0 0.6 0.8 0.6 0.5 0.9 2.2 0.2 1.1 0.9 3.3 0.8 0.7 1.0 0.5 0.7 0.4 0.2 4.0 1.5 3.1 1.1 1.4 1.3 2.2 0.3 3.5 3.2 1.0 1.2 1.3 6.1 1.4 1.4 0.5 1.2 0.8 3.8 1.3 0.0 1.0 1.9 3.4 0.5 1.1 0.3 1.0 0.7 1.2 4.7 1.6 0.2 0.7 1.1 0.9 0.5 0.6 0.5 0.4 1.8 2.7 0.8 1.6 1.6 0.4 1.1 0.4 0.1 0.6 0.8 0.4 0.3 0.2 1.6 0.3 0.4 1.1 1.4 0.1 0.5 0.1 0.1 0.6 1.2 3.5 2.2 0.7 0.9 1.3 0.8 1.1 0.7 1.1 2.5 1.5 3.2 5.4 81.9 5.5 1.9 4.1 5.8 4.6 1.4 6.2 5.2 0.0 11.5 6.4 12.9 0.0 0.0 2.2 5.2 23.5 4.5 0.3 5.4 4.0 4.1 3.6 9.9 41.7 7.8 0.0 3.6 5.6 3.1 1.3 1.9 7.9 3.4 0.0 0.0 49.4 5.6 14.2 3.2 0.8 1.0 6.5 1.7 5.4 26.2 2.5 7.9 2.1 62.8 93.3 6.5 4.2 9.8 1.4 4.8 5.7 16.3 6.7 2.8 13.1 3.8 4.7 0.8 1.9 4.9 2.0 0.0 3.5 3.0 5.7 4.2 TTBK2 "KIAA0847, SCA11" ENSG00000128881 "Tau tubulin kinase 2" Q6IQ55 15 42738730-42920809 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.8;Inhibitory neurons: 185.1;Late spermatids: 146.2;Oligodendrocytes: 125.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018113, HPA049866" Approved Uncertain "Intermediate filaments" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Intermediate filaments" "HPA018113: AB_1858421, HPA049866: AB_2680923" "unprognostic (2.15e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-1)" "unprognostic (6.30e-2)" "unprognostic (7.73e-2)" "unprognostic (4.26e-1)" "unprognostic (6.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.32e-1)" "unprognostic (2.43e-2)" "unprognostic (2.78e-2)" "unprognostic (8.62e-2)" "unprognostic (3.46e-2)" "unprognostic (7.29e-2)" "unprognostic (3.63e-2)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" 5.3 4.2 7.7 3.0 9.9 5.2 4.4 11.3 20.0 6.0 2.1 6.7 1.6 5.3 3.9 2.6 5.5 3.7 7.2 6.9 13.9 3.4 3.1 4.8 3.4 17.4 9.1 6.4 2.5 4.6 5.6 4.0 18.9 4.7 3.0 17.7 3.2 3.8 10.4 3.1 3.9 5.0 6.3 4.3 3.4 33.4 16.9 5.2 3.8 6.3 3.1 5.3 4.7 13.8 5.7 3.8 8.4 4.2 6.5 6.6 1.8 4.6 7.4 4.5 6.9 4.3 1.3 3.3 6.1 4.7 9.2 3.9 8.1 6.7 6.8 13.0 3.6 4.8 6.9 1.6 5.0 6.7 7.8 4.7 6.5 3.9 21.1 9.9 5.2 5.1 7.0 4.9 4.5 0.9 4.1 4.3 2.3 1.7 3.8 7.2 9.1 1.7 5.8 4.0 6.6 6.5 12.6 0.9 2.5 5.8 2.6 8.7 5.8 5.1 4.7 5.7 6.0 7.1 11.3 5.5 3.9 5.8 3.0 0.1 0.5 0.2 0.2 0.3 0.5 0.3 0.2 0.2 0.1 0.3 0.3 0.2 0.2 0.4 0.2 0.2 0.1 0.1 7.7 9.9 11.3 20.0 6.9 13.9 17.4 9.1 18.9 6.3 16.9 13.8 16.2 6.4 11.8 75.7 11.5 10.7 12.1 11.8 26.2 36.3 9.6 7.6 17.6 12.8 10.0 9.2 37.5 4.1 9.1 3.9 0.0 5.7 80.5 24.9 11.7 17.0 14.3 17.4 153.8 4.3 3.2 15.5 4.6 4.6 19.0 16.2 17.5 9.8 7.4 45.4 185.1 5.1 2.0 16.0 25.9 146.2 16.8 16.4 12.4 69.3 16.9 16.5 6.2 97.5 125.6 7.5 2.6 20.3 6.6 12.4 5.5 5.5 40.5 39.4 13.1 24.6 16.3 34.5 10.1 12.5 9.2 3.1 13.4 11.3 5.3 7.4 TTC13 FLJ22584 ENSG00000143643 "Tetratricopeptide repeat domain 13" Q8NBP0 1 230906243-230978875 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 42.7;Excitatory neurons: 70.9;Inhibitory neurons: 76.7;Microglial cells: 56.2;Oligodendrocyte precursor cells: 41.7;Oligodendrocytes: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018022, HPA051558" Uncertain Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA018022: AB_2211524, HPA051558: AB_2681534" "unprognostic (2.68e-1)" "unprognostic (1.64e-1)" "unprognostic (3.42e-1)" "unprognostic (9.59e-3)" "unprognostic (8.10e-2)" "prognostic favorable (7.66e-4)" "unprognostic (2.60e-2)" "unprognostic (5.40e-3)" "unprognostic (1.97e-1)" "unprognostic (1.80e-2)" "prognostic favorable (4.59e-5)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.60e-11)" "unprognostic (4.48e-2)" "unprognostic (3.01e-1)" "unprognostic (5.96e-2)" "unprognostic (7.54e-3)" 7.8 5.1 7.4 11.7 9.4 11.6 7.0 7.9 7.9 7.1 4.8 11.2 8.0 5.9 6.5 6.0 6.5 6.1 6.5 7.3 9.2 6.4 7.9 9.9 19.6 7.3 6.7 5.6 10.5 6.8 9.2 7.5 7.5 6.3 15.9 11.8 6.7 5.1 11.4 9.8 12.2 6.1 7.7 20.3 12.2 2.9 8.4 10.2 6.8 6.2 14.8 6.5 6.7 9.5 12.4 12.4 12.0 23.5 11.0 7.1 24.5 17.7 13.9 9.8 11.0 18.4 13.2 22.7 15.9 10.8 9.7 19.4 8.0 6.6 6.5 25.6 23.3 6.8 13.7 12.5 11.6 14.1 6.0 6.3 11.4 9.2 8.5 9.8 17.5 9.7 7.3 12.9 9.1 6.5 7.5 13.5 13.5 41.1 15.2 12.0 17.2 31.9 10.2 8.5 16.5 14.2 13.5 13.8 24.2 5.2 14.8 18.1 9.0 11.5 1.6 15.7 31.9 15.8 27.9 6.8 11.3 8.8 19.2 5.7 5.5 4.9 6.6 4.1 4.5 2.8 4.5 5.3 7.7 2.2 3.5 4.4 1.9 7.9 5.3 4.9 3.9 4.2 7.4 9.4 7.9 7.9 7.3 9.2 7.3 6.7 7.5 7.7 8.4 9.5 7.2 6.4 7.4 42.7 18.9 3.3 1.0 1.8 1.2 6.1 3.4 2.4 3.0 1.5 4.0 1.8 6.2 4.3 21.8 6.6 1.9 5.6 1.7 1.7 2.4 5.4 6.1 11.6 70.9 8.6 5.1 5.2 14.3 3.0 9.5 4.6 1.8 5.0 5.0 11.8 76.7 11.3 8.2 7.8 6.6 2.3 2.8 8.9 1.8 56.2 7.2 4.5 17.5 41.7 70.6 4.1 8.7 6.8 13.6 1.9 2.6 1.2 1.3 10.8 6.6 5.5 4.9 3.1 3.5 3.8 2.7 1.6 16.9 2.1 9.4 1.6 TTC17 FLJ10890 ENSG00000052841 "Tetratricopeptide repeat domain 17" Q96AE7 11 43358920-43494933 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038508 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Cytosol "HPA038508: AB_10671744" "unprognostic (2.71e-1)" "unprognostic (4.04e-3)" "unprognostic (6.48e-2)" "unprognostic (2.64e-1)" "unprognostic (1.17e-1)" "unprognostic (5.66e-2)" "unprognostic (1.74e-1)" "unprognostic (9.03e-2)" "unprognostic (5.01e-3)" "unprognostic (2.62e-1)" "unprognostic (1.34e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.75e-6)" "unprognostic (1.04e-2)" "unprognostic (4.40e-1)" "unprognostic (1.18e-1)" "unprognostic (1.54e-2)" 20.7 18.7 11.0 16.1 11.3 15.5 28.6 16.7 12.2 22.0 22.0 21.2 21.6 26.9 25.0 14.2 28.4 22.3 13.5 11.1 12.2 19.4 38.6 24.2 20.2 11.9 12.5 40.9 49.5 27.7 12.3 29.2 11.7 25.4 22.9 25.1 40.7 21.4 16.4 19.5 25.5 23.0 11.0 23.4 27.4 24.8 12.4 24.6 36.9 20.0 22.4 18.8 15.6 13.0 15.0 30.4 31.3 49.3 77.2 63.6 22.1 35.6 47.6 29.3 35.1 21.1 21.7 31.6 34.9 35.9 33.7 31.1 22.3 23.5 35.2 24.5 29.0 24.2 19.5 20.8 95.3 36.6 29.9 59.5 69.8 21.3 68.4 66.2 29.5 22.7 35.5 26.2 29.8 18.1 27.1 20.3 46.8 58.0 25.0 25.1 33.3 36.9 37.2 21.4 16.7 39.7 27.7 73.1 44.6 31.4 68.6 40.8 39.6 41.7 18.4 47.1 52.1 51.1 44.5 29.8 26.9 21.6 45.3 20.0 21.7 19.0 14.9 22.4 15.9 16.4 16.2 14.5 16.9 14.8 16.3 15.1 18.5 16.5 20.8 17.6 16.1 18.0 11.0 11.3 16.7 12.2 11.1 12.2 11.9 12.5 11.7 11.0 12.4 13.0 43.0 64.1 62.7 159.6 53.3 42.1 35.0 36.4 30.7 44.1 40.3 35.7 20.5 31.5 51.9 22.0 60.5 32.6 43.8 30.7 3.9 23.1 52.6 35.8 44.5 40.9 22.3 44.0 204.6 43.4 28.8 44.4 40.2 48.6 36.6 56.2 40.0 57.5 26.2 47.1 203.2 42.1 34.6 48.0 32.3 18.4 57.2 37.1 28.4 181.8 47.8 24.8 37.0 192.0 200.6 29.7 31.5 36.5 48.9 50.1 47.7 15.5 54.3 47.3 52.6 45.5 36.2 51.8 35.0 34.6 43.2 30.8 45.6 33.5 35.8 42.7 TTC19 "FLJ20343, MGC19520" ENSG00000011295 "Tetratricopeptide repeat domain 19" Q6DKK2 17 15999784-16045015 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023010, HPA052380" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA023010: AB_1858429, HPA052380: AB_2681806" "unprognostic (1.04e-2)" "unprognostic (4.90e-3)" "unprognostic (2.87e-2)" "unprognostic (4.80e-3)" "unprognostic (8.09e-2)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.84e-2)" "unprognostic (8.34e-2)" "unprognostic (1.72e-2)" "unprognostic (2.30e-3)" "unprognostic (5.14e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.31e-1)" "unprognostic (3.22e-1)" "unprognostic (4.85e-2)" "unprognostic (2.24e-1)" 6.6 11.4 8.1 3.8 7.8 11.2 7.5 19.4 11.6 6.9 8.4 8.0 10.3 6.9 5.2 6.8 5.8 5.2 8.6 8.8 9.6 8.7 7.7 6.6 4.6 7.9 7.4 6.9 12.4 11.2 8.0 5.8 7.9 6.8 5.7 9.9 9.1 4.2 8.8 9.5 9.8 3.8 6.3 4.5 8.4 3.6 8.0 3.9 10.6 4.4 3.3 6.3 6.7 10.5 7.0 4.1 7.6 12.1 6.4 5.6 4.0 3.1 4.6 3.1 3.8 6.5 12.8 8.9 9.8 4.3 4.6 9.1 9.9 8.3 3.8 12.5 10.2 8.2 9.2 6.3 9.1 9.3 11.6 5.6 7.0 2.6 11.4 9.6 7.1 12.4 4.6 7.7 6.8 7.6 7.5 6.8 10.0 11.8 3.0 7.8 8.0 8.2 11.6 10.5 6.6 5.5 7.6 9.8 16.6 24.6 6.9 4.6 13.1 4.2 1.2 6.1 7.5 4.8 1.5 4.2 9.8 9.8 9.5 5.2 0.7 1.8 0.7 0.7 1.2 0.9 0.9 1.2 0.7 1.1 1.0 1.3 0.7 0.6 0.7 1.1 1.0 0.4 8.1 7.8 19.4 11.6 8.8 9.6 7.9 7.4 7.9 6.3 8.0 10.5 51.0 41.7 38.6 69.5 60.8 105.3 83.5 30.8 70.6 147.8 65.1 47.9 34.8 42.9 35.4 46.0 143.9 75.7 62.8 59.7 70.5 50.0 59.4 49.4 41.5 60.3 45.6 32.4 115.1 41.2 41.9 34.2 43.8 67.9 31.1 46.8 42.8 36.0 25.6 129.5 100.9 52.3 26.4 25.8 76.7 7.2 41.0 46.5 55.2 35.6 34.8 73.9 70.0 54.3 57.8 47.7 57.9 33.4 34.5 89.1 75.4 47.1 26.5 180.4 46.0 56.5 40.2 30.2 31.1 56.9 116.8 65.5 68.9 69.9 63.3 72.7 TTC9B FLJ30373 ENSG00000174521 "Tetratricopeptide repeat domain 9B" Q8N6N2 19 40216058-40218399 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 41 "brain: 110.8;choroid plexus: 32.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 39.1;Excitatory neurons: 39.3;Horizontal cells: 18.5;Inhibitory neurons: 19.7;Oligodendrocyte precursor cells: 27.2" "Cancer enriched" "Detected in single" 15 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "SCLC-21H: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042496 Approved Approved Nucleoplasm,Vesicles,Mitochondria "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Mitochondria" Vesicles "HPA042496: AB_10795506" "unprognostic (2.31e-1)" "unprognostic (1.39e-4)" "unprognostic (5.09e-2)" "unprognostic (5.24e-2)" "unprognostic (8.47e-2)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (7.95e-2)" "unprognostic (2.78e-1)" "unprognostic (1.54e-2)" "unprognostic (3.69e-1)" "unprognostic (8.75e-6)" "unprognostic (1.39e-1)" "unprognostic (8.23e-2)" "unprognostic (1.95e-1)" "unprognostic (5.24e-2)" 0.0 0.6 73.9 0.3 74.7 0.0 0.0 49.7 110.8 0.0 32.9 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 84.2 60.6 0.2 0.0 0.0 0.0 45.1 46.3 0.0 0.0 0.0 0.9 0.0 46.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.5 0.1 43.0 0.0 0.2 0.3 60.4 0.0 0.0 0.0 0.0 0.0 0.1 69.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 26.8 1.4 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.4 0.1 0.0 0.3 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 73.9 74.7 49.7 110.8 84.2 60.6 45.1 46.3 46.4 43.0 60.4 69.0 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.1 0.0 39.1 0.2 0.0 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.8 0.2 0.2 1.8 0.0 39.3 0.5 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 18.5 19.7 0.1 0.0 0.0 0.0 1.0 0.3 0.0 0.0 4.7 0.0 1.7 0.0 27.2 5.0 0.1 1.2 0.7 0.0 0.1 0.0 0.0 1.2 8.4 0.0 0.0 0.1 7.0 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 TTLL6 FLJ35808 ENSG00000170703 "Tubulin tyrosine ligase like 6" Q8N841 17 48762235-48817214 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 18.9" "Group enriched" "Detected in some" 4 "Early spermatids: 49.7;Late spermatids: 176.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HDLM-2: 4.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA052397 Enhanced Approved Vesicles,Microtubules NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" Microtubules Vesicles "HPA052397: AB_2681812" "unprognostic (5.74e-2)" "unprognostic (3.29e-1)" "unprognostic (1.26e-1)" "unprognostic (2.18e-1)" "unprognostic (8.04e-2)" "unprognostic (2.95e-1)" "unprognostic (1.85e-2)" "unprognostic (1.02e-1)" "unprognostic (1.27e-2)" "unprognostic (2.35e-1)" "unprognostic (2.21e-5)" "unprognostic (1.10e-2)" "unprognostic (6.01e-5)" "unprognostic (1.17e-1)" "unprognostic (3.28e-1)" "unprognostic (6.68e-2)" "unprognostic (2.09e-3)" 0.1 0.0 0.6 0.1 0.6 0.0 0.1 0.5 1.0 0.2 1.6 2.8 1.3 0.1 0.0 0.0 3.6 0.5 0.0 0.7 0.6 2.5 0.0 0.6 0.0 0.8 0.9 0.0 0.6 0.0 0.4 0.0 0.6 0.1 3.9 0.4 0.0 0.0 0.0 0.0 1.7 0.1 0.6 0.0 0.2 18.9 0.8 0.1 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.5 1.0 0.7 0.6 0.8 0.9 0.6 0.6 0.8 0.6 0.1 3.2 2.6 5.2 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.6 0.0 3.8 1.8 0.0 0.0 0.0 7.4 1.9 0.3 49.7 2.6 0.1 0.5 4.2 0.0 1.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.1 0.1 0.0 1.0 2.6 0.0 0.0 0.0 176.1 1.2 0.1 0.0 0.0 0.0 0.4 0.0 13.0 0.7 0.0 2.2 0.0 0.0 0.4 4.1 3.2 23.8 0.7 0.0 0.0 0.0 11.2 0.4 0.0 0.0 0.0 0.0 0.4 3.5 0.1 TTR "CTS, CTS1, HsT2651, PALB" ENSG00000118271 Transthyretin P02766 18 31557009-31598833 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Transport "Hormone, Thyroid hormone" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "choroid plexus: 142023.1" "Cell type enriched" "Detected in many" 30 "Hepatocytes: 23659.3" "Group enriched" "Detected in many" 28 "liver cancer: 928.2;pancreatic cancer: 666.0" "Group enriched" "Detected in all" 7 "cerebellum: 621.7;hippocampal formation: 1730.9;thalamus: 688.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 160.1;EFO-21: 39.6;Hep G2: 249.0;U-2 OS: 57.0" "Group enriched" "Detected in all" 5 "basal ganglia: 1538.3;hippocampal formation: 4891.0;pons and medulla: 5758.5;thalamus: 3400.4" "Region enhanced" "Detected in all" "medulla oblongata: 1381.8" "CAB002517, HPA002550, CAB062567, CAB073406" Supported Approved "Golgi apparatus" "Secreted to blood" NA NA 345000000000 99000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "CAB002517: AB_563965, CAB062567: AB_2665620, CAB073406: , HPA002550: AB_1080419" "unprognostic (6.79e-3)" "unprognostic (3.38e-2)" "unprognostic (4.10e-1)" "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (8.15e-2)" "unprognostic (3.74e-2)" "unprognostic (9.66e-3)" "unprognostic (8.72e-2)" "unprognostic (1.23e-2)" "unprognostic (8.35e-3)" "unprognostic (5.26e-1)" "unprognostic (3.52e-2)" 4.2 0.6 148.5 0.5 56.7 9.6 0.4 621.7 83.7 2.0 142023.1 6.0 14.9 1.3 0.9 2.2 0.8 51.2 2.9 1730.9 37.3 18.4 21288.1 0.8 2.4 106.5 86.0 1.1 1785.1 186.8 6.0 2.7 27.1 1.6 4.5 80.1 1.8 0.4 1.1 15.6 6.8 0.3 12.3 3.8 49.8 2.3 688.2 1.1 1.3 0.0 0.1 2.3 0.6 133.9 1.6 0.4 0.6 0.5 0.8 0.1 1.0 0.8 0.3 0.0 0.0 160.1 0.0 2.9 39.6 0.5 0.6 0.4 0.0 0.3 0.0 5.9 0.8 5.2 1.8 249.0 0.4 11.2 1.0 0.1 0.1 0.1 0.0 0.7 0.0 0.3 2.8 0.4 0.0 0.5 0.4 0.7 0.6 4.5 0.3 0.3 7.4 0.2 0.3 1.6 0.9 1.1 5.8 0.0 0.2 1.7 0.6 0.2 1.7 2.4 57.0 0.5 4.3 1.0 2.6 17.6 0.7 4.3 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.1 0.0 0.1 0.0 0.0 148.5 56.7 621.7 83.7 1730.9 37.3 106.5 86.0 27.1 12.3 688.2 133.9 0.0 0.0 0.0 0.0 15.1 0.5 0.0 0.0 0.0 144.8 0.0 0.0 1.8 779.2 0.0 5.5 162.6 0.3 0.0 1.5 5.9 3.1 6.8 0.5 0.5 14.1 356.2 192.5 0.0 2.0 3.6 0.7 13.3 0.0 0.0 0.2 192.4 23659.3 2.4 26.9 0.1 19.6 0.0 313.7 0.0 8.7 0.3 1.2 0.0 0.0 0.0 24.9 0.0 0.0 0.0 130.5 5.2 0.0 0.0 0.2 1.3 26.9 0.0 56.0 0.0 0.0 0.3 3.3 1.1 0.0 0.1 4.0 10.9 0.0 1.7 0.0 TUBB4A "beta-5, DYT4, TUBB4" ENSG00000104833 "Tubulin beta 4A class IVa" P04350 19 6494319-6502848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Dystonia, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 828.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 22.2;Muller glia cells: 33.0;Oligodendrocytes: 94.1;Theca cells: 81.7" "Group enriched" "Detected in many" 9 "glioma: 50.1;melanoma: 83.2;testis cancer: 49.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 13 "B-cells: 3.8;T-cells: 5.4" "Cell line enhanced" "Detected in many" "AN3-CA: 100.7;HAP1: 58.3;HEL: 91.7;PC-3: 49.6;REH: 43.4;SH-SY5Y: 36.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010768, HPA043640, HPA046280" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA 110000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010768: AB_261775, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.05e-1)" "unprognostic (1.97e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (8.42e-7)" "unprognostic (3.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.11e-1)" "unprognostic (8.08e-2)" "unprognostic (6.69e-2)" "unprognostic (1.54e-1)" "unprognostic (1.11e-1)" "unprognostic (3.46e-2)" "unprognostic (1.12e-3)" "unprognostic (1.36e-2)" "unprognostic (1.58e-1)" "unprognostic (2.06e-1)" "unprognostic (2.30e-1)" 0.9 203.4 209.7 1.7 404.6 0.2 0.6 452.3 388.7 0.6 0.0 6.3 1.1 0.6 0.3 0.7 0.9 0.6 2.5 249.2 229.1 2.2 1.2 0.6 1.1 425.9 254.4 1.5 3.0 0.6 4.0 0.7 440.0 0.8 0.8 22.6 1.2 0.4 4.4 5.2 3.0 0.8 221.4 9.5 2.1 76.0 373.5 0.3 0.6 1.0 0.7 0.6 1.8 828.2 0.2 28.3 0.1 100.7 0.2 0.0 0.2 0.7 0.0 0.1 0.0 1.4 0.4 0.1 30.3 0.0 3.5 0.7 58.3 0.0 0.6 0.0 10.7 91.7 1.9 0.9 0.0 0.0 5.5 0.0 0.0 2.3 0.0 1.0 0.0 17.1 8.6 0.8 0.0 3.0 18.1 4.1 7.5 0.0 49.6 43.4 0.1 20.3 10.9 0.1 0.2 36.6 0.3 0.2 30.9 2.7 0.8 1.9 0.0 0.2 12.2 0.1 0.4 2.4 1.7 11.7 1.1 0.1 0.5 0.0 0.0 0.0 5.4 0.0 3.3 3.8 0.7 5.0 0.0 1.1 1.6 3.8 0.1 0.3 0.0 0.0 0.0 1.4 209.7 404.6 452.3 388.7 249.2 229.1 425.9 254.4 440.0 221.4 373.5 828.2 0.1 0.0 0.0 6.8 3.2 1.9 0.7 0.3 0.0 2.8 0.1 0.1 9.8 1.5 0.0 0.0 0.0 0.2 1.6 0.1 5.9 1.6 2.9 0.1 0.2 1.2 0.0 2.1 22.2 0.0 0.2 1.8 0.0 0.1 0.0 16.3 1.4 0.3 0.4 10.1 15.0 0.0 0.0 0.0 1.2 9.4 5.3 0.3 14.2 13.1 0.0 33.0 1.0 8.5 94.1 0.1 0.0 0.4 0.9 0.2 0.0 1.8 0.5 2.3 6.6 0.4 4.6 1.9 1.1 0.0 1.6 0.1 3.8 81.7 0.0 0.2 TUBD1 "FLJ12709, TUBD" ENSG00000108423 "Tubulin delta 1" Q9UJT1 17 59859479-59892945 "FDA approved drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 83.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004609, HPA023980, HPA027090" Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 13: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cytosol" "CAB004609: AB_628416, HPA023980: AB_1858456, HPA027090: AB_1858457" "unprognostic (1.92e-1)" "unprognostic (5.95e-2)" "prognostic favorable (2.04e-4)" "unprognostic (1.39e-1)" "unprognostic (1.32e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (1.00e-5)" "unprognostic (2.86e-2)" "unprognostic (8.87e-3)" "unprognostic (1.02e-1)" "unprognostic (1.77e-3)" "unprognostic (2.59e-1)" "prognostic unfavorable (6.06e-4)" "unprognostic (4.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.36e-1)" "unprognostic (8.83e-2)" 4.4 4.4 5.8 4.9 6.9 3.9 7.0 9.2 7.4 7.5 5.0 7.5 3.8 5.5 9.1 10.6 6.5 4.6 6.0 5.9 6.3 6.2 5.9 5.1 6.7 6.7 6.9 9.0 7.8 5.9 6.9 4.2 7.0 7.8 4.7 5.6 7.0 6.2 6.5 6.8 4.8 4.3 6.3 5.8 6.4 5.5 6.2 8.2 7.3 7.7 8.3 6.4 8.3 8.9 11.7 15.8 12.2 12.8 6.8 4.9 9.7 9.1 5.3 11.7 9.5 17.0 7.5 10.5 15.0 2.1 7.9 9.7 17.4 5.4 11.1 6.1 21.2 12.6 12.4 20.4 3.6 7.6 6.4 2.7 8.3 10.1 3.5 4.0 9.4 10.3 27.5 7.1 4.0 83.1 15.6 8.5 10.8 13.0 6.9 16.1 17.9 16.2 5.0 4.8 11.3 6.8 6.4 4.9 6.5 14.5 11.8 7.2 3.0 8.4 18.3 5.9 9.8 8.3 13.7 16.2 4.0 8.3 7.5 6.5 8.4 16.3 11.4 5.8 13.2 11.7 14.0 12.1 5.9 8.9 18.1 14.8 8.8 10.1 6.5 9.9 16.7 7.1 5.8 6.9 9.2 7.4 5.9 6.3 6.7 6.9 7.0 6.3 6.2 8.9 8.3 12.8 36.1 10.7 16.9 15.7 14.4 9.1 10.8 7.6 10.9 11.3 5.3 5.7 17.6 3.7 6.2 6.3 9.4 3.2 11.7 5.7 1.7 9.2 8.5 9.4 10.3 13.9 9.2 4.8 7.4 9.6 4.1 16.3 11.4 9.9 8.9 3.8 4.0 3.3 9.5 5.5 8.2 4.7 7.1 0.8 5.6 6.9 7.2 9.4 6.0 10.3 13.4 8.5 18.4 3.7 7.5 8.2 10.9 12.5 3.6 3.6 9.4 8.6 6.6 13.3 9.6 14.7 24.2 10.6 16.9 4.0 16.2 2.6 4.9 6.8 TUBGCP5 "GCP5, KIAA1899" ENSG00000275835 "Tubulin gamma complex associated protein 5" Q96RT8 15 22983192-23039572 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039366, HPA040366" Supported Supported Centrosome,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Centrosome, Cytosol" "HPA039366: AB_10673243, HPA040366: AB_2676942" "unprognostic (1.17e-2)" "unprognostic (2.21e-1)" "unprognostic (1.30e-1)" "unprognostic (4.27e-3)" "unprognostic (2.94e-1)" "unprognostic (2.79e-1)" "unprognostic (9.45e-2)" "unprognostic (4.97e-2)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (1.04e-1)" "unprognostic (2.27e-1)" "unprognostic (1.42e-2)" "unprognostic (1.18e-2)" "unprognostic (6.40e-2)" "unprognostic (1.13e-2)" "unprognostic (9.53e-3)" 8.4 9.1 3.5 6.5 4.2 9.0 9.7 3.8 6.6 9.7 1.8 7.3 6.3 9.7 5.7 8.0 6.7 6.0 9.1 3.3 4.7 8.2 9.3 7.0 8.4 4.8 4.1 7.4 10.6 8.4 8.0 6.9 5.1 9.6 7.3 9.8 6.7 7.7 10.7 10.0 6.3 8.7 3.3 7.2 7.8 13.4 4.3 8.9 11.2 10.2 8.7 7.6 7.6 6.5 20.3 20.8 23.9 14.4 18.3 11.9 13.8 24.3 26.6 26.2 22.7 16.1 9.3 16.0 10.3 22.3 13.8 19.8 16.0 18.8 21.8 23.6 6.6 26.9 21.2 8.8 6.4 27.7 11.6 19.4 7.2 17.5 16.2 8.6 16.1 26.4 19.8 23.6 16.9 13.1 18.8 12.1 14.2 19.8 18.8 22.9 26.1 3.2 15.3 30.6 8.3 14.0 19.7 14.2 12.7 11.8 22.2 13.4 13.9 18.4 11.7 14.0 36.6 18.3 19.8 40.0 23.8 18.3 17.3 0.2 1.4 0.6 2.6 2.1 2.7 2.2 4.0 4.4 2.3 4.2 3.5 4.7 1.5 3.9 2.1 2.5 3.7 1.7 3.5 4.2 3.8 6.6 3.3 4.7 4.8 4.1 5.1 3.3 4.3 6.5 7.4 16.0 17.7 16.0 11.0 3.3 3.2 4.2 9.1 27.6 5.2 5.0 13.2 7.2 6.3 5.5 14.6 8.3 11.6 3.0 5.9 6.5 7.8 12.5 13.4 6.4 4.2 3.8 21.4 4.6 7.2 10.4 6.1 6.2 6.3 31.4 5.7 10.2 7.9 10.1 29.7 4.7 4.1 5.2 2.9 13.4 11.1 6.2 3.6 12.2 5.1 11.6 7.2 15.6 26.2 6.6 5.0 12.8 7.9 2.3 2.9 7.1 9.0 18.9 0.0 13.6 10.6 35.0 36.7 8.6 2.7 3.4 9.6 14.1 4.6 2.0 TUSC2 "C3orf11, FUS1, PAP, PDAP2" ENSG00000114383 "Tumor suppressor 2, mitochondrial calcium regulator" O75896 3 50320027-50328251 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030116 Approved Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" Cytosol Vesicles "HPA030116: AB_10602253" "unprognostic (1.58e-2)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (8.46e-2)" "unprognostic (2.73e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.53e-3)" "unprognostic (2.87e-1)" "unprognostic (1.20e-2)" "unprognostic (3.47e-2)" "unprognostic (1.99e-2)" "prognostic favorable (8.70e-7)" "unprognostic (9.22e-3)" "unprognostic (1.98e-1)" "unprognostic (3.15e-1)" "unprognostic (6.34e-3)" 17.7 25.4 53.4 14.9 54.1 12.4 17.0 51.0 56.2 16.3 43.9 25.2 12.8 17.7 28.2 18.9 20.6 11.5 35.4 54.8 55.5 29.2 25.9 18.4 17.1 54.6 56.2 15.8 27.4 34.8 21.5 17.3 55.6 22.1 16.6 36.0 18.4 17.8 50.9 13.8 20.3 13.7 50.5 23.7 26.9 22.6 56.1 20.4 23.1 36.4 20.5 20.5 14.2 50.8 24.7 20.2 27.5 30.1 29.8 15.4 30.1 19.3 26.5 36.3 30.7 35.6 22.0 41.8 21.0 18.3 37.4 15.5 33.9 25.7 31.7 24.8 31.2 20.6 18.6 38.7 26.1 36.7 34.8 16.8 40.7 36.5 18.1 25.5 38.0 32.8 25.4 19.6 21.1 18.8 38.7 46.5 37.6 30.4 28.9 13.3 13.4 34.4 36.9 26.4 14.7 30.3 14.4 25.4 29.9 27.2 24.2 44.3 30.3 10.8 26.6 24.8 40.2 47.6 79.7 29.4 24.2 24.1 17.4 16.7 21.2 34.6 24.0 19.6 24.3 23.0 20.8 25.2 14.2 24.6 23.5 25.2 30.2 22.4 18.1 26.3 25.2 32.3 53.4 54.1 51.0 56.2 54.8 55.5 54.6 56.2 55.6 50.5 56.1 50.8 39.8 12.8 17.0 3.9 41.7 57.5 36.8 60.7 37.0 55.5 61.0 44.2 39.6 55.8 37.9 57.0 22.9 62.9 54.4 46.5 115.4 73.9 123.1 55.6 15.8 39.2 50.4 40.4 12.9 74.1 55.5 24.9 25.0 28.4 29.9 16.4 40.4 72.7 76.6 74.0 11.4 46.1 73.2 46.1 51.1 351.8 27.1 37.7 55.2 5.6 57.6 69.0 59.8 4.0 7.8 74.0 61.0 24.8 45.8 67.8 72.0 178.6 71.5 45.5 13.1 18.0 38.5 54.1 49.2 47.4 91.2 69.6 38.7 28.9 46.1 63.7 TWSG1 TSG ENSG00000128791 "Twisted gastrulation BMP signaling modulator 1" Q9GZX9 18 9334767-9402420 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 141.2;Peritubular cells: 95.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014898 Uncertain Supported Centrosome,Cytosol "Secreted - unknown location" No No 3500000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Centrosome, Cytosol" "HPA014898: AB_1858467" "unprognostic (2.55e-1)" "unprognostic (3.17e-2)" "unprognostic (7.31e-2)" "unprognostic (8.95e-3)" "unprognostic (2.92e-3)" "unprognostic (1.83e-1)" "unprognostic (8.29e-2)" "unprognostic (5.88e-2)" "unprognostic (6.33e-2)" "unprognostic (1.05e-2)" "unprognostic (3.10e-2)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (4.36e-2)" "unprognostic (8.73e-2)" "unprognostic (1.79e-1)" "unprognostic (1.32e-2)" 23.7 19.5 7.7 16.7 9.6 8.2 17.5 9.2 12.2 40.6 12.7 22.1 11.1 51.3 45.8 26.1 30.5 36.3 18.6 7.4 9.2 36.3 10.0 19.7 11.8 10.5 9.4 32.3 9.7 33.2 9.8 24.8 10.4 43.0 22.4 5.7 11.1 64.6 5.7 12.9 12.5 80.1 9.7 13.6 14.9 11.8 8.9 7.0 34.9 16.5 14.9 34.7 16.2 11.0 57.3 19.9 57.6 28.6 111.2 99.7 26.6 107.2 132.4 57.6 81.9 21.2 73.5 8.2 52.7 142.5 37.4 19.5 57.1 42.4 105.3 22.0 15.4 14.7 15.9 10.8 98.7 10.8 29.4 102.0 34.1 48.3 23.3 78.7 90.8 7.8 22.7 14.6 149.2 17.0 11.9 13.2 18.9 33.6 16.1 20.7 58.7 5.0 65.7 75.2 7.4 20.0 83.3 23.1 22.9 23.9 26.1 25.0 75.6 104.9 52.4 99.5 67.5 21.2 20.1 15.1 64.5 14.9 37.9 8.3 2.7 4.0 4.3 1.5 2.8 2.1 2.0 4.5 5.5 1.6 2.3 4.8 1.2 2.9 0.5 5.3 1.0 2.1 7.7 9.6 9.2 12.2 7.4 9.2 10.5 9.4 10.4 9.7 8.9 11.0 9.0 25.6 18.4 13.1 8.1 39.6 21.3 18.5 51.2 4.8 18.5 11.6 7.8 10.0 21.0 75.4 0.0 6.3 12.1 12.1 1.9 9.1 141.2 13.3 38.6 18.1 6.0 9.9 28.0 7.6 18.3 61.9 10.2 23.4 6.3 31.6 17.2 7.5 16.0 3.3 31.0 8.2 57.0 9.4 30.1 30.7 37.6 12.2 23.2 17.8 15.3 16.1 7.2 29.1 31.6 9.2 10.7 95.2 17.8 46.3 1.3 12.6 12.4 5.0 72.3 28.9 56.6 24.6 9.6 26.6 26.9 4.7 10.1 20.4 12.2 27.1 TXNDC12 "AGR1, ERP18, ERP19, hAG-1, PDIA16, TLP19" ENSG00000117862 "Thioredoxin domain containing 12" O95881 1 52020131-52055191 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 160000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.54e-2)" "unprognostic (5.46e-2)" "prognostic favorable (4.44e-4)" "unprognostic (2.33e-3)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.61e-4)" "prognostic unfavorable (1.28e-5)" "unprognostic (1.25e-1)" "unprognostic (3.28e-2)" "unprognostic (1.17e-1)" "unprognostic (6.14e-2)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.40e-12)" "unprognostic (2.13e-1)" "unprognostic (5.83e-2)" "unprognostic (1.73e-2)" "unprognostic (1.17e-1)" 49.6 47.7 39.7 45.7 40.7 51.3 50.8 41.2 48.0 49.2 44.2 60.8 47.0 40.8 62.9 31.2 56.8 46.5 36.6 40.1 47.0 54.0 74.1 46.9 50.1 42.5 41.6 47.8 56.5 46.7 21.9 54.5 43.1 40.8 66.1 28.6 57.6 36.5 18.2 29.9 48.4 40.8 44.1 46.4 56.4 38.9 42.8 52.3 52.6 30.2 54.4 57.5 18.0 46.1 97.1 88.9 96.0 135.4 160.1 83.9 76.4 143.5 143.8 132.7 150.7 99.8 78.2 73.0 93.8 118.1 141.1 127.3 134.5 112.9 178.2 94.1 124.2 93.1 73.3 163.2 165.7 176.8 181.8 120.5 132.0 134.0 203.3 99.0 135.4 89.1 87.1 48.2 111.9 91.4 89.3 233.6 208.0 138.8 85.9 94.2 143.3 207.1 178.6 85.3 68.3 97.3 143.9 123.5 138.7 187.7 69.6 228.1 86.5 93.9 100.1 106.7 166.1 107.2 183.6 84.2 131.0 164.9 108.2 355.3 224.0 356.5 135.3 215.0 170.8 160.1 164.3 145.3 169.2 146.0 156.7 151.1 393.2 150.0 234.2 180.6 220.0 273.3 39.7 40.7 41.2 48.0 40.1 47.0 42.5 41.6 43.1 44.1 42.8 46.1 89.8 9.6 12.3 9.4 50.4 44.1 63.1 78.9 35.3 18.3 53.6 57.0 13.6 62.9 30.4 44.1 14.6 115.5 58.9 35.3 17.6 75.4 13.3 42.5 54.7 62.3 48.5 25.7 15.0 89.4 170.9 52.1 23.4 49.2 33.0 106.3 55.6 31.0 120.8 21.9 14.7 70.5 50.8 59.1 55.7 7.2 55.9 66.0 51.6 19.7 66.6 39.2 50.4 10.1 15.9 73.0 57.0 30.9 68.7 68.7 65.4 36.1 32.3 17.0 32.9 40.7 47.1 60.4 9.7 36.0 45.5 118.5 52.3 75.4 71.2 60.4 TXNDC15 "2310047H23Rik, C5orf14, FLJ22625" ENSG00000113621 "Thioredoxin domain containing 15" Q96J42 5 134874371-134901635 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 203.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015483 Approved Approved "Golgi apparatus" NA NA 49000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA015483: AB_1845722" "unprognostic (1.56e-1)" "unprognostic (1.22e-2)" "unprognostic (2.29e-2)" "unprognostic (3.73e-2)" "unprognostic (2.14e-2)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.86e-2)" "unprognostic (7.95e-2)" "unprognostic (6.68e-2)" "unprognostic (9.71e-3)" "unprognostic (3.88e-2)" "prognostic unfavorable (1.44e-4)" "unprognostic (2.36e-1)" "unprognostic (4.37e-1)" "unprognostic (1.41e-3)" "unprognostic (1.50e-1)" 34.1 44.7 20.3 34.9 23.2 8.9 33.9 22.8 23.2 42.5 39.1 37.3 23.7 35.0 56.1 22.3 29.5 32.5 35.8 20.8 24.2 29.0 33.7 30.5 25.4 25.9 21.6 31.4 49.7 43.7 42.9 37.1 21.6 38.2 26.2 36.5 46.8 44.0 41.9 19.1 21.7 43.7 21.5 35.9 32.3 18.8 21.8 20.3 59.9 30.4 31.1 35.9 24.7 23.8 28.8 77.8 47.8 76.9 75.8 102.7 5.5 117.7 135.1 42.3 93.7 56.8 38.5 38.1 64.3 108.6 78.8 21.0 33.0 48.6 38.6 81.5 36.6 20.0 46.7 46.1 58.7 13.6 51.2 61.7 39.6 56.0 35.2 70.6 65.8 18.0 10.1 106.8 65.6 36.5 20.8 30.7 21.4 31.3 31.7 30.0 58.1 117.7 35.5 29.4 27.7 35.6 70.3 19.4 63.9 22.7 27.3 19.8 83.0 62.5 35.3 62.0 42.7 70.7 120.3 31.8 93.0 28.5 41.3 32.7 34.3 19.8 31.0 33.7 32.7 32.3 25.2 32.8 31.0 23.8 20.8 24.5 9.3 29.5 33.8 30.1 29.8 32.7 20.3 23.2 22.8 23.2 20.8 24.2 25.9 21.6 21.6 21.5 21.8 23.8 47.8 60.9 31.9 11.8 49.9 25.4 30.5 41.5 22.8 37.6 25.1 29.0 36.4 27.1 36.3 23.9 20.9 32.4 31.9 10.0 13.7 33.5 4.2 12.1 49.4 38.7 12.6 6.7 13.7 33.1 54.3 65.7 12.8 19.2 30.4 33.1 45.3 29.7 33.9 63.9 19.7 17.0 44.7 31.3 32.3 6.7 63.3 27.3 69.4 19.7 39.2 43.0 29.9 19.6 20.1 19.2 14.0 45.5 203.2 25.1 17.4 28.3 26.7 36.6 46.0 45.2 44.1 36.5 61.6 17.4 23.4 30.0 36.3 45.1 13.3 21.5 TXNDC5 "EndoPDI, ERp46, FLJ21353, FLJ90810, Hcc-2, MGC3178, PDIA15" ENSG00000239264 "Thioredoxin domain containing 5" Q8NBS9 6 7881517-7910788 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 42 "Plasma cells: 677.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "memory B-cell: 13.0;naive B-cell: 6.9;plasmacytoid DC: 26.7" "Group enriched" "Detected in many" 21 "B-cells: 13.0;dendritic cells: 26.7" "Cell line enhanced" "Detected in all" "RPMI-8226: 2833.2;U-266/84: 6053.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034677, HPA034678" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 6900000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA034677: AB_2674275, HPA034678: AB_2674276" "unprognostic (3.15e-1)" "unprognostic (1.09e-2)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" "unprognostic (6.95e-2)" "unprognostic (1.20e-2)" "unprognostic (6.07e-2)" "unprognostic (5.81e-2)" "unprognostic (3.56e-2)" "unprognostic (1.54e-1)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.05e-1)" "unprognostic (7.98e-2)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" 97.4 74.8 21.1 173.0 23.4 61.8 163.4 22.0 22.5 132.2 52.7 266.2 263.5 80.5 85.8 78.2 63.9 98.6 63.3 19.8 23.2 63.1 133.3 90.9 194.2 25.0 24.7 96.4 154.6 68.6 42.5 134.0 23.2 73.2 213.6 4.4 219.3 93.6 25.1 32.9 193.9 121.9 24.9 250.6 287.6 28.3 26.4 54.1 69.6 29.2 263.8 190.9 57.0 25.9 166.1 159.0 111.5 365.9 911.2 388.1 175.9 361.5 349.7 246.2 265.2 238.8 119.0 176.1 620.7 557.2 273.6 127.3 195.5 178.6 280.3 148.8 166.6 267.6 128.3 435.9 268.5 307.2 255.0 266.7 256.8 236.6 259.2 542.1 1334.0 109.7 170.5 1216.5 171.7 147.7 75.2 185.7 142.8 260.5 340.6 128.0 160.4 2833.2 201.1 149.6 168.7 90.5 462.4 280.2 209.4 514.9 143.5 133.9 369.7 280.5 194.2 243.0 386.5 1408.7 6053.9 305.0 144.7 191.7 392.2 0.0 0.4 0.0 0.9 0.7 0.7 13.0 0.2 0.7 1.0 6.9 0.2 0.4 0.0 0.0 0.1 26.7 0.9 0.5 21.1 23.4 22.0 22.5 19.8 23.2 25.0 24.7 23.2 24.9 26.4 25.9 1.3 0.0 4.8 0.0 14.6 0.9 0.2 0.4 3.4 0.0 1.8 1.3 0.2 0.0 2.0 0.0 0.0 0.9 5.6 1.2 0.0 9.0 0.1 1.1 6.9 3.2 4.9 11.2 0.0 10.7 1.9 4.1 6.1 2.3 1.3 0.6 3.9 4.9 1.5 0.0 0.0 15.9 0.0 0.8 0.7 0.0 0.0 1.3 3.6 0.0 1.8 0.1 0.0 0.0 0.0 9.5 1.5 0.4 677.7 0.4 3.2 0.5 1.7 0.5 6.6 0.5 4.2 0.1 0.1 3.9 0.1 1.2 2.0 0.2 5.8 0.2 TXNRD2 "SELZ, TR, TR3, TRXR2" ENSG00000184470 "Thioredoxin reductase 2" Q9NNW7 22 19875517-19941820 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2 OS: 139.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002007, HPA003323" Supported Approved Mitochondria,Cytosol NA NA 2800000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 47: Cytotrophoblasts - Unknown function" "Mitochondria, Cytosol" "CAB002007: , HPA003323: AB_1080396" "unprognostic (3.17e-2)" "unprognostic (8.72e-2)" "unprognostic (4.30e-1)" "unprognostic (9.71e-3)" "unprognostic (7.25e-2)" "unprognostic (6.35e-2)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (2.83e-1)" "unprognostic (4.94e-3)" "unprognostic (2.49e-1)" "prognostic favorable (1.10e-7)" "unprognostic (2.47e-1)" "unprognostic (5.99e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" 10.5 44.4 11.9 8.9 12.0 14.5 12.3 18.1 19.3 11.7 21.2 14.9 10.3 10.6 6.2 10.2 10.6 6.2 30.0 12.9 11.9 24.8 65.4 13.6 9.1 11.8 12.1 16.5 15.9 13.5 14.4 9.8 11.5 26.8 4.6 4.4 15.4 8.2 23.0 10.9 12.0 5.1 11.3 16.9 26.4 14.6 12.4 4.9 15.2 16.1 6.1 11.8 10.4 11.8 19.4 39.2 3.5 14.9 6.9 9.6 8.8 18.8 21.1 31.8 23.4 36.7 19.4 10.9 43.2 19.0 32.7 33.2 17.8 25.2 12.1 21.6 46.5 18.8 34.4 22.4 12.9 21.1 8.4 9.2 18.5 16.2 13.8 12.9 91.3 2.2 106.4 17.4 24.8 47.1 7.2 30.1 17.7 46.9 27.6 10.5 85.2 10.0 19.3 21.0 19.1 16.4 32.0 39.9 21.8 5.8 33.7 27.6 52.2 23.0 139.5 19.8 38.4 17.6 14.0 6.9 22.4 15.5 30.3 2.7 10.5 5.8 3.5 8.2 2.6 3.9 3.0 3.2 7.8 2.6 3.9 3.2 0.9 3.8 7.9 2.9 2.1 4.6 11.9 12.0 18.1 19.3 12.9 11.9 11.8 12.1 11.5 11.3 12.4 11.8 5.6 16.0 23.6 11.1 10.3 4.2 23.1 15.1 3.4 22.1 11.4 9.1 16.7 15.7 15.7 20.2 10.4 60.7 8.8 14.7 58.7 22.0 26.4 9.8 8.4 14.4 1.2 33.1 9.2 32.0 24.3 12.4 23.4 10.0 1.3 27.6 8.9 49.5 25.9 10.1 8.5 16.9 20.3 22.0 7.8 18.2 15.5 14.6 5.4 10.3 27.2 18.7 10.3 8.5 7.2 22.3 13.9 9.1 12.2 17.8 15.6 52.0 16.6 11.0 6.6 11.3 13.3 10.9 14.0 6.4 5.3 42.0 11.4 36.4 16.4 15.7 TYRP1 "b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP" ENSG00000107165 "Tyrosinase related protein 1" P17643 9 12685439-12710285 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 44.8;heart muscle: 59.9;skin 1: 145.0" "Cell type enriched" "Detected in some" 17 "Melanocytes: 2486.6" "Cancer enriched" "Detected in some" 262 "melanoma: 313.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 55 "SK-MEL-30: 1395.0" "Group enriched" "Detected in some" 5 "olfactory bulb: 4.6;thalamus: 1.8" "Low region specificity" "Detected in all" "HPA000937, CAB002520" Enhanced Approved Vesicles NA NA 51000 "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB002520: AB_564153, HPA000937: AB_1080437" "unprognostic (7.48e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-1)" "unprognostic (3.16e-3)" "unprognostic (8.10e-2)" "unprognostic (3.82e-3)" "unprognostic (1.53e-1)" "unprognostic (2.25e-3)" "unprognostic (4.46e-1)" "unprognostic (8.71e-2)" "unprognostic (6.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.68e-6)" "unprognostic (1.27e-1)" "unprognostic (5.99e-2)" "unprognostic (1.95e-2)" 0.3 0.0 0.1 0.6 0.4 0.2 4.9 0.3 0.9 0.0 44.8 2.2 5.0 0.0 1.2 10.0 0.2 4.5 59.9 2.6 0.0 16.2 0.0 3.7 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 5.3 2.7 1.3 0.0 4.8 145.0 4.7 1.8 0.1 0.0 2.1 1.1 0.3 0.0 0.0 7.5 0.0 1.1 0.4 1.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 25.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 4.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 1395.0 0.1 19.5 1.5 0.0 0.0 0.7 0.0 0.9 0.0 0.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.9 2.6 0.0 1.2 1.1 2.1 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 92.3 0.1 0.0 0.0 11.7 0.0 0.0 44.3 0.0 0.0 3.7 2.1 0.0 0.0 0.0 144.8 0.3 2.5 0.0 0.0 1.3 0.0 0.0 0.9 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 17.5 4.7 0.3 0.0 2486.6 0.0 0.0 15.9 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.6 0.0 0.0 1.4 0.7 0.7 0.0 16.8 0.0 0.5 0.0 0.0 0.2 UBAC2 "FLJ30548, PHGDHL1, RP11-178C10.1" ENSG00000134882 "UBA domain containing 2" Q8NBM4 13 99200774-99386504 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013448 Approved Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA013448: AB_1855301" "unprognostic (7.04e-2)" "unprognostic (1.19e-1)" "unprognostic (2.43e-1)" "unprognostic (7.30e-3)" "unprognostic (2.23e-1)" "unprognostic (2.79e-3)" "unprognostic (9.48e-3)" "unprognostic (6.50e-3)" "unprognostic (1.58e-1)" "unprognostic (6.95e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (6.44e-2)" "unprognostic (6.13e-3)" "unprognostic (3.33e-2)" "unprognostic (1.16e-1)" "unprognostic (6.08e-2)" "unprognostic (3.26e-2)" 15.3 13.3 9.0 18.2 9.3 19.6 20.0 7.3 9.2 21.3 9.9 21.5 30.7 19.9 17.9 28.6 27.6 22.6 27.3 10.1 8.4 21.9 27.7 16.9 25.4 10.9 9.6 19.1 17.4 30.0 2.7 29.4 8.8 18.4 22.9 7.6 25.8 17.3 39.0 30.6 23.3 19.7 11.6 20.8 17.7 26.2 12.6 29.3 30.0 38.9 27.3 23.9 8.6 8.8 51.8 26.8 22.4 33.9 52.2 62.8 56.3 25.9 73.3 40.3 36.4 29.2 108.7 19.9 43.8 34.8 27.0 49.2 28.8 41.1 22.0 33.8 33.7 37.2 16.9 22.5 48.7 48.2 28.1 45.9 54.9 24.6 71.0 54.6 38.8 39.6 31.1 13.3 31.6 14.3 32.1 15.3 32.6 104.0 27.0 27.6 24.9 15.2 32.7 29.6 25.2 40.3 21.0 67.8 41.4 39.4 41.5 148.7 30.3 21.9 19.0 20.1 29.5 16.3 12.0 6.6 42.9 71.9 38.3 64.6 53.7 41.9 61.3 57.3 87.3 48.1 53.8 62.6 46.2 55.2 73.6 74.5 48.8 84.6 57.5 57.3 40.2 88.1 9.0 9.3 7.3 9.2 10.1 8.4 10.9 9.6 8.8 11.6 12.6 8.8 28.7 6.4 19.1 58.8 45.3 27.1 26.0 41.7 40.5 27.3 31.2 24.3 23.8 21.5 29.4 23.9 27.1 111.6 48.5 37.3 23.5 44.1 26.0 24.5 21.7 26.4 8.4 31.3 110.9 34.9 84.6 31.6 19.4 21.9 22.2 34.3 17.9 29.1 48.5 32.0 103.0 30.1 40.7 39.1 121.4 22.0 35.1 88.4 30.2 81.5 35.7 48.8 69.0 82.0 73.3 29.0 32.6 50.8 11.7 48.7 48.0 22.6 31.6 21.2 32.9 24.7 32.1 66.2 35.1 31.7 33.1 132.4 66.0 54.4 39.1 34.4 UBALD1 FAM100A ENSG00000153443 "UBA like domain containing 1" Q8TB05 16 4608883-4615027 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 110.3;Late spermatids: 129.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 8.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066771 Approved Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA066771: AB_2685717" "unprognostic (7.09e-2)" "unprognostic (2.21e-2)" "unprognostic (1.55e-1)" "unprognostic (7.67e-3)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.54e-1)" "unprognostic (4.37e-3)" "unprognostic (2.63e-3)" "unprognostic (8.06e-2)" "unprognostic (1.95e-3)" "unprognostic (2.35e-1)" "unprognostic (3.99e-2)" "unprognostic (6.20e-2)" "unprognostic (1.35e-2)" 25.5 28.4 21.7 11.1 20.0 26.2 24.6 23.9 39.5 29.9 7.4 44.3 14.2 38.6 2.6 32.8 32.0 6.2 39.8 23.3 16.4 39.2 70.6 29.9 8.7 16.2 14.2 29.2 30.1 5.1 25.0 10.6 14.5 39.6 2.3 4.8 23.7 9.5 51.1 31.4 25.5 6.8 10.6 29.3 34.9 29.1 16.8 5.5 35.4 8.6 4.4 33.5 27.5 24.2 13.5 38.2 8.9 14.2 6.0 7.6 39.4 19.7 8.2 7.6 11.0 18.6 15.5 19.8 21.6 6.3 5.7 36.5 5.7 20.4 2.1 42.4 57.4 18.7 42.8 29.6 12.1 11.8 30.8 10.8 14.9 11.6 5.7 8.7 8.3 15.0 28.7 20.4 3.0 66.0 19.5 63.6 33.3 12.0 33.4 27.9 11.1 65.6 6.7 19.0 25.7 23.7 23.5 35.9 33.1 5.1 23.2 18.9 24.4 15.2 17.2 61.5 13.0 38.8 34.2 22.9 6.2 15.8 8.1 0.9 1.6 8.7 1.6 2.5 1.0 1.3 1.3 1.7 1.9 1.2 1.3 1.4 2.7 1.1 3.3 1.2 1.7 1.3 21.7 20.0 23.9 39.5 23.3 16.4 16.2 14.2 14.5 10.6 16.8 24.2 12.0 9.6 8.2 3.3 14.3 110.3 55.8 32.7 29.6 9.7 23.7 20.6 4.2 15.7 17.9 18.4 4.2 65.8 15.1 26.4 31.3 21.1 37.6 29.1 16.2 16.8 84.6 26.1 6.2 23.6 60.1 16.2 43.3 28.7 10.8 13.6 16.1 32.4 23.6 10.1 6.1 34.4 28.5 14.7 25.9 129.1 16.1 14.5 21.4 1.9 19.4 13.0 23.7 3.5 8.1 22.4 19.0 19.9 22.2 37.6 24.4 57.0 7.3 11.5 46.0 15.2 25.1 18.6 14.6 20.2 102.9 107.8 15.9 14.0 22.0 33.1 UBAP1 UBAP ENSG00000165006 "Ubiquitin associated protein 1" Q9NZ09 9 34179005-34252523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019804 Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "Vesicles, Plasma membrane" "HPA019804: AB_1858494" "unprognostic (1.83e-1)" "unprognostic (4.30e-2)" "unprognostic (1.29e-1)" "unprognostic (1.70e-1)" "unprognostic (3.54e-1)" "unprognostic (3.29e-2)" "unprognostic (1.67e-1)" "unprognostic (1.59e-1)" "unprognostic (2.01e-2)" "unprognostic (6.53e-2)" "unprognostic (1.25e-2)" "unprognostic (3.63e-1)" "prognostic favorable (7.49e-6)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (1.17e-1)" 40.7 55.5 46.4 24.5 47.1 131.5 35.8 48.0 53.4 45.0 46.4 38.5 22.3 34.0 25.5 69.7 33.9 30.4 38.2 45.6 48.2 34.8 53.1 42.5 23.8 48.5 48.5 40.9 28.0 34.4 25.6 29.3 49.4 30.4 24.8 44.8 29.6 30.6 110.0 39.5 26.3 35.2 46.3 28.2 33.6 47.8 49.9 31.6 25.6 71.7 32.7 38.0 45.8 48.2 56.7 31.7 35.2 38.4 63.6 39.3 29.8 44.4 61.6 48.4 65.6 34.3 23.0 39.3 19.5 66.5 41.1 28.3 49.2 69.5 46.4 57.1 22.3 35.1 65.4 35.5 57.8 39.3 44.8 48.7 113.0 57.5 75.0 73.4 54.4 37.9 27.4 38.0 45.7 23.7 36.5 55.0 38.2 38.8 45.9 32.6 24.8 22.8 104.2 36.9 19.9 28.1 49.0 50.2 22.5 31.1 24.6 38.5 39.2 24.7 38.0 37.4 41.5 18.9 25.3 41.0 49.5 31.5 74.2 26.8 50.9 66.6 38.0 45.2 65.8 26.8 38.1 40.0 47.1 23.2 36.3 29.8 120.2 50.1 41.0 26.7 52.9 55.0 46.4 47.1 48.0 53.4 45.6 48.2 48.5 48.5 49.4 46.3 49.9 48.2 21.6 67.3 26.0 44.4 22.4 46.9 66.3 20.4 45.5 15.8 27.9 23.1 13.1 20.0 33.5 7.3 25.0 33.2 21.6 25.8 19.6 34.8 77.5 56.9 37.2 21.4 16.1 50.7 33.1 40.1 35.4 31.2 44.4 90.0 25.9 15.4 17.5 25.3 22.0 6.7 42.9 18.5 30.5 21.4 39.8 62.9 29.2 38.2 24.9 26.2 23.1 26.0 13.4 38.7 35.4 44.3 23.0 42.5 25.0 47.9 22.5 21.0 22.5 10.9 19.7 44.0 32.5 51.0 22.9 54.6 59.0 89.6 28.6 20.8 18.8 70.9 UBAP2 "bA176F3.5, FLJ22435, KIAA1491" ENSG00000137073 "Ubiquitin associated protein 2" Q5T6F2 9 33921693-34048949 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021684 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" Cytosol "HPA021684: AB_2211887" "unprognostic (2.71e-1)" "unprognostic (1.99e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-2)" "unprognostic (1.69e-1)" "unprognostic (5.18e-2)" "prognostic unfavorable (3.45e-6)" "unprognostic (1.21e-1)" "unprognostic (4.64e-2)" "prognostic favorable (8.59e-4)" "unprognostic (1.75e-1)" "unprognostic (9.76e-3)" "prognostic favorable (1.95e-4)" "unprognostic (8.06e-2)" "unprognostic (2.39e-1)" "unprognostic (2.95e-1)" "unprognostic (8.77e-2)" 12.2 25.7 12.5 8.2 12.9 17.2 12.8 17.3 13.4 15.5 5.3 13.8 8.7 13.0 8.8 19.1 11.4 6.6 15.3 9.5 13.7 14.9 11.1 13.2 10.4 9.4 9.5 15.2 15.4 9.3 11.0 11.8 9.7 14.3 12.1 9.9 13.1 6.7 37.8 22.2 10.8 10.3 6.8 10.9 14.0 32.5 13.6 13.9 15.8 20.5 12.1 12.5 15.2 12.9 40.5 36.5 25.9 32.9 25.2 22.0 31.2 31.8 19.6 32.1 31.0 49.9 21.0 46.8 9.8 26.7 24.7 23.1 43.9 34.9 35.5 34.8 21.5 26.2 47.2 55.0 20.5 59.6 40.3 20.4 28.8 40.8 28.2 16.7 26.3 28.3 36.5 37.6 29.4 26.9 44.6 100.4 27.7 22.6 28.5 34.1 16.0 29.9 31.2 30.1 26.5 18.4 37.6 30.3 9.4 25.8 26.9 26.3 30.9 19.0 25.5 22.8 35.7 14.5 32.3 49.3 20.9 22.5 48.3 1.6 2.7 3.0 2.2 3.1 4.7 2.7 2.7 3.2 3.1 1.4 2.4 3.3 1.6 4.5 7.2 4.1 3.3 2.3 12.5 12.9 17.3 13.4 9.5 13.7 9.4 9.5 9.7 6.8 13.6 12.9 23.8 54.5 23.1 56.8 15.0 28.2 23.8 21.0 27.3 28.7 25.3 26.2 59.9 8.6 32.4 12.9 60.5 44.4 24.7 28.1 3.9 20.0 102.8 52.5 30.3 28.6 25.1 20.8 46.8 19.8 36.3 23.7 32.6 68.8 14.5 36.2 11.7 14.0 16.6 16.8 48.3 30.4 14.2 17.0 21.4 85.0 30.4 17.1 26.6 33.7 19.0 12.5 16.5 50.8 46.3 27.0 26.8 24.5 28.4 24.9 12.3 15.9 24.1 27.0 26.3 27.4 22.6 81.0 70.4 25.9 31.1 72.9 22.3 68.4 29.6 23.7 UBE2A "HHR6A, HR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574536-119591083 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 508.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (2.27e-3)" "prognostic favorable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 40.0 27.4 30.1 39.1 30.6 29.8 29.4 34.1 38.8 34.1 27.1 52.3 37.5 32.0 38.2 53.4 27.3 32.6 63.2 29.6 32.2 41.0 30.1 32.9 46.9 34.4 32.5 20.1 29.2 39.2 18.9 56.8 34.4 31.0 45.0 27.1 30.9 33.0 71.9 30.7 39.1 43.0 32.1 26.8 30.5 17.6 32.1 46.1 30.5 55.0 50.4 46.9 32.8 35.1 129.5 104.1 60.8 54.1 103.0 125.6 63.9 122.6 106.3 141.8 130.3 50.8 84.0 96.4 126.4 133.9 240.6 86.4 86.3 65.7 128.6 142.3 60.6 42.7 71.9 47.1 96.6 105.9 72.1 86.9 90.1 134.0 58.3 98.1 99.4 86.5 57.0 83.6 160.1 134.5 166.6 99.9 106.3 125.7 126.9 84.2 64.0 91.6 113.1 76.6 48.9 51.3 171.2 75.0 93.7 73.2 65.8 92.6 101.5 92.4 42.0 184.3 142.5 83.6 147.1 92.4 99.1 136.3 74.6 46.8 58.5 92.5 43.0 92.1 34.8 52.6 37.9 38.5 74.6 48.7 23.7 33.9 78.0 35.0 101.1 58.5 56.8 51.1 30.1 30.6 34.1 38.8 29.6 32.2 34.4 32.5 34.4 32.1 32.1 35.1 67.5 102.5 40.9 12.7 79.1 124.8 91.6 129.4 51.8 17.2 60.7 43.9 66.7 44.3 80.7 40.5 31.3 179.8 93.0 168.6 101.8 95.4 51.7 75.6 55.3 62.9 45.5 70.4 9.9 102.1 176.2 67.7 37.8 63.0 57.0 35.7 46.4 35.5 131.3 8.4 9.4 49.7 103.7 59.1 183.9 15.3 37.0 97.3 83.6 15.9 129.0 49.8 41.2 14.6 18.0 137.6 132.5 40.6 92.2 98.2 85.6 125.2 107.7 35.0 46.0 56.3 101.1 44.1 32.1 74.6 127.9 508.5 94.8 36.6 54.5 120.3 UBE2H "GID3, UBC8, UBCH" ENSG00000186591 "Ubiquitin conjugating enzyme E2 H" P62256 7 129830732-129952960 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 365.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003302 Approved Approved Mitochondria NA NA 21000 "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA003302: AB_1858526" "unprognostic (1.15e-1)" "unprognostic (5.85e-2)" "unprognostic (5.67e-3)" "unprognostic (2.76e-1)" "unprognostic (2.25e-1)" "unprognostic (3.08e-2)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (9.43e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (2.33e-5)" "unprognostic (1.13e-1)" "unprognostic (3.73e-2)" "unprognostic (2.37e-1)" "unprognostic (1.12e-1)" "unprognostic (3.58e-1)" "unprognostic (1.23e-1)" 46.8 64.7 43.0 29.1 44.2 42.3 34.4 46.4 49.1 44.7 58.7 42.3 23.4 44.3 37.6 49.9 44.6 44.6 98.2 42.1 45.4 42.1 44.2 38.8 31.8 48.7 43.4 41.7 84.3 49.2 29.4 52.5 45.0 36.1 26.0 42.0 39.3 41.5 69.3 31.2 24.4 49.2 41.8 28.6 34.6 36.4 45.8 37.4 45.0 60.6 39.8 40.1 33.7 47.8 82.6 43.8 58.5 56.1 126.1 107.5 86.5 72.0 97.8 45.8 51.1 22.9 92.5 34.0 87.4 76.6 123.8 62.5 46.2 81.6 59.5 40.9 22.6 11.5 63.5 28.6 98.3 23.6 36.8 146.7 106.9 61.3 99.7 106.3 89.7 36.3 27.5 104.1 71.5 29.9 31.1 26.1 80.0 60.5 49.8 24.4 27.8 77.2 95.9 106.5 20.3 59.6 68.3 164.7 43.8 166.0 17.1 27.2 89.1 51.7 24.2 72.2 76.5 83.5 65.6 58.5 102.1 28.9 49.7 2.2 1.4 3.4 2.8 1.2 3.8 2.3 2.8 2.6 1.3 4.5 3.6 3.8 4.8 0.9 1.5 2.3 4.4 1.3 43.0 44.2 46.4 49.1 42.1 45.4 48.7 43.4 45.0 41.8 45.8 47.8 69.9 41.7 51.8 87.1 43.1 145.8 187.5 65.7 59.7 65.1 83.7 49.4 102.9 44.3 69.3 71.7 60.5 116.3 56.7 38.6 41.1 66.0 93.5 225.7 91.2 81.4 59.1 100.0 97.1 70.9 67.1 65.2 43.8 365.8 14.7 53.9 45.3 73.1 41.8 43.7 116.9 35.3 54.9 40.3 69.8 44.0 44.1 52.0 48.0 89.0 26.2 87.4 51.5 113.1 108.5 118.3 33.6 78.6 60.5 227.6 27.6 49.7 95.3 35.6 13.1 65.9 69.0 46.5 22.5 78.6 153.7 200.4 49.2 79.7 26.6 274.3 UBE2O E2-230K ENSG00000175931 "Ubiquitin conjugating enzyme E2 O" Q9C0C9 17 76389456-76453152 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 54.7;Inhibitory neurons: 63.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023605 Uncertain Supported "Nucleoplasm,Nuclear bodies" No No 220000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Nuclear bodies" Nucleoplasm "HPA023605: AB_2671257" "unprognostic (8.75e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (8.68e-2)" "unprognostic (1.17e-1)" "unprognostic (3.22e-2)" "prognostic unfavorable (6.84e-8)" "unprognostic (3.54e-1)" "unprognostic (2.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (4.34e-9)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" 9.1 9.7 12.9 10.1 14.0 21.2 9.7 8.0 24.9 12.8 1.4 10.7 9.4 11.5 7.0 12.8 11.0 6.5 20.3 15.4 11.7 8.4 10.5 8.7 13.1 21.7 9.0 15.1 17.4 10.9 18.2 9.1 21.7 11.6 5.3 10.5 12.9 8.7 28.3 16.1 10.6 7.1 4.4 13.9 11.0 16.6 11.6 12.0 16.1 13.4 8.6 10.8 12.5 14.5 25.8 29.2 29.1 35.5 17.7 11.3 25.2 11.8 12.8 18.9 18.3 25.6 12.7 36.4 8.3 14.8 29.7 25.2 34.2 20.4 13.2 10.5 42.2 36.9 20.6 42.9 14.7 22.6 22.0 11.4 16.2 18.1 15.3 16.2 25.7 19.9 31.5 31.4 9.6 21.3 44.7 26.0 27.0 15.5 38.9 43.3 37.6 40.2 8.5 22.1 43.0 38.5 17.4 43.9 23.6 26.3 25.4 16.1 15.4 21.9 20.5 18.8 19.9 25.8 9.2 30.8 24.1 18.8 14.6 0.0 0.7 1.0 1.4 0.3 0.8 0.9 0.9 0.7 0.4 1.6 0.7 1.1 0.1 0.5 0.4 1.5 0.9 0.8 12.9 14.0 8.0 24.9 15.4 11.7 21.7 9.0 21.7 4.4 11.6 14.5 7.9 3.2 7.7 24.8 19.6 8.7 6.1 7.2 13.1 45.8 9.7 9.1 23.2 5.7 7.3 7.3 41.7 6.4 15.2 6.5 0.0 6.0 1.8 8.6 13.7 8.3 23.4 33.2 54.7 9.4 7.4 8.3 17.9 10.1 7.0 18.9 7.1 8.5 8.1 45.4 63.0 9.3 2.0 5.3 11.0 1.8 9.6 11.6 5.4 19.7 10.0 7.3 18.6 27.2 24.7 7.2 5.7 7.9 22.9 9.8 5.2 3.3 5.6 23.8 6.6 12.2 10.9 19.6 23.2 12.9 12.4 5.2 14.7 13.3 8.7 6.2 UBL7 "BMSC-UbP, MGC14421" ENSG00000138629 "Ubiquitin like 7" Q96S82 15 74445977-74461182 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 175.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040423, HPA041897" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA040423: AB_10673442, HPA041897: AB_2677732" "unprognostic (4.21e-2)" "prognostic favorable (6.37e-5)" "unprognostic (2.93e-3)" "unprognostic (5.56e-2)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "unprognostic (3.43e-2)" "unprognostic (1.29e-1)" "unprognostic (1.80e-1)" "unprognostic (6.71e-2)" "unprognostic (5.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.47e-3)" "unprognostic (8.94e-3)" "unprognostic (7.05e-2)" "unprognostic (2.75e-1)" "unprognostic (3.43e-2)" 33.8 38.4 27.0 13.5 28.9 15.9 32.9 26.7 35.0 34.0 23.9 48.1 15.0 36.8 15.4 37.8 30.3 10.6 67.9 29.4 26.9 38.1 32.0 29.7 21.4 28.2 27.3 31.1 44.7 25.0 30.3 15.6 29.2 36.4 16.5 13.1 34.2 16.3 114.6 54.3 36.9 18.4 25.5 48.2 43.5 55.8 25.9 27.3 37.0 37.8 29.6 38.7 33.1 29.0 18.7 20.3 31.6 42.3 32.4 42.1 21.8 29.8 36.0 37.6 46.6 24.7 26.4 27.2 31.1 35.9 48.6 29.4 88.4 40.4 36.5 36.0 55.6 35.8 32.2 45.3 31.7 22.4 29.1 32.9 35.5 32.1 43.0 32.3 32.0 60.8 30.9 39.3 39.3 26.2 28.1 35.3 75.7 31.2 24.6 29.4 25.0 60.5 32.6 21.2 31.1 61.8 28.8 26.8 40.1 44.1 28.6 36.7 18.8 34.6 20.4 17.4 37.5 39.8 82.1 30.5 22.7 40.3 30.6 32.9 51.6 59.7 35.1 58.5 33.7 50.5 35.3 37.1 70.6 55.3 33.9 40.6 65.3 55.5 55.5 151.5 65.6 52.1 27.0 28.9 26.7 35.0 29.4 26.9 28.2 27.3 29.2 25.5 25.9 29.0 17.3 32.1 18.2 3.9 35.4 15.8 24.1 35.6 26.7 5.8 24.9 23.9 29.9 18.6 20.0 14.7 8.4 71.1 36.8 25.5 58.7 37.3 75.3 12.7 13.0 20.7 23.4 45.8 5.7 34.7 66.9 20.7 22.4 13.5 19.0 21.5 22.5 16.3 41.9 5.0 3.8 26.9 20.3 38.3 31.4 175.8 24.5 31.4 21.4 5.6 82.6 18.2 23.7 4.0 4.5 29.5 27.6 21.1 51.6 19.5 48.9 44.6 16.1 9.0 19.7 13.5 50.5 59.2 31.1 29.8 25.1 68.4 23.0 19.6 28.0 25.2 UBR3 "DKFZp434P117, FLJ37422, KIAA2024, ZNF650" ENSG00000144357 "Ubiquitin protein ligase E3 component n-recognin 3" Q6ZT12 2 169827454-170084131 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 71.2;tongue: 87.1" "Cell type enhanced" "Detected in all" "Astrocytes: 162.6;Excitatory neurons: 305.1;Inhibitory neurons: 302.0;Oligodendrocyte precursor cells: 232.2;Oligodendrocytes: 288.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035390 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "HPA035390: AB_10670699" "unprognostic (1.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-2)" "unprognostic (1.27e-1)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (3.91e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (3.19e-2)" "unprognostic (5.56e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (2.18e-1)" 14.2 12.4 4.4 7.7 5.8 7.4 9.2 5.9 8.5 10.9 2.8 8.8 8.1 10.1 6.9 12.8 8.4 9.3 29.4 8.0 3.3 15.2 21.0 8.8 7.2 2.4 2.7 10.2 11.9 21.5 2.1 8.7 3.3 13.1 8.5 21.2 11.5 10.3 71.2 9.2 7.5 11.1 3.2 8.8 9.3 9.7 3.4 9.5 17.9 87.1 7.3 11.0 2.3 8.4 14.8 12.4 12.9 17.1 25.0 19.7 10.8 26.1 15.0 14.7 11.8 19.1 9.1 16.7 22.2 20.5 12.0 19.0 15.5 13.2 18.2 17.4 13.4 61.1 12.6 20.3 12.4 20.4 18.9 11.9 12.1 19.3 12.9 11.7 14.8 8.3 32.4 17.6 25.6 14.0 13.3 10.0 10.1 14.9 10.2 12.6 21.1 17.8 10.5 20.5 25.1 13.7 18.4 16.7 10.6 10.2 10.9 11.4 18.9 22.1 9.0 17.5 16.7 14.2 11.9 15.1 18.2 11.8 12.5 0.0 0.6 0.5 0.9 0.6 1.3 0.6 0.5 0.8 0.9 0.3 0.9 1.2 0.6 0.8 0.5 0.7 1.0 0.4 4.4 5.8 5.9 8.5 8.0 3.3 2.4 2.7 3.3 3.2 3.4 8.4 19.0 44.8 26.9 162.6 16.3 25.9 12.4 14.8 20.5 46.3 15.8 8.9 109.7 17.2 20.0 12.9 81.3 19.7 22.9 17.1 3.9 8.7 7.6 16.8 21.9 26.4 16.7 24.4 305.1 11.0 8.4 22.2 23.4 22.0 16.5 22.7 30.4 39.0 10.2 63.9 302.0 11.3 22.4 20.9 18.7 10.2 25.7 18.7 16.0 110.5 18.7 61.7 14.4 232.2 288.0 10.7 15.0 19.2 21.3 20.9 15.3 10.0 13.4 51.5 26.3 29.0 21.8 12.4 8.6 22.9 29.0 23.0 18.1 17.3 13.2 17.2 UBR4 "KIAA0462, KIAA1307, RBAF600, ZUBR1" ENSG00000127481 "Ubiquitin protein ligase E3 component n-recognin 4" Q5T4S7 1 19074510-19210266 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" "Calmodulin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 271.0;Suprabasal keratinocytes: 252.9;Urothelial cells: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013394, HPA021046" Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA 15000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Centrosome, Cytosol" "HPA013394: , HPA021046: AB_1858578" "unprognostic (1.37e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (2.02e-1)" "unprognostic (8.78e-2)" "unprognostic (9.77e-2)" "unprognostic (1.14e-3)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (9.14e-3)" "unprognostic (7.48e-2)" "unprognostic (2.53e-1)" "unprognostic (7.68e-3)" "unprognostic (4.30e-1)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.52e-1)" 56.2 62.8 48.2 23.0 46.0 79.8 49.8 38.7 48.4 57.4 47.6 69.6 20.9 61.7 35.7 55.4 52.3 29.6 58.7 45.8 46.0 74.7 82.7 71.9 25.7 51.5 46.4 75.3 53.5 35.5 70.7 27.5 54.9 67.2 22.7 44.6 48.0 27.0 129.1 161.9 59.7 26.0 35.2 62.8 70.6 105.3 45.9 34.6 56.5 45.0 25.7 90.0 59.2 44.7 61.4 60.7 53.5 39.7 97.6 50.0 46.2 46.5 48.8 49.5 44.7 97.2 51.3 36.6 42.3 61.7 43.3 40.8 42.3 46.3 46.0 30.6 37.5 83.8 63.3 64.1 68.6 51.9 53.4 45.0 57.9 100.8 96.3 48.1 54.9 63.7 58.5 32.9 47.6 43.6 24.7 62.9 43.5 124.3 33.6 34.0 41.7 31.0 44.7 35.2 37.7 37.4 55.0 31.1 39.9 48.6 21.7 40.4 85.9 57.4 36.1 69.0 52.8 38.8 25.2 41.5 39.3 79.3 50.3 39.8 28.7 4.7 4.9 5.9 4.2 7.4 4.4 2.9 14.2 4.0 3.9 3.7 15.4 4.4 2.1 6.5 3.4 8.3 48.2 46.0 38.7 48.4 45.8 46.0 51.5 46.4 54.9 35.2 45.9 44.7 28.1 35.3 37.6 85.5 30.3 271.0 124.6 28.9 28.5 57.5 22.1 23.9 19.1 37.1 30.4 31.3 152.2 24.7 34.2 31.6 13.7 41.3 21.4 39.8 32.0 30.8 17.5 48.4 58.9 40.9 17.0 32.2 44.9 50.4 19.6 32.9 31.1 94.1 63.2 79.1 61.8 29.2 12.2 43.0 48.7 28.7 30.7 46.4 49.8 34.7 64.4 28.8 21.6 51.8 44.5 61.0 16.7 35.7 26.4 59.1 57.9 135.6 39.1 48.5 19.7 28.3 30.1 44.8 21.0 28.0 252.9 33.9 32.7 34.5 20.1 236.5 UBXN4 "KIAA0242, UBXD2, UBXDC1" ENSG00000144224 "UBX domain protein 4" Q92575 2 135741734-135785056 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 863.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036325 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA036325: AB_10669788" "unprognostic (1.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (1.47e-1)" "unprognostic (1.54e-1)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (2.91e-1)" "unprognostic (5.40e-2)" "unprognostic (2.94e-2)" "unprognostic (2.63e-2)" "unprognostic (1.93e-1)" "unprognostic (1.83e-2)" "unprognostic (4.44e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-2)" "unprognostic (5.14e-3)" 51.9 55.6 33.3 58.4 38.3 65.4 57.4 37.4 38.0 62.3 44.7 57.1 69.8 56.0 71.1 44.4 49.0 57.2 44.3 31.5 33.8 64.2 93.8 47.2 59.5 40.2 36.8 52.6 73.4 83.5 19.6 63.0 40.1 64.6 60.2 85.6 71.8 47.8 55.1 56.0 67.9 43.9 35.9 55.7 64.6 57.7 33.7 76.6 76.1 52.7 59.8 60.5 25.1 47.6 136.2 34.6 85.1 66.2 106.9 107.0 95.5 106.6 106.3 87.0 77.4 65.3 91.8 84.0 149.4 105.1 46.6 98.3 50.7 68.4 103.5 115.5 62.8 80.5 60.7 98.6 99.4 85.2 70.7 81.6 66.6 86.7 85.8 118.2 110.5 66.2 74.4 116.1 95.3 64.1 109.9 61.3 64.3 70.6 70.9 87.9 100.5 146.5 112.2 97.7 77.4 50.2 97.2 64.1 64.4 77.1 68.0 78.2 101.8 78.4 40.1 82.5 58.4 108.7 72.2 76.2 99.0 59.3 75.5 62.9 35.8 59.1 46.5 42.3 42.6 45.9 42.5 42.5 35.8 42.6 41.4 41.0 73.7 48.4 52.2 56.6 52.3 35.9 33.3 38.3 37.4 38.0 31.5 33.8 40.2 36.8 40.1 35.9 33.7 47.6 178.1 208.3 171.4 56.2 177.4 175.1 283.0 318.5 160.5 172.3 164.1 153.3 150.8 134.4 264.1 126.9 223.1 238.2 140.8 168.9 90.1 254.6 863.9 209.3 223.1 151.7 186.6 129.8 85.2 195.8 214.0 197.4 129.5 240.6 176.9 151.5 113.2 225.7 138.8 97.6 78.4 246.9 183.1 88.6 125.2 325.1 172.7 139.9 92.5 60.9 158.8 162.2 122.6 71.9 105.3 190.7 166.7 143.7 300.3 344.1 183.0 156.8 286.7 349.8 105.2 159.3 173.9 446.1 248.4 176.1 183.6 379.4 171.6 271.6 186.0 303.7 UBXN8 "D8S2298E, REP8, UBXD6" ENSG00000104691 "UBX domain protein 8" O00124 8 30729131-30767006 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 79.9" "Group enriched" "Detected in many" 5 "Early spermatids: 167.4;Granulosa cells: 191.2;Hepatocytes: 65.7;Late spermatids: 180.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017725, HPA077538" Enhanced Supported "Nucleoplasm,Nucleoli,Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "Nucleoplasm, Nucleoli" "HPA017725: AB_1847462, HPA077538: AB_2686844" "unprognostic (3.00e-2)" "unprognostic (2.30e-1)" "prognostic favorable (6.13e-4)" "unprognostic (7.71e-2)" "unprognostic (2.24e-1)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (1.84e-2)" "unprognostic (1.90e-1)" "unprognostic (5.13e-2)" "unprognostic (1.58e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.25e-5)" "unprognostic (2.49e-1)" "unprognostic (1.96e-1)" "unprognostic (1.51e-1)" "unprognostic (6.88e-2)" 10.2 17.3 17.0 7.1 12.0 8.8 14.1 12.2 16.1 10.4 0.0 12.5 13.1 10.4 49.9 10.7 13.2 13.5 4.9 13.3 5.4 22.1 44.1 8.7 8.1 10.3 4.2 79.9 33.0 20.5 2.8 15.6 10.6 16.3 16.3 11.6 8.5 18.6 3.7 16.9 12.1 10.8 1.7 11.1 12.4 37.1 9.2 14.3 25.9 5.4 9.7 10.4 3.3 12.7 16.4 17.0 11.7 12.2 17.9 25.2 14.3 29.5 17.2 15.2 19.6 27.6 6.1 26.8 23.2 24.5 25.9 14.8 3.1 16.8 24.6 23.9 27.2 77.0 14.0 33.0 27.3 18.1 41.8 20.2 17.4 25.6 12.7 13.6 14.1 12.8 71.9 21.8 35.5 16.1 18.6 14.6 22.9 52.2 12.9 21.4 10.9 18.3 27.7 22.4 6.4 17.7 8.3 26.0 52.1 14.1 16.8 30.4 17.3 17.0 7.8 8.2 28.3 8.8 29.2 19.7 15.0 29.0 25.5 0.0 4.6 0.6 6.2 4.9 5.4 4.7 3.3 5.8 5.2 1.9 3.0 5.5 0.8 2.8 2.4 6.5 3.2 2.7 17.0 12.0 12.2 16.1 13.3 5.4 10.3 4.2 10.6 1.7 9.2 12.7 20.5 3.2 8.2 5.5 5.2 0.0 5.4 0.0 8.0 2.5 7.5 7.6 4.3 17.2 3.1 14.7 20.9 23.8 10.7 7.5 7.9 9.7 167.4 9.1 18.6 12.4 8.5 12.8 5.4 5.3 20.2 22.8 9.7 11.3 14.0 191.2 21.4 65.7 22.0 11.8 7.8 9.7 0.0 16.7 0.0 180.4 14.3 8.9 0.0 6.5 11.6 8.1 12.3 4.5 16.3 3.1 6.0 9.8 6.7 4.9 6.9 25.4 0.7 2.2 6.6 8.7 10.4 16.1 24.2 13.0 0.0 15.2 6.6 27.1 11.8 4.4 UCHL1 "PARK5, PGP9.5, Uch-L1" ENSG00000154277 "Ubiquitin C-terminal hydrolase L1" P09936 4 41256413-41268455 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 692.7;pituitary gland: 285.4" "Cell type enhanced" "Detected in many" "Collecting duct cells: 115.8;Distal tubular cells: 258.2;Excitatory neurons: 147.1;Horizontal cells: 146.4;Inhibitory neurons: 118.4;Spermatogonia: 88.4" "Cancer enhanced" "Detected in all" "glioma: 129.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1142.2;SCLC-21H: 1160.6;U-251 MG: 1162.6;U-266/84: 1138.4;U-87 MG: 1209.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002580, HPA005993, CAB079024" Enhanced Supported Supported Nucleoplasm,Cytosol NA NA 500000 "Cluster 43: B-cells - Humoral immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "CAB002580: AB_563981, CAB079024: , HPA005993: AB_1858560" "unprognostic (1.54e-1)" "unprognostic (1.96e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.08e-5)" "unprognostic (2.34e-1)" "unprognostic (1.98e-1)" "unprognostic (6.28e-3)" "unprognostic (1.09e-2)" "unprognostic (4.31e-2)" "unprognostic (8.77e-3)" "unprognostic (3.56e-3)" "unprognostic (3.70e-2)" "unprognostic (1.82e-3)" "unprognostic (1.24e-2)" "unprognostic (7.12e-3)" "unprognostic (2.10e-2)" "prognostic unfavorable (1.93e-4)" 30.1 104.4 211.4 19.2 188.8 0.6 13.6 83.4 342.7 18.9 0.0 49.0 9.0 13.2 3.3 3.3 9.7 12.3 26.9 229.7 692.7 62.7 1.6 8.2 12.9 255.7 205.2 35.6 11.6 0.6 285.4 2.5 446.7 12.3 6.9 38.3 3.7 5.8 27.5 4.7 18.9 9.2 122.2 2.7 14.5 16.5 150.3 4.1 9.8 7.7 7.3 31.7 29.1 231.2 3.3 712.8 146.8 0.4 18.9 19.7 0.4 681.4 352.8 236.0 243.4 149.0 0.9 0.0 1142.2 384.4 356.7 1.1 262.8 0.6 116.4 1.5 97.0 0.0 6.9 0.2 529.3 0.1 1.2 127.4 3.0 197.9 0.0 413.7 2.0 0.0 0.0 2.3 122.6 0.6 1.0 12.3 435.3 0.0 714.1 0.1 297.2 0.7 386.3 0.3 1160.6 765.7 5.1 2.8 1.8 165.4 0.8 5.0 3.3 16.8 5.2 0.4 1162.6 583.1 1138.4 3.1 1209.3 1.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 211.4 188.8 83.4 342.7 229.7 692.7 255.7 205.2 446.7 122.2 150.3 231.2 0.8 0.0 3.1 29.0 2.1 1.7 1.1 1.5 1.2 25.6 0.3 0.6 3.1 0.0 3.5 115.8 8.4 3.6 0.0 0.1 258.2 4.3 3.5 0.9 9.8 3.9 4.2 0.8 147.1 0.8 0.8 35.4 1.1 0.5 2.5 46.3 8.9 0.6 4.7 146.4 118.4 0.0 4.1 0.6 3.4 6.0 37.0 2.3 3.6 35.6 0.6 21.6 0.0 55.8 54.6 3.0 0.0 17.3 9.2 3.7 0.0 17.1 7.4 61.3 0.0 3.6 35.7 10.4 88.4 0.3 1.6 1.5 1.3 20.0 0.2 1.0 UCMA "C10orf49, GRP" ENSG00000165623 "Upper zone of growth plate and cartilage matrix associated" Q8WVF2 10 13221766-13234374 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;ovary: 1.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.7" "Group enriched" "Detected in some" 6 "amygdala: 1.2;basal ganglia: 2.2;cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046718 Uncertain "Secreted to extracellular matrix" NA NA 20000 "Cluster 10: Brain - Neuronal signaling" "Cluster 52: Non-specific - Transcription" "HPA046718: AB_2679771" "unprognostic (4.25e-1)" 0.0 0.0 1.2 0.0 2.2 0.0 0.0 0.2 1.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.2 1.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.2 0.2 1.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 UCN "UI, UROC" ENSG00000163794 Urocortin P55089 2 27307400-27308445 "Predicted secreted proteins" Hearing Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.2" "Cell type enhanced" "Detected in many" "Astrocytes: 7.8;Excitatory neurons: 6.5;Inhibitory neurons: 5.5;Oligodendrocytes: 6.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 19.4" "Low region specificity" "Detected in many" CAB010911 Approved Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 133000 "Cluster 40: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "CAB010911: AB_261834" "unprognostic (7.35e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.42e-2)" "unprognostic (5.08e-2)" "unprognostic (7.72e-2)" "unprognostic (5.69e-3)" "unprognostic (2.66e-1)" "unprognostic (2.48e-1)" "unprognostic (1.15e-1)" "unprognostic (3.80e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.84e-7)" "unprognostic (4.84e-2)" "unprognostic (3.87e-2)" "unprognostic (2.98e-1)" "unprognostic (1.11e-1)" 1.5 5.1 8.6 0.6 8.2 1.1 1.5 8.4 13.5 3.3 4.2 2.4 0.3 2.4 0.5 0.9 3.0 0.8 4.2 8.0 7.3 2.0 5.9 1.9 0.7 9.7 18.2 2.9 2.3 0.0 4.3 1.0 14.9 3.0 0.0 0.9 0.9 0.3 4.8 1.3 1.9 0.4 7.1 2.9 1.3 2.8 8.4 0.6 1.7 0.4 0.2 2.8 1.7 10.1 1.2 2.7 0.4 0.7 1.2 1.0 5.1 0.4 1.0 0.4 0.4 0.2 2.1 1.1 0.6 0.4 1.2 0.4 0.4 0.3 0.0 3.4 4.4 2.4 2.0 2.2 2.9 0.2 2.6 1.5 2.0 0.2 2.4 2.6 0.0 2.0 2.4 1.9 0.1 2.0 1.3 7.2 4.4 0.1 2.8 3.5 2.3 1.5 0.1 0.5 0.7 2.3 1.1 0.1 6.4 0.3 1.1 3.2 0.2 0.8 4.8 1.4 1.9 19.4 2.3 0.7 3.7 5.7 1.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.0 8.6 8.2 8.4 13.5 8.0 7.3 9.7 18.2 14.9 7.1 8.4 10.1 0.8 0.0 0.5 7.8 1.1 0.5 0.3 0.3 0.0 2.3 1.8 1.0 0.4 4.3 0.2 0.0 0.0 0.6 3.2 0.5 0.0 0.7 0.6 0.5 0.9 0.8 0.0 2.7 6.5 3.8 0.6 0.7 0.0 0.5 0.0 1.2 1.1 1.1 0.7 1.7 5.5 0.3 2.0 1.3 2.4 0.4 1.5 0.9 0.0 3.7 0.9 1.8 0.0 2.5 6.0 0.6 1.1 0.7 0.1 0.7 1.1 0.5 0.5 3.5 0.0 1.5 1.2 1.1 0.6 0.0 0.0 0.8 0.8 0.4 0.5 0.1 UCN2 "SRP, UCN-II, UCNI, URP" ENSG00000145040 "Urocortin 2" Q96RP3 3 48561718-48563781 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 13.1;vagina: 4.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.9;Basal respiratory cells: 1.4" "Cancer enriched" "Detected in many" 5 "melanoma: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 18.8;hTCEpi: 27.3;hTEC/SVTERT24-B: 21.5;SiHa: 19.1;U-251 MG: 20.7;WM-115: 55.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA066841 Uncertain Approved Vesicles "Secreted to blood" NA NA 98600 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA066841: AB_2685735" "unprognostic (7.98e-2)" "unprognostic (1.35e-1)" "unprognostic (4.80e-2)" "unprognostic (1.96e-2)" "unprognostic (2.39e-2)" "unprognostic (4.26e-2)" "unprognostic (1.92e-3)" "unprognostic (2.02e-3)" "unprognostic (1.62e-1)" "unprognostic (2.93e-3)" "unprognostic (2.52e-3)" "unprognostic (1.09e-1)" "unprognostic (3.34e-14)" "unprognostic (4.39e-2)" "unprognostic (2.75e-1)" "unprognostic (1.36e-1)" "unprognostic (2.88e-2)" 0.1 0.0 0.2 0.3 0.1 0.1 0.4 0.3 0.4 2.3 0.1 0.2 0.1 1.2 0.7 3.4 0.2 0.4 0.3 0.2 0.4 1.4 0.0 0.2 0.0 0.3 0.3 0.2 0.0 0.0 0.3 0.2 0.3 3.1 0.0 0.0 1.6 0.4 0.3 13.1 0.2 0.2 0.2 0.7 0.2 1.4 0.3 0.0 0.0 0.0 0.1 0.5 4.5 0.2 0.0 3.1 0.5 0.1 1.8 1.1 2.6 9.7 12.1 5.9 4.4 0.0 0.0 0.0 0.4 2.3 7.0 1.9 0.0 11.6 3.2 9.2 0.2 0.2 18.8 1.5 2.0 0.0 0.5 1.3 27.3 21.5 4.3 4.1 0.0 0.2 0.0 0.2 0.9 0.0 0.0 1.8 0.8 0.0 0.2 0.2 0.3 0.0 1.8 0.0 0.0 0.0 19.1 0.0 14.5 1.7 0.3 0.4 0.0 2.6 1.8 0.3 20.7 0.1 0.3 0.0 8.8 0.1 55.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.2 0.4 0.3 0.3 0.3 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 2.9 0.3 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 UCN3 "SPC, UCNIII" ENSG00000178473 "Urocortin 3" Q969E3 10 5364966-5374692 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.8;pancreas: 5.8;stomach 1: 3.4" "Cell type enriched" "Detected in some" 29 "Enteroendocrine cells: 242.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 15.4" "Region enhanced" "Detected in some" "medulla oblongata: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "SCLC-21H: 1.2" "Region enhanced" "Detected in some" "hypothalamus: 5.1" HPA038281 Uncertain "Secreted to blood" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA038281: AB_10672408" "unprognostic (2.00e-2)" "unprognostic (2.31e-1)" "unprognostic (1.60e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-3)" "unprognostic (8.42e-2)" "unprognostic (3.55e-2)" "unprognostic (2.91e-2)" 0.0 0.8 1.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 2.3 8.8 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.8 0.7 0.0 0.6 0.0 1.9 0.5 0.0 5.8 0.0 2.7 0.1 0.1 0.3 2.3 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.1 0.0 0.8 1.9 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.1 242.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 0.0 0.0 0.3 0.6 2.9 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.2 UGGT1 "HUGT1, UGCGL1" ENSG00000136731 "UDP-glucose glycoprotein glucosyltransferase 1" Q9NYU2 2 128091200-128195677 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012761, HPA015127" Enhanced Uncertain Cytosol NA NA 4000000 "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 52: Non-specific - Transcription" Cytosol "HPA012761: AB_1858597, HPA015127: AB_1858596" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (6.14e-2)" "unprognostic (1.87e-1)" "unprognostic (4.63e-2)" "unprognostic (6.45e-2)" "unprognostic (7.03e-3)" "unprognostic (3.13e-2)" "unprognostic (3.02e-2)" "unprognostic (1.05e-1)" "unprognostic (4.09e-3)" "unprognostic (7.05e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (3.86e-1)" "unprognostic (1.50e-1)" "unprognostic (2.23e-2)" "unprognostic (8.38e-3)" 8.1 8.5 4.2 13.7 4.6 21.8 7.6 4.8 6.5 9.1 5.0 12.4 9.0 7.3 19.9 8.0 6.5 6.5 8.0 4.3 4.6 8.2 14.9 8.4 12.3 4.7 4.4 5.1 14.8 8.7 6.5 8.7 5.0 8.7 10.0 9.7 8.6 6.2 13.2 8.8 10.2 6.2 4.0 9.4 10.7 6.4 4.8 11.7 10.4 13.0 12.6 7.5 6.6 5.6 34.8 11.8 22.0 47.6 28.0 22.3 34.3 39.4 16.7 12.7 11.3 26.0 24.9 49.4 15.4 28.3 11.3 25.3 16.8 16.8 25.5 31.5 8.2 43.4 14.9 82.3 28.0 58.6 25.9 16.3 13.0 25.4 23.0 25.0 29.8 19.8 28.4 25.6 26.9 24.4 23.5 33.5 39.5 24.0 12.4 19.2 21.3 20.9 23.8 25.2 11.7 17.4 27.3 36.0 24.4 22.5 14.4 40.2 43.1 34.6 24.4 20.1 28.4 27.3 40.4 22.3 29.3 31.4 32.6 3.8 2.5 2.5 2.3 2.5 2.3 1.6 1.9 2.1 1.9 3.3 1.6 2.3 3.7 1.9 2.5 3.1 1.6 1.4 4.2 4.6 4.8 6.5 4.3 4.6 4.7 4.4 5.0 4.0 4.8 5.6 14.6 35.3 24.7 24.8 14.3 8.2 6.4 11.1 5.7 19.8 11.2 7.1 16.7 12.8 20.7 3.7 22.9 10.5 22.1 21.5 1.9 14.0 9.2 18.4 27.7 16.5 22.8 31.5 40.6 19.5 20.1 16.6 21.9 22.2 11.4 20.8 17.9 39.7 16.6 20.2 37.6 21.9 8.2 25.4 16.4 2.3 14.9 20.0 14.2 32.8 26.0 7.5 15.5 31.2 46.5 19.4 10.4 13.5 31.5 13.3 25.3 8.4 12.7 20.2 6.6 18.5 13.3 10.0 8.5 9.4 10.7 10.8 18.9 16.0 22.8 10.1 UGGT2 "FLJ10873, FLJ11485, HUGT2, MGC117360, MGC150689, MGC87276, UGCGL2" ENSG00000102595 "UDP-glucose glycoprotein glucosyltransferase 2" Q9NYU1 13 95801580-96053482 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 112.0;Excitatory neurons: 215.1;Inhibitory neurons: 169.6;Oligodendrocyte precursor cells: 209.1;Oligodendrocytes: 207.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.9;eosinophil: 2.6;intermediate monocyte: 6.2;myeloid DC: 3.6;non-classical monocyte: 6.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047955 Uncertain "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA047955: AB_2680222" "unprognostic (5.32e-2)" "unprognostic (2.56e-1)" "unprognostic (2.51e-2)" "unprognostic (1.83e-1)" "unprognostic (9.33e-2)" "unprognostic (8.70e-2)" "prognostic unfavorable (9.99e-4)" "prognostic unfavorable (5.47e-4)" "unprognostic (1.55e-1)" "unprognostic (9.21e-2)" "unprognostic (7.75e-3)" "unprognostic (6.27e-2)" "unprognostic (5.65e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (9.61e-2)" "unprognostic (1.61e-2)" 11.8 6.9 5.1 5.1 6.3 3.8 9.3 1.1 9.1 8.2 6.3 6.9 5.4 10.3 16.0 4.0 7.8 6.0 8.7 5.7 4.3 7.5 8.3 6.7 3.0 3.6 2.9 7.8 10.7 7.6 8.8 11.2 3.5 7.4 6.2 7.8 8.0 7.3 4.0 4.8 4.6 10.0 2.8 3.8 7.8 12.0 3.5 1.2 11.4 4.3 2.6 8.2 6.0 8.1 20.3 9.6 19.8 10.2 32.5 34.4 16.0 32.5 25.2 15.6 26.6 14.6 17.2 7.0 11.8 22.0 11.4 12.4 7.0 7.0 22.9 0.2 8.6 9.0 19.1 9.6 19.0 25.4 20.9 20.6 7.4 5.9 18.7 28.8 14.2 0.1 5.8 11.5 22.1 6.0 0.2 10.9 8.4 15.1 5.8 0.1 14.4 10.5 13.6 19.4 4.1 15.3 18.6 18.4 13.2 26.9 16.4 12.1 23.1 15.7 10.2 17.6 17.1 16.1 8.3 8.8 40.9 13.3 21.2 0.4 5.9 2.6 0.1 6.2 0.0 1.2 0.1 0.1 3.6 0.4 0.1 0.1 0.4 1.1 6.0 0.3 0.0 1.9 5.1 6.3 1.1 9.1 5.7 4.3 3.6 2.9 3.5 2.8 3.5 8.1 22.2 16.0 19.9 112.0 3.9 4.0 10.3 10.6 10.2 19.5 11.0 13.1 13.1 7.2 16.3 14.7 31.3 18.3 0.5 5.8 0.0 13.9 44.7 13.2 34.3 17.7 4.8 7.8 215.1 18.9 17.3 32.4 12.2 20.9 18.3 22.4 12.8 8.6 7.5 18.5 169.6 7.1 8.2 7.1 11.9 15.4 22.1 8.5 3.6 76.8 6.8 11.8 0.0 209.1 207.3 18.6 5.2 16.6 9.8 9.9 4.0 5.6 15.1 17.1 32.9 28.2 32.3 38.1 26.3 8.0 3.1 13.8 1.6 19.5 7.8 7.5 UGT1A10 UGT1J ENSG00000242515 "UDP glucuronosyltransferase family 1 member A10" Q9HAW8 2 233636454-233773305 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 22.0;intestine: 79.5;stomach 1: 32.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 1.8;Gastric mucus-secreting cells: 3.6;Intestinal goblet cells: 1.0;Paneth cells: 1.4;Proximal enterocytes: 3.9;Squamous epithelial cells: 4.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 143 "RT4: 523.3" "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (9.33e-2)" "unprognostic (7.64e-2)" "unprognostic (2.45e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.49e-10)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (3.59e-3)" 0.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 49.5 79.5 0.1 0.0 14.6 0.0 22.0 0.0 0.0 0.0 0.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 36.5 0.0 0.9 0.0 0.0 0.9 53.1 1.9 0.0 0.0 32.7 1.5 0.0 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 1.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 523.3 0.0 0.1 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.3 UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" P0DTE4 4 69588417-69653249 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 3.6;kidney: 2.3;liver: 3.6;pituitary gland: 5.6" "Cell type enriched" "Detected in some" 18 "Proximal tubular cells: 107.9" "Cancer enhanced" "Detected in some" "liver cancer: 0.7;lung cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017261, HPA045108" Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA017261: AB_10963582, HPA045108: AB_2679218" "unprognostic (3.93e-3)" "unprognostic (5.62e-1)" "unprognostic (1.28e-4)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 3.7 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 UGT2B28 ENSG00000135226 "UDP glucuronosyltransferase family 2 member B28" Q9BY64 4 69280475-69295050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "breast: 198.5" "Cell type enriched" "Detected in single" 16 "Cholangiocytes: 10.0" "Cancer enriched" "Detected in single" 8 "breast cancer: 1.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Group enriched" "Detected in some" 10 "Daudi: 2.9;NB-4: 2.7" HPA045108 Uncertain "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA045108: AB_2679218" "unprognostic (1.81e-1)" "unprognostic (1.40e-1)" "unprognostic (7.20e-3)" "unprognostic (1.51e-2)" "unprognostic (4.37e-5)" "unprognostic (9.79e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 198.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 107 "liver: 1273.7" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 883.5" "Cancer enriched" "Detected in some" 96 "liver cancer: 351.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "RH-30: 4.6" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "CAB033260: AB_2241496, HPA045108: AB_2679218" "unprognostic (7.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-2)" "unprognostic (1.47e-1)" "unprognostic (9.43e-3)" "unprognostic (3.52e-1)" 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 11.9 0.0 0.0 1.3 1273.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.4 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 10.7 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 11.7 883.5 0.1 0.0 0.1 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "kidney: 1299.8;liver: 1612.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 150.6;Glandular and luminal cells: 234.7;Hepatocytes: 550.8;Proximal tubular cells: 1249.5" "Group enriched" "Detected in many" 7 "liver cancer: 116.4;renal cancer: 101.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 310.8" HPA045108 Uncertain NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA045108: AB_2679218" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic favorable (7.65e-5)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" "prognostic favorable (3.79e-4)" "unprognostic (1.08e-2)" "unprognostic (2.55e-1)" "unprognostic (6.23e-3)" "prognostic favorable (5.38e-4)" 0.2 0.0 0.0 0.3 0.0 0.0 2.3 0.0 0.0 32.0 0.0 3.8 68.7 8.9 24.2 0.2 49.9 10.4 0.0 0.0 0.0 1299.8 1612.1 0.4 0.0 0.0 0.0 0.1 9.9 0.0 0.0 0.1 0.0 0.3 6.9 0.0 3.6 27.5 0.0 0.3 66.6 0.3 0.0 0.0 0.9 0.1 0.0 0.9 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.3 0.0 0.0 77.6 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 41.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.0 0.1 0.6 0.1 310.8 2.7 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 43.2 0.0 0.0 0.0 0.2 0.3 0.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.6 1.6 0.0 0.0 1.2 0.6 0.1 38.6 2.1 125.0 0.0 0.0 0.0 5.7 97.8 6.6 0.3 150.6 14.0 1.0 3.5 2.7 0.4 10.6 0.0 0.1 0.0 234.7 0.0 0.0 8.9 550.8 0.1 0.0 0.3 37.3 0.0 13.8 0.0 0.0 1.8 7.6 3.6 0.0 0.0 0.0 0.0 1.5 0.4 13.0 10.7 0.0 0.0 0.6 70.6 1249.5 0.5 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 6.3 0.1 5.9 2.3 UGT3A1 FLJ34658 ENSG00000145626 "UDP glycosyltransferase family 3 member A1" Q6NUS8 5 35951006-36001028 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 51.1;liver: 58.0" "Cell type enhanced" "Detected in some" "Collecting duct cells: 49.7;Early spermatids: 125.9;Hepatocytes: 72.1;Late spermatids: 24.5;Proximal tubular cells: 87.0" "Group enriched" "Detected in some" 15 "liver cancer: 6.7;renal cancer: 4.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 42 "RH-30: 28.2" "HPA047697, HPA056290" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "HPA047697: AB_2680122, HPA056290: AB_2683088" "unprognostic (2.41e-3)" "unprognostic (4.47e-1)" "unprognostic (4.04e-1)" "unprognostic (4.62e-1)" "unprognostic (1.42e-2)" "unprognostic (6.05e-2)" "unprognostic (9.14e-2)" "unprognostic (1.76e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 51.1 58.0 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.2 0.0 0.1 0.3 0.0 0.7 0.1 0.2 3.0 0.0 6.7 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 49.7 0.0 0.0 0.0 0.0 3.9 0.0 125.9 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 72.1 0.1 0.0 0.3 0.7 0.0 2.6 0.0 24.5 0.9 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.5 0.4 0.0 0.0 3.8 87.0 0.0 0.2 6.6 0.0 0.0 4.4 0.8 0.0 0.0 0.0 0.5 0.0 1.8 0.1 UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035021-36071358 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 14.7;skin 1: 10.3" "Group enriched" "Detected in some" 4 "Collecting duct cells: 3.7;Early spermatids: 4.4;Late spermatids: 8.2;Proximal tubular cells: 3.8" "Cancer enriched" "Detected in some" 5 "testis cancer: 4.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.8;JURKAT: 6.3;MOLT-4: 12.4;REH: 29.9;SuSa: 11.8;T-47d: 7.2;THP-1: 18.0" "Low region specificity" "Detected in many" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: AB_2684031" "unprognostic (1.83e-4)" "unprognostic (9.94e-2)" "unprognostic (8.87e-2)" "unprognostic (4.82e-4)" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (1.56e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.36e-3)" "unprognostic (6.65e-2)" "unprognostic (7.52e-2)" "unprognostic (7.38e-2)" "unprognostic (4.52e-3)" 0.0 0.8 0.0 0.0 0.0 6.5 1.1 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 2.6 0.6 0.0 0.0 1.0 1.1 0.0 0.0 0.1 0.9 0.2 1.2 0.4 0.0 0.1 0.1 0.0 0.1 10.3 0.0 0.0 0.1 1.2 0.1 2.9 0.6 14.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.6 1.8 0.0 0.1 0.0 0.0 0.3 0.4 0.0 1.3 0.0 0.5 6.8 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 12.4 0.0 5.3 0.0 0.0 29.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 7.2 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 1.0 1.1 1.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 3.7 0.0 0.2 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 1.1 8.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.1 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 UGT8 CGT ENSG00000174607 "UDP glycosyltransferase 8" Q16880 4 114598770-114678225 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 266.4" "Cell type enriched" "Detected in many" 8 "Oligodendrocytes: 821.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 6.9;naive B-cell: 10.7" "Lineage enriched" "Detected in single" 12 "B-cells: 10.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 58.4;OE19: 123.7;RPTEC TERT1: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014405, HPA065785" Enhanced Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA014405: AB_1858606, HPA065785: AB_2685559" "unprognostic (7.38e-3)" "unprognostic (2.07e-1)" "unprognostic (1.25e-2)" "unprognostic (2.38e-1)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "unprognostic (7.78e-2)" "unprognostic (1.56e-3)" "unprognostic (4.49e-2)" "unprognostic (2.76e-1)" "prognostic favorable (8.55e-5)" "unprognostic (2.80e-1)" "unprognostic (1.78e-2)" "unprognostic (7.53e-2)" "unprognostic (1.49e-1)" 0.6 0.6 58.6 4.6 153.7 1.1 4.6 166.2 94.5 7.0 9.7 26.8 30.3 3.8 0.3 1.5 4.4 11.0 0.3 66.2 94.7 31.0 0.2 1.1 4.9 220.9 132.8 0.4 8.5 0.2 0.2 0.2 200.6 0.5 27.7 2.2 7.3 0.7 0.5 2.2 27.7 1.6 139.2 1.7 16.8 5.0 132.4 0.6 13.5 0.4 5.0 0.6 0.6 266.4 0.6 0.2 4.4 0.6 0.3 0.0 0.7 0.2 0.0 0.1 3.4 17.7 58.4 17.6 1.2 0.2 13.8 25.8 0.0 0.1 0.1 0.3 14.3 0.3 24.6 0.0 0.0 0.4 0.4 0.0 0.0 0.1 0.0 5.4 0.1 0.2 16.1 3.0 0.1 0.3 0.3 1.7 6.4 123.7 8.8 1.6 28.9 0.3 55.2 0.6 31.4 4.6 0.2 5.4 0.8 1.1 0.9 5.4 1.0 1.1 19.2 0.7 19.6 6.3 0.8 0.6 29.2 0.9 17.9 0.2 0.0 0.8 0.0 0.0 0.6 6.9 0.0 0.0 0.0 10.7 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.3 58.6 153.7 166.2 94.5 66.2 94.7 220.9 132.8 200.6 139.2 132.4 266.4 0.1 6.4 1.5 1.0 22.0 0.0 1.8 0.3 6.8 0.0 5.7 6.1 0.8 8.6 3.9 25.8 0.0 0.0 0.1 19.0 9.8 1.4 9.2 9.6 1.7 0.5 48.4 0.0 1.0 13.1 0.0 0.6 19.4 21.4 0.0 0.2 0.0 0.0 0.0 0.0 3.7 27.9 0.0 0.0 0.0 3.5 1.2 0.5 1.8 2.8 0.0 0.0 0.0 98.5 821.1 10.8 14.6 0.0 4.0 0.7 24.2 1.4 1.5 0.0 0.0 0.0 0.4 20.9 34.0 5.9 0.1 0.0 0.4 0.1 26.9 0.9 ULBP3 RAET1N ENSG00000131019 "UL16 binding protein 3" Q9BZM4 6 150061053-150069121 "Predicted intracellular proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 6.5;testis: 6.3" "Cell type enhanced" "Detected in single" "Gastric mucus-secreting cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA056541, HPA063007" Approved Uncertain "Vesicles,Centriolar satellite" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" Vesicles "Centriolar satellite" "HPA056541: , HPA063007: AB_2684920" "unprognostic (4.87e-2)" "unprognostic (4.49e-2)" "unprognostic (3.14e-3)" "unprognostic (1.50e-2)" "unprognostic (1.86e-2)" "unprognostic (2.99e-2)" "unprognostic (8.47e-2)" "unprognostic (1.96e-1)" "unprognostic (5.87e-2)" "unprognostic (8.71e-2)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (6.26e-2)" "unprognostic (3.43e-1)" "unprognostic (2.12e-1)" "unprognostic (5.45e-2)" "unprognostic (5.16e-2)" 1.3 1.2 1.6 0.7 1.8 0.7 1.0 1.6 2.4 0.5 0.4 0.8 1.1 1.0 0.9 1.5 2.0 1.3 0.7 1.7 1.4 1.7 1.0 1.5 0.5 0.9 0.9 0.8 0.7 0.9 0.1 0.9 0.9 0.7 0.8 0.8 0.4 0.5 6.5 1.1 0.5 0.5 0.2 0.6 1.9 6.3 1.3 0.5 4.9 0.4 0.9 1.0 0.5 1.9 6.2 2.0 6.5 7.3 1.6 11.9 2.3 6.1 2.6 7.2 8.0 11.0 5.1 0.2 11.8 9.9 10.9 8.3 17.7 20.5 7.7 3.7 7.8 0.6 2.9 0.5 2.5 0.1 1.1 10.2 3.5 15.0 8.1 6.9 9.7 0.2 0.5 0.8 6.3 7.0 0.3 0.5 3.1 2.6 14.8 6.2 5.9 0.3 17.5 12.4 1.2 0.5 12.2 8.2 3.0 3.4 2.5 1.7 5.6 1.2 9.8 20.5 13.3 0.3 0.2 4.1 9.6 3.7 5.1 0.8 0.2 0.2 2.2 0.2 2.9 0.8 1.5 2.4 0.2 0.5 0.8 1.2 1.0 0.6 0.2 0.3 2.3 0.4 1.6 1.8 1.6 2.4 1.7 1.4 0.9 0.9 0.9 0.2 1.3 1.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 UMOD ENSG00000169344 Uromodulin P07911 16 20333051-20356301 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 693 "kidney: 2277.8" "Group enriched" "Detected in some" 146 "Collecting duct cells: 248.3;Distal tubular cells: 950.9" "Cancer enriched" "Detected in single" 39 "renal cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009446, HPA043420, HPA054721" Enhanced "Secreted in other tissues" NA NA 55000000 66000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: Non-specific - Basic cellular processes" "CAB009446: AB_2212378, HPA043420: AB_2678474, HPA054721: AB_2682585" "unprognostic (2.51e-2)" "unprognostic (1.33e-1)" "unprognostic (6.45e-2)" "unprognostic (3.02e-2)" "unprognostic (1.49e-2)" "unprognostic (1.43e-1)" 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2277.8 0.8 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 248.3 0.0 0.0 0.0 0.0 950.9 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UNC119 "HRG4, POC7, POC7A" ENSG00000109103 "Unc-119 lipid binding chaperone" Q13432 17 28546708-28552631 "Disease related genes, Predicted intracellular proteins" "Endocytosis, Protein transport, Sensory transduction, Transport, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 20 "retina: 1168.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 671.1;Cone photoreceptor cells: 856.9;Muller glia cells: 301.5;Rod photoreceptor cells: 2038.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041912 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA041912: AB_10795267" "unprognostic (8.93e-2)" "unprognostic (3.34e-1)" "unprognostic (1.98e-1)" "unprognostic (1.14e-3)" "unprognostic (4.95e-3)" "unprognostic (2.10e-1)" "unprognostic (1.44e-2)" "unprognostic (6.64e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (2.76e-3)" "prognostic favorable (8.09e-5)" "unprognostic (2.65e-1)" "unprognostic (8.08e-3)" "unprognostic (5.51e-3)" "unprognostic (1.87e-1)" "prognostic unfavorable (9.82e-4)" "unprognostic (1.71e-3)" 17.7 29.3 48.1 23.6 47.8 55.9 20.7 44.0 59.2 25.9 54.7 19.9 12.0 21.3 17.8 25.3 19.1 14.3 24.5 49.7 49.5 36.6 32.9 21.1 29.7 49.3 45.9 21.3 24.5 22.2 28.8 11.0 49.7 29.8 10.9 1168.7 26.7 20.1 6.1 32.6 26.0 13.7 43.9 55.5 20.3 53.1 51.4 17.5 23.1 6.2 29.6 22.9 25.9 45.6 24.9 30.7 30.0 42.0 31.1 30.2 14.7 20.0 27.4 35.7 33.4 42.7 8.1 20.2 21.2 30.9 24.5 39.7 25.6 29.8 19.0 37.6 47.8 14.0 15.5 13.2 21.3 20.9 42.1 27.8 40.4 25.7 12.7 33.4 28.9 21.5 14.6 16.3 22.1 39.1 20.8 20.8 29.3 21.0 21.9 32.8 49.2 9.0 27.2 27.2 11.7 41.1 28.8 46.4 31.1 34.5 36.7 35.7 22.1 20.4 38.5 33.3 19.8 18.6 20.7 4.6 33.7 33.5 19.1 21.6 48.7 120.2 8.9 122.1 8.9 29.1 16.9 13.7 82.3 42.6 18.7 13.4 131.5 18.2 212.4 93.4 16.5 36.3 48.1 47.8 44.0 59.2 49.7 49.5 49.3 45.9 49.7 43.9 51.4 45.6 10.4 0.0 5.4 5.2 34.5 13.4 16.3 38.8 34.1 671.1 25.2 33.8 12.6 18.6 17.9 12.9 856.9 25.3 48.7 22.9 33.2 20.4 3.0 5.5 8.4 24.0 25.3 4.8 8.8 18.3 9.0 13.6 11.2 7.8 12.7 14.1 8.9 13.8 34.6 146.4 11.3 14.3 34.6 41.0 89.8 6.6 14.6 44.6 19.6 4.7 56.8 301.5 59.8 4.5 1.2 17.8 16.4 21.4 19.6 22.1 23.8 20.6 6.7 2038.5 46.0 6.6 15.8 1.5 16.6 20.6 14.3 20.0 25.3 14.1 13.7 18.9 UNC45A "GC-UNC45, SMAP-1" ENSG00000140553 "Unc-45 myosin chaperone A" Q9H3U1 15 90930180-90954093 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Myogenesis" "Chaperone, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039228 Approved Supported "Nuclear speckles,Cytosol" NA NA 17000 "Cluster 27: Non-specific - Gene expression" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear speckles" Cytosol "HPA039228: AB_2676402" "unprognostic (1.46e-1)" "unprognostic (3.83e-2)" "unprognostic (4.51e-2)" "unprognostic (1.97e-1)" "unprognostic (2.68e-2)" "unprognostic (1.70e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (2.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (1.98e-1)" "unprognostic (9.85e-2)" "prognostic favorable (7.46e-7)" "unprognostic (9.30e-2)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-2)" 25.0 25.3 7.7 16.7 8.2 17.3 23.2 8.6 9.1 32.0 10.0 41.2 16.4 38.1 11.0 31.4 28.4 17.3 15.9 7.8 7.7 18.9 13.0 20.2 18.9 8.9 11.6 26.1 22.3 33.2 17.5 19.6 9.5 25.2 13.4 5.6 25.8 34.1 9.6 37.7 23.5 28.0 8.3 19.7 28.5 13.1 9.6 18.0 19.5 10.6 17.3 39.3 29.4 8.0 38.2 76.3 30.9 27.2 83.0 38.0 27.3 42.4 36.2 56.5 45.1 61.3 49.4 44.7 55.5 53.8 32.5 82.1 52.9 54.4 26.6 49.8 75.9 86.2 77.0 44.4 46.8 21.5 56.2 47.3 65.8 55.7 40.5 54.2 77.5 35.1 38.6 35.8 43.3 62.2 28.1 18.6 41.8 69.5 38.0 54.8 46.9 48.1 38.4 89.2 43.1 39.4 57.1 55.9 54.3 36.8 50.8 44.3 77.0 48.0 34.1 40.4 45.0 33.6 50.5 21.1 46.6 49.7 49.8 11.5 8.3 5.0 11.8 7.3 11.3 7.9 9.6 9.1 10.4 6.3 7.8 7.4 1.6 9.8 11.6 9.1 9.3 9.8 7.7 8.2 8.6 9.1 7.8 7.7 8.9 11.6 9.5 8.3 9.6 8.0 21.7 22.4 22.4 9.4 23.2 16.3 24.8 26.1 30.1 27.2 17.2 19.6 12.7 35.8 23.8 18.4 18.8 53.6 17.5 26.9 13.7 33.6 26.7 12.8 20.3 25.3 37.0 25.2 19.1 18.2 22.7 23.7 26.5 22.1 29.2 30.9 18.9 13.4 28.2 18.5 18.4 15.9 26.4 12.2 14.0 29.0 29.5 20.7 19.6 9.4 28.8 21.5 27.8 7.1 11.0 23.3 26.0 51.6 20.6 16.8 22.0 19.6 11.7 35.1 32.9 15.2 33.9 24.8 6.4 33.9 18.8 46.2 21.4 26.0 22.7 20.3 UNC5C ENSG00000182168 "Unc-5 netrin receptor C" O95185 4 95162504-95549206 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 2078.8" "Cancer enriched" "Detected in many" 4 "thyroid cancer: 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 82.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.55e-1)" "unprognostic (2.72e-1)" "unprognostic (1.35e-2)" "unprognostic (8.45e-2)" "unprognostic (3.03e-1)" "unprognostic (3.20e-1)" "unprognostic (3.48e-1)" "unprognostic (3.40e-1)" "unprognostic (3.12e-1)" "unprognostic (1.11e-3)" "unprognostic (1.68e-1)" "unprognostic (1.39e-1)" "unprognostic (2.70e-5)" "unprognostic (1.25e-2)" "unprognostic (1.16e-1)" "unprognostic (1.86e-1)" "unprognostic (3.62e-4)" 1.9 9.0 8.9 1.0 17.2 0.0 1.3 7.0 17.4 1.8 0.0 2.9 1.4 2.4 1.7 0.6 1.9 2.0 3.1 6.6 15.4 1.1 1.0 2.5 0.5 18.1 8.7 2.8 0.3 0.1 1.2 1.8 21.4 3.3 3.4 6.4 6.3 3.9 0.1 0.2 1.9 2.0 8.0 4.2 2.1 2.6 16.4 1.9 11.9 0.4 0.3 2.6 1.6 40.5 0.0 0.5 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.2 4.2 0.0 0.2 0.0 1.1 0.2 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 82.9 0.0 0.0 0.2 4.8 0.3 12.3 0.0 0.1 1.2 0.0 7.9 0.0 0.0 0.0 0.1 9.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 17.2 7.0 17.4 6.6 15.4 18.1 8.7 21.4 8.0 16.4 40.5 0.7 0.0 0.0 105.4 0.0 0.1 0.1 0.1 0.0 1.9 0.7 1.5 1.7 0.0 0.2 1.8 0.0 0.5 0.0 2.6 0.0 0.0 0.7 0.5 3.4 0.7 1.2 0.0 326.1 0.0 0.1 4.6 0.0 1.2 0.0 20.2 0.4 0.0 1.8 0.0 448.3 0.5 0.0 0.8 0.0 0.8 21.1 0.4 1.8 57.1 0.0 1.3 0.0 308.1 2078.8 0.0 26.9 11.7 0.0 0.3 0.0 0.1 0.0 12.5 6.6 0.3 4.6 0.0 0.1 0.0 0.0 0.0 0.1 0.1 1.1 0.0 UNC5CL "MGC34763, ZUD" ENSG00000124602 "Unc-5 family C-terminal like" Q8IV45 6 41026895-41039221 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 37.1;kidney: 58.6;liver: 52.8;pancreas: 36.2;stomach 1: 23.6" "Group enriched" "Detected in many" 6 "Cholangiocytes: 30.0;Collecting duct cells: 22.0;Ductal cells: 25.7;Exocrine glandular cells: 68.6;Gastric mucus-secreting cells: 36.7;Hepatocytes: 30.0;Pancreatic endocrine cells: 19.8;Proximal enterocytes: 37.3;Proximal tubular cells: 41.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "OE19: 44.8;RPTEC TERT1: 13.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA015725 Enhanced Approved Centrosome NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" Centrosome "HPA015725: AB_2669283" "unprognostic (1.10e-2)" "unprognostic (3.59e-2)" "unprognostic (1.60e-1)" "unprognostic (2.57e-1)" "unprognostic (7.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.16e-1)" "unprognostic (8.55e-3)" "unprognostic (3.58e-1)" "unprognostic (2.02e-2)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" "unprognostic (9.30e-2)" "unprognostic (2.35e-1)" "unprognostic (2.31e-1)" "unprognostic (1.19e-1)" "unprognostic (5.60e-6)" 1.2 1.0 1.3 1.0 1.6 0.9 1.6 1.3 1.7 1.5 1.2 3.1 37.1 1.1 0.3 1.3 1.9 9.2 1.2 1.3 1.3 58.6 52.8 2.1 1.0 1.7 1.4 1.5 36.2 0.3 0.8 0.4 1.6 1.5 1.3 0.8 1.7 0.6 0.7 1.9 29.4 0.4 1.4 3.3 23.6 2.2 1.5 2.7 1.6 0.2 0.7 1.1 1.1 2.3 0.5 0.2 0.6 0.9 0.2 0.1 0.6 0.0 0.1 0.0 0.0 7.0 0.1 0.1 2.5 0.0 0.0 0.2 0.1 0.2 0.1 1.1 1.3 0.6 0.0 3.8 0.1 0.3 0.2 0.1 0.6 0.0 0.4 0.1 0.0 2.8 0.5 0.4 0.0 0.1 0.9 2.3 0.2 44.8 0.2 0.9 0.1 0.5 13.0 0.0 0.6 0.6 0.0 0.0 1.3 0.7 0.1 0.2 0.2 0.0 0.4 0.3 0.1 4.3 2.3 0.6 0.0 1.5 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 1.3 1.6 1.3 1.7 1.3 1.3 1.7 1.4 1.6 1.4 1.5 2.3 0.3 3.2 1.1 4.2 1.3 0.8 0.6 0.4 0.6 0.6 1.0 1.0 0.8 30.0 0.3 22.0 4.2 0.4 1.8 2.3 3.9 25.7 2.4 0.6 0.3 0.4 1.2 0.4 0.3 68.6 0.8 0.5 36.7 1.6 0.0 0.3 1.4 30.0 0.3 1.7 0.2 5.0 0.0 0.8 0.3 0.4 0.3 0.8 1.8 0.0 0.8 0.2 2.1 0.0 3.5 19.8 3.1 0.7 0.3 0.6 37.3 41.8 0.9 0.3 0.0 0.3 0.4 0.9 0.8 0.5 0.1 0.8 1.0 0.1 5.4 0.4 UNK "KIAA1753, ZC3H5, ZC3HDC5" ENSG00000132478 "Unk zinc finger" Q9C0B0 17 75784806-75825799 "Predicted intracellular proteins" "Translation regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 130.3;Spermatocytes: 120.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023636, HPA027962" Uncertain Supported "Cytosol,Cytoplasmic bodies" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Cytosol, Cytoplasmic bodies" "HPA023636: AB_10601774, HPA027962: AB_10611522" "unprognostic (7.94e-2)" "unprognostic (4.79e-2)" "unprognostic (3.37e-1)" "unprognostic (1.04e-3)" "unprognostic (9.51e-2)" "prognostic favorable (2.02e-4)" "unprognostic (1.05e-2)" "unprognostic (1.11e-1)" "unprognostic (6.73e-2)" "unprognostic (9.78e-2)" "prognostic favorable (6.58e-5)" "unprognostic (5.31e-2)" "unprognostic (1.41e-3)" "unprognostic (6.69e-2)" "unprognostic (4.04e-1)" "unprognostic (1.99e-2)" "unprognostic (1.01e-2)" 12.0 11.7 8.5 8.6 9.1 8.4 13.6 9.5 9.6 20.9 9.6 12.7 6.8 18.2 4.0 13.7 17.5 5.3 10.5 7.4 7.8 15.1 12.8 10.1 10.6 9.4 8.8 22.1 14.8 9.8 20.1 5.8 8.1 16.0 3.4 5.6 14.2 6.4 9.1 18.4 14.1 4.7 7.4 21.2 11.4 9.3 10.0 10.1 16.9 4.2 5.2 14.0 15.3 13.0 9.3 14.7 16.0 13.6 5.0 4.6 13.0 6.1 6.6 6.7 8.2 5.4 10.5 19.8 5.2 6.6 11.1 8.4 8.1 7.3 3.1 10.3 26.6 12.4 12.8 11.6 6.7 9.6 15.2 9.1 4.4 5.8 6.2 7.6 8.9 14.0 6.5 9.6 5.4 18.6 21.4 13.2 6.9 6.5 9.6 22.4 16.0 10.1 6.3 9.8 14.7 28.8 7.9 11.0 22.0 8.0 13.4 14.7 6.5 15.9 8.6 7.1 7.9 16.4 5.1 11.0 11.5 6.1 10.0 0.0 0.2 0.1 0.5 0.1 0.4 0.2 0.2 0.3 0.1 0.7 0.4 0.4 0.0 0.2 0.2 0.4 0.3 0.4 8.5 9.1 9.5 9.6 7.4 7.8 9.4 8.8 8.1 7.4 10.0 13.0 12.7 16.0 17.0 33.6 25.4 15.2 17.3 19.3 10.2 26.4 16.5 14.7 11.2 11.5 21.3 3.7 14.6 9.1 18.9 11.4 3.9 15.3 130.3 14.7 11.8 13.3 16.8 10.9 15.4 22.9 15.8 14.1 15.8 9.1 19.0 15.6 7.9 6.0 14.3 21.9 21.1 13.3 38.7 10.8 14.3 22.6 19.0 10.1 26.6 28.1 10.8 22.5 18.6 27.2 26.0 21.3 12.7 10.5 24.4 12.9 7.0 6.1 24.0 24.4 19.7 15.1 15.5 120.5 73.5 13.0 21.9 17.2 19.1 10.5 14.0 13.9 UNKL "C16orf28, FLJ23360, ZC3H5L, ZC3HDC5L" ENSG00000059145 "Unk like zinc finger" Q9H9P5 16 1363205-1414751 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055801, HPA073949" Uncertain Supported Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 9: U-2 OS - Unknown function" "Cluster 52: Non-specific - Transcription" Cytosol "HPA055801: AB_2682926, HPA073949: AB_2686647" "unprognostic (5.32e-3)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (8.88e-2)" "unprognostic (4.08e-2)" "unprognostic (1.82e-2)" "unprognostic (3.90e-3)" "unprognostic (8.07e-2)" "unprognostic (5.18e-2)" "unprognostic (8.56e-2)" "unprognostic (4.85e-3)" "unprognostic (1.13e-1)" "unprognostic (3.86e-3)" "unprognostic (1.89e-1)" "unprognostic (6.27e-2)" "unprognostic (2.85e-1)" "unprognostic (1.55e-1)" 6.9 7.5 4.5 4.0 3.1 5.6 7.3 9.0 8.3 7.5 0.5 6.5 4.1 8.9 0.7 4.4 8.4 1.8 4.4 4.6 3.5 3.9 4.3 5.3 4.3 8.8 5.4 10.7 4.2 2.0 5.1 3.0 8.9 7.0 1.4 2.6 6.9 3.0 11.5 7.6 7.4 1.7 2.2 8.2 5.6 6.6 6.3 5.4 7.9 2.3 2.8 7.3 6.2 5.2 4.7 12.3 2.8 7.2 2.1 2.6 21.5 12.0 3.6 3.2 2.8 10.1 10.7 1.8 24.4 4.1 5.5 8.6 3.6 1.3 2.2 22.0 10.4 3.7 14.8 8.3 1.6 2.1 7.5 3.4 1.6 5.1 2.1 3.8 5.7 5.4 10.6 6.5 1.5 7.4 5.5 6.0 7.8 2.0 13.4 14.7 3.2 13.7 2.0 1.3 9.4 5.6 7.1 4.4 1.3 2.0 7.1 3.4 6.9 7.1 10.9 6.1 5.1 14.2 8.0 8.4 5.7 4.2 8.3 3.5 1.1 2.7 2.1 0.4 1.0 0.7 0.7 0.5 0.4 0.9 1.5 0.7 4.1 1.4 0.4 1.8 0.9 0.7 4.5 3.1 9.0 8.3 4.6 3.5 8.8 5.4 8.9 2.2 6.3 5.2 7.6 6.4 7.5 18.3 16.0 5.5 6.2 5.0 3.4 30.0 8.1 9.5 2.7 7.2 8.3 5.5 14.6 12.8 16.2 5.3 1.9 5.4 5.7 4.9 6.4 8.9 3.6 6.1 13.3 3.0 6.6 8.7 6.6 7.0 5.1 20.6 12.5 6.8 4.1 6.7 15.7 6.5 6.1 7.3 3.8 20.8 16.4 6.2 7.2 9.4 13.9 16.6 23.7 13.0 17.2 7.3 11.3 15.4 17.1 22.7 11.5 2.0 8.0 37.3 6.6 12.5 8.3 14.2 20.0 4.5 8.2 20.5 11.8 9.4 4.9 11.7 UPK3B "FLJ32198, MGC10902, p35, UPIIIb" ENSG00000243566 "Uroplakin 3B" Q9BT76 7 76510525-76516522 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 120.6;esophagus: 64.8;lung: 50.0;urinary bladder: 42.2" "Cell type enriched" "Detected in some" 5 "Alveolar cells type 1: 121.8" "Group enriched" "Detected in many" 12 "ovarian cancer: 64.6;urothelial cancer: 78.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 13.2;CAPAN-2: 48.2;HaCaT: 10.0;RT4: 34.7;T-47d: 27.1" "Not detected" "Not detected" HPA010506 Approved NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA010506: AB_1080479" "unprognostic (8.33e-2)" "unprognostic (1.30e-1)" "unprognostic (3.62e-3)" "unprognostic (2.26e-3)" "unprognostic (7.87e-2)" "unprognostic (8.60e-2)" "unprognostic (1.12e-1)" "unprognostic (2.63e-1)" "unprognostic (4.03e-1)" "unprognostic (5.92e-2)" "unprognostic (1.37e-2)" "unprognostic (4.06e-2)" "unprognostic (8.37e-9)" "unprognostic (3.56e-2)" "unprognostic (2.01e-1)" "unprognostic (1.66e-1)" "unprognostic (6.34e-2)" 120.6 0.7 0.1 0.1 0.4 0.1 1.4 0.0 0.4 8.0 1.0 1.2 0.0 0.7 0.2 64.8 10.0 0.1 10.6 0.0 0.2 0.6 1.0 50.0 0.1 0.1 0.2 6.9 1.3 0.0 1.7 0.0 0.2 2.7 0.0 0.2 8.3 0.0 0.5 4.1 0.9 0.0 0.0 2.1 2.9 4.2 0.7 0.0 1.4 0.0 1.8 42.2 12.1 0.1 1.1 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 48.2 0.0 0.4 0.0 0.1 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 2.9 0.1 0.0 0.0 0.0 0.0 34.7 0.0 0.0 0.3 3.9 0.0 0.1 27.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.0 0.2 0.1 0.2 0.2 0.0 0.7 0.1 0.3 121.8 3.3 0.0 0.3 1.7 0.4 18.3 4.6 0.4 0.2 0.0 0.3 20.0 20.4 3.7 4.2 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.0 0.9 0.0 0.0 0.0 0.0 0.0 13.9 1.1 0.5 1.3 0.1 0.7 0.1 0.1 1.7 0.0 0.0 6.1 0.3 2.5 0.0 12.2 0.3 3.6 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.1 0.0 11.1 0.2 0.0 0.0 1.1 0.0 0.1 2.1 2.8 0.1 0.4 0.0 0.2 14.2 USP11 UHX1 ENSG00000102226 "Ubiquitin specific peptidase 11" P51784 X 47232866-47248328 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 203.6;Horizontal cells: 139.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003103, HPA037536" Enhanced Supported Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm Cytosol "HPA003103: AB_10671088, HPA037536: AB_10672904" "unprognostic (1.60e-1)" "unprognostic (2.77e-3)" "unprognostic (5.84e-2)" "prognostic unfavorable (2.95e-4)" "unprognostic (3.08e-2)" "unprognostic (2.02e-1)" "unprognostic (6.11e-3)" "unprognostic (9.21e-2)" "unprognostic (3.18e-2)" "unprognostic (3.52e-1)" "unprognostic (3.29e-3)" "unprognostic (3.74e-2)" "prognostic favorable (4.13e-5)" "unprognostic (3.14e-2)" "unprognostic (9.23e-2)" "unprognostic (9.51e-2)" "unprognostic (7.11e-2)" 25.5 32.8 117.7 23.7 118.7 11.2 26.8 41.5 116.3 51.2 30.0 33.9 11.5 47.0 23.6 18.2 49.9 24.5 45.5 113.1 148.1 33.3 12.7 30.9 30.1 69.8 78.3 76.4 27.1 36.6 103.7 24.9 93.9 33.4 14.1 84.8 21.4 38.7 32.4 18.5 25.5 35.9 65.4 29.3 24.9 46.2 122.8 42.6 52.2 29.6 28.9 36.9 31.7 79.8 45.6 70.7 117.6 81.0 43.4 28.5 33.0 34.0 52.5 65.6 73.3 67.4 36.7 29.9 26.1 60.5 70.5 53.5 94.7 24.0 56.4 47.1 73.5 34.7 52.9 61.4 50.7 39.2 70.7 42.1 9.8 69.1 29.3 37.3 26.7 68.9 26.6 3.9 51.8 70.0 77.8 43.4 89.2 24.3 62.5 86.1 114.3 25.1 32.4 60.9 66.8 114.4 62.6 12.4 37.7 73.9 26.0 23.0 28.2 56.0 58.0 79.3 39.6 54.3 36.2 51.3 34.3 48.8 50.8 63.9 9.1 19.9 55.4 19.6 48.3 53.1 24.5 54.3 11.9 53.1 36.6 76.3 5.5 56.4 24.3 53.2 35.0 46.0 117.7 118.7 41.5 116.3 113.1 148.1 69.8 78.3 93.9 65.4 122.8 79.8 13.6 22.4 17.7 25.8 53.5 13.6 42.2 30.9 21.6 203.6 13.0 23.5 24.2 7.2 31.5 33.1 56.3 20.9 52.2 9.4 50.9 18.3 26.4 28.2 26.3 22.5 35.4 18.3 43.3 10.2 15.0 41.3 22.4 28.3 45.7 56.6 22.1 8.2 13.4 139.7 63.7 8.7 28.5 12.0 16.3 41.0 29.5 17.9 28.4 19.7 17.5 96.2 23.7 25.1 24.8 12.5 7.9 42.2 48.1 18.6 4.7 15.2 46.4 63.4 26.3 57.2 40.2 18.3 87.8 11.9 6.5 16.3 44.6 34.2 8.9 26.0 USP14 TGT ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported "Plasma membrane,Cytosol" NA NA 2700000 "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA001308: AB_1080499" "unprognostic (2.21e-1)" "unprognostic (4.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-3)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.81e-5)" "prognostic unfavorable (4.30e-5)" "unprognostic (5.14e-2)" "unprognostic (5.00e-2)" "prognostic favorable (7.91e-4)" "unprognostic (1.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (3.76e-2)" 26.0 21.5 19.9 22.7 21.3 23.9 17.0 20.1 22.9 15.5 13.9 17.8 13.9 17.0 23.8 24.0 14.6 14.6 24.8 21.0 24.5 23.4 25.3 15.1 21.6 25.4 21.7 13.3 13.0 21.2 14.3 26.5 25.7 29.7 19.3 15.5 15.2 19.6 55.6 15.4 12.4 24.7 20.3 13.8 15.1 17.9 26.0 21.8 20.4 36.4 31.3 22.6 15.3 23.3 91.6 75.4 62.7 64.5 60.7 60.0 109.6 115.5 64.9 118.9 110.5 98.9 48.7 133.1 86.6 99.1 114.4 50.9 125.1 91.7 134.9 38.7 59.0 72.5 46.0 78.1 60.5 184.1 70.8 48.4 69.1 122.3 69.5 55.0 93.5 65.9 106.2 99.3 119.1 76.2 105.2 52.4 59.4 56.0 83.5 87.8 78.6 98.0 88.7 79.9 71.8 60.1 120.7 59.2 52.5 68.0 58.2 51.5 103.9 138.7 104.3 128.8 170.6 62.3 125.7 130.9 80.0 77.3 88.4 10.7 18.1 13.8 27.9 25.8 33.6 21.1 27.5 29.5 25.6 16.4 26.7 26.2 1.5 39.3 20.5 18.7 28.6 19.4 19.9 21.3 20.1 22.9 21.0 24.5 25.4 21.7 25.7 20.3 26.0 23.3 40.0 22.4 40.4 27.7 52.7 58.6 53.3 42.0 51.8 58.0 33.4 23.5 44.9 31.5 48.3 44.1 31.3 92.3 58.1 22.5 45.0 60.6 70.9 44.9 56.3 43.1 22.1 102.0 58.8 54.0 71.8 49.0 43.8 80.8 34.8 47.1 28.2 45.4 50.9 116.1 54.4 22.5 46.8 31.5 53.4 21.6 31.7 45.5 35.6 33.7 48.8 39.4 46.4 35.2 74.8 75.8 16.9 45.9 72.7 71.4 15.2 56.0 40.2 50.3 0.0 49.6 51.4 34.1 68.1 57.9 52.4 135.6 55.0 58.9 33.5 51.8 USP3 ENSG00000140455 "Ubiquitin specific peptidase 3" Q9Y6I4 15 63504511-63594640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 36.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053275, HPA060513, HPA077975" Supported "Nucleoplasm,Midbody ring" "Intracellular and membrane" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 50: Non-specific - Ribosome" "Cluster 15: RT4 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Midbody ring" "HPA053275: AB_2682096, HPA060513: AB_2684299, HPA077975: AB_2732365" "unprognostic (4.63e-3)" "unprognostic (2.71e-1)" "unprognostic (7.88e-2)" "unprognostic (3.33e-2)" "unprognostic (2.16e-2)" "unprognostic (6.03e-2)" "unprognostic (6.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.62e-2)" "unprognostic (2.36e-1)" "unprognostic (3.54e-2)" "unprognostic (4.87e-2)" "unprognostic (1.17e-1)" "unprognostic (8.61e-2)" "unprognostic (2.78e-1)" "unprognostic (6.21e-2)" "prognostic favorable (1.38e-4)" 12.7 8.2 5.8 5.4 7.0 21.4 11.2 36.4 5.9 11.7 15.4 13.4 6.5 12.9 4.7 10.9 10.9 5.4 6.0 5.3 6.3 10.1 8.2 13.2 6.5 6.9 6.9 16.2 18.9 3.1 6.2 2.7 7.6 10.4 5.6 6.3 12.4 6.0 10.0 14.6 13.9 4.5 5.3 17.6 15.7 5.3 8.6 7.4 9.1 3.6 6.4 12.4 11.9 7.5 10.4 21.0 12.1 8.1 5.5 7.6 8.2 6.7 9.6 7.1 5.8 6.6 13.1 8.7 15.3 9.3 3.6 12.0 11.6 11.1 5.6 12.2 5.8 10.4 8.6 9.8 6.8 6.4 11.4 11.3 7.8 7.7 10.6 8.9 12.4 17.3 9.5 9.0 3.3 5.2 11.0 8.8 16.2 13.7 5.3 22.2 8.4 11.3 4.5 23.8 9.6 9.5 3.3 13.0 6.7 7.8 5.5 9.5 13.4 7.2 16.9 3.3 10.3 9.3 24.4 18.2 7.4 13.8 7.5 120.0 84.7 12.7 24.8 66.0 28.4 34.1 34.3 26.0 59.8 34.8 34.0 25.2 169.1 19.8 65.4 13.1 28.1 45.2 5.8 7.0 36.4 5.9 5.3 6.3 6.9 6.9 7.6 5.3 8.6 7.5 23.6 38.5 69.2 76.7 63.4 52.6 34.3 24.8 23.3 31.4 27.9 20.3 9.2 25.8 41.4 16.5 12.5 19.8 48.4 37.6 41.1 41.0 21.6 37.8 32.8 26.0 43.8 15.8 11.2 37.2 57.3 28.3 39.8 74.6 27.1 64.5 11.4 24.0 24.8 13.5 40.0 35.4 30.5 78.4 109.6 77.4 15.8 74.5 42.7 75.9 101.8 25.9 41.2 80.4 40.6 39.8 35.6 18.4 69.7 40.6 33.2 28.3 33.3 17.9 13.1 25.3 34.5 14.8 40.3 33.9 59.0 34.1 64.6 40.1 40.6 37.6 USP30 "FLJ40511, MGC10702" ENSG00000135093 "Ubiquitin specific peptidase 30" Q70CQ3 12 109023089-109088023 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 52.7;Oligodendrocytes: 41.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016952 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA016952: AB_1858680" "unprognostic (2.34e-1)" "unprognostic (1.57e-2)" "unprognostic (7.04e-2)" "unprognostic (9.91e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (1.91e-1)" "unprognostic (3.60e-3)" "unprognostic (1.98e-1)" "unprognostic (4.96e-2)" "unprognostic (5.07e-2)" "unprognostic (1.07e-1)" "prognostic favorable (5.23e-6)" "unprognostic (2.49e-1)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-3)" 8.4 8.8 2.9 7.3 6.0 10.7 6.5 4.2 5.4 6.6 1.9 10.2 11.4 7.8 4.7 5.6 8.0 5.9 6.8 3.3 6.9 9.1 16.3 6.8 8.8 5.2 4.3 12.4 8.6 14.4 4.2 5.1 5.5 6.8 8.4 10.7 7.7 6.7 10.0 6.6 11.1 6.2 3.0 7.9 6.5 13.8 5.0 6.3 8.2 8.7 4.5 4.3 3.3 14.1 5.3 4.1 10.7 9.2 7.3 8.3 5.9 5.9 7.8 6.8 5.9 4.9 3.9 13.6 4.8 5.9 6.1 5.6 9.4 6.3 7.7 16.0 11.7 4.2 3.8 7.1 7.8 8.7 4.6 10.1 7.4 5.9 6.0 17.5 8.0 13.8 6.8 6.1 5.9 6.3 13.8 5.0 3.2 6.3 11.3 14.7 7.6 8.1 5.4 6.4 9.7 8.6 8.0 5.6 6.3 7.8 14.5 6.8 5.5 5.9 3.3 5.9 3.7 16.0 14.4 19.3 6.5 5.0 6.9 14.0 8.4 16.2 17.5 14.0 20.2 17.3 14.7 16.8 5.6 17.0 15.2 14.1 5.1 23.3 11.7 15.2 14.4 7.4 2.9 6.0 4.2 5.4 3.3 6.9 5.2 4.3 5.5 3.0 5.0 14.1 3.9 0.0 4.6 10.7 2.5 2.0 2.2 4.1 6.2 9.1 4.8 4.1 8.6 10.0 5.6 5.5 8.4 5.7 3.4 14.3 0.0 4.7 27.3 3.6 3.8 3.6 6.7 5.7 18.8 5.7 4.2 4.4 1.5 3.2 0.0 11.8 4.2 18.3 5.7 6.7 22.7 8.4 0.0 3.5 1.4 52.7 3.7 2.2 1.8 7.5 3.5 6.9 4.1 16.6 41.8 5.3 5.6 3.8 6.7 1.9 13.3 7.3 5.2 14.9 13.1 5.2 3.5 26.1 5.6 4.7 3.3 7.3 3.4 5.0 9.9 2.7 USP31 KIAA1203 ENSG00000103404 "Ubiquitin specific peptidase 31" Q70CQ4 16 23061406-23149270 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.2" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 198.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006937 Uncertain Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA006937: AB_1080523" "unprognostic (6.45e-2)" "unprognostic (2.42e-1)" "unprognostic (1.08e-1)" "unprognostic (4.43e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.52e-1)" "unprognostic (6.15e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (4.41e-5)" "unprognostic (5.59e-2)" "unprognostic (3.75e-1)" "unprognostic (3.07e-1)" "unprognostic (1.98e-3)" 5.5 2.9 7.5 2.0 23.4 4.3 6.7 18.9 13.0 12.9 0.7 4.2 1.7 11.0 3.8 6.0 5.3 1.9 9.2 10.0 10.5 3.6 5.6 6.1 1.8 22.3 20.3 2.2 4.3 5.5 5.7 3.9 21.3 7.5 2.3 3.2 4.6 4.1 8.9 11.2 2.6 7.5 11.3 1.6 2.6 11.8 20.6 2.6 3.0 8.4 2.5 7.5 7.9 31.2 12.0 12.4 3.5 4.9 6.2 4.8 3.3 4.1 3.7 5.1 6.1 7.9 7.1 4.0 4.2 5.1 8.3 15.2 8.7 15.9 8.4 2.9 3.5 1.6 7.4 16.7 7.8 4.2 4.3 4.1 13.5 9.5 21.8 1.9 9.3 3.9 4.9 12.0 7.1 8.0 2.0 3.5 6.9 3.9 3.8 9.9 9.8 7.9 7.7 17.5 9.3 6.0 6.3 12.4 3.6 3.9 5.0 9.2 5.5 10.3 7.6 5.3 11.2 3.9 7.0 4.2 7.4 5.5 4.2 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.0 7.5 23.4 18.9 13.0 10.0 10.5 22.3 20.3 21.3 11.3 20.6 31.2 25.9 6.4 3.7 11.1 2.2 66.8 62.7 35.5 44.9 13.7 7.6 19.8 13.6 7.2 10.9 5.5 2.1 13.8 3.6 2.7 0.0 7.0 4.8 20.6 12.8 17.6 4.8 8.2 59.2 8.6 7.5 6.9 2.0 13.2 1.3 23.7 7.5 27.7 4.7 0.0 49.6 3.5 12.2 3.5 10.8 10.4 7.8 5.0 7.2 32.8 3.1 4.0 3.1 31.7 198.7 7.9 2.0 4.5 2.8 32.0 1.5 11.6 17.6 8.1 19.7 8.8 11.2 24.2 57.1 17.4 26.6 7.5 2.9 4.4 6.4 23.9 USP32 "NY-REN-60, USP10" ENSG00000170832 "Ubiquitin specific peptidase 32" Q8NFA0 17 60177327-60422470 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 102.1" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 241.8;Inhibitory neurons: 113.1;Oligodendrocytes: 268.9;Rod photoreceptor cells: 136.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 59.2" "Group enriched" "Detected in all" 10 "dendritic cells: 59.2;granulocytes: 29.4" "Cell line enhanced" "Detected in all" "MCF7: 171.4" "Low region specificity" "Detected in all" HPA044365 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" Cytosol "HPA044365: AB_2678914" "unprognostic (4.10e-2)" "unprognostic (3.38e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.90e-3)" "unprognostic (2.33e-2)" "unprognostic (2.24e-1)" "unprognostic (3.93e-1)" "unprognostic (6.49e-2)" "unprognostic (2.78e-1)" "unprognostic (2.82e-1)" "unprognostic (1.97e-1)" "unprognostic (7.23e-2)" "unprognostic (8.35e-2)" "unprognostic (4.16e-2)" 16.1 21.8 13.6 15.0 27.8 32.1 14.1 23.2 23.6 12.4 25.2 13.0 9.5 10.3 6.8 21.7 10.7 11.8 17.4 14.3 22.8 20.2 26.6 20.7 10.5 22.2 25.0 10.0 12.5 19.2 11.9 13.2 24.8 10.8 11.4 58.8 12.9 11.2 40.8 21.0 10.5 13.7 18.1 18.5 12.2 102.1 22.3 14.4 20.6 29.2 11.6 13.1 14.7 44.4 32.6 38.2 19.0 30.8 44.8 45.3 17.2 26.4 41.9 34.5 45.8 18.6 20.0 19.4 21.5 50.0 56.1 16.3 33.1 36.9 61.5 16.8 13.9 39.7 31.8 19.5 44.1 31.7 33.6 39.6 24.6 49.9 45.2 33.5 38.6 24.4 42.9 17.1 41.1 171.4 32.3 21.3 21.7 29.6 18.8 15.8 51.6 11.5 33.1 24.5 13.1 19.1 22.9 6.0 33.8 32.1 27.4 41.3 32.6 49.7 54.9 33.1 23.5 16.2 37.4 19.6 24.6 23.6 33.4 14.5 4.3 16.5 2.0 3.7 1.4 3.0 1.4 1.7 8.5 2.2 1.0 1.9 29.4 1.3 4.6 59.2 2.6 2.1 13.6 27.8 23.2 23.6 14.3 22.8 22.2 25.0 24.8 18.1 22.3 44.4 8.0 6.4 16.4 58.8 12.5 26.9 13.3 5.8 11.4 17.3 9.2 7.6 8.2 10.0 10.1 5.5 241.8 5.1 12.6 8.5 3.9 11.3 95.0 9.0 9.9 9.8 8.3 44.2 92.3 7.5 8.4 12.6 15.8 11.6 11.4 18.5 12.5 12.0 18.5 13.5 113.1 5.6 6.1 29.7 41.3 33.3 13.1 25.1 5.4 101.2 28.0 10.4 24.7 70.4 268.9 9.6 11.4 5.7 8.3 10.3 7.4 4.6 7.0 136.4 26.3 11.9 9.1 92.7 14.9 11.2 21.9 4.9 10.9 8.5 5.5 8.2 USP43 FLJ30626 ENSG00000154914 "Ubiquitin specific peptidase 43" Q70EL4 17 9644698-9729687 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 37.9;Excitatory neurons: 35.5;Glandular and luminal cells: 52.5;Oligodendrocyte precursor cells: 73.4;Syncytiotrophoblasts: 73.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 11.7;SK-BR-3: 8.1;T-47d: 9.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA023389, HPA027762, HPA027763" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear speckles" "HPA023389: AB_1858691, HPA027762: AB_10603001, HPA027763: " "unprognostic (1.39e-1)" "unprognostic (1.75e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-3)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (2.04e-1)" "unprognostic (6.40e-3)" "unprognostic (2.26e-1)" "unprognostic (3.05e-3)" "unprognostic (2.41e-2)" "unprognostic (7.49e-2)" "unprognostic (5.95e-2)" "prognostic favorable (5.39e-4)" "unprognostic (3.24e-1)" "unprognostic (2.06e-1)" "unprognostic (3.28e-1)" 0.3 0.2 2.6 0.6 3.4 0.7 1.9 0.8 4.1 2.9 2.9 3.5 4.2 1.9 1.0 6.5 4.2 1.2 0.0 3.3 1.4 4.0 9.1 3.2 0.1 2.5 4.6 0.1 5.0 1.1 3.5 8.3 2.5 9.8 3.2 1.4 4.3 2.2 0.0 2.2 3.5 0.2 2.1 0.3 2.1 3.2 2.3 0.3 1.7 0.0 0.7 1.1 2.4 2.5 5.6 1.4 0.0 0.5 0.0 0.0 11.7 0.1 0.2 0.6 1.6 2.8 4.5 0.0 1.8 0.2 2.5 6.8 0.6 5.3 0.6 3.6 1.8 0.3 3.0 1.0 0.1 0.5 0.0 0.0 6.8 0.3 2.8 0.3 0.0 0.8 0.0 0.0 0.0 2.6 0.9 4.6 0.7 4.8 0.3 3.6 0.0 0.8 4.1 3.0 0.7 0.0 2.4 8.1 1.0 3.7 9.9 1.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 3.4 0.8 4.1 3.3 1.4 2.5 4.6 2.5 2.1 2.3 2.5 0.0 3.2 3.1 1.6 0.3 4.7 7.8 4.6 5.2 0.5 7.0 2.4 0.6 4.3 7.4 11.0 6.2 26.2 0.6 14.3 1.9 4.4 1.1 37.9 4.2 0.5 2.4 3.2 35.5 4.7 23.7 0.8 7.7 52.5 0.0 0.9 0.4 15.6 2.7 0.0 4.0 8.3 2.0 0.9 0.3 1.1 0.0 0.6 5.4 0.0 0.3 8.4 0.0 73.4 1.2 11.3 3.5 0.0 0.2 10.6 8.7 1.8 30.2 1.5 0.0 0.0 1.0 1.5 0.3 12.3 3.3 73.2 0.7 0.0 9.7 11.8 UTP4 "CIRH1A, CIRHIN, FLJ14728, KIAA1988, NAIC, TEX292" ENSG00000141076 "UTP4 small subunit processome component" Q969X6 16 69131291-69231130 "Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 100.0;Spermatogonia: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 398.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041139, HPA043542" Approved Supported "Nucleoli fibrillar center" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli fibrillar center" "HPA041139: AB_10961278, HPA043542: AB_2678542" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "unprognostic (1.89e-2)" "unprognostic (6.16e-3)" "prognostic unfavorable (9.05e-5)" "prognostic unfavorable (8.18e-7)" "unprognostic (1.31e-1)" "unprognostic (4.76e-2)" "prognostic favorable (2.88e-5)" "unprognostic (2.12e-2)" "unprognostic (4.45e-2)" "unprognostic (2.32e-3)" "unprognostic (9.57e-3)" "unprognostic (2.12e-1)" "unprognostic (1.33e-1)" "unprognostic (3.20e-2)" 25.4 17.4 7.7 17.5 8.6 27.1 21.0 7.3 10.1 16.3 7.3 21.1 10.8 20.6 9.9 23.0 19.5 12.7 19.2 10.3 7.5 31.7 19.1 16.3 19.1 6.1 6.9 18.3 24.1 16.6 14.2 15.5 6.6 16.1 17.6 11.4 15.7 14.4 61.7 20.2 13.9 22.7 5.9 14.0 19.1 31.4 8.0 17.6 23.2 26.3 23.3 28.8 16.8 7.3 79.6 95.6 56.9 79.8 48.5 42.9 94.5 83.7 57.2 152.1 112.8 188.1 68.8 166.4 68.0 57.7 63.1 106.0 130.8 102.7 167.4 33.2 74.6 82.2 58.6 99.7 58.6 96.5 52.7 41.0 55.2 143.0 129.5 40.7 68.6 88.8 169.4 22.9 90.0 96.2 105.4 50.5 139.1 80.3 66.7 174.3 85.3 163.4 63.6 77.7 96.4 67.1 178.3 45.3 48.3 63.3 80.2 53.4 48.2 83.3 83.6 73.4 119.2 59.5 116.1 398.1 56.5 76.5 87.4 4.5 18.6 3.5 26.7 26.1 38.5 30.6 30.0 26.9 25.6 20.1 34.7 31.6 1.7 35.0 19.4 21.6 31.5 30.2 7.7 8.6 7.3 10.1 10.3 7.5 6.1 6.9 6.6 5.9 8.0 7.3 12.1 6.4 11.4 0.0 14.6 0.0 30.0 0.0 28.5 5.7 12.4 11.6 0.0 5.7 9.9 5.5 8.4 18.9 7.4 1.7 9.8 27.4 17.9 7.0 13.2 12.1 0.0 12.4 0.0 25.4 22.1 14.8 10.2 9.0 2.5 12.0 9.3 7.9 16.7 6.7 0.0 6.4 0.0 8.9 0.0 7.6 15.8 9.8 0.0 0.0 8.2 7.6 11.3 0.0 0.0 24.4 5.4 14.7 13.4 26.7 4.5 100.0 5.8 5.7 6.6 26.7 12.8 30.1 49.5 25.1 0.0 12.9 11.0 16.5 10.0 22.6 UTS2 "PRO1068, U-II, UCN2, UII" ENSG00000049247 "Urotensin 2" O95399 1 7843083-7853512 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 43.0" "Cell type enhanced" "Detected in many" "dendritic cells: 15.3;granulocytes: 41.2;monocytes: 17.9;NK-cells: 88.6;T-cells: 18.2" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 5 "medulla oblongata: 43.0;pons: 27.0;white matter: 25.2" "Immune cell enriched" "Detected in many" 5 "T-reg: 45.2" "Lineage enriched" "Detected in many" 5 "T-cells: 45.2" "Cell line enhanced" "Detected in some" "CACO-2: 22.6;HEL: 7.1;HMC-1: 5.7;THP-1: 26.2" "Region enriched" "Detected in single" 19 "pons and medulla: 6.1" "Region enriched" "Detected in some" 12 "spinal cord: 79.7" HPA017000 Uncertain "Secreted to blood" NA NA 2590000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA017000: AB_1858656" "unprognostic (2.10e-3)" "unprognostic (1.35e-1)" "unprognostic (3.89e-3)" "unprognostic (1.33e-3)" "unprognostic (2.32e-5)" "unprognostic (1.09e-4)" "unprognostic (4.95e-2)" "unprognostic (6.69e-2)" "unprognostic (1.40e-1)" "unprognostic (2.65e-2)" "unprognostic (1.28e-1)" "unprognostic (1.89e-1)" "unprognostic (2.52e-5)" "unprognostic (1.75e-1)" "unprognostic (1.44e-1)" "unprognostic (2.47e-1)" "unprognostic (3.30e-3)" 0.5 3.7 0.1 0.5 0.1 2.9 0.1 1.5 0.5 0.3 0.0 0.7 0.6 0.1 0.0 0.1 0.4 0.5 0.0 0.2 4.6 0.3 0.1 0.5 1.8 43.0 6.2 0.3 0.0 0.0 0.0 0.0 27.0 1.4 1.2 0.9 0.0 0.0 0.3 0.3 0.5 1.2 4.0 1.1 0.2 0.0 0.9 0.9 0.1 0.0 0.3 0.2 0.1 25.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.1 0.0 0.2 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 8.5 0.1 0.6 5.0 0.0 6.7 0.0 4.4 4.5 0.8 0.0 0.4 1.3 0.1 6.1 0.0 0.0 45.2 1.7 0.1 0.1 1.5 0.5 0.2 4.6 43.0 6.2 27.0 4.0 0.9 25.2 0.1 0.0 1.9 0.0 5.1 1.5 0.1 0.1 1.8 3.2 0.0 0.0 0.1 0.0 0.7 1.8 0.0 0.0 15.3 2.7 0.0 0.0 0.0 0.0 0.1 0.3 1.2 1.7 0.4 0.0 0.0 0.6 1.1 0.1 41.2 0.0 0.0 0.0 0.1 5.0 0.5 3.7 0.0 0.0 1.3 0.0 0.0 5.5 0.0 1.0 17.9 0.8 88.6 0.5 0.2 0.1 4.7 0.0 4.3 1.2 3.0 0.6 0.0 1.2 0.0 0.2 0.3 0.0 0.0 0.8 0.4 0.1 18.2 0.0 8.0 0.0 UTS2B "U2B, URP, UTS2D" ENSG00000188958 "Urotensin 2B" Q765I0 3 191267168-191330536 "Predicted secreted proteins" Hormone "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 14.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;B-cells: 2.6;Early spermatids: 8.3;Late spermatids: 2.3;Oligodendrocyte precursor cells: 3.0;Spermatocytes: 2.6;Spermatogonia: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 4 "memory B-cell: 2.8;naive B-cell: 1.8" "Lineage enriched" "Detected in single" 5 "B-cells: 2.8" "Cell line enhanced" "Detected in some" "PC-3: 3.3" "Region enriched" "Detected in some" 9 "pons and medulla: 11.3" "Region enriched" "Detected in single" 46 "spinal cord: 6.0" HPA026992 Uncertain "Secreted - unknown location" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA026992: AB_1858703" "unprognostic (1.73e-2)" "unprognostic (4.38e-2)" "unprognostic (1.22e-1)" "unprognostic (3.41e-1)" "unprognostic (1.92e-1)" "unprognostic (2.17e-2)" "unprognostic (2.77e-2)" "unprognostic (2.14e-2)" "unprognostic (3.09e-1)" "unprognostic (2.63e-2)" "unprognostic (3.39e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (7.58e-2)" "unprognostic (2.08e-1)" "unprognostic (1.29e-1)" "unprognostic (3.10e-2)" 1.0 1.2 0.8 0.8 0.5 0.5 1.2 4.1 1.4 0.2 0.0 0.5 5.3 0.7 0.5 0.7 1.0 1.2 0.7 0.7 0.5 0.6 3.2 0.5 1.0 0.7 0.4 1.0 0.5 0.2 0.0 0.4 1.1 0.6 0.4 14.9 0.6 0.2 0.5 1.1 3.2 0.5 0.1 0.6 1.6 2.3 0.6 0.1 0.5 0.0 0.3 0.4 0.1 0.9 0.4 1.0 1.3 0.6 0.3 1.6 0.4 1.0 0.5 0.3 0.2 0.7 0.5 0.7 0.5 0.4 2.6 0.5 0.4 0.0 1.6 0.6 0.5 0.6 1.4 2.9 0.3 0.8 0.4 0.6 0.2 0.2 0.3 0.9 0.3 0.6 0.4 0.6 0.5 0.6 0.2 0.5 0.7 1.3 3.3 0.9 1.5 0.2 0.2 1.6 0.7 0.5 0.6 0.7 0.4 0.5 0.5 0.5 1.4 0.7 0.4 1.3 0.4 1.1 0.6 0.6 0.9 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.5 4.1 1.4 0.7 0.5 0.7 0.4 1.1 0.1 0.6 0.9 0.2 3.2 1.1 0.7 2.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 8.3 1.4 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 0.2 0.1 0.0 0.7 1.6 0.0 0.2 0.1 1.5 0.0 0.0 0.1 0.2 2.6 2.1 0.0 0.3 0.3 0.0 0.1 0.0 0.1 UTY "KDM6AL, KDM6C" ENSG00000183878 "Ubiquitously transcribed tetratricopeptide repeat containing, Y-linked" O14607 Y 13248379-13480673 "Enzymes, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Excitatory neurons: 66.7;Inhibitory neurons: 65.2;Oligodendrocytes: 65.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 20.6;SK-MEL-30: 14.9;U-266/84: 16.4;U-698: 20.2" "Low region specificity" "Detected in all" "HPA000568, HPA001165" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli rim" "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli, Nucleoli rim" "HPA000568: AB_1858705, HPA001165: AB_1080541" "unprognostic (7.52e-2)" "unprognostic (6.60e-2)" "unprognostic (4.04e-6)" "unprognostic (6.47e-2)" "unprognostic (9.34e-2)" "unprognostic (2.00e-2)" "unprognostic (9.17e-2)" "unprognostic (1.53e-2)" "unprognostic (1.29e-1)" "unprognostic (1.41e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.46e-2)" 3.6 3.5 0.9 2.4 1.5 6.8 3.5 2.0 2.2 0.0 1.6 2.9 2.5 0.0 9.4 4.1 0.0 3.5 2.9 0.9 1.2 3.1 4.1 4.2 2.1 2.1 1.1 0.0 3.4 2.9 4.0 3.4 2.1 8.1 6.2 4.5 4.3 6.2 5.7 5.1 6.3 0.0 1.3 3.4 2.9 3.8 1.4 0.0 3.8 5.2 6.0 3.6 0.0 3.2 0.0 2.5 0.0 0.0 0.0 0.0 8.7 4.5 7.7 5.0 7.5 0.0 0.0 12.4 0.0 5.1 0.0 0.0 0.0 0.0 6.9 6.9 0.0 20.6 0.0 0.0 6.4 0.0 0.0 7.8 7.8 0.0 0.0 0.0 0.0 4.2 0.0 0.0 5.5 0.0 7.1 0.1 0.0 0.0 0.0 0.0 3.1 5.6 5.4 8.3 4.9 0.0 0.0 0.0 14.9 8.5 0.0 4.4 5.9 8.7 0.0 0.0 3.1 13.5 16.4 20.2 0.8 0.0 0.0 1.8 1.7 3.8 2.6 1.9 3.7 2.9 2.6 2.1 1.8 3.2 3.6 2.7 3.9 5.8 2.2 2.9 3.2 1.1 0.9 1.5 2.0 2.2 0.9 1.2 2.1 1.1 2.1 1.3 1.4 3.2 0.0 16.0 25.3 58.4 35.4 11.3 18.4 8.2 44.3 35.2 0.0 0.0 6.1 5.7 10.7 18.4 64.6 10.0 8.0 3.0 0.0 4.8 0.4 0.0 0.0 9.0 1.8 19.6 66.7 0.0 3.7 9.3 37.8 0.0 16.4 0.0 12.5 2.1 3.0 37.0 65.2 3.3 2.0 14.2 14.5 2.0 10.8 12.7 8.8 54.4 18.1 12.8 25.7 57.8 65.8 1.5 2.2 11.7 23.2 14.0 2.9 2.6 10.7 37.4 0.0 4.7 5.0 4.0 6.8 33.2 15.3 13.3 25.1 0.0 2.9 21.3 UXS1 "FLJ23591, SDR6E1, UGD" ENSG00000115652 "UDP-glucuronate decarboxylase 1" Q8NBZ7 2 106093308-106194301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 323.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008825 Uncertain "Intracellular and membrane" NA NA 24000 "Cluster 20: T-cells - T-cell receptor" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA008825: AB_1858708" "unprognostic (4.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.63e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (5.45e-4)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.20e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.94e-4)" "unprognostic (3.95e-2)" "unprognostic (1.40e-2)" "unprognostic (8.46e-2)" "unprognostic (3.96e-2)" "unprognostic (6.18e-2)" "unprognostic (1.86e-2)" "unprognostic (5.32e-2)" 16.3 17.6 20.4 25.0 18.7 40.4 15.3 30.4 29.3 19.6 20.6 21.7 15.5 24.3 33.1 24.1 29.2 19.6 29.3 25.9 20.3 60.0 15.7 46.0 27.9 15.0 23.0 24.4 15.8 37.3 16.3 54.6 19.3 23.2 24.0 10.5 14.6 25.9 31.9 14.0 14.3 21.4 18.5 25.0 26.2 31.9 31.0 22.2 30.0 28.6 30.4 29.5 18.3 23.7 66.5 48.8 50.9 39.0 88.4 65.2 110.2 71.4 66.9 49.9 61.5 96.9 110.4 12.0 87.0 74.1 111.2 32.8 22.6 58.2 54.5 64.2 40.5 37.0 21.4 110.6 34.9 30.5 39.0 42.8 63.8 50.3 33.5 57.5 52.5 22.8 22.1 28.5 103.6 46.8 34.3 66.8 60.1 64.2 65.4 70.3 38.6 34.3 323.0 60.9 16.7 19.0 51.5 45.7 44.3 67.7 17.0 93.7 48.0 55.1 58.5 45.4 45.4 34.4 51.4 17.9 55.0 70.1 103.8 11.3 24.7 28.5 23.1 20.8 25.7 15.3 64.3 41.4 19.1 30.5 68.8 49.1 6.1 37.5 16.0 13.5 130.4 44.3 20.4 18.7 30.4 29.3 25.9 20.3 15.0 23.0 19.3 18.5 31.0 23.7 15.4 89.8 88.8 18.9 22.1 16.8 26.8 117.3 14.8 9.9 11.6 10.5 18.7 17.2 61.6 86.5 4.2 71.2 17.7 20.5 50.9 46.9 80.2 41.5 19.3 25.5 6.6 12.0 49.8 25.0 74.1 34.2 16.8 40.6 29.8 13.1 10.8 15.0 33.2 8.4 37.5 15.6 34.6 20.1 12.5 18.5 15.2 33.9 14.2 33.7 56.2 10.8 18.6 24.1 11.7 30.4 16.2 12.8 10.2 35.7 9.6 17.5 38.8 7.9 19.7 19.0 35.1 17.0 81.6 22.6 13.2 24.6 33.7 51.6 18.0 19.8 VASH1 KIAA1036 ENSG00000071246 "Vasohibin 1" Q7L8A9 14 76761468-76783015 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 67.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 139.7;Early spermatids: 72.8;Late spermatids: 95.3;Microglial cells: 53.4;Rod photoreceptor cells: 98.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 46.1;HEL: 35.1;HUVEC TERT2: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000653 Uncertain "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA000653: AB_1080551" "unprognostic (1.47e-1)" "unprognostic (9.13e-2)" "unprognostic (2.56e-2)" "unprognostic (7.29e-2)" "unprognostic (1.93e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-3)" "unprognostic (1.62e-1)" "unprognostic (9.23e-2)" "unprognostic (6.94e-2)" "prognostic favorable (6.56e-6)" "unprognostic (8.84e-2)" "unprognostic (6.44e-3)" "unprognostic (2.69e-1)" "unprognostic (1.92e-1)" "unprognostic (5.06e-2)" "unprognostic (1.73e-1)" 12.1 18.5 33.2 12.3 34.0 3.0 7.4 30.8 28.8 9.2 21.3 7.9 5.6 11.9 4.2 4.3 8.7 9.0 36.0 28.1 30.8 8.1 3.8 16.0 7.8 38.7 36.3 13.4 5.7 3.9 13.7 19.9 36.6 6.5 5.2 67.6 5.6 4.5 7.5 4.6 8.2 11.5 37.1 18.3 5.1 13.2 36.1 3.2 6.1 7.0 6.6 8.5 6.6 36.4 1.1 5.6 46.1 13.8 11.6 8.4 2.3 4.0 1.3 3.4 1.4 1.5 3.1 2.1 2.8 3.2 4.2 1.3 7.3 1.5 1.0 25.0 5.3 35.1 3.4 1.5 6.9 1.5 3.5 4.5 0.3 1.3 0.2 10.4 85.0 6.2 1.6 0.4 1.1 7.1 1.3 3.0 4.7 1.4 2.8 1.3 4.6 1.0 0.9 2.6 19.1 14.8 4.6 1.8 2.2 9.1 7.8 7.4 24.2 4.3 9.6 5.2 2.0 2.0 1.1 1.2 6.1 11.2 8.3 0.0 0.8 0.0 0.6 2.0 0.5 0.1 0.3 0.3 1.3 0.3 0.2 0.3 0.0 0.2 2.7 2.4 0.1 0.5 33.2 34.0 30.8 28.8 28.1 30.8 38.7 36.3 36.6 37.1 36.1 36.4 17.3 0.0 2.3 7.2 2.7 0.6 0.0 0.3 0.0 9.4 0.9 2.4 10.9 1.5 0.7 1.8 139.7 0.4 11.1 0.0 0.0 0.9 72.8 0.8 7.7 27.5 6.7 0.0 13.4 0.0 0.3 7.6 1.5 0.6 12.0 18.1 31.8 1.2 14.8 0.0 11.9 0.4 2.0 14.2 9.3 95.3 1.8 23.6 1.8 53.4 7.6 15.2 3.1 21.6 21.8 0.3 0.0 3.0 0.4 0.0 0.0 0.2 0.0 98.8 13.1 5.5 10.0 0.8 2.3 0.4 0.1 0.3 1.8 5.7 0.2 0.1 VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 975.7;Granulosa cells: 1131.8;Kupffer cells: 547.3;Macrophages: 605.6;monocytes: 948.1;Oligodendrocyte precursor cells: 1644.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 20 "dendritic cells: 88.9;monocytes: 240.0" "Cell line enhanced" "Detected in many" "AF22: 300.5;HSkMC: 199.5;hTERT-RPE1: 959.0;RPTEC TERT1: 381.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" 42.0 23.9 18.6 74.9 20.8 32.6 15.6 24.2 23.0 29.4 5.2 11.3 3.8 17.8 1.8 3.8 8.6 30.5 45.0 25.7 27.8 6.5 2.7 34.4 2.3 36.1 19.3 2.1 3.1 2.4 2.1 73.5 31.3 6.8 10.7 0.2 7.6 4.2 3.9 11.2 5.7 48.0 28.9 13.9 7.7 4.8 44.9 2.7 6.6 6.8 1.9 48.3 7.2 42.7 0.2 5.6 300.5 0.1 119.8 81.5 0.1 2.3 6.2 2.1 1.5 3.1 0.2 0.0 45.2 111.5 3.9 0.0 0.4 0.4 1.7 0.1 9.8 2.1 0.0 2.3 5.5 0.1 0.0 199.5 0.1 127.6 1.2 959.0 0.1 0.0 0.0 0.1 64.6 0.0 0.5 0.0 51.1 0.0 10.3 0.0 63.0 0.1 381.0 0.0 3.6 15.5 0.0 0.0 0.2 33.2 0.2 0.5 116.5 90.6 0.5 168.3 179.0 0.0 0.1 0.2 41.8 0.1 16.4 8.3 240.0 0.5 0.5 31.3 0.3 0.2 0.1 0.1 88.9 0.1 0.1 0.0 3.9 0.5 3.5 1.7 0.0 94.0 18.6 20.8 24.2 23.0 25.7 27.8 36.1 19.3 31.3 28.9 44.9 42.7 23.4 19.2 19.8 128.9 5.5 38.6 10.6 14.9 1.2 0.0 1.8 1.9 8.2 44.3 17.5 25.8 0.0 5.9 7.4 0.0 0.0 1.9 3.0 64.4 975.7 29.9 0.0 5.2 1.5 0.7 7.0 348.1 3.6 241.3 12.6 1131.8 16.8 3.6 25.6 0.0 30.7 0.2 0.0 547.3 83.1 2.5 18.6 605.6 44.4 20.6 948.1 0.0 13.4 1644.7 1.5 32.3 1.1 117.8 2.5 2.5 0.0 1.8 16.2 0.0 0.0 11.0 80.6 0.9 1.2 1.1 28.7 11.5 12.7 1.6 0.3 0.9 VEGFA "VEGF, VEGF-A, VPF" ENSG00000112715 "Vascular endothelial growth factor A" P15692 6 43770184-43786487 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 349.4;Muller glia cells: 265.8" "Cancer enhanced" "Detected in all" "renal cancer: 79.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 398.9;U-87 MG: 628.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005429, CAB039240, HPA069116, CAB069907" Supported "Secreted to blood" NA NA 562000 57000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "CAB005429: AB_2212984, CAB039240: , CAB069907: AB_10001947, HPA069116: AB_2686089" "unprognostic (1.12e-1)" "prognostic unfavorable (4.50e-4)" "unprognostic (2.42e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (4.35e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (2.34e-5)" "unprognostic (5.10e-2)" "unprognostic (5.27e-3)" "unprognostic (2.30e-2)" "unprognostic (1.40e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (1.76e-5)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.73e-4)" 155.8 52.7 17.6 36.5 20.3 45.5 92.4 34.2 28.2 45.2 46.8 32.6 50.9 104.0 10.5 61.3 40.9 80.1 208.3 22.8 25.1 116.9 217.3 94.1 9.3 27.0 38.5 25.0 68.1 105.0 22.3 46.2 26.8 120.3 21.4 229.1 32.1 17.8 221.2 44.2 44.6 57.1 19.6 70.1 63.9 5.3 32.0 5.6 270.9 150.9 9.5 122.3 61.7 24.9 76.5 13.4 12.5 71.8 21.0 32.9 84.2 45.6 81.1 29.7 58.4 43.1 9.9 24.9 35.5 27.7 305.4 30.6 34.0 92.0 52.0 27.4 10.4 19.0 17.8 29.2 220.3 20.8 40.4 58.0 178.6 290.6 286.2 398.9 7.7 21.0 35.7 121.7 109.4 31.3 2.3 28.3 7.9 221.2 19.2 2.3 12.0 60.5 114.8 62.9 22.3 46.8 65.6 44.4 162.0 16.1 17.3 75.1 10.4 122.6 32.9 179.2 76.1 68.8 43.6 49.1 628.6 47.9 43.8 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 20.3 34.2 28.2 22.8 25.1 27.0 38.5 26.8 19.6 32.0 24.9 63.6 349.4 84.7 121.5 9.8 70.5 51.2 76.8 60.3 37.8 67.0 57.1 164.7 77.2 85.7 22.0 31.3 1.3 11.6 92.9 1.9 54.7 0.0 38.4 59.1 29.0 27.4 21.3 12.1 40.8 6.3 69.7 124.4 121.2 112.0 111.7 17.5 116.0 13.9 180.0 17.0 71.8 12.2 16.2 199.0 0.3 1.8 144.1 28.4 10.3 11.3 265.8 0.0 124.1 1.8 86.0 47.1 3.4 15.9 119.4 61.9 20.5 11.4 43.9 0.0 42.1 79.1 1.1 1.9 82.0 78.3 7.9 11.4 17.4 51.0 137.5 VEGFB "VEGFL, VRF" ENSG00000173511 "Vascular endothelial growth factor B" P49765 11 64234584-64239264 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.9;Muller glia cells: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 30.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 30.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 186000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.33e-2)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (2.45e-1)" "unprognostic (4.68e-1)" "unprognostic (5.01e-3)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (1.67e-2)" "unprognostic (8.08e-3)" "unprognostic (2.00e-1)" "unprognostic (4.15e-2)" "unprognostic (4.31e-3)" 209.8 82.0 45.7 12.0 51.3 3.9 151.3 41.8 53.1 103.6 48.2 151.5 12.1 99.9 7.2 50.8 72.5 19.2 253.3 38.7 45.1 84.6 44.0 82.5 14.4 54.8 47.4 82.6 84.9 18.3 104.2 9.8 45.0 92.7 4.7 12.7 57.7 28.5 143.8 77.3 59.5 10.2 44.2 55.9 89.2 17.5 50.6 6.6 83.7 51.5 9.1 118.0 77.5 37.3 15.4 25.9 9.9 28.1 49.7 36.8 12.7 14.7 27.8 13.1 16.0 13.8 31.7 19.8 28.6 14.0 28.8 20.8 15.8 11.5 2.3 20.6 15.1 16.7 33.9 13.3 45.4 4.8 20.1 39.6 12.0 19.6 12.2 33.9 18.4 20.6 20.2 32.5 22.2 31.8 27.4 12.6 7.0 10.9 22.3 32.1 20.5 46.5 11.0 19.5 14.0 46.4 12.4 38.1 57.4 7.6 25.1 5.6 13.0 50.8 30.2 23.1 8.7 90.5 45.5 15.4 41.6 5.3 25.1 0.3 0.2 0.6 0.9 0.0 0.8 3.0 0.8 0.9 0.4 2.4 0.9 1.6 0.0 0.4 0.0 30.5 0.5 0.4 45.7 51.3 41.8 53.1 38.7 45.1 54.8 47.4 45.0 44.2 50.6 37.3 54.1 19.2 32.6 43.8 27.6 12.7 6.7 10.1 2.2 47.9 32.8 65.7 204.9 10.0 7.6 14.7 33.3 9.6 68.3 11.9 39.2 14.8 1.1 24.2 47.7 21.9 53.3 4.4 7.3 12.9 16.8 68.6 5.1 31.6 18.4 62.7 19.6 9.8 51.4 65.6 26.6 12.2 20.3 31.5 21.5 3.5 60.9 50.0 35.6 19.7 17.7 130.6 12.3 29.1 11.8 14.5 7.3 109.1 12.3 11.5 20.3 31.6 8.9 39.6 6.6 47.4 53.7 0.5 1.2 6.4 13.9 8.9 19.0 34.3 12.8 7.5 VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 39.3;Endothelial cells: 22.0;Leydig cells: 13.7;Microglial cells: 36.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 146.5;HBF TERT88: 114.4;hTEC/SVTERT24-B: 116.5;LHCN-M2: 129.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 7.0" "Secreted to blood" NA NA 383000 340000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" 25.0 6.9 2.6 4.2 2.5 0.2 16.7 2.7 2.8 9.7 2.1 4.7 2.4 7.3 1.8 4.0 8.5 6.8 12.7 2.4 2.4 6.7 4.2 16.8 8.0 3.1 2.8 5.9 1.8 2.7 1.5 19.3 2.9 5.1 3.3 1.2 7.4 5.0 3.1 5.1 6.8 6.6 2.6 3.9 3.2 1.4 3.7 1.1 27.7 4.1 3.4 10.3 7.6 2.5 5.9 2.8 1.8 0.0 25.5 25.3 0.0 146.5 87.3 79.2 62.5 0.0 0.7 0.0 0.0 82.7 33.1 4.4 1.3 54.8 114.4 0.1 2.8 0.0 3.8 0.0 13.9 0.0 0.0 27.0 2.5 116.5 80.5 79.3 49.7 0.0 0.0 0.0 129.9 2.1 0.0 0.0 1.3 0.0 47.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 2.3 3.3 0.1 0.7 0.7 0.2 24.2 83.6 9.2 20.8 42.1 0.2 0.0 0.0 34.9 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 2.5 2.7 2.8 2.4 2.4 3.1 2.8 2.9 2.6 3.7 2.5 39.3 3.2 0.0 10.1 0.1 2.4 1.3 3.2 0.0 1.0 3.2 1.7 1.5 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 3.1 8.3 10.9 22.0 0.0 0.0 2.0 0.0 0.0 9.1 0.0 11.0 0.0 8.5 10.0 0.0 0.3 1.7 2.0 0.0 4.1 0.3 2.2 1.2 13.7 0.4 3.6 36.5 0.0 3.4 0.0 1.5 0.6 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.2 0.0 1.9 11.7 0.2 2.0 0.3 2.0 0.0 0.2 1.9 0.0 3.6 VGF "SCG7, SgVII" ENSG00000128564 "VGF nerve growth factor inducible" O15240 7 101162509-101165569 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 1407.4" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 128.3;Horizontal cells: 225.4" "Cancer enriched" "Detected in many" 6 "melanoma: 236.3" "Region enriched" "Detected in all" 6 "hypothalamus: 1407.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 172.0;SK-MEL-30: 511.5;U-2 OS: 85.9;WM-115: 141.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055177, HPA072505" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1270000 3100000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus, Vesicles" "HPA055177: AB_2682728, HPA072505: AB_2686528" "unprognostic (3.04e-2)" "unprognostic (3.45e-1)" "unprognostic (3.19e-3)" "prognostic unfavorable (4.25e-4)" "prognostic unfavorable (3.31e-4)" "unprognostic (1.51e-2)" "unprognostic (2.86e-2)" "unprognostic (1.66e-3)" "unprognostic (2.25e-2)" "unprognostic (8.77e-2)" "unprognostic (3.84e-3)" "unprognostic (3.70e-3)" "unprognostic (9.82e-3)" "unprognostic (3.79e-1)" "unprognostic (7.23e-2)" "unprognostic (4.36e-3)" "unprognostic (2.21e-1)" 2.1 3.1 23.7 0.8 24.8 0.1 0.1 5.5 174.6 0.0 0.0 0.5 0.1 0.7 0.0 0.0 0.0 0.0 0.1 22.7 1407.4 3.6 0.0 0.1 0.0 235.4 69.9 0.1 16.1 0.0 117.0 0.0 158.8 0.1 0.0 2.2 0.0 0.0 0.0 0.8 0.3 0.2 16.6 0.1 1.9 0.9 48.7 0.0 0.6 0.0 0.0 0.0 0.1 27.3 2.2 1.1 1.1 9.5 0.0 0.0 10.3 0.9 0.0 0.0 0.0 2.4 0.9 0.1 3.1 0.0 1.4 1.4 0.5 0.1 0.0 1.0 0.7 0.3 0.0 0.9 0.1 0.6 4.4 0.1 0.2 0.2 0.7 0.0 0.0 0.1 3.7 2.3 0.0 23.4 0.1 2.4 17.6 1.0 2.3 0.8 0.0 0.1 0.3 0.1 14.1 172.0 0.3 0.9 511.5 1.1 0.4 0.3 0.0 0.4 85.9 0.0 2.0 0.1 0.8 4.7 13.5 0.4 141.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 24.8 5.5 174.6 22.7 1407.4 235.4 69.9 158.8 16.6 48.7 27.3 1.7 0.0 0.0 3.6 0.9 1.5 1.0 0.0 1.2 22.0 0.9 0.6 2.9 0.0 0.0 0.0 0.0 1.5 1.0 1.3 29.4 0.3 0.1 0.4 0.4 0.9 128.3 0.0 22.7 0.0 8.4 0.3 3.1 0.5 0.0 1.4 0.0 0.0 0.6 225.4 37.7 4.5 0.0 0.0 0.4 0.6 0.6 0.7 0.0 11.2 0.0 2.1 0.0 4.0 4.8 5.9 2.8 0.0 0.9 4.3 2.7 1.2 0.0 5.0 0.0 0.1 0.8 0.2 4.3 0.6 2.3 1.4 0.5 5.4 2.3 0.6 VILL ENSG00000136059 "Villin like" O15195 3 37988059-38007188 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "intestine: 61.9;stomach 1: 97.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 221.7;Gastric mucus-secreting cells: 192.7;Paneth cells: 139.0;Proximal enterocytes: 165.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 22.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 25.0;OE19: 78.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA035675, HPA035676" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA035675: AB_10671223, HPA035676: " "unprognostic (7.86e-3)" "unprognostic (7.37e-3)" "unprognostic (1.43e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (1.35e-4)" "prognostic favorable (1.75e-4)" "unprognostic (1.69e-1)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.95e-2)" "unprognostic (3.66e-3)" "unprognostic (5.55e-2)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (7.43e-3)" 5.4 3.7 8.7 11.0 9.0 12.6 6.4 6.6 10.6 9.5 6.4 46.8 61.9 5.7 1.5 7.2 6.7 15.7 6.4 8.6 7.8 5.3 1.4 7.7 9.8 8.3 8.4 6.8 3.4 1.2 5.1 4.1 8.0 16.0 26.6 1.2 5.7 4.0 1.2 9.1 61.7 4.1 8.0 11.8 97.5 5.4 8.2 10.2 7.4 1.4 6.3 17.5 7.4 7.2 8.2 0.1 0.2 0.4 2.8 2.2 0.8 2.3 1.9 2.3 2.2 6.1 25.0 3.9 3.5 1.6 0.0 1.9 1.8 0.2 0.5 0.8 0.0 7.3 0.1 0.6 3.4 7.7 9.5 3.3 2.2 2.2 0.0 0.0 4.5 16.1 7.3 2.3 2.6 0.1 12.4 8.7 0.2 78.4 0.0 4.8 0.0 2.0 0.8 9.8 0.1 0.3 0.0 0.5 1.8 0.0 0.7 12.4 2.8 1.0 0.3 3.0 0.0 1.4 3.1 1.2 0.6 10.9 5.0 0.0 3.2 0.0 6.8 2.0 7.4 3.5 4.4 3.9 2.1 4.6 5.6 4.2 0.1 3.4 1.4 3.8 5.8 4.1 8.7 9.0 6.6 10.6 8.6 7.8 8.3 8.4 8.0 8.0 8.2 7.2 4.9 9.6 7.4 10.4 7.2 2.3 5.7 25.5 6.8 0.9 3.3 2.9 1.9 8.6 46.1 0.0 0.0 3.0 13.3 221.7 0.0 3.4 6.2 1.5 2.7 4.5 9.6 6.1 5.5 16.9 3.4 6.7 192.7 1.5 8.2 6.1 5.3 0.3 2.4 1.7 3.0 64.4 14.2 1.9 2.4 19.9 3.7 4.0 1.8 3.7 4.2 28.1 7.2 2.5 1.2 38.7 139.0 2.6 4.4 6.2 165.6 1.6 40.5 0.8 0.0 4.3 7.1 5.4 3.4 3.1 1.4 1.0 8.1 5.6 50.5 33.4 VIP ENSG00000146469 "Vasoactive intestinal peptide" P01282 6 152750797-152759765 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 72.2;lymphoid tissue: 155.5" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 80.6;Melanocytes: 28.4" "Group enriched" "Detected in some" 6 "colorectal cancer: 3.7;pancreatic cancer: 4.3;stomach cancer: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 2.7;TIME: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA017324, CAB018649, HPA072701, CAB079780" Supported Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 122000 "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "CAB018649: AB_2304501, CAB079780: , HPA017324: AB_1858754, HPA072701: AB_2686550" "unprognostic (9.58e-2)" "unprognostic (2.29e-2)" "unprognostic (2.60e-2)" "unprognostic (1.13e-1)" "unprognostic (3.34e-2)" "unprognostic (3.33e-2)" "unprognostic (2.48e-2)" "unprognostic (7.21e-2)" "unprognostic (2.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (3.62e-1)" "unprognostic (2.92e-3)" "unprognostic (7.47e-2)" "unprognostic (1.94e-1)" "unprognostic (1.30e-1)" "unprognostic (5.90e-2)" 2.7 12.2 5.5 155.5 7.9 0.1 1.9 4.9 10.9 1.8 4.6 72.2 16.6 1.2 0.4 4.3 1.5 3.7 4.3 7.3 28.7 2.5 1.1 3.4 0.4 6.9 40.0 0.8 8.3 0.3 0.8 0.6 7.7 2.7 61.4 1.0 0.5 0.5 1.4 0.4 45.8 41.6 4.8 9.7 22.2 1.0 11.9 0.1 2.3 1.7 0.1 1.6 9.4 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 7.9 4.9 10.9 7.3 28.7 6.9 40.0 7.7 4.8 11.9 5.9 2.5 0.0 0.0 3.3 0.2 0.4 0.0 0.0 0.0 1.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 2.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 80.6 0.0 0.0 0.3 0.0 6.5 0.0 0.0 28.4 4.7 0.0 0.0 0.0 2.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VIPR2 "VPAC2, VPAC2R" ENSG00000106018 "Vasoactive intestinal peptide receptor 2" P41587 7 159028175-159144867 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 20.6;Excitatory neurons: 15.2;Muller glia cells: 38.9;Oligodendrocyte precursor cells: 49.8;Rod photoreceptor cells: 45.1" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 17 "plasmacytoid DC: 12.3" "Lineage enriched" "Detected in single" 17 "dendritic cells: 12.3" "Cell line enhanced" "Detected in some" "HeLa: 6.6;HMC-1: 9.0;MOLT-4: 12.9;U-266/70: 40.5" "Region enhanced" "Detected in many" "olfactory bulb: 27.1" "Low region specificity" "Detected in many" HPA062707 Approved Approved "Focal adhesion sites" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Focal adhesion sites" "HPA062707: AB_2684842" "unprognostic (3.65e-2)" "unprognostic (2.13e-2)" "unprognostic (4.26e-2)" "unprognostic (2.04e-2)" "unprognostic (6.31e-2)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (8.58e-2)" "unprognostic (2.32e-2)" "unprognostic (1.02e-1)" "unprognostic (9.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (8.89e-2)" 12.5 0.8 2.2 0.9 1.6 0.4 2.5 0.6 6.9 16.8 1.4 13.8 1.7 6.8 12.2 1.4 4.5 2.5 16.4 2.1 2.0 1.1 0.4 0.6 1.1 2.2 0.8 12.0 17.5 0.9 2.7 5.7 2.6 9.2 1.1 6.5 0.3 20.5 7.4 0.7 4.8 4.2 2.1 0.8 8.6 2.2 1.3 8.2 0.2 5.4 0.4 6.8 11.2 2.9 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.0 0.2 12.9 0.1 1.0 0.0 0.0 3.2 0.1 0.7 0.0 0.0 2.8 2.3 0.1 0.2 0.0 0.3 0.0 0.7 0.0 0.0 0.4 0.0 0.0 40.5 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 12.3 0.0 0.1 2.2 1.6 0.6 6.9 2.1 2.0 2.2 0.8 2.6 2.1 1.3 2.9 0.8 0.0 0.0 2.9 0.7 0.6 2.9 0.0 1.8 1.7 1.6 1.8 7.5 0.0 0.0 0.0 2.1 0.0 20.6 0.0 0.0 0.0 1.3 0.4 6.9 0.4 0.0 0.0 15.2 6.7 0.0 10.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 0.3 1.9 10.2 0.5 1.8 1.9 0.0 38.9 4.1 49.8 0.3 0.8 0.0 2.6 2.4 2.0 0.0 0.5 0.0 45.1 0.0 2.9 5.6 3.6 10.2 0.1 0.0 0.0 3.8 0.1 0.0 0.3 VIT ENSG00000205221 Vitrin Q6UXI7 2 36696690-36814792 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.4;tongue: 41.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 68.3;Fibroblasts: 58.8;Granulosa cells: 45.1;Leydig cells: 115.2;Skeletal myocytes: 45.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 10 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "ASC diff: 33.6;ASC TERT1: 65.2;BJ: 32.9;fHDF/TERT166: 112.3;SuSa: 62.2;THP-1: 35.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.34e-4)" "unprognostic (4.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.20e-1)" "unprognostic (7.78e-3)" "unprognostic (8.32e-2)" "unprognostic (1.81e-1)" "unprognostic (3.08e-1)" "unprognostic (3.35e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (3.66e-6)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (3.62e-3)" "unprognostic (1.41e-2)" 35.4 0.9 0.2 0.5 0.5 0.9 15.4 0.8 0.9 6.0 0.4 3.9 0.4 1.0 0.6 8.7 7.9 2.3 18.6 0.3 0.1 0.2 0.0 1.2 2.3 0.1 0.1 28.7 1.0 0.6 3.1 2.2 0.1 7.0 1.5 0.0 11.6 2.3 12.5 12.7 2.7 0.2 0.0 0.1 4.7 3.0 0.3 1.0 8.9 41.1 2.2 15.0 14.6 0.2 0.0 0.0 0.0 0.0 33.6 65.2 0.0 32.9 7.7 10.4 4.3 0.0 0.0 0.0 0.0 112.3 0.1 0.2 6.2 0.0 6.9 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.3 1.6 0.0 0.0 0.0 2.5 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.7 0.0 62.2 0.0 35.6 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 2.5 2.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.5 0.8 0.9 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.2 4.1 0.0 0.0 0.7 0.0 4.2 0.9 0.0 68.3 0.0 0.2 10.0 3.2 0.0 0.0 0.0 0.0 10.6 0.9 0.3 0.0 0.0 1.2 0.4 0.4 1.1 0.0 0.0 1.8 0.0 11.0 58.8 0.0 0.0 0.0 45.1 0.4 0.0 1.1 0.0 0.7 0.4 0.0 0.0 3.5 2.7 115.2 0.5 7.2 20.6 0.0 0.0 4.1 0.5 0.3 0.0 0.1 23.3 0.8 0.1 0.0 0.0 0.0 0.0 6.6 45.2 6.1 1.1 0.6 1.6 3.4 4.2 1.1 0.1 0.3 0.2 VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 454.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 749.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 638.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" 99.4 107.6 56.0 38.4 60.4 55.2 87.0 60.3 73.5 111.0 64.9 97.0 44.2 109.9 87.2 51.8 90.8 58.9 99.1 57.4 59.3 122.7 454.9 77.4 35.8 64.4 59.5 115.1 168.0 51.3 115.7 45.6 63.8 76.3 41.1 23.0 92.4 69.8 34.4 81.1 82.3 84.7 59.9 62.2 88.1 55.6 68.5 35.0 76.3 32.2 32.6 100.6 88.0 64.8 73.6 187.7 57.2 165.4 638.0 389.6 68.2 269.0 229.3 128.9 218.5 79.0 83.3 54.9 141.6 331.6 87.2 66.2 79.4 103.5 139.5 81.9 204.8 52.5 239.9 378.2 103.1 104.1 74.1 225.0 54.2 173.4 146.6 336.8 141.0 78.2 70.3 130.6 253.6 271.1 74.4 205.9 106.8 98.0 175.9 132.7 160.3 286.8 127.7 61.8 119.5 146.9 118.7 84.2 137.8 91.2 138.3 123.9 126.8 171.1 61.5 159.6 101.9 76.1 80.2 50.7 445.8 174.5 90.8 77.0 127.5 196.2 118.1 94.7 116.8 91.7 116.7 119.4 127.6 102.6 102.9 101.4 104.0 84.2 98.2 157.4 143.1 112.8 56.0 60.4 60.3 73.5 57.4 59.3 64.4 59.5 63.8 59.9 68.5 64.8 95.1 57.7 51.0 5.9 30.6 84.6 68.0 157.0 10.8 12.3 93.3 117.3 20.9 141.5 64.3 108.5 8.4 85.7 48.1 34.3 62.6 204.2 6.1 25.8 83.7 89.5 67.1 32.4 8.8 129.4 293.6 132.8 10.7 48.8 55.3 60.3 118.9 749.9 184.1 10.1 7.5 44.2 46.8 80.1 94.3 13.9 158.1 66.9 115.6 5.6 107.4 68.8 51.5 6.6 17.6 103.8 28.2 172.3 29.5 59.5 152.9 204.6 33.4 19.3 59.2 78.4 99.8 30.6 34.2 10.7 112.0 39.5 39.7 82.4 49.0 55.2 VLDLR "CARMQ1, CHRMQ1, VLDLRCH" ENSG00000147852 "Very low density lipoprotein receptor" P98155 9 2621182-2660056 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 77.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 78.1;Cone photoreceptor cells: 104.3;Oligodendrocytes: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 6.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.3" "Cell line enhanced" "Detected in many" "BEWO: 22.3;JURKAT: 20.5;THP-1: 33.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032462, HPA051312" Uncertain Uncertain "Vesicles,Cytokinetic bridge,Centriolar satellite" Yes NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Cytokinetic bridge, Centriolar satellite" "CAB032462: AB_2216805, HPA051312: " "unprognostic (5.31e-2)" "unprognostic (2.65e-1)" "unprognostic (6.92e-2)" "prognostic favorable (5.95e-4)" "unprognostic (1.15e-1)" "unprognostic (2.67e-2)" "unprognostic (2.48e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-1)" "unprognostic (3.00e-2)" "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (6.75e-2)" "unprognostic (1.48e-2)" "unprognostic (1.93e-1)" "unprognostic (1.80e-2)" "unprognostic (4.34e-2)" 15.7 16.3 2.7 2.2 6.4 0.8 8.5 5.3 4.2 10.3 6.4 6.6 0.5 9.6 3.2 19.2 13.8 2.9 43.7 3.2 5.3 10.6 3.1 10.7 0.7 7.7 5.6 77.5 27.4 19.5 6.5 5.9 5.9 6.6 2.0 12.3 11.6 2.0 26.2 5.3 1.9 6.8 4.0 5.5 9.0 6.0 4.9 0.8 11.6 11.7 1.7 12.5 10.4 9.8 0.1 0.8 14.3 0.4 1.5 0.5 22.3 7.0 2.2 1.7 4.3 3.6 0.3 0.0 6.4 2.8 0.6 0.3 3.4 5.6 4.5 9.7 2.4 0.1 1.6 1.8 1.9 9.2 1.7 1.5 3.3 0.7 0.1 7.6 0.7 20.5 0.0 17.4 1.1 0.9 1.1 1.1 9.9 1.5 0.9 0.1 0.4 0.0 6.4 0.4 2.5 2.4 0.6 0.6 10.4 7.5 0.3 33.3 0.3 2.8 4.5 0.1 3.3 14.1 6.1 2.6 14.7 8.2 0.6 0.0 0.0 6.3 0.2 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 2.7 6.4 5.3 4.2 3.2 5.3 7.7 5.6 5.9 4.0 4.9 9.8 4.2 16.0 8.8 1.0 0.1 2.7 1.2 18.7 4.6 23.8 4.3 3.9 78.1 1.5 9.7 5.5 104.3 13.2 1.6 9.8 1.9 11.3 5.7 8.6 6.1 3.6 10.9 0.0 8.3 10.3 29.0 17.2 3.1 19.3 0.0 5.7 2.2 2.8 2.3 11.8 10.9 1.4 24.4 1.0 1.1 2.8 7.8 0.6 10.6 2.8 1.0 3.9 0.0 8.0 39.1 8.6 4.3 10.9 0.5 5.1 0.0 8.0 11.9 32.5 0.0 2.7 9.4 8.2 6.4 5.0 2.0 3.4 1.7 15.9 1.3 6.0 VMO1 ENSG00000182853 "Vitelline membrane outer layer 1 homolog" Q7Z5L0 17 4785285-4786433 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.8;pituitary gland: 27.7" "Group enriched" "Detected in many" 4 "Club cells: 923.5;monocytes: 857.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "non-classical monocyte: 111.9" "Lineage enriched" "Detected in many" 9 "monocytes: 111.9" "Cell line enhanced" "Detected in some" "A549: 3.0;MCF7: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA023038 Uncertain "Secreted to blood" NA NA 2900000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA023038: AB_10964632" "unprognostic (1.30e-1)" "unprognostic (5.71e-2)" "unprognostic (1.65e-3)" "unprognostic (9.09e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (5.58e-3)" "unprognostic (1.20e-1)" "unprognostic (1.65e-1)" "unprognostic (7.41e-2)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.34e-6)" "unprognostic (1.10e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-1)" "unprognostic (2.69e-1)" 5.1 2.5 4.5 7.0 4.5 2.4 2.3 4.7 6.5 3.1 6.7 2.1 4.9 1.6 0.1 1.7 1.6 3.4 2.3 4.5 5.2 5.5 10.4 8.9 2.0 6.1 4.7 1.0 2.3 13.3 27.7 2.3 5.1 3.0 0.8 0.5 5.2 1.6 10.1 2.0 5.6 0.9 5.3 21.8 1.6 0.7 5.1 2.1 1.4 1.5 0.5 4.7 2.5 6.1 0.2 3.0 0.3 1.8 0.3 0.7 0.3 0.6 1.1 0.1 0.3 0.9 1.1 0.1 0.0 0.1 0.2 0.5 0.0 0.4 0.2 2.2 0.4 0.1 0.6 0.8 0.6 0.0 1.3 0.5 0.4 0.1 0.4 0.6 0.0 0.4 0.3 0.4 0.6 3.9 0.0 0.9 0.7 0.7 1.3 0.7 1.5 0.3 0.0 0.7 0.2 0.4 0.2 0.2 0.3 0.2 1.2 0.1 0.3 1.2 0.1 0.3 0.2 0.0 0.3 0.0 0.5 0.6 0.9 0.1 0.2 0.0 0.0 9.7 0.0 0.0 0.0 0.0 12.3 0.1 0.0 0.1 0.0 0.4 111.9 0.0 0.0 3.7 4.5 4.5 4.7 6.5 4.5 5.2 6.1 4.7 5.1 5.3 5.1 6.1 2.8 3.2 7.7 1.0 2.8 8.5 13.4 217.2 0.6 6.7 2.8 3.7 0.9 1.5 923.5 0.0 0.0 0.4 0.8 1.1 1.9 0.9 8.2 0.4 0.8 5.2 1.2 3.2 0.5 1.5 0.3 2.5 0.0 0.4 14.0 0.3 79.6 3.3 16.2 0.0 0.9 1.0 101.7 59.8 210.9 40.3 0.3 70.8 5.4 1.0 857.9 1.0 0.0 0.0 0.6 1.5 0.3 1.2 0.7 11.2 4.3 2.4 158.4 2.9 13.1 1.3 45.5 0.6 1.5 0.8 7.2 0.3 2.0 0.5 1.3 14.2 VNN1 Tiff66 ENSG00000112299 "Vanin 1" O95497 6 132680849-132714055 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "gallbladder: 89.2;intestine: 136.3;liver: 218.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 50.1;Ductal cells: 244.2;Hepatocytes: 70.6;Pancreatic endocrine cells: 98.0;Proximal enterocytes: 61.7" "Cancer enhanced" "Detected in many" "liver cancer: 41.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "classical monocyte: 13.7;non-classical monocyte: 11.9" "Group enriched" "Detected in many" 80 "dendritic cells: 5.0;granulocytes: 8.5;monocytes: 13.7" "Cell line enhanced" "Detected in some" "A-431: 2.5;CAPAN-2: 2.5;EFO-21: 8.7;HBEC3-KT: 2.3;LHCN-M2: 2.5" "Region enhanced" "Detected in single" "white matter: 2.4" "Not detected" "Not detected" "HPA046103, HPA064145" Approved Approved Vesicles "Intracellular and membrane" NA NA 980000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA046103: , HPA064145: AB_2685197" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (9.95e-2)" "unprognostic (1.35e-3)" "unprognostic (6.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (4.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (2.26e-2)" "unprognostic (4.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.34e-1)" 2.7 0.6 0.3 3.1 0.6 9.4 1.1 0.5 1.5 1.0 0.0 6.2 136.3 8.9 0.2 0.6 2.6 89.2 0.6 0.2 0.3 21.7 218.7 4.7 2.5 0.6 0.3 0.3 1.4 0.1 0.1 2.7 1.2 0.3 1.8 1.0 2.3 0.2 0.3 0.9 79.5 0.9 0.2 10.1 1.5 0.5 0.5 0.6 0.4 1.1 2.5 1.6 0.7 0.9 2.5 0.0 0.3 0.1 0.0 0.7 0.5 0.2 0.2 0.0 0.0 0.0 2.5 0.1 8.7 0.0 0.4 0.0 0.0 2.3 0.6 0.0 0.0 0.1 0.1 1.4 1.3 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.1 1.1 0.5 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.6 0.0 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.3 3.0 13.7 0.0 0.0 8.0 0.0 0.0 0.0 0.0 5.0 0.1 0.0 0.0 8.5 0.0 11.9 0.2 0.0 3.8 0.3 0.6 0.5 1.5 0.2 0.3 0.6 0.3 1.2 0.2 0.5 0.9 0.0 0.0 3.0 0.0 0.3 1.3 0.2 14.9 0.0 0.0 1.2 0.4 0.2 50.1 11.4 1.8 0.0 0.1 0.2 12.5 0.0 244.2 0.0 7.6 4.1 0.2 0.0 0.0 0.0 19.4 0.1 0.3 4.6 39.6 0.0 0.0 1.1 70.6 18.1 0.0 0.0 11.2 22.4 12.0 3.9 0.0 0.0 23.1 0.0 0.0 17.6 0.0 0.0 0.0 0.0 98.0 1.6 0.0 0.5 6.6 61.7 21.9 16.0 0.0 0.0 0.4 1.1 0.1 0.0 0.1 0.1 0.1 0.5 0.0 2.0 14.7 VNN2 "FOAP-4, GPI-80" ENSG00000112303 "Vanin 2" O95498 6 132743870-132763459 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.6;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "Ductal cells: 63.6;Ionocytes: 22.4;Macrophages: 41.1;monocytes: 57.5;Respiratory ciliated cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 477.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 477.4" "Cell line enriched" "Detected in some" 7 "Daudi: 59.7" "Low region specificity" "Detected in some" NA NA 240000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.13e-1)" "unprognostic (1.15e-1)" "unprognostic (9.60e-3)" "unprognostic (5.71e-2)" "unprognostic (2.14e-1)" "unprognostic (5.61e-3)" "unprognostic (1.98e-3)" "unprognostic (4.38e-1)" "unprognostic (3.07e-1)" "unprognostic (3.46e-1)" "unprognostic (2.84e-1)" "unprognostic (8.30e-2)" "prognostic unfavorable (2.72e-7)" "unprognostic (1.62e-1)" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (5.45e-2)" 21.7 2.7 0.6 23.9 0.9 31.6 1.3 0.7 2.8 4.3 1.4 3.8 2.4 1.3 0.4 4.1 5.3 22.5 2.3 0.5 0.7 2.4 10.1 22.5 39.0 1.5 1.0 1.5 4.3 0.7 0.9 20.7 1.7 1.8 3.0 0.1 1.5 0.9 0.6 0.3 4.6 6.3 0.8 56.6 7.3 0.6 1.0 11.7 1.2 7.9 42.0 17.8 1.2 1.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 59.7 1.1 0.0 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 1.1 1.4 0.0 0.0 11.6 65.2 0.3 24.6 14.5 10.3 40.3 8.4 29.0 14.1 32.2 27.0 39.4 477.4 36.1 9.9 2.6 6.1 40.4 0.6 0.9 0.7 2.8 0.5 0.7 1.5 1.0 1.7 0.8 1.0 1.0 0.2 0.0 6.7 0.0 11.0 0.0 0.5 4.3 0.0 0.0 0.2 0.0 1.5 7.2 11.8 0.0 0.0 0.8 10.9 0.1 0.0 63.6 0.0 0.3 0.0 1.4 0.0 1.3 0.2 0.4 0.2 1.9 13.3 0.2 5.1 0.1 3.3 1.0 13.9 0.0 0.0 0.0 22.4 18.6 1.0 0.0 0.0 41.1 0.0 1.9 57.5 0.3 20.6 0.0 0.1 3.6 0.0 0.0 2.7 8.0 0.0 0.6 25.4 0.1 6.6 2.5 1.2 0.1 0.0 0.1 0.0 1.4 10.9 6.5 0.2 14.5 VNN3 HSA238982 ENSG00000093134 "Vanin 3" Q9NY84 6 132722787-132736935 "Enzymes, Metabolic proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 34.9;liver: 34.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 20.7;Club cells: 42.5;Gastric mucus-secreting cells: 15.8;Respiratory ciliated cells: 86.1" "Cancer enriched" "Detected in some" 4 "liver cancer: 3.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 4 "neutrophil: 76.2" "Lineage enriched" "Detected in many" 33 "granulocytes: 76.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 150000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (3.20e-2)" "unprognostic (2.70e-1)" "unprognostic (7.92e-3)" "unprognostic (1.71e-2)" "unprognostic (3.05e-3)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.01e-1)" "unprognostic (2.42e-2)" "unprognostic (7.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (5.84e-8)" "unprognostic (1.25e-2)" "unprognostic (1.52e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" 1.2 0.1 0.1 2.2 0.1 34.9 0.2 0.1 0.5 1.6 0.2 0.1 0.0 0.1 0.0 0.8 1.9 1.0 0.4 0.1 0.1 0.3 34.7 4.5 0.4 0.1 0.1 0.0 0.1 0.0 0.1 1.3 0.2 0.3 0.0 0.0 1.0 0.1 0.1 0.2 0.2 0.2 0.1 5.5 0.4 0.1 0.2 0.4 0.1 1.1 0.4 0.5 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.2 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.1 20.7 0.0 0.0 0.2 0.0 0.4 0.0 42.5 0.0 0.0 0.0 0.1 0.2 0.0 3.7 0.2 2.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.8 15.8 1.7 0.0 0.0 0.4 10.0 0.1 0.0 0.0 0.0 6.1 5.8 0.0 0.2 0.0 3.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 2.0 0.0 0.1 86.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.0 0.2 0.2 0.3 4.1 VPREB1 "CD179A, VpreB" ENSG00000169575 "V-set pre-B cell surrogate light chain 1" P12018 22 22244780-22245515 "CD markers, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "bone marrow: 29.8" "Cell type enhanced" "Detected in single" "NK-cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 5.7;naive B-cell: 5.3" "Lineage enriched" "Detected in many" 4 "B-cells: 5.7" "Group enriched" "Detected in some" 11 "Daudi: 9.4;MOLT-4: 19.8;RPMI-8226: 5.4" "Not detected" "Not detected" HPA055886 Approved "Intracellular and membrane" NA NA 62000 "Cluster 37: B-cells - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "HPA055886: AB_2682956" 0.0 0.0 0.0 0.0 0.0 29.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 VPREB3 8HS20 ENSG00000128218 "V-set pre-B cell surrogate light chain 3" Q9UKI3 22 23752743-23754425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;intestine: 72.5;lymphoid tissue: 118.5" "Cell type enriched" "Detected in some" 12 "B-cells: 287.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 709 "memory B-cell: 753.3;naive B-cell: 803.7" "Lineage enriched" "Detected in many" 732 "B-cells: 803.7" "Group enriched" "Detected in some" 46 "Daudi: 263.3;REH: 309.9;U-698: 85.2" "Low region specificity" "Detected in single" HPA003041 Supported "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA003041: AB_1080577" "unprognostic (2.06e-3)" "unprognostic (4.75e-3)" "unprognostic (2.35e-1)" "unprognostic (2.39e-2)" "unprognostic (1.21e-2)" "unprognostic (2.75e-2)" "unprognostic (4.79e-2)" "unprognostic (6.63e-3)" "unprognostic (9.15e-2)" "unprognostic (1.38e-2)" "unprognostic (4.93e-2)" "unprognostic (4.84e-2)" "unprognostic (8.44e-2)" "unprognostic (4.19e-2)" "unprognostic (1.18e-1)" "unprognostic (2.87e-1)" "unprognostic (4.12e-1)" 1.7 21.1 2.0 41.3 2.0 25.8 0.4 2.6 3.8 0.3 2.6 3.9 1.7 1.1 51.5 1.2 0.3 2.7 1.1 1.7 2.0 1.6 1.9 0.8 112.4 2.1 2.1 0.1 0.5 0.6 2.5 0.2 2.1 1.6 3.7 2.2 2.5 0.3 1.6 0.6 72.5 0.3 1.9 60.3 6.1 0.6 2.9 7.9 1.7 0.5 118.5 6.2 0.3 1.8 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.6 263.3 0.3 0.2 0.0 0.1 0.5 0.2 0.1 0.6 2.8 0.1 0.0 0.2 0.2 0.3 0.1 1.1 0.7 0.0 0.0 0.0 0.0 0.4 0.4 1.1 0.0 1.3 0.5 1.0 0.3 0.3 1.1 309.9 0.5 4.7 0.1 0.1 0.7 1.0 0.3 0.7 3.5 0.2 0.6 0.4 1.2 0.0 0.5 0.9 0.0 1.3 0.3 85.2 0.0 0.5 0.3 0.9 0.7 0.6 0.4 0.3 0.4 753.3 0.4 0.5 0.7 803.7 0.5 0.5 1.0 0.4 0.7 0.6 1.0 17.5 2.0 2.0 2.6 3.8 1.7 2.0 2.1 2.1 2.1 1.9 2.9 1.8 0.1 0.0 0.5 0.3 287.8 0.4 0.8 0.6 0.6 4.5 0.3 0.5 0.9 1.5 0.8 0.0 2.1 0.0 5.4 1.1 1.9 0.1 0.3 0.1 0.8 0.1 5.4 2.7 0.2 0.0 0.0 1.5 1.5 0.3 0.0 0.7 1.1 1.0 0.3 0.0 0.2 0.6 2.0 0.3 0.8 0.2 0.0 1.2 5.4 0.0 0.7 0.8 2.1 0.5 0.1 0.1 0.3 0.0 22.6 0.2 1.5 2.4 0.0 2.1 0.0 0.5 0.4 0.1 0.2 0.4 0.1 0.0 3.5 0.1 0.7 0.3 VPS35 "FLJ10752, MEM3, PARK17" ENSG00000069329 "VPS35 retromer complex component" Q96QK1 16 46656132-46689518 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040802 Supported Supported Endosomes,Lysosomes NA NA 500000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Endosomes, Lysosomes" "HPA040802: AB_2677142" "unprognostic (1.11e-2)" "unprognostic (8.70e-2)" "prognostic favorable (7.74e-4)" "unprognostic (4.75e-2)" "unprognostic (1.90e-1)" "unprognostic (5.67e-3)" "prognostic unfavorable (2.10e-6)" "unprognostic (5.32e-2)" "unprognostic (1.49e-1)" "unprognostic (2.29e-2)" "unprognostic (3.33e-3)" "unprognostic (2.49e-1)" "prognostic favorable (9.75e-5)" "unprognostic (3.68e-3)" "unprognostic (2.43e-1)" "unprognostic (1.34e-1)" "unprognostic (6.89e-3)" 5.4 4.2 2.9 3.0 3.0 9.5 4.6 2.6 3.2 4.2 2.8 4.2 1.9 4.3 1.9 4.7 4.0 1.4 6.1 3.0 2.5 3.7 1.7 4.1 2.9 3.0 2.4 4.7 4.4 5.2 3.3 2.1 3.2 3.0 1.8 4.1 4.5 2.4 4.6 6.1 4.9 1.7 2.1 4.2 4.5 2.7 2.8 3.9 2.7 2.7 1.8 4.5 4.2 3.4 3.2 5.0 4.1 2.8 6.5 7.3 2.1 3.8 5.4 6.4 3.7 4.3 2.7 4.2 2.3 6.5 3.3 3.9 7.5 7.5 9.1 1.6 6.4 3.9 3.8 3.0 5.4 5.2 5.8 5.8 5.5 7.3 4.5 6.3 6.6 6.0 3.1 1.8 6.5 2.9 4.0 5.0 1.4 3.0 6.6 5.4 5.4 5.2 5.2 4.4 1.8 2.1 4.1 3.2 1.8 4.5 1.9 2.6 3.9 1.9 1.9 4.3 2.7 2.3 3.2 4.9 3.4 4.0 1.3 1.8 1.3 1.3 0.7 1.7 0.7 0.8 0.7 0.6 1.5 1.0 1.0 0.7 1.5 0.8 2.3 0.6 1.1 1.1 2.9 3.0 2.6 3.2 3.0 2.5 3.0 2.4 3.2 2.1 2.8 3.4 65.9 51.3 59.4 20.5 84.3 72.5 80.0 98.6 72.8 56.5 77.9 75.9 102.9 57.2 83.4 68.0 60.5 134.5 44.9 65.9 54.8 111.7 111.2 136.4 92.3 63.3 80.8 52.6 43.1 72.5 102.2 70.1 88.7 88.4 72.2 211.1 54.7 40.2 123.4 45.4 42.5 79.7 107.8 108.3 87.9 32.4 77.9 113.6 46.2 30.0 153.0 71.4 45.3 28.6 31.3 101.1 101.9 72.2 41.7 77.0 164.6 103.7 188.9 82.6 46.0 57.5 88.9 207.9 118.0 101.5 87.7 113.1 51.5 95.9 97.6 84.5 VPS37A "FLJ32642, HCRP1, PQBP2, SPG53" ENSG00000155975 "VPS37A subunit of ESCRT-I" Q8NEZ2 8 17246931-17302427 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024705, HPA024781" Supported Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Centrosome, Cytosol" "HPA024705: AB_10601776, HPA024781: AB_10602100" "unprognostic (8.28e-2)" "unprognostic (1.84e-1)" "unprognostic (9.39e-3)" "unprognostic (3.91e-1)" "unprognostic (2.10e-1)" "unprognostic (6.31e-2)" "unprognostic (5.88e-3)" "unprognostic (2.28e-2)" "unprognostic (1.43e-1)" "unprognostic (3.17e-1)" "unprognostic (1.02e-1)" "unprognostic (2.88e-1)" "unprognostic (5.06e-2)" "unprognostic (1.98e-2)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (2.18e-1)" 18.9 19.4 11.9 14.8 15.1 15.4 18.5 28.7 17.5 21.1 5.0 16.8 20.9 19.4 14.3 20.2 13.7 16.8 36.2 10.1 13.6 25.0 27.8 16.2 14.2 11.2 12.5 18.4 17.5 33.8 12.4 29.7 12.1 20.2 17.2 55.0 12.5 23.2 39.4 14.7 17.5 24.4 10.0 12.3 14.5 32.3 12.2 17.5 18.9 31.2 15.2 25.1 15.0 18.4 17.2 27.3 24.0 21.7 51.8 41.5 25.8 60.8 50.2 53.9 45.9 17.6 16.2 14.6 31.6 48.7 50.1 16.7 27.2 26.4 63.8 15.1 7.8 26.5 13.7 20.2 59.7 11.3 25.1 39.7 50.2 50.4 51.5 38.0 38.7 22.7 20.2 36.8 57.7 11.7 32.0 26.9 23.4 38.2 14.2 15.4 26.5 17.6 45.8 23.4 27.1 14.4 23.8 23.9 37.9 47.1 15.6 22.2 33.4 33.1 16.7 47.6 32.0 12.0 25.0 17.2 37.5 19.9 33.8 34.0 17.2 16.5 13.9 13.1 17.1 10.5 13.4 13.6 13.4 10.8 12.0 14.8 17.6 24.5 12.4 11.8 13.3 14.1 11.9 15.1 28.7 17.5 10.1 13.6 11.2 12.5 12.1 10.0 12.2 18.4 31.8 16.0 15.6 19.6 21.2 39.5 32.7 33.1 18.8 26.4 19.3 13.5 40.7 14.3 25.8 7.3 58.4 36.1 20.5 15.8 37.2 29.3 93.2 20.9 29.0 24.6 18.0 26.1 32.4 15.5 59.2 27.0 15.8 28.4 9.5 16.8 24.3 23.1 44.6 21.9 30.7 16.6 30.5 17.5 22.7 39.6 25.7 25.3 21.4 20.6 22.4 25.8 15.5 24.1 34.0 31.2 13.1 25.9 21.5 50.6 27.8 48.8 18.8 60.2 26.3 21.5 36.6 111.6 43.4 22.5 37.8 113.0 22.7 17.1 14.6 52.6 VPS51 "ANG2, ANG3, C11orf2, C11orf3, FFR" ENSG00000149823 "VPS51 subunit of GARP complex" Q9UID3 11 65089324-65111862 "Disease related genes, Predicted intracellular proteins" "Lipid transport, Protein transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039650, HPA061447" Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 50: Non-specific - Ribosome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" Nucleoli "HPA039650: AB_10673147, HPA061447: AB_2684521" "unprognostic (2.36e-2)" "unprognostic (7.58e-2)" "unprognostic (8.35e-2)" "unprognostic (1.56e-1)" "unprognostic (2.11e-2)" "unprognostic (1.64e-1)" "unprognostic (9.72e-2)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (2.03e-3)" "unprognostic (1.56e-1)" "prognostic favorable (2.41e-9)" "unprognostic (7.77e-3)" "unprognostic (4.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.18e-1)" 48.5 37.8 19.0 34.9 23.1 60.9 46.6 22.0 30.7 45.6 20.4 55.4 52.9 54.4 7.3 42.5 46.1 20.3 45.3 22.5 15.5 33.7 36.2 34.2 48.6 18.5 18.6 83.8 120.3 37.4 28.6 22.2 20.2 38.1 25.1 20.3 65.5 27.7 84.2 71.2 49.7 22.7 14.3 40.9 70.3 28.4 17.2 46.7 39.7 42.9 32.5 45.2 38.1 21.5 71.8 74.5 35.7 44.4 15.5 38.5 72.1 27.5 53.2 52.6 38.8 55.2 88.7 118.0 76.1 51.4 27.3 60.0 37.9 59.3 19.2 69.6 62.1 72.5 72.6 55.1 51.3 77.1 65.0 66.8 39.9 39.0 32.1 41.6 58.4 55.0 73.6 82.9 21.7 95.1 105.8 83.0 59.8 30.7 61.5 67.5 17.5 150.7 36.2 76.2 61.5 87.8 20.7 110.9 71.8 21.0 93.7 39.1 48.1 35.2 32.0 45.4 39.7 115.7 92.2 68.9 39.9 28.0 26.3 10.6 15.0 15.4 17.9 15.8 21.2 22.4 25.2 27.1 22.1 21.2 23.3 20.7 8.0 30.6 16.0 19.1 17.7 18.3 19.0 23.1 22.0 30.7 22.5 15.5 18.5 18.6 20.2 14.3 17.2 21.5 49.8 19.2 47.7 18.9 77.3 49.1 66.3 46.0 58.6 64.7 76.5 67.8 5.8 44.3 27.8 31.3 29.2 78.4 73.7 156.5 62.6 49.2 77.5 25.6 35.0 46.5 95.8 50.5 21.8 120.5 79.4 38.8 45.9 34.4 37.5 47.3 55.3 52.5 45.5 67.3 24.1 110.0 32.6 54.0 30.6 222.4 53.4 36.1 49.8 15.9 71.3 65.9 89.6 21.6 28.0 51.2 144.4 54.5 66.4 45.1 158.7 75.9 16.1 52.5 26.3 49.3 44.4 40.3 31.4 52.3 54.8 115.3 64.0 61.5 170.5 51.0 VPS8 "FLJ32099, KIAA0804" ENSG00000156931 "VPS8 subunit of CORVET complex" Q8N3P4 3 184812143-185052614 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 154.1;Granulosa cells: 124.3;Inhibitory neurons: 132.2;Oligodendrocytes: 149.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036871 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane" "HPA036871: AB_10672103" "unprognostic (4.36e-2)" "unprognostic (3.97e-3)" "unprognostic (1.53e-1)" "unprognostic (7.95e-2)" "unprognostic (5.11e-2)" "unprognostic (4.43e-2)" "unprognostic (1.27e-3)" "unprognostic (1.74e-1)" "unprognostic (3.21e-2)" "unprognostic (5.98e-3)" "unprognostic (1.98e-1)" "unprognostic (8.82e-2)" "unprognostic (4.74e-2)" "unprognostic (3.15e-1)" "unprognostic (2.56e-1)" "unprognostic (8.10e-3)" "unprognostic (4.97e-2)" 10.9 9.6 18.7 10.0 22.1 23.2 10.6 24.2 24.0 12.7 29.1 11.4 8.3 12.3 16.3 10.1 9.0 11.1 19.6 20.4 23.6 10.6 8.5 10.7 10.5 25.1 21.4 14.3 8.9 15.8 16.3 12.1 26.3 10.9 14.7 16.4 7.9 10.1 28.6 12.9 9.3 12.9 17.1 13.3 13.0 16.9 26.1 11.6 14.9 15.3 10.7 10.4 10.3 36.4 18.0 10.7 15.9 15.9 32.5 28.8 10.6 17.7 18.8 12.3 17.0 13.6 9.0 19.1 29.3 26.9 50.4 20.8 17.3 21.0 23.6 34.8 15.4 20.4 13.0 8.1 20.0 14.3 27.0 20.6 19.4 17.6 17.5 22.6 31.4 17.7 10.9 13.5 22.7 12.8 11.6 8.5 10.5 18.4 10.1 14.1 30.6 15.0 12.2 30.8 16.2 10.6 19.9 20.8 15.6 23.6 33.2 7.5 27.9 18.8 10.5 19.6 15.3 16.5 21.5 25.9 21.6 17.7 15.5 19.0 6.6 22.9 5.0 5.2 4.9 4.4 5.4 5.2 8.1 5.5 8.0 5.4 23.9 5.7 6.6 2.3 4.8 4.3 18.7 22.1 24.2 24.0 20.4 23.6 25.1 21.4 26.3 17.1 26.1 36.4 11.8 12.8 11.5 66.3 17.9 10.5 9.2 8.3 11.4 24.5 8.7 8.3 24.6 11.5 9.7 9.2 18.8 12.8 10.8 17.3 7.9 7.7 22.2 11.0 17.5 12.8 18.0 11.6 154.1 4.6 6.7 14.7 21.9 14.3 2.5 124.3 12.5 7.7 20.2 11.8 132.2 16.6 12.2 19.1 16.7 16.5 10.5 21.2 10.6 89.9 32.0 10.1 32.0 86.5 149.2 6.4 12.7 12.8 14.4 9.4 9.2 8.8 14.4 17.3 6.6 13.0 10.0 94.3 27.8 15.8 16.1 7.7 17.8 11.8 13.2 13.0 VPS9D1 "ATP-BL, C16orf7" ENSG00000075399 "VPS9 domain containing 1" Q9Y2B5 16 89707134-89720898 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.2;Inhibitory neurons: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "neutrophil: 18.0" "Lineage enriched" "Detected in single" 26 "granulocytes: 18.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007847, HPA023620" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Nucleoplasm "HPA007847: AB_1845582, HPA023620: AB_1845583" "unprognostic (7.08e-2)" "unprognostic (8.63e-2)" "unprognostic (6.26e-3)" "unprognostic (1.63e-3)" "unprognostic (5.67e-2)" "unprognostic (2.29e-3)" "unprognostic (5.03e-2)" "unprognostic (8.72e-2)" "unprognostic (2.39e-1)" "unprognostic (1.03e-1)" "unprognostic (8.23e-3)" "unprognostic (1.37e-1)" "prognostic favorable (2.91e-5)" "unprognostic (4.06e-2)" "unprognostic (3.55e-1)" "unprognostic (2.25e-1)" "unprognostic (3.13e-3)" 12.9 26.9 23.8 16.2 26.3 13.2 10.5 15.8 39.2 13.2 16.5 14.6 13.5 11.0 4.4 33.3 12.0 7.4 15.8 25.4 19.3 23.1 30.4 16.1 9.3 25.4 19.5 10.8 12.6 12.5 31.6 5.4 25.7 15.3 3.8 5.7 15.3 6.1 11.6 12.7 17.2 4.9 15.4 29.1 12.8 18.8 21.3 3.5 17.3 5.5 5.1 11.2 15.9 23.6 6.2 9.3 10.2 10.8 10.2 9.9 8.5 11.3 11.7 9.6 4.7 8.0 13.6 6.3 7.1 12.6 5.4 14.1 0.9 6.4 2.7 5.7 15.0 4.5 8.7 10.0 7.7 2.6 10.5 10.9 5.8 11.6 2.7 15.5 6.7 5.8 11.5 3.8 6.5 28.1 4.8 10.0 3.8 4.9 10.4 11.8 8.5 3.8 7.7 9.8 8.4 8.8 14.5 5.3 11.6 3.1 24.0 11.0 10.5 12.4 15.5 10.2 6.9 17.4 5.9 5.4 18.0 6.8 10.6 2.2 0.6 0.3 0.3 0.5 0.1 0.2 0.1 0.1 0.3 0.4 0.4 0.2 18.0 0.2 0.3 0.0 0.2 0.2 23.8 26.3 15.8 39.2 25.4 19.3 25.4 19.5 25.7 15.4 21.3 23.6 3.5 6.4 5.1 30.0 3.6 2.0 2.0 5.4 5.7 13.3 6.5 5.5 8.8 2.8 6.4 9.2 10.4 3.0 6.1 11.6 7.9 4.9 13.5 5.8 6.8 3.1 10.8 1.7 43.2 7.8 2.3 5.3 8.2 9.3 4.5 8.7 9.7 9.6 4.8 8.4 41.9 3.9 2.0 8.5 8.3 21.7 6.2 12.6 3.6 4.7 3.7 6.6 3.1 16.1 17.5 6.2 5.1 6.0 3.9 1.8 13.5 6.1 4.6 12.8 0.0 5.2 5.8 12.3 4.7 7.5 3.8 3.0 4.5 8.6 7.2 2.8 VSIG1 "GPA34, MGC44287" ENSG00000101842 "V-set and immunoglobulin domain containing 1" Q86XK7 X 108044970-108079184 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "stomach 1: 193.6" "Cell type enriched" "Detected in some" 10 "Gastric mucus-secreting cells: 333.8" "Group enriched" "Detected in many" 17 "lung cancer: 8.7;pancreatic cancer: 17.7;stomach cancer: 31.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 12.0;T-reg: 12.9" "Lineage enriched" "Detected in many" 4 "T-cells: 12.9" "Cell line enhanced" "Detected in some" "HBEC3-KT: 3.5;HUVEC TERT2: 7.4;PC-3: 2.3;TIME: 1.7" "Not detected" "Not detected" "HPA001445, HPA036310, HPA036311" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 4: Stomach - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Vesicles, Cytosol" "HPA001445: AB_10669749, HPA036310: AB_10670795, HPA036311: AB_10673350" "unprognostic (4.33e-3)" "unprognostic (4.60e-2)" "unprognostic (3.22e-2)" "unprognostic (1.60e-1)" "unprognostic (2.51e-1)" "unprognostic (4.80e-2)" "unprognostic (3.25e-2)" "unprognostic (9.79e-2)" "unprognostic (4.58e-1)" "unprognostic (2.35e-2)" "unprognostic (2.11e-2)" "unprognostic (1.25e-1)" "unprognostic (6.31e-7)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (2.19e-2)" "unprognostic (2.23e-3)" 0.0 0.1 0.1 1.3 0.3 0.5 0.1 0.2 0.3 0.0 0.2 0.2 1.2 0.1 0.3 0.2 0.0 8.4 0.0 0.2 0.2 0.1 0.1 1.0 1.9 0.1 0.1 0.0 0.2 0.0 2.6 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.4 0.5 0.0 0.0 0.8 193.6 47.7 0.1 0.8 0.1 0.0 1.6 8.9 0.1 0.1 0.1 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.0 1.1 0.0 7.4 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.2 0.6 2.3 0.2 0.0 0.0 0.3 0.6 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.1 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 1.0 0.0 3.8 2.8 8.1 3.6 0.0 1.3 12.0 5.8 0.3 0.1 0.1 0.1 12.9 2.6 0.1 0.3 0.2 0.3 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.2 25.6 11.0 1.0 2.4 0.6 0.9 0.7 0.0 0.9 0.2 0.1 0.5 1.5 0.7 0.0 0.0 0.0 0.1 0.4 0.0 2.9 6.1 1.1 0.1 1.0 0.0 0.0 4.1 4.6 0.0 0.6 333.8 0.2 2.5 0.0 0.0 0.0 0.1 0.0 1.4 0.3 0.0 0.0 0.4 10.8 0.6 0.7 0.0 0.0 0.3 0.1 1.0 0.0 0.1 32.9 0.0 0.0 1.0 0.6 0.0 0.0 0.9 0.8 0.0 1.1 0.2 1.0 0.6 0.0 0.0 0.1 4.5 0.2 0.1 3.8 VSIG10 ENSG00000176834 "V-set and immunoglobulin domain containing 10" Q8N0Z9 12 118063593-118136026 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 69.3;Proximal enterocytes: 106.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 33.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA062022 Enhanced Approved "Centriolar satellite,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Centriolar satellite" "HPA062022: AB_2732675" "unprognostic (1.32e-1)" "unprognostic (7.76e-2)" "unprognostic (2.05e-1)" "unprognostic (4.62e-3)" "unprognostic (1.09e-1)" "unprognostic (6.42e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.53e-4)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (2.49e-1)" "unprognostic (1.75e-1)" "unprognostic (2.85e-2)" "unprognostic (1.17e-1)" "unprognostic (1.80e-2)" "unprognostic (1.48e-2)" 6.1 11.3 4.5 2.3 5.5 0.8 6.0 5.4 4.6 6.8 4.8 13.3 13.9 4.3 3.1 8.7 4.7 3.8 3.8 3.9 4.5 6.2 5.7 8.4 1.5 6.0 4.9 6.4 7.1 8.1 4.4 8.6 4.9 5.9 15.8 1.9 7.0 5.2 17.0 5.6 24.5 3.2 5.4 3.9 6.5 2.6 5.3 0.9 12.1 10.8 2.1 5.9 6.9 4.8 7.9 11.4 4.8 16.1 19.4 8.8 12.4 13.3 8.5 6.4 5.3 3.3 18.2 1.1 5.3 9.8 12.0 18.9 33.8 3.4 7.6 4.0 5.1 1.8 11.0 5.0 3.9 1.1 2.7 4.0 9.8 4.9 3.1 18.6 14.2 3.8 2.3 0.1 6.1 8.3 0.0 1.1 14.9 22.8 7.5 2.8 13.2 0.0 9.4 25.1 4.1 5.3 13.0 5.4 3.4 10.2 11.9 5.3 16.8 7.4 4.7 9.2 6.8 0.1 0.1 0.1 10.7 5.5 15.0 0.2 0.5 0.6 0.1 0.1 0.1 0.0 0.1 0.0 0.6 0.1 0.1 0.1 1.0 0.1 0.0 0.1 0.1 0.1 4.5 5.5 5.4 4.6 3.9 4.5 6.0 4.9 4.9 5.4 5.3 4.8 23.6 19.2 28.6 14.0 3.3 2.4 13.0 1.8 6.8 9.9 15.1 11.7 11.4 31.5 5.0 29.5 12.5 38.0 2.2 69.3 19.6 26.2 6.1 10.3 13.0 19.1 50.4 9.9 4.7 20.3 41.0 11.9 16.8 13.6 2.5 33.3 21.0 27.5 11.2 5.0 5.1 40.4 2.0 6.7 9.4 9.9 18.0 5.6 3.6 3.7 7.4 18.9 2.1 9.0 3.1 26.7 45.3 14.7 3.1 10.4 106.6 13.7 2.7 7.9 0.0 12.9 8.6 4.0 6.1 12.4 3.1 14.0 4.0 24.7 48.2 15.3 VSTM1 UNQ3033 ENSG00000189068 "V-set and transmembrane domain containing 1" Q6UX27 19 54040825-54063953 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 43.2" "Cell type enhanced" "Detected in some" "Early spermatids: 3.4;Late spermatids: 20.3;Macrophages: 4.5;monocytes: 12.4;NK-cells: 3.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 16 "eosinophil: 129.2" "Lineage enriched" "Detected in many" 16 "granulocytes: 129.2" "Cell line enhanced" "Detected in some" "HMC-1: 1.0;hTERT-HME1: 1.0;U-2 OS: 1.0" "Low region specificity" "Detected in all" HPA059365 Approved Vesicles "Secreted to blood" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA059365: " "unprognostic (5.13e-2)" "unprognostic (5.31e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (3.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-1)" "unprognostic (9.47e-2)" "unprognostic (1.31e-5)" "unprognostic (3.73e-1)" "unprognostic (1.14e-1)" "unprognostic (9.74e-2)" "unprognostic (4.67e-2)" 0.2 0.1 0.0 0.2 0.0 43.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.1 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.0 0.0 1.4 0.0 4.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.0 3.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 7.4 129.2 0.0 6.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 8.1 0.0 0.0 4.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 3.4 0.2 0.1 0.1 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 2.1 0.0 0.4 0.0 0.0 2.5 0.0 20.3 0.0 4.5 0.0 0.0 12.4 0.0 3.1 0.5 0.6 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 VSTM2A "MGC33530, VSTM2" ENSG00000170419 "V-set and transmembrane domain containing 2A" Q8TAG5 7 54542325-54571080 "Plasma proteins, Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 10.2;brain: 31.3;prostate: 9.7;retina: 14.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 42.0;Enteroendocrine cells: 7.3;Excitatory neurons: 12.5;Fibroblasts: 10.9;Inhibitory neurons: 30.1" "Cancer enhanced" "Detected in some" "breast cancer: 4.6;glioma: 3.0" "Region enhanced" "Detected in many" "cerebral cortex: 31.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 4.2;SH-SY5Y: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 31000 "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.15e-1)" "unprognostic (1.02e-1)" "unprognostic (1.89e-1)" "unprognostic (1.14e-2)" "unprognostic (4.66e-1)" "prognostic favorable (5.34e-4)" "unprognostic (4.34e-2)" "unprognostic (6.79e-2)" "unprognostic (7.15e-2)" 0.0 10.2 4.4 0.0 9.9 0.0 0.3 0.0 31.3 0.0 0.0 4.4 1.4 0.0 0.0 0.0 0.0 0.1 0.0 10.5 6.6 0.0 0.0 0.0 0.0 2.2 1.5 0.0 0.6 0.0 0.3 0.0 0.0 9.7 4.0 14.3 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 4.7 0.4 13.7 0.0 0.2 0.2 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.2 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 9.9 0.0 31.3 10.5 6.6 2.2 1.5 0.0 0.7 13.7 2.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 42.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 7.3 0.0 12.5 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 2.5 0.5 0.0 1.1 0.0 0.0 0.2 0.0 0.1 0.7 4.1 0.0 0.2 2.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.4 0.3 VSTM2B ENSG00000187135 "V-set and transmembrane domain containing 2B" A6NLU5 19 29526499-29564479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 46.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 31.6;Excitatory neurons: 55.9;Inhibitory neurons: 37.8;Oligodendrocyte precursor cells: 97.5;Oligodendrocytes: 228.2" "Cancer enhanced" "Detected in some" "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SK-MEL-30: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.74e-1)" "unprognostic (1.87e-3)" "unprognostic (6.64e-2)" "unprognostic (1.08e-2)" "unprognostic (5.35e-2)" 0.0 0.1 32.2 0.0 41.0 0.0 0.0 14.7 46.8 2.9 0.2 0.4 0.0 0.1 0.4 0.0 0.1 0.0 0.0 35.6 23.1 0.0 0.0 0.0 0.0 26.4 20.6 0.0 0.0 0.0 0.2 0.0 24.1 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.2 17.2 0.0 0.0 0.0 27.5 0.0 0.0 0.0 0.0 0.0 1.7 40.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 32.2 41.0 14.7 46.8 35.6 23.1 26.4 20.6 24.1 17.2 27.5 40.9 0.0 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 55.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 37.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 2.1 0.0 97.5 228.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VSTM2L "C20orf102, dJ1118M15.2" ENSG00000132821 "V-set and transmembrane domain containing 2 like" Q96N03 20 37903111-37945350 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 87.0;heart muscle: 81.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 25.2;Cholangiocytes: 61.5;Club cells: 28.7;Inhibitory neurons: 44.0;Respiratory ciliated cells: 83.0" "Group enriched" "Detected in all" 5 "lung cancer: 23.6;pancreatic cancer: 34.4;prostate cancer: 72.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 67.2;HDLM-2: 98.8;hTCEpi: 23.4;SH-SY5Y: 22.5;SK-BR-3: 81.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043832 Uncertain "Secreted - unknown location" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA043832: AB_10968449" "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.33e-2)" "prognostic unfavorable (1.63e-5)" "unprognostic (4.96e-3)" "unprognostic (1.56e-1)" "unprognostic (1.83e-2)" "unprognostic (1.39e-1)" "unprognostic (1.52e-1)" "unprognostic (2.34e-3)" "unprognostic (9.86e-2)" "unprognostic (2.00e-1)" "unprognostic (1.85e-3)" "unprognostic (1.29e-3)" "unprognostic (1.68e-1)" "unprognostic (9.66e-2)" "prognostic unfavorable (8.14e-4)" 0.7 6.1 33.9 0.8 33.8 0.0 0.5 1.3 76.9 12.5 0.0 3.2 1.2 1.7 9.7 1.0 15.5 17.5 81.8 87.0 38.7 1.4 3.0 11.5 0.4 19.1 36.5 0.3 2.6 0.0 17.3 0.8 10.6 9.2 0.4 3.0 7.3 16.2 1.1 1.0 1.2 0.8 41.8 29.6 7.9 4.9 45.9 3.0 1.7 0.0 1.0 0.7 0.6 20.0 0.0 0.8 7.7 0.3 0.3 0.4 0.2 0.9 0.0 0.0 0.0 0.3 67.2 0.0 0.4 0.6 0.3 0.2 0.1 3.2 0.0 98.8 1.9 0.1 0.1 0.0 3.6 0.1 2.5 3.2 23.4 0.1 0.7 2.4 0.0 0.1 0.0 0.0 8.4 0.0 0.1 0.1 0.2 2.3 20.1 0.0 0.0 0.3 0.1 0.0 2.6 22.5 2.7 81.0 0.8 0.0 0.4 0.0 4.6 0.0 0.6 0.2 1.5 0.2 0.1 0.0 0.5 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.9 33.8 1.3 76.9 87.0 38.7 19.1 36.5 10.6 41.8 45.9 20.0 0.1 6.4 1.8 2.0 0.1 0.4 1.2 10.7 1.8 8.5 1.0 0.0 25.2 61.5 28.7 0.0 8.4 0.6 1.3 0.2 0.0 3.7 0.4 0.1 0.5 0.3 18.6 0.0 17.8 0.2 0.2 1.8 4.1 0.0 0.0 1.5 2.9 1.3 0.0 13.5 44.0 1.2 10.2 0.8 1.5 0.9 5.3 0.9 0.0 1.9 0.0 0.9 0.0 3.0 3.2 7.9 2.6 16.1 0.1 5.3 0.1 1.0 83.0 4.6 0.0 0.0 2.9 0.2 0.8 0.1 0.6 0.1 1.2 3.5 0.2 0.7 VSTM4 "C10orf72, FLJ31737" ENSG00000165633 "V-set and transmembrane domain containing 4" Q8IW00 10 49014236-49115522 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Granulosa cells: 96.9;Late spermatids: 140.6;Sertoli cells: 59.2;Theca cells: 44.7" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 22.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 8.6;RH-30: 9.3;SH-SY5Y: 7.9;U-138 MG: 10.6;U-2197: 24.0;U-87 MG: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017279 Uncertain Approved Nucleoplasm,Vesicles "Secreted - unknown location" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "HPA017279: AB_10959519" "unprognostic (8.46e-2)" "unprognostic (5.41e-1)" "unprognostic (1.89e-1)" "unprognostic (2.07e-1)" "unprognostic (1.80e-1)" "unprognostic (2.84e-2)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.62e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.25e-4)" 18.7 41.5 7.1 3.2 9.0 0.3 9.8 8.0 6.6 22.3 7.7 7.8 2.5 12.3 7.4 7.8 8.5 10.5 12.3 6.2 7.6 12.3 3.9 10.9 3.5 8.9 9.3 35.2 1.5 26.8 5.1 10.4 9.2 13.5 5.6 2.3 3.4 11.7 5.6 4.9 4.9 11.4 8.6 2.3 5.6 9.4 8.4 6.5 27.8 5.9 4.6 12.0 7.5 9.4 0.0 0.0 3.1 0.1 1.3 0.7 0.1 2.6 4.1 0.9 0.2 0.0 0.1 0.1 0.1 6.1 3.4 0.1 0.2 0.0 0.4 3.2 1.4 0.2 0.1 0.1 0.1 0.1 0.0 4.7 0.0 4.2 0.0 0.0 0.0 0.8 8.6 0.1 0.8 0.1 0.0 0.2 0.6 0.0 0.0 0.0 9.3 5.0 0.0 0.1 0.1 7.9 0.1 0.0 0.0 0.4 0.1 0.3 0.0 10.6 1.2 24.0 0.1 0.0 6.8 0.0 11.6 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.5 0.3 0.1 0.1 0.0 0.0 7.1 9.0 8.0 6.6 6.2 7.6 8.9 9.3 9.2 8.6 8.4 9.4 9.4 3.2 17.5 17.3 1.3 6.5 1.6 0.1 0.6 5.4 1.2 1.1 16.7 0.0 9.4 0.0 2.1 0.4 3.7 0.2 1.9 0.1 88.5 0.8 10.7 6.2 0.0 0.0 11.1 0.0 0.3 29.7 0.0 0.7 12.6 96.9 5.3 5.0 0.7 5.0 7.0 0.0 0.0 2.2 11.1 140.6 9.6 2.9 7.2 4.7 1.0 9.1 2.1 20.1 33.3 0.2 0.1 14.7 0.7 0.8 0.0 9.4 3.8 2.9 59.2 20.6 37.7 1.3 4.4 0.4 4.3 0.4 2.0 44.7 0.0 0.7 VTN VN ENSG00000109072 Vitronectin P04004 17 28367284-28373091 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 6039.5" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 5507.4" "Cancer enriched" "Detected in many" 85 "liver cancer: 2216.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "CACO-2: 1748.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016695, CAB016765, HPA060933, HPA068011" Supported Supported "Endoplasmic reticulum,Vesicles" "Secreted to blood" NA NA 606000000000 33000000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Vesicles" "CAB016695: AB_1624536, CAB016765: , HPA060933: AB_2684389, HPA068011: " "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (2.29e-2)" "unprognostic (6.13e-2)" "unprognostic (9.74e-2)" "unprognostic (8.42e-2)" "prognostic favorable (3.74e-4)" "unprognostic (6.20e-2)" "unprognostic (3.97e-1)" "unprognostic (8.95e-2)" "unprognostic (3.24e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.10e-11)" "unprognostic (8.82e-3)" "unprognostic (2.27e-1)" "unprognostic (4.86e-3)" "unprognostic (7.09e-2)" 6.2 98.9 2.4 2.5 2.7 0.3 0.9 5.4 3.7 1.0 0.4 0.9 4.6 1.4 0.9 0.5 2.2 61.2 53.1 2.5 2.8 3.6 6039.5 1.8 4.3 2.1 5.3 1.9 17.7 0.1 3.0 40.6 2.3 1.2 0.3 47.4 0.6 4.3 0.4 0.8 1.3 2.7 1.5 2.9 5.1 10.0 2.2 0.1 0.8 0.5 0.4 4.2 0.7 2.4 0.0 28.4 0.7 0.4 0.2 0.3 7.3 1.8 0.8 0.9 0.9 1748.9 0.1 1.2 0.2 0.2 0.2 0.7 0.0 0.0 0.1 0.2 0.2 1.2 1.1 86.7 2.5 6.1 0.5 0.4 0.0 0.6 0.0 3.9 0.1 0.0 1.6 0.3 0.2 0.7 0.2 0.0 0.8 0.4 0.1 0.4 3.5 0.1 0.3 0.0 1.0 1.4 115.6 8.0 0.2 4.3 0.3 0.0 1.0 0.4 0.3 0.1 0.2 1.0 0.5 1.4 0.5 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 2.4 2.7 5.4 3.7 2.5 2.8 2.1 5.3 2.3 1.5 2.2 2.4 0.1 0.0 1.1 2.0 21.5 0.0 0.0 0.0 0.0 13.0 0.1 0.1 18.1 1162.4 0.0 0.0 77.2 3.7 0.0 0.0 3.9 16.8 0.0 0.0 1.2 7.3 0.0 131.0 0.9 19.7 2.8 48.1 0.0 0.0 0.0 1.8 120.3 5507.4 4.7 38.7 1.0 0.1 0.0 160.3 0.3 0.2 0.0 0.3 0.0 0.0 20.1 6.9 0.0 1.0 0.5 23.5 1.2 1.5 0.0 0.0 0.1 9.5 0.0 38.3 0.0 0.4 1.5 4.2 0.6 0.0 0.0 9.6 9.0 0.7 0.0 0.0 VWA1 "FLJ22215, VWA-1, WARP" ENSG00000179403 "Von Willebrand factor A domain containing 1" Q6PCB0 1 1434861-1442882 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 275.1;Endothelial cells: 142.7;Syncytiotrophoblasts: 290.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 47.2;CACO-2: 46.7;CAPAN-2: 136.6;Hep G2: 84.4;SCLC-21H: 47.6;T-47d: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 250000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (2.78e-1)" "unprognostic (4.85e-2)" "unprognostic (5.91e-3)" "unprognostic (2.75e-1)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (9.52e-3)" "unprognostic (8.11e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (3.47e-1)" "unprognostic (2.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-2)" "unprognostic (3.08e-2)" "unprognostic (6.71e-2)" 36.2 15.2 55.3 31.5 91.7 0.2 38.4 79.4 76.7 51.0 24.4 114.3 15.3 70.4 11.5 41.3 50.4 22.4 38.0 59.4 58.9 58.6 133.3 29.6 13.7 103.4 81.6 22.5 55.3 12.5 20.0 38.4 87.9 131.3 5.3 2.3 64.0 203.6 10.1 26.2 37.6 20.4 74.2 11.7 52.6 27.1 88.3 3.0 67.4 3.4 5.1 118.5 50.6 151.2 47.2 15.4 2.2 15.7 0.4 1.4 24.5 3.1 0.1 2.2 0.1 46.7 136.6 0.0 43.0 1.3 5.0 12.1 15.9 8.1 0.3 3.0 11.3 1.5 0.1 84.4 3.5 0.0 5.5 2.7 0.4 1.0 0.0 0.4 0.6 0.0 1.6 0.0 0.1 11.7 0.1 0.9 6.1 16.5 4.3 0.6 0.8 2.2 2.7 7.9 47.6 7.4 0.0 41.7 5.8 3.7 61.1 0.6 1.4 0.1 0.6 0.4 15.2 0.3 0.2 0.2 2.3 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 91.7 79.4 76.7 59.4 58.9 103.4 81.6 87.9 74.2 88.3 151.2 103.4 19.2 36.1 5.9 2.8 6.5 19.1 5.2 12.0 7.6 40.4 59.4 3.6 44.3 14.2 53.3 4.2 275.1 1.4 24.2 7.9 82.0 0.6 16.0 46.2 142.7 12.5 2.7 0.5 65.0 99.2 28.3 16.8 17.7 1.3 2.0 8.2 49.4 22.8 15.2 1.5 8.9 6.1 1.0 4.3 4.0 34.2 1.1 24.9 18.7 2.6 52.1 0.0 13.0 48.7 48.0 11.0 59.0 2.6 21.5 0.8 5.4 10.7 4.3 6.6 62.4 17.2 0.8 2.1 11.9 8.5 290.3 1.3 6.3 10.4 14.9 VWA2 "AMACO, CCSP-2, FLJ16213, FLJ45857, NET42" ENSG00000165816 "Von Willebrand factor A domain containing 2" Q5GFL6 10 114239254-114294489 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 8.4" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 6.8;Early spermatids: 9.6;Gastric mucus-secreting cells: 5.1;Late spermatids: 15.8;Microglial cells: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 5.7;HaCaT: 3.0;SCLC-21H: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037847 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA037847: AB_10670961" "unprognostic (6.03e-2)" "unprognostic (8.29e-2)" "unprognostic (3.27e-2)" "unprognostic (7.33e-2)" "unprognostic (1.26e-2)" "unprognostic (6.82e-2)" "unprognostic (3.02e-2)" "unprognostic (9.33e-3)" "unprognostic (2.44e-1)" "unprognostic (3.70e-1)" "unprognostic (1.37e-3)" "unprognostic (3.14e-1)" "unprognostic (7.27e-3)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (9.30e-2)" "unprognostic (1.22e-1)" 0.5 0.0 2.7 0.4 1.6 0.5 3.1 2.2 1.6 4.0 0.3 1.3 1.6 0.9 1.0 1.2 6.4 0.2 0.0 1.4 1.3 0.5 0.0 3.3 0.2 1.9 1.7 0.1 2.3 0.2 0.3 0.4 1.8 5.4 1.0 0.3 4.5 1.0 0.3 6.4 1.4 0.1 1.7 1.4 8.4 1.1 2.1 3.4 0.8 0.2 0.5 0.7 0.9 1.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.3 0.0 0.0 3.0 0.0 0.6 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 1.6 0.0 0.0 0.6 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.7 1.6 2.2 1.6 1.4 1.3 1.9 1.7 1.8 1.7 2.1 1.5 0.4 0.0 0.0 0.0 0.0 0.3 4.1 2.8 6.8 0.0 1.1 0.3 0.5 0.0 1.7 1.8 0.0 1.3 0.0 0.1 0.0 2.1 9.6 0.7 0.1 0.2 0.0 0.0 4.1 1.6 0.0 0.1 5.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 1.0 0.4 2.0 0.0 0.0 15.8 0.3 0.0 0.0 16.9 0.0 0.0 0.0 2.5 0.1 2.2 0.2 0.0 0.0 2.0 0.6 0.1 0.6 0.0 0.0 0.2 0.1 0.8 0.3 1.1 0.0 0.7 0.0 0.1 0.5 1.3 VWA5B2 "DKFZp761K032, LOC90113" ENSG00000145198 "Von Willebrand factor A domain containing 5B2" Q8N398 3 184230429-184242329 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 40.7;brain: 16.4" "Group enriched" "Detected in some" 7 "Enteroendocrine cells: 112.4;Excitatory neurons: 39.2;Inhibitory neurons: 29.2" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.9;pancreatic cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "SCLC-21H: 31.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 22.9" "HPA036823, HPA036824, HPA061412" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" Nucleoplasm "HPA036823: AB_10672269, HPA036824: AB_2675334, HPA061412: AB_2684507" "unprognostic (3.92e-4)" "unprognostic (1.70e-1)" "unprognostic (1.69e-2)" "unprognostic (2.56e-3)" "unprognostic (3.37e-1)" "unprognostic (1.60e-1)" "unprognostic (1.70e-2)" "unprognostic (1.21e-1)" "unprognostic (3.80e-1)" "unprognostic (1.21e-1)" "unprognostic (4.32e-3)" "unprognostic (3.73e-2)" "unprognostic (1.12e-4)" "unprognostic (3.13e-1)" "unprognostic (3.65e-2)" "unprognostic (2.36e-1)" "unprognostic (1.83e-1)" 0.0 40.7 7.8 0.0 1.7 0.1 0.0 0.7 16.4 0.5 0.0 0.4 1.8 0.2 0.1 0.0 1.3 0.0 0.0 6.5 0.7 0.2 0.0 0.1 0.0 7.4 0.5 0.4 5.6 1.4 8.3 0.0 5.0 0.5 0.3 0.2 0.6 2.4 0.0 0.0 1.1 0.0 0.0 0.0 2.8 1.0 2.6 0.0 0.3 0.0 0.0 0.1 0.1 2.0 0.0 0.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 1.9 0.3 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.7 0.4 0.3 0.0 0.0 31.7 2.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 3.1 0.1 0.0 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 1.7 0.7 16.4 6.5 0.7 7.4 0.5 5.0 0.0 2.6 2.0 0.4 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 7.6 0.1 0.1 112.4 0.0 39.2 0.2 0.0 0.0 6.1 0.8 0.0 0.2 1.1 0.0 0.2 3.3 29.2 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.0 1.7 0.2 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.6 0.1 VWA7 "C6orf27, G7c, NG37" ENSG00000204396 "Von Willebrand factor A domain containing 7" Q9Y334 6 31765590-31777328 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 21.3" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 4.2;Gastric mucus-secreting cells: 8.2;Proximal enterocytes: 5.0;Proximal tubular cells: 2.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebral cortex: 2.9;hypothalamus: 8.2;medulla oblongata: 5.9;pons: 5.5;thalamus: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.2;HMC-1: 1.3;Karpas-707: 1.1;U-266/84: 1.6" "Group enriched" "Detected in some" 5 "cerebellum: 7.0;pons and medulla: 3.9" "Low region specificity" "Detected in many" "HPA046954, HPA054262" Approved Approved "Plasma membrane,Cytosol" "Secreted - unknown location" NA NA 9200 "Cluster 10: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA046954: AB_2679875, HPA054262: AB_2682430" "unprognostic (9.13e-2)" "unprognostic (8.60e-4)" "unprognostic (9.99e-2)" "unprognostic (2.43e-1)" "unprognostic (2.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.38e-2)" "unprognostic (4.40e-2)" "unprognostic (2.68e-1)" "unprognostic (5.84e-2)" "unprognostic (1.65e-2)" "unprognostic (9.25e-2)" "prognostic favorable (4.35e-8)" "unprognostic (3.75e-2)" "unprognostic (2.37e-1)" "unprognostic (9.48e-2)" "unprognostic (7.66e-2)" 0.4 0.3 0.5 0.1 0.3 0.0 0.7 0.1 2.9 0.8 0.0 1.3 1.0 4.6 0.0 0.4 7.2 0.7 5.2 0.8 8.2 5.7 1.4 1.4 0.1 5.9 1.0 0.5 2.6 1.7 21.3 0.0 5.5 0.8 0.4 0.2 1.4 1.3 6.6 0.8 2.3 0.0 0.0 0.5 3.0 0.7 7.5 0.0 1.8 0.0 0.1 0.6 0.7 1.0 0.8 1.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.7 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.7 0.0 0.0 0.1 0.0 0.9 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.6 0.1 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 1.6 0.0 0.0 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.1 2.9 0.8 8.2 5.9 1.0 5.5 0.0 7.5 1.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 0.5 1.2 0.5 0.1 0.3 0.8 0.0 0.3 1.8 0.0 0.0 0.2 1.4 1.9 0.6 0.0 1.5 0.1 0.1 4.2 0.0 1.5 0.5 0.0 0.1 8.2 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.6 2.1 0.0 0.4 0.3 5.0 2.4 1.6 0.8 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.3 0.4 0.0 0.5 0.4 VWC2 "PSST739, UNQ739" ENSG00000188730 "Von Willebrand factor C domain containing 2" Q2TAL6 7 49773638-49921950 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.9;heart muscle: 5.0;ovary: 4.9" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 361.7;Oligodendrocyte precursor cells: 163.3" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 8.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA055243 Approved "Secreted to extracellular matrix" NA NA 39000 "Cluster 21: Non-specific - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA055243: AB_2682755" "unprognostic (3.30e-1)" "unprognostic (1.04e-1)" "unprognostic (8.90e-4)" "unprognostic (8.97e-2)" "unprognostic (8.77e-2)" "unprognostic (1.56e-3)" "unprognostic (3.41e-2)" "unprognostic (4.11e-1)" "unprognostic (6.65e-2)" "unprognostic (1.69e-4)" "unprognostic (1.60e-2)" "unprognostic (2.09e-2)" "unprognostic (1.52e-1)" "unprognostic (1.94e-1)" "unprognostic (9.70e-3)" 0.1 0.0 2.5 0.0 2.6 0.0 0.0 8.9 1.7 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 5.0 0.6 1.6 0.1 0.0 0.1 0.0 0.8 1.9 4.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.1 0.4 0.3 0.1 0.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.6 8.9 1.7 0.6 1.6 0.8 1.9 0.9 0.3 4.0 0.5 0.0 0.0 0.0 3.3 0.0 0.5 0.1 0.0 10.8 22.6 0.0 0.0 50.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 18.4 0.5 0.0 0.0 65.2 0.0 0.0 1.6 0.0 0.4 0.0 47.6 0.0 0.0 0.0 1.7 361.7 0.2 0.0 0.0 1.6 0.0 0.0 0.3 0.0 10.3 0.0 0.9 0.0 163.3 1.7 0.0 7.3 0.0 0.1 0.2 0.1 0.0 0.0 13.5 0.0 0.1 2.7 0.0 0.4 0.7 2.0 0.0 0.3 0.6 0.3 0.2 VWC2L ENSG00000174453 "Von Willebrand factor C domain containing 2 like" B2RUY7 2 214411054-214578976 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 2.7;retina: 1.4" "Group enriched" "Detected in some" 21 "Excitatory neurons: 67.4;Inhibitory neurons: 132.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044815, HPA059414" Uncertain "Secreted - unknown location" NA NA "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044815: AB_10962359, HPA059414: AB_2684007" "unprognostic (8.77e-2)" "unprognostic (2.83e-3)" "unprognostic (2.05e-2)" "unprognostic (8.49e-2)" "unprognostic (1.51e-3)" "unprognostic (4.36e-1)" "unprognostic (2.56e-2)" "unprognostic (2.05e-1)" "unprognostic (3.89e-1)" 0.0 0.0 2.1 0.0 1.7 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.2 0.0 0.0 0.0 0.0 0.8 1.8 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.7 0.1 2.1 2.7 2.2 0.8 1.8 1.8 0.2 2.3 1.8 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 67.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 132.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.1 0.0 4.5 2.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 VWCE "FLJ32009, URG11, VWC1" ENSG00000167992 "Von Willebrand factor C and EGF domains" Q96DN2 11 61258286-61295316 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 14.3;ovary: 7.9" "Cell type enhanced" "Detected in many" "Astrocytes: 19.2;Cone photoreceptor cells: 29.2;Hepatocytes: 16.4;Rod photoreceptor cells: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 7.2;Hep G2: 26.3;HSkMC: 13.4;REH: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA040401, HPA043921" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2200000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Vesicles, Cytosol" "HPA040401: AB_2676963, HPA043921: AB_2678731" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (3.58e-2)" "unprognostic (1.15e-1)" "unprognostic (3.96e-3)" "unprognostic (9.27e-4)" "unprognostic (1.21e-2)" "unprognostic (4.01e-4)" "unprognostic (3.04e-2)" "unprognostic (3.42e-2)" "unprognostic (6.58e-4)" "unprognostic (7.20e-2)" "unprognostic (3.01e-1)" "unprognostic (1.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-1)" 2.8 1.1 0.6 0.1 0.9 1.6 1.5 0.3 1.6 2.9 0.0 0.6 0.3 1.3 0.6 0.9 3.5 0.6 0.8 0.7 0.7 0.5 14.3 0.3 0.2 0.5 1.2 7.9 0.3 0.1 0.6 2.4 0.4 1.0 0.4 0.8 0.9 0.5 0.7 0.7 0.4 0.4 0.0 0.4 0.4 1.8 0.5 2.5 0.8 0.4 0.1 0.6 1.2 0.2 0.0 0.1 1.5 0.2 0.2 1.8 0.6 0.2 2.0 0.0 0.3 7.2 0.0 0.5 0.0 0.4 0.1 0.0 2.3 0.0 0.1 0.4 0.0 0.8 0.0 26.3 1.2 0.0 0.3 13.4 0.6 0.7 0.0 0.1 2.3 3.3 0.2 0.3 0.3 0.1 5.5 0.0 2.2 0.0 0.0 14.0 0.2 0.0 0.1 0.1 0.6 1.0 0.0 0.1 0.7 2.4 0.9 0.0 0.8 0.3 0.3 0.5 0.2 0.2 0.6 1.2 0.9 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.3 1.6 0.7 0.7 0.5 1.2 0.4 0.0 0.5 0.2 2.1 3.2 1.7 19.2 0.3 1.8 1.8 3.8 3.4 3.6 1.7 0.5 1.0 1.5 2.3 0.0 29.2 1.0 0.5 0.2 0.0 0.1 0.5 2.9 1.0 5.5 1.8 6.1 7.5 0.5 5.0 2.6 0.0 1.8 3.8 6.5 2.5 16.4 1.2 0.0 5.8 0.1 2.0 3.5 2.4 0.8 6.8 2.6 1.8 2.8 2.3 2.3 1.0 2.5 1.4 0.0 0.0 1.9 0.4 1.1 0.1 0.3 5.4 21.1 0.0 0.9 1.1 1.1 3.4 1.3 2.3 4.4 0.9 7.7 0.3 0.7 VWDE FLJ14712 ENSG00000146530 "Von Willebrand factor D and EGF domains" Q8N2E2 7 12330885-12403941 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 4.3;salivary gland: 3.3;thyroid gland: 3.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.8;Excitatory neurons: 11.8;Granulosa cells: 5.4;Inhibitory neurons: 11.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 5.0;K-562: 13.0;NTERA-2: 4.8;SCLC-21H: 7.0" "Low region specificity" "Detected in many" "HPA026619, HPA036044, HPA036045" Uncertain Approved Cytosol "Secreted - unknown location" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA026619: AB_2671920, HPA036044: AB_2674916, HPA036045: " "unprognostic (6.39e-2)" "unprognostic (1.65e-3)" "unprognostic (5.36e-3)" "unprognostic (1.78e-4)" "unprognostic (1.39e-2)" "unprognostic (4.19e-3)" "unprognostic (2.38e-1)" "unprognostic (1.85e-1)" "unprognostic (1.78e-1)" "unprognostic (6.25e-2)" "unprognostic (1.68e-1)" "unprognostic (6.72e-2)" "unprognostic (1.84e-1)" "unprognostic (2.11e-3)" "unprognostic (1.58e-1)" "unprognostic (1.10e-1)" "unprognostic (2.73e-1)" 0.0 0.3 0.5 0.1 0.8 2.3 1.6 0.0 0.5 0.1 0.0 0.3 0.1 0.4 4.3 0.1 1.1 0.4 2.0 0.4 0.3 0.2 0.1 0.2 0.1 0.4 0.4 0.0 0.0 0.3 0.4 0.1 0.3 1.1 0.1 0.0 3.3 1.6 0.0 0.4 0.1 0.1 0.5 0.1 0.7 0.2 0.3 0.1 3.1 0.0 0.0 0.4 0.0 0.1 0.0 0.8 0.0 1.2 0.0 0.2 2.4 0.0 1.5 0.5 0.7 0.3 2.4 0.1 0.0 0.0 0.9 0.7 1.7 1.6 1.1 2.7 2.4 3.4 5.0 0.0 0.0 1.9 1.5 0.1 0.2 0.0 1.1 2.4 1.0 1.3 13.0 0.0 0.0 1.6 0.0 0.0 4.8 0.0 0.8 0.0 0.0 1.1 0.4 1.2 7.0 1.5 0.0 1.4 0.0 1.7 0.0 0.8 0.1 0.0 0.9 0.0 1.5 2.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.8 0.0 0.5 0.4 0.3 0.4 0.4 0.3 0.5 0.3 0.1 0.1 0.0 1.5 0.3 0.0 0.3 2.1 0.9 2.8 0.0 1.6 1.0 8.8 0.0 1.2 0.0 0.0 0.3 0.0 0.2 0.0 0.1 1.2 0.7 0.2 0.2 0.0 3.0 11.8 0.0 0.5 1.1 0.0 1.8 0.0 5.4 0.0 0.0 0.1 0.0 11.6 0.1 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 1.2 0.0 0.0 2.9 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.4 0.4 0.7 0.1 0.1 0.7 0.4 0.5 1.8 VWF F8VWF ENSG00000110799 "Von Willebrand factor" P04275 12 5948877-6124770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 904.3;Endothelial cells: 737.5;Hepatic stellate cells: 424.4" "Cancer enhanced" "Detected in all" "renal cancer: 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "HUVEC TERT2: 560.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001694, HPA001815, HPA002082, CAB072874, CAB072875" Supported "Secreted to blood" NA NA 28300000000 5600000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB001694: , CAB072874: AB_2665726, CAB072875: AB_2665727, HPA001815: AB_611880, HPA002082: AB_1080575" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-3)" "unprognostic (7.09e-2)" "unprognostic (4.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.92e-2)" "unprognostic (4.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.55e-1)" "unprognostic (3.12e-1)" "unprognostic (2.73e-3)" 151.9 5.9 40.0 20.2 38.8 0.8 117.3 32.9 31.4 46.0 29.2 32.7 12.8 51.1 10.6 21.9 45.7 30.2 137.8 27.4 32.3 9.7 2.1 106.2 22.8 37.6 37.4 22.0 15.0 27.3 6.3 72.7 41.7 27.4 9.2 2.9 18.1 19.2 57.0 23.5 34.5 44.2 32.2 44.1 25.7 10.8 52.4 7.0 50.8 51.6 9.5 39.7 35.5 37.1 0.0 0.0 0.0 0.0 0.7 0.6 0.5 0.0 0.6 0.2 0.4 0.0 0.3 0.0 1.2 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 560.9 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.3 0.5 0.4 0.0 0.1 10.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 40.0 38.8 32.9 31.4 27.4 32.3 37.6 37.4 41.7 32.2 52.4 37.1 904.3 12.8 25.7 3.6 1.0 6.6 0.6 1.3 4.6 0.0 4.5 4.7 112.2 1.5 1.7 11.0 0.0 1.1 2.6 0.0 0.0 0.5 6.8 2.0 1.6 737.5 0.0 2.7 2.9 0.0 0.9 21.1 0.0 2.1 5.7 0.1 424.4 3.3 0.5 0.0 2.2 0.0 4.1 5.3 3.4 15.5 5.9 2.6 5.4 75.9 0.3 0.7 0.0 1.5 4.2 0.0 0.0 0.7 0.0 1.3 0.0 0.1 1.0 1.7 0.0 12.4 34.7 2.9 5.7 4.7 4.3 1.0 2.0 10.6 0.0 1.7 WDR17 ENSG00000150627 "WD repeat domain 17" Q8IZU2 4 176065841-176182818 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 11.5;retina: 28.6" "Cell type enhanced" "Detected in many" "Astrocytes: 183.1;Cone photoreceptor cells: 64.6;Excitatory neurons: 222.8;Inhibitory neurons: 127.6;Oligodendrocyte precursor cells: 125.2" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 5.6;SCLC-21H: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042766, HPA054501" Approved Approved "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "HPA042766: AB_10806372, HPA054501: AB_2732586" "unprognostic (3.41e-4)" "unprognostic (1.72e-1)" "unprognostic (1.20e-1)" "unprognostic (6.43e-7)" "unprognostic (3.53e-1)" "unprognostic (1.40e-1)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (8.62e-2)" "unprognostic (1.42e-1)" "unprognostic (1.39e-3)" "unprognostic (6.04e-4)" "unprognostic (3.66e-4)" "unprognostic (9.25e-3)" "unprognostic (4.63e-2)" "unprognostic (7.32e-3)" "unprognostic (8.24e-3)" 0.8 2.9 4.5 0.9 7.9 0.6 1.3 2.9 7.6 1.4 0.0 2.5 0.5 1.8 2.4 0.6 1.9 1.1 0.8 8.5 2.5 2.5 0.3 1.4 0.6 0.0 0.0 1.8 2.2 7.0 11.5 0.1 0.8 0.8 1.1 28.6 0.8 0.8 0.2 0.4 1.2 1.0 0.0 1.1 1.3 1.9 2.3 0.3 4.3 0.3 0.5 1.4 1.0 3.4 0.0 2.5 5.6 0.0 0.1 0.4 0.2 0.1 0.0 0.6 1.9 0.2 0.0 3.7 0.0 0.1 3.0 0.0 2.4 1.4 0.5 0.0 2.0 0.0 0.5 0.0 0.2 2.0 2.8 0.8 0.7 0.1 0.3 0.7 0.0 4.3 0.0 0.3 0.5 1.1 2.4 0.1 1.2 0.0 1.4 0.0 2.5 0.0 0.2 0.0 7.6 4.8 0.0 1.4 3.8 0.7 0.4 0.0 0.0 0.8 1.0 0.0 3.4 2.7 1.8 2.3 4.2 0.0 1.4 0.4 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.1 0.0 0.0 4.5 7.9 2.9 7.6 8.5 2.5 0.0 0.0 0.8 0.0 2.3 3.4 0.3 0.0 5.8 183.1 2.4 0.1 0.5 0.1 3.4 16.9 0.6 0.9 0.9 1.5 1.3 0.0 64.6 0.0 0.0 0.1 1.9 0.3 1.5 0.5 0.6 0.7 4.8 1.7 222.8 0.6 0.0 2.0 0.0 0.0 3.8 0.1 2.2 0.1 0.2 21.9 127.6 0.1 0.0 0.6 0.6 1.5 0.9 1.3 1.8 23.4 0.6 10.2 0.0 125.2 40.0 0.2 0.0 1.5 0.2 0.4 0.0 11.6 7.7 36.6 0.0 3.0 1.9 2.7 5.2 0.4 0.0 0.0 0.3 1.4 0.1 0.3 WDR25 "C14orf67, MGC4645" ENSG00000176473 "WD repeat domain 25" Q64LD2 14 100376418-100530303 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 33.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003113 Uncertain Approved Nucleoplasm "Secreted to blood" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "HPA003113: AB_2215263" "unprognostic (5.31e-2)" "unprognostic (5.76e-3)" "unprognostic (2.28e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.36e-4)" "unprognostic (1.79e-2)" "unprognostic (6.62e-2)" "unprognostic (3.94e-3)" "unprognostic (2.44e-2)" "unprognostic (1.37e-2)" "prognostic favorable (3.89e-5)" "unprognostic (1.01e-2)" "unprognostic (1.73e-1)" "unprognostic (7.30e-2)" "unprognostic (7.51e-2)" 6.4 10.0 7.6 2.5 7.8 4.1 6.5 8.0 9.5 8.1 8.1 6.7 3.2 7.9 4.2 4.5 6.8 3.0 6.6 7.4 7.5 7.0 8.6 5.8 3.6 7.6 7.6 6.6 12.9 3.5 11.3 3.3 8.5 7.9 2.5 4.5 5.7 3.6 10.7 5.7 4.8 2.7 7.0 5.7 6.5 7.4 7.3 5.6 9.1 4.5 2.3 7.9 5.4 7.8 3.5 6.1 4.2 15.6 6.7 6.2 3.5 6.4 10.2 7.3 7.4 2.9 6.5 5.1 7.9 5.0 2.0 6.2 4.0 7.8 3.8 5.0 2.9 3.4 6.9 4.9 12.2 4.0 3.8 9.3 9.2 5.3 7.9 6.4 5.3 5.9 4.2 7.3 4.8 13.5 6.0 4.4 3.2 4.2 10.7 4.3 5.9 3.6 5.6 2.8 9.8 10.3 5.2 1.9 9.0 4.0 7.2 1.4 9.2 2.8 3.2 10.8 3.7 4.9 2.6 2.5 9.7 3.0 5.4 34.0 16.4 24.6 8.6 14.6 8.7 13.0 11.1 9.1 14.3 8.5 11.7 8.6 8.7 5.6 16.3 11.0 12.0 12.2 7.6 7.8 8.0 9.5 7.4 7.5 7.6 7.6 8.5 7.0 7.3 7.8 7.1 0.0 6.4 12.1 5.1 3.2 4.3 8.6 0.6 8.8 5.5 6.1 2.6 0.0 6.9 3.7 10.4 8.4 6.7 6.3 9.8 12.7 9.2 13.8 6.7 8.8 5.4 11.0 17.8 33.6 4.7 6.2 8.2 8.5 3.8 3.9 5.0 8.7 6.9 5.0 16.9 9.0 14.2 5.6 4.0 6.3 6.8 3.7 5.4 16.9 5.4 14.0 5.2 14.6 19.1 13.3 3.8 11.3 6.3 3.3 7.5 17.9 11.8 16.2 13.1 4.5 7.2 15.6 17.0 2.8 3.0 7.0 5.0 9.2 7.1 3.0 WDR26 "FLJ21016, GID7" ENSG00000162923 "WD repeat domain 26" Q9H7D7 1 224385146-224437033 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 243.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028538, HPA028539, HPA061094" Enhanced Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" Mitochondria "HPA028538: , HPA028539: AB_10669752, HPA061094: AB_2684427" "unprognostic (4.09e-3)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.31e-2)" "unprognostic (6.67e-2)" "unprognostic (2.27e-1)" "unprognostic (1.24e-1)" "unprognostic (1.64e-1)" "unprognostic (8.42e-2)" "unprognostic (6.32e-2)" "unprognostic (5.59e-2)" "unprognostic (4.18e-1)" "prognostic unfavorable (3.31e-6)" "unprognostic (8.40e-3)" "unprognostic (4.00e-1)" "unprognostic (2.17e-1)" "unprognostic (2.28e-1)" 33.7 28.3 21.9 32.1 21.3 88.9 26.7 20.0 22.0 28.9 27.5 28.9 21.2 26.5 20.8 52.1 22.7 27.1 28.0 23.4 22.8 23.7 35.4 35.1 33.8 21.5 22.0 24.3 24.4 26.4 20.6 35.6 20.2 26.1 25.4 31.5 28.7 25.0 57.1 40.9 26.5 28.6 18.8 38.2 26.7 37.4 22.1 36.0 26.0 45.0 33.2 32.6 31.5 21.9 49.7 28.0 54.6 29.7 76.8 74.6 47.6 58.4 86.4 51.7 48.0 39.0 46.8 51.9 74.4 86.3 21.7 40.6 40.2 47.2 76.1 55.3 53.6 36.2 31.5 31.0 74.7 40.3 68.6 70.8 58.4 55.0 52.1 72.6 80.8 31.7 52.7 51.4 62.4 24.8 42.4 34.7 65.7 41.5 32.0 42.6 66.1 44.2 55.1 48.3 29.5 56.0 64.8 94.9 74.9 55.5 117.5 67.0 88.7 47.7 28.7 41.5 71.3 66.8 33.6 35.2 53.3 26.1 66.8 2.1 1.0 2.1 1.4 1.4 0.8 0.8 0.8 1.0 0.9 0.6 0.7 1.0 4.8 1.5 2.4 1.0 1.1 0.8 21.9 21.3 20.0 22.0 23.4 22.8 21.5 22.0 20.2 18.8 22.1 21.9 32.6 105.8 54.2 55.2 34.4 111.4 29.6 30.9 43.3 24.6 54.1 30.5 49.2 40.0 48.2 35.0 31.3 30.4 54.3 34.8 5.9 22.2 243.3 60.6 35.2 44.2 35.4 53.7 63.4 23.8 15.7 37.9 26.5 71.0 48.1 34.1 41.4 44.2 53.4 38.7 61.3 44.4 40.7 133.4 96.4 102.1 37.0 74.5 46.2 67.5 45.7 16.3 32.0 63.3 70.0 34.2 26.2 28.2 33.0 49.0 19.2 22.8 55.4 24.2 19.7 35.2 41.4 37.1 25.8 63.9 122.3 68.3 45.1 37.9 25.0 63.7 WDR27 MGC43690 ENSG00000184465 "WD repeat domain 27" A2RRH5 6 169457212-169702067 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 44.1;Excitatory neurons: 57.2;Inhibitory neurons: 52.6;Oligodendrocyte precursor cells: 51.3;Oligodendrocytes: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037497, HPA037498" Uncertain Enhanced Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA037497: AB_10671503, HPA037498: AB_2675509" "unprognostic (2.10e-1)" "unprognostic (8.66e-3)" "unprognostic (1.32e-1)" "unprognostic (1.78e-2)" "unprognostic (8.59e-2)" "unprognostic (1.98e-3)" "unprognostic (3.81e-3)" "unprognostic (2.59e-2)" "unprognostic (1.83e-1)" "unprognostic (8.63e-2)" "unprognostic (2.43e-2)" "unprognostic (3.62e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (3.15e-2)" "unprognostic (2.19e-1)" "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" 5.1 4.5 2.8 3.1 2.2 2.6 6.7 3.1 3.1 9.5 5.9 6.7 3.4 8.1 4.8 6.3 9.9 3.3 3.5 2.3 2.0 5.0 4.4 4.7 4.1 2.4 2.5 10.9 6.1 3.1 5.1 3.0 2.2 6.8 3.6 2.5 6.2 2.0 4.1 4.7 6.1 2.2 1.7 4.8 5.8 10.5 2.7 3.5 10.0 0.8 3.0 6.4 8.0 2.0 3.8 6.5 17.6 6.4 4.2 8.3 4.4 5.8 1.6 3.5 4.1 6.1 4.8 3.1 3.5 1.8 5.0 8.5 3.1 4.4 5.1 4.0 6.0 6.7 13.4 6.1 2.5 3.3 1.0 4.3 4.1 4.4 3.3 6.5 6.5 7.3 15.6 6.1 4.6 4.9 2.1 12.3 4.6 2.8 3.3 5.0 3.6 5.6 3.3 3.5 7.3 7.5 3.8 3.6 2.1 4.7 4.3 6.1 5.6 4.6 3.7 4.3 5.1 5.8 2.2 7.5 4.2 7.7 4.7 0.0 0.1 0.3 0.3 0.1 0.8 0.3 0.4 0.4 0.1 0.8 1.6 0.2 0.0 0.1 0.1 0.4 0.4 0.3 2.8 2.2 3.1 3.1 2.3 2.0 2.4 2.5 2.2 1.7 2.7 2.0 7.0 9.6 3.9 44.1 6.6 2.2 5.6 6.7 8.0 13.5 8.5 9.0 4.3 7.2 5.4 12.9 6.2 5.2 3.2 3.2 0.0 2.3 28.3 26.9 15.5 7.2 4.2 7.8 57.2 1.5 2.8 7.3 11.2 6.2 3.8 13.7 9.3 4.1 2.2 21.9 52.6 4.7 2.0 2.4 2.5 10.3 8.1 3.4 3.6 38.4 1.4 5.9 4.1 51.3 47.4 2.1 5.7 9.8 4.8 4.3 4.2 2.1 25.7 12.7 0.0 5.2 6.3 21.7 10.7 8.1 1.1 1.9 5.4 6.3 7.0 5.4 WDR3 "DIP2, FLJ12796, UTP12" ENSG00000065183 "WD repeat domain 3" Q9UNX4 1 117929720-117966543 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027509, HPA054354, HPA072915" Enhanced Nucleoplasm,Nucleoli No No "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoli Nucleoplasm "HPA027509: AB_10601808, HPA054354: AB_2682459, HPA072915: " "unprognostic (6.77e-2)" "unprognostic (4.53e-3)" "unprognostic (1.50e-1)" "unprognostic (2.46e-3)" "unprognostic (1.91e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (7.33e-5)" "unprognostic (1.29e-1)" "unprognostic (9.52e-2)" "unprognostic (6.04e-2)" "prognostic unfavorable (8.82e-4)" "unprognostic (8.90e-3)" "unprognostic (7.47e-2)" "unprognostic (5.29e-2)" "unprognostic (1.26e-1)" "unprognostic (1.93e-1)" "unprognostic (8.65e-2)" 9.1 6.3 2.2 8.4 2.8 2.9 9.3 2.8 2.6 7.3 7.4 5.9 5.4 6.7 4.2 6.6 7.4 3.1 4.4 2.6 3.1 5.9 11.2 4.5 7.1 2.2 2.7 7.6 5.1 9.2 3.0 6.2 2.2 5.8 7.7 4.3 4.4 4.9 10.3 5.0 4.9 8.0 2.3 6.2 6.6 11.7 2.7 8.5 6.0 7.4 11.8 9.4 4.3 2.7 35.6 22.2 21.7 33.5 23.0 18.8 24.9 24.1 15.9 27.8 24.3 23.8 11.6 42.4 32.4 18.2 17.7 23.1 55.0 28.4 44.4 34.3 28.1 39.7 22.7 19.0 19.1 74.8 20.0 18.5 19.8 35.4 53.3 16.3 27.2 29.1 49.7 20.2 24.2 20.4 35.9 15.5 78.7 30.7 34.7 33.9 75.5 32.5 13.8 23.4 33.4 30.1 27.8 33.6 39.6 29.6 13.5 29.9 24.0 20.9 33.1 38.4 54.9 29.3 36.8 64.5 30.5 47.2 55.0 0.1 6.8 0.6 9.3 7.1 12.0 9.3 8.4 11.0 13.5 8.6 12.9 11.9 0.6 9.6 8.1 7.4 12.4 7.4 2.2 2.8 2.8 2.6 2.6 3.1 2.2 2.7 2.2 2.3 2.7 2.7 11.4 9.6 14.3 5.9 13.1 20.9 21.9 13.1 15.4 11.3 11.2 9.7 14.9 8.6 23.4 7.3 6.2 10.7 8.6 4.6 9.8 12.8 33.2 11.7 20.4 13.2 3.6 10.7 12.4 13.8 9.9 14.9 8.2 7.5 16.4 11.9 8.9 27.4 7.9 15.2 12.5 6.4 14.2 7.3 5.7 43.6 12.5 7.1 10.6 5.6 8.2 7.4 10.3 13.0 7.5 12.3 4.1 11.7 10.9 31.4 3.0 7.4 17.6 7.3 13.1 23.0 13.8 52.3 50.8 21.7 22.4 5.1 10.6 31.1 9.8 15.4 WDR43 "KIAA0007, NET12, UTP5" ENSG00000163811 "WD repeat domain 43" Q15061 2 28894667-28948219 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 383.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044733 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "HPA044733: AB_10959613" "unprognostic (3.39e-1)" "unprognostic (1.06e-2)" "unprognostic (3.91e-2)" "prognostic unfavorable (5.70e-4)" "unprognostic (2.76e-2)" "unprognostic (3.52e-3)" "prognostic unfavorable (3.66e-5)" "unprognostic (7.00e-2)" "unprognostic (1.94e-2)" "unprognostic (1.60e-1)" "unprognostic (2.33e-3)" "unprognostic (2.66e-2)" "unprognostic (2.56e-3)" "unprognostic (6.20e-2)" "unprognostic (8.66e-2)" "unprognostic (6.30e-2)" "unprognostic (1.11e-1)" 22.1 11.3 7.3 17.5 8.0 42.3 23.6 11.6 8.4 16.5 9.0 16.6 12.1 15.5 9.0 18.2 14.6 12.1 9.6 7.4 8.8 12.3 23.0 11.1 20.3 7.6 7.9 17.0 22.8 15.6 7.4 17.5 8.8 12.1 16.5 13.3 11.5 12.0 55.6 17.6 11.5 19.1 8.4 14.4 12.8 19.8 8.9 18.5 14.5 15.7 24.2 24.2 11.9 10.4 108.5 90.7 42.9 57.0 37.7 47.4 127.1 69.1 44.7 61.4 44.8 92.6 48.6 138.2 50.1 57.9 77.1 54.4 116.6 103.4 98.1 57.9 81.8 122.4 65.5 135.6 57.1 160.9 56.3 49.3 60.5 97.0 164.0 29.3 58.9 52.5 130.2 52.5 54.4 63.7 127.0 89.6 111.0 74.7 59.3 96.3 130.1 95.1 43.4 111.8 61.6 63.8 40.9 67.6 75.1 40.5 30.4 40.5 53.5 63.5 73.1 50.8 118.8 64.2 95.0 383.1 44.2 101.3 60.8 0.4 11.5 8.7 12.5 13.6 22.7 17.3 15.5 14.0 14.8 16.5 19.5 15.0 2.5 22.0 15.5 12.6 14.0 11.7 7.3 8.0 11.6 8.4 7.4 8.8 7.6 7.9 8.8 8.4 8.9 10.4 40.8 51.3 50.7 17.6 54.1 167.7 93.1 41.2 82.0 29.8 53.1 49.7 36.5 37.1 71.5 25.8 22.9 39.0 35.3 21.8 15.6 55.7 88.7 46.1 75.6 40.5 20.9 36.6 28.6 46.2 44.4 56.5 34.7 82.7 45.5 27.5 20.3 49.6 24.3 21.9 29.0 32.1 26.4 21.6 29.6 125.8 37.6 30.3 33.8 30.9 31.8 17.7 27.8 34.2 26.5 55.2 15.7 29.3 42.8 50.8 15.0 19.6 29.7 42.3 6.6 82.7 46.4 33.6 38.6 67.8 148.0 40.4 38.6 41.4 53.8 58.5 WDR81 "CAMRQ2, FLJ33817, PPP1R166, SORF-2" ENSG00000167716 "WD repeat domain 81" Q562E7 17 1716523-1738599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023044, HPA063703" Uncertain Approved Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Vesicles, Cytosol" "HPA023044: AB_1858822, HPA063703: " "unprognostic (1.00e-1)" "unprognostic (4.67e-2)" "unprognostic (6.63e-2)" "unprognostic (4.90e-3)" "unprognostic (6.10e-2)" "unprognostic (7.75e-3)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (3.06e-2)" "unprognostic (1.60e-2)" "prognostic favorable (3.30e-4)" "unprognostic (3.26e-1)" "unprognostic (8.72e-2)" "unprognostic (2.25e-1)" "unprognostic (8.43e-2)" "unprognostic (7.99e-2)" "unprognostic (3.90e-2)" 17.7 16.2 4.5 4.6 5.4 4.9 16.9 4.6 6.3 18.2 6.6 11.5 4.8 18.9 2.4 9.9 17.4 1.6 10.9 4.3 4.4 11.9 32.8 13.7 5.6 5.9 5.1 21.4 11.0 2.4 13.1 3.9 5.3 16.0 1.7 0.8 11.0 5.9 18.2 18.4 17.8 5.1 4.7 24.3 11.0 7.5 6.1 6.6 10.5 2.1 4.2 15.4 13.7 6.4 0.7 12.3 1.7 9.1 12.4 7.0 9.2 0.9 0.2 0.6 0.0 1.8 4.4 4.9 6.5 5.4 6.2 12.2 6.3 8.4 0.4 9.5 12.8 0.3 8.8 5.9 22.1 4.1 7.6 17.8 8.8 5.9 4.1 1.9 5.0 3.7 1.0 6.3 7.6 6.8 1.3 7.6 3.9 4.2 9.4 6.4 2.9 6.8 3.7 2.0 2.2 5.0 4.3 3.4 15.4 0.1 6.0 6.1 6.8 4.8 5.4 7.9 6.7 0.5 1.3 3.1 7.7 5.9 2.4 0.0 1.4 2.8 1.1 2.3 1.3 1.3 1.2 1.2 1.8 1.0 0.8 1.1 0.3 2.1 2.3 3.3 1.2 1.1 4.5 5.4 4.6 6.3 4.3 4.4 5.9 5.1 5.3 4.7 6.1 6.4 6.3 12.8 10.3 6.5 4.2 2.5 2.9 4.4 8.6 4.5 4.8 5.3 3.6 4.3 3.8 0.0 4.2 2.5 9.9 6.8 1.9 3.1 0.7 2.1 6.2 5.4 1.2 14.3 5.3 4.5 1.9 8.2 6.6 2.9 4.5 6.2 4.6 27.7 23.8 5.0 5.3 4.6 10.2 22.3 4.5 1.2 16.4 15.3 0.0 9.4 7.5 2.5 9.2 5.0 7.6 4.8 4.8 15.1 5.3 2.9 8.7 20.1 6.4 1.8 19.7 5.9 4.5 0.7 2.0 3.4 1.7 2.3 4.7 5.8 4.4 1.7 WDR90 "C16orf15, C16orf16, C16orf17, C16orf18, C16orf19, FLJ36483, KIAA1924, POC16" ENSG00000161996 "WD repeat domain 90" Q96KV7 16 649311-667833 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 61.2" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 32.3;Respiratory ciliated cells: 57.6;Rod photoreceptor cells: 34.7;Spermatocytes: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA049362, HPA061785" Approved Approved "Nuclear speckles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "HPA049362: AB_2680728, HPA061785: AB_2684606" "unprognostic (1.97e-2)" "unprognostic (1.50e-2)" "unprognostic (1.72e-1)" "unprognostic (7.34e-3)" "unprognostic (3.89e-2)" "prognostic favorable (2.70e-4)" "unprognostic (2.67e-2)" "unprognostic (8.28e-2)" "unprognostic (5.23e-2)" "unprognostic (1.02e-1)" "unprognostic (9.55e-2)" "unprognostic (9.96e-3)" "unprognostic (2.84e-3)" "unprognostic (8.26e-2)" "unprognostic (3.08e-1)" "unprognostic (4.25e-2)" "unprognostic (4.48e-2)" 8.1 16.3 8.7 3.4 8.8 11.5 10.9 9.5 12.3 17.0 9.9 11.4 5.9 13.3 3.2 10.5 22.1 3.6 9.7 8.9 8.7 16.4 10.9 10.0 4.0 9.2 9.3 21.5 15.7 4.4 25.9 2.5 8.9 15.1 2.2 4.6 9.5 5.5 4.6 9.9 9.3 2.2 8.5 7.4 11.7 61.2 9.1 5.1 22.2 1.4 2.0 10.0 10.5 9.4 10.2 14.1 7.8 18.8 2.9 1.9 0.5 7.4 2.8 5.4 6.3 18.2 14.0 8.8 5.7 2.3 0.1 22.0 3.8 6.0 1.2 15.0 13.7 2.9 57.2 16.9 0.8 15.7 13.4 3.8 4.7 10.8 2.5 2.0 4.0 13.7 1.0 21.9 2.4 7.4 12.5 15.0 7.6 8.4 4.4 34.7 3.1 14.6 6.0 9.4 14.6 15.3 6.8 13.9 1.6 0.5 28.7 12.9 4.3 13.0 13.1 14.3 9.8 22.0 10.4 9.7 3.8 8.5 8.6 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 8.7 8.8 9.5 12.3 8.9 8.7 9.2 9.3 8.9 8.5 9.1 9.4 4.5 0.0 9.1 10.4 1.1 3.4 2.8 4.5 3.4 9.4 9.7 10.4 4.9 14.3 6.9 9.2 14.6 2.8 0.7 10.1 0.0 5.4 5.6 32.3 6.5 4.3 1.2 2.5 5.0 3.8 2.6 5.9 12.2 9.9 0.0 15.1 1.8 4.5 2.7 11.8 5.5 6.9 0.0 0.8 2.5 4.0 6.2 2.2 3.6 5.6 0.3 5.6 0.0 1.5 2.6 4.5 3.1 4.5 1.3 2.7 3.0 2.1 57.6 34.7 6.6 8.3 5.1 34.2 20.7 3.0 2.3 2.5 1.5 8.3 10.8 2.0 WFDC1 PS20 ENSG00000103175 "WAP four-disulfide core domain 1" Q9HC57 16 84294846-84329844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 99.8;seminal vesicle: 115.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.1;Fibroblasts: 72.6;Peritubular cells: 257.3;Smooth muscle cells: 95.8;Theca cells: 325.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 29.8;BJ: 20.5;HEL: 18.2;HeLa: 27.6;THP-1: 9.9;U-937: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031411 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "HPA031411: AB_10600921" "unprognostic (6.53e-2)" "unprognostic (1.27e-1)" "unprognostic (1.61e-2)" "unprognostic (8.66e-4)" "unprognostic (1.41e-2)" "unprognostic (1.50e-3)" "unprognostic (1.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.60e-1)" "unprognostic (2.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.78e-2)" "unprognostic (5.49e-2)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "unprognostic (3.04e-1)" 8.1 26.9 16.5 10.5 16.5 1.9 4.3 19.1 21.2 21.5 12.9 79.3 8.9 17.3 18.8 24.5 7.9 35.1 4.4 16.1 15.5 16.7 5.5 29.5 0.6 17.0 16.2 3.7 1.0 0.4 5.7 99.8 15.3 69.0 17.4 8.4 6.2 115.1 1.2 3.2 14.6 32.2 14.9 3.5 20.8 12.5 16.3 0.3 4.8 1.6 0.8 54.2 13.5 14.9 0.0 0.0 4.4 29.8 0.0 0.1 0.2 20.5 2.5 0.0 0.0 0.0 0.0 0.0 5.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 27.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.5 0.0 0.4 0.0 0.0 2.3 0.0 0.0 5.3 0.1 0.0 0.5 3.2 0.1 0.1 9.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 16.5 19.1 21.2 16.1 15.5 17.0 16.2 15.3 14.9 16.3 14.9 3.4 3.2 0.5 9.1 0.0 1.8 0.9 0.1 0.0 111.1 2.0 0.9 1.4 0.0 0.1 1.8 0.0 2.1 0.1 0.9 11.7 0.0 27.8 0.6 10.6 3.9 4.2 0.0 4.1 0.0 2.0 72.6 7.7 0.5 0.0 0.2 12.5 0.0 6.6 5.0 0.9 4.7 0.0 0.0 3.0 41.1 15.8 2.3 0.0 2.8 0.0 1.4 0.0 29.1 0.6 0.1 0.6 257.3 0.3 1.3 0.4 1.3 0.7 4.2 0.0 1.0 95.8 5.5 0.9 0.1 0.4 3.8 0.5 325.9 3.1 1.0 WFDC10A "C20orf146, dJ688G8.3, WAP10" ENSG00000180305 "WAP four-disulfide core domain 10A" Q9H1F0 20 45629739-45631196 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 439 "epididymis: 288.1" "Cell type enhanced" "Detected in some" "Early spermatids: 1.1;granulocytes: 4.5;Late spermatids: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "thalamus: 1.9" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 288.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WFDC10B WAP12 ENSG00000182931 "WAP four-disulfide core domain 10B" Q8IUB3 20 45684653-45705019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 27.3;retina: 11.7" "Cell type enhanced" "Detected in some" "Astrocytes: 3.6;Early spermatids: 5.5;Late spermatids: 10.1;Microglial cells: 3.7;Rod photoreceptor cells: 9.6;Spermatocytes: 4.8" "Cancer enhanced" "Detected in some" "lung cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "PC-3: 1.9" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.14e-1)" "unprognostic (2.31e-1)" "unprognostic (1.37e-4)" "unprognostic (1.60e-1)" "unprognostic (2.69e-1)" "unprognostic (4.81e-2)" "unprognostic (4.30e-3)" "unprognostic (5.64e-2)" "unprognostic (1.14e-2)" "unprognostic (3.36e-1)" "unprognostic (0.00e+0)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" "unprognostic (2.21e-2)" "unprognostic (3.17e-1)" 0.2 0.0 0.2 0.0 0.2 0.0 0.3 0.2 0.6 0.4 0.2 0.6 0.0 0.3 27.3 0.1 0.4 0.2 0.1 0.2 0.1 0.1 0.0 0.7 0.0 0.5 0.6 0.1 0.0 0.0 0.1 0.4 0.3 0.7 0.5 11.7 0.0 0.2 0.0 1.2 0.2 0.4 0.4 0.0 0.3 4.3 0.2 0.2 0.0 0.0 0.0 5.9 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.6 1.9 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.6 0.2 0.1 0.5 0.6 0.3 0.4 0.2 0.3 0.0 0.0 0.5 3.6 0.0 0.0 0.1 0.4 0.0 0.2 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.3 0.0 0.1 0.0 0.0 1.3 0.4 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 1.3 0.4 2.0 0.0 0.0 10.1 0.0 0.0 0.0 3.7 0.0 0.9 0.0 1.5 0.9 1.2 0.1 0.0 0.0 0.4 0.3 0.0 0.0 9.6 0.0 0.0 0.1 4.8 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.7 WFDC11 WAP11 ENSG00000180083 "WAP four-disulfide core domain 11" Q8NEX6 20 45648563-45670270 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 18 "epididymis: 93.8" "Cell type enriched" "Detected in some" 12 "Early spermatids: 55.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "basophil: 2.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.3" "Group enriched" "Detected in some" 5 "HeLa: 8.7;RPMI-8226: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" 0.0 0.4 0.8 0.2 0.5 2.9 0.3 2.9 2.4 0.1 0.8 0.2 0.0 0.2 93.8 0.2 0.2 0.5 0.1 0.4 0.5 0.2 0.3 0.1 0.2 0.5 0.1 0.2 0.2 0.1 0.0 0.2 0.6 0.4 0.0 2.0 0.6 0.1 0.1 1.5 0.2 0.1 0.0 0.2 0.3 5.0 0.4 0.0 0.3 0.0 0.1 0.2 0.0 3.0 0.1 0.7 0.0 0.1 0.4 0.5 0.8 0.7 0.1 0.0 0.0 0.5 0.2 0.4 0.2 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.5 0.8 8.7 0.5 0.0 0.4 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.3 0.4 0.1 0.0 0.1 0.3 0.7 0.7 0.2 0.4 0.1 0.3 5.3 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.7 0.0 0.1 0.4 0.2 0.1 0.3 0.3 0.0 0.0 1.4 0.2 2.3 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.3 0.3 0.0 0.2 0.0 0.0 0.8 0.5 2.9 2.4 0.4 0.5 0.5 0.1 0.6 0.0 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.8 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 WFDC12 "C20orf122, dJ211D12.4, WAP2" ENSG00000168703 "WAP four-disulfide core domain 12" Q8WWY7 20 45123425-45124465 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 42.0" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 2.6;Collecting duct cells: 5.5" "Group enriched" "Detected in many" 7 "head and neck cancer: 18.9;melanoma: 14.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 86000 "Cluster 31: Skin - Epidermis development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "unprognostic (1.18e-2)" "unprognostic (5.42e-2)" "unprognostic (2.25e-1)" "unprognostic (2.86e-1)" "unprognostic (3.40e-3)" "unprognostic (1.72e-2)" "unprognostic (8.70e-3)" "prognostic unfavorable (5.65e-4)" "unprognostic (4.49e-2)" "unprognostic (3.91e-1)" "unprognostic (5.50e-3)" 0.1 0.1 1.2 0.1 0.7 1.0 2.5 0.2 1.1 0.8 0.4 0.2 0.5 0.2 1.8 6.7 0.1 0.2 0.0 1.0 0.2 0.3 0.2 1.1 0.2 0.3 0.2 0.2 0.0 0.1 0.0 0.1 0.6 1.8 0.2 0.7 2.1 2.9 0.6 42.0 0.2 0.2 0.0 0.2 0.1 1.7 0.7 1.2 0.3 0.0 1.5 0.1 9.8 0.5 0.2 0.1 0.0 0.1 0.9 0.1 0.3 0.1 0.4 0.0 0.4 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.0 0.2 0.6 0.4 0.0 0.0 0.3 0.3 0.3 0.0 0.3 0.0 0.0 0.3 0.2 0.4 0.3 0.1 0.2 0.3 0.3 0.1 0.1 0.3 0.4 0.4 0.1 0.0 0.5 0.1 0.5 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.7 0.0 0.0 0.1 0.3 0.3 0.3 0.3 0.3 0.2 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 0.2 1.1 1.0 0.2 0.3 0.2 0.6 0.0 0.7 0.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.5 5.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 WFDC13 "C20orf138, dJ601O1.3, WAP13" ENSG00000168634 "WAP four-disulfide core domain 13" Q8IUB5 20 45702038-45708817 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "epididymis: 89.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Rod photoreceptor cells: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (2.53e-1)" "unprognostic (1.30e-2)" "unprognostic (7.84e-3)" "unprognostic (7.96e-3)" "unprognostic (2.04e-1)" "unprognostic (1.02e-11)" "unprognostic (1.17e-1)" "unprognostic (1.44e-2)" "unprognostic (2.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 89.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 WFDC2 "dJ461P17.6, EDDM4, HE4, WAP5" ENSG00000101443 "WAP four-disulfide core domain 2" Q14508 20 45469753-45481532 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartic protease inhibitor, Protease inhibitor, Serine protease inhibitor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 5211.9;salivary gland: 1988.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 4507.8;Club cells: 6299.8;Collecting duct cells: 1988.1;Endometrial ciliated cells: 3253.3;Glandular and luminal cells: 4817.5;Respiratory ciliated cells: 2935.3;Urothelial cells: 3783.3" "Group enriched" "Detected in all" 4 "endometrial cancer: 1815.6;ovarian cancer: 1086.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "A-431: 115.8;CAPAN-2: 210.6;EFO-21: 171.3;HaCaT: 151.9;RPTEC TERT1: 165.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042302 Enhanced "Secreted in other tissues" NA NA 1600000 "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA042302: AB_2677939" "unprognostic (5.75e-2)" "unprognostic (2.23e-1)" "unprognostic (4.37e-2)" "unprognostic (2.99e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (7.19e-3)" "unprognostic (1.94e-1)" "unprognostic (5.49e-3)" "unprognostic (3.71e-1)" "unprognostic (2.01e-1)" "unprognostic (1.42e-1)" "unprognostic (1.40e-1)" "prognostic favorable (4.44e-5)" "unprognostic (1.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.00e-1)" "unprognostic (3.20e-2)" 16.8 1.6 6.7 11.0 14.1 0.0 81.2 6.6 9.3 5211.9 22.3 163.7 9.6 240.0 941.9 54.9 676.7 166.1 6.0 7.2 7.5 909.9 23.6 144.7 0.9 7.7 9.1 10.4 30.5 81.9 152.4 0.7 7.1 221.7 224.9 6.9 1988.3 825.3 2.0 38.2 60.1 28.9 6.9 0.7 44.1 14.9 7.2 12.3 253.8 0.5 8.8 161.2 25.0 7.3 115.8 0.0 0.3 0.4 0.0 0.1 4.7 0.0 0.0 0.0 0.0 4.9 210.6 0.0 171.3 0.0 0.7 151.9 0.0 0.0 0.0 0.8 1.9 0.0 1.2 0.3 0.0 0.2 0.7 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 6.7 0.3 2.7 18.4 0.6 0.0 0.1 0.0 0.0 165.6 1.3 5.0 1.0 10.6 0.0 1.1 2.0 3.1 0.6 0.0 0.3 2.8 0.6 0.5 0.7 0.6 1.6 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.7 14.1 6.6 9.3 7.2 7.5 7.7 9.1 7.1 6.9 7.2 7.3 2.8 169.9 273.8 2.6 4.2 8.9 1190.9 4507.8 35.3 30.3 340.4 238.5 2.0 94.4 6299.8 1988.1 22.9 1.0 4.3 239.8 221.1 308.2 1.6 3253.3 359.3 21.7 422.7 0.0 4.7 129.2 0.8 23.4 31.6 4817.5 10.1 12.5 3.9 3.3 1.9 0.0 7.6 1764.7 1328.5 0.6 1.1 5.0 36.1 26.8 10.6 1.9 5.7 31.3 0.0 2.0 3.4 179.0 424.6 0.0 0.8 1169.7 1.7 113.9 2935.3 6.1 6.6 1.1 319.1 12.4 11.9 110.2 14.1 0.7 36.8 0.0 318.2 3783.3 WFDC3 "dJ447F3.3, WAP14" ENSG00000124116 "WAP four-disulfide core domain 3" Q8IUB2 20 45747944-45791932 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 16.7;testis: 20.0" "Group enriched" "Detected in many" 5 "Early spermatids: 115.9;Late spermatids: 222.8;Spermatocytes: 108.1" "Cancer enhanced" "Detected in many" "lung cancer: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "PC-3: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted in male reproductive system" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (7.47e-2)" "unprognostic (1.94e-1)" "unprognostic (2.64e-1)" "unprognostic (2.39e-2)" "unprognostic (1.06e-1)" "unprognostic (5.75e-2)" "unprognostic (9.30e-4)" "unprognostic (6.63e-3)" "unprognostic (4.02e-2)" "unprognostic (1.47e-1)" "unprognostic (1.69e-3)" "unprognostic (1.79e-1)" "unprognostic (1.36e-8)" "unprognostic (8.53e-2)" "unprognostic (2.45e-1)" "unprognostic (5.27e-3)" "unprognostic (3.03e-2)" 0.3 0.0 0.5 0.1 0.6 0.0 1.2 0.6 0.5 0.0 0.4 0.2 0.3 0.1 0.8 0.0 0.6 0.0 0.0 0.5 0.5 0.2 0.0 0.1 0.0 0.6 0.9 0.0 0.1 0.0 0.1 0.0 0.6 0.1 0.1 0.3 0.0 0.2 0.0 16.7 0.0 0.9 0.8 0.0 0.0 20.0 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.6 0.5 0.5 0.5 0.6 0.9 0.6 0.8 0.6 0.6 0.5 0.0 2.6 0.7 0.1 1.1 5.9 2.7 0.0 1.2 2.4 1.8 0.8 0.0 12.3 3.7 6.2 0.4 0.0 5.7 11.7 2.5 115.9 17.6 0.7 0.2 3.6 0.0 0.6 10.0 1.8 2.1 3.1 3.4 1.3 1.7 2.9 0.9 1.1 0.0 0.6 12.1 24.4 0.6 0.8 222.8 1.5 1.3 0.0 0.0 0.3 2.2 0.0 1.0 0.8 13.1 2.0 2.6 0.0 6.2 5.8 5.9 9.0 28.7 0.0 0.5 1.5 108.1 2.6 1.5 3.1 0.0 0.4 0.4 1.1 14.3 WFDC5 "dJ211D12.5, WAP1" ENSG00000175121 "WAP four-disulfide core domain 5" Q8TCV5 20 45109452-45115172 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 393.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 55.8;Early spermatids: 17.6;Late spermatids: 10.4;Suprabasal keratinocytes: 43.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.32e-1)" "unprognostic (3.22e-2)" "unprognostic (3.05e-1)" "unprognostic (1.54e-1)" "unprognostic (1.28e-4)" "unprognostic (6.59e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.32e-5)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.96e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.1 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.6 1.5 1.2 393.9 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.6 0.0 0.0 13.3 0.3 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 55.8 0.4 2.5 0.6 0.0 0.1 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.1 0.0 0.0 17.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 10.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 3.0 43.2 0.0 0.1 0.0 0.1 0.2 WFDC6 "C20orf171, dJ461P17.11, WAP6" ENSG00000243543 "WAP four-disulfide core domain 6" Q9BQY6 20 45534196-45539482 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "epididymis: 250.9" "Cell type enriched" "Detected in some" 4 "Respiratory ciliated cells: 34.2" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.9;testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "U-87 MG: 2.6" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.68e-3)" "unprognostic (2.21e-3)" "unprognostic (1.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.91e-2)" 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.4 1.0 0.0 0.0 0.0 0.2 250.9 0.1 7.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.5 0.1 0.0 0.0 0.0 0.0 37.6 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 6.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 34.2 0.0 0.0 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 WFDC8 "C20orf170, dJ461P17.1, WAP8" ENSG00000158901 "WAP four-disulfide core domain 8" Q8IUA0 20 45551153-45579326 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 518 "epididymis: 410.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "U-87 MG: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042710, HPA071119" Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "HPA042710: AB_2732501, HPA071119: AB_2732172" "unprognostic (5.63e-3)" "unprognostic (1.09e-2)" "unprognostic (2.34e-1)" "unprognostic (9.96e-2)" "unprognostic (1.07e-2)" 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 410.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 WFIKKN1 "C16orf12, RJD2, WFDC20A, WFIKKN" ENSG00000127578 "WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1" Q96NZ8 16 629239-634117 "Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.3" "Cell type enhanced" "Detected in some" "Astrocytes: 4.9;Horizontal cells: 10.1;Melanocytes: 3.6" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 4.4;Hep G2: 1.0;NTERA-2: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in other tissues" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (3.12e-1)" "unprognostic (2.57e-1)" "unprognostic (3.17e-2)" "unprognostic (1.59e-2)" "unprognostic (3.55e-1)" "unprognostic (2.28e-2)" "unprognostic (3.36e-2)" "unprognostic (4.45e-2)" "unprognostic (8.53e-2)" "unprognostic (2.43e-1)" "unprognostic (3.78e-3)" "unprognostic (1.19e-1)" "unprognostic (5.56e-3)" "unprognostic (1.53e-1)" "unprognostic (3.02e-1)" "unprognostic (2.50e-3)" "unprognostic (4.70e-5)" 0.2 0.1 0.3 0.0 0.4 0.0 0.1 1.5 0.8 0.4 0.0 0.3 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.3 0.0 2.3 0.8 0.4 0.0 0.2 0.0 0.6 1.1 0.0 1.2 0.0 0.1 0.8 0.0 0.0 0.3 0.0 0.5 1.0 0.3 0.0 0.0 0.6 0.5 1.0 0.1 0.0 0.5 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.5 0.8 0.3 0.0 0.2 0.0 0.1 0.0 0.1 0.5 0.4 0.0 0.5 4.9 0.1 0.9 0.2 0.5 0.6 2.9 0.7 0.8 0.8 0.0 0.3 0.0 0.0 0.2 0.2 2.2 0.0 0.0 0.1 1.3 1.9 0.9 1.2 0.0 1.4 0.2 0.1 0.3 0.0 1.8 1.3 1.4 0.7 0.9 0.1 10.1 0.5 1.4 0.0 0.6 0.0 0.1 0.0 0.2 3.6 1.0 0.0 1.1 0.0 1.0 1.1 0.7 2.4 0.7 0.0 0.7 2.1 0.4 1.4 0.1 0.0 0.7 0.4 1.6 0.7 1.4 1.6 0.3 0.2 0.3 1.4 0.3 WFIKKN2 "WFDC20B, WFIKKNRP" ENSG00000173714 "WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2" Q8TEU8 17 50834650-50842353 "Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 41 "choroid plexus: 578.0;ovary: 146.2" "Group enriched" "Detected in some" 11 "Leydig cells: 9.0;Peritubular cells: 24.0" "Group enriched" "Detected in some" 5 "glioma: 0.7;testis cancer: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "medulla oblongata: 12.6;midbrain: 5.1;thalamus: 6.1" "Secreted in other tissues" NA NA 4500000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" "unprognostic (7.31e-2)" "unprognostic (7.31e-2)" "unprognostic (1.31e-2)" "unprognostic (4.80e-2)" "unprognostic (3.46e-2)" "unprognostic (5.72e-2)" "unprognostic (5.42e-3)" "unprognostic (2.54e-3)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (2.19e-1)" "unprognostic (4.08e-3)" "unprognostic (1.42e-3)" "unprognostic (2.17e-1)" "unprognostic (2.75e-2)" "unprognostic (1.14e-1)" 0.1 1.3 2.6 0.0 1.7 0.0 0.1 5.3 1.7 0.3 578.0 1.0 0.0 1.1 0.5 0.2 0.8 0.2 0.7 8.7 0.8 0.1 0.0 0.2 0.0 1.4 1.1 146.2 0.3 0.0 2.2 0.0 1.5 0.4 0.0 0.3 0.1 0.6 2.1 0.9 0.2 0.3 0.8 0.0 0.2 2.4 6.5 0.5 0.0 0.9 0.0 0.1 0.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.7 5.3 1.7 8.7 0.8 1.4 1.1 1.5 0.8 6.5 1.8 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 9.0 0.1 0.0 0.0 0.0 1.5 0.0 0.5 0.1 0.0 0.0 24.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 WIF1 ENSG00000156076 "WNT inhibitory factor 1" Q9Y5W5 12 65050626-65121305 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 599.7" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 2736.1" "Group enriched" "Detected in many" 5 "endometrial cancer: 16.9;lung cancer: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.2;LHCN-M2: 1.0;NTERA-2: 3.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.96e-3)" "unprognostic (2.00e-1)" "unprognostic (4.29e-3)" "unprognostic (3.26e-3)" "unprognostic (9.66e-2)" "unprognostic (1.91e-1)" "unprognostic (1.26e-2)" "unprognostic (7.94e-2)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (3.17e-1)" "unprognostic (2.30e-5)" "unprognostic (3.02e-1)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (7.24e-3)" 1.3 2.7 22.4 0.3 34.3 0.0 22.9 16.3 44.6 1.6 15.0 0.3 0.0 8.6 23.8 4.7 1.5 0.0 0.5 24.8 35.4 0.7 0.0 117.4 0.1 16.6 16.5 1.2 0.3 0.0 46.5 0.0 16.2 14.2 0.3 599.7 45.1 2.8 0.1 6.6 2.2 0.9 16.5 0.1 1.4 0.7 23.4 0.2 0.0 0.7 0.0 1.7 2.2 18.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 34.3 16.3 44.6 24.8 35.4 16.6 16.5 16.2 16.5 23.4 18.4 0.0 35.3 197.8 186.1 0.0 12.6 34.5 0.0 2.2 25.0 0.7 13.7 1.6 0.0 26.6 1.8 8.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 4.7 0.0 0.0 0.6 0.0 0.0 27.8 0.5 0.1 7.6 1.0 0.0 0.0 0.0 15.2 46.5 0.0 0.0 0.0 20.4 0.0 0.0 0.8 23.2 12.2 0.0 2736.1 0.0 1.5 0.9 0.0 0.0 0.4 0.2 25.5 0.0 1.2 34.2 80.8 0.0 1.8 1.5 2.5 2.0 0.4 10.5 0.0 1.2 0.0 0.0 0.8 WNK2 "KIAA1760, NY-CO-43, PRKWNK2, SDCCAG43" ENSG00000165238 "WNK lysine deficient protein kinase 2" Q9Y3S1 9 93184916-93320572 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 83.1;skeletal muscle: 62.3" "Cell type enhanced" "Detected in many" "Astrocytes: 76.4;Cone photoreceptor cells: 160.6;Excitatory neurons: 128.5;Inhibitory neurons: 98.8;Intestinal goblet cells: 77.3;Rod photoreceptor cells: 106.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 18.8;Hep G2: 31.0;SCLC-21H: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015555, HPA016519, CAB017813" Enhanced Approved Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB017813: , HPA015555: AB_2669218, HPA016519: AB_2669380" "unprognostic (5.02e-2)" "unprognostic (1.32e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-1)" "unprognostic (1.01e-1)" "unprognostic (2.04e-1)" "unprognostic (1.79e-3)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.31e-3)" "unprognostic (2.23e-1)" "unprognostic (4.48e-3)" "unprognostic (6.51e-2)" "unprognostic (1.44e-1)" "unprognostic (4.38e-4)" "unprognostic (1.62e-1)" 2.0 3.0 14.9 3.3 14.8 0.0 4.9 4.6 39.1 4.7 0.3 36.0 17.9 5.8 4.2 5.7 15.4 1.3 83.1 18.3 7.7 0.8 1.3 0.9 0.5 13.8 6.0 1.1 42.8 2.3 29.6 3.0 8.8 16.7 11.9 28.8 47.3 12.3 62.3 15.8 21.5 4.5 1.9 2.7 14.7 6.6 14.2 7.1 1.8 31.0 1.0 5.5 3.4 10.5 7.4 6.6 4.6 13.2 0.0 0.0 8.8 0.0 0.0 0.1 0.0 2.7 0.2 18.8 2.4 0.0 1.3 0.3 10.4 0.0 0.0 0.0 12.1 0.0 5.8 31.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 12.2 0.0 0.0 9.8 0.2 0.2 11.5 7.2 0.4 0.0 0.0 15.3 0.0 1.1 37.6 14.8 2.4 10.2 0.9 1.3 1.3 2.2 0.1 0.0 4.8 0.2 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 14.9 14.8 4.6 39.1 18.3 7.7 13.8 6.0 8.8 1.9 14.2 10.5 0.3 0.0 0.0 76.4 0.3 1.3 8.5 3.1 0.0 62.0 19.4 18.7 58.1 31.5 14.1 0.0 160.6 15.5 0.2 34.3 0.0 17.1 1.2 7.7 9.2 1.3 32.4 0.0 128.5 9.1 6.7 2.7 3.6 15.8 0.0 8.6 0.4 0.2 3.4 1.7 98.8 77.3 6.1 1.3 2.2 2.6 0.9 0.1 1.8 29.0 0.6 60.3 0.0 9.0 3.2 3.2 57.0 6.0 0.2 11.1 47.7 1.1 6.6 106.8 13.1 3.5 5.0 0.7 7.7 1.1 5.5 15.6 0.4 0.1 59.0 8.9 WNT1 INT1 ENSG00000125084 "Wnt family member 1" P04628 12 48978322-48982620 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Osteogenesis imperfecta, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 4.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.1;Gastric mucus-secreting cells: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basal ganglia: 4.5;cerebral cortex: 2.1" "Group enriched" "Detected in some" 8 "gdT-cell: 3.1;MAIT T-cell: 5.1;memory CD4 T-cell: 2.0;memory CD8 T-cell: 2.9;naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 29 "T-cells: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" "Secreted to extracellular matrix" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.02e-2)" "unprognostic (5.80e-3)" "unprognostic (1.23e-1)" "unprognostic (1.64e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-3)" "unprognostic (5.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.63e-1)" "unprognostic (1.20e-1)" "unprognostic (4.08e-2)" "unprognostic (4.97e-2)" "unprognostic (1.32e-2)" "unprognostic (1.67e-2)" "unprognostic (1.70e-1)" "unprognostic (7.35e-3)" "unprognostic (2.76e-2)" 0.0 0.0 0.8 0.5 4.5 1.1 0.0 0.0 2.1 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.2 0.1 0.7 0.2 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.3 0.7 0.3 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 5.1 0.1 2.0 2.9 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.2 0.5 0.8 4.5 0.0 2.1 0.7 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 WNT10B "SHFM6, WNT-12" ENSG00000169884 "Wnt family member 10B" O00744 12 48965340-48971735 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.3;Extravillous trophoblasts: 21.7;Fibroblasts: 4.8;Inhibitory neurons: 4.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 7.3;T-47d: 8.2;U-266/84: 7.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA055048, HPA062539" Enhanced Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA055048: AB_2682683, HPA062539: AB_2684793" "unprognostic (1.13e-1)" "unprognostic (2.14e-2)" "unprognostic (5.73e-4)" "unprognostic (2.27e-2)" "unprognostic (3.09e-2)" "unprognostic (3.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.14e-1)" "unprognostic (4.99e-3)" "unprognostic (3.05e-2)" "unprognostic (5.39e-6)" "unprognostic (4.29e-2)" "unprognostic (3.74e-2)" "unprognostic (4.50e-1)" "unprognostic (1.25e-1)" 1.5 0.2 13.1 1.5 14.9 1.2 0.6 4.2 17.9 0.8 3.2 1.4 1.4 0.3 1.5 1.4 1.0 0.5 1.5 15.3 7.3 0.4 0.4 1.1 1.7 8.6 7.6 0.2 0.3 0.1 2.4 0.3 8.2 0.8 0.7 0.1 0.9 0.6 0.7 3.4 4.3 0.1 5.1 4.1 1.1 3.3 10.4 1.9 1.0 0.4 1.5 1.3 1.0 9.8 1.9 1.2 0.0 1.7 0.0 0.0 4.6 1.3 2.4 0.5 0.1 3.6 4.0 0.0 0.3 0.2 1.5 2.2 4.8 0.3 0.2 1.1 6.3 2.1 1.7 0.1 0.0 0.7 2.9 0.0 0.4 0.1 2.1 4.1 0.0 1.5 7.3 0.3 0.7 2.4 0.1 2.5 0.0 1.3 2.5 0.0 0.6 2.2 0.0 0.4 0.1 0.0 0.3 0.1 0.6 2.2 8.2 2.7 0.0 2.5 4.9 0.4 0.6 2.6 7.8 0.0 1.0 5.4 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 13.1 14.9 4.2 17.9 15.3 7.3 8.6 7.6 8.2 5.1 10.4 9.8 0.2 0.0 0.0 0.7 0.2 0.4 0.0 0.0 1.8 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.8 0.2 0.1 0.0 0.0 0.0 7.3 0.0 21.7 4.8 0.0 0.1 0.0 0.0 0.7 0.0 0.3 0.0 4.7 0.2 0.0 0.0 1.2 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.7 3.0 0.9 1.3 1.4 1.6 0.0 0.0 0.1 WNT11 ENSG00000085741 "Wnt family member 11" O96014 11 76186325-76210736 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.4" "Group enriched" "Detected in some" 5 "Adipocytes: 41.5;Fibroblasts: 23.2;Theca cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "NK-cell: 2.9" "Lineage enriched" "Detected in single" 6 "NK-cells: 2.9" "Cell line enhanced" "Detected in some" "BEWO: 36.2;CACO-2: 12.1;CAPAN-2: 17.8;EFO-21: 57.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA050101 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA050101: AB_2681015" "prognostic favorable (5.97e-4)" "unprognostic (9.27e-2)" "unprognostic (2.01e-2)" "unprognostic (2.52e-1)" "unprognostic (1.87e-2)" "unprognostic (8.43e-2)" "unprognostic (7.88e-2)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (3.85e-2)" "unprognostic (2.88e-2)" "unprognostic (4.36e-2)" "unprognostic (3.10e-1)" "unprognostic (2.37e-2)" "unprognostic (2.87e-1)" "unprognostic (3.16e-3)" "unprognostic (1.09e-3)" 37.4 20.8 1.7 0.4 3.5 0.9 23.7 4.1 2.2 4.8 14.3 3.6 2.5 2.7 1.3 1.2 6.7 2.1 8.3 3.8 3.5 2.8 8.0 6.3 1.1 7.4 2.7 4.5 9.5 1.2 3.1 4.1 6.9 4.3 1.1 0.3 4.3 1.1 12.3 8.1 3.3 0.6 2.8 3.5 1.4 0.9 2.8 0.9 17.2 7.1 0.2 4.0 3.8 2.1 0.0 0.0 0.0 0.0 2.9 0.2 36.2 0.0 0.0 0.1 0.2 12.1 17.8 0.0 57.0 0.1 0.2 5.5 1.1 0.0 0.0 5.5 2.1 2.9 1.4 2.2 0.0 0.0 0.4 0.1 1.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 1.4 0.3 0.0 0.4 0.9 0.0 2.9 0.4 0.0 2.1 0.2 0.0 2.5 0.1 1.4 0.0 0.0 2.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.2 1.7 3.5 4.1 2.2 3.8 3.5 7.4 2.7 6.9 2.8 2.8 2.1 41.5 0.0 0.0 0.3 0.5 1.3 0.5 0.0 1.2 0.0 0.9 1.9 4.7 0.0 0.0 0.0 0.0 0.9 2.3 2.2 0.0 0.0 0.0 5.0 2.9 1.8 0.0 0.0 0.2 0.2 3.3 23.2 0.0 1.1 0.0 0.4 0.7 2.5 0.1 0.0 0.5 0.5 0.0 0.3 2.3 0.0 0.0 0.7 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 2.6 0.7 0.7 0.1 3.8 0.0 0.0 0.0 0.0 1.8 5.7 0.4 0.5 0.1 0.9 1.4 0.9 24.3 1.5 0.1 WNT16 ENSG00000002745 "Wnt family member 16" Q9UBV4 7 121325367-121341104 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 6.0;skin 1: 20.5" "Cell type enhanced" "Detected in some" "B-cells: 4.6;Basal keratinocytes: 10.1;Endometrial stromal cells: 3.6;Inhibitory neurons: 6.0;Microglial cells: 3.7;Plasma cells: 2.6;Suprabasal keratinocytes: 11.5" "Cancer enhanced" "Detected in some" "lung cancer: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 145 "memory B-cell: 15.6;naive B-cell: 15.4" "Lineage enriched" "Detected in single" 146 "B-cells: 15.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.3;HEK 293: 5.4;hTEC/SVTERT24-B: 1.6;U-2197: 2.6;U-266/70: 1.6" "Low region specificity" "Detected in single" "Region enhanced" "Detected in some" "spinal cord: 4.4" "Secreted to extracellular matrix" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (6.53e-2)" "unprognostic (3.63e-2)" "unprognostic (7.24e-2)" "unprognostic (1.90e-2)" "unprognostic (2.94e-3)" "unprognostic (5.23e-2)" "unprognostic (1.77e-2)" "unprognostic (1.16e-1)" "unprognostic (1.12e-1)" "unprognostic (1.94e-1)" "unprognostic (3.77e-1)" "unprognostic (2.18e-2)" "unprognostic (3.57e-10)" "unprognostic (5.89e-3)" "unprognostic (2.73e-1)" "unprognostic (5.50e-2)" "unprognostic (1.66e-1)" 0.2 0.3 0.3 0.3 0.6 0.0 1.4 0.2 0.4 6.0 0.5 0.5 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.4 0.2 0.1 0.2 0.3 1.1 0.2 0.2 0.0 0.1 0.0 0.3 0.4 0.1 0.6 0.1 0.1 0.1 1.8 0.1 20.5 0.5 0.2 0.3 0.8 0.2 0.1 0.0 0.1 0.1 0.0 0.4 0.1 3.2 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.2 0.0 0.5 0.1 0.5 0.0 0.0 0.0 0.0 5.4 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.3 1.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 15.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.6 0.2 0.4 0.4 0.2 0.2 0.2 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 4.6 10.1 0.1 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 3.6 0.1 0.0 0.4 0.1 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 3.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 11.5 0.0 0.1 0.0 0.1 0.0 WNT2 "INT1L1, IRP" ENSG00000105989 "Wnt family member 2" P09544 7 117275451-117323152 "Cancer-related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 39.9" "Cell type enhanced" "Detected in some" "Early spermatids: 30.9;Endometrial stromal cells: 33.1;Fibroblasts: 82.5;Late spermatids: 14.7;Spermatocytes: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-2197: 11.5" "Region enhanced" "Detected in many" "basal ganglia: 12.6" "Low region specificity" "Detected in many" HPA020920 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA020920: AB_1858850" "unprognostic (1.90e-1)" "unprognostic (6.97e-2)" "unprognostic (2.88e-2)" "unprognostic (4.11e-3)" "unprognostic (9.14e-2)" "unprognostic (2.47e-1)" "unprognostic (2.54e-2)" "unprognostic (2.75e-1)" "unprognostic (2.74e-1)" "unprognostic (5.70e-2)" "unprognostic (1.36e-2)" "unprognostic (1.41e-1)" "unprognostic (3.43e-1)" "unprognostic (4.05e-2)" "unprognostic (2.50e-2)" "unprognostic (1.05e-1)" "unprognostic (2.10e-1)" 1.2 0.0 0.2 0.1 0.4 0.0 0.8 0.1 0.7 3.5 0.3 0.1 0.0 8.6 0.1 0.0 0.8 0.2 0.4 0.4 0.3 0.1 0.5 6.9 0.0 0.1 0.5 0.3 0.1 0.0 0.1 39.9 0.1 3.2 0.0 0.0 0.0 0.4 0.0 0.7 0.0 1.1 0.1 0.9 0.0 0.5 1.5 0.0 0.1 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.7 0.4 0.3 0.1 0.5 0.1 0.1 1.5 0.2 0.5 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 1.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 30.9 0.8 33.1 9.8 0.0 0.0 1.4 0.0 3.6 82.5 0.0 0.6 0.0 0.0 10.8 0.6 7.7 0.0 0.5 0.0 0.0 0.8 0.3 14.7 1.5 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 13.6 0.5 0.0 2.7 9.0 0.2 0.0 0.0 0.2 WNT3 "INT4, MGC131950, MGC138321, MGC138323" ENSG00000108379 "Wnt family member 3" P56703 17 46762506-46833154 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 12.3;skin 1: 27.7" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 44.5;Early spermatids: 27.7;Late spermatids: 63.8;Suprabasal keratinocytes: 17.6" "Cancer enriched" "Detected in many" 6 "testis cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 8.5;U-698: 14.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA049893: " "unprognostic (1.84e-1)" "unprognostic (2.90e-2)" "unprognostic (2.35e-1)" "unprognostic (6.41e-4)" "unprognostic (4.73e-2)" "unprognostic (5.26e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (4.97e-2)" "unprognostic (2.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "unprognostic (1.10e-8)" "unprognostic (1.77e-1)" "unprognostic (2.08e-1)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" 0.8 0.4 1.3 0.4 1.1 0.1 1.0 0.7 1.0 1.0 0.2 0.6 3.4 0.5 0.0 1.3 0.5 0.1 0.9 0.8 1.2 1.7 12.3 0.9 0.2 1.4 1.8 0.5 0.8 2.5 1.7 0.2 1.2 1.3 0.2 0.2 1.2 0.0 0.2 27.7 2.7 0.2 0.7 0.7 0.4 4.4 4.4 0.1 1.3 0.0 0.1 0.4 1.1 0.7 3.9 1.7 8.5 0.0 0.1 0.1 0.7 0.8 0.9 3.0 0.0 2.7 1.7 1.6 2.3 2.1 6.1 1.3 0.4 0.0 3.9 0.0 0.4 0.0 3.0 2.3 0.0 0.1 0.1 0.2 1.8 1.1 2.3 3.5 1.1 2.5 1.5 0.0 1.0 1.7 0.0 1.4 0.0 1.0 2.4 2.9 1.9 0.2 0.6 0.0 0.1 0.7 1.6 0.0 1.2 2.1 0.0 4.0 0.2 3.2 2.1 0.4 1.5 0.6 0.2 14.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 1.1 0.7 1.0 0.8 1.2 1.4 1.8 1.2 0.7 4.4 0.7 0.2 0.0 1.5 3.9 0.5 44.5 0.6 0.6 3.4 1.1 3.0 1.7 1.3 1.5 0.4 0.0 0.0 2.2 0.1 0.7 1.9 0.7 27.7 0.1 0.7 0.5 0.0 0.0 5.4 2.5 0.1 1.1 0.0 0.2 0.0 0.7 0.4 4.0 0.2 8.4 4.3 0.6 0.0 0.0 1.5 63.8 0.3 0.1 1.8 1.0 0.6 0.2 0.0 4.0 1.1 2.9 1.4 0.4 0.0 1.2 3.7 0.5 0.3 0.8 0.0 1.4 1.1 0.9 2.9 0.8 17.6 0.3 0.0 0.3 0.9 0.3 WNT3A ENSG00000154342 "Wnt family member 3A" P56704 1 228006998-228061271 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 15.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Basal keratinocytes: 3.4;Basal prostatic cells: 3.1;Basal squamous epithelial cells: 8.6;Syncytiotrophoblasts: 2.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HEK 293: 1.1;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 9: U-2 OS - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049893: " "unprognostic (9.84e-3)" "prognostic favorable (6.11e-5)" "unprognostic (2.40e-1)" "unprognostic (3.37e-1)" "unprognostic (7.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.96e-1)" "unprognostic (4.22e-2)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (4.80e-3)" "unprognostic (1.99e-1)" "unprognostic (7.26e-2)" "unprognostic (5.43e-3)" "unprognostic (1.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 1.3 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 3.4 3.1 1.2 8.6 0.0 0.0 0.1 1.9 0.0 0.9 1.8 0.0 2.0 0.0 0.4 0.0 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.5 1.0 2.9 0.0 0.0 0.1 0.5 WNT5A hWNT5A ENSG00000114251 "Wnt family member 5A" P41221 3 55465715-55490539 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 27.4;salivary gland: 34.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Basal squamous epithelial cells: 34.7;Club cells: 31.3;Endometrial stromal cells: 101.6;Oligodendrocyte precursor cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 227.2;BJ hTERT+: 315.4;HeLa: 242.1;SiHa: 354.2;U-87 MG: 248.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (2.34e-3)" "unprognostic (1.35e-1)" "prognostic favorable (2.94e-5)" "unprognostic (1.37e-1)" "unprognostic (3.45e-3)" "unprognostic (1.14e-1)" "unprognostic (2.16e-2)" "unprognostic (3.91e-2)" "unprognostic (5.89e-2)" "unprognostic (9.58e-2)" "unprognostic (8.34e-3)" "unprognostic (1.10e-1)" "unprognostic (4.81e-3)" "unprognostic (9.70e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-3)" "unprognostic (3.63e-2)" 2.3 0.8 1.9 3.1 1.9 0.1 4.9 1.7 1.8 5.7 0.6 3.1 3.5 27.4 3.1 16.9 6.7 7.2 1.6 2.5 3.2 2.7 2.6 4.9 2.2 3.9 4.3 9.1 4.3 1.0 1.8 10.8 3.0 4.6 3.2 1.2 34.4 8.3 2.0 2.4 3.8 5.9 3.8 4.0 3.5 1.8 3.1 2.4 2.8 1.7 5.1 18.7 12.1 5.4 0.0 0.4 20.8 0.2 15.8 37.7 0.0 227.2 315.4 46.3 80.4 1.3 0.0 6.6 0.6 132.2 19.5 0.2 10.0 0.2 48.2 0.0 6.2 6.4 242.1 0.1 35.1 0.0 0.4 25.0 5.9 139.2 7.6 22.5 0.1 0.2 0.0 109.5 113.3 0.0 0.1 0.1 11.1 0.5 13.6 0.0 14.1 1.0 6.2 7.6 0.0 1.0 354.2 43.1 0.0 18.0 0.1 0.0 0.0 76.1 13.2 70.0 18.2 25.8 0.0 2.4 248.5 0.3 35.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.9 1.7 1.8 2.5 3.2 3.9 4.3 3.0 3.8 3.1 5.4 1.1 51.3 23.2 4.2 0.0 1.5 1.6 1.4 34.7 13.2 12.1 4.4 4.3 0.0 31.3 12.9 0.0 3.0 0.0 0.2 0.0 0.2 15.8 13.3 101.6 4.3 0.0 0.0 3.0 0.2 0.6 19.9 0.0 13.9 2.5 8.5 1.1 2.6 1.3 0.0 9.0 0.3 10.2 2.4 1.3 4.2 19.6 2.6 0.0 5.6 4.2 1.6 0.0 31.2 0.1 0.4 2.5 30.1 0.1 0.9 2.3 1.0 1.9 1.4 0.0 1.6 7.7 0.1 1.1 17.5 1.6 1.5 1.5 6.5 1.6 9.6 WNT5B ENSG00000111186 "Wnt family member 5B" Q9H1J7 12 1529891-1647212 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 32.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 25.6;Microglial cells: 19.7;Muller glia cells: 40.4;Urothelial cells: 16.2" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;eosinophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 231.4;BJ hTERT+: 143.5;BJ hTERT+ SV40 Large T+: 165.4;BJ hTERT+ SV40 Large T+ RasG12V: 136.4;fHDF/TERT166: 162.6;HBF TERT88: 144.1;hTEC/SVTERT24-B: 144.8;U-138 MG: 142.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061991 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA061991: " "unprognostic (7.44e-2)" "unprognostic (5.59e-2)" "unprognostic (8.14e-2)" "unprognostic (3.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (5.53e-3)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (4.08e-2)" "unprognostic (2.16e-2)" "unprognostic (1.49e-3)" "unprognostic (1.90e-1)" "unprognostic (2.93e-2)" "unprognostic (2.77e-1)" "unprognostic (2.71e-2)" 3.0 2.3 3.6 4.1 4.1 0.5 3.0 2.8 3.7 5.5 1.8 24.6 4.3 7.2 5.0 14.9 6.2 2.8 4.0 2.8 5.3 1.9 4.6 3.0 2.6 4.7 3.9 8.2 1.5 9.0 11.2 3.9 4.6 32.4 5.8 5.4 15.7 20.0 1.4 5.3 5.0 5.4 3.9 5.2 6.4 1.8 4.2 3.7 2.0 6.7 3.0 13.9 9.7 3.1 0.3 0.1 1.4 0.2 34.6 61.2 0.0 231.4 143.5 165.4 136.4 8.7 0.9 2.9 0.4 162.6 111.1 3.5 3.3 0.0 144.1 55.0 7.9 12.8 0.0 0.0 8.5 0.2 0.1 51.3 3.3 144.8 41.3 66.6 0.0 0.1 9.5 51.9 39.4 0.1 0.0 0.3 5.7 0.2 0.5 0.0 2.3 4.0 2.0 0.0 1.0 3.2 4.9 0.5 0.2 17.7 0.2 0.9 0.0 142.4 5.9 56.7 119.7 13.9 2.2 0.7 13.9 0.0 1.5 0.0 1.8 1.5 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 3.6 4.1 2.8 3.7 2.8 5.3 4.7 3.9 4.6 3.9 4.2 3.1 0.9 0.0 0.6 7.5 1.5 0.9 11.0 1.9 25.6 1.8 0.7 6.5 2.2 0.0 3.3 0.0 0.0 1.0 0.2 2.4 0.0 1.1 0.2 1.7 10.4 1.4 0.0 0.0 6.9 0.7 1.1 8.0 0.5 2.7 0.0 0.3 0.4 1.7 5.3 0.0 7.9 1.9 2.0 2.1 2.9 0.5 2.1 2.7 3.6 19.7 4.1 40.4 0.0 4.0 5.6 2.8 5.0 2.6 4.5 8.8 1.0 0.2 4.3 2.7 6.6 7.9 4.3 0.7 5.7 7.7 1.3 0.7 0.2 0.0 1.7 16.2 WNT6 ENSG00000115596 "Wnt family member 6" Q9Y6F9 2 218859805-218874233 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enriched" "Detected in some" 4 "Sertoli cells: 92.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 8.7" "Region enhanced" "Detected in many" "basal ganglia: 10.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "BEWO: 34.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 7.7" HPA070759 Approved "Secreted to extracellular matrix" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" "HPA070759: AB_2732164" "unprognostic (1.86e-2)" "unprognostic (6.03e-2)" "unprognostic (5.14e-2)" "unprognostic (2.06e-1)" "unprognostic (5.32e-2)" "unprognostic (7.34e-2)" "unprognostic (8.08e-3)" "unprognostic (4.73e-2)" "unprognostic (1.27e-2)" "unprognostic (1.19e-1)" "unprognostic (1.21e-2)" "unprognostic (2.66e-1)" "unprognostic (1.24e-3)" "unprognostic (5.26e-2)" "unprognostic (4.82e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" 3.5 0.6 1.1 0.1 10.0 0.0 3.5 0.3 4.2 4.3 0.5 7.4 0.1 2.4 0.0 1.3 3.2 0.0 3.4 0.9 0.8 1.1 0.3 0.3 0.1 1.0 1.1 3.1 0.8 0.0 2.0 2.0 1.1 3.1 0.0 0.1 1.1 0.1 1.1 2.6 2.8 0.0 0.5 7.2 2.7 3.6 2.5 0.0 1.1 0.0 0.1 1.9 3.7 0.2 0.0 0.0 0.0 1.2 0.0 0.0 34.4 0.0 0.0 0.0 0.0 3.3 0.5 0.0 3.7 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 5.0 1.7 0.0 0.0 3.7 0.1 4.7 0.0 0.0 2.7 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.1 10.0 0.3 4.2 0.9 0.8 1.0 1.1 1.1 0.5 2.5 0.2 2.5 0.0 0.0 0.0 1.6 0.5 21.0 1.1 0.6 3.5 1.4 8.5 0.6 0.0 0.1 0.0 0.0 7.9 0.0 0.0 0.0 0.1 3.4 0.4 3.1 5.9 0.0 0.0 0.2 0.0 1.6 2.0 0.0 0.1 0.0 0.4 2.5 0.0 0.8 1.7 0.1 0.0 0.0 0.0 0.3 4.5 0.0 0.3 1.8 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.4 3.1 5.5 0.0 0.0 0.0 2.0 92.1 0.3 15.5 16.9 0.3 0.2 0.1 0.7 0.2 0.1 0.0 1.3 WNT7B ENSG00000188064 "Wnt family member 7B" P56706 22 45920366-45977162 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.4;skin 1: 17.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.6;Basal prostatic cells: 26.4;Basal squamous epithelial cells: 42.1;Club cells: 23.9;Pancreatic endocrine cells: 43.3;Prostatic glandular cells: 26.2;Urothelial cells: 46.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 119.4;HeLa: 103.7;RPTEC TERT1: 41.4;SK-BR-3: 51.0;U-87 MG: 93.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (2.02e-3)" "unprognostic (7.83e-3)" "unprognostic (8.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-2)" "unprognostic (1.31e-1)" "unprognostic (1.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.05e-2)" "unprognostic (3.85e-3)" "unprognostic (1.69e-2)" "unprognostic (8.58e-4)" "unprognostic (1.90e-1)" "unprognostic (6.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-2)" 0.0 0.0 4.6 0.0 3.4 0.0 1.1 1.8 5.1 3.5 0.4 0.0 0.0 0.1 0.1 12.4 1.2 2.9 0.0 4.9 4.5 6.3 0.1 3.1 0.0 2.7 2.3 0.0 0.5 0.1 0.5 0.4 4.3 4.4 0.0 0.0 2.2 1.9 0.0 17.9 0.0 0.0 1.7 0.0 0.0 0.3 5.4 0.7 0.3 0.0 1.0 9.1 8.3 1.9 23.2 119.4 0.3 0.0 0.0 0.0 15.2 0.4 1.3 0.0 0.0 0.5 15.5 0.1 3.7 0.2 1.3 25.8 0.9 15.1 0.0 0.1 1.0 0.0 103.7 0.6 0.0 0.0 0.1 0.0 10.2 0.1 3.0 0.4 0.0 0.0 0.0 0.2 0.0 33.1 0.0 0.0 0.1 9.7 22.4 0.0 0.0 1.3 41.4 33.9 4.3 0.0 10.3 51.0 0.0 0.2 8.5 13.6 0.0 2.1 1.8 0.0 1.0 0.0 0.0 0.0 93.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 3.4 1.8 5.1 4.9 4.5 2.7 2.3 4.3 1.7 5.4 1.9 0.3 6.4 15.6 3.9 0.5 33.6 26.4 16.3 42.1 0.5 4.0 0.6 1.6 8.6 23.9 12.9 4.2 3.5 0.1 0.1 0.0 5.9 0.3 1.7 0.4 0.7 0.0 0.0 0.3 0.5 0.3 1.7 0.0 4.3 2.5 0.2 0.4 0.1 0.1 0.0 1.2 0.0 0.0 0.0 3.7 0.2 0.3 0.3 0.0 1.0 1.0 0.2 0.0 7.5 0.1 43.3 0.0 0.4 1.5 26.2 0.0 0.1 13.8 1.1 0.0 0.8 1.9 0.2 1.8 21.0 20.5 0.7 0.5 0.0 0.0 46.6 WNT8A WNT8D ENSG00000061492 "Wnt family member 8A" Q9H1J5 5 138083990-138092365 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.8;Inhibitory neurons: 1.5;Microglial cells: 1.0" "Cancer enriched" "Detected in single" 12 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA038539 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038539: AB_10669646" "unprognostic (1.11e-5)" "unprognostic (4.11e-2)" "unprognostic (4.11e-2)" "unprognostic (5.32e-2)" 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WNT8B ENSG00000075290 "Wnt family member 8B" Q93098 10 100463009-100483744 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "parathyroid gland: 1.2" "Cell type enhanced" "Detected in single" "Oligodendrocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.3;JURKAT: 3.1;RPMI-8226: 1.0;SCLC-21H: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036570 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA036570: AB_10670113" "unprognostic (6.92e-2)" "unprognostic (1.57e-1)" "unprognostic (7.13e-2)" "unprognostic (6.67e-2)" "unprognostic (3.88e-1)" "unprognostic (1.90e-1)" "unprognostic (2.64e-1)" "unprognostic (9.16e-4)" "unprognostic (1.95e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "unprognostic (7.83e-2)" "unprognostic (2.42e-3)" "unprognostic (5.02e-2)" "unprognostic (1.63e-1)" "unprognostic (2.68e-2)" "unprognostic (1.24e-2)" 0.0 0.8 0.1 0.0 0.4 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.4 1.2 0.1 0.0 0.0 0.2 0.0 0.9 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.6 0.8 0.0 0.0 0.0 0.1 0.2 0.0 1.0 0.0 0.7 1.1 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WNT9A WNT14 ENSG00000143816 "Wnt family member 9A" O14904 1 227918656-227947932 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.7;skeletal muscle: 26.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 5.1;Ionocytes: 6.1;Respiratory ciliated cells: 12.5;Urothelial cells: 5.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 16.2;PC-3: 10.8;RH-30: 16.4;SCLC-21H: 14.9;SiHa: 14.7;U-2197: 10.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (2.27e-2)" "unprognostic (3.24e-1)" "unprognostic (3.77e-3)" "unprognostic (4.57e-2)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (2.39e-2)" "unprognostic (1.44e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.48e-1)" "unprognostic (1.38e-2)" "unprognostic (1.70e-2)" "unprognostic (3.72e-2)" "unprognostic (8.71e-2)" "unprognostic (5.04e-2)" "unprognostic (9.93e-2)" 3.3 1.4 0.4 1.1 0.6 0.1 3.0 0.6 0.8 4.1 7.7 18.7 1.3 5.3 0.4 5.8 5.5 2.1 10.1 0.7 0.9 0.9 0.2 3.9 0.3 1.2 0.9 9.8 2.8 1.2 2.8 2.1 2.1 2.5 1.1 0.0 2.4 1.0 26.3 1.1 6.0 4.3 0.5 1.0 5.9 1.5 0.7 1.1 2.0 2.8 0.3 4.9 3.4 0.5 1.0 3.3 0.4 0.1 0.4 0.7 8.1 1.1 0.9 0.1 0.0 0.0 8.8 0.0 4.7 1.5 3.3 16.2 0.4 0.8 0.0 1.6 0.6 0.0 6.0 0.2 0.4 0.0 0.5 0.1 4.0 0.1 0.1 0.3 1.0 0.0 0.0 0.1 1.8 2.2 0.0 0.0 1.0 0.0 10.8 0.2 16.4 1.7 4.6 1.1 14.9 0.0 14.7 6.6 0.0 5.2 8.4 1.8 0.6 2.1 1.3 10.4 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.6 0.8 0.7 0.9 1.2 0.9 2.1 0.5 0.7 0.5 0.3 3.2 0.6 0.3 0.0 0.9 1.3 3.6 0.0 0.0 3.1 1.3 1.4 0.0 4.3 1.8 0.0 0.3 0.2 0.8 0.0 0.7 0.1 2.1 2.1 0.4 3.0 0.0 0.7 1.3 0.2 5.1 1.5 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 2.9 6.1 0.0 0.4 0.1 4.4 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.9 1.1 0.0 4.5 0.1 1.8 0.1 0.1 12.5 0.0 0.0 1.3 1.1 0.0 1.8 3.9 0.3 0.0 0.2 0.1 0.1 5.3 WNT9B "WNT14B, WNT15" ENSG00000158955 "Wnt family member 9B" O14905 17 46833201-46886730 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 14.0;seminal vesicle: 9.7" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Microglial cells: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SuSa: 7.4" "Region enriched" "Detected in single" 7 "thalamus: 5.8" "Low region specificity" "Detected in all" "HPA058361, HPA059572" Approved "Secreted to extracellular matrix" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA058361: AB_2683691, HPA059572: AB_2684067" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (3.18e-2)" "unprognostic (7.48e-3)" "unprognostic (3.37e-3)" "unprognostic (1.78e-1)" "unprognostic (8.11e-2)" "unprognostic (1.59e-2)" "unprognostic (3.66e-2)" "unprognostic (6.19e-4)" "unprognostic (1.13e-1)" "unprognostic (3.69e-2)" "unprognostic (7.52e-4)" "unprognostic (1.27e-1)" "unprognostic (2.70e-1)" "unprognostic (1.37e-1)" 0.3 0.3 0.6 0.0 1.0 0.1 0.3 0.3 0.8 0.1 0.0 0.0 1.7 0.2 1.2 0.1 0.1 0.1 0.5 0.4 0.6 3.2 0.7 0.2 0.1 0.7 1.3 0.0 0.1 14.0 0.0 0.6 0.3 0.1 0.0 0.1 0.0 9.7 0.1 2.4 0.9 0.2 0.5 1.0 0.0 0.1 2.3 0.0 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.6 1.0 0.3 0.8 0.4 0.6 0.7 1.3 0.3 0.5 2.3 0.5 0.1 0.0 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 WSCD1 KIAA0523 ENSG00000179314 "WSC domain containing 1" Q658N2 17 6057807-6124427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.5" "Cell type enhanced" "Detected in many" "Early spermatids: 73.4;Late spermatids: 99.6;Oligodendrocyte precursor cells: 110.1" "Cancer enriched" "Detected in many" 4 "glioma: 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 40.0;HUVEC TERT2: 24.7;OE19: 26.4;PC-3: 24.8;RH-30: 50.5;SCLC-21H: 15.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015919 Uncertain Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Golgi apparatus" "HPA015919: AB_2216211" "unprognostic (1.50e-1)" "unprognostic (7.10e-2)" "unprognostic (5.32e-2)" "unprognostic (1.15e-2)" "unprognostic (2.61e-1)" "unprognostic (4.18e-2)" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (3.59e-2)" "unprognostic (1.69e-1)" "unprognostic (3.46e-4)" "unprognostic (2.08e-1)" "unprognostic (1.18e-2)" "unprognostic (4.13e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (1.62e-2)" 2.2 2.2 19.7 1.0 21.7 0.0 1.8 29.5 19.8 1.1 6.8 6.8 3.4 1.2 0.2 0.6 1.0 0.9 2.0 18.1 19.1 5.9 0.5 1.4 1.3 29.4 23.8 0.5 1.5 0.9 3.5 4.8 24.9 0.6 3.8 5.7 1.2 0.7 11.4 1.3 4.3 1.3 22.2 13.6 1.3 11.2 22.9 1.1 0.9 3.8 0.9 0.8 0.8 26.7 0.0 5.8 40.0 3.2 0.2 0.0 2.1 4.3 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 10.0 0.3 0.0 0.0 13.6 0.0 0.0 0.3 0.3 0.0 0.0 0.2 0.0 0.0 0.5 0.0 24.7 0.1 0.0 0.9 1.2 0.8 0.0 0.0 13.3 26.4 24.8 0.0 50.5 1.6 8.4 2.1 15.5 0.0 0.2 0.0 0.0 4.1 0.0 0.3 0.1 0.0 1.4 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 21.7 29.5 19.8 18.1 19.1 29.4 23.8 24.9 22.2 22.9 26.7 7.7 0.0 0.0 11.8 0.1 0.4 0.0 0.0 0.6 24.1 0.2 0.1 3.8 0.0 0.0 1.8 0.0 0.7 0.1 22.4 1.9 0.3 73.4 0.1 0.0 5.9 0.0 0.0 2.7 0.2 0.1 0.2 0.0 0.0 0.0 0.7 10.0 0.4 1.2 1.7 12.5 3.3 0.0 0.8 0.4 99.6 0.6 0.0 1.8 4.7 0.0 9.8 0.0 110.1 20.6 0.2 6.5 0.0 0.0 0.0 21.5 1.4 0.0 3.5 0.0 6.0 0.7 0.4 3.3 0.1 0.6 0.0 0.3 0.1 5.8 0.1 WSCD2 KIAA0789 ENSG00000075035 "WSC domain containing 2" Q2TBF2 12 108129288-108250537 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.7;thyroid gland: 16.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 43.7;Excitatory neurons: 30.1;Horizontal cells: 21.9;Inhibitory neurons: 27.7;Oligodendrocyte precursor cells: 9.5" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "RT4: 32.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013346, HPA048133" Approved Uncertain Nucleoplasm "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA013346: AB_1858865, HPA048133: AB_2797236" "unprognostic (1.50e-1)" "unprognostic (1.64e-3)" "unprognostic (1.50e-2)" "unprognostic (4.27e-3)" "unprognostic (1.68e-1)" "unprognostic (3.43e-1)" "unprognostic (1.80e-2)" "unprognostic (3.43e-3)" "unprognostic (3.03e-2)" "unprognostic (3.05e-1)" "unprognostic (3.15e-1)" "unprognostic (7.43e-2)" "unprognostic (5.99e-2)" "unprognostic (3.73e-2)" "unprognostic (2.11e-1)" "unprognostic (2.32e-3)" "unprognostic (7.62e-3)" 0.9 0.7 8.9 0.1 14.3 0.0 0.8 36.7 13.9 3.5 0.3 3.3 0.3 10.1 2.1 1.0 2.6 0.1 0.4 17.9 4.2 1.0 0.0 0.3 0.1 0.6 2.4 0.3 1.4 0.0 1.4 0.2 2.2 4.2 0.3 11.9 0.3 13.5 0.2 0.8 0.7 6.8 2.7 0.1 1.9 0.2 10.0 0.0 16.8 0.4 0.1 2.5 1.3 7.2 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.4 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 8.9 14.3 36.7 13.9 17.9 4.2 0.6 2.4 2.2 2.7 10.0 7.2 0.8 0.0 0.0 5.9 0.6 0.1 0.0 0.1 0.0 43.7 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.0 30.1 0.0 0.0 1.6 3.1 0.0 0.0 0.0 0.7 0.0 0.0 21.9 27.7 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 2.8 0.0 0.3 0.0 9.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.2 0.3 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 WWC1 "KIAA0869, KIBRA, PPP1R168" ENSG00000113645 "WW and C2 domain containing 1" Q8IX03 5 168291645-168472303 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 142.3" "Cell type enhanced" "Detected in many" "Astrocytes: 162.2;Cone photoreceptor cells: 91.8;Endometrial ciliated cells: 81.8;Glandular and luminal cells: 149.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 120.2;RPTEC TERT1: 260.4;SK-BR-3: 136.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038016, HPA038017" Approved Approved "Golgi apparatus" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA038016: AB_10697091, HPA038017: AB_10669513" "unprognostic (3.60e-1)" "unprognostic (2.24e-2)" "unprognostic (1.08e-1)" "unprognostic (9.92e-2)" "unprognostic (1.51e-1)" "unprognostic (6.77e-3)" "unprognostic (2.89e-1)" "unprognostic (3.50e-2)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (3.31e-2)" "unprognostic (7.38e-2)" "prognostic favorable (1.95e-8)" "unprognostic (2.81e-3)" "unprognostic (1.80e-1)" "unprognostic (2.77e-1)" "unprognostic (1.50e-1)" 7.8 0.6 41.8 2.9 43.3 0.1 21.2 41.0 39.7 6.0 50.4 6.4 24.3 2.8 6.8 22.9 17.2 8.7 1.6 40.3 41.3 73.3 38.1 20.2 3.0 56.8 47.0 0.8 28.3 23.5 7.8 10.2 43.6 16.4 6.1 17.8 142.3 11.8 0.0 19.9 20.2 1.1 46.6 0.7 22.9 1.7 54.3 1.3 29.7 0.0 6.9 9.3 10.1 38.6 50.6 56.4 9.2 0.4 0.0 0.0 96.8 3.7 0.9 17.1 15.3 120.2 73.6 0.0 58.6 1.2 47.4 35.0 18.9 46.1 20.1 0.1 18.6 0.0 28.6 29.9 0.9 4.4 0.0 6.0 13.9 32.3 28.5 13.2 0.0 3.0 0.0 7.2 1.3 56.4 0.0 0.1 13.3 60.8 8.2 0.0 0.4 29.1 260.4 68.8 30.7 11.4 66.5 136.4 17.1 11.6 67.8 4.3 0.0 3.0 34.2 0.4 36.9 0.8 0.4 0.2 3.4 0.1 8.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.8 43.3 41.0 39.7 40.3 41.3 56.8 47.0 43.6 46.6 54.3 38.6 0.3 64.1 72.3 162.2 1.3 11.9 14.7 6.0 1.8 1.4 35.7 25.7 1.8 34.3 42.1 58.8 91.8 11.6 0.6 17.9 13.7 44.9 0.4 81.8 10.8 1.3 7.8 0.0 50.1 40.5 2.3 5.3 15.3 149.2 1.3 5.6 1.1 16.9 1.3 0.0 27.9 7.8 6.1 0.6 1.1 0.1 1.2 4.2 10.6 8.4 1.1 18.1 0.0 17.6 1.9 73.1 10.9 0.7 0.1 38.8 18.9 61.8 36.7 9.1 0.0 0.2 5.6 0.3 5.0 7.3 13.9 18.2 2.1 2.5 12.2 16.5 XBP1 XBP2 ENSG00000100219 "X-box binding protein 1" P17861 22 28794555-28800597 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Angiogenesis, Apoptosis, Autophagy, Differentiation, Lipid biosynthesis, Lipid metabolism, Myogenesis, Protein transport, Stress response, Transcription, Transcription regulation, Transport, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 1159.0" "Cell type enhanced" "Detected in all" "Breast glandular cells: 1756.7;Plasma cells: 2344.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 960.5;SK-BR-3: 870.0;T-47d: 1012.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" 100.3 103.7 23.8 150.1 25.9 247.2 720.6 26.8 27.7 369.7 46.8 203.6 163.7 94.2 150.5 85.2 126.5 120.2 75.8 22.5 32.2 87.7 687.3 151.8 138.3 33.3 33.2 67.5 1159.0 195.1 87.7 107.9 29.0 228.8 196.5 21.1 849.4 152.1 90.1 72.2 140.3 105.5 30.8 213.2 259.9 22.2 33.0 148.2 168.9 48.7 307.8 250.4 52.2 30.8 77.1 50.8 71.4 111.0 132.2 144.2 181.1 130.9 223.2 128.4 168.8 82.5 104.4 290.2 63.0 121.8 75.3 104.5 134.2 64.4 110.4 130.0 84.9 88.3 42.6 356.2 285.9 166.1 80.8 90.7 378.2 85.2 363.7 115.9 104.1 35.0 79.5 355.0 78.6 960.5 23.3 157.0 49.7 594.6 79.0 168.6 78.5 401.5 118.4 105.4 94.7 90.7 79.0 870.0 358.6 94.8 1012.9 188.5 59.8 73.3 69.8 78.5 47.3 598.8 456.8 174.8 98.0 210.0 112.3 185.0 27.1 23.5 73.3 14.1 95.2 38.0 52.4 76.5 23.5 43.8 52.9 43.2 2.1 88.5 10.1 75.0 20.5 38.5 23.8 25.9 26.8 27.7 22.5 32.2 33.3 33.2 29.0 30.8 33.0 30.8 116.4 86.6 195.6 3.6 379.0 210.6 410.2 192.2 47.3 25.4 1756.7 829.4 46.2 205.9 390.1 138.0 131.3 112.8 298.6 171.2 80.3 240.6 30.2 160.1 147.8 107.0 189.7 68.6 8.5 633.3 335.4 220.0 208.0 293.6 99.7 55.1 93.1 654.5 267.9 15.2 11.4 633.0 225.9 130.0 281.5 22.7 95.7 172.3 355.8 18.7 95.0 18.6 385.2 8.0 7.3 328.4 190.5 64.7 2344.9 381.9 247.0 73.2 168.9 53.2 13.1 144.4 179.3 36.8 32.5 86.2 202.0 349.7 206.1 34.8 260.0 355.3 XCL1 "ATAC, LPTN, LTN, SCM-1, SCM-1a, SCYC1" ENSG00000143184 "X-C motif chemokine ligand 1" P47992 1 168576605-168582069 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.6" "Group enriched" "Detected in many" 4 "dendritic cells: 185.3;T-cells: 213.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 14 "NK-cell: 88.5" "Lineage enriched" "Detected in many" 14 "NK-cells: 88.5" "Cell line enhanced" "Detected in some" "CACO-2: 2.8;Hep G2: 4.1;SCLC-21H: 3.3;SuSa: 6.1;U-266/70: 5.0;U-266/84: 1.9" "Not detected" "Not detected" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 63: NK-cells & T-cells - Immune response" "HPA057725: AB_2683511" "unprognostic (5.38e-3)" "unprognostic (5.72e-2)" "unprognostic (8.23e-3)" "unprognostic (4.19e-3)" "unprognostic (1.43e-1)" "unprognostic (6.10e-2)" "unprognostic (2.96e-1)" "unprognostic (4.27e-2)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (4.61e-1)" "unprognostic (8.85e-2)" "unprognostic (5.34e-10)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (5.47e-2)" "unprognostic (2.15e-2)" 0.5 0.1 0.1 1.0 0.1 3.5 1.0 0.0 0.2 1.0 0.0 0.7 1.0 2.2 0.8 0.2 0.6 1.1 0.5 0.1 0.2 0.5 2.6 1.8 2.3 0.1 0.1 0.2 0.5 0.0 0.1 2.2 0.2 0.4 1.0 0.0 1.5 0.3 0.1 0.1 1.5 0.3 0.1 4.6 1.2 0.2 0.6 4.1 0.3 0.0 1.6 0.9 0.4 0.1 0.9 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.3 0.0 0.3 0.0 0.0 6.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 5.0 1.9 0.0 0.0 0.0 0.0 3.2 0.0 0.0 6.2 0.0 0.2 0.0 1.0 5.9 0.0 0.0 0.3 4.0 0.3 88.5 0.0 0.0 0.0 1.7 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.1 0.6 0.1 2.3 3.2 5.5 0.0 1.5 4.0 0.5 0.0 2.2 0.0 1.3 1.5 2.0 1.5 0.0 0.0 0.0 1.4 185.3 0.7 0.0 0.0 1.3 2.0 1.9 1.9 0.0 8.4 0.0 0.2 1.2 1.9 8.2 2.9 2.5 0.0 1.4 0.9 0.4 0.0 0.1 0.8 0.0 1.9 10.6 0.0 0.0 3.1 39.2 0.0 0.1 0.0 42.2 0.0 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.1 0.0 0.0 0.0 0.3 1.7 0.2 0.2 1.8 4.3 0.8 213.4 0.0 0.4 0.1 XCL2 "SCM-1b, SCYC2" ENSG00000143185 "X-C motif chemokine ligand 2" Q9UBD3 1 168540768-168543997 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 13.4" "Group enriched" "Detected in many" 10 "dendritic cells: 513.6;NK-cells: 277.1;T-cells: 240.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "NK-cell: 423.5" "Lineage enriched" "Detected in many" 8 "NK-cells: 423.5" "Cell line enhanced" "Detected in some" "CACO-2: 3.0;RT4: 1.1;SuSa: 1.1" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA057725: AB_2683511" "unprognostic (9.88e-3)" "unprognostic (7.89e-3)" "unprognostic (4.77e-2)" "unprognostic (9.32e-3)" "unprognostic (8.21e-2)" "unprognostic (6.79e-4)" "unprognostic (9.33e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.58e-3)" "unprognostic (6.26e-2)" "unprognostic (2.02e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (8.36e-9)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "unprognostic (3.02e-2)" "unprognostic (1.06e-1)" 1.1 0.8 0.3 3.2 0.3 14.1 0.9 0.3 0.5 1.0 0.4 1.9 3.2 3.6 0.9 0.6 1.8 1.9 0.7 0.3 0.4 0.4 5.6 3.3 5.6 0.5 0.3 0.4 0.6 0.3 0.2 1.4 0.4 0.5 1.5 0.0 1.9 1.0 0.3 0.1 2.0 1.4 0.4 13.4 2.9 0.3 0.6 3.8 0.6 0.5 3.6 2.0 0.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.4 0.1 0.4 47.2 0.2 2.7 0.3 3.6 50.1 0.3 0.1 2.1 37.1 1.9 423.5 0.3 0.1 0.0 17.1 0.3 0.3 0.3 0.5 0.3 0.4 0.5 0.3 0.4 0.4 0.6 0.4 2.9 0.0 1.1 0.0 3.3 2.4 0.0 0.0 1.8 0.0 1.6 1.4 0.8 0.0 0.0 0.0 0.0 0.1 513.6 0.3 0.0 0.1 0.0 2.4 2.0 1.0 0.0 19.2 0.0 0.0 0.0 1.1 8.2 2.2 1.3 0.0 1.4 0.6 0.4 0.0 0.0 0.7 0.0 5.0 4.0 0.0 0.0 3.7 33.8 0.0 0.8 0.0 277.1 0.0 0.0 0.0 1.1 0.0 13.2 0.0 0.0 0.2 0.0 0.0 0.0 0.4 2.3 0.0 0.0 0.9 1.1 0.0 240.6 0.0 0.1 0.1 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 166.6;kidney: 156.0" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 475.9" "Cancer enhanced" "Detected in many" "liver cancer: 18.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cell line enhanced" "Detected in some" "ASC diff: 8.2;ASC TERT1: 40.1;HSkMC: 21.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 13000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 7.5 0.9 0.1 3.7 0.1 0.2 3.0 0.1 0.1 3.7 0.1 5.5 99.0 2.4 0.1 2.2 6.3 4.3 5.3 0.1 0.1 156.0 23.1 2.1 0.5 0.2 0.1 1.8 0.3 0.3 0.1 1.2 0.1 1.8 6.3 0.0 1.5 0.4 0.5 4.4 166.6 6.0 0.1 0.3 3.4 0.1 0.1 1.0 1.4 2.4 0.4 7.8 4.0 0.1 0.0 0.0 0.5 0.0 8.2 40.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 4.3 1.4 1.2 0.0 1.3 2.8 0.2 0.2 0.4 2.0 0.1 0.0 2.8 0.4 1.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.2 0.5 11.4 5.9 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.2 0.0 0.0 10.0 1.1 0.0 0.0 0.0 0.4 18.5 0.8 0.0 0.3 12.8 0.0 1.0 3.6 0.0 0.0 1.0 1.8 1.0 0.0 0.0 3.1 0.0 0.1 0.0 21.0 0.0 0.1 0.0 475.9 75.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.0 1.2 0.9 0.0 8.4 0.0 XPO6 "FLJ22519, KIAA0370, RANBP20" ENSG00000169180 "Exportin 6" Q96QU8 16 28097976-28211965 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 202.1" "Lineage enriched" "Detected in all" 9 "granulocytes: 202.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038246 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "Plasma membrane, Cytosol" "HPA038246: AB_10674550" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.31e-2)" "unprognostic (4.48e-1)" "unprognostic (1.40e-1)" "unprognostic (1.01e-3)" "unprognostic (2.10e-1)" "unprognostic (5.36e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (8.80e-4)" 48.0 48.3 70.0 55.9 73.7 92.0 39.9 61.7 87.0 43.7 63.9 47.0 21.8 42.3 18.8 57.0 44.8 24.5 36.2 72.2 72.0 47.2 62.1 70.9 62.9 76.1 69.2 36.6 43.2 26.9 56.6 25.7 73.6 48.6 27.4 35.2 44.9 20.1 29.9 52.9 63.0 26.8 67.8 160.6 42.8 100.3 72.9 51.1 50.5 13.7 44.9 44.9 46.0 77.8 82.9 63.3 54.8 58.8 37.2 58.8 57.9 97.0 98.0 124.8 124.8 89.1 61.7 59.8 78.6 99.8 63.3 53.8 131.6 83.9 151.5 115.3 72.1 67.6 90.0 101.6 87.9 95.4 70.8 46.3 61.2 111.1 108.9 53.5 73.1 63.4 118.0 31.0 86.0 101.1 116.2 116.1 88.1 43.6 55.4 101.0 64.3 101.2 46.8 45.2 103.3 55.0 52.9 88.3 47.8 60.8 62.7 63.3 75.4 104.1 64.4 87.2 84.8 63.0 83.8 89.8 78.7 98.4 89.1 21.1 9.9 32.9 14.2 11.4 15.4 20.7 16.5 15.8 7.3 15.7 18.1 22.6 202.1 10.7 17.6 9.5 14.7 8.4 70.0 73.7 61.7 87.0 72.2 72.0 76.1 69.2 73.6 67.8 72.9 77.8 9.6 9.6 14.2 27.4 20.2 18.6 11.4 12.6 5.2 20.8 15.0 14.6 8.0 5.7 12.6 23.9 31.3 11.5 30.2 28.5 7.9 14.1 39.2 12.7 21.5 11.6 23.5 10.3 51.2 19.2 17.3 13.3 12.2 32.8 2.5 34.6 9.3 16.7 23.4 21.9 55.4 20.6 10.2 27.9 15.8 44.8 10.8 22.6 7.2 43.1 28.6 8.3 23.7 59.3 90.3 23.4 13.5 8.6 16.5 22.4 13.3 7.1 10.3 28.1 6.6 13.5 12.2 31.6 26.5 18.0 21.3 8.3 27.0 9.5 21.2 15.4 XXYLT1 "C3orf21, FLJ35155" ENSG00000173950 "Xyloside xylosyltransferase 1" Q8NBI6 3 195068284-195271159 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 110000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.39e-2)" "unprognostic (2.31e-2)" "unprognostic (3.42e-2)" "unprognostic (2.32e-3)" "unprognostic (9.57e-2)" "unprognostic (2.34e-1)" "unprognostic (6.29e-3)" "unprognostic (5.67e-2)" "unprognostic (5.50e-2)" "unprognostic (6.57e-2)" "unprognostic (3.13e-2)" "unprognostic (4.13e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.07e-1)" "unprognostic (2.23e-2)" "unprognostic (8.20e-2)" "unprognostic (1.07e-2)" 6.8 4.4 5.3 6.9 4.9 5.8 5.5 4.4 5.7 8.3 5.5 6.2 4.4 9.2 3.7 11.3 5.8 5.4 4.4 4.5 6.5 5.1 1.9 5.1 6.2 6.2 4.7 4.3 2.9 5.8 5.8 10.4 6.3 5.3 4.7 2.7 4.6 5.5 1.9 9.2 4.4 8.6 4.2 5.3 4.2 2.5 6.6 5.2 4.4 1.7 5.0 6.2 8.1 4.7 16.1 13.5 39.7 65.2 22.1 19.2 14.1 24.9 17.0 24.1 20.8 14.3 11.0 18.9 26.1 19.7 18.5 18.8 16.8 14.7 12.7 10.7 26.6 18.9 10.7 15.5 10.2 23.9 29.2 13.8 19.0 8.6 9.4 13.4 51.3 12.4 23.5 5.4 8.3 40.0 16.0 30.6 30.7 15.1 23.5 27.0 16.2 20.5 17.8 5.3 36.4 33.6 15.5 12.1 15.5 21.0 36.6 13.2 34.2 14.0 3.5 13.7 25.8 4.6 14.8 45.9 9.1 30.4 15.2 0.9 3.8 1.8 1.5 2.6 1.2 1.4 1.3 1.4 2.6 2.2 1.3 1.3 1.2 1.5 2.3 10.0 0.7 1.2 5.3 4.9 4.4 5.7 4.5 6.5 6.2 4.7 6.3 4.2 6.6 4.7 11.8 3.2 4.4 15.0 4.0 4.2 4.8 5.6 4.0 6.8 4.1 6.2 3.9 2.8 5.8 7.3 4.2 10.9 7.8 2.2 3.9 10.3 0.3 4.2 11.6 10.8 8.4 9.7 25.1 5.3 13.9 11.9 3.1 4.5 2.5 15.9 11.7 1.6 8.3 0.0 30.9 4.0 8.2 13.8 3.2 1.9 6.5 11.8 0.0 26.2 9.9 4.4 10.3 20.6 17.4 8.4 0.5 10.5 2.6 6.6 1.4 5.3 4.8 3.2 6.6 5.0 8.6 1.0 6.1 13.0 7.1 4.8 4.4 10.3 4.3 4.9 XYLT1 "PXYLT1, XT-I" ENSG00000103489 "Xylosyltransferase 1" Q86Y38 16 17101769-17470960 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 4 "monocytes: 2.0" "Cell line enhanced" "Detected in many" "ASC diff: 55.1;ASC TERT1: 34.0;U-2197: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007478, HPA007966" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA 150000 "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "Endoplasmic reticulum" "HPA007478: AB_1080616, HPA007966: AB_1080618" "unprognostic (1.82e-1)" "unprognostic (7.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (9.12e-2)" "unprognostic (8.13e-2)" "unprognostic (9.40e-2)" "unprognostic (2.41e-3)" "unprognostic (2.82e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" 6.4 6.2 6.2 4.9 8.0 7.2 4.5 2.3 6.3 7.8 8.5 8.8 4.3 7.9 1.0 5.1 3.7 2.3 4.2 8.8 3.6 1.0 0.3 3.5 5.1 3.7 4.3 5.3 2.8 0.9 0.6 6.0 4.2 2.7 5.2 8.3 2.5 4.5 1.1 5.0 5.3 5.7 1.6 5.4 3.4 2.3 3.6 4.1 2.2 1.2 4.3 4.3 4.6 4.6 0.0 0.3 8.0 0.1 55.1 34.0 9.6 25.6 12.9 2.7 1.0 0.3 0.6 6.1 0.0 31.3 0.9 0.6 0.0 5.1 4.5 12.1 0.6 8.0 0.0 0.0 0.6 11.5 10.2 12.6 0.7 15.0 2.4 4.6 0.0 0.3 0.0 23.8 2.8 0.8 0.1 12.4 8.5 4.4 0.0 3.5 0.0 1.2 0.0 11.5 2.0 15.2 1.9 7.9 1.4 5.9 1.9 7.2 0.0 24.6 2.9 57.2 0.0 26.4 1.4 11.6 28.9 12.8 22.4 0.3 0.2 0.4 0.2 1.2 0.3 0.1 0.1 0.1 0.4 0.3 0.2 0.1 0.1 0.4 2.0 0.1 0.3 0.2 6.2 8.0 2.3 6.3 8.8 3.6 3.7 4.3 4.2 1.6 3.6 4.6 1.0 3.2 2.5 45.4 9.2 7.9 1.6 0.0 1.2 12.9 3.8 3.7 3.4 0.0 0.7 0.0 98.0 12.7 12.4 9.1 0.0 1.5 0.5 0.5 24.7 2.9 12.6 7.4 172.8 1.6 20.1 12.2 2.6 0.8 2.5 6.4 1.4 0.2 3.5 0.0 72.8 4.3 4.1 9.7 27.6 0.8 12.8 8.5 3.6 29.0 6.1 1.9 11.3 1194.8 63.0 4.0 7.4 50.0 6.2 5.3 6.1 0.2 0.0 4.4 6.6 7.9 5.9 0.3 1.6 4.1 18.5 13.1 7.7 8.1 6.9 6.4 XYLT2 "PXYLT2, XT-II" ENSG00000015532 "Xylosyltransferase 2" Q9H1B5 17 50346126-50363138 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "stomach 1: 86.7" "Group enriched" "Detected in many" 6 "Early spermatids: 316.4;Late spermatids: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 1100000 "Cluster 39: Non-specific - mRNA processing" "Cluster 4: Stomach - Digestion" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (1.52e-1)" "unprognostic (2.84e-1)" "unprognostic (1.65e-1)" "unprognostic (8.07e-2)" "unprognostic (1.90e-3)" "unprognostic (1.90e-1)" "unprognostic (7.29e-3)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (2.30e-1)" "unprognostic (1.54e-2)" "unprognostic (2.81e-1)" "unprognostic (7.63e-2)" "unprognostic (5.15e-2)" "unprognostic (7.38e-2)" "unprognostic (1.52e-2)" "unprognostic (2.68e-2)" 7.4 9.7 4.9 6.6 5.2 4.5 8.1 8.0 8.2 12.3 8.7 10.0 9.6 11.4 5.3 8.4 11.8 6.6 9.1 5.6 3.0 8.9 7.5 7.3 9.3 4.1 5.6 13.6 12.9 9.4 6.4 8.6 3.8 13.6 3.6 4.5 12.2 10.1 5.8 15.3 8.7 5.2 2.5 10.1 86.7 6.7 7.0 8.6 9.3 2.4 4.0 12.0 10.9 5.3 21.1 26.2 7.0 5.9 9.7 9.4 18.4 19.3 17.4 17.2 19.1 28.3 15.5 10.9 47.6 17.3 14.9 15.8 2.4 27.0 3.7 54.3 18.5 24.6 8.6 12.4 13.3 7.8 12.5 12.8 16.4 13.6 6.3 16.9 14.9 9.4 4.4 8.8 11.3 27.5 14.4 10.7 6.5 14.0 18.0 7.2 20.4 9.0 9.5 10.8 3.6 9.0 12.9 11.9 20.3 8.0 57.4 7.5 17.4 38.4 19.2 20.9 17.3 48.0 23.6 3.9 40.4 12.3 10.6 3.7 2.0 1.5 2.7 1.2 2.7 1.3 2.7 3.6 2.4 2.2 2.7 2.5 1.9 3.6 1.1 1.6 2.5 2.9 4.9 5.2 8.0 8.2 5.6 3.0 4.1 5.6 3.8 2.5 7.0 5.3 7.5 9.6 6.1 13.1 3.9 5.7 3.2 7.3 5.7 8.3 3.9 5.7 8.4 10.0 4.4 1.8 29.2 7.0 3.8 7.5 0.0 7.1 316.4 4.6 6.7 6.8 10.8 0.8 4.9 6.2 5.4 9.1 17.3 6.8 1.3 9.6 10.4 8.0 3.6 6.7 7.2 9.4 2.0 6.0 1.4 91.4 12.5 3.8 7.2 6.5 2.7 5.9 5.2 6.6 4.7 6.8 3.5 17.3 4.7 2.0 4.6 2.8 3.2 6.1 26.3 6.9 6.7 2.4 4.3 3.4 3.1 1.5 4.8 5.3 11.1 1.4 YBX3 "CSDA, CSDA1, dbpA, ZONAB" ENSG00000060138 "Y-box binding protein 3" P16989 12 10699089-10723323 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 4915.7;tongue: 1635.6" "Cell type enhanced" "Detected in many" "Early spermatids: 1418.1;Prostatic glandular cells: 1553.4;Skeletal myocytes: 1316.7;Urothelial cells: 1339.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 6.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034838 Approved Supported Cytosol NA NA 230000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA034838: AB_10670980" "unprognostic (1.93e-2)" "unprognostic (6.20e-2)" "unprognostic (3.56e-1)" "unprognostic (3.61e-2)" "unprognostic (4.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.10e-1)" "unprognostic (3.81e-2)" "unprognostic (2.91e-1)" "unprognostic (2.41e-1)" "unprognostic (3.23e-3)" "unprognostic (1.20e-1)" "prognostic unfavorable (6.17e-13)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.44e-1)" 250.4 96.7 17.6 77.5 17.6 151.1 200.2 18.8 25.5 152.1 28.4 249.1 37.5 136.8 47.3 271.0 166.7 65.0 469.9 16.5 22.3 194.1 53.8 209.5 32.9 25.4 22.4 134.6 291.0 18.6 84.1 72.5 23.9 177.1 58.8 82.8 218.1 67.5 4915.7 358.1 99.0 100.9 20.9 79.5 149.7 265.7 22.2 36.7 136.1 1635.6 54.6 225.4 204.8 19.7 117.2 90.3 41.4 136.1 165.7 310.7 307.4 173.4 142.7 138.7 132.0 160.4 259.5 109.3 57.7 130.3 96.5 215.5 173.3 338.1 124.6 1.2 325.2 91.3 123.6 108.4 198.3 171.7 10.4 343.3 452.3 124.2 414.6 148.9 313.6 152.3 123.1 0.4 154.7 112.6 137.8 141.9 435.5 103.7 76.9 76.9 192.6 127.4 192.6 150.0 52.2 0.3 129.1 130.9 174.1 288.0 37.1 133.9 221.3 94.5 282.6 108.4 201.5 0.5 38.1 13.4 133.1 0.2 104.8 0.0 4.2 0.0 0.6 4.2 0.0 1.6 0.0 1.5 3.2 6.5 0.0 1.6 0.8 0.8 2.4 0.1 0.1 1.0 17.6 17.6 18.8 25.5 16.5 22.3 25.4 22.4 23.9 20.9 22.2 19.7 680.9 150.6 164.4 14.0 192.8 764.9 1226.9 212.9 552.7 36.1 288.8 292.7 497.7 105.8 177.8 145.3 89.6 145.7 39.2 94.3 133.1 125.3 1418.1 563.0 402.1 563.1 67.6 1081.5 2.4 143.3 84.3 484.8 119.8 551.3 63.3 291.0 235.6 23.1 97.7 16.8 1.0 139.5 120.1 223.2 494.7 470.2 264.7 292.2 259.7 21.5 83.9 67.2 2.1 4.5 0.1 122.0 76.3 223.8 80.6 1553.4 43.9 240.4 240.4 365.4 124.9 1316.7 643.1 594.6 158.4 638.6 1050.5 125.7 72.5 70.8 157.4 1339.7 YEATS2 "FLJ10201, FLJ12841, FLJ13308, KIAA1197" ENSG00000163872 "YEATS domain containing 2" Q9ULM3 3 183697797-183812624 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 95.6;Inhibitory neurons: 62.1;Oligodendrocyte precursor cells: 71.9;Oligodendrocytes: 80.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045891 Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA045891: AB_10961271" "unprognostic (1.57e-2)" "unprognostic (1.10e-1)" "unprognostic (3.56e-2)" "unprognostic (3.40e-3)" "unprognostic (1.14e-1)" "unprognostic (7.49e-2)" "prognostic unfavorable (4.82e-6)" "unprognostic (2.44e-1)" "unprognostic (3.91e-2)" "unprognostic (1.32e-1)" "unprognostic (8.33e-3)" "unprognostic (1.65e-3)" "prognostic unfavorable (6.90e-9)" "unprognostic (1.66e-1)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (2.08e-2)" 7.4 4.8 5.4 8.9 7.4 14.5 7.9 8.1 8.8 8.5 0.0 9.1 5.4 9.0 4.7 8.2 10.3 6.5 6.6 6.4 5.2 6.1 3.4 10.0 12.9 2.4 3.7 15.1 5.4 9.9 8.6 11.2 3.0 8.2 6.8 15.6 8.0 7.3 5.5 8.5 7.0 11.9 1.9 8.9 5.8 8.0 4.2 16.9 9.7 4.8 11.8 8.7 8.4 7.0 38.1 11.3 32.4 14.5 15.5 22.8 35.8 22.1 17.0 32.1 37.5 27.8 13.3 34.7 39.8 19.5 49.9 23.9 31.8 21.2 32.7 28.5 18.8 35.0 12.2 13.7 23.9 26.3 19.4 15.6 16.3 23.1 27.8 32.1 33.1 35.2 14.0 28.3 24.5 10.2 38.3 20.2 29.3 13.8 22.0 53.5 30.5 42.0 12.9 16.6 31.3 22.3 16.4 55.4 29.2 27.1 27.5 17.8 28.2 29.5 21.3 15.1 25.0 26.9 22.6 57.6 22.9 25.8 21.3 0.1 4.6 1.2 1.9 2.0 1.3 1.9 1.7 1.4 1.6 1.3 1.3 1.5 8.5 1.3 7.1 2.1 0.7 1.8 5.4 7.4 8.1 8.8 6.4 5.2 2.4 3.7 3.0 1.9 4.2 7.0 13.8 35.3 2.3 41.4 7.0 2.0 3.3 7.0 8.6 19.5 5.6 7.5 10.1 5.7 5.9 5.5 10.4 4.8 7.4 4.4 0.0 5.7 2.4 10.5 18.3 15.3 8.5 6.3 95.6 4.0 9.7 9.2 7.1 9.8 7.0 42.1 7.5 3.0 7.1 13.5 62.1 6.0 6.1 8.7 6.7 3.3 9.9 10.1 1.8 40.3 6.6 5.8 5.2 71.9 80.0 7.1 3.1 9.4 9.5 5.3 4.7 1.0 11.2 15.8 0.0 10.1 10.4 3.1 12.3 8.7 3.4 2.1 8.8 9.7 4.8 2.8 YIPF4 "FinGER4, MGC11061" ENSG00000119820 "Yip1 domain family member 4" Q9BSR8 2 32277904-32316594 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 129.1;choroid plexus: 65.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017884 Supported Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "Vesicles, Plasma membrane" "HPA017884: AB_1853855" "unprognostic (5.61e-3)" "unprognostic (8.50e-2)" "unprognostic (3.88e-2)" "unprognostic (3.17e-3)" "unprognostic (3.05e-1)" "unprognostic (7.64e-2)" "unprognostic (3.45e-2)" "unprognostic (3.61e-2)" "unprognostic (3.69e-1)" "unprognostic (8.70e-2)" "unprognostic (4.15e-1)" "unprognostic (1.54e-1)" "unprognostic (2.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (6.11e-2)" 7.0 6.2 69.9 5.5 66.9 2.5 8.4 69.6 129.1 6.1 65.6 6.9 5.8 6.9 7.2 5.0 5.0 4.5 7.4 71.7 68.8 7.7 9.2 5.6 5.9 69.3 67.7 6.6 14.8 6.5 5.2 5.9 71.9 6.6 6.2 13.1 7.4 5.6 8.0 7.0 5.8 6.5 66.8 6.9 6.4 4.2 67.3 7.9 10.1 6.0 5.1 5.3 5.1 75.4 8.9 4.4 8.6 7.7 9.8 12.4 4.5 7.5 7.5 7.7 5.0 5.9 6.6 4.7 5.1 8.2 7.4 6.8 9.2 6.6 10.0 7.6 14.3 7.6 9.8 10.7 11.5 10.2 6.2 8.7 12.4 6.9 11.0 10.6 6.6 5.2 10.7 9.6 8.5 5.8 8.0 10.6 7.0 9.6 7.5 5.5 12.7 8.9 8.4 3.8 9.6 9.2 6.4 6.4 11.7 5.5 3.5 8.6 7.4 10.1 4.8 7.1 7.2 14.2 19.1 5.8 15.9 9.7 5.7 14.9 5.4 5.7 4.4 5.1 3.7 4.6 4.4 4.1 4.6 4.0 4.5 4.0 14.9 6.4 5.1 5.4 4.6 4.7 69.9 66.9 69.6 129.1 71.7 68.8 69.3 67.7 71.9 66.8 67.3 75.4 61.4 93.0 69.8 13.1 68.5 51.4 56.9 59.5 50.7 113.8 63.3 28.2 88.0 60.1 58.3 42.3 106.3 68.4 81.3 68.8 33.2 45.3 34.7 39.5 57.9 59.0 57.1 86.9 18.8 39.3 69.9 66.6 28.1 40.1 40.0 56.3 67.8 80.9 48.3 101.0 20.1 70.2 50.8 81.7 60.7 21.0 86.6 58.0 81.8 21.5 85.1 53.1 114.4 22.1 31.8 41.8 66.8 74.9 62.6 78.5 62.7 60.1 62.2 122.2 78.9 71.9 66.2 160.2 59.6 41.1 65.9 192.8 60.7 65.4 46.8 74.7 YY1AP1 "HCCA2, YAP, YY1AP" ENSG00000163374 "YY1 associated protein 1" Q9H869 1 155659443-155689000 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA006986, HPA064249" Uncertain Approved "Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Nucleoli fibrillar center" "HPA006986: AB_1080620, HPA064249: AB_2685226" "unprognostic (1.96e-2)" "unprognostic (2.80e-1)" "unprognostic (1.09e-2)" "unprognostic (5.67e-2)" "unprognostic (3.91e-2)" "unprognostic (1.77e-1)" "unprognostic (2.86e-3)" "unprognostic (1.23e-1)" "unprognostic (6.95e-2)" "unprognostic (8.13e-2)" "unprognostic (6.87e-2)" "unprognostic (8.65e-2)" "prognostic unfavorable (2.01e-6)" "unprognostic (6.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.39e-1)" "unprognostic (5.84e-2)" 41.9 36.1 35.4 28.1 38.6 77.2 42.8 51.1 41.6 47.1 20.7 56.6 23.5 41.5 38.6 53.0 44.2 26.7 48.1 33.5 32.7 42.3 38.3 49.3 38.6 32.6 35.2 47.5 37.6 35.4 47.1 32.0 32.4 46.3 35.6 41.3 41.0 37.6 113.8 54.0 39.7 42.6 31.7 47.9 41.8 74.6 38.8 50.4 39.9 73.2 49.8 45.8 45.8 41.3 63.5 32.0 40.3 45.9 44.9 40.4 86.5 39.9 58.0 70.4 59.9 49.3 65.7 50.1 38.4 58.6 35.8 60.5 61.3 55.7 66.2 46.7 30.5 41.6 36.2 31.2 47.5 66.7 54.2 43.0 56.1 53.7 68.5 48.8 44.3 47.5 55.8 69.9 52.2 56.0 68.5 32.4 63.7 86.5 46.4 53.7 34.9 80.4 42.7 45.5 40.3 47.8 52.6 75.0 51.5 72.5 82.3 108.7 36.0 39.4 34.6 41.4 53.5 87.7 62.8 123.2 38.9 43.0 46.4 40.3 27.6 50.3 34.7 27.5 36.8 26.7 29.6 36.4 34.0 20.9 25.5 25.5 29.5 45.0 27.7 15.9 40.1 35.1 35.4 38.6 51.1 41.6 33.5 32.7 32.6 35.2 32.4 31.7 38.8 41.3 18.3 19.2 26.7 28.7 26.0 34.7 30.5 20.2 38.7 24.5 27.4 21.3 23.2 22.8 22.9 12.9 43.8 23.6 24.5 25.7 13.7 17.3 68.0 20.0 21.8 24.5 34.9 42.9 33.8 19.1 27.9 24.7 25.0 25.5 25.3 16.6 15.7 23.1 21.5 16.8 34.8 23.8 12.2 20.8 36.3 81.0 28.0 28.5 19.6 37.5 27.4 20.8 15.5 38.7 48.3 18.4 16.2 25.6 36.9 29.2 22.5 11.7 17.3 24.9 6.6 24.9 22.3 77.6 25.5 38.8 35.7 45.0 26.7 26.6 24.4 33.8 Z83844.2 ENSG00000285304 "Novel protein" 22 37639693-37666932 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 33.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA000757 Approved Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: HMC-1 - Innate immune response" Cytosol "HPA000757: AB_1079951" 1.0 0.2 0.1 7.3 0.0 8.8 1.0 0.1 1.4 3.1 0.0 5.9 5.6 1.3 0.0 4.0 1.6 1.3 0.5 0.2 0.1 0.0 0.9 3.4 7.4 0.0 0.0 1.0 0.7 2.6 3.7 0.2 0.9 5.0 0.1 2.1 2.3 0.2 1.7 8.1 2.3 0.1 3.9 1.4 0.7 0.2 6.5 0.5 0.0 6.6 4.2 0.4 14.7 2.1 7.7 5.0 2.3 6.5 8.3 4.1 12.9 15.3 15.8 9.8 3.5 8.4 1.4 4.5 5.1 12.2 9.2 22.3 4.7 10.2 7.0 21.3 0.0 10.7 4.2 33.2 25.5 7.8 9.4 17.7 1.6 6.5 0.9 6.1 5.9 7.5 0.7 13.4 1.2 1.9 7.9 23.9 1.6 12.6 4.9 7.7 1.6 4.5 4.4 7.2 1.1 4.9 8.0 5.4 6.4 14.5 1.5 2.0 7.5 1.2 0.0 12.3 4.7 8.8 5.2 21.5 14.8 0.0 0.6 0.0 0.4 0.3 0.3 0.3 0.2 0.5 0.9 0.2 0.6 0.4 0.0 0.5 0.6 0.4 0.6 0.3 0.1 0.0 0.1 1.4 0.2 0.1 0.0 0.0 0.2 0.1 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 Z84492.1 ENSG00000272104 "Novel protein" 3 50350892-50367923 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 4.8;Karpas-707: 6.5" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "unprognostic (2.51e-1)" "unprognostic (9.06e-2)" 1.7 0.5 2.4 0.9 2.2 1.1 1.7 1.9 3.7 1.5 1.0 2.8 4.6 0.8 4.0 1.2 1.6 0.8 0.3 1.5 3.2 2.5 0.4 0.5 4.5 1.8 1.6 3.0 3.5 1.2 0.7 0.2 1.7 2.7 1.1 0.4 4.3 1.0 0.6 4.4 4.7 0.5 1.4 2.6 3.6 1.3 2.4 1.2 3.2 0.1 1.8 0.6 0.0 1.7 1.6 0.0 0.0 1.0 1.1 0.0 0.3 1.7 1.1 0.3 1.3 0.0 1.0 0.9 1.5 0.0 0.1 0.9 0.0 0.6 0.9 1.8 0.4 0.0 1.3 0.0 0.4 0.0 4.8 0.0 0.8 0.6 0.0 0.2 0.0 2.4 0.3 6.5 0.0 0.6 1.8 0.0 0.6 1.6 0.0 0.6 0.3 2.6 0.3 0.0 1.2 3.0 0.0 1.2 0.2 0.3 1.1 0.0 0.0 0.3 0.1 0.0 0.5 1.6 2.5 1.1 0.0 0.4 0.0 4.8 0.1 3.6 5.8 0.3 8.4 8.3 10.5 8.6 0.1 9.3 14.2 8.2 0.5 10.4 0.7 1.6 15.4 3.0 2.4 2.2 1.9 3.7 1.5 3.2 1.8 1.6 1.7 1.4 2.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZBTB10 "FLJ12752, RINZF" ENSG00000205189 "Zinc finger and BTB domain containing 10" Q96DT7 8 80485619-80526265 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 142.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 48.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021554, HPA050569" Enhanced Enhanced Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA021554: AB_1858937, HPA050569: AB_2681179" "unprognostic (7.97e-2)" "unprognostic (3.53e-1)" "unprognostic (2.26e-1)" "unprognostic (6.67e-2)" "unprognostic (9.28e-2)" "unprognostic (8.97e-3)" "unprognostic (1.29e-2)" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (4.86e-1)" "unprognostic (3.66e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.52e-4)" "unprognostic (4.65e-3)" "unprognostic (2.40e-1)" "unprognostic (7.15e-2)" "unprognostic (2.63e-2)" 7.9 7.9 4.1 4.8 5.2 23.7 8.2 12.1 4.4 8.7 3.9 6.9 2.0 11.2 6.1 3.7 11.8 7.4 7.5 3.3 5.1 10.2 18.5 6.2 5.3 4.9 4.4 12.7 14.0 7.1 3.5 17.8 5.0 14.1 7.8 7.3 7.6 6.3 5.4 1.9 2.2 8.9 4.3 7.0 4.6 11.2 4.7 8.6 10.1 8.0 3.4 5.5 3.3 5.7 0.0 4.2 21.1 10.7 9.1 6.9 28.5 3.9 0.0 3.0 3.0 9.2 3.4 12.7 11.0 5.8 9.2 0.9 16.7 5.3 3.5 0.0 26.8 6.5 2.8 7.3 5.3 2.2 2.9 6.5 4.6 3.7 10.6 2.5 7.7 10.5 5.9 24.2 2.5 6.7 12.6 5.5 5.3 1.3 6.6 14.7 11.1 4.5 8.4 12.5 12.6 14.6 5.2 48.5 14.8 23.6 9.4 9.1 9.9 7.3 13.5 0.1 3.6 7.0 3.7 14.0 2.8 0.0 9.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.2 0.1 0.4 0.3 0.3 0.0 0.5 0.2 0.9 0.0 0.0 4.1 5.2 12.1 4.4 3.3 5.1 4.9 4.4 5.0 4.3 4.7 5.7 37.1 25.6 17.0 18.9 55.3 28.4 21.1 8.1 44.3 13.4 48.8 39.8 36.1 25.8 11.8 12.9 16.7 38.3 34.1 38.9 3.9 13.1 83.7 82.4 60.6 34.5 60.4 3.0 12.8 6.9 41.0 29.3 40.8 142.6 9.5 37.0 16.8 31.7 13.3 32.0 11.1 43.0 20.3 21.3 79.6 29.7 19.3 32.0 49.8 13.1 11.2 20.8 8.2 19.6 13.4 8.3 14.8 21.1 24.5 82.1 0.4 14.5 19.4 10.6 26.3 46.6 49.5 14.6 10.6 13.6 12.6 105.2 28.4 19.6 34.7 19.6 ZBTB22 "BING1, fru, fruitless, ZBTB22A, ZNF297, ZNF297A" ENSG00000236104 "Zinc finger and BTB domain containing 22" O15209 6 33314406-33317942 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043848 Approved Nucleoplasm No No "Cluster 2: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA043848: AB_10961146" "unprognostic (1.32e-1)" "unprognostic (2.87e-1)" "unprognostic (3.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.38e-1)" "unprognostic (2.82e-1)" "unprognostic (1.31e-1)" "unprognostic (1.55e-2)" "unprognostic (2.06e-1)" "unprognostic (6.88e-2)" "unprognostic (4.98e-2)" "unprognostic (1.81e-1)" "unprognostic (6.54e-3)" "unprognostic (1.67e-2)" "unprognostic (2.86e-1)" "unprognostic (1.66e-2)" "unprognostic (9.32e-3)" 10.2 15.1 1.2 2.6 1.2 2.1 11.3 1.1 3.5 15.6 0.7 10.4 4.7 15.6 8.5 13.3 12.6 1.7 10.6 1.2 0.9 11.9 10.1 12.0 1.1 2.1 1.3 14.9 12.2 11.6 10.5 2.3 1.4 12.1 4.2 5.7 12.0 3.8 8.6 19.2 11.6 3.0 1.5 13.7 11.8 6.1 1.0 5.3 15.1 3.9 3.9 12.0 13.2 1.4 0.3 0.3 8.5 4.4 8.3 3.3 3.5 7.5 7.3 7.1 4.6 0.1 1.9 1.9 5.6 12.5 9.1 0.6 0.3 4.6 5.2 11.7 2.8 7.5 4.4 4.1 0.0 0.0 2.8 10.8 10.0 0.3 2.6 9.8 0.7 6.3 2.9 7.8 2.6 4.7 4.6 6.7 0.0 0.4 2.2 0.5 0.1 4.2 6.3 0.4 9.7 0.6 0.7 0.4 4.3 5.0 0.7 0.4 10.7 3.9 4.5 0.2 0.2 4.3 4.5 1.9 5.6 1.1 4.3 0.8 0.2 0.8 0.3 0.3 0.1 0.5 0.4 0.2 0.2 0.3 0.7 0.1 0.3 0.1 0.2 0.4 0.1 0.2 1.2 1.2 1.1 3.5 1.2 0.9 2.1 1.3 1.4 1.5 1.0 1.4 9.4 0.0 5.0 2.6 7.3 6.4 16.3 6.0 8.6 20.1 9.9 7.6 4.3 4.3 4.9 7.3 8.4 6.3 3.3 9.8 23.5 11.0 1.6 8.3 5.2 7.7 7.7 4.0 2.8 7.1 4.6 6.7 5.6 6.9 3.8 6.5 7.9 2.0 5.3 20.2 2.8 8.7 12.2 4.4 4.0 1.8 9.3 5.3 1.8 3.7 12.1 18.2 8.2 3.5 2.6 6.5 8.6 6.4 4.0 10.9 7.6 8.3 6.0 21.2 13.1 10.0 7.6 2.2 2.0 8.1 7.4 10.1 4.9 8.0 5.8 11.8 ZBTB9 "MGC23166, ZNF919" ENSG00000213588 "Zinc finger and BTB domain containing 9" Q96C00 6 33453970-33457544 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.5;Ionocytes: 6.1;Respiratory ciliated cells: 4.3;Suprabasal keratinocytes: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 11.6;BEWO: 11.3;GAMG: 16.5;HMC-1: 14.2;U-698: 12.0" "Low region specificity" "Detected in all" "HPA036767, HPA058171" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Nuclear membrane, Cytosol" "HPA036767: AB_10696787, HPA058171: " "unprognostic (1.79e-2)" "unprognostic (1.46e-1)" "unprognostic (6.86e-2)" "unprognostic (2.89e-1)" "unprognostic (2.18e-1)" "unprognostic (9.16e-2)" "unprognostic (1.85e-4)" "unprognostic (4.20e-1)" "unprognostic (2.73e-1)" "unprognostic (2.13e-1)" "unprognostic (1.70e-2)" "unprognostic (4.10e-1)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (2.47e-1)" "unprognostic (2.95e-1)" 2.8 3.9 0.9 1.5 1.0 1.7 2.3 0.8 1.6 2.5 8.6 2.4 2.3 2.6 1.7 3.8 2.5 0.6 3.0 1.9 0.7 4.4 3.2 2.4 1.9 1.2 0.9 3.0 2.9 0.6 10.0 0.5 0.6 2.4 1.4 1.9 2.9 0.1 1.8 3.8 2.7 0.8 0.2 3.5 2.7 7.4 0.4 0.2 2.2 1.0 3.3 2.5 2.2 0.9 1.0 0.3 11.6 2.9 2.1 0.1 11.3 0.6 0.2 0.2 0.1 3.0 0.8 2.7 1.8 0.3 16.5 1.2 4.8 2.4 1.3 3.1 2.0 9.0 2.3 0.0 0.0 2.3 14.2 0.5 0.9 3.3 2.6 0.6 0.1 1.5 3.2 1.8 2.6 1.6 0.6 0.9 4.3 0.5 0.7 5.6 3.0 2.7 2.2 2.3 1.8 1.1 3.3 0.3 1.1 1.1 1.6 0.4 1.9 0.9 1.3 1.3 1.2 0.7 3.5 12.0 0.9 2.9 0.3 5.2 1.1 0.4 2.8 0.8 1.2 0.4 1.2 2.6 1.5 0.8 2.5 1.9 0.8 1.3 1.7 0.3 2.2 0.6 0.9 1.0 0.8 1.6 1.9 0.7 1.2 0.9 0.6 0.2 0.4 0.9 0.1 0.0 0.0 1.3 2.1 4.5 0.0 1.9 1.8 0.0 0.2 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.5 0.0 1.5 0.3 0.4 0.1 0.6 1.8 1.3 1.2 1.3 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.7 6.1 0.0 1.2 1.1 0.0 0.2 1.8 1.0 0.0 0.0 0.0 0.0 0.6 1.0 0.1 0.0 0.6 0.0 0.2 0.1 4.3 0.0 0.0 0.0 0.7 0.1 0.1 0.8 3.7 0.0 0.7 0.1 1.0 0.0 ZDHHC22 C14orf59 ENSG00000177108 "Zinc finger DHHC-type palmitoyltransferase 22" Q8N966 14 77131270-77142734 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 51.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.3;Excitatory neurons: 8.8;Inhibitory neurons: 13.4;Late spermatids: 5.0;Oligodendrocyte precursor cells: 24.6" "Cancer enriched" "Detected in single" 40 "glioma: 7.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 3.6;NTERA-2: 3.8;RH-30: 6.4;SCLC-21H: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049471, HPA072213" Enhanced "Plasma membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA049471: AB_2732553, HPA072213: AB_2686496" "unprognostic (1.02e-1)" "unprognostic (3.42e-1)" "unprognostic (1.22e-4)" "unprognostic (1.66e-1)" "unprognostic (8.86e-2)" "unprognostic (2.68e-1)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "unprognostic (6.94e-4)" "unprognostic (3.05e-1)" "unprognostic (6.30e-2)" "unprognostic (1.16e-1)" "unprognostic (4.02e-1)" "unprognostic (1.95e-1)" "unprognostic (4.79e-1)" 0.0 0.2 14.9 0.0 15.3 0.0 0.0 25.9 33.8 0.1 0.0 0.7 0.0 0.0 0.2 0.1 0.0 0.0 0.0 21.2 12.8 0.0 0.0 0.0 0.0 1.2 22.7 0.0 0.0 0.0 4.7 0.0 1.0 0.0 0.1 7.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.5 51.3 0.0 0.1 0.4 0.0 0.1 0.0 13.9 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 3.8 0.0 0.5 0.0 6.4 0.0 0.0 0.0 7.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 15.3 25.9 33.8 21.2 12.8 1.2 22.7 1.0 0.0 51.3 13.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.3 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 24.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZFAND6 "AWP1, ZA20D3, ZFAND5B" ENSG00000086666 "Zinc finger AN1-type containing 6" Q6FIF0 15 80059568-80138393 "Predicted intracellular proteins" "Apoptosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 496.7;Late spermatids: 598.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034845, HPA052746, HPA077824" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA034845: AB_10671234, HPA052746: , HPA077824: " "unprognostic (2.04e-1)" "unprognostic (2.25e-2)" "unprognostic (3.26e-1)" "unprognostic (2.31e-1)" "unprognostic (1.29e-1)" "unprognostic (3.70e-2)" "unprognostic (4.26e-2)" "unprognostic (1.03e-1)" "unprognostic (4.91e-2)" "unprognostic (1.22e-1)" "unprognostic (1.74e-2)" "unprognostic (6.48e-3)" "unprognostic (4.90e-3)" "unprognostic (1.22e-1)" "unprognostic (1.45e-1)" "unprognostic (1.55e-1)" "prognostic favorable (8.20e-4)" 63.2 70.2 41.3 48.4 43.1 79.9 65.4 54.5 48.8 47.8 48.7 61.5 54.8 58.2 66.2 54.9 54.9 49.8 90.5 42.1 50.1 76.3 123.5 55.7 73.2 50.6 46.4 40.8 42.1 60.6 41.2 50.6 47.7 56.3 61.1 74.2 52.9 50.6 128.5 44.0 53.9 59.8 53.7 60.9 59.6 135.9 44.0 50.9 100.9 109.8 75.5 55.2 43.1 57.2 78.9 161.0 116.9 67.3 118.0 93.4 110.3 91.7 127.2 78.7 107.0 56.6 133.6 87.5 115.7 94.3 76.6 63.1 125.9 92.3 83.8 52.8 107.2 207.1 72.7 78.5 138.2 74.7 131.9 83.3 117.8 87.3 117.7 108.3 120.0 74.4 84.5 66.8 87.3 83.3 59.5 74.0 73.6 70.3 53.4 48.1 102.6 200.8 196.3 129.4 23.9 68.8 79.2 91.0 238.4 144.5 89.1 106.7 111.5 82.1 66.5 53.2 89.8 88.9 189.1 102.6 85.0 127.1 58.6 505.1 90.0 290.1 93.6 118.9 82.5 226.4 84.7 91.2 103.1 174.4 88.2 98.4 216.3 85.0 167.1 89.5 91.2 135.7 41.3 43.1 54.5 48.8 42.1 50.1 50.6 46.4 47.7 53.7 44.0 57.2 60.5 54.5 86.8 76.0 122.5 149.5 141.3 236.1 46.7 40.3 96.2 60.1 92.7 85.8 147.8 75.4 41.7 125.3 101.1 95.9 199.6 103.7 496.7 102.0 57.0 75.0 82.6 97.2 18.1 98.3 130.8 75.0 69.8 135.3 105.1 57.0 72.8 154.6 144.2 32.0 27.7 88.6 203.4 96.1 173.5 598.2 53.1 109.8 124.5 78.7 167.2 101.3 91.6 61.9 73.9 126.5 107.6 62.8 92.7 174.1 64.8 278.8 168.3 89.9 92.1 70.0 98.6 230.6 173.3 62.8 169.3 392.8 87.0 67.6 67.3 183.4 ZFP36 "G0S24, NUP475, RNF162A, TIS11, TTP" ENSG00000128016 "ZFP36 ring finger protein" P26651 19 39406847-39409412 "Predicted intracellular proteins" "Host-virus interaction, mRNA transport, RNA-mediated gene silencing, Transport" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 2759.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 313.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 154.7;hTCEpi: 179.0;Karpas-707: 167.0;U-266/84: 149.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 151.4" HPA006009 Approved Approved "Intermediate filaments" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments" "HPA006009: AB_1859030" "unprognostic (2.30e-2)" "unprognostic (2.27e-1)" "unprognostic (8.26e-2)" "unprognostic (6.76e-2)" "unprognostic (4.74e-3)" "unprognostic (1.19e-1)" "unprognostic (2.22e-1)" "unprognostic (4.59e-2)" "unprognostic (5.20e-1)" "unprognostic (3.61e-3)" "unprognostic (9.44e-2)" "unprognostic (3.11e-1)" "unprognostic (4.20e-3)" "unprognostic (5.22e-3)" "unprognostic (1.35e-1)" "unprognostic (7.05e-2)" "unprognostic (6.92e-3)" 1520.5 341.7 46.9 258.1 49.9 745.3 716.3 55.6 74.0 517.1 71.2 582.4 168.3 316.1 17.0 645.5 1276.8 520.0 575.4 42.8 84.3 288.1 462.0 1135.1 175.1 130.5 63.1 480.5 160.6 124.5 311.5 120.9 68.5 342.3 175.6 39.2 329.7 143.6 322.8 828.9 322.5 426.0 78.8 282.1 554.4 49.4 86.3 269.6 510.2 281.6 73.1 523.2 712.5 79.6 27.5 16.5 4.3 1.5 108.8 154.7 7.7 20.8 26.7 11.2 8.7 12.8 28.3 16.8 6.2 32.7 12.1 13.2 1.0 35.0 3.5 21.1 1.6 7.2 12.1 8.0 70.2 7.4 41.6 56.7 179.0 8.0 66.3 14.6 6.6 18.7 10.2 167.0 19.4 21.5 13.2 17.7 1.6 83.4 2.6 18.9 2.3 35.9 14.9 43.6 1.2 4.2 10.1 23.6 6.1 6.3 16.8 39.8 11.4 15.3 6.1 28.2 6.3 116.5 149.7 19.5 15.4 15.1 6.4 121.8 72.2 68.8 38.8 69.9 32.8 47.8 33.4 39.5 69.0 45.5 38.0 37.0 313.6 17.4 95.5 50.9 41.9 44.3 46.9 49.9 55.6 74.0 42.8 84.3 130.5 63.1 68.5 78.8 86.3 79.6 2759.0 419.9 864.0 7.5 686.2 1160.4 1543.0 789.3 2108.6 0.4 819.5 566.2 514.9 351.8 426.9 80.9 4.2 70.3 962.4 628.2 31.3 234.2 6.1 528.1 797.5 1208.6 631.9 109.2 0.4 105.6 95.5 2072.6 881.3 1055.0 690.7 45.7 668.6 206.4 703.1 1.7 0.2 608.3 250.3 669.9 2332.1 17.4 557.7 1189.0 631.5 24.4 125.6 55.0 94.7 0.0 1.6 156.4 907.8 139.5 1540.1 823.3 1060.8 60.2 298.5 7.1 769.2 878.2 1346.7 2.9 5.4 1641.6 1585.6 154.2 1193.0 87.1 366.5 639.9 ZFP36L1 "Berg36, BRF1, cMG1, ERF1, RNF162B, TIS11B" ENSG00000185650 "ZFP36 ring finger protein like 1" Q07352 14 68787660-68796253 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA transport, Transport" "Developmental protein, DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1973.2;Squamous epithelial cells: 2019.8;Suprabasal keratinocytes: 3223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 2901.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 2901.2" "Cell line enhanced" "Detected in all" "hTERT-HME1: 462.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001301 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA001301: AB_1080644" "unprognostic (1.18e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.58e-1)" "unprognostic (7.00e-2)" "unprognostic (1.27e-1)" "unprognostic (1.64e-2)" "unprognostic (1.11e-1)" "unprognostic (2.17e-2)" "unprognostic (3.81e-3)" "unprognostic (1.13e-3)" "unprognostic (1.30e-1)" "unprognostic (1.11e-2)" "unprognostic (6.45e-3)" "unprognostic (5.77e-2)" "unprognostic (2.97e-1)" "unprognostic (5.68e-2)" 342.7 107.9 108.1 218.2 108.3 84.0 305.6 118.0 96.1 466.4 91.7 335.1 127.5 423.1 107.7 293.0 303.3 174.9 178.8 98.7 184.1 157.8 260.1 242.7 199.5 207.8 187.5 453.5 225.4 161.7 67.3 315.8 145.0 222.3 104.2 57.5 319.3 201.7 93.1 511.3 151.5 316.0 162.7 178.5 196.9 49.3 142.6 130.1 190.6 89.6 150.4 335.8 467.0 166.8 235.6 211.8 94.7 139.0 234.4 187.2 203.9 96.4 169.6 59.1 72.9 93.9 159.5 58.4 59.5 177.4 85.5 108.4 8.8 313.8 70.0 27.9 13.2 21.5 115.0 68.2 133.8 3.3 24.3 157.6 396.4 69.1 462.1 195.2 119.2 17.1 61.5 113.7 314.4 54.1 9.3 11.1 78.7 105.1 31.7 150.5 127.1 17.8 213.4 155.3 1.0 2.5 113.7 163.4 87.8 131.9 148.3 3.0 254.4 167.3 122.8 139.0 101.0 62.9 32.9 39.9 213.5 1.4 66.9 230.8 240.9 3.9 211.1 244.7 197.2 266.0 168.8 150.3 123.8 461.4 179.3 162.2 2901.2 154.3 176.1 16.2 174.5 257.5 108.1 108.3 118.0 96.1 98.7 184.1 207.8 187.5 145.0 162.7 142.6 166.8 830.2 477.5 415.6 172.7 513.8 1333.5 761.2 830.2 1973.2 4.6 750.7 504.4 84.2 420.4 523.9 364.1 0.0 442.1 276.5 164.4 84.1 575.8 97.0 434.6 479.6 571.0 20.4 87.7 1.5 573.1 476.6 894.3 218.6 656.2 200.8 21.1 292.7 595.6 548.3 0.0 0.7 225.3 215.7 613.9 1272.8 72.2 502.0 670.0 528.3 142.4 499.0 211.9 131.8 63.8 0.9 544.8 138.3 397.2 191.7 657.7 138.4 143.7 314.5 9.2 269.5 562.0 714.4 12.2 13.3 2019.8 3223.6 898.7 405.2 157.1 191.1 817.8 ZFP90 "KIAA1954, NK10, ZNF756" ENSG00000184939 "ZFP90 zinc finger protein" Q8TF47 16 68530090-68576072 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029017 Uncertain Supported "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Vesicles, Plasma membrane, Centrosome" "HPA029017: AB_10669653" "unprognostic (3.27e-1)" "unprognostic (1.71e-2)" "unprognostic (1.56e-1)" "unprognostic (1.45e-2)" "unprognostic (3.11e-1)" "unprognostic (2.47e-1)" "unprognostic (3.68e-3)" "unprognostic (1.78e-1)" "unprognostic (5.19e-2)" "unprognostic (7.33e-2)" "unprognostic (1.35e-3)" "unprognostic (3.43e-1)" "prognostic favorable (1.78e-4)" "unprognostic (1.47e-2)" "unprognostic (2.37e-1)" "unprognostic (1.33e-1)" "unprognostic (9.60e-2)" 7.0 6.3 19.4 7.2 18.6 6.1 11.1 27.0 31.1 11.7 9.9 8.2 2.9 10.8 12.2 5.9 9.5 6.5 8.0 18.2 18.1 8.6 5.4 6.7 9.5 15.2 14.6 12.7 7.4 15.7 13.5 5.8 15.3 9.2 6.2 12.7 6.3 8.8 8.2 9.3 7.3 9.3 11.0 10.5 8.1 9.7 18.2 13.4 8.2 9.0 11.3 7.5 8.0 20.3 10.6 11.4 20.9 19.9 18.1 19.2 9.7 9.7 11.0 13.2 15.2 8.0 7.0 11.5 12.7 12.6 11.1 9.7 12.9 12.5 15.0 10.1 4.7 3.0 2.2 13.4 14.0 0.0 10.3 17.2 20.2 12.1 16.8 23.5 10.7 21.2 5.8 4.1 16.3 18.8 11.6 10.7 7.8 6.3 8.5 21.0 6.5 7.6 9.0 7.2 23.5 17.9 28.1 2.1 10.5 15.4 16.8 14.9 8.4 12.2 7.2 10.4 5.8 8.1 15.9 14.0 4.1 4.0 9.9 7.9 1.5 2.5 5.2 1.6 6.7 4.5 4.9 6.0 2.0 3.3 6.7 5.9 0.3 4.3 1.0 2.3 5.8 2.7 19.4 18.6 27.0 31.1 18.2 18.1 15.2 14.6 15.3 11.0 18.2 20.3 13.1 19.2 8.9 18.6 15.1 3.4 6.4 10.5 14.8 21.1 8.5 9.4 10.5 10.0 9.0 20.2 14.6 3.4 11.8 1.5 7.9 10.2 20.6 9.8 14.4 10.9 16.1 13.2 34.0 6.1 1.7 14.7 5.1 6.5 12.0 30.3 11.0 5.2 6.9 18.5 41.4 4.7 4.1 7.9 5.7 13.2 16.4 8.3 3.6 11.2 6.4 13.0 19.6 31.2 35.5 6.5 3.2 17.7 7.2 5.9 1.3 8.1 24.2 17.3 0.0 12.4 11.0 12.1 19.1 8.6 4.5 1.4 18.7 13.7 4.5 4.0 ZFR "SPG71, ZFR1" ENSG00000056097 "Zinc finger RNA binding protein" Q96KR1 5 32354350-32444740 "Predicted intracellular proteins" "Developmental protein, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016666 Supported Approved Nucleoplasm NA NA 8100 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA016666: AB_1859060" "unprognostic (7.45e-3)" "unprognostic (8.46e-2)" "unprognostic (4.07e-3)" "unprognostic (4.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (1.38e-1)" "unprognostic (1.47e-2)" "unprognostic (6.42e-2)" "unprognostic (1.58e-1)" "unprognostic (3.66e-2)" "unprognostic (1.16e-1)" "unprognostic (1.47e-2)" "unprognostic (5.46e-2)" "unprognostic (1.16e-1)" "unprognostic (2.07e-1)" 26.6 28.3 32.2 21.8 36.4 30.9 26.8 32.5 37.6 26.6 23.9 22.1 18.5 27.9 21.7 26.0 27.9 23.6 34.4 34.4 32.2 29.5 24.9 19.5 26.7 31.8 32.2 38.4 26.0 31.3 14.2 35.5 32.2 26.2 22.5 36.7 27.7 24.7 42.4 16.1 21.0 27.4 33.0 22.6 21.2 30.2 32.6 31.6 34.1 41.3 26.3 28.7 17.3 36.8 45.1 65.8 75.4 47.2 81.4 59.3 65.8 68.0 57.3 70.5 50.3 65.9 39.0 65.7 43.2 66.8 92.0 34.4 99.0 48.1 98.4 62.4 55.3 80.5 66.9 65.3 71.2 83.7 63.6 56.7 59.1 74.7 135.8 63.9 53.9 31.9 82.0 53.9 73.1 34.0 73.7 35.4 55.5 47.3 48.7 59.2 101.3 36.1 52.7 73.1 41.9 44.2 101.1 58.2 60.8 53.1 36.1 102.0 61.4 69.5 65.0 51.9 57.4 26.7 50.3 72.6 51.4 66.2 86.2 35.3 15.5 19.8 15.6 24.2 18.1 16.6 14.9 16.1 17.3 13.1 14.2 14.3 10.1 22.9 24.9 9.1 15.1 13.2 32.2 36.4 32.5 37.6 34.4 32.2 31.8 32.2 32.2 33.0 32.6 36.8 48.0 51.3 55.4 80.0 55.1 26.0 70.6 47.0 61.5 61.2 39.4 34.9 108.7 34.3 63.7 31.3 22.9 40.1 51.4 28.3 49.0 51.7 53.1 47.7 62.1 51.6 39.5 36.6 109.5 35.9 31.3 66.0 34.1 48.6 76.5 50.4 40.4 35.8 32.7 77.4 98.5 26.1 52.9 35.8 31.3 35.6 53.1 47.3 30.2 74.0 53.9 70.8 52.5 117.6 171.4 44.9 39.6 60.9 52.3 69.8 28.7 45.6 56.3 55.4 39.5 81.2 70.9 118.5 71.8 53.1 24.6 55.5 50.1 65.3 34.1 55.7 ZFR2 KIAA1086 ENSG00000105278 "Zinc finger RNA binding protein 2" Q9UPR6 19 3804024-3869038 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 17.0;pituitary gland: 26.1;retina: 10.9;testis: 13.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 33.7;Cone photoreceptor cells: 27.1;Early spermatids: 25.3;Excitatory neurons: 39.3;Horizontal cells: 32.0;Inhibitory neurons: 42.7;Rod photoreceptor cells: 38.5;Spermatocytes: 29.4" "Cancer enhanced" "Detected in some" "cervical cancer: 2.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 16.3;NTERA-2: 31.7;SiHa: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043275, HPA055678" Uncertain Approved Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA043275: , HPA055678: AB_2682883" "unprognostic (1.74e-3)" "unprognostic (2.32e-3)" "unprognostic (4.05e-3)" "unprognostic (1.51e-2)" "unprognostic (6.60e-3)" "unprognostic (5.47e-4)" "unprognostic (9.12e-2)" "unprognostic (3.87e-2)" "unprognostic (1.18e-2)" "unprognostic (4.92e-2)" "unprognostic (1.97e-3)" "unprognostic (4.29e-2)" "unprognostic (3.58e-1)" "unprognostic (3.58e-1)" "unprognostic (5.81e-2)" "unprognostic (9.20e-2)" "unprognostic (2.18e-2)" 0.2 2.5 9.6 0.4 9.5 0.2 0.1 0.3 17.0 0.3 0.0 0.5 0.0 0.1 0.0 0.1 0.7 0.1 0.3 7.9 10.9 0.2 0.1 0.3 0.2 3.9 3.0 0.1 0.4 2.5 26.1 0.0 4.0 0.4 0.1 10.9 0.1 0.1 0.1 0.2 0.3 0.0 1.3 0.3 0.3 13.4 8.0 0.0 0.3 0.0 0.2 0.1 0.2 5.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.5 0.8 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 31.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.1 0.5 6.9 0.0 0.4 1.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.3 1.0 0.0 0.0 1.1 0.0 1.2 0.0 0.7 0.5 0.0 0.2 1.0 0.8 0.2 0.4 0.0 0.0 0.2 0.3 9.6 9.5 0.3 17.0 7.9 10.9 3.9 3.0 4.0 1.3 8.0 5.3 0.2 0.0 1.1 2.9 0.2 1.0 0.5 0.1 0.0 33.7 0.2 1.0 1.6 0.0 0.0 0.0 27.1 0.0 1.1 0.0 0.0 0.5 25.3 0.7 0.2 0.5 0.0 0.0 39.3 0.2 0.1 0.2 1.1 0.2 1.3 0.3 0.0 0.1 0.1 32.0 42.7 0.2 0.0 0.0 0.4 11.0 0.9 0.2 1.8 1.9 0.1 4.4 1.0 16.1 4.5 0.2 0.0 0.0 0.3 0.4 0.0 0.3 1.5 38.5 0.0 0.6 0.2 29.4 15.9 0.0 0.1 0.0 1.5 0.1 0.0 0.4 ZFYVE19 "ANCHR, FLJ14840" ENSG00000166140 "Zinc finger FYVE-type containing 19" Q96K21 15 40807086-40815084 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040283, HPA041946" Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA040283: AB_10673369, HPA041946: AB_2677762" "unprognostic (3.59e-2)" "unprognostic (6.62e-2)" "unprognostic (1.15e-2)" "prognostic favorable (7.36e-4)" "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (1.04e-1)" "unprognostic (9.84e-2)" "unprognostic (1.84e-2)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (8.61e-2)" "unprognostic (7.69e-3)" "unprognostic (1.76e-1)" "unprognostic (1.79e-1)" "unprognostic (8.40e-3)" "unprognostic (1.72e-1)" 8.8 8.9 14.2 7.9 16.5 8.6 10.2 19.6 17.2 11.1 12.5 12.0 12.3 8.9 10.7 15.4 9.1 6.6 11.5 13.5 16.9 10.4 19.3 9.1 10.0 19.8 17.4 10.5 8.3 14.1 9.5 9.0 19.1 12.4 8.1 6.6 13.7 8.1 13.5 11.6 12.5 8.8 16.9 13.7 9.6 8.1 18.0 10.9 8.9 13.5 10.5 10.8 11.4 17.5 10.0 12.3 8.8 13.3 13.9 13.9 13.4 15.0 19.4 19.9 20.7 8.9 23.5 9.2 16.5 14.7 17.5 18.0 12.7 17.4 12.1 28.6 12.4 16.6 21.5 11.2 12.5 12.0 24.1 13.5 18.3 13.0 12.6 18.0 19.6 15.2 12.9 11.9 12.7 10.7 15.2 14.8 5.5 22.4 17.6 18.8 5.1 11.4 12.1 19.7 16.0 9.7 13.7 34.6 4.8 6.7 16.4 19.8 9.6 12.4 13.8 9.2 9.9 10.3 14.3 9.8 11.8 22.9 12.4 9.0 5.8 5.2 5.3 9.4 6.2 5.2 5.5 5.2 6.5 3.7 6.0 5.5 3.1 8.9 6.2 5.5 6.1 4.7 14.2 16.5 19.6 17.2 13.5 16.9 19.8 17.4 19.1 16.9 18.0 17.5 11.4 6.4 5.6 6.2 6.6 6.4 13.3 19.7 8.0 11.1 14.8 12.2 9.3 15.7 18.0 12.9 12.5 74.7 5.7 22.6 19.6 24.4 5.3 12.4 8.0 9.7 3.5 5.2 7.6 17.6 16.8 9.6 12.2 12.5 12.7 12.7 10.4 21.8 22.4 3.3 9.4 15.5 22.4 9.9 6.8 10.9 12.8 9.7 7.2 7.5 14.3 9.8 8.2 7.1 15.7 19.3 20.7 9.4 4.2 9.1 50.3 27.4 17.9 10.7 13.1 7.3 9.6 18.6 19.4 7.9 7.7 55.1 9.3 8.9 15.5 15.1 ZFYVE21 "MGC2550, ZF21" ENSG00000100711 "Zinc finger FYVE-type containing 21" Q9BQ24 14 103715730-103733668 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 165.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055721 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA055721: AB_2682896" "unprognostic (1.10e-2)" "unprognostic (3.35e-1)" "unprognostic (8.89e-2)" "unprognostic (7.54e-3)" "unprognostic (1.96e-1)" "unprognostic (8.32e-2)" "unprognostic (4.74e-2)" "unprognostic (1.16e-1)" "unprognostic (1.04e-2)" "unprognostic (5.11e-3)" "unprognostic (5.02e-2)" "unprognostic (9.13e-2)" "prognostic favorable (2.58e-6)" "unprognostic (2.30e-3)" "unprognostic (1.71e-1)" "unprognostic (7.18e-2)" "unprognostic (2.06e-1)" 57.4 28.9 117.0 14.2 121.0 11.9 54.0 115.6 143.1 69.3 113.2 52.3 18.2 70.8 50.3 68.4 71.8 28.4 51.6 112.8 116.0 37.0 34.7 31.6 16.5 121.3 114.4 56.1 26.7 34.1 32.0 30.1 118.0 41.0 25.7 15.2 61.5 53.3 22.0 73.2 31.0 45.6 123.6 28.1 44.9 35.5 120.0 19.3 50.3 29.9 17.5 65.1 67.8 127.4 27.1 34.1 29.1 26.7 76.9 61.6 48.2 49.8 35.2 41.5 36.2 40.2 34.3 6.0 31.5 53.2 29.9 45.4 25.3 59.4 37.3 11.5 30.9 33.5 23.0 55.3 60.8 8.6 21.4 42.1 61.6 18.4 29.8 37.4 51.0 19.6 13.0 11.4 29.9 165.5 23.3 26.8 13.4 41.3 47.9 12.6 21.6 9.2 81.5 95.5 16.6 11.5 35.2 44.3 26.2 32.2 56.6 22.3 44.7 20.1 16.3 68.4 25.6 12.8 13.8 9.2 22.7 18.7 19.5 28.3 36.2 42.1 20.0 57.6 19.8 18.1 18.7 20.1 23.9 24.7 19.4 18.5 29.6 16.3 47.8 19.4 21.7 24.6 117.0 121.0 115.6 143.1 112.8 116.0 121.3 114.4 118.0 123.6 120.0 127.4 68.0 19.2 23.9 61.7 9.5 45.5 83.5 161.9 59.2 27.8 58.8 68.6 36.0 41.5 83.1 80.9 33.3 115.7 20.9 33.6 121.3 56.4 14.2 25.3 54.7 71.0 19.3 76.2 30.9 54.5 40.0 65.3 12.2 30.3 19.7 22.0 66.4 26.9 55.4 20.2 11.8 34.2 81.4 22.6 29.5 23.0 109.6 28.4 103.2 19.7 32.3 91.6 24.7 11.6 21.8 79.3 51.9 197.1 7.4 87.7 31.5 98.9 47.1 29.6 65.7 57.2 60.7 46.3 78.4 50.9 60.2 101.5 13.4 36.3 32.4 81.9 ZG16 "hZG16, JCLN, JCLN1, ZG16A" ENSG00000174992 "Zymogen granule protein 16" O60844 16 29778256-29782973 "Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "intestine: 479.5" "Cell type enriched" "Detected in some" 10 "Intestinal goblet cells: 20216.0" "Cancer enriched" "Detected in some" 6 "colorectal cancer: 21.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-BR-3: 2.3" "Not detected" "Not detected" "HPA052066, HPA052512" Enhanced "Secreted to digestive system" NA NA 1300000 "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA052066: AB_2681716, HPA052512: AB_2681857" "unprognostic (1.64e-2)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (8.20e-2)" "unprognostic (3.50e-2)" "unprognostic (1.93e-2)" "unprognostic (5.14e-2)" "unprognostic (1.65e-1)" "unprognostic (7.77e-2)" "unprognostic (3.27e-1)" "unprognostic (2.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" 0.5 0.0 0.0 7.8 0.2 0.1 0.7 0.1 0.1 0.0 0.0 362.9 57.8 0.6 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.4 22.2 0.0 0.2 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.1 479.5 0.1 0.0 0.5 0.0 0.1 136.9 12.9 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.6 0.0 1107.2 0.0 0.0 0.0 0.1 0.0 0.1 145.5 0.0 0.1 11.9 0.0 0.1 0.0 0.2 40.1 0.0 0.4 44.6 0.0 0.0 0.1 20216.0 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 484.8 0.0 0.0 0.2 1950.6 1.6 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.5 7.1 0.0 306.7 0.3 ZG16B "HRPE773, JCLN2, PRO1567" ENSG00000162078 "Zymogen granule protein 16B" Q96DA0 16 2830169-2839585 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 717 "salivary gland: 63926.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 194.0;Basal respiratory cells: 181.6;Breast glandular cells: 154.9;Club cells: 343.9;Intestinal goblet cells: 232.2;Prostatic glandular cells: 398.1;Urothelial cells: 357.4" "Cancer enhanced" "Detected in many" "prostate cancer: 47.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 6.3;intermediate monocyte: 11.4;non-classical monocyte: 7.4" "Lineage enriched" "Detected in many" 7 "monocytes: 11.4" "Cell line enhanced" "Detected in some" "MCF7: 27.1;OE19: 57.5;SK-BR-3: 24.1;T-47d: 22.2" "Not detected" "Not detected" "HPA041125, HPA053549" Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 690000 "Cluster 7: Monocytes - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "HPA041125: AB_10794264, HPA053549: AB_2682184" "unprognostic (5.29e-2)" "unprognostic (2.71e-1)" "unprognostic (4.37e-2)" "prognostic favorable (3.48e-6)" "unprognostic (1.39e-3)" "unprognostic (1.94e-2)" "unprognostic (2.34e-3)" "unprognostic (4.13e-2)" "unprognostic (1.01e-1)" "unprognostic (3.45e-3)" "unprognostic (1.37e-1)" "unprognostic (1.47e-2)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.17e-1)" "unprognostic (1.04e-1)" "unprognostic (8.33e-2)" 2.5 13.2 0.0 3.9 0.0 4.6 33.1 0.0 0.1 33.0 0.0 13.6 11.5 0.6 1.5 25.3 4.4 34.4 9.0 0.0 0.0 2.6 8.2 3.3 0.3 0.0 0.8 10.3 46.6 30.4 6.0 4.8 0.1 89.1 17.8 0.0 63926.2 7.1 6.1 47.7 9.6 0.4 0.0 4.2 33.2 4.4 0.0 0.2 2.9 0.1 5.9 11.2 16.3 0.0 0.0 1.1 0.0 0.0 0.3 1.9 0.2 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.3 0.0 0.2 2.1 0.0 4.4 0.0 0.0 0.0 9.0 2.8 2.4 1.6 0.0 0.0 0.1 0.2 0.0 1.2 0.1 0.0 0.0 0.2 3.6 0.2 27.1 0.0 0.4 0.1 57.5 5.0 0.0 0.0 8.6 0.2 6.3 0.0 0.0 0.1 24.1 0.0 0.1 22.2 0.0 3.1 0.1 0.5 1.9 0.1 0.0 0.5 0.3 0.3 6.5 0.3 1.7 6.3 0.0 0.0 11.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.4 1.2 7.4 0.0 0.5 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 9.1 194.0 181.6 0.0 0.0 154.9 82.5 0.0 70.1 343.9 1.8 0.0 0.1 2.0 107.1 0.0 5.9 7.7 3.5 1.6 2.8 58.2 0.4 0.0 28.1 3.2 1.8 21.9 13.0 5.7 1.7 0.7 0.1 14.6 0.0 0.0 232.2 140.4 4.6 0.5 5.7 0.0 4.4 83.6 0.0 5.6 0.0 0.0 0.0 0.0 46.4 65.3 0.0 0.0 398.1 12.5 0.0 74.7 0.0 0.0 0.0 19.2 1.4 0.6 9.5 24.0 0.3 2.5 21.3 76.7 357.4 ZHX3 "KIAA0395, TIX1" ENSG00000174306 "Zinc fingers and homeoboxes 3" Q9H4I2 20 41178448-41317672 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 370.5;Early spermatids: 106.3;Excitatory neurons: 99.0;Inhibitory neurons: 96.5;Oligodendrocyte precursor cells: 139.7;Oligodendrocytes: 142.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046498 Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA046498: AB_2679676" "unprognostic (6.26e-2)" "unprognostic (1.41e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.40e-2)" "unprognostic (4.50e-2)" "unprognostic (2.29e-1)" "unprognostic (3.88e-1)" "unprognostic (3.42e-1)" "unprognostic (7.25e-3)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.53e-5)" "unprognostic (3.06e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (7.52e-4)" "prognostic unfavorable (1.84e-5)" 14.4 15.4 33.8 6.5 32.8 3.4 13.3 31.6 27.4 11.6 16.4 19.8 8.6 15.8 5.7 13.6 15.7 8.4 12.2 30.2 27.7 26.4 17.2 11.6 4.5 37.6 32.1 16.3 11.9 15.4 7.8 4.9 29.9 10.6 8.0 10.8 5.7 11.9 28.5 11.0 11.4 12.1 29.4 4.3 15.5 35.0 36.0 7.0 19.0 20.1 4.8 18.1 11.0 28.6 22.5 6.3 6.6 14.2 52.6 56.3 7.6 31.0 35.4 28.3 19.1 11.4 2.9 15.6 14.7 58.5 7.6 7.0 7.9 39.2 30.0 4.3 7.1 6.6 8.6 8.8 21.6 7.6 7.9 34.6 18.7 21.3 27.3 19.2 12.3 11.7 6.2 10.6 38.3 45.0 11.9 4.5 2.9 10.4 23.0 5.8 18.6 6.2 38.6 6.7 23.0 8.3 20.7 12.0 7.4 5.7 11.6 10.5 19.9 70.2 10.8 25.0 15.5 12.2 8.0 6.9 28.9 11.0 11.4 0.1 0.1 0.4 0.2 0.1 0.4 0.6 0.2 0.1 0.2 0.6 0.4 0.3 0.1 0.6 0.2 0.1 0.2 0.1 33.8 32.8 31.6 27.4 30.2 27.7 37.6 32.1 29.9 29.4 36.0 28.6 29.8 19.2 16.4 370.5 4.7 2.9 3.9 2.6 2.8 19.5 6.3 4.7 12.7 17.2 5.8 22.0 4.2 0.6 3.8 5.5 11.7 3.7 106.3 12.3 33.2 15.1 14.9 3.8 99.0 2.7 2.7 20.5 6.6 26.3 1.3 3.7 16.4 31.6 3.0 40.4 96.5 5.6 4.1 3.5 1.7 32.3 18.6 3.5 1.8 52.5 1.9 28.6 1.0 139.7 142.4 4.6 1.3 24.5 2.7 2.6 12.6 27.0 3.2 7.1 26.3 41.2 10.9 11.0 5.2 6.3 3.7 0.4 2.7 19.7 4.7 2.3 ZIC4 ENSG00000174963 "Zic family member 4" Q8N9L1 3 147386046-147406809 "Human disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 68.5" "Cell type enhanced" "Detected in some" "Early spermatids: 5.0;Late spermatids: 13.5;Microglial cells: 6.5;Muller glia cells: 5.5;Oligodendrocytes: 6.9;Skeletal myocytes: 6.2" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Region enriched" "Detected in all" 4 "cerebellum: 68.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 16.5;ASC diff: 4.7;BEWO: 3.5;MCF7: 4.7;SH-SY5Y: 4.9;U-2197: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 8 "cerebellum: 67.3" HPA030194 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA030194: AB_2673367" "unprognostic (1.12e-1)" "unprognostic (9.95e-2)" "unprognostic (5.59e-3)" "unprognostic (1.02e-1)" "unprognostic (6.83e-2)" "unprognostic (1.10e-1)" "unprognostic (2.20e-1)" "unprognostic (9.13e-2)" "unprognostic (1.10e-10)" "unprognostic (3.50e-2)" "unprognostic (8.69e-2)" 0.6 0.0 1.9 0.0 6.6 0.0 0.0 68.5 4.7 0.0 5.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.7 5.5 0.0 0.3 0.0 0.0 10.6 5.8 0.0 0.0 0.0 0.1 0.0 9.0 0.0 0.0 4.8 0.0 0.0 1.3 1.2 0.1 0.0 2.7 0.0 0.0 0.5 10.5 0.0 0.0 0.0 0.0 0.0 0.0 15.3 0.0 0.0 16.5 0.0 4.7 1.9 3.5 1.8 0.4 0.2 0.5 0.0 0.0 0.0 2.1 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.4 4.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 4.9 0.0 0.0 2.1 0.0 0.0 0.0 0.0 1.1 0.0 3.9 1.8 0.0 0.0 0.0 1.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 6.6 68.5 4.7 1.7 5.5 10.6 5.8 9.0 2.7 10.5 15.3 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 6.5 0.0 5.5 0.0 0.5 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 6.2 0.1 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZMAT1 KIAA1789 ENSG00000166432 "Zinc finger matrin-type 1" Q5H9K5 X 101882288-101932079 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 190.3;Oligodendrocyte precursor cells: 111.1;Oligodendrocytes: 112.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 8.2;U-266/70: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012827 Enhanced Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA012827: AB_1859070" "unprognostic (9.30e-2)" "unprognostic (4.13e-2)" "unprognostic (2.51e-2)" "unprognostic (2.80e-1)" "unprognostic (1.08e-1)" "unprognostic (1.08e-5)" "unprognostic (1.20e-3)" "unprognostic (2.22e-2)" "unprognostic (3.70e-2)" "unprognostic (6.09e-2)" "prognostic favorable (1.72e-5)" "unprognostic (6.33e-3)" "unprognostic (1.72e-2)" "unprognostic (3.05e-1)" "unprognostic (5.28e-2)" "unprognostic (2.21e-1)" "unprognostic (1.38e-2)" 6.4 9.3 11.1 2.8 11.5 6.3 7.5 10.5 15.1 8.0 10.6 7.3 1.8 5.5 21.2 2.4 10.0 2.1 7.9 10.7 10.7 18.3 9.7 5.7 6.6 11.5 10.9 15.2 10.3 4.3 34.8 0.7 11.0 10.7 1.3 9.4 6.7 3.7 2.6 3.0 7.5 1.3 11.1 13.8 5.8 6.7 10.9 3.2 25.0 1.5 2.6 6.0 4.8 12.1 0.2 0.0 1.0 1.0 0.0 0.0 0.1 0.4 0.0 0.0 0.4 0.0 1.2 1.8 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.2 0.2 0.7 1.9 0.0 8.2 0.6 0.0 0.1 0.1 1.3 0.0 0.1 1.5 0.0 0.1 2.3 0.0 0.4 1.1 0.7 0.0 0.1 1.1 1.4 2.1 2.0 0.6 0.0 0.0 0.1 4.1 0.3 0.0 0.4 2.0 0.6 0.8 0.3 0.5 0.2 0.1 0.4 0.6 0.3 0.4 0.0 0.9 0.4 0.3 0.2 0.1 0.1 0.9 0.2 0.1 11.1 11.5 10.5 15.1 10.7 10.7 11.5 10.9 11.0 11.1 10.9 12.1 18.9 16.0 31.2 190.3 30.2 4.1 7.6 0.2 7.4 38.1 18.2 12.3 25.4 11.5 14.4 14.7 43.8 0.1 16.5 0.6 3.9 5.0 14.9 28.2 3.7 16.8 10.3 6.9 30.7 2.7 0.0 10.3 2.0 21.6 15.8 51.5 13.6 10.6 3.3 16.8 32.8 2.8 0.0 9.7 11.1 9.7 1.8 11.7 7.2 71.2 10.7 25.8 10.3 111.1 112.8 1.5 1.6 1.2 7.4 6.1 2.7 5.7 13.0 57.5 0.0 27.5 9.0 22.4 10.2 3.2 2.8 0.1 16.3 5.4 2.6 4.3 ZNF148 "BERF-1, BFCOL1, HT-BETA, pHZ-52, ZBP-89, ZFP148" ENSG00000163848 "Zinc finger protein 148" Q9UQR1 3 125225669-125375325 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001656, CAB017486" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Golgi apparatus" "CAB017486: AB_794260, HPA001656: AB_1079995" "unprognostic (2.40e-1)" "unprognostic (1.12e-2)" "unprognostic (5.03e-2)" "unprognostic (3.94e-2)" "unprognostic (5.94e-3)" "unprognostic (5.66e-2)" "unprognostic (1.24e-2)" "unprognostic (2.36e-1)" "unprognostic (1.69e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (2.88e-4)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (3.63e-2)" "unprognostic (2.72e-1)" 8.9 7.5 5.6 9.4 8.9 7.9 12.1 12.9 7.8 12.6 0.0 10.8 7.6 13.9 10.2 10.3 12.4 9.5 15.5 4.5 16.4 12.9 11.7 10.3 12.3 4.2 6.5 17.4 9.5 15.8 4.7 9.7 4.2 11.1 11.5 13.1 10.0 11.1 11.1 5.8 8.9 13.7 2.3 11.9 9.8 10.5 14.5 16.9 30.0 12.0 14.4 10.6 6.1 8.3 30.6 19.8 21.1 18.9 18.4 19.7 16.0 27.2 31.5 29.9 28.4 19.1 16.6 24.4 18.5 40.3 24.1 24.4 23.2 20.5 42.4 10.9 8.9 30.1 23.3 9.8 13.6 20.9 29.1 16.1 21.0 28.0 29.4 19.7 20.7 17.7 15.0 20.2 22.3 23.9 26.1 7.7 13.6 20.6 16.8 18.6 23.2 13.9 17.1 33.6 18.2 15.3 36.2 18.2 29.7 11.7 22.7 20.8 26.6 22.6 24.1 28.5 17.5 17.4 21.5 36.6 16.9 13.1 21.3 4.4 15.3 32.0 21.8 14.5 22.5 24.5 19.2 20.9 13.0 22.2 27.9 22.0 51.4 33.2 23.4 11.3 19.6 20.1 5.6 8.9 12.9 7.8 4.5 16.4 4.2 6.5 4.2 2.3 14.5 8.3 54.7 93.0 41.3 92.7 56.7 35.6 26.0 36.2 48.9 68.0 37.0 35.7 75.2 24.3 43.0 33.1 39.6 28.7 53.7 34.7 25.4 37.5 82.0 28.8 54.3 51.6 47.9 32.0 166.7 37.4 24.3 44.5 31.1 38.1 50.6 75.7 37.9 41.0 31.1 75.7 170.3 34.4 26.4 37.1 21.2 135.2 48.1 41.2 17.8 143.4 50.1 45.7 59.8 154.3 151.4 33.7 25.6 59.0 35.8 36.6 28.2 43.9 27.5 39.4 32.9 63.4 60.7 24.4 24.2 32.5 38.4 31.6 52.0 42.0 33.6 35.6 ZNF207 BuGZ ENSG00000010244 "Zinc finger protein 207" O43670 17 32350132-32381885 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017013, HPA063908" Enhanced Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA017013: AB_1859124, HPA063908: AB_2685149" "unprognostic (8.40e-3)" "unprognostic (1.84e-1)" "prognostic favorable (2.81e-4)" "unprognostic (7.57e-2)" "unprognostic (2.44e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.30e-8)" "unprognostic (2.68e-1)" "unprognostic (4.75e-3)" "unprognostic (8.53e-2)" "unprognostic (5.18e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (4.17e-8)" "unprognostic (1.28e-2)" "unprognostic (2.06e-1)" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" 71.8 65.5 36.8 74.0 40.2 239.5 67.8 50.3 45.3 72.0 44.4 68.7 55.1 70.6 72.0 111.1 62.3 58.5 60.5 38.6 37.7 63.2 63.4 72.3 101.0 39.3 37.2 71.7 55.3 72.0 61.3 78.7 40.7 57.2 81.3 61.9 71.6 56.4 84.5 76.3 63.6 77.8 40.7 69.3 63.6 66.3 39.4 103.8 63.0 62.1 128.6 93.2 78.2 48.0 169.9 203.5 215.8 122.4 113.0 121.3 172.6 165.5 231.9 230.1 205.3 195.2 157.3 231.5 124.8 204.6 178.5 170.6 282.1 200.6 258.1 120.0 188.9 237.9 183.8 202.9 118.2 305.0 209.4 141.3 118.3 162.0 89.6 129.4 215.9 115.5 245.9 173.2 223.9 154.6 245.2 142.5 187.1 160.8 114.8 217.5 193.5 217.0 191.5 324.9 150.6 167.7 155.8 113.2 148.1 183.9 204.8 178.7 154.1 129.4 153.4 132.5 227.8 146.7 235.6 369.5 110.6 141.9 204.9 110.5 75.7 78.1 67.6 84.8 70.2 59.7 61.7 62.7 99.8 44.7 50.8 59.1 38.6 83.9 92.5 47.1 86.9 90.6 36.8 40.2 50.3 45.3 38.6 37.7 39.3 37.2 40.7 40.7 39.4 48.0 119.3 80.1 114.7 135.8 131.1 149.4 195.5 120.8 149.1 134.2 108.8 64.1 32.9 65.8 146.1 64.4 225.2 123.3 191.1 118.2 54.8 94.9 62.0 101.9 116.9 110.1 115.9 125.1 171.2 105.7 175.5 101.3 124.9 144.2 75.3 152.8 85.3 58.4 98.7 101.0 163.0 95.2 93.6 98.8 130.2 26.1 107.2 133.1 55.2 123.7 175.8 55.0 168.9 215.7 257.4 146.5 91.2 97.8 144.9 160.3 101.7 57.7 115.0 141.0 124.9 146.3 145.6 136.3 113.5 175.9 148.5 178.7 143.8 90.0 109.9 250.3 ZNF281 ZBP-99 ENSG00000162702 "Zinc finger protein 281" Q9Y2X9 1 200404940-200410056 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 33.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051228 Uncertain Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA051228: AB_2681396" "unprognostic (3.13e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.50e-1)" "unprognostic (8.99e-3)" "unprognostic (1.23e-1)" "unprognostic (5.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.92e-2)" "unprognostic (3.71e-3)" "unprognostic (8.30e-2)" "unprognostic (3.69e-2)" "unprognostic (5.99e-2)" "prognostic unfavorable (2.60e-5)" "unprognostic (1.26e-2)" "unprognostic (4.86e-1)" "unprognostic (6.19e-2)" "unprognostic (1.83e-1)" 7.7 3.3 6.3 10.7 12.0 33.5 7.9 10.8 9.8 6.9 4.2 4.6 5.4 7.0 3.9 3.2 4.3 10.1 4.2 7.1 7.6 7.1 21.6 7.5 11.3 8.8 8.9 5.7 5.7 5.6 2.6 8.9 8.3 4.7 4.3 10.7 5.5 4.3 5.7 2.7 4.1 9.0 7.0 9.7 5.1 9.6 8.6 12.6 5.1 7.9 11.7 7.9 2.0 20.7 19.9 19.8 27.2 12.5 10.8 14.5 22.2 21.0 33.3 21.0 19.6 19.7 15.7 29.0 11.6 24.2 24.4 13.4 29.6 19.7 24.9 30.6 17.5 23.6 15.6 20.4 11.6 21.3 12.9 14.1 21.9 22.6 24.5 26.2 19.1 15.6 33.9 4.6 21.5 9.8 22.5 13.8 61.1 6.3 17.1 20.6 18.8 17.2 21.7 10.3 9.2 24.4 21.1 13.8 18.6 42.4 27.0 15.4 25.7 38.1 28.2 8.7 22.3 16.8 17.8 37.0 20.2 16.8 20.5 15.2 8.1 30.3 9.9 8.5 9.7 10.7 8.3 10.4 8.0 9.1 13.6 11.9 38.1 8.1 8.3 8.3 10.9 3.4 6.3 12.0 10.8 9.8 7.1 7.6 8.8 8.9 8.3 7.0 8.6 20.7 30.2 64.1 40.3 7.2 35.1 48.2 26.2 24.0 37.5 55.1 46.3 26.9 14.5 28.6 25.9 27.6 29.2 15.4 24.6 13.8 13.7 22.1 2.6 21.6 37.1 38.9 26.8 22.9 16.0 10.5 31.0 21.2 11.2 41.4 6.3 16.3 30.0 76.9 19.6 18.5 19.6 11.4 8.2 52.1 25.8 3.6 9.9 43.5 23.2 15.0 30.6 15.5 26.8 22.6 59.4 17.8 13.3 7.9 31.7 25.4 10.9 20.3 20.5 37.0 13.1 21.1 32.9 50.1 42.4 18.9 22.7 12.3 29.5 14.2 12.9 20.4 ZNF317 ENSG00000130803 "Zinc finger protein 317" Q96PQ6 19 9140397-9163424 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042075, HPA048625" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "HPA042075: AB_10796471, HPA048625: AB_2680464" "unprognostic (3.81e-1)" "unprognostic (3.11e-2)" "unprognostic (3.90e-1)" "unprognostic (1.63e-1)" "unprognostic (2.98e-2)" "unprognostic (6.07e-3)" "unprognostic (7.70e-2)" "unprognostic (6.17e-2)" "unprognostic (3.89e-2)" "unprognostic (1.72e-2)" "unprognostic (1.18e-1)" "unprognostic (1.14e-1)" "unprognostic (1.67e-3)" "unprognostic (1.30e-3)" "unprognostic (2.30e-1)" "unprognostic (3.36e-1)" "unprognostic (2.42e-3)" 15.8 17.5 21.3 10.2 22.0 26.2 14.7 22.4 34.1 15.1 22.3 17.4 11.2 16.4 11.5 17.4 15.5 8.3 16.1 21.4 21.8 22.2 21.1 14.2 14.2 21.4 21.6 16.4 19.6 12.4 15.8 9.1 21.3 17.8 10.4 12.9 13.6 9.6 14.6 22.8 17.9 10.3 21.3 24.7 18.3 6.7 21.9 15.0 14.5 12.7 15.3 17.7 15.1 22.7 17.4 14.6 15.7 21.0 15.7 14.9 13.6 14.3 22.3 19.2 23.2 16.6 9.2 29.5 17.9 15.3 22.8 17.2 25.7 24.7 24.8 24.4 34.5 26.6 13.3 18.4 20.9 27.8 26.0 17.9 32.2 21.9 38.1 16.6 17.0 25.8 24.8 33.6 19.6 14.6 34.8 88.3 29.0 18.4 30.9 24.4 19.8 23.6 17.0 29.4 27.0 18.6 19.9 17.4 22.7 13.7 13.1 28.7 15.1 13.6 12.3 31.2 19.3 42.0 42.8 33.3 13.1 24.2 17.8 19.4 14.8 16.1 13.0 15.5 20.5 20.8 17.3 15.2 15.0 16.4 16.4 17.9 9.0 22.8 13.4 13.6 22.5 14.2 21.3 22.0 22.4 34.1 21.4 21.8 21.4 21.6 21.3 21.3 21.9 22.7 5.7 9.6 13.4 6.8 11.8 7.4 7.1 4.4 6.2 8.3 8.9 6.7 7.3 7.2 9.4 5.5 6.2 5.6 12.6 9.5 3.9 5.3 0.7 8.9 9.0 7.6 7.2 9.1 6.1 6.4 5.2 7.9 12.2 13.1 13.9 8.1 6.4 10.1 8.0 8.4 7.4 8.6 6.1 15.9 6.2 1.4 3.7 10.1 5.4 7.5 8.1 4.6 8.2 10.6 9.3 8.5 4.7 3.8 10.5 9.5 5.8 9.8 9.4 5.3 0.0 5.7 5.4 2.4 1.0 7.0 6.5 10.9 10.3 7.7 9.6 11.7 ZNF34 KOX32 ENSG00000196378 "Zinc finger protein 34" Q8IZ26 8 144772224-144787345 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053925, HPA060755, HPA066805" Uncertain Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA053925: AB_2682311, HPA060755: AB_2684354, HPA066805: AB_2685725" "unprognostic (2.54e-1)" "unprognostic (3.50e-1)" "unprognostic (5.01e-2)" "unprognostic (7.60e-2)" "unprognostic (1.98e-1)" "unprognostic (1.67e-2)" "unprognostic (3.26e-2)" "unprognostic (3.54e-2)" "unprognostic (2.85e-2)" "unprognostic (1.40e-2)" "unprognostic (9.84e-3)" "unprognostic (1.46e-1)" "unprognostic (3.46e-3)" "unprognostic (5.80e-2)" "unprognostic (2.09e-3)" "unprognostic (1.56e-1)" "unprognostic (1.30e-1)" 9.3 4.2 8.5 2.8 9.3 3.3 8.6 12.8 10.5 10.4 8.1 10.2 2.2 9.1 4.7 3.8 10.0 3.6 5.8 8.6 9.4 6.0 5.0 5.5 3.9 9.0 9.0 10.8 5.1 6.2 9.7 4.7 9.6 7.5 3.6 12.4 4.5 7.3 6.3 8.1 5.6 6.6 8.4 4.9 5.6 6.4 9.0 5.4 8.2 6.4 3.0 9.1 7.4 10.9 2.1 3.0 5.7 4.7 4.7 4.8 1.4 1.8 4.1 4.6 3.8 0.8 3.3 3.1 3.4 4.9 2.6 2.0 3.4 3.9 3.6 2.9 2.8 6.3 5.4 2.7 4.3 1.8 3.4 4.8 4.4 3.5 7.7 5.0 3.2 2.0 4.2 2.6 4.1 5.0 3.8 2.7 3.9 4.7 3.3 3.3 2.1 4.1 2.6 2.2 5.6 4.0 4.1 3.0 3.1 3.6 3.2 2.3 2.0 4.3 3.9 3.4 3.9 3.4 1.2 3.9 3.1 2.7 5.1 8.2 6.7 12.9 6.6 6.5 5.7 7.2 6.2 7.8 10.2 7.4 4.3 6.5 1.0 6.1 16.3 4.8 5.1 4.8 8.5 9.3 12.8 10.5 8.6 9.4 9.0 9.0 9.6 8.4 9.0 10.9 17.2 6.4 5.1 3.3 5.5 3.7 2.8 3.9 5.2 7.8 4.6 9.1 3.0 1.5 3.9 0.0 0.0 2.7 2.4 1.4 5.9 3.0 10.6 3.2 7.7 7.9 0.0 1.7 4.8 1.3 3.1 6.7 1.1 4.9 5.1 3.8 2.9 2.1 1.8 13.5 6.2 1.7 6.1 1.2 4.5 7.9 7.2 4.1 3.6 2.8 8.2 6.2 2.1 3.0 8.2 1.1 3.2 4.9 2.7 2.0 2.8 2.3 1.1 9.1 6.6 8.5 7.5 16.4 9.9 8.4 4.8 2.3 4.9 4.2 2.3 0.9 ZNF385A "DKFZp586G1122, Hzf, ZFP385, ZNF385" ENSG00000161642 "Zinc finger protein 385A" Q96PM9 12 54369133-54391298 "Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation, Translation regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.3;retina: 250.6;skin 1: 159.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 212.8;Cone photoreceptor cells: 171.0;Horizontal cells: 144.7;Muller glia cells: 142.6;Rod photoreceptor cells: 209.7;Syncytiotrophoblasts: 108.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 29.2;intermediate monocyte: 32.8;myeloid DC: 31.9;non-classical monocyte: 25.7" "Group enriched" "Detected in many" 11 "dendritic cells: 31.9;monocytes: 32.8" "Cell line enhanced" "Detected in many" "HaCaT: 89.5;HBEC3-KT: 85.7;HEL: 109.5;hTCEpi: 94.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039799 Supported Nucleoplasm,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "HPA039799: AB_10795117" "unprognostic (8.56e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (5.20e-4)" "unprognostic (6.70e-2)" "unprognostic (1.07e-2)" "unprognostic (1.79e-3)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.42e-1)" "unprognostic (2.12e-1)" "prognostic unfavorable (9.75e-5)" "unprognostic (1.00e-1)" "unprognostic (3.68e-2)" "unprognostic (2.43e-1)" "unprognostic (6.07e-3)" 43.3 10.1 76.8 28.6 87.9 32.8 22.2 96.9 86.3 29.2 57.7 13.8 7.2 7.6 16.6 99.5 9.7 14.2 13.7 60.2 89.8 10.2 6.4 19.1 15.3 105.5 111.9 5.3 3.3 26.6 26.7 19.4 93.9 34.9 8.0 250.6 28.1 15.0 21.9 159.8 15.8 14.2 95.1 24.8 10.4 2.4 159.3 12.1 40.8 23.3 20.3 38.8 55.8 65.1 2.5 10.7 15.9 20.0 17.9 12.0 43.6 2.1 8.1 8.3 7.1 21.8 7.8 5.9 7.2 4.4 6.7 89.5 6.1 85.7 2.8 5.8 8.5 109.5 6.6 4.3 8.0 1.6 73.4 10.7 94.8 9.3 23.5 20.3 5.2 15.0 53.6 0.5 3.8 49.9 5.4 15.9 9.2 10.1 8.3 19.5 1.3 21.7 6.5 71.0 7.0 31.6 0.8 59.7 4.5 18.3 71.0 45.5 5.3 4.4 10.2 5.4 5.6 1.7 0.5 5.3 18.6 5.0 11.8 3.0 29.2 0.0 0.0 32.8 0.0 1.3 0.0 0.0 31.9 1.3 0.0 0.4 2.2 0.1 25.7 3.0 0.1 16.5 76.8 87.9 96.9 86.3 60.2 89.8 105.5 111.9 93.9 95.1 159.3 65.1 8.3 0.0 0.0 12.1 7.3 36.2 21.3 76.5 49.5 212.8 16.7 13.8 3.2 1.5 20.4 9.2 171.0 63.9 2.5 0.2 9.8 3.4 0.5 13.3 9.8 8.8 4.8 9.2 5.4 0.6 9.4 29.6 3.6 2.2 1.3 4.8 4.6 1.3 56.4 144.7 13.5 0.1 12.2 71.6 54.7 0.5 14.9 78.0 8.8 6.5 49.4 142.6 3.1 3.5 0.9 1.8 0.1 9.1 2.0 13.1 0.0 2.8 12.1 209.7 0.0 4.0 12.3 2.6 3.6 68.3 66.1 108.9 2.2 0.2 0.1 29.7 ZNF385C ENSG00000187595 "Zinc finger protein 385C" Q66K41 17 42025576-42098479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8;testis: 8.6" "Cell type enriched" "Detected in many" 4 "Early spermatids: 27.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 10 "dendritic cells: 1.5" "Cell line enhanced" "Detected in some" "HDLM-2: 4.3;Hep G2: 16.6;MOLT-4: 4.9;SCLC-21H: 8.6" "Region enriched" "Detected in many" 12 "cerebellum: 28.2" "Region enhanced" "Detected in all" "cerebellum: 19.7" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (1.58e-3)" "unprognostic (3.38e-2)" "unprognostic (2.02e-3)" "unprognostic (3.95e-2)" "unprognostic (3.95e-2)" "unprognostic (2.61e-1)" "unprognostic (3.07e-1)" "unprognostic (2.64e-1)" "unprognostic (2.48e-1)" "unprognostic (8.67e-3)" "unprognostic (1.10e-1)" "unprognostic (8.90e-2)" "unprognostic (2.59e-1)" "unprognostic (8.71e-2)" "unprognostic (1.50e-1)" "unprognostic (6.22e-2)" "unprognostic (6.05e-2)" 0.5 0.1 2.5 0.3 2.6 0.9 1.6 12.8 3.1 0.8 1.6 0.5 0.1 0.9 1.3 0.6 1.9 0.3 0.3 2.5 3.2 0.9 0.3 0.5 0.5 2.7 3.1 2.5 2.1 0.9 2.5 0.4 3.3 1.2 0.3 4.9 1.5 0.6 2.1 0.7 0.4 0.2 2.1 0.3 0.4 8.6 2.9 1.8 0.5 5.3 0.3 0.4 0.7 2.9 0.3 0.1 0.8 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.4 1.8 0.0 0.6 0.0 0.0 0.5 0.3 0.1 0.0 4.3 3.2 0.2 0.1 16.6 0.3 0.0 0.4 0.0 2.5 0.0 0.6 0.1 0.0 2.5 0.2 0.0 0.0 0.4 4.9 0.2 0.6 0.8 0.0 0.3 0.0 1.0 0.1 0.2 8.6 0.3 0.1 0.4 0.4 0.9 1.6 1.2 0.0 0.0 0.2 0.1 0.0 1.2 0.4 0.3 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 2.5 2.6 12.8 3.1 2.5 3.2 2.7 3.1 3.3 2.1 2.9 2.9 0.6 0.0 0.5 1.6 0.5 0.4 1.9 2.2 0.0 5.0 1.2 2.2 0.5 1.5 1.5 1.8 0.0 0.2 2.7 0.4 1.9 0.5 27.3 0.3 0.3 0.3 0.0 0.0 2.1 0.5 0.1 0.5 0.5 0.7 0.0 0.8 0.0 0.0 0.8 1.7 3.0 0.5 2.0 0.6 0.9 5.1 1.5 0.3 0.0 5.6 0.0 3.0 1.0 3.5 4.2 0.2 0.3 0.0 0.0 4.1 0.6 0.1 0.5 2.2 0.0 1.4 0.5 1.0 1.9 0.0 0.6 0.0 0.2 0.0 0.6 1.3 ZNF385D "FLJ22419, ZNF659" ENSG00000151789 "Zinc finger protein 385D" Q9H6B1 3 21412218-22373321 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 44.0;testis: 15.1" "Cell type enriched" "Detected in many" 5 "Inhibitory neurons: 1766.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 8 "cerebellum: 44.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.8;hTERT-RPE1: 5.4;LHCN-M2: 5.3;PC-3: 5.3;RPTEC TERT1: 15.1;U-87 MG: 21.1" "Low region specificity" "Detected in all" HPA036190 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA036190: AB_10602355" "unprognostic (4.07e-2)" "unprognostic (1.26e-1)" "unprognostic (5.44e-2)" "unprognostic (3.23e-2)" "unprognostic (1.64e-1)" "unprognostic (1.74e-1)" "unprognostic (8.20e-2)" "unprognostic (6.60e-2)" "unprognostic (7.84e-2)" "unprognostic (3.73e-1)" "unprognostic (2.35e-1)" "unprognostic (9.01e-2)" "unprognostic (3.49e-7)" "unprognostic (8.70e-3)" "unprognostic (5.38e-2)" "unprognostic (7.76e-3)" "unprognostic (2.15e-5)" 3.8 0.2 2.6 1.4 4.5 0.3 2.2 44.0 5.4 1.8 0.0 0.8 0.3 1.1 0.5 2.0 0.7 2.7 1.8 1.7 2.5 1.4 0.1 0.6 0.8 3.3 4.5 0.6 0.6 0.2 0.1 0.0 3.6 1.3 0.5 7.3 0.7 1.1 1.0 0.7 0.5 1.7 1.5 0.3 0.4 15.1 3.1 0.7 0.5 3.3 1.0 2.7 1.2 5.3 0.0 0.0 0.3 0.0 2.0 4.3 0.1 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.2 0.0 5.4 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.5 0.0 5.3 0.0 0.0 0.0 15.1 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.1 0.0 0.0 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 2.6 4.5 44.0 5.4 1.7 2.5 3.3 4.5 3.6 1.5 3.1 5.3 82.2 12.8 13.4 17.3 1.4 9.7 0.7 6.2 1.8 58.8 1.5 6.3 3.6 1.5 19.2 1.8 8.4 0.3 1.4 0.9 27.4 0.6 174.9 0.2 1.9 89.0 0.0 12.6 267.5 0.7 0.2 20.5 0.0 0.3 5.1 1.8 2.2 5.8 0.4 323.0 1766.6 0.7 0.0 0.0 14.0 274.5 16.8 4.9 12.4 64.6 0.6 114.3 1.0 159.3 12.7 1.4 0.6 13.5 0.3 1.7 2.3 6.6 4.4 31.0 13.1 22.0 20.2 50.4 2.0 0.6 7.7 0.1 1.5 34.3 0.7 1.0 ZNF395 "DKFZp434K1210, HDBP2, PBF, PRF-1" ENSG00000186918 "Zinc finger protein 395" Q9H8N7 8 28345590-28402701 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 140.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049382, HPA076275" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA049382: , HPA076275: " "unprognostic (1.28e-1)" "unprognostic (3.02e-1)" "unprognostic (1.95e-2)" "unprognostic (2.01e-1)" "unprognostic (1.61e-2)" "unprognostic (4.51e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (9.35e-3)" "unprognostic (8.90e-2)" "unprognostic (2.15e-2)" "unprognostic (7.08e-2)" "unprognostic (2.25e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (1.35e-1)" "unprognostic (1.32e-1)" "unprognostic (2.46e-2)" "unprognostic (7.42e-2)" 33.0 18.5 21.9 14.4 22.1 37.5 30.5 14.9 20.8 23.1 27.6 25.7 20.9 17.4 13.9 47.6 27.2 14.5 27.2 18.3 17.3 23.4 37.0 19.7 21.3 25.7 18.5 53.6 47.5 17.7 16.4 33.9 19.3 23.7 13.9 27.1 38.8 17.5 16.3 42.9 24.7 9.5 19.4 21.8 26.2 10.9 26.7 18.9 18.6 13.9 25.2 26.3 29.3 20.7 140.0 19.4 17.9 48.7 13.9 19.6 52.6 16.2 28.4 13.2 30.6 31.0 24.0 66.1 56.2 25.7 30.5 29.3 16.1 40.6 25.6 11.0 12.7 16.4 3.8 6.5 14.2 7.3 6.6 34.9 55.3 2.3 34.3 37.5 6.5 21.2 16.9 14.2 18.3 23.7 31.6 21.7 28.1 33.9 22.7 29.3 19.7 22.1 30.6 26.4 48.1 50.9 3.8 10.3 26.5 15.8 18.9 16.3 1.5 26.6 32.9 15.1 6.6 17.4 9.6 42.9 72.8 13.6 21.5 10.0 4.3 11.5 4.6 0.8 4.4 11.4 5.5 5.6 1.6 13.7 7.1 4.8 1.9 3.7 0.7 6.2 2.4 2.2 21.9 22.1 14.9 20.8 18.3 17.3 25.7 18.5 19.3 19.4 26.7 20.7 14.8 32.1 22.7 45.7 24.7 16.8 17.2 33.0 45.5 10.3 19.1 16.0 12.4 12.8 20.5 9.2 14.6 17.1 9.3 18.4 3.9 22.5 0.6 18.0 9.9 15.1 27.2 8.6 15.9 24.1 21.6 15.8 11.2 21.8 11.4 11.9 26.0 32.4 5.8 6.7 10.8 21.7 6.1 16.8 6.0 1.5 24.8 5.6 10.6 17.8 7.1 17.4 7.2 15.6 18.3 23.7 8.5 18.0 9.0 14.8 21.9 7.6 19.1 10.2 26.3 25.8 11.6 1.1 3.2 29.2 11.5 6.3 7.9 4.9 27.2 9.7 ZNF415 ENSG00000170954 "Zinc finger protein 415" Q09FC8 19 53107879-53133077 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 108.2;Late spermatids: 54.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 21.9" HPA005553 Approved Approved "Nucleoli fibrillar center,Microtubules" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli fibrillar center, Microtubules" "HPA005553: AB_1859252" "unprognostic (2.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.83e-1)" "unprognostic (9.31e-2)" "unprognostic (6.30e-2)" "unprognostic (1.29e-3)" "unprognostic (2.18e-1)" "unprognostic (3.24e-2)" "unprognostic (4.05e-2)" "unprognostic (1.15e-1)" "unprognostic (7.28e-3)" "unprognostic (1.51e-1)" "unprognostic (1.06e-2)" "unprognostic (4.27e-2)" "unprognostic (1.28e-1)" "unprognostic (4.38e-2)" "unprognostic (2.84e-2)" 6.7 17.8 14.1 2.0 17.7 0.9 8.5 18.7 18.8 7.5 9.9 7.7 2.0 7.5 13.5 3.4 6.4 5.4 16.7 14.6 16.8 7.0 1.2 4.8 3.2 15.8 15.9 9.5 5.6 11.3 5.3 4.2 16.2 9.7 5.2 10.6 6.2 7.7 4.4 3.9 3.3 7.0 13.2 5.4 5.0 21.6 16.4 4.9 10.8 6.7 2.8 6.4 5.1 27.5 0.2 0.0 4.9 14.2 0.7 0.8 11.3 5.3 8.3 7.6 11.5 9.2 0.3 0.0 2.9 9.2 8.8 0.2 0.0 0.0 7.5 0.0 0.7 0.0 0.5 0.0 2.7 0.0 7.8 8.5 0.1 1.8 0.0 0.8 0.1 0.4 0.3 0.3 4.2 0.7 9.3 0.1 10.3 0.1 0.5 0.0 0.0 0.4 6.3 21.9 3.1 7.6 0.6 0.1 0.0 12.3 7.3 0.4 0.0 3.5 3.4 0.4 6.3 0.2 9.6 6.4 0.4 0.0 11.7 3.6 0.6 3.9 0.3 0.3 0.3 4.1 0.8 0.2 1.2 3.9 1.8 1.6 0.9 3.4 0.5 2.9 0.5 0.6 14.1 17.7 18.7 18.8 14.6 16.8 15.8 15.9 16.2 13.2 16.4 27.5 7.7 0.0 6.2 11.4 2.1 0.5 2.5 0.6 2.8 4.8 4.0 4.7 24.2 1.5 4.4 3.7 2.1 3.5 0.4 1.1 13.7 5.8 108.2 5.0 4.2 6.5 0.0 0.0 9.3 4.7 3.5 4.4 1.5 3.5 0.0 13.3 5.3 0.0 0.7 1.7 13.8 1.9 2.0 0.3 0.9 54.7 1.8 0.5 0.0 2.8 0.6 5.5 7.2 9.5 17.6 2.7 0.3 4.5 0.4 2.5 0.3 0.1 5.4 2.8 0.0 3.0 5.6 17.4 5.0 1.2 0.3 1.9 0.9 17.6 1.3 2.6 ZNF417 MGC34079 ENSG00000173480 "Zinc finger protein 417" Q8TAU3 19 57900296-57916610 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 57.4" "HPA042125, HPA043288, HPA056213" Uncertain Uncertain Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "HPA042125: AB_2677862, HPA043288: AB_2678410, HPA056213: AB_2683069" "unprognostic (2.48e-1)" "unprognostic (2.55e-1)" "unprognostic (1.28e-1)" "unprognostic (3.74e-2)" "unprognostic (8.93e-2)" "unprognostic (1.63e-2)" "unprognostic (1.85e-1)" "unprognostic (5.76e-2)" "unprognostic (2.59e-3)" "unprognostic (2.34e-1)" "unprognostic (7.65e-3)" "unprognostic (5.33e-2)" "unprognostic (7.63e-2)" "unprognostic (1.01e-1)" "unprognostic (1.93e-2)" "unprognostic (8.75e-2)" "prognostic favorable (3.48e-4)" 7.7 9.7 29.5 9.7 29.9 15.7 21.3 37.9 38.0 18.4 31.9 10.5 9.4 13.4 48.9 8.3 13.0 15.0 11.2 28.9 33.5 11.7 14.9 10.5 19.0 28.7 29.1 12.1 8.4 15.4 10.5 10.0 28.8 15.8 13.4 25.8 12.6 17.4 7.3 29.0 10.7 10.4 25.3 17.8 14.5 9.5 31.3 21.6 21.1 6.3 22.3 9.3 4.9 35.6 7.1 10.8 17.2 11.9 17.0 16.2 14.6 8.8 12.7 8.0 6.7 11.6 4.1 15.1 4.8 12.9 6.1 4.9 10.9 11.9 22.4 2.6 57.4 16.2 26.5 10.7 11.5 15.0 16.7 11.9 11.9 7.9 10.5 14.9 10.3 12.0 5.1 0.9 16.7 6.9 16.3 7.2 9.9 4.9 10.6 12.8 20.7 10.8 8.6 32.1 15.7 10.2 11.6 7.8 3.0 17.7 8.3 12.0 7.1 20.2 8.6 4.6 8.9 16.1 27.8 12.5 8.7 6.0 9.8 5.9 2.0 5.1 2.6 2.4 3.3 2.6 3.0 2.6 1.5 3.6 4.0 3.0 3.3 2.1 1.7 3.3 2.7 1.5 29.5 29.9 37.9 38.0 28.9 33.5 28.7 29.1 28.8 25.3 31.3 35.6 1.5 6.4 1.1 5.5 1.7 0.8 1.2 0.7 1.8 4.0 2.5 1.9 3.0 2.8 4.8 0.0 0.0 1.0 1.5 1.7 0.0 1.2 0.5 1.2 1.2 2.6 6.0 6.1 3.9 1.4 0.8 2.0 2.0 1.6 4.5 2.0 2.9 2.2 1.0 1.7 3.8 2.1 0.0 2.5 1.5 0.1 2.5 1.7 0.0 1.9 1.0 0.9 2.1 2.5 5.7 0.4 0.5 1.5 5.0 1.4 1.5 1.5 2.2 3.9 6.6 1.9 1.7 1.3 2.1 1.0 1.3 0.8 2.0 1.2 1.7 1.6 ZNF419 "ZAPHIR, ZNF419A" ENSG00000105136 "Zinc finger protein 419" Q96HQ0 19 57487711-57496098 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 31.9" "HPA003152, HPA003274" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA003152: AB_1080716, HPA003274: AB_1080714" "unprognostic (3.50e-2)" "unprognostic (1.40e-5)" "unprognostic (1.12e-1)" "unprognostic (2.63e-2)" "unprognostic (2.55e-2)" "unprognostic (8.26e-2)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (3.18e-1)" "unprognostic (1.33e-1)" "unprognostic (8.55e-5)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.20e-1)" "unprognostic (2.42e-1)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.53e-5)" 6.0 8.7 10.0 4.6 10.1 3.0 6.2 10.7 12.6 4.8 9.9 6.3 3.8 5.3 9.7 4.7 6.2 3.5 8.2 10.0 10.1 8.1 6.6 7.0 7.4 9.4 8.9 7.8 4.6 9.1 13.4 6.1 8.8 8.9 3.6 11.1 6.4 6.3 10.4 7.4 6.2 4.0 8.9 10.6 5.3 5.3 10.2 8.0 10.8 7.8 8.9 5.4 4.6 10.1 5.4 6.0 10.3 10.5 4.7 7.1 8.9 6.4 8.8 5.8 31.9 3.8 3.4 1.8 5.1 4.5 5.2 1.6 4.9 13.3 8.0 0.5 22.4 8.3 9.1 4.2 16.8 6.5 6.0 9.7 19.3 5.8 13.8 12.0 6.4 8.0 0.9 1.3 7.3 0.9 10.9 6.7 6.8 0.7 7.9 10.1 9.9 7.6 6.3 11.5 8.4 9.4 6.5 6.0 6.2 8.8 5.3 9.7 6.6 7.0 7.7 2.5 5.6 15.2 18.0 4.5 5.6 3.5 5.7 4.5 2.7 6.1 5.2 3.3 8.9 14.3 8.9 6.6 4.7 15.8 13.8 7.4 3.2 9.7 2.7 3.4 6.5 4.4 10.0 10.1 10.7 12.6 10.0 10.1 9.4 8.9 8.8 8.9 10.2 10.1 3.1 0.0 5.3 3.6 7.2 4.1 5.7 4.9 2.8 8.1 4.3 5.2 5.3 4.3 5.2 7.3 6.2 5.0 4.2 1.3 0.0 5.8 0.3 2.0 2.1 4.8 1.2 2.5 3.3 1.8 2.4 3.7 0.5 1.7 4.5 7.4 5.7 4.6 3.2 10.1 2.8 1.8 8.2 3.2 1.7 0.5 1.8 1.8 5.4 0.0 4.1 6.8 7.2 3.5 1.9 2.5 2.8 5.7 1.6 9.0 2.0 1.9 1.8 9.5 6.6 2.9 3.3 4.9 10.4 2.1 3.8 8.3 4.8 4.2 1.8 5.6 ZNF428 "C19orf37, MGC51082, Zfp428" ENSG00000131116 "Zinc finger protein 428" Q96B54 19 43607224-43619629 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042596, HPA048072" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "HPA042596: AB_2678070, HPA048072: AB_2680249" "unprognostic (2.45e-3)" "unprognostic (5.51e-2)" "unprognostic (6.68e-3)" "unprognostic (6.31e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (3.22e-2)" "unprognostic (2.32e-2)" "unprognostic (2.53e-1)" "unprognostic (6.67e-2)" "prognostic favorable (3.60e-5)" "unprognostic (3.85e-1)" "unprognostic (5.59e-2)" "unprognostic (1.85e-1)" "unprognostic (2.30e-2)" "unprognostic (4.00e-1)" "unprognostic (2.74e-2)" 26.4 43.4 47.5 17.3 45.6 24.0 26.7 39.3 59.8 38.5 28.9 48.8 17.3 43.4 8.9 22.3 34.7 10.7 45.7 46.9 44.9 44.4 39.2 25.2 17.6 44.7 43.9 43.3 30.7 18.1 55.2 13.5 39.0 41.7 6.3 15.6 28.2 14.0 44.1 18.8 25.0 10.7 40.3 30.9 30.1 57.1 52.2 22.0 37.5 14.3 10.0 34.1 26.7 44.6 38.2 33.8 53.2 79.6 20.8 15.5 21.6 28.6 15.6 23.0 24.5 19.8 25.6 66.3 62.7 26.1 13.8 9.4 21.7 6.1 7.8 54.1 87.2 73.4 34.1 34.7 39.0 57.3 55.8 27.8 12.7 19.9 10.3 23.3 32.5 48.3 76.9 40.1 24.6 42.3 140.0 97.9 30.8 17.9 22.8 135.6 23.3 49.1 27.3 25.4 90.2 102.0 44.2 25.5 66.6 14.2 15.3 79.6 55.2 24.1 66.7 22.7 44.5 43.2 56.8 117.1 34.2 56.9 53.4 1.4 2.1 9.3 6.2 1.4 3.1 4.8 5.5 6.1 2.5 6.2 5.9 2.7 0.8 2.6 2.6 5.6 3.9 1.0 47.5 45.6 39.3 59.8 46.9 44.9 44.7 43.9 39.0 40.3 52.2 44.6 67.8 0.0 3.9 26.1 44.5 32.1 80.3 173.5 55.8 101.7 68.6 74.7 19.7 61.5 76.4 66.2 14.6 142.1 78.8 43.1 148.7 89.1 153.3 81.7 79.1 69.3 162.2 66.0 17.6 79.6 46.7 79.3 38.7 59.4 36.3 214.9 76.4 51.4 104.4 57.2 19.7 62.3 156.6 38.6 60.8 63.5 88.9 42.3 113.8 14.0 45.4 191.7 99.9 18.1 26.7 74.5 52.0 90.7 45.5 41.0 30.0 216.8 48.1 72.5 72.3 59.0 102.9 29.6 173.1 44.2 25.9 55.1 71.3 174.1 52.8 53.7 ZNF433 FLJ40981 ENSG00000197647 "Zinc finger protein 433" Q8N7K0 19 12014732-12035741 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 198.4;Late spermatids: 134.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA073724 Enhanced Approved "Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Nuclear bodies" "HPA073724: AB_2686631" "unprognostic (3.48e-2)" "unprognostic (1.24e-1)" "unprognostic (9.90e-2)" "unprognostic (6.84e-2)" "unprognostic (2.67e-1)" "unprognostic (3.92e-2)" "unprognostic (1.13e-1)" "unprognostic (4.16e-2)" "unprognostic (3.66e-3)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (1.36e-3)" "prognostic favorable (8.33e-15)" "unprognostic (1.06e-2)" "unprognostic (6.95e-2)" "unprognostic (9.20e-2)" "unprognostic (2.69e-2)" 4.1 3.8 5.1 2.3 5.2 11.8 7.8 10.9 5.2 5.7 5.3 3.6 2.1 4.9 9.4 6.9 4.7 3.8 5.3 6.1 5.2 14.2 5.3 4.0 3.2 5.2 5.4 5.7 9.2 9.1 4.9 5.1 5.0 6.3 3.6 9.9 7.2 4.7 5.6 9.0 2.5 3.2 4.3 4.6 4.8 27.6 5.1 1.8 9.1 3.9 2.9 4.5 5.3 6.0 5.5 0.4 4.1 11.5 3.9 3.7 6.0 4.8 3.5 5.3 5.6 3.1 1.1 1.7 2.6 4.1 3.6 2.2 0.0 5.3 5.0 0.8 1.4 4.0 1.1 3.4 4.1 3.7 9.0 4.3 4.9 3.7 1.8 3.3 0.0 6.4 1.0 0.8 5.9 2.3 4.9 4.7 1.6 0.1 4.5 2.6 2.8 0.4 7.7 11.3 3.4 2.8 0.0 3.0 2.3 4.4 6.2 5.5 3.4 6.0 2.5 10.3 3.4 8.1 10.6 4.8 1.1 4.2 3.7 6.5 1.1 5.1 1.3 0.9 1.1 1.5 1.2 1.7 4.1 2.6 1.8 2.2 2.0 5.9 1.4 3.9 0.9 1.1 5.1 5.2 10.9 5.2 6.1 5.2 5.2 5.4 5.0 4.3 5.1 6.0 3.8 3.2 2.8 7.5 1.7 1.8 3.4 3.7 1.8 4.9 4.8 4.3 7.2 5.7 4.1 5.5 16.7 10.5 1.7 0.8 7.9 4.2 198.4 7.1 3.8 2.2 0.0 3.6 6.7 3.8 4.5 3.1 3.6 9.5 3.8 3.3 1.4 3.1 6.9 6.7 5.9 0.5 4.1 2.2 1.6 134.4 3.1 1.5 5.4 0.0 0.0 4.7 1.0 10.1 3.7 3.0 1.1 4.1 0.6 2.1 0.0 6.1 6.1 8.1 6.6 1.9 2.9 35.1 5.7 4.5 2.6 3.4 0.9 2.4 0.8 2.5 ZNF438 bA330O11.1 ENSG00000183621 "Zinc finger protein 438" Q7Z4V0 10 30820207-31031937 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 111.3;Excitatory neurons: 55.3;Inhibitory neurons: 74.7;Microglial cells: 76.8;Oligodendrocyte precursor cells: 137.2;Oligodendrocytes: 86.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 19.0;U-937: 25.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039843 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "HPA039843: AB_10795159" "unprognostic (1.69e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" "unprognostic (9.21e-2)" "unprognostic (4.75e-2)" "unprognostic (1.22e-2)" "unprognostic (3.98e-3)" "unprognostic (1.30e-1)" "unprognostic (4.65e-1)" "unprognostic (2.33e-1)" "unprognostic (2.11e-2)" "unprognostic (4.85e-2)" "unprognostic (1.08e-2)" "unprognostic (9.96e-2)" "unprognostic (1.52e-1)" "unprognostic (8.52e-3)" "unprognostic (9.50e-2)" 11.9 3.6 5.5 6.4 5.7 5.5 7.4 5.1 7.3 8.5 5.7 11.3 3.8 9.2 6.6 4.6 8.2 5.6 11.0 5.6 5.8 4.4 5.4 8.4 4.0 5.3 5.2 5.9 3.1 3.7 4.9 4.0 5.5 5.4 4.1 4.5 6.2 5.6 24.6 6.8 5.3 8.7 5.3 10.3 6.0 8.4 6.3 7.8 9.7 17.4 3.1 9.3 6.8 6.5 3.7 3.7 3.1 2.7 18.0 12.5 1.7 2.9 4.2 4.5 5.6 0.2 4.4 5.0 3.3 5.2 4.2 1.0 1.6 2.2 6.3 11.6 1.2 2.2 2.0 0.2 10.1 1.7 2.3 6.0 3.7 6.4 3.6 4.1 19.0 5.8 4.3 3.5 6.2 2.7 5.9 9.7 0.3 2.7 1.5 2.6 4.5 2.9 6.4 0.9 2.3 2.5 1.4 0.6 2.1 2.0 1.4 16.2 7.9 2.0 3.5 6.1 3.6 0.8 1.5 0.1 4.0 25.3 1.5 1.3 7.2 3.3 2.0 6.9 1.5 1.0 1.5 2.7 2.2 3.7 3.1 1.7 13.1 3.9 4.3 2.8 3.6 3.5 5.5 5.7 5.1 7.3 5.6 5.8 5.3 5.2 5.5 5.3 6.3 6.5 7.8 3.2 4.8 111.3 3.2 1.0 2.0 1.7 5.2 5.5 2.1 2.2 13.0 5.7 4.2 3.7 6.2 3.5 2.0 1.8 7.9 3.6 25.2 2.7 5.6 6.1 0.0 2.5 55.3 4.2 4.6 9.1 7.1 2.4 12.6 4.1 6.4 1.8 6.9 3.3 74.7 2.6 0.0 12.9 3.5 9.6 4.1 36.3 0.0 76.8 7.3 2.4 7.2 137.2 86.9 3.7 0.8 8.2 3.6 1.3 2.5 3.9 3.9 5.3 6.6 17.0 6.7 12.8 8.0 6.0 2.4 1.6 4.2 2.4 2.3 1.8 ZNF439 DKFZp571K0837 ENSG00000171291 "Zinc finger protein 439" Q8NDP4 19 11848726-11883750 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 52.1;Rod photoreceptor cells: 49.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 26.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 15.4;U-138 MG: 15.6" HPA047845 Approved Uncertain Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA047845: AB_2680178" "unprognostic (1.56e-1)" "unprognostic (2.56e-3)" "unprognostic (4.83e-2)" "unprognostic (3.55e-3)" "unprognostic (2.93e-2)" "unprognostic (1.19e-3)" "unprognostic (8.26e-3)" "unprognostic (7.54e-2)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "unprognostic (9.66e-4)" "unprognostic (1.00e-1)" "unprognostic (8.68e-2)" "unprognostic (2.40e-1)" "unprognostic (8.19e-2)" "unprognostic (4.94e-2)" "unprognostic (1.29e-2)" 2.6 3.5 3.8 3.5 4.7 4.2 5.7 8.2 5.2 4.2 4.3 5.0 1.1 5.2 5.0 3.2 4.0 2.4 3.5 4.0 4.0 6.3 1.3 5.1 7.3 4.5 4.1 8.1 4.1 16.5 10.1 5.2 5.0 6.2 3.8 14.7 5.3 4.4 0.8 8.0 8.0 2.6 4.0 9.4 3.9 5.7 4.1 10.0 7.3 1.1 7.6 5.6 4.8 6.7 0.1 0.0 4.2 12.2 0.4 0.3 0.0 5.2 1.8 6.2 4.2 3.0 0.2 4.5 2.2 2.9 1.8 0.1 0.0 0.4 7.2 0.0 0.1 4.4 0.0 1.8 1.2 0.0 4.2 1.2 0.3 1.3 0.0 2.7 0.0 4.2 0.8 0.0 0.4 0.4 6.2 15.4 5.1 0.0 1.2 7.3 1.2 0.0 4.6 2.6 7.5 8.0 0.0 0.1 5.6 4.3 3.2 10.0 0.0 15.6 1.4 1.3 3.1 6.0 10.1 10.1 0.2 0.0 4.3 26.1 0.6 5.7 1.7 1.6 2.3 8.9 3.0 1.7 2.8 8.6 5.4 3.1 1.6 2.2 3.5 2.7 1.4 1.9 3.8 4.7 8.2 5.2 4.0 4.0 4.5 4.1 5.0 4.0 4.1 6.7 3.1 3.2 10.4 15.0 23.9 0.5 2.5 1.6 3.4 26.2 3.9 4.6 3.5 11.5 6.8 0.0 52.1 32.8 8.3 9.2 3.9 8.2 4.5 6.5 5.1 4.6 6.1 3.0 19.2 1.8 22.2 3.8 4.1 4.4 29.8 11.2 6.1 0.2 4.2 16.8 8.7 2.3 2.0 1.9 3.1 3.8 4.4 2.7 5.4 14.0 2.4 10.4 25.7 31.7 28.3 3.0 6.0 7.9 4.1 2.1 6.5 2.1 5.8 49.9 13.1 1.8 5.9 21.7 5.8 1.1 1.8 13.5 7.4 2.8 3.1 1.3 ZNF449 "FLJ23614, ZSCAN19" ENSG00000173275 "Zinc finger protein 449" Q6P9G9 X 135344796-135363413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 15.8;Inhibitory neurons: 12.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018079 Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA018079: AB_1859277" "unprognostic (5.51e-3)" "unprognostic (1.64e-1)" "unprognostic (6.94e-2)" "unprognostic (2.74e-1)" "unprognostic (1.30e-1)" "unprognostic (2.20e-1)" "unprognostic (3.74e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-2)" "unprognostic (4.86e-2)" "unprognostic (2.69e-1)" "unprognostic (5.31e-2)" "unprognostic (1.34e-3)" "unprognostic (1.28e-1)" "unprognostic (2.54e-1)" "unprognostic (9.61e-2)" "unprognostic (4.22e-2)" 7.3 10.3 2.9 4.4 3.2 1.4 6.1 2.6 4.0 5.6 2.7 5.5 3.2 6.4 5.3 3.6 4.4 5.3 5.3 3.2 3.4 3.8 3.5 5.0 3.9 3.2 2.9 4.5 8.3 5.8 4.2 6.8 3.1 5.6 3.4 4.9 4.8 4.3 5.2 3.6 3.7 4.8 2.8 6.1 4.9 2.8 3.8 2.8 7.0 5.5 3.4 4.5 4.7 3.1 2.7 3.8 7.7 6.3 6.8 13.5 3.7 5.1 3.9 3.2 7.8 1.3 3.6 1.7 6.4 4.0 4.3 3.1 5.4 2.3 5.1 2.3 4.6 2.2 4.3 2.0 5.2 1.8 3.2 5.3 6.6 2.7 7.9 4.5 6.2 4.2 2.2 1.8 9.2 1.5 2.3 2.0 2.7 2.6 4.2 1.9 5.1 2.5 4.7 1.6 1.8 4.5 1.2 3.7 3.8 4.9 2.7 2.0 6.1 7.4 2.7 5.0 4.6 1.4 1.8 1.3 2.9 3.0 4.8 0.7 1.2 1.7 1.2 1.5 2.4 0.7 1.1 1.7 1.1 0.4 1.1 1.1 0.3 2.6 3.3 0.7 1.1 1.0 2.9 3.2 2.6 4.0 3.2 3.4 3.2 2.9 3.1 2.8 3.8 3.1 6.7 0.0 2.2 7.8 2.4 0.9 0.9 1.1 1.2 6.0 2.5 2.5 10.2 1.5 1.3 1.8 0.0 2.5 1.3 0.8 0.0 1.7 0.3 1.2 3.4 6.4 3.0 0.8 15.8 0.6 2.1 3.7 3.1 1.1 1.3 6.4 6.8 0.6 4.2 10.1 12.5 0.8 0.0 3.2 1.9 0.5 5.3 2.4 3.6 8.4 5.0 3.9 0.0 9.5 7.2 1.2 1.4 4.1 1.1 1.1 0.6 0.6 2.2 2.8 0.0 2.4 4.0 2.8 2.3 1.0 2.3 1.2 1.9 11.5 0.6 0.6 ZNF462 "DKFZP762N2316, KIAA1803, Zfp462" ENSG00000148143 "Zinc finger protein 462" Q96JM2 9 106863166-107013634 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 114.9;Oligodendrocyte precursor cells: 486.5;Oligodendrocytes: 152.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022283 Uncertain Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA022283: AB_2220602" "unprognostic (4.22e-2)" "unprognostic (3.89e-2)" "unprognostic (2.60e-2)" "unprognostic (1.25e-2)" "unprognostic (1.99e-1)" "unprognostic (2.28e-1)" "unprognostic (2.04e-2)" "unprognostic (2.01e-1)" "unprognostic (3.62e-2)" "unprognostic (1.84e-2)" "unprognostic (2.16e-1)" "unprognostic (6.04e-2)" "prognostic favorable (6.19e-4)" "unprognostic (2.96e-2)" "unprognostic (1.68e-1)" "unprognostic (9.00e-2)" "unprognostic (1.33e-2)" 3.4 8.4 10.6 1.9 16.6 0.1 3.8 13.9 14.2 8.0 6.2 4.9 1.0 4.2 1.8 7.8 5.2 2.9 5.8 8.6 16.4 3.9 1.6 3.0 0.8 14.7 16.0 7.4 1.1 6.1 4.1 3.1 17.6 6.8 3.8 8.2 7.7 4.1 13.2 6.7 2.2 6.7 10.0 2.9 1.7 5.9 16.0 2.0 7.2 5.8 1.3 3.9 6.2 15.9 4.8 12.6 22.5 14.0 6.9 4.9 3.2 3.2 4.0 2.8 3.0 14.8 5.7 0.1 8.3 2.9 13.8 7.6 14.9 12.4 3.5 0.1 2.1 0.0 5.3 0.1 2.6 3.4 0.4 4.6 6.0 6.8 18.0 7.4 1.3 6.0 0.0 6.7 7.3 8.2 2.7 0.1 16.0 0.0 10.0 0.0 15.4 0.3 7.8 4.4 10.6 12.3 6.3 0.1 4.7 13.7 11.2 0.1 1.3 3.8 13.2 8.1 9.8 0.0 0.1 0.1 5.8 0.3 13.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 10.6 16.6 13.9 14.2 8.6 16.4 14.7 16.0 17.6 10.0 16.0 15.9 25.6 22.4 29.1 114.9 0.9 33.6 10.8 10.6 44.9 60.7 21.6 18.7 27.7 25.8 10.3 7.3 31.3 14.4 0.2 14.7 5.9 7.9 63.1 7.6 25.5 23.3 16.8 2.1 18.4 2.6 7.3 14.1 4.1 10.1 17.1 18.7 40.4 0.0 1.8 18.5 91.6 15.5 12.2 0.8 4.2 16.8 14.6 1.3 12.4 15.9 2.0 19.8 0.0 486.5 152.2 7.7 5.3 27.1 0.0 15.1 6.3 17.4 15.2 39.4 26.3 21.5 22.1 1.3 24.7 24.0 11.5 3.1 1.1 22.0 17.5 6.6 ZNF488 FLJ32104 ENSG00000265763 "Zinc finger protein 488" Q96MN9 10 47365496-47384293 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 34.4;intestine: 22.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 7.0;Oligodendrocyte precursor cells: 10.1;Oligodendrocytes: 20.1;Proximal enterocytes: 21.5;Syncytiotrophoblasts: 36.1" "Cancer enhanced" "Detected in many" "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 46.9;HDLM-2: 70.1;RT4: 38.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035957, HPA035958" Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 45: Intestine - Brush border" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Cytosol" "HPA035957: AB_10672234, HPA035958: AB_2674887" "unprognostic (3.29e-2)" "unprognostic (1.05e-2)" "unprognostic (7.87e-2)" "unprognostic (1.49e-4)" "unprognostic (1.16e-1)" "unprognostic (8.85e-2)" "unprognostic (1.60e-3)" "unprognostic (2.13e-2)" "unprognostic (3.11e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (4.02e-7)" "unprognostic (3.60e-1)" "unprognostic (6.62e-5)" "unprognostic (2.76e-1)" "unprognostic (4.47e-1)" "unprognostic (8.10e-2)" "unprognostic (3.18e-2)" 0.2 0.1 10.2 0.1 22.2 0.0 0.8 23.6 18.1 0.3 3.1 0.6 22.4 0.1 1.6 0.9 0.1 0.2 0.1 18.0 14.8 1.1 0.0 0.2 0.0 29.4 26.4 0.3 0.0 0.0 0.8 3.4 26.8 0.3 0.6 2.6 0.4 0.1 0.0 1.7 11.2 0.1 20.4 0.0 0.3 0.8 23.2 0.3 0.1 0.1 0.6 0.5 0.5 34.4 4.9 13.7 2.3 0.7 0.0 0.0 0.2 0.5 0.6 0.8 0.8 5.3 12.7 0.3 0.8 0.0 5.3 46.9 1.2 5.2 0.7 70.1 1.4 0.2 1.5 0.4 0.0 0.1 0.7 0.0 12.2 0.5 1.3 0.2 0.0 2.7 0.0 0.0 0.0 0.2 0.5 0.2 3.5 10.3 1.3 0.0 5.8 0.0 0.3 38.2 11.1 2.0 3.3 0.5 0.0 5.1 1.1 0.1 0.0 0.0 3.5 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 22.2 23.6 18.1 18.0 14.8 29.4 26.4 26.8 20.4 23.2 34.4 0.2 0.0 0.0 1.0 0.0 0.6 0.9 0.4 0.0 1.8 0.2 0.4 0.6 0.0 0.2 0.0 0.0 7.0 0.0 0.8 5.9 0.2 0.0 0.1 0.0 0.1 0.0 0.0 1.9 0.2 0.5 0.3 0.0 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 10.1 20.1 0.6 0.0 0.0 0.0 1.1 21.5 0.2 0.0 0.5 0.0 0.2 0.6 0.1 1.5 0.0 0.1 36.1 0.0 0.1 1.5 0.4 ZNF511 "MGC30006, Zfp511" ENSG00000198546 "Zinc finger protein 511" Q8NB15 10 133308914-133313162 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035360 Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" "Intracellular and membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA035360: AB_10601931" "unprognostic (3.35e-2)" "unprognostic (2.19e-1)" "unprognostic (1.91e-1)" "unprognostic (8.84e-2)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (3.04e-1)" "unprognostic (1.68e-2)" "unprognostic (2.75e-1)" "unprognostic (1.64e-2)" "unprognostic (1.40e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.94e-2)" "unprognostic (3.91e-2)" "unprognostic (2.55e-1)" "unprognostic (4.52e-2)" 12.7 11.6 15.9 8.7 16.2 17.1 11.3 15.5 17.2 15.8 17.5 19.7 16.1 15.7 10.7 10.8 15.4 9.4 21.2 15.4 15.4 10.4 21.3 11.4 12.6 16.7 15.9 20.4 15.5 14.7 12.7 8.7 15.7 16.1 12.8 5.8 16.7 10.7 49.1 7.9 13.2 11.1 16.4 12.5 12.5 9.6 16.8 11.4 10.9 31.9 9.7 13.6 12.5 16.5 54.1 54.0 30.3 43.8 25.6 21.6 32.6 25.2 39.3 53.3 44.4 88.0 50.9 48.2 24.4 29.5 33.9 48.8 41.9 36.0 23.2 38.8 92.1 29.1 22.1 53.4 21.0 57.5 52.1 22.0 19.2 43.7 26.5 30.6 24.3 22.7 40.0 22.4 18.6 71.2 27.5 76.1 37.3 50.2 74.6 37.1 37.1 12.4 28.3 18.6 16.9 37.0 16.8 30.0 38.2 18.7 23.2 33.1 23.3 23.1 35.4 26.5 68.5 31.3 36.4 66.1 37.5 26.8 12.9 40.2 61.1 68.6 45.4 52.6 35.6 66.6 37.0 46.6 61.0 51.8 41.6 40.8 8.5 41.0 51.1 65.9 36.2 47.3 15.9 16.2 15.5 17.2 15.4 15.4 16.7 15.9 15.7 16.4 16.8 16.5 16.3 16.0 14.5 7.5 33.6 29.6 45.6 40.7 39.3 19.5 37.3 52.6 23.6 25.8 21.9 22.0 8.4 61.2 36.7 33.3 70.5 39.5 29.5 18.5 22.4 20.9 53.4 40.2 10.7 41.2 62.9 34.0 20.4 15.2 78.1 40.6 20.3 54.4 47.4 21.9 7.6 128.8 22.4 33.9 38.0 8.8 41.7 39.9 16.0 5.6 64.3 27.4 41.2 3.5 12.3 38.6 44.0 30.5 40.4 43.0 60.8 72.1 23.2 23.6 26.3 27.3 34.5 58.1 48.0 36.3 35.9 28.2 33.0 38.6 65.9 41.5 ZNF530 KIAA1508 ENSG00000183647 "Zinc finger protein 530" Q6P9A1 19 57599885-57612722 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 8.6;Muller glia cells: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HEK 293: 75.0;U-266/84: 58.8" HPA045868 Uncertain Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA045868: AB_2679478" "unprognostic (1.57e-1)" "unprognostic (3.02e-3)" "unprognostic (5.65e-2)" "unprognostic (2.90e-2)" "unprognostic (3.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.54e-2)" "unprognostic (6.80e-2)" "unprognostic (9.69e-3)" "unprognostic (4.98e-3)" "unprognostic (3.19e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (1.70e-1)" "unprognostic (3.11e-1)" "unprognostic (1.86e-2)" "unprognostic (1.06e-1)" 1.5 1.4 4.5 1.2 4.2 3.2 1.6 6.8 5.4 0.7 5.6 1.1 1.0 1.0 1.9 0.9 0.7 0.7 4.0 4.6 4.2 1.1 0.8 0.9 2.0 4.3 3.7 0.9 1.5 0.8 0.7 1.2 4.0 1.4 0.8 2.6 1.2 1.4 6.3 2.2 1.0 0.7 3.8 2.2 1.8 1.2 4.0 2.3 1.0 2.7 2.3 1.0 0.7 4.8 6.7 5.8 4.3 3.7 0.3 1.9 6.8 4.1 1.7 6.8 3.8 4.1 1.0 0.8 3.3 1.5 4.1 2.2 3.6 3.0 7.2 0.2 75.0 13.4 11.6 2.6 0.5 4.9 6.1 1.3 1.7 6.4 1.8 1.9 1.5 4.7 1.7 3.0 2.3 2.6 7.0 3.8 6.4 0.5 14.2 0.9 13.6 6.3 1.3 11.3 4.9 4.5 4.8 1.2 1.4 3.8 3.1 7.6 2.0 8.5 5.3 1.9 8.5 14.6 58.8 9.3 5.2 5.2 6.0 1.0 1.5 1.0 3.0 0.9 2.2 3.5 2.0 3.1 1.8 2.5 2.7 2.2 1.7 3.1 1.1 1.7 2.9 1.6 4.5 4.2 6.8 5.4 4.6 4.2 4.3 3.7 4.0 3.8 4.0 4.8 2.7 6.4 1.5 1.6 2.3 1.8 0.7 1.7 1.8 3.3 1.8 1.0 8.6 1.5 0.9 0.0 0.0 2.0 3.1 0.6 1.9 1.9 0.3 0.9 0.8 2.7 0.0 4.0 1.4 2.9 1.5 1.4 1.1 0.8 2.5 2.2 2.9 0.7 2.0 0.0 1.0 0.2 2.0 0.8 2.0 0.3 0.9 0.6 5.4 0.0 1.5 9.1 2.1 0.5 0.9 1.4 1.7 1.5 2.5 1.3 0.9 0.8 0.7 4.2 6.6 1.5 1.7 2.1 2.9 1.6 1.7 1.4 2.3 1.1 1.0 0.9 ZNF557 MGC4054 ENSG00000130544 "Zinc finger protein 557" Q8N988 19 7069703-7087968 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA003151, HPA029291" Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Intermediate filaments" "HPA003151: AB_1859344, HPA029291: AB_10602357" "unprognostic (1.05e-1)" "unprognostic (2.96e-3)" "unprognostic (5.29e-2)" "prognostic favorable (5.70e-4)" "unprognostic (2.56e-2)" "prognostic favorable (3.67e-6)" "unprognostic (1.32e-1)" "prognostic favorable (2.62e-4)" "unprognostic (2.51e-2)" "unprognostic (2.51e-2)" "prognostic favorable (1.51e-4)" "unprognostic (2.28e-1)" "unprognostic (2.24e-2)" "unprognostic (1.52e-3)" "unprognostic (4.71e-2)" "unprognostic (6.18e-2)" "unprognostic (2.81e-3)" 1.5 1.9 1.2 1.8 1.5 3.9 1.9 3.1 1.7 1.6 1.5 1.5 1.1 1.7 1.6 1.7 1.9 1.3 1.2 1.3 1.0 1.8 2.2 1.4 2.6 1.4 1.1 2.4 1.8 1.7 1.5 1.5 1.5 1.5 1.4 1.9 1.4 1.4 1.4 2.0 1.7 1.6 0.9 2.3 1.8 2.1 1.4 2.4 2.1 1.0 2.5 1.6 1.5 3.1 2.1 2.2 2.3 5.0 3.1 2.1 1.9 2.1 2.2 2.3 2.8 2.8 1.3 4.4 3.6 2.3 1.8 2.9 4.0 2.3 2.3 4.0 2.6 5.6 4.7 1.5 2.1 6.0 5.9 3.0 2.3 2.4 3.7 2.3 2.0 3.8 2.2 6.7 3.1 3.0 5.0 2.1 2.2 2.0 3.0 3.6 3.6 2.4 1.7 4.9 2.7 3.2 3.1 2.4 2.3 2.0 1.9 3.1 3.9 2.2 1.7 5.0 2.3 6.8 5.8 3.9 2.4 3.1 2.0 5.6 3.1 3.8 4.6 2.9 4.7 4.1 5.0 4.0 3.1 5.4 5.8 4.9 3.5 5.9 2.7 5.7 4.3 1.7 1.2 1.5 3.1 1.7 1.3 1.0 1.4 1.1 1.5 0.9 1.4 3.1 5.5 3.2 4.4 5.2 8.3 1.5 6.9 2.7 2.2 9.4 6.1 5.8 5.4 7.2 6.1 7.3 0.0 5.9 5.8 5.4 15.6 6.2 0.9 3.4 8.9 6.9 5.4 6.1 9.2 6.2 4.2 5.6 4.6 4.6 8.2 9.4 8.6 3.8 6.1 16.8 8.9 5.8 2.0 9.8 2.9 0.5 4.4 6.0 0.0 5.6 9.0 6.1 14.4 3.5 8.8 6.1 6.2 5.7 5.9 6.8 6.1 8.1 4.3 6.8 0.0 7.8 6.7 23.2 19.9 3.6 1.3 5.7 7.7 6.7 5.5 6.9 ZNF558 FLJ30932 ENSG00000167785 "Zinc finger protein 558" Q96NG5 19 8806170-8832314 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003151 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "HPA003151: AB_1859344" "unprognostic (2.54e-2)" "unprognostic (1.81e-1)" "unprognostic (1.90e-1)" "unprognostic (2.09e-2)" "unprognostic (1.84e-1)" "prognostic favorable (1.04e-4)" "unprognostic (1.61e-2)" "unprognostic (1.58e-2)" "unprognostic (1.69e-2)" "unprognostic (1.09e-2)" "unprognostic (3.20e-1)" "unprognostic (5.89e-3)" "prognostic unfavorable (1.23e-6)" "unprognostic (2.28e-2)" "unprognostic (6.92e-2)" "unprognostic (1.09e-1)" "prognostic favorable (9.30e-5)" 9.3 10.1 7.8 6.5 8.0 4.6 9.5 8.6 9.3 15.0 8.3 11.2 6.0 13.6 9.4 7.9 14.7 5.4 6.6 7.6 8.1 11.4 11.0 8.3 7.3 8.3 8.2 15.1 11.5 10.3 8.5 5.5 8.1 11.5 8.0 14.5 8.3 8.7 6.9 10.1 9.2 10.3 8.0 9.7 9.5 6.2 8.3 7.9 12.2 6.6 8.0 9.9 10.7 8.6 8.1 2.8 12.8 17.6 11.8 13.2 10.9 5.6 8.5 8.2 12.8 4.1 4.9 4.0 14.5 6.4 10.0 7.2 10.9 0.8 11.5 9.6 0.5 0.3 5.0 2.1 9.4 5.9 9.3 12.7 18.5 5.2 0.0 20.0 0.0 12.3 8.6 15.4 10.8 3.3 5.4 31.4 8.0 3.0 4.0 2.8 10.1 3.5 15.2 8.9 2.7 12.7 6.5 3.7 11.5 15.0 7.9 8.5 0.1 10.4 5.9 16.5 6.7 7.0 6.4 8.8 2.4 5.8 3.5 0.4 0.6 0.3 1.0 0.6 0.8 0.3 0.7 1.1 0.7 1.0 1.2 1.5 0.7 2.0 0.5 1.0 0.5 0.5 7.8 8.0 8.6 9.3 7.6 8.1 8.3 8.2 8.1 8.0 8.3 8.6 3.8 9.6 5.6 8.1 3.2 3.6 2.9 3.1 9.1 4.8 5.5 5.5 3.6 2.8 5.5 3.7 8.4 4.0 3.9 3.6 1.9 4.5 9.6 4.5 9.3 4.0 1.2 4.0 4.0 3.3 3.7 4.6 11.2 5.0 3.8 5.1 2.9 5.3 2.9 8.4 3.3 3.3 0.0 4.7 1.3 5.2 2.1 2.9 0.0 3.7 2.4 5.9 5.2 5.5 7.9 4.2 2.7 2.6 1.8 3.3 2.8 1.9 3.6 8.6 0.0 5.2 4.8 4.1 3.9 5.4 2.7 1.5 3.9 2.8 3.9 1.5 ZNF570 FLJ30791 ENSG00000171827 "Zinc finger protein 570" Q96NI8 19 37467585-37488652 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 56.0;Horizontal cells: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028881 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA028881: AB_10603938" "unprognostic (2.93e-2)" "unprognostic (1.55e-1)" "unprognostic (3.71e-2)" "unprognostic (1.24e-1)" "unprognostic (1.70e-2)" "unprognostic (1.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.23e-1)" "unprognostic (2.01e-2)" "unprognostic (1.12e-1)" "unprognostic (6.54e-2)" "unprognostic (4.59e-2)" "prognostic favorable (4.06e-5)" "unprognostic (5.30e-2)" "unprognostic (2.85e-2)" "unprognostic (3.12e-2)" "unprognostic (2.20e-3)" 2.1 2.4 2.4 1.7 2.9 2.2 2.9 3.3 3.0 2.1 1.8 1.6 1.9 2.5 2.1 2.3 2.0 2.2 2.5 2.5 3.0 2.8 1.8 2.0 2.7 2.8 3.0 3.4 1.6 4.0 1.8 2.1 2.7 2.9 1.2 3.1 2.3 2.1 2.0 1.8 1.5 2.3 2.7 2.4 2.1 6.0 2.7 2.4 3.2 2.8 2.4 1.9 1.3 3.4 1.5 2.0 2.7 8.3 3.6 4.4 1.3 2.9 1.5 2.7 3.6 0.0 0.6 0.3 3.9 2.1 1.6 0.3 2.4 1.8 3.2 1.6 1.7 2.0 0.2 0.9 2.5 0.1 4.2 3.8 1.7 1.8 0.0 2.5 2.6 3.2 0.3 0.1 2.9 0.5 4.8 1.5 1.7 0.1 0.8 0.8 2.8 1.6 2.2 2.3 2.5 5.2 0.0 0.0 1.0 3.3 1.6 2.2 1.4 1.1 2.1 1.8 2.1 4.4 4.2 2.1 0.0 0.2 2.2 0.7 0.7 0.9 1.3 1.3 1.0 1.6 2.1 0.9 0.7 1.4 1.7 1.8 1.4 1.8 0.5 0.7 1.3 0.9 2.4 2.9 3.3 3.0 2.5 3.0 2.8 3.0 2.7 2.7 2.7 3.4 7.9 6.4 0.5 1.6 5.5 1.7 1.7 0.7 4.6 6.4 5.7 6.0 13.7 5.7 2.8 1.8 10.4 2.6 11.4 1.3 9.8 5.5 56.0 6.5 6.6 7.4 6.0 3.0 2.1 3.8 6.7 6.7 1.1 3.9 6.3 5.7 8.2 2.2 3.3 32.0 2.0 1.7 0.0 2.5 0.7 9.0 5.0 3.5 5.4 0.0 2.5 5.4 8.2 2.5 2.9 2.9 1.1 9.8 2.6 1.8 1.6 3.6 3.4 7.2 0.0 6.7 7.6 11.0 6.6 4.8 0.4 1.4 7.9 4.4 2.1 1.1 ZNF678 MGC42493 ENSG00000181450 "Zinc finger protein 678" Q5SXM1 1 227563543-227677443 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 38.2;Oligodendrocytes: 44.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" HPA028507 Uncertain Approved Nucleoli,Mitochondria,Cytosol Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoli, Mitochondria, Cytosol" "HPA028507: AB_10603567" "unprognostic (1.76e-2)" "unprognostic (3.01e-2)" "unprognostic (1.68e-1)" "unprognostic (1.39e-1)" "unprognostic (1.20e-2)" "unprognostic (4.42e-3)" "unprognostic (3.92e-2)" "unprognostic (4.64e-2)" "unprognostic (1.59e-2)" "unprognostic (2.19e-2)" "unprognostic (2.50e-1)" "unprognostic (1.64e-1)" "unprognostic (3.54e-6)" "unprognostic (1.39e-1)" "unprognostic (4.18e-1)" "unprognostic (1.10e-1)" "unprognostic (4.88e-4)" 2.5 3.1 2.2 3.0 3.3 3.4 3.7 3.6 2.8 3.6 1.1 2.9 2.3 3.8 2.4 2.1 3.1 3.1 1.9 2.3 4.3 2.6 2.2 3.2 4.4 3.1 2.8 4.0 3.3 2.3 1.5 4.2 2.8 4.0 4.1 5.7 2.7 2.4 1.5 1.4 2.1 2.4 2.3 3.6 3.3 3.9 3.4 4.4 5.4 2.7 4.0 2.1 2.3 5.6 2.5 4.0 13.6 15.5 1.6 3.7 8.3 3.3 3.2 4.8 4.9 3.3 2.9 9.7 8.3 1.5 2.5 4.6 8.3 2.2 7.6 4.2 15.8 4.5 2.9 2.0 3.0 8.0 12.0 3.3 3.8 2.8 6.0 3.5 4.5 10.9 12.4 15.1 5.2 2.0 11.3 2.8 12.1 3.6 6.3 8.4 8.9 3.9 3.4 7.7 5.8 11.2 4.8 5.6 2.3 6.6 7.9 9.2 3.3 5.9 5.5 5.2 6.6 4.8 11.8 10.5 2.3 1.4 6.2 5.4 0.6 0.8 1.3 0.1 1.6 3.7 1.3 0.8 1.2 2.6 1.2 1.7 0.1 1.4 0.4 1.8 1.7 0.8 2.2 3.3 3.6 2.8 2.3 4.3 3.1 2.8 2.8 2.3 3.4 5.6 10.9 3.2 7.3 21.2 7.8 2.3 4.0 2.9 2.2 12.2 5.5 2.9 4.2 4.3 4.5 3.7 4.2 2.1 8.2 6.8 1.9 4.0 0.9 4.6 6.0 6.5 9.6 10.3 11.7 5.2 2.4 6.5 7.1 4.8 3.8 9.4 5.3 3.0 1.8 1.7 17.2 4.8 4.1 3.1 3.7 0.6 7.5 3.3 0.0 17.8 3.3 4.7 5.2 38.2 44.7 3.3 7.3 2.6 5.8 5.4 1.3 1.4 5.5 7.3 0.0 12.3 4.9 7.6 10.5 3.1 0.6 1.4 5.8 4.2 3.8 3.8 ZNF687 KIAA1441 ENSG00000143373 "Zinc finger protein 687" Q8N1G0 1 151281618-151292176 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.5" "Group enriched" "Detected in many" 8 "granulocytes: 13.5;monocytes: 4.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021193, HPA023948" Approved Enhanced Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA021193: AB_1859415, HPA023948: AB_2671380" "unprognostic (2.23e-1)" "unprognostic (3.25e-1)" "unprognostic (2.93e-2)" "unprognostic (9.64e-3)" "unprognostic (2.44e-2)" "unprognostic (7.82e-2)" "unprognostic (2.62e-2)" "unprognostic (1.56e-1)" "unprognostic (1.39e-1)" "unprognostic (9.91e-2)" "unprognostic (8.69e-3)" "unprognostic (2.10e-1)" "unprognostic (5.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.41e-1)" "unprognostic (8.54e-2)" "unprognostic (7.99e-2)" 8.5 10.9 9.0 8.2 9.9 31.2 8.7 12.6 10.2 9.9 6.9 10.7 8.6 10.5 5.5 11.0 9.7 7.0 8.9 8.5 8.4 10.2 9.7 8.6 10.1 10.5 9.6 11.7 16.0 14.1 13.0 7.1 9.5 11.3 5.7 9.4 12.0 8.6 10.9 12.3 11.3 6.1 8.9 14.4 10.8 14.5 9.7 9.3 10.8 6.9 7.5 10.4 8.7 10.5 14.8 21.5 20.4 12.6 11.3 9.5 26.3 7.6 12.9 13.8 13.1 18.1 19.6 12.6 18.7 12.3 14.7 22.3 18.1 15.2 6.1 17.3 18.3 11.9 18.8 20.1 12.1 14.3 16.7 14.7 15.3 11.6 12.1 12.3 9.4 13.4 19.5 22.6 7.8 44.8 19.2 16.8 27.6 19.8 16.5 16.9 16.1 22.8 11.6 22.1 18.5 27.7 20.8 24.6 19.7 19.2 32.2 30.1 9.2 11.0 12.1 13.9 11.6 26.2 24.1 31.3 14.0 9.4 14.2 0.5 1.8 13.5 0.5 2.3 0.5 1.0 0.5 0.4 0.9 1.1 0.7 0.8 8.8 0.4 4.5 0.8 0.4 1.2 9.0 9.9 12.6 10.2 8.5 8.4 10.5 9.6 9.5 8.9 9.7 10.5 4.3 3.2 4.6 3.6 5.8 4.7 2.8 4.9 5.7 6.7 6.0 5.5 1.4 10.0 3.5 1.8 10.4 6.7 3.8 9.3 3.9 5.5 3.1 4.3 3.7 4.4 2.4 3.0 1.6 6.0 5.3 4.2 7.7 5.3 0.0 8.5 2.9 4.5 5.3 8.4 1.9 5.6 8.2 5.2 4.1 2.8 6.2 5.8 0.0 2.8 6.0 5.2 5.2 3.0 1.7 7.3 3.5 7.2 5.8 4.7 10.2 4.1 3.4 10.8 13.1 4.4 3.9 6.9 6.8 4.3 3.4 9.4 4.3 6.5 7.3 5.1 ZNF691 Zfp691 ENSG00000164011 "Zinc finger protein 691" Q5VV52 1 42846573-42852477 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062527 Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nucleoli, Vesicles" "HPA062527: AB_2684791" "unprognostic (4.34e-2)" "unprognostic (4.05e-2)" "unprognostic (1.09e-1)" "unprognostic (4.32e-2)" "unprognostic (4.86e-2)" "unprognostic (5.50e-2)" "prognostic unfavorable (7.33e-6)" "unprognostic (1.40e-3)" "unprognostic (2.65e-3)" "unprognostic (5.12e-2)" "prognostic favorable (6.25e-5)" "unprognostic (1.24e-1)" "unprognostic (1.06e-2)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.00e-1)" "unprognostic (1.05e-1)" 5.9 9.8 11.0 8.8 11.9 2.3 11.2 11.4 14.4 11.1 11.7 9.7 6.5 9.9 15.1 6.1 9.9 6.1 9.1 10.6 11.7 11.6 18.2 7.3 13.0 12.3 11.5 13.0 8.9 13.6 9.2 9.3 12.1 10.5 7.2 11.3 9.8 11.0 8.0 9.5 7.5 9.5 11.1 12.1 7.7 6.7 12.3 15.5 12.1 9.9 12.7 9.0 7.0 12.6 6.6 9.1 18.1 15.0 16.0 12.2 2.3 7.7 9.3 12.4 12.3 6.5 9.5 16.2 11.8 7.3 6.2 11.5 17.6 10.3 10.6 29.3 17.8 17.0 27.2 11.7 11.9 6.6 3.5 10.6 12.3 15.6 12.7 15.1 12.8 15.8 16.8 6.9 12.3 5.3 19.8 8.7 27.1 7.2 6.8 13.2 22.8 11.2 11.6 6.2 13.0 12.9 7.9 14.2 13.3 26.9 7.8 22.2 6.7 12.3 12.8 7.0 8.6 16.5 14.0 4.7 8.6 7.8 10.6 24.5 12.7 19.2 12.9 11.5 17.0 17.2 17.4 17.8 12.7 23.4 16.8 16.6 6.9 21.3 12.4 14.1 23.1 14.8 11.0 11.9 11.4 14.4 10.6 11.7 12.3 11.5 12.1 11.1 12.3 12.6 3.6 6.4 2.7 2.6 4.1 1.8 2.7 4.1 2.8 2.5 4.5 5.6 6.5 10.0 2.7 5.5 4.2 6.5 1.4 1.4 7.9 5.5 6.8 1.2 3.3 5.1 3.0 3.0 2.0 3.8 5.3 4.3 3.1 1.2 5.1 5.3 5.0 7.6 6.8 1.7 2.3 2.8 6.1 4.1 1.2 3.2 7.2 3.0 1.8 3.7 3.1 6.4 5.2 5.0 4.1 2.3 3.2 7.2 2.3 3.2 3.5 9.6 3.2 4.2 0.0 2.3 3.2 10.4 7.4 3.1 0.9 3.3 3.3 5.3 2.4 1.2 ZNF696 FLJ14129 ENSG00000185730 "Zinc finger protein 696" Q9H7X3 8 143289676-143299952 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057855, HPA072473" Uncertain Approved Nucleoplasm,Nucleoli No No "Cluster 48: NK-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 9: U-2 OS - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm Nucleoli "HPA057855: AB_2683545, HPA072473: AB_2686524" "unprognostic (3.23e-2)" "prognostic unfavorable (6.63e-5)" "unprognostic (3.62e-2)" "prognostic unfavorable (3.52e-5)" "unprognostic (2.58e-1)" "unprognostic (7.86e-2)" "unprognostic (2.76e-3)" "unprognostic (8.82e-2)" "unprognostic (3.16e-1)" "unprognostic (3.02e-1)" "prognostic favorable (1.41e-4)" "unprognostic (6.57e-2)" "unprognostic (8.22e-2)" "unprognostic (7.99e-2)" "unprognostic (2.86e-1)" "unprognostic (3.42e-3)" "unprognostic (8.09e-3)" 4.0 3.3 3.9 3.3 3.7 3.5 3.2 5.9 6.1 3.4 0.0 3.3 6.0 4.5 2.5 2.6 3.4 2.1 2.8 4.2 2.5 3.3 4.6 2.8 3.8 5.6 3.0 4.7 5.0 4.3 3.2 2.7 5.0 3.1 1.9 3.6 5.7 2.3 3.9 6.6 3.7 2.3 0.9 4.0 3.3 3.5 3.4 2.1 3.7 2.4 3.0 3.7 2.8 4.9 8.2 7.4 7.8 8.8 3.2 2.5 14.9 6.3 2.4 4.4 2.7 4.3 6.3 0.7 8.2 2.5 2.5 5.8 8.5 3.8 4.5 9.1 17.9 10.8 8.8 6.7 3.4 4.5 13.5 2.4 6.1 3.0 6.8 3.3 2.2 6.4 22.2 5.3 3.1 17.3 4.6 8.8 10.2 9.7 17.1 9.8 4.4 8.1 3.0 6.3 11.6 16.1 9.3 6.7 8.2 5.3 10.3 8.1 4.5 6.2 13.4 5.5 10.9 9.7 7.3 10.0 4.2 9.2 7.5 1.2 2.0 1.7 2.9 1.1 3.0 2.4 2.1 3.1 2.1 3.2 3.9 3.5 1.2 3.5 2.0 3.8 0.7 1.9 3.9 3.7 5.9 6.1 4.2 2.5 5.6 3.0 5.0 0.9 3.4 4.9 2.2 0.0 0.0 3.6 3.0 2.9 2.3 0.6 0.0 5.3 1.5 1.3 2.8 2.8 0.3 3.7 6.2 1.7 1.8 2.1 3.9 2.4 1.2 0.8 2.3 2.5 0.0 1.3 3.4 2.0 1.8 1.9 2.0 1.0 0.0 2.9 2.2 2.2 1.2 3.3 3.9 1.0 2.0 0.9 0.7 2.4 4.1 0.7 1.8 1.0 0.9 1.8 6.2 4.5 3.1 1.5 0.3 1.2 2.3 1.7 2.7 1.9 0.3 4.5 6.6 1.7 2.2 3.0 5.7 1.1 2.0 0.4 2.5 2.7 2.0 0.6 ZNF710 "DKFZp547K1113, FLJ00306, FLJ37393" ENSG00000140548 "Zinc finger protein 710" Q8N1W2 15 90001324-90082206 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 44.2" "Cell type enhanced" "Detected in many" "Astrocytes: 38.8;Microglial cells: 149.9;Oligodendrocytes: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 5.7" "Group enriched" "Detected in many" 6 "dendritic cells: 1.4;granulocytes: 1.9;monocytes: 5.7" "Cell line enhanced" "Detected in all" "SK-BR-3: 44.8" "Low region specificity" "Detected in all" "HPA030226, HPA030227, HPA030228" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA030226: AB_2673384, HPA030227: AB_10599855, HPA030228: AB_10601899" "unprognostic (6.24e-2)" "unprognostic (7.07e-2)" "unprognostic (1.49e-2)" "unprognostic (2.40e-1)" "unprognostic (2.32e-1)" "unprognostic (1.36e-2)" "unprognostic (4.34e-2)" "unprognostic (8.45e-2)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" "unprognostic (9.86e-2)" "unprognostic (1.57e-1)" "unprognostic (2.91e-3)" "unprognostic (1.03e-2)" "unprognostic (3.24e-2)" "unprognostic (1.65e-2)" "unprognostic (8.65e-2)" 3.6 4.3 12.0 14.7 13.0 8.7 5.4 6.4 11.2 6.3 3.1 8.3 9.1 5.3 5.0 17.1 5.2 7.0 10.0 6.9 8.8 5.7 5.3 9.8 10.0 12.2 13.6 4.8 44.2 3.3 4.5 5.7 12.9 7.5 6.9 1.2 9.6 4.3 33.4 12.6 8.0 3.4 10.4 14.2 10.2 1.7 12.4 5.6 6.2 1.5 6.5 7.7 9.2 11.5 9.2 10.7 20.1 7.6 2.7 4.0 10.5 9.4 8.8 6.8 8.6 7.7 8.3 9.3 4.3 9.1 6.4 6.2 5.1 13.5 3.8 6.0 9.4 17.1 4.6 13.1 5.5 5.0 25.6 6.6 7.2 14.6 7.9 3.2 11.8 10.0 5.8 6.2 2.6 23.7 11.1 13.9 15.8 11.3 6.9 13.5 4.5 10.2 2.7 11.4 18.3 12.3 12.5 44.8 6.4 5.2 9.6 17.2 17.1 13.9 6.8 4.2 7.4 5.0 2.7 9.0 10.6 14.6 7.4 0.0 1.6 1.2 0.2 3.5 0.2 0.1 0.1 0.2 1.2 0.1 0.4 0.4 1.9 0.2 5.7 1.4 0.5 0.7 12.0 13.0 6.4 11.2 6.9 8.8 12.2 13.6 12.9 10.4 12.4 11.5 1.7 3.2 8.2 38.8 2.7 5.4 4.7 2.8 1.8 1.4 7.1 3.6 12.1 4.3 6.3 11.0 2.1 2.3 6.8 7.7 0.0 3.6 0.8 4.0 4.1 4.3 4.8 2.5 10.2 6.1 3.0 3.1 7.1 6.2 1.3 2.1 5.7 1.6 11.6 3.3 12.0 8.1 0.0 15.8 33.5 5.5 2.5 15.7 1.8 149.9 13.3 1.4 2.1 22.1 36.4 10.1 11.5 3.0 3.8 8.5 2.3 0.8 3.6 0.9 6.6 1.6 3.0 0.3 2.5 4.3 7.5 2.3 2.5 2.0 6.5 13.7 ZNF74 "Cos52, Zfp520, ZNF520" ENSG00000185252 "Zinc finger protein 74" Q16587 22 20394115-20408461 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "K-562: 47.9" HPA003354 Approved Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Actin filaments" "HPA003354: AB_1080747" "unprognostic (1.40e-1)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (1.12e-1)" "unprognostic (2.76e-2)" "unprognostic (1.02e-1)" "unprognostic (8.13e-3)" "unprognostic (1.76e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-1)" "unprognostic (1.20e-3)" "unprognostic (3.80e-2)" "unprognostic (1.10e-1)" "unprognostic (5.58e-2)" "unprognostic (3.04e-1)" "unprognostic (7.91e-2)" "unprognostic (1.44e-3)" 1.7 2.4 5.0 1.2 5.1 0.6 2.1 4.4 5.2 4.5 3.9 4.3 1.3 4.7 1.9 3.2 3.1 0.8 2.3 5.1 5.2 2.8 2.4 1.9 1.5 4.8 4.8 4.4 4.2 2.7 5.4 1.5 4.8 3.6 1.4 1.7 2.9 3.0 4.7 2.9 2.2 2.4 4.4 2.6 3.1 1.3 5.2 2.5 2.5 2.4 1.1 3.9 3.0 5.2 4.3 4.1 10.4 15.8 2.9 2.8 8.2 4.0 2.9 4.8 4.5 5.7 2.0 0.1 5.6 3.2 1.6 5.2 7.8 5.1 2.7 2.8 17.8 4.9 2.0 8.1 4.8 10.7 5.1 3.1 8.6 3.7 4.2 3.6 4.8 9.3 47.9 0.1 3.4 7.1 10.2 6.6 11.6 8.9 7.2 14.0 6.1 1.6 3.1 4.6 22.8 14.1 4.4 7.9 9.3 5.2 3.6 5.1 3.4 4.6 9.5 5.8 3.0 5.2 6.2 0.1 1.1 6.1 4.0 0.0 1.2 0.9 2.0 1.0 1.6 1.1 1.5 2.4 1.9 1.0 1.8 1.7 0.0 3.8 0.7 1.3 1.4 1.9 5.0 5.1 4.4 5.2 5.1 5.2 4.8 4.8 4.8 4.4 5.2 5.2 1.4 3.2 2.0 3.6 2.1 1.5 1.9 1.6 2.8 5.1 3.6 3.0 3.1 2.8 2.5 0.0 2.1 3.1 3.8 0.9 3.9 3.8 0.5 2.3 3.7 1.7 4.2 2.1 8.5 2.4 4.6 3.5 3.1 2.0 0.0 5.6 2.5 1.7 2.2 3.3 8.8 2.3 2.0 0.6 0.3 0.3 7.2 1.0 0.0 2.8 1.6 2.6 3.1 6.0 6.6 2.5 1.0 4.9 0.9 4.0 1.5 1.7 0.6 2.1 6.6 2.7 3.2 4.3 3.0 1.8 1.0 1.1 2.7 4.4 2.8 1.1 ZNF814 ENSG00000204514 "Zinc finger protein 814" B7Z6K7 19 57848731-57889074 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 32.5;U-266/84: 33.4" "HPA043800, HPA053762, HPA072145" Approved Uncertain Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA043800: AB_2678675, HPA053762: AB_2682252, HPA072145: " "unprognostic (3.74e-2)" "unprognostic (1.24e-1)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (6.01e-2)" "unprognostic (2.12e-2)" "unprognostic (1.03e-1)" "unprognostic (4.69e-2)" "unprognostic (6.78e-4)" "unprognostic (5.05e-3)" "unprognostic (2.41e-4)" "unprognostic (1.56e-2)" "unprognostic (4.99e-4)" "unprognostic (3.94e-1)" "unprognostic (2.33e-1)" "unprognostic (1.08e-1)" "unprognostic (1.54e-5)" 6.4 14.5 9.2 4.5 7.8 10.4 8.1 24.8 8.3 5.5 7.3 7.6 6.6 5.2 6.9 5.2 8.5 4.5 12.9 9.2 5.2 14.5 13.4 6.3 8.7 6.3 5.2 7.4 7.2 9.7 14.2 4.9 5.7 12.6 4.8 13.8 8.7 5.5 10.0 9.5 9.2 4.0 1.2 13.0 5.4 11.2 6.6 9.5 14.7 5.7 8.1 6.3 5.4 7.1 1.6 4.0 11.6 16.6 1.2 1.1 3.0 4.1 2.7 4.4 0.6 2.0 1.6 8.9 2.7 3.8 4.5 1.3 0.7 8.8 5.4 1.6 7.9 6.6 7.0 2.4 4.8 7.8 8.2 7.3 7.9 1.6 1.7 7.8 1.1 3.6 1.8 3.6 7.3 1.7 25.2 3.6 32.5 0.9 5.1 3.1 1.3 15.6 3.8 6.2 4.7 11.8 1.4 3.2 6.1 23.5 8.0 2.5 2.5 10.3 3.5 2.4 2.2 10.1 33.4 22.5 2.6 4.3 12.9 4.6 8.2 9.7 5.4 9.7 14.0 37.4 14.2 11.7 11.9 38.7 22.4 18.5 5.4 24.8 6.0 27.9 4.2 7.4 9.2 7.8 24.8 8.3 9.2 5.2 6.3 5.2 5.7 1.2 6.6 7.1 6.2 0.0 1.5 4.6 15.6 6.8 10.5 7.3 4.0 22.7 11.5 9.8 12.9 21.5 10.1 12.9 47.9 13.2 10.8 5.0 17.6 8.0 46.5 13.9 6.6 7.6 4.9 5.9 10.9 1.4 18.6 5.5 6.1 20.4 16.5 12.6 14.6 15.3 13.0 20.2 12.3 8.7 14.2 2.8 7.9 19.5 4.1 6.5 10.6 4.7 5.9 9.4 13.4 7.5 10.1 1.7 17.8 7.2 5.9 8.4 10.5 44.0 8.4 35.9 19.7 5.7 6.6 14.1 10.9 3.5 13.1 11.6 9.2 8.9 22.1 12.6 ZNF875 HKR1 ENSG00000181666 "Zinc finger protein 875" P10072 19 37312837-37369365 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 141.0" "Cell type enhanced" "Detected in some" "Adipocytes: 5.1;Cardiomyocytes: 19.8;Cytotrophoblasts: 11.0;Extravillous trophoblasts: 5.7;Hofbauer cells: 7.3;Syncytiotrophoblasts: 9.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA036126, HPA044855" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Mitochondria" "HPA036126: AB_10670708, HPA044855: AB_2679113" "unprognostic (1.04e-2)" "unprognostic (9.68e-2)" "unprognostic (1.75e-1)" "unprognostic (3.58e-1)" "unprognostic (2.78e-1)" "unprognostic (4.81e-2)" "unprognostic (2.29e-1)" "unprognostic (1.02e-3)" "unprognostic (4.92e-3)" "unprognostic (9.82e-2)" "prognostic favorable (4.41e-4)" "prognostic unfavorable (5.18e-5)" "unprognostic (1.34e-1)" "unprognostic (5.04e-2)" "unprognostic (2.00e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-3)" 18.9 37.4 29.0 10.8 26.2 14.8 25.9 36.8 30.9 24.1 46.5 22.6 8.3 20.4 23.9 17.4 23.9 14.4 31.9 28.0 30.3 34.0 18.3 18.7 16.7 25.4 26.5 28.1 20.0 31.8 36.5 18.3 26.4 39.4 14.0 141.0 27.1 19.2 21.3 28.4 19.4 17.4 19.3 27.9 21.1 30.4 28.7 19.2 37.9 18.1 18.9 21.7 22.0 30.2 7.8 19.7 24.9 32.3 18.0 15.1 17.2 13.2 20.0 23.7 25.8 10.0 9.1 27.8 31.4 14.0 11.1 6.6 16.5 17.7 24.9 14.5 28.4 9.8 26.9 10.4 23.3 8.6 23.9 23.4 21.5 16.4 35.4 23.8 14.8 19.9 1.9 1.6 17.6 16.0 20.0 17.7 51.0 13.9 11.3 13.7 10.7 10.9 21.2 31.9 32.1 42.5 13.1 16.7 16.9 36.2 24.1 17.4 13.6 18.8 13.1 14.2 21.0 34.9 40.4 29.8 2.2 10.7 21.3 12.8 4.5 7.4 7.6 5.8 14.9 11.1 10.6 11.5 6.9 12.6 14.3 12.0 4.1 11.4 4.0 8.4 13.9 6.8 29.0 26.2 36.8 30.9 28.0 30.3 25.4 26.5 26.4 19.3 28.7 30.2 5.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 11.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 5.7 2.2 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 9.9 0.4 0.0 0.0 0.0 ZNF98 "F7175, ZNF739" ENSG00000197360 "Zinc finger protein 98" A6NK75 19 22391019-22532485 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "ovary: 11.8;pancreas: 37.2" "Cell type enhanced" "Detected in many" "Astrocytes: 34.0;Distal tubular cells: 15.6;Early spermatids: 14.7;Granulosa cells: 12.9;Oligodendrocyte precursor cells: 10.6;Spermatocytes: 15.7;Spermatogonia: 21.1" "Cancer enriched" "Detected in some" 4 "testis cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.8;GAMG: 5.4;NB-4: 4.8;RPMI-8226: 1.9;SuSa: 2.1;T-47d: 3.4;U-2197: 3.6" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "unprognostic (1.11e-1)" "unprognostic (1.31e-2)" "unprognostic (6.95e-3)" "unprognostic (1.36e-3)" "unprognostic (3.07e-3)" "unprognostic (1.56e-1)" "unprognostic (7.20e-2)" "unprognostic (1.63e-1)" "unprognostic (1.81e-1)" "unprognostic (3.81e-2)" "unprognostic (1.99e-2)" "unprognostic (2.14e-1)" "unprognostic (2.66e-1)" "unprognostic (7.56e-2)" 1.0 0.6 1.8 0.2 5.6 0.2 3.8 0.6 10.1 3.3 0.0 0.2 0.1 1.2 5.7 0.2 2.1 0.4 0.6 2.7 4.0 2.0 0.0 0.2 0.4 1.6 1.9 11.8 37.2 3.9 0.3 0.5 1.6 0.8 0.1 0.6 0.8 0.6 0.0 0.1 0.1 1.3 0.2 0.2 0.3 7.6 1.4 0.0 4.7 0.2 0.0 0.5 0.2 5.8 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.8 0.0 5.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.1 4.8 1.0 0.0 0.2 0.3 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 3.4 1.1 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 5.6 0.6 10.1 2.7 4.0 1.6 1.9 1.6 0.2 1.4 5.8 1.2 0.0 0.0 34.0 0.1 0.0 0.4 0.0 0.0 1.4 2.9 2.5 1.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 15.6 3.1 14.7 0.3 1.6 0.4 0.0 0.0 2.5 1.4 0.4 1.2 0.0 0.5 0.0 12.9 0.0 0.0 0.1 1.7 0.5 0.0 0.0 0.0 0.0 3.5 1.2 0.1 0.0 1.9 0.0 1.0 0.0 10.6 5.2 0.3 0.0 1.9 0.0 0.1 0.0 1.7 0.0 0.1 0.0 0.0 1.0 15.7 21.1 0.0 0.0 0.4 0.0 8.2 0.0 0.4 ZNFX1 "FLJ11277, KIAA1404" ENSG00000124201 "Zinc finger NFX1-type containing 1" Q9P2E3 20 49237946-49278426 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+ SV40 Large T+: 132.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046629 Approved Approved Mitochondria No No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA046629: AB_2616451" "unprognostic (1.03e-1)" "unprognostic (2.80e-1)" "unprognostic (1.15e-1)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (3.58e-1)" "unprognostic (2.62e-2)" "unprognostic (2.55e-1)" "unprognostic (3.85e-2)" "unprognostic (1.49e-1)" "unprognostic (3.13e-2)" "unprognostic (2.09e-1)" "unprognostic (1.50e-1)" "unprognostic (2.79e-1)" "unprognostic (8.71e-3)" "unprognostic (7.40e-2)" "unprognostic (7.86e-2)" 17.1 9.4 9.7 14.3 10.7 28.7 12.4 9.1 9.8 10.1 12.1 11.2 11.0 11.3 9.0 8.1 10.7 14.1 13.2 8.9 9.4 11.8 9.6 18.8 14.2 14.0 11.0 9.9 9.2 13.0 8.5 12.3 10.8 9.7 10.5 8.7 10.3 9.6 15.5 11.8 12.4 13.6 13.3 19.1 11.4 13.4 11.9 13.1 13.8 14.5 13.4 16.5 9.0 11.3 16.3 24.9 5.8 8.2 31.4 24.5 9.8 21.6 50.9 132.7 54.9 28.4 13.2 13.5 27.3 43.5 37.6 30.7 10.8 29.3 45.1 12.8 3.6 16.0 18.1 12.5 27.2 13.0 18.7 26.3 26.9 29.7 22.0 24.3 20.3 8.0 12.4 16.2 33.6 6.8 14.2 8.7 5.6 14.0 20.7 8.9 19.6 3.8 21.8 22.1 5.9 4.3 31.6 61.1 22.4 7.1 15.7 10.8 50.9 64.8 18.3 23.8 21.1 10.7 4.0 7.2 26.0 8.7 14.6 19.3 12.3 20.1 13.5 15.2 12.0 9.4 13.6 13.1 9.1 7.1 12.9 10.0 51.9 9.9 27.1 5.2 11.0 11.5 9.7 10.7 9.1 9.8 8.9 9.4 14.0 11.0 10.8 13.3 11.9 11.3 36.5 41.7 27.2 10.4 25.8 27.8 21.2 14.4 19.4 15.7 13.7 11.2 14.4 10.0 24.8 20.2 10.4 6.1 18.7 28.0 0.0 23.9 37.4 15.9 17.9 38.1 13.1 10.7 12.5 22.7 7.0 28.0 28.5 18.6 27.3 8.1 29.3 13.4 15.1 11.8 11.7 14.2 16.2 26.4 38.0 21.1 22.7 34.2 19.6 15.0 30.2 29.5 17.5 7.1 9.9 32.3 21.8 27.1 9.3 32.8 18.7 6.7 42.8 15.1 0.0 27.8 29.9 42.0 16.3 16.2 21.7 11.4 31.4 10.2 10.4 35.7 ZPBP "SP38, ZPBP1" ENSG00000042813 "Zona pellucida binding protein" Q9BS86 7 49850421-50121329 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "testis: 143.1" "Group enriched" "Detected in some" 7 "Early spermatids: 973.0;Spermatocytes: 691.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058673 Enhanced "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA058673: AB_2683794" "unprognostic (1.16e-1)" "unprognostic (6.46e-2)" "unprognostic (7.80e-2)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.15e-7)" "unprognostic (9.49e-2)" "unprognostic (2.34e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 143.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 15.0 0.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 973.0 0.1 0.1 0.4 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 22.9 0.0 0.0 0.0 0.0 116.0 11.1 0.4 0.0 1.9 0.0 1.9 0.0 9.0 0.5 0.1 0.0 7.9 0.0 0.2 0.0 0.5 0.6 20.2 6.6 0.0 0.0 691.6 17.1 0.0 0.3 0.0 0.0 0.2 0.0 0.2 ZPBP2 "MGC41930, ZPBPL" ENSG00000186075 "Zona pellucida binding protein 2" Q6X784 17 39868202-39877896 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 100 "testis: 95.3" "Group enriched" "Detected in some" 5 "Early spermatids: 273.9;Spermatocytes: 598.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.3;U-698: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027997, HPA053070" Enhanced "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA027997: AB_1859488, HPA053070: AB_2682033" "unprognostic (2.14e-2)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (2.87e-1)" "unprognostic (5.39e-1)" "unprognostic (2.54e-3)" 0.1 0.1 0.4 0.3 0.2 0.3 0.2 0.7 0.6 0.0 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.3 0.5 0.0 0.2 0.1 0.7 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.6 0.1 0.1 0.4 0.3 0.1 0.0 0.0 0.3 0.2 95.3 0.3 0.1 0.1 0.1 0.9 0.1 0.0 0.6 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.2 0.0 1.3 0.1 0.2 0.1 0.0 0.2 0.1 0.2 0.3 0.6 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.3 0.4 0.3 0.3 0.2 0.4 1.0 0.1 0.1 0.4 0.1 0.0 0.2 0.1 0.5 0.1 0.0 0.2 0.1 0.1 0.2 0.0 0.4 0.1 4.9 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.7 0.6 0.3 0.5 0.2 0.1 0.2 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 273.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.2 7.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 598.2 19.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 ZSCAN18 "FLJ12895, ZNF447" ENSG00000121413 "Zinc finger and SCAN domain containing 18" Q8TBC5 19 58083838-58118427 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 112.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 128.4;SCLC-21H: 59.3;U-266/84: 46.6" "Low region specificity" "Detected in all" HPA024318 Supported Approved Nucleoplasm No No "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA024318: AB_1859494" "unprognostic (1.85e-2)" "unprognostic (3.48e-2)" "unprognostic (7.07e-2)" "unprognostic (6.45e-3)" "unprognostic (1.28e-1)" "unprognostic (1.22e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" "unprognostic (2.24e-1)" "unprognostic (8.27e-2)" "unprognostic (2.59e-3)" "unprognostic (1.59e-1)" "prognostic favorable (3.95e-7)" "unprognostic (3.68e-2)" "unprognostic (7.23e-2)" "unprognostic (3.70e-1)" "unprognostic (9.04e-2)" 29.5 31.2 74.2 8.3 74.5 5.8 32.8 56.3 74.7 53.0 61.8 60.0 9.9 63.1 20.8 21.3 66.3 14.9 55.7 71.6 78.0 56.1 14.4 28.8 9.4 71.9 70.0 63.5 22.9 27.9 82.8 14.9 68.8 46.3 6.2 36.9 23.8 28.9 23.7 29.0 28.9 18.8 63.2 28.1 32.4 42.5 79.8 10.3 60.8 13.2 6.7 49.5 34.6 67.3 0.2 1.7 14.4 35.2 1.7 1.9 32.4 9.5 0.2 12.8 2.3 0.0 8.7 3.8 18.8 13.6 14.4 0.2 1.2 7.7 12.4 0.1 128.4 0.4 0.1 0.2 25.7 0.0 25.8 23.1 0.4 9.5 0.0 17.1 0.9 9.3 0.2 1.4 18.1 0.0 18.9 7.2 22.6 0.0 0.0 21.8 0.0 1.5 11.8 29.1 59.3 13.8 0.0 0.5 0.1 12.5 39.5 0.0 0.0 0.6 15.0 15.4 0.1 15.2 46.6 0.1 0.0 0.2 10.5 1.0 0.2 1.3 0.1 0.1 0.8 0.6 0.6 0.6 0.3 1.4 0.9 0.8 1.4 0.8 0.2 0.8 0.0 0.3 74.2 74.5 56.3 74.7 71.6 78.0 71.9 70.0 68.8 63.2 79.8 67.3 30.6 16.0 26.9 31.0 24.9 12.1 51.2 6.7 7.4 77.5 22.5 25.0 44.3 25.8 26.2 42.3 33.3 45.9 10.1 3.7 15.6 25.1 52.3 46.9 26.8 33.2 26.5 3.4 29.5 5.8 8.6 28.5 11.7 24.0 23.5 39.8 33.5 4.1 9.0 112.7 26.4 14.7 10.2 3.2 6.4 75.9 40.0 6.0 10.6 13.1 6.0 73.0 25.7 21.6 40.7 5.9 13.1 58.6 3.6 38.4 7.3 11.1 36.7 110.5 19.7 32.6 30.1 30.0 27.9 6.5 12.1 65.7 15.8 39.3 10.5 32.6 ZSCAN29 "FLJ35867, Zfp690, ZNF690" ENSG00000140265 "Zinc finger and SCAN domain containing 29" Q8IWY8 15 43358172-43371025 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007241, HPA011109" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Actin filaments" "HPA007241: AB_10600420, HPA011109: AB_10611525" "unprognostic (3.90e-2)" "unprognostic (2.70e-1)" "unprognostic (1.15e-1)" "unprognostic (4.06e-2)" "unprognostic (2.21e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" "unprognostic (5.25e-1)" "unprognostic (2.12e-2)" "unprognostic (4.77e-3)" "unprognostic (1.64e-1)" "unprognostic (1.44e-3)" "unprognostic (9.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (8.33e-2)" "unprognostic (3.43e-2)" 6.3 5.6 7.9 8.6 10.1 5.6 6.8 8.1 7.4 7.2 8.1 7.6 8.8 8.9 5.2 7.2 6.4 6.0 5.5 6.6 7.4 5.7 6.9 6.9 10.7 9.3 9.7 7.4 11.4 7.7 5.5 8.1 8.9 6.8 7.6 13.6 8.5 6.5 9.7 5.8 9.9 6.4 7.7 9.0 8.8 17.3 8.5 10.7 7.2 8.5 10.4 6.6 6.0 10.3 11.7 12.5 28.9 17.9 10.0 10.5 15.6 9.0 13.9 15.6 16.2 19.7 8.1 11.4 14.7 11.1 12.6 33.7 21.5 11.0 13.9 29.6 11.8 25.1 20.5 15.5 11.1 17.3 21.2 9.3 19.0 10.6 14.9 11.0 8.0 17.3 23.7 13.5 12.7 7.4 16.7 14.2 14.5 17.1 9.6 25.7 16.1 14.0 9.1 13.9 20.6 22.2 13.9 22.5 10.4 14.5 15.8 26.6 9.1 18.3 14.4 14.0 16.4 25.8 38.4 21.6 10.7 16.9 14.1 0.4 0.3 3.1 0.4 0.4 0.3 0.8 0.4 0.3 0.4 0.5 0.2 0.6 0.7 1.0 0.3 0.3 0.8 0.3 7.9 10.1 8.1 7.4 6.6 7.4 9.3 9.7 8.9 7.7 8.5 10.3 3.5 6.4 7.9 6.8 5.8 3.6 2.6 3.7 4.6 10.8 4.8 4.8 7.8 4.3 7.8 7.3 27.1 5.1 7.1 11.0 0.0 5.4 81.7 5.0 8.2 4.9 6.1 1.3 6.4 7.1 4.4 5.8 9.7 7.8 0.0 6.5 3.9 7.2 5.8 13.5 5.2 8.1 4.1 10.6 3.7 20.7 6.8 4.8 5.4 9.4 6.7 5.5 10.3 10.1 10.2 8.7 5.0 6.0 3.3 3.9 7.7 2.6 5.2 18.0 0.0 4.9 3.8 12.0 6.7 4.4 3.1 3.8 4.2 2.8 7.0 2.4